ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	Count
GO:0048002	antigen processing and presentation of peptide antigen	23/665	62/18722	5.1145126684653e-18	1.44753948204199e-14	FCGR2B/HLA-DQA1/SLC11A1/HLA-DRB1/HLA-DQB1/HLA-A/HLA-DRA/TREM2/HLA-DPB1/HLA-DPA1/B2M/CD74/HLA-B/HLA-C/HLA-DOA/HLA-F/HLA-DMA/PYCARD/CLEC4A/CTSD/HLA-E/IFI30/HLA-DMB	23
GO:0051607	defense response to virus	44/665	265/18722	9.59813478257874e-18	1.44753948204199e-14	ISG15/IFIT3/IFIT1/IFIT2/OAS2/MX2/HERC5/IFITM1/IFI44L/RNASE6/IFI27/DDIT4/MX1/STAT1/NT5C3A/EIF2AK2/OAS1/OAS3/IFIH1/RSAD2/PLSCR1/TRIM22/IFITM3/IFI6/IFITM2/FGL2/IFIT5/BNIP3L/BST2/MYD88/IRF7/BNIP3/PYCARD/TNFAIP3/GBP1/DTX3L/PARP9/IFNGR2/DDX60/OASL/GBP3/TLR2/PHB/SETD2	44
GO:0140546	defense response to symbiont	44/665	265/18722	9.59813478257874e-18	1.44753948204199e-14	ISG15/IFIT3/IFIT1/IFIT2/OAS2/MX2/HERC5/IFITM1/IFI44L/RNASE6/IFI27/DDIT4/MX1/STAT1/NT5C3A/EIF2AK2/OAS1/OAS3/IFIH1/RSAD2/PLSCR1/TRIM22/IFITM3/IFI6/IFITM2/FGL2/IFIT5/BNIP3L/BST2/MYD88/IRF7/BNIP3/PYCARD/TNFAIP3/GBP1/DTX3L/PARP9/IFNGR2/DDX60/OASL/GBP3/TLR2/PHB/SETD2	44
GO:0009615	response to virus	52/665	367/18722	1.16502171592917e-17	1.44753948204199e-14	ISG15/IFIT3/IFIT1/CXCR4/IFIT2/OAS2/MX2/HERC5/IFITM1/IFI44L/RNASE6/IFI27/DDIT4/MX1/STAT1/NT5C3A/EIF2AK2/OAS1/OAS3/IFIH1/IFI44/RSAD2/PLSCR1/TRIM22/IFITM3/IFI6/IFITM2/FGL2/NMI/IFIT5/BNIP3L/BST2/MYD88/IRF7/BNIP3/PYCARD/ENO1/TNFAIP3/GBP1/DTX3L/PARP9/LAMTOR5/IFNGR2/DDX60/OASL/GBP3/IVNS1ABP/TLR2/PHB/CFL1/CXCL12/SETD2	52
GO:0007159	leukocyte cell-cell adhesion	52/665	371/18722	1.87171766087795e-17	1.86048735491268e-14	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/LGALS1/HLA-DPB1/HLA-DPA1/B2M/GPNMB/CD300A/CD74/ADAM8/TNFSF13B/ALOX5/KLF4/CEBPB/FGL2/HLA-DOA/CD44/HLA-DMA/LGALS3/MSN/PYCARD/TNFRSF14/ANXA1/RHOA/LAG3/NFKBIZ/PTAFR/IL7R/WNK1/IL27RA/CD83/S100A8/CD86/SELPLG/DOCK8/HLA-E/GCNT1/IGF2/TFRC/EBI3/HLA-DMB/CXCL12/NLRP3/CD81/SMAD7/RIPK2/PRNP	52
GO:0002478	antigen processing and presentation of exogenous peptide antigen	18/665	38/18722	1.11675858061828e-16	9.25048357612144e-14	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-A/HLA-DRA/HLA-DPB1/HLA-DPA1/B2M/CD74/HLA-DOA/HLA-F/HLA-DMA/CLEC4A/CTSD/HLA-E/IFI30/HLA-DMB	18
GO:1903037	regulation of leukocyte cell-cell adhesion	48/665	336/18722	1.56692188815863e-16	1.11251454059263e-13	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/LGALS1/HLA-DPB1/HLA-DPA1/B2M/GPNMB/CD300A/CD74/ADAM8/TNFSF13B/ALOX5/KLF4/CEBPB/FGL2/HLA-DOA/CD44/HLA-DMA/LGALS3/PYCARD/TNFRSF14/ANXA1/RHOA/LAG3/NFKBIZ/PTAFR/IL7R/WNK1/IL27RA/CD83/CD86/DOCK8/HLA-E/IGF2/TFRC/EBI3/HLA-DMB/CXCL12/NLRP3/CD81/SMAD7/RIPK2/PRNP	48
GO:0022407	regulation of cell-cell adhesion	56/665	448/18722	1.98043149152445e-16	1.23034306410957e-13	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/LGALS1/HLA-DPB1/VEGFA/HLA-DPA1/B2M/CD9/GPNMB/CD300A/CD74/ADAM8/TNFSF13B/ALOX5/KLF4/FXYD5/CEBPB/FGL2/HLA-DOA/MYADM/CD44/HLA-DMA/LGALS3/PYCARD/CITED2/TNFRSF14/PDPN/ANXA1/RHOA/LAG3/NFKBIZ/PTAFR/IL7R/WNK1/IL27RA/PLAUR/CD83/SPI1/CD86/DOCK8/HLA-E/IGF2/TFRC/EBI3/HLA-DMB/CXCL12/NLRP3/CD81/SMAD7/RIPK2/PRNP	56
GO:0019882	antigen processing and presentation	27/665	106/18722	3.63805664738061e-16	2.00901572638685e-13	FCGR2B/HLA-DQA1/SLC11A1/HLA-DRB1/HLA-DQB1/HLA-A/HLA-DRA/TREM2/HLA-DPB1/HLA-DPA1/B2M/CTSH/CD74/HLA-B/HLA-C/FGL2/HLA-DOA/HLA-F/HLA-DMA/PSMB8/PYCARD/CLEC4A/CTSD/HLA-E/IFI30/HLA-DMB/CD68	27
GO:0042110	T cell activation	58/665	487/18722	5.18091319354659e-16	2.57491385719265e-13	FCGR2B/HLA-DQA1/SLC11A1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/LGALS1/HLA-DPB1/HLA-DPA1/GPR183/B2M/GPNMB/CD300A/CD74/ADAM8/ZFP36L2/AZI2/TNFSF13B/JAML/RSAD2/CLEC7A/CEBPB/FGL2/HLA-DOA/CD44/HLA-DMA/GSN/LGALS3/MAFB/MSN/PSMB10/PYCARD/TNFRSF14/ANXA1/RHOA/EGR1/LAG3/NFKBIZ/CLEC4A/IL7R/IL27RA/CD83/SPI1/SOS2/CD86/DOCK8/HLA-E/IGF2/TFRC/EBI3/HLA-DMB/NLRP3/CD81/SMAD7/RIPK2/PRNP	58
GO:0016032	viral process	52/665	415/18722	2.23867531405621e-15	1.01147421007812e-12	ISG15/IFIT1/CXCR4/HLA-DRB1/OAS2/LGALS1/IFITM1/APOE/IFI27/MX1/CD74/JUN/STAT1/EIF2AK2/OAS1/OAS3/IFIH1/CXCL8/RSAD2/PLSCR1/TRIM22/IFITM3/IFITM2/IFIT5/SSB/BST2/ZFP36/GSN/IRF7/N4BP1/LY6E/ANPEP/TNFRSF14/PARP9/LAMTOR5/EGFR/KPNA3/LARP7/OASL/CD86/SELPLG/TFRC/SCARB2/MDFIC/PHB/ZBED1/VTA1/RSF1/CFL1/CHMP5/CD81/NRP1	52
GO:0045785	positive regulation of cell adhesion	53/665	437/18722	4.71397366730232e-15	1.7694933167553e-12	HLA-DQA1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/LGALS1/HLA-DPB1/VEGFA/HLA-DPA1/B2M/LIMS1/CD74/ADAM8/TNFSF13B/ALOX5/S100A10/HLA-DOA/MYADM/CD44/CD36/HLA-DMA/PYCARD/CITED2/RAC1/TNFRSF14/PDPN/ANXA1/FLNA/RHOA/NFKBIZ/PTAFR/IL7R/IL27RA/PLAUR/CD83/STX3/CD86/PTK2B/DOCK8/HLA-E/IGF2/TFRC/FN1/EBI3/RIN2/HLA-DMB/CXCL12/NLRP3/CD81/SMAD7/RIPK2/NRP1	53
GO:0002697	regulation of immune effector process	46/665	339/18722	4.95202082141272e-15	1.7694933167553e-12	FCGR2B/HLA-DRB1/IL4I1/HLA-A/HLA-DRA/TREM2/B2M/CD300A/CD74/RSAD2/HLA-B/CLEC7A/FGL2/SERPING1/NCF1/AHR/HLA-F/CD36/BST2/CADM1/RAP1A/LGALS3/HMOX1/TNFRSF14/ANXA1/ITGAM/GPI/LAG3/NFKBIZ/PTAFR/IL7R/DDX60/IL27RA/GRN/SPI1/CD86/HLA-E/TYROBP/TFRC/EPHB2/PHB/HLA-DMB/NLRP3/CD81/SMAD7/RIPK2	46
GO:0001819	positive regulation of cytokine production	55/665	467/18722	4.9844882162121e-15	1.7694933167553e-12	ISG15/SLC11A1/OAS2/HLA-A/TREM2/HLA-DPB1/HLA-DPA1/B2M/CD74/ADAM8/SULF2/STAT1/EIF2AK2/OAS1/OAS3/IFIH1/RSAD2/IL1RAP/CLEC7A/CEBPB/C5AR1/MIF/LILRA5/HLA-F/CD36/CADM1/MYD88/GAPDH/IRF7/PYCARD/HMOX1/TNFRSF14/ANXA1/EGR1/IRF8/LAMTOR5/AKIRIN2/PTAFR/LRRK2/IL27RA/CD83/CD58/CD86/AGPAT2/HLA-E/TYROBP/EPHB2/CYP1B1/EBI3/TLR2/PHB/NLRP3/CD81/SETD2/RIPK2	55
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	16/665	34/18722	6.53345528681462e-15	2.16475151836458e-12	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/TREM2/HLA-DPB1/HLA-DPA1/B2M/CD74/HLA-DOA/HLA-DMA/PYCARD/CTSD/IFI30/HLA-DMB	16
GO:0019884	antigen processing and presentation of exogenous antigen	18/665	47/18722	1.12617546941072e-14	3.49818255185705e-12	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-A/HLA-DRA/HLA-DPB1/HLA-DPA1/B2M/CD74/HLA-DOA/HLA-F/HLA-DMA/CLEC4A/CTSD/HLA-E/IFI30/HLA-DMB	18
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	16/665	36/18722	2.02736499768811e-14	5.92706119912349e-12	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/TREM2/HLA-DPB1/HLA-DPA1/B2M/CD74/HLA-DOA/HLA-DMA/PYCARD/CTSD/IFI30/HLA-DMB	16
GO:0070661	leukocyte proliferation	43/665	318/18722	4.47236842845537e-14	1.23487061607907e-11	FCGR2B/SLC11A1/HLA-DRB1/IL4I1/HLA-A/TREM2/HLA-DPB1/HLA-DPA1/GPR183/GPNMB/CD300A/CD74/AZI2/TNFSF13B/CEBPB/MIF/AHR/BST2/IRS2/MYD88/LGALS3/MSN/PSMB10/PYCARD/TNFAIP3/TNFRSF14/ANXA1/IL7R/IL27RA/CDKN1A/SOS2/CD86/DOCK8/HLA-E/IGF2/TYROBP/TFRC/EPHB2/EBI3/HLA-DMB/CD81/RIPK2/PRNP	43
GO:0050867	positive regulation of cell activation	50/665	420/18722	6.02023720365671e-14	1.57476731064073e-11	HLA-DQA1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/TREM2/LGALS1/HLA-DPB1/JUND/HLA-DPA1/GPR183/B2M/CD74/ADAM8/TNFSF13B/CLEC7A/HLA-DOA/MIF/LILRA5/HLA-F/HLA-DMA/IRS2/HAMP/MYD88/PYCARD/TNFRSF14/ANXA1/ITGAM/RHOA/NFKBIZ/PTAFR/IL7R/LRRK2/IL27RA/CD83/MMP14/CDKN1A/CD86/DOCK8/HLA-E/IGF2/TYROBP/TFRC/EPHB2/EBI3/HLA-DMB/NLRP3/CD81/RIPK2	50
GO:0002696	positive regulation of leukocyte activation	49/665	409/18722	8.50267175458253e-14	2.11291393101376e-11	HLA-DQA1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/TREM2/LGALS1/HLA-DPB1/JUND/HLA-DPA1/GPR183/B2M/CD74/ADAM8/TNFSF13B/CLEC7A/HLA-DOA/MIF/HLA-F/HLA-DMA/IRS2/HAMP/MYD88/PYCARD/TNFRSF14/ANXA1/ITGAM/RHOA/NFKBIZ/PTAFR/IL7R/LRRK2/IL27RA/CD83/MMP14/CDKN1A/CD86/DOCK8/HLA-E/IGF2/TYROBP/TFRC/EPHB2/EBI3/HLA-DMB/NLRP3/CD81/RIPK2	49
GO:0022409	positive regulation of cell-cell adhesion	40/665	284/18722	9.05534665792477e-14	2.1430987090422e-11	HLA-DQA1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/LGALS1/HLA-DPB1/HLA-DPA1/B2M/CD74/ADAM8/TNFSF13B/ALOX5/HLA-DOA/CD44/HLA-DMA/PYCARD/CITED2/TNFRSF14/PDPN/ANXA1/RHOA/NFKBIZ/PTAFR/IL7R/IL27RA/PLAUR/CD83/CD86/DOCK8/HLA-E/IGF2/TFRC/EBI3/HLA-DMB/NLRP3/CD81/SMAD7/RIPK2	40
GO:0050900	leukocyte migration	46/665	369/18722	1.18237376886498e-13	2.50361313107348e-11	CXCR4/TREM2/VEGFA/GPR183/CD9/CD300A/DUSP1/CD74/ADAM8/JAML/ALOX5/CXCL8/MYO1G/C5AR1/ECM1/MIF/CXCL16/MYD88/LGALS3/TREM1/RIN3/MSN/PYCARD/HMOX1/RAC1/TNFRSF14/ANXA1/RHOA/PLEC/PTAFR/WNK1/CXCL2/IL27RA/S100A8/MMP14/SPI1/CXCL3/SELPLG/PTK2B/DOCK8/GCNT1/PPBP/CCL13/CXCL12/NLRP3/CD81	46
GO:0002831	regulation of response to biotic stimulus	43/665	327/18722	1.19825727572085e-13	2.50361313107348e-11	FCGR2B/ISG15/IFIT1/HLA-DRB1/IL4I1/HLA-A/TREM2/HERC5/APOE/ADAM8/STAT1/OAS1/OAS3/HLA-B/PLSCR1/CLEC7A/FGL2/NMI/CARD16/SERPING1/NCF1/AHR/HLA-F/CD36/CADM1/IRF7/N4BP1/PYCARD/TNFAIP3/DTX3L/PARP9/IFI35/LAG3/TRIB1/AKIRIN2/USP18/DDX60/GRN/SPI1/OASL/HLA-E/TYROBP/RIPK2	43
GO:0050792	regulation of viral process	30/665	164/18722	1.20898823230912e-13	2.50361313107348e-11	ISG15/IFIT1/CXCR4/HLA-DRB1/OAS2/LGALS1/IFITM1/MX1/CD74/STAT1/EIF2AK2/OAS1/OAS3/IFIH1/CXCL8/RSAD2/PLSCR1/TRIM22/IFITM3/IFITM2/IFIT5/BST2/ZFP36/GSN/N4BP1/LY6E/LARP7/OASL/MDFIC/RSF1	30
GO:0046651	lymphocyte proliferation	40/665	288/18722	1.44578467005436e-13	2.83663699293695e-11	FCGR2B/SLC11A1/HLA-DRB1/IL4I1/HLA-A/HLA-DPB1/HLA-DPA1/GPR183/GPNMB/CD300A/CD74/AZI2/TNFSF13B/CEBPB/MIF/AHR/IRS2/MYD88/LGALS3/MSN/PSMB10/PYCARD/TNFRSF14/ANXA1/IL7R/IL27RA/CDKN1A/SOS2/CD86/DOCK8/HLA-E/IGF2/TYROBP/TFRC/EPHB2/EBI3/HLA-DMB/CD81/RIPK2/PRNP	40
GO:0050863	regulation of T cell activation	43/665	329/18722	1.48395496612396e-13	2.83663699293695e-11	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/LGALS1/HLA-DPB1/HLA-DPA1/B2M/GPNMB/CD300A/CD74/ADAM8/TNFSF13B/CEBPB/FGL2/HLA-DOA/HLA-DMA/LGALS3/PYCARD/TNFRSF14/ANXA1/RHOA/LAG3/NFKBIZ/IL7R/IL27RA/CD83/SOS2/CD86/DOCK8/HLA-E/IGF2/TFRC/EBI3/HLA-DMB/NLRP3/CD81/SMAD7/RIPK2/PRNP	43
GO:0019058	viral life cycle	42/665	317/18722	1.79882143459755e-13	3.31116389998142e-11	ISG15/IFIT1/CXCR4/HLA-DRB1/OAS2/LGALS1/IFITM1/APOE/IFI27/MX1/CD74/EIF2AK2/OAS1/OAS3/IFIH1/CXCL8/RSAD2/PLSCR1/TRIM22/IFITM3/IFITM2/IFIT5/BST2/GSN/N4BP1/LY6E/ANPEP/TNFRSF14/LAMTOR5/EGFR/KPNA3/OASL/CD86/SELPLG/TFRC/SCARB2/PHB/ZBED1/VTA1/CHMP5/CD81/NRP1	42
GO:0032943	mononuclear cell proliferation	40/665	291/18722	2.04149566938688e-13	3.54170933438764e-11	FCGR2B/SLC11A1/HLA-DRB1/IL4I1/HLA-A/HLA-DPB1/HLA-DPA1/GPR183/GPNMB/CD300A/CD74/AZI2/TNFSF13B/CEBPB/MIF/AHR/IRS2/MYD88/LGALS3/MSN/PSMB10/PYCARD/TNFRSF14/ANXA1/IL7R/IL27RA/CDKN1A/SOS2/CD86/DOCK8/HLA-E/IGF2/TYROBP/TFRC/EPHB2/EBI3/HLA-DMB/CD81/RIPK2/PRNP	40
GO:1903039	positive regulation of leukocyte cell-cell adhesion	36/665	239/18722	2.06659095970305e-13	3.54170933438764e-11	HLA-DQA1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/LGALS1/HLA-DPB1/HLA-DPA1/B2M/CD74/ADAM8/TNFSF13B/ALOX5/HLA-DOA/CD44/HLA-DMA/PYCARD/TNFRSF14/ANXA1/RHOA/NFKBIZ/PTAFR/IL7R/IL27RA/CD83/CD86/DOCK8/HLA-E/IGF2/TFRC/EBI3/HLA-DMB/NLRP3/CD81/RIPK2	36
GO:0002237	response to molecule of bacterial origin	45/665	363/18722	2.69466221936996e-13	4.46415707675623e-11	FCGR2B/VIM/SLC11A1/TREM2/JUND/B2M/CAPN2/JUN/NFKBIA/CXCL8/ACP5/CEBPB/ADM/CARD16/C5AR1/SOD2/TSPO/CD36/ZFP36/HAMP/MYD88/PYCARD/TNFAIP3/FOS/RHOA/LITAF/IRF8/TRIB1/AKIRIN2/PTAFR/CXCL2/TAB2/S100A8/HNRNPA0/SPI1/CXCL3/CD86/PPBP/KMO/TLR2/NR4A1/CHMP5/NLRP3/CD68/RIPK2	45
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	14/665	30/18722	3.82148110684374e-13	6.12669712935915e-11	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/HLA-DPB1/HLA-DPA1/B2M/CD74/HLA-DOA/HLA-DMA/CTSD/IFI30/HLA-DMB	14
GO:0070663	regulation of leukocyte proliferation	36/665	245/18722	4.43467913268572e-13	6.88761102795251e-11	FCGR2B/HLA-DRB1/IL4I1/HLA-A/HLA-DPB1/HLA-DPA1/GPR183/GPNMB/CD300A/CD74/TNFSF13B/CEBPB/MIF/AHR/BST2/IRS2/MYD88/LGALS3/PYCARD/TNFAIP3/TNFRSF14/ANXA1/IL27RA/CDKN1A/SOS2/CD86/HLA-E/IGF2/TYROBP/TFRC/EPHB2/EBI3/HLA-DMB/CD81/RIPK2/PRNP	36
GO:0032496	response to lipopolysaccharide	43/665	343/18722	6.30781242519494e-13	9.49994780400571e-11	VIM/SLC11A1/TREM2/JUND/CAPN2/JUN/NFKBIA/CXCL8/ACP5/CEBPB/ADM/CARD16/C5AR1/SOD2/TSPO/CD36/ZFP36/HAMP/MYD88/PYCARD/TNFAIP3/FOS/RHOA/LITAF/IRF8/TRIB1/AKIRIN2/PTAFR/CXCL2/TAB2/S100A8/HNRNPA0/SPI1/CXCL3/CD86/PPBP/KMO/TLR2/NR4A1/CHMP5/NLRP3/CD68/RIPK2	43
GO:0002683	negative regulation of immune system process	49/665	434/18722	8.1014248264266e-13	1.16143639172504e-10	FCGR2B/ISG15/HLA-DRB1/IL4I1/HLA-A/TSC22D3/TREM2/GPNMB/CD300A/DUSP1/CD74/OAS1/OAS3/HLA-B/CEBPB/MERTK/FGL2/HLA-DOA/NMI/SERPING1/MIF/AHR/HLA-F/BST2/LGALS3/MAFB/C1QC/RIN3/TNFAIP3/HMOX1/GBP1/TNFRSF14/ANXA1/SAMSN1/LAG3/TRIB1/IL7R/USP18/IL27RA/GRN/SPI1/CD86/HLA-E/TYROBP/CXCL12/CD68/SMAD7/PRNP/GPX1	49
GO:0048525	negative regulation of viral process	22/665	92/18722	8.17912951919043e-13	1.16143639172504e-10	ISG15/IFIT1/OAS2/IFITM1/MX1/STAT1/EIF2AK2/OAS1/OAS3/IFIH1/RSAD2/PLSCR1/IFITM3/IFITM2/IFIT5/BST2/ZFP36/GSN/N4BP1/LY6E/LARP7/OASL	22
GO:0050670	regulation of lymphocyte proliferation	34/665	225/18722	8.8609920299664e-13	1.22330917747036e-10	FCGR2B/HLA-DRB1/IL4I1/HLA-A/HLA-DPB1/HLA-DPA1/GPR183/GPNMB/CD300A/CD74/TNFSF13B/CEBPB/MIF/AHR/IRS2/MYD88/LGALS3/PYCARD/TNFRSF14/ANXA1/IL27RA/CDKN1A/SOS2/CD86/HLA-E/IGF2/TYROBP/TFRC/EPHB2/EBI3/HLA-DMB/CD81/RIPK2/PRNP	34
GO:0070482	response to oxygen levels	43/665	347/18722	9.39230495648479e-13	1.26161501712782e-10	CXCR4/LDHA/TREM2/VEGFA/DDIT4/CAPN2/ADAM8/NDRG1/HK2/EGLN3/PGK1/ERO1A/NR4A2/ADM/CARD16/SOD2/BNIP3L/ANG/NAMPT/BNIP3/ENO1/FAM162A/CITED2/PTEN/HMOX1/ATP6V1G1/PDPN/EIF4EBP1/RHOA/EGR1/LMNA/EGLN1/PLK3/MMP14/PLAU/CDKN1A/ACVRL1/PTK2B/KCNMA1/TLR2/ANGPTL4/CPEB2/CXCL12	43
GO:0032944	regulation of mononuclear cell proliferation	34/665	227/18722	1.14732898332462e-12	1.50058553871668e-10	FCGR2B/HLA-DRB1/IL4I1/HLA-A/HLA-DPB1/HLA-DPA1/GPR183/GPNMB/CD300A/CD74/TNFSF13B/CEBPB/MIF/AHR/IRS2/MYD88/LGALS3/PYCARD/TNFRSF14/ANXA1/IL27RA/CDKN1A/SOS2/CD86/HLA-E/IGF2/TYROBP/TFRC/EPHB2/EBI3/HLA-DMB/CD81/RIPK2/PRNP	34
GO:0050870	positive regulation of T cell activation	33/665	216/18722	1.4102795700697e-12	1.79720242647344e-10	HLA-DQA1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/LGALS1/HLA-DPB1/HLA-DPA1/B2M/CD74/ADAM8/TNFSF13B/HLA-DOA/HLA-DMA/PYCARD/TNFRSF14/ANXA1/RHOA/NFKBIZ/IL7R/IL27RA/CD83/CD86/DOCK8/HLA-E/IGF2/TFRC/EBI3/HLA-DMB/NLRP3/CD81/RIPK2	33
GO:0019221	cytokine-mediated signaling pathway	51/665	472/18722	1.47748886558847e-12	1.83577991549367e-10	ISG15/CXCR4/OAS2/TREM2/IFITM1/IFI27/MX1/LIMS1/CD74/NFKBIA/STAT1/OAS1/TNFSF13B/OAS3/CXCL8/IL1RAP/IFITM3/IFITM2/ACSL1/NMI/CARD16/CSNK2B/ECM1/LILRA5/CD44/PLP2/MYD88/IRF7/PYCARD/TNFAIP3/TNFRSF14/PARP9/EGR1/IFNGR2/IL7R/KRT18/USP18/WNK1/CXCL2/IL27RA/SPI1/OASL/CXCL3/AGPAT2/PTK2B/PPBP/CCL13/EBI3/CXCL12/IL13RA1/RIPK2	51
GO:1903706	regulation of hemopoiesis	44/665	367/18722	1.60058100884826e-12	1.94021649121362e-10	FCGR2B/ISG15/HLA-DRB1/IL4I1/HLA-DRA/TREM2/B2M/CD74/ADAM8/JUN/NFKBIA/ZFP36L2/STAT1/EVI2B/HLA-B/CEBPB/FGL2/HLA-DOA/ZFP36/KLF10/IRF7/MAFB/C1QC/RASSF2/FOS/ANXA1/RHOA/HCLS1/LAG3/NFKBIZ/TRIB1/IL7R/CD83/MMP14/SPI1/SOS2/CD86/PTK2B/TYROBP/RB1/HAX1/NLRP3/SMAD7/RIPK2	44
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	43/665	356/18722	2.24668038765401e-12	2.65857179205725e-10	FCGR2B/HLA-DQA1/SLC11A1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/TREM2/HLA-DPB1/HLA-DPA1/B2M/CTSH/CD74/TNFSF13B/RSAD2/MYO1G/HLA-B/CLEC7A/HLA-DOA/SERPING1/AHR/HLA-F/HLA-DMA/C1QB/MYD88/IRF7/C1QC/TNFAIP3/ANXA1/NFKBIZ/IL7R/IL27RA/HLA-E/TFRC/EBI3/PHB/HLA-DMB/NLRP3/CD81/SMAD7/RIPK2/C1QA	43
GO:0002699	positive regulation of immune effector process	34/665	235/18722	3.12849941671406e-12	3.61596327931834e-10	HLA-DRB1/HLA-A/HLA-DRA/TREM2/B2M/CD300A/CD74/RSAD2/HLA-B/CLEC7A/HLA-F/CD36/CADM1/RAP1A/HMOX1/TNFRSF14/ANXA1/ITGAM/GPI/LAG3/NFKBIZ/PTAFR/DDX60/SPI1/CD86/HLA-E/TYROBP/TFRC/EPHB2/PHB/HLA-DMB/NLRP3/CD81/RIPK2	34
GO:0051251	positive regulation of lymphocyte activation	43/665	362/18722	3.94886898364375e-12	4.46042701107033e-10	HLA-DQA1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/LGALS1/HLA-DPB1/HLA-DPA1/GPR183/B2M/CD74/ADAM8/TNFSF13B/CLEC7A/HLA-DOA/MIF/HLA-F/HLA-DMA/IRS2/MYD88/PYCARD/TNFRSF14/ANXA1/RHOA/NFKBIZ/IL7R/IL27RA/CD83/MMP14/CDKN1A/CD86/DOCK8/HLA-E/IGF2/TYROBP/TFRC/EPHB2/EBI3/HLA-DMB/NLRP3/CD81/RIPK2	43
GO:1902105	regulation of leukocyte differentiation	37/665	279/18722	4.9616536757517e-12	5.36777147795455e-10	FCGR2B/HLA-DRB1/IL4I1/HLA-DRA/TREM2/CD74/ADAM8/JUN/ZFP36L2/EVI2B/HLA-B/CEBPB/FGL2/HLA-DOA/KLF10/IRF7/MAFB/C1QC/RASSF2/FOS/ANXA1/RHOA/HCLS1/LAG3/NFKBIZ/TRIB1/IL7R/CD83/MMP14/SOS2/CD86/TYROBP/RB1/HAX1/NLRP3/SMAD7/RIPK2	37
GO:0045071	negative regulation of viral genome replication	17/665	56/18722	5.01176310292564e-12	5.36777147795455e-10	ISG15/IFIT1/OAS2/IFITM1/MX1/EIF2AK2/OAS1/OAS3/IFIH1/RSAD2/PLSCR1/IFITM3/IFITM2/IFIT5/BST2/N4BP1/OASL	17
GO:0001666	response to hypoxia	39/665	307/18722	5.07616216225078e-12	5.36777147795455e-10	CXCR4/LDHA/TREM2/VEGFA/DDIT4/CAPN2/ADAM8/NDRG1/HK2/EGLN3/PGK1/ERO1A/NR4A2/ADM/CARD16/SOD2/BNIP3L/ANG/BNIP3/ENO1/FAM162A/CITED2/PTEN/HMOX1/EIF4EBP1/RHOA/EGR1/LMNA/EGLN1/PLK3/MMP14/PLAU/ACVRL1/PTK2B/KCNMA1/TLR2/ANGPTL4/CPEB2/CXCL12	39
GO:0036293	response to decreased oxygen levels	40/665	322/18722	5.51135145745796e-12	5.7065451549096e-10	CXCR4/LDHA/TREM2/VEGFA/DDIT4/CAPN2/ADAM8/NDRG1/HK2/EGLN3/PGK1/ERO1A/NR4A2/ADM/CARD16/SOD2/BNIP3L/ANG/NAMPT/BNIP3/ENO1/FAM162A/CITED2/PTEN/HMOX1/EIF4EBP1/RHOA/EGR1/LMNA/EGLN1/PLK3/MMP14/PLAU/ACVRL1/PTK2B/KCNMA1/TLR2/ANGPTL4/CPEB2/CXCL12	40
GO:0007249	I-kappaB kinase/NF-kappaB signaling	37/665	281/18722	6.15792806179795e-12	6.24589846268078e-10	S100A4/HLA-DRB1/TREM2/LGALS1/CD74/NFKBIA/STAT1/AZI2/TRIM22/CLEC7A/CARD16/IFIT5/ECM1/CD36/TERF2IP/BST2/MYD88/GAPDH/PYCARD/TNFAIP3/SHISA5/HMOX1/FLNA/RHOA/LITAF/LAMTOR5/RHOC/TAB2/TANK/MAP3K3/SQSTM1/TFRC/CARD19/TLR2/PER1/ATP2C1/RIPK2	37
GO:0002819	regulation of adaptive immune response	29/665	183/18722	1.2956280864462e-11	1.28785431792753e-09	FCGR2B/SLC11A1/HLA-DRB1/IL4I1/HLA-A/HLA-DRA/TREM2/B2M/TNFSF13B/RSAD2/HLA-B/CLEC7A/AHR/HLA-F/IRF7/PYCARD/TNFAIP3/TNFRSF14/ANXA1/SAMSN1/NFKBIZ/IL7R/IL27RA/HLA-E/TFRC/NLRP3/CD81/SMAD7/RIPK2	29
GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	34/665	249/18722	1.62400939445489e-11	1.58261307655702e-09	S100A4/HLA-DRB1/TREM2/LGALS1/CD74/STAT1/TRIM22/CLEC7A/CARD16/IFIT5/ECM1/CD36/TERF2IP/BST2/MYD88/GAPDH/PYCARD/TNFAIP3/SHISA5/HMOX1/FLNA/RHOA/LITAF/LAMTOR5/RHOC/TAB2/TANK/MAP3K3/SQSTM1/TFRC/CARD19/PER1/ATP2C1/RIPK2	34
GO:0002399	MHC class II protein complex assembly	10/665	16/18722	1.97475168987717e-11	1.85179545258293e-09	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/HLA-DPB1/HLA-DPA1/B2M/HLA-DOA/HLA-DMA/HLA-DMB	10
GO:0002503	peptide antigen assembly with MHC class II protein complex	10/665	16/18722	1.97475168987717e-11	1.85179545258293e-09	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/HLA-DPB1/HLA-DPA1/B2M/HLA-DOA/HLA-DMA/HLA-DMB	10
GO:0071216	cellular response to biotic stimulus	33/665	246/18722	5.24977785148767e-11	4.83173998553588e-09	FCGR2B/VIM/TREM2/CAPN2/TXNIP/NFKBIA/CXCL8/CLEC7A/CEBPB/CARD16/TSPO/CD36/ZFP36/HAMP/MYD88/PYCARD/TNFAIP3/RHOA/LITAF/IRF8/TRIB1/PTAFR/CXCL2/SPI1/CXCL3/CD86/PPBP/KMO/TLR2/CHMP5/NLRP3/CD68/RIPK2	33
GO:0050777	negative regulation of immune response	29/665	194/18722	5.6051762813335e-11	5.065041112405e-09	FCGR2B/ISG15/HLA-DRB1/IL4I1/HLA-A/TREM2/CD300A/OAS1/OAS3/HLA-B/FGL2/NMI/SERPING1/AHR/HLA-F/LGALS3/TNFAIP3/HMOX1/TNFRSF14/ANXA1/SAMSN1/IL7R/USP18/IL27RA/GRN/SPI1/HLA-E/SMAD7/GPX1	29
GO:0002443	leukocyte mediated immunity	46/665	440/18722	5.92121355697043e-11	5.25507703181126e-09	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/TREM2/HLA-DPB1/HLA-DPA1/B2M/CD300A/CTSH/CD74/RSAD2/MYO1G/HLA-B/CLEC7A/HLA-DOA/SERPING1/AHR/HLA-F/BST2/HLA-DMA/CADM1/C1QB/MYD88/TREM1/IRF7/C1QC/HMOX1/ITGAM/LAG3/PTAFR/IL7R/IL27RA/KIF5B/SPI1/HLA-E/TYROBP/TFRC/HLA-DMB/NLRP3/CD81/SMAD7/C1QA	46
GO:0002366	leukocyte activation involved in immune response	35/665	275/18722	6.06722498613987e-11	5.2901944177395e-09	FCGR2B/SLC11A1/HLA-DRB1/HLA-DRA/TREM2/LGALS1/GPR183/CD300A/CD74/CLEC7A/FGL2/NMI/HLA-F/MYD88/LGALS3/PYCARD/HMOX1/ANXA1/ITGAM/IRF8/IFI35/NFKBIZ/PTAFR/IL27RA/GRN/SPI1/CD86/PTK2B/TYROBP/TFRC/HLA-DMB/NLRP3/CD81/SMAD7/RIPK2	35
GO:0071219	cellular response to molecule of bacterial origin	31/665	221/18722	6.43338628050932e-11	5.51274651967782e-09	FCGR2B/VIM/TREM2/CAPN2/NFKBIA/CXCL8/CEBPB/CARD16/TSPO/CD36/ZFP36/HAMP/MYD88/PYCARD/TNFAIP3/RHOA/LITAF/IRF8/TRIB1/PTAFR/CXCL2/SPI1/CXCL3/CD86/PPBP/KMO/TLR2/CHMP5/NLRP3/CD68/RIPK2	31
GO:0002685	regulation of leukocyte migration	30/665	210/18722	8.2774570781937e-11	6.97270536925808e-09	TREM2/VEGFA/CD9/CD300A/DUSP1/CD74/ADAM8/CXCL8/C5AR1/ECM1/MIF/MYD88/LGALS3/RIN3/MSN/PYCARD/HMOX1/RAC1/TNFRSF14/ANXA1/RHOA/PTAFR/WNK1/IL27RA/MMP14/SPI1/PTK2B/DOCK8/CXCL12/CD81	30
GO:0002263	cell activation involved in immune response	35/665	279/18722	9.10006579545178e-11	7.53788783389922e-09	FCGR2B/SLC11A1/HLA-DRB1/HLA-DRA/TREM2/LGALS1/GPR183/CD300A/CD74/CLEC7A/FGL2/NMI/HLA-F/MYD88/LGALS3/PYCARD/HMOX1/ANXA1/ITGAM/IRF8/IFI35/NFKBIZ/PTAFR/IL27RA/GRN/SPI1/CD86/PTK2B/TYROBP/TFRC/HLA-DMB/NLRP3/CD81/SMAD7/RIPK2	35
GO:0002501	peptide antigen assembly with MHC protein complex	10/665	18/18722	1.01157641905314e-10	8.02840520339262e-09	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/HLA-DPB1/HLA-DPA1/B2M/HLA-DOA/HLA-DMA/HLA-DMB	10
GO:0071706	tumor necrosis factor superfamily cytokine production	28/665	186/18722	1.01768516662723e-10	8.02840520339262e-09	OAS2/TREM2/GPNMB/ADAM8/OAS1/OAS3/IFIH1/ACP5/CLEC7A/ERRFI1/MIF/LILRA5/TSPO/CD36/ZFP36/MYD88/PYCARD/TNFAIP3/CLEC4A/PTAFR/LRRK2/IL27RA/CD86/HLA-E/TYROBP/EPHB2/TLR2/RIPK2	28
GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	28/665	186/18722	1.01768516662723e-10	8.02840520339262e-09	OAS2/TREM2/GPNMB/ADAM8/OAS1/OAS3/IFIH1/ACP5/CLEC7A/ERRFI1/MIF/LILRA5/TSPO/CD36/ZFP36/MYD88/PYCARD/TNFAIP3/CLEC4A/PTAFR/LRRK2/IL27RA/CD86/HLA-E/TYROBP/EPHB2/TLR2/RIPK2	28
GO:0002396	MHC protein complex assembly	10/665	19/18722	2.06771748059901e-10	1.60571185602767e-08	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/HLA-DPB1/HLA-DPA1/B2M/HLA-DOA/HLA-DMA/HLA-DMB	10
GO:1903131	mononuclear cell differentiation	44/665	426/18722	2.31497226550936e-10	1.77006340916639e-08	FCGR2B/HLA-DRB1/IL4I1/HLA-DRA/TREM2/LGALS1/VEGFA/GPR183/B2M/CD74/ADAM8/JUN/ZFP36L2/AZI2/TNFSF13B/RSAD2/HLA-B/CEBPB/MERTK/FGL2/HLA-DOA/KLF6/NFIL3/IRF7/MAFB/IRF2BP2/ANXA1/RHOA/EGR1/IRF8/LAG3/NFKBIZ/IL7R/CD83/MMP14/TPD52/SPI1/SOS2/CD86/PTK2B/CMTM7/NLRP3/SMAD7/RIPK2	44
GO:0044403	biological process involved in symbiotic interaction	35/665	290/18722	2.66164299101965e-10	2.00429782808601e-08	IFIT1/CXCR4/HLA-DRB1/SAP30/LGALS1/IFITM1/APOE/IFI27/CD74/JUN/CXCL8/PLSCR1/TRIM22/IFITM3/IFITM2/GSN/MYD88/GAPDH/TREM1/LY6E/ANPEP/TNFRSF14/EGFR/KPNA3/CD86/SELPLG/TFRC/FN1/SCARB2/PHB/ZBED1/CFL1/CD81/GPX1/NRP1	35
GO:0071222	cellular response to lipopolysaccharide	29/665	209/18722	3.47261489065454e-10	2.57595462784374e-08	VIM/CAPN2/NFKBIA/CXCL8/CEBPB/CARD16/TSPO/CD36/ZFP36/HAMP/MYD88/PYCARD/TNFAIP3/RHOA/LITAF/IRF8/TRIB1/PTAFR/CXCL2/SPI1/CXCL3/CD86/PPBP/KMO/TLR2/CHMP5/NLRP3/CD68/RIPK2	29
GO:1903900	regulation of viral life cycle	24/665	148/18722	4.69101167127588e-10	3.42857764797663e-08	ISG15/IFIT1/HLA-DRB1/OAS2/LGALS1/IFITM1/MX1/CD74/EIF2AK2/OAS1/OAS3/IFIH1/CXCL8/RSAD2/PLSCR1/TRIM22/IFITM3/IFITM2/IFIT5/BST2/GSN/N4BP1/LY6E/OASL	24
GO:0032103	positive regulation of response to external stimulus	43/665	427/18722	8.21841501215816e-10	5.91964095803276e-08	NUPR1/CXCR4/TREM2/VEGFA/CD74/ADAM8/NFKBIA/CXCL8/PLSCR1/CLEC7A/CEBPB/NMI/C5AR1/LILRA5/HLA-F/CADM1/IRF7/PYCARD/RAC1/ALOX5AP/PARP9/FLNA/IFI35/LAG3/NFKBIZ/EGFR/AKIRIN2/LRRK2/DDX60/WNK1/GRN/S100A8/STX3/SPI1/OASL/PTK2B/HLA-E/TYROBP/TLR2/CXCL12/CD81/RIPK2/NRP1	43
GO:0045069	regulation of viral genome replication	18/665	85/18722	8.41038823311328e-10	5.97137564551043e-08	ISG15/IFIT1/OAS2/IFITM1/MX1/EIF2AK2/OAS1/OAS3/IFIH1/CXCL8/RSAD2/PLSCR1/IFITM3/IFITM2/IFIT5/BST2/N4BP1/OASL	18
GO:0045088	regulation of innate immune response	29/665	218/18722	9.53035659328382e-10	6.55102860963234e-08	FCGR2B/ISG15/HLA-A/TREM2/APOE/ADAM8/OAS1/OAS3/HLA-B/PLSCR1/CLEC7A/NMI/SERPING1/NCF1/HLA-F/CADM1/IRF7/N4BP1/PYCARD/TNFAIP3/PARP9/IFI35/LAG3/AKIRIN2/USP18/GRN/SPI1/HLA-E/TYROBP	29
GO:0034341	response to interferon-gamma	23/665	141/18722	9.58739555353922e-10	6.55102860963234e-08	VIM/SLC11A1/HLA-DPA1/IFITM1/CD74/STAT1/IFITM3/IFITM2/NMI/BST2/CXCL16/GAPDH/RAB20/GBP1/PARP9/IRF8/IFNGR2/GBP4/KIF5B/CD58/GBP3/CCL13/TLR2	23
GO:0030099	myeloid cell differentiation	40/665	381/18722	9.62223518115012e-10	6.55102860963234e-08	ISG15/HLA-DRB1/TREM2/VEGFA/GPR183/B2M/CD74/JUN/NFKBIA/STAT1/EVI2B/CEBPB/SNX10/ZFP36/PIP4K2A/KLF10/IRF7/MAFB/C1QC/JUNB/ABI1/CITED2/RASSF2/PRKX/FOS/KLF2/HCLS1/IRF8/TRIB1/SPI1/PTK2B/ANXA2/TYROBP/TFRC/RB1/ZNF385A/TLR2/HAX1/OSCAR/CD81	40
GO:0034340	response to type I interferon	15/665	58/18722	1.11339682392866e-09	7.47781380395333e-08	ISG15/IFIT1/OAS2/IFITM1/IFI27/MX1/STAT1/OAS1/OAS3/IFITM3/IFITM2/MYD88/IRF7/USP18/SETD2	15
GO:0019079	viral genome replication	22/665	131/18722	1.25745365991996e-09	8.3327262530696e-08	ISG15/IFIT1/OAS2/IFITM1/IFI27/MX1/EIF2AK2/OAS1/OAS3/IFIH1/CXCL8/RSAD2/PLSCR1/IFITM3/IFITM2/IFIT5/BST2/N4BP1/LAMTOR5/OASL/PHB/ZBED1	22
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	25/665	168/18722	1.31395789892088e-09	8.53685487524744e-08	FCGR2B/SLC11A1/HLA-DRB1/IL4I1/HLA-A/HLA-DRA/TREM2/B2M/TNFSF13B/RSAD2/HLA-B/CLEC7A/AHR/HLA-F/TNFAIP3/ANXA1/NFKBIZ/IL7R/IL27RA/HLA-E/TFRC/NLRP3/CD81/SMAD7/RIPK2	25
GO:0032640	tumor necrosis factor production	26/665	181/18722	1.33978808907304e-09	8.53685487524744e-08	OAS2/TREM2/GPNMB/OAS1/OAS3/IFIH1/ACP5/CLEC7A/ERRFI1/MIF/LILRA5/TSPO/CD36/ZFP36/MYD88/PYCARD/TNFAIP3/CLEC4A/PTAFR/LRRK2/IL27RA/HLA-E/TYROBP/EPHB2/TLR2/RIPK2	26
GO:0032680	regulation of tumor necrosis factor production	26/665	181/18722	1.33978808907304e-09	8.53685487524744e-08	OAS2/TREM2/GPNMB/OAS1/OAS3/IFIH1/ACP5/CLEC7A/ERRFI1/MIF/LILRA5/TSPO/CD36/ZFP36/MYD88/PYCARD/TNFAIP3/CLEC4A/PTAFR/LRRK2/IL27RA/HLA-E/TYROBP/EPHB2/TLR2/RIPK2	26
GO:0002573	myeloid leukocyte differentiation	28/665	208/18722	1.41384109913434e-09	8.89467121860464e-08	HLA-DRB1/TREM2/VEGFA/GPR183/CD74/JUN/EVI2B/CEBPB/SNX10/KLF10/IRF7/MAFB/C1QC/JUNB/CITED2/RASSF2/FOS/HCLS1/TRIB1/SPI1/ANXA2/TYROBP/TFRC/RB1/TLR2/HAX1/OSCAR/CD81	28
GO:1902107	positive regulation of leukocyte differentiation	24/665	157/18722	1.61378004102061e-09	9.90183556033631e-08	HLA-DRB1/IL4I1/HLA-DRA/TREM2/CD74/ADAM8/JUN/EVI2B/KLF10/FOS/ANXA1/RHOA/HCLS1/NFKBIZ/TRIB1/IL7R/CD83/MMP14/CD86/TYROBP/RB1/HAX1/NLRP3/RIPK2	24
GO:1903708	positive regulation of hemopoiesis	24/665	157/18722	1.61378004102061e-09	9.90183556033631e-08	HLA-DRB1/IL4I1/HLA-DRA/TREM2/CD74/ADAM8/JUN/EVI2B/KLF10/FOS/ANXA1/RHOA/HCLS1/NFKBIZ/TRIB1/IL7R/CD83/MMP14/CD86/TYROBP/RB1/HAX1/NLRP3/RIPK2	24
GO:0042098	T cell proliferation	27/665	199/18722	2.33466237574166e-09	1.41503317163854e-07	SLC11A1/HLA-DRB1/IL4I1/HLA-A/HLA-DPB1/HLA-DPA1/GPNMB/TNFSF13B/CEBPB/LGALS3/MSN/PSMB10/PYCARD/TNFRSF14/ANXA1/IL27RA/SOS2/CD86/DOCK8/HLA-E/IGF2/TFRC/EBI3/HLA-DMB/CD81/RIPK2/PRNP	27
GO:0070997	neuron death	38/665	361/18722	2.36558692216223e-09	1.41650204857184e-07	FCGR2B/NUPR1/TREM2/GPNMB/APOE/DDIT4/CAPN2/ADAM8/JUN/EGLN3/CEBPB/NR4A2/C5AR1/SOD2/HLA-F/NAMPT/GAPDH/BNIP3/FAM162A/MCL1/HMOX1/FOS/ITGAM/RHOA/EGR1/GPI/GABRB2/LRRK2/GRN/PTK2B/TYROBP/RB1/AKT1S1/KMO/PRNP/GPX1/C1QA/NRP1	38
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	26/665	186/18722	2.42807067669544e-09	1.43660848371147e-07	S100A4/HLA-DRB1/LGALS1/CD74/TRIM22/CLEC7A/CARD16/IFIT5/ECM1/CD36/TERF2IP/BST2/MYD88/GAPDH/SHISA5/HMOX1/FLNA/RHOA/LITAF/LAMTOR5/RHOC/TAB2/MAP3K3/TFRC/ATP2C1/RIPK2	26
GO:0050671	positive regulation of lymphocyte proliferation	22/665	137/18722	3.00677807521965e-09	1.75808082751078e-07	HLA-A/HLA-DPB1/HLA-DPA1/GPR183/CD74/TNFSF13B/MIF/IRS2/MYD88/PYCARD/ANXA1/IL27RA/CDKN1A/CD86/HLA-E/IGF2/TFRC/EPHB2/EBI3/HLA-DMB/CD81/RIPK2	22
GO:0097193	intrinsic apoptotic signaling pathway	33/665	288/18722	3.28595565301626e-09	1.89828482646224e-07	NUPR1/TREM2/DDIT4/CD74/CRIP1/IFI6/CEBPB/YBX3/ERO1A/PPP1R15A/SOD2/RPS27L/MIF/CD44/SKIL/BNIP3/PYCARD/ENO1/SHISA5/MCL1/HMOX1/RRM2B/LRRK2/PLAUR/S100A8/CDKN1A/ZNF385A/GRINA/CYP1B1/IVNS1ABP/CXCL12/BCL2A1/GPX1	33
GO:0070665	positive regulation of leukocyte proliferation	23/665	150/18722	3.32295331795202e-09	1.89828482646224e-07	HLA-A/HLA-DPB1/HLA-DPA1/GPR183/CD74/TNFSF13B/MIF/BST2/IRS2/MYD88/PYCARD/ANXA1/IL27RA/CDKN1A/CD86/HLA-E/IGF2/TFRC/EPHB2/EBI3/HLA-DMB/CD81/RIPK2	23
GO:0002449	lymphocyte mediated immunity	37/665	350/18722	3.42851584097696e-09	1.93200222432025e-07	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/IL4I1/HLA-A/HLA-DRA/TREM2/HLA-DPB1/HLA-DPA1/B2M/CTSH/CD74/RSAD2/MYO1G/HLA-B/HLA-DOA/SERPING1/AHR/HLA-F/HLA-DMA/CADM1/C1QB/MYD88/IRF7/C1QC/LAG3/IL7R/IL27RA/KIF5B/HLA-E/TFRC/HLA-DMB/NLRP3/CD81/SMAD7/C1QA	37
GO:0032946	positive regulation of mononuclear cell proliferation	22/665	138/18722	3.45972229304834e-09	1.93200222432025e-07	HLA-A/HLA-DPB1/HLA-DPA1/GPR183/CD74/TNFSF13B/MIF/IRS2/MYD88/PYCARD/ANXA1/IL27RA/CDKN1A/CD86/HLA-E/IGF2/TFRC/EPHB2/EBI3/HLA-DMB/CD81/RIPK2	22
GO:0044409	entry into host	23/665	151/18722	3.79139059767778e-09	2.09369014116207e-07	CXCR4/HLA-DRB1/LGALS1/IFITM1/CD74/CXCL8/PLSCR1/TRIM22/IFITM3/IFITM2/GSN/LY6E/ANPEP/TNFRSF14/EGFR/KPNA3/CD86/SELPLG/TFRC/SCARB2/PHB/CD81/NRP1	23
GO:0001818	negative regulation of cytokine production	37/665	357/18722	5.87396896519004e-09	3.20809074252687e-07	FCGR2B/SLC11A1/HLA-DRB1/SRGN/TREM2/GPNMB/OAS1/OAS3/KLF4/ACP5/MERTK/NMI/ERRFI1/CARD16/LILRA5/TSPO/HLA-F/BST2/ZFP36/N4BP1/PYCARD/TNFAIP3/HMOX1/RAC1/GBP1/ANXA1/KLF2/LAG3/CLEC4A/IL27RA/CD83/TYROBP/FN1/SERPINB1/NLRP3/SMAD7/PRNP	37
GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	19/665	107/18722	6.49776905206648e-09	3.51020784660548e-07	OAS2/ADAM8/OAS1/OAS3/IFIH1/CLEC7A/MIF/LILRA5/CD36/MYD88/PYCARD/PTAFR/LRRK2/CD86/HLA-E/TYROBP/EPHB2/TLR2/RIPK2	19
GO:0046718	viral entry into host cell	22/665	144/18722	7.80861104029748e-09	4.17298891078263e-07	CXCR4/HLA-DRB1/LGALS1/IFITM1/CD74/PLSCR1/TRIM22/IFITM3/IFITM2/GSN/LY6E/ANPEP/TNFRSF14/EGFR/KPNA3/CD86/SELPLG/TFRC/SCARB2/PHB/CD81/NRP1	22
GO:0002703	regulation of leukocyte mediated immunity	28/665	226/18722	9.26569180152055e-09	4.89898811208054e-07	FCGR2B/HLA-DRB1/IL4I1/HLA-A/HLA-DRA/TREM2/B2M/CD300A/RSAD2/HLA-B/CLEC7A/AHR/HLA-F/BST2/CADM1/HMOX1/ITGAM/LAG3/PTAFR/IL7R/IL27RA/SPI1/HLA-E/TYROBP/TFRC/NLRP3/CD81/SMAD7	28
GO:0007162	negative regulation of cell adhesion	33/665	303/18722	1.17153297320195e-08	6.12896723875123e-07	FCGR2B/HLA-DRB1/IL4I1/LGALS1/VEGFA/CD9/GPNMB/CD300A/DUSP1/CD74/KLF4/FXYD5/CEBPB/FGL2/MYADM/LGALS3/PTEN/GBP1/TNFRSF14/ANXA1/RHOA/LAG3/WNK1/MMP14/SPI1/CD86/ACVRL1/TGFBI/EPHB2/CYP1B1/CXCL12/SMAD7/PRNP	33
GO:0002468	dendritic cell antigen processing and presentation	8/665	15/18722	1.25406977638446e-08	6.49242373815705e-07	FCGR2B/SLC11A1/HLA-DRB1/HLA-DRA/CD74/FGL2/CLEC4A/CD68	8
GO:0042326	negative regulation of phosphorylation	38/665	385/18722	1.39228104841511e-08	7.13364619651867e-07	NUPR1/APOE/DDIT4/CD300A/DUSP1/CALM1/SH3BP5/FBP1/MYADM/ERRFI1/GNAQ/DYNLL1/TERF2IP/IRS2/UBE2B/PIP4K2A/PYCARD/TNFAIP3/RASSF2/PTEN/SOCS3/RGS2/SAMSN1/TRIB1/PLEC/AIDA/LRRK2/WNK1/CALM3/CDKN1A/RB1/PIK3CB/EPHB2/AKT1S1/CDKN1C/SMAD7/PRNP/DUSP6	38
GO:0002821	positive regulation of adaptive immune response	19/665	112/18722	1.42060256662189e-08	7.204484445011e-07	SLC11A1/HLA-DRB1/HLA-A/HLA-DRA/TREM2/B2M/TNFSF13B/RSAD2/HLA-B/CLEC7A/HLA-F/PYCARD/NFKBIZ/IL27RA/HLA-E/TFRC/NLRP3/CD81/RIPK2	19
GO:0042060	wound healing	40/665	422/18722	1.79989867191624e-08	9.03585494891284e-07	SLC11A1/CXCR4/VEGFA/CD9/APOE/JAML/ALOX5/TIMP1/PLSCR1/CLEC7A/MERTK/GNAQ/SERPING1/CD44/CD36/TNFAIP3/CLIC1/PTEN/HMOX1/PDPN/ANXA1/FLNA/RHOA/F13A1/EGFR/PLEC/RHOC/DST/PLAUR/MYL12A/S100A8/PLAU/CDKN1A/ACVRL1/VKORC1/ANXA2/PIK3CB/EPHB2/FN1/GPX1	40
GO:0030098	lymphocyte differentiation	37/665	374/18722	2.03564141764679e-08	1.01171378457045e-06	FCGR2B/HLA-DRB1/IL4I1/HLA-DRA/LGALS1/GPR183/B2M/CD74/ADAM8/ZFP36L2/TNFSF13B/RSAD2/MERTK/FGL2/HLA-DOA/KLF6/NFIL3/MAFB/IRF2BP2/ANXA1/RHOA/EGR1/IRF8/LAG3/NFKBIZ/IL7R/CD83/MMP14/TPD52/SPI1/SOS2/CD86/PTK2B/CMTM7/NLRP3/SMAD7/RIPK2	37
GO:0045936	negative regulation of phosphate metabolic process	41/665	441/18722	2.06113605416254e-08	1.01424219694929e-06	NUPR1/APOE/DDIT4/CD300A/DUSP1/APOC1/CALM1/SH3BP5/FBP1/MYADM/ERRFI1/GNAQ/PPP1R15A/DYNLL1/TERF2IP/IRS2/UBE2B/PIP4K2A/LGALS3/PYCARD/TNFAIP3/RASSF2/PTEN/SOCS3/RGS2/SAMSN1/TRIB1/PLEC/AIDA/LRRK2/WNK1/CALM3/CDKN1A/RB1/PIK3CB/EPHB2/AKT1S1/CDKN1C/SMAD7/PRNP/DUSP6	41
GO:0097529	myeloid leukocyte migration	27/665	220/18722	2.0872767503375e-08	1.01703582835072e-06	TREM2/VEGFA/CD9/CD300A/DUSP1/CD74/ADAM8/JAML/CXCL8/C5AR1/MIF/MYD88/LGALS3/TREM1/RIN3/RAC1/ANXA1/CXCL2/S100A8/MMP14/SPI1/CXCL3/PTK2B/PPBP/CCL13/CXCL12/CD81	27
GO:0010563	negative regulation of phosphorus metabolic process	41/665	442/18722	2.19707271462242e-08	1.06014091181295e-06	NUPR1/APOE/DDIT4/CD300A/DUSP1/APOC1/CALM1/SH3BP5/FBP1/MYADM/ERRFI1/GNAQ/PPP1R15A/DYNLL1/TERF2IP/IRS2/UBE2B/PIP4K2A/LGALS3/PYCARD/TNFAIP3/RASSF2/PTEN/SOCS3/RGS2/SAMSN1/TRIB1/PLEC/AIDA/LRRK2/WNK1/CALM3/CDKN1A/RB1/PIK3CB/EPHB2/AKT1S1/CDKN1C/SMAD7/PRNP/DUSP6	41
GO:0071357	cellular response to type I interferon	13/665	52/18722	2.25774417827044e-08	1.07894120826962e-06	ISG15/IFIT1/OAS2/IFITM1/IFI27/STAT1/OAS1/OAS3/IFITM3/IFITM2/MYD88/IRF7/USP18	13
GO:0000302	response to reactive oxygen species	27/665	222/18722	2.53191783877876e-08	1.19844111035528e-06	LDHA/APOE/CAPN2/DUSP1/TXNIP/JUN/STAT1/KLF4/SOD2/NCF1/CD36/BNIP3/TNFAIP3/HMOX1/FOS/ANXA1/KLF2/PPP2CB/RHOB/EGFR/RBX1/LRRK2/PLK3/TXN/PTK2B/CYP1B1/GPX1	27
GO:0002274	myeloid leukocyte activation	27/665	223/18722	2.78598762823993e-08	1.30626023701438e-06	FCGR2B/SLC11A1/TREM2/JUND/CD300A/CD74/NDRG1/CXCL8/PLSCR1/NMI/C5AR1/MIF/HAMP/NAMPT/MYD88/PYCARD/HMOX1/ITGAM/IFI35/IFNGR2/PTAFR/LRRK2/GRN/SPI1/TYROBP/TLR2/C1QA	27
GO:0050866	negative regulation of cell activation	26/665	210/18722	3.17874980308483e-08	1.47648472161978e-06	FCGR2B/HLA-DRB1/IL4I1/TREM2/CD9/GPNMB/APOE/CD300A/CD74/CEBPB/MERTK/FGL2/HLA-F/LGALS3/TNFAIP3/HMOX1/TNFRSF14/ANXA1/SAMSN1/LAG3/GRN/SPI1/CD86/TYROBP/SMAD7/PRNP	26
GO:0042116	macrophage activation	18/665	106/18722	3.3528472730387e-08	1.54293064324096e-06	FCGR2B/SLC11A1/TREM2/JUND/CD74/NMI/C5AR1/MIF/HAMP/NAMPT/ITGAM/IFI35/IFNGR2/LRRK2/GRN/TYROBP/TLR2/C1QA	18
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	18/665	107/18722	3.89953566203844e-08	1.7780451596634e-06	SLC11A1/HLA-DRB1/HLA-A/HLA-DRA/TREM2/B2M/TNFSF13B/RSAD2/HLA-B/CLEC7A/HLA-F/NFKBIZ/IL27RA/HLA-E/TFRC/NLRP3/CD81/RIPK2	18
GO:0042129	regulation of T cell proliferation	23/665	171/18722	4.22189759293608e-08	1.90753009426294e-06	HLA-DRB1/IL4I1/HLA-A/HLA-DPB1/HLA-DPA1/GPNMB/TNFSF13B/CEBPB/LGALS3/PYCARD/TNFRSF14/ANXA1/IL27RA/SOS2/CD86/HLA-E/IGF2/TFRC/EBI3/HLA-DMB/CD81/RIPK2/PRNP	23
GO:0030595	leukocyte chemotaxis	27/665	230/18722	5.35005685099011e-08	2.39547590535323e-06	CXCR4/VEGFA/GPR183/DUSP1/CD74/ADAM8/JAML/ALOX5/CXCL8/C5AR1/MIF/CXCL16/LGALS3/TREM1/RIN3/RAC1/ANXA1/PLEC/WNK1/CXCL2/S100A8/SPI1/CXCL3/PTK2B/PPBP/CCL13/CXCL12	27
GO:0045862	positive regulation of proteolysis	36/665	372/18722	5.55812330610572e-08	2.46641721708441e-06	NUPR1/TREM2/APOE/CTSH/ADAM8/DAB2/EGLN3/CLEC7A/SUMO2/PSME2/RPS27L/GSN/PYCARD/ENO1/FAM162A/PTEN/RHOA/TRIB1/AKIRIN2/RBX1/LRRK2/CTSD/CYCS/TANK/GRN/S100A8/PSMC6/PLK3/MMP14/PTK2B/APH1A/FN1/GRAMD4/NLRP3/SMAD7/RIPK2	36
GO:0002698	negative regulation of immune effector process	18/665	110/18722	6.06746037479727e-08	2.6686086781188e-06	FCGR2B/IL4I1/HLA-A/CD300A/HLA-B/FGL2/SERPING1/AHR/HLA-F/BST2/LGALS3/HMOX1/ANXA1/IL7R/GRN/SPI1/HLA-E/SMAD7	18
GO:0036294	cellular response to decreased oxygen levels	22/665	161/18722	6.22405456909309e-08	2.69039773132848e-06	TREM2/VEGFA/ADAM8/NDRG1/EGLN3/PGK1/ERO1A/CARD16/BNIP3L/NAMPT/BNIP3/ENO1/FAM162A/CITED2/PTEN/HMOX1/EIF4EBP1/EGR1/LMNA/EGLN1/PLK3/CPEB2	22
GO:0072678	T cell migration	14/665	66/18722	6.22526638033753e-08	2.69039773132848e-06	GPR183/ADAM8/MYO1G/ECM1/CXCL16/MSN/PYCARD/TNFRSF14/RHOA/PLEC/WNK1/IL27RA/DOCK8/CXCL12	14
GO:0052126	movement in host environment	23/665	175/18722	6.52604259616685e-08	2.79607169853011e-06	CXCR4/HLA-DRB1/LGALS1/IFITM1/CD74/CXCL8/PLSCR1/TRIM22/IFITM3/IFITM2/GSN/LY6E/ANPEP/TNFRSF14/EGFR/KPNA3/CD86/SELPLG/TFRC/SCARB2/PHB/CD81/NRP1	23
GO:0052547	regulation of peptidase activity	41/665	461/18722	7.08458285131949e-08	3.00943391205623e-06	VEGFA/PSMB9/CTSH/TIMP1/EGLN3/KLF4/CLEC7A/IFI6/CARD16/ECM1/PSME2/SERPING1/RPS27L/CD44/BST2/PSMB8/GSN/GAPDH/PYCARD/CSTB/FAM162A/RHOA/GPI/LAMTOR5/AKIRIN2/CTSD/CYCS/PLAUR/TANK/GRN/S100A8/APH1A/ANXA2/FN1/GRAMD4/NR4A1/SERPINB1/NLRP3/RIPK2/PRNP/GPX1	41
GO:0071453	cellular response to oxygen levels	23/665	177/18722	8.07172742401334e-08	3.39970214384291e-06	TREM2/VEGFA/ADAM8/NDRG1/EGLN3/PGK1/ERO1A/CARD16/BNIP3L/NAMPT/BNIP3/ENO1/FAM162A/CITED2/PTEN/HMOX1/ATP6V1G1/EIF4EBP1/EGR1/LMNA/EGLN1/PLK3/CPEB2	23
GO:0071456	cellular response to hypoxia	21/665	151/18722	9.11098381916735e-08	3.78253617204356e-06	TREM2/VEGFA/ADAM8/NDRG1/EGLN3/PGK1/ERO1A/CARD16/BNIP3L/BNIP3/ENO1/FAM162A/CITED2/PTEN/HMOX1/EIF4EBP1/EGR1/LMNA/EGLN1/PLK3/CPEB2	21
GO:0046939	nucleotide phosphorylation	17/665	101/18722	9.20899148525695e-08	3.78253617204356e-06	NUPR1/LDHA/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/TPI1/CMPK1/GAPDH/ENO1/GPI/ENO2/PGAM1/GUK1/GALK1	17
GO:0050830	defense response to Gram-positive bacterium	17/665	101/18722	9.20899148525695e-08	3.78253617204356e-06	HLA-A/RNASE6/LYZ/ACP5/C5AR1/CD36/ANG/MYD88/PYCARD/TNFRSF14/IL7R/GBP4/IL27RA/HLA-E/TLR2/RIPK2/RPL39	17
GO:0051098	regulation of binding	35/665	363/18722	9.32017638622164e-08	3.79682595405914e-06	IFIT1/IFIT2/B2M/APOE/JUN/NFKBIA/DAB2/CALM1/KLF4/S100A10/CARD16/CSNK2B/CLIC2/MAPRE1/HMOX1/DTX3L/PARP9/PPP2CB/LAMTOR5/EPB41/LRRK2/PHLDA2/PLAUR/CALM3/EDF1/C4orf3/CDKN1A/TXN/CAMK1/ANXA2/RB1/SUMO3/RSF1/RIPK2/NRP1	35
GO:0032760	positive regulation of tumor necrosis factor production	17/665	103/18722	1.23883797903626e-07	5.00571118358554e-06	OAS2/OAS1/OAS3/IFIH1/CLEC7A/MIF/LILRA5/CD36/MYD88/PYCARD/PTAFR/LRRK2/HLA-E/TYROBP/EPHB2/TLR2/RIPK2	17
GO:0060337	type I interferon signaling pathway	12/665	50/18722	1.28594237997213e-07	5.1541400229528e-06	ISG15/OAS2/IFITM1/IFI27/STAT1/OAS1/OAS3/IFITM3/IFITM2/MYD88/IRF7/USP18	12
GO:0002483	antigen processing and presentation of endogenous peptide antigen	8/665	19/18722	1.29804258947076e-07	5.16101733573573e-06	HLA-DRB1/HLA-A/HLA-DRA/B2M/HLA-B/HLA-C/HLA-F/HLA-E	8
GO:0071674	mononuclear cell migration	24/665	196/18722	1.32481661434312e-07	5.22566553435341e-06	CXCR4/GPR183/DUSP1/ADAM8/JAML/ALOX5/MYO1G/C5AR1/ECM1/CXCL16/LGALS3/MSN/PYCARD/TNFRSF14/ANXA1/RHOA/PLEC/WNK1/IL27RA/SPI1/PTK2B/DOCK8/CCL13/CXCL12	24
GO:1901214	regulation of neuron death	32/665	319/18722	1.34795769897732e-07	5.27507855426558e-06	FCGR2B/NUPR1/TREM2/GPNMB/APOE/DDIT4/CAPN2/ADAM8/JUN/EGLN3/CEBPB/NR4A2/C5AR1/SOD2/HLA-F/MCL1/HMOX1/FOS/ITGAM/RHOA/EGR1/GPI/GABRB2/LRRK2/GRN/PTK2B/TYROBP/AKT1S1/KMO/PRNP/C1QA/NRP1	32
GO:0050727	regulation of inflammatory response	36/665	386/18722	1.40399862353225e-07	5.4514634054338e-06	FCGR2B/NUPR1/HLA-DRB1/TREM2/APOE/ADAM8/NFKBIA/ALOX5/KLF4/ACP5/CEBPB/NMI/LILRA5/NCF1/ZFP36/HAMP/MYD88/PYCARD/TNFAIP3/SOCS3/ALOX5AP/ANXA1/IFI35/NFKBIZ/EGFR/LRRK2/USP18/GRN/S100A8/HLA-E/SIGLEC10/RB1/TLR2/NLRP3/CD81/GPX1	36
GO:0006096	glycolytic process	15/665	81/18722	1.42861148197754e-07	5.50403028327781e-06	NUPR1/LDHA/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/TPI1/GAPDH/ENO1/GPI/ENO2/PGAM1/GALK1	15
GO:0019883	antigen processing and presentation of endogenous antigen	9/665	26/18722	1.54918295864374e-07	5.92264561881493e-06	HLA-DRB1/HLA-A/HLA-DRA/B2M/CD74/HLA-B/HLA-C/HLA-F/HLA-E	9
GO:0006757	ATP generation from ADP	15/665	82/18722	1.69186922047354e-07	6.41877101202555e-06	NUPR1/LDHA/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/TPI1/GAPDH/ENO1/GPI/ENO2/PGAM1/GALK1	15
GO:2001233	regulation of apoptotic signaling pathway	34/665	356/18722	1.78558025487908e-07	6.72298020208258e-06	NUPR1/TREM2/CTSH/CD74/IFI6/YBX3/NR4A2/ATF3/SOD2/MIF/CD44/SKIL/LGALS3/PYCARD/ENO1/PEA15/TNFAIP3/MCL1/PTEN/HMOX1/RRM2B/LMNA/TNFSF12/LRRK2/PLAUR/S100A8/G0S2/RB1/ZNF385A/GRINA/IVNS1ABP/CXCL12/GPX1/NRP1	34
GO:0010038	response to metal ion	35/665	373/18722	1.80897164922116e-07	6.75984142603699e-06	JUND/B2M/DUSP1/TXNIP/JUN/NDRG1/CALM1/PLSCR1/CRIP1/FBP1/SOD2/NCF1/TSPO/HAMP/FOSB/MT1X/BNIP3/JUNB/PTEN/HMOX1/ALOX5AP/FOS/PPP2CB/GPI/EGFR/LRRK2/WNK1/CALM3/S100A8/CACYBP/PTK2B/KCNMA1/HSD17B1/PRNP/C1QA	35
GO:0009185	ribonucleoside diphosphate metabolic process	17/665	106/18722	1.90583272878831e-07	7.06864825528203e-06	NUPR1/LDHA/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/TPI1/CMPK1/GAPDH/ENO1/GPI/ENO2/PGAM1/GUK1/GALK1	17
GO:0002440	production of molecular mediator of immune response	31/665	308/18722	1.96365189603237e-07	7.22914809131916e-06	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-A/HLA-DRA/HLA-DPB1/HLA-DPA1/B2M/CD74/RSAD2/CLEC7A/HLA-DOA/HLA-F/CD36/BST2/HLA-DMA/TREM1/HMOX1/TNFRSF14/GPI/IL27RA/CD86/HLA-E/TFRC/EPHB2/PHB/HLA-DMB/NLRP3/CD81/SMAD7	31
GO:0002577	regulation of antigen processing and presentation	8/665	20/18722	2.09616345502587e-07	7.66024439079306e-06	FCGR2B/SLC11A1/TREM2/CD74/FGL2/HLA-DOA/PYCARD/CD68	8
GO:0051402	neuron apoptotic process	27/665	246/18722	2.14453655410622e-07	7.77981509044375e-06	NUPR1/TREM2/APOE/ADAM8/JUN/EGLN3/CEBPB/NR4A2/C5AR1/SOD2/GAPDH/BNIP3/FAM162A/MCL1/HMOX1/ITGAM/RHOA/GPI/GABRB2/GRN/PTK2B/TYROBP/RB1/AKT1S1/PRNP/GPX1/NRP1	27
GO:0031532	actin cytoskeleton reorganization	17/665	107/18722	2.19216545949872e-07	7.89497270558595e-06	GSN/GMFG/GRB2/PARVB/ANXA1/RALA/FLNA/RHOA/HCLS1/PLEC/ABI3/PTK2B/HAX1/IQGAP2/SIPA1L1/ATP2C1/NRP1	17
GO:0002695	negative regulation of leukocyte activation	23/665	187/18722	2.22538912004338e-07	7.95696685368028e-06	FCGR2B/HLA-DRB1/IL4I1/GPNMB/CD300A/CD74/CEBPB/MERTK/FGL2/HLA-F/LGALS3/TNFAIP3/HMOX1/TNFRSF14/ANXA1/SAMSN1/LAG3/GRN/SPI1/CD86/TYROBP/SMAD7/PRNP	23
GO:0060326	cell chemotaxis	31/665	310/18722	2.2681379937298e-07	8.0518898777408e-06	CXCR4/VEGFA/GPR183/DUSP1/CD74/ADAM8/JAML/ALOX5/CXCL8/C5AR1/MIF/CXCL16/LGALS3/TREM1/RIN3/RAC1/DOCK4/ANXA1/PLEC/WNK1/CXCL2/S100A8/SPI1/CXCL3/RAB13/PTK2B/PPBP/CCL13/NR4A1/CXCL12/NRP1	31
GO:0031349	positive regulation of defense response	29/665	278/18722	2.28460464992058e-07	8.05282631922359e-06	NUPR1/TREM2/ADAM8/NFKBIA/PLSCR1/CLEC7A/CEBPB/NMI/LILRA5/HLA-F/CADM1/IRF7/PYCARD/ALOX5AP/PARP9/IFI35/LAG3/NFKBIZ/EGFR/AKIRIN2/LRRK2/GRN/S100A8/SPI1/HLA-E/TYROBP/TLR2/CD81/RIPK2	29
GO:0006979	response to oxidative stress	39/665	446/18722	2.30320700178757e-07	8.06122450625649e-06	LDHA/TREM2/PAGE4/APOE/CAPN2/DUSP1/TXNIP/JUN/STAT1/BTG1/ALOX5/KLF4/ERO1A/NR4A2/SOD2/NCF1/CD36/IDH1/BNIP3/TNFAIP3/MCL1/HMOX1/FOS/ANXA1/KLF2/RRM2B/PPP2CB/RHOB/EGFR/RBX1/LRRK2/PLK3/MMP14/TXN/PTK2B/CYP1B1/CPEB2/PRNP/GPX1	39
GO:0042542	response to hydrogen peroxide	20/665	146/18722	2.36605959465497e-07	8.22329803177286e-06	LDHA/CAPN2/DUSP1/TXNIP/JUN/STAT1/KLF4/SOD2/BNIP3/TNFAIP3/HMOX1/ANXA1/KLF2/PPP2CB/RHOB/LRRK2/TXN/PTK2B/CYP1B1/GPX1	20
GO:0001906	cell killing	23/665	188/18722	2.45249715252433e-07	8.46452142225412e-06	FCGR2B/HLA-DRB1/HLA-A/HLA-DRA/B2M/LYZ/CTSH/HLA-B/CLEC7A/HLA-F/CADM1/HAMP/MYD88/GAPDH/TREM1/ITGAM/LAG3/IL7R/KIF5B/SPI1/HLA-E/CCL13/TYROBP	23
GO:0002832	negative regulation of response to biotic stimulus	17/665	108/18722	2.51712246774627e-07	8.62765425151654e-06	ISG15/IL4I1/HLA-A/OAS1/OAS3/HLA-B/FGL2/NMI/CARD16/SERPING1/AHR/HLA-F/TNFAIP3/TRIB1/USP18/GRN/HLA-E	17
GO:0051701	biological process involved in interaction with host	24/665	203/18722	2.56701227314469e-07	8.72347426890441e-06	IFIT1/CXCR4/HLA-DRB1/LGALS1/IFITM1/CD74/CXCL8/PLSCR1/TRIM22/IFITM3/IFITM2/GSN/LY6E/ANPEP/TNFRSF14/EGFR/KPNA3/CD86/SELPLG/TFRC/SCARB2/PHB/CD81/NRP1	24
GO:0002704	negative regulation of leukocyte mediated immunity	13/665	63/18722	2.5977347923498e-07	8.72347426890441e-06	FCGR2B/IL4I1/HLA-A/CD300A/HLA-B/AHR/HLA-F/BST2/HMOX1/IL7R/SPI1/HLA-E/SMAD7	13
GO:0031343	positive regulation of cell killing	13/665	63/18722	2.5977347923498e-07	8.72347426890441e-06	HLA-DRB1/HLA-A/HLA-DRA/B2M/HLA-B/CLEC7A/HLA-F/CADM1/ITGAM/LAG3/SPI1/HLA-E/TYROBP	13
GO:0002705	positive regulation of leukocyte mediated immunity	19/665	134/18722	2.73232463174365e-07	9.11386135554759e-06	HLA-DRB1/HLA-A/HLA-DRA/TREM2/B2M/RSAD2/HLA-B/CLEC7A/HLA-F/CADM1/ITGAM/LAG3/PTAFR/SPI1/HLA-E/TYROBP/TFRC/NLRP3/CD81	19
GO:0002709	regulation of T cell mediated immunity	15/665	85/18722	2.76591246669991e-07	9.16438997299905e-06	FCGR2B/HLA-DRB1/IL4I1/HLA-A/HLA-DRA/B2M/RSAD2/HLA-B/AHR/HLA-F/IL7R/HLA-E/NLRP3/CD81/SMAD7	15
GO:0002456	T cell mediated immunity	17/665	109/18722	2.88531376712997e-07	9.49669498187813e-06	FCGR2B/HLA-DRB1/IL4I1/HLA-A/HLA-DRA/B2M/CTSH/RSAD2/MYO1G/HLA-B/AHR/HLA-F/IL7R/HLA-E/NLRP3/CD81/SMAD7	17
GO:0030888	regulation of B cell proliferation	13/665	64/18722	3.15515212834392e-07	1.03165171564929e-05	FCGR2B/GPR183/CD300A/CD74/TNFSF13B/MIF/AHR/IRS2/CDKN1A/TYROBP/TFRC/EPHB2/CD81	13
GO:0035455	response to interferon-alpha	8/665	21/18722	3.28090642936363e-07	1.06575849372139e-05	IFIT3/IFIT2/MX2/IFITM1/EIF2AK2/IFITM3/IFITM2/BST2	8
GO:0006959	humoral immune response	31/665	317/18722	3.7150144579215e-07	1.19893648414739e-05	FCGR2B/SLC11A1/HLA-DRB1/HLA-DQB1/HLA-A/TREM2/GPR183/RNASE6/LYZ/ALOX5/CXCL8/SERPING1/CFD/ANG/C1QB/GAPDH/TREM1/C1QC/PSMB10/GPI/CXCL2/CD83/CXCL3/HLA-E/PPBP/CCL13/EBI3/PHB/CD81/RPL39/C1QA	31
GO:0002700	regulation of production of molecular mediator of immune response	21/665	164/18722	3.78006274781074e-07	1.21205882945932e-05	FCGR2B/HLA-A/B2M/CD74/RSAD2/CLEC7A/HLA-F/CD36/BST2/HMOX1/TNFRSF14/GPI/IL27RA/CD86/HLA-E/TFRC/EPHB2/PHB/NLRP3/CD81/SMAD7	21
GO:0006165	nucleoside diphosphate phosphorylation	16/665	99/18722	3.9069724015851e-07	1.22753657677195e-05	NUPR1/LDHA/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/TPI1/CMPK1/GAPDH/ENO1/GPI/ENO2/PGAM1/GALK1	16
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	16/665	99/18722	3.9069724015851e-07	1.22753657677195e-05	NUPR1/DDIT4/CD74/CRIP1/RPS27L/MIF/CD44/SKIL/PYCARD/SHISA5/MCL1/HMOX1/CDKN1A/ZNF385A/CXCL12/BCL2A1	16
GO:0032102	negative regulation of response to external stimulus	37/665	420/18722	3.92551085462825e-07	1.22753657677195e-05	FCGR2B/ISG15/HLA-DRB1/HLA-A/TREM2/CD9/APOE/DUSP1/OAS1/ALOX5/OAS3/KLF4/HLA-B/ACP5/FGL2/NMI/CARD16/SERPING1/MIF/HLA-F/ZFP36/HAMP/RIN3/TNFAIP3/PTEN/SOCS3/TRIB1/USP18/GRN/PLAU/HLA-E/ANXA2/SIGLEC10/RB1/NLRP3/GPX1/NRP1	37
GO:0001909	leukocyte mediated cytotoxicity	18/665	124/18722	3.9271290886668e-07	1.22753657677195e-05	FCGR2B/HLA-DRB1/HLA-A/HLA-DRA/B2M/CTSH/HLA-B/HLA-F/CADM1/MYD88/TREM1/ITGAM/LAG3/IL7R/KIF5B/SPI1/HLA-E/TYROBP	18
GO:0002285	lymphocyte activation involved in immune response	23/665	194/18722	4.32750742916475e-07	1.3442319951843e-05	FCGR2B/SLC11A1/HLA-DRB1/HLA-DRA/LGALS1/GPR183/CD74/FGL2/HLA-F/LGALS3/ANXA1/IRF8/NFKBIZ/IL27RA/SPI1/CD86/PTK2B/TFRC/HLA-DMB/NLRP3/CD81/SMAD7/RIPK2	23
GO:0045637	regulation of myeloid cell differentiation	24/665	210/18722	4.81656529323906e-07	1.48685276443467e-05	ISG15/HLA-DRB1/TREM2/B2M/CD74/JUN/NFKBIA/STAT1/EVI2B/CEBPB/ZFP36/KLF10/IRF7/MAFB/C1QC/RASSF2/FOS/HCLS1/TRIB1/SPI1/PTK2B/TYROBP/RB1/HAX1	24
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	12/665	56/18722	4.86622114463467e-07	1.49290858573051e-05	HLA-DRB1/HLA-A/HLA-DRA/B2M/HLA-B/HLA-F/CADM1/ITGAM/LAG3/SPI1/HLA-E/TYROBP	12
GO:0022408	negative regulation of cell-cell adhesion	23/665	196/18722	5.20021542136182e-07	1.58558715608394e-05	FCGR2B/HLA-DRB1/IL4I1/VEGFA/CD9/GPNMB/CD300A/CD74/KLF4/FXYD5/CEBPB/FGL2/MYADM/LGALS3/TNFRSF14/ANXA1/LAG3/WNK1/SPI1/CD86/CXCL12/SMAD7/PRNP	23
GO:0007568	aging	32/665	339/18722	5.32876529941305e-07	1.61487582549286e-05	JUND/B2M/LIMS1/JUN/TIMP1/ERO1A/ADM/SOD2/SERPING1/MIF/TSPO/HAMP/NAMPT/CISD2/GRB2/CITED2/PTEN/FOS/LITAF/LMNA/YBX1/LRRK2/MAP3K3/SPI1/CDKN1A/CACYBP/ABI3/KMO/BCL2A1/CD68/PRNP/C1QA	32
GO:0046635	positive regulation of alpha-beta T cell activation	13/665	67/18722	5.52510651877576e-07	1.66099470115607e-05	HLA-DRB1/HLA-A/HLA-DRA/ANXA1/RHOA/NFKBIZ/CD83/CD86/HLA-E/EBI3/NLRP3/CD81/RIPK2	13
GO:0042176	regulation of protein catabolic process	35/665	391/18722	5.57167039188559e-07	1.66099470115607e-05	NUPR1/TREM2/APOE/ADAM8/DAB2/TIMP1/SUMO2/PSME2/HAMP/MSN/N4BP1/GABARAPL2/TNFAIP3/SMURF2/PTEN/FLNA/TRIB1/EGFR/RBX1/TNFSF12/LRRK2/SDCBP/PSMC6/PLK3/CTSA/PTK2B/ANXA2/OAZ1/PHB/CAMLG/FBXL5/TIPARP/CD81/SMAD7/GPX1	35
GO:0031348	negative regulation of defense response	27/665	258/18722	5.58120955921658e-07	1.66099470115607e-05	FCGR2B/ISG15/HLA-DRB1/HLA-A/TREM2/APOE/OAS1/ALOX5/OAS3/KLF4/HLA-B/ACP5/FGL2/NMI/SERPING1/HLA-F/ZFP36/HAMP/TNFAIP3/SOCS3/USP18/GRN/HLA-E/SIGLEC10/RB1/NLRP3/GPX1	27
GO:0046031	ADP metabolic process	15/665	90/18722	5.97566314415622e-07	1.76780034681288e-05	NUPR1/LDHA/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/TPI1/GAPDH/ENO1/GPI/ENO2/PGAM1/GALK1	15
GO:0001933	negative regulation of protein phosphorylation	32/665	342/18722	6.47757886376946e-07	1.90494479011445e-05	APOE/DDIT4/CD300A/DUSP1/CALM1/SH3BP5/MYADM/ERRFI1/GNAQ/TERF2IP/UBE2B/PYCARD/TNFAIP3/RASSF2/PTEN/SOCS3/RGS2/SAMSN1/TRIB1/PLEC/AIDA/LRRK2/CALM3/CDKN1A/RB1/PIK3CB/EPHB2/AKT1S1/CDKN1C/SMAD7/PRNP/DUSP6	32
GO:0009135	purine nucleoside diphosphate metabolic process	16/665	103/18722	6.80206400547055e-07	1.97697415831512e-05	NUPR1/LDHA/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/TPI1/GAPDH/ENO1/GPI/ENO2/PGAM1/GUK1/GALK1	16
GO:0009179	purine ribonucleoside diphosphate metabolic process	16/665	103/18722	6.80206400547055e-07	1.97697415831512e-05	NUPR1/LDHA/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/TPI1/GAPDH/ENO1/GPI/ENO2/PGAM1/GUK1/GALK1	16
GO:0002763	positive regulation of myeloid leukocyte differentiation	12/665	58/18722	7.28279207449881e-07	2.09222408151787e-05	HLA-DRB1/TREM2/CD74/JUN/EVI2B/KLF10/FOS/HCLS1/TRIB1/TYROBP/RB1/HAX1	12
GO:0032481	positive regulation of type I interferon production	12/665	58/18722	7.28279207449881e-07	2.09222408151787e-05	ISG15/OAS2/STAT1/OAS1/OAS3/IFIH1/MYD88/GAPDH/IRF7/TLR2/SETD2/RIPK2	12
GO:0051250	negative regulation of lymphocyte activation	20/665	157/18722	7.75761526962498e-07	2.19869627596503e-05	FCGR2B/HLA-DRB1/IL4I1/GPNMB/CD300A/CD74/CEBPB/MERTK/FGL2/HLA-F/LGALS3/TNFAIP3/TNFRSF14/ANXA1/SAMSN1/LAG3/CD86/TYROBP/SMAD7/PRNP	20
GO:0046634	regulation of alpha-beta T cell activation	16/665	104/18722	7.77830207796763e-07	2.19869627596503e-05	HLA-DRB1/HLA-A/HLA-DRA/CD300A/TNFRSF14/ANXA1/RHOA/NFKBIZ/CD83/CD86/HLA-E/EBI3/NLRP3/CD81/SMAD7/RIPK2	16
GO:0052548	regulation of endopeptidase activity	37/665	432/18722	7.80405006434617e-07	2.19869627596503e-05	VEGFA/PSMB9/CTSH/TIMP1/EGLN3/KLF4/CLEC7A/IFI6/CARD16/PSME2/SERPING1/RPS27L/CD44/BST2/PSMB8/GSN/GAPDH/PYCARD/CSTB/FAM162A/RHOA/GPI/LAMTOR5/AKIRIN2/CTSD/CYCS/PLAUR/S100A8/APH1A/ANXA2/GRAMD4/NR4A1/SERPINB1/NLRP3/RIPK2/PRNP/GPX1	37
GO:0002764	immune response-regulating signaling pathway	39/665	468/18722	7.83036701903039e-07	2.19869627596503e-05	FCGR2B/HLA-DRB1/HLA-DQB1/FPR3/HLA-A/TREM2/HLA-DPB1/CD300A/CTSH/NFKBIA/OAS1/OAS3/IFIH1/RSAD2/MYO1G/PLSCR1/CLEC7A/NMI/C5AR1/CD36/RAP1A/MYD88/LGALS3/IRF7/TNFAIP3/GBP1/IFI35/NFKBIZ/DDX60/WNK1/OASL/TYROBP/GRAMD4/TLR2/PHB/WDFY1/CD81/RIPK2/PRNP	39
GO:0009612	response to mechanical stimulus	24/665	216/18722	8.06550192727342e-07	2.25199688643533e-05	CXCR4/JUND/TXNIP/JUN/NFKBIA/STAT1/SLC1A3/GSN/FOSB/SLC38A2/MYD88/BNIP3/CITED2/RAC1/FOS/RHOA/GPI/EGFR/PLEC/MAP3K2/MMP14/PTK2B/CXCL12/XPC	24
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	27/665	264/18722	8.78382588517597e-07	2.43886115359355e-05	TREM2/VEGFA/CD300A/CD74/SH3BP5/CLEC7A/ERRFI1/MIF/LILRA5/CD44/NCF1/CD36/ABI1/SOCS3/TNFRSF14/PARP9/HCLS1/SAMSN1/EGFR/PTK2B/ARL2BP/IGF2/HAX1/CD81/RIPK2/PRNP/NRP1	27
GO:2000106	regulation of leukocyte apoptotic process	14/665	81/18722	8.96684113374987e-07	2.47584446859649e-05	TSC22D3/CD74/ADAM8/MERTK/IRS2/LGALS3/IRF7/PTEN/ANXA1/HCLS1/IL7R/DOCK8/PIK3CB/CXCL12	14
GO:0051099	positive regulation of binding	21/665	173/18722	9.25458638854225e-07	2.5411764834837e-05	B2M/APOE/CALM1/KLF4/S100A10/CLIC2/MAPRE1/DTX3L/PARP9/PPP2CB/LAMTOR5/EPB41/LRRK2/PLAUR/CALM3/EDF1/TXN/ANXA2/RB1/RIPK2/NRP1	21
GO:0001910	regulation of leukocyte mediated cytotoxicity	14/665	82/18722	1.04646294688362e-06	2.85764881648988e-05	FCGR2B/HLA-DRB1/HLA-A/HLA-DRA/B2M/HLA-B/HLA-F/CADM1/ITGAM/LAG3/IL7R/SPI1/HLA-E/TYROBP	14
GO:2000116	regulation of cysteine-type endopeptidase activity	25/665	235/18722	1.07770624066979e-06	2.92688525471523e-05	VEGFA/PSMB9/CTSH/EGLN3/KLF4/CLEC7A/IFI6/CARD16/RPS27L/CD44/GSN/PYCARD/FAM162A/RHOA/GPI/LAMTOR5/CTSD/CYCS/PLAUR/S100A8/GRAMD4/NR4A1/NLRP3/RIPK2/GPX1	25
GO:0035456	response to interferon-beta	9/665	32/18722	1.14863810689532e-06	3.08735400931425e-05	XAF1/IFITM1/CAPN2/STAT1/OAS1/PLSCR1/IFITM3/IFITM2/BST2	9
GO:0042113	B cell activation	31/665	334/18722	1.15044359119757e-06	3.08735400931425e-05	FCGR2B/IL4I1/LGALS1/GPR183/CD300A/CD74/ZFP36L2/TNFSF13B/MIF/AHR/KLF6/BST2/IRS2/IRF2BP2/TNFAIP3/IRF8/SAMSN1/IL7R/IL27RA/MMP14/TPD52/SPI1/CDKN1A/CD86/PTK2B/TYROBP/TFRC/EPHB2/PHB/CMTM7/CD81	31
GO:0072659	protein localization to plasma membrane	28/665	284/18722	1.15542826103109e-06	3.08735400931425e-05	TREM2/DAB2/S100A10/MYADM/RAB8A/VAMP5/RAP1A/LGALS3/FCHO2/GBP1/GOLGA7/FLNA/EGFR/KRT18/MYL12A/MMP14/KIF5B/STX3/RAB13/ABI3/SQSTM1/ANXA2/EPHB2/RAB31/TMEM59/CD81/ATP2C1/PRNP	28
GO:0002761	regulation of myeloid leukocyte differentiation	17/665	120/18722	1.1676378225125e-06	3.103294105822e-05	HLA-DRB1/TREM2/CD74/JUN/EVI2B/CEBPB/KLF10/IRF7/MAFB/C1QC/RASSF2/FOS/HCLS1/TRIB1/TYROBP/RB1/HAX1	17
GO:0032479	regulation of type I interferon production	15/665	95/18722	1.22208413497374e-06	3.21362865122726e-05	ISG15/OAS2/STAT1/OAS1/OAS3/IFIH1/NMI/MYD88/GAPDH/IRF7/PYCARD/IRF8/TLR2/SETD2/RIPK2	15
GO:0032606	type I interferon production	15/665	95/18722	1.22208413497374e-06	3.21362865122726e-05	ISG15/OAS2/STAT1/OAS1/OAS3/IFIH1/NMI/MYD88/GAPDH/IRF7/PYCARD/IRF8/TLR2/SETD2/RIPK2	15
GO:0016064	immunoglobulin mediated immune response	23/665	207/18722	1.36327812723076e-06	3.56604857491415e-05	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/TREM2/HLA-DPB1/HLA-DPA1/B2M/CD74/HLA-DOA/SERPING1/HLA-DMA/C1QB/MYD88/IRF7/C1QC/IL27RA/HLA-E/TFRC/HLA-DMB/CD81/C1QA	23
GO:0009895	negative regulation of catabolic process	30/665	320/18722	1.38920327621501e-06	3.61483784439195e-05	NUPR1/SLC11A1/TREM2/DDIT4/APOC1/TIMP1/FBP1/YBX3/TSPO/ZFP36/NAMPT/MYD88/N4BP1/GABARAPL2/MCL1/HMOX1/FLNA/YBX1/EGFR/LRRK2/SDCBP/TAB2/HNRNPA0/CTSA/RNF5/ANXA2/TOB1/PHB/CAMLG/ELAVL1	30
GO:0002687	positive regulation of leukocyte migration	18/665	135/18722	1.40769486643801e-06	3.64387681572756e-05	TREM2/VEGFA/CD74/ADAM8/CXCL8/C5AR1/LGALS3/PYCARD/RAC1/TNFRSF14/RHOA/PTAFR/WNK1/MMP14/SPI1/PTK2B/DOCK8/CXCL12	18
GO:1902563	regulation of neutrophil activation	6/665	12/18722	1.51106042956233e-06	3.89117633933925e-05	FCGR2B/CD300A/ITGAM/PTAFR/GRN/SPI1	6
GO:2001234	negative regulation of apoptotic signaling pathway	24/665	224/18722	1.55335289267129e-06	3.96738437527189e-05	CD74/IFI6/YBX3/NR4A2/SOD2/MIF/CD44/LGALS3/ENO1/PEA15/TNFAIP3/MCL1/HMOX1/RRM2B/LMNA/LRRK2/PLAUR/RB1/ZNF385A/GRINA/IVNS1ABP/CXCL12/GPX1/NRP1	24
GO:2001242	regulation of intrinsic apoptotic signaling pathway	20/665	164/18722	1.55661962410064e-06	3.96738437527189e-05	NUPR1/TREM2/CD74/YBX3/SOD2/MIF/CD44/SKIL/PYCARD/ENO1/MCL1/RRM2B/LRRK2/PLAUR/S100A8/ZNF385A/GRINA/IVNS1ABP/CXCL12/GPX1	20
GO:0048872	homeostasis of number of cells	27/665	272/18722	1.57005152363713e-06	3.98120207779414e-05	ISG15/TSC22D3/VEGFA/GPR183/B2M/CD74/STAT1/TNFSF13B/MERTK/SKIL/ZFP36/HAMP/MAFB/TNFAIP3/CITED2/RASSF2/HMOX1/ANXA1/KLF2/HCLS1/GPI/IL7R/SPI1/SOS2/RB1/PIK3CB/CAMLG	27
GO:1901216	positive regulation of neuron death	15/665	97/18722	1.60444668934876e-06	4.04470373587239e-05	FCGR2B/NUPR1/DDIT4/CAPN2/JUN/MCL1/FOS/ITGAM/RHOA/EGR1/GRN/TYROBP/KMO/PRNP/C1QA	15
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	23/665	209/18722	1.61137090483447e-06	4.04470373587239e-05	VEGFA/CTSH/EGLN3/KLF4/CLEC7A/IFI6/CARD16/RPS27L/CD44/GSN/PYCARD/FAM162A/RHOA/GPI/LAMTOR5/CTSD/CYCS/PLAUR/S100A8/GRAMD4/NR4A1/NLRP3/GPX1	23
GO:0032635	interleukin-6 production	20/665	165/18722	1.71353680770293e-06	4.25813896714178e-05	TREM2/CAPN2/CD74/IFIH1/HLA-B/IL1RAP/CLEC7A/CEBPB/LILRA5/CD36/MYD88/PYCARD/TNFAIP3/KLF2/AKIRIN2/PTAFR/IL27RA/TYROBP/TLR2/RIPK2	20
GO:0032675	regulation of interleukin-6 production	20/665	165/18722	1.71353680770293e-06	4.25813896714178e-05	TREM2/CAPN2/CD74/IFIH1/HLA-B/IL1RAP/CLEC7A/CEBPB/LILRA5/CD36/MYD88/PYCARD/TNFAIP3/KLF2/AKIRIN2/PTAFR/IL27RA/TYROBP/TLR2/RIPK2	20
GO:0019724	B cell mediated immunity	23/665	210/18722	1.75031973176893e-06	4.32790500840377e-05	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/TREM2/HLA-DPB1/HLA-DPA1/B2M/CD74/HLA-DOA/SERPING1/HLA-DMA/C1QB/MYD88/IRF7/C1QC/IL27RA/HLA-E/TFRC/HLA-DMB/CD81/C1QA	23
GO:0002367	cytokine production involved in immune response	15/665	98/18722	1.833226715235e-06	4.48824471660982e-05	HLA-A/B2M/CD74/RSAD2/CLEC7A/HLA-F/CD36/BST2/TREM1/HMOX1/TNFRSF14/HLA-E/NLRP3/CD81/SMAD7	15
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	15/665	98/18722	1.833226715235e-06	4.48824471660982e-05	CD74/YBX3/SOD2/MIF/CD44/ENO1/MCL1/RRM2B/LRRK2/PLAUR/ZNF385A/GRINA/IVNS1ABP/CXCL12/GPX1	15
GO:0009132	nucleoside diphosphate metabolic process	17/665	124/18722	1.8601400006637e-06	4.53181166828363e-05	NUPR1/LDHA/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/TPI1/CMPK1/GAPDH/ENO1/GPI/ENO2/PGAM1/GUK1/GALK1	17
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	10/665	43/18722	1.9825790218228e-06	4.80654523827284e-05	NUPR1/DDIT4/CD74/RPS27L/MIF/CD44/PYCARD/SHISA5/CDKN1A/ZNF385A	10
GO:0031341	regulation of cell killing	15/665	99/18722	2.09082126435579e-06	5.04436004070305e-05	FCGR2B/HLA-DRB1/HLA-A/HLA-DRA/B2M/HLA-B/CLEC7A/HLA-F/CADM1/ITGAM/LAG3/IL7R/SPI1/HLA-E/TYROBP	15
GO:1901222	regulation of NIK/NF-kappaB signaling	16/665	112/18722	2.14332184281649e-06	5.13419584204806e-05	TREM2/LIMS1/NFKBIA/EIF2AK2/NMI/TERF2IP/RASSF2/RHOA/LITAF/IFI35/EGFR/SPI1/CD86/TLR2/PHB/NLRP3	16
GO:0006898	receptor-mediated endocytosis	25/665	244/18722	2.14871777695372e-06	5.13419584204806e-05	FCGR2B/VEGFA/B2M/CD9/APOE/APOC1/DAB2/CXCL8/ADM/CD36/CXCL16/RIN3/MSR1/GRB2/FCHO2/RAC1/ITGAM/SDCBP/CAP1/ANXA2/TFRC/PIK3CB/SCARB2/RAB31/CD81	25
GO:0046034	ATP metabolic process	27/665	277/18722	2.2275633343703e-06	5.29712429273702e-05	NUPR1/LDHA/TREM2/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/TPI1/TSPO/SDHD/GAPDH/ENO1/OLA1/DNAJC15/RHOA/GPI/COA6/ENO2/PGAM1/CYCS/ATP6V1B2/GUK1/COX5B/GALK1/FAM20C	27
GO:0002706	regulation of lymphocyte mediated immunity	20/665	168/18722	2.27450438495499e-06	5.38299371106015e-05	FCGR2B/HLA-DRB1/IL4I1/HLA-A/HLA-DRA/TREM2/B2M/RSAD2/HLA-B/AHR/HLA-F/CADM1/LAG3/IL7R/IL27RA/HLA-E/TFRC/NLRP3/CD81/SMAD7	20
GO:0016052	carbohydrate catabolic process	19/665	154/18722	2.37393692770274e-06	5.59169029890172e-05	NUPR1/LDHA/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/TPI1/GAPDH/PPP1CB/ENO1/PPP1R3B/GPI/ENO2/PGAM1/HEXB/SCARB2/GALK1	19
GO:0070371	ERK1 and ERK2 cascade	30/665	330/18722	2.61538321285546e-06	6.13134649428852e-05	HLA-DRB1/TREM2/GPR183/GPNMB/APOE/CTSH/DUSP1/CD74/ZFP36L2/KLF4/ATF3/ERRFI1/C5AR1/MIF/CD44/CD36/RAP1A/PYCARD/PTEN/GBP1/EGFR/GLIPR2/PTK2B/CCL13/EPHB2/FN1/PHB/RIPK2/DUSP6/NRP1	30
GO:1903038	negative regulation of leukocyte cell-cell adhesion	18/665	141/18722	2.66203412786236e-06	6.21141296501217e-05	FCGR2B/HLA-DRB1/IL4I1/GPNMB/CD300A/CD74/KLF4/CEBPB/FGL2/LGALS3/TNFRSF14/ANXA1/LAG3/WNK1/CD86/CXCL12/SMAD7/PRNP	18
GO:0042102	positive regulation of T cell proliferation	15/665	101/18722	2.7053057245868e-06	6.28288292111981e-05	HLA-A/HLA-DPB1/HLA-DPA1/TNFSF13B/PYCARD/ANXA1/IL27RA/CD86/HLA-E/IGF2/TFRC/EBI3/HLA-DMB/CD81/RIPK2	15
GO:0002286	T cell activation involved in immune response	16/665	114/18722	2.71951568625949e-06	6.28650835381846e-05	FCGR2B/SLC11A1/HLA-DRB1/HLA-DRA/GPR183/CD74/FGL2/LGALS3/ANXA1/NFKBIZ/CD86/HLA-DMB/NLRP3/CD81/SMAD7/RIPK2	16
GO:0046631	alpha-beta T cell activation	19/665	156/18722	2.88344253460435e-06	6.63458768378871e-05	HLA-DRB1/HLA-A/HLA-DRA/GPR183/CD300A/RSAD2/TNFRSF14/ANXA1/RHOA/NFKBIZ/CLEC4A/CD83/CD86/HLA-E/EBI3/NLRP3/CD81/SMAD7/RIPK2	19
GO:1990778	protein localization to cell periphery	30/665	333/18722	3.14322499048564e-06	7.19899917175744e-05	TREM2/DAB2/S100A10/MYADM/RAB8A/VAMP5/RAP1A/LGALS3/FCHO2/GBP1/GOLGA7/FLNA/EGFR/EPB41/KRT18/LIN7C/MYL12A/MMP14/KIF5B/STX3/RAB13/ABI3/SQSTM1/ANXA2/EPHB2/RAB31/TMEM59/CD81/ATP2C1/PRNP	30
GO:0051090	regulation of DNA-binding transcription factor activity	36/665	440/18722	3.17316975032279e-06	7.23424479775424e-05	NUPR1/VEGFA/ADAM8/NFKBIA/EIF2AK2/SGK1/ADORA3/KLF4/IL1RAP/TRIM22/CLEC7A/CARD16/TMIGD3/CD36/BHLHE40/TERF2IP/MYD88/PYCARD/TNFAIP3/PTEN/HMOX1/FLNA/HCLS1/LAMTOR5/EGLN1/TRIB1/S100A8/SPI1/TFRC/RB1/CYP1B1/TLR2/NLRP3/SMAD7/RIPK2/PRNP	36
GO:0002221	pattern recognition receptor signaling pathway	20/665	172/18722	3.28135080619459e-06	7.44671849624981e-05	TREM2/CD300A/NFKBIA/OAS1/OAS3/IFIH1/RSAD2/NMI/CD36/MYD88/IRF7/TNFAIP3/IFI35/DDX60/OASL/GRAMD4/TLR2/PHB/WDFY1/RIPK2	20
GO:0042119	neutrophil activation	9/665	36/18722	3.3945650614749e-06	7.66863107069556e-05	FCGR2B/CD300A/CXCL8/MYD88/ITGAM/PTAFR/GRN/SPI1/TYROBP	9
GO:0060191	regulation of lipase activity	14/665	91/18722	3.78729113897245e-06	8.51712079669369e-05	APOC1/C5AR1/GNAQ/ANG/ANXA1/RHOA/RGS2/EGFR/RHOC/PTAFR/CD86/PHB/ANGPTL4/ABHD5	14
GO:0002702	positive regulation of production of molecular mediator of immune response	16/665	117/18722	3.84607486978899e-06	8.57174533760148e-05	HLA-A/B2M/CD74/RSAD2/CLEC7A/HLA-F/CD36/TNFRSF14/GPI/CD86/HLA-E/TFRC/EPHB2/PHB/NLRP3/CD81	16
GO:0072676	lymphocyte migration	16/665	117/18722	3.84607486978899e-06	8.57174533760148e-05	GPR183/ADAM8/MYO1G/ECM1/CXCL16/MSN/PYCARD/TNFRSF14/RHOA/PLEC/WNK1/IL27RA/PTK2B/DOCK8/CCL13/CXCL12	16
GO:0045619	regulation of lymphocyte differentiation	20/665	174/18722	3.92323555796638e-06	8.70467889423791e-05	HLA-DRB1/IL4I1/HLA-DRA/CD74/ADAM8/ZFP36L2/FGL2/HLA-DOA/ANXA1/RHOA/LAG3/NFKBIZ/IL7R/CD83/MMP14/SOS2/CD86/NLRP3/SMAD7/RIPK2	20
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	8/665	28/18722	4.01926809395673e-06	8.87811663420664e-05	HLA-A/B2M/HLA-B/HLA-C/HLA-F/CLEC4A/HLA-E/IFI30	8
GO:0071346	cellular response to interferon-gamma	16/665	118/18722	4.30543222468672e-06	9.46814077729778e-05	VIM/HLA-DPA1/STAT1/NMI/GAPDH/RAB20/GBP1/PARP9/IRF8/IFNGR2/GBP4/KIF5B/CD58/GBP3/CCL13/TLR2	16
GO:0045580	regulation of T cell differentiation	18/665	146/18722	4.40011448341198e-06	9.63373082932051e-05	HLA-DRB1/IL4I1/HLA-DRA/CD74/ADAM8/FGL2/HLA-DOA/ANXA1/RHOA/LAG3/NFKBIZ/IL7R/CD83/SOS2/CD86/NLRP3/SMAD7/RIPK2	18
GO:0001774	microglial cell activation	10/665	47/18722	4.70988528673379e-06	0.000102667236294153	TREM2/C5AR1/NAMPT/ITGAM/IFNGR2/LRRK2/GRN/TYROBP/TLR2/C1QA	10
GO:1903362	regulation of cellular protein catabolic process	25/665	255/18722	4.74651780097225e-06	0.000103013945287476	NUPR1/TREM2/APOE/DAB2/SUMO2/PSME2/HAMP/MSN/N4BP1/GABARAPL2/TNFAIP3/PTEN/TRIB1/RBX1/LRRK2/SDCBP/PSMC6/PLK3/PTK2B/ANXA2/CAMLG/FBXL5/CD81/SMAD7/GPX1	25
GO:0072593	reactive oxygen species metabolic process	24/665	239/18722	4.85231930219726e-06	0.00010485229100835	PAGE4/DDIT4/ALOX5/HK2/ACP5/CLEC7A/IFI6/SOD2/NCF1/HBG1/TSPO/CD36/BNIP3/GRB2/RAC1/ITGAM/RHOA/EGFR/LRRK2/CDKN1A/PTK2B/TYROBP/CYP1B1/GPX1	24
GO:0006090	pyruvate metabolic process	15/665	106/18722	5.00356312215219e-06	0.000107652418688729	NUPR1/LDHA/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/TPI1/GAPDH/ENO1/GPI/ENO2/PGAM1/GALK1	15
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	21/665	193/18722	5.42982503175945e-06	0.000116280505961595	TREM2/VEGFA/CD74/CLEC7A/MIF/LILRA5/CD44/NCF1/CD36/ABI1/TNFRSF14/PARP9/HCLS1/PTK2B/ARL2BP/IGF2/HAX1/CD81/RIPK2/PRNP/NRP1	21
GO:0030217	T cell differentiation	25/665	257/18722	5.45137985695202e-06	0.000116280505961595	HLA-DRB1/IL4I1/HLA-DRA/GPR183/B2M/CD74/ADAM8/ZFP36L2/RSAD2/FGL2/HLA-DOA/MAFB/ANXA1/RHOA/EGR1/LAG3/NFKBIZ/IL7R/CD83/SPI1/SOS2/CD86/NLRP3/SMAD7/RIPK2	25
GO:0030316	osteoclast differentiation	14/665	94/18722	5.60178393452993e-06	0.000118860969018786	TREM2/GPR183/CEBPB/SNX10/KLF10/MAFB/JUNB/RASSF2/FOS/ANXA2/TYROBP/TFRC/OSCAR/CD81	14
GO:0008637	apoptotic mitochondrial changes	15/665	107/18722	5.63165319143164e-06	0.000118860969018786	IFIT2/JUN/HK2/IFI6/SOD2/BNIP3L/BNIP3/PYCARD/FAM162A/PPP2CB/LMNA/BLOC1S2/PLAUR/ATG3/GPX1	15
GO:0051051	negative regulation of transport	37/665	470/18722	5.6441023517975e-06	0.000118860969018786	FCGR2B/APOE/CD300A/APOC1/CD74/CALM1/RSAD2/PLSCR1/HLA-F/CD36/BST2/IRS2/HAMP/CLIC2/RAP1A/LGALS3/RIN3/PEA15/PTEN/HMOX1/RAC1/ANXA1/KCNE1/RGS2/LRRK2/SDCBP/WNK1/CALM3/C4orf3/SPI1/TXN/PTK2B/ATG3/EPHB2/OAZ1/TLR2/MDFIC	37
GO:0051235	maintenance of location	29/665	326/18722	5.85892058429561e-06	0.000122487002444225	PLIN2/SRGN/TREM2/APOE/NFKBIA/HK2/CALM1/ERO1A/FTH1/TSPO/CD36/GSN/CLIC2/MSR1/FTL/FLNA/SOAT1/FBN2/INSIG2/TMSB10/CALM3/S100A8/TXN/PTK2B/ARL2BP/DIAPH1/HEXB/ABHD5/VPS13A	29
GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	12/665	70/18722	5.88583874854886e-06	0.000122487002444225	HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/HLA-DPB1/HLA-DPA1/B2M/HLA-DOA/HLA-DMA/IL27RA/TFRC/HLA-DMB	12
GO:1901654	response to ketone	21/665	194/18722	5.89022003705628e-06	0.000122487002444225	DDIT4/DUSP1/TXNIP/CALM1/KLF4/ERRFI1/CSNK2B/AHR/TSPO/FOSB/MSN/FOS/KLF2/GPI/EGFR/PTAFR/CALM3/CDKN1A/KLF9/EIF4E/TLR2	21
GO:0070372	regulation of ERK1 and ERK2 cascade	28/665	309/18722	5.96942535094139e-06	0.000123616849975745	HLA-DRB1/TREM2/GPR183/GPNMB/APOE/DUSP1/CD74/KLF4/ATF3/ERRFI1/C5AR1/MIF/CD44/CD36/RAP1A/PYCARD/PTEN/GBP1/EGFR/GLIPR2/PTK2B/CCL13/EPHB2/FN1/PHB/RIPK2/DUSP6/NRP1	28
GO:0050764	regulation of phagocytosis	14/665	95/18722	6.3587690850705e-06	0.000131133121795852	FCGR2B/SLC11A1/TREM2/CD300A/PLSCR1/CLEC7A/MERTK/CD36/RAP1A/PYCARD/PTEN/ATG3/TLR2/RAB31	14
GO:0045824	negative regulation of innate immune response	12/665	71/18722	6.85709509695572e-06	0.00014082546542095	ISG15/HLA-A/OAS1/OAS3/HLA-B/NMI/SERPING1/HLA-F/TNFAIP3/USP18/GRN/HLA-E	12
GO:0001914	regulation of T cell mediated cytotoxicity	9/665	39/18722	6.94623860879944e-06	0.000141486909367759	FCGR2B/HLA-DRB1/HLA-A/HLA-DRA/B2M/HLA-B/HLA-F/IL7R/HLA-E	9
GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	9/665	39/18722	6.94623860879944e-06	0.000141486909367759	HLA-DRB1/HLA-DRA/ANXA1/NFKBIZ/CD83/CD86/NLRP3/CD81/RIPK2	9
GO:0001913	T cell mediated cytotoxicity	10/665	49/18722	7.0109707938385e-06	0.000141644409940558	FCGR2B/HLA-DRB1/HLA-A/HLA-DRA/B2M/CTSH/HLA-B/HLA-F/IL7R/HLA-E	10
GO:0052372	modulation by symbiont of entry into host	10/665	49/18722	7.0109707938385e-06	0.000141644409940558	HLA-DRB1/LGALS1/IFITM1/CD74/CXCL8/TRIM22/IFITM3/IFITM2/GSN/LY6E	10
GO:0043523	regulation of neuron apoptotic process	22/665	212/18722	7.06801374171686e-06	0.000142218738041833	NUPR1/TREM2/APOE/ADAM8/JUN/EGLN3/CEBPB/NR4A2/C5AR1/SOD2/MCL1/HMOX1/ITGAM/RHOA/GPI/GABRB2/GRN/PTK2B/TYROBP/AKT1S1/PRNP/NRP1	22
GO:0045766	positive regulation of angiogenesis	20/665	181/18722	7.166416501691e-06	0.000143040522142186	CXCR4/VEGFA/CTSH/BTG1/HK2/CXCL8/KLF4/PKM/ADM/C5AR1/ECM1/HMOX1/RHOB/TNFSF12/GRN/ACVRL1/PTK2B/CYP1B1/ANGPTL4/NRP1	20
GO:1904018	positive regulation of vasculature development	20/665	181/18722	7.166416501691e-06	0.000143040522142186	CXCR4/VEGFA/CTSH/BTG1/HK2/CXCL8/KLF4/PKM/ADM/C5AR1/ECM1/HMOX1/RHOB/TNFSF12/GRN/ACVRL1/PTK2B/CYP1B1/ANGPTL4/NRP1	20
GO:0002718	regulation of cytokine production involved in immune response	14/665	96/18722	7.20511374426646e-06	0.000143237661236017	HLA-A/B2M/CD74/RSAD2/CLEC7A/HLA-F/CD36/BST2/HMOX1/TNFRSF14/HLA-E/NLRP3/CD81/SMAD7	14
GO:0042594	response to starvation	21/665	197/18722	7.49143278443319e-06	0.000148336338400928	PAGE4/JUN/EIF2AK2/GLUL/ADM/ATF3/UPP1/ZFP36/HAMP/SLC38A2/MAP1LC3B/KLF10/GABARAPL2/DNAJC15/EIF4EBP1/WDR45B/LRRK2/RRAGD/CDKN1A/HNRNPA1/WIPI2	21
GO:0031330	negative regulation of cellular catabolic process	25/665	262/18722	7.65065172881931e-06	0.000150887853540603	NUPR1/SLC11A1/TREM2/APOC1/TIMP1/YBX3/TSPO/ZFP36/NAMPT/MYD88/N4BP1/GABARAPL2/MCL1/HMOX1/YBX1/LRRK2/SDCBP/TAB2/HNRNPA0/CTSA/RNF5/ANXA2/TOB1/CAMLG/ELAVL1	25
GO:0032611	interleukin-1 beta production	15/665	110/18722	7.95862958542287e-06	0.000155725941100597	TREM2/ACP5/CLEC7A/ERRFI1/CARD16/LILRA5/CD36/MYD88/PYCARD/TNFAIP3/EGR1/TYROBP/SERPINB1/NLRP3/RIPK2	15
GO:0032651	regulation of interleukin-1 beta production	15/665	110/18722	7.95862958542287e-06	0.000155725941100597	TREM2/ACP5/CLEC7A/ERRFI1/CARD16/LILRA5/CD36/MYD88/PYCARD/TNFAIP3/EGR1/TYROBP/SERPINB1/NLRP3/RIPK2	15
GO:0031099	regeneration	21/665	198/18722	8.10682985226905e-06	0.000158003703395205	CD9/SULF2/KLF4/CEBPB/ADM/C5AR1/CSNK2B/TSPO/HAMP/RAP1A/PTEN/HMOX1/ANXA1/FLNA/PTPN12/EGFR/GRN/CDKN1A/CXCL12/CD81/GPX1	21
GO:0042742	defense response to bacterium	30/665	350/18722	8.48395358136792e-06	0.000164708005075776	ISG15/SLC11A1/OAS2/HLA-A/TREM2/RNASE6/LYZ/OAS1/OAS3/ACP5/CEBPB/C5AR1/CD36/HAMP/ANG/MYD88/TREM1/PYCARD/TNFRSF14/IRF8/IL7R/GBP4/IL27RA/GRN/S100A8/HLA-E/PPBP/TLR2/RIPK2/RPL39	30
GO:0031098	stress-activated protein kinase signaling cascade	24/665	247/18722	8.52809771914779e-06	0.000164920800249667	FCGR2B/TREM2/PAGE4/VEGFA/DUSP1/EIF2AK2/CLEC7A/NCF1/ZFP36/MYD88/PYCARD/RASSF2/RHOA/TRIB1/EGFR/AIDA/LRRK2/SDCBP/MAP3K3/SPI1/PTK2B/MDFIC/PER1/RIPK2	24
GO:0002833	positive regulation of response to biotic stimulus	19/665	168/18722	8.62657538789013e-06	0.00016617860340238	HLA-DRB1/ADAM8/PLSCR1/CLEC7A/NMI/HLA-F/CADM1/IRF7/PYCARD/PARP9/IFI35/LAG3/AKIRIN2/DDX60/GRN/SPI1/OASL/HLA-E/TYROBP	19
GO:2000401	regulation of lymphocyte migration	11/665	61/18722	8.66963751638135e-06	0.000166363314503534	ADAM8/ECM1/MSN/PYCARD/TNFRSF14/RHOA/WNK1/IL27RA/PTK2B/DOCK8/CXCL12	11
GO:0045732	positive regulation of protein catabolic process	23/665	231/18722	8.76678371185464e-06	0.000167580442491991	NUPR1/TREM2/APOE/ADAM8/DAB2/SUMO2/HAMP/MSN/TNFAIP3/SMURF2/PTEN/TRIB1/RBX1/TNFSF12/LRRK2/PSMC6/PLK3/PTK2B/OAZ1/FBXL5/TIPARP/CD81/SMAD7	23
GO:1904375	regulation of protein localization to cell periphery	16/665	125/18722	9.15372005319073e-06	0.000174306469978383	TREM2/DAB2/RAP1A/LGALS3/GBP1/EGFR/EPB41/MMP14/KIF5B/STX3/ABI3/SQSTM1/EPHB2/TMEM59/ATP2C1/PRNP	16
GO:0002828	regulation of type 2 immune response	8/665	31/18722	9.28290729988479e-06	0.000176091791146669	CD74/RSAD2/ECM1/ANXA1/IL27RA/CD86/NLRP3/CD81	8
GO:0008360	regulation of cell shape	18/665	154/18722	9.36339395097519e-06	0.000176943224092573	VEGFA/ALDOA/MSN/RAC1/PARVB/PDPN/ANXA1/RHOA/RHOB/RHOC/EPB41/MYL12A/RND3/PTK2B/DIAPH1/CCL13/FN1/HEXB	18
GO:0009410	response to xenobiotic stimulus	36/665	462/18722	9.45538278620442e-06	0.000178004744119076	CXCR4/LDHA/PLIN2/LGALS1/B2M/TXNIP/JUN/STAT1/FBP1/SLC1A3/S100A10/ACSL1/SOD2/AHR/TSPO/UBE2B/FOSB/RAP1A/PTEN/HMOX1/FOS/ANXA1/RHOA/EGFR/CDKN1A/AGPAT2/PTK2B/VKORC1/GUK1/TFRC/RB1/CYP1B1/PRNP/XPC/GPX1/DUSP6	36
GO:0010506	regulation of autophagy	28/665	317/18722	9.66110921822148e-06	0.00018119136911155	NUPR1/TREM2/TRIM22/BNIP3L/RAB8A/TSPO/PIP4K2A/NAMPT/GAPDH/BNIP3/CISD2/PYCARD/MCL1/HMOX1/ATP6V1G1/LRRK2/TAB2/PLK3/RRAGD/CTSA/CAPNS1/ATP6V1B2/RNF5/PIK3CB/HAX1/TMEM59/RIPK2/PSAP	28
GO:1903364	positive regulation of cellular protein catabolic process	18/665	155/18722	1.02497179098045e-05	0.000191507887262136	NUPR1/TREM2/APOE/DAB2/SUMO2/HAMP/MSN/TNFAIP3/PTEN/TRIB1/RBX1/LRRK2/PSMC6/PLK3/PTK2B/FBXL5/CD81/SMAD7	18
GO:0032602	chemokine production	14/665	99/18722	1.03739139959627e-05	0.000192381912537069	TREM2/CD74/EIF2AK2/OAS1/OAS3/KLF4/CLEC7A/MYD88/TREM1/PYCARD/HMOX1/EGR1/TLR2/RIPK2	14
GO:0042100	B cell proliferation	14/665	99/18722	1.03739139959627e-05	0.000192381912537069	FCGR2B/GPR183/CD300A/CD74/TNFSF13B/MIF/AHR/IRS2/IL7R/CDKN1A/TYROBP/TFRC/EPHB2/CD81	14
GO:0051348	negative regulation of transferase activity	25/665	268/18722	1.13401476078724e-05	0.000209518712309018	APOE/CD300A/DUSP1/SH3BP5/ERRFI1/GNAQ/ZFP36/IRS2/PIP4K2A/PYCARD/TNFAIP3/PTEN/DTX3L/RGS2/TRIB1/PLEC/AIDA/WNK1/CDKN1A/RB1/PIK3CB/EPHB2/AKT1S1/CDKN1C/SMAD7	25
GO:0033674	positive regulation of kinase activity	36/665	467/18722	1.19664801706058e-05	0.000219161109963773	SLC11A1/HLA-DRB1/TREM2/VEGFA/CD300A/CD74/ADAM8/CALM1/MERTK/ACSL1/LILRA5/NCF1/ANG/RAP1A/ABI1/RASSF2/CCNY/RHOA/EGR1/DAZAP2/EGFR/LRRK2/WNK1/TAB2/CALM3/CDKN1A/TXN/CAMK1/CD86/PTK2B/IGF2/MMD/EPHB2/PHB/CD81/PRNP	36
GO:0050729	positive regulation of inflammatory response	17/665	142/18722	1.19826542933877e-05	0.000219161109963773	NUPR1/TREM2/ADAM8/NFKBIA/CEBPB/NMI/LILRA5/ALOX5AP/IFI35/NFKBIZ/EGFR/LRRK2/GRN/S100A8/HLA-E/TLR2/CD81	17
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	8/665	32/18722	1.19943303642145e-05	0.000219161109963773	HLA-DRB1/HLA-DRA/ANXA1/NFKBIZ/CD83/CD86/NLRP3/RIPK2	8
GO:2000377	regulation of reactive oxygen species metabolic process	18/665	157/18722	1.22512868461875e-05	0.000223036247712644	PAGE4/ALOX5/HK2/ACP5/CLEC7A/SOD2/TSPO/CD36/BNIP3/GRB2/RAC1/ITGAM/RHOA/EGFR/CDKN1A/PTK2B/TYROBP/CYP1B1	18
GO:0032612	interleukin-1 production	16/665	128/18722	1.24236325764997e-05	0.000224528923291649	TREM2/ACP5/CLEC7A/ERRFI1/CARD16/LILRA5/CD36/MYD88/PYCARD/TNFAIP3/ANXA1/EGR1/TYROBP/SERPINB1/NLRP3/RIPK2	16
GO:0032652	regulation of interleukin-1 production	16/665	128/18722	1.24236325764997e-05	0.000224528923291649	TREM2/ACP5/CLEC7A/ERRFI1/CARD16/LILRA5/CD36/MYD88/PYCARD/TNFAIP3/ANXA1/EGR1/TYROBP/SERPINB1/NLRP3/RIPK2	16
GO:0030890	positive regulation of B cell proliferation	9/665	42/18722	1.32877834618305e-05	0.000237554977716899	GPR183/CD74/TNFSF13B/MIF/IRS2/CDKN1A/TFRC/EPHB2/CD81	9
GO:0046596	regulation of viral entry into host cell	9/665	42/18722	1.32877834618305e-05	0.000237554977716899	HLA-DRB1/LGALS1/IFITM1/CD74/TRIM22/IFITM3/IFITM2/GSN/LY6E	9
GO:2000404	regulation of T cell migration	9/665	42/18722	1.32877834618305e-05	0.000237554977716899	ADAM8/ECM1/PYCARD/TNFRSF14/RHOA/WNK1/IL27RA/DOCK8/CXCL12	9
GO:0071675	regulation of mononuclear cell migration	15/665	115/18722	1.37727439281987e-05	0.000245342427681533	DUSP1/ADAM8/C5AR1/ECM1/LGALS3/MSN/PYCARD/TNFRSF14/RHOA/WNK1/IL27RA/SPI1/PTK2B/DOCK8/CXCL12	15
GO:0045765	regulation of angiogenesis	29/665	342/18722	1.46573187736282e-05	0.000260167408231901	CXCR4/VEGFA/GPNMB/CTSH/STAT1/BTG1/ALOX5/HK2/CXCL8/KLF4/PGK1/GLUL/PKM/ADM/C5AR1/ECM1/TNFAIP3/HMOX1/KLF2/EGLN1/RHOB/TNFSF12/GRN/ACVRL1/PTK2B/PIK3CB/CYP1B1/ANGPTL4/NRP1	29
GO:0051403	stress-activated MAPK cascade	23/665	239/18722	1.52916780140467e-05	0.000270461351351644	FCGR2B/TREM2/PAGE4/VEGFA/DUSP1/EIF2AK2/CLEC7A/NCF1/ZFP36/MYD88/PYCARD/RASSF2/TRIB1/EGFR/AIDA/LRRK2/SDCBP/MAP3K3/SPI1/PTK2B/MDFIC/PER1/RIPK2	23
GO:1905475	regulation of protein localization to membrane	19/665	175/18722	1.55331192692927e-05	0.000273757456625479	TREM2/DAB2/GSN/RAP1A/LGALS3/GBP1/ITGAM/KCNE1/EGFR/MMP14/KIF5B/STX3/ABI3/SQSTM1/EPHB2/TMEM59/CD81/ATP2C1/PRNP	19
GO:0009896	positive regulation of catabolic process	37/665	492/18722	1.56949330271051e-05	0.000275631862702164	NUPR1/TREM2/APOE/ADAM8/ZFP36L2/DAB2/TRIM22/SUMO2/BNIP3L/ZFP36/IRS2/HAMP/PIP4K2A/BNIP3/MSN/TNFAIP3/SMURF2/PTEN/HMOX1/DTX3L/TRIB1/RBX1/TNFSF12/LRRK2/PSMC6/PLK3/PTK2B/PIK3CB/TOB1/OAZ1/FBXL5/ABHD5/TMEM59/TIPARP/CD81/SMAD7/RIPK2	37
GO:0036230	granulocyte activation	9/665	43/18722	1.62803375783033e-05	0.00028354980005343	FCGR2B/CD300A/CXCL8/MYD88/ITGAM/PTAFR/GRN/SPI1/TYROBP	9
GO:0002720	positive regulation of cytokine production involved in immune response	11/665	65/18722	1.6316950264644e-05	0.00028354980005343	HLA-A/B2M/CD74/RSAD2/CLEC7A/HLA-F/CD36/TNFRSF14/HLA-E/NLRP3/CD81	11
GO:0070936	protein K48-linked ubiquitination	11/665	65/18722	1.6316950264644e-05	0.00028354980005343	IFI27/NMI/UBE2B/TNFAIP3/DTX3L/RBX1/UBE2D2/RNF187/RNF5/UBE2D1/UBE2Q2	11
GO:0045639	positive regulation of myeloid cell differentiation	14/665	103/18722	1.64855727049719e-05	0.000285481868793416	ISG15/HLA-DRB1/TREM2/CD74/JUN/STAT1/EVI2B/KLF10/FOS/HCLS1/TRIB1/TYROBP/RB1/HAX1	14
GO:0022604	regulation of cell morphogenesis	27/665	309/18722	1.68570849372979e-05	0.000290901778258232	CXCR4/VEGFA/LIMS1/ALDOA/S100A10/MYADM/CD44/MSN/RAC1/GBP1/PARVB/PDPN/ANXA1/FLNA/RHOA/RHOB/RHOC/EPB41/MYL12A/RND3/PTK2B/DIAPH1/CCL13/FN1/HEXB/CFL1/NRP1	27
GO:0032872	regulation of stress-activated MAPK cascade	20/665	192/18722	1.72851008978805e-05	0.000297255887413377	FCGR2B/TREM2/PAGE4/VEGFA/DUSP1/EIF2AK2/CLEC7A/NCF1/MYD88/PYCARD/RASSF2/EGFR/AIDA/SDCBP/MAP3K3/SPI1/PTK2B/MDFIC/PER1/RIPK2	20
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	6/665	17/18722	1.73771219929316e-05	0.000297807918292656	HLA-A/B2M/HLA-B/HLA-C/HLA-F/HLA-E	6
GO:0045621	positive regulation of lymphocyte differentiation	14/665	104/18722	1.84384359060141e-05	0.000313832282372911	HLA-DRB1/IL4I1/HLA-DRA/CD74/ADAM8/ANXA1/RHOA/NFKBIZ/IL7R/CD83/MMP14/CD86/NLRP3/RIPK2	14
GO:1903076	regulation of protein localization to plasma membrane	14/665	104/18722	1.84384359060141e-05	0.000313832282372911	TREM2/DAB2/LGALS3/GBP1/EGFR/MMP14/KIF5B/STX3/ABI3/SQSTM1/EPHB2/TMEM59/ATP2C1/PRNP	14
GO:0060759	regulation of response to cytokine stimulus	18/665	162/18722	1.88685163642305e-05	0.000320056403857425	ISG15/CXCR4/TREM2/CD74/OAS1/OAS3/IFIH1/KLF4/CARD16/ECM1/IRF7/PYCARD/TNFAIP3/PARP9/USP18/AGPAT2/TLR2/RIPK2	18
GO:0045582	positive regulation of T cell differentiation	13/665	91/18722	1.91060612201844e-05	0.000322983415865023	HLA-DRB1/IL4I1/HLA-DRA/CD74/ADAM8/ANXA1/RHOA/NFKBIZ/IL7R/CD83/CD86/NLRP3/RIPK2	13
GO:1901342	regulation of vasculature development	29/665	348/18722	2.03010298334518e-05	0.00034202073990595	CXCR4/VEGFA/GPNMB/CTSH/STAT1/BTG1/ALOX5/HK2/CXCL8/KLF4/PGK1/GLUL/PKM/ADM/C5AR1/ECM1/TNFAIP3/HMOX1/KLF2/EGLN1/RHOB/TNFSF12/GRN/ACVRL1/PTK2B/PIK3CB/CYP1B1/ANGPTL4/NRP1	29
GO:0051384	response to glucocorticoid	17/665	148/18722	2.073000848645e-05	0.000348068047897488	DDIT4/DUSP1/ZFP36L2/CALM1/ADM/ERRFI1/ZFP36/FOSB/FOS/ANXA1/RHOA/EGFR/PTAFR/CALM3/CDKN1A/KLF9/EIF4E	17
GO:0002604	regulation of dendritic cell antigen processing and presentation	5/665	11/18722	2.15337839865596e-05	0.000359137269842957	FCGR2B/SLC11A1/CD74/FGL2/CD68	5
GO:0098883	synapse pruning	5/665	11/18722	2.15337839865596e-05	0.000359137269842957	TREM2/C1QB/C1QC/ITGAM/C1QA	5
GO:0070302	regulation of stress-activated protein kinase signaling cascade	20/665	195/18722	2.16929158295125e-05	0.000360581243052431	FCGR2B/TREM2/PAGE4/VEGFA/DUSP1/EIF2AK2/CLEC7A/NCF1/MYD88/PYCARD/RASSF2/EGFR/AIDA/SDCBP/MAP3K3/SPI1/PTK2B/MDFIC/PER1/RIPK2	20
GO:0043542	endothelial cell migration	25/665	279/18722	2.25271287619153e-05	0.00037319943315573	VEGFA/APOE/KLF4/GLUL/CSNK2B/PTEN/PRKX/HMOX1/RAC1/ANXA1/RHOA/GPI/RHOB/TNFSF12/GRN/MAP3K3/ACVRL1/RAB13/PTK2B/PIK3CB/CYP1B1/RIN2/NR4A1/GPX1/NRP1	25
GO:0071887	leukocyte apoptotic process	14/665	106/18722	2.29644306024995e-05	0.000379180133204062	TSC22D3/CD74/ADAM8/MERTK/IRS2/LGALS3/IRF7/PTEN/ANXA1/HCLS1/IL7R/DOCK8/PIK3CB/CXCL12	14
GO:0032755	positive regulation of interleukin-6 production	13/665	93/18722	2.42382326704302e-05	0.00039440751235215	CD74/IFIH1/IL1RAP/CLEC7A/LILRA5/CD36/MYD88/PYCARD/AKIRIN2/PTAFR/TYROBP/TLR2/RIPK2	13
GO:0051591	response to cAMP	13/665	93/18722	2.42382326704302e-05	0.00039440751235215	LDHA/DUSP1/JUN/STAT1/AHR/FOSB/RAP1A/RAPGEF1/FOS/KCNE1/PTAFR/PTK2B/PER1	13
GO:0002711	positive regulation of T cell mediated immunity	10/665	56/18722	2.42834403983416e-05	0.00039440751235215	HLA-DRB1/HLA-A/HLA-DRA/B2M/RSAD2/HLA-B/HLA-F/HLA-E/NLRP3/CD81	10
GO:0032608	interferon-beta production	10/665	56/18722	2.42834403983416e-05	0.00039440751235215	ISG15/OAS2/OAS1/OAS3/IFIH1/NMI/IRF7/PYCARD/TLR2/RIPK2	10
GO:0032648	regulation of interferon-beta production	10/665	56/18722	2.42834403983416e-05	0.00039440751235215	ISG15/OAS2/OAS1/OAS3/IFIH1/NMI/IRF7/PYCARD/TLR2/RIPK2	10
GO:2000403	positive regulation of lymphocyte migration	8/665	35/18722	2.44260870708783e-05	0.000395432093623013	ADAM8/PYCARD/TNFRSF14/RHOA/WNK1/PTK2B/DOCK8/CXCL12	8
GO:0010952	positive regulation of peptidase activity	20/665	197/18722	2.51662090350685e-05	0.000406091100338606	CTSH/EGLN3/CLEC7A/PSME2/RPS27L/GSN/PYCARD/FAM162A/RHOA/AKIRIN2/CTSD/CYCS/TANK/GRN/S100A8/APH1A/FN1/GRAMD4/NLRP3/RIPK2	20
GO:0002224	toll-like receptor signaling pathway	15/665	121/18722	2.54964372607115e-05	0.000410088327461929	TREM2/CD300A/NFKBIA/OAS1/RSAD2/NMI/CD36/MYD88/IRF7/TNFAIP3/IFI35/GRAMD4/TLR2/WDFY1/RIPK2	15
GO:0031331	positive regulation of cellular catabolic process	33/665	427/18722	2.6131736083932e-05	0.000417603628093705	NUPR1/TREM2/APOE/ADAM8/ZFP36L2/DAB2/TRIM22/SUMO2/BNIP3L/ZFP36/IRS2/HAMP/PIP4K2A/BNIP3/MSN/TNFAIP3/PTEN/HMOX1/DTX3L/TRIB1/RBX1/LRRK2/PSMC6/PLK3/PTK2B/PIK3CB/TOB1/FBXL5/ABHD5/TMEM59/CD81/SMAD7/RIPK2	33
GO:0043254	regulation of protein-containing complex assembly	33/665	427/18722	2.6131736083932e-05	0.000417603628093705	ISG15/TREM2/VEGFA/CAPG/APOE/EIF2AK2/CLEC7A/MYADM/CD36/GSN/GMFG/ARPC4/MYD88/LGALS3/MSN/MAPRE1/PYCARD/GRB2/RAC1/DNAJC15/EIF4EBP1/RHOA/HCLS1/COTL1/RHOC/AIDA/TMSB10/PSMC6/PTK2B/TFRC/RB1/HAX1/IQGAP2	33
GO:0003158	endothelium development	16/665	136/18722	2.6759109101093e-05	0.00042625888536036	CXCR4/VEGFA/BTG1/MYADM/CSNK2B/RAP1A/MYD88/MSN/RAPGEF1/PDPN/RHOA/RHOB/EDF1/ACVRL1/GPX1/NRP1	16
GO:0000422	autophagy of mitochondrion	12/665	81/18722	2.74048754535583e-05	0.000432388034933919	HK2/BNIP3L/TSPO/MAP1LC3B/BNIP3/GABARAPL2/CISD2/WDR45B/SQSTM1/ATG3/WIPI2/HAX1	12
GO:0046209	nitric oxide metabolic process	12/665	81/18722	2.74048754535583e-05	0.000432388034933919	KLF4/ACP5/CLEC7A/DYNLL1/TSPO/CD36/RAC1/DDAH2/KLF2/PTK2B/CYP1B1/TLR2	12
GO:0061726	mitochondrion disassembly	12/665	81/18722	2.74048754535583e-05	0.000432388034933919	HK2/BNIP3L/TSPO/MAP1LC3B/BNIP3/GABARAPL2/CISD2/WDR45B/SQSTM1/ATG3/WIPI2/HAX1	12
GO:0050868	negative regulation of T cell activation	15/665	122/18722	2.81350433102855e-05	0.000442503687506706	FCGR2B/HLA-DRB1/IL4I1/GPNMB/CD300A/CD74/CEBPB/FGL2/LGALS3/TNFRSF14/ANXA1/LAG3/CD86/SMAD7/PRNP	15
GO:2000107	negative regulation of leukocyte apoptotic process	9/665	46/18722	2.89205925087147e-05	0.000453423800530953	TSC22D3/CD74/MERTK/IRS2/IRF7/HCLS1/IL7R/DOCK8/CXCL12	9
GO:1901224	positive regulation of NIK/NF-kappaB signaling	11/665	69/18722	2.92330762150979e-05	0.000456881725751688	TREM2/LIMS1/EIF2AK2/NMI/TERF2IP/RHOA/IFI35/EGFR/CD86/TLR2/PHB	11
GO:0042092	type 2 immune response	8/665	36/18722	3.04350933592791e-05	0.000474176846381245	CD74/RSAD2/ECM1/ANXA1/IL27RA/CD86/NLRP3/CD81	8
GO:0007044	cell-substrate junction assembly	13/665	95/18722	3.05380052305358e-05	0.000474293393736759	VEGFA/LIMS1/S100A10/PTEN/RAC1/RHOA/PLEC/DST/MMP14/ACVRL1/PTK2B/FN1/NRP1	13
GO:2001057	reactive nitrogen species metabolic process	12/665	82/18722	3.10815656341756e-05	0.000481231717139729	KLF4/ACP5/CLEC7A/DYNLL1/TSPO/CD36/RAC1/DDAH2/KLF2/PTK2B/CYP1B1/TLR2	12
GO:0071496	cellular response to external stimulus	27/665	320/18722	3.1309960059614e-05	0.000483262427007086	JUN/EIF2AK2/GLUL/NR4A2/ATF3/UPP1/SLC38A2/MAP1LC3B/KLF10/NAMPT/MYD88/BNIP3/GABARAPL2/HMOX1/RAC1/FOS/DNAJC15/EGFR/WDR45B/PLEC/MAP3K2/LRRK2/RRAGD/CDKN1A/HNRNPA1/WIPI2/CD68	27
GO:0018108	peptidyl-tyrosine phosphorylation	30/665	375/18722	3.18357477793319e-05	0.000489856552517893	TREM2/VEGFA/CD300A/CD74/EIF2AK2/SH3BP5/CLEC7A/MERTK/ERRFI1/MIF/LILRA5/CD44/NCF1/CD36/ABI1/SOCS3/TNFRSF14/PARP9/HCLS1/SAMSN1/EGFR/PTK2B/ARL2BP/IGF2/EPHB2/HAX1/CD81/RIPK2/PRNP/NRP1	30
GO:0008154	actin polymerization or depolymerization	21/665	217/18722	3.26770943953427e-05	0.000501250491187818	CAPG/MYADM/GSN/ANG/GMFG/ARPC4/PYCARD/GRB2/ABI1/RAC1/RHOA/HCLS1/COTL1/WIPF1/TMSB10/PTK2B/DIAPH1/HAX1/IQGAP2/CFL1/CXCL12	21
GO:0006091	generation of precursor metabolites and energy	36/665	490/18722	3.34375712695288e-05	0.000511337628337102	NUPR1/LDHA/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/TPI1/NCF1/SDHD/IRS2/SCO2/IDH1/GAPDH/BNIP3/PPP1CB/ENO1/BLOC1S1/PPP1R3B/ALDH2/DNAJC15/RHOA/DHRS3/GPI/PTGES3/PLEC/COA6/ENO2/PHLDA2/PGAM1/SDHB/CYCS/IGF2/COX5B/GALK1	36
GO:0043301	negative regulation of leukocyte degranulation	5/665	12/18722	3.58357293844148e-05	0.000546329984786937	FCGR2B/CD300A/HLA-F/HMOX1/SPI1	5
GO:0018212	peptidyl-tyrosine modification	30/665	378/18722	3.69362645694588e-05	0.000561386039480765	TREM2/VEGFA/CD300A/CD74/EIF2AK2/SH3BP5/CLEC7A/MERTK/ERRFI1/MIF/LILRA5/CD44/NCF1/CD36/ABI1/SOCS3/TNFRSF14/PARP9/HCLS1/SAMSN1/EGFR/PTK2B/ARL2BP/IGF2/EPHB2/HAX1/CD81/RIPK2/PRNP/NRP1	30
GO:0007519	skeletal muscle tissue development	17/665	155/18722	3.77798376544382e-05	0.000572456686410238	NUPR1/SAP30/YBX3/ATF3/VAMP5/CITED2/FOS/RHOA/EGR1/PLEC/GPCPD1/COPS2/IGF2/RB1/NR4A1/MYL6/GPX1	17
GO:1990868	response to chemokine	13/665	97/18722	3.82229800833578e-05	0.000575661245497844	CXCR4/TREM2/DUSP1/CXCL8/RHOA/WNK1/CXCL2/CXCL3/PTK2B/DOCK8/PPBP/CCL13/CXCL12	13
GO:1990869	cellular response to chemokine	13/665	97/18722	3.82229800833578e-05	0.000575661245497844	CXCR4/TREM2/DUSP1/CXCL8/RHOA/WNK1/CXCL2/CXCL3/PTK2B/DOCK8/PPBP/CCL13/CXCL12	13
GO:0032722	positive regulation of chemokine production	11/665	71/18722	3.84862412453376e-05	0.00057787498184087	CD74/EIF2AK2/OAS1/OAS3/CLEC7A/MYD88/PYCARD/HMOX1/EGR1/TLR2/RIPK2	11
GO:0031667	response to nutrient levels	35/665	474/18722	3.87092536722591e-05	0.000579472863708216	LDHA/PAGE4/APOE/JUN/STAT1/EIF2AK2/GLUL/ACSL1/ADM/ATF3/UPP1/SOD2/TSPO/ZFP36/HAMP/SLC38A2/MAP1LC3B/KLF10/NAMPT/BNIP3/GABARAPL2/PTEN/HMOX1/DNAJC15/EIF4EBP1/EGFR/WDR45B/PLEC/KRT18/LRRK2/RRAGD/CDKN1A/HNRNPA1/WIPI2/CD68	35
GO:0033673	negative regulation of kinase activity	22/665	237/18722	4.04969639741786e-05	0.000604414147002005	APOE/CD300A/DUSP1/SH3BP5/ERRFI1/GNAQ/IRS2/PIP4K2A/PYCARD/TNFAIP3/PTEN/RGS2/TRIB1/PLEC/AIDA/WNK1/CDKN1A/RB1/PIK3CB/EPHB2/AKT1S1/CDKN1C	22
GO:0050673	epithelial cell proliferation	33/665	437/18722	4.13698305626288e-05	0.000615592987713369	NUPR1/VEGFA/B2M/APOE/SULF2/STAT1/JAML/ALOX5/GLUL/CEBPB/ERRFI1/C5AR1/ECM1/ZFP36/ANG/TNFAIP3/PTEN/PRKX/HMOX1/EGFR/TNFSF12/GRN/MMP14/ACVRL1/KLF9/IGF2/RB1/NR4A1/SERPINB1/CXCL12/CDKN1C/GPX1/NRP1	33
GO:0032642	regulation of chemokine production	13/665	98/18722	4.26613961180136e-05	0.000632916831959784	TREM2/CD74/EIF2AK2/OAS1/OAS3/KLF4/CLEC7A/MYD88/PYCARD/HMOX1/EGR1/TLR2/RIPK2	13
GO:0032729	positive regulation of interferon-gamma production	11/665	72/18722	4.39898596295817e-05	0.000650683340354229	ISG15/SLC11A1/HLA-A/HLA-DPB1/HLA-DPA1/CLEC7A/PYCARD/IRF8/IL27RA/EBI3/RIPK2	11
