ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0009055 electron transfer activity 30/1082 116/18639 0.258620689655172 4.45511186181401 2.34835603382851e-12 2.36714288209914e-09 GO:0044389 ubiquitin-like protein ligase binding 49/1082 322/18639 0.152173913043478 2.62141364622679 5.52583655213348e-10 2.78502162227527e-07 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 19/1082 68/18639 0.279411764705882 4.81326791345004 6.15139796084971e-09 2.0668697148455e-06 GO:0008135 translation factor activity, RNA binding 20/1082 83/18639 0.240963855421687 4.15094759815602 3.91689271528741e-08 8.1706155667121e-06 GO:0045296 cadherin binding 46/1082 334/18639 0.137724550898204 2.37250268409576 4.41678824646453e-08 8.1706155667121e-06 GO:0180051 translation factor activity 20/1082 84/18639 0.238095238095238 4.10153155532083 4.86346164685244e-08 8.1706155667121e-06 GO:0022853 active monoatomic ion transmembrane transporter activity 24/1082 118/18639 0.203389830508475 3.50368119301983 6.07106121666953e-08 8.74232815200412e-06 GO:0031625 ubiquitin protein ligase binding 42/1082 302/18639 0.139072847682119 2.39572902767747 1.29049225854662e-07 1.55692946983416e-05 GO:0042605 peptide antigen binding 14/1082 45/18639 0.311111111111111 5.35933456561922 1.39011559806622e-07 1.55692946983416e-05 GO:0003743 translation initiation factor activity 14/1082 51/18639 0.274509803921569 4.72882461672284 7.76210999708494e-07 7.73652072477606e-05 GO:0140297 DNA-binding transcription factor binding 56/1082 488/18639 0.114754098360656 1.97680373322021 8.44263174330721e-07 7.73652072477606e-05 GO:0015399 primary active transmembrane transporter activity 27/1082 166/18639 0.162650602409639 2.80188962875532 1.09476006642539e-06 9.19598455797324e-05 GO:0015078 proton transmembrane transporter activity 28/1082 185/18639 0.151351351351351 2.60724384273368 3.02267100451459e-06 0.000234373259426977 GO:0043021 ribonucleoprotein complex binding 27/1082 177/18639 0.152542372881356 2.62776089476487 3.88028773745351e-06 0.000279380717096653 GO:0004129 cytochrome-c oxidase activity 7/1082 15/18639 0.466666666666667 8.03900184842884 9.28467445507351e-06 0.00062393012338094 GO:0140313 molecular sequestering activity 13/1082 55/18639 0.236363636363636 4.0717022349185 1.17013893506865e-05 0.00073718752909325 GO:0038187 pattern recognition receptor activity 12/1082 48/18639 0.25 4.30660813308688 1.36968683812439e-05 0.000812143725193755 GO:0016675 oxidoreductase activity, acting on a heme group of donors 7/1082 16/18639 0.4375 7.53656423290203 1.56782850906932e-05 0.000877983965078821 GO:0042277 peptide binding 32/1082 249/18639 0.1285140562249 2.21383871901655 2.06027139726659e-05 0.00100401031709275 GO:0004857 enzyme inhibitor activity 46/1082 416/18639 0.110576923076923 1.9048459050192 2.07434496191371e-05 0.00100401031709275 GO:0031072 heat shock protein binding 21/1082 131/18639 0.16030534351145 2.76148918457479 2.09168816060989e-05 0.00100401031709275 GO:0003735 structural constituent of ribosome 24/1082 175/18639 0.137142857142857 2.3624821758648 7.72489073775579e-05 0.00353940448348084 GO:0023026 MHC class II protein complex binding 8/1082 27/18639 0.296296296296296 5.10412815773259 0.00010346935768978 0.00435567805843225 GO:0003924 GTPase activity 37/1082 331/18639 0.11178247734139 1.92561330422011 0.000103706620438863 0.00435567805843225 GO:0002020 protease binding 20/1082 136/18639 0.147058823529412 2.53329890181581 0.000113476169762108 0.00457535916480819 GO:0061135 endopeptidase regulator activity 24/1082 184/18639 0.130434782608696 2.24692598248011 0.000170215246030752 0.00641440792467998 GO:0061133 endopeptidase activator activity 7/1082 22/18639 0.318181818181818 5.48113762392875 0.0001718144979825 0.00641440792467998 GO:0005525 GTP binding 40/1082 378/18639 0.105820105820106 1.82290291347593 0.000181469552267241 0.00653290388162067 GO:0003779 actin binding 45/1082 443/18639 0.101580135440181 1.74986334978699 0.000189387892556237 0.0065828619205754 GO:0023023 MHC protein complex binding 9/1082 37/18639 0.243243243243243 4.19021331867912 0.00020561955800305 0.00690881714890249 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 11/1082 54/18639 0.203703703703704 3.50908810844116 0.000228699690211682 0.00743642863656049 GO:0043022 ribosome binding 17/1082 112/18639 0.151785714285714 2.61472636651703 0.000245692312005787 0.00773930782818228 GO:0051087 protein-folding chaperone binding 19/1082 134/18639 0.141791044776119 2.44255386652689 0.000270002012589957 0.00819138535644737 GO:0019001 guanyl nucleotide binding 41/1082 400/18639 0.1025 1.76570933456562 0.000297692232255062 0.00819138535644737 GO:0032561 guanyl ribonucleotide binding 41/1082 400/18639 0.1025 1.76570933456562 0.000297692232255062 0.00819138535644737 GO:0061134 peptidase regulator activity 27/1082 226/18639 0.119469026548673 2.05802512554594 0.000299268254194258 0.00819138535644737 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 37/1082 349/18639 0.106017191977077 1.82629800486206 0.000300675851377532 0.00819138535644737 GO:0003725 double-stranded RNA binding 13/1082 75/18639 0.173333333333333 2.98591497227357 0.0003473120872052 0.0089766816385344 GO:0019003 GDP binding 13/1082 75/18639 0.173333333333333 2.98591497227357 0.0003473120872052 0.0089766816385344 GO:0015036 disulfide oxidoreductase activity 9/1082 40/18639 0.225 3.87594731977819 0.000386302102461041 0.00973481298201823 GO:0016209 antioxidant activity 14/1082 86/18639 0.162790697674419 2.80430297038215 0.000408402707531562 0.0100407299802882 GO:0008137 NADH dehydrogenase (ubiquinone) activity 9/1082 41/18639 0.219512195121951 3.78141201929579 0.000469754143698389 0.0112740994487613 GO:0016651 oxidoreductase activity, acting on NAD(P)H 14/1082 88/18639 0.159090909090909 2.74056881196438 0.000519674622724366 0.0121821399931665 GO:0051082 unfolded protein binding 17/1082 121/18639 0.140495867768595 2.42024258718932 0.000618808172936704 0.0141763326890954 GO:0005126 cytokine receptor binding 30/1082 275/18639 0.109090909090909 1.879247185347 0.000676434695392894 0.0151521371768008 GO:0001671 ATPase activator activity 7/1082 27/18639 0.259259259259259 4.46611213801602 0.000693193548670508 0.0151899803708668 GO:0003954 NADH dehydrogenase activity 9/1082 44/18639 0.204545454545455 3.52358847252563 0.000812839414615068 0.0174328112751487 GO:0042379 chemokine receptor binding 12/1082 72/18639 0.166666666666667 2.87107208872458 0.000835308197523468 0.0175414721479928 GO:0051019 mitogen-activated protein kinase binding 7/1082 28/18639 0.25 4.30660813308688 0.000878414430131018 0.0180702397055524 GO:0003925 G protein activity 10/1082 54/18639 0.185185185185185 3.19008009858287 0.000963316044505902 0.0190624630045702 GO:0008009 chemokine activity 9/1082 45/18639 0.2 3.4452865064695 0.000964469854397898 0.0190624630045702 GO:0051015 actin filament binding 24/1082 209/18639 0.114832535885167 1.97815493194421 0.00110745360815895 0.0214675622504658 GO:0031386 protein tag activity 5/1082 15/18639 0.333333333333333 5.74214417744917 0.00120180627742787 0.0220258314117689 GO:0050700 CARD domain binding 5/1082 15/18639 0.333333333333333 5.74214417744917 0.00120180627742787 0.0220258314117689 GO:0141047 molecular tag activity 5/1082 15/18639 0.333333333333333 5.74214417744917 0.00120180627742787 0.0220258314117689 GO:0140517 protein-RNA adaptor activity 6/1082 22/18639 0.272727272727273 4.6981179633675 0.00125941625772141 0.0226694926389853 GO:0004601 peroxidase activity 10/1082 57/18639 0.175438596491228 3.02218114602588 0.00148506282572337 0.0262621636548976 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 8/1082 39/18639 0.205128205128205 3.53362718612256 0.00154244699257161 0.026806664974348 GO:0004602 glutathione peroxidase activity 6/1082 23/18639 0.260869565217391 4.49385196496022 0.00162108991717081 0.0276959090933589 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 10/1082 58/18639 0.172413793103448 2.97007457454267 0.00170281378124533 0.0286072715249216 GO:0060590 ATPase regulator activity 9/1082 49/18639 0.183673469387755 3.16403862839036 0.00181607182230457 0.0296367894686123 GO:0003727 single-stranded RNA binding 13/1082 89/18639 0.146067415730337 2.51622048225301 0.00182289776493448 0.0296367894686123 GO:0019887 protein kinase regulator activity 27/1082 255/18639 0.105882352941176 1.82397520930738 0.00189493038841149 0.0302400459392945 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 10/1082 59/18639 0.169491525423729 2.91973432751653 0.00194568958026054 0.0302400459392945 GO:0003712 transcription coregulator activity 45/1082 495/18639 0.0909090909090909 1.5660393211225 0.0019500029623553 0.0302400459392945 GO:0001091 RNA polymerase II general transcription initiation factor binding 6/1082 24/18639 0.25 4.30660813308688 0.00205651699213344 0.0304848401186839 GO:0035035 histone acetyltransferase binding 6/1082 24/18639 0.25 4.30660813308688 0.00205651699213344 0.0304848401186839 GO:0060229 lipase activator activity 6/1082 24/18639 0.25 4.30660813308688 0.00205651699213344 0.0304848401186839 GO:0061650 ubiquitin-like protein conjugating enzyme activity 8/1082 41/18639 0.195121951219512 3.36125512826293 0.00216159935362067 0.0315781470789802 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 5/1082 17/18639 0.294117647058824 5.06659780363162 0.00224715109267042 0.032358975734454 GO:0140311 protein sequestering activity 7/1082 33/18639 0.212121212121212 3.65409174928583 0.00245945905334419 0.0349173905038162 GO:0016859 cis-trans isomerase activity 8/1082 42/18639 0.19047619047619 3.28122524425667 0.00253669212714695 0.0355136897800574 GO:0032050 clathrin heavy chain binding 4/1082 11/18639 0.363636363636364 6.26415728449 0.00268103901275001 0.0370203743130413 GO:0015035 protein-disulfide reductase activity 7/1082 34/18639 0.205882352941176 3.54661846254213 0.00294440961572466 0.0398394769105919 GO:0003746 translation elongation factor activity 5/1082 18/18639 0.277777777777778 4.78512014787431 0.00296424679394285 0.0398394769105919 GO:0019208 phosphatase regulator activity 15/1082 117/18639 0.128205128205128 2.2085169913266 0.00316184350408913 0.0419360296331821 GO:0048029 monosaccharide binding 11/1082 74/18639 0.148648648648649 2.56068591697058 0.00346732667726195 0.0453904583205201 GO:0019888 protein phosphatase regulator activity 14/1082 107/18639 0.130841121495327 2.25392575189594 0.00354507431101937 0.0458132680193272 GO:0004859 phospholipase inhibitor activity 4/1082 12/18639 0.333333333333333 5.74214417744917 0.00383810651271072 0.0477631032692889 GO:0070008 serine-type exopeptidase activity 4/1082 12/18639 0.333333333333333 5.74214417744917 0.00383810651271072 0.0477631032692889 GO:0097677 STAT family protein binding 4/1082 12/18639 0.333333333333333 5.74214417744917 0.00383810651271072 0.0477631032692889 GO:0038024 cargo receptor activity 10/1082 65/18639 0.153846153846154 2.65022038959192 0.00405160699719738 0.0498051201606702 GO:0016004 phospholipase activator activity 5/1082 20/18639 0.25 4.30660813308688 0.00486955534061267 0.058278456453193 GO:0043024 ribosomal small subunit binding 5/1082 20/18639 0.25 4.30660813308688 0.00486955534061267 0.058278456453193 GO:0005125 cytokine activity 24/1082 234/18639 0.102564102564103 1.76681359306128 0.00491435396678711 0.058278456453193 GO:0019207 kinase regulator activity 28/1082 287/18639 0.0975609756097561 1.68062756413146 0.00507124884163011 0.0594397538646879 GO:0016504 peptidase activator activity 9/1082 57/18639 0.157894736842105 2.71996303142329 0.00525603044502353 0.0608974561906175 GO:0030544 Hsp70 protein binding 8/1082 51/18639 0.156862745098039 2.7021854952702 0.00864323254405439 0.0990043000500776 GO:0051117 ATPase binding 11/1082 84/18639 0.130952380952381 2.25584235542646 0.00912169375445085 0.103310868589735 GO:0030414 peptidase inhibitor activity 18/1082 169/18639 0.106508875739645 1.83476796202518 0.0094463783552881 0.105799437579227 GO:0030296 protein tyrosine kinase activator activity 6/1082 33/18639 0.181818181818182 3.132078642245 0.010845137644098 0.116859129028252 GO:0140296 general transcription initiation factor binding 8/1082 53/18639 0.150943396226415 2.60021623129774 0.0108686170403824 0.116859129028252 GO:0042625 ATPase-coupled ion transmembrane transporter activity 5/1082 24/18639 0.208333333333333 3.58884011090573 0.0110135091842103 0.116859129028252 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 5/1082 24/18639 0.208333333333333 3.58884011090573 0.0110135091842103 0.116859129028252 GO:0046961 proton-transporting ATPase activity, rotational mechanism 5/1082 24/18639 0.208333333333333 3.58884011090573 0.0110135091842103 0.116859129028252 GO:0008200 ion channel inhibitor activity 7/1082 43/18639 0.162790697674419 2.80430297038215 0.011217892525202 0.117787871514621 GO:0055102 lipase inhibitor activity 4/1082 16/18639 0.25 4.30660813308688 0.0117199673066964 0.121791000465463 GO:0004866 endopeptidase inhibitor activity 17/1082 161/18639 0.105590062111801 1.81894008105533 0.0124013274604949 0.127556511022233 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 6/1082 34/18639 0.176470588235294 3.03995868217897 0.0125381507930351 0.127661171710903 GO:0016248 channel inhibitor activity 7/1082 44/18639 0.159090909090909 2.74056881196438 0.0126897384432416 0.127912563507875 GO:0019211 phosphatase activator activity 5/1082 25/18639 0.2 3.4452865064695 0.0131232020268727 0.130972154882056 GO:0141110 transporter inhibitor activity 7/1082 45/18639 0.155555555555556 2.67966728280961 0.0142954567055057 0.141005181259691 GO:0005154 epidermal growth factor receptor binding 6/1082 35/18639 0.171428571428571 2.953102719831 0.0144082675295121 0.141005181259691 GO:0008429 phosphatidylethanolamine binding 4/1082 17/18639 0.235294117647059 4.0532782429053 0.0146346799879351 0.141843821421525 GO:0000287 magnesium ion binding 22/1082 230/18639 0.0956521739130435 1.64774572048541 0.0148587589405346 0.142644085829133 GO:0008157 protein phosphatase 1 binding 5/1082 26/18639 0.192307692307692 3.31277548698991 0.0154894242880082 0.147295657380304 GO:0005484 SNAP receptor activity 6/1082 36/18639 0.166666666666667 2.87107208872458 0.0164638814037576 0.149335488172654 GO:0055106 ubiquitin-protein transferase regulator activity 6/1082 36/18639 0.166666666666667 2.87107208872458 0.0164638814037576 0.149335488172654 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 6/1082 36/18639 0.166666666666667 2.87107208872458 0.0164638814037576 0.149335488172654 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 6/1082 36/18639 0.166666666666667 2.87107208872458 0.0164638814037576 0.149335488172654 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 6/1082 36/18639 0.166666666666667 2.87107208872458 0.0164638814037576 0.149335488172654 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 14/1082 128/18639 0.109375 1.88414105822551 0.0165928320191838 0.149335488172654 GO:0016175 superoxide-generating NAD(P)H oxidase activity 3/1082 10/18639 0.3 5.16792975970425 0.0172088700949089 0.149539147031622 GO:0030957 Tat protein binding 3/1082 10/18639 0.3 5.16792975970425 0.0172088700949089 0.149539147031622 GO:0032395 MHC class II receptor activity 3/1082 10/18639 0.3 5.16792975970425 0.0172088700949089 0.149539147031622 GO:1990757 ubiquitin ligase activator activity 3/1082 10/18639 0.3 5.16792975970425 0.0172088700949089 0.149539147031622 GO:0030228 lipoprotein particle receptor activity 4/1082 18/18639 0.222222222222222 3.82809611829945 0.0179690894719329 0.154810616988961 GO:0061980 regulatory RNA binding 8/1082 58/18639 0.137931034482759 2.37605965963414 0.0182498897807153 0.155897363550517 GO:0031593 polyubiquitin