ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0004601 peroxidase activity 13/248 57/18639 0.228070175438596 17.1411290322581 4.35489182531764e-13 1.9899550301401e-10 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 13/248 59/18639 0.220338983050847 16.5600738108256 7.03164321604275e-13 1.9899550301401e-10 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 13/248 68/18639 0.191176470588235 14.3682993358634 4.90171584454123e-12 9.24790389336778e-10 GO:0016209 antioxidant activity 13/248 86/18639 0.151162790697674 11.3609808702176 1.10029768422548e-10 1.55692122317905e-08 GO:0009055 electron transfer activity 14/248 116/18639 0.120689655172414 9.07070355951057 4.58236044875991e-10 4.40251196769683e-08 GO:0015078 proton transmembrane transporter activity 17/248 185/18639 0.0918918918918919 6.90634263295554 4.66697381734646e-10 4.40251196769683e-08 GO:0003735 structural constituent of ribosome 16/248 175/18639 0.0914285714285714 6.87152073732719 1.65481259228478e-09 1.33803418176169e-07 GO:0022853 active monoatomic ion transmembrane transporter activity 13/248 118/18639 0.110169491525424 8.28003690541279 6.03465294414253e-09 4.26951695798084e-07 GO:0044389 ubiquitin-like protein ligase binding 19/248 322/18639 0.0590062111801242 4.43474504107393 6.78696159140059e-08 4.26824473414748e-06 GO:0031720 haptoglobin binding 5/248 10/18639 0.5 37.5786290322581 9.55973698693341e-08 5.41081113460431e-06 GO:0031625 ubiquitin protein ligase binding 18/248 302/18639 0.0596026490066225 4.4795716727195 1.30727071634873e-07 6.72650204957618e-06 GO:0015399 primary active transmembrane transporter activity 13/248 166/18639 0.0783132530120482 5.88580936649825 3.55528721232802e-07 1.67691046848138e-05 GO:0045296 cadherin binding 18/248 334/18639 0.0538922155688623 4.05039115317752 5.77357334959916e-07 2.51372501221009e-05 GO:0005344 oxygen carrier activity 5/248 14/18639 0.357142857142857 26.8418778801843 7.27045097823324e-07 2.9393394669143e-05 GO:0004129 cytochrome-c oxidase activity 5/248 15/18639 0.333333333333333 25.0524193548387 1.078745106873e-06 4.07046486993412e-05 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/248 16/18639 0.3125 23.4866431451613 1.55207847923287e-06 5.49047762028626e-05 GO:0008137 NADH dehydrogenase (ubiquinone) activity 6/248 41/18639 0.146341463414634 10.9986231313926 1.5897305207897e-05 0.000529286749862924 GO:0003954 NADH dehydrogenase activity 6/248 44/18639 0.136363636363636 10.2487170087977 2.41393119274505e-05 0.000759047252829834 GO:0043021 ribonucleoprotein complex binding 11/248 177/18639 0.0621468926553672 4.67079004920722 2.59382950932818e-05 0.000772688159094604 GO:0008429 phosphatidylethanolamine binding 4/248 17/18639 0.235294117647059 17.6840607210626 6.35284551756256e-05 0.0017978552814702 GO:0017069 snRNA binding 6/248 54/18639 0.111111111111111 8.3508064516129 7.90407761578538e-05 0.00209176839399582 GO:0019825 oxygen binding 5/248 34/18639 0.147058823529412 11.0525379506641 8.13054852789894e-05 0.00209176839399582 GO:0019888 protein phosphatase regulator activity 8/248 107/18639 0.0747663551401869 5.61923424781429 9.20348971427161e-05 0.00226485877316423 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 6/248 58/18639 0.103448275862069 7.77488876529477 0.000118498468073655 0.00260514304210035 GO:0008135 translation factor activity, RNA binding 7/248 83/18639 0.0843373493975904 6.33856393315196 0.000119177224197392 0.00260514304210035 GO:0003712 transcription coregulator activity 18/248 495/18639 0.0363636363636364 2.73299120234604 0.000119670881792595 0.00260514304210035 GO:0180051 translation factor activity 7/248 84/18639 0.0833333333333333 6.26310483870968 0.000128556822469939 0.00269493190807354 GO:0019208 phosphatase regulator activity 8/248 117/18639 0.0683760683760684 5.13895781637717 0.000171835888686015 0.0034735397498673 GO:0140517 protein-RNA adaptor activity 4/248 22/18639 0.181818181818182 13.6649560117302 0.000185301570272013 0.00361657547496412 GO:0019843 rRNA binding 6/248 65/18639 0.0923076923076923 6.93759305210918 0.000223792431436576 0.00416173624412762 GO:0035198 miRNA binding 5/248 42/18639 0.119047619047619 8.94729262672811 0.00022793961761123 0.00416173624412762 GO:0031072 heat shock protein binding 8/248 131/18639 0.0610687022900763 4.58975621768037 0.000371784848046484 0.00657594449982219 GO:0004857 enzyme inhibitor activity 15/248 416/18639 0.0360576923076923 2.70999728598015 0.000481301847915043 0.00825505593696709 GO:0140104 molecular carrier activity 11/248 249/18639 0.0441767068273092 3.32020015546055 0.000526889327069298 0.00877115762121243 GO:0020037 heme binding 8/248 142/18639 0.0563380281690141 4.23421172194457 0.000636369679154898 0.0102910068114764 GO:0003713 transcription coactivator activity 11/248 256/18639 0.04296875 3.22941343245968 0.000663231686159018 0.0104274759546112 GO:0043022 ribosome binding 7/248 112/18639 0.0625 4.69732862903226 0.000750963976718161 0.0114877192114184 GO:0140297 DNA-binding transcription factor binding 16/248 488/18639 0.0327868852459016 2.46417239555791 0.000874845208481982 0.0130305891579158 GO:0046906 tetrapyrrole binding 8/248 152/18639 0.0526315789473684 3.95564516129032 0.000992662455732738 0.0144063320498649 GO:0061980 regulatory RNA binding 5/248 58/18639 0.0862068965517241 6.47907397107898 0.00103316118125382 0.0146192307147415 GO:0016651 oxidoreductase activity, acting on NAD(P)H 6/248 88/18639 0.0681818181818182 5.12435850439883 0.00113927116135617 0.0154492941904136 GO:0017070 U6 snRNA binding 3/248 16/18639 0.1875 14.0919858870968 0.00114641405653246 0.0154492941904136 GO:0003697 single-stranded DNA binding 7/248 121/18639 0.0578512396694215 4.34794054918688 0.00118347919694966 0.0155778889645002 GO:0022804 active transmembrane transporter activity 15/248 457/18639 0.0328227571115974 2.46686842662526 0.00124746187110781 0.0160468958874323 GO:0098641 cadherin binding involved in cell-cell adhesion 3/248 18/18639 0.166666666666667 12.5262096774194 0.00163798749721038 0.0206022427426905 GO:0042393 histone binding 10/248 247/18639 0.0404858299595142 3.04280397022333 0.00180051615883409 0.0221541770847847 GO:0008301 DNA binding, bending 3/248 19/18639 0.157894736842105 11.866935483871 0.00192611336983244 0.023195322709046 GO:0043024 ribosomal small subunit binding 3/248 20/18639 0.15 11.2735887096774 0.00224389925875382 0.0264593120928055 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 12/248 349/18639 0.0343839541547278 2.58420371568537 0.00258101653790087 0.0293453844407665 GO:0070182 DNA polymerase binding 3/248 21/18639 0.142857142857143 10.7367511520737 0.00259234844883096 0.0293453844407665 GO:0070034 telomerase RNA binding 3/248 22/18639 0.136363636363636 10.2487170087977 0.00297240848228764 0.0329879059014667 GO:0004602 glutathione peroxidase activity 3/248 23/18639 0.130434782608696 9.8031206171108 0.00338497276375794 0.0368441266209037 GO:0005200 structural constituent of cytoskeleton 6/248 112/18639 0.0535714285714286 4.02628168202765 0.00386535509041855 0.0412790751165453 GO:0046332 SMAD binding 5/248 79/18639 0.0632911392405063 4.75678848509596 0.00405697619123349 0.0425231208192251 GO:0001618 virus receptor activity 5/248 81/18639 0.0617283950617284 4.63933691756272 0.00451464004632824 0.046295401778271 GO:0030544 Hsp70 protein binding 4/248 51/18639 0.0784313725490196 5.89468690702087 0.00468358828923795 0.046295401778271 GO:0140272 exogenous protein binding 5/248 82/18639 0.0609756097560976 4.58275963808025 0.0047567340540377 0.046295401778271 GO:0008157 protein phosphatase 1 binding 3/248 26/18639 0.115384615384615 8.67199131513648 0.00482584576840634 0.046295401778271 GO:0070412 R-SMAD binding 3/248 26/18639 0.115384615384615 8.67199131513648 0.00482584576840634 0.046295401778271 GO:0004864 protein phosphatase inhibitor activity 4/248 53/18639 0.0754716981132075 5.67224589166159 0.0053759935774358 0.049882169915224 GO:0016860 intramolecular oxidoreductase activity 4/248 53/18639 0.0754716981132075 5.67224589166159 0.0053759935774358 0.049882169915224 GO:0051082 unfolded protein binding 6/248 121/18639 0.0495867768595041 3.72680618501733 0.00562817933058 0.0513798306630368 GO:0003714 transcription corepressor activity 8/248 204/18639 0.0392156862745098 2.94734345351044 0.00610350048882714 0.0548346234393042 GO:0019212 phosphatase inhibitor activity 4/248 56/18639 0.0714285714285714 5.36837557603687 0.00653781234586337 0.0578187779337292 GO:0072341 modified amino acid binding 5/248 91/18639 0.0549450549450549 4.12951967387451 0.00736561559817979 0.0624724013091244 GO:0030957 Tat protein binding 2/248 10/18639 0.2 15.0314516129032 0.00739514291115077 0.0624724013091244 GO:0098505 G-rich strand telomeric DNA binding 2/248 10/18639 0.2 15.0314516129032 0.00739514291115077 0.0624724013091244 GO:0003730 mRNA 3'-UTR binding 9/248 262/18639 0.0343511450381679 2.58173787244521 0.00864466970121391 0.0704328611164929 GO:0034713 type I transforming growth factor beta receptor