ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0000287 magnesium ion binding 10/170 230/18639 0.0434782608695652 4.76700767263427 5.110499007586e-05 0.0239682403455783 GO:0004860 protein kinase inhibitor activity 5/170 84/18639 0.0595238095238095 6.52626050420168 0.00102754079651978 0.151946353355886 GO:0019207 kinase regulator activity 9/170 287/18639 0.0313588850174216 3.43822504611601 0.00130745715852367 0.151946353355886 GO:0019210 kinase inhibitor activity 5/170 90/18639 0.0555555555555556 6.09117647058823 0.0014001457528566 0.151946353355886 GO:0051219 phosphoprotein binding 5/170 93/18639 0.0537634408602151 5.89468690702087 0.00161989715731222 0.151946353355886 GO:0070888 E-box binding 4/170 59/18639 0.0677966101694915 7.4333000997009 0.00205746343560974 0.160825058550161 GO:0019887 protein kinase regulator activity 8/170 255/18639 0.0313725490196078 3.439723183391 0.00240400240109783 0.161068160873554 GO:0005381 iron ion transmembrane transporter activity 2/170 10/18639 0.2 21.9282352941176 0.00354679984172391 0.207931140721065 GO:0042887 amide transmembrane transporter activity 3/170 38/18639 0.0789473684210526 8.65588235294118 0.00497517275732974 0.259261780354183 GO:0035673 oligopeptide transmembrane transporter activity 2/170 13/18639 0.153846153846154 16.8678733031674 0.00603832430395826 0.283197409855642 GO:0061665 SUMO ligase activity 2/170 14/18639 0.142857142857143 15.663025210084 0.00700271181992213 0.298570167594862 GO:0046915 transition metal ion transmembrane transporter activity 3/170 45/18639 0.0666666666666667 7.30941176470588 0.00798883568340704 0.312230327959825 GO:0140297 DNA-binding transcription factor binding 10/170 488/18639 0.0204918032786885 2.24674541947927 0.0142490115198198 0.469283325946111 GO:0004857 enzyme inhibitor activity 9/170 416/18639 0.0216346153846154 2.37204468325792 0.0142902201569728 0.469283325946111 GO:0015295 solute:proton symporter activity 2/170 24/18639 0.0833333333333333 9.13676470588235 0.02001104101589 0.469283325946111 GO:0070300 phosphatidic acid binding 2/170 24/18639 0.0833333333333333 9.13676470588235 0.02001104101589 0.469283325946111 GO:0004252 serine-type endopeptidase activity 5/170 176/18639 0.0284090909090909 3.11480614973262 0.022744853089781 0.469283325946111 GO:0005548 phospholipid transporter activity 3/170 68/18639 0.0441176470588235 4.8371107266436 0.024246732151998 0.469283325946111 GO:0030145 manganese ion binding 3/170 68/18639 0.0441176470588235 4.8371107266436 0.024246732151998 0.469283325946111 GO:0005385 zinc ion transmembrane transporter activity 2/170 27/18639 0.0740740740740741 8.12156862745098 0.0250003484083355 0.469283325946111 GO:0019789 SUMO transferase activity 2/170 28/18639 0.0714285714285714 7.83151260504202 0.026764599111508 0.469283325946111 GO:0044389 ubiquitin-like protein ligase binding 7/170 322/18639 0.0217391304347826 2.38350383631714 0.0285258166955699 0.469283325946111 GO:0031072 heat shock protein binding 4/170 131/18639 0.0305343511450382 3.34782218230804 0.0320668563305821 0.469283325946111 GO:0008236 serine-type peptidase activity 5/170 194/18639 0.0257731958762887 2.8258035172832 0.0327236103227228 0.469283325946111 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 9/170 484/18639 0.0185950413223141 2.03878220709772 0.0337110433746908 0.469283325946111 GO:0045296 cadherin binding 7/170 334/18639 0.0209580838323353 2.29786896794646 0.0337972751368005 0.469283325946111 GO:0017171 serine hydrolase activity 5/170 198/18639 0.0252525252525253 2.76871657754011 0.0352592691792719 0.469283325946111 GO:0071889 14-3-3 protein binding 2/170 33/18639 0.0606060606060606 6.64491978609626 0.0362979501853582 0.469283325946111 GO:0140416 transcription regulator inhibitor activity 2/170 33/18639 0.0606060606060606 6.64491978609626 0.0362979501853582 0.469283325946111 GO:0001216 DNA-binding transcription activator activity 9/170 491/18639 0.0183299389002037 2.00971606565233 0.0364213359256549 0.469283325946111 GO:0003712 transcription coregulator activity 9/170 495/18639 0.0181818181818182 1.99347593582888 0.0380356166658268 0.469283325946111 GO:0019825 oxygen binding 2/170 34/18639 0.0588235294117647 6.44948096885813 0.0383400568777875 0.469283325946111 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 7/170 349/18639 0.0200573065902579 2.19910669138716 0.0412525450295318 0.469283325946111 GO:0015293 symporter activity 4/170 146/18639 0.0273972602739726 3.00386784850927 0.0448429049341496 0.469283325946111 GO:0015291 secondary active transmembrane transporter activity 6/170 287/18639 0.0209059233449477 2.29215003074401 0.0481578059232755 0.469283325946111 GO:0032451 demethylase activity 2/170 40/18639 0.05 5.48205882352941 0.0514607440768506 0.469283325946111 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/170 40/18639 0.05 5.48205882352941 0.0514607440768506 0.469283325946111 GO:0140662 ATP-dependent protein folding chaperone 2/170 40/18639 0.05 5.48205882352941 0.0514607440768506 0.469283325946111 GO:0140828 metal cation:monoatomic cation antiporter activity 2/170 41/18639 0.0487804878048781 5.34835007173601 0.0537837166464252 0.469283325946111 GO:0031625 ubiquitin protein ligase binding 6/170 302/18639 0.0198675496688742 2.17830151928321 0.0588066954223101 0.469283325946111 GO:0005085 guanyl-nucleotide exchange factor activity 5/170 230/18639 0.0217391304347826 2.38350383631714 0.0598729154255802 0.469283325946111 GO:0043014 alpha-tubulin binding 2/170 44/18639 0.0454545454545455 4.98368983957219 0.060968635945544 0.469283325946111 GO:0140303 intramembrane lipid transporter activity 2/170 45/18639 0.0444444444444444 4.87294117647059 0.0634328127019224 0.469283325946111 GO:0030291 protein serine/threonine kinase inhibitor activity 2/170 46/18639 0.0434782608695652 4.76700767263427 0.0659302232071274 0.469283325946111 GO:0043495 protein-membrane adaptor activity 2/170 47/18639 0.0425531914893617 4.66558197747184 0.0684600645138156 0.469283325946111 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/170 48/18639 0.0416666666666667 4.56838235294118 0.0710215454020634 0.469283325946111 GO:0008013 beta-catenin binding 3/170 106/18639 0.0283018867924528 3.10305216426193 0.0729244770212 0.469283325946111 GO:0016763 pentosyltransferase activity 2/170 49/18639 0.0408163265306122 4.47515006002401 0.0736138862343364 0.469283325946111 GO:0060590 ATPase regulator activity 2/170 49/18639 0.0408163265306122 4.47515006002401 0.0736138862343364 0.469283325946111 GO:0019888 protein phosphatase regulator activity 3/170 107/18639 0.0280373831775701 3.07405167674546 0.0745470715106704 0.469283325946111 GO:0035402 histone H3T11 kinase activity 5/170 247/18639 0.0202429149797571 2.21945701357466 0.076109115706489 0.469283325946111 GO:0016597 amino acid binding 2/170 51/18639 0.0392156862745098 4.29965397923875 0.0788880862340871 0.469283325946111 GO:0005246 calcium channel regulator activity 2/170 53/18639 0.0377358490566038 4.13740288568258 0.084276653652504 0.469283325946111 GO:0016251 RNA polymerase II general transcription initiation factor activity 2/170 53/18639 0.0377358490566038 4.13740288568258 0.084276653652504 0.469283325946111 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/170 53/18639 0.0377358490566038 4.13740288568258 0.084276653652504 0.469283325946111 GO:0004955 prostaglandin receptor activity 1/170 10/18639 0.1 10.9641176470588 0.0875731113630073 0.469283325946111 GO:0005131 growth hormone receptor binding 1/170 10/18639 0.1 10.9641176470588 