ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0042744 hydrogen peroxide catabolic process 8/138 32/18722 6.43448368035555e-11 1.06177620025369e-07 HBA2/HBG1/HBA1/GPX1/SNCA/HBM/HBB/PRDX6 8 GO:0032496 response to lipopolysaccharide 18/138 343/18722 7.63044340821914e-11 1.06177620025369e-07 FOS/PTGS2/TRIB1/CXCL8/NFKBIA/ZFP36/CEBPB/JUND/SNCA/HMGB1/JUN/IL1B/CD55/CXCL1/CHMP5/PDE4B/HMGB2/AKIRIN2 18 GO:0002237 response to molecule of bacterial origin 18/138 363/18722 1.91907419027914e-10 1.78026115718228e-07 FOS/PTGS2/TRIB1/CXCL8/NFKBIA/ZFP36/CEBPB/JUND/SNCA/HMGB1/JUN/IL1B/CD55/CXCL1/CHMP5/PDE4B/HMGB2/AKIRIN2 18 GO:0000302 response to reactive oxygen species 14/138 222/18722 1.03824836610731e-09 7.22361300719163e-07 FOS/DUSP1/HBA2/HBA1/KLF2/GPX1/LDHA/JUN/HBB/HIF1A/ANXA1/PLK3/PPP1R15B/RHOB 14 GO:0030099 myeloid cell differentiation 17/138 381/18722 3.14943701792503e-09 1.64756279647135e-06 FOS/JUNB/TRIB1/NFKBIA/ZFP36/CEBPB/KLF2/HMGB1/FBN1/JUN/MYH9/HIF1A/AHSP/ALAS2/JMJD6/FAM210B/HMGB2 17 GO:0097193 intrinsic apoptotic signaling pathway 15/138 288/18722 3.5520577717672e-09 1.64756279647135e-06 PTGS2/IVNS1ABP/PLAUR/CEBPB/PPP1R15A/BCL2A1/DDIT4/GPX1/DDX5/MCL1/HIF1A/BCL3/UBB/SKIL/MIF 15 GO:0006979 response to oxidative stress 18/138 446/18722 5.07499752434227e-09 2.01767401574922e-06 FOS/PTGS2/DUSP1/HBA2/HBA1/KLF2/GPX1/LDHA/SNCA/MCL1/JUN/HBB/HIF1A/ANXA1/PLK3/PPP1R15B/RHOB/PRDX6 18 GO:0042743 hydrogen peroxide metabolic process 8/138 58/18722 9.98353930658606e-09 3.38634004684885e-06 HBA2/HBG1/HBA1/GPX1/SNCA/HBM/HBB/PRDX6 8 GO:0042542 response to hydrogen peroxide 11/138 146/18722 1.09511535830541e-08 3.38634004684885e-06 DUSP1/HBA2/HBA1/KLF2/GPX1/LDHA/JUN/HBB/ANXA1/PPP1R15B/RHOB 11 GO:0002262 myeloid cell homeostasis 11/138 157/18722 2.3370656937118e-08 6.50405382559994e-06 ZFP36/KLF2/HMGB1/HIF1A/AHSP/ANXA1/ALAS2/JMJD6/FAM210B/PDE4B/HMGB2 11 GO:0071216 cellular response to biotic stimulus 13/138 246/18722 3.49391095016044e-08 8.83959470390591e-06 TRIB1/CXCL8/NFKBIA/ZFP36/CEBPB/HMGB1/IL1B/CD55/CXCL1/CHMP5/PPP1R15B/PDE4B/HMGB2 13 GO:0071222 cellular response to lipopolysaccharide 12/138 209/18722 4.85043159204344e-08 1.12489592672141e-05 TRIB1/CXCL8/NFKBIA/ZFP36/CEBPB/HMGB1/IL1B/CD55/CXCL1/CHMP5/PDE4B/HMGB2 12 GO:0015671 oxygen transport 5/138 15/18722 5.72564573051149e-08 1.22572862061642e-05 HBA2/HBG1/HBA1/HBM/HBB 5 GO:0071219 cellular response to molecule of bacterial origin 12/138 221/18722 8.95160964940949e-08 1.77945211816476e-05 TRIB1/CXCL8/NFKBIA/ZFP36/CEBPB/HMGB1/IL1B/CD55/CXCL1/CHMP5/PDE4B/HMGB2 12 GO:0048872 homeostasis of number of cells 13/138 272/18722 1.13145529991107e-07 2.09922673310168e-05 ZFP36/KLF2/HMGB1/HIF1A/AHSP/ANXA1/ALAS2/JMJD6/FAM210B/SKIL/PDE4B/FAS/HMGB2 13 GO:0015669 gas transport 5/138 20/18722 2.86969511618324e-07 4.99147594271123e-05 HBA2/HBG1/HBA1/HBM/HBB 5 GO:0001819 positive regulation of cytokine production 16/138 467/18722 3.57228344141982e-07 5.84803812792432e-05 EGR1/PTGS2/OSM/CEBPB/HMGB1/RIOK3/DDX21/HIF1A/IL1B/ANXA1/CD55/BCL3/PDE4B/HMGB2/AKIRIN2/MIF 16 GO:0045637 regulation of myeloid cell differentiation 11/138 210/18722 4.51286532918912e-07 6.9773912284074e-05 FOS/TRIB1/NFKBIA/ZFP36/CEBPB/HMGB1/FBN1/JUN/HIF1A/FAM210B/HMGB2 11 GO:1903706 regulation of hemopoiesis 14/138 367/18722 5.65663647100704e-07 8.28548384148032e-05 FOS/TRIB1/NFKBIA/ZFP36/CEBPB/NFKBIZ/HMGB1/FBN1/JUN/HIF1A/ANXA1/EGR3/FAM210B/HMGB2 14 GO:0098869 cellular oxidant detoxification 8/138 101/18722 8.06988001374478e-07 0.000112292380391259 PTGS2/HBA2/HBG1/HBA1/GPX1/HBM/HBB/PRDX6 8 GO:0070555 response to interleukin-1 9/138 143/18722 1.14241379286744e-06 0.000151397027883337 EGR1/CXCL8/CEBPB/KLF2/SNCA/HIF1A/IL1B/ANXA1/IL1R2 9 GO:1990748 cellular detoxification 8/138 116/18722 2.31248285330406e-06 0.000287175169211301 PTGS2/HBA2/HBG1/HBA1/GPX1/HBM/HBB/PRDX6 8 GO:2001233 regulation of apoptotic signaling pathway 13/138 356/18722 2.37334850587852e-06 0.000287175169211301 G0S2/PTGS2/IVNS1ABP/PLAUR/GPX1/MCL1/HIF1A/IL1B/UBB/SKIL/FAS/HMGB2/MIF 13 GO:0070997 neuron death 13/138 361/18722 2.76619365487415e-06 0.000320763205896448 FOS/EGR1/BTG2/CEBPB/DDIT4/GPX1/SNCA/MCL1/JUN/HIF1A/REL/UBB/FAS 13 GO:0030218 erythrocyte differentiation 8/138 120/18722 2.98397803220528e-06 0.000332176434545092 ZFP36/KLF2/HIF1A/AHSP/ALAS2/JMJD6/FAM210B/HMGB2 8 GO:2001242 regulation of intrinsic apoptotic signaling pathway 9/138 164/18722 3.55908685401148e-06 0.000380959181335152 PTGS2/IVNS1ABP/PLAUR/GPX1/MCL1/HIF1A/UBB/SKIL/MIF 9 GO:0097237 cellular response to toxic substance 8/138 124/18722 3.81427023959646e-06 0.000393152373214702 PTGS2/HBA2/HBG1/HBA1/GPX1/HBM/HBB/PRDX6 8 GO:0034109 homotypic cell-cell adhesion 7/138 90/18722 4.55470059284709e-06 0.000445355787724909 FN1/PLAUR/PLEK/TLN1/ACTG1/HBB/MYH9 7 GO:0009612 response to mechanical stimulus 10/138 216/18722 4.64078973913847e-06 0.000445355787724909 FOS/PTGS2/NFKBIA/BTG2/JUND/FOSB/JUN/CXCR4/IL1B/FAS 10 GO:0034101 erythrocyte homeostasis 8/138 129/18722 5.12059202376088e-06 0.000475020253404218 ZFP36/KLF2/HIF1A/AHSP/ALAS2/JMJD6/FAM210B/HMGB2 8 GO:0031349 positive regulation of defense response 11/138 278/18722 6.90049585466622e-06 0.000605469771196631 PTGS2/NFKBIA/OSM/CEBPB/NFKBIZ/SNCA/HMGB1/RIOK3/IL1B/HMGB2/AKIRIN2 11 GO:0062012 regulation of small molecule metabolic process 12/138 334/18722 6.9619233482904e-06 0.000605469771196631 EGR1/PTGS2/PLEK/DDIT4/SNCA/MIDN/HMGB1/HIF1A/IL1B/ANXA1/MID1IP1/IRS2 12 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 7/138 98/18722 8.03116269002356e-06 0.000677294720191987 PTGS2/IVNS1ABP/PLAUR/GPX1/MCL1/HIF1A/MIF 7 GO:0045923 positive regulation of fatty acid metabolic process 5/138 39/18722 9.52300817597134e-06 0.000779486228050831 PTGS2/IL1B/ANXA1/MID1IP1/IRS2 5 GO:0070527 platelet aggregation 6/138 67/18722 9.92068751448736e-06 0.000788836381509095 FN1/PLEK/TLN1/ACTG1/HBB/MYH9 6 GO:0062013 positive regulation of small molecule metabolic process 8/138 143/18722 1.0949314158126e-05 0.000827068741761443 PTGS2/SNCA/HMGB1/HIF1A/IL1B/ANXA1/MID1IP1/IRS2 8 GO:0045639 positive regulation of myeloid cell differentiation 7/138 103/18722 1.11559954703899e-05 0.000827068741761443 FOS/TRIB1/HMGB1/JUN/HIF1A/FAM210B/HMGB2 7 GO:0072593 reactive oxygen species metabolic process 10/138 239/18722 1.1293069416793e-05 0.000827068741761443 HBA2/HBG1/HBA1/DDIT4/GPX1/SNCA/HBM/HBB/HIF1A/PRDX6 10 GO:0051384 response to glucocorticoid 8/138 148/18722 1.40729451787782e-05 0.00100423093416769 FOS/PTGS2/DUSP1/ZFP36/DDIT4/FOSB/HMGB1/ANXA1 8 GO:0032103 positive regulation of response to external stimulus 13/138 427/18722 1.68069618260092e-05 0.00115958397686274 PTGS2/CXCL8/NFKBIA/OSM/CEBPB/NFKBIZ/SNCA/HMGB1/RIOK3/CXCR4/IL1B/HMGB2/AKIRIN2 13 GO:0098754 detoxification 8/138 152/18722 1.70833428140037e-05 0.00115958397686274 PTGS2/HBA2/HBG1/HBA1/GPX1/HBM/HBB/PRDX6 8 GO:0060326 cell chemotaxis 11/138 310/18722 1.91314537891192e-05 0.0012676865689314 DUSP1/CXCL8/TREM1/HMGB1/CXCR4/ANXA1/EGR3/CXCL1/PDE4B/HMGB2/MIF 11 GO:0071347 cellular response to interleukin-1 7/138 113/18722 2.04566354859309e-05 0.00132397247807781 EGR1/CXCL8/CEBPB/KLF2/HIF1A/IL1B/IL1R2 7 GO:0045723 positive regulation of fatty acid biosynthetic process 4/138 23/18722 2.24430562074195e-05 0.00141952330511929 PTGS2/IL1B/ANXA1/MID1IP1 4 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 5/138 47/18722 2.41996112612108e-05 0.0014966115142211 EGR1/CEBPB/KLF2/JUN/HIF1A 5 GO:1901214 regulation of neuron death 11/138 319/18722 2.49063079710879e-05 0.00150683163225082 FOS/EGR1/BTG2/CEBPB/DDIT4/SNCA/MCL1/JUN/HIF1A/REL/UBB 11 GO:0051101 regulation of DNA binding 7/138 118/18722 2.70866464124998e-05 0.00160387525459547 NFKBIA/PLAUR/HMGB1/JUN/BCL3/TAF10/HMGB2 7 GO:0009314 response to radiation 13/138 456/18722 3.33324357846559e-05 0.00191059738861752 FOS/EGR1/PTGS2/DUSP1/JUND/GPX1/JUN/HIF1A/ANXA1/BCL3/HMGN1/PLK3/RHOB 13 GO:0031960 response to corticosteroid 8/138 167/18722 3.3639695308034e-05 0.00191059738861752 FOS/PTGS2/DUSP1/ZFP36/DDIT4/FOSB/HMGB1/ANXA1 8 GO:0009410 response to xenobiotic stimulus 13/138 462/18722 3.81381546687584e-05 0.00212276968886309 FOS/PTGS2/GPX1/LDHA/SNCA/FOSB/RNF149/JUN/CXCR4/IL1B/ANXA1/PLIN2/PDE4B 13 GO:0062197 cellular response to chemical stress 11/138 337/18722 4.11029321955602e-05 0.00224293059412243 FOS/PTGS2/KLF2/GPX1/SNCA/MCL1/JUN/HIF1A/ANXA1/RHOB/FAS 11 GO:2001234 negative regulation of apoptotic signaling pathway 9/138 224/18722 4.31300131350635e-05 0.00229338954040584 PTGS2/IVNS1ABP/PLAUR/GPX1/MCL1/HIF1A/IL1B/HMGB2/MIF 9 GO:0043620 regulation of DNA-templated transcription in response to stress 5/138 53/18722 4.36966508040655e-05 0.00229338954040584 EGR1/CEBPB/KLF2/JUN/HIF1A 5 GO:0001776 leukocyte homeostasis 6/138 87/18722 4.44998329794882e-05 0.00229338954040584 HMGB1/HIF1A/ANXA1/SKIL/PDE4B/FAS 6 GO:0061614 pri-miRNA transcription by RNA polymerase II 5/138 55/18722 5.23494992447966e-05 0.00263120483523318 FOS/EGR1/DDX5/JUN/HIF1A 5 GO:0030595 leukocyte chemotaxis 9/138 230/18722 5.29455518408402e-05 0.00263120483523318 DUSP1/CXCL8/TREM1/HMGB1/CXCR4/ANXA1/CXCL1/PDE4B/MIF 9 GO:0010565 regulation of cellular ketone metabolic process 7/138 133/18722 5.83212300754973e-05 0.00284750847894928 EGR1/PTGS2/SNCA/IL1B/ANXA1/MID1IP1/IRS2 7 GO:0019217 regulation of fatty acid metabolic process 6/138 93/18722 6.47877720975331e-05 0.00310869603012819 PTGS2/SNCA/IL1B/ANXA1/MID1IP1/IRS2 6 GO:0042060 wound healing 12/138 422/18722 6.93482493583338e-05 0.0032711216604109 FN1/PLAUR/PLEK/GPX1/HMGB1/TLN1/ACTG1/HBB/MYH9/CXCR4/HIF1A/ANXA1 12 GO:1903131 mononuclear cell differentiation 12/138 426/18722 7.58578186977221e-05 0.00341961517006683 EGR1/CEBPB/NFIL3/NFKBIZ/HMGB1/JUN/MYH9/IL1B/ANXA1/EGR3/BCL3/JMJD6 12 GO:0001516 prostaglandin biosynthetic process 4/138 31/18722 7.6182587331708e-05 0.00341961517006683 PTGS2/IL1B/ANXA1/MIF 4 GO:0046457 prostanoid biosynthetic process 4/138 31/18722 7.6182587331708e-05 0.00341961517006683 PTGS2/IL1B/ANXA1/MIF 4 GO:1901216 positive regulation of neuron death 6/138 97/18722 8.19934901200864e-05 0.00362202988895556 FOS/EGR1/DDIT4/SNCA/MCL1/JUN 6 GO:0050729 positive regulation of inflammatory response 7/138 142/18722 8.82151038719591e-05 0.00383597865743222 PTGS2/NFKBIA/OSM/CEBPB/NFKBIZ/SNCA/IL1B 7 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 6/138 99/18722 9.18640589991236e-05 0.00393319501837786 BCL2A1/DDIT4/MCL1/BCL3/SKIL/MIF 6 GO:0045936 negative regulation of phosphate metabolic process 12/138 441/18722 0.000105194086651786 0.00434266961043528 DUSP1/TRIB1/PPP1R15A/PLEK/DDIT4/SAMSN1/SNCA/MIDN/SOCS3/IL1B/PPP1R15B/IRS2 12 GO:0031392 regulation of prostaglandin biosynthetic process 3/138 13/18722 0.000106168849340043 0.00434266961043528 PTGS2/IL1B/ANXA1 3 GO:0010563 negative regulation of phosphorus metabolic process 12/138 442/18722 0.000107456534969353 0.00434266961043528 DUSP1/TRIB1/PPP1R15A/PLEK/DDIT4/SAMSN1/SNCA/MIDN/SOCS3/IL1B/PPP1R15B/IRS2 12 GO:0071248 cellular response to metal ion 8/138 197/18722 0.000107669494473602 0.00434266961043528 FOS/JUNB/PTGS2/JUND/SNCA/FOSB/AOC1/JUN 8 GO:0002181 cytoplasmic translation 7/138 148/18722 0.000114330772982097 0.00454546487441679 RPL36A/RPS10/ETF1/GSPT1/RPL17/ZC3H15/RPL7 7 GO:0048821 erythrocyte development 4/138 35/18722 0.000123910227544879 0.00485693187686477 KLF2/ALAS2/JMJD6/FAM210B 4 GO:0050727 regulation of inflammatory response 11/138 386/18722 0.000137693928378025 0.00532225281494505 PTGS2/NFKBIA/OSM/ZFP36/CEBPB/GPX1/NFKBIZ/SNCA/SOCS3/IL1B/ANXA1 11 GO:0009636 response to toxic substance 9/138 262/18722 0.000143049491844632 0.00545351692881659 FOS/PTGS2/HBA2/HBG1/HBA1/GPX1/HBM/HBB/PRDX6 9 GO:1902107 positive regulation of leukocyte differentiation 7/138 157/18722 0.000164991266172222 0.0058861818612511 FOS/TRIB1/NFKBIZ/HMGB1/JUN/ANXA1/EGR3 7 GO:1903708 positive regulation of hemopoiesis 7/138 157/18722 0.000164991266172222 0.0058861818612511 FOS/TRIB1/NFKBIZ/HMGB1/JUN/ANXA1/EGR3 7 GO:0048569 post-embryonic animal organ development 3/138 15/18722 0.000167088885030125 0.0058861818612511 LDHA/FBN1/HMGN1 3 GO:0098760 response to interleukin-7 3/138 15/18722 0.000167088885030125 0.0058861818612511 LSP1/HMGB1/YBX1 3 GO:0098761 cellular response to interleukin-7 3/138 15/18722 0.000167088885030125 0.0058861818612511 LSP1/HMGB1/YBX1 3 GO:2001279 regulation of unsaturated fatty acid biosynthetic process 3/138 15/18722 0.000167088885030125 0.0058861818612511 PTGS2/IL1B/ANXA1 3 GO:0061515 myeloid cell development 5/138 71/18722 0.000178295061324908 0.00620243944584024 KLF2/FBN1/ALAS2/JMJD6/FAM210B 5 GO:0002526 acute inflammatory response 6/138 112/18722 0.000181394941028026 0.00623237186272834 PTGS2/FN1/OSM/CEBPB/TREM1/IL1B 6 GO:0072331 signal transduction by p53 class mediator 7/138 163/18722 0.000207880526057956 0.00692768421145 DDIT4/DDX5/SGK1/BCL3/UBB/PLK3/MIF 7 GO:0045429 positive regulation of nitric oxide biosynthetic process 4/138 40/18722 0.000210192501412303 0.00692768421145 PTGS2/KLF2/HBB/IL1B 4 GO:0007568 aging 10/138 339/18722 0.000211589348894448 0.00692768421145 FOS/PTGS2/JUND/BCL2A1/SERP1/SNCA/JUN/YBX1/MORC3/MIF 10 GO:0048545 response to steroid hormone 10/138 339/18722 0.000211589348894448 0.00692768421145 FOS/PTGS2/DUSP1/ZFP36/DDIT4/DDX5/FOSB/HMGB1/ANXA1/HMGB2 10 GO:0097191 extrinsic apoptotic signaling pathway 8/138 219/18722 0.000222617899834963 0.00720401878186861 G0S2/BCL2A1/GPX1/MCL1/IL1B/SKIL/FAS/HMGB2 8 GO:1902105 regulation of leukocyte differentiation 9/138 279/18722 0.000228705567548548 0.00724179642758676 FOS/TRIB1/CEBPB/NFKBIZ/HMGB1/FBN1/JUN/ANXA1/EGR3 9 GO:0097529 myeloid leukocyte migration 8/138 220/18722 0.000229604207427625 0.00724179642758676 DUSP1/CXCL8/TREM1/HMGB1/ANXA1/CXCL1/PDE4B/MIF 8 GO:1904407 positive regulation of nitric oxide metabolic process 4/138 41/18722 0.000231591765021639 0.00724179642758676 PTGS2/KLF2/HBB/IL1B 4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 5/138 76/18722 0.000245658667081382 0.00747271842798112 DDIT4/DDX5/BCL3/UBB/MIF 5 GO:0001780 neutrophil homeostasis 3/138 17/18722 0.000247032014148136 0.00747271842798112 HMGB1/ANXA1/PDE4B 3 GO:0020027 hemoglobin metabolic process 3/138 17/18722 0.000247032014148136 0.00747271842798112 HIF1A/AHSP/ALAS2 3 GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II 4/138 42/18722 0.000254514827616419 0.00755017187380535 FOS/EGR1/JUN/HIF1A 4 GO:0070482 response to oxygen levels 10/138 347/18722 0.000255018381652067 0.00755017187380535 EGR1/PTGS2/BNIP3L/DDIT4/LDHA/CXCR4/HIF1A/ALAS2/PLK3/FAS 10 GO:0042110 T cell activation 12/138 487/18722 0.000263375161938945 0.00771550605974824 EGR1/CEBPB/NFKBIZ/HMGB1/MYH9/IL1B/ANXA1/EGR3/CD55/BCL3/MAP3K8/JMJD6 12 GO:0071241 cellular response to inorganic substance 8/138 226/18722 0.000275402403192657 0.0079838009175538 FOS/JUNB/PTGS2/JUND/SNCA/FOSB/AOC1/JUN 8 GO:0042088 T-helper 1 type immune response 4/138 43/18722 0.000279024116301804 0.00800540325430847 HMGB1/IL1B/ANXA1/BCL3 4 GO:0050867 positive regulation of cell activation 11/138 420/18722 0.000285297293173356 0.00810186088674948 PLEK/JUND/NFKBIZ/HMGB1/IL1B/ANXA1/EGR3/CD55/MAP3K8/IRS2/MIF 11 GO:0034599 cellular response to oxidative stress 9/138 288/18722 0.000289069610228012 0.00812606793196523 FOS/KLF2/GPX1/SNCA/MCL1/JUN/HIF1A/ANXA1/RHOB 9 GO:0030168 platelet activation 6/138 123/18722 0.000301606284811736 0.00839370290631061 FN1/PLEK/TLN1/ACTG1/HBB/MYH9 6 GO:0001659 temperature homeostasis 7/138 174/18722 0.000309682062183833 0.00851886681632051 G0S2/EGR1/PTGS2/CEBPB/GPX1/CXCR4/IL1B 7 GO:0009791 post-embryonic development 5/138 80/18722 0.000312225804981923 0.00851886681632051 SERP1/CSRNP1/FBN1/HMGN1/MORC3 5 GO:0043534 blood vessel endothelial cell migration 7/138 176/18722 0.000331886539034768 0.00896738095275494 PTGS2/GPX1/HMGB1/MYH9/HIF1A/ANXA1/EGR3 7 GO:0070262 peptidyl-serine dephosphorylation 3/138 19/18722 0.000348240558745277 0.00928283838566368 DUSP1/PPP1R15A/PPP1R15B 3 GO:0001892 embryonic placenta development 5/138 82/18722 0.000350232853214045 0.00928283838566368 JUNB/CEBPB/SOCS3/HIF1A/KRT19 5 GO:0006109 regulation of carbohydrate metabolic process 7/138 178/18722 0.000355350983328952 0.00932963949626862 PLEK/DDIT4/SNCA/MIDN/HMGB1/HIF1A/IRS2 7 GO:0002683 negative regulation of immune system process 11/138 434/18722 0.000376653503221799 0.00970580277283581 DUSP1/TRIB1/CEBPB/GPX1/SAMSN1/HMGB1/RIOK3/FBN1/ANXA1/CD55/MIF 11 GO:0008380 RNA splicing 11/138 434/18722 0.000376653503221799 0.00970580277283581 IVNS1ABP/DDX5/YBX1/HNRNPA3/SRSF2/HNRNPA2B1/HNRNPH2/C9orf78/JMJD6/PRDX6/SAP18 11 GO:0045766 positive regulation of angiogenesis 7/138 181/18722 0.000393023745159386 0.00987283802410941 CXCL8/HMGB1/CXCR4/HIF1A/IL1B/LRG1/RHOB 7 GO:1904018 positive regulation of vasculature development 7/138 181/18722 0.000393023745159386 0.00987283802410941 CXCL8/HMGB1/CXCR4/HIF1A/IL1B/LRG1/RHOB 7 GO:0045646 regulation of erythrocyte differentiation 4/138 47/18722 0.000394189888346508 0.00987283802410941 ZFP36/HIF1A/FAM210B/HMGB2 4 GO:0001701 in utero embryonic development 10/138 367/18722 0.00039732585652183 0.00987283802410941 JUNB/CEBPB/KLF2/SOCS3/MYH9/YBX1/HIF1A/BTF3/KRT19/SKIL 10 GO:0050900 leukocyte migration 10/138 369/18722 0.000414623237329629 0.0102114731813129 DUSP1/CXCL8/TREM1/HMGB1/MYH9/CXCR4/ANXA1/CXCL1/PDE4B/MIF 10 GO:0046683 response to organophosphorus 6/138 131/18722 0.000422797399939104 0.0103214488072853 FOS/PTGS2/DUSP1/LDHA/FOSB/JUN 6 GO:0010038 response to metal ion 10/138 373/18722 0.000451104609695687 0.0107365548611066 FOS/JUNB/PTGS2/DUSP1/JUND/SNCA/FOSB/AOC1/JUN/HIF1A 10 GO:0001666 response to hypoxia 9/138 307/18722 0.000460439679797231 0.0107365548611066 EGR1/PTGS2/BNIP3L/DDIT4/LDHA/CXCR4/HIF1A/ALAS2/PLK3 9 GO:0006692 prostanoid metabolic process 4/138 49/18722 0.000462948826206537 0.0107365548611066 PTGS2/IL1B/ANXA1/MIF 4 GO:0006693 prostaglandin metabolic process 4/138 49/18722 0.000462948826206537 0.0107365548611066 PTGS2/IL1B/ANXA1/MIF 4 GO:0006953 acute-phase response 4/138 49/18722 0.000462948826206537 0.0107365548611066 PTGS2/FN1/CEBPB/IL1B 4 GO:0042304 regulation of fatty acid biosynthetic process 4/138 49/18722 0.000462948826206537 0.0107365548611066 PTGS2/IL1B/ANXA1/MID1IP1 4 GO:0051402 neuron apoptotic process 8/138 246/18722 0.00048501693535636 0.0111553895131963 BTG2/CEBPB/GPX1/SNCA/MCL1/JUN/HIF1A/FAS 8 GO:0050671 positive regulation of lymphocyte proliferation 6/138 137/18722 0.000536354108866213 0.012214707340713 HMGB1/IL1B/ANXA1/CD55/IRS2/MIF 6 GO:0006636 unsaturated fatty acid biosynthetic process 4/138 51/18722 0.000539852318687638 0.012214707340713 PTGS2/IL1B/ANXA1/MIF 4 GO:0032946 positive regulation of mononuclear cell proliferation 6/138 138/18722 0.00055738478094482 0.0125096923013664 HMGB1/IL1B/ANXA1/CD55/IRS2/MIF 6 GO:0042326 negative regulation of phosphorylation 10/138 385/18722 0.000576936470115166 0.0128449135706441 DUSP1/TRIB1/DDIT4/SAMSN1/SNCA/MIDN/SOCS3/IL1B/PPP1R15B/IRS2 10 GO:0051591 response to cAMP 5/138 93/18722 0.000625362935039313 0.0135981465121461 FOS/DUSP1/LDHA/FOSB/JUN 5 GO:1901796 regulation of signal transduction by p53 class mediator 5/138 93/18722 0.000625362935039313 0.0135981465121461 DDX5/SGK1/UBB/PLK3/MIF 5 GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 4/138 53/18722 0.000625426788916531 0.0135981465121461 CXCL8/PLEK/SNCA/PDE4B 4 GO:0030217 T cell differentiation 8/138 257/18722 0.000646567045734353 0.0138805263631171 EGR1/NFKBIZ/HMGB1/IL1B/ANXA1/EGR3/BCL3/JMJD6 8 GO:0036293 response to decreased oxygen levels 9/138 322/18722 0.000648389661230765 0.0138805263631171 EGR1/PTGS2/BNIP3L/DDIT4/LDHA/CXCR4/HIF1A/ALAS2/PLK3 9 GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II 4/138 54/18722 0.000671631162412335 0.0142683169846834 FOS/EGR1/JUN/HIF1A 4 GO:0001890 placenta development 6/138 144/18722 0.000697382418507184 0.0147031459901931 JUNB/PTGS2/CEBPB/SOCS3/HIF1A/KRT19 6 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress 3/138 24/18722 0.000708039946493264 0.0148156027901561 CEBPB/KLF2/HIF1A 3 GO:0010675 regulation of cellular carbohydrate metabolic process 6/138 146/18722 0.000749634991478063 0.0153304891281946 PLEK/DDIT4/SNCA/MIDN/HMGB1/IRS2 6 GO:0019221 cytokine-mediated signaling pathway 11/138 472/18722 0.000756294299082852 0.0153304891281946 EGR1/CXCL8/NFKBIA/OSM/CXCR4/HIF1A/IL1B/CXCL1/ZC3H15/FAS/IL1R2 11 GO:1990868 response to chemokine 5/138 97/18722 0.000757483036565783 0.0153304891281946 DUSP1/CXCL8/CXCR4/HIF1A/CXCL1 5 GO:1990869 cellular response to chemokine 5/138 97/18722 0.000757483036565783 0.0153304891281946 DUSP1/CXCL8/CXCR4/HIF1A/CXCL1 5 GO:0032608 interferon-beta production 4/138 56/18722 0.000771206783308387 0.0153304891281946 HMGB1/RIOK3/REL/HMGB2 4 GO:0032648 regulation of interferon-beta production 4/138 56/18722 0.000771206783308387 0.0153304891281946 HMGB1/RIOK3/REL/HMGB2 4 GO:0046456 icosanoid biosynthetic process 4/138 56/18722 0.000771206783308387 0.0153304891281946 PTGS2/IL1B/ANXA1/MIF 4 GO:0033622 integrin activation 3/138 25/18722 0.00080026856605622 0.0156639238997964 FN1/PLEK/TLN1 3 GO:0014074 response to purine-containing compound 6/138 148/18722 0.000804865654930252 0.0156639238997964 FOS/PTGS2/DUSP1/LDHA/FOSB/JUN 6 GO:0043484 regulation of RNA splicing 6/138 148/18722 0.000804865654930252 0.0156639238997964 DDX5/SRSF2/HNRNPH2/JMJD6/PRDX6/SAP18 6 GO:0032602 chemokine production 5/138 99/18722 0.000830863550542501 0.0160575920913874 EGR1/TREM1/HMGB1/HIF1A/IL1B 5 GO:0070665 positive regulation of leukocyte proliferation 6/138 150/18722 0.00086318814728053 0.0165672594060808 HMGB1/IL1B/ANXA1/CD55/IRS2/MIF 6 GO:2001236 regulation of extrinsic apoptotic signaling pathway 6/138 151/18722 0.00089354488476144 0.0169749909112748 G0S2/GPX1/MCL1/IL1B/SKIL/HMGB2 6 GO:0002573 myeloid leukocyte differentiation 7/138 208/18722 0.000896630853020981 0.0169749909112748 FOS/JUNB/TRIB1/CEBPB/FBN1/JUN/MYH9 7 GO:0048024 regulation of mRNA splicing, via spliceosome 5/138 101/18722 0.000909419162946276 0.0171007670978344 DDX5/SRSF2/JMJD6/PRDX6/SAP18 5 GO:0002696 positive regulation of leukocyte activation 10/138 409/18722 0.000916553194786257 0.0171192452422158 JUND/NFKBIZ/HMGB1/IL1B/ANXA1/EGR3/CD55/MAP3K8/IRS2/MIF 10 GO:0090303 positive regulation of wound healing 4/138 59/18722 0.000939488789053003 0.0174306486662301 HMGB1/ACTG1/CXCR4/ANXA1 4 GO:0035710 CD4-positive, alpha-beta T cell activation 5/138 102/18722 0.000950707771340336 0.0175219849512593 NFKBIZ/HMGB1/ANXA1/CD55/BCL3 5 GO:0042180 cellular ketone metabolic process 7/138 211/18722 0.000974728216291949 0.0178465041180296 EGR1/PTGS2/SNCA/IL1B/ANXA1/MID1IP1/IRS2 7 GO:0031663 lipopolysaccharide-mediated signaling pathway 4/138 60/18722 0.00100089527325008 0.0181572294406566 TRIB1/NFKBIA/IL1B/CD55 4 GO:0043434 response to peptide hormone 10/138 414/18722 0.00100474787418653 0.0181572294406566 EGR1/PTGS2/BTG2/PTPRE/JUND/FBN1/SOCS3/IL1B/ANXA1/IRS2 10 GO:0043542 endothelial cell migration 8/138 279/18722 0.00109968420392135 0.0194479910664241 PTGS2/GPX1/HMGB1/MYH9/HIF1A/ANXA1/EGR3/RHOB 8 GO:0050870 positive regulation of T cell activation 7/138 216/18722 0.00111671027867754 0.0194479910664241 NFKBIZ/HMGB1/IL1B/ANXA1/EGR3/CD55/MAP3K8 7 GO:0002675 positive regulation of acute inflammatory response 3/138 28/18722 0.00112160133137819 0.0194479910664241 PTGS2/OSM/IL1B 3 GO:0010575 positive regulation of vascular endothelial growth factor production 3/138 28/18722 0.00112160133137819 0.0194479910664241 PTGS2/HIF1A/IL1B 3 GO:0042116 macrophage activation 5/138 106/18722 0.00112993120984205 0.0194479910664241 JUND/SNCA/HMGB1/JMJD6/MIF 5 GO:0032623 interleukin-2 production 4/138 62/18722 0.0011320785313549 0.0194479910664241 ZFP36/IL1B/ANXA1/PDE4B 4 GO:0032663 regulation of interleukin-2 production 4/138 62/18722 0.0011320785313549 0.0194479910664241 ZFP36/IL1B/ANXA1/PDE4B 4 GO:0045428 regulation of nitric oxide biosynthetic process 4/138 62/18722 0.0011320785313549 0.0194479910664241 PTGS2/KLF2/HBB/IL1B 4 GO:0007596 blood coagulation 7/138 217/18722 0.00114696167964874 0.0195827874506899 FN1/PLAUR/PLEK/TLN1/ACTG1/HBB/MYH9 7 GO:0031532 actin cytoskeleton reorganization 5/138 107/18722 0.00117839813570663 0.0199968415345827 PLEK/MYH9/GPR65/ANXA1/PHACTR1 5 GO:2001020 regulation of response to DNA damage stimulus 7/138 219/18722 0.00120939384935427 0.0203984429257753 IER3/DDX5/HMGB1/MCL1/PPP1R10/SKIL/MIF 7 GO:0022409 positive regulation of cell-cell adhesion 8/138 284/18722 0.00123161186895973 0.0206480471765959 PLAUR/NFKBIZ/HMGB1/IL1B/ANXA1/EGR3/CD55/MAP3K8 8 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 3/138 29/18722 0.00124430534639945 0.0207359387965848 GPX1/MCL1/HIF1A 3 GO:0031331 positive regulation of cellular catabolic process 10/138 427/18722 0.00126710802869407 0.0209902478800929 TRIB1/BTG2/ZFP36/BNIP3L/SNCA/HMGB1/HIF1A/IL1B/PLK3/IRS2 10 GO:0080164 regulation of nitric oxide metabolic process 4/138 64/18722 0.00127486798954205 0.0209938320408019 PTGS2/KLF2/HBB/IL1B 4 GO:0007599 hemostasis 7/138 222/18722 0.00130800768986261 0.0212876339233196 FN1/PLAUR/PLEK/TLN1/ACTG1/HBB/MYH9 7 GO:0050817 coagulation 7/138 222/18722 0.00130800768986261 0.0212876339233196 FN1/PLAUR/PLEK/TLN1/ACTG1/HBB/MYH9 7 GO:0001818 negative regulation of cytokine production 9/138 357/18722 0.00133741330612636 0.0214812924846361 FN1/ZFP36/KLF2/HMGB1/SRGN/ANXA1/BCL3/REL/IL1R2 9 GO:1903311 regulation of mRNA metabolic process 8/138 288/18722 0.00134599825604495 0.0214812924846361 BTG2/ZFP36/DDX5/YBX1/SRSF2/JMJD6/PRDX6/SAP18 8 GO:0038034 signal transduction in absence of ligand 4/138 65/18722 0.00135078195645394 0.0214812924846361 BCL2A1/MCL1/IL1B/FAS 4 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 4/138 65/18722 0.00135078195645394 0.0214812924846361 BCL2A1/MCL1/IL1B/FAS 4 GO:0070498 interleukin-1-mediated signaling pathway 3/138 30/18722 0.00137514674318329 0.0217445078765857 EGR1/IL1B/IL1R2 3 GO:0001938 positive regulation of endothelial cell proliferation 5/138 111/18722 0.0013877839848539 0.021820354970895 HMGB1/HIF1A/EGR3/LRG1/HMGB2 5 GO:0050670 regulation of lymphocyte proliferation 7/138 225/18722 0.00141281116422412 0.022089064438403 CEBPB/HMGB1/IL1B/ANXA1/CD55/IRS2/MIF 7 GO:0042093 T-helper cell differentiation 4/138 66/18722 0.00142979756124475 0.0221062589608008 NFKBIZ/HMGB1/ANXA1/BCL3 4 GO:0050918 positive chemotaxis 4/138 66/18722 0.00142979756124475 0.0221062589608008 CXCL8/HMGB1/HMGB2/MIF 4 GO:0000956 nuclear-transcribed mRNA catabolic process 5/138 112/18722 0.00144415730465885 0.0222049159053347 BTG2/ZFP36/DDX5/ETF1/GSPT1 5 GO:0051251 positive regulation of lymphocyte activation 9/138 362/18722 0.00147185992081853 0.0225065173606482 NFKBIZ/HMGB1/IL1B/ANXA1/EGR3/CD55/MAP3K8/IRS2/MIF 9 GO:0032944 regulation of mononuclear cell proliferation 7/138 227/18722 0.00148624922640892 0.0226023584540766 CEBPB/HMGB1/IL1B/ANXA1/CD55/IRS2/MIF 7 GO:0035914 skeletal muscle cell differentiation 4/138 67/18722 0.00151198124452953 0.0227451016406793 FOS/EGR1/BTG2/DDX5 4 GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 4/138 67/18722 0.00151198124452953 0.0227451016406793 NFKBIZ/HMGB1/ANXA1/CD55 4 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 4/138 68/18722 0.00159739928583368 0.0239008721100814 NFKBIZ/HMGB1/ANXA1/BCL3 4 GO:0022411 cellular component disassembly 10/138 443/18722 0.00166425904548175 0.024704995456178 BNIP3L/PLEK/GABARAPL2/DDIT4/HIF1A/ETF1/GSPT1/CHMP5/PLK3/MID1IP1 10 GO:0002287 alpha-beta T cell activation involved in immune response 4/138 69/18722 0.00168611778258572 0.024704995456178 NFKBIZ/HMGB1/ANXA1/BCL3 4 GO:0002293 alpha-beta T cell differentiation involved in immune response 4/138 69/18722 0.00168611778258572 0.024704995456178 NFKBIZ/HMGB1/ANXA1/BCL3 4 GO:0033559 unsaturated fatty acid metabolic process 5/138 116/18722 0.00168665078572541 0.024704995456178 PTGS2/GPX1/IL1B/ANXA1/MIF 5 GO:0045862 positive regulation of proteolysis 9/138 372/18722 0.00177341575938002 0.0258398746510712 TRIB1/FN1/SNCA/HMGB1/MYH9/IL1B/PLK3/FAS/AKIRIN2 9 GO:0045648 positive regulation of erythrocyte differentiation 3/138 33/18722 0.00181842695449021 0.0263577198663867 HIF1A/FAM210B/HMGB2 3 GO:0030098 lymphocyte differentiation 9/138 374/18722 0.00183928647228685 0.026521939131473 EGR1/NFIL3/NFKBIZ/HMGB1/IL1B/ANXA1/EGR3/BCL3/JMJD6 9 GO:0032722 positive regulation of chemokine production 4/138 71/18722 0.00187371949940253 0.0268791823032848 EGR1/HMGB1/HIF1A/IL1B 4 GO:0002761 regulation of myeloid leukocyte differentiation 5/138 120/18722 0.0019577889363828 0.0275757507049507 FOS/TRIB1/CEBPB/FBN1/JUN 5 GO:0071774 response to fibroblast growth factor 5/138 120/18722 0.0019577889363828 0.0275757507049507 IER2/CXCL8/ZFP36/SNCA/EGR3 5 GO:0030330 DNA damage response, signal transduction by p53 class mediator 4/138 72/18722 0.00197273382230553 0.0275757507049507 DDX5/BCL3/PLK3/MIF 4 GO:1903036 positive regulation of response to wounding 4/138 72/18722 0.00197273382230553 0.0275757507049507 HMGB1/ACTG1/CXCR4/ANXA1 4 GO:0010922 positive regulation of phosphatase activity 3/138 34/18722 0.00198372207292585 0.0275757507049507 PPP1R15A/PLEK/PPP1R15B 3 GO:0032743 positive regulation of interleukin-2 production 3/138 34/18722 0.00198372207292585 0.0275757507049507 IL1B/ANXA1/PDE4B 3 GO:1903039 positive regulation of leukocyte cell-cell adhesion 7/138 239/18722 0.0019916370433687 0.0275757507049507 NFKBIZ/HMGB1/IL1B/ANXA1/EGR3/CD55/MAP3K8 7 GO:0071453 cellular response to oxygen levels 6/138 177/18722 0.00201432422588433 0.0277518035675054 EGR1/PTGS2/BNIP3L/HIF1A/PLK3/FAS 6 GO:0046627 negative regulation of insulin receptor signaling pathway 3/138 35/18722 0.00215807943343032 0.0295858870110176 PTPRE/SOCS3/IL1B 3 GO:0006690 icosanoid metabolic process 5/138 123/18722 0.00218110879144288 0.0297550282675762 PTGS2/GPX1/IL1B/ANXA1/MIF 5 GO:0070663 regulation of leukocyte proliferation 7/138 245/18722 0.00228970993932822 0.0308067585479843 CEBPB/HMGB1/IL1B/ANXA1/CD55/IRS2/MIF 7 GO:0002292 T cell differentiation involved in immune response 4/138 75/18722 0.00229141179282528 0.0308067585479843 NFKBIZ/HMGB1/ANXA1/BCL3 4 GO:0045913 positive regulation of carbohydrate metabolic process 4/138 75/18722 0.00229141179282528 0.0308067585479843 SNCA/HMGB1/HIF1A/IRS2 4 GO:0031340 positive regulation of vesicle fusion 2/138 10/18722 0.00233505093316316 0.031158346683826 SNCA/ANXA1 2 GO:0071621 granulocyte chemotaxis 5/138 125/18722 0.00233995488929918 0.031158346683826 CXCL8/TREM1/ANXA1/CXCL1/PDE4B 5 GO:0002819 regulation of adaptive immune response 6/138 183/18722 0.00238062657479216 0.0315489702745075 NFKBIZ/SAMSN1/HMGB1/IL1B/ANXA1/CD55 6 GO:0006809 nitric oxide biosynthetic process 4/138 76/18722 0.00240506474425549 0.0315721470908634 PTGS2/KLF2/HBB/IL1B 4 GO:0043536 positive regulation of blood vessel endothelial cell migration 4/138 76/18722 0.00240506474425549 0.0315721470908634 PTGS2/HMGB1/HIF1A/ANXA1 4 GO:2001235 positive regulation of apoptotic signaling pathway 5/138 126/18722 0.00242245988382602 0.0316512012051071 G0S2/MCL1/UBB/SKIL/FAS 5 GO:0006417 regulation of translation 10/138 468/18722 0.00248226798014121 0.0322810831249205 BTG2/ZFP36/PPP1R15A/EIF1/SERP1/YBX1/ETF1/GSPT1/BCL3/PPP1R15B 10 GO:0046883 regulation of hormone secretion 7/138 249/18722 0.00250680641041962 0.032381031075205 OSM/SERP1/MIDN/HIF1A/IL1B/ANXA1/IRS2 7 GO:0002040 sprouting angiogenesis 6/138 185/18722 0.00251322411507161 0.032381031075205 PTGS2/KLF2/HMGB1/ANXA1/EGR3/JMJD6 6 GO:1900077 negative regulation of cellular response to insulin stimulus 3/138 37/18722 0.00253465142899943 0.0325066125663844 PTPRE/SOCS3/IL1B 3 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 8/138 320/18722 0.00259699683711374 0.0328520099894888 DDX5/HNRNPA3/SRSF2/HNRNPA2B1/C9orf78/JMJD6/PRDX6/SAP18 8 GO:0000398 mRNA splicing, via spliceosome 8/138 320/18722 0.00259699683711374 0.0328520099894888 DDX5/HNRNPA3/SRSF2/HNRNPA2B1/C9orf78/JMJD6/PRDX6/SAP18 8 GO:0009416 response to light stimulus 8/138 320/18722 0.00259699683711374 0.0328520099894888 FOS/PTGS2/DUSP1/JUND/GPX1/HIF1A/BCL3/HMGN1 8 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 4/138 78/18722 0.00264389524654 0.0332939387833521 PTGS2/PLAUR/GPX1/SNCA 4 GO:0043467 regulation of generation of precursor metabolites and energy 5/138 130/18722 0.0027737445805022 0.0345163909458354 DDIT4/SNCA/HMGB1/HIF1A/IRS2 5 GO:0000375 RNA splicing, via transesterification reactions 8/138 324/18722 0.00280223703582196 0.0345163909458354 DDX5/HNRNPA3/SRSF2/HNRNPA2B1/C9orf78/JMJD6/PRDX6/SAP18 8 GO:0001660 fever generation 2/138 11/18722 0.00284019170916145 0.0345163909458354 PTGS2/IL1B 2 GO:0006449 regulation of translational termination 2/138 11/18722 0.00284019170916145 0.0345163909458354 ETF1/GSPT1 2 GO:0031652 positive regulation of heat generation 2/138 11/18722 0.00284019170916145 0.0345163909458354 PTGS2/IL1B 2 GO:0033483 gas homeostasis 2/138 11/18722 0.00284019170916145 0.0345163909458354 HIF1A/ALAS2 2 GO:0036490 regulation of translation in response to endoplasmic reticulum stress 2/138 11/18722 0.00284019170916145 0.0345163909458354 PPP1R15A/PPP1R15B 2 GO:1903897 regulation of PERK-mediated unfolded protein response 2/138 11/18722 0.00284019170916145 0.0345163909458354 PPP1R15A/PPP1R15B 2 GO:0007611 learning or memory 7/138 255/18722 0.00286179563396626 0.0346277271709917 FOS/PTGS2/BTG2/CEBPB/JUN/HIF1A/SGK1 7 GO:0048145 regulation of fibroblast proliferation 4/138 80/18722 0.00289851404505626 0.034901496461625 FN1/FTH1/MORC3/MIF 4 GO:0051235 maintenance of location 8/138 326/18722 0.00290950311861193 0.034901496461625 NFKBIA/SNCA/FBN1/SRGN/IL1B/FTH1/PLIN2/MORC3 8 GO:0032728 positive regulation of interferon-beta production 3/138 39/18722 0.00294943297951159 0.0350780853930801 HMGB1/RIOK3/HMGB2 3 GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 3/138 39/18722 0.00294943297951159 0.0350780853930801 NFKBIZ/ANXA1/CD55 3 GO:0046209 nitric oxide metabolic process 4/138 81/18722 0.00303190094475989 0.035753306479944 PTGS2/KLF2/HBB/IL1B 4 GO:0048144 fibroblast proliferation 4/138 81/18722 0.00303190094475989 0.035753306479944 FN1/FTH1/MORC3/MIF 4 GO:0010595 positive regulation of endothelial cell migration 5/138 133/18722 0.00306039979065677 0.0359370996514675 PTGS2/HMGB1/HIF1A/ANXA1/RHOB 5 GO:0050863 regulation of T cell activation 8/138 329/18722 0.00307638747123162 0.0359730518169647 CEBPB/NFKBIZ/HMGB1/IL1B/ANXA1/EGR3/CD55/MAP3K8 8 GO:0046889 positive regulation of lipid biosynthetic process 4/138 82/18722 0.00316942238535198 0.0367520937434773 PTGS2/IL1B/ANXA1/MID1IP1 4 GO:2001057 reactive nitrogen species metabolic process 4/138 82/18722 0.00316942238535198 0.0367520937434773 PTGS2/KLF2/HBB/IL1B 4 GO:0030073 insulin secretion 6/138 195/18722 0.00326125842615695 0.0376600921161609 SERP1/MIDN/HIF1A/IL1B/ANXA1/IRS2 6 GO:0001503 ossification 9/138 408/18722 0.00329197775206743 0.0378577441487754 JUNB/PTGS2/CEBPB/JUND/DDX5/SRGN/DDX21/HIF1A/HEMGN 9 GO:0043367 CD4-positive, alpha-beta T cell differentiation 4/138 83/18722 0.00331113999680888 0.0379214099223009 NFKBIZ/HMGB1/ANXA1/BCL3 4 GO:0009886 post-embryonic animal morphogenesis 2/138 12/18722 0.00339180781228715 0.0383494496074497 FBN1/HMGN1 2 GO:0070493 thrombin-activated receptor signaling pathway 2/138 12/18722 0.00339180781228715 0.0383494496074497 PLEK/SNCA 2 GO:0071872 cellular response to epinephrine stimulus 2/138 12/18722 0.00339180781228715 0.0383494496074497 SNCA/PDE4B 2 GO:0071634 regulation of transforming growth factor beta production 3/138 41/18722 0.00340363422674814 0.0383494496074497 PTGS2/FN1/HIF1A 3 GO:0050684 regulation of mRNA processing 5/138 137/18722 0.00347511381248213 0.0389969425005555 DDX5/SRSF2/JMJD6/PRDX6/SAP18 5 GO:1903037 regulation of leukocyte cell-cell adhesion 8/138 336/18722 0.00349483853253222 0.0390607856868962 CEBPB/NFKBIZ/HMGB1/IL1B/ANXA1/EGR3/CD55/MAP3K8 8 GO:0009896 positive regulation of catabolic process 10/138 492/18722 0.00354543016267116 0.0394677285708554 TRIB1/BTG2/ZFP36/BNIP3L/SNCA/HMGB1/HIF1A/IL1B/PLK3/IRS2 10 GO:0071277 cellular response to calcium ion 4/138 85/18722 0.00360740805399298 0.0399976757540338 FOS/JUNB/JUND/FOSB 4 GO:0010677 negative regulation of cellular carbohydrate metabolic process 3/138 42/18722 0.0036458741805275 0.0402637612873335 PLEK/DDIT4/MIDN 3 GO:0015908 fatty acid transport 4/138 86/18722 0.00376207952182147 0.0410632020483142 IL1B/ANXA1/PLIN2/IRS2 4 GO:2000117 negative regulation of cysteine-type endopeptidase activity 4/138 86/18722 0.00376207952182147 0.0410632020483142 PTGS2/PLAUR/GPX1/SNCA 4 GO:0051348 negative regulation of transferase activity 7/138 268/18722 0.00376252839465329 0.0410632020483142 DUSP1/TRIB1/ZFP36/SNCA/MIDN/IL1B/IRS2 7 GO:0001933 negative regulation of protein phosphorylation 8/138 342/18722 0.00388758142704209 0.0418888556913651 DUSP1/TRIB1/DDIT4/SAMSN1/SNCA/SOCS3/IL1B/PPP1R15B 8 GO:0045765 regulation of angiogenesis 8/138 342/18722 0.00388758142704209 0.0418888556913651 CXCL8/KLF2/HMGB1/CXCR4/HIF1A/IL1B/LRG1/RHOB 8 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 3/138 43/18722 0.00389838793534443 0.0418888556913651 DDIT4/BCL3/MIF 3 GO:0071604 transforming growth factor beta production 3/138 43/18722 0.00389838793534443 0.0418888556913651 PTGS2/FN1/HIF1A 3 GO:0032352 positive regulation of hormone metabolic process 2/138 13/18722 0.00398919671464117 0.042052782033509 EGR1/HIF1A 2 GO:0042541 hemoglobin biosynthetic process 2/138 13/18722 0.00398919671464117 0.042052782033509 HIF1A/ALAS2 2 GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 2/138 13/18722 0.00398919671464117 0.042052782033509 BTG2/ZFP36 2 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 2/138 13/18722 0.00398919671464117 0.042052782033509 EGR1/HIF1A 2 GO:2001198 regulation of dendritic cell differentiation 2/138 13/18722 0.00398919671464117 0.042052782033509 CEBPB/HMGB1 2 GO:0070098 chemokine-mediated signaling pathway 4/138 88/18722 0.00408479634203773 0.0428980687543057 CXCL8/CXCR4/HIF1A/CXCL1 4 GO:0038061 NIK/NF-kappaB signaling 5/138 143/18722 0.00417085079133026 0.0436371344070381 NFKBIA/HMGB1/IL1B/BCL3/REL 5 GO:0048608 reproductive structure development 9/138 424/18722 0.00423241406148148 0.0441153870153668 JUNB/PTGS2/CEBPB/SOCS3/HIF1A/ANXA1/UBB/KRT19/HMGB2 9 GO:0007612 learning 5/138 144/18722 0.00429579569682749 0.0444431205363231 FOS/PTGS2/BTG2/JUN/HIF1A 5 GO:0033135 regulation of peptidyl-serine phosphorylation 5/138 144/18722 0.00429579569682749 0.0444431205363231 PTGS2/OSM/DDIT4/SNCA/MIF 5 GO:1901342 regulation of vasculature development 8/138 348/18722 0.00431366687076773 0.0444627218568393 CXCL8/KLF2/HMGB1/CXCR4/HIF1A/IL1B/LRG1/RHOB 8 GO:0032392 DNA geometric change 4/138 90/18722 0.00442573793697672 0.0450434842198439 HMGB1/ANXA1/HNRNPA2B1/HMGB2 4 GO:0045638 negative regulation of myeloid cell differentiation 4/138 90/18722 0.00442573793697672 0.0450434842198439 TRIB1/NFKBIA/ZFP36/FBN1 4 GO:0061458 reproductive system development 9/138 427/18722 0.00443005716099259 0.0450434842198439 JUNB/PTGS2/CEBPB/SOCS3/HIF1A/ANXA1/UBB/KRT19/HMGB2 9 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 3/138 45/18722 0.00443475194977982 0.0450434842198439 GPX1/MCL1/HIF1A 3 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 6/138 209/18722 0.00457273009766927 0.046276028588413 PTGS2/PLAUR/GPX1/SNCA/HMGB1/FAS 6 GO:0031650 regulation of heat generation 2/138 14/18722 0.00463166358924908 0.0463666178736698 PTGS2/IL1B 2 GO:0043249 erythrocyte maturation 2/138 14/18722 0.00463166358924908 0.0463666178736698 KLF2/FAM210B 2 GO:0043558 regulation of translational initiation in response to stress 2/138 14/18722 0.00463166358924908 0.0463666178736698 PPP1R15A/PPP1R15B 2 GO:1903531 negative regulation of secretion by cell 5/138 147/18722 0.00468665115367682 0.046748925307106 OSM/SNCA/MIDN/IL1B/ANXA1 5 GO:0097530 granulocyte migration 5/138 148/18722 0.00482237791936725 0.0479309919628538 CXCL8/TREM1/ANXA1/CXCL1/PDE4B 5 GO:0043523 regulation of neuron apoptotic process 6/138 212/18722 0.0048980310815543 0.0485096814945395 BTG2/CEBPB/SNCA/MCL1/JUN/HIF1A 6 GO:0045834 positive regulation of lipid metabolic process 5/138 149/18722 0.00496087599850057 0.0487253831815063 PTGS2/IL1B/ANXA1/MID1IP1/IRS2 5 GO:0051592 response to calcium ion 5/138 149/18722 0.00496087599850057 0.0487253831815063 FOS/JUNB/DUSP1/JUND/FOSB 5 GO:0045185 maintenance of protein location 4/138 93/18722 0.00497233518632691 0.0487253831815063 NFKBIA/FBN1/SRGN/MORC3 4 GO:0010631 