ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0030546 signaling receptor activator activity 12/123 495/18367 0.000123089856788914 0.0396349338860303 CCL21/SEMA3D/SEMA3A/GAS6/LGALS3/CCL4/IL7/CCL14/TGFB2/EFNA5/METRNL/TYMP 12 GO:0048018 receptor ligand activity 11/123 487/18367 0.000433908023740843 0.0698591918222758 CCL21/SEMA3D/SEMA3A/GAS6/LGALS3/CCL4/IL7/CCL14/TGFB2/METRNL/TYMP 11 GO:0048020 CCR chemokine receptor binding 3/123 48/18367 0.00406961682804973 0.298875080217458 CCL21/CCL4/CCL14 3 GO:0008009 chemokine activity 3/123 49/18367 0.00431406245071549 0.298875080217458 CCL21/CCL4/CCL14 3 GO:0005201 extracellular matrix structural constituent 5/123 172/18367 0.0060424308682797 0.298875080217458 IGFBP7/NID2/SPARC/COL15A1/COL3A1 5 GO:0030296 protein tyrosine kinase activator activity 2/123 20/18367 0.0078109511903607 0.298875080217458 GAS6/EFNA5 2 GO:0005540 hyaluronic acid binding 2/123 22/18367 0.00941402324968504 0.298875080217458 LYVE1/LAYN 2 GO:0005126 cytokine receptor binding 6/123 271/18367 0.00987266814672561 0.298875080217458 CCL21/CCL4/IL7/CCL14/TGFB2/EFNA5 6 GO:0030246 carbohydrate binding 6/123 271/18367 0.00987266814672561 0.298875080217458 EGLN3/MRC1/GALNT18/LGALS3/LAYN/ASGR1 6 GO:0030215 semaphorin receptor binding 2/123 23/18367 0.0102657761174133 0.298875080217458 SEMA3D/SEMA3A 2 GO:0019902 phosphatase binding 5/123 196/18367 0.0103106896220683 0.298875080217458 FLT4/SIRPA/PDLIM4/LGALS3/ELL 5 GO:0005518 collagen binding 3/123 69/18367 0.0111382017472345 0.298875080217458 NID2/SPARC/LOX 3 GO:0042379 chemokine receptor binding 3/123 72/18367 0.0124967969525196 0.301141542939112 CCL21/CCL4/CCL14 3 GO:0045499 chemorepellent activity 2/123 27/18367 0.0139965282902845 0.301141542939112 SEMA3D/SEMA3A 2 GO:0019838 growth factor binding 4/123 141/18367 0.0149586731939507 0.301141542939112 FLT4/IGFBP7/A2M/COL3A1 4 GO:0038024 cargo receptor activity 3/123 77/18367 0.0149635549286515 0.301141542939112 MRC1/CD163L1/ASGR1 3 GO:0019903 protein phosphatase binding 4/123 150/18367 0.0183546461927858 0.347658592592766 FLT4/SIRPA/PDLIM4/LGALS3 4 GO:0019956 chemokine binding 2/123 33/18367 0.0205135216092991 0.349392909917502 PDPN/A2M 2 GO:0005125 cytokine activity 5/123 235/18367 0.0210189807771213 0.349392909917502 CCL21/CCL4/IL7/CCL14/TGFB2 5 GO:0008376 acetylgalactosaminyltransferase activity 2/123 34/18367 0.0217014229762423 0.349392909917502 GALNT18/CSGALNACT1 2 GO:0000175 3'-5'-exoribonuclease activity 2/123 35/18367 0.0229172434781395 0.351397733331472 REXO2/ISG20 2 GO:0072341 modified amino acid binding 3/123 93/18367 0.0245858700401242 0.359847734223636 GAS6/GSTM3/MTHFR 3 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters 2/123 38/18367 0.0267280338989026 0.364563807475666 REXO2/ISG20 2 GO:0005504 fatty acid binding 2/123 39/18367 0.028051366405255 0.364563807475666 APOC1/FABP4 2 GO:0004532 exoribonuclease activity 2/123 40/18367 0.0294005570063244 0.364563807475666 REXO2/ISG20 2 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/123 41/18367 0.0307752060995395 0.364563807475666 COL15A1/COL3A1 2 GO:0008307 structural constituent of muscle 2/123 42/18367 0.0321749181976803 0.364563807475666 SYNM/SMTN 2 GO:0004866 endopeptidase inhibitor activity 4/123 180/18367 0.032947481879767 0.364563807475666 SERPING1/GAS6/A2M/GAPDH 4 GO:1990782 protein tyrosine kinase binding 3/123 105/18367 0.0335411052021803 0.364563807475666 ANGPT2/SIRPA/GAS6 3 GO:0030414 peptidase inhibitor activity 4/123 187/18367 0.0371030512534666 0.364563807475666 SERPING1/GAS6/A2M/GAPDH 4 GO:0004864 protein phosphatase inhibitor activity 2/123 46/18367 0.038016628899118 0.364563807475666 LGALS3/PPP1R2 2 GO:0005272 sodium channel activity 2/123 46/18367 0.038016628899118 0.364563807475666 SCN3B/SCNN1B 2 GO:0061135 endopeptidase regulator activity 4/123 194/18367 0.0415476608343305 0.364563807475666 SERPING1/GAS6/A2M/GAPDH 4 GO:0019212 phosphatase inhibitor activity 2/123 49/18367 0.0426422936134192 0.364563807475666 LGALS3/PPP1R2 2 GO:0016758 hexosyltransferase activity 4/123 197/18367 0.0435411321659712 0.364563807475666 GALNT18/TMTC1/TYMP/CSGALNACT1 4 GO:0050661 NADP binding 2/123 53/18367 0.049116811717718 0.364563807475666 GAPDH/MTHFR 2 GO:0008408 3'-5' exonuclease activity 2/123 54/18367 