ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	geneName	Count
hsa05150	Staphylococcus aureus infection	20/308	55/5868	1.30046236448978e-12	2.43186462159588e-10	2213/3117/3123/3119/2359/3122/3115/3113/3111/728/3108/1675/713/714/3684/2214/5724/6404/3109/712	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/FPR3/HLA-DRA/HLA-DPB1/HLA-DPA1/HLA-DOA/C5AR1/HLA-DMA/CFD/C1QB/C1QC/ITGAM/FCGR3A/PTAFR/SELPLG/HLA-DMB/C1QA	20
hsa05330	Allograft rejection	15/308	37/5868	1.48135051880435e-10	1.38506273508206e-08	3117/3123/3119/3105/3122/3115/3113/3106/3107/3111/3134/3108/942/3133/3109	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-A/HLA-DRA/HLA-DPB1/HLA-DPA1/HLA-B/HLA-C/HLA-DOA/HLA-F/HLA-DMA/CD86/HLA-E/HLA-DMB	15
hsa05140	Leishmaniasis	20/308	72/5868	3.54585707734693e-10	2.21025091154625e-08	3117/3123/3119/3122/3115/3113/3725/4792/6772/3111/653361/3108/4615/2353/3684/2214/3460/23118/7097/3109	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/HLA-DPB1/HLA-DPA1/JUN/NFKBIA/STAT1/HLA-DOA/NCF1/HLA-DMA/MYD88/FOS/ITGAM/FCGR3A/IFNGR2/TAB2/TLR2/HLA-DMB	20
hsa05332	Graft-versus-host disease	15/308	41/5868	8.28108619406298e-10	3.87140779572444e-08	3117/3123/3119/3105/3122/3115/3113/3106/3107/3111/3134/3108/942/3133/3109	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-A/HLA-DRA/HLA-DPB1/HLA-DPA1/HLA-B/HLA-C/HLA-DOA/HLA-F/HLA-DMA/CD86/HLA-E/HLA-DMB	15
hsa04940	Type I diabetes mellitus	15/308	43/5868	1.79715771035941e-09	6.7213698367442e-08	3117/3123/3119/3105/3122/3115/3113/3106/3107/3111/3134/3108/942/3133/3109	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-A/HLA-DRA/HLA-DPB1/HLA-DPA1/HLA-B/HLA-C/HLA-DOA/HLA-F/HLA-DMA/CD86/HLA-E/HLA-DMB	15
hsa04145	Phagosome	28/308	153/5868	3.93018552296917e-09	1.11745715295383e-07	2213/3117/3123/3119/3105/3122/3115/3113/3106/3107/64581/3111/653361/3134/948/9296/3108/4481/23480/5879/9550/3684/2214/526/3133/7037/7097/3109	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-A/HLA-DRA/HLA-DPB1/HLA-DPA1/HLA-B/HLA-C/CLEC7A/HLA-DOA/NCF1/HLA-F/CD36/ATP6V1F/HLA-DMA/MSR1/SEC61G/RAC1/ATP6V1G1/ITGAM/FCGR3A/ATP6V1B2/HLA-E/TFRC/TLR2/HLA-DMB	28
hsa05320	Autoimmune thyroid disease	16/308	52/5868	4.18299469020151e-09	1.11745715295383e-07	3117/3123/3119/3105/3122/3115/3113/3106/3107/3111/3134/3108/1081/942/3133/3109	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-A/HLA-DRA/HLA-DPB1/HLA-DPA1/HLA-B/HLA-C/HLA-DOA/HLA-F/HLA-DMA/CGA/CD86/HLA-E/HLA-DMB	16
hsa05323	Rheumatoid arthritis	21/308	91/5868	5.20868869848231e-09	1.21753098327024e-07	3117/3123/3119/3122/3115/7422/3113/3725/10673/3576/54/3111/9296/3108/9550/2353/942/526/7097/3109/6387	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/HLA-DPB1/VEGFA/HLA-DPA1/JUN/TNFSF13B/CXCL8/ACP5/HLA-DOA/ATP6V1F/HLA-DMA/ATP6V1G1/FOS/CD86/ATP6V1B2/TLR2/HLA-DMB/CXCL12	21
hsa04612	Antigen processing and presentation	18/308	76/5868	4.34867996655631e-08	9.03559059717811e-07	3117/3123/3119/3105/3122/3115/3113/567/972/3106/3107/3111/5721/3134/3108/3133/10437/3109	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-A/HLA-DRA/HLA-DPB1/HLA-DPA1/B2M/CD74/HLA-B/HLA-C/HLA-DOA/PSME2/HLA-F/HLA-DMA/HLA-E/IFI30/HLA-DMB	18
hsa05416	Viral myocarditis	17/308	70/5868	6.99855853011073e-08	1.30873044513071e-06	3117/3123/3119/3105/3122/3115/3113/3106/3107/3111/3134/3108/5879/54205/942/3133/3109	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-A/HLA-DRA/HLA-DPB1/HLA-DPA1/HLA-B/HLA-C/HLA-DOA/HLA-F/HLA-DMA/RAC1/CYCS/CD86/HLA-E/HLA-DMB	17
hsa04380	Osteoclast differentiation	22/308	128/5868	6.14076980624648e-07	1.01439873672818e-05	2213/54209/3727/3725/4792/6772/54/653361/2354/3726/2885/5879/9021/2353/2214/3460/23118/6688/8878/7305/5291/126014	FCGR2B/TREM2/JUND/JUN/NFKBIA/STAT1/ACP5/NCF1/FOSB/JUNB/GRB2/RAC1/SOCS3/FOS/FCGR3A/IFNGR2/TAB2/SPI1/SQSTM1/TYROBP/PIK3CB/OSCAR	22
