ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	71/480	175/18639	0.405714285714286	15.7543928571429	9.39373888079442e-67	6.2280488779667e-64
GO:0045296	cadherin binding	43/480	334/18639	0.12874251497006	4.99923278443114	2.53186403412984e-18	8.3931292731404e-16
GO:0019843	rRNA binding	18/480	65/18639	0.276923076923077	10.7532692307692	2.9524299585921e-14	6.52487020848855e-12
GO:0044389	ubiquitin-like protein ligase binding	32/480	322/18639	0.0993788819875776	3.85900621118012	7.09859472734902e-11	1.1765920760581e-08
GO:0031625	ubiquitin protein ligase binding	30/480	302/18639	0.0993377483443709	3.85740894039735	2.85925678880854e-10	3.79137450196012e-08
GO:0008135	translation factor activity, RNA binding	15/480	83/18639	0.180722891566265	7.01769578313253	2.85489617509677e-09	3.15466027348193e-07
GO:0180051	translation factor activity	15/480	84/18639	0.178571428571429	6.93415178571429	3.3944651530789e-09	3.21504342355902e-07
GO:0051082	unfolded protein binding	17/480	121/18639	0.140495867768595	5.45563016528926	1.36577254797147e-08	1.13188399913135e-06
GO:0016209	antioxidant activity	14/480	86/18639	0.162790697674419	6.32136627906977	3.89222071051753e-08	2.86726925674791e-06
GO:0140662	ATP-dependent protein folding chaperone	10/480	40/18639	0.25	9.7078125	4.95269067782836e-08	3.2836339194002e-06
GO:0003743	translation initiation factor activity	11/480	51/18639	0.215686274509804	8.37536764705882	5.53811326007036e-08	3.33797190129695e-06
GO:0003697	single-stranded DNA binding	16/480	121/18639	0.132231404958678	5.13471074380165	8.70891554252776e-08	4.81167583724659e-06
GO:0043021	ribonucleoprotein complex binding	19/480	177/18639	0.107344632768362	4.16832627118644	1.6339034579656e-07	8.33290763562456e-06
GO:0004601	peroxidase activity	11/480	57/18639	0.192982456140351	7.49375	1.86649362582684e-07	8.83918052802283e-06
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	11/480	59/18639	0.186440677966102	7.23972457627119	2.70277136799897e-07	1.19462494465554e-05
GO:0009055	electron transfer activity	15/480	116/18639	0.129310344827586	5.02128232758621	2.96728852885579e-07	1.22957018414462e-05
GO:0055105	ubiquitin-protein transferase inhibitor activity	6/480	15/18639	0.4	15.5325	1.16149986154738e-06	4.42600825245076e-05
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	11/480	68/18639	0.161764705882353	6.28152573529412	1.20163119976039e-06	4.42600825245076e-05
GO:0048027	mRNA 5'-UTR binding	7/480	24/18639	0.291666666666667	11.32578125	1.70184988573026e-06	5.93856039073242e-05
GO:0055106	ubiquitin-protein transferase regulator activity	8/480	36/18639	0.222222222222222	8.62916666666667	2.92808452631047e-06	9.70660020471922e-05
GO:0098641	cadherin binding involved in cell-cell adhesion	6/480	18/18639	0.333333333333333	12.94375	4.0335496868599e-06	0.000127344925828005
GO:1990948	ubiquitin ligase inhibitor activity	5/480	11/18639	0.454545454545455	17.6505681818182	4.50841824362939e-06	0.000135867331614831
GO:0048306	calcium-dependent protein binding	11/480	80/18639	0.1375	5.339296875	6.22045617592085e-06	0.000179311410636327
GO:0004859	phospholipase inhibitor activity	5/480	12/18639	0.416666666666667	16.1796875	7.56511218350933e-06	0.000208986224069445
GO:0061650	ubiquitin-like protein conjugating enzyme activity	8/480	41/18639	0.195121951219512	7.57682926829268	8.25769895555267e-06	0.000218994176301257
GO:0003684	damaged DNA binding	10/480	74/18639	0.135135135135135	5.24746621621622	1.91873693429473e-05	0.000489277918245157
GO:0044183	protein folding chaperone	10/480	75/18639	0.133333333333333	5.1775	2.16370126091989e-05	0.000531308865181439
GO:0043022	ribosome binding	12/480	112/18639	0.107142857142857	4.16049107142857	3.18188853589455e-05	0.000753425749749317
GO:0055102	lipase inhibitor activity	5/480	16/18639	0.3125	12.134765625	3.83054619039948e-05	0.000875742111805122
GO:0042162	telomeric DNA binding	7/480	38/18639	0.184210526315789	7.153125	4.54229711450087e-05	0.00100384766230469
GO:0004857	enzyme inhibitor activity	25/480	416/18639	0.0600961538461538	2.33360877403846	8.42786717319205e-05	0.00180247610833107
GO:0015078	proton transmembrane transporter activity	15/480	185/18639	0.0810810810810811	3.14847972972973	9.26674773173213e-05	0.00191995429566825
GO:0043024	ribosomal small subunit binding	5/480	20/18639	0.25	9.7078125	0.000124853478684066	0.00250841988992533
GO:0005200	structural constituent of cytoskeleton	11/480	112/18639	0.0982142857142857	3.81378348214286	0.000148924709776074	0.00290403184063344
GO:0070182	DNA polymerase binding	5/480	21/18639	0.238095238095238	9.24553571428571	0.000160420208958334	0.00303881710112502
GO:0061133	endopeptidase activator activity	5/480	22/18639	0.227272727272727	8.82528409090909	0.00020323466092666	0.00354591000511514
GO:0070034	telomerase RNA binding	5/480	22/18639	0.227272727272727	8.82528409090909	0.00020323466092666	0.00354591000511514
GO:0140517	protein-RNA adaptor activity	5/480	22/18639	0.227272727272727	8.82528409090909	0.00020323466092666	0.00354591000511514
GO:0022853	active monoatomic ion transmembrane transporter activity	11/480	118/18639	0.0932203389830508	3.61986228813559	0.000236550141146501	0.00402135239949051
GO:0061631	ubiquitin conjugating enzyme activity	6/480	35/18639	0.171428571428571	6.65678571428571	0.000243251694821622	0.00403189684166838
GO:0004602	glutathione peroxidase activity	5/480	23/18639	0.217391304347826	8.44157608695652	0.000254228302721811	0.00407488557583199
GO:0019855	calcium channel inhibitor activity	4/480	13/18639	0.307692307692308	11.9480769230769	0.000258137547790262	0.00407488557583199
GO:1990825	sequence-specific mRNA binding	4/480	14/18639	0.285714285714286	11.0946428571429	0.000354063529465042	0.00545916558221681
GO:0003925	G protein activity	7/480	54/18639	0.12962962962963	5.03368055555555	0.000447114090741305	0.00667275565182258
GO:0004129	cytochrome-c oxidase activity	4/480	15/18639	0.266666666666667	10.355	0.000473030943643532	0.00667275565182258
GO:0031386	protein tag activity	4/480	15/18639	0.266666666666667	10.355	0.000473030943643532	0.00667275565182258
GO:0141047	molecular tag activity	4/480	15/18639	0.266666666666667	10.355	0.000473030943643532	0.00667275565182258
GO:0008137	NADH dehydrogenase (ubiquinone) activity	6/480	41/18639	0.146341463414634	5.68262195121951	0.000591472824020372	0.00816971838178139
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/480	16/18639	0.25	9.7078125	0.00061793943755671	0.00836109892041017
GO:0003954	NADH dehydrogenase activity	6/480	44/18639	0.136363636363636	5.29517045454545	0.000870100655156452	0.0115375346873746
GO:0070628	proteasome binding	4/480	18/18639	0.222222222222222	8.62916666666667	0.000997366734976493	0.0129657675546944
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/480	21/18639	0.19047619047619	7.39642857142857	0.00183504093741691	0.0233967719520657
GO:0042393	histone binding	15/480	247/18639	0.0607287449392713	2.35817307692308	0.00193554657906148	0.0242125921116559
GO:0003727	single-stranded RNA binding	8/480	89/18639	0.0898876404494382	3.49044943820225	0.0020810248510578	0.0255503606713207
GO:0061134	peptidase regulator activity	14/480	226/18639	0.0619469026548673	2.40547566371681	0.00225284530269794	0.0260875230588081
GO:0072341	modified amino acid binding	8/480	91/18639	0.0879120879120879	3.41373626373626	0.00239529688930853	0.0260875230588081
GO:0004523	RNA-DNA hybrid ribonuclease activity	3/480	11/18639	0.272727272727273	10.5903409090909	0.00240020951219803	0.0260875230588081
GO:0010854	adenylate cyclase regulator activity	3/480	11/18639	0.272727272727273	10.5903409090909	0.00240020951219803	0.0260875230588081
GO:0034511	U3 snoRNA binding	3/480	11/18639	0.272727272727273	10.5903409090909	0.00240020951219803	0.0260875230588081
GO:0050786	RAGE receptor binding	3/480	11/18639	0.272727272727273	10.5903409090909	0.00240020951219803	0.0260875230588081
GO:0070990	snRNP binding	3/480	11/18639	0.272727272727273	10.5903409090909	0.00240020951219803	0.0260875230588081
GO:0017069	snRNA binding	6/480	54/18639	0.111111111111111	4.31458333333333	0.00256482026050727	0.0274270295599406
GO:0044325	transmembrane transporter binding	10/480	136/18639	0.0735294117647059	2.85523897058824	0.00276283538986427	0.0290755533885716
GO:0098632	cell-cell adhesion mediator activity	6/480	55/18639	0.109090909090909	4.23613636363636	0.0028175176395037	0.0291877217967336
GO:0061135	endopeptidase regulator activity	12/480	184/18639	0.0652173913043478	2.53247282608696	0.0029860345582889	0.0304575524945467
GO:0051015	actin filament binding	13/480	209/18639	0.062200956937799	2.41534090909091	0.00307760816247946	0.0306098809443269
GO:0000217	DNA secondary structure binding	5/480	39/18639	0.128205128205128	4.97836538461538	0.00310200441259063	0.0306098809443269
GO:0010853	cyclase activator activity	3/480	12/18639	0.25	9.7078125	0.00313947496864892	0.0306098809443269
GO:0016504	peptidase activator activity	6/480	57/18639	0.105263157894737	4.0875	0.00337824221923107	0.0322222730548797
GO:0098631	cell adhesion mediator activity	7/480	76/18639	0.0921052631578947	3.5765625	0.00340204994546242	0.0322222730548797
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	6/480	58/18639	0.103448275862069	4.01702586206897	0.00368785487948155	0.0344372927478347
GO:0015399	primary active transmembrane transporter activity	11/480	166/18639	0.0662650602409639	2.57315512048193	0.0038863645133033	0.0357869398933346
GO:0140666	annealing activity	3/480	13/18639	0.230769230769231	8.96105769230769	0.00400387619490651	0.0359994035121771
GO:0001786	phosphatidylserine binding	6/480	59/18639	0.101694915254237	3.9489406779661	0.00401803297119322	0.0359994035121771
GO:0016835	carbon-oxygen lyase activity	7/480	79/18639	0.0886075949367089	3.44074367088608	0.00422437426509571	0.0373434685034461
GO:0031492	nucleosomal DNA binding	5/480	42/18639	0.119047619047619	4.62276785714286	0.00430334607149451	0.0375410321763271
GO:0008200	ion channel inhibitor activity	5/480	43/18639	0.116279069767442	4.51526162790698	0.00476853473292252	0.041058941921138
GO:0032036	myosin heavy chain binding	3/480	14/18639	0.214285714285714	8.32098214285714	0.00499927964911782	0.0419559798400647
GO:0044548	S100 protein binding	3/480	14/18639	0.214285714285714	8.32098214285714	0.00499927964911782	0.0419559798400647
