ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	Count
GO:0004601	peroxidase activity	8/139	51/18367	4.25214821229239e-09	9.16841551158843e-07	PTGS2/HBA2/HBG1/HBA1/GPX1/HBM/HBB/PRDX6	8
GO:0031720	haptoglobin binding	5/139	10/18367	5.64534538625082e-09	9.16841551158843e-07	HBA2/HBG1/HBA1/HBM/HBB	5
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	8/139	55/18367	7.9265840157825e-09	9.16841551158843e-07	PTGS2/HBA2/HBG1/HBA1/GPX1/HBM/HBB/PRDX6	8
GO:0005344	oxygen carrier activity	5/139	14/18367	4.37689600739522e-08	3.79695728641535e-06	HBA2/HBG1/HBA1/HBM/HBB	5
GO:0016209	antioxidant activity	8/139	86/18367	2.83713971739273e-07	1.96897496387055e-05	PTGS2/HBA2/HBG1/HBA1/GPX1/HBM/HBB/PRDX6	8
GO:0019825	oxygen binding	5/139	39/18367	1.0811716729392e-05	0.000625277617516502	HBA2/HBG1/HBA1/HBM/HBB	5
GO:0140297	DNA-binding transcription factor binding	12/139	394/18367	4.62224647465743e-05	0.00229131360958018	FOS/NFKBIA/CEBPB/JUND/DDX5/HMGB1/JUN/HIF1A/ETS2/BCL3/PTMA/TAF10	12
GO:0044389	ubiquitin-like protein ligase binding	10/139	316/18367	0.00014830645159488	0.00643279233792793	TRIB1/NFKBIA/CEBPB/GABARAPL2/JUN/ACTG1/CXCR4/HIF1A/UBB/PRDX6	10
GO:0140104	molecular carrier activity	5/139	73/18367	0.000229550331586692	0.00885044056228691	HBA2/HBG1/HBA1/HBM/HBB	5
GO:0031625	ubiquitin protein ligase binding	9/139	297/18367	0.000438185024098734	0.0145103115377796	TRIB1/NFKBIA/GABARAPL2/JUN/ACTG1/CXCR4/HIF1A/UBB/PRDX6	9
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	9/139	299/18367	0.000459981057393589	0.0145103115377796	FOS/NFKBIA/CEBPB/JUND/DDX5/JUN/HIF1A/ETS2/TAF10	9
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	11/139	450/18367	0.000634496540379729	0.0163184485296342	FOS/JUNB/EGR1/CEBPB/JUND/FOSB/CSRNP1/JUN/HIF1A/EGR3/REL	11
GO:0020037	heme binding	6/139	139/18367	0.000664341218524053	0.0163184485296342	PTGS2/HBA2/HBG1/HBA1/HBM/HBB	6
GO:0070412	R-SMAD binding	3/139	23/18367	0.000672300483609311	0.0163184485296342	FOS/DDX5/JUN	3
GO:0001216	DNA-binding transcription activator activity	11/139	456/18367	0.000707548042246189	0.0163184485296342	FOS/JUNB/EGR1/CEBPB/JUND/FOSB/CSRNP1/JUN/HIF1A/EGR3/REL	11
GO:0005178	integrin binding	6/139	144/18367	0.000799462896264502	0.0163184485296342	FN1/HMGB1/TLN1/FBN1/MYH9/IL1B	6
GO:0016922	nuclear receptor binding	6/139	144/18367	0.000799462896264502	0.0163184485296342	CEBPB/JUND/DDX5/HIF1A/ETS2/TAF10	6
GO:0046906	tetrapyrrole binding	6/139	149/18367	0.000954895399671408	0.0184082613158877	PTGS2/HBA2/HBG1/HBA1/HBM/HBB	6
GO:0071889	14-3-3 protein binding	3/139	32/18367	0.00179156111732142	0.0327195635637123	ZFP36/DDIT4/IRS2	3
GO:0019956	chemokine binding	3/139	33/18367	0.00195987798040757	0.0340038829600713	ZFP36/HMGB1/CXCR4	3
GO:0035198	miRNA binding	3/139	34/18367	0.00213772488402148	0.0353233587978787	YBX1/DDX21/HNRNPA2B1	3
GO:0003697	single-stranded DNA binding	5/139	123/18367	0.00244378510597334	0.0355537602945394	HMGB1/YBX1/ANXA1/HNRNPA2B1/HMGB2	5
GO:0008330	protein tyrosine/threonine phosphatase activity	2/139	10/18367	0.00245904970336872	0.0355537602945394	DUSP1/DUSP2	2
GO:0050786	RAGE receptor binding	2/139	10/18367	0.00245904970336872	0.0355537602945394	HMGB1/HMGB2	2
GO:0042056	chemoattractant activity	3/139	37/18367	0.00273025330758452	0.0378959159092731	HMGB1/HMGB2/MIF	3
GO:0051400	BH domain binding	2/139	11/18367	0.0029906282742844	0.0391099291056039	BCL2A1/MCL1	2
GO:0046332	SMAD binding	4/139	79/18367	0.00304313569409598	0.0391099291056039	FOS/DDX5/JUN/SKIL	4
GO:0043177	organic acid binding	5/139	135/18367	0.00364920743804576	0.0452241064643528	HBA2/HBG1/HBA1/HBM/HBB	5
GO:0045296	cadherin binding	8/139	332/18367	0.00380976820700885	0.0455858471666232	LDHA/TLN1/MYH9/ANXA1/BZW1/CHMP5/PRDX6/ZC3H15	8
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/139	13/18367	0.00419940823538332	0.0485731552559337	DUSP1/DUSP2	2
GO:0019888	protein phosphatase regulator activity	4/139	89/18367	0.00466668779812386	0.0512624334502781	PPP1R15A/PPP1R10/PHACTR1/PPP1R15B	4
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/139	14/18367	0.00487510174022818	0.0512624334502781	IDI1/MIF	2
GO:0035259	glucocorticoid receptor binding	2/139	14/18367	0.00487510174022818	0.0512624334502781	CEBPB/ETS2	2
GO:0061980	regulatory RNA binding	3/139	46/18367	0.00507649939082922	0.0518101555475806	YBX1/DDX21/HNRNPA2B1	3
GO:0005506	iron ion binding	5/139	151/18367	0.00585282581316928	0.0580265873477069	HBA2/HBA1/SNCA/FTH1/JMJD6	5
GO:0000400	four-way junction DNA binding	2/139	17/18367	0.00717852657011339	0.0691930199952596	HMGB1/HMGB2	2
GO:0005200	structural constituent of cytoskeleton	4/139	103/18367	0.00779345918152436	0.06971259778809	TLN1/ACTG1/TUBA4A/KRT19	4