binding 2/248 11/18639 0.181818181818182 13.6649560117302 0.00895965724450086 0.0704328611164929 GO:0050786 RAGE receptor binding 2/248 11/18639 0.181818181818182 13.6649560117302 0.00895965724450086 0.0704328611164929 GO:0070990 snRNP binding 2/248 11/18639 0.181818181818182 13.6649560117302 0.00895965724450086 0.0704328611164929 GO:0140537 transcription regulator activator activity 2/248 11/18639 0.181818181818182 13.6649560117302 0.00895965724450086 0.0704328611164929 GO:0019956 chemokine binding 3/248 33/18639 0.0909090909090909 6.8324780058651 0.00945922507796313 0.0733413889606456 GO:0005507 copper ion binding 4/248 63/18639 0.0634920634920635 4.77188940092166 0.00986662330430256 0.075466335003179 GO:0015035 protein-disulfide reductase activity 3/248 34/18639 0.0882352941176471 6.63152277039848 0.0102743180445324 0.0775368535094044 GO:0043047 single-stranded telomeric DNA binding 2/248 12/18639 0.166666666666667 12.5262096774194 0.0106578960636551 0.0783424567795946 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/248 12/18639 0.166666666666667 12.5262096774194 0.0106578960636551 0.0783424567795946 GO:0055106 ubiquitin-protein transferase regulator activity 3/248 36/18639 0.0833333333333333 6.26310483870968 0.012023440728776 0.0872470186216313 GO:0005542 folic acid binding 2/248 13/18639 0.153846153846154 11.5626550868486 0.0124860532978679 0.0894570400834583 GO:1990841 promoter-specific chromatin binding 4/248 68/18639 0.0588235294117647 4.42101518026565 0.0128154414399534 0.0906692481876703 GO:0042162 telomeric DNA binding 3/248 38/18639 0.0789473684210526 5.93346774193548 0.0139331044444334 0.0973007889524628 GO:0016530 metallochaperone activity 2/248 14/18639 0.142857142857143 10.7367511520737 0.0144403997738637 0.0973007889524628 GO:0098847 sequence-specific single stranded DNA binding 2/248 14/18639 0.142857142857143 10.7367511520737 0.0144403997738637 0.0973007889524628 GO:1990825 sequence-specific mRNA binding 2/248 14/18639 0.142857142857143 10.7367511520737 0.0144403997738637 0.0973007889524628 GO:0015036 disulfide oxidoreductase activity 3/248 40/18639 0.075 5.63679435483871 0.0160051858057597 0.105042489112353 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/248 15/18639 0.133333333333333 10.0209677419355 0.0165172818568895 0.105042489112353 GO:0031386 protein tag activity 2/248 15/18639 0.133333333333333 10.0209677419355 0.0165172818568895 0.105042489112353 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/248 15/18639 0.133333333333333 10.0209677419355 0.0165172818568895 0.105042489112353 GO:0141047 molecular tag activity 2/248 15/18639 0.133333333333333 10.0209677419355 0.0165172818568895 0.105042489112353 GO:0003725 double-stranded RNA binding 4/248 75/18639 0.0533333333333333 4.00838709677419 0.0178058939196921 0.111979288428286 GO:0042056 chemoattractant activity 3/248 42/18639 0.0714285714285714 5.36837557603687 0.0182410511418268 0.112222118981239 GO:0048487 beta-tubulin binding 3/248 42/18639 0.0714285714285714 5.36837557603687 0.0182410511418268 0.112222118981239 GO:0098631 cell adhesion mediator activity 4/248 76/18639 0.0526315789473684 3.95564516129032 0.0186043290652723 0.113226346784346 GO:0001046 core promoter sequence-specific DNA binding 3/248 44/18639 0.0681818181818182 5.12435850439883 0.0206415896838342 0.124288720862236 GO:0019887 protein kinase regulator activity 8/248 255/18639 0.0313725490196078 2.35787476280835 0.0211676403037256 0.126114572756934 GO:0000400 four-way junction DNA binding 2/248 18/18639 0.111111111111111 8.3508064516129 0.0234477105626386 0.132714041784534 GO:0000900 mRNA regulatory element binding translation repressor activity 2/248 18/18639 0.111111111111111 8.3508064516129 0.0234477105626386 0.132714041784534 GO:0003746 translation elongation factor activity 2/248 18/18639 0.111111111111111 8.3508064516129 0.0234477105626386 0.132714041784534 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/248 18/18639 0.111111111111111 8.3508064516129 0.0234477105626386 0.132714041784534 GO:0050811 GABA receptor binding 2/248 18/18639 0.111111111111111 8.3508064516129 0.0234477105626386 0.132714041784534 GO:0004860 protein kinase inhibitor activity 4/248 84/18639 0.0476190476190476 3.57891705069124 0.0257913142849446 0.14453350381464 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 12/248 484/18639 0.0247933884297521 1.86340309250866 0.0291370455205305 0.161682036908042 GO:0003743 translation initiation factor activity 3/248 51/18639 0.0588235294117647 4.42101518026565 0.0303430113674597 0.162412161076277 GO:0003727 single-stranded RNA binding 4/248 89/18639 0.0449438202247191 3.37785429503443 0.031022420393975 0.162412161076277 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 4/248 89/18639 0.0449438202247191 3.37785429503443 0.031022420393975 0.162412161076277 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 4/248 89/18639 0.0449438202247191 3.37785429503443 0.031022420393975 0.162412161076277 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/248 21/18639 0.0952380952380952 7.15783410138249 0.0313564041516618 0.162412161076277 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/248 21/18639 0.0952380952380952 7.15783410138249 0.0313564041516618 0.162412161076277 GO:0072542 protein phosphatase activator activity 2/248 21/18639 0.0952380952380952 7.15783410138249 0.0313564041516618 0.162412161076277 GO:0001216 DNA-binding transcription activator activity 12/248 491/18639 0.0244399185336049 1.83683726430589 0.032018285844953 0.162412161076277 GO:0019210 kinase inhibitor activity 4/248 90/18639 0.0444444444444444 3.34032258064516 0.0321380954779912 0.162412161076277 GO:0140793 histone H2AXY142 phosphatase activity 4/248 90/18639 0.0444444444444444 3.34032258064516 0.0321380954779912 0.162412161076277 GO:0051087 protein-folding chaperone binding 5/248 134/18639 0.0373134328358209 2.80437530091478 0.0335790936733309 0.166752308867374 GO:0016853 isomerase activity 6/248 180/18639 0.0333333333333333 2.50524193548387 0.0335861540828279 0.166752308867374 GO:0000287 magnesium ion binding 7/248 230/18639 0.0304347826086957 2.28739481065919 0.0346302059491192 0.170440839714796 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/248 54/18639 0.0555555555555556 4.17540322580645 0.0351159637475086 0.171341685181809 GO:0140789 histone phosphatase activity 5/248 136/18639 0.0367647058823529 2.76313448766603 0.0354513480118008 0.171499683544267 GO:0016922 nuclear receptor binding 5/248 137/18639 0.0364963503649635 2.74296562279256 0.0364111988053221 0.174650326472986 GO:0098632 cell-cell adhesion mediator activity 3/248 55/18639 0.0545454545454545 4.09948680351906 0.0367880183191599 0.174974944274324 GO:0019207 kinase regulator activity 8/248 287/18639 0.0278745644599303 2.09497583455097 0.0387151583545191 0.182606496905482 GO:0019957 C-C chemokine binding 2/248 24/18639 0.0833333333333333 6.26310483870968 0.040156181624666 0.184783730077731 GO:0035035 histone acetyltransferase binding 2/248 24/18639 0.0833333333333333 6.26310483870968 0.040156181624666 0.184783730077731 GO:0048027 mRNA 5'-UTR binding 2/248 24/18639 0.0833333333333333 6.26310483870968 0.040156181624666 0.184783730077731 GO:0004725 protein tyrosine phosphatase activity 4/248 98/18639 0.0408163265306122 3.06764318630678 0.0419048119872306 0.191030321077015 GO:0019211 phosphatase activator activity 2/248 25/18639 0.08 6.01258064516129 0.0432731603418719 0.191030321077015 GO:0019903 protein phosphatase binding 5/248 144/18639 0.0347222222222222 2.60962701612903 0.0435772140711486 0.191030321077015 GO:0019955 cytokine binding 5/248 144/18639 0.0347222222222222 2.60962701612903 0.0435772140711486 0.191030321077015 GO:0001786 phosphatidylserine binding 3/248 59/18639 0.0508474576271186 3.82155549480591 0.0438762221554983 0.191030321077015 GO:0036002 pre-mRNA binding 3/248 59/18639 0.0508474576271186 3.82155549480591 0.0438762221554983 0.191030321077015 GO:0070063 RNA polymerase binding 3/248 59/18639 0.0508474576271186 3.82155549480591 0.0438762221554983 0.191030321077015 GO:0005160 transforming growth factor beta receptor binding 2/248 26/18639 0.0769230769230769 5.78132754342432 0.046477103222994 0.199288185031929 GO:0050681 nuclear androgen receptor binding 2/248 26/18639 0.0769230769230769 5.78132754342432 0.046477103222994 0.199288185031929 GO:0008266 poly(U) RNA binding 2/248 27/18639 0.0740740740740741 5.56720430107527 0.0497651648816989 0.20864506165216 GO:0015252 proton channel activity 2/248 27/18639 0.0740740740740741 5.56720430107527 0.0497651648816989 0.20864506165216 GO:0023026 MHC class II protein complex binding 2/248 27/18639 0.0740740740740741 5.56720430107527 0.0497651648816989 0.20864506165216 GO:0051019 mitogen-activated protein kinase binding 2/248 28/18639 0.0714285714285714 5.36837557603687 0.0531345597126638 0.219519421878596 GO:0097718 disordered domain specific binding 2/248 28/18639 0.0714285714285714 5.36837557603687 0.0531345597126638 0.219519421878596 