ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0035673 oligopeptide transmembrane transporter activity 3/151 11/18367 8.56361818620597e-05 0.0158717521875595 SLC15A4/SLC15A1/GJA1 3 GO:0051219 phosphoprotein binding 6/151 88/18367 8.69685051373125e-05 0.0158717521875595 SNCA/PCIF1/CBX4/PLAT/PIH1D1/SOCS3 6 GO:1904680 peptide transmembrane transporter activity 3/151 15/18367 0.000230509709573422 0.0160272626159885 SLC15A4/SLC15A1/GJA1 3 GO:0004860 protein kinase inhibitor activity 5/151 70/18367 0.000276700055431621 0.0160272626159885 SOCS1/SNCA/SH3BP5/HEXIM1/SOCS3 5 GO:0015174 basic amino acid transmembrane transporter activity 3/151 17/18367 0.000340364938073873 0.0160272626159885 SLC15A4/SLC7A2/SLC25A29 3 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 12/151 450/18367 0.000350899847736589 0.0160272626159885 PLSCR1/CASZ1/TFCP2L1/FOS/RFXANK/MAFF/SMAD3/HOXD8/MYC/DLX5/HIF1A/CEBPB 12 GO:0019210 kinase inhibitor activity 5/151 74/18367 0.000358713481924059 0.0160272626159885 SOCS1/SNCA/SH3BP5/HEXIM1/SOCS3 5 GO:0001046 core promoter sequence-specific DNA binding 4/151 42/18367 0.000385364663334342 0.0160272626159885 FOS/MYC/PIH1D1/CEBPB 4 GO:0001216 DNA-binding transcription activator activity 12/151 456/18367 0.000395192776832593 0.0160272626159885 PLSCR1/CASZ1/TFCP2L1/FOS/RFXANK/MAFF/SMAD3/HOXD8/MYC/DLX5/HIF1A/CEBPB 12 GO:0046332 SMAD binding 5/151 79/18367 0.00048564003767677 0.0163548232792703 FOS/PMEPA1/TOB1/SMAD3/DAB2 5 GO:0000287 magnesium ion binding 8/151 221/18367 0.000492885085128693 0.0163548232792703 PLSCR1/SNCA/GEM/ATP11A/STK4/MOV10L1/GCLC/PKM 8 GO:0070412 R-SMAD binding 3/151 23/18367 0.000854972622001005 0.0260054172525306 FOS/PMEPA1/SMAD3 3 GO:0044389 ubiquitin-like protein ligase binding 9/151 316/18367 0.00123118085974278 0.034567770292778 PPARGC1A/HSPA1A/FZD8/PARP9/PIAS2/HSPA1B/SMAD3/HIF1A/CEBPB 9 GO:0019887 protein kinase regulator activity 7/151 204/18367 0.00150861138839921 0.0393316540546936 SOCS1/SNCA/CCNH/STK4/SH3BP5/HEXIM1/SOCS3 7 GO:0005520 insulin-like growth factor binding 3/151 29/18367 0.00170151384341053 0.0414035035229897 HTRA3/IGFBP4/IGFBP6 3 GO:0042887 amide transmembrane transporter activity 3/151 35/18367 0.00293998968975019 0.0648627239450646 SLC15A4/SLC15A1/GJA1 3 GO:0019207 kinase regulator activity 7/151 233/18367 0.00318463907945686 0.0648627239450646 SOCS1/SNCA/CCNH/STK4/SH3BP5/HEXIM1/SOCS3 7 GO:0046915 transition metal ion transmembrane transporter activity 3/151 37/18367 0.00344869634519819 0.0648627239450646 SLC25A37/SLC30A1/SLC39A14 3 GO:0061665 SUMO ligase activity 2/151 11/18367 0.00351749875541906 0.0648627239450646 CBX4/PIAS2 2 GO:0001618 virus receptor activity 4/151 76/18367 0.00356037594268703 0.0648627239450646 PLSCR1/HSPA1A/CD55/HSPA1B 4 GO:0140272 exogenous protein binding 4/151 77/18367 0.00373182795300372 0.0648627239450646 PLSCR1/HSPA1A/CD55/HSPA1B 4 GO:0042826 histone deacetylase binding 5/151 127/18367 0.00400138433252467 0.0663866036987047 HSPA1A/RFXANK/HSPA1B/HIF1A/CEBPB 5 GO:0031994 insulin-like growth factor I binding 2/151 13/18367 0.00493496295839451 0.078315716513652 IGFBP4/IGFBP6 2 GO:0008013 beta-catenin binding 4/151 85/18367 0.00530888628125427 0.0807393121940753 BCL9L/GJA1/SMAD3/TRPC4 4 GO:0035259 glucocorticoid receptor binding 2/151 14/18367 0.00572653600882416 0.0836074257288327 SMAD3/CEBPB 2 GO:0070888 E-box binding 3/151 48/18367 0.00718852962412218 0.0973854101163979 ATOH8/MYC/HIF1A 3 GO:0008191 metalloendopeptidase inhibitor activity 2/151 16/18367 0.00747066159797025 0.0973854101163979 RARRES1/SPOCK1 2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity 2/151 16/18367 0.00747066159797025 0.0973854101163979 SOCS1/SOCS3 2 GO:0070628 proteasome binding 2/151 17/18367 0.00842136781928976 0.105993077725544 ZFAND1/PSMG1 2 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/151 56/18367 0.0109852439004086 0.124284863158852 SNCA/CST2/SPOCK1 3 GO:0005548 phospholipid transporter activity 3/151 57/18367 0.0115268525255756 0.124284863158852 PLSCR1/ATP11A/PRELID3B 3 GO:0031625 ubiquitin protein ligase binding 7/151 297/18367 0.0115393943381332 0.124284863158852 PPARGC1A/HSPA1A/FZD8/PIAS2/HSPA1B/SMAD3/HIF1A 7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/151 20/18367 0.0115772201298657 0.124284863158852 FOS/CEBPB 2 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/151 20/18367 0.0115772201298657 0.124284863158852 SOCS1/SOCS3 2 GO:0005385 zinc ion transmembrane transporter activity 2/151 21/18367 0.0127274692522099 0.132729322201618 SLC30A1/SLC39A14 2 GO:0015179 L-amino acid transmembrane transporter activity 3/151 61/18367 0.0138454946163185 0.140377931526563 SLC15A4/SLC7A2/SLC25A29 3 GO:0140297 DNA-binding transcription factor binding 8/151 394/18367 0.0163450252900535 0.154058475838203 ATOH8/PPARGC1A/FOS/PARP9/SMAD3/MYC/HIF1A/CEBPB 8 GO:0015295 solute:proton symporter activity 2/151 24/18367 0.016461042623808 0.154058475838203 SLC15A4/SLC15A1 2 GO:0019789 