modification-dependent protein binding 8/1082 59/18639 0.135593220338983 2.33578746201322 0.0200738729421474 0.169830757335978 GO:0019903 protein phosphatase binding 15/1082 144/18639 0.104166666666667 1.79442005545287 0.0202179473019021 0.169830757335978 GO:0046966 nuclear thyroid hormone receptor binding 5/1082 28/18639 0.178571428571429 3.07614866649063 0.0210379209638227 0.17433634507423 GO:0042162 telomeric DNA binding 6/1082 38/18639 0.157894736842105 2.71996303142329 0.0211630609921138 0.17433634507423 GO:0016763 pentosyltransferase activity 7/1082 49/18639 0.142857142857143 2.4609189331925 0.022175020905186 0.17433634507423 GO:0035254 glutamate receptor binding 7/1082 49/18639 0.142857142857143 2.4609189331925 0.022175020905186 0.17433634507423 GO:0008199 ferric iron binding 3/1082 11/18639 0.272727272727273 4.6981179633675 0.0226568067507184 0.17433634507423 GO:0016176 superoxide-generating NADPH oxidase activator activity 3/1082 11/18639 0.272727272727273 4.6981179633675 0.0226568067507184 0.17433634507423 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 3/1082 11/18639 0.272727272727273 4.6981179633675 0.0226568067507184 0.17433634507423 GO:0019864 IgG binding 3/1082 11/18639 0.272727272727273 4.6981179633675 0.0226568067507184 0.17433634507423 GO:0042608 T cell receptor binding 3/1082 11/18639 0.272727272727273 4.6981179633675 0.0226568067507184 0.17433634507423 GO:0050786 RAGE receptor binding 3/1082 11/18639 0.272727272727273 4.6981179633675 0.0226568067507184 0.17433634507423 GO:0140537 transcription regulator activator activity 3/1082 11/18639 0.272727272727273 4.6981179633675 0.0226568067507184 0.17433634507423 GO:0004860 protein kinase inhibitor activity 10/1082 84/18639 0.119047619047619 2.05076577766042 0.0233611037805104 0.178393883414807 GO:0019905 syntaxin binding 8/1082 61/18639 0.131147540983607 2.25920426653738 0.0241035861803817 0.180389652078228 GO:0003785 actin monomer binding 5/1082 29/18639 0.172413793103448 2.97007457454267 0.0242407009033874 0.180389652078228 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 5/1082 29/18639 0.172413793103448 2.97007457454267 0.0242407009033874 0.180389652078228 GO:0001664 G protein-coupled receptor binding 26/1082 297/18639 0.0875420875420875 1.50803786478463 0.024338286391507 0.180389652078228 GO:0048020 CCR chemokine receptor binding 7/1082 50/18639 0.14 2.41170055452865 0.0245366775776901 0.180532635024172 GO:0000339 RNA cap binding 4/1082 20/18639 0.2 3.4452865064695 0.0259560356419286 0.188163288563983 GO:0042288 MHC class I protein binding 4/1082 20/18639 0.2 3.4452865064695 0.0259560356419286 0.188163288563983 GO:0044325 transmembrane transporter binding 14/1082 136/18639 0.102941176470588 1.77330923127107 0.0265856673053278 0.188163288563983 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 6/1082 40/18639 0.15 2.58396487985213 0.0266937998657238 0.188163288563983 GO:0061791 GTPase motor activity 6/1082 40/18639 0.15 2.58396487985213 0.0266937998657238 0.188163288563983 GO:1990606 membrane scission GTPase motor activity 6/1082 40/18639 0.15 2.58396487985213 0.0266937998657238 0.188163288563983 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 10/1082 86/18639 0.116279069767442 2.00307355027297 0.0270351468359535 0.189246027851674 GO:0005507 copper ion binding 8/1082 63/18639 0.126984126984127 2.18748349617111 0.0286682654815365 0.195712379091911 GO:0004126 cytidine deaminase activity 3/1082 12/18639 0.25 4.30660813308688 0.0289297068300544 0.195712379091911 GO:0016208 AMP binding 3/1082 12/18639 0.25 4.30660813308688 0.0289297068300544 0.195712379091911 GO:0035259 nuclear glucocorticoid receptor binding 3/1082 12/18639 0.25 4.30660813308688 0.0289297068300544 0.195712379091911 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/1082 12/18639 0.25 4.30660813308688 0.0289297068300544 0.195712379091911 GO:0005200 structural constituent of cytoskeleton 12/1082 112/18639 0.107142857142857 1.84568919989438 0.0291942196143076 0.196185155808147 GO:0001530 lipopolysaccharide binding 6/1082 41/18639 0.146341463414634 2.5209413461972 0.0297868720488684 0.198842165730194 GO:0043130 ubiquitin binding 11/1082 100/18639 0.11 1.89490757855823 0.0302874064521144 0.200853326998232 GO:0072542 protein phosphatase activator activity 4/1082 21/18639 0.19047619047619 3.28122524425667 0.0306302988198383 0.201799615754229 GO:0030295 protein kinase activator activity 14/1082 139/18639 0.100719424460432 1.7350363701645 0.0312946063862326 0.204837423618977 GO:0005164 tumor necrosis factor receptor binding 5/1082 31/18639 0.161290322580645 2.77845686005605 0.0315458881219535 0.205150033722123 GO:0042056 chemoattractant activity 6/1082 42/18639 0.142857142857143 2.4609189331925 0.033105731368442 0.213913956534548 GO:0017124 SH3 domain binding 12/1082 115/18639 0.104347826086957 1.79754078598409 0.0348738069679763 0.222756529226068 GO:0016247 channel regulator activity 16/1082 168/18639 0.0952380952380952 1.64061262212833 0.0353076879390062 0.222756529226068 GO:0019210 kinase inhibitor activity 10/1082 90/18639 0.111111111111111 1.91404805914972 0.0355857174714079 0.222756529226068 GO:0051059 NF-kappaB binding 5/1082 32/18639 0.15625 2.6916300831793 0.0356617065131643 0.222756529226068 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 3/1082 13/18639 0.230769230769231 3.97533058438789 0.036021145103025 0.222756529226068 GO:0035325 Toll-like receptor binding 3/1082 13/18639 0.230769230769231 3.97533058438789 0.036021145103025 0.222756529226068 GO:0089720 caspase binding 3/1082 13/18639 0.230769230769231 3.97533058438789 0.036021145103025 0.222756529226068 GO:0140375 immune receptor activity 15/1082 156/18639 0.0961538461538462 1.65638774349495 0.0378150986590982 0.23242450883153 GO:0141108 transporter regulator activity 16/1082 170/18639 0.0941176470588235 1.62131129716212 0.0387268876776958 0.236586077449196 GO:0140416 transcription regulator inhibitor activity 5/1082 33/18639 0.151515151515152 2.61006553520417 0.0400932366683547 0.243457726275311 GO:1901981 phosphatidylinositol phosphate binding 17/1082 185/18639 0.0918918918918919 1.58296947594545 0.0411133500667006 0.248157226749905 GO:0043274 phospholipase binding 4/1082 23/18639 0.173913043478261 2.99590130997348 0.0413721457535988 0.248232874521593 GO:0048306 calcium-dependent protein binding 9/1082 80/18639 0.1125 1.93797365988909 0.0418455417884808 0.249587610194016 GO:0003713 transcription coactivator activity 22/1082 256/18639 0.0859375 1.48039654574861 0.0428547500765686 0.254103459277536 GO:0000149 SNARE binding 11/1082 106/18639 0.10377358490566 1.78764865901719 0.0436377311031696 0.255883063429653 GO:0016530 metallochaperone activity 3/1082 14/18639 0.214285714285714 3.69137839978875 0.0439164384656051 0.255883063429653 GO:0044548 S100 protein binding 3/1082 14/18639 0.214285714285714 3.69137839978875 0.0439164384656051 0.255883063429653 GO:0032182 ubiquitin-like protein binding 12/1082 120/18639 0.1 1.72264325323475 0.0460124104437908 0.266554653605409 GO:0048027 mRNA 5'-UTR binding 4/1082 24/18639 0.166666666666667 2.87107208872458 0.0474438730674765 0.273276708868664 GO:0004180 carboxypeptidase activity 6/1082 46/18639 0.130434782608696 2.24692598248011 0.048724237139197 0.279056994524492 GO:0019209 kinase activator activity 14/1082 148/18639 0.0945945945945946 1.62952740170855 0.0490288892665276 0.279215369382259 GO:0003714 transcription corepressor activity 18/1082 204/18639 0.0882352941176471 1.51997934108949 0.0506999060073401 0.287091008500219 GO:0001540 amyloid-beta binding 9/1082 83/18639 0.108433734939759 1.86792641917021 0.0509814390094635 0.287091008500219 GO:0004953 icosanoid receptor activity 3/1082 15/18639 0.2 3.4452865064695 0.0525939840707847 0.289698010619404 GO:0005041 low-density lipoprotein particle receptor activity 3/1082 15/18639 0.2 3.4452865064695 0.0525939840707847 0.289698010619404 GO:0017081 chloride channel regulator activity 3/1082 15/18639 0.2 3.4452865064695 0.0525939840707847 0.289698010619404 GO:0140776 protein-containing complex destabilizing activity 3/1082 15/18639 0.2 3.4452865064695 0.0525939840707847 0.289698010619404 GO:0001784 phosphotyrosine residue binding 6/1082 47/18639 0.127659574468085 2.19911904668266 0.0532303439814572 0.290978571613969 GO:0001786 phosphatidylserine binding 7/1082 59/18639 0.11864406779661 2.04381402926157 0.0537752737331639 0.290978571613969 GO:0045309 protein phosphorylated amino acid binding 7/1082 59/18639 0.11864406779661 2.04381402926157 0.0537752737331639 0.290978571613969 GO:0005537 D-mannose binding 4/1082 25/18639 0.16 2.7562292051756 0.0539811437418772 0.290978571613969 GO:1902936 phosphatidylinositol bisphosphate binding 11/1082 111/18639 0.0990990990990991 1.70712394464705 0.057478800186814 0.30818420525696 GO:0030246 carbohydrate binding 23/1082 280/18639 0.0821428571428571 1.41502838658569 0.0593003869725085 0.316268730520045 GO:0001637 G protein-coupled chemoattractant receptor activity 4/1082 26/18639 0.153846153846154 2.65022038959192 0.0609796381880353 0.317373914079721 GO:0004950 chemokine receptor activity 4/1082 26/18639 0.153846153846154 2.65022038959192 0.0609796381880353 0.317373914079721 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 4/1082 26/18639 0.153846153846154 2.65022038959192 0.0609796381880353 0.317373914079721 GO:0005521 lamin binding 3/1082 16/18639 0.1875 3.22995609981516 0.0620264494778821 0.317373914079721 GO:0008142 oxysterol binding 3/1082 16/18639 0.1875 3.22995609981516 0.0620264494778821 0.317373914079721 GO:0043023 ribosomal large subunit binding 3/1082 16/18639 0.1875 3.22995609981516 0.0620264494778821 0.317373914079721 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 3/1082 16/18639 0.1875 3.22995609981516 0.0620264494778821 0.317373914079721 GO:0097027 ubiquitin-protein transferase activator activity 3/1082 16/18639 0.1875 3.22995609981516 0.0620264494778821 0.317373914079721 GO:0032813 tumor necrosis factor receptor superfamily binding 6/1082 50/18639 0.12 2.0671719038817 0.068219145221146 0.346634395496581 GO:0035255 ionotropic glutamate receptor binding 4/1082 27/18639 0.148148148148148 2.5520640788663 0.0684327824442655 0.346634395496581 GO:0004197 cysteine-type endopeptidase activity 9/1082 88/18639 0.102272727272727 1.76179423626281 0.0689352382457461 0.347433600758561 GO:0008238 exopeptidase activity 10/1082 102/18639 0.0980392156862745 1.68886593454387 0.0719786126137394 0.355352791399925 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 3/1082 17/18639 0.176470588235294 3.03995868217897 0.0721818286542992 0.355352791399925 GO:0045236 CXCR chemokine receptor binding 3/1082 17/18639 0.176470588235294 3.03995868217897 0.0721818286542992 0.355352791399925 GO:0048038 quinone binding 3/1082 17/18639 0.176470588235294 3.03995868217897 0.0721818286542992 0.355352791399925 GO:0005543 phospholipid binding 37/1082 497/18639 0.0744466800804829 1.2824507116637 0.0722691688858974 0.355352791399925 GO:0019789 SUMO transferase activity 4/1082 28/18639 0.142857142857143 2.4609189331925 0.0763319260243392 0.369916256887182 GO:0051537 2 iron, 2 sulfur cluster binding 4/1082 28/18639 0.142857142857143 2.4609189331925 0.0763319260243392 0.369916256887182 GO:0097718 disordered domain specific binding 4/1082 28/18639 0.142857142857143 2.4609189331925 0.0763319260243392 0.369916256887182 GO:0004177 aminopeptidase activity 5/1082 40/18639 0.125 2.15330406654344 0.0801088876413095 0.384522660678285 GO:0050997 quaternary ammonium group binding 5/1082 40/18639 0.125 2.15330406654344 0.0801088876413095 0.384522660678285 GO:0003823 antigen binding 15/1082 174/18639 0.0862068965517241 1.48503728727134 0.0815351081235502 0.387447090290272 GO:0099106 ion channel regulator activity 14/1082 160/18639 0.0875 1.50731284658041 0.0820980748316929 0.387447090290272 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 3/1082 18/18639 0.166666666666667 2.87107208872458 0.0830243764907725 0.387447090290272 GO:0032393 MHC class I receptor activity 3/1082 18/18639 0.166666666666667 2.87107208872458 0.0830243764907725 0.387447090290272 GO:0050811 GABA receptor binding 3/1082 18/18639 0.166666666666667 2.87107208872458 0.0830243764907725 0.387447090290272 GO:1990381 ubiquitin-specific protease binding 3/1082 18/18639 0.166666666666667 2.87107208872458 0.0830243764907725 0.387447090290272 GO:0004864 protein phosphatase inhibitor activity 6/1082 53/18639 0.113207547169811 1.9501621734733 0.0854119150999652 0.393887351649774 GO:0005544 calcium-dependent phospholipid binding 6/1082 53/18639 0.113207547169811 1.9501621734733 0.0854119150999652 0.393887351649774 GO:0019902 phosphatase binding 16/1082 190/18639 0.0842105263157895 1.45064695009242 0.0867146418971251 0.393887351649774 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/1082 41/18639 0.121951219512195 2.10078445516433 0.087098056473593 0.393887351649774 GO:0017080 sodium channel regulator activity 5/1082 41/18639 0.121951219512195 2.10078445516433 0.087098056473593 0.393887351649774 GO:0042287 MHC protein binding 5/1082 41/18639 0.121951219512195 2.10078445516433 0.087098056473593 0.393887351649774 GO:0046332 SMAD binding 8/1082 79/18639 0.10126582278481 1.74444886403519 0.0871397613272814 0.393887351649774 GO:0008083 growth factor activity 14/1082 162/18639 0.0864197530864197 1.48870404600534 0.0887306819692243 0.399288068861509 GO:0017069 snRNA binding 6/1082 54/18639 0.111111111111111 1.91404805914972 0.0916264385367809 0.406869823987115 GO:0051287 NAD binding 6/1082 54/18639 0.111111111111111 1.91404805914972 0.0916264385367809 0.406869823987115 GO:0140463 chromatin-protein adaptor activity 6/1082 54/18639 0.111111111111111 1.91404805914972 0.0916264385367809 0.406869823987115 GO:0008106 alcohol dehydrogenase (NADP+) activity 4/1082 30/18639 0.133333333333333 2.29685767097967 0.0934243073223408 0.40714340546376 GO:0031210 phosphatidylcholine binding 4/1082 30/18639 0.133333333333333 2.29685767097967 0.0934243073223408 0.40714340546376 GO:0051721 protein phosphatase 2A binding 4/1082 30/18639 0.133333333333333 2.29685767097967 0.0934243073223408 0.40714340546376 GO:0035198 miRNA binding 5/1082 42/18639 0.119047619047619 2.05076577766042 0.0943943166229377 0.40714340546376 GO:0048487 beta-tubulin binding 5/1082 42/18639 0.119047619047619 2.05076577766042 0.0943943166229377 0.40714340546376 GO:0051879 Hsp90 protein binding 5/1082 42/18639 0.119047619047619 2.05076577766042 0.0943943166229377 0.40714340546376 GO:0070003 threonine-type peptidase activity 3/1082 19/18639 0.157894736842105 2.71996303142329 0.0945154334112301 0.40714340546376 GO:1990841 promoter-specific chromatin binding 7/1082 68/18639 0.102941176470588 1.77330923127107 0.098605070577565 0.422952813371002 GO:0004867 serine-type endopeptidase inhibitor activity 9/1082 95/18639 0.0947368421052632 1.63197781885397 0.0999708541116105 0.426994156544506 GO:0035091 phosphatidylinositol binding 22/1082 284/18639 0.0774647887323944 1.33444195673114 0.103201949817271 0.431039149561562 GO:0019212 phosphatase inhibitor activity 6/1082 56/18639 0.107142857142857 1.84568919989438 0.104765016213361 0.431039149561562 GO:0016407 acetyltransferase activity 9/1082 96/18639 0.09375 1.61497804990758 0.104967321717909 0.431039149561562 GO:0016408 C-acyltransferase activity 3/1082 20/18639 0.15 2.58396487985213 0.106614150664636 0.431039149561562 GO:0016505 peptidase activator activity involved in apoptotic process 3/1082 20/18639 0.15 2.58396487985213 0.106614150664636 0.431039149561562 GO:0030742 GTP-dependent protein binding 3/1082 20/18639 0.15 2.58396487985213 0.106614150664636 0.431039149561562 GO:0001046 core promoter sequence-specific DNA binding 5/1082 