hsa04672	Intestinal immune network for IgA production	13/308	48/5868	6.50951061002039e-07	1.01439873672818e-05	3117/7852/3123/3119/3122/3115/3113/10673/3111/3108/942/3109/6387	HLA-DQA1/CXCR4/HLA-DRB1/HLA-DQB1/HLA-DRA/HLA-DPB1/HLA-DPA1/TNFSF13B/HLA-DOA/HLA-DMA/CD86/HLA-DMB/CXCL12	13
hsa04514	Cell adhesion molecules (CAMs)	22/308	133/5868	1.21038561294871e-06	1.74109315093391e-05	3117/3123/3119/3105/3122/214/3115/3113/1462/3106/3107/3111/3134/3108/23705/3684/3384/965/942/6404/3133/3109	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-A/HLA-DRA/ALCAM/HLA-DPB1/HLA-DPA1/VCAN/HLA-B/HLA-C/HLA-DOA/HLA-F/HLA-DMA/CADM1/ITGAM/ICAM2/CD58/CD86/SELPLG/HLA-E/HLA-DMB	22
hsa00010	Glycolysis / Gluconeogenesis	14/308	65/5868	4.80379726831693e-06	6.41650063696619e-05	3939/3099/5230/2203/226/5315/7167/2597/2023/217/2821/2026/5223/224	LDHA/HK2/PGK1/FBP1/ALDOA/PKM/TPI1/GAPDH/ENO1/ALDH2/GPI/ENO2/PGAM1/ALDH3A2	14
hsa05310	Asthma	9/308	30/5868	1.4463995081704e-05	0.000180317805351909	3117/3123/3119/3122/3115/3113/3111/3108/3109	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/HLA-DPB1/HLA-DPA1/HLA-DOA/HLA-DMA/HLA-DMB	9
hsa05145	Toxoplasmosis	18/308	132/5868	0.00016165653224621	0.00188936072062758	3117/3123/3119/3122/3115/3113/4792/6772/240/3111/3108/4615/3460/54205/23118/5291/7097/3109	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/HLA-DPB1/HLA-DPA1/NFKBIA/STAT1/ALOX5/HLA-DOA/HLA-DMA/MYD88/IFNGR2/CYCS/TAB2/PIK3CB/TLR2/HLA-DMB	18
hsa05160	Hepatitis C	17/308	134/5868	0.000582199274447342	0.00640419201892076	3434/4939/4792/6772/5610/4938/4940/3576/3665/2885/9021/5516/1956/1026/6655/5291/975	IFIT1/OAS2/NFKBIA/STAT1/EIF2AK2/OAS1/OAS3/CXCL8/IRF7/GRB2/SOCS3/PPP2CB/EGFR/CDKN1A/SOS2/PIK3CB/CD81	17
hsa05322	Systemic lupus erythematosus	17/308	136/5868	0.000691827246173542	0.00718731639080291	2213/3117/3123/3119/3122/3115/3113/3111/6628/6741/3108/713/714/2214/942/3109/712	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/HLA-DPB1/HLA-DPA1/HLA-DOA/SNRPB/SSB/HLA-DMA/C1QB/C1QC/FCGR3A/CD86/HLA-DMB/C1QA	17
hsa05211	Renal cell carcinoma	11/308	70/5868	0.000934183947148531	0.00919433674298817	7422/3725/112399/5906/2885/5879/2889/54583/9978/6655/5291	VEGFA/JUN/EGLN3/RAP1A/GRB2/RAC1/RAPGEF1/EGLN1/RBX1/SOS2/PIK3CB	11
hsa04062	Chemokine signaling pathway	20/308	189/5868	0.00200742926951693	0.0187694636699833	7852/4792/6772/3576/653361/58191/2787/5906/2885/5613/5879/387/2920/6655/2921/2185/5473/6357/5291/6387	CXCR4/NFKBIA/STAT1/CXCL8/NCF1/CXCL16/GNG5/RAP1A/GRB2/PRKX/RAC1/RHOA/CXCL2/SOS2/CXCL3/PTK2B/PPBP/CCL13/PIK3CB/CXCL12	20
hsa04912	GnRH signaling pathway	13/308	101/5868	0.00222658710287842	0.019827228011346	3725/801/2776/1081/2885/5613/1956/10746/808/4323/4215/6655/2185	JUN/CALM1/GNAQ/CGA/GRB2/PRKX/EGFR/MAP3K2/CALM3/MMP14/MAP3K3/SOS2/PTK2B	13
hsa04722	Neurotrophin signaling pathway	15/308	127/5868	0.00250200231245827	0.0212670196558953	7533/3725/4792/801/8660/5906/2885/5879/2889/387/808/4215/6655/5291/8767	YWHAH/JUN/NFKBIA/CALM1/IRS2/RAP1A/GRB2/RAC1/RAPGEF1/RHOA/CALM3/MAP3K3/SOS2/PIK3CB/RIPK2	15
hsa05142	Chagas disease (American trypanosomiasis)	13/308	104/5868	0.00289767435262061	0.0235593523452197	3725/4792/3576/2776/713/4615/714/2353/5516/3460/5291/7097/712	JUN/NFKBIA/CXCL8/GNAQ/C1QB/MYD88/C1QC/FOS/PPP2CB/IFNGR2/PIK3CB/TLR2/C1QA	13
hsa05131	Shigellosis	9/308	61/5868	0.00417282295643135	0.0325132455355276	4792/3576/960/10093/5879/3059/7322/1729/8767	NFKBIA/CXCL8/CD44/ARPC4/RAC1/HCLS1/UBE2D2/DIAPH1/RIPK2	9
hsa04662	B cell receptor signaling pathway	10/308	75/5868	0.00544200233014252	0.0398924471890496	2213/8519/3725/4792/2885/5879/2353/6655/5291/975	FCGR2B/IFITM1/JUN/NFKBIA/GRB2/RAC1/FOS/SOS2/PIK3CB/CD81	10
