ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0003735 structural constituent of ribosome 66/235 182/18367 6.50046547070613e-80 2.7561973595794e-77 RPS10/RPS3/RPL36A/RPL23A/RPL26/RPS8/RPS3A/RPS4X/RPL10/RPL9/RPL6/RPL41/RPL17/RPL5/RPS2/RPS18/RPS6/RPL7/RPL7A/RPS16/RPL15/RPL13/RPL10A/RPL31/RPS13/RPS19/RPL8/RPL29/RPS7/RPS27A/RPL27A/RPS5/RPSA/RPL14/RPLP1/RPL18A/RPL19/RPL30/RPLP0/RPS12/RPL23/RPL11/RPS15A/RPL24/RPL37/RPL3/RPS25/RPL32/RPS23/RPL18/RPL13A/RSL24D1/RPS24/RPL21/RPL28/RPL38/RPL27/RPS11/RPS20/RPS9/RPL22/RPS17/UBA52/MRPL16/MRPS12/RPL35A 66 GO:0019843 rRNA binding 18/235 68/18367 3.16496663151877e-19 6.70972925881978e-17 RPS3/RPL23A/RPS4X/RPL9/RPL5/RPS18/RPS13/RPL8/RPS5/RPL19/RPLP0/RPL23/RPL11/RPL37/NPM1/RPS11/RPS9/MRPL16 18 GO:0045296 cadherin binding 21/235 332/18367 1.94638033883656e-09 2.75088421222234e-07 LDHA/RPL23A/RPL6/RPS2/ALDOA/RPL7A/RPL15/PFN1/RPL29/S100P/RPL14/EIF3E/PRDX1/KRT18/ENO1/ANXA1/RPL24/RANBP1/RAN/EFHD2/EGFR 21 GO:0045182 translation regulator activity 14/235 140/18367 3.34395376496696e-09 3.54459099086498e-07 RPL10/EEF1B2/EIF3K/EIF3E/EIF5A/EIF3I/EIF3H/MCTS1/EIF1/EIF4A1/EIF2S2/RPS9/RPL22/EIF4B 14 GO:0008135 translation factor activity, RNA binding 11/235 84/18367 9.73016560010896e-09 8.25118042889239e-07 EEF1B2/EIF3K/EIF3E/EIF5A/EIF3I/EIF3H/MCTS1/EIF1/EIF4A1/EIF2S2/EIF4B 11 GO:0003743 translation initiation factor activity 9/235 51/18367 1.50324319563413e-08 1.06229185824812e-06 EIF3K/EIF3E/EIF3I/EIF3H/MCTS1/EIF1/EIF4A1/EIF2S2/EIF4B 9 GO:0004857 enzyme inhibitor activity 10/235 70/18367 1.96766149733313e-08 1.19184067838464e-06 RPL5/DYNLL1/RPS7/ANXA1/RPL23/RPL11/OAZ1/RPL37/RPS20/ANXA4 10 GO:0043021 ribonucleoprotein complex binding 13/235 149/18367 6.35339065666986e-08 3.36729704803503e-06 YBX3/RPSA/RPLP1/NME1/EIF3K/EIF5A/NEAT1/SNRPB/NPM1/SNRPD1/C1QBP/EIF1/EIF4B 13 GO:0090079 translation regulator activity, nucleic acid binding 11/235 108/18367 1.38072349823575e-07 6.50474181391063e-06 EEF1B2/EIF3K/EIF3E/EIF5A/EIF3I/EIF3H/MCTS1/EIF1/EIF4A1/EIF2S2/EIF4B 11 GO:0055106 ubiquitin-protein transferase regulator activity 6/235 22/18367 2.58716703962572e-07 1.0969588248013e-05 RPL5/RPS7/RPL23/RPL11/RPL37/RPS20 6 GO:0140678 molecular function inhibitor activity 11/235 128/18367 7.7839375913045e-07 3.00035412610283e-05 RPL5/DYNLL1/RPS7/CAV1/ANXA1/RPL23/RPL11/OAZ1/RPL37/RPS20/ANXA4 11 GO:0048027 mRNA 5'-UTR binding 6/235 27/18367 9.72869033015873e-07 3.43747058332275e-05 RPL26/RPS3A/RPL41/RPL5/RPS13/RPS7 6 GO:0043024 ribosomal small subunit binding 4/235 17/18367 5.45405214451399e-05 0.00177886008405687 NME1/NPM1/EIF1/EIF4B 4 GO:0016209 antioxidant activity 7/235 86/18367 0.000116927726837263 0.0035412397270714 GPX1/GPX3/PRDX1/GSTP1/GLRX/TXN/S100A9 7 GO:0048306 calcium-dependent protein binding 6/235 88/18367 0.000930605463433397 0.0263051144330507 S100P/ANXA1/S100A13/ANXA4/S100A10/S100A9 6 GO:0003697 single-stranded DNA binding 7/235 123/18367 0.00103759410772521 0.0274962438547181 NME1/ANXA1/YBX1/SUB1/SSBP1/POLR2G/HNRNPA1 7 GO:0097110 scaffold protein binding 5/235 67/18367 0.00166513512284737 0.0415304289463109 DYNLL1/KRT18/KRT8/DSP/IL6ST 5 GO:0005200 structural constituent of cytoskeleton 6/235 103/18367 0.00209581326645265 0.0493680458319959 KRT19/ACTG1/ARPC2/TUBA1C/TUBB6/DSP 6 GO:0019838 growth factor binding 7/235 141/18367 0.0022762611494794 0.0507965645989087 RPS2/RPS19/S100A13/EGFR/NRP1/FLT1/IL6ST 7 GO:0004602 glutathione peroxidase activity 3/235 22/18367 0.00266064939774986 0.056405767232297 GPX1/GPX3/GSTP1 3 GO:0017134 fibroblast growth factor binding 3/235 23/18367 0.00303109024948309 0.0611991555133729 RPS2/RPS19/S100A13 3 GO:0004601 peroxidase activity 4/235 51/18367 0.00407664206022921 0.0785680106153266 GPX1/GPX3/PRDX1/GSTP1 4 GO:0051082 unfolded protein binding 6/235 122/18367 0.00485214285919091 0.0894481987955194 NACA/NPM1/PTGES3/PFDN2/PFDN4/HSPE1 6 GO:0003727 single-stranded RNA binding 5/235 87/18367 0.00518667810471902 0.0906902702035837 ANXA1/SSB/POLR2G/HNRNPA1/EIF4B 5 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/235 55/18367 0.00534730366766414 0.0906902702035837 GPX1/GPX3/PRDX1/GSTP1 4 GO:0009055 electron transfer activity 6/235 126/18367 0.00566937846968029 0.0924544796594016 UQCRH/ETFB/NDUFC2/NDUFA13/CYCS/SDHB 6 GO:0008097 5S rRNA binding 2/235 10/18367 0.00685549366098451 0.096937364495291 RPL5/RPL11 2 GO:0030957 Tat protein binding 2/235 10/18367 0.00685549366098451 0.096937364495291 NPM1/SMARCB1 2 GO:0050786 RAGE receptor binding 2/235 10/18367 0.00685549366098451 0.096937364495291 S100A13/S100A9 2 GO:0098631 cell adhesion mediator activity 4/235 59/18367 0.00685877578976115 0.096937364495291 RPSA/KRT18/ANXA1/DSP 4 GO:0005507 copper ion binding 4/235 61/18367 0.00771042971546825 0.100137109989105 S100A13/CUTA/COA6/F5 4 GO:0008199 ferric iron binding 2/235 11/18367 0.00830865210531827 0.100137109989105 FTH1/FXN 2 GO:0047134 protein-disulfide reductase (NAD(P)) activity 2/235 11/18367 0.00830865210531827 0.100137109989105 GLRX/TXN 2 GO:0097371 MDM2/MDM4 family protein binding 2/235 11/18367 0.00830865210531827 0.100137109989105 RPL37/RPS20 2 GO:0097493 structural molecule activity conferring elasticity 2/235 11/18367 0.00830865210531827 0.100137109989105 FBN2/FBN1 2 GO:0031369 translation initiation factor binding 3/235 33/18367 0.00850220745190516 0.100137109989105 RPS24/POLR2G/EIF2S2 3 GO:0035198 miRNA binding 3/235 34/18367 0.00923827924716277 0.105865686508027 NEAT1/YBX1/HNRNPA1 3 GO:0043022 ribosome binding 4/235 66/18367 0.0101359302604771 0.113095642906376 RPSA/EIF3K/EIF5A/C1QBP 4 GO:0097718 disordered domain specific binding 3/235 36/18367 0.0108190720084117 0.11696985912993 FN1/GAPDH/CLTC 3 GO:0004859 phospholipase inhibitor activity 2/235 13/18367 0.0115866369892855 0.11696985912993 ANXA1/ANXA4 2 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/235 