0.0875731113630073 0.469283325946111 GO:0008140 cAMP response element binding protein binding 1/170 10/18639 0.1 10.9641176470588 0.0875731113630073 0.469283325946111 GO:0015279 store-operated calcium channel activity 1/170 10/18639 0.1 10.9641176470588 0.0875731113630073 0.469283325946111 GO:0031720 haptoglobin binding 1/170 10/18639 0.1 10.9641176470588 0.0875731113630073 0.469283325946111 GO:0050815 phosphoserine residue binding 1/170 10/18639 0.1 10.9641176470588 0.0875731113630073 0.469283325946111 GO:0099122 RNA polymerase II C-terminal domain binding 1/170 10/18639 0.1 10.9641176470588 0.0875731113630073 0.469283325946111 GO:0001221 transcription coregulator binding 3/170 115/18639 0.0260869565217391 2.86020460358056 0.0880925522904178 0.469283325946111 GO:0015294 solute:monoatomic cation symporter activity 3/170 116/18639 0.0258620689655172 2.8355476673428 0.0898542347100566 0.469283325946111 GO:0019208 phosphatase regulator activity 3/170 117/18639 0.0256410256410256 2.81131221719457 0.0916306621811699 0.469283325946111 GO:0030170 pyridoxal phosphate binding 2/170 56/18639 0.0357142857142857 3.91575630252101 0.0925612277441868 0.469283325946111 GO:0070279 vitamin B6 binding 2/170 57/18639 0.0350877192982456 3.84705882352941 0.095373724491006 0.469283325946111 GO:0004954 prostanoid receptor activity 1/170 11/18639 0.0909090909090909 9.96737967914438 0.0958995148773285 0.469283325946111 GO:0015173 aromatic amino acid transmembrane transporter activity 1/170 11/18639 0.0909090909090909 9.96737967914438 0.0958995148773285 0.469283325946111 GO:0140537 transcription regulator activator activity 1/170 11/18639 0.0909090909090909 9.96737967914438 0.0958995148773285 0.469283325946111 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/170 60/18639 0.0333333333333333 3.65470588235294 0.103954586781149 0.469283325946111 GO:0015166 polyol transmembrane transporter activity 1/170 12/18639 0.0833333333333333 9.13676470588235 0.104150378226633 0.469283325946111 GO:0015368 calcium:monoatomic cation antiporter activity 1/170 12/18639 0.0833333333333333 9.13676470588235 0.104150378226633 0.469283325946111 GO:0016840 carbon-nitrogen lyase activity 1/170 12/18639 0.0833333333333333 9.13676470588235 0.104150378226633 0.469283325946111 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/170 12/18639 0.0833333333333333 9.13676470588235 0.104150378226633 0.469283325946111 GO:0070679 inositol 1,4,5 trisphosphate binding 1/170 12/18639 0.0833333333333333 9.13676470588235 0.104150378226633 0.469283325946111 GO:0097677 STAT family protein binding 1/170 12/18639 0.0833333333333333 9.13676470588235 0.104150378226633 0.469283325946111 GO:0016836 hydro-lyase activity 2/170 61/18639 0.0327868852459016 3.59479267116683 0.106860460284221 0.469283325946111 GO:0042826 histone deacetylase binding 3/170 127/18639 0.0236220472440945 2.58994905048634 0.110173342314361 0.469283325946111 GO:0003779 actin binding 7/170 443/18639 0.0158013544018059 1.7324790864427 0.11145392384147 0.469283325946111 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/170 13/18639 0.0769230769230769 8.43393665158371 0.11232638272019 0.469283325946111 GO:0005172 vascular endothelial growth factor receptor binding 1/170 13/18639 0.0769230769230769 8.43393665158371 0.11232638272019 0.469283325946111 GO:0019855 calcium channel inhibitor activity 1/170 13/18639 0.0769230769230769 8.43393665158371 0.11232638272019 0.469283325946111 GO:0030955 potassium ion binding 1/170 13/18639 0.0769230769230769 8.43393665158371 0.11232638272019 0.469283325946111 GO:0071837 HMG box domain binding 1/170 13/18639 0.0769230769230769 8.43393665158371 0.11232638272019 0.469283325946111 GO:0140333 glycerophospholipid flippase activity 1/170 13/18639 0.0769230769230769 8.43393665158371 0.11232638272019 0.469283325946111 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/170 13/18639 0.0769230769230769 8.43393665158371 0.11232638272019 0.469283325946111 GO:0003714 transcription corepressor activity 4/170 204/18639 0.0196078431372549 2.14982698961938 0.116708563408358 0.469283325946111 GO:0005262 calcium channel activity 3/170 131/18639 0.0229007633587786 2.51086663673103 0.117965529859358 0.469283325946111 GO:0046873 metal ion transmembrane transporter activity 7/170 450/18639 0.0155555555555556 1.70552941176471 0.118311302954964 0.469283325946111 GO:0005161 platelet-derived growth factor receptor binding 1/170 14/18639 0.0714285714285714 7.83151260504202 0.120428203558672 0.469283325946111 GO:0005344 oxygen carrier activity 1/170 14/18639 0.0714285714285714 7.83151260504202 0.120428203558672 0.469283325946111 GO:0008174 mRNA methyltransferase activity 1/170 14/18639 0.0714285714285714 7.83151260504202 0.120428203558672 0.469283325946111 GO:0008191 metalloendopeptidase inhibitor activity 1/170 14/18639 0.0714285714285714 7.83151260504202 0.120428203558672 0.469283325946111 GO:0008195 phosphatidate phosphatase activity 1/170 14/18639 0.0714285714285714 7.83151260504202 0.120428203558672 0.469283325946111 GO:0008331 high voltage-gated calcium channel activity 1/170 14/18639 0.0714285714285714 7.83151260504202 0.120428203558672 0.469283325946111 GO:0032454 histone H3K9 demethylase activity 1/170 14/18639 0.0714285714285714 7.83151260504202 0.120428203558672 0.469283325946111 GO:0042813 Wnt receptor activity 1/170 14/18639 0.0714285714285714 7.83151260504202 0.120428203558672 0.469283325946111 GO:1901474 azole transmembrane transporter activity 1/170 14/18639 0.0714285714285714 7.83151260504202 0.120428203558672 0.469283325946111 GO:0050840 extracellular matrix binding 2/170 67/18639 0.0298507462686567 3.27287093942054 0.124729948058867 0.469283325946111 GO:0015297 antiporter activity 3/170 135/18639 0.0222222222222222 2.43647058823529 0.125957284479373 0.469283325946111 GO:0140223 general transcription initiation factor activity 2/170 68/18639 0.0294117647058824 3.22474048442907 0.127774893995439 0.469283325946111 GO:0000774 adenyl-nucleotide exchange factor activity 1/170 15/18639 0.0666666666666667 7.30941176470588 0.128456509888606 0.469283325946111 GO:0004089 carbonate dehydratase activity 1/170 15/18639 0.0666666666666667 7.30941176470588 0.128456509888606 0.469283325946111 GO:0004953 icosanoid receptor activity 1/170 15/18639 0.0666666666666667 7.30941176470588 0.128456509888606 0.469283325946111 GO:0015250 water channel activity 1/170 15/18639 0.0666666666666667 7.30941176470588 0.128456509888606 0.469283325946111 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/170 15/18639 0.0666666666666667 7.30941176470588 0.128456509888606 0.469283325946111 GO:0140776 protein-containing complex destabilizing activity 1/170 15/18639 0.0666666666666667 7.30941176470588 0.128456509888606 0.469283325946111 GO:0016922 nuclear receptor binding 3/170 137/18639 0.0218978102189781 2.40090167453843 0.130024877133263 0.469283325946111 GO:0070851 growth factor receptor binding 3/170 139/18639 0.0215827338129496 2.36635632670334 0.134138606711094 0.469283325946111 GO:0005159 insulin-like growth factor receptor binding 1/170 16/18639 0.0625 6.85257352941176 0.136411964856332 0.469283325946111 GO:0140327 flippase activity 1/170 16/18639 0.0625 6.85257352941176 0.136411964856332 0.469283325946111 GO:0140328 floppase activity 1/170 16/18639 0.0625 6.85257352941176 0.136411964856332 0.469283325946111 GO:0140098 catalytic activity, acting on RNA 6/170 387/18639 0.0155038759689922 1.69986320109439 0.143343048558914 0.469283325946111 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/170 