epithelial cell migration 8/138 357/18722 0.00501931573195018 0.0490131778316398 PTGS2/GPX1/HMGB1/MYH9/HIF1A/ANXA1/EGR3/RHOB 8 GO:0045785 positive regulation of cell adhesion 9/138 437/18722 0.00514143953843281 0.0496779828553007 FN1/PLAUR/NFKBIZ/HMGB1/IL1B/ANXA1/EGR3/CD55/MAP3K8 9 GO:0050673 epithelial cell proliferation 9/138 437/18722 0.00514143953843281 0.0496779828553007 ZFP36/CEBPB/GPX1/HMGB1/HIF1A/EGR3/LRG1/HMGN1/HMGB2 9 GO:0030316 osteoclast differentiation 4/138 94/18722 0.00516414425769727 0.0496779828553007 FOS/JUNB/CEBPB/FBN1 4 GO:0051702 biological process involved in interaction with symbiont 4/138 94/18722 0.00516414425769727 0.0496779828553007 FN1/GPX1/TREM1/JUN 4 GO:0071456 cellular response to hypoxia 5/138 151/18722 0.00524630676775575 0.0496779828553007 EGR1/PTGS2/BNIP3L/HIF1A/PLK3 5 GO:0090132 epithelium migration 8/138 360/18722 0.00527320001807293 0.0496779828553007 PTGS2/GPX1/HMGB1/MYH9/HIF1A/ANXA1/EGR3/RHOB 8 GO:0006089 lactate metabolic process 2/138 15/18722 0.00531852123605201 0.0496779828553007 LDHA/HIF1A 2 GO:0045064 T-helper 2 cell differentiation 2/138 15/18722 0.00531852123605201 0.0496779828553007 ANXA1/BCL3 2 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 2/138 15/18722 0.00531852123605201 0.0496779828553007 BTG2/ZFP36 2 GO:0071871 response to epinephrine 2/138 15/18722 0.00531852123605201 0.0496779828553007 SNCA/PDE4B 2 GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response 2/138 15/18722 0.00531852123605201 0.0496779828553007 PPP1R15A/PPP1R15B 2 GO:0002673 regulation of acute inflammatory response 3/138 48/18722 0.00531945342827151 0.0496779828553007 PTGS2/OSM/IL1B 3 GO:0045912 negative regulation of carbohydrate metabolic process 3/138 48/18722 0.00531945342827151 0.0496779828553007 PLEK/DDIT4/MIDN 3 GO:0032479 regulation of type I interferon production 4/138 95/18722 0.00536085144479645 0.0497308319028951 HMGB1/RIOK3/REL/HMGB2 4 GO:0032606 type I interferon production 4/138 95/18722 0.00536085144479645 0.0497308319028951 HMGB1/RIOK3/REL/HMGB2 4 GO:0051098 regulation of binding 8/138 363/18722 0.00553681000505022 0.0511482082140679 NFKBIA/PLAUR/HMGB1/C4orf3/JUN/BCL3/TAF10/HMGB2 8 GO:0046651 lymphocyte proliferation 7/138 288/18722 0.00555039844795132 0.0511482082140679 CEBPB/HMGB1/IL1B/ANXA1/CD55/IRS2/MIF 7 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 3/138 49/18722 0.00563618198927574 0.0517673085021597 GPX1/SKIL/HMGB2 3 GO:0008360 regulation of cell shape 5/138 154/18722 0.00569598968334365 0.0517988230578943 FN1/MYH9/ANXA1/FGD3/RHOB 5 GO:0090130 tissue migration 8/138 365/18722 0.00571807019524531 0.0517988230578943 PTGS2/GPX1/HMGB1/MYH9/HIF1A/ANXA1/EGR3/RHOB 8 GO:0044403 biological process involved in symbiotic interaction 7/138 290/18722 0.00575908912521348 0.0517988230578943 CXCL8/FN1/GPX1/TREM1/JUN/CXCR4/CD55 7 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 4/138 97/18722 0.00576917967148546 0.0517988230578943 GPX1/MCL1/IL1B/HMGB2 4 GO:0006606 protein import into nucleus 5/138 155/18722 0.00585174653009548 0.0517988230578943 PTGS2/NFKBIA/PPP1R10/FAM53C/BCL3 5 GO:0007519 skeletal muscle tissue development 5/138 155/18722 0.00585174653009548 0.0517988230578943 FOS/EGR1/BTG2/GPX1/DDX5 5 GO:0034614 cellular response to reactive oxygen species 5/138 155/18722 0.00585174653009548 0.0517988230578943 FOS/KLF2/JUN/ANXA1/RHOB 5 GO:0032943 mononuclear cell proliferation 7/138 291/18722 0.00586561414604 0.0517988230578943 CEBPB/HMGB1/IL1B/ANXA1/CD55/IRS2/MIF 7 GO:0009615 response to virus 8/138 367/18722 0.00590382882508583 0.0517988230578943 IVNS1ABP/BNIP3L/DDIT4/RIOK3/CXCR4/DDX21/HIF1A/BCL3 8 GO:0050873 brown fat cell differentiation 3/138 50/18722 0.00596400107170439 0.0517988230578943 PTGS2/CEBPB/LRG1 3 GO:0002367 cytokine production involved in immune response 4/138 98/18722 0.00598090900457426 0.0517988230578943 TREM1/DDX21/IL1B/CD55 4 GO:0032642 regulation of chemokine production 4/138 98/18722 0.00598090900457426 0.0517988230578943 EGR1/HMGB1/HIF1A/IL1B 4 GO:0071692 protein localization to extracellular region 8/138 368/18722 0.005998417165812 0.0517988230578943 PLEK/SERP1/MIDN/FBN1/HIF1A/IL1B/ANXA1/IRS2 8 GO:0046631 alpha-beta T cell activation 5/138 156/18722 0.00601048410570536 0.0517988230578943 NFKBIZ/HMGB1/ANXA1/CD55/BCL3 5 GO:0022407 regulation of cell-cell adhesion 9/138 448/18722 0.00602337271183908 0.0517988230578943 PLAUR/CEBPB/NFKBIZ/HMGB1/IL1B/ANXA1/EGR3/CD55/MAP3K8 9 GO:0010225 response to UV-C 2/138 16/18722 0.00604909000855754 0.0517988230578943 BCL3/HMGN1 2 GO:0010919 regulation of inositol phosphate biosynthetic process 2/138 16/18722 0.00604909000855754 0.0517988230578943 PLEK/SNCA 2 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway 2/138 16/18722 0.00604909000855754 0.0517988230578943 HIF1A/IL1B 2 GO:0061684 chaperone-mediated autophagy 2/138 16/18722 0.00604909000855754 0.0517988230578943 SNCA/PLK3 2 GO:0070365 hepatocyte differentiation 2/138 16/18722 0.00604909000855754 0.0517988230578943 ANXA1/TAF10 2 GO:0071639 positive regulation of monocyte chemotactic protein-1 production 2/138 16/18722 0.00604909000855754 0.0517988230578943 HMGB1/IL1B 2 GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 2/138 16/18722 0.00604909000855754 0.0517988230578943 PLAUR/FAS 2 GO:0002274 myeloid leukocyte activation 6/138 223/18722 0.00623764114612293 0.0532495561646016 CXCL8/JUND/SNCA/HMGB1/JMJD6/MIF 6 GO:0007159 leukocyte cell-cell adhesion 8/138 371/18722 0.00628912474139755 0.0533467535308429 CEBPB/NFKBIZ/HMGB1/IL1B/ANXA1/EGR3/CD55/MAP3K8 8 GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 3/138 51/18722 0.00630301036876794 0.0533467535308429 NFKBIZ/HMGB1/ANXA1 3 GO:0046879 hormone secretion 7/138 295/18722 0.00630653320576619 0.0533467535308429 OSM/SERP1/MIDN/HIF1A/IL1B/ANXA1/IRS2 7 GO:0032984 protein-containing complex disassembly 6/138 224/18722 0.00637141550663465 0.0537322707726189 PLEK/DDIT4/ETF1/GSPT1/CHMP5/MID1IP1 6 GO:0050890 cognition 7/138 296/18722 0.00642052945982928 0.0539828806244861 FOS/PTGS2/BTG2/CEBPB/JUN/HIF1A/SGK1 7 GO:0051170 import into nucleus 5/138 159/18722 0.00650487576878983 0.0545273170618737 PTGS2/NFKBIA/PPP1R10/FAM53C/BCL3 5 GO:0042102 positive regulation of T cell proliferation 4/138 101/18722 0.00664699511000424 0.0554375727794946 HMGB1/IL1B/ANXA1/CD55 4 GO:0043277 apoptotic cell clearance 3/138 52/18722 0.00665330553659763 0.0554375727794946 HMGB1/ANXA1/JMJD6 3 GO:0033151 V(D)J recombination 2/138 17/18722 0.00682269774114546 0.0561455693035462 HMGB1/HMGB2 2 GO:0060644 mammary gland epithelial cell differentiation 2/138 17/18722 0.00682269774114546 0.0561455693035462 CEBPB/HIF1A 2 GO:0070293 renal absorption 2/138 17/18722 0.00682269774114546 0.0561455693035462 HBB/SGK1 2 GO:0070875 positive regulation of glycogen metabolic process 2/138 17/18722 0.00682269774114546 0.0561455693035462 HMGB1/IRS2 2 GO:0036294 cellular response to decreased oxygen levels 5/138 161/18722 0.00684991183085287 0.0561455693035462 EGR1/PTGS2/BNIP3L/HIF1A/PLK3 5 GO:0032677 regulation of interleukin-8 production 4/138 102/18722 0.00687949663403135 0.0561455693035462 HMGB1/IL1B/ANXA1/BCL3 4 GO:1902106 negative regulation of leukocyte differentiation 4/138 102/18722 0.00687949663403135 0.0561455693035462 TRIB1/HMGB1/FBN1/ANXA1 4 GO:0006913 nucleocytoplasmic transport 7/138 301/18722 0.00701372791269654 0.0569073025686136 PTGS2/NFKBIA/PPP1R10/IL1B/HNRNPA2B1/FAM53C/BCL3 7 GO:0051169 nuclear transport 7/138 301/18722 0.00701372791269654 0.0569073025686136 PTGS2/NFKBIA/PPP1R10/IL1B/HNRNPA2B1/FAM53C/BCL3 7 GO:0001649 osteoblast differentiation 6/138 229/18722 0.0070718186012576 0.0570821350039121 JUNB/CEBPB/JUND/DDX5/DDX21/HEMGN 6 GO:0050878 regulation of body fluid levels 8/138 379/18722 0.00711682545953985 0.0570821350039121 FN1/PLAUR/PLEK/TLN1/ACTG1/HBB/MYH9/HIF1A 8 GO:0030593 neutrophil chemotaxis 4/138 103/18722 0.00711731974357078 0.0570821350039121 CXCL8/TREM1/CXCL1/PDE4B 4 GO:0032637 interleukin-8 production 4/138 103/18722 0.00711731974357078 0.0570821350039121 HMGB1/IL1B/ANXA1/BCL3 4 GO:0006633 fatty acid biosynthetic process 5/138 163/18722 0.00720757186591666 0.0576398635139254 PTGS2/IL1B/ANXA1/MID1IP1/MIF 5 GO:0050678 regulation of epithelial cell proliferation 8/138 381/18722 0.00733606573285231 0.0584993436519426 ZFP36/GPX1/HMGB1/HIF1A/EGR3/LRG1/HMGN1/HMGB2 8 GO:0046634 regulation of alpha-beta T cell activation 4/138 104/18722 0.0073605145974959 0.0585266060709459 NFKBIZ/HMGB1/ANXA1/CD55 4 GO:0001706 endoderm formation 3/138 54/18722 0.00738811632610827 0.05857871149732 DUSP1/FN1/DUSP2 3 GO:0006402 mRNA catabolic process 6/138 232/18722 0.00751793929310874 0.0589499231410486 BTG2/ZFP36/DDX5/YBX1/ETF1/GSPT1 6 GO:0032635 interleukin-6 production 5/138 165/18722 0.00757808549539598 0.0589499231410486 CEBPB/KLF2/HMGB1/IL1B/AKIRIN2 5 GO:0032675 regulation of interleukin-6 production 5/138 165/18722 0.00757808549539598 0.0589499231410486 CEBPB/KLF2/HMGB1/IL1B/AKIRIN2 5 GO:0050796 regulation of insulin secretion 5/138 165/18722 0.00757808549539598 0.0589499231410486 SERP1/MIDN/HIF1A/IL1B/IRS2 5 GO:0006415 translational termination 2/138 18/18722 0.00763867967702233 0.0589499231410486 ETF1/GSPT1 2 GO:0006595 polyamine metabolic process 2/138 18/18722 0.00763867967702233 0.0589499231410486 SAT1/AOC1 2 GO:0030730 sequestering of triglyceride 2/138 18/18722 0.00763867967702233 0.0589499231410486 IL1B/PLIN2 2 GO:0031649 heat generation 2/138 18/18722 0.00763867967702233 0.0589499231410486 PTGS2/IL1B 2 GO:0036499 PERK-mediated unfolded protein response 2/138 18/18722 0.00763867967702233 0.0589499231410486 PPP1R15A/PPP1R15B 2 GO:0009914 hormone transport 7/138 306/18722 0.00764675610992402 0.0589499231410486 OSM/SERP1/MIDN/HIF1A/IL1B/ANXA1/IRS2 7 GO:0060538 skeletal muscle organ development 5/138 166/18722 0.00776823355086326 0.0592649661051848 FOS/EGR1/BTG2/GPX1/DDX5 5 GO:0010676 positive regulation of cellular carbohydrate metabolic process 3/138 55/18722 0.0077728036753117 0.0592649661051848 SNCA/HMGB1/IRS2 3 GO:0038066 p38MAPK cascade 3/138 55/18722 0.0077728036753117 0.0592649661051848 DUSP1/ZFP36/IL1B 3 GO:0043331 response to dsRNA 3/138 55/18722 0.0077728036753117 0.0592649661051848 NFKBIA/RIOK3/DDX21 3 GO:0071887 leukocyte apoptotic process 4/138 106/18722 0.00786321697025354 0.0596276098861461 HIF1A/ANXA1/IRS2/FAS 4 GO:1903707 negative regulation of hemopoiesis 4/138 106/18722 0.00786321697025354 0.0596276098861461 TRIB1/HMGB1/FBN1/ANXA1 4 GO:2000116 regulation of cysteine-type endopeptidase activity 6/138 235/18722 0.00798406560756997 0.0603794961572479 PTGS2/PLAUR/GPX1/SNCA/HMGB1/FAS 6 GO:0007229 integrin-mediated signaling pathway 4/138 107/18722 0.0081228215851874 0.0604645273863978 FN1/PLEK/TLN1/MYH9 4 GO:0008637 apoptotic mitochondrial changes 4/138 107/18722 0.0081228215851874 0.0604645273863978 PLAUR/BNIP3L/GPX1/JUN 4 GO:0051051 negative regulation of transport 9/138 470/18722 0.00813429646189733 0.0604645273863978 PTGS2/OSM/SNCA/MIDN/HMGB1/C4orf3/IL1B/ANXA1/IRS2 9 GO:0030072 peptide hormone secretion 6/138 236/18722 0.00814397062798488 0.0604645273863978 SERP1/MIDN/HIF1A/IL1B/ANXA1/IRS2 6 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 5/138 168/18722 0.00815845314231977 0.0604645273863978 NFKBIZ/HMGB1/IL1B/ANXA1/CD55 5 GO:0043388 positive regulation of DNA binding 3/138 56/18722 0.00816912048051942 0.0604645273863978 PLAUR/HMGB1/HMGB2 3 GO:0043470 regulation of carbohydrate catabolic process 3/138 56/18722 0.00816912048051942 0.0604645273863978 DDIT4/HMGB1/HIF1A 3 GO:0071385 cellular response to glucocorticoid stimulus 3/138 56/18722 0.00816912048051942 0.0604645273863978 ZFP36/DDIT4/ANXA1 3 GO:0033673 negative regulation of kinase activity 6/138 237/18722 0.00830617027356859 0.0613158405075368 DUSP1/TRIB1/SNCA/MIDN/IL1B/IRS2 6 GO:0006631 fatty acid metabolic process 8/138 390/18722 0.00838642499699623 0.0615930925727158 PTGS2/GPX1/SNCA/IL1B/ANXA1/MID1IP1/IRS2/MIF 8 GO:0033138 positive regulation of peptidyl-serine phosphorylation 4/138 108/18722 0.00838799212542554 0.0615930925727158 PTGS2/OSM/SNCA/MIF 4 GO:0051403 stress-activated MAPK cascade 6/138 239/18722 0.00863752475251694 0.0632585036480385 DUSP1/TRIB1/ZFP36/HMGB1/IL1B/FAS 6 GO:0001667 ameboidal-type cell migration 9/138 475/18722 0.00868439333232626 0.0634348205875695 PTGS2/FN1/GPX1/HMGB1/MYH9/HIF1A/ANXA1/EGR3/RHOB 9 GO:0042129 regulation of T cell proliferation 5/138 171/18722 0.00876900959898303 0.0635524836301296 CEBPB/HMGB1/IL1B/ANXA1/CD55 5 GO:0046890 regulation of lipid biosynthetic process 5/138 171/18722 0.00876900959898303 0.0635524836301296 EGR1/PTGS2/IL1B/ANXA1/MID1IP1 5 GO:0051048 negative regulation of secretion 5/138 171/18722 0.00876900959898303 0.0635524836301296 OSM/SNCA/MIDN/IL1B/ANXA1 5 GO:0018105 peptidyl-serine phosphorylation 7/138 315/18722 0.00889151267627854 0.0642012743336315 PTGS2/OSM/DDIT4/SNCA/SGK1/MORC3/MIF 7 GO:0042770 signal transduction in response to DNA damage 5/138 172/18722 0.00897936607658363 0.0642012743336315 DDX5/PPP1R10/BCL3/PLK3/MIF 5 GO:0002763 positive regulation of myeloid leukocyte differentiation 3/138 58/18722 0.00899694466048016 0.0642012743336315 FOS/TRIB1/JUN 3 GO:0010574 regulation of vascular endothelial growth factor production 3/138 58/18722 0.00899694466048016 0.0642012743336315 PTGS2/HIF1A/IL1B 3 GO:0032481 positive regulation of type I interferon production 3/138 58/18722 0.00899694466048016 0.0642012743336315 HMGB1/RIOK3/HMGB2 3 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 3/138 58/18722 0.00899694466048016 0.0642012743336315 MCL1/UBB/SKIL 3 GO:0002790 peptide secretion 6/138 242/18722 0.00915221068483508 0.0651422054626497 SERP1/MIDN/HIF1A/IL1B/ANXA1/IRS2 6 GO:0070661 leukocyte proliferation 7/138 318/18722 0.00933777723031694 0.0651555245227491 CEBPB/HMGB1/IL1B/ANXA1/CD55/IRS2/MIF 7 GO:0003159 morphogenesis of an endothelium 2/138 20/18722 0.00939514374783002 0.0651555245227491 CXCR4/RHOB 2 GO:0032495 response to muramyl dipeptide 2/138 20/18722 0.00939514374783002 0.0651555245227491 NFKBIA/CHMP5 2 GO:0043555 regulation of translation in response to stress 2/138 20/18722 0.00939514374783002 0.0651555245227491 PPP1R15A/PPP1R15B 2 GO:0045063 T-helper 1 cell differentiation 2/138 20/18722 0.00939514374783002 0.0651555245227491 HMGB1/ANXA1 2 GO:0061154 endothelial tube morphogenesis 2/138 20/18722 0.00939514374783002 0.0651555245227491 CXCR4/RHOB 2 GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 2/138 20/18722 0.00939514374783002 0.0651555245227491 GPX1/HIF1A 2 GO:0001836 release of cytochrome c from mitochondria 3/138 59/18722 0.00942859408216376 0.0651555245227491 PLAUR/GPX1/JUN 3 GO:0032768 regulation of monooxygenase activity 3/138 59/18722 0.00942859408216376 0.0651555245227491 SNCA/HIF1A/IL1B 3 GO:0035306 positive regulation of dephosphorylation 3/138 59/18722 0.00942859408216376 0.0651555245227491 PPP1R15A/PLEK/PPP1R15B 3 GO:0051353 positive regulation of oxidoreductase activity 3/138 59/18722 0.00942859408216376 0.0651555245227491 SNCA/HIF1A/IL1B 3 GO:0032609 interferon-gamma production 4/138 112/18722 0.00950526157248873 0.0651555245227491 HMGB1/IL1B/BCL3/PDE4B 4 GO:0032649 regulation of interferon-gamma production 4/138 112/18722 0.00950526157248873 0.0651555245227491 HMGB1/IL1B/BCL3/PDE4B 4 GO:0046632 alpha-beta T cell differentiation 4/138 112/18722 0.00950526157248873 0.0651555245227491 NFKBIZ/HMGB1/ANXA1/BCL3 4 GO:1901222 regulation of NIK/NF-kappaB signaling 4/138 112/18722 0.00950526157248873 0.0651555245227491 NFKBIA/HMGB1/IL1B/BCL3 4 GO:0009895 negative regulation of catabolic process 7/138 320/18722 0.00964428080308618 0.0657843957720314 ZFP36/GABARAPL2/DDIT4/SNCA/MCL1/YBX1/IL1B 7 GO:0071496 cellular response to external stimulus 7/138 320/18722 0.00964428080308618 0.0657843957720314 FOS/PTGS2/GABARAPL2/AOC1/JUN/IL1B/FAS 7 GO:0044344 cellular response to fibroblast growth factor stimulus 4/138 113/18722 0.00979895187897765 0.0666759977486425 CXCL8/ZFP36/SNCA/EGR3 4 GO:0010634 positive regulation of epithelial cell migration 5/138 176/18722 0.00985570533540121 0.0668472346097809 PTGS2/HMGB1/HIF1A/ANXA1/RHOB 5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 3/138 60/18722 0.00987215717736973 0.0668472346097809 DDX5/SRSF2/SAP18 3 GO:0031098 stress-activated protein kinase signaling cascade 6/138 247/18722 0.0100582728133433 0.0676716426110524 DUSP1/TRIB1/ZFP36/HMGB1/IL1B/FAS 6 GO:0002286 T cell activation involved in immune response 4/138 114/18722 0.0100984794343635 0.0676716426110524 NFKBIZ/HMGB1/ANXA1/BCL3 4 GO:1903008 organelle disassembly 4/138 114/18722 0.0100984794343635 0.0676716426110524 BNIP3L/GABARAPL2/HIF1A/PLK3 4 GO:0030865 cortical cytoskeleton organization 3/138 61/18722 0.0103276961925665 0.0676716426110524 PLEK/TLN1/RHOB 3 GO:0043030 regulation of macrophage activation 3/138 61/18722 0.0103276961925665 0.0676716426110524 JUND/SNCA/MIF 3 GO:0071384 cellular response to corticosteroid stimulus 3/138 61/18722 0.0103276961925665 0.0676716426110524 ZFP36/DDIT4/ANXA1 3 GO:0002689 negative regulation of leukocyte chemotaxis 2/138 21/18722 0.0103343327738761 0.0676716426110524 DUSP1/MIF 2 GO:0030449 regulation of complement activation 2/138 21/18722 0.0103343327738761 0.0676716426110524 IL1B/CD55 2 GO:0030502 negative regulation of bone mineralization 2/138 21/18722 0.0103343327738761 0.0676716426110524 SRGN/HIF1A 2 GO:0032516 positive regulation of phosphoprotein phosphatase activity 2/138 21/18722 0.0103343327738761 0.0676716426110524 PPP1R15A/PPP1R15B 2 GO:0046885 regulation of hormone biosynthetic process 2/138 21/18722 0.0103343327738761 0.0676716426110524 EGR1/HIF1A 2 GO:0071498 cellular response to fluid shear stress 2/138 21/18722 0.0103343327738761 0.0676716426110524 PTGS2/KLF2 2 GO:0071605 monocyte chemotactic protein-1 production 2/138 21/18722 0.0103343327738761 0.0676716426110524 HMGB1/IL1B 2 GO:0071637 regulation of monocyte chemotactic protein-1 production 2/138 21/18722 0.0103343327738761 0.0676716426110524 HMGB1/IL1B 2 GO:0001936 regulation of endothelial cell proliferation 5/138 179/18722 0.0105503664911663 0.0689241078519151 HMGB1/HIF1A/EGR3/LRG1/HMGB2 5 GO:0008286 insulin receptor signaling pathway 4/138 116/18722 0.0107152169413667 0.0698371165054412 PTPRE/SOCS3/IL1B/IRS2 4 GO:0007517 muscle organ development 7/138 327/18722 0.0107752432445409 0.0698679914696213 FOS/EGR1/BTG2/GPX1/SERP1/DDX5/EGR3 7 GO:0002260 lymphocyte homeostasis 3/138 62/18722 0.0107952699719501 0.0698679914696213 HIF1A/SKIL/FAS 3 GO:0010573 vascular endothelial growth factor production 3/138 62/18722 0.0107952699719501 0.0698679914696213 PTGS2/HIF1A/IL1B 3 GO:0034612 response to tumor necrosis factor 6/138 253/18722 0.0112278426238303 0.0722131668446791 PTGS2/CXCL8/NFKBIA/ZFP36/KLF2/FAS 6 GO:0032069 regulation of nuclease activity 2/138 22/18722 0.0113133096458067 0.0722131668446791 HMGB1/HMGB2 2 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation 2/138 22/18722 0.0113133096458067 0.0722131668446791 HMGB1/ANXA1 2 GO:0045624 positive regulation of T-helper cell differentiation 2/138 22/18722 0.0113133096458067 0.0722131668446791 NFKBIZ/ANXA1 2 GO:0051412 response to corticosterone 2/138 22/18722 0.0113133096458067 0.0722131668446791 FOS/FOSB 2 GO:0140467 integrated stress response signaling 2/138 22/18722 0.0113133096458067 0.0722131668446791 PPP1R15A/PPP1R15B 2 GO:0019216 regulation of lipid metabolic process 7/138 331/18722 0.011463311811463 0.0730031962730013 EGR1/PTGS2/SNCA/IL1B/ANXA1/MID1IP1/IRS2 7 GO:0045670 regulation of osteoclast differentiation 3/138 64/18722 0.0117667405424469 0.0744246339309767 FOS/CEBPB/FBN1 3 GO:0046888 negative regulation of hormone secretion 3/138 64/18722 0.0117667405424469 0.0744246339309767 OSM/MIDN/IL1B 3 GO:1900076 regulation of cellular response to insulin stimulus 3/138 64/18722 0.0117667405424469 0.0744246339309767 PTPRE/SOCS3/IL1B 3 GO:0034976 response to endoplasmic reticulum stress 6/138 256/18722 0.011847373446305 0.0747647172359793 CXCL8/CEBPB/PPP1R15A/SERP1/JUN/PPP1R15B 6 GO:0002720 positive regulation of cytokine production involved in immune response 3/138 65/18722 0.0122707385385433 0.0766231546651282 DDX21/IL1B/CD55 3 GO:0015909 long-chain fatty acid transport 3/138 65/18722 0.0122707385385433 0.0766231546651282 ANXA1/PLIN2/IRS2 3 GO:0001919 regulation of receptor recycling 2/138 23/18722 0.0123314455926145 0.0766231546651282 SNCA/CHMP5 2 GO:0031338 regulation of vesicle fusion 2/138 23/18722 0.0123314455926145 0.0766231546651282 SNCA/ANXA1 2 GO:0035994 response to muscle stretch 2/138 23/18722 0.0123314455926145 0.0766231546651282 FOS/NFKBIA 2 GO:0060353 regulation of cell adhesion molecule production 2/138 23/18722 0.0123314455926145 0.0766231546651282 CXCL8/IL1B 2 GO:0001704 formation of primary germ layer 4/138 121/18722 0.0123621259233355 0.0766231546651282 DUSP1/FN1/DUSP2/ETS2 4 GO:0043244 regulation of protein-containing complex disassembly 4/138 121/18722 0.0123621259233355 0.0766231546651282 PLEK/ETF1/GSPT1/MID1IP1 4 GO:0061136 regulation of proteasomal protein catabolic process 5/138 187/18722 0.0125652569428292 0.0777091334930971 TRIB1/GABARAPL2/GPX1/UBB/PLK3 5 GO:0002688 regulation of leukocyte chemotaxis 4/138 122/18722 0.0127098350647867 0.0782113146151659 DUSP1/CXCL8/HMGB1/MIF 4 GO:1990266 neutrophil migration 4/138 122/18722 0.0127098350647867 0.0782113146151659 CXCL8/TREM1/CXCL1/PDE4B 4 GO:0018209 peptidyl-serine modification 7/138 338/18722 0.0127433652682135 0.0782113146151659 PTGS2/OSM/DDIT4/SNCA/SGK1/MORC3/MIF 7 GO:0045600 positive regulation of fat cell differentiation 3/138 66/18722 0.0127869738231766 0.0782113146151659 PTGS2/ZFP36/CEBPB 3 GO:0046626 regulation of insulin receptor signaling pathway 3/138 66/18722 0.0127869738231766 0.0782113146151659 PTPRE/SOCS3/IL1B 3 GO:0006879 cellular iron ion homeostasis 3/138 67/18722 0.0133154891003007 0.0807342182268776 HIF1A/FTH1/ALAS2 3 GO:0032890 regulation of organic acid transport 3/138 67/18722 0.0133154891003007 0.0807342182268776 SNCA/IL1B/IRS2 3 GO:0046635 positive regulation of alpha-beta T cell activation 3/138 67/18722 0.0133154891003007 0.0807342182268776 NFKBIZ/ANXA1/CD55 3 GO:0061180 mammary gland epithelium development 3/138 67/18722 0.0133154891003007 0.0807342182268776 CEBPB/GPX1/HIF1A 3 GO:0002726 positive regulation of T cell cytokine production 2/138 24/18722 0.013388118833171 0.0809981189406845 IL1B/CD55 2 GO:0010508 positive regulation of autophagy 4/138 124/18722 0.0134238827322292 0.0810383202685331 BNIP3L/HMGB1/HIF1A/PLK3 4 GO:0015833 peptide transport 6/138 264/18722 0.0136168802106217 0.0820254926973163 SERP1/MIDN/HIF1A/IL1B/ANXA1/IRS2 6 GO:0046637 regulation of alpha-beta T cell differentiation 3/138 68/18722 0.0138563240148146 0.083287580417341 NFKBIZ/HMGB1/ANXA1 3 GO:0001935 endothelial cell proliferation 5/138 193/18722 0.0142374251445229 0.085210224037005 HMGB1/HIF1A/EGR3/LRG1/HMGB2 5 GO:0007565 female pregnancy 5/138 193/18722 0.0142374251445229 0.085210224037005 FOS/JUNB/PTGS2/FOSB/IL1B 5 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 2/138 25/18722 0.0144827145085723 0.0860358845781758 TRIB1/CD55 2 GO:0060706 cell differentiation involved in embryonic placenta development 2/138 25/18722 0.0144827145085723 0.0860358845781758 SOCS3/KRT19 2 GO:1901798 positive regulation of signal transduction by p53 class mediator 2/138 25/18722 0.0144827145085723 0.0860358845781758 DDX5/UBB 2 GO:0050777 negative regulation of immune response 5/138 194/18722 0.0145299553545608 0.0860358845781758 GPX1/SAMSN1/RIOK3/ANXA1/CD55 5 GO:1901654 response to ketone 5/138 194/18722 0.0145299553545608 0.0860358845781758 FOS/DUSP1/KLF2/DDIT4/FOSB 5 GO:0050708 regulation of protein secretion 6/138 268/18722 0.0145676460951593 0.0860759216195933 SERP1/MIDN/HIF1A/IL1B/ANXA1/IRS2 6 GO:0032612 interleukin-1 production 4/138 128/18722 0.0149274929688504 0.0878292028167244 EGR1/HMGB1/ANXA1/IL1R2 4 GO:0032652 regulation of interleukin-1 production 4/138 128/18722 0.0149274929688504 0.0878292028167244 EGR1/HMGB1/ANXA1/IL1R2 4 GO:0002548 monocyte chemotaxis 3/138 70/18722 0.0149750963673768 0.0879234033552947 DUSP1/HMGB1/ANXA1 3 GO:0031032 actomyosin structure organization 5/138 196/18722 0.0151270816347635 0.0884425802301401 ACTG1/MYH9/GPR65/PHACTR1/KRT19 5 GO:0090276 regulation of peptide hormone secretion 5/138 196/18722 0.0151270816347635 0.0884425802301401 SERP1/MIDN/HIF1A/IL1B/IRS2 5 GO:0010952 positive regulation of peptidase activity 5/138 197/18722 0.0154317225143319 0.089414609678599 FN1/SNCA/HMGB1/FAS/AKIRIN2 5 GO:0042594 response to starvation 5/138 197/18722 0.0154317225143319 0.089414609678599 ZFP36/GABARAPL2/AOC1/JUN/FAS 5 GO:0001963 synaptic transmission, dopaminergic 2/138 26/18722 0.0156146246150913 0.089414609678599 PTGS2/SNCA 2 GO:0002407 dendritic cell chemotaxis 2/138 26/18722 0.0156146246150913 0.089414609678599 HMGB1/CXCR4 2 GO:0033598 mammary gland epithelial cell proliferation 2/138 26/18722 0.0156146246150913 0.089414609678599 CEBPB/GPX1 2 GO:0034643 establishment of mitochondrion localization, microtubule-mediated 2/138 26/18722 0.0156146246150913 0.089414609678599 HIF1A/UBB 2 GO:0046639 negative regulation of alpha-beta T cell differentiation 2/138 26/18722 0.0156146246150913 0.089414609678599 HMGB1/ANXA1 2 GO:0046697 decidualization 2/138 26/18722 0.0156146246150913 0.089414609678599 JUNB/PTGS2 2 GO:0047497 mitochondrion transport along microtubule 2/138 26/18722 0.0156146246150913 0.089414609678599 HIF1A/UBB 2 GO:0060352 cell adhesion molecule production 2/138 26/18722 0.0156146246150913 0.089414609678599 CXCL8/IL1B 2 GO:0007179 transforming growth factor beta receptor signaling pathway 5/138 198/18722 0.0157404446993733 0.0899500156023737 FOS/FBN1/JUN/LRG1/SKIL 5 GO:0042098 T cell proliferation 5/138 199/18722 0.0160532700008517 0.0913160500730062 CEBPB/HMGB1/IL1B/ANXA1/CD55 5 GO:0045089 positive regulation of innate immune response 4/138 131/18722 0.0161223418636451 0.0913160500730062 HMGB1/RIOK3/HMGB2/AKIRIN2 4 GO:0032729 positive regulation of interferon-gamma production 3/138 72/18722 0.016143548916967 0.0913160500730062 IL1B/BCL3/PDE4B 3 GO:0050709 negative regulation of protein secretion 3/138 72/18722 0.016143548916967 0.0913160500730062 MIDN/IL1B/ANXA1 3 GO:0070227 lymphocyte apoptotic process 3/138 72/18722 0.016143548916967 0.0913160500730062 HIF1A/IRS2/FAS 3 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 7/138 355/18722 0.0162768004040887 0.0918830335184158 FOS/EGR1/DDX5/FBN1/JUN/LRG1/SKIL 7 GO:0002791 regulation of peptide secretion 5/138 200/18722 0.0163702199886127 0.092223324348804 SERP1/MIDN/HIF1A/IL1B/IRS2 5 GO:0045667 regulation of osteoblast differentiation 4/138 132/18722 0.0165335844975612 0.0929554861751776 CEBPB/JUND/DDX5/HEMGN 4 GO:0002825 regulation of T-helper 1 type immune response 2/138 27/18722 0.0167832479377311 0.0939794346291863 IL1B/ANXA1 2 GO:1903203 regulation of oxidative stress-induced neuron death 2/138 27/18722 0.0167832479377311 0.0939794346291863 MCL1/HIF1A 2 GO:0090087 regulation of peptide transport 5/138 202/18722 0.0170165790852127 0.0950946578195723 SERP1/MIDN/HIF1A/IL1B/IRS2 5 GO:0006401 RNA catabolic process 6/138 278/18722 0.0171452183465943 0.0955448734083541 BTG2/ZFP36/DDX5/YBX1/ETF1/GSPT1 6 GO:0009306 protein secretion 7/138 359/18722 0.0172001371101636 0.0955448734083541 PLEK/SERP1/MIDN/HIF1A/IL1B/ANXA1/IRS2 7 GO:1901653 cellular response to peptide 7/138 359/18722 0.0172001371101636 0.0955448734083541 PTPRE/KLF2/FBN1/SOCS3/IL1B/CHMP5/IRS2 7 GO:0002437 inflammatory response to antigenic stimulus 3/138 74/18722 0.0173618941773177 0.0955662989235041 GPX1/HMGB1/HMGB2 3 GO:0030968 endoplasmic reticulum unfolded protein response 3/138 74/18722 0.0173618941773177 0.0955662989235041 PPP1R15A/SERP1/PPP1R15B 3 GO:1903201 regulation of oxidative stress-induced cell death 3/138 74/18722 0.0173618941773177 0.0955662989235041 GPX1/MCL1/HIF1A 3 GO:0008277 regulation of G protein-coupled receptor signaling pathway 4/138 134/18722 0.0173756907133644 0.0955662989235041 CXCL8/PLEK/SNCA/PDE4B 4 GO:0061041 regulation of wound healing 4/138 134/18722 0.0173756907133644 0.0955662989235041 HMGB1/ACTG1/CXCR4/ANXA1 4 GO:0035592 establishment of protein localization to extracellular region 7/138 360/18722 0.0174366486105734 0.09571241239295 PLEK/SERP1/MIDN/HIF1A/IL1B/ANXA1/IRS2 7 GO:0007249 I-kappaB kinase/NF-kappaB signaling 6/138 281/18722 0.0179760711179389 0.0974040846601364 NFKBIA/RIOK3/DDX21/IL1B/BCL3/REL 6 GO:0032958 inositol phosphate biosynthetic process 2/138 28/18722 0.0179879899843736 0.0974040846601364 PLEK/SNCA 2 GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT 2/138 28/18722 0.0179879899843736 0.0974040846601364 SOCS3/BCL3 2 GO:0050996 positive regulation of lipid catabolic process 2/138 28/18722 0.0179879899843736 0.0974040846601364 IL1B/IRS2 2 GO:0071280 cellular response to copper ion 2/138 28/18722 0.0179879899843736 0.0974040846601364 SNCA/AOC1 2 GO:0090344 negative regulation of cell aging 2/138 28/18722 0.0179879899843736 0.0974040846601364 YBX1/MIF 2 GO:0033077 T cell differentiation in thymus 3/138 75/18722 0.0179898309433382 0.0974040846601364 IL1B/EGR3/JMJD6 3 GO:0003158 endothelium development 4/138 136/18722 0.0182441502138115 0.0983981977617005 GPX1/CXCR4/IL1B/RHOB 4 GO:0043624 cellular protein complex disassembly 4/138 136/18722 0.0182441502138115 0.0983981977617005 PLEK/ETF1/GSPT1/MID1IP1 4 GO:0017038 protein import 5/138 206/18722 0.0183597153801644 0.0988299572591829 PTGS2/NFKBIA/PPP1R10/FAM53C/BCL3 5 GO:0044262 cellular carbohydrate metabolic process 6/138 283/18722 0.0185451063410809 0.0996351948788188 PLEK/DDIT4/SNCA/MIDN/HMGB1/IRS2 6 GO:0030879 mammary gland development 4/138 137/18722 0.0186883317597162 0.10011372322617 CEBPB/GPX1/HIF1A/IRS2 4 GO:0050679 positive regulation of epithelial cell proliferation 5/138 207/18722 0.0187061214795575 0.10011372322617 HMGB1/HIF1A/EGR3/LRG1/HMGB2 5 GO:1901215 negative regulation of neuron death 5/138 208/18722 0.0190568159217531 0.101794853570516 BTG2/CEBPB/SNCA/HIF1A/REL 5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 2/138 29/18722 0.0192282629205199 0.101832020000327 BTG2/ZFP36 2 GO:0051654 establishment of mitochondrion localization 2/138 29/18722 0.0192282629205199 0.101832020000327 HIF1A/UBB 2 GO:0090025 regulation of monocyte chemotaxis 2/138 29/18722 0.0192282629205199 0.101832020000327 DUSP1/HMGB1 2 GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 2/138 29/18722 0.0192282629205199 0.101832020000327 UBB/MIF 2 GO:0000380 alternative mRNA splicing, via spliceosome 3/138 77/18722 0.0192833181962531 0.101832020000327 DDX5/SRSF2/SAP18 3 GO:0007492 endoderm development 3/138 77/18722 0.0192833181962531 0.101832020000327 DUSP1/FN1/DUSP2 3 GO:0002685 regulation of leukocyte migration 5/138 210/18722 0.0197711468503943 0.104013424734683 DUSP1/CXCL8/HMGB1/ANXA1/MIF 5 GO:0007623 circadian rhythm 5/138 210/18722 0.0197711468503943 0.104013424734683 EGR1/NFIL3/JUND/JUN/EGR3 5 GO:0008306 associative learning 3/138 78/18722 0.0199488951142416 0.104553248781421 FOS/BTG2/HIF1A 3 GO:0032024 positive regulation of insulin secretion 3/138 78/18722 0.0199488951142416 0.104553248781421 SERP1/HIF1A/IRS2 3 GO:0048147 negative regulation of fibroblast proliferation 2/138 30/18722 0.0205034855046153 0.106012227941965 FTH1/MORC3 2 GO:0060674 placenta blood vessel development 2/138 30/18722 0.0205034855046153 0.106012227941965 JUNB/SOCS3 2 GO:0070168 negative regulation of biomineral tissue development 2/138 30/18722 0.0205034855046153 0.106012227941965 SRGN/HIF1A 2 GO:0070229 negative regulation of lymphocyte apoptotic process 2/138 30/18722 0.0205034855046153 0.106012227941965 HIF1A/IRS2 2 GO:1900101 regulation of endoplasmic reticulum unfolded protein response 2/138 30/18722 0.0205034855046153 0.106012227941965 PPP1R15A/PPP1R15B 2 GO:1903579 negative regulation of ATP metabolic process 2/138 30/18722 0.0205034855046153 0.106012227941965 DDIT4/SNCA 2 GO:2000637 positive regulation of gene silencing by miRNA 2/138 30/18722 0.0205034855046153 0.106012227941965 ZFP36/DDX5 2 GO:0032355 response to estradiol 4/138 141/18722 0.0205320125263093 0.106012227941965 PTGS2/DUSP1/ANXA1/FAM210B 4 GO:0006446 regulation of translational initiation 3/138 79/18722 0.0206270409884991 0.106144215025548 PPP1R15A/EIF1/PPP1R15B 3 GO:0034504 protein localization to nucleus 6/138 290/18722 0.0206338556697167 0.106144215025548 PTGS2/NFKBIA/PPP1R10/FAM53C/BCL3/MORC3 6 GO:0052547 regulation of peptidase activity 8/138 461/18722 0.0210266654909513 0.107965332216453 PTGS2/FN1/PLAUR/GPX1/SNCA/HMGB1/FAS/AKIRIN2 8 GO:0072330 monocarboxylic acid biosynthetic process 5/138 214/18722 0.0212521014510797 0.108921912225331 PTGS2/IL1B/ANXA1/MID1IP1/MIF 5 GO:0023061 signal release 8/138 463/18722 0.0215120437260112 0.110051503105679 OSM/SERP1/SNCA/MIDN/HIF1A/IL1B/ANXA1/IRS2 8 GO:0036475 neuron death in response to oxidative stress 2/138 31/18722 0.0218130830239566 0.110422746745518 MCL1/HIF1A 2 GO:0060055 angiogenesis involved in wound healing 2/138 31/18722 0.0218130830239566 0.110422746745518 GPX1/CXCR4 2 GO:0060148 positive regulation of posttranscriptional gene silencing 2/138 31/18722 0.0218130830239566 0.110422746745518 ZFP36/DDX5 2 GO:0110150 negative regulation of biomineralization 2/138 31/18722 0.0218130830239566 0.110422746745518 SRGN/HIF1A 2 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 2/138 31/18722 0.0218130830239566 0.110422746745518 GPX1/HMGB2 2 GO:0010821 regulation of mitochondrion organization 4/138 144/18722 0.0219857564960327 0.110422746745518 PLAUR/BNIP3L/GPX1/HIF1A 4 GO:0000422 autophagy of mitochondrion 3/138 81/18722 0.0220210651971838 0.110422746745518 BNIP3L/GABARAPL2/HIF1A 3 GO:0006096 glycolytic process 3/138 81/18722 0.0220210651971838 0.110422746745518 DDIT4/LDHA/HIF1A 3 GO:0061726 mitochondrion disassembly 3/138 81/18722 0.0220210651971838 0.110422746745518 BNIP3L/GABARAPL2/HIF1A 3 GO:0071260 cellular response to mechanical stimulus 3/138 81/18722 0.0220210651971838 0.110422746745518 PTGS2/IL1B/FAS 3 GO:2000106 regulation of leukocyte apoptotic process 3/138 81/18722 0.0220210651971838 0.110422746745518 HIF1A/ANXA1/IRS2 3 GO:0043524 negative regulation of neuron apoptotic process 4/138 145/18722 0.0224839796471564 0.112541214672727 BTG2/CEBPB/SNCA/HIF1A 4 GO:0006757 ATP generation from ADP 3/138 82/18722 0.0227369503672534 0.113399521276104 DDIT4/LDHA/HIF1A 3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 3/138 82/18722 0.0227369503672534 0.113399521276104 GPX1/SKIL/HMGB2 3 GO:0045580 regulation of T cell differentiation 4/138 146/18722 0.0229890589207642 0.113924464267831 NFKBIZ/HMGB1/ANXA1/EGR3 4 GO:0010039 response to iron ion 2/138 32/18722 0.0231564872311734 0.113924464267831 SNCA/HIF1A 2 GO:0035767 endothelial cell chemotaxis 2/138 32/18722 0.0231564872311734 0.113924464267831 HMGB1/EGR3 2 GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 2/138 32/18722 0.0231564872311734 0.113924464267831 NFKBIZ/ANXA1 2 GO:2000191 regulation of fatty acid transport 2/138 32/18722 0.0231564872311734 0.113924464267831 IL1B/IRS2 2 GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 2/138 32/18722 0.0231564872311734 0.113924464267831 HMGB1/ANXA1 2 GO:0009746 response to hexose 5/138 219/18722 0.0232028240395111 0.113924464267831 EGR1/PTGS2/LDHA/HIF1A/IRS2 5 GO:0010720 positive regulation of cell development 6/138 298/18722 0.02321062567009 0.113924464267831 TRIB1/FN1/CXCR4/HIF1A/IL1B/SKIL 6 GO:0048511 rhythmic process 6/138 298/18722 0.02321062567009 0.113924464267831 EGR1/NFIL3/JUND/DDX5/JUN/EGR3 6 GO:0044706 multi-multicellular organism process 5/138 220/18722 0.0236064105884001 0.115663099766756 FOS/JUNB/PTGS2/FOSB/IL1B 5 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 5/138 221/18722 0.0240145160909182 0.116970017151677 TRIB1/GABARAPL2/GPX1/UBB/PLK3 5 GO:0010212 response to ionizing radiation 4/138 148/18722 0.0240198653956532 0.116970017151677 EGR1/GPX1/ANXA1/RHOB 4 GO:0010921 regulation of phosphatase activity 3/138 84/18722 0.0242064665259234 0.116970017151677 PPP1R15A/PLEK/PPP1R15B 3 GO:1900542 regulation of purine nucleotide metabolic process 3/138 84/18722 0.0242064665259234 0.116970017151677 DDIT4/SNCA/HIF1A 3 GO:0042886 amide transport 6/138 301/18722 0.0242303505259612 0.116970017151677 SERP1/MIDN/HIF1A/IL1B/ANXA1/IRS2 6 GO:0031667 response to nutrient levels 8/138 474/18722 0.02432477996746 0.116970017151677 PTGS2/ZFP36/GABARAPL2/LDHA/AOC1/JUN/SRSF2/FAS 8 GO:0001881 receptor recycling 2/138 33/18722 0.024533136281282 0.116970017151677 SNCA/CHMP5 2 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 2/138 33/18722 0.024533136281282 0.116970017151677 HIF1A/IL1B 2 GO:0036336 dendritic cell migration 2/138 33/18722 0.024533136281282 0.116970017151677 HMGB1/CXCR4 2 GO:0045920 negative regulation of exocytosis 2/138 33/18722 0.024533136281282 0.116970017151677 SNCA/ANXA1 2 GO:1901099 negative regulation of signal transduction in absence of ligand 2/138 33/18722 0.024533136281282 0.116970017151677 MCL1/IL1B 2 GO:1901976 regulation of cell cycle checkpoint 2/138 33/18722 0.024533136281282 0.116970017151677 DUSP1/PPP1R10 2 GO:1903146 regulation of autophagy of mitochondrion 2/138 33/18722 0.024533136281282 0.116970017151677 BNIP3L/HIF1A 2 GO:1903715 regulation of aerobic respiration 2/138 33/18722 0.024533136281282 0.116970017151677 SNCA/HIF1A 2 GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 2/138 33/18722 0.024533136281282 0.116970017151677 MCL1/IL1B 2 GO:0009411 response to UV 4/138 149/18722 0.0245456306204022 0.116970017151677 PTGS2/GPX1/BCL3/HMGN1 4 GO:0050920 regulation of chemotaxis 5/138 223/18722 0.0248443471243662 0.118135939090696 DUSP1/CXCL8/HMGB1/CXCR4/MIF 5 GO:0051222 positive regulation of protein transport 6/138 303/18722 0.0249266285610397 0.118135939090696 PTGS2/SERP1/HIF1A/IL1B/PLK3/IRS2 6 GO:0002709 regulation of T cell mediated immunity 3/138 85/18722 0.0249600906163599 0.118135939090696 HMGB1/IL1B/CD55 3 GO:0055072 iron ion homeostasis 3/138 85/18722 0.0249600906163599 0.118135939090696 HIF1A/FTH1/ALAS2 3 GO:0043535 regulation of blood vessel endothelial cell migration 4/138 151/18722 0.0256179748555436 0.120801447931489 PTGS2/HMGB1/HIF1A/ANXA1 4 GO:0034284 response to monosaccharide 5/138 225/18722 0.0256924407329402 0.120801447931489 EGR1/PTGS2/LDHA/HIF1A/IRS2 5 GO:0050769 positive regulation of neurogenesis 5/138 225/18722 0.0256924407329402 0.120801447931489 FN1/CXCR4/HIF1A/IL1B/SKIL 5 GO:0006140 regulation of nucleotide metabolic process 3/138 86/18722 0.0257262837884516 0.120801447931489 DDIT4/SNCA/HIF1A 3 GO:0014072 response to isoquinoline alkaloid 2/138 34/18722 0.0259424746693042 0.120801447931489 FOSB/CXCR4 2 GO:0032770 positive regulation of monooxygenase activity 2/138 34/18722 0.0259424746693042 0.120801447931489 HIF1A/IL1B 2 GO:0043278 response to morphine 2/138 34/18722 0.0259424746693042 0.120801447931489 FOSB/CXCR4 2 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 2/138 34/18722 0.0259424746693042 0.120801447931489 DDX5/MIF 2 GO:1904893 negative regulation of receptor signaling pathway via STAT 2/138 34/18722 0.0259424746693042 0.120801447931489 SOCS3/BCL3 2 GO:0042176 regulation of protein catabolic process 7/138 391/18722 0.0259573359191629 0.120801447931489 TRIB1/GABARAPL2/GPX1/SNCA/IL1B/UBB/PLK3 7 GO:0030509 BMP signaling pathway 4/138 152/18722 0.0261645877008175 0.121562683758556 EGR1/DDX5/FBN1/SKIL 4 GO:0019915 lipid storage 3/138 87/18722 0.0265050371673513 0.122530761522822 NFKBIA/IL1B/PLIN2 3 GO:0044070 regulation of anion transport 3/138 87/18722 0.0265050371673513 0.122530761522822 CEBPB/SNCA/IL1B 3 GO:1903578 regulation of ATP metabolic process 3/138 87/18722 0.0265050371673513 0.122530761522822 DDIT4/SNCA/HIF1A 3 GO:0022604 regulation of cell morphogenesis 6/138 309/18722 0.0270955158681671 0.124594356096933 FN1/MYH9/CXCR4/ANXA1/FGD3/RHOB 6 GO:0016052 carbohydrate catabolic process 4/138 154/18722 0.0272787742392248 0.124594356096933 DDIT4/LDHA/HMGB1/HIF1A 4 GO:0001893 maternal placenta development 2/138 35/18722 0.0273839531684481 0.124594356096933 JUNB/PTGS2 2 GO:0018149 peptide cross-linking 2/138 35/18722 0.0273839531684481 0.124594356096933 FN1/ANXA1 2 GO:0032350 regulation of hormone metabolic process 2/138 35/18722 0.0273839531684481 0.124594356096933 EGR1/HIF1A 2 GO:0034405 response to fluid shear stress 2/138 35/18722 0.0273839531684481 