GO:0005506 iron ion binding 5/248 154/18639 0.0324675324675325 2.44017071638039 0.0551868202371156 0.226345943871068 GO:0008187 poly-pyrimidine tract binding 2/248 30/18639 0.0666666666666667 5.01048387096774 0.0601064989342477 0.244750204293412 GO:0097110 scaffold protein binding 3/248 70/18639 0.0428571428571429 3.22102534562212 0.0665480878837348 0.269044412444242 GO:0051059 NF-kappaB binding 2/248 32/18639 0.0625 4.69732862903226 0.0673717912045484 0.269511117461778 GO:0001221 transcription coregulator binding 4/248 115/18639 0.0347826086956522 2.61416549789621 0.0676158633914707 0.269511117461778 GO:0071889 14-3-3 protein binding 2/248 33/18639 0.0606060606060606 4.5549853372434 0.0711080857933603 0.281448787126167 GO:0005126 cytokine receptor binding 7/248 275/18639 0.0254545454545455 1.91309384164223 0.0754045907388449 0.294182464550315 GO:0003924 GTPase activity 8/248 331/18639 0.0241691842900302 1.81648962089465 0.0757341670110787 0.294182464550315 GO:0003684 damaged DNA binding 3/248 74/18639 0.0405405405405405 3.04691586748038 0.0758845226578552 0.294182464550315 GO:0019003 GDP binding 3/248 75/18639 0.04 3.00629032258065 0.0783044655219454 0.299464514749409 GO:0061631 ubiquitin conjugating enzyme activity 2/248 35/18639 0.0571428571428571 4.29470046082949 0.0787757263599372 0.299464514749409 GO:0001217 DNA-binding transcription repressor activity 7/248 278/18639 0.0251798561151079 1.89244894407055 0.0788342980524064 0.299464514749409 GO:0004721 phosphoprotein phosphatase activity 5/248 175/18639 0.0285714285714286 2.14735023041475 0.0848283047049836 0.320085469753472 GO:0023023 MHC protein complex binding 2/248 37/18639 0.0540540540540541 4.06255448997385 0.0866877174592133 0.320774292864492 GO:0016835 carbon-oxygen lyase activity 3/248 79/18639 0.0379746835443038 2.85407309105757 0.0883147339962081 0.320774292864492 GO:0042826 histone deacetylase binding 4/248 127/18639 0.031496062992126 2.36715773431547 0.0896917717879055 0.320774292864492 GO:0043531 ADP binding 2/248 38/18639 0.0526315789473684 3.95564516129032 0.0907296404044789 0.320774292864492 GO:0048306 calcium-dependent protein binding 3/248 80/18639 0.0375 2.81839717741935 0.0908977084539093 0.320774292864492 GO:0031490 chromatin DNA binding 4/248 128/18639 0.03125 2.34866431451613 0.0916709331249773 0.320774292864492 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 4/248 128/18639 0.03125 2.34866431451613 0.0916709331249773 0.320774292864492 GO:0033192 calmodulin-dependent protein phosphatase activity 3/248 81/18639 0.037037037037037 2.78360215053763 0.0935119404993661 0.320774292864492 GO:0140791 histone H2AXS140 phosphatase activity 3/248 81/18639 0.037037037037037 2.78360215053763 0.0935119404993661 0.320774292864492 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 3/248 81/18639 0.037037037037037 2.78360215053763 0.0935119404993661 0.320774292864492 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 3/248 81/18639 0.037037037037037 2.78360215053763 0.0935119404993661 0.320774292864492 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 3/248 81/18639 0.037037037037037 2.78360215053763 0.0935119404993661 0.320774292864492 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 3/248 81/18639 0.037037037037037 2.78360215053763 0.0935119404993661 0.320774292864492 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 3/248 81/18639 0.037037037037037 2.78360215053763 0.0935119404993661 0.320774292864492 GO:1990439 MAP kinase serine/threonine phosphatase activity 3/248 81/18639 0.037037037037037 2.78360215053763 0.0935119404993661 0.320774292864492 GO:0000217 DNA secondary structure binding 2/248 39/18639 0.0512820512820513 3.85421836228288 0.0948259049690014 0.323322061520812 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 3/248 82/18639 0.0365853658536585 2.74965578284815 0.0961569691862501 0.323957408091771 GO:0033549 MAP kinase phosphatase activity 3/248 82/18639 0.0365853658536585 2.74965578284815 0.0961569691862501 0.323957408091771 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 3/248 83/18639 0.036144578313253 2.71652739992227 0.0988323293978726 0.329526411480816 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/248 40/18639 0.05 3.75786290322581 0.0989743638723299 0.329526411480816 GO:0017018 myosin phosphatase activity 3/248 84/18639 0.0357142857142857 2.68418778801843 0.101537552179833 0.336083359846698 GO:0001530 lipopolysaccharide binding 2/248 41/18639 0.0487804878048781 3.6662077104642 0.103172916937785 0.337548387206857 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/248 41/18639 0.0487804878048781 3.6662077104642 0.103172916937785 0.337548387206857 GO:0031492 nucleosomal DNA binding 2/248 42/18639 0.0476190476190476 3.57891705069124 0.107419510227583 0.347425387364639 GO:0051879 Hsp90 protein binding 2/248 42/18639 0.0476190476190476 3.57891705069124 0.107419510227583 0.347425387364639 GO:0019902 phosphatase binding 5/248 190/18639 0.0263157894736842 1.97782258064516 0.110221716230067 0.354463019239874 GO:0008200 ion channel inhibitor activity 2/248 43/18639 0.0465116279069767 3.4956864216054 0.111712135192487 0.355219486061504 GO:0048156 tau protein binding 2/248 43/18639 0.0465116279069767 3.4956864216054 0.111712135192487 0.355219486061504 GO:0016248 channel inhibitor activity 2/248 44/18639 0.0454545454545455 3.41623900293255 0.116048827835756 0.36694769025161 GO:0141110 transporter inhibitor activity 2/248 45/18639 0.0444444444444444 3.34032258064516 0.120427667891159 0.375513930195331 GO:0001094 TFIID-class transcription factor complex binding 1/248 10/18639 0.1 7.51572580645161 0.125392460789607 0.375513930195331 GO:0005345 purine nucleobase transmembrane transporter activity 1/248 10/18639 0.1 7.51572580645161 0.125392460789607 0.375513930195331 GO:0005522 profilin binding 1/248 10/18639 0.1 7.51572580645161 0.125392460789607 0.375513930195331 GO:0005528 FK506 binding 1/248 10/18639 0.1 7.51572580645161 0.125392460789607 0.375513930195331 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/248 10/18639 0.1 7.51572580645161 0.125392460789607 0.375513930195331 GO:0031434 mitogen-activated protein kinase kinase binding 1/248 10/18639 0.1 7.51572580645161 0.125392460789607 0.375513930195331 GO:0031996 thioesterase binding 1/248 10/18639 0.1 7.51572580645161 0.125392460789607 0.375513930195331 GO:0070513 death domain binding 1/248 10/18639 0.1 7.51572580645161 0.125392460789607 0.375513930195331 GO:1905394 retromer complex binding 1/248 10/18639 0.1 7.51572580645161 0.125392460789607 0.375513930195331 GO:0051219 phosphoprotein binding 3/248 93/18639 0.032258064516129 2.42442767950052 0.127149494988071 0.378352338963759 GO:0001784 phosphotyrosine residue binding 2/248 47/18639 0.0425531914893617 3.19818119423473 0.12930432299078 0.378352338963759 GO:0016410 N-acyltransferase activity 3/248 94/18639 0.0319148936170213 2.39863589567605 0.130126925436312 0.378352338963759 GO:0005525 GTP binding 8/248 378/18639 0.0211640211640212 1.59062980030722 0.132914056420854 0.378352338963759 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/248 48/18639 0.0416666666666667 3.13155241935484 0.133798508949733 0.378352338963759 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/248 11/18639 0.0909090909090909 6.8324780058651 0.137035741144118 0.378352338963759 GO:0005114 type II transforming growth factor beta receptor binding 1/248 11/18639 0.0909090909090909 6.8324780058651 0.137035741144118 0.378352338963759 GO:0005536 D-glucose binding 1/248 11/18639 0.0909090909090909 6.8324780058651 0.137035741144118 0.378352338963759 GO:0010854 adenylate cyclase regulator activity 1/248 11/18639 0.0909090909090909 6.8324780058651 0.137035741144118 0.378352338963759 GO:0015205 nucleobase transmembrane transporter activity 1/248 11/18639 0.0909090909090909 6.8324780058651 0.137035741144118 0.378352338963759 GO:0015217 ADP transmembrane transporter activity 1/248 11/18639 0.0909090909090909 6.8324780058651 0.137035741144118 0.378352338963759 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/248 11/18639 0.0909090909090909 6.8324780058651 0.137035741144118 0.378352338963759 GO:0045294 alpha-catenin binding 1/248 11/18639 0.0909090909090909 6.8324780058651 0.137035741144118 0.378352338963759 GO:0070697 activin receptor binding 1/248 11/18639 0.0909090909090909 6.8324780058651 0.137035741144118 0.378352338963759 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/248 11/18639 0.0909090909090909 6.8324780058651 0.137035741144118 0.378352338963759 GO:1990948 ubiquitin ligase inhibitor activity 1/248 11/18639 0.0909090909090909 6.8324780058651 0.137035741144118 0.378352338963759 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 6/248 268/18639 0.0223880597014925 1.68262518054887 0.148472234198709 0.389189555841252 GO:0003720 telomerase activity 1/248 12/18639 0.0833333333333333 6.26310483870968 0.148524636151432 0.389189555841252 GO:0004859 phospholipase inhibitor activity 1/248 12/18639 0.0833333333333333 