GO:0008301	DNA binding, bending	2/139	18/18367	0.00803603432715735	0.06971259778809	HMGB1/HMGB2	2
GO:0033549	MAP kinase phosphatase activity	2/139	18/18367	0.00803603432715735	0.06971259778809	DUSP1/DUSP2	2
GO:0045236	CXCR chemokine receptor binding	2/139	18/18367	0.00803603432715735	0.06971259778809	CXCL8/CXCL1	2
GO:0019208	phosphatase regulator activity	4/139	107/18367	0.00888922226173048	0.0745422577467858	PPP1R15A/PPP1R10/PHACTR1/PPP1R15B	4
GO:0005125	cytokine activity	6/139	235/18367	0.00902240583678675	0.0745422577467858	CXCL8/OSM/HMGB1/IL1B/CXCL1/MIF	6
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/139	20/18367	0.00988133735434429	0.0797400944641271	FOS/CEBPB	2
GO:1990841	promoter-specific chromatin binding	3/139	62/18367	0.0115872930012658	0.0913816061690735	EGR1/DDX5/TAF10	3
GO:0004602	glutathione peroxidase activity	2/139	22/18367	0.0118957288743038	0.0917292870974096	GPX1/PRDX6	2
GO:0019957	C-C chemokine binding	2/139	24/18367	0.0140737652293246	0.106165142055992	ZFP36/CXCR4	2
GO:0035035	histone acetyltransferase binding	2/139	25/18367	0.015222482960177	0.112387267812371	EGR1/CEBPB	2
GO:0004860	protein kinase inhibitor activity	3/139	70/18367	0.0160558306073143	0.116070275432043	TRIB1/SNCA/SOCS3	3
GO:0008198	ferrous iron binding	2/139	26/18367	0.0164101264315684	0.116210487178658	SNCA/FTH1	2
GO:0005126	cytokine receptor binding	6/139	271/18367	0.0172056835999176	0.119407444183428	CXCL8/OSM/IL1B/LRG1/CXCL1/MIF	6
GO:0022884	macromolecule transmembrane transporter activity	2/139	27/18367	0.0176360495668029	0.119994298032953	MCL1/HNRNPA3	2
GO:0019210	kinase inhibitor activity	3/139	74/18367	0.0186045324363578	0.123629554466075	TRIB1/SNCA/SOCS3	3
GO:0003779	actin binding	8/139	440/18367	0.0188829002498616	0.123629554466075	LSP1/TPM3/SNCA/TLN1/MYH9/CXCR4/PHACTR1/KLHL2	8
GO:0019887	protein kinase regulator activity	5/139	204/18367	0.0195658535069679	0.125728725313294	TRIB1/CCNL1/SNCA/HMGB1/SOCS3	5
GO:0019955	cytokine binding	4/139	139/18367	0.0213454763756263	0.134670550951679	ZFP36/HMGB1/CXCR4/IL1R2	4
GO:0008157	protein phosphatase 1 binding	2/139	31/18367	0.0229098755654362	0.141959407521542	PPP1R15A/PHACTR1	2
GO:0008135	translation factor activity, RNA binding	3/139	84/18367	0.0259031613477305	0.157691175222149	EIF1/ETF1/GSPT1	3
GO:0003727	single-stranded RNA binding	3/139	87/18367	0.0283511499219762	0.169618086602168	HMGB1/ANXA1/JMJD6	3
GO:0051219	phosphoprotein binding	3/139	88/18367	0.0291935610630296	0.171697723540191	SAMSN1/SNCA/SOCS3	3
GO:0000217	DNA secondary structure binding	2/139	36/18367	0.0302889577531176	0.17517113900553	HMGB1/HMGB2	2
GO:0048018	receptor ligand activity	8/139	487/18367	0.0319854840982434	0.18051288020841	CXCL8/OSM/HMGB1/FBN1/IL1B/CXCL1/HMGB2/MIF	8
GO:0019207	kinase regulator activity	5/139	233/18367	0.0322530218239811	0.18051288020841	TRIB1/CCNL1/SNCA/HMGB1/SOCS3	5
GO:0016410	N-acyltransferase activity	3/139	94/18367	0.0345239394260788	0.188216774176535	SAT1/ALAS2/TAF10	3
GO:0030546	signaling receptor activator activity	8/139	495/18367	0.034714332989332	0.188216774176535	CXCL8/OSM/HMGB1/FBN1/IL1B/CXCL1/HMGB2/MIF	8
GO:0008201	heparin binding	4/139	166/18367	0.0374940452355479	0.20016051841131	FN1/PRG2/FBN1/AOC1	4
GO:0048487	beta-tubulin binding	2/139	41/18367	0.038473758715436	0.202278701125095	GABARAPL2/SNCA	2
GO:0001046	core promoter sequence-specific DNA binding	2/139	42/18367	0.0402012250513003	0.208206344668674	FOS/CEBPB	2
GO:0004725	protein tyrosine phosphatase activity	3/139	102/18367	0.042358573243594	0.216153307581281	DUSP1/PTPRE/DUSP2	3
GO:0001784	phosphotyrosine residue binding	2/139	44/18367	0.0437423389917982	0.219979588842811	SAMSN1/SOCS3	2
GO:0004864	protein phosphatase inhibitor activity	2/139	46/18367	0.0473948627759655	0.234943105475143	PPP1R10/PHACTR1	2
GO:0090079	translation regulator activity, nucleic acid binding	3/139	108/18367	0.0487691987156968	0.235971665523974	EIF1/ETF1/GSPT1	3
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	2/139	47/18367	0.0492616146388437	0.235971665523974	DUSP1/DUSP2	2
GO:0003735	structural constituent of ribosome	4/139	182/18367	0.0496424541304037	0.235971665523974	RPL36A/RPS10/RPL17/RPL7	4
GO:0008009	chemokine activity	2/139	49/18367	0.053073574176389	0.24555373652276	CXCL8/CXCL1	2
GO:0019212	phosphatase inhibitor activity	2/139	49/18367	0.053073574176389	0.24555373652276	PPP1R10/PHACTR1	2
GO:0003714	transcription corepressor activity	4/139	187/18367	0.05383414815089	0.24579538695209	BTG2/SRSF2/BCL3/SAP18	4
GO:0016860	intramolecular oxidoreductase activity	2/139	51/18367	0.0569868457472153	0.256810850315373	IDI1/MIF	2