17/18639 0.0588235294117647 6.44948096885813 0.144295225661489 0.469283325946111 GO:0004550 nucleoside diphosphate kinase activity 1/170 17/18639 0.0588235294117647 6.44948096885813 0.144295225661489 0.469283325946111 GO:0004659 prenyltransferase activity 1/170 17/18639 0.0588235294117647 6.44948096885813 0.144295225661489 0.469283325946111 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/170 17/18639 0.0588235294117647 6.44948096885813 0.144295225661489 0.469283325946111 GO:0008484 sulfuric ester hydrolase activity 1/170 17/18639 0.0588235294117647 6.44948096885813 0.144295225661489 0.469283325946111 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/170 17/18639 0.0588235294117647 6.44948096885813 0.144295225661489 0.469283325946111 GO:0016018 cyclosporin A binding 1/170 17/18639 0.0588235294117647 6.44948096885813 0.144295225661489 0.469283325946111 GO:0016805 dipeptidase activity 1/170 17/18639 0.0588235294117647 6.44948096885813 0.144295225661489 0.469283325946111 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/170 17/18639 0.0588235294117647 6.44948096885813 0.144295225661489 0.469283325946111 GO:0032183 SUMO binding 1/170 17/18639 0.0588235294117647 6.44948096885813 0.144295225661489 0.469283325946111 GO:0038191 neuropilin binding 1/170 17/18639 0.0588235294117647 6.44948096885813 0.144295225661489 0.469283325946111 GO:0051787 misfolded protein binding 1/170 17/18639 0.0588235294117647 6.44948096885813 0.144295225661489 0.469283325946111 GO:0019003 GDP binding 2/170 75/18639 0.0266666666666667 2.92376470588235 0.149548087538034 0.469283325946111 GO:0044183 protein folding chaperone 2/170 75/18639 0.0266666666666667 2.92376470588235 0.149548087538034 0.469283325946111 GO:0015085 calcium ion transmembrane transporter activity 3/170 147/18639 0.0204081632653061 2.237575030012 0.151029721511045 0.469283325946111 GO:0005372 water transmembrane transporter activity 1/170 18/18639 0.0555555555555556 6.09117647058823 0.15210694361002 0.469283325946111 GO:0017128 phospholipid scramblase activity 1/170 18/18639 0.0555555555555556 6.09117647058823 0.15210694361002 0.469283325946111 GO:0032393 MHC class I receptor activity 1/170 18/18639 0.0555555555555556 6.09117647058823 0.15210694361002 0.469283325946111 GO:0035615 clathrin adaptor activity 1/170 18/18639 0.0555555555555556 6.09117647058823 0.15210694361002 0.469283325946111 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/170 18/18639 0.0555555555555556 6.09117647058823 0.15210694361002 0.469283325946111 GO:0070628 proteasome binding 1/170 18/18639 0.0555555555555556 6.09117647058823 0.15210694361002 0.469283325946111 GO:0003724 RNA helicase activity 2/170 77/18639 0.025974025974026 2.84782276546982 0.155900221771533 0.469283325946111 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/170 19/18639 0.0526315789473684 5.77058823529412 0.159847764166719 0.469283325946111 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/170 19/18639 0.0526315789473684 5.77058823529412 0.159847764166719 0.469283325946111 GO:0022821 solute:potassium antiporter activity 1/170 19/18639 0.0526315789473684 5.77058823529412 0.159847764166719 0.469283325946111 GO:0031420 alkali metal ion binding 1/170 19/18639 0.0526315789473684 5.77058823529412 0.159847764166719 0.469283325946111 GO:0034987 immunoglobulin receptor binding 1/170 19/18639 0.0526315789473684 5.77058823529412 0.159847764166719 0.469283325946111 GO:0042577 lipid phosphatase activity 1/170 19/18639 0.0526315789473684 5.77058823529412 0.159847764166719 0.469283325946111 GO:0050145 nucleoside monophosphate kinase activity 1/170 19/18639 0.0526315789473684 5.77058823529412 0.159847764166719 0.469283325946111 GO:0008186 ATP-dependent activity, acting on RNA 2/170 79/18639 0.0253164556962025 2.77572598659717 0.162303134501268 0.469283325946111 GO:0016835 carbon-oxygen lyase activity 2/170 79/18639 0.0253164556962025 2.77572598659717 0.162303134501268 0.469283325946111 GO:0046332 SMAD binding 2/170 79/18639 0.0253164556962025 2.77572598659717 0.162303134501268 0.469283325946111 GO:0004175 endopeptidase activity 6/170 405/18639 0.0148148148148148 1.6243137254902 0.166104757164116 0.469283325946111 GO:0015095 magnesium ion transmembrane transporter activity 1/170 20/18639 0.05 5.48205882352941 0.167518327007302 0.469283325946111 GO:0016505 peptidase activator activity involved in apoptotic process 1/170 20/18639 0.05 5.48205882352941 0.167518327007302 0.469283325946111 GO:0001618 virus receptor activity 2/170 81/18639 0.0246913580246914 2.70718954248366 0.168752920445821 0.469283325946111 GO:0030971 receptor tyrosine kinase binding 2/170 81/18639 0.0246913580246914 2.70718954248366 0.168752920445821 0.469283325946111 GO:0140272 exogenous protein binding 2/170 82/18639 0.024390243902439 2.67417503586801 0.171994204340481 0.469283325946111 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/170 21/18639 0.0476190476190476 5.22100840336134 0.17511926607002 0.469283325946111 GO:0015174 basic amino acid transmembrane transporter activity 1/170 21/18639 0.0476190476190476 5.22100840336134 0.17511926607002 0.469283325946111 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/170 21/18639 0.0476190476190476 5.22100840336134 0.17511926607002 0.469283325946111 GO:0140312 cargo adaptor activity 1/170 21/18639 0.0476190476190476 5.22100840336134 0.17511926607002 0.469283325946111 GO:1904047 S-adenosyl-L-methionine binding 1/170 21/18639 0.0476190476190476 5.22100840336134 0.17511926607002 0.469283325946111 GO:0016887 ATP hydrolysis activity 6/170 417/18639 0.0143884892086331 1.5775708844689 0.182084120223648 0.469283325946111 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 4/170 243/18639 0.0164609053497942 1.80479302832244 0.182115733709843 0.469283325946111 GO:0008093 cytoskeletal anchor activity 1/170 22/18639 0.0454545454545455 4.98368983957219 0.182651209606819 0.469283325946111 GO:0016881 acid-amino acid ligase activity 1/170 22/18639 0.0454545454545455 4.98368983957219 0.182651209606819 0.469283325946111 GO:0016209 antioxidant activity 2/170 86/18639 0.0232558139534884 2.54979480164159 0.185057933446678 0.469283325946111 GO:0004676 3-phosphoinositide-dependent protein kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0004711 ribosomal protein S6 kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0035175 histone H3S10 kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0035979 histone H2AXS139 kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0044022 histone H3S28 kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0044023 histone H4S1 kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0044024 histone H2AS1 kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0044025 histone H2BS14 kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0072354 histone H3T3 kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0072371 histone H2AS121 kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0072518 Rho-dependent protein serine/threonine kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0140823 histone H2BS36 kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0140855 histone H3S57 kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0140995 histone H2A kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0140997 histone H4 kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0140998 histone H2B kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:1990244 histone H2AT120 kinase activity 4/170 245/18639 0.0163265306122449 