0.124594356096933 PTGS2/KLF2 2 GO:0035633 maintenance of blood-brain barrier 2/138 35/18722 0.0273839531684481 0.124594356096933 PTGS2/ACTG1 2 GO:0045454 cell redox homeostasis 2/138 35/18722 0.0273839531684481 0.124594356096933 GPX1/PRDX6 2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 2/138 35/18722 0.0273839531684481 0.124594356096933 PTGS2/ANXA1 2 GO:0045444 fat cell differentiation 5/138 229/18722 0.0274438879940425 0.124594356096933 PTGS2/ZFP36/CEBPB/GPX1/LRG1 5 GO:0071356 cellular response to tumor necrosis factor 5/138 229/18722 0.0274438879940425 0.124594356096933 CXCL8/NFKBIA/ZFP36/KLF2/FAS 5 GO:0051781 positive regulation of cell division 3/138 89/18722 0.0281001786204759 0.127159019676072 OSM/YBX1/IL1B 3 GO:1900407 regulation of cellular response to oxidative stress 3/138 89/18722 0.0281001786204759 0.127159019676072 GPX1/MCL1/HIF1A 3 GO:0009267 cellular response to starvation 4/138 156/18722 0.0284210063989992 0.128402046766907 GABARAPL2/AOC1/JUN/FAS 4 GO:0010594 regulation of endothelial cell migration 5/138 232/18722 0.0288062668709131 0.129114326468962 PTGS2/HMGB1/HIF1A/ANXA1/RHOB 5 GO:0030224 monocyte differentiation 2/138 36/18722 0.0288570287688445 0.129114326468962 JUN/MYH9 2 GO:0042092 type 2 immune response 2/138 36/18722 0.0288570287688445 0.129114326468962 ANXA1/BCL3 2 GO:0051385 response to mineralocorticoid 2/138 36/18722 0.0288570287688445 0.129114326468962 FOS/FOSB 2 GO:0070873 regulation of glycogen metabolic process 2/138 36/18722 0.0288570287688445 0.129114326468962 HMGB1/IRS2 2 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 2/138 36/18722 0.0288570287688445 0.129114326468962 SKIL/MIF 2 GO:0046031 ADP metabolic process 3/138 90/18722 0.0289165386440448 0.129143105476052 DDIT4/LDHA/HIF1A 3 GO:0051017 actin filament bundle assembly 4/138 157/18722 0.0290026737055452 0.129143105476052 PLEK/ACTG1/GPR65/PHACTR1 4 GO:0051250 negative regulation of lymphocyte activation 4/138 157/18722 0.0290026737055452 0.129143105476052 CEBPB/SAMSN1/HMGB1/ANXA1 4 GO:0045582 positive regulation of T cell differentiation 3/138 91/18722 0.0297454028549551 0.132238747836007 NFKBIZ/ANXA1/EGR3 3 GO:0006959 humoral immune response 6/138 317/18722 0.0301774931563995 0.133063182879769 CXCL8/TREM1/IL1B/CD55/CXCL1/BCL3 6 GO:0010506 regulation of autophagy 6/138 317/18722 0.0301774931563995 0.133063182879769 BNIP3L/SNCA/HMGB1/MCL1/HIF1A/PLK3 6 GO:0002699 positive regulation of immune effector process 5/138 235/18722 0.0302108634452448 0.133063182879769 NFKBIZ/DDX21/IL1B/ANXA1/CD55 5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 2/138 37/18722 0.0303611646168356 0.133063182879769 ETF1/GSPT1 2 GO:0002369 T cell cytokine production 2/138 37/18722 0.0303611646168356 0.133063182879769 IL1B/CD55 2 GO:0002724 regulation of T cell cytokine production 2/138 37/18722 0.0303611646168356 0.133063182879769 IL1B/CD55 2 GO:0032570 response to progesterone 2/138 37/18722 0.0303611646168356 0.133063182879769 FOS/FOSB 2 GO:0042401 cellular biogenic amine biosynthetic process 2/138 37/18722 0.0303611646168356 0.133063182879769 SAT1/SNCA 2 GO:0043403 skeletal muscle tissue regeneration 2/138 37/18722 0.0303611646168356 0.133063182879769 GPX1/ANXA1 2 GO:1903312 negative regulation of mRNA metabolic process 3/138 92/18722 0.0305867523229463 0.133841087601823 ZFP36/YBX1/SAP18 3 GO:1904951 positive regulation of establishment of protein localization 6/138 319/18722 0.030982502332347 0.135359974868009 PTGS2/SERP1/HIF1A/IL1B/PLK3/IRS2 6 GO:0034655 nucleobase-containing compound catabolic process 7/138 407/18722 0.0313147185286384 0.136596961857681 BTG2/ZFP36/DDX5/YBX1/ETF1/GSPT1/PDE4B 7 GO:0061572 actin filament bundle organization 4/138 161/18722 0.031399967273505 0.136717337204896 PLEK/ACTG1/GPR65/PHACTR1 4 GO:0032755 positive regulation of interleukin-6 production 3/138 93/18722 0.0314405662275003 0.136717337204896 HMGB1/IL1B/AKIRIN2 3 GO:0001825 blastocyst formation 2/138 38/18722 0.0318958299548107 0.137835550876146 JUNB/SKIL 2 GO:0009309 amine biosynthetic process 2/138 38/18722 0.0318958299548107 0.137835550876146 SAT1/SNCA 2 GO:0030279 negative regulation of ossification 2/138 38/18722 0.0318958299548107 0.137835550876146 SRGN/HIF1A 2 GO:0032717 negative regulation of interleukin-8 production 2/138 38/18722 0.0318958299548107 0.137835550876146 ANXA1/BCL3 2 GO:0002042 cell migration involved in sprouting angiogenesis 3/138 94/18722 0.0323068218968344 0.139395171068047 PTGS2/ANXA1/EGR3 3 GO:0050657 nucleic acid transport 4/138 163/18722 0.0326411372089883 0.140402294980857 ZFP36/YBX1/HNRNPA3/HNRNPA2B1 4 GO:0050658 RNA transport 4/138 163/18722 0.0326411372089883 0.140402294980857 ZFP36/YBX1/HNRNPA3/HNRNPA2B1 4 GO:0007044 cell-substrate junction assembly 3/138 95/18722 0.0331854948463574 0.142303901629295 FN1/TLN1/ACTG1 3 GO:0036473 cell death in response to oxidative stress 3/138 95/18722 0.0331854948463574 0.142303901629295 GPX1/MCL1/HIF1A 3 GO:0050792 regulation of viral process 4/138 164/18722 0.0332723854462938 0.142456997995439 CXCL8/ZFP36/DDX5/CXCR4 4 GO:0032506 cytokinetic process 2/138 39/18722 0.0334605000615837 0.142822962686177 MYH9/CHMP5 2 GO:0045622 regulation of T-helper cell differentiation 2/138 39/18722 0.0334605000615837 0.142822962686177 NFKBIZ/ANXA1 2 GO:1903320 regulation of protein modification by small protein conjugation or removal 5/138 242/18722 0.0336542498396582 0.143429980557073 EGR1/IVNS1ABP/HIF1A/UBB/UBE2S 5 GO:0071772 response to BMP 4/138 165/18722 0.0339107531469372 0.144081871767826 EGR1/DDX5/FBN1/SKIL 4 GO:0071773 cellular response to BMP stimulus 4/138 165/18722 0.0339107531469372 0.144081871767826 EGR1/DDX5/FBN1/SKIL 4 GO:0002718 regulation of cytokine production involved in immune response 3/138 96/18722 0.0340765588165943 0.144345606067857 DDX21/IL1B/CD55 3 GO:0034620 cellular response to unfolded protein 3/138 96/18722 0.0340765588165943 0.144345606067857 PPP1R15A/SERP1/PPP1R15B 3 GO:0016032 viral process 7/138 415/18722 0.0342538287894309 0.144875996232502 CXCL8/ZFP36/DDX5/JUN/CXCR4/CD55/CHMP5 7 GO:0002831 regulation of response to biotic stimulus 6/138 327/18722 0.0343429352028115 0.145032456251023 TRIB1/HMGB1/RIOK3/CD55/HMGB2/AKIRIN2 6 GO:0051236 establishment of RNA localization 4/138 166/18722 0.0345562474579514 0.145712176781028 ZFP36/YBX1/HNRNPA3/HNRNPA2B1 4 GO:0043255 regulation of carbohydrate biosynthetic process 3/138 97/18722 0.0349799858105871 0.146043575128708 PLEK/SNCA/IRS2 3 GO:0070167 regulation of biomineral tissue development 3/138 97/18722 0.0349799858105871 0.146043575128708 CEBPB/SRGN/HIF1A 3 GO:0120162 positive regulation of cold-induced thermogenesis 3/138 97/18722 0.0349799858105871 0.146043575128708 G0S2/CEBPB/CXCR4 3 GO:0030866 cortical actin cytoskeleton organization 2/138 40/18722 0.0350546561933082 0.146043575128708 PLEK/TLN1 2 GO:0031111 negative regulation of microtubule polymerization or depolymerization 2/138 40/18722 0.0350546561933082 0.146043575128708 SNCA/MID1IP1 2 GO:0071276 cellular response to cadmium ion 2/138 40/18722 0.0350546561933082 0.146043575128708 FOS/JUN 2 GO:0150077 regulation of neuroinflammatory response 2/138 40/18722 0.0350546561933082 0.146043575128708 PTGS2/IL1B 2 GO:2000142 regulation of DNA-templated transcription, initiation 2/138 40/18722 0.0350546561933082 0.146043575128708 HMGB1/JUN 2 GO:1903034 regulation of response to wounding 4/138 167/18722 0.0352088748781781 0.146466814328804 HMGB1/ACTG1/CXCR4/ANXA1 4 GO:0031668 cellular response to extracellular stimulus 5/138 246/18722 0.0357273434547174 0.148401786320117 FOS/GABARAPL2/AOC1/JUN/FAS 5 GO:0002833 positive regulation of response to biotic stimulus 4/138 168/18722 0.0358686412619795 0.148436644103941 HMGB1/RIOK3/HMGB2/AKIRIN2 4 GO:0070301 cellular response to hydrogen peroxide 3/138 98/18722 0.035895746130777 0.148436644103941 KLF2/ANXA1/RHOB 3 GO:1902882 regulation of response to oxidative stress 3/138 98/18722 0.035895746130777 0.148436644103941 GPX1/MCL1/HIF1A 3 GO:0032102 negative regulation of response to external stimulus 7/138 420/18722 0.0361813348851981 0.149395630542294 DUSP1/TRIB1/ZFP36/GPX1/RIOK3/SOCS3/MIF 7 GO:0021543 pallium development 4/138 169/18722 0.036535551823014 0.150411894561314 BTG2/BCL2A1/HIF1A/PHACTR1 4 GO:0031214 biomineral tissue development 4/138 169/18722 0.036535551823014 0.150411894561314 PTGS2/CEBPB/SRGN/HIF1A 4 GO:0010907 positive regulation of glucose metabolic process 2/138 41/18722 0.0366777855249267 0.150485548928024 HMGB1/IRS2 2 GO:0032733 positive regulation of interleukin-10 production 2/138 41/18722 0.0366777855249267 0.150485548928024 HMGB1/BCL3 2 GO:0021537 telencephalon development 5/138 248/18722 0.0367928981262352 0.150485548928024 BTG2/BCL2A1/CXCR4/HIF1A/PHACTR1 5 GO:0006165 nucleoside diphosphate phosphorylation 3/138 99/18722 0.0368238084153734 0.150485548928024 DDIT4/LDHA/HIF1A 3 GO:0110149 regulation of biomineralization 3/138 99/18722 0.0368238084153734 0.150485548928024 CEBPB/SRGN/HIF1A 3 GO:0071560 cellular response to transforming growth factor beta stimulus 5/138 250/18722 0.0378778827308006 0.15439262200468 FOS/FBN1/JUN/LRG1/SKIL 5 GO:0110148 biomineralization 4/138 171/18722 0.0378908231509867 0.15439262200468 PTGS2/CEBPB/SRGN/HIF1A 4 GO:0030890 positive regulation of B cell proliferation 2/138 42/18722 0.0383293810921467 0.155496599970035 IRS2/MIF 2 GO:0045214 sarcomere organization 2/138 42/18722 0.0383293810921467 0.155496599970035 ACTG1/KRT19 2 GO:0046688 response to copper ion 2/138 42/18722 0.0383293810921467 0.155496599970035 SNCA/AOC1 2 GO:0006576 cellular biogenic amine metabolic process 3/138 101/18722 0.038716705324142 0.156384021650344 SAT1/SNCA/AOC1 3 GO:0046939 nucleotide phosphorylation 3/138 101/18722 0.038716705324142 0.156384021650344 DDIT4/LDHA/HIF1A 3 GO:0150115 cell-substrate junction organization 3/138 101/18722 0.038716705324142 0.156384021650344 FN1/TLN1/ACTG1 3 GO:0048568 embryonic organ development 7/138 427/18722 0.038998811863557 0.15729520784968 JUNB/CXCL8/CEBPB/FBN1/SOCS3/HIF1A/KRT19 7 GO:0000910 cytokinesis 4/138 173/18722 0.0392747179046385 0.158178784267162 MYH9/CHMP5/PLK3/RHOB 4 GO:0009743 response to carbohydrate 5/138 253/18722 0.0395419269999988 0.159024830695082 EGR1/PTGS2/LDHA/HIF1A/IRS2 5 GO:0002697 regulation of immune effector process 6/138 339/18722 0.03981240182175 0.159291680751875 NFKBIZ/HMGB1/DDX21/IL1B/ANXA1/CD55 6 GO:0045619 regulation of lymphocyte differentiation 4/138 174/18722 0.0399774054040927 0.159291680751875 NFKBIZ/HMGB1/ANXA1/EGR3 4 GO:0006509 membrane protein ectodomain proteolysis 2/138 43/18722 0.0400089417339419 0.159291680751875 MYH9/IL1B 2 GO:0034142 toll-like receptor 4 signaling pathway 2/138 43/18722 0.0400089417339419 0.159291680751875 NFKBIA/HMGB1 2 GO:0046636 negative regulation of alpha-beta T cell activation 2/138 43/18722 0.0400089417339419 0.159291680751875 HMGB1/ANXA1 2 GO:1903793 positive regulation of anion transport 2/138 43/18722 0.0400089417339419 0.159291680751875 CEBPB/IL1B 2 GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 2/138 43/18722 0.0400089417339419 0.159291680751875 MCL1/IL1B 2 GO:0009135 purine nucleoside diphosphate metabolic process 3/138 103/18722 0.0406583937082505 0.160796330072754 DDIT4/LDHA/HIF1A 3 GO:0009179 purine ribonucleoside diphosphate metabolic process 3/138 103/18722 0.0406583937082505 0.160796330072754 DDIT4/LDHA/HIF1A 3 GO:0090277 positive regulation of peptide hormone secretion 3/138 103/18722 0.0406583937082505 0.160796330072754 SERP1/HIF1A/IRS2 3 GO:0051924 regulation of calcium ion transport 5/138 255/18722 0.0406757514808547 0.160796330072754 PTGS2/SNCA/C4orf3/CXCR4/PDE4B 5 GO:1903362 regulation of cellular protein catabolic process 5/138 255/18722 0.0406757514808547 0.160796330072754 TRIB1/GABARAPL2/GPX1/UBB/PLK3 5 GO:0052548 regulation of endopeptidase activity 7/138 432/18722 0.0410973575900676 0.162232547763345 PTGS2/PLAUR/GPX1/SNCA/HMGB1/FAS/AKIRIN2 7 GO:0071559 response to transforming growth factor beta 5/138 256/18722 0.0412500219596305 0.16260454831962 FOS/FBN1/JUN/LRG1/SKIL 5 GO:0045621 positive regulation of lymphocyte differentiation 3/138 104/18722 0.0416474396224313 0.162826858590461 NFKBIZ/ANXA1/EGR3 3 GO:0032007 negative regulation of TOR signaling 2/138 44/18722 0.0417159720355727 0.162826858590461 DDIT4/HIF1A 2 GO:0032881 regulation of polysaccharide metabolic process 2/138 44/18722 0.0417159720355727 0.162826858590461 HMGB1/IRS2 2 GO:0050999 regulation of nitric-oxide synthase activity 2/138 44/18722 0.0417159720355727 0.162826858590461 HIF1A/IL1B 2 GO:0060711 labyrinthine layer development 2/138 44/18722 0.0417159720355727 0.162826858590461 JUNB/SOCS3 2 GO:0150076 neuroinflammatory response 2/138 44/18722 0.0417159720355727 0.162826858590461 PTGS2/IL1B 2 GO:1903573 negative regulation of response to endoplasmic reticulum stress 2/138 44/18722 0.0417159720355727 0.162826858590461 PPP1R15A/PPP1R15B 2 GO:0005996 monosaccharide metabolic process 5/138 257/18722 0.0418292060491313 0.163040168676096 SERP1/MIDN/HMGB1/SLC2A3/IRS2 5 GO:0051302 regulation of cell division 4/138 177/18722 0.0421284439926894 0.163747848647562 OSM/YBX1/IL1B/PLK3 4 GO:0071466 cellular response to xenobiotic stimulus 4/138 177/18722 0.0421284439926894 0.163747848647562 RNF149/CXCR4/IL1B/PDE4B 4 GO:0032231 regulation of actin filament bundle assembly 3/138 105/18722 0.0426485663549986 0.165307743963734 PLEK/ACTG1/GPR65 3 GO:2001022 positive regulation of response to DNA damage stimulus 3/138 105/18722 0.0426485663549986 0.165307743963734 DDX5/HMGB1/SKIL 3 GO:0009266 response to temperature stimulus 4/138 178/18722 0.0428597829933754 0.16589537701052 FOS/PTGS2/NFKBIA/CXCR4 4 GO:0002920 regulation of humoral immune response 2/138 45/18722 0.0434499822721212 0.166681206854811 IL1B/CD55 2 GO:0006110 regulation of glycolytic process 2/138 45/18722 0.0434499822721212 0.166681206854811 DDIT4/HIF1A 2 GO:0032309 icosanoid secretion 2/138 45/18722 0.0434499822721212 0.166681206854811 IL1B/ANXA1 2 GO:0035307 positive regulation of protein dephosphorylation 2/138 45/18722 0.0434499822721212 0.166681206854811 PPP1R15A/PPP1R15B 2 GO:0010950 positive regulation of endopeptidase activity 4/138 179/18722 0.0435982839419973 0.166681206854811 SNCA/HMGB1/FAS/AKIRIN2 4 GO:0002793 positive regulation of peptide secretion 3/138 106/18722 0.0436617318710591 0.166681206854811 SERP1/HIF1A/IRS2 3 GO:0006090 pyruvate metabolic process 3/138 106/18722 0.0436617318710591 0.166681206854811 DDIT4/LDHA/HIF1A 3 GO:0009185 ribonucleoside diphosphate metabolic process 3/138 106/18722 0.0436617318710591 0.166681206854811 DDIT4/LDHA/HIF1A 3 GO:0030038 contractile actin filament bundle assembly 3/138 106/18722 0.0436617318710591 0.166681206854811 ACTG1/GPR65/PHACTR1 3 GO:0043149 stress fiber assembly 3/138 106/18722 0.0436617318710591 0.166681206854811 ACTG1/GPR65/PHACTR1 3 GO:0043409 negative regulation of MAPK cascade 4/138 180/18722 0.0443439452701539 0.169053698201148 DUSP1/RNF149/DUSP2/IL1B 4 GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3/138 107/18722 0.04468689274469 0.16989565916458 NFKBIZ/IL1B/CD55 3 GO:0051341 regulation of oxidoreductase activity 3/138 107/18722 0.04468689274469 0.16989565916458 SNCA/HIF1A/IL1B 3 GO:0031330 negative regulation of cellular catabolic process 5/138 262/18722 0.0447990216154561 0.170089600485422 ZFP36/GABARAPL2/SNCA/MCL1/YBX1 5 GO:0032640 tumor necrosis factor production 4/138 181/18722 0.0450967648183737 0.170488874099067 ZFP36/HMGB1/BCL3/MIF 4 GO:0032680 regulation of tumor necrosis factor production 4/138 181/18722 0.0450967648183737 0.170488874099067 ZFP36/HMGB1/BCL3/MIF 4 GO:1905952 regulation of lipid localization 4/138 181/18722 0.0450967648183737 0.170488874099067 NFKBIA/IL1B/PLIN2/IRS2 4 GO:0006984 ER-nucleus signaling pathway 2/138 46/18722 0.0452104883525374 0.170488874099067 PPP1R15A/PPP1R15B 2 GO:2000107 negative regulation of leukocyte apoptotic process 2/138 46/18722 0.0452104883525374 0.170488874099067 HIF1A/IRS2 2 GO:0045861 negative regulation of proteolysis 6/138 351/18722 0.0458078575660274 0.172507804609275 PTGS2/PLAUR/GABARAPL2/GPX1/SNCA/IL1R2 6 GO:0032868 response to insulin 5/138 264/18722 0.0460215222996049 0.173078238594325 EGR1/PTPRE/SOCS3/IL1B/IRS2 5 GO:0002456 T cell mediated immunity 3/138 109/18722 0.0467730200974629 0.175325313324054 HMGB1/IL1B/CD55 3 GO:0046700 heterocycle catabolic process 7/138 445/18722 0.0468948041140195 0.175325313324054 BTG2/ZFP36/DDX5/YBX1/ETF1/GSPT1/PDE4B 7 GO:0042311 vasodilation 2/138 47/18722 0.0469970117641912 0.175325313324054 KLF2/GPX1 2 GO:0045581 negative regulation of T cell differentiation 2/138 47/18722 0.0469970117641912 0.175325313324054 HMGB1/ANXA1 2 GO:0097028 dendritic cell differentiation 2/138 47/18722 0.0469970117641912 0.175325313324054 CEBPB/HMGB1 2 GO:1900744 regulation of p38MAPK cascade 2/138 47/18722 0.0469970117641912 0.175325313324054 DUSP1/IL1B 2 GO:1904659 glucose transmembrane transport 3/138 110/18722 0.0478338930554798 0.177970219750535 SLC2A3/IL1B/IRS2 3 GO:1905954 positive regulation of lipid localization 3/138 110/18722 0.0478338930554798 0.177970219750535 NFKBIA/IL1B/PLIN2 3 GO:0007369 gastrulation 4/138 185/18722 0.048179561584782 0.179016982497261 DUSP1/FN1/DUSP2/ETS2 4 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6/138 356/18722 0.0484636902147977 0.179832599823709 NFKBIZ/HMGB1/IL1B/ANXA1/CD55/BCL3 6 GO:0002686 negative regulation of leukocyte migration 2/138 48/18722 0.0488090795179269 0.180153406231287 DUSP1/MIF 2 GO:0048146 positive regulation of fibroblast proliferation 2/138 48/18722 0.0488090795179269 0.180153406231287 FN1/MIF 2 GO:0090199 regulation of release of cytochrome c from mitochondria 2/138 48/18722 0.0488090795179269 0.180153406231287 PLAUR/GPX1 2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 2/138 48/18722 0.0488090795179269 0.180153406231287 G0S2/SKIL 2 GO:0071706 tumor necrosis factor superfamily cytokine production 4/138 186/18722 0.048968119466808 0.180262270471067 ZFP36/HMGB1/BCL3/MIF 4 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 4/138 186/18722 0.048968119466808 0.180262270471067 ZFP36/HMGB1/BCL3/MIF 4 GO:0044270 cellular nitrogen compound catabolic process 7/138 451/18722 0.0497390851315383 0.182708027025016 BTG2/ZFP36/DDX5/YBX1/ETF1/GSPT1/PDE4B 7 GO:0002695 negative regulation of leukocyte activation 4/138 187/18722 0.0497638104509387 0.182708027025016 CEBPB/SAMSN1/HMGB1/ANXA1 4 GO:0002821 positive regulation of adaptive immune response 3/138 112/18722 0.0499910141929236 0.183300385374053 NFKBIZ/IL1B/CD55 3 GO:0002762 negative regulation of myeloid leukocyte differentiation 2/138 49/18722 0.0506462240936141 0.18448748907399 TRIB1/FBN1 2 GO:0009409 response to cold 2/138 49/18722 0.0506462240936141 0.18448748907399 FOS/NFKBIA 2 GO:0043330 response to exogenous dsRNA 2/138 49/18722 0.0506462240936141 0.18448748907399 NFKBIA/DDX21 2 GO:0043457 regulation of cellular respiration 2/138 49/18722 0.0506462240936141 0.18448748907399 SNCA/HIF1A 2 GO:0060964 regulation of gene silencing by miRNA 2/138 49/18722 0.0506462240936141 0.18448748907399 ZFP36/DDX5 2 GO:0044106 cellular amine metabolic process 3/138 113/18722 0.0510871613469403 0.185690172559626 SAT1/SNCA/AOC1 3 GO:0051962 positive regulation of nervous system development 5/138 272/18722 0.0511098354943133 0.185690172559626 FN1/CXCR4/HIF1A/IL1B/SKIL 5 GO:0008645 hexose transmembrane transport 3/138 114/18722 0.0521949635607937 0.18879808496612 SLC2A3/IL1B/IRS2 3 GO:0021987 cerebral cortex development 3/138 114/18722 0.0521949635607937 0.18879808496612 BCL2A1/HIF1A/PHACTR1 3 GO:0001961 positive regulation of cytokine-mediated signaling pathway 2/138 50/18722 0.0525079833861937 0.18879808496612 CXCR4/HIF1A 2 GO:0019083 viral transcription 2/138 50/18722 0.0525079833861937 0.18879808496612 ZFP36/JUN 2 GO:0046638 positive regulation of alpha-beta T cell differentiation 2/138 50/18722 0.0525079833861937 0.18879808496612 NFKBIZ/ANXA1 2 GO:0051646 mitochondrion localization 2/138 50/18722 0.0525079833861937 0.18879808496612 HIF1A/UBB 2 GO:0070231 T cell apoptotic process 2/138 50/18722 0.0525079833861937 0.18879808496612 HIF1A/FAS 2 GO:1902930 regulation of alcohol biosynthetic process 2/138 50/18722 0.0525079833861937 0.18879808496612 PLEK/SNCA 2 GO:0050767 regulation of neurogenesis 6/138 364/18722 0.0529080231235791 0.189991004326349 FN1/CXCR4/HIF1A/IL1B/SKIL/HMGB2 6 GO:0043279 response to alkaloid 3/138 115/18722 0.0533143673952632 0.19095738025871 SNCA/FOSB/CXCR4 3 GO:0046916 cellular transition metal ion homeostasis 3/138 115/18722 0.0533143673952632 0.19095738025871 HIF1A/FTH1/ALAS2 3 GO:0032872 regulation of stress-activated MAPK cascade 4/138 192/18722 0.0538490266246297 0.192624474416895 DUSP1/HMGB1/IL1B/FAS 4 GO:0015749 monosaccharide transmembrane transport 3/138 116/18722 0.0544453182922693 0.194031533907066 SLC2A3/IL1B/IRS2 3 GO:0035967 cellular response to topologically incorrect protein 3/138 116/18722 0.0544453182922693 0.194031533907066 PPP1R15A/SERP1/PPP1R15B 3 GO:0046034 ATP metabolic process 5/138 277/18722 0.0544515371834058 0.194031533907066 DDIT4/LDHA/SNCA/HIF1A/UQCRH 5 GO:0002285 lymphocyte activation involved in immune response 4/138 194/18722 0.0555327865975823 0.197574377724234 NFKBIZ/HMGB1/ANXA1/BCL3 4 GO:0002702 positive regulation of production of molecular mediator of immune response 3/138 117/18722 0.0555877606029735 0.197574377724234 DDX21/IL1B/CD55 3 GO:0030514 negative regulation of BMP signaling pathway 2/138 52/18722 0.0563035244568356 0.198631418218677 FBN1/SKIL 2 GO:0032206 positive regulation of telomere maintenance 2/138 52/18722 0.0563035244568356 0.198631418218677 PPP1R10/HNRNPA2B1 2 GO:0035196 production of miRNAs involved in gene silencing by miRNA 2/138 52/18722 0.0563035244568356 0.198631418218677 DDX5/HNRNPA2B1 2 GO:0043392 negative regulation of DNA binding 2/138 52/18722 0.0563035244568356 0.198631418218677 NFKBIA/JUN 2 GO:0060147 regulation of posttranscriptional gene silencing 2/138 52/18722 0.0563035244568356 0.198631418218677 ZFP36/DDX5 2 GO:0070302 regulation of stress-activated protein kinase signaling cascade 4/138 195/18722 0.0563852742747973 0.198631418218677 DUSP1/HMGB1/IL1B/FAS 4 GO:0006413 translational initiation 3/138 118/18722 0.0567416376154682 0.198631418218677 PPP1R15A/EIF1/PPP1R15B 3 GO:0007613 memory 3/138 118/18722 0.0567416376154682 0.198631418218677 PTGS2/CEBPB/SGK1 3 GO:0009308 amine metabolic process 3/138 118/18722 0.0567416376154682 0.198631418218677 SAT1/SNCA/AOC1 3 GO:0034219 carbohydrate transmembrane transport 3/138 118/18722 0.0567416376154682 0.198631418218677 SLC2A3/IL1B/IRS2 3 GO:0045446 endothelial cell differentiation 3/138 118/18722 0.0567416376154682 0.198631418218677 GPX1/CXCR4/IL1B 3 GO:1903313 positive regulation of mRNA metabolic process 3/138 118/18722 0.0567416376154682 0.198631418218677 BTG2/ZFP36/PRDX6 3 GO:0001654 eye development 6/138 371/18722 0.0569948953762021 0.199267328934636 HMGB1/FBN1/HIF1A/HMGN1/JMJD6/SKIL 6 GO:0006006 glucose metabolic process 4/138 196/18722 0.0572448199547979 0.199639516208274 SERP1/MIDN/HMGB1/IRS2 4 GO:0071674 mononuclear cell migration 4/138 196/18722 0.0572448199547979 0.199639516208274 DUSP1/HMGB1/CXCR4/ANXA1 4 GO:0019439 aromatic compound catabolic process 7/138 467/18722 0.0578526985658247 0.200978472516624 BTG2/ZFP36/DDX5/YBX1/ETF1/GSPT1/PDE4B 7 GO:0010906 regulation of glucose metabolic process 3/138 119/18722 0.0579068915820626 0.200978472516624 MIDN/HMGB1/IRS2 3 GO:0030282 bone mineralization 3/138 119/18722 0.0579068915820626 0.200978472516624 PTGS2/SRGN/HIF1A 3 GO:1903532 positive regulation of secretion by cell 5/138 282/18722 0.0579176194604142 0.200978472516624 SERP1/SNCA/HIF1A/IL1B/IRS2 5 GO:0007566 embryo implantation 2/138 53/18722 0.0582364086213602 0.201081793043729 PTGS2/IL1B 2 GO:0060966 regulation of gene silencing by RNA 2/138 53/18722 0.0582364086213602 0.201081793043729 ZFP36/DDX5 2 GO:0071715 icosanoid transport 2/138 53/18722 0.0582364086213602 0.201081793043729 IL1B/ANXA1 2 GO:1903202 negative regulation of oxidative stress-induced cell death 2/138 53/18722 0.0582364086213602 0.201081793043729 GPX1/HIF1A 2 GO:0051146 striated muscle cell differentiation 5/138 283/18722 0.0586257581855821 0.20217532221868 GPX1/ACTG1/MYH9/YBX1/KRT19 5 GO:0150063 visual system development 6/138 375/18722 0.0594136092581261 0.204638706145254 HMGB1/FBN1/HIF1A/HMGN1/JMJD6/SKIL 6 GO:0031050 dsRNA processing 2/138 54/18722 0.0601921121711776 0.206045077702813 DDX5/HNRNPA2B1 2 GO:0035065 regulation of histone acetylation 2/138 54/18722 0.0601921121711776 0.206045077702813 SNCA/IL1B 2 GO:0043647 inositol phosphate metabolic process 2/138 54/18722 0.0601921121711776 0.206045077702813 PLEK/SNCA 2 GO:0070228 regulation of lymphocyte apoptotic process 2/138 54/18722 0.0601921121711776 0.206045077702813 HIF1A/IRS2 2 GO:0070918 production of small RNA involved in gene silencing by RNA 2/138 54/18722 0.0601921121711776 0.206045077702813 DDX5/HNRNPA2B1 2 GO:0019730 antimicrobial humoral response 3/138 122/18722 0.0614703227545959 0.209904181872442 CXCL8/CXCL1/BCL3 3 GO:0050868 negative regulation of T cell activation 3/138 122/18722 0.0614703227545959 0.209904181872442 CEBPB/HMGB1/ANXA1 3 GO:0006403 RNA localization 4/138 201/18722 0.0616480159643894 0.210252976015804 ZFP36/YBX1/HNRNPA3/HNRNPA2B1 4 GO:0030900 forebrain development 6/138 379/18722 0.0618930804097303 0.210572668435549 BTG2/BCL2A1/CXCR4/HIF1A/PHACTR1/UBB 6 GO:0051346 negative regulation of hydrolase activity 6/138 379/18722 0.0618930804097303 0.210572668435549 PTGS2/PLAUR/PPP1R15A/GPX1/SNCA/ANXA1 6 GO:0001755 neural crest cell migration 2/138 55/18722 0.0621701992842292 0.210742587829488 FN1/HIF1A 2 GO:0008333 endosome to lysosome transport 2/138 55/18722 0.0621701992842292 0.210742587829488 CHMP5/RHOB 2 GO:0045620 negative regulation of lymphocyte differentiation 2/138 55/18722 0.0621701992842292 0.210742587829488 HMGB1/ANXA1 2 GO:0048880 sensory system development 6/138 381/18722 0.0631556204174383 0.213822495890184 HMGB1/FBN1/HIF1A/HMGN1/JMJD6/SKIL 6 GO:0032869 cellular response to insulin stimulus 4/138 203/18722 0.0634582768532223 0.214586129383375 PTPRE/SOCS3/IL1B/IRS2 4 GO:0071375 cellular response to peptide hormone stimulus 5/138 290/18722 0.0637218220748468 0.214904664024914 PTPRE/FBN1/SOCS3/IL1B/IRS2 5 GO:1902903 regulation of supramolecular fiber organization 6/138 382/18722 0.0637925936653464 0.214904664024914 PLEK/GPX1/SNCA/ACTG1/GPR65/MID1IP1 6 GO:0009132 nucleoside diphosphate metabolic process 3/138 124/18722 0.0639017254069305 0.214904664024914 DDIT4/LDHA/HIF1A 3 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 2/138 56/18722 0.0641702392399221 0.214904664024914 BTG2/ZFP36 2 GO:0002711 positive regulation of T cell mediated immunity 2/138 56/18722 0.0641702392399221 0.214904664024914 IL1B/CD55 2 GO:0010332 response to gamma radiation 2/138 56/18722 0.0641702392399221 0.214904664024914 EGR1/GPX1 2 GO:0048008 platelet-derived growth factor receptor signaling pathway 2/138 56/18722 0.0641702392399221 0.214904664024914 SNCA/CSRNP1 2 GO:0048255 mRNA stabilization 2/138 56/18722 0.0641702392399221 0.214904664024914 ZFP36/YBX1 2 GO:0071383 cellular response to steroid hormone stimulus 4/138 204/18722 0.0643738485972215 0.215327428661139 ZFP36/DDIT4/DDX5/ANXA1 4 GO:0010632 regulation of epithelial cell migration 5/138 292/18722 0.0652224745600039 0.217904137695667 PTGS2/HMGB1/HIF1A/ANXA1/RHOB 5 GO:0045786 negative regulation of cell cycle 6/138 385/18722 0.0657263292277826 0.219324189737313 PTGS2/DUSP1/BTG2/PPP1R10/PLK3/RHOB 6 GO:0010883 regulation of lipid storage 2/138 57/18722 0.0661918063685113 0.220085779120152 NFKBIA/PLIN2 2 GO:0033619 membrane protein proteolysis 2/138 57/18722 0.0661918063685113 0.220085779120152 MYH9/IL1B 2 GO:0060760 positive regulation of response to cytokine stimulus 2/138 57/18722 0.0661918063685113 0.220085779120152 CXCR4/HIF1A 2 GO:0051224 negative regulation of protein transport 3/138 127/18722 0.0676312430620173 0.224603519620041 MIDN/IL1B/ANXA1 3 GO:0043525 positive regulation of neuron apoptotic process 2/138 58/18722 0.068234480000941 0.225986210612434 MCL1/JUN 2 GO:0043666 regulation of phosphoprotein phosphatase activity 2/138 58/18722 0.068234480000941 0.225986210612434 PPP1R15A/PPP1R15B 2 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 3/138 128/18722 0.0688961330642533 0.225986210612434 FBN1/LRG1/SKIL 3 GO:0035303 regulation of dephosphorylation 3/138 128/18722 0.0688961330642533 0.225986210612434 PPP1R15A/PLEK/PPP1R15B 3 GO:0050866 negative regulation of cell activation 4/138 210/18722 0.0700124865151366 0.225986210612434 CEBPB/SAMSN1/HMGB1/ANXA1 4 GO:0007093 mitotic cell cycle checkpoint signaling 3/138 129/18722 0.0701717712981959 0.225986210612434 DUSP1/PPP1R10/PLK3 3 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 3/138 129/18722 0.0701717712981959 0.225986210612434 SNCA/HMGB1/FAS 3 GO:0002820 negative regulation of adaptive immune response 2/138 59/18722 0.0702978444191436 0.225986210612434 SAMSN1/CD55 2 GO:0019369 arachidonic acid metabolic process 2/138 59/18722 0.0702978444191436 0.225986210612434 PTGS2/GPX1 2 GO:0043407 negative regulation of MAP kinase activity 2/138 59/18722 0.0702978444191436 0.225986210612434 DUSP1/IL1B 2 GO:0048010 vascular endothelial growth factor receptor signaling pathway 2/138 59/18722 0.0702978444191436 0.225986210612434 HIF1A/IL1B 2 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 2/138 59/18722 0.0702978444191436 0.225986210612434 SAMSN1/SOCS3 2 GO:0006091 generation of precursor metabolites and energy 7/138 490/18722 0.0708823757833904 0.225986210612434 DDIT4/LDHA/SNCA/HMGB1/HIF1A/UQCRH/IRS2 7 GO:0043491 protein kinase B signaling 4/138 211/18722 0.0709763061347997 0.225986210612434 OSM/GPX1/IL1B/PLK3 4 GO:0006283 transcription-coupled nucleotide-excision repair 1/138 10/18722 0.0713291691848412 0.225986210612434 HMGN1 1 GO:0009750 response to fructose 1/138 10/18722 0.0713291691848412 0.225986210612434 PTGS2 1 GO:0010992 ubiquitin recycling 1/138 10/18722 0.0713291691848412 0.225986210612434 UBE2S 1 GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation 1/138 10/18722 0.0713291691848412 0.225986210612434 PPP1R15B 1 GO:0015911 long-chain fatty acid import across plasma membrane 1/138 10/18722 0.0713291691848412 0.225986210612434 IRS2 1 GO:0031915 positive regulation of synaptic plasticity 1/138 10/18722 0.0713291691848412 0.225986210612434 PTGS2 1 GO:0032070 regulation of deoxyribonuclease activity 1/138 10/18722 0.0713291691848412 0.225986210612434 HMGB1 1 GO:0033080 immature T cell proliferation in thymus 1/138 10/18722 0.0713291691848412 0.225986210612434 IL1B 1 GO:0033089 positive regulation of T cell differentiation in thymus 1/138 10/18722 0.0713291691848412 0.225986210612434 EGR3 1 GO:0033131 regulation of glucokinase activity 1/138 10/18722 0.0713291691848412 0.225986210612434 MIDN 1 GO:0045625 regulation of T-helper 1 cell differentiation 1/138 10/18722 0.0713291691848412 0.225986210612434 ANXA1 1 GO:0045898 regulation of RNA polymerase II transcription preinitiation complex assembly 1/138 10/18722 0.0713291691848412 0.225986210612434 HMGB1 1 GO:0051351 positive regulation of ligase activity 1/138 10/18722 0.0713291691848412 0.225986210612434 MID1IP1 1 GO:0070099 regulation of chemokine-mediated signaling pathway 1/138 10/18722 0.0713291691848412 0.225986210612434 HIF1A 1 GO:0072124 regulation of glomerular mesangial cell proliferation 1/138 10/18722 0.0713291691848412 0.225986210612434 EGR1 1 GO:0072203 cell proliferation involved in metanephros development 1/138 10/18722 0.0713291691848412 0.225986210612434 EGR1 1 GO:0072378 blood coagulation, fibrin clot formation 1/138 10/18722 0.0713291691848412 0.225986210612434 FN1 1 GO:0097278 complement-dependent cytotoxicity 1/138 10/18722 0.0713291691848412 0.225986210612434 CD55 1 GO:0140059 dendrite arborization 1/138 10/18722 0.0713291691848412 0.225986210612434 PHACTR1 1 GO:1904668 positive regulation of ubiquitin protein ligase activity 1/138 10/18722 0.0713291691848412 0.225986210612434 UBE2S 1 GO:1904896 ESCRT complex disassembly 1/138 10/18722 0.0713291691848412 0.225986210612434 CHMP5 1 GO:1904903 ESCRT III complex disassembly 1/138 10/18722 0.0713291691848412 0.225986210612434 CHMP5 1 GO:2000425 regulation of apoptotic cell clearance 1/138 10/18722 0.0713291691848412 0.225986210612434 HMGB1 1 GO:2000434 regulation of protein neddylation 1/138 10/18722 0.0713291691848412 0.225986210612434 HIF1A 1 GO:2000659 regulation of interleukin-1-mediated signaling pathway 1/138 10/18722 0.0713291691848412 0.225986210612434 IL1R2 1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 1/138 10/18722 0.0713291691848412 0.225986210612434 FAS 1 GO:0006352 DNA-templated transcription, initiation 3/138 130/18722 0.071458090312232 0.225986210612434 HMGB1/JUN/TAF10 3 GO:0051028 mRNA transport 3/138 130/18722 0.071458090312232 0.225986210612434 ZFP36/HNRNPA3/HNRNPA2B1 3 GO:0006469 negative regulation of protein kinase activity 4/138 212/18722 0.0719469493372731 0.227016281185523 DUSP1/TRIB1/SNCA/IL1B 4 GO:0009749 response to glucose 4/138 212/18722 0.0719469493372731 0.227016281185523 EGR1/LDHA/HIF1A/IRS2 4 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 2/138 60/18722 0.072381488806791 0.227613201524632 NFKBIA/RIOK3 2 GO:0006289 nucleotide-excision repair 2/138 60/18722 0.072381488806791 0.227613201524632 HMGB1/HMGN1 2 GO:1903670 regulation of sprouting angiogenesis 2/138 60/18722 0.072381488806791 0.227613201524632 KLF2/HMGB1 2 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 3/138 131/18722 0.0727550219164958 0.228271957151756 FBN1/LRG1/SKIL 3 GO:1904950 negative regulation of establishment of protein localization 3/138 131/18722 0.0727550219164958 0.228271957151756 MIDN/IL1B/ANXA1 3 GO:0051651 maintenance of location in cell 4/138 213/18722 0.0729243975474982 0.228545718890414 SNCA/SRGN/FTH1/MORC3 4 GO:0032970 regulation of actin filament-based process 6/138 396/18722 0.0731093445692377 0.228867610726871 PLEK/ACTG1/MYH9/GPR65/RHOB/PDE4B 6 GO:0015849 organic acid transport 5/138 303/18722 0.0738288430016747 0.229315444168382 SNCA/IL1B/ANXA1/PLIN2/IRS2 5 GO:0000082 G1/S transition of mitotic cell cycle 4/138 214/18722 0.0739086317588585 0.229315444168382 ANXA1/GSPT1/PLK3/TAF10 4 GO:1901361 organic cyclic compound catabolic process 7/138 495/18722 0.0739298060543192 0.229315444168382 BTG2/ZFP36/DDX5/YBX1/ETF1/GSPT1/PDE4B 7 GO:0007569 cell aging 3/138 132/18722 0.0740624972053083 0.229315444168382 YBX1/MORC3/MIF 3 GO:0050994 regulation of lipid catabolic process 2/138 61/18722 0.0744850072004935 0.229315444168382 IL1B/IRS2 2 GO:0090342 regulation of cell aging 2/138 61/18722 0.0744850072004935 0.229315444168382 YBX1/MIF 2 GO:0090287 regulation of cellular response to growth factor stimulus 5/138 304/18722 0.0746407008796923 0.229315444168382 FBN1/HIF1A/IL1B/LRG1/SKIL 5 GO:0031669 cellular response to nutrient levels 4/138 215/18722 0.0748996325382065 0.229315444168382 GABARAPL2/AOC1/JUN/FAS 4 GO:0046887 positive regulation of hormone secretion 3/138 133/18722 0.0753804465792746 0.229315444168382 SERP1/HIF1A/IRS2 3 GO:0032613 interleukin-10 production 2/138 62/18722 0.076607998441445 0.229315444168382 HMGB1/BCL3 2 GO:0032653 regulation of interleukin-10 production 2/138 62/18722 0.076607998441445 0.229315444168382 HMGB1/BCL3 2 GO:0032731 positive regulation of interleukin-1 beta production 2/138 62/18722 0.076607998441445 0.229315444168382 EGR1/HMGB1 2 GO:0032757 positive regulation of interleukin-8 production 2/138 62/18722 0.076607998441445 0.229315444168382 HMGB1/IL1B 2 GO:0046173 polyol biosynthetic process 2/138 62/18722 0.076607998441445 0.229315444168382 PLEK/SNCA 2 GO:0046824 positive regulation of nucleocytoplasmic transport 2/138 62/18722 0.076607998441445 0.229315444168382 PTGS2/IL1B 2 GO:0048488 synaptic vesicle endocytosis 2/138 62/18722 0.076607998441445 0.229315444168382 SNCA/ACTG1 2 GO:0060135 maternal process involved in female pregnancy 2/138 62/18722 0.076607998441445 0.229315444168382 JUNB/PTGS2 2 GO:0140238 presynaptic endocytosis 2/138 62/18722 0.076607998441445 0.229315444168382 SNCA/ACTG1 2 GO:0002705 positive regulation of leukocyte mediated immunity 3/138 134/18722 0.0767087997670436 0.229315444168382 DDX21/IL1B/CD55 3 GO:0045088 regulation of innate immune response 4/138 218/18722 0.0779130336602449 0.229315444168382 HMGB1/RIOK3/HMGB2/AKIRIN2 4 GO:0006909 phagocytosis 5/138 308/18722 0.0779369027966808 0.229315444168382 HMGB1/MYH9/IL1B/ANXA1/JMJD6 5 GO:0002732 positive regulation of dendritic cell cytokine production 1/138 11/18722 0.0781780669324093 0.229315444168382 DDX21 1 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 1/138 11/18722 0.0781780669324093 0.229315444168382 CD55 1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 1/138 11/18722 0.0781780669324093 0.229315444168382 UQCRH 1 GO:0007144 female meiosis I 1/138 11/18722 0.0781780669324093 0.229315444168382 UBB 1 GO:0010269 response to selenium ion 1/138 11/18722 0.0781780669324093 0.229315444168382 GPX1 1 GO:0010739 positive regulation of protein kinase A signaling 1/138 11/18722 0.0781780669324093 0.229315444168382 MIF 1 GO:0019372 lipoxygenase pathway 1/138 11/18722 0.0781780669324093 0.229315444168382 GPX1 1 GO:0032000 positive regulation of fatty acid beta-oxidation 1/138 11/18722 0.0781780669324093 0.229315444168382 IRS2 1 GO:0032308 positive regulation of prostaglandin secretion 1/138 11/18722 0.0781780669324093 0.229315444168382 IL1B 1 GO:0032610 interleukin-1 alpha production 1/138 11/18722 0.0781780669324093 0.229315444168382 IL1R2 1 GO:0032650 regulation of interleukin-1 alpha production 1/138 11/18722 0.0781780669324093 0.229315444168382 IL1R2 1 GO:0033083 regulation of immature T cell proliferation 1/138 11/18722 0.0781780669324093 0.229315444168382 IL1B 1 GO:0033197 response to vitamin E 1/138 11/18722 0.0781780669324093 0.229315444168382 SRSF2 1 GO:0033625 positive regulation of integrin activation 1/138 11/18722 0.0781780669324093 0.229315444168382 PLEK 1 GO:0034163 regulation of toll-like receptor 9 signaling pathway 1/138 11/18722 0.0781780669324093 0.229315444168382 HMGB1 1 GO:0034776 response to histamine 1/138 11/18722 0.0781780669324093 0.229315444168382 AOC1 1 GO:0035581 sequestering of extracellular ligand from receptor 1/138 11/18722 0.0781780669324093 0.229315444168382 FBN1 1 GO:0039530 MDA-5 signaling pathway 1/138 11/18722 0.0781780669324093 0.229315444168382 RIOK3 1 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 1/138 11/18722 0.0781780669324093 0.229315444168382 RIOK3 1 GO:0042416 dopamine biosynthetic process 1/138 11/18722 0.0781780669324093 0.229315444168382 SNCA 1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress 1/138 11/18722 0.0781780669324093 0.229315444168382 HIF1A 1 GO:0045628 regulation of T-helper 2 cell differentiation 1/138 11/18722 0.0781780669324093 0.229315444168382 ANXA1 1 GO:0045654 positive regulation of megakaryocyte differentiation 1/138 11/18722 0.0781780669324093 0.229315444168382 HMGB2 1 GO:0045657 positive regulation of monocyte differentiation 1/138 11/18722 0.0781780669324093 0.229315444168382 JUN 1 GO:0046501 protoporphyrinogen IX metabolic process 1/138 11/18722 0.0781780669324093 0.229315444168382 ALAS2 1 GO:0046643 regulation of gamma-delta T cell activation 1/138 11/18722 0.0781780669324093 0.229315444168382 EGR3 1 GO:0051610 serotonin uptake 1/138 11/18722 0.0781780669324093 0.229315444168382 SNCA 1 GO:0070243 regulation of thymocyte apoptotic process 1/138 11/18722 0.0781780669324093 0.229315444168382 HIF1A 1 GO:0070417 cellular response to cold 1/138 11/18722 0.0781780669324093 0.229315444168382 NFKBIA 1 GO:0070944 neutrophil-mediated killing of bacterium 1/138 11/18722 0.0781780669324093 0.229315444168382 TREM1 1 GO:0072110 glomerular mesangial cell proliferation 1/138 11/18722 0.0781780669324093 0.229315444168382 EGR1 1 GO:0106049 regulation of cellular response to osmotic stress 1/138 11/18722 0.0781780669324093 0.229315444168382 PTGS2 1 GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 1/138 11/18722 0.0781780669324093 0.229315444168382 PDE4B 1 GO:1903299 regulation of hexokinase activity 1/138 11/18722 0.0781780669324093 0.229315444168382 MIDN 1 GO:1905522 negative regulation of macrophage migration 1/138 11/18722 