SUMO transferase activity 2/151 24/18367 0.016461042623808 0.154058475838203 CBX4/PIAS2 2 GO:0008514 organic anion transmembrane transporter activity 5/151 185/18367 0.0184831986420918 0.168659187609088 SLC15A4/SLC35B2/GJA1/SLC7A2/SLC25A29 5 GO:0003712 transcription coregulator activity 9/151 489/18367 0.0198920847764589 0.177088071790427 PPARGC1A/HSPA1A/LPIN3/CBFB/BCL9L/PARP9/CBX4/TOB1/PIAS2 9 GO:0031072 heat shock protein binding 4/151 129/18367 0.0219140952422996 0.187321167193763 SNCA/HSPA1A/HSPA1B/HIF1A 4 GO:0001968 fibronectin binding 2/151 28/18367 0.022067973121457 0.187321167193763 VEGFA/IGFBP6 2 GO:0051787 misfolded protein binding 2/151 29/18367 0.0235765997346457 0.195578611435129 HSPA1A/HSPA1B 2 GO:0016887 ATP hydrolysis activity 6/151 272/18367 0.0250968726489745 0.203563522597237 HSPA1A/DDX41/ATP11A/ATAD1/MOV10L1/HSPA1B 6 GO:0001223 transcription coactivator binding 2/151 32/18367 0.0283465140860366 0.220137822157519 SMAD3/HIF1A 2 GO:0071889 14-3-3 protein binding 2/151 32/18367 0.0283465140860366 0.220137822157519 HLA-F/IRS2 2 GO:0019838 growth factor binding 4/151 141/18367 0.0291483060879322 0.221648577543651 HTRA3/TSKU/IGFBP4/IGFBP6 4 GO:0016922 nuclear receptor binding 4/151 144/18367 0.0311531399792196 0.23205910392684 PPARGC1A/SMAD3/HIF1A/CEBPB 4 GO:0015171 amino acid transmembrane transporter activity 3/151 84/18367 0.0320033287047916 0.233624299544979 SLC15A4/SLC7A2/SLC25A29 3 GO:0097718 disordered domain specific binding 2/151 36/18367 0.0352477126728993 0.252263041678593 HSPA1A/GJA1 2 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 6/151 299/18367 0.0372932590538232 0.26176999143549 PPARGC1A/FOS/PARP9/SMAD3/HIF1A/CEBPB 6 GO:0140303 intramembrane lipid transporter activity 2/151 38/18367 0.0389171796565863 0.268014539144415 PLSCR1/ATP11A 2 GO:0019825 oxygen binding 2/151 39/18367 0.0408041589842675 0.26887316897339 HBG1/SOD2 2 GO:0061134 peptidase regulator activity 5/151 230/18367 0.0415855929446368 0.26887316897339 SNCA/CST2/RARRES1/CTSH/SPOCK1 5 GO:0043014 alpha-tubulin binding 2/151 40/18367 0.0427250515081003 0.26887316897339 PPARGC1A/SNCA 2 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/151 40/18367 0.0427250515081003 0.26887316897339 SNCA/CTSH 2 GO:0044183 protein folding chaperone 2/151 40/18367 0.0427250515081003 0.26887316897339 HSPA1A/HSPA1B 2 GO:0008509 anion transmembrane transporter activity 6/151 314/18367 0.045470331071698 0.281299505782539 SLC15A4/SLC35B2/GJA1/SLC7A2/SLC39A14/SLC25A29 6 GO:0005246 calcium channel regulator activity 2/151 43/18367 0.0486844817977286 0.296163930936183 GEM/SLC30A1 2 GO:0015294 solute:cation symporter activity 3/151 104/18367 0.0544127438426363 0.325584450861676 SLC15A4/SLC15A1/SLC39A14 3 GO:0004252 serine-type endopeptidase activity 4/151 174/18367 0.0555974265302507 0.327307430379702 CFI/HTRA3/CTSH/PLAT 4 GO:0016763 pentosyltransferase activity 2/151 49/18367 0.061430304456408 0.346774515528983 MTAP/PARP9 2 GO:0004866 endopeptidase inhibitor activity 4/151 180/18367 0.061442841851248 0.346774515528983 SNCA/CST2/RARRES1/SPOCK1 4 GO:0047485 protein N-terminus binding 3/151 110/18367 0.0622761384245869 0.346774515528983 SNCA/HSPA1A/HSPA1B 3 GO:0032182 ubiquitin-like protein binding 3/151 111/18367 0.0636355299815211 0.346774515528983 CBX4/SMAD3/DCUN1D1 3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/151 50/18367 0.0636545001107996 0.346774515528983 CCNH/HEXIM1 2 GO:1901682 sulfur compound transmembrane transporter activity 2/151 52/18367 0.0681830943356431 0.352784010313972 SLC35B2/GJA1 2 GO:0003714 transcription corepressor activity 4/151 187/18367 0.0686577169018598 0.352784010313972 HSPA1A/PARP9/CBX4/TOB1 4 GO:0030414 peptidase inhibitor activity 4/151 187/18367 0.0686577169018598 0.352784010313972 SNCA/CST2/RARRES1/SPOCK1 4 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/151 53/18367 0.0704863279780563 0.352784010313972 SLC15A4/SLC35B2 2 GO:0008236 serine-type peptidase activity 4/151 191/18367 0.0729689487241909 0.352784010313972 CFI/HTRA3/CTSH/PLAT 4 GO:0061135 endopeptidase regulator activity 4/151 194/18367 0.076291096666683 0.352784010313972 SNCA/CST2/RARRES1/SPOCK1 4 GO:0106310 protein serine kinase activity 6/151 360/18367 0.0770954435922044 0.352784010313972 TRIO/STK4/PRKAA2/MAP3K4/STK35/TLK1 6 GO:0017171 serine hydrolase activity 4/151 195/18367 0.0774152332960113 0.352784010313972 CFI/HTRA3/CTSH/PLAT 4 GO:0045309 protein phosphorylated amino acid binding 2/151 56/18367 0.077544945480493 0.352784010313972 PCIF1/SOCS3 2 GO:0050840 extracellular matrix binding 2/151 56/18367 0.077544945480493 0.352784010313972 SHH/VEGFA 2 GO:0005384 manganese ion transmembrane transporter activity 1/151 10/18367 0.0792555858787553 0.352784010313972 SLC39A14 1 GO:0015173 aromatic amino acid transmembrane transporter activity 1/151 10/18367 0.0792555858787553 0.352784010313972 SLC15A4 1 GO:0015279 store-operated calcium channel activity 1/151 10/18367 0.0792555858787553 