GO:0016248	channel inhibitor activity	5/480	44/18639	0.113636363636364	4.41264204545454	0.00526833397366176	0.0436613178067218
GO:0141110	transporter inhibitor activity	5/480	45/18639	0.111111111111111	4.31458333333333	0.00580406930393411	0.0469328776573687
GO:0016829	lyase activity	12/480	200/18639	0.06	2.329875	0.00580466963484801	0.0469328776573687
GO:0000287	magnesium ion binding	13/480	230/18639	0.0565217391304348	2.1948097826087	0.00683522108192543	0.0541620425945323
GO:0031072	heat shock protein binding	9/480	131/18639	0.0687022900763359	2.66779580152672	0.00686215924274617	0.0541620425945323
GO:0008142	oxysterol binding	3/480	16/18639	0.1875	7.280859375	0.00740305006885478	0.0564163470764451
GO:0017070	U6 snRNA binding	3/480	16/18639	0.1875	7.280859375	0.00740305006885478	0.0564163470764451
GO:0043023	ribosomal large subunit binding	3/480	16/18639	0.1875	7.280859375	0.00740305006885478	0.0564163470764451
GO:0051087	protein-folding chaperone binding	9/480	134/18639	0.0671641791044776	2.60806902985075	0.00791948685317866	0.0596661339051983
GO:1990226	histone methyltransferase binding	3/480	17/18639	0.176470588235294	6.85257352941177	0.00881976155674841	0.0642903550557015
GO:0030515	snoRNA binding	4/480	32/18639	0.125	4.85390625	0.00882416638019433	0.0642903550557015
GO:0031369	translation initiation factor binding	4/480	32/18639	0.125	4.85390625	0.00882416638019433	0.0642903550557015
GO:0030544	Hsp70 protein binding	5/480	51/18639	0.0980392156862745	3.80698529411765	0.00984509151469624	0.070948866024387
GO:0000400	four-way junction DNA binding	3/480	18/18639	0.166666666666667	6.471875	0.0103842405211028	0.0724710680578016
GO:0000900	mRNA regulatory element binding translation repressor activity	3/480	18/18639	0.166666666666667	6.471875	0.0103842405211028	0.0724710680578016
GO:0003746	translation elongation factor activity	3/480	18/18639	0.166666666666667	6.471875	0.0103842405211028	0.0724710680578016
GO:0005246	calcium channel regulator activity	5/480	53/18639	0.0943396226415094	3.66332547169811	0.0115364638723508	0.0788523252306042
GO:0005544	calcium-dependent phospholipid binding	5/480	53/18639	0.0943396226415094	3.66332547169811	0.0115364638723508	0.0788523252306042
GO:0031491	nucleosome binding	6/480	74/18639	0.0810810810810811	3.14847972972973	0.0119837635639958	0.0810279340975607
GO:0008301	DNA binding, bending	3/480	19/18639	0.157894736842105	6.13125	0.0120991937792738	0.0810279340975607
GO:0003725	double-stranded RNA binding	6/480	75/18639	0.08	3.1065	0.0127513014522043	0.0845411286281147
GO:0017022	myosin binding	6/480	76/18639	0.0789473684210526	3.065625	0.0135526658670679	0.088932535276951
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	8/480	122/18639	0.0655737704918033	2.54631147540984	0.0136819285041463	0.088932535276951
GO:0010851	cyclase regulator activity	3/480	20/18639	0.15	5.8246875	0.0139668046413984	0.0899028298761857
GO:0003713	transcription coactivator activity	13/480	256/18639	0.05078125	1.9718994140625	0.0157350319940684	0.100310828962186
GO:0072542	protein phosphatase activator activity	3/480	21/18639	0.142857142857143	5.54732142857143	0.0159887652587286	0.100957632062258
GO:0019207	kinase regulator activity	14/480	287/18639	0.0487804878048781	1.89420731707317	0.0171604074223831	0.107333491707924
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	4/480	40/18639	0.1	3.883125	0.0191006382837568	0.117463721294665
GO:0005525	GTP binding	17/480	378/18639	0.044973544973545	1.74637896825397	0.0191343618398549	0.117463721294665
GO:0008171	O-methyltransferase activity	3/480	23/18639	0.130434782608696	5.06494565217391	0.0205002322422108	0.124694073179686
GO:0001530	lipopolysaccharide binding	4/480	41/18639	0.0975609756097561	3.78841463414634	0.0207470392682689	0.125048063953293
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	8/480	132/18639	0.0606060606060606	2.35340909090909	0.0210170801113338	0.125534451475804
GO:0008307	structural constituent of muscle	4/480	42/18639	0.0952380952380952	3.69821428571429	0.0224779543416136	0.133061461861516
GO:0016887	ATP hydrolysis activity	18/480	417/18639	0.0431654676258993	1.6761690647482	0.0233974869577286	0.137279060645788
GO:0003924	GTPase activity	15/480	331/18639	0.0453172205438066	1.75972432024169	0.0251516447220191	0.142365132341107
GO:0019211	phosphatase activator activity	3/480	25/18639	0.12	4.65975	0.0256384456621115	0.142365132341107
GO:0030957	Tat protein binding	2/480	10/18639	0.2	7.76625	0.0259717827919438	0.142365132341107
GO:0031720	haptoglobin binding	2/480	10/18639	0.2	7.76625	0.0259717827919438	0.142365132341107
GO:0031996	thioesterase binding	2/480	10/18639	0.2	7.76625	0.0259717827919438	0.142365132341107
GO:0047429	nucleoside triphosphate diphosphatase activity	2/480	10/18639	0.2	7.76625	0.0259717827919438	0.142365132341107
GO:0098505	G-rich strand telomeric DNA binding	2/480	10/18639	0.2	7.76625	0.0259717827919438	0.142365132341107
GO:0016651	oxidoreductase activity, acting on NAD(P)H	6/480	88/18639	0.0681818181818182	2.64758522727273	0.0260483251059734	0.142365132341107
GO:0019205	nucleobase-containing compound kinase activity	4/480	44/18639	0.0909090909090909	3.53011363636364	0.0261969021804149	0.142365132341107
GO:0019001	guanyl nucleotide binding	17/480	400/18639	0.0425	1.650328125	0.0307560699858934	0.161392846138295
GO:0032561	guanyl ribonucleotide binding	17/480	400/18639	0.0425	1.650328125	0.0307560699858934	0.161392846138295
GO:0005536	D-glucose binding	2/480	11/18639	0.181818181818182	7.06022727272727	0.0312099101874429	0.161392846138295
GO:0008199	ferric iron binding	2/480	11/18639	0.181818181818182	7.06022727272727	0.0312099101874429	0.161392846138295
GO:0015217	ADP transmembrane transporter activity	2/480	11/18639	0.181818181818182	7.06022727272727	0.0312099101874429	0.161392846138295
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/480	11/18639	0.181818181818182	7.06022727272727	0.0312099101874429	0.161392846138295
GO:0023026	MHC class II protein complex binding	3/480	27/18639	0.111111111111111	4.31458333333333	0.0314022279816592	0.161392846138295
GO:0003712	transcription coregulator activity	20/480	495/18639	0.0404040404040404	1.56893939393939	0.0323169949736889	0.164816674365813
GO:0019887	protein kinase regulator activity	12/480	255/18639	0.0470588235294118	1.82735294117647	0.0331435116653763	0.167741589573622
GO:0097110	scaffold protein binding	5/480	70/18639	0.0714285714285714	2.77366071428571	0.0342380351432193	0.171599083410974
GO:0097718	disordered domain specific binding	3/480	28/18639	0.107142857142857	4.16049107142857	0.0345168884157633	0.171599083410974
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	4/480	48/18639	0.0833333333333333	3.2359375	0.0346821676878891	0.171599083410974
GO:0032182	ubiquitin-like protein binding	7/480	120/18639	0.0583333333333333	2.26515625	0.0356906770160999	0.175280880456846
GO:0043047	single-stranded telomeric DNA binding	2/480	12/18639	0.166666666666667	6.471875	0.0368239972312017	0.176915291045556
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	2/480	12/18639	0.166666666666667	6.471875	0.0368239972312017	0.176915291045556
GO:1990247	N6-methyladenosine-containing RNA reader activity	2/480	12/18639	0.166666666666667	6.471875	0.0368239972312017	0.176915291045556
GO:0003779	actin binding	18/480	443/18639	0.0406320541760722	1.5777934537246	0.0389787786992358	0.185920361709305
GO:0003730	mRNA 3'-UTR binding	12/480	262/18639	0.0458015267175573	1.77853053435115	0.0394700432629128	0.186918847737937
GO:0015631	tubulin binding	16/480	385/18639	0.0415584415584416	1.61376623376623	0.041942509838028	0.194319360087971
GO:0003678	DNA helicase activity	5/480	74/18639	0.0675675675675676	2.62373310810811	0.0419823759736622	0.194319360087971
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/480	13/18639	0.153846153846154	5.97403846153846	0.0427912919650735	0.194319360087971
GO:0005542	folic acid binding	2/480	13/18639	0.153846153846154	5.97403846153846	0.0427912919650735	0.194319360087971
GO:0019104	DNA N-glycosylase activity	2/480	13/18639	0.153846153846154	5.97403846153846	0.0427912919650735	0.194319360087971
GO:0031432	titin binding	2/480	13/18639	0.153846153846154	5.97403846153846	0.0427912919650735	0.194319360087971
GO:0043130	ubiquitin binding	6/480	100/18639	0.06	2.329875	0.0445120674562599	0.200758508323132
GO:0031490	chromatin DNA binding	7/480	128/18639	0.0546875	2.123583984375	0.0478009866538113	0.211214227715922
GO:0051540	metal cluster binding	5/480	77/18639	0.0649350649350649	2.52150974025974	0.0484299174307704	0.211214227715922
GO:0140142	nucleocytoplasmic carrier activity	3/480	32/18639	0.09375	3.6404296875	0.0484955357595663	0.211214227715922
GO:0005344	oxygen carrier activity	2/480	14/18639	0.142857142857143	5.54732142857143	0.0490899606843995	0.211214227715922
GO:0005347	ATP transmembrane transporter activity	2/480	14/18639	0.142857142857143	5.54732142857143	0.0490899606843995	0.211214227715922
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	2/480	14/18639	0.142857142857143	5.54732142857143	0.0490899606843995	0.211214227715922
GO:0098847	sequence-specific single stranded DNA binding	2/480	14/18639	0.142857142857143	5.54732142857143	0.0490899606843995	0.211214227715922
GO:0140297	DNA-binding transcription factor binding	19/480	488/18639	0.0389344262295082	1.51187243852459	0.0493788918491221	0.211214227715922
GO:0008017	microtubule binding	12/480	276/18639	0.0434782608695652	1.6883152173913	0.0545726263211874	0.231933661865046
GO:0000049	tRNA binding	5/480	80/18639	0.0625	2.426953125	0.0554303124783427	0.232133605129268
GO:0046982	protein heterodimerization activity	15/480	369/18639	0.040650406504065	1.57850609756098	0.0558085640717845	0.232133605129268
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	3/480	34/18639	0.0882352941176471	3.42628676470588	0.0563703023013758	0.232133605129268
GO:0030332	cyclin binding	3/480	34/18639	0.0882352941176471	3.42628676470588	0.0563703023013758	0.232133605129268
GO:0051427	hormone receptor binding	3/480	34/18639	0.0882352941176471	3.42628676470588	0.0563703023013758	0.232133605129268
GO:0019888	protein phosphatase regulator activity	6/480	107/18639	0.0560747663551402	2.17745327102804	0.0582968329707108	0.238585186787539
GO:0005159	insulin-like growth factor receptor binding	2/480	16/18639	0.125	4.85390625	0.0625984852969785	0.251532095466041