0.0507878809776935 0.364563807475666 REXO2/ISG20 2 GO:0050840 extracellular matrix binding 2/123 56/18367 0.0541905178674565 0.364563807475666 SPARC/LGALS3 2 GO:0051287 NAD binding 2/123 56/18367 0.0541905178674565 0.364563807475666 GAPDH/NDUFS2 2 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/123 59/18367 0.0594406493934893 0.364563807475666 REXO2/ISG20 2 GO:0005384 manganese ion transmembrane transporter activity 1/123 10/18367 0.0650008855048538 0.364563807475666 SLC39A14 1 GO:0015173 aromatic amino acid transmembrane transporter activity 1/123 10/18367 0.0650008855048538 0.364563807475666 SLC7A1 1 GO:0016803 ether hydrolase activity 1/123 10/18367 0.0650008855048538 0.364563807475666 EPHX1 1 GO:0034511 U3 snoRNA binding 1/123 10/18367 0.0650008855048538 0.364563807475666 ISG20 1 GO:0050786 RAGE receptor binding 1/123 10/18367 0.0650008855048538 0.364563807475666 S100A4 1 GO:0061134 peptidase regulator activity 4/123 230/18367 0.0689525579435018 0.364563807475666 SERPING1/GAS6/A2M/GAPDH 4 GO:0016801 hydrolase activity, acting on ether bonds 1/123 11/18367 0.0712657921389938 0.364563807475666 EPHX1 1 GO:0043295 glutathione binding 1/123 11/18367 0.0712657921389938 0.364563807475666 GSTM3 1 GO:0048407 platelet-derived growth factor binding 1/123 11/18367 0.0712657921389938 0.364563807475666 COL3A1 1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/123 11/18367 0.0712657921389938 0.364563807475666 SIRPA 1 GO:1901474 azole transmembrane transporter activity 1/123 11/18367 0.0712657921389938 0.364563807475666 SLC7A1 1 GO:0005178 integrin binding 3/123 144/18367 0.0725152855197003 0.364563807475666 CD9/ISG15/COL3A1 3 GO:0051536 iron-sulfur cluster binding 2/123 68/18367 0.0761616517427955 0.364563807475666 CISD1/NDUFS2 2 GO:0051540 metal cluster binding 2/123 68/18367 0.0761616517427955 0.364563807475666 CISD1/NDUFS2 2 GO:0003924 GTPase activity 5/123 337/18367 0.0762894381584453 0.364563807475666 RGS16/ARF5/MX1/MX2/ARL4A 5 GO:0005095 GTPase inhibitor activity 1/123 12/18367 0.0774890601476501 0.364563807475666 CPEB2 1 GO:0005165 neurotrophin receptor binding 1/123 12/18367 0.0774890601476501 0.364563807475666 EFNA5 1 GO:0008296 3'-5'-exodeoxyribonuclease activity 1/123 12/18367 0.0774890601476501 0.364563807475666 ISG20 1 GO:0015280 ligand-gated sodium channel activity 1/123 12/18367 0.0774890601476501 0.364563807475666 SCNN1B 1 GO:0017166 vinculin binding 1/123 12/18367 0.0774890601476501 0.364563807475666 SYNM 1 GO:0031543 peptidyl-proline dioxygenase activity 1/123 12/18367 0.0774890601476501 0.364563807475666 EGLN3 1 GO:0070410 co-SMAD binding 1/123 12/18367 0.0774890601476501 0.364563807475666 SMAD1 1 GO:1900750 oligopeptide binding 1/123 12/18367 0.0774890601476501 0.364563807475666 GSTM3 1 GO:0048029 monosaccharide binding 2/123 71/18367 0.0820309164515917 0.364563807475666 EGLN3/MRC1 2 GO:0002161 aminoacyl-tRNA editing activity 1/123 13/18367 0.0836709640213549 0.364563807475666 DTD1 1 GO:0004859 phospholipase inhibitor activity 1/123 13/18367 0.0836709640213549 0.364563807475666 APOC1 1 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/123 13/18367 0.0836709640213549 0.364563807475666 PPP1R2 1 GO:0008179 adenylate cyclase binding 1/123 13/18367 0.0836709640213549 0.364563807475666 AKAP12 1 GO:0008494 translation activator activity 1/123 13/18367 0.0836709640213549 0.364563807475666 PABPC1 1 GO:0031386 protein tag 1/123 13/18367 0.0836709640213549 0.364563807475666 ISG15 1 GO:0042301 phosphate ion binding 1/123 13/18367 0.0836709640213549 0.364563807475666 PDE2A 1 GO:0140299 small molecule sensor activity 1/123 13/18367 0.0836709640213549 0.364563807475666 NDUFS2 1 GO:0033293 monocarboxylic acid binding 2/123 73/18367 0.0860189515586012 0.364563807475666 APOC1/FABP4 2 GO:0036041 long-chain fatty acid binding 1/123 14/18367 0.0898117764559937 0.364563807475666 FABP4 1 GO:0043023 ribosomal large subunit binding 1/123 14/18367 0.0898117764559937 0.364563807475666 CPEB2 1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/123 14/18367 0.0898117764559937 0.364563807475666 PDE2A 1 GO:0070411 I-SMAD binding 1/123 14/18367 0.0898117764559937 0.364563807475666 SMAD1 1 GO:0001618 virus receptor activity 2/123 76/18367 0.0921081307269373 0.364563807475666 MRC1/CD55 2 GO:0140272 