0.352784010313972 TRPC4 1 GO:0016595 glutamate binding 1/151 10/18367 0.0792555858787553 0.352784010313972 GCLC 1 GO:0031720 haptoglobin binding 1/151 10/18367 0.0792555858787553 0.352784010313972 HBG1 1 GO:0017128 phospholipid scramblase activity 1/151 11/18367 0.0868293945910888 0.360718661303617 PLSCR1 1 GO:0019855 calcium channel inhibitor activity 1/151 11/18367 0.0868293945910888 0.360718661303617 SLC30A1 1 GO:1901474 azole transmembrane transporter activity 1/151 11/18367 0.0868293945910888 0.360718661303617 SLC15A4 1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/151 60/18367 0.0872833539703829 0.360718661303617 DUS1L/PTGR2 2 GO:0017124 SH3 domain binding 3/151 130/18367 0.0919633494650309 0.360718661303617 PLSCR1/SH3BP5/GJA1 3 GO:1990841 promoter-specific chromatin binding 2/151 62/18367 0.0922830821058873 0.360718661303617 PPARGC1A/SMAD3 2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/151 12/18367 0.0943413122973835 0.360718661303617 HEXIM1 1 GO:0008174 mRNA methyltransferase activity 1/151 12/18367 0.0943413122973835 0.360718661303617 PCIF1 1 GO:0030955 potassium ion binding 1/151 12/18367 0.0943413122973835 0.360718661303617 PKM 1 GO:0042975 peroxisome proliferator activated receptor binding 1/151 12/18367 0.0943413122973835 0.360718661303617 PPARGC1A 1 GO:0070410 co-SMAD binding 1/151 12/18367 0.0943413122973835 0.360718661303617 SMAD3 1 GO:0097677 STAT family protein binding 1/151 12/18367 0.0943413122973835 0.360718661303617 PARP9 1 GO:0016836 hydro-lyase activity 2/151 64/18367 0.0973643533985671 0.360718661303617 ALAD/CA12 2 GO:0004674 protein serine/threonine kinase activity 6/151 386/18367 0.0993626745380983 0.360718661303617 TRIO/STK4/PRKAA2/MAP3K4/STK35/TLK1 6 GO:0030145 manganese ion binding 2/151 65/18367 0.0999343236171341 0.360718661303617 B4GALT1/SOD2 2 GO:0004312 fatty acid synthase activity 1/151 13/18367 0.101791841408966 0.360718661303617 MCAT 1 GO:0008195 phosphatidate phosphatase activity 1/151 13/18367 0.101791841408966 0.360718661303617 LPIN3 1 GO:0039706 co-receptor binding 1/151 13/18367 0.101791841408966 0.360718661303617 DKK1 1 GO:0070679 inositol 1,4,5 trisphosphate binding 1/151 13/18367 0.101791841408966 0.360718661303617 TRPC4 1 GO:0072542 protein phosphatase activator activity 1/151 13/18367 0.101791841408966 0.360718661303617 PPP1R15A 1 GO:0140333 glycerophospholipid flippase activity 1/151 13/18367 0.101791841408966 0.360718661303617 ATP11A 1 GO:0004089 carbonate dehydratase activity 1/151 14/18367 0.1091814802859 0.365607709214253 CA12 1 GO:0005172 vascular endothelial growth factor receptor binding 1/151 14/18367 0.1091814802859 0.365607709214253 VEGFA 1 GO:0005344 oxygen carrier activity 1/151 14/18367 0.1091814802859 0.365607709214253 HBG1 1 GO:0015562 efflux transmembrane transporter activity 1/151 14/18367 0.1091814802859 0.365607709214253 GJA1 1 GO:0070411 I-SMAD binding 1/151 14/18367 0.1091814802859 0.365607709214253 SMAD3 1 GO:0071837 HMG box domain binding 1/151 14/18367 0.1091814802859 0.365607709214253 DLX5 1 GO:0015293 symporter activity 3/151 144/18367 0.115608761044277 0.376339946843751 SLC15A4/SLC15A1/SLC39A14 3 GO:0005161 platelet-derived growth factor receptor binding 1/151 15/18367 0.116510723269435 0.376339946843751 VEGFA 1 GO:0016805 dipeptidase activity 1/151 15/18367 0.116510723269435 0.376339946843751 CNDP2 1 GO:0042813 Wnt-activated receptor activity 1/151 15/18367 0.116510723269435 0.376339946843751 FZD8 1 GO:0005159 insulin-like growth factor receptor binding 1/151 16/18367 0.1237800607142 0.378465976686136 SOCS1 1 GO:0032183 SUMO binding 1/151 16/18367 0.1237800607142 0.378465976686136 CBX4 1 GO:0035173 histone kinase activity 1/151 16/18367 0.1237800607142 0.378465976686136 PRKAA2 1 GO:0140327 flippase activity 1/151 16/18367 0.1237800607142 0.378465976686136 ATP11A 1 GO:1990404 protein ADP-ribosylase activity 1/151 16/18367 0.1237800607142 0.378465976686136 PARP9 1 GO:0008484 sulfuric ester hydrolase activity 1/151 17/18367 0.130989979020132 0.378465976686136 IDS 1 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/151 17/18367 0.130989979020132 0.378465976686136 CTSH 1 GO:0015095 magnesium ion transmembrane transporter activity 1/151 17/18367 0.130989979020132 0.378465976686136 SLC41A2 1 GO:0031420 alkali metal ion binding 1/151 17/18367 0.130989979020132 0.378465976686136 PKM 1 GO:0032393 MHC class I receptor activity 1/151 17/18367 0.130989979020132 0.378465976686136 CTSH 1 GO:0003724 RNA helicase activity 2/151 77/18367 0.132116122829889 0.378465976686136 DDX41/MOV10L1 2 GO:0038024 cargo receptor activity 2/151 77/18367 0.132116122829889 0.378465976686136 CFI/DAB2 2 GO:0005319 lipid transporter activity 3/151 154/18367 0.133750854439053 0.378465976686136 PLSCR1/ATP11A/PRELID3B 3 GO:0001221 transcription coregulator binding 2/151 78/18367 0.13489629555939 0.378465976686136 SMAD3/HIF1A 2 GO:0008186 ATP-dependent activity, acting on RNA 2/151 79/18367 