GO:0005521	lamin binding	2/480	16/18639	0.125	4.85390625	0.0625984852969785	0.251532095466041
GO:0097027	ubiquitin-protein transferase activator activity	2/480	16/18639	0.125	4.85390625	0.0625984852969785	0.251532095466041
GO:0045505	dynein intermediate chain binding	3/480	36/18639	0.0833333333333333	3.2359375	0.064810378381233	0.25885108955878
GO:0023023	MHC protein complex binding	3/480	37/18639	0.0810810810810811	3.14847972972973	0.0692356217012849	0.272099029003136
GO:0004550	nucleoside diphosphate kinase activity	2/480	17/18639	0.117647058823529	4.56838235294118	0.0697689817956759	0.272099029003136
GO:0031489	myosin V binding	2/480	17/18639	0.117647058823529	4.56838235294118	0.0697689817956759	0.272099029003136
GO:0045236	CXCR chemokine receptor binding	2/480	17/18639	0.117647058823529	4.56838235294118	0.0697689817956759	0.272099029003136
GO:0030414	peptidase inhibitor activity	8/480	169/18639	0.0473372781065089	1.83816568047337	0.0713965784868208	0.276818313080481
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	4/480	61/18639	0.0655737704918033	2.54631147540984	0.0720208029116383	0.277615071688466
GO:0008308	voltage-gated monoatomic anion channel activity	2/480	18/18639	0.111111111111111	4.31458333333333	0.0771920744549975	0.292447687792362
GO:0031690	adrenergic receptor binding	2/480	18/18639	0.111111111111111	4.31458333333333	0.0771920744549975	0.292447687792362
GO:1990381	ubiquitin-specific protease binding	2/480	18/18639	0.111111111111111	4.31458333333333	0.0771920744549975	0.292447687792362
GO:0016776	phosphotransferase activity, phosphate group as acceptor	3/480	39/18639	0.0769230769230769	2.98701923076923	0.0784817829747831	0.29564444381978
GO:0019208	phosphatase regulator activity	6/480	117/18639	0.0512820512820513	1.99134615384615	0.0819580839731244	0.305113590405384
GO:0004536	DNA nuclease activity	4/480	64/18639	0.0625	2.426953125	0.0827044178744398	0.305113590405384
GO:0015036	disulfide oxidoreductase activity	3/480	40/18639	0.075	2.91234375	0.0832964703821637	0.305113590405384
GO:0061791	GTPase motor activity	3/480	40/18639	0.075	2.91234375	0.0832964703821637	0.305113590405384
GO:1990606	membrane scission GTPase motor activity	3/480	40/18639	0.075	2.91234375	0.0832964703821637	0.305113590405384
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/480	19/18639	0.105263157894737	4.0875	0.0848500604168474	0.307407595936447
GO:0097001	ceramide binding	2/480	19/18639	0.105263157894737	4.0875	0.0848500604168474	0.307407595936447
GO:0042288	MHC class I protein binding	2/480	20/18639	0.1	3.883125	0.0927259777252306	0.329005940697198
GO:0061608	nuclear import signal receptor activity	2/480	20/18639	0.1	3.883125	0.0927259777252306	0.329005940697198
GO:0004520	DNA endonuclease activity	3/480	42/18639	0.0714285714285714	2.77366071428571	0.0932927855973954	0.329005940697198
GO:0035198	miRNA binding	3/480	42/18639	0.0714285714285714	2.77366071428571	0.0932927855973954	0.329005940697198
GO:0042056	chemoattractant activity	3/480	42/18639	0.0714285714285714	2.77366071428571	0.0932927855973954	0.329005940697198
GO:0016853	isomerase activity	8/480	180/18639	0.0444444444444444	1.72583333333333	0.0944053390173531	0.331167935283096
GO:0140097	catalytic activity, acting on DNA	13/480	336/18639	0.0386904761904762	1.50239955357143	0.0956832278801467	0.333884105708091
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3/480	43/18639	0.0697674418604651	2.70915697674419	0.0984676716368968	0.341801394216035
GO:0051428	peptide hormone receptor binding	2/480	21/18639	0.0952380952380952	3.69821428571429	0.100803579037494	0.348087358863846
GO:0005506	iron ion binding	7/480	154/18639	0.0454545454545455	1.76505681818182	0.103551366452206	0.355723087864314
GO:0004386	helicase activity	7/480	155/18639	0.0451612903225806	1.75366935483871	0.106197877679814	0.362933984029467
GO:0140299	molecular sensor activity	4/480	71/18639	0.0563380281690141	2.18767605633803	0.110421634248937	0.375433556446386
GO:0051020	GTPase binding	12/480	315/18639	0.0380952380952381	1.47928571428571	0.115479558516898	0.390627282126037
GO:0000295	adenine nucleotide transmembrane transporter activity	2/480	23/18639	0.0869565217391304	3.37663043478261	0.117502265617677	0.39147739751015
GO:0017134	fibroblast growth factor binding	2/480	23/18639	0.0869565217391304	3.37663043478261	0.117502265617677	0.39147739751015
GO:0043274	phospholipase binding	2/480	23/18639	0.0869565217391304	3.37663043478261	0.117502265617677	0.39147739751015
GO:0043539	protein serine/threonine kinase activator activity	4/480	73/18639	0.0547945205479452	2.1277397260274	0.1190143567951	0.394532592775757
GO:0099106	ion channel regulator activity	7/480	160/18639	0.04375	1.6988671875	0.119967802646277	0.395714692310855
GO:0004866	endopeptidase inhibitor activity	7/480	161/18639	0.0434782608695652	1.6883152173913	0.122827602305926	0.403078473750813
GO:0048029	monosaccharide binding	4/480	74/18639	0.0540540540540541	2.09898648648649	0.123416184270611	0.403078473750813
GO:0140612	DNA damage sensor activity	2/480	24/18639	0.0833333333333333	3.2359375	0.126094204523429	0.409806164701143
GO:0035254	glutamate receptor binding	3/480	49/18639	0.0612244897959184	2.37742346938776	0.131770288349377	0.426164395978717
GO:0051536	iron-sulfur cluster binding	4/480	76/18639	0.0526315789473684	2.04375	0.132423426302826	0.426197726401815
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	2/480	25/18639	0.08	3.1065	0.134829487902674	0.431845171398419
GO:0002020	protease binding	6/480	136/18639	0.0441176470588235	1.71314338235294	0.139352657302569	0.44418659515194
GO:0004529	DNA exonuclease activity	2/480	26/18639	0.0769230769230769	2.98701923076923	0.143695076268397	0.449714463709349
GO:0015216	purine nucleotide transmembrane transporter activity	2/480	26/18639	0.0769230769230769	2.98701923076923	0.143695076268397	0.449714463709349
GO:0097602	cullin family protein binding	2/480	26/18639	0.0769230769230769	2.98701923076923	0.143695076268397	0.449714463709349
GO:0016247	channel regulator activity	7/480	168/18639	0.0416666666666667	1.61796875	0.143800100009626	0.449714463709349
GO:0141108	transporter regulator activity	7/480	170/18639	0.0411764705882353	1.59893382352941	0.150089287268652	0.467179330793972
GO:0004364	glutathione transferase activity	2/480	27/18639	0.0740740740740741	2.87638888888889	0.152678504131336	0.468638186292017
GO:0008266	poly(U) RNA binding	2/480	27/18639	0.0740740740740741	2.87638888888889	0.152678504131336	0.468638186292017
GO:0035255	ionotropic glutamate receptor binding	2/480	27/18639	0.0740740740740741	2.87638888888889	0.152678504131336	0.468638186292017
GO:0016860	intramolecular oxidoreductase activity	3/480	53/18639	0.0566037735849057	2.19799528301887	0.155853539894699	0.476179248618365
GO:0003714	transcription corepressor activity	8/480	204/18639	0.0392156862745098	1.52279411764706	0.157404337978732	0.47758447313612
GO:0016866	intramolecular transferase activity	2/480	28/18639	0.0714285714285714	2.77366071428571	0.16176785918638	0.47758447313612
GO:0019789	SUMO transferase activity	2/480	28/18639	0.0714285714285714	2.77366071428571	0.16176785918638	0.47758447313612
GO:0046625	sphingolipid binding	2/480	28/18639	0.0714285714285714	2.77366071428571	0.16176785918638	0.47758447313612
GO:0051537	2 iron, 2 sulfur cluster binding	2/480	28/18639	0.0714285714285714	2.77366071428571	0.16176785918638	0.47758447313612
GO:0015485	cholesterol binding	3/480	54/18639	0.0555555555555556	2.15729166666667	0.162076178666104	0.47758447313612
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	3/480	54/18639	0.0555555555555556	2.15729166666667	0.162076178666104	0.47758447313612
GO:0051287	NAD binding	3/480	54/18639	0.0555555555555556	2.15729166666667	0.162076178666104	0.47758447313612
GO:0140313	molecular sequestering activity	3/480	55/18639	0.0545454545454545	2.11806818181818	0.168372297656937	0.493941740471458
GO:0001221	transcription coregulator binding	5/480	115/18639	0.0434782608695652	1.6883152173913	0.175495315336496	0.512570017921131
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/480	30/18639	0.0666666666666667	2.58875	0.180219347484321	0.517252932390063
GO:0008187	poly-pyrimidine tract binding	2/480	30/18639	0.0666666666666667	2.58875	0.180219347484321	0.517252932390063
GO:0015215	nucleotide transmembrane transporter activity	2/480	30/18639	0.0666666666666667	2.58875	0.180219347484321	0.517252932390063
GO:0031210	phosphatidylcholine binding	2/480	30/18639	0.0666666666666667	2.58875	0.180219347484321	0.517252932390063
GO:0019209	kinase activator activity	6/480	148/18639	0.0405405405405405	1.57423986486487	0.183082249135273	0.523204875761579
GO:0017116	single-stranded DNA helicase activity	3/480	58/18639	0.0517241379310345	2.00851293103448	0.187665735273326	0.531719583274424
GO:0061980	regulatory RNA binding	3/480	58/18639	0.0517241379310345	2.00851293103448	0.187665735273326	0.531719583274424
GO:0031593	polyubiquitin modification-dependent protein binding	3/480	59/18639	0.0508474576271186	1.97447033898305	0.19422011610829	0.547948667999134
GO:0051059	NF-kappaB binding	2/480	32/18639	0.0625	2.426953125	0.198964558112707	0.558955517070868
GO:0022804	active transmembrane transporter activity	15/480	457/18639	0.0328227571115974	1.27454868708972	0.202473529471495	0.566413291306334
GO:0016836	hydro-lyase activity	3/480	61/18639	0.0491803278688525	1.90973360655738	0.207492862246622	0.572878564504229
GO:0140311	protein sequestering activity	2/480	33/18639	0.0606060606060606	2.35340909090909	0.208422853919662	0.572878564504229
GO:0015035	protein-disulfide reductase activity	2/480	34/18639	0.0588235294117647	2.28419117647059	0.217926138395805	0.572878564504229
GO:0019825	oxygen binding	2/480	34/18639	0.0588235294117647	2.28419117647059	0.217926138395805	0.572878564504229
GO:0034061	DNA polymerase activity	2/480	35/18639	0.0571428571428571	2.21892857142857	0.227465843886781	0.572878564504229
GO:0004867	serine-type endopeptidase inhibitor activity	4/480	95/18639	0.0421052631578947	1.635	0.229181048930802	0.572878564504229