6.26310483870968 0.148524636151432 0.389189555841252 GO:0005049 nuclear export signal receptor activity 1/248 12/18639 0.0833333333333333 6.26310483870968 0.148524636151432 0.389189555841252 GO:0005527 macrolide binding 1/248 12/18639 0.0833333333333333 6.26310483870968 0.148524636151432 0.389189555841252 GO:0010853 cyclase activator activity 1/248 12/18639 0.0833333333333333 6.26310483870968 0.148524636151432 0.389189555841252 GO:0016208 AMP binding 1/248 12/18639 0.0833333333333333 6.26310483870968 0.148524636151432 0.389189555841252 GO:0017166 vinculin binding 1/248 12/18639 0.0833333333333333 6.26310483870968 0.148524636151432 0.389189555841252 GO:0035259 nuclear glucocorticoid receptor binding 1/248 12/18639 0.0833333333333333 6.26310483870968 0.148524636151432 0.389189555841252 GO:0035497 cAMP response element binding 1/248 12/18639 0.0833333333333333 6.26310483870968 0.148524636151432 0.389189555841252 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/248 12/18639 0.0833333333333333 6.26310483870968 0.148524636151432 0.389189555841252 GO:0005080 protein kinase C binding 2/248 52/18639 0.0384615384615385 2.89066377171216 0.152107189725116 0.39674041190975 GO:0005246 calcium channel regulator activity 2/248 53/18639 0.0377358490566038 2.8361229458308 0.156759066663442 0.398596610365509 GO:0140296 general transcription initiation factor binding 2/248 53/18639 0.0377358490566038 2.8361229458308 0.156759066663442 0.398596610365509 GO:0004722 protein serine/threonine phosphatase activity 3/248 103/18639 0.029126213592233 2.18904635139367 0.157968831145533 0.398596610365509 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/248 13/18639 0.0769230769230769 5.78132754342432 0.159861184722563 0.398596610365509 GO:0003964 RNA-directed DNA polymerase activity 1/248 13/18639 0.0769230769230769 5.78132754342432 0.159861184722563 0.398596610365509 GO:0019104 DNA N-glycosylase activity 1/248 13/18639 0.0769230769230769 5.78132754342432 0.159861184722563 0.398596610365509 GO:0019855 calcium channel inhibitor activity 1/248 13/18639 0.0769230769230769 5.78132754342432 0.159861184722563 0.398596610365509 GO:0030955 potassium ion binding 1/248 13/18639 0.0769230769230769 5.78132754342432 0.159861184722563 0.398596610365509 GO:0031432 titin binding 1/248 13/18639 0.0769230769230769 5.78132754342432 0.159861184722563 0.398596610365509 GO:0089720 caspase binding 1/248 13/18639 0.0769230769230769 5.78132754342432 0.159861184722563 0.398596610365509 GO:0003925 G protein activity 2/248 54/18639 0.037037037037037 2.78360215053763 0.161437647544824 0.400761879431448 GO:0019001 guanyl nucleotide binding 8/248 400/18639 0.02 1.50314516129032 0.165627084198347 0.407082408832237 GO:0032561 guanyl ribonucleotide binding 8/248 400/18639 0.02 1.50314516129032 0.165627084198347 0.407082408832237 GO:0140313 molecular sequestering activity 2/248 55/18639 0.0363636363636364 2.73299120234604 0.166141407138245 0.407082408832237 GO:0005178 integrin binding 4/248 161/18639 0.0248447204968944 1.86726106992587 0.167556705407813 0.408780583020786 GO:0005347 ATP transmembrane transporter activity 1/248 14/18639 0.0714285714285714 5.36837557603687 0.171047398949386 0.410223846632849 GO:0008494 translation activator activity 1/248 14/18639 0.0714285714285714 5.36837557603687 0.171047398949386 0.410223846632849 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/248 14/18639 0.0714285714285714 5.36837557603687 0.171047398949386 0.410223846632849 GO:0043176 amine binding 1/248 14/18639 0.0714285714285714 5.36837557603687 0.171047398949386 0.410223846632849 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/248 15/18639 0.0666666666666667 5.01048387096774 0.182085264455992 0.433026301185259 GO:0017081 chloride channel regulator activity 1/248 15/18639 0.0666666666666667 5.01048387096774 0.182085264455992 0.433026301185259 GO:0015459 potassium channel regulator activity 2/248 59/18639 0.0338983050847458 2.54770366320394 0.185178958471759 0.436601066519634 GO:0045309 protein phosphorylated amino acid binding 2/248 59/18639 0.0338983050847458 2.54770366320394 0.185178958471759 0.436601066519634 GO:0016247 channel regulator activity 4/248 168/18639 0.0238095238095238 1.78945852534562 0.185902574260127 0.436601066519634 GO:0141108 transporter regulator activity 4/248 170/18639 0.0235294117647059 1.76840607210626 0.19126100186712 0.438653956875206 GO:0005149 interleukin-1 receptor binding 1/248 16/18639 0.0625 4.69732862903226 0.192976740745453 0.438653956875206 GO:0005521 lamin binding 1/248 16/18639 0.0625 4.69732862903226 0.192976740745453 0.438653956875206 GO:0008296 3'-5'-DNA exonuclease activity 1/248 16/18639 0.0625 4.69732862903226 0.192976740745453 0.438653956875206 GO:0034450 ubiquitin-ubiquitin ligase activity 1/248 16/18639 0.0625 4.69732862903226 0.192976740745453 0.438653956875206 GO:0043023 ribosomal large subunit binding 1/248 16/18639 0.0625 4.69732862903226 0.192976740745453 0.438653956875206 GO:0055102 lipase inhibitor activity 1/248 16/18639 0.0625 4.69732862903226 0.192976740745453 0.438653956875206 GO:0070411 I-SMAD binding 1/248 16/18639 0.0625 4.69732862903226 0.192976740745453 0.438653956875206 GO:0016836 hydro-lyase activity 2/248 61/18639 0.0327868852459016 2.46417239555791 0.194811701282562 0.44105369170372 GO:0005125 cytokine activity 5/248 234/18639 0.0213675213675214 1.60592431761787 0.202113201389817 0.448667895069274 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/248 17/18639 0.0588235294117647 4.42101518026565 0.203723761542056 0.448667895069274 GO:0005092 GDP-dissociation inhibitor activity 1/248 17/18639 0.0588235294117647 4.42101518026565 0.203723761542056 0.448667895069274 GO:0019198 transmembrane receptor protein phosphatase activity 1/248 17/18639 0.0588235294117647 4.42101518026565 0.203723761542056 0.448667895069274 GO:0045236 CXCR chemokine receptor binding 1/248 17/18639 0.0588235294117647 4.42101518026565 0.203723761542056 0.448667895069274 GO:0048038 quinone binding 1/248 17/18639 0.0588235294117647 4.42101518026565 0.203723761542056 0.448667895069274 GO:1990226 histone methyltransferase binding 1/248 17/18639 0.0588235294117647 4.42101518026565 0.203723761542056 0.448667895069274 GO:0004706 JUN kinase kinase kinase activity 1/248 18/18639 0.0555555555555556 4.17540322580645 0.21432823512908 0.46657608108869 GO:0017128 phospholipid scramblase activity 1/248 18/18639 0.0555555555555556 4.17540322580645 0.21432823512908 0.46657608108869 GO:1990381 ubiquitin-specific protease binding 1/248 18/18639 0.0555555555555556 4.17540322580645 0.21432823512908 0.46657608108869 GO:0005543 phospholipid binding 9/248 497/18639 0.0181086519114688 1.36099662491075 0.21852964500488 0.47389953667725 GO:0004674 protein serine/threonine kinase activity 8/248 433/18639 0.0184757505773672 1.38858675407882 0.220800248275371 0.47699595619794 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/248 19/18639 0.0526315789473684 3.95564516129032 0.224792044682165 0.478316907105659 GO:0031420 alkali metal ion binding 1/248 19/18639 0.0526315789473684 3.95564516129032 0.224792044682165 0.478316907105659 GO:0050145 nucleoside monophosphate kinase activity 1/248 19/18639 0.0526315789473684 3.95564516129032 0.224792044682165 0.478316907105659 GO:0097001 ceramide binding 1/248 19/18639 0.0526315789473684 3.95564516129032 0.224792044682165 0.478316907105659 GO:0002039 p53 binding 2/248 69/18639 0.0289855072463768 2.17847124824684 0.233864292688019 0.492874998172776 GO:0008080 N-acetyltransferase activity 2/248 69/18639 0.0289855072463768 2.17847124824684 0.233864292688019 0.492874998172776 GO:0010851 cyclase regulator activity 1/248 20/18639 0.05 3.75786290322581 0.235117048598321 0.492874998172776 GO:0042288 MHC class I protein binding 1/248 20/18639 0.05 3.75786290322581 0.235117048598321 0.492874998172776 GO:0010314 phosphatidylinositol-5-phosphate binding 1/248 21/18639 0.0476190476190476 3.57891705069124 0.245305080820653 0.512334596843136 GO:0043539 protein serine/threonine kinase activator activity 2/248 73/18639 0.0273972602739726 2.05910296067167 0.253575647002615 0.525901511752143 GO:0015631 tubulin binding 7/248 385/18639 0.0181818181818182 1.36649560117302 0.253659209732041 0.525901511752143 GO:0031491 nucleosome binding 2/248 74/18639 0.027027027027027 2.03127724498692 0.258511511567747 0.534005531194688 GO:0000295 adenine nucleotide transmembrane transporter activity 1/248 23/18639 0.0434782608695652 3.26770687237027 0.26527744560546 0.538709255649918 GO:0016493 C-C chemokine receptor activity 1/248 23/18639 0.0434782608695652 3.26770687237027 0.26527744560546 0.538709255649918 GO:0043274 phospholipase binding 1/248 23/18639 0.0434782608695652 3.26770687237027 0.26527744560546 0.538709255649918 GO:0099186 structural constituent of postsynapse 1/248 23/18639 0.0434782608695652 3.26770687237027 0.26527744560546 0.538709255649918 GO:0002020 protease binding 3/248 136/18639 0.0220588235294118 1.65788069259962 0.271384299341931 