hsa04910	Insulin signaling pathway	15/308	138/5868	0.00554654345944005	0.0398924471890496	3099/801/2203/8660/5500/79660/2885/5613/9021/2889/1978/808/6655/5291/1977	HK2/CALM1/FBP1/IRS2/PPP1CB/PPP1R3B/GRB2/PRKX/SOCS3/RAPGEF1/EIF4EBP1/CALM3/SOS2/PIK3CB/EIF4E	15
hsa05214	Glioma	9/308	65/5868	0.00640274688598183	0.0443449506547631	801/2885/5728/1956/808/1026/6655/5925/5291	CALM1/GRB2/PTEN/EGFR/CALM3/CDKN1A/SOS2/RB1/PIK3CB	9
hsa04620	Toll-like receptor signaling pathway	12/308	102/5868	0.00678624488641003	0.045322421205667	3725/4792/6772/3576/4615/3665/5879/2353/23118/942/5291/7097	JUN/NFKBIA/STAT1/CXCL8/MYD88/IRF7/RAC1/FOS/TAB2/CD86/PIK3CB/TLR2	12
hsa05020	Prion diseases	6/308	35/5868	0.00889340972891312	0.0573471592864398	713/714/5613/1958/5621/712	C1QB/C1QC/PRKX/EGR1/PRNP/C1QA	6
hsa04610	Complement and coagulation cascades	9/308	69/5868	0.00945297613567669	0.058923551245718	728/710/1675/713/714/2162/5329/5328/712	C5AR1/SERPING1/CFD/C1QB/C1QC/F13A1/PLAUR/PLAU/C1QA	9
hsa04621	NOD-like receptor signaling pathway	8/308	58/5868	0.0101731910715495	0.0613673138832181	4792/3576/29108/7128/2920/23118/114548/8767	NFKBIA/CXCL8/PYCARD/TNFAIP3/CXCL2/TAB2/NLRP3/RIPK2	8
hsa04510	Focal adhesion	18/308	200/5868	0.0170576639363736	0.0996807236281834	7422/824/3725/5906/5500/2885/5728/5879/29780/2889/2316/387/1956/10627/6655/1729/5291/2335	VEGFA/CAPN2/JUN/RAP1A/PPP1CB/GRB2/PTEN/RAC1/PARVB/RAPGEF1/FLNA/RHOA/EGFR/MYL12A/SOS2/DIAPH1/PIK3CB/FN1	18
hsa05219	Bladder cancer	6/308	42/5868	0.0211618232896106	0.119916998641127	7422/1890/3576/1956/1026/5925	VEGFA/TYMP/CXCL8/EGFR/CDKN1A/RB1	6
hsa05120	Epithelial cell signaling in Helicobacter pylori infection	8/308	68/5868	0.0250109338345303	0.135595759595144	3725/4792/3576/9296/5879/9550/1956/526	JUN/NFKBIA/CXCL8/ATP6V1F/RAC1/ATP6V1G1/EGFR/ATP6V1B2	8
hsa04650	Natural killer cell mediated cytotoxicity	13/308	136/5868	0.0256077262370023	0.135595759595144	3105/3106/3107/2885/5879/2214/3460/3384/6655/2185/3133/7305/5291	HLA-A/HLA-B/HLA-C/GRB2/RAC1/FCGR3A/IFNGR2/ICAM2/SOS2/PTK2B/HLA-E/TYROBP/PIK3CB	13
hsa03050	Proteasome	6/308	44/5868	0.0261039964996	0.135595759595144	5698/5721/5696/5699/5706/51371	PSMB9/PSME2/PSMB8/PSMB10/PSMC6/POMP	6
hsa05212	Pancreatic cancer	8/308	70/5868	0.0292046029385743	0.14760164187874	7422/6772/5879/5900/5898/1956/5925/5291	VEGFA/STAT1/RAC1/RALGDS/RALA/EGFR/RB1/PIK3CB	8
hsa04670	Leukocyte transendothelial migration	11/308	116/5868	0.0402235706796141	0.192930317067627	7852/653361/5906/4478/5879/3684/387/10627/2185/5291/6387	CXCR4/NCF1/RAP1A/MSN/RAC1/ITGAM/RHOA/MYL12A/PTK2B/PIK3CB/CXCL12	11
hsa04640	Hematopoietic cell lineage	9/308	88/5868	0.0402368040943179	0.192930317067627	3123/3122/928/960/948/290/3684/3575/7037	HLA-DRB1/HLA-DRA/CD9/CD44/CD36/ANPEP/ITGAM/IL7R/TFRC	9
hsa05210	Colorectal cancer	7/308	62/5868	0.0424356480177354	0.198386654482913	3725/5879/2353/5900/387/54205/5291	JUN/RAC1/FOS/RALGDS/RHOA/CYCS/PIK3CB	7
hsa04142	Lysosome	11/308	121/5868	0.0519788836681268	0.237074420632676	6556/1512/54/3423/1509/5476/3074/950/9741/968/5660	SLC11A1/CTSH/ACP5/IDS/CTSD/CTSA/HEXB/SCARB2/LAPTM4A/CD68/PSAP	11
hsa00620	Pyruvate metabolism	5/308	40/5868	0.0563514656354796	0.248758274572568	3939/5315/217/224/3029	LDHA/PKM/ALDH2/ALDH3A2/HAGH	5
hsa04666	Fc gamma R-mediated phagocytosis	9/308	94/5868	0.0572011005701628	0.248758274572568	2213/653361/2934/10093/5879/2214/5291/1072/4082	FCGR2B/NCF1/GSN/ARPC4/RAC1/FCGR3A/PIK3CB/CFL1/MARCKS	9
hsa04144	Endocytosis	16/308	201/5868	0.0618694482532868	0.257769700226847	7852/3105/1601/3106/3107/3134/64750/80230/387/1956/3133/7037/51534/11031/51510/4092	CXCR4/HLA-A/DAB2/HLA-B/HLA-C/HLA-F/SMURF2/RUFY1/RHOA/EGFR/HLA-E/TFRC/VTA1/RAB31/CHMP5/SMAD7	16
hsa05110	Vibrio cholerae infection	6/308	54/5868	0.0620301417658188	0.257769700226847	30001/9296/23480/5613/9550/526	ERO1A/ATP6V1F/SEC61G/PRKX/ATP6V1G1/ATP6V1B2	6