GO:0001094	TFIID-class transcription factor complex binding	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0004090	carbonyl reductase (NADPH) activity	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0004955	prostaglandin receptor activity	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0005131	growth hormone receptor binding	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0005345	purine nucleobase transmembrane transporter activity	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0005522	profilin binding	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0005528	FK506 binding	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0016868	intramolecular phosphotransferase activity	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0032052	bile acid binding	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0032356	oxidized DNA binding	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0050815	phosphoserine residue binding	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0051880	G-quadruplex DNA binding	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0097177	mitochondrial ribosome binding	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0140940	histone H2A methyltransferase activity	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:1990259	histone H2AQ104 methyltransferase activity	1/480	10/18639	0.1	3.883125	0.229690102730884	0.572878564504229
GO:0004519	endonuclease activity	5/480	127/18639	0.0393700787401575	1.52878937007874	0.229842681988122	0.572878564504229
GO:0042826	histone deacetylase binding	5/480	127/18639	0.0393700787401575	1.52878937007874	0.229842681988122	0.572878564504229
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	5/480	128/18639	0.0390625	1.516845703125	0.234580824112996	0.575653544511547
GO:0004033	aldo-keto reductase (NADPH) activity	2/480	36/18639	0.0555555555555556	2.15729166666667	0.237033812445931	0.575653544511547
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/480	36/18639	0.0555555555555556	2.15729166666667	0.237033812445931	0.575653544511547
GO:0044390	ubiquitin-like protein conjugating enzyme binding	2/480	36/18639	0.0555555555555556	2.15729166666667	0.237033812445931	0.575653544511547
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	2/480	36/18639	0.0555555555555556	2.15729166666667	0.237033812445931	0.575653544511547
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	2/480	36/18639	0.0555555555555556	2.15729166666667	0.237033812445931	0.575653544511547
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	2/480	36/18639	0.0555555555555556	2.15729166666667	0.237033812445931	0.575653544511547
GO:0022829	wide pore channel activity	2/480	37/18639	0.0540540540540541	2.09898648648649	0.246622280488482	0.578474737329392
GO:0042805	actinin binding	2/480	37/18639	0.0540540540540541	2.09898648648649	0.246622280488482	0.578474737329392
GO:0004954	prostanoid receptor activity	1/480	11/18639	0.0909090909090909	3.53011363636364	0.249538121985228	0.578474737329392
GO:0008432	JUN kinase binding	1/480	11/18639	0.0909090909090909	3.53011363636364	0.249538121985228	0.578474737329392
GO:0015205	nucleobase transmembrane transporter activity	1/480	11/18639	0.0909090909090909	3.53011363636364	0.249538121985228	0.578474737329392
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/480	11/18639	0.0909090909090909	3.53011363636364	0.249538121985228	0.578474737329392
GO:0019206	nucleoside kinase activity	1/480	11/18639	0.0909090909090909	3.53011363636364	0.249538121985228	0.578474737329392
GO:0032404	mismatch repair complex binding	1/480	11/18639	0.0909090909090909	3.53011363636364	0.249538121985228	0.578474737329392
GO:0032794	GTPase activating protein binding	1/480	11/18639	0.0909090909090909	3.53011363636364	0.249538121985228	0.578474737329392
GO:0042608	T cell receptor binding	1/480	11/18639	0.0909090909090909	3.53011363636364	0.249538121985228	0.578474737329392
GO:0050998	nitric-oxide synthase binding	1/480	11/18639	0.0909090909090909	3.53011363636364	0.249538121985228	0.578474737329392
GO:0070697	activin receptor binding	1/480	11/18639	0.0909090909090909	3.53011363636364	0.249538121985228	0.578474737329392
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/480	11/18639	0.0909090909090909	3.53011363636364	0.249538121985228	0.578474737329392
GO:0032934	sterol binding	3/480	68/18639	0.0441176470588235	1.71314338235294	0.255318537266938	0.589812509435469
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	2/480	39/18639	0.0512820512820513	1.99134615384615	0.265831544015113	0.592241313304194
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	2/480	39/18639	0.0512820512820513	1.99134615384615	0.265831544015113	0.592241313304194
GO:0003720	telomerase activity	1/480	12/18639	0.0833333333333333	3.2359375	0.268875769690139	0.592241313304194
GO:0005049	nuclear export signal receptor activity	1/480	12/18639	0.0833333333333333	3.2359375	0.268875769690139	0.592241313304194
GO:0005527	macrolide binding	1/480	12/18639	0.0833333333333333	3.2359375	0.268875769690139	0.592241313304194
GO:0008179	adenylate cyclase binding	1/480	12/18639	0.0833333333333333	3.2359375	0.268875769690139	0.592241313304194
GO:0008603	cAMP-dependent protein kinase regulator activity	1/480	12/18639	0.0833333333333333	3.2359375	0.268875769690139	0.592241313304194
GO:0015368	calcium:monoatomic cation antiporter activity	1/480	12/18639	0.0833333333333333	3.2359375	0.268875769690139	0.592241313304194
GO:0016208	AMP binding	1/480	12/18639	0.0833333333333333	3.2359375	0.268875769690139	0.592241313304194
GO:0016840	carbon-nitrogen lyase activity	1/480	12/18639	0.0833333333333333	3.2359375	0.268875769690139	0.592241313304194
GO:0035259	nuclear glucocorticoid receptor binding	1/480	12/18639	0.0833333333333333	3.2359375	0.268875769690139	0.592241313304194
GO:0036009	protein-glutamine N-methyltransferase activity	1/480	12/18639	0.0833333333333333	3.2359375	0.268875769690139	0.592241313304194
GO:0097371	MDM2/MDM4 family protein binding	1/480	12/18639	0.0833333333333333	3.2359375	0.268875769690139	0.592241313304194
GO:1990459	transferrin receptor binding	1/480	12/18639	0.0833333333333333	3.2359375	0.268875769690139	0.592241313304194
GO:0050997	quaternary ammonium group binding	2/480	40/18639	0.05	1.9415625	0.275438653153689	0.602692498484806
GO:0071855	neuropeptide receptor binding	2/480	40/18639	0.05	1.9415625	0.275438653153689	0.602692498484806
GO:0042287	MHC protein binding	2/480	41/18639	0.0487804878048781	1.89420731707317	0.28503886186081	0.614553480347131
GO:0003964	RNA-directed DNA polymerase activity	1/480	13/18639	0.0769230769230769	2.98701923076923	0.287716142833895	0.614553480347131
GO:0008035	high-density lipoprotein particle binding	1/480	13/18639	0.0769230769230769	2.98701923076923	0.287716142833895	0.614553480347131
GO:0030955	potassium ion binding	1/480	13/18639	0.0769230769230769	2.98701923076923	0.287716142833895	0.614553480347131
GO:0035325	Toll-like receptor binding	1/480	13/18639	0.0769230769230769	2.98701923076923	0.287716142833895	0.614553480347131
GO:0043560	insulin receptor substrate binding	1/480	13/18639	0.0769230769230769	2.98701923076923	0.287716142833895	0.614553480347131
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/480	13/18639	0.0769230769230769	2.98701923076923	0.287716142833895	0.614553480347131
GO:0030295	protein kinase activator activity	5/480	139/18639	0.0359712230215827	1.39680755395683	0.288274709484099	0.614553480347131
GO:0004521	RNA endonuclease activity	3/480	73/18639	0.0410958904109589	1.59580479452055	0.290344186795797	0.616981396941069
GO:0016859	cis-trans isomerase activity	2/480	42/18639	0.0476190476190476	1.84910714285714	0.294626165673981	0.618155531145093
GO:0019894	kinesin binding	2/480	42/18639	0.0476190476190476	1.84910714285714	0.294626165673981	0.618155531145093
GO:0048487	beta-tubulin binding	2/480	42/18639	0.0476190476190476	1.84910714285714	0.294626165673981	0.618155531145093
GO:0051879	Hsp90 protein binding	2/480	42/18639	0.0476190476190476	1.84910714285714	0.294626165673981	0.618155531145093
GO:0020037	heme binding	5/480	142/18639	0.0352112676056338	1.36729753521127	0.303310384665908	0.626314006137335
GO:0004712	protein serine/threonine/tyrosine kinase activity	2/480	43/18639	0.0465116279069767	1.80610465116279	0.30419487270018	0.626314006137335
GO:0019003	GDP binding	3/480	75/18639	0.04	1.55325	0.304460445522949	0.626314006137335
GO:0033218	amide binding	8/480	247/18639	0.0323886639676113	1.25769230769231	0.305141178175761	0.626314006137335
GO:0008392	arachidonate epoxygenase activity	1/480	14/18639	0.0714285714285714	2.77366071428571	0.306072002999241	0.626314006137335
GO:0016530	metallochaperone activity	1/480	14/18639	0.0714285714285714	2.77366071428571	0.306072002999241	0.626314006137335
GO:0030983	mismatched DNA binding	1/480	14/18639	0.0714285714285714	2.77366071428571	0.306072002999241	0.626314006137335
GO:1901612	cardiolipin binding	1/480	14/18639	0.0714285714285714	2.77366071428571	0.306072002999241	0.626314006137335
GO:0016741	transferase activity, transferring one-carbon groups	7/480	215/18639	0.0325581395348837	1.26427325581395	0.318328158987187	0.639234182774252
GO:0008009	chemokine activity	2/480	45/18639	0.0444444444444444	1.72583333333333	0.323255219722054	0.639234182774252
GO:0051539	4 iron, 4 sulfur cluster binding	2/480	45/18639	0.0444444444444444	1.72583333333333	0.323255219722054	0.639234182774252
GO:0000774	adenyl-nucleotide exchange factor activity	1/480	15/18639	0.0666666666666667	2.58875	0.323955784935368	0.639234182774252
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/480	15/18639	0.0666666666666667	2.58875	0.323955784935368	0.639234182774252
GO:0004953	icosanoid receptor activity	1/480	15/18639	0.0666666666666667	2.58875	0.323955784935368	0.639234182774252
GO:0016846	carbon-sulfur lyase activity	1/480	15/18639	0.0666666666666667	2.58875	0.323955784935368	0.639234182774252
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/480	15/18639	0.0666666666666667	2.58875	0.323955784935368	0.639234182774252
GO:0031005	filamin binding	1/480	15/18639	0.0666666666666667	2.58875	0.323955784935368	0.639234182774252
GO:0050780	dopamine receptor binding	1/480	15/18639	0.0666666666666667	2.58875	0.323955784935368	0.639234182774252
GO:0051371	muscle alpha-actinin binding	1/480	15/18639	0.0666666666666667	2.58875	0.323955784935368	0.639234182774252
GO:0061578	K63-linked deubiquitinase activity	1/480	15/18639	0.0666666666666667	2.58875	0.323955784935368	0.639234182774252