GO:0002262	myeloid cell homeostasis	17/665	157/18722	4.45237960567625e-05	0.000656626903270356	ISG15/VEGFA/B2M/STAT1/MERTK/ZFP36/HAMP/MAFB/CITED2/HMOX1/ANXA1/KLF2/HCLS1/GPI/SPI1/RB1/PIK3CB	17
GO:0032535	regulation of cellular component size	30/665	382/18722	4.48879918598889e-05	0.000660039406933869	VEGFA/CAPG/APOE/MYADM/DPYSL2/PPP1R15A/GSN/GMFG/ARPC4/RIN3/MSN/PYCARD/GRB2/PTEN/RAC1/TMEM123/RHOA/HCLS1/COTL1/LAMTOR5/IL7R/TMSB10/PTK2B/KCNMA1/FN1/AKT1S1/HAX1/IQGAP2/CXCL12/NRP1	30
GO:0031663	lipopolysaccharide-mediated signaling pathway	10/665	60/18722	4.52514477159425e-05	0.000663420929640809	NFKBIA/CARD16/CD36/MYD88/TNFAIP3/TRIB1/PTAFR/SPI1/TLR2/RIPK2	10
GO:0009595	detection of biotic stimulus	8/665	38/18722	4.61966833365233e-05	0.000675286812301532	HLA-DRB1/HLA-A/TREM2/HLA-B/CLEC7A/TSPO/TLR2/NLRP3	8
GO:0002708	positive regulation of lymphocyte mediated immunity	14/665	113/18722	4.74209710498206e-05	0.000691150223218792	HLA-DRB1/HLA-A/HLA-DRA/TREM2/B2M/RSAD2/HLA-B/HLA-F/CADM1/LAG3/HLA-E/TFRC/NLRP3/CD81	14
GO:0038061	NIK/NF-kappaB signaling	16/665	143/18722	4.97520258867457e-05	0.000723004586716742	TREM2/LIMS1/NFKBIA/EIF2AK2/NMI/TERF2IP/RASSF2/RHOA/LITAF/IFI35/EGFR/SPI1/CD86/TLR2/PHB/NLRP3	16
GO:0043410	positive regulation of MAPK cascade	35/665	480/18722	5.00050126060949e-05	0.000724562427557702	FCGR2B/HLA-DRB1/TREM2/VEGFA/GPR183/GPNMB/APOE/CD74/ADAM8/EIF2AK2/CLEC7A/C5AR1/MIF/LILRA5/CD44/NCF1/CD36/RAP1A/MYD88/PYCARD/RASSF2/PTEN/EGFR/GLIPR2/LRRK2/SDCBP/MAP3K3/SPI1/PTK2B/IGF2/CCL13/PHB/CD81/RIPK2/NRP1	35
GO:1903008	organelle disassembly	14/665	114/18722	5.23274054134101e-05	0.000756009316583279	HK2/BNIP3L/TSPO/MAP1LC3B/BNIP3/GABARAPL2/CISD2/WDR45B/PLK3/KIF5B/SQSTM1/ATG3/WIPI2/HAX1	14
GO:0010821	regulation of mitochondrion organization	16/665	144/18722	5.41663801863439e-05	0.000778210571552237	TREM2/BNIP3L/TSPO/INF2/BNIP3/PYCARD/FAM162A/RALA/LMNA/VAT1/LRRK2/PLAUR/SQSTM1/TFRC/HAX1/GPX1	16
GO:0045860	positive regulation of protein kinase activity	30/665	386/18722	5.43587438212593e-05	0.000778210571552237	SLC11A1/VEGFA/CD300A/ADAM8/CALM1/ACSL1/LILRA5/NCF1/ANG/RAP1A/ABI1/RASSF2/CCNY/RHOA/EGR1/DAZAP2/EGFR/LRRK2/WNK1/TAB2/CALM3/CDKN1A/TXN/CAMK1/CD86/PTK2B/IGF2/MMD/PHB/PRNP	30
GO:0001916	positive regulation of T cell mediated cytotoxicity	7/665	29/18722	5.449039816905e-05	0.000778210571552237	HLA-DRB1/HLA-A/HLA-DRA/B2M/HLA-B/HLA-F/HLA-E	7
GO:2000406	positive regulation of T cell migration	7/665	29/18722	5.449039816905e-05	0.000778210571552237	ADAM8/PYCARD/TNFRSF14/RHOA/WNK1/DOCK8/CXCL12	7
GO:0002347	response to tumor cell	8/665	39/18722	5.63258303630326e-05	0.000797548082348353	HLA-DRB1/IL4I1/HLA-A/TXNIP/KLF4/AHR/SPI1/ABI3	8
GO:0032728	positive regulation of interferon-beta production	8/665	39/18722	5.63258303630326e-05	0.000797548082348353	ISG15/OAS2/OAS1/OAS3/IFIH1/IRF7/TLR2/RIPK2	8
GO:0045622	regulation of T-helper cell differentiation	8/665	39/18722	5.63258303630326e-05	0.000797548082348353	HLA-DRB1/HLA-DRA/ANXA1/NFKBIZ/CD86/NLRP3/SMAD7/RIPK2	8
GO:0046638	positive regulation of alpha-beta T cell differentiation	9/665	50/18722	5.79446320661857e-05	0.00081813869707086	HLA-DRB1/HLA-DRA/ANXA1/RHOA/NFKBIZ/CD83/CD86/NLRP3/RIPK2	9
GO:0150115	cell-substrate junction organization	13/665	101/18722	5.87784936530952e-05	0.000827561227920349	VEGFA/LIMS1/S100A10/PTEN/RAC1/RHOA/PLEC/DST/MMP14/ACVRL1/PTK2B/FN1/NRP1	13
GO:0032613	interleukin-10 production	10/665	62/18722	6.05433759597985e-05	0.000840504409274298	FCGR2B/ISG15/HLA-DRB1/TREM2/CLEC7A/LILRA5/PYCARD/CD83/TYROBP/TLR2	10
GO:0032623	interleukin-2 production	10/665	62/18722	6.05433759597985e-05	0.000840504409274298	CLEC7A/ZFP36/TNFAIP3/GBP1/ANXA1/LAG3/CD83/CD86/RIPK2/PRNP	10
GO:0032653	regulation of interleukin-10 production	10/665	62/18722	6.05433759597985e-05	0.000840504409274298	FCGR2B/ISG15/HLA-DRB1/TREM2/CLEC7A/LILRA5/PYCARD/CD83/TYROBP/TLR2	10
GO:0032663	regulation of interleukin-2 production	10/665	62/18722	6.05433759597985e-05	0.000840504409274298	CLEC7A/ZFP36/TNFAIP3/GBP1/ANXA1/LAG3/CD83/CD86/RIPK2/PRNP	10
GO:0045428	regulation of nitric oxide biosynthetic process	10/665	62/18722	6.05433759597985e-05	0.000840504409274298	KLF4/ACP5/CLEC7A/DYNLL1/TSPO/CD36/RAC1/DDAH2/KLF2/PTK2B	10
GO:0045089	positive regulation of innate immune response	15/665	131/18722	6.50097249889311e-05	0.000899995357089102	ADAM8/PLSCR1/CLEC7A/NMI/HLA-F/CADM1/IRF7/PYCARD/PARP9/IFI35/LAG3/AKIRIN2/SPI1/HLA-E/TYROBP	15
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	9/665	51/18722	6.81702377498362e-05	0.000941128004490794	HLA-DRB1/HLA-DRA/ANXA1/NFKBIZ/CD83/CD86/NLRP3/SMAD7/RIPK2	9
GO:0031668	cellular response to extracellular stimulus	22/665	246/18722	7.08685278216909e-05	0.000975669205744609	JUN/EIF2AK2/GLUL/NR4A2/ATF3/UPP1/SLC38A2/MAP1LC3B/KLF10/NAMPT/GABARAPL2/HMOX1/FOS/DNAJC15/WDR45B/PLEC/LRRK2/RRAGD/CDKN1A/HNRNPA1/WIPI2/CD68	22
GO:0071356	cellular response to tumor necrosis factor	21/665	229/18722	7.17943351658391e-05	0.000985684656834862	LIMS1/NFKBIA/ZFP36L2/STAT1/TNFSF13B/CXCL8/YBX3/CARD16/ZFP36/HAMP/PYCARD/TNFAIP3/GBP1/TNFRSF14/KLF2/KRT18/TANK/CD58/PTK2B/GBP3/CCL13	21
GO:0006809	nitric oxide biosynthetic process	11/665	76/18722	7.33113472333092e-05	0.000998239440409718	KLF4/ACP5/CLEC7A/DYNLL1/TSPO/CD36/RAC1/DDAH2/KLF2/PTK2B/CYP1B1	11
GO:0031100	animal organ regeneration	11/665	76/18722	7.33113472333092e-05	0.000998239440409718	SULF2/CEBPB/ADM/C5AR1/CSNK2B/HAMP/RAP1A/HMOX1/EGFR/CDKN1A/CXCL12	11
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	11/665	76/18722	7.33113472333092e-05	0.000998239440409718	NUPR1/DDIT4/CD74/RPS27L/MIF/CD44/PYCARD/SHISA5/RRM2B/CDKN1A/ZNF385A	11
GO:0097530	granulocyte migration	16/665	148/18722	7.54636914187019e-05	0.00102473919768019	CD300A/CD74/ADAM8/JAML/CXCL8/C5AR1/MYD88/LGALS3/TREM1/RAC1/ANXA1/CXCL2/S100A8/CXCL3/PPBP/CCL13	16
GO:0062197	cellular response to chemical stress	27/665	337/18722	7.62253895584609e-05	0.00103226208748106	TREM2/PAGE4/JUN/ALOX5/KLF4/YBX3/NR4A2/ERRFI1/SOD2/NCF1/TSPO/CD36/BNIP3/TNFAIP3/MCL1/HMOX1/FOS/ANXA1/KLF2/RHOB/EGFR/PLEC/LRRK2/TXN/CYP1B1/CPEB2/GPX1	27
GO:0051101	regulation of DNA binding	14/665	118/18722	7.6665859784405e-05	0.0010354057693709	JUN/NFKBIA/CALM1/KLF4/CSNK2B/HMOX1/LAMTOR5/PLAUR/CALM3/EDF1/TXN/RB1/SUMO3/RSF1	14
GO:0080164	regulation of nitric oxide metabolic process	10/665	64/18722	8.0024124544943e-05	0.00107637861148862	KLF4/ACP5/CLEC7A/DYNLL1/TSPO/CD36/RAC1/DDAH2/KLF2/PTK2B	10
GO:0071248	cellular response to metal ion	19/665	197/18722	8.01328141349679e-05	0.00107637861148862	JUND/B2M/JUN/FBP1/NCF1/TSPO/FOSB/MT1X/BNIP3/JUNB/HMOX1/ALOX5AP/FOS/EGFR/LRRK2/WNK1/CACYBP/HSD17B1/PRNP	19
GO:0048545	response to steroid hormone	27/665	339/18722	8.42130850812116e-05	0.00112813755486151	DDIT4/DUSP1/TXNIP/YWHAH/ZFP36L2/DAB2/CALM1/ADM/ERRFI1/TSPO/ZFP36/FOSB/IDH1/FOS/ANXA1/RHOA/GPI/PTGES3/EGFR/PTAFR/CALM3/CDKN1A/KLF9/EIF4E/TLR2/PHB/PER1	27
GO:0050864	regulation of B cell activation	19/665	198/18722	8.57638007132865e-05	0.00114582282135762	FCGR2B/IL4I1/GPR183/CD300A/CD74/ZFP36L2/TNFSF13B/MIF/AHR/IRS2/TNFAIP3/SAMSN1/IL27RA/MMP14/CDKN1A/TYROBP/TFRC/EPHB2/CD81	19
GO:0002275	myeloid cell activation involved in immune response	12/665	91/18722	8.85113411312366e-05	0.00117936022901406	TREM2/CD300A/NMI/MYD88/PYCARD/HMOX1/ITGAM/IFI35/PTAFR/GRN/SPI1/TYROBP	12
GO:0060538	skeletal muscle organ development	17/665	166/18722	8.9878867678134e-05	0.00119165664197569	NUPR1/SAP30/YBX3/ATF3/VAMP5/CITED2/FOS/RHOA/EGR1/PLEC/GPCPD1/COPS2/IGF2/RB1/NR4A1/MYL6/GPX1	17
GO:0071900	regulation of protein serine/threonine kinase activity	28/665	359/18722	8.9913730531365e-05	0.00119165664197569	VEGFA/HERC5/APOE/CD300A/DUSP1/ADAM8/CALM1/ACSL1/PYCARD/TNFAIP3/PTEN/CCNY/RHOA/RGS2/DAZAP2/TRIB1/EGFR/AIDA/LRRK2/CALM3/CDKN1A/CAMK1/PTK2B/IGF2/RB1/PIK3CB/CCNI/CDKN1C	28
GO:0071677	positive regulation of mononuclear cell migration	10/665	65/18722	9.1607247141361e-05	0.00121087238907597	ADAM8/LGALS3/PYCARD/TNFRSF14/RHOA/WNK1/SPI1/PTK2B/DOCK8/CXCL12	10
GO:0002707	negative regulation of lymphocyte mediated immunity	9/665	53/18722	9.32157954636231e-05	0.00122886605690771	FCGR2B/IL4I1/HLA-A/HLA-B/AHR/HLA-F/IL7R/HLA-E/SMAD7	9
GO:0051346	negative regulation of hydrolase activity	29/665	379/18722	9.48147154416082e-05	0.00124663792525077	VEGFA/APOC1/TIMP1/KLF4/IFI6/CARD16/PPP1R15A/ECM1/SERPING1/CD44/BST2/LGALS3/GAPDH/CSTB/ANXA1/RGS2/GPI/LAMTOR5/EGLN1/LRRK2/WNK1/PLAUR/ANXA2/NR4A1/ANGPTL4/CPEB2/SERPINB1/PRNP/GPX1	29
GO:0031960	response to corticosteroid	17/665	167/18722	9.68339474785633e-05	0.00126648610254858	DDIT4/DUSP1/ZFP36L2/CALM1/ADM/ERRFI1/ZFP36/FOSB/FOS/ANXA1/RHOA/EGFR/PTAFR/CALM3/CDKN1A/KLF9/EIF4E	17
GO:1903034	regulation of response to wounding	17/665	167/18722	9.68339474785633e-05	0.00126648610254858	CXCR4/CD9/APOE/ALOX5/KLF4/CLEC7A/SERPING1/CD36/TNFAIP3/PTEN/ANXA1/FLNA/GRN/PLAU/ANXA2/SIGLEC10/EPHB2	17
GO:0070374	positive regulation of ERK1 and ERK2 cascade	20/665	217/18722	9.88180501166978e-05	0.00128904385585299	HLA-DRB1/TREM2/GPR183/GPNMB/APOE/CD74/C5AR1/MIF/CD44/CD36/RAP1A/PYCARD/PTEN/EGFR/GLIPR2/PTK2B/CCL13/PHB/RIPK2/NRP1	20
GO:0051092	positive regulation of NF-kappaB transcription factor activity	16/665	152/18722	0.000103783183966483	0.00134876250791733	ADAM8/EIF2AK2/IL1RAP/TRIM22/CLEC7A/CARD16/CD36/TERF2IP/MYD88/PYCARD/LAMTOR5/S100A8/TFRC/TLR2/NLRP3/RIPK2	16
GO:0050678	regulation of epithelial cell proliferation	29/665	381/18722	0.000103938841153388	0.00134876250791733	NUPR1/VEGFA/B2M/APOE/SULF2/STAT1/JAML/ALOX5/GLUL/ERRFI1/C5AR1/ECM1/ZFP36/ANG/TNFAIP3/PTEN/HMOX1/EGFR/TNFSF12/GRN/ACVRL1/KLF9/IGF2/RB1/NR4A1/CXCL12/CDKN1C/GPX1/NRP1	29
GO:0034612	response to tumor necrosis factor	22/665	253/18722	0.000107105719770689	0.00138623809182376	LIMS1/NFKBIA/ZFP36L2/STAT1/TNFSF13B/CXCL8/YBX3/CARD16/ZFP36/CXCL16/HAMP/PYCARD/TNFAIP3/GBP1/TNFRSF14/KLF2/KRT18/TANK/CD58/PTK2B/GBP3/CCL13	22
GO:0043433	negative regulation of DNA-binding transcription factor activity	18/665	185/18722	0.0001094763364272	0.00141075211418474	NUPR1/NFKBIA/ADORA3/KLF4/TMIGD3/BHLHE40/PYCARD/TNFAIP3/HMOX1/FLNA/EGLN1/TRIB1/SPI1/RB1/CYP1B1/NLRP3/SMAD7/PRNP	18
GO:0045185	maintenance of protein location	12/665	93/18722	0.000109567468023201	0.00141075211418474	SRGN/NFKBIA/HK2/TSPO/GSN/FLNA/FBN2/INSIG2/TMSB10/TXN/ARL2BP/VPS13A	12
GO:1990266	neutrophil migration	14/665	122/18722	0.000110320333575433	0.00141677534333308	CD74/ADAM8/JAML/CXCL8/C5AR1/MYD88/LGALS3/TREM1/RAC1/CXCL2/S100A8/CXCL3/PPBP/CCL13	14
GO:0097191	extrinsic apoptotic signaling pathway	20/665	219/18722	0.000112083548408293	0.00143570937007531	IFI27/IFI6/ATF3/SKIL/LGALS3/PYCARD/PEA15/TNFAIP3/MCL1/PTEN/HMOX1/LMNA/BLOC1S2/TNFSF12/KRT18/SPI1/G0S2/BCL2A1/GPX1/NRP1	20
GO:0034142	toll-like receptor 4 signaling pathway	8/665	43/18722	0.000117136894315465	0.00149658191451893	TREM2/NFKBIA/OAS1/NMI/TNFAIP3/IFI35/WDFY1/RIPK2	8
GO:0050765	negative regulation of phagocytosis	6/665	23/18722	0.000118119848198382	0.00150142108835284	FCGR2B/CD300A/PLSCR1/PTEN/ATG3/TLR2	6
GO:1903306	negative regulation of regulated secretory pathway	6/665	23/18722	0.000118119848198382	0.00150142108835284	FCGR2B/CD300A/HLA-F/RAP1A/HMOX1/SPI1	6
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	10/665	67/18722	0.000119073561697366	0.00150968265723446	HLA-DRB1/HLA-DRA/ANXA1/NFKBIZ/CD83/CD86/NLRP3/CD81/SMAD7/RIPK2	10
GO:0051702	biological process involved in interaction with symbiont	12/665	94/18722	0.000121616960760343	0.00153800583964098	SAP30/APOE/IFI27/JUN/MYD88/GAPDH/TREM1/FN1/PHB/ZBED1/CFL1/GPX1	12
GO:0030852	regulation of granulocyte differentiation	5/665	15/18722	0.000124323144473657	0.00156426842540272	EVI2B/C1QC/HCLS1/TRIB1/HAX1	5
GO:0090594	inflammatory response to wounding	5/665	15/18722	0.000124323144473657	0.00156426842540272	ALOX5/TIMP1/HMOX1/GRN/SIGLEC10	5
GO:0010810	regulation of cell-substrate adhesion	20/665	221/18722	0.000126899475019482	0.00159265250213845	LGALS1/VEGFA/LIMS1/S100A10/MYADM/CD36/PTEN/RAC1/GBP1/PDPN/FLNA/RHOA/MMP14/PLAU/ACVRL1/PTK2B/PIK3CB/FN1/RIN2/NRP1	20
GO:0002335	mature B cell differentiation	7/665	33/18722	0.000131815755714749	0.00163372644863417	FCGR2B/LGALS1/GPR183/IRF8/SPI1/PTK2B/CMTM7	7
GO:0032633	interleukin-4 production	7/665	33/18722	0.000131815755714749	0.00163372644863417	HLA-DRB1/IL1RAP/CEBPB/CD83/CD86/HLA-E/NLRP3	7
GO:0032673	regulation of interleukin-4 production	7/665	33/18722	0.000131815755714749	0.00163372644863417	HLA-DRB1/IL1RAP/CEBPB/CD83/CD86/HLA-E/NLRP3	7
GO:0045920	negative regulation of exocytosis	7/665	33/18722	0.000131815755714749	0.00163372644863417	FCGR2B/CD300A/HLA-F/RAP1A/HMOX1/ANXA1/SPI1	7
GO:0046685	response to arsenic-containing substance	7/665	33/18722	0.000131815755714749	0.00163372644863417	ATF3/SLC38A2/PTEN/HMOX1/CDKN1A/HNRNPA1/CPEB2	7
GO:0007599	hemostasis	20/665	222/18722	0.000134936099649711	0.0016635764366547	CD9/APOE/PLSCR1/MERTK/GNAQ/SERPING1/CD36/CLIC1/PDPN/FLNA/GPI/F13A1/PLAUR/MYL12A/PLAU/VKORC1/ANXA2/PIK3CB/EPHB2/FN1	20
GO:0046637	regulation of alpha-beta T cell differentiation	10/665	68/18722	0.000135228346158652	0.0016635764366547	HLA-DRB1/HLA-DRA/ANXA1/RHOA/NFKBIZ/CD83/CD86/NLRP3/SMAD7/RIPK2	10
GO:0046686	response to cadmium ion	10/665	68/18722	0.000135228346158652	0.0016635764366547	B2M/JUN/SOD2/NCF1/MT1X/HMOX1/FOS/GPI/EGFR/PRNP	10
GO:0009267	cellular response to starvation	16/665	156/18722	0.000140996088637604	0.00173024829760221	JUN/EIF2AK2/GLUL/ATF3/UPP1/SLC38A2/MAP1LC3B/KLF10/GABARAPL2/DNAJC15/WDR45B/LRRK2/RRAGD/CDKN1A/HNRNPA1/WIPI2	16
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	6/665	24/18722	0.000152791122125451	0.00186610887588468	FCGR2B/HLA-A/HLA-B/HLA-F/IL7R/HLA-E	6
GO:0060193	positive regulation of lipase activity	10/665	69/18722	0.000153193646149084	0.00186610887588468	C5AR1/GNAQ/ANG/RHOA/EGFR/RHOC/PTAFR/CD86/PHB/ABHD5	10
GO:1904377	positive regulation of protein localization to cell periphery	10/665	69/18722	0.000153193646149084	0.00186610887588468	TREM2/LGALS3/EGFR/EPB41/KIF5B/STX3/SQSTM1/EPHB2/ATP2C1/PRNP	10
GO:0030851	granulocyte differentiation	7/665	34/18722	0.000160949248786803	0.00194154797686993	EVI2B/C1QC/CITED2/HCLS1/TRIB1/SPI1/HAX1	7
GO:0044319	wound healing, spreading of cells	7/665	34/18722	0.000160949248786803	0.00194154797686993	CD44/PTEN/PDPN/FLNA/RHOA/RHOC/ACVRL1	7
GO:0055094	response to lipoprotein particle	7/665	34/18722	0.000160949248786803	0.00194154797686993	TREM2/CD9/APOE/CD36/MYD88/CD81/CD68	7
GO:0090505	epiboly involved in wound healing	7/665	34/18722	0.000160949248786803	0.00194154797686993	CD44/PTEN/PDPN/FLNA/RHOA/RHOC/ACVRL1	7
GO:0043367	CD4-positive, alpha-beta T cell differentiation	11/665	83/18722	0.000165084704835974	0.00198661254972104	HLA-DRB1/HLA-DRA/GPR183/RSAD2/ANXA1/NFKBIZ/CD83/CD86/NLRP3/SMAD7/RIPK2	11
GO:0060760	positive regulation of response to cytokine stimulus	9/665	57/18722	0.000166776268076502	0.0020021208993725	CXCR4/TREM2/CD74/IFIH1/IRF7/PARP9/AGPAT2/TLR2/RIPK2	9
GO:0032609	interferon-gamma production	13/665	112/18722	0.000171347130276756	0.00204710393623913	ISG15/SLC11A1/HLA-DRB1/HLA-A/HLA-DPB1/HLA-DPA1/CLEC7A/PYCARD/IRF8/IL27RA/EBI3/RIPK2/PRNP	13
GO:0032649	regulation of interferon-gamma production	13/665	112/18722	0.000171347130276756	0.00204710393623913	ISG15/SLC11A1/HLA-DRB1/HLA-A/HLA-DPB1/HLA-DPA1/CLEC7A/PYCARD/IRF8/IL27RA/EBI3/RIPK2/PRNP	13
GO:0002830	positive regulation of type 2 immune response	5/665	16/18722	0.00017556471226677	0.00208745602862642	CD74/RSAD2/CD86/NLRP3/CD81	5
GO:2000765	regulation of cytoplasmic translation	5/665	16/18722	0.00017556471226677	0.00208745602862642	PKM/YBX3/CNBP/ZNF385A/CPEB2	5
GO:0097061	dendritic spine organization	11/665	84/18722	0.00018397268252556	0.00218220580465879	FCGR2B/TREM2/APOE/TANC2/PTEN/LRRK2/ABI3/EPHB2/CFL1/SIPA1L1/PRNP	11
GO:0001952	regulation of cell-matrix adhesion	14/665	128/18722	0.000184602450512979	0.00218446233107025	VEGFA/LIMS1/S100A10/CD36/PTEN/RAC1/RHOA/MMP14/PLAU/ACVRL1/PTK2B/PIK3CB/RIN2/NRP1	14
GO:0002253	activation of immune response	28/665	375/18722	0.000187574735036368	0.00221436207394477	FCGR2B/HLA-DRB1/HLA-DQB1/FPR3/HLA-A/TREM2/HLA-DPB1/CD300A/MYO1G/PLSCR1/CLEC7A/C5AR1/SERPING1/CFD/C1QB/RAP1A/LGALS3/C1QC/PYCARD/GBP1/NFKBIZ/WNK1/TYROBP/PHB/CD81/RIPK2/PRNP/C1QA	28
GO:0033135	regulation of peptidyl-serine phosphorylation	15/665	144/18722	0.000190086165352713	0.00223869251612081	VEGFA/DDIT4/MIF/CD44/TERF2IP/RASSF2/PTEN/HCLS1/EGFR/TXN/CAMK1/TFRC/HAX1/SMAD7/RIPK2	15
GO:0098581	detection of external biotic stimulus	6/665	25/18722	0.000195042876179894	0.00227593379085082	HLA-DRB1/HLA-A/TREM2/HLA-B/CLEC7A/TLR2	6
GO:1903901	negative regulation of viral life cycle	6/665	25/18722	0.000195042876179894	0.00227593379085082	IFITM1/IFITM3/IFITM2/BST2/GSN/LY6E	6
GO:0090504	epiboly	7/665	35/18722	0.000195080039215785	0.00227593379085082	CD44/PTEN/PDPN/FLNA/RHOA/RHOC/ACVRL1	7
GO:0097421	liver regeneration	7/665	35/18722	0.000195080039215785	0.00227593379085082	SULF2/CEBPB/CSNK2B/HAMP/RAP1A/HMOX1/EGFR	7
GO:0010631	epithelial cell migration	27/665	357/18722	0.000197592037223406	0.00229908310144377	VEGFA/APOE/CTSH/KLF4/GLUL/CSNK2B/PTEN/PRKX/HMOX1/RAC1/ANXA1/RHOA/GPI/RHOB/GLIPR2/TNFSF12/GRN/MAP3K3/ACVRL1/RAB13/PTK2B/PIK3CB/CYP1B1/RIN2/NR4A1/GPX1/NRP1	27
GO:0030100	regulation of endocytosis	19/665	211/18722	0.000197989450184695	0.00229908310144377	TREM2/VEGFA/B2M/APOE/CD300A/APOC1/DAB2/CALM1/CD36/LGALS3/RIN3/RAC1/RUFY1/LRRK2/SDCBP/CALM3/ANXA2/PIK3CB/RAB31	19
GO:0006469	negative regulation of protein kinase activity	19/665	212/18722	0.00021043825004651	0.00243794429541061	APOE/CD300A/DUSP1/SH3BP5/ERRFI1/GNAQ/PYCARD/TNFAIP3/PTEN/RGS2/TRIB1/PLEC/AIDA/CDKN1A/RB1/PIK3CB/EPHB2/AKT1S1/CDKN1C	19
GO:1901653	cellular response to peptide	27/665	359/18722	0.000216217568845154	0.00249907283060562	FCGR2B/VIM/TREM2/STAT1/KLF4/PKM/NR4A2/ERRFI1/RAB8A/CD36/IRS2/PIP4K2A/KLF10/NAMPT/GRB2/PTEN/SOCS3/KLF2/INSIG2/RAB13/IGF2/NR4A1/RAB31/CHMP5/CPEB2/RIPK2/PRNP	27
GO:0001836	release of cytochrome c from mitochondria	9/665	59/18722	0.000218699044754614	0.00251605151025563	JUN/IFI6/SOD2/BNIP3/PYCARD/FAM162A/LMNA/PLAUR/GPX1	9
GO:0002820	negative regulation of adaptive immune response	9/665	59/18722	0.000218699044754614	0.00251605151025563	FCGR2B/IL4I1/AHR/HLA-F/TNFRSF14/SAMSN1/IL7R/IL27RA/SMAD7	9
GO:0043903	regulation of biological process involved in symbiotic interaction	10/665	72/18722	0.000219589573588845	0.00252046231116988	HLA-DRB1/LGALS1/IFITM1/CD74/CXCL8/TRIM22/IFITM3/IFITM2/GSN/LY6E	10
GO:0051651	maintenance of location in cell	19/665	213/18722	0.000223567318333663	0.00256020638736936	SRGN/APOE/HK2/CALM1/ERO1A/FTH1/TSPO/GSN/CLIC2/FTL/INSIG2/TMSB10/CALM3/S100A8/TXN/PTK2B/ARL2BP/DIAPH1/VPS13A	19
GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	8/665	47/18722	0.000224179030961879	0.00256130984800123	VEGFA/JUN/CEBPB/ATF3/CITED2/HMOX1/KLF2/EGR1	8
GO:0010950	positive regulation of endopeptidase activity	17/665	179/18722	0.000225307748978177	0.00256830163399435	CTSH/EGLN3/CLEC7A/PSME2/RPS27L/GSN/PYCARD/FAM162A/RHOA/AKIRIN2/CTSD/CYCS/S100A8/APH1A/GRAMD4/NLRP3/RIPK2	17
GO:0090132	epithelium migration	27/665	360/18722	0.000226102614717857	0.0025714645197889	VEGFA/APOE/CTSH/KLF4/GLUL/CSNK2B/PTEN/PRKX/HMOX1/RAC1/ANXA1/RHOA/GPI/RHOB/GLIPR2/TNFSF12/GRN/MAP3K3/ACVRL1/RAB13/PTK2B/PIK3CB/CYP1B1/RIN2/NR4A1/GPX1/NRP1	27
GO:0071402	cellular response to lipoprotein particle stimulus	7/665	36/18722	0.00023482192269839	0.00266453186258218	TREM2/CD9/APOE/CD36/MYD88/CD81/CD68	7
GO:0046683	response to organophosphorus	14/665	131/18722	0.000235716064539311	0.00266858505867967	LDHA/DUSP1/JUN/STAT1/AHR/FOSB/RAP1A/PTEN/RAPGEF1/FOS/KCNE1/PTAFR/PTK2B/PER1	14
GO:0043409	negative regulation of MAPK cascade	17/665	180/18722	0.000240786195653621	0.00271362220498525	TREM2/APOE/CD300A/DUSP1/KLF4/ATF3/ERRFI1/PTEN/GBP1/RGS2/AIDA/PIK3CB/EPHB2/DUSP2/PHB/PER1/DUSP6	17
GO:0048660	regulation of smooth muscle cell proliferation	17/665	180/18722	0.000240786195653621	0.00271362220498525	APOE/JUN/STAT1/KLF4/SOD2/ANG/NAMPT/MYD88/TNFAIP3/PTEN/HMOX1/RHOA/TRIB1/EGFR/PTAFR/CDKN1A/PHB	17
GO:0090713	immunological memory process	5/665	17/18722	0.000241476208214203	0.00271524152675246	HLA-DRB1/HLA-DRA/FGL2/TNFRSF14/CD81	5
GO:0002710	negative regulation of T cell mediated immunity	6/665	26/18722	0.000245996046450127	0.00275360439382237	FCGR2B/IL4I1/AHR/HLA-F/IL7R/SMAD7	6
GO:0060669	embryonic placenta morphogenesis	6/665	26/18722	0.000245996046450127	0.00275360439382237	ADM/ST14/GRB2/SOCS3/IGF2/SETD2	6
GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	9/665	60/18722	0.000249307444232027	0.00278439999513072	NFKBIA/OAS3/IFIH1/IRF7/TNFAIP3/DDX60/OASL/PHB/RIPK2	9
GO:0001776	leukocyte homeostasis	11/665	87/18722	0.000251986568903917	0.00280178845707969	TSC22D3/GPR183/CD74/TNFSF13B/MERTK/SKIL/TNFAIP3/ANXA1/SOS2/PIK3CB/CAMLG	11
GO:0031669	cellular response to nutrient levels	19/665	215/18722	0.00025199183909751	0.00280178845707969	JUN/EIF2AK2/GLUL/ATF3/UPP1/SLC38A2/MAP1LC3B/KLF10/NAMPT/GABARAPL2/HMOX1/DNAJC15/WDR45B/LRRK2/RRAGD/CDKN1A/HNRNPA1/WIPI2/CD68	19
GO:0007015	actin filament organization	31/665	441/18722	0.000254087965234123	0.00281878836431606	CAPG/MYO1G/ALDOA/S100A10/MYADM/GSN/ANG/GMFG/ARPC4/PYCARD/GRB2/ABI1/RAC1/FLNA/RHOA/HCLS1/COTL1/RHOB/PLEC/RHOC/WIPF1/TMSB10/RND3/PTK2B/DIAPH1/HAX1/IQGAP2/CFL1/MARCKS/CXCL12/NRP1	31
GO:0034599	cellular response to oxidative stress	23/665	288/18722	0.000265725185838385	0.0029369064461948	TREM2/PAGE4/JUN/ALOX5/KLF4/NR4A2/SOD2/NCF1/CD36/BNIP3/TNFAIP3/MCL1/HMOX1/FOS/ANXA1/KLF2/RHOB/EGFR/LRRK2/TXN/CYP1B1/CPEB2/GPX1	23
GO:0035710	CD4-positive, alpha-beta T cell activation	12/665	102/18722	0.000265917082653453	0.0029369064461948	HLA-DRB1/HLA-DRA/GPR183/RSAD2/ANXA1/NFKBIZ/CD83/CD86/NLRP3/CD81/SMAD7/RIPK2	12
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	4/665	10/18722	0.000279163532628408	0.00304746554019559	FGL2/LGALS3/HLA-DMB/CD81	4
GO:0002887	negative regulation of myeloid leukocyte mediated immunity	4/665	10/18722	0.000279163532628408	0.00304746554019559	FCGR2B/CD300A/HMOX1/SPI1	4
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	4/665	10/18722	0.000279163532628408	0.00304746554019559	EGLN3/P4HA1/ERO1A/EGLN1	4
GO:0070391	response to lipoteichoic acid	4/665	10/18722	0.000279163532628408	0.00304746554019559	TREM2/CD36/TLR2/RIPK2	4
GO:0071223	cellular response to lipoteichoic acid	4/665	10/18722	0.000279163532628408	0.00304746554019559	TREM2/CD36/TLR2/RIPK2	4
GO:0002369	T cell cytokine production	7/665	37/18722	0.000280832840525066	0.00304746554019559	HLA-A/B2M/RSAD2/HLA-F/NLRP3/CD81/SMAD7	7
GO:0002724	regulation of T cell cytokine production	7/665	37/18722	0.000280832840525066	0.00304746554019559	HLA-A/B2M/RSAD2/HLA-F/NLRP3/CD81/SMAD7	7
GO:0045730	respiratory burst	7/665	37/18722	0.000280832840525066	0.00304746554019559	SLC11A1/TREM2/CLEC7A/NCF1/RAC1/PGAM1/GRN	7
GO:0090130	tissue migration	27/665	365/18722	0.000281799119857095	0.00305128894485787	VEGFA/APOE/CTSH/KLF4/GLUL/CSNK2B/PTEN/PRKX/HMOX1/RAC1/ANXA1/RHOA/GPI/RHOB/GLIPR2/TNFSF12/GRN/MAP3K3/ACVRL1/RAB13/PTK2B/PIK3CB/CYP1B1/RIN2/NR4A1/GPX1/NRP1	27
GO:0007596	blood coagulation	19/665	217/18722	0.000283525413093745	0.00306199420010187	CD9/APOE/PLSCR1/MERTK/GNAQ/SERPING1/CD36/CLIC1/PDPN/FLNA/F13A1/PLAUR/MYL12A/PLAU/VKORC1/ANXA2/PIK3CB/EPHB2/FN1	19
GO:0006909	phagocytosis	24/665	308/18722	0.000284019985160354	0.00306199420010187	FCGR2B/SLC11A1/TREM2/CD300A/MYO1G/PLSCR1/CLEC7A/MERTK/CD36/GSN/RAP1A/MYD88/RAB20/MSR1/PYCARD/PTEN/RAC1/ANXA1/ITGAM/IRF8/ATG3/TYROBP/TLR2/RAB31	24
GO:0045446	endothelial cell differentiation	13/665	118/18722	0.000288957960016631	0.00310848714563345	CXCR4/VEGFA/BTG1/MYADM/RAP1A/MYD88/MSN/RAPGEF1/PDPN/EDF1/ACVRL1/GPX1/NRP1	13
GO:0030593	neutrophil chemotaxis	12/665	103/18722	0.000291455203980131	0.00312857961939795	CD74/JAML/CXCL8/C5AR1/LGALS3/TREM1/RAC1/CXCL2/S100A8/CXCL3/PPBP/CCL13	12
GO:0001959	regulation of cytokine-mediated signaling pathway	15/665	150/18722	0.000297550192179123	0.00318712167053932	ISG15/CXCR4/TREM2/CD74/OAS1/OAS3/CARD16/ECM1/IRF7/PYCARD/TNFAIP3/PARP9/USP18/AGPAT2/RIPK2	15
GO:0030225	macrophage differentiation	8/665	49/18722	0.000302059255860862	0.00322153326529717	HLA-DRB1/VEGFA/C1QC/HCLS1/TRIB1/SPI1/RB1/TLR2	8
GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	8/665	49/18722	0.000302059255860862	0.00322153326529717	ATF3/SKIL/LGALS3/PEA15/TNFAIP3/PTEN/HMOX1/GPX1	8
GO:0010959	regulation of metal ion transport	29/665	406/18722	0.000305795878164706	0.00325440152993274	CXCR4/TREM2/B2M/YWHAH/CALM1/FXYD5/LILRA5/TSPO/GLRX/HAMP/CLIC2/LGALS3/PTEN/FLNA/KCNE1/RHOA/EPB41/SARAF/AHNAK/WNK1/CALM3/KIF5B/C4orf3/KCNAB2/PTK2B/DIAPH1/CXCL12/PER1/PRNP	29
GO:0001701	in utero embryonic development	27/665	367/18722	0.000307278440510309	0.00325630532060921	VEGFA/CAPN2/KLF4/CEBPB/YBX3/ADM/ST14/SKIL/UBE2B/SCO2/TANC2/LY6E/JUNB/GRB2/CITED2/SOCS3/KLF2/GPI/YBX1/PHLDA2/COPS2/SF3B6/SMIM14/ACVRL1/CIR1/IGF2/SETD2	27
GO:0002292	T cell differentiation involved in immune response	10/665	75/18722	0.000308595534407834	0.00325630532060921	HLA-DRB1/HLA-DRA/GPR183/FGL2/ANXA1/NFKBIZ/CD86/NLRP3/SMAD7/RIPK2	10
GO:0034121	regulation of toll-like receptor signaling pathway	10/665	75/18722	0.000308595534407834	0.00325630532060921	TREM2/CD300A/RSAD2/CD36/IRF7/TNFAIP3/IFI35/GRAMD4/TLR2/WDFY1	10
GO:0048662	negative regulation of smooth muscle cell proliferation	10/665	75/18722	0.000308595534407834	0.00325630532060921	APOE/KLF4/SOD2/ANG/TNFAIP3/PTEN/HMOX1/RHOA/TRIB1/CDKN1A	10
GO:0048659	smooth muscle cell proliferation	17/665	184/18722	0.000312320857265375	0.00328863275552736	APOE/JUN/STAT1/KLF4/SOD2/ANG/NAMPT/MYD88/TNFAIP3/PTEN/HMOX1/RHOA/TRIB1/EGFR/PTAFR/CDKN1A/PHB	17
GO:2001236	regulation of extrinsic apoptotic signaling pathway	15/665	151/18722	0.000319785649740404	0.0033601156008664	IFI6/ATF3/SKIL/LGALS3/PYCARD/PEA15/TNFAIP3/MCL1/PTEN/HMOX1/LMNA/TNFSF12/G0S2/GPX1/NRP1	15
GO:0032731	positive regulation of interleukin-1 beta production	9/665	62/18722	0.00032122411679999	0.00336101865367569	CLEC7A/LILRA5/CD36/MYD88/PYCARD/EGR1/TYROBP/NLRP3/RIPK2	9
GO:1903078	positive regulation of protein localization to plasma membrane	9/665	62/18722	0.00032122411679999	0.00336101865367569	TREM2/LGALS3/EGFR/KIF5B/STX3/SQSTM1/EPHB2/ATP2C1/PRNP	9
GO:0031334	positive regulation of protein-containing complex assembly	20/665	237/18722	0.000322231656963173	0.00336447759476254	ISG15/VEGFA/CLEC7A/CD36/GSN/GMFG/ARPC4/MYD88/LGALS3/MSN/MAPRE1/PYCARD/GRB2/RAC1/RHOA/RHOC/PSMC6/PTK2B/TFRC/IQGAP2	20
GO:0002283	neutrophil activation involved in immune response	5/665	18/18722	0.000324626908579444	0.0033823809971485	MYD88/ITGAM/PTAFR/SPI1/TYROBP	5
GO:0070664	negative regulation of leukocyte proliferation	11/665	90/18722	0.000340102856856792	0.0035288333999546	FCGR2B/HLA-DRB1/IL4I1/GPNMB/CD300A/CEBPB/TNFAIP3/TNFRSF14/CD86/TYROBP/PRNP	11
GO:0099175	regulation of postsynapse organization	11/665	90/18722	0.000340102856856792	0.0035288333999546	FCGR2B/SRGN/APOE/IL1RAP/TANC2/PTEN/LRRK2/ABI3/CFL1/SIPA1L1/PRNP	11
GO:2000379	positive regulation of reactive oxygen species metabolic process	10/665	76/18722	0.000344244653676702	0.00356436651827751	CLEC7A/SOD2/TSPO/CD36/GRB2/ITGAM/EGFR/CDKN1A/PTK2B/TYROBP	10
GO:0062207	regulation of pattern recognition receptor signaling pathway	12/665	105/18722	0.000348813981492396	0.00360416941375718	TREM2/CD300A/RSAD2/CD36/IRF7/TNFAIP3/IFI35/DDX60/OASL/GRAMD4/TLR2/WDFY1	12
GO:1903050	regulation of proteolysis involved in cellular protein catabolic process	19/665	221/18722	0.000357062930567229	0.00368174847493595	NUPR1/TREM2/APOE/DAB2/SUMO2/PSME2/N4BP1/GABARAPL2/PTEN/TRIB1/RBX1/LRRK2/SDCBP/PSMC6/PLK3/PTK2B/CAMLG/SMAD7/GPX1	19
GO:0061136	regulation of proteasomal protein catabolic process	17/665	187/18722	0.000377425744285795	0.00385905939990028	NUPR1/TREM2/APOE/DAB2/SUMO2/PSME2/N4BP1/GABARAPL2/TRIB1/RBX1/LRRK2/SDCBP/PSMC6/PLK3/CAMLG/SMAD7/GPX1	17
GO:0050817	coagulation	19/665	222/18722	0.000377853126564437	0.00385905939990028	CD9/APOE/PLSCR1/MERTK/GNAQ/SERPING1/CD36/CLIC1/PDPN/FLNA/F13A1/PLAUR/MYL12A/PLAU/VKORC1/ANXA2/PIK3CB/EPHB2/FN1	19
GO:0002313	mature B cell differentiation involved in immune response	6/665	28/18722	0.000378917703652181	0.00385905939990028	FCGR2B/LGALS1/GPR183/IRF8/SPI1/PTK2B	6
GO:0031342	negative regulation of cell killing	6/665	28/18722	0.000378917703652181	0.00385905939990028	FCGR2B/HLA-A/HLA-B/HLA-F/IL7R/HLA-E	6
GO:0032607	interferon-alpha production	6/665	28/18722	0.000378917703652181	0.00385905939990028	STAT1/IFIH1/NMI/IRF7/SETD2/RIPK2	6
GO:0032647	regulation of interferon-alpha production	6/665	28/18722	0.000378917703652181	0.00385905939990028	STAT1/IFIH1/NMI/IRF7/SETD2/RIPK2	6
GO:2000249	regulation of actin cytoskeleton reorganization	7/665	39/18722	0.000394515997901712	0.00400970247356137	GMFG/HCLS1/ABI3/PTK2B/HAX1/IQGAP2/NRP1	7
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	8/665	51/18722	0.000400722310453074	0.00405814607870614	TREM2/STAT1/PYCARD/TNFAIP3/RHOA/TANK/CARD19/PER1	8
GO:0019730	antimicrobial humoral response	13/665	122/18722	0.000400915437554269	0.00405814607870614	SLC11A1/HLA-A/RNASE6/LYZ/CXCL8/ANG/GAPDH/CXCL2/CXCL3/HLA-E/PPBP/CCL13/RPL39	13
GO:0055076	transition metal ion homeostasis	14/665	138/18722	0.000404280297285223	0.0040838883689178	SLC11A1/B2M/SLC25A37/FTH1/HAMP/SCO2/MT1X/HMOX1/ATP6V1G1/FTL/S100A8/TFRC/FBXL5/PRNP	14
GO:0032507	maintenance of protein location in cell	9/665	64/18722	0.000409472144977818	0.00412794434186563	SRGN/HK2/TSPO/GSN/INSIG2/TMSB10/TXN/ARL2BP/VPS13A	9
GO:0090150	establishment of protein localization to membrane	21/665	260/18722	0.000416409063701468	0.0041893786368346	CALM1/NCF1/RAB8A/VAMP5/SEC61G/ZDHHC20/GOLGA7/ITGAM/KCNE1/EGFR/KRT18/SDCBP/CALM3/TIMM8B/STX3/ATG3/CAMLG/TIMM10/RAB31/ATP2C1/PRNP	21
GO:0034614	cellular response to reactive oxygen species	15/665	155/18722	0.000423616141348598	0.00425195958579259	JUN/KLF4/SOD2/NCF1/CD36/BNIP3/TNFAIP3/FOS/ANXA1/KLF2/RHOB/EGFR/LRRK2/TXN/CYP1B1	15
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	10/665	78/18722	0.000425891215360523	0.00425195958579259	VEGFA/KLF4/IFI6/CARD16/CD44/GPI/LAMTOR5/PLAUR/NR4A1/GPX1	10
GO:0039530	MDA-5 signaling pathway	4/665	11/18722	0.00042638053185232	0.00425195958579259	OAS3/IFIH1/IRF7/DDX60	4
GO:0002281	macrophage activation involved in immune response	5/665	19/18722	0.000427762533781951	0.00425195958579259	TREM2/NMI/IFI35/GRN/TYROBP	5
GO:0002888	positive regulation of myeloid leukocyte mediated immunity	5/665	19/18722	0.000427762533781951	0.00425195958579259	ITGAM/PTAFR/SPI1/HLA-E/TYROBP	5
GO:0046782	regulation of viral transcription	5/665	19/18722	0.000427762533781951	0.00425195958579259	IFITM3/ZFP36/LARP7/MDFIC/RSF1	5
GO:0001667	ameboidal-type cell migration	32/665	475/18722	0.000429356820746965	0.00425928822178127	VEGFA/APOE/CTSH/TIMP1/KLF4/GLUL/CSNK2B/SMURF2/PTEN/PRKX/HMOX1/RAC1/ANXA1/RHOA/GPI/RHOB/GLIPR2/TNFSF12/PLEC/GRN/MAP3K3/ACVRL1/RAB13/PTK2B/CAP1/PIK3CB/FN1/CYP1B1/RIN2/NR4A1/GPX1/NRP1	32
GO:0031647	regulation of protein stability	23/665	298/18722	0.000431663772771539	0.00427364332803695	CTSH/GNAQ/GSN/UBE2B/GAPDH/PYCARD/RASSF2/PTEN/GOLGA7/FLNA/LMNA/PTGES3/LRRK2/GRN/CTSA/RNF5/TYROBP/IFI30/PHB/CAMLG/CD81/SMAD7/PRNP	23
GO:0034446	substrate adhesion-dependent cell spreading	12/665	108/18722	0.000452602553144827	0.00446504965689859	LIMS1/S100A10/MERTK/MYADM/RAC1/GBP1/PARVB/PDPN/FLNA/RHOA/FN1/NRP1	12
GO:0106027	neuron projection organization	11/665	93/18722	0.000452793768023519	0.00446504965689859	FCGR2B/TREM2/APOE/TANC2/PTEN/LRRK2/ABI3/EPHB2/CFL1/SIPA1L1/PRNP	11
GO:0030041	actin filament polymerization	17/665	190/18722	0.000453944201344106	0.00446753006075289	CAPG/MYADM/GSN/ANG/GMFG/ARPC4/PYCARD/GRB2/RAC1/RHOA/HCLS1/COTL1/TMSB10/PTK2B/DIAPH1/HAX1/IQGAP2	17
GO:0045453	bone resorption	9/665	65/18722	0.000460557574987249	0.00452365839463761	ADAM8/ACP5/SNX10/HAMP/TNFAIP3/RAC1/EGFR/PTK2B/TFRC	9
GO:0010863	positive regulation of phospholipase C activity	7/665	40/18722	0.000463726776764352	0.00454580292015549	C5AR1/GNAQ/ANG/EGFR/PTAFR/CD86/PHB	7
GO:0071241	cellular response to inorganic substance	19/665	226/18722	0.00047189827378009	0.00461680004072253	JUND/B2M/JUN/FBP1/NCF1/TSPO/FOSB/MT1X/BNIP3/JUNB/HMOX1/ALOX5AP/FOS/EGFR/LRRK2/WNK1/CACYBP/HSD17B1/PRNP	19
GO:0030183	B cell differentiation	14/665	141/18722	0.000503193111243604	0.00491330012353774	FCGR2B/IL4I1/LGALS1/GPR183/ZFP36L2/TNFSF13B/KLF6/IRF2BP2/IRF8/MMP14/TPD52/SPI1/PTK2B/CMTM7	14
GO:0071621	granulocyte chemotaxis	13/665	125/18722	0.000507344879964905	0.00493595980762779	CD74/JAML/CXCL8/C5AR1/LGALS3/TREM1/RAC1/ANXA1/CXCL2/S100A8/CXCL3/PPBP/CCL13	13
GO:0050878	regulation of body fluid levels	27/665	379/18722	0.000507500092896942	0.00493595980762779	OAS2/VEGFA/CD9/APOE/HK2/PLSCR1/MERTK/ADM/GNAQ/SERPING1/CD36/CLIC1/PDPN/FLNA/GPI/F13A1/EGFR/PLEC/WNK1/PLAUR/MYL12A/PLAU/VKORC1/ANXA2/PIK3CB/EPHB2/FN1	27
GO:0042093	T-helper cell differentiation	9/665	66/18722	0.000516764570963536	0.00498702896638597	HLA-DRB1/HLA-DRA/GPR183/ANXA1/NFKBIZ/CD86/NLRP3/SMAD7/RIPK2	9
GO:0050766	positive regulation of phagocytosis	9/665	66/18722	0.000516764570963536	0.00498702896638597	FCGR2B/SLC11A1/TREM2/CLEC7A/MERTK/CD36/RAP1A/PYCARD/RAB31	9
GO:0051893	regulation of focal adhesion assembly	9/665	66/18722	0.000516764570963536	0.00498702896638597	VEGFA/LIMS1/S100A10/PTEN/RAC1/RHOA/MMP14/ACVRL1/NRP1	9
GO:0090109	regulation of cell-substrate junction assembly	9/665	66/18722	0.000516764570963536	0.00498702896638597	VEGFA/LIMS1/S100A10/PTEN/RAC1/RHOA/MMP14/ACVRL1/NRP1	9
GO:0048145	regulation of fibroblast proliferation	10/665	80/18722	0.00052301892215117	0.00502850245424222	NUPR1/CD300A/CD74/S100A6/FTH1/MIF/CDKN1A/ANXA2/FN1/IFI30	10
GO:0034381	plasma lipoprotein particle clearance	8/665	53/18722	0.000524097438892851	0.00502850245424222	TREM2/APOE/APOC1/CD36/MSR1/HMOX1/SOAT1/ANXA2	8
GO:0043620	regulation of DNA-templated transcription in response to stress	8/665	53/18722	0.000524097438892851	0.00502850245424222	VEGFA/JUN/CEBPB/ATF3/CITED2/HMOX1/KLF2/EGR1	8
GO:0032733	positive regulation of interleukin-10 production	7/665	41/18722	0.000542283366512283	0.00518297756070394	ISG15/TREM2/CLEC7A/LILRA5/PYCARD/CD83/TLR2	7
GO:1905521	regulation of macrophage migration	7/665	41/18722	0.000542283366512283	0.00518297756070394	TREM2/CD9/C5AR1/MIF/MMP14/PTK2B/CD81	7
GO:0002532	production of molecular mediator involved in inflammatory response	11/665	95/18722	0.000544076293337827	0.00519013277905758	TREM2/ALOX5/CLEC7A/NCF1/CD36/MYD88/PYCARD/ALOX5AP/GRN/PER1/PLD3	11
GO:0032874	positive regulation of stress-activated MAPK cascade	13/665	126/18722	0.000547752539978439	0.00520291320458499	FCGR2B/VEGFA/EIF2AK2/CLEC7A/NCF1/MYD88/PYCARD/RASSF2/SDCBP/MAP3K3/SPI1/PTK2B/RIPK2	13
GO:0003159	morphogenesis of an endothelium	5/665	20/18722	0.000553790962822024	0.00520291320458499	CXCR4/CSNK2B/RHOA/RHOB/ACVRL1	5
GO:0032495	response to muramyl dipeptide	5/665	20/18722	0.000553790962822024	0.00520291320458499	VIM/NFKBIA/TNFAIP3/CHMP5/RIPK2	5
GO:0061154	endothelial tube morphogenesis	5/665	20/18722	0.000553790962822024	0.00520291320458499	CXCR4/CSNK2B/RHOA/RHOB/ACVRL1	5
GO:0071243	cellular response to arsenic-containing substance	5/665	20/18722	0.000553790962822024	0.00520291320458499	ATF3/SLC38A2/HMOX1/HNRNPA1/CPEB2	5
GO:0072567	chemokine (C-X-C motif) ligand 2 production	5/665	20/18722	0.000553790962822024	0.00520291320458499	CD74/OAS1/OAS3/KLF4/MYD88	5
GO:0098543	detection of other organism	5/665	20/18722	0.000553790962822024	0.00520291320458499	HLA-DRB1/HLA-A/HLA-B/CLEC7A/TLR2	5
GO:2000341	regulation of chemokine (C-X-C motif) ligand 2 production	5/665	20/18722	0.000553790962822024	0.00520291320458499	CD74/OAS1/OAS3/KLF4/MYD88	5
GO:0050728	negative regulation of inflammatory response	16/665	176/18722	0.000554932340986909	0.00520379949944328	FCGR2B/HLA-DRB1/TREM2/APOE/ALOX5/KLF4/ACP5/ZFP36/HAMP/TNFAIP3/SOCS3/GRN/SIGLEC10/RB1/NLRP3/GPX1	16
GO:0007202	activation of phospholipase C activity	6/665	30/18722	0.000562210804358856	0.0052522325144051	C5AR1/GNAQ/ANG/EGFR/CD86/PHB	6
GO:1903579	negative regulation of ATP metabolic process	6/665	30/18722	0.000562210804358856	0.0052522325144051	NUPR1/DDIT4/FBP1/TSPO/DNAJC15/RHOA	6
GO:0048144	fibroblast proliferation	10/665	81/18722	0.000578063588749643	0.00537387283501206	NUPR1/CD300A/CD74/S100A6/FTH1/MIF/CDKN1A/ANXA2/FN1/IFI30	10
GO:0010517	regulation of phospholipase activity	9/665	67/18722	0.000578475244815182	0.00537387283501206	C5AR1/GNAQ/ANG/ANXA1/RGS2/EGFR/PTAFR/CD86/PHB	9
GO:0035914	skeletal muscle cell differentiation	9/665	67/18722	0.000578475244815182	0.00537387283501206	NUPR1/SAP30/ATF3/CITED2/FOS/EGR1/COPS2/RB1/NR4A1	9
GO:0022411	cellular component disassembly	30/665	443/18722	0.000589795419786569	0.00546539538167222	TREM2/CAPG/DDIT4/ADAM8/HK2/CALM1/BNIP3L/TSPO/GSN/C1QB/MAP1LC3B/BNIP3/C1QC/GABARAPL2/CISD2/MMP19/PDPN/ITGAM/WDR45B/PLK3/MMP14/KIF5B/SQSTM1/ATG3/WIPI2/HAX1/VTA1/CFL1/CHMP5/C1QA	30
GO:0031589	cell-substrate adhesion	26/665	363/18722	0.000590526623734	0.00546539538167222	LGALS1/VEGFA/LIMS1/MYO1G/S100A10/MERTK/MYADM/CD44/CD36/LYVE1/PTEN/PRKX/RAC1/GBP1/PARVB/PDPN/FLNA/RHOA/MMP14/PLAU/ACVRL1/PTK2B/PIK3CB/FN1/RIN2/NRP1	26
GO:0070228	regulation of lymphocyte apoptotic process	8/665	54/18722	0.000596396229135194	0.00550945958885114	TSC22D3/CD74/ADAM8/IRS2/LGALS3/PTEN/IL7R/DOCK8	8
GO:0030336	negative regulation of cell migration	25/665	344/18722	0.000605514389057364	0.00558331449650296	IFITM1/APOE/CD300A/DUSP1/CD74/TIMP1/ADORA3/KLF4/CSNK2B/TMIGD3/MIF/BST2/RIN3/CITED2/PTEN/HMOX1/RAC1/RHOA/RHOB/TRIB1/IL27RA/ACVRL1/CYP1B1/CXCL12/SMAD7	25
GO:0002424	T cell mediated immune response to tumor cell	4/665	12/18722	0.000621652933086276	0.00570039682184278	HLA-DRB1/IL4I1/HLA-A/AHR	4
GO:0043471	regulation of cellular carbohydrate catabolic process	4/665	12/18722	0.000621652933086276	0.00570039682184278	PPP1CB/PPP1R3B/PGAM1/SCARB2	4
GO:0140052	cellular response to oxidised low-density lipoprotein particle stimulus	4/665	12/18722	0.000621652933086276	0.00570039682184278	TREM2/CD36/MYD88/CD68	4
GO:0002526	acute inflammatory response	12/665	112/18722	0.000630481214530548	0.00574431383044342	FCGR2B/NUPR1/ADAM8/PLSCR1/CEBPB/HAMP/TREM1/ALOX5AP/S100A8/HLA-E/FN1/NLRP3	12
GO:0046632	alpha-beta T cell differentiation	12/665	112/18722	0.000630481214530548	0.00574431383044342	HLA-DRB1/HLA-DRA/GPR183/RSAD2/ANXA1/RHOA/NFKBIZ/CD83/CD86/NLRP3/SMAD7/RIPK2	12
GO:0032691	negative regulation of interleukin-1 beta production	7/665	42/18722	0.000631065463062798	0.00574431383044342	TREM2/ACP5/ERRFI1/CARD16/TNFAIP3/SERPINB1/NLRP3	7
GO:1900274	regulation of phospholipase C activity	7/665	42/18722	0.000631065463062798	0.00574431383044342	C5AR1/GNAQ/ANG/EGFR/PTAFR/CD86/PHB	7
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	13/665	128/18722	0.000636771144569525	0.00577400779974897	FCGR2B/VEGFA/EIF2AK2/CLEC7A/NCF1/MYD88/PYCARD/RASSF2/SDCBP/MAP3K3/SPI1/PTK2B/RIPK2	13
GO:0001892	embryonic placenta development	10/665	82/18722	0.000637812934016536	0.00577400779974897	CEBPB/ADM/ST14/JUNB/GRB2/CITED2/SOCS3/PHLDA2/IGF2/SETD2	10
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	10/665	82/18722	0.000637812934016536	0.00577400779974897	ATF3/SKIL/LGALS3/PEA15/TNFAIP3/PTEN/HMOX1/BLOC1S2/SPI1/GPX1	10
GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	9/665	68/18722	0.000646089178508551	0.00583829675852273	HLA-DRB1/HLA-DRA/GPR183/ANXA1/NFKBIZ/CD86/NLRP3/SMAD7/RIPK2	9
GO:0043393	regulation of protein binding	17/665	196/18722	0.000647792749724935	0.00584306708917047	IFIT1/IFIT2/B2M/APOE/DAB2/CARD16/MAPRE1/DTX3L/PPP2CB/EPB41/LRRK2/PHLDA2/CDKN1A/CAMK1/ANXA2/RIPK2/NRP1	17
GO:0038066	p38MAPK cascade	8/665	55/18722	0.000676539482121259	0.00608029154817841	TREM2/VEGFA/DUSP1/NCF1/ZFP36/MAP3K3/SPI1/PER1	8
GO:1905517	macrophage migration	8/665	55/18722	0.000676539482121259	0.00608029154817841	TREM2/CD9/C5AR1/MIF/LGALS3/MMP14/PTK2B/CD81	8
GO:0034101	erythrocyte homeostasis	13/665	129/18722	0.000685668332026136	0.00614012902733315	ISG15/VEGFA/B2M/STAT1/ZFP36/MAFB/CITED2/HMOX1/KLF2/HCLS1/GPI/SPI1/RB1	13
GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	13/665	129/18722	0.000685668332026136	0.00614012902733315	CTSH/EGLN3/CLEC7A/RPS27L/GSN/PYCARD/FAM162A/RHOA/CTSD/CYCS/S100A8/GRAMD4/NLRP3	13
GO:0051271	negative regulation of cellular component movement	26/665	367/18722	0.000694713207631018	0.00620993640634202	IFITM1/CD9/APOE/CD300A/DUSP1/CD74/TIMP1/ADORA3/KLF4/CSNK2B/TMIGD3/MIF/BST2/RIN3/CITED2/PTEN/HMOX1/RAC1/RHOA/RHOB/TRIB1/IL27RA/ACVRL1/CYP1B1/CXCL12/SMAD7	26
GO:0050672	negative regulation of lymphocyte proliferation	10/665	83/18722	0.000702570225685107	0.00624139158248823	FCGR2B/HLA-DRB1/IL4I1/GPNMB/CD300A/CEBPB/TNFRSF14/CD86/TYROBP/PRNP	10
GO:0009117	nucleotide metabolic process	32/665	489/18722	0.000703711039448604	0.00624139158248823	NUPR1/LDHA/TREM2/DDIT4/NT5C3A/HK2/TYMP/PGK1/FBP1/ALDOA/PKM/ACSL1/HSD17B4/UPP1/TPI1/PAPSS1/NAMPT/CMPK1/GAPDH/ENO1/PARP9/RRM2B/RHOA/PAPSS2/GPI/LRRK2/ENO2/PGAM1/GUK1/ABHD14B/KMO/GALK1	32
GO:0046597	negative regulation of viral entry into host cell	5/665	21/18722	0.000705767015967482	0.00624139158248823	IFITM1/IFITM3/IFITM2/GSN/LY6E	5
GO:0046641	positive regulation of alpha-beta T cell proliferation	5/665	21/18722	0.000705767015967482	0.00624139158248823	HLA-A/HLA-E/EBI3/CD81/RIPK2	5
GO:0150146	cell junction disassembly	5/665	21/18722	0.000705767015967482	0.00624139158248823	TREM2/C1QB/C1QC/ITGAM/C1QA	5
GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	5/665	21/18722	0.000705767015967482	0.00624139158248823	CD74/MIF/CD44/RRM2B/ZNF385A	5
GO:0002287	alpha-beta T cell activation involved in immune response	9/665	69/18722	0.000720023508362472	0.00634488800808774	HLA-DRB1/HLA-DRA/GPR183/ANXA1/NFKBIZ/CD86/NLRP3/SMAD7/RIPK2	9
GO:0002293	alpha-beta T cell differentiation involved in immune response	9/665	69/18722	0.000720023508362472	0.00634488800808774	HLA-DRB1/HLA-DRA/GPR183/ANXA1/NFKBIZ/CD86/NLRP3/SMAD7/RIPK2	9
GO:0001503	ossification	28/665	408/18722	0.000723213564919872	0.00636171932327746	ISG15/SRGN/JUND/IFITM1/GPNMB/VCAN/ALOX5/CEBPB/SNX10/HSD17B4/ECM1/OSTF1/KLF10/JUNB/CLIC1/RASSF2/HIF1A-AS2/RHOA/DHRS3/EGFR/FBN2/MMP14/FBXL15/PTK2B/IGF2/TOB1/PHB/SMAD7	28
GO:0002377	immunoglobulin production	18/665	216/18722	0.000729932346994522	0.00640749596109716	FCGR2B/HLA-DQA1/HLA-DRB1/HLA-DQB1/HLA-DRA/HLA-DPB1/HLA-DPA1/B2M/HLA-DOA/HLA-DMA/GPI/IL27RA/CD86/HLA-E/TFRC/EPHB2/PHB/HLA-DMB	18
GO:0014002	astrocyte development	7/665	43/18722	0.000730996018097	0.00640749596109716	VIM/TREM2/C5AR1/EGFR/GRN/S100A8/C1QA	7
GO:0009743	response to carbohydrate	20/665	253/18722	0.000741538253664919	0.0064770564511681	HLA-DRB1/LDHA/TREM2/LGALS1/TXNIP/SLC2A5/GLUL/CLEC7A/SOD2/DYNLL1/IRS2/RAP1A/NAMPT/PTEN/RAC1/RHOA/EGR1/KRT18/KIF5B/PTK2B	20
GO:0097305	response to alcohol	20/665	253/18722	0.000741538253664919	0.0064770564511681	CALM1/KLF4/SOD2/AHR/TSPO/HAMP/FOSB/PTEN/FOS/EIF4EBP1/KLF2/RHOA/RGS2/CALM3/S100A8/SPI1/CDKN1A/PTK2B/KLF9/NLRP3	20
GO:0002886	regulation of myeloid leukocyte mediated immunity	8/665	56/18722	0.000765138233979873	0.00664814164839155	FCGR2B/CD300A/HMOX1/ITGAM/PTAFR/SPI1/HLA-E/TYROBP	8
GO:0043388	positive regulation of DNA binding	8/665	56/18722	0.000765138233979873	0.00664814164839155	CALM1/KLF4/LAMTOR5/PLAUR/CALM3/EDF1/TXN/RB1	8
GO:0071385	cellular response to glucocorticoid stimulus	8/665	56/18722	0.000765138233979873	0.00664814164839155	DDIT4/ZFP36L2/ERRFI1/ZFP36/ANXA1/EGFR/KLF9/EIF4E	8
GO:0032945	negative regulation of mononuclear cell proliferation	10/665	84/18722	0.000772650974760722	0.00670170217200836	FCGR2B/HLA-DRB1/IL4I1/GPNMB/CD300A/CEBPB/TNFRSF14/CD86/TYROBP/PRNP	10
GO:0071214	cellular response to abiotic stimulus	24/665	331/18722	0.000797388524556155	0.00689221037746799	TIMP1/CRIP1/YBX3/ERRFI1/CARD16/TSPO/HAMP/SLC38A2/NAMPT/MYD88/BNIP3/N4BP1/GRB2/PTEN/RAC1/EGR1/RHOB/EGFR/PLEC/PTAFR/MAP3K2/TANK/CDKN1A/XPC	24
GO:0104004	cellular response to environmental stimulus	24/665	331/18722	0.000797388524556155	0.00689221037746799	TIMP1/CRIP1/YBX3/ERRFI1/CARD16/TSPO/HAMP/SLC38A2/NAMPT/MYD88/BNIP3/N4BP1/GRB2/PTEN/RAC1/EGR1/RHOB/EGFR/PLEC/PTAFR/MAP3K2/TANK/CDKN1A/XPC	24
GO:0045861	negative regulation of proteolysis	25/665	351/18722	0.000809188889715801	0.00698206385744363	VEGFA/TIMP1/KLF4/IFI6/CARD16/ECM1/SERPING1/CD44/BST2/GAPDH/N4BP1/GABARAPL2/CSTB/GPI/LAMTOR5/LRRK2/SDCBP/PLAUR/ANXA2/CAMLG/NR4A1/TMEM59/SERPINB1/PRNP/GPX1	25
GO:0040013	negative regulation of locomotion	27/665	391/18722	0.000814419628762207	0.00701022920281971	IFITM1/APOE/CD300A/DUSP1/CD74/TIMP1/ADORA3/KLF4/CSNK2B/TMIGD3/MIF/BST2/RIN3/CITED2/PTEN/HMOX1/RAC1/RHOA/RHOB/TRIB1/ARRDC3/IL27RA/ACVRL1/CYP1B1/CXCL12/SMAD7/NRP1	27
GO:0014074	response to purine-containing compound	14/665	148/18722	0.000816684649584027	0.00701022920281971	LDHA/DUSP1/JUN/STAT1/AHR/FOSB/RAP1A/PTEN/RAPGEF1/FOS/KCNE1/PTAFR/PTK2B/PER1	14
GO:2001056	positive regulation of cysteine-type endopeptidase activity	14/665	148/18722	0.000816684649584027	0.00701022920281971	CTSH/EGLN3/CLEC7A/RPS27L/GSN/PYCARD/FAM162A/RHOA/CTSD/CYCS/S100A8/GRAMD4/NLRP3/RIPK2	14
GO:0050999	regulation of nitric-oxide synthase activity	7/665	44/18722	0.000843040454308311	0.00722398458260742	APOE/CALM1/DDAH2/EGFR/CALM3/PTK2B/PIK3CB	7
GO:0010507	negative regulation of autophagy	10/665	85/18722	0.000848383004157762	0.00723235597026429	NUPR1/TREM2/TSPO/NAMPT/MCL1/HMOX1/LRRK2/TAB2/CTSA/RNF5	10
GO:0032092	positive regulation of protein binding	10/665	85/18722	0.000848383004157762	0.00723235597026429	B2M/APOE/MAPRE1/DTX3L/PPP2CB/EPB41/LRRK2/ANXA2/RIPK2/NRP1	10
GO:0055072	iron ion homeostasis	10/665	85/18722	0.000848383004157762	0.00723235597026429	SLC11A1/B2M/SLC25A37/FTH1/HAMP/HMOX1/ATP6V1G1/FTL/TFRC/FBXL5	10
GO:0002011	morphogenesis of an epithelial sheet	8/665	57/18722	0.000862829983515115	0.00732429596797092	CD44/PTEN/PDPN/FLNA/RHOA/RHOC/LIN7C/ACVRL1	8
GO:1900024	regulation of substrate adhesion-dependent cell spreading	8/665	57/18722	0.000862829983515115	0.00732429596797092	LIMS1/S100A10/MYADM/RAC1/GBP1/PDPN/FLNA/NRP1	8
GO:0021782	glial cell development	12/665	116/18722	0.000863589021575646	0.00732429596797092	VIM/TREM2/CD9/NDRG1/C5AR1/PTEN/EGFR/PLEC/GRN/S100A8/TLR2/C1QA	12
GO:0043112	receptor metabolic process	15/665	166/18722	0.000869225684236141	0.00733994021932064	VEGFA/CD9/APOE/CXCL8/ADM/CD36/RIN3/GRB2/DTX3L/SDCBP/ANXA2/TFRC/RAB31/CHMP5/CD81	15
GO:0051592	response to calcium ion	14/665	149/18722	0.000872687322999627	0.00733994021932064	JUND/DUSP1/TXNIP/CALM1/FOSB/JUNB/ALOX5AP/FOS/EGFR/WNK1/CALM3/CACYBP/PTK2B/KCNMA1	14
GO:0032494	response to peptidoglycan	4/665	13/18722	0.000872817840969517	0.00733994021932064	TREM2/C5AR1/MYD88/RIPK2	4
GO:0060670	branching involved in labyrinthine layer morphogenesis	4/665	13/18722	0.000872817840969517	0.00733994021932064	ADM/ST14/GRB2/SOCS3	4
GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	4/665	13/18722	0.000872817840969517	0.00733994021932064	ATF3/SKIL/PEA15/PTEN	4
GO:0032727	positive regulation of interferon-alpha production	5/665	22/18722	0.000886876549181309	0.00741005243699197	STAT1/IFIH1/IRF7/SETD2/RIPK2	5
GO:0045624	positive regulation of T-helper cell differentiation	5/665	22/18722	0.000886876549181309	0.00741005243699197	ANXA1/NFKBIZ/CD86/NLRP3/RIPK2	5
GO:0051412	response to corticosterone	5/665	22/18722	0.000886876549181309	0.00741005243699197	CALM1/FOSB/FOS/CALM3/CDKN1A	5
GO:0061515	myeloid cell development	9/665	71/18722	0.000888609909949138	0.00741005243699197	EVI2B/PIP4K2A/ABI1/CITED2/KLF2/ANXA2/TYROBP/ZNF385A/TLR2	9
GO:0150116	regulation of cell-substrate junction organization	9/665	71/18722	0.000888609909949138	0.00741005243699197	VEGFA/LIMS1/S100A10/PTEN/RAC1/RHOA/MMP14/ACVRL1/NRP1	9
GO:0001558	regulation of cell growth	28/665	414/18722	0.000904338908021096	0.00752042252112522	CXCR4/VEGFA/APOE/BTG1/SGK1/FBP1/DPYSL2/BST2/CXCL16/HAMP/ENO1/OGFR/RHOA/RGS2/EGFR/SDCBP/S100A8/MMP14/CDKN1A/ACVRL1/PTK2B/RB1/FN1/CCDC85B/PHB/CXCL12/SMAD7/NRP1	28
GO:1903829	positive regulation of cellular protein localization	21/665	276/18722	0.000904871764111244	0.00752042252112522	TREM2/LGALS3/MSN/DTX3L/PARP9/ITGAM/FLNA/HCLS1/LAMTOR5/EGFR/EPB41/LARP7/KIF5B/STX3/SQSTM1/TYROBP/TFRC/EPHB2/CD81/ATP2C1/PRNP	21
GO:0006753	nucleoside phosphate metabolic process	32/665	497/18722	0.000921636238173156	0.00764696511472552	NUPR1/LDHA/TREM2/DDIT4/NT5C3A/HK2/TYMP/PGK1/FBP1/ALDOA/PKM/ACSL1/HSD17B4/UPP1/TPI1/PAPSS1/NAMPT/CMPK1/GAPDH/ENO1/PARP9/RRM2B/RHOA/PAPSS2/GPI/LRRK2/ENO2/PGAM1/GUK1/ABHD14B/KMO/GALK1	32
GO:2000117	negative regulation of cysteine-type endopeptidase activity	10/665	86/18722	0.000930106496314341	0.00770438214447046	VEGFA/KLF4/IFI6/CARD16/CD44/GPI/LAMTOR5/PLAUR/NR4A1/GPX1	10
GO:0009314	response to radiation	30/665	456/18722	0.000938357820909961	0.00775979762050334	JUND/DUSP1/JUN/TIMP1/CRIP1/SLC1A3/CARD16/GNAQ/SOD2/BHLHE40/HAMP/UBE2B/NAMPT/N4BP1/PPP1CB/GRB2/FOS/ANXA1/EGR1/RHOB/EGFR/TANK/PLK3/CDKN1A/TXN/DYNLRB1/CXCL12/PER1/XPC/GPX1	30
GO:0044088	regulation of vacuole organization	7/665	45/18722	0.000968205710059835	0.0079839137457487	NUPR1/PIP4K2A/LRRK2/GRN/RNF5/ANXA2/SCARB2	7
GO:0001954	positive regulation of cell-matrix adhesion	8/665	58/18722	0.000970278451193605	0.0079839137457487	VEGFA/LIMS1/S100A10/CD36/RAC1/PTK2B/RIN2/NRP1	8
GO:0043525	positive regulation of neuron apoptotic process	8/665	58/18722	0.000970278451193605	0.0079839137457487	NUPR1/JUN/MCL1/ITGAM/RHOA/GRN/TYROBP/PRNP	8
GO:0061041	regulation of wound healing	13/665	134/18722	0.000980219758035128	0.00805238379741254	CXCR4/CD9/APOE/ALOX5/CLEC7A/SERPING1/CD36/TNFAIP3/PTEN/ANXA1/PLAU/ANXA2/EPHB2	13
GO:0099173	postsynapse organization	15/665	168/18722	0.000982727177478306	0.00805966018492934	FCGR2B/SRGN/TREM2/APOE/NDRG1/IL1RAP/TANC2/PTEN/LRRK2/ABI3/EPHB2/CFL1/SIPA1L1/PRNP/NRP1	15
GO:0048041	focal adhesion assembly	10/665	87/18722	0.00101817401935466	0.00833661429356286	VEGFA/LIMS1/S100A10/PTEN/RAC1/RHOA/MMP14/ACVRL1/PTK2B/NRP1	10
GO:0032732	positive regulation of interleukin-1 production	9/665	73/18722	0.00108792339288399	0.00889305799775236	CLEC7A/LILRA5/CD36/MYD88/PYCARD/EGR1/TYROBP/NLRP3/RIPK2	9
GO:0043300	regulation of leukocyte degranulation	7/665	46/18722	0.00110753911952191	0.00903853764207533	FCGR2B/CD300A/HLA-F/HMOX1/ITGAM/PTAFR/SPI1	7
GO:2000146	negative regulation of cell motility	25/665	359/18722	0.00111267786695334	0.00905296913451257	IFITM1/APOE/CD300A/DUSP1/CD74/TIMP1/ADORA3/KLF4/CSNK2B/TMIGD3/MIF/BST2/RIN3/CITED2/PTEN/HMOX1/RAC1/RHOA/RHOB/TRIB1/IL27RA/ACVRL1/CYP1B1/CXCL12/SMAD7	25
GO:0070098	chemokine-mediated signaling pathway	10/665	88/18722	0.00111295053142599	0.00905296913451257	CXCR4/TREM2/CXCL8/WNK1/CXCL2/CXCL3/PTK2B/PPBP/CCL13/CXCL12	10
GO:1900180	regulation of protein localization to nucleus	13/665	136/18722	0.00112453651069438	0.00913226545449522	GLUL/CD36/NUP58/DTX3L/PARP9/FLNA/HCLS1/LMNA/LAMTOR5/LARP7/TFRC/MDFIC/SUMO3	13
GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	6/665	34/18722	0.00112883424353157	0.00913730649894449	OAS3/IFIH1/IRF7/DDX60/OASL/PHB	6
GO:1990000	amyloid fibril formation	6/665	34/18722	0.00112883424353157	0.00913730649894449	TREM2/B2M/APOE/CD36/GSN/PFDN6	6
GO:0071901	negative regulation of protein serine/threonine kinase activity	12/665	120/18722	0.00116452750246976	0.00941089705247922	APOE/CD300A/DUSP1/PYCARD/TNFAIP3/PTEN/RGS2/AIDA/CDKN1A/RB1/PIK3CB/CDKN1C	12
GO:0034284	response to monosaccharide	18/665	225/18722	0.00116805883192782	0.0094241110303267	HLA-DRB1/LDHA/TREM2/LGALS1/TXNIP/SLC2A5/GLUL/SOD2/DYNLL1/IRS2/NAMPT/PTEN/RAC1/RHOA/EGR1/KRT18/KIF5B/PTK2B	18
GO:0001771	immunological synapse formation	4/665	14/18722	0.00118779627566511	0.0095369103231916	LGALS3/MSN/DOCK8/CD81	4
GO:0042921	glucocorticoid receptor signaling pathway	4/665	14/18722	0.00118779627566511	0.0095369103231916	YWHAH/PTGES3/PHB/PER1	4
GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	4/665	14/18722	0.00118779627566511	0.0095369103231916	CD74/MIF/CD44/ZNF385A	4
GO:1902903	regulation of supramolecular fiber organization	26/665	382/18722	0.00124171069915778	0.00995371318518413	TREM2/CAPG/APOE/S100A10/MYADM/GSN/GMFG/ARPC4/MAPRE1/PYCARD/GRB2/RAC1/FLNA/RHOA/HCLS1/COTL1/RHOC/TMSB10/PTK2B/RB1/HAX1/PFDN6/IQGAP2/CXCL12/GPX1/NRP1	26
GO:0042311	vasodilation	7/665	47/18722	0.00126212713501991	0.0100686546726307	APOE/SOD2/KLF2/RGS2/EGFR/KCNMA1/GPX1	7
GO:0097028	dendritic cell differentiation	7/665	47/18722	0.00126212713501991	0.0100686546726307	FCGR2B/TREM2/AZI2/HLA-B/CEBPB/IRF8/SPI1	7
GO:1900744	regulation of p38MAPK cascade	7/665	47/18722	0.00126212713501991	0.0100686546726307	TREM2/VEGFA/DUSP1/NCF1/MAP3K3/SPI1/PER1	7
GO:0060537	muscle tissue development	27/665	403/18722	0.00127223916202517	0.0101330587103607	NUPR1/SAP30/VEGFA/YBX3/ATF3/VAMP5/HAMP/LY6E/CITED2/PTEN/FOS/RHOA/EGR1/RGS2/LMNA/PLEC/GPCPD1/COPS2/CACYBP/IGF2/RB1/NR4A1/JARID2/TIPARP/SMAD7/MYL6/GPX1	27
GO:0030522	intracellular receptor signaling pathway	20/665	265/18722	0.00130897475418082	0.0104089672452458	YWHAH/NFKBIA/DAB2/OAS3/IFIH1/NR4A2/AHR/IRF7/TNFAIP3/CITED2/KLF2/RHOA/DHRS3/PTGES3/DDX60/OASL/PHB/NR4A1/PER1/RIPK2	20
GO:1902905	positive regulation of supramolecular fiber organization	17/665	209/18722	0.00132150862987411	0.0104625208594829	APOE/S100A10/GSN/GMFG/ARPC4/MAPRE1/PYCARD/GRB2/RAC1/FLNA/RHOA/RHOC/PTK2B/RB1/IQGAP2/GPX1/NRP1	17
GO:0034405	response to fluid shear stress	6/665	35/18722	0.00132202476856242	0.0104625208594829	KLF4/CITED2/KLF2/PLEC/PTK2B/SMAD7	6
GO:0046640	regulation of alpha-beta T cell proliferation	6/665	35/18722	0.00132202476856242	0.0104625208594829	HLA-A/TNFRSF14/HLA-E/EBI3/CD81/RIPK2	6
GO:0046849	bone remodeling	10/665	90/18722	0.00132415217615038	0.0104626968449402	ADAM8/ACP5/SNX10/HAMP/TNFAIP3/RASSF2/RAC1/EGFR/PTK2B/TFRC	10
GO:0014706	striated muscle tissue development	26/665	384/18722	0.00133729325039726	0.010549757864245	NUPR1/SAP30/VEGFA/YBX3/ATF3/VAMP5/HAMP/LY6E/CITED2/PTEN/FOS/RHOA/EGR1/RGS2/LMNA/PLEC/GPCPD1/COPS2/CACYBP/IGF2/RB1/NR4A1/JARID2/SMAD7/MYL6/GPX1	26
GO:0002688	regulation of leukocyte chemotaxis	12/665	122/18722	0.00134484989447697	0.0105636801873288	VEGFA/DUSP1/CD74/CXCL8/C5AR1/MIF/RIN3/RAC1/WNK1/SPI1/PTK2B/CXCL12	12
GO:0002726	positive regulation of T cell cytokine production	5/665	24/18722	0.00134979611804967	0.0105636801873288	HLA-A/B2M/RSAD2/NLRP3/CD81	5
GO:0032928	regulation of superoxide anion generation	5/665	24/18722	0.00134979611804967	0.0105636801873288	ACP5/CLEC7A/ITGAM/EGFR/TYROBP	5
GO:0051000	positive regulation of nitric-oxide synthase activity	5/665	24/18722	0.00134979611804967	0.0105636801873288	APOE/CALM1/CALM3/PTK2B/PIK3CB	5
GO:0070935	3'-UTR-mediated mRNA stabilization	5/665	24/18722	0.00134979611804967	0.0105636801873288	YBX3/ZFP36/MYD88/HNRNPA0/ELAVL1	5
GO:0030865	cortical cytoskeleton organization	8/665	61/18722	0.00135818745265656	0.0105636801873288	RAC1/RHOA/RHOB/PLEC/RHOC/EPB41/RND3/RAB13	8
GO:0043030	regulation of macrophage activation	8/665	61/18722	0.00135818745265656	0.0105636801873288	FCGR2B/TREM2/JUND/CD74/MIF/HAMP/LRRK2/GRN	8
GO:0071384	cellular response to corticosteroid stimulus	8/665	61/18722	0.00135818745265656	0.0105636801873288	DDIT4/ZFP36L2/ERRFI1/ZFP36/ANXA1/EGFR/KLF9/EIF4E	8
GO:0090342	regulation of cell aging	8/665	61/18722	0.00135818745265656	0.0105636801873288	B2M/MIF/NAMPT/PTEN/LMNA/YBX1/MAP3K3/ABI3	8
GO:1905477	positive regulation of protein localization to membrane	11/665	106/18722	0.00136426942321075	0.010594404739621	TREM2/LGALS3/ITGAM/EGFR/KIF5B/STX3/SQSTM1/EPHB2/CD81/ATP2C1/PRNP	11
GO:0009259	ribonucleotide metabolic process	26/665	385/18722	0.00138742156763397	0.0107573871936674	NUPR1/LDHA/TREM2/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/ACSL1/HSD17B4/UPP1/TPI1/PAPSS1/CMPK1/GAPDH/ENO1/RHOA/PAPSS2/GPI/LRRK2/ENO2/PGAM1/GUK1/ABHD14B/GALK1	26
GO:0033157	regulation of intracellular protein transport	18/665	229/18722	0.00142513026236435	0.0110325504734437	IFI27/BNIP3L/CD36/NUP58/ITGAM/FLNA/KCNE1/HCLS1/LRRK2/PLK3/KIF5B/TXN/CAMK1/OAZ1/MDFIC/HAX1/CD81/PRNP	18
GO:0002686	negative regulation of leukocyte migration	7/665	48/18722	0.00143309389890236	0.011059746393703	CD300A/DUSP1/MIF/RIN3/HMOX1/IL27RA/CXCL12	7
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	7/665	48/18722	0.00143309389890236	0.011059746393703	ATF3/SKIL/PYCARD/PEA15/PTEN/TNFSF12/G0S2	7
GO:0033002	muscle cell proliferation	19/665	248/18722	0.00143760217826967	0.0110773377147291	APOE/JUN/STAT1/KLF4/SOD2/ANG/NAMPT/MYD88/TNFAIP3/CITED2/PTEN/HMOX1/RHOA/TRIB1/EGFR/PTAFR/CDKN1A/PHB/JARID2	19
GO:0050852	T cell receptor signaling pathway	12/665	123/18722	0.00144331424610959	0.0111041359182115	HLA-DRB1/HLA-DQB1/HLA-A/HLA-DPB1/CD300A/LGALS3/GBP1/NFKBIZ/WNK1/CD81/RIPK2/PRNP	12
GO:0050807	regulation of synapse organization	17/665	211/18722	0.00146517523594332	0.0112549009623467	FCGR2B/SRGN/TREM2/APOE/IL1RAP/TANC2/PTEN/RHOA/LRRK2/CAMK1/ABI3/EPHB2/TLR2/AGRN/CFL1/SIPA1L1/PRNP	17
GO:0048771	tissue remodeling	15/665	175/18722	0.00148353873193395	0.0113783757680737	GPNMB/ADAM8/TIMP1/ACP5/SNX10/HAMP/TNFAIP3/RASSF2/RAC1/FLNA/EGFR/MMP14/ACVRL1/PTK2B/TFRC	15
GO:0032615	interleukin-12 production	8/665	62/18722	0.00151181165056123	0.011559544466599	HLA-B/ACP5/CLEC7A/LILRA5/CD36/IRF8/TLR2/RIPK2	8
GO:0032655	regulation of interleukin-12 production	8/665	62/18722	0.00151181165056123	0.011559544466599	HLA-B/ACP5/CLEC7A/LILRA5/CD36/IRF8/TLR2/RIPK2	8
GO:0090322	regulation of superoxide metabolic process	6/665	36/18722	0.00153946533773524	0.0117348814854971	ACP5/CLEC7A/CD36/ITGAM/EGFR/TYROBP	6
GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	6/665	36/18722	0.00153946533773524	0.0117348814854971	CD74/MIF/CD44/SKIL/ZNF385A/CXCL12	6
GO:0048284	organelle fusion	13/665	141/18722	0.00156453984250422	0.0118745576270793	SAMD9/RAB8A/PIP4K2A/RAB20/BNIP3/ANXA1/VAT1/KIF5B/STX3/RAB13/ANXA2/TFRC/CHCHD3	13
GO:0050921	positive regulation of chemotaxis	13/665	141/18722	0.00156453984250422	0.0118745576270793	CXCR4/TREM2/VEGFA/CD74/CXCL8/C5AR1/RAC1/WNK1/STX3/SPI1/PTK2B/CXCL12/NRP1	13
GO:0019511	peptidyl-proline hydroxylation	4/665	15/18722	0.00157451377791655	0.0118745576270793	EGLN3/P4HA1/ERO1A/EGLN1	4
GO:0023035	CD40 signaling pathway	4/665	15/18722	0.00157451377791655	0.0118745576270793	TREM2/TNFAIP3/CD86/PHB	4
GO:0031958	corticosteroid receptor signaling pathway	4/665	15/18722	0.00157451377791655	0.0118745576270793	YWHAH/PTGES3/PHB/PER1	4
GO:0060099	regulation of phagocytosis, engulfment	4/665	15/18722	0.00157451377791655	0.0118745576270793	TREM2/CD300A/CD36/RAB31	4
GO:0140374	antiviral innate immune response	4/665	15/18722	0.00157451377791655	0.0118745576270793	IFIT1/MX1/OAS1/PHB	4
GO:0033138	positive regulation of peptidyl-serine phosphorylation	11/665	108/18722	0.00158870241644287	0.0119634106207895	VEGFA/MIF/CD44/TERF2IP/HCLS1/EGFR/TXN/CAMK1/TFRC/HAX1/RIPK2	11
GO:0032692	negative regulation of interleukin-1 production	7/665	49/18722	0.00162159967274261	0.0121926631974747	TREM2/ACP5/ERRFI1/CARD16/TNFAIP3/SERPINB1/NLRP3	7
GO:0032753	positive regulation of interleukin-4 production	5/665	25/18722	0.00163848442851711	0.0122639572435693	IL1RAP/CEBPB/CD86/HLA-E/NLRP3	5
GO:0042832	defense response to protozoan	5/665	25/18722	0.00163848442851711	0.0122639572435693	SLC11A1/CLEC7A/MYD88/IRF8/GBP4	5
GO:0048143	astrocyte activation	5/665	25/18722	0.00163848442851711	0.0122639572435693	TREM2/C5AR1/EGFR/GRN/C1QA	5
GO:0010594	regulation of endothelial cell migration	18/665	232/18722	0.00164806289525607	0.0123171016382295	VEGFA/APOE/KLF4/GLUL/CSNK2B/HMOX1/RAC1/ANXA1/RHOA/GPI/RHOB/GRN/MAP3K3/ACVRL1/PTK2B/PIK3CB/RIN2/NRP1	18
GO:0070585	protein localization to mitochondrion	12/665	125/18722	0.0016581278099369	0.0123737165396192	ISG15/HK2/CALM1/BNIP3L/TSPO/DNAJC15/RALA/LRRK2/CALM3/TIMM8B/HAX1/TIMM10	12
GO:0034504	protein localization to nucleus	21/665	290/18722	0.00167715619790067	0.0124911475140761	TXNIP/NFKBIA/GLUL/CD36/NUP58/DTX3L/PARP9/FLNA/HCLS1/LMNA/LAMTOR5/LRRK2/KPNA3/LARP7/CDKN1A/TXN/ARL2BP/TFRC/MDFIC/SUMO3/ELAVL1	21
GO:1902373	negative regulation of mRNA catabolic process	8/665	63/18722	0.00167889065179131	0.0124911475140761	SLC11A1/YBX3/ZFP36/MYD88/YBX1/HNRNPA0/TOB1/ELAVL1	8
GO:0070373	negative regulation of ERK1 and ERK2 cascade	9/665	78/18722	0.00174735875782369	0.0129811255999757	DUSP1/KLF4/ATF3/ERRFI1/PTEN/GBP1/EPHB2/PHB/DUSP6	9
GO:0070555	response to interleukin-1	13/665	143/18722	0.00177651915766239	0.0131780600202718	CXCL8/CEBPB/MYD88/PYCARD/GBP1/ANXA1/KLF2/EGR1/TANK/GBP3/CCL13/KMO/RIPK2	13
GO:0032570	response to progesterone	6/665	37/18722	0.00178307162751784	0.0132069537835524	TXNIP/TSPO/FOSB/FOS/GPI/TLR2	6
GO:0010632	regulation of epithelial cell migration	21/665	292/18722	0.00182375153252935	0.0134881623759983	VEGFA/APOE/CTSH/KLF4/GLUL/CSNK2B/PTEN/HMOX1/RAC1/ANXA1/RHOA/GPI/RHOB/GLIPR2/GRN/MAP3K3/ACVRL1/PTK2B/PIK3CB/RIN2/NRP1	21
GO:0001961	positive regulation of cytokine-mediated signaling pathway	7/665	50/18722	0.00182883913211732	0.0135056916591725	CXCR4/TREM2/CD74/IRF7/PARP9/AGPAT2/RIPK2	7
GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	9/665	79/18722	0.00191128359261117	0.0140935896962575	RNASE6/CXCL8/ANG/GAPDH/CXCL2/CXCL3/PPBP/CCL13/RPL39	9
GO:0051100	negative regulation of binding	14/665	162/18722	0.00194861317286907	0.0143475666209767	IFIT1/IFIT2/B2M/JUN/NFKBIA/DAB2/CARD16/HMOX1/LRRK2/C4orf3/CDKN1A/CAMK1/SUMO3/RSF1	14
GO:0007033	vacuole organization	15/665	180/18722	0.00195951811253071	0.0144065163007065	NUPR1/PIP4K2A/MAP1LC3B/RAB20/GABARAPL2/WDR45B/LRRK2/GRN/ATG3/WIPI2/RNF5/ANXA2/HEXB/SCARB2/CHMP5	15
GO:0001562	response to protozoan	5/665	26/18722	0.0019700292813902	0.0144624010760846	SLC11A1/CLEC7A/MYD88/IRF8/GBP4	5
GO:0043524	negative regulation of neuron apoptotic process	13/665	145/18722	0.00201169262722885	0.0147464784031377	APOE/ADAM8/CEBPB/NR4A2/C5AR1/SOD2/HMOX1/RHOA/GPI/GABRB2/GRN/PTK2B/NRP1	13
GO:0051014	actin filament severing	4/665	16/18722	0.00204083013313314	0.0148723251637415	CAPG/GSN/GMFG/CFL1	4
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	4/665	16/18722	0.00204083013313314	0.0148723251637415	STAT1/NAMPT/LRRK2/TLR2	4
GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	4/665	16/18722	0.00204083013313314	0.0148723251637415	CD74/MIF/CD44/ZNF385A	4
GO:1905153	regulation of membrane invagination	4/665	16/18722	0.00204083013313314	0.0148723251637415	TREM2/CD300A/CD36/RAB31	4
GO:0046633	alpha-beta T cell proliferation	6/665	38/18722	0.00205480720793996	0.0148787640125931	HLA-A/TNFRSF14/HLA-E/EBI3/CD81/RIPK2	6
GO:0097242	amyloid-beta clearance	6/665	38/18722	0.00205480720793996	0.0148787640125931	TREM2/APOE/C5AR1/CD36/MSR1/ITGAM	6
GO:0019693	ribose phosphate metabolic process	26/665	396/18722	0.00205496699186788	0.0148787640125931	NUPR1/LDHA/TREM2/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/ACSL1/HSD17B4/UPP1/TPI1/PAPSS1/CMPK1/GAPDH/ENO1/RHOA/PAPSS2/GPI/LRRK2/ENO2/PGAM1/GUK1/ABHD14B/GALK1	26
GO:0032970	regulation of actin filament-based process	26/665	396/18722	0.00205496699186788	0.0148787640125931	CAPG/S100A10/MYADM/BST2/GSN/GMFG/ARPC4/PYCARD/GRB2/ABRACL/RAC1/PDPN/FLNA/RHOA/HCLS1/COTL1/RHOB/RHOC/TMSB10/RND3/ABI3/PTK2B/HAX1/IQGAP2/CXCL12/NRP1	26
GO:0070613	regulation of protein processing	8/665	65/18722	0.00205668226894396	0.0148787640125931	ADAM8/CARD16/GSN/ENO1/LRRK2/MMP14/TMEM59/PRNP	8
GO:0072331	signal transduction by p53 class mediator	14/665	163/18722	0.00206406502782379	0.0149104697504131	NUPR1/DDIT4/CD74/NDRG1/SGK1/RPS27L/MIF/CD44/PYCARD/SHISA5/RRM2B/PLK3/CDKN1A/ZNF385A	14
GO:0008361	regulation of cell size	15/665	181/18722	0.00206853909616477	0.0149211020434527	VEGFA/APOE/DPYSL2/MSN/PTEN/RAC1/TMEM123/RHOA/LAMTOR5/IL7R/KCNMA1/FN1/AKT1S1/CXCL12/NRP1	15
GO:0050803	regulation of synapse structure or activity	17/665	218/18722	0.00207621346061918	0.0149547549264889	FCGR2B/SRGN/TREM2/APOE/IL1RAP/TANC2/PTEN/RHOA/LRRK2/CAMK1/ABI3/EPHB2/TLR2/AGRN/CFL1/SIPA1L1/PRNP	17
GO:0009746	response to hexose	17/665	219/18722	0.00217883389914464	0.0156712076392892	HLA-DRB1/LDHA/TREM2/LGALS1/TXNIP/SLC2A5/GLUL/DYNLL1/IRS2/NAMPT/PTEN/RAC1/RHOA/EGR1/KRT18/KIF5B/PTK2B	17
GO:0032956	regulation of actin cytoskeleton organization	24/665	357/18722	0.00220988387023066	0.0158638737822207	CAPG/S100A10/MYADM/BST2/GSN/GMFG/ARPC4/PYCARD/GRB2/RAC1/FLNA/RHOA/HCLS1/COTL1/RHOB/RHOC/TMSB10/RND3/ABI3/PTK2B/HAX1/IQGAP2/CXCL12/NRP1	24
GO:0110053	regulation of actin filament organization	20/665	277/18722	0.00221200493583077	0.0158638737822207	CAPG/S100A10/MYADM/GSN/GMFG/ARPC4/PYCARD/GRB2/RAC1/FLNA/RHOA/HCLS1/COTL1/RHOC/TMSB10/PTK2B/HAX1/IQGAP2/CXCL12/NRP1	20
GO:0032386	regulation of intracellular transport	23/665	337/18722	0.0022346246654249	0.0160030037278988	MX2/IFI27/DAB2/BNIP3L/CD36/MSN/NUP58/ITGAM/FLNA/KCNE1/HCLS1/LRRK2/PLK3/KIF5B/TXN/CAMK1/ANXA2/OAZ1/MDFIC/HAX1/CD81/SETD2/PRNP	23
GO:0031623	receptor internalization	11/665	113/18722	0.00228413835152066	0.0163105856423243	VEGFA/CD9/CXCL8/ADM/CD36/RIN3/GRB2/SDCBP/TFRC/RAB31/CD81	11
GO:0071347	cellular response to interleukin-1	11/665	113/18722	0.00228413835152066	0.0163105856423243	CXCL8/CEBPB/MYD88/PYCARD/GBP1/KLF2/EGR1/TANK/GBP3/CCL13/KMO	11
GO:0043467	regulation of generation of precursor metabolites and energy	12/665	130/18722	0.00231223663528553	0.0164875410005295	NUPR1/DDIT4/FBP1/IRS2/BNIP3/PPP1CB/PPP1R3B/DNAJC15/RHOA/PHLDA2/PGAM1/IGF2	12
GO:0007263	nitric oxide mediated signal transduction	5/665	27/18722	0.00234802291426961	0.0166709626913142	VEGFA/APOE/CD36/DDAH2/EGFR	5
GO:0031954	positive regulation of protein autophosphorylation	5/665	27/18722	0.00234802291426961	0.0166709626913142	VEGFA/GPNMB/CALM1/RASSF2/CALM3	5
GO:0032703	negative regulation of interleukin-2 production	5/665	27/18722	0.00234802291426961	0.0166709626913142	ZFP36/TNFAIP3/GBP1/LAG3/PRNP	5
GO:0017157	regulation of exocytosis	16/665	202/18722	0.00236959694152015	0.0168001380875252	FCGR2B/CD300A/CALM1/RAB8A/HLA-F/RAP1A/HMOX1/ANXA1/RALA/ITGAM/PTAFR/LRRK2/SDCBP/CALM3/SPI1/RAB13	16
GO:0030307	positive regulation of cell growth	14/665	166/18722	0.00244487497893804	0.0173091576144189	CXCR4/VEGFA/CXCL16/HAMP/RHOA/EGFR/SDCBP/S100A8/MMP14/PTK2B/FN1/CXCL12/SMAD7/NRP1	14
GO:0072594	establishment of protein localization to organelle	27/665	422/18722	0.00244985129995312	0.0173197168716458	TXNIP/NFKBIA/HK2/CALM1/BNIP3L/TSPO/CD36/TNFAIP3/NUP58/SEC61G/DNAJC15/RALA/FLNA/HCLS1/LMNA/LRRK2/KPNA3/CALM3/TIMM8B/CDKN1A/SCARB2/MDFIC/HAX1/TIMM10/ELAVL1/VPS13A/CD68	27
GO:0051091	positive regulation of DNA-binding transcription factor activity	19/665	260/18722	0.00246315753572652	0.017389052489433	VEGFA/ADAM8/EIF2AK2/IL1RAP/TRIM22/CLEC7A/CARD16/CD36/TERF2IP/MYD88/PYCARD/PTEN/HCLS1/LAMTOR5/S100A8/TFRC/TLR2/NLRP3/RIPK2	19
GO:1903317	regulation of protein maturation	8/665	67/18722	0.00249831989177074	0.0176122693079441	ADAM8/CARD16/GSN/ENO1/LRRK2/MMP14/TMEM59/PRNP	8
GO:0002040	sprouting angiogenesis	15/665	185/18722	0.00255635118691935	0.0179958433413444	VEGFA/ALOX5/KLF4/GLUL/PKM/HMOX1/ANXA1/KLF2/RHOA/MAP3K3/ACVRL1/PTK2B/PIK3CB/NR4A1/NRP1	15
GO:0007254	JNK cascade	14/665	167/18722	0.00258399387595034	0.0181647094249974	FCGR2B/NCF1/MYD88/PYCARD/RASSF2/TRIB1/EGFR/AIDA/LRRK2/SDCBP/PTK2B/MDFIC/PER1/RIPK2	14
GO:0016045	detection of bacterium	4/665	17/18722	0.00259447749464666	0.0181869578961832	HLA-DRB1/HLA-A/HLA-B/TLR2	4
GO:0060263	regulation of respiratory burst	4/665	17/18722	0.00259447749464666	0.0181869578961832	CLEC7A/NCF1/RAC1/GRN	4
GO:1903320	regulation of protein modification by small protein conjugation or removal	18/665	242/18722	0.00261538614157777	0.0182846432601446	ISG15/NMI/TSPO/N4BP1/TNFAIP3/PTEN/DTX3L/EGR1/ARRDC3/RBX1/LRRK2/TANK/SQSTM1/UBE2D1/IVNS1ABP/CAMLG/SMAD7/RIPK2	18
GO:1901888	regulation of cell junction assembly	16/665	204/18722	0.00261589216820433	0.0182846432601446	VEGFA/LIMS1/IL1RAP/S100A10/RAP1A/PTEN/RAC1/RAPGEF1/RHOA/MMP14/ACVRL1/ABI3/EPHB2/TLR2/AGRN/NRP1	16
GO:0046916	cellular transition metal ion homeostasis	11/665	115/18722	0.00262359293757691	0.0182846432601446	SLC11A1/FTH1/HAMP/SCO2/MT1X/HMOX1/ATP6V1G1/FTL/S100A8/TFRC/PRNP	11
GO:0042063	gliogenesis	21/665	301/18722	0.00262559100225293	0.0182846432601446	VIM/CXCR4/TREM2/GPR183/CD9/NDRG1/C5AR1/TSPO/BNIP3/PTEN/ANXA1/RHOA/EGFR/PLEC/GRN/S100A8/MMP14/PTK2B/HEXB/TLR2/C1QA	21
GO:0007569	cell aging	12/665	132/18722	0.00262680790497853	0.0182846432601446	B2M/LIMS1/MIF/NAMPT/CITED2/PTEN/LMNA/YBX1/MAP3K3/SPI1/CDKN1A/ABI3	12
GO:0050920	regulation of chemotaxis	17/665	223/18722	0.00263276764259126	0.0183004967603896	CXCR4/TREM2/VEGFA/GPR183/DUSP1/CD74/CXCL8/C5AR1/MIF/RIN3/RAC1/WNK1/STX3/SPI1/PTK2B/CXCL12/NRP1	17
GO:0010466	negative regulation of peptidase activity	19/665	262/18722	0.00268293788978143	0.0185687902046763	VEGFA/TIMP1/KLF4/IFI6/CARD16/ECM1/SERPING1/CD44/BST2/GAPDH/CSTB/GPI/LAMTOR5/PLAUR/ANXA2/NR4A1/SERPINB1/PRNP/GPX1	19
GO:0045429	positive regulation of nitric oxide biosynthetic process	6/665	40/18722	0.0026907286123802	0.0185687902046763	KLF4/CLEC7A/CD36/DDAH2/KLF2/PTK2B	6
GO:0071276	cellular response to cadmium ion	6/665	40/18722	0.0026907286123802	0.0185687902046763	JUN/NCF1/MT1X/HMOX1/FOS/EGFR	6
GO:1901223	negative regulation of NIK/NF-kappaB signaling	6/665	40/18722	0.0026907286123802	0.0185687902046763	NMI/RASSF2/LITAF/IFI35/SPI1/NLRP3	6
GO:0031397	negative regulation of protein ubiquitination	9/665	83/18722	0.00269378224096008	0.0185687902046763	ISG15/TSPO/N4BP1/TNFAIP3/DTX3L/SQSTM1/IVNS1ABP/CAMLG/SMAD7	9
GO:0048678	response to axon injury	9/665	83/18722	0.00269378224096008	0.0185687902046763	TREM2/LGALS1/KLF4/TSPO/BNIP3/PTEN/FLNA/GRN/TYROBP	9
GO:0002444	myeloid leukocyte mediated immunity	10/665	99/18722	0.00271489942280856	0.0186368095736996	FCGR2B/CD300A/MYD88/TREM1/HMOX1/ITGAM/PTAFR/SPI1/HLA-E/TYROBP	10
GO:0033209	tumor necrosis factor-mediated signaling pathway	10/665	99/18722	0.00271489942280856	0.0186368095736996	LIMS1/NFKBIA/STAT1/TNFSF13B/CARD16/PYCARD/TNFAIP3/TNFRSF14/KRT18/PTK2B	10
GO:0060996	dendritic spine development	10/665	99/18722	0.00271489942280856	0.0186368095736996	APOE/TANC2/PTEN/LRRK2/UBA6/CAMK1/ABI3/EPHB2/CFL1/SIPA1L1	10
GO:0060348	bone development	16/665	205/18722	0.00274678970833504	0.0188297170350692	SULF2/ACP5/SNX10/PIP4K2A/ABI1/CITED2/RHOA/DHRS3/INSIG2/MMP14/VKORC1/FOXN3/ANXA2/TYROBP/ZNF385A/HSD17B1	16
GO:0051894	positive regulation of focal adhesion assembly	5/665	28/18722	0.00277608926440383	0.0189521478627569	VEGFA/LIMS1/S100A10/RAC1/NRP1	5
GO:0090344	negative regulation of cell aging	5/665	28/18722	0.00277608926440383	0.0189521478627569	MIF/NAMPT/PTEN/YBX1/MAP3K3	5
GO:1902624	positive regulation of neutrophil migration	5/665	28/18722	0.00277608926440383	0.0189521478627569	CD74/ADAM8/CXCL8/C5AR1/RAC1	5
GO:0050808	synapse organization	27/665	426/18722	0.00279121747106527	0.0189882816480395	FCGR2B/SRGN/TREM2/APOE/NDRG1/IL1RAP/C5AR1/C1QB/TANC2/C1QC/PTEN/ITGAM/FLNA/RHOA/GABRB2/LRRK2/SDCBP/CAMK1/ABI3/EPHB2/TLR2/AGRN/CFL1/SIPA1L1/PRNP/C1QA/NRP1	27
GO:0010595	positive regulation of endothelial cell migration	12/665	133/18722	0.00279666441979174	0.0189882816480395	VEGFA/HMOX1/RAC1/ANXA1/GPI/RHOB/GRN/MAP3K3/PTK2B/PIK3CB/RIN2/NRP1	12
GO:0046328	regulation of JNK cascade	12/665	133/18722	0.00279666441979174	0.0189882816480395	FCGR2B/NCF1/MYD88/PYCARD/RASSF2/EGFR/AIDA/SDCBP/PTK2B/MDFIC/PER1/RIPK2	12
GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process	12/665	133/18722	0.00279666441979174	0.0189882816480395	NUPR1/TREM2/DAB2/SUMO2/PTEN/TRIB1/RBX1/LRRK2/PSMC6/PLK3/PTK2B/SMAD7	12
GO:0008064	regulation of actin polymerization or depolymerization	15/665	187/18722	0.00283381807341091	0.0192142917119403	CAPG/MYADM/GSN/GMFG/ARPC4/PYCARD/GRB2/RHOA/HCLS1/COTL1/TMSB10/PTK2B/HAX1/IQGAP2/CXCL12	15
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	7/665	54/18722	0.00287012608740854	0.0194339600196464	FCGR2B/IL4I1/AHR/HLA-F/IL7R/IL27RA/SMAD7	7
GO:0016485	protein processing	17/665	225/18722	0.00288772788161511	0.0195265409137784	SRGN/CAPN2/CTSH/ADAM8/PGK1/CARD16/GSN/PYCARD/ENO1/LRRK2/MMP14/PLAU/APH1A/TMEM59/CPD/RIPK2/PRNP	17
GO:0006970	response to osmotic stress	9/665	84/18722	0.002924317992904	0.0197470929683871	TSC22D3/YBX3/ERRFI1/TSPO/EGFR/PLK3/PTK2B/KCNMA1/KMO	9
GO:0030832	regulation of actin filament length	15/665	188/18722	0.00298159804166716	0.0201065702402793	CAPG/MYADM/GSN/GMFG/ARPC4/PYCARD/GRB2/RHOA/HCLS1/COTL1/TMSB10/PTK2B/HAX1/IQGAP2/CXCL12	15
GO:0050688	regulation of defense response to virus	8/665	69/18722	0.00301089191848022	0.0202766027572448	IFIT1/HERC5/STAT1/FGL2/PYCARD/TNFAIP3/DTX3L/PARP9	8
GO:0050679	positive regulation of epithelial cell proliferation	16/665	207/18722	0.00302490363462706	0.0203433979216461	VEGFA/JAML/GLUL/C5AR1/ECM1/ANG/TNFAIP3/HMOX1/EGFR/TNFSF12/GRN/ACVRL1/IGF2/NR4A1/CXCL12/NRP1	16
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	6/665	41/18722	0.00305903351167185	0.0204897527668586	LIMS1/S100A10/MYADM/RAC1/FLNA/NRP1	6
GO:1902622	regulation of neutrophil migration	6/665	41/18722	0.00305903351167185	0.0204897527668586	CD74/ADAM8/CXCL8/C5AR1/MYD88/RAC1	6
GO:1904407	positive regulation of nitric oxide metabolic process	6/665	41/18722	0.00305903351167185	0.0204897527668586	KLF4/CLEC7A/CD36/DDAH2/KLF2/PTK2B	6
GO:1901215	negative regulation of neuron death	16/665	208/18722	0.00317245665743609	0.021220874276524	GPNMB/APOE/ADAM8/CEBPB/NR4A2/C5AR1/SOD2/HLA-F/HMOX1/RHOA/GPI/GABRB2/LRRK2/GRN/PTK2B/NRP1	16
GO:0030833	regulation of actin filament polymerization	14/665	171/18722	0.00320722212811012	0.02142458867837	CAPG/MYADM/GSN/GMFG/ARPC4/PYCARD/GRB2/RHOA/HCLS1/COTL1/TMSB10/PTK2B/HAX1/IQGAP2	14
GO:0034134	toll-like receptor 2 signaling pathway	4/665	18/18722	0.003243006233523	0.0215190133252461	TREM2/TNFAIP3/TLR2/RIPK2	4
GO:0043217	myelin maintenance	4/665	18/18722	0.003243006233523	0.0215190133252461	CXCR4/NDRG1/PTEN/PLEC	4
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	4/665	18/18722	0.003243006233523	0.0215190133252461	HLA-A/HLA-B/HLA-F/HLA-E	4
GO:0060192	negative regulation of lipase activity	4/665	18/18722	0.003243006233523	0.0215190133252461	APOC1/ANXA1/RGS2/ANGPTL4	4
GO:1900225	regulation of NLRP3 inflammasome complex assembly	4/665	18/18722	0.003243006233523	0.0215190133252461	TREM2/EIF2AK2/CD36/MYD88	4
GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	5/665	29/18722	0.00325786808745084	0.0215600591140222	CD74/MIF/CD44/ZNF385A/CXCL12	5
GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	5/665	29/18722	0.00325786808745084	0.0215600591140222	CD74/MIF/CD44/RRM2B/ZNF385A	5
GO:0009150	purine ribonucleotide metabolic process	24/665	368/18722	0.00326294985456168	0.0215649744377281	NUPR1/LDHA/TREM2/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/ACSL1/HSD17B4/TPI1/PAPSS1/GAPDH/ENO1/RHOA/PAPSS2/GPI/LRRK2/ENO2/PGAM1/GUK1/ABHD14B/GALK1	24
GO:0031396	regulation of protein ubiquitination	16/665	210/18722	0.00348541880003026	0.0230046898222449	ISG15/NMI/TSPO/N4BP1/TNFAIP3/PTEN/DTX3L/ARRDC3/RBX1/LRRK2/SQSTM1/UBE2D1/IVNS1ABP/CAMLG/SMAD7/RIPK2	16
GO:0010518	positive regulation of phospholipase activity	7/665	56/18722	0.00353643640544624	0.0232487948876558	C5AR1/GNAQ/ANG/EGFR/PTAFR/CD86/PHB	7
GO:0043470	regulation of carbohydrate catabolic process	7/665	56/18722	0.00353643640544624	0.0232487948876558	NUPR1/DDIT4/FBP1/PPP1CB/PPP1R3B/PGAM1/SCARB2	7
GO:0048255	mRNA stabilization	7/665	56/18722	0.00353643640544624	0.0232487948876558	SLC11A1/YBX3/ZFP36/MYD88/YBX1/HNRNPA0/ELAVL1	7
GO:0030218	erythrocyte differentiation	11/665	120/18722	0.00365265535871753	0.0239494685129632	ISG15/VEGFA/B2M/STAT1/ZFP36/MAFB/CITED2/KLF2/HCLS1/SPI1/RB1	11
GO:0072655	establishment of protein localization to mitochondrion	11/665	120/18722	0.00365265535871753	0.0239494685129632	HK2/CALM1/BNIP3L/TSPO/DNAJC15/RALA/LRRK2/CALM3/TIMM8B/HAX1/TIMM10	11
GO:0019915	lipid storage	9/665	87/18722	0.0037104915535761	0.0242646618700964	PLIN2/TREM2/APOE/NFKBIA/CD36/MSR1/SOAT1/HEXB/ABHD5	9
GO:1903578	regulation of ATP metabolic process	9/665	87/18722	0.0037104915535761	0.0242646618700964	NUPR1/TREM2/DDIT4/FBP1/TSPO/ENO1/DNAJC15/RHOA/PGAM1	9
GO:0043434	response to peptide hormone	26/665	414/18722	0.00373648131067052	0.0244025126334198	JUND/STAT1/BTG1/TIMP1/PKM/NR4A2/ADM/ERRFI1/RAB8A/IRS2/PIP4K2A/GRB2/PTEN/SOCS3/ANXA1/EGR1/INSIG2/RAB13/CACYBP/GCNT1/IGF2/TLR2/NR4A1/RAB31/CPEB2/CXCL12	26
GO:0044788	modulation by host of viral process	5/665	30/18722	0.00379699954406922	0.0247003766152147	APOE/IFI27/PHB/ZBED1/CFL1	5
GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	5/665	30/18722	0.00379699954406922	0.0247003766152147	FCGR2B/CD300A/LGALS3/GBP1/PRNP	5
GO:0070229	negative regulation of lymphocyte apoptotic process	5/665	30/18722	0.00379699954406922	0.0247003766152147	TSC22D3/CD74/IRS2/IL7R/DOCK8	5
GO:0001935	endothelial cell proliferation	15/665	193/18722	0.00381889123360873	0.0248103129817456	VEGFA/APOE/STAT1/ALOX5/ECM1/ANG/PRKX/HMOX1/TNFSF12/MMP14/ACVRL1/IGF2/NR4A1/CXCL12/NRP1	15
GO:0048732	gland development	27/665	436/18722	0.00382599606961407	0.02482402149606	OAS2/VEGFA/SULF2/HK2/CRIP1/CEBPB/CSNK2B/TSPO/IRS2/HAMP/RAP1A/MAFB/MSN/LY6E/CGA/TNFAIP3/CITED2/PTEN/HMOX1/ANXA1/EGFR/KRT18/IGF2/JARID2/PSAP/GPX1/NRP1	27
GO:0002429	immune response-activating cell surface receptor signaling pathway	20/665	291/18722	0.00388096109134307	0.0250824143354682	FCGR2B/HLA-DRB1/HLA-DQB1/FPR3/HLA-A/HLA-DPB1/CD300A/MYO1G/PLSCR1/CLEC7A/C5AR1/RAP1A/LGALS3/GBP1/NFKBIZ/WNK1/TYROBP/CD81/RIPK2/PRNP	20
GO:0002757	immune response-activating signal transduction	20/665	291/18722	0.00388096109134307	0.0250824143354682	FCGR2B/HLA-DRB1/HLA-DQB1/FPR3/HLA-A/HLA-DPB1/CD300A/MYO1G/PLSCR1/CLEC7A/C5AR1/RAP1A/LGALS3/GBP1/NFKBIZ/WNK1/TYROBP/CD81/RIPK2/PRNP	20
GO:0016236	macroautophagy	20/665	291/18722	0.00388096109134307	0.0250824143354682	NUPR1/CALM1/BNIP3L/PIP4K2A/MAP1LC3B/GAPDH/BNIP3/GABARAPL2/HMOX1/ATP6V1G1/WDR45B/LRRK2/CAPNS1/ATP6V1B2/SQSTM1/ATG3/WIPI2/RNF5/VTA1/RIPK2	20
GO:0002861	regulation of inflammatory response to antigenic stimulus	6/665	43/18722	0.00390683520472988	0.0251440935102813	FCGR2B/HLA-DRB1/TREM2/HLA-E/CD81/GPX1	6
GO:0031952	regulation of protein autophosphorylation	6/665	43/18722	0.00390683520472988	0.0251440935102813	VEGFA/GPNMB/CALM1/ERRFI1/RASSF2/CALM3	6
GO:0042088	T-helper 1 type immune response	6/665	43/18722	0.00390683520472988	0.0251440935102813	SLC11A1/HLA-DRB1/ANXA1/IL27RA/EBI3/RIPK2	6
GO:0061756	leukocyte adhesion to vascular endothelial cell	7/665	57/18722	0.00391074130451659	0.0251440935102813	ALOX5/KLF4/RHOA/PTAFR/SELPLG/GCNT1/CXCL12	7
GO:0030330	DNA damage response, signal transduction by p53 class mediator	8/665	72/18722	0.00392898657553169	0.0251962106843774	CD74/NDRG1/RPS27L/MIF/CD44/PLK3/CDKN1A/ZNF385A	8
GO:0070227	lymphocyte apoptotic process	8/665	72/18722	0.00392898657553169	0.0251962106843774	TSC22D3/CD74/ADAM8/IRS2/LGALS3/PTEN/IL7R/DOCK8	8
GO:0019932	second-messenger-mediated signaling	21/665	312/18722	0.00399070247464201	0.0254472785863241	CXCR4/TREM2/VEGFA/APOE/CALM1/CXCL8/CLEC7A/ADM/AHR/CD36/UBE2B/CLIC2/GBP1/DDAH2/RGS2/EGFR/LRRK2/CALM3/PTK2B/CAP1/PRNP	21
GO:0002523	leukocyte migration involved in inflammatory response	4/665	19/18722	0.00399373788678728	0.0254472785863241	ADAM8/ALOX5/S100A8/NLRP3	4
GO:0002716	negative regulation of natural killer cell mediated immunity	4/665	19/18722	0.00399373788678728	0.0254472785863241	HLA-A/HLA-B/HLA-F/HLA-E	4
GO:0031290	retinal ganglion cell axon guidance	4/665	19/18722	0.00399373788678728	0.0254472785863241	ALCAM/VEGFA/EPHB2/NRP1	4
GO:0044546	NLRP3 inflammasome complex assembly	4/665	19/18722	0.00399373788678728	0.0254472785863241	TREM2/EIF2AK2/CD36/MYD88	4
GO:0010951	negative regulation of endopeptidase activity	18/665	252/18722	0.00401756238894547	0.0255663061114712	VEGFA/TIMP1/KLF4/IFI6/CARD16/SERPING1/CD44/BST2/GAPDH/CSTB/GPI/LAMTOR5/PLAUR/ANXA2/NR4A1/SERPINB1/PRNP/GPX1	18
GO:0007160	cell-matrix adhesion	17/665	233/18722	0.0041216207327338	0.0261949552962749	VEGFA/LIMS1/S100A10/CD44/CD36/LYVE1/PTEN/RAC1/RHOA/MMP14/PLAU/ACVRL1/PTK2B/PIK3CB/FN1/RIN2/NRP1	17
GO:0010634	positive regulation of epithelial cell migration	14/665	176/18722	0.00415391906940063	0.0263665105682262	VEGFA/CTSH/HMOX1/RAC1/ANXA1/GPI/RHOB/GLIPR2/GRN/MAP3K3/PTK2B/PIK3CB/RIN2/NRP1	14
GO:0016049	cell growth	29/665	482/18722	0.0041848992885959	0.0265292722759204	CXCR4/ALCAM/VEGFA/APOE/BTG1/SGK1/FBP1/DPYSL2/BST2/CXCL16/HAMP/ENO1/OGFR/RHOA/RGS2/EGFR/SDCBP/S100A8/MMP14/CDKN1A/ACVRL1/PTK2B/RB1/FN1/CCDC85B/PHB/CXCL12/SMAD7/NRP1	29
GO:0002637	regulation of immunoglobulin production	8/665	73/18722	0.00427865589031911	0.0270546053115598	FCGR2B/GPI/IL27RA/CD86/HLA-E/TFRC/EPHB2/PHB	8
GO:0050848	regulation of calcium-mediated signaling	8/665	73/18722	0.00427865589031911	0.0270546053115598	TREM2/CALM1/CLEC7A/GBP1/LRRK2/CALM3/PTK2B/PRNP	8
GO:0006826	iron ion transport	7/665	58/18722	0.00431433424516876	0.0272109659879299	SLC11A1/B2M/SLC25A37/FTH1/HAMP/FTL/TFRC	7
GO:0010043	response to zinc ion	7/665	58/18722	0.00431433424516876	0.0272109659879299	CRIP1/SOD2/TSPO/HAMP/MT1X/PTEN/S100A8	7
GO:1900407	regulation of cellular response to oxidative stress	9/665	89/18722	0.00432046901438563	0.0272151216749006	TREM2/PAGE4/ALOX5/SOD2/CD36/MCL1/LRRK2/TXN/GPX1	9
GO:0042269	regulation of natural killer cell mediated cytotoxicity	6/665	44/18722	0.00439059227058591	0.0274543132493198	HLA-A/HLA-B/HLA-F/CADM1/LAG3/HLA-E	6
GO:0042554	superoxide anion generation	6/665	44/18722	0.00439059227058591	0.0274543132493198	ACP5/CLEC7A/NCF1/ITGAM/EGFR/TYROBP	6
GO:0062208	positive regulation of pattern recognition receptor signaling pathway	6/665	44/18722	0.00439059227058591	0.0274543132493198	RSAD2/IFI35/DDX60/OASL/TLR2/WDFY1	6
GO:0001782	B cell homeostasis	5/665	31/18722	0.00439710932524317	0.0274543132493198	CD74/TNFSF13B/TNFAIP3/SOS2/CAMLG	5
GO:0007190	activation of adenylate cyclase activity	5/665	31/18722	0.00439710932524317	0.0274543132493198	CALM1/ADORA3/TMIGD3/CALM3/CAP1	5
GO:0060055	angiogenesis involved in wound healing	5/665	31/18722	0.00439710932524317	0.0274543132493198	CXCR4/VEGFA/ALOX5/TNFAIP3/GPX1	5
GO:1901797	negative regulation of signal transduction by p53 class mediator	5/665	31/18722	0.00439710932524317	0.0274543132493198	CD74/MIF/CD44/RRM2B/ZNF385A	5
GO:0010811	positive regulation of cell-substrate adhesion	11/665	123/18722	0.00441057716511175	0.0275038500760419	VEGFA/LIMS1/S100A10/MYADM/CD36/RAC1/FLNA/PTK2B/FN1/RIN2/NRP1	11
GO:0015911	long-chain fatty acid import across plasma membrane	3/665	10/18722	0.00444037877353152	0.0275170604793662	ACSL1/CD36/IRS2	3
GO:0031340	positive regulation of vesicle fusion	3/665	10/18722	0.00444037877353152	0.0275170604793662	ANXA1/KIF5B/ANXA2	3
GO:0045792	negative regulation of cell size	3/665	10/18722	0.00444037877353152	0.0275170604793662	PTEN/RHOA/AKT1S1	3
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	3/665	10/18722	0.00444037877353152	0.0275170604793662	CALM1/EGLN1/CALM3	3
GO:1902946	protein localization to early endosome	3/665	10/18722	0.00444037877353152	0.0275170604793662	MSN/DTX3L/NRP1	3
GO:0046822	regulation of nucleocytoplasmic transport	10/665	106/18722	0.00445421614939494	0.0275684361923946	MX2/IFI27/CD36/NUP58/FLNA/HCLS1/TXN/CAMK1/MDFIC/SETD2	10
GO:0051170	import into nucleus	13/665	159/18722	0.00447590126103857	0.0276681956061712	TXNIP/NFKBIA/CD36/NUP58/FLNA/HCLS1/LMNA/LRRK2/KPNA3/CDKN1A/HNRNPA1/MDFIC/ELAVL1	13
GO:0034329	cell junction assembly	26/665	420/18722	0.00450775250641332	0.027830471996117	VEGFA/CD9/LIMS1/IL1RAP/S100A10/RAP1A/PTEN/RAC1/RAPGEF1/RHOA/GABRB2/PLEC/RHOC/DST/SDCBP/MMP14/ACVRL1/RAB13/ABI3/PTK2B/EPHB2/FN1/TLR2/AGRN/SMAD7/NRP1	26
GO:0006801	superoxide metabolic process	8/665	74/18722	0.00465178603845512	0.0286584433015969	ACP5/CLEC7A/SOD2/NCF1/CD36/ITGAM/EGFR/TYROBP	8
GO:0034109	homotypic cell-cell adhesion	9/665	90/18722	0.00465339310752287	0.0286584433015969	LGALS1/CD9/CLIC1/PDPN/FLNA/PLAUR/MYL12A/PIK3CB/FN1	9
GO:0007265	Ras protein signal transduction	22/665	337/18722	0.00467759833782186	0.0287718610630875	APOE/JUN/FBP1/SHOC2/RAP1A/GRB2/RAC1/RAPGEF1/PDPN/RALA/RHOA/PPP2CB/RHOB/SDCBP/CDKN1A/SQSTM1/RAB42/RB1/PIK3CB/EPHB2/CFL1/NRP1	22
GO:0032768	regulation of monooxygenase activity	7/665	59/18722	0.0047486251470121	0.0291726415088383	APOE/CALM1/DDAH2/EGFR/CALM3/PTK2B/PIK3CB	7
GO:0010801	negative regulation of peptidyl-threonine phosphorylation	4/665	20/18722	0.00485372461777859	0.0296716006769491	DDIT4/CALM1/CALM3/SMAD7	4
GO:0032930	positive regulation of superoxide anion generation	4/665	20/18722	0.00485372461777859	0.0296716006769491	CLEC7A/ITGAM/EGFR/TYROBP	4
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	4/665	20/18722	0.00485372461777859	0.0296716006769491	ISG15/OAS1/OAS3/USP18	4
GO:0140632	inflammasome complex assembly	4/665	20/18722	0.00485372461777859	0.0296716006769491	TREM2/EIF2AK2/CD36/MYD88	4
GO:0019318	hexose metabolic process	17/665	237/18722	0.00488472709263058	0.0298244393739238	OAS1/HK2/PGK1/FBP1/ALDOA/ATF3/TPI1/IRS2/GAPDH/PPP1CB/ENO1/PPP1R3B/GPI/CHST15/PHLDA2/IGF2/GALK1	17
GO:0071364	cellular response to epidermal growth factor stimulus	6/665	45/18722	0.00491711327989763	0.0299853411056334	ZFP36L2/ERRFI1/ZFP36/PTPN12/EGFR/NCL	6
GO:0005996	monosaccharide metabolic process	18/665	257/18722	0.00492319335472238	0.0299856261923655	OAS1/HK2/PGK1/FBP1/ALDOA/ATF3/TPI1/IRS2/GAPDH/PPP1CB/ENO1/PPP1R3B/SLC2A3/GPI/CHST15/PHLDA2/IGF2/GALK1	18
GO:0010975	regulation of neuron projection development	27/665	445/18722	0.00501756164370275	0.0305229882119984	VIM/LGALS1/VEGFA/B2M/APOE/YWHAH/KLF4/SKIL/RAP1A/TANC2/PTEN/RAPGEF1/FLNA/RHOA/RGS2/LRRK2/GRN/CAMK1/ABI3/PTK2B/EPHB2/FN1/SCARB2/CFL1/CXCL12/SIPA1L1/NRP1	27
GO:0034763	negative regulation of transmembrane transport	12/665	143/18722	0.00503629860750618	0.0305995159893713	CALM1/IRS2/HAMP/CLIC2/PEA15/PTEN/KCNE1/RGS2/CALM3/C4orf3/EPHB2/OAZ1	12
GO:1902369	negative regulation of RNA catabolic process	8/665	75/18722	0.00504938047668745	0.0306415396448554	SLC11A1/YBX3/ZFP36/MYD88/YBX1/HNRNPA0/TOB1/ELAVL1	8
GO:1905476	negative regulation of protein localization to membrane	5/665	32/18722	0.00506179437547485	0.0306794122513536	DAB2/GBP1/KCNE1/ABI3/TMEM59	5