0.137689630278667 0.378465976686136 DDX41/MOV10L1 2 GO:0016835 carbon-oxygen lyase activity 2/151 79/18367 0.137689630278667 0.378465976686136 ALAD/CA12 2 GO:0000295 adenine nucleotide transmembrane transporter activity 1/151 18/18367 0.138140960664162 0.378465976686136 SLC35B2 1 GO:0004550 nucleoside diphosphate kinase activity 1/151 18/18367 0.138140960664162 0.378465976686136 AK4 1 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/151 18/18367 0.138140960664162 0.378465976686136 SLC35B2 1 GO:1904047 S-adenosyl-L-methionine binding 1/151 18/18367 0.138140960664162 0.378465976686136 PCIF1 1 GO:0045296 cadherin binding 5/151 332/18367 0.138943673632719 0.378465976686136 HSPA1A/NDRG1/PACSIN2/PKM/TRPC4 5 GO:0042393 histone binding 4/151 244/18367 0.141994145294774 0.382018963198527 SNCA/PARP9/CBX4/PIH1D1 4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/151 19/18367 0.145233484231643 0.382018963198527 GALNT15 1 GO:0035615 clathrin adaptor activity 1/151 19/18367 0.145233484231643 0.382018963198527 DAB2 1 GO:0008083 growth factor activity 3/151 162/18367 0.148928585152728 0.382018963198527 GH2/VEGFA/DKK1 3 GO:0046943 carboxylic acid transmembrane transporter activity 3/151 163/18367 0.150864029218053 0.382018963198527 SLC15A4/SLC7A2/SLC25A29 3 GO:0030165 PDZ domain binding 2/151 84/18367 0.15183992000358 0.382018963198527 FZD8/GJA1 2 GO:0016505 peptidase activator activity involved in apoptotic process 1/151 20/18367 0.152268024447526 0.382018963198527 CTSH 1 GO:0019211 phosphatase activator activity 1/151 20/18367 0.152268024447526 0.382018963198527 PPP1R15A 1 GO:0050145 nucleoside monophosphate kinase activity 1/151 20/18367 0.152268024447526 0.382018963198527 AK4 1 GO:0070300 phosphatidic acid binding 1/151 20/18367 0.152268024447526 0.382018963198527 PACSIN2 1 GO:0140312 cargo adaptor activity 1/151 20/18367 0.152268024447526 0.382018963198527 DAB2 1 GO:0005342 organic acid transmembrane transporter activity 3/151 164/18367 0.152807585279411 0.382018963198527 SLC15A4/SLC7A2/SLC25A29 3 GO:0016209 antioxidant activity 2/151 86/18367 0.157578586947005 0.387496293704411 HBG1/SOD2 2 GO:0042562 hormone binding 2/151 86/18367 0.157578586947005 0.387496293704411 CTSH/RXFP1 2 GO:0005243 gap junction channel activity 1/151 21/18367 0.159245052207292 0.387496293704411 GJA1 1 GO:0015216 purine nucleotide transmembrane transporter activity 1/151 21/18367 0.159245052207292 0.387496293704411 SLC35B2 1 GO:0008093 cytoskeletal anchor activity 1/151 22/18367 0.166165034607636 0.389009416886038 EPB41L3 1 GO:0015296 anion:cation symporter activity 1/151 22/18367 0.166165034607636 0.389009416886038 SLC39A14 1 GO:0016881 acid-amino acid ligase activity 1/151 22/18367 0.166165034607636 0.389009416886038 GCLC 1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/151 22/18367 0.166165034607636 0.389009416886038 SNCA 1 GO:0072349 modified amino acid transmembrane transporter activity 1/151 22/18367 0.166165034607636 0.389009416886038 GJA1 1 GO:0019888 protein phosphatase regulator activity 2/151 89/18367 0.166261558997868 0.389009416886038 PPP2R1B/PPP1R15A 2 GO:0003713 transcription coactivator activity 4/151 262/18367 0.169801362981911 0.394721117291065 PPARGC1A/LPIN3/CBFB/BCL9L 4 GO:0003950 NAD+ ADP-ribosyltransferase activity 1/151 23/18367 0.173028434976905 0.394721117291065 PARP9 1 GO:0005158 insulin receptor binding 1/151 23/18367 0.173028434976905 0.394721117291065 IRS2 1 GO:0050750 low-density lipoprotein particle receptor binding 1/151 23/18367 0.173028434976905 0.394721117291065 DKK1 1 GO:0043274 phospholipase binding 1/151 24/18367 0.179835712905301 0.397818395214756 SNCA 1 GO:0043495 protein-membrane adaptor activity 1/151 24/18367 0.179835712905301 0.397818395214756 EPB41L3 1 GO:0050431 transforming growth factor beta binding 1/151 24/18367 0.179835712905301 0.397818395214756 TSKU 1 GO:0070840 dynein complex binding 1/151 24/18367 0.179835712905301 0.397818395214756 SNCA 1 GO:0120014 phospholipid transfer activity 1/151 24/18367 0.179835712905301 0.397818395214756 PRELID3B 1 GO:0016757 glycosyltransferase activity 4/151 270/18367 0.182736656483614 0.401800479617585 B4GALT1/MTAP/PARP9/GALNT15 4 GO:0005160 transforming growth factor beta receptor binding 1/151 25/18367 0.186587324274831 0.40538317476377 SMAD3 1 GO:0035035 histone acetyltransferase binding 1/151 25/18367 0.186587324274831 0.40538317476377 CEBPB 1 GO:0004435 phosphatidylinositol phospholipase C activity 1/151 26/18367 0.193283721289033 0.409959290243798 BDKRB2 1 GO:0008198 ferrous iron binding 1/151 26/18367 0.193283721289033 0.409959290243798 SNCA 1 GO:0097602 cullin family protein binding 1/151 26/18367 0.193283721289033 0.409959290243798 DCUN1D1 1 GO:0015631 tubulin binding 5/151 375/18367 0.196547615399252 0.409959290243798 MX1/PPARGC1A/SNCA/NDRG1/GJA1 5 GO:0004709 MAP kinase kinase kinase activity 1/151 27/18367 0.199925352502455 0.409959290243798 MAP3K4 1 GO:0015215 nucleotide transmembrane