0.0781780669324093 0.229315444168382 MIF 1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 1/138 11/18722 0.0781780669324093 0.229315444168382 CEBPB 1 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 1/138 11/18722 0.0781780669324093 0.229315444168382 HMGB1 1 GO:2001053 regulation of mesenchymal cell apoptotic process 1/138 11/18722 0.0781780669324093 0.229315444168382 HIF1A 1 GO:0016239 positive regulation of macroautophagy 2/138 63/18722 0.0787500661275078 0.229315444168382 BNIP3L/HIF1A 2 GO:0030239 myofibril assembly 2/138 63/18722 0.0787500661275078 0.229315444168382 ACTG1/KRT19 2 GO:0032233 positive regulation of actin filament bundle assembly 2/138 63/18722 0.0787500661275078 0.229315444168382 PLEK/GPR65 2 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 2/138 63/18722 0.0787500661275078 0.229315444168382 CEBPB/PPP1R15A 2 GO:1902373 negative regulation of mRNA catabolic process 2/138 63/18722 0.0787500661275078 0.229315444168382 ZFP36/YBX1 2 GO:2000242 negative regulation of reproductive process 2/138 63/18722 0.0787500661275078 0.229315444168382 DUSP1/MYH9 2 GO:2000756 regulation of peptidyl-lysine acetylation 2/138 63/18722 0.0787500661275078 0.229315444168382 SNCA/IL1B 2 GO:0070372 regulation of ERK1 and ERK2 cascade 5/138 309/18722 0.0787731098185314 0.229315444168382 DUSP1/FN1/HMGB1/IL1B/MIF 5 GO:0045727 positive regulation of translation 3/138 136/18722 0.0793964332670241 0.230888478351231 PPP1R15A/SERP1/BCL3 3 GO:0051047 positive regulation of secretion 5/138 310/18722 0.0796141642209471 0.231279978107407 SERP1/SNCA/HIF1A/IL1B/IRS2 5 GO:0002064 epithelial cell development 4/138 220/18722 0.0799554255704092 0.23202914427784 GPX1/CXCR4/HIF1A/IL1B 4 GO:0006986 response to unfolded protein 3/138 137/18722 0.080755569867934 0.233341770019111 PPP1R15A/SERP1/PPP1R15B 3 GO:0050714 positive regulation of protein secretion 3/138 137/18722 0.080755569867934 0.233341770019111 SERP1/HIF1A/IRS2 3 GO:0001885 endothelial cell development 2/138 64/18722 0.0809108185657356 0.233341770019111 GPX1/IL1B 2 GO:0030888 regulation of B cell proliferation 2/138 64/18722 0.0809108185657356 0.233341770019111 IRS2/MIF 2 GO:0032507 maintenance of protein location in cell 2/138 64/18722 0.0809108185657356 0.233341770019111 SRGN/MORC3 2 GO:0055002 striated muscle cell development 2/138 64/18722 0.0809108185657356 0.233341770019111 ACTG1/KRT19 2 GO:0015931 nucleobase-containing compound transport 4/138 222/18722 0.0820243822619771 0.235236134344511 ZFP36/YBX1/HNRNPA3/HNRNPA2B1 4 GO:0055076 transition metal ion homeostasis 3/138 138/18722 0.0821248229012603 0.235236134344511 HIF1A/FTH1/ALAS2 3 GO:0046394 carboxylic acid biosynthetic process 5/138 314/18722 0.0830266918145672 0.235236134344511 PTGS2/IL1B/ANXA1/MID1IP1/MIF 5 GO:0043489 RNA stabilization 2/138 65/18722 0.083089868725329 0.235236134344511 ZFP36/YBX1 2 GO:0070613 regulation of protein processing 2/138 65/18722 0.083089868725329 0.235236134344511 MYH9/IL1R2 2 GO:0045598 regulation of fat cell differentiation 3/138 139/18722 0.0835041190507126 0.235236134344511 PTGS2/ZFP36/CEBPB 3 GO:0016053 organic acid biosynthetic process 5/138 316/18722 0.0847618206087201 0.235236134344511 PTGS2/IL1B/ANXA1/MID1IP1/MIF 5 GO:0031333 negative regulation of protein-containing complex assembly 3/138 140/18722 0.0848933844517281 0.235236134344511 SNCA/HMGB1/RIOK3 3 GO:0046165 alcohol biosynthetic process 3/138 140/18722 0.0848933844517281 0.235236134344511 PLEK/SNCA/IDI1 3 GO:0002424 T cell mediated immune response to tumor cell 1/138 12/18722 0.0849768177615113 0.235236134344511 HMGB1 1 GO:0002903 negative regulation of B cell apoptotic process 1/138 12/18722 0.0849768177615113 0.235236134344511 IRS2 1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway 1/138 12/18722 0.0849768177615113 0.235236134344511 SNCA 1 GO:0032306 regulation of prostaglandin secretion 1/138 12/18722 0.0849768177615113 0.235236134344511 IL1B 1 GO:0033079 immature T cell proliferation 1/138 12/18722 0.0849768177615113 0.235236134344511 IL1B 1 GO:0033127 regulation of histone phosphorylation 1/138 12/18722 0.0849768177615113 0.235236134344511 IL1B 1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway 1/138 12/18722 0.0849768177615113 0.235236134344511 HMGB1 1 GO:0035739 CD4-positive, alpha-beta T cell proliferation 1/138 12/18722 0.0849768177615113 0.235236134344511 CD55 1 GO:0042762 regulation of sulfur metabolic process 1/138 12/18722 0.0849768177615113 0.235236134344511 SNCA 1 GO:0043471 regulation of cellular carbohydrate catabolic process 1/138 12/18722 0.0849768177615113 0.235236134344511 HMGB1 1 GO:0045916 negative regulation of complement activation 1/138 12/18722 0.0849768177615113 0.235236134344511 CD55 1 GO:0051340 regulation of ligase activity 1/138 12/18722 0.0849768177615113 0.235236134344511 MID1IP1 1 GO:0051583 dopamine uptake involved in synaptic transmission 1/138 12/18722 0.0849768177615113 0.235236134344511 SNCA 1 GO:0051934 catecholamine uptake involved in synaptic transmission 1/138 12/18722 0.0849768177615113 0.235236134344511 SNCA 1 GO:0060123 regulation of growth hormone secretion 1/138 12/18722 0.0849768177615113 0.235236134344511 SERP1 1 GO:0060453 regulation of gastric acid secretion 1/138 12/18722 0.0849768177615113 0.235236134344511 SGK1 1 GO:0070943 neutrophil-mediated killing of symbiont cell 1/138 12/18722 0.0849768177615113 0.235236134344511 TREM1 1 GO:0071635 negative regulation of transforming growth factor beta production 1/138 12/18722 0.0849768177615113 0.235236134344511 FN1 1 GO:0072376 protein activation cascade 1/138 12/18722 0.0849768177615113 0.235236134344511 FN1 1 GO:0072520 seminiferous tubule development 1/138 12/18722 0.0849768177615113 0.235236134344511 UBB 1 GO:0097152 mesenchymal cell apoptotic process 1/138 12/18722 0.0849768177615113 0.235236134344511 HIF1A 1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress 1/138 12/18722 0.0849768177615113 0.235236134344511 JUN 1 GO:0098974 postsynaptic actin cytoskeleton organization 1/138 12/18722 0.0849768177615113 0.235236134344511 ACTG1 1 GO:1901894 regulation of ATPase-coupled calcium transmembrane transporter activity 1/138 12/18722 0.0849768177615113 0.235236134344511 C4orf3 1 GO:1903599 positive regulation of autophagy of mitochondrion 1/138 12/18722 0.0849768177615113 0.235236134344511 HIF1A 1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA 1/138 12/18722 0.0849768177615113 0.235236134344511 DDX5 1 GO:2000561 regulation of CD4-positive, alpha-beta T cell proliferation 1/138 12/18722 0.0849768177615113 0.235236134344511 CD55 1 GO:2001204 regulation of osteoclast development 1/138 12/18722 0.0849768177615113 0.235236134344511 FBN1 1 GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 2/138 66/18722 0.0852868341910212 0.235236134344511 HMGB1/HMGB2 2 GO:0006303 double-strand break repair via nonhomologous end joining 2/138 66/18722 0.0852868341910212 0.235236134344511 HMGB1/HMGB2 2 GO:0014015 positive regulation of gliogenesis 2/138 66/18722 0.0852868341910212 0.235236134344511 CXCR4/IL1B 2 GO:0016444 somatic cell DNA recombination 2/138 66/18722 0.0852868341910212 0.235236134344511 HMGB1/HMGB2 2 GO:0042446 hormone biosynthetic process 2/138 66/18722 0.0852868341910212 0.235236134344511 EGR1/HIF1A 2 GO:0050922 negative regulation of chemotaxis 2/138 66/18722 0.0852868341910212 0.235236134344511 DUSP1/MIF 2 GO:1905953 negative regulation of lipid localization 2/138 66/18722 0.0852868341910212 0.235236134344511 NFKBIA/IRS2 2 GO:0019058 viral life cycle 5/138 317/18722 0.0856365694460971 0.235966903731176 CXCL8/DDX5/CXCR4/CD55/CHMP5 5 GO:0002703 regulation of leukocyte mediated immunity 4/138 226/18722 0.0862412648382408 0.236603105350391 HMGB1/DDX21/IL1B/CD55 4 GO:0035296 regulation of tube diameter 3/138 141/18722 0.0862925447109764 0.236603105350391 PTGS2/KLF2/GPX1 3 GO:0050921 positive regulation of chemotaxis 3/138 141/18722 0.0862925447109764 0.236603105350391 CXCL8/HMGB1/CXCR4 3 GO:0097746 blood vessel diameter maintenance 3/138 141/18722 0.0862925447109764 0.236603105350391 PTGS2/KLF2/GPX1 3 GO:1903038 negative regulation of leukocyte cell-cell adhesion 3/138 141/18722 0.0862925447109764 0.236603105350391 CEBPB/HMGB1/ANXA1 3 GO:0015980 energy derivation by oxidation of organic compounds 5/138 318/18722 0.0865160952052326 0.236982571807246 SNCA/HMGB1/HIF1A/UQCRH/IRS2 5 GO:0007204 positive regulation of cytosolic calcium ion concentration 5/138 319/18722 0.0874003880853741 0.238975683215215 SNCA/HMGB1/CXCR4/GPR65/CD55 5 GO:0010517 regulation of phospholipase activity 2/138 67/18722 0.0875013371168896 0.238975683215215 SNCA/ANXA1 2 GO:1903317 regulation of protein maturation 2/138 67/18722 0.0875013371168896 0.238975683215215 MYH9/IL1R2 2 GO:0007009 plasma membrane organization 3/138 142/18722 0.0877015249255588 0.239053226119324 SERP1/MYH9/CXCR4 3 GO:0035150 regulation of tube size 3/138 142/18722 0.0877015249255588 0.239053226119324 PTGS2/KLF2/GPX1 3 GO:0034763 negative regulation of transmembrane transport 3/138 143/18722 0.0891202497019054 0.242180152672909 C4orf3/IL1B/IRS2 3 GO:0033157 regulation of intracellular protein transport 4/138 229/18722 0.0894722783840144 0.242180152672909 PTGS2/BNIP3L/IL1B/PLK3 4 GO:0046686 response to cadmium ion 2/138 68/18722 0.0897330041805888 0.242180152672909 FOS/JUN 2 GO:0051926 negative regulation of calcium ion transport 2/138 68/18722 0.0897330041805888 0.242180152672909 PTGS2/C4orf3 2 GO:0043010 camera-type eye development 5/138 322/18722 0.0900817682181119 0.242180152672909 FBN1/HIF1A/HMGN1/JMJD6/SKIL 5 GO:0106106 cold-induced thermogenesis 3/138 144/18722 0.0905486431743709 0.242180152672909 G0S2/CEBPB/CXCR4 3 GO:0120161 regulation of cold-induced thermogenesis 3/138 144/18722 0.0905486431743709 0.242180152672909 G0S2/CEBPB/CXCR4 3 GO:0001768 establishment of T cell polarity 1/138 13/18722 0.0917257861820836 0.242180152672909 MYH9 1 GO:0001778 plasma membrane repair 1/138 13/18722 0.0917257861820836 0.242180152672909 MYH9 1 GO:0006983 ER overload response 1/138 13/18722 0.0917257861820836 0.242180152672909 PPP1R15B 1 GO:0006995 cellular response to nitrogen starvation 1/138 13/18722 0.0917257861820836 0.242180152672909 GABARAPL2 1 GO:0008298 intracellular mRNA localization 1/138 13/18722 0.0917257861820836 0.242180152672909 ZFP36 1 GO:0009650 UV protection 1/138 13/18722 0.0917257861820836 0.242180152672909 GPX1 1 GO:0010745 negative regulation of macrophage derived foam cell differentiation 1/138 13/18722 0.0917257861820836 0.242180152672909 NFKBIA 1 GO:0010917 negative regulation of mitochondrial membrane potential 1/138 13/18722 0.0917257861820836 0.242180152672909 BNIP3L 1 GO:0030836 positive regulation of actin filament depolymerization 1/138 13/18722 0.0917257861820836 0.242180152672909 PLEK 1 GO:0031053 primary miRNA processing 1/138 13/18722 0.0917257861820836 0.242180152672909 HNRNPA2B1 1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 1/138 13/18722 0.0917257861820836 0.242180152672909 TRIB1 1 GO:0032429 regulation of phospholipase A2 activity 1/138 13/18722 0.0917257861820836 0.242180152672909 ANXA1 1 GO:0034112 positive regulation of homotypic cell-cell adhesion 1/138 13/18722 0.0917257861820836 0.242180152672909 PLAUR 1 GO:0034135 regulation of toll-like receptor 2 signaling pathway 1/138 13/18722 0.0917257861820836 0.242180152672909 HMGB1 1 GO:0042492 gamma-delta T cell differentiation 1/138 13/18722 0.0917257861820836 0.242180152672909 EGR3 1 GO:0043562 cellular response to nitrogen levels 1/138 13/18722 0.0917257861820836 0.242180152672909 GABARAPL2 1 GO:0051451 myoblast migration 1/138 13/18722 0.0917257861820836 0.242180152672909 ANXA1 1 GO:0060670 branching involved in labyrinthine layer morphogenesis 1/138 13/18722 0.0917257861820836 0.242180152672909 SOCS3 1 GO:0060707 trophoblast giant cell differentiation 1/138 13/18722 0.0917257861820836 0.242180152672909 SOCS3 1 GO:0070486 leukocyte aggregation 1/138 13/18722 0.0917257861820836 0.242180152672909 IL1B 1 GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 1/138 13/18722 0.0917257861820836 0.242180152672909 PDE4B 1 GO:1900115 extracellular regulation of signal transduction 1/138 13/18722 0.0917257861820836 0.242180152672909 FBN1 1 GO:1900116 extracellular negative regulation of signal transduction 1/138 13/18722 0.0917257861820836 0.242180152672909 FBN1 1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 1/138 13/18722 0.0917257861820836 0.242180152672909 SKIL 1 GO:1902947 regulation of tau-protein kinase activity 1/138 13/18722 0.0917257861820836 0.242180152672909 EGR1 1 GO:2000318 positive regulation of T-helper 17 type immune response 1/138 13/18722 0.0917257861820836 0.242180152672909 NFKBIZ 1 GO:0045669 positive regulation of osteoblast differentiation 2/138 69/18722 0.0919814665380038 0.242180152672909 CEBPB/JUND 2 GO:0050805 negative regulation of synaptic transmission 2/138 69/18722 0.0919814665380038 0.242180152672909 PTGS2/IL1B 2 GO:1901224 positive regulation of NIK/NF-kappaB signaling 2/138 69/18722 0.0919814665380038 0.242180152672909 HMGB1/IL1B 2 GO:0072594 establishment of protein localization to organelle 6/138 422/18722 0.0923761554617934 0.24298945241037 PTGS2/NFKBIA/BNIP3L/PPP1R10/FAM53C/BCL3 6 GO:0007043 cell-cell junction assembly 3/138 146/18722 0.0934341304942249 0.245540307049507 TLN1/ACTG1/IL1B 3 GO:0044772 mitotic cell cycle phase transition 6/138 424/18722 0.0939627063809819 0.246696426281389 DUSP1/ANXA1/GSPT1/PLK3/TAF10/UBE2S 6 GO:0001889 liver development 3/138 147/18722 0.0948910704132133 0.247995672502946 CEBPB/ANXA1/TAF10 3 GO:0045930 negative regulation of mitotic cell cycle 4/138 235/18722 0.0961071365460855 0.247995672502946 DUSP1/BTG2/PPP1R10/PLK3 4 GO:0070507 regulation of microtubule cytoskeleton organization 3/138 148/18722 0.0963573712066801 0.247995672502946 SNCA/CHMP5/MID1IP1 3 GO:2001056 positive regulation of cysteine-type endopeptidase activity 3/138 148/18722 0.0963573712066801 0.247995672502946 SNCA/HMGB1/FAS 3 GO:0000281 mitotic cytokinesis 2/138 71/18722 0.0965273238794842 0.247995672502946 CHMP5/RHOB 2 GO:0048762 mesenchymal cell differentiation 4/138 236/18722 0.0972350440413988 0.247995672502946 FN1/DDX5/HIF1A/IL1B 4 GO:0070371 ERK1 and ERK2 cascade 5/138 330/18722 0.0974392239407076 0.247995672502946 DUSP1/FN1/HMGB1/IL1B/MIF 5 GO:0032368 regulation of lipid transport 3/138 149/18722 0.0978329549173569 0.247995672502946 NFKBIA/IL1B/IRS2 3 GO:0019318 hexose metabolic process 4/138 237/18722 0.0983691927862654 0.247995672502946 SERP1/MIDN/HMGB1/IRS2 4 GO:0071214 cellular response to abiotic stimulus 5/138 331/18722 0.0983798808623714 0.247995672502946 EGR1/PTGS2/IL1B/RHOB/FAS 5 GO:0104004 cellular response to environmental stimulus 5/138 331/18722 0.0983798808623714 0.247995672502946 EGR1/PTGS2/IL1B/RHOB/FAS 5 GO:0000212 meiotic spindle organization 1/138 14/18722 0.0984253340738401 0.247995672502946 MYH9 1 GO:0001767 establishment of lymphocyte polarity 1/138 14/18722 0.0984253340738401 0.247995672502946 MYH9 1 GO:0001921 positive regulation of receptor recycling 1/138 14/18722 0.0984253340738401 0.247995672502946 SNCA 1 GO:0002467 germinal center formation 1/138 14/18722 0.0984253340738401 0.247995672502946 BCL3 1 GO:0002829 negative regulation of type 2 immune response 1/138 14/18722 0.0984253340738401 0.247995672502946 ANXA1 1 GO:0006596 polyamine biosynthetic process 1/138 14/18722 0.0984253340738401 0.247995672502946 SAT1 1 GO:0009214 cyclic nucleotide catabolic process 1/138 14/18722 0.0984253340738401 0.247995672502946 PDE4B 1 GO:0018158 protein oxidation 1/138 14/18722 0.0984253340738401 0.247995672502946 GPX1 1 GO:0030213 hyaluronan biosynthetic process 1/138 14/18722 0.0984253340738401 0.247995672502946 IL1B 1 GO:0031115 negative regulation of microtubule polymerization 1/138 14/18722 0.0984253340738401 0.247995672502946 SNCA 1 GO:0032688 negative regulation of interferon-beta production 1/138 14/18722 0.0984253340738401 0.247995672502946 REL 1 GO:0034616 response to laminar fluid shear stress 1/138 14/18722 0.0984253340738401 0.247995672502946 KLF2 1 GO:0036295 cellular response to increased oxygen levels 1/138 14/18722 0.0984253340738401 0.247995672502946 FAS 1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 1/138 14/18722 0.0984253340738401 0.247995672502946 DDX5 1 GO:0043922 negative regulation by host of viral transcription 1/138 14/18722 0.0984253340738401 0.247995672502946 JUN 1 GO:0045820 negative regulation of glycolytic process 1/138 14/18722 0.0984253340738401 0.247995672502946 DDIT4 1 GO:0045837 negative regulation of membrane potential 1/138 14/18722 0.0984253340738401 0.247995672502946 BNIP3L 1 GO:0047484 regulation of response to osmotic stress 1/138 14/18722 0.0984253340738401 0.247995672502946 PTGS2 1 GO:0048148 behavioral response to cocaine 1/138 14/18722 0.0984253340738401 0.247995672502946 SNCA 1 GO:0050930 induction of positive chemotaxis 1/138 14/18722 0.0984253340738401 0.247995672502946 CXCL8 1 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain 1/138 14/18722 0.0984253340738401 0.247995672502946 CXCR4 1 GO:0051589 negative regulation of neurotransmitter transport 1/138 14/18722 0.0984253340738401 0.247995672502946 SNCA 1 GO:0060354 negative regulation of cell adhesion molecule production 1/138 14/18722 0.0984253340738401 0.247995672502946 CXCL8 1 GO:0060576 intestinal epithelial cell development 1/138 14/18722 0.0984253340738401 0.247995672502946 HIF1A 1 GO:0060732 positive regulation of inositol phosphate biosynthetic process 1/138 14/18722 0.0984253340738401 0.247995672502946 SNCA 1 GO:0061043 regulation of vascular wound healing 1/138 14/18722 0.0984253340738401 0.247995672502946 CXCR4 1 GO:0070942 neutrophil mediated cytotoxicity 1/138 14/18722 0.0984253340738401 0.247995672502946 TREM1 1 GO:0086103 G protein-coupled receptor signaling pathway involved in heart process 1/138 14/18722 0.0984253340738401 0.247995672502946 PDE4B 1 GO:0099188 postsynaptic cytoskeleton organization 1/138 14/18722 0.0984253340738401 0.247995672502946 ACTG1 1 GO:1901077 regulation of relaxation of muscle 1/138 14/18722 0.0984253340738401 0.247995672502946 PDE4B 1 GO:1901722 regulation of cell proliferation involved in kidney development 1/138 14/18722 0.0984253340738401 0.247995672502946 EGR1 1 GO:1902036 regulation of hematopoietic stem cell differentiation 1/138 14/18722 0.0984253340738401 0.247995672502946 OSM 1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/138 14/18722 0.0984253340738401 0.247995672502946 MIF 1 GO:0002534 cytokine production involved in inflammatory response 2/138 72/18722 0.0988240031641276 0.247995672502946 HIF1A/IL1R2 2 GO:0005977 glycogen metabolic process 2/138 72/18722 0.0988240031641276 0.247995672502946 HMGB1/IRS2 2 GO:0042246 tissue regeneration 2/138 72/18722 0.0988240031641276 0.247995672502946 GPX1/ANXA1 2 GO:0071479 cellular response to ionizing radiation 2/138 72/18722 0.0988240031641276 0.247995672502946 EGR1/RHOB 2 GO:1900015 regulation of cytokine production involved in inflammatory response 2/138 72/18722 0.0988240031641276 0.247995672502946 HIF1A/IL1R2 2 GO:0001959 regulation of cytokine-mediated signaling pathway 3/138 150/18722 0.0993177432214095 0.248786030049669 CXCR4/HIF1A/IL1R2 3 GO:0061008 hepaticobiliary system development 3/138 150/18722 0.0993177432214095 0.248786030049669 CEBPB/ANXA1/TAF10 3 GO:0044409 entry into host 3/138 151/18722 0.100811657445042 0.251979961262261 CXCL8/CXCR4/CD55 3 GO:0048592 eye morphogenesis 3/138 151/18722 0.100811657445042 0.251979961262261 FBN1/HIF1A/HMGN1 3 GO:0006073 cellular glucan metabolic process 2/138 73/18722 0.10113604625582 0.251979961262261 HMGB1/IRS2 2 GO:0032732 positive regulation of interleukin-1 production 2/138 73/18722 0.10113604625582 0.251979961262261 EGR1/HMGB1 2 GO:0035924 cellular response to vascular endothelial growth factor stimulus 2/138 73/18722 0.10113604625582 0.251979961262261 ANXA1/EGR3 2 GO:0044042 glucan metabolic process 2/138 73/18722 0.10113604625582 0.251979961262261 HMGB1/IRS2 2 GO:0008643 carbohydrate transport 3/138 152/18722 0.102314618580832 0.25318269179422 SLC2A3/IL1B/IRS2 3 GO:0016573 histone acetylation 3/138 152/18722 0.102314618580832 0.25318269179422 SNCA/IL1B/TAF10 3 GO:0044843 cell cycle G1/S phase transition 4/138 241/18722 0.102967638327006 0.25318269179422 ANXA1/GSPT1/PLK3/TAF10 4 GO:0010822 positive regulation of mitochondrion organization 2/138 74/18722 0.103463106035778 0.25318269179422 PLAUR/HIF1A 2 GO:0046323 glucose import 2/138 74/18722 0.103463106035778 0.25318269179422 SLC2A3/IRS2 2 GO:0051881 regulation of mitochondrial membrane potential 2/138 74/18722 0.103463106035778 0.25318269179422 BNIP3L/UBB 2 GO:0070972 protein localization to endoplasmic reticulum 2/138 74/18722 0.103463106035778 0.25318269179422 PPP1R15A/GABARAPL2 2 GO:0048732 gland development 6/138 436/18722 0.103789751064863 0.25318269179422 CEBPB/GPX1/HIF1A/ANXA1/TAF10/IRS2 6 GO:0120254 olefinic compound metabolic process 3/138 153/18722 0.103826547303797 0.25318269179422 EGR1/PTGS2/GPX1 3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/138 15/18722 0.105075820705111 0.25318269179422 RPL7 1 GO:0002070 epithelial cell maturation 1/138 15/18722 0.105075820705111 0.25318269179422 HIF1A 1 GO:0002730 regulation of dendritic cell cytokine production 1/138 15/18722 0.105075820705111 0.25318269179422 DDX21 1 GO:0010889 regulation of sequestering of triglyceride 1/138 15/18722 0.105075820705111 0.25318269179422 PLIN2 1 GO:0014048 regulation of glutamate secretion 1/138 15/18722 0.105075820705111 0.25318269179422 SNCA 1 GO:0021542 dentate gyrus development 1/138 15/18722 0.105075820705111 0.25318269179422 BTG2 1 GO:0030252 growth hormone secretion 1/138 15/18722 0.105075820705111 0.25318269179422 SERP1 1 GO:0030852 regulation of granulocyte differentiation 1/138 15/18722 0.105075820705111 0.25318269179422 TRIB1 1 GO:0032310 prostaglandin secretion 1/138 15/18722 0.105075820705111 0.25318269179422 IL1B 1 GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 1/138 15/18722 0.105075820705111 0.25318269179422 IL1B 1 GO:0032897 negative regulation of viral transcription 1/138 15/18722 0.105075820705111 0.25318269179422 ZFP36 1 GO:0033599 regulation of mammary gland epithelial cell proliferation 1/138 15/18722 0.105075820705111 0.25318269179422 GPX1 1 GO:0035493 SNARE complex assembly 1/138 15/18722 0.105075820705111 0.25318269179422 SNCA 1 GO:0042994 cytoplasmic sequestering of transcription factor 1/138 15/18722 0.105075820705111 0.25318269179422 NFKBIA 1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 1/138 15/18722 0.105075820705111 0.25318269179422 MIF 1 GO:0045475 locomotor rhythm 1/138 15/18722 0.105075820705111 0.25318269179422 EGR1 1 GO:0045725 positive regulation of glycogen biosynthetic process 1/138 15/18722 0.105075820705111 0.25318269179422 IRS2 1 GO:0045986 negative regulation of smooth muscle contraction 1/138 15/18722 0.105075820705111 0.25318269179422 PTGS2 1 GO:0046321 positive regulation of fatty acid oxidation 1/138 15/18722 0.105075820705111 0.25318269179422 IRS2 1 GO:0048308 organelle inheritance 1/138 15/18722 0.105075820705111 0.25318269179422 PLK3 1 GO:0048313 Golgi inheritance 1/138 15/18722 0.105075820705111 0.25318269179422 PLK3 1 GO:0070207 protein homotrimerization 1/138 15/18722 0.105075820705111 0.25318269179422 MIF 1 GO:0072224 metanephric glomerulus development 1/138 15/18722 0.105075820705111 0.25318269179422 EGR1 1 GO:0080154 regulation of fertilization 1/138 15/18722 0.105075820705111 0.25318269179422 MYH9 1 GO:0090594 inflammatory response to wounding 1/138 15/18722 0.105075820705111 0.25318269179422 HIF1A 1 GO:0110156 methylguanosine-cap decapping 1/138 15/18722 0.105075820705111 0.25318269179422 ZFP36 1 GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1/138 15/18722 0.105075820705111 0.25318269179422 ZFP36 1 GO:1901841 regulation of high voltage-gated calcium channel activity 1/138 15/18722 0.105075820705111 0.25318269179422 PDE4B 1 GO:1903729 regulation of plasma membrane organization 1/138 15/18722 0.105075820705111 0.25318269179422 MYH9 1 GO:0030856 regulation of epithelial cell differentiation 3/138 154/18722 0.105347363987199 0.253617399633542 ZFP36/CEBPB/IL1B 3 GO:0036465 synaptic vesicle recycling 2/138 75/18722 0.105804839599954 0.254059420713264 SNCA/ACTG1 2 GO:0043627 response to estrogen 2/138 75/18722 0.105804839599954 0.254059420713264 LDHA/KRT19 2 GO:1902369 negative regulation of RNA catabolic process 2/138 75/18722 0.105804839599954 0.254059420713264 ZFP36/YBX1 2 GO:0002443 leukocyte mediated immunity 6/138 440/18722 0.107181409437887 0.257142984884173 TREM1/HMGB1/DDX21/IL1B/CD55/BCL3 6 GO:0007015 actin filament organization 6/138 441/18722 0.108038283558137 0.258138512007938 PLEK/TPM3/ACTG1/GPR65/PHACTR1/RHOB 6 GO:0014823 response to activity 2/138 76/18722 0.108160908216517 0.258138512007938 CXCR4/HIF1A 2 GO:0140029 exocytic process 2/138 76/18722 0.108160908216517 0.258138512007938 PLEK/SNCA 2 GO:0001764 neuron migration 3/138 156/18722 0.108415341312578 0.258138512007938 DDIT4/CXCR4/PHACTR1 3 GO:0051960 regulation of nervous system development 6/138 443/18722 0.109762729186382 0.258138512007938 FN1/CXCR4/HIF1A/IL1B/SKIL/HMGB2 6 GO:0001837 epithelial to mesenchymal transition 3/138 157/18722 0.109962341330897 0.258138512007938 DDX5/HIF1A/IL1B 3 GO:1990845 adaptive thermogenesis 3/138 157/18722 0.109962341330897 0.258138512007938 G0S2/CEBPB/CXCR4 3 GO:0002200 somatic diversification of immune receptors 2/138 77/18722 0.110530977283724 0.258138512007938 HMGB1/HMGB2 2 GO:0006367 transcription initiation from RNA polymerase II promoter 2/138 77/18722 0.110530977283724 0.258138512007938 HMGB1/TAF10 2 GO:0010827 regulation of glucose transmembrane transport 2/138 77/18722 0.110530977283724 0.258138512007938 IL1B/IRS2 2 GO:1901983 regulation of protein acetylation 2/138 77/18722 0.110530977283724 0.258138512007938 SNCA/IL1B 2 GO:0030336 negative regulation of cell migration 5/138 344/18722 0.111024095542014 0.258138512007938 DUSP1/TRIB1/HMGB1/RHOB/MIF 5 GO:0018393 internal peptidyl-lysine acetylation 3/138 158/18722 0.111517908092147 0.258138512007938 SNCA/IL1B/TAF10 3 GO:0043488 regulation of mRNA stability 3/138 158/18722 0.111517908092147 0.258138512007938 BTG2/ZFP36/YBX1 3 GO:0002371 dendritic cell cytokine production 1/138 16/18722 0.111677602751548 0.258138512007938 DDX21 1 GO:0002713 negative regulation of B cell mediated immunity 1/138 16/18722 0.111677602751548 0.258138512007938 CD55 1 GO:0002827 positive regulation of T-helper 1 type immune response 1/138 16/18722 0.111677602751548 0.258138512007938 IL1B 1 GO:0002890 negative regulation of immunoglobulin mediated immune response 1/138 16/18722 0.111677602751548 0.258138512007938 CD55 1 GO:0002921 negative regulation of humoral immune response 1/138 16/18722 0.111677602751548 0.258138512007938 CD55 1 GO:0005980 glycogen catabolic process 1/138 16/18722 0.111677602751548 0.258138512007938 HMGB1 1 GO:0006266 DNA ligation 1/138 16/18722 0.111677602751548 0.258138512007938 HMGB1 1 GO:0009299 mRNA transcription 1/138 16/18722 0.111677602751548 0.258138512007938 DDX5 1 GO:0034116 positive regulation of heterotypic cell-cell adhesion 1/138 16/18722 0.111677602751548 0.258138512007938 IL1B 1 GO:0035067 negative regulation of histone acetylation 1/138 16/18722 0.111677602751548 0.258138512007938 SNCA 1 GO:0035970 peptidyl-threonine dephosphorylation 1/138 16/18722 0.111677602751548 0.258138512007938 DUSP1 1 GO:0043923 positive regulation by host of viral transcription 1/138 16/18722 0.111677602751548 0.258138512007938 JUN 1 GO:0044849 estrous cycle 1/138 16/18722 0.111677602751548 0.258138512007938 EGR1 1 GO:0045651 positive regulation of macrophage differentiation 1/138 16/18722 0.111677602751548 0.258138512007938 TRIB1 1 GO:0048385 regulation of retinoic acid receptor signaling pathway 1/138 16/18722 0.111677602751548 0.258138512007938 KLF2 1 GO:0050965 detection of temperature stimulus involved in sensory perception of pain 1/138 16/18722 0.111677602751548 0.258138512007938 CXCR4 1 GO:0051014 actin filament severing 1/138 16/18722 0.111677602751548 0.258138512007938 MYH9 1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis 1/138 16/18722 0.111677602751548 0.258138512007938 IL1B 1 GO:0051238 sequestering of metal ion 1/138 16/18722 0.111677602751548 0.258138512007938 FTH1 1 GO:0070242 thymocyte apoptotic process 1/138 16/18722 0.111677602751548 0.258138512007938 HIF1A 1 GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 1/138 16/18722 0.111677602751548 0.258138512007938 NFKBIA 1 GO:0072109 glomerular mesangium development 1/138 16/18722 0.111677602751548 0.258138512007938 EGR1 1 GO:0090231 regulation of spindle checkpoint 1/138 16/18722 0.111677602751548 0.258138512007938 DUSP1 1 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint 1/138 16/18722 0.111677602751548 0.258138512007938 DUSP1 1 GO:0090336 positive regulation of brown fat cell differentiation 1/138 16/18722 0.111677602751548 0.258138512007938 PTGS2 1 GO:0097428 protein maturation by iron-sulfur cluster transfer 1/138 16/18722 0.111677602751548 0.258138512007938 GLRX5 1 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/138 16/18722 0.111677602751548 0.258138512007938 MIF 1 GO:1902931 negative regulation of alcohol biosynthetic process 1/138 16/18722 0.111677602751548 0.258138512007938 PLEK 1 GO:1903504 regulation of mitotic spindle checkpoint 1/138 16/18722 0.111677602751548 0.258138512007938 DUSP1 1 GO:2000001 regulation of DNA damage checkpoint 1/138 16/18722 0.111677602751548 0.258138512007938 PPP1R10 1 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 4/138 249/18722 0.112455352934825 0.259720537110057 RIOK3/DDX21/IL1B/REL 4 GO:0030500 regulation of bone mineralization 2/138 78/18722 0.112914716288184 0.260303636556715 SRGN/HIF1A 2 GO:0090049 regulation of cell migration involved in sprouting angiogenesis 2/138 78/18722 0.112914716288184 0.260303636556715 PTGS2/ANXA1 2 GO:0035966 response to topologically incorrect protein 3/138 159/18722 0.113081960688849 0.260303636556715 PPP1R15A/SERP1/PPP1R15B 3 GO:1903169 regulation of calcium ion transmembrane transport 3/138 159/18722 0.113081960688849 0.260303636556715 SNCA/C4orf3/PDE4B 3 GO:0006475 internal protein amino acid acetylation 3/138 160/18722 0.114654418001225 0.2632700043708 SNCA/IL1B/TAF10 3 GO:0043271 negative regulation of ion transport 3/138 160/18722 0.114654418001225 0.2632700043708 PTGS2/SNCA/C4orf3 3 GO:0090316 positive regulation of intracellular protein transport 3/138 160/18722 0.114654418001225 0.2632700043708 PTGS2/IL1B/PLK3 3 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 2/138 79/18722 0.115311798763501 0.263440327059892 FN1/OSM 2 GO:0050772 positive regulation of axonogenesis 2/138 79/18722 0.115311798763501 0.263440327059892 FN1/SKIL 2 GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 2/138 79/18722 0.115311798763501 0.263440327059892 CXCL8/CXCL1 2 GO:0010951 negative regulation of endopeptidase activity 4/138 252/18722 0.116110721041859 0.263440327059892 PTGS2/PLAUR/GPX1/SNCA 4 GO:0042742 defense response to bacterium 5/138 350/18722 0.11711492333678 0.263440327059892 CEBPB/PRG2/TREM1/BCL3/HMGB2 5 GO:0032204 regulation of telomere maintenance 2/138 80/18722 0.117721902249296 0.263440327059892 PPP1R10/HNRNPA2B1 2 GO:0071229 cellular response to acid chemical 2/138 80/18722 0.117721902249296 0.263440327059892 CEBPB/KLF2 2 GO:0034250 positive regulation of cellular amide metabolic process 3/138 162/18722 0.117824221316436 0.263440327059892 PPP1R15A/SERP1/BCL3 3 GO:0051100 negative regulation of binding 3/138 162/18722 0.117824221316436 0.263440327059892 NFKBIA/C4orf3/JUN 3 GO:0060759 regulation of response to cytokine stimulus 3/138 162/18722 0.117824221316436 0.263440327059892 CXCR4/HIF1A/IL1R2 3 GO:0001829 trophectodermal cell differentiation 1/138 17/18722 0.118231034314698 0.263440327059892 JUNB 1 GO:0009251 glucan catabolic process 1/138 17/18722 0.118231034314698 0.263440327059892 HMGB1 1 GO:0010224 response to UV-B 1/138 17/18722 0.118231034314698 0.263440327059892 HMGN1 1 GO:0010566 regulation of ketone biosynthetic process 1/138 17/18722 0.118231034314698 0.263440327059892 EGR1 1 GO:0016264 gap junction assembly 1/138 17/18722 0.118231034314698 0.263440327059892 IL1B 1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway 1/138 17/18722 0.118231034314698 0.263440327059892 CHMP5 1 GO:0032604 granulocyte macrophage colony-stimulating factor production 1/138 17/18722 0.118231034314698 0.263440327059892 IL1B 1 GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 1/138 17/18722 0.118231034314698 0.263440327059892 IL1B 1 GO:0033623 regulation of integrin activation 1/138 17/18722 0.118231034314698 0.263440327059892 PLEK 1 GO:0036035 osteoclast development 1/138 17/18722 0.118231034314698 0.263440327059892 FBN1 1 GO:0042053 regulation of dopamine metabolic process 1/138 17/18722 0.118231034314698 0.263440327059892 SNCA 1 GO:0042069 regulation of catecholamine metabolic process 1/138 17/18722 0.118231034314698 0.263440327059892 SNCA 1 GO:0042448 progesterone metabolic process 1/138 17/18722 0.118231034314698 0.263440327059892 EGR1 1 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 1/138 17/18722 0.118231034314698 0.263440327059892 SOCS3 1 GO:0044539 long-chain fatty acid import into cell 1/138 17/18722 0.118231034314698 0.263440327059892 IRS2 1 GO:0046827 positive regulation of protein export from nucleus 1/138 17/18722 0.118231034314698 0.263440327059892 IL1B 1 GO:0051580 regulation of neurotransmitter uptake 1/138 17/18722 0.118231034314698 0.263440327059892 SNCA 1 GO:0055119 relaxation of cardiac muscle 1/138 17/18722 0.118231034314698 0.263440327059892 PDE4B 1 GO:0061158 3'-UTR-mediated mRNA destabilization 1/138 17/18722 0.118231034314698 0.263440327059892 ZFP36 1 GO:0061298 retina vasculature development in camera-type eye 1/138 17/18722 0.118231034314698 0.263440327059892 HIF1A 1 GO:0061952 midbody abscission 1/138 17/18722 0.118231034314698 0.263440327059892 CHMP5 1 GO:0070206 protein trimerization 1/138 17/18722 0.118231034314698 0.263440327059892 MIF 1 GO:0090494 dopamine uptake 1/138 17/18722 0.118231034314698 0.263440327059892 SNCA 1 GO:0140354 lipid import into cell 1/138 17/18722 0.118231034314698 0.263440327059892 IRS2 1 GO:1901550 regulation of endothelial cell development 1/138 17/18722 0.118231034314698 0.263440327059892 IL1B 1 GO:1903140 regulation of establishment of endothelial barrier 1/138 17/18722 0.118231034314698 0.263440327059892 IL1B 1 GO:2000811 negative regulation of anoikis 1/138 17/18722 0.118231034314698 0.263440327059892 MCL1 1 GO:0014032 neural crest cell development 2/138 81/18722 0.120144708250616 0.266377527608357 FN1/HIF1A 2 GO:0021954 central nervous system neuron development 2/138 81/18722 0.120144708250616 0.266377527608357 BTG2/UBB 2 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 2/138 81/18722 0.120144708250616 0.266377527608357 FBN1/SKIL 2 GO:0044773 mitotic DNA damage checkpoint signaling 2/138 81/18722 0.120144708250616 0.266377527608357 PPP1R10/PLK3 2 GO:0060968 regulation of gene silencing 2/138 81/18722 0.120144708250616 0.266377527608357 ZFP36/DDX5 2 GO:2001021 negative regulation of response to DNA damage stimulus 2/138 81/18722 0.120144708250616 0.266377527608357 PPP1R10/MIF 2 GO:0051480 regulation of cytosolic calcium ion concentration 5/138 353/18722 0.120219250692093 0.266377527608357 SNCA/HMGB1/CXCR4/GPR65/CD55 5 GO:0002700 regulation of production of molecular mediator of immune response 3/138 164/18722 0.12102666536141 0.267953229674466 DDX21/IL1B/CD55 3 GO:0007346 regulation of mitotic cell cycle 6/138 457/18722 0.122227926175732 0.26827016035182 DUSP1/BTG2/PPP1R10/IL1B/ANXA1/PLK3 6 GO:0060395 SMAD protein signal transduction 2/138 82/18722 0.1225799021977 0.26827016035182 FOS/JUN 2 GO:1905897 regulation of response to endoplasmic reticulum stress 2/138 82/18722 0.1225799021977 0.26827016035182 PPP1R15A/PPP1R15B 2 GO:2001252 positive regulation of chromosome organization 2/138 82/18722 0.1225799021977 0.26827016035182 PPP1R10/HNRNPA2B1 2 GO:0031348 negative regulation of defense response 4/138 258/18722 0.123576126124018 0.26827016035182 ZFP36/GPX1/RIOK3/SOCS3 4 GO:0043112 receptor metabolic process 3/138 166/18722 0.124261094937411 0.26827016035182 CXCL8/SNCA/CHMP5 3 GO:0061013 regulation of mRNA catabolic process 3/138 166/18722 0.124261094937411 0.26827016035182 BTG2/ZFP36/YBX1 3 GO:0001956 positive regulation of neurotransmitter secretion 1/138 18/18722 0.124736466940444 0.26827016035182 SNCA 1 GO:0002076 osteoblast development 1/138 18/18722 0.124736466940444 0.26827016035182 JUND 1 GO:0002643 regulation of tolerance induction 1/138 18/18722 0.124736466940444 0.26827016035182 HMGB1 1 GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 1/138 18/18722 0.124736466940444 0.26827016035182 CD55 1 GO:0015732 prostaglandin transport 1/138 18/18722 0.124736466940444 0.26827016035182 IL1B 1 GO:0019896 axonal transport of mitochondrion 1/138 18/18722 0.124736466940444 0.26827016035182 HIF1A 1 GO:0030728 ovulation 1/138 18/18722 0.124736466940444 0.26827016035182 PTGS2 1 GO:0032305 positive regulation of icosanoid secretion 1/138 18/18722 0.124736466940444 0.26827016035182 IL1B 1 GO:0032769 negative regulation of monooxygenase activity 1/138 18/18722 0.124736466940444 0.26827016035182 SNCA 1 GO:0034134 toll-like receptor 2 signaling pathway 1/138 18/18722 0.124736466940444 0.26827016035182 HMGB1 1 GO:0034162 toll-like receptor 9 signaling pathway 1/138 18/18722 0.124736466940444 0.26827016035182 HMGB1 1 GO:0035743 CD4-positive, alpha-beta T cell cytokine production 1/138 18/18722 0.124736466940444 0.26827016035182 IL1B 1 GO:0043217 myelin maintenance 1/138 18/18722 0.124736466940444 0.26827016035182 CXCR4 1 GO:0044247 cellular polysaccharide catabolic process 1/138 18/18722 0.124736466940444 0.26827016035182 HMGB1 1 GO:0045116 protein neddylation 1/138 18/18722 0.124736466940444 0.26827016035182 HIF1A 1 GO:0045623 negative regulation of T-helper cell differentiation 1/138 18/18722 0.124736466940444 0.26827016035182 ANXA1 1 GO:0051447 negative regulation of meiotic cell cycle 1/138 18/18722 0.124736466940444 0.26827016035182 DUSP1 1 GO:0060192 negative regulation of lipase activity 1/138 18/18722 0.124736466940444 0.26827016035182 ANXA1 1 GO:0060716 labyrinthine layer blood vessel development 1/138 18/18722 0.124736466940444 0.26827016035182 JUNB 1 GO:0060749 mammary gland alveolus development 1/138 18/18722 0.124736466940444 0.26827016035182 HIF1A 1 GO:0061377 mammary gland lobule development 1/138 18/18722 0.124736466940444 0.26827016035182 HIF1A 1 GO:0071318 cellular response to ATP 1/138 18/18722 0.124736466940444 0.26827016035182 PTGS2 1 GO:0090493 catecholamine uptake 1/138 18/18722 0.124736466940444 0.26827016035182 SNCA 1 GO:0097709 connective tissue replacement 1/138 18/18722 0.124736466940444 0.26827016035182 HIF1A 1 GO:0110154 RNA decapping 1/138 18/18722 0.124736466940444 0.26827016035182 ZFP36 1 GO:0150078 positive regulation of neuroinflammatory response 1/138 18/18722 0.124736466940444 0.26827016035182 IL1B 1 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1/138 18/18722 0.124736466940444 0.26827016035182 ZFP36 1 GO:1901673 regulation of mitotic spindle assembly 1/138 18/18722 0.124736466940444 0.26827016035182 CHMP5 1 GO:1902001 fatty acid transmembrane transport 1/138 18/18722 0.124736466940444 0.26827016035182 IRS2 1 GO:1903209 positive regulation of oxidative stress-induced cell death 1/138 18/18722 0.124736466940444 0.26827016035182 MCL1 1 GO:0007254 JNK cascade 3/138 167/18722 0.125890098962885 0.270542197230663 TRIB1/HMGB1/IL1B 3 GO:0071900 regulation of protein serine/threonine kinase activity 5/138 359/18722 0.126543542296684 0.271527122753795 DUSP1/TRIB1/CCNL1/SNCA/IL1B 5 GO:2000146 negative regulation of cell motility 5/138 359/18722 0.126543542296684 0.271527122753795 DUSP1/TRIB1/HMGB1/RHOB/MIF 5 GO:0006112 energy reserve metabolic process 2/138 84/18722 0.127486215037358 0.272377000133058 HMGB1/IRS2 2 GO:0006970 response to osmotic stress 2/138 84/18722 0.127486215037358 0.272377000133058 PTGS2/PLK3 2 GO:0032370 positive regulation of lipid transport 2/138 84/18722 0.127486215037358 0.272377000133058 NFKBIA/IL1B 2 GO:0061157 mRNA destabilization 2/138 