GO:0048608	reproductive structure development	26/665	424/18722	0.00509277186474309	0.0308295690228662	NUPR1/VEGFA/CRIP1/CEBPB/YBX3/MERTK/ADM/HSD17B4/ST14/ANG/IDH1/JUNB/CGA/GRB2/CITED2/PTEN/SOCS3/ANXA1/FLNA/PHLDA2/MMP14/RAB13/IGF2/TIPARP/SETD2/PSAP	26
GO:0009620	response to fungus	7/665	60/18722	0.00521503588763974	0.0314166404382661	CLEC7A/HAMP/MYD88/GAPDH/COTL1/S100A8/SPI1	7
GO:0031638	zymogen activation	7/665	60/18722	0.00521503588763974	0.0314166404382661	CTSH/PGK1/PYCARD/ENO1/MMP14/PLAU/RIPK2	7
GO:0051851	modulation by host of symbiont process	7/665	60/18722	0.00521503588763974	0.0314166404382661	SAP30/APOE/IFI27/JUN/PHB/ZBED1/CFL1	7
GO:1903670	regulation of sprouting angiogenesis	7/665	60/18722	0.00521503588763974	0.0314166404382661	VEGFA/ALOX5/KLF4/GLUL/PKM/KLF2/PIK3CB	7
GO:0010498	proteasomal protein catabolic process	29/665	490/18722	0.00524997964105731	0.0315888605521245	NUPR1/TREM2/APOE/IFI27/PSMB9/DAB2/SUMO2/PSME2/PSMB8/UBE2B/N4BP1/GABARAPL2/PSMB10/SMURF2/PPP2CB/TRIB1/SPOP/RBX1/LRRK2/SDCBP/PSMC6/PLK3/FBXL15/RNF187/RNF5/CAMLG/FBXL5/SMAD7/GPX1	29
GO:2001235	positive regulation of apoptotic signaling pathway	11/665	126/18722	0.00528847892664243	0.0317820317598705	NUPR1/CTSH/ATF3/SKIL/PYCARD/PEA15/MCL1/PTEN/TNFSF12/S100A8/G0S2	11
GO:0032720	negative regulation of tumor necrosis factor production	8/665	76/18722	0.00547245302248805	0.0328479366204899	TREM2/GPNMB/ACP5/ERRFI1/TSPO/TNFAIP3/CLEC4A/IL27RA	8
GO:0061028	establishment of endothelial barrier	6/665	46/18722	0.00548854940395398	0.0329048136762983	VEGFA/MYADM/RAP1A/MYD88/MSN/RAPGEF1	6
GO:0061458	reproductive system development	26/665	427/18722	0.00557202632706958	0.0333650251151034	NUPR1/VEGFA/CRIP1/CEBPB/YBX3/MERTK/ADM/HSD17B4/ST14/ANG/IDH1/JUNB/CGA/GRB2/CITED2/PTEN/SOCS3/ANXA1/FLNA/PHLDA2/MMP14/RAB13/IGF2/TIPARP/SETD2/PSAP	26
GO:0060997	dendritic spine morphogenesis	7/665	61/18722	0.00571499772180424	0.0341799502736066	TANC2/PTEN/LRRK2/ABI3/EPHB2/CFL1/SIPA1L1	7
GO:0032088	negative regulation of NF-kappaB transcription factor activity	9/665	93/18722	0.00577288517236439	0.0343290068358042	NFKBIA/ADORA3/KLF4/TMIGD3/PYCARD/TNFAIP3/SPI1/CYP1B1/NLRP3	9
GO:0001975	response to amphetamine	5/665	33/18722	0.00579460926231591	0.0343290068358042	CALM1/NR4A2/RGS2/CALM3/NR4A1	5
GO:0036336	dendritic cell migration	5/665	33/18722	0.00579460926231591	0.0343290068358042	CXCR4/GPR183/ALOX5/SPI1/DOCK8	5
GO:0150117	positive regulation of cell-substrate junction organization	5/665	33/18722	0.00579460926231591	0.0343290068358042	VEGFA/LIMS1/S100A10/RAC1/NRP1	5
GO:0050806	positive regulation of synaptic transmission	13/665	164/18722	0.00579615877978214	0.0343290068358042	APOE/GLUL/SLC1A3/PTEN/EGFR/KIF5B/STX3/PTK2B/SQSTM1/TYROBP/EPHB2/KMO/PRNP	13
GO:0010878	cholesterol storage	4/665	21/18722	0.00582971464173416	0.0343290068358042	TREM2/CD36/MSR1/SOAT1	4
GO:0032516	positive regulation of phosphoprotein phosphatase activity	4/665	21/18722	0.00582971464173416	0.0343290068358042	CD300A/CALM1/PPP1R15A/CALM3	4
GO:0044342	type B pancreatic cell proliferation	4/665	21/18722	0.00582971464173416	0.0343290068358042	NUPR1/ERRFI1/NR4A1/SERPINB1	4
GO:0045655	regulation of monocyte differentiation	4/665	21/18722	0.00582971464173416	0.0343290068358042	HLA-DRB1/CD74/JUN/IRF7	4
GO:0051767	nitric-oxide synthase biosynthetic process	4/665	21/18722	0.00582971464173416	0.0343290068358042	STAT1/NAMPT/LRRK2/TLR2	4
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	4/665	21/18722	0.00582971464173416	0.0343290068358042	STAT1/NAMPT/LRRK2/TLR2	4
GO:0071498	cellular response to fluid shear stress	4/665	21/18722	0.00582971464173416	0.0343290068358042	KLF4/KLF2/PLEC/PTK2B	4
GO:0097062	dendritic spine maintenance	4/665	21/18722	0.00582971464173416	0.0343290068358042	FCGR2B/TREM2/APOE/PRNP	4
GO:0010675	regulation of cellular carbohydrate metabolic process	12/665	146/18722	0.00593277453321894	0.0344804804286829	NUPR1/DDIT4/FBP1/IRS2/PPP1CB/PPP1R3B/PTAFR/PHLDA2/PGAM1/PTK2B/IGF2/SCARB2	12
GO:0002357	defense response to tumor cell	3/665	11/18722	0.00594562811416122	0.0344804804286829	KLF4/SPI1/ABI3	3
GO:0019372	lipoxygenase pathway	3/665	11/18722	0.00594562811416122	0.0344804804286829	ALOX5/ALOX5AP/GPX1	3
GO:0034115	negative regulation of heterotypic cell-cell adhesion	3/665	11/18722	0.00594562811416122	0.0344804804286829	KLF4/MYADM/WNK1	3
GO:0043312	neutrophil degranulation	3/665	11/18722	0.00594562811416122	0.0344804804286829	ITGAM/PTAFR/SPI1	3
GO:0045628	regulation of T-helper 2 cell differentiation	3/665	11/18722	0.00594562811416122	0.0344804804286829	ANXA1/CD86/NLRP3	3
GO:0045657	positive regulation of monocyte differentiation	3/665	11/18722	0.00594562811416122	0.0344804804286829	HLA-DRB1/CD74/JUN	3
GO:0046598	positive regulation of viral entry into host cell	3/665	11/18722	0.00594562811416122	0.0344804804286829	HLA-DRB1/LGALS1/CD74	3
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	3/665	11/18722	0.00594562811416122	0.0344804804286829	CALM1/CLIC2/CALM3	3
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	3/665	11/18722	0.00594562811416122	0.0344804804286829	KLF4/MYADM/WNK1	3
GO:0071679	commissural neuron axon guidance	3/665	11/18722	0.00594562811416122	0.0344804804286829	VEGFA/EPHB2/NRP1	3
GO:0075294	positive regulation by symbiont of entry into host	3/665	11/18722	0.00594562811416122	0.0344804804286829	HLA-DRB1/LGALS1/CD74	3
GO:2000644	regulation of receptor catabolic process	3/665	11/18722	0.00594562811416122	0.0344804804286829	APOE/DTX3L/ANXA2	3
GO:0009636	response to toxic substance	18/665	262/18722	0.00598998360805014	0.0346972243962811	NUPR1/APOE/SOD2/AHR/HBG1/CD36/GLRX/CLIC2/MT1X/ALOX5AP/FOS/CDKN1A/TXN/ESD/CYP1B1/TLR2/SCN9A/GPX1	18
GO:0051222	positive regulation of protein transport	20/665	303/18722	0.00604398404506656	0.0349692674085923	HLA-DRB1/TREM2/ADAM8/GLUL/DYNLL1/IRS2/ANG/RAC1/ITGAM/FLNA/HCLS1/EGFR/PLK3/KIF5B/CAMK1/OAZ1/TLR2/CD81/ATP2C1/PRNP	20
GO:0045646	regulation of erythrocyte differentiation	6/665	47/18722	0.00610705022379799	0.0352520785276144	ISG15/B2M/STAT1/ZFP36/MAFB/SPI1	6
GO:0061001	regulation of dendritic spine morphogenesis	6/665	47/18722	0.00610705022379799	0.0352520785276144	TANC2/PTEN/LRRK2/ABI3/CFL1/SIPA1L1	6
GO:0003012	muscle system process	27/665	452/18722	0.00614635468870474	0.0354377990752466	CXCR4/SULF2/SLC6A8/CALM1/KLF4/ALDOA/ERRFI1/GSN/HAMP/SCO2/CLIC2/ENO1/HMOX1/DOCK4/FLNA/KCNE1/RHOA/RGS2/LMNA/PTAFR/GATM/CALM3/KCNMA1/NR4A1/JARID2/SMAD7/MYL6	27
GO:0044262	cellular carbohydrate metabolic process	19/665	283/18722	0.00615454439211855	0.0354400682682885	NUPR1/DDIT4/HK2/FBP1/TPI1/IRS2/IDH1/PPP1CB/PPP1R3B/PTEN/B3GNT7/PTGES3/PTAFR/PHLDA2/PGAM1/PTK2B/IGF2/SCARB2/GALK1	19
GO:0001938	positive regulation of endothelial cell proliferation	10/665	111/18722	0.00616100985589563	0.0354400682682885	VEGFA/ECM1/ANG/HMOX1/TNFSF12/ACVRL1/IGF2/NR4A1/CXCL12/NRP1	10
GO:0002690	positive regulation of leukocyte chemotaxis	9/665	94/18722	0.0061888331123103	0.0355178990394714	VEGFA/CD74/CXCL8/C5AR1/RAC1/WNK1/SPI1/PTK2B/CXCL12	9
GO:1990830	cellular response to leukemia inhibitory factor	9/665	94/18722	0.0061888331123103	0.0355178990394714	HK2/KLF4/SNX10/SOCS3/NCL/CACYBP/TFRC/JARID2/SMAD7	9
GO:0003018	vascular process in circulatory system	18/665	263/18722	0.00622443455479241	0.0356810146912552	VEGFA/APOE/SLC1A3/ADM/SOD2/CD36/SLC38A2/SLC2A3/DOCK4/KLF2/RHOA/RGS2/EGFR/PLEC/ABCC3/KCNMA1/TFRC/GPX1	18
GO:0002260	lymphocyte homeostasis	7/665	62/18722	0.00624994867632607	0.035744815789805	TSC22D3/CD74/TNFSF13B/SKIL/TNFAIP3/SOS2/CAMLG	7
GO:0032757	positive regulation of interleukin-8 production	7/665	62/18722	0.00624994867632607	0.035744815789805	CD74/CLEC7A/MYD88/PYCARD/LAMTOR5/CD58/TLR2	7
GO:0001889	liver development	12/665	147/18722	0.0062581822100814	0.0357507650392006	SULF2/CEBPB/CSNK2B/HAMP/RAP1A/TNFAIP3/CITED2/HMOX1/ANXA1/EGFR/KRT18/JARID2	12
GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	8/665	78/18722	0.00639913139066664	0.0365139873841713	TREM2/GPNMB/ACP5/ERRFI1/TSPO/TNFAIP3/CLEC4A/IL27RA	8
GO:0032868	response to insulin	18/665	264/18722	0.00646630185051027	0.0368549543543991	STAT1/PKM/ADM/ERRFI1/RAB8A/IRS2/PIP4K2A/GRB2/PTEN/SOCS3/EGR1/INSIG2/RAB13/GCNT1/IGF2/TLR2/RAB31/CPEB2	18
GO:0002446	neutrophil mediated immunity	5/665	34/18722	0.00659905323107185	0.0373120529674939	MYD88/TREM1/ITGAM/PTAFR/SPI1	5
GO:0032743	positive regulation of interleukin-2 production	5/665	34/18722	0.00659905323107185	0.0373120529674939	CLEC7A/ANXA1/CD83/CD86/RIPK2	5
GO:0032770	positive regulation of monooxygenase activity	5/665	34/18722	0.00659905323107185	0.0373120529674939	APOE/CALM1/CALM3/PTK2B/PIK3CB	5
GO:0034383	low-density lipoprotein particle clearance	5/665	34/18722	0.00659905323107185	0.0373120529674939	TREM2/CD36/HMOX1/SOAT1/ANXA2	5
GO:0050869	negative regulation of B cell activation	5/665	34/18722	0.00659905323107185	0.0373120529674939	FCGR2B/CD300A/TNFAIP3/SAMSN1/TYROBP	5
GO:0070232	regulation of T cell apoptotic process	5/665	34/18722	0.00659905323107185	0.0373120529674939	TSC22D3/ADAM8/LGALS3/IL7R/DOCK8	5
GO:0098751	bone cell development	5/665	34/18722	0.00659905323107185	0.0373120529674939	PIP4K2A/ABI1/ANXA2/TYROBP/ZNF385A	5
GO:1903321	negative regulation of protein modification by small protein conjugation or removal	9/665	95/18722	0.00662746334350176	0.0373876195427965	ISG15/TSPO/N4BP1/TNFAIP3/DTX3L/SQSTM1/IVNS1ABP/CAMLG/SMAD7	9
GO:1990823	response to leukemia inhibitory factor	9/665	95/18722	0.00662746334350176	0.0373876195427965	HK2/KLF4/SNX10/SOCS3/NCL/CACYBP/TFRC/JARID2/SMAD7	9
GO:0015918	sterol transport	11/665	130/18722	0.0066674583965004	0.037570598900915	TREM2/APOE/APOC1/NFKBIA/TSPO/CD36/PIP4K2A/MSR1/OSBPL1A/SOAT1/ANXA2	11
GO:0002715	regulation of natural killer cell mediated immunity	6/665	48/18722	0.00677475827021164	0.0380458176304541	HLA-A/HLA-B/HLA-F/CADM1/LAG3/HLA-E	6
GO:0048146	positive regulation of fibroblast proliferation	6/665	48/18722	0.00677475827021164	0.0380458176304541	CD74/S100A6/MIF/CDKN1A/ANXA2/FN1	6
GO:0090199	regulation of release of cytochrome c from mitochondria	6/665	48/18722	0.00677475827021164	0.0380458176304541	BNIP3/PYCARD/FAM162A/LMNA/PLAUR/GPX1	6
GO:0042391	regulation of membrane potential	26/665	434/18722	0.00683778108402102	0.0383564017918561	TREM2/YWHAH/JUN/CALM1/IFI6/GNAQ/SOD2/BNIP3L/KCNQ3/TSPO/CD36/GLRX/BNIP3/CLIC1/PTEN/FLNA/KCNE1/GABRB2/LRRK2/CALM3/KIF5B/KCNAB2/PTK2B/KCNMA1/SCN9A/SMAD7	26
GO:0032069	regulation of nuclease activity	4/665	22/18722	0.0069281231067459	0.0386885076859855	OAS2/OAS1/OAS3/OASL	4
GO:0060713	labyrinthine layer morphogenesis	4/665	22/18722	0.0069281231067459	0.0386885076859855	ADM/ST14/GRB2/SOCS3	4
GO:0061042	vascular wound healing	4/665	22/18722	0.0069281231067459	0.0386885076859855	CXCR4/VEGFA/ALOX5/TNFAIP3	4
GO:1900120	regulation of receptor binding	4/665	22/18722	0.0069281231067459	0.0386885076859855	B2M/PHLDA2/ANXA2/NRP1	4
GO:0051495	positive regulation of cytoskeleton organization	16/665	226/18722	0.00701749640189109	0.0391436106817045	S100A10/GSN/GMFG/ARPC4/MAPRE1/PYCARD/GRB2/RAC1/FLNA/RHOA/HCLS1/RHOC/PTK2B/HAX1/IQGAP2/NRP1	16
GO:1901655	cellular response to ketone	9/665	96/18722	0.00708955937950587	0.0395012445248253	DDIT4/KLF4/ERRFI1/AHR/MSN/KLF2/EGFR/KLF9/EIF4E	9
GO:0032412	regulation of ion transmembrane transporter activity	18/665	267/18722	0.0072380986911801	0.0402837071614391	TREM2/YWHAH/CALM1/FXYD5/GLRX/CLIC2/PTEN/KCNE1/IFNGR2/PTAFR/AHNAK/WNK1/CALM3/KIF5B/C4orf3/PTK2B/EPHB2/PRNP	18
GO:0061008	hepaticobiliary system development	12/665	150/18722	0.00731975587501284	0.0406926025713801	SULF2/CEBPB/CSNK2B/HAMP/RAP1A/TNFAIP3/CITED2/HMOX1/ANXA1/EGFR/KRT18/JARID2	12
GO:1901800	positive regulation of proteasomal protein catabolic process	10/665	114/18722	0.00740596693711748	0.0411247475142932	NUPR1/TREM2/DAB2/SUMO2/TRIB1/RBX1/LRRK2/PSMC6/PLK3/SMAD7	10
GO:0001885	endothelial cell development	7/665	64/18722	0.00743058818266304	0.0411247475142932	VEGFA/MYADM/RAP1A/MYD88/MSN/RAPGEF1/GPX1	7
GO:0045670	regulation of osteoclast differentiation	7/665	64/18722	0.00743058818266304	0.0411247475142932	TREM2/CEBPB/KLF10/MAFB/RASSF2/FOS/TYROBP	7
GO:0048247	lymphocyte chemotaxis	7/665	64/18722	0.00743058818266304	0.0411247475142932	GPR183/ADAM8/CXCL16/PLEC/WNK1/PTK2B/CCL13	7
GO:0001570	vasculogenesis	8/665	80/18722	0.0074400870017343	0.0411315154600884	VEGFA/ADM/RAP1A/JUNB/CITED2/RIN2/TIPARP/SETD2	8
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	5/665	35/18722	0.0074785579748234	0.0411538167622628	VEGFA/HMOX1/ANXA1/MAP3K3/NRP1	5
GO:0010823	negative regulation of mitochondrion organization	6/665	49/18722	0.00749380365590499	0.0411538167622628	TSPO/BNIP3/LMNA/VAT1/TFRC/GPX1	6
GO:0014075	response to amine	6/665	49/18722	0.00749380365590499	0.0411538167622628	CALM1/NR4A2/RRM2B/RGS2/CALM3/NR4A1	6
GO:0050832	defense response to fungus	6/665	49/18722	0.00749380365590499	0.0411538167622628	CLEC7A/HAMP/GAPDH/COTL1/S100A8/SPI1	6
GO:0070849	response to epidermal growth factor	6/665	49/18722	0.00749380365590499	0.0411538167622628	ZFP36L2/ERRFI1/ZFP36/PTPN12/EGFR/NCL	6
GO:1990928	response to amino acid starvation	6/665	49/18722	0.00749380365590499	0.0411538167622628	EIF2AK2/ATF3/SLC38A2/EIF4EBP1/RRAGD/CDKN1A	6
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	9/665	97/18722	0.00757590978511645	0.0415587987108485	IFI6/LGALS3/PEA15/TNFAIP3/MCL1/HMOX1/LMNA/GPX1/NRP1	9
GO:0006887	exocytosis	22/665	352/18722	0.00768720100528897	0.0419342338186106	FCGR2B/CD300A/CALM1/MYO1G/RAB8A/HLA-F/RAP1A/HMOX1/ANXA1/RALA/ITGAM/PTAFR/LRRK2/SDCBP/LIN7C/CALM3/STX3/SPI1/TMEM167A/RAB13/SYNGR2/RAB31	22
GO:0043129	surfactant homeostasis	3/665	12/18722	0.00772028650785286	0.0419342338186106	VEGFA/CTSH/OAS1	3
GO:0043380	regulation of memory T cell differentiation	3/665	12/18722	0.00772028650785286	0.0419342338186106	HLA-DRB1/HLA-DRA/FGL2	3
GO:0060009	Sertoli cell development	3/665	12/18722	0.00772028650785286	0.0419342338186106	HSD17B4/FLNA/RAB13	3
GO:0061620	glycolytic process through glucose-6-phosphate	3/665	12/18722	0.00772028650785286	0.0419342338186106	HK2/ENO1/GALK1	3
GO:0070586	cell-cell adhesion involved in gastrulation	3/665	12/18722	0.00772028650785286	0.0419342338186106	KLF4/MYADM/WNK1	3
GO:0140289	protein mono-ADP-ribosylation	3/665	12/18722	0.00772028650785286	0.0419342338186106	PARP9/PARP12/TIPARP	3
GO:1902950	regulation of dendritic spine maintenance	3/665	12/18722	0.00772028650785286	0.0419342338186106	FCGR2B/APOE/PRNP	3
GO:2001214	positive regulation of vasculogenesis	3/665	12/18722	0.00772028650785286	0.0419342338186106	ADM/RAP1A/RIN2	3
GO:0045444	fat cell differentiation	16/665	229/18722	0.00792369712750066	0.0429921121437536	ATF5/ZFP36L2/ALOX5/KLF4/CEBPB/ERO1A/NR4A2/ZFP36/PSMB8/MAFB/BNIP3/RGS2/ZNF385A/CCDC85B/NR4A1/GPX1	16
GO:0006163	purine nucleotide metabolic process	24/665	396/18722	0.00797590057187104	0.0432281634047973	NUPR1/LDHA/TREM2/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/ACSL1/HSD17B4/TPI1/PAPSS1/GAPDH/ENO1/RHOA/PAPSS2/GPI/LRRK2/ENO2/PGAM1/GUK1/ABHD14B/GALK1	24
GO:0043489	RNA stabilization	7/665	65/18722	0.0080791630343188	0.0436890406757295	SLC11A1/YBX3/ZFP36/MYD88/YBX1/HNRNPA0/ELAVL1	7
GO:0070301	cellular response to hydrogen peroxide	9/665	98/18722	0.00808730732830406	0.0436890406757295	KLF4/BNIP3/TNFAIP3/ANXA1/KLF2/RHOB/LRRK2/TXN/CYP1B1	9
GO:1902882	regulation of response to oxidative stress	9/665	98/18722	0.00808730732830406	0.0436890406757295	TREM2/PAGE4/ALOX5/SOD2/CD36/MCL1/LRRK2/TXN/GPX1	9
GO:0006929	substrate-dependent cell migration	4/665	23/18722	0.00815500795506459	0.0438640579401202	ADAM8/SDCBP/FN1/NRP1	4
GO:0035994	response to muscle stretch	4/665	23/18722	0.00815500795506459	0.0438640579401202	NFKBIA/GSN/FOS/GPI	4
GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	4/665	23/18722	0.00815500795506459	0.0438640579401202	TREM2/CAPN2/CAMK1/TYROBP	4
GO:0072677	eosinophil migration	4/665	23/18722	0.00815500795506459	0.0438640579401202	CD300A/ADAM8/LGALS3/CCL13	4
GO:0007623	circadian rhythm	15/665	210/18722	0.00820636540148227	0.0440925795085047	ATF5/JUND/JUN/GNAQ/AHR/BHLHE40/NFIL3/KLF10/NAMPT/PPP1CB/PTEN/EGR1/EGFR/KLF9/PER1	15
GO:0002639	positive regulation of immunoglobulin production	6/665	50/18722	0.00826629881823968	0.0443187757569053	GPI/CD86/HLA-E/TFRC/EPHB2/PHB	6
GO:0019083	viral transcription	6/665	50/18722	0.00826629881823968	0.0443187757569053	JUN/IFITM3/ZFP36/LARP7/MDFIC/RSF1	6
GO:1990748	cellular detoxification	10/665	116/18722	0.00833817233767673	0.0446559445239799	APOE/SOD2/HBG1/CD36/GLRX/CLIC2/ALOX5AP/TXN/ESD/GPX1	10
GO:0050821	protein stabilization	14/665	191/18722	0.00842076460423648	0.0449402855586448	GNAQ/UBE2B/GAPDH/RASSF2/PTEN/GOLGA7/FLNA/PTGES3/GRN/TYROBP/IFI30/PHB/CAMLG/SMAD7	14
GO:0030224	monocyte differentiation	5/665	36/18722	0.0084364761420957	0.0449402855586448	HLA-DRB1/VEGFA/CD74/JUN/IRF7	5
GO:0051385	response to mineralocorticoid	5/665	36/18722	0.0084364761420957	0.0449402855586448	CALM1/FOSB/FOS/CALM3/CDKN1A	5
GO:0060338	regulation of type I interferon-mediated signaling pathway	5/665	36/18722	0.0084364761420957	0.0449402855586448	ISG15/OAS1/OAS3/IRF7/USP18	5
GO:0070873	regulation of glycogen metabolic process	5/665	36/18722	0.0084364761420957	0.0449402855586448	IRS2/PPP1CB/PPP1R3B/PHLDA2/IGF2	5
GO:0002312	B cell activation involved in immune response	8/665	82/18722	0.0086036626949442	0.0457818025630329	FCGR2B/LGALS1/GPR183/IRF8/IL27RA/SPI1/PTK2B/TFRC	8
GO:0000045	autophagosome assembly	9/665	99/18722	0.00862454811885362	0.0458438547066337	NUPR1/PIP4K2A/MAP1LC3B/GABARAPL2/WDR45B/LRRK2/ATG3/WIPI2/RNF5	9
GO:0030193	regulation of blood coagulation	7/665	66/18722	0.00876849436092757	0.0465095165142049	CD9/APOE/SERPING1/CD36/PLAU/ANXA2/EPHB2	7
GO:0050918	positive chemotaxis	7/665	66/18722	0.00876849436092757	0.0465095165142049	VEGFA/GPNMB/CXCL8/MIF/LGALS3/CXCL12/NRP1	7
GO:0030301	cholesterol transport	10/665	117/18722	0.00883681856359843	0.046772085475063	TREM2/APOE/APOC1/NFKBIA/TSPO/CD36/PIP4K2A/MSR1/SOAT1/ANXA2	10
GO:1903828	negative regulation of cellular protein localization	10/665	117/18722	0.00883681856359843	0.046772085475063	DAB2/CD36/GBP1/KCNE1/LRRK2/SPI1/TXN/ABI3/MDFIC/TMEM59	10
GO:0032271	regulation of protein polymerization	16/665	232/18722	0.00892125454738678	0.0471687607452259	CAPG/MYADM/GSN/GMFG/ARPC4/MAPRE1/PYCARD/GRB2/RAC1/RHOA/HCLS1/COTL1/TMSB10/PTK2B/HAX1/IQGAP2	16
GO:1904062	regulation of cation transmembrane transport	22/665	357/18722	0.00898668928137283	0.0474642356306301	TREM2/YWHAH/CALM1/FXYD5/GLRX/HAMP/CLIC2/PTEN/FLNA/KCNE1/RGS2/IFNGR2/AHNAK/WNK1/CALM3/KIF5B/C4orf3/KCNAB2/PTK2B/DIAPH1/EPHB2/PRNP	22
GO:0002768	immune response-regulating cell surface receptor signaling pathway	20/665	315/18722	0.00910928849304387	0.0480606834505605	FCGR2B/HLA-DRB1/HLA-DQB1/FPR3/HLA-A/HLA-DPB1/CD300A/MYO1G/PLSCR1/CLEC7A/C5AR1/RAP1A/LGALS3/GBP1/NFKBIZ/WNK1/TYROBP/CD81/RIPK2/PRNP	20
GO:0045807	positive regulation of endocytosis	9/665	100/18722	0.00918843073540811	0.0484268300689059	TREM2/VEGFA/B2M/APOE/DAB2/CD36/LRRK2/ANXA2/RAB31	9
GO:0045727	positive regulation of translation	11/665	136/18722	0.00924609397227193	0.0486276053356524	VIM/PKM/YBX3/PPP1R15A/RPS27L/CNBP/RHOA/PTAFR/PTK2B/TOB1/ELAVL1	11
GO:1903305	regulation of regulated secretory pathway	11/665	136/18722	0.00924609397227193	0.0486276053356524	FCGR2B/CD300A/CALM1/HLA-F/RAP1A/HMOX1/ITGAM/PTAFR/LRRK2/CALM3/SPI1	11
GO:0001659	temperature homeostasis	13/665	174/18722	0.00936076212915812	0.0491786340189385	CXCR4/VEGFA/SCD/CEBPB/ACSL1/CD36/EGR1/ARRDC3/GATM/G0S2/TLE3/RB1/GPX1	13
GO:0006606	protein import into nucleus	12/665	155/18722	0.00939824517819903	0.0493234197842124	TXNIP/NFKBIA/CD36/NUP58/FLNA/HCLS1/LMNA/LRRK2/KPNA3/CDKN1A/MDFIC/ELAVL1	12
GO:0006879	cellular iron ion homeostasis	7/665	67/18722	0.00950001471566255	0.0493455675664216	SLC11A1/FTH1/HAMP/HMOX1/ATP6V1G1/FTL/TFRC	7
GO:0042130	negative regulation of T cell proliferation	7/665	67/18722	0.00950001471566255	0.0493455675664216	HLA-DRB1/IL4I1/GPNMB/CEBPB/TNFRSF14/CD86/PRNP	7
GO:0070527	platelet aggregation	7/665	67/18722	0.00950001471566255	0.0493455675664216	CD9/CLIC1/PDPN/FLNA/MYL12A/PIK3CB/FN1	7
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	4/665	24/18722	0.00951605032246758	0.0493455675664216	CD300A/MYD88/IRF7/TLR2	4
GO:0006213	pyrimidine nucleoside metabolic process	4/665	24/18722	0.00951605032246758	0.0493455675664216	NT5C3A/TYMP/UPP1/ERH	4
GO:0033032	regulation of myeloid cell apoptotic process	4/665	24/18722	0.00951605032246758	0.0493455675664216	IRF7/PTEN/ANXA1/PIK3CB	4
GO:0035458	cellular response to interferon-beta	4/665	24/18722	0.00951605032246758	0.0493455675664216	CAPN2/STAT1/OAS1/IFITM2	4
GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	4/665	24/18722	0.00951605032246758	0.0493455675664216	VEGFA/CEBPB/ATF3/KLF2	4
GO:0045649	regulation of macrophage differentiation	4/665	24/18722	0.00951605032246758	0.0493455675664216	C1QC/HCLS1/TRIB1/RB1	4
GO:0090023	positive regulation of neutrophil chemotaxis	4/665	24/18722	0.00951605032246758	0.0493455675664216	CD74/CXCL8/C5AR1/RAC1	4
GO:1903077	negative regulation of protein localization to plasma membrane	4/665	24/18722	0.00951605032246758	0.0493455675664216	DAB2/GBP1/ABI3/TMEM59	4
GO:0034754	cellular hormone metabolic process	11/665	137/18722	0.00974184197571506	0.0493455675664216	IL4I1/ADM/HSD17B4/TSPO/HSD17B11/EGR1/DHRS3/RBP1/CYP1B1/TIPARP/HSD17B1	11
GO:0050714	positive regulation of protein secretion	11/665	137/18722	0.00974184197571506	0.0493455675664216	HLA-DRB1/TREM2/ADAM8/GLUL/DYNLL1/IRS2/ANG/RAC1/EGFR/KIF5B/TLR2	11
GO:0002551	mast cell chemotaxis	3/665	13/18722	0.00977452710791786	0.0493455675664216	VEGFA/RIN3/RAC1	3
GO:0010635	regulation of mitochondrial fusion	3/665	13/18722	0.00977452710791786	0.0493455675664216	BNIP3/VAT1/TFRC	3
GO:0014745	negative regulation of muscle adaptation	3/665	13/18722	0.00977452710791786	0.0493455675664216	KLF4/ERRFI1/LMNA	3
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	3/665	13/18722	0.00977452710791786	0.0493455675664216	CARD16/TNFAIP3/TRIB1	3
GO:0032429	regulation of phospholipase A2 activity	3/665	13/18722	0.00977452710791786	0.0493455675664216	ANG/ANXA1/EGFR	3
GO:0034112	positive regulation of homotypic cell-cell adhesion	3/665	13/18722	0.00977452710791786	0.0493455675664216	LGALS1/PDPN/PLAUR	3
GO:0035745	T-helper 2 cell cytokine production	3/665	13/18722	0.00977452710791786	0.0493455675664216	RSAD2/NLRP3/CD81	3
GO:0036462	TRAIL-activated apoptotic signaling pathway	3/665	13/18722	0.00977452710791786	0.0493455675664216	ATF3/PTEN/SPI1	3
GO:0043379	memory T cell differentiation	3/665	13/18722	0.00977452710791786	0.0493455675664216	HLA-DRB1/HLA-DRA/FGL2	3
GO:0044090	positive regulation of vacuole organization	3/665	13/18722	0.00977452710791786	0.0493455675664216	PIP4K2A/GRN/ANXA2	3
GO:0048266	behavioral response to pain	3/665	13/18722	0.00977452710791786	0.0493455675664216	CAPN2/TSPO/SCN9A	3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	3/665	13/18722	0.00977452710791786	0.0493455675664216	CALM1/CLIC2/CALM3	3
GO:0060100	positive regulation of phagocytosis, engulfment	3/665	13/18722	0.00977452710791786	0.0493455675664216	TREM2/CD36/RAB31	3
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	3/665	13/18722	0.00977452710791786	0.0493455675664216	VEGFA/CITED2/EGR1	3
GO:0061469	regulation of type B pancreatic cell proliferation	3/665	13/18722	0.00977452710791786	0.0493455675664216	NUPR1/ERRFI1/NR4A1	3
GO:0061615	glycolytic process through fructose-6-phosphate	3/665	13/18722	0.00977452710791786	0.0493455675664216	HK2/ENO1/GALK1	3
GO:0070486	leukocyte aggregation	3/665	13/18722	0.00977452710791786	0.0493455675664216	CD44/MSN/S100A8	3
GO:0071801	regulation of podosome assembly	3/665	13/18722	0.00977452710791786	0.0493455675664216	GSN/MSN/RHOA	3
GO:1900272	negative regulation of long-term synaptic potentiation	3/665	13/18722	0.00977452710791786	0.0493455675664216	APOE/TYROBP/PRNP	3
GO:1902947	regulation of tau-protein kinase activity	3/665	13/18722	0.00977452710791786	0.0493455675664216	C5AR1/EGR1/RB1	3
GO:1905155	positive regulation of membrane invagination	3/665	13/18722	0.00977452710791786	0.0493455675664216	TREM2/CD36/RAB31	3
GO:1905907	negative regulation of amyloid fibril formation	3/665	13/18722	0.00977452710791786	0.0493455675664216	TREM2/APOE/PFDN6	3
GO:2000551	regulation of T-helper 2 cell cytokine production	3/665	13/18722	0.00977452710791786	0.0493455675664216	RSAD2/NLRP3/CD81	3
GO:2001198	regulation of dendritic cell differentiation	3/665	13/18722	0.00977452710791786	0.0493455675664216	FCGR2B/HLA-B/CEBPB	3
GO:0098869	cellular oxidant detoxification	9/665	101/18722	0.0097797553426409	0.0493455675664216	APOE/SOD2/HBG1/CD36/GLRX/CLIC2/ALOX5AP/TXN/GPX1	9
GO:0098586	cellular response to virus	8/665	84/18722	0.00989823225394444	0.0498124355299789	OAS1/OAS3/IFIH1/IFI6/IRF7/DDX60/OASL/PHB	8
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	8/665	84/18722	0.00989823225394444	0.0498124355299789	GPNMB/KLF4/RPS27L/PTEN/RPA2/PLK3/CDKN1A/RB1	8
GO:0030282	bone mineralization	10/665	119/18722	0.00990235136893746	0.0498124355299789	ISG15/SRGN/GPNMB/ALOX5/SNX10/ECM1/KLF10/FBN2/FBXL15/PTK2B	10
GO:0043277	apoptotic cell clearance	6/665	52/18722	0.00997996920830472	0.0501521202884474	TREM2/MERTK/CD36/RAC1/ANXA1/TYROBP	6
GO:0043534	blood vessel endothelial cell migration	13/665	176/18722	0.010244997972964	0.0514274766546485	VEGFA/APOE/KLF4/CSNK2B/HMOX1/ANXA1/RHOA/MAP3K3/ACVRL1/PTK2B/NR4A1/GPX1/NRP1	13
GO:0031640	killing of cells of other organism	7/665	68/18722	0.0102751477501139	0.0514274766546485	LYZ/CLEC7A/HAMP/MYD88/GAPDH/TREM1/CCL13	7
GO:0042267	natural killer cell mediated cytotoxicity	7/665	68/18722	0.0102751477501139	0.0514274766546485	HLA-A/HLA-B/HLA-F/CADM1/LAG3/KIF5B/HLA-E	7
GO:1900046	regulation of hemostasis	7/665	68/18722	0.0102751477501139	0.0514274766546485	CD9/APOE/SERPING1/CD36/PLAU/ANXA2/EPHB2	7
GO:1904951	positive regulation of establishment of protein localization	20/665	319/18722	0.0103731866883248	0.0517606157689941	HLA-DRB1/TREM2/ADAM8/GLUL/DYNLL1/IRS2/ANG/RAC1/ITGAM/FLNA/HCLS1/EGFR/PLK3/KIF5B/CAMK1/OAZ1/TLR2/CD81/ATP2C1/PRNP	20
GO:0032677	regulation of interleukin-8 production	9/665	102/18722	0.0103993228002764	0.0517606157689941	CD74/KLF4/CLEC7A/MYD88/PYCARD/ANXA1/LAMTOR5/CD58/TLR2	9
GO:1902106	negative regulation of leukocyte differentiation	9/665	102/18722	0.0103993228002764	0.0517606157689941	FCGR2B/CD74/FGL2/MAFB/C1QC/ANXA1/LAG3/TRIB1/SMAD7	9
GO:1904063	negative regulation of cation transmembrane transport	9/665	102/18722	0.0103993228002764	0.0517606157689941	CALM1/HAMP/CLIC2/PTEN/KCNE1/RGS2/CALM3/C4orf3/EPHB2	9
GO:0010720	positive regulation of cell development	19/665	298/18722	0.0104038106528296	0.0517606157689941	CXCR4/VEGFA/LIMS1/CLEC7A/S100A10/MYADM/TSPO/SKIL/RAC1/FLNA/TRIB1/EGFR/TYROBP/EPHB2/FN1/TLR2/CXCL12/SMAD7/NRP1	19
GO:0000209	protein polyubiquitination	16/665	236/18722	0.0104041962078924	0.0517606157689941	UBE2L6/IFI27/TRIM22/NMI/UBE2B/TNFAIP3/SMURF2/DTX3L/SPOP/RBX1/ANAPC13/UBE2D2/RNF187/RNF5/UBE2D1/UBE2Q2	16
GO:0006006	glucose metabolic process	14/665	196/18722	0.0104363029246469	0.0518684255354952	OAS1/HK2/PGK1/FBP1/ATF3/TPI1/IRS2/GAPDH/PPP1CB/ENO1/PPP1R3B/GPI/PHLDA2/IGF2	14
GO:0032411	positive regulation of transporter activity	10/665	120/18722	0.0104705055516847	0.0519864261657072	TREM2/SGK1/CALM1/GLRX/IFNGR2/PTAFR/WNK1/CALM3/KIF5B/EPHB2	10
GO:0097006	regulation of plasma lipoprotein particle levels	8/665	85/18722	0.0105972535375266	0.0523702853764159	TREM2/APOE/APOC1/CD36/MSR1/HMOX1/SOAT1/ANXA2	8
GO:0008210	estrogen metabolic process	5/665	38/18722	0.0106005044444013	0.0523702853764159	HSD17B4/HSD17B11/CYP1B1/TIPARP/HSD17B1	5
GO:0010742	macrophage derived foam cell differentiation	5/665	38/18722	0.0106005044444013	0.0523702853764159	NFKBIA/STAT1/CD36/MSR1/SOAT1	5
GO:0072538	T-helper 17 type immune response	5/665	38/18722	0.0106005044444013	0.0523702853764159	CLEC7A/NFKBIZ/IL27RA/PHB/SMAD7	5
GO:0090077	foam cell differentiation	5/665	38/18722	0.0106005044444013	0.0523702853764159	NFKBIA/STAT1/CD36/MSR1/SOAT1	5
GO:0022898	regulation of transmembrane transporter activity	18/665	278/18722	0.0107287067216234	0.0529510152993727	TREM2/YWHAH/CALM1/FXYD5/GLRX/CLIC2/PTEN/KCNE1/IFNGR2/PTAFR/AHNAK/WNK1/CALM3/KIF5B/C4orf3/PTK2B/EPHB2/PRNP	18
GO:0008347	glial cell migration	6/665	53/18722	0.0109252354908965	0.053814093547825	TREM2/GPR183/CD9/TSPO/MMP14/HEXB	6
GO:0045806	negative regulation of endocytosis	6/665	53/18722	0.0109252354908965	0.053814093547825	CD300A/APOC1/LGALS3/RIN3/RAC1/SDCBP	6
GO:0010954	positive regulation of protein processing	4/665	25/18722	0.0110165390641724	0.0539962516261706	ADAM8/GSN/ENO1/MMP14	4
GO:0031579	membrane raft organization	4/665	25/18722	0.0110165390641724	0.0539962516261706	S100A10/MYADM/GSN/ANXA2	4
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	4/665	25/18722	0.0110165390641724	0.0539962516261706	CARD16/CD36/TNFAIP3/TRIB1	4
GO:0035902	response to immobilization stress	4/665	25/18722	0.0110165390641724	0.0539962516261706	SOD2/FOS/GPI/PTK2B	4
GO:2000316	regulation of T-helper 17 type immune response	4/665	25/18722	0.0110165390641724	0.0539962516261706	CLEC7A/NFKBIZ/IL27RA/SMAD7	4
GO:0032637	interleukin-8 production	9/665	103/18722	0.011047933765673	0.0540435342671209	CD74/KLF4/CLEC7A/MYD88/PYCARD/ANXA1/LAMTOR5/CD58/TLR2	9
GO:1905037	autophagosome organization	9/665	103/18722	0.011047933765673	0.0540435342671209	NUPR1/PIP4K2A/MAP1LC3B/GABARAPL2/WDR45B/LRRK2/ATG3/WIPI2/RNF5	9
GO:0042177	negative regulation of protein catabolic process	10/665	121/18722	0.0110630987990115	0.0540645044553462	TIMP1/N4BP1/GABARAPL2/FLNA/EGFR/SDCBP/CTSA/ANXA2/PHB/CAMLG	10
GO:0016050	vesicle organization	19/665	300/18722	0.011114806665886	0.0542638400092862	SRGN/S100A10/SNX10/SAMD9/RAB8A/PIP4K2A/RAB20/BLOC1S1/ANXA1/BLOC1S2/SDCBP/KIF5B/STX3/RAB13/SQSTM1/ANXA2/SCARB2/VTA1/CHMP5	19
GO:0060761	negative regulation of response to cytokine stimulus	8/665	86/18722	0.0113321538032639	0.0552706618274993	ISG15/TREM2/OAS1/OAS3/KLF4/CARD16/ECM1/USP18	8
GO:0045927	positive regulation of growth	17/665	259/18722	0.0114039270325942	0.0555661934823462	CXCR4/VEGFA/YBX3/CXCL16/HAMP/RHOA/EGFR/SDCBP/S100A8/MMP14/PTK2B/IGF2/FN1/AGRN/CXCL12/SMAD7/NRP1	17
GO:0006913	nucleocytoplasmic transport	19/665	301/18722	0.0114845499166935	0.0558495235674822	MX2/IFI27/TXNIP/NFKBIA/SSB/CD36/NUP58/FLNA/HCLS1/LMNA/LRRK2/KPNA3/CDKN1A/TXN/CAMK1/HNRNPA1/MDFIC/ELAVL1/SETD2	19
GO:0051169	nuclear transport	19/665	301/18722	0.0114845499166935	0.0558495235674822	MX2/IFI27/TXNIP/NFKBIA/SSB/CD36/NUP58/FLNA/HCLS1/LMNA/LRRK2/KPNA3/CDKN1A/TXN/CAMK1/HNRNPA1/MDFIC/ELAVL1/SETD2	19
GO:0001936	regulation of endothelial cell proliferation	13/665	179/18722	0.0116918621620169	0.05680210649582	VEGFA/APOE/STAT1/ALOX5/ECM1/ANG/HMOX1/TNFSF12/ACVRL1/IGF2/NR4A1/CXCL12/NRP1	13
GO:0002701	negative regulation of production of molecular mediator of immune response	5/665	39/18722	0.0118128318131312	0.0572220020577603	FCGR2B/HLA-F/BST2/HMOX1/SMAD7	5
GO:0046621	negative regulation of organ growth	5/665	39/18722	0.0118128318131312	0.0572220020577603	CGA/CITED2/PTEN/RGS2/JARID2	5
GO:0071548	response to dexamethasone	5/665	39/18722	0.0118128318131312	0.0572220020577603	DDIT4/ERRFI1/EGFR/PTAFR/EIF4E	5
GO:0006968	cellular defense response	6/665	54/18722	0.0119321241663324	0.057687659719234	LSP1/LGALS3BP/C5AR1/NCF1/PTK2B/TYROBP	6
GO:0016241	regulation of macroautophagy	11/665	141/18722	0.0119321758936363	0.057687659719234	NUPR1/BNIP3L/PIP4K2A/GAPDH/BNIP3/HMOX1/ATP6V1G1/LRRK2/CAPNS1/ATP6V1B2/RIPK2	11
GO:0045123	cellular extravasation	7/665	70/18722	0.0119618867074532	0.0577750990632091	ADAM8/JAML/PTAFR/IL27RA/SELPLG/GCNT1/CXCL12	7
GO:0002475	antigen processing and presentation via MHC class Ib	3/665	14/18722	0.0121163627894414	0.0580697425877758	B2M/HLA-F/HLA-E	3
GO:0034616	response to laminar fluid shear stress	3/665	14/18722	0.0121163627894414	0.0580697425877758	KLF4/KLF2/SMAD7	3
GO:0045820	negative regulation of glycolytic process	3/665	14/18722	0.0121163627894414	0.0580697425877758	NUPR1/DDIT4/FBP1	3
GO:0048875	chemical homeostasis within a tissue	3/665	14/18722	0.0121163627894414	0.0580697425877758	VEGFA/CTSH/OAS1	3
GO:0050930	induction of positive chemotaxis	3/665	14/18722	0.0121163627894414	0.0580697425877758	VEGFA/CXCL8/CXCL12	3
GO:0061043	regulation of vascular wound healing	3/665	14/18722	0.0121163627894414	0.0580697425877758	CXCR4/ALOX5/TNFAIP3	3
GO:0090715	immunological memory formation process	3/665	14/18722	0.0121163627894414	0.0580697425877758	HLA-DRB1/HLA-DRA/FGL2	3
GO:0097531	mast cell migration	3/665	14/18722	0.0121163627894414	0.0580697425877758	VEGFA/RIN3/RAC1	3
GO:0002064	epithelial cell development	15/665	220/18722	0.0122494439928665	0.058650998694168	VIM/CXCR4/VEGFA/MYADM/HSD17B4/ST14/RAP1A/MYD88/MSN/RAPGEF1/FLNA/PLEC/CDKN1A/RAB13/GPX1	15
GO:0030168	platelet activation	10/665	123/18722	0.0123241468995768	0.0589518865167438	CD9/APOE/PLSCR1/MERTK/CLIC1/PDPN/FLNA/MYL12A/PIK3CB/FN1	10
GO:0000041	transition metal ion transport	9/665	105/18722	0.012435482421397	0.0594272573407147	SLC11A1/B2M/SLC25A37/FTH1/HAMP/FTL/TCN2/TFRC/ATP2C1	9
GO:2000045	regulation of G1/S transition of mitotic cell cycle	11/665	142/18722	0.0125341886976967	0.059841419623009	GPNMB/KLF4/PSME2/RPS27L/PTEN/ANXA1/EGFR/RPA2/PLK3/CDKN1A/RB1	11
GO:0002418	immune response to tumor cell	4/665	26/18722	0.0126613590246783	0.060159612191827	HLA-DRB1/IL4I1/HLA-A/AHR	4
GO:0034114	regulation of heterotypic cell-cell adhesion	4/665	26/18722	0.0126613590246783	0.060159612191827	KLF4/MYADM/CD44/WNK1	4
GO:0045672	positive regulation of osteoclast differentiation	4/665	26/18722	0.0126613590246783	0.060159612191827	TREM2/KLF10/FOS/TYROBP	4
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	4/665	26/18722	0.0126613590246783	0.060159612191827	HLA-F/CADM1/LAG3/HLA-E	4
GO:1904376	negative regulation of protein localization to cell periphery	4/665	26/18722	0.0126613590246783	0.060159612191827	DAB2/GBP1/ABI3/TMEM59	4
GO:0002228	natural killer cell mediated immunity	7/665	71/18722	0.0128762726877201	0.0610057914756616	HLA-A/HLA-B/HLA-F/CADM1/LAG3/KIF5B/HLA-E	7
GO:0033555	multicellular organismal response to stress	7/665	71/18722	0.0128762726877201	0.0610057914756616	APOE/CAPN2/NR4A2/TSPO/PTEN/EIF4E/SCN9A	7
GO:0050818	regulation of coagulation	7/665	71/18722	0.0128762726877201	0.0610057914756616	CD9/APOE/SERPING1/CD36/PLAU/ANXA2/EPHB2	7
GO:0010508	positive regulation of autophagy	10/665	124/18722	0.012993873037066	0.0613702273618759	TRIM22/BNIP3L/PIP4K2A/BNIP3/HMOX1/LRRK2/PLK3/PIK3CB/TMEM59/RIPK2	10
GO:0097237	cellular response to toxic substance	10/665	124/18722	0.012993873037066	0.0613702273618759	APOE/SOD2/HBG1/CD36/GLRX/CLIC2/ALOX5AP/TXN/ESD/GPX1	10
GO:0000768	syncytium formation by plasma membrane fusion	6/665	55/18722	0.0130025853947797	0.0613702273618759	TREM2/CD9/CAPN2/CAMK1/TYROBP/CD81	6
GO:0140253	cell-cell fusion	6/665	55/18722	0.0130025853947797	0.0613702273618759	TREM2/CD9/CAPN2/CAMK1/TYROBP/CD81	6
GO:0043001	Golgi to plasma membrane protein transport	5/665	40/18722	0.0131159894132385	0.0617296092649576	VAMP5/GOLGA7/KRT18/RAB31/ATP2C1	5
GO:0044275	cellular carbohydrate catabolic process	5/665	40/18722	0.0131159894132385	0.0617296092649576	TPI1/PPP1CB/PPP1R3B/PGAM1/SCARB2	5
GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	5/665	40/18722	0.0131159894132385	0.0617296092649576	ALOX5/KLF4/RHOA/PTAFR/CXCL12	5
GO:0006906	vesicle fusion	9/665	106/18722	0.0131760122816859	0.0618364315769396	SAMD9/RAB8A/PIP4K2A/RAB20/ANXA1/KIF5B/STX3/RAB13/ANXA2	9
GO:0046620	regulation of organ growth	9/665	106/18722	0.0131760122816859	0.0618364315769396	YBX3/HAMP/CGA/CITED2/PTEN/RGS2/IGF2/JARID2/DUSP6	9
GO:1903707	negative regulation of hemopoiesis	9/665	106/18722	0.0131760122816859	0.0618364315769396	FCGR2B/CD74/FGL2/MAFB/C1QC/ANXA1/LAG3/TRIB1/SMAD7	9
GO:0016051	carbohydrate biosynthetic process	14/665	202/18722	0.0133331825157092	0.0625150161349762	PGK1/FBP1/ATF3/TPI1/IRS2/PPP1CB/PPP1R3B/B3GNT7/GPI/PTGES3/CHST15/PTAFR/PTK2B/IGF2	14
GO:0046330	positive regulation of JNK cascade	8/665	89/18722	0.0137624395279722	0.0644044364104151	FCGR2B/NCF1/MYD88/PYCARD/RASSF2/SDCBP/PTK2B/RIPK2	8
GO:0001890	placenta development	11/665	144/18722	0.0138071681320941	0.0644044364104151	CEBPB/ADM/ST14/ANG/JUNB/GRB2/CITED2/SOCS3/PHLDA2/IGF2/SETD2	11
GO:0010324	membrane invagination	11/665	144/18722	0.0138071681320941	0.0644044364104151	FCGR2B/TREM2/CD300A/CD36/GSN/MSR1/FCHO2/RAC1/ITGAM/RHOA/RAB31	11
GO:0106106	cold-induced thermogenesis	11/665	144/18722	0.0138071681320941	0.0644044364104151	CXCR4/VEGFA/SCD/CEBPB/ACSL1/CD36/ARRDC3/GATM/G0S2/TLE3/RB1	11
GO:0120161	regulation of cold-induced thermogenesis	11/665	144/18722	0.0138071681320941	0.0644044364104151	CXCR4/VEGFA/SCD/CEBPB/ACSL1/CD36/ARRDC3/GATM/G0S2/TLE3/RB1	11
GO:0002534	cytokine production involved in inflammatory response	7/665	72/18722	0.013839826576725	0.0644044364104151	TREM2/ALOX5/CLEC7A/MYD88/PYCARD/PER1/PLD3	7
GO:0071479	cellular response to ionizing radiation	7/665	72/18722	0.013839826576725	0.0644044364104151	HAMP/NAMPT/GRB2/EGR1/RHOB/TANK/CDKN1A	7
GO:1900015	regulation of cytokine production involved in inflammatory response	7/665	72/18722	0.013839826576725	0.0644044364104151	TREM2/ALOX5/CLEC7A/MYD88/PYCARD/PER1/PLD3	7
GO:0032869	cellular response to insulin stimulus	14/665	203/18722	0.0138711324277703	0.0644897363573605	STAT1/PKM/ERRFI1/RAB8A/IRS2/PIP4K2A/GRB2/PTEN/SOCS3/INSIG2/RAB13/IGF2/RAB31/CPEB2	14
GO:0007229	integrin-mediated signaling pathway	9/665	107/18722	0.0139487681767814	0.0647295778138221	ISG15/LIMS1/TIMP1/ITGAM/FLNA/DST/PTK2B/FN1/NRP1	9
GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	9/665	107/18722	0.0139487681767814	0.0647295778138221	DAB2/SUMO2/PTEN/TRIB1/RBX1/LRRK2/PLK3/PTK2B/SMAD7	9
GO:0072521	purine-containing compound metabolic process	24/665	416/18722	0.0139790563457861	0.0648096175732806	NUPR1/LDHA/TREM2/DDIT4/HK2/PGK1/FBP1/ALDOA/PKM/ACSL1/HSD17B4/TPI1/PAPSS1/GAPDH/ENO1/RHOA/PAPSS2/GPI/LRRK2/ENO2/PGAM1/GUK1/ABHD14B/GALK1	24
GO:0046456	icosanoid biosynthetic process	6/665	56/18722	0.0141385232734997	0.0654268721315584	CD74/ALOX5/MIF/ALOX5AP/ANXA1/PTGES3	6
GO:0048008	platelet-derived growth factor receptor signaling pathway	6/665	56/18722	0.0141385232734997	0.0654268721315584	VEGFA/TXNIP/PTEN/PTPN12/TIPARP/NRP1	6
GO:2000058	regulation of ubiquitin-dependent protein catabolic process	12/665	164/18722	0.0142648651719643	0.0659501208415466	DAB2/SUMO2/N4BP1/PTEN/TRIB1/RBX1/LRRK2/SDCBP/PLK3/PTK2B/CAMLG/SMAD7	12
GO:0071383	cellular response to steroid hormone stimulus	14/665	204/18722	0.0144256849564188	0.0661521767950156	DDIT4/YWHAH/ZFP36L2/DAB2/ERRFI1/ZFP36/ANXA1/RHOA/PTGES3/EGFR/KLF9/EIF4E/PHB/PER1	14
GO:0002719	negative regulation of cytokine production involved in immune response	4/665	27/18722	0.0144549826960537	0.0661521767950156	HLA-F/BST2/HMOX1/SMAD7	4
GO:0002825	regulation of T-helper 1 type immune response	4/665	27/18722	0.0144549826960537	0.0661521767950156	SLC11A1/ANXA1/IL27RA/RIPK2	4
GO:0008053	mitochondrial fusion	4/665	27/18722	0.0144549826960537	0.0661521767950156	BNIP3/VAT1/TFRC/CHCHD3	4
GO:0018126	protein hydroxylation	4/665	27/18722	0.0144549826960537	0.0661521767950156	EGLN3/P4HA1/ERO1A/EGLN1	4
GO:0034143	regulation of toll-like receptor 4 signaling pathway	4/665	27/18722	0.0144549826960537	0.0661521767950156	TREM2/TNFAIP3/IFI35/WDFY1	4
GO:0039529	RIG-I signaling pathway	4/665	27/18722	0.0144549826960537	0.0661521767950156	OAS3/DDX60/OASL/PHB	4
GO:0060142	regulation of syncytium formation by plasma membrane fusion	4/665	27/18722	0.0144549826960537	0.0661521767950156	TREM2/CAPN2/CAMK1/TYROBP	4
GO:0060333	interferon-gamma-mediated signaling pathway	4/665	27/18722	0.0144549826960537	0.0661521767950156	STAT1/NMI/PARP9/IFNGR2	4
GO:0071624	positive regulation of granulocyte chemotaxis	4/665	27/18722	0.0144549826960537	0.0661521767950156	CD74/CXCL8/C5AR1/RAC1	4
GO:1903319	positive regulation of protein maturation	4/665	27/18722	0.0144549826960537	0.0661521767950156	ADAM8/GSN/ENO1/MMP14	4
GO:0032735	positive regulation of interleukin-12 production	5/665	41/18722	0.0145127888440116	0.0662337562486114	CLEC7A/CD36/IRF8/TLR2/RIPK2	5
GO:0050691	regulation of defense response to virus by host	5/665	41/18722	0.0145127888440116	0.0662337562486114	STAT1/PYCARD/TNFAIP3/DTX3L/PARP9	5
GO:0050856	regulation of T cell receptor signaling pathway	5/665	41/18722	0.0145127888440116	0.0662337562486114	CD300A/LGALS3/GBP1/CD81/PRNP	5
GO:0002679	respiratory burst involved in defense response	3/665	15/18722	0.0147518250423226	0.0666031288229788	TREM2/NCF1/GRN	3
GO:0010889	regulation of sequestering of triglyceride	3/665	15/18722	0.0147518250423226	0.0666031288229788	PLIN2/TREM2/ABHD5	3
GO:0032897	negative regulation of viral transcription	3/665	15/18722	0.0147518250423226	0.0666031288229788	IFITM3/ZFP36/LARP7	3
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	3/665	15/18722	0.0147518250423226	0.0666031288229788	CD74/MIF/CD44	3
GO:0045064	T-helper 2 cell differentiation	3/665	15/18722	0.0147518250423226	0.0666031288229788	ANXA1/CD86/NLRP3	3
GO:0045986	negative regulation of smooth muscle contraction	3/665	15/18722	0.0147518250423226	0.0666031288229788	DOCK4/RGS2/KCNMA1	3
GO:0048569	post-embryonic animal organ development	3/665	15/18722	0.0147518250423226	0.0666031288229788	LDHA/VEGFA/KLF4	3
GO:0051284	positive regulation of sequestering of calcium ion	3/665	15/18722	0.0147518250423226	0.0666031288229788	CALM1/CLIC2/CALM3	3
GO:0098760	response to interleukin-7	3/665	15/18722	0.0147518250423226	0.0666031288229788	LSP1/YBX1/IL7R	3
GO:0098761	cellular response to interleukin-7	3/665	15/18722	0.0147518250423226	0.0666031288229788	LSP1/YBX1/IL7R	3
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	3/665	15/18722	0.0147518250423226	0.0666031288229788	ZFP36L2/ZFP36/TOB1	3
GO:0007173	epidermal growth factor receptor signaling pathway	9/665	108/18722	0.0147545361839235	0.0666031288229788	IFI6/ERRFI1/NCF1/GRB2/RASSF2/PTPN12/EGFR/PLAUR/PTK2B	9
GO:0010001	glial cell differentiation	15/665	225/18722	0.014782783527406	0.066670085418519	VIM/CXCR4/TREM2/CD9/NDRG1/C5AR1/BNIP3/PTEN/RHOA/EGFR/PLEC/GRN/S100A8/TLR2/C1QA	15
GO:0043299	leukocyte degranulation	7/665	73/18722	0.0148538901343741	0.0668694148259415	FCGR2B/CD300A/HLA-F/HMOX1/ITGAM/PTAFR/SPI1	7
GO:0051865	protein autoubiquitination	7/665	73/18722	0.0148538901343741	0.0668694148259415	UBE2B/DTX3L/RBX1/LRRK2/RNF141/UBE2D2/RNF187	7
GO:0019216	regulation of lipid metabolic process	20/665	331/18722	0.0150267686353164	0.0675864616448166	TREM2/APOE/CAPN2/APOC1/CD74/ADM/TSPO/IRS2/PIP4K2A/IDH1/CGA/DNAJC15/ANXA1/EGR1/INSIG2/EDF1/PTK2B/ABHD5/CD81/PSAP	20
GO:0032409	regulation of transporter activity	19/665	310/18722	0.0152708428332032	0.0686221418454068	TREM2/YWHAH/SGK1/CALM1/FXYD5/GLRX/CLIC2/PTEN/KCNE1/IFNGR2/PTAFR/AHNAK/WNK1/CALM3/KIF5B/C4orf3/PTK2B/EPHB2/PRNP	19
GO:0006949	syncytium formation	6/665	57/18722	0.015341791740439	0.0688165207129798	TREM2/CD9/CAPN2/CAMK1/TYROBP/CD81	6
GO:0010883	regulation of lipid storage	6/665	57/18722	0.015341791740439	0.0688165207129798	PLIN2/TREM2/NFKBIA/CD36/MSR1/ABHD5	6
GO:0019935	cyclic-nucleotide-mediated signaling	8/665	91/18722	0.0155807842977579	0.0696340169447791	APOE/ADM/AHR/CD36/UBE2B/RGS2/PTK2B/CAP1	8
GO:0017038	protein import	14/665	206/18722	0.015585876445805	0.0696340169447791	APOE/TXNIP/NFKBIA/CD36/NUP58/DNAJC15/FLNA/HCLS1/LMNA/LRRK2/KPNA3/CDKN1A/MDFIC/ELAVL1	14
GO:0032414	positive regulation of ion transmembrane transporter activity	9/665	109/18722	0.0155940967524224	0.0696340169447791	TREM2/CALM1/GLRX/IFNGR2/PTAFR/WNK1/CALM3/KIF5B/EPHB2	9
GO:0034766	negative regulation of ion transmembrane transport	9/665	109/18722	0.0155940967524224	0.0696340169447791	CALM1/HAMP/CLIC2/PTEN/KCNE1/RGS2/CALM3/C4orf3/EPHB2	9
GO:0043266	regulation of potassium ion transport	9/665	109/18722	0.0155940967524224	0.0696340169447791	TREM2/PTEN/FLNA/KCNE1/WNK1/KIF5B/KCNAB2/PTK2B/PRNP	9
GO:0031345	negative regulation of cell projection organization	13/665	186/18722	0.0156816842599479	0.0699622717880979	VIM/LGALS1/B2M/APOE/YWHAH/PTEN/FLNA/RHOA/LRRK2/ABI3/EPHB2/PRNP/NRP1	13
GO:0002437	inflammatory response to antigenic stimulus	7/665	74/18722	0.0159197816070821	0.0708972352931881	FCGR2B/HLA-DRB1/TREM2/HLA-E/CD81/CD68/GPX1	7
GO:1903201	regulation of oxidative stress-induced cell death	7/665	74/18722	0.0159197816070821	0.0708972352931881	TREM2/PAGE4/SOD2/MCL1/LRRK2/TXN/GPX1	7
GO:0033574	response to testosterone	5/665	42/18722	0.0160059096535934	0.0710262240878207	DUSP1/CSNK2B/TSPO/MSN/GPI	5
GO:0072595	maintenance of protein localization in organelle	5/665	42/18722	0.0160059096535934	0.0710262240878207	HK2/TSPO/INSIG2/TXN/ARL2BP	5
GO:0090317	negative regulation of intracellular protein transport	5/665	42/18722	0.0160059096535934	0.0710262240878207	CD36/KCNE1/LRRK2/TXN/MDFIC	5
GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	5/665	42/18722	0.0160059096535934	0.0710262240878207	JUN/KLF4/FOS/EGR1/SPI1	5
GO:0010818	T cell chemotaxis	4/665	28/18722	0.016401464934662	0.0725164535203357	GPR183/CXCL16/PLEC/WNK1	4
GO:0034123	positive regulation of toll-like receptor signaling pathway	4/665	28/18722	0.016401464934662	0.0725164535203357	RSAD2/IFI35/TLR2/WDFY1	4
GO:0045589	regulation of regulatory T cell differentiation	4/665	28/18722	0.016401464934662	0.0725164535203357	HLA-DRB1/IL4I1/HLA-DRA/LAG3	4
GO:0090200	positive regulation of release of cytochrome c from mitochondria	4/665	28/18722	0.016401464934662	0.0725164535203357	BNIP3/PYCARD/FAM162A/PLAUR	4
GO:0062012	regulation of small molecule metabolic process	20/665	334/18722	0.0164146901831746	0.0725164535203357	NUPR1/TREM2/APOE/DDIT4/APOC1/CD74/FBP1/ADM/IRS2/PPP1CB/ENO1/PPP1R3B/ANXA1/EGR1/PTAFR/PHLDA2/PGAM1/INSIG2/PTK2B/IGF2	20
GO:0048259	regulation of receptor-mediated endocytosis	9/665	110/18722	0.0164682238077757	0.0726238441212467	VEGFA/B2M/APOC1/DAB2/RIN3/RAC1/SDCBP/ANXA2/PIK3CB	9
GO:0090174	organelle membrane fusion	9/665	110/18722	0.0164682238077757	0.0726238441212467	SAMD9/RAB8A/PIP4K2A/RAB20/ANXA1/KIF5B/STX3/RAB13/ANXA2	9
GO:1903312	negative regulation of mRNA metabolic process	8/665	92/18722	0.0165523978599873	0.0729303345426747	SLC11A1/YBX3/ZFP36/MYD88/YBX1/HNRNPA0/TOB1/ELAVL1	8
GO:0045926	negative regulation of growth	16/665	249/18722	0.0166061918883507	0.0730084241295655	BTG1/FBP1/BST2/MT1X/ENO1/CGA/CITED2/PTEN/RGS2/CDKN1A/ACVRL1/RB1/CCDC85B/PHB/JARID2/NRP1	16
GO:0002931	response to ischemia	6/665	58/18722	0.0166141906822009	0.0730084241295655	TREM2/HK2/EIF4EBP1/EGR1/SQSTM1/PIK3CB	6
GO:0043666	regulation of phosphoprotein phosphatase activity	6/665	58/18722	0.0166141906822009	0.0730084241295655	CD300A/CALM1/CSNK2B/PPP1R15A/LGALS3/CALM3	6
GO:0034765	regulation of ion transmembrane transport	27/665	491/18722	0.0169357667288755	0.074355795620593	TREM2/YWHAH/CALM1/FXYD5/KCNQ3/GLRX/HAMP/CLIC2/CLIC1/PTEN/FLNA/KCNE1/RGS2/IFNGR2/PTAFR/AHNAK/WNK1/CALM3/KIF5B/C4orf3/KCNAB2/PTK2B/DIAPH1/KCNMA1/EPHB2/SCN9A/PRNP	27
GO:0033077	T cell differentiation in thymus	7/665	75/18722	0.0170387934881521	0.0747421038271105	B2M/CD74/ADAM8/ZFP36L2/MAFB/IL7R/SOS2	7
GO:0045834	positive regulation of lipid metabolic process	11/665	149/18722	0.0174160261477616	0.0760527105640706	APOE/CAPN2/APOC1/CD74/ADM/IRS2/CGA/ANXA1/PTK2B/ABHD5/CD81	11
GO:1902807	negative regulation of cell cycle G1/S phase transition	8/665	93/18722	0.0175669402305872	0.0760527105640706	GPNMB/KLF4/RPS27L/PTEN/RPA2/PLK3/CDKN1A/RB1	8
GO:0120178	steroid hormone biosynthetic process	5/665	43/18722	0.017597893133707	0.0760527105640706	ADM/TSPO/HSD17B11/EGR1/HSD17B1	5
GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	5/665	43/18722	0.017597893133707	0.0760527105640706	SOD2/PTEN/HMOX1/RHOA/CDKN1A	5
GO:0002827	positive regulation of T-helper 1 type immune response	3/665	16/18722	0.0176851315598278	0.0760527105640706	SLC11A1/IL27RA/RIPK2	3
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	3/665	16/18722	0.0176851315598278	0.0760527105640706	RPS27L/CDKN1A/ZNF385A	3
GO:0017014	protein nitrosylation	3/665	16/18722	0.0176851315598278	0.0760527105640706	GAPDH/S100A8/TXN	3
GO:0018119	peptidyl-cysteine S-nitrosylation	3/665	16/18722	0.0176851315598278	0.0760527105640706	GAPDH/S100A8/TXN	3
GO:0034138	toll-like receptor 3 signaling pathway	3/665	16/18722	0.0176851315598278	0.0760527105640706	OAS1/TNFAIP3/WDFY1	3
GO:0035970	peptidyl-threonine dephosphorylation	3/665	16/18722	0.0176851315598278	0.0760527105640706	DUSP1/PPP2CB/DUSP18	3
GO:0044804	autophagy of nucleus	3/665	16/18722	0.0176851315598278	0.0760527105640706	WDR45B/ATG3/WIPI2	3
GO:0045651	positive regulation of macrophage differentiation	3/665	16/18722	0.0176851315598278	0.0760527105640706	HCLS1/TRIB1/RB1	3
GO:0051238	sequestering of metal ion	3/665	16/18722	0.0176851315598278	0.0760527105640706	FTH1/FTL/S100A8	3
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	3/665	16/18722	0.0176851315598278	0.0760527105640706	NFKBIA/TNFAIP3/RIPK2	3
GO:0071361	cellular response to ethanol	3/665	16/18722	0.0176851315598278	0.0760527105640706	SOD2/PTEN/SPI1	3
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	3/665	16/18722	0.0176851315598278	0.0760527105640706	OAS1/OAS3/CLEC7A	3
GO:0097284	hepatocyte apoptotic process	3/665	16/18722	0.0176851315598278	0.0760527105640706	GSN/KRT18/RB1	3
GO:1901163	regulation of trophoblast cell migration	3/665	16/18722	0.0176851315598278	0.0760527105640706	VEGFA/TIMP1/SMURF2	3
GO:1905906	regulation of amyloid fibril formation	3/665	16/18722	0.0176851315598278	0.0760527105640706	TREM2/APOE/PFDN6	3
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	3/665	16/18722	0.0176851315598278	0.0760527105640706	GLRX/WNK1/KIF5B	3
GO:2001044	regulation of integrin-mediated signaling pathway	3/665	16/18722	0.0176851315598278	0.0760527105640706	LIMS1/TIMP1/FLNA	3
GO:2001212	regulation of vasculogenesis	3/665	16/18722	0.0176851315598278	0.0760527105640706	ADM/RAP1A/RIN2	3
GO:0031214	biomineral tissue development	12/665	169/18722	0.0176895238253653	0.0760527105640706	ISG15/SRGN/GPNMB/ALOX5/CEBPB/SNX10/ECM1/KLF10/FBN2/FBXL15/PTK2B/FAM20C	12
GO:0018105	peptidyl-serine phosphorylation	19/665	315/18722	0.0177619085118957	0.0762979129681259	VEGFA/DDIT4/SGK1/MIF/CD44/TERF2IP/RASSF2/PTEN/PRKX/HCLS1/EGFR/LRRK2/WNK1/TXN/CAMK1/TFRC/HAX1/SMAD7/RIPK2	19
GO:0043407	negative regulation of MAP kinase activity	6/665	59/18722	0.0179574622522223	0.0770713189926984	APOE/CD300A/DUSP1/RGS2/AIDA/PIK3CB	6
GO:0051604	protein maturation	18/665	294/18722	0.018062025078825	0.0774532050403455	SRGN/CAPN2/CTSH/ADAM8/PGK1/ERO1A/CARD16/GSN/PYCARD/ENO1/LRRK2/MMP14/PLAU/APH1A/TMEM59/CPD/RIPK2/PRNP	18
GO:0090257	regulation of muscle system process	16/665	252/18722	0.0183767609398864	0.0786043324257886	CALM1/KLF4/ERRFI1/HAMP/CLIC2/ENO1/DOCK4/RHOA/RGS2/LMNA/PTAFR/CALM3/KCNMA1/NR4A1/JARID2/SMAD7	16
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	4/665	29/18722	0.0185044404302158	0.0786043324257886	FCGR2B/HLA-DRB1/TREM2/GPX1	4
GO:0005979	regulation of glycogen biosynthetic process	4/665	29/18722	0.0185044404302158	0.0786043324257886	IRS2/PPP1CB/PPP1R3B/IGF2	4
GO:0010955	negative regulation of protein processing	4/665	29/18722	0.0185044404302158	0.0786043324257886	CARD16/LRRK2/TMEM59/PRNP	4
GO:0010962	regulation of glucan biosynthetic process	4/665	29/18722	0.0185044404302158	0.0786043324257886	IRS2/PPP1CB/PPP1R3B/IGF2	4
GO:0021602	cranial nerve morphogenesis	4/665	29/18722	0.0185044404302158	0.0786043324257886	MAFB/CITED2/EPHB2/NRP1	4
GO:0033028	myeloid cell apoptotic process	4/665	29/18722	0.0185044404302158	0.0786043324257886	IRF7/PTEN/ANXA1/PIK3CB	4
GO:0048679	regulation of axon regeneration	4/665	29/18722	0.0185044404302158	0.0786043324257886	KLF4/PTEN/FLNA/GRN	4
GO:0071549	cellular response to dexamethasone stimulus	4/665	29/18722	0.0185044404302158	0.0786043324257886	DDIT4/ERRFI1/EGFR/EIF4E	4
GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	4/665	29/18722	0.0185044404302158	0.0786043324257886	TREM2/SOD2/MCL1/GPX1	4
GO:1903318	negative regulation of protein maturation	4/665	29/18722	0.0185044404302158	0.0786043324257886	CARD16/LRRK2/TMEM59/PRNP	4
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	8/665	94/18722	0.0186253687997292	0.078781347178429	HERC5/TNFAIP3/PTEN/CCNY/EGFR/CDKN1A/CCNI/CDKN1C	8
GO:0002042	cell migration involved in sprouting angiogenesis	8/665	94/18722	0.0186253687997292	0.078781347178429	VEGFA/KLF4/HMOX1/ANXA1/RHOA/MAP3K3/NR4A1/NRP1	8
GO:0019080	viral gene expression	8/665	94/18722	0.0186253687997292	0.078781347178429	JUN/IFITM3/SSB/ZFP36/PARP9/LARP7/MDFIC/RSF1	8
GO:0032091	negative regulation of protein binding	8/665	94/18722	0.0186253687997292	0.078781347178429	IFIT1/IFIT2/B2M/DAB2/CARD16/LRRK2/CDKN1A/CAMK1	8
GO:1903035	negative regulation of response to wounding	8/665	94/18722	0.0186253687997292	0.078781347178429	CD9/APOE/ALOX5/SERPING1/PTEN/PLAU/ANXA2/SIGLEC10	8
GO:0051258	protein polymerization	18/665	296/18722	0.0192004364816172	0.0809088186206858	CAPG/MYADM/GSN/ANG/GMFG/ARPC4/MAPRE1/PYCARD/GRB2/RAC1/RHOA/HCLS1/COTL1/TMSB10/PTK2B/DIAPH1/HAX1/IQGAP2	18
GO:0110148	biomineralization	12/665	171/18722	0.0192197338211617	0.0809088186206858	ISG15/SRGN/GPNMB/ALOX5/CEBPB/SNX10/ECM1/KLF10/FBN2/FBXL15/PTK2B/FAM20C	12
GO:0005978	glycogen biosynthetic process	5/665	44/18722	0.0192911368341072	0.0809088186206858	IRS2/PPP1CB/PPP1R3B/PTGES3/IGF2	5
GO:0009250	glucan biosynthetic process	5/665	44/18722	0.0192911368341072	0.0809088186206858	IRS2/PPP1CB/PPP1R3B/PTGES3/IGF2	5
GO:0021762	substantia nigra development	5/665	44/18722	0.0192911368341072	0.0809088186206858	YWHAH/CALM1/DYNLL1/RHOA/CALM3	5
GO:0031295	T cell costimulation	5/665	44/18722	0.0192911368341072	0.0809088186206858	LGALS1/TNFSF13B/TNFRSF14/CD86/CD81	5
GO:0032881	regulation of polysaccharide metabolic process	5/665	44/18722	0.0192911368341072	0.0809088186206858	IRS2/PPP1CB/PPP1R3B/PHLDA2/IGF2	5
GO:0044058	regulation of digestive system process	5/665	44/18722	0.0192911368341072	0.0809088186206858	SGK1/TYMP/HAMP/EPB41/WNK1	5
GO:0045124	regulation of bone resorption	5/665	44/18722	0.0192911368341072	0.0809088186206858	ADAM8/HAMP/TNFAIP3/EGFR/TFRC	5
GO:0060711	labyrinthine layer development	5/665	44/18722	0.0192911368341072	0.0809088186206858	ADM/ST14/JUNB/GRB2/SOCS3	5
GO:0006081	cellular aldehyde metabolic process	6/665	60/18722	0.0193732874038426	0.0810481804689373	TPI1/IDH1/ESD/CYP1B1/ALDH3A2/HAGH	6
GO:0031102	neuron projection regeneration	6/665	60/18722	0.0193732874038426	0.0810481804689373	KLF4/ADM/TSPO/PTEN/FLNA/GRN	6
GO:0061951	establishment of protein localization to plasma membrane	6/665	60/18722	0.0193732874038426	0.0810481804689373	RAB8A/VAMP5/GOLGA7/KRT18/RAB31/ATP2C1	6
GO:0015980	energy derivation by oxidation of organic compounds	19/665	318/18722	0.0194015630153894	0.081098207053394	NUPR1/SDHD/IRS2/SCO2/IDH1/BNIP3/PPP1CB/BLOC1S1/PPP1R3B/DNAJC15/RHOA/PTGES3/PLEC/COA6/PHLDA2/SDHB/CYCS/IGF2/COX5B	19
GO:0021675	nerve development	7/665	77/18722	0.0194412067311617	0.0811956281124989	SULF2/SLC1A3/MAFB/CITED2/GABRB2/EPHB2/NRP1	7
GO:0043270	positive regulation of ion transport	17/665	275/18722	0.0194729706427203	0.0812600034377161	TREM2/CALM1/CEBPB/LILRA5/TSPO/GLRX/LGALS3/FLNA/KCNE1/IFNGR2/PTAFR/WNK1/CALM3/KIF5B/EPHB2/KMO/CXCL12	17
GO:0009749	response to glucose	14/665	212/18722	0.019498140349168	0.081296776455843	HLA-DRB1/LDHA/TREM2/LGALS1/TXNIP/GLUL/DYNLL1/IRS2/PTEN/RAC1/RHOA/EGR1/KIF5B/PTK2B	14
GO:0036473	cell death in response to oxidative stress	8/665	95/18722	0.019728624473865	0.0821888211526482	TREM2/PAGE4/SOD2/MCL1/LRRK2/TXN/CYP1B1/GPX1	8
GO:0098754	detoxification	11/665	152/18722	0.019894259345758	0.082809437980249	APOE/SOD2/HBG1/CD36/GLRX/CLIC2/MT1X/ALOX5AP/TXN/ESD/GPX1	11
GO:0042770	signal transduction in response to DNA damage	12/665	172/18722	0.0200209078914392	0.0832668721510065	CD74/NDRG1/RPS27L/MIF/CD44/GRB2/RPA2/PLK3/CDKN1A/FOXN3/ZNF385A/XPC	12
GO:0051924	regulation of calcium ion transport	16/665	255/18722	0.0202886431636111	0.0843098298688523	CXCR4/CALM1/LILRA5/TSPO/CLIC2/LGALS3/RHOA/EPB41/SARAF/AHNAK/CALM3/C4orf3/PTK2B/DIAPH1/CXCL12/PRNP	16
GO:0046660	female sex differentiation	9/665	114/18722	0.0203255975096277	0.0843928317651208	NUPR1/LHFPL2/VEGFA/CEBPB/MERTK/ANG/IDH1/MMP14/TIPARP	9
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	7/665	78/18722	0.0207270451450133	0.084801509324439	CTSH/EGLN3/RPS27L/PYCARD/FAM162A/CYCS/S100A8	7
GO:0034637	cellular carbohydrate biosynthetic process	7/665	78/18722	0.0207270451450133	0.084801509324439	FBP1/IRS2/PPP1CB/PPP1R3B/B3GNT7/PTGES3/IGF2	7
GO:0061045	negative regulation of wound healing	7/665	78/18722	0.0207270451450133	0.084801509324439	CD9/APOE/ALOX5/SERPING1/PTEN/PLAU/ANXA2	7
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	7/665	78/18722	0.0207270451450133	0.084801509324439	VEGFA/KLF4/HMOX1/ANXA1/RHOA/MAP3K3/NRP1	7
GO:0008209	androgen metabolic process	4/665	30/18722	0.0207671236434691	0.084801509324439	ADM/HSD17B4/HSD17B11/TIPARP	4
GO:0019674	NAD metabolic process	4/665	30/18722	0.0207671236434691	0.084801509324439	LDHA/HK2/ENO1/KMO	4
GO:0031571	mitotic G1 DNA damage checkpoint signaling	4/665	30/18722	0.0207671236434691	0.084801509324439	RPS27L/RPA2/PLK3/CDKN1A	4
GO:0033137	negative regulation of peptidyl-serine phosphorylation	4/665	30/18722	0.0207671236434691	0.084801509324439	DDIT4/RASSF2/PTEN/SMAD7	4
GO:0036296	response to increased oxygen levels	4/665	30/18722	0.0207671236434691	0.084801509324439	BNIP3/ATP6V1G1/PDPN/CDKN1A	4
GO:0043032	positive regulation of macrophage activation	4/665	30/18722	0.0207671236434691	0.084801509324439	TREM2/JUND/HAMP/LRRK2	4
GO:0045940	positive regulation of steroid metabolic process	4/665	30/18722	0.0207671236434691	0.084801509324439	APOE/APOC1/ADM/CGA	4
GO:0048147	negative regulation of fibroblast proliferation	4/665	30/18722	0.0207671236434691	0.084801509324439	NUPR1/CD300A/FTH1/IFI30	4
GO:0051968	positive regulation of synaptic transmission, glutamatergic	4/665	30/18722	0.0207671236434691	0.084801509324439	GLUL/EGFR/PTK2B/KMO	4
GO:0090151	establishment of protein localization to mitochondrial membrane	4/665	30/18722	0.0207671236434691	0.084801509324439	CALM1/CALM3/TIMM8B/TIMM10	4
GO:0099068	postsynapse assembly	4/665	30/18722	0.0207671236434691	0.084801509324439	IL1RAP/PTEN/ABI3/EPHB2	4
GO:0010469	regulation of signaling receptor activity	12/665	173/18722	0.0208466905911262	0.084801509324439	FCGR2B/ERRFI1/NCF1/LY6E/CGA/PTEN/IFNGR2/PHLDA2/PLAU/PTK2B/EPHB2/NRP1	12
GO:0010769	regulation of cell morphogenesis involved in differentiation	8/665	96/18722	0.0208776303915341	0.084801509324439	LIMS1/S100A10/MYADM/RAC1/GBP1/PDPN/FLNA/NRP1	8
GO:0001780	neutrophil homeostasis	3/665	17/18722	0.0209188431452238	0.084801509324439	MERTK/ANXA1/PIK3CB	3
GO:0010224	response to UV-B	3/665	17/18722	0.0209188431452238	0.084801509324439	CRIP1/CDKN1A/XPC	3
GO:0035855	megakaryocyte development	3/665	17/18722	0.0209188431452238	0.084801509324439	PIP4K2A/ABI1/ZNF385A	3
GO:0042772	DNA damage response, signal transduction resulting in transcription	3/665	17/18722	0.0209188431452238	0.084801509324439	RPS27L/CDKN1A/ZNF385A	3
GO:0044539	long-chain fatty acid import into cell	3/665	17/18722	0.0209188431452238	0.084801509324439	ACSL1/CD36/IRS2	3
GO:0045591	positive regulation of regulatory T cell differentiation	3/665	17/18722	0.0209188431452238	0.084801509324439	HLA-DRB1/IL4I1/HLA-DRA	3
GO:0060977	coronary vasculature morphogenesis	3/665	17/18722	0.0209188431452238	0.084801509324439	VEGFA/SETD2/NRP1	3
GO:0061298	retina vasculature development in camera-type eye	3/665	17/18722	0.0209188431452238	0.084801509324439	ACVRL1/CYP1B1/NRP1	3
GO:0061450	trophoblast cell migration	3/665	17/18722	0.0209188431452238	0.084801509324439	VEGFA/TIMP1/SMURF2	3
GO:0070206	protein trimerization	3/665	17/18722	0.0209188431452238	0.084801509324439	CD74/MIF/ALOX5AP	3
GO:0072673	lamellipodium morphogenesis	3/665	17/18722	0.0209188431452238	0.084801509324439	CD44/ABI1/PDPN	3
GO:0140354	lipid import into cell	3/665	17/18722	0.0209188431452238	0.084801509324439	ACSL1/CD36/IRS2	3
GO:0045930	negative regulation of mitotic cell cycle	15/665	235/18722	0.0210464810647091	0.0852087904053376	GPNMB/DUSP1/ZFP36L2/BTG1/KLF4/RPS27L/PTEN/EGFR/RPA2/PLK3/CDKN1A/FOXN3/RB1/CDKN1C/XPC	15
GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	5/665	45/18722	0.0210878897783834	0.0852087904053376	TREM2/SOD2/MCL1/CYP1B1/GPX1	5
GO:0042551	neuron maturation	5/665	45/18722	0.0210878897783834	0.0852087904053376	NR4A2/LRRK2/RB1/AGRN/C1QA	5
GO:1904646	cellular response to amyloid-beta	5/665	45/18722	0.0210878897783834	0.0852087904053376	FCGR2B/TREM2/CD36/NAMPT/PRNP	5
GO:0032147	activation of protein kinase activity	10/665	134/18722	0.0212782251007862	0.0858382944406717	SLC11A1/VEGFA/CD300A/ANG/WNK1/TXN/CD86/PTK2B/PHB/PRNP	10
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	10/665	134/18722	0.0212782251007862	0.0858382944406717	DAB2/SUMO2/N4BP1/TRIB1/RBX1/LRRK2/SDCBP/PLK3/CAMLG/SMAD7	10
GO:0006401	RNA catabolic process	17/665	278/18722	0.0213816739980126	0.0861856608030191	VIM/SLC11A1/OAS2/RNASE6/ZFP36L2/YBX3/RNASET2/SSB/ZFP36/ANG/MYD88/YBX1/HNRNPA0/TOB1/HELZ2/ELAVL1/LSM6	17
GO:0120162	positive regulation of cold-induced thermogenesis	8/665	97/18722	0.0220732906707626	0.0889013408700892	CXCR4/VEGFA/SCD/CEBPB/ACSL1/CD36/GATM/G0S2	8
GO:0042157	lipoprotein metabolic process	10/665	135/18722	0.0222788793493632	0.0896567047500689	APOE/APOC1/GLUL/APOL4/ZDHHC20/GOLGA7/WDR45B/CTSD/WIPI2/APOL6	10
GO:0007006	mitochondrial membrane organization	9/665	116/18722	0.0224811779466697	0.0903976168243918	HK2/CALM1/BNIP3L/BNIP3/BLOC1S2/CALM3/TIMM8B/TIMM10/CHCHD3	9
GO:0031294	lymphocyte costimulation	5/665	46/18722	0.0229902483606308	0.0922207702601576	LGALS1/TNFSF13B/TNFRSF14/CD86/CD81	5
GO:0034198	cellular response to amino acid starvation	5/665	46/18722	0.0229902483606308	0.0922207702601576	EIF2AK2/ATF3/SLC38A2/RRAGD/CDKN1A	5
GO:1900271	regulation of long-term synaptic potentiation	5/665	46/18722	0.0229902483606308	0.0922207702601576	APOE/SQSTM1/TYROBP/EPHB2/PRNP	5
GO:0001516	prostaglandin biosynthetic process	4/665	31/18722	0.023192310949873	0.0923604049846705	CD74/MIF/ANXA1/PTGES3	4
GO:0002230	positive regulation of defense response to virus by host	4/665	31/18722	0.023192310949873	0.0923604049846705	STAT1/PYCARD/DTX3L/PARP9	4
GO:0002717	positive regulation of natural killer cell mediated immunity	4/665	31/18722	0.023192310949873	0.0923604049846705	HLA-F/CADM1/LAG3/HLA-E	4
GO:0044819	mitotic G1/S transition checkpoint signaling	4/665	31/18722	0.023192310949873	0.0923604049846705	RPS27L/RPA2/PLK3/CDKN1A	4
GO:0045066	regulatory T cell differentiation	4/665	31/18722	0.023192310949873	0.0923604049846705	HLA-DRB1/IL4I1/HLA-DRA/LAG3	4
GO:0046457	prostanoid biosynthetic process	4/665	31/18722	0.023192310949873	0.0923604049846705	CD74/MIF/ANXA1/PTGES3	4
GO:0055022	negative regulation of cardiac muscle tissue growth	4/665	31/18722	0.023192310949873	0.0923604049846705	CITED2/PTEN/RGS2/JARID2	4
GO:0061117	negative regulation of heart growth	4/665	31/18722	0.023192310949873	0.0923604049846705	CITED2/PTEN/RGS2/JARID2	4
GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	4/665	31/18722	0.023192310949873	0.0923604049846705	PEA15/TNFAIP3/HMOX1/GPX1	4
GO:0099024	plasma membrane invagination	10/665	136/18722	0.0233132273951641	0.0927063610198068	FCGR2B/TREM2/CD300A/CD36/GSN/MSR1/RAC1/ITGAM/RHOA/RAB31	10
GO:1904029	regulation of cyclin-dependent protein kinase activity	8/665	98/18722	0.0233164891900923	0.0927063610198068	HERC5/TNFAIP3/PTEN/CCNY/EGFR/CDKN1A/CCNI/CDKN1C	8
GO:0071229	cellular response to acid chemical	7/665	80/18722	0.0234738262963645	0.0932573274923515	VEGFA/CAPN2/CEBPB/KLF2/LAMTOR5/PLEC/RRAGD	7
GO:0032233	positive regulation of actin filament bundle assembly	6/665	63/18722	0.0240719092128033	0.0950989298294154	S100A10/RAC1/FLNA/RHOA/RHOC/NRP1	6
GO:0050854	regulation of antigen receptor-mediated signaling pathway	6/665	63/18722	0.0240719092128033	0.0950989298294154	FCGR2B/CD300A/LGALS3/GBP1/CD81/PRNP	6
GO:0007163	establishment or maintenance of cell polarity	14/665	218/18722	0.0241111803192786	0.0950989298294154	GSN/MSN/RAC1/PARVB/RHOA/LMNA/RHOB/RHOC/DST/LIN7C/RND3/PTK2B/DOCK8/CAP1	14
GO:1903532	positive regulation of secretion by cell	17/665	282/18722	0.0241445872386973	0.0950989298294154	HLA-DRB1/TREM2/ADAM8/GLUL/DYNLL1/HLA-F/IRS2/ANG/RAC1/ITGAM/EGFR/PTAFR/SDCBP/KIF5B/KMO/TLR2/CXCL12	17
GO:0010977	negative regulation of neuron projection development	10/665	137/18722	0.0243818404203175	0.0950989298294154	VIM/LGALS1/B2M/APOE/PTEN/FLNA/RHOA/LRRK2/EPHB2/NRP1	10
GO:0045471	response to ethanol	10/665	137/18722	0.0243818404203175	0.0950989298294154	SOD2/HAMP/PTEN/EIF4EBP1/RHOA/RGS2/S100A8/SPI1/PTK2B/NLRP3	10
GO:0043405	regulation of MAP kinase activity	12/665	177/18722	0.0244042189323118	0.0950989298294154	VEGFA/APOE/CD300A/DUSP1/ADAM8/RGS2/TRIB1/EGFR/AIDA/LRRK2/PTK2B/PIK3CB	12
GO:0071466	cellular response to xenobiotic stimulus	12/665	177/18722	0.0244042189323118	0.0950989298294154	CXCR4/FBP1/ACSL1/AHR/RAP1A/EGFR/VKORC1/GUK1/TFRC/RB1/CYP1B1/PRNP	12
GO:0010663	positive regulation of striated muscle cell apoptotic process	3/665	18/18722	0.024454010527564	0.0950989298294154	CAPN2/BNIP3/PTEN	3
GO:0010666	positive regulation of cardiac muscle cell apoptotic process	3/665	18/18722	0.024454010527564	0.0950989298294154	CAPN2/BNIP3/PTEN	3
GO:0030730	sequestering of triglyceride	3/665	18/18722	0.024454010527564	0.0950989298294154	PLIN2/TREM2/ABHD5	3
GO:0030889	negative regulation of B cell proliferation	3/665	18/18722	0.024454010527564	0.0950989298294154	FCGR2B/CD300A/TYROBP	3
GO:0034433	steroid esterification	3/665	18/18722	0.024454010527564	0.0950989298294154	APOE/APOC1/SOAT1	3
GO:0034434	sterol esterification	3/665	18/18722	0.024454010527564	0.0950989298294154	APOE/APOC1/SOAT1	3
GO:0034435	cholesterol esterification	3/665	18/18722	0.024454010527564	0.0950989298294154	APOE/APOC1/SOAT1	3
GO:0035743	CD4-positive, alpha-beta T cell cytokine production	3/665	18/18722	0.024454010527564	0.0950989298294154	RSAD2/NLRP3/CD81	3
GO:0045116	protein neddylation	3/665	18/18722	0.024454010527564	0.0950989298294154	RBX1/UBE2F/NEDD8	3
GO:0051895	negative regulation of focal adhesion assembly	3/665	18/18722	0.024454010527564	0.0950989298294154	PTEN/MMP14/ACVRL1	3
GO:0060008	Sertoli cell differentiation	3/665	18/18722	0.024454010527564	0.0950989298294154	HSD17B4/FLNA/RAB13	3
GO:0071800	podosome assembly	3/665	18/18722	0.024454010527564	0.0950989298294154	GSN/MSN/RHOA	3
GO:0097094	craniofacial suture morphogenesis	3/665	18/18722	0.024454010527564	0.0950989298294154	INSIG2/MMP14/FOXN3	3
GO:0097107	postsynaptic density assembly	3/665	18/18722	0.024454010527564	0.0950989298294154	IL1RAP/PTEN/ABI3	3
GO:0150078	positive regulation of neuroinflammatory response	3/665	18/18722	0.024454010527564	0.0950989298294154	NUPR1/TREM2/LRRK2	3
GO:0150118	negative regulation of cell-substrate junction organization	3/665	18/18722	0.024454010527564	0.0950989298294154	PTEN/MMP14/ACVRL1	3
GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	3/665	18/18722	0.024454010527564	0.0950989298294154	ZFP36L2/ZFP36/TOB1	3
GO:1900242	regulation of synaptic vesicle endocytosis	3/665	18/18722	0.024454010527564	0.0950989298294154	CALM1/LRRK2/CALM3	3
GO:1902001	fatty acid transmembrane transport	3/665	18/18722	0.024454010527564	0.0950989298294154	ACSL1/CD36/IRS2	3
GO:1990845	adaptive thermogenesis	11/665	157/18722	0.0245896086705993	0.0954740041948295	CXCR4/VEGFA/SCD/CEBPB/ACSL1/CD36/ARRDC3/GATM/G0S2/TLE3/RB1	11
GO:0030838	positive regulation of actin filament polymerization	8/665	99/18722	0.0246080884051462	0.0954740041948295	GSN/GMFG/ARPC4/PYCARD/GRB2/RHOA/PTK2B/IQGAP2	8
GO:0060291	long-term synaptic potentiation	8/665	99/18722	0.0246080884051462	0.0954740041948295	APOE/PTEN/STX3/PTK2B/SQSTM1/TYROBP/EPHB2/PRNP	8
GO:0007179	transforming growth factor beta receptor signaling pathway	13/665	198/18722	0.0248285032440487	0.0962540258369126	JUN/DAB2/SKIL/SMURF2/CITED2/PEG10/FOS/FBN2/SDCBP/SPI1/ACVRL1/CDKN1C/SMAD7	13
GO:0001960	negative regulation of cytokine-mediated signaling pathway	7/665	81/18722	0.0249369967689695	0.0962855954609172	ISG15/TREM2/OAS1/OAS3/CARD16/ECM1/USP18	7
GO:0048708	astrocyte differentiation	7/665	81/18722	0.0249369967689695	0.0962855954609172	VIM/TREM2/C5AR1/EGFR/GRN/S100A8/C1QA	7
GO:0051817	modulation of process of other organism involved in symbiotic interaction	7/665	81/18722	0.0249369967689695	0.0962855954609172	SAP30/APOE/IFI27/JUN/PHB/ZBED1/CFL1	7
GO:0071260	cellular response to mechanical stimulus	7/665	81/18722	0.0249369967689695	0.0962855954609172	SLC38A2/MYD88/BNIP3/RAC1/EGFR/PLEC/MAP3K2	7
GO:0034764	positive regulation of transmembrane transport	14/665	219/18722	0.0249528867109982	0.0962855954609172	TREM2/CALM1/ACSL1/GLRX/IRS2/RAP1A/FLNA/KCNE1/IFNGR2/PTAFR/WNK1/CALM3/KIF5B/EPHB2	14
GO:2001020	regulation of response to DNA damage stimulus	14/665	219/18722	0.0249528867109982	0.0962855954609172	CD74/MIF/CD44/IER3/TERF2IP/SKIL/MCL1/DTX3L/PARP9/EGFR/RPA2/ZNF385A/CXCL12/SETD2	14
GO:0010799	regulation of peptidyl-threonine phosphorylation	5/665	47/18722	0.02500015290073	0.0963184185400218	DDIT4/CALM1/CALM3/SMAD7/RIPK2	5
GO:0045581	negative regulation of T cell differentiation	5/665	47/18722	0.02500015290073	0.0963184185400218	CD74/FGL2/ANXA1/LAG3/SMAD7	5
GO:0007517	muscle organ development	19/665	327/18722	0.0250279255665205	0.0963507281685569	NUPR1/SAP30/YBX3/ATF3/VAMP5/LY6E/CITED2/FOS/RHOA/EGR1/PLEC/GPCPD1/COPS2/IGF2/RB1/NR4A1/SMAD7/MYL6/GPX1	19
GO:0006109	regulation of carbohydrate metabolic process	12/665	178/18722	0.0253592454264122	0.0974752125052349	NUPR1/DDIT4/FBP1/IRS2/PPP1CB/PPP1R3B/PTAFR/PHLDA2/PGAM1/PTK2B/IGF2/SCARB2	12
GO:0035265	organ growth	12/665	178/18722	0.0253592454264122	0.0974752125052349	YBX3/ECM1/HAMP/LY6E/CGA/CITED2/PTEN/RGS2/IGF2/JARID2/PSAP/DUSP6	12
GO:0032273	positive regulation of protein polymerization	10/665	138/18722	0.0254852805774995	0.0978839601778767	GSN/GMFG/ARPC4/MAPRE1/PYCARD/GRB2/RAC1/RHOA/PTK2B/IQGAP2	10
GO:0010039	response to iron ion	4/665	32/18722	0.0257823847462155	0.0982324315339075	B2M/HAMP/HMOX1/C1QA	4
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	4/665	32/18722	0.0257823847462155	0.0982324315339075	DAB2/CITED2/SDCBP/CDKN1C	4
GO:0035767	endothelial cell chemotaxis	4/665	32/18722	0.0257823847462155	0.0982324315339075	VEGFA/RAB13/NR4A1/NRP1	4
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	4/665	32/18722	0.0257823847462155	0.0982324315339075	TNFAIP3/PTEN/CDKN1A/CDKN1C	4
GO:0090022	regulation of neutrophil chemotaxis	4/665	32/18722	0.0257823847462155	0.0982324315339075	CD74/CXCL8/C5AR1/RAC1	4
GO:0090140	regulation of mitochondrial fission	4/665	32/18722	0.0257823847462155	0.0982324315339075	INF2/BNIP3/RALA/LRRK2	4
GO:1900745	positive regulation of p38MAPK cascade	4/665	32/18722	0.0257823847462155	0.0982324315339075	VEGFA/NCF1/MAP3K3/SPI1	4
GO:1901889	negative regulation of cell junction assembly	4/665	32/18722	0.0257823847462155	0.0982324315339075	PTEN/MMP14/ACVRL1/TLR2	4
GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	4/665	32/18722	0.0257823847462155	0.0982324315339075	DAB2/CITED2/SDCBP/CDKN1C	4
GO:0070542	response to fatty acid	6/665	64/18722	0.0257934251814385	0.0982324315339075	SCD/ACSL1/CD36/PTAFR/INSIG2/TLR2	6
GO:1903409	reactive oxygen species biosynthetic process	6/665	64/18722	0.0257934251814385	0.0982324315339075	PAGE4/ALOX5/SOD2/NCF1/CD36/RHOA	6
GO:0044706	multi-multicellular organism process	14/665	220/18722	0.0258162274782499	0.0982439897143199	VEGFA/CAPN2/TIMP1/ADM/FOSB/SLC38A2/NAMPT/JUNB/SMURF2/CITED2/FOS/RGS2/PTAFR/HEXB	14
GO:0046545	development of primary female sexual characteristics	8/665	100/18722	0.0259489282025147	0.0986734301197385	NUPR1/LHFPL2/VEGFA/CEBPB/ANG/IDH1/MMP14/TIPARP	8
GO:0071902	positive regulation of protein serine/threonine kinase activity	13/665	200/18722	0.0266717842344377	0.101344623581923	VEGFA/ADAM8/CALM1/ACSL1/CCNY/RHOA/DAZAP2/EGFR/LRRK2/CALM3/CAMK1/PTK2B/IGF2	13
GO:0002673	regulation of acute inflammatory response	5/665	48/18722	0.0271193848345112	0.102966648302155	FCGR2B/ADAM8/ALOX5AP/HLA-E/NLRP3	5
GO:0048638	regulation of developmental growth	19/665	330/18722	0.0271551894352084	0.103023886635867	CXCR4/VEGFA/APOE/YBX3/DPYSL2/HAMP/CGA/CITED2/PTEN/RGS2/CDKN1A/IGF2/FN1/AGRN/JARID2/CXCL12/SMAD7/DUSP6/NRP1	19
GO:0051897	positive regulation of protein kinase B signaling	9/665	120/18722	0.0272744988242047	0.103397604238213	ADAM8/HCLS1/EGFR/TXN/IGF2/PIK3CB/PHB/HAX1/GPX1	9
GO:0015909	long-chain fatty acid transport	6/665	65/18722	0.0275948755692812	0.104373311704207	PLIN2/APOE/ACSL1/CD36/IRS2/ANXA1	6
GO:0033692	cellular polysaccharide biosynthetic process	6/665	65/18722	0.0275948755692812	0.104373311704207	IRS2/PPP1CB/PPP1R3B/B3GNT7/PTGES3/IGF2	6
GO:0048524	positive regulation of viral process	6/665	65/18722	0.0275948755692812	0.104373311704207	IFIT1/HLA-DRB1/LGALS1/CD74/MDFIC/RSF1	6
GO:0043271	negative regulation of ion transport	11/665	160/18722	0.027767014210802	0.104944532796719	CALM1/HAMP/CLIC2/PTEN/KCNE1/RGS2/WNK1/CALM3/C4orf3/PTK2B/EPHB2	11
GO:0051899	membrane depolarization	7/665	83/18722	0.0280481746953641	0.105795973580975	YWHAH/JUN/IFI6/TSPO/LRRK2/SCN9A/SMAD7	7
GO:0002902	regulation of B cell apoptotic process	3/665	19/18722	0.0282903116477095	0.105795973580975	CD74/IRS2/PTEN	3
GO:0010885	regulation of cholesterol storage	3/665	19/18722	0.0282903116477095	0.105795973580975	TREM2/CD36/MSR1	3
GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling	3/665	19/18722	0.0282903116477095	0.105795973580975	TREM2/KLF4/PTEN	3
GO:0032616	interleukin-13 production	3/665	19/18722	0.0282903116477095	0.105795973580975	IL1RAP/LILRA5/HLA-E	3
GO:0032656	regulation of interleukin-13 production	3/665	19/18722	0.0282903116477095	0.105795973580975	IL1RAP/LILRA5/HLA-E	3
GO:0044827	modulation by host of viral genome replication	3/665	19/18722	0.0282903116477095	0.105795973580975	IFI27/PHB/ZBED1	3
GO:0045019	negative regulation of nitric oxide biosynthetic process	3/665	19/18722	0.0282903116477095	0.105795973580975	ACP5/DYNLL1/TSPO	3
GO:0045780	positive regulation of bone resorption	3/665	19/18722	0.0282903116477095	0.105795973580975	ADAM8/EGFR/TFRC	3
GO:0070233	negative regulation of T cell apoptotic process	3/665	19/18722	0.0282903116477095	0.105795973580975	TSC22D3/IL7R/DOCK8	3
GO:0070262	peptidyl-serine dephosphorylation	3/665	19/18722	0.0282903116477095	0.105795973580975	DUSP1/PPP1R15A/PPP2CB	3
GO:1903978	regulation of microglial cell activation	3/665	19/18722	0.0282903116477095	0.105795973580975	TREM2/LRRK2/GRN	3
GO:1904406	negative regulation of nitric oxide metabolic process	3/665	19/18722	0.0282903116477095	0.105795973580975	ACP5/DYNLL1/TSPO	3
GO:2000251	positive regulation of actin cytoskeleton reorganization	3/665	19/18722	0.0282903116477095	0.105795973580975	HCLS1/HAX1/NRP1	3
GO:1905952	regulation of lipid localization	12/665	181/18722	0.0283882584502598	0.10607071474336	PLIN2/TREM2/APOE/APOC1/NFKBIA/ACSL1/TSPO/CD36/IRS2/MSR1/ANXA2/ABHD5	12
GO:0002431	Fc receptor mediated stimulatory signaling pathway	4/665	33/18722	0.0285393192957189	0.10607071474336	FCGR2B/MYO1G/PLSCR1/RAP1A	4
GO:0034110	regulation of homotypic cell-cell adhesion	4/665	33/18722	0.0285393192957189	0.10607071474336	LGALS1/CD9/PDPN/PLAUR	4
GO:0050901	leukocyte tethering or rolling	4/665	33/18722	0.0285393192957189	0.10607071474336	PTAFR/SELPLG/GCNT1/CXCL12	4
GO:0070570	regulation of neuron projection regeneration	4/665	33/18722	0.0285393192957189	0.10607071474336	KLF4/PTEN/FLNA/GRN	4
GO:1903146	regulation of autophagy of mitochondrion	4/665	33/18722	0.0285393192957189	0.10607071474336	BNIP3L/TSPO/BNIP3/HAX1	4
GO:1903715	regulation of aerobic respiration	4/665	33/18722	0.0285393192957189	0.10607071474336	NUPR1/BNIP3/DNAJC15/RHOA	4
GO:1904030	negative regulation of cyclin-dependent protein kinase activity	4/665	33/18722	0.0285393192957189	0.10607071474336	TNFAIP3/PTEN/CDKN1A/CDKN1C	4
GO:0038127	ERBB signaling pathway	9/665	121/18722	0.0285772006119435	0.10607071474336	IFI6/ERRFI1/NCF1/GRB2/RASSF2/PTPN12/EGFR/PLAUR/PTK2B	9
GO:0043500	muscle adaptation	9/665	121/18722	0.0285772006119435	0.10607071474336	KLF4/ERRFI1/GSN/HAMP/HMOX1/RGS2/LMNA/GATM/JARID2	9
GO:0051047	positive regulation of secretion	18/665	310/18722	0.0287847485899254	0.106761343650693	HLA-DRB1/TREM2/ADAM8/GLUL/DYNLL1/HLA-F/IRS2/ANG/RAC1/ITGAM/EGFR/PTAFR/SDCBP/S100A8/KIF5B/KMO/TLR2/CXCL12	18
GO:0035296	regulation of tube diameter	10/665	141/18722	0.0290100383550791	0.107436580197275	APOE/ADM/SOD2/DOCK4/KLF2/RHOA/RGS2/EGFR/KCNMA1/GPX1	10
GO:0097746	blood vessel diameter maintenance	10/665	141/18722	0.0290100383550791	0.107436580197275	APOE/ADM/SOD2/DOCK4/KLF2/RHOA/RGS2/EGFR/KCNMA1/GPX1	10
GO:0018198	peptidyl-cysteine modification	5/665	49/18722	0.0293495645138982	0.108532243775353	GAPDH/ZDHHC20/GOLGA7/S100A8/TXN	5
GO:0030195	negative regulation of blood coagulation	5/665	49/18722	0.0293495645138982	0.108532243775353	CD9/APOE/SERPING1/PLAU/ANXA2	5
GO:0010660	regulation of muscle cell apoptotic process	7/665	84/18722	0.0296981694627659	0.109739704260183	NUPR1/CAPN2/SOD2/BNIP3/PTEN/HMOX1/PTK2B	7
GO:0034250	positive regulation of cellular amide metabolic process	11/665	162/18722	0.0300430677693543	0.110931684111212	VIM/PKM/YBX3/PPP1R15A/RPS27L/CNBP/RHOA/PTAFR/PTK2B/TOB1/ELAVL1	11
GO:0035150	regulation of tube size	10/665	142/18722	0.0302582087836686	0.111643131146869	APOE/ADM/SOD2/DOCK4/KLF2/RHOA/RGS2/EGFR/KCNMA1/GPX1	10
GO:0008037	cell recognition	14/665	225/18722	0.0304678596364162	0.112333280706965	CXCR4/TREM2/CD9/VCAN/ALDOA/CLEC7A/CD36/CADM1/LGALS3/MSN/DOCK8/EPHB2/CD81/NRP1	14
GO:0006690	icosanoid metabolic process	9/665	123/18722	0.0313123121909816	0.115069536334483	CD74/ALOX5/MIF/ALOX5AP/ANXA1/PTGES3/CYP1B1/TLR2/GPX1	9
GO:0071277	cellular response to calcium ion	7/665	85/18722	0.0314123542252874	0.115069536334483	JUND/FOSB/JUNB/ALOX5AP/FOS/WNK1/CACYBP	7
GO:0072665	protein localization to vacuole	6/665	67/18722	0.0314425135892431	0.115069536334483	TNFAIP3/GBP1/LAMTOR5/SCARB2/VPS13A/CD81	6
GO:0009649	entrainment of circadian clock	4/665	34/18722	0.0314646881043386	0.115069536334483	GNAQ/BHLHE40/PPP1CB/PER1	4
GO:0010614	negative regulation of cardiac muscle hypertrophy	4/665	34/18722	0.0314646881043386	0.115069536334483	ERRFI1/RGS2/LMNA/JARID2	4
GO:0010661	positive regulation of muscle cell apoptotic process	4/665	34/18722	0.0314646881043386	0.115069536334483	CAPN2/SOD2/BNIP3/PTEN	4
GO:0010922	positive regulation of phosphatase activity	4/665	34/18722	0.0314646881043386	0.115069536334483	CD300A/CALM1/PPP1R15A/CALM3	4
GO:0014072	response to isoquinoline alkaloid	4/665	34/18722	0.0314646881043386	0.115069536334483	CXCR4/FOSB/PEA15/GPI	4
GO:0043278	response to morphine	4/665	34/18722	0.0314646881043386	0.115069536334483	CXCR4/FOSB/PEA15/GPI	4
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	4/665	34/18722	0.0314646881043386	0.115069536334483	CD74/MIF/CD44/ZNF385A	4
GO:0048261	negative regulation of receptor-mediated endocytosis	4/665	34/18722	0.0314646881043386	0.115069536334483	APOC1/RIN3/RAC1/SDCBP	4
GO:0043268	positive regulation of potassium ion transport	5/665	50/18722	0.0316921495911936	0.115646096525868	TREM2/FLNA/KCNE1/WNK1/KIF5B	5
GO:0070231	T cell apoptotic process	5/665	50/18722	0.0316921495911936	0.115646096525868	TSC22D3/ADAM8/LGALS3/IL7R/DOCK8	5
GO:1900047	negative regulation of hemostasis	5/665	50/18722	0.0316921495911936	0.115646096525868	CD9/APOE/SERPING1/PLAU/ANXA2	5
GO:0022600	digestive system process	8/665	104/18722	0.0318206401755868	0.115859766793162	SLC2A5/SGK1/TYMP/SNX10/CD36/HAMP/EPB41/WNK1	8
GO:0048661	positive regulation of smooth muscle cell proliferation	8/665	104/18722	0.0318206401755868	0.115859766793162	JUN/STAT1/NAMPT/MYD88/HMOX1/EGFR/PTAFR/PHB	8
GO:1901890	positive regulation of cell junction assembly	8/665	104/18722	0.0318206401755868	0.115859766793162	VEGFA/LIMS1/IL1RAP/S100A10/RAC1/EPHB2/AGRN/NRP1	8
GO:0006605	protein targeting	18/665	314/18722	0.0320888607404561	0.116750833001513	NCF1/BNIP3L/TSPO/SEC61G/ZDHHC20/GOLGA7/DNAJC15/ITGAM/KCNE1/LRRK2/SDCBP/TIMM8B/ATG3/SCARB2/HAX1/TIMM10/VPS13A/PRNP	18
GO:0002834	regulation of response to tumor cell	3/665	20/18722	0.0324261799471091	0.117205901336096	HLA-DRB1/IL4I1/AHR	3
GO:0002837	regulation of immune response to tumor cell	3/665	20/18722	0.0324261799471091	0.117205901336096	HLA-DRB1/IL4I1/AHR	3
GO:0006700	C21-steroid hormone biosynthetic process	3/665	20/18722	0.0324261799471091	0.117205901336096	ADM/TSPO/EGR1	3
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	3/665	20/18722	0.0324261799471091	0.117205901336096	TYMP/UPP1/CMPK1	3
GO:0010042	response to manganese ion	3/665	20/18722	0.0324261799471091	0.117205901336096	SOD2/TSPO/LRRK2	3
GO:0010523	negative regulation of calcium ion transport into cytosol	3/665	20/18722	0.0324261799471091	0.117205901336096	CALM1/CLIC2/CALM3	3
GO:0051004	regulation of lipoprotein lipase activity	3/665	20/18722	0.0324261799471091	0.117205901336096	APOC1/ANGPTL4/ABHD5	3
GO:0051900	regulation of mitochondrial depolarization	3/665	20/18722	0.0324261799471091	0.117205901336096	IFI6/TSPO/LRRK2	3
GO:0060044	negative regulation of cardiac muscle cell proliferation	3/665	20/18722	0.0324261799471091	0.117205901336096	CITED2/PTEN/JARID2	3
GO:0045137	development of primary sexual characteristics	14/665	227/18722	0.0324902357764965	0.117352087070631	NUPR1/LHFPL2/VEGFA/CEBPB/YBX3/HSD17B4/ANG/IDH1/CGA/CITED2/FLNA/MMP14/RAB13/TIPARP	14
GO:0032413	negative regulation of ion transmembrane transporter activity	7/665	86/18722	0.0331916124905299	0.119798339925878	CALM1/CLIC2/PTEN/KCNE1/CALM3/C4orf3/EPHB2	7
GO:0009988	cell-cell recognition	6/665	68/18722	0.0334909683478686	0.120454286274131	CD9/ALDOA/LGALS3/MSN/DOCK8/CD81	6
GO:0010812	negative regulation of cell-substrate adhesion	6/665	68/18722	0.0334909683478686	0.120454286274131	LGALS1/PTEN/GBP1/RHOA/MMP14/ACVRL1	6
GO:0032922	circadian regulation of gene expression	6/665	68/18722	0.0334909683478686	0.120454286274131	AHR/BHLHE40/NAMPT/PPP1CB/EGR1/PER1	6
GO:0001655	urogenital system development	19/665	338/18722	0.0334945319176759	0.120454286274131	VEGFA/CTSH/SULF2/STAT1/CRIP1/PTEN/PRKX/ANXA1/RRM2B/RHOA/EGR1/LRRK2/APH1A/GCNT1/EPHB2/TIPARP/SMAD7/PSAP/NRP1	19
GO:0018209	peptidyl-serine modification	19/665	338/18722	0.0334945319176759	0.120454286274131	VEGFA/DDIT4/SGK1/MIF/CD44/TERF2IP/RASSF2/PTEN/PRKX/HCLS1/EGFR/LRRK2/WNK1/TXN/CAMK1/TFRC/HAX1/SMAD7/RIPK2	19
GO:0071560	cellular response to transforming growth factor beta stimulus	15/665	250/18722	0.0339510335303579	0.122007690994851	LIMS1/JUN/ZFP36L2/DAB2/SKIL/SMURF2/CITED2/PEG10/FOS/FBN2/SDCBP/SPI1/ACVRL1/CDKN1C/SMAD7	15
GO:0071478	cellular response to radiation	12/665	186/18722	0.0340059933553909	0.122028727058695	TIMP1/CRIP1/CARD16/HAMP/NAMPT/N4BP1/GRB2/EGR1/RHOB/TANK/CDKN1A/XPC	12
GO:1902115	regulation of organelle assembly	12/665	186/18722	0.0340059933553909	0.122028727058695	NUPR1/IL1RAP/GSN/PIP4K2A/MSN/RHOA/LRRK2/SDCBP/ABI3/ATG3/RNF5/CHMP5	12
GO:0006636	unsaturated fatty acid biosynthetic process	5/665	51/18722	0.0341484339609687	0.122363169997127	CD74/SCD/MIF/ANXA1/PTGES3	5
GO:0046850	regulation of bone remodeling	5/665	51/18722	0.0341484339609687	0.122363169997127	ADAM8/HAMP/TNFAIP3/EGFR/TFRC	5
GO:0045454	cell redox homeostasis	4/665	35/18722	0.0345596726371793	0.123743728060266	SLC11A1/ERO1A/TXN/GPX1	4
GO:0001649	osteoblast differentiation	14/665	229/18722	0.0346084068418047	0.123743728060266	JUND/IFITM1/GPNMB/VCAN/CEBPB/HSD17B4/JUNB/CLIC1/RASSF2/HIF1A-AS2/FBN2/IGF2/TOB1/PHB	14
GO:0071695	anatomical structure maturation	14/665	229/18722	0.0346084068418047	0.123743728060266	VEGFA/CLEC7A/SNX10/NR4A2/ANG/KLF2/RHOA/LRRK2/CDKN1A/ACVRL1/PTK2B/RB1/AGRN/C1QA	14
GO:0150104	transport across blood-brain barrier	7/665	87/18722	0.0350367814095292	0.124951638703632	APOE/SLC1A3/CD36/SLC38A2/SLC2A3/ABCC3/TFRC	7
GO:1900182	positive regulation of protein localization to nucleus	7/665	87/18722	0.0350367814095292	0.124951638703632	DTX3L/PARP9/FLNA/HCLS1/LAMTOR5/LARP7/TFRC	7
GO:0001824	blastocyst development	8/665	106/18722	0.035071938831301	0.124951638703632	CAPN2/KLF4/SKIL/JUNB/CITED2/COPS2/SF3B6/SMIM14	8
GO:0002793	positive regulation of peptide secretion	8/665	106/18722	0.035071938831301	0.124951638703632	HLA-DRB1/GLUL/DYNLL1/IRS2/RAC1/EGFR/S100A8/KIF5B	8
GO:0035821	modulation of process of other organism	8/665	106/18722	0.035071938831301	0.124951638703632	SAP30/APOE/IFI27/JUN/CLEC7A/PHB/ZBED1/CFL1	8
GO:0045669	positive regulation of osteoblast differentiation	6/665	69/18722	0.0356238886032285	0.126579141157046	JUND/IFITM1/CEBPB/CLIC1/HIF1A-AS2/FBN2	6
GO:0050810	regulation of steroid biosynthetic process	6/665	69/18722	0.0356238886032285	0.126579141157046	APOE/ADM/TSPO/CGA/EGR1/INSIG2	6
GO:0051966	regulation of synaptic transmission, glutamatergic	6/665	69/18722	0.0356238886032285	0.126579141157046	GLUL/EGFR/LRRK2/TPRG1L/PTK2B/KMO	6
GO:0048813	dendrite morphogenesis	10/665	146/18722	0.0356306274605045	0.126579141157046	YWHAH/TANC2/ABI1/PTEN/LRRK2/ABI3/EPHB2/CFL1/SIPA1L1/NRP1	10
GO:0045055	regulated exocytosis	14/665	230/18722	0.0357040956789026	0.126749539660104	FCGR2B/CD300A/CALM1/HLA-F/RAP1A/HMOX1/ITGAM/PTAFR/LRRK2/CALM3/STX3/SPI1/SYNGR2/RAB31	14
GO:0050890	cognition	17/665	296/18722	0.0359647579223842	0.127583759367773	HLA-DRA/TREM2/B2M/APOE/JUN/SGK1/CEBPB/C5AR1/PTEN/FOS/GPI/EGFR/GATM/UBA6/EPHB2/TLR2/PRNP	17
GO:0034767	positive regulation of ion transmembrane transport	11/665	167/18722	0.0363107269026763	0.128643857512934	TREM2/CALM1/GLRX/FLNA/KCNE1/IFNGR2/PTAFR/WNK1/CALM3/KIF5B/EPHB2	11
GO:0021545	cranial nerve development	5/665	52/18722	0.0367195472325287	0.128643857512934	SLC1A3/MAFB/CITED2/EPHB2/NRP1	5
GO:0030514	negative regulation of BMP signaling pathway	5/665	52/18722	0.0367195472325287	0.128643857512934	SKIL/SMURF2/UBE2D1/TOB1/SMAD7	5
GO:0031103	axon regeneration	5/665	52/18722	0.0367195472325287	0.128643857512934	KLF4/TSPO/PTEN/FLNA/GRN	5