exogenous protein binding 2/123 77/18367 0.0941653194148916 0.364563807475666 MRC1/CD55 2 GO:0008083 growth factor activity 3/123 162/18367 0.0951308763866627 0.364563807475666 IL7/TGFB2/TYMP 3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/123 15/18367 0.095911768364451 0.364563807475666 PDE2A 1 GO:0019215 intermediate filament binding 1/123 15/18367 0.095911768364451 0.364563807475666 SYNM 1 GO:0030553 cGMP binding 1/123 15/18367 0.095911768364451 0.364563807475666 PDE2A 1 GO:0051371 muscle alpha-actinin binding 1/123 15/18367 0.095911768364451 0.364563807475666 PDLIM4 1 GO:0030971 receptor tyrosine kinase binding 2/123 78/18367 0.0962357876876758 0.364563807475666 ANGPT2/GAS6 2 GO:0004527 exonuclease activity 2/123 80/18367 0.10041549990559 0.364830325133207 REXO2/ISG20 2 GO:0000900 translation repressor activity, mRNA regulatory element binding 1/123 16/18367 0.101971208888163 0.364830325133207 CPEB2 1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/123 16/18367 0.101971208888163 0.364830325133207 LOX 1 GO:0019841 retinol binding 1/123 16/18367 0.101971208888163 0.364830325133207 RBP1 1 GO:0035173 histone kinase activity 1/123 16/18367 0.101971208888163 0.364830325133207 PRKAA2 1 GO:0016757 glycosyltransferase activity 4/123 270/18367 0.107932047584724 0.36603050170077 GALNT18/TMTC1/TYMP/CSGALNACT1 4 GO:0005324 long-chain fatty acid transporter activity 1/123 17/18367 0.107990365408612 0.36603050170077 FABP4 1 GO:0008381 mechanosensitive ion channel activity 1/123 17/18367 0.107990365408612 0.36603050170077 PIEZO2 1 GO:0015174 basic amino acid transmembrane transporter activity 1/123 17/18367 0.107990365408612 0.36603050170077 SLC7A1 1 GO:0043024 ribosomal small subunit binding 1/123 17/18367 0.107990365408612 0.36603050170077 CPEB2 1 GO:0048038 quinone binding 1/123 18/18367 0.113969503558734 0.367720587518406 NDUFS2 1 GO:0055102 lipase inhibitor activity 1/123 18/18367 0.113969503558734 0.367720587518406 APOC1 1 GO:0031406 carboxylic acid binding 3/123 176/18367 0.114466058830381 0.367720587518406 EGLN3/APOC1/FABP4 3 GO:0048306 calcium-dependent protein binding 2/123 88/18367 0.117613642363179 0.367720587518406 A2M/S100A4 2 GO:0019888 protein phosphatase regulator activity 2/123 89/18367 0.119813226604157 0.367720587518406 LGALS3/PPP1R2 2 GO:0043178 alcohol binding 2/123 89/18367 0.119813226604157 0.367720587518406 RBP1/OSBPL1A 2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/123 19/18367 0.119908887234263 0.367720587518406 GALNT18 1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/123 19/18367 0.119908887234263 0.367720587518406 MTHFR 1 GO:0016918 retinal binding 1/123 19/18367 0.119908887234263 0.367720587518406 RBP1 1 GO:0035615 clathrin adaptor activity 1/123 19/18367 0.119908887234263 0.367720587518406 STON2 1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/123 20/18367 0.125808778604995 0.371655290924847 LOX 1 GO:0030506 ankyrin binding 1/123 20/18367 0.125808778604995 0.371655290924847 FLNC 1 GO:0031418 L-ascorbic acid binding 1/123 20/18367 0.125808778604995 0.371655290924847 EGLN3 1 GO:0140312 cargo adaptor activity 1/123 20/18367 0.125808778604995 0.371655290924847 STON2 1 GO:0019001 guanyl nucleotide binding 5/123 398/18367 0.129155086270322 0.374666106117509 PDE2A/ARF5/MX1/MX2/ARL4A 5 GO:0032561 guanyl ribonucleotide binding 5/123 398/18367 0.129155086270322 0.374666106117509 PDE2A/ARF5/MX1/MX2/ARL4A 5 GO:0005385 zinc ion transmembrane transporter activity 1/123 21/18367 0.131669438125984 0.375075272911162 SLC39A14 1 GO:0005537 mannose binding 1/123 22/18367 0.137491124548665 0.375075272911162 MRC1 1 GO:0015296 anion:cation symporter activity 1/123 22/18367 0.137491124548665 0.375075272911162 SLC39A14 1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/123 22/18367 0.137491124548665 0.375075272911162 GAS6 1 GO:0004867 serine-type endopeptidase inhibitor activity 2/123 98/18367 0.140044135902466 0.375075272911162 SERPING1/A2M 2 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/123 23/18367 0.143274094931903 0.375075272911162 PDE2A 1 GO:0004529 exodeoxyribonuclease activity 1/123 23/18367 0.143274094931903 0.375075272911162 ISG20 1 GO:0005248 voltage-gated sodium channel activity 1/123 23/18367 0.143274094931903 0.375075272911162 