13/18367 0.0115866369892855 0.11696985912993 GLRX/TXN 2 GO:0031386 protein tag 2/235 13/18367 0.0115866369892855 0.11696985912993 RPS27A/UBA52 2 GO:0051087 chaperone binding 5/235 107/18367 0.0121652978425326 0.119955495005438 FN1/PTGES3/PFDN4/HSPE1/STIP1 5 GO:0140666 annealing activity 2/235 14/18367 0.013404710896438 0.129172668638402 ANXA1/EIF4B 2 GO:0031625 ubiquitin protein ligase binding 9/235 297/18367 0.0145458089067249 0.137053843921142 RPL5/RPS27A/TPI1/RPL23/ACTG1/RPL11/SLC25A5/EGFR/UBA52 9 GO:1990825 sequence-specific mRNA binding 2/235 15/18367 0.0153377798508593 0.141374318625312 SRSF3/SSB 2 GO:0016504 peptidase activator activity 3/235 43/18367 0.0175206220599947 0.158058377732718 FN1/CAV1/PSMD14 3 GO:0016835 carbon-oxygen lyase activity 4/235 79/18367 0.0185960041687022 0.161197055244989 RPS3/TPI1/ENO1/ECHS1 4 GO:0051879 Hsp90 protein binding 3/235 44/18367 0.0186289049693502 0.161197055244989 RPS3/PTGES3/STIP1 3 GO:0016722 oxidoreductase activity, acting on metal ions 2/235 17/18367 0.0195361085414889 0.165020247774706 FTH1/FXN 2 GO:0044389 ubiquitin-like protein ligase binding 9/235 316/18367 0.0208561576032292 0.165020247774706 RPL5/RPS27A/TPI1/RPL23/ACTG1/RPL11/SLC25A5/EGFR/UBA52 9 GO:0061980 regulatory RNA binding 3/235 46/18367 0.0209597478367889 0.165020247774706 NEAT1/YBX1/HNRNPA1 3 GO:1901681 sulfur compound binding 8/235 265/18367 0.0210772503473051 0.165020247774706 FN1/RPL29/PRMT1/GSTP1/ACBD6/RPL22/FBN1/NRP1 8 GO:0055102 lipase inhibitor activity 2/235 18/18367 0.0217951270645838 0.165020247774706 ANXA1/ANXA4 2 GO:0070122 isopeptidase activity 2/235 18/18367 0.0217951270645838 0.165020247774706 EIF3H/PSMD14 2 GO:0098641 cadherin binding involved in cell-cell adhesion 2/235 18/18367 0.0217951270645838 0.165020247774706 KRT18/ANXA1 2 GO:0003746 translation elongation factor activity 2/235 19/18367 0.0241566560857484 0.179691617199251 EEF1B2/EIF5A 2 GO:0098632 cell-cell adhesion mediator activity 3/235 49/18367 0.0247421751097846 0.180873831837046 KRT18/ANXA1/DSP 3 GO:0051117 ATPase binding 4/235 89/18367 0.0274049643510433 0.194011320783456 CAV1/SNU13/EGFR/ATP6V1E1 4 GO:0016860 intramolecular oxidoreductase activity 3/235 51/18367 0.0274544321863382 0.194011320783456 MIF/TPI1/PTGES3 3 GO:0051287 NAD binding 3/235 56/18367 0.0348981850781302 0.242570991362741 GAPDH/LDHA/HPGD 3 GO:0004536 deoxyribonuclease activity 3/235 57/18367 0.0364996513018013 0.249610518580061 RPS3/NME1/TATDN1 3 GO:0051537 2 iron, 2 sulfur cluster binding 2/235 24/18367 0.0374000613881468 0.251708349659909 SDHB/FXN 2 GO:0008327 methyl-CpG binding 2/235 25/18367 0.0403163137093793 0.267095578324638 ERH/PRMT1 2 GO:0008198 ferrous iron binding 2/235 26/18367 0.0433154875820257 0.282550257458137 FTH1/FXN 2 GO:0051059 NF-kappaB binding 2/235 29/18367 0.0527850025799592 0.334487910926941 NPM1/ANXA4 2 GO:0047485 protein N-terminus binding 4/235 110/18367 0.0528554010191157 0.334487910926941 EIF3E/EIF5A/NPM1/GLRX 4 GO:0051536 iron-sulfur cluster binding 3/235 68/18367 0.0565235291094108 0.347332990469423 RPS3/SDHB/FXN 3 GO:0051540 metal cluster binding 3/235 68/18367 0.0565235291094108 0.347332990469423 RPS3/SDHB/FXN 3 GO:0140142 nucleocytoplasmic carrier activity 2/235 31/18367 0.0594666977197184 0.360198283330866 NUTF2/RAN 2 GO:0008201 heparin binding 5/235 166/18367 0.0624385060459072 0.372872205119221 FN1/RPL29/RPL22/FBN1/NRP1 5 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 3/235 72/18367 0.0648578744098841 0.381940815969318 UQCRH/NDUFC2/NDUFA13 3 GO:0140104 molecular carrier activity 3/235 73/18367 0.0670251491454724 0.389296756680552 NUTF2/RAN/FXN 3 GO:0003725 double-stranded RNA binding 3/235 74/18367 0.0692252148085132 0.396641771335265 EIF4A1/CLTC/EIF4B 3 GO:0001618 virus receptor activity 3/235 76/18367 0.0737222909856972 0.413229153911849 RPSA/CD81/EGFR 3 GO:0140097 catalytic activity, acting on DNA 6/235 229/18367 0.0744954573981545 0.413229153911849 RPS3/NME1/ANXA1/PTGES3/TATDN1/RFC2 6 GO:0005539 glycosaminoglycan binding 6/235 230/18367 0.0757173617575056 0.413229153911849 FN1/RPL29/C1QBP/RPL22/FBN1/NRP1 6 GO:0140272 exogenous protein binding 3/235 77/18367 0.0760185707668024 0.413229153911849 RPSA/CD81/EGFR 3 GO:0042805 actinin binding 2/235 36/18367 0.0773254381494818 0.415012478169371 PDLIM2/CSRP2 2 GO:0019207 kinase regulator activity 6/235 233/18367 0.0794513112629786 0.41922998248291 RPLP1/CCNE1/NPM1/GSTP1/PKIB/CKS2 6 GO:0051020 GTPase binding 7/235 291/18367 0.0809367172472106 0.41922998248291 PFN1/YBX3/NUTF2/CAV1/ENO1/YBX1/RANBP1 7 GO:0015035 protein-disulfide reductase activity 2/235 37/18367 0.0810774966122609 0.41922998248291 GLRX/TXN 2 GO:0005504 fatty acid binding 2/235 39/18367 0.0887452163749615 0.453349057144381 GSTP1/S100A9 2 GO:0001046 core promoter sequence-specific DNA binding 2/235 42/18367 0.100626243107223 0.482160060832506 NPM1/SMARCB1 2 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/235 42/18367 0.100626243107223 0.482160060832506 NDUFC2/NDUFA13 2 GO:0008307 structural constituent of muscle 2/235 42/18367 0.100626243107223 0.482160060832506 KRT19/CSRP2 2 GO:0015036 disulfide oxidoreductase activity 2/235 42/18367 0.100626243107223 0.482160060832506 GLRX/TXN 2 GO:0019205 nucleobase-containing compound kinase activity 2/235 42/18367 0.100626243107223 0.482160060832506 NME1/N4BP2 2 GO:0008276 protein methyltransferase activity 3/235 88/18367 0.103259271061166 0.482160060832506 TRMT112/PRMT1/LCMT1 3 GO:0030544 Hsp70 protein binding 2/235 43/18367 0.104680175841234 0.482160060832506 RPS3/STIP1 2 GO:0050136 NADH dehydrogenase (quinone) activity 2/235 43/18367 0.104680175841234 0.482160060832506 NDUFC2/NDUFA13 2 GO:0016829 lyase activity 5/235 196/18367 0.107484146649655 0.482160060832506 RPS3/ALDOA/TPI1/ENO1/ECHS1 5 GO:0003954 NADH