84/18722 0.127486215037358 0.272377000133058 BTG2/ZFP36 2 GO:0098586 cellular response to virus 2/138 84/18722 0.127486215037358 0.272377000133058 RIOK3/HIF1A 2 GO:0002706 regulation of lymphocyte mediated immunity 3/138 168/18722 0.127526852739265 0.272377000133058 HMGB1/IL1B/CD55 3 GO:0010466 negative regulation of peptidase activity 4/138 262/18722 0.128664785674293 0.272775203735979 PTGS2/PLAUR/GPX1/SNCA 4 GO:0000075 cell cycle checkpoint signaling 3/138 169/18722 0.129171273840161 0.272775203735979 DUSP1/PPP1R10/PLK3 3 GO:0018394 peptidyl-lysine acetylation 3/138 169/18722 0.129171273840161 0.272775203735979 SNCA/IL1B/TAF10 3 GO:0003018 vascular process in circulatory system 4/138 263/18722 0.129950607877485 0.272775203735979 PTGS2/KLF2/GPX1/SLC2A3 4 GO:0001656 metanephros development 2/138 85/18722 0.129956724059551 0.272775203735979 EGR1/FBN1 2 GO:0010507 negative regulation of autophagy 2/138 85/18722 0.129956724059551 0.272775203735979 SNCA/MCL1 2 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 2/138 85/18722 0.129956724059551 0.272775203735979 OSM/SOCS3 2 GO:0044774 mitotic DNA integrity checkpoint signaling 2/138 85/18722 0.129956724059551 0.272775203735979 PPP1R10/PLK3 2 GO:0045069 regulation of viral genome replication 2/138 85/18722 0.129956724059551 0.272775203735979 CXCL8/DDX5 2 GO:0072384 organelle transport along microtubule 2/138 85/18722 0.129956724059551 0.272775203735979 HIF1A/UBB 2 GO:0007259 receptor signaling pathway via JAK-STAT 3/138 170/18722 0.130823279756965 0.272775203735979 OSM/SOCS3/BCL3 3 GO:0043487 regulation of RNA stability 3/138 170/18722 0.130823279756965 0.272775203735979 BTG2/ZFP36/YBX1 3 GO:0001696 gastric acid secretion 1/138 19/18722 0.131194249637312 0.272775203735979 SGK1 1 GO:0002281 macrophage activation involved in immune response 1/138 19/18722 0.131194249637312 0.272775203735979 HMGB1 1 GO:0002888 positive regulation of myeloid leukocyte mediated immunity 1/138 19/18722 0.131194249637312 0.272775203735979 DDX21 1 GO:0002902 regulation of B cell apoptotic process 1/138 19/18722 0.131194249637312 0.272775203735979 IRS2 1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 1/138 19/18722 0.131194249637312 0.272775203735979 PLK3 1 GO:0010738 regulation of protein kinase A signaling 1/138 19/18722 0.131194249637312 0.272775203735979 MIF 1 GO:0010829 negative regulation of glucose transmembrane transport 1/138 19/18722 0.131194249637312 0.272775203735979 IL1B 1 GO:0016082 synaptic vesicle priming 1/138 19/18722 0.131194249637312 0.272775203735979 SNCA 1 GO:0030220 platelet formation 1/138 19/18722 0.131194249637312 0.272775203735979 MYH9 1 GO:0032026 response to magnesium ion 1/138 19/18722 0.131194249637312 0.272775203735979 SNCA 1 GO:0033194 response to hydroperoxide 1/138 19/18722 0.131194249637312 0.272775203735979 GPX1 1 GO:0036344 platelet morphogenesis 1/138 19/18722 0.131194249637312 0.272775203735979 MYH9 1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate 1/138 19/18722 0.131194249637312 0.272775203735979 CXCL8 1 GO:0045821 positive regulation of glycolytic process 1/138 19/18722 0.131194249637312 0.272775203735979 HIF1A 1 GO:0046716 muscle cell cellular homeostasis 1/138 19/18722 0.131194249637312 0.272775203735979 HIF1A 1 GO:0046782 regulation of viral transcription 1/138 19/18722 0.131194249637312 0.272775203735979 ZFP36 1 GO:0050961 detection of temperature stimulus involved in sensory perception 1/138 19/18722 0.131194249637312 0.272775203735979 CXCR4 1 GO:0070233 negative regulation of T cell apoptotic process 1/138 19/18722 0.131194249637312 0.272775203735979 HIF1A 1 GO:0070989 oxidative demethylation 1/138 19/18722 0.131194249637312 0.272775203735979 JMJD6 1 GO:1901881 positive regulation of protein depolymerization 1/138 19/18722 0.131194249637312 0.272775203735979 PLEK 1 GO:1903204 negative regulation of oxidative stress-induced neuron death 1/138 19/18722 0.131194249637312 0.272775203735979 HIF1A 1 GO:2000269 regulation of fibroblast apoptotic process 1/138 19/18722 0.131194249637312 0.272775203735979 STK17B 1 GO:2000319 regulation of T-helper 17 cell differentiation 1/138 19/18722 0.131194249637312 0.272775203735979 NFKBIZ 1 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 4/138 264/18722 0.131241824578683 0.272775203735979 OSM/SAMSN1/SOCS3/MIF 4 GO:0014031 mesenchymal cell development 2/138 86/18722 0.132438401208862 0.274241167744448 FN1/HIF1A 2 GO:0048864 stem cell development 2/138 86/18722 0.132438401208862 0.274241167744448 FN1/HIF1A 2 GO:0048469 cell maturation 3/138 171/18722 0.132482787910643 0.274241167744448 KLF2/HIF1A/FAM210B 3 GO:0030522 intracellular receptor signaling pathway 4/138 265/18722 0.132538401227554 0.274241167744448 NFKBIA/KLF2/DDX5/RIOK3 4 GO:0051607 defense response to virus 4/138 265/18722 0.132538401227554 0.274241167744448 BNIP3L/DDIT4/RIOK3/DDX21 4 GO:0140546 defense response to symbiont 4/138 265/18722 0.132538401227554 0.274241167744448 BNIP3L/DDIT4/RIOK3/DDX21 4 GO:0002221 pattern recognition receptor signaling pathway 3/138 172/18722 0.134149715663319 0.277368988626313 NFKBIA/HMGB1/RIOK3 3 GO:0019646 aerobic electron transport chain 2/138 87/18722 0.134930950951016 0.278107451353535 SNCA/UQCRH 2 GO:0061014 positive regulation of mRNA catabolic process 2/138 87/18722 0.134930950951016 0.278107451353535 BTG2/ZFP36 2 GO:1901879 regulation of protein depolymerization 2/138 87/18722 0.134930950951016 0.278107451353535 PLEK/MID1IP1 2 GO:2000177 regulation of neural precursor cell proliferation 2/138 87/18722 0.134930950951016 0.278107451353535 BTG2/HIF1A 2 GO:0051271 negative regulation of cellular component movement 5/138 367/18722 0.135210339356971 0.278107451353535 DUSP1/TRIB1/HMGB1/RHOB/MIF 5 GO:0051099 positive regulation of binding 3/138 173/18722 0.135823980329649 0.278107451353535 PLAUR/HMGB1/HMGB2 3 GO:0009150 purine ribonucleotide metabolic process 5/138 368/18722 0.136312125385153 0.278107451353535 DDIT4/LDHA/SNCA/HIF1A/PDE4B 5 GO:0007260 tyrosine phosphorylation of STAT protein 2/138 88/18722 0.137434081443255 0.278107451353535 OSM/SOCS3 2 GO:0031110 regulation of microtubule polymerization or depolymerization 2/138 88/18722 0.137434081443255 0.278107451353535 SNCA/MID1IP1 2 GO:0050779 RNA destabilization 2/138 88/18722 0.137434081443255 0.278107451353535 BTG2/ZFP36 2 GO:0050829 defense response to Gram-negative bacterium 2/138 88/18722 0.137434081443255 0.278107451353535 TREM1/HMGB2 2 GO:0007584 response to nutrient 3/138 174/18722 0.137505499187992 0.278107451353535 PTGS2/LDHA/SRSF2 3 GO:0048639 positive regulation of developmental growth 3/138 174/18722 0.137505499187992 0.278107451353535 FN1/SERP1/CXCR4 3 GO:0000272 polysaccharide catabolic process 1/138 20/18722 0.137604728894652 0.278107451353535 HMGB1 1 GO:0002834 regulation of response to tumor cell 1/138 20/18722 0.137604728894652 0.278107451353535 HMGB1 1 GO:0002837 regulation of immune response to tumor cell 1/138 20/18722 0.137604728894652 0.278107451353535 HMGB1 1 GO:0006700 C21-steroid hormone biosynthetic process 1/138 20/18722 0.137604728894652 0.278107451353535 EGR1 1 GO:0006837 serotonin transport 1/138 20/18722 0.137604728894652 0.278107451353535 SNCA 1 GO:0009713 catechol-containing compound biosynthetic process 1/138 20/18722 0.137604728894652 0.278107451353535 SNCA 1 GO:0010042 response to manganese ion 1/138 20/18722 0.137604728894652 0.278107451353535 PTGS2 1 GO:0010801 negative regulation of peptidyl-threonine phosphorylation 1/138 20/18722 0.137604728894652 0.278107451353535 DDIT4 1 GO:0014047 glutamate secretion 1/138 20/18722 0.137604728894652 0.278107451353535 SNCA 1 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate 1/138 20/18722 0.137604728894652 0.278107451353535 CXCL8 1 GO:0042423 catecholamine biosynthetic process 1/138 20/18722 0.137604728894652 0.278107451353535 SNCA 1 GO:0046629 gamma-delta T cell activation 1/138 20/18722 0.137604728894652 0.278107451353535 EGR3 1 GO:0048025 negative regulation of mRNA splicing, via spliceosome 1/138 20/18722 0.137604728894652 0.278107451353535 SAP18 1 GO:0060252 positive regulation of glial cell proliferation 1/138 20/18722 0.137604728894652 0.278107451353535 IL1B 1 GO:0072567 chemokine (C-X-C motif) ligand 2 production 1/138 20/18722 0.137604728894652 0.278107451353535 HMGB1 1 GO:0090201 negative regulation of release of cytochrome c from mitochondria 1/138 20/18722 0.137604728894652 0.278107451353535 GPX1 1 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production 1/138 20/18722 0.137604728894652 0.278107451353535 HMGB1 1 GO:2000757 negative regulation of peptidyl-lysine acetylation 1/138 20/18722 0.137604728894652 0.278107451353535 SNCA 1 GO:0052126 movement in host environment 3/138 175/18722 0.139194189491381 0.281115696193406 CXCL8/CXCR4/CD55 3 GO:0046330 positive regulation of JNK cascade 2/138 89/18722 0.139947504496652 0.282432128364165 HMGB1/IL1B 2 GO:0050728 negative regulation of inflammatory response 3/138 176/18722 0.140889968478291 0.284128103097888 ZFP36/GPX1/SOCS3 3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 2/138 90/18722 0.142470935538757 0.286188311524303 TRIB1/PLK3 2 GO:0035304 regulation of protein dephosphorylation 2/138 90/18722 0.142470935538757 0.286188311524303 PPP1R15A/PPP1R15B 2 GO:0030324 lung development 3/138 177/18722 0.142592753383216 0.286188311524303 KLF2/HMGB1/JMJD6 3 GO:0043405 regulation of MAP kinase activity 3/138 177/18722 0.142592753383216 0.286188311524303 DUSP1/TRIB1/IL1B 3 GO:0006925 inflammatory cell apoptotic process 1/138 21/18722 0.143968248700691 0.286188311524303 ANXA1 1 GO:0007289 spermatid nucleus differentiation 1/138 21/18722 0.143968248700691 0.286188311524303 HMGB2 1 GO:0031145 anaphase-promoting complex-dependent catabolic process 1/138 21/18722 0.143968248700691 0.286188311524303 UBE2S 1 GO:0031998 regulation of fatty acid beta-oxidation 1/138 21/18722 0.143968248700691 0.286188311524303 IRS2 1 GO:0032303 regulation of icosanoid secretion 1/138 21/18722 0.143968248700691 0.286188311524303 IL1B 1 GO:0045655 regulation of monocyte differentiation 1/138 21/18722 0.143968248700691 0.286188311524303 JUN 1 GO:0046641 positive regulation of alpha-beta T cell proliferation 1/138 21/18722 0.143968248700691 0.286188311524303 CD55 1 GO:0048714 positive regulation of oligodendrocyte differentiation 1/138 21/18722 0.143968248700691 0.286188311524303 CXCR4 1 GO:0050849 negative regulation of calcium-mediated signaling 1/138 21/18722 0.143968248700691 0.286188311524303 PLEK 1 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 1/138 21/18722 0.143968248700691 0.286188311524303 DDX21 1 GO:0072111 cell proliferation involved in kidney development 1/138 21/18722 0.143968248700691 0.286188311524303 EGR1 1 GO:0090026 positive regulation of monocyte chemotaxis 1/138 21/18722 0.143968248700691 0.286188311524303 HMGB1 1 GO:0150105 protein localization to cell-cell junction 1/138 21/18722 0.143968248700691 0.286188311524303 ACTG1 1 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1/138 21/18722 0.143968248700691 0.286188311524303 MIF 1 GO:2000178 negative regulation of neural precursor cell proliferation 1/138 21/18722 0.143968248700691 0.286188311524303 BTG2 1 GO:2001014 regulation of skeletal muscle cell differentiation 1/138 21/18722 0.143968248700691 0.286188311524303 DDX5 1 GO:0002253 activation of immune response 5/138 375/18722 0.144136574487157 0.286318405994118 NFKBIZ/HMGB1/IL1B/CD55/PDE4B 5 GO:0002065 columnar/cuboidal epithelial cell differentiation 2/138 91/18722 0.145004093576595 0.287221631618267 CEBPB/HIF1A 2 GO:0014033 neural crest cell differentiation 2/138 91/18722 0.145004093576595 0.287221631618267 FN1/HIF1A 2 GO:0051492 regulation of stress fiber assembly 2/138 91/18722 0.145004093576595 0.287221631618267 ACTG1/GPR65 2 GO:0060191 regulation of lipase activity 2/138 91/18722 0.145004093576595 0.287221631618267 SNCA/ANXA1 2 GO:0018205 peptidyl-lysine modification 5/138 376/18722 0.145270116218446 0.287543907137934 EGR1/SNCA/IL1B/TAF10/JMJD6 5 GO:0002366 leukocyte activation involved in immune response 4/138 275/18722 0.145791236640667 0.288370299624007 NFKBIZ/HMGB1/ANXA1/BCL3 4 GO:0048660 regulation of smooth muscle cell proliferation 3/138 180/18722 0.14774231610787 0.291053287411083 PTGS2/TRIB1/JUN 3 GO:0006479 protein methylation 3/138 181/18722 0.149472297309378 0.291053287411083 BTG2/ETF1/GSPT1 3 GO:0008213 protein alkylation 3/138 181/18722 0.149472297309378 0.291053287411083 BTG2/ETF1/GSPT1 3 GO:0030323 respiratory tube development 3/138 181/18722 0.149472297309378 0.291053287411083 KLF2/HMGB1/JMJD6 3 GO:0097696 receptor signaling pathway via STAT 3/138 181/18722 0.149472297309378 0.291053287411083 OSM/SOCS3/BCL3 3 GO:0032088 negative regulation of NF-kappaB transcription factor activity 2/138 93/18722 0.15009848434534 0.291053287411083 NFKBIA/BCL3 2 GO:0033273 response to vitamin 2/138 93/18722 0.15009848434534 0.291053287411083 PTGS2/SRSF2 2 GO:1901019 regulation of calcium ion transmembrane transporter activity 2/138 93/18722 0.15009848434534 0.291053287411083 C4orf3/PDE4B 2 GO:0002053 positive regulation of mesenchymal cell proliferation 1/138 22/18722 0.150285150560448 0.291053287411083 IRS2 1 GO:0007398 ectoderm development 1/138 22/18722 0.150285150560448 0.291053287411083 ETS2 1 GO:0010310 regulation of hydrogen peroxide metabolic process 1/138 22/18722 0.150285150560448 0.291053287411083 SNCA 1 GO:0021854 hypothalamus development 1/138 22/18722 0.150285150560448 0.291053287411083 UBB 1 GO:0032727 positive regulation of interferon-alpha production 1/138 22/18722 0.150285150560448 0.291053287411083 HMGB1 1 GO:0032891 negative regulation of organic acid transport 1/138 22/18722 0.150285150560448 0.291053287411083 IRS2 1 GO:0044346 fibroblast apoptotic process 1/138 22/18722 0.150285150560448 0.291053287411083 STK17B 1 GO:0046058 cAMP metabolic process 1/138 22/18722 0.150285150560448 0.291053287411083 PDE4B 1 GO:0048026 positive regulation of mRNA splicing, via spliceosome 1/138 22/18722 0.150285150560448 0.291053287411083 PRDX6 1 GO:0048169 regulation of long-term neuronal synaptic plasticity 1/138 22/18722 0.150285150560448 0.291053287411083 SNCA 1 GO:0051220 cytoplasmic sequestering of protein 1/138 22/18722 0.150285150560448 0.291053287411083 NFKBIA 1 GO:0055093 response to hyperoxia 1/138 22/18722 0.150285150560448 0.291053287411083 FAS 1 GO:0060563 neuroepithelial cell differentiation 1/138 22/18722 0.150285150560448 0.291053287411083 CEBPB 1 GO:0060713 labyrinthine layer morphogenesis 1/138 22/18722 0.150285150560448 0.291053287411083 SOCS3 1 GO:0061042 vascular wound healing 1/138 22/18722 0.150285150560448 0.291053287411083 CXCR4 1 GO:0071359 cellular response to dsRNA 1/138 22/18722 0.150285150560448 0.291053287411083 RIOK3 1 GO:0072574 hepatocyte proliferation 1/138 22/18722 0.150285150560448 0.291053287411083 CEBPB 1 GO:0072575 epithelial cell proliferation involved in liver morphogenesis 1/138 22/18722 0.150285150560448 0.291053287411083 CEBPB 1 GO:1900543 negative regulation of purine nucleotide metabolic process 1/138 22/18722 0.150285150560448 0.291053287411083 DDIT4 1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus 1/138 22/18722 0.150285150560448 0.291053287411083 HIF1A 1 GO:2000193 positive regulation of fatty acid transport 1/138 22/18722 0.150285150560448 0.291053287411083 IL1B 1 GO:2000773 negative regulation of cellular senescence 1/138 22/18722 0.150285150560448 0.291053287411083 YBX1 1 GO:0002263 cell activation involved in immune response 4/138 279/18722 0.151233505325471 0.292686262392757 NFKBIZ/HMGB1/ANXA1/BCL3 4 GO:0002690 positive regulation of leukocyte chemotaxis 2/138 94/18722 0.152659172659438 0.295035053827233 CXCL8/HMGB1 2 GO:0019080 viral gene expression 2/138 94/18722 0.152659172659438 0.295035053827233 ZFP36/JUN 2 GO:0006644 phospholipid metabolic process 5/138 383/18722 0.153312509624783 0.295186123094957 PLEK/SNCA/SOCS3/IDI1/PRDX6 5 GO:0006470 protein dephosphorylation 4/138 281/18722 0.153983717417505 0.295186123094957 DUSP1/PTPRE/PPP1R15A/PPP1R15B 4 GO:0010498 proteasomal protein catabolic process 6/138 490/18722 0.15421586450992 0.295186123094957 TRIB1/GABARAPL2/GPX1/UBB/PLK3/UBE2S 6 GO:0014706 striated muscle tissue development 5/138 384/18722 0.154476553973134 0.295186123094957 FOS/EGR1/BTG2/GPX1/DDX5 5 GO:0042692 muscle cell differentiation 5/138 384/18722 0.154476553973134 0.295186123094957 GPX1/ACTG1/MYH9/YBX1/KRT19 5 GO:0048659 smooth muscle cell proliferation 3/138 184/18722 0.154701464990551 0.295186123094957 PTGS2/TRIB1/JUN 3 GO:0055001 muscle cell development 3/138 184/18722 0.154701464990551 0.295186123094957 GPX1/ACTG1/KRT19 3 GO:0002532 production of molecular mediator involved in inflammatory response 2/138 95/18722 0.15522849906402 0.295186123094957 HIF1A/IL1R2 2 GO:0008585 female gonad development 2/138 95/18722 0.15522849906402 0.295186123094957 CEBPB/UBB 2 GO:0042773 ATP synthesis coupled electron transport 2/138 95/18722 0.15522849906402 0.295186123094957 SNCA/UQCRH 2 GO:0042775 mitochondrial ATP synthesis coupled electron transport 2/138 95/18722 0.15522849906402 0.295186123094957 SNCA/UQCRH 2 GO:0050764 regulation of phagocytosis 2/138 95/18722 0.15522849906402 0.295186123094957 HMGB1/IL1B 2 GO:0009259 ribonucleotide metabolic process 5/138 385/18722 0.155644320088204 0.295186123094957 DDIT4/LDHA/SNCA/HIF1A/PDE4B 5 GO:0043433 negative regulation of DNA-binding transcription factor activity 3/138 185/18722 0.156457320541196 0.295186123094957 TRIB1/NFKBIA/BCL3 3 GO:0002052 positive regulation of neuroblast proliferation 1/138 23/18722 0.156555773513531 0.295186123094957 HIF1A 1 GO:0002082 regulation of oxidative phosphorylation 1/138 23/18722 0.156555773513531 0.295186123094957 SNCA 1 GO:0006929 substrate-dependent cell migration 1/138 23/18722 0.156555773513531 0.295186123094957 FN1 1 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 1/138 23/18722 0.156555773513531 0.295186123094957 SNCA 1 GO:0010888 negative regulation of lipid storage 1/138 23/18722 0.156555773513531 0.295186123094957 NFKBIA 1 GO:0016578 histone deubiquitination 1/138 23/18722 0.156555773513531 0.295186123094957 TAF10 1 GO:0021884 forebrain neuron development 1/138 23/18722 0.156555773513531 0.295186123094957 UBB 1 GO:0032740 positive regulation of interleukin-17 production 1/138 23/18722 0.156555773513531 0.295186123094957 OSM 1 GO:0033081 regulation of T cell differentiation in thymus 1/138 23/18722 0.156555773513531 0.295186123094957 EGR3 1 GO:0035162 embryonic hemopoiesis 1/138 23/18722 0.156555773513531 0.295186123094957 HIF1A 1 GO:0045932 negative regulation of muscle contraction 1/138 23/18722 0.156555773513531 0.295186123094957 PTGS2 1 GO:0045980 negative regulation of nucleotide metabolic process 1/138 23/18722 0.156555773513531 0.295186123094957 DDIT4 1 GO:0050765 negative regulation of phagocytosis 1/138 23/18722 0.156555773513531 0.295186123094957 HMGB1 1 GO:0051457 maintenance of protein location in nucleus 1/138 23/18722 0.156555773513531 0.295186123094957 MORC3 1 GO:0051590 positive regulation of neurotransmitter transport 1/138 23/18722 0.156555773513531 0.295186123094957 SNCA 1 GO:0060487 lung epithelial cell differentiation 1/138 23/18722 0.156555773513531 0.295186123094957 KLF2 1 GO:0060575 intestinal epithelial cell differentiation 1/138 23/18722 0.156555773513531 0.295186123094957 HIF1A 1 GO:0071636 positive regulation of transforming growth factor beta production 1/138 23/18722 0.156555773513531 0.295186123094957 PTGS2 1 GO:0072576 liver morphogenesis 1/138 23/18722 0.156555773513531 0.295186123094957 CEBPB 1 GO:0090335 regulation of brown fat cell differentiation 1/138 23/18722 0.156555773513531 0.295186123094957 PTGS2 1 GO:1902410 mitotic cytokinetic process 1/138 23/18722 0.156555773513531 0.295186123094957 CHMP5 1 GO:1904666 regulation of ubiquitin protein ligase activity 1/138 23/18722 0.156555773513531 0.295186123094957 UBE2S 1 GO:0030510 regulation of BMP signaling pathway 2/138 96/18722 0.157806199920348 0.296940266652014 FBN1/SKIL 2 GO:0044264 cellular polysaccharide metabolic process 2/138 96/18722 0.157806199920348 0.296940266652014 HMGB1/IRS2 2 GO:1901655 cellular response to ketone 2/138 96/18722 0.157806199920348 0.296940266652014 KLF2/DDIT4 2 GO:0008217 regulation of blood pressure 3/138 186/18722 0.158219438591596 0.297315798514795 PTGS2/HBB/SGK1 3 GO:0071478 cellular response to radiation 3/138 186/18722 0.158219438591596 0.297315798514795 EGR1/PTGS2/RHOB 3 GO:0033044 regulation of chromosome organization 3/138 187/18722 0.159987736876498 0.299813371214084 DUSP1/PPP1R10/HNRNPA2B1 3 GO:0035335 peptidyl-tyrosine dephosphorylation 2/138 97/18722 0.160392014954238 0.299813371214084 DUSP1/PTPRE 2 GO:0051656 establishment of organelle localization 5/138 390/18722 0.161538252697035 0.299813371214084 SNCA/MYH9/HIF1A/UBB/CHMP5 5 GO:0140014 mitotic nuclear division 4/138 287/18722 0.16234709935582 0.299813371214084 DUSP1/IL1B/CHMP5/UBE2S 4 GO:0040013 negative regulation of locomotion 5/138 391/18722 0.162727913318158 0.299813371214084 DUSP1/TRIB1/HMGB1/RHOB/MIF 5 GO:0001702 gastrulation with mouth forming second 1/138 24/18722 0.162780454151808 0.299813371214084 ETS2 1 GO:0001779 natural killer cell differentiation 1/138 24/18722 0.162780454151808 0.299813371214084 NFIL3 1 GO:0001783 B cell apoptotic process 1/138 24/18722 0.162780454151808 0.299813371214084 IRS2 1 GO:0002922 positive regulation of humoral immune response 1/138 24/18722 0.162780454151808 0.299813371214084 IL1B 1 GO:0006817 phosphate ion transport 1/138 24/18722 0.162780454151808 0.299813371214084 CEBPB 1 GO:0010226 response to lithium ion 1/138 24/18722 0.162780454151808 0.299813371214084 PTGS2 1 GO:0010288 response to lead ion 1/138 24/18722 0.162780454151808 0.299813371214084 PTGS2 1 GO:0016048 detection of temperature stimulus 1/138 24/18722 0.162780454151808 0.299813371214084 CXCR4 1 GO:0033032 regulation of myeloid cell apoptotic process 1/138 24/18722 0.162780454151808 0.299813371214084 ANXA1 1 GO:0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 1/138 24/18722 0.162780454151808 0.299813371214084 RIOK3 1 GO:0045649 regulation of macrophage differentiation 1/138 24/18722 0.162780454151808 0.299813371214084 TRIB1 1 GO:0048011 neurotrophin TRK receptor signaling pathway 1/138 24/18722 0.162780454151808 0.299813371214084 DDIT4 1 GO:0050687 negative regulation of defense response to virus 1/138 24/18722 0.162780454151808 0.299813371214084 RIOK3 1 GO:0051000 positive regulation of nitric-oxide synthase activity 1/138 24/18722 0.162780454151808 0.299813371214084 HIF1A 1 GO:0051043 regulation of membrane protein ectodomain proteolysis 1/138 24/18722 0.162780454151808 0.299813371214084 IL1B 1 GO:0051123 RNA polymerase II preinitiation complex assembly 1/138 24/18722 0.162780454151808 0.299813371214084 HMGB1 1 GO:0060479 lung cell differentiation 1/138 24/18722 0.162780454151808 0.299813371214084 KLF2 1 GO:0060571 morphogenesis of an epithelial fold 1/138 24/18722 0.162780454151808 0.299813371214084 HIF1A 1 GO:0070935 3'-UTR-mediated mRNA stabilization 1/138 24/18722 0.162780454151808 0.299813371214084 ZFP36 1 GO:0071676 negative regulation of mononuclear cell migration 1/138 24/18722 0.162780454151808 0.299813371214084 DUSP1 1 GO:0090023 positive regulation of neutrophil chemotaxis 1/138 24/18722 0.162780454151808 0.299813371214084 CXCL8 1 GO:0120255 olefinic compound biosynthetic process 1/138 24/18722 0.162780454151808 0.299813371214084 EGR1 1 GO:1901984 negative regulation of protein acetylation 1/138 24/18722 0.162780454151808 0.299813371214084 SNCA 1 GO:1903861 positive regulation of dendrite extension 1/138 24/18722 0.162780454151808 0.299813371214084 CXCR4 1 GO:2000209 regulation of anoikis 1/138 24/18722 0.162780454151808 0.299813371214084 MCL1 1 GO:0009060 aerobic respiration 3/138 189/18722 0.163542545597517 0.301017793913947 SNCA/HIF1A/UQCRH 3 GO:0002444 myeloid leukocyte mediated immunity 2/138 99/18722 0.165586963073064 0.304177239757318 TREM1/DDX21 2 GO:0033209 tumor necrosis factor-mediated signaling pathway 2/138 99/18722 0.165586963073064 0.304177239757318 NFKBIA/FAS 2 GO:0042100 B cell proliferation 2/138 99/18722 0.165586963073064 0.304177239757318 IRS2/MIF 2 GO:0071103 DNA conformation change 4/138 290/18722 0.166590350574935 0.304542980978375 HMGB1/ANXA1/HNRNPA2B1/HMGB2 4 GO:0060485 mesenchyme development 4/138 291/18722 0.168013635283921 0.304542980978375 FN1/DDX5/HIF1A/IL1B 4 GO:0046545 development of primary female sexual characteristics 2/138 100/18722 0.16819559212202 0.304542980978375 CEBPB/UBB 2 GO:0061640 cytoskeleton-dependent cytokinesis 2/138 100/18722 0.16819559212202 0.304542980978375 CHMP5/RHOB 2 GO:0110020 regulation of actomyosin structure organization 2/138 100/18722 0.16819559212202 0.304542980978375 ACTG1/GPR65 2 GO:0006163 purine nucleotide metabolic process 5/138 396/18722 0.168729421406824 0.304542980978375 DDIT4/LDHA/SNCA/HIF1A/PDE4B 5 GO:0019693 ribose phosphate metabolic process 5/138 396/18722 0.168729421406824 0.304542980978375 DDIT4/LDHA/SNCA/HIF1A/PDE4B 5 GO:0007274 neuromuscular synaptic transmission 1/138 25/18722 0.168959526636943 0.304542980978375 EGR3 1 GO:0010447 response to acidic pH 1/138 25/18722 0.168959526636943 0.304542980978375 GPR65 1 GO:0010954 positive regulation of protein processing 1/138 25/18722 0.168959526636943 0.304542980978375 MYH9 1 GO:0015874 norepinephrine transport 1/138 25/18722 0.168959526636943 0.304542980978375 SNCA 1 GO:0032753 positive regulation of interleukin-4 production 1/138 25/18722 0.168959526636943 0.304542980978375 CEBPB 1 GO:0033119 negative regulation of RNA splicing 1/138 25/18722 0.168959526636943 0.304542980978375 SAP18 1 GO:0033233 regulation of protein sumoylation 1/138 25/18722 0.168959526636943 0.304542980978375 EGR1 1 GO:0035902 response to immobilization stress 1/138 25/18722 0.168959526636943 0.304542980978375 FOS 1 GO:0042832 defense response to protozoan 1/138 25/18722 0.168959526636943 0.304542980978375 BCL3 1 GO:0045324 late endosome to vacuole transport 1/138 25/18722 0.168959526636943 0.304542980978375 CHMP5 1 GO:0050927 positive regulation of positive chemotaxis 1/138 25/18722 0.168959526636943 0.304542980978375 CXCL8 1 GO:0050951 sensory perception of temperature stimulus 1/138 25/18722 0.168959526636943 0.304542980978375 CXCR4 1 GO:0050995 negative regulation of lipid catabolic process 1/138 25/18722 0.168959526636943 0.304542980978375 IL1B 1 GO:0051450 myoblast proliferation 1/138 25/18722 0.168959526636943 0.304542980978375 GPX1 1 GO:0062149 detection of stimulus involved in sensory perception of pain 1/138 25/18722 0.168959526636943 0.304542980978375 CXCR4 1 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 1/138 25/18722 0.168959526636943 0.304542980978375 NFKBIA 1 GO:0072012 glomerulus vasculature development 1/138 25/18722 0.168959526636943 0.304542980978375 EGR1 1 GO:0090169 regulation of spindle assembly 1/138 25/18722 0.168959526636943 0.304542980978375 CHMP5 1 GO:1902932 positive regulation of alcohol biosynthetic process 1/138 25/18722 0.168959526636943 0.304542980978375 SNCA 1 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA 1/138 25/18722 0.168959526636943 0.304542980978375 DDX5 1 GO:1905564 positive regulation of vascular endothelial cell proliferation 1/138 25/18722 0.168959526636943 0.304542980978375 HMGB1 1 GO:2000316 regulation of T-helper 17 type immune response 1/138 25/18722 0.168959526636943 0.304542980978375 NFKBIZ 1 GO:0006869 lipid transport 5/138 398/18722 0.171154452477716 0.308299573621673 NFKBIA/IL1B/ANXA1/PLIN2/IRS2 5 GO:0051604 protein maturation 4/138 294/18722 0.172309558204826 0.310179495785273 SRGN/MYH9/GLRX5/IL1R2 4 GO:0062014 negative regulation of small molecule metabolic process 2/138 102/18722 0.173433924368546 0.311762454973566 PLEK/DDIT4 2 GO:0001562 response to protozoan 1/138 26/18722 0.175093322717816 0.311762454973566 BCL3 1 GO:0002418 immune response to tumor cell 1/138 26/18722 0.175093322717816 0.311762454973566 HMGB1 1 GO:0010875 positive regulation of cholesterol efflux 1/138 26/18722 0.175093322717816 0.311762454973566 NFKBIA 1 GO:0016226 iron-sulfur cluster assembly 1/138 26/18722 0.175093322717816 0.311762454973566 GLRX5 1 GO:0031163 metallo-sulfur cluster assembly 1/138 26/18722 0.175093322717816 0.311762454973566 GLRX5 1 GO:0032515 negative regulation of phosphoprotein phosphatase activity 1/138 26/18722 0.175093322717816 0.311762454973566 PPP1R15A 1 GO:0034114 regulation of heterotypic cell-cell adhesion 1/138 26/18722 0.175093322717816 0.311762454973566 IL1B 1 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 1/138 26/18722 0.175093322717816 0.311762454973566 NFKBIA 1 GO:0045672 positive regulation of osteoclast differentiation 1/138 26/18722 0.175093322717816 0.311762454973566 FOS 1 GO:0046755 viral budding 1/138 26/18722 0.175093322717816 0.311762454973566 CHMP5 1 GO:0050926 regulation of positive chemotaxis 1/138 26/18722 0.175093322717816 0.311762454973566 CXCL8 1 GO:0060669 embryonic placenta morphogenesis 1/138 26/18722 0.175093322717816 0.311762454973566 SOCS3 1 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA 1/138 26/18722 0.175093322717816 0.311762454973566 DDX5 1 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway 1/138 26/18722 0.175093322717816 0.311762454973566 PDE4B 1 GO:1900017 positive regulation of cytokine production involved in inflammatory response 1/138 26/18722 0.175093322717816 0.311762454973566 HIF1A 1 GO:2000108 positive regulation of leukocyte apoptotic process 1/138 26/18722 0.175093322717816 0.311762454973566 ANXA1 1 GO:0014013 regulation of gliogenesis 2/138 103/18722 0.176063142797463 0.312673980036307 CXCR4/IL1B 2 GO:0019233 sensory perception of pain 2/138 103/18722 0.176063142797463 0.312673980036307 PTGS2/CXCR4 2 GO:0032760 positive regulation of tumor necrosis factor production 2/138 103/18722 0.176063142797463 0.312673980036307 HMGB1/MIF 2 GO:0046425 regulation of receptor signaling pathway via JAK-STAT 2/138 103/18722 0.176063142797463 0.312673980036307 SOCS3/BCL3 2 GO:0022408 negative regulation of cell-cell adhesion 3/138 196/18722 0.176167014264078 0.312673980036307 CEBPB/HMGB1/ANXA1 3 GO:0060537 muscle tissue development 5/138 403/18722 0.177276575779372 0.31444277271765 FOS/EGR1/BTG2/GPX1/DDX5 5 GO:0031647 regulation of protein stability 4/138 298/18722 0.178096850353232 0.315696518810856 SNCA/RNF149/AHSP/MORC3 4 GO:0032006 regulation of TOR signaling 2/138 104/18722 0.178698744820502 0.316209649106937 DDIT4/HIF1A 2 GO:0048661 positive regulation of smooth muscle cell proliferation 2/138 104/18722 0.178698744820502 0.316209649106937 PTGS2/JUN 2 GO:0031099 regeneration 3/138 198/18722 0.179823502127818 0.316209649106937 CEBPB/GPX1/ANXA1 3 GO:0050864 regulation of B cell activation 3/138 198/18722 0.179823502127818 0.316209649106937 SAMSN1/IRS2/MIF 3 GO:0010959 regulation of metal ion transport 5/138 406/18722 0.18098979803939 0.316209649106937 PTGS2/SNCA/C4orf3/CXCR4/PDE4B 5 GO:0016050 vesicle organization 4/138 300/18722 0.181015257747399 0.316209649106937 SNCA/SRGN/ANXA1/CHMP5 4 GO:0006783 heme biosynthetic process 1/138 27/18722 0.18118217174782 0.316209649106937 ALAS2 1 GO:0007026 negative regulation of microtubule depolymerization 1/138 27/18722 0.18118217174782 0.316209649106937 MID1IP1 1 GO:0010758 regulation of macrophage chemotaxis 1/138 27/18722 0.18118217174782 0.316209649106937 MIF 1 GO:0014850 response to muscle activity 1/138 27/18722 0.18118217174782 0.316209649106937 HIF1A 1 GO:0018126 protein hydroxylation 1/138 27/18722 0.18118217174782 0.316209649106937 JMJD6 1 GO:0032703 negative regulation of interleukin-2 production 1/138 27/18722 0.18118217174782 0.316209649106937 ZFP36 1 GO:0032781 positive regulation of ATPase activity 1/138 27/18722 0.18118217174782 0.316209649106937 GABARAPL2 1 GO:0032786 positive regulation of DNA-templated transcription, elongation 1/138 27/18722 0.18118217174782 0.316209649106937 HMGN1 1 GO:0034143 regulation of toll-like receptor 4 signaling pathway 1/138 27/18722 0.18118217174782 0.316209649106937 HMGB1 1 GO:0042104 positive regulation of activated T cell proliferation 1/138 27/18722 0.18118217174782 0.316209649106937 HMGB1 1 GO:0042402 cellular biogenic amine catabolic process 1/138 27/18722 0.18118217174782 0.316209649106937 SAT1 1 GO:0051953 negative regulation of amine transport 1/138 27/18722 0.18118217174782 0.316209649106937 SNCA 1 GO:0061437 renal system vasculature development 1/138 27/18722 0.18118217174782 0.316209649106937 EGR1 1 GO:0061440 kidney vasculature development 1/138 27/18722 0.18118217174782 0.316209649106937 EGR1 1 GO:0071624 positive regulation of granulocyte chemotaxis 1/138 27/18722 0.18118217174782 0.316209649106937 CXCL8 1 GO:1903319 positive regulation of protein maturation 1/138 27/18722 0.18118217174782 0.316209649106937 MYH9 1 GO:1903421 regulation of synaptic vesicle recycling 1/138 27/18722 0.18118217174782 0.316209649106937 SNCA 1 GO:1903859 regulation of dendrite extension 1/138 27/18722 0.18118217174782 0.316209649106937 CXCR4 1 GO:0040029 regulation of gene expression, epigenetic 2/138 105/18722 0.181340495858667 0.316209649106937 KLF2/GPX1 2 GO:0062207 regulation of pattern recognition receptor signaling pathway 2/138 105/18722 0.181340495858667 0.316209649106937 HMGB1/RIOK3 2 GO:0045216 cell-cell junction organization 3/138 200/18722 0.183500802762139 0.319075978661192 TLN1/ACTG1/IL1B 3 GO:0001824 blastocyst development 2/138 106/18722 0.183988164396891 0.319075978661192 JUNB/SKIL 2 GO:0006906 vesicle fusion 2/138 106/18722 0.183988164396891 0.319075978661192 SNCA/ANXA1 2 GO:0046822 regulation of nucleocytoplasmic transport 2/138 106/18722 0.183988164396891 0.319075978661192 PTGS2/IL1B 2 GO:2000278 regulation of DNA biosynthetic process 2/138 106/18722 0.183988164396891 0.319075978661192 DUSP1/HNRNPA2B1 2 GO:0006473 protein acetylation 3/138 201/18722 0.185347057107559 0.319075978661192 SNCA/IL1B/TAF10 3 GO:0051054 positive regulation of DNA metabolic process 3/138 201/18722 0.185347057107559 0.319075978661192 HMGB1/PPP1R10/HNRNPA2B1 3 GO:0007162 negative regulation of cell adhesion 4/138 303/18722 0.185422949383825 0.319075978661192 DUSP1/CEBPB/HMGB1/ANXA1 4 GO:0005976 polysaccharide metabolic process 2/138 107/18722 0.186641521952171 0.319075978661192 HMGB1/IRS2 2 GO:0010927 cellular component assembly involved in morphogenesis 2/138 107/18722 0.186641521952171 0.319075978661192 ACTG1/KRT19 2 GO:0021761 limbic system development 2/138 107/18722 0.186641521952171 0.319075978661192 BTG2/UBB 2 GO:0071868 cellular response to monoamine stimulus 2/138 107/18722 0.186641521952171 0.319075978661192 SNCA/PDE4B 2 GO:0071870 cellular response to catecholamine stimulus 2/138 107/18722 0.186641521952171 0.319075978661192 SNCA/PDE4B 2 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 2/138 107/18722 0.186641521952171 0.319075978661192 HMGB1/MIF 2 GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 2/138 107/18722 0.186641521952171 0.319075978661192 TRIB1/PLK3 2 GO:0016051 carbohydrate biosynthetic process 3/138 202/18722 0.187198274131987 0.319075978661192 PLEK/SNCA/IRS2 3 GO:0019722 calcium-mediated signaling 3/138 202/18722 0.187198274131987 0.319075978661192 CXCL8/PLEK/CXCR4 3 GO:0032388 positive regulation of intracellular transport 3/138 202/18722 0.187198274131987 0.319075978661192 PTGS2/IL1B/PLK3 3 GO:0000470 maturation of LSU-rRNA 1/138 28/18722 0.187226400702022 0.319075978661192 RPL7 1 GO:0002313 mature B cell differentiation involved in immune response 1/138 28/18722 0.187226400702022 0.319075978661192 BCL3 1 GO:0002507 tolerance induction 1/138 28/18722 0.187226400702022 0.319075978661192 HMGB1 1 GO:0007141 male meiosis I 1/138 28/18722 0.187226400702022 0.319075978661192 UBB 1 GO:0008299 isoprenoid biosynthetic process 1/138 28/18722 0.187226400702022 0.319075978661192 IDI1 1 GO:0010464 regulation of mesenchymal cell proliferation 1/138 28/18722 0.187226400702022 0.319075978661192 IRS2 1 GO:0010884 positive regulation of lipid storage 1/138 28/18722 0.187226400702022 0.319075978661192 PLIN2 1 GO:0032607 interferon-alpha production 1/138 28/18722 0.187226400702022 0.319075978661192 HMGB1 1 GO:0032647 regulation of interferon-alpha production 1/138 28/18722 0.187226400702022 0.319075978661192 HMGB1 1 GO:0034123 positive regulation of toll-like receptor signaling pathway 1/138 28/18722 0.187226400702022 0.319075978661192 HMGB1 1 GO:0045671 negative regulation of osteoclast differentiation 1/138 28/18722 0.187226400702022 0.319075978661192 FBN1 1 GO:0060325 face morphogenesis 1/138 28/18722 0.187226400702022 0.319075978661192 CSRNP1 1 GO:0060765 regulation of androgen receptor signaling pathway 1/138 28/18722 0.187226400702022 0.319075978661192 DDX5 1 GO:0061082 myeloid leukocyte cytokine production 1/138 28/18722 0.187226400702022 0.319075978661192 DDX21 1 GO:0090200 positive regulation of release of cytochrome c from mitochondria 1/138 28/18722 0.187226400702022 0.319075978661192 PLAUR 1 GO:1902624 positive regulation of neutrophil migration 1/138 28/18722 0.187226400702022 0.319075978661192 CXCL8 1 GO:1903671 negative regulation of sprouting angiogenesis 1/138 28/18722 0.187226400702022 0.319075978661192 KLF2 1 GO:1903672 positive regulation of sprouting angiogenesis 1/138 28/18722 0.187226400702022 0.319075978661192 HMGB1 1 GO:1990776 response to angiotensin 1/138 28/18722 0.187226400702022 0.319075978661192 PTGS2 1 GO:0051701 biological process involved in interaction with host 3/138 203/18722 0.189054374091168 0.321797139508086 CXCL8/CXCR4/CD55 3 GO:0060541 respiratory system development 3/138 203/18722 0.189054374091168 0.321797139508086 KLF2/HMGB1/JMJD6 3 GO:0002832 negative regulation of response to biotic stimulus 2/138 108/18722 0.189300343042005 0.322018859832457 TRIB1/RIOK3 2 GO:1901888 regulation of cell junction assembly 3/138 204/18722 0.190915277456749 0.324531616211532 SNCA/ACTG1/IL1B 3 GO:0032410 negative regulation of transporter activity 2/138 109/18722 0.191964405153118 0.324531616211532 SNCA/C4orf3 2 GO:0002440 production of molecular mediator of immune response 4/138 308/18722 0.192846724441129 0.324531616211532 TREM1/DDX21/IL1B/CD55 4 GO:0001773 myeloid dendritic cell activation 1/138 29/18722 0.193226334194218 0.324531616211532 HMGB1 1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus 1/138 29/18722 0.193226334194218 0.324531616211532 GPX1 1 GO:0005979 regulation of glycogen biosynthetic process 1/138 29/18722 0.193226334194218 0.324531616211532 IRS2 1 GO:0007143 female meiotic nuclear division 1/138 29/18722 0.193226334194218 0.324531616211532 UBB 1 GO:0009310 amine catabolic process 1/138 29/18722 0.193226334194218 0.324531616211532 SAT1 1 GO:0010458 exit from mitosis 1/138 29/18722 0.193226334194218 0.324531616211532 UBE2S 1 GO:0010955 negative regulation of protein processing 1/138 29/18722 0.193226334194218 0.324531616211532 IL1R2 1 GO:0010962 regulation of glucan biosynthetic process 1/138 29/18722 0.193226334194218 0.324531616211532 IRS2 1 GO:0033028 myeloid cell apoptotic process 1/138 29/18722 0.193226334194218 0.324531616211532 ANXA1 1 GO:0035066 positive regulation of histone acetylation 1/138 29/18722 0.193226334194218 0.324531616211532 IL1B 1 GO:0050686 negative regulation of mRNA processing 1/138 29/18722 0.193226334194218 0.324531616211532 SAP18 1 GO:0051873 killing by host of symbiont cells 1/138 29/18722 0.193226334194218 0.324531616211532 TREM1 1 GO:0051883 killing of cells in other organism involved in symbiotic interaction 1/138 29/18722 0.193226334194218 0.324531616211532 TREM1 1 GO:0070979 protein K11-linked ubiquitination 1/138 29/18722 0.193226334194218 0.324531616211532 UBE2S 1 GO:0071549 cellular response to dexamethasone stimulus 1/138 29/18722 0.193226334194218 0.324531616211532 DDIT4 1 GO:0072539 T-helper 17 cell differentiation 1/138 29/18722 0.193226334194218 0.324531616211532 NFKBIZ 1 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 1/138 29/18722 0.193226334194218 0.324531616211532 MIF 1 GO:1903318 negative regulation of protein maturation 1/138 29/18722 0.193226334194218 0.324531616211532 IL1R2 1 GO:0072521 purine-containing compound metabolic process 5/138 416/18722 0.193574839999995 0.324920856284671 DDIT4/LDHA/SNCA/HIF1A/PDE4B 5 GO:0002698 negative regulation of immune effector