SCN3B 1 GO:0008143 poly(A) binding 1/123 23/18367 0.143274094931903 0.375075272911162 PABPC1 1 GO:0016895 exodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/123 23/18367 0.143274094931903 0.375075272911162 ISG20 1 GO:0019865 immunoglobulin binding 1/123 23/18367 0.143274094931903 0.375075272911162 LGALS3 1 GO:0030552 cAMP binding 1/123 23/18367 0.143274094931903 0.375075272911162 PDE2A 1 GO:0030295 protein kinase activator activity 2/123 101/18367 0.146944344113585 0.377826698411486 GAS6/EFNA5 2 GO:0000030 mannosyltransferase activity 1/123 24/18367 0.149018604652977 0.377826698411486 TMTC1 1 GO:0016769 transferase activity, transferring nitrogenous groups 1/123 24/18367 0.149018604652977 0.377826698411486 GAPDH 1 GO:0051537 2 iron, 2 sulfur cluster binding 1/123 24/18367 0.149018604652977 0.377826698411486 CISD1 1 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/123 25/18367 0.154724907418484 0.378280910222052 PDE2A 1 GO:0005160 transforming growth factor beta receptor binding 1/123 25/18367 0.154724907418484 0.378280910222052 TGFB2 1 GO:0008266 poly(U) RNA binding 1/123 25/18367 0.154724907418484 0.378280910222052 PABPC1 1 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/123 25/18367 0.154724907418484 0.378280910222052 CPEB2 1 GO:0019887 protein kinase regulator activity 3/123 204/18367 0.157014794911577 0.378280910222052 CCND2/GAS6/EFNA5 3 GO:0004364 glutathione transferase activity 1/123 26/18367 0.16039325527518 0.378280910222052 GSTM3 1 GO:0008198 ferrous iron binding 1/123 26/18367 0.16039325527518 0.378280910222052 EGLN3 1 GO:0030371 translation repressor activity 1/123 26/18367 0.16039325527518 0.378280910222052 CPEB2 1 GO:0019208 phosphatase regulator activity 2/123 107/18367 0.160945604659693 0.378280910222052 LGALS3/PPP1R2 2 GO:0019209 kinase activator activity 2/123 107/18367 0.160945604659693 0.378280910222052 GAS6/EFNA5 2 GO:0090079 translation regulator activity, nucleic acid binding 2/123 108/18367 0.163302865281072 0.381040018989169 CPEB2/PABPC1 2 GO:0051393 alpha-actinin binding 1/123 27/18367 0.166023898620753 0.381108288007412 PDLIM4 1 GO:0008047 enzyme activator activity 2/123 110/18367 0.168035988795414 0.381108288007412 NUPR1/APOC1 2 GO:0008187 poly-pyrimidine tract binding 1/123 28/18367 0.171617086214518 0.381108288007412 PABPC1 1 GO:0043236 laminin binding 1/123 28/18367 0.171617086214518 0.381108288007412 LGALS3 1 GO:0046875 ephrin receptor binding 1/123 28/18367 0.171617086214518 0.381108288007412 EFNA5 1 GO:0070325 lipoprotein particle receptor binding 1/123 28/18367 0.171617086214518 0.381108288007412 RELN 1 GO:1990756 ubiquitin ligase-substrate adaptor activity 1/123 28/18367 0.171617086214518 0.381108288007412 SPSB1 1 GO:0005520 insulin-like growth factor binding 1/123 29/18367 0.177173065188051 0.385471128314543 IGFBP7 1 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/123 29/18367 0.177173065188051 0.385471128314543 MTHFR 1 GO:0070717 poly-purine tract binding 1/123 29/18367 0.177173065188051 0.385471128314543 PABPC1 1 GO:0004540 ribonuclease activity 2/123 116/18367 0.182370958378581 0.392179000666344 REXO2/ISG20 2 GO:0070566 adenylyltransferase activity 1/123 30/18367 0.18269208105575 0.392179000666344 OAS1 1 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 5/123 450/18367 0.18435605834673 0.393130137666537 MAF/HOXD8/EPAS1/SMAD1/KLF6 5 GO:0005261 cation channel activity 4/123 335/18367 0.187326236077869 0.39602712174874 GPM6A/SCN3B/PIEZO2/SCNN1B 4 GO:0031210 phosphatidylcholine binding 1/123 31/18367 0.188174377725333 0.39602712174874 APOC1 1 GO:0001216 DNA-binding transcription activator activity 5/123 456/18367 0.191228081689307 0.397106392341785 MAF/HOXD8/EPAS1/SMAD1/KLF6 5 GO:0001223 transcription coactivator binding 1/123 32/18367 0.193620197508262 0.397106392341785 EPAS1 1 GO:0030515 snoRNA binding 1/123 32/18367 0.193620197508262 0.397106392341785 ISG20 1 GO:0050699 WW domain binding 1/123 32/18367 0.193620197508262 0.397106392341785 SCNN1B 1 GO:0008200 ion channel inhibitor activity 1/123 33/18367 0.199029781130104 0.403066600779205 SCN3B 1 GO:0051427 hormone receptor binding 1/123 33/18367 0.199029781130104 0.403066600779205 FABP4 1 GO:0015020 glucuronosyltransferase activity 1/123 34/18367 0.204403367740828 