hsa00380	Tryptophan metabolism	5/308	42/5868	0.0670039772835839	0.272385733739787	259307/217/1545/8564/224	IL4I1/ALDH2/CYP1B1/KMO/ALDH3A2	5
hsa04622	RIG-I-like receptor signaling pathway	7/308	71/5868	0.0774378263486245	0.308103692067931	9636/4792/64343/64135/3576/3665/10010	ISG15/NFKBIA/AZI2/IFIH1/CXCL8/IRF7/TANK	7
hsa05200	Pathways in cancer	23/308	326/5868	0.0881231682314695	0.3433131762351	7422/3725/4792/6772/112399/3576/2885/5728/5879/2353/5900/5898/387/54583/1956/9978/54205/6688/1026/6655/5925/5291/2335	VEGFA/JUN/NFKBIA/STAT1/EGLN3/CXCL8/GRB2/PTEN/RAC1/FOS/RALGDS/RALA/RHOA/EGLN1/EGFR/RBX1/CYCS/SPI1/CDKN1A/SOS2/RB1/PIK3CB/FN1	23
hsa04810	Regulation of actin cytoskeleton	16/308	213/5868	0.0926760333034846	0.351845169317012	2934/5305/10093/4478/5500/5879/3684/387/1956/10627/6655/1729/5291/2335/10788/1072	GSN/PIP4K2A/ARPC4/MSN/PPP1CB/RAC1/ITGAM/RHOA/EGFR/MYL12A/SOS2/DIAPH1/PIK3CB/FN1/IQGAP2/CFL1	16
hsa05215	Prostate cancer	8/308	89/5868	0.0940762484804844	0.351845169317012	4792/2885/5728/1956/1026/6655/5925/5291	NFKBIA/GRB2/PTEN/EGFR/CDKN1A/SOS2/RB1/PIK3CB	8
hsa04120	Ubiquitin mediated proteolysis	11/308	135/5868	0.0964340406023899	0.353591482208763	9246/7320/64750/9021/9978/25847/140739/55236/7322/7321/92912	UBE2L6/UBE2B/SMURF2/SOCS3/RBX1/ANAPC13/UBE2F/UBA6/UBE2D2/UBE2D1/UBE2Q2	11
hsa04930	Type II diabetes mellitus	5/308	48/5868	0.105123479095469	0.372523222217129	3099/5315/8660/9021/5291	HK2/PKM/IRS2/SOCS3/PIK3CB	5
hsa04710	Circadian rhythm	3/308	22/5868	0.105581448008063	0.372523222217129	8553/9978/5187	BHLHE40/RBX1/PER1	3
hsa00051	Fructose and mannose metabolism	4/308	36/5868	0.117726120977514	0.407681196718428	3099/2203/226/7167	HK2/FBP1/ALDOA/TPI1	4
hsa05144	Malaria	5/308	51/5868	0.127454498975951	0.429836907447016	3576/948/4615/7097/975	CXCL8/CD36/MYD88/TLR2/CD81	5
hsa04320	Dorso-ventral axis formation	3/308	24/5868	0.12872121292531	0.429836907447016	2885/1956/6655	GRB2/EGFR/SOS2	3
hsa04150	mTOR signaling pathway	5/308	52/5868	0.13534550849121	0.436372587721661	7422/54541/1978/5291/1977	VEGFA/DDIT4/EIF4EBP1/PIK3CB/EIF4E	5
hsa05213	Endometrial cancer	5/308	52/5868	0.13534550849121	0.436372587721661	2885/5728/1956/6655/5291	GRB2/PTEN/EGFR/SOS2/PIK3CB	5
hsa00920	Sulfur metabolism	2/308	13/5868	0.146431209537257	0.464112477685882	9061/9060	PAPSS1/PAPSS2	2
hsa00330	Arginine and proline metabolism	5/308	54/5868	0.151756760662018	0.465221544980286	5033/2752/217/2628/224	P4HA1/GLUL/ALDH2/GATM/ALDH3A2	5
hsa05223	Non-small cell lung cancer	5/308	54/5868	0.151756760662018	0.465221544980286	2885/1956/6655/5925/5291	GRB2/EGFR/SOS2/RB1/PIK3CB	5
hsa04720	Long-term potentiation	6/308	70/5868	0.159908939035573	0.470101051194123	801/2776/5906/5500/5613/808	CALM1/GNAQ/RAP1A/PPP1CB/PRKX/CALM3	6
hsa05100	Bacterial invasion of epithelial cells	6/308	70/5868	0.159908939035573	0.470101051194123	10093/5879/387/3059/5291/2335	ARPC4/RAC1/RHOA/HCLS1/PIK3CB/FN1	6
hsa00030	Pentose phosphate pathway	3/308	27/5868	0.166353432073187	0.470101051194123	2203/226/2821	FBP1/ALDOA/GPI	3
hsa04966	Collecting duct acid secretion	3/308	27/5868	0.166353432073187	0.470101051194123	9296/9550/526	ATP6V1F/ATP6V1G1/ATP6V1B2	3
hsa05130	Pathogenic Escherichia coli infection	5/308	56/5868	0.168955823858822	0.470101051194123	10093/387/3059/3875/4691	ARPC4/RHOA/HCLS1/KRT18/NCL	5
hsa04012	ErbB signaling pathway	7/308	87/5868	0.170945836797863	0.470101051194123	3725/2885/1978/1956/1026/6655/5291	JUN/GRB2/EIF4EBP1/EGFR/CDKN1A/SOS2/PIK3CB	7
hsa04210	Apoptosis	7/308	87/5868	0.170945836797863	0.470101051194123	824/4792/3556/4615/5613/54205/5291	CAPN2/NFKBIA/IL1RAP/MYD88/PRKX/CYCS/PIK3CB	7
hsa05221	Acute myeloid leukemia	5/308	57/5868	0.177830496164695	0.481946417141998	2885/1978/6688/6655/5291	GRB2/EIF4EBP1/SPI1/SOS2/PIK3CB	5