dehydrogenase activity 2/235 45/18367 0.112917510899681 0.482160060832506 NDUFC2/NDUFA13 2 GO:0003955 NAD(P)H dehydrogenase (quinone) activity 2/235 45/18367 0.112917510899681 0.482160060832506 NDUFC2/NDUFA13 2 GO:0005178 integrin binding 4/235 144/18367 0.113624542584117 0.482160060832506 FN1/CD81/FBN1/EGFR 4 GO:0043130 ubiquitin binding 3/235 92/18367 0.114000711430691 0.482160060832506 UCHL3/CKS2/N4BP2 3 GO:0004300 enoyl-CoA hydratase activity 1/235 10/18367 0.120853910595321 0.482160060832506 ECHS1 1 GO:0004955 prostaglandin receptor activity 1/235 10/18367 0.120853910595321 0.482160060832506 HPGD 1 GO:0005522 profilin binding 1/235 10/18367 0.120853910595321 0.482160060832506 ACTG1 1 GO:0032356 oxidized DNA binding 1/235 10/18367 0.120853910595321 0.482160060832506 RPS3 1 GO:0034511 U3 snoRNA binding 1/235 10/18367 0.120853910595321 0.482160060832506 SNU13 1 GO:0070567 cytidylyltransferase activity 1/235 10/18367 0.120853910595321 0.482160060832506 NANS 1 GO:0098505 G-rich strand telomeric DNA binding 1/235 10/18367 0.120853910595321 0.482160060832506 HNRNPA1 1 GO:0019887 protein kinase regulator activity 5/235 204/18367 0.121618560024 0.482160060832506 RPLP1/CCNE1/NPM1/PKIB/CKS2 5 GO:0046982 protein heterodimerization activity 7/235 328/18367 0.128952337948169 0.482160060832506 CAV1/TRMT112/RAN/LSM5/KRT10/SRI/LSM6 7 GO:0000774 adenyl-nucleotide exchange factor activity 1/235 11/18367 0.132108436444322 0.482160060832506 PFN1 1 GO:0004954 prostanoid receptor activity 1/235 11/18367 0.132108436444322 0.482160060832506 HPGD 1 GO:0005049 nuclear export signal receptor activity 1/235 11/18367 0.132108436444322 0.482160060832506 RAN 1 GO:0005347 ATP transmembrane transporter activity 1/235 11/18367 0.132108436444322 0.482160060832506 SLC25A5 1 GO:0008603 cAMP-dependent protein kinase regulator activity 1/235 11/18367 0.132108436444322 0.482160060832506 PKIB 1 GO:0016273 arginine N-methyltransferase activity 1/235 11/18367 0.132108436444322 0.482160060832506 PRMT1 1 GO:0016274 protein-arginine N-methyltransferase activity 1/235 11/18367 0.132108436444322 0.482160060832506 PRMT1 1 GO:0016832 aldehyde-lyase activity 1/235 11/18367 0.132108436444322 0.482160060832506 ALDOA 1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/235 11/18367 0.132108436444322 0.482160060832506 DSP 1 GO:0099186 structural constituent of postsynapse 1/235 11/18367 0.132108436444322 0.482160060832506 ACTG1 1 GO:1990459 transferrin receptor binding 1/235 11/18367 0.132108436444322 0.482160060832506 CD81 1 GO:0015485 cholesterol binding 2/235 50/18367 0.13418605466565 0.482160060832506 CAV1/CD81 2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/235 50/18367 0.13418605466565 0.482160060832506 CCNE1/CKS2 2 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/235 12/18367 0.14321949100063 0.485800513474136 RPS3 1 GO:0003964 RNA-directed DNA polymerase activity 1/235 12/18367 0.14321949100063 0.485800513474136 PTGES3 1 GO:0008296 3'-5'-exodeoxyribonuclease activity 1/235 12/18367 0.14321949100063 0.485800513474136 TATDN1 1 GO:0017154 semaphorin receptor activity 1/235 12/18367 0.14321949100063 0.485800513474136 NRP1 1 GO:0035325 Toll-like receptor binding 1/235 12/18367 0.14321949100063 0.485800513474136 S100A9 1 GO:0043047 single-stranded telomeric DNA binding 1/235 12/18367 0.14321949100063 0.485800513474136 HNRNPA1 1 GO:0061578 Lys63-specific deubiquitinase activity 1/235 12/18367 0.14321949100063 0.485800513474136 PSMD14 1 GO:0017069 snRNA binding 2/235 53/18367 0.147345550187925 0.491549561599006 EIF5A/SNU13 2 GO:0005544 calcium-dependent phospholipid binding 2/235 54/18367 0.151789319628074 0.491549561599006 ANXA1/ANXA4 2 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/235 13/18367 0.154188895501575 0.491549561599006 PPP1R14B 1 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/235 13/18367 0.154188895501575 0.491549561599006 PTPMT1 1 GO:0060590 ATPase regulator activity 1/235 13/18367 0.154188895501575 0.491549561599006 PFN1 1 GO:0061133 endopeptidase activator activity 1/235 13/18367 0.154188895501575 0.491549561599006 PSMD14 1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/235 13/18367 0.154188895501575 0.491549561599006 CKS2 1 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/235 13/18367 0.154188895501575 0.491549561599006 PTPMT1 1 GO:0005080 protein kinase C binding 2/235 55/18367 0.156259328024838 0.494432500615906 C1QBP/DSP 2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/235 14/18367 0.165018448163509 0.500006764939189 MIF 1 GO:0036041 long-chain fatty acid binding 1/235 14/18367 0.165018448163509 0.500006764939189 S100A9 1 GO:0043023 ribosomal large subunit binding 1/235 14/18367 0.165018448163509 0.500006764939189 NPM1 1 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/235 57/18367 0.165272531857166 0.500006764939189 NDUFC2/NDUFA13 2 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/235 57/18367 0.165272531857166 0.500006764939189 GLRX/TXN 2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/235 58/18367 0.169813039311717 0.500006764939189 GSTP1/NANS 2 GO:0032182 ubiquitin-like protein binding 3/235 111/18367 0.170049712581626 0.500006764939189 UCHL3/CKS2/N4BP2 3 GO:0061134 peptidase regulator activity 5/235 230/18367 0.172970087389758 0.500006764939189 FN1/GAPDH/CAV1/SERPINB1/PSMD14 5 GO:0001846 opsonin binding 1/235 15/18367 0.175709924471555 0.500006764939189 C1QBP 1 GO:0004953 icosanoid receptor activity 1/235 15/18367 0.175709924471555 0.500006764939189 HPGD 1 GO:0019215 intermediate filament binding 1/235 15/18367 0.175709924471555 0.500006764939189 NME1 1 GO:0030280 structural constituent of skin epidermis 1/235 15/18367 0.175709924471555 0.500006764939189 KRT10 1 GO:0050998 nitric-oxide synthase binding 1/235 15/18367 0.175709924471555 0.500006764939189 CAV1 