0.408129119168323 CSGALNACT1 1 GO:0016248 channel inhibitor activity 1/123 34/18367 0.204403367740828 0.408129119168323 SCN3B 1 GO:0019207 kinase regulator activity 3/123 233/18367 0.205332041320709 0.408129119168323 CCND2/GAS6/EFNA5 3 GO:0140678 molecular function inhibitor activity 2/123 128/18367 0.211526818968266 0.412441775434716 SCN3B/APOC1 2 GO:0015248 sterol transporter activity 1/123 36/18367 0.215043498712075 0.412441775434716 OSBPL1A 1 GO:0042805 actinin binding 1/123 36/18367 0.215043498712075 0.412441775434716 PDLIM4 1 GO:0097718 disordered domain specific binding 1/123 36/18367 0.215043498712075 0.412441775434716 GAPDH 1 GO:0017124 SH3 domain binding 2/123 130/18367 0.21643403871006 0.412441775434716 SIRPA/SH3BP2 2 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/123 37/18367 0.220310513586246 0.412441775434716 GAPDH 1 GO:0030551 cyclic nucleotide binding 1/123 37/18367 0.220310513586246 0.412441775434716 PDE2A 1 GO:0042056 chemoattractant activity 1/123 37/18367 0.220310513586246 0.412441775434716 LGALS3 1 GO:0046915 transition metal ion transmembrane transporter activity 1/123 37/18367 0.220310513586246 0.412441775434716 SLC39A14 1 GO:0071949 FAD binding 1/123 37/18367 0.220310513586246 0.412441775434716 MTHFR 1 GO:0044325 transmembrane transporter binding 2/123 133/18367 0.223814134623361 0.412767518951937 SCN3B/FHL1 2 GO:0005501 retinoid binding 1/123 38/18367 0.225542472496714 0.412767518951937 RBP1 1 GO:0019840 isoprenoid binding 1/123 38/18367 0.225542472496714 0.412767518951937 RBP1 1 GO:0002020 protease binding 2/123 135/18367 0.228745387009944 0.412767518951937 A2M/COL3A1 2 GO:0030695 GTPase regulator activity 5/123 488/18367 0.229329456446897 0.412767518951937 RGS16/SIRPA/RAB3IL1/RPGR/CPEB2 5 GO:0060589 nucleoside-triphosphatase regulator activity 5/123 488/18367 0.229329456446897 0.412767518951937 RGS16/SIRPA/RAB3IL1/RPGR/CPEB2 5 GO:0019825 oxygen binding 1/123 39/18367 0.230739606867542 0.412767518951937 NDUFS2 1 GO:0050997 quaternary ammonium group binding 1/123 39/18367 0.230739606867542 0.412767518951937 APOC1 1 GO:0017080 sodium channel regulator activity 1/123 40/18367 0.235902146607573 0.417365336305706 SCN3B 1 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/123 40/18367 0.235902146607573 0.417365336305706 GAS6 1 GO:0019955 cytokine binding 2/123 139/18367 0.238629807434405 0.419884142043052 PDPN/A2M 2 GO:0045182 translation regulator activity 2/123 140/18367 0.241104703225718 0.421933230645006 CPEB2/PABPC1 2 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/123 42/18367 0.246124354313508 0.42407490248448 NDUFS2 1 GO:0051539 4 iron, 4 sulfur cluster binding 1/123 42/18367 0.246124354313508 0.42407490248448 NDUFS2 1 GO:0005525 GTP binding 4/123 377/18367 0.246279524113658 0.42407490248448 ARF5/MX1/MX2/ARL4A 4 GO:0008194 UDP-glycosyltransferase activity 2/123 143/18367 0.248536428758976 0.425684734363778 GALNT18/CSGALNACT1 2 GO:0050136 NADH dehydrogenase (quinone) activity 1/123 43/18367 0.251184474609249 0.427943919704646 NDUFS2 1 GO:0001784 phosphotyrosine residue binding 1/123 44/18367 0.256210904953227 0.429687038515307 SH3BP2 1 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/123 44/18367 0.256210904953227 0.429687038515307 PRKAA2 1 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/123 44/18367 0.256210904953227 0.429687038515307 GAPDH 1 GO:0019842 vitamin binding 2/123 148/18367 0.260938690034762 0.431321258664084 EGLN3/RBP1 2 GO:0003954 NADH dehydrogenase activity 1/123 45/18367 0.261203867824523 0.431321258664084 NDUFS2 1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity 1/123 45/18367 0.261203867824523 0.431321258664084 NDUFS2 1 GO:0140677 molecular function activator activity 2/123 150/18367 0.265902432227407 0.436839710087883 NUPR1/APOC1 2 GO:0015081 sodium ion transmembrane transporter activity 2/123 152/18367 0.270866420953742 0.440863980606693 SCN3B/SCNN1B 2 GO:0005044 scavenger receptor activity 1/123 47/18367 0.271090273789209 0.440863980606693 CD163L1 1 GO:0008017 microtubule binding 3/123 271/18367 0.272794914390469 0.441406846400658 MX1/MX2/GAPDH 3 GO:0005319 lipid transporter activity 2/123 154/18367 0.275829772242285 0.44408593331008 OSBPL1A/FABP4 2 GO:0016763 pentosyltransferase activity 1/123 49/18367 