category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Genetic Information Processing	Translation	hsa03010	Ribosome	49/91	222/9376	22.7415107415107	RPL10A/RPLP0/RPS14/RPL27A/UBA52/RPS10/RPL5/RPS3A/RPS8/RPSA/RPS5/RPL7A/RPS12/RPL19/RPS19/RPS16/RPS3/RPS20/RPL29/RPL15/RPL3/RPS23/RPS4Y1/RPS4X/RPS6/RPS11/RPL13/RPS25/RPS18/RPS2/RPL23A/RPL7/RPL8/RPL23/RPL24/RPL18/RPS27A/RPL6/RPS13/RPL13A/RPL9/RPLP1/RPL32/RPL18A/RPLP2/RPL11/RPL10/RPS17/RPL14	32.4545903632584
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	49/91	238/9376	21.2126696832579	RPL10A/RPLP0/RPS14/RPL27A/UBA52/RPS10/RPL5/RPS3A/RPS8/RPSA/RPS5/RPL7A/RPS12/RPL19/RPS19/RPS16/RPS3/RPS20/RPL29/RPL15/RPL3/RPS23/RPS4Y1/RPS4X/RPS6/RPS11/RPL13/RPS25/RPS18/RPS2/RPL23A/RPL7/RPL8/RPL23/RPL24/RPL18/RPS27A/RPL6/RPS13/RPL13A/RPL9/RPLP1/RPL32/RPL18A/RPLP2/RPL11/RPL10/RPS17/RPL14	31.2681337346082
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	16/91	268/9376	6.15122191241594	SLC25A6/UBA52/MT-ATP6/MT-CO1/RPS27A/NDUFB10/SOD1/UBB/TUBA1B/MT-CYB/MT-CO3/SLC25A5/PSMB3/NDUFA11/TUBB4B/MT-ND1	8.46996324759465
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	14/91	308/9376	4.68331668331668	SLC25A6/MT-ATP6/MT-CO1/GPX3/NDUFB10/SOD1/TUBA1B/MT-CYB/MT-CO3/SLC25A5/PSMB3/NDUFA11/TUBB4B/MT-ND1	6.50689865988282
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	13/91	275/9376	4.87064935064935	SLC25A6/MT-ATP6/MT-CO1/NDUFB10/SOD1/TUBA1B/MT-CYB/MT-CO3/SLC25A5/PSMB3/NDUFA11/TUBB4B/MT-ND1	6.44942504265504
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	17/91	480/9376	3.64908424908425	SLC25A6/UBA52/MT-ATP6/MT-CO1/GPX3/RPS27A/NDUFB10/SOD1/UBB/TUBA1B/MT-CYB/MT-CO3/SLC25A5/PSMB3/NDUFA11/TUBB4B/MT-ND1	5.89840219237563
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	10/91	205/9376	5.02599839185205	GAPDH/SLC25A6/MT-ATP6/MT-CO1/NDUFB10/MT-CYB/MT-CO3/SLC25A5/NDUFA11/MT-ND1	5.76975751121511
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	10/91	227/9376	4.5388972261219	SLC25A6/MT-ATP6/MT-CO1/NDUFB10/SOD1/MT-CYB/MT-CO3/SLC25A5/NDUFA11/MT-ND1	5.34329861140339
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	13/91	388/9376	3.45213549337261	GAPDH/SLC25A6/MT-ATP6/MT-CO1/NDUFB10/TUBA1B/MT-CYB/MT-CO3/SLC25A5/PSMB3/NDUFA11/TUBB4B/MT-ND1	4.88364598901249
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	12/91	368/9376	3.35977066411849	MT-ATP6/MT-CO1/GPX3/NDUFB10/SOD1/TUBA1B/MT-CYB/MT-CO3/PSMB3/NDUFA11/TUBB4B/MT-ND1	4.5718807996435
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	7/91	138/9376	5.2263099219621	MT-ATP6/MT-CO1/NDUFB10/MT-CYB/MT-CO3/NDUFA11/MT-ND1	4.95139171854358
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	5/91	67/9376	7.68902739051993	GAPDH/TPI1/LDHA/ALDOA/PGAM1	5.4395658783502
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	8/91	235/9376	3.50750526069675	RPS6/MT-ATP6/MT-CO1/NDUFB10/MT-CYB/MT-CO3/NDUFA11/MT-ND1	3.85384558824307
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	8/91	248/9376	3.32364409783765	GAPDH/ANXA2/RPS3/TUBA1B/S100A10/ARPC5/TUBB4B/DYNLL1	3.67132654915428
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	5/91	116/9376	4.4410761652141	GAPDH/TPI1/GCSH/ALDOA/PGAM1	3.69175751025337
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	4/91	75/9376	5.49509157509157	GAPDH/TPI1/ALDOA/PGAM1	3.86918712130293
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	5/91	157/9376	3.28130468257857	MT-CO1/NDUFB10/MT-CYB/MT-CO3/NDUFA11	2.85368866987334
NA	NA	hsa04382	Cornified envelope formation	6/91	217/9376	2.84883779814655	KRT19/KRT8/KRT18/KRT23/S100A10/KRT7	2.72784713352729
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	3/91	59/9376	5.2389644254051	PRDX6/GPX3/GSTP1	3.23342737067855
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	4/91	110/9376	3.74665334665335	GAPDH/RPS6/LDHA/ALDOA	2.86859624654366
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	5/91	200/9376	2.57582417582418	GAPDH/RPS3/TUBA1B/ARPC5/TUBB4B	2.23003374423706
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	2/91	35/9376	5.88759811616954	TPI1/ALDOA	2.86779567342049
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	3/91	87/9376	3.55286093217128	MT-CO1/MT-CYB/MT-CO3	2.36819621315763
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	2/91	41/9376	5.02599839185205	GCSH/PGAM1	2.55754771337433