transporter activity 1/151 27/18367 0.199925352502455 0.409959290243798 SLC35B2 1 GO:0022884 macromolecule transmembrane transporter activity 1/151 27/18367 0.199925352502455 0.409959290243798 SLC15A4 1 GO:0023026 MHC class II protein complex binding 1/151 27/18367 0.199925352502455 0.409959290243798 PKM 1 GO:0043425 bHLH transcription factor binding 1/151 27/18367 0.199925352502455 0.409959290243798 SMAD3 1 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/151 27/18367 0.199925352502455 0.409959290243798 ATP11A 1 GO:0004629 phospholipase C activity 1/151 28/18367 0.206512662849899 0.41429976904274 BDKRB2 1 GO:0043236 laminin binding 1/151 28/18367 0.206512662849899 0.41429976904274 SHH 1 GO:0070325 lipoprotein particle receptor binding 1/151 28/18367 0.206512662849899 0.41429976904274 DKK1 1 GO:0008238 exopeptidase activity 2/151 103/18367 0.207717418451566 0.41429976904274 CTSH/CNDP2 2 GO:0031490 chromatin DNA binding 2/151 103/18367 0.207717418451566 0.41429976904274 PPARGC1A/SMAD3 2 GO:0140098 catalytic activity, acting on RNA 5/151 386/18367 0.212474763701156 0.418074323610413 DUS1L/DDX41/PCIF1/ALKBH5/MOV10L1 5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/151 29/18367 0.213046093675444 0.418074323610413 PTGR2 1 GO:0035250 UDP-galactosyltransferase activity 1/151 29/18367 0.213046093675444 0.418074323610413 B4GALT1 1 GO:0019902 phosphatase binding 3/151 196/18367 0.218607418613901 0.419665688562628 PPP1R15A/IRS2/SMAD3 3 GO:0016417 S-acyltransferase activity 1/151 30/18367 0.219526082761223 0.419665688562628 MCAT 1 GO:0017147 Wnt-protein binding 1/151 30/18367 0.219526082761223 0.419665688562628 FZD8 1 GO:0022829 wide pore channel activity 1/151 30/18367 0.219526082761223 0.419665688562628 GJA1 1 GO:0019208 phosphatase regulator activity 2/151 107/18367 0.219766754218177 0.419665688562628 PPP2R1B/PPP1R15A 2 GO:0016758 hexosyltransferase activity 3/151 197/18367 0.22075564987404 0.419665688562628 B4GALT1/MTAP/GALNT15 3 GO:0008157 protein phosphatase 1 binding 1/151 31/18367 0.225953064355979 0.421888190344476 PPP1R15A 1 GO:0043015 gamma-tubulin binding 1/151 31/18367 0.225953064355979 0.421888190344476 NDRG1 1 GO:0140318 protein transporter activity 1/151 31/18367 0.225953064355979 0.421888190344476 ATAD1 1 GO:0008378 galactosyltransferase activity 1/151 32/18367 0.232327469203397 0.421888190344476 B4GALT1 1 GO:0015605 organophosphate ester transmembrane transporter activity 1/151 32/18367 0.232327469203397 0.421888190344476 SLC35B2 1 GO:0030515 snoRNA binding 1/151 32/18367 0.232327469203397 0.421888190344476 NOP14 1 GO:0031624 ubiquitin conjugating enzyme binding 1/151 32/18367 0.232327469203397 0.421888190344476 DCUN1D1 1 GO:0048019 receptor antagonist activity 1/151 32/18367 0.232327469203397 0.421888190344476 DKK1 1 GO:0050699 WW domain binding 1/151 32/18367 0.232327469203397 0.421888190344476 PMEPA1 1 GO:0005154 epidermal growth factor receptor binding 1/151 33/18367 0.238649724570197 0.426995830726088 PLSCR1 1 GO:0008200 ion channel inhibitor activity 1/151 33/18367 0.238649724570197 0.426995830726088 SLC30A1 1 GO:0051427 hormone receptor binding 1/151 33/18367 0.238649724570197 0.426995830726088 GH2 1 GO:0008376 acetylgalactosaminyltransferase activity 1/151 34/18367 0.244920254274021 0.429787946202007 GALNT15 1 GO:0016248 channel inhibitor activity 1/151 34/18367 0.244920254274021 0.429787946202007 SLC30A1 1 GO:0030291 protein serine/threonine kinase inhibitor activity 1/151 34/18367 0.244920254274021 0.429787946202007 HEXIM1 1 GO:0043548 phosphatidylinositol 3-kinase binding 1/151 34/18367 0.244920254274021 0.429787946202007 IRS2 1 GO:0023023 MHC protein complex binding 1/151 36/18367 0.2573078148836 0.447225487773877 PKM 1 GO:0042605 peptide antigen binding 1/151 36/18367 0.2573078148836 0.447225487773877 HLA-F 1 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/151 37/18367 0.263425676427028 0.451410196694203 ALDH5A1 1 GO:0042056 chemoattractant activity 1/151 37/18367 0.263425676427028 0.451410196694203 VEGFA 1 GO:0043531 ADP binding 1/151 37/18367 0.263425676427028 0.451410196694203 GCLC 1 GO:0051082 unfolded protein binding 2/151 122/18367 0.265337419693988 0.452561486861242 HSPA1A/HSPA1B 2 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/151 38/18367 0.26949347363704 0.455394064247776 CCNH 1 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/151 38/18367 0.26949347363704 0.455394064247776 DCUN1D1 1 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/151 39/18367 0.275511613496324 0.461292380395221 AK4 1 GO:0032451 demethylase activity 1/151 39/18367 0.275511613496324 0.461292380395221 ALKBH5 1 GO:0005085 guanyl-nucleotide exchange factor activity 3/151 223/18367 0.277843606365435 0.462044130526048 TRIO/SH3BP5/RABGEF1 3 GO:0004175 endopeptidase activity 5/151 430/18367 0.279758226976046 0.462044130526048 CFI/SHH/HTRA3/CTSH/PLAT 5 GO:0046873 metal ion transmembrane transporter activity 5/151 430/18367 