hsa05220	Chronic myeloid leukemia	6/308	73/5868	0.18319191135559	0.489384106049932	4792/2885/1026/6655/5925/5291	NFKBIA/GRB2/CDKN1A/SOS2/RB1/PIK3CB	6
hsa00860	Porphyrin and chlorophyll metabolism	4/308	43/5868	0.187242479673788	0.493159770408426	2495/3162/2512/7389	FTH1/HMOX1/FTL/UROD	4
hsa05146	Amoebiasis	8/308	106/5868	0.191775198902875	0.498082808261632	3576/2776/5613/3684/5291/2335/7097/1992	CXCL8/GNAQ/PRKX/ITGAM/PIK3CB/FN1/TLR2/SERPINB1	8
hsa00020	Citrate cycle (TCA cycle)	3/308	30/5868	0.206726859214652	0.529560584563561	6392/3417/6390	SDHD/IDH1/SDHB	3
hsa00360	Phenylalanine metabolism	2/308	17/5868	0.223437259336116	0.549773256524392	259307/4282	IL4I1/MIF	2
hsa00450	Selenocompound metabolism	2/308	17/5868	0.223437259336116	0.549773256524392	9061/9060	PAPSS1/PAPSS2	2
hsa04614	Renin-angiotensin system	2/308	17/5868	0.223437259336116	0.549773256524392	290/5476	ANPEP/CTSA	2
hsa04060	Cytokine-cytokine receptor interaction	17/308	265/5868	0.227061250486259	0.551434465466629	7852/7422/10673/3576/3556/58191/8764/3460/1956/8742/3575/2920/2921/5473/6357/6387/3597	CXCR4/VEGFA/TNFSF13B/CXCL8/IL1RAP/CXCL16/TNFRSF14/IFNGR2/EGFR/TNFSF12/IL7R/CXCL2/CXCL3/PPBP/CCL13/CXCL12/IL13RA1	17
hsa04114	Oocyte meiosis	8/308	112/5868	0.233774111608028	0.555681889449553	7533/801/5500/5613/5516/9978/25847/808	YWHAH/CALM1/PPP1CB/PRKX/PPP2CB/RBX1/ANAPC13/CALM3	8
hsa00640	Propanoate metabolism	3/308	32/5868	0.23475331158564	0.555681889449553	3939/217/224	LDHA/ALDH2/ALDH3A2	3
hsa04010	MAPK signaling pathway	17/308	268/5868	0.24109488349852	0.561519482199108	3727/1843/3725/5906/2885/5613/5879/2353/2316/1956/10746/23118/4215/6655/1844/3164/1848	JUND/DUSP1/JUN/RAP1A/GRB2/PRKX/RAC1/FOS/FLNA/EGFR/MAP3K2/TAB2/MAP3K3/SOS2/DUSP2/NR4A1/DUSP6	17
hsa00520	Amino sugar and nucleotide sugar metabolism	4/308	48/5868	0.243225016353625	0.561519482199108	3099/2821/3074/2584	HK2/GPI/HEXB/GALK1	4
hsa04530	Tight junction	9/308	132/5868	0.256125180112542	0.572777207038555	8531/1460/5728/387/3059/5516/2035/10627/5872	YBX3/CSNK2B/PTEN/RHOA/HCLS1/PPP2CB/EPB41/MYL12A/RAB13	9
hsa05010	Alzheimer's disease	11/308	167/5868	0.260487467266062	0.572777207038555	348/824/801/2776/6392/2597/6390/54205/808/51107/1329	APOE/CAPN2/CALM1/GNAQ/SDHD/GAPDH/SDHB/CYCS/CALM3/APH1A/COX5B	11
hsa00240	Pyrimidine metabolism	7/308	99/5868	0.262553321605583	0.572777207038555	51251/1890/7378/51727/50484/84265/5434	NT5C3A/TYMP/UPP1/CMPK1/RRM2B/POLR3GL/POLR2E	7
hsa00531	Glycosaminoglycan degradation	2/308	19/5868	0.263087133087498	0.572777207038555	3423/3074	IDS/HEXB	2
hsa04270	Vascular smooth muscle contraction	8/308	116/5868	0.263416255643399	0.572777207038555	801/2776/5500/5613/387/808/3778/4637	CALM1/GNAQ/PPP1CB/PRKX/RHOA/CALM3/KCNMA1/MYL6	8
hsa00480	Glutathione metabolism	4/308	50/5868	0.266605305894327	0.573048186232633	3417/290/50484/2876	IDH1/ANPEP/RRM2B/GPX1	4
hsa04115	p53 signaling pathway	5/308	68/5868	0.284833242383819	0.59674165076362	51246/5728/50484/54205/1026	SHISA5/PTEN/RRM2B/CYCS/CDKN1A	5
hsa04920	Adipocytokine signaling pathway	5/308	68/5868	0.284833242383819	0.59674165076362	4792/2180/948/8660/9021	NFKBIA/ACSL1/CD36/IRS2/SOCS3	5
hsa05222	Small cell lung cancer	6/308	85/5868	0.287201864003881	0.59674165076362	4792/5728/54205/5925/5291/2335	NFKBIA/PTEN/CYCS/RB1/PIK3CB/FN1	6
hsa03320	PPAR signaling pathway	5/308	70/5868	0.30558068659351	0.627951520802048	6319/2180/948/7316/51129	SCD/ACSL1/CD36/UBC/ANGPTL4	5
hsa03018	RNA degradation	5/308	71/5868	0.316039703977128	0.635477684341107	694/2023/2026/10140/11157	BTG1/ENO1/ENO2/TOB1/LSM6	5
hsa05218	Melanoma	5/308	71/5868	0.316039703977128	0.635477684341107	5728/1956/1026/5925/5291	PTEN/EGFR/CDKN1A/RB1/PIK3CB	5
hsa00410	beta-Alanine metabolism	2/308	22/5868	0.322488458532883	0.638704927844198	217/224	ALDH2/ALDH3A2	2