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/91	99/9376	3.12221112221112	KRT19/KRT18/KRT23	2.10144382743072
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	3/91	105/9376	2.94379905808477	UBA52/RPS27A/UBB	1.98288764448934
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	2/91	71/9376	2.9023370995202	LDHA/PGAM1	1.59284619928571
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/91	139/9376	2.22373310143094	KRT19/KRT18/KRT23	1.43894440973295
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	3/91	142/9376	2.17675282464015	UBA52/RPS27A/UBB	1.39878145835002
Organismal Systems	Digestive system	hsa04980	Cobalamin transport and metabolism	1/91	18/9376	5.72405372405372	PRDX1	1.98598031932169
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	3/91	144/9376	2.14652014652015	SLC25A6/SLC25A5/PSMB3	1.37255709465117
Metabolism	Metabolism of cofactors and vitamins	hsa00785	Lipoic acid metabolism	1/91	19/9376	5.42278773857721	GCSH	1.91038088057249
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	3/91	149/9376	2.07448926912014	NDUFB10/NDUFA11/MT-ND1	1.30882124761531
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	2/91	83/9376	2.48272209717993	PRDX1/SOD1	1.34318618981514
NA	NA	hsa04519	Cadherin signaling	6/91	404/9376	1.53019257969753	KRT19/KRT8/KRT18/KRT23/ARPC5/KRT7	1.07843773522888
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	2/91	89/9376	2.31534757377454	TUBA1B/TUBB4B	1.23427857070989
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	3/91	169/9376	1.82898758046687	UBA52/RPS27A/UBB	1.07658341527207
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	4/91	253/9376	1.62897971593624	UBA52/RPS27A/UBB/ARPC5	1.00402249566522
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/91	98/9376	2.10271361291769	ARPC5/CFL1	1.08633549520499
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/91	31/9376	3.32364409783765	ALDOA	1.28285090307965
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/91	31/9376	3.32364409783765	GCSH	1.28285090307965
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/91	32/9376	3.21978021978022	LDHA	1.24518514727976
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	2/91	107/9376	1.9258498510835	LDHA/PGAM1	0.953523474198128
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	2/91	108/9376	1.90801790801791	EEF1A1/RAN	0.939568956766849
Cellular Processes	Cell motility	hsa04814	Motor proteins	3/91	194/9376	1.59329330463351	TUBA1B/TUBB4B/DYNLL1	0.826641202966008
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	3/91	196/9376	1.57703520968827	UBA52/RPS27A/UBB	0.808210315594703
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/91	37/9376	2.78467478467479	COMT	1.07677544258122
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/91	39/9376	2.64187094956326	GCSH	1.01714536209945
NA	NA	hsa04517	IgSF CAM signaling	4/91	299/9376	1.37836745194605	TUBA1B/ARPC5/TUBB4B/DYNLL1	0.658254106424093
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/91	44/9376	2.34165834165834	DYNLL1	0.883072354005412
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	1/91	46/9376	2.23984710941233	PSMB3	0.834490905787401
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/91	47/9376	2.19219078793547	LDHA	0.811133847822409
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	3/91	224/9376	1.37990580847724	SLC25A6/SLC25A5/RAN	0.569714558289765
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/91	54/9376	1.90801790801791	LDHA	0.662448505633382
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/91	56/9376	1.83987441130298	EEF1A1	0.624044826805202
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/91	155/9376	1.32945763913506	TUBA1B/TUBB4B	0.409441444176826
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/91	61/9376	1.68906503332733	MT2A	0.534501687120191
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	2/91	157/9376	1.31252187303143	SLC25A6/SLC25A5	0.390934246954391
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/91	62/9376	1.66182204891882	SOD1	0.517588168250002
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/91	66/9376	1.56110556110556	COMT	0.452852824265025
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	2/91	166/9376	1.24136104858996	SLC25A6/SLC25A5	0.310603820394391
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	2/91	168/9376	1.22658294086866	SLC25A6/SLC25A5	0.293369239596847