1.7900600240096 0.185756083578814 0.469283325946111 GO:0004677 DNA-dependent protein kinase activity 4/170 246/18639 0.016260162601626 1.78278335724534 0.187585211210525 0.469283325946111 GO:0140857 histone H3T45 kinase activity 4/170 246/18639 0.016260162601626 1.78278335724534 0.187585211210525 0.469283325946111 GO:0008081 phosphoric diester hydrolase activity 2/170 87/18639 0.0229885057471264 2.52048681541582 0.188346299002218 0.469283325946111 GO:0035403 histone H3T6 kinase activity 4/170 247/18639 0.0161943319838057 1.77556561085973 0.189420208667381 0.469283325946111 GO:0042393 histone binding 4/170 247/18639 0.0161943319838057 1.77556561085973 0.189420208667381 0.469283325946111 GO:0000295 adenine nucleotide transmembrane transporter activity 1/170 23/18639 0.0434782608695652 4.76700767263427 0.190114780234032 0.469283325946111 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/170 23/18639 0.0434782608695652 4.76700767263427 0.190114780234032 0.469283325946111 GO:0005158 insulin receptor binding 1/170 23/18639 0.0434782608695652 4.76700767263427 0.190114780234032 0.469283325946111 GO:0042171 lysophosphatidic acid acyltransferase activity 1/170 23/18639 0.0434782608695652 4.76700767263427 0.190114780234032 0.469283325946111 GO:0071617 lysophospholipid acyltransferase activity 1/170 23/18639 0.0434782608695652 4.76700767263427 0.190114780234032 0.469283325946111 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/170 23/18639 0.0434782608695652 4.76700767263427 0.190114780234032 0.469283325946111 GO:0004679 AMP-activated protein kinase activity 4/170 248/18639 0.0161290322580645 1.76840607210626 0.19126100186712 0.469640889401462 GO:0050699 WW domain binding 1/170 24/18639 0.0416666666666667 4.56838235294118 0.197510594982647 0.469970189939489 GO:0060229 lipase activator activity 1/170 24/18639 0.0416666666666667 4.56838235294118 0.197510594982647 0.469970189939489 GO:0070840 dynein complex binding 1/170 24/18639 0.0416666666666667 4.56838235294118 0.197510594982647 0.469970189939489 GO:0005537 D-mannose binding 1/170 25/18639 0.04 4.38564705882353 0.204839265348103 0.469970189939489 GO:0008483 transaminase activity 1/170 25/18639 0.04 4.38564705882353 0.204839265348103 0.469970189939489 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/170 25/18639 0.04 4.38564705882353 0.204839265348103 0.469970189939489 GO:0003713 transcription coactivator activity 4/170 256/18639 0.015625 1.71314338235294 0.206187084861935 0.469970189939489 GO:0051213 dioxygenase activity 2/170 93/18639 0.021505376344086 2.35787476280835 0.208232452509835 0.469970189939489 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/170 26/18639 0.0384615384615385 4.21696832579186 0.212101397339658 0.469970189939489 GO:0004435 phosphatidylinositol phospholipase C activity 1/170 26/18639 0.0384615384615385 4.21696832579186 0.212101397339658 0.469970189939489 GO:0008157 protein phosphatase 1 binding 1/170 26/18639 0.0384615384615385 4.21696832579186 0.212101397339658 0.469970189939489 GO:0008198 ferrous iron binding 1/170 26/18639 0.0384615384615385 4.21696832579186 0.212101397339658 0.469970189939489 GO:0015216 purine nucleotide transmembrane transporter activity 1/170 26/18639 0.0384615384615385 4.21696832579186 0.212101397339658 0.469970189939489 GO:0043548 phosphatidylinositol 3-kinase binding 1/170 26/18639 0.0384615384615385 4.21696832579186 0.212101397339658 0.469970189939489 GO:0051139 metal cation:proton antiporter activity 1/170 26/18639 0.0384615384615385 4.21696832579186 0.212101397339658 0.469970189939489 GO:0052742 phosphatidylinositol kinase activity 1/170 26/18639 0.0384615384615385 4.21696832579186 0.212101397339658 0.469970189939489 GO:0070412 R-SMAD binding 1/170 26/18639 0.0384615384615385 4.21696832579186 0.212101397339658 0.469970189939489 GO:0120014 phospholipid transfer activity 1/170 26/18639 0.0384615384615385 4.21696832579186 0.212101397339658 0.469970189939489 GO:0003823 antigen binding 3/170 174/18639 0.0172413793103448 1.89036511156187 0.212280621650752 0.469970189939489 GO:0001671 ATPase activator activity 1/170 27/18639 0.037037037037037 4.06078431372549 0.219297591529325 0.469970189939489 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/170 27/18639 0.037037037037037 4.06078431372549 0.219297591529325 0.469970189939489 GO:0023026 MHC class II protein complex binding 1/170 27/18639 0.037037037037037 4.06078431372549 0.219297591529325 0.469970189939489 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/170 27/18639 0.037037037037037 4.06078431372549 0.219297591529325 0.469970189939489 GO:0005319 lipid transporter activity 3/170 178/18639 0.0168539325842697 1.84788499669531 0.221788706155423 0.469970189939489 GO:0141003 histone H2AX kinase activity 5/170 354/18639 0.0141242937853107 1.54860418743769 0.222524926997865 0.469970189939489 GO:0036408 histone H3K14 acetyltransferase activity 1/170 28/18639 0.0357142857142857 3.91575630252101 0.226428443100355 0.469970189939489 GO:0046966 nuclear thyroid hormone receptor binding 1/170 28/18639 0.0357142857142857 3.91575630252101 0.226428443100355 0.469970189939489 GO:0097718 disordered domain specific binding 1/170 28/18639 0.0357142857142857 3.91575630252101 0.226428443100355 0.469970189939489 GO:0141052 histone H3 demethylase activity 1/170 28/18639 0.0357142857142857 3.91575630252101 0.226428443100355 0.469970189939489 GO:0016757 glycosyltransferase activity 4/170 267/18639 0.0149812734082397 1.64256444150694 0.227238438339781 0.469970189939489 GO:0140996 histone H3 kinase activity 5/170 357/18639 0.0140056022408964 1.53559070687098 0.227494053917693 0.469970189939489 GO:0035173 histone kinase activity 5/170 360/18639 0.0138888888888889 1.52279411764706 0.232496108822849 0.469970189939489 GO:0004629 phospholipase C activity 1/170 29/18639 0.0344827586206897 3.78073022312373 0.233494541895312 0.469970189939489 GO:0010484 histone H3 acetyltransferase activity 1/170 29/18639 0.0344827586206897 3.78073022312373 0.233494541895312 0.469970189939489 GO:0016417 S-acyltransferase activity 1/170 29/18639 0.0344827586206897 3.78073022312373 0.233494541895312 0.469970189939489 GO:0035250 UDP-galactosyltransferase activity 1/170 29/18639 0.0344827586206897 3.78073022312373 0.233494541895312 0.469970189939489 GO:0043236 laminin binding 1/170 29/18639 0.0344827586206897 3.78073022312373 0.233494541895312 0.469970189939489 GO:0106222 lncRNA binding 1/170 29/18639 0.0344827586206897 3.78073022312373 0.233494541895312 0.469970189939489 GO:0042578 phosphoric ester hydrolase activity 5/170 363/18639 0.0137741046831956 1.5102090422946 0.23752986120275 0.469970189939489 GO:0008238 exopeptidase activity 2/170 102/18639 0.0196078431372549 2.14982698961938 0.238423183096301 0.469970189939489 GO:0015078 proton transmembrane transporter activity 3/170 185/18639 0.0162162162162162 1.77796502384738 0.238625863738631 0.469970189939489 GO:0022804 active transmembrane transporter activity 6/170 457/18639 0.0131291028446389 1.43949028188956 0.239330666326812 0.469970189939489 GO:0001968 fibronectin binding 1/170 30/18639 0.0333333333333333 3.65470588235294 0.240496472463705 0.469970189939489 GO:0015215 nucleotide transmembrane transporter activity 1/170 30/18639 0.0333333333333333 3.65470588235294 0.240496472463705 0.469970189939489 GO:0016769 transferase activity, transferring nitrogenous groups 1/170 30/18639 0.0333333333333333 3.65470588235294 0.240496472463705 0.469970189939489 GO:0032452 histone demethylase activity 1/170 30/18639 