0.279758226976046 0.462044130526048 SLC41A2/SLC25A37/SLC30A1/SLC39A14/TRPC4 5 GO:0004177 aminopeptidase activity 1/151 40/18367 0.28148049970115 0.462794515274413 CTSH 1 GO:0140678 molecular function inhibitor activity 2/151 128/18367 0.283613900612825 0.464211092931305 SLC30A1/PARP9 2 GO:0030331 estrogen receptor binding 1/151 41/18367 0.287400532687734 0.466227530804546 PPARGC1A 1 GO:0048487 beta-tubulin binding 1/151 41/18367 0.287400532687734 0.466227530804546 SNCA 1 GO:0015078 proton transmembrane transporter activity 2/151 130/18367 0.289699367285579 0.467877296722284 SLC15A4/SLC15A1 2 GO:0019205 nucleobase-containing compound kinase activity 1/151 42/18367 0.293272109658385 0.469492631689958 AK4 1 GO:0019894 kinesin binding 1/151 42/18367 0.293272109658385 0.469492631689958 SNCA 1 GO:0004180 carboxypeptidase activity 1/151 43/18367 0.299095624607448 0.46954753415471 CNDP2 1 GO:0016504 peptidase activator activity 1/151 43/18367 0.299095624607448 0.46954753415471 CTSH 1 GO:0030544 Hsp70 protein binding 1/151 43/18367 0.299095624607448 0.46954753415471 SNCA 1 GO:0030547 signaling receptor inhibitor activity 1/151 43/18367 0.299095624607448 0.46954753415471 DKK1 1 GO:0001784 phosphotyrosine residue binding 1/151 44/18367 0.30487146834704 0.46954753415471 SOCS3 1 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/151 44/18367 0.30487146834704 0.46954753415471 PRKAA2 1 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/151 44/18367 0.30487146834704 0.46954753415471 ALDH5A1 1 GO:0051879 Hsp90 protein binding 1/151 44/18367 0.30487146834704 0.46954753415471 HIF1A 1 GO:0043177 organic acid binding 2/151 135/18367 0.304884289300456 0.46954753415471 HBG1/GCLC 2 GO:0048156 tau protein binding 1/151 45/18367 0.310600028532577 0.474347323909584 SNCA 1 GO:0140223 general transcription initiation factor activity 1/151 45/18367 0.310600028532577 0.474347323909584 CCNH 1 GO:0015291 secondary active transmembrane transporter activity 3/151 240/18367 0.315945522288707 0.480090465369494 SLC15A4/SLC15A1/SLC39A14 3 GO:0099106 ion channel regulator activity 2/151 139/18367 0.316991238778214 0.480090465369494 GEM/SLC30A1 2 GO:0005044 scavenger receptor activity 1/151 47/18367 0.321916833231421 0.485205841300302 CFI 1 GO:0070851 growth factor receptor binding 2/151 141/18367 0.323027450509516 0.485205841300302 PLSCR1/VEGFA 2 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/151 48/18367 0.327505837499 0.48791685994749 GCLC 1 GO:0120013 lipid transfer activity 1/151 48/18367 0.327505837499 0.48791685994749 PRELID3B 1 GO:0008194 UDP-glycosyltransferase activity 2/151 143/18367 0.329050504717502 0.488225342365399 B4GALT1/GALNT15 2 GO:0043539 protein serine/threonine kinase activator activity 1/151 49/18367 0.333049077770721 0.492157544074143 STK4 1 GO:0016247 channel regulator activity 2/151 145/18367 0.335059218527853 0.493131511139783 GEM/SLC30A1 2 GO:0000993 RNA polymerase II complex binding 1/151 50/18367 0.338546926294393 0.494278512389814 PCIF1 1 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/151 50/18367 0.338546926294393 0.494278512389814 SLC35B2 1 GO:0008528 G protein-coupled peptide receptor activity 2/151 147/18367 0.341052450805037 0.495952767106926 BDKRB2/RXFP1 2 GO:0004601 peroxidase activity 1/151 51/18367 0.343999752310091 0.498253609496759 HBG1 1 GO:0016597 amino acid binding 1/151 52/18367 0.349407922074296 0.502968383416039 GCLC 1 GO:0019903 protein phosphatase binding 2/151 150/18367 0.350010875034723 0.502968383416039 PPP1R15A/IRS2 2 GO:0017069 snRNA binding 1/151 53/18367 0.354771798883839 0.507810614088632 HEXIM1 1 GO:0031267 small GTPase binding 3/151 259/18367 0.358648405551571 0.507880981409815 NDRG1/MLPH/RABGEF1 3 GO:0001653 peptide receptor activity 2/151 153/18367 0.358928451606227 0.507880981409815 BDKRB2/RXFP1 2 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/151 54/18367 0.36009174309966 0.507880981409815 ALKBH5 1 GO:0060090 molecular adaptor activity 4/151 369/18367 0.36038677858943 0.507880981409815 MLPH/EPB41L3/PSMG1/DAB2 4 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/151 55/18367 0.365368112170372 0.512395674281569 HBG1 1 GO:0004386 helicase activity 2/151 156/18367 0.367801826470606 0.512395674281569 DDX41/MOV10L1 2 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/151 156/18367 0.367801826470606 0.512395674281569 PCIF1/NNMT 2 GO:0030374 nuclear receptor coactivator activity 1/151 56/18367 0.370601260655642 0.514332548058211 PPARGC1A 1 GO:0005525 GTP binding 4/151 377/18367 0.375326348915234 0.516690227740368 MX1/IFI44L/GEM/AK4 4 GO:0043175 RNA polymerase core enzyme binding 1/151 57/18367 0.375791540249384 0.516690227740368 PCIF1 1 GO:0022853 active ion transmembrane transporter activity 3/151 267/18367 0.3765468509012 0.516690227740368 SLC15A4/SLC15A1/SLC39A14 3 GO:0005126 cytokine receptor binding 3/151 271/18367 0.385461104691448 0.524975011986487 GH2/VEGFA/SMAD3 3 GO:0008017 microtubule binding 