process 2/138 110/18722 0.194633488710482 0.325158599477538 ANXA1/CD55 2 GO:0003014 renal system process 2/138 110/18722 0.194633488710482 0.325158599477538 HBB/SGK1 2 GO:0007088 regulation of mitotic nuclear division 2/138 110/18722 0.194633488710482 0.325158599477538 DUSP1/IL1B 2 GO:0014812 muscle cell migration 2/138 110/18722 0.194633488710482 0.325158599477538 TRIB1/ANXA1 2 GO:0032611 interleukin-1 beta production 2/138 110/18722 0.194633488710482 0.325158599477538 EGR1/HMGB1 2 GO:0032651 regulation of interleukin-1 beta production 2/138 110/18722 0.194633488710482 0.325158599477538 EGR1/HMGB1 2 GO:0090174 organelle membrane fusion 2/138 110/18722 0.194633488710482 0.325158599477538 SNCA/ANXA1 2 GO:0048863 stem cell differentiation 3/138 206/18722 0.194651177409119 0.325158599477538 FN1/OSM/HIF1A 3 GO:0016311 dephosphorylation 5/138 417/18722 0.194850329142487 0.325296020398045 DUSP1/PTPRE/PPP1R15A/PLEK/PPP1R15B 5 GO:0032409 regulation of transporter activity 4/138 310/18722 0.195842492207128 0.326756388376761 SNCA/C4orf3/SGK1/PDE4B 4 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 2/138 111/18722 0.197307377046626 0.328216634979534 FN1/OSM 2 GO:0015718 monocarboxylic acid transport 2/138 111/18722 0.197307377046626 0.328216634979534 IL1B/ANXA1 2 GO:0071867 response to monoamine 2/138 111/18722 0.197307377046626 0.328216634979534 SNCA/PDE4B 2 GO:0071869 response to catecholamine 2/138 111/18722 0.197307377046626 0.328216634979534 SNCA/PDE4B 2 GO:0090288 negative regulation of cellular response to growth factor stimulus 2/138 111/18722 0.197307377046626 0.328216634979534 FBN1/SKIL 2 GO:0034329 cell junction assembly 5/138 420/18722 0.198694681248873 0.328780738776044 FN1/SNCA/TLN1/ACTG1/IL1B 5 GO:0019674 NAD metabolic process 1/138 30/18722 0.199182294493859 0.328780738776044 LDHA 1 GO:0031571 mitotic G1 DNA damage checkpoint signaling 1/138 30/18722 0.199182294493859 0.328780738776044 PLK3 1 GO:0032480 negative regulation of type I interferon production 1/138 30/18722 0.199182294493859 0.328780738776044 REL 1 GO:0033137 negative regulation of peptidyl-serine phosphorylation 1/138 30/18722 0.199182294493859 0.328780738776044 DDIT4 1 GO:0036258 multivesicular body assembly 1/138 30/18722 0.199182294493859 0.328780738776044 CHMP5 1 GO:0036296 response to increased oxygen levels 1/138 30/18722 0.199182294493859 0.328780738776044 FAS 1 GO:0043032 positive regulation of macrophage activation 1/138 30/18722 0.199182294493859 0.328780738776044 JUND 1 GO:0045948 positive regulation of translational initiation 1/138 30/18722 0.199182294493859 0.328780738776044 PPP1R15A 1 GO:0046825 regulation of protein export from nucleus 1/138 30/18722 0.199182294493859 0.328780738776044 IL1B 1 GO:0051968 positive regulation of synaptic transmission, glutamatergic 1/138 30/18722 0.199182294493859 0.328780738776044 PTGS2 1 GO:0060218 hematopoietic stem cell differentiation 1/138 30/18722 0.199182294493859 0.328780738776044 OSM 1 GO:0140058 neuron projection arborization 1/138 30/18722 0.199182294493859 0.328780738776044 PHACTR1 1 GO:0001676 long-chain fatty acid metabolic process 2/138 112/18722 0.199985856371239 0.329911463118647 PTGS2/GPX1 2 GO:1902905 positive regulation of supramolecular fiber organization 3/138 209/18722 0.200289077747395 0.330215938015996 PLEK/GPX1/GPR65 3 GO:0006816 calcium ion transport 5/138 422/18722 0.201272254258107 0.331499445466608 PTGS2/SNCA/C4orf3/CXCR4/PDE4B 5 GO:0031396 regulation of protein ubiquitination 3/138 210/18722 0.202177144286993 0.331499445466608 IVNS1ABP/UBB/UBE2S 3 GO:0002708 positive regulation of lymphocyte mediated immunity 2/138 113/18722 0.202668715741046 0.331499445466608 IL1B/CD55 2 GO:0031623 receptor internalization 2/138 113/18722 0.202668715741046 0.331499445466608 CXCL8/SNCA 2 GO:0043414 macromolecule methylation 4/138 316/18722 0.20491575419648 0.331499445466608 FOS/BTG2/ETF1/GSPT1 4 GO:0001782 B cell homeostasis 1/138 31/18722 0.205094601542856 0.331499445466608 HIF1A 1 GO:0002828 regulation of type 2 immune response 1/138 31/18722 0.205094601542856 0.331499445466608 ANXA1 1 GO:0006779 porphyrin-containing compound biosynthetic process 1/138 31/18722 0.205094601542856 0.331499445466608 ALAS2 1 GO:0016577 histone demethylation 1/138 31/18722 0.205094601542856 0.331499445466608 JMJD6 1 GO:0030212 hyaluronan metabolic process 1/138 31/18722 0.205094601542856 0.331499445466608 IL1B 1 GO:0031114 regulation of microtubule depolymerization 1/138 31/18722 0.205094601542856 0.331499445466608 MID1IP1 1 GO:0032509 endosome transport via multivesicular body sorting pathway 1/138 31/18722 0.205094601542856 0.331499445466608 CHMP5 1 GO:0033014 tetrapyrrole biosynthetic process 1/138 31/18722 0.205094601542856 0.331499445466608 ALAS2 1 GO:0033238 regulation of cellular amine metabolic process 1/138 31/18722 0.205094601542856 0.331499445466608 SNCA 1 GO:0036257 multivesicular body organization 1/138 31/18722 0.205094601542856 0.331499445466608 CHMP5 1 GO:0044819 mitotic G1/S transition checkpoint signaling 1/138 31/18722 0.205094601542856 0.331499445466608 PLK3 1 GO:0045987 positive regulation of smooth muscle contraction 1/138 31/18722 0.205094601542856 0.331499445466608 PTGS2 1 GO:0048384 retinoic acid receptor signaling pathway 1/138 31/18722 0.205094601542856 0.331499445466608 KLF2 1 GO:0048566 embryonic digestive tract development 1/138 31/18722 0.205094601542856 0.331499445466608 CXCL8 1 GO:0050482 arachidonic acid secretion 1/138 31/18722 0.205094601542856 0.331499445466608 ANXA1 1 GO:0051443 positive regulation of ubiquitin-protein transferase activity 1/138 31/18722 0.205094601542856 0.331499445466608 UBE2S 1 GO:0060795 cell fate commitment involved in formation of primary germ layer 1/138 31/18722 0.205094601542856 0.331499445466608 ETS2 1 GO:0070528 protein kinase C signaling 1/138 31/18722 0.205094601542856 0.331499445466608 PLEK 1 GO:0070633 transepithelial transport 1/138 31/18722 0.205094601542856 0.331499445466608 ACTG1 1 GO:0071480 cellular response to gamma radiation 1/138 31/18722 0.205094601542856 0.331499445466608 EGR1 1 GO:1901797 negative regulation of signal transduction by p53 class mediator 1/138 31/18722 0.205094601542856 0.331499445466608 MIF 1 GO:1903963 arachidonate transport 1/138 31/18722 0.205094601542856 0.331499445466608 ANXA1 1 GO:2000144 positive regulation of DNA-templated transcription, initiation 1/138 31/18722 0.205094601542856 0.331499445466608 JUN 1 GO:0002244 hematopoietic progenitor cell differentiation 2/138 114/18722 0.205355747029979 0.331499445466608 OSM/PLEK 2 GO:0007041 lysosomal transport 2/138 114/18722 0.205355747029979 0.331499445466608 CHMP5/RHOB 2 GO:0019751 polyol metabolic process 2/138 114/18722 0.205355747029979 0.331499445466608 PLEK/SNCA 2 GO:0022904 respiratory electron transport chain 2/138 114/18722 0.205355747029979 0.331499445466608 SNCA/UQCRH 2 GO:0046660 female sex differentiation 2/138 114/18722 0.205355747029979 0.331499445466608 CEBPB/UBB 2 GO:0051261 protein depolymerization 2/138 114/18722 0.205355747029979 0.331499445466608 PLEK/MID1IP1 2 GO:1901800 positive regulation of proteasomal protein catabolic process 2/138 114/18722 0.205355747029979 0.331499445466608 TRIB1/PLK3 2 GO:1904892 regulation of receptor signaling pathway via STAT 2/138 114/18722 0.205355747029979 0.331499445466608 SOCS3/BCL3 2 GO:0000077 DNA damage checkpoint signaling 2/138 115/18722 0.20804674489962 0.33506602491646 PPP1R10/PLK3 2 GO:0030278 regulation of ossification 2/138 115/18722 0.20804674489962 0.33506602491646 SRGN/HIF1A 2 GO:0071675 regulation of mononuclear cell migration 2/138 115/18722 0.20804674489962 0.33506602491646 DUSP1/HMGB1 2 GO:1901989 positive regulation of cell cycle phase transition 2/138 115/18722 0.20804674489962 0.33506602491646 PPP1R10/ANXA1 2 GO:0007006 mitochondrial membrane organization 2/138 116/18722 0.210741506769925 0.33664657315471 BNIP3L/SNCA 2 GO:0010667 negative regulation of cardiac muscle cell apoptotic process 1/138 32/18722 0.210963572972265 0.33664657315471 PPP1R10 1 GO:0010743 regulation of macrophage derived foam cell differentiation 1/138 32/18722 0.210963572972265 0.33664657315471 NFKBIA 1 GO:0030431 sleep 1/138 32/18722 0.210963572972265 0.33664657315471 FOS 1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 1/138 32/18722 0.210963572972265 0.33664657315471 LRG1 1 GO:0033687 osteoblast proliferation 1/138 32/18722 0.210963572972265 0.33664657315471 JUNB 1 GO:0046475 glycerophospholipid catabolic process 1/138 32/18722 0.210963572972265 0.33664657315471 PRDX6 1 GO:0050685 positive regulation of mRNA processing 1/138 32/18722 0.210963572972265 0.33664657315471 PRDX6 1 GO:0060323 head morphogenesis 1/138 32/18722 0.210963572972265 0.33664657315471 CSRNP1 1 GO:0071875 adrenergic receptor signaling pathway 1/138 32/18722 0.210963572972265 0.33664657315471 PDE4B 1 GO:0090022 regulation of neutrophil chemotaxis 1/138 32/18722 0.210963572972265 0.33664657315471 CXCL8 1 GO:0097345 mitochondrial outer membrane permeabilization 1/138 32/18722 0.210963572972265 0.33664657315471 BNIP3L 1 GO:1900745 positive regulation of p38MAPK cascade 1/138 32/18722 0.210963572972265 0.33664657315471 IL1B 1 GO:1901532 regulation of hematopoietic progenitor cell differentiation 1/138 32/18722 0.210963572972265 0.33664657315471 OSM 1 GO:1901889 negative regulation of cell junction assembly 1/138 32/18722 0.210963572972265 0.33664657315471 IL1B 1 GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 1/138 32/18722 0.210963572972265 0.33664657315471 LRG1 1 GO:0014902 myotube differentiation 2/138 117/18722 0.21343983279022 0.340402896650534 GPX1/MYH9 2 GO:0002335 mature B cell differentiation 1/138 33/18722 0.216789524118858 0.341827334630472 BCL3 1 GO:0006482 protein demethylation 1/138 33/18722 0.216789524118858 0.341827334630472 JMJD6 1 GO:0006891 intra-Golgi vesicle-mediated transport 1/138 33/18722 0.216789524118858 0.341827334630472 GABARAPL2 1 GO:0008214 protein dealkylation 1/138 33/18722 0.216789524118858 0.341827334630472 JMJD6 1 GO:0010165 response to X-ray 1/138 33/18722 0.216789524118858 0.341827334630472 ANXA1 1 GO:0010259 multicellular organism aging 1/138 33/18722 0.216789524118858 0.341827334630472 SERP1 1 GO:0010737 protein kinase A signaling 1/138 33/18722 0.216789524118858 0.341827334630472 MIF 1 GO:0032633 interleukin-4 production 1/138 33/18722 0.216789524118858 0.341827334630472 CEBPB 1 GO:0032673 regulation of interleukin-4 production 1/138 33/18722 0.216789524118858 0.341827334630472 CEBPB 1 GO:0033198 response to ATP 1/138 33/18722 0.216789524118858 0.341827334630472 PTGS2 1 GO:0034110 regulation of homotypic cell-cell adhesion 1/138 33/18722 0.216789524118858 0.341827334630472 PLAUR 1 GO:0035025 positive regulation of Rho protein signal transduction 1/138 33/18722 0.216789524118858 0.341827334630472 GPR65 1 GO:0046320 regulation of fatty acid oxidation 1/138 33/18722 0.216789524118858 0.341827334630472 IRS2 1 GO:0048048 embryonic eye morphogenesis 1/138 33/18722 0.216789524118858 0.341827334630472 FBN1 1 GO:0050974 detection of mechanical stimulus involved in sensory perception 1/138 33/18722 0.216789524118858 0.341827334630472 CXCR4 1 GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 1/138 33/18722 0.216789524118858 0.341827334630472 HMGB1 1 GO:0071353 cellular response to interleukin-4 1/138 33/18722 0.216789524118858 0.341827334630472 NFIL3 1 GO:0099174 regulation of presynapse organization 1/138 33/18722 0.216789524118858 0.341827334630472 SNCA 1 GO:1902692 regulation of neuroblast proliferation 1/138 33/18722 0.216789524118858 0.341827334630472 HIF1A 1 GO:1905606 regulation of presynapse assembly 1/138 33/18722 0.216789524118858 0.341827334630472 SNCA 1 GO:0031398 positive regulation of protein ubiquitination 2/138 119/18722 0.21884639135284 0.344875145603031 UBB/UBE2S 2 GO:0048593 camera-type eye morphogenesis 2/138 120/18722 0.221554237583461 0.347208527724045 HIF1A/HMGN1 2 GO:0051897 positive regulation of protein kinase B signaling 2/138 120/18722 0.221554237583461 0.347208527724045 OSM/GPX1 2 GO:0071901 negative regulation of protein serine/threonine kinase activity 2/138 120/18722 0.221554237583461 0.347208527724045 DUSP1/IL1B 2 GO:0002446 neutrophil mediated immunity 1/138 34/18722 0.222572768041572 0.347208527724045 TREM1 1 GO:0007616 long-term memory 1/138 34/18722 0.222572768041572 0.347208527724045 SGK1 1 GO:0030851 granulocyte differentiation 1/138 34/18722 0.222572768041572 0.347208527724045 TRIB1 1 GO:0035308 negative regulation of protein dephosphorylation 1/138 34/18722 0.222572768041572 0.347208527724045 PPP1R15A 1 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus 1/138 34/18722 0.222572768041572 0.347208527724045 RIOK3 1 GO:0043276 anoikis 1/138 34/18722 0.222572768041572 0.347208527724045 MCL1 1 GO:0048536 spleen development 1/138 34/18722 0.222572768041572 0.347208527724045 BCL3 1 GO:0048741 skeletal muscle fiber development 1/138 34/18722 0.222572768041572 0.347208527724045 GPX1 1 GO:0050869 negative regulation of B cell activation 1/138 34/18722 0.222572768041572 0.347208527724045 SAMSN1 1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 1/138 34/18722 0.222572768041572 0.347208527724045 GPR65 1 GO:0070232 regulation of T cell apoptotic process 1/138 34/18722 0.222572768041572 0.347208527724045 HIF1A 1 GO:0086004 regulation of cardiac muscle cell contraction 1/138 34/18722 0.222572768041572 0.347208527724045 PDE4B 1 GO:0090075 relaxation of muscle 1/138 34/18722 0.222572768041572 0.347208527724045 PDE4B 1 GO:0098751 bone cell development 1/138 34/18722 0.222572768041572 0.347208527724045 FBN1 1 GO:2000758 positive regulation of peptidyl-lysine acetylation 1/138 34/18722 0.222572768041572 0.347208527724045 IL1B 1 GO:0008406 gonad development 3/138 221/18722 0.223209654206695 0.348006984681923 CEBPB/UBB/HMGB2 3 GO:0000280 nuclear division 5/138 439/18722 0.22362770318171 0.348463548686841 DUSP1/IL1B/UBB/CHMP5/UBE2S 5 GO:0002224 toll-like receptor signaling pathway 2/138 121/18722 0.224264875284548 0.348675501629552 NFKBIA/HMGB1 2 GO:0002455 humoral immune response mediated by circulating immunoglobulin 2/138 121/18722 0.224264875284548 0.348675501629552 CD55/BCL3 2 GO:0042177 negative regulation of protein catabolic process 2/138 121/18722 0.224264875284548 0.348675501629552 GABARAPL2/SNCA 2 GO:0045931 positive regulation of mitotic cell cycle 2/138 121/18722 0.224264875284548 0.348675501629552 PPP1R10/ANXA1 2 GO:0051090 regulation of DNA-binding transcription factor activity 5/138 440/18722 0.22496616632819 0.349570542094558 TRIB1/NFKBIA/IL1B/SGK1/BCL3 5 GO:0031109 microtubule polymerization or depolymerization 2/138 122/18722 0.226978117826715 0.352215516652889 SNCA/MID1IP1 2 GO:0006298 mismatch repair 1/138 35/18722 0.228313615537841 0.352215516652889 HMGB1 1 GO:0010664 negative regulation of striated muscle cell apoptotic process 1/138 35/18722 0.228313615537841 0.352215516652889 PPP1R10 1 GO:0010837 regulation of keratinocyte proliferation 1/138 35/18722 0.228313615537841 0.352215516652889 ZFP36 1 GO:0019068 virion assembly 1/138 35/18722 0.228313615537841 0.352215516652889 CHMP5 1 GO:0033280 response to vitamin D 1/138 35/18722 0.228313615537841 0.352215516652889 PTGS2 1 GO:0039694 viral RNA genome replication 1/138 35/18722 0.228313615537841 0.352215516652889 CXCL8 1 GO:0043243 positive regulation of protein-containing complex disassembly 1/138 35/18722 0.228313615537841 0.352215516652889 PLEK 1 GO:0045907 positive regulation of vasoconstriction 1/138 35/18722 0.228313615537841 0.352215516652889 PTGS2 1 GO:0046640 regulation of alpha-beta T cell proliferation 1/138 35/18722 0.228313615537841 0.352215516652889 CD55 1 GO:0060236 regulation of mitotic spindle organization 1/138 35/18722 0.228313615537841 0.352215516652889 CHMP5 1 GO:0097421 liver regeneration 1/138 35/18722 0.228313615537841 0.352215516652889 CEBPB 1 GO:0098810 neurotransmitter reuptake 1/138 35/18722 0.228313615537841 0.352215516652889 SNCA 1 GO:0031570 DNA integrity checkpoint signaling 2/138 123/18722 0.229693781141574 0.353952266288483 PPP1R10/PLK3 2 GO:0050852 T cell receptor signaling pathway 2/138 123/18722 0.229693781141574 0.353952266288483 NFKBIZ/PDE4B 2 GO:0006364 rRNA processing 3/138 225/18722 0.230965581087371 0.355518369560926 RIOK3/DDX21/RPL7 3 GO:0016485 protein processing 3/138 225/18722 0.230965581087371 0.355518369560926 SRGN/MYH9/IL1R2 3 GO:0042113 B cell activation 4/138 334/18722 0.232835829951144 0.356657415153208 SAMSN1/BCL3/IRS2/MIF 4 GO:0008207 C21-steroid hormone metabolic process 1/138 36/18722 0.234012375159812 0.356657415153208 EGR1 1 GO:0010923 negative regulation of phosphatase activity 1/138 36/18722 0.234012375159812 0.356657415153208 PPP1R15A 1 GO:0014046 dopamine secretion 1/138 36/18722 0.234012375159812 0.356657415153208 SNCA 1 GO:0014059 regulation of dopamine secretion 1/138 36/18722 0.234012375159812 0.356657415153208 SNCA 1 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 1/138 36/18722 0.234012375159812 0.356657415153208 HIF1A 1 GO:0038179 neurotrophin signaling pathway 1/138 36/18722 0.234012375159812 0.356657415153208 DDIT4 1 GO:0042119 neutrophil activation 1/138 36/18722 0.234012375159812 0.356657415153208 CXCL8 1 GO:0045652 regulation of megakaryocyte differentiation 1/138 36/18722 0.234012375159812 0.356657415153208 HMGB2 1 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway 1/138 36/18722 0.234012375159812 0.356657415153208 PLAUR 1 GO:0045746 negative regulation of Notch signaling pathway 1/138 36/18722 0.234012375159812 0.356657415153208 NFKBIA 1 GO:0051354 negative regulation of oxidoreductase activity 1/138 36/18722 0.234012375159812 0.356657415153208 SNCA 1 GO:0051955 regulation of amino acid transport 1/138 36/18722 0.234012375159812 0.356657415153208 SNCA 1 GO:0060251 regulation of glial cell proliferation 1/138 36/18722 0.234012375159812 0.356657415153208 IL1B 1 GO:0070306 lens fiber cell differentiation 1/138 36/18722 0.234012375159812 0.356657415153208 SKIL 1 GO:0070670 response to interleukin-4 1/138 36/18722 0.234012375159812 0.356657415153208 NFIL3 1 GO:0070897 transcription preinitiation complex assembly 1/138 36/18722 0.234012375159812 0.356657415153208 HMGB1 1 GO:0097009 energy homeostasis 1/138 36/18722 0.234012375159812 0.356657415153208 UBB 1 GO:0045137 development of primary sexual characteristics 3/138 227/18722 0.234862554957317 0.357561537443223 CEBPB/UBB/HMGB2 3 GO:0098657 import into cell 3/138 227/18722 0.234862554957317 0.357561537443223 SNCA/SLC2A3/IRS2 3 GO:0006874 cellular calcium ion homeostasis 5/138 448/18722 0.235760159975451 0.358535806126601 SNCA/HMGB1/CXCR4/GPR65/CD55 5 GO:0010876 lipid localization 5/138 448/18722 0.235760159975451 0.358535806126601 NFKBIA/IL1B/ANXA1/PLIN2/IRS2 5 GO:0032386 regulation of intracellular transport 4/138 337/18722 0.237580216358733 0.360735429983961 PTGS2/BNIP3L/IL1B/PLK3 4 GO:0031929 TOR signaling 2/138 126/18722 0.237853492885275 0.360735429983961 DDIT4/HIF1A 2 GO:0032874 positive regulation of stress-activated MAPK cascade 2/138 126/18722 0.237853492885275 0.360735429983961 HMGB1/IL1B 2 GO:0071695 anatomical structure maturation 3/138 229/18722 0.238771422162381 0.360735429983961 KLF2/HIF1A/FAM210B 3 GO:0001655 urogenital system development 4/138 338/18722 0.239166888000923 0.360735429983961 EGR1/FBN1/ANXA1/JMJD6 4 GO:0006904 vesicle docking involved in exocytosis 1/138 37/18722 0.23966935323045 0.360735429983961 PLEK 1 GO:0014904 myotube cell development 1/138 37/18722 0.23966935323045 0.360735429983961 GPX1 1 GO:0032885 regulation of polysaccharide biosynthetic process 1/138 37/18722 0.23966935323045 0.360735429983961 IRS2 1 GO:0033120 positive regulation of RNA splicing 1/138 37/18722 0.23966935323045 0.360735429983961 PRDX6 1 GO:0033363 secretory granule organization 1/138 37/18722 0.23966935323045 0.360735429983961 SRGN 1 GO:0043029 T cell homeostasis 1/138 37/18722 0.23966935323045 0.360735429983961 FAS 1 GO:0045616 regulation of keratinocyte differentiation 1/138 37/18722 0.23966935323045 0.360735429983961 ZFP36 1 GO:0045730 respiratory burst 1/138 37/18722 0.23966935323045 0.360735429983961 CD55 1 GO:0060428 lung epithelium development 1/138 37/18722 0.23966935323045 0.360735429983961 KLF2 1 GO:0071542 dopaminergic neuron differentiation 1/138 37/18722 0.23966935323045 0.360735429983961 HIF1A 1 GO:0071985 multivesicular body sorting pathway 1/138 37/18722 0.23966935323045 0.360735429983961 CHMP5 1 GO:0097484 dendrite extension 1/138 37/18722 0.23966935323045 0.360735429983961 CXCR4 1 GO:1900016 negative regulation of cytokine production involved in inflammatory response 1/138 37/18722 0.23966935323045 0.360735429983961 IL1R2 1 GO:1904358 positive regulation of telomere maintenance via telomere lengthening 1/138 37/18722 0.23966935323045 0.360735429983961 HNRNPA2B1 1 GO:0030048 actin filament-based movement 2/138 127/18722 0.240577048882448 0.361549900140791 MYH9/PDE4B 2 GO:0048565 digestive tract development 2/138 127/18722 0.240577048882448 0.361549900140791 CXCL8/HIF1A 2 GO:0045055 regulated exocytosis 3/138 230/18722 0.240730134732621 0.361549900140791 PLEK/SNCA/MYH9 3 GO:0045333 cellular respiration 3/138 230/18722 0.240730134732621 0.361549900140791 SNCA/HIF1A/UQCRH 3 GO:0003012 muscle system process 5/138 452/18722 0.241212180317843 0.362078477791024 PTGS2/TPM3/CXCR4/IL1B/PDE4B 5 GO:0045732 positive regulation of protein catabolic process 3/138 231/18722 0.242691604066429 0.364102821626346 TRIB1/IL1B/PLK3 3 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 2/138 128/18722 0.243302142784324 0.364456886434088 HMGB1/IL1B 2 GO:0007094 mitotic spindle assembly checkpoint signaling 1/138 38/18722 0.245284853859521 0.364456886434088 DUSP1 1 GO:0010742 macrophage derived foam cell differentiation 1/138 38/18722 0.245284853859521 0.364456886434088 NFKBIA 1 GO:0032373 positive regulation of sterol transport 1/138 38/18722 0.245284853859521 0.364456886434088 NFKBIA 1 GO:0032376 positive regulation of cholesterol transport 1/138 38/18722 0.245284853859521 0.364456886434088 NFKBIA 1 GO:0046633 alpha-beta T cell proliferation 1/138 38/18722 0.245284853859521 0.364456886434088 CD55 1 GO:0046676 negative regulation of insulin secretion 1/138 38/18722 0.245284853859521 0.364456886434088 MIDN 1 GO:0048246 macrophage chemotaxis 1/138 38/18722 0.245284853859521 0.364456886434088 MIF 1 GO:0048713 regulation of oligodendrocyte differentiation 1/138 38/18722 0.245284853859521 0.364456886434088 CXCR4 1 GO:0071173 spindle assembly checkpoint signaling 1/138 38/18722 0.245284853859521 0.364456886434088 DUSP1 1 GO:0071174 mitotic spindle checkpoint signaling 1/138 38/18722 0.245284853859521 0.364456886434088 DUSP1 1 GO:0071392 cellular response to estradiol stimulus 1/138 38/18722 0.245284853859521 0.364456886434088 FAM210B 1 GO:0072538 T-helper 17 type immune response 1/138 38/18722 0.245284853859521 0.364456886434088 NFKBIZ 1 GO:0090077 foam cell differentiation 1/138 38/18722 0.245284853859521 0.364456886434088 NFKBIA 1 GO:1901186 positive regulation of ERBB signaling pathway 1/138 38/18722 0.245284853859521 0.364456886434088 PLAUR 1 GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 1/138 38/18722 0.245284853859521 0.364456886434088 BNIP3L 1 GO:1903580 positive regulation of ATP metabolic process 1/138 38/18722 0.245284853859521 0.364456886434088 HIF1A 1 GO:2000279 negative regulation of DNA biosynthetic process 1/138 38/18722 0.245284853859521 0.364456886434088 DUSP1 1 GO:0006638 neutral lipid metabolic process 2/138 129/18722 0.246028605327412 0.365366920291456 GPX1/SNCA 2 GO:0006956 complement activation 2/138 130/18722 0.248756269624524 0.369220639128028 IL1B/CD55 2 GO:0002347 response to tumor cell 1/138 39/18722 0.250859178959467 0.370366628670662 HMGB1 1 GO:0010463 mesenchymal cell proliferation 1/138 39/18722 0.250859178959467 0.370366628670662 IRS2 1 GO:0016572 histone phosphorylation 1/138 39/18722 0.250859178959467 0.370366628670662 IL1B 1 GO:0031577 spindle checkpoint signaling 1/138 39/18722 0.250859178959467 0.370366628670662 DUSP1 1 GO:0042417 dopamine metabolic process 1/138 39/18722 0.250859178959467 0.370366628670662 SNCA 1 GO:0046326 positive regulation of glucose import 1/138 39/18722 0.250859178959467 0.370366628670662 IRS2 1 GO:0051154 negative regulation of striated muscle cell differentiation 1/138 39/18722 0.250859178959467 0.370366628670662 YBX1 1 GO:0071548 response to dexamethasone 1/138 39/18722 0.250859178959467 0.370366628670662 DDIT4 1 GO:0090224 regulation of spindle organization 1/138 39/18722 0.250859178959467 0.370366628670662 CHMP5 1 GO:1903115 regulation of actin filament-based movement 1/138 39/18722 0.250859178959467 0.370366628670662 PDE4B 1 GO:0000723 telomere maintenance 2/138 131/18722 0.251484971139378 0.370700569216572 PPP1R10/HNRNPA2B1 2 GO:0019079 viral genome replication 2/138 131/18722 0.251484971139378 0.370700569216572 CXCL8/DDX5 2 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2/138 131/18722 0.251484971139378 0.370700569216572 FBN1/SKIL 2 GO:0055074 calcium ion homeostasis 5/138 460/18722 0.252218551235744 0.371585086336197 SNCA/HMGB1/CXCR4/GPR65/CD55 5 GO:0016072 rRNA metabolic process 3/138 236/18722 0.252537812171797 0.371661941445854 RIOK3/DDX21/RPL7 3 GO:0090068 positive regulation of cell cycle process 3/138 236/18722 0.252537812171797 0.371661941445854 PPP1R10/IL1B/ANXA1 3 GO:0006936 muscle contraction 4/138 347/18722 0.25355662257421 0.37276707904069 PTGS2/TPM3/CXCR4/PDE4B 4 GO:0010639 negative regulation of organelle organization 4/138 347/18722 0.25355662257421 0.37276707904069 DUSP1/GPX1/SNCA/MID1IP1 4 GO:0035264 multicellular organism growth 2/138 132/18722 0.25421454766144 0.373537004298726 KLF2/TAF10 2 GO:1901617 organic hydroxy compound biosynthetic process 3/138 237/18722 0.25451433293315 0.373780152270689 PLEK/SNCA/IDI1 3 GO:0009187 cyclic nucleotide metabolic process 1/138 40/18722 0.256392628261164 0.37431586027208 PDE4B 1 GO:0010543 regulation of platelet activation 1/138 40/18722 0.256392628261164 0.37431586027208 PLEK 1 GO:0032892 positive regulation of organic acid transport 1/138 40/18722 0.256392628261164 0.37431586027208 IL1B 1 GO:0044275 cellular carbohydrate catabolic process 1/138 40/18722 0.256392628261164 0.37431586027208 HMGB1 1 GO:0045740 positive regulation of DNA replication 1/138 40/18722 0.256392628261164 0.37431586027208 JUN 1 GO:0045841 negative regulation of mitotic metaphase/anaphase transition 1/138 40/18722 0.256392628261164 0.37431586027208 DUSP1 1 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 1/138 40/18722 0.256392628261164 0.37431586027208 SNCA 1 GO:0070266 necroptotic process 1/138 40/18722 0.256392628261164 0.37431586027208 FAS 1 GO:0072210 metanephric nephron development 1/138 40/18722 0.256392628261164 0.37431586027208 EGR1 1 GO:1901020 negative regulation of calcium ion transmembrane transporter activity 1/138 40/18722 0.256392628261164 0.37431586027208 C4orf3 1 GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 1/138 40/18722 0.256392628261164 0.37431586027208 BNIP3L 1 GO:0051259 protein complex oligomerization 3/138 238/18722 0.256493117333402 0.37431586027208 SNCA/JMJD6/MIF 3 GO:0006997 nucleus organization 2/138 133/18722 0.256944839281015 0.374386119224642 CHMP5/HMGB2 2 GO:0046328 regulation of JNK cascade 2/138 133/18722 0.256944839281015 0.374386119224642 HMGB1/IL1B 2 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 2/138 133/18722 0.256944839281015 0.374386119224642 TRIB1/PLK3 2 GO:0002449 lymphocyte mediated immunity 4/138 350/18722 0.258394085223186 0.376300753101061 HMGB1/IL1B/CD55/BCL3 4 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 2/138 134/18722 0.25967568836456 0.377969372760759 TRIB1/PLK3 2 GO:0032886 regulation of microtubule-based process 3/138 240/18722 0.260457201275789 0.378908725117889 SNCA/CHMP5/MID1IP1 3 GO:0006887 exocytosis 4/138 352/18722 0.26162952797664 0.379202572650464 PLEK/SNCA/MYH9/ANXA1 4 GO:0032735 positive regulation of interleukin-12 production 1/138 41/18722 0.26188549932957 0.379202572650464 HMGB1 1 GO:0042307 positive regulation of protein import into nucleus 1/138 41/18722 0.26188549932957 0.379202572650464 PTGS2 1 GO:0060612 adipose tissue development 1/138 41/18722 0.26188549932957 0.379202572650464 UBB 1 GO:0071470 cellular response to osmotic stress 1/138 41/18722 0.26188549932957 0.379202572650464 PTGS2 1 GO:1900371 regulation of purine nucleotide biosynthetic process 1/138 41/18722 0.26188549932957 0.379202572650464 SNCA 1 GO:1901385 regulation of voltage-gated calcium channel activity 1/138 41/18722 0.26188549932957 0.379202572650464 PDE4B 1 GO:1902622 regulation of neutrophil migration 1/138 41/18722 0.26188549932957 0.379202572650464 CXCL8 1 GO:1905521 regulation of macrophage migration 1/138 41/18722 0.26188549932957 0.379202572650464 MIF 1 GO:0001101 response to acid chemical 2/138 135/18722 0.262406939530242 0.379416674571393 CEBPB/KLF2 2 GO:0002687 positive regulation of leukocyte migration 2/138 135/18722 0.262406939530242 0.379416674571393 CXCL8/HMGB1 2 GO:0060047 heart contraction 3/138 241/18722 0.262442363833967 0.379416674571393 GPX1/CXCR4/PDE4B 3 GO:0002764 immune response-regulating signaling pathway 5/138 468/18722 0.263351062752199 0.380532714246817 NFKBIA/NFKBIZ/HMGB1/RIOK3/PDE4B 5 GO:0015711 organic anion transport 4/138 354/18722 0.264872991895351 0.38253323115971 SNCA/SLC2A3/IL1B/ANXA1 4 GO:0043543 protein acylation 3/138 243/18722 0.266418590397768 0.382913997803957 SNCA/IL1B/TAF10 3 GO:0007520 myoblast fusion 1/138 42/18722 0.267338087579263 0.382913997803957 MYH9 1 GO:0009154 purine ribonucleotide catabolic process 1/138 42/18722 0.267338087579263 0.382913997803957 PDE4B 1 GO:0014912 negative regulation of smooth muscle cell migration 1/138 42/18722 0.267338087579263 0.382913997803957 TRIB1 1 GO:0021879 forebrain neuron differentiation 1/138 42/18722 0.267338087579263 0.382913997803957 UBB 1 GO:0030808 regulation of nucleotide biosynthetic process 1/138 42/18722 0.267338087579263 0.382913997803957 SNCA 1 GO:0032689 negative regulation of interferon-gamma production 1/138 42/18722 0.267338087579263 0.382913997803957 HMGB1 1 GO:0033574 response to testosterone 1/138 42/18722 0.267338087579263 0.382913997803957 DUSP1 1 GO:0042168 heme metabolic process 1/138 42/18722 0.267338087579263 0.382913997803957 ALAS2 1 GO:0045687 positive regulation of glial cell differentiation 1/138 42/18722 0.267338087579263 0.382913997803957 CXCR4 1 GO:0045773 positive regulation of axon extension 1/138 42/18722 0.267338087579263 0.382913997803957 FN1 1 GO:0048489 synaptic vesicle transport 1/138 42/18722 0.267338087579263 0.382913997803957 SNCA 1 GO:0051602 response to electrical stimulus 1/138 42/18722 0.267338087579263 0.382913997803957 BTG2 1 GO:0072595 maintenance of protein localization in organelle 1/138 42/18722 0.267338087579263 0.382913997803957 MORC3 1 GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle 1/138 42/18722 0.267338087579263 0.382913997803957 DUSP1 1 GO:2001222 regulation of neuron migration 1/138 42/18722 0.267338087579263 0.382913997803957 PHACTR1 1 GO:0007266 Rho protein signal transduction 2/138 137/18722 0.267870037694179 0.3830844372574 GPR65/RHOB 2 GO:0055123 digestive system development 2/138 137/18722 0.267870037694179 0.3830844372574 CXCL8/HIF1A 2 GO:0060048 cardiac muscle contraction 2/138 137/18722 0.267870037694179 0.3830844372574 CXCR4/PDE4B 2 GO:0032956 regulation of actin cytoskeleton organization 4/138 357/18722 0.269752569134556 0.385507953247687 PLEK/ACTG1/GPR65/RHOB 4 GO:0017148 negative regulation of translation 3/138 245/18722 0.27040223688013 0.385507953247687 BTG2/ZFP36/YBX1 3 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 2/138 138/18722 0.270601584970546 0.385507953247687 UBB/UBE2S 2 GO:0001504 neurotransmitter uptake 1/138 43/18722 0.272750686289866 0.385507953247687 SNCA 1 GO:0001709 cell fate determination 1/138 43/18722 0.272750686289866 0.385507953247687 MCL1 1 GO:0002861 regulation of inflammatory response to antigenic stimulus 1/138 43/18722 0.272750686289866 0.385507953247687 GPX1 1 GO:0006284 base-excision repair 1/138 43/18722 0.272750686289866 0.385507953247687 HMGB1 1 GO:0009268 response to pH 1/138 43/18722 0.272750686289866 0.385507953247687 GPR65 1 GO:0010171 body morphogenesis 1/138 43/18722 0.272750686289866 0.385507953247687 CSRNP1 1 GO:0033046 negative regulation of sister chromatid segregation 1/138 43/18722 0.272750686289866 0.385507953247687 DUSP1 1 GO:0033048 negative regulation of mitotic sister chromatid segregation 1/138 43/18722 0.272750686289866 0.385507953247687 DUSP1 1 GO:0035794 positive regulation of mitochondrial membrane permeability 1/138 43/18722 0.272750686289866 0.385507953247687 BNIP3L 1 GO:0036230 granulocyte activation 1/138 43/18722 0.272750686289866 0.385507953247687 CXCL8 1 GO:0042181 ketone biosynthetic process 1/138 43/18722 0.272750686289866 0.385507953247687 EGR1 1 GO:0045840 positive regulation of mitotic nuclear division 1/138 43/18722 0.272750686289866 0.385507953247687 IL1B 1 GO:0045981 positive regulation of nucleotide metabolic process 1/138 43/18722 0.272750686289866 0.385507953247687 HIF1A 1 GO:0046717 acid secretion 1/138 43/18722 0.272750686289866 0.385507953247687 SGK1 1 GO:0090278 negative regulation of peptide hormone secretion 1/138 43/18722 0.272750686289866 0.385507953247687 MIDN 1 GO:0120178 steroid hormone biosynthetic process 1/138 43/18722 0.272750686289866 0.385507953247687 EGR1 1 GO:0140353 lipid export from cell 1/138 43/18722 0.272750686289866 0.385507953247687 IL1B 1 GO:1900544 positive regulation of purine nucleotide metabolic process 1/138 43/18722 0.272750686289866 0.385507953247687 HIF1A 1 GO:1904591 positive regulation of protein import 1/138 43/18722 0.272750686289866 0.385507953247687 PTGS2 1 GO:2000816 negative regulation of mitotic sister chromatid separation 1/138 43/18722 0.272750686289866 0.385507953247687 DUSP1 1 GO:0051052 regulation of DNA metabolic process 4/138 359/18722 0.273014771514981 0.385685334581824 DUSP1/HMGB1/PPP1R10/HNRNPA2B1 4 GO:0030216 keratinocyte differentiation 2/138 139/18722 0.273332934837988 0.385743183394585 ZFP36/ANXA1 2 GO:0051783 regulation of nuclear division 2/138 139/18722 0.273332934837988 0.385743183394585 DUSP1/IL1B 2 GO:0007292 female gamete generation 2/138 140/18722 0.276063942814601 0.38910982966315 PTGS2/UBB 2 GO:0033002 muscle cell proliferation 3/138 248/18722 0.276390454178787 0.38910982966315 PTGS2/TRIB1/JUN 3 GO:0002066 columnar/cuboidal epithelial cell development 1/138 44/18722 0.278123586621361 0.38910982966315 HIF1A 1 GO:0002792 negative regulation of peptide secretion 1/138 44/18722 0.278123586621361 0.38910982966315 MIDN 1 GO:0005978 glycogen biosynthetic process 1/138 44/18722 0.278123586621361 0.38910982966315 IRS2 1 GO:0008542 visual learning 1/138 44/18722 0.278123586621361 0.38910982966315 HIF1A 1 GO:0009250 glucan biosynthetic process 1/138 44/18722 0.278123586621361 0.38910982966315 IRS2 1 GO:0030521 androgen receptor signaling pathway 1/138 44/18722 0.278123586621361 0.38910982966315 DDX5 1 GO:0031295 T cell costimulation 1/138 44/18722 0.278123586621361 0.38910982966315 MAP3K8 1 GO:0032620 interleukin-17 production 1/138 44/18722 0.278123586621361 0.38910982966315 OSM 1 GO:0032660 regulation of interleukin-17 production 1/138 44/18722 0.278123586621361 0.38910982966315 OSM 1 GO:0044058 regulation of digestive system process 1/138 44/18722 0.278123586621361 0.38910982966315 SGK1 1 GO:0046006 regulation of activated T cell proliferation 1/138 44/18722 0.278123586621361 0.38910982966315 HMGB1 1 GO:0060324 face development 1/138 44/18722 0.278123586621361 0.38910982966315 CSRNP1 1 GO:0062208 positive regulation of pattern recognition receptor signaling pathway 1/138 44/18722 0.278123586621361 0.38910982966315 HMGB1 1 GO:1903214 regulation of protein targeting to mitochondrion 1/138 44/18722 0.278123586621361 0.38910982966315 BNIP3L 1 GO:1901988 negative regulation of cell cycle phase transition 3/138 249/18722 0.278389662730543 0.38910982966315 DUSP1/PPP1R10/PLK3 3 GO:0006119 oxidative phosphorylation 2/138 141/18722 0.278794466528322 0.38910982966315 SNCA/UQCRH 2 GO:0008584 male gonad development 2/138 141/18722 0.278794466528322 0.38910982966315 UBB/HMGB2 2 GO:0016241 regulation of macroautophagy 2/138 141/18722 0.278794466528322 0.38910982966315 BNIP3L/HIF1A 2 GO:0034341 response to interferon-gamma 2/138 141/18722 0.278794466528322 0.38910982966315 SNCA/ACTG1 2 GO:0048284 organelle fusion 2/138 141/18722 0.278794466528322 0.38910982966315 SNCA/ANXA1 2 GO:0032259 methylation 4/138 364/18722 0.281200137621016 0.391688702602947 FOS/BTG2/ETF1/GSPT1 4 GO:0046546 development of primary male sexual characteristics 2/138 142/18722 0.281524365694076 0.391688702602947 UBB/HMGB2 2 GO:2000045 regulation of G1/S transition of mitotic cell cycle 2/138 142/18722 0.281524365694076 0.391688702602947 ANXA1/PLK3 2 GO:0003015 heart process 3/138 251/18722 0.28239239369949 0.391688702602947 GPX1/CXCR4/PDE4B 3 GO:0010824 regulation of centrosome duplication 1/138 45/18722 0.283457077629298 0.391688702602947 CHMP5 1 GO:0030850 prostate gland development 1/138 45/18722 0.283457077629298 0.391688702602947 ANXA1 1 GO:0035305 negative regulation of dephosphorylation 1/138 45/18722 0.283457077629298 0.391688702602947 PPP1R15A 1 GO:0035384 thioester biosynthetic process 1/138 45/18722 0.283457077629298 0.391688702602947 SNCA 1 GO:0035987 endodermal cell differentiation 1/138 45/18722 0.283457077629298 0.391688702602947 FN1 1 GO:0045933 positive regulation of muscle contraction 1/138 45/18722 0.283457077629298 0.391688702602947 PTGS2 1 GO:0046189 phenol-containing compound biosynthetic process 1/138 45/18722 0.283457077629298 0.391688702602947 SNCA 1 GO:0048546 digestive tract morphogenesis 1/138 45/18722 0.283457077629298 0.391688702602947 HIF1A 1 GO:0051180 vitamin transport 1/138 45/18722 0.283457077629298 0.391688702602947 SLC2A3 1 GO:0051985 negative regulation of chromosome segregation 1/138 45/18722 0.283457077629298 0.391688702602947 DUSP1 1 GO:0071364 cellular response to epidermal growth factor stimulus 1/138 45/18722 0.283457077629298 0.391688702602947 ZFP36 1 GO:0071616 acyl-CoA biosynthetic process 1/138 45/18722 0.283457077629298 0.391688702602947 SNCA 1 GO:1901985 positive regulation of protein acetylation 1/138 45/18722 0.283457077629298 0.391688702602947 IL1B 1 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process 1/138 45/18722 0.283457077629298 0.391688702602947 BNIP3L 1 GO:1905819 negative regulation of chromosome separation 1/138 45/18722 0.283457077629298 0.391688702602947 DUSP1 1 GO:2000273 positive regulation of signaling receptor activity 1/138 45/18722 0.283457077629298 0.391688702602947 HIF1A 1 GO:0061448 connective tissue development 3/138 252/18722 0.284395787345967 0.39279080703912 EGR1/HIF1A/UBB 3 GO:0097305 response to alcohol 3/138 253/18722 0.286400447892163 0.395337368220834 FOS/KLF2/FOSB 3 GO:0014065 phosphatidylinositol 3-kinase signaling 2/138 144/18722 0.28698173954066 0.395337368220834 FN1/OSM 2 GO:0046718 viral entry into host cell 2/138 144/18722 0.28698173954066 0.395337368220834 CXCR4/CD55 2 GO:0006195 purine nucleotide catabolic process 1/138 46/18722 0.288751446279893 0.395337368220834 PDE4B 1 GO:0006383 transcription by RNA polymerase III 1/138 46/18722 0.288751446279893 0.395337368220834 IVNS1ABP 1 GO:0007019 microtubule depolymerization 1/138 46/18722 0.288751446279893 0.395337368220834 MID1IP1 1 GO:0010828 positive regulation of glucose transmembrane transport 1/138 46/18722 0.288751446279893 0.395337368220834 IRS2 1 GO:0031018 endocrine pancreas development 1/138 46/18722 0.288751446279893 0.395337368220834 ANXA1 1 GO:0031057 negative regulation of histone modification 1/138 46/18722 0.288751446279893 0.395337368220834 SNCA 1 GO:0031294 lymphocyte costimulation 1/138 46/18722 0.288751446279893 0.395337368220834 MAP3K8 1 GO:0031648 protein destabilization 1/138 46/18722 0.288751446279893 0.395337368220834 SNCA 1 GO:0033047 regulation of mitotic sister chromatid segregation 1/138 46/18722 0.288751446279893 0.395337368220834 DUSP1 1 GO:0034198 cellular response to amino acid starvation 1/138 46/18722 0.288751446279893 0.395337368220834 FAS 1 GO:0043462 regulation of ATPase activity 1/138 46/18722 