GO:0043392	negative regulation of DNA binding	5/665	52/18722	0.0367195472325287	0.128643857512934	JUN/NFKBIA/HMOX1/SUMO3/RSF1	5
GO:0051496	positive regulation of stress fiber assembly	5/665	52/18722	0.0367195472325287	0.128643857512934	S100A10/RAC1/RHOA/RHOC/NRP1	5
GO:1903426	regulation of reactive oxygen species biosynthetic process	5/665	52/18722	0.0367195472325287	0.128643857512934	PAGE4/ALOX5/SOD2/CD36/RHOA	5
GO:2000378	negative regulation of reactive oxygen species metabolic process	5/665	52/18722	0.0367195472325287	0.128643857512934	PAGE4/HK2/ACP5/BNIP3/RHOA	5
GO:0051341	regulation of oxidoreductase activity	8/665	107/18722	0.0367788617124744	0.128643857512934	APOE/CALM1/DDAH2/EGFR/LRRK2/CALM3/PTK2B/PIK3CB	8
GO:0002689	negative regulation of leukocyte chemotaxis	3/665	21/18722	0.0368589241646717	0.128643857512934	DUSP1/MIF/RIN3	3
GO:0006925	inflammatory cell apoptotic process	3/665	21/18722	0.0368589241646717	0.128643857512934	IRF7/ANXA1/PIK3CB	3
GO:0030449	regulation of complement activation	3/665	21/18722	0.0368589241646717	0.128643857512934	TREM2/SERPING1/PHB	3
GO:0030502	negative regulation of bone mineralization	3/665	21/18722	0.0368589241646717	0.128643857512934	SRGN/ECM1/PTK2B	3
GO:0034035	purine ribonucleoside bisphosphate metabolic process	3/665	21/18722	0.0368589241646717	0.128643857512934	PAPSS1/PAPSS2/ABHD14B	3
GO:0038083	peptidyl-tyrosine autophosphorylation	3/665	21/18722	0.0368589241646717	0.128643857512934	VEGFA/EGFR/PTK2B	3
GO:0044766	multi-organism transport	3/665	21/18722	0.0368589241646717	0.128643857512934	IFIT1/BST2/KPNA3	3
GO:0046823	negative regulation of nucleocytoplasmic transport	3/665	21/18722	0.0368589241646717	0.128643857512934	CD36/TXN/MDFIC	3
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	3/665	21/18722	0.0368589241646717	0.128643857512934	PAPSS1/PAPSS2/ABHD14B	3
GO:0071605	monocyte chemotactic protein-1 production	3/665	21/18722	0.0368589241646717	0.128643857512934	OAS1/OAS3/CLEC7A	3
GO:0071637	regulation of monocyte chemotactic protein-1 production	3/665	21/18722	0.0368589241646717	0.128643857512934	OAS1/OAS3/CLEC7A	3
GO:0098698	postsynaptic specialization assembly	3/665	21/18722	0.0368589241646717	0.128643857512934	IL1RAP/PTEN/ABI3	3
GO:1902307	positive regulation of sodium ion transmembrane transport	3/665	21/18722	0.0368589241646717	0.128643857512934	GLRX/WNK1/KIF5B	3
GO:1902579	multi-organism localization	3/665	21/18722	0.0368589241646717	0.128643857512934	IFIT1/BST2/KPNA3	3
GO:0010232	vascular transport	7/665	88/18722	0.0369486506481159	0.128776152679618	APOE/SLC1A3/CD36/SLC38A2/SLC2A3/ABCC3/TFRC	7
GO:0050829	defense response to Gram-negative bacterium	7/665	88/18722	0.0369486506481159	0.128776152679618	SLC11A1/TREM2/RNASE6/LYZ/TREM1/PYCARD/TNFRSF14	7
GO:0006911	phagocytosis, engulfment	9/665	127/18722	0.0373178812126178	0.129971877804282	FCGR2B/TREM2/CD300A/CD36/GSN/MSR1/RAC1/ITGAM/RAB31	9
GO:0009416	response to light stimulus	18/665	320/18722	0.0375612941264642	0.130728033479361	JUND/DUSP1/TIMP1/CRIP1/SLC1A3/CARD16/GNAQ/BHLHE40/UBE2B/N4BP1/PPP1CB/FOS/EGFR/CDKN1A/DYNLRB1/PER1/XPC/GPX1	18
GO:1902806	regulation of cell cycle G1/S phase transition	11/665	168/18722	0.0376665357164924	0.131002576984582	GPNMB/KLF4/PSME2/RPS27L/PTEN/ANXA1/EGFR/RPA2/PLK3/CDKN1A/RB1	11
GO:0002691	regulation of cellular extravasation	4/665	36/18722	0.0378250721990647	0.131186747264027	ADAM8/PTAFR/IL27RA/CXCL12	4
GO:0014741	negative regulation of muscle hypertrophy	4/665	36/18722	0.0378250721990647	0.131186747264027	ERRFI1/RGS2/LMNA/JARID2	4
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	4/665	36/18722	0.0378250721990647	0.131186747264027	HLA-DRB1/DYNLL1/RAC1/KIF5B	4
GO:0038179	neurotrophin signaling pathway	4/665	36/18722	0.0378250721990647	0.131186747264027	DDIT4/RAP1A/RAPGEF1/AKT1S1	4
GO:0043491	protein kinase B signaling	13/665	211/18722	0.0386409636695302	0.133923005186586	ADAM8/KLF4/MERTK/PTEN/HCLS1/EGFR/PLK3/TXN/IGF2/PIK3CB/PHB/HAX1/GPX1	13
GO:0010657	muscle cell apoptotic process	7/665	89/18722	0.0389279613534939	0.134750763764294	NUPR1/CAPN2/SOD2/BNIP3/PTEN/HMOX1/PTK2B	7
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	9/665	128/18722	0.0389340234940696	0.134750763764294	DAB2/SKIL/SMURF2/CITED2/PEG10/FBN2/SDCBP/CDKN1C/SMAD7	9
GO:0006937	regulation of muscle contraction	11/665	169/18722	0.039057340341824	0.135083494432056	CALM1/CLIC2/ENO1/DOCK4/RHOA/RGS2/PTAFR/CALM3/KCNMA1/NR4A1/SMAD7	11
GO:0007611	learning or memory	15/665	255/18722	0.0393194769272825	0.135536387464989	TREM2/B2M/APOE/JUN/SGK1/CEBPB/PTEN/FOS/GPI/EGFR/GATM/UBA6/EPHB2/TLR2/PRNP	15
GO:0016925	protein sumoylation	5/665	53/18722	0.0394064547056154	0.135536387464989	IFIH1/SUMO2/EGR1/SUMO3/ZBED1	5
GO:0043113	receptor clustering	5/665	53/18722	0.0394064547056154	0.135536387464989	APOE/GSN/FLNA/AGRN/CD81	5
GO:0050819	negative regulation of coagulation	5/665	53/18722	0.0394064547056154	0.135536387464989	CD9/APOE/SERPING1/PLAU/ANXA2	5
GO:0071320	cellular response to cAMP	5/665	53/18722	0.0394064547056154	0.135536387464989	AHR/RAP1A/RAPGEF1/KCNE1/PTAFR	5
GO:0097479	synaptic vesicle localization	5/665	53/18722	0.0394064547056154	0.135536387464989	BLOC1S1/PTEN/BLOC1S2/LRRK2/KIF5B	5
GO:1903202	negative regulation of oxidative stress-induced cell death	5/665	53/18722	0.0394064547056154	0.135536387464989	PAGE4/SOD2/LRRK2/TXN/GPX1	5
GO:2000772	regulation of cellular senescence	5/665	53/18722	0.0394064547056154	0.135536387464989	B2M/NAMPT/YBX1/MAP3K3/ABI3	5
GO:0043550	regulation of lipid kinase activity	6/665	71/18722	0.0401467485357178	0.13798709558957	KLF4/PIP4K2A/SOCS3/PTK2B/RB1/CD81	6
GO:0006821	chloride transport	8/665	109/18722	0.0403583690222702	0.138618586068198	SLC1A3/TSPO/CLIC2/CLIC1/GABRB2/PTAFR/TTYH3/PRNP	8
GO:0034976	response to endoplasmic reticulum stress	15/665	256/18722	0.0404622770094993	0.13878365544321	FCGR2B/NUPR1/JUN/EIF2AK2/ALOX5/CXCL8/CEBPB/ERO1A/ATF3/PPP1R15A/PPP2CB/LRRK2/PSMC6/RNF5/GRINA	15
GO:0071559	response to transforming growth factor beta	15/665	256/18722	0.0404622770094993	0.13878365544321	LIMS1/JUN/ZFP36L2/DAB2/SKIL/SMURF2/CITED2/PEG10/FOS/FBN2/SDCBP/SPI1/ACVRL1/CDKN1C/SMAD7	15
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	7/665	90/18722	0.040975405216013	0.140446733740403	DAB2/SUMO2/TRIB1/RBX1/LRRK2/PLK3/SMAD7	7
GO:0032885	regulation of polysaccharide biosynthetic process	4/665	37/18722	0.0412613148174364	0.140940711094611	IRS2/PPP1CB/PPP1R3B/IGF2	4
GO:0043403	skeletal muscle tissue regeneration	4/665	37/18722	0.0412613148174364	0.140940711094611	CD9/ANXA1/CD81/GPX1	4
GO:0043687	post-translational protein modification	4/665	37/18722	0.0412613148174364	0.140940711094611	RBX1/UBE2F/WIPI2/FAM20C	4
GO:0048846	axon extension involved in axon guidance	4/665	37/18722	0.0412613148174364	0.140940711094611	ALCAM/VEGFA/CXCL12/NRP1	4
GO:1902284	neuron projection extension involved in neuron projection guidance	4/665	37/18722	0.0412613148174364	0.140940711094611	ALCAM/VEGFA/CXCL12/NRP1	4
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	3/665	22/18722	0.0415848401211862	0.140979983221211	CALM1/CLIC2/CALM3	3
GO:0032816	positive regulation of natural killer cell activation	3/665	22/18722	0.0415848401211862	0.140979983221211	HLA-F/HLA-E/TYROBP	3
GO:0034755	iron ion transmembrane transport	3/665	22/18722	0.0415848401211862	0.140979983221211	SLC11A1/SLC25A37/HAMP	3
GO:0050860	negative regulation of T cell receptor signaling pathway	3/665	22/18722	0.0415848401211862	0.140979983221211	LGALS3/GBP1/PRNP	3
GO:0055093	response to hyperoxia	3/665	22/18722	0.0415848401211862	0.140979983221211	BNIP3/PDPN/CDKN1A	3
GO:0071404	cellular response to low-density lipoprotein particle stimulus	3/665	22/18722	0.0415848401211862	0.140979983221211	CD9/CD36/CD81	3
GO:0072574	hepatocyte proliferation	3/665	22/18722	0.0415848401211862	0.140979983221211	SULF2/CEBPB/TNFAIP3	3
GO:0072575	epithelial cell proliferation involved in liver morphogenesis	3/665	22/18722	0.0415848401211862	0.140979983221211	SULF2/CEBPB/TNFAIP3	3
GO:1900543	negative regulation of purine nucleotide metabolic process	3/665	22/18722	0.0415848401211862	0.140979983221211	NUPR1/DDIT4/FBP1	3
GO:2000114	regulation of establishment of cell polarity	3/665	22/18722	0.0415848401211862	0.140979983221211	GSN/PTK2B/DOCK8	3
GO:2000773	negative regulation of cellular senescence	3/665	22/18722	0.0415848401211862	0.140979983221211	NAMPT/YBX1/MAP3K3	3
GO:0050804	modulation of chemical synaptic transmission	23/665	439/18722	0.0416291561627731	0.141034019174494	SRGN/APOE/YWHAH/CALM1/GLUL/SLC1A3/RAB8A/RAP1A/PTEN/EGFR/LRRK2/TPRG1L/CALM3/KIF5B/STX3/PTK2B/SQSTM1/TYROBP/EIF4E/EPHB2/KMO/SIPA1L1/PRNP	23
GO:0006936	muscle contraction	19/665	347/18722	0.0418701854638659	0.141718964091591	CXCR4/SULF2/SLC6A8/CALM1/ALDOA/GSN/CLIC2/ENO1/DOCK4/FLNA/KCNE1/RHOA/RGS2/PTAFR/CALM3/KCNMA1/NR4A1/SMAD7/MYL6	19
GO:0046890	regulation of lipid biosynthetic process	11/665	171/18722	0.0419453915852576	0.141718964091591	APOE/CAPN2/APOC1/CD74/ADM/TSPO/IDH1/CGA/ANXA1/EGR1/INSIG2	11
GO:0048469	cell maturation	11/665	171/18722	0.0419453915852576	0.141718964091591	VEGFA/CLEC7A/NR4A2/ANG/KLF2/LRRK2/CDKN1A/PTK2B/RB1/AGRN/C1QA	11
GO:0051048	negative regulation of secretion	11/665	171/18722	0.0419453915852576	0.141718964091591	FCGR2B/APOE/CD300A/CD74/RSAD2/HLA-F/RAP1A/HMOX1/ANXA1/WNK1/SPI1	11
GO:0001706	endoderm formation	5/665	54/18722	0.0422099578218688	0.142397263454638	DUSP1/MMP14/FN1/DUSP2/SETD2	5
GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	5/665	54/18722	0.0422099578218688	0.142397263454638	JUN/KLF4/FOS/EGR1/SPI1	5
GO:1905954	positive regulation of lipid localization	8/665	110/18722	0.0422321059018384	0.142397263454638	PLIN2/TREM2/APOE/NFKBIA/ACSL1/CD36/MSR1/ANXA2	8
GO:0000082	G1/S transition of mitotic cell cycle	13/665	214/18722	0.0424778638734007	0.14275171226959	GPNMB/KLF4/PSME2/RPS27L/PTEN/ANXA1/EIF4EBP1/EGFR/RPA2/PLK3/CDKN1A/RB1/EIF4E	13
GO:0072330	monocarboxylic acid biosynthetic process	13/665	214/18722	0.0424778638734007	0.14275171226959	APOC1/CD74/ALOX5/SCD/MIF/ANXA1/PTGES3/RBP1/OSBPL1A/GATM/INSIG2/HACD4/KMO	13
GO:0099177	regulation of trans-synaptic signaling	23/665	440/18722	0.0425222001741763	0.14275171226959	SRGN/APOE/YWHAH/CALM1/GLUL/SLC1A3/RAB8A/RAP1A/PTEN/EGFR/LRRK2/TPRG1L/CALM3/KIF5B/STX3/PTK2B/SQSTM1/TYROBP/EIF4E/EPHB2/KMO/SIPA1L1/PRNP	23
GO:0000271	polysaccharide biosynthetic process	6/665	72/18722	0.0425382868956263	0.14275171226959	IRS2/PPP1CB/PPP1R3B/B3GNT7/PTGES3/IGF2	6
GO:0005977	glycogen metabolic process	6/665	72/18722	0.0425382868956263	0.14275171226959	IRS2/PPP1CB/PPP1R3B/PTGES3/PHLDA2/IGF2	6
GO:0042246	tissue regeneration	6/665	72/18722	0.0425382868956263	0.14275171226959	CD9/ANXA1/PTPN12/CDKN1A/CD81/GPX1	6
GO:1903036	positive regulation of response to wounding	6/665	72/18722	0.0425382868956263	0.14275171226959	CXCR4/CLEC7A/CD36/ANXA1/FLNA/GRN	6
GO:0007565	female pregnancy	12/665	193/18722	0.0431414338680573	0.144678087938087	VEGFA/CAPN2/TIMP1/ADM/FOSB/SLC38A2/NAMPT/JUNB/SMURF2/CITED2/FOS/RGS2	12
GO:0043535	regulation of blood vessel endothelial cell migration	10/665	151/18722	0.0432353166896835	0.144797522875827	VEGFA/APOE/KLF4/CSNK2B/HMOX1/ANXA1/RHOA/MAP3K3/ACVRL1/NRP1	10
GO:1904064	positive regulation of cation transmembrane transport	10/665	151/18722	0.0432353166896835	0.144797522875827	TREM2/CALM1/GLRX/FLNA/KCNE1/IFNGR2/WNK1/CALM3/KIF5B/EPHB2	10
GO:0006470	protein dephosphorylation	16/665	281/18722	0.0437386858963273	0.146384692865149	CD300A/DUSP1/CALM1/CSNK2B/PPP1R15A/LGALS3/PPP1CB/PPP1R3B/PTP4A2/PTEN/PPP2CB/PTPN12/LRRK2/CALM3/DUSP18/DUSP6	16
GO:0006612	protein targeting to membrane	9/665	131/18722	0.0440658716478401	0.147281359845168	NCF1/SEC61G/ZDHHC20/GOLGA7/ITGAM/KCNE1/SDCBP/ATG3/PRNP	9
GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	9/665	131/18722	0.0440658716478401	0.147281359845168	DAB2/SKIL/SMURF2/CITED2/PEG10/FBN2/SDCBP/CDKN1C/SMAD7	9
GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	8/665	111/18722	0.0441625464485944	0.14750527946876	TREM2/KLF4/NCF1/PTEN/HCLS1/EGFR/FN1/HAX1	8
GO:0001825	blastocyst formation	4/665	38/18722	0.0448684689789699	0.149096854290174	SKIL/JUNB/CITED2/SF3B6	4
GO:0030279	negative regulation of ossification	4/665	38/18722	0.0448684689789699	0.149096854290174	SRGN/ECM1/PTK2B/SMAD7	4
GO:0032373	positive regulation of sterol transport	4/665	38/18722	0.0448684689789699	0.149096854290174	TREM2/APOE/NFKBIA/ANXA2	4
GO:0032376	positive regulation of cholesterol transport	4/665	38/18722	0.0448684689789699	0.149096854290174	TREM2/APOE/NFKBIA/ANXA2	4
GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway	4/665	38/18722	0.0448684689789699	0.149096854290174	DAB2/RHOA/PHB/PER1	4
GO:0048246	macrophage chemotaxis	4/665	38/18722	0.0448684689789699	0.149096854290174	C5AR1/MIF/LGALS3/PTK2B	4
GO:2000279	negative regulation of DNA biosynthetic process	4/665	38/18722	0.0448684689789699	0.149096854290174	DUSP1/CDKN1A/ACVRL1/HNRNPA1	4
GO:0050871	positive regulation of B cell activation	10/665	152/18722	0.0448790531223542	0.149096854290174	GPR183/CD74/TNFSF13B/MIF/IRS2/MMP14/CDKN1A/TFRC/EPHB2/CD81	10
GO:0006073	cellular glucan metabolic process	6/665	73/18722	0.0450174866055892	0.149234567179608	IRS2/PPP1CB/PPP1R3B/PTGES3/PHLDA2/IGF2	6
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	6/665	73/18722	0.0450174866055892	0.149234567179608	IFI6/ERRFI1/NCF1/PTPN12/EGFR/PLAUR	6
GO:0044042	glucan metabolic process	6/665	73/18722	0.0450174866055892	0.149234567179608	IRS2/PPP1CB/PPP1R3B/PTGES3/PHLDA2/IGF2	6
GO:0044091	membrane biogenesis	5/665	55/18722	0.0451306950645776	0.149234567179608	S100A10/PTEN/SERINC1/ANXA2/EPHB2	5
GO:0045620	negative regulation of lymphocyte differentiation	5/665	55/18722	0.0451306950645776	0.149234567179608	CD74/FGL2/ANXA1/LAG3/SMAD7	5
GO:0061614	pri-miRNA transcription by RNA polymerase II	5/665	55/18722	0.0451306950645776	0.149234567179608	JUN/KLF4/FOS/EGR1/SPI1	5
GO:0098900	regulation of action potential	5/665	55/18722	0.0451306950645776	0.149234567179608	CALM1/CD36/FLNA/CALM3/KCNAB2	5
GO:0009141	nucleoside triphosphate metabolic process	8/665	112/18722	0.0461501857804759	0.149877356992938	TREM2/ALDOA/CMPK1/ENO1/RRM2B/RHOA/LRRK2/GUK1	8
GO:0002082	regulation of oxidative phosphorylation	3/665	23/18722	0.0465993149461045	0.149877356992938	NUPR1/DNAJC15/RHOA	3
GO:0009162	deoxyribonucleoside monophosphate metabolic process	3/665	23/18722	0.0465993149461045	0.149877356992938	TYMP/UPP1/GUK1	3
GO:0010888	negative regulation of lipid storage	3/665	23/18722	0.0465993149461045	0.149877356992938	TREM2/NFKBIA/ABHD5	3
GO:0030325	adrenal gland development	3/665	23/18722	0.0465993149461045	0.149877356992938	TSPO/LY6E/CITED2	3
GO:0031338	regulation of vesicle fusion	3/665	23/18722	0.0465993149461045	0.149877356992938	ANXA1/KIF5B/ANXA2	3
GO:0033081	regulation of T cell differentiation in thymus	3/665	23/18722	0.0465993149461045	0.149877356992938	ADAM8/IL7R/SOS2	3
GO:0036303	lymph vessel morphogenesis	3/665	23/18722	0.0465993149461045	0.149877356992938	VEGFA/PDPN/ACVRL1	3
GO:0045932	negative regulation of muscle contraction	3/665	23/18722	0.0465993149461045	0.149877356992938	DOCK4/RGS2/KCNMA1	3
GO:0045980	negative regulation of nucleotide metabolic process	3/665	23/18722	0.0465993149461045	0.149877356992938	NUPR1/DDIT4/FBP1	3
GO:0051882	mitochondrial depolarization	3/665	23/18722	0.0465993149461045	0.149877356992938	IFI6/TSPO/LRRK2	3
GO:0060384	innervation	3/665	23/18722	0.0465993149461045	0.149877356992938	SULF2/GABRB2/NRP1	3
GO:0072576	liver morphogenesis	3/665	23/18722	0.0465993149461045	0.149877356992938	SULF2/CEBPB/TNFAIP3	3
GO:0006417	regulation of translation	24/665	468/18722	0.0466962990136625	0.149877356992938	VIM/ZFP36L2/EIF2AK2/PKM/YBX3/PPP1R15A/RPS27L/CNBP/ZFP36/ANG/GAPDH/EIF4EBP1/RHOA/RGS2/YBX1/PTAFR/NCL/PTK2B/EIF4E/TOB1/ZNF385A/ELAVL1/CPEB2/PER1	24
GO:0006869	lipid transport	21/665	398/18722	0.0469174537916844	0.149877356992938	PLIN2/TREM2/APOE/APOC1/NFKBIA/PLSCR1/APOL4/ACSL1/TSPO/CD36/IRS2/PIP4K2A/MSR1/ANXA1/OSBPL1A/SOAT1/ABCC3/ANXA2/APOL6/SCARB2/PSAP	21
GO:0001915	negative regulation of T cell mediated cytotoxicity	2/665	10/18722	0.046923373738634	0.149877356992938	FCGR2B/IL7R	2
GO:0002524	hypersensitivity	2/665	10/18722	0.046923373738634	0.149877356992938	FCGR2B/HLA-E	2
GO:0003056	regulation of vascular associated smooth muscle contraction	2/665	10/18722	0.046923373738634	0.149877356992938	DOCK4/RHOA	2
GO:0006222	UMP biosynthetic process	2/665	10/18722	0.046923373738634	0.149877356992938	UPP1/CMPK1	2
GO:0006735	NADH regeneration	2/665	10/18722	0.046923373738634	0.149877356992938	HK2/ENO1	2
GO:0009133	nucleoside diphosphate biosynthetic process	2/665	10/18722	0.046923373738634	0.149877356992938	CMPK1/GUK1	2
GO:0009174	pyrimidine ribonucleoside monophosphate biosynthetic process	2/665	10/18722	0.046923373738634	0.149877356992938	UPP1/CMPK1	2
GO:0009750	response to fructose	2/665	10/18722	0.046923373738634	0.149877356992938	SLC2A5/KRT18	2
GO:0010944	negative regulation of transcription by competitive promoter binding	2/665	10/18722	0.046923373738634	0.149877356992938	PHB/SMAD7	2
GO:0030388	fructose 1,6-bisphosphate metabolic process	2/665	10/18722	0.046923373738634	0.149877356992938	FBP1/ALDOA	2
GO:0032253	dense core granule localization	2/665	10/18722	0.046923373738634	0.149877356992938	TANC2/KIF5B	2
GO:0033089	positive regulation of T cell differentiation in thymus	2/665	10/18722	0.046923373738634	0.149877356992938	ADAM8/IL7R	2
GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway	2/665	10/18722	0.046923373738634	0.149877356992938	NAMPT/PARP9	2
GO:0034756	regulation of iron ion transport	2/665	10/18722	0.046923373738634	0.149877356992938	B2M/HAMP	2
GO:0042989	sequestering of actin monomers	2/665	10/18722	0.046923373738634	0.149877356992938	GSN/TMSB10	2
GO:0044557	relaxation of smooth muscle	2/665	10/18722	0.046923373738634	0.149877356992938	RGS2/KCNMA1	2
GO:0045625	regulation of T-helper 1 cell differentiation	2/665	10/18722	0.046923373738634	0.149877356992938	ANXA1/RIPK2	2
GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	2/665	10/18722	0.046923373738634	0.149877356992938	PLSCR1/RAP1A	2
GO:0060736	prostate gland growth	2/665	10/18722	0.046923373738634	0.149877356992938	PTEN/PSAP	2
GO:0061299	retina vasculature morphogenesis in camera-type eye	2/665	10/18722	0.046923373738634	0.149877356992938	CYP1B1/NRP1	2
GO:0061621	canonical glycolysis	2/665	10/18722	0.046923373738634	0.149877356992938	HK2/ENO1	2
GO:0061718	glucose catabolic process to pyruvate	2/665	10/18722	0.046923373738634	0.149877356992938	HK2/ENO1	2
GO:0071421	manganese ion transmembrane transport	2/665	10/18722	0.046923373738634	0.149877356992938	SLC11A1/ATP2C1	2
GO:0071803	positive regulation of podosome assembly	2/665	10/18722	0.046923373738634	0.149877356992938	MSN/RHOA	2
GO:0072203	cell proliferation involved in metanephros development	2/665	10/18722	0.046923373738634	0.149877356992938	STAT1/EGR1	2
GO:0072378	blood coagulation, fibrin clot formation	2/665	10/18722	0.046923373738634	0.149877356992938	F13A1/FN1	2
GO:0090647	modulation of age-related behavioral decline	2/665	10/18722	0.046923373738634	0.149877356992938	B2M/PRNP	2
GO:0097084	vascular associated smooth muscle cell development	2/665	10/18722	0.046923373738634	0.149877356992938	VEGFA/ADM	2
GO:0099519	dense core granule cytoskeletal transport	2/665	10/18722	0.046923373738634	0.149877356992938	TANC2/KIF5B	2
GO:0150172	regulation of phosphatidylcholine metabolic process	2/665	10/18722	0.046923373738634	0.149877356992938	CAPN2/APOC1	2
GO:1900246	positive regulation of RIG-I signaling pathway	2/665	10/18722	0.046923373738634	0.149877356992938	DDX60/OASL	2
GO:1901725	regulation of histone deacetylase activity	2/665	10/18722	0.046923373738634	0.149877356992938	VEGFA/LRRK2	2
GO:1901950	dense core granule transport	2/665	10/18722	0.046923373738634	0.149877356992938	TANC2/KIF5B	2
GO:1903980	positive regulation of microglial cell activation	2/665	10/18722	0.046923373738634	0.149877356992938	TREM2/LRRK2	2
GO:1904526	regulation of microtubule binding	2/665	10/18722	0.046923373738634	0.149877356992938	MAPRE1/PPP2CB	2
GO:1904896	ESCRT complex disassembly	2/665	10/18722	0.046923373738634	0.149877356992938	VTA1/CHMP5	2
GO:1904903	ESCRT III complex disassembly	2/665	10/18722	0.046923373738634	0.149877356992938	VTA1/CHMP5	2
GO:2001225	regulation of chloride transport	2/665	10/18722	0.046923373738634	0.149877356992938	PTAFR/PRNP	2
GO:0090398	cellular senescence	7/665	93/18722	0.0475326937481357	0.151212984582146	B2M/NAMPT/YBX1/MAP3K3/SPI1/CDKN1A/ABI3	7
GO:0097306	cellular response to alcohol	7/665	93/18722	0.0475326937481357	0.151212984582146	KLF4/SOD2/AHR/PTEN/KLF2/SPI1/KLF9	7
GO:1901796	regulation of signal transduction by p53 class mediator	7/665	93/18722	0.0475326937481357	0.151212984582146	CD74/SGK1/MIF/CD44/RRM2B/PLK3/ZNF385A	7
GO:0007040	lysosome organization	6/665	74/18722	0.047584931164281	0.151212984582146	RAB20/LRRK2/GRN/HEXB/SCARB2/CHMP5	6
GO:0010822	positive regulation of mitochondrion organization	6/665	74/18722	0.047584931164281	0.151212984582146	TREM2/BNIP3/PYCARD/FAM162A/RALA/PLAUR	6
GO:0048844	artery morphogenesis	6/665	74/18722	0.047584931164281	0.151212984582146	VEGFA/APOE/CITED2/ACVRL1/SMAD7/NRP1	6
GO:0051881	regulation of mitochondrial membrane potential	6/665	74/18722	0.047584931164281	0.151212984582146	IFI6/BNIP3L/TSPO/BNIP3/CLIC1/LRRK2	6
GO:0080171	lytic vacuole organization	6/665	74/18722	0.047584931164281	0.151212984582146	RAB20/LRRK2/GRN/HEXB/SCARB2/CHMP5	6
GO:0042445	hormone metabolic process	13/665	218/18722	0.0479991175468546	0.152431702369244	IL4I1/ADM/HSD17B4/TSPO/HSD17B11/CGA/EGR1/DHRS3/RBP1/CYP1B1/SLC16A10/TIPARP/HSD17B1	13
GO:0022900	electron transport chain	11/665	175/18722	0.048156810888474	0.152581671190927	NCF1/SDHD/SCO2/ALDH2/DNAJC15/DHRS3/PLEC/COA6/SDHB/CYCS/COX5B	11
GO:0050954	sensory perception of mechanical stimulus	11/665	175/18722	0.048156810888474	0.152581671190927	CXCR4/SLC1A3/KCNE1/GABRB2/TIMM8B/DIAPH1/HEXB/SCARB2/TIMM10/CXCL12/GPX1	11
GO:0098781	ncRNA transcription	5/665	56/18722	0.0481691432793892	0.152581671190927	ANG/NCL/LARP7/GTF3C6/SNAPC2	5
GO:1904645	response to amyloid-beta	5/665	56/18722	0.0481691432793892	0.152581671190927	FCGR2B/TREM2/CD36/NAMPT/PRNP	5
GO:2000785	regulation of autophagosome assembly	4/665	39/18722	0.0486462560836372	0.153994836137374	NUPR1/PIP4K2A/LRRK2/RNF5	4
GO:0001508	action potential	9/665	134/18722	0.0496321293272305	0.15701571149353	YWHAH/CALM1/GNAQ/CD36/FLNA/KCNE1/CALM3/KCNAB2/SCN9A	9
GO:0044772	mitotic cell cycle phase transition	22/665	424/18722	0.0496651453458171	0.157020211430478	GPNMB/DUSP1/ZFP36L2/CALM1/KLF4/PSME2/RPS27L/PTEN/CCNY/ANXA1/EIF4EBP1/EGFR/RPA2/CALM3/PLK3/CDKN1A/FBXL15/FOXN3/RB1/EIF4E/CCNI/XPC	22
GO:1901361	organic cyclic compound catabolic process	25/665	495/18722	0.0498569684242243	0.157526467303493	VIM/SLC11A1/OAS2/IL4I1/APOE/RNASE6/YWHAH/ZFP36L2/TYMP/YBX3/RNASET2/UPP1/SSB/ZFP36/ANG/HSD17B11/MYD88/HMOX1/YBX1/HNRNPA0/TOB1/KMO/HELZ2/ELAVL1/LSM6	25
GO:0010876	lipid localization	23/665	448/18722	0.0501790950428834	0.158443521196398	PLIN2/TREM2/APOE/APOC1/NFKBIA/PLSCR1/APOL4/ACSL1/TSPO/CD36/IRS2/PIP4K2A/MSR1/ANXA1/OSBPL1A/SOAT1/ABCC3/ANXA2/APOL6/HEXB/SCARB2/ABHD5/PSAP	23
GO:2001259	positive regulation of cation channel activity	6/665	75/18722	0.0502411170491617	0.158538636021799	TREM2/CALM1/IFNGR2/CALM3/KIF5B/EPHB2	6
GO:0022904	respiratory electron transport chain	8/665	114/18722	0.050298873296356	0.158620177844473	SDHD/SCO2/DNAJC15/PLEC/COA6/SDHB/CYCS/COX5B	8
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	19/665	355/18722	0.0505088416084593	0.159181320731796	VIM/JUN/DAB2/CSNK2B/SKIL/SMURF2/CITED2/PEG10/FOS/EGR1/FBN2/SDCBP/SPI1/ACVRL1/FBXL15/UBE2D1/TOB1/CDKN1C/SMAD7	19
GO:0033619	membrane protein proteolysis	5/665	57/18722	0.0513256193889037	0.16155055627793	APOE/CTSH/ADAM8/TIMP1/APH1A	5
GO:0097120	receptor localization to synapse	5/665	57/18722	0.0513256193889037	0.16155055627793	RAB8A/RAP1A/KIF5B/STX3/TYROBP	5
GO:0051302	regulation of cell division	11/665	177/18722	0.0514852072092127	0.161913190938432	VEGFA/TXNIP/EVI2B/CALM1/RHOA/YBX1/CALM3/PLK3/IGF2/PPBP/SETD2	11
GO:0001101	response to acid chemical	9/665	135/18722	0.0515859328970783	0.161913190938432	VEGFA/CD9/CAPN2/CEBPB/KLF2/RHOA/LAMTOR5/PLEC/RRAGD	9
GO:0001783	B cell apoptotic process	3/665	24/18722	0.0518969241780526	0.161913190938432	CD74/IRS2/PTEN	3
GO:0002922	positive regulation of humoral immune response	3/665	24/18722	0.0518969241780526	0.161913190938432	FCGR2B/TREM2/PHB	3
GO:0031639	plasminogen activation	3/665	24/18722	0.0518969241780526	0.161913190938432	PGK1/ENO1/PLAU	3
GO:0036010	protein localization to endosome	3/665	24/18722	0.0518969241780526	0.161913190938432	MSN/DTX3L/NRP1	3
GO:0043302	positive regulation of leukocyte degranulation	3/665	24/18722	0.0518969241780526	0.161913190938432	HLA-F/ITGAM/PTAFR	3
GO:0050855	regulation of B cell receptor signaling pathway	3/665	24/18722	0.0518969241780526	0.161913190938432	FCGR2B/CD300A/CD81	3
GO:0051043	regulation of membrane protein ectodomain proteolysis	3/665	24/18722	0.0518969241780526	0.161913190938432	APOE/ADAM8/TIMP1	3
GO:0051156	glucose 6-phosphate metabolic process	3/665	24/18722	0.0518969241780526	0.161913190938432	HK2/GPI/PGAM1	3
GO:0090343	positive regulation of cell aging	3/665	24/18722	0.0518969241780526	0.161913190938432	B2M/LMNA/ABI3	3
GO:0120255	olefinic compound biosynthetic process	3/665	24/18722	0.0518969241780526	0.161913190938432	ADM/EGR1/HSD17B1	3
GO:2000310	regulation of NMDA receptor activity	3/665	24/18722	0.0518969241780526	0.161913190938432	IFNGR2/PTK2B/EPHB2	3
GO:2000679	positive regulation of transcription regulatory region DNA binding	3/665	24/18722	0.0518969241780526	0.161913190938432	KLF4/LAMTOR5/RB1	3
GO:0008585	female gonad development	7/665	95/18722	0.0522552707176657	0.162826768317742	NUPR1/VEGFA/CEBPB/ANG/IDH1/MMP14/TIPARP	7
GO:1901379	regulation of potassium ion transmembrane transport	7/665	95/18722	0.0522552707176657	0.162826768317742	TREM2/PTEN/FLNA/KCNE1/WNK1/KCNAB2/PRNP	7
GO:0016358	dendrite development	14/665	243/18722	0.0522904906933662	0.162834422773202	APOE/YWHAH/TANC2/ABI1/PTEN/RHOA/LRRK2/UBA6/CAMK1/ABI3/EPHB2/CFL1/SIPA1L1/NRP1	14
GO:0008406	gonad development	13/665	221/18722	0.0524527355699611	0.163160130836602	NUPR1/VEGFA/CEBPB/YBX3/HSD17B4/ANG/IDH1/CGA/CITED2/FLNA/MMP14/RAB13/TIPARP	13
GO:0030278	regulation of ossification	8/665	115/18722	0.0524607422689918	0.163160130836602	ISG15/SRGN/ALOX5/ECM1/DHRS3/FBN2/PTK2B/SMAD7	8
GO:0034122	negative regulation of toll-like receptor signaling pathway	4/665	40/18722	0.0525940634914593	0.16316635178062	TREM2/CD300A/TNFAIP3/GRAMD4	4
GO:0045740	positive regulation of DNA replication	4/665	40/18722	0.0525940634914593	0.16316635178062	JUN/RAC1/EGFR/CACYBP	4
GO:0150077	regulation of neuroinflammatory response	4/665	40/18722	0.0525940634914593	0.16316635178062	NUPR1/TREM2/LRRK2/GRN	4
GO:1901020	negative regulation of calcium ion transmembrane transporter activity	4/665	40/18722	0.0525940634914593	0.16316635178062	CALM1/CLIC2/CALM3/C4orf3	4
GO:0009266	response to temperature stimulus	11/665	178/18722	0.0532060789434091	0.164962078820177	CXCR4/NFKBIA/ERO1A/ADM/SOD2/HMOX1/IER5/FOS/SLU7/CDKN1A/CXCL12	11
GO:0018208	peptidyl-proline modification	5/665	58/18722	0.0546002824744417	0.168823202864374	EGLN3/P4HA1/ERO1A/FKBP5/EGLN1	5
GO:0032387	negative regulation of intracellular transport	5/665	58/18722	0.0546002824744417	0.168823202864374	CD36/KCNE1/LRRK2/TXN/MDFIC	5
GO:0042743	hydrogen peroxide metabolic process	5/665	58/18722	0.0546002824744417	0.168823202864374	SOD2/HBG1/RAC1/EGFR/GPX1	5
GO:2000649	regulation of sodium ion transmembrane transporter activity	5/665	58/18722	0.0546002824744417	0.168823202864374	YWHAH/FXYD5/GLRX/WNK1/KIF5B	5
GO:0018107	peptidyl-threonine phosphorylation	8/665	116/18722	0.054681450737312	0.168823202864374	DDIT4/CALM1/CSNK2B/LRRK2/WNK1/CALM3/SMAD7/RIPK2	8
GO:0033559	unsaturated fatty acid metabolic process	8/665	116/18722	0.054681450737312	0.168823202864374	CD74/ALOX5/SCD/MIF/ANXA1/PTGES3/CYP1B1/GPX1	8
GO:0030510	regulation of BMP signaling pathway	7/665	96/18722	0.0547231750129793	0.168823202864374	SKIL/SMURF2/ACVRL1/FBXL15/UBE2D1/TOB1/SMAD7	7
GO:0044264	cellular polysaccharide metabolic process	7/665	96/18722	0.0547231750129793	0.168823202864374	IRS2/PPP1CB/PPP1R3B/B3GNT7/PTGES3/PHLDA2/IGF2	7
GO:0006941	striated muscle contraction	11/665	179/18722	0.0549650801759376	0.16899753717846	CXCR4/CALM1/ALDOA/GSN/CLIC2/FLNA/KCNE1/RGS2/CALM3/NR4A1/SMAD7	11
GO:0007626	locomotory behavior	11/665	179/18722	0.0549650801759376	0.16899753717846	APOE/NR4A2/CSTB/PTEN/EGR1/ARRDC3/LRRK2/UBA6/HEXB/CXCL12/VPS13A	11
GO:1901991	negative regulation of mitotic cell cycle phase transition	11/665	179/18722	0.0549650801759376	0.16899753717846	GPNMB/DUSP1/ZFP36L2/KLF4/RPS27L/PTEN/RPA2/PLK3/CDKN1A/FOXN3/RB1	11
GO:0071375	cellular response to peptide hormone stimulus	16/665	290/18722	0.0551671332150061	0.16899753717846	STAT1/PKM/NR4A2/ERRFI1/RAB8A/IRS2/PIP4K2A/GRB2/PTEN/SOCS3/INSIG2/RAB13/IGF2/NR4A1/RAB31/CPEB2	16
GO:0051052	regulation of DNA metabolic process	19/665	359/18722	0.0552730516634554	0.16899753717846	DUSP1/KLF4/TERF2IP/UBE2B/DTX3L/PARP9/PTGES3/EGFR/RPA2/IL7R/IL27RA/SPI1/CDKN1A/ACVRL1/HNRNPA1/PTK2B/KDM1B/TFRC/SETD2	19
GO:0043488	regulation of mRNA stability	10/665	158/18722	0.0556314622174239	0.16899753717846	VIM/SLC11A1/ZFP36L2/YBX3/ZFP36/MYD88/YBX1/HNRNPA0/TOB1/ELAVL1	10
GO:0060048	cardiac muscle contraction	9/665	137/18722	0.0556431747514581	0.16899753717846	CXCR4/CALM1/GSN/CLIC2/FLNA/KCNE1/RGS2/CALM3/SMAD7	9
GO:0001765	membrane raft assembly	2/665	11/18722	0.0560295394329613	0.16899753717846	S100A10/ANXA2	2
GO:0002327	immature B cell differentiation	2/665	11/18722	0.0560295394329613	0.16899753717846	IRF2BP2/SPI1	2
GO:0002725	negative regulation of T cell cytokine production	2/665	11/18722	0.0560295394329613	0.16899753717846	HLA-F/SMAD7	2
GO:0006002	fructose 6-phosphate metabolic process	2/665	11/18722	0.0560295394329613	0.16899753717846	HK2/FBP1	2
GO:0006568	tryptophan metabolic process	2/665	11/18722	0.0560295394329613	0.16899753717846	IL4I1/KMO	2
GO:0010269	response to selenium ion	2/665	11/18722	0.0560295394329613	0.16899753717846	SOD2/GPX1	2
GO:0010986	positive regulation of lipoprotein particle clearance	2/665	11/18722	0.0560295394329613	0.16899753717846	TREM2/ANXA2	2
GO:0032493	response to bacterial lipoprotein	2/665	11/18722	0.0560295394329613	0.16899753717846	CD36/TLR2	2
GO:0032957	inositol trisphosphate metabolic process	2/665	11/18722	0.0560295394329613	0.16899753717846	PTAFR/PTK2B	2
GO:0033483	gas homeostasis	2/665	11/18722	0.0560295394329613	0.16899753717846	SOD2/EGLN1	2
GO:0034163	regulation of toll-like receptor 9 signaling pathway	2/665	11/18722	0.0560295394329613	0.16899753717846	RSAD2/GRAMD4	2
GO:0034379	very-low-density lipoprotein particle assembly	2/665	11/18722	0.0560295394329613	0.16899753717846	APOC1/SOAT1	2
GO:0034776	response to histamine	2/665	11/18722	0.0560295394329613	0.16899753717846	GABRB2/DIAPH1	2
GO:0035457	cellular response to interferon-alpha	2/665	11/18722	0.0560295394329613	0.16899753717846	IFIT3/IFIT2	2
GO:0042789	mRNA transcription by RNA polymerase II	2/665	11/18722	0.0560295394329613	0.16899753717846	C5AR1/FLNA	2
GO:0048102	autophagic cell death	2/665	11/18722	0.0560295394329613	0.16899753717846	TREM2/BNIP3	2
GO:0048680	positive regulation of axon regeneration	2/665	11/18722	0.0560295394329613	0.16899753717846	FLNA/GRN	2
GO:0051574	positive regulation of histone H3-K9 methylation	2/665	11/18722	0.0560295394329613	0.16899753717846	LMNA/JARID2	2
GO:0070944	neutrophil-mediated killing of bacterium	2/665	11/18722	0.0560295394329613	0.16899753717846	MYD88/TREM1	2
GO:0075733	intracellular transport of virus	2/665	11/18722	0.0560295394329613	0.16899753717846	BST2/KPNA3	2
GO:0090394	negative regulation of excitatory postsynaptic potential	2/665	11/18722	0.0560295394329613	0.16899753717846	PTEN/LRRK2	2
GO:0090649	response to oxygen-glucose deprivation	2/665	11/18722	0.0560295394329613	0.16899753717846	NAMPT/BNIP3	2
GO:0098792	xenophagy	2/665	11/18722	0.0560295394329613	0.16899753717846	WIPI2/RIPK2	2
GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	2/665	11/18722	0.0560295394329613	0.16899753717846	CD36/MYD88	2
GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction	2/665	11/18722	0.0560295394329613	0.16899753717846	CALM1/CALM3	2
GO:1902667	regulation of axon guidance	2/665	11/18722	0.0560295394329613	0.16899753717846	VEGFA/NRP1	2
GO:1905668	positive regulation of protein localization to endosome	2/665	11/18722	0.0560295394329613	0.16899753717846	MSN/DTX3L	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	2/665	11/18722	0.0560295394329613	0.16899753717846	CEBPB/ATF3	2
GO:2000392	regulation of lamellipodium morphogenesis	2/665	11/18722	0.0560295394329613	0.16899753717846	CD44/PDPN	2
GO:0001894	tissue homeostasis	15/665	268/18722	0.056071818673497	0.16899753717846	VEGFA/B2M/LYZ/CTSH/ADAM8/OAS1/ACP5/SNX10/HAMP/TNFAIP3/RAC1/EGFR/PTK2B/TFRC/RB1	15
GO:0050708	regulation of protein secretion	15/665	268/18722	0.056071818673497	0.16899753717846	HLA-DRB1/TREM2/APOE/ADAM8/ALOX5/RSAD2/GLUL/DYNLL1/IRS2/ANG/RAC1/ANXA1/EGFR/KIF5B/TLR2	15
GO:0050892	intestinal absorption	4/665	41/18722	0.0567109580479401	0.170820279695917	SLC2A5/CD36/HAMP/EPB41	4
GO:0015698	inorganic anion transport	11/665	180/18722	0.0567624545103148	0.170871834594951	SLC11A1/SLC1A3/CEBPB/TSPO/CLIC2/CLIC1/GABRB2/PTAFR/ABCC3/TTYH3/PRNP	11
GO:0019722	calcium-mediated signaling	12/665	202/18722	0.0572216163513925	0.171960830208603	CXCR4/TREM2/CALM1/CXCL8/CLEC7A/CLIC2/GBP1/EGFR/LRRK2/CALM3/PTK2B/PRNP	12
GO:0032388	positive regulation of intracellular transport	12/665	202/18722	0.0572216163513925	0.171960830208603	DAB2/MSN/ITGAM/FLNA/HCLS1/PLK3/KIF5B/CAMK1/ANXA2/OAZ1/CD81/PRNP	12
GO:0043255	regulation of carbohydrate biosynthetic process	7/665	97/18722	0.0572626104618184	0.171960830208603	FBP1/IRS2/PPP1CB/PPP1R3B/PTAFR/PTK2B/IGF2	7
GO:0070167	regulation of biomineral tissue development	7/665	97/18722	0.0572626104618184	0.171960830208603	ISG15/SRGN/ALOX5/CEBPB/ECM1/FBN2/PTK2B	7
GO:0032878	regulation of establishment or maintenance of cell polarity	3/665	25/18722	0.0574715221481272	0.171964759227088	GSN/PTK2B/DOCK8	3
GO:0042730	fibrinolysis	3/665	25/18722	0.0574715221481272	0.171964759227088	SERPING1/PLAU/ANXA2	3
GO:0050927	positive regulation of positive chemotaxis	3/665	25/18722	0.0574715221481272	0.171964759227088	VEGFA/CXCL8/CXCL12	3
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	3/665	25/18722	0.0574715221481272	0.171964759227088	NFKBIA/TNFAIP3/RIPK2	3
GO:1903959	regulation of anion transmembrane transport	3/665	25/18722	0.0574715221481272	0.171964759227088	RGS2/PTAFR/PRNP	3
GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	3/665	25/18722	0.0574715221481272	0.171964759227088	ALOX5/RHOA/PTAFR	3
GO:1903322	positive regulation of protein modification by small protein conjugation or removal	9/665	138/18722	0.0577472138798738	0.172685711782776	NMI/PTEN/ARRDC3/RBX1/LRRK2/TANK/UBE2D1/SMAD7/RIPK2	9
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	5/665	59/18722	0.0579931361987212	0.173108640785372	CD300A/SH3BP5/ERRFI1/SOCS3/SAMSN1	5
GO:0051353	positive regulation of oxidoreductase activity	5/665	59/18722	0.0579931361987212	0.173108640785372	APOE/CALM1/CALM3/PTK2B/PIK3CB	5
GO:2001258	negative regulation of cation channel activity	5/665	59/18722	0.0579931361987212	0.173108640785372	CALM1/CLIC2/KCNE1/CALM3/EPHB2	5
GO:0045786	negative regulation of cell cycle	20/665	385/18722	0.0585829737208003	0.174621132490289	ATF5/NUPR1/GPNMB/DUSP1/ZFP36L2/BTG1/KLF4/RPS27L/TNFAIP3/PTEN/RHOB/EGFR/RPA2/PLK3/CDKN1A/FOXN3/RB1/NR4A1/CDKN1C/XPC	20
GO:0097696	receptor signaling pathway via STAT	11/665	181/18722	0.0585984319024362	0.174621132490289	CD300A/STAT1/NMI/HAMP/SOCS3/PARP9/HCLS1/IL7R/PTK2B/ARL2BP/CYP1B1	11
GO:0019319	hexose biosynthetic process	6/665	78/18722	0.0587457813931114	0.174621132490289	PGK1/FBP1/ATF3/TPI1/GPI/CHST15	6
GO:0030500	regulation of bone mineralization	6/665	78/18722	0.0587457813931114	0.174621132490289	ISG15/SRGN/ALOX5/ECM1/FBN2/PTK2B	6
GO:0032024	positive regulation of insulin secretion	6/665	78/18722	0.0587457813931114	0.174621132490289	HLA-DRB1/GLUL/DYNLL1/IRS2/RAC1/KIF5B	6
GO:0032371	regulation of sterol transport	6/665	78/18722	0.0587457813931114	0.174621132490289	TREM2/APOE/APOC1/NFKBIA/TSPO/ANXA2	6
GO:0032374	regulation of cholesterol transport	6/665	78/18722	0.0587457813931114	0.174621132490289	TREM2/APOE/APOC1/NFKBIA/TSPO/ANXA2	6
GO:0000266	mitochondrial fission	4/665	42/18722	0.0609956999841871	0.180876270239505	INF2/BNIP3/RALA/LRRK2	4
GO:0010939	regulation of necrotic cell death	4/665	42/18722	0.0609956999841871	0.180876270239505	NUPR1/YBX3/TSPO/BNIP3	4
GO:0045773	positive regulation of axon extension	4/665	42/18722	0.0609956999841871	0.180876270239505	VEGFA/FN1/CXCL12/NRP1	4
GO:0048489	synaptic vesicle transport	4/665	42/18722	0.0609956999841871	0.180876270239505	BLOC1S1/BLOC1S2/LRRK2/KIF5B	4
GO:0002712	regulation of B cell mediated immunity	5/665	60/18722	0.0615040315437102	0.181841187847852	FCGR2B/TREM2/IL27RA/HLA-E/TFRC	5
GO:0002889	regulation of immunoglobulin mediated immune response	5/665	60/18722	0.0615040315437102	0.181841187847852	FCGR2B/TREM2/IL27RA/HLA-E/TFRC	5
GO:0006893	Golgi to plasma membrane transport	5/665	60/18722	0.0615040315437102	0.181841187847852	VAMP5/GOLGA7/KRT18/RAB31/ATP2C1	5
GO:0019731	antibacterial humoral response	5/665	60/18722	0.0615040315437102	0.181841187847852	HLA-A/RNASE6/ANG/HLA-E/RPL39	5
GO:0042306	regulation of protein import into nucleus	5/665	60/18722	0.0615040315437102	0.181841187847852	CD36/NUP58/FLNA/HCLS1/MDFIC	5
GO:0031398	positive regulation of protein ubiquitination	8/665	119/18722	0.0616996658640044	0.182164974452049	NMI/PTEN/ARRDC3/RBX1/LRRK2/UBE2D1/SMAD7/RIPK2	8
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	6/665	79/18722	0.0617601573343465	0.182164974452049	LIMS1/S100A10/MYADM/RAC1/FLNA/NRP1	6
GO:0060420	regulation of heart growth	6/665	79/18722	0.0617601573343465	0.182164974452049	HAMP/CITED2/PTEN/RGS2/JARID2/DUSP6	6
GO:1901184	regulation of ERBB signaling pathway	6/665	79/18722	0.0617601573343465	0.182164974452049	IFI6/ERRFI1/NCF1/PTPN12/EGFR/PLAUR	6
GO:0030177	positive regulation of Wnt signaling pathway	9/665	140/18722	0.0621074439168138	0.18297213768024	SULF2/DAB2/UBE2B/TNFAIP3/SMURF2/EGFR/LRRK2/WNK1/TLR2	9
GO:0031333	negative regulation of protein-containing complex assembly	9/665	140/18722	0.0621074439168138	0.18297213768024	TREM2/CAPG/MYADM/GSN/MAPRE1/DNAJC15/EIF4EBP1/AIDA/TMSB10	9
GO:0046777	protein autophosphorylation	13/665	227/18722	0.0621892935473815	0.183104732778724	VEGFA/GPNMB/EIF2AK2/CALM1/ERRFI1/RASSF2/PRKX/EGFR/LRRK2/WNK1/CALM3/MAP3K3/PTK2B	13
GO:0110149	regulation of biomineralization	7/665	99/18722	0.0625571150713988	0.184078663057935	ISG15/SRGN/ALOX5/CEBPB/ECM1/FBN2/PTK2B	7
GO:0002407	dendritic cell chemotaxis	3/665	26/18722	0.0633163260337944	0.184781057186118	CXCR4/GPR183/SPI1	3
GO:0006027	glycosaminoglycan catabolic process	3/665	26/18722	0.0633163260337944	0.184781057186118	CD44/IDS/LYVE1	3
GO:0006706	steroid catabolic process	3/665	26/18722	0.0633163260337944	0.184781057186118	APOE/YWHAH/HSD17B11	3
GO:0008535	respiratory chain complex IV assembly	3/665	26/18722	0.0633163260337944	0.184781057186118	SCO2/COA6/COX16	3
GO:0009435	NAD biosynthetic process	3/665	26/18722	0.0633163260337944	0.184781057186118	NAMPT/PARP9/KMO	3
GO:0010875	positive regulation of cholesterol efflux	3/665	26/18722	0.0633163260337944	0.184781057186118	TREM2/APOE/NFKBIA	3
GO:0032682	negative regulation of chemokine production	3/665	26/18722	0.0633163260337944	0.184781057186118	OAS1/OAS3/KLF4	3
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	3/665	26/18722	0.0633163260337944	0.184781057186118	NFKBIA/TNFAIP3/RIPK2	3
GO:0050926	regulation of positive chemotaxis	3/665	26/18722	0.0633163260337944	0.184781057186118	VEGFA/CXCL8/CXCL12	3
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	3/665	26/18722	0.0633163260337944	0.184781057186118	CALM1/CLIC2/CALM3	3
GO:0097066	response to thyroid hormone	3/665	26/18722	0.0633163260337944	0.184781057186118	CTSH/KLF9/ANXA2	3
GO:1904861	excitatory synapse assembly	3/665	26/18722	0.0633163260337944	0.184781057186118	IL1RAP/PTEN/ABI3	3
GO:1905523	positive regulation of macrophage migration	3/665	26/18722	0.0633163260337944	0.184781057186118	TREM2/C5AR1/MMP14	3
GO:2000108	positive regulation of leukocyte apoptotic process	3/665	26/18722	0.0633163260337944	0.184781057186118	ADAM8/ANXA1/PIK3CB	3
GO:0034249	negative regulation of cellular amide metabolic process	15/665	273/18722	0.06365584094282	0.185662869416558	APOE/ZFP36L2/EIF2AK2/ZFP36/ANG/GAPDH/EIF4EBP1/RGS2/YBX1/NCL/RTN3/EIF4E/TOB1/CPEB2/PRNP	15
GO:0071774	response to fibroblast growth factor	8/665	120/18722	0.0641586063668472	0.187019515333273	SULF2/ZFP36L2/CXCL8/CD44/ZFP36/SHOC2/NR4A1/IER2	8
GO:0009791	post-embryonic development	6/665	80/18722	0.0648644544455342	0.187312798846457	ATF5/VEGFA/KLF4/NR4A2/SCN9A/TIPARP	6
GO:0034113	heterotypic cell-cell adhesion	5/665	61/18722	0.0651326698385162	0.187312798846457	KLF4/MYADM/CD44/WNK1/CD58	5
GO:0006626	protein targeting to mitochondrion	7/665	100/18722	0.0653125699970137	0.187312798846457	BNIP3L/TSPO/DNAJC15/LRRK2/TIMM8B/HAX1/TIMM10	7
GO:0019218	regulation of steroid metabolic process	7/665	100/18722	0.0653125699970137	0.187312798846457	APOE/APOC1/ADM/TSPO/CGA/EGR1/INSIG2	7
GO:0006509	membrane protein ectodomain proteolysis	4/665	43/18722	0.0654467570970569	0.187312798846457	APOE/ADAM8/TIMP1/APH1A	4
GO:0042181	ketone biosynthetic process	4/665	43/18722	0.0654467570970569	0.187312798846457	ADM/TPI1/EGR1/HSD17B1	4
GO:0046636	negative regulation of alpha-beta T cell activation	4/665	43/18722	0.0654467570970569	0.187312798846457	CD300A/TNFRSF14/ANXA1/SMAD7	4
GO:1901381	positive regulation of potassium ion transmembrane transport	4/665	43/18722	0.0654467570970569	0.187312798846457	TREM2/FLNA/KCNE1/WNK1	4
GO:0002674	negative regulation of acute inflammatory response	2/665	12/18722	0.065691390017983	0.187312798846457	FCGR2B/NLRP3	2
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	2/665	12/18722	0.065691390017983	0.187312798846457	HLA-E/CD81	2
GO:0002903	negative regulation of B cell apoptotic process	2/665	12/18722	0.065691390017983	0.187312798846457	CD74/IRS2	2
GO:0006703	estrogen biosynthetic process	2/665	12/18722	0.065691390017983	0.187312798846457	HSD17B11/HSD17B1	2
GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process	2/665	12/18722	0.065691390017983	0.187312798846457	TYMP/UPP1	2
GO:0014831	gastro-intestinal system smooth muscle contraction	2/665	12/18722	0.065691390017983	0.187312798846457	SULF2/PTAFR	2
GO:0014889	muscle atrophy	2/665	12/18722	0.065691390017983	0.187312798846457	GSN/GATM	2
GO:0032490	detection of molecule of bacterial origin	2/665	12/18722	0.065691390017983	0.187312798846457	TREM2/TLR2	2
GO:0032736	positive regulation of interleukin-13 production	2/665	12/18722	0.065691390017983	0.187312798846457	IL1RAP/HLA-E	2
GO:0033004	negative regulation of mast cell activation	2/665	12/18722	0.065691390017983	0.187312798846457	CD300A/HMOX1	2
GO:0033629	negative regulation of cell adhesion mediated by integrin	2/665	12/18722	0.065691390017983	0.187312798846457	WNK1/CYP1B1	2
GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	2/665	12/18722	0.065691390017983	0.187312798846457	IFI35/WDFY1	2
GO:0038180	nerve growth factor signaling pathway	2/665	12/18722	0.065691390017983	0.187312798846457	RAP1A/RAPGEF1	2
GO:0045039	protein insertion into mitochondrial inner membrane	2/665	12/18722	0.065691390017983	0.187312798846457	TIMM8B/TIMM10	2
GO:0045602	negative regulation of endothelial cell differentiation	2/665	12/18722	0.065691390017983	0.187312798846457	VEGFA/ACVRL1	2
GO:0046185	aldehyde catabolic process	2/665	12/18722	0.065691390017983	0.187312798846457	ESD/HAGH	2
GO:0060907	positive regulation of macrophage cytokine production	2/665	12/18722	0.065691390017983	0.187312798846457	CD74/CD36	2
GO:0070213	protein auto-ADP-ribosylation	2/665	12/18722	0.065691390017983	0.187312798846457	PARP12/TIPARP	2
GO:0070572	positive regulation of neuron projection regeneration	2/665	12/18722	0.065691390017983	0.187312798846457	FLNA/GRN	2
GO:0070943	neutrophil-mediated killing of symbiont cell	2/665	12/18722	0.065691390017983	0.187312798846457	MYD88/TREM1	2
GO:0071635	negative regulation of transforming growth factor beta production	2/665	12/18722	0.065691390017983	0.187312798846457	TYROBP/FN1	2
GO:0072376	protein activation cascade	2/665	12/18722	0.065691390017983	0.187312798846457	F13A1/FN1	2
GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress	2/665	12/18722	0.065691390017983	0.187312798846457	JUN/CITED2	2
GO:0099151	regulation of postsynaptic density assembly	2/665	12/18722	0.065691390017983	0.187312798846457	IL1RAP/ABI3	2
GO:0150065	regulation of deacetylase activity	2/665	12/18722	0.065691390017983	0.187312798846457	VEGFA/LRRK2	2
GO:1903909	regulation of receptor clustering	2/665	12/18722	0.065691390017983	0.187312798846457	GSN/CD81	2
GO:1905666	regulation of protein localization to endosome	2/665	12/18722	0.065691390017983	0.187312798846457	MSN/DTX3L	2
GO:1905709	negative regulation of membrane permeability	2/665	12/18722	0.065691390017983	0.187312798846457	HK2/BNIP3	2
GO:1990034	calcium ion export across plasma membrane	2/665	12/18722	0.065691390017983	0.187312798846457	CALM1/CALM3	2
GO:2000317	negative regulation of T-helper 17 type immune response	2/665	12/18722	0.065691390017983	0.187312798846457	IL27RA/SMAD7	2
GO:0061025	membrane fusion	10/665	163/18722	0.0657891062387558	0.187483863535904	CD9/SAMD9/RAB8A/PIP4K2A/RAB20/ANXA1/KIF5B/STX3/RAB13/ANXA2	10
GO:0051896	regulation of protein kinase B signaling	11/665	185/18722	0.0663324824107135	0.188924032997849	ADAM8/KLF4/PTEN/HCLS1/EGFR/TXN/IGF2/PIK3CB/PHB/HAX1/GPX1	11
GO:1904019	epithelial cell apoptotic process	8/665	121/18722	0.0666776439424155	0.18979833355888	NUPR1/ZFP36/GSN/TNFAIP3/HMOX1/KRT18/RB1/ANGPTL4	8
GO:0071692	protein localization to extracellular region	19/665	368/18722	0.0671267072896401	0.190967221081575	HLA-DRB1/TREM2/APOE/ADAM8/ALOX5/RSAD2/GLUL/DYNLL1/RAB8A/IRS2/ANG/RAC1/ANXA1/EGFR/FBN2/KIF5B/TMEM167A/RAB13/TLR2	19
GO:0045333	cellular respiration	13/665	230/18722	0.0674821231930582	0.191868508163329	NUPR1/SDHD/SCO2/IDH1/BNIP3/BLOC1S1/DNAJC15/RHOA/PLEC/COA6/SDHB/CYCS/COX5B	13
GO:0050680	negative regulation of epithelial cell proliferation	10/665	164/18722	0.0679540187684427	0.193065922241157	NUPR1/B2M/APOE/STAT1/ALOX5/PTEN/ACVRL1/KLF9/RB1/CDKN1C	10
GO:0044773	mitotic DNA damage checkpoint signaling	6/665	81/18722	0.0680586510596593	0.193065922241157	RPS27L/RPA2/PLK3/CDKN1A/FOXN3/XPC	6
GO:1903533	regulation of protein targeting	6/665	81/18722	0.0680586510596593	0.193065922241157	BNIP3L/ITGAM/KCNE1/LRRK2/HAX1/PRNP	6
GO:2000243	positive regulation of reproductive process	6/665	81/18722	0.0680586510596593	0.193065922241157	LHFPL2/VEGFA/UBE2B/SMURF2/CITED2/PTAFR	6
GO:0008217	regulation of blood pressure	11/665	186/18722	0.0683644331513339	0.193822722625288	SLC2A5/SGK1/ADM/SOD2/NAMPT/ANPEP/HMOX1/RHOA/PTAFR/WNK1/ACVRL1	11
GO:0007548	sex differentiation	15/665	276/18722	0.06852370688727	0.194163525216495	NUPR1/LHFPL2/VEGFA/CEBPB/YBX3/MERTK/HSD17B4/ANG/IDH1/CGA/CITED2/FLNA/MMP14/RAB13/TIPARP	15
GO:0019933	cAMP-mediated signaling	5/665	62/18722	0.0688786060528303	0.19483589759964	ADM/AHR/UBE2B/RGS2/CAP1	5
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	5/665	62/18722	0.0688786060528303	0.19483589759964	DAB2/CSNK2B/SDCBP/ACVRL1/SMAD7	5
GO:0070265	necrotic cell death	5/665	62/18722	0.0688786060528303	0.19483589759964	NUPR1/YBX3/TSPO/BNIP3/TMEM123	5
GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	3/665	27/18722	0.0694239939510119	0.195488526876221	FCGR2B/MYO1G/RAP1A	3
GO:0010758	regulation of macrophage chemotaxis	3/665	27/18722	0.0694239939510119	0.195488526876221	C5AR1/MIF/PTK2B	3
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	3/665	27/18722	0.0694239939510119	0.195488526876221	CALM1/CLIC2/CALM3	3
GO:0034377	plasma lipoprotein particle assembly	3/665	27/18722	0.0694239939510119	0.195488526876221	APOE/APOC1/SOAT1	3
GO:0036037	CD8-positive, alpha-beta T cell activation	3/665	27/18722	0.0694239939510119	0.195488526876221	HLA-A/CLEC4A/HLA-E	3
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	3/665	27/18722	0.0694239939510119	0.195488526876221	FCGR2B/MYO1G/RAP1A	3
GO:0042104	positive regulation of activated T cell proliferation	3/665	27/18722	0.0694239939510119	0.195488526876221	PYCARD/IL27RA/IGF2	3
GO:1903421	regulation of synaptic vesicle recycling	3/665	27/18722	0.0694239939510119	0.195488526876221	CALM1/LRRK2/CALM3	3
GO:0009262	deoxyribonucleotide metabolic process	4/665	44/18722	0.0700623191233519	0.196617575405454	TYMP/UPP1/RRM2B/GUK1	4
GO:0032620	interleukin-17 production	4/665	44/18722	0.0700623191233519	0.196617575405454	MYD88/IL27RA/PHB/PRNP	4
GO:0032660	regulation of interleukin-17 production	4/665	44/18722	0.0700623191233519	0.196617575405454	MYD88/IL27RA/PHB/PRNP	4
GO:0046006	regulation of activated T cell proliferation	4/665	44/18722	0.0700623191233519	0.196617575405454	PYCARD/IL27RA/IGF2/PRNP	4
GO:0150076	neuroinflammatory response	4/665	44/18722	0.0700623191233519	0.196617575405454	NUPR1/TREM2/LRRK2/GRN	4
GO:1903573	negative regulation of response to endoplasmic reticulum stress	4/665	44/18722	0.0700623191233519	0.196617575405454	ALOX5/PPP1R15A/LRRK2/GRINA	4
GO:0006402	mRNA catabolic process	13/665	232/18722	0.0711707122251979	0.199534567972396	VIM/SLC11A1/ZFP36L2/YBX3/SSB/ZFP36/MYD88/YBX1/HNRNPA0/TOB1/HELZ2/ELAVL1/LSM6	13
GO:0046364	monosaccharide biosynthetic process	6/665	82/18722	0.071342641305221	0.199534567972396	PGK1/FBP1/ATF3/TPI1/GPI/CHST15	6
GO:0046889	positive regulation of lipid biosynthetic process	6/665	82/18722	0.071342641305221	0.199534567972396	APOE/CAPN2/CD74/ADM/CGA/ANXA1	6
GO:0060395	SMAD protein signal transduction	6/665	82/18722	0.071342641305221	0.199534567972396	VIM/JUN/DAB2/FOS/TOB1/SMAD7	6
GO:0072527	pyrimidine-containing compound metabolic process	6/665	82/18722	0.071342641305221	0.199534567972396	NT5C3A/TYMP/UPP1/CMPK1/SLC25A19/ERH	6
GO:1905897	regulation of response to endoplasmic reticulum stress	6/665	82/18722	0.071342641305221	0.199534567972396	FCGR2B/NUPR1/ALOX5/PPP1R15A/LRRK2/GRINA	6
GO:0014065	phosphatidylinositol 3-kinase signaling	9/665	144/18722	0.0714422781269122	0.199700856181526	TREM2/KLF4/NCF1/PTEN/HCLS1/EGFR/PIK3CB/FN1/HAX1	9
GO:0061013	regulation of mRNA catabolic process	10/665	166/18722	0.0724185488968809	0.202316013500561	VIM/SLC11A1/ZFP36L2/YBX3/ZFP36/MYD88/YBX1/HNRNPA0/TOB1/ELAVL1	10
GO:0006575	cellular modified amino acid metabolic process	11/665	188/18722	0.0725475208225586	0.202448724586253	SLC6A8/PLSCR1/CLIC2/IDH1/CGA/CLIC1/SERINC1/GATM/SLC16A10/HAGH/GPX1	11
GO:0030308	negative regulation of cell growth	11/665	188/18722	0.0725475208225586	0.202448724586253	BTG1/FBP1/BST2/ENO1/RGS2/CDKN1A/ACVRL1/RB1/CCDC85B/PHB/NRP1	11
GO:0016239	positive regulation of macroautophagy	5/665	63/18722	0.072741252332143	0.202647995566564	BNIP3L/PIP4K2A/BNIP3/HMOX1/RIPK2	5
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	5/665	63/18722	0.072741252332143	0.202647995566564	CEBPB/ERO1A/PPP1R15A/LRRK2/GRINA	5
GO:1904589	regulation of protein import	5/665	63/18722	0.072741252332143	0.202647995566564	CD36/NUP58/FLNA/HCLS1/MDFIC	5
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	14/665	256/18722	0.0735467390817247	0.204454836797928	DAB2/CSNK2B/SKIL/SMURF2/CITED2/PEG10/FBN2/SDCBP/ACVRL1/FBXL15/UBE2D1/TOB1/CDKN1C/SMAD7	14
GO:0016055	Wnt signaling pathway	22/665	444/18722	0.0736398876684552	0.204454836797928	APOE/SULF2/DAB2/KLF4/NR4A2/GNAQ/CSNK2B/UBE2B/TNFAIP3/SMURF2/PTEN/RAC1/CCNY/RHOA/EGR1/EGFR/RBX1/LRRK2/WNK1/TLE3/TLR2/MDFIC	22
GO:0090277	positive regulation of peptide hormone secretion	7/665	103/18722	0.0740129323275044	0.204454836797928	HLA-DRB1/GLUL/DYNLL1/IRS2/RAC1/EGFR/KIF5B	7
GO:0042180	cellular ketone metabolic process	12/665	211/18722	0.074090696501238	0.204454836797928	APOC1/CD74/ADM/TPI1/IRS2/ANXA1/EGR1/INSIG2/VKORC1/KMO/HAGH/HSD17B1	12
GO:0009060	aerobic respiration	11/665	189/18722	0.0746989015672573	0.204454836797928	NUPR1/SDHD/IDH1/BNIP3/BLOC1S1/DNAJC15/RHOA/COA6/SDHB/CYCS/COX5B	11
GO:0002920	regulation of humoral immune response	4/665	45/18722	0.0748403122301781	0.204454836797928	FCGR2B/TREM2/SERPING1/PHB	4
GO:0003254	regulation of membrane depolarization	4/665	45/18722	0.0748403122301781	0.204454836797928	IFI6/TSPO/LRRK2/SMAD7	4
GO:0006110	regulation of glycolytic process	4/665	45/18722	0.0748403122301781	0.204454836797928	NUPR1/DDIT4/FBP1/PGAM1	4
GO:0030850	prostate gland development	4/665	45/18722	0.0748403122301781	0.204454836797928	CRIP1/PTEN/ANXA1/PSAP	4
GO:0035307	positive regulation of protein dephosphorylation	4/665	45/18722	0.0748403122301781	0.204454836797928	CD300A/CALM1/PPP1R15A/CALM3	4
GO:0045933	positive regulation of muscle contraction	4/665	45/18722	0.0748403122301781	0.204454836797928	ENO1/RHOA/RGS2/PTAFR	4
GO:0071354	cellular response to interleukin-6	4/665	45/18722	0.0748403122301781	0.204454836797928	HAMP/SPI1/SELPLG/PHB	4
GO:2000273	positive regulation of signaling receptor activity	4/665	45/18722	0.0748403122301781	0.204454836797928	NCF1/IFNGR2/EPHB2/NRP1	4
GO:0046700	heterocycle catabolic process	22/665	445/18722	0.0750150421566703	0.204454836797928	VIM/SLC11A1/OAS2/IL4I1/RNASE6/ZFP36L2/TYMP/YBX3/RNASET2/UPP1/SSB/ZFP36/ANG/MYD88/HMOX1/YBX1/HNRNPA0/TOB1/KMO/HELZ2/ELAVL1/LSM6	22
GO:0060070	canonical Wnt signaling pathway	16/665	303/18722	0.0750890222676144	0.204454836797928	APOE/SULF2/DAB2/KLF4/NR4A2/GNAQ/UBE2B/SMURF2/PTEN/CCNY/EGR1/EGFR/RBX1/LRRK2/WNK1/TLE3	16
GO:0021700	developmental maturation	15/665	280/18722	0.0753913350807001	0.204454836797928	VEGFA/CLEC7A/SNX10/NR4A2/ANG/PTEN/KLF2/RHOA/LRRK2/CDKN1A/ACVRL1/PTK2B/RB1/AGRN/C1QA	15
GO:0001945	lymph vessel development	3/665	28/18722	0.075786697432974	0.204454836797928	VEGFA/PDPN/ACVRL1	3
GO:0002507	tolerance induction	3/665	28/18722	0.075786697432974	0.204454836797928	HLA-B/TNFAIP3/HLA-E	3
GO:0002675	positive regulation of acute inflammatory response	3/665	28/18722	0.075786697432974	0.204454836797928	ADAM8/ALOX5AP/HLA-E	3
GO:0010464	regulation of mesenchymal cell proliferation	3/665	28/18722	0.075786697432974	0.204454836797928	STAT1/IRS2/LMNA	3
GO:0010575	positive regulation of vascular endothelial growth factor production	3/665	28/18722	0.075786697432974	0.204454836797928	SULF2/C5AR1/CYP1B1	3
GO:0010884	positive regulation of lipid storage	3/665	28/18722	0.075786697432974	0.204454836797928	PLIN2/CD36/MSR1	3
GO:0032801	receptor catabolic process	3/665	28/18722	0.075786697432974	0.204454836797928	APOE/DTX3L/ANXA2	3
GO:0038094	Fc-gamma receptor signaling pathway	3/665	28/18722	0.075786697432974	0.204454836797928	FCGR2B/MYO1G/RAP1A	3
GO:0061082	myeloid leukocyte cytokine production	3/665	28/18722	0.075786697432974	0.204454836797928	CD74/CD36/HMOX1	3
GO:1903649	regulation of cytoplasmic transport	3/665	28/18722	0.075786697432974	0.204454836797928	DAB2/MSN/LRRK2	3
GO:1903671	negative regulation of sprouting angiogenesis	3/665	28/18722	0.075786697432974	0.204454836797928	ALOX5/KLF2/PIK3CB	3
GO:1903672	positive regulation of sprouting angiogenesis	3/665	28/18722	0.075786697432974	0.204454836797928	VEGFA/KLF4/PKM	3
GO:0001682	tRNA 5'-leader removal	2/665	13/18722	0.0758580923652675	0.204454836797928	SSB/RPP30	2
GO:0001768	establishment of T cell polarity	2/665	13/18722	0.0758580923652675	0.204454836797928	GSN/DOCK8	2
GO:0002430	complement receptor mediated signaling pathway	2/665	13/18722	0.0758580923652675	0.204454836797928	FPR3/C5AR1	2
GO:0005513	detection of calcium ion	2/665	13/18722	0.0758580923652675	0.204454836797928	CALM1/CALM3	2
GO:0006000	fructose metabolic process	2/665	13/18722	0.0758580923652675	0.204454836797928	FBP1/ALDOA	2
GO:0006586	indolalkylamine metabolic process	2/665	13/18722	0.0758580923652675	0.204454836797928	IL4I1/KMO	2
GO:0006995	cellular response to nitrogen starvation	2/665	13/18722	0.0758580923652675	0.204454836797928	MAP1LC3B/GABARAPL2	2
GO:0008298	intracellular mRNA localization	2/665	13/18722	0.0758580923652675	0.204454836797928	ZFP36/ZNF385A	2
GO:0010917	negative regulation of mitochondrial membrane potential	2/665	13/18722	0.0758580923652675	0.204454836797928	BNIP3L/BNIP3	2
GO:0031392	regulation of prostaglandin biosynthetic process	2/665	13/18722	0.0758580923652675	0.204454836797928	CD74/ANXA1	2
GO:0032252	secretory granule localization	2/665	13/18722	0.0758580923652675	0.204454836797928	TANC2/KIF5B	2
GO:0032352	positive regulation of hormone metabolic process	2/665	13/18722	0.0758580923652675	0.204454836797928	ADM/EGR1	2
GO:0033700	phospholipid efflux	2/665	13/18722	0.0758580923652675	0.204454836797928	APOE/APOC1	2
GO:0034135	regulation of toll-like receptor 2 signaling pathway	2/665	13/18722	0.0758580923652675	0.204454836797928	TREM2/TNFAIP3	2
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	2/665	13/18722	0.0758580923652675	0.204454836797928	TREM2/TNFAIP3	2
GO:0034497	protein localization to phagophore assembly site	2/665	13/18722	0.0758580923652675	0.204454836797928	WDR45B/WIPI2	2
GO:0036005	response to macrophage colony-stimulating factor	2/665	13/18722	0.0758580923652675	0.204454836797928	TREM2/TLR2	2
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	2/665	13/18722	0.0758580923652675	0.204454836797928	TREM2/TLR2	2
GO:0042308	negative regulation of protein import into nucleus	2/665	13/18722	0.0758580923652675	0.204454836797928	CD36/MDFIC	2
GO:0042541	hemoglobin biosynthetic process	2/665	13/18722	0.0758580923652675	0.204454836797928	SLC25A37/KLF4	2
GO:0043562	cellular response to nitrogen levels	2/665	13/18722	0.0758580923652675	0.204454836797928	MAP1LC3B/GABARAPL2	2
GO:0044794	positive regulation by host of viral process	2/665	13/18722	0.0758580923652675	0.204454836797928	APOE/CFL1	2
GO:0048012	hepatocyte growth factor receptor signaling pathway	2/665	13/18722	0.0758580923652675	0.204454836797928	RAC1/NRP1	2
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	2/665	13/18722	0.0758580923652675	0.204454836797928	ZFP36/TOB1	2
GO:0072672	neutrophil extravasation	2/665	13/18722	0.0758580923652675	0.204454836797928	ADAM8/JAML	2
GO:0099150	regulation of postsynaptic specialization assembly	2/665	13/18722	0.0758580923652675	0.204454836797928	IL1RAP/ABI3	2
GO:1903651	positive regulation of cytoplasmic transport	2/665	13/18722	0.0758580923652675	0.204454836797928	DAB2/MSN	2
GO:1904478	regulation of intestinal absorption	2/665	13/18722	0.0758580923652675	0.204454836797928	HAMP/EPB41	2
GO:1904590	negative regulation of protein import	2/665	13/18722	0.0758580923652675	0.204454836797928	CD36/MDFIC	2
GO:1904995	negative regulation of leukocyte adhesion to vascular endothelial cell	2/665	13/18722	0.0758580923652675	0.204454836797928	KLF4/CXCL12	2
GO:1905939	regulation of gonad development	2/665	13/18722	0.0758580923652675	0.204454836797928	NUPR1/CITED2	2
GO:2000318	positive regulation of T-helper 17 type immune response	2/665	13/18722	0.0758580923652675	0.204454836797928	CLEC7A/NFKBIZ	2
GO:0198738	cell-cell signaling by wnt	22/665	446/18722	0.076407530504112	0.205824079460941	APOE/SULF2/DAB2/KLF4/NR4A2/GNAQ/CSNK2B/UBE2B/TNFAIP3/SMURF2/PTEN/RAC1/CCNY/RHOA/EGR1/EGFR/RBX1/LRRK2/WNK1/TLE3/TLR2/MDFIC	22
GO:0006749	glutathione metabolic process	5/665	64/18722	0.0767198817516942	0.206329985014026	CLIC2/IDH1/CLIC1/HAGH/GPX1	5
GO:0006940	regulation of smooth muscle contraction	5/665	64/18722	0.0767198817516942	0.206329985014026	DOCK4/RHOA/RGS2/PTAFR/KCNMA1	5
GO:0048857	neural nucleus development	5/665	64/18722	0.0767198817516942	0.206329985014026	YWHAH/CALM1/DYNLL1/RHOA/CALM3	5
GO:2000241	regulation of reproductive process	10/665	168/18722	0.0770634655155811	0.207141927318787	NUPR1/LHFPL2/VEGFA/DUSP1/TIMP1/UBE2B/SMURF2/CITED2/PTAFR/PHLDA2	10
GO:0018210	peptidyl-threonine modification	8/665	125/18722	0.0773570836512013	0.207818759862957	DDIT4/CALM1/CSNK2B/LRRK2/WNK1/CALM3/SMAD7/RIPK2	8
GO:0006112	energy reserve metabolic process	6/665	84/18722	0.078179164309314	0.209687235087583	IRS2/PPP1CB/PPP1R3B/PTGES3/PHLDA2/IGF2	6
GO:0010921	regulation of phosphatase activity	6/665	84/18722	0.078179164309314	0.209687235087583	CD300A/CALM1/CSNK2B/PPP1R15A/LGALS3/CALM3	6
GO:1900542	regulation of purine nucleotide metabolic process	6/665	84/18722	0.078179164309314	0.209687235087583	NUPR1/TREM2/DDIT4/FBP1/ENO1/PGAM1	6
GO:1903531	negative regulation of secretion by cell	9/665	147/18722	0.07898543603285	0.211735500044911	FCGR2B/APOE/CD300A/RSAD2/HLA-F/RAP1A/HMOX1/ANXA1/SPI1	9
GO:0006383	transcription by RNA polymerase III	4/665	46/18722	0.0797784135510872	0.213515732551913	POLR3GL/GTF3C6/IVNS1ABP/SNAPC2	4
GO:0031648	protein destabilization	4/665	46/18722	0.0797784135510872	0.213515732551913	CTSH/GSN/RNF5/PRNP	4
GO:0032924	activin receptor signaling pathway	4/665	46/18722	0.0797784135510872	0.213515732551913	CSNK2B/CITED2/ACVRL1/SMAD7	4
GO:0040029	regulation of gene expression, epigenetic	7/665	105/18722	0.0801747598331404	0.214461009887356	KLF2/CGGBP1/SPI1/KDM1B/IGF2/ZNFX1/GPX1	7
GO:0060389	pathway-restricted SMAD protein phosphorylation	5/665	65/18722	0.0808136322668952	0.215976737239273	DAB2/CSNK2B/SDCBP/ACVRL1/SMAD7	5
GO:0051146	striated muscle cell differentiation	15/665	283/18722	0.0808283161499091	0.215976737239273	VEGFA/CD9/CAPN2/HAMP/RGS2/LMNA/YBX1/PLEC/MMP14/CACYBP/IGF2/RB1/CD81/PLD3/GPX1	15
GO:0010212	response to ionizing radiation	9/665	148/18722	0.0816034727858104	0.217930822001869	HAMP/NAMPT/GRB2/ANXA1/EGR1/RHOB/TANK/CDKN1A/GPX1	9
GO:0044774	mitotic DNA integrity checkpoint signaling	6/665	85/18722	0.0817310739359488	0.218154370280164	RPS27L/RPA2/PLK3/CDKN1A/FOXN3/XPC	6
GO:0007259	receptor signaling pathway via JAK-STAT	10/665	170/18722	0.0818894303964202	0.218342526325219	CD300A/STAT1/NMI/HAMP/SOCS3/PARP9/HCLS1/PTK2B/ARL2BP/CYP1B1	10
GO:0043487	regulation of RNA stability	10/665	170/18722	0.0818894303964202	0.218342526325219	VIM/SLC11A1/ZFP36L2/YBX3/ZFP36/MYD88/YBX1/HNRNPA0/TOB1/ELAVL1	10
GO:0019359	nicotinamide nucleotide biosynthetic process	3/665	29/18722	0.0823961886255999	0.218638044564459	NAMPT/PARP9/KMO	3
GO:0019363	pyridine nucleotide biosynthetic process	3/665	29/18722	0.0823961886255999	0.218638044564459	NAMPT/PARP9/KMO	3
GO:0043153	entrainment of circadian clock by photoperiod	3/665	29/18722	0.0823961886255999	0.218638044564459	BHLHE40/PPP1CB/PER1	3
GO:0048265	response to pain	3/665	29/18722	0.0823961886255999	0.218638044564459	CAPN2/TSPO/SCN9A	3
GO:0051873	killing by host of symbiont cells	3/665	29/18722	0.0823961886255999	0.218638044564459	MYD88/GAPDH/TREM1	3
GO:0051883	killing of cells in other organism involved in symbiotic interaction	3/665	29/18722	0.0823961886255999	0.218638044564459	MYD88/GAPDH/TREM1	3
GO:0095500	acetylcholine receptor signaling pathway	3/665	29/18722	0.0823961886255999	0.218638044564459	GNAQ/LY6E/AGRN	3
GO:1902430	negative regulation of amyloid-beta formation	3/665	29/18722	0.0823961886255999	0.218638044564459	APOE/RTN3/PRNP	3
GO:1903902	positive regulation of viral life cycle	3/665	29/18722	0.0823961886255999	0.218638044564459	HLA-DRB1/LGALS1/CD74	3
GO:0015850	organic hydroxy compound transport	15/665	284/18722	0.0826955912636415	0.219315415464407	TREM2/APOE/APOC1/NFKBIA/SLC16A3/TSPO/CD36/PIP4K2A/MSR1/LY6E/OSBPL1A/SOAT1/ABCC3/ANXA2/CXCL12	15
GO:0051224	negative regulation of protein transport	8/665	127/18722	0.083059381552948	0.220162734036348	APOE/RSAD2/CD36/ANXA1/KCNE1/LRRK2/TXN/MDFIC	8
GO:2000278	regulation of DNA biosynthetic process	7/665	106/18722	0.083363848186806	0.220851985868031	DUSP1/KLF4/PTGES3/CDKN1A/ACVRL1/HNRNPA1/PTK2B	7
GO:0044270	cellular nitrogen compound catabolic process	22/665	451/18722	0.0836319612834162	0.221444244847405	VIM/SLC11A1/OAS2/IL4I1/RNASE6/ZFP36L2/TYMP/YBX3/RNASET2/UPP1/SSB/ZFP36/ANG/MYD88/HMOX1/YBX1/HNRNPA0/TOB1/KMO/HELZ2/ELAVL1/LSM6	22
GO:0030900	forebrain development	19/665	379/18722	0.0838330279325777	0.221858439203893	ATF5/CXCR4/B2M/NR4A2/SLC38A2/BNIP3/PTEN/ITGAM/FLNA/RHOA/LRRK2/UBA6/KIF5B/TYROBP/EPHB2/CXCL12/BCL2A1/SETD2/NRP1	19
GO:0009411	response to UV	9/665	149/18722	0.0842733636531718	0.222905065117756	TIMP1/CRIP1/CARD16/UBE2B/N4BP1/EGFR/CDKN1A/XPC/GPX1	9
GO:0043114	regulation of vascular permeability	4/665	47/18722	0.0848740657046089	0.224136082121098	VEGFA/APOE/ADM/PLEC	4
GO:0050798	activated T cell proliferation	4/665	47/18722	0.0848740657046089	0.224136082121098	PYCARD/IL27RA/IGF2/PRNP	4
GO:1903170	negative regulation of calcium ion transmembrane transport	4/665	47/18722	0.0848740657046089	0.224136082121098	CALM1/CLIC2/CALM3/C4orf3	4
GO:0042446	hormone biosynthetic process	5/665	66/18722	0.0850215108387623	0.224287106618179	ADM/TSPO/HSD17B11/EGR1/HSD17B1	5
GO:1905953	negative regulation of lipid localization	5/665	66/18722	0.0850215108387623	0.224287106618179	TREM2/APOC1/NFKBIA/IRS2/ABHD5	5
GO:0006140	regulation of nucleotide metabolic process	6/665	86/18722	0.0853715335443552	0.224680668263124	NUPR1/TREM2/DDIT4/FBP1/ENO1/PGAM1	6
GO:0015908	fatty acid transport	6/665	86/18722	0.0853715335443552	0.224680668263124	PLIN2/APOE/ACSL1/CD36/IRS2/ANXA1	6
GO:0034103	regulation of tissue remodeling	6/665	86/18722	0.0853715335443552	0.224680668263124	GPNMB/ADAM8/HAMP/TNFAIP3/EGFR/TFRC	6
GO:0001767	establishment of lymphocyte polarity	2/665	14/18722	0.0864817139612387	0.224680668263124	GSN/DOCK8	2
GO:0002091	negative regulation of receptor internalization	2/665	14/18722	0.0864817139612387	0.224680668263124	RIN3/SDCBP	2
GO:0002467	germinal center formation	2/665	14/18722	0.0864817139612387	0.224680668263124	TNFSF13B/TNFAIP3	2
GO:0002829	negative regulation of type 2 immune response	2/665	14/18722	0.0864817139612387	0.224680668263124	ANXA1/IL27RA	2
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	2/665	14/18722	0.0864817139612387	0.224680668263124	FCGR2B/HLA-E	2
GO:0003376	sphingosine-1-phosphate receptor signaling pathway	2/665	14/18722	0.0864817139612387	0.224680668263124	RAC1/PIK3CB	2
GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	2/665	14/18722	0.0864817139612387	0.224680668263124	UPP1/CMPK1	2
GO:0009159	deoxyribonucleoside monophosphate catabolic process	2/665	14/18722	0.0864817139612387	0.224680668263124	TYMP/UPP1	2
GO:0009173	pyrimidine ribonucleoside monophosphate metabolic process	2/665	14/18722	0.0864817139612387	0.224680668263124	UPP1/CMPK1	2
GO:0010872	regulation of cholesterol esterification	2/665	14/18722	0.0864817139612387	0.224680668263124	APOE/APOC1	2
GO:0032688	negative regulation of interferon-beta production	2/665	14/18722	0.0864817139612387	0.224680668263124	NMI/PYCARD	2
GO:0032966	negative regulation of collagen biosynthetic process	2/665	14/18722	0.0864817139612387	0.224680668263124	ERRFI1/RAP1A	2
GO:0035563	positive regulation of chromatin binding	2/665	14/18722	0.0864817139612387	0.224680668263124	DTX3L/PARP9	2
GO:0035641	locomotory exploration behavior	2/665	14/18722	0.0864817139612387	0.224680668263124	APOE/LRRK2	2
GO:0043558	regulation of translational initiation in response to stress	2/665	14/18722	0.0864817139612387	0.224680668263124	EIF2AK2/PPP1R15A	2
GO:0043951	negative regulation of cAMP-mediated signaling	2/665	14/18722	0.0864817139612387	0.224680668263124	UBE2B/RGS2	2
GO:0045837	negative regulation of membrane potential	2/665	14/18722	0.0864817139612387	0.224680668263124	BNIP3L/BNIP3	2
GO:0046049	UMP metabolic process	2/665	14/18722	0.0864817139612387	0.224680668263124	UPP1/CMPK1	2
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	2/665	14/18722	0.0864817139612387	0.224680668263124	CXCR4/CXCL12	2
GO:0051764	actin crosslink formation	2/665	14/18722	0.0864817139612387	0.224680668263124	FLNA/MARCKS	2
GO:0060081	membrane hyperpolarization	2/665	14/18722	0.0864817139612387	0.224680668263124	SOD2/KCNQ3	2
GO:0060841	venous blood vessel development	2/665	14/18722	0.0864817139612387	0.224680668263124	VEGFA/ACVRL1	2
GO:0070141	response to UV-A	2/665	14/18722	0.0864817139612387	0.224680668263124	TIMP1/EGFR	2
GO:0070942	neutrophil mediated cytotoxicity	2/665	14/18722	0.0864817139612387	0.224680668263124	MYD88/TREM1	2
GO:1902916	positive regulation of protein polyubiquitination	2/665	14/18722	0.0864817139612387	0.224680668263124	NMI/UBE2D1	2
GO:2001171	positive regulation of ATP biosynthetic process	2/665	14/18722	0.0864817139612387	0.224680668263124	TREM2/ENO1	2
GO:0000018	regulation of DNA recombination	7/665	107/18722	0.0866247972400091	0.224817358894436	TERF2IP/UBE2B/RPA2/IL7R/IL27RA/TFRC/SETD2	7
GO:0005976	polysaccharide metabolic process	7/665	107/18722	0.0866247972400091	0.224817358894436	IRS2/PPP1CB/PPP1R3B/B3GNT7/PTGES3/PHLDA2/IGF2	7
GO:0050851	antigen receptor-mediated signaling pathway	13/665	240/18722	0.0872241393144817	0.226254682877335	FCGR2B/HLA-DRB1/HLA-DQB1/HLA-A/HLA-DPB1/CD300A/LGALS3/GBP1/NFKBIZ/WNK1/CD81/RIPK2/PRNP	13
GO:0006099	tricarboxylic acid cycle	3/665	30/18722	0.0892438625125034	0.230651064319887	SDHD/IDH1/SDHB	3
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	3/665	30/18722	0.0892438625125034	0.230651064319887	CALM1/CALM3/RIPK2	3
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	3/665	30/18722	0.0892438625125034	0.230651064319887	CALM1/CLIC2/CALM3	3
GO:0045577	regulation of B cell differentiation	3/665	30/18722	0.0892438625125034	0.230651064319887	IL4I1/ZFP36L2/MMP14	3
GO:0046825	regulation of protein export from nucleus	3/665	30/18722	0.0892438625125034	0.230651064319887	IFI27/TXN/CAMK1	3
GO:0051491	positive regulation of filopodium assembly	3/665	30/18722	0.0892438625125034	0.230651064319887	RALA/AGRN/NRP1	3
GO:0070168	negative regulation of biomineral tissue development	3/665	30/18722	0.0892438625125034	0.230651064319887	SRGN/ECM1/PTK2B	3
GO:0044843	cell cycle G1/S phase transition	13/665	241/18722	0.0893781936534092	0.230758245432438	GPNMB/KLF4/PSME2/RPS27L/PTEN/ANXA1/EIF4EBP1/EGFR/RPA2/PLK3/CDKN1A/RB1/EIF4E	13
GO:0060047	heart contraction	13/665	241/18722	0.0893781936534092	0.230758245432438	CXCR4/CALM1/ADORA3/ADM/TMIGD3/GSN/CLIC2/FLNA/KCNE1/RGS2/CALM3/SMAD7/GPX1	13
GO:0009306	protein secretion	18/665	359/18722	0.0904315797260477	0.233356672501795	HLA-DRB1/TREM2/APOE/ADAM8/ALOX5/RSAD2/GLUL/DYNLL1/RAB8A/IRS2/ANG/RAC1/ANXA1/EGFR/KIF5B/TMEM167A/RAB13/TLR2	18
GO:0048639	positive regulation of developmental growth	10/665	174/18722	0.0920855746580162	0.237501456175579	CXCR4/VEGFA/YBX3/HAMP/IGF2/FN1/AGRN/CXCL12/SMAD7/NRP1	10
GO:0035592	establishment of protein localization to extracellular region	18/665	360/18722	0.0922168300525249	0.237716621037888	HLA-DRB1/TREM2/APOE/ADAM8/ALOX5/RSAD2/GLUL/DYNLL1/RAB8A/IRS2/ANG/RAC1/ANXA1/EGFR/KIF5B/TMEM167A/RAB13/TLR2	18
GO:0007346	regulation of mitotic cell cycle	22/665	457/18722	0.0928840263785806	0.239270706292142	GPNMB/DUSP1/ZFP36L2/BTG1/KLF4/PSME2/RPS27L/PTEN/ANXA1/EIF4EBP1/EGFR/RPA2/SDCBP/PLK3/DYNLT3/CDKN1A/FOXN3/IGF2/RB1/EIF4E/CDKN1C/XPC	22
GO:0009144	purine nucleoside triphosphate metabolic process	6/665	88/18722	0.0929159885601277	0.239270706292142	TREM2/ALDOA/ENO1/RHOA/LRRK2/GUK1	6
GO:0032410	negative regulation of transporter activity	7/665	109/18722	0.0933612026687789	0.240292686309597	CALM1/CLIC2/PTEN/KCNE1/CALM3/C4orf3/EPHB2	7
GO:1902305	regulation of sodium ion transmembrane transport	5/665	68/18722	0.093775050837998	0.24123292063398	YWHAH/FXYD5/GLRX/WNK1/KIF5B	5
GO:1904950	negative regulation of establishment of protein localization	8/665	131/18722	0.0951868774249964	0.243595553374559	APOE/RSAD2/CD36/ANXA1/KCNE1/LRRK2/TXN/MDFIC	8
GO:0046394	carboxylic acid biosynthetic process	16/665	314/18722	0.095261369649501	0.243595553374559	APOC1/CD74/ALOX5/SCD/GLUL/SLC1A3/MIF/ALOX5AP/ANXA1/PTGES3/RBP1/OSBPL1A/GATM/INSIG2/HACD4/KMO	16
GO:0060249	anatomical structure homeostasis	16/665	314/18722	0.095261369649501	0.243595553374559	VEGFA/B2M/LYZ/CTSH/ADAM8/OAS1/ACP5/ALDOA/SNX10/HAMP/TNFAIP3/RAC1/EGFR/PTK2B/TFRC/RB1	16
GO:0006692	prostanoid metabolic process	4/665	49/18722	0.0955267069470858	0.243595553374559	CD74/MIF/ANXA1/PTGES3	4
GO:0006693	prostaglandin metabolic process	4/665	49/18722	0.0955267069470858	0.243595553374559	CD74/MIF/ANXA1/PTGES3	4
GO:0006953	acute-phase response	4/665	49/18722	0.0955267069470858	0.243595553374559	PLSCR1/CEBPB/HAMP/FN1	4
GO:0009395	phospholipid catabolic process	4/665	49/18722	0.0955267069470858	0.243595553374559	APOC1/IDH1/GPCPD1/PLBD1	4
GO:0009409	response to cold	4/665	49/18722	0.0955267069470858	0.243595553374559	NFKBIA/ADM/SOD2/FOS	4
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	4/665	49/18722	0.0955267069470858	0.243595553374559	DAB2/CSNK2B/SDCBP/ACVRL1	4
GO:0042304	regulation of fatty acid biosynthetic process	4/665	49/18722	0.0955267069470858	0.243595553374559	APOC1/CD74/ANXA1/INSIG2	4
GO:0043330	response to exogenous dsRNA	4/665	49/18722	0.0955267069470858	0.243595553374559	IFIT1/NFKBIA/IFIH1/RIPK2	4
GO:0043457	regulation of cellular respiration	4/665	49/18722	0.0955267069470858	0.243595553374559	NUPR1/BNIP3/DNAJC15/RHOA	4
GO:0060964	regulation of gene silencing by miRNA	4/665	49/18722	0.0955267069470858	0.243595553374559	ZFP36/HIF1A-AS2/EGFR/ELAVL1	4
GO:0070169	positive regulation of biomineral tissue development	4/665	49/18722	0.0955267069470858	0.243595553374559	ISG15/ALOX5/CEBPB/FBN2	4
GO:0070741	response to interleukin-6	4/665	49/18722	0.0955267069470858	0.243595553374559	HAMP/SPI1/SELPLG/PHB	4
GO:1901799	negative regulation of proteasomal protein catabolic process	4/665	49/18722	0.0955267069470858	0.243595553374559	N4BP1/GABARAPL2/SDCBP/CAMLG	4
GO:1904894	positive regulation of receptor signaling pathway via STAT	4/665	49/18722	0.0955267069470858	0.243595553374559	CD300A/IL7R/PTK2B/CYP1B1	4
GO:0048167	regulation of synaptic plasticity	11/665	198/18722	0.0958695191859474	0.243915397580026	APOE/YWHAH/RAB8A/PTEN/STX3/PTK2B/SQSTM1/TYROBP/EPHB2/SIPA1L1/PRNP	11
GO:0002063	chondrocyte development	3/665	31/18722	0.0963208144656424	0.243915397580026	SULF2/ECM1/SMAD7	3
GO:0008045	motor neuron axon guidance	3/665	31/18722	0.0963208144656424	0.243915397580026	ALCAM/RAC1/NRP1	3
GO:0016577	histone demethylation	3/665	31/18722	0.0963208144656424	0.243915397580026	UBE2B/KDM1B/JARID2	3
GO:0065005	protein-lipid complex assembly	3/665	31/18722	0.0963208144656424	0.243915397580026	APOE/APOC1/SOAT1	3
GO:0071168	protein localization to chromatin	3/665	31/18722	0.0963208144656424	0.243915397580026	SPI1/RB1/SETD2	3
GO:0097106	postsynaptic density organization	3/665	31/18722	0.0963208144656424	0.243915397580026	IL1RAP/PTEN/ABI3	3
GO:0110150	negative regulation of biomineralization	3/665	31/18722	0.0963208144656424	0.243915397580026	SRGN/ECM1/PTK2B	3
GO:1905144	response to acetylcholine	3/665	31/18722	0.0963208144656424	0.243915397580026	GNAQ/LY6E/AGRN	3
GO:1905145	cellular response to acetylcholine	3/665	31/18722	0.0963208144656424	0.243915397580026	GNAQ/LY6E/AGRN	3
GO:0014910	regulation of smooth muscle cell migration	6/665	89/18722	0.0968187375148242	0.243915397580026	DOCK4/RHOA/TRIB1/PLAU/S100A11/NRP1	6
GO:0003014	renal system process	7/665	110/18722	0.0968359956529401	0.243915397580026	SULF2/SGK1/ADM/GSN/RRM2B/RHOA/KCNMA1	7
GO:0014812	muscle cell migration	7/665	110/18722	0.0968359956529401	0.243915397580026	DOCK4/ANXA1/RHOA/TRIB1/PLAU/S100A11/NRP1	7
GO:1904659	glucose transmembrane transport	7/665	110/18722	0.0968359956529401	0.243915397580026	SLC2A5/HK2/IRS2/RAP1A/PEA15/SLC2A3/PPBP	7
GO:0002730	regulation of dendritic cell cytokine production	2/665	15/18722	0.0975170814872257	0.243915397580026	CLEC7A/BST2	2
GO:0006089	lactate metabolic process	2/665	15/18722	0.0975170814872257	0.243915397580026	LDHA/HAGH	2
GO:0006878	cellular copper ion homeostasis	2/665	15/18722	0.0975170814872257	0.243915397580026	SCO2/PRNP	2
GO:0009263	deoxyribonucleotide biosynthetic process	2/665	15/18722	0.0975170814872257	0.243915397580026	RRM2B/GUK1	2
GO:0010713	negative regulation of collagen metabolic process	2/665	15/18722	0.0975170814872257	0.243915397580026	ERRFI1/RAP1A	2
GO:0010940	positive regulation of necrotic cell death	2/665	15/18722	0.0975170814872257	0.243915397580026	TSPO/BNIP3	2
GO:0015697	quaternary ammonium group transport	2/665	15/18722	0.0975170814872257	0.243915397580026	SLC38A2/SLC25A19	2
GO:0032486	Rap protein signal transduction	2/665	15/18722	0.0975170814872257	0.243915397580026	RAP1A/RAPGEF1	2
GO:0032488	Cdc42 protein signal transduction	2/665	15/18722	0.0975170814872257	0.243915397580026	APOE/NRP1	2
GO:0034384	high-density lipoprotein particle clearance	2/665	15/18722	0.0975170814872257	0.243915397580026	TREM2/APOE	2
GO:0042159	lipoprotein catabolic process	2/665	15/18722	0.0975170814872257	0.243915397580026	APOE/CTSD	2
GO:0042976	activation of Janus kinase activity	2/665	15/18722	0.0975170814872257	0.243915397580026	CD300A/PTK2B	2
GO:0045475	locomotor rhythm	2/665	15/18722	0.0975170814872257	0.243915397580026	PTEN/EGR1	2
GO:0045725	positive regulation of glycogen biosynthetic process	2/665	15/18722	0.0975170814872257	0.243915397580026	IRS2/IGF2	2
GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening	2/665	15/18722	0.0975170814872257	0.243915397580026	ZFP36/TOB1	2
GO:0060766	negative regulation of androgen receptor signaling pathway	2/665	15/18722	0.0975170814872257	0.243915397580026	DAB2/PHB	2
GO:0070207	protein homotrimerization	2/665	15/18722	0.0975170814872257	0.243915397580026	MIF/ALOX5AP	2
GO:0071474	cellular hyperosmotic response	2/665	15/18722	0.0975170814872257	0.243915397580026	YBX3/ERRFI1	2
GO:1901660	calcium ion export	2/665	15/18722	0.0975170814872257	0.243915397580026	CALM1/CALM3	2
GO:1901841	regulation of high voltage-gated calcium channel activity	2/665	15/18722	0.0975170814872257	0.243915397580026	CALM1/CALM3	2
GO:1902902	negative regulation of autophagosome assembly	2/665	15/18722	0.0975170814872257	0.243915397580026	NUPR1/LRRK2	2
GO:1904889	regulation of excitatory synapse assembly	2/665	15/18722	0.0975170814872257	0.243915397580026	IL1RAP/ABI3	2
GO:2000345	regulation of hepatocyte proliferation	2/665	15/18722	0.0975170814872257	0.243915397580026	SULF2/TNFAIP3	2
GO:2001279	regulation of unsaturated fatty acid biosynthetic process	2/665	15/18722	0.0975170814872257	0.243915397580026	CD74/ANXA1	2
GO:0010611	regulation of cardiac muscle hypertrophy	5/665	69/18722	0.0983181103875891	0.245626687530865	ERRFI1/HAMP/RGS2/LMNA/JARID2	5
GO:0033344	cholesterol efflux	5/665	69/18722	0.0983181103875891	0.245626687530865	TREM2/APOE/APOC1/NFKBIA/SOAT1	5
GO:0045667	regulation of osteoblast differentiation	8/665	132/18722	0.0983684519905856	0.245626687530865	JUND/IFITM1/CEBPB/CLIC1/RASSF2/HIF1A-AS2/FBN2/TOB1	8
GO:0007605	sensory perception of sound	9/665	154/18722	0.0983989406185015	0.245626687530865	SLC1A3/KCNE1/GABRB2/TIMM8B/DIAPH1/HEXB/SCARB2/TIMM10/GPX1	9
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	20/665	412/18722	0.0989835146603492	0.246961881456795	IFI27/DAB2/SUMO2/UBE2B/N4BP1/SMURF2/PPP2CB/TRIB1/SPOP/RBX1/LRRK2/SDCBP/PSMC6/PLK3/FBXL15/RNF187/RNF5/CAMLG/FBXL5/SMAD7	20
GO:0016053	organic acid biosynthetic process	16/665	316/18722	0.0992629567854605	0.247534819480049	APOC1/CD74/ALOX5/SCD/GLUL/SLC1A3/MIF/ALOX5AP/ANXA1/PTGES3/RBP1/OSBPL1A/GATM/INSIG2/HACD4/KMO	16
GO:0030324	lung development	10/665	177/18722	0.10020820921024	0.249766699987409	VEGFA/CTSH/ERRFI1/PDPN/EIF4EBP1/KLF2/PTGES3/EGFR/MMP14/EIF4E	10
GO:0090288	negative regulation of cellular response to growth factor stimulus	7/665	111/18722	0.100381323964771	0.250072771982412	SULF2/SKIL/SMURF2/UBE2D1/PIK3CB/TOB1/SMAD7	7
GO:0002028	regulation of sodium ion transport	6/665	90/18722	0.100807546964739	0.250131556872069	YWHAH/FXYD5/GLRX/WNK1/KIF5B/PER1	6
GO:0030901	midbrain development	6/665	90/18722	0.100807546964739	0.250131556872069	YWHAH/CALM1/NR4A2/DYNLL1/RHOA/CALM3	6
GO:0034644	cellular response to UV	6/665	90/18722	0.100807546964739	0.250131556872069	TIMP1/CRIP1/CARD16/N4BP1/CDKN1A/XPC	6
GO:0035304	regulation of protein dephosphorylation	6/665	90/18722	0.100807546964739	0.250131556872069	CD300A/CALM1/CSNK2B/PPP1R15A/LGALS3/CALM3	6
GO:0045638	negative regulation of myeloid cell differentiation	6/665	90/18722	0.100807546964739	0.250131556872069	NFKBIA/ZFP36/MAFB/C1QC/TRIB1/PTK2B	6
GO:0061097	regulation of protein tyrosine kinase activity	6/665	90/18722	0.100807546964739	0.250131556872069	SH3BP5/ERRFI1/LILRA5/NCF1/ABI1/PRNP	6
GO:0097581	lamellipodium organization	6/665	90/18722	0.100807546964739	0.250131556872069	CD44/ABI1/RAC1/PARVB/PDPN/ABI3	6
GO:1904705	regulation of vascular associated smooth muscle cell proliferation	6/665	90/18722	0.100807546964739	0.250131556872069	JUN/SOD2/PTEN/HMOX1/RHOA/CDKN1A	6
GO:0010665	regulation of cardiac muscle cell apoptotic process	4/665	50/18722	0.101077538021511	0.250176974087107	NUPR1/CAPN2/BNIP3/PTEN	4
GO:0050873	brown fat cell differentiation	4/665	50/18722	0.101077538021511	0.250176974087107	CEBPB/ERO1A/BNIP3/RGS2	4
GO:0071709	membrane assembly	4/665	50/18722	0.101077538021511	0.250176974087107	S100A10/PTEN/ANXA2/EPHB2	4
GO:0110151	positive regulation of biomineralization	4/665	50/18722	0.101077538021511	0.250176974087107	ISG15/ALOX5/CEBPB/FBN2	4
GO:1904036	negative regulation of epithelial cell apoptotic process	4/665	50/18722	0.101077538021511	0.250176974087107	NUPR1/TNFAIP3/HMOX1/ANGPTL4	4
GO:0002548	monocyte chemotaxis	5/665	70/18722	0.102970103395792	0.254696316739054	DUSP1/LGALS3/ANXA1/CCL13/CXCL12	5
GO:0048015	phosphatidylinositol-mediated signaling	10/665	178/18722	0.103005955059456	0.254696316739054	TREM2/KLF4/NCF1/PTEN/HCLS1/EGFR/PTAFR/PIK3CB/FN1/HAX1	10
GO:0006026	aminoglycan catabolic process	3/665	32/18722	0.103617893402135	0.254941054558718	CD44/IDS/LYVE1	3
GO:0010743	regulation of macrophage derived foam cell differentiation	3/665	32/18722	0.103617893402135	0.254941054558718	NFKBIA/CD36/MSR1	3
GO:0019934	cGMP-mediated signaling	3/665	32/18722	0.103617893402135	0.254941054558718	APOE/CD36/PTK2B	3
GO:0033687	osteoblast proliferation	3/665	32/18722	0.103617893402135	0.254941054558718	EIF2AK2/JUNB/RHOA	3
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	3/665	32/18722	0.103617893402135	0.254941054558718	LARP7/EAF1/EAPP	3
GO:0048841	regulation of axon extension involved in axon guidance	3/665	32/18722	0.103617893402135	0.254941054558718	VEGFA/CXCL12/NRP1	3
GO:0072525	pyridine-containing compound biosynthetic process	3/665	32/18722	0.103617893402135	0.254941054558718	NAMPT/PARP9/KMO	3
GO:0097345	mitochondrial outer membrane permeabilization	3/665	32/18722	0.103617893402135	0.254941054558718	BNIP3L/BNIP3/BLOC1S2	3
GO:1901185	negative regulation of ERBB signaling pathway	3/665	32/18722	0.103617893402135	0.254941054558718	ERRFI1/PTPN12/EGFR	3
GO:1901532	regulation of hematopoietic progenitor cell differentiation	3/665	32/18722	0.103617893402135	0.254941054558718	EIF2AK2/SPI1/SOS2	3
GO:0048640	negative regulation of developmental growth	7/665	112/18722	0.103996733177057	0.255746543240957	CGA/CITED2/PTEN/RGS2/CDKN1A/JARID2/NRP1	7
GO:1990874	vascular associated smooth muscle cell proliferation	6/665	91/18722	0.104881612141601	0.257736396982544	JUN/SOD2/PTEN/HMOX1/RHOA/CDKN1A	6
GO:0042552	myelination	8/665	134/18722	0.104909603842191	0.257736396982544	CXCR4/CD9/NDRG1/TYMP/PTEN/PLEC/HEXB/TLR2	8
GO:0021537	telencephalon development	13/665	248/18722	0.105378043234667	0.258759325531766	ATF5/CXCR4/SLC38A2/BNIP3/PTEN/FLNA/RHOA/LRRK2/UBA6/KIF5B/EPHB2/CXCL12/BCL2A1	13
GO:0014009	glial cell proliferation	4/665	51/18722	0.106773631984111	0.261540143401198	TREM2/TSPO/EGFR/PTK2B	4
GO:0032873	negative regulation of stress-activated MAPK cascade	4/665	51/18722	0.106773631984111	0.261540143401198	TREM2/DUSP1/AIDA/PER1	4
GO:0045104	intermediate filament cytoskeleton organization	4/665	51/18722	0.106773631984111	0.261540143401198	VIM/PLEC/KRT18/DST	4
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	4/665	51/18722	0.106773631984111	0.261540143401198	TREM2/DUSP1/AIDA/PER1	4
GO:0071622	regulation of granulocyte chemotaxis	4/665	51/18722	0.106773631984111	0.261540143401198	CD74/CXCL8/C5AR1/RAC1	4
GO:0007034	vacuolar transport	9/665	157/18722	0.107491108847857	0.262150401665842	DTX3L/RHOB/LRRK2/GRN/SCARB2/VTA1/CHMP5/VPS13A/PSAP	9
GO:0044344	cellular response to fibroblast growth factor stimulus	7/665	113/18722	0.10768172122976	0.262150401665842	SULF2/ZFP36L2/CXCL8/CD44/ZFP36/SHOC2/NR4A1	7
GO:1901988	negative regulation of cell cycle phase transition	13/665	249/18722	0.107795218472693	0.262150401665842	ATF5/GPNMB/DUSP1/ZFP36L2/KLF4/RPS27L/PTEN/RPA2/PLK3/CDKN1A/FOXN3/RB1/XPC	13
GO:0071897	DNA biosynthetic process	10/665	180/18722	0.108736031311401	0.262150401665842	DUSP1/KLF4/TERF2IP/NOP10/PTGES3/CDKN1A/ACVRL1/HNRNPA1/PTK2B/PHB	10
GO:0002371	dendritic cell cytokine production	2/665	16/18722	0.108921645762568	0.262150401665842	CLEC7A/BST2	2
GO:0002693	positive regulation of cellular extravasation	2/665	16/18722	0.108921645762568	0.262150401665842	ADAM8/PTAFR	2
GO:0002921	negative regulation of humoral immune response	2/665	16/18722	0.108921645762568	0.262150401665842	FCGR2B/SERPING1	2
GO:0003084	positive regulation of systemic arterial blood pressure	2/665	16/18722	0.108921645762568	0.262150401665842	RHOA/WNK1	2
GO:0005980	glycogen catabolic process	2/665	16/18722	0.108921645762568	0.262150401665842	PPP1CB/PPP1R3B	2
GO:0006206	pyrimidine nucleobase metabolic process	2/665	16/18722	0.108921645762568	0.262150401665842	TYMP/CMPK1	2
GO:0006349	regulation of gene expression by genetic imprinting	2/665	16/18722	0.108921645762568	0.262150401665842	KDM1B/IGF2	2
GO:0006828	manganese ion transport	2/665	16/18722	0.108921645762568	0.262150401665842	SLC11A1/ATP2C1	2
GO:0009074	aromatic amino acid family catabolic process	2/665	16/18722	0.108921645762568	0.262150401665842	IL4I1/KMO	2
GO:0009299	mRNA transcription	2/665	16/18722	0.108921645762568	0.262150401665842	C5AR1/FLNA	2