1 GO:0051371 muscle alpha-actinin binding 1/235 15/18367 0.175709924471555 0.500006764939189 PDLIM2 1 GO:0098847 sequence-specific single stranded DNA binding 1/235 15/18367 0.175709924471555 0.500006764939189 HNRNPA1 1 GO:0032934 sterol binding 2/235 60/18367 0.178955370333361 0.50412254000239 CAV1/CD81 2 GO:0101005 deubiquitinase activity 3/235 114/18367 0.179534206463115 0.50412254000239 EIF3H/PSMD14/UCHL3 3 GO:0005092 GDP-dissociation inhibitor activity 1/235 16/18367 0.186265077465735 0.512833719775789 RANBP1 1 GO:0017070 U6 snRNA binding 1/235 16/18367 0.186265077465735 0.512833719775789 EIF5A 1 GO:0070403 NAD+ binding 1/235 16/18367 0.186265077465735 0.512833719775789 HPGD 1 GO:0000400 four-way junction DNA binding 1/235 17/18367 0.1966856380235 0.519270329105454 HMGB3 1 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/235 17/18367 0.1966856380235 0.519270329105454 ATP6V1E1 1 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/235 17/18367 0.1966856380235 0.519270329105454 ATP6V1E1 1 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/235 17/18367 0.1966856380235 0.519270329105454 ATP6V1E1 1 GO:0070064 proline-rich region binding 1/235 17/18367 0.1966856380235 0.519270329105454 PFN1 1 GO:0070628 proteasome binding 1/235 17/18367 0.1966856380235 0.519270329105454 PSMD14 1 GO:0016836 hydro-lyase activity 2/235 64/18367 0.197450747219283 0.519270329105454 ENO1/ECHS1 2 GO:0015399 primary active transmembrane transporter activity 4/235 181/18367 0.202263667489797 0.519270329105454 UQCRH/NDUFC2/NDUFA13/ATP6V1E1 4 GO:0000295 adenine nucleotide transmembrane transporter activity 1/235 18/18367 0.206973315138731 0.519270329105454 SLC25A5 1 GO:0004550 nucleoside diphosphate kinase activity 1/235 18/18367 0.206973315138731 0.519270329105454 NME1 1 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/235 18/18367 0.206973315138731 0.519270329105454 SLC25A5 1 GO:0008301 DNA binding, bending 1/235 18/18367 0.206973315138731 0.519270329105454 HMGB3 1 GO:0048038 quinone binding 1/235 18/18367 0.206973315138731 0.519270329105454 SDHB 1 GO:0098918 structural constituent of synapse 1/235 18/18367 0.206973315138731 0.519270329105454 ACTG1 1 GO:1904047 S-adenosyl-L-methionine binding 1/235 18/18367 0.206973315138731 0.519270329105454 PRMT1 1 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/235 124/18367 0.212101871549278 0.523328151194005 EGFR/NRP1/FLT1 3 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/235 124/18367 0.212101871549278 0.523328151194005 LDHA/MDH2/HPGD 3 GO:0019783 ubiquitin-like protein-specific protease activity 3/235 125/18367 0.215428599641062 0.523328151194005 EIF3H/PSMD14/UCHL3 3 GO:0000339 RNA cap binding 1/235 19/18367 0.217129796197229 0.523328151194005 EIF4A1 1 GO:0004860 protein kinase inhibitor activity 2/235 70/18367 0.225583208384558 0.523328151194005 NPM1/PKIB 2 GO:0009678 pyrophosphate hydrolysis-driven proton transmembrane transporter activity 1/235 20/18367 0.227156747248769 0.523328151194005 ATP6V1E1 1 GO:0031690 adrenergic receptor binding 1/235 20/18367 0.227156747248769 0.523328151194005 C1QBP 1 GO:0061608 nuclear import signal receptor activity 1/235 20/18367 0.227156747248769 0.523328151194005 NUTF2 1 GO:0031072 heat shock protein binding 3/235 129/18367 0.228842513230743 0.523328151194005 RPS3/PTGES3/STIP1 3 GO:0015078 proton transmembrane transporter activity 3/235 130/18367 0.232220776013114 0.523328151194005 UQCRH/SLC25A5/ATP6V1E1 3 GO:0000049 tRNA binding 2/235 72/18367 0.235030798390954 0.523328151194005 SSB/RPL35A 2 GO:0003678 DNA helicase activity 2/235 72/18367 0.235030798390954 0.523328151194005 ANXA1/RFC2 2 GO:0001848 complement binding 1/235 21/18367 0.237055813275724 0.523328151194005 C1QBP 1 GO:0015216 purine nucleotide transmembrane transporter activity 1/235 21/18367 0.237055813275724 0.523328151194005 SLC25A5 1 GO:0051010 microtubule plus-end binding 1/235 21/18367 0.237055813275724 0.523328151194005 CLIP1 1 GO:1990381 ubiquitin-specific protease binding 1/235 21/18367 0.237055813275724 0.523328151194005 CLTC 1 GO:0031267 small GTPase binding 5/235 259/18367 0.238202118128837 0.523328151194005 PFN1/YBX3/NUTF2/CAV1/RANBP1 5 GO:0016779 nucleotidyltransferase activity 3/235 132/18367 0.239004331775507 0.523328151194005 PTGES3/POLR2G/NANS 3 GO:0033293 monocarboxylic acid binding 2/235 73/18367 0.239763351890826 0.523328151194005 GSTP1/S100A9 2 GO:0106306 protein serine phosphatase activity 2/235 73/18367 0.239763351890826 0.523328151194005 PPP4C/PTPMT1 2 GO:0106307 protein threonine phosphatase activity 2/235 73/18367 0.239763351890826 0.523328151194005 PPP4C/PTPMT1 2 GO:0140297 DNA-binding transcription factor binding 7/235 394/18367 0.24136325561948 0.523328151194005 RPS3/PTMA/NPM1/SRI/ISL1/ANXA4/SMARCB1 7 GO:0044325 transmembrane transporter binding 3/235 133/18367 0.242408862342539 0.523328151194005 CAV1/SRI/S100A10 3 GO:0019210 kinase inhibitor activity 2/235 74/18367 0.244500522365335 0.523328151194005 NPM1/PKIB 2 GO:0000062 fatty-acyl-CoA binding 1/235 22/18367 0.246828618458337 0.523328151194005 ACBD6 1 GO:0005540 hyaluronic acid binding 1/235 22/18367 0.246828618458337 0.523328151194005 C1QBP 1 GO:0008320 protein transmembrane transporter activity 1/235 22/18367 0.246828618458337 0.523328151194005 TOMM22 1 GO:0070034 telomerase RNA binding 1/235 22/18367 0.246828618458337 0.523328151194005 SNRPB 1 GO:0070182 DNA polymerase binding 1/235 22/18367 0.246828618458337 0.523328151194005 PTGES3 1 GO:0002020 protease binding 3/235 135/18367 0.249241546403124 0.523328151194005 FN1/SRI/CLTC 3 GO:0004713 protein tyrosine kinase activity 3/235 136/18367 0.252668956545346 0.523328151194005 EGFR/NRP1/FLT1 3 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 3/235 136/18367 0.252668956545346 0.523328151194005 LDHA/MDH2/HPGD 3 GO:0004529 