hsa04970	Salivary secretion	6/308	89/5868	0.324475765482346	0.638704927844198	4069/801/2776/5613/808/3778	LYZ/CALM1/GNAQ/PRKX/CALM3/KCNMA1	6
hsa04540	Gap junction	6/308	90/5868	0.333907513557032	0.646152827011613	2776/2885/5613/1956/10746/6655	GNAQ/GRB2/PRKX/EGFR/MAP3K2/SOS2	6
hsa04660	T cell receptor signaling pathway	7/308	108/5868	0.338581462718645	0.646152827011613	3725/4792/2885/2353/387/6655/5291	JUN/NFKBIA/GRB2/FOS/RHOA/SOS2/PIK3CB	7
hsa04623	Cytosolic DNA-sensing pathway	4/308	56/5868	0.338625545706621	0.646152827011613	4792/3665/29108/84265	NFKBIA/IRF7/PYCARD/POLR3GL	4
hsa00562	Inositol phosphate metabolism	4/308	57/5868	0.350761021143747	0.662548595493744	7167/5305/5728/5291	TPI1/PIP4K2A/PTEN/PIK3CB	4
hsa00760	Nicotinate and nicotinamide metabolism	2/308	24/5868	0.361459854072986	0.670909420214503	51251/10135	NT5C3A/NAMPT	2
hsa04360	Axon guidance	8/308	129/5868	0.365750822347689	0.670909420214503	7852/1808/5879/387/2048/1072/6387/8829	CXCR4/DPYSL2/RAC1/RHOA/EPHB2/CFL1/CXCL12/NRP1	8
hsa04141	Protein processing in endoplasmic reticulum	10/308	165/5868	0.365950592844275	0.670909420214503	824/5610/30001/23645/23480/9978/7322/6748/6048/7321	CAPN2/EIF2AK2/ERO1A/PPP1R15A/SEC61G/RBX1/UBE2D2/SSR4/RNF5/UBE2D1	10
hsa04960	Aldosterone-regulated sodium reabsorption	3/308	42/5868	0.380080248142739	0.690048605851381	6446/8660/5291	SGK1/IRS2/PIK3CB	3
hsa04070	Phosphatidylinositol signaling system	5/308	78/5868	0.390043204050884	0.695159232391152	801/5305/5728/808/5291	CALM1/PIP4K2A/PTEN/CALM3/PIK3CB	5
hsa00071	Fatty acid degradation	3/308	43/5868	0.394543080777911	0.695159232391152	2180/217/224	ACSL1/ALDH2/ALDH3A2	3
hsa00053	Ascorbate and aldarate metabolism	2/308	26/5868	0.399569615263837	0.695159232391152	217/224	ALDH2/ALDH3A2	2
hsa00280	Valine, leucine and isoleucine degradation	3/308	44/5868	0.408917195524207	0.695159232391152	259307/217/224	IL4I1/ALDH2/ALDH3A2	3
hsa00310	Lysine degradation	3/308	44/5868	0.408917195524207	0.695159232391152	217/224/29072	ALDH2/ALDH3A2/SETD2	3
hsa03420	Nucleotide excision repair	3/308	44/5868	0.408917195524207	0.695159232391152	9978/6118/7508	RBX1/RPA2/XPC	3
hsa04973	Carbohydrate digestion and absorption	3/308	44/5868	0.408917195524207	0.695159232391152	6518/3099/5291	SLC2A5/HK2/PIK3CB	3
hsa00052	Galactose metabolism	2/308	27/5868	0.418226909919089	0.70458046986369	3099/2584	HK2/GALK1	2
hsa04972	Pancreatic secretion	6/308	101/5868	0.438527727354674	0.72047138178159	2776/4218/5906/5879/387/3778	GNAQ/RAB8A/RAP1A/RAC1/RHOA/KCNMA1	6
hsa00740	Riboflavin metabolism	1/308	11/5868	0.447660909068396	0.72047138178159	54	ACP5	1
hsa04330	Notch signaling pathway	3/308	47/5868	0.451358371412637	0.72047138178159	151636/9541/51107	DTX3L/CIR1/APH1A	3
hsa04350	TGF-beta signaling pathway	5/308	84/5868	0.453143224360611	0.72047138178159	64750/387/5516/9978/4092	SMURF2/RHOA/PPP2CB/RBX1/SMAD7	5
hsa00340	Histidine metabolism	2/308	29/5868	0.454629000268597	0.72047138178159	217/224	ALDH2/ALDH3A2	2
hsa03020	RNA polymerase	2/308	29/5868	0.454629000268597	0.72047138178159	84265/5434	POLR3GL/POLR2E	2
hsa04744	Phototransduction	2/308	29/5868	0.454629000268597	0.72047138178159	801/808	CALM1/CALM3	2
hsa00561	Glycerolipid metabolism	3/308	50/5868	0.492508171510263	0.773941412373271	217/10555/224	ALDH2/AGPAT2/ALDH3A2	3
hsa00040	Pentose and glucuronate interconversions	2/308	32/5868	0.506690101441426	0.783066520409476	217/224	ALDH2/ALDH3A2	2
hsa00250	Alanine, aspartate and glutamate metabolism	2/308	32/5868	0.506690101441426	0.783066520409476	259307/2752	IL4I1/GLUL	2
hsa00603	Glycosphingolipid biosynthesis - globo series	1/308	14/5868	0.530309331032725	0.798948295741024	3074	HEXB	1
hsa05014	Amyotrophic lateral sclerosis (ALS)	3/308	53/5868	0.532084541801974	0.798948295741024	5879/54205/2876	RAC1/CYCS/GPX1	3