GO:0005080	protein kinase C binding	2/139	55/18367	0.0651019267168822	0.289620109881514	PLEK/SRSF2	2
GO:0045309	protein phosphorylated amino acid binding	2/139	56/18367	0.0671880772525391	0.295117250716849	SAMSN1/SOCS3	2
GO:0042826	histone deacetylase binding	3/139	127/18367	0.0719525148061599	0.296015173469719	CEBPB/HIF1A/BCL3	3
GO:0005031	tumor necrosis factor-activated receptor activity	1/139	10/18367	0.0731705556910437	0.296015173469719	FAS	1
GO:0005522	profilin binding	1/139	10/18367	0.0731705556910437	0.296015173469719	ACTG1	1
GO:0098505	G-rich strand telomeric DNA binding	1/139	10/18367	0.0731705556910437	0.296015173469719	HNRNPA2B1	1
GO:0036002	pre-mRNA binding	2/139	59/18367	0.0735769724378316	0.296015173469719	DDX5/SRSF2	2
GO:0031072	heat shock protein binding	3/139	129/18367	0.0746356121780859	0.296015173469719	ZFP36/SNCA/HIF1A	3
GO:0001786	phosphatidylserine binding	2/139	60/18367	0.0757486119622057	0.296015173469719	HMGB1/TLN1	2
GO:0005507	copper ion binding	2/139	61/18367	0.0779405320756313	0.296015173469719	SNCA/AOC1	2
GO:0003712	transcription coregulator activity	7/139	489/18367	0.0783659265458807	0.296015173469719	BTG2/HMGB1/SRSF2/BCL3/SAP18/HMGB2/AKIRIN2	7
GO:0005536	glucose binding	1/139	11/18367	0.0801885484327194	0.296015173469719	SLC2A3	1
GO:0008199	ferric iron binding	1/139	11/18367	0.0801885484327194	0.296015173469719	FTH1	1
GO:0031434	mitogen-activated protein kinase kinase binding	1/139	11/18367	0.0801885484327194	0.296015173469719	TRIB1	1
GO:0070513	death domain binding	1/139	11/18367	0.0801885484327194	0.296015173469719	MCL1	1
GO:0097493	structural molecule activity conferring elasticity	1/139	11/18367	0.0801885484327194	0.296015173469719	FBN1	1
GO:0099186	structural constituent of postsynapse	1/139	11/18367	0.0801885484327194	0.296015173469719	ACTG1	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	5/139	310/18367	0.0867571555133429	0.302232644442346	CEBPB/NFIL3/JUN/ETS2/SKIL	5
GO:0017166	vinculin binding	1/139	12/18367	0.0871537800609531	0.302232644442346	TLN1	1
GO:0043047	single-stranded telomeric DNA binding	1/139	12/18367	0.0871537800609531	0.302232644442346	HNRNPA2B1	1
GO:0089720	caspase binding	1/139	12/18367	0.0871537800609531	0.302232644442346	RIOK3	1
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	4/139	222/18367	0.0883031568879175	0.302232644442346	SAT1/ALAS2/TAF10/PRDX6	4
GO:0002039	p53 binding	2/139	66/18367	0.0891896101464704	0.302232644442346	HIF1A/PLK3	2
GO:0001217	DNA-binding transcription repressor activity	5/139	313/18367	0.0895003524410307	0.302232644442346	CEBPB/NFIL3/JUN/ETS2/SKIL	5
GO:0045182	translation regulator activity	3/139	140/18367	0.0901631808940076	0.302232644442346	EIF1/ETF1/GSPT1	3
GO:0003684	damaged DNA binding	2/139	68/18367	0.0938166887051354	0.302232644442346	HMGB1/HMGB2	2
GO:0008080	N-acetyltransferase activity	2/139	68/18367	0.0938166887051354	0.302232644442346	SAT1/TAF10	2
GO:0004859	phospholipase inhibitor activity	1/139	13/18367	0.0940666443797503	0.302232644442346	ANXA1	1
GO:0005035	death receptor activity	1/139	13/18367	0.0940666443797503	0.302232644442346	FAS	1
GO:0031386	protein tag	1/139	13/18367	0.0940666443797503	0.302232644442346	UBB	1
GO:0072542	protein phosphatase activator activity	1/139	13/18367	0.0940666443797503	0.302232644442346	PPP1R15A	1
GO:0005539	glycosaminoglycan binding	4/139	230/18367	0.0973879401074821	0.308767121280703	FN1/PRG2/FBN1/AOC1	4
GO:0071837	HMG box domain binding	1/139	14/18367	0.100927532275098	0.308767121280703	JUN	1
GO:0140666	annealing activity	1/139	14/18367	0.100927532275098	0.308767121280703	ANXA1	1
GO:0042379	chemokine receptor binding	2/139	72/18367	0.103271969687673	0.308767121280703	CXCL8/CXCL1	2
GO:0043021	ribonucleoprotein complex binding	3/139	149/18367	0.10378426336909	0.308767121280703	EIF1/DDX5/ETF1	3
GO:0019903	protein phosphatase binding	3/139	150/18367	0.105345721110753	0.308767121280703	PPP1R15A/PHACTR1/IRS2	3
GO:0070063	RNA polymerase binding	2/139	73/18367	0.105675474295304	0.308767121280703	ZFP36/TAF10	2
GO:0106306	protein serine phosphatase activity	2/139	73/18367	0.105675474295304	0.308767121280703	DUSP1/DUSP2	2
GO:0106307	protein threonine phosphatase activity	2/139	73/18367	0.105675474295304	0.308767121280703	DUSP1/DUSP2	2
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/139	15/18367	0.107736831736427	0.308767121280703	PDE4B	1
GO:0098847	sequence-specific single stranded DNA binding	1/139	15/18367	0.107736831736427	0.308767121280703	HNRNPA2B1	1
GO:1990825	sequence-specific mRNA binding	1/139	15/18367	0.107736831736427	0.308767121280703	ETF1	1
GO:0003725	double-stranded RNA binding	2/139	74/18367	0.108094111569164	0.308767121280703	HMGB1/DDX21	2