0.538709255649918 GO:0003724 RNA helicase activity 2/248 77/18639 0.025974025974026 1.95213657310431 0.273323397335761 0.538709255649918 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/248 24/18639 0.0416666666666667 3.13155241935484 0.275065326648103 0.538709255649918 GO:0005315 phosphate transmembrane transporter activity 1/248 24/18639 0.0416666666666667 3.13155241935484 0.275065326648103 0.538709255649918 GO:0015149 hexose transmembrane transporter activity 1/248 24/18639 0.0416666666666667 3.13155241935484 0.275065326648103 0.538709255649918 GO:0015295 solute:proton symporter activity 1/248 24/18639 0.0416666666666667 3.13155241935484 0.275065326648103 0.538709255649918 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/248 24/18639 0.0416666666666667 3.13155241935484 0.275065326648103 0.538709255649918 GO:0050431 transforming growth factor beta binding 1/248 24/18639 0.0416666666666667 3.13155241935484 0.275065326648103 0.538709255649918 GO:0055056 D-glucose transmembrane transporter activity 1/248 24/18639 0.0416666666666667 3.13155241935484 0.275065326648103 0.538709255649918 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/248 24/18639 0.0416666666666667 3.13155241935484 0.275065326648103 0.538709255649918 GO:0070840 dynein complex binding 1/248 24/18639 0.0416666666666667 3.13155241935484 0.275065326648103 0.538709255649918 GO:0016829 lyase activity 4/248 200/18639 0.02 1.50314516129032 0.27642198023988 0.539499451088869 GO:0008186 ATP-dependent activity, acting on RNA 2/248 79/18639 0.0253164556962025 1.90271539403838 0.28319280690245 0.544272226993818 GO:0004709 MAP kinase kinase kinase activity 1/248 25/18639 0.04 3.00629032258065 0.284723333577529 0.544272226993818 GO:0008139 nuclear localization sequence binding 1/248 25/18639 0.04 3.00629032258065 0.284723333577529 0.544272226993818 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/248 25/18639 0.04 3.00629032258065 0.284723333577529 0.544272226993818 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/248 25/18639 0.04 3.00629032258065 0.284723333577529 0.544272226993818 GO:0120020 cholesterol transfer activity 1/248 25/18639 0.04 3.00629032258065 0.284723333577529 0.544272226993818 GO:0001637 G protein-coupled chemoattractant receptor activity 1/248 26/18639 0.0384615384615385 2.89066377171216 0.294253182791711 0.544272226993818 GO:0004529 DNA exonuclease activity 1/248 26/18639 0.0384615384615385 2.89066377171216 0.294253182791711 0.544272226993818 GO:0004950 chemokine receptor activity 1/248 26/18639 0.0384615384615385 2.89066377171216 0.294253182791711 0.544272226993818 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/248 26/18639 0.0384615384615385 2.89066377171216 0.294253182791711 0.544272226993818 GO:0008143 poly(A) binding 1/248 26/18639 0.0384615384615385 2.89066377171216 0.294253182791711 0.544272226993818 GO:0008198 ferrous iron binding 1/248 26/18639 0.0384615384615385 2.89066377171216 0.294253182791711 0.544272226993818 GO:0015145 monosaccharide transmembrane transporter activity 1/248 26/18639 0.0384615384615385 2.89066377171216 0.294253182791711 0.544272226993818 GO:0015216 purine nucleotide transmembrane transporter activity 1/248 26/18639 0.0384615384615385 2.89066377171216 0.294253182791711 0.544272226993818 GO:0050750 low-density lipoprotein particle receptor binding 1/248 26/18639 0.0384615384615385 2.89066377171216 0.294253182791711 0.544272226993818 GO:0097602 cullin family protein binding 1/248 26/18639 0.0384615384615385 2.89066377171216 0.294253182791711 0.544272226993818 GO:0016791 phosphatase activity 5/248 273/18639 0.0183150183150183 1.37650655795817 0.29873961209844 0.550770750644029 GO:0001671 ATPase activator activity 1/248 27/18639 0.037037037037037 2.78360215053763 0.303656568095942 0.554418121104204 GO:0008320 protein transmembrane transporter activity 1/248 27/18639 0.037037037037037 2.78360215053763 0.303656568095942 0.554418121104204 GO:0035255 ionotropic glutamate receptor binding 1/248 27/18639 0.037037037037037 2.78360215053763 0.303656568095942 0.554418121104204 GO:0008017 microtubule binding 5/248 276/18639 0.0181159420289855 1.36154453015428 0.306513152716627 0.557834226487495 GO:0019789 SUMO transferase activity 1/248 28/18639 0.0357142857142857 2.68418778801843 0.312935160999026 0.558742274843688 GO:0046625 sphingolipid binding 1/248 28/18639 0.0357142857142857 2.68418778801843 0.312935160999026 0.558742274843688 GO:0051119 sugar transmembrane transporter activity 1/248 28/18639 0.0357142857142857 2.68418778801843 0.312935160999026 0.558742274843688 GO:0051537 2 iron, 2 sulfur cluster binding 1/248 28/18639 0.0357142857142857 2.68418778801843 0.312935160999026 0.558742274843688 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/248 28/18639 0.0357142857142857 2.68418778801843 0.312935160999026 0.558742274843688 GO:0141052 histone H3 demethylase activity 1/248 28/18639 0.0357142857142857 2.68418778801843 0.312935160999026 0.558742274843688 GO:0043236 laminin binding 1/248 29/18639 0.0344827586206897 2.59162958843159 0.322090611005595 0.569817819394891 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/248 29/18639 0.0344827586206897 2.59162958843159 0.322090611005595 0.569817819394891 GO:0019842 vitamin binding 3/248 150/18639 0.02 1.50314516129032 0.322158484463543 0.569817819394891 GO:0015215 nucleotide transmembrane transporter activity 1/248 30/18639 0.0333333333333333 2.50524193548387 0.331124545904606 0.573139122269135 GO:0016769 transferase activity, transferring nitrogenous groups 1/248 30/18639 0.0333333333333333 2.50524193548387 0.331124545904606 0.573139122269135 GO:0032452 histone demethylase activity 1/248 30/18639 0.0333333333333333 2.50524193548387 0.331124545904606 0.573139122269135 GO:0033612 receptor serine/threonine kinase binding 1/248 30/18639 0.0333333333333333 2.50524193548387 0.331124545904606 0.573139122269135 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/248 30/18639 0.0333333333333333 2.50524193548387 0.331124545904606 0.573139122269135 GO:0051721 protein phosphatase 2A binding 1/248 30/18639 0.0333333333333333 2.50524193548387 0.331124545904606 0.573139122269135 GO:0098918 structural constituent of synapse 1/248 30/18639 0.0333333333333333 2.50524193548387 0.331124545904606 0.573139122269135 GO:0047499 calcium-independent phospholipase A2 activity 1/248 31/18639 0.032258064516129 2.42442767950052 0.340038572054086 0.581455685143844 GO:0070273 phosphatidylinositol-4-phosphate binding 1/248 31/18639 0.032258064516129 2.42442767950052 0.340038572054086 0.581455685143844 GO:0070325 lipoprotein particle receptor binding 1/248 31/18639 0.032258064516129 2.42442767950052 0.340038572054086 0.581455685143844 GO:0140457 protein demethylase activity 1/248 31/18639 0.032258064516129 2.42442767950052 0.340038572054086 0.581455685143844 GO:0022884 macromolecule transmembrane transporter activity 1/248 32/18639 0.03125 2.34866431451613 0.348834274662135 0.585875962785664 GO:0030515 snoRNA binding 1/248 32/18639 0.03125 2.34866431451613 0.348834274662135 0.585875962785664 GO:0047498 calcium-dependent phospholipase A2 activity 1/248 32/18639 0.03125 2.34866431451613 0.348834274662135 0.585875962785664 GO:0070717 poly-purine tract binding 1/248 32/18639 0.03125 2.34866431451613 0.348834274662135 0.585875962785664 GO:0120015 sterol transfer activity 1/248 32/18639 0.03125 2.34866431451613 0.348834274662135 0.585875962785664 GO:0140142 nucleocytoplasmic carrier activity 1/248 32/18639 0.03125 2.34866431451613 0.348834274662135 0.585875962785664 GO:0051213 dioxygenase activity 2/248 93/18639 0.021505376344086 1.61628511966701 0.351618702683557 0.588805283191992 GO:0042578 phosphoric ester hydrolase activity 6/248 363/18639 0.0165289256198347 1.24226872833911 0.353689240600153 0.590525398760138 GO:0140311 protein sequestering activity 1/248 33/18639 0.0303030303030303 2.2774926686217 0.357513218064285 0.593342955952147 GO:0140416 transcription regulator inhibitor activity 1/248 33/18639 0.0303030303030303 2.2774926686217 0.357513218064285 0.593342955952147 GO:0099106 ion channel regulator activity 3/248 160/18639 0.01875 1.40919858870968 0.358521715433983 0.593342955952147 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4/248 229/18639 0.0174672489082969 1.31279053387801 0.363396010868674 0.598842634203533 GO:0016407 acetyltransferase activity 2/248 96/18639 0.0208333333333333 1.56577620967742 0.36602495555673 0.598842634203533 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/248 34/18639 0.0294117647058824 2.21050759013283 0.366076945997213 0.598842634203533 GO:0090482 vitamin transmembrane transporter activity 1/248 34/18639 0.0294117647058824 2.21050759013283 0.366076945997213 0.598842634203533 GO:0140713 histone chaperone activity 3/248 164/18639 0.0182926829268293 1.37482789142408 0.37300583635046 0.605663633536559 GO:0004623 phospholipase A2 activity 1/248 35/18639 0.0285714285714286 2.14735023041475 0.374526981868897 0.605663633536559 