0.0333333333333333 3.65470588235294 0.240496472463705 0.469970189939489 GO:0043995 histone H4K5 acetyltransferase activity 1/170 30/18639 0.0333333333333333 3.65470588235294 0.240496472463705 0.469970189939489 GO:0043996 histone H4K8 acetyltransferase activity 1/170 30/18639 0.0333333333333333 3.65470588235294 0.240496472463705 0.469970189939489 GO:0043997 histone H4K12 acetyltransferase activity 1/170 30/18639 0.0333333333333333 3.65470588235294 0.240496472463705 0.469970189939489 GO:0005126 cytokine receptor binding 4/170 275/18639 0.0145454545454545 1.5947807486631 0.242881758638886 0.472662011625052 GO:0016411 acylglycerol O-acyltransferase activity 1/170 31/18639 0.032258064516129 3.53681214421252 0.247434814109208 0.475602163185322 GO:0017147 Wnt-protein binding 1/170 31/18639 0.032258064516129 3.53681214421252 0.247434814109208 0.475602163185322 GO:0140457 protein demethylase activity 1/170 31/18639 0.032258064516129 3.53681214421252 0.247434814109208 0.475602163185322 GO:0019902 phosphatase binding 3/170 190/18639 0.0157894736842105 1.73117647058824 0.250784442814924 0.479001831723687 GO:0008378 galactosyltransferase activity 1/170 32/18639 0.03125 3.42628676470588 0.254310140936456 0.479001831723687 GO:0015106 bicarbonate transmembrane transporter activity 1/170 32/18639 0.03125 3.42628676470588 0.254310140936456 0.479001831723687 GO:0022884 macromolecule transmembrane transporter activity 1/170 32/18639 0.03125 3.42628676470588 0.254310140936456 0.479001831723687 GO:0030515 snoRNA binding 1/170 32/18639 0.03125 3.42628676470588 0.254310140936456 0.479001831723687 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/170 33/18639 0.0303030303030303 3.32245989304813 0.261123021897428 0.485795074372816 GO:0030296 protein tyrosine kinase activator activity 1/170 33/18639 0.0303030303030303 3.32245989304813 0.261123021897428 0.485795074372816 GO:0140311 protein sequestering activity 1/170 33/18639 0.0303030303030303 3.32245989304813 0.261123021897428 0.485795074372816 GO:0004620 phospholipase activity 2/170 109/18639 0.018348623853211 2.01176470588235 0.26206002945911 0.485795074372816 GO:0005525 GTP binding 5/170 378/18639 0.0132275132275132 1.45028011204482 0.263130908044279 0.485859826270736 GO:0008376 acetylgalactosaminyltransferase activity 1/170 34/18639 0.0294117647058824 3.22474048442907 0.267874020837417 0.487097443169522 GO:0051427 hormone receptor binding 1/170 34/18639 0.0294117647058824 3.22474048442907 0.267874020837417 0.487097443169522 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/170 34/18639 0.0294117647058824 3.22474048442907 0.267874020837417 0.487097443169522 GO:0016758 hexosyltransferase activity 3/170 197/18639 0.0152284263959391 1.66966258584652 0.267955523108181 0.487097443169522 GO:0005154 epidermal growth factor receptor binding 1/170 35/18639 0.0285714285714286 3.13260504201681 0.274563696540596 0.490257734950025 GO:0010485 histone H4 acetyltransferase activity 1/170 35/18639 0.0285714285714286 3.13260504201681 0.274563696540596 0.490257734950025 GO:0043015 gamma-tubulin binding 1/170 35/18639 0.0285714285714286 3.13260504201681 0.274563696540596 0.490257734950025 GO:0140566 histone reader activity 1/170 35/18639 0.0285714285714286 3.13260504201681 0.274563696540596 0.490257734950025 GO:0016829 lyase activity 3/170 200/18639 0.015 1.64461764705882 0.275358052534685 0.490257734950025 GO:0000993 RNA polymerase II complex binding 1/170 36/18639 0.0277777777777778 3.04558823529412 0.281192602775174 0.490257734950025 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/170 36/18639 0.0277777777777778 3.04558823529412 0.281192602775174 0.490257734950025 GO:0055106 ubiquitin-protein transferase regulator activity 1/170 36/18639 0.0277777777777778 3.04558823529412 0.281192602775174 0.490257734950025 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/170 36/18639 0.0277777777777778 3.04558823529412 0.281192602775174 0.490257734950025 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/170 36/18639 0.0277777777777778 3.04558823529412 0.281192602775174 0.490257734950025 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/170 36/18639 0.0277777777777778 3.04558823529412 0.281192602775174 0.490257734950025 GO:0017124 SH3 domain binding 2/170 115/18639 0.0173913043478261 1.90680306905371 0.282339011465353 0.490433319915743 GO:0001664 G protein-coupled receptor binding 4/170 297/18639 0.0134680134680135 1.47664884135472 0.2870184971216 0.496176633200724 GO:0023023 MHC protein complex binding 1/170 37/18639 0.027027027027027 2.96327503974563 0.28776128833816 0.496176633200724 GO:1990782 protein tyrosine kinase binding 2/170 117/18639 0.0170940170940171 1.87420814479638 0.289091333463639 0.496644085693945 GO:0043531 ADP binding 1/170 38/18639 0.0263157894736842 2.88529411764706 0.294270297099719 0.503696238466307 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/170 39/18639 0.0256410256410256 2.81131221719457 0.300720168047143 0.506809197270336 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/170 39/18639 0.0256410256410256 2.81131221719457 0.300720168047143 0.506809197270336 GO:0019001 guanyl nucleotide binding 5/170 400/18639 0.0125 1.37051470588235 0.301735132953168 0.506809197270336 GO:0032561 guanyl ribonucleotide binding 5/170 400/18639 0.0125 1.37051470588235 0.301735132953168 0.506809197270336 GO:0003697 single-stranded DNA binding 2/170 121/18639 0.0165289256198347 1.81225085075352 0.302572655086768 0.506809197270336 GO:0051082 unfolded protein binding 2/170 121/18639 0.0165289256198347 1.81225085075352 0.302572655086768 0.506809197270336 GO:0004177 aminopeptidase activity 1/170 40/18639 0.025 2.74102941176471 0.307111435328433 0.510763344571046 GO:0015144 carbohydrate transmembrane transporter activity 1/170 40/18639 0.025 2.74102941176471 0.307111435328433 0.510763344571046 GO:0001727 lipid kinase activity 1/170 41/18639 0.024390243902439 2.67417503586801 0.313444628295483 0.515287997785202 GO:0140318 protein transporter activity 1/170 41/18639 0.024390243902439 2.67417503586801 0.313444628295483 0.515287997785202 GO:0004402 histone acetyltransferase activity 1/170 42/18639 0.0238095238095238 2.61050420168067 0.319720271546895 0.515287997785202 GO:0016859 cis-trans isomerase activity 1/170 42/18639 0.0238095238095238 2.61050420168067 0.319720271546895 0.515287997785202 GO:0019894 kinesin binding 1/170 42/18639 0.0238095238095238 2.61050420168067 0.319720271546895 0.515287997785202 GO:0042056 chemoattractant activity 1/170 42/18639 0.0238095238095238 2.61050420168067 0.319720271546895 0.515287997785202 GO:0043175 RNA polymerase core enzyme binding 1/170 42/18639 0.0238095238095238 2.61050420168067 0.319720271546895 0.515287997785202 GO:0048487 beta-tubulin binding 1/170 42/18639 0.0238095238095238 2.61050420168067 0.319720271546895 0.515287997785202 GO:0051879 Hsp90 protein binding 1/170 42/18639 0.0238095238095238 2.61050420168067 0.319720271546895 0.515287997785202 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/170 43/18639 0.0232558139534884 2.54979480164159 0.325938884970406 0.516614573812155 GO:0005245 voltage-gated calcium channel activity 1/170 43/18639 0.0232558139534884 2.54979480164159 0.325938884970406 0.516614573812155 GO:0008200 ion channel inhibitor activity 1/170 43/18639 0.0232558139534884 2.54979480164159 0.325938884970406 0.516614573812155 GO:0048156 tau protein binding 1/170 43/18639 0.0232558139534884 2.54979480164159 0.325938884970406 0.516614573812155 GO:0031490 chromatin DNA binding 