GO:0001618	virus receptor activity	2/139	76/18367	0.112975338870571	0.308767121280703	CXCR4/CD55	2
GO:0005521	lamin binding	1/139	16/18367	0.114494927877917	0.308767121280703	BNIP3L	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/139	16/18367	0.114494927877917	0.308767121280703	AOC1	1
GO:0035497	cAMP response element binding	1/139	16/18367	0.114494927877917	0.308767121280703	JUN	1
GO:0046935	1-phosphatidylinositol-3-kinase regulator activity	1/139	16/18367	0.114494927877917	0.308767121280703	SOCS3	1
GO:0004386	helicase activity	3/139	156/18367	0.11490642739559	0.308767121280703	DDX5/DDX21/ANXA1	3
GO:0003724	RNA helicase activity	2/139	77/18367	0.115437217595756	0.308767121280703	DDX5/DDX21	2
GO:0140272	exogenous protein binding	2/139	77/18367	0.115437217595756	0.308767121280703	CXCR4/CD55	2
GO:0008186	ATP-dependent activity, acting on RNA	2/139	79/18367	0.120401760406803	0.308767121280703	DDX5/DDX21	2
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/139	17/18367	0.121202202959655	0.308767121280703	PTPRE	1
GO:0005149	interleukin-1 receptor binding	1/139	17/18367	0.121202202959655	0.308767121280703	IL1B	1
GO:0016722	oxidoreductase activity, acting on metal ions	1/139	17/18367	0.121202202959655	0.308767121280703	FTH1	1
GO:0017081	chloride channel regulator activity	1/139	17/18367	0.121202202959655	0.308767121280703	SGK1	1
GO:0019198	transmembrane receptor protein phosphatase activity	1/139	17/18367	0.121202202959655	0.308767121280703	PTPRE	1
GO:0043024	ribosomal small subunit binding	1/139	17/18367	0.121202202959655	0.308767121280703	EIF1	1
GO:0016746	acyltransferase activity	4/139	250/18367	0.121905174684312	0.308767121280703	SAT1/ALAS2/TAF10/PRDX6	4
GO:0048038	quinone binding	1/139	18/18367	0.127859036408625	0.312444265026711	AOC1	1
GO:0050811	GABA receptor binding	1/139	18/18367	0.127859036408625	0.312444265026711	GABARAPL2	1
GO:0055102	lipase inhibitor activity	1/139	18/18367	0.127859036408625	0.312444265026711	ANXA1	1
GO:0098641	cadherin binding involved in cell-cell adhesion	1/139	18/18367	0.127859036408625	0.312444265026711	ANXA1	1
GO:0098918	structural constituent of synapse	1/139	18/18367	0.127859036408625	0.312444265026711	ACTG1	1
GO:0106310	protein serine kinase activity	5/139	360/18367	0.138097270985084	0.332677902776487	STK17B/RIOK3/SGK1/MAP3K8/PLK3	5
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/139	20/18367	0.141022882075623	0.332677902776487	AOC1	1
GO:0019211	phosphatase activator activity	1/139	20/18367	0.141022882075623	0.332677902776487	PPP1R15A	1
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/139	20/18367	0.141022882075623	0.332677902776487	SOCS3	1
GO:1901681	sulfur compound binding	4/139	265/18367	0.1418591075773	0.332677902776487	FN1/PRG2/FBN1/AOC1	4
GO:0005201	extracellular matrix structural constituent	3/139	172/18367	0.141891439800922	0.332677902776487	FN1/PRG2/FBN1	3
GO:0048306	calcium-dependent protein binding	2/139	88/18367	0.143349065156362	0.333839769189648	DDX5/ANXA1	2
GO:0004721	phosphoprotein phosphatase activity	3/139	174/18367	0.145404103474253	0.336065013925268	DUSP1/PTPRE/DUSP2	3
GO:0016407	acetyltransferase activity	2/139	91/18367	0.151192117745	0.336065013925268	SAT1/TAF10	2
GO:0051213	dioxygenase activity	2/139	92/18367	0.153825392416181	0.336065013925268	PTGS2/JMJD6	2
GO:0005355	glucose transmembrane transporter activity	1/139	22/18367	0.153989444421088	0.336065013925268	SLC2A3	1
GO:0008320	protein transmembrane transporter activity	1/139	22/18367	0.153989444421088	0.336065013925268	MCL1	1
GO:0015149	hexose transmembrane transporter activity	1/139	22/18367	0.153989444421088	0.336065013925268	SLC2A3	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/139	22/18367	0.153989444421088	0.336065013925268	PRG2	1
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/139	22/18367	0.153989444421088	0.336065013925268	SNCA	1
GO:0055106	ubiquitin-protein transferase regulator activity	1/139	22/18367	0.153989444421088	0.336065013925268	TRIB1	1
GO:0070182	DNA polymerase binding	1/139	22/18367	0.153989444421088	0.336065013925268	HMGB1	1
GO:0072341	modified amino acid binding	2/139	93/18367	0.156467646688186	0.3371565805542	HMGB1/TLN1	2
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/139	23/18367	0.160399663403126	0.3371565805542	PDE4B	1
GO:0005158	insulin receptor binding	1/139	23/18367	0.160399663403126	0.3371565805542	IRS2	1
GO:0016493	C-C chemokine receptor activity	1/139	23/18367	0.160399663403126	0.3371565805542	CXCR4	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/139	23/18367	0.160399663403126	0.3371565805542	PTGS2	1