44/18639 0.113636363636364 1.95754915140313 0.109882922079727 0.431039149561562 GO:0097110 scaffold protein binding 7/1082 70/18639 0.1 1.72264325323475 0.110708832094769 0.431039149561562 GO:0001094 TFIID-class transcription factor complex binding 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0004090 carbonyl reductase (NADPH) activity 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0004955 prostaglandin receptor activity 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0005345 purine nucleobase transmembrane transporter activity 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0005522 profilin binding 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0005528 FK506 binding 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0031434 mitogen-activated protein kinase kinase binding 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0031720 haptoglobin binding 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0035256 G protein-coupled glutamate receptor binding 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0047429 nucleoside triphosphate diphosphatase activity 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0050308 sugar-phosphatase activity 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0070513 death domain binding 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0098505 G-rich strand telomeric DNA binding 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:1905394 retromer complex binding 2/1082 10/18639 0.2 3.4452865064695 0.111180733021831 0.431039149561562 GO:0030515 snoRNA binding 4/1082 32/18639 0.125 2.15330406654344 0.112152876826363 0.433142144984574 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/1082 21/18639 0.142857142857143 2.4609189331925 0.119278125972103 0.457157228060378 GO:0019200 carbohydrate kinase activity 3/1082 21/18639 0.142857142857143 2.4609189331925 0.119278125972103 0.457157228060378 GO:0019239 deaminase activity 4/1082 33/18639 0.121212121212121 2.08805242816333 0.122092137537812 0.466169979689829 GO:0031490 chromatin DNA binding 11/1082 128/18639 0.0859375 1.48039654574861 0.124614166736618 0.471069779895484 GO:0070888 E-box binding 6/1082 59/18639 0.101694915254237 1.75184059650992 0.126188845065268 0.471069779895484 GO:0008234 cysteine-type peptidase activity 15/1082 187/18639 0.0802139037433155 1.38179940099044 0.127913834462284 0.471069779895484 GO:0033218 amide binding 19/1082 247/18639 0.0769230769230769 1.32511019479596 0.12883726372638 0.471069779895484 GO:0004954 prostanoid receptor activity 2/1082 11/18639 0.181818181818182 3.132078642245 0.130852716637634 0.471069779895484 GO:0005536 D-glucose binding 2/1082 11/18639 0.181818181818182 3.132078642245 0.130852716637634 0.471069779895484 GO:0008432 JUN kinase binding 2/1082 11/18639 0.181818181818182 3.132078642245 0.130852716637634 0.471069779895484 GO:0010854 adenylate cyclase regulator activity 2/1082 11/18639 0.181818181818182 3.132078642245 0.130852716637634 0.471069779895484 GO:0015205 nucleobase transmembrane transporter activity 2/1082 11/18639 0.181818181818182 3.132078642245 0.130852716637634 0.471069779895484 GO:0015217 ADP transmembrane transporter activity 2/1082 11/18639 0.181818181818182 3.132078642245 0.130852716637634 0.471069779895484 GO:0019203 carbohydrate phosphatase activity 2/1082 11/18639 0.181818181818182 3.132078642245 0.130852716637634 0.471069779895484 GO:0034511 U3 snoRNA binding 2/1082 11/18639 0.181818181818182 3.132078642245 0.130852716637634 0.471069779895484 GO:0034713 type I transforming growth factor beta receptor binding 2/1082 11/18639 0.181818181818182 3.132078642245 0.130852716637634 0.471069779895484 GO:0047676 arachidonate-CoA ligase activity 2/1082 11/18639 0.181818181818182 3.132078642245 0.130852716637634 0.471069779895484 GO:0070990 snRNP binding 2/1082 11/18639 0.181818181818182 3.132078642245 0.130852716637634 0.471069779895484 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/1082 11/18639 0.181818181818182 3.132078642245 0.130852716637634 0.471069779895484 GO:0019825 oxygen binding 4/1082 34/18639 0.117647058823529 2.02663912145265 0.132391874070399 0.471465010940039 GO:0030332 cyclin binding 4/1082 34/18639 0.117647058823529 2.02663912145265 0.132391874070399 0.471465010940039 GO:0070034 telomerase RNA binding 3/1082 22/18639 0.136363636363636 2.34905898168375 0.13246395836201 0.471465010940039 GO:0001098 basal transcription machinery binding 6/1082 60/18639 0.1 1.72264325323475 0.133768842389733 0.471465010940039 GO:0001099 basal RNA polymerase II transcription machinery binding 6/1082 60/18639 0.1 1.72264325323475 0.133768842389733 0.471465010940039 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 6/1082 60/18639 0.1 1.72264325323475 0.133768842389733 0.471465010940039 GO:0140104 molecular carrier activity 19/1082 249/18639 0.0763052208835341 1.31446673941607 0.13599729379575 0.477649031867999 GO:0003684 damaged DNA binding 7/1082 74/18639 0.0945945945945946 1.62952740170855 0.137135159159463 0.479973057058121 GO:0034061 DNA polymerase activity 4/1082 35/18639 0.114285714285714 1.968735146554 0.143033824976809 0.494484011466819 GO:0043015 gamma-tubulin binding 4/1082 35/18639 0.114285714285714 1.968735146554 0.143033824976809 0.494484011466819 GO:0061631 ubiquitin conjugating enzyme activity 4/1082 35/18639 0.114285714285714 1.968735146554 0.143033824976809 0.494484011466819 GO:0005178 integrin binding 13/1082 161/18639 0.0807453416149068 1.39095417963054 0.143403490200373 0.494484011466819 GO:0044183 protein folding chaperone 7/1082 75/18639 0.0933333333333333 1.60780036968577 0.144184580632679 0.494484011466819 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 5/1082 48/18639 0.104166666666667 1.79442005545287 0.144224503344489 0.494484011466819 GO:0003887 DNA-directed DNA polymerase activity 3/1082 23/18639 0.130434782608696 2.24692598248011 0.146127730253272 0.495948660253529 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/1082 23/18639 0.130434782608696 2.24692598248011 0.146127730253272 0.495948660253529 GO:0016493 C-C chemokine receptor activity 3/1082 23/18639 0.130434782608696 2.24692598248011 0.146127730253272 0.495948660253529 GO:0004875 complement receptor activity 2/1082 12/18639 0.166666666666667 2.87107208872458 0.151237318599151 0.497115661636555 GO:0005049 nuclear export signal receptor activity 2/1082 12/18639 0.166666666666667 2.87107208872458 0.151237318599151 0.497115661636555 GO:0005527 macrolide binding 2/1082 12/18639 0.166666666666667 2.87107208872458 0.151237318599151 0.497115661636555 GO:0010853 cyclase activator activity 2/1082 12/18639 0.166666666666667 2.87107208872458 0.151237318599151 0.497115661636555 GO:0035197 siRNA binding 2/1082 12/18639 0.166666666666667 2.87107208872458 0.151237318599151 0.497115661636555 GO:0035497 cAMP response element binding 2/1082 12/18639 0.166666666666667 2.87107208872458 0.151237318599151 0.497115661636555 GO:0043047 single-stranded telomeric DNA binding 2/1082 12/18639 0.166666666666667 2.87107208872458 0.151237318599151 0.497115661636555 GO:0097371 MDM2/MDM4 family protein binding 2/1082 12/18639 0.166666666666667 2.87107208872458 0.151237318599151 0.497115661636555 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 2/1082 12/18639 0.166666666666667 2.87107208872458 0.151237318599151 0.497115661636555 GO:0017022 myosin binding 7/1082 76/18639 0.0921052631578947 1.58664510166359 0.151403281867483 0.497115661636555 GO:0001222 transcription corepressor binding 5/1082 49/18639 0.102040816326531 1.75779923799464 0.153457145871825 0.502223386489609 GO:0004033 aldo-keto reductase (NADPH) activity 4/1082 36/18639 0.111111111111111 1.91404805914972 0.153999005693154 0.502365688474756 GO:0022804 active transmembrane transporter activity 32/1082 457/18639 0.0700218818380744 1.2062272232716 0.156807303013214 0.509876649797806 GO:0019957 C-C chemokine binding 3/1082 24/18639 0.125 2.15330406654344 0.160225424136957 0.519315844148079 GO:0016779 nucleotidyltransferase activity 11/1082 136/18639 0.0808823529411765 1.3933143959987 0.166881388381447 0.53915525477083 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 2/1082 13/18639 0.153846153846154 2.65022038959192 0.172185713780264 0.542078048102698 GO:0019104 DNA N-glycosylase activity 2/1082 13/18639 0.153846153846154 2.65022038959192 0.172185713780264 0.542078048102698 GO:0019855 calcium channel inhibitor activity 2/1082 13/18639 0.153846153846154 2.65022038959192 0.172185713780264 0.542078048102698 GO:0030955 potassium ion binding 2/1082 13/18639 0.153846153846154 2.65022038959192 0.172185713780264 0.542078048102698 GO:0031432 titin binding 2/1082 13/18639 0.153846153846154 2.65022038959192 0.172185713780264 0.542078048102698 GO:0032396 inhibitory MHC class I receptor activity 2/1082 13/18639 0.153846153846154 2.65022038959192 0.172185713780264 0.542078048102698 GO:0043560 insulin receptor substrate binding 2/1082 13/18639 0.153846153846154 2.65022038959192 0.172185713780264 0.542078048102698 GO:0016922 nuclear receptor binding 11/1082 137/18639 0.0802919708029197 1.38314421792571 0.172609157342907 0.542078048102698 GO:0005048 signal sequence binding 5/1082 51/18639 0.0980392156862745 1.68886593454387 0.172626045080324 0.542078048102698 GO:0019843 rRNA binding 6/1082 65/18639 0.0923076923076923 1.59013223375515 0.174694084348034 0.546868437959063 GO:0043531 ADP binding 4/1082 38/18639 0.105263157894737 1.81330868761553 0.176820345890338 0.551165078371099 GO:0046982 protein heterodimerization activity 26/1082 369/18639 0.0704607046070461 1.21378657409495 0.177909795367375 0.551165078371099 GO:0015631 tubulin binding 27/1082 385/18639 0.0701298701298701 1.2080874762945 0.17873972546849 0.551165078371099 GO:0005085 guanyl-nucleotide exchange factor activity 17/1082 230/18639 0.0739130434782609 1.27325805673873 0.183251925759321 0.551165078371099 GO:0070851 growth factor receptor binding 11/1082 139/18639 0.079136690647482 1.3632428622721 0.184342852659421 0.551165078371099 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 4/1082 39/18639 0.102564102564103 1.76681359306128 0.188636156658449 0.551165078371099 GO:0008198 ferrous iron binding 3/1082 26/18639 0.115384615384615 1.98766529219394 0.189548103471829 0.551165078371099 GO:0019865 immunoglobulin binding 3/1082 26/18639 0.115384615384615 1.98766529219394 0.189548103471829 0.551165078371099 GO:0034237 protein kinase A regulatory subunit binding 3/1082 26/18639 0.115384615384615 1.98766529219394 0.189548103471829 0.551165078371099 GO:0070006 metalloaminopeptidase activity 3/1082 26/18639 0.115384615384615 1.98766529219394 0.189548103471829 0.551165078371099 GO:0070412 R-SMAD binding 3/1082 26/18639 0.115384615384615 1.98766529219394 0.189548103471829 0.551165078371099 GO:0033192 calmodulin-dependent protein phosphatase activity 7/1082 81/18639 0.0864197530864197 1.48870404600534 0.189873327112166 0.551165078371099 GO:0140791 histone H2AXS140 phosphatase activity 7/1082 81/18639 0.0864197530864197 1.48870404600534 0.189873327112166 0.551165078371099 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 7/1082 81/18639 0.0864197530864197 1.48870404600534 0.189873327112166 0.551165078371099 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 7/1082 81/18639 0.0864197530864197 1.48870404600534 0.189873327112166 0.551165078371099 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 7/1082 81/18639 0.0864197530864197 1.48870404600534 0.189873327112166 0.551165078371099 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 7/1082 81/18639 0.0864197530864197 1.48870404600534 0.189873327112166 0.551165078371099 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 7/1082 81/18639 0.0864197530864197 1.48870404600534 0.189873327112166 0.551165078371099 GO:1990439 MAP kinase serine/threonine phosphatase activity 7/1082 81/18639 0.0864197530864197 1.48870404600534 0.189873327112166 0.551165078371099 GO:0005246 calcium channel regulator activity 5/1082 53/18639 0.0943396226415094 1.62513514456109 0.192657163564828 0.551165078371099 GO:0005344 oxygen carrier activity 2/1082 14/18639 0.142857142857143 2.4609189331925 0.193563926332707 0.551165078371099 GO:0005347 ATP transmembrane transporter activity 2/1082 14/18639 0.142857142857143 2.4609189331925 0.193563926332707 0.551165078371099 GO:0008191 metalloendopeptidase inhibitor activity 2/1082 14/18639 0.142857142857143 2.4609189331925 0.193563926332707 0.551165078371099 GO:0008474 palmitoyl-(protein) hydrolase activity 2/1082 14/18639 0.142857142857143 2.4609189331925 0.193563926332707 0.551165078371099 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/1082 14/18639 0.142857142857143 2.4609189331925 0.193563926332707 0.551165078371099 GO:0019763 immunoglobulin receptor activity 2/1082 14/18639 0.142857142857143 2.4609189331925 0.193563926332707 0.551165078371099 GO:0032036 myosin heavy chain binding 2/1082 14/18639 0.142857142857143 2.4609189331925 0.193563926332707 0.551165078371099 GO:0034236 protein kinase A catalytic subunit binding 2/1082 14/18639 0.142857142857143 2.4609189331925 0.193563926332707 0.551165078371099 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 2/1082 14/18639 0.142857142857143 2.4609189331925 0.193563926332707 0.551165078371099 GO:0098599 palmitoyl hydrolase activity 2/1082 14/18639 0.142857142857143 2.4609189331925 0.193563926332707 0.551165078371099 GO:0098847 sequence-specific single stranded DNA binding 2/1082 14/18639 0.142857142857143 2.4609189331925 0.193563926332707 0.551165078371099 GO:1990825 sequence-specific mRNA binding 2/1082 14/18639 0.142857142857143 2.4609189331925 0.193563926332707 0.551165078371099 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 7/1082 82/18639 0.0853658536585366 1.47054911861503 0.198006980470138 0.56064897840983 GO:0033549 MAP kinase phosphatase activity 7/1082 82/18639 0.0853658536585366 1.47054911861503 0.198006980470138 0.56064897840983 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 4/1082 40/18639 0.1 1.72264325323475 0.200694742104798 0.56666750711943 GO:0030145 manganese ion binding 6/1082 68/18639 0.0882352941176471 1.51997934108949 0.201419666367111 0.567125764519686 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 5/1082 54/18639 0.0925925925925926 1.59504004929144 0.202966421220751 0.569889004430409 GO:0004364 glutathione transferase activity 3/1082 27/18639 0.111111111111111 1.91404805914972 0.204687518600274 0.569958615328939 GO:0005044 scavenger receptor activity 3/1082 27/18639 0.111111111111111 1.91404805914972 0.204687518600274 0.569958615328939 GO:0008320 protein transmembrane transporter activity 3/1082 27/18639 0.111111111111111 1.91404805914972 0.204687518600274 0.569958615328939 GO:0140030 modification-dependent protein binding 13/1082 173/18639 0.0751445086705202 1.29447180878912 0.205912305948968 0.571221378030289 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 7/1082 83/18639 0.0843373493975904 1.45283165935461 0.206274386510938 0.571221378030289 GO:0042626 ATPase-coupled transmembrane transporter activity 8/1082 98/18639 0.0816326530612245 1.40623939039571 0.208761269465409 0.576524272934608 GO:0140318 protein transporter activity 4/1082 41/18639 0.0975609756097561 1.68062756413146 0.212975464875739 0.581698720202894 GO:0017018 myosin phosphatase activity 7/1082 84/18639 0.0833333333333333 1.43553604436229 0.214669731437307 0.581698720202894 GO:0000774 adenyl-nucleotide exchange factor activity 2/1082 15/18639 0.133333333333333 2.29685767097967 0.215251609757618 0.581698720202894 GO:0004467 long-chain fatty acid-CoA ligase activity 2/1082 15/18639 0.133333333333333 2.29685767097967 0.215251609757618 0.581698720202894 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/1082 