0.288751446279893 0.395337368220834 GABARAPL2 1 GO:0043616 keratinocyte proliferation 1/138 46/18722 0.288751446279893 0.395337368220834 ZFP36 1 GO:0061028 establishment of endothelial barrier 1/138 46/18722 0.288751446279893 0.395337368220834 IL1B 1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 1/138 46/18722 0.288751446279893 0.395337368220834 ANXA1 1 GO:0072503 cellular divalent inorganic cation homeostasis 5/138 486/18722 0.28879657549154 0.395337368220834 SNCA/HMGB1/CXCR4/GPR65/CD55 5 GO:0061351 neural precursor cell proliferation 2/138 145/18722 0.289708943883556 0.39639134258994 BTG2/HIF1A 2 GO:0048285 organelle fission 5/138 488/18722 0.291653350400035 0.398355120878842 DUSP1/IL1B/UBB/CHMP5/UBE2S 5 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 3/138 256/18722 0.292421398611699 0.398355120878842 FBN1/LRG1/SKIL 3 GO:0090596 sensory organ morphogenesis 3/138 256/18722 0.292421398611699 0.398355120878842 FBN1/HIF1A/HMGN1 3 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 2/138 146/18722 0.292434982958408 0.398355120878842 GPR65/PDE4B 2 GO:0009117 nucleotide metabolic process 5/138 489/18722 0.293083700564871 0.398355120878842 DDIT4/LDHA/SNCA/HIF1A/PDE4B 5 GO:0001774 microglial cell activation 1/138 47/18722 0.294006977465017 0.398355120878842 SNCA 1 GO:0007595 lactation 1/138 47/18722 0.294006977465017 0.398355120878842 HIF1A 1 GO:0009261 ribonucleotide catabolic process 1/138 47/18722 0.294006977465017 0.398355120878842 PDE4B 1 GO:0010799 regulation of peptidyl-threonine phosphorylation 1/138 47/18722 0.294006977465017 0.398355120878842 DDIT4 1 GO:0032369 negative regulation of lipid transport 1/138 47/18722 0.294006977465017 0.398355120878842 IRS2 1 GO:0045601 regulation of endothelial cell differentiation 1/138 47/18722 0.294006977465017 0.398355120878842 IL1B 1 GO:0046677 response to antibiotic 1/138 47/18722 0.294006977465017 0.398355120878842 AOC1 1 GO:0048483 autonomic nervous system development 1/138 47/18722 0.294006977465017 0.398355120878842 FN1 1 GO:0048512 circadian behavior 1/138 47/18722 0.294006977465017 0.398355120878842 EGR1 1 GO:0050798 activated T cell proliferation 1/138 47/18722 0.294006977465017 0.398355120878842 HMGB1 1 GO:0051972 regulation of telomerase activity 1/138 47/18722 0.294006977465017 0.398355120878842 HNRNPA2B1 1 GO:0097300 programmed necrotic cell death 1/138 47/18722 0.294006977465017 0.398355120878842 FAS 1 GO:0101023 vascular endothelial cell proliferation 1/138 47/18722 0.294006977465017 0.398355120878842 HMGB1 1 GO:1903170 negative regulation of calcium ion transmembrane transport 1/138 47/18722 0.294006977465017 0.398355120878842 C4orf3 1 GO:1905562 regulation of vascular endothelial cell proliferation 1/138 47/18722 0.294006977465017 0.398355120878842 HMGB1 1 GO:0060041 retina development in camera-type eye 2/138 147/18722 0.295159726579721 0.399722393708693 HIF1A/JMJD6 2 GO:1903900 regulation of viral life cycle 2/138 148/18722 0.297883046516338 0.403214259948915 CXCL8/DDX5 2 GO:0045927 positive regulation of growth 3/138 259/18722 0.298451491374208 0.403787311859223 FN1/SERP1/CXCR4 3 GO:0045839 negative regulation of mitotic nuclear division 1/138 48/18722 0.299223954017082 0.404397918785433 DUSP1 1 GO:1905710 positive regulation of membrane permeability 1/138 48/18722 0.299223954017082 0.404397918785433 BNIP3L 1 GO:0018108 peptidyl-tyrosine phosphorylation 4/138 375/18722 0.299338739740565 0.404397918785433 OSM/SAMSN1/SOCS3/MIF 4 GO:0051321 meiotic cell cycle 3/138 261/18722 0.302475811079128 0.407284900799228 DUSP1/MYH9/UBB 3 GO:0018212 peptidyl-tyrosine modification 4/138 378/18722 0.304312040141874 0.407284900799228 OSM/SAMSN1/SOCS3/MIF 4 GO:0006778 porphyrin-containing compound metabolic process 1/138 49/18722 0.304402656723821 0.407284900799228 ALAS2 1 GO:0007622 rhythmic behavior 1/138 49/18722 0.304402656723821 0.407284900799228 EGR1 1 GO:0008038 neuron recognition 1/138 49/18722 0.304402656723821 0.407284900799228 CXCR4 1 GO:0009395 phospholipid catabolic process 1/138 49/18722 0.304402656723821 0.407284900799228 PRDX6 1 GO:0010823 negative regulation of mitochondrion organization 1/138 49/18722 0.304402656723821 0.407284900799228 GPX1 1 GO:0030225 macrophage differentiation 1/138 49/18722 0.304402656723821 0.407284900799228 TRIB1 1 GO:0032692 negative regulation of interleukin-1 production 1/138 49/18722 0.304402656723821 0.407284900799228 IL1R2 1 GO:0046605 regulation of centrosome cycle 1/138 49/18722 0.304402656723821 0.407284900799228 CHMP5 1 GO:0048168 regulation of neuronal synaptic plasticity 1/138 49/18722 0.304402656723821 0.407284900799228 SNCA 1 GO:0051445 regulation of meiotic cell cycle 1/138 49/18722 0.304402656723821 0.407284900799228 DUSP1 1 GO:0052372 modulation by symbiont of entry into host 1/138 49/18722 0.304402656723821 0.407284900799228 CXCL8 1 GO:0060986 endocrine hormone secretion 1/138 49/18722 0.304402656723821 0.407284900799228 IL1B 1 GO:0070169 positive regulation of biomineral tissue development 1/138 49/18722 0.304402656723821 0.407284900799228 CEBPB 1 GO:0070849 response to epidermal growth factor 1/138 49/18722 0.304402656723821 0.407284900799228 ZFP36 1 GO:0072091 regulation of stem cell proliferation 1/138 49/18722 0.304402656723821 0.407284900799228 HMGB2 1 GO:1901799 negative regulation of proteasomal protein catabolic process 1/138 49/18722 0.304402656723821 0.407284900799228 GABARAPL2 1 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 1/138 49/18722 0.304402656723821 0.407284900799228 JUN 1 GO:1990928 response to amino acid starvation 1/138 49/18722 0.304402656723821 0.407284900799228 FAS 1 GO:0006753 nucleoside phosphate metabolic process 5/138 497/18722 0.304570500166926 0.407313648229003 DDIT4/LDHA/SNCA/HIF1A/PDE4B 5 GO:0031497 chromatin assembly 2/138 151/18722 0.306043210774098 0.408890185110088 HMGB1/HMGB2 2 GO:0071333 cellular response to glucose stimulus 2/138 151/18722 0.306043210774098 0.408890185110088 HIF1A/IRS2 2 GO:0031056 regulation of histone modification 2/138 152/18722 0.308759592003341 0.411394070184551 SNCA/IL1B 2 GO:0050871 positive regulation of B cell activation 2/138 152/18722 0.308759592003341 0.411394070184551 IRS2/MIF 2 GO:0007080 mitotic metaphase plate congression 1/138 50/18722 0.309543364342957 0.411394070184551 CHMP5 1 GO:0007140 male meiotic nuclear division 1/138 50/18722 0.309543364342957 0.411394070184551 UBB 1 GO:0007632 visual behavior 1/138 50/18722 0.309543364342957 0.411394070184551 HIF1A 1 GO:0010665 regulation of cardiac muscle cell apoptotic process 1/138 50/18722 0.309543364342957 0.411394070184551 PPP1R10 1 GO:0015872 dopamine transport 1/138 50/18722 0.309543364342957 0.411394070184551 SNCA 1 GO:0030490 maturation of SSU-rRNA 1/138 50/18722 0.309543364342957 0.411394070184551 RIOK3 1 GO:0099054 presynapse assembly 1/138 50/18722 0.309543364342957 0.411394070184551 SNCA 1 GO:0110151 positive regulation of biomineralization 1/138 50/18722 0.309543364342957 0.411394070184551 CEBPB 1 GO:1903747 regulation of establishment of protein localization to mitochondrion 1/138 50/18722 0.309543364342957 0.411394070184551 BNIP3L 1 GO:0071331 cellular response to hexose stimulus 2/138 153/18722 0.311473936966249 0.413762275215785 HIF1A/IRS2 2 GO:0050770 regulation of axonogenesis 2/138 154/18722 0.314186128715973 0.415005119486008 FN1/SKIL 2 GO:0051168 nuclear export 2/138 154/18722 0.314186128715973 0.415005119486008 IL1B/HNRNPA2B1 2 GO:0071326 cellular response to monosaccharide stimulus 2/138 154/18722 0.314186128715973 0.415005119486008 HIF1A/IRS2 2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone 1/138 51/18722 0.314646353616772 0.415005119486008 SNCA 1 GO:0009948 anterior/posterior axis specification 1/138 51/18722 0.314646353616772 0.415005119486008 ETS2 1 GO:0010656 negative regulation of muscle cell apoptotic process 1/138 51/18722 0.314646353616772 0.415005119486008 PPP1R10 1 GO:0010874 regulation of cholesterol efflux 1/138 51/18722 0.314646353616772 0.415005119486008 NFKBIA 1 GO:0014009 glial cell proliferation 1/138 51/18722 0.314646353616772 0.415005119486008 IL1B 1 GO:0021872 forebrain generation of neurons 1/138 51/18722 0.314646353616772 0.415005119486008 UBB 1 GO:0032873 negative regulation of stress-activated MAPK cascade 1/138 51/18722 0.314646353616772 0.415005119486008 DUSP1 1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 1/138 51/18722 0.314646353616772 0.415005119486008 RIOK3 1 GO:0050982 detection of mechanical stimulus 1/138 51/18722 0.314646353616772 0.415005119486008 CXCR4 1 GO:0051293 establishment of spindle localization 1/138 51/18722 0.314646353616772 0.415005119486008 MYH9 1 GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 1/138 51/18722 0.314646353616772 0.415005119486008 DUSP1 1 GO:0071622 regulation of granulocyte chemotaxis 1/138 51/18722 0.314646353616772 0.415005119486008 CXCL8 1 GO:0010970 transport along microtubule 2/138 155/18722 0.316896052114638 0.417378946064854 HIF1A/UBB 2 GO:0046434 organophosphate catabolic process 2/138 155/18722 0.316896052114638 0.417378946064854 PDE4B/PRDX6 2 GO:1903364 positive regulation of cellular protein catabolic process 2/138 155/18722 0.316896052114638 0.417378946064854 TRIB1/PLK3 2 GO:0045860 positive regulation of protein kinase activity 4/138 386/18722 0.317618095186076 0.418132052461139 EGR1/SNCA/HMGB1/IL1B 4 GO:0002218 activation of innate immune response 1/138 52/18722 0.319711899286574 0.419499394490587 HMGB1 1 GO:0010662 regulation of striated muscle cell apoptotic process 1/138 52/18722 0.319711899286574 0.419499394490587 PPP1R10 1 GO:0010718 positive regulation of epithelial to mesenchymal transition 1/138 52/18722 0.319711899286574 0.419499394490587 IL1B 1 GO:0051496 positive regulation of stress fiber assembly 1/138 52/18722 0.319711899286574 0.419499394490587 GPR65 1 GO:0072523 purine-containing compound catabolic process 1/138 52/18722 0.319711899286574 0.419499394490587 PDE4B 1 GO:1903426 regulation of reactive oxygen species biosynthetic process 1/138 52/18722 0.319711899286574 0.419499394490587 SNCA 1 GO:2000378 negative regulation of reactive oxygen species metabolic process 1/138 52/18722 0.319711899286574 0.419499394490587 HIF1A 1 GO:0007034 vacuolar transport 2/138 157/18722 0.322308642232495 0.422508220128607 CHMP5/RHOB 2 GO:2000377 regulation of reactive oxygen species metabolic process 2/138 157/18722 0.322308642232495 0.422508220128607 SNCA/HIF1A 2 GO:1901987 regulation of cell cycle phase transition 4/138 390/18722 0.324290928118029 0.423898772438999 DUSP1/PPP1R10/ANXA1/PLK3 4 GO:0001541 ovarian follicle development 1/138 53/18722 0.324740274107059 0.423898772438999 CEBPB 1 GO:0002707 negative regulation of lymphocyte mediated immunity 1/138 53/18722 0.324740274107059 0.423898772438999 CD55 1 GO:0016925 protein sumoylation 1/138 53/18722 0.324740274107059 0.423898772438999 EGR1 1 GO:0032784 regulation of DNA-templated transcription, elongation 1/138 53/18722 0.324740274107059 0.423898772438999 HMGN1 1 GO:0051438 regulation of ubiquitin-protein transferase activity 1/138 53/18722 0.324740274107059 0.423898772438999 UBE2S 1 GO:0097479 synaptic vesicle localization 1/138 53/18722 0.324740274107059 0.423898772438999 SNCA 1 GO:0099172 presynapse organization 1/138 53/18722 0.324740274107059 0.423898772438999 SNCA 1 GO:2000772 regulation of cellular senescence 1/138 53/18722 0.324740274107059 0.423898772438999 YBX1 1 GO:0034249 negative regulation of cellular amide metabolic process 3/138 273/18722 0.326664886640104 0.42601142432962 BTG2/ZFP36/YBX1 3 GO:0046942 carboxylic acid transport 3/138 273/18722 0.326664886640104 0.42601142432962 SNCA/IL1B/ANXA1 3 GO:0046486 glycerolipid metabolic process 4/138 392/18722 0.327631342251612 0.426775487426186 PLEK/GPX1/SOCS3/PRDX6 4 GO:0032200 telomere organization 2/138 159/18722 0.327710821642026 0.426775487426186 PPP1R10/HNRNPA2B1 2 GO:0046488 phosphatidylinositol metabolic process 2/138 159/18722 0.327710821642026 0.426775487426186 PLEK/SOCS3 2 GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1/138 54/18722 0.329731748860566 0.427606457166335 CD55 1 GO:0006584 catecholamine metabolic process 1/138 54/18722 0.329731748860566 0.427606457166335 SNCA 1 GO:0006968 cellular defense response 1/138 54/18722 0.329731748860566 0.427606457166335 LSP1 1 GO:0009712 catechol-containing compound metabolic process 1/138 54/18722 0.329731748860566 0.427606457166335 SNCA 1 GO:0010524 positive regulation of calcium ion transport into cytosol 1/138 54/18722 0.329731748860566 0.427606457166335 SNCA 1 GO:0010659 cardiac muscle cell apoptotic process 1/138 54/18722 0.329731748860566 0.427606457166335 PPP1R10 1 GO:0030520 intracellular estrogen receptor signaling pathway 1/138 54/18722 0.329731748860566 0.427606457166335 DDX5 1 GO:0030834 regulation of actin filament depolymerization 1/138 54/18722 0.329731748860566 0.427606457166335 PLEK 1 GO:2000179 positive regulation of neural precursor cell proliferation 1/138 54/18722 0.329731748860566 0.427606457166335 HIF1A 1 GO:0043270 positive regulation of ion transport 3/138 275/18722 0.330699281777257 0.428661435112299 CEBPB/SNCA/IL1B 3 GO:0034470 ncRNA processing 4/138 395/18722 0.33264620660076 0.430874663533795 RIOK3/DDX21/HNRNPA2B1/RPL7 4 GO:0007548 sex differentiation 3/138 276/18722 0.332716367924587 0.430874663533795 CEBPB/UBB/HMGB2 3 GO:0000768 syncytium formation by plasma membrane fusion 1/138 55/18722 0.334686592371239 0.432279718772961 MYH9 1 GO:0031113 regulation of microtubule polymerization 1/138 55/18722 0.334686592371239 0.432279718772961 SNCA 1 GO:0042220 response to cocaine 1/138 55/18722 0.334686592371239 0.432279718772961 SNCA 1 GO:0140253 cell-cell fusion 1/138 55/18722 0.334686592371239 0.432279718772961 MYH9 1 GO:1905517 macrophage migration 1/138 55/18722 0.334686592371239 0.432279718772961 MIF 1 GO:0110053 regulation of actin filament organization 3/138 277/18722 0.334733307206515 0.432279718772961 PLEK/ACTG1/GPR65 3 GO:0021953 central nervous system neuron differentiation 2/138 162/18722 0.335792701238434 0.433245752223718 BTG2/UBB 2 GO:0051494 negative regulation of cytoskeleton organization 2/138 162/18722 0.335792701238434 0.433245752223718 SNCA/MID1IP1 2 GO:0022898 regulation of transmembrane transporter activity 3/138 278/18722 0.336750045684217 0.434279600157171 SNCA/C4orf3/PDE4B 3 GO:0061025 membrane fusion 2/138 163/18722 0.338480543438371 0.435338974683373 SNCA/ANXA1 2 GO:0071322 cellular response to carbohydrate stimulus 2/138 163/18722 0.338480543438371 0.435338974683373 HIF1A/IRS2 2 GO:0002886 regulation of myeloid leukocyte mediated immunity 1/138 56/18722 0.339605071519081 0.435338974683373 DDX21 1 GO:0010658 striated muscle cell apoptotic process 1/138 56/18722 0.339605071519081 0.435338974683373 PPP1R10 1 GO:0015800 acidic amino acid transport 1/138 56/18722 0.339605071519081 0.435338974683373 SNCA 1 GO:0022029 telencephalon cell migration 1/138 56/18722 0.339605071519081 0.435338974683373 CXCR4 1 GO:0031122 cytoplasmic microtubule organization 1/138 56/18722 0.339605071519081 0.435338974683373 PLK3 1 GO:0031529 ruffle organization 1/138 56/18722 0.339605071519081 0.435338974683373 PLEK 1 GO:0046622 positive regulation of organ growth 1/138 56/18722 0.339605071519081 0.435338974683373 SERP1 1 GO:0050433 regulation of catecholamine secretion 1/138 56/18722 0.339605071519081 0.435338974683373 SNCA 1 GO:0051653 spindle localization 1/138 56/18722 0.339605071519081 0.435338974683373 MYH9 1 GO:0051784 negative regulation of nuclear division 1/138 56/18722 0.339605071519081 0.435338974683373 DUSP1 1 GO:0070534 protein K63-linked ubiquitination 1/138 56/18722 0.339605071519081 0.435338974683373 UBE2S 1 GO:0021700 developmental maturation 3/138 280/18722 0.340782706470011 0.436647454929116 KLF2/HIF1A/FAM210B 3 GO:0050806 positive regulation of synaptic transmission 2/138 164/18722 0.341165159217099 0.436735344112781 PTGS2/SNCA 2 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 2/138 164/18722 0.341165159217099 0.436735344112781 TRIB1/PLK3 2 GO:0046661 male sex differentiation 2/138 165/18722 0.343846450459088 0.439572937569757 UBB/HMGB2 2 GO:0006611 protein export from nucleus 1/138 57/18722 0.344487451253913 0.439572937569757 IL1B 1 GO:0006695 cholesterol biosynthetic process 1/138 57/18722 0.344487451253913 0.439572937569757 IDI1 1 GO:0006949 syncytium formation 1/138 57/18722 0.344487451253913 0.439572937569757 MYH9 1 GO:0030219 megakaryocyte differentiation 1/138 57/18722 0.344487451253913 0.439572937569757 HMGB2 1 GO:0051785 positive regulation of nuclear division 1/138 57/18722 0.344487451253913 0.439572937569757 IL1B 1 GO:1902653 secondary alcohol biosynthetic process 1/138 57/18722 0.344487451253913 0.439572937569757 IDI1 1 GO:0030307 positive regulation of cell growth 2/138 166/18722 0.346524320648377 0.44176691908586 FN1/CXCR4 2 GO:1902904 negative regulation of supramolecular fiber organization 2/138 166/18722 0.346524320648377 0.44176691908586 SNCA/MID1IP1 2 GO:0002931 response to ischemia 1/138 58/18722 0.349333994609228 0.443925345660951 EGR1 1 GO:0006826 iron ion transport 1/138 58/18722 0.349333994609228 0.443925345660951 FTH1 1 GO:0007405 neuroblast proliferation 1/138 58/18722 0.349333994609228 0.443925345660951 HIF1A 1 GO:0045604 regulation of epidermal cell differentiation 1/138 58/18722 0.349333994609228 0.443925345660951 ZFP36 1 GO:0050432 catecholamine secretion 1/138 58/18722 0.349333994609228 0.443925345660951 SNCA 1 GO:1902808 positive regulation of cell cycle G1/S phase transition 1/138 58/18722 0.349333994609228 0.443925345660951 ANXA1 1 GO:2000736 regulation of stem cell differentiation 1/138 58/18722 0.349333994609228 0.443925345660951 OSM 1 GO:0000070 mitotic sister chromatid segregation 2/138 168/18722 0.35186941969534 0.446332085237982 DUSP1/CHMP5 2 GO:0099173 postsynapse organization 2/138 168/18722 0.35186941969534 0.446332085237982 ACTG1/SRGN 2 GO:1902806 regulation of cell cycle G1/S phase transition 2/138 168/18722 0.35186941969534 0.446332085237982 ANXA1/PLK3 2 GO:2000241 regulation of reproductive process 2/138 168/18722 0.35186941969534 0.446332085237982 DUSP1/MYH9 2 GO:0006406 mRNA export from nucleus 1/138 59/18722 0.354144962715954 0.447180322703493 HNRNPA2B1 1 GO:0006767 water-soluble vitamin metabolic process 1/138 59/18722 0.354144962715954 0.447180322703493 SLC2A3 1 GO:0021885 forebrain cell migration 1/138 59/18722 0.354144962715954 0.447180322703493 CXCR4 1 GO:0030042 actin filament depolymerization 1/138 59/18722 0.354144962715954 0.447180322703493 PLEK 1 GO:0033013 tetrapyrrole metabolic process 1/138 59/18722 0.354144962715954 0.447180322703493 ALAS2 1 GO:0043551 regulation of phosphatidylinositol 3-kinase activity 1/138 59/18722 0.354144962715954 0.447180322703493 SOCS3 1 GO:0046324 regulation of glucose import 1/138 59/18722 0.354144962715954 0.447180322703493 IRS2 1 GO:0048278 vesicle docking 1/138 59/18722 0.354144962715954 0.447180322703493 PLEK 1 GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus 1/138 59/18722 0.354144962715954 0.447180322703493 HNRNPA2B1 1 GO:0071806 protein transmembrane transport 1/138 59/18722 0.354144962715954 0.447180322703493 MCL1 1 GO:0006937 regulation of muscle contraction 2/138 169/18722 0.354536463358277 0.447471645136546 PTGS2/PDE4B 2 GO:0002712 regulation of B cell mediated immunity 1/138 60/18722 0.358920614816109 0.451367406702771 CD55 1 GO:0002889 regulation of immunoglobulin mediated immune response 1/138 60/18722 0.358920614816109 0.451367406702771 CD55 1 GO:0030071 regulation of mitotic metaphase/anaphase transition 1/138 60/18722 0.358920614816109 0.451367406702771 DUSP1 1 GO:0033866 nucleoside bisphosphate biosynthetic process 1/138 60/18722 0.358920614816109 0.451367406702771 SNCA 1 GO:0034030 ribonucleoside bisphosphate biosynthetic process 1/138 60/18722 0.358920614816109 0.451367406702771 SNCA 1 GO:0034033 purine nucleoside bisphosphate biosynthetic process 1/138 60/18722 0.358920614816109 0.451367406702771 SNCA 1 GO:0042306 regulation of protein import into nucleus 1/138 60/18722 0.358920614816109 0.451367406702771 PTGS2 1 GO:0051851 modulation by host of symbiont process 1/138 60/18722 0.358920614816109 0.451367406702771 JUN 1 GO:0001678 cellular glucose homeostasis 2/138 172/18722 0.362514491842842 0.455269779241259 HIF1A/IRS2 2 GO:0007219 Notch signaling pathway 2/138 172/18722 0.362514491842842 0.455269779241259 NFKBIA/KRT19 2 GO:1990138 neuron projection extension 2/138 172/18722 0.362514491842842 0.455269779241259 FN1/CXCR4 2 GO:0016236 macroautophagy 3/138 291/18722 0.362925557434385 0.455580435877264 BNIP3L/GABARAPL2/HIF1A 3 GO:0006900 vesicle budding from membrane 1/138 61/18722 0.363661208276369 0.455681739141439 CHMP5 1 GO:0034113 heterotypic cell-cell adhesion 1/138 61/18722 0.363661208276369 0.455681739141439 IL1B 1 GO:0043966 histone H3 acetylation 1/138 61/18722 0.363661208276369 0.455681739141439 TAF10 1 GO:1904356 regulation of telomere maintenance via telomere lengthening 1/138 61/18722 0.363661208276369 0.455681739141439 HNRNPA2B1 1 GO:0006694 steroid biosynthetic process 2/138 173/18722 0.365165842854692 0.457361179417016 EGR1/IDI1 2 GO:0001822 kidney development 3/138 293/18722 0.36694156981514 0.45937849248562 EGR1/FBN1/JMJD6 3 GO:0007091 metaphase/anaphase transition of mitotic cell cycle 1/138 62/18722 0.368366998601532 0.459715406774917 DUSP1 1 GO:0032615 interleukin-12 production 1/138 62/18722 0.368366998601532 0.459715406774917 HMGB1 1 GO:0032655 regulation of interleukin-12 production 1/138 62/18722 0.368366998601532 0.459715406774917 HMGB1 1 GO:0032835 glomerulus development 1/138 62/18722 0.368366998601532 0.459715406774917 EGR1 1 GO:0046148 pigment biosynthetic process 1/138 62/18722 0.368366998601532 0.459715406774917 ALAS2 1 GO:0046847 filopodium assembly 1/138 62/18722 0.368366998601532 0.459715406774917 FGD3 1 GO:0070265 necrotic cell death 1/138 62/18722 0.368366998601532 0.459715406774917 FAS 1 GO:0010948 negative regulation of cell cycle process 3/138 294/18722 0.368948085398751 0.460234209621123 DUSP1/PPP1R10/PLK3 3 GO:0022900 electron transport chain 2/138 175/18722 0.370456048831313 0.461701381055774 SNCA/UQCRH 2 GO:0050954 sensory perception of mechanical stimulus 2/138 175/18722 0.370456048831313 0.461701381055774 GPX1/CXCR4 2 GO:0051258 protein polymerization 3/138 296/18722 0.372957899466422 0.463673702717048 SNCA/MID1IP1/UBE2S 3 GO:0001947 heart looping 1/138 63/18722 0.373038239447887 0.463673702717048 HIF1A 1 GO:0002704 negative regulation of leukocyte mediated immunity 1/138 63/18722 0.373038239447887 0.463673702717048 CD55 1 GO:0046902 regulation of mitochondrial membrane permeability 1/138 63/18722 0.373038239447887 0.463673702717048 BNIP3L 1 GO:1902099 regulation of metaphase/anaphase transition of cell cycle 1/138 63/18722 0.373038239447887 0.463673702717048 DUSP1 1 GO:1904589 regulation of protein import 1/138 63/18722 0.373038239447887 0.463673702717048 PTGS2 1 GO:0006333 chromatin assembly or disassembly 2/138 177/18722 0.375729047821819 0.466601490445392 HMGB1/HMGB2 2 GO:0098739 import across plasma membrane 2/138 177/18722 0.375729047821819 0.466601490445392 SLC2A3/IRS2 2 GO:0006749 glutathione metabolic process 1/138 64/18722 0.377675182636493 0.466727368240391 GPX1 1 GO:0006940 regulation of smooth muscle contraction 1/138 64/18722 0.377675182636493 0.466727368240391 PTGS2 1 GO:0016126 sterol biosynthetic process 1/138 64/18722 0.377675182636493 0.466727368240391 IDI1 1 GO:0017156 calcium-ion regulated exocytosis 1/138 64/18722 0.377675182636493 0.466727368240391 MYH9 1 GO:0046579 positive regulation of Ras protein signal transduction 1/138 64/18722 0.377675182636493 0.466727368240391 GPR65 1 GO:0046854 phosphatidylinositol phosphate biosynthetic process 1/138 64/18722 0.377675182636493 0.466727368240391 SOCS3 1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 1/138 64/18722 0.377675182636493 0.466727368240391 HIF1A 1 GO:0070542 response to fatty acid 1/138 64/18722 0.377675182636493 0.466727368240391 PTGS2 1 GO:0098930 axonal transport 1/138 64/18722 0.377675182636493 0.466727368240391 HIF1A 1 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process 1/138 64/18722 0.377675182636493 0.466727368240391 GABARAPL2 1 GO:1903409 reactive oxygen species biosynthetic process 1/138 64/18722 0.377675182636493 0.466727368240391 SNCA 1 GO:0048015 phosphatidylinositol-mediated signaling 2/138 178/18722 0.37835889539426 0.467364760711152 FN1/OSM 2 GO:0042254 ribosome biogenesis 3/138 299/18722 0.378963881961358 0.467696888469384 RIOK3/DDX21/RPL7 3 GO:1901990 regulation of mitotic cell cycle phase transition 3/138 299/18722 0.378963881961358 0.467696888469384 DUSP1/ANXA1/PLK3 3 GO:0006941 striated muscle contraction 2/138 179/18722 0.380984204834565 0.469496862990717 CXCR4/PDE4B 2 GO:0007626 locomotory behavior 2/138 179/18722 0.380984204834565 0.469496862990717 EGR1/SNCA 2 GO:1901991 negative regulation of mitotic cell cycle phase transition 2/138 179/18722 0.380984204834565 0.469496862990717 DUSP1/PLK3 2 GO:0010965 regulation of mitotic sister chromatid separation 1/138 65/18722 0.382278078166355 0.469496862990717 DUSP1 1 GO:0033692 cellular polysaccharide biosynthetic process 1/138 65/18722 0.382278078166355 0.469496862990717 IRS2 1 GO:0044784 metaphase/anaphase transition of cell cycle 1/138 65/18722 0.382278078166355 0.469496862990717 DUSP1 1 GO:0045682 regulation of epidermis development 1/138 65/18722 0.382278078166355 0.469496862990717 ZFP36 1 GO:0046503 glycerolipid catabolic process 1/138 65/18722 0.382278078166355 0.469496862990717 PRDX6 1 GO:0051310 metaphase plate congression 1/138 65/18722 0.382278078166355 0.469496862990717 CHMP5 1 GO:0071677 positive regulation of mononuclear cell migration 1/138 65/18722 0.382278078166355 0.469496862990717 HMGB1 1 GO:0090307 mitotic spindle assembly 1/138 65/18722 0.382278078166355 0.469496862990717 CHMP5 1 GO:0042063 gliogenesis 3/138 301/18722 0.382961512476957 0.470128755722705 CXCR4/IL1B/ANXA1 3 GO:0007033 vacuole organization 2/138 180/18722 0.383604900213516 0.470296227882915 GABARAPL2/CHMP5 2 GO:0010721 negative regulation of cell development 2/138 180/18722 0.383604900213516 0.470296227882915 FBN1/IL1B 2 GO:0071897 DNA biosynthetic process 2/138 180/18722 0.383604900213516 0.470296227882915 DUSP1/HNRNPA2B1 2 GO:0072001 renal system development 3/138 302/18722 0.384958285914579 0.471747648480966 EGR1/FBN1/JMJD6 3 GO:0008361 regulation of cell size 2/138 181/18722 0.386220906949876 0.472398282525305 FN1/PLEK 2 GO:0099504 synaptic vesicle cycle 2/138 181/18722 0.386220906949876 0.472398282525305 SNCA/ACTG1 2 GO:0043254 regulation of protein-containing complex assembly 4/138 427/18722 0.386233293369427 0.472398282525305 PLEK/SNCA/HMGB1/RIOK3 4 GO:0019229 regulation of vasoconstriction 1/138 66/18722 0.386847174227514 0.472398282525305 PTGS2 1 GO:0032715 negative regulation of interleukin-6 production 1/138 66/18722 0.386847174227514 0.472398282525305 KLF2 1 GO:0050766 positive regulation of phagocytosis 1/138 66/18722 0.386847174227514 0.472398282525305 IL1B 1 GO:0051893 regulation of focal adhesion assembly 1/138 66/18722 0.386847174227514 0.472398282525305 ACTG1 1 GO:0090109 regulation of cell-substrate junction assembly 1/138 66/18722 0.386847174227514 0.472398282525305 ACTG1 1 GO:0048017 inositol lipid-mediated signaling 2/138 182/18722 0.388832151794894 0.474405909007098 FN1/OSM 2 GO:0051260 protein homooligomerization 2/138 182/18722 0.388832151794894 0.474405909007098 JMJD6/MIF 2 GO:0006513 protein monoubiquitination 1/138 67/18722 0.391382717214039 0.476473360457861 UBB 1 GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 1/138 67/18722 0.391382717214039 0.476473360457861 ANXA1 1 GO:0042130 negative regulation of T cell proliferation 1/138 67/18722 0.391382717214039 0.476473360457861 CEBPB 1 GO:0051306 mitotic sister chromatid separation 1/138 67/18722 0.391382717214039 0.476473360457861 DUSP1 1 GO:0061371 determination of heart left/right asymmetry 1/138 67/18722 0.391382717214039 0.476473360457861 HIF1A 1 GO:0006650 glycerophospholipid metabolic process 3/138 306/18722 0.392930744282488 0.478148780646333 PLEK/SOCS3/PRDX6 3 GO:0007051 spindle organization 2/138 184/18722 0.394040069386498 0.479289122859538 MYH9/CHMP5 2 GO:0031640 killing of cells of other organism 1/138 68/18722 0.395884951736926 0.48048313156732 TREM1 1 GO:0032922 circadian regulation of gene expression 1/138 68/18722 0.395884951736926 0.48048313156732 EGR1 1 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 1/138 68/18722 0.395884951736926 0.48048313156732 OSM 1 GO:0042698 ovulation cycle 1/138 68/18722 0.395884951736926 0.48048313156732 EGR1 1 GO:0051148 negative regulation of muscle cell differentiation 1/138 68/18722 0.395884951736926 0.48048313156732 YBX1 1 GO:0051896 regulation of protein kinase B signaling 2/138 185/18722 0.396636602160763 0.481185555280473 OSM/GPX1 2 GO:0042391 regulation of membrane potential 4/138 434/18722 0.397920411395364 0.482532681879433 BNIP3L/SNCA/JUN/UBB 4 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 2/138 186/18722 0.399228093069124 0.483907570997984 DDX21/REL 2 GO:0003143 embryonic heart tube morphogenesis 1/138 69/18722 0.40035412063691 0.484007609788236 HIF1A 1 GO:0033344 cholesterol efflux 1/138 69/18722 0.40035412063691 0.484007609788236 NFKBIA 1 GO:0034605 cellular response to heat 1/138 69/18722 0.40035412063691 0.484007609788236 PTGS2 1 GO:0050688 regulation of defense response to virus 1/138 69/18722 0.40035412063691 0.484007609788236 RIOK3 1 GO:0050810 regulation of steroid biosynthetic process 1/138 69/18722 0.40035412063691 0.484007609788236 EGR1 1 GO:0051966 regulation of synaptic transmission, glutamatergic 1/138 69/18722 0.40035412063691 0.484007609788236 PTGS2 1 GO:0001906 cell killing 2/138 188/18722 0.404395683277454 0.488681366287952 TREM1/CD55 2 GO:0019932 second-messenger-mediated signaling 3/138 312/18722 0.404840839766276 0.48879481868527 CXCL8/PLEK/CXCR4 3 GO:0070588 calcium ion transmembrane transport 3/138 312/18722 0.404840839766276 0.48879481868527 SNCA/C4orf3/PDE4B 3 GO:0050804 modulation of chemical synaptic transmission 4/138 439/18722 0.406248014428777 0.49028110327636 PTGS2/SNCA/SRGN/IL1B 4 GO:0045787 positive regulation of cell cycle 3/138 313/18722 0.406819654670374 0.490758170328413 PPP1R10/IL1B/ANXA1 3 GO:0099177 regulation of trans-synaptic signaling 4/138 440/18722 0.407911150649883 0.491861669089526 PTGS2/SNCA/SRGN/IL1B 4 GO:0060249 anatomical structure homeostasis 3/138 314/18722 0.40879659037051 0.492129440720034 PTGS2/ACTG1/HIF1A 3 GO:0003208 cardiac ventricle morphogenesis 1/138 71/18722 0.409194224156003 0.492129440720034 HIF1A 1 GO:0008344 adult locomotory behavior 1/138 71/18722 0.409194224156003 0.492129440720034 SNCA 1 GO:0043550 regulation of lipid kinase activity 1/138 71/18722 0.409194224156003 0.492129440720034 SOCS3 1 GO:0071230 cellular response to amino acid stimulus 1/138 71/18722 0.409194224156003 0.492129440720034 CEBPB 1 GO:0150116 regulation of cell-substrate junction organization 1/138 71/18722 0.409194224156003 0.492129440720034 ACTG1 1 GO:0099111 microtubule-based transport 2/138 190/18722 0.409542320330655 0.492335325045449 HIF1A/UBB 2 GO:0050821 protein stabilization 2/138 191/18722 0.412107624347555 0.49520531889432 AHSP/MORC3 2 GO:0000271 polysaccharide biosynthetic process 1/138 72/18722 0.41356563571927 0.495246628316148 IRS2 1 GO:0033045 regulation of sister chromatid segregation 1/138 72/18722 0.41356563571927 0.495246628316148 DUSP1 1 GO:0033627 cell adhesion mediated by integrin 1/138 72/18722 0.41356563571927 0.495246628316148 FBN1 1 GO:0042273 ribosomal large subunit biogenesis 1/138 72/18722 0.41356563571927 0.495246628316148 RPL7 1 GO:0043903 regulation of biological process involved in symbiotic interaction 1/138 72/18722 0.41356563571927 0.495246628316148 CXCL8 1 GO:0051057 positive regulation of small GTPase mediated signal transduction 1/138 72/18722 0.41356563571927 0.495246628316148 GPR65 1 GO:1901880 negative regulation of protein depolymerization 1/138 72/18722 0.41356563571927 0.495246628316148 MID1IP1 1 GO:1905818 regulation of chromosome separation 1/138 72/18722 0.41356563571927 0.495246628316148 DUSP1 1 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 2/138 193/18722 0.4172218996336 0.497659150919752 OSM/MIF 2 GO:0009166 nucleotide catabolic process 1/138 73/18722 0.417904935572929 0.497659150919752 PDE4B 1 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 1/138 73/18722 0.417904935572929 0.497659150919752 HIF1A 1 GO:0042058 regulation of epidermal growth factor receptor signaling pathway 1/138 73/18722 0.417904935572929 0.497659150919752 PLAUR 1 GO:0042274 ribosomal small subunit biogenesis 1/138 73/18722 0.417904935572929 0.497659150919752 RIOK3 1 GO:0045739 positive regulation of DNA repair 1/138 73/18722 0.417904935572929 0.497659150919752 HMGB1 1 GO:0050848 regulation of calcium-mediated signaling 1/138 73/18722 0.417904935572929 0.497659150919752 PLEK 1 GO:0051298 centrosome duplication 1/138 73/18722 0.417904935572929 0.497659150919752 CHMP5 1 GO:0051937 catecholamine transport 1/138 73/18722 0.417904935572929 0.497659150919752 SNCA 1 GO:0070988 demethylation 1/138 73/18722 0.417904935572929 0.497659150919752 JMJD6 1 GO:0072089 stem cell proliferation 1/138 73/18722 0.417904935572929 0.497659150919752 HMGB2 1 GO:0086003 cardiac muscle cell contraction 1/138 73/18722 0.417904935572929 0.497659150919752 PDE4B 1 GO:1904427 positive regulation of calcium ion transmembrane transport 1/138 73/18722 0.417904935572929 0.497659150919752 SNCA 1 GO:0016042 lipid catabolic process 3/138 320/18722 0.420616557911954 0.500674029370817 IL1B/PRDX6/IRS2 3 GO:0003151 outflow tract morphogenesis 1/138 74/18722 0.422212357895356 0.501193978786781 HIF1A 1 GO:0006635 fatty acid beta-oxidation 1/138 74/18722 0.422212357895356 0.501193978786781 IRS2 1 GO:0007040 lysosome organization 1/138 74/18722 0.422212357895356 0.501193978786781 CHMP5 1 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 1/138 74/18722 0.422212357895356 0.501193978786781 DDX5 1 GO:0080171 lytic vacuole organization 1/138 74/18722 0.422212357895356 0.501193978786781 CHMP5 1 GO:0120192 tight junction assembly 1/138 74/18722 0.422212357895356 0.501193978786781 ACTG1 1 GO:0030705 cytoskeleton-dependent intracellular transport 2/138 195/18722 0.422314006559468 0.501193978786781 HIF1A/UBB 2 GO:0006024 glycosaminoglycan biosynthetic process 1/138 75/18722 0.426488135169617 0.50507084262853 IL1B 1 GO:0008088 axo-dendritic transport 1/138 75/18722 0.426488135169617 0.50507084262853 HIF1A 1 GO:0034121 regulation of toll-like receptor signaling pathway 1/138 75/18722 0.426488135169617 0.50507084262853 HMGB1 1 GO:0048662 negative regulation of smooth muscle cell proliferation 1/138 75/18722 0.426488135169617 0.50507084262853 TRIB1 1 GO:1903363 negative regulation of cellular protein catabolic process 1/138 75/18722 0.426488135169617 0.50507084262853 GABARAPL2 1 GO:0008544 epidermis development 3/138 324/18722 0.428454095585057 0.507183219061341 ZFP36/YBX1/ANXA1 3 GO:0048167 regulation of synaptic plasticity 2/138 198/18722 0.429909613815564 0.507720687199711 PTGS2/SNCA 2 GO:0060562 epithelial tube morphogenesis 3/138 325/18722 0.430407837928173 0.507720687199711 CXCR4/HIF1A/RHOB 3 GO:0006305 DNA alkylation 1/138 76/18722 0.430732498195659 0.507720687199711 FOS 1 GO:0006306 DNA methylation 1/138 76/18722 0.430732498195659 0.507720687199711 FOS 1 GO:0021536 diencephalon development 1/138 76/18722 0.430732498195659 0.507720687199711 UBB 1 GO:0031100 animal organ regeneration 1/138 76/18722 0.430732498195659 0.507720687199711 CEBPB 1 GO:0032720 negative regulation of tumor necrosis factor production 1/138 76/18722 0.430732498195659 0.507720687199711 BCL3 1 GO:0045685 regulation of glial cell differentiation 1/138 76/18722 0.430732498195659 0.507720687199711 CXCR4 1 GO:0071426 ribonucleoprotein complex export from nucleus 1/138 76/18722 0.430732498195659 0.507720687199711 HNRNPA2B1 1 GO:2000379 positive regulation of reactive oxygen species metabolic process 1/138 76/18722 0.430732498195659 0.507720687199711 SNCA 1 GO:0006323 DNA packaging 2/138 199/18722 0.432429918615218 0.509505700044941 HMGB1/HMGB2 2 GO:0071902 positive regulation of protein serine/threonine kinase activity 2/138 200/18722 0.434944354128885 0.510740007001251 SNCA/IL1B 2 GO:0099003 vesicle-mediated transport in synapse 2/138 200/18722 0.434944354128885 0.510740007001251 SNCA/ACTG1 2 GO:0031016 pancreas development 1/138 77/18722 0.434945676102395 0.510740007001251 ANXA1 1 GO:0032418 lysosome localization 1/138 77/18722 0.434945676102395 0.510740007001251 MYH9 1 GO:0048644 muscle organ morphogenesis 1/138 77/18722 0.434945676102395 0.510740007001251 SERP1 1 GO:0055117 regulation of cardiac muscle contraction 1/138 77/18722 0.434945676102395 0.510740007001251 PDE4B 1 GO:0071166 ribonucleoprotein complex localization 1/138 77/18722 0.434945676102395 0.510740007001251 HNRNPA2B1 1 GO:0140056 organelle localization by membrane tethering 1/138 77/18722 0.434945676102395 0.510740007001251 PLEK 1 GO:0009952 anterior/posterior pattern specification 2/138 201/18722 0.437452869676838 0.513250984953895 BTG2/ETS2 2 GO:0065004 protein-DNA complex assembly 2/138 201/18722 0.437452869676838 0.513250984953895 HMGB1/HMGB2 2 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 1/138 78/18722 0.439127896359722 0.513268767563674 SNCA 1 GO:0032371 regulation of sterol transport 1/138 78/18722 0.439127896359722 0.513268767563674 NFKBIA 1 GO:0032374 regulation of cholesterol transport 1/138 78/18722 0.439127896359722 0.513268767563674 NFKBIA 1 GO:0034637 cellular carbohydrate biosynthetic process 1/138 78/18722 0.439127896359722 0.513268767563674 IRS2 1 GO:0035050 embryonic heart tube development 1/138 78/18722 0.439127896359722 0.513268767563674 HIF1A 1 GO:0043537 negative regulation of blood vessel endothelial cell migration 1/138 78/18722 0.439127896359722 0.513268767563674 HMGB1 1 GO:0070373 negative regulation of ERK1 and ERK2 cascade 1/138 78/18722 0.439127896359722 0.513268767563674 DUSP1 1 GO:0090559 regulation of membrane permeability 1/138 78/18722 0.439127896359722 0.513268767563674 BNIP3L 1 GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 1/138 78/18722 0.439127896359722 0.513268767563674 BCL3 1 GO:0000819 sister chromatid segregation 2/138 202/18722 0.439955415632286 0.513373552077423 DUSP1/CHMP5 2 GO:0009913 epidermal cell differentiation 2/138 202/18722 0.439955415632286 0.513373552077423 ZFP36/ANXA1 2 GO:0017157 regulation of exocytosis 2/138 202/18722 0.439955415632286 0.513373552077423 SNCA/ANXA1 2 GO:1903046 meiotic cell cycle process 2/138 202/18722 0.439955415632286 0.513373552077423 MYH9/UBB 2 GO:0048638 regulation of developmental growth 3/138 330/18722 0.440140932112704 0.513374775385438 FN1/SERP1/CXCR4 3 GO:0001895 retina homeostasis 1/138 79/18722 0.443279384790443 0.515954214919198 ACTG1 1 GO:0006023 aminoglycan biosynthetic process 1/138 79/18722 0.443279384790443 0.515954214919198 IL1B 1 GO:0032272 negative regulation of protein polymerization 1/138 79/18722 0.443279384790443 0.515954214919198 SNCA 1 GO:0051279 regulation of release of sequestered calcium ion into cytosol 1/138 79/18722 0.443279384790443 0.515954214919198 SNCA 1 GO:1901184 regulation of ERBB signaling pathway 1/138 79/18722 0.443279384790443 0.515954214919198 PLAUR 1 GO:0016570 histone modification 4/138 463/18722 0.445875798232201 0.518759342174004 SNCA/IL1B/TAF10/JMJD6 4 GO:0001570 vasculogenesis 1/138 80/18722 0.447400365582103 0.519447316401749 JUNB 1 GO:0007422 peripheral nervous system development 1/138 80/18722 0.447400365582103 0.519447316401749 EGR3 1 GO:0021766 hippocampus development 1/138 80/18722 0.447400365582103 0.519447316401749 BTG2 1 GO:0051303 establishment of chromosome localization 1/138 80/18722 0.447400365582103 0.519447316401749 CHMP5 1 GO:0120193 tight junction organization 1/138 80/18722 0.447400365582103 0.519447316401749 ACTG1 1 GO:0001960 negative regulation of cytokine-mediated signaling pathway 1/138 81/18722 0.451491061298746 0.523323458390009 IL1R2 1 GO:0010833 telomere maintenance via telomere lengthening 1/138 81/18722 0.451491061298746 0.523323458390009 HNRNPA2B1 1 GO:0051817 modulation of process of other organism involved in