GO:0030552	cAMP binding	1/139	23/18367	0.160399663403126	0.3371565805542	PDE4B	1
GO:0015145	monosaccharide transmembrane transporter activity	1/139	24/18367	0.1667616589759	0.3371565805542	SLC2A3	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/139	24/18367	0.1667616589759	0.3371565805542	PTGS2	1
GO:0043274	phospholipase binding	1/139	24/18367	0.1667616589759	0.3371565805542	SNCA	1
GO:0043495	protein-membrane adaptor activity	1/139	24/18367	0.1667616589759	0.3371565805542	MYH9	1
GO:0051537	2 iron, 2 sulfur cluster binding	1/139	24/18367	0.1667616589759	0.3371565805542	GLRX5	1
GO:0070840	dynein complex binding	1/139	24/18367	0.1667616589759	0.3371565805542	SNCA	1
GO:0004896	cytokine receptor activity	2/139	97/18367	0.167120841081621	0.3371565805542	CXCR4/IL1R2	2
GO:0004674	protein serine/threonine kinase activity	5/139	386/18367	0.169102683478124	0.337400559463658	STK17B/RIOK3/SGK1/MAP3K8/PLK3	5
GO:0004722	protein serine/threonine phosphatase activity	2/139	98/18367	0.169803811487762	0.337400559463658	DUSP1/DUSP2	2
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/139	25/18367	0.173075791309888	0.337400559463658	PDE4B	1
GO:0005160	transforming growth factor beta receptor binding	1/139	25/18367	0.173075791309888	0.337400559463658	LRG1	1
GO:0035925	mRNA 3'-UTR AU-rich region binding	1/139	25/18367	0.173075791309888	0.337400559463658	ZFP36	1
GO:0051019	mitogen-activated protein kinase binding	1/139	25/18367	0.173075791309888	0.337400559463658	DUSP1	1
GO:0001637	G protein-coupled chemoattractant receptor activity	1/139	26/18367	0.179342417905021	0.345732327850235	CXCR4	1
GO:0004950	chemokine receptor activity	1/139	26/18367	0.179342417905021	0.345732327850235	CXCR4	1
GO:0004709	MAP kinase kinase kinase activity	1/139	27/18367	0.185561893610337	0.350348516992202	MAP3K8	1
GO:0008139	nuclear localization sequence binding	1/139	27/18367	0.185561893610337	0.350348516992202	NFKBIA	1
GO:0051119	sugar transmembrane transporter activity	1/139	27/18367	0.185561893610337	0.350348516992202	SLC2A3	1
GO:0019902	phosphatase binding	3/139	196/18367	0.185775582497306	0.350348516992202	PPP1R15A/PHACTR1/IRS2	3
GO:0050681	androgen receptor binding	1/139	28/18367	0.191734570643498	0.35946438281531	DDX5	1
GO:0003730	mRNA 3'-UTR binding	3/139	201/18367	0.195336217524778	0.35946438281531	ZFP36/DDX5/HNRNPA2B1	3
GO:0005516	calmodulin binding	3/139	201/18367	0.195336217524778	0.35946438281531	DDX5/MYH9/FAS	3
GO:0032452	histone demethylase activity	1/139	29/18367	0.197860798610156	0.35946438281531	JMJD6	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	1/139	29/18367	0.197860798610156	0.35946438281531	PLEK	1
GO:0051059	NF-kappaB binding	1/139	29/18367	0.197860798610156	0.35946438281531	NFKBIA	1
GO:0140457	protein demethylase activity	1/139	29/18367	0.197860798610156	0.35946438281531	JMJD6	1
GO:0000149	SNARE binding	2/139	110/18367	0.202498907417859	0.365974587885401	GABARAPL2/SNCA	2
GO:0000146	microfilament motor activity	1/139	31/18367	0.20997529282178	0.371741972495703	MYH9	1
GO:0043015	gamma-tubulin binding	1/139	31/18367	0.20997529282178	0.371741972495703	PDE4B	1
GO:0090482	vitamin transmembrane transporter activity	1/139	31/18367	0.20997529282178	0.371741972495703	SLC2A3	1
GO:0140318	protein transporter activity	1/139	31/18367	0.20997529282178	0.371741972495703	MCL1	1
GO:0001223	transcription coactivator binding	1/139	32/18367	0.215964245390376	0.378482793689195	HIF1A	1
GO:0030515	snoRNA binding	1/139	32/18367	0.215964245390376	0.378482793689195	DDX21	1
GO:0001530	lipopolysaccharide binding	1/139	33/18367	0.22190812157749	0.385010590936945	HMGB1	1
GO:0004623	phospholipase A2 activity	1/139	33/18367	0.22190812157749	0.385010590936945	PRDX6	1
GO:0051015	actin filament binding	3/139	217/18367	0.226682148584828	0.391332270298958	TPM3/TLN1/MYH9	3
GO:0043548	phosphatidylinositol 3-kinase binding	1/139	34/18367	0.227807258214379	0.391332270298958	IRS2	1
GO:0046982	protein heterodimerization activity	4/139	328/18367	0.237199636826046	0.401434824867129	CEBPB/BCL2A1/MCL1/HIF1A	4
GO:0042162	telomeric DNA binding	1/139	36/18367	0.239472647687307	0.401434824867129	HNRNPA2B1	1
GO:0043394	proteoglycan binding	1/139	36/18367	0.239472647687307	0.401434824867129	FN1	1
GO:0061631	ubiquitin conjugating enzyme activity	1/139	36/18367	0.239472647687307	0.401434824867129	UBE2S	1
GO:0097718	disordered domain specific binding	1/139	36/18367	0.239472647687307	0.401434824867129	FN1	1
GO:0015035	protein-disulfide reductase activity	1/139	37/18367	0.245239561765724	0.405229180631935	GLRX5	1
GO:0030551	cyclic nucleotide binding	1/139	37/18367	0.245239561765724	0.405229180631935	PDE4B	1