15/18639 0.133333333333333 2.29685767097967 0.215251609757618 0.581698720202894 GO:0005523 tropomyosin binding 2/1082 15/18639 0.133333333333333 2.29685767097967 0.215251609757618 0.581698720202894 GO:0042809 nuclear vitamin D receptor binding 2/1082 15/18639 0.133333333333333 2.29685767097967 0.215251609757618 0.581698720202894 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/1082 15/18639 0.133333333333333 2.29685767097967 0.215251609757618 0.581698720202894 GO:0001221 transcription coregulator binding 9/1082 115/18639 0.0782608695652174 1.34815558948807 0.224196578274283 0.604251740375607 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/1082 29/18639 0.103448275862069 1.7820447447256 0.235715997516966 0.627396445448718 GO:0097472 cyclin-dependent protein kinase activity 3/1082 29/18639 0.103448275862069 1.7820447447256 0.235715997516966 0.627396445448718 GO:0000062 fatty-acyl-CoA binding 2/1082 16/18639 0.125 2.15330406654344 0.23714091836901 0.627396445448718 GO:0005149 interleukin-1 receptor binding 2/1082 16/18639 0.125 2.15330406654344 0.23714091836901 0.627396445448718 GO:0008296 3'-5'-DNA exonuclease activity 2/1082 16/18639 0.125 2.15330406654344 0.23714091836901 0.627396445448718 GO:0017070 U6 snRNA binding 2/1082 16/18639 0.125 2.15330406654344 0.23714091836901 0.627396445448718 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/1082 16/18639 0.125 2.15330406654344 0.23714091836901 0.627396445448718 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4/1082 43/18639 0.0930232558139535 1.60245884021837 0.23812088182193 0.628339918524883 GO:0004722 protein serine/threonine phosphatase activity 8/1082 103/18639 0.0776699029126214 1.33797534231825 0.248449118928087 0.649772505904524 GO:0004521 RNA endonuclease activity 6/1082 73/18639 0.0821917808219178 1.41587116704226 0.24890209696988 0.649772505904524 GO:0043539 protein serine/threonine kinase activator activity 6/1082 73/18639 0.0821917808219178 1.41587116704226 0.24890209696988 0.649772505904524 GO:0030547 signaling receptor inhibitor activity 4/1082 44/18639 0.0909090909090909 1.5660393211225 0.25094467779615 0.649772505904524 GO:0001968 fibronectin binding 3/1082 30/18639 0.1 1.72264325323475 0.251526185316369 0.649772505904524 GO:0008187 poly-pyrimidine tract binding 3/1082 30/18639 0.1 1.72264325323475 0.251526185316369 0.649772505904524 GO:0070566 adenylyltransferase activity 3/1082 30/18639 0.1 1.72264325323475 0.251526185316369 0.649772505904524 GO:0036002 pre-mRNA binding 5/1082 59/18639 0.0847457627118644 1.45986716375826 0.256956115528194 0.649772505904524 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/1082 17/18639 0.117647058823529 2.02663912145265 0.259135463664304 0.649772505904524 GO:0005092 GDP-dissociation inhibitor activity 2/1082 17/18639 0.117647058823529 2.02663912145265 0.259135463664304 0.649772505904524 GO:0016018 cyclosporin A binding 2/1082 17/18639 0.117647058823529 2.02663912145265 0.259135463664304 0.649772505904524 GO:0017110 nucleoside diphosphate phosphatase activity 2/1082 17/18639 0.117647058823529 2.02663912145265 0.259135463664304 0.649772505904524 GO:0030169 low-density lipoprotein particle binding 2/1082 17/18639 0.117647058823529 2.02663912145265 0.259135463664304 0.649772505904524 GO:0038191 neuropilin binding 2/1082 17/18639 0.117647058823529 2.02663912145265 0.259135463664304 0.649772505904524 GO:0045125 bioactive lipid receptor activity 2/1082 17/18639 0.117647058823529 2.02663912145265 0.259135463664304 0.649772505904524 GO:0046965 nuclear retinoid X receptor binding 2/1082 17/18639 0.117647058823529 2.02663912145265 0.259135463664304 0.649772505904524 GO:0051787 misfolded protein binding 2/1082 17/18639 0.117647058823529 2.02663912145265 0.259135463664304 0.649772505904524 GO:0070402 NADPH binding 2/1082 17/18639 0.117647058823529 2.02663912145265 0.259135463664304 0.649772505904524 GO:0070492 oligosaccharide binding 2/1082 17/18639 0.117647058823529 2.02663912145265 0.259135463664304 0.649772505904524 GO:1901567 fatty acid derivative binding 2/1082 17/18639 0.117647058823529 2.02663912145265 0.259135463664304 0.649772505904524 GO:0004715 non-membrane spanning protein tyrosine kinase activity 4/1082 45/18639 0.0888888888888889 1.53123844731978 0.263908974649538 0.660099867113484 GO:0046906 tetrapyrrole binding 11/1082 152/18639 0.0723684210526316 1.24664972273567 0.26854035807128 0.670021487464975 GO:0072341 modified amino acid binding 7/1082 91/18639 0.0769230769230769 1.32511019479596 0.27650660518548 0.680525178469511 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 4/1082 46/18639 0.0869565217391304 1.49795065498674 0.276993991918008 0.680525178469511 GO:0030276 clathrin binding 4/1082 46/18639 0.0869565217391304 1.49795065498674 0.276993991918008 0.680525178469511 GO:0030291 protein serine/threonine kinase inhibitor activity 4/1082 46/18639 0.0869565217391304 1.49795065498674 0.276993991918008 0.680525178469511 GO:0000400 four-way junction DNA binding 2/1082 18/18639 0.111111111111111 1.91404805914972 0.281149349560996 0.680525178469511 GO:0004706 JUN kinase kinase kinase activity 2/1082 18/18639 0.111111111111111 1.91404805914972 0.281149349560996 0.680525178469511 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/1082 18/18639 0.111111111111111 1.91404805914972 0.281149349560996 0.680525178469511 GO:0017075 syntaxin-1 binding 2/1082 18/18639 0.111111111111111 1.91404805914972 0.281149349560996 0.680525178469511 GO:0017128 phospholipid scramblase activity 2/1082 18/18639 0.111111111111111 1.91404805914972 0.281149349560996 0.680525178469511 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/1082 18/18639 0.111111111111111 1.91404805914972 0.281149349560996 0.680525178469511 GO:0098641 cadherin binding involved in cell-cell adhesion 2/1082 18/18639 0.111111111111111 1.91404805914972 0.281149349560996 0.680525178469511 GO:1901611 phosphatidylglycerol binding 2/1082 18/18639 0.111111111111111 1.91404805914972 0.281149349560996 0.680525178469511 GO:0022884 macromolecule transmembrane transporter activity 3/1082 32/18639 0.09375 1.61497804990758 0.28355215769563 0.680525178469511 GO:0043425 bHLH transcription factor binding 3/1082 32/18639 0.09375 1.61497804990758 0.28355215769563 0.680525178469511 GO:0071813 lipoprotein particle binding 3/1082 32/18639 0.09375 1.61497804990758 0.28355215769563 0.680525178469511 GO:0071814 protein-lipid complex binding 3/1082 32/18639 0.09375 1.61497804990758 0.28355215769563 0.680525178469511 GO:0052689 carboxylic ester hydrolase activity 7/1082 92/18639 0.0760869565217391 1.3107068231134 0.285703212130405 0.684058997214842 GO:0051219 phosphoprotein binding 7/1082 93/18639 0.0752688172043011 1.29661320135949 0.294971210541633 0.704575782525985 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/1082 33/18639 0.0909090909090909 1.5660393211225 0.299698159711411 0.705614621523592 GO:0019956 chemokine binding 3/1082 33/18639 0.0909090909090909 1.5660393211225 0.299698159711411 0.705614621523592 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/1082 19/18639 0.105263157894737 1.81330868761553 0.303106280872733 0.705614621523592 GO:0008301 DNA binding, bending 2/1082 19/18639 0.105263157894737 1.81330868761553 0.303106280872733 0.705614621523592 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/1082 19/18639 0.105263157894737 1.81330868761553 0.303106280872733 0.705614621523592 GO:0031420 alkali metal ion binding 2/1082 19/18639 0.105263157894737 1.81330868761553 0.303106280872733 0.705614621523592 GO:0034987 immunoglobulin receptor binding 2/1082 19/18639 0.105263157894737 1.81330868761553 0.303106280872733 0.705614621523592 GO:0042834 peptidoglycan binding 2/1082 19/18639 0.105263157894737 1.81330868761553 0.303106280872733 0.705614621523592 GO:0050145 nucleoside monophosphate kinase activity 2/1082 19/18639 0.105263157894737 1.81330868761553 0.303106280872733 0.705614621523592 GO:0097001 ceramide binding 2/1082 19/18639 0.105263157894737 1.81330868761553 0.303106280872733 0.705614621523592 GO:0120227 acyl-CoA binding 2/1082 19/18639 0.105263157894737 1.81330868761553 0.303106280872733 0.705614621523592 GO:0020037 heme binding 10/1082 142/18639 0.0704225352112676 1.21312905157377 0.310591149602616 0.721372992625431 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 3/1082 34/18639 0.0882352941176471 1.51997934108949 0.315889090579897 0.73199127196445 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/1082 20/18639 0.1 1.72264325323475 0.324938739784744 0.747804223066261 GO:0010851 cyclase regulator activity 2/1082 20/18639 0.1 1.72264325323475 0.324938739784744 0.747804223066261 GO:0030627 pre-mRNA 5'-splice site binding 2/1082 20/18639 0.1 1.72264325323475 0.324938739784744 0.747804223066261 GO:0019955 cytokine binding 10/1082 144/18639 0.0694444444444444 1.19628003696858 0.325928562197217 0.748373555113427 GO:0001618 virus receptor activity 6/1082 81/18639 0.0740740740740741 1.27603203943315 0.330156170064995 0.756357771421625 GO:0140566 histone reader activity 3/1082 35/18639 0.0857142857142857 1.4765513599155 0.332094271730187 0.75907262109757 GO:0035591 signaling adaptor activity 9/1082 129/18639 0.0697674418604651 1.20184413016378 0.333999504168165 0.761700226700249 GO:0140272 exogenous protein binding 6/1082 82/18639 0.0731707317073171 1.2604706730986 0.340589000822484 0.774974521058834 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/1082 21/18639 0.0952380952380952 1.64061262212833 0.346587225449233 0.78331821357136 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/1082 21/18639 0.0952380952380952 1.64061262212833 0.346587225449233 0.78331821357136 GO:0051010 microtubule plus-end binding 2/1082 21/18639 0.0952380952380952 1.64061262212833 0.346587225449233 0.78331821357136 GO:0044390 ubiquitin-like protein conjugating enzyme binding 3/1082 36/18639 0.0833333333333333 1.43553604436229 0.348284750460826 0.783640688536858 GO:0045505 dynein intermediate chain binding 3/1082 36/18639 0.0833333333333333 1.43553604436229 0.348284750460826 0.783640688536858 GO:0001217 DNA-binding transcription repressor activity 18/1082 278/18639 0.0647482014388489 1.11538052367718 0.350431132628315 0.786713990399424 GO:0016853 isomerase activity 12/1082 180/18639 0.0666666666666667 1.14842883548983 0.352908091860597 0.790514125767737 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 4/1082 52/18639 0.0769230769230769 1.32511019479596 0.356986376937888 0.797876425617275 GO:0019787 ubiquitin-like protein transferase activity 30/1082 479/18639 0.0626304801670146 1.07889974106561 0.359521005375373 0.800362367408357 GO:0032934 sterol binding 5/1082 68/18639 0.0735294117647059 1.2666494509079 0.360480669447811 0.800362367408357 GO:0140223 general transcription initiation factor activity 5/1082 68/18639 0.0735294117647059 1.2666494509079 0.360480669447811 0.800362367408357 GO:0022829 wide pore channel activity 3/1082 37/18639 0.0810810810810811 1.39673777289304 0.364433300463713 0.807359927181148 GO:0016881 acid-amino acid ligase activity 2/1082 22/18639 0.0909090909090909 1.5660393211225 0.367999552157954 0.809920411736284 GO:0034062 5'-3' RNA polymerase activity 2/1082 22/18639 0.0909090909090909 1.5660393211225 0.367999552157954 0.809920411736284 GO:0097747 RNA polymerase activity 2/1082 22/18639 0.0909090909090909 1.5660393211225 0.367999552157954 0.809920411736284 GO:0016251 RNA polymerase II general transcription initiation factor activity 4/1082 53/18639 0.0754716981132075 1.30010811564887 0.370401006600996 0.813429661555127 GO:0051020 GTPase binding 20/1082 315/18639 0.0634920634920635 1.09374174808556 0.372024350473476 0.813805069967213 GO:0008080 N-acetyltransferase activity 5/1082 69/18639 0.072463768115942 1.24829221248895 0.372186644102068 0.813805069967213 GO:0050661 NADP binding 4/1082 54/18639 0.0740740740740741 1.27603203943315 0.383795773431415 0.824381523059891 GO:0000295 adenine nucleotide transmembrane transporter activity 2/1082 23/18639 0.0869565217391304 1.49795065498674 0.389130201863163 0.824381523059891 GO:0008171 O-methyltransferase activity 2/1082 23/18639 0.0869565217391304 1.49795065498674 0.389130201863163 0.824381523059891 GO:0016849 phosphorus-oxygen lyase activity 2/1082 23/18639 0.0869565217391304 1.49795065498674 0.389130201863163 0.824381523059891 GO:0017134 fibroblast growth factor binding 2/1082 23/18639 0.0869565217391304 1.49795065498674 0.389130201863163 0.824381523059891 GO:0042171 lysophosphatidic acid acyltransferase activity 2/1082 23/18639 0.0869565217391304 1.49795065498674 0.389130201863163 0.824381523059891 GO:0071617 lysophospholipid acyltransferase activity 2/1082 23/18639 0.0869565217391304 1.49795065498674 0.389130201863163 0.824381523059891 GO:0099186 structural constituent of postsynapse 2/1082 23/18639 0.0869565217391304 1.49795065498674 0.389130201863163 0.824381523059891 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/1082 23/18639 0.0869565217391304 1.49795065498674 0.389130201863163 0.824381523059891 GO:0003774 cytoskeletal motor activity 10/1082 153/18639 0.065359477124183 1.12591062302925 0.396397120884334 0.824381523059891 GO:0000217 DNA secondary structure binding 3/1082 39/18639 0.0769230769230769 1.32511019479596 0.396504265372155 0.824381523059891 GO:0008374 O-acyltransferase activity 4/1082 55/18639 0.0727272727272727 1.252831456898 0.397155818034757 0.824381523059891 GO:0003697 single-stranded DNA binding 8/1082 121/18639 0.0661157024793388 1.13893768808909 0.40492268916197 0.824381523059891 GO:0004540 RNA nuclease activity 8/1082 121/18639 0.0661157024793388 1.13893768808909 0.40492268916197 0.824381523059891 GO:0005315 phosphate transmembrane transporter activity 2/1082 24/18639 0.0833333333333333 1.43553604436229 0.409939727110999 0.824381523059891 GO:0005540 hyaluronic acid binding 2/1082 24/18639 0.0833333333333333 1.43553604436229 0.409939727110999 0.824381523059891 GO:0015149 hexose transmembrane transporter activity 2/1082 24/18639 0.0833333333333333 1.43553604436229 0.409939727110999 0.824381523059891 GO:0050699 WW domain binding 2/1082 24/18639 0.0833333333333333 1.43553604436229 0.409939727110999 0.824381523059891 GO:0055056 D-glucose transmembrane transporter activity 2/1082 24/18639 0.0833333333333333 1.43553604436229 0.409939727110999 0.824381523059891 GO:0070300 phosphatidic acid binding 2/1082 24/18639 0.0833333333333333 1.43553604436229 0.409939727110999 0.824381523059891 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/1082 24/18639 0.0833333333333333 1.43553604436229 0.409939727110999 0.824381523059891 GO:0140597 protein carrier chaperone 12/1082 188/18639 0.0638297872340425 1.09955952334133 0.409962966531665 0.824381523059891 GO:0015144 carbohydrate transmembrane transporter activity 3/1082 40/18639 0.075 1.29198243992606 0.412380713204644 0.824381523059891 GO:0140662 ATP-dependent protein folding chaperone 3/1082 40/18639 0.075 1.29198243992606 0.412380713204644 0.824381523059891 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 6/1082 89/18639 0.0674157303370786 1.16133253027062 0.414104642732272 0.824381523059891 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 6/1082 89/18639 0.0674157303370786 1.16133253027062 0.414104642732272 0.824381523059891 GO:0140793 histone H2AXY142 phosphatase activity 6/1082 90/18639 0.0666666666666667 1.14842883548983 0.424584412461422 0.824381523059891 GO:0042169 SH2 domain binding 3/1082 41/18639 0.0731707317073171 1.2604706730986 0.428123232809558 0.824381523059891 GO:0004709 MAP kinase kinase kinase activity 2/1082 25/18639 0.08 1.3781146025878 0.430394200724611 0.824381523059891 GO:0005251 delayed rectifier potassium channel activity 2/1082 