GO:0033293	monocarboxylic acid binding	3/480	79/18639	0.0379746835443038	1.47460443037975	0.33275759165058	0.653790932104881
GO:0000062	fatty-acyl-CoA binding	1/480	16/18639	0.0625	2.426953125	0.34137960491126	0.653790932104881
GO:0003688	DNA replication origin binding	1/480	16/18639	0.0625	2.426953125	0.34137960491126	0.653790932104881
GO:0004708	MAP kinase kinase activity	1/480	16/18639	0.0625	2.426953125	0.34137960491126	0.653790932104881
GO:0008296	3'-5'-DNA exonuclease activity	1/480	16/18639	0.0625	2.426953125	0.34137960491126	0.653790932104881
GO:0008391	arachidonate monooxygenase activity	1/480	16/18639	0.0625	2.426953125	0.34137960491126	0.653790932104881
GO:0016722	oxidoreductase activity, acting on metal ions	1/480	16/18639	0.0625	2.426953125	0.34137960491126	0.653790932104881
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/480	16/18639	0.0625	2.426953125	0.34137960491126	0.653790932104881
GO:0034450	ubiquitin-ubiquitin ligase activity	1/480	16/18639	0.0625	2.426953125	0.34137960491126	0.653790932104881
GO:0005504	fatty acid binding	2/480	47/18639	0.0425531914893617	1.65239361702128	0.34218017110165	0.653790932104881
GO:0043495	protein-membrane adaptor activity	2/480	47/18639	0.0425531914893617	1.65239361702128	0.34218017110165	0.653790932104881
GO:0101005	deubiquitinase activity	4/480	115/18639	0.0347826086956522	1.35065217391304	0.343978581848533	0.655338505073498
GO:0031406	carboxylic acid binding	6/480	187/18639	0.0320855614973262	1.24592245989305	0.351116671677264	0.659227047821302
GO:0016879	ligase activity, forming carbon-nitrogen bonds	2/480	48/18639	0.0416666666666667	1.61796875	0.351580634260797	0.659227047821302
GO:0046906	tetrapyrrole binding	5/480	152/18639	0.0328947368421053	1.27734375	0.354117398480969	0.659227047821302
GO:0005092	GDP-dissociation inhibitor activity	1/480	17/18639	0.0588235294117647	2.28419117647059	0.358355268855984	0.659227047821302
GO:0016018	cyclosporin A binding	1/480	17/18639	0.0588235294117647	2.28419117647059	0.358355268855984	0.659227047821302
GO:0032183	SUMO binding	1/480	17/18639	0.0588235294117647	2.28419117647059	0.358355268855984	0.659227047821302
GO:0036041	long-chain fatty acid binding	1/480	17/18639	0.0588235294117647	2.28419117647059	0.358355268855984	0.659227047821302
GO:0048038	quinone binding	1/480	17/18639	0.0588235294117647	2.28419117647059	0.358355268855984	0.659227047821302
GO:0070402	NADPH binding	1/480	17/18639	0.0588235294117647	2.28419117647059	0.358355268855984	0.659227047821302
GO:0070403	NAD+ binding	1/480	17/18639	0.0588235294117647	2.28419117647059	0.358355268855984	0.659227047821302
GO:1901567	fatty acid derivative binding	1/480	17/18639	0.0588235294117647	2.28419117647059	0.358355268855984	0.659227047821302
GO:0003774	cytoskeletal motor activity	5/480	153/18639	0.0326797385620915	1.26899509803922	0.359231546529301	0.659227047821302
GO:0043177	organic acid binding	6/480	189/18639	0.0317460317460317	1.2327380952381	0.360292821323569	0.659227047821302
GO:0001222	transcription corepressor binding	2/480	49/18639	0.0408163265306122	1.58494897959184	0.360934266001708	0.659227047821302
GO:0060590	ATPase regulator activity	2/480	49/18639	0.0408163265306122	1.58494897959184	0.360934266001708	0.659227047821302
GO:0004527	exonuclease activity	3/480	84/18639	0.0357142857142857	1.38683035714286	0.368051127464686	0.664585315061915
GO:0004860	protein kinase inhibitor activity	3/480	84/18639	0.0357142857142857	1.38683035714286	0.368051127464686	0.664585315061915
GO:0051117	ATPase binding	3/480	84/18639	0.0357142857142857	1.38683035714286	0.368051127464686	0.664585315061915
GO:0015605	organophosphate ester transmembrane transporter activity	2/480	50/18639	0.04	1.55325	0.37023724691268	0.664585315061915
GO:0008409	5'-3' exonuclease activity	1/480	18/18639	0.0555555555555556	2.15729166666667	0.374894280291337	0.664585315061915
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/480	18/18639	0.0555555555555556	2.15729166666667	0.374894280291337	0.664585315061915
GO:0017128	phospholipid scramblase activity	1/480	18/18639	0.0555555555555556	2.15729166666667	0.374894280291337	0.664585315061915
GO:0034185	apolipoprotein binding	1/480	18/18639	0.0555555555555556	2.15729166666667	0.374894280291337	0.664585315061915
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/480	18/18639	0.0555555555555556	2.15729166666667	0.374894280291337	0.664585315061915
GO:0070064	proline-rich region binding	1/480	18/18639	0.0555555555555556	2.15729166666667	0.374894280291337	0.664585315061915
GO:1901611	phosphatidylglycerol binding	1/480	18/18639	0.0555555555555556	2.15729166666667	0.374894280291337	0.664585315061915
GO:0016830	carbon-carbon lyase activity	2/480	51/18639	0.0392156862745098	1.52279411764706	0.379485984496054	0.670931220589024
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	2/480	52/18639	0.0384615384615385	1.49350961538462	0.388677104056395	0.682205798066315
GO:0031420	alkali metal ion binding	1/480	19/18639	0.0526315789473684	2.04375	0.391007848062141	0.682205798066315
GO:0050145	nucleoside monophosphate kinase activity	1/480	19/18639	0.0526315789473684	2.04375	0.391007848062141	0.682205798066315
GO:0070003	threonine-type peptidase activity	1/480	19/18639	0.0526315789473684	2.04375	0.391007848062141	0.682205798066315
GO:0120227	acyl-CoA binding	1/480	19/18639	0.0526315789473684	2.04375	0.391007848062141	0.682205798066315
GO:0004864	protein phosphatase inhibitor activity	2/480	53/18639	0.0377358490566038	1.46533018867925	0.397807439905873	0.69043542580522
GO:1901505	carbohydrate derivative transmembrane transporter activity	2/480	53/18639	0.0377358490566038	1.46533018867925	0.397807439905873	0.69043542580522
GO:0016408	C-acyltransferase activity	1/480	20/18639	0.05	1.9415625	0.406706893869347	0.697047751470822
GO:0030627	pre-mRNA 5'-splice site binding	1/480	20/18639	0.05	1.9415625	0.406706893869347	0.697047751470822
GO:0030742	GTP-dependent protein binding	1/480	20/18639	0.05	1.9415625	0.406706893869347	0.697047751470822
GO:0140664	ATP-dependent DNA damage sensor activity	1/480	20/18639	0.05	1.9415625	0.406706893869347	0.697047751470822
GO:0050661	NADP binding	2/480	54/18639	0.037037037037037	1.43819444444444	0.406874026876634	0.697047751470822
GO:0019210	kinase inhibitor activity	3/480	90/18639	0.0333333333333333	1.294375	0.409934474563517	0.70028789767222
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	10/480	349/18639	0.0286532951289398	1.11264326647564	0.410877816281287	0.70028789767222
GO:0019783	ubiquitin-like protein peptidase activity	4/480	127/18639	0.031496062992126	1.22303149606299	0.414112612693312	0.70399144157863
GO:0001846	opsonin binding	1/480	21/18639	0.0476190476190476	1.84910714285714	0.422002059610939	0.713743279392992
GO:0061891	calcium ion sensor activity	1/480	21/18639	0.0476190476190476	1.84910714285714	0.422002059610939	0.713743279392992
GO:0043178	alcohol binding	3/480	92/18639	0.0326086956521739	1.26623641304348	0.42371638665366	0.714819247713427
GO:0019212	phosphatase inhibitor activity	2/480	56/18639	0.0357142857142857	1.38683035714286	0.424805047254354	0.714836919618368
GO:0015932	nucleobase-containing compound transmembrane transporter activity	2/480	57/18639	0.0350877192982456	1.3625	0.433664480638014	0.725982864002713
GO:0008649	rRNA methyltransferase activity	1/480	22/18639	0.0454545454545455	1.76505681818182	0.436903714535569	0.725982864002713
GO:0016881	acid-amino acid ligase activity	1/480	22/18639	0.0454545454545455	1.76505681818182	0.436903714535569	0.725982864002713
GO:0031683	G-protein beta/gamma-subunit complex binding	1/480	22/18639	0.0454545454545455	1.76505681818182	0.436903714535569	0.725982864002713
GO:0140784	metal ion sensor activity	1/480	22/18639	0.0454545454545455	1.76505681818182	0.436903714535569	0.725982864002713
GO:0008408	3'-5' exonuclease activity	2/480	58/18639	0.0344827586206897	1.33900862068965	0.442450150115324	0.727996903726891
GO:0008276	protein methyltransferase activity	3/480	95/18639	0.0315789473684211	1.22625	0.444175753737393	0.727996903726891
GO:0031267	small GTPase binding	8/480	283/18639	0.0282685512367491	1.09770318021201	0.444959427056115	0.727996903726891
GO:0015459	potassium channel regulator activity	2/480	59/18639	0.0338983050847458	1.31631355932203	0.451159975869957	0.727996903726891
GO:0036002	pre-mRNA binding	2/480	59/18639	0.0338983050847458	1.31631355932203	0.451159975869957	0.727996903726891
GO:0045309	protein phosphorylated amino acid binding	2/480	59/18639	0.0338983050847458	1.31631355932203	0.451159975869957	0.727996903726891
GO:0003887	DNA-directed DNA polymerase activity	1/480	23/18639	0.0434782608695652	1.6883152173913	0.451421962213655	0.727996903726891
GO:0005158	insulin receptor binding	1/480	23/18639	0.0434782608695652	1.6883152173913	0.451421962213655	0.727996903726891
GO:0031681	G-protein beta-subunit binding	1/480	23/18639	0.0434782608695652	1.6883152173913	0.451421962213655	0.727996903726891
GO:0099186	structural constituent of postsynapse	1/480	23/18639	0.0434782608695652	1.6883152173913	0.451421962213655	0.727996903726891
GO:0140102	catalytic activity, acting on a rRNA	1/480	23/18639	0.0434782608695652	1.6883152173913	0.451421962213655	0.727996903726891
GO:0004518	nuclease activity	6/480	209/18639	0.0287081339712919	1.11477272727273	0.452011633814902	0.727996903726891
GO:0008094	ATP-dependent activity, acting on DNA	6/480	210/18639	0.0285714285714286	1.10946428571429	0.45654720096139	0.727996903726891
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	2/480	60/18639	0.0333333333333333	1.294375	0.459792033591284	0.727996903726891
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/480	60/18639	0.0333333333333333	1.294375	0.459792033591284	0.727996903726891
GO:0140030	modification-dependent protein binding	5/480	173/18639	0.0289017341040462	1.12229046242775	0.460883893167854	0.727996903726891
GO:0140104	molecular carrier activity	7/480	249/18639	0.0281124497991968	1.09164156626506	0.460896743932906	0.727996903726891
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/480	24/18639	0.0416666666666667	1.61796875	0.465566647330621	0.727996903726891
GO:0005315	phosphate transmembrane transporter activity	1/480	24/18639	0.0416666666666667	1.61796875	0.465566647330621	0.727996903726891
GO:0005540	hyaluronic acid binding	1/480	24/18639	0.0416666666666667	1.61796875	0.465566647330621	0.727996903726891