GO:0043531	ADP binding	1/139	37/18367	0.245239561765724	0.405229180631935	MYH9	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/139	38/18367	0.250963058815073	0.412721238904409	TAF10	1
GO:0004402	histone acetyltransferase activity	1/139	39/18367	0.256643463355676	0.415577812020236	TAF10	1
GO:0032451	demethylase activity	1/139	39/18367	0.256643463355676	0.415577812020236	JMJD6	1
GO:0061650	ubiquitin-like protein conjugating enzyme activity	1/139	39/18367	0.256643463355676	0.415577812020236	UBE2S	1
GO:0015144	carbohydrate transmembrane transporter activity	1/139	40/18367	0.262281097499803	0.415577812020236	SLC2A3	1
GO:0017080	sodium channel regulator activity	1/139	40/18367	0.262281097499803	0.415577812020236	SGK1	1
GO:0031492	nucleosomal DNA binding	1/139	40/18367	0.262281097499803	0.415577812020236	HMGN1	1
GO:0043014	alpha-tubulin binding	1/139	40/18367	0.262281097499803	0.415577812020236	SNCA	1
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	1/139	40/18367	0.262281097499803	0.415577812020236	SNCA	1
GO:0030331	estrogen receptor binding	1/139	41/18367	0.267876280969412	0.420602124418036	TAF10	1
GO:0061733	peptide-lysine-N-acetyltransferase activity	1/139	41/18367	0.267876280969412	0.420602124418036	TAF10	1
GO:0002020	protease binding	2/139	135/18367	0.272258413943722	0.421688790650993	FN1/RIOK3	2
GO:0008307	structural constituent of muscle	1/139	42/18367	0.273429331113756	0.421688790650993	KRT19	1
GO:0015036	disulfide oxidoreductase activity	1/139	42/18367	0.273429331113756	0.421688790650993	GLRX5	1
GO:0019894	kinesin binding	1/139	42/18367	0.273429331113756	0.421688790650993	SNCA	1
GO:0005246	calcium channel regulator activity	1/139	43/18367	0.278940562926864	0.424527961998341	SGK1	1
GO:0016504	peptidase activator activity	1/139	43/18367	0.278940562926864	0.424527961998341	FN1	1
GO:0030544	Hsp70 protein binding	1/139	43/18367	0.278940562926864	0.424527961998341	SNCA	1
GO:0004712	protein serine/threonine/tyrosine kinase activity	1/139	44/18367	0.284410289064888	0.429088566545722	SGK1	1
GO:0051879	Hsp90 protein binding	1/139	44/18367	0.284410289064888	0.429088566545722	HIF1A	1
GO:0019838	growth factor binding	2/139	141/18367	0.289074439047926	0.431648371212781	DUSP1/IL1R2	2
GO:0048156	tau protein binding	1/139	45/18367	0.289838819863337	0.431648371212781	SNCA	1
GO:0140223	general transcription initiation factor activity	1/139	45/18367	0.289838819863337	0.431648371212781	TAF10	1
GO:0140375	immune receptor activity	2/139	144/18367	0.297468275264238	0.441117485114062	CXCR4/IL1R2	2
GO:0042578	phosphoric ester hydrolase activity	4/139	366/18367	0.300625167331627	0.443901842825849	DUSP1/PTPRE/DUSP2/PDE4B	4
GO:0015026	coreceptor activity	1/139	48/18367	0.305880309124776	0.447850072853575	CXCR4	1
GO:0070888	E-box binding	1/139	48/18367	0.305880309124776	0.447850072853575	HIF1A	1
GO:0034212	peptide N-acetyltransferase activity	1/139	49/18367	0.311147116102867	0.45174916019956	TAF10	1
GO:0098632	cell-cell adhesion mediator activity	1/139	49/18367	0.311147116102867	0.45174916019956	ANXA1	1
GO:0140677	molecular function activator activity	2/139	150/18367	0.314208791442825	0.451777214343805	CXCL1/JMJD6	2
GO:0005048	signal sequence binding	1/139	50/18367	0.316374245203298	0.451777214343805	NFKBIA	1
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/139	50/18367	0.316374245203298	0.451777214343805	HNRNPA3	1
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/139	50/18367	0.316374245203298	0.451777214343805	CCNL1	1
GO:0003713	transcription coactivator activity	3/139	262/18367	0.318594678148393	0.453083415235625	HMGB1/BCL3/HMGB2	3
GO:0003743	translation initiation factor activity	1/139	51/18367	0.32156199319242	0.455436782194979	EIF1	1
GO:0017069	snRNA binding	1/139	53/18367	0.331820521900627	0.465742964797735	DDX21	1
GO:0016853	isomerase activity	2/139	158/18367	0.336391290983423	0.465742964797735	IDI1/MIF	2
GO:0005544	calcium-dependent phospholipid binding	1/139	54/18367	0.336891885199514	0.465742964797735	ANXA1	1
GO:0008374	O-acyltransferase activity	1/139	54/18367	0.336891885199514	0.465742964797735	PRDX6	1
GO:0015459	potassium channel regulator activity	1/139	54/18367	0.336891885199514	0.465742964797735	SGK1	1
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	1/139	54/18367	0.336891885199514	0.465742964797735	JMJD6	1
GO:0030170	pyridoxal phosphate binding	1/139	55/18367	0.341925032578823	0.469066335579231	ALAS2	1
GO:0016791	phosphatase activity	3/139	275/18367	0.345512869608961	0.469066335579231	DUSP1/PTPRE/DUSP2	3
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/139	56/18367	0.346920249948391	0.469066335579231	SNCA	1
GO:0051287	NAD binding	1/139	56/18367	0.346920249948391	0.469066335579231	LDHA	1