25/18639 0.08 1.3781146025878 0.430394200724611 0.824381523059891 GO:0008139 nuclear localization sequence binding 2/1082 25/18639 0.08 1.3781146025878 0.430394200724611 0.824381523059891 GO:0015645 fatty acid ligase activity 2/1082 25/18639 0.08 1.3781146025878 0.430394200724611 0.824381523059891 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/1082 25/18639 0.08 1.3781146025878 0.430394200724611 0.824381523059891 GO:0017025 TBP-class protein binding 2/1082 25/18639 0.08 1.3781146025878 0.430394200724611 0.824381523059891 GO:0017056 structural constituent of nuclear pore 2/1082 25/18639 0.08 1.3781146025878 0.430394200724611 0.824381523059891 GO:0042974 nuclear retinoic acid receptor binding 2/1082 25/18639 0.08 1.3781146025878 0.430394200724611 0.824381523059891 GO:0047617 fatty acyl-CoA hydrolase activity 2/1082 25/18639 0.08 1.3781146025878 0.430394200724611 0.824381523059891 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/1082 25/18639 0.08 1.3781146025878 0.430394200724611 0.824381523059891 GO:0120020 cholesterol transfer activity 2/1082 25/18639 0.08 1.3781146025878 0.430394200724611 0.824381523059891 GO:0120515 fatty acid-CoA ligase activity 2/1082 25/18639 0.08 1.3781146025878 0.430394200724611 0.824381523059891 GO:0031491 nucleosome binding 5/1082 74/18639 0.0675675675675676 1.16394814407753 0.430510266184139 0.824381523059891 GO:0016755 aminoacyltransferase activity 30/1082 496/18639 0.0604838709677419 1.04192132252102 0.434775303672522 0.824381523059891 GO:0008017 microtubule binding 17/1082 276/18639 0.0615942028985507 1.06104838061561 0.436216436328902 0.824381523059891 GO:0004520 DNA endonuclease activity 3/1082 42/18639 0.0714285714285714 1.23045946659625 0.443712889871245 0.824381523059891 GO:0008307 structural constituent of muscle 3/1082 42/18639 0.0714285714285714 1.23045946659625 0.443712889871245 0.824381523059891 GO:0004879 nuclear receptor activity 4/1082 59/18639 0.0677966101694915 1.16789373100661 0.449975135170005 0.824381523059891 GO:0000182 rDNA binding 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0003796 lysozyme activity 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0004382 GDP phosphatase activity 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0005031 tumor necrosis factor receptor activity 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0005131 growth hormone receptor binding 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0005381 iron ion transmembrane transporter activity 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0008190 eukaryotic initiation factor 4E binding 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0008239 dipeptidyl-peptidase activity 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0015279 store-operated calcium channel activity 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0031419 cobalamin binding 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0031996 thioesterase binding 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0050815 phosphoserine residue binding 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0051880 G-quadruplex DNA binding 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0070097 delta-catenin binding 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0070739 protein-glutamic acid ligase activity 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0070740 tubulin-glutamic acid ligase activity 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0099122 RNA polymerase II C-terminal domain binding 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0140940 histone H2A methyltransferase activity 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0141109 transporter activator activity 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:1990259 histone H2AQ104 methyltransferase activity 1/1082 10/18639 0.1 1.72264325323475 0.450190337812574 0.824381523059891 GO:0004435 phosphatidylinositol phospholipase C activity 2/1082 26/18639 0.0769230769230769 1.32511019479596 0.450464708829009 0.824381523059891 GO:0004529 DNA exonuclease activity 2/1082 26/18639 0.0769230769230769 1.32511019479596 0.450464708829009 0.824381523059891 GO:0005112 Notch binding 2/1082 26/18639 0.0769230769230769 1.32511019479596 0.450464708829009 0.824381523059891 GO:0005160 transforming growth factor beta receptor binding 2/1082 26/18639 0.0769230769230769 1.32511019479596 0.450464708829009 0.824381523059891 GO:0015145 monosaccharide transmembrane transporter activity 2/1082 26/18639 0.0769230769230769 1.32511019479596 0.450464708829009 0.824381523059891 GO:0015216 purine nucleotide transmembrane transporter activity 2/1082 26/18639 0.0769230769230769 1.32511019479596 0.450464708829009 0.824381523059891 GO:0016289 acyl-CoA hydrolase activity 2/1082 26/18639 0.0769230769230769 1.32511019479596 0.450464708829009 0.824381523059891 GO:0043548 phosphatidylinositol 3-kinase binding 2/1082 26/18639 0.0769230769230769 1.32511019479596 0.450464708829009 0.824381523059891 GO:0050681 nuclear androgen receptor binding 2/1082 26/18639 0.0769230769230769 1.32511019479596 0.450464708829009 0.824381523059891 GO:0120014 phospholipid transfer activity 2/1082 26/18639 0.0769230769230769 1.32511019479596 0.450464708829009 0.824381523059891 GO:0051536 iron-sulfur cluster binding 5/1082 76/18639 0.0657894736842105 1.1333179297597 0.453564962797541 0.824381523059891 GO:0004519 endonuclease activity 8/1082 127/18639 0.062992125984252 1.08512960833685 0.458384434574613 0.824381523059891 GO:0019783 ubiquitin-like protein peptidase activity 8/1082 127/18639 0.062992125984252 1.08512960833685 0.458384434574613 0.824381523059891 GO:0042826 histone deacetylase binding 8/1082 127/18639 0.062992125984252 1.08512960833685 0.458384434574613 0.824381523059891 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 14/1082 229/18639 0.0611353711790393 1.05314434695574 0.460298089459176 0.824381523059891 GO:0098531 ligand-modulated transcription factor activity 4/1082 60/18639 0.0666666666666667 1.14842883548983 0.462962290643521 0.824381523059891 GO:0003724 RNA helicase activity 5/1082 77/18639 0.0649350649350649 1.1185995150875 0.464998347563483 0.824381523059891 GO:0051540 metal cluster binding 5/1082 77/18639 0.0649350649350649 1.1185995150875 0.464998347563483 0.824381523059891 GO:0042562 hormone binding 6/1082 94/18639 0.0638297872340425 1.09955952334133 0.46616540201145 0.824381523059891 GO:0008266 poly(U) RNA binding 2/1082 27/18639 0.0740740740740741 1.27603203943315 0.470126884047308 0.824381523059891 GO:0015252 proton channel activity 2/1082 27/18639 0.0740740740740741 1.27603203943315 0.470126884047308 0.824381523059891 GO:0016405 CoA-ligase activity 2/1082 27/18639 0.0740740740740741 1.27603203943315 0.470126884047308 0.824381523059891 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/1082 27/18639 0.0740740740740741 1.27603203943315 0.470126884047308 0.824381523059891 GO:0016790 thiolester hydrolase activity 3/1082 44/18639 0.0681818181818182 1.17452949084188 0.47436553042705 0.824381523059891 GO:0019205 nucleobase-containing compound kinase activity 3/1082 44/18639 0.0681818181818182 1.17452949084188 0.47436553042705 0.824381523059891 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 4/1082 61/18639 0.0655737704918033 1.12960213326869 0.475839773026971 0.824381523059891 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0001851 complement component C3b binding 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0003953 NAD+ nucleosidase activity 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0005114 type II transforming growth factor beta receptor binding 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0005225 volume-sensitive anion channel activity 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0008503 benzodiazepine receptor activity 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0008526 phosphatidylinositol transfer activity 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0019107 myristoyltransferase activity 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0019206 nucleoside kinase activity 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0019215 intermediate filament binding 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0032794 GTPase activating protein binding 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0043522 leucine zipper domain binding 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0070697 activin receptor binding 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0097493 structural molecule activity conferring elasticity 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0140031 phosphorylation-dependent protein binding 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0180030 inositol phosphate kinase activity 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:1990948 ubiquitin ligase inhibitor activity 1/1082 11/18639 0.0909090909090909 1.5660393211225 0.482124099930068 0.824381523059891 GO:0140713 histone chaperone activity 10/1082 164/18639 0.0609756097560976 1.05039222758216 0.483091585131083 0.824381523059891 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 8/1082 130/18639 0.0615384615384615 1.06008815583677 0.484805236541429 0.824381523059891 GO:0004896 cytokine receptor activity 6/1082 96/18639 0.0625 1.07665203327172 0.486664635199971 0.824381523059891 GO:0008186 ATP-dependent activity, acting on RNA 5/1082 79/18639 0.0632911392405063 1.09028054002199 0.487637880602068 0.824381523059891 GO:0016835 carbon-oxygen lyase activity 5/1082 79/18639 0.0632911392405063 1.09028054002199 0.487637880602068 0.824381523059891 GO:0001216 DNA-binding transcription activator activity 29/1082 491/18639 0.0590631364562118 1.01744713531177 0.489275047221292 0.824381523059891 GO:0045499 chemorepellent activity 2/1082 28/18639 0.0714285714285714 1.23045946659625 0.489360475919456 0.824381523059891 GO:0046625 sphingolipid binding 2/1082 28/18639 0.0714285714285714 1.23045946659625 0.489360475919456 0.824381523059891 GO:0051119 sugar transmembrane transporter activity 2/1082 28/18639 0.0714285714285714 1.23045946659625 0.489360475919456 0.824381523059891 GO:0051959 dynein light intermediate chain binding 2/1082 28/18639 0.0714285714285714 1.23045946659625 0.489360475919456 0.824381523059891 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/1082 28/18639 0.0714285714285714 1.23045946659625 0.489360475919456 0.824381523059891 GO:0141052 histone H3 demethylase activity 2/1082 28/18639 0.0714285714285714 1.23045946659625 0.489360475919456 0.824381523059891 GO:0046915 transition metal ion transmembrane transporter activity 3/1082 45/18639 0.0666666666666667 1.14842883548983 0.489398141554016 0.824381523059891 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 16/1082 268/18639 0.0597014925373134 1.02844373327448 0.490887881101977 0.824381523059891 GO:0101005 deubiquitinase activity 7/1082 115/18639 0.0608695652173913 1.04856545849072 0.504393238967554 0.824381523059891 GO:0004725 protein tyrosine phosphatase activity 6/1082 98/18639 0.0612244897959184 1.05467954279679 0.506907752296925 0.824381523059891 GO:0004629 phospholipase C activity 2/1082 29/18639 0.0689655172413793 1.18802982981707 0.508148955801122 0.824381523059891 GO:0106222 lncRNA binding 2/1082 29/18639 0.0689655172413793 1.18802982981707 0.508148955801122 0.824381523059891 GO:0000340 RNA 7-methylguanosine cap binding 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0003720 telomerase activity 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0004000 adenosine deaminase activity 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0004032 aldose reductase (NADPH) activity 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0004526 ribonuclease P activity 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0005165 neurotrophin receptor binding 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0008179 adenylate cyclase binding 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0008603 cAMP-dependent protein kinase regulator activity 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0015166 polyol transmembrane transporter activity 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0016423 tRNA (guanine) methyltransferase activity 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0017166 vinculin binding 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0034452 dynactin binding 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0036009 protein-glutamine N-methyltransferase activity 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0042301 phosphate ion binding 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0070410 co-SMAD binding 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:1990459 transferrin receptor binding 1/1082 12/18639 0.0833333333333333 1.43553604436229 0.512204716414697 0.824381523059891 GO:0004536 DNA nuclease activity 4/1082 64/18639 0.0625 1.07665203327172 0.513716238241596 0.824381523059891 GO:0000510 H3-H4 histone complex chaperone activity 9/1082 151/18639 0.0596026490066225 1.02674101186177 0.516579889822807 0.824381523059891 GO:0140584 chromatin extrusion motor activity 9/1082 151/18639 0.0596026490066225 1.02674101186177 0.516579889822807 0.824381523059891 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 9/1082 151/18639 0.0596026490066225 1.02674101186177 0.516579889822807 0.824381523059891 GO:0140849 ATP-dependent H2AZ histone chaperone activity 9/1082 151/18639 0.0596026490066225 1.02674101186177 0.516579889822807 0.824381523059891 GO:0043495 protein-membrane adaptor activity 3/1082 47/18639 0.0638297872340425 1.09955952334133 0.518810447173481 0.824381523059891 GO:0015616 DNA translocase activity 9/1082 152/18639 0.0592105263157895 1.01998613678373 0.524641170567277 0.824381523059891 GO:0140674 ATP-dependent histone chaperone activity 9/1082 152/18639 0.0592105263157895 1.01998613678373 0.524641170567277 0.824381523059891 GO:0120013 lipid transfer activity 4/1082 65/18639 0.0615384615384615 1.06008815583677 0.52606034420652 0.824381523059891 GO:0160215 deacylase activity 4/1082 65/18639 0.0615384615384615 1.06008815583677 0.52606034420652 0.824381523059891 GO:0001965 G-protein alpha-subunit binding 2/1082 30/18639 0.0666666666666667 1.14842883548983 0.526479153692889 0.824381523059891 GO:0015215 nucleotide transmembrane transporter activity 2/1082 30/18639 0.0666666666666667 1.14842883548983 0.526479153692889 0.824381523059891 GO:0016769 transferase activity, transferring nitrogenous groups 2/1082 30/18639 0.0666666666666667 1.14842883548983 0.526479153692889 0.824381523059891 GO:0031624 ubiquitin conjugating enzyme binding 2/1082 30/18639 0.0666666666666667 1.14842883548983 0.526479153692889 0.824381523059891 GO:0032452 histone demethylase activity 2/1082 30/18639 0.0666666666666667 1.14842883548983 0.526479153692889 0.824381523059891 GO:0033612 receptor serine/threonine kinase binding 2/1082 30/18639 0.0666666666666667 1.14842883548983 0.526479153692889 0.824381523059891 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/1082 30/18639 0.0666666666666667 1.14842883548983 0.526479153692889 0.824381523059891 GO:0048019 receptor antagonist activity 2/1082 30/18639 0.0666666666666667 1.14842883548983 0.526479153692889 0.824381523059891 GO:0098918 structural constituent of synapse 2/1082 30/18639 0.0666666666666667 1.14842883548983 0.526479153692889 0.824381523059891 GO:0061775 cohesin loader activity 9/1082 153/18639 0.0588235294117647 1.01331956072632 0.532656423672461 0.824381523059891 GO:0140693 molecular condensate scaffold activity 3/1082 48/18639 0.0625 1.07665203327172 0.533167873903348 0.824381523059891 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 28/1082 484/18639 