GO:0015149	hexose transmembrane transporter activity	1/480	24/18639	0.0416666666666667	1.61796875	0.465566647330621	0.727996903726891
GO:0015295	solute:proton symporter activity	1/480	24/18639	0.0416666666666667	1.61796875	0.465566647330621	0.727996903726891
GO:0035035	histone acetyltransferase binding	1/480	24/18639	0.0416666666666667	1.61796875	0.465566647330621	0.727996903726891
GO:0055056	D-glucose transmembrane transporter activity	1/480	24/18639	0.0416666666666667	1.61796875	0.465566647330621	0.727996903726891
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/480	24/18639	0.0416666666666667	1.61796875	0.465566647330621	0.727996903726891
GO:0001848	complement binding	1/480	25/18639	0.04	1.55325	0.479347362306786	0.744279393933019
GO:0008139	nuclear localization sequence binding	1/480	25/18639	0.04	1.55325	0.479347362306786	0.744279393933019
GO:0017056	structural constituent of nuclear pore	1/480	25/18639	0.04	1.55325	0.479347362306786	0.744279393933019
GO:0008157	protein phosphatase 1 binding	1/480	26/18639	0.0384615384615385	1.49350961538462	0.492773453748321	0.754523787148123
GO:0008198	ferrous iron binding	1/480	26/18639	0.0384615384615385	1.49350961538462	0.492773453748321	0.754523787148123
GO:0015145	monosaccharide transmembrane transporter activity	1/480	26/18639	0.0384615384615385	1.49350961538462	0.492773453748321	0.754523787148123
GO:0050681	nuclear androgen receptor binding	1/480	26/18639	0.0384615384615385	1.49350961538462	0.492773453748321	0.754523787148123
GO:0050750	low-density lipoprotein particle receptor binding	1/480	26/18639	0.0384615384615385	1.49350961538462	0.492773453748321	0.754523787148123
GO:0051139	metal cation:proton antiporter activity	1/480	26/18639	0.0384615384615385	1.49350961538462	0.492773453748321	0.754523787148123
GO:0005253	monoatomic anion channel activity	3/480	103/18639	0.029126213592233	1.1310072815534	0.497216503019116	0.759572676271139
GO:0001671	ATPase activator activity	1/480	27/18639	0.037037037037037	1.43819444444444	0.50585402873359	0.763966334966675
GO:0004683	calcium/calmodulin-dependent protein kinase activity	1/480	27/18639	0.037037037037037	1.43819444444444	0.50585402873359	0.763966334966675
GO:0008395	steroid hydroxylase activity	1/480	27/18639	0.037037037037037	1.43819444444444	0.50585402873359	0.763966334966675
GO:0015252	proton channel activity	1/480	27/18639	0.037037037037037	1.43819444444444	0.50585402873359	0.763966334966675
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/480	27/18639	0.037037037037037	1.43819444444444	0.50585402873359	0.763966334966675
GO:0051119	sugar transmembrane transporter activity	1/480	28/18639	0.0357142857142857	1.38683035714286	0.518597960939042	0.777896941408563
GO:0051393	alpha-actinin binding	1/480	28/18639	0.0357142857142857	1.38683035714286	0.518597960939042	0.777896941408563
GO:0051959	dynein light intermediate chain binding	1/480	28/18639	0.0357142857142857	1.38683035714286	0.518597960939042	0.777896941408563
GO:0005496	steroid binding	3/480	108/18639	0.0277777777777778	1.07864583333333	0.529045490206323	0.78761121577542
GO:0003785	actin monomer binding	1/480	29/18639	0.0344827586206897	1.33900862068965	0.531013896608768	0.78761121577542
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/480	29/18639	0.0344827586206897	1.33900862068965	0.531013896608768	0.78761121577542
GO:0043236	laminin binding	1/480	29/18639	0.0344827586206897	1.33900862068965	0.531013896608768	0.78761121577542
GO:0097472	cyclin-dependent protein kinase activity	1/480	29/18639	0.0344827586206897	1.33900862068965	0.531013896608768	0.78761121577542
GO:0001965	G-protein alpha-subunit binding	1/480	30/18639	0.0333333333333333	1.294375	0.54311026037168	0.796641819969964
GO:0016769	transferase activity, transferring nitrogenous groups	1/480	30/18639	0.0333333333333333	1.294375	0.54311026037168	0.796641819969964
GO:0033612	receptor serine/threonine kinase binding	1/480	30/18639	0.0333333333333333	1.294375	0.54311026037168	0.796641819969964
GO:0035925	mRNA 3'-UTR AU-rich region binding	1/480	30/18639	0.0333333333333333	1.294375	0.54311026037168	0.796641819969964
GO:0098918	structural constituent of synapse	1/480	30/18639	0.0333333333333333	1.294375	0.54311026037168	0.796641819969964
GO:0005184	neuropeptide hormone activity	1/480	31/18639	0.032258064516129	1.25262096774194	0.554895260910215	0.80678850434972
GO:0008327	methyl-CpG binding	1/480	31/18639	0.032258064516129	1.25262096774194	0.554895260910215	0.80678850434972
GO:0047499	calcium-independent phospholipase A2 activity	1/480	31/18639	0.032258064516129	1.25262096774194	0.554895260910215	0.80678850434972
GO:0070325	lipoprotein particle receptor binding	1/480	31/18639	0.032258064516129	1.25262096774194	0.554895260910215	0.80678850434972
GO:0042379	chemokine receptor binding	2/480	72/18639	0.0277777777777778	1.07864583333333	0.556795607803645	0.807780061211853
GO:0047498	calcium-dependent phospholipase A2 activity	1/480	32/18639	0.03125	1.2134765625	0.566376896484328	0.814550720974207
GO:0071813	lipoprotein particle binding	1/480	32/18639	0.03125	1.2134765625	0.566376896484328	0.814550720974207
GO:0071814	protein-lipid complex binding	1/480	32/18639	0.03125	1.2134765625	0.566376896484328	0.814550720974207
GO:0160041	neuropeptide activity	1/480	32/18639	0.03125	1.2134765625	0.566376896484328	0.814550720974207
GO:0017124	SH3 domain binding	3/480	115/18639	0.0260869565217391	1.01298913043478	0.571650489156803	0.818676518404704
GO:0035064	methylated histone binding	2/480	74/18639	0.027027027027027	1.04949324324324	0.571715276050344	0.818676518404704
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/480	33/18639	0.0303030303030303	1.17670454545455	0.577562960314473	0.821725842679176
GO:0019956	chemokine binding	1/480	33/18639	0.0303030303030303	1.17670454545455	0.577562960314473	0.821725842679176
GO:0071889	14-3-3 protein binding	1/480	33/18639	0.0303030303030303	1.17670454545455	0.577562960314473	0.821725842679176
GO:0140034	methylation-dependent protein binding	2/480	76/18639	0.0263157894736842	1.021875	0.586267241504221	0.831875636211956
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/480	34/18639	0.0294117647058824	1.14209558823529	0.58846104582716	0.831875636211956
GO:0016831	carboxy-lyase activity	1/480	34/18639	0.0294117647058824	1.14209558823529	0.58846104582716	0.831875636211956
GO:0004623	phospholipase A2 activity	1/480	35/18639	0.0285714285714286	1.10946428571429	0.599078551766583	0.843288916817929
GO:0005154	epidermal growth factor receptor binding	1/480	35/18639	0.0285714285714286	1.10946428571429	0.599078551766583	0.843288916817929
GO:0004540	RNA nuclease activity	3/480	121/18639	0.0247933884297521	0.96275826446281	0.606209837620893	0.850351455999615
GO:0008168	methyltransferase activity	5/480	204/18639	0.0245098039215686	0.951746323529412	0.606660993495954	0.850351455999615
GO:0019213	deacetylase activity	1/480	37/18639	0.027027027027027	1.04949324324324	0.619500476250391	0.852473700338251
GO:0001618	virus receptor activity	2/480	81/18639	0.0246913580246914	0.958796296296296	0.621032876717006	0.852473700338251
GO:0033192	calmodulin-dependent protein phosphatase activity	2/480	81/18639	0.0246913580246914	0.958796296296296	0.621032876717006	0.852473700338251
GO:0140791	histone H2AXS140 phosphatase activity	2/480	81/18639	0.0246913580246914	0.958796296296296	0.621032876717006	0.852473700338251
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	2/480	81/18639	0.0246913580246914	0.958796296296296	0.621032876717006	0.852473700338251
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	2/480	81/18639	0.0246913580246914	0.958796296296296	0.621032876717006	0.852473700338251
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	2/480	81/18639	0.0246913580246914	0.958796296296296	0.621032876717006	0.852473700338251
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	2/480	81/18639	0.0246913580246914	0.958796296296296	0.621032876717006	0.852473700338251
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	2/480	81/18639	0.0246913580246914	0.958796296296296	0.621032876717006	0.852473700338251
GO:1990439	MAP kinase serine/threonine phosphatase activity	2/480	81/18639	0.0246913580246914	0.958796296296296	0.621032876717006	0.852473700338251
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	2/480	82/18639	0.024390243902439	0.947103658536585	0.627709698408827	0.856320020668832
GO:0033549	MAP kinase phosphatase activity	2/480	82/18639	0.024390243902439	0.947103658536585	0.627709698408827	0.856320020668832
GO:0140272	exogenous protein binding	2/480	82/18639	0.024390243902439	0.947103658536585	0.627709698408827	0.856320020668832
GO:0000146	microfilament motor activity	1/480	38/18639	0.0263157894736842	1.021875	0.629318763069002	0.856752238017964
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	2/480	83/18639	0.0240963855421687	0.935692771084337	0.634294841992492	0.861757131641439
GO:0017018	myosin phosphatase activity	2/480	84/18639	0.0238095238095238	0.924553571428571	0.640788591127317	0.868799255454828
GO:0001664	G protein-coupled receptor binding	7/480	297/18639	0.0235690235690236	0.915214646464646	0.646443367774025	0.871721723962976
GO:0015144	carbohydrate transmembrane transporter activity	1/480	40/18639	0.025	0.97078125	0.648203333203238	0.871721723962976
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/480	40/18639	0.025	0.97078125	0.648203333203238	0.871721723962976
GO:0030331	nuclear estrogen receptor binding	1/480	40/18639	0.025	0.97078125	0.648203333203238	0.871721723962976
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	2/480	86/18639	0.0232558139534884	0.903052325581395	0.653503268767023	0.876817426612169
GO:0017080	sodium channel regulator activity	1/480	41/18639	0.024390243902439	0.947103658536585	0.657282444986799	0.876817426612169
GO:0042169	SH2 domain binding	1/480	41/18639	0.024390243902439	0.947103658536585	0.657282444986799	0.876817426612169
GO:0140828	metal cation:monoatomic cation antiporter activity	1/480	41/18639	0.024390243902439	0.947103658536585	0.657282444986799	0.876817426612169
GO:0004721	phosphoprotein phosphatase activity	4/480	175/18639	0.0228571428571429	0.887571428571429	0.6633292706705	0.883031065954307
GO:0005179	hormone activity	3/480	132/18639	0.0227272727272727	0.882528409090909	0.664604075280843	0.883031065954307