GO:0009415	response to water	2/665	16/18722	0.108921645762568	0.262150401665842	CD9/PLEC	2
GO:0010649	regulation of cell communication by electrical coupling	2/665	16/18722	0.108921645762568	0.262150401665842	CALM1/CALM3	2
GO:0010919	regulation of inositol phosphate biosynthetic process	2/665	16/18722	0.108921645762568	0.262150401665842	PTAFR/PTK2B	2
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	2/665	16/18722	0.108921645762568	0.262150401665842	LARP7/EAPP	2
GO:0034375	high-density lipoprotein particle remodeling	2/665	16/18722	0.108921645762568	0.262150401665842	APOE/APOC1	2
GO:0035751	regulation of lysosomal lumen pH	2/665	16/18722	0.108921645762568	0.262150401665842	LRRK2/GRN	2
GO:0045342	MHC class II biosynthetic process	2/665	16/18722	0.108921645762568	0.262150401665842	SLC11A1/SPI1	2
GO:0045779	negative regulation of bone resorption	2/665	16/18722	0.108921645762568	0.262150401665842	HAMP/TNFAIP3	2
GO:0048385	regulation of retinoic acid receptor signaling pathway	2/665	16/18722	0.108921645762568	0.262150401665842	KLF2/DHRS3	2
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	2/665	16/18722	0.108921645762568	0.262150401665842	CXCR4/CXCL12	2
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	2/665	16/18722	0.108921645762568	0.262150401665842	APOE/ADAM8	2
GO:0061684	chaperone-mediated autophagy	2/665	16/18722	0.108921645762568	0.262150401665842	PLK3/CTSA	2
GO:0070365	hepatocyte differentiation	2/665	16/18722	0.108921645762568	0.262150401665842	ANXA1/KRT18	2
GO:0072148	epithelial cell fate commitment	2/665	16/18722	0.108921645762568	0.262150401665842	PDPN/NRP1	2
GO:0090520	sphingolipid mediated signaling pathway	2/665	16/18722	0.108921645762568	0.262150401665842	RAC1/PIK3CB	2
GO:0097202	activation of cysteine-type endopeptidase activity	2/665	16/18722	0.108921645762568	0.262150401665842	PYCARD/RIPK2	2
GO:0098969	neurotransmitter receptor transport to postsynaptic membrane	2/665	16/18722	0.108921645762568	0.262150401665842	RAB8A/STX3	2
GO:0099116	tRNA 5'-end processing	2/665	16/18722	0.108921645762568	0.262150401665842	SSB/RPP30	2
GO:1903236	regulation of leukocyte tethering or rolling	2/665	16/18722	0.108921645762568	0.262150401665842	PTAFR/CXCL12	2
GO:1905874	regulation of postsynaptic density organization	2/665	16/18722	0.108921645762568	0.262150401665842	IL1RAP/ABI3	2
GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	2/665	16/18722	0.108921645762568	0.262150401665842	DTX3L/PARP9	2
GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	2/665	16/18722	0.108921645762568	0.262150401665842	GSN/PLAUR	2
GO:0035249	synaptic transmission, glutamatergic	6/665	92/18722	0.109040059017231	0.262308370433513	GLUL/EGFR/LRRK2/TPRG1L/PTK2B/KMO	6
GO:0019439	aromatic compound catabolic process	22/665	467/18722	0.10973565163677	0.263853985793298	VIM/SLC11A1/OAS2/IL4I1/RNASE6/ZFP36L2/TYMP/YBX3/RNASET2/UPP1/SSB/ZFP36/ANG/MYD88/HMOX1/YBX1/HNRNPA0/TOB1/KMO/HELZ2/ELAVL1/LSM6	22
GO:0006482	protein demethylation	3/665	33/18722	0.111125750812776	0.265654151774651	UBE2B/KDM1B/JARID2	3
GO:0008214	protein dealkylation	3/665	33/18722	0.111125750812776	0.265654151774651	UBE2B/KDM1B/JARID2	3
GO:0009648	photoperiodism	3/665	33/18722	0.111125750812776	0.265654151774651	BHLHE40/PPP1CB/PER1	3
GO:0010165	response to X-ray	3/665	33/18722	0.111125750812776	0.265654151774651	HAMP/ANXA1/CDKN1A	3
GO:0010737	protein kinase A signaling	3/665	33/18722	0.111125750812776	0.265654151774651	MIF/LRRK2/RAB13	3
GO:0010984	regulation of lipoprotein particle clearance	3/665	33/18722	0.111125750812776	0.265654151774651	TREM2/APOC1/ANXA2	3
GO:0018345	protein palmitoylation	3/665	33/18722	0.111125750812776	0.265654151774651	GLUL/ZDHHC20/GOLGA7	3
GO:0019362	pyridine nucleotide metabolic process	3/665	33/18722	0.111125750812776	0.265654151774651	NAMPT/PARP9/KMO	3
GO:0046496	nicotinamide nucleotide metabolic process	3/665	33/18722	0.111125750812776	0.265654151774651	NAMPT/PARP9/KMO	3
GO:0099084	postsynaptic specialization organization	3/665	33/18722	0.111125750812776	0.265654151774651	IL1RAP/PTEN/ABI3	3
GO:1902992	negative regulation of amyloid precursor protein catabolic process	3/665	33/18722	0.111125750812776	0.265654151774651	APOE/RTN3/PRNP	3
GO:1904031	positive regulation of cyclin-dependent protein kinase activity	3/665	33/18722	0.111125750812776	0.265654151774651	CCNY/EGFR/CDKN1A	3
GO:0007041	lysosomal transport	7/665	114/18722	0.111435739318861	0.266011346981142	DTX3L/RHOB/LRRK2/GRN/SCARB2/CHMP5/PSAP	7
GO:0008645	hexose transmembrane transport	7/665	114/18722	0.111435739318861	0.266011346981142	SLC2A5/HK2/IRS2/RAP1A/PEA15/SLC2A3/PPBP	7
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	7/665	114/18722	0.111435739318861	0.266011346981142	DAB2/CSNK2B/CITED2/SDCBP/ACVRL1/FBXL15/CDKN1C	7
GO:0030323	respiratory tube development	10/665	181/18722	0.111668054668651	0.266097556780486	VEGFA/CTSH/ERRFI1/PDPN/EIF4EBP1/KLF2/PTGES3/EGFR/MMP14/EIF4E	10
GO:0007272	ensheathment of neurons	8/665	136/18722	0.111686016789556	0.266097556780486	CXCR4/CD9/NDRG1/TYMP/PTEN/PLEC/HEXB/TLR2	8
GO:0008366	axon ensheathment	8/665	136/18722	0.111686016789556	0.266097556780486	CXCR4/CD9/NDRG1/TYMP/PTEN/PLEC/HEXB/TLR2	8
GO:0098876	vesicle-mediated transport to the plasma membrane	8/665	136/18722	0.111686016789556	0.266097556780486	RAB8A/VAMP5/GOLGA7/KRT18/STX3/RAB13/RAB31/ATP2C1	8
GO:0048511	rhythmic process	15/665	298/18722	0.111748363809409	0.26611852809428	ATF5/JUND/JUN/GNAQ/AHR/BHLHE40/NFIL3/KLF10/NAMPT/PPP1CB/PTEN/EGR1/EGFR/KLF9/PER1	15
GO:0014743	regulation of muscle hypertrophy	5/665	72/18722	0.112594460518062	0.267022432122603	ERRFI1/HAMP/RGS2/LMNA/JARID2	5
GO:0055021	regulation of cardiac muscle tissue growth	5/665	72/18722	0.112594460518062	0.267022432122603	HAMP/CITED2/PTEN/RGS2/JARID2	5
GO:0010662	regulation of striated muscle cell apoptotic process	4/665	52/18722	0.112611472380076	0.267022432122603	NUPR1/CAPN2/BNIP3/PTEN	4
GO:0010718	positive regulation of epithelial to mesenchymal transition	4/665	52/18722	0.112611472380076	0.267022432122603	DAB2/PDPN/GLIPR2/SDCBP	4
GO:0045010	actin nucleation	4/665	52/18722	0.112611472380076	0.267022432122603	GSN/GMFG/ARPC4/IQGAP2	4
GO:0045103	intermediate filament-based process	4/665	52/18722	0.112611472380076	0.267022432122603	VIM/PLEC/KRT18/DST	4
GO:0048260	positive regulation of receptor-mediated endocytosis	4/665	52/18722	0.112611472380076	0.267022432122603	VEGFA/B2M/DAB2/ANXA2	4
GO:0060071	Wnt signaling pathway, planar cell polarity pathway	4/665	52/18722	0.112611472380076	0.267022432122603	DAB2/SMURF2/RAC1/RHOA	4
GO:0060147	regulation of posttranscriptional gene silencing	4/665	52/18722	0.112611472380076	0.267022432122603	ZFP36/HIF1A-AS2/EGFR/ELAVL1	4
GO:0003015	heart process	13/665	251/18722	0.112727771101497	0.267170730746038	CXCR4/CALM1/ADORA3/ADM/TMIGD3/GSN/CLIC2/FLNA/KCNE1/RGS2/CALM3/SMAD7/GPX1	13
GO:0007589	body fluid secretion	6/665	93/18722	0.113281946277169	0.268228333967379	OAS2/VEGFA/HK2/EGFR/WNK1/ANXA2	6
GO:0060349	bone morphogenesis	6/665	93/18722	0.113281946277169	0.268228333967379	ACP5/CITED2/DHRS3/INSIG2/MMP14/FOXN3	6
GO:0010639	negative regulation of organelle organization	17/665	347/18722	0.11383188637608	0.269402131090057	NUPR1/CAPG/DUSP1/MYADM/TSPO/TERF2IP/GSN/GMFG/BNIP3/MAPRE1/LMNA/VAT1/LRRK2/TMSB10/HNRNPA1/TFRC/GPX1	17
GO:1901990	regulation of mitotic cell cycle phase transition	15/665	299/18722	0.114031807361797	0.269746826553131	GPNMB/DUSP1/ZFP36L2/KLF4/PSME2/RPS27L/PTEN/ANXA1/EGFR/RPA2/PLK3/CDKN1A/FOXN3/RB1/XPC	15
GO:0048017	inositol lipid-mediated signaling	10/665	182/18722	0.114644498053069	0.271067152865723	TREM2/KLF4/NCF1/PTEN/HCLS1/EGFR/PTAFR/PIK3CB/FN1/HAX1	10
GO:0007586	digestion	8/665	137/18722	0.11516154187719	0.272160182182423	SLC2A5/SGK1/TYMP/SNX10/CD36/HAMP/EPB41/WNK1	8
GO:0090316	positive regulation of intracellular protein transport	9/665	160/18722	0.117039622433085	0.276467168960282	ITGAM/FLNA/HCLS1/PLK3/KIF5B/CAMK1/OAZ1/CD81/PRNP	9
GO:0035924	cellular response to vascular endothelial growth factor stimulus	5/665	73/18722	0.117563355658685	0.277392060765902	VEGFA/ANXA1/PIK3CB/NR4A1/NRP1	5
GO:0099518	vesicle cytoskeletal trafficking	5/665	73/18722	0.117563355658685	0.277392060765902	MYO1G/TANC2/BLOC1S1/BLOC1S2/KIF5B	5
GO:0006816	calcium ion transport	20/665	422/18722	0.117598606043009	0.277392060765902	CXCR4/CALM1/ERO1A/LILRA5/TSPO/CLIC2/LGALS3/RHOA/EPB41/SARAF/AHNAK/CALM3/C4orf3/PTK2B/DIAPH1/ANXA2/ORAI3/CXCL12/ATP2C1/PRNP	20
GO:0060828	regulation of canonical Wnt signaling pathway	13/665	253/18722	0.117790783489212	0.277713564488323	APOE/SULF2/DAB2/GNAQ/UBE2B/SMURF2/CCNY/EGR1/EGFR/RBX1/LRRK2/WNK1/TLE3	13
GO:0001541	ovarian follicle development	4/665	53/18722	0.118587392190236	0.278457983493898	VEGFA/CEBPB/ANG/MMP14	4
GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	4/665	53/18722	0.118587392190236	0.278457983493898	CXCL8/ADM/RGS2/ARRDC3	4
GO:0051438	regulation of ubiquitin-protein transferase activity	4/665	53/18722	0.118587392190236	0.278457983493898	PTEN/DTX3L/ARRDC3/SMAD7	4
GO:0060966	regulation of gene silencing by RNA	4/665	53/18722	0.118587392190236	0.278457983493898	ZFP36/HIF1A-AS2/EGFR/ELAVL1	4
GO:0099172	presynapse organization	4/665	53/18722	0.118587392190236	0.278457983493898	IL1RAP/C5AR1/PTEN/SDCBP	4
GO:0000038	very long-chain fatty acid metabolic process	3/665	34/18722	0.118834885913593	0.278457983493898	ACSL1/HSD17B4/HACD4	3
GO:0007616	long-term memory	3/665	34/18722	0.118834885913593	0.278457983493898	APOE/SGK1/PRNP	3
GO:0009303	rRNA transcription	3/665	34/18722	0.118834885913593	0.278457983493898	ANG/NCL/GTF3C6	3
GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	3/665	34/18722	0.118834885913593	0.278457983493898	CALM1/CLIC2/CALM3	3
GO:0016242	negative regulation of macroautophagy	3/665	34/18722	0.118834885913593	0.278457983493898	NUPR1/HMOX1/LRRK2	3
GO:0019320	hexose catabolic process	3/665	34/18722	0.118834885913593	0.278457983493898	HK2/ENO1/GALK1	3
GO:0051085	chaperone cofactor-dependent protein refolding	3/665	34/18722	0.118834885913593	0.278457983493898	CD74/ERO1A/PTGES3	3
GO:0090075	relaxation of muscle	3/665	34/18722	0.118834885913593	0.278457983493898	GSN/RGS2/KCNMA1	3
GO:0015749	monosaccharide transmembrane transport	7/665	116/18722	0.11914844232363	0.279040066685772	SLC2A5/HK2/IRS2/RAP1A/PEA15/SLC2A3/PPBP	7
GO:0009165	nucleotide biosynthetic process	13/665	254/18722	0.120370995453231	0.279040066685772	TREM2/ALDOA/ACSL1/UPP1/PAPSS1/NAMPT/CMPK1/ENO1/PARP9/RRM2B/PAPSS2/GUK1/KMO	13
GO:0001829	trophectodermal cell differentiation	2/665	17/18722	0.120655352778214	0.279040066685772	JUNB/CITED2	2
GO:0009200	deoxyribonucleoside triphosphate metabolic process	2/665	17/18722	0.120655352778214	0.279040066685772	RRM2B/GUK1	2
GO:0009251	glucan catabolic process	2/665	17/18722	0.120655352778214	0.279040066685772	PPP1CB/PPP1R3B	2
GO:0010566	regulation of ketone biosynthetic process	2/665	17/18722	0.120655352778214	0.279040066685772	ADM/EGR1	2
GO:0010612	regulation of cardiac muscle adaptation	2/665	17/18722	0.120655352778214	0.279040066685772	ERRFI1/LMNA	2
GO:0010934	macrophage cytokine production	2/665	17/18722	0.120655352778214	0.279040066685772	CD74/CD36	2
GO:0010935	regulation of macrophage cytokine production	2/665	17/18722	0.120655352778214	0.279040066685772	CD74/CD36	2
GO:0020027	hemoglobin metabolic process	2/665	17/18722	0.120655352778214	0.279040066685772	SLC25A37/KLF4	2
GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway	2/665	17/18722	0.120655352778214	0.279040066685772	VTA1/CHMP5	2
GO:0034349	glial cell apoptotic process	2/665	17/18722	0.120655352778214	0.279040066685772	TREM2/RB1	2
GO:0036035	osteoclast development	2/665	17/18722	0.120655352778214	0.279040066685772	ANXA2/TYROBP	2
GO:0042053	regulation of dopamine metabolic process	2/665	17/18722	0.120655352778214	0.279040066685772	NR4A2/ITGAM	2
GO:0042069	regulation of catecholamine metabolic process	2/665	17/18722	0.120655352778214	0.279040066685772	NR4A2/ITGAM	2
GO:0042448	progesterone metabolic process	2/665	17/18722	0.120655352778214	0.279040066685772	ADM/EGR1	2
GO:0042953	lipoprotein transport	2/665	17/18722	0.120655352778214	0.279040066685772	CD36/MSR1	2
GO:0043117	positive regulation of vascular permeability	2/665	17/18722	0.120655352778214	0.279040066685772	VEGFA/APOE	2
GO:0045198	establishment of epithelial cell apical/basal polarity	2/665	17/18722	0.120655352778214	0.279040066685772	MSN/RHOA	2
GO:0055119	relaxation of cardiac muscle	2/665	17/18722	0.120655352778214	0.279040066685772	GSN/RGS2	2
GO:0061158	3'-UTR-mediated mRNA destabilization	2/665	17/18722	0.120655352778214	0.279040066685772	ZFP36L2/ZFP36	2
GO:0070293	renal absorption	2/665	17/18722	0.120655352778214	0.279040066685772	SGK1/GSN	2
GO:0070875	positive regulation of glycogen metabolic process	2/665	17/18722	0.120655352778214	0.279040066685772	IRS2/IGF2	2
GO:0090036	regulation of protein kinase C signaling	2/665	17/18722	0.120655352778214	0.279040066685772	VEGFA/MYADM	2
GO:0097067	cellular response to thyroid hormone stimulus	2/665	17/18722	0.120655352778214	0.279040066685772	CTSH/KLF9	2
GO:1903242	regulation of cardiac muscle hypertrophy in response to stress	2/665	17/18722	0.120655352778214	0.279040066685772	ERRFI1/LMNA	2
GO:1903540	establishment of protein localization to postsynaptic membrane	2/665	17/18722	0.120655352778214	0.279040066685772	RAB8A/STX3	2
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	2/665	17/18722	0.120655352778214	0.279040066685772	STAT1/PRKX	2
GO:2001257	regulation of cation channel activity	10/665	184/18722	0.120729820176785	0.279082421524939	TREM2/CALM1/CLIC2/KCNE1/IFNGR2/AHNAK/CALM3/KIF5B/PTK2B/EPHB2	10
GO:0051056	regulation of small GTPase mediated signal transduction	15/665	302/18722	0.121047802571686	0.279687391344155	APOE/FBP1/TAGAP/ARHGAP30/SHOC2/RAC1/PPP2CB/SOS2/SQSTM1/DOCK8/PIK3CB/EPHB2/ARHGEF40/SIPA1L1/NRP1	15
GO:0006942	regulation of striated muscle contraction	6/665	95/18722	0.122011952521624	0.281653229926833	CALM1/CLIC2/RGS2/CALM3/NR4A1/SMAD7	6
GO:0030516	regulation of axon extension	6/665	95/18722	0.122011952521624	0.281653229926833	VEGFA/APOE/DPYSL2/FN1/CXCL12/NRP1	6
GO:0046323	glucose import	5/665	74/18722	0.122634255984367	0.282827031202925	HK2/IRS2/RAP1A/PEA15/SLC2A3	5
GO:0070972	protein localization to endoplasmic reticulum	5/665	74/18722	0.122634255984367	0.282827031202925	PPP1R15A/GABARAPL2/SEC61G/LRRK2/INSIG2	5
GO:0014902	myotube differentiation	7/665	117/18722	0.123105804540578	0.283782861116268	CD9/CAPN2/PLEC/MMP14/CD81/PLD3/GPX1	7
GO:0006836	neurotransmitter transport	11/665	208/18722	0.123202218774754	0.283873447988191	SLC6A8/CALM1/SLC1A3/SLC38A2/RAP1A/LRRK2/LIN7C/CALM3/STX3/KMO/NR4A1	11
GO:0010659	cardiac muscle cell apoptotic process	4/665	54/18722	0.124697586939705	0.28678713886642	NUPR1/CAPN2/BNIP3/PTEN	4
GO:0070839	metal ion export	4/665	54/18722	0.124697586939705	0.28678713886642	SLC11A1/CALM1/KCNE1/CALM3	4
GO:1902743	regulation of lamellipodium organization	4/665	54/18722	0.124697586939705	0.28678713886642	CD44/RAC1/PDPN/ABI3	4
GO:2000300	regulation of synaptic vesicle exocytosis	4/665	54/18722	0.124697586939705	0.28678713886642	CALM1/RAP1A/LRRK2/CALM3	4
GO:0030111	regulation of Wnt signaling pathway	16/665	328/18722	0.125436518646055	0.288353144158599	APOE/SULF2/DAB2/GNAQ/UBE2B/TNFAIP3/SMURF2/CCNY/EGR1/EGFR/RBX1/LRRK2/WNK1/TLE3/TLR2/MDFIC	16
GO:1901293	nucleoside phosphate biosynthetic process	13/665	256/18722	0.125628309466193	0.288527124790657	TREM2/ALDOA/ACSL1/UPP1/PAPSS1/NAMPT/CMPK1/ENO1/PARP9/RRM2B/PAPSS2/GUK1/KMO	13
GO:1903522	regulation of blood circulation	13/665	256/18722	0.125628309466193	0.288527124790657	CALM1/ADORA3/ADM/TMIGD3/CLIC2/DOCK4/FLNA/KCNE1/RHOA/RGS2/EGFR/CALM3/SMAD7	13
GO:0090287	regulation of cellular response to growth factor stimulus	15/665	304/18722	0.125862568214471	0.28893162310666	SULF2/DAB2/SKIL/SMURF2/CITED2/PEG10/FBN2/SDCBP/ACVRL1/FBXL15/UBE2D1/PIK3CB/TOB1/CDKN1C/SMAD7	15
GO:0042158	lipoprotein biosynthetic process	6/665	96/18722	0.1264978710222	0.289199433047078	APOE/GLUL/ZDHHC20/GOLGA7/WDR45B/WIPI2	6
GO:1904035	regulation of epithelial cell apoptotic process	6/665	96/18722	0.1264978710222	0.289199433047078	NUPR1/ZFP36/GSN/TNFAIP3/HMOX1/ANGPTL4	6
GO:0006298	mismatch repair	3/665	35/18722	0.126735687158257	0.289199433047078	RPA2/SETD2/XPC	3
GO:0006471	protein ADP-ribosylation	3/665	35/18722	0.126735687158257	0.289199433047078	PARP9/PARP12/TIPARP	3
GO:0006691	leukotriene metabolic process	3/665	35/18722	0.126735687158257	0.289199433047078	ALOX5/ALOX5AP/TLR2	3
GO:0006739	NADP metabolic process	3/665	35/18722	0.126735687158257	0.289199433047078	IDH1/PGAM1/KCNAB2	3
GO:0010765	positive regulation of sodium ion transport	3/665	35/18722	0.126735687158257	0.289199433047078	GLRX/WNK1/KIF5B	3
GO:0018149	peptide cross-linking	3/665	35/18722	0.126735687158257	0.289199433047078	ANXA1/F13A1/FN1	3
GO:0019068	virion assembly	3/665	35/18722	0.126735687158257	0.289199433047078	APOE/VTA1/CHMP5	3
GO:0021955	central nervous system neuron axonogenesis	3/665	35/18722	0.126735687158257	0.289199433047078	NR4A2/PTEN/EPHB2	3
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	3/665	35/18722	0.126735687158257	0.289199433047078	N4BP1/SDCBP/CAMLG	3
GO:0032814	regulation of natural killer cell activation	3/665	35/18722	0.126735687158257	0.289199433047078	HLA-F/HLA-E/TYROBP	3
GO:1903514	release of sequestered calcium ion into cytosol by endoplasmic reticulum	3/665	35/18722	0.126735687158257	0.289199433047078	CALM1/CLIC2/CALM3	3
GO:0031346	positive regulation of cell projection organization	17/665	353/18722	0.127000067219466	0.289355563462332	VEGFA/APOE/SKIL/RAP1A/RAC1/RAPGEF1/RALA/FLNA/RGS2/GRN/CAMK1/PTK2B/FN1/SCARB2/AGRN/CXCL12/NRP1	17
GO:0006633	fatty acid biosynthetic process	9/665	163/18722	0.127036989833965	0.289355563462332	APOC1/CD74/ALOX5/SCD/MIF/ANXA1/PTGES3/INSIG2/HACD4	9
GO:0010976	positive regulation of neuron projection development	9/665	163/18722	0.127036989833965	0.289355563462332	APOE/RAP1A/RAPGEF1/FLNA/RGS2/GRN/CAMK1/PTK2B/SCARB2	9
GO:0071322	cellular response to carbohydrate stimulus	9/665	163/18722	0.127036989833965	0.289355563462332	HLA-DRB1/TREM2/LGALS1/SLC2A5/CLEC7A/DYNLL1/IRS2/RAC1/KIF5B	9
GO:0034219	carbohydrate transmembrane transport	7/665	118/18722	0.127129553472637	0.289433752065508	SLC2A5/HK2/IRS2/RAP1A/PEA15/SLC2A3/PPBP	7
GO:0006094	gluconeogenesis	5/665	75/18722	0.127805194479739	0.290705636871534	PGK1/FBP1/ATF3/TPI1/GPI	5
GO:1903363	negative regulation of cellular protein catabolic process	5/665	75/18722	0.127805194479739	0.290705636871534	N4BP1/GABARAPL2/SDCBP/ANXA2/CAMLG	5
GO:0043331	response to dsRNA	4/665	55/18722	0.130938127478931	0.297423443130843	IFIT1/NFKBIA/IFIH1/RIPK2	4
GO:0046164	alcohol catabolic process	4/665	55/18722	0.130938127478931	0.297423443130843	APOE/TPI1/ALDH2/PTEN	4
GO:0061098	positive regulation of protein tyrosine kinase activity	4/665	55/18722	0.130938127478931	0.297423443130843	LILRA5/NCF1/ABI1/PRNP	4
GO:0014909	smooth muscle cell migration	6/665	97/18722	0.131062833256951	0.29743483163792	DOCK4/RHOA/TRIB1/PLAU/S100A11/NRP1	6
GO:0035335	peptidyl-tyrosine dephosphorylation	6/665	97/18722	0.131062833256951	0.29743483163792	DUSP1/PTP4A2/PTEN/PTPN12/DUSP18/DUSP6	6
GO:0001946	lymphangiogenesis	2/665	18/18722	0.132680520559545	0.297573189161074	PDPN/ACVRL1	2
GO:0002223	stimulatory C-type lectin receptor signaling pathway	2/665	18/18722	0.132680520559545	0.297573189161074	CLEC7A/TYROBP	2
GO:0002544	chronic inflammatory response	2/665	18/18722	0.132680520559545	0.297573189161074	TNFAIP3/S100A8	2
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	2/665	18/18722	0.132680520559545	0.297573189161074	FCGR2B/TREM2	2
GO:0009125	nucleoside monophosphate catabolic process	2/665	18/18722	0.132680520559545	0.297573189161074	TYMP/UPP1	2
GO:0021534	cell proliferation in hindbrain	2/665	18/18722	0.132680520559545	0.297573189161074	ATF5/C5AR1	2
GO:0032785	negative regulation of DNA-templated transcription, elongation	2/665	18/18722	0.132680520559545	0.297573189161074	LARP7/EAPP	2
GO:0034162	toll-like receptor 9 signaling pathway	2/665	18/18722	0.132680520559545	0.297573189161074	RSAD2/GRAMD4	2
GO:0035372	protein localization to microtubule	2/665	18/18722	0.132680520559545	0.297573189161074	MAPRE1/DIAPH1	2
GO:0043116	negative regulation of vascular permeability	2/665	18/18722	0.132680520559545	0.297573189161074	VEGFA/ADM	2
GO:0044247	cellular polysaccharide catabolic process	2/665	18/18722	0.132680520559545	0.297573189161074	PPP1CB/PPP1R3B	2
GO:0044872	lipoprotein localization	2/665	18/18722	0.132680520559545	0.297573189161074	CD36/MSR1	2
GO:0045623	negative regulation of T-helper cell differentiation	2/665	18/18722	0.132680520559545	0.297573189161074	ANXA1/SMAD7	2
GO:0046851	negative regulation of bone remodeling	2/665	18/18722	0.132680520559545	0.297573189161074	HAMP/TNFAIP3	2
GO:0048535	lymph node development	2/665	18/18722	0.132680520559545	0.297573189161074	PDPN/IL7R	2
GO:0055070	copper ion homeostasis	2/665	18/18722	0.132680520559545	0.297573189161074	SCO2/PRNP	2
GO:0060457	negative regulation of digestive system process	2/665	18/18722	0.132680520559545	0.297573189161074	HAMP/WNK1	2
GO:0071071	regulation of phospholipid biosynthetic process	2/665	18/18722	0.132680520559545	0.297573189161074	CAPN2/IDH1	2
GO:0071360	cellular response to exogenous dsRNA	2/665	18/18722	0.132680520559545	0.297573189161074	IFIT1/IFIH1	2
GO:0098877	neurotransmitter receptor transport to plasma membrane	2/665	18/18722	0.132680520559545	0.297573189161074	RAB8A/STX3	2
GO:0150079	negative regulation of neuroinflammatory response	2/665	18/18722	0.132680520559545	0.297573189161074	TREM2/GRN	2
GO:1902683	regulation of receptor localization to synapse	2/665	18/18722	0.132680520559545	0.297573189161074	RAP1A/TYROBP	2
GO:1905820	positive regulation of chromosome separation	2/665	18/18722	0.132680520559545	0.297573189161074	PLSCR1/RB1	2
GO:1990840	response to lectin	2/665	18/18722	0.132680520559545	0.297573189161074	CLEC7A/TYROBP	2
GO:1990858	cellular response to lectin	2/665	18/18722	0.132680520559545	0.297573189161074	CLEC7A/TYROBP	2
GO:2000641	regulation of early endosome to late endosome transport	2/665	18/18722	0.132680520559545	0.297573189161074	DAB2/MSN	2
GO:0043536	positive regulation of blood vessel endothelial cell migration	5/665	76/18722	0.13307411989214	0.298321324250761	VEGFA/HMOX1/ANXA1/MAP3K3/NRP1	5
GO:0046546	development of primary male sexual characteristics	8/665	142/18722	0.13339463745719	0.29890502622283	NUPR1/LHFPL2/YBX3/HSD17B4/CITED2/FLNA/MMP14/RAB13	8
GO:0008207	C21-steroid hormone metabolic process	3/665	36/18722	0.134818470336365	0.301551664073688	ADM/TSPO/EGR1	3
GO:0017004	cytochrome complex assembly	3/665	36/18722	0.134818470336365	0.301551664073688	SCO2/COA6/COX16	3
GO:0090313	regulation of protein targeting to membrane	3/665	36/18722	0.134818470336365	0.301551664073688	ITGAM/KCNE1/PRNP	3
GO:1903539	protein localization to postsynaptic membrane	3/665	36/18722	0.134818470336365	0.301551664073688	RAB8A/RAP1A/STX3	3
GO:0048675	axon extension	7/665	120/18722	0.135373100258524	0.302656009124995	ALCAM/VEGFA/APOE/DPYSL2/FN1/CXCL12/NRP1	7
GO:0043502	regulation of muscle adaptation	6/665	98/18722	0.135705592998079	0.303262948381499	KLF4/ERRFI1/HAMP/RGS2/LMNA/JARID2	6
GO:0048762	mesenchymal cell differentiation	12/665	236/18722	0.136201184090172	0.304233656147484	S100A4/STAT1/DAB2/CITED2/PTEN/PDPN/FLNA/GLIPR2/SDCBP/FN1/SMAD7/NRP1	12
GO:0062013	positive regulation of small molecule metabolic process	8/665	143/18722	0.137208757941944	0.306148816919814	TREM2/CD74/ADM/IRS2/ENO1/ANXA1/PTAFR/IGF2	8
GO:0010658	striated muscle cell apoptotic process	4/665	56/18722	0.137304972417357	0.306148816919814	NUPR1/CAPN2/BNIP3/PTEN	4
GO:0022029	telencephalon cell migration	4/665	56/18722	0.137304972417357	0.306148816919814	CXCR4/RHOA/LRRK2/CXCL12	4
GO:0090175	regulation of establishment of planar polarity	4/665	56/18722	0.137304972417357	0.306148816919814	DAB2/SMURF2/RAC1/RHOA	4
GO:1902904	negative regulation of supramolecular fiber organization	9/665	166/18722	0.137473771139818	0.306387732091882	TREM2/CAPG/APOE/MYADM/GSN/GMFG/MAPRE1/TMSB10/PFDN6	9
GO:0034655	nucleobase-containing compound catabolic process	19/665	407/18722	0.137819643417261	0.30702089994791	VIM/SLC11A1/OAS2/RNASE6/ZFP36L2/TYMP/YBX3/RNASET2/UPP1/SSB/ZFP36/ANG/MYD88/YBX1/HNRNPA0/TOB1/HELZ2/ELAVL1/LSM6	19
GO:0007492	endoderm development	5/665	77/18722	0.138438901605471	0.307986276176898	DUSP1/MMP14/FN1/DUSP2/SETD2	5
GO:0032418	lysosome localization	5/665	77/18722	0.138438901605471	0.307986276176898	CD300A/BLOC1S1/HMOX1/BLOC1S2/KIF5B	5
GO:0055117	regulation of cardiac muscle contraction	5/665	77/18722	0.138438901605471	0.307986276176898	CALM1/CLIC2/RGS2/CALM3/SMAD7	5
GO:0001704	formation of primary germ layer	7/665	121/18722	0.139591242313022	0.310272126250321	DUSP1/KLF4/GPI/MMP14/FN1/DUSP2/SETD2	7
GO:0002455	humoral immune response mediated by circulating immunoglobulin	7/665	121/18722	0.139591242313022	0.310272126250321	FCGR2B/TREM2/SERPING1/C1QB/C1QC/CD81/C1QA	7
GO:0010717	regulation of epithelial to mesenchymal transition	6/665	99/18722	0.14042484963851	0.31198547282226	DAB2/PTEN/PDPN/GLIPR2/SDCBP/SMAD7	6
GO:0042692	muscle cell differentiation	18/665	384/18722	0.141806026847212	0.314913294651762	VEGFA/CD9/CAPN2/ADM/SOD2/HAMP/RGS2/LMNA/YBX1/PLEC/MMP14/CAMK1/CACYBP/IGF2/RB1/CD81/PLD3/GPX1	18
GO:0033363	secretory granule organization	3/665	37/18722	0.143073513470388	0.315797231736609	SRGN/BLOC1S1/BLOC1S2	3
GO:0034260	negative regulation of GTPase activity	3/665	37/18722	0.143073513470388	0.315797231736609	LRRK2/WNK1/CPEB2	3
GO:0062237	protein localization to postsynapse	3/665	37/18722	0.143073513470388	0.315797231736609	RAB8A/RAP1A/STX3	3
GO:0034205	amyloid-beta formation	4/665	57/18722	0.143793980193089	0.315797231736609	APOE/RTN3/APH1A/PRNP	4
GO:0051205	protein insertion into membrane	4/665	57/18722	0.143793980193089	0.315797231736609	EGFR/TIMM8B/CAMLG/TIMM10	4
GO:0043537	negative regulation of blood vessel endothelial cell migration	5/665	78/18722	0.143897334496728	0.315797231736609	APOE/KLF4/CSNK2B/RHOA/ACVRL1	5
GO:0001696	gastric acid secretion	2/665	19/18722	0.144961721607997	0.315797231736609	SGK1/SNX10	2
GO:0006007	glucose catabolic process	2/665	19/18722	0.144961721607997	0.315797231736609	HK2/ENO1	2
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2/665	19/18722	0.144961721607997	0.315797231736609	PLK3/CDKN1A	2
GO:0007039	protein catabolic process in the vacuole	2/665	19/18722	0.144961721607997	0.315797231736609	VPS13A/CD81	2
GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	2/665	19/18722	0.144961721607997	0.315797231736609	GNAQ/AGRN	2
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	2/665	19/18722	0.144961721607997	0.315797231736609	TYMP/UPP1	2
GO:0009301	snRNA transcription	2/665	19/18722	0.144961721607997	0.315797231736609	LARP7/SNAPC2	2
GO:0010544	negative regulation of platelet activation	2/665	19/18722	0.144961721607997	0.315797231736609	CD9/APOE	2
GO:0010738	regulation of protein kinase A signaling	2/665	19/18722	0.144961721607997	0.315797231736609	MIF/LRRK2	2
GO:0010744	positive regulation of macrophage derived foam cell differentiation	2/665	19/18722	0.144961721607997	0.315797231736609	CD36/MSR1	2
GO:0030011	maintenance of cell polarity	2/665	19/18722	0.144961721607997	0.315797231736609	DST/LIN7C	2
GO:0031065	positive regulation of histone deacetylation	2/665	19/18722	0.144961721607997	0.315797231736609	VEGFA/LRRK2	2
GO:0032695	negative regulation of interleukin-12 production	2/665	19/18722	0.144961721607997	0.315797231736609	ACP5/LILRA5	2
GO:0033194	response to hydroperoxide	2/665	19/18722	0.144961721607997	0.315797231736609	CD36/GPX1	2
GO:0035313	wound healing, spreading of epidermal cells	2/665	19/18722	0.144961721607997	0.315797231736609	PTEN/ACVRL1	2
GO:0043031	negative regulation of macrophage activation	2/665	19/18722	0.144961721607997	0.315797231736609	FCGR2B/GRN	2
GO:0043652	engulfment of apoptotic cell	2/665	19/18722	0.144961721607997	0.315797231736609	TREM2/RAC1	2
GO:0044320	cellular response to leptin stimulus	2/665	19/18722	0.144961721607997	0.315797231736609	PTEN/EBI3	2
GO:0045603	positive regulation of endothelial cell differentiation	2/665	19/18722	0.144961721607997	0.315797231736609	BTG1/ACVRL1	2
GO:0046794	transport of virus	2/665	19/18722	0.144961721607997	0.315797231736609	BST2/KPNA3	2
GO:0048245	eosinophil chemotaxis	2/665	19/18722	0.144961721607997	0.315797231736609	LGALS3/CCL13	2
GO:0048490	anterograde synaptic vesicle transport	2/665	19/18722	0.144961721607997	0.315797231736609	BLOC1S1/BLOC1S2	2
GO:0050961	detection of temperature stimulus involved in sensory perception	2/665	19/18722	0.144961721607997	0.315797231736609	CXCR4/CXCL12	2
GO:0051444	negative regulation of ubiquitin-protein transferase activity	2/665	19/18722	0.144961721607997	0.315797231736609	DTX3L/SMAD7	2
GO:0061760	antifungal innate immune response	2/665	19/18722	0.144961721607997	0.315797231736609	CLEC7A/SPI1	2
GO:0062099	negative regulation of programmed necrotic cell death	2/665	19/18722	0.144961721607997	0.315797231736609	NUPR1/YBX3	2
GO:0098780	response to mitochondrial depolarisation	2/665	19/18722	0.144961721607997	0.315797231736609	HK2/SQSTM1	2
GO:0099514	synaptic vesicle cytoskeletal transport	2/665	19/18722	0.144961721607997	0.315797231736609	BLOC1S1/BLOC1S2	2
GO:0099517	synaptic vesicle transport along microtubule	2/665	19/18722	0.144961721607997	0.315797231736609	BLOC1S1/BLOC1S2	2
GO:0140131	positive regulation of lymphocyte chemotaxis	2/665	19/18722	0.144961721607997	0.315797231736609	WNK1/PTK2B	2
GO:1900221	regulation of amyloid-beta clearance	2/665	19/18722	0.144961721607997	0.315797231736609	TREM2/APOE	2
GO:1903975	regulation of glial cell migration	2/665	19/18722	0.144961721607997	0.315797231736609	TREM2/GPR183	2
GO:2000319	regulation of T-helper 17 cell differentiation	2/665	19/18722	0.144961721607997	0.315797231736609	NFKBIZ/SMAD7	2
GO:2000369	regulation of clathrin-dependent endocytosis	2/665	19/18722	0.144961721607997	0.315797231736609	DAB2/PIK3CB	2
GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	2/665	19/18722	0.144961721607997	0.315797231736609	HLA-A/HLA-E	2
GO:0007269	neurotransmitter secretion	8/665	145/18722	0.144999855698781	0.315797231736609	CALM1/RAP1A/LRRK2/LIN7C/CALM3/STX3/KMO/NR4A1	8
GO:0051961	negative regulation of nervous system development	8/665	145/18722	0.144999855698781	0.315797231736609	TREM2/B2M/YWHAH/TSPO/PTEN/EPHB2/TLR2/NRP1	8
GO:0099643	signal release from synapse	8/665	145/18722	0.144999855698781	0.315797231736609	CALM1/RAP1A/LRRK2/LIN7C/CALM3/STX3/KMO/NR4A1	8
GO:0006641	triglyceride metabolic process	6/665	100/18722	0.145219250466691	0.315998106313247	APOE/APOC1/ACSL1/INSIG2/ABHD5/GPX1	6
GO:0060840	artery development	6/665	100/18722	0.145219250466691	0.315998106313247	VEGFA/APOE/CITED2/ACVRL1/SMAD7/NRP1	6
GO:0072503	cellular divalent inorganic cation homeostasis	22/665	486/18722	0.146700544944553	0.319081710448328	SLC11A1/CXCR4/FPR3/APOE/CALM1/ERO1A/ADM/C5AR1/CD36/CLIC2/MT1X/BNIP3/CALM3/S100A8/PTK2B/DIAPH1/CCL13/GRINA/HEXB/CXCL12/ATP2C1/PRNP	22
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	5/665	79/18722	0.149447143764457	0.324487682179708	TREM2/NCF1/HCLS1/FN1/HAX1	5
GO:0032272	negative regulation of protein polymerization	5/665	79/18722	0.149447143764457	0.324487682179708	CAPG/MYADM/GSN/MAPRE1/TMSB10	5
GO:0050772	positive regulation of axonogenesis	5/665	79/18722	0.149447143764457	0.324487682179708	VEGFA/SKIL/FN1/CXCL12/NRP1	5
GO:0051279	regulation of release of sequestered calcium ion into cytosol	5/665	79/18722	0.149447143764457	0.324487682179708	CALM1/CLIC2/CALM3/PTK2B/DIAPH1	5
GO:0006476	protein deacetylation	6/665	101/18722	0.150087392962359	0.325593340472686	VEGFA/FLNA/LRRK2/MORF4L1/PHB/PER1	6
GO:0006576	cellular biogenic amine metabolic process	6/665	101/18722	0.150087392962359	0.325593340472686	IL4I1/NR4A2/LY6E/ITGAM/OAZ1/KMO	6
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	4/665	58/18722	0.150400920764841	0.326131141449066	NUPR1/SKIL/MCL1/S100A8	4
GO:0006813	potassium ion transport	12/665	241/18722	0.151272687918413	0.327068075977921	TREM2/SLC1A3/KCNQ3/PTEN/FLNA/KCNE1/WNK1/KIF5B/KCNAB2/PTK2B/KCNMA1/PRNP	12
GO:0023061	signal release	21/665	463/18722	0.1513212360962	0.327068075977921	HLA-DRB1/ALOX5/CALM1/GLUL/ADM/DYNLL1/IRS2/RAP1A/CGA/RAC1/ANXA1/EGFR/LRRK2/LIN7C/CALM3/KIF5B/STX3/KMO/NR4A1/SLC16A10/CXCL12	21
GO:0007007	inner mitochondrial membrane organization	3/665	38/18722	0.15149108871251	0.327068075977921	TIMM8B/TIMM10/CHCHD3	3
GO:0035886	vascular associated smooth muscle cell differentiation	3/665	38/18722	0.15149108871251	0.327068075977921	VEGFA/ADM/SOD2	3
GO:0072524	pyridine-containing compound metabolic process	3/665	38/18722	0.15149108871251	0.327068075977921	NAMPT/PARP9/KMO	3
GO:0098926	postsynaptic signal transduction	3/665	38/18722	0.15149108871251	0.327068075977921	GNAQ/LY6E/AGRN	3
GO:1901031	regulation of response to reactive oxygen species	3/665	38/18722	0.15149108871251	0.327068075977921	CD36/LRRK2/TXN	3
GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	3/665	38/18722	0.15149108871251	0.327068075977921	BNIP3L/BNIP3/BLOC1S2	3
GO:1903580	positive regulation of ATP metabolic process	3/665	38/18722	0.15149108871251	0.327068075977921	NUPR1/TREM2/ENO1	3
GO:1903725	regulation of phospholipid metabolic process	3/665	38/18722	0.15149108871251	0.327068075977921	CAPN2/APOC1/IDH1	3
GO:0002790	peptide secretion	12/665	242/18722	0.154387863909991	0.333177457070193	HLA-DRB1/CD74/ALOX5/GLUL/DYNLL1/IRS2/RAC1/ANXA1/EGFR/S100A8/KIF5B/SLC16A10	12
GO:0010522	regulation of calcium ion transport into cytosol	6/665	102/18722	0.155027827108297	0.334268243266046	CALM1/CLIC2/CALM3/PTK2B/DIAPH1/PRNP	6
GO:0062014	negative regulation of small molecule metabolic process	6/665	102/18722	0.155027827108297	0.334268243266046	NUPR1/APOE/DDIT4/APOC1/FBP1/INSIG2	6
GO:0006631	fatty acid metabolic process	18/665	390/18722	0.156197066024041	0.335881709565107	APOC1/CD74/ALOX5/SCD/ACSL1/HSD17B4/MIF/CD36/IRS2/ALOX5AP/ANXA1/PTGES3/INSIG2/HACD4/CYP1B1/ALDH3A2/ABHD5/GPX1	18
GO:0044839	cell cycle G2/M phase transition	8/665	148/18722	0.157083766500228	0.335881709565107	ATF5/CALM1/CCNY/CALM3/PLK3/CDKN1A/FBXL15/FOXN3	8
GO:0019369	arachidonic acid metabolic process	4/665	59/18722	0.157121486915104	0.335881709565107	ALOX5/PTGES3/CYP1B1/GPX1	4
GO:0021885	forebrain cell migration	4/665	59/18722	0.157121486915104	0.335881709565107	CXCR4/RHOA/LRRK2/CXCL12	4
GO:0035306	positive regulation of dephosphorylation	4/665	59/18722	0.157121486915104	0.335881709565107	CD300A/CALM1/PPP1R15A/CALM3	4
GO:0046324	regulation of glucose import	4/665	59/18722	0.157121486915104	0.335881709565107	HK2/IRS2/RAP1A/PEA15	4
GO:0090303	positive regulation of wound healing	4/665	59/18722	0.157121486915104	0.335881709565107	CXCR4/CLEC7A/CD36/ANXA1	4
GO:0000272	polysaccharide catabolic process	2/665	20/18722	0.157465670681429	0.335881709565107	PPP1CB/PPP1R3B	2
GO:0002115	store-operated calcium entry	2/665	20/18722	0.157465670681429	0.335881709565107	SARAF/ORAI3	2
GO:0006590	thyroid hormone generation	2/665	20/18722	0.157465670681429	0.335881709565107	CGA/SLC16A10	2
GO:0010893	positive regulation of steroid biosynthetic process	2/665	20/18722	0.157465670681429	0.335881709565107	ADM/CGA	2
GO:0032332	positive regulation of chondrocyte differentiation	2/665	20/18722	0.157465670681429	0.335881709565107	ACVRL1/SMAD7	2
GO:0034104	negative regulation of tissue remodeling	2/665	20/18722	0.157465670681429	0.335881709565107	HAMP/TNFAIP3	2
GO:0039535	regulation of RIG-I signaling pathway	2/665	20/18722	0.157465670681429	0.335881709565107	DDX60/OASL	2
GO:0043555	regulation of translation in response to stress	2/665	20/18722	0.157465670681429	0.335881709565107	EIF2AK2/PPP1R15A	2
GO:0045063	T-helper 1 cell differentiation	2/665	20/18722	0.157465670681429	0.335881709565107	ANXA1/RIPK2	2
GO:0060252	positive regulation of glial cell proliferation	2/665	20/18722	0.157465670681429	0.335881709565107	TSPO/EGFR	2
GO:0071731	response to nitric oxide	2/665	20/18722	0.157465670681429	0.335881709565107	EGLN1/TXN	2
GO:0090201	negative regulation of release of cytochrome c from mitochondria	2/665	20/18722	0.157465670681429	0.335881709565107	LMNA/GPX1	2
GO:1901386	negative regulation of voltage-gated calcium channel activity	2/665	20/18722	0.157465670681429	0.335881709565107	CALM1/CALM3	2
GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	2/665	20/18722	0.157465670681429	0.335881709565107	SOD2/GPX1	2
GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	2/665	20/18722	0.157465670681429	0.335881709565107	LRRK2/GRINA	2
GO:1903206	negative regulation of hydrogen peroxide-induced cell death	2/665	20/18722	0.157465670681429	0.335881709565107	LRRK2/TXN	2
GO:1904263	positive regulation of TORC1 signaling	2/665	20/18722	0.157465670681429	0.335881709565107	LAMTOR5/RRAGD	2
GO:2000010	positive regulation of protein localization to cell surface	2/665	20/18722	0.157465670681429	0.335881709565107	STX3/TYROBP	2
GO:0030004	cellular monovalent inorganic cation homeostasis	6/665	103/18722	0.160039057713295	0.340396068641405	SLC11A1/SLC1A3/RAB20/LRRK2/GRN/KCNMA1	6
GO:0010463	mesenchymal cell proliferation	3/665	39/18722	0.160061491431582	0.340396068641405	STAT1/IRS2/LMNA	3
GO:0032506	cytokinetic process	3/665	39/18722	0.160061491431582	0.340396068641405	RHOA/PLEC/CHMP5	3
GO:0034314	Arp2/3 complex-mediated actin nucleation	3/665	39/18722	0.160061491431582	0.340396068641405	GMFG/ARPC4/IQGAP2	3
GO:0043267	negative regulation of potassium ion transport	3/665	39/18722	0.160061491431582	0.340396068641405	PTEN/KCNE1/PTK2B	3
GO:0045923	positive regulation of fatty acid metabolic process	3/665	39/18722	0.160061491431582	0.340396068641405	CD74/IRS2/ANXA1	3
GO:0051084	'de novo' posttranslational protein folding	3/665	39/18722	0.160061491431582	0.340396068641405	CD74/ERO1A/PTGES3	3
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	5/665	81/18722	0.160811472525591	0.341597154652824	SKIL/SMURF2/PEG10/FBN2/SMAD7	5
GO:2001021	negative regulation of response to DNA damage stimulus	5/665	81/18722	0.160811472525591	0.341597154652824	CD74/MIF/CD44/ZNF385A/CXCL12	5
GO:0001763	morphogenesis of a branching structure	10/665	196/18722	0.16083246315646	0.341597154652824	VEGFA/CTSH/ADM/ST14/GRB2/SOCS3/LRRK2/MMP14/SETD2/NRP1	10
GO:0016311	dephosphorylation	19/665	417/18722	0.161072267643947	0.341960346087321	CD300A/DUSP1/NT5C3A/CALM1/FBP1/ACP5/CSNK2B/PPP1R15A/LGALS3/PPP1CB/PPP1R3B/PTP4A2/PTEN/PPP2CB/PTPN12/LRRK2/CALM3/DUSP18/DUSP6	19
GO:0032368	regulation of lipid transport	8/665	149/18722	0.161214853186586	0.341970900698819	TREM2/APOE/APOC1/NFKBIA/ACSL1/TSPO/IRS2/ANXA2	8
GO:1905039	carboxylic acid transmembrane transport	8/665	149/18722	0.161214853186586	0.341970900698819	SLC16A3/SLC1A3/ACSL1/CD36/IRS2/SLC38A2/RGS2/SLC16A10	8
GO:0001822	kidney development	14/665	293/18722	0.161460053804311	0.342344909303509	VEGFA/CTSH/SULF2/STAT1/PRKX/RRM2B/RHOA/EGR1/LRRK2/APH1A/GCNT1/TIPARP/SMAD7/NRP1	14
GO:0000910	cytokinesis	9/665	173/18722	0.163468276367915	0.346307473805855	CALM1/RHOA/RHOB/PLEC/RHOC/CALM3/PLK3/CHMP5/SETD2	9
GO:0006694	steroid biosynthetic process	9/665	173/18722	0.163468276367915	0.346307473805855	APOE/ADM/TSPO/HSD17B11/CGA/EGR1/OSBPL1A/INSIG2/HSD17B1	9
GO:0017148	negative regulation of translation	12/665	245/18722	0.16393040508407	0.347138522909173	ZFP36L2/EIF2AK2/ZFP36/ANG/GAPDH/EIF4EBP1/RGS2/YBX1/NCL/EIF4E/TOB1/CPEB2	12
GO:0006892	post-Golgi vesicle-mediated transport	6/665	104/18722	0.165119546741713	0.349358938827721	VAMP5/GOLGA7/KRT18/RAB31/VPS13A/ATP2C1	6
GO:0060419	heart growth	6/665	104/18722	0.165119546741713	0.349358938827721	HAMP/CITED2/PTEN/RGS2/JARID2/DUSP6	6
GO:0008202	steroid metabolic process	15/665	319/18722	0.165393644472508	0.349646684392481	APOE/APOC1/YWHAH/ADM/HSD17B4/TSPO/HSD17B11/CGA/EGR1/OSBPL1A/SOAT1/INSIG2/CYP1B1/TIPARP/HSD17B1	15
GO:1903825	organic acid transmembrane transport	8/665	150/18722	0.165396248492298	0.349646684392481	SLC16A3/SLC1A3/ACSL1/CD36/IRS2/SLC38A2/RGS2/SLC16A10	8
GO:0030048	actin filament-based movement	7/665	127/18722	0.166191198483529	0.351177830128887	MYO1G/GSN/PDPN/FLNA/KCNE1/WIPF1/MYL6	7
GO:0007032	endosome organization	5/665	82/18722	0.16662113689055	0.351637813310417	SNX10/SQSTM1/SCARB2/VTA1/CHMP5	5
GO:0009205	purine ribonucleoside triphosphate metabolic process	5/665	82/18722	0.16662113689055	0.351637813310417	TREM2/ALDOA/ENO1/RHOA/LRRK2	5
GO:0016575	histone deacetylation	5/665	82/18722	0.16662113689055	0.351637813310417	VEGFA/LRRK2/MORF4L1/PHB/PER1	5
GO:0007584	response to nutrient	9/665	174/18722	0.167361878279364	0.353051160886434	LDHA/STAT1/ACSL1/SOD2/TSPO/HAMP/PTEN/HMOX1/EGFR	9
GO:0002714	positive regulation of B cell mediated immunity	3/665	40/18722	0.168775066669971	0.354527506910293	TREM2/HLA-E/TFRC	3
GO:0002891	positive regulation of immunoglobulin mediated immune response	3/665	40/18722	0.168775066669971	0.354527506910293	TREM2/HLA-E/TFRC	3
GO:0009394	2'-deoxyribonucleotide metabolic process	3/665	40/18722	0.168775066669971	0.354527506910293	TYMP/UPP1/GUK1	3
GO:0010543	regulation of platelet activation	3/665	40/18722	0.168775066669971	0.354527506910293	CD9/APOE/PDPN	3
GO:0030501	positive regulation of bone mineralization	3/665	40/18722	0.168775066669971	0.354527506910293	ISG15/ALOX5/FBN2	3
GO:0030866	cortical actin cytoskeleton organization	3/665	40/18722	0.168775066669971	0.354527506910293	PLEC/EPB41/RAB13	3
GO:0045022	early endosome to late endosome transport	3/665	40/18722	0.168775066669971	0.354527506910293	DAB2/MSN/FLNA	3
GO:0046365	monosaccharide catabolic process	3/665	40/18722	0.168775066669971	0.354527506910293	HK2/ENO1/GALK1	3
GO:0071526	semaphorin-plexin signaling pathway	3/665	40/18722	0.168775066669971	0.354527506910293	RAC1/FLNA/NRP1	3
GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	3/665	40/18722	0.168775066669971	0.354527506910293	BNIP3L/BNIP3/BLOC1S2	3
GO:0006123	mitochondrial electron transport, cytochrome c to oxygen	2/665	21/18722	0.170161117683193	0.354591511482376	CYCS/COX5B	2
GO:0006244	pyrimidine nucleotide catabolic process	2/665	21/18722	0.170161117683193	0.354591511482376	TYMP/UPP1	2
GO:0007617	mating behavior	2/665	21/18722	0.170161117683193	0.354591511482376	PTEN/HEXB	2
GO:0008090	retrograde axonal transport	2/665	21/18722	0.170161117683193	0.354591511482376	DST/KIF5B	2
GO:0010988	regulation of low-density lipoprotein particle clearance	2/665	21/18722	0.170161117683193	0.354591511482376	TREM2/ANXA2	2
GO:0019370	leukotriene biosynthetic process	2/665	21/18722	0.170161117683193	0.354591511482376	ALOX5/ALOX5AP	2
GO:0022010	central nervous system myelination	2/665	21/18722	0.170161117683193	0.354591511482376	PTEN/TLR2	2
GO:0032288	myelin assembly	2/665	21/18722	0.170161117683193	0.354591511482376	CD9/TLR2	2
GO:0032291	axon ensheathment in central nervous system	2/665	21/18722	0.170161117683193	0.354591511482376	PTEN/TLR2	2
GO:0034471	ncRNA 5'-end processing	2/665	21/18722	0.170161117683193	0.354591511482376	SSB/RPP30	2
GO:0045717	negative regulation of fatty acid biosynthetic process	2/665	21/18722	0.170161117683193	0.354591511482376	APOC1/INSIG2	2
GO:0046885	regulation of hormone biosynthetic process	2/665	21/18722	0.170161117683193	0.354591511482376	ADM/EGR1	2
GO:0048714	positive regulation of oligodendrocyte differentiation	2/665	21/18722	0.170161117683193	0.354591511482376	CXCR4/TLR2	2
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	2/665	21/18722	0.170161117683193	0.354591511482376	CD74/CD36	2
GO:0072111	cell proliferation involved in kidney development	2/665	21/18722	0.170161117683193	0.354591511482376	STAT1/EGR1	2
GO:0090141	positive regulation of mitochondrial fission	2/665	21/18722	0.170161117683193	0.354591511482376	BNIP3/RALA	2
GO:1903427	negative regulation of reactive oxygen species biosynthetic process	2/665	21/18722	0.170161117683193	0.354591511482376	PAGE4/RHOA	2
GO:1903429	regulation of cell maturation	2/665	21/18722	0.170161117683193	0.354591511482376	CLEC7A/LRRK2	2
GO:2000774	positive regulation of cellular senescence	2/665	21/18722	0.170161117683193	0.354591511482376	B2M/ABI3	2
GO:0032231	regulation of actin filament bundle assembly	6/665	105/18722	0.170267715645263	0.354664939965196	S100A10/RAC1/FLNA/RHOA/RHOC/NRP1	6
GO:0006639	acylglycerol metabolic process	7/665	128/18722	0.170830296704631	0.355208344946546	APOE/APOC1/ACSL1/ANG/INSIG2/ABHD5/GPX1	7
GO:0030199	collagen fibril organization	4/665	61/18722	0.170885946230823	0.355208344946546	P4HA1/ANXA2/RB1/CYP1B1	4
GO:0043954	cellular component maintenance	4/665	61/18722	0.170885946230823	0.355208344946546	FCGR2B/TREM2/APOE/PRNP	4
GO:0050994	regulation of lipid catabolic process	4/665	61/18722	0.170885946230823	0.355208344946546	APOC1/IRS2/IDH1/ABHD5	4
GO:0060998	regulation of dendritic spine development	4/665	61/18722	0.170885946230823	0.355208344946546	APOE/TANC2/PTEN/CAMK1	4
GO:0030509	BMP signaling pathway	8/665	152/18722	0.173906797247816	0.361336447458882	SKIL/SMURF2/EGR1/ACVRL1/FBXL15/UBE2D1/TOB1/SMAD7	8
GO:0030038	contractile actin filament bundle assembly	6/665	106/18722	0.175481947692771	0.363786810606083	S100A10/RAC1/RHOA/RHOC/PTK2B/NRP1	6
GO:0043149	stress fiber assembly	6/665	106/18722	0.175481947692771	0.363786810606083	S100A10/RAC1/RHOA/RHOC/PTK2B/NRP1	6
GO:0090263	positive regulation of canonical Wnt signaling pathway	6/665	106/18722	0.175481947692771	0.363786810606083	SULF2/UBE2B/SMURF2/EGFR/LRRK2/WNK1	6
GO:0002791	regulation of peptide secretion	10/665	200/18722	0.175498283840078	0.363786810606083	HLA-DRB1/CD74/ALOX5/GLUL/DYNLL1/IRS2/RAC1/EGFR/S100A8/KIF5B	10
GO:0006638	neutral lipid metabolic process	7/665	129/18722	0.175525306203901	0.363786810606083	APOE/APOC1/ACSL1/ANG/INSIG2/ABHD5/GPX1	7
GO:0007093	mitotic cell cycle checkpoint signaling	7/665	129/18722	0.175525306203901	0.363786810606083	DUSP1/RPS27L/RPA2/PLK3/CDKN1A/FOXN3/XPC	7
GO:0001953	negative regulation of cell-matrix adhesion	3/665	41/18722	0.177622233140131	0.367366832586955	PTEN/MMP14/ACVRL1	3
GO:0070296	sarcoplasmic reticulum calcium ion transport	3/665	41/18722	0.177622233140131	0.367366832586955	CALM1/CLIC2/CALM3	3
GO:0071470	cellular response to osmotic stress	3/665	41/18722	0.177622233140131	0.367366832586955	YBX3/ERRFI1/TSPO	3
GO:1901385	regulation of voltage-gated calcium channel activity	3/665	41/18722	0.177622233140131	0.367366832586955	CALM1/AHNAK/CALM3	3
GO:2000008	regulation of protein localization to cell surface	3/665	41/18722	0.177622233140131	0.367366832586955	KCNAB2/STX3/TYROBP	3
GO:0009116	nucleoside metabolic process	4/665	62/18722	0.177920935208616	0.367373098457342	NT5C3A/TYMP/UPP1/ERH	4
GO:0045576	mast cell activation	4/665	62/18722	0.177920935208616	0.367373098457342	CD300A/NDRG1/PLSCR1/HMOX1	4
GO:0048488	synaptic vesicle endocytosis	4/665	62/18722	0.177920935208616	0.367373098457342	CALM1/FCHO2/LRRK2/CALM3	4
GO:0140238	presynaptic endocytosis	4/665	62/18722	0.177920935208616	0.367373098457342	CALM1/FCHO2/LRRK2/CALM3	4
GO:0071331	cellular response to hexose stimulus	8/665	153/18722	0.178234309731689	0.367714619911371	HLA-DRB1/TREM2/LGALS1/SLC2A5/DYNLL1/IRS2/RAC1/KIF5B	8
GO:0120254	olefinic compound metabolic process	8/665	153/18722	0.178234309731689	0.367714619911371	ALOX5/ADM/EGR1/DHRS3/PTGES3/CYP1B1/HSD17B1/GPX1	8
GO:0032370	positive regulation of lipid transport	5/665	84/18722	0.178482939492984	0.367922110858619	TREM2/APOE/NFKBIA/ACSL1/ANXA2	5
GO:0045445	myoblast differentiation	5/665	84/18722	0.178482939492984	0.367922110858619	LGALS1/BTG1/PLEC/RB1/IFRD1	5
GO:0006403	RNA localization	10/665	201/18722	0.179259929637426	0.369299984975743	MX2/SSB/ZFP36/NUP58/NOP10/YBX1/HNRNPA1/MRPL18/ZNF385A/SETD2	10
GO:0098739	import across plasma membrane	9/665	177/18722	0.179299972584803	0.369299984975743	SLC2A5/SLC1A3/ACSL1/CD36/IRS2/SLC2A3/RGS2/WNK1/PRNP	9
GO:0006956	complement activation	7/665	130/18722	0.180275080641546	0.371154577791419	TREM2/SERPING1/CFD/C1QB/C1QC/PHB/C1QA	7
GO:0006275	regulation of DNA replication	6/665	107/18722	0.180760590293925	0.372000055387498	JUN/RAC1/EGFR/ACVRL1/CACYBP/S100A11	6
GO:0030856	regulation of epithelial cell differentiation	8/665	154/18722	0.182608850505014	0.372259172114337	VEGFA/STAT1/BTG1/CEBPB/ERRFI1/ZFP36/PRKX/ACVRL1	8
GO:0050770	regulation of axonogenesis	8/665	154/18722	0.182608850505014	0.372259172114337	VEGFA/SKIL/PTEN/EPHB2/FN1/CXCL12/SIPA1L1/NRP1	8
GO:0071326	cellular response to monosaccharide stimulus	8/665	154/18722	0.182608850505014	0.372259172114337	HLA-DRB1/TREM2/LGALS1/SLC2A5/DYNLL1/IRS2/RAC1/KIF5B	8
GO:0060562	epithelial tube morphogenesis	15/665	325/18722	0.182826517300698	0.372259172114337	CXCR4/VEGFA/CTSH/ADM/CSNK2B/ST14/CITED2/PRKX/RALA/RHOA/RHOB/MMP14/ACVRL1/SETD2/NRP1	15
GO:0002053	positive regulation of mesenchymal cell proliferation	2/665	22/18722	0.183018745439393	0.372259172114337	STAT1/IRS2	2
GO:0002220	innate immune response activating cell surface receptor signaling pathway	2/665	22/18722	0.183018745439393	0.372259172114337	CLEC7A/TYROBP	2
GO:0002320	lymphoid progenitor cell differentiation	2/665	22/18722	0.183018745439393	0.372259172114337	SPI1/SOS2	2
GO:0007413	axonal fasciculation	2/665	22/18722	0.183018745439393	0.372259172114337	EPHB2/NRP1	2
GO:0009220	pyrimidine ribonucleotide biosynthetic process	2/665	22/18722	0.183018745439393	0.372259172114337	UPP1/CMPK1	2
GO:0010310	regulation of hydrogen peroxide metabolic process	2/665	22/18722	0.183018745439393	0.372259172114337	SOD2/RAC1	2
GO:0019400	alditol metabolic process	2/665	22/18722	0.183018745439393	0.372259172114337	TPI1/GALK1	2
GO:0032693	negative regulation of interleukin-10 production	2/665	22/18722	0.183018745439393	0.372259172114337	FCGR2B/TYROBP	2
GO:0032700	negative regulation of interleukin-17 production	2/665	22/18722	0.183018745439393	0.372259172114337	IL27RA/PRNP	2
GO:0032891	negative regulation of organic acid transport	2/665	22/18722	0.183018745439393	0.372259172114337	IRS2/RGS2	2
GO:0033617	mitochondrial cytochrome c oxidase assembly	2/665	22/18722	0.183018745439393	0.372259172114337	SCO2/COX16	2
GO:0035089	establishment of apical/basal cell polarity	2/665	22/18722	0.183018745439393	0.372259172114337	MSN/RHOA	2
GO:0035561	regulation of chromatin binding	2/665	22/18722	0.183018745439393	0.372259172114337	DTX3L/PARP9	2
GO:0042430	indole-containing compound metabolic process	2/665	22/18722	0.183018745439393	0.372259172114337	IL4I1/KMO	2
GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	2/665	22/18722	0.183018745439393	0.372259172114337	ANXA1/SMAD7	2
GO:0048169	regulation of long-term neuronal synaptic plasticity	2/665	22/18722	0.183018745439393	0.372259172114337	RAB8A/EPHB2	2
GO:0051220	cytoplasmic sequestering of protein	2/665	22/18722	0.183018745439393	0.372259172114337	NFKBIA/FLNA	2
GO:0060563	neuroepithelial cell differentiation	2/665	22/18722	0.183018745439393	0.372259172114337	CEBPB/FAM20C	2
GO:0060965	negative regulation of gene silencing by miRNA	2/665	22/18722	0.183018745439393	0.372259172114337	HIF1A-AS2/ELAVL1	2
GO:0071359	cellular response to dsRNA	2/665	22/18722	0.183018745439393	0.372259172114337	IFIT1/IFIH1	2
GO:0090280	positive regulation of calcium ion import	2/665	22/18722	0.183018745439393	0.372259172114337	LGALS3/CXCL12	2
GO:0106030	neuron projection fasciculation	2/665	22/18722	0.183018745439393	0.372259172114337	EPHB2/NRP1	2
GO:1901032	negative regulation of response to reactive oxygen species	2/665	22/18722	0.183018745439393	0.372259172114337	LRRK2/TXN	2
GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	2/665	22/18722	0.183018745439393	0.372259172114337	VEGFA/HMOX1	2
GO:0090087	regulation of peptide transport	10/665	202/18722	0.18305863514033	0.372259172114337	HLA-DRB1/CD74/ALOX5/GLUL/DYNLL1/IRS2/RAC1/EGFR/S100A8/KIF5B	10
GO:0055013	cardiac muscle cell development	5/665	85/18722	0.184529931090298	0.37494429988503	VEGFA/HAMP/RGS2/LMNA/PLEC	5
GO:2000779	regulation of double-strand break repair	5/665	85/18722	0.184529931090298	0.37494429988503	TERF2IP/DTX3L/PARP9/RPA2/SETD2	5
GO:0022617	extracellular matrix disassembly	4/665	63/18722	0.185051761166343	0.37544484953152	ADAM8/MMP19/PDPN/MMP14	4
GO:0046902	regulation of mitochondrial membrane permeability	4/665	63/18722	0.185051761166343	0.37544484953152	HK2/BNIP3L/BNIP3/BLOC1S2	4
GO:0019827	stem cell population maintenance	7/665	131/18722	0.185078446952158	0.37544484953152	ZFP36L2/KLF4/KLF10/SPI1/EIF4E/ELAVL1/ZC3H13	7
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	7/665	131/18722	0.185078446952158	0.37544484953152	SKIL/SMURF2/PEG10/FBN2/UBE2D1/TOB1/SMAD7	7
GO:0007520	myoblast fusion	3/665	42/18722	0.186593504921358	0.376979560755751	CD9/CAPN2/CD81	3
GO:0010677	negative regulation of cellular carbohydrate metabolic process	3/665	42/18722	0.186593504921358	0.376979560755751	NUPR1/DDIT4/FBP1	3
GO:0014003	oligodendrocyte development	3/665	42/18722	0.186593504921358	0.376979560755751	CD9/PTEN/TLR2	3
GO:0019692	deoxyribose phosphate metabolic process	3/665	42/18722	0.186593504921358	0.376979560755751	TYMP/UPP1/GUK1	3
GO:0032965	regulation of collagen biosynthetic process	3/665	42/18722	0.186593504921358	0.376979560755751	VIM/ERRFI1/RAP1A	3
GO:0033003	regulation of mast cell activation	3/665	42/18722	0.186593504921358	0.376979560755751	CD300A/PLSCR1/HMOX1	3
GO:0035019	somatic stem cell population maintenance	3/665	42/18722	0.186593504921358	0.376979560755751	ZFP36L2/KLF10/SPI1	3
GO:0042168	heme metabolic process	3/665	42/18722	0.186593504921358	0.376979560755751	TSPO/HMOX1/UROD	3
GO:0051452	intracellular pH reduction	3/665	42/18722	0.186593504921358	0.376979560755751	SLC11A1/RAB20/GRN	3
GO:0051602	response to electrical stimulus	3/665	42/18722	0.186593504921358	0.376979560755751	SOD2/PTEN/NR4A1	3
GO:0060541	respiratory system development	10/665	203/18722	0.186893867883952	0.377432963585225	VEGFA/CTSH/ERRFI1/PDPN/EIF4EBP1/KLF2/PTGES3/EGFR/MMP14/EIF4E	10
GO:0072001	renal system development	14/665	302/18722	0.188776995896138	0.38108110057019	VEGFA/CTSH/SULF2/STAT1/PRKX/RRM2B/RHOA/EGR1/LRRK2/APH1A/GCNT1/TIPARP/SMAD7/NRP1	14
GO:0022406	membrane docking	5/665	86/18722	0.190650819827702	0.384551369538831	CALM1/RAB8A/MSN/STX3/RAB13	5
GO:0046928	regulation of neurotransmitter secretion	5/665	86/18722	0.190650819827702	0.384551369538831	CALM1/RAP1A/LRRK2/CALM3/KMO	5
GO:0001764	neuron migration	8/665	156/18722	0.191495501108043	0.385941865574604	CXCR4/VEGFA/DDIT4/NR4A2/RAC1/FLNA/CXCL12/NRP1	8
GO:0035051	cardiocyte differentiation	8/665	156/18722	0.191495501108043	0.385941865574604	VEGFA/HAMP/CITED2/RGS2/LMNA/EGFR/PLEC/CACYBP	8
GO:0010721	negative regulation of cell development	9/665	180/18722	0.191610386631704	0.386016871325322	TREM2/VEGFA/B2M/YWHAH/TSPO/PTEN/GBP1/EPHB2/NRP1	9
GO:0015849	organic acid transport	14/665	303/18722	0.191942037750477	0.386528333719559	SLC11A1/PLIN2/APOE/SLC16A3/SLC1A3/ACSL1/CD36/IRS2/SLC38A2/ANXA1/RGS2/ABCC3/KMO/SLC16A10	14
GO:0030837	negative regulation of actin filament polymerization	4/665	64/18722	0.192273886460653	0.386570071079873	CAPG/MYADM/GSN/TMSB10	4
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	4/665	64/18722	0.192273886460653	0.386570071079873	HLA-DRB1/DYNLL1/RAC1/KIF5B	4
GO:0098930	axonal transport	4/665	64/18722	0.192273886460653	0.386570071079873	BLOC1S1/BLOC1S2/DST/KIF5B	4
GO:1903051	negative regulation of proteolysis involved in cellular protein catabolic process	4/665	64/18722	0.192273886460653	0.386570071079873	N4BP1/GABARAPL2/SDCBP/CAMLG	4
GO:0006839	mitochondrial transport	12/665	254/18722	0.194258458991777	0.38951420575794	SLC25A37/HK2/BNIP3L/TSPO/BNIP3/DNAJC15/BLOC1S2/LRRK2/TIMM8B/MRPL18/HAX1/TIMM10	12
GO:0010565	regulation of cellular ketone metabolic process	7/665	133/18722	0.194841137256675	0.38951420575794	APOC1/CD74/ADM/IRS2/ANXA1/EGR1/INSIG2	7
GO:0046887	positive regulation of hormone secretion	7/665	133/18722	0.194841137256675	0.38951420575794	HLA-DRB1/GLUL/DYNLL1/IRS2/RAC1/EGFR/KIF5B	7
GO:0001709	cell fate determination	3/665	43/18722	0.19567951100818	0.38951420575794	KLF4/MCL1/IFRD1	3
GO:0006458	'de novo' protein folding	3/665	43/18722	0.19567951100818	0.38951420575794	CD74/ERO1A/PTGES3	3
GO:0016266	O-glycan processing	3/665	43/18722	0.19567951100818	0.38951420575794	B3GNT7/GCNT1/B3GNT5	3
GO:0035794	positive regulation of mitochondrial membrane permeability	3/665	43/18722	0.19567951100818	0.38951420575794	BNIP3L/BNIP3/BLOC1S2	3
GO:0098815	modulation of excitatory postsynaptic potential	3/665	43/18722	0.19567951100818	0.38951420575794	PTEN/LRRK2/PTK2B	3
GO:0098927	vesicle-mediated transport between endosomal compartments	3/665	43/18722	0.19567951100818	0.38951420575794	DAB2/MSN/FLNA	3
GO:1903793	positive regulation of anion transport	3/665	43/18722	0.19567951100818	0.38951420575794	CEBPB/PTAFR/KMO	3
GO:0001837	epithelial to mesenchymal transition	8/665	157/18722	0.196005804048187	0.38951420575794	S100A4/DAB2/PTEN/PDPN/FLNA/GLIPR2/SDCBP/SMAD7	8
GO:0051017	actin filament bundle assembly	8/665	157/18722	0.196005804048187	0.38951420575794	S100A10/RAC1/FLNA/RHOA/RHOC/PTK2B/MARCKS/NRP1	8
GO:0000966	RNA 5'-end processing	2/665	23/18722	0.19601107215304	0.38951420575794	SSB/RPP30	2
GO:0001919	regulation of receptor recycling	2/665	23/18722	0.19601107215304	0.38951420575794	ANXA2/CHMP5	2
GO:0002758	innate immune response-activating signal transduction	2/665	23/18722	0.19601107215304	0.38951420575794	CLEC7A/TYROBP	2
GO:0019430	removal of superoxide radicals	2/665	23/18722	0.19601107215304	0.38951420575794	SOD2/CD36	2
GO:0032740	positive regulation of interleukin-17 production	2/665	23/18722	0.19601107215304	0.38951420575794	MYD88/PHB	2
GO:0035640	exploration behavior	2/665	23/18722	0.19601107215304	0.38951420575794	APOE/LRRK2	2
GO:0035988	chondrocyte proliferation	2/665	23/18722	0.19601107215304	0.38951420575794	MMP14/SMAD7	2
GO:0043931	ossification involved in bone maturation	2/665	23/18722	0.19601107215304	0.38951420575794	SNX10/RHOA	2
GO:0045723	positive regulation of fatty acid biosynthetic process	2/665	23/18722	0.19601107215304	0.38951420575794	CD74/ANXA1	2
GO:0051131	chaperone-mediated protein complex assembly	2/665	23/18722	0.19601107215304	0.38951420575794	PTGES3/PFDN6	2
GO:0051457	maintenance of protein location in nucleus	2/665	23/18722	0.19601107215304	0.38951420575794	TXN/ARL2BP	2
GO:0060547	negative regulation of necrotic cell death	2/665	23/18722	0.19601107215304	0.38951420575794	NUPR1/YBX3	2
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	2/665	23/18722	0.19601107215304	0.38951420575794	HAMP/RGS2	2
GO:0071514	genetic imprinting	2/665	23/18722	0.19601107215304	0.38951420575794	KDM1B/IGF2	2
GO:1900273	positive regulation of long-term synaptic potentiation	2/665	23/18722	0.19601107215304	0.38951420575794	SQSTM1/EPHB2	2
GO:1902410	mitotic cytokinetic process	2/665	23/18722	0.19601107215304	0.38951420575794	RHOA/CHMP5	2
GO:2001169	regulation of ATP biosynthetic process	2/665	23/18722	0.19601107215304	0.38951420575794	TREM2/ENO1	2
GO:0016101	diterpenoid metabolic process	5/665	87/18722	0.196842940932898	0.390786767118372	DHRS3/EGFR/RBP1/CYP1B1/ALDH3A2	5
GO:0044070	regulation of anion transport	5/665	87/18722	0.196842940932898	0.390786767118372	CEBPB/RGS2/PTAFR/KMO/PRNP	5
GO:0006939	smooth muscle contraction	6/665	110/18722	0.196965966123043	0.390786767118372	SULF2/DOCK4/RHOA/RGS2/PTAFR/KCNMA1	6
GO:0061387	regulation of extent of cell growth	6/665	110/18722	0.196965966123043	0.390786767118372	VEGFA/APOE/DPYSL2/FN1/CXCL12/NRP1	6
GO:0008016	regulation of heart contraction	10/665	206/18722	0.198613208533386	0.393897704074593	CALM1/ADORA3/ADM/TMIGD3/CLIC2/FLNA/KCNE1/RGS2/CALM3/SMAD7	10
GO:0035418	protein localization to synapse	4/665	65/18722	0.199582755588113	0.395662662653738	RAB8A/RAP1A/KIF5B/STX3	4
GO:0098727	maintenance of cell number	7/665	134/18722	0.199797993429127	0.395931430359953	ZFP36L2/KLF4/KLF10/SPI1/EIF4E/ELAVL1/ZC3H13	7
GO:0009260	ribonucleotide biosynthetic process	9/665	182/18722	0.20001503561931	0.39620355800238	TREM2/ALDOA/ACSL1/UPP1/PAPSS1/CMPK1/ENO1/PAPSS2/GUK1	9
GO:0001843	neural tube closure	5/665	88/18722	0.20310360071439	0.402001153146364	ADM/ST14/CITED2/RALA/SETD2	5
GO:0030101	natural killer cell activation	5/665	88/18722	0.20310360071439	0.402001153146364	MERTK/HLA-F/NFIL3/HLA-E/TYROBP	5
GO:0030521	androgen receptor signaling pathway	3/665	44/18722	0.204871012853412	0.404693534929036	DAB2/RHOA/PHB	3
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	3/665	44/18722	0.204871012853412	0.404693534929036	MSN/RHOA/LIN7C	3
GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	3/665	44/18722	0.204871012853412	0.404693534929036	CD300A/PTK2B/CYP1B1	3
GO:0097178	ruffle assembly	3/665	44/18722	0.204871012853412	0.404693534929036	SNX10/RAC1/ABI3	3
GO:1903214	regulation of protein targeting to mitochondrion	3/665	44/18722	0.204871012853412	0.404693534929036	BNIP3L/LRRK2/HAX1	3
GO:1903169	regulation of calcium ion transmembrane transport	8/665	159/18722	0.205155709754294	0.40509490563323	CALM1/CLIC2/AHNAK/CALM3/C4orf3/PTK2B/DIAPH1/PRNP	8
GO:0055074	calcium ion homeostasis	20/665	460/18722	0.206069494726833	0.406737644476712	CXCR4/FPR3/APOE/CALM1/SNX10/ERO1A/ADM/C5AR1/CD36/CLIC2/BNIP3/CALM3/PTK2B/DIAPH1/CCL13/GRINA/HEXB/CXCL12/ATP2C1/PRNP	20
GO:0014015	positive regulation of gliogenesis	4/665	66/18722	0.206973803636458	0.407712962375424	CXCR4/TSPO/EGFR/TLR2	4
GO:0019229	regulation of vasoconstriction	4/665	66/18722	0.206973803636458	0.407712962375424	ADM/DOCK4/RHOA/EGFR	4
GO:0050922	negative regulation of chemotaxis	4/665	66/18722	0.206973803636458	0.407712962375424	DUSP1/MIF/RIN3/NRP1	4
GO:2000272	negative regulation of signaling receptor activity	4/665	66/18722	0.206973803636458	0.407712962375424	ERRFI1/LY6E/PTEN/EPHB2	4
GO:2000573	positive regulation of DNA biosynthetic process	4/665	66/18722	0.206973803636458	0.407712962375424	KLF4/PTGES3/HNRNPA1/PTK2B	4
GO:0010633	negative regulation of epithelial cell migration	6/665	112/18722	0.208059901099352	0.408044138560245	APOE/KLF4/CSNK2B/PTEN/RHOA/ACVRL1	6
GO:0035601	protein deacylation	6/665	112/18722	0.208059901099352	0.408044138560245	VEGFA/FLNA/LRRK2/MORF4L1/PHB/PER1	6
GO:0001779	natural killer cell differentiation	2/665	24/18722	0.209112358332584	0.408044138560245	MERTK/NFIL3	2
GO:0002438	acute inflammatory response to antigenic stimulus	2/665	24/18722	0.209112358332584	0.408044138560245	FCGR2B/HLA-E	2
GO:0007035	vacuolar acidification	2/665	24/18722	0.209112358332584	0.408044138560245	SLC11A1/GRN	2
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	2/665	24/18722	0.209112358332584	0.408044138560245	TYMP/UPP1	2
GO:0010288	response to lead ion	2/665	24/18722	0.209112358332584	0.408044138560245	PLSCR1/PPP2CB	2
GO:0016048	detection of temperature stimulus	2/665	24/18722	0.209112358332584	0.408044138560245	CXCR4/CXCL12	2
GO:0018230	peptidyl-L-cysteine S-palmitoylation	2/665	24/18722	0.209112358332584	0.408044138560245	ZDHHC20/GOLGA7	2
GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine	2/665	24/18722	0.209112358332584	0.408044138560245	ZDHHC20/GOLGA7	2
GO:0030810	positive regulation of nucleotide biosynthetic process	2/665	24/18722	0.209112358332584	0.408044138560245	TREM2/ENO1	2
GO:0030859	polarized epithelial cell differentiation	2/665	24/18722	0.209112358332584	0.408044138560245	MSN/RHOA	2
GO:0039531	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	2/665	24/18722	0.209112358332584	0.408044138560245	DDX60/OASL	2
GO:0044321	response to leptin	2/665	24/18722	0.209112358332584	0.408044138560245	PTEN/EBI3	2
GO:0048011	neurotrophin TRK receptor signaling pathway	2/665	24/18722	0.209112358332584	0.408044138560245	DDIT4/AKT1S1	2
GO:0048641	regulation of skeletal muscle tissue development	2/665	24/18722	0.209112358332584	0.408044138560245	YBX3/IGF2	2
GO:0051570	regulation of histone H3-K9 methylation	2/665	24/18722	0.209112358332584	0.408044138560245	LMNA/JARID2	2
GO:0060149	negative regulation of posttranscriptional gene silencing	2/665	24/18722	0.209112358332584	0.408044138560245	HIF1A-AS2/ELAVL1	2
GO:0060967	negative regulation of gene silencing by RNA	2/665	24/18722	0.209112358332584	0.408044138560245	HIF1A-AS2/ELAVL1	2
GO:0061162	establishment of monopolar cell polarity	2/665	24/18722	0.209112358332584	0.408044138560245	MSN/RHOA	2
GO:0071294	cellular response to zinc ion	2/665	24/18722	0.209112358332584	0.408044138560245	TSPO/MT1X	2
GO:0071676	negative regulation of mononuclear cell migration	2/665	24/18722	0.209112358332584	0.408044138560245	DUSP1/IL27RA	2
GO:1900373	positive regulation of purine nucleotide biosynthetic process	2/665	24/18722	0.209112358332584	0.408044138560245	TREM2/ENO1	2
GO:1903428	positive regulation of reactive oxygen species biosynthetic process	2/665	24/18722	0.209112358332584	0.408044138560245	SOD2/CD36	2
GO:0009199	ribonucleoside triphosphate metabolic process	5/665	89/18722	0.209430080666745	0.408183333691657	TREM2/ALDOA/ENO1/RHOA/LRRK2	5
GO:0051781	positive regulation of cell division	5/665	89/18722	0.209430080666745	0.408183333691657	VEGFA/RHOA/YBX1/IGF2/PPBP	5
GO:0060606	tube closure	5/665	89/18722	0.209430080666745	0.408183333691657	ADM/ST14/CITED2/RALA/SETD2	5
GO:0048588	developmental cell growth	11/665	234/18722	0.21174556962057	0.412534488833489	CXCR4/ALCAM/VEGFA/APOE/DPYSL2/HAMP/RGS2/FN1/CXCL12/SMAD7/NRP1	11
GO:0007369	gastrulation	9/665	185/18722	0.212904026259846	0.414628922614199	DUSP1/KLF4/MYADM/GPI/WNK1/MMP14/FN1/DUSP2/SETD2	9
GO:0044106	cellular amine metabolic process	6/665	113/18722	0.213688584082694	0.415993835836659	IL4I1/NR4A2/LY6E/ITGAM/OAZ1/KMO	6
GO:0035987	endodermal cell differentiation	3/665	45/18722	0.214158920040785	0.416051481079076	MMP14/FN1/SETD2	3
GO:0048538	thymus development	3/665	45/18722	0.214158920040785	0.416051481079076	MAFB/CITED2/JARID2	3
GO:0051180	vitamin transport	3/665	45/18722	0.214158920040785	0.416051481079076	SLC2A3/SLC25A19/TCN2	3
GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	3/665	45/18722	0.214158920040785	0.416051481079076	BNIP3L/BNIP3/BLOC1S2	3
GO:0032890	regulation of organic acid transport	4/665	67/18722	0.214442464329965	0.416051481079076	ACSL1/IRS2/RGS2/KMO	4
GO:0050435	amyloid-beta metabolic process	4/665	67/18722	0.214442464329965	0.416051481079076	APOE/RTN3/APH1A/PRNP	4
GO:0061077	chaperone-mediated protein folding	4/665	67/18722	0.214442464329965	0.416051481079076	CD74/ERO1A/FKBP5/PTGES3	4
GO:1902117	positive regulation of organelle assembly	4/665	67/18722	0.214442464329965	0.416051481079076	PIP4K2A/MSN/RHOA/SDCBP	4
GO:0061572	actin filament bundle organization	8/665	161/18722	0.214471608556256	0.416051481079076	S100A10/RAC1/FLNA/RHOA/RHOC/PTK2B/MARCKS/NRP1	8
GO:0000086	G2/M transition of mitotic cell cycle	7/665	137/18722	0.214955349296422	0.416664620126059	CALM1/CCNY/CALM3/PLK3/CDKN1A/FBXL15/FOXN3	7
GO:0007266	Rho protein signal transduction	7/665	137/18722	0.214955349296422	0.416664620126059	APOE/RAC1/PDPN/RHOA/RHOB/CFL1/NRP1	7
GO:0048738	cardiac muscle tissue development	11/665	236/18722	0.219479965765721	0.425269173432995	VEGFA/HAMP/LY6E/CITED2/PTEN/RGS2/LMNA/PLEC/CACYBP/JARID2/SMAD7	11
GO:0034394	protein localization to cell surface	4/665	68/18722	0.221984177673213	0.425586916203376	FLNA/KCNAB2/STX3/TYROBP	4
GO:0042987	amyloid precursor protein catabolic process	4/665	68/18722	0.221984177673213	0.425586916203376	APOE/RTN3/APH1A/PRNP	4
GO:0051926	negative regulation of calcium ion transport	4/665	68/18722	0.221984177673213	0.425586916203376	CALM1/CLIC2/CALM3/C4orf3	4
GO:0060411	cardiac septum morphogenesis	4/665	68/18722	0.221984177673213	0.425586916203376	CITED2/DHRS3/SMAD7/NRP1	4
GO:0061912	selective autophagy	4/665	68/18722	0.221984177673213	0.425586916203376	MAP1LC3B/SQSTM1/WIPI2/RIPK2	4
GO:1904888	cranial skeletal system development	4/665	68/18722	0.221984177673213	0.425586916203376	INSIG2/MMP14/FOXN3/SETD2	4
GO:0051492	regulation of stress fiber assembly	5/665	91/18722	0.222269526898975	0.425586916203376	S100A10/RAC1/RHOA/RHOC/NRP1	5
GO:0055006	cardiac cell development	5/665	91/18722	0.222269526898975	0.425586916203376	VEGFA/HAMP/RGS2/LMNA/PLEC	5
GO:0098661	inorganic anion transmembrane transport	5/665	91/18722	0.222269526898975	0.425586916203376	SLC1A3/CLIC2/GABRB2/PTAFR/PRNP	5
GO:0006658	phosphatidylserine metabolic process	2/665	25/18722	0.222298518000798	0.425586916203376	PLSCR1/SERINC1	2
GO:0010996	response to auditory stimulus	2/665	25/18722	0.222298518000798	0.425586916203376	SLC1A3/XPC	2
GO:0032925	regulation of activin receptor signaling pathway	2/665	25/18722	0.222298518000798	0.425586916203376	CSNK2B/SMAD7	2
GO:0033622	integrin activation	2/665	25/18722	0.222298518000798	0.425586916203376	FN1/CXCL12	2
GO:0045109	intermediate filament organization	2/665	25/18722	0.222298518000798	0.425586916203376	VIM/PLEC	2
GO:0045324	late endosome to vacuole transport	2/665	25/18722	0.222298518000798	0.425586916203376	VTA1/CHMP5	2
GO:0046039	GTP metabolic process	2/665	25/18722	0.222298518000798	0.425586916203376	RHOA/LRRK2	2
GO:0046835	carbohydrate phosphorylation	2/665	25/18722	0.222298518000798	0.425586916203376	HK2/GALK1	2
GO:0050951	sensory perception of temperature stimulus	2/665	25/18722	0.222298518000798	0.425586916203376	CXCR4/CXCL12	2
GO:0051204	protein insertion into mitochondrial membrane	2/665	25/18722	0.222298518000798	0.425586916203376	TIMM8B/TIMM10	2
GO:0060706	cell differentiation involved in embryonic placenta development	2/665	25/18722	0.222298518000798	0.425586916203376	ST14/SOCS3	2
GO:0061339	establishment or maintenance of monopolar cell polarity	2/665	25/18722	0.222298518000798	0.425586916203376	MSN/RHOA	2
GO:0062149	detection of stimulus involved in sensory perception of pain	2/665	25/18722	0.222298518000798	0.425586916203376	CXCR4/CXCL12	2
GO:0071450	cellular response to oxygen radical	2/665	25/18722	0.222298518000798	0.425586916203376	SOD2/CD36	2
GO:0071451	cellular response to superoxide	2/665	25/18722	0.222298518000798	0.425586916203376	SOD2/CD36	2
GO:0086013	membrane repolarization during cardiac muscle cell action potential	2/665	25/18722	0.222298518000798	0.425586916203376	FLNA/KCNE1	2
GO:0086064	cell communication by electrical coupling involved in cardiac conduction	2/665	25/18722	0.222298518000798	0.425586916203376	CALM1/CALM3	2
GO:0090312	positive regulation of protein deacetylation	2/665	25/18722	0.222298518000798	0.425586916203376	VEGFA/LRRK2	2
GO:0090330	regulation of platelet aggregation	2/665	25/18722	0.222298518000798	0.425586916203376	CD9/PDPN	2
GO:0090382	phagosome maturation	2/665	25/18722	0.222298518000798	0.425586916203376	RAB20/RAB31	2
GO:1901623	regulation of lymphocyte chemotaxis	2/665	25/18722	0.222298518000798	0.425586916203376	WNK1/PTK2B	2
GO:1903055	positive regulation of extracellular matrix organization	2/665	25/18722	0.222298518000798	0.425586916203376	PDPN/RB1	2
GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	3/665	46/18722	0.223534304214485	0.426801956183631	ALCAM/JAML/CADM1	3
GO:0031057	negative regulation of histone modification	3/665	46/18722	0.223534304214485	0.426801956183631	UBE2B/SPI1/JARID2	3
GO:0042398	cellular modified amino acid biosynthetic process	3/665	46/18722	0.223534304214485	0.426801956183631	PLSCR1/GATM/HAGH	3
GO:0045851	pH reduction	3/665	46/18722	0.223534304214485	0.426801956183631	SLC11A1/RAB20/GRN	3
GO:0060976	coronary vasculature development	3/665	46/18722	0.223534304214485	0.426801956183631	VEGFA/SETD2/NRP1	3
GO:0061462	protein localization to lysosome	3/665	46/18722	0.223534304214485	0.426801956183631	LAMTOR5/SCARB2/CD81	3
GO:0071827	plasma lipoprotein particle organization	3/665	46/18722	0.223534304214485	0.426801956183631	APOE/APOC1/SOAT1	3
GO:0050657	nucleic acid transport	8/665	163/18722	0.223945594341702	0.427258965020445	MX2/SSB/ZFP36/NUP58/YBX1/HNRNPA1/MRPL18/SETD2	8
GO:0050658	RNA transport	8/665	163/18722	0.223945594341702	0.427258965020445	MX2/SSB/ZFP36/NUP58/YBX1/HNRNPA1/MRPL18/SETD2	8
GO:0000077	DNA damage checkpoint signaling	6/665	115/18722	0.225100184186153	0.428960286977409	RPS27L/RPA2/PLK3/CDKN1A/FOXN3/XPC	6
GO:0043279	response to alkaloid	6/665	115/18722	0.225100184186153	0.428960286977409	CXCR4/SLC1A3/FOSB/PEA15/GPI/PTK2B	6
GO:0051209	release of sequestered calcium ion into cytosol	6/665	115/18722	0.225100184186153	0.428960286977409	CALM1/ERO1A/CLIC2/CALM3/PTK2B/DIAPH1	6
GO:0061564	axon development	20/665	467/18722	0.225182573183916	0.428960286977409	ALCAM/VEGFA/APOE/KLF4/S100A6/NR4A2/DPYSL2/RAB8A/TSPO/SKIL/PTEN/RAC1/FLNA/GRN/KIF5B/EPHB2/FN1/CXCL12/SIPA1L1/NRP1	20
GO:1903311	regulation of mRNA metabolic process	13/665	288/18722	0.226091861607701	0.430527414632289	VIM/SLC11A1/ZFP36L2/YBX3/ZFP36/MYD88/YBX1/NCL/LARP7/HNRNPA0/HNRNPA1/TOB1/ELAVL1	13
GO:0051259	protein complex oligomerization	11/665	238/18722	0.227327763597771	0.432715045990394	ISG15/HLA-DRB1/B2M/CD74/ALDOA/SOD2/MIF/PYCARD/ALOX5AP/ELAVL1/PRNP	11
GO:0006497	protein lipidation	5/665	92/18722	0.228776967581834	0.434973805999125	GLUL/ZDHHC20/GOLGA7/WDR45B/WIPI2	5
GO:0032465	regulation of cytokinesis	5/665	92/18722	0.228776967581834	0.434973805999125	CALM1/RHOA/CALM3/PLK3/SETD2	5
GO:0034502	protein localization to chromosome	5/665	92/18722	0.228776967581834	0.434973805999125	TERF2IP/RPA2/SPI1/RB1/SETD2	5
GO:0006368	transcription elongation from RNA polymerase II promoter	4/665	69/18722	0.229594397198482	0.435861021419578	LARP7/EAF1/EAPP/SETD2	4
GO:0007004	telomere maintenance via telomerase	4/665	69/18722	0.229594397198482	0.435861021419578	TERF2IP/NOP10/PTGES3/HNRNPA1	4
GO:0034605	cellular response to heat	4/665	69/18722	0.229594397198482	0.435861021419578	HMOX1/IER5/SLU7/CDKN1A	4
GO:0050805	negative regulation of synaptic transmission	4/665	69/18722	0.229594397198482	0.435861021419578	RAP1A/PTEN/LRRK2/PTK2B	4
GO:0050768	negative regulation of neurogenesis	7/665	140/18722	0.230515299524616	0.437298197189961	TREM2/B2M/YWHAH/TSPO/PTEN/EPHB2/NRP1	7
GO:0046578	regulation of Ras protein signal transduction	9/665	189/18722	0.230583537672481	0.437298197189961	APOE/FBP1/SHOC2/RAC1/PPP2CB/SQSTM1/PIK3CB/EPHB2/NRP1	9
GO:0015833	peptide transport	12/665	264/18722	0.230693039043457	0.437298197189961	HLA-DRB1/CD74/ALOX5/GLUL/DYNLL1/IRS2/RAC1/ANXA1/EGFR/S100A8/KIF5B/SLC16A10	12
GO:0030518	intracellular steroid hormone receptor signaling pathway	6/665	116/18722	0.230879370105927	0.437298197189961	YWHAH/DAB2/RHOA/PTGES3/PHB/PER1	6
GO:0051283	negative regulation of sequestering of calcium ion	6/665	116/18722	0.230879370105927	0.437298197189961	CALM1/ERO1A/CLIC2/CALM3/PTK2B/DIAPH1	6
GO:0098732	macromolecule deacylation	6/665	116/18722	0.230879370105927	0.437298197189961	VEGFA/FLNA/LRRK2/MORF4L1/PHB/PER1	6
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	3/665	47/18722	0.232988411385613	0.439117332038869	SLC2A5/SOD2/RHOA	3
GO:0007595	lactation	3/665	47/18722	0.232988411385613	0.439117332038869	OAS2/VEGFA/HK2	3
GO:0010712	regulation of collagen metabolic process	3/665	47/18722	0.232988411385613	0.439117332038869	VIM/ERRFI1/RAP1A	3
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	3/665	47/18722	0.232988411385613	0.439117332038869	CARD16/PYCARD/TNFAIP3	3
GO:0014911	positive regulation of smooth muscle cell migration	3/665	47/18722	0.232988411385613	0.439117332038869	DOCK4/S100A11/NRP1	3
GO:0032008	positive regulation of TOR signaling	3/665	47/18722	0.232988411385613	0.439117332038869	TREM2/LAMTOR5/RRAGD	3
GO:0045601	regulation of endothelial cell differentiation	3/665	47/18722	0.232988411385613	0.439117332038869	VEGFA/BTG1/ACVRL1	3
GO:0046677	response to antibiotic	3/665	47/18722	0.232988411385613	0.439117332038869	CRIP1/SLC1A3/PPP2CB	3
GO:0047496	vesicle transport along microtubule	3/665	47/18722	0.232988411385613	0.439117332038869	BLOC1S1/BLOC1S2/KIF5B	3
GO:0051489	regulation of filopodium assembly	3/665	47/18722	0.232988411385613	0.439117332038869	RALA/AGRN/NRP1	3
GO:0072583	clathrin-dependent endocytosis	3/665	47/18722	0.232988411385613	0.439117332038869	DAB2/FCHO2/PIK3CB	3
GO:0090279	regulation of calcium ion import	3/665	47/18722	0.232988411385613	0.439117332038869	LGALS3/CXCL12/PRNP	3
GO:0120163	negative regulation of cold-induced thermogenesis	3/665	47/18722	0.232988411385613	0.439117332038869	ARRDC3/TLE3/RB1	3
GO:0046661	male sex differentiation	8/665	165/18722	0.233569535964755	0.439712346115467	NUPR1/LHFPL2/YBX3/HSD17B4/CITED2/FLNA/MMP14/RAB13	8
GO:0071772	response to BMP	8/665	165/18722	0.233569535964755	0.439712346115467	SKIL/SMURF2/EGR1/ACVRL1/FBXL15/UBE2D1/TOB1/SMAD7	8
GO:0071773	cellular response to BMP stimulus	8/665	165/18722	0.233569535964755	0.439712346115467	SKIL/SMURF2/EGR1/ACVRL1/FBXL15/UBE2D1/TOB1/SMAD7	8
GO:0046390	ribose phosphate biosynthetic process	9/665	190/18722	0.235086345499175	0.440101037206879	TREM2/ALDOA/ACSL1/UPP1/PAPSS1/CMPK1/ENO1/PAPSS2/GUK1	9
GO:0019217	regulation of fatty acid metabolic process	5/665	93/18722	0.235339184701417	0.440101037206879	APOC1/CD74/IRS2/ANXA1/INSIG2	5
GO:0060993	kidney morphogenesis	5/665	93/18722	0.235339184701417	0.440101037206879	VEGFA/STAT1/PRKX/LRRK2/GCNT1	5
GO:1901019	regulation of calcium ion transmembrane transporter activity	5/665	93/18722	0.235339184701417	0.440101037206879	CALM1/CLIC2/AHNAK/CALM3/C4orf3	5
GO:0001556	oocyte maturation	2/665	26/18722	0.235547033998048	0.440101037206879	ANG/PTK2B	2
GO:0001573	ganglioside metabolic process	2/665	26/18722	0.235547033998048	0.440101037206879	ST8SIA4/HEXB	2
GO:0014829	vascular associated smooth muscle contraction	2/665	26/18722	0.235547033998048	0.440101037206879	DOCK4/RHOA	2
GO:0021952	central nervous system projection neuron axonogenesis	2/665	26/18722	0.235547033998048	0.440101037206879	NR4A2/EPHB2	2
GO:0032515	negative regulation of phosphoprotein phosphatase activity	2/665	26/18722	0.235547033998048	0.440101037206879	PPP1R15A/LGALS3	2
GO:0033522	histone H2A ubiquitination	2/665	26/18722	0.235547033998048	0.440101037206879	UBE2B/DTX3L	2
GO:0033598	mammary gland epithelial cell proliferation	2/665	26/18722	0.235547033998048	0.440101037206879	CEBPB/GPX1	2
GO:0046639	negative regulation of alpha-beta T cell differentiation	2/665	26/18722	0.235547033998048	0.440101037206879	ANXA1/SMAD7	2
GO:0046697	decidualization	2/665	26/18722	0.235547033998048	0.440101037206879	JUNB/CITED2	2
GO:0046755	viral budding	2/665	26/18722	0.235547033998048	0.440101037206879	VTA1/CHMP5	2
GO:0048499	synaptic vesicle membrane organization	2/665	26/18722	0.235547033998048	0.440101037206879	STX3/SYNGR2	2
GO:0051016	barbed-end actin filament capping	2/665	26/18722	0.235547033998048	0.440101037206879	CAPG/GSN	2
GO:0060352	cell adhesion molecule production	2/665	26/18722	0.235547033998048	0.440101037206879	CXCL8/GCNT1	2
GO:0070977	bone maturation	2/665	26/18722	0.235547033998048	0.440101037206879	SNX10/RHOA	2
GO:0099637	neurotransmitter receptor transport	2/665	26/18722	0.235547033998048	0.440101037206879	RAB8A/STX3	2
GO:1900017	positive regulation of cytokine production involved in inflammatory response	2/665	26/18722	0.235547033998048	0.440101037206879	CLEC7A/MYD88	2
GO:0006119	oxidative phosphorylation	7/665	141/18722	0.235785133753119	0.440214919140872	NUPR1/SDHD/DNAJC15/RHOA/COA6/CYCS/COX5B	7
GO:0008584	male gonad development	7/665	141/18722	0.235785133753119	0.440214919140872	NUPR1/YBX3/HSD17B4/CITED2/FLNA/MMP14/RAB13	7
GO:0060485	mesenchyme development	13/665	291/18722	0.236909307276912	0.442147674489769	S100A4/STAT1/DAB2/CITED2/PTEN/PDPN/FLNA/GLIPR2/SDCBP/ACVRL1/FN1/SMAD7/NRP1	13
GO:0051236	establishment of RNA localization	8/665	166/18722	0.238435144310322	0.444828328536899	MX2/SSB/ZFP36/NUP58/YBX1/HNRNPA1/MRPL18/SETD2	8
GO:0007009	plasma membrane organization	7/665	142/18722	0.241094270598093	0.449451809779641	CXCR4/CD9/NDRG1/PLSCR1/GSN/PTEN/PLEC	7
GO:0097553	calcium ion transmembrane import into cytosol	7/665	142/18722	0.241094270598093	0.449451809779641	CALM1/ERO1A/CLIC2/CALM3/PTK2B/DIAPH1/PRNP	7
GO:0001738	morphogenesis of a polarized epithelium	5/665	94/18722	0.2419533935411	0.449850054611443	DAB2/MSN/SMURF2/RAC1/RHOA	5
GO:0014020	primary neural tube formation	5/665	94/18722	0.2419533935411	0.449850054611443	ADM/ST14/CITED2/RALA/SETD2	5
GO:1902414	protein localization to cell junction	5/665	94/18722	0.2419533935411	0.449850054611443	RAB8A/RAP1A/FLNA/KIF5B/STX3	5
GO:0010569	regulation of double-strand break repair via homologous recombination	3/665	48/18722	0.242512672728771	0.449850054611443	TERF2IP/RPA2/SETD2	3
GO:0033628	regulation of cell adhesion mediated by integrin	3/665	48/18722	0.242512672728771	0.449850054611443	WNK1/PLAU/CYP1B1	3
GO:0045912	negative regulation of carbohydrate metabolic process	3/665	48/18722	0.242512672728771	0.449850054611443	NUPR1/DDIT4/FBP1	3
GO:1902003	regulation of amyloid-beta formation	3/665	48/18722	0.242512672728771	0.449850054611443	APOE/RTN3/PRNP	3
GO:1905710	positive regulation of membrane permeability	3/665	48/18722	0.242512672728771	0.449850054611443	BNIP3L/BNIP3/BLOC1S2	3
GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	3/665	48/18722	0.242512672728771	0.449850054611443	N4BP1/SDCBP/CAMLG	3
GO:0007613	memory	6/665	118/18722	0.242575079750235	0.449850054611443	TREM2/APOE/SGK1/CEBPB/PTEN/PRNP	6
GO:0009308	amine metabolic process	6/665	118/18722	0.242575079750235	0.449850054611443	IL4I1/NR4A2/LY6E/ITGAM/OAZ1/KMO	6
GO:0022612	gland morphogenesis	6/665	118/18722	0.242575079750235	0.449850054611443	SULF2/CRIP1/CEBPB/MSN/TNFAIP3/NRP1	6
GO:0030203	glycosaminoglycan metabolic process	6/665	118/18722	0.242575079750235	0.449850054611443	CD44/IDS/LYVE1/B3GNT7/CHST15/HEXB	6
GO:0051282	regulation of sequestering of calcium ion	6/665	118/18722	0.242575079750235	0.449850054611443	CALM1/ERO1A/CLIC2/CALM3/PTK2B/DIAPH1	6
GO:0055088	lipid homeostasis	8/665	167/18722	0.243335104094483	0.451091185135987	TREM2/APOE/CNBP/IRS2/RBP1/SOAT1/ANGPTL4/ABHD5	8
GO:0000281	mitotic cytokinesis	4/665	71/18722	0.245002277322107	0.453843204730106	RHOA/RHOB/RHOC/CHMP5	4
GO:0071230	cellular response to amino acid stimulus	4/665	71/18722	0.245002277322107	0.453843204730106	CAPN2/CEBPB/LAMTOR5/RRAGD	4
GO:0006874	cellular calcium ion homeostasis	19/665	448/18722	0.245179033201833	0.45400141393931	CXCR4/FPR3/APOE/CALM1/ERO1A/ADM/C5AR1/CD36/CLIC2/BNIP3/CALM3/PTK2B/DIAPH1/CCL13/GRINA/HEXB/CXCL12/ATP2C1/PRNP	19
GO:0010948	negative regulation of cell cycle process	13/665	294/18722	0.247926386695045	0.457028558644863	ATF5/GPNMB/DUSP1/ZFP36L2/KLF4/RPS27L/PTEN/RPA2/PLK3/CDKN1A/FOXN3/RB1/XPC	13
GO:0016482	cytosolic transport	8/665	168/18722	0.248268347558586	0.457028558644863	DAB2/PIP4K2A/TANC2/MSN/FLNA/LRRK2/KIF5B/VPS13A	8
GO:0010906	regulation of glucose metabolic process	6/665	119/18722	0.248487796120256	0.457028558644863	FBP1/IRS2/PPP1CB/PPP1R3B/PHLDA2/IGF2	6
GO:0042773	ATP synthesis coupled electron transport	5/665	95/18722	0.248616806931071	0.457028558644863	SDHD/DNAJC15/COA6/CYCS/COX5B	5
GO:0042775	mitochondrial ATP synthesis coupled electron transport	5/665	95/18722	0.248616806931071	0.457028558644863	SDHD/DNAJC15/COA6/CYCS/COX5B	5
GO:0042982	amyloid precursor protein metabolic process	5/665	95/18722	0.248616806931071	0.457028558644863	APOE/SOAT1/RTN3/APH1A/PRNP	5
GO:0048709	oligodendrocyte differentiation	5/665	95/18722	0.248616806931071	0.457028558644863	CXCR4/CD9/BNIP3/PTEN/TLR2	5
GO:0006783	heme biosynthetic process	2/665	27/18722	0.248836877201811	0.457028558644863	TSPO/UROD	2
GO:0010894	negative regulation of steroid biosynthetic process	2/665	27/18722	0.248836877201811	0.457028558644863	APOE/INSIG2	2
GO:0018904	ether metabolic process	2/665	27/18722	0.248836877201811	0.457028558644863	ALOX5/TXN	2
GO:0033688	regulation of osteoblast proliferation	2/665	27/18722	0.248836877201811	0.457028558644863	EIF2AK2/RHOA	2
GO:0042402	cellular biogenic amine catabolic process	2/665	27/18722	0.248836877201811	0.457028558644863	IL4I1/KMO	2
GO:0042403	thyroid hormone metabolic process	2/665	27/18722	0.248836877201811	0.457028558644863	CGA/SLC16A10	2
GO:0046174	polyol catabolic process	2/665	27/18722	0.248836877201811	0.457028558644863	TPI1/PTEN	2
GO:0061437	renal system vasculature development	2/665	27/18722	0.248836877201811	0.457028558644863	EGR1/NRP1	2
GO:0061440	kidney vasculature development	2/665	27/18722	0.248836877201811	0.457028558644863	EGR1/NRP1	2
GO:0098901	regulation of cardiac muscle cell action potential	2/665	27/18722	0.248836877201811	0.457028558644863	CALM1/CALM3	2
GO:1902883	negative regulation of response to oxidative stress	2/665	27/18722	0.248836877201811	0.457028558644863	LRRK2/TXN	2
GO:1902914	regulation of protein polyubiquitination	2/665	27/18722	0.248836877201811	0.457028558644863	NMI/UBE2D1	2
GO:1903203	regulation of oxidative stress-induced neuron death	2/665	27/18722	0.248836877201811	0.457028558644863	TREM2/MCL1	2
GO:1903205	regulation of hydrogen peroxide-induced cell death	2/665	27/18722	0.248836877201811	0.457028558644863	LRRK2/TXN	2
GO:2000463	positive regulation of excitatory postsynaptic potential	2/665	27/18722	0.248836877201811	0.457028558644863	PTEN/PTK2B	2
GO:0002762	negative regulation of myeloid leukocyte differentiation	3/665	49/18722	0.252098713975402	0.460636253109466	MAFB/C1QC/TRIB1	3
GO:0006778	porphyrin-containing compound metabolic process	3/665	49/18722	0.252098713975402	0.460636253109466	TSPO/HMOX1/UROD	3
GO:0008038	neuron recognition	3/665	49/18722	0.252098713975402	0.460636253109466	CXCR4/EPHB2/NRP1	3
GO:0030857	negative regulation of epithelial cell differentiation	3/665	49/18722	0.252098713975402	0.460636253109466	VEGFA/STAT1/ACVRL1	3
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	3/665	49/18722	0.252098713975402	0.460636253109466	RBX1/FBXL15/FBXL5	3
GO:0034332	adherens junction organization	3/665	49/18722	0.252098713975402	0.460636253109466	VEGFA/PLEC/SMAD7	3
GO:0035088	establishment or maintenance of apical/basal cell polarity	3/665	49/18722	0.252098713975402	0.460636253109466	MSN/RHOA/LIN7C	3
GO:0038084	vascular endothelial growth factor signaling pathway	3/665	49/18722	0.252098713975402	0.460636253109466	VEGFA/PIK3CB/NRP1	3