0.0578512396694215 0.996570477077955 0.535891518193072 0.824381523059891 GO:0140789 histone phosphatase activity 8/1082 136/18639 0.0588235294117647 1.01331956072632 0.536507415675197 0.824381523059891 GO:0008235 metalloexopeptidase activity 4/1082 66/18639 0.0606060606060606 1.04402621408167 0.538250651041559 0.824381523059891 GO:0003964 RNA-directed DNA polymerase activity 1/1082 13/18639 0.0769230769230769 1.32511019479596 0.5405396333009 0.824381523059891 GO:0005035 death receptor activity 1/1082 13/18639 0.0769230769230769 1.32511019479596 0.5405396333009 0.824381523059891 GO:0005172 vascular endothelial growth factor receptor binding 1/1082 13/18639 0.0769230769230769 1.32511019479596 0.5405396333009 0.824381523059891 GO:0008035 high-density lipoprotein particle binding 1/1082 13/18639 0.0769230769230769 1.32511019479596 0.5405396333009 0.824381523059891 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/1082 13/18639 0.0769230769230769 1.32511019479596 0.5405396333009 0.824381523059891 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1082 13/18639 0.0769230769230769 1.32511019479596 0.5405396333009 0.824381523059891 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/1082 13/18639 0.0769230769230769 1.32511019479596 0.5405396333009 0.824381523059891 GO:0046975 histone H3K36 methyltransferase activity 1/1082 13/18639 0.0769230769230769 1.32511019479596 0.5405396333009 0.824381523059891 GO:0051011 microtubule minus-end binding 1/1082 13/18639 0.0769230769230769 1.32511019479596 0.5405396333009 0.824381523059891 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/1082 13/18639 0.0769230769230769 1.32511019479596 0.5405396333009 0.824381523059891 GO:0070700 BMP receptor binding 1/1082 13/18639 0.0769230769230769 1.32511019479596 0.5405396333009 0.824381523059891 GO:0140666 annealing activity 1/1082 13/18639 0.0769230769230769 1.32511019479596 0.5405396333009 0.824381523059891 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1082 13/18639 0.0769230769230769 1.32511019479596 0.5405396333009 0.824381523059891 GO:0140852 histone ubiquitin ligase activity 1/1082 13/18639 0.0769230769230769 1.32511019479596 0.5405396333009 0.824381523059891 GO:0008327 methyl-CpG binding 2/1082 31/18639 0.0645161290322581 1.11138274402242 0.544340924629355 0.824381523059891 GO:0016411 acylglycerol O-acyltransferase activity 2/1082 31/18639 0.0645161290322581 1.11138274402242 0.544340924629355 0.824381523059891 GO:0016878 acid-thiol ligase activity 2/1082 31/18639 0.0645161290322581 1.11138274402242 0.544340924629355 0.824381523059891 GO:0047499 calcium-independent phospholipase A2 activity 2/1082 31/18639 0.0645161290322581 1.11138274402242 0.544340924629355 0.824381523059891 GO:0070273 phosphatidylinositol-4-phosphate binding 2/1082 31/18639 0.0645161290322581 1.11138274402242 0.544340924629355 0.824381523059891 GO:0140457 protein demethylase activity 2/1082 31/18639 0.0645161290322581 1.11138274402242 0.544340924629355 0.824381523059891 GO:0005539 glycosaminoglycan binding 14/1082 242/18639 0.0578512396694215 0.996570477077955 0.544680649164571 0.824381523059891 GO:0030695 GTPase regulator activity 28/1082 489/18639 0.0572597137014315 0.986380594899244 0.558409107576486 0.835458535266083 GO:0031369 translation initiation factor binding 2/1082 32/18639 0.0625 1.07665203327172 0.561726842424936 0.835458535266083 GO:0042910 xenobiotic transmembrane transporter activity 2/1082 32/18639 0.0625 1.07665203327172 0.561726842424936 0.835458535266083 GO:0120015 sterol transfer activity 2/1082 32/18639 0.0625 1.07665203327172 0.561726842424936 0.835458535266083 GO:0140142 nucleocytoplasmic carrier activity 2/1082 32/18639 0.0625 1.07665203327172 0.561726842424936 0.835458535266083 GO:0005548 phospholipid transporter activity 4/1082 68/18639 0.0588235294117647 1.01331956072632 0.562142687355234 0.835458535266083 GO:0060589 nucleoside-triphosphatase regulator activity 28/1082 490/18639 0.0571428571428571 0.984367573277 0.562874067663409 0.835458535266083 GO:0005161 platelet-derived growth factor receptor binding 1/1082 14/18639 0.0714285714285714 1.23045946659625 0.567230072298453 0.835458535266083 GO:0005545 1-phosphatidylinositol binding 1/1082 14/18639 0.0714285714285714 1.23045946659625 0.567230072298453 0.835458535266083 GO:0008494 translation activator activity 1/1082 14/18639 0.0714285714285714 1.23045946659625 0.567230072298453 0.835458535266083 GO:0031404 chloride ion binding 1/1082 14/18639 0.0714285714285714 1.23045946659625 0.567230072298453 0.835458535266083 GO:0043176 amine binding 1/1082 14/18639 0.0714285714285714 1.23045946659625 0.567230072298453 0.835458535266083 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/1082 14/18639 0.0714285714285714 1.23045946659625 0.567230072298453 0.835458535266083 GO:0061665 SUMO ligase activity 1/1082 14/18639 0.0714285714285714 1.23045946659625 0.567230072298453 0.835458535266083 GO:0061783 peptidoglycan muralytic activity 1/1082 14/18639 0.0714285714285714 1.23045946659625 0.567230072298453 0.835458535266083 GO:0070742 C2H2 zinc finger domain binding 1/1082 14/18639 0.0714285714285714 1.23045946659625 0.567230072298453 0.835458535266083 GO:0071933 Arp2/3 complex binding 1/1082 14/18639 0.0714285714285714 1.23045946659625 0.567230072298453 0.835458535266083 GO:1901612 cardiolipin binding 1/1082 14/18639 0.0714285714285714 1.23045946659625 0.567230072298453 0.835458535266083 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 7/1082 122/18639 0.0573770491803279 0.988401866610103 0.56774711969967 0.835458535266083 GO:0140658 ATP-dependent chromatin remodeler activity 9/1082 158/18639 0.0569620253164557 0.981252486019795 0.571952462951127 0.840419945560839 GO:0071889 14-3-3 protein binding 2/1082 33/18639 0.0606060606060606 1.04402621408167 0.578631918729035 0.848997051060943 GO:0140097 catalytic activity, acting on DNA 19/1082 336/18639 0.056547619047619 0.974113744388698 0.581016571325648 0.850584561509659 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/1082 70/18639 0.0571428571428571 0.984367573277 0.585343804640891 0.850584561509659 GO:0003689 DNA clamp loader activity 9/1082 160/18639 0.05625 0.968986829944547 0.587262699128873 0.850584561509659 GO:0005080 protein kinase C binding 3/1082 52/18639 0.0576923076923077 0.993832646096971 0.588068602654448 0.850584561509659 GO:0015116 sulfate transmembrane transporter activity 1/1082 15/18639 0.0666666666666667 1.14842883548983 0.59237139105137 0.850584561509659 GO:0015250 water channel activity 1/1082 15/18639 0.0666666666666667 1.14842883548983 0.59237139105137 0.850584561509659 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1082 15/18639 0.0666666666666667 1.14842883548983 0.59237139105137 0.850584561509659 GO:0015929 hexosaminidase activity 1/1082 15/18639 0.0666666666666667 1.14842883548983 0.59237139105137 0.850584561509659 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/1082 15/18639 0.0666666666666667 1.14842883548983 0.59237139105137 0.850584561509659 GO:0033130 acetylcholine receptor binding 1/1082 15/18639 0.0666666666666667 1.14842883548983 0.59237139105137 0.850584561509659 GO:0047372 monoacylglycerol lipase activity 1/1082 15/18639 0.0666666666666667 1.14842883548983 0.59237139105137 0.850584561509659 GO:0061578 K63-linked deubiquitinase activity 1/1082 15/18639 0.0666666666666667 1.14842883548983 0.59237139105137 0.850584561509659 GO:0120283 protein serine/threonine kinase binding 1/1082 15/18639 0.0666666666666667 1.14842883548983 0.59237139105137 0.850584561509659 GO:0141050 histone H3K deacetylase activity 1/1082 15/18639 0.0666666666666667 1.14842883548983 0.59237139105137 0.850584561509659 GO:0141051 histone H4K deacetylase activity 1/1082 15/18639 0.0666666666666667 1.14842883548983 0.59237139105137 0.850584561509659 GO:0051427 hormone receptor binding 2/1082 34/18639 0.0588235294117647 1.01331956072632 0.595053345488356 0.85322015967605 GO:0016860 intramolecular oxidoreductase activity 3/1082 53/18639 0.0566037735849057 0.975081086736651 0.601128658417655 0.858268679440505 GO:0034212 protein N-acetyltransferase activity 3/1082 53/18639 0.0566037735849057 0.975081086736651 0.601128658417655 0.858268679440505 GO:0051018 protein kinase A binding 3/1082 53/18639 0.0566037735849057 0.975081086736651 0.601128658417655 0.858268679440505 GO:0004623 phospholipase A2 activity 2/1082 35/18639 0.0571428571428571 0.984367573277 0.610990259049457 0.871114824783384 GO:0015485 cholesterol binding 3/1082 54/18639 0.0555555555555556 0.957024029574861 0.613912945769787 0.872165519584319 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/1082 16/18639 0.0625 1.07665203327172 0.616053422563527 0.872165519584319 GO:0005159 insulin-like growth factor receptor binding 1/1082 16/18639 0.0625 1.07665203327172 0.616053422563527 0.872165519584319 GO:0016722 oxidoreductase activity, acting on metal ions 1/1082 16/18639 0.0625 1.07665203327172 0.616053422563527 0.872165519584319 GO:0030275 LRR domain binding 1/1082 16/18639 0.0625 1.07665203327172 0.616053422563527 0.872165519584319 GO:0016829 lyase activity 11/1082 200/18639 0.055 0.947453789279113 0.616955655461581 0.872217813050875 GO:0043178 alcohol binding 5/1082 92/18639 0.0543478260869565 0.936219159366712 0.624178993969053 0.880690477621531 GO:0098632 cell-cell adhesion mediator activity 3/1082 55/18639 0.0545454545454545 0.9396235926735 0.626418164677577 0.880690477621531 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/1082 36/18639 0.0555555555555556 0.957024029574861 0.626443524260553 0.880690477621531 GO:0016409 palmitoyltransferase activity 2/1082 36/18639 0.0555555555555556 0.957024029574861 0.626443524260553 0.880690477621531 GO:0035064 methylated histone binding 4/1082 74/18639 0.0540540540540541 0.931158515262027 0.629523034780199 0.8814625771982 GO:0016298 lipase activity 7/1082 130/18639 0.0538461538461538 0.927577136357173 0.635192180293861 0.8814625771982 GO:0016798 hydrolase activity, acting on glycosyl bonds 7/1082 130/18639 0.0538461538461538 0.927577136357173 0.635192180293861 0.8814625771982 GO:0004549 tRNA-specific ribonuclease activity 1/1082 17/18639 0.0588235294117647 1.01331956072632 0.638360794994728 0.8814625771982 GO:0004550 nucleoside diphosphate kinase activity 1/1082 17/18639 0.0588235294117647 1.01331956072632 0.638360794994728 0.8814625771982 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/1082 17/18639 0.0588235294117647 1.01331956072632 0.638360794994728 0.8814625771982 GO:0016805 dipeptidase activity 1/1082 17/18639 0.0588235294117647 1.01331956072632 0.638360794994728 0.8814625771982 GO:0030548 acetylcholine receptor regulator activity 1/1082 17/18639 0.0588235294117647 1.01331956072632 0.638360794994728 0.8814625771982 GO:0031489 myosin V binding 1/1082 17/18639 0.0588235294117647 1.01331956072632 0.638360794994728 0.8814625771982 GO:0032183 SUMO binding 1/1082 17/18639 0.0588235294117647 1.01331956072632 0.638360794994728 0.8814625771982 GO:0032977 membrane insertase activity 1/1082 17/18639 0.0588235294117647 1.01331956072632 0.638360794994728 0.8814625771982 GO:0036041 long-chain fatty acid binding 1/1082 17/18639 0.0588235294117647 1.01331956072632 0.638360794994728 0.8814625771982 GO:0070403 NAD+ binding 1/1082 17/18639 0.0588235294117647 1.01331956072632 0.638360794994728 0.8814625771982 GO:0019213 deacetylase activity 2/1082 37/18639 0.0540540540540541 0.931158515262027 0.641415537048944 0.883260739542809 GO:0043394 proteoglycan binding 2/1082 37/18639 0.0540540540540541 0.931158515262027 0.641415537048944 0.883260739542809 GO:0016410 N-acyltransferase activity 5/1082 94/18639 0.0531914893617021 0.916299602784442 0.643158591399574 0.884452742333929 GO:0140034 methylation-dependent protein binding 4/1082 76/18639 0.0526315789473684 0.906654343807763 0.650446151489743 0.887380799499479 GO:0005179 hormone activity 7/1082 132/18639 0.053030303030303 0.913522937321459 0.651082280702891 0.887380799499479 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 7/1082 132/18639 0.053030303030303 0.913522937321459 0.651082280702891 0.887380799499479 GO:0008276 protein methyltransferase activity 5/1082 95/18639 0.0526315789473684 0.906654343807763 0.652420497969873 0.887380799499479 GO:0000146 microfilament motor activity 2/1082 38/18639 0.0526315789473684 0.906654343807763 0.655910044059679 0.887380799499479 GO:0000900 mRNA regulatory element binding translation repressor activity 1/1082 18/18639 0.0555555555555556 0.957024029574861 0.659373232961419 0.887380799499479 GO:0005372 water transmembrane transporter activity 1/1082 18/18639 0.0555555555555556 0.957024029574861 0.659373232961419 0.887380799499479 GO:0008308 voltage-gated monoatomic anion channel activity 1/1082 18/18639 0.0555555555555556 0.957024029574861 0.659373232961419 0.887380799499479 GO:0008525 phosphatidylcholine transporter activity 1/1082 18/18639 0.0555555555555556 0.957024029574861 0.659373232961419 0.887380799499479 GO:0015172 acidic amino acid transmembrane transporter activity 1/1082 18/18639 0.0555555555555556 0.957024029574861 0.659373232961419 0.887380799499479 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/1082 18/18639 0.0555555555555556 0.957024029574861 0.659373232961419 0.887380799499479 GO:0031690 adrenergic receptor binding 1/1082 18/18639 0.0555555555555556 0.957024029574861 0.659373232961419 0.887380799499479 GO:0034185 apolipoprotein binding 1/1082 18/18639 0.0555555555555556 0.957024029574861 0.659373232961419 0.887380799499479 GO:0035615 clathrin adaptor activity 1/1082 18/18639 0.0555555555555556 0.957024029574861 0.659373232961419 0.887380799499479 GO:0070064 proline-rich region binding 1/1082 18/18639 0.0555555555555556 0.957024029574861 0.659373232961419 0.887380799499479 GO:0099602 neurotransmitter receptor regulator activity 1/1082 18/18639 0.0555555555555556 0.957024029574861 0.659373232961419 0.887380799499479 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/1082 39/18639 0.0512820512820513 0.883406796530641 0.669931978042789 0.900388578489508 GO:0015459 potassium channel regulator activity 3/1082 59/18639 0.0508474576271186 0.875920298254958 0.673609378634257 0.9021183115896 GO:0070063 RNA polymerase binding 3/1082 59/18639 0.0508474576271186 0.875920298254958 0.673609378634257 0.9021183115896 GO:0004518 nuclease activity 11/1082 209/18639 0.0526315789473684 0.906654343807763 0.674302086022915 0.9021183115896 GO:0005506 iron ion binding 8/1082 154/18639 0.051948051948052 0.89487961207 0.676856382486785 0.9021183115896 GO:0005520 insulin-like growth factor binding 1/1082 19/18639 0.0526315789473684 0.906654343807763 0.67916584141079 0.9021183115896 GO:0015245 fatty acid transmembrane transporter activity 1/1082 19/18639 0.0526315789473684 0.906654343807763 0.67916584141079 0.9021183115896 GO:0140036 ubiquitin-modified protein reader activity 1/1082 19/18639 0.0526315789473684 0.906654343807763 0.67916584141079 0.9021183115896 GO:0031267 small GTPase binding 15/1082 283/18639 0.0530035335689046 0.913061795000751 0.679230771068988 0.9021183115896 GO:0008170 N-methyltransferase activity 5/1082 98/18639 0.0510204081632653 0.878899618997322 0.67927360961955 0.9021183115896 GO:0019838 growth factor binding 7/1082 136/18639 0.0514705882352941 0.886654615635533 0.681598806237063 0.904015258798631 GO:0032451 demethylase activity 2/1082 40/18639 0.05 0.861321626617375 0.683487307771112 0.904606819320616 GO:0004386 helicase activity 8/1082 155/18639 0.0516129032258065 0.889106195217936 0.68383967889118 0.904606819320616 GO:0000049 tRNA binding 4/1082 80/18639 0.05 0.861321626617375 0.689875625736746 0.911395322074233 GO:0004842 ubiquitin-protein transferase activity 24/1082 449/18639 