0.280845443363323 0.447684320608861 TYMP 1 GO:0098632 cell-cell adhesion mediator activity 1/123 49/18367 0.280845443363323 0.447684320608861 SIRPA 1 GO:0015485 cholesterol binding 1/123 50/18367 0.285674355387906 0.450917364876988 OSBPL1A 1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/123 50/18367 0.285674355387906 0.450917364876988 CCND2 1 GO:0051018 protein kinase A binding 1/123 51/18367 0.290471104543733 0.456252173966254 AKAP12 1 GO:0004879 nuclear receptor activity 1/123 52/18367 0.295235903306625 0.457047888772756 NR2F1 1 GO:0008146 sulfotransferase activity 1/123 52/18367 0.295235903306625 0.457047888772756 CHST15 1 GO:0098531 ligand-activated transcription factor activity 1/123 52/18367 0.295235903306625 0.457047888772756 NR2F1 1 GO:0017069 snRNA binding 1/123 53/18367 0.299968962760257 0.459952409565728 ISG20 1 GO:1901618 organic hydroxy compound transmembrane transporter activity 1/123 53/18367 0.299968962760257 0.459952409565728 MFSD10 1 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/123 54/18367 0.304670492605212 0.464947386819328 EGLN3 1 GO:0005080 protein kinase C binding 1/123 55/18367 0.309340701167957 0.469847668755105 PARD6G 1 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/123 56/18367 0.313979795409784 0.470574907620585 GAS6 1 GO:0045309 protein phosphorylated amino acid binding 1/123 56/18367 0.313979795409784 0.470574907620585 SH3BP2 1 GO:0001664 G protein-coupled receptor binding 3/123 295/18367 0.316609139181287 0.470574907620585 CCL21/CCL4/CCL14 3 GO:0030674 protein-macromolecule adaptor activity 3/123 296/18367 0.318442231406437 0.470574907620585 GAS6/STON2/SPSB1 3 GO:0004536 deoxyribonuclease activity 1/123 57/18367 0.318587980935676 0.470574907620585 ISG20 1 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/123 57/18367 0.318587980935676 0.470574907620585 NDUFS2 1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/123 58/18367 0.32316546200312 0.475156524041118 GSTM3 1 GO:0046873 metal ion transmembrane transporter activity 4/123 430/18367 0.325378652123269 0.476236027198602 GPM6A/SCN3B/SLC39A14/SCNN1B 4 GO:0098631 cell adhesion mediator activity 1/123 59/18367 0.327712441530873 0.476352438253961 SIRPA 1 GO:0005216 ion channel activity 4/123 432/18367 0.328416898423538 0.476352438253961 GPM6A/SCN3B/PIEZO2/SCNN1B 4 GO:0001786 phosphatidylserine binding 1/123 60/18367 0.332229121107654 0.477579361592252 GAS6 1 GO:0032934 sterol binding 1/123 60/18367 0.332229121107654 0.477579361592252 OSBPL1A 1 GO:0005507 copper ion binding 1/123 61/18367 0.336715701000796 0.479745379302019 LOX 1 GO:0015179 L-amino acid transmembrane transporter activity 1/123 61/18367 0.336715701000796 0.479745379302019 SLC7A1 1 GO:0003779 actin binding 4/123 440/18367 0.340586831443514 0.483123170593883 FLNC/SMTN/PDLIM4/S100A4 4 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 3/123 310/18367 0.344109021223205 0.485978529973123 PROX1/HIC1/NR2F1 3 GO:0001217 DNA-binding transcription repressor activity 3/123 313/18367 0.349603662494252 0.49080106833421 PROX1/HIC1/NR2F1 3 GO:0008509 anion transmembrane transporter activity 3/123 314/18367 0.351434313686222 0.49080106833421 SLC39A14/MFSD10/SLC7A1 3 GO:0008514 organic anion transmembrane transporter activity 2/123 185/18367 0.352096418587586 0.49080106833421 MFSD10/SLC7A1 2 GO:0043022 ribosome binding 1/123 66/18367 0.358704023149124 0.497856445922492 CPEB2 1 GO:0016782 transferase activity, transferring sulphur-containing groups 1/123 68/18367 0.367295518018492 0.507592947647872 CHST15 1 GO:0004857 enzyme inhibitor activity 1/123 70/18367 0.375772835259032 0.517089115185506 APOC1 1 GO:0000049 tRNA binding 1/123 72/18367 0.384137479973651 0.521908306124539 DTD1 1 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/123 72/18367 0.384137479973651 0.521908306124539 NDUFS2 1 GO:0030276 clathrin binding 1/123 72/18367 0.384137479973651 0.521908306124539 STON2 1 GO:0003730 mRNA 3'-UTR binding 2/123 201/18367 0.390466648826135 0.526068037330609 CPEB2/PABPC1 2 GO:0005516 calmodulin binding 2/123 201/18367 0.390466648826135 0.526068037330609 AKAP12/RGS16 2 GO:0003725 double-stranded RNA binding 1/123 74/18367 0.392390937586638 0.526457841262073 OAS1 1 GO:0022836 gated channel activity 3/123 340/18367 0.398745933614808 