GO:0048156	tau protein binding	1/480	43/18639	0.0232558139534884	0.903052325581395	0.674745168839414	0.894712093881063
GO:0015297	antiporter activity	3/480	135/18639	0.0222222222222222	0.862916666666667	0.679392636001169	0.896509112203751
GO:0001046	core promoter sequence-specific DNA binding	1/480	44/18639	0.0227272727272727	0.882528409090909	0.683140647380879	0.896509112203751
GO:0001223	transcription coactivator binding	1/480	44/18639	0.0227272727272727	0.882528409090909	0.683140647380879	0.896509112203751
GO:0016790	thiolester hydrolase activity	1/480	44/18639	0.0227272727272727	0.882528409090909	0.683140647380879	0.896509112203751
GO:0016779	nucleotidyltransferase activity	3/480	136/18639	0.0220588235294118	0.856571691176471	0.684213590912667	0.896509112203751
GO:0140789	histone phosphatase activity	3/480	136/18639	0.0220588235294118	0.856571691176471	0.684213590912667	0.896509112203751
GO:0016922	nuclear receptor binding	3/480	137/18639	0.0218978102189781	0.850319343065693	0.688980363110122	0.899874382641091
GO:0052689	carboxylic ester hydrolase activity	2/480	92/18639	0.0217391304347826	0.844157608695652	0.689496510379599	0.899874382641091
GO:0140303	intramembrane lipid transporter activity	1/480	45/18639	0.0222222222222222	0.862916666666667	0.691319861645852	0.900481470080943
GO:0019787	ubiquitin-like protein transferase activity	11/480	479/18639	0.022964509394572	0.891740605427975	0.69294482806626	0.900828276486138
GO:0051219	phosphoprotein binding	2/480	93/18639	0.021505376344086	0.83508064516129	0.69518728712985	0.90197489504323
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/480	46/18639	0.0217391304347826	0.844157608695652	0.699288371187101	0.902000369838615
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/480	46/18639	0.0217391304347826	0.844157608695652	0.699288371187101	0.902000369838615
GO:0030291	protein serine/threonine kinase inhibitor activity	1/480	46/18639	0.0217391304347826	0.844157608695652	0.699288371187101	0.902000369838615
GO:0045182	translation regulator activity	8/480	356/18639	0.0224719101123595	0.872612359550562	0.70093597925094	0.90237000823956
GO:0001784	phosphotyrosine residue binding	1/480	47/18639	0.0212765957446809	0.826196808510638	0.707051592928089	0.908479081611091
GO:0140693	molecular condensate scaffold activity	1/480	48/18639	0.0208333333333333	0.808984375	0.714614804814627	0.915073236116219
GO:1901681	sulfur compound binding	6/480	275/18639	0.0218181818181818	0.847227272727273	0.714944096995779	0.915073236116219
GO:0016763	pentosyltransferase activity	1/480	49/18639	0.0204081632653061	0.792474489795918	0.72198314937323	0.922302173476785
GO:0005125	cytokine activity	5/480	234/18639	0.0213675213675214	0.829727564102564	0.723615980440346	0.922610375061441
GO:0016755	aminoacyltransferase activity	11/480	496/18639	0.0221774193548387	0.861176915322581	0.734984360586053	0.934709700981544
GO:0005048	signal sequence binding	1/480	51/18639	0.0196078431372549	0.761397058823529	0.736155150232197	0.934709700981544
GO:0005543	phospholipid binding	11/480	497/18639	0.0221327967806841	0.85944416498994	0.737335103489212	0.934709700981544
GO:0008509	monoatomic anion transmembrane transporter activity	3/480	149/18639	0.0201342281879195	0.781837248322148	0.742004712392534	0.936686802687181
GO:0005080	protein kinase C binding	1/480	52/18639	0.0192307692307692	0.746754807692308	0.742968445255252	0.936686802687181
GO:0019842	vitamin binding	3/480	150/18639	0.02	0.776625	0.746081208100531	0.936686802687181
GO:0004722	protein serine/threonine phosphatase activity	2/480	103/18639	0.0194174757281553	0.754004854368932	0.747459249889596	0.936686802687181
GO:0017046	peptide hormone binding	1/480	53/18639	0.0188679245283019	0.732665094339623	0.749606156896586	0.936686802687181
GO:0051018	protein kinase A binding	1/480	53/18639	0.0188679245283019	0.732665094339623	0.749606156896586	0.936686802687181
GO:0140296	general transcription initiation factor binding	1/480	53/18639	0.0188679245283019	0.732665094339623	0.749606156896586	0.936686802687181
GO:0005539	glycosaminoglycan binding	5/480	242/18639	0.0206611570247934	0.802298553719008	0.750197122514168	0.936686802687181
GO:0004497	monooxygenase activity	2/480	106/18639	0.0188679245283019	0.732665094339623	0.761566462315458	0.948317356689924
GO:0008374	O-acyltransferase activity	1/480	55/18639	0.0181818181818182	0.706022727272727	0.762372776946801	0.948317356689924
GO:0035402	histone H3T11 kinase activity	5/480	247/18639	0.0202429149797571	0.786057692307692	0.765821784307198	0.950823676021859
GO:0030170	pyridoxal phosphate binding	1/480	56/18639	0.0178571428571429	0.693415178571429	0.768510372032119	0.952378274125784
GO:0004843	cysteine-type deubiquitinase activity	2/480	108/18639	0.0185185185185185	0.719097222222222	0.770587998476633	0.953171348861955
GO:0070279	vitamin B6 binding	1/480	57/18639	0.0175438596491228	0.68125	0.77448976294987	0.956213617943695
GO:1902936	phosphatidylinositol bisphosphate binding	2/480	111/18639	0.018018018018018	0.699662162162162	0.783562583281146	0.964663643731402
GO:0070063	RNA polymerase binding	1/480	59/18639	0.0169491525423729	0.658156779661017	0.785990106271345	0.964663643731402
GO:0005178	integrin binding	3/480	161/18639	0.0186335403726708	0.723563664596273	0.787591786758514	0.964663643731402
GO:0004674	protein serine/threonine kinase activity	9/480	433/18639	0.0207852193995381	0.807116050808314	0.787768380859184	0.964663643731402
GO:0008083	growth factor activity	3/480	162/18639	0.0185185185185185	0.719097222222222	0.791071359993897	0.964663643731402
GO:0001098	basal transcription machinery binding	1/480	60/18639	0.0166666666666667	0.6471875	0.791518887164227	0.964663643731402
GO:0001099	basal RNA polymerase II transcription machinery binding	1/480	60/18639	0.0166666666666667	0.6471875	0.791518887164227	0.964663643731402
GO:0019905	syntaxin binding	1/480	61/18639	0.0163934426229508	0.636577868852459	0.796905126152395	0.969446052548693
GO:0035401	histone H3Y41 kinase activity	2/480	115/18639	0.0173913043478261	0.675326086956522	0.799857708277345	0.969480183890091
GO:0140801	histone H2AXY142 kinase activity	2/480	115/18639	0.0173913043478261	0.675326086956522	0.799857708277345	0.969480183890091
GO:0005507	copper ion binding	1/480	63/18639	0.0158730158730159	0.616369047619048	0.807264554290602	0.971956930807238
GO:1990782	protein tyrosine kinase binding	2/480	117/18639	0.0170940170940171	0.663782051282051	0.807590746436866	0.971956930807238
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	3/480	167/18639	0.0179640718562874	0.697567365269461	0.80776511142502	0.971956930807238
GO:0016874	ligase activity	3/480	167/18639	0.0179640718562874	0.697567365269461	0.80776511142502	0.971956930807238
GO:0160215	deacylase activity	1/480	65/18639	0.0153846153846154	0.597403846153846	0.817096615150945	0.978431842452233
GO:0035173	histone kinase activity	7/480	360/18639	0.0194444444444444	0.755052083333333	0.822952337418897	0.978431842452233
GO:0008201	heparin binding	3/480	172/18639	0.0174418604651163	0.677289244186046	0.823321707239617	0.978431842452233
GO:0106310	protein serine kinase activity	7/480	361/18639	0.0193905817174515	0.752960526315789	0.825078943858533	0.978431842452233
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	2/480	122/18639	0.0163934426229508	0.636577868852459	0.825771161468405	0.978431842452233
GO:0008173	RNA methyltransferase activity	1/480	67/18639	0.0149253731343284	0.579570895522388	0.826428102222097	0.978431842452233
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/480	67/18639	0.0149253731343284	0.579570895522388	0.826428102222097	0.978431842452233
GO:0042054	histone methyltransferase activity	1/480	67/18639	0.0149253731343284	0.579570895522388	0.826428102222097	0.978431842452233
GO:0050840	extracellular matrix binding	1/480	67/18639	0.0149253731343284	0.579570895522388	0.826428102222097	0.978431842452233
GO:0003777	microtubule motor activity	1/480	68/18639	0.0147058823529412	0.571047794117647	0.830914130163805	0.980242114410324
GO:0005548	phospholipid transporter activity	1/480	68/18639	0.0147058823529412	0.571047794117647	0.830914130163805	0.980242114410324
GO:0002039	p53 binding	1/480	69/18639	0.0144927536231884	0.562771739130435	0.835284450422346	0.983647585488482
GO:0016798	hydrolase activity, acting on glycosyl bonds	2/480	130/18639	0.0153846153846154	0.597403846153846	0.851664436936597	0.988526917631426
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	2/480	130/18639	0.0153846153846154	0.597403846153846	0.851664436936597	0.988526917631426
GO:0008237	metallopeptidase activity	3/480	184/18639	0.016304347826087	0.633118206521739	0.856328654439869	0.988526917631426
GO:0019838	growth factor binding	2/480	136/18639	0.0147058823529412	0.571047794117647	0.868731553191977	0.988526917631426
GO:0019902	phosphatase binding	3/480	190/18639	0.0157894736842105	0.613125	0.870717284503594	0.988526917631426
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	4/480	243/18639	0.0164609053497942	0.639197530864198	0.875317953724769	0.988526917631426
GO:0140767	enzyme-substrate adaptor activity	2/480	139/18639	0.0143884892086331	0.558723021582734	0.876572113044297	0.988526917631426
GO:0004713	protein tyrosine kinase activity	2/480	140/18639	0.0142857142857143	0.554732142857143	0.87908828044906	0.988526917631426
GO:0004676	3-phosphoinositide-dependent protein kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0004711	ribosomal protein S6 kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0035175	histone H3S10 kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0035979	histone H2AXS139 kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0044022	histone H3S28 kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0044023	histone H4S1 kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0044024	histone H2AS1 kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0044025	histone H2BS14 kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0072354	histone H3T3 kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0072371	histone H2AS121 kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0072518	Rho-dependent protein serine/threonine kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0140823	histone H2BS36 kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0140855	histone H3S57 kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0140995	histone H2A kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0140997	histone H4 kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0140998	histone H2B kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:1990244	histone H2AT120 kinase activity	4/480	245/18639	0.0163265306122449	0.633979591836735	0.879250075850405	0.988526917631426