hsa04310	Wnt signaling pathway	8/308	150/5868	0.53409911713492	0.798948295741024	3725/1460/5613/5879/387/5516/9978/27101	JUN/CSNK2B/PRKX/RAC1/RHOA/PPP2CB/RBX1/CACYBP	8
hsa04520	Adherens junction	4/308	73/5868	0.538547412878338	0.798948295741024	1460/5879/387/1956	CSNK2B/RAC1/RHOA/EGFR	4
hsa04140	Regulation of autophagy	2/308	34/5868	0.539559360481659	0.798948295741024	11345/64422	GABARAPL2/ATG3	2
hsa04971	Gastric acid secretion	4/308	74/5868	0.549455667345053	0.798948295741024	801/2776/5613/808	CALM1/GNAQ/PRKX/CALM3	4
hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/308	15/5868	0.55502144685813	0.798948295741024	93010	B3GNT7	1
hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/308	15/5868	0.55502144685813	0.798948295741024	3074	HEXB	1
hsa05143	African trypanosomiasis	2/308	35/5868	0.55541860131729	0.798948295741024	2776/4615	GNAQ/MYD88	2
hsa00270	Cysteine and methionine metabolism	2/308	36/5868	0.570887842467785	0.804335934254762	3939/259307	LDHA/IL4I1	2
hsa04130	SNARE interactions in vesicular transport	2/308	36/5868	0.570887842467785	0.804335934254762	10791/6809	VAMP5/STX3	2
hsa04630	Jak-STAT signaling pathway	8/308	155/5868	0.572067803507398	0.804335934254762	6772/2885/9021/3460/3575/6655/5291/3597	STAT1/GRB2/SOCS3/IFNGR2/IL7R/SOS2/PIK3CB/IL13RA1	8
hsa00120	Primary bile acid biosynthesis	1/308	16/5868	0.578437369353892	0.807222299023715	3295	HSD17B4	1
hsa00511	Other glycan degradation	1/308	17/5868	0.600624876230003	0.821544627035742	3074	HEXB	1
hsa04146	Peroxisome	4/308	79/5868	0.601880288256132	0.821544627035742	2180/3295/6648/3417	ACSL1/HSD17B4/SOD2/IDH1	4
hsa04664	Fc epsilon RI signaling pathway	4/308	79/5868	0.601880288256132	0.821544627035742	2885/5879/6655/5291	GRB2/RAC1/SOS2/PIK3CB	4
hsa00230	Purine metabolism	8/308	162/5868	0.622760874598978	0.843886112681223	51251/5315/9061/50484/9060/84265/2987/5434	NT5C3A/PKM/PAPSS1/RRM2B/PAPSS2/POLR3GL/GUK1/POLR2E	8
hsa04110	Cell cycle	6/308	124/5868	0.640428474770564	0.851882889890231	7533/9978/25847/1026/5925/1028	YWHAH/RBX1/ANAPC13/CDKN1A/RB1/CDKN1C	6
hsa00100	Steroid biosynthesis	1/308	19/5868	0.641568272035362	0.851882889890231	6646	SOAT1	1
hsa00350	Tyrosine metabolism	2/308	41/5868	0.642328810024185	0.851882889890231	259307/4282	IL4I1/MIF	2
hsa04512	ECM-receptor interaction	4/308	85/5868	0.65970396213572	0.867567574479168	960/948/2335/375790	CD44/CD36/FN1/AGRN	4
hsa03040	Spliceosome	6/308	127/5868	0.663434027542893	0.867567574479168	6628/51503/10569/51639/3178/11157	SNRPB/CWC15/SLU7/SF3B6/HNRNPA1/LSM6	6
hsa01040	Biosynthesis of unsaturated fatty acids	1/308	21/5868	0.678326432565308	0.869737625391434	6319	SCD	1
hsa04962	Vasopressin-regulated water reabsorption	2/308	44/5868	0.680513252832928	0.869737625391434	8655/5613	DYNLL1/PRKX	2
hsa05012	Parkinson's disease	6/308	130/5868	0.685502251635636	0.869737625391434	9246/6392/120892/6390/54205/1329	UBE2L6/SDHD/LRRK2/SDHB/CYCS/COX5B	6
hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/308	22/5868	0.695271097995423	0.869737625391434	51363	CHST15	1
hsa00190	Oxidative phosphorylation	6/308	132/5868	0.699681618831959	0.869737625391434	6392/9296/9550/6390/526/1329	SDHD/ATP6V1F/ATP6V1G1/SDHB/ATP6V1B2/COX5B	6
hsa04975	Fat digestion and absorption	2/308	46/5868	0.704079326731475	0.869737625391434	948/10555	CD36/AGPAT2	2
hsa00910	Nitrogen metabolism	1/308	23/5868	0.711325922117457	0.869737625391434	2752	GLUL	1
hsa03060	Protein export	1/308	23/5868	0.711325922117457	0.869737625391434	23480	SEC61G	1
hsa03430	Mismatch repair	1/308	23/5868	0.711325922117457	0.869737625391434	6118	RPA2	1
hsa03010	Ribosome	4/308	91/5868	0.711603511683901	0.869737625391434	51065/51121/6166/6170	RPS27L/RPL26L1/RPL36AL/RPL39	4
hsa04977	Vitamin digestion and absorption	1/308	24/5868	0.726537490293304	0.882224095356154	6948	TCN2	1