GO:0045778	positive regulation of ossification	3/665	49/18722	0.252098713975402	0.460636253109466	ISG15/ALOX5/FBN2	3
GO:0046580	negative regulation of Ras protein signal transduction	3/665	49/18722	0.252098713975402	0.460636253109466	FBP1/PPP2CB/EPHB2	3
GO:0048168	regulation of neuronal synaptic plasticity	3/665	49/18722	0.252098713975402	0.460636253109466	APOE/RAB8A/EPHB2	3
GO:0051932	synaptic transmission, GABAergic	3/665	49/18722	0.252098713975402	0.460636253109466	PTEN/GABRB2/KIF5B	3
GO:0061245	establishment or maintenance of bipolar cell polarity	3/665	49/18722	0.252098713975402	0.460636253109466	MSN/RHOA/LIN7C	3
GO:0072666	establishment of protein localization to vacuole	3/665	49/18722	0.252098713975402	0.460636253109466	TNFAIP3/SCARB2/VPS13A	3
GO:0071805	potassium ion transmembrane transport	10/665	219/18722	0.252743947850362	0.461053626777355	TREM2/SLC1A3/KCNQ3/PTEN/FLNA/KCNE1/WNK1/KCNAB2/KCNMA1/PRNP	10
GO:0001736	establishment of planar polarity	4/665	72/18722	0.252790972428228	0.461053626777355	DAB2/SMURF2/RAC1/RHOA	4
GO:0007164	establishment of tissue polarity	4/665	72/18722	0.252790972428228	0.461053626777355	DAB2/SMURF2/RAC1/RHOA	4
GO:0035567	non-canonical Wnt signaling pathway	4/665	72/18722	0.252790972428228	0.461053626777355	DAB2/SMURF2/RAC1/RHOA	4
GO:0051057	positive regulation of small GTPase mediated signal transduction	4/665	72/18722	0.252790972428228	0.461053626777355	SHOC2/RAC1/SOS2/PIK3CB	4
GO:0021543	pallium development	8/665	169/18722	0.253233797874348	0.461691847188375	SLC38A2/BNIP3/PTEN/FLNA/RHOA/UBA6/KIF5B/BCL2A1	8
GO:0003073	regulation of systemic arterial blood pressure	5/665	96/18722	0.255326638574416	0.465166200042099	SLC2A5/ADM/SOD2/RHOA/WNK1	5
GO:0055017	cardiac muscle tissue growth	5/665	96/18722	0.255326638574416	0.465166200042099	HAMP/CITED2/PTEN/RGS2/JARID2	5
GO:0043087	regulation of GTPase activity	15/665	348/18722	0.257169816468014	0.468352505623316	RGS1/LIMS1/S100A10/RAP1A/PYCARD/RAPGEF1/LRRK2/WNK1/PTK2B/DOCK8/CCL13/AGRN/IQGAP2/CPEB2/SIPA1L1	15
GO:0045931	positive regulation of mitotic cell cycle	6/665	121/18722	0.260433372931832	0.472570799627804	ANXA1/EIF4EBP1/EGFR/DYNLT3/RB1/EIF4E	6
GO:0035773	insulin secretion involved in cellular response to glucose stimulus	4/665	73/18722	0.260630254559796	0.472570799627804	HLA-DRB1/DYNLL1/RAC1/KIF5B	4
GO:0051962	positive regulation of nervous system development	12/665	272/18722	0.261637369683379	0.472570799627804	CXCR4/VEGFA/IL1RAP/TSPO/SKIL/EGFR/EPHB2/FN1/TLR2/AGRN/CXCL12/NRP1	12
GO:0006220	pyrimidine nucleotide metabolic process	3/665	50/18722	0.261738363504374	0.472570799627804	TYMP/UPP1/CMPK1	3
GO:0008089	anterograde axonal transport	3/665	50/18722	0.261738363504374	0.472570799627804	BLOC1S1/BLOC1S2/KIF5B	3
GO:0038093	Fc receptor signaling pathway	3/665	50/18722	0.261738363504374	0.472570799627804	FCGR2B/MYO1G/RAP1A	3
GO:0071825	protein-lipid complex subunit organization	3/665	50/18722	0.261738363504374	0.472570799627804	APOE/APOC1/SOAT1	3
GO:0099054	presynapse assembly	3/665	50/18722	0.261738363504374	0.472570799627804	IL1RAP/PTEN/SDCBP	3
GO:1902930	regulation of alcohol biosynthetic process	3/665	50/18722	0.261738363504374	0.472570799627804	APOE/PTAFR/PTK2B	3
GO:1903747	regulation of establishment of protein localization to mitochondrion	3/665	50/18722	0.261738363504374	0.472570799627804	BNIP3L/LRRK2/HAX1	3
GO:2000677	regulation of transcription regulatory region DNA binding	3/665	50/18722	0.261738363504374	0.472570799627804	KLF4/LAMTOR5/RB1	3
GO:0006721	terpenoid metabolic process	5/665	97/18722	0.262080106254713	0.472570799627804	DHRS3/EGFR/RBP1/CYP1B1/ALDH3A2	5
GO:0010596	negative regulation of endothelial cell migration	5/665	97/18722	0.262080106254713	0.472570799627804	APOE/KLF4/CSNK2B/RHOA/ACVRL1	5
GO:0070252	actin-mediated cell contraction	5/665	97/18722	0.262080106254713	0.472570799627804	GSN/PDPN/FLNA/KCNE1/MYL6	5
GO:0000303	response to superoxide	2/665	28/18722	0.262148429491721	0.472570799627804	SOD2/CD36	2
GO:0000423	mitophagy	2/665	28/18722	0.262148429491721	0.472570799627804	MAP1LC3B/SQSTM1	2
GO:0006972	hyperosmotic response	2/665	28/18722	0.262148429491721	0.472570799627804	YBX3/ERRFI1	2
GO:0009065	glutamine family amino acid catabolic process	2/665	28/18722	0.262148429491721	0.472570799627804	GLUL/DDAH2	2
GO:0019098	reproductive behavior	2/665	28/18722	0.262148429491721	0.472570799627804	PTEN/HEXB	2
GO:0032438	melanosome organization	2/665	28/18722	0.262148429491721	0.472570799627804	BLOC1S1/BLOC1S2	2
GO:0032958	inositol phosphate biosynthetic process	2/665	28/18722	0.262148429491721	0.472570799627804	PTAFR/PTK2B	2
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	2/665	28/18722	0.262148429491721	0.472570799627804	ERRFI1/EGFR	2
GO:0050996	positive regulation of lipid catabolic process	2/665	28/18722	0.262148429491721	0.472570799627804	IRS2/ABHD5	2
GO:0060765	regulation of androgen receptor signaling pathway	2/665	28/18722	0.262148429491721	0.472570799627804	DAB2/PHB	2
GO:0070076	histone lysine demethylation	2/665	28/18722	0.262148429491721	0.472570799627804	UBE2B/KDM1B	2
GO:0071280	cellular response to copper ion	2/665	28/18722	0.262148429491721	0.472570799627804	MT1X/PRNP	2
GO:0086011	membrane repolarization during action potential	2/665	28/18722	0.262148429491721	0.472570799627804	FLNA/KCNE1	2
GO:0099623	regulation of cardiac muscle cell membrane repolarization	2/665	28/18722	0.262148429491721	0.472570799627804	FLNA/KCNE1	2
GO:0045664	regulation of neuron differentiation	9/665	196/18722	0.262735626477875	0.47345760101343	B2M/YWHAH/DPYSL2/PTEN/RHOA/LRRK2/MMD/EIF4E/CXCL12	9
GO:0008544	epidermis development	14/665	324/18722	0.263704000183881	0.47503040265092	HLA-DRB1/TXNIP/KLF4/ERRFI1/ST14/ZFP36/ANXA1/YBX1/EGFR/PLEC/EMP1/AGPAT2/ALDH3A2/ATP2C1	14
GO:0044282	small molecule catabolic process	16/665	376/18722	0.264244192592292	0.475831027965105	IL4I1/APOE/HK2/GLUL/HSD17B4/UPP1/TPI1/IRS2/ENO1/ALDH2/PTEN/DDAH2/ESD/KMO/GALK1/HAGH	16
GO:0051208	sequestering of calcium ion	6/665	122/18722	0.266462385575468	0.479477934942098	CALM1/ERO1A/CLIC2/CALM3/PTK2B/DIAPH1	6
GO:0051928	positive regulation of calcium ion transport	6/665	122/18722	0.266462385575468	0.479477934942098	CALM1/LILRA5/TSPO/LGALS3/CALM3/CXCL12	6
GO:0001678	cellular glucose homeostasis	8/665	172/18722	0.268312502673791	0.482299685131046	HLA-DRB1/TREM2/LGALS1/HK2/DYNLL1/IRS2/RAC1/KIF5B	8
GO:1990138	neuron projection extension	8/665	172/18722	0.268312502673791	0.482299685131046	CXCR4/ALCAM/VEGFA/APOE/DPYSL2/FN1/CXCL12/NRP1	8
GO:0003151	outflow tract morphogenesis	4/665	74/18722	0.268515740192677	0.482299685131046	VEGFA/CITED2/DHRS3/NRP1	4
GO:0030968	endoplasmic reticulum unfolded protein response	4/665	74/18722	0.268515740192677	0.482299685131046	EIF2AK2/ERO1A/ATF3/PPP1R15A	4
GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	4/665	74/18722	0.268515740192677	0.482299685131046	DAB2/RHOA/PHB/PER1	4
GO:0010656	negative regulation of muscle cell apoptotic process	3/665	51/18722	0.27142365922439	0.486467935934086	NUPR1/HMOX1/PTK2B	3
GO:0010874	regulation of cholesterol efflux	3/665	51/18722	0.27142365922439	0.486467935934086	TREM2/APOE/NFKBIA	3
GO:0021872	forebrain generation of neurons	3/665	51/18722	0.27142365922439	0.486467935934086	B2M/RHOA/NRP1	3
GO:0032964	collagen biosynthetic process	3/665	51/18722	0.27142365922439	0.486467935934086	VIM/ERRFI1/RAP1A	3
GO:0060043	regulation of cardiac muscle cell proliferation	3/665	51/18722	0.27142365922439	0.486467935934086	CITED2/PTEN/JARID2	3
GO:1903307	positive regulation of regulated secretory pathway	3/665	51/18722	0.27142365922439	0.486467935934086	HLA-F/ITGAM/PTAFR	3
GO:0031570	DNA integrity checkpoint signaling	6/665	123/18722	0.272526311194628	0.488092168157586	RPS27L/RPA2/PLK3/CDKN1A/FOXN3/XPC	6
GO:0071482	cellular response to light stimulus	6/665	123/18722	0.272526311194628	0.488092168157586	TIMP1/CRIP1/CARD16/N4BP1/CDKN1A/XPC	6
GO:0002181	cytoplasmic translation	7/665	148/18722	0.273695930804802	0.489297051170193	PKM/YBX3/CNBP/RPL26L1/ZNF385A/CPEB2/RPL39	7
GO:0042886	amide transport	13/665	301/18722	0.274345194137671	0.489297051170193	HLA-DRB1/CD74/ALOX5/GLUL/DYNLL1/IRS2/RAC1/ANXA1/EGFR/S100A8/KIF5B/SLC16A10/PSAP	13
GO:0032984	protein-containing complex disassembly	10/665	224/18722	0.274804301281628	0.489297051170193	CAPG/DDIT4/CALM1/GSN/MAP1LC3B/BNIP3/KIF5B/VTA1/CFL1/CHMP5	10
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	2/665	29/18722	0.275463410296619	0.489297051170193	ZFP36/TOB1	2
GO:0000305	response to oxygen radical	2/665	29/18722	0.275463410296619	0.489297051170193	SOD2/CD36	2
GO:0001773	myeloid dendritic cell activation	2/665	29/18722	0.275463410296619	0.489297051170193	PYCARD/SPI1	2
GO:0006734	NADH metabolic process	2/665	29/18722	0.275463410296619	0.489297051170193	HK2/ENO1	2
GO:0009218	pyrimidine ribonucleotide metabolic process	2/665	29/18722	0.275463410296619	0.489297051170193	UPP1/CMPK1	2
GO:0009310	amine catabolic process	2/665	29/18722	0.275463410296619	0.489297051170193	IL4I1/KMO	2
GO:0021772	olfactory bulb development	2/665	29/18722	0.275463410296619	0.489297051170193	ATF5/LRRK2	2
GO:0022011	myelination in peripheral nervous system	2/665	29/18722	0.275463410296619	0.489297051170193	NDRG1/PLEC	2
GO:0032292	peripheral nervous system axon ensheathment	2/665	29/18722	0.275463410296619	0.489297051170193	NDRG1/PLEC	2
GO:0032366	intracellular sterol transport	2/665	29/18722	0.275463410296619	0.489297051170193	PIP4K2A/ANXA2	2
GO:0032367	intracellular cholesterol transport	2/665	29/18722	0.275463410296619	0.489297051170193	PIP4K2A/ANXA2	2
GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	2/665	29/18722	0.275463410296619	0.489297051170193	CCNY/EGFR	2
GO:0048753	pigment granule organization	2/665	29/18722	0.275463410296619	0.489297051170193	BLOC1S1/BLOC1S2	2
GO:0060969	negative regulation of gene silencing	2/665	29/18722	0.275463410296619	0.489297051170193	HIF1A-AS2/ELAVL1	2
GO:0062098	regulation of programmed necrotic cell death	2/665	29/18722	0.275463410296619	0.489297051170193	NUPR1/YBX3	2
GO:0070979	protein K11-linked ubiquitination	2/665	29/18722	0.275463410296619	0.489297051170193	UBE2B/ANAPC13	2
GO:0072539	T-helper 17 cell differentiation	2/665	29/18722	0.275463410296619	0.489297051170193	NFKBIZ/SMAD7	2
GO:0090025	regulation of monocyte chemotaxis	2/665	29/18722	0.275463410296619	0.489297051170193	DUSP1/CXCL12	2
GO:1901017	negative regulation of potassium ion transmembrane transporter activity	2/665	29/18722	0.275463410296619	0.489297051170193	PTEN/KCNE1	2
GO:2001032	regulation of double-strand break repair via nonhomologous end joining	2/665	29/18722	0.275463410296619	0.489297051170193	DTX3L/PARP9	2
GO:0003300	cardiac muscle hypertrophy	5/665	99/18722	0.275706859673675	0.489554516819637	ERRFI1/HAMP/RGS2/LMNA/JARID2	5
GO:0006278	RNA-dependent DNA biosynthetic process	4/665	75/18722	0.27644309488073	0.489986512680894	TERF2IP/NOP10/PTGES3/HNRNPA1	4
GO:0008088	axo-dendritic transport	4/665	75/18722	0.27644309488073	0.489986512680894	BLOC1S1/BLOC1S2/DST/KIF5B	4
GO:0036465	synaptic vesicle recycling	4/665	75/18722	0.27644309488073	0.489986512680894	CALM1/FCHO2/LRRK2/CALM3	4
GO:0043627	response to estrogen	4/665	75/18722	0.27644309488073	0.489986512680894	LDHA/CITED2/HMOX1/MMP14	4
GO:0051453	regulation of intracellular pH	4/665	75/18722	0.27644309488073	0.489986512680894	SLC11A1/RAB20/LRRK2/GRN	4
GO:0050769	positive regulation of neurogenesis	10/665	225/18722	0.279285760405379	0.494848566564967	CXCR4/VEGFA/TSPO/SKIL/EGFR/EPHB2/FN1/TLR2/CXCL12/NRP1	10
GO:0002218	activation of innate immune response	3/665	52/18722	0.281146854337307	0.497791188477527	CLEC7A/PYCARD/TYROBP	3
GO:0035176	social behavior	3/665	52/18722	0.281146854337307	0.497791188477527	TREM2/PTEN/VPS13A	3
GO:0045216	cell-cell junction organization	9/665	200/18722	0.281707435453618	0.49860610904718	VEGFA/CD9/LIMS1/FLNA/RHOA/PLEC/RHOC/RAB13/SMAD7	9
GO:0051588	regulation of neurotransmitter transport	5/665	100/18722	0.282574628579305	0.499607223066221	CALM1/RAP1A/LRRK2/CALM3/KMO	5
GO:0061640	cytoskeleton-dependent cytokinesis	5/665	100/18722	0.282574628579305	0.499607223066221	RHOA/RHOB/PLEC/RHOC/CHMP5	5
GO:0110020	regulation of actomyosin structure organization	5/665	100/18722	0.282574628579305	0.499607223066221	S100A10/RAC1/RHOA/RHOC/NRP1	5
GO:0001937	negative regulation of endothelial cell proliferation	4/665	76/18722	0.284408037935652	0.50213426235886	APOE/STAT1/ALOX5/ACVRL1	4
GO:0009123	nucleoside monophosphate metabolic process	4/665	76/18722	0.284408037935652	0.50213426235886	TYMP/UPP1/CMPK1/GUK1	4
GO:0014823	response to activity	4/665	76/18722	0.284408037935652	0.50213426235886	CXCR4/SOD2/SCO2/PTEN	4
GO:0086001	cardiac muscle cell action potential	4/665	76/18722	0.284408037935652	0.50213426235886	CALM1/FLNA/KCNE1/CALM3	4
GO:0055007	cardiac muscle cell differentiation	6/665	125/18722	0.284751190112936	0.502383178864498	VEGFA/HAMP/RGS2/LMNA/PLEC/CACYBP	6
GO:2000027	regulation of animal organ morphogenesis	6/665	125/18722	0.284751190112936	0.502383178864498	VEGFA/DAB2/SMURF2/CITED2/RAC1/RHOA	6
GO:0061448	connective tissue development	11/665	252/18722	0.285060563284037	0.502750532122663	SULF2/TIMP1/CRIP1/ECM1/CD44/EGR1/ARRDC3/SPI1/ACVRL1/TGFBI/SMAD7	11
GO:0051054	positive regulation of DNA metabolic process	9/665	201/18722	0.286509662288752	0.504805166597804	KLF4/UBE2B/DTX3L/PARP9/PTGES3/EGFR/HNRNPA1/PTK2B/TFRC	9
GO:0098657	import into cell	10/665	227/18722	0.288312202934793	0.504805166597804	TREM2/SLC2A5/SLC1A3/ACSL1/CD36/IRS2/SLC2A3/RGS2/WNK1/PRNP	10
GO:0003299	muscle hypertrophy in response to stress	2/665	30/18722	0.288764806566913	0.504805166597804	ERRFI1/LMNA	2
GO:0006221	pyrimidine nucleotide biosynthetic process	2/665	30/18722	0.288764806566913	0.504805166597804	UPP1/CMPK1	2
GO:0007176	regulation of epidermal growth factor-activated receptor activity	2/665	30/18722	0.288764806566913	0.504805166597804	ERRFI1/NCF1	2
GO:0009072	aromatic amino acid family metabolic process	2/665	30/18722	0.288764806566913	0.504805166597804	IL4I1/KMO	2
GO:0009264	deoxyribonucleotide catabolic process	2/665	30/18722	0.288764806566913	0.504805166597804	TYMP/UPP1	2
GO:0014887	cardiac muscle adaptation	2/665	30/18722	0.288764806566913	0.504805166597804	ERRFI1/LMNA	2
GO:0014898	cardiac muscle hypertrophy in response to stress	2/665	30/18722	0.288764806566913	0.504805166597804	ERRFI1/LMNA	2
GO:0017145	stem cell division	2/665	30/18722	0.288764806566913	0.504805166597804	ZFP36L2/EVI2B	2
GO:0032480	negative regulation of type I interferon production	2/665	30/18722	0.288764806566913	0.504805166597804	NMI/PYCARD	2
GO:0034368	protein-lipid complex remodeling	2/665	30/18722	0.288764806566913	0.504805166597804	APOE/APOC1	2
GO:0034369	plasma lipoprotein particle remodeling	2/665	30/18722	0.288764806566913	0.504805166597804	APOE/APOC1	2
GO:0036258	multivesicular body assembly	2/665	30/18722	0.288764806566913	0.504805166597804	VTA1/CHMP5	2
GO:0043304	regulation of mast cell degranulation	2/665	30/18722	0.288764806566913	0.504805166597804	CD300A/HMOX1	2
GO:0044030	regulation of DNA methylation	2/665	30/18722	0.288764806566913	0.504805166597804	SPI1/KDM1B	2
GO:0045939	negative regulation of steroid metabolic process	2/665	30/18722	0.288764806566913	0.504805166597804	APOE/INSIG2	2
GO:0048799	animal organ maturation	2/665	30/18722	0.288764806566913	0.504805166597804	SNX10/RHOA	2
GO:0051125	regulation of actin nucleation	2/665	30/18722	0.288764806566913	0.504805166597804	GSN/GMFG	2
GO:0060292	long-term synaptic depression	2/665	30/18722	0.288764806566913	0.504805166597804	PTEN/PTK2B	2
GO:0060674	placenta blood vessel development	2/665	30/18722	0.288764806566913	0.504805166597804	JUNB/SOCS3	2
GO:0070498	interleukin-1-mediated signaling pathway	2/665	30/18722	0.288764806566913	0.504805166597804	MYD88/EGR1	2
GO:0090314	positive regulation of protein targeting to membrane	2/665	30/18722	0.288764806566913	0.504805166597804	ITGAM/PRNP	2
GO:0140058	neuron projection arborization	2/665	30/18722	0.288764806566913	0.504805166597804	LRRK2/NRP1	2
GO:2000637	positive regulation of gene silencing by miRNA	2/665	30/18722	0.288764806566913	0.504805166597804	ZFP36/EGFR	2
GO:0008654	phospholipid biosynthetic process	11/665	253/18722	0.289346601947727	0.505644378227919	CAPN2/PLSCR1/PIP4K2A/IDH1/PTEN/SOCS3/SERINC1/AGPAT2/PIK3CB/HEXB/ABHD5	11
GO:0051963	regulation of synapse assembly	5/665	101/18722	0.289475005434355	0.505690958526799	IL1RAP/ABI3/EPHB2/TLR2/AGRN	5
GO:0071333	cellular response to glucose stimulus	7/665	151/18722	0.290412921164984	0.507125295279078	HLA-DRB1/TREM2/LGALS1/DYNLL1/IRS2/RAC1/KIF5B	7
GO:0007566	embryo implantation	3/665	53/18722	0.290900422066132	0.507125295279078	VEGFA/TIMP1/SMURF2	3
GO:0031279	regulation of cyclase activity	3/665	53/18722	0.290900422066132	0.507125295279078	CALM1/CALM3/CAP1	3
GO:0032784	regulation of DNA-templated transcription, elongation	3/665	53/18722	0.290900422066132	0.507125295279078	LARP7/EAF1/EAPP	3
GO:1990090	cellular response to nerve growth factor stimulus	3/665	53/18722	0.290900422066132	0.507125295279078	RAP1A/PTEN/RAPGEF1	3
GO:0031929	TOR signaling	6/665	126/18722	0.290908293126892	0.507125295279078	TREM2/DDIT4/EIF4EBP1/LAMTOR5/RRAGD/AKT1S1	6
GO:0010827	regulation of glucose transmembrane transport	4/665	77/18722	0.292406346775662	0.508803466341497	HK2/IRS2/RAP1A/PEA15	4
GO:0140056	organelle localization by membrane tethering	4/665	77/18722	0.292406346775662	0.508803466341497	CALM1/RAB8A/STX3/RAB13	4
GO:0008643	carbohydrate transport	7/665	152/18722	0.296037354733398	0.508803466341497	SLC2A5/HK2/IRS2/RAP1A/PEA15/SLC2A3/PPBP	7
GO:0031056	regulation of histone modification	7/665	152/18722	0.296037354733398	0.508803466341497	VEGFA/UBE2B/LMNA/LRRK2/SPI1/IGF2/JARID2	7
GO:0090501	RNA phosphodiester bond hydrolysis	7/665	152/18722	0.296037354733398	0.508803466341497	RNASE6/RNASET2/ANG/N4BP1/RPP30/RNASE1/HELZ2	7
GO:0001841	neural tube formation	5/665	102/18722	0.296405272358378	0.508803466341497	ADM/ST14/CITED2/RALA/SETD2	5
GO:0014897	striated muscle hypertrophy	5/665	102/18722	0.296405272358378	0.508803466341497	ERRFI1/HAMP/RGS2/LMNA/JARID2	5
GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	4/665	78/18722	0.300433860952901	0.508803466341497	RGS1/FLNA/RGS2/PSAP	4
GO:0090559	regulation of membrane permeability	4/665	78/18722	0.300433860952901	0.508803466341497	HK2/BNIP3L/BNIP3/BLOC1S2	4
GO:1901616	organic hydroxy compound catabolic process	4/665	78/18722	0.300433860952901	0.508803466341497	APOE/TPI1/ALDH2/PTEN	4
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	3/665	54/18722	0.30067705942651	0.508803466341497	VEGFA/HMOX1/ACVRL1	3
GO:0006584	catecholamine metabolic process	3/665	54/18722	0.30067705942651	0.508803466341497	NR4A2/LY6E/ITGAM	3
GO:0007215	glutamate receptor signaling pathway	3/665	54/18722	0.30067705942651	0.508803466341497	GNAQ/PTK2B/PRNP	3
GO:0009712	catechol-containing compound metabolic process	3/665	54/18722	0.30067705942651	0.508803466341497	NR4A2/LY6E/ITGAM	3
GO:0014888	striated muscle adaptation	3/665	54/18722	0.30067705942651	0.508803466341497	ERRFI1/GSN/LMNA	3
GO:0043647	inositol phosphate metabolic process	3/665	54/18722	0.30067705942651	0.508803466341497	PTEN/PTAFR/PTK2B	3
GO:0051703	biological process involved in intraspecies interaction between organisms	3/665	54/18722	0.30067705942651	0.508803466341497	TREM2/PTEN/VPS13A	3
GO:0072698	protein localization to microtubule cytoskeleton	3/665	54/18722	0.30067705942651	0.508803466341497	SNX10/MAPRE1/DIAPH1	3
GO:0006779	porphyrin-containing compound biosynthetic process	2/665	31/18722	0.302036806022174	0.508803466341497	TSPO/UROD	2
GO:0021988	olfactory lobe development	2/665	31/18722	0.302036806022174	0.508803466341497	ATF5/LRRK2	2
GO:0031063	regulation of histone deacetylation	2/665	31/18722	0.302036806022174	0.508803466341497	VEGFA/LRRK2	2
GO:0032148	activation of protein kinase B activity	2/665	31/18722	0.302036806022174	0.508803466341497	ANG/TXN	2
GO:0032509	endosome transport via multivesicular body sorting pathway	2/665	31/18722	0.302036806022174	0.508803466341497	VTA1/CHMP5	2
GO:0033006	regulation of mast cell activation involved in immune response	2/665	31/18722	0.302036806022174	0.508803466341497	CD300A/HMOX1	2
GO:0033014	tetrapyrrole biosynthetic process	2/665	31/18722	0.302036806022174	0.508803466341497	TSPO/UROD	2
GO:0033238	regulation of cellular amine metabolic process	2/665	31/18722	0.302036806022174	0.508803466341497	NR4A2/ITGAM	2
GO:0036257	multivesicular body organization	2/665	31/18722	0.302036806022174	0.508803466341497	VTA1/CHMP5	2
GO:0036474	cell death in response to hydrogen peroxide	2/665	31/18722	0.302036806022174	0.508803466341497	LRRK2/TXN	2
GO:0036475	neuron death in response to oxidative stress	2/665	31/18722	0.302036806022174	0.508803466341497	TREM2/MCL1	2
GO:0043171	peptide catabolic process	2/665	31/18722	0.302036806022174	0.508803466341497	CTSH/ANPEP	2
GO:0045987	positive regulation of smooth muscle contraction	2/665	31/18722	0.302036806022174	0.508803466341497	RHOA/PTAFR	2
GO:0046386	deoxyribose phosphate catabolic process	2/665	31/18722	0.302036806022174	0.508803466341497	TYMP/UPP1	2
GO:0048384	retinoic acid receptor signaling pathway	2/665	31/18722	0.302036806022174	0.508803466341497	KLF2/DHRS3	2
GO:0051443	positive regulation of ubiquitin-protein transferase activity	2/665	31/18722	0.302036806022174	0.508803466341497	PTEN/ARRDC3	2
GO:0060148	positive regulation of posttranscriptional gene silencing	2/665	31/18722	0.302036806022174	0.508803466341497	ZFP36/EGFR	2
GO:0060390	regulation of SMAD protein signal transduction	2/665	31/18722	0.302036806022174	0.508803466341497	DAB2/TOB1	2
GO:0061099	negative regulation of protein tyrosine kinase activity	2/665	31/18722	0.302036806022174	0.508803466341497	SH3BP5/ERRFI1	2
GO:0070528	protein kinase C signaling	2/665	31/18722	0.302036806022174	0.508803466341497	VEGFA/MYADM	2
GO:0071480	cellular response to gamma radiation	2/665	31/18722	0.302036806022174	0.508803466341497	EGR1/CDKN1A	2
GO:0090162	establishment of epithelial cell polarity	2/665	31/18722	0.302036806022174	0.508803466341497	MSN/RHOA	2
GO:0090183	regulation of kidney development	2/665	31/18722	0.302036806022174	0.508803466341497	VEGFA/STAT1	2
GO:2000144	positive regulation of DNA-templated transcription, initiation	2/665	31/18722	0.302036806022174	0.508803466341497	JUN/PSMC6	2
GO:0035303	regulation of dephosphorylation	6/665	128/18722	0.303302233926828	0.508803466341497	CD300A/CALM1/CSNK2B/PPP1R15A/LGALS3/CALM3	6
GO:0014013	regulation of gliogenesis	5/665	103/18722	0.30336273228925	0.508803466341497	CXCR4/TREM2/TSPO/EGFR/TLR2	5
GO:0000338	protein deneddylation	1/665	10/18722	0.303541705775159	0.508803466341497	COPS2	1
GO:0005984	disaccharide metabolic process	1/665	10/18722	0.303541705775159	0.508803466341497	FBP1	1
GO:0006012	galactose metabolic process	1/665	10/18722	0.303541705775159	0.508803466341497	GALK1	1
GO:0007028	cytoplasm organization	1/665	10/18722	0.303541705775159	0.508803466341497	KIF5B	1
GO:0009170	purine deoxyribonucleoside monophosphate metabolic process	1/665	10/18722	0.303541705775159	0.508803466341497	GUK1	1
GO:0010728	regulation of hydrogen peroxide biosynthetic process	1/665	10/18722	0.303541705775159	0.508803466341497	SOD2	1
GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation	1/665	10/18722	0.303541705775159	0.508803466341497	EIF2AK2	1
GO:0014041	regulation of neuron maturation	1/665	10/18722	0.303541705775159	0.508803466341497	LRRK2	1
GO:0019062	virion attachment to host cell	1/665	10/18722	0.303541705775159	0.508803466341497	CD81	1
GO:0021562	vestibulocochlear nerve development	1/665	10/18722	0.303541705775159	0.508803466341497	NRP1	1
GO:0021932	hindbrain radial glia guided cell migration	1/665	10/18722	0.303541705775159	0.508803466341497	FLNA	1
GO:0030214	hyaluronan catabolic process	1/665	10/18722	0.303541705775159	0.508803466341497	CD44	1
GO:0031118	rRNA pseudouridine synthesis	1/665	10/18722	0.303541705775159	0.508803466341497	NOP10	1
GO:0031642	negative regulation of myelination	1/665	10/18722	0.303541705775159	0.508803466341497	PTEN	1
GO:0031848	protection from non-homologous end joining at telomere	1/665	10/18722	0.303541705775159	0.508803466341497	TERF2IP	1
GO:0031915	positive regulation of synaptic plasticity	1/665	10/18722	0.303541705775159	0.508803466341497	EPHB2	1
GO:0032025	response to cobalt ion	1/665	10/18722	0.303541705775159	0.508803466341497	BNIP3	1
GO:0032275	luteinizing hormone secretion	1/665	10/18722	0.303541705775159	0.508803466341497	CGA	1
GO:0032380	regulation of intracellular sterol transport	1/665	10/18722	0.303541705775159	0.508803466341497	ANXA2	1
GO:0032383	regulation of intracellular cholesterol transport	1/665	10/18722	0.303541705775159	0.508803466341497	ANXA2	1
GO:0033572	transferrin transport	1/665	10/18722	0.303541705775159	0.508803466341497	TFRC	1
GO:0034085	establishment of sister chromatid cohesion	1/665	10/18722	0.303541705775159	0.508803466341497	RB1	1
GO:0035376	sterol import	1/665	10/18722	0.303541705775159	0.508803466341497	CD36	1
GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	1/665	10/18722	0.303541705775159	0.508803466341497	SULF2	1
GO:0035871	protein K11-linked deubiquitination	1/665	10/18722	0.303541705775159	0.508803466341497	TNFAIP3	1
GO:0035907	dorsal aorta development	1/665	10/18722	0.303541705775159	0.508803466341497	ACVRL1	1
GO:0042711	maternal behavior	1/665	10/18722	0.303541705775159	0.508803466341497	PTEN	1
GO:0042996	regulation of Golgi to plasma membrane protein transport	1/665	10/18722	0.303541705775159	0.508803466341497	ATP2C1	1
GO:0044351	macropinocytosis	1/665	10/18722	0.303541705775159	0.508803466341497	PYCARD	1
GO:0045843	negative regulation of striated muscle tissue development	1/665	10/18722	0.303541705775159	0.508803466341497	YBX3	1
GO:0045898	regulation of RNA polymerase II transcription preinitiation complex assembly	1/665	10/18722	0.303541705775159	0.508803466341497	PSMC6	1
GO:0048241	epinephrine transport	1/665	10/18722	0.303541705775159	0.508803466341497	LY6E	1
GO:0048262	determination of dorsal/ventral asymmetry	1/665	10/18722	0.303541705775159	0.508803466341497	AIDA	1
GO:0048755	branching morphogenesis of a nerve	1/665	10/18722	0.303541705775159	0.508803466341497	LRRK2	1
GO:0050861	positive regulation of B cell receptor signaling pathway	1/665	10/18722	0.303541705775159	0.508803466341497	CD81	1
GO:0051006	positive regulation of lipoprotein lipase activity	1/665	10/18722	0.303541705775159	0.508803466341497	ABHD5	1
GO:0051409	response to nitrosative stress	1/665	10/18722	0.303541705775159	0.508803466341497	DUSP6	1
GO:0060068	vagina development	1/665	10/18722	0.303541705775159	0.508803466341497	MERTK	1
GO:0060947	cardiac vascular smooth muscle cell differentiation	1/665	10/18722	0.303541705775159	0.508803466341497	VEGFA	1
GO:0070099	regulation of chemokine-mediated signaling pathway	1/665	10/18722	0.303541705775159	0.508803466341497	TREM2	1
GO:0070508	cholesterol import	1/665	10/18722	0.303541705775159	0.508803466341497	CD36	1
GO:0071073	positive regulation of phospholipid biosynthetic process	1/665	10/18722	0.303541705775159	0.508803466341497	CAPN2	1
GO:0071233	cellular response to leucine	1/665	10/18722	0.303541705775159	0.508803466341497	RRAGD	1
GO:0071838	cell proliferation in bone marrow	1/665	10/18722	0.303541705775159	0.508803466341497	MAP3K3	1
GO:0072124	regulation of glomerular mesangial cell proliferation	1/665	10/18722	0.303541705775159	0.508803466341497	EGR1	1
GO:0090037	positive regulation of protein kinase C signaling	1/665	10/18722	0.303541705775159	0.508803466341497	VEGFA	1
GO:0090209	negative regulation of triglyceride metabolic process	1/665	10/18722	0.303541705775159	0.508803466341497	APOE	1
GO:0090527	actin filament reorganization	1/665	10/18722	0.303541705775159	0.508803466341497	GSN	1
GO:0097105	presynaptic membrane assembly	1/665	10/18722	0.303541705775159	0.508803466341497	PTEN	1
GO:0098885	modification of postsynaptic actin cytoskeleton	1/665	10/18722	0.303541705775159	0.508803466341497	RHOA	1
GO:0098903	regulation of membrane repolarization during action potential	1/665	10/18722	0.303541705775159	0.508803466341497	FLNA	1
GO:0099639	neurotransmitter receptor transport, endosome to plasma membrane	1/665	10/18722	0.303541705775159	0.508803466341497	RAB8A	1
GO:0140059	dendrite arborization	1/665	10/18722	0.303541705775159	0.508803466341497	NRP1	1
GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	1/665	10/18722	0.303541705775159	0.508803466341497	NCL	1
GO:1902023	L-arginine transport	1/665	10/18722	0.303541705775159	0.508803466341497	SLC11A1	1
GO:1904350	regulation of protein catabolic process in the vacuole	1/665	10/18722	0.303541705775159	0.508803466341497	CD81	1
GO:1904668	positive regulation of ubiquitin protein ligase activity	1/665	10/18722	0.303541705775159	0.508803466341497	PTEN	1
GO:1905383	protein localization to presynapse	1/665	10/18722	0.303541705775159	0.508803466341497	KIF5B	1
GO:1905456	regulation of lymphoid progenitor cell differentiation	1/665	10/18722	0.303541705775159	0.508803466341497	SOS2	1
GO:1905809	negative regulation of synapse organization	1/665	10/18722	0.303541705775159	0.508803466341497	TLR2	1
GO:1905941	positive regulation of gonad development	1/665	10/18722	0.303541705775159	0.508803466341497	CITED2	1
GO:1990253	cellular response to leucine starvation	1/665	10/18722	0.303541705775159	0.508803466341497	RRAGD	1
GO:1990535	neuron projection maintenance	1/665	10/18722	0.303541705775159	0.508803466341497	PRNP	1
GO:2000018	regulation of male gonad development	1/665	10/18722	0.303541705775159	0.508803466341497	CITED2	1
GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin	1/665	10/18722	0.303541705775159	0.508803466341497	VEGFA	1
GO:2000121	regulation of removal of superoxide radicals	1/665	10/18722	0.303541705775159	0.508803466341497	CD36	1
GO:2000169	regulation of peptidyl-cysteine S-nitrosylation	1/665	10/18722	0.303541705775159	0.508803466341497	TXN	1
GO:2000425	regulation of apoptotic cell clearance	1/665	10/18722	0.303541705775159	0.508803466341497	TREM2	1
GO:2000510	positive regulation of dendritic cell chemotaxis	1/665	10/18722	0.303541705775159	0.508803466341497	SPI1	1
GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	1/665	10/18722	0.303541705775159	0.508803466341497	GSN	1
GO:0007416	synapse assembly	8/665	179/18722	0.304417899512902	0.510100121570844	IL1RAP/PTEN/GABRB2/SDCBP/ABI3/EPHB2/TLR2/AGRN	8
GO:0006022	aminoglycan metabolic process	6/665	129/18722	0.309535254791361	0.518500241426716	CD44/IDS/LYVE1/B3GNT7/CHST15/HEXB	6
GO:0014896	muscle hypertrophy	5/665	104/18722	0.310344711357307	0.518841412197543	ERRFI1/HAMP/RGS2/LMNA/JARID2	5
GO:0032006	regulation of TOR signaling	5/665	104/18722	0.310344711357307	0.518841412197543	TREM2/DDIT4/LAMTOR5/RRAGD/AKT1S1	5
GO:0032963	collagen metabolic process	5/665	104/18722	0.310344711357307	0.518841412197543	VIM/ERRFI1/RAP1A/MMP19/MMP14	5
GO:0008333	endosome to lysosome transport	3/665	55/18722	0.310469690115793	0.518841412197543	DTX3L/RHOB/CHMP5	3
GO:0010676	positive regulation of cellular carbohydrate metabolic process	3/665	55/18722	0.310469690115793	0.518841412197543	IRS2/PTAFR/IGF2	3
GO:0051898	negative regulation of protein kinase B signaling	3/665	55/18722	0.310469690115793	0.518841412197543	KLF4/PTEN/PIK3CB	3
GO:1902991	regulation of amyloid precursor protein catabolic process	3/665	55/18722	0.310469690115793	0.518841412197543	APOE/RTN3/PRNP	3
GO:0042593	glucose homeostasis	11/665	258/18722	0.311039594549353	0.519619087364801	HLA-DRB1/TREM2/LGALS1/OAS1/ALOX5/HK2/DYNLL1/IRS2/RAC1/GPI/KIF5B	11
GO:0051960	regulation of nervous system development	18/665	443/18722	0.312570242749215	0.519847739708292	CXCR4/TREM2/VEGFA/B2M/YWHAH/TYMP/IL1RAP/TSPO/BHLHE40/SKIL/PTEN/EGFR/EPHB2/FN1/TLR2/AGRN/CXCL12/NRP1	18
GO:1901987	regulation of cell cycle phase transition	16/665	390/18722	0.312844392479675	0.519847739708292	ATF5/GPNMB/DUSP1/ZFP36L2/KLF4/PSME2/RPS27L/PTEN/ANXA1/EGFR/RPA2/PLK3/CDKN1A/FOXN3/RB1/XPC	16
GO:0046434	organophosphate catabolic process	7/665	155/18722	0.3130468647354	0.519847739708292	APOC1/TYMP/UPP1/IDH1/PTEN/GPCPD1/PLBD1	7
GO:0051147	regulation of muscle cell differentiation	7/665	155/18722	0.3130468647354	0.519847739708292	SOD2/HAMP/RGS2/YBX1/MMP14/CAMK1/IGF2	7
GO:0050767	regulation of neurogenesis	15/665	364/18722	0.314536368860089	0.519847739708292	CXCR4/TREM2/VEGFA/B2M/YWHAH/TSPO/BHLHE40/SKIL/PTEN/EGFR/EPHB2/FN1/TLR2/CXCL12/NRP1	15
GO:0010644	cell communication by electrical coupling	2/665	32/18722	0.315264733530176	0.519847739708292	CALM1/CALM3	2
GO:0014044	Schwann cell development	2/665	32/18722	0.315264733530176	0.519847739708292	NDRG1/PLEC	2
GO:0019835	cytolysis	2/665	32/18722	0.315264733530176	0.519847739708292	LYZ/MMD	2
GO:0034367	protein-containing complex remodeling	2/665	32/18722	0.315264733530176	0.519847739708292	APOE/APOC1	2
GO:0042744	hydrogen peroxide catabolic process	2/665	32/18722	0.315264733530176	0.519847739708292	HBG1/GPX1	2
GO:0046475	glycerophospholipid catabolic process	2/665	32/18722	0.315264733530176	0.519847739708292	APOC1/GPCPD1	2
GO:0050850	positive regulation of calcium-mediated signaling	2/665	32/18722	0.315264733530176	0.519847739708292	TREM2/CLEC7A	2
GO:0061036	positive regulation of cartilage development	2/665	32/18722	0.315264733530176	0.519847739708292	ACVRL1/SMAD7	2
GO:0071875	adrenergic receptor signaling pathway	2/665	32/18722	0.315264733530176	0.519847739708292	RGS2/ARRDC3	2
GO:0072337	modified amino acid transport	2/665	32/18722	0.315264733530176	0.519847739708292	SLC6A8/SLC38A2	2
GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	2/665	32/18722	0.315264733530176	0.519847739708292	LRRK2/GRINA	2
GO:2000191	regulation of fatty acid transport	2/665	32/18722	0.315264733530176	0.519847739708292	ACSL1/IRS2	2
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	2/665	32/18722	0.315264733530176	0.519847739708292	ANXA1/SMAD7	2
GO:0033500	carbohydrate homeostasis	11/665	259/18722	0.315426306248093	0.519847739708292	HLA-DRB1/TREM2/LGALS1/OAS1/ALOX5/HK2/DYNLL1/IRS2/RAC1/GPI/KIF5B	11
GO:0006282	regulation of DNA repair	6/665	130/18722	0.315789779346997	0.519847739708292	TERF2IP/DTX3L/PARP9/EGFR/RPA2/SETD2	6
GO:0007422	peripheral nervous system development	4/665	80/18722	0.316560196193332	0.519847739708292	NDRG1/CITED2/PLEC/ALDH3A2	4
GO:1901264	carbohydrate derivative transport	4/665	80/18722	0.316560196193332	0.519847739708292	SLC25A19/ABCC3/GUK1/PSAP	4
GO:0016079	synaptic vesicle exocytosis	5/665	105/18722	0.317348561142909	0.519847739708292	CALM1/RAP1A/LRRK2/CALM3/STX3	5
GO:2001022	positive regulation of response to DNA damage stimulus	5/665	105/18722	0.317348561142909	0.519847739708292	SKIL/DTX3L/PARP9/EGFR/ZNF385A	5
GO:0046486	glycerolipid metabolic process	16/665	392/18722	0.319989387624528	0.519847739708292	APOE/CAPN2/APOC1/PLSCR1/ACSL1/ANG/PIP4K2A/PTEN/SOCS3/GPCPD1/SERINC1/INSIG2/AGPAT2/PIK3CB/ABHD5/GPX1	16
GO:0051260	protein homooligomerization	8/665	182/18722	0.320213956563624	0.519847739708292	B2M/ALDOA/SOD2/MIF/PYCARD/ALOX5AP/ELAVL1/PRNP	8
GO:0061138	morphogenesis of a branching epithelium	8/665	182/18722	0.320213956563624	0.519847739708292	VEGFA/CTSH/ADM/ST14/GRB2/SOCS3/MMP14/NRP1	8
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	3/665	56/18722	0.32027146658929	0.519847739708292	ZFP36L2/ZFP36/TOB1	3
GO:0002090	regulation of receptor internalization	3/665	56/18722	0.32027146658929	0.519847739708292	VEGFA/RIN3/SDCBP	3
GO:0010332	response to gamma radiation	3/665	56/18722	0.32027146658929	0.519847739708292	EGR1/CDKN1A/GPX1	3
GO:0031122	cytoplasmic microtubule organization	3/665	56/18722	0.32027146658929	0.519847739708292	RHOA/DST/PLK3	3
GO:0031529	ruffle organization	3/665	56/18722	0.32027146658929	0.519847739708292	SNX10/RAC1/ABI3	3
GO:0046622	positive regulation of organ growth	3/665	56/18722	0.32027146658929	0.519847739708292	YBX3/HAMP/IGF2	3
GO:0051058	negative regulation of small GTPase mediated signal transduction	3/665	56/18722	0.32027146658929	0.519847739708292	FBP1/PPP2CB/EPHB2	3
GO:1990089	response to nerve growth factor	3/665	56/18722	0.32027146658929	0.519847739708292	RAP1A/PTEN/RAPGEF1	3
GO:0045787	positive regulation of cell cycle	13/665	313/18722	0.321579596486231	0.519847739708292	NUPR1/PLSCR1/UBE2B/CITED2/CCNY/ANXA1/EIF4EBP1/RHOA/EGFR/DYNLT3/IGF2/RB1/EIF4E	13
GO:0090305	nucleic acid phosphodiester bond hydrolysis	11/665	261/18722	0.324242724390209	0.519847739708292	RNASE6/PLSCR1/RNASET2/ZFP36/ANG/N4BP1/RPP30/RNASE1/HELZ2/PLD3/XPC	11
GO:0002062	chondrocyte differentiation	5/665	106/18722	0.324371660818659	0.519847739708292	SULF2/ECM1/ACVRL1/TGFBI/SMAD7	5
GO:0010833	telomere maintenance via telomere lengthening	4/665	81/18722	0.324651038981267	0.519847739708292	TERF2IP/NOP10/PTGES3/HNRNPA1	4
GO:0021954	central nervous system neuron development	4/665	81/18722	0.324651038981267	0.519847739708292	NR4A2/PTEN/EPHB2/NRP1	4
GO:0030641	regulation of cellular pH	4/665	81/18722	0.324651038981267	0.519847739708292	SLC11A1/RAB20/LRRK2/GRN	4
GO:0051149	positive regulation of muscle cell differentiation	4/665	81/18722	0.324651038981267	0.519847739708292	SOD2/HAMP/MMP14/CAMK1	4
GO:0060968	regulation of gene silencing	4/665	81/18722	0.324651038981267	0.519847739708292	ZFP36/HIF1A-AS2/EGFR/ELAVL1	4
GO:0001787	natural killer cell proliferation	1/665	11/18722	0.328292922409378	0.519847739708292	HLA-E	1
GO:0001867	complement activation, lectin pathway	1/665	11/18722	0.328292922409378	0.519847739708292	SERPING1	1
GO:0002732	positive regulation of dendritic cell cytokine production	1/665	11/18722	0.328292922409378	0.519847739708292	CLEC7A	1
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	1/665	11/18722	0.328292922409378	0.519847739708292	FCGR2B	1
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	1/665	11/18722	0.328292922409378	0.519847739708292	CYCS	1
GO:0006527	arginine catabolic process	1/665	11/18722	0.328292922409378	0.519847739708292	DDAH2	1
GO:0006707	cholesterol catabolic process	1/665	11/18722	0.328292922409378	0.519847739708292	APOE	1
GO:0006971	hypotonic response	1/665	11/18722	0.328292922409378	0.519847739708292	TSPO	1
GO:0007042	lysosomal lumen acidification	1/665	11/18722	0.328292922409378	0.519847739708292	GRN	1
GO:0009313	oligosaccharide catabolic process	1/665	11/18722	0.328292922409378	0.519847739708292	HEXB	1
GO:0010739	positive regulation of protein kinase A signaling	1/665	11/18722	0.328292922409378	0.519847739708292	MIF	1
GO:0010887	negative regulation of cholesterol storage	1/665	11/18722	0.328292922409378	0.519847739708292	TREM2	1
GO:0016127	sterol catabolic process	1/665	11/18722	0.328292922409378	0.519847739708292	APOE	1
GO:0018026	peptidyl-lysine monomethylation	1/665	11/18722	0.328292922409378	0.519847739708292	SETD2	1
GO:0021561	facial nerve development	1/665	11/18722	0.328292922409378	0.519847739708292	NRP1	1
GO:0021604	cranial nerve structural organization	1/665	11/18722	0.328292922409378	0.519847739708292	NRP1	1
GO:0021610	facial nerve morphogenesis	1/665	11/18722	0.328292922409378	0.519847739708292	NRP1	1
GO:0021889	olfactory bulb interneuron differentiation	1/665	11/18722	0.328292922409378	0.519847739708292	ATF5	1
GO:0032000	positive regulation of fatty acid beta-oxidation	1/665	11/18722	0.328292922409378	0.519847739708292	IRS2	1
GO:0032329	serine transport	1/665	11/18722	0.328292922409378	0.519847739708292	SLC38A2	1
GO:0032377	regulation of intracellular lipid transport	1/665	11/18722	0.328292922409378	0.519847739708292	ANXA2	1
GO:0032836	glomerular basement membrane development	1/665	11/18722	0.328292922409378	0.519847739708292	SULF2	1
GO:0033033	negative regulation of myeloid cell apoptotic process	1/665	11/18722	0.328292922409378	0.519847739708292	IRF7	1
GO:0033083	regulation of immature T cell proliferation	1/665	11/18722	0.328292922409378	0.519847739708292	RIPK2	1
GO:0033210	leptin-mediated signaling pathway	1/665	11/18722	0.328292922409378	0.519847739708292	EBI3	1
GO:0033632	regulation of cell-cell adhesion mediated by integrin	1/665	11/18722	0.328292922409378	0.519847739708292	WNK1	1
GO:0034350	regulation of glial cell apoptotic process	1/665	11/18722	0.328292922409378	0.519847739708292	TREM2	1
GO:0034975	protein folding in endoplasmic reticulum	1/665	11/18722	0.328292922409378	0.519847739708292	ERO1A	1
GO:0035090	maintenance of apical/basal cell polarity	1/665	11/18722	0.328292922409378	0.519847739708292	LIN7C	1
GO:0035581	sequestering of extracellular ligand from receptor	1/665	11/18722	0.328292922409378	0.519847739708292	FBN2	1
GO:0036490	regulation of translation in response to endoplasmic reticulum stress	1/665	11/18722	0.328292922409378	0.519847739708292	PPP1R15A	1
GO:0042167	heme catabolic process	1/665	11/18722	0.328292922409378	0.519847739708292	HMOX1	1
GO:0042416	dopamine biosynthetic process	1/665	11/18722	0.328292922409378	0.519847739708292	NR4A2	1
GO:0042447	hormone catabolic process	1/665	11/18722	0.328292922409378	0.519847739708292	HSD17B11	1
GO:0043589	skin morphogenesis	1/665	11/18722	0.328292922409378	0.519847739708292	ERRFI1	1
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	1/665	11/18722	0.328292922409378	0.519847739708292	HMOX1	1
GO:0045060	negative thymic T cell selection	1/665	11/18722	0.328292922409378	0.519847739708292	CD74	1
GO:0045161	neuronal ion channel clustering	1/665	11/18722	0.328292922409378	0.519847739708292	AGRN	1
GO:0045199	maintenance of epithelial cell apical/basal polarity	1/665	11/18722	0.328292922409378	0.519847739708292	LIN7C	1
GO:0045793	positive regulation of cell size	1/665	11/18722	0.328292922409378	0.519847739708292	TMEM123	1
GO:0046149	pigment catabolic process	1/665	11/18722	0.328292922409378	0.519847739708292	HMOX1	1
GO:0046501	protoporphyrinogen IX metabolic process	1/665	11/18722	0.328292922409378	0.519847739708292	UROD	1
GO:0046710	GDP metabolic process	1/665	11/18722	0.328292922409378	0.519847739708292	GUK1	1
GO:0046929	negative regulation of neurotransmitter secretion	1/665	11/18722	0.328292922409378	0.519847739708292	RAP1A	1
GO:0046940	nucleoside monophosphate phosphorylation	1/665	11/18722	0.328292922409378	0.519847739708292	CMPK1	1
GO:0048103	somatic stem cell division	1/665	11/18722	0.328292922409378	0.519847739708292	ZFP36L2	1
GO:0048635	negative regulation of muscle organ development	1/665	11/18722	0.328292922409378	0.519847739708292	YBX3	1
GO:0048853	forebrain morphogenesis	1/665	11/18722	0.328292922409378	0.519847739708292	PTEN	1
GO:0051132	NK T cell activation	1/665	11/18722	0.328292922409378	0.519847739708292	CD300A	1
GO:0051561	positive regulation of mitochondrial calcium ion concentration	1/665	11/18722	0.328292922409378	0.519847739708292	BNIP3	1
GO:0055015	ventricular cardiac muscle cell development	1/665	11/18722	0.328292922409378	0.519847739708292	LMNA	1
GO:0060159	regulation of dopamine receptor signaling pathway	1/665	11/18722	0.328292922409378	0.519847739708292	LRRK2	1
GO:0060742	epithelial cell differentiation involved in prostate gland development	1/665	11/18722	0.328292922409378	0.519847739708292	PSAP	1
GO:0060746	parental behavior	1/665	11/18722	0.328292922409378	0.519847739708292	PTEN	1
GO:0060837	blood vessel endothelial cell differentiation	1/665	11/18722	0.328292922409378	0.519847739708292	NRP1	1
GO:0061365	positive regulation of triglyceride lipase activity	1/665	11/18722	0.328292922409378	0.519847739708292	ABHD5	1
GO:0061635	regulation of protein complex stability	1/665	11/18722	0.328292922409378	0.519847739708292	SQSTM1	1
GO:0070189	kynurenine metabolic process	1/665	11/18722	0.328292922409378	0.519847739708292	KMO	1
GO:0070243	regulation of thymocyte apoptotic process	1/665	11/18722	0.328292922409378	0.519847739708292	ADAM8	1
GO:0070327	thyroid hormone transport	1/665	11/18722	0.328292922409378	0.519847739708292	SLC16A10	1
GO:0070341	fat cell proliferation	1/665	11/18722	0.328292922409378	0.519847739708292	TREM2	1
GO:0070344	regulation of fat cell proliferation	1/665	11/18722	0.328292922409378	0.519847739708292	TREM2	1
GO:0070417	cellular response to cold	1/665	11/18722	0.328292922409378	0.519847739708292	NFKBIA	1
GO:0070778	L-aspartate transmembrane transport	1/665	11/18722	0.328292922409378	0.519847739708292	SLC1A3	1
GO:0071044	histone mRNA catabolic process	1/665	11/18722	0.328292922409378	0.519847739708292	SSB	1
GO:0071492	cellular response to UV-A	1/665	11/18722	0.328292922409378	0.519847739708292	TIMP1	1
GO:0071609	chemokine (C-C motif) ligand 5 production	1/665	11/18722	0.328292922409378	0.519847739708292	OAS3	1
GO:0071649	regulation of chemokine (C-C motif) ligand 5 production	1/665	11/18722	0.328292922409378	0.519847739708292	OAS3	1
GO:0071888	macrophage apoptotic process	1/665	11/18722	0.328292922409378	0.519847739708292	IRF7	1
GO:0072110	glomerular mesangial cell proliferation	1/665	11/18722	0.328292922409378	0.519847739708292	EGR1	1
GO:0072497	mesenchymal stem cell differentiation	1/665	11/18722	0.328292922409378	0.519847739708292	KRT18	1
GO:0072697	protein localization to cell cortex	1/665	11/18722	0.328292922409378	0.519847739708292	EPB41	1
GO:0075522	IRES-dependent viral translational initiation	1/665	11/18722	0.328292922409378	0.519847739708292	SSB	1
GO:0090219	negative regulation of lipid kinase activity	1/665	11/18722	0.328292922409378	0.519847739708292	PIP4K2A	1
GO:0097048	dendritic cell apoptotic process	1/665	11/18722	0.328292922409378	0.519847739708292	CXCL12	1
GO:0097090	presynaptic membrane organization	1/665	11/18722	0.328292922409378	0.519847739708292	PTEN	1
GO:0097104	postsynaptic membrane assembly	1/665	11/18722	0.328292922409378	0.519847739708292	EPHB2	1
GO:0097494	regulation of vesicle size	1/665	11/18722	0.328292922409378	0.519847739708292	RIN3	1
GO:0098935	dendritic transport	1/665	11/18722	0.328292922409378	0.519847739708292	KIF5B	1
GO:0099550	trans-synaptic signaling, modulating synaptic transmission	1/665	11/18722	0.328292922409378	0.519847739708292	EPHB2	1
GO:0099624	atrial cardiac muscle cell membrane repolarization	1/665	11/18722	0.328292922409378	0.519847739708292	FLNA	1
GO:0106049	regulation of cellular response to osmotic stress	1/665	11/18722	0.328292922409378	0.519847739708292	YBX3	1
GO:0106072	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	1/665	11/18722	0.328292922409378	0.519847739708292	ARRDC3	1
GO:1900112	regulation of histone H3-K9 trimethylation	1/665	11/18722	0.328292922409378	0.519847739708292	LMNA	1
GO:1900247	regulation of cytoplasmic translational elongation	1/665	11/18722	0.328292922409378	0.519847739708292	CPEB2	1
GO:1900426	positive regulation of defense response to bacterium	1/665	11/18722	0.328292922409378	0.519847739708292	GRN	1
GO:1901862	negative regulation of muscle tissue development	1/665	11/18722	0.328292922409378	0.519847739708292	YBX3	1
GO:1902033	regulation of hematopoietic stem cell proliferation	1/665	11/18722	0.328292922409378	0.519847739708292	EIF2AK2	1
GO:1903238	positive regulation of leukocyte tethering or rolling	1/665	11/18722	0.328292922409378	0.519847739708292	PTAFR	1
GO:1903423	positive regulation of synaptic vesicle recycling	1/665	11/18722	0.328292922409378	0.519847739708292	LRRK2	1
GO:1903897	regulation of PERK-mediated unfolded protein response	1/665	11/18722	0.328292922409378	0.519847739708292	PPP1R15A	1
GO:1903961	positive regulation of anion transmembrane transport	1/665	11/18722	0.328292922409378	0.519847739708292	PTAFR	1
GO:1904181	positive regulation of membrane depolarization	1/665	11/18722	0.328292922409378	0.519847739708292	TSPO	1
GO:1904321	response to forskolin	1/665	11/18722	0.328292922409378	0.519847739708292	AHR	1
GO:1904322	cellular response to forskolin	1/665	11/18722	0.328292922409378	0.519847739708292	AHR	1
GO:1904464	regulation of matrix metallopeptidase secretion	1/665	11/18722	0.328292922409378	0.519847739708292	TLR2	1
GO:1904869	regulation of protein localization to Cajal body	1/665	11/18722	0.328292922409378	0.519847739708292	LARP7	1
GO:1904871	positive regulation of protein localization to Cajal body	1/665	11/18722	0.328292922409378	0.519847739708292	LARP7	1
GO:1905150	regulation of voltage-gated sodium channel activity	1/665	11/18722	0.328292922409378	0.519847739708292	KIF5B	1
GO:1905522	negative regulation of macrophage migration	1/665	11/18722	0.328292922409378	0.519847739708292	MIF	1
GO:1990773	matrix metallopeptidase secretion	1/665	11/18722	0.328292922409378	0.519847739708292	TLR2	1
GO:2000320	negative regulation of T-helper 17 cell differentiation	1/665	11/18722	0.328292922409378	0.519847739708292	SMAD7	1
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	1/665	11/18722	0.328292922409378	0.519847739708292	CD74	1
GO:2000668	regulation of dendritic cell apoptotic process	1/665	11/18722	0.328292922409378	0.519847739708292	CXCL12	1
GO:2000786	positive regulation of autophagosome assembly	1/665	11/18722	0.328292922409378	0.519847739708292	PIP4K2A	1
GO:0001881	receptor recycling	2/665	33/18722	0.328434990479686	0.519847739708292	ANXA2/CHMP5	2
GO:0006654	phosphatidic acid biosynthetic process	2/665	33/18722	0.328434990479686	0.519847739708292	AGPAT2/ABHD5	2
GO:0009156	ribonucleoside monophosphate biosynthetic process	2/665	33/18722	0.328434990479686	0.519847739708292	UPP1/CMPK1	2
GO:0010259	multicellular organism aging	2/665	33/18722	0.328434990479686	0.519847739708292	CISD2/LRRK2	2
GO:0031116	positive regulation of microtubule polymerization	2/665	33/18722	0.328434990479686	0.519847739708292	MAPRE1/RAC1	2
GO:0032228	regulation of synaptic transmission, GABAergic	2/665	33/18722	0.328434990479686	0.519847739708292	PTEN/KIF5B	2
GO:0045648	positive regulation of erythrocyte differentiation	2/665	33/18722	0.328434990479686	0.519847739708292	ISG15/STAT1	2
GO:0048048	embryonic eye morphogenesis	2/665	33/18722	0.328434990479686	0.519847739708292	CITED2/FBN2	2
GO:0050974	detection of mechanical stimulus involved in sensory perception	2/665	33/18722	0.328434990479686	0.519847739708292	CXCR4/CXCL12	2
GO:0071539	protein localization to centrosome	2/665	33/18722	0.328434990479686	0.519847739708292	SNX10/MAPRE1	2
GO:1900181	negative regulation of protein localization to nucleus	2/665	33/18722	0.328434990479686	0.519847739708292	CD36/MDFIC	2
GO:1901099	negative regulation of signal transduction in absence of ligand	2/665	33/18722	0.328434990479686	0.519847739708292	IFI6/MCL1	2
GO:1901380	negative regulation of potassium ion transmembrane transport	2/665	33/18722	0.328434990479686	0.519847739708292	PTEN/KCNE1	2
GO:1901976	regulation of cell cycle checkpoint	2/665	33/18722	0.328434990479686	0.519847739708292	DUSP1/RPA2	2
GO:1902692	regulation of neuroblast proliferation	2/665	33/18722	0.328434990479686	0.519847739708292	VEGFA/LRRK2	2
GO:2000036	regulation of stem cell population maintenance	2/665	33/18722	0.328434990479686	0.519847739708292	ELAVL1/ZC3H13	2
GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	2/665	33/18722	0.328434990479686	0.519847739708292	IFI6/MCL1	2
GO:0030072	peptide hormone secretion	10/665	236/18722	0.329831243096142	0.521448373745621	HLA-DRB1/ALOX5/GLUL/DYNLL1/IRS2/RAC1/ANXA1/EGFR/KIF5B/SLC16A10	10
GO:0006611	protein export from nucleus	3/665	57/18722	0.330075771389079	0.521448373745621	IFI27/TXN/CAMK1	3
GO:0006754	ATP biosynthetic process	3/665	57/18722	0.330075771389079	0.521448373745621	TREM2/ALDOA/ENO1	3
GO:0030219	megakaryocyte differentiation	3/665	57/18722	0.330075771389079	0.521448373745621	PIP4K2A/ABI1/ZNF385A	3
GO:0051289	protein homotetramerization	3/665	57/18722	0.330075771389079	0.521448373745621	B2M/ALDOA/SOD2	3
GO:0051785	positive regulation of nuclear division	3/665	57/18722	0.330075771389079	0.521448373745621	UBE2B/IGF2/RB1	3
GO:0050000	chromosome localization	4/665	82/18722	0.332755136524381	0.525347213636014	UBE2B/LMNA/CHMP5/RMDN1	4
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	4/665	82/18722	0.332755136524381	0.525347213636014	RNASET2/ANG/RPP30/RNASE1	4
GO:0006958	complement activation, classical pathway	5/665	108/18722	0.338465276549779	0.534192576834679	TREM2/SERPING1/C1QB/C1QC/C1QA	5
GO:0009161	ribonucleoside monophosphate metabolic process	3/665	58/18722	0.339876217786765	0.535738916079994	UPP1/CMPK1/GUK1	3
GO:0010574	regulation of vascular endothelial growth factor production	3/665	58/18722	0.339876217786765	0.535738916079994	SULF2/C5AR1/CYP1B1	3
GO:0044380	protein localization to cytoskeleton	3/665	58/18722	0.339876217786765	0.535738916079994	SNX10/MAPRE1/DIAPH1	3
GO:0086065	cell communication involved in cardiac conduction	3/665	58/18722	0.339876217786765	0.535738916079994	CALM1/FLNA/CALM3	3
GO:0008277	regulation of G protein-coupled receptor signaling pathway	6/665	134/18722	0.340985419655612	0.536312459767735	RGS1/CXCL8/ADM/RGS2/ARRDC3/PHB	6
GO:0001662	behavioral fear response	2/665	34/18722	0.341534997015066	0.536312459767735	APOE/EIF4E	2
GO:0006356	regulation of transcription by RNA polymerase I	2/665	34/18722	0.341534997015066	0.536312459767735	FLNA/NCL	2
GO:0007095	mitotic G2 DNA damage checkpoint signaling	2/665	34/18722	0.341534997015066	0.536312459767735	CDKN1A/FOXN3	2
GO:0009112	nucleobase metabolic process	2/665	34/18722	0.341534997015066	0.536312459767735	TYMP/CMPK1	2
GO:0035308	negative regulation of protein dephosphorylation	2/665	34/18722	0.341534997015066	0.536312459767735	PPP1R15A/LGALS3	2
GO:0035590	purinergic nucleotide receptor signaling pathway	2/665	34/18722	0.341534997015066	0.536312459767735	ADORA3/PTAFR	2
GO:0048536	spleen development	2/665	34/18722	0.341534997015066	0.536312459767735	CITED2/JARID2	2
GO:0048741	skeletal muscle fiber development	2/665	34/18722	0.341534997015066	0.536312459767735	PLEC/GPX1	2
GO:0051973	positive regulation of telomerase activity	2/665	34/18722	0.341534997015066	0.536312459767735	KLF4/PTGES3	2
GO:0070884	regulation of calcineurin-NFAT signaling cascade	2/665	34/18722	0.341534997015066	0.536312459767735	CLEC7A/PRNP	2
GO:2000352	negative regulation of endothelial cell apoptotic process	2/665	34/18722	0.341534997015066	0.536312459767735	TNFAIP3/ANGPTL4	2
GO:0035637	multicellular organismal signaling	7/665	160/18722	0.341764422782575	0.536333811565961	CALM1/TYMP/FLNA/KCNE1/PLEC/CALM3/SCN9A	7
GO:0060402	calcium ion transport into cytosol	7/665	160/18722	0.341764422782575	0.536333811565961	CALM1/ERO1A/CLIC2/CALM3/PTK2B/DIAPH1/PRNP	7
GO:0001505	regulation of neurotransmitter levels	9/665	213/18722	0.345585989902376	0.53871265390454	CALM1/SLC1A3/RAP1A/LRRK2/LIN7C/CALM3/STX3/KMO/NR4A1	9
GO:0042310	vasoconstriction	4/665	84/18722	0.348987976392758	0.53871265390454	ADM/DOCK4/RHOA/EGFR	4
GO:0048568	embryonic organ development	17/665	427/18722	0.349507254112192	0.53871265390454	VEGFA/CXCL8/CEBPB/ADM/ST14/MAFB/JUNB/GRB2/CITED2/SOCS3/FBN2/PHLDA2/INSIG2/MMP14/IGF2/EPHB2/SETD2	17
GO:0030042	actin filament depolymerization	3/665	59/18722	0.349666649797747	0.53871265390454	CAPG/GSN/CFL1	3
GO:0033013	tetrapyrrole metabolic process	3/665	59/18722	0.349666649797747	0.53871265390454	TSPO/HMOX1/UROD	3
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	3/665	59/18722	0.349666649797747	0.53871265390454	KLF4/SOCS3/PTK2B	3
GO:0048010	vascular endothelial growth factor receptor signaling pathway	3/665	59/18722	0.349666649797747	0.53871265390454	VEGFA/PTK2B/NRP1	3
GO:0048278	vesicle docking	3/665	59/18722	0.349666649797747	0.53871265390454	RAB8A/STX3/RAB13	3
GO:0051055	negative regulation of lipid biosynthetic process	3/665	59/18722	0.349666649797747	0.53871265390454	APOE/APOC1/INSIG2	3
GO:0071806	protein transmembrane transport	3/665	59/18722	0.349666649797747	0.53871265390454	MCL1/SEC61G/DNAJC15	3
GO:0044242	cellular lipid catabolic process	9/665	214/18722	0.350602218552507	0.53871265390454	APOC1/HSD17B4/IRS2/IDH1/GPCPD1/PLBD1/HEXB/CYP1B1/ABHD5	9
GO:0001976	nervous system process involved in regulation of systemic arterial blood pressure	1/665	12/18722	0.352165788990414	0.53871265390454	SOD2	1
GO:0002182	cytoplasmic translational elongation	1/665	12/18722	0.352165788990414	0.53871265390454	CPEB2	1
GO:0002328	pro-B cell differentiation	1/665	12/18722	0.352165788990414	0.53871265390454	SOS2	1
GO:0002664	regulation of T cell tolerance induction	1/665	12/18722	0.352165788990414	0.53871265390454	HLA-B	1
GO:0006068	ethanol catabolic process	1/665	12/18722	0.352165788990414	0.53871265390454	ALDH2	1
GO:0006620	posttranslational protein targeting to endoplasmic reticulum membrane	1/665	12/18722	0.352165788990414	0.53871265390454	SEC61G	1
GO:0006787	porphyrin-containing compound catabolic process	1/665	12/18722	0.352165788990414	0.53871265390454	HMOX1	1
GO:0009265	2'-deoxyribonucleotide biosynthetic process	1/665	12/18722	0.352165788990414	0.53871265390454	GUK1	1
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	1/665	12/18722	0.352165788990414	0.53871265390454	PTPN12	1
GO:0021559	trigeminal nerve development	1/665	12/18722	0.352165788990414	0.53871265390454	NRP1	1
GO:0030157	pancreatic juice secretion	1/665	12/18722	0.352165788990414	0.53871265390454	WNK1	1
GO:0031126	sno(s)RNA 3'-end processing	1/665	12/18722	0.352165788990414	0.53871265390454	LARP7	1
GO:0031223	auditory behavior	1/665	12/18722	0.352165788990414	0.53871265390454	SLC1A3	1
GO:0031953	negative regulation of protein autophosphorylation	1/665	12/18722	0.352165788990414	0.53871265390454	ERRFI1	1
GO:0032621	interleukin-18 production	1/665	12/18722	0.352165788990414	0.53871265390454	TLR2	1
GO:0032661	regulation of interleukin-18 production	1/665	12/18722	0.352165788990414	0.53871265390454	TLR2	1
GO:0032908	regulation of transforming growth factor beta1 production	1/665	12/18722	0.352165788990414	0.53871265390454	TYROBP	1
GO:0033015	tetrapyrrole catabolic process	1/665	12/18722	0.352165788990414	0.53871265390454	HMOX1	1
GO:0033079	immature T cell proliferation	1/665	12/18722	0.352165788990414	0.53871265390454	RIPK2	1
GO:0033127	regulation of histone phosphorylation	1/665	12/18722	0.352165788990414	0.53871265390454	UBE2B	1
GO:0033523	histone H2B ubiquitination	1/665	12/18722	0.352165788990414	0.53871265390454	DTX3L	1
GO:0034086	maintenance of sister chromatid cohesion	1/665	12/18722	0.352165788990414	0.53871265390454	RB1	1
GO:0034088	maintenance of mitotic sister chromatid cohesion	1/665	12/18722	0.352165788990414	0.53871265390454	RB1	1
GO:0034154	toll-like receptor 7 signaling pathway	1/665	12/18722	0.352165788990414	0.53871265390454	RSAD2	1
GO:0034333	adherens junction assembly	1/665	12/18722	0.352165788990414	0.53871265390454	SMAD7	1
GO:0034370	triglyceride-rich lipoprotein particle remodeling	1/665	12/18722	0.352165788990414	0.53871265390454	APOE	1
GO:0034372	very-low-density lipoprotein particle remodeling	1/665	12/18722	0.352165788990414	0.53871265390454	APOE	1
GO:0035739	CD4-positive, alpha-beta T cell proliferation	1/665	12/18722	0.352165788990414	0.53871265390454	CD81	1
GO:0043248	proteasome assembly	1/665	12/18722	0.352165788990414	0.53871265390454	POMP	1
GO:0043383	negative T cell selection	1/665	12/18722	0.352165788990414	0.53871265390454	CD74	1
GO:0044650	adhesion of symbiont to host cell	1/665	12/18722	0.352165788990414	0.53871265390454	CD81	1
GO:0045117	azole transmembrane transport	1/665	12/18722	0.352165788990414	0.53871265390454	SLC25A19	1
GO:0045916	negative regulation of complement activation	1/665	12/18722	0.352165788990414	0.53871265390454	SERPING1	1
GO:0046385	deoxyribose phosphate biosynthetic process	1/665	12/18722	0.352165788990414	0.53871265390454	GUK1	1
GO:0046831	regulation of RNA export from nucleus	1/665	12/18722	0.352165788990414	0.53871265390454	SETD2	1
GO:0051095	regulation of helicase activity	1/665	12/18722	0.352165788990414	0.53871265390454	IFIT1	1
GO:0060019	radial glial cell differentiation	1/665	12/18722	0.352165788990414	0.53871265390454	RHOA	1
GO:0060134	prepulse inhibition	1/665	12/18722	0.352165788990414	0.53871265390454	PTEN	1
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	1/665	12/18722	0.352165788990414	0.53871265390454	SMAD7	1
GO:0060453	regulation of gastric acid secretion	1/665	12/18722	0.352165788990414	0.53871265390454	SGK1	1
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	1/665	12/18722	0.352165788990414	0.53871265390454	HAMP	1
GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	1/665	12/18722	0.352165788990414	0.53871265390454	RGS2	1
GO:0061307	cardiac neural crest cell differentiation involved in heart development	1/665	12/18722	0.352165788990414	0.53871265390454	CITED2	1
GO:0061308	cardiac neural crest cell development involved in heart development	1/665	12/18722	0.352165788990414	0.53871265390454	CITED2	1
GO:0061430	bone trabecula morphogenesis	1/665	12/18722	0.352165788990414	0.53871265390454	FBN2	1
GO:0061517	macrophage proliferation	1/665	12/18722	0.352165788990414	0.53871265390454	TREM2	1
GO:0070493	thrombin-activated receptor signaling pathway	1/665	12/18722	0.352165788990414	0.53871265390454	IQGAP2	1
GO:0071257	cellular response to electrical stimulus	1/665	12/18722	0.352165788990414	0.53871265390454	PTEN	1
GO:0071287	cellular response to manganese ion	1/665	12/18722	0.352165788990414	0.53871265390454	LRRK2	1
GO:0071712	ER-associated misfolded protein catabolic process	1/665	12/18722	0.352165788990414	0.53871265390454	RNF5	1
GO:0072182	regulation of nephron tubule epithelial cell differentiation	1/665	12/18722	0.352165788990414	0.53871265390454	STAT1	1
GO:0072683	T cell extravasation	1/665	12/18722	0.352165788990414	0.53871265390454	IL27RA	1
GO:0090085	regulation of protein deubiquitination	1/665	12/18722	0.352165788990414	0.53871265390454	TANK	1
GO:0090331	negative regulation of platelet aggregation	1/665	12/18722	0.352165788990414	0.53871265390454	CD9	1
GO:0090385	phagosome-lysosome fusion	1/665	12/18722	0.352165788990414	0.53871265390454	RAB20	1
GO:0090557	establishment of endothelial intestinal barrier	1/665	12/18722	0.352165788990414	0.53871265390454	MYD88	1
GO:0090677	reversible differentiation	1/665	12/18722	0.352165788990414	0.53871265390454	SOD2	1
GO:1901503	ether biosynthetic process	1/665	12/18722	0.352165788990414	0.53871265390454	ALOX5	1
GO:1901894	regulation of ATPase-coupled calcium transmembrane transporter activity	1/665	12/18722	0.352165788990414	0.53871265390454	C4orf3	1
GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	1/665	12/18722	0.352165788990414	0.53871265390454	NRP1	1
GO:1903332	regulation of protein folding	1/665	12/18722	0.352165788990414	0.53871265390454	GRN	1
GO:1903405	protein localization to nuclear body	1/665	12/18722	0.352165788990414	0.53871265390454	LARP7	1
GO:1903599	positive regulation of autophagy of mitochondrion	1/665	12/18722	0.352165788990414	0.53871265390454	BNIP3	1
GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA	1/665	12/18722	0.352165788990414	0.53871265390454	EGFR	1
GO:1904867	protein localization to Cajal body	1/665	12/18722	0.352165788990414	0.53871265390454	LARP7	1
GO:1905245	regulation of aspartic-type peptidase activity	1/665	12/18722	0.352165788990414	0.53871265390454	GRN	1
GO:2000035	regulation of stem cell division	1/665	12/18722	0.352165788990414	0.53871265390454	EVI2B	1
GO:2000508	regulation of dendritic cell chemotaxis	1/665	12/18722	0.352165788990414	0.53871265390454	SPI1	1
GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation	1/665	12/18722	0.352165788990414	0.53871265390454	CD81	1
GO:2001204	regulation of osteoclast development	1/665	12/18722	0.352165788990414	0.53871265390454	TYROBP	1
GO:0009408	response to heat	5/665	110/18722	0.352605218058087	0.53871265390454	HMOX1/IER5/SLU7/CDKN1A/CXCL12	5
GO:0018958	phenol-containing compound metabolic process	5/665	110/18722	0.352605218058087	0.53871265390454	NR4A2/LY6E/CGA/ITGAM/SLC16A10	5
GO:0043401	steroid hormone mediated signaling pathway	6/665	136/18722	0.353663911254175	0.53871265390454	YWHAH/DAB2/RHOA/PTGES3/PHB/PER1	6
GO:0001569	branching involved in blood vessel morphogenesis	2/665	35/18722	0.354553137006388	0.53871265390454	VEGFA/NRP1	2
GO:0001893	maternal placenta development	2/665	35/18722	0.354553137006388	0.53871265390454	JUNB/CITED2	2
GO:0002209	behavioral defense response	2/665	35/18722	0.354553137006388	0.53871265390454	APOE/EIF4E	2
GO:0003298	physiological muscle hypertrophy	2/665	35/18722	0.354553137006388	0.53871265390454	HAMP/RGS2	2
GO:0003301	physiological cardiac muscle hypertrophy	2/665	35/18722	0.354553137006388	0.53871265390454	HAMP/RGS2	2
GO:0008608	attachment of spindle microtubules to kinetochore	2/665	35/18722	0.354553137006388	0.53871265390454	RB1/RMDN1	2
GO:0010837	regulation of keratinocyte proliferation	2/665	35/18722	0.354553137006388	0.53871265390454	ZFP36/KLF9	2
GO:0015695	organic cation transport	2/665	35/18722	0.354553137006388	0.53871265390454	SLC38A2/SLC25A19	2
GO:0032205	negative regulation of telomere maintenance	2/665	35/18722	0.354553137006388	0.53871265390454	TERF2IP/HNRNPA1	2
GO:0032350	regulation of hormone metabolic process	2/665	35/18722	0.354553137006388	0.53871265390454	ADM/EGR1	2
GO:0039694	viral RNA genome replication	2/665	35/18722	0.354553137006388	0.53871265390454	CXCL8/PHB	2
GO:0045907	positive regulation of vasoconstriction	2/665	35/18722	0.354553137006388	0.53871265390454	RHOA/EGFR	2
GO:0045922	negative regulation of fatty acid metabolic process	2/665	35/18722	0.354553137006388	0.53871265390454	APOC1/INSIG2	2
GO:0046627	negative regulation of insulin receptor signaling pathway	2/665	35/18722	0.354553137006388	0.53871265390454	PIP4K2A/SOCS3	2
GO:0048821	erythrocyte development	2/665	35/18722	0.354553137006388	0.53871265390454	CITED2/KLF2	2
GO:0061049	cell growth involved in cardiac muscle cell development	2/665	35/18722	0.354553137006388	0.53871265390454	HAMP/RGS2	2
GO:0070536	protein K63-linked deubiquitination	2/665	35/18722	0.354553137006388	0.53871265390454	OTUD1/TNFAIP3	2
GO:0072528	pyrimidine-containing compound biosynthetic process	2/665	35/18722	0.354553137006388	0.53871265390454	UPP1/CMPK1	2
GO:0106056	regulation of calcineurin-mediated signaling	2/665	35/18722	0.354553137006388	0.53871265390454	CLEC7A/PRNP	2
GO:1905508	protein localization to microtubule organizing center	2/665	35/18722	0.354553137006388	0.53871265390454	SNX10/MAPRE1	2
GO:0046879	hormone secretion	12/665	295/18722	0.357047277585214	0.54176847554623	HLA-DRB1/ALOX5/GLUL/ADM/DYNLL1/IRS2/CGA/RAC1/ANXA1/EGFR/KIF5B/SLC16A10	12
GO:0001656	metanephros development	4/665	85/18722	0.357109361345966	0.54176847554623	CTSH/STAT1/EGR1/APH1A	4
GO:0009142	nucleoside triphosphate biosynthetic process	4/665	85/18722	0.357109361345966	0.54176847554623	TREM2/ALDOA/CMPK1/ENO1	4
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	4/665	85/18722	0.357109361345966	0.54176847554623	SOCS3/PARP9/HCLS1/ARL2BP	4
GO:0060021	roof of mouth development	4/665	85/18722	0.357109361345966	0.54176847554623	DHRS3/INSIG2/EPHB2/TIPARP	4
GO:0033866	nucleoside bisphosphate biosynthetic process	3/665	60/18722	0.359441141621001	0.54447499965144	ACSL1/PAPSS1/PAPSS2	3
GO:0034030	ribonucleoside bisphosphate biosynthetic process	3/665	60/18722	0.359441141621001	0.54447499965144	ACSL1/PAPSS1/PAPSS2	3
GO:0034033	purine nucleoside bisphosphate biosynthetic process	3/665	60/18722	0.359441141621001	0.54447499965144	ACSL1/PAPSS1/PAPSS2	3
GO:0051965	positive regulation of synapse assembly	3/665	60/18722	0.359441141621001	0.54447499965144	IL1RAP/EPHB2/AGRN	3
GO:0060038	cardiac muscle cell proliferation	3/665	60/18722	0.359441141621001	0.54447499965144	CITED2/PTEN/JARID2	3
GO:0006805	xenobiotic metabolic process	5/665	111/18722	0.359686356243275	0.54451452650901	ACSL1/AHR/VKORC1/GUK1/CYP1B1	5
GO:0015718	monocarboxylic acid transport	5/665	111/18722	0.359686356243275	0.54451452650901	SLC6A8/SLC16A3/CD36/ANXA1/ABCC3	5
GO:0030879	mammary gland development	6/665	137/18722	0.360016975160636	0.544849076293655	OAS2/VEGFA/HK2/CEBPB/IRS2/GPX1	6
GO:0043543	protein acylation	10/665	243/18722	0.362888086247365	0.549008588216223	NUPR1/GLUL/TERF2IP/BLOC1S1/ZDHHC20/GOLGA7/SPI1/CAMK1/MORF4L1/PER1	10
GO:0009755	hormone-mediated signaling pathway	8/665	190/18722	0.3629863623498	0.549008588216223	YWHAH/DAB2/ACSL1/CSNK2B/RHOA/PTGES3/PHB/PER1	8
GO:0045921	positive regulation of exocytosis	4/665	86/18722	0.365229290200515	0.55206495507803	HLA-F/ITGAM/PTAFR/SDCBP	4
GO:0048864	stem cell development	4/665	86/18722	0.365229290200515	0.55206495507803	CITED2/FN1/SETD2/NRP1	4
GO:0000956	nuclear-transcribed mRNA catabolic process	5/665	112/18722	0.366771704614486	0.552995672884917	ZFP36L2/SSB/ZFP36/TOB1/HELZ2	5
GO:0001676	long-chain fatty acid metabolic process	5/665	112/18722	0.366771704614486	0.552995672884917	ALOX5/ACSL1/PTGES3/CYP1B1/GPX1	5
GO:0043406	positive regulation of MAP kinase activity	5/665	112/18722	0.366771704614486	0.552995672884917	VEGFA/ADAM8/EGFR/LRRK2/PTK2B	5
GO:0010923	negative regulation of phosphatase activity	2/665	36/18722	0.367478705634037	0.552995672884917	PPP1R15A/LGALS3	2
GO:0043949	regulation of cAMP-mediated signaling	2/665	36/18722	0.367478705634037	0.552995672884917	UBE2B/RGS2	2
GO:0045191	regulation of isotype switching	2/665	36/18722	0.367478705634037	0.552995672884917	IL27RA/TFRC	2
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	2/665	36/18722	0.367478705634037	0.552995672884917	NCF1/PLAUR	2
GO:0045746	negative regulation of Notch signaling pathway	2/665	36/18722	0.367478705634037	0.552995672884917	NFKBIA/MMP14	2
GO:0046466	membrane lipid catabolic process	2/665	36/18722	0.367478705634037	0.552995672884917	HEXB/CYP1B1	2
GO:0051955	regulation of amino acid transport	2/665	36/18722	0.367478705634037	0.552995672884917	RGS2/KMO	2
GO:0060251	regulation of glial cell proliferation	2/665	36/18722	0.367478705634037	0.552995672884917	TSPO/EGFR	2
GO:0070306	lens fiber cell differentiation	2/665	36/18722	0.367478705634037	0.552995672884917	VIM/SKIL	2
GO:0086010	membrane depolarization during action potential	2/665	36/18722	0.367478705634037	0.552995672884917	YWHAH/SCN9A	2
GO:0006900	vesicle budding from membrane	3/665	61/18722	0.369193996554976	0.552995672884917	S100A10/ANXA2/CHMP5	3
GO:0050796	regulation of insulin secretion	7/665	165/18722	0.37079004366791	0.552995672884917	HLA-DRB1/ALOX5/GLUL/DYNLL1/IRS2/RAC1/KIF5B	7
GO:0006814	sodium ion transport	10/665	245/18722	0.372414876141553	0.552995672884917	YWHAH/SLC6A8/SGK1/FXYD5/GLRX/SLC38A2/WNK1/KIF5B/SCN9A/PER1	10
GO:0030216	keratinocyte differentiation	6/665	139/18722	0.372741876491475	0.552995672884917	TXNIP/ERRFI1/ST14/ZFP36/ANXA1/PLEC	6
GO:0045598	regulation of fat cell differentiation	6/665	139/18722	0.372741876491475	0.552995672884917	ZFP36L2/ALOX5/CEBPB/ZFP36/ZNF385A/CCDC85B	6
GO:0019646	aerobic electron transport chain	4/665	87/18722	0.373344294984497	0.552995672884917	SDHD/DNAJC15/CYCS/COX5B	4
GO:0051262	protein tetramerization	4/665	87/18722	0.373344294984497	0.552995672884917	HLA-DRB1/B2M/ALDOA/SOD2	4
GO:1901606	alpha-amino acid catabolic process	4/665	87/18722	0.373344294984497	0.552995672884917	IL4I1/GLUL/DDAH2/KMO	4
GO:2000177	regulation of neural precursor cell proliferation	4/665	87/18722	0.373344294984497	0.552995672884917	VEGFA/FLNA/RHOA/LRRK2	4
GO:0008380	RNA splicing	17/665	434/18722	0.374467822498129	0.552995672884917	SNRPB/SLC38A2/LGALS3/YBX1/AHNAK/CWC15/SLU7/NCL/LARP7/ZCRB1/SF3B6/HNRNPA1/CIR1/IVNS1ABP/HNRNPH2/LSM6/ZC3H13	17
GO:0006066	alcohol metabolic process	14/665	353/18722	0.374893478156704	0.552995672884917	APOE/TPI1/IDH1/ALDH2/PTEN/DHRS3/PTAFR/OSBPL1A/SOAT1/INSIG2/PTK2B/CYP1B1/ALDH3A2/GALK1	14
GO:0001833	inner cell mass cell proliferation	1/665	13/18722	0.375191430375843	0.552995672884917	COPS2	1
GO:0001973	G protein-coupled adenosine receptor signaling pathway	1/665	13/18722	0.375191430375843	0.552995672884917	ADORA3	1
GO:0002638	negative regulation of immunoglobulin production	1/665	13/18722	0.375191430375843	0.552995672884917	FCGR2B	1
GO:0003334	keratinocyte development	1/665	13/18722	0.375191430375843	0.552995672884917	PLEC	1
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	1/665	13/18722	0.375191430375843	0.552995672884917	STAT1	1
GO:0006264	mitochondrial DNA replication	1/665	13/18722	0.375191430375843	0.552995672884917	RRM2B	1
GO:0007494	midgut development	1/665	13/18722	0.375191430375843	0.552995672884917	EGFR	1
GO:0007567	parturition	1/665	13/18722	0.375191430375843	0.552995672884917	PTAFR	1
GO:0009650	UV protection	1/665	13/18722	0.375191430375843	0.552995672884917	GPX1	1
GO:0010745	negative regulation of macrophage derived foam cell differentiation	1/665	13/18722	0.375191430375843	0.552995672884917	NFKBIA	1
GO:0010755	regulation of plasminogen activation	1/665	13/18722	0.375191430375843	0.552995672884917	ENO1	1
GO:0010958	regulation of amino acid import across plasma membrane	1/665	13/18722	0.375191430375843	0.552995672884917	RGS2	1
GO:0010960	magnesium ion homeostasis	1/665	13/18722	0.375191430375843	0.552995672884917	EGFR	1
GO:0015801	aromatic amino acid transport	1/665	13/18722	0.375191430375843	0.552995672884917	SLC16A10	1
GO:0015809	arginine transport	1/665	13/18722	0.375191430375843	0.552995672884917	SLC11A1	1
GO:0015816	glycine transport	1/665	13/18722	0.375191430375843	0.552995672884917	RGS2	1
GO:0016024	CDP-diacylglycerol biosynthetic process	1/665	13/18722	0.375191430375843	0.552995672884917	AGPAT2	1
GO:0016078	tRNA catabolic process	1/665	13/18722	0.375191430375843	0.552995672884917	ANG	1
GO:0016322	neuron remodeling	1/665	13/18722	0.375191430375843	0.552995672884917	C1QA	1
GO:0021554	optic nerve development	1/665	13/18722	0.375191430375843	0.552995672884917	EPHB2	1
GO:0030497	fatty acid elongation	1/665	13/18722	0.375191430375843	0.552995672884917	HACD4	1
GO:0032230	positive regulation of synaptic transmission, GABAergic	1/665	13/18722	0.375191430375843	0.552995672884917	KIF5B	1
GO:0032905	transforming growth factor beta1 production	1/665	13/18722	0.375191430375843	0.552995672884917	TYROBP	1
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	1/665	13/18722	0.375191430375843	0.552995672884917	EAPP	1
GO:0033689	negative regulation of osteoblast proliferation	1/665	13/18722	0.375191430375843	0.552995672884917	EIF2AK2	1
GO:0034982	mitochondrial protein processing	1/665	13/18722	0.375191430375843	0.552995672884917	LRRK2	1
GO:0035588	G protein-coupled purinergic receptor signaling pathway	1/665	13/18722	0.375191430375843	0.552995672884917	ADORA3	1
GO:0042761	very long-chain fatty acid biosynthetic process	1/665	13/18722	0.375191430375843	0.552995672884917	HACD4	1
GO:0043201	response to leucine	1/665	13/18722	0.375191430375843	0.552995672884917	RRAGD	1
GO:0043247	telomere maintenance in response to DNA damage	1/665	13/18722	0.375191430375843	0.552995672884917	TERF2IP	1
GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	1/665	13/18722	0.375191430375843	0.552995672884917	NCF1	1
GO:0046642	negative regulation of alpha-beta T cell proliferation	1/665	13/18722	0.375191430375843	0.552995672884917	TNFRSF14	1
GO:0048302	regulation of isotype switching to IgG isotypes	1/665	13/18722	0.375191430375843	0.552995672884917	IL27RA	1
GO:0051451	myoblast migration	1/665	13/18722	0.375191430375843	0.552995672884917	ANXA1	1
GO:0051709	regulation of killing of cells of other organism	1/665	13/18722	0.375191430375843	0.552995672884917	CLEC7A	1
GO:0051956	negative regulation of amino acid transport	1/665	13/18722	0.375191430375843	0.552995672884917	RGS2	1
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	1/665	13/18722	0.375191430375843	0.552995672884917	IRF7	1
GO:0060707	trophoblast giant cell differentiation	1/665	13/18722	0.375191430375843	0.552995672884917	SOCS3	1
GO:0061000	negative regulation of dendritic spine development	1/665	13/18722	0.375191430375843	0.552995672884917	PTEN	1
GO:0070234	positive regulation of T cell apoptotic process	1/665	13/18722	0.375191430375843	0.552995672884917	ADAM8	1
GO:0070254	mucus secretion	1/665	13/18722	0.375191430375843	0.552995672884917	EGFR	1
GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway	1/665	13/18722	0.375191430375843	0.552995672884917	TNFAIP3	1
GO:0070914	UV-damage excision repair	1/665	13/18722	0.375191430375843	0.552995672884917	XPC	1
GO:0071696	ectodermal placode development	1/665	13/18722	0.375191430375843	0.552995672884917	NRP1	1
GO:0072578	neurotransmitter-gated ion channel clustering	1/665	13/18722	0.375191430375843	0.552995672884917	APOE	1
GO:0090042	tubulin deacetylation	1/665	13/18722	0.375191430375843	0.552995672884917	FLNA	1
GO:0098840	protein transport along microtubule	1/665	13/18722	0.375191430375843	0.552995672884917	KIF5B	1
GO:0099118	microtubule-based protein transport	1/665	13/18722	0.375191430375843	0.552995672884917	KIF5B	1
GO:0106070	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	1/665	13/18722	0.375191430375843	0.552995672884917	ARRDC3	1
GO:0110096	cellular response to aldehyde	1/665	13/18722	0.375191430375843	0.552995672884917	ESD	1
GO:1900115	extracellular regulation of signal transduction	1/665	13/18722	0.375191430375843	0.552995672884917	FBN2	1
GO:1900116	extracellular negative regulation of signal transduction	1/665	13/18722	0.375191430375843	0.552995672884917	FBN2	1
GO:1900121	negative regulation of receptor binding	1/665	13/18722	0.375191430375843	0.552995672884917	B2M	1
GO:1902260	negative regulation of delayed rectifier potassium channel activity	1/665	13/18722	0.375191430375843	0.552995672884917	KCNE1	1
GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	1/665	13/18722	0.375191430375843	0.552995672884917	NRP1	1
GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	1/665	13/18722	0.375191430375843	0.552995672884917	LAMTOR5	1
GO:1903789	regulation of amino acid transmembrane transport	1/665	13/18722	0.375191430375843	0.552995672884917	RGS2	1
GO:1903977	positive regulation of glial cell migration	1/665	13/18722	0.375191430375843	0.552995672884917	TREM2	1
GO:1904925	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	1/665	13/18722	0.375191430375843	0.552995672884917	HK2	1
GO:1905244	regulation of modification of synaptic structure	1/665	13/18722	0.375191430375843	0.552995672884917	RHOA	1
GO:0046942	carboxylic acid transport	11/665	273/18722	0.378074634734015	0.55591183575754	SLC11A1/SLC6A8/SLC16A3/SLC1A3/CD36/SLC38A2/ANXA1/RGS2/ABCC3/KMO/PSAP	11
GO:0009311	oligosaccharide metabolic process	3/665	62/18722	0.378919745436993	0.55591183575754	FBP1/ST8SIA4/HEXB	3
GO:0010573	vascular endothelial growth factor production	3/665	62/18722	0.378919745436993	0.55591183575754	SULF2/C5AR1/CYP1B1	3
GO:0046824	positive regulation of nucleocytoplasmic transport	3/665	62/18722	0.378919745436993	0.55591183575754	FLNA/HCLS1/CAMK1	3
GO:0046847	filopodium assembly	3/665	62/18722	0.378919745436993	0.55591183575754	RALA/AGRN/NRP1	3
GO:0060135	maternal process involved in female pregnancy	3/665	62/18722	0.378919745436993	0.55591183575754	JUNB/CITED2/RGS2	3
GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	3/665	62/18722	0.378919745436993	0.55591183575754	RAB8A/RAP1A/STX3	3
GO:1902750	negative regulation of cell cycle G2/M phase transition	3/665	62/18722	0.378919745436993	0.55591183575754	ATF5/CDKN1A/FOXN3	3
GO:0006623	protein targeting to vacuole	2/665	37/18722	0.380301859471959	0.55591183575754	SCARB2/VPS13A	2
GO:0006904	vesicle docking involved in exocytosis	2/665	37/18722	0.380301859471959	0.55591183575754	RAB8A/RAB13	2
GO:0014904	myotube cell development	2/665	37/18722	0.380301859471959	0.55591183575754	PLEC/GPX1	2
GO:0016202	regulation of striated muscle tissue development	2/665	37/18722	0.380301859471959	0.55591183575754	YBX3/IGF2	2
GO:0030513	positive regulation of BMP signaling pathway	2/665	37/18722	0.380301859471959	0.55591183575754	ACVRL1/FBXL15	2
GO:0031112	positive regulation of microtubule polymerization or depolymerization	2/665	37/18722	0.380301859471959	0.55591183575754	MAPRE1/RAC1	2
GO:0033120	positive regulation of RNA splicing	2/665	37/18722	0.380301859471959	0.55591183575754	SLC38A2/NCL	2
GO:0042401	cellular biogenic amine biosynthetic process	2/665	37/18722	0.380301859471959	0.55591183575754	NR4A2/OAZ1	2
GO:0045616	regulation of keratinocyte differentiation	2/665	37/18722	0.380301859471959	0.55591183575754	ERRFI1/ZFP36	2
GO:0046473	phosphatidic acid metabolic process	2/665	37/18722	0.380301859471959	0.55591183575754	AGPAT2/ABHD5	2
GO:0051567	histone H3-K9 methylation	2/665	37/18722	0.380301859471959	0.55591183575754	LMNA/JARID2	2
GO:0051954	positive regulation of amine transport	2/665	37/18722	0.380301859471959	0.55591183575754	KMO/CXCL12	2
GO:0060306	regulation of membrane repolarization	2/665	37/18722	0.380301859471959	0.55591183575754	FLNA/KCNE1	2
GO:0060428	lung epithelium development	2/665	37/18722	0.380301859471959	0.55591183575754	ERRFI1/KLF2	2
GO:0071542	dopaminergic neuron differentiation	2/665	37/18722	0.380301859471959	0.55591183575754	VEGFA/NR4A2	2
GO:0071985	multivesicular body sorting pathway	2/665	37/18722	0.380301859471959	0.55591183575754	VTA1/CHMP5	2
GO:0072529	pyrimidine-containing compound catabolic process	2/665	37/18722	0.380301859471959	0.55591183575754	TYMP/UPP1	2
GO:0090218	positive regulation of lipid kinase activity	2/665	37/18722	0.380301859471959	0.55591183575754	PTK2B/CD81	2
GO:1900016	negative regulation of cytokine production involved in inflammatory response	2/665	37/18722	0.380301859471959	0.55591183575754	TREM2/PYCARD	2
GO:1900077	negative regulation of cellular response to insulin stimulus	2/665	37/18722	0.380301859471959	0.55591183575754	PIP4K2A/SOCS3	2
GO:0048705	skeletal system morphogenesis	9/665	220/18722	0.380880445492247	0.556198429938975	ACP5/CITED2/DHRS3/FBN2/INSIG2/MMP14/FOXN3/TIPARP/SETD2	9
GO:0019751	polyol metabolic process	5/665	114/18722	0.380945564489391	0.556198429938975	TPI1/PTEN/PTAFR/PTK2B/GALK1	5
GO:0021987	cerebral cortex development	5/665	114/18722	0.380945564489391	0.556198429938975	SLC38A2/BNIP3/FLNA/RHOA/BCL2A1	5
GO:1904892	regulation of receptor signaling pathway via STAT	5/665	114/18722	0.380945564489391	0.556198429938975	CD300A/SOCS3/IL7R/PTK2B/CYP1B1	5
GO:0007260	tyrosine phosphorylation of STAT protein	4/665	88/18722	0.381450994711645	0.556609349300315	SOCS3/PARP9/HCLS1/ARL2BP	4
GO:1901657	glycosyl compound metabolic process	4/665	88/18722	0.381450994711645	0.556609349300315	NT5C3A/TYMP/UPP1/ERH	4
GO:0032355	response to estradiol	6/665	141/18722	0.385480234992062	0.562323677109054	DUSP1/TXNIP/PTEN/ANXA1/GPI/EGFR	6
GO:0099601	regulation of neurotransmitter receptor activity	3/665	63/18722	0.388613144650526	0.564307815542063	IFNGR2/PTK2B/EPHB2	3
GO:0030073	insulin secretion	8/665	195/18722	0.390007748965553	0.564307815542063	HLA-DRB1/ALOX5/GLUL/DYNLL1/IRS2/RAC1/ANXA1/KIF5B	8
GO:0015931	nucleobase-containing compound transport	9/665	222/18722	0.391020777414079	0.564307815542063	MX2/SSB/ZFP36/NUP58/SLC25A19/YBX1/HNRNPA1/MRPL18/SETD2	9
GO:0006882	cellular zinc ion homeostasis	2/665	38/18722	0.393013568958595	0.564307815542063	MT1X/S100A8	2
GO:0009309	amine biosynthetic process	2/665	38/18722	0.393013568958595	0.564307815542063	NR4A2/OAZ1	2
GO:0010719	negative regulation of epithelial to mesenchymal transition	2/665	38/18722	0.393013568958595	0.564307815542063	PTEN/SMAD7	2
GO:0032717	negative regulation of interleukin-8 production	2/665	38/18722	0.393013568958595	0.564307815542063	KLF4/ANXA1	2
GO:0032941	secretion by tissue	2/665	38/18722	0.393013568958595	0.564307815542063	EGFR/WNK1	2
GO:0035337	fatty-acyl-CoA metabolic process	2/665	38/18722	0.393013568958595	0.564307815542063	ACSL1/HSD17B4	2
GO:0042596	fear response	2/665	38/18722	0.393013568958595	0.564307815542063	APOE/EIF4E	2
GO:0046329	negative regulation of JNK cascade	2/665	38/18722	0.393013568958595	0.564307815542063	AIDA/PER1	2
GO:0048713	regulation of oligodendrocyte differentiation	2/665	38/18722	0.393013568958595	0.564307815542063	CXCR4/TLR2	2
GO:0099622	cardiac muscle cell membrane repolarization	2/665	38/18722	0.393013568958595	0.564307815542063	FLNA/KCNE1	2
GO:1901186	positive regulation of ERBB signaling pathway	2/665	38/18722	0.393013568958595	0.564307815542063	NCF1/PLAUR	2
GO:0000075	cell cycle checkpoint signaling	7/665	169/18722	0.394117387369254	0.564307815542063	DUSP1/RPS27L/RPA2/PLK3/CDKN1A/FOXN3/XPC	7
GO:0009152	purine ribonucleotide biosynthetic process	7/665	169/18722	0.394117387369254	0.564307815542063	TREM2/ALDOA/ACSL1/PAPSS1/ENO1/PAPSS2/GUK1	7
GO:0006720	isoprenoid metabolic process	5/665	116/18722	0.395108277633272	0.564307815542063	DHRS3/EGFR/RBP1/CYP1B1/ALDH3A2	5
GO:0008286	insulin receptor signaling pathway	5/665	116/18722	0.395108277633272	0.564307815542063	IRS2/PIP4K2A/GRB2/SOCS3/IGF2	5
GO:0035967	cellular response to topologically incorrect protein	5/665	116/18722	0.395108277633272	0.564307815542063	EIF2AK2/ERO1A/ATF3/PPP1R15A/RNF5	5
GO:0043200	response to amino acid	5/665	116/18722	0.395108277633272	0.564307815542063	CAPN2/CEBPB/RHOA/LAMTOR5/RRAGD	5
GO:0031032	actomyosin structure organization	8/665	196/18722	0.395423583965029	0.564307815542063	S100A10/RAC1/RHOA/PLEC/RHOC/EPB41/PTK2B/NRP1	8
GO:0090276	regulation of peptide hormone secretion	8/665	196/18722	0.395423583965029	0.564307815542063	HLA-DRB1/ALOX5/GLUL/DYNLL1/IRS2/RAC1/EGFR/KIF5B	8
GO:0001921	positive regulation of receptor recycling	1/665	14/18722	0.397399870100044	0.564307815542063	ANXA2	1
GO:0002517	T cell tolerance induction	1/665	14/18722	0.397399870100044	0.564307815542063	HLA-B	1
GO:0002756	MyD88-independent toll-like receptor signaling pathway	1/665	14/18722	0.397399870100044	0.564307815542063	IRF7	1
GO:0006596	polyamine biosynthetic process	1/665	14/18722	0.397399870100044	0.564307815542063	OAZ1	1
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	1/665	14/18722	0.397399870100044	0.564307815542063	ERRFI1	1
GO:0007638	mechanosensory behavior	1/665	14/18722	0.397399870100044	0.564307815542063	SLC1A3	1
GO:0009158	ribonucleoside monophosphate catabolic process	1/665	14/18722	0.397399870100044	0.564307815542063	UPP1	1
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1/665	14/18722	0.397399870100044	0.564307815542063	GBP1	1
GO:0010839	negative regulation of keratinocyte proliferation	1/665	14/18722	0.397399870100044	0.564307815542063	KLF9	1
GO:0010896	regulation of triglyceride catabolic process	1/665	14/18722	0.397399870100044	0.564307815542063	ABHD5	1