0.0534521158129176 0.92078926676245 0.692433066520334 0.913047070782724 GO:0004721 phosphoprotein phosphatase activity 9/1082 175/18639 0.0514285714285714 0.8859308159493 0.692937509076174 0.913047070782724 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/1082 41/18639 0.0487804878048781 0.840313782065732 0.696582901358884 0.913495906571326 GO:0001614 purinergic nucleotide receptor activity 1/1082 20/18639 0.05 0.861321626617375 0.697809373075319 0.913495906571326 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/1082 20/18639 0.05 0.861321626617375 0.697809373075319 0.913495906571326 GO:0016502 nucleotide receptor activity 1/1082 20/18639 0.05 0.861321626617375 0.697809373075319 0.913495906571326 GO:0052745 inositol phosphate phosphatase activity 1/1082 20/18639 0.05 0.861321626617375 0.697809373075319 0.913495906571326 GO:0030971 receptor tyrosine kinase binding 4/1082 81/18639 0.0493827160493827 0.850688026288766 0.699223640571653 0.91416009039718 GO:0004674 protein serine/threonine kinase activity 23/1082 433/18639 0.0531177829099307 0.915029903565803 0.700998351387233 0.915293184194729 GO:0019894 kinesin binding 2/1082 42/18639 0.0476190476190476 0.820306311064167 0.709226401933266 0.91859037490481 GO:0031492 nucleosomal DNA binding 2/1082 42/18639 0.0476190476190476 0.820306311064167 0.709226401933266 0.91859037490481 GO:0043175 RNA polymerase core enzyme binding 2/1082 42/18639 0.0476190476190476 0.820306311064167 0.709226401933266 0.91859037490481 GO:0016887 ATP hydrolysis activity 22/1082 417/18639 0.052757793764988 0.90882857484807 0.709856008017115 0.91859037490481 GO:0005319 lipid transporter activity 9/1082 178/18639 0.050561797752809 0.870999397702964 0.71190323280625 0.91859037490481 GO:0001846 opsonin binding 1/1082 21/18639 0.0476190476190476 0.820306311064167 0.715370480456623 0.91859037490481 GO:0005123 death receptor binding 1/1082 21/18639 0.0476190476190476 0.820306311064167 0.715370480456623 0.91859037490481 GO:0010314 phosphatidylinositol-5-phosphate binding 1/1082 21/18639 0.0476190476190476 0.820306311064167 0.715370480456623 0.91859037490481 GO:0035613 RNA stem-loop binding 1/1082 21/18639 0.0476190476190476 0.820306311064167 0.715370480456623 0.91859037490481 GO:0051428 peptide hormone receptor binding 1/1082 21/18639 0.0476190476190476 0.820306311064167 0.715370480456623 0.91859037490481 GO:0061891 calcium ion sensor activity 1/1082 21/18639 0.0476190476190476 0.820306311064167 0.715370480456623 0.91859037490481 GO:0070182 DNA polymerase binding 1/1082 21/18639 0.0476190476190476 0.820306311064167 0.715370480456623 0.91859037490481 GO:0140312 cargo adaptor activity 1/1082 21/18639 0.0476190476190476 0.820306311064167 0.715370480456623 0.91859037490481 GO:0004407 histone deacetylase activity 1/1082 22/18639 0.0454545454545455 0.78301966056125 0.73191195323275 0.929630731634368 GO:0008649 rRNA methyltransferase activity 1/1082 22/18639 0.0454545454545455 0.78301966056125 0.73191195323275 0.929630731634368 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/1082 22/18639 0.0454545454545455 0.78301966056125 0.73191195323275 0.929630731634368 GO:0031683 G-protein beta/gamma-subunit complex binding 1/1082 22/18639 0.0454545454545455 0.78301966056125 0.73191195323275 0.929630731634368 GO:0033558 protein lysine deacetylase activity 1/1082 22/18639 0.0454545454545455 0.78301966056125 0.73191195323275 0.929630731634368 GO:0046972 histone H4K16 acetyltransferase activity 1/1082 22/18639 0.0454545454545455 0.78301966056125 0.73191195323275 0.929630731634368 GO:0140035 ubiquitin-like protein reader activity 1/1082 22/18639 0.0454545454545455 0.78301966056125 0.73191195323275 0.929630731634368 GO:0140784 metal ion sensor activity 1/1082 22/18639 0.0454545454545455 0.78301966056125 0.73191195323275 0.929630731634368 GO:0001223 transcription coactivator binding 2/1082 44/18639 0.0454545454545455 0.78301966056125 0.733190904414011 0.929630731634368 GO:0043014 alpha-tubulin binding 2/1082 44/18639 0.0454545454545455 0.78301966056125 0.733190904414011 0.929630731634368 GO:0140098 catalytic activity, acting on RNA 20/1082 387/18639 0.0516795865633075 0.890254911232429 0.736741224161966 0.9329587361247 GO:0051539 4 iron, 4 sulfur cluster binding 2/1082 45/18639 0.0444444444444444 0.765619223659889 0.744530102686568 0.936003405141716 GO:0140303 intramembrane lipid transporter activity 2/1082 45/18639 0.0444444444444444 0.765619223659889 0.744530102686568 0.936003405141716 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/1082 23/18639 0.0434782608695652 0.74897532749337 0.747492941931368 0.936003405141716 GO:0005158 insulin receptor binding 1/1082 23/18639 0.0434782608695652 0.74897532749337 0.747492941931368 0.936003405141716 GO:0005212 structural constituent of eye lens 1/1082 23/18639 0.0434782608695652 0.74897532749337 0.747492941931368 0.936003405141716 GO:0031681 G-protein beta-subunit binding 1/1082 23/18639 0.0434782608695652 0.74897532749337 0.747492941931368 0.936003405141716 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1082 23/18639 0.0434782608695652 0.74897532749337 0.747492941931368 0.936003405141716 GO:0140102 catalytic activity, acting on a rRNA 1/1082 23/18639 0.0434782608695652 0.74897532749337 0.747492941931368 0.936003405141716 GO:0008237 metallopeptidase activity 9/1082 184/18639 0.0489130434782609 0.842597243430041 0.747502719384009 0.936003405141716 GO:0008081 phosphoric diester hydrolase activity 4/1082 87/18639 0.0459770114942529 0.792019886544713 0.751038469061073 0.936910392697548 GO:0042054 histone methyltransferase activity 3/1082 67/18639 0.0447761194029851 0.771332799955858 0.75445984808437 0.936910392697548 GO:0050840 extracellular matrix binding 3/1082 67/18639 0.0447761194029851 0.771332799955858 0.75445984808437 0.936910392697548 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/1082 46/18639 0.0434782608695652 0.74897532749337 0.755453423912564 0.936910392697548 GO:0004843 cysteine-type deubiquitinase activity 5/1082 108/18639 0.0462962962962963 0.797520024645718 0.758440467598915 0.936910392697548 GO:0005496 steroid binding 5/1082 108/18639 0.0462962962962963 0.797520024645718 0.758440467598915 0.936910392697548 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/1082 24/18639 0.0416666666666667 0.717768022181146 0.762169168662688 0.936910392697548 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/1082 24/18639 0.0416666666666667 0.717768022181146 0.762169168662688 0.936910392697548 GO:0004806 triacylglycerol lipase activity 1/1082 24/18639 0.0416666666666667 0.717768022181146 0.762169168662688 0.936910392697548 GO:0015295 solute:proton symporter activity 1/1082 24/18639 0.0416666666666667 0.717768022181146 0.762169168662688 0.936910392697548 GO:0030215 semaphorin receptor binding 1/1082 24/18639 0.0416666666666667 0.717768022181146 0.762169168662688 0.936910392697548 GO:0030552 cAMP binding 1/1082 24/18639 0.0416666666666667 0.717768022181146 0.762169168662688 0.936910392697548 GO:0043998 histone H2A acetyltransferase activity 1/1082 24/18639 0.0416666666666667 0.717768022181146 0.762169168662688 0.936910392697548 GO:0050431 transforming growth factor beta binding 1/1082 24/18639 0.0416666666666667 0.717768022181146 0.762169168662688 0.936910392697548 GO:0070840 dynein complex binding 1/1082 24/18639 0.0416666666666667 0.717768022181146 0.762169168662688 0.936910392697548 GO:0061733 protein-lysine-acetyltransferase activity 2/1082 47/18639 0.0425531914893617 0.733039682227553 0.765970889545412 0.938151466174697 GO:0140359 ABC-type transporter activity 2/1082 47/18639 0.0425531914893617 0.733039682227553 0.765970889545412 0.938151466174697 GO:0140938 histone H3 methyltransferase activity 2/1082 47/18639 0.0425531914893617 0.733039682227553 0.765970889545412 0.938151466174697 GO:0005516 calmodulin binding 10/1082 207/18639 0.0483091787439614 0.832194808325966 0.768342803531055 0.939914497523427 GO:0001848 complement binding 1/1082 25/18639 0.04 0.6890573012939 0.775993125660108 0.943645024155611 GO:0003707 nuclear steroid receptor activity 1/1082 25/18639 0.04 0.6890573012939 0.775993125660108 0.943645024155611 GO:0015271 outward rectifier potassium channel activity 1/1082 25/18639 0.04 0.6890573012939 0.775993125660108 0.943645024155611 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/1082 48/18639 0.0416666666666667 0.717768022181146 0.776092759790719 0.943645024155611 GO:0032266 phosphatidylinositol-3-phosphate binding 2/1082 48/18639 0.0416666666666667 0.717768022181146 0.776092759790719 0.943645024155611 GO:0042393 histone binding 12/1082 247/18639 0.048582995951417 0.836911701976397 0.777009295683687 0.943645024155611 GO:0008094 ATP-dependent activity, acting on DNA 10/1082 210/18639 0.0476190476190476 0.820306311064167 0.783282550199248 0.947945621492275 GO:0008201 heparin binding 8/1082 172/18639 0.0465116279069767 0.801229420109186 0.787692499186462 0.947945621492275 GO:0140299 molecular sensor activity 3/1082 71/18639 0.0422535211267606 0.727877430944261 0.788406770487223 0.947945621492275 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/1082 26/18639 0.0384615384615385 0.662555097397981 0.789014262333352 0.947945621492275 GO:0008143 poly(A) binding 1/1082 26/18639 0.0384615384615385 0.662555097397981 0.789014262333352 0.947945621492275 GO:0030247 polysaccharide binding 1/1082 26/18639 0.0384615384615385 0.662555097397981 0.789014262333352 0.947945621492275 GO:0030507 spectrin binding 1/1082 26/18639 0.0384615384615385 0.662555097397981 0.789014262333352 0.947945621492275 GO:0050750 low-density lipoprotein particle receptor binding 1/1082 26/18639 0.0384615384615385 0.662555097397981 0.789014262333352 0.947945621492275 GO:0097602 cullin family protein binding 1/1082 26/18639 0.0384615384615385 0.662555097397981 0.789014262333352 0.947945621492275 GO:0015605 organophosphate ester transmembrane transporter activity 2/1082 50/18639 0.04 0.6890573012939 0.795191586541748 0.954229903850098 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/1082 27/18639 0.037037037037037 0.638016019716574 0.8012791614982 0.959251062696182 GO:0008395 steroid hydroxylase activity 1/1082 27/18639 0.037037037037037 0.638016019716574 0.8012791614982 0.959251062696182 GO:0016830 carbon-carbon lyase activity 2/1082 51/18639 0.0392156862745098 0.675546373817549 0.804189735552179 0.959667585791664 GO:0035401 histone H3Y41 kinase activity 5/1082 115/18639 0.0434782608695652 0.74897532749337 0.804483244041623 0.959667585791664 GO:0140801 histone H2AXY142 kinase activity 5/1082 115/18639 0.0434782608695652 0.74897532749337 0.804483244041623 0.959667585791664 GO:0016791 phosphatase activity 13/1082 273/18639 0.0476190476190476 0.820306311064167 0.806432814329302 0.96085611920087 GO:0046875 ephrin receptor binding 1/1082 28/18639 0.0357142857142857 0.615229733298125 0.812831705408524 0.966199596126219 GO:0030159 signaling receptor complex adaptor activity 2/1082 52/18639 0.0384615384615385 0.662555097397981 0.812834580868089 0.966199596126219 GO:1901681 sulfur compound binding 13/1082 275/18639 0.0472727272727273 0.8143404469837 0.814310269642132 0.966813606359563 GO:1990782 protein tyrosine kinase binding 5/1082 117/18639 0.0427350427350427 0.736172330442201 0.816282229229069 0.968014690662237 GO:0061659 ubiquitin-like protein ligase activity 18/1082 372/18639 0.0483870967741935 0.833537058016815 0.819364042759412 0.969980067801003 GO:0017046 peptide hormone binding 2/1082 53/18639 0.0377358490566038 0.650054057824434 0.821136773905361 0.969980067801003 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/1082 53/18639 0.0377358490566038 0.650054057824434 0.821136773905361 0.969980067801003 GO:0004181 metallocarboxypeptidase activity 1/1082 29/18639 0.0344827586206897 0.594014914908535 0.823713232180217 0.969980067801003 GO:0043236 laminin binding 1/1082 29/18639 0.0344827586206897 0.594014914908535 0.823713232180217 0.969980067801003 GO:0051861 glycolipid binding 1/1082 29/18639 0.0344827586206897 0.594014914908535 0.823713232180217 0.969980067801003 GO:0098631 cell adhesion mediator activity 3/1082 76/18639 0.0394736842105263 0.679990757855823 0.825263909397656 0.970672136141001 GO:0043995 histone H4K5 acetyltransferase activity 1/1082 30/18639 0.0333333333333333 0.574214417744917 0.833962683162538 0.97748184259051 GO:0043996 histone H4K8 acetyltransferase activity 1/1082 30/18639 0.0333333333333333 0.574214417744917 0.833962683162538 0.97748184259051 GO:0043997 histone H4K12 acetyltransferase activity 1/1082 30/18639 0.0333333333333333 0.574214417744917 0.833962683162538 0.97748184259051 GO:0005184 neuropeptide hormone activity 1/1082 31/18639 0.032258064516129 0.55569137201121 0.843616741780311 0.98421953207703 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/1082 31/18639 0.032258064516129 0.55569137201121 0.843616741780311 0.98421953207703 GO:0005452 solute:inorganic anion antiporter activity 1/1082 31/18639 0.032258064516129 0.55569137201121 0.843616741780311 0.98421953207703 GO:0070325 lipoprotein particle receptor binding 1/1082 31/18639 0.032258064516129 0.55569137201121 0.843616741780311 0.98421953207703 GO:0042578 phosphoric ester hydrolase activity 17/1082 363/18639 0.046831955922865 0.806747529063106 0.850981879627893 0.989104308463617 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/1082 57/18639 0.0350877192982456 0.604436229205176 0.851129860602824 0.989104308463617 GO:0047498 calcium-dependent phospholipase A2 activity 1/1082 32/18639 0.03125 0.53832601663586 0.852709964340162 0.989104308463617 GO:0070717 poly-purine tract binding 1/1082 32/18639 0.03125 0.53832601663586 0.852709964340162 0.989104308463617 GO:0160041 neuropeptide activity 1/1082 32/18639 0.03125 0.53832601663586 0.852709964340162 0.989104308463617 GO:0005253 monoatomic anion channel activity 4/1082 103/18639 0.0388349514563107 0.668987671159126 0.855596773495483 0.991312123774077 GO:0008408 3'-5' exonuclease activity 2/1082 58/18639 0.0344827586206897 0.594014914908535 0.85787599327022 0.992811712073917 GO:0030165 PDZ domain binding 3/1082 83/18639 0.036144578313253 0.622642139723404 0.867542859347057 0.999431033573459 GO:0008175 tRNA methyltransferase activity 1/1082 34/18639 0.0294117647058824 0.506659780363162 0.869342223198151 0.999431033573459 GO:0016831 carboxy-lyase activity 1/1082 34/18639 0.0294117647058824 0.506659780363162 0.869342223198151 0.999431033573459 GO:0090482 vitamin transmembrane transporter activity 1/1082 34/18639 0.0294117647058824 0.506659780363162 0.869342223198151 0.999431033573459 GO:0008013 beta-catenin binding 4/1082 106/18639 0.0377358490566038 0.650054057824434 0.870368900724527 0.999431033573459 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/1082 60/18639 0.0333333333333333 0.574214417744917 0.870536158211802 0.999431033573459 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/1082 60/18639 0.0333333333333333 0.574214417744917 0.870536158211802 0.999431033573459 GO:0016836 hydro-lyase activity 2/1082 61/18639 0.0327868852459016 0.564801066634344 0.876469621905161 0.999999948432757 GO:0000175 3'-5'-RNA exonuclease activity 1/1082 35/18639 0.0285714285714286 0.4921837866385 0.876940810378995 0.999999948432757 GO:0010485 histone H4 acetyltransferase activity 1/1082 35/18639 0.0285714285714286 0.4921837866385 0.876940810378995 0.999999948432757 GO:0004620 phospholipase activity 4/1082 109/18639 0.036697247706422 0.632162661737523 0.883820795235755 0.999999948432757 GO:0000993 RNA polymerase II complex binding 1/1082 36/18639 0.0277777777777778 0.478512014787431 0.884097875696664 0.999999948432757 GO:0004190 aspartic-type endopeptidase activity 1/1082 36/18639 0.0277777777777778 0.478512014787431 