exodeoxyribonuclease activity 1/235 23/18367 0.256476766436657 0.523328151194005 TATDN1 1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/235 23/18367 0.256476766436657 0.523328151194005 ETHE1 1 GO:0016895 exodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/235 23/18367 0.256476766436657 0.523328151194005 TATDN1 1 GO:0017116 single-stranded DNA helicase activity 1/235 23/18367 0.256476766436657 0.523328151194005 RFC2 1 GO:0050750 low-density lipoprotein particle receptor binding 1/235 23/18367 0.256476766436657 0.523328151194005 CLTC 1 GO:1901567 fatty acid derivative binding 1/235 23/18367 0.256476766436657 0.523328151194005 ACBD6 1 GO:0003730 mRNA 3'-UTR binding 4/235 201/18367 0.256727017566871 0.523328151194005 RPL41/RPL5/YBX3/RPS7 4 GO:0008171 O-methyltransferase activity 1/235 24/18367 0.266001840569201 0.532003681138402 LCMT1 1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/235 24/18367 0.266001840569201 0.532003681138402 ETHE1 1 GO:0016769 transferase activity, transferring nitrogenous groups 1/235 24/18367 0.266001840569201 0.532003681138402 GAPDH 1 GO:0043274 phospholipase binding 1/235 24/18367 0.266001840569201 0.532003681138402 SRSF3 1 GO:0008266 poly(U) RNA binding 1/235 25/18367 0.27540540418836 0.543125076166813 SSB 1 GO:0051019 mitogen-activated protein kinase binding 1/235 25/18367 0.27540540418836 0.543125076166813 PRMT1 1 GO:0120227 acyl-CoA binding 1/235 25/18367 0.27540540418836 0.543125076166813 ACBD6 1 GO:0019199 transmembrane receptor protein kinase activity 3/235 143/18367 0.276833592919871 0.543414089805673 EGFR/NRP1/FLT1 3 GO:0004518 nuclease activity 4/235 210/18367 0.282151081501014 0.548872958363538 RPS3/NME1/TATDN1/N4BP2 4 GO:0004364 glutathione transferase activity 1/235 26/18367 0.284689000852613 0.548872958363538 GSTP1 1 GO:0001540 amyloid-beta binding 2/235 84/18367 0.291941129984126 0.548872958363538 PFDN2/PFDN4 2 GO:0004709 MAP kinase kinase kinase activity 1/235 27/18367 0.293854154595574 0.548872958363538 EGFR 1 GO:0015215 nucleotide transmembrane transporter activity 1/235 27/18367 0.293854154595574 0.548872958363538 SLC25A5 1 GO:0022884 macromolecule transmembrane transporter activity 1/235 27/18367 0.293854154595574 0.548872958363538 TOMM22 1 GO:0023026 MHC class II protein complex binding 1/235 27/18367 0.293854154595574 0.548872958363538 CD81 1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/235 27/18367 0.293854154595574 0.548872958363538 PTPMT1 1 GO:0043425 bHLH transcription factor binding 1/235 27/18367 0.293854154595574 0.548872958363538 ISL1 1 GO:0051393 alpha-actinin binding 1/235 27/18367 0.293854154595574 0.548872958363538 PDLIM2 1 GO:0051959 dynein light intermediate chain binding 1/235 27/18367 0.293854154595574 0.548872958363538 DYNLL1 1 GO:0003785 actin monomer binding 1/235 28/18367 0.302902370171912 0.551204313102535 PFN1 1 GO:0008187 poly-pyrimidine tract binding 1/235 28/18367 0.302902370171912 0.551204313102535 SSB 1 GO:0017056 structural constituent of nuclear pore 1/235 28/18367 0.302902370171912 0.551204313102535 NUTF2 1 GO:0043236 laminin binding 1/235 28/18367 0.302902370171912 0.551204313102535 RPSA 1 GO:0051861 glycolipid binding 1/235 28/18367 0.302902370171912 0.551204313102535 MANF 1 GO:0070325 lipoprotein particle receptor binding 1/235 28/18367 0.302902370171912 0.551204313102535 CLTC 1 GO:0005506 iron ion binding 3/235 151/18367 0.30470945865291 0.552123121661684 FTH1/ETHE1/FXN 3 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/235 88/18367 0.31084598715374 0.560246171691877 NDUFC2/NDUFA13 2 GO:0015301 anion:anion antiporter activity 1/235 29/18367 0.311835133300196 0.560246171691877 SLC25A5 1 GO:0000287 magnesium ion binding 4/235 221/18367 0.313708239212419 0.561233305595214 S100P/NME1/ENO1/RAN 4 GO:0043178 alcohol binding 2/235 89/18367 0.315557266133646 0.562169247229689 CAV1/CD81 2 GO:0004386 helicase activity 3/235 156/18367 0.322201071225476 0.571603574056911 ANXA1/EIF4A1/RFC2 3 GO:0016853 isomerase activity 3/235 158/18367 0.329201821225837 0.577060761029165 MIF/TPI1/PTGES3 3 GO:0043015 gamma-tubulin binding 1/235 31/18367 0.329360151342118 0.577060761029165 NME1 1 GO:0140318 protein transporter activity 1/235 31/18367 0.329360151342118 0.577060761029165 TOMM22 1 GO:0001223 transcription coactivator binding 1/235 32/18367 0.337955284655523 0.584869553852824 RPL23 1 GO:0015605 organophosphate ester transmembrane transporter activity 1/235 32/18367 0.337955284655523 0.584869553852824 SLC25A5 1 GO:0030515 snoRNA binding 1/235 32/18367 0.337955284655523 0.584869553852824 SNU13 1 GO:0008200 ion channel inhibitor activity 1/235 33/18367 0.346440722785109 0.59230188089067 CAV1 1 GO:0051427 hormone receptor binding 1/235 33/18367 0.346440722785109 0.59230188089067 CSH1 1 GO:0140323 solute:anion antiporter activity 1/235 33/18367 0.346440722785109 0.59230188089067 SLC25A5 1 GO:0015631 tubulin binding 6/235 375/18367 0.348017036088346 0.592607322495818 GAPDH/RPS3/ALDOA/NME1/S100A9/CLIP1 6 GO:0016248 channel inhibitor activity 1/235 34/18367 0.354817859806244 0.594635464655524 CAV1 1 GO:0030291 protein serine/threonine kinase inhibitor activity 1/235 34/18367 0.354817859806244 0.594635464655524 PKIB 1 GO:0045505 dynein intermediate chain binding 1/235 34/18367 0.354817859806244 0.594635464655524 DYNLL1 1 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/235 34/18367 0.354817859806244 0.594635464655524 PTPMT1 1 GO:0004722 protein serine/threonine phosphatase activity 2/235 98/18367 0.357567717554913 0.596884693871194 PPP4C/PTPMT1 2 GO:0005496 steroid binding 2/235 100/18367 0.366784897512353 0.60330569052263 CAV1/CD81 2 GO:0000217 DNA secondary structure binding 1/235 36/18367 0.371252718838392 0.60330569052263 HMGB3 1 GO:0023023 MHC protein complex binding 1/235 36/18367 0.371252718838392 