2/170 128/18639 0.015625 1.71314338235294 0.326050989015774 0.516614573812155 GO:0001046 core promoter sequence-specific DNA binding 1/170 44/18639 0.0227272727272727 2.4918449197861 0.332100983784938 0.518430298439202 GO:0001223 transcription coactivator binding 1/170 44/18639 0.0227272727272727 2.4918449197861 0.332100983784938 0.518430298439202 GO:0016248 channel inhibitor activity 1/170 44/18639 0.0227272727272727 2.4918449197861 0.332100983784938 0.518430298439202 GO:0019205 nucleobase-containing compound kinase activity 1/170 44/18639 0.0227272727272727 2.4918449197861 0.332100983784938 0.518430298439202 GO:0016298 lipase activity 2/170 130/18639 0.0153846153846154 1.68678733031674 0.332723922878891 0.518430298439202 GO:0042605 peptide antigen binding 1/170 45/18639 0.0222222222222222 2.43647058823529 0.338207078582279 0.523495445066299 GO:0141110 transporter inhibitor activity 1/170 45/18639 0.0222222222222222 2.43647058823529 0.338207078582279 0.523495445066299 GO:0061134 peptidase regulator activity 3/170 226/18639 0.0132743362831858 1.45541384695471 0.34006000906508 0.524632053458956 GO:0004180 carboxypeptidase activity 1/170 46/18639 0.0217391304347826 2.38350383631714 0.344257675368393 0.529366720484513 GO:0051087 protein-folding chaperone binding 2/170 134/18639 0.0149253731343284 1.63643546971027 0.346012463653977 0.530326292332403 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/170 229/18639 0.0131004366812227 1.43634729000771 0.34753681946189 0.530927584129076 GO:0061733 protein-lysine-acetyltransferase activity 1/170 47/18639 0.0212765957446809 2.33279098873592 0.350253275604362 0.533340215124825 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/170 48/18639 0.0208333333333333 2.28419117647059 0.356194376246965 0.53888762083815 GO:0140693 molecular condensate scaffold activity 1/170 48/18639 0.0208333333333333 2.28419117647059 0.356194376246965 0.53888762083815 GO:0004674 protein serine/threonine kinase activity 5/170 433/18639 0.0115473441108545 1.26606439342481 0.361053779191722 0.544483030356648 GO:0030295 protein kinase activator activity 2/170 139/18639 0.0143884892086331 1.5775708844689 0.362500520255715 0.544912641025418 GO:0015605 organophosphate ester transmembrane transporter activity 1/170 50/18639 0.02 2.19282352941176 0.367915044298625 0.549529158522468 GO:0048020 CCR chemokine receptor binding 1/170 50/18639 0.02 2.19282352941176 0.367915044298625 0.549529158522468 GO:0003743 translation initiation factor activity 1/170 51/18639 0.0196078431372549 2.14982698961938 0.373695583459916 0.554630470388293 GO:0030544 Hsp70 protein binding 1/170 51/18639 0.0196078431372549 2.14982698961938 0.373695583459916 0.554630470388293 GO:0019903 protein phosphatase binding 2/170 144/18639 0.0138888888888889 1.52279411764706 0.378832632082823 0.55959010295769 GO:0030159 signaling receptor complex adaptor activity 1/170 52/18639 0.0192307692307692 2.10848416289593 0.379423566610971 0.55959010295769 GO:0008194 UDP-glycosyltransferase activity 2/170 145/18639 0.0137931034482759 1.51229208924949 0.382078626495506 0.561739422653267 GO:0034212 protein N-acetyltransferase activity 1/170 53/18639 0.0188679245283019 2.06870144284129 0.385099468783249 0.564411408935449 GO:0017069 snRNA binding 1/170 54/18639 0.0185185185185185 2.03039215686274 0.390723760739929 0.567500925174872 GO:0140463 chromatin-protein adaptor activity 1/170 54/18639 0.0185185185185185 2.03039215686274 0.390723760739929 0.567500925174872 GO:0019209 kinase activator activity 2/170 148/18639 0.0135135135135135 1.48163751987281 0.391773155540424 0.567500925174872 GO:0008374 O-acyltransferase activity 1/170 55/18639 0.0181818181818182 1.99347593582888 0.396296909014032 0.567500925174872 GO:0140313 molecular sequestering activity 1/170 55/18639 0.0181818181818182 1.99347593582888 0.396296909014032 0.567500925174872 GO:0140104 molecular carrier activity 3/170 249/18639 0.0120481927710843 1.32097802976612 0.397067170364645 0.567500925174872 GO:0019842 vitamin binding 2/170 150/18639 0.0133333333333333 1.46188235294118 0.398198606039183 0.567500925174872 GO:0000510 H3-H4 histone complex chaperone activity 2/170 151/18639 0.0132450331125828 1.45220101285547 0.40139966946063 0.567500925174872 GO:0140584 chromatin extrusion motor activity 2/170 151/18639 0.0132450331125828 1.45220101285547 0.40139966946063 0.567500925174872 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/170 151/18639 0.0132450331125828 1.45220101285547 0.40139966946063 0.567500925174872 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/170 151/18639 0.0132450331125828 1.45220101285547 0.40139966946063 0.567500925174872 GO:0015616 DNA translocase activity 2/170 152/18639 0.0131578947368421 1.44264705882353 0.404592791400634 0.567500925174872 GO:0140674 ATP-dependent histone chaperone activity 2/170 152/18639 0.0131578947368421 1.44264705882353 0.404592791400634 0.567500925174872 GO:0004601 peroxidase activity 1/170 57/18639 0.0175438596491228 1.92352941176471 0.407291619722197 0.567500925174872 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/170 57/18639 0.0175438596491228 1.92352941176471 0.407291619722197 0.567500925174872 GO:0016504 peptidase activator activity 1/170 57/18639 0.0175438596491228 1.92352941176471 0.407291619722197 0.567500925174872 GO:0061775 cohesin loader activity 2/170 153/18639 0.0130718954248366 1.43321799307958 0.407777850285569 0.567500925174872 GO:0004386 helicase activity 2/170 155/18639 0.0129032258064516 1.41472485768501 0.414123306797014 0.574156497353767 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/170 59/18639 0.0169491525423729 1.85832502492522 0.418087249996286 0.574156497353767 GO:0045309 protein phosphorylated amino acid binding 1/170 59/18639 0.0169491525423729 1.85832502492522 0.418087249996286 0.574156497353767 GO:0070063 RNA polymerase binding 1/170 59/18639 0.0169491525423729 1.85832502492522 0.418087249996286 0.574156497353767 GO:0106310 protein serine kinase activity 4/170 361/18639 0.0110803324099723 1.21486068111455 0.418925104549782 0.574156497353767 GO:0001098 basal transcription machinery binding 1/170 60/18639 0.0166666666666667 1.82735294117647 0.423411532423661 0.574156497353767 GO:0001099 basal RNA polymerase II transcription machinery binding 1/170 60/18639 0.0166666666666667 1.82735294117647 0.423411532423661 0.574156497353767 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/170 60/18639 0.0166666666666667 1.82735294117647 0.423411532423661 0.574156497353767 GO:0140658 ATP-dependent chromatin remodeler activity 2/170 158/18639 0.0126582278481013 1.38786299329859 0.423578140904911 0.574156497353767 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/170 61/18639 0.0163934426229508 1.79739633558341 0.428687383625985 0.57763312970944 GO:0003689 DNA clamp loader activity 2/170 160/18639 0.0125 1.37051470588235 0.429837872640926 0.57763312970944 GO:0099106 ion channel regulator activity 2/170 160/18639 0.0125 1.37051470588235 0.429837872640926 0.57763312970944 GO:0004866 endopeptidase inhibitor activity 2/170 161/18639 0.0124223602484472 1.36200219218122 0.432954383711067 0.579356976658338 GO:0015179 L-amino acid transmembrane transporter activity 1/170 62/18639 0.0161290322580645 1.76840607210626 0.4339152415646 0.579356976658338 GO:0046982 protein heterodimerization activity 4/170 369/18639 0.010840108401084 1.18852223816356 0.435240980203564 0.579356976658338 GO:0008083 growth factor activity 2/170 162/18639 0.0123456790123457 1.35359477124183 