symbiotic interaction 1/138 81/18722 0.451491061298746 0.523323458390009 JUN 1 GO:1903533 regulation of protein targeting 1/138 81/18722 0.451491061298746 0.523323458390009 BNIP3L 1 GO:0016064 immunoglobulin mediated immune response 2/138 207/18722 0.452376936717463 0.523952034649763 CD55/BCL3 2 GO:0033674 positive regulation of kinase activity 4/138 467/18722 0.452409895531218 0.523952034649763 EGR1/SNCA/HMGB1/IL1B 4 GO:0007265 Ras protein signal transduction 3/138 337/18722 0.453661387778425 0.525182879445655 JUN/GPR65/RHOB 3 GO:0002312 B cell activation involved in immune response 1/138 82/18722 0.455551692892587 0.526495166661158 BCL3 1 GO:0007032 endosome organization 1/138 82/18722 0.455551692892587 0.526495166661158 CHMP5 1 GO:0043242 negative regulation of protein-containing complex disassembly 1/138 82/18722 0.455551692892587 0.526495166661158 MID1IP1 1 GO:0050000 chromosome localization 1/138 82/18722 0.455551692892587 0.526495166661158 CHMP5 1 GO:0006790 sulfur compound metabolic process 3/138 339/18722 0.457500324528448 0.528527772172134 GPX1/SNCA/GLRX5 3 GO:0031397 negative regulation of protein ubiquitination 1/138 83/18722 0.459582479715592 0.529593911256765 IVNS1ABP 1 GO:0046785 microtubule polymerization 1/138 83/18722 0.459582479715592 0.529593911256765 SNCA 1 GO:0050672 negative regulation of lymphocyte proliferation 1/138 83/18722 0.459582479715592 0.529593911256765 CEBPB 1 GO:0050886 endocrine process 1/138 83/18722 0.459582479715592 0.529593911256765 IL1B 1 GO:0051899 membrane depolarization 1/138 83/18722 0.459582479715592 0.529593911256765 JUN 1 GO:1901292 nucleoside phosphate catabolic process 1/138 83/18722 0.459582479715592 0.529593911256765 PDE4B 1 GO:0019724 B cell mediated immunity 2/138 210/18722 0.459755260365197 0.529593911256765 CD55/BCL3 2 GO:0050807 regulation of synapse organization 2/138 211/18722 0.462202014396749 0.531364608243308 SNCA/SRGN 2 GO:0002088 lens development in camera-type eye 1/138 84/18722 0.463583639530993 0.531364608243308 SKIL 1 GO:0006405 RNA export from nucleus 1/138 84/18722 0.463583639530993 0.531364608243308 HNRNPA2B1 1 GO:0006835 dicarboxylic acid transport 1/138 84/18722 0.463583639530993 0.531364608243308 SNCA 1 GO:0010660 regulation of muscle cell apoptotic process 1/138 84/18722 0.463583639530993 0.531364608243308 PPP1R10 1 GO:0015844 monoamine transport 1/138 84/18722 0.463583639530993 0.531364608243308 SNCA 1 GO:0032508 DNA duplex unwinding 1/138 84/18722 0.463583639530993 0.531364608243308 ANXA1 1 GO:0032945 negative regulation of mononuclear cell proliferation 1/138 84/18722 0.463583639530993 0.531364608243308 CEBPB 1 GO:0042310 vasoconstriction 1/138 84/18722 0.463583639530993 0.531364608243308 PTGS2 1 GO:0042440 pigment metabolic process 1/138 84/18722 0.463583639530993 0.531364608243308 ALAS2 1 GO:0045445 myoblast differentiation 1/138 84/18722 0.463583639530993 0.531364608243308 DDX5 1 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 1/138 84/18722 0.463583639530993 0.531364608243308 PLK3 1 GO:0060021 roof of mouth development 1/138 85/18722 0.4675553885247 0.535696437325747 CSRNP1 1 GO:0044242 cellular lipid catabolic process 2/138 214/18722 0.469503658106063 0.537707275929701 PRDX6/IRS2 2 GO:0007059 chromosome segregation 3/138 346/18722 0.470847281344531 0.537778184706656 DUSP1/RIOK3/CHMP5 3 GO:0009798 axis specification 1/138 86/18722 0.471497941316651 0.537778184706656 ETS2 1 GO:0022406 membrane docking 1/138 86/18722 0.471497941316651 0.537778184706656 PLEK 1 GO:0032413 negative regulation of ion transmembrane transporter activity 1/138 86/18722 0.471497941316651 0.537778184706656 C4orf3 1 GO:0035023 regulation of Rho protein signal transduction 1/138 86/18722 0.471497941316651 0.537778184706656 GPR65 1 GO:0045921 positive regulation of exocytosis 1/138 86/18722 0.471497941316651 0.537778184706656 SNCA 1 GO:0046928 regulation of neurotransmitter secretion 1/138 86/18722 0.471497941316651 0.537778184706656 SNCA 1 GO:0060761 negative regulation of response to cytokine stimulus 1/138 86/18722 0.471497941316651 0.537778184706656 IL1R2 1 GO:1903510 mucopolysaccharide metabolic process 1/138 86/18722 0.471497941316651 0.537778184706656 IL1B 1 GO:2001251 negative regulation of chromosome organization 1/138 86/18722 0.471497941316651 0.537778184706656 DUSP1 1 GO:0043410 positive regulation of MAPK cascade 4/138 480/18722 0.473472391231496 0.539808957311451 OSM/HMGB1/IL1B/MIF 4 GO:0043087 regulation of GTPase activity 3/138 348/18722 0.474634217080737 0.54091178864892 GPR65/FGD3/ZC3H15 3 GO:0048041 focal adhesion assembly 1/138 87/18722 0.475411510972066 0.54091178864892 ACTG1 1 GO:0051262 protein tetramerization 1/138 87/18722 0.475411510972066 0.54091178864892 SNCA 1 GO:0150104 transport across blood-brain barrier 1/138 87/18722 0.475411510972066 0.54091178864892 SLC2A3 1 GO:1900182 positive regulation of protein localization to nucleus 1/138 87/18722 0.475411510972066 0.54091178864892 PTGS2 1 GO:0070374 positive regulation of ERK1 and ERK2 cascade 2/138 217/18722 0.476746586897997 0.542209134179455 HMGB1/MIF 2 GO:0007163 establishment or maintenance of cell polarity 2/138 218/18722 0.479147682060992 0.543997401297773 MYH9/RHOB 2 GO:0042445 hormone metabolic process 2/138 218/18722 0.479147682060992 0.543997401297773 EGR1/HIF1A 2 GO:0050803 regulation of synapse structure or activity 2/138 218/18722 0.479147682060992 0.543997401297773 SNCA/SRGN 2 GO:0010232 vascular transport 1/138 88/18722 0.479296309012627 0.543997401297773 SLC2A3 1 GO:0030101 natural killer cell activation 1/138 88/18722 0.479296309012627 0.543997401297773 NFIL3 1 GO:0034660 ncRNA metabolic process 4/138 485/18722 0.481495913570191 0.546100937866198 RIOK3/DDX21/HNRNPA2B1/RPL7 4 GO:0034764 positive regulation of transmembrane transport 2/138 219/18722 0.481542113375368 0.546100937866198 SNCA/IRS2 2 GO:0010657 muscle cell apoptotic process 1/138 89/18722 0.483152545427581 0.547481080588338 PPP1R10 1 GO:0014910 regulation of smooth muscle cell migration 1/138 89/18722 0.483152545427581 0.547481080588338 TRIB1 1 GO:0006066 alcohol metabolic process 3/138 353/18722 0.484047799869388 0.548272294276152 PLEK/SNCA/IDI1 3 GO:0010810 regulation of cell-substrate adhesion 2/138 221/18722 0.486310854473539 0.550027002041268 FN1/ACTG1 2 GO:0034644 cellular response to UV 1/138 90/18722 0.486980428684759 0.550027002041268 PTGS2 1 GO:0035278 miRNA mediated inhibition of translation 1/138 90/18722 0.486980428684759 0.550027002041268 ZFP36 1 GO:0040033 negative regulation of translation, ncRNA-mediated 1/138 90/18722 0.486980428684759 0.550027002041268 ZFP36 1 GO:0070664 negative regulation of leukocyte proliferation 1/138 90/18722 0.486980428684759 0.550027002041268 CEBPB 1 GO:0099175 regulation of postsynapse organization 1/138 90/18722 0.486980428684759 0.550027002041268 SRGN 1 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 1/138 90/18722 0.486980428684759 0.550027002041268 JUN 1 GO:0002275 myeloid cell activation involved in immune response 1/138 91/18722 0.490780165741516 0.552972146258559 HMGB1 1 GO:0006354 DNA-templated transcription, elongation 1/138 91/18722 0.490780165741516 0.552972146258559 HMGN1 1 GO:0045974 regulation of translation, ncRNA-mediated 1/138 91/18722 0.490780165741516 0.552972146258559 ZFP36 1 GO:0051952 regulation of amine transport 1/138 91/18722 0.490780165741516 0.552972146258559 SNCA 1 GO:0051983 regulation of chromosome segregation 1/138 91/18722 0.490780165741516 0.552972146258559 DUSP1 1 GO:1990874 vascular associated smooth muscle cell proliferation 1/138 91/18722 0.490780165741516 0.552972146258559 JUN 1 GO:1904062 regulation of cation transmembrane transport 3/138 357/18722 0.491521639037622 0.553583456674101 SNCA/C4orf3/PDE4B 3 GO:0031058 positive regulation of histone modification 1/138 92/18722 0.494551962055599 0.556096206222517 IL1B 1 GO:0032465 regulation of cytokinesis 1/138 92/18722 0.494551962055599 0.556096206222517 PLK3 1 GO:0035249 synaptic transmission, glutamatergic 1/138 92/18722 0.494551962055599 0.556096206222517 PTGS2 1 GO:0048525 negative regulation of viral process 1/138 92/18722 0.494551962055599 0.556096206222517 ZFP36 1 GO:0008037 cell recognition 2/138 225/18722 0.495766986817406 0.557237287686931 CXCR4/JMJD6 2 GO:0051495 positive regulation of cytoskeleton organization 2/138 226/18722 0.498113901476641 0.558725958139189 PLEK/GPR65 2 GO:0007589 body fluid secretion 1/138 93/18722 0.498296021595927 0.558725958139189 HIF1A 1 GO:0090398 cellular senescence 1/138 93/18722 0.498296021595927 0.558725958139189 YBX1 1 GO:0097306 cellular response to alcohol 1/138 93/18722 0.498296021595927 0.558725958139189 KLF2 1 GO:1901992 positive regulation of mitotic cell cycle phase transition 1/138 93/18722 0.498296021595927 0.558725958139189 ANXA1 1 GO:1902807 negative regulation of cell cycle G1/S phase transition 1/138 93/18722 0.498296021595927 0.558725958139189 PLK3 1 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 1/138 94/18722 0.502012546853309 0.561761527098013 CCNL1 1 GO:0001738 morphogenesis of a polarized epithelium 1/138 94/18722 0.502012546853309 0.561761527098013 ACTG1 1 GO:0014020 primary neural tube formation 1/138 94/18722 0.502012546853309 0.561761527098013 HIF1A 1 GO:1902414 protein localization to cell junction 1/138 94/18722 0.502012546853309 0.561761527098013 ACTG1 1 GO:1990830 cellular response to leukemia inhibitory factor 1/138 94/18722 0.502012546853309 0.561761527098013 SOCS3 1 GO:0006942 regulation of striated muscle contraction 1/138 95/18722 0.505701738851068 0.564527853679311 PDE4B 1 GO:0008593 regulation of Notch signaling pathway 1/138 95/18722 0.505701738851068 0.564527853679311 NFKBIA 1 GO:0030516 regulation of axon extension 1/138 95/18722 0.505701738851068 0.564527853679311 FN1 1 GO:0048709 oligodendrocyte differentiation 1/138 95/18722 0.505701738851068 0.564527853679311 CXCR4 1 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 1/138 95/18722 0.505701738851068 0.564527853679311 IVNS1ABP 1 GO:1990823 response to leukemia inhibitory factor 1/138 95/18722 0.505701738851068 0.564527853679311 SOCS3 1 GO:0006637 acyl-CoA metabolic process 1/138 96/18722 0.509363797155601 0.567705025023644 SNCA 1 GO:0035383 thioester metabolic process 1/138 96/18722 0.509363797155601 0.567705025023644 SNCA 1 GO:0051304 chromosome separation 1/138 96/18722 0.509363797155601 0.567705025023644 DUSP1 1 GO:1904035 regulation of epithelial cell apoptotic process 1/138 96/18722 0.509363797155601 0.567705025023644 ZFP36 1 GO:0140694 non-membrane-bounded organelle assembly 3/138 367/18722 0.509973554652494 0.568157086708524 ACTG1/CHMP5/KRT19 3 GO:0010596 negative regulation of endothelial cell migration 1/138 97/18722 0.512998919886865 0.570842060793741 HMGB1 1 GO:0014909 smooth muscle cell migration 1/138 97/18722 0.512998919886865 0.570842060793741 TRIB1 1 GO:0070252 actin-mediated cell contraction 1/138 97/18722 0.512998919886865 0.570842060793741 PDE4B 1 GO:0007160 cell-matrix adhesion 2/138 233/18722 0.514347607590652 0.571885494176901 FN1/ACTG1 2 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 2/138 233/18722 0.514347607590652 0.571885494176901 GPR65/PDE4B 2 GO:1904029 regulation of cyclin-dependent protein kinase activity 1/138 98/18722 0.516607303728778 0.573745107486517 CCNL1 1 GO:0048588 developmental cell growth 2/138 234/18722 0.516638605591524 0.573745107486517 FN1/CXCR4 2 GO:0060560 developmental growth involved in morphogenesis 2/138 234/18722 0.516638605591524 0.573745107486517 FN1/CXCR4 2 GO:0000045 autophagosome assembly 1/138 99/18722 0.52018914393955 0.576078944521993 GABARAPL2 1 GO:0007631 feeding behavior 1/138 99/18722 0.52018914393955 0.576078944521993 FOS 1 GO:0010717 regulation of epithelial to mesenchymal transition 1/138 99/18722 0.52018914393955 0.576078944521993 IL1B 1 GO:0015837 amine transport 1/138 99/18722 0.52018914393955 0.576078944521993 SNCA 1 GO:0031341 regulation of cell killing 1/138 99/18722 0.52018914393955 0.576078944521993 CD55 1 GO:0051153 regulation of striated muscle cell differentiation 1/138 99/18722 0.52018914393955 0.576078944521993 YBX1 1 GO:0060291 long-term synaptic potentiation 1/138 99/18722 0.52018914393955 0.576078944521993 SNCA 1 GO:0031334 positive regulation of protein-containing complex assembly 2/138 237/18722 0.523468962629206 0.57771752573496 PLEK/SNCA 2 GO:0006626 protein targeting to mitochondrion 1/138 100/18722 0.523744634361949 0.57771752573496 BNIP3L 1 GO:0006641 triglyceride metabolic process 1/138 100/18722 0.523744634361949 0.57771752573496 GPX1 1 GO:0006910 phagocytosis, recognition 1/138 100/18722 0.523744634361949 0.57771752573496 JMJD6 1 GO:0009062 fatty acid catabolic process 1/138 100/18722 0.523744634361949 0.57771752573496 IRS2 1 GO:0019218 regulation of steroid metabolic process 1/138 100/18722 0.523744634361949 0.57771752573496 EGR1 1 GO:0044728 DNA methylation or demethylation 1/138 100/18722 0.523744634361949 0.57771752573496 FOS 1 GO:0045807 positive regulation of endocytosis 1/138 100/18722 0.523744634361949 0.57771752573496 SNCA 1 GO:0051588 regulation of neurotransmitter transport 1/138 100/18722 0.523744634361949 0.57771752573496 SNCA 1 GO:0060079 excitatory postsynaptic potential 1/138 100/18722 0.523744634361949 0.57771752573496 SNCA 1 GO:0050830 defense response to Gram-positive bacterium 1/138 101/18722 0.527273967433481 0.581149881729654 HMGB2 1 GO:0051963 regulation of synapse assembly 1/138 101/18722 0.527273967433481 0.581149881729654 SNCA 1 GO:0050851 antigen receptor-mediated signaling pathway 2/138 240/18722 0.530234954218766 0.58385506761615 NFKBIZ/PDE4B 2 GO:0001841 neural tube formation 1/138 102/18722 0.5307773341965 0.58385506761615 HIF1A 1 GO:0010522 regulation of calcium ion transport into cytosol 1/138 102/18722 0.5307773341965 0.58385506761615 SNCA 1 GO:0045833 negative regulation of lipid metabolic process 1/138 102/18722 0.5307773341965 0.58385506761615 IL1B 1 GO:1904063 negative regulation of cation transmembrane transport 1/138 102/18722 0.5307773341965 0.58385506761615 C4orf3 1 GO:0071824 protein-DNA complex subunit organization 2/138 241/18722 0.532475896397718 0.585492066248459 HMGB1/HMGB2 2 GO:0019395 fatty acid oxidation 1/138 103/18722 0.534254924308255 0.586984387820716 IRS2 1 GO:1905037 autophagosome organization 1/138 103/18722 0.534254924308255 0.586984387820716 GABARAPL2 1 GO:0032535 regulation of cellular component size 3/138 382/18722 0.53698829138187 0.589754702018842 FN1/PPP1R15A/PLEK 3 GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 1/138 104/18722 0.537706926050854 0.589845634686452 GPR65 1 GO:0022600 digestive system process 1/138 104/18722 0.537706926050854 0.589845634686452 SGK1 1 GO:0032963 collagen metabolic process 1/138 104/18722 0.537706926050854 0.589845634686452 HIF1A 1 GO:0006898 receptor-mediated endocytosis 2/138 244/18722 0.539155325694697 0.591201446575391 CXCL8/SNCA 2 GO:0000041 transition metal ion transport 1/138 105/18722 0.541133526341164 0.592903387325771 FTH1 1 GO:0016079 synaptic vesicle exocytosis 1/138 105/18722 0.541133526341164 0.592903387325771 SNCA 1 GO:0006766 vitamin metabolic process 1/138 106/18722 0.544534910740633 0.595692081993389 SLC2A3 1 GO:0035821 modulation of process of other organism 1/138 106/18722 0.544534910740633 0.595692081993389 JUN 1 GO:0046620 regulation of organ growth 1/138 106/18722 0.544534910740633 0.595692081993389 SERP1 1 GO:0099565 chemical synaptic transmission, postsynaptic 1/138 106/18722 0.544534910740633 0.595692081993389 SNCA 1 GO:0006275 regulation of DNA replication 1/138 107/18722 0.547911263465053 0.598444680621366 JUN 1 GO:0032526 response to retinoic acid 1/138 107/18722 0.547911263465053 0.598444680621366 DUSP1 1 GO:0042303 molting cycle 1/138 107/18722 0.547911263465053 0.598444680621366 PTGS2 1 GO:0042633 hair cycle 1/138 107/18722 0.547911263465053 0.598444680621366 PTGS2 1 GO:0006958 complement activation, classical pathway 1/138 108/18722 0.55126276739424 0.601161552373891 CD55 1 GO:0007173 epidermal growth factor receptor signaling pathway 1/138 108/18722 0.55126276739424 0.601161552373891 PLAUR 1 GO:0034440 lipid oxidation 1/138 108/18722 0.55126276739424 0.601161552373891 IRS2 1 GO:0034446 substrate adhesion-dependent cell spreading 1/138 108/18722 0.55126276739424 0.601161552373891 FN1 1 GO:0006302 double-strand break repair 2/138 251/18722 0.554485658729531 0.60431592331999 HMGB1/HMGB2 2 GO:0034766 negative regulation of ion transmembrane transport 1/138 109/18722 0.554589604081658 0.60431592331999 C4orf3 1 GO:0090257 regulation of muscle system process 2/138 252/18722 0.556646377700599 0.60631971394942 PTGS2/PDE4B 2 GO:0006939 smooth muscle contraction 1/138 110/18722 0.557891953763962 0.606726575742519 PTGS2 1 GO:0009408 response to heat 1/138 110/18722 0.557891953763962 0.606726575742519 PTGS2 1 GO:0018958 phenol-containing compound metabolic process 1/138 110/18722 0.557891953763962 0.606726575742519 SNCA 1 GO:0061387 regulation of extent of cell growth 1/138 110/18722 0.557891953763962 0.606726575742519 FN1 1 GO:0008654 phospholipid biosynthetic process 2/138 253/18722 0.558799731722977 0.607476427103534 SOCS3/IDI1 2 GO:0043547 positive regulation of GTPase activity 2/138 255/18722 0.563084307252199 0.611895207763713 GPR65/ZC3H15 2 GO:0010633 negative regulation of epithelial cell migration 1/138 112/18722 0.564423906532639 0.612872310526857 HMGB1 1 GO:0043406 positive regulation of MAP kinase activity 1/138 112/18722 0.564423906532639 0.612872310526857 IL1B 1 GO:1903522 regulation of blood circulation 2/138 256/18722 0.565215511257242 0.613492499153239 PTGS2/PDE4B 2 GO:0042593 glucose homeostasis 2/138 258/18722 0.569455711916654 0.617613112339847 HIF1A/IRS2 2 GO:0045165 cell fate commitment 2/138 258/18722 0.569455711916654 0.617613112339847 MCL1/ETS2 2 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 1/138 114/18722 0.570860041615962 0.618895012005151 LRG1 1 GO:0033500 carbohydrate homeostasis 2/138 259/18722 0.571564694177685 0.619417657280567 HIF1A/IRS2 2 GO:0006260 DNA replication 2/138 260/18722 0.573666255636147 0.621377127910926 JUN/DDX21 2 GO:0051209 release of sequestered calcium ion into cytosol 1/138 115/18722 0.574042614394176 0.621377127910926 SNCA 1 GO:0090630 activation of GTPase activity 1/138 115/18722 0.574042614394176 0.621377127910926 GPR65 1 GO:0006720 isoprenoid metabolic process 1/138 116/18722 0.577201754460474 0.623584038301047 IDI1 1 GO:0018107 peptidyl-threonine phosphorylation 1/138 116/18722 0.577201754460474 0.623584038301047 DDIT4 1 GO:0030518 intracellular steroid hormone receptor signaling pathway 1/138 116/18722 0.577201754460474 0.623584038301047 DDX5 1 GO:0043200 response to amino acid 1/138 116/18722 0.577201754460474 0.623584038301047 CEBPB 1 GO:0051283 negative regulation of sequestering of calcium ion 1/138 116/18722 0.577201754460474 0.623584038301047 SNCA 1 GO:0043588 skin development 2/138 263/18722 0.579926358134253 0.626242587400135 ZFP36/ANXA1 2 GO:0030301 cholesterol transport 1/138 117/18722 0.580337633095562 0.626242587400135 NFKBIA 1 GO:0051225 spindle assembly 1/138 117/18722 0.580337633095562 0.626242587400135 CHMP5 1 GO:0006325 chromatin organization 3/138 409/18722 0.583432641249173 0.62838332809549 HMGB1/HMGN1/HMGB2 3 GO:0022612 gland morphogenesis 1/138 118/18722 0.583450420337315 0.62838332809549 CEBPB 1 GO:0030203 glycosaminoglycan metabolic process 1/138 118/18722 0.583450420337315 0.62838332809549 IL1B 1 GO:0051282 regulation of sequestering of calcium ion 1/138 118/18722 0.583450420337315 0.62838332809549 SNCA 1 GO:0071346 cellular response to interferon-gamma 1/138 118/18722 0.583450420337315 0.62838332809549 ACTG1 1 GO:0032412 regulation of ion transmembrane transporter activity 2/138 267/18722 0.588168964153366 0.633220203960858 C4orf3/PDE4B 2 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 3/138 412/18722 0.588410262713557 0.633235019772556 TRIB1/PLK3/UBE2S 3 GO:0006304 DNA modification 1/138 120/18722 0.589607394631795 0.633298872736505 FOS 1 GO:0007052 mitotic spindle organization 1/138 120/18722 0.589607394631795 0.633298872736505 CHMP5 1 GO:0032411 positive regulation of transporter activity 1/138 120/18722 0.589607394631795 0.633298872736505 SGK1 1 GO:0048675 axon extension 1/138 120/18722 0.589607394631795 0.633298872736505 FN1 1 GO:0072655 establishment of protein localization to mitochondrion 1/138 120/18722 0.589607394631795 0.633298872736505 BNIP3L 1 GO:0001894 tissue homeostasis 2/138 268/18722 0.590210985077131 0.633702612449712 PTGS2/ACTG1 2 GO:0001558 regulation of cell growth 3/138 414/18722 0.591707749719192 0.634853841873806 FN1/CXCR4/SGK1 3 GO:0001838 embryonic epithelial tube formation 1/138 121/18722 0.592651915626355 0.634853841873806 HIF1A 1 GO:0003206 cardiac chamber morphogenesis 1/138 121/18722 0.592651915626355 0.634853841873806 HIF1A 1 GO:0038127 ERBB signaling pathway 1/138 121/18722 0.592651915626355 0.634853841873806 PLAUR 1 GO:0043500 muscle adaptation 1/138 121/18722 0.592651915626355 0.634853841873806 IL1B 1 GO:1904019 epithelial cell apoptotic process 1/138 121/18722 0.592651915626355 0.634853841873806 ZFP36 1 GO:0051208 sequestering of calcium ion 1/138 122/18722 0.595674013128832 0.637355162836424 SNCA 1 GO:0051928 positive regulation of calcium ion transport 1/138 122/18722 0.595674013128832 0.637355162836424 SNCA 1 GO:0072329 monocarboxylic acid catabolic process 1/138 122/18722 0.595674013128832 0.637355162836424 IRS2 1 GO:0003231 cardiac ventricle development 1/138 123/18722 0.59867385109594 0.639826930721967 HIF1A 1 GO:0010811 positive regulation of cell-substrate adhesion 1/138 123/18722 0.59867385109594 0.639826930721967 FN1 1 GO:0071482 cellular response to light stimulus 1/138 123/18722 0.59867385109594 0.639826930721967 PTGS2 1 GO:0001909 leukocyte mediated cytotoxicity 1/138 124/18722 0.601651592294325 0.642515879261361 TREM1 1 GO:0007368 determination of left/right symmetry 1/138 124/18722 0.601651592294325 0.642515879261361 HIF1A 1 GO:0018210 peptidyl-threonine modification 1/138 125/18722 0.604607398309133 0.64493000747195 DDIT4 1 GO:0051053 negative regulation of DNA metabolic process 1/138 125/18722 0.604607398309133 0.64493000747195 DUSP1 1 GO:0070585 protein localization to mitochondrion 1/138 125/18722 0.604607398309133 0.64493000747195 BNIP3L 1 GO:0006911 phagocytosis, engulfment 1/138 127/18722 0.610453845272127 0.650667580004722 MYH9 1 GO:0035270 endocrine system development 1/138 127/18722 0.610453845272127 0.650667580004722 ANXA1 1 GO:0050808 synapse organization 3/138 426/18722 0.611136847398255 0.651146189245537 SNCA/ACTG1/SRGN 3 GO:0001952 regulation of cell-matrix adhesion 1/138 128/18722 0.613344803559433 0.652250129272412 ACTG1 1 GO:0006639 acylglycerol metabolic process 1/138 128/18722 0.613344803559433 0.652250129272412 GPX1 1 GO:0033865 nucleoside bisphosphate metabolic process 1/138 128/18722 0.613344803559433 0.652250129272412 SNCA 1 GO:0033875 ribonucleoside bisphosphate metabolic process 1/138 128/18722 0.613344803559433 0.652250129272412 SNCA 1 GO:0034032 purine nucleoside bisphosphate metabolic process 1/138 128/18722 0.613344803559433 0.652250129272412 SNCA 1 GO:0098813 nuclear chromosome segregation 2/138 281/18722 0.616078395537595 0.654052191441514 DUSP1/CHMP5 2 GO:0006022 aminoglycan metabolic process 1/138 129/18722 0.61621446135812 0.654052191441514 IL1B 1 GO:0006334 nucleosome assembly 1/138 129/18722 0.61621446135812 0.654052191441514 HMGB2 1 GO:0007127 meiosis I 1/138 129/18722 0.61621446135812 0.654052191441514 UBB 1 GO:0007498 mesoderm development 1/138 129/18722 0.61621446135812 0.654052191441514 ETS2 1 GO:0006282 regulation of DNA repair 1/138 130/18722 0.619062974472334 0.656074736464778 HMGB1 1 GO:0007098 centrosome cycle 1/138 130/18722 0.619062974472334 0.656074736464778 CHMP5 1 GO:0015918 sterol transport 1/138 130/18722 0.619062974472334 0.656074736464778 NFKBIA 1 GO:0030534 adult behavior 1/138 130/18722 0.619062974472334 0.656074736464778 SNCA 1 GO:0015850 organic hydroxy compound transport 2/138 284/18722 0.621868871783159 0.658569731640386 NFKBIA/SNCA 2 GO:0006661 phosphatidylinositol biosynthetic process 1/138 131/18722 0.621890497574896 0.658569731640386 SOCS3 1 GO:0048562 embryonic organ morphogenesis 2/138 285/18722 0.623784149000275 0.660323806263889 FBN1/HIF1A 2 GO:0072175 epithelial tube formation 1/138 132/18722 0.624697184215456 0.661038883525328 HIF1A 1 GO:0007389 pattern specification process 3/138 436/18722 0.6268552014069 0.663070325167389 BTG2/HIF1A/ETS2 3 GO:0009855 determination of bilateral symmetry 1/138 133/18722 0.627483186828596 0.663482412212759 HIF1A 1 GO:0009799 specification of symmetry 1/138 134/18722 0.630248656741859 0.66564782228182 HIF1A 1 GO:0032147 activation of protein kinase activity 1/138 134/18722 0.630248656741859 0.66564782228182 HMGB1 1 GO:0042552 myelination 1/138 134/18722 0.630248656741859 0.66564782228182 CXCR4 1 GO:0009581 detection of external stimulus 1/138 135/18722 0.632993744183737 0.668040041738089 CXCR4 1 GO:0061982 meiosis I cell cycle process 1/138 135/18722 0.632993744183737 0.668040041738089 UBB 1 GO:0002429 immune response-activating cell surface receptor signaling pathway 2/138 291/18722 0.635119878190407 0.669139507959717 NFKBIZ/PDE4B 2 GO:0002757 immune response-activating signal transduction 2/138 291/18722 0.635119878190407 0.669139507959717 NFKBIZ/PDE4B 2 GO:0007272 ensheathment of neurons 1/138 136/18722 0.635718598291589 0.669139507959717 CXCR4 1 GO:0008366 axon ensheathment 1/138 136/18722 0.635718598291589 0.669139507959717 CXCR4 1 GO:0043401 steroid hormone mediated signaling pathway 1/138 136/18722 0.635718598291589 0.669139507959717 DDX5 1 GO:0099024 plasma membrane invagination 1/138 136/18722 0.635718598291589 0.669139507959717 MYH9 1 GO:1900180 regulation of protein localization to nucleus 1/138 136/18722 0.635718598291589 0.669139507959717 PTGS2 1 GO:0000086 G2/M transition of mitotic cell cycle 1/138 137/18722 0.638423367119511 0.670464992714566 PLK3 1 GO:0007586 digestion 1/138 137/18722 0.638423367119511 0.670464992714566 SGK1 1 GO:0008203 cholesterol metabolic process 1/138 137/18722 0.638423367119511 0.670464992714566 IDI1 1 GO:0034754 cellular hormone metabolic process 1/138 137/18722 0.638423367119511 0.670464992714566 EGR1 1 GO:0060078 regulation of postsynaptic membrane potential 1/138 137/18722 0.638423367119511 0.670464992714566 SNCA 1 GO:0090090 negative regulation of canonical Wnt signaling pathway 1/138 137/18722 0.638423367119511 0.670464992714566 EGR1 1 GO:0009582 detection of abiotic stimulus 1/138 138/18722 0.641108197646146 0.673030597528941 CXCR4 1 GO:0016579 protein deubiquitination 1/138 139/18722 0.643773235782437 0.675573497429307 TAF10 1 GO:0050768 negative regulation of neurogenesis 1/138 140/18722 0.646418626379328 0.678093870039076 IL1B 1 GO:0030183 B cell differentiation 1/138 141/18722 0.649044513235406 0.680591891610451 BCL3 1 GO:0072006 nephron development 1/138 142/18722 0.651651039104494 0.682810557917096 EGR1 1 GO:0097553 calcium ion transmembrane import into cytosol 1/138 142/18722 0.651651039104494 0.682810557917096 SNCA 1 GO:0006865 amino acid transport 1/138 143/18722 0.65423834570318 0.684748144449774 SNCA 1 GO:0030010 establishment of cell polarity 1/138 143/18722 0.65423834570318 0.684748144449774 MYH9 1 GO:0031023 microtubule organizing center organization 1/138 143/18722 0.65423834570318 0.684748144449774 CHMP5 1 GO:0051056 regulation of small GTPase mediated signal transduction 2/138 302/18722 0.65521129318638 0.685508657495374 GPR65/FGD3 2 GO:0010324 membrane invagination 1/138 144/18722 0.656806573718302 0.686919464358525 MYH9 1 GO:0007269 neurotransmitter secretion 1/138 145/18722 0.659355862814377 0.688809071401055 SNCA 1 GO:0051961 negative regulation of nervous system development 1/138 145/18722 0.659355862814377 0.688809071401055 IL1B 1 GO:0099643 signal release from synapse 1/138 145/18722 0.659355862814377 0.688809071401055 SNCA 1 GO:0006310 DNA recombination 2/138 305/18722 0.660536724467824 0.689783753918932 HMGB1/HMGB2 2 GO:0048813 dendrite morphogenesis 1/138 146/18722 0.66188635164097 0.690933877200607 PHACTR1 1 GO:0016331 morphogenesis of embryonic epithelium 1/138 147/18722 0.664398177840019 0.692776369025393 HIF1A 1 GO:1902652 secondary alcohol metabolic process 1/138 147/18722 0.664398177840019 0.692776369025393 IDI1 1 GO:1902850 microtubule cytoskeleton organization involved in mitosis 1/138 147/18722 0.664398177840019 0.692776369025393 CHMP5 1 GO:0035148 tube formation 1/138 148/18722 0.666891478053105 0.694560821508645 HIF1A 1 GO:0044272 sulfur compound biosynthetic process 1/138 148/18722 0.666891478053105 0.694560821508645 SNCA 1 GO:0044839 cell cycle G2/M phase transition 1/138 148/18722 0.666891478053105 0.694560821508645 PLK3 1 GO:0022613 ribonucleoprotein complex biogenesis 3/138 463/18722 0.66710782461107 0.694560821508645 RIOK3/DDX21/RPL7 3 GO:0016525 negative regulation of angiogenesis 1/138 149/18722 0.669366387928666 0.696391273871207 KLF2 1 GO:1905039 carboxylic acid transmembrane transport 1/138 149/18722 0.669366387928666 0.696391273871207 IRS2 1 GO:1903825 organic acid transmembrane transport 1/138 150/18722 0.671823042129164 0.698685921616392 IRS2 1 GO:0006261 DNA-dependent DNA replication 1/138 151/18722 0.674261574338198 0.70043671570855 DDX21 1 GO:1904064 positive regulation of cation transmembrane transport 1/138 151/18722 0.674261574338198 0.70043671570855 SNCA 1 GO:2000181 negative regulation of blood vessel morphogenesis 1/138 151/18722 0.674261574338198 0.70043671570855 KLF2 1 GO:0016125 sterol metabolic process 1/138 152/18722 0.676682117267568 0.701903217426627 IDI1 1 GO:0021915 neural tube development 1/138 152/18722 0.676682117267568 0.701903217426627 HIF1A 1 GO:0051092 positive regulation of NF-kappaB transcription factor activity 1/138 152/18722 0.676682117267568 0.701903217426627 IL1B 1 GO:1901343 negative regulation of vasculature development 1/138 152/18722 0.676682117267568 0.701903217426627 KLF2 1 GO:0002768 immune response-regulating cell surface receptor signaling pathway 2/138 315/18722 0.677816478445588 0.702817905929237 NFKBIZ/PDE4B 2 GO:0007338 single fertilization 1/138 153/18722 0.679084802664287 0.703870765666559 MYH9 1 GO:0007605 sensory perception of sound 1/138 154/18722 0.681469761317544 0.706079801097068 GPX1 1 GO:0051147 regulation of muscle cell differentiation 1/138 155/18722 0.683837123065615 0.708268966688354 YBX1 1 GO:0008202 steroid metabolic process 2/138 319/18722 0.684527023156893 0.708719756490191 EGR1/IDI1 2 GO:0007030 Golgi organization 1/138 157/18722 0.688519570485869 0.71205870110077 PLK3 1 GO:0070646 protein modification by small protein removal 1/138 157/18722 0.688519570485869 0.71205870110077 TAF10 1 GO:1902600 proton transmembrane transport 1/138 157/18722 0.688519570485869 0.71205870110077 UQCRH 1 GO:0016049 cell growth 3/138 482/18722 0.693503285794449 0.716946376064618 FN1/CXCR4/SGK1 3 GO:0060402 calcium ion transport into cytosol 1/138 160/18722 0.695414456864577 0.718655192519167 SNCA 1 GO:0003205 cardiac chamber development 1/138 161/18722 0.69767891139279 0.720460263601534 HIF1A 1 GO:0051650 establishment of vesicle localization 1/138 161/18722 0.69767891139279 0.720460263601534 SNCA 1 GO:0003002 regionalization 2/138 331/18722 0.703979145663854 0.726696573584015 BTG2/ETS2 2 GO:0034765 regulation of ion transmembrane transport 3/138 491/18722 0.705450578099584 0.727945479737168 SNCA/C4orf3/PDE4B 3 GO:0007286 spermatid development 1/138 165/18722 0.706570808872455 0.728831193881409 HMGB2 1 GO:0009451 RNA modification 1/138 167/18722 0.710918898162233 0.732230678603069 JMJD6 1 GO:0034728 nucleosome organization 1/138 167/18722 0.710918898162233 0.732230678603069 HMGB2 1 GO:0034767 positive regulation of ion transmembrane transport 1/138 167/18722 0.710918898162233 0.732230678603069 SNCA 1 GO:0055088 lipid homeostasis 1/138 167/18722 0.710918898162233 0.732230678603069 IRS2 1 GO:0009152 purine ribonucleotide biosynthetic process 1/138 169/18722 0.715203016656429 0.736370697504566 SNCA 1 GO:0030178 negative regulation of Wnt signaling pathway 1/138 170/18722 0.717321379384905 0.738278623826993 EGR1 1 GO:0048515 spermatid differentiation 1/138 172/18722 0.72151128943278 0.742042098481681 HMGB2 1 GO:1901136 carbohydrate derivative catabolic process 1/138 172/18722 0.72151128943278 0.742042098481681 PDE4B 1 GO:0010469 regulation of signaling receptor activity 1/138 173/18722 0.723583065284978 0.743897920461062 HIF1A 1 GO:0048771 tissue remodeling 1/138 175/18722 0.727680823754334 0.747834465475743 HIF1A 1 GO:0051648 vesicle localization 1/138 177/18722 0.73171826848541 0.751706142929087 SNCA 1 GO:0035265 organ growth 1/138 178/18722 0.733714649124343 0.753478918270497 SERP1 1 GO:0007416 synapse assembly 1/138 179/18722 0.735696280833836 0.755235245134845 SNCA 1 GO:0031346 positive regulation of cell projection organization 2/138 353/18722 0.737065776721769 0.756362115271638 FN1/SKIL 2 GO:0015698 inorganic anion transport 1/138 180/18722 0.737663271787022 0.756696234936706 CEBPB 1 GO:0009260 ribonucleotide biosynthetic process 1/138 182/18722 0.74155376018478 0.759846875771076 SNCA 1 GO:0060401 cytosolic calcium ion transport 1/138 182/18722 0.74155376018478 0.759846875771076 SNCA 1 GO:0061138 morphogenesis of a branching epithelium 1/138 182/18722 0.74155376018478 0.759846875771076 SOCS3 1 GO:2001257 regulation of cation channel activity 1/138 184/18722 0.745386964053181 0.763493529981598 PDE4B 1 GO:0140013 meiotic nuclear division 1/138 185/18722 0.74728234645477 0.765153337080068 UBB 1 GO:1902115 regulation of organelle assembly 1/138 186/18722 0.749163720797395 0.76679758550171 CHMP5 1 GO:0008064 regulation of actin polymerization or depolymerization 1/138 187/18722 0.751031189859219 0.768155745734941 PLEK 1 GO:0031589 cell-substrate adhesion 2/138 363/18722 0.751042682049865 0.768155745734941 FN1/ACTG1 2 GO:0006575 cellular modified amino acid metabolic process 1/138 188/18722 0.752884855669816 0.769474312643812 GPX1 1 GO:0030832 regulation of actin filament length 1/138 188/18722 0.752884855669816 0.769474312643812 PLEK 1 GO:0046578 regulation of Ras protein signal transduction 1/138 189/18722 0.75472481951559 0.77107164930686 GPR65 1 GO:0009566 fertilization 1/138 190/18722 0.75655118194514 0.771804229968227 MYH9 1 GO:0009755 hormone-mediated signaling pathway 1/138 190/18722 0.75655118194514 0.771804229968227 DDX5 1 GO:0046390 ribose phosphate biosynthetic process 1/138 190/18722 0.75655118194514 0.771804229968227 SNCA 1 GO:0051216 cartilage development 1/138 190/18722 0.75655118194514 0.771804229968227 HIF1A 1 GO:0006164 purine nucleotide biosynthetic process 1/138 191/18722 0.758364042774601 0.773370146955556 SNCA 1 GO:0001763 morphogenesis of a branching structure 1/138 196/18722 0.76722926587684 0.782124193016574 SOCS3 1 GO:0072522 purine-containing compound biosynthetic process 1/138 200/18722 0.774088332079146 0.788827472785157 SNCA 1 GO:0007018 microtubule-based movement 2/138 382/18722 0.77585553161983 0.790338925511709 HIF1A/UBB 2 GO:0022412 cellular process involved in reproduction in multicellular organism 2/138 384/18722 0.778338731816174 0.792578371988442 UBB/HMGB2 2 GO:0009100 glycoprotein metabolic process 2/138 387/18722 0.782018763172682 0.796034461561658 SERP1/HIF1A 2 GO:0060348 bone development 1/138 205/18722 0.78238062482754 0.796111619340053 FBN1 1 GO:0008016 regulation of heart contraction 1/138 206/18722 0.784002457401597 0.797470335873042 PDE4B 1 GO:0006836 neurotransmitter transport 1/138 208/18722 0.787210210845957 0.800440634557653 SNCA 1 GO:0030100 regulation of endocytosis 1/138 211/18722 0.791933374305691 0.804655195579678 SNCA 1 GO:0046474 glycerophospholipid biosynthetic process 1/138 211/18722 0.791933374305691 0.804655195579678 SOCS3 1 GO:0006457 protein folding 1/138 212/18722 0.793484516564122 0.805642980517312 AHSP 1 GO:0030258 lipid modification 1/138 212/18722 0.793484516564122 0.805642980517312 IRS2 1 GO:0001505 regulation of neurotransmitter levels 1/138 213/18722 0.795024178191034 0.806911848251513 SNCA 1 GO:0008154 actin polymerization or depolymerization 1/138 217/18722 0.801069696322855 0.812751354307877 PLEK 1 GO:0031503 protein-containing complex localization 1/138 220/18722 0.805487360924019 0.816638005628978 HNRNPA2B1 1 GO:0048705 skeletal system morphogenesis 1/138 220/18722 0.805487360924019 0.816638005628978 CSRNP1 1 GO:0010001 glial cell differentiation 1/138 225/18722 0.812634727341987 0.823584284848052 CXCR4 1 GO:0006486 protein glycosylation 1/138 226/18722 0.814032597679166 0.824400552889782 SERP1 1 GO:0043413 macromolecule glycosylation 1/138 226/18722 0.814032597679166 0.824400552889782 SERP1 1 GO:0046777 protein autophosphorylation 1/138 227/18722 0.815420113981084 0.825505339108533 STK17B 1 GO:0007409 axonogenesis 2/138 418/18722 0.817027734076423 0.82683206688534 FN1/SKIL 2 GO:0016197 endosomal transport 1/138 230/18722 0.819521297267721 0.829054078624524 CHMP5 1 GO:0032271 regulation of protein polymerization 1/138 232/18722 0.822205030379582 0.831466787625863 SNCA 1 GO:0000209 protein polyubiquitination 1/138 236/18722 0.827454210114066 0.836167417119624 UBE2S 1 GO:0046395 carboxylic acid catabolic process 1/138 236/18722 0.827454210114066 0.836167417119624 IRS2 1 GO:0016054 organic acid catabolic process 1/138 240/18722 0.832549504228957 0.840705831012042 IRS2 1 GO:0070085 glycosylation 1/138 240/18722 0.832549504228957 0.840705831012042 SERP1 1 GO:0016358 dendrite development 1/138 243/18722 0.83627268689582 0.844159190290558 PHACTR1 1 GO:0006814 sodium ion transport 1/138 245/18722 0.838709031867967 0.846311543034283 SGK1 1 GO:0003007 heart morphogenesis 1/138 246/18722 0.839913672967833 0.847219917314056 HIF1A 1 GO:0016055 Wnt signaling pathway 2/138 444/18722 0.842447685006078 0.849468082381128 EGR1/HBP1 2 GO:0010975 regulation of neuron projection development 2/138 445/18722 0.843358829251862 0.849887355940327 FN1/SKIL 2 GO:0045926 negative regulation of growth 1/138 249/18722 0.843474264141999 0.849887355940327 HIF1A 1 GO:0198738 cell-cell signaling by wnt 2/138 446/18722 0.844265230487999 0.850376451845133 EGR1/HBP1 2 GO:0045017 glycerolipid biosynthetic process 1/138 252/18722 0.846956222907324 0.852778280879553 SOCS3 1 GO:0060828 regulation of canonical Wnt signaling pathway 1/138 253/18722 0.848099701046945 0.853620784091735 EGR1 1 GO:0006839 mitochondrial transport 1/138 254/18722 0.849234697054066 0.854145342212312 BNIP3L 1 GO:0009165 nucleotide biosynthetic process 1/138 254/18722 0.849234697054066 0.854145342212312 SNCA 1 GO:0006338 chromatin remodeling 1/138 255/18722 0.850361273391869 0.854969445032359 HMGB2 1 GO:1901293 nucleoside phosphate biosynthetic process 1/138 256/18722 0.851479492066906 0.85578455269852 SNCA 1 GO:0051091 positive regulation of DNA-binding transcription factor activity 1/138 260/18722 0.855870014473432 0.859886732952911 IL1B 1 GO:0090305 nucleic acid phosphodiester bond hydrolysis 1/138 261/18722 0.856947359181626 0.860658426778226 ZFP36 1 GO:0061564 axon development 2/138 467/18722 0.862238731315031 0.865660313582154 FN1/SKIL 2 GO:1903829 positive regulation of cellular protein localization 1/138 276/18722 0.872180340733247 0.875325599805491 PTGS2 1 GO:0007281 germ cell development 1/138 278/18722 0.874085751753148 0.876921646405555 HMGB2 1 GO:0048193 Golgi vesicle transport 1/138 296/18722 0.890013874902842 0.892579680668328 GABARAPL2 1 GO:0030198 extracellular matrix organization 1/138 301/18722 0.894071736216186 0.896326239873792 BCL3 1 GO:0043062 extracellular structure organization 1/138 302/18722 0.894865292505322 0.896798742903245 BCL3 1 GO:0060070 canonical Wnt signaling pathway 1/138 303/18722 0.895652946665705 0.897264993005996 EGR1 1 GO:0045229 external encapsulating structure organization 1/138 304/18722 0.896434742276766 0.897725040574394 BCL3 1 GO:0006605 protein targeting 1/138 314/18722 0.903939840220706 0.904915314868426 BNIP3L 1 GO:0009101 glycoprotein biosynthetic process 1/138 317/18722 0.906084214532531 0.906735839282284 SERP1 1 GO:0030111 regulation of Wnt signaling pathway 1/138 328/18722 0.91354815546517 0.913876533666272 EGR1 1 GO:0044282 small molecule catabolic process 1/138 376/18722 0.939801461179416 0.939801461179416 IRS2 1