0.60330569052263 CD81 1 GO:0034061 DNA polymerase activity 1/235 36/18367 0.371252718838392 0.60330569052263 PTGES3 1 GO:0042162 telomeric DNA binding 1/235 36/18367 0.371252718838392 0.60330569052263 HNRNPA1 1 GO:0043394 proteoglycan binding 1/235 36/18367 0.371252718838392 0.60330569052263 FN1 1 GO:0030295 protein kinase activator activity 2/235 101/18367 0.371374493458505 0.60330569052263 RPLP1/CKS2 2 GO:0005201 extracellular matrix structural constituent 3/235 172/18367 0.378051761374096 0.609199894210132 FN1/FBN2/FBN1 3 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/235 37/18367 0.379313141678006 0.609199894210132 GAPDH 1 GO:0042056 chemoattractant activity 1/235 37/18367 0.379313141678006 0.609199894210132 MIF 1 GO:0004520 endodeoxyribonuclease activity 1/235 38/18367 0.387270665502648 0.61730361719219 RPS3 1 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/235 38/18367 0.387270665502648 0.61730361719219 RPS3 1 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/235 39/18367 0.395126598374428 0.625125663099842 POLR2G 1 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/235 39/18367 0.395126598374428 0.625125663099842 NME1 1 GO:0019209 kinase activator activity 2/235 107/18367 0.398620155822157 0.628022302508204 RPLP1/CKS2 2 GO:0031492 nucleosomal DNA binding 1/235 40/18367 0.402882231797716 0.628022302508204 SMARCB1 1 GO:0042287 MHC protein binding 1/235 40/18367 0.402882231797716 0.628022302508204 CD81 1 GO:0044183 protein folding chaperone 1/235 40/18367 0.402882231797716 0.628022302508204 PFDN2 1 GO:0030331 estrogen receptor binding 1/235 41/18367 0.410538840927826 0.637613437924536 ISL1 1 GO:0008094 ATP-dependent activity, acting on DNA 2/235 111/18367 0.416478582961594 0.644477807210642 ANXA1/RFC2 2 GO:0051539 4 iron, 4 sulfur cluster binding 1/235 42/18367 0.41809768477711 0.644630612165434 SDHB 1 GO:0004843 thiol-dependent deubiquitinase 2/235 113/18367 0.425308146986603 0.646729185381429 PSMD14/UCHL3 2 GO:0005246 calcium channel regulator activity 1/235 43/18367 0.42556000641844 0.646729185381429 SRI 1 GO:0034062 5'-3' RNA polymerase activity 1/235 43/18367 0.42556000641844 0.646729185381429 POLR2G 1 GO:0097747 RNA polymerase activity 1/235 43/18367 0.42556000641844 0.646729185381429 POLR2G 1 GO:0003713 transcription coactivator activity 4/235 262/18367 0.432201610093357 0.650925752024578 SUB1/NPM1/VGLL1/SMARCB1 4 GO:0001784 phosphotyrosine residue binding 1/235 44/18367 0.432927033186158 0.650925752024578 PFN1 1 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/235 44/18367 0.432927033186158 0.650925752024578 GAPDH 1 GO:0008234 cysteine-type peptidase activity 3/235 190/18367 0.43965539642823 0.658706318323567 EIF3H/PSMD14/UCHL3 3 GO:0004864 protein phosphatase inhibitor activity 1/235 46/18367 0.44738003393346 0.66791948728094 PPP1R14B 1 GO:0061135 endopeptidase regulator activity 3/235 194/18367 0.453048951112772 0.669078456669622 GAPDH/SERPINB1/PSMD14 3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/235 47/18367 0.454468385662385 0.669078456669622 PTPMT1 1 GO:0019829 ATPase-coupled cation transmembrane transporter activity 1/235 47/18367 0.454468385662385 0.669078456669622 ATP6V1E1 1 GO:0035254 glutamate receptor binding 1/235 47/18367 0.454468385662385 0.669078456669622 MYL12A 1 GO:0008017 microtubule binding 4/235 271/18367 0.457695980089969 0.671498600547222 GAPDH/RPS3/S100A9/CLIP1 4 GO:0015026 coreceptor activity 1/235 48/18367 0.461466198400886 0.674695407317157 NRP1 1 GO:0005179 hormone activity 2/235 122/18367 0.464149823662419 0.676287028291634 FBN1/CSH1 2 GO:0019212 phosphatase inhibitor activity 1/235 49/18367 0.46837462371754 0.677784438417191 PPP1R14B 1 GO:0043539 protein serine/threonine kinase activator activity 1/235 49/18367 0.46837462371754 0.677784438417191 CKS2 1 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/235 50/18367 0.47519479859615 0.685314947635264 SLC25A5 1 GO:0008242 omega peptidase activity 2/235 126/18367 0.48091409602955 0.690329076157913 PSMD14/UCHL3 2 GO:0051018 protein kinase A binding 1/235 51/18367 0.481927845619675 0.690329076157913 RPS3 1 GO:0016830 carbon-carbon lyase activity 1/235 52/18367 0.488574873151853 0.697468696408687 ALDOA 1 GO:0004519 endonuclease activity 2/235 129/18367 0.493274945097168 0.697468696408687 RPS3/N4BP2 2 GO:0003779 actin binding 6/235 440/18367 0.495123925020794 0.697468696408687 ALDOA/PFN1/PDLIM2/CFL1/ARPC2/EGFR 6 GO:0050661 NADP binding 1/235 53/18367 0.495136975516544 0.697468696408687 GAPDH 1 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/235 53/18367 0.495136975516544 0.697468696408687 SLC25A5 1 GO:0008408 3'-5' exonuclease activity 1/235 54/18367 0.501615233174817 0.701930227280933 TATDN1 1 GO:0015459 potassium channel regulator activity 1/235 54/18367 0.501615233174817 0.701930227280933 CAV1 1 GO:0042054 histone methyltransferase activity 1/235 56/18367 0.514324467949432 0.712658739903787 PRMT1 1 GO:0045309 protein phosphorylated amino acid binding 1/235 56/18367 0.514324467949432 0.712658739903787 PFN1 1 GO:0050840 extracellular matrix binding 1/235 56/18367 0.514324467949432 0.712658739903787 RPSA 1 GO:0008168 methyltransferase activity 3/235 214/18367 0.517843675720675 0.715197780148424 TRMT112/PRMT1/LCMT1 3 GO:0051015 actin filament binding 3/235 217/18367 0.527209675685772 0.721326320643627 CFL1/ARPC2/EGFR 3 GO:0005525 GTP binding 5/235 377/18367 0.530525507466435 0.721326320643627 ARF5/NME1/RAN/TUBA1C/TUBB6 5 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/235 59/18367 0.532785718461541 0.721326320643627 TATDN1 1 GO:0036002 pre-mRNA binding 1/235 59/18367 0.532785718461541 0.721326320643627 HNRNPA1 1 GO:0019955 cytokine binding 2/235 139/18367 0.533109486094578 0.721326320643627 NRP1/IL6ST 2 GO:0099106 ion channel regulator activity 2/235 139/18367 