0.532764276448 SCN3B/PIEZO2/SCNN1B 3 GO:0015267 channel activity 4/123 480/18367 0.401463626803193 0.533988116069039 GPM6A/SCN3B/PIEZO2/SCNN1B 4 GO:0022803 passive transmembrane transporter activity 4/123 481/18367 0.402978609331604 0.533988116069039 GPM6A/SCN3B/PIEZO2/SCNN1B 4 GO:0001221 transcription coregulator binding 1/123 78/18367 0.408570136339541 0.539178622546444 EPAS1 1 GO:0004518 nuclease activity 2/123 210/18367 0.411613666551385 0.540001476108657 REXO2/ISG20 2 GO:0046332 SMAD binding 1/123 79/18367 0.412547711561272 0.540001476108657 SMAD1 1 GO:0001540 amyloid-beta binding 1/123 84/18367 0.432041063351678 0.55870370441462 TGFB2 1 GO:0008135 translation factor activity, RNA binding 1/123 84/18367 0.432041063351678 0.55870370441462 CPEB2 1 GO:0015171 amino acid transmembrane transporter activity 1/123 84/18367 0.432041063351678 0.55870370441462 SLC7A1 1 GO:0050660 flavin adenine dinucleotide binding 1/123 85/18367 0.435862041812967 0.560571274566863 MTHFR 1 GO:0000287 magnesium ion binding 2/123 221/18367 0.436967049429449 0.560571274566863 PDE2A/PGM5 2 GO:0005085 guanyl-nucleotide exchange factor activity 2/123 223/18367 0.441514438774294 0.562741995936441 RAB3IL1/RPGR 2 GO:0003727 single-stranded RNA binding 1/123 87/18367 0.443427672695866 0.562741995936441 PABPC1 1 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/123 88/18367 0.447172661550265 0.562741995936441 NDUFS2 1 GO:0051219 phosphoprotein binding 1/123 88/18367 0.447172661550265 0.562741995936441 SH3BP2 1 GO:0060090 molecular adaptor activity 3/123 369/18367 0.450383243025902 0.562741995936441 GAS6/STON2/SPSB1 3 GO:0008081 phosphoric diester hydrolase activity 1/123 89/18367 0.450892655129198 0.562741995936441 PDE2A 1 GO:0015297 antiporter activity 1/123 89/18367 0.450892655129198 0.562741995936441 SLC35E4 1 GO:0005539 glycosaminoglycan binding 2/123 230/18367 0.457271499202303 0.568499701710971 LYVE1/LAYN 2 GO:0015631 tubulin binding 3/123 375/18367 0.460856551308965 0.569858961446457 MX1/MX2/GAPDH 3 GO:0051213 dioxygenase activity 1/123 92/18367 0.461904313470575 0.569858961446457 EGLN3 1 GO:0015291 secondary active transmembrane transporter activity 2/123 240/18367 0.479335820192554 0.587479504435803 SLC35E4/SLC39A14 2 GO:0140098 catalytic activity, acting on RNA 3/123 386/18367 0.479835744306261 0.587479504435803 REXO2/ISG20/DTD1 3 GO:0005496 steroid binding 1/123 100/18367 0.49020945247891 0.597906983705338 OSBPL1A 1 GO:0005200 structural constituent of cytoskeleton 1/123 103/18367 0.500438776802609 0.608080325020529 SYNM 1 GO:0015294 solute:cation symporter activity 1/123 104/18367 0.503803101728873 0.609866912619162 SLC39A14 1 GO:0022804 active transmembrane transporter activity 3/123 406/18367 0.513529979827896 0.617280999332895 SLC35E4/SLC39A14/NDUFS2 3 GO:0051087 chaperone binding 1/123 107/18367 0.513761825531727 0.617280999332895 PDPN 1 GO:1901681 sulfur compound binding 2/123 265/18367 0.532046721470236 0.635757216277779 GSTM3/CHST15 2 GO:0099094 ligand-gated cation channel activity 1/123 113/18367 0.533088349052796 0.635757216277779 SCNN1B 1 GO:0005262 calcium channel activity 1/123 119/18367 0.551652698861852 0.65546925842626 GPM6A 1 GO:0005179 hormone activity 1/123 122/18367 0.560658423398325 0.663720633581841 METRNL 1 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/123 124/18367 0.566562323750861 0.665814117692618 FLT4 1 GO:0140101 catalytic activity, acting on a tRNA 1/123 124/18367 0.566562323750861 0.665814117692618 DTD1 1 GO:0009055 electron transfer activity 1/123 126/18367 0.572387523521565 0.670213754814341 NDUFS2 1 GO:0042826 histone deacetylase binding 1/123 127/18367 0.57527093641597 0.671149425818632 HIC1 1 GO:0016779 nucleotidyltransferase activity 1/123 132/18367 0.589401257429636 0.685152364232284 OAS1 1 GO:0031625 ubiquitin protein ligase binding 2/123 297/18367 0.594085139629959 0.686627752144281 ISG15/NDUFS2 2 GO:0015085 calcium ion transmembrane transporter activity 1/123 135/18367 0.597654586165925 0.686627752144281 GPM6A 1 GO:0043177 organic acid binding 1/123 135/18367 0.597654586165925 0.686627752144281 EGLN3 1 GO:0004713 protein tyrosine kinase activity 1/123 136/18367 0.600368961215376 0.686627752144281 FLT4 1 GO:0005096 GTPase activator activity 3/123 462/18367 