0.436061860896361 0.579356976658338 GO:0005507 copper ion binding 1/170 63/18639 0.0158730158730159 1.74033613445378 0.439095540263745 0.580100868686469 GO:1901682 sulfur compound transmembrane transporter activity 1/170 63/18639 0.0158730158730159 1.74033613445378 0.439095540263745 0.580100868686469 GO:0140713 histone chaperone activity 2/170 164/18639 0.0121951219512195 1.337087517934 0.442249336522144 0.582626232665408 GO:0008514 organic anion transmembrane transporter activity 3/170 269/18639 0.0111524163568773 1.22276404985786 0.445570110375549 0.585356811669839 GO:0120013 lipid transfer activity 1/170 65/18639 0.0153846153846154 1.68678733031674 0.449315176565861 0.58862798270779 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/170 167/18639 0.0119760479041916 1.31306798168369 0.451460502763998 0.58979101893124 GO:0008235 metalloexopeptidase activity 1/170 66/18639 0.0151515151515152 1.66122994652406 0.454355362846889 0.590487718704198 GO:0016247 channel regulator activity 2/170 168/18639 0.0119047619047619 1.30525210084034 0.45451186876805 0.590487718704198 GO:0030414 peptidase inhibitor activity 2/170 169/18639 0.0118343195266272 1.29752871562826 0.457553587030833 0.592797326843814 GO:0008173 RNA methyltransferase activity 1/170 67/18639 0.0149253731343284 1.63643546971027 0.459349687313374 0.59342601634 GO:0141108 transporter regulator activity 2/170 170/18639 0.0117647058823529 1.28989619377163 0.460585579119704 0.59342601634 GO:0030695 GTPase regulator activity 5/170 489/18639 0.0102249488752556 1.12107542403464 0.461834746192111 0.59342601634 GO:0060589 nucleoside-triphosphatase regulator activity 5/170 490/18639 0.0102040816326531 1.118787515006 0.463604794992129 0.594072811069149 GO:0001217 DNA-binding transcription repressor activity 3/170 278/18639 0.0107913669064748 1.18317816335167 0.466907692781808 0.59474575312071 GO:0015631 tubulin binding 4/170 385/18639 0.0103896103896104 1.13912910618793 0.467475036152841 0.59474575312071 GO:0002039 p53 binding 1/170 69/18639 0.0144927536231884 1.58900255754476 0.46920240651314 0.59474575312071 GO:0008080 N-acetyltransferase activity 1/170 69/18639 0.0144927536231884 1.58900255754476 0.46920240651314 0.59474575312071 GO:0097110 scaffold protein binding 1/170 70/18639 0.0142857142857143 1.5663025210084 0.474061619808389 0.599285443908718 GO:0005543 phospholipid binding 5/170 497/18639 0.0100603621730382 1.10302994437211 0.475947150694149 0.600051649665472 GO:0042379 chemokine receptor binding 1/170 72/18639 0.0138888888888889 1.52279411764706 0.483647772662891 0.608125483589533 GO:0043539 protein serine/threonine kinase activator activity 1/170 73/18639 0.0136986301369863 1.50193392425463 0.488375508896386 0.612026738016044 GO:0003684 damaged DNA binding 1/170 74/18639 0.0135135135135135 1.48163751987281 0.493060210150702 0.612026738016044 GO:0035064 methylated histone binding 1/170 74/18639 0.0135135135135135 1.48163751987281 0.493060210150702 0.612026738016044 GO:0048029 monosaccharide binding 1/170 74/18639 0.0135135135135135 1.48163751987281 0.493060210150702 0.612026738016044 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/170 181/18639 0.0110497237569061 1.21150471238219 0.493275281386066 0.612026738016044 GO:0061135 endopeptidase regulator activity 2/170 184/18639 0.0108695652173913 1.19175191815857 0.501973360613457 0.616700699110231 GO:0017022 myosin binding 1/170 76/18639 0.0131578947368421 1.44264705882353 0.502302061961851 0.616700699110231 GO:0051536 iron-sulfur cluster binding 1/170 76/18639 0.0131578947368421 1.44264705882353 0.502302061961851 0.616700699110231 GO:0140034 methylation-dependent protein binding 1/170 76/18639 0.0131578947368421 1.44264705882353 0.502302061961851 0.616700699110231 GO:0051540 metal cluster binding 1/170 77/18639 0.012987012987013 1.42391138273491 0.506859980911724 0.620671882630806 GO:0031406 carboxylic acid binding 2/170 187/18639 0.0106951871657754 1.17263290342875 0.510575553631471 0.623593579825938 GO:0140597 protein carrier chaperone 2/170 188/18639 0.0106382978723404 1.16639549436796 0.513421428712773 0.625440649522832 GO:0043177 organic acid binding 2/170 189/18639 0.0105820105820106 1.16022408963585 0.51625647155437 0.627264987458548 GO:0048306 calcium-dependent protein binding 1/170 80/18639 0.0125 1.37051470588235 0.520286248034889 0.630527778626261 GO:0015101 organic cation transmembrane transporter activity 1/170 81/18639 0.0123456790123457 1.35359477124183 0.524680414629753 0.634214212529263 GO:0008135 translation factor activity, RNA binding 1/170 83/18639 0.0120481927710843 1.32097802976612 0.533349062538822 0.641386436745404 GO:0030165 PDZ domain binding 1/170 83/18639 0.0120481927710843 1.32097802976612 0.533349062538822 0.641386436745404 GO:0051117 ATPase binding 1/170 84/18639 0.0119047619047619 1.30525210084034 0.537624265134662 0.643229031500399 GO:0180051 translation factor activity 1/170 84/18639 0.0119047619047619 1.30525210084034 0.537624265134662 0.643229031500399 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/170 86/18639 0.0116279069767442 1.27489740082079 0.546058206535078 0.650003296611553 GO:0050660 flavin adenine dinucleotide binding 1/170 86/18639 0.0116279069767442 1.27489740082079 0.546058206535078 0.650003296611553 GO:0004197 cysteine-type endopeptidase activity 1/170 88/18639 0.0113636363636364 1.24592245989305 0.554339197555119 0.658190085198356 GO:0008168 methyltransferase activity 2/170 204/18639 0.00980392156862745 1.07491349480969 0.557458684766032 0.659698944530238 GO:0003727 single-stranded RNA binding 1/170 89/18639 0.0112359550561798 1.2319233311302 0.558423200380607 0.659698944530238 GO:0005516 calmodulin binding 2/170 207/18639 0.00966183574879227 1.05933503836317 0.565396687949024 0.665737347477008 GO:0043178 alcohol binding 1/170 92/18639 0.0108695652173913 1.19175191815857 0.570453309641089 0.665737347477008 GO:0052689 carboxylic ester hydrolase activity 1/170 92/18639 0.0108695652173913 1.19175191815857 0.570453309641089 0.665737347477008 GO:0004518 nuclease activity 2/170 209/18639 0.00956937799043062 1.04919786096257 0.57063201212315 0.665737347477008 GO:0051015 actin filament binding 2/170 209/18639 0.00956937799043062 1.04919786096257 0.57063201212315 0.665737347477008 GO:0008094 ATP-dependent activity, acting on DNA 2/170 210/18639 0.00952380952380952 1.04420168067227 0.573232630461532 0.667111919817515 GO:0016410 N-acyltransferase activity 1/170 94/18639 0.0106382978723404 1.16639549436796 0.578291798608508 0.669676181598495 GO:0042562 hormone binding 1/170 94/18639 0.0106382978723404 1.16639549436796 0.578291798608508 0.669676181598495 GO:0003924 GTPase activity 3/170 331/18639 0.00906344410876133 0.993726674960014 0.584103342735454 0.673687318542603 GO:0016407 acetyltransferase activity 1/170 96/18639 0.0104166666666667 1.14209558823529 0.585988074744475 0.673687318542603 GO:0016741 transferase activity, transferring one-carbon groups 2/170 215/18639 0.00930232558139535 1.01991792065663 0.586064874126614 0.673687318542603 GO:0008170 N-methyltransferase activity 1/170 98/18639 0.0102040816326531 1.118787515006 0.593544703209065 0.680617275806972 GO:0005261 monoatomic cation channel activity 3/170 341/18639 0.00879765395894428 0.964585130239779 0.604329240042595 0.691293691658481 GO:0015171 amino acid transmembrane transporter activity 1/170 102/18639 0.00980392156862745 1.07491349480969 0.608249048591712 0.694084680753073 GO:0000149 SNARE binding 1/170 106/18639 0.00943396226415094 1.03435072142064 