0.884097875696664 0.999999948432757 GO:0030551 cyclic nucleotide binding 1/1082 37/18639 0.027027027027027 0.465579257631014 0.890839051770212 0.999999948432757 GO:0070001 aspartic-type peptidase activity 1/1082 37/18639 0.027027027027027 0.465579257631014 0.890839051770212 0.999999948432757 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/1082 38/18639 0.0263157894736842 0.453327171903882 0.897188484411037 0.999999948432757 GO:0042887 amide transmembrane transporter activity 1/1082 38/18639 0.0263157894736842 0.453327171903882 0.897188484411037 0.999999948432757 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/1082 91/18639 0.032967032967033 0.567904369198269 0.90458687176509 0.999999948432757 GO:0004175 endopeptidase activity 18/1082 405/18639 0.0444444444444444 0.765619223659889 0.905911381621385 0.999999948432757 GO:0008173 RNA methyltransferase activity 2/1082 67/18639 0.0298507462686567 0.514221866637239 0.907097211719477 0.999999948432757 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/1082 67/18639 0.0298507462686567 0.514221866637239 0.907097211719477 0.999999948432757 GO:0004532 RNA exonuclease activity 1/1082 40/18639 0.025 0.430660813308688 0.908801780610124 0.999999948432757 GO:0030331 nuclear estrogen receptor binding 1/1082 40/18639 0.025 0.430660813308688 0.908801780610124 0.999999948432757 GO:0071855 neuropeptide receptor binding 1/1082 40/18639 0.025 0.430660813308688 0.908801780610124 0.999999948432757 GO:0071949 FAD binding 1/1082 40/18639 0.025 0.430660813308688 0.908801780610124 0.999999948432757 GO:0140767 enzyme-substrate adaptor activity 5/1082 139/18639 0.0359712230215827 0.61965584648732 0.911660742924658 0.999999948432757 GO:0035402 histone H3T11 kinase activity 10/1082 247/18639 0.0404858299595142 0.697426418313664 0.913678820328456 0.999999948432757 GO:0001727 lipid kinase activity 1/1082 41/18639 0.024390243902439 0.420156891032866 0.914107252591405 0.999999948432757 GO:0004713 protein tyrosine kinase activity 5/1082 140/18639 0.0357142857142857 0.615229733298125 0.914713219577663 0.999999948432757 GO:0002039 p53 binding 2/1082 69/18639 0.0289855072463768 0.49931688499558 0.915617903279391 0.999999948432757 GO:0016279 protein-lysine N-methyltransferase activity 2/1082 69/18639 0.0289855072463768 0.49931688499558 0.915617903279391 0.999999948432757 GO:0004402 histone acetyltransferase activity 1/1082 42/18639 0.0238095238095238 0.410153155532083 0.919104346509897 0.999999948432757 GO:0016278 lysine N-methyltransferase activity 2/1082 70/18639 0.0285714285714286 0.4921837866385 0.919597685006196 0.999999948432757 GO:0016782 transferase activity, transferring sulphur-containing groups 2/1082 70/18639 0.0285714285714286 0.4921837866385 0.919597685006196 0.999999948432757 GO:0005096 GTPase activator activity 11/1082 271/18639 0.040590405904059 0.699227888766873 0.920831413571307 0.999999948432757 GO:0061630 ubiquitin protein ligase activity 15/1082 353/18639 0.0424929178470255 0.73200138239437 0.921150420073305 0.999999948432757 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/1082 43/18639 0.0232558139534884 0.400614710054593 0.923810971077101 0.999999948432757 GO:0005245 voltage-gated calcium channel activity 1/1082 43/18639 0.0232558139534884 0.400614710054593 0.923810971077101 0.999999948432757 GO:0048156 tau protein binding 1/1082 43/18639 0.0232558139534884 0.400614710054593 0.923810971077101 0.999999948432757 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 6/1082 167/18639 0.0359281437125748 0.618913743677156 0.927357175916022 0.999999948432757 GO:0016874 ligase activity 6/1082 167/18639 0.0359281437125748 0.618913743677156 0.927357175916022 0.999999948432757 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 4/1082 122/18639 0.0327868852459016 0.564801066634344 0.928980009696167 0.999999948432757 GO:0003678 DNA helicase activity 2/1082 74/18639 0.027027027027027 0.465579257631014 0.933815513797774 0.999999948432757 GO:0106310 protein serine kinase activity 15/1082 361/18639 0.0415512465373961 0.715779745111392 0.934860562279494 0.999999948432757 GO:0008236 serine-type peptidase activity 7/1082 194/18639 0.0360824742268041 0.621572307868209 0.938064935960644 0.999999948432757 GO:0008509 monoatomic anion transmembrane transporter activity 5/1082 149/18639 0.0335570469798658 0.578068205783473 0.938256390297278 0.999999948432757 GO:0005504 fatty acid binding 1/1082 47/18639 0.0212765957446809 0.366519841113777 0.940055821646014 0.999999948432757 GO:0061749 forked DNA-dependent helicase activity 1/1082 47/18639 0.0212765957446809 0.366519841113777 0.940055821646014 0.999999948432757 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/1082 47/18639 0.0212765957446809 0.366519841113777 0.940055821646014 0.999999948432757 GO:0009378 four-way junction helicase activity 1/1082 48/18639 0.0208333333333333 0.358884011090573 0.943544397430169 0.999999948432757 GO:0036121 double-stranded DNA helicase activity 1/1082 48/18639 0.0208333333333333 0.358884011090573 0.943544397430169 0.999999948432757 GO:0043138 3'-5' DNA helicase activity 1/1082 48/18639 0.0208333333333333 0.358884011090573 0.943544397430169 0.999999948432757 GO:0017171 serine hydrolase activity 7/1082 198/18639 0.0353535353535354 0.609015291547639 0.945656338803477 0.999999948432757 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 9/1082 243/18639 0.037037037037037 0.638016019716574 0.947370784117676 0.999999948432757 GO:0004676 3-phosphoinositide-dependent protein kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0004711 ribosomal protein S6 kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0035175 histone H3S10 kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0035979 histone H2AXS139 kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0044022 histone H3S28 kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0044023 histone H4S1 kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0044024 histone H2AS1 kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0044025 histone H2BS14 kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0072354 histone H3T3 kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0072371 histone H2AS121 kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0072518 Rho-dependent protein serine/threonine kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0140823 histone H2BS36 kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0140855 histone H3S57 kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0140995 histone H2A kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0140997 histone H4 kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0140998 histone H2B kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:1990244 histone H2AT120 kinase activity 9/1082 245/18639 0.036734693877551 0.632807725678072 0.950467507317958 0.999999948432757 GO:0004677 DNA-dependent protein kinase activity 9/1082 246/18639 0.0365853658536585 0.630235336549299 0.951954593213309 0.999999948432757 GO:0140857 histone H3T45 kinase activity 9/1082 246/18639 0.0365853658536585 0.630235336549299 0.951954593213309 0.999999948432757 GO:0035403 histone H3T6 kinase activity 9/1082 247/18639 0.0364372469635627 0.627683776482298 0.953401996389627 0.999999948432757 GO:0004679 AMP-activated protein kinase activity 9/1082 248/18639 0.0362903225806452 0.625152793512611 0.954810579340881 0.999999948432757 GO:0005254 chloride channel activity 2/1082 83/18639 0.0240963855421687 0.415094759815603 0.957586574416508 0.999999948432757 GO:0004222 metalloendopeptidase activity 3/1082 110/18639 0.0272727272727273 0.46981179633675 0.957956137138351 0.999999948432757 GO:0008146 sulfotransferase activity 1/1082 53/18639 0.0188679245283019 0.325027028912217 0.9581702212023 0.999999948432757 GO:0038064 collagen receptor activity 1/1082 53/18639 0.0188679245283019 0.325027028912217 0.9581702212023 0.999999948432757 GO:0004527 exonuclease activity 2/1082 84/18639 0.0238095238095238 0.410153155532083 0.959654939608431 0.999999948432757 GO:0030170 pyridoxal phosphate binding 1/1082 56/18639 0.0178571428571429 0.307614866649063 0.965058998415943 0.999999948432757 GO:0170055 lipid transmembrane transporter activity 1/1082 56/18639 0.0178571428571429 0.307614866649063 0.965058998415943 0.999999948432757 GO:0070279 vitamin B6 binding 1/1082 57/18639 0.0175438596491228 0.302218114602588 0.967093447305463 0.999999948432757 GO:0017116 single-stranded DNA helicase activity 1/1082 58/18639 0.0172413793103448 0.297007457454267 0.969009542990292 0.999999948432757 GO:0003730 mRNA 3'-UTR binding 9/1082 262/18639 0.0343511450381679 0.591747682408884 0.970910605383847 0.999999948432757 GO:0015026 coreceptor activity 1/1082 61/18639 0.0163934426229508 0.282400533317172 0.974114528012007 0.999999948432757 GO:0141003 histone H2AX kinase activity 13/1082 354/18639 0.0367231638418079 0.632609104295247 0.974187075420454 0.999999948432757 GO:0051213 dioxygenase activity 2/1082 93/18639 0.021505376344086 0.37046091467414 0.974387004730098 0.999999948432757 GO:0015108 chloride transmembrane transporter activity 3/1082 121/18639 0.0247933884297521 0.427101633033409 0.974390562043588 0.999999948432757 GO:0008528 G protein-coupled peptide receptor activity 3/1082 122/18639 0.0245901639344262 0.423600799975758 0.975535365884279 0.999999948432757 GO:0015179 L-amino acid transmembrane transporter activity 1/1082 62/18639 0.0161290322580645 0.277845686005605 0.975622121977505 0.999999948432757 GO:0140996 histone H3 kinase activity 13/1082 357/18639 0.0364145658263305 0.62729306140201 0.976319756148495 0.999999948432757 GO:1901682 sulfur compound transmembrane transporter activity 1/1082 63/18639 0.0158730158730159 0.273435437021389 0.977041988695508 0.999999948432757 GO:0035173 histone kinase activity 13/1082 360/18639 0.0361111111111111 0.62206561922366 0.97829206336648 0.999999948432757 GO:0005249 voltage-gated potassium channel activity 2/1082 98/18639 0.0204081632653061 0.351559847598929 0.980163107659052 0.999999948432757 GO:0008168 methyltransferase activity 6/1082 204/18639 0.0294117647058824 0.506659780363162 0.980757128831873 0.999999948432757 GO:0001653 peptide receptor activity 3/1082 128/18639 0.0234375 0.403744512476895 0.981445848335503 0.999999948432757 GO:0016500 protein-hormone receptor activity 1/1082 67/18639 0.0149253731343284 0.25711093331862 0.981941849532537 0.999999948432757 GO:0003777 microtubule motor activity 1/1082 68/18639 0.0147058823529412 0.253329890181581 0.982993912789365 0.999999948432757 GO:0046943 carboxylic acid transmembrane transporter activity 5/1082 188/18639 0.0265957446808511 0.458149801392221 0.986436740636803 0.999999948432757 GO:0015297 antiporter activity 3/1082 135/18639 0.0222222222222222 0.382809611829945 0.986620776475167 0.999999948432757 GO:0005518 collagen binding 1/1082 72/18639 0.0138888888888889 0.239256007393715 0.986624363093803 0.999999948432757 GO:0004497 monooxygenase activity 2/1082 106/18639 0.0188679245283019 0.325027028912217 0.986874487790058 0.999999948432757 GO:0005342 organic acid transmembrane transporter activity 5/1082 189/18639 0.0264550264550265 0.455725728368982 0.986981257600235 0.999999948432757 GO:0016741 transferase activity, transferring one-carbon groups 6/1082 215/18639 0.027906976744186 0.480737652065512 0.98739580225066 0.999999948432757 GO:0015103 inorganic anion transmembrane transporter activity 4/1082 165/18639 0.0242424242424242 0.417610485632667 0.988106964836065 0.999999948432757 GO:0140101 catalytic activity, acting on a tRNA 3/1082 139/18639 0.0215827338129496 0.371793507892392 0.988922830455062 0.999999948432757 GO:0005201 extracellular matrix structural constituent 4/1082 168/18639 0.0238095238095238 0.410153155532083 0.989576884356012 0.999999948432757 GO:0008514 organic anion transmembrane transporter activity 8/1082 269/18639 0.0297397769516729 0.512310261185056 0.989643981568756 0.999999948432757 GO:0022843 voltage-gated monoatomic cation channel activity 3/1082 143/18639 0.020979020979021 0.361393689489808 0.990841109923872 0.999999948432757 GO:0033293 monocarboxylic acid binding 1/1082 79/18639 0.0126582278481013 0.218056108004399 0.991214805889455 0.999999948432757 GO:0005244 voltage-gated monoatomic ion channel activity 4/1082 173/18639 0.023121387283237 0.39829901808896 0.991648835363788 0.999999948432757 GO:0015101 organic cation transmembrane transporter activity 1/1082 81/18639 0.0123456790123457 0.212672006572191 0.992209282810028 0.999999948432757 GO:0022832 voltage-gated channel activity 4/1082 175/18639 0.0228571428571429 0.3937470293108 0.992361820638886 0.999999948432757 GO:0019842 vitamin binding 3/1082 150/18639 0.02 0.34452865064695 0.993453750257912 0.999999948432757 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/1082 181/18639 0.0220994475138122 0.38069464159884 0.994167255230267 0.999999948432757 GO:0050660 flavin adenine dinucleotide binding 1/1082 86/18639 0.0116279069767442 0.200307355027297 0.994230777664726 0.999999948432757 GO:0005267 potassium channel activity 2/1082 124/18639 0.0161290322580645 0.277845686005605 0.994897980292194 0.999999948432757 GO:0016757 glycosyltransferase activity 7/1082 267/18639 0.0262172284644195 0.451629317327463 0.995605908543957 0.999999948432757 GO:0005262 calcium channel activity 2/1082 131/18639 0.0152671755725191 0.262998969959504 0.996484570315767 0.999999948432757 GO:0030594 neurotransmitter receptor activity 1/1082 97/18639 0.0103092783505155 0.177592087962345 0.997021639099357 0.999999948432757 GO:0015171 amino acid transmembrane transporter activity 1/1082 102/18639 0.00980392156862745 0.168886593454387 0.997795037956605 0.999999948432757 GO:0004252 serine-type endopeptidase activity 3/1082 176/18639 0.0170454545454545 0.293632372710469 0.998174643940466 0.999999948432757 GO:0015293 symporter activity 2/1082 146/18639 0.0136986301369863 0.235978527840377 0.998429983962055 0.999999948432757 GO:0015085 calcium ion transmembrane transporter activity 2/1082 147/18639 0.0136054421768707 0.234373231732619 0.998512647227804 0.999999948432757 GO:0031406 carboxylic acid binding 3/1082 187/18639 0.0160427807486631 0.276359880198088 0.998949442008191 0.999999948432757 GO:0015294 solute:monoatomic cation symporter activity 1/1082 116/18639 0.00862068965517241 0.148503728727134 0.999050282285697 0.999999948432757 GO:0043177 organic acid binding 3/1082 189/18639 0.0158730158730159 0.273435437021389 0.999050487828486 0.999999948432757 GO:0015079 potassium ion transmembrane transporter activity 2/1082 160/18639 0.0125 0.215330406654344 0.999266339002926 0.999999948432757 GO:0015291 secondary active transmembrane transporter activity 5/1082 287/18639 0.0174216027874564 0.300112065023476 0.999835276067915 0.999999948432757 GO:0005216 monoatomic ion channel activity 10/1082 448/18639 0.0223214285714286 0.384518583311328 0.999930878143081 0.999999948432757 GO:0005261 monoatomic cation channel activity 6/1082 341/18639 0.0175953079178886 0.303104384733387 0.999946521737277 0.999999948432757 GO:0045182 translation regulator activity 6/1082 356/18639 0.0168539325842697 0.290333132567655 0.999973589155738 0.999999948432757 GO:0016758 hexosyltransferase activity 1/1082 197/18639 0.0050761421319797 0.0874438199611548 0.999992829785409 0.999999948432757 GO:0022836 gated channel activity 4/1082 318/18639 0.0125786163522013 0.216684685941478 0.999992893226369 0.999999948432757 GO:0046873 metal ion transmembrane transporter activity 7/1082 450/18639 0.0155555555555556 0.267966728280961 0.999998706018227 0.999999948432757 GO:0030371 translation repressor activity 2/1082 329/18639 0.0060790273556231 0.104719954603936 0.999999948432757 0.999999948432757