hsa05016	Huntington's disease	8/308	183/5868	0.753330724751744	0.904558761755414	2776/6648/6392/6390/54205/1329/5434/2876	GNAQ/SOD2/SDHD/SDHB/CYCS/COX5B/POLR2E/GPX1	8
hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/308	26/5868	0.754605170234463	0.904558761755414	84002	B3GNT5	1
hsa00983	Drug metabolism - other enzymes	2/308	52/5868	0.766221406777432	0.911377702790727	1890/7378	TYMP/UPP1	2
hsa04370	VEGF signaling pathway	3/308	76/5868	0.770041053694839	0.911377702790727	7422/5879/5291	VEGFA/RAC1/PIK3CB	3
hsa03440	Homologous recombination	1/308	28/5868	0.779800425993405	0.911582262026771	6118	RPA2	1
hsa00500	Starch and sucrose metabolism	2/308	54/5868	0.784269192988033	0.911582262026771	3099/2821	HK2/GPI	2
hsa04916	Melanogenesis	4/308	101/5868	0.784838204204867	0.911582262026771	801/2776/5613/808	CALM1/GNAQ/PRKX/CALM3	4
hsa03008	Ribosome biogenesis in eukaryotes	3/308	79/5868	0.792364290400848	0.914642730277523	1460/55505/10556	CSNK2B/NOP10/RPP30	3
hsa00140	Steroid hormone biosynthesis	2/308	56/5868	0.801084434949677	0.914950361702508	1545/3292	CYP1B1/HSD17B1	2
hsa00512	Mucin type O-Glycan biosynthesis	1/308	30/5868	0.802416359995783	0.914950361702508	2650	GCNT1	1
hsa03013	RNA transport	6/308	151/5868	0.812798438187886	0.921171563279604	6613/9818/1978/10556/1977/6612	SUMO2/NUP58/EIF4EBP1/RPP30/EIF4E/SUMO3	6
hsa00260	Glycine, serine and threonine metabolism	1/308	32/5868	0.822716254200172	0.922831546170247	2628	GATM	1
hsa00590	Arachidonic acid metabolism	2/308	59/5868	0.82413298508252	0.922831546170247	240/2876	ALOX5/GPX1	2
hsa04020	Calcium signaling pathway	7/308	177/5868	0.82976814736219	0.923610973551962	801/2776/5613/1956/5724/808/2185	CALM1/GNAQ/PRKX/EGFR/PTAFR/CALM3/PTK2B	7
hsa04914	Progesterone-mediated oocyte maturation	3/308	86/5868	0.837508874425137	0.926711003062134	5613/25847/5291	PRKX/ANAPC13/PIK3CB	3
hsa05340	Primary immunodeficiency	1/308	35/5868	0.849334183176704	0.934267601494375	3575	IL7R	1
hsa03030	DNA replication	1/308	36/5868	0.857289792911245	0.937504042540367	6118	RPA2	1
hsa04730	Long-term depression	2/308	70/5868	0.889470639561941	0.966492875115196	2776/5516	GNAQ/PPP2CB	2
hsa04976	Bile secretion	2/308	71/5868	0.894135119758978	0.966492875115196	5613/8714	PRKX/ABCC3	2
hsa02010	ABC transporters	1/308	44/5868	0.907566816082608	0.975373532226711	8714	ABCC3	1
hsa04974	Protein digestion and absorption	2/308	81/5868	0.931696543645196	0.995584306638009	54407/117247	SLC38A2/SLC16A10	2
hsa04742	Taste transduction	1/308	52/5868	0.940167885246777	0.996150484902945	5613	PRKX	1
hsa04340	Hedgehog signaling pathway	1/308	56/5868	0.951873151426096	0.996150484902945	5613	PRKX	1
hsa05414	Dilated cardiomyopathy	2/308	90/5868	0.954398220524991	0.996150484902945	5613/4000	PRKX/LMNA	2
hsa00830	Retinol metabolism	1/308	64/5868	0.968876187110983	0.996150484902945	9249	DHRS3	1
hsa00980	Metabolism of xenobiotics by cytochrome P450	1/308	71/5868	0.978755823067358	0.996150484902945	1545	CYP1B1	1
hsa05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	1/308	74/5868	0.981965791516706	0.996150484902945	4000	LMNA	1
hsa04260	Cardiac muscle contraction	1/308	77/5868	0.984692072568724	0.996150484902945	1329	COX5B	1
hsa00564	Glycerophospholipid metabolism	1/308	80/5868	0.987007348317944	0.996150484902945	10555	AGPAT2	1
hsa03015	mRNA surveillance pathway	1/308	83/5868	0.988973409446038	0.996150484902945	5516	PPP2CB	1
hsa05410	Hypertrophic cardiomyopathy (HCM)	1/308	83/5868	0.988973409446038	0.996150484902945	4000	LMNA	1
hsa04080	Neuroactive ligand-receptor interaction	7/308	272/5868	0.990823476962288	0.996150484902945	2359/140/728/706/1081/2561/5724	FPR3/ADORA3/C5AR1/TSPO/CGA/GABRB2/PTAFR	7
hsa04740	Olfactory transduction	3/308	388/5868	0.999999886818065	0.999999886818065	801/5613/808	CALM1/PRKX/CALM3	3