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	2/91	170/9376	1.21215255332902	TUBA1B/ARPC5	0.27634564114003
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/91	70/9376	1.47189952904239	GSTP1	0.392312747650407
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	2/91	173/9376	1.19113256685511	SLC25A6/SLC25A5	0.251193509230924
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/91	73/9376	1.41141050730092	GSTP1	0.349333857161271
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/91	73/9376	1.41141050730092	RAN	0.349333857161271
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/91	75/9376	1.37377289377289	GSTP1	0.321728098909474
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/91	75/9376	1.37377289377289	GPX3	0.321728098909474
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/91	76/9376	1.3556969346443	DBI	0.308220006088872
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/91	78/9376	1.32093547478163	TPI1	0.281764085278784
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/91	78/9376	1.32093547478163	ARPC5	0.281764085278784
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/91	78/9376	1.32093547478163	CFL1	0.281764085278784
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/91	78/9376	1.32093547478163	EEF1A1	0.281764085278784
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/91	79/9376	1.3042147725692	GSTP1	0.268805289180164
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/91	80/9376	1.28791208791209	RPS6	0.256019010837866
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/91	82/9376	1.25649959796301	GSTP1	0.230944519836606
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/91	195/9376	1.0567483798253	SLC25A6/SLC25A5	0.0792758959861789
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/91	93/9376	1.10788136594588	CKS1B	0.103504472420903
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/91	100/9376	1.03032967032967	CD24	0.0301858006839421
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	1/91	103/9376	1.00032006828123	PRDX1	0.000323345261176289
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/91	106/9376	0.972009122952519	GSTP1	-0.0286909515746787
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	2/91	232/9376	0.888215233042819	ARPC5/CFL1	-0.170676563457483
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/91	116/9376	0.888215233042819	CD99	-0.119928253003496
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/91	254/9376	0.811283204983992	SLC25A6/SLC25A5	-0.301854571137414
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/91	133/9376	0.774683962653887	COMT	-0.259075788698471
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/91	137/9376	0.75206545279538	TUBA1B	-0.289401132260879
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/91	138/9376	0.746615703137442	RPS6	-0.29685587007585
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/91	138/9376	0.746615703137442	ARPC5	-0.29685587007585
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/91	140/9376	0.735949764521193	RPS6	-0.311619047071049
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/91	142/9376	0.72558427488005	GSTP1	-0.326192230126869
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/91	157/9376	0.656260936515714	CD24	-0.429983894018592
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/91	158/9376	0.652107386284601	RPS6	-0.436586980091273
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	1/91	160/9376	0.643956043956044	CD99	-0.44968433246425
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/91	170/9376	0.606076276664512	GSTP1	-0.513117104542153
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	1/91	183/9376	0.563021677775776	RAN	-0.590979189387673
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/91	184/9376	0.559961777353082	CFL1	-0.596773714359609
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	1/91	204/9376	0.505063563887093	RPS6	-0.707534901574204
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/91	214/9376	0.481462462770874	CFL1	-0.759639123442917
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/91	250/9376	0.412131868131868	ARPC5	-0.932663692053652
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	1/91	362/9376	0.284621455892174	RPS6	-1.37419004861247