GO:0005154 epidermal growth factor receptor binding 1/248 35/18639 0.0285714285714286 2.14735023041475 0.374526981868897 0.605663633536559 GO:0034061 DNA polymerase activity 1/248 35/18639 0.0285714285714286 2.14735023041475 0.374526981868897 0.605663633536559 GO:0003779 actin binding 7/248 443/18639 0.0158013544018059 1.1875864705454 0.376369178177788 0.606908703272445 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/248 36/18639 0.0277777777777778 2.08770161290323 0.382864829025235 0.608535525360331 GO:0045505 dynein intermediate chain binding 1/248 36/18639 0.0277777777777778 2.08770161290323 0.382864829025235 0.608535525360331 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/248 36/18639 0.0277777777777778 2.08770161290323 0.382864829025235 0.608535525360331 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/248 36/18639 0.0277777777777778 2.08770161290323 0.382864829025235 0.608535525360331 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/248 36/18639 0.0277777777777778 2.08770161290323 0.382864829025235 0.608535525360331 GO:0016874 ligase activity 3/248 167/18639 0.0179640718562874 1.35013038439251 0.383828944441057 0.608535525360331 GO:0043130 ubiquitin binding 2/248 100/18639 0.02 1.50314516129032 0.385038152548678 0.608747470230591 GO:0030414 peptidase inhibitor activity 3/248 169/18639 0.0177514792899408 1.334152510021 0.391021316493264 0.6164848611008 GO:0000146 microfilament motor activity 1/248 38/18639 0.0263157894736842 1.97782258064516 0.399209871840442 0.627646631838028 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/248 39/18639 0.0256410256410256 1.92710918114144 0.407219976231796 0.633315417232436 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/248 39/18639 0.0256410256410256 1.92710918114144 0.407219976231796 0.633315417232436 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/248 39/18639 0.0256410256410256 1.92710918114144 0.407219976231796 0.633315417232436 GO:0000149 SNARE binding 2/248 106/18639 0.0188679245283019 1.4180614729154 0.413081614699449 0.633315417232436 GO:0015144 carbohydrate transmembrane transporter activity 1/248 40/18639 0.025 1.8789314516129 0.415123709882039 0.633315417232436 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/248 40/18639 0.025 1.8789314516129 0.415123709882039 0.633315417232436 GO:0030331 nuclear estrogen receptor binding 1/248 40/18639 0.025 1.8789314516129 0.415123709882039 0.633315417232436 GO:0032451 demethylase activity 1/248 40/18639 0.025 1.8789314516129 0.415123709882039 0.633315417232436 GO:0061791 GTPase motor activity 1/248 40/18639 0.025 1.8789314516129 0.415123709882039 0.633315417232436 GO:0140662 ATP-dependent protein folding chaperone 1/248 40/18639 0.025 1.8789314516129 0.415123709882039 0.633315417232436 GO:1990606 membrane scission GTPase motor activity 1/248 40/18639 0.025 1.8789314516129 0.415123709882039 0.633315417232436 GO:0033218 amide binding 4/248 247/18639 0.0161943319838057 1.21712158808933 0.417491772376804 0.633512984357295 GO:0035402 histone H3T11 kinase activity 4/248 247/18639 0.0161943319838057 1.21712158808933 0.417491772376804 0.633512984357295 GO:0017080 sodium channel regulator activity 1/248 41/18639 0.024390243902439 1.8331038552321 0.422922479705645 0.636633307216476 GO:0042287 MHC protein binding 1/248 41/18639 0.024390243902439 1.8331038552321 0.422922479705645 0.636633307216476 GO:0140318 protein transporter activity 1/248 41/18639 0.024390243902439 1.8331038552321 0.422922479705645 0.636633307216476 GO:0004402 histone acetyltransferase activity 1/248 42/18639 0.0238095238095238 1.78945852534562 0.430617674083159 0.639710245488367 GO:0004520 DNA endonuclease activity 1/248 42/18639 0.0238095238095238 1.78945852534562 0.430617674083159 0.639710245488367 GO:0008307 structural constituent of muscle 1/248 42/18639 0.0238095238095238 1.78945852534562 0.430617674083159 0.639710245488367 GO:0016859 cis-trans isomerase activity 1/248 42/18639 0.0238095238095238 1.78945852534562 0.430617674083159 0.639710245488367 GO:0019894 kinesin binding 1/248 42/18639 0.0238095238095238 1.78945852534562 0.430617674083159 0.639710245488367 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/248 43/18639 0.0232558139534884 1.7478432108027 0.438210663104365 0.647590692733866 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/248 43/18639 0.0232558139534884 1.7478432108027 0.438210663104365 0.647590692733866 GO:0001223 transcription coactivator binding 1/248 44/18639 0.0227272727272727 1.70811950146628 0.445702798808286 0.651854739342352 GO:0019205 nucleobase-containing compound kinase activity 1/248 44/18639 0.0227272727272727 1.70811950146628 0.445702798808286 0.651854739342352 GO:0030547 signaling receptor inhibitor activity 1/248 44/18639 0.0227272727272727 1.70811950146628 0.445702798808286 0.651854739342352 GO:0043014 alpha-tubulin binding 1/248 44/18639 0.0227272727272727 1.70811950146628 0.445702798808286 0.651854739342352 GO:0008009 chemokine activity 1/248 45/18639 0.0222222222222222 1.67016129032258 0.453095415420039 0.658759824963061 GO:0140303 intramembrane lipid transporter activity 1/248 45/18639 0.0222222222222222 1.67016129032258 0.453095415420039 0.658759824963061 GO:0017124 SH3 domain binding 2/248 115/18639 0.0173913043478261 1.30708274894811 0.453915780451579 0.658759824963061 GO:0140597 protein carrier chaperone 3/248 188/18639 0.0159574468085106 1.19931794783802 0.45805086239315 0.663060839167578 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/248 46/18639 0.0217391304347826 1.63385343618513 0.460389829584599 0.664746539655314 GO:0140097 catalytic activity, acting on DNA 5/248 336/18639 0.0148809523809524 1.11841157834101 0.46370793380018 0.667833818144789 GO:0043495 protein-membrane adaptor activity 1/248 47/18639 0.0212765957446809 1.59909059711736 0.467587340597509 0.670011227286556 GO:0061733 protein-lysine-acetyltransferase activity 1/248 47/18639 0.0212765957446809 1.59909059711736 0.467587340597509 0.670011227286556 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/248 48/18639 0.0208333333333333 1.56577620967742 0.474689230632568 0.675060564165913 GO:0032266 phosphatidylinositol-3-phosphate binding 1/248 48/18639 0.0208333333333333 1.56577620967742 0.474689230632568 0.675060564165913 GO:0140693 molecular condensate scaffold activity 1/248 48/18639 0.0208333333333333 1.56577620967742 0.474689230632568 0.675060564165913 GO:0032182 ubiquitin-like protein binding 2/248 120/18639 0.0166666666666667 1.25262096774194 0.475893177490485 0.675076537492769 GO:0001222 transcription corepressor binding 1/248 49/18639 0.0204081632653061 1.53382159315339 0.481696764966553 0.676526970151536 GO:0016763 pentosyltransferase activity 1/248 49/18639 0.0204081632653061 1.53382159315339 0.481696764966553 0.676526970151536 GO:0035254 glutamate receptor binding 1/248 49/18639 0.0204081632653061 1.53382159315339 0.481696764966553 0.676526970151536 GO:0060590 ATPase regulator activity 1/248 49/18639 0.0204081632653061 1.53382159315339 0.481696764966553 0.676526970151536 GO:0015605 organophosphate ester transmembrane transporter activity 1/248 50/18639 0.02 1.50314516129032 0.488611192200996 0.684539442539019 GO:0005048 signal sequence binding 1/248 51/18639 0.0196078431372549 1.47367172675522 0.495433744481062 0.692383949077238 GO:0005544 calcium-dependent phospholipid binding 1/248 53/18639 0.0188679245283019 1.4180614729154 0.508808071770189 0.704120705677083 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/248 53/18639 0.0188679245283019 1.4180614729154 0.508808071770189 0.704120705677083 GO:0034212 protein N-acetyltransferase activity 1/248 53/18639 0.0188679245283019 1.4180614729154 0.508808071770189 0.704120705677083 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/248 53/18639 0.0188679245283019 1.4180614729154 0.508808071770189 0.704120705677083 GO:0015485 cholesterol binding 1/248 54/18639 0.0185185185185185 1.39180107526882 0.515362230717837 0.707997627636641 GO:0050661 NADP binding 1/248 54/18639 0.0185185185185185 1.39180107526882 0.515362230717837 0.707997627636641 GO:0051287 NAD binding 1/248 54/18639 0.0185185185185185 1.39180107526882 0.515362230717837 0.707997627636641 GO:0005516 calmodulin binding 3/248 207/18639 0.0144927536231884 1.08923562412342 0.521790177425806 0.713418778216409 GO:0008374 O-acyltransferase activity 1/248 55/18639 0.0181818181818182 1.36649560117302 0.521829283006348 0.713418778216409 GO:0106310 protein serine kinase activity 5/248 361/18639 0.0138504155124654 1.04095925297114 0.526730036279863 0.717020354339577 GO:0030170 pyridoxal phosphate binding 1/248 56/18639 0.0178571428571429 1.34209389400922 0.528210381683405 0.717020354339577 GO:0051015 actin filament binding 3/248 209/18639 0.0143540669856459 1.07881231671554 0.528264112649477 0.717020354339577 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/248 57/18639 0.0175438596491228 1.31854838709677 0.534506664594803 0.722030482483673 GO:0070279 vitamin B6 binding 1/248 