3/151 271/18367 0.385461104691448 0.524975011986487 MX1/SNCA/NDRG1 3 GO:0005507 copper ion binding 1/151 61/18367 0.396130904569189 0.537501041515814 SNCA 1 GO:0003823 antigen binding 2/151 171/18367 0.411400935859912 0.555938816750256 IGKC/HLA-F 2 GO:0019001 guanyl nucleotide binding 4/151 398/18367 0.41436896212939 0.555938816750256 MX1/IFI44L/GEM/AK4 4 GO:0032561 guanyl ribonucleotide binding 4/151 398/18367 0.41436896212939 0.555938816750256 MX1/IFI44L/GEM/AK4 4 GO:0008173 RNA methyltransferase activity 1/151 65/18367 0.415811772528273 0.555938816750256 PCIF1 1 GO:0002039 p53 binding 1/151 66/18367 0.420631596719522 0.560330411688414 HIF1A 1 GO:0051020 GTPase binding 3/151 291/18367 0.429528976930792 0.570102096653596 NDRG1/MLPH/RABGEF1 3 GO:0005518 collagen binding 1/151 69/18367 0.43485532570794 0.572026280421341 SMAD3 1 GO:0001664 G protein-coupled receptor binding 3/151 295/18367 0.438217355218456 0.572026280421341 BDKRB2/HSPA1A/HSPA1B 3 GO:0001098 basal transcription machinery binding 1/151 70/18367 0.439519051023172 0.572026280421341 PCIF1 1 GO:0001099 basal RNA polymerase II transcription machinery binding 1/151 70/18367 0.439519051023172 0.572026280421341 PCIF1 1 GO:0004857 enzyme inhibitor activity 1/151 70/18367 0.439519051023172 0.572026280421341 PARP9 1 GO:0030674 protein-macromolecule adaptor activity 3/151 296/18367 0.440381876159991 0.572026280421341 MLPH/EPB41L3/DAB2 3 GO:0008235 metalloexopeptidase activity 1/151 72/18367 0.448732112448555 0.576473711161786 CNDP2 1 GO:0030276 clathrin binding 1/151 72/18367 0.448732112448555 0.576473711161786 DAB2 1 GO:0035064 methylated histone binding 1/151 73/18367 0.453282068776528 0.576473711161786 CBX4 1 GO:0070063 RNA polymerase binding 1/151 73/18367 0.453282068776528 0.576473711161786 PCIF1 1 GO:0140034 methylation-dependent protein binding 1/151 73/18367 0.453282068776528 0.576473711161786 CBX4 1 GO:0140104 molecular carrier activity 1/151 73/18367 0.453282068776528 0.576473711161786 HBG1 1 GO:0017022 myosin binding 1/151 74/18367 0.457794718148712 0.58019122265375 MLPH 1 GO:0008022 protein C-terminus binding 2/151 189/18367 0.461705469186374 0.581823044895388 IFT46/DAB2 2 GO:0019003 GDP binding 1/151 75/18367 0.462270364437432 0.581823044895388 GEM 1 GO:0030971 receptor tyrosine kinase binding 1/151 78/18367 0.47547828676511 0.595831337089209 TOB1 1 GO:0001217 DNA-binding transcription repressor activity 3/151 313/18367 0.476665069671367 0.595831337089209 SMAD3/MYC/CEBPB 3 GO:0034987 immunoglobulin receptor binding 1/151 79/18367 0.479808910566218 0.596651730231632 IGKC 1 GO:0016829 lyase activity 2/151 196/18367 0.48059070873452 0.596651730231632 ALAD/CA12 2 GO:0050660 flavin adenine dinucleotide binding 1/151 85/18367 0.50505677689254 0.624900757850091 DUS1L 1 GO:0046982 protein heterodimerization activity 3/151 328/18367 0.507768784828988 0.626133805616827 BDKRB2/HIF1A/CEBPB 3 GO:0003727 single-stranded RNA binding 1/151 87/18367 0.513199191454941 0.63069934303385 CBX4 1 GO:0048306 calcium-dependent protein binding 1/151 88/18367 0.517220357871259 0.632030272440865 S100A16 1 GO:0008081 phosphoric diester hydrolase activity 1/151 89/18367 0.521208526040275 0.632030272440865 BDKRB2 1 GO:0043178 alcohol binding 1/151 89/18367 0.521208526040275 0.632030272440865 TRPC4 1 GO:0051117 ATPase binding 1/151 89/18367 0.521208526040275 0.632030272440865 PIH1D1 1 GO:0008168 methyltransferase activity 2/151 214/18367 0.527248391100396 0.637237293879618 PCIF1/NNMT 2 GO:0043130 ubiquitin binding 1/151 92/18367 0.532977720166229 0.639923907436426 SMAD3 1 GO:0051213 dioxygenase activity 1/151 92/18367 0.532977720166229 0.639923907436426 ALKBH5 1 GO:0008170 N-methyltransferase activity 1/151 97/18367 0.551957761162132 0.660539615816978 NNMT 1 GO:0016741 transferase activity, transferring one-carbon groups 2/151 225/18367 0.554347685323794 0.660639052680884 PCIF1/NNMT 2 GO:0004867 serine-type endopeptidase inhibitor activity 1/151 98/18367 0.555660792254881 0.660639052680884 SPOCK1 1 GO:0005539 glycosaminoglycan binding 2/151 230/18367 0.566300810060224 0.669271146632238 SHH/VEGFA 2 GO:0030295 protein kinase activator activity 1/151 101/18367 0.566588450162634 0.669271146632238 STK4 1 GO:0048018 receptor ligand activity 4/151 487/18367 0.570697117337539 0.671949831703876 GH2/SHH/VEGFA/DKK1 4 GO:0005200 structural constituent of cytoskeleton 1/151 103/18367 0.573724814145355 0.673342627533937 EPB41L3 1 GO:0004620 phospholipase activity 1/151 104/18367 0.577249099792752 0.675307440462674 BDKRB2 1 GO:1990782 protein tyrosine kinase binding 1/151 105/18367 0.580744439327948 0.677225943625243 TOB1 1 GO:0030546 signaling receptor activator activity 4/151 495/18367 0.583638255713428 0.67843300425287 GH2/SHH/VEGFA/DKK1 4 GO:0019209 kinase activator activity 1/151 107/18367 0.587649222835124 0.680926877253398 STK4 1 GO:0000149 SNARE binding 1/151 110/18367 0.597795144665558 0.690491227224457 SNCA 1 GO:0004197 