GO:0018158	protein oxidation	1/665	14/18722	0.397399870100044	0.564307815542063	GPX1	1
GO:0022038	corpus callosum development	1/665	14/18722	0.397399870100044	0.564307815542063	EPHB2	1
GO:0030007	cellular potassium ion homeostasis	1/665	14/18722	0.397399870100044	0.564307815542063	KCNMA1	1
GO:0030049	muscle filament sliding	1/665	14/18722	0.397399870100044	0.564307815542063	MYL6	1
GO:0031115	negative regulation of microtubule polymerization	1/665	14/18722	0.397399870100044	0.564307815542063	MAPRE1	1
GO:0031650	regulation of heat generation	1/665	14/18722	0.397399870100044	0.564307815542063	ARRDC3	1
GO:0033605	positive regulation of catecholamine secretion	1/665	14/18722	0.397399870100044	0.564307815542063	CXCL12	1
GO:0034111	negative regulation of homotypic cell-cell adhesion	1/665	14/18722	0.397399870100044	0.564307815542063	CD9	1
GO:0035437	maintenance of protein localization in endoplasmic reticulum	1/665	14/18722	0.397399870100044	0.564307815542063	INSIG2	1
GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	1/665	14/18722	0.397399870100044	0.564307815542063	PTAFR	1
GO:0035630	bone mineralization involved in bone maturation	1/665	14/18722	0.397399870100044	0.564307815542063	SNX10	1
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	1/665	14/18722	0.397399870100044	0.564307815542063	PTPN12	1
GO:0036295	cellular response to increased oxygen levels	1/665	14/18722	0.397399870100044	0.564307815542063	ATP6V1G1	1
GO:0042415	norepinephrine metabolic process	1/665	14/18722	0.397399870100044	0.564307815542063	LY6E	1
GO:0043144	sno(s)RNA processing	1/665	14/18722	0.397399870100044	0.564307815542063	LARP7	1
GO:0043173	nucleotide salvage	1/665	14/18722	0.397399870100044	0.564307815542063	UPP1	1
GO:0043249	erythrocyte maturation	1/665	14/18722	0.397399870100044	0.564307815542063	KLF2	1
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	1/665	14/18722	0.397399870100044	0.564307815542063	ZNF385A	1
GO:0043650	dicarboxylic acid biosynthetic process	1/665	14/18722	0.397399870100044	0.564307815542063	KMO	1
GO:0043922	negative regulation by host of viral transcription	1/665	14/18722	0.397399870100044	0.564307815542063	JUN	1
GO:0045059	positive thymic T cell selection	1/665	14/18722	0.397399870100044	0.564307815542063	CD74	1
GO:0045472	response to ether	1/665	14/18722	0.397399870100044	0.564307815542063	PTAFR	1
GO:0045579	positive regulation of B cell differentiation	1/665	14/18722	0.397399870100044	0.564307815542063	MMP14	1
GO:0045989	positive regulation of striated muscle contraction	1/665	14/18722	0.397399870100044	0.564307815542063	RGS2	1
GO:0046131	pyrimidine ribonucleoside metabolic process	1/665	14/18722	0.397399870100044	0.564307815542063	UPP1	1
GO:0046133	pyrimidine ribonucleoside catabolic process	1/665	14/18722	0.397399870100044	0.564307815542063	UPP1	1
GO:0046325	negative regulation of glucose import	1/665	14/18722	0.397399870100044	0.564307815542063	PEA15	1
GO:0046341	CDP-diacylglycerol metabolic process	1/665	14/18722	0.397399870100044	0.564307815542063	AGPAT2	1
GO:0046479	glycosphingolipid catabolic process	1/665	14/18722	0.397399870100044	0.564307815542063	HEXB	1
GO:0047484	regulation of response to osmotic stress	1/665	14/18722	0.397399870100044	0.564307815542063	YBX3	1
GO:0048291	isotype switching to IgG isotypes	1/665	14/18722	0.397399870100044	0.564307815542063	IL27RA	1
GO:0048368	lateral mesoderm development	1/665	14/18722	0.397399870100044	0.564307815542063	CITED2	1
GO:0048681	negative regulation of axon regeneration	1/665	14/18722	0.397399870100044	0.564307815542063	PTEN	1
GO:0051547	regulation of keratinocyte migration	1/665	14/18722	0.397399870100044	0.564307815542063	PTEN	1
GO:0051589	negative regulation of neurotransmitter transport	1/665	14/18722	0.397399870100044	0.564307815542063	RAP1A	1
GO:0060354	negative regulation of cell adhesion molecule production	1/665	14/18722	0.397399870100044	0.564307815542063	CXCL8	1
GO:0060576	intestinal epithelial cell development	1/665	14/18722	0.397399870100044	0.564307815542063	CDKN1A	1
GO:0060732	positive regulation of inositol phosphate biosynthetic process	1/665	14/18722	0.397399870100044	0.564307815542063	PTAFR	1
GO:0070307	lens fiber cell development	1/665	14/18722	0.397399870100044	0.564307815542063	VIM	1
GO:0070986	left/right axis specification	1/665	14/18722	0.397399870100044	0.564307815542063	CITED2	1
GO:0071236	cellular response to antibiotic	1/665	14/18722	0.397399870100044	0.564307815542063	CRIP1	1
GO:0071481	cellular response to X-ray	1/665	14/18722	0.397399870100044	0.564307815542063	HAMP	1
GO:0072160	nephron tubule epithelial cell differentiation	1/665	14/18722	0.397399870100044	0.564307815542063	STAT1	1
GO:0072350	tricarboxylic acid metabolic process	1/665	14/18722	0.397399870100044	0.564307815542063	IDH1	1
GO:0072531	pyrimidine-containing compound transmembrane transport	1/665	14/18722	0.397399870100044	0.564307815542063	SLC25A19	1
GO:0086103	G protein-coupled receptor signaling pathway involved in heart process	1/665	14/18722	0.397399870100044	0.564307815542063	RGS2	1
GO:0090239	regulation of histone H4 acetylation	1/665	14/18722	0.397399870100044	0.564307815542063	SPI1	1
GO:0097091	synaptic vesicle clustering	1/665	14/18722	0.397399870100044	0.564307815542063	PTEN	1
GO:0099638	endosome to plasma membrane protein transport	1/665	14/18722	0.397399870100044	0.564307815542063	RAB8A	1
GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	1/665	14/18722	0.397399870100044	0.564307815542063	GBP1	1
GO:1900037	regulation of cellular response to hypoxia	1/665	14/18722	0.397399870100044	0.564307815542063	ENO1	1
GO:1901722	regulation of cell proliferation involved in kidney development	1/665	14/18722	0.397399870100044	0.564307815542063	EGR1	1
GO:1901857	positive regulation of cellular respiration	1/665	14/18722	0.397399870100044	0.564307815542063	NUPR1	1
GO:1902036	regulation of hematopoietic stem cell differentiation	1/665	14/18722	0.397399870100044	0.564307815542063	EIF2AK2	1
GO:1904923	regulation of autophagy of mitochondrion in response to mitochondrial depolarization	1/665	14/18722	0.397399870100044	0.564307815542063	HK2	1
GO:1905049	negative regulation of metallopeptidase activity	1/665	14/18722	0.397399870100044	0.564307815542063	TIMP1	1
GO:1905065	positive regulation of vascular associated smooth muscle cell differentiation	1/665	14/18722	0.397399870100044	0.564307815542063	SOD2	1
GO:1905208	negative regulation of cardiocyte differentiation	1/665	14/18722	0.397399870100044	0.564307815542063	EGFR	1
GO:1990173	protein localization to nucleoplasm	1/665	14/18722	0.397399870100044	0.564307815542063	LARP7	1
GO:2001140	positive regulation of phospholipid transport	1/665	14/18722	0.397399870100044	0.564307815542063	APOE	1
GO:2001256	regulation of store-operated calcium entry	1/665	14/18722	0.397399870100044	0.564307815542063	SARAF	1
GO:0006865	amino acid transport	6/665	143/18722	0.398218476343712	0.564735461768019	SLC11A1/SLC1A3/SLC38A2/RGS2/KMO/SLC16A10	6
GO:0046579	positive regulation of Ras protein signal transduction	3/665	64/18722	0.398269173741832	0.564735461768019	SHOC2/RAC1/PIK3CB	3
GO:0046854	phosphatidylinositol phosphate biosynthetic process	3/665	64/18722	0.398269173741832	0.564735461768019	PIP4K2A/SOCS3/PIK3CB	3
GO:0050771	negative regulation of axonogenesis	3/665	64/18722	0.398269173741832	0.564735461768019	PTEN/EPHB2/NRP1	3
GO:1900076	regulation of cellular response to insulin stimulus	3/665	64/18722	0.398269173741832	0.564735461768019	PIP4K2A/SOCS3/IGF2	3
GO:0009914	hormone transport	12/665	306/18722	0.404634421338798	0.573293501447067	HLA-DRB1/ALOX5/GLUL/ADM/DYNLL1/IRS2/CGA/RAC1/ANXA1/EGFR/KIF5B/SLC16A10	12
GO:0001941	postsynaptic membrane organization	2/665	39/18722	0.405605573149245	0.573293501447067	APOE/EPHB2	2
GO:0007618	mating	2/665	39/18722	0.405605573149245	0.573293501447067	PTEN/HEXB	2
GO:0042417	dopamine metabolic process	2/665	39/18722	0.405605573149245	0.573293501447067	NR4A2/ITGAM	2
GO:0045823	positive regulation of heart contraction	2/665	39/18722	0.405605573149245	0.573293501447067	ADM/RGS2	2
GO:0046326	positive regulation of glucose import	2/665	39/18722	0.405605573149245	0.573293501447067	IRS2/RAP1A	2
GO:0051154	negative regulation of striated muscle cell differentiation	2/665	39/18722	0.405605573149245	0.573293501447067	RGS2/YBX1	2
GO:0090207	regulation of triglyceride metabolic process	2/665	39/18722	0.405605573149245	0.573293501447067	APOE/ABHD5	2
GO:1901021	positive regulation of calcium ion transmembrane transporter activity	2/665	39/18722	0.405605573149245	0.573293501447067	CALM1/CALM3	2
GO:1901861	regulation of muscle tissue development	2/665	39/18722	0.405605573149245	0.573293501447067	YBX3/IGF2	2
GO:0006354	DNA-templated transcription, elongation	4/665	91/18722	0.405688781607512	0.573293501447067	LARP7/EAF1/EAPP/SETD2	4
GO:0006885	regulation of pH	4/665	91/18722	0.405688781607512	0.573293501447067	SLC11A1/RAB20/LRRK2/GRN	4
GO:0045017	glycerolipid biosynthetic process	10/665	252/18722	0.4059203100296	0.573457629575643	CAPN2/PLSCR1/ACSL1/ANG/PIP4K2A/PTEN/SOCS3/AGPAT2/PIK3CB/ABHD5	10
GO:0038034	signal transduction in absence of ligand	3/665	65/18722	0.407883032684753	0.575576000125845	IFI6/MCL1/BCL2A1	3
GO:0046503	glycerolipid catabolic process	3/665	65/18722	0.407883032684753	0.575576000125845	APOC1/GPCPD1/ABHD5	3
GO:0090307	mitotic spindle assembly	3/665	65/18722	0.407883032684753	0.575576000125845	FLNA/RHOA/CHMP5	3
GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	3/665	65/18722	0.407883032684753	0.575576000125845	IFI6/MCL1/BCL2A1	3
GO:0061351	neural precursor cell proliferation	6/665	145/18722	0.410943410062848	0.575805185160378	ATF5/VEGFA/C5AR1/FLNA/RHOA/LRRK2	6
GO:0031058	positive regulation of histone modification	4/665	92/18722	0.413730227699589	0.575805185160378	VEGFA/LMNA/LRRK2/JARID2	4
GO:0007409	axonogenesis	16/665	418/18722	0.415742752825717	0.575805185160378	ALCAM/VEGFA/APOE/S100A6/NR4A2/DPYSL2/RAB8A/SKIL/PTEN/RAC1/KIF5B/EPHB2/FN1/CXCL12/SIPA1L1/NRP1	16
GO:0099003	vesicle-mediated transport in synapse	8/665	200/18722	0.417090761846848	0.575805185160378	CALM1/RAB8A/RAP1A/FCHO2/PTEN/LRRK2/CALM3/STX3	8
GO:0032715	negative regulation of interleukin-6 production	3/665	66/18722	0.41745013882991	0.575805185160378	TNFAIP3/KLF2/IL27RA	3
GO:0045600	positive regulation of fat cell differentiation	3/665	66/18722	0.41745013882991	0.575805185160378	CEBPB/ZFP36/ZNF385A	3
GO:0046626	regulation of insulin receptor signaling pathway	3/665	66/18722	0.41745013882991	0.575805185160378	PIP4K2A/SOCS3/IGF2	3
GO:1902476	chloride transmembrane transport	3/665	66/18722	0.41745013882991	0.575805185160378	SLC1A3/CLIC2/GABRB2	3
GO:0014037	Schwann cell differentiation	2/665	40/18722	0.418070336648154	0.575805185160378	NDRG1/PLEC	2
GO:0032892	positive regulation of organic acid transport	2/665	40/18722	0.418070336648154	0.575805185160378	ACSL1/KMO	2
GO:0045777	positive regulation of blood pressure	2/665	40/18722	0.418070336648154	0.575805185160378	RHOA/WNK1	2
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	2/665	40/18722	0.418070336648154	0.575805185160378	CALM1/CALM3	2
GO:0055069	zinc ion homeostasis	2/665	40/18722	0.418070336648154	0.575805185160378	MT1X/S100A8	2
GO:0060412	ventricular septum morphogenesis	2/665	40/18722	0.418070336648154	0.575805185160378	CITED2/SMAD7	2
GO:0072210	metanephric nephron development	2/665	40/18722	0.418070336648154	0.575805185160378	STAT1/EGR1	2
GO:0097352	autophagosome maturation	2/665	40/18722	0.418070336648154	0.575805185160378	CALM1/MAP1LC3B	2
GO:1901998	toxin transport	2/665	40/18722	0.418070336648154	0.575805185160378	BNIP3/NRP1	2
GO:2000142	regulation of DNA-templated transcription, initiation	2/665	40/18722	0.418070336648154	0.575805185160378	JUN/PSMC6	2
GO:2000781	positive regulation of double-strand break repair	2/665	40/18722	0.418070336648154	0.575805185160378	DTX3L/PARP9	2
GO:0002070	epithelial cell maturation	1/665	15/18722	0.418820069286674	0.575805185160378	CDKN1A	1
GO:0002836	positive regulation of response to tumor cell	1/665	15/18722	0.418820069286674	0.575805185160378	HLA-DRB1	1
GO:0002839	positive regulation of immune response to tumor cell	1/665	15/18722	0.418820069286674	0.575805185160378	HLA-DRB1	1
GO:0006098	pentose-phosphate shunt	1/665	15/18722	0.418820069286674	0.575805185160378	PGAM1	1
GO:0006570	tyrosine metabolic process	1/665	15/18722	0.418820069286674	0.575805185160378	IL4I1	1
GO:0010273	detoxification of copper ion	1/665	15/18722	0.418820069286674	0.575805185160378	MT1X	1
GO:0010452	histone H3-K36 methylation	1/665	15/18722	0.418820069286674	0.575805185160378	SETD2	1
GO:0010752	regulation of cGMP-mediated signaling	1/665	15/18722	0.418820069286674	0.575805185160378	PTK2B	1
GO:0010820	positive regulation of T cell chemotaxis	1/665	15/18722	0.418820069286674	0.575805185160378	WNK1	1
GO:0014048	regulation of glutamate secretion	1/665	15/18722	0.418820069286674	0.575805185160378	KMO	1
GO:0015671	oxygen transport	1/665	15/18722	0.418820069286674	0.575805185160378	HBG1	1
GO:0016114	terpenoid biosynthetic process	1/665	15/18722	0.418820069286674	0.575805185160378	RBP1	1
GO:0018146	keratan sulfate biosynthetic process	1/665	15/18722	0.418820069286674	0.575805185160378	B3GNT7	1
GO:0018410	C-terminal protein amino acid modification	1/665	15/18722	0.418820069286674	0.575805185160378	WIPI2	1
GO:0021542	dentate gyrus development	1/665	15/18722	0.418820069286674	0.575805185160378	PTEN	1
GO:0032239	regulation of nucleobase-containing compound transport	1/665	15/18722	0.418820069286674	0.575805185160378	SETD2	1
GO:0032328	alanine transport	1/665	15/18722	0.418820069286674	0.575805185160378	SLC38A2	1
GO:0032933	SREBP signaling pathway	1/665	15/18722	0.418820069286674	0.575805185160378	INSIG2	1
GO:0033275	actin-myosin filament sliding	1/665	15/18722	0.418820069286674	0.575805185160378	MYL6	1
GO:0033599	regulation of mammary gland epithelial cell proliferation	1/665	15/18722	0.418820069286674	0.575805185160378	GPX1	1
GO:0034310	primary alcohol catabolic process	1/665	15/18722	0.418820069286674	0.575805185160378	ALDH2	1
GO:0034380	high-density lipoprotein particle assembly	1/665	15/18722	0.418820069286674	0.575805185160378	APOE	1
GO:0034638	phosphatidylcholine catabolic process	1/665	15/18722	0.418820069286674	0.575805185160378	APOC1	1
GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	1/665	15/18722	0.418820069286674	0.575805185160378	CITED2	1
GO:0035627	ceramide transport	1/665	15/18722	0.418820069286674	0.575805185160378	PSAP	1
GO:0036124	histone H3-K9 trimethylation	1/665	15/18722	0.418820069286674	0.575805185160378	LMNA	1
GO:0042182	ketone catabolic process	1/665	15/18722	0.418820069286674	0.575805185160378	HAGH	1
GO:0042994	cytoplasmic sequestering of transcription factor	1/665	15/18722	0.418820069286674	0.575805185160378	NFKBIA	1
GO:0043508	negative regulation of JUN kinase activity	1/665	15/18722	0.418820069286674	0.575805185160378	AIDA	1
GO:0044406	adhesion of symbiont to host	1/665	15/18722	0.418820069286674	0.575805185160378	CD81	1
GO:0044793	negative regulation by host of viral process	1/665	15/18722	0.418820069286674	0.575805185160378	ZBED1	1
GO:0045346	regulation of MHC class II biosynthetic process	1/665	15/18722	0.418820069286674	0.575805185160378	SPI1	1
GO:0045836	positive regulation of meiotic nuclear division	1/665	15/18722	0.418820069286674	0.575805185160378	UBE2B	1
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	1/665	15/18722	0.418820069286674	0.575805185160378	RB1	1
GO:0046007	negative regulation of activated T cell proliferation	1/665	15/18722	0.418820069286674	0.575805185160378	PRNP	1
GO:0046184	aldehyde biosynthetic process	1/665	15/18722	0.418820069286674	0.575805185160378	TPI1	1
GO:0046321	positive regulation of fatty acid oxidation	1/665	15/18722	0.418820069286674	0.575805185160378	IRS2	1
GO:0048308	organelle inheritance	1/665	15/18722	0.418820069286674	0.575805185160378	PLK3	1
GO:0048313	Golgi inheritance	1/665	15/18722	0.418820069286674	0.575805185160378	PLK3	1
GO:0048712	negative regulation of astrocyte differentiation	1/665	15/18722	0.418820069286674	0.575805185160378	TREM2	1
GO:0051127	positive regulation of actin nucleation	1/665	15/18722	0.418820069286674	0.575805185160378	GSN	1
GO:0051315	attachment of mitotic spindle microtubules to kinetochore	1/665	15/18722	0.418820069286674	0.575805185160378	RMDN1	1
GO:0051938	L-glutamate import	1/665	15/18722	0.418820069286674	0.575805185160378	SLC1A3	1
GO:0055012	ventricular cardiac muscle cell differentiation	1/665	15/18722	0.418820069286674	0.575805185160378	LMNA	1
GO:0060049	regulation of protein glycosylation	1/665	15/18722	0.418820069286674	0.575805185160378	TMEM59	1
GO:0060253	negative regulation of glial cell proliferation	1/665	15/18722	0.418820069286674	0.575805185160378	TSPO	1
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	1/665	15/18722	0.418820069286674	0.575805185160378	LRRK2	1
GO:0070071	proton-transporting two-sector ATPase complex assembly	1/665	15/18722	0.418820069286674	0.575805185160378	TMEM70	1
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	1/665	15/18722	0.418820069286674	0.575805185160378	CD81	1
GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	1/665	15/18722	0.418820069286674	0.575805185160378	PRNP	1
GO:0072075	metanephric mesenchyme development	1/665	15/18722	0.418820069286674	0.575805185160378	STAT1	1
GO:0072224	metanephric glomerulus development	1/665	15/18722	0.418820069286674	0.575805185160378	EGR1	1
GO:0080154	regulation of fertilization	1/665	15/18722	0.418820069286674	0.575805185160378	LHFPL2	1
GO:0098712	L-glutamate import across plasma membrane	1/665	15/18722	0.418820069286674	0.575805185160378	SLC1A3	1
GO:0099170	postsynaptic modulation of chemical synaptic transmission	1/665	15/18722	0.418820069286674	0.575805185160378	EIF4E	1
GO:0106057	negative regulation of calcineurin-mediated signaling	1/665	15/18722	0.418820069286674	0.575805185160378	PRNP	1
GO:0110156	methylguanosine-cap decapping	1/665	15/18722	0.418820069286674	0.575805185160378	ZFP36	1
GO:1900102	negative regulation of endoplasmic reticulum unfolded protein response	1/665	15/18722	0.418820069286674	0.575805185160378	PPP1R15A	1
GO:1901741	positive regulation of myoblast fusion	1/665	15/18722	0.418820069286674	0.575805185160378	CAPN2	1
GO:1901836	regulation of transcription of nucleolar large rRNA by RNA polymerase I	1/665	15/18722	0.418820069286674	0.575805185160378	NCL	1
GO:1901970	positive regulation of mitotic sister chromatid separation	1/665	15/18722	0.418820069286674	0.575805185160378	RB1	1
GO:1903543	positive regulation of exosomal secretion	1/665	15/18722	0.418820069286674	0.575805185160378	SDCBP	1
GO:1903727	positive regulation of phospholipid metabolic process	1/665	15/18722	0.418820069286674	0.575805185160378	CAPN2	1
GO:1903729	regulation of plasma membrane organization	1/665	15/18722	0.418820069286674	0.575805185160378	GSN	1
GO:1904380	endoplasmic reticulum mannose trimming	1/665	15/18722	0.418820069286674	0.575805185160378	RNF5	1
GO:1904874	positive regulation of telomerase RNA localization to Cajal body	1/665	15/18722	0.418820069286674	0.575805185160378	NOP10	1
GO:1905146	lysosomal protein catabolic process	1/665	15/18722	0.418820069286674	0.575805185160378	VPS13A	1
GO:1905288	vascular associated smooth muscle cell apoptotic process	1/665	15/18722	0.418820069286674	0.575805185160378	SOD2	1
GO:1905459	regulation of vascular associated smooth muscle cell apoptotic process	1/665	15/18722	0.418820069286674	0.575805185160378	SOD2	1
GO:1990169	stress response to copper ion	1/665	15/18722	0.418820069286674	0.575805185160378	MT1X	1
GO:2000052	positive regulation of non-canonical Wnt signaling pathway	1/665	15/18722	0.418820069286674	0.575805185160378	DAB2	1
GO:2000402	negative regulation of lymphocyte migration	1/665	15/18722	0.418820069286674	0.575805185160378	IL27RA	1
GO:2001028	positive regulation of endothelial cell chemotaxis	1/665	15/18722	0.418820069286674	0.575805185160378	VEGFA	1
GO:2001138	regulation of phospholipid transport	1/665	15/18722	0.418820069286674	0.575805185160378	APOE	1
GO:0043547	positive regulation of GTPase activity	10/665	255/18722	0.420313035616187	0.577697949948133	RGS1/LIMS1/S100A10/RAP1A/RAPGEF1/PTK2B/DOCK8/CCL13/AGRN/SIPA1L1	10
GO:0033273	response to vitamin	4/665	93/18722	0.421747802665799	0.579509698437661	SOD2/TSPO/HAMP/EGFR	4
GO:0006513	protein monoubiquitination	3/665	67/18722	0.426966123572095	0.586355798329182	UBE2B/DTX3L/RBX1	3
GO:0043967	histone H4 acetylation	3/665	67/18722	0.426966123572095	0.586355798329182	SPI1/MORF4L1/PER1	3
GO:0006790	sulfur compound metabolic process	13/665	339/18722	0.428821048061592	0.58814765269616	ACSL1/HSD17B4/PAPSS1/CLIC2/IDH1/CLIC1/SLC25A19/PAPSS2/B3GNT7/CHST15/ABHD14B/HAGH/GPX1	13
GO:0035148	tube formation	6/665	148/18722	0.429978013663651	0.58814765269616	VEGFA/ADM/ST14/CITED2/RALA/SETD2	6
GO:0043484	regulation of RNA splicing	6/665	148/18722	0.429978013663651	0.58814765269616	SLC38A2/AHNAK/NCL/LARP7/HNRNPA1/HNRNPH2	6
GO:0044272	sulfur compound biosynthetic process	6/665	148/18722	0.429978013663651	0.58814765269616	ACSL1/PAPSS1/PAPSS2/B3GNT7/CHST15/HAGH	6
GO:0001838	embryonic epithelial tube formation	5/665	121/18722	0.430351045938313	0.58814765269616	ADM/ST14/CITED2/RALA/SETD2	5
GO:0003206	cardiac chamber morphogenesis	5/665	121/18722	0.430351045938313	0.58814765269616	LY6E/CITED2/DHRS3/SMAD7/NRP1	5
GO:0042752	regulation of circadian rhythm	5/665	121/18722	0.430351045938313	0.58814765269616	GNAQ/BHLHE40/KLF10/PPP1CB/PER1	5
GO:0010907	positive regulation of glucose metabolic process	2/665	41/18722	0.430401008622924	0.58814765269616	IRS2/IGF2	2
GO:0031062	positive regulation of histone methylation	2/665	41/18722	0.430401008622924	0.58814765269616	LMNA/JARID2	2
GO:0042307	positive regulation of protein import into nucleus	2/665	41/18722	0.430401008622924	0.58814765269616	FLNA/HCLS1	2
GO:0048286	lung alveolus development	2/665	41/18722	0.430401008622924	0.58814765269616	ERRFI1/PTGES3	2
GO:0048634	regulation of muscle organ development	2/665	41/18722	0.430401008622924	0.58814765269616	YBX3/IGF2	2
GO:0051693	actin filament capping	2/665	41/18722	0.430401008622924	0.58814765269616	CAPG/GSN	2
GO:0060612	adipose tissue development	2/665	41/18722	0.430401008622924	0.58814765269616	ARRDC3/SPI1	2
GO:0071634	regulation of transforming growth factor beta production	2/665	41/18722	0.430401008622924	0.58814765269616	TYROBP/FN1	2
GO:1900371	regulation of purine nucleotide biosynthetic process	2/665	41/18722	0.430401008622924	0.58814765269616	TREM2/ENO1	2
GO:1902116	negative regulation of organelle assembly	2/665	41/18722	0.430401008622924	0.58814765269616	NUPR1/LRRK2	2
GO:1903524	positive regulation of blood circulation	2/665	41/18722	0.430401008622924	0.58814765269616	ADM/RGS2	2
GO:0070588	calcium ion transmembrane transport	12/665	312/18722	0.430750227465844	0.588463065009688	CALM1/ERO1A/CLIC2/AHNAK/CALM3/C4orf3/PTK2B/DIAPH1/ANXA2/ORAI3/ATP2C1/PRNP	12
GO:0016525	negative regulation of angiogenesis	6/665	149/18722	0.436302653146353	0.589372752837494	STAT1/ALOX5/KLF4/PGK1/KLF2/PIK3CB	6
GO:0007585	respiratory gaseous exchange by respiratory system	3/665	68/18722	0.436426828767428	0.589372752837494	NR4A2/MAFB/COX5B	3
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	3/665	68/18722	0.436426828767428	0.589372752837494	TREM2/ALDOA/ENO1	3
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	3/665	68/18722	0.436426828767428	0.589372752837494	PARP9/HCLS1/ARL2BP	3
GO:0051148	negative regulation of muscle cell differentiation	3/665	68/18722	0.436426828767428	0.589372752837494	RGS2/YBX1/IGF2	3
GO:1901016	regulation of potassium ion transmembrane transporter activity	3/665	68/18722	0.436426828767428	0.589372752837494	TREM2/PTEN/KCNE1	3
GO:0045666	positive regulation of neuron differentiation	4/665	95/18722	0.437700065661145	0.589372752837494	PTEN/RHOA/MMD/CXCL12	4
GO:0001574	ganglioside biosynthetic process	1/665	16/18722	0.43947996418828	0.589372752837494	ST8SIA4	1
GO:0001845	phagolysosome assembly	1/665	16/18722	0.43947996418828	0.589372752837494	RAB20	1
GO:0002713	negative regulation of B cell mediated immunity	1/665	16/18722	0.43947996418828	0.589372752837494	FCGR2B	1
GO:0002890	negative regulation of immunoglobulin mediated immune response	1/665	16/18722	0.43947996418828	0.589372752837494	FCGR2B	1
GO:0006740	NADPH regeneration	1/665	16/18722	0.43947996418828	0.589372752837494	PGAM1	1
GO:0006750	glutathione biosynthetic process	1/665	16/18722	0.43947996418828	0.589372752837494	HAGH	1
GO:0010225	response to UV-C	1/665	16/18722	0.43947996418828	0.589372752837494	CARD16	1
GO:0010819	regulation of T cell chemotaxis	1/665	16/18722	0.43947996418828	0.589372752837494	WNK1	1
GO:0014819	regulation of skeletal muscle contraction	1/665	16/18722	0.43947996418828	0.589372752837494	NR4A1	1
GO:0016074	sno(s)RNA metabolic process	1/665	16/18722	0.43947996418828	0.589372752837494	LARP7	1
GO:0016584	nucleosome positioning	1/665	16/18722	0.43947996418828	0.589372752837494	RSF1	1
GO:0019081	viral translation	1/665	16/18722	0.43947996418828	0.589372752837494	SSB	1
GO:0019377	glycolipid catabolic process	1/665	16/18722	0.43947996418828	0.589372752837494	HEXB	1
GO:0021535	cell migration in hindbrain	1/665	16/18722	0.43947996418828	0.589372752837494	FLNA	1
GO:0021783	preganglionic parasympathetic fiber development	1/665	16/18722	0.43947996418828	0.589372752837494	NRP1	1
GO:0030033	microvillus assembly	1/665	16/18722	0.43947996418828	0.589372752837494	FXYD5	1
GO:0030540	female genitalia development	1/665	16/18722	0.43947996418828	0.589372752837494	MERTK	1
GO:0032274	gonadotropin secretion	1/665	16/18722	0.43947996418828	0.589372752837494	CGA	1
GO:0033631	cell-cell adhesion mediated by integrin	1/665	16/18722	0.43947996418828	0.589372752837494	WNK1	1
GO:0034116	positive regulation of heterotypic cell-cell adhesion	1/665	16/18722	0.43947996418828	0.589372752837494	CD44	1
GO:0034374	low-density lipoprotein particle remodeling	1/665	16/18722	0.43947996418828	0.589372752837494	APOE	1
GO:0034393	positive regulation of smooth muscle cell apoptotic process	1/665	16/18722	0.43947996418828	0.589372752837494	SOD2	1
GO:0035067	negative regulation of histone acetylation	1/665	16/18722	0.43947996418828	0.589372752837494	SPI1	1
GO:0042407	cristae formation	1/665	16/18722	0.43947996418828	0.589372752837494	CHCHD3	1
GO:0042574	retinal metabolic process	1/665	16/18722	0.43947996418828	0.589372752837494	CYP1B1	1
GO:0042795	snRNA transcription by RNA polymerase II	1/665	16/18722	0.43947996418828	0.589372752837494	LARP7	1
GO:0043923	positive regulation by host of viral transcription	1/665	16/18722	0.43947996418828	0.589372752837494	JUN	1
GO:0044849	estrous cycle	1/665	16/18722	0.43947996418828	0.589372752837494	EGR1	1
GO:0045838	positive regulation of membrane potential	1/665	16/18722	0.43947996418828	0.589372752837494	GLRX	1
GO:0046037	GMP metabolic process	1/665	16/18722	0.43947996418828	0.589372752837494	GUK1	1
GO:0046135	pyrimidine nucleoside catabolic process	1/665	16/18722	0.43947996418828	0.589372752837494	UPP1	1
GO:0048311	mitochondrion distribution	1/665	16/18722	0.43947996418828	0.589372752837494	LRRK2	1
GO:0050862	positive regulation of T cell receptor signaling pathway	1/665	16/18722	0.43947996418828	0.589372752837494	CD81	1
GO:0051969	regulation of transmission of nerve impulse	1/665	16/18722	0.43947996418828	0.589372752837494	TYMP	1
GO:0055089	fatty acid homeostasis	1/665	16/18722	0.43947996418828	0.589372752837494	APOE	1
GO:0060330	regulation of response to interferon-gamma	1/665	16/18722	0.43947996418828	0.589372752837494	PARP9	1
GO:0060334	regulation of interferon-gamma-mediated signaling pathway	1/665	16/18722	0.43947996418828	0.589372752837494	PARP9	1
GO:0061548	ganglion development	1/665	16/18722	0.43947996418828	0.589372752837494	NRP1	1
GO:0070230	positive regulation of lymphocyte apoptotic process	1/665	16/18722	0.43947996418828	0.589372752837494	ADAM8	1
GO:0070242	thymocyte apoptotic process	1/665	16/18722	0.43947996418828	0.589372752837494	ADAM8	1
GO:0070571	negative regulation of neuron projection regeneration	1/665	16/18722	0.43947996418828	0.589372752837494	PTEN	1
GO:0071501	cellular response to sterol depletion	1/665	16/18722	0.43947996418828	0.589372752837494	INSIG2	1
GO:0072109	glomerular mesangium development	1/665	16/18722	0.43947996418828	0.589372752837494	EGR1	1
GO:0072283	metanephric renal vesicle morphogenesis	1/665	16/18722	0.43947996418828	0.589372752837494	STAT1	1
GO:0080009	mRNA methylation	1/665	16/18722	0.43947996418828	0.589372752837494	ZC3H13	1
GO:0090231	regulation of spindle checkpoint	1/665	16/18722	0.43947996418828	0.589372752837494	DUSP1	1
GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	1/665	16/18722	0.43947996418828	0.589372752837494	DUSP1	1
GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential	1/665	16/18722	0.43947996418828	0.589372752837494	KCNE1	1
GO:0099010	modification of postsynaptic structure	1/665	16/18722	0.43947996418828	0.589372752837494	RHOA	1
GO:0099633	protein localization to postsynaptic specialization membrane	1/665	16/18722	0.43947996418828	0.589372752837494	RAP1A	1
GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	1/665	16/18722	0.43947996418828	0.589372752837494	RAP1A	1
GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway	1/665	16/18722	0.43947996418828	0.589372752837494	PIK3CB	1
GO:1902101	positive regulation of metaphase/anaphase transition of cell cycle	1/665	16/18722	0.43947996418828	0.589372752837494	RB1	1
GO:1902570	protein localization to nucleolus	1/665	16/18722	0.43947996418828	0.589372752837494	GLUL	1
GO:1902931	negative regulation of alcohol biosynthetic process	1/665	16/18722	0.43947996418828	0.589372752837494	APOE	1
GO:1903504	regulation of mitotic spindle checkpoint	1/665	16/18722	0.43947996418828	0.589372752837494	DUSP1	1
GO:1904862	inhibitory synapse assembly	1/665	16/18722	0.43947996418828	0.589372752837494	GABRB2	1
GO:1904948	midbrain dopaminergic neuron differentiation	1/665	16/18722	0.43947996418828	0.589372752837494	NR4A2	1
GO:2000001	regulation of DNA damage checkpoint	1/665	16/18722	0.43947996418828	0.589372752837494	RPA2	1
GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	1/665	16/18722	0.43947996418828	0.589372752837494	DAB2	1
GO:2001224	positive regulation of neuron migration	1/665	16/18722	0.43947996418828	0.589372752837494	FLNA	1
GO:0051648	vesicle localization	7/665	177/18722	0.440703718457223	0.590835126920702	MYO1G/TANC2/BLOC1S1/PTEN/BLOC1S2/LRRK2/KIF5B	7
GO:0007212	dopamine receptor signaling pathway	2/665	42/18722	0.442591383808002	0.590835126920702	FLNA/LRRK2	2
GO:0009124	nucleoside monophosphate biosynthetic process	2/665	42/18722	0.442591383808002	0.590835126920702	UPP1/CMPK1	2
GO:0010591	regulation of lamellipodium assembly	2/665	42/18722	0.442591383808002	0.590835126920702	RAC1/ABI3	2
GO:0014912	negative regulation of smooth muscle cell migration	2/665	42/18722	0.442591383808002	0.590835126920702	RHOA/TRIB1	2
GO:0016601	Rac protein signal transduction	2/665	42/18722	0.442591383808002	0.590835126920702	RAC1/PIK3CB	2
GO:0021879	forebrain neuron differentiation	2/665	42/18722	0.442591383808002	0.590835126920702	B2M/NRP1	2
GO:0030574	collagen catabolic process	2/665	42/18722	0.442591383808002	0.590835126920702	MMP19/MMP14	2
GO:0030808	regulation of nucleotide biosynthetic process	2/665	42/18722	0.442591383808002	0.590835126920702	TREM2/ENO1	2
GO:0032689	negative regulation of interferon-gamma production	2/665	42/18722	0.442591383808002	0.590835126920702	HLA-DRB1/PRNP	2
GO:0045687	positive regulation of glial cell differentiation	2/665	42/18722	0.442591383808002	0.590835126920702	CXCR4/TLR2	2
GO:0046688	response to copper ion	2/665	42/18722	0.442591383808002	0.590835126920702	MT1X/PRNP	2
GO:0055090	acylglycerol homeostasis	2/665	42/18722	0.442591383808002	0.590835126920702	APOE/ANGPTL4	2
GO:0060999	positive regulation of dendritic spine development	2/665	42/18722	0.442591383808002	0.590835126920702	APOE/CAMK1	2
GO:0070328	triglyceride homeostasis	2/665	42/18722	0.442591383808002	0.590835126920702	APOE/ANGPTL4	2
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	2/665	42/18722	0.442591383808002	0.590835126920702	KLF4/RHOA	2
GO:1903432	regulation of TORC1 signaling	2/665	42/18722	0.442591383808002	0.590835126920702	LAMTOR5/RRAGD	2
GO:0015914	phospholipid transport	4/665	96/18722	0.445629345099699	0.59403932052557	APOE/APOC1/PLSCR1/SCARB2	4
GO:0034620	cellular response to unfolded protein	4/665	96/18722	0.445629345099699	0.59403932052557	EIF2AK2/ERO1A/ATF3/PPP1R15A	4
GO:0043648	dicarboxylic acid metabolic process	4/665	96/18722	0.445629345099699	0.59403932052557	GLUL/IDH1/SDHB/KMO	4
GO:0009145	purine nucleoside triphosphate biosynthetic process	3/665	69/18722	0.445828302929653	0.59403932052557	TREM2/ALDOA/ENO1	3
GO:0015807	L-amino acid transport	3/665	69/18722	0.445828302929653	0.59403932052557	SLC11A1/SLC1A3/SLC38A2	3
GO:0019226	transmission of nerve impulse	3/665	69/18722	0.445828302929653	0.59403932052557	TYMP/PLEC/SCN9A	3
GO:0045665	negative regulation of neuron differentiation	3/665	69/18722	0.445828302929653	0.59403932052557	B2M/RHOA/EIF4E	3
GO:0035725	sodium ion transmembrane transport	7/665	178/18722	0.446496635574851	0.594770377595017	YWHAH/SLC6A8/FXYD5/GLRX/WNK1/KIF5B/SCN9A	7
GO:0055067	monovalent inorganic cation homeostasis	6/665	151/18722	0.448912702347131	0.597668398249461	SLC11A1/SLC1A3/RAB20/LRRK2/GRN/KCNMA1	6
GO:2000181	negative regulation of blood vessel morphogenesis	6/665	151/18722	0.448912702347131	0.597668398249461	STAT1/ALOX5/KLF4/PGK1/KLF2/PIK3CB	6
GO:0048863	stem cell differentiation	8/665	206/18722	0.449493143915222	0.598280911960003	ZFP36L2/EIF2AK2/CITED2/KRT18/FN1/JARID2/SETD2/NRP1	8
GO:0014014	negative regulation of gliogenesis	2/665	43/18722	0.454635865407994	0.602758795389389	TREM2/TSPO	2
GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	2/665	43/18722	0.454635865407994	0.602758795389389	FXYD5/ATP2C1	2
GO:0032365	intracellular lipid transport	2/665	43/18722	0.454635865407994	0.602758795389389	PIP4K2A/ANXA2	2
GO:0033173	calcineurin-NFAT signaling cascade	2/665	43/18722	0.454635865407994	0.602758795389389	CLEC7A/PRNP	2
GO:0045776	negative regulation of blood pressure	2/665	43/18722	0.454635865407994	0.602758795389389	SOD2/PTAFR	2
GO:0045840	positive regulation of mitotic nuclear division	2/665	43/18722	0.454635865407994	0.602758795389389	IGF2/RB1	2
GO:0045981	positive regulation of nucleotide metabolic process	2/665	43/18722	0.454635865407994	0.602758795389389	TREM2/ENO1	2
GO:0046717	acid secretion	2/665	43/18722	0.454635865407994	0.602758795389389	SGK1/SNX10	2
GO:0061383	trabecula morphogenesis	2/665	43/18722	0.454635865407994	0.602758795389389	RHOA/FBN2	2
GO:0071604	transforming growth factor beta production	2/665	43/18722	0.454635865407994	0.602758795389389	TYROBP/FN1	2
GO:1900544	positive regulation of purine nucleotide metabolic process	2/665	43/18722	0.454635865407994	0.602758795389389	TREM2/ENO1	2
GO:1904591	positive regulation of protein import	2/665	43/18722	0.454635865407994	0.602758795389389	FLNA/HCLS1	2
GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	2/665	43/18722	0.454635865407994	0.602758795389389	IFI6/MCL1	2
GO:1901343	negative regulation of vasculature development	6/665	152/18722	0.455195250879202	0.602758795389389	STAT1/ALOX5/KLF4/PGK1/KLF2/PIK3CB	6
GO:0051053	negative regulation of DNA metabolic process	5/665	125/18722	0.458241560947091	0.602758795389389	DUSP1/TERF2IP/CDKN1A/ACVRL1/HNRNPA1	5
GO:0001710	mesodermal cell fate commitment	1/665	17/18722	0.45940650240141	0.602758795389389	KLF4	1
GO:0002031	G protein-coupled receptor internalization	1/665	17/18722	0.45940650240141	0.602758795389389	ADM	1
GO:0006895	Golgi to endosome transport	1/665	17/18722	0.45940650240141	0.602758795389389	VPS13A	1
GO:0007379	segment specification	1/665	17/18722	0.45940650240141	0.602758795389389	MAFB	1
GO:0008334	histone mRNA metabolic process	1/665	17/18722	0.45940650240141	0.602758795389389	SSB	1
GO:0008340	determination of adult lifespan	1/665	17/18722	0.45940650240141	0.602758795389389	LRRK2	1
GO:0009084	glutamine family amino acid biosynthetic process	1/665	17/18722	0.45940650240141	0.602758795389389	GLUL	1
GO:0009151	purine deoxyribonucleotide metabolic process	1/665	17/18722	0.45940650240141	0.602758795389389	GUK1	1
GO:0010715	regulation of extracellular matrix disassembly	1/665	17/18722	0.45940650240141	0.602758795389389	PDPN	1
GO:0010831	positive regulation of myotube differentiation	1/665	17/18722	0.45940650240141	0.602758795389389	MMP14	1
GO:0021756	striatum development	1/665	17/18722	0.45940650240141	0.602758795389389	LRRK2	1
GO:0021924	cell proliferation in external granule layer	1/665	17/18722	0.45940650240141	0.602758795389389	ATF5	1
GO:0021930	cerebellar granule cell precursor proliferation	1/665	17/18722	0.45940650240141	0.602758795389389	ATF5	1
GO:0031573	mitotic intra-S DNA damage checkpoint signaling	1/665	17/18722	0.45940650240141	0.602758795389389	XPC	1
GO:0035729	cellular response to hepatocyte growth factor stimulus	1/665	17/18722	0.45940650240141	0.602758795389389	NRP1	1
GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	1/665	17/18722	0.45940650240141	0.602758795389389	PIK3CB	1
GO:0036166	phenotypic switching	1/665	17/18722	0.45940650240141	0.602758795389389	SOD2	1
GO:0038065	collagen-activated signaling pathway	1/665	17/18722	0.45940650240141	0.602758795389389	OSCAR	1
GO:0042339	keratan sulfate metabolic process	1/665	17/18722	0.45940650240141	0.602758795389389	B3GNT7	1
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	1/665	17/18722	0.45940650240141	0.602758795389389	SOCS3	1
GO:0043649	dicarboxylic acid catabolic process	1/665	17/18722	0.45940650240141	0.602758795389389	GLUL	1
GO:0043968	histone H2A acetylation	1/665	17/18722	0.45940650240141	0.602758795389389	MORF4L1	1
GO:0046827	positive regulation of protein export from nucleus	1/665	17/18722	0.45940650240141	0.602758795389389	CAMK1	1
GO:0046855	inositol phosphate dephosphorylation	1/665	17/18722	0.45940650240141	0.602758795389389	PTEN	1
GO:0048521	negative regulation of behavior	1/665	17/18722	0.45940650240141	0.602758795389389	ARRDC3	1
GO:0048532	anatomical structure arrangement	1/665	17/18722	0.45940650240141	0.602758795389389	NRP1	1
GO:0060033	anatomical structure regression	1/665	17/18722	0.45940650240141	0.602758795389389	SPI1	1
GO:0060644	mammary gland epithelial cell differentiation	1/665	17/18722	0.45940650240141	0.602758795389389	CEBPB	1
GO:0061952	midbody abscission	1/665	17/18722	0.45940650240141	0.602758795389389	CHMP5	1
GO:0071816	tail-anchored membrane protein insertion into ER membrane	1/665	17/18722	0.45940650240141	0.602758795389389	CAMLG	1
GO:0090083	regulation of inclusion body assembly	1/665	17/18722	0.45940650240141	0.602758795389389	PSMC6	1
GO:0090136	epithelial cell-cell adhesion	1/665	17/18722	0.45940650240141	0.602758795389389	CYP1B1	1
GO:0090399	replicative senescence	1/665	17/18722	0.45940650240141	0.602758795389389	CDKN1A	1
GO:1900034	regulation of cellular response to heat	1/665	17/18722	0.45940650240141	0.602758795389389	IER5	1
GO:1901550	regulation of endothelial cell development	1/665	17/18722	0.45940650240141	0.602758795389389	VEGFA	1
GO:1903140	regulation of establishment of endothelial barrier	1/665	17/18722	0.45940650240141	0.602758795389389	VEGFA	1
GO:1903541	regulation of exosomal secretion	1/665	17/18722	0.45940650240141	0.602758795389389	SDCBP	1
GO:1903818	positive regulation of voltage-gated potassium channel activity	1/665	17/18722	0.45940650240141	0.602758795389389	TREM2	1
GO:2000811	negative regulation of anoikis	1/665	17/18722	0.45940650240141	0.602758795389389	MCL1	1
GO:0007204	positive regulation of cytosolic calcium ion concentration	12/665	319/18722	0.461167577252514	0.604870843348226	CXCR4/FPR3/CALM1/ERO1A/ADM/C5AR1/CD36/CLIC2/CALM3/PTK2B/DIAPH1/PRNP	12
GO:0003333	amino acid transmembrane transport	4/665	98/18722	0.461381361596202	0.604870843348226	SLC1A3/SLC38A2/RGS2/SLC16A10	4
GO:0061337	cardiac conduction	4/665	98/18722	0.461381361596202	0.604870843348226	CALM1/FLNA/KCNE1/CALM3	4
GO:0150063	visual system development	14/665	375/18722	0.463025250721096	0.606865900865993	VIM/VEGFA/KLF4/MERTK/SKIL/SCO2/CITED2/ITGAM/FBN2/ACVRL1/EPHB2/CYP1B1/C1QA/NRP1	14
GO:0099504	synaptic vesicle cycle	7/665	181/18722	0.463807082803456	0.607730345777267	CALM1/RAP1A/FCHO2/PTEN/LRRK2/CALM3/STX3	7
GO:0008344	adult locomotory behavior	3/665	71/18722	0.464438761346654	0.608397639402444	NR4A2/CSTB/CXCL12	3
GO:0016042	lipid catabolic process	12/665	320/18722	0.465498915412107	0.609625720579229	APOE/APOC1/YWHAH/HSD17B4/IRS2/HSD17B11/IDH1/GPCPD1/PLBD1/HEXB/CYP1B1/ABHD5	12
GO:0006775	fat-soluble vitamin metabolic process	2/665	44/18722	0.466529429815356	0.610331999521536	RBP1/VKORC1	2
GO:0007528	neuromuscular junction development	2/665	44/18722	0.466529429815356	0.610331999521536	LRRK2/AGRN	2
GO:0032007	negative regulation of TOR signaling	2/665	44/18722	0.466529429815356	0.610331999521536	DDIT4/AKT1S1	2
GO:0089718	amino acid import across plasma membrane	2/665	44/18722	0.466529429815356	0.610331999521536	SLC1A3/RGS2	2
GO:0051168	nuclear export	6/665	154/18722	0.467708465198309	0.611713440009368	IFI27/SSB/TXN/CAMK1/HNRNPA1/SETD2	6
GO:0051153	regulation of striated muscle cell differentiation	4/665	99/18722	0.469199235361361	0.613501762627194	HAMP/RGS2/YBX1/MMP14	4
GO:0060401	cytosolic calcium ion transport	7/665	182/18722	0.469550807853049	0.613799977651145	CALM1/ERO1A/CLIC2/CALM3/PTK2B/DIAPH1/PRNP	7
GO:0035270	endocrine system development	5/665	127/18722	0.472044009074564	0.615980862116415	TSPO/LY6E/CGA/CITED2/ANXA1	5
GO:0030032	lamellipodium assembly	3/665	72/18722	0.473640839125716	0.615980862116415	RAC1/PARVB/ABI3	3
GO:0033627	cell adhesion mediated by integrin	3/665	72/18722	0.473640839125716	0.615980862116415	WNK1/PLAU/CYP1B1	3
GO:0050709	negative regulation of protein secretion	3/665	72/18722	0.473640839125716	0.615980862116415	APOE/RSAD2/ANXA1	3
GO:1905818	regulation of chromosome separation	3/665	72/18722	0.473640839125716	0.615980862116415	DUSP1/PLSCR1/RB1	3
GO:0046474	glycerophospholipid biosynthetic process	8/665	211/18722	0.476274156663195	0.615980862116415	CAPN2/PLSCR1/PIP4K2A/PTEN/SOCS3/AGPAT2/PIK3CB/ABHD5	8
GO:0003197	endocardial cushion development	2/665	45/18722	0.478267593060684	0.615980862116415	CITED2/ACVRL1	2
GO:0030835	negative regulation of actin filament depolymerization	2/665	45/18722	0.478267593060684	0.615980862116415	CAPG/GSN	2
GO:0035272	exocrine system development	2/665	45/18722	0.478267593060684	0.615980862116415	IGF2/NRP1	2
GO:0035305	negative regulation of dephosphorylation	2/665	45/18722	0.478267593060684	0.615980862116415	PPP1R15A/LGALS3	2
GO:0048599	oocyte development	2/665	45/18722	0.478267593060684	0.615980862116415	ANG/PTK2B	2
GO:1901985	positive regulation of protein acetylation	2/665	45/18722	0.478267593060684	0.615980862116415	TERF2IP/CAMK1	2
GO:0001522	pseudouridine synthesis	1/665	18/18722	0.478625677803872	0.615980862116415	NOP10	1
GO:0001956	positive regulation of neurotransmitter secretion	1/665	18/18722	0.478625677803872	0.615980862116415	KMO	1
GO:0002076	osteoblast development	1/665	18/18722	0.478625677803872	0.615980862116415	JUND	1
GO:0002643	regulation of tolerance induction	1/665	18/18722	0.478625677803872	0.615980862116415	HLA-B	1
GO:0006103	2-oxoglutarate metabolic process	1/665	18/18722	0.478625677803872	0.615980862116415	IDH1	1
GO:0006595	polyamine metabolic process	1/665	18/18722	0.478625677803872	0.615980862116415	OAZ1	1
GO:0006957	complement activation, alternative pathway	1/665	18/18722	0.478625677803872	0.615980862116415	CFD	1
GO:0006991	response to sterol depletion	1/665	18/18722	0.478625677803872	0.615980862116415	INSIG2	1
GO:0009404	toxin metabolic process	1/665	18/18722	0.478625677803872	0.615980862116415	CYP1B1	1
GO:0010985	negative regulation of lipoprotein particle clearance	1/665	18/18722	0.478625677803872	0.615980862116415	APOC1	1
GO:0019184	nonribosomal peptide biosynthetic process	1/665	18/18722	0.478625677803872	0.615980862116415	HAGH	1
GO:0030206	chondroitin sulfate biosynthetic process	1/665	18/18722	0.478625677803872	0.615980862116415	CHST15	1
GO:0030299	intestinal cholesterol absorption	1/665	18/18722	0.478625677803872	0.615980862116415	CD36	1
GO:0030728	ovulation	1/665	18/18722	0.478625677803872	0.615980862116415	RGS2	1
GO:0031649	heat generation	1/665	18/18722	0.478625677803872	0.615980862116415	ARRDC3	1
GO:0032634	interleukin-5 production	1/665	18/18722	0.478625677803872	0.615980862116415	IL1RAP	1
GO:0032674	regulation of interleukin-5 production	1/665	18/18722	0.478625677803872	0.615980862116415	IL1RAP	1
GO:0033189	response to vitamin A	1/665	18/18722	0.478625677803872	0.615980862116415	HAMP	1
GO:0036499	PERK-mediated unfolded protein response	1/665	18/18722	0.478625677803872	0.615980862116415	PPP1R15A	1
GO:0036507	protein demannosylation	1/665	18/18722	0.478625677803872	0.615980862116415	RNF5	1
GO:0036508	protein alpha-1,2-demannosylation	1/665	18/18722	0.478625677803872	0.615980862116415	RNF5	1
GO:0042790	nucleolar large rRNA transcription by RNA polymerase I	1/665	18/18722	0.478625677803872	0.615980862116415	NCL	1
GO:0046112	nucleobase biosynthetic process	1/665	18/18722	0.478625677803872	0.615980862116415	CMPK1	1
GO:0046838	phosphorylated carbohydrate dephosphorylation	1/665	18/18722	0.478625677803872	0.615980862116415	PTEN	1
GO:0048268	clathrin coat assembly	1/665	18/18722	0.478625677803872	0.615980862116415	FCHO2	1
GO:0048486	parasympathetic nervous system development	1/665	18/18722	0.478625677803872	0.615980862116415	NRP1	1
GO:0048643	positive regulation of skeletal muscle tissue development	1/665	18/18722	0.478625677803872	0.615980862116415	IGF2	1
GO:0050665	hydrogen peroxide biosynthetic process	1/665	18/18722	0.478625677803872	0.615980862116415	SOD2	1
GO:0051447	negative regulation of meiotic cell cycle	1/665	18/18722	0.478625677803872	0.615980862116415	DUSP1	1
GO:0051782	negative regulation of cell division	1/665	18/18722	0.478625677803872	0.615980862116415	TXNIP	1
GO:0060391	positive regulation of SMAD protein signal transduction	1/665	18/18722	0.478625677803872	0.615980862116415	DAB2	1
GO:0060546	negative regulation of necroptotic process	1/665	18/18722	0.478625677803872	0.615980862116415	YBX3	1
GO:0060716	labyrinthine layer blood vessel development	1/665	18/18722	0.478625677803872	0.615980862116415	JUNB	1
GO:0060749	mammary gland alveolus development	1/665	18/18722	0.478625677803872	0.615980862116415	VEGFA	1
GO:0061377	mammary gland lobule development	1/665	18/18722	0.478625677803872	0.615980862116415	VEGFA	1
GO:0061687	detoxification of inorganic compound	1/665	18/18722	0.478625677803872	0.615980862116415	MT1X	1
GO:0071786	endoplasmic reticulum tubular network organization	1/665	18/18722	0.478625677803872	0.615980862116415	RTN3	1
GO:0072234	metanephric nephron tubule development	1/665	18/18722	0.478625677803872	0.615980862116415	STAT1	1
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	1/665	18/18722	0.478625677803872	0.615980862116415	VEGFA	1
GO:0097709	connective tissue replacement	1/665	18/18722	0.478625677803872	0.615980862116415	TIMP1	1
GO:0110154	RNA decapping	1/665	18/18722	0.478625677803872	0.615980862116415	ZFP36	1
GO:1900424	regulation of defense response to bacterium	1/665	18/18722	0.478625677803872	0.615980862116415	GRN	1
GO:1901673	regulation of mitotic spindle assembly	1/665	18/18722	0.478625677803872	0.615980862116415	CHMP5	1
GO:1902074	response to salt	1/665	18/18722	0.478625677803872	0.615980862116415	HNRNPA1	1
GO:1902548	negative regulation of cellular response to vascular endothelial growth factor stimulus	1/665	18/18722	0.478625677803872	0.615980862116415	PIK3CB	1
GO:1903209	positive regulation of oxidative stress-induced cell death	1/665	18/18722	0.478625677803872	0.615980862116415	MCL1	1
GO:1904872	regulation of telomerase RNA localization to Cajal body	1/665	18/18722	0.478625677803872	0.615980862116415	NOP10	1
GO:0033865	nucleoside bisphosphate metabolic process	5/665	128/18722	0.478903430828536	0.615980862116415	ACSL1/HSD17B4/PAPSS1/PAPSS2/ABHD14B	5
GO:0033875	ribonucleoside bisphosphate metabolic process	5/665	128/18722	0.478903430828536	0.615980862116415	ACSL1/HSD17B4/PAPSS1/PAPSS2/ABHD14B	5
GO:0034032	purine nucleoside bisphosphate metabolic process	5/665	128/18722	0.478903430828536	0.615980862116415	ACSL1/HSD17B4/PAPSS1/PAPSS2/ABHD14B	5
GO:0055001	muscle cell development	7/665	184/18722	0.480992250972738	0.618507499957182	VEGFA/ADM/HAMP/RGS2/LMNA/PLEC/GPX1	7
GO:0048193	Golgi vesicle transport	11/665	296/18722	0.482595268081636	0.619991272601382	RAB8A/VAMP5/GABARAPL2/GOLGA7/CNIH4/KRT18/LRRK2/RAB13/RAB31/VPS13A/ATP2C1	11
GO:0045739	positive regulation of DNA repair	3/665	73/18722	0.482769864178541	0.619991272601382	DTX3L/PARP9/EGFR	3
GO:0051145	smooth muscle cell differentiation	3/665	73/18722	0.482769864178541	0.619991272601382	VEGFA/ADM/SOD2	3
GO:0070988	demethylation	3/665	73/18722	0.482769864178541	0.619991272601382	UBE2B/KDM1B/JARID2	3
GO:0086003	cardiac muscle cell contraction	3/665	73/18722	0.482769864178541	0.619991272601382	GSN/FLNA/KCNE1	3
GO:0007498	mesoderm development	5/665	129/18722	0.485732792765519	0.623635231217936	VEGFA/KLF4/CITED2/GPI/SETD2	5
GO:0048880	sensory system development	14/665	381/18722	0.486958130685128	0.625046980760611	VIM/VEGFA/KLF4/MERTK/SKIL/SCO2/CITED2/ITGAM/FBN2/ACVRL1/EPHB2/CYP1B1/C1QA/NRP1	14
GO:0001974	blood vessel remodeling	2/665	46/18722	0.489846378917329	0.627296187379316	FLNA/ACVRL1	2
GO:0006984	ER-nucleus signaling pathway	2/665	46/18722	0.489846378917329	0.627296187379316	PPP1R15A/INSIG2	2
GO:0010828	positive regulation of glucose transmembrane transport	2/665	46/18722	0.489846378917329	0.627296187379316	IRS2/RAP1A	2
GO:0035094	response to nicotine	2/665	46/18722	0.489846378917329	0.627296187379316	B2M/HMOX1	2
GO:0043616	keratinocyte proliferation	2/665	46/18722	0.489846378917329	0.627296187379316	ZFP36/KLF9	2
GO:0044818	mitotic G2/M transition checkpoint	2/665	46/18722	0.489846378917329	0.627296187379316	CDKN1A/FOXN3	2
GO:0048701	embryonic cranial skeleton morphogenesis	2/665	46/18722	0.489846378917329	0.627296187379316	MMP14/SETD2	2
GO:0055010	ventricular cardiac muscle tissue morphogenesis	2/665	46/18722	0.489846378917329	0.627296187379316	LY6E/SMAD7	2
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	2/665	46/18722	0.489846378917329	0.627296187379316	ANXA1/EGFR	2
GO:0015711	organic anion transport	13/665	354/18722	0.491147360304462	0.628800201111071	SLC11A1/SLC6A8/SLC16A3/SLC1A3/CD36/SLC38A2/SLC2A3/ANXA1/SLC25A19/RGS2/ABCC3/KMO/PSAP	13
GO:0009201	ribonucleoside triphosphate biosynthetic process	3/665	74/18722	0.491822855332874	0.629178787903316	TREM2/ALDOA/ENO1	3
GO:0048332	mesoderm morphogenesis	3/665	74/18722	0.491822855332874	0.629178787903316	KLF4/GPI/SETD2	3
GO:1901568	fatty acid derivative metabolic process	3/665	74/18722	0.491822855332874	0.629178787903316	ALOX5/ACSL1/HSD17B4	3
GO:0034308	primary alcohol metabolic process	4/665	102/18722	0.492393024117576	0.629207523393995	ALDH2/DHRS3/CYP1B1/ALDH3A2	4
GO:0045833	negative regulation of lipid metabolic process	4/665	102/18722	0.492393024117576	0.629207523393995	APOE/APOC1/PIP4K2A/INSIG2	4
GO:0051028	mRNA transport	5/665	130/18722	0.49253051330226	0.629207523393995	MX2/ZFP36/NUP58/HNRNPA1/SETD2	5
GO:0006644	phospholipid metabolic process	14/665	383/18722	0.494894507667463	0.629207523393995	CAPN2/APOC1/PLSCR1/PIP4K2A/IDH1/PTEN/SOCS3/GPCPD1/SERINC1/PLBD1/AGPAT2/PIK3CB/HEXB/ABHD5	14
GO:0000028	ribosomal small subunit assembly	1/665	19/18722	0.497162564259199	0.629207523393995	RPS27L	1
GO:0003085	negative regulation of systemic arterial blood pressure	1/665	19/18722	0.497162564259199	0.629207523393995	SOD2	1
GO:0006071	glycerol metabolic process	1/665	19/18722	0.497162564259199	0.629207523393995	TPI1	1
GO:0006491	N-glycan processing	1/665	19/18722	0.497162564259199	0.629207523393995	ST8SIA4	1
GO:0007530	sex determination	1/665	19/18722	0.497162564259199	0.629207523393995	CITED2	1
GO:0007603	phototransduction, visible light	1/665	19/18722	0.497162564259199	0.629207523393995	GNAQ	1
GO:0010759	positive regulation of macrophage chemotaxis	1/665	19/18722	0.497162564259199	0.629207523393995	C5AR1	1
GO:0010829	negative regulation of glucose transmembrane transport	1/665	19/18722	0.497162564259199	0.629207523393995	PEA15	1
GO:0015802	basic amino acid transport	1/665	19/18722	0.497162564259199	0.629207523393995	SLC11A1	1
GO:0019373	epoxygenase P450 pathway	1/665	19/18722	0.497162564259199	0.629207523393995	CYP1B1	1
GO:0030050	vesicle transport along actin filament	1/665	19/18722	0.497162564259199	0.629207523393995	MYO1G	1
GO:0032026	response to magnesium ion	1/665	19/18722	0.497162564259199	0.629207523393995	FBP1	1
GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	1/665	19/18722	0.497162564259199	0.629207523393995	ACSL1	1
GO:0035461	vitamin transmembrane transport	1/665	19/18722	0.497162564259199	0.629207523393995	SLC25A19	1
GO:0035728	response to hepatocyte growth factor	1/665	19/18722	0.497162564259199	0.629207523393995	NRP1	1
GO:0038092	nodal signaling pathway	1/665	19/18722	0.497162564259199	0.629207523393995	CITED2	1
GO:0042474	middle ear morphogenesis	1/665	19/18722	0.497162564259199	0.629207523393995	INSIG2	1
GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate	1/665	19/18722	0.497162564259199	0.629207523393995	CXCL8	1
GO:0045947	negative regulation of translational initiation	1/665	19/18722	0.497162564259199	0.629207523393995	EIF4EBP1	1
GO:0046716	muscle cell cellular homeostasis	1/665	19/18722	0.497162564259199	0.629207523393995	ALDOA	1
GO:0051546	keratinocyte migration	1/665	19/18722	0.497162564259199	0.629207523393995	PTEN	1
GO:0051957	positive regulation of amino acid transport	1/665	19/18722	0.497162564259199	0.629207523393995	KMO	1
GO:0060039	pericardium development	1/665	19/18722	0.497162564259199	0.629207523393995	SETD2	1
GO:0060216	definitive hemopoiesis	1/665	19/18722	0.497162564259199	0.629207523393995	ZFP36L2	1
GO:0071545	inositol phosphate catabolic process	1/665	19/18722	0.497162564259199	0.629207523393995	PTEN	1
GO:0072074	kidney mesenchyme development	1/665	19/18722	0.497162564259199	0.629207523393995	STAT1	1
GO:0072077	renal vesicle morphogenesis	1/665	19/18722	0.497162564259199	0.629207523393995	STAT1	1
GO:0086014	atrial cardiac muscle cell action potential	1/665	19/18722	0.497162564259199	0.629207523393995	FLNA	1
GO:0086026	atrial cardiac muscle cell to AV node cell signaling	1/665	19/18722	0.497162564259199	0.629207523393995	FLNA	1
GO:0086066	atrial cardiac muscle cell to AV node cell communication	1/665	19/18722	0.497162564259199	0.629207523393995	FLNA	1
GO:0090670	RNA localization to Cajal body	1/665	19/18722	0.497162564259199	0.629207523393995	NOP10	1
GO:0090671	telomerase RNA localization to Cajal body	1/665	19/18722	0.497162564259199	0.629207523393995	NOP10	1
GO:0090672	telomerase RNA localization	1/665	19/18722	0.497162564259199	0.629207523393995	NOP10	1
GO:0090685	RNA localization to nucleus	1/665	19/18722	0.497162564259199	0.629207523393995	NOP10	1
GO:0097501	stress response to metal ion	1/665	19/18722	0.497162564259199	0.629207523393995	MT1X	1
GO:0097623	potassium ion export across plasma membrane	1/665	19/18722	0.497162564259199	0.629207523393995	KCNE1	1
GO:1901739	regulation of myoblast fusion	1/665	19/18722	0.497162564259199	0.629207523393995	CAPN2	1
GO:2000269	regulation of fibroblast apoptotic process	1/665	19/18722	0.497162564259199	0.629207523393995	BTG1	1
GO:0000723	telomere maintenance	5/665	131/18722	0.499295060524495	0.631341503869606	TERF2IP/NOP10/PTGES3/RPA2/HNRNPA1	5
GO:0002027	regulation of heart rate	4/665	103/18722	0.500030611666195	0.631341503869606	CALM1/ADM/KCNE1/CALM3	4
GO:0003279	cardiac septum development	4/665	103/18722	0.500030611666195	0.631341503869606	CITED2/DHRS3/SMAD7/NRP1	4
GO:0019233	sensory perception of pain	4/665	103/18722	0.500030611666195	0.631341503869606	CXCR4/PTAFR/SCN9A/CXCL12	4
GO:0046425	regulation of receptor signaling pathway via JAK-STAT	4/665	103/18722	0.500030611666195	0.631341503869606	CD300A/SOCS3/PTK2B/CYP1B1	4
GO:0045913	positive regulation of carbohydrate metabolic process	3/665	75/18722	0.50079701201838	0.631341503869606	IRS2/PTAFR/IGF2	3
GO:0010761	fibroblast migration	2/665	47/18722	0.501262288585405	0.631341503869606	RAC1/PLEC	2
GO:0016073	snRNA metabolic process	2/665	47/18722	0.501262288585405	0.631341503869606	NOP10/LARP7	2
GO:0016574	histone ubiquitination	2/665	47/18722	0.501262288585405	0.631341503869606	UBE2B/DTX3L	2
GO:0031641	regulation of myelination	2/665	47/18722	0.501262288585405	0.631341503869606	TYMP/PTEN	2
GO:0032369	negative regulation of lipid transport	2/665	47/18722	0.501262288585405	0.631341503869606	APOC1/IRS2	2
GO:0035850	epithelial cell differentiation involved in kidney development	2/665	47/18722	0.501262288585405	0.631341503869606	STAT1/PRKX	2
GO:0045911	positive regulation of DNA recombination	2/665	47/18722	0.501262288585405	0.631341503869606	UBE2B/TFRC	2
GO:0048483	autonomic nervous system development	2/665	47/18722	0.501262288585405	0.631341503869606	FN1/NRP1	2
GO:0048512	circadian behavior	2/665	47/18722	0.501262288585405	0.631341503869606	PTEN/EGR1	2
GO:0050885	neuromuscular process controlling balance	2/665	47/18722	0.501262288585405	0.631341503869606	SLC1A3/HEXB	2
GO:0051972	regulation of telomerase activity	2/665	47/18722	0.501262288585405	0.631341503869606	KLF4/PTGES3	2
GO:0097300	programmed necrotic cell death	2/665	47/18722	0.501262288585405	0.631341503869606	NUPR1/YBX3	2
GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	2/665	47/18722	0.501262288585405	0.631341503869606	VEGFA/HMOX1	2
GO:0030198	extracellular matrix organization	11/665	301/18722	0.504995252332083	0.635882038026464	ADAM8/SULF2/P4HA1/ERO1A/MMP19/PDPN/MMP14/TGFBI/ANXA2/RB1/CYP1B1	11
GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	10/665	273/18722	0.505875085685598	0.63682856531343	ALCAM/JAML/KLF4/IL1RAP/FXYD5/MYADM/CADM1/ITGAM/WNK1/ATP2C1	10
GO:0072175	epithelial tube formation	5/665	132/18722	0.506024952097501	0.636855915908984	ADM/ST14/CITED2/RALA/SETD2	5
GO:0098656	anion transmembrane transport	9/665	245/18722	0.506860619398479	0.637746146433023	SLC6A8/SLC16A3/SLC1A3/CLIC2/SLC25A19/RGS2/GABRB2/PTAFR/PRNP	9
GO:0043062	extracellular structure organization	11/665	302/18722	0.509445688327641	0.639758310907741	ADAM8/SULF2/P4HA1/ERO1A/MMP19/PDPN/MMP14/TGFBI/ANXA2/RB1/CYP1B1	11
GO:0006305	DNA alkylation	3/665	76/18722	0.509689709583423	0.639758310907741	FOS/SPI1/KDM1B	3
GO:0006306	DNA methylation	3/665	76/18722	0.509689709583423	0.639758310907741	FOS/SPI1/KDM1B	3
GO:0014855	striated muscle cell proliferation	3/665	76/18722	0.509689709583423	0.639758310907741	CITED2/PTEN/JARID2	3
GO:0032543	mitochondrial translation	3/665	76/18722	0.509689709583423	0.639758310907741	MRPS18B/GATC/MRPL43	3
GO:0045685	regulation of glial cell differentiation	3/665	76/18722	0.509689709583423	0.639758310907741	CXCR4/TREM2/TLR2	3
GO:0140029	exocytic process	3/665	76/18722	0.509689709583423	0.639758310907741	RAB8A/STX3/RAB13	3
GO:0140115	export across plasma membrane	3/665	76/18722	0.509689709583423	0.639758310907741	CALM1/KCNE1/CALM3	3
GO:0051650	establishment of vesicle localization	6/665	161/18722	0.510823989733855	0.639758310907741	MYO1G/TANC2/BLOC1S1/BLOC1S2/LRRK2/KIF5B	6
GO:0015804	neutral amino acid transport	2/665	48/18722	0.51251227188352	0.639758310907741	SLC38A2/RGS2	2
GO:0035036	sperm-egg recognition	2/665	48/18722	0.51251227188352	0.639758310907741	CD9/ALDOA	2
GO:0042149	cellular response to glucose starvation	2/665	48/18722	0.51251227188352	0.639758310907741	UPP1/HNRNPA1	2
GO:0043303	mast cell degranulation	2/665	48/18722	0.51251227188352	0.639758310907741	CD300A/HMOX1	2
GO:0061647	histone H3-K9 modification	2/665	48/18722	0.51251227188352	0.639758310907741	LMNA/JARID2	2
GO:0090311	regulation of protein deacetylation	2/665	48/18722	0.51251227188352	0.639758310907741	VEGFA/LRRK2	2
GO:0097720	calcineurin-mediated signaling	2/665	48/18722	0.51251227188352	0.639758310907741	CLEC7A/PRNP	2
GO:0120009	intermembrane lipid transfer	2/665	48/18722	0.51251227188352	0.639758310907741	APOE/TSPO	2
GO:1903053	regulation of extracellular matrix organization	2/665	48/18722	0.51251227188352	0.639758310907741	PDPN/RB1	2
GO:0051216	cartilage development	7/665	190/18722	0.514876528025216	0.639758310907741	SULF2/TIMP1/ECM1/CD44/ACVRL1/TGFBI/SMAD7	7
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	1/665	20/18722	0.515041348131713	0.639758310907741	RB1	1
GO:0001832	blastocyst growth	1/665	20/18722	0.515041348131713	0.639758310907741	COPS2	1
GO:0006448	regulation of translational elongation	1/665	20/18722	0.515041348131713	0.639758310907741	CPEB2	1
GO:0006525	arginine metabolic process	1/665	20/18722	0.515041348131713	0.639758310907741	DDAH2	1
GO:0006607	NLS-bearing protein import into nucleus	1/665	20/18722	0.515041348131713	0.639758310907741	KPNA3	1
GO:0006883	cellular sodium ion homeostasis	1/665	20/18722	0.515041348131713	0.639758310907741	SLC1A3	1
GO:0009713	catechol-containing compound biosynthetic process	1/665	20/18722	0.515041348131713	0.639758310907741	NR4A2	1
GO:0014047	glutamate secretion	1/665	20/18722	0.515041348131713	0.639758310907741	KMO	1
GO:0015669	gas transport	1/665	20/18722	0.515041348131713	0.639758310907741	HBG1	1
GO:0017121	plasma membrane phospholipid scrambling	1/665	20/18722	0.515041348131713	0.639758310907741	PLSCR1	1
GO:0030150	protein import into mitochondrial matrix	1/665	20/18722	0.515041348131713	0.639758310907741	DNAJC15	1
GO:0031645	negative regulation of nervous system process	1/665	20/18722	0.515041348131713	0.639758310907741	PTEN	1
GO:0032211	negative regulation of telomere maintenance via telomerase	1/665	20/18722	0.515041348131713	0.639758310907741	HNRNPA1	1
GO:0032793	positive regulation of CREB transcription factor activity	1/665	20/18722	0.515041348131713	0.639758310907741	VEGFA	1
GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate	1/665	20/18722	0.515041348131713	0.639758310907741	CXCL8	1
GO:0042423	catecholamine biosynthetic process	1/665	20/18722	0.515041348131713	0.639758310907741	NR4A2	1
GO:0043011	myeloid dendritic cell differentiation	1/665	20/18722	0.515041348131713	0.639758310907741	SPI1	1
GO:0043046	DNA methylation involved in gamete generation	1/665	20/18722	0.515041348131713	0.639758310907741	KDM1B	1
GO:0043586	tongue development	1/665	20/18722	0.515041348131713	0.639758310907741	EGFR	1
GO:0043651	linoleic acid metabolic process	1/665	20/18722	0.515041348131713	0.639758310907741	ALOX5	1
GO:0043691	reverse cholesterol transport	1/665	20/18722	0.515041348131713	0.639758310907741	APOE	1
GO:0045844	positive regulation of striated muscle tissue development	1/665	20/18722	0.515041348131713	0.639758310907741	IGF2	1
GO:0046629	gamma-delta T cell activation	1/665	20/18722	0.515041348131713	0.639758310907741	JAML	1
GO:0048636	positive regulation of muscle organ development	1/665	20/18722	0.515041348131713	0.639758310907741	IGF2	1
GO:0060231	mesenchymal to epithelial transition	1/665	20/18722	0.515041348131713	0.639758310907741	STAT1	1
GO:0070166	enamel mineralization	1/665	20/18722	0.515041348131713	0.639758310907741	FAM20C	1
GO:0070932	histone H3 deacetylation	1/665	20/18722	0.515041348131713	0.639758310907741	PER1	1
GO:0072087	renal vesicle development	1/665	20/18722	0.515041348131713	0.639758310907741	STAT1	1
GO:0097503	sialylation	1/665	20/18722	0.515041348131713	0.639758310907741	ST8SIA4	1
GO:1903817	negative regulation of voltage-gated potassium channel activity	1/665	20/18722	0.515041348131713	0.639758310907741	KCNE1	1
GO:1990182	exosomal secretion	1/665	20/18722	0.515041348131713	0.639758310907741	SDCBP	1
GO:2000757	negative regulation of peptidyl-lysine acetylation	1/665	20/18722	0.515041348131713	0.639758310907741	SPI1	1
GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	4/665	105/18722	0.515153472887883	0.639758310907741	RAC1/RALA/AGRN/NRP1	4
GO:0051494	negative regulation of cytoskeleton organization	6/665	162/18722	0.516880781130629	0.641743063257363	CAPG/MYADM/GSN/GMFG/MAPRE1/TMSB10	6
GO:0045229	external encapsulating structure organization	11/665	304/18722	0.518313044020501	0.643360596598874	ADAM8/SULF2/P4HA1/ERO1A/MMP19/PDPN/MMP14/TGFBI/ANXA2/RB1/CYP1B1	11
GO:1901983	regulation of protein acetylation	3/665	77/18722	0.518498494562116	0.643430091878581	TERF2IP/SPI1/CAMK1	3
GO:0006164	purine nucleotide biosynthetic process	7/665	191/18722	0.520449788422325	0.645690326624802	TREM2/ALDOA/ACSL1/PAPSS1/ENO1/PAPSS2/GUK1	7
GO:0006766	vitamin metabolic process	4/665	106/18722	0.522635112576872	0.647668682404004	SLC2A3/SLC25A19/RBP1/VKORC1	4
GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	2/665	49/18722	0.52359369987961	0.647668682404004	IL27RA/TFRC	2
GO:0002208	somatic diversification of immunoglobulins involved in immune response	2/665	49/18722	0.52359369987961	0.647668682404004	IL27RA/TFRC	2
GO:0002279	mast cell activation involved in immune response	2/665	49/18722	0.52359369987961	0.647668682404004	CD300A/HMOX1	2
GO:0007622	rhythmic behavior	2/665	49/18722	0.52359369987961	0.647668682404004	PTEN/EGR1	2
GO:0009994	oocyte differentiation	2/665	49/18722	0.52359369987961	0.647668682404004	ANG/PTK2B	2
GO:0045190	isotype switching	2/665	49/18722	0.52359369987961	0.647668682404004	IL27RA/TFRC	2
GO:0046605	regulation of centrosome cycle	2/665	49/18722	0.52359369987961	0.647668682404004	ATF5/CHMP5	2
GO:0051445	regulation of meiotic cell cycle	2/665	49/18722	0.52359369987961	0.647668682404004	DUSP1/UBE2B	2
GO:0086009	membrane repolarization	2/665	49/18722	0.52359369987961	0.647668682404004	FLNA/KCNE1	2
GO:1904752	regulation of vascular associated smooth muscle cell migration	2/665	49/18722	0.52359369987961	0.647668682404004	DOCK4/RHOA	2
GO:0031503	protein-containing complex localization	8/665	220/18722	0.523608202394223	0.647668682404004	SSB/RAB8A/RAP1A/KIF5B/STX3/TYROBP/SMAD7/SETD2	8
GO:0046883	regulation of hormone secretion	9/665	249/18722	0.526464030795129	0.651039122431399	HLA-DRB1/ALOX5/GLUL/DYNLL1/IRS2/RAC1/ANXA1/EGFR/KIF5B	9
GO:0006650	glycerophospholipid metabolic process	11/665	306/18722	0.527132533714487	0.651590698886963	CAPN2/APOC1/PLSCR1/PIP4K2A/PTEN/SOCS3/GPCPD1/SERINC1/AGPAT2/PIK3CB/ABHD5	11
GO:0043297	apical junction assembly	3/665	78/18722	0.527221079906485	0.651590698886963	RHOA/RHOC/RAB13	3
GO:0021761	limbic system development	4/665	107/18722	0.530061275427325	0.651590698886963	PTEN/UBA6/KIF5B/NRP1	4
GO:0032526	response to retinoic acid	4/665	107/18722	0.530061275427325	0.651590698886963	CTSH/DUSP1/KLF4/PTK2B	4
GO:0000002	mitochondrial genome maintenance	1/665	21/18722	0.532285359654139	0.651590698886963	TYMP	1
GO:0006067	ethanol metabolic process	1/665	21/18722	0.532285359654139	0.651590698886963	ALDH2	1
GO:0006450	regulation of translational fidelity	1/665	21/18722	0.532285359654139	0.651590698886963	GATC	1
GO:0007063	regulation of sister chromatid cohesion	1/665	21/18722	0.532285359654139	0.651590698886963	RB1	1
GO:0007252	I-kappaB phosphorylation	1/665	21/18722	0.532285359654139	0.651590698886963	TLR2	1
GO:0007350	blastoderm segmentation	1/665	21/18722	0.532285359654139	0.651590698886963	NRP1	1
GO:0010766	negative regulation of sodium ion transport	1/665	21/18722	0.532285359654139	0.651590698886963	WNK1	1
GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	1/665	21/18722	0.532285359654139	0.651590698886963	STX3	1
GO:0031998	regulation of fatty acid beta-oxidation	1/665	21/18722	0.532285359654139	0.651590698886963	IRS2	1
GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	1/665	21/18722	0.532285359654139	0.651590698886963	GMFG	1
GO:0035020	regulation of Rac protein signal transduction	1/665	21/18722	0.532285359654139	0.651590698886963	PIK3CB	1
GO:0042454	ribonucleoside catabolic process	1/665	21/18722	0.532285359654139	0.651590698886963	UPP1	1
GO:0043576	regulation of respiratory gaseous exchange	1/665	21/18722	0.532285359654139	0.651590698886963	NR4A2	1
GO:0044241	lipid digestion	1/665	21/18722	0.532285359654139	0.651590698886963	CD36	1
GO:0045056	transcytosis	1/665	21/18722	0.532285359654139	0.651590698886963	PTAFR	1
GO:0046514	ceramide catabolic process	1/665	21/18722	0.532285359654139	0.651590698886963	HEXB	1
GO:0048485	sympathetic nervous system development	1/665	21/18722	0.532285359654139	0.651590698886963	NRP1	1
GO:0048745	smooth muscle tissue development	1/665	21/18722	0.532285359654139	0.651590698886963	TIPARP	1
GO:0050849	negative regulation of calcium-mediated signaling	1/665	21/18722	0.532285359654139	0.651590698886963	PRNP	1
GO:0051152	positive regulation of smooth muscle cell differentiation	1/665	21/18722	0.532285359654139	0.651590698886963	SOD2	1
GO:0060445	branching involved in salivary gland morphogenesis	1/665	21/18722	0.532285359654139	0.651590698886963	NRP1	1
GO:0060972	left/right pattern formation	1/665	21/18722	0.532285359654139	0.651590698886963	CITED2	1
GO:0070269	pyroptosis	1/665	21/18722	0.532285359654139	0.651590698886963	TREM2	1
GO:0070584	mitochondrion morphogenesis	1/665	21/18722	0.532285359654139	0.651590698886963	PLEC	1
GO:0072170	metanephric tubule development	1/665	21/18722	0.532285359654139	0.651590698886963	STAT1	1
GO:0072243	metanephric nephron epithelium development	1/665	21/18722	0.532285359654139	0.651590698886963	STAT1	1
GO:0090026	positive regulation of monocyte chemotaxis	1/665	21/18722	0.532285359654139	0.651590698886963	CXCL12	1
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	1/665	21/18722	0.532285359654139	0.651590698886963	VEGFA	1
GO:0097734	extracellular exosome biogenesis	1/665	21/18722	0.532285359654139	0.651590698886963	SDCBP	1
GO:0098856	intestinal lipid absorption	1/665	21/18722	0.532285359654139	0.651590698886963	CD36	1
GO:0099500	vesicle fusion to plasma membrane	1/665	21/18722	0.532285359654139	0.651590698886963	STX3	1
GO:0099515	actin filament-based transport	1/665	21/18722	0.532285359654139	0.651590698886963	MYO1G	1
GO:0150105	protein localization to cell-cell junction	1/665	21/18722	0.532285359654139	0.651590698886963	FLNA	1
GO:1901863	positive regulation of muscle tissue development	1/665	21/18722	0.532285359654139	0.651590698886963	IGF2	1
GO:1902259	regulation of delayed rectifier potassium channel activity	1/665	21/18722	0.532285359654139	0.651590698886963	KCNE1	1
GO:1902473	regulation of protein localization to synapse	1/665	21/18722	0.532285359654139	0.651590698886963	RAP1A	1
GO:2000047	regulation of cell-cell adhesion mediated by cadherin	1/665	21/18722	0.532285359654139	0.651590698886963	VEGFA	1
GO:0002448	mast cell mediated immunity	2/665	50/18722	0.534504338895245	0.65221865070203	CD300A/HMOX1	2
GO:0007080	mitotic metaphase plate congression	2/665	50/18722	0.534504338895245	0.65221865070203	CHMP5/RMDN1	2
GO:0018023	peptidyl-lysine trimethylation	2/665	50/18722	0.534504338895245	0.65221865070203	LMNA/SETD2	2
GO:0038202	TORC1 signaling	2/665	50/18722	0.534504338895245	0.65221865070203	LAMTOR5/RRAGD	2
GO:0042572	retinol metabolic process	2/665	50/18722	0.534504338895245	0.65221865070203	DHRS3/CYP1B1	2
GO:0043628	ncRNA 3'-end processing	2/665	50/18722	0.534504338895245	0.65221865070203	SSB/LARP7	2
GO:0045058	T cell selection	2/665	50/18722	0.534504338895245	0.65221865070203	CD74/RHOA	2
GO:0045814	negative regulation of gene expression, epigenetic	2/665	50/18722	0.534504338895245	0.65221865070203	SPI1/ZNFX1	2
GO:0046460	neutral lipid biosynthetic process	2/665	50/18722	0.534504338895245	0.65221865070203	ACSL1/ANG	2
GO:0046463	acylglycerol biosynthetic process	2/665	50/18722	0.534504338895245	0.65221865070203	ACSL1/ANG	2
GO:0060688	regulation of morphogenesis of a branching structure	2/665	50/18722	0.534504338895245	0.65221865070203	VEGFA/LRRK2	2
GO:1901570	fatty acid derivative biosynthetic process	2/665	50/18722	0.534504338895245	0.65221865070203	ALOX5/ACSL1	2
GO:1904738	vascular associated smooth muscle cell migration	2/665	50/18722	0.534504338895245	0.65221865070203	DOCK4/RHOA	2
GO:0006446	regulation of translational initiation	3/665	79/18722	0.535855340197414	0.653706686495127	EIF2AK2/PPP1R15A/EIF4EBP1	3
GO:0055123	digestive system development	5/665	137/18722	0.539106142188318	0.657349736672213	CXCL8/EGFR/CDKN1A/IGF2/RB1	5
GO:0090090	negative regulation of canonical Wnt signaling pathway	5/665	137/18722	0.539106142188318	0.657349736672213	APOE/DAB2/EGR1/RBX1/TLE3	5
GO:0021766	hippocampus development	3/665	80/18722	0.544399306846924	0.663478311679551	PTEN/UBA6/KIF5B	3
GO:0051303	establishment of chromosome localization	3/665	80/18722	0.544399306846924	0.663478311679551	UBE2B/CHMP5/RMDN1	3
GO:0048013	ephrin receptor signaling pathway	2/665	51/18722	0.545242325820586	0.663775669792026	EPHB2/SIPA1L1	2
GO:0050982	detection of mechanical stimulus	2/665	51/18722	0.545242325820586	0.663775669792026	CXCR4/CXCL12	2
GO:0065002	intracellular protein transmembrane transport	2/665	51/18722	0.545242325820586	0.663775669792026	SEC61G/DNAJC15	2
GO:0002029	desensitization of G protein-coupled receptor signaling pathway	1/665	22/18722	0.548917103188174	0.663775669792026	ADM	1
GO:0002089	lens morphogenesis in camera-type eye	1/665	22/18722	0.548917103188174	0.663775669792026	CITED2	1
GO:0006662	glycerol ether metabolic process	1/665	22/18722	0.548917103188174	0.663775669792026	TXN	1
GO:0006907	pinocytosis	1/665	22/18722	0.548917103188174	0.663775669792026	PYCARD	1
GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	1/665	22/18722	0.548917103188174	0.663775669792026	CD9	1
GO:0007398	ectoderm development	1/665	22/18722	0.548917103188174	0.663775669792026	ITGAM	1
GO:0008211	glucocorticoid metabolic process	1/665	22/18722	0.548917103188174	0.663775669792026	YWHAH	1
GO:0021854	hypothalamus development	1/665	22/18722	0.548917103188174	0.663775669792026	NRP1	1
GO:0022401	negative adaptation of signaling pathway	1/665	22/18722	0.548917103188174	0.663775669792026	ADM	1
GO:0031061	negative regulation of histone methylation	1/665	22/18722	0.548917103188174	0.663775669792026	JARID2	1
GO:0034629	cellular protein-containing complex localization	1/665	22/18722	0.548917103188174	0.663775669792026	SMAD7	1
GO:0035357	peroxisome proliferator activated receptor signaling pathway	1/665	22/18722	0.548917103188174	0.663775669792026	CITED2	1
GO:0035584	calcium-mediated signaling using intracellular calcium source	1/665	22/18722	0.548917103188174	0.663775669792026	PRNP	1
GO:0035809	regulation of urine volume	1/665	22/18722	0.548917103188174	0.663775669792026	ADM	1
GO:0036120	cellular response to platelet-derived growth factor stimulus	1/665	22/18722	0.548917103188174	0.663775669792026	ERRFI1	1
GO:0043486	histone exchange	1/665	22/18722	0.548917103188174	0.663775669792026	ANP32E	1
GO:0044346	fibroblast apoptotic process	1/665	22/18722	0.548917103188174	0.663775669792026	BTG1	1
GO:0045048	protein insertion into ER membrane	1/665	22/18722	0.548917103188174	0.663775669792026	CAMLG	1
GO:0045061	thymic T cell selection	1/665	22/18722	0.548917103188174	0.663775669792026	CD74	1
GO:0045540	regulation of cholesterol biosynthetic process	1/665	22/18722	0.548917103188174	0.663775669792026	APOE	1
GO:0045663	positive regulation of myoblast differentiation	1/665	22/18722	0.548917103188174	0.663775669792026	BTG1	1
GO:0046628	positive regulation of insulin receptor signaling pathway	1/665	22/18722	0.548917103188174	0.663775669792026	IGF2	1
GO:0048026	positive regulation of mRNA splicing, via spliceosome	1/665	22/18722	0.548917103188174	0.663775669792026	NCL	1
GO:0060343	trabecula formation	1/665	22/18722	0.548917103188174	0.663775669792026	FBN2	1
GO:0099563	modification of synaptic structure	1/665	22/18722	0.548917103188174	0.663775669792026	RHOA	1
GO:0106118	regulation of sterol biosynthetic process	1/665	22/18722	0.548917103188174	0.663775669792026	APOE	1
GO:0140467	integrated stress response signaling	1/665	22/18722	0.548917103188174	0.663775669792026	PPP1R15A	1
GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	1/665	22/18722	0.548917103188174	0.663775669792026	VEGFA	1
GO:2000193	positive regulation of fatty acid transport	1/665	22/18722	0.548917103188174	0.663775669792026	ACSL1	1
GO:0009063	cellular amino acid catabolic process	4/665	110/18722	0.551991214885214	0.667330658715523	IL4I1/GLUL/DDAH2/KMO	4
GO:0001523	retinoid metabolic process	3/665	81/18722	0.552851163303295	0.668045290935418	DHRS3/RBP1/CYP1B1	3
GO:0014032	neural crest cell development	3/665	81/18722	0.552851163303295	0.668045290935418	CITED2/FN1/NRP1	3
GO:0043090	amino acid import	2/665	52/18722	0.555806144679917	0.671452731905491	SLC1A3/RGS2	2
GO:0015748	organophosphate ester transport	5/665	140/18722	0.558454806520387	0.674488551253056	APOE/APOC1/PLSCR1/SLC25A19/SCARB2	5
GO:0007411	axon guidance	8/665	227/18722	0.559346699666101	0.675401627147843	ALCAM/VEGFA/DPYSL2/RAC1/KIF5B/EPHB2/CXCL12/NRP1	8
GO:0097485	neuron projection guidance	8/665	228/18722	0.564359767272942	0.677241361189751	ALCAM/VEGFA/DPYSL2/RAC1/KIF5B/EPHB2/CXCL12/NRP1	8
GO:0002052	positive regulation of neuroblast proliferation	1/665	23/18722	0.564958286417044	0.677241361189751	VEGFA	1
GO:0002363	alpha-beta T cell lineage commitment	1/665	23/18722	0.564958286417044	0.677241361189751	RHOA	1
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	1/665	23/18722	0.564958286417044	0.677241361189751	RHOA	1
GO:0006541	glutamine metabolic process	1/665	23/18722	0.564958286417044	0.677241361189751	GLUL	1
GO:0006622	protein targeting to lysosome	1/665	23/18722	0.564958286417044	0.677241361189751	SCARB2	1
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	1/665	23/18722	0.564958286417044	0.677241361189751	PTPN12	1
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	1/665	23/18722	0.564958286417044	0.677241361189751	CARD16	1
GO:0021544	subpallium development	1/665	23/18722	0.564958286417044	0.677241361189751	LRRK2	1
GO:0021884	forebrain neuron development	1/665	23/18722	0.564958286417044	0.677241361189751	NRP1	1
GO:0023058	adaptation of signaling pathway	1/665	23/18722	0.564958286417044	0.677241361189751	ADM	1
GO:0030194	positive regulation of blood coagulation	1/665	23/18722	0.564958286417044	0.677241361189751	CD36	1
GO:0035162	embryonic hemopoiesis	1/665	23/18722	0.564958286417044	0.677241361189751	VEGFA	1
GO:0036119	response to platelet-derived growth factor	1/665	23/18722	0.564958286417044	0.677241361189751	ERRFI1	1
GO:0040019	positive regulation of embryonic development	1/665	23/18722	0.564958286417044	0.677241361189751	CFL1	1
GO:0042026	protein refolding	1/665	23/18722	0.564958286417044	0.677241361189751	B2M	1
GO:0045943	positive regulation of transcription by RNA polymerase I	1/665	23/18722	0.564958286417044	0.677241361189751	NCL	1
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	1/665	23/18722	0.564958286417044	0.677241361189751	CHST15	1
GO:0051446	positive regulation of meiotic cell cycle	1/665	23/18722	0.564958286417044	0.677241361189751	UBE2B	1
GO:0051590	positive regulation of neurotransmitter transport	1/665	23/18722	0.564958286417044	0.677241361189751	KMO	1
GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	1/665	23/18722	0.564958286417044	0.677241361189751	KCNE1	1
GO:0060353	regulation of cell adhesion molecule production	1/665	23/18722	0.564958286417044	0.677241361189751	CXCL8	1
GO:0060487	lung epithelial cell differentiation	1/665	23/18722	0.564958286417044	0.677241361189751	KLF2	1
GO:0060575	intestinal epithelial cell differentiation	1/665	23/18722	0.564958286417044	0.677241361189751	CDKN1A	1
GO:0071218	cellular response to misfolded protein	1/665	23/18722	0.564958286417044	0.677241361189751	RNF5	1
GO:0090208	positive regulation of triglyceride metabolic process	1/665	23/18722	0.564958286417044	0.677241361189751	ABHD5	1
GO:0140112	extracellular vesicle biogenesis	1/665	23/18722	0.564958286417044	0.677241361189751	SDCBP	1
GO:1900048	positive regulation of hemostasis	1/665	23/18722	0.564958286417044	0.677241361189751	CD36	1
GO:1904666	regulation of ubiquitin protein ligase activity	1/665	23/18722	0.564958286417044	0.677241361189751	PTEN	1
GO:2000737	negative regulation of stem cell differentiation	1/665	23/18722	0.564958286417044	0.677241361189751	ZFP36L2	1
GO:0033059	cellular pigmentation	2/665	53/18722	0.566194604390262	0.678396138818612	BLOC1S1/BLOC1S2	2
GO:0071715	icosanoid transport	2/665	53/18722	0.566194604390262	0.678396138818612	ANXA1/ABCC3	2
GO:0072522	purine-containing compound biosynthetic process	7/665	200/18722	0.569452172686102	0.682134803145319	TREM2/ALDOA/ACSL1/PAPSS1/ENO1/PAPSS2/GUK1	7
GO:0016197	endosomal transport	8/665	230/18722	0.574310494435061	0.687788712612591	RAB8A/BLOC1S1/BLOC1S2/LRRK2/RAB13/SQSTM1/VTA1/CHMP5	8
GO:0006473	protein acetylation	7/665	201/18722	0.574754446188281	0.688154564576188	NUPR1/TERF2IP/BLOC1S1/SPI1/CAMK1/MORF4L1/PER1	7
GO:1901136	carbohydrate derivative catabolic process	6/665	172/18722	0.575690960851291	0.689109844756965	TYMP/UPP1/CD44/IDS/LYVE1/HEXB	6
GO:0010524	positive regulation of calcium ion transport into cytosol	2/665	54/18722	0.576406817658098	0.689136849593637	CALM1/CALM3	2
GO:0030834	regulation of actin filament depolymerization	2/665	54/18722	0.576406817658098	0.689136849593637	CAPG/GSN	2
GO:0032330	regulation of chondrocyte differentiation	2/665	54/18722	0.576406817658098	0.689136849593637	ACVRL1/SMAD7	2
GO:0086002	cardiac muscle cell action potential involved in contraction	2/665	54/18722	0.576406817658098	0.689136849593637	FLNA/KCNE1	2
GO:2000179	positive regulation of neural precursor cell proliferation	2/665	54/18722	0.576406817658098	0.689136849593637	VEGFA/FLNA	2
GO:0030010	establishment of cell polarity	5/665	143/18722	0.57739151052141	0.689613569278333	GSN/MSN/RHOA/PTK2B/DOCK8	5
GO:0002088	lens development in camera-type eye	3/665	84/18722	0.577638086298934	0.689613569278333	VIM/SKIL/CITED2	3
GO:0006405	RNA export from nucleus	3/665	84/18722	0.577638086298934	0.689613569278333	SSB/HNRNPA1/SETD2	3
GO:0009953	dorsal/ventral pattern formation	3/665	84/18722	0.577638086298934	0.689613569278333	AIDA/ACVRL1/FBXL15	3
GO:0042440	pigment metabolic process	3/665	84/18722	0.577638086298934	0.689613569278333	TSPO/HMOX1/UROD	3
GO:0061157	mRNA destabilization	3/665	84/18722	0.577638086298934	0.689613569278333	ZFP36L2/ZFP36/TOB1	3
GO:0009913	epidermal cell differentiation	7/665	202/18722	0.580025695269491	0.689798265682241	TXNIP/KLF4/ERRFI1/ST14/ZFP36/ANXA1/PLEC	7
GO:0002244	hematopoietic progenitor cell differentiation	4/665	114/18722	0.580365921846195	0.689798265682241	EIF2AK2/CITED2/SPI1/SOS2	4
GO:0002021	response to dietary excess	1/665	24/18722	0.580429848507673	0.689798265682241	APOE	1
GO:0003148	outflow tract septum morphogenesis	1/665	24/18722	0.580429848507673	0.689798265682241	NRP1	1
GO:0006817	phosphate ion transport	1/665	24/18722	0.580429848507673	0.689798265682241	CEBPB	1
GO:0010226	response to lithium ion	1/665	24/18722	0.580429848507673	0.689798265682241	PTK2B	1
GO:0030878	thyroid gland development	1/665	24/18722	0.580429848507673	0.689798265682241	CGA	1
GO:0032528	microvillus organization	1/665	24/18722	0.580429848507673	0.689798265682241	FXYD5	1
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	1/665	24/18722	0.580429848507673	0.689798265682241	SULF2	1
GO:0050687	negative regulation of defense response to virus	1/665	24/18722	0.580429848507673	0.689798265682241	FGL2	1
GO:0050820	positive regulation of coagulation	1/665	24/18722	0.580429848507673	0.689798265682241	CD36	1
GO:0051123	RNA polymerase II preinitiation complex assembly	1/665	24/18722	0.580429848507673	0.689798265682241	PSMC6	1
GO:0060479	lung cell differentiation	1/665	24/18722	0.580429848507673	0.689798265682241	KLF2	1
GO:0060561	apoptotic process involved in morphogenesis	1/665	24/18722	0.580429848507673	0.689798265682241	SPI1	1
GO:0070841	inclusion body assembly	1/665	24/18722	0.580429848507673	0.689798265682241	PSMC6	1
GO:1901984	negative regulation of protein acetylation	1/665	24/18722	0.580429848507673	0.689798265682241	SPI1	1
GO:1903861	positive regulation of dendrite extension	1/665	24/18722	0.580429848507673	0.689798265682241	CXCR4	1
GO:2000209	regulation of anoikis	1/665	24/18722	0.580429848507673	0.689798265682241	MCL1	1
GO:2001026	regulation of endothelial cell chemotaxis	1/665	24/18722	0.580429848507673	0.689798265682241	VEGFA	1
GO:0007612	learning	5/665	144/18722	0.583607629051285	0.693243287854897	JUN/FOS/UBA6/EPHB2/TLR2	5
GO:0031644	regulation of nervous system process	5/665	144/18722	0.583607629051285	0.693243287854897	TYMP/PTEN/PTAFR/LRRK2/PTK2B	5
GO:0006643	membrane lipid metabolic process	7/665	203/18722	0.585265292924506	0.695046237953356	ST8SIA4/SERINC1/HACD4/HEXB/CYP1B1/B3GNT5/PSAP	7
GO:0072384	organelle transport along microtubule	3/665	85/18722	0.585706210382579	0.695280925424394	BLOC1S1/BLOC1S2/KIF5B	3
GO:0001755	neural crest cell migration	2/665	55/18722	0.586442180961582	0.695280925424394	FN1/NRP1	2
GO:0003229	ventricular cardiac muscle tissue development	2/665	55/18722	0.586442180961582	0.695280925424394	LY6E/SMAD7	2
GO:0006360	transcription by RNA polymerase I	2/665	55/18722	0.586442180961582	0.695280925424394	FLNA/NCL	2
GO:0031113	regulation of microtubule polymerization	2/665	55/18722	0.586442180961582	0.695280925424394	MAPRE1/RAC1	2
GO:0042220	response to cocaine	2/665	55/18722	0.586442180961582	0.695280925424394	SLC1A3/PTK2B	2
GO:0048016	inositol phosphate-mediated signaling	2/665	55/18722	0.586442180961582	0.695280925424394	CLEC7A/PRNP	2
GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	8/665	233/18722	0.589039723934343	0.698193996650056	RGS1/ADM/GNAQ/FLNA/ADGRE5/RGS2/ARRDC3/PSAP	8
GO:0043588	skin development	9/665	263/18722	0.592696546055471	0.698512600749669	TXNIP/ERRFI1/ST14/ZFP36/ANXA1/PTGES3/ARRDC3/EGFR/PLEC	9
GO:0006493	protein O-linked glycosylation	3/665	86/18722	0.593675255690364	0.698512600749669	B3GNT7/GCNT1/B3GNT5	3
GO:0014031	mesenchymal cell development	3/665	86/18722	0.593675255690364	0.698512600749669	CITED2/FN1/NRP1	3