57/18639 0.0175438596491228 1.31854838709677 0.534506664594803 0.722030482483673 GO:0008408 3'-5' exonuclease activity 1/248 58/18639 0.0172413793103448 1.2958147942158 0.540719254584067 0.727580965262773 GO:0019838 growth factor binding 2/248 136/18639 0.0147058823529412 1.10525379506641 0.542472027104046 0.727580965262773 GO:0044325 transmembrane transporter binding 2/248 136/18639 0.0147058823529412 1.10525379506641 0.542472027104046 0.727580965262773 GO:0046982 protein heterodimerization activity 5/248 369/18639 0.013550135501355 1.0183910306845 0.546223577930605 0.729598096723037 GO:0070888 E-box binding 1/248 59/18639 0.0169491525423729 1.27385183160197 0.546849259689452 0.729598096723037 GO:0001098 basal transcription machinery binding 1/248 60/18639 0.0166666666666667 1.25262096774194 0.552897773338376 0.729598096723037 GO:0001099 basal RNA polymerase II transcription machinery binding 1/248 60/18639 0.0166666666666667 1.25262096774194 0.552897773338376 0.729598096723037 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/248 60/18639 0.0166666666666667 1.25262096774194 0.552897773338376 0.729598096723037 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/248 60/18639 0.0166666666666667 1.25262096774194 0.552897773338376 0.729598096723037 GO:0030295 protein kinase activator activity 2/248 139/18639 0.0143884892086331 1.08139939661174 0.554288306697714 0.729598096723037 GO:0070851 growth factor receptor binding 2/248 139/18639 0.0143884892086331 1.08139939661174 0.554288306697714 0.729598096723037 GO:0015026 coreceptor activity 1/248 61/18639 0.0163934426229508 1.23208619777895 0.558865874539306 0.733444077972427 GO:0001664 G protein-coupled receptor binding 4/248 297/18639 0.0134680134680135 1.01221896383187 0.559801840431251 0.733444077972427 GO:0004536 DNA nuclease activity 1/248 64/18639 0.015625 1.17433215725806 0.576298281214089 0.740116923672261 GO:0061134 peptidase regulator activity 3/248 226/18639 0.0132743362831858 0.997662717670568 0.581255125428542 0.740116923672261 GO:0120013 lipid transfer activity 1/248 65/18639 0.0153846153846154 1.15626550868486 0.581955240905013 0.740116923672261 GO:0019209 kinase activator activity 2/248 148/18639 0.0135135135135135 1.01563862249346 0.588432930872242 0.740116923672261 GO:0140098 catalytic activity, acting on RNA 5/248 387/18639 0.0129198966408269 0.9710240060015 0.588636276853309 0.740116923672261 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/248 67/18639 0.0149253731343284 1.12175012036591 0.593044475229456 0.740116923672261 GO:0050840 extracellular matrix binding 1/248 67/18639 0.0149253731343284 1.12175012036591 0.593044475229456 0.740116923672261 GO:0005085 guanyl-nucleotide exchange factor activity 3/248 230/18639 0.0130434782608696 0.98031206171108 0.593167787159277 0.740116923672261 GO:0005548 phospholipid transporter activity 1/248 68/18639 0.0147058823529412 1.10525379506641 0.598478729490876 0.740116923672261 GO:0030145 manganese ion binding 1/248 68/18639 0.0147058823529412 1.10525379506641 0.598478729490876 0.740116923672261 GO:0032934 sterol binding 1/248 68/18639 0.0147058823529412 1.10525379506641 0.598478729490876 0.740116923672261 GO:0140223 general transcription initiation factor activity 1/248 68/18639 0.0147058823529412 1.10525379506641 0.598478729490876 0.740116923672261 GO:0000510 H3-H4 histone complex chaperone activity 2/248 151/18639 0.0132450331125828 0.995460371715445 0.599376713998429 0.740116923672261 GO:0140584 chromatin extrusion motor activity 2/248 151/18639 0.0132450331125828 0.995460371715445 0.599376713998429 0.740116923672261 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/248 151/18639 0.0132450331125828 0.995460371715445 0.599376713998429 0.740116923672261 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/248 151/18639 0.0132450331125828 0.995460371715445 0.599376713998429 0.740116923672261 GO:0015616 DNA translocase activity 2/248 152/18639 0.0131578947368421 0.988911290322581 0.602975884480021 0.740116923672261 GO:0140674 ATP-dependent histone chaperone activity 2/248 152/18639 0.0131578947368421 0.988911290322581 0.602975884480021 0.740116923672261 GO:0051020 GTPase binding 4/248 315/18639 0.0126984126984127 0.954377880184332 0.606325766360111 0.740116923672261 GO:0003774 cytoskeletal motor activity 2/248 153/18639 0.0130718954248366 0.982447817836812 0.606550680461847 0.740116923672261 GO:0061775 cohesin loader activity 2/248 153/18639 0.0130718954248366 0.982447817836812 0.606550680461847 0.740116923672261 GO:0004386 helicase activity 2/248 155/18639 0.0129032258064516 0.969771071800208 0.613627188198913 0.740116923672261 GO:0140299 molecular sensor activity 1/248 71/18639 0.0140845070422535 1.05855293048614 0.614351646021453 0.740116923672261 GO:0042379 chemokine receptor binding 1/248 72/18639 0.0138888888888889 1.04385080645161 0.619502485734221 0.740116923672261 GO:0140658 ATP-dependent chromatin remodeler activity 2/248 158/18639 0.0126582278481013 0.951357697019191 0.62405949096533 0.740116923672261 GO:0004521 RNA endonuclease activity 1/248 73/18639 0.0136986301369863 1.02955148033584 0.624584802938827 0.740116923672261 GO:0035064 methylated histone binding 1/248 74/18639 0.0135135135135135 1.01563862249346 0.629599505560349 0.740116923672261 GO:0048029 monosaccharide binding 1/248 74/18639 0.0135135135135135 1.01563862249346 0.629599505560349 0.740116923672261 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/248 243/18639 0.0123456790123457 0.927867383512545 0.630349016618623 0.740116923672261 GO:0003689 DNA clamp loader activity 2/248 160/18639 0.0125 0.939465725806452 0.630893004433179 0.740116923672261 GO:0004866 endopeptidase inhibitor activity 2/248 161/18639 0.0124223602484472 0.933630534962933 0.634273449352517 0.740116923672261 GO:0044183 protein folding chaperone 1/248 75/18639 0.0133333333333333 1.00209677419355 0.63454748954209 0.740116923672261 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0004711 ribosomal protein S6 kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0035175 histone H3S10 kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0035979 histone H2AXS139 kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0044022 histone H3S28 kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0044023 histone H4S1 kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0044024 histone H2AS1 kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0044025 histone H2BS14 kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0072354 histone H3T3 kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0072371 histone H2AS121 kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0140823 histone H2BS36 kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0140855 histone H3S57 kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0140995 histone H2A kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0140997 histone H4 kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0140998 histone H2B kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:1990244 histone H2AT120 kinase activity 3/248 245/18639 0.0122448979591837 0.920292955892034 0.635857279802907 0.740116923672261 GO:0030695 GTPase regulator activity 6/248 489/18639 0.0122699386503067 0.922174945576885 0.636250973953465 0.740116923672261 GO:0008083 growth factor activity 2/248 162/18639 0.0123456790123457 0.927867383512545 0.63762973647601 0.740116923672261 GO:0060589 nucleoside-triphosphatase regulator activity 6/248 490/18639 0.0122448979591837 0.920292955892034 0.638210486250367 0.740116923672261 GO:0004677 DNA-dependent protein kinase activity 3/248 246/18639 0.0121951219512195 0.91655192761605 0.638590000270423 0.740116923672261 GO:0140857 histone H3T45 kinase activity 3/248 246/18639 0.0121951219512195 0.91655192761605 0.638590000270423 0.740116923672261 GO:0017022 myosin binding 1/248 76/18639 0.0131578947368421 0.988911290322581 0.639429639003066 0.740116923672261 GO:0051536 iron-sulfur cluster binding 1/248 76/18639 0.0131578947368421 0.988911290322581 0.639429639003066 0.740116923672261 GO:0140034 methylation-dependent protein binding 1/248 76/18639 0.0131578947368421 0.988911290322581 0.639429639003066 0.740116923672261 GO:0035403 histone H3T6 kinase activity 3/248 247/18639 0.0121457489878543 0.912841191066998 0.64130842110518 0.74077666601129 GO:0004679 AMP-activated protein kinase activity 3/248 248/18639 0.0120967741935484 0.909160379812695 0.644012525412604 0.741145739306258 GO:0051540 metal cluster binding 1/248 77/18639 0.012987012987013 0.976068286552157 0.644246826393426 0.741145739306258 GO:0015103 inorganic anion transmembrane transporter activity 2/248 165/18639 0.0121212121212121 0.91099706744868 0.64755408328614 0.743439373509037 GO:0005254 chloride channel activity 1/248 83/18639 0.0120481927710843 0.905509133307423 0.671833172419235 0.769752177306249 GO:0004527 exonuclease activity 1/248 84/18639 0.0119047619047619 0.894729262672811 0.676219105445751 0.771653253391724 GO:0051117 