cysteine-type endopeptidase activity 1/151 119/18367 0.626768689952147 0.719404313938785 CTSH 1 GO:0005262 calcium channel activity 1/151 119/18367 0.626768689952147 0.719404313938785 TRPC4 1 GO:0005179 hormone activity 1/151 122/18367 0.63595806362414 0.72766361511853 GH2 1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/151 124/18367 0.64195908884995 0.729428478572173 PTGR2 1 GO:0140101 catalytic activity, acting on a tRNA 1/151 124/18367 0.64195908884995 0.729428478572173 DUS1L 1 GO:1901681 sulfur compound binding 2/151 265/18367 0.643495808493807 0.729428478572173 PCIF1/VEGFA 2 GO:0022804 active transmembrane transporter activity 3/151 406/18367 0.652158469722085 0.736959261450653 SLC15A4/SLC15A1/SLC39A14 3 GO:0016298 lipase activity 1/151 129/18367 0.656535171422817 0.739615239411507 BDKRB2 1 GO:0044325 transmembrane transporter binding 1/151 133/18367 0.667770351262067 0.749957471417398 CHERP 1 GO:0002020 protease binding 1/151 135/18367 0.673250259160601 0.751487292335228 BDKRB2 1 GO:0015085 calcium ion transmembrane transporter activity 1/151 135/18367 0.673250259160601 0.751487292335228 TRPC4 1 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/151 136/18367 0.675956446680717 0.752207631214822 PTGR2 1 GO:0019955 cytokine binding 1/151 139/18367 0.683942140799973 0.756481458763606 TSKU 1 GO:0020037 heme binding 1/151 139/18367 0.683942140799973 0.756481458763606 HBG1 1 GO:0140375 immune receptor activity 1/151 144/18367 0.696819479551456 0.768396102828645 CTSH 1 GO:0003779 actin binding 3/151 440/18367 0.704922909799293 0.774990548423922 SNCA/MLPH/EPB41L3 3 GO:0046906 tetrapyrrole binding 1/151 149/18367 0.709175482510563 0.777324477826893 HBG1 1 GO:0005506 iron ion binding 1/151 151/18367 0.713976635728556 0.780243928266236 SNCA 1 GO:0015103 inorganic anion transmembrane transporter activity 1/151 152/18367 0.716347602351578 0.780498133905451 SLC39A14 1 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/151 310/18367 0.726418981493748 0.789115857872672 MYC/CEBPB 2 GO:0140030 modification-dependent protein binding 1/151 160/18367 0.734625695568539 0.792618223485649 CBX4 1 GO:0005096 GTPase activator activity 3/151 462/18367 0.735706253819495 0.792618223485649 TRIO/SH3BP5/RABGEF1 3 GO:0061659 ubiquitin-like protein ligase activity 2/151 316/18367 0.73615774729215 0.792618223485649 CBX4/PIAS2 2 GO:0005543 phospholipid binding 3/151 466/18367 0.741024922322522 0.795512048963884 SNCA/MYOF/PACSIN2 3 GO:0016874 ligase activity 1/151 165/18367 0.745450268656207 0.797836594947525 GCLC 1 GO:0008201 heparin binding 1/151 166/18367 0.747561960197407 0.797836594947525 VEGFA 1 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/151 170/18367 0.755836114387645 0.804315398692392 ALKBH5 1 GO:0005201 extracellular matrix structural constituent 1/151 172/18367 0.759871590749678 0.806259100650094 SRPX 1 GO:0031406 carboxylic acid binding 1/151 176/18367 0.767744835840717 0.806339074821751 GCLC 1 GO:0003924 GTPase activity 2/151 337/18367 0.767960330242891 0.806339074821751 MX1/GEM 2 GO:0030695 GTPase regulator activity 3/151 488/18367 0.768783556268409 0.806339074821751 TRIO/SH3BP5/RABGEF1 3 GO:0060589 nucleoside-triphosphatase regulator activity 3/151 488/18367 0.768783556268409 0.806339074821751 TRIO/SH3BP5/RABGEF1 3 GO:0008234 cysteine-type peptidase activity 1/151 190/18367 0.793335150458084 0.827335228334859 CTSH 1 GO:0008237 metallopeptidase activity 1/151 190/18367 0.793335150458084 0.827335228334859 CNDP2 1 GO:0042578 phosphoric ester hydrolase activity 2/151 366/18367 0.806402279566989 0.838566473053991 BDKRB2/LPIN3 2 GO:0005516 calmodulin binding 1/151 201/18367 0.811459628377651 0.84142830783478 GEM 1 GO:0004518 nuclease activity 1/151 210/18367 0.825107271972408 0.853156244390733 PLSCR1 1 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/151 222/18367 0.841789124222159 0.867946413392904 MCAT 1 GO:0005125 cytokine activity 1/151 235/18367 0.858081070117328 0.882252367867112 VEGFA 1 GO:0016746 acyltransferase activity 1/151 250/18367 0.874818210289756 0.896934400999328 MCAT 1 GO:0019787 ubiquitin-like protein transferase activity 2/151 458/18367 0.893634804260822 0.912505707146617 CBX4/PIAS2 2 GO:0030246 carbohydrate binding 1/151 271/18367 0.895005597694491 0.912505707146617 GALNT15 1 GO:0016791 phosphatase activity 1/151 275/18367 0.898466715796352 0.913482872606318 LPIN3 1 GO:0015267 channel activity 2/151 480/18367 0.908256859781872 0.918945594171735 GJA1/TRPC4 2 GO:0022803 passive transmembrane transporter activity 2/151 481/18367 0.908874957523278 0.918945594171735 GJA1/TRPC4 2 GO:0042277 peptide binding 1/151 321/18367 0.930982048939701 0.938697369787268 HLA-F 1 GO:0005261 cation channel activity 1/151 335/18367 0.938644419533277 0.943816014131256 TRPC4 1 GO:0033218 amide binding 1/151 400/18367 0.964515082712455 0.967164849423204 HLA-F 1 GO:0005216 ion channel activity 1/151 432/18367 0.972919890127031 0.972919890127031 TRPC4 1