GO:0030971	receptor tyrosine kinase binding	1/480	81/18639	0.0123456790123457	0.479398148148148	0.879714415248982	0.988526917631426
GO:0004677	DNA-dependent protein kinase activity	4/480	246/18639	0.016260162601626	0.63140243902439	0.88117557816014	0.988526917631426
GO:0140857	histone H3T45 kinase activity	4/480	246/18639	0.016260162601626	0.63140243902439	0.88117557816014	0.988526917631426
GO:0035403	histone H3T6 kinase activity	4/480	247/18639	0.0161943319838057	0.628846153846154	0.883074406042493	0.988589450380263
GO:0004679	AMP-activated protein kinase activity	4/480	248/18639	0.0161290322580645	0.626310483870968	0.884946832731048	0.988589450380263
GO:0005254	chloride channel activity	1/480	83/18639	0.0120481927710843	0.467846385542169	0.885856447307324	0.988589450380263
GO:0019903	protein phosphatase binding	2/480	144/18639	0.0138888888888889	0.539322916666667	0.888686745741534	0.988589450380263
GO:0019955	cytokine binding	2/480	144/18639	0.0138888888888889	0.539322916666667	0.888686745741534	0.988589450380263
GO:0050660	flavin adenine dinucleotide binding	1/480	86/18639	0.0116279069767442	0.451526162790698	0.894487618015554	0.991425244760232
GO:0004842	ubiquitin-protein transferase activity	8/480	449/18639	0.0178173719376392	0.691870824053452	0.895519868944138	0.991425244760232
GO:0141003	histone H2AX kinase activity	6/480	354/18639	0.0169491525423729	0.658156779661017	0.896504753506719	0.991425244760232
GO:0008081	phosphoric diester hydrolase activity	1/480	87/18639	0.0114942528735632	0.446336206896552	0.897217416072608	0.991425244760232
GO:0140996	histone H3 kinase activity	6/480	357/18639	0.0168067226890756	0.652626050420168	0.900810157970861	0.991750619791486
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	1/480	89/18639	0.0112359550561798	0.436306179775281	0.90246738369262	0.991750619791486
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	1/480	89/18639	0.0112359550561798	0.436306179775281	0.90246738369262	0.991750619791486
GO:0005516	calmodulin binding	3/480	207/18639	0.0144927536231884	0.562771739130435	0.904800024417018	0.991750619791486
GO:0140793	histone H2AXY142 phosphatase activity	1/480	90/18639	0.0111111111111111	0.431458333333333	0.904991138723754	0.991750619791486
GO:0042562	hormone binding	1/480	94/18639	0.0106382978723404	0.413098404255319	0.914451017740637	0.999993114425289
GO:0016407	acetyltransferase activity	1/480	96/18639	0.0104166666666667	0.4044921875	0.91882234875651	0.999993114425289
GO:0003689	DNA clamp loader activity	2/480	160/18639	0.0125	0.485390625	0.920430388654364	0.999993114425289
GO:0004725	protein tyrosine phosphatase activity	1/480	98/18639	0.0102040816326531	0.396237244897959	0.922970757634295	0.999993114425289
GO:0008170	N-methyltransferase activity	1/480	98/18639	0.0102040816326531	0.396237244897959	0.922970757634295	0.999993114425289
GO:0016791	phosphatase activity	4/480	273/18639	0.0146520146520147	0.568956043956044	0.923962360046899	0.999993114425289
GO:0005126	cytokine receptor binding	4/480	275/18639	0.0145454545454545	0.564818181818182	0.926501767603723	0.999993114425289
GO:0015103	inorganic anion transmembrane transporter activity	2/480	165/18639	0.0121212121212121	0.470681818181818	0.92846035733639	0.999993114425289
GO:0030246	carbohydrate binding	4/480	280/18639	0.0142857142857143	0.554732142857143	0.93251979611569	0.999993114425289
GO:0000149	SNARE binding	1/480	106/18639	0.00943396226415094	0.366332547169811	0.937553615206477	0.999993114425289
GO:0008013	beta-catenin binding	1/480	106/18639	0.00943396226415094	0.366332547169811	0.937553615206477	0.999993114425289
GO:0005244	voltage-gated monoatomic ion channel activity	2/480	173/18639	0.0115606936416185	0.448916184971098	0.939737094501116	0.999993114425289
GO:0015291	secondary active transmembrane transporter activity	4/480	287/18639	0.0139372822299652	0.541202090592334	0.940197686734325	0.999993114425289
GO:0022832	voltage-gated channel activity	2/480	175/18639	0.0114285714285714	0.443785714285714	0.942280828214843	0.999993114425289
GO:0004620	phospholipase activity	1/480	109/18639	0.00917431192660551	0.35625	0.942281318630137	0.999993114425289
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	2/480	181/18639	0.0110497237569061	0.429074585635359	0.949314001345636	0.999993114425289
GO:0061630	ubiquitin protein ligase activity	5/480	353/18639	0.0141643059490085	0.550017705382436	0.951629679977427	0.999993114425289
GO:0015294	solute:monoatomic cation symporter activity	1/480	116/18639	0.00862068965517241	0.334752155172414	0.95196964268628	0.999993114425289
GO:1901981	phosphatidylinositol phosphate binding	2/480	185/18639	0.0108108108108108	0.419797297297297	0.953540805315501	0.999993114425289
GO:0008234	cysteine-type peptidase activity	2/480	187/18639	0.0106951871657754	0.415307486631016	0.955525918306034	0.999993114425289
GO:0015108	chloride transmembrane transporter activity	1/480	121/18639	0.00826446280991736	0.320919421487603	0.957879192251389	0.999993114425289
GO:0042578	phosphoric ester hydrolase activity	5/480	363/18639	0.0137741046831956	0.534865702479339	0.959017145568059	0.999993114425289
GO:0061659	ubiquitin-like protein ligase activity	5/480	372/18639	0.0134408602150538	0.521925403225806	0.964768753668926	0.999993114425289
GO:0035591	signaling adaptor activity	1/480	129/18639	0.00775193798449612	0.301017441860465	0.965862348970489	0.999993114425289
GO:0016298	lipase activity	1/480	130/18639	0.00769230769230769	0.298701923076923	0.966747604102534	0.999993114425289
GO:0005262	calcium channel activity	1/480	131/18639	0.00763358778625954	0.296421755725191	0.967609949449705	0.999993114425289
GO:0030371	translation repressor activity	4/480	329/18639	0.0121580547112462	0.472112462006079	0.971790383337167	0.999993114425289
GO:0140098	catalytic activity, acting on RNA	5/480	387/18639	0.0129198966408269	0.501695736434108	0.972730802407232	0.999993114425289
GO:0070851	growth factor receptor binding	1/480	139/18639	0.00719424460431655	0.279361510791367	0.973751856234541	0.999993114425289
GO:0140101	catalytic activity, acting on a tRNA	1/480	139/18639	0.00719424460431655	0.279361510791367	0.973751856234541	0.999993114425289
GO:0015293	symporter activity	1/480	146/18639	0.00684931506849315	0.265967465753425	0.978164312563951	0.999993114425289
GO:0035091	phosphatidylinositol binding	3/480	284/18639	0.0105633802816901	0.41018926056338	0.978543683541535	0.999993114425289
GO:0015085	calcium ion transmembrane transporter activity	1/480	147/18639	0.00680272108843537	0.264158163265306	0.978731074580352	0.999993114425289
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	2/480	229/18639	0.00873362445414847	0.339137554585153	0.982535311107309	0.999993114425289
GO:0005085	guanyl-nucleotide exchange factor activity	2/480	230/18639	0.00869565217391304	0.337663043478261	0.982925985700961	0.999993114425289
GO:0140658	ATP-dependent chromatin remodeler activity	1/480	158/18639	0.00632911392405063	0.245767405063291	0.984075357132697	0.999993114425289
GO:0140713	histone chaperone activity	1/480	164/18639	0.00609756097560976	0.236775914634146	0.986401616356704	0.999993114425289
GO:0005201	extracellular matrix structural constituent	1/480	168/18639	0.00595238095238095	0.231138392857143	0.987760796874474	0.999993114425289
GO:0042277	peptide binding	2/480	249/18639	0.00803212851405622	0.311897590361446	0.988922645534521	0.999993114425289
GO:0003823	antigen binding	1/480	174/18639	0.00574712643678161	0.223168103448276	0.98954959545999	0.999993114425289
GO:0004252	serine-type endopeptidase activity	1/480	176/18639	0.00568181818181818	0.220632102272727	0.990085867129159	0.999993114425289
GO:0005319	lipid transporter activity	1/480	178/18639	0.00561797752808989	0.21815308988764	0.990594673933682	0.999993114425289
GO:0005216	monoatomic ion channel activity	5/480	448/18639	0.0111607142857143	0.433384486607143	0.99082790211018	0.999993114425289
GO:0016757	glycosyltransferase activity	2/480	267/18639	0.00749063670411985	0.290870786516854	0.992681012247509	0.999993114425289
GO:0140597	protein carrier chaperone	1/480	188/18639	0.00531914893617021	0.20654920212766	0.992773437316279	0.999993114425289
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	2/480	268/18639	0.00746268656716418	0.289785447761194	0.992848457220523	0.999993114425289
GO:0008514	organic anion transmembrane transporter activity	2/480	269/18639	0.00743494423791822	0.288708178438662	0.993012156214799	0.999993114425289
GO:0005096	GTPase activator activity	2/480	271/18639	0.00738007380073801	0.286577490774908	0.993328639941313	0.999993114425289
GO:0008236	serine-type peptidase activity	1/480	194/18639	0.00515463917525773	0.200161082474227	0.993830693403384	0.999993114425289
GO:0016758	hexosyltransferase activity	1/480	197/18639	0.0050761421319797	0.197112944162437	0.994299930481231	0.999993114425289
GO:0001217	DNA-binding transcription repressor activity	2/480	278/18639	0.00719424460431655	0.279361510791367	0.994329755714691	0.999993114425289
GO:0017171	serine hydrolase activity	1/480	198/18639	0.00505050505050505	0.196117424242424	0.994448289301804	0.999993114425289
GO:0022836	gated channel activity	2/480	318/18639	0.00628930817610063	0.244221698113208	0.997783469521272	0.999993114425289
GO:0005261	monoatomic cation channel activity	2/480	341/18639	0.00586510263929619	0.22774926686217	0.998717437440235	0.999993114425289
GO:0030695	GTPase regulator activity	4/480	489/18639	0.0081799591002045	0.317638036809816	0.998817624727518	0.999993114425289
GO:0060589	nucleoside-triphosphatase regulator activity	4/480	490/18639	0.00816326530612245	0.316989795918367	0.998842193248705	0.999993114425289
GO:0004175	endopeptidase activity	2/480	405/18639	0.00493827160493827	0.191759259259259	0.999726303390265	0.999993114425289
GO:0046873	metal ion transmembrane transporter activity	1/480	450/18639	0.00222222222222222	0.0862916666666667	0.999993114425289	0.999993114425289