GO:0070279	vitamin B6 binding	1/139	56/18367	0.346920249948391	0.469066335579231	ALAS2	1
GO:0008083	growth factor activity	2/139	162/18367	0.347406479088941	0.469066335579231	OSM/CXCL1	2
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	1/139	57/18367	0.351877821094542	0.473262030696923	GLRX5	1
GO:0098631	cell adhesion mediator activity	1/139	59/18367	0.361681149338114	0.48456895297423	ANXA1	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	2/139	170/18367	0.369251143253714	0.492808256573227	PTGS2/JMJD6	2
GO:0043022	ribosome binding	1/139	66/18367	0.394847674912768	0.524950740209696	ETF1	1
GO:0097110	scaffold protein binding	1/139	67/18367	0.399443935946981	0.529018570634991	TREM1	1
GO:0019843	rRNA binding	1/139	68/18367	0.404005536652083	0.529018570634991	DDX21	1
GO:0051536	iron-sulfur cluster binding	1/139	68/18367	0.404005536652083	0.529018570634991	GLRX5	1
GO:0051540	metal cluster binding	1/139	68/18367	0.404005536652083	0.529018570634991	GLRX5	1
GO:0005518	collagen binding	1/139	69/18367	0.408532736521221	0.532935562303999	FN1	1
GO:0004857	enzyme inhibitor activity	1/139	70/18367	0.413025793118857	0.53677883974623	ANXA1	1
GO:0031491	nucleosome binding	1/139	71/18367	0.417484962095	0.538246112235908	HMGN1	1
GO:0048029	monosaccharide binding	1/139	71/18367	0.417484962095	0.538246112235908	SLC2A3	1
GO:0008022	protein C-terminus binding	2/139	189/18367	0.41990450446629	0.538246112235908	FN1/MID1IP1	2
GO:0003678	DNA helicase activity	1/139	72/18367	0.421910497199328	0.538246112235908	ANXA1	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	1/139	72/18367	0.421910497199328	0.538246112235908	UQCRH	1
GO:0035064	methylated histone binding	1/139	73/18367	0.426302650295218	0.539879633768031	MORC3	1
GO:0140034	methylation-dependent protein binding	1/139	73/18367	0.426302650295218	0.539879633768031	MORC3	1
GO:0017022	myosin binding	1/139	74/18367	0.430661671373657	0.543416727151487	CXCR4	1
GO:0019003	GDP binding	1/139	75/18367	0.434987808567067	0.546886846278161	RHOB	1
GO:0001221	transcription coregulator binding	1/139	78/18367	0.447771370570183	0.560926590569869	HIF1A	1
GO:0003924	GTPase activity	3/139	337/18367	0.470856781382129	0.585764152874318	GSPT1/TUBA4A/RHOB	3
GO:0005543	phospholipid binding	4/139	466/18367	0.470974635884538	0.585764152874318	SNCA/HMGB1/TLN1/ANXA1	4
GO:0008081	phosphoric diester hydrolase activity	1/139	89/18367	0.492235567795027	0.607849615746883	PDE4B	1
GO:0051117	ATPase binding	1/139	89/18367	0.492235567795027	0.607849615746883	GABARAPL2	1
GO:0000287	magnesium ion binding	2/139	221/18367	0.500240851003052	0.615544593255529	SNCA/MAP3K8	2
GO:0043130	ubiquitin binding	1/139	92/18367	0.503732615755935	0.617650945820881	CXCR4	1
GO:0061134	peptidase regulator activity	2/139	230/18367	0.521539254954169	0.637232822074284	FN1/SNCA	2
GO:0030295	protein kinase activator activity	1/139	101/18367	0.53669576743584	0.65345063614118	HMGB1	1
GO:0015631	tubulin binding	3/139	375/18367	0.542326922132806	0.657010238932467	GABARAPL2/SNCA/PDE4B	3
GO:0031490	chromatin DNA binding	1/139	103/18367	0.543720404033197	0.657010238932467	HMGN1	1
GO:0005525	GTP binding	3/139	377/18367	0.545936291806138	0.657010238932467	GSPT1/TUBA4A/RHOB	3
GO:0004620	phospholipase activity	1/139	104/18367	0.547192965566234	0.657010238932467	PRDX6	1
GO:0042393	histone binding	2/139	244/18367	0.553454620425142	0.662237080301808	SNCA/MORC3	2
GO:0019209	kinase activator activity	1/139	107/18367	0.557453998594134	0.662453895589605	HMGB1	1
GO:0051087	chaperone binding	1/139	107/18367	0.557453998594134	0.662453895589605	FN1	1
GO:0140098	catalytic activity, acting on RNA	3/139	386/18367	0.561974311025587	0.665546368347709	DDX5/DDX21/JMJD6	3
GO:0008047	enzyme activator activity	1/139	110/18367	0.567484142102553	0.666867531876999	CXCL1	1
GO:0047485	protein N-terminus binding	1/139	110/18367	0.567484142102553	0.666867531876999	SNCA	1
GO:0008094	ATP-dependent activity, acting on DNA	1/139	111/18367	0.570777109416336	0.666867531876999	ANXA1	1
GO:0032182	ubiquitin-like protein binding	1/139	111/18367	0.570777109416336	0.666867531876999	CXCR4	1
GO:0003774	cytoskeletal motor activity	1/139	114/18367	0.580507404831211	0.674133360868484	MYH9	1
GO:0019001	guanyl nucleotide binding	3/139	398/18367	0.582824231298401	0.674133360868484	GSPT1/TUBA4A/RHOB	3
GO:0032561	guanyl ribonucleotide binding	3/139	398/18367	0.582824231298401	0.674133360868484	GSPT1/TUBA4A/RHOB	3
GO:0005179	hormone activity	1/139	122/18367	0.605397291044534	0.694809610774417	FBN1	1
GO:0051082	unfolded protein binding	1/139	122/18367	0.605397291044534	0.694809610774417	AHSP	1