GO:0035023	regulation of Rho protein signal transduction	3/665	86/18722	0.593675255690364	0.698512600749669	APOE/RAC1/NRP1	3
GO:1903510	mucopolysaccharide metabolic process	3/665	86/18722	0.593675255690364	0.698512600749669	CD44/B3GNT7/CHST15	3
GO:2001251	negative regulation of chromosome organization	3/665	86/18722	0.593675255690364	0.698512600749669	DUSP1/TERF2IP/HNRNPA1	3
GO:0060560	developmental growth involved in morphogenesis	8/665	234/18722	0.593894858854325	0.698512600749669	CXCR4/ALCAM/VEGFA/APOE/DPYSL2/FN1/CXCL12/NRP1	8
GO:0001964	startle response	1/665	25/18722	0.595351987278792	0.698512600749669	PTEN	1
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	1/665	25/18722	0.595351987278792	0.698512600749669	RHOA	1
GO:0003094	glomerular filtration	1/665	25/18722	0.595351987278792	0.698512600749669	SULF2	1
GO:0007288	sperm axoneme assembly	1/665	25/18722	0.595351987278792	0.698512600749669	UBE2B	1
GO:0010560	positive regulation of glycoprotein biosynthetic process	1/665	25/18722	0.595351987278792	0.698512600749669	SOAT1	1
GO:0016540	protein autoprocessing	1/665	25/18722	0.595351987278792	0.698512600749669	CAPN2	1
GO:0032469	endoplasmic reticulum calcium ion homeostasis	1/665	25/18722	0.595351987278792	0.698512600749669	GRINA	1
GO:0033233	regulation of protein sumoylation	1/665	25/18722	0.595351987278792	0.698512600749669	EGR1	1
GO:0035336	long-chain fatty-acyl-CoA metabolic process	1/665	25/18722	0.595351987278792	0.698512600749669	ACSL1	1
GO:0036315	cellular response to sterol	1/665	25/18722	0.595351987278792	0.698512600749669	INSIG2	1
GO:0046339	diacylglycerol metabolic process	1/665	25/18722	0.595351987278792	0.698512600749669	ANG	1
GO:0046949	fatty-acyl-CoA biosynthetic process	1/665	25/18722	0.595351987278792	0.698512600749669	ACSL1	1
GO:0048596	embryonic camera-type eye morphogenesis	1/665	25/18722	0.595351987278792	0.698512600749669	CITED2	1
GO:0050995	negative regulation of lipid catabolic process	1/665	25/18722	0.595351987278792	0.698512600749669	APOC1	1
GO:0051450	myoblast proliferation	1/665	25/18722	0.595351987278792	0.698512600749669	GPX1	1
GO:0051788	response to misfolded protein	1/665	25/18722	0.595351987278792	0.698512600749669	RNF5	1
GO:0060074	synapse maturation	1/665	25/18722	0.595351987278792	0.698512600749669	PTEN	1
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	1/665	25/18722	0.595351987278792	0.698512600749669	PSMC6	1
GO:0061436	establishment of skin barrier	1/665	25/18722	0.595351987278792	0.698512600749669	PLEC	1
GO:0071459	protein localization to chromosome, centromeric region	1/665	25/18722	0.595351987278792	0.698512600749669	RB1	1
GO:0072012	glomerulus vasculature development	1/665	25/18722	0.595351987278792	0.698512600749669	EGR1	1
GO:0072202	cell differentiation involved in metanephros development	1/665	25/18722	0.595351987278792	0.698512600749669	STAT1	1
GO:0072207	metanephric epithelium development	1/665	25/18722	0.595351987278792	0.698512600749669	STAT1	1
GO:0090169	regulation of spindle assembly	1/665	25/18722	0.595351987278792	0.698512600749669	CHMP5	1
GO:0098703	calcium ion import across plasma membrane	1/665	25/18722	0.595351987278792	0.698512600749669	PRNP	1
GO:0099560	synaptic membrane adhesion	1/665	25/18722	0.595351987278792	0.698512600749669	IL1RAP	1
GO:0120316	sperm flagellum assembly	1/665	25/18722	0.595351987278792	0.698512600749669	UBE2B	1
GO:1900078	positive regulation of cellular response to insulin stimulus	1/665	25/18722	0.595351987278792	0.698512600749669	IGF2	1
GO:1901798	positive regulation of signal transduction by p53 class mediator	1/665	25/18722	0.595351987278792	0.698512600749669	ZNF385A	1
GO:1902932	positive regulation of alcohol biosynthetic process	1/665	25/18722	0.595351987278792	0.698512600749669	PTAFR	1
GO:1903792	negative regulation of anion transport	1/665	25/18722	0.595351987278792	0.698512600749669	RGS2	1
GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA	1/665	25/18722	0.595351987278792	0.698512600749669	EGFR	1
GO:1904753	negative regulation of vascular associated smooth muscle cell migration	1/665	25/18722	0.595351987278792	0.698512600749669	RHOA	1
GO:1904754	positive regulation of vascular associated smooth muscle cell migration	1/665	25/18722	0.595351987278792	0.698512600749669	DOCK4	1
GO:1905048	regulation of metallopeptidase activity	1/665	25/18722	0.595351987278792	0.698512600749669	TIMP1	1
GO:1905564	positive regulation of vascular endothelial cell proliferation	1/665	25/18722	0.595351987278792	0.698512600749669	IGF2	1
GO:0043010	camera-type eye development	11/665	322/18722	0.595545549633034	0.698574789161241	VIM/VEGFA/KLF4/MERTK/SKIL/CITED2/FBN2/ACVRL1/EPHB2/CYP1B1/NRP1	11
GO:0007043	cell-cell junction assembly	5/665	146/18722	0.595890425777204	0.698635730120881	CD9/RHOA/RHOC/RAB13/SMAD7	5
GO:0006687	glycosphingolipid metabolic process	2/665	56/18722	0.596300355567963	0.698635730120881	ST8SIA4/HEXB	2
GO:0015800	acidic amino acid transport	2/665	56/18722	0.596300355567963	0.698635730120881	SLC1A3/KMO	2
GO:0045599	negative regulation of fat cell differentiation	2/665	56/18722	0.596300355567963	0.698635730120881	ZFP36L2/CCDC85B	2
GO:0070534	protein K63-linked ubiquitination	2/665	56/18722	0.596300355567963	0.698635730120881	UBE2B/RNF5	2
GO:0051225	spindle assembly	4/665	117/18722	0.600956635162954	0.703925165392383	MAPRE1/FLNA/RHOA/CHMP5	4
GO:0007029	endoplasmic reticulum organization	3/665	87/18722	0.601544218572717	0.704265265125439	LRRK2/RTN3/CAMLG	3
GO:0061014	positive regulation of mRNA catabolic process	3/665	87/18722	0.601544218572717	0.704265265125439	ZFP36L2/ZFP36/TOB1	3
GO:0016331	morphogenesis of embryonic epithelium	5/665	147/18722	0.601955502264158	0.704265265125439	ADM/ST14/CITED2/RALA/SETD2	5
GO:1902652	secondary alcohol metabolic process	5/665	147/18722	0.601955502264158	0.704265265125439	APOE/IDH1/OSBPL1A/SOAT1/INSIG2	5
GO:1902850	microtubule cytoskeleton organization involved in mitosis	5/665	147/18722	0.601955502264158	0.704265265125439	FLNA/RHOA/CHMP5/RMDN1/SETD2	5
GO:0051480	regulation of cytosolic calcium ion concentration	12/665	353/18722	0.603006423205912	0.705328765199666	CXCR4/FPR3/CALM1/ERO1A/ADM/C5AR1/CD36/CLIC2/CALM3/PTK2B/DIAPH1/PRNP	12
GO:0006695	cholesterol biosynthetic process	2/665	57/18722	0.605981249538104	0.707382960197902	APOE/INSIG2	2
GO:0016447	somatic recombination of immunoglobulin gene segments	2/665	57/18722	0.605981249538104	0.707382960197902	IL27RA/TFRC	2
GO:0051155	positive regulation of striated muscle cell differentiation	2/665	57/18722	0.605981249538104	0.707382960197902	HAMP/MMP14	2
GO:0061005	cell differentiation involved in kidney development	2/665	57/18722	0.605981249538104	0.707382960197902	STAT1/PRKX	2
GO:1902653	secondary alcohol biosynthetic process	2/665	57/18722	0.605981249538104	0.707382960197902	APOE/INSIG2	2
GO:0006413	translational initiation	4/665	118/18722	0.607683464042514	0.707382960197902	EIF2AK2/PPP1R15A/EIF4EBP1/EIF4E	4
GO:1903313	positive regulation of mRNA metabolic process	4/665	118/18722	0.607683464042514	0.707382960197902	ZFP36L2/ZFP36/NCL/TOB1	4
GO:0050779	RNA destabilization	3/665	88/18722	0.60931221470899	0.707382960197902	ZFP36L2/ZFP36/TOB1	3
GO:0002026	regulation of the force of heart contraction	1/665	26/18722	0.609744185410022	0.707382960197902	ADM	1
GO:0002092	positive regulation of receptor internalization	1/665	26/18722	0.609744185410022	0.707382960197902	VEGFA	1
GO:0003416	endochondral bone growth	1/665	26/18722	0.609744185410022	0.707382960197902	ECM1	1
GO:0006517	protein deglycosylation	1/665	26/18722	0.609744185410022	0.707382960197902	RNF5	1
GO:0007214	gamma-aminobutyric acid signaling pathway	1/665	26/18722	0.609744185410022	0.707382960197902	GABRB2	1
GO:0009164	nucleoside catabolic process	1/665	26/18722	0.609744185410022	0.707382960197902	UPP1	1
GO:0018027	peptidyl-lysine dimethylation	1/665	26/18722	0.609744185410022	0.707382960197902	SETD2	1
GO:0042537	benzene-containing compound metabolic process	1/665	26/18722	0.609744185410022	0.707382960197902	KMO	1
GO:0042634	regulation of hair cycle	1/665	26/18722	0.609744185410022	0.707382960197902	PER1	1
GO:0043094	cellular metabolic compound salvage	1/665	26/18722	0.609744185410022	0.707382960197902	UPP1	1
GO:0045026	plasma membrane fusion	1/665	26/18722	0.609744185410022	0.707382960197902	CD9	1
GO:0045745	positive regulation of G protein-coupled receptor signaling pathway	1/665	26/18722	0.609744185410022	0.707382960197902	PHB	1
GO:0048843	negative regulation of axon extension involved in axon guidance	1/665	26/18722	0.609744185410022	0.707382960197902	NRP1	1
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	1/665	26/18722	0.609744185410022	0.707382960197902	CD81	1
GO:0051560	mitochondrial calcium ion homeostasis	1/665	26/18722	0.609744185410022	0.707382960197902	BNIP3	1
GO:0060544	regulation of necroptotic process	1/665	26/18722	0.609744185410022	0.707382960197902	YBX3	1
GO:0070102	interleukin-6-mediated signaling pathway	1/665	26/18722	0.609744185410022	0.707382960197902	SPI1	1
GO:0070193	synaptonemal complex organization	1/665	26/18722	0.609744185410022	0.707382960197902	UBE2B	1
GO:0070920	regulation of production of small RNA involved in gene silencing by RNA	1/665	26/18722	0.609744185410022	0.707382960197902	EGFR	1
GO:0071425	hematopoietic stem cell proliferation	1/665	26/18722	0.609744185410022	0.707382960197902	EIF2AK2	1
GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	1/665	26/18722	0.609744185410022	0.707382960197902	ARRDC3	1
GO:0072273	metanephric nephron morphogenesis	1/665	26/18722	0.609744185410022	0.707382960197902	STAT1	1
GO:0097186	amelogenesis	1/665	26/18722	0.609744185410022	0.707382960197902	FAM20C	1
GO:0097205	renal filtration	1/665	26/18722	0.609744185410022	0.707382960197902	SULF2	1
GO:1902656	calcium ion import into cytosol	1/665	26/18722	0.609744185410022	0.707382960197902	PRNP	1
GO:1905063	regulation of vascular associated smooth muscle cell differentiation	1/665	26/18722	0.609744185410022	0.707382960197902	SOD2	1
GO:2000050	regulation of non-canonical Wnt signaling pathway	1/665	26/18722	0.609744185410022	0.707382960197902	DAB2	1
GO:0007405	neuroblast proliferation	2/665	58/18722	0.61548500067208	0.712878222638136	VEGFA/LRRK2	2
GO:0010559	regulation of glycoprotein biosynthetic process	2/665	58/18722	0.61548500067208	0.712878222638136	SOAT1/TMEM59	2
GO:0043506	regulation of JUN kinase activity	2/665	58/18722	0.61548500067208	0.712878222638136	AIDA/PTK2B	2
GO:0045604	regulation of epidermal cell differentiation	2/665	58/18722	0.61548500067208	0.712878222638136	ERRFI1/ZFP36	2
GO:0050432	catecholamine secretion	2/665	58/18722	0.61548500067208	0.712878222638136	LY6E/CXCL12	2
GO:1902808	positive regulation of cell cycle G1/S phase transition	2/665	58/18722	0.61548500067208	0.712878222638136	ANXA1/EGFR	2
GO:2000736	regulation of stem cell differentiation	2/665	58/18722	0.61548500067208	0.712878222638136	ZFP36L2/EIF2AK2	2
GO:0007052	mitotic spindle organization	4/665	120/18722	0.620927118468618	0.717956317247357	FLNA/RHOA/CHMP5/RMDN1	4
GO:0001835	blastocyst hatching	1/665	27/18722	0.623625235725723	0.717956317247357	SMIM14	1
GO:0001958	endochondral ossification	1/665	27/18722	0.623625235725723	0.717956317247357	MMP14	1
GO:0002227	innate immune response in mucosa	1/665	27/18722	0.623625235725723	0.717956317247357	RPL39	1
GO:0009651	response to salt stress	1/665	27/18722	0.623625235725723	0.717956317247357	KMO	1
GO:0010561	negative regulation of glycoprotein biosynthetic process	1/665	27/18722	0.623625235725723	0.717956317247357	TMEM59	1
GO:0015813	L-glutamate transmembrane transport	1/665	27/18722	0.623625235725723	0.717956317247357	SLC1A3	1
GO:0016556	mRNA modification	1/665	27/18722	0.623625235725723	0.717956317247357	ZC3H13	1
GO:0032781	positive regulation of ATPase activity	1/665	27/18722	0.623625235725723	0.717956317247357	GABARAPL2	1
GO:0032786	positive regulation of DNA-templated transcription, elongation	1/665	27/18722	0.623625235725723	0.717956317247357	EAPP	1
GO:0032967	positive regulation of collagen biosynthetic process	1/665	27/18722	0.623625235725723	0.717956317247357	VIM	1
GO:0033561	regulation of water loss via skin	1/665	27/18722	0.623625235725723	0.717956317247357	PLEC	1
GO:0034505	tooth mineralization	1/665	27/18722	0.623625235725723	0.717956317247357	FAM20C	1
GO:0035188	hatching	1/665	27/18722	0.623625235725723	0.717956317247357	SMIM14	1
GO:0035235	ionotropic glutamate receptor signaling pathway	1/665	27/18722	0.623625235725723	0.717956317247357	PTK2B	1
GO:0036075	replacement ossification	1/665	27/18722	0.623625235725723	0.717956317247357	MMP14	1
GO:0045830	positive regulation of isotype switching	1/665	27/18722	0.623625235725723	0.717956317247357	TFRC	1
GO:0051953	negative regulation of amine transport	1/665	27/18722	0.623625235725723	0.717956317247357	RGS2	1
GO:0060512	prostate gland morphogenesis	1/665	27/18722	0.623625235725723	0.717956317247357	CRIP1	1
GO:0070861	regulation of protein exit from endoplasmic reticulum	1/665	27/18722	0.623625235725723	0.717956317247357	CD81	1
GO:0071684	organism emergence from protective structure	1/665	27/18722	0.623625235725723	0.717956317247357	SMIM14	1
GO:0099625	ventricular cardiac muscle cell membrane repolarization	1/665	27/18722	0.623625235725723	0.717956317247357	KCNE1	1
GO:1900746	regulation of vascular endothelial growth factor signaling pathway	1/665	27/18722	0.623625235725723	0.717956317247357	PIK3CB	1
GO:1901018	positive regulation of potassium ion transmembrane transporter activity	1/665	27/18722	0.623625235725723	0.717956317247357	TREM2	1
GO:1903859	regulation of dendrite extension	1/665	27/18722	0.623625235725723	0.717956317247357	CXCR4	1
GO:1904357	negative regulation of telomere maintenance via telomere lengthening	1/665	27/18722	0.623625235725723	0.717956317247357	HNRNPA1	1
GO:0048477	oogenesis	3/665	90/18722	0.624542339398582	0.718823019201123	ANG/PTK2B/HEXB	3
GO:0006767	water-soluble vitamin metabolic process	2/665	59/18722	0.624811960351882	0.718823019201123	SLC2A3/SLC25A19	2
GO:2000351	regulation of endothelial cell apoptotic process	2/665	59/18722	0.624811960351882	0.718823019201123	TNFAIP3/ANGPTL4	2
GO:0030902	hindbrain development	5/665	151/18722	0.625690291421515	0.719666917001835	FCGR2B/ATF5/C5AR1/MAFB/FLNA	5
GO:0006457	protein folding	7/665	212/18722	0.630904408296742	0.725328454599771	B2M/CD74/ERO1A/FKBP5/PTGES3/GRN/PFDN6	7
GO:0030258	lipid modification	7/665	212/18722	0.630904408296742	0.725328454599771	APOE/APOC1/ALOX5/HSD17B4/IRS2/PTEN/SOAT1	7
GO:0016125	sterol metabolic process	5/665	152/18722	0.631489442460369	0.72558470386303	APOE/OSBPL1A/SOAT1/INSIG2/CYP1B1	5
GO:0021915	neural tube development	5/665	152/18722	0.631489442460369	0.72558470386303	ADM/ST14/CITED2/RALA/SETD2	5
GO:0002065	columnar/cuboidal epithelial cell differentiation	3/665	91/18722	0.63200325614146	0.72558470386303	CEBPB/CDKN1A/FAM20C	3
GO:0014033	neural crest cell differentiation	3/665	91/18722	0.63200325614146	0.72558470386303	CITED2/FN1/NRP1	3
GO:0051952	regulation of amine transport	3/665	91/18722	0.63200325614146	0.72558470386303	RGS2/KMO/CXCL12	3
GO:0051983	regulation of chromosome segregation	3/665	91/18722	0.63200325614146	0.72558470386303	DUSP1/PLSCR1/RB1	3
GO:0006289	nucleotide-excision repair	2/665	60/18722	0.633962678239153	0.727162361146686	RPA2/XPC	2
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	2/665	60/18722	0.633962678239153	0.727162361146686	CDKN1A/FOXN3	2
GO:0030071	regulation of mitotic metaphase/anaphase transition	2/665	60/18722	0.633962678239153	0.727162361146686	DUSP1/RB1	2
GO:0055008	cardiac muscle tissue morphogenesis	2/665	60/18722	0.633962678239153	0.727162361146686	LY6E/SMAD7	2
GO:0003156	regulation of animal organ formation	1/665	28/18722	0.637013265586241	0.727805960911177	CITED2	1
GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	1/665	28/18722	0.637013265586241	0.727805960911177	RNF5	1
GO:0007064	mitotic sister chromatid cohesion	1/665	28/18722	0.637013265586241	0.727805960911177	RB1	1
GO:0007271	synaptic transmission, cholinergic	1/665	28/18722	0.637013265586241	0.727805960911177	APOE	1
GO:0008299	isoprenoid biosynthetic process	1/665	28/18722	0.637013265586241	0.727805960911177	RBP1	1
GO:0009312	oligosaccharide biosynthetic process	1/665	28/18722	0.637013265586241	0.727805960911177	FBP1	1
GO:0010460	positive regulation of heart rate	1/665	28/18722	0.637013265586241	0.727805960911177	ADM	1
GO:0010714	positive regulation of collagen metabolic process	1/665	28/18722	0.637013265586241	0.727805960911177	VIM	1
GO:0015740	C4-dicarboxylate transport	1/665	28/18722	0.637013265586241	0.727805960911177	SLC1A3	1
GO:0042983	amyloid precursor protein biosynthetic process	1/665	28/18722	0.637013265586241	0.727805960911177	SOAT1	1
GO:0042984	regulation of amyloid precursor protein biosynthetic process	1/665	28/18722	0.637013265586241	0.727805960911177	SOAT1	1
GO:0044331	cell-cell adhesion mediated by cadherin	1/665	28/18722	0.637013265586241	0.727805960911177	VEGFA	1
GO:0045671	negative regulation of osteoclast differentiation	1/665	28/18722	0.637013265586241	0.727805960911177	MAFB	1
GO:0045686	negative regulation of glial cell differentiation	1/665	28/18722	0.637013265586241	0.727805960911177	TREM2	1
GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	1/665	28/18722	0.637013265586241	0.727805960911177	SOCS3	1
GO:0060325	face morphogenesis	1/665	28/18722	0.637013265586241	0.727805960911177	TIPARP	1
GO:1903020	positive regulation of glycoprotein metabolic process	1/665	28/18722	0.637013265586241	0.727805960911177	SOAT1	1
GO:0070509	calcium ion import	3/665	92/18722	0.639360773954107	0.730320166985041	LGALS3/CXCL12/PRNP	3
GO:0043966	histone H3 acetylation	2/665	61/18722	0.64293788778777	0.734237431595867	SPI1/PER1	2
GO:1901992	positive regulation of mitotic cell cycle phase transition	3/665	93/18722	0.646614539663717	0.738266543103302	ANXA1/EGFR/RB1	3
GO:0006665	sphingolipid metabolic process	5/665	155/18722	0.648555278016997	0.738991313035353	ST8SIA4/SERINC1/HACD4/HEXB/PSAP	5
GO:0003007	heart morphogenesis	8/665	246/18722	0.649836764693949	0.738991313035353	VEGFA/LY6E/CITED2/FLNA/DHRS3/ACVRL1/SMAD7/NRP1	8
GO:0002360	T cell lineage commitment	1/665	29/18722	0.649925760418013	0.738991313035353	RHOA	1
GO:0006656	phosphatidylcholine biosynthetic process	1/665	29/18722	0.649925760418013	0.738991313035353	CAPN2	1
GO:0006688	glycosphingolipid biosynthetic process	1/665	29/18722	0.649925760418013	0.738991313035353	ST8SIA4	1
GO:0010390	histone monoubiquitination	1/665	29/18722	0.649925760418013	0.738991313035353	DTX3L	1
GO:0010592	positive regulation of lamellipodium assembly	1/665	29/18722	0.649925760418013	0.738991313035353	RAC1	1
GO:0019082	viral protein processing	1/665	29/18722	0.649925760418013	0.738991313035353	PARP9	1
GO:0019433	triglyceride catabolic process	1/665	29/18722	0.649925760418013	0.738991313035353	ABHD5	1
GO:0032372	negative regulation of sterol transport	1/665	29/18722	0.649925760418013	0.738991313035353	APOC1	1
GO:0032375	negative regulation of cholesterol transport	1/665	29/18722	0.649925760418013	0.738991313035353	APOC1	1
GO:0034067	protein localization to Golgi apparatus	1/665	29/18722	0.649925760418013	0.738991313035353	VPS13A	1
GO:0040018	positive regulation of multicellular organism growth	1/665	29/18722	0.649925760418013	0.738991313035353	IGF2	1
GO:0042759	long-chain fatty acid biosynthetic process	1/665	29/18722	0.649925760418013	0.738991313035353	ALOX5	1
GO:0060441	epithelial tube branching involved in lung morphogenesis	1/665	29/18722	0.649925760418013	0.738991313035353	CTSH	1
GO:0070198	protein localization to chromosome, telomeric region	1/665	29/18722	0.649925760418013	0.738991313035353	TERF2IP	1
GO:0098868	bone growth	1/665	29/18722	0.649925760418013	0.738991313035353	ECM1	1
GO:1902547	regulation of cellular response to vascular endothelial growth factor stimulus	1/665	29/18722	0.649925760418013	0.738991313035353	PIK3CB	1
GO:0120032	regulation of plasma membrane bounded cell projection assembly	6/665	186/18722	0.651528111237544	0.740036625060085	RAC1/RALA/ABI3/ATG3/AGRN/NRP1	6
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	2/665	62/18722	0.651738492532796	0.740036625060085	DUSP1/RB1	2
GO:0007588	excretion	2/665	62/18722	0.651738492532796	0.740036625060085	HMOX1/KCNMA1	2
GO:0032835	glomerulus development	2/665	62/18722	0.651738492532796	0.740036625060085	SULF2/EGR1	2
GO:0046148	pigment biosynthetic process	2/665	62/18722	0.651738492532796	0.740036625060085	TSPO/UROD	2
GO:0046173	polyol biosynthetic process	2/665	62/18722	0.651738492532796	0.740036625060085	PTAFR/PTK2B	2
GO:0070646	protein modification by small protein removal	5/665	157/18722	0.659651662930735	0.748850791403781	OTUD1/TNFAIP3/USP18/TANK/COPS2	5
GO:1902099	regulation of metaphase/anaphase transition of cell cycle	2/665	63/18722	0.6603655531191	0.749318903881718	DUSP1/RB1	2
GO:2000242	negative regulation of reproductive process	2/665	63/18722	0.6603655531191	0.749318903881718	DUSP1/TIMP1	2
GO:0060491	regulation of cell projection assembly	6/665	188/18722	0.661659073668414	0.749550670417124	RAC1/RALA/ABI3/ATG3/AGRN/NRP1	6
GO:0006884	cell volume homeostasis	1/665	30/18722	0.662379586412879	0.749550670417124	KCNMA1	1
GO:0015721	bile acid and bile salt transport	1/665	30/18722	0.662379586412879	0.749550670417124	ABCC3	1
GO:0030204	chondroitin sulfate metabolic process	1/665	30/18722	0.662379586412879	0.749550670417124	CHST15	1
GO:0034390	smooth muscle cell apoptotic process	1/665	30/18722	0.662379586412879	0.749550670417124	SOD2	1
GO:0034391	regulation of smooth muscle cell apoptotic process	1/665	30/18722	0.662379586412879	0.749550670417124	SOD2	1
GO:0034508	centromere complex assembly	1/665	30/18722	0.662379586412879	0.749550670417124	RB1	1
GO:0045070	positive regulation of viral genome replication	1/665	30/18722	0.662379586412879	0.749550670417124	IFIT1	1
GO:0045948	positive regulation of translational initiation	1/665	30/18722	0.662379586412879	0.749550670417124	PPP1R15A	1
GO:0060218	hematopoietic stem cell differentiation	1/665	30/18722	0.662379586412879	0.749550670417124	EIF2AK2	1
GO:1900101	regulation of endoplasmic reticulum unfolded protein response	1/665	30/18722	0.662379586412879	0.749550670417124	PPP1R15A	1
GO:1903019	negative regulation of glycoprotein metabolic process	1/665	30/18722	0.662379586412879	0.749550670417124	TMEM59	1
GO:0048565	digestive tract development	4/665	127/18722	0.665010646767646	0.752356684369497	CXCL8/EGFR/CDKN1A/RB1	4
GO:0035282	segmentation	3/665	96/18722	0.667751173558699	0.75476991871429	MAFB/ABI1/NRP1	3
GO:0042472	inner ear morphogenesis	3/665	96/18722	0.667751173558699	0.75476991871429	MAFB/INSIG2/EPHB2	3
GO:0042632	cholesterol homeostasis	3/665	96/18722	0.667751173558699	0.75476991871429	APOE/CNBP/SOAT1	3
GO:0051304	chromosome separation	3/665	96/18722	0.667751173558699	0.75476991871429	DUSP1/PLSCR1/RB1	3
GO:0016126	sterol biosynthetic process	2/665	64/18722	0.668820275034495	0.755291244472038	APOE/INSIG2	2
GO:0030858	positive regulation of epithelial cell differentiation	2/665	64/18722	0.668820275034495	0.755291244472038	BTG1/ACVRL1	2
GO:0045995	regulation of embryonic development	2/665	64/18722	0.668820275034495	0.755291244472038	PHLDA2/CFL1	2
GO:1903018	regulation of glycoprotein metabolic process	2/665	64/18722	0.668820275034495	0.755291244472038	SOAT1/TMEM59	2
GO:0032200	telomere organization	5/665	159/18722	0.670519861051881	0.756866615813729	TERF2IP/NOP10/PTGES3/RPA2/HNRNPA1	5
GO:0035966	response to topologically incorrect protein	5/665	159/18722	0.670519861051881	0.756866615813729	EIF2AK2/ERO1A/ATF3/PPP1R15A/RNF5	5
GO:0001654	eye development	12/665	371/18722	0.670675014599162	0.756869850717038	VIM/VEGFA/KLF4/MERTK/SKIL/SCO2/CITED2/FBN2/ACVRL1/EPHB2/CYP1B1/NRP1	12
GO:0002323	natural killer cell activation involved in immune response	1/665	31/18722	0.674391012425902	0.758480047919605	HLA-F	1
GO:0006301	postreplication repair	1/665	31/18722	0.674391012425902	0.758480047919605	UBE2B	1
GO:0018200	peptidyl-glutamic acid modification	1/665	31/18722	0.674391012425902	0.758480047919605	VKORC1	1
GO:0030149	sphingolipid catabolic process	1/665	31/18722	0.674391012425902	0.758480047919605	HEXB	1
GO:0030201	heparan sulfate proteoglycan metabolic process	1/665	31/18722	0.674391012425902	0.758480047919605	SULF2	1
GO:0030212	hyaluronan metabolic process	1/665	31/18722	0.674391012425902	0.758480047919605	CD44	1
GO:0034656	nucleobase-containing small molecule catabolic process	1/665	31/18722	0.674391012425902	0.758480047919605	UPP1	1
GO:0048566	embryonic digestive tract development	1/665	31/18722	0.674391012425902	0.758480047919605	CXCL8	1
GO:0048710	regulation of astrocyte differentiation	1/665	31/18722	0.674391012425902	0.758480047919605	TREM2	1
GO:0050482	arachidonic acid secretion	1/665	31/18722	0.674391012425902	0.758480047919605	ANXA1	1
GO:0055075	potassium ion homeostasis	1/665	31/18722	0.674391012425902	0.758480047919605	KCNMA1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	1/665	31/18722	0.674391012425902	0.758480047919605	KLF4	1
GO:0070633	transepithelial transport	1/665	31/18722	0.674391012425902	0.758480047919605	SLC1A3	1
GO:1900027	regulation of ruffle assembly	1/665	31/18722	0.674391012425902	0.758480047919605	ABI3	1
GO:1903963	arachidonate transport	1/665	31/18722	0.674391012425902	0.758480047919605	ANXA1	1
GO:0055092	sterol homeostasis	3/665	97/18722	0.674588213054686	0.758530185267373	APOE/CNBP/SOAT1	3
GO:0010965	regulation of mitotic sister chromatid separation	2/665	65/18722	0.677103997013852	0.76032690130114	DUSP1/RB1	2
GO:0044784	metaphase/anaphase transition of cell cycle	2/665	65/18722	0.677103997013852	0.76032690130114	DUSP1/RB1	2
GO:0045682	regulation of epidermis development	2/665	65/18722	0.677103997013852	0.76032690130114	ERRFI1/ZFP36	2
GO:0051310	metaphase plate congression	2/665	65/18722	0.677103997013852	0.76032690130114	CHMP5/RMDN1	2
GO:0072577	endothelial cell apoptotic process	2/665	65/18722	0.677103997013852	0.76032690130114	TNFAIP3/ANGPTL4	2
GO:1902475	L-alpha-amino acid transmembrane transport	2/665	65/18722	0.677103997013852	0.76032690130114	SLC1A3/RGS2	2
GO:0003205	cardiac chamber development	5/665	161/18722	0.681157482333135	0.764705824982082	LY6E/CITED2/DHRS3/SMAD7/NRP1	5
GO:0030534	adult behavior	4/665	130/18722	0.682797475413886	0.766200824747576	NR4A2/CSTB/PTEN/CXCL12	4
GO:0042476	odontogenesis	4/665	130/18722	0.682797475413886	0.766200824747576	SNX10/ADM/RHOA/FAM20C	4
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	2/665	66/18722	0.6852181800821	0.766823972912009	IL27RA/TFRC	2
GO:0006303	double-strand break repair via nonhomologous end joining	2/665	66/18722	0.6852181800821	0.766823972912009	DTX3L/PARP9	2
GO:0016444	somatic cell DNA recombination	2/665	66/18722	0.6852181800821	0.766823972912009	IL27RA/TFRC	2
GO:0071300	cellular response to retinoic acid	2/665	66/18722	0.6852181800821	0.766823972912009	KLF4/PTK2B	2
GO:0003180	aortic valve morphogenesis	1/665	32/18722	0.685975731099958	0.766823972912009	RB1	1
GO:0003338	metanephros morphogenesis	1/665	32/18722	0.685975731099958	0.766823972912009	STAT1	1
GO:0007435	salivary gland morphogenesis	1/665	32/18722	0.685975731099958	0.766823972912009	NRP1	1
GO:0008156	negative regulation of DNA replication	1/665	32/18722	0.685975731099958	0.766823972912009	S100A11	1
GO:0010667	negative regulation of cardiac muscle cell apoptotic process	1/665	32/18722	0.685975731099958	0.766823972912009	NUPR1	1
GO:0019228	neuronal action potential	1/665	32/18722	0.685975731099958	0.766823972912009	SCN9A	1
GO:0030431	sleep	1/665	32/18722	0.685975731099958	0.766823972912009	FOS	1
GO:0045761	regulation of adenylate cyclase activity	1/665	32/18722	0.685975731099958	0.766823972912009	CAP1	1
GO:0045879	negative regulation of smoothened signaling pathway	1/665	32/18722	0.685975731099958	0.766823972912009	RB1	1
GO:0046856	phosphatidylinositol dephosphorylation	1/665	32/18722	0.685975731099958	0.766823972912009	PTEN	1
GO:0050685	positive regulation of mRNA processing	1/665	32/18722	0.685975731099958	0.766823972912009	NCL	1
GO:0051642	centrosome localization	1/665	32/18722	0.685975731099958	0.766823972912009	KIF5B	1
GO:0060323	head morphogenesis	1/665	32/18722	0.685975731099958	0.766823972912009	TIPARP	1
GO:0021953	central nervous system neuron differentiation	5/665	162/18722	0.686389224409648	0.76711365984168	B2M/NR4A2/PTEN/EPHB2/NRP1	5
GO:0015837	amine transport	3/665	99/18722	0.687949868046546	0.768684991949491	RGS2/KMO/CXCL12	3
GO:0018205	peptidyl-lysine modification	12/665	376/18722	0.688261247708004	0.768860058689319	IFIH1/SUMO2/BLOC1S1/EGR1/LMNA/SPI1/MORF4L1/SUMO3/ZBED1/JARID2/PER1/SETD2	12
GO:0006661	phosphatidylinositol biosynthetic process	4/665	131/18722	0.68857707903245	0.769040018604781	PIP4K2A/PTEN/SOCS3/PIK3CB	4
GO:0043414	macromolecule methylation	10/665	316/18722	0.689478363241175	0.769873616110681	BTG1/SNRPB/FOS/LMNA/LARP7/SPI1/KDM1B/JARID2/ZC3H13/SETD2	10
GO:0016445	somatic diversification of immunoglobulins	2/665	67/18722	0.693164397205485	0.773294512707354	IL27RA/TFRC	2
GO:0048814	regulation of dendrite morphogenesis	2/665	67/18722	0.693164397205485	0.773294512707354	YWHAH/SIPA1L1	2
GO:0051306	mitotic sister chromatid separation	2/665	67/18722	0.693164397205485	0.773294512707354	DUSP1/RB1	2
GO:0061180	mammary gland epithelium development	2/665	67/18722	0.693164397205485	0.773294512707354	CEBPB/GPX1	2
GO:0035264	multicellular organism growth	4/665	132/18722	0.694281832999166	0.773887899965171	ATF5/KLF2/PLEC/IGF2	4
GO:0006664	glycolipid metabolic process	3/665	100/18722	0.694474855904359	0.773887899965171	ST8SIA4/HEXB/B3GNT5	3
GO:0006910	phagocytosis, recognition	3/665	100/18722	0.694474855904359	0.773887899965171	TREM2/CLEC7A/CD36	3
GO:0044728	DNA methylation or demethylation	3/665	100/18722	0.694474855904359	0.773887899965171	FOS/SPI1/KDM1B	3
GO:0060079	excitatory postsynaptic potential	3/665	100/18722	0.694474855904359	0.773887899965171	PTEN/LRRK2/PTK2B	3
GO:0030705	cytoskeleton-dependent intracellular transport	6/665	195/18722	0.695641385849525	0.77391778642939	MYO1G/TANC2/BLOC1S1/BLOC1S2/DST/KIF5B	6
GO:0003382	epithelial cell morphogenesis	1/665	33/18722	0.697148879244341	0.77391778642939	ST14	1
GO:0006536	glutamate metabolic process	1/665	33/18722	0.697148879244341	0.77391778642939	GLUL	1
GO:0006891	intra-Golgi vesicle-mediated transport	1/665	33/18722	0.697148879244341	0.77391778642939	GABARAPL2	1
GO:0033198	response to ATP	1/665	33/18722	0.697148879244341	0.77391778642939	PTEN	1
GO:0035025	positive regulation of Rho protein signal transduction	1/665	33/18722	0.697148879244341	0.77391778642939	RAC1	1
GO:0040020	regulation of meiotic nuclear division	1/665	33/18722	0.697148879244341	0.77391778642939	UBE2B	1
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	1/665	33/18722	0.697148879244341	0.77391778642939	PTK2B	1
GO:0046320	regulation of fatty acid oxidation	1/665	33/18722	0.697148879244341	0.77391778642939	IRS2	1
GO:0048333	mesodermal cell differentiation	1/665	33/18722	0.697148879244341	0.77391778642939	KLF4	1
GO:0048730	epidermis morphogenesis	1/665	33/18722	0.697148879244341	0.77391778642939	KLF4	1
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	1/665	33/18722	0.697148879244341	0.77391778642939	PSMC6	1
GO:0061842	microtubule organizing center localization	1/665	33/18722	0.697148879244341	0.77391778642939	KIF5B	1
GO:0071353	cellular response to interleukin-4	1/665	33/18722	0.697148879244341	0.77391778642939	NFIL3	1
GO:0099174	regulation of presynapse organization	1/665	33/18722	0.697148879244341	0.77391778642939	IL1RAP	1
GO:0120033	negative regulation of plasma membrane bounded cell projection assembly	1/665	33/18722	0.697148879244341	0.77391778642939	ABI3	1
GO:1905606	regulation of presynapse assembly	1/665	33/18722	0.697148879244341	0.77391778642939	IL1RAP	1
GO:0048024	regulation of mRNA splicing, via spliceosome	3/665	101/18722	0.700896313842321	0.777436573957441	NCL/LARP7/HNRNPA1	3
GO:1903509	liposaccharide metabolic process	3/665	101/18722	0.700896313842321	0.777436573957441	ST8SIA4/HEXB/B3GNT5	3
GO:0009247	glycolipid biosynthetic process	2/665	68/18722	0.70094432352179	0.777436573957441	ST8SIA4/B3GNT5	2
GO:0042698	ovulation cycle	2/665	68/18722	0.70094432352179	0.777436573957441	EGR1/EGFR	2
GO:1902749	regulation of cell cycle G2/M phase transition	3/665	102/18722	0.707214595349131	0.783430758348643	ATF5/CDKN1A/FOXN3	3
GO:1990542	mitochondrial transmembrane transport	3/665	102/18722	0.707214595349131	0.783430758348643	SLC25A37/DNAJC15/MRPL18	3
GO:0007431	salivary gland development	1/665	34/18722	0.707925057493714	0.783430758348643	NRP1	1
GO:0032212	positive regulation of telomere maintenance via telomerase	1/665	34/18722	0.707925057493714	0.783430758348643	HNRNPA1	1
GO:0035909	aorta morphogenesis	1/665	34/18722	0.707925057493714	0.783430758348643	ACVRL1	1
GO:0042573	retinoic acid metabolic process	1/665	34/18722	0.707925057493714	0.783430758348643	RBP1	1
GO:0043276	anoikis	1/665	34/18722	0.707925057493714	0.783430758348643	MCL1	1
GO:0048854	brain morphogenesis	1/665	34/18722	0.707925057493714	0.783430758348643	PTEN	1
GO:0086019	cell-cell signaling involved in cardiac conduction	1/665	34/18722	0.707925057493714	0.783430758348643	FLNA	1
GO:1904893	negative regulation of receptor signaling pathway via STAT	1/665	34/18722	0.707925057493714	0.783430758348643	SOCS3	1
GO:0031060	regulation of histone methylation	2/665	69/18722	0.708559727121555	0.783958558280082	LMNA/JARID2	2
GO:0006260	DNA replication	8/665	260/18722	0.709128297545635	0.784413006632941	JUN/RAC1/RRM2B/EGFR/RPA2/ACVRL1/CACYBP/S100A11	8
GO:0050773	regulation of dendrite development	3/665	103/18722	0.713430114859619	0.788995921417959	YWHAH/RHOA/SIPA1L1	3
GO:0060415	muscle tissue morphogenesis	2/665	70/18722	0.716012460353573	0.791675623572249	LY6E/SMAD7	2
GO:0009119	ribonucleoside metabolic process	1/665	35/18722	0.718318349272753	0.791934826061575	UPP1	1
GO:0010664	negative regulation of striated muscle cell apoptotic process	1/665	35/18722	0.718318349272753	0.791934826061575	NUPR1	1
GO:0031076	embryonic camera-type eye development	1/665	35/18722	0.718318349272753	0.791934826061575	CITED2	1
GO:0035633	maintenance of blood-brain barrier	1/665	35/18722	0.718318349272753	0.791934826061575	VEGFA	1
GO:0042462	eye photoreceptor cell development	1/665	35/18722	0.718318349272753	0.791934826061575	VEGFA	1
GO:0043243	positive regulation of protein-containing complex disassembly	1/665	35/18722	0.718318349272753	0.791934826061575	BNIP3	1
GO:0050654	chondroitin sulfate proteoglycan metabolic process	1/665	35/18722	0.718318349272753	0.791934826061575	CHST15	1
GO:0060236	regulation of mitotic spindle organization	1/665	35/18722	0.718318349272753	0.791934826061575	CHMP5	1
GO:0071108	protein K48-linked deubiquitination	1/665	35/18722	0.718318349272753	0.791934826061575	TNFAIP3	1
GO:0086005	ventricular cardiac muscle cell action potential	1/665	35/18722	0.718318349272753	0.791934826061575	KCNE1	1
GO:0090181	regulation of cholesterol metabolic process	1/665	35/18722	0.718318349272753	0.791934826061575	APOE	1
GO:1905207	regulation of cardiocyte differentiation	1/665	35/18722	0.718318349272753	0.791934826061575	EGFR	1
GO:1905898	positive regulation of response to endoplasmic reticulum stress	1/665	35/18722	0.718318349272753	0.791934826061575	FCGR2B	1
GO:0006986	response to unfolded protein	4/665	137/18722	0.721682855471404	0.795115005917286	EIF2AK2/ERO1A/ATF3/PPP1R15A	4
GO:0008203	cholesterol metabolic process	4/665	137/18722	0.721682855471404	0.795115005917286	APOE/OSBPL1A/SOAT1/INSIG2	4
GO:0060078	regulation of postsynaptic membrane potential	4/665	137/18722	0.721682855471404	0.795115005917286	PTEN/GABRB2/LRRK2/PTK2B	4
GO:0003208	cardiac ventricle morphogenesis	2/665	71/18722	0.723304451629136	0.796371981523439	LY6E/SMAD7	2
GO:0003281	ventricular septum development	2/665	71/18722	0.723304451629136	0.796371981523439	CITED2/SMAD7	2
GO:0050795	regulation of behavior	2/665	71/18722	0.723304451629136	0.796371981523439	APOE/ARRDC3	2
GO:0030178	negative regulation of Wnt signaling pathway	5/665	170/18722	0.726134879641291	0.799262845061223	APOE/DAB2/EGR1/RBX1/TLE3	5
GO:0000724	double-strand break repair via homologous recombination	4/665	138/18722	0.726939068367996	0.799262845061223	TERF2IP/RPA2/MORF4L1/SETD2	4
GO:0003203	endocardial cushion morphogenesis	1/665	36/18722	0.728342339091002	0.799262845061223	ACVRL1	1
GO:0006699	bile acid biosynthetic process	1/665	36/18722	0.728342339091002	0.799262845061223	OSBPL1A	1
GO:0009225	nucleotide-sugar metabolic process	1/665	36/18722	0.728342339091002	0.799262845061223	GUK1	1
GO:0010762	regulation of fibroblast migration	1/665	36/18722	0.728342339091002	0.799262845061223	RAC1	1
GO:0014046	dopamine secretion	1/665	36/18722	0.728342339091002	0.799262845061223	CXCL12	1
GO:0014059	regulation of dopamine secretion	1/665	36/18722	0.728342339091002	0.799262845061223	CXCL12	1
GO:0036314	response to sterol	1/665	36/18722	0.728342339091002	0.799262845061223	INSIG2	1
GO:0044743	protein transmembrane import into intracellular organelle	1/665	36/18722	0.728342339091002	0.799262845061223	DNAJC15	1
GO:0051354	negative regulation of oxidoreductase activity	1/665	36/18722	0.728342339091002	0.799262845061223	LRRK2	1
GO:0070670	response to interleukin-4	1/665	36/18722	0.728342339091002	0.799262845061223	NFIL3	1
GO:0070897	transcription preinitiation complex assembly	1/665	36/18722	0.728342339091002	0.799262845061223	PSMC6	1
GO:0097009	energy homeostasis	1/665	36/18722	0.728342339091002	0.799262845061223	CD36	1
GO:1901658	glycosyl compound catabolic process	1/665	36/18722	0.728342339091002	0.799262845061223	UPP1	1
GO:0001707	mesoderm formation	2/665	72/18722	0.730437697700662	0.801031632297505	KLF4/GPI	2
GO:0033045	regulation of sister chromatid segregation	2/665	72/18722	0.730437697700662	0.801031632297505	DUSP1/RB1	2
GO:1901880	negative regulation of protein depolymerization	2/665	72/18722	0.730437697700662	0.801031632297505	CAPG/GSN	2
GO:0099565	chemical synaptic transmission, postsynaptic	3/665	106/18722	0.731465093882049	0.801981362584113	PTEN/LRRK2/PTK2B	3
GO:0016579	protein deubiquitination	4/665	139/18722	0.732120977264895	0.802346473430326	OTUD1/TNFAIP3/USP18/TANK	4
GO:0051783	regulation of nuclear division	4/665	139/18722	0.732120977264895	0.802346473430326	DUSP1/UBE2B/IGF2/RB1	4
GO:0051656	establishment of organelle localization	12/665	390/18722	0.734442949195694	0.803661338092004	CD300A/MYO1G/UBE2B/TANC2/BLOC1S1/HMOX1/BLOC1S2/LRRK2/KIF5B/CFL1/CHMP5/RMDN1	12
GO:0007219	Notch signaling pathway	5/665	172/18722	0.735483857162447	0.803661338092004	NFKBIA/CFD/DTX3L/MMP14/APH1A	5
GO:0000725	recombinational repair	4/665	140/18722	0.737228805816204	0.803661338092004	TERF2IP/RPA2/MORF4L1/SETD2	4
GO:0007292	female gamete generation	4/665	140/18722	0.737228805816204	0.803661338092004	ANG/RGS2/PTK2B/HEXB	4
GO:0046165	alcohol biosynthetic process	4/665	140/18722	0.737228805816204	0.803661338092004	APOE/PTAFR/INSIG2/PTK2B	4
GO:0010927	cellular component assembly involved in morphogenesis	3/665	107/18722	0.737274819414397	0.803661338092004	CD9/PLEC/TLR2	3
GO:0009166	nucleotide catabolic process	2/665	73/18722	0.737414256391426	0.803661338092004	TYMP/UPP1	2
GO:0032456	endocytic recycling	2/665	73/18722	0.737414256391426	0.803661338092004	RAB8A/RAB13	2
GO:0042274	ribosomal small subunit biogenesis	2/665	73/18722	0.737414256391426	0.803661338092004	RPS27L/LSM6	2
GO:0051937	catecholamine transport	2/665	73/18722	0.737414256391426	0.803661338092004	LY6E/CXCL12	2
GO:0061035	regulation of cartilage development	2/665	73/18722	0.737414256391426	0.803661338092004	ACVRL1/SMAD7	2
GO:0072088	nephron epithelium morphogenesis	2/665	73/18722	0.737414256391426	0.803661338092004	VEGFA/STAT1	2
GO:1904427	positive regulation of calcium ion transmembrane transport	2/665	73/18722	0.737414256391426	0.803661338092004	CALM1/CALM3	2
GO:0090068	positive regulation of cell cycle process	7/665	236/18722	0.737510305879444	0.803661338092004	PLSCR1/UBE2B/ANXA1/RHOA/EGFR/IGF2/RB1	7
GO:0000154	rRNA modification	1/665	37/18722	0.738010130191531	0.803661338092004	NOP10	1
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1/665	37/18722	0.738010130191531	0.803661338092004	HELZ2	1
GO:0001990	regulation of systemic arterial blood pressure by hormone	1/665	37/18722	0.738010130191531	0.803661338092004	RHOA	1
GO:0003176	aortic valve development	1/665	37/18722	0.738010130191531	0.803661338092004	RB1	1
GO:0006862	nucleotide transport	1/665	37/18722	0.738010130191531	0.803661338092004	SLC25A19	1
GO:0031646	positive regulation of nervous system process	1/665	37/18722	0.738010130191531	0.803661338092004	PTAFR	1
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	1/665	37/18722	0.738010130191531	0.803661338092004	SULF2	1
GO:0042178	xenobiotic catabolic process	1/665	37/18722	0.738010130191531	0.803661338092004	ACSL1	1
GO:0043029	T cell homeostasis	1/665	37/18722	0.738010130191531	0.803661338092004	TSC22D3	1
GO:0043368	positive T cell selection	1/665	37/18722	0.738010130191531	0.803661338092004	CD74	1
GO:0060416	response to growth hormone	1/665	37/18722	0.738010130191531	0.803661338092004	CACYBP	1
GO:0097484	dendrite extension	1/665	37/18722	0.738010130191531	0.803661338092004	CXCR4	1
GO:1902745	positive regulation of lamellipodium organization	1/665	37/18722	0.738010130191531	0.803661338092004	RAC1	1
GO:1904358	positive regulation of telomere maintenance via telomere lengthening	1/665	37/18722	0.738010130191531	0.803661338092004	HNRNPA1	1
GO:1905332	positive regulation of morphogenesis of an epithelium	1/665	37/18722	0.738010130191531	0.803661338092004	VEGFA	1
GO:1901617	organic hydroxy compound biosynthetic process	7/665	237/18722	0.741443111489888	0.80722283989151	APOE/NR4A2/PTAFR/OSBPL1A/INSIG2/PTK2B/HSD17B1	7
GO:0003002	regionalization	10/665	331/18722	0.742633307694893	0.808341554805873	BHLHE40/MAFB/ABI1/CITED2/ITGAM/AIDA/ACVRL1/FBXL15/C1QA/NRP1	10
GO:0034440	lipid oxidation	3/665	108/18722	0.742984661331745	0.808369913927051	ALOX5/HSD17B4/IRS2	3
GO:0140053	mitochondrial gene expression	3/665	108/18722	0.742984661331745	0.808369913927051	MRPS18B/GATC/MRPL43	3
GO:0006635	fatty acid beta-oxidation	2/665	74/18722	0.744236239754164	0.809377267303762	HSD17B4/IRS2	2
GO:0046470	phosphatidylcholine metabolic process	2/665	74/18722	0.744236239754164	0.809377267303762	CAPN2/APOC1	2
GO:0072006	nephron development	4/665	142/18722	0.74722327630488	0.811149110511844	VEGFA/SULF2/STAT1/EGR1	4
GO:0002385	mucosal immune response	1/665	38/18722	0.747334361576204	0.811149110511844	RPL39	1
GO:0007094	mitotic spindle assembly checkpoint signaling	1/665	38/18722	0.747334361576204	0.811149110511844	DUSP1	1
GO:0010613	positive regulation of cardiac muscle hypertrophy	1/665	38/18722	0.747334361576204	0.811149110511844	HAMP	1
GO:0051930	regulation of sensory perception of pain	1/665	38/18722	0.747334361576204	0.811149110511844	PTAFR	1
GO:0071173	spindle assembly checkpoint signaling	1/665	38/18722	0.747334361576204	0.811149110511844	DUSP1	1
GO:0071174	mitotic spindle checkpoint signaling	1/665	38/18722	0.747334361576204	0.811149110511844	DUSP1	1
GO:0071392	cellular response to estradiol stimulus	1/665	38/18722	0.747334361576204	0.811149110511844	EGFR	1
GO:0071398	cellular response to fatty acid	1/665	38/18722	0.747334361576204	0.811149110511844	PTAFR	1
GO:0006024	glycosaminoglycan biosynthetic process	2/665	75/18722	0.750905807637336	0.814847568549686	B3GNT7/CHST15	2
GO:0007088	regulation of mitotic nuclear division	3/665	110/18722	0.754107601312284	0.818143370120509	DUSP1/IGF2/RB1	3
GO:0014742	positive regulation of muscle hypertrophy	1/665	39/18722	0.756327224429545	0.818407643242944	HAMP	1
GO:0016233	telomere capping	1/665	39/18722	0.756327224429545	0.818407643242944	TERF2IP	1
GO:0016572	histone phosphorylation	1/665	39/18722	0.756327224429545	0.818407643242944	UBE2B	1
GO:0031507	heterochromatin assembly	1/665	39/18722	0.756327224429545	0.818407643242944	ZNFX1	1
GO:0031577	spindle checkpoint signaling	1/665	39/18722	0.756327224429545	0.818407643242944	DUSP1	1
GO:0046461	neutral lipid catabolic process	1/665	39/18722	0.756327224429545	0.818407643242944	ABHD5	1
GO:0046464	acylglycerol catabolic process	1/665	39/18722	0.756327224429545	0.818407643242944	ABHD5	1
GO:0051931	regulation of sensory perception	1/665	39/18722	0.756327224429545	0.818407643242944	PTAFR	1
GO:0086091	regulation of heart rate by cardiac conduction	1/665	39/18722	0.756327224429545	0.818407643242944	KCNE1	1
GO:0090224	regulation of spindle organization	1/665	39/18722	0.756327224429545	0.818407643242944	CHMP5	1
GO:1902742	apoptotic process involved in development	1/665	39/18722	0.756327224429545	0.818407643242944	SPI1	1
GO:1903115	regulation of actin filament-based movement	1/665	39/18722	0.756327224429545	0.818407643242944	PDPN	1
GO:0008652	cellular amino acid biosynthetic process	2/665	76/18722	0.757425161638793	0.818882543690407	GLUL/SLC1A3	2
GO:0021536	diencephalon development	2/665	76/18722	0.757425161638793	0.818882543690407	NR4A2/NRP1	2
GO:0071426	ribonucleoprotein complex export from nucleus	2/665	76/18722	0.757425161638793	0.818882543690407	SSB/SETD2	2
GO:0072028	nephron morphogenesis	2/665	76/18722	0.757425161638793	0.818882543690407	VEGFA/STAT1	2
GO:0000380	alternative mRNA splicing, via spliceosome	2/665	77/18722	0.763796539427504	0.824873707291329	SLU7/HNRNPA1	2
GO:0002200	somatic diversification of immune receptors	2/665	77/18722	0.763796539427504	0.824873707291329	IL27RA/TFRC	2
GO:0031016	pancreas development	2/665	77/18722	0.763796539427504	0.824873707291329	ANXA1/IGF2	2
GO:0048644	muscle organ morphogenesis	2/665	77/18722	0.763796539427504	0.824873707291329	LY6E/SMAD7	2
GO:0071166	ribonucleoprotein complex localization	2/665	77/18722	0.763796539427504	0.824873707291329	SSB/SETD2	2
GO:0007339	binding of sperm to zona pellucida	1/665	40/18722	0.765000477962402	0.824919152847285	ALDOA	1
GO:0031111	negative regulation of microtubule polymerization or depolymerization	1/665	40/18722	0.765000477962402	0.824919152847285	MAPRE1	1
GO:0032094	response to food	1/665	40/18722	0.765000477962402	0.824919152847285	PLEC	1
GO:0035329	hippo signaling	1/665	40/18722	0.765000477962402	0.824919152847285	MOB1A	1
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	1/665	40/18722	0.765000477962402	0.824919152847285	DUSP1	1
GO:0070266	necroptotic process	1/665	40/18722	0.765000477962402	0.824919152847285	YBX3	1
GO:1901661	quinone metabolic process	1/665	40/18722	0.765000477962402	0.824919152847285	VKORC1	1
GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	4/665	146/18722	0.766336508714621	0.826033539284968	ADM/GNAQ/ADGRE5/ARRDC3	4
GO:0006399	tRNA metabolic process	5/665	179/18722	0.766366327895973	0.826033539284968	SSB/ANG/GATC/RPP30/LSM6	5
GO:0009064	glutamine family amino acid metabolic process	2/665	78/18722	0.7700222094149	0.829794098176941	GLUL/DDAH2	2
GO:0060041	retina development in camera-type eye	4/665	147/18722	0.770934578825123	0.830597194181847	MERTK/ACVRL1/CYP1B1/NRP1	4
GO:0002251	organ or tissue specific immune response	1/665	41/18722	0.773365464695889	0.832494338214981	RPL39	1
GO:0009167	purine ribonucleoside monophosphate metabolic process	1/665	41/18722	0.773365464695889	0.832494338214981	GUK1	1
GO:0055023	positive regulation of cardiac muscle tissue growth	1/665	41/18722	0.773365464695889	0.832494338214981	HAMP	1
GO:1905314	semi-lunar valve development	1/665	41/18722	0.773365464695889	0.832494338214981	RB1	1
GO:0006479	protein methylation	5/665	181/18722	0.774670075946223	0.833537622310615	BTG1/SNRPB/LMNA/JARID2/SETD2	5
GO:0008213	protein alkylation	5/665	181/18722	0.774670075946223	0.833537622310615	BTG1/SNRPB/LMNA/JARID2/SETD2	5
GO:0051261	protein depolymerization	3/665	114/18722	0.775188988909289	0.833847512232292	CAPG/GSN/CFL1	3
GO:0050905	neuromuscular process	4/665	148/18722	0.775461408760091	0.833847512232292	SLC1A3/PTEN/HEXB/NR4A1	4
GO:0070507	regulation of microtubule cytoskeleton organization	4/665	148/18722	0.775461408760091	0.833847512232292	MAPRE1/RAC1/RHOA/CHMP5	4
GO:0001895	retina homeostasis	2/665	79/18722	0.776104465758211	0.833997663744499	B2M/LYZ	2
GO:0006023	aminoglycan biosynthetic process	2/665	79/18722	0.776104465758211	0.833997663744499	B3GNT7/CHST15	2
GO:0006029	proteoglycan metabolic process	2/665	79/18722	0.776104465758211	0.833997663744499	SULF2/CHST15	2
GO:0034968	histone lysine methylation	3/665	115/18722	0.780221810950377	0.83700918798935	LMNA/JARID2/SETD2	3
GO:0042471	ear morphogenesis	3/665	115/18722	0.780221810950377	0.83700918798935	MAFB/INSIG2/EPHB2	3
GO:1901989	positive regulation of cell cycle phase transition	3/665	115/18722	0.780221810950377	0.83700918798935	ANXA1/EGFR/RB1	3
GO:0000413	protein peptidyl-prolyl isomerization	1/665	42/18722	0.781433125205349	0.83700918798935	FKBP5	1
GO:0019432	triglyceride biosynthetic process	1/665	42/18722	0.781433125205349	0.83700918798935	ACSL1	1
GO:0021795	cerebral cortex cell migration	1/665	42/18722	0.781433125205349	0.83700918798935	RHOA	1
GO:0032467	positive regulation of cytokinesis	1/665	42/18722	0.781433125205349	0.83700918798935	RHOA	1
GO:0043507	positive regulation of JUN kinase activity	1/665	42/18722	0.781433125205349	0.83700918798935	PTK2B	1
GO:0045047	protein targeting to ER	1/665	42/18722	0.781433125205349	0.83700918798935	SEC61G	1
GO:0045214	sarcomere organization	1/665	42/18722	0.781433125205349	0.83700918798935	PLEC	1
GO:0045292	mRNA cis splicing, via spliceosome	1/665	42/18722	0.781433125205349	0.83700918798935	CWC15	1
GO:0071312	cellular response to alkaloid	1/665	42/18722	0.781433125205349	0.83700918798935	SLC1A3	1
GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	1/665	42/18722	0.781433125205349	0.83700918798935	DUSP1	1
GO:1904037	positive regulation of epithelial cell apoptotic process	1/665	42/18722	0.781433125205349	0.83700918798935	GSN	1
GO:2001222	regulation of neuron migration	1/665	42/18722	0.781433125205349	0.83700918798935	FLNA	1
GO:0032204	regulation of telomere maintenance	2/665	80/18722	0.782045623679013	0.837304340733454	TERF2IP/HNRNPA1	2
GO:0120193	tight junction organization	2/665	80/18722	0.782045623679013	0.837304340733454	PLEC/RAB13	2
GO:0007051	spindle organization	5/665	184/18722	0.786699604142123	0.842105757610672	MAPRE1/FLNA/RHOA/CHMP5/RMDN1	5
GO:0048592	eye morphogenesis	4/665	151/18722	0.788619238384543	0.842981655135742	VEGFA/CITED2/FBN2/EPHB2	4
GO:0048754	branching morphogenesis of an epithelial tube	4/665	151/18722	0.788619238384543	0.842981655135742	VEGFA/CTSH/MMP14/NRP1	4
GO:0001504	neurotransmitter uptake	1/665	43/18722	0.789214012343382	0.842981655135742	SLC1A3	1
GO:0006284	base-excision repair	1/665	43/18722	0.789214012343382	0.842981655135742	RPA2	1
GO:0010171	body morphogenesis	1/665	43/18722	0.789214012343382	0.842981655135742	TIPARP	1
GO:0030517	negative regulation of axon extension	1/665	43/18722	0.789214012343382	0.842981655135742	NRP1	1
GO:0033046	negative regulation of sister chromatid segregation	1/665	43/18722	0.789214012343382	0.842981655135742	DUSP1	1
GO:0033048	negative regulation of mitotic sister chromatid segregation	1/665	43/18722	0.789214012343382	0.842981655135742	DUSP1	1
GO:0034661	ncRNA catabolic process	1/665	43/18722	0.789214012343382	0.842981655135742	ANG	1
GO:2000816	negative regulation of mitotic sister chromatid separation	1/665	43/18722	0.789214012343382	0.842981655135742	DUSP1	1
GO:0008543	fibroblast growth factor receptor signaling pathway	2/665	82/18722	0.793513984451214	0.847210419489266	SULF2/SHOC2	2
GO:0043242	negative regulation of protein-containing complex disassembly	2/665	82/18722	0.793513984451214	0.847210419489266	CAPG/GSN	2
GO:0002066	columnar/cuboidal epithelial cell development	1/665	44/18722	0.796718304960313	0.849354349131865	CDKN1A	1
GO:0002792	negative regulation of peptide secretion	1/665	44/18722	0.796718304960313	0.849354349131865	CD74	1
GO:0009126	purine nucleoside monophosphate metabolic process	1/665	44/18722	0.796718304960313	0.849354349131865	GUK1	1
GO:0043039	tRNA aminoacylation	1/665	44/18722	0.796718304960313	0.849354349131865	GATC	1
GO:0048806	genitalia development	1/665	44/18722	0.796718304960313	0.849354349131865	MERTK	1
GO:0051150	regulation of smooth muscle cell differentiation	1/665	44/18722	0.796718304960313	0.849354349131865	SOD2	1
GO:0060324	face development	1/665	44/18722	0.796718304960313	0.849354349131865	TIPARP	1
GO:0007338	single fertilization	4/665	153/18722	0.797044039064189	0.849519381117096	LHFPL2/CD9/ALDOA/HEXB	4
GO:0001510	RNA methylation	2/665	83/18722	0.799045885031611	0.850923087338141	LARP7/ZC3H13	2
GO:0046785	microtubule polymerization	2/665	83/18722	0.799045885031611	0.850923087338141	MAPRE1/RAC1	2
GO:0050886	endocrine process	2/665	83/18722	0.799045885031611	0.850923087338141	CGA/RHOA	2
GO:1901292	nucleoside phosphate catabolic process	2/665	83/18722	0.799045885031611	0.850923087338141	TYMP/UPP1	2
GO:0003009	skeletal muscle contraction	1/665	45/18722	0.80395582113985	0.853464798365488	NR4A1	1
GO:0010824	regulation of centrosome duplication	1/665	45/18722	0.80395582113985	0.853464798365488	CHMP5	1
GO:0031670	cellular response to nutrient	1/665	45/18722	0.80395582113985	0.853464798365488	HMOX1	1
GO:0032309	icosanoid secretion	1/665	45/18722	0.80395582113985	0.853464798365488	ANXA1	1
GO:0035384	thioester biosynthetic process	1/665	45/18722	0.80395582113985	0.853464798365488	ACSL1	1
GO:0043038	amino acid activation	1/665	45/18722	0.80395582113985	0.853464798365488	GATC	1
GO:0045910	negative regulation of DNA recombination	1/665	45/18722	0.80395582113985	0.853464798365488	TERF2IP	1
GO:0046189	phenol-containing compound biosynthetic process	1/665	45/18722	0.80395582113985	0.853464798365488	NR4A2	1
GO:0051985	negative regulation of chromosome segregation	1/665	45/18722	0.80395582113985	0.853464798365488	DUSP1	1
GO:0060119	inner ear receptor cell development	1/665	45/18722	0.80395582113985	0.853464798365488	GABRB2	1
GO:0060421	positive regulation of heart growth	1/665	45/18722	0.80395582113985	0.853464798365488	HAMP	1
GO:0071616	acyl-CoA biosynthetic process	1/665	45/18722	0.80395582113985	0.853464798365488	ACSL1	1
GO:1905819	negative regulation of chromosome separation	1/665	45/18722	0.80395582113985	0.853464798365488	DUSP1	1
GO:0006304	DNA modification	3/665	120/18722	0.804008488118152	0.853464798365488	FOS/SPI1/KDM1B	3
GO:0048593	camera-type eye morphogenesis	3/665	120/18722	0.804008488118152	0.853464798365488	VEGFA/CITED2/EPHB2	3
GO:0006835	dicarboxylic acid transport	2/665	84/18722	0.804446075244603	0.853564687012313	SLC1A3/KMO	2
GO:0015844	monoamine transport	2/665	84/18722	0.804446075244603	0.853564687012313	LY6E/CXCL12	2
GO:0010970	transport along microtubule	4/665	155/18722	0.805196298007047	0.854178356690506	BLOC1S1/BLOC1S2/DST/KIF5B	4
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	9/665	320/18722	0.806090709323411	0.854762284048934	SNRPB/CWC15/SLU7/NCL/LARP7/ZCRB1/SF3B6/HNRNPA1/LSM6	9
GO:0000398	mRNA splicing, via spliceosome	9/665	320/18722	0.806090709323411	0.854762284048934	SNRPB/CWC15/SLU7/NCL/LARP7/ZCRB1/SF3B6/HNRNPA1/LSM6	9
GO:0043244	regulation of protein-containing complex disassembly	3/665	121/18722	0.808497452907129	0.856948675826067	CAPG/GSN/BNIP3	3
GO:0048706	embryonic skeletal system development	3/665	121/18722	0.808497452907129	0.856948675826067	SULF2/MMP14/SETD2	3
GO:0009566	fertilization	5/665	190/18722	0.809255353836406	0.857569106304251	LHFPL2/CD9/ALDOA/YBX3/HEXB	5
GO:0030433	ubiquitin-dependent ERAD pathway	2/665	85/18722	0.80971691536176	0.857704208109401	PSMC6/RNF5	2
GO:0010830	regulation of myotube differentiation	1/665	46/18722	0.810936030967017	0.857704208109401	MMP14	1
GO:0031018	endocrine pancreas development	1/665	46/18722	0.810936030967017	0.857704208109401	ANXA1	1
GO:0033047	regulation of mitotic sister chromatid segregation	1/665	46/18722	0.810936030967017	0.857704208109401	DUSP1	1
GO:0043462	regulation of ATPase activity	1/665	46/18722	0.810936030967017	0.857704208109401	GABARAPL2	1
GO:0046839	phospholipid dephosphorylation	1/665	46/18722	0.810936030967017	0.857704208109401	PTEN	1
GO:0050919	negative chemotaxis	1/665	46/18722	0.810936030967017	0.857704208109401	RHOA	1
GO:0070828	heterochromatin organization	1/665	46/18722	0.810936030967017	0.857704208109401	ZNFX1	1
GO:0072599	establishment of protein localization to endoplasmic reticulum	1/665	46/18722	0.810936030967017	0.857704208109401	SEC61G	1
GO:1902600	proton transmembrane transport	4/665	157/18722	0.813080698949254	0.859789590165487	ATP6V1F/ATP6V1G1/ATP6V1B2/COX5B	4
GO:0003231	cardiac ventricle development	3/665	123/18722	0.817215464892942	0.863171262140833	LY6E/CITED2/SMAD7	3
GO:0000375	RNA splicing, via transesterification reactions	9/665	324/18722	0.817233250621046	0.863171262140833	SNRPB/CWC15/SLU7/NCL/LARP7/ZCRB1/SF3B6/HNRNPA1/LSM6	9
GO:0001754	eye photoreceptor cell differentiation	1/665	47/18722	0.817668068844878	0.863171262140833	VEGFA	1
GO:0006998	nuclear envelope organization	1/665	47/18722	0.817668068844878	0.863171262140833	LMNA	1
GO:0009261	ribonucleotide catabolic process	1/665	47/18722	0.817668068844878	0.863171262140833	UPP1	1
GO:0045332	phospholipid translocation	1/665	47/18722	0.817668068844878	0.863171262140833	PLSCR1	1
GO:0101023	vascular endothelial cell proliferation	1/665	47/18722	0.817668068844878	0.863171262140833	IGF2	1
GO:1905562	regulation of vascular endothelial cell proliferation	1/665	47/18722	0.817668068844878	0.863171262140833	IGF2	1
GO:1901879	regulation of protein depolymerization	2/665	87/18722	0.819879977244587	0.865322464834486	CAPG/GSN	2
GO:0046488	phosphatidylinositol metabolic process	4/665	159/18722	0.82070214897689	0.866006301574341	PIP4K2A/PTEN/SOCS3/PIK3CB	4
GO:0006111	regulation of gluconeogenesis	1/665	48/18722	0.82416074537597	0.868733595868202	FBP1	1
GO:0032527	protein exit from endoplasmic reticulum	1/665	48/18722	0.82416074537597	0.868733595868202	CD81	1
GO:0042908	xenobiotic transport	1/665	48/18722	0.82416074537597	0.868733595868202	ABCC3	1
GO:0044458	motile cilium assembly	1/665	48/18722	0.82416074537597	0.868733595868202	UBE2B	1
GO:0045839	negative regulation of mitotic nuclear division	1/665	48/18722	0.82416074537597	0.868733595868202	DUSP1	1
GO:0031110	regulation of microtubule polymerization or depolymerization	2/665	88/18722	0.824776901954717	0.869198728311056	MAPRE1/RAC1	2
GO:0006376	mRNA splice site selection	1/665	49/18722	0.830422558823811	0.873666409262138	SLU7	1
GO:0007602	phototransduction	1/665	49/18722	0.830422558823811	0.873666409262138	GNAQ	1
GO:0008206	bile acid metabolic process	1/665	49/18722	0.830422558823811	0.873666409262138	OSBPL1A	1
GO:0042461	photoreceptor cell development	1/665	49/18722	0.830422558823811	0.873666409262138	VEGFA	1
GO:0060986	endocrine hormone secretion	1/665	49/18722	0.830422558823811	0.873666409262138	CGA	1
GO:0072091	regulation of stem cell proliferation	1/665	49/18722	0.830422558823811	0.873666409262138	EIF2AK2	1
GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	1/665	49/18722	0.830422558823811	0.873666409262138	JUN	1
GO:1990573	potassium ion import across plasma membrane	1/665	49/18722	0.830422558823811	0.873666409262138	WNK1	1
GO:0008033	tRNA processing	3/665	127/18722	0.833642538415036	0.876868447814334	SSB/RPP30/LSM6	3
GO:0042475	odontogenesis of dentin-containing tooth	2/665	90/18722	0.834213230429188	0.877283062893158	ADM/FAM20C	2
GO:0000387	spliceosomal snRNP assembly	1/665	50/18722	0.836461706169292	0.878346646875424	SNRPB	1
GO:0007632	visual behavior	1/665	50/18722	0.836461706169292	0.878346646875424	DYNLRB1	1
GO:0015872	dopamine transport	1/665	50/18722	0.836461706169292	0.878346646875424	CXCL12	1
GO:0030490	maturation of SSU-rRNA	1/665	50/18722	0.836461706169292	0.878346646875424	LSM6	1
GO:0051646	mitochondrion localization	1/665	50/18722	0.836461706169292	0.878346646875424	LRRK2	1
GO:0060425	lung morphogenesis	1/665	50/18722	0.836461706169292	0.878346646875424	CTSH	1
GO:0090102	cochlea development	1/665	50/18722	0.836461706169292	0.878346646875424	GABRB2	1
GO:0032259	methylation	10/665	364/18722	0.836815368800993	0.878532400283256	BTG1/SNRPB/FOS/LMNA/LARP7/SPI1/KDM1B/JARID2/ZC3H13/SETD2	10
GO:0001657	ureteric bud development	2/665	91/18722	0.838757274795204	0.880199251632636	VEGFA/SMAD7	2
GO:0072080	nephron tubule development	2/665	91/18722	0.838757274795204	0.880199251632636	VEGFA/STAT1	2
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	1/665	51/18722	0.842286093776266	0.882784033333624	DNAJC15	1
GO:0009584	detection of visible light	1/665	51/18722	0.842286093776266	0.882784033333624	GNAQ	1
GO:0045661	regulation of myoblast differentiation	1/665	51/18722	0.842286093776266	0.882784033333624	BTG1	1
GO:0045668	negative regulation of osteoblast differentiation	1/665	51/18722	0.842286093776266	0.882784033333624	TOB1	1
GO:0051293	establishment of spindle localization	1/665	51/18722	0.842286093776266	0.882784033333624	CFL1	1
GO:0051339	regulation of lyase activity	1/665	51/18722	0.842286093776266	0.882784033333624	CAP1	1
GO:0016570	histone modification	13/665	463/18722	0.842685986119466	0.882984806466862	VEGFA/UBE2B/DTX3L/LMNA/LRRK2/SPI1/KDM1B/IGF2/MORF4L1/PHB/JARID2/PER1/SETD2	13
GO:0072163	mesonephric epithelium development	2/665	92/18722	0.843188308147229	0.882984806466862	VEGFA/SMAD7	2
GO:0072164	mesonephric tubule development	2/665	92/18722	0.843188308147229	0.882984806466862	VEGFA/SMAD7	2
GO:1903351	cellular response to dopamine	2/665	92/18722	0.843188308147229	0.882984806466862	FLNA/LRRK2	2
GO:0006352	DNA-templated transcription, initiation	3/665	130/18722	0.845115285801095	0.884816298805865	JUN/PSMC6/RSF1	3
GO:0033108	mitochondrial respiratory chain complex assembly	2/665	93/18722	0.847508610751262	0.88624177454683	SCO2/COX16	2
GO:1903350	response to dopamine	2/665	93/18722	0.847508610751262	0.88624177454683	FLNA/LRRK2	2
GO:0046395	carboxylic acid catabolic process	6/665	236/18722	0.847831769482874	0.88624177454683	IL4I1/GLUL/HSD17B4/IRS2/DDAH2/KMO	6
GO:0007129	homologous chromosome pairing at meiosis	1/665	52/18722	0.847903347680116	0.88624177454683	UBE2B	1
GO:0032206	positive regulation of telomere maintenance	1/665	52/18722	0.847903347680116	0.88624177454683	HNRNPA1	1
GO:0034204	lipid translocation	1/665	52/18722	0.847903347680116	0.88624177454683	PLSCR1	1
GO:0035196	production of miRNAs involved in gene silencing by miRNA	1/665	52/18722	0.847903347680116	0.88624177454683	EGFR	1
GO:0072132	mesenchyme morphogenesis	1/665	52/18722	0.847903347680116	0.88624177454683	ACVRL1	1
GO:0009451	RNA modification	4/665	167/18722	0.848662826774743	0.886603031864336	SSB/NOP10/LARP7/ZC3H13	4
GO:0018022	peptidyl-lysine methylation	3/665	131/18722	0.848784150022235	0.886603031864336	LMNA/JARID2/SETD2	3
GO:0050853	B cell receptor signaling pathway	3/665	131/18722	0.848784150022235	0.886603031864336	FCGR2B/CD300A/CD81	3
GO:0010389	regulation of G2/M transition of mitotic cell cycle	2/665	94/18722	0.85172044372925	0.889094664230271	CDKN1A/FOXN3	2
GO:0048704	embryonic skeletal system morphogenesis	2/665	94/18722	0.85172044372925	0.889094664230271	MMP14/SETD2	2
GO:0061326	renal tubule development	2/665	94/18722	0.85172044372925	0.889094664230271	VEGFA/STAT1	2
GO:0000070	mitotic sister chromatid segregation	4/665	168/18722	0.851885068624658	0.889094664230271	DUSP1/RB1/CHMP5/RMDN1	4
GO:0006310	DNA recombination	8/665	305/18722	0.852586677881208	0.889640098481966	TERF2IP/UBE2B/RPA2/IL7R/IL27RA/TFRC/MORF4L1/SETD2	8
GO:0032210	regulation of telomere maintenance via telomerase	1/665	53/18722	0.853320823512613	0.890219247031421	HNRNPA1	1
GO:0018394	peptidyl-lysine acetylation	4/665	169/18722	0.855049014758841	0.891834963977217	BLOC1S1/SPI1/MORF4L1/PER1	4
GO:0008593	regulation of Notch signaling pathway	2/665	95/18722	0.855826047542366	0.892343495410757	NFKBIA/MMP14	2
GO:0006997	nucleus organization	3/665	133/18722	0.855895662499614	0.892343495410757	LMNA/PLEC/CHMP5	3
GO:0031050	dsRNA processing	1/665	54/18722	0.858545616075906	0.893892179134638	EGFR	1
GO:0035065	regulation of histone acetylation	1/665	54/18722	0.858545616075906	0.893892179134638	SPI1	1
GO:0060350	endochondral bone morphogenesis	1/665	54/18722	0.858545616075906	0.893892179134638	MMP14	1
GO:0070918	production of small RNA involved in gene silencing by RNA	1/665	54/18722	0.858545616075906	0.893892179134638	EGFR	1
GO:0072348	sulfur compound transport	1/665	54/18722	0.858545616075906	0.893892179134638	SLC25A19	1
GO:0016054	organic acid catabolic process	6/665	240/18722	0.858640093196934	0.893892179134638	IL4I1/GLUL/HSD17B4/IRS2/DDAH2/KMO	6
GO:0032886	regulation of microtubule-based process	6/665	240/18722	0.858640093196934	0.893892179134638	ATF5/MAPRE1/RAC1/RHOA/DIAPH1/CHMP5	6
GO:0001823	mesonephros development	2/665	96/18722	0.859827640605848	0.894566333224003	VEGFA/SMAD7	2
GO:0006637	acyl-CoA metabolic process	2/665	96/18722	0.859827640605848	0.894566333224003	ACSL1/HSD17B4	2
GO:0035383	thioester metabolic process	2/665	96/18722	0.859827640605848	0.894566333224003	ACSL1/HSD17B4	2
GO:0009581	detection of external stimulus	3/665	135/18722	0.862713187859065	0.897380607714431	CXCR4/GNAQ/CXCL12	3
GO:0003179	heart valve morphogenesis	1/665	55/18722	0.863584568578023	0.897911151847861	RB1	1
GO:0006414	translational elongation	1/665	55/18722	0.863584568578023	0.897911151847861	CPEB2	1
GO:0043624	cellular protein complex disassembly	3/665	136/18722	0.866014564686392	0.90006114313914	CAPG/GSN/CFL1	3
GO:0072073	kidney epithelium development	3/665	136/18722	0.866014564686392	0.90006114313914	VEGFA/STAT1/SMAD7	3
GO:0043473	pigmentation	2/665	98/18722	0.867527550466155	0.901267086920643	BLOC1S1/BLOC1S2	2
GO:0001658	branching involved in ureteric bud morphogenesis	1/665	56/18722	0.868444281541843	0.901267086920643	VEGFA	1
GO:0030166	proteoglycan biosynthetic process	1/665	56/18722	0.868444281541843	0.901267086920643	CHST15	1
GO:0050433	regulation of catecholamine secretion	1/665	56/18722	0.868444281541843	0.901267086920643	CXCL12	1
GO:0051653	spindle localization	1/665	56/18722	0.868444281541843	0.901267086920643	CFL1	1
GO:0051784	negative regulation of nuclear division	1/665	56/18722	0.868444281541843	0.901267086920643	DUSP1	1
GO:0055078	sodium ion homeostasis	1/665	56/18722	0.868444281541843	0.901267086920643	SLC1A3	1
GO:0050684	regulation of mRNA processing	3/665	137/18722	0.869245871609116	0.90191064340236	NCL/LARP7/HNRNPA1	3
GO:0009582	detection of abiotic stimulus	3/665	138/18722	0.872408245014474	0.904997220720185	CXCR4/GNAQ/CXCL12	3
GO:0050879	multicellular organismal movement	1/665	57/18722	0.873131121399052	0.904997220720185	NR4A1	1
GO:0050881	musculoskeletal movement	1/665	57/18722	0.873131121399052	0.904997220720185	NR4A1	1
GO:0050891	multicellular organismal water homeostasis	1/665	57/18722	0.873131121399052	0.904997220720185	PLEC	1
GO:1902017	regulation of cilium assembly	1/665	57/18722	0.873131121399052	0.904997220720185	ATG3	1
GO:0009062	fatty acid catabolic process	2/665	100/18722	0.874837434668649	0.906576741097411	HSD17B4/IRS2	2
GO:0007131	reciprocal meiotic recombination	1/665	58/18722	0.877651228780227	0.908734709799527	UBE2B	1
GO:0035904	aorta development	1/665	58/18722	0.877651228780227	0.908734709799527	ACVRL1	1
GO:0097035	regulation of membrane lipid distribution	1/665	58/18722	0.877651228780227	0.908734709799527	PLSCR1	1
GO:0140527	reciprocal homologous recombination	1/665	58/18722	0.877651228780227	0.908734709799527	UBE2B	1
GO:0016571	histone methylation	3/665	141/18722	0.88149306092072	0.912487992665154	LMNA/JARID2/SETD2	3
GO:0006672	ceramide metabolic process	2/665	102/18722	0.881774132732673	0.912487992665154	ST8SIA4/HEXB	2
GO:0006406	mRNA export from nucleus	1/665	59/18722	0.88201052651175	0.912487992665154	SETD2	1
GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus	1/665	59/18722	0.88201052651175	0.912487992665154	SETD2	1
GO:0048562	embryonic organ morphogenesis	7/665	285/18722	0.883733177973671	0.914079894803152	MAFB/CITED2/FBN2/INSIG2/MMP14/EPHB2/SETD2	7
GO:0046467	membrane lipid biosynthetic process	3/665	142/18722	0.884390969941206	0.914569937704493	ST8SIA4/HACD4/B3GNT5	3
GO:0019395	fatty acid oxidation	2/665	103/18722	0.88510767764105	0.914771367489962	HSD17B4/IRS2	2
GO:0030148	sphingolipid biosynthetic process	2/665	103/18722	0.88510767764105	0.914771367489962	ST8SIA4/HACD4	2
GO:0006302	double-strand break repair	6/665	251/18722	0.885137928824794	0.914771367489962	TERF2IP/DTX3L/PARP9/RPA2/MORF4L1/SETD2	6
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	1/665	60/18722	0.88621472732993	0.915503470137134	HNRNPA1	1
GO:0035825	homologous recombination	1/665	60/18722	0.88621472732993	0.915503470137134	UBE2B	1
GO:0140014	mitotic nuclear division	7/665	287/18722	0.887868682955999	0.917021478447904	DUSP1/FLNA/RHOA/IGF2/RB1/CHMP5/RMDN1	7
GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	2/665	104/18722	0.888354037112877	0.917332134729067	FPR3/C5AR1	2
GO:0019748	secondary metabolic process	1/665	61/18722	0.890269341322299	0.918355879280163	CYP1B1	1
GO:0040014	regulation of multicellular organism growth	1/665	61/18722	0.890269341322299	0.918355879280163	IGF2	1
GO:0042255	ribosome assembly	1/665	61/18722	0.890269341322299	0.918355879280163	RPS27L	1
GO:1904356	regulation of telomere maintenance via telomere lengthening	1/665	61/18722	0.890269341322299	0.918355879280163	HNRNPA1	1
GO:1905515	non-motile cilium assembly	1/665	61/18722	0.890269341322299	0.918355879280163	MAPRE1	1
GO:0007062	sister chromatid cohesion	1/665	62/18722	0.894179683105734	0.921815603616573	RB1	1
GO:0060113	inner ear receptor cell differentiation	1/665	62/18722	0.894179683105734	0.921815603616573	GABRB2	1
GO:0060675	ureteric bud morphogenesis	1/665	62/18722	0.894179683105734	0.921815603616573	VEGFA	1
GO:0090596	sensory organ morphogenesis	6/665	256/18722	0.895721888279782	0.923213974440173	VEGFA/MAFB/CITED2/FBN2/INSIG2/EPHB2	6
GO:0036503	ERAD pathway	2/665	107/18722	0.897589611709157	0.923404897039288	PSMC6/RNF5	2
GO:0042303	molting cycle	2/665	107/18722	0.897589611709157	0.923404897039288	EGFR/PER1	2
GO:0042633	hair cycle	2/665	107/18722	0.897589611709157	0.923404897039288	EGFR/PER1	2
GO:0071868	cellular response to monoamine stimulus	2/665	107/18722	0.897589611709157	0.923404897039288	FLNA/LRRK2	2
GO:0071870	cellular response to catecholamine stimulus	2/665	107/18722	0.897589611709157	0.923404897039288	FLNA/LRRK2	2
GO:0001756	somitogenesis	1/665	63/18722	0.897950878750679	0.923404897039288	ABI1	1
GO:0001947	heart looping	1/665	63/18722	0.897950878750679	0.923404897039288	CITED2	1
GO:0030239	myofibril assembly	1/665	63/18722	0.897950878750679	0.923404897039288	PLEC	1
GO:0045143	homologous chromosome segregation	1/665	63/18722	0.897950878750679	0.923404897039288	UBE2B	1
GO:0072171	mesonephric tubule morphogenesis	1/665	63/18722	0.897950878750679	0.923404897039288	VEGFA	1
GO:2000756	regulation of peptidyl-lysine acetylation	1/665	63/18722	0.897950878750679	0.923404897039288	SPI1	1
GO:0045165	cell fate commitment	6/665	258/18722	0.899716491470559	0.925029160655498	KLF4/MCL1/PDPN/RHOA/IFRD1/NRP1	6
GO:0098659	inorganic cation import across plasma membrane	2/665	108/18722	0.90050668624458	0.925458691198421	WNK1/PRNP	2
GO:0099587	inorganic ion import across plasma membrane	2/665	108/18722	0.90050668624458	0.925458691198421	WNK1/PRNP	2
GO:0030104	water homeostasis	1/665	64/18722	0.90158787246046	0.9259953970094	PLEC	1
GO:0046530	photoreceptor cell differentiation	1/665	64/18722	0.90158787246046	0.9259953970094	VEGFA	1
GO:0055002	striated muscle cell development	1/665	64/18722	0.90158787246046	0.9259953970094	PLEC	1
GO:0033044	regulation of chromosome organization	4/665	187/18722	0.902854056814903	0.927104269084725	DUSP1/TERF2IP/HNRNPA1/RB1	4
GO:0072009	nephron epithelium development	2/665	109/18722	0.903346150730873	0.927417965117215	VEGFA/STAT1	2
GO:0048839	inner ear development	4/665	188/18722	0.9050474863794	0.928063606783812	MAFB/GABRB2/INSIG2/EPHB2	4
GO:0003170	heart valve development	1/665	65/18722	0.905095433014313	0.928063606783812	RB1	1
GO:0046513	ceramide biosynthetic process	1/665	65/18722	0.905095433014313	0.928063606783812	ST8SIA4	1
GO:0048645	animal organ formation	1/665	65/18722	0.905095433014313	0.928063606783812	CITED2	1
GO:0061512	protein localization to cilium	1/665	65/18722	0.905095433014313	0.928063606783812	SNX10	1
GO:1905330	regulation of morphogenesis of an epithelium	1/665	65/18722	0.905095433014313	0.928063606783812	VEGFA	1
GO:0030317	flagellated sperm motility	2/665	110/18722	0.906109827571958	0.92872052856932	UBE2B/VPS13A	2
GO:0097722	sperm motility	2/665	110/18722	0.906109827571958	0.92872052856932	UBE2B/VPS13A	2
GO:0006486	protein glycosylation	5/665	226/18722	0.907344062055509	0.929602141499872	ST8SIA4/B3GNT7/GCNT1/TMEM59/B3GNT5	5
GO:0043413	macromolecule glycosylation	5/665	226/18722	0.907344062055509	0.929602141499872	ST8SIA4/B3GNT7/GCNT1/TMEM59/B3GNT5	5
GO:0050909	sensory perception of taste	1/665	66/18722	0.908478159982501	0.930517831492659	CD36	1
GO:0071867	response to monoamine	2/665	111/18722	0.908799507860235	0.930517831492659	FLNA/LRRK2	2
GO:0071869	response to catecholamine	2/665	111/18722	0.908799507860235	0.930517831492659	FLNA/LRRK2	2
GO:0071826	ribonucleoprotein complex subunit organization	5/665	227/18722	0.909287497498863	0.93065016661905	RPS27L/SNRPB/PTGES3/SLU7/KIF5B	5
GO:0099111	microtubule-based transport	4/665	190/18722	0.909303261388754	0.93065016661905	BLOC1S1/BLOC1S2/DST/KIF5B	4
GO:0016573	histone acetylation	3/665	152/18722	0.910065956501973	0.931151094090327	SPI1/MORF4L1/PER1	3
GO:0042254	ribosome biogenesis	7/665	299/18722	0.910167407462939	0.931151094090327	GLUL/RPS27L/PTEN/NOP10/RPL26L1/RPP30/LSM6	7
GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	1/665	67/18722	0.911740489721547	0.931801405288112	ANXA1	1
GO:0009583	detection of light stimulus	1/665	67/18722	0.911740489721547	0.931801405288112	GNAQ	1
GO:0009880	embryonic pattern specification	1/665	67/18722	0.911740489721547	0.931801405288112	NRP1	1
GO:0042490	mechanoreceptor differentiation	1/665	67/18722	0.911740489721547	0.931801405288112	GABRB2	1
GO:0061371	determination of heart left/right asymmetry	1/665	67/18722	0.911740489721547	0.931801405288112	CITED2	1
GO:0001578	microtubule bundle formation	2/665	113/18722	0.91396388616714	0.933881684673249	UBE2B/MAPRE1	2
GO:1901607	alpha-amino acid biosynthetic process	1/665	68/18722	0.914886701157364	0.934615595057739	GLUL	1
GO:0060271	cilium assembly	8/665	337/18722	0.91505824658973	0.934615595057739	SNX10/DYNLL1/RAB8A/GSN/UBE2B/MAPRE1/FLNA/ATG3	8
GO:0003143	embryonic heart tube morphogenesis	1/665	69/18722	0.917920921363773	0.937154268524641	CITED2	1
GO:0070192	chromosome organization involved in meiotic cell cycle	1/665	69/18722	0.917920921363773	0.937154268524641	UBE2B	1
GO:0090630	activation of GTPase activity	2/665	115/18722	0.918852986294973	0.937913194061618	PTK2B/SIPA1L1	2
GO:1901605	alpha-amino acid metabolic process	4/665	195/18722	0.919210130440396	0.938085081784142	IL4I1/GLUL/DDAH2/KMO	4
GO:0070830	bicellular tight junction assembly	1/665	70/18722	0.920847130943631	0.939562767561045	RAB13	1
GO:0031123	RNA 3'-end processing	2/665	116/18722	0.921198451273144	0.939728305178064	SSB/LARP7	2
GO:0018393	internal peptidyl-lysine acetylation	3/665	158/18722	0.922872561427574	0.941242895607437	SPI1/MORF4L1/PER1	3
GO:0072078	nephron tubule morphogenesis	1/665	71/18722	0.923669169219553	0.941862078584566	VEGFA	1
GO:0042273	ribosomal large subunit biogenesis	1/665	72/18722	0.926390739240945	0.944443481851795	RPL26L1	1
GO:0006475	internal protein amino acid acetylation	3/665	160/18722	0.926756259642636	0.944622356526641	SPI1/MORF4L1/PER1	3
GO:0051298	centrosome duplication	1/665	73/18722	0.929015412613855	0.946536818509812	CHMP5	1
GO:0072089	stem cell proliferation	1/665	73/18722	0.929015412613855	0.946536818509812	EIF2AK2	1
GO:0000819	sister chromatid segregation	4/665	202/18722	0.931452471792429	0.948532426096004	DUSP1/RB1/CHMP5/RMDN1	4
GO:0070085	glycosylation	5/665	240/18722	0.931481618065004	0.948532426096004	ST8SIA4/B3GNT7/GCNT1/TMEM59/B3GNT5	5
GO:0120192	tight junction assembly	1/665	74/18722	0.931546634159879	0.948532426096004	RAB13	1
GO:0048285	organelle fission	12/665	488/18722	0.932622033566167	0.949432918235119	DUSP1/INF2/UBE2B/BNIP3/RALA/FLNA/RHOA/LRRK2/IGF2/RB1/CHMP5/RMDN1	12
GO:0071824	protein-DNA complex subunit organization	5/665	241/18722	0.93296976050891	0.949592404204236	ANP32E/PSMC6/RB1/RSF1/SETD2	5
GO:0031109	microtubule polymerization or depolymerization	2/665	122/18722	0.933983100045806	0.950044821993166	MAPRE1/RAC1	2
GO:0072329	monocarboxylic acid catabolic process	2/665	122/18722	0.933983100045806	0.950044821993166	HSD17B4/IRS2	2
GO:0061333	renal tubule morphogenesis	1/665	75/18722	0.933987726410183	0.950044821993166	VEGFA	1
GO:0009100	glycoprotein metabolic process	9/665	387/18722	0.935222899776399	0.95110657087962	SULF2/ST8SIA4/B3GNT7/CHST15/SOAT1/GCNT1/RNF5/TMEM59/B3GNT5	9
GO:0009101	glycoprotein biosynthetic process	7/665	317/18722	0.936448069797016	0.952157714175771	ST8SIA4/B3GNT7/CHST15/SOAT1/GCNT1/TMEM59/B3GNT5	7
GO:0006367	transcription initiation from RNA polymerase II promoter	1/665	77/18722	0.938612227552481	0.954162972169325	PSMC6	1
GO:0034728	nucleosome organization	3/665	167/18722	0.938978079833919	0.954339684411979	ANP32E/RSF1/SETD2	3
GO:0060294	cilium movement involved in cell motility	2/665	125/18722	0.939613958987703	0.954790712772211	UBE2B/VPS13A	2
GO:0006520	cellular amino acid metabolic process	6/665	284/18722	0.940794021736442	0.955411624497006	IL4I1/GLUL/SLC1A3/DDAH2/GATC/KMO	6
GO:0008306	associative learning	1/665	78/18722	0.940801708307515	0.955411624497006	FOS	1
GO:0035050	embryonic heart tube development	1/665	78/18722	0.940801708307515	0.955411624497006	CITED2	1
GO:0000245	spliceosomal complex assembly	1/665	79/18722	0.942913211417121	0.95736029841534	SLU7	1
GO:0001942	hair follicle development	1/665	81/18722	0.946913278682524	0.961028996334928	EGFR	1
GO:0008589	regulation of smoothened signaling pathway	1/665	81/18722	0.946913278682524	0.961028996334928	RB1	1
GO:0043583	ear development	4/665	213/18722	0.947332635756756	0.961258309455099	MAFB/GABRB2/INSIG2/EPHB2	4
GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	2/665	130/18722	0.947998428485012	0.961541263177655	CNIH4/LRRK2	2
GO:0007098	centrosome cycle	2/665	130/18722	0.947998428485012	0.961541263177655	ATF5/CHMP5	2
GO:0035082	axoneme assembly	1/665	82/18722	0.948807097129824	0.961968843887235	UBE2B	1
GO:2001252	positive regulation of chromosome organization	1/665	82/18722	0.948807097129824	0.961968843887235	HNRNPA1	1
GO:0007389	pattern specification process	10/665	436/18722	0.949462200156043	0.962436698914039	BHLHE40/MAFB/ABI1/CITED2/ITGAM/AIDA/ACVRL1/FBXL15/C1QA/NRP1	10
GO:0061053	somite development	1/665	83/18722	0.950633453374924	0.963427459884456	ABI1	1
GO:0006338	chromatin remodeling	5/665	255/18722	0.95096986155503	0.96357190865005	ANP32E/RB1/RSF1/JARID2/SETD2	5
GO:0140694	non-membrane-bounded organelle assembly	8/665	367/18722	0.951522974169101	0.963926843103303	RPS27L/GSN/MSN/MAPRE1/FLNA/RHOA/PLEC/CHMP5	8
GO:0022404	molting cycle process	1/665	84/18722	0.952394747087338	0.963926843103303	EGFR	1
GO:0022405	hair cycle process	1/665	84/18722	0.952394747087338	0.963926843103303	EGFR	1
GO:0032508	DNA duplex unwinding	1/665	84/18722	0.952394747087338	0.963926843103303	ANXA1	1
GO:0044782	cilium organization	8/665	368/18722	0.952452854893242	0.963926843103303	SNX10/DYNLL1/RAB8A/GSN/UBE2B/MAPRE1/FLNA/ATG3	8
GO:0009855	determination of bilateral symmetry	2/665	133/18722	0.952483848386383	0.963926843103303	CITED2/AIDA	2
GO:0009799	specification of symmetry	2/665	134/18722	0.953895109705969	0.964966150739621	CITED2/AIDA	2
GO:0097194	execution phase of apoptosis	1/665	85/18722	0.954093292703118	0.964966150739621	PLSCR1	1
GO:0098773	skin epidermis development	1/665	85/18722	0.954093292703118	0.964966150739621	EGFR	1
GO:0022618	ribonucleoprotein complex assembly	4/665	220/18722	0.955605351824196	0.966229591652925	RPS27L/SNRPB/PTGES3/SLU7	4
GO:0009798	axis specification	1/665	86/18722	0.955731322447843	0.966229591652925	CITED2	1
GO:0001539	cilium or flagellum-dependent cell motility	2/665	138/18722	0.95914961392112	0.969291090115488	UBE2B/VPS13A	2
GO:0060285	cilium-dependent cell motility	2/665	138/18722	0.95914961392112	0.969291090115488	UBE2B/VPS13A	2
GO:0006400	tRNA modification	1/665	90/18722	0.961720210290057	0.971099033958062	SSB	1
GO:0032392	DNA geometric change	1/665	90/18722	0.961720210290057	0.971099033958062	ANXA1	1
GO:0035278	miRNA mediated inhibition of translation	1/665	90/18722	0.961720210290057	0.971099033958062	ZFP36	1
GO:0040033	negative regulation of translation, ncRNA-mediated	1/665	90/18722	0.961720210290057	0.971099033958062	ZFP36	1
GO:0042147	retrograde transport, endosome to Golgi	1/665	91/18722	0.963086465128889	0.972083617321401	LRRK2	1
GO:0045974	regulation of translation, ncRNA-mediated	1/665	91/18722	0.963086465128889	0.972083617321401	ZFP36	1
GO:0007018	microtubule-based movement	8/665	382/18722	0.963900427466349	0.97270763949396	UBE2B/BLOC1S1/BLOC1S2/DST/DYNLT3/KIF5B/DYNLRB1/VPS13A	8
GO:0001708	cell fate specification	1/665	92/18722	0.964404027293522	0.973018273578726	NRP1	1
GO:0031023	microtubule organizing center organization	2/665	143/18722	0.96491419979572	0.973335411606399	ATF5/CHMP5	2
GO:0045132	meiotic chromosome segregation	1/665	93/18722	0.965674629647242	0.973904811149918	UBE2B	1
GO:0022613	ribonucleoprotein complex biogenesis	10/665	463/18722	0.969158246675513	0.977219818619862	GLUL/RPS27L/SNRPB/PTEN/NOP10/PTGES3/SLU7/RPL26L1/RPP30/LSM6	10
GO:0007281	germ cell development	5/665	278/18722	0.971245050230028	0.979125334613233	DYNLL1/UBE2B/ANG/PTK2B/HEXB	5
GO:0007631	feeding behavior	1/665	99/18722	0.972401638042983	0.979893783672673	FOS	1
GO:0021549	cerebellum development	1/665	99/18722	0.972401638042983	0.979893783672673	FCGR2B	1
GO:0098813	nuclear chromosome segregation	5/665	281/18722	0.97322358328009	0.980523253375643	DUSP1/UBE2B/RB1/CHMP5/RMDN1	5
GO:0065004	protein-DNA complex assembly	3/665	201/18722	0.975690213122478	0.98280915265884	PSMC6/RB1/RSF1	3
GO:0007030	Golgi organization	2/665	157/18722	0.977191008553254	0.984121441238028	LRRK2/PLK3	2
GO:0022037	metencephalon development	1/665	108/18722	0.9801057705034	0.986856904254842	FCGR2B	1
GO:0007286	spermatid development	2/665	165/18722	0.982217014973146	0.988782370754817	DYNLL1/UBE2B	2
GO:0022412	cellular process involved in reproduction in multicellular organism	7/665	384/18722	0.984505450153159	0.990885396367194	CD9/DYNLL1/UBE2B/ANG/PTK2B/KDM1B/HEXB	7
GO:0007059	chromosome segregation	6/665	346/18722	0.985105440883453	0.990912107827948	DUSP1/PLSCR1/UBE2B/RB1/CHMP5/RMDN1	6
GO:0030326	embryonic limb morphogenesis	1/665	116/18722	0.985130125709837	0.990912107827948	FBN2	1
GO:0035113	embryonic appendage morphogenesis	1/665	116/18722	0.985130125709837	0.990912107827948	FBN2	1
GO:0048515	spermatid differentiation	2/665	172/18722	0.985719268125186	0.991304079842609	DYNLL1/UBE2B	2
GO:0003341	cilium movement	2/665	175/18722	0.987005853809144	0.992397146152427	UBE2B/VPS13A	2
GO:0006364	rRNA processing	3/665	225/18722	0.987655607766003	0.992849589522054	NOP10/RPP30/LSM6	3
GO:0007368	determination of left/right symmetry	1/665	124/18722	0.988886979845765	0.993886408459747	CITED2	1
GO:0000280	nuclear division	8/665	439/18722	0.989091946020647	0.993891421698871	DUSP1/UBE2B/FLNA/RHOA/IGF2/RB1/CHMP5/RMDN1	8
GO:0006334	nucleosome assembly	1/665	129/18722	0.990736886899747	0.995141941772786	RSF1	1
GO:0007127	meiosis I	1/665	129/18722	0.990736886899747	0.995141941772786	UBE2B	1
GO:0016072	rRNA metabolic process	3/665	236/18722	0.991009767464079	0.995214900847943	NOP10/RPP30/LSM6	3
GO:0061982	meiosis I cell cycle process	1/665	135/18722	0.992555454076619	0.996565779143595	UBE2B	1
GO:0007224	smoothened signaling pathway	1/665	138/18722	0.993326293020936	0.996735650376348	RB1	1
GO:0035107	appendage morphogenesis	1/665	138/18722	0.993326293020936	0.996735650376348	FBN2	1
GO:0035108	limb morphogenesis	1/665	138/18722	0.993326293020936	0.996735650376348	FBN2	1
GO:0009952	anterior/posterior pattern specification	2/665	201/18722	0.994320177586742	0.997531546751334	BHLHE40/ABI1	2
GO:0006261	DNA-dependent DNA replication	1/665	151/18722	0.995845020348013	0.99865814187442	RRM2B	1
GO:0031497	chromatin assembly	1/665	151/18722	0.995845020348013	0.99865814187442	RSF1	1
GO:0007601	visual perception	2/665	215/18722	0.99638480879609	0.998997881726158	DHRS3/TGFBI	2
GO:0006325	chromatin organization	6/665	409/18722	0.9968144640569	0.999035972480598	ANP32E/RB1/ZNFX1/RSF1/JARID2/SETD2	6
GO:0050953	sensory perception of light stimulus	2/665	219/18722	0.996824826465047	0.999035972480598	DHRS3/TGFBI	2
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	1/665	167/18722	0.997682193031768	0.999555779761521	CADM1	1
GO:0048736	appendage development	1/665	172/18722	0.998068852386003	0.999555779761521	FBN2	1
GO:0060173	limb development	1/665	172/18722	0.998068852386003	0.999555779761521	FBN2	1
GO:0006333	chromatin assembly or disassembly	1/665	177/18722	0.998391089381289	0.999555779761521	RSF1	1
GO:0034470	ncRNA processing	5/665	395/18722	0.998578823324405	0.999555779761521	SSB/NOP10/LARP7/RPP30/LSM6	5
GO:0034660	ncRNA metabolic process	7/665	485/18722	0.998611460063867	0.999555779761521	SSB/ANG/NOP10/LARP7/GATC/RPP30/LSM6	7
GO:0140013	meiotic nuclear division	1/665	185/18722	0.998798751279645	0.999555779761521	UBE2B	1
GO:0051321	meiotic cell cycle	2/665	261/18722	0.999200511734105	0.999555779761521	DUSP1/UBE2B	2
GO:0006323	DNA packaging	1/665	199/18722	0.999279845877723	0.999555779761521	RSF1	1
GO:1903046	meiotic cell cycle process	1/665	202/18722	0.99935466189839	0.999555779761521	UBE2B	1
GO:0071103	DNA conformation change	2/665	290/18722	0.999696085850999	0.999696085850999	ANXA1/RSF1	2