0.601332379207103 0.686627752144281 RGS16/RAB3IL1/RPGR 3 GO:0005543 phospholipid binding 3/123 466/18367 0.607199063394605 0.688964317454153 APOC1/GAS6/OSBPL1A 3 GO:0099106 ion channel regulator activity 1/123 139/18367 0.608403581893797 0.688964317454153 SCN3B 1 GO:0070851 growth factor receptor binding 1/123 141/18367 0.613670771038752 0.688964317454153 IL7 1 GO:0015276 ligand-gated ion channel activity 1/123 143/18367 0.618867681863634 0.688964317454153 SCNN1B 1 GO:0019199 transmembrane receptor protein kinase activity 1/123 143/18367 0.618867681863634 0.688964317454153 FLT4 1 GO:0022834 ligand-gated channel activity 1/123 143/18367 0.618867681863634 0.688964317454153 SCNN1B 1 GO:0015293 symporter activity 1/123 144/18367 0.621440074045964 0.688964317454153 SLC39A14 1 GO:0016922 nuclear receptor binding 1/123 144/18367 0.621440074045964 0.688964317454153 PROX1 1 GO:0016247 channel regulator activity 1/123 145/18367 0.623995244484001 0.688964317454153 SCN3B 1 GO:0044389 ubiquitin-like protein ligase binding 2/123 316/18367 0.62794810303413 0.688964317454153 ISG15/NDUFS2 2 GO:0008528 G protein-coupled peptide receptor activity 1/123 147/18367 0.629054376805966 0.688964317454153 APLNR 1 GO:0052689 carboxylic ester hydrolase activity 1/123 147/18367 0.629054376805966 0.688964317454153 DTD1 1 GO:0043021 ribonucleoprotein complex binding 1/123 149/18367 0.634045984685152 0.692077312097014 CPEB2 1 GO:0042277 peptide binding 2/123 321/18367 0.63649085114817 0.69239883131659 GSTM3/TGFB2 2 GO:0005506 iron ion binding 1/123 151/18367 0.638970962083595 0.692756396602416 EGLN3 1 GO:0015103 inorganic anion transmembrane transporter activity 1/123 152/18367 0.641408740501673 0.69306582027362 SLC39A14 1 GO:0001653 peptide receptor activity 1/123 153/18367 0.64383019122461 0.69335559054958 APLNR 1 GO:0046943 carboxylic acid transmembrane transporter activity 1/123 163/18367 0.667170188271585 0.716096002078167 SLC7A1 1 GO:0005342 organic acid transmembrane transporter activity 1/123 164/18367 0.669419038350831 0.716122692189261 SLC7A1 1 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/123 170/18367 0.682599105879035 0.727682307399848 EGLN3 1 GO:0003823 antigen binding 1/123 171/18367 0.684744531497372 0.727682307399848 SIRPA 1 GO:0015399 primary active transmembrane transporter activity 1/123 181/18367 0.705423213052086 0.746845286889729 NDUFS2 1 GO:0003735 structural constituent of ribosome 1/123 182/18367 0.707415566774432 0.746845286889729 ISG15 1 GO:0008022 protein C-terminus binding 1/123 189/18367 0.720992724809608 0.758691690812725 PABPC1 1 GO:0008236 serine-type peptidase activity 1/123 191/18367 0.724755815115685 0.760167337026875 RELN 1 GO:0017171 serine hydrolase activity 1/123 195/18367 0.732131622004965 0.765410332096099 RELN 1 GO:0005244 voltage-gated ion channel activity 1/123 201/18367 0.742829289204732 0.771583971367496 SCN3B 1 GO:0022832 voltage-gated channel activity 1/123 201/18367 0.742829289204732 0.771583971367496 SCN3B 1 GO:0033218 amide binding 2/123 400/18367 0.751872256758267 0.778465809248109 GSTM3/TGFB2 2 GO:0051015 actin filament binding 1/123 217/18367 0.769329017543553 0.793986998875077 FLNC 1 GO:0140097 catalytic activity, acting on DNA 1/123 229/18367 0.787409360814844 0.810050524544345 ISG20 1 GO:0003713 transcription coactivator activity 1/123 262/18367 0.830199724697564 0.851351310040177 NUPR1 1 GO:0022853 active ion transmembrane transporter activity 1/123 267/18367 0.835890368663376 0.854465710189229 SLC39A14 1 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 1/123 299/18367 0.868086531299442 0.884569186957027 PROX1 1 GO:0046982 protein heterodimerization activity 1/123 328/18367 0.891809227379509 0.905875618978555 EPAS1 1 GO:0106310 protein serine kinase activity 1/123 360/18367 0.913099316735065 0.924584842731733 PRKAA2 1 GO:0042578 phosphoric ester hydrolase activity 1/123 366/18367 0.916601069321546 0.925221142073786 PDE2A 1 GO:0004674 protein serine/threonine kinase activity 1/123 386/18367 0.92729321475181 0.933088797344009 PRKAA2 1 GO:0140297 DNA-binding transcription factor binding 1/123 394/18367 0.931178821690075 0.934079690293471 PROX1 1 GO:0003712 transcription coregulator activity 1/123 489/18367 0.964219005166766 0.964219005166766 NUPR1 1