0.533109486094578 0.721326320643627 CAV1/SRI 2 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 4/235 299/18367 0.534189775193629 0.721326320643627 NPM1/ISL1/ANXA4/SMARCB1 4 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/235 60/18367 0.538782843006087 0.725218810903431 SDHB 1 GO:0043621 protein self-association 1/235 61/18367 0.544703312328945 0.730867735529977 MDH2 1 GO:1990841 promoter-specific chromatin binding 1/235 62/18367 0.550548102102937 0.735582033451203 ISL1 1 GO:0016741 transferase activity, transferring one-carbon groups 3/235 225/18367 0.551686525088402 0.735582033451203 TRMT112/PRMT1/LCMT1 3 GO:0016247 channel regulator activity 2/235 145/18367 0.55596709352663 0.738965666631006 CAV1/SRI 2 GO:0002039 p53 binding 1/235 66/18367 0.573189549626945 0.759476153255703 SMARCB1 1 GO:0019001 guanyl nucleotide binding 5/235 398/18367 0.578809988273697 0.762159736111949 ARF5/NME1/RAN/TUBA1C/TUBB6 5 GO:0032561 guanyl ribonucleotide binding 5/235 398/18367 0.578809988273697 0.762159736111949 ARF5/NME1/RAN/TUBA1C/TUBB6 5 GO:0003684 damaged DNA binding 1/235 68/18367 0.584080669306549 0.764352480820916 RPS3 1 GO:0008080 N-acetyltransferase activity 1/235 68/18367 0.584080669306549 0.764352480820916 SAT1 1 GO:0005518 collagen binding 1/235 69/18367 0.589422001768048 0.768969011537392 FN1 1 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/235 156/18367 0.595786368637216 0.77312419956687 PRMT1/LCMT1 2 GO:0022804 active transmembrane transporter activity 5/235 406/18367 0.596505467505609 0.77312419956687 UQCRH/SLC25A5/NDUFC2/NDUFA13/ATP6V1E1 5 GO:0031491 nucleosome binding 1/235 71/18367 0.599900617116746 0.77312419956687 SMARCB1 1 GO:0048029 monosaccharide binding 1/235 71/18367 0.599900617116746 0.77312419956687 ALDOA 1 GO:0030276 clathrin binding 1/235 72/18367 0.605039628648095 0.776840462325414 CLTC 1 GO:0042393 histone binding 3/235 244/18367 0.606714796615803 0.776840462325414 NPM1/MORC4/CKS2 3 GO:0035064 methylated histone binding 1/235 73/18367 0.610112910269724 0.776840462325414 MORC4 1 GO:0140034 methylation-dependent protein binding 1/235 73/18367 0.610112910269724 0.776840462325414 MORC4 1 GO:0005254 chloride channel activity 1/235 74/18367 0.615121299145126 0.780107146999841 CLIC3 1 GO:0008083 growth factor activity 2/235 162/18367 0.616358241143742 0.780107146999841 MANF/CSH1 2 GO:0019003 GDP binding 1/235 75/18367 0.620065621820515 0.782463760868745 RAN 1 GO:0003924 GTPase activity 4/235 337/18367 0.628648460543677 0.790001469610463 ARF5/RAN/TUBA1C/TUBB6 4 GO:0003724 RNA helicase activity 1/235 77/18367 0.629765322472492 0.790001469610463 EIF4A1 1 GO:0001221 transcription coregulator binding 1/235 78/18367 0.634522301653408 0.79362081386739 RPL23 1 GO:0008186 ATP-dependent activity, acting on RNA 1/235 79/18367 0.639218417302785 0.797142967459944 EIF4A1 1 GO:0004527 exonuclease activity 1/235 80/18367 0.643854444858223 0.800569749618435 TATDN1 1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/235 82/18367 0.652949288373597 0.809504380907618 PFN1 1 GO:0004721 phosphoprotein phosphatase activity 2/235 174/18367 0.655080851258841 0.809779244704806 PPP4C/PTPMT1 2 GO:0031406 carboxylic acid binding 2/235 176/18367 0.661223913236739 0.81499691631505 GSTP1/S100A9 2 GO:0022853 active ion transmembrane transporter activity 3/235 267/18367 0.6670975839128 0.819853262547905 UQCRH/SLC25A5/ATP6V1E1 3 GO:0042562 hormone binding 1/235 86/18367 0.670450960705125 0.821593084794719 EGFR 1 GO:0004866 endopeptidase inhibitor activity 2/235 180/18367 0.673247279169158 0.822032769347093 GAPDH/SERPINB1 2 GO:0005253 anion channel activity 1/235 87/18367 0.67468727295469 0.822032769347093 CLIC3 1 GO:0005126 cytokine receptor binding 3/235 271/18367 0.676883118659611 0.822345106910244 MIF/CSH1/IL6ST 3 GO:0051219 phosphoprotein binding 1/235 88/18367 0.678869356699528 0.822401734973143 PFN1 1 GO:0015297 antiporter activity 1/235 89/18367 0.682997903183231 0.822702019743438 SLC25A5 1 GO:0019888 protein phosphatase regulator activity 1/235 89/18367 0.682997903183231 0.822702019743438 PPP1R14B 1 GO:0016791 phosphatase activity 3/235 275/18367 0.68645589415852 0.824524926694653 PPP4C/HDDC2/PTPMT1 3 GO:0016407 acetyltransferase activity 1/235 91/18367 0.691097105583215 0.827754725331308 SAT1 1 GO:0030414 peptidase inhibitor activity 2/235 187/18367 0.693455697961854 0.827835108531628 GAPDH/SERPINB1 2 GO:0051213 dioxygenase activity 1/235 92/18367 0.695069100559574 0.827835108531628 ETHE1 1 GO:0008022 protein C-terminus binding 2/235 189/18367 0.699037664868669 0.830120147013103 FN1/STIP1 2 GO:0008237 metallopeptidase activity 2/235 190/18367 0.701797050703142 0.830120147013103 EIF3H/PSMD14 2 GO:0016410 N-acyltransferase activity 1/235 94/18367 0.702861162211566 0.830120147013103 SAT1 1 GO:0004896 cytokine receptor activity 1/235 97/18367 0.714179038103695 0.838814161096861 IL6ST 1 GO:0008170 N-methyltransferase activity 1/235 97/18367 0.714179038103695 0.838814161096861 PRMT1 1 GO:0004867 serine-type endopeptidase inhibitor activity 1/235 98/18367 0.717855443470178 0.840803060860098 SERPINB1 1 GO:0004725 protein tyrosine phosphatase activity 1/235 102/18367 0.73209613752172 0.855120557325645 PTPMT1 1 GO:0031490 chromatin DNA binding 1/235 103/18367 0.735543025432062 0.856786381272511 SMARCB1 1 GO:0019208 phosphatase regulator activity 1/235 107/18367 0.748894557199282 0.867571836755452 PPP1R14B 1 GO:1902936 phosphatidylinositol bisphosphate binding 1/235 107/18367 0.748894557199282 0.867571836755452 PFN1 1 GO:0003712 transcription coregulator activity 5/235 489/18367 0.753318986391862 0.870255881387219 SUB1/NPM1/C1QBP/VGLL1/SMARCB1 5 GO:0042626 ATPase-coupled transmembrane transporter activity 1/235 109/18367 0.755316425354945 0.870255881387219 ATP6V1E1 1 GO:0008047 enzyme activator activity 