0.622424450724746 0.708536571334723 GO:0005125 cytokine activity 2/170 234/18639 0.00854700854700855 0.93710407239819 0.632224432381471 0.717949779145061 GO:1902936 phosphatidylinositol bisphosphate binding 1/170 111/18639 0.00900900900900901 0.987758346581876 0.639428633767637 0.724376882215028 GO:0005200 structural constituent of cytoskeleton 1/170 112/18639 0.00892857142857143 0.978939075630252 0.642736985033802 0.726370231279164 GO:0005539 glycosaminoglycan binding 2/170 242/18639 0.00826446280991736 0.906125425376762 0.65043215282804 0.732091117273443 GO:0035401 histone H3Y41 kinase activity 1/170 115/18639 0.00869565217391304 0.953401534526854 0.65248206187697 0.732091117273443 GO:0140801 histone H2AXY142 kinase activity 1/170 115/18639 0.00869565217391304 0.953401534526854 0.65248206187697 0.732091117273443 GO:0042277 peptide binding 2/170 249/18639 0.00803212851405622 0.880652019844082 0.665774282100368 0.745222287124278 GO:0032182 ubiquitin-like protein binding 1/170 120/18639 0.00833333333333333 0.913676470588235 0.66814006011336 0.746089733793252 GO:0004540 RNA nuclease activity 1/170 121/18639 0.00826446280991736 0.906125425376762 0.671186455155248 0.747522854657726 GO:0008528 G protein-coupled peptide receptor activity 1/170 122/18639 0.00819672131147541 0.898698167791707 0.674205048017523 0.747522854657726 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/170 122/18639 0.00819672131147541 0.898698167791707 0.674205048017523 0.747522854657726 GO:0001653 peptide receptor activity 1/170 128/18639 0.0078125 0.856571691176471 0.691746726859691 0.763362858581635 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/170 128/18639 0.0078125 0.856571691176471 0.691746726859691 0.763362858581635 GO:0035591 signaling adaptor activity 1/170 129/18639 0.00775193798449612 0.849931600547196 0.694577641258365 0.764687590962848 GO:0005179 hormone activity 1/170 132/18639 0.00757575757575758 0.830614973262032 0.702916239863056 0.770251674055545 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/170 132/18639 0.00757575757575758 0.830614973262032 0.702916239863056 0.770251674055545 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/170 268/18639 0.00746268656716418 0.818217734855136 0.704700919864402 0.770407299338939 GO:0005096 GTPase activator activity 2/170 271/18639 0.00738007380073801 0.809159973952681 0.710492388901997 0.773688336156213 GO:0002020 protease binding 1/170 136/18639 0.00735294117647059 0.806185121107266 0.713683321888215 0.773688336156213 GO:0016779 nucleotidyltransferase activity 1/170 136/18639 0.00735294117647059 0.806185121107266 0.713683321888215 0.773688336156213 GO:0016791 phosphatase activity 2/170 273/18639 0.00732600732600733 0.803232062055591 0.714300745321195 0.773688336156213 GO:1901681 sulfur compound binding 2/170 275/18639 0.00727272727272727 0.797390374331551 0.71806729129144 0.774336418537859 GO:0008017 microtubule binding 2/170 276/18639 0.0072463768115942 0.794501278772379 0.719934964025002 0.774336418537859 GO:0140101 catalytic activity, acting on a tRNA 1/170 139/18639 0.00719424460431655 0.788785442234448 0.721503230066193 0.774336418537859 GO:0140767 enzyme-substrate adaptor activity 1/170 139/18639 0.00719424460431655 0.788785442234448 0.721503230066193 0.774336418537859 GO:0004713 protein tyrosine kinase activity 1/170 140/18639 0.00714285714285714 0.783151260504202 0.724062389573692 0.775308814406534 GO:0030246 carbohydrate binding 2/170 280/18639 0.00714285714285714 0.783151260504202 0.727302402765828 0.777004161496977 GO:0020037 heme binding 1/170 142/18639 0.00704225352112676 0.772120961060481 0.729110782327995 0.777165811163249 GO:0022843 voltage-gated monoatomic cation channel activity 1/170 143/18639 0.00699300699300699 0.766721513780337 0.731600438326494 0.77747942912229 GO:0031267 small GTPase binding 2/170 283/18639 0.00706713780918728 0.774849303679069 0.732720485441475 0.77747942912229 GO:0008509 monoatomic anion transmembrane transporter activity 1/170 149/18639 0.00671140939597315 0.735846821950257 0.746067828061718 0.789855104652248 GO:0046906 tetrapyrrole binding 1/170 152/18639 0.00657894736842105 0.721323529411765 0.753008079008941 0.795407182556741 GO:0005506 iron ion binding 1/170 154/18639 0.00649350649350649 0.711955691367456 0.757529818115813 0.798385358868127 GO:0140375 immune receptor activity 1/170 156/18639 0.00641025641025641 0.702828054298642 0.761969254753896 0.801263633362281 GO:0015079 potassium ion transmembrane transporter activity 1/170 160/18639 0.00625 0.685257352941177 0.770607151132836 0.808534125014094 GO:0015081 sodium ion transmembrane transporter activity 1/170 164/18639 0.00609756097560976 0.668543758967001 0.778933364101121 0.813824045359025 GO:0005216 monoatomic ion channel activity 3/170 448/18639 0.00669642857142857 0.734204306722689 0.779119395237105 0.813824045359025 GO:0016874 ligase activity 1/170 167/18639 0.00598802395209581 0.656533990841846 0.784980223632867 0.816366321551625 GO:0051020 GTPase binding 2/170 315/18639 0.00634920634920635 0.696134453781513 0.785034565074164 0.816366321551625 GO:0005201 extracellular matrix structural constituent 1/170 168/18639 0.00595238095238095 0.652626050420168 0.786959076057207 0.816557094404492 GO:0008201 heparin binding 1/170 172/18639 0.00581395348837209 0.637448700410397 0.794695070506521 0.821095336162113 GO:0005244 voltage-gated monoatomic ion channel activity 1/170 173/18639 0.00578034682080925 0.63376402584155 0.796585027619961 0.821095336162113 GO:0140030 modification-dependent protein binding 1/170 173/18639 0.00578034682080925 0.63376402584155 0.796585027619961 0.821095336162113 GO:0022832 voltage-gated channel activity 1/170 175/18639 0.00571428571428571 0.626521008403361 0.800313208811188 0.823129155553612 GO:0016853 isomerase activity 1/170 180/18639 0.00555555555555556 0.609117647058824 0.80933913082422 0.830590924193783 GO:0140097 catalytic activity, acting on DNA 2/170 336/18639 0.00595238095238095 0.652626050420168 0.814306034905621 0.833863603429555 GO:0008237 metallopeptidase activity 1/170 184/18639 0.00543478260869565 0.595875959079284 0.816266894084204 0.833962922061491 GO:1901981 phosphatidylinositol phosphate binding 1/170 185/18639 0.00540540540540541 0.592655007949126 0.817959369186111 0.833962922061491 GO:0008234 cysteine-type peptidase activity 1/170 187/18639 0.0053475935828877 0.586316451714376 0.821297961916486 0.83526132499672 GO:0046943 carboxylic acid transmembrane transporter activity 1/170 188/18639 0.00531914893617021 0.58319774718398 0.822944360489768 0.83526132499672 GO:0005342 organic acid transmembrane transporter activity 1/170 189/18639 0.00529100529100529 0.580112044817927 0.824575679047935 0.83526132499672 GO:0061659 ubiquitin-like protein ligase activity 2/170 372/18639 0.00537634408602151 0.589468690702087 0.856322045938308 0.865549654191954 GO:0033218 amide binding 1/170 247/18639 0.00404858299595142 0.443891402714932 0.897539421114155 0.90526019032804 GO:0035091 phosphatidylinositol binding 1/170 284/18639 0.00352112676056338 0.38606048053024 0.927357295987973 0.933327407335535 GO:0019787 ubiquitin-like protein transferase activity 2/170 479/18639 0.00417536534446764 0.457791968561955 0.93522762672119 0.939232884223208 GO:0016755 aminoacyltransferase activity 2/170 496/18639 0.00403225806451613 0.442101518026565 0.943153715678544 0.945169001395806 GO:0022836 gated channel activity 1/170 318/18639 0.00314465408805031 0.344783573806881 0.947073774239882 0.947073774239882