GO:0008017	microtubule binding	2/139	271/18367	0.610703583664222	0.694809610774417	GABARAPL2/SNCA	2
GO:0030246	carbohydrate binding	2/139	271/18367	0.610703583664222	0.694809610774417	PRG2/SLC2A3	2
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/139	124/18367	0.611387132766235	0.694809610774417	LDHA	1
GO:0016887	ATP hydrolysis activity	2/139	272/18367	0.612713950711734	0.694809610774417	DDX5/DDX21	2
GO:0009055	electron transfer activity	1/139	126/18367	0.617286696391806	0.69771493044937	UQCRH	1
GO:0140678	molecular function inhibitor activity	1/139	128/18367	0.623097332868513	0.701609869634541	ANXA1	1
GO:0016298	lipase activity	1/139	129/18367	0.625969720100887	0.701609869634541	PRDX6	1
GO:0015078	proton transmembrane transporter activity	1/139	130/18367	0.628820373073032	0.701609869634541	UQCRH	1
GO:0017124	SH3 domain binding	1/139	130/18367	0.628820373073032	0.701609869634541	GPX1	1
GO:0044325	transmembrane transporter binding	1/139	133/18367	0.637243553070068	0.708729208061903	PDE4B	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	1/139	136/18367	0.645476929947485	0.71559263479801	LDHA	1
GO:0051020	GTPase binding	2/139	291/18367	0.649422972140999	0.717674430996582	YBX1/FGD3	2
GO:0099106	ion channel regulator activity	1/139	139/18367	0.653524750322652	0.718867167161567	SGK1	1
GO:0001664	G protein-coupled receptor binding	2/139	295/18367	0.656793348906236	0.718867167161567	CXCL8/CXCL1	2
GO:0030674	protein-macromolecule adaptor activity	2/139	296/18367	0.658616667736911	0.718867167161567	MYH9/BCL3	2
GO:0070851	growth factor receptor binding	1/139	141/18367	0.658788931289274	0.718867167161567	IL1B	1
GO:0016247	channel regulator activity	1/139	145/18367	0.669080238441811	0.727808284449242	SGK1	1
GO:0008528	G protein-coupled peptide receptor activity	1/139	147/18367	0.674109725918441	0.728710513687536	CXCR4	1
GO:0052689	carboxylic ester hydrolase activity	1/139	147/18367	0.674109725918441	0.728710513687536	PRDX6	1
GO:0019842	vitamin binding	1/139	148/18367	0.676595936022576	0.729126676397	ALAS2	1
GO:0001653	peptide receptor activity	1/139	153/18367	0.688747325696914	0.739923597575323	CXCR4	1
GO:0140030	modification-dependent protein binding	1/139	160/18367	0.705001331257399	0.755047722056535	MORC3	1
GO:0004866	endopeptidase inhibitor activity	1/139	180/18367	0.746942648428485	0.797117245621838	SNCA	1
GO:0015399	primary active transmembrane transporter activity	1/139	181/18367	0.74887672067066	0.797117245621838	UQCRH	1
GO:0008514	organic anion transmembrane transporter activity	1/139	185/18367	0.75646734884363	0.802734464980855	SLC2A3	1
GO:0030414	peptidase inhibitor activity	1/139	187/18367	0.760176794233401	0.804211425606678	SNCA	1
GO:0060090	molecular adaptor activity	2/139	369/18367	0.771912920132279	0.812530523994176	MYH9/BCL3	2
GO:0061135	endopeptidase regulator activity	1/139	194/18367	0.772723553078035	0.812530523994176	SNCA	1
GO:0016829	lyase activity	1/139	196/18367	0.776187094803092	0.813706712678771	HMGB1	1
GO:0005085	guanyl-nucleotide exchange factor activity	1/139	223/18367	0.818123204837891	0.855086602646831	FGD3	1
GO:0140097	catalytic activity, acting on DNA	1/139	229/18367	0.82632590218653	0.861066330506684	ANXA1	1
GO:0004842	ubiquitin-protein transferase activity	2/139	433/18367	0.842968549495743	0.875778702619829	RNF149/UBE2S	2
GO:0031267	small GTPase binding	1/139	259/18367	0.862144559650719	0.893027349847163	FGD3	1
GO:0019787	ubiquitin-like protein transferase activity	2/139	458/18367	0.864835842328772	0.893148920500249	RNF149/UBE2S	2
GO:0005096	GTPase activator activity	2/139	462/18367	0.868066069651516	0.893563740846579	JUN/FGD3	2
GO:0022853	active ion transmembrane transporter activity	1/139	267/18367	0.87038773604076	0.893563740846579	UQCRH	1
GO:0035091	phosphatidylinositol binding	1/139	271/18367	0.874323888677119	0.894956900799293	TLN1	1
GO:0030695	GTPase regulator activity	2/139	488/18367	0.887401716140949	0.903015822583312	JUN/FGD3	2
GO:0060589	nucleoside-triphosphatase regulator activity	2/139	488/18367	0.887401716140949	0.903015822583312	JUN/FGD3	2
GO:0061630	ubiquitin protein ligase activity	1/139	304/18367	0.902580933140778	0.915776560818275	RNF149	1
GO:0008509	anion transmembrane transporter activity	1/139	314/18367	0.909825009545336	0.919154899941698	SLC2A3	1
GO:0061659	ubiquitin-like protein ligase activity	1/139	316/18367	0.911208315792347	0.919154899941698	RNF149	1
GO:0042277	peptide binding	1/139	321/18367	0.914575096229939	0.919876980845765	NFKBIA	1
GO:0033218	amide binding	1/139	400/18367	0.95368562287218	0.955794597846827	NFKBIA	1
GO:0022804	active transmembrane transporter activity	1/139	406/18367	0.955794597846827	0.955794597846827	UQCRH	1