1/235 110/18367 0.758465764824854 0.871516217576525 KRTCAP2 1 GO:0017124 SH3 domain binding 1/235 130/18367 0.813623515715885 0.932368569360907 GPX1 1 GO:0043177 organic acid binding 1/235 135/18367 0.825327392967732 0.943231306248836 S100A9 1 GO:0020037 heme binding 1/235 139/18367 0.834161197275624 0.950764375389421 CYCS 1 GO:0070851 growth factor receptor binding 1/235 141/18367 0.838409820790451 0.953044943740352 IL6ST 1 GO:0016922 nuclear receptor binding 1/235 144/18367 0.844580380410959 0.954938883451325 ISL1 1 GO:0140375 immune receptor activity 1/235 144/18367 0.844580380410959 0.954938883451325 IL6ST 1 GO:0042578 phosphoric ester hydrolase activity 3/235 366/18367 0.850431623118253 0.957889148344299 PPP4C/HDDC2/PTPMT1 3 GO:0046906 tetrapyrrole binding 1/235 149/18367 0.854347566100073 0.957889148344299 CYCS 1 GO:0019903 protein phosphatase binding 1/235 150/18367 0.856226384958701 0.957889148344299 EGFR 1 GO:0140677 molecular function activator activity 1/235 150/18367 0.856226384958701 0.957889148344299 KRTCAP2 1 GO:0015103 inorganic anion transmembrane transporter activity 1/235 152/18367 0.859911930268976 0.959480680089595 CLIC3 1 GO:0048018 receptor ligand activity 4/235 487/18367 0.873300596698092 0.969802191042985 MIF/MANF/FBN1/CSH1 4 GO:0140030 modification-dependent protein binding 1/235 160/18367 0.873736879666086 0.969802191042985 MORC4 1 GO:0030546 signaling receptor activator activity 4/235 495/18367 0.881148139523233 0.975474702762012 MIF/MANF/FBN1/CSH1 4 GO:0033218 amide binding 3/235 400/18367 0.889158079787799 0.981778713099028 ACBD6/PFDN2/PFDN4 3 GO:1901981 phosphatidylinositol phosphate binding 1/235 173/18367 0.893363370793104 0.982824010343201 PFN1 1 GO:0004252 serine-type endopeptidase activity 1/235 174/18367 0.894740726397348 0.982824010343201 SEC11A 1 GO:0008514 organic anion transmembrane transporter activity 1/235 185/18367 0.908770917826962 0.983935376787907 SLC25A5 1 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/235 310/18367 0.909223898106751 0.983935376787907 ENO1/PEG3 2 GO:0003714 transcription corepressor activity 1/235 187/18367 0.911113990008619 0.983935376787907 C1QBP 1 GO:0001217 DNA-binding transcription repressor activity 2/235 313/18367 0.912031818534185 0.983935376787907 ENO1/PEG3 2 GO:0008509 anion transmembrane transporter activity 2/235 314/18367 0.912949628656653 0.983935376787907 SLC25A5/CLIC3 2 GO:0008236 serine-type peptidase activity 1/235 191/18367 0.915621875207681 0.983935376787907 SEC11A 1 GO:0042277 peptide binding 2/235 321/18367 0.919127971241179 0.983935376787907 PFDN2/PFDN4 2 GO:0017171 serine hydrolase activity 1/235 195/18367 0.919902064938703 0.983935376787907 SEC11A 1 GO:0019902 phosphatase binding 1/235 196/18367 0.920937890094955 0.983935376787907 EGFR 1 GO:0016758 hexosyltransferase activity 1/235 197/18367 0.921960376244736 0.983935376787907 OSTC 1 GO:0005244 voltage-gated ion channel activity 1/235 201/18367 0.925920319194281 0.983935376787907 CLIC3 1 GO:0005516 calmodulin binding 1/235 201/18367 0.925920319194281 0.983935376787907 EGFR 1 GO:0022832 voltage-gated channel activity 1/235 201/18367 0.925920319194281 0.983935376787907 CLIC3 1 GO:0005096 GTPase activator activity 3/235 462/18367 0.937440135155552 0.993592202593374 EEF1B2/RANBP1/NRP1 3 GO:0005543 phospholipid binding 3/235 466/18367 0.939767654650176 0.993592202593374 PFN1/ANXA1/ANXA4 3 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/235 222/18367 0.943651485674031 0.993592202593374 SAT1 1 GO:0005085 guanyl-nucleotide exchange factor activity 1/235 223/18367 0.944381268030966 0.993592202593374 EEF1B2 1 GO:0030695 GTPase regulator activity 3/235 488/18367 0.951202307893216 0.994664335032196 EEF1B2/RANBP1/NRP1 3 GO:0060589 nucleoside-triphosphatase regulator activity 3/235 488/18367 0.951202307893216 0.994664335032196 EEF1B2/RANBP1/NRP1 3 GO:0005125 cytokine activity 1/235 235/18367 0.952438018922339 0.994664335032196 MIF 1 GO:0015291 secondary active transmembrane transporter activity 1/235 240/18367 0.955441616319082 0.995349497098995 SLC25A5 1 GO:0140098 catalytic activity, acting on RNA 2/235 386/18367 0.959790882993213 0.996134479176385 POLR2G/EIF4A1 2 GO:0016746 acyltransferase activity 1/235 250/18367 0.960893872601749 0.996134479176385 SAT1 1 GO:0016757 glycosyltransferase activity 1/235 270/18367 0.969885126971864 0.996515176286651 OSTC 1 GO:0030246 carbohydrate binding 1/235 271/18367 0.970276185996101 0.996515176286651 ALDOA 1 GO:0035091 phosphatidylinositol binding 1/235 271/18367 0.970276185996101 0.996515176286651 PFN1 1 GO:0016887 ATP hydrolysis activity 1/235 272/18367 0.970662188222611 0.996515176286651 EIF4A1 1 GO:0001664 G protein-coupled receptor binding 1/235 295/18367 0.978284306799802 0.998120730034337 C1QBP 1 GO:0030674 protein-macromolecule adaptor activity 1/235 296/18367 0.978566687715143 0.998120730034337 CAV1 1 GO:0022836 gated channel activity 1/235 340/18367 0.987959029760145 0.998120730034337 CLIC3 1 GO:0060090 molecular adaptor activity 1/235 369/18367 0.991772456647373 0.998120730034337 CAV1 1 GO:0004674 protein serine/threonine kinase activity 1/235 386/18367 0.993420515047259 0.998120730034337 EGFR 1 GO:0004175 endopeptidase activity 1/235 430/18367 0.996314462586728 0.998120730034337 SEC11A 1 GO:0005216 ion channel activity 1/235 432/18367 0.996410404109361 0.998120730034337 CLIC3 1 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 1/235 450/18367 0.997169323272844 0.998120730034337 ISL1 1 GO:0001216 DNA-binding transcription activator activity 1/235 456/18367 0.997384937961373 0.998120730034337 ISL1 1 GO:0015267 channel activity 1/235 480/18367 0.998095711427837 0.998120730034337 CLIC3 1 GO:0022803 passive transmembrane transporter activity 1/235 481/18367 0.998120730034337 0.998120730034337 CLIC3 1