ATPase binding 1/248 84/18639 0.0119047619047619 0.894729262672811 0.676219105445751 0.771653253391724 GO:0005319 lipid transporter activity 2/248 178/18639 0.0112359550561798 0.844463573758608 0.688087783096243 0.783114057782641 GO:0008081 phosphoric diester hydrolase activity 1/248 87/18639 0.0114942528735632 0.863876529477197 0.689029683349391 0.783114057782641 GO:0141003 histone H2AX kinase activity 4/248 354/18639 0.0112994350282486 0.849234554401312 0.696266671911002 0.788870163093157 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/248 181/18639 0.0110497237569061 0.830466939939405 0.696881769516923 0.788870163093157 GO:0005096 GTPase activator activity 3/248 271/18639 0.011070110701107 0.831999166765861 0.70224152156068 0.792106275194363 GO:0140996 histone H3 kinase activity 4/248 357/18639 0.0112044817927171 0.84209812957441 0.702539487893233 0.792106275194363 GO:0061135 endopeptidase regulator activity 2/248 184/18639 0.0108695652173913 0.816926718092567 0.705470391935764 0.793371460207286 GO:0035173 histone kinase activity 4/248 360/18639 0.0111111111111111 0.83508064516129 0.70871896411962 0.793371460207286 GO:0043178 alcohol binding 1/248 92/18639 0.0108695652173913 0.816926718092567 0.709268478559871 0.793371460207286 GO:0052689 carboxylic ester hydrolase activity 1/248 92/18639 0.0108695652173913 0.816926718092567 0.709268478559871 0.793371460207286 GO:0031406 carboxylic acid binding 2/248 187/18639 0.0106951871657754 0.803820941866483 0.713856111624078 0.796928124613862 GO:0042562 hormone binding 1/248 94/18639 0.0106382978723404 0.799545298558682 0.716991699078629 0.79835500032571 GO:0043177 organic acid binding 2/248 189/18639 0.0105820105820106 0.79531490015361 0.719335140128632 0.79835500032571 GO:0004867 serine-type endopeptidase inhibitor activity 1/248 95/18639 0.0105263157894737 0.791129032258065 0.720776334216322 0.79835500032571 GO:0008276 protein methyltransferase activity 1/248 95/18639 0.0105263157894737 0.791129032258065 0.720776334216322 0.79835500032571 GO:0004896 cytokine receptor activity 1/248 96/18639 0.0104166666666667 0.78288810483871 0.724510559254844 0.800923782301253 GO:0005253 monoatomic anion channel activity 1/248 103/18639 0.00970873786407767 0.729682117131225 0.749293729015757 0.826706141565143 GO:0008168 methyltransferase activity 2/248 204/18639 0.00980392156862745 0.736835863377609 0.757673193304895 0.834324956051694 GO:0008013 beta-catenin binding 1/248 106/18639 0.00943396226415094 0.709030736457699 0.759223098810834 0.834408298887247 GO:0005496 steroid binding 1/248 108/18639 0.00925925925925926 0.695900537634409 0.765624084877283 0.839089293367412 GO:0019787 ubiquitin-like protein transferase activity 5/248 479/18639 0.0104384133611691 0.784522526769479 0.767288504611709 0.839089293367412 GO:0004620 phospholipase activity 1/248 109/18639 0.00917431192660551 0.689516129032258 0.76876073303175 0.839089293367412 GO:0004518 nuclease activity 2/248 209/18639 0.00956937799043062 0.719208211143695 0.769412267239729 0.839089293367412 GO:0008094 ATP-dependent activity, acting on DNA 2/248 210/18639 0.00952380952380952 0.715783410138249 0.771700049515215 0.839965823126177 GO:1902936 phosphatidylinositol bisphosphate binding 1/248 111/18639 0.00900900900900901 0.677092414995641 0.774909152368342 0.841839885298429 GO:0016741 transferase activity, transferring one-carbon groups 2/248 215/18639 0.00930232558139535 0.69913728432108 0.78284524482007 0.848160995063031 GO:0035401 histone H3Y41 kinase activity 1/248 115/18639 0.00869565217391304 0.653541374474053 0.78672177103903 0.848160995063031 GO:0101005 deubiquitinase activity 1/248 115/18639 0.00869565217391304 0.653541374474053 0.78672177103903 0.848160995063031 GO:0140801 histone H2AXY142 kinase activity 1/248 115/18639 0.00869565217391304 0.653541374474053 0.78672177103903 0.848160995063031 GO:0015294 solute:monoatomic cation symporter activity 1/248 116/18639 0.00862068965517241 0.647907397107898 0.789577147889728 0.849621037463091 GO:0016755 aminoacyltransferase activity 5/248 496/18639 0.0100806451612903 0.757633649843913 0.792866002484266 0.851541095647238 GO:0004540 RNA nuclease activity 1/248 121/18639 0.00826446280991736 0.621134364169555 0.803292909373673 0.859048668594191 GO:0015108 chloride transmembrane transporter activity 1/248 121/18639 0.00826446280991736 0.621134364169555 0.803292909373673 0.859048668594191 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/248 122/18639 0.00819672131147541 0.616043098889477 0.805927284493844 0.859048668594191 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/248 122/18639 0.00819672131147541 0.616043098889477 0.805927284493844 0.859048668594191 GO:0016887 ATP hydrolysis activity 4/248 417/18639 0.00959232613908873 0.720932931074495 0.808787283693692 0.860476696561334 GO:0004519 endonuclease activity 1/248 127/18639 0.0078740157480315 0.591789433578867 0.818581302574406 0.867634863777367 GO:0019783 ubiquitin-like protein peptidase activity 1/248 127/18639 0.0078740157480315 0.591789433578867 0.818581302574406 0.867634863777367 GO:0016298 lipase activity 1/248 130/18639 0.00769230769230769 0.578132754342432 0.825775687565317 0.870370650208509 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/248 130/18639 0.00769230769230769 0.578132754342432 0.825775687565317 0.870370650208509 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/248 130/18639 0.00769230769230769 0.578132754342432 0.825775687565317 0.870370650208509 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/248 132/18639 0.00757575757575758 0.569373167155425 0.830413357243809 0.87363189628252 GO:0015297 antiporter activity 1/248 135/18639 0.00740740740740741 0.556720430107527 0.837140319897147 0.879074992693479 GO:0016779 nucleotidyltransferase activity 1/248 136/18639 0.00735294117647059 0.552626897533207 0.83932304799191 0.87973489845078 GO:0140101 catalytic activity, acting on a tRNA 1/248 139/18639 0.00719424460431655 0.540699698305872 0.845697950918034 0.882051104341045 GO:0140767 enzyme-substrate adaptor activity 1/248 139/18639 0.00719424460431655 0.540699698305872 0.845697950918034 0.882051104341045 GO:0042277 peptide binding 2/248 249/18639 0.00803212851405622 0.603672755538282 0.846706829356366 0.882051104341045 GO:0004713 protein tyrosine kinase activity 1/248 140/18639 0.00714285714285714 0.536837557603687 0.847766432440863 0.882051104341045 GO:0004842 ubiquitin-protein transferase activity 4/248 449/18639 0.0089086859688196 0.669552410374308 0.851517573427428 0.882964182447014 GO:0061630 ubiquitin protein ligase activity 3/248 353/18639 0.0084985835694051 0.638730238508636 0.851764034657367 0.882964182447014 GO:0045182 translation regulator activity 3/248 356/18639 0.00842696629213483 0.633347680318956 0.855720132677288 0.885443501088382 GO:0015293 symporter activity 1/248 146/18639 0.00684931506849315 0.514775740167919 0.859610018998357 0.887845384585894 GO:0008509 monoatomic anion transmembrane transporter activity 1/248 149/18639 0.00671140939597315 0.504411127949773 0.865183002229556 0.891973732717539 GO:0061659 ubiquitin-like protein ligase activity 3/248 372/18639 0.00806451612903226 0.60610691987513 0.875301516191877 0.899596078178609 GO:0008514 organic anion transmembrane transporter activity 2/248 269/18639 0.00743494423791822 0.558790022784507 0.875816308115736 0.899596078178609 GO:0140375 immune receptor activity 1/248 156/18639 0.00641025641025641 0.48177729528536 0.877344585078784 0.899596078178609 GO:0031267 small GTPase binding 2/248 283/18639 0.00706713780918728 0.531146700102588 0.893074936113539 0.91358798786013 GO:0035091 phosphatidylinositol binding 2/248 284/18639 0.00704225352112676 0.529276465243071 0.894218631227053 0.91358798786013 GO:0015291 secondary active transmembrane transporter activity 2/248 287/18639 0.00696864111498258 0.523743958637743 0.897582060715257 0.915371975432136 GO:0008201 heparin binding 1/248 172/18639 0.00581395348837209 0.436960802700675 0.901194476648511 0.917104302240089 GO:0140030 modification-dependent protein binding 1/248 173/18639 0.00578034682080925 0.434435017713966 0.902521371639098 0.917104302240089 GO:0008237 metallopeptidase activity 1/248 184/18639 0.00543478260869565 0.408463359046283 0.915996317298972 0.928609739318461 GO:1901981 phosphatidylinositol phosphate binding 1/248 185/18639 0.00540540540540541 0.406255448997385 0.917125166570706 0.928609739318461 GO:0030371 translation repressor activity 2/248 329/18639 0.0060790273556231 0.456883027747818 0.935334433540369 0.94535587389973 GO:0005216 monoatomic ion channel activity 3/248 448/18639 0.00669642857142857 0.503285210253456 0.939627060893531 0.948001633628768 GO:0005261 monoatomic cation channel activity 2/248 341/18639 0.00586510263929619 0.440805032636458 0.943428355062523 0.950143147625245 GO:0005539 glycosaminoglycan binding 1/248 242/18639 0.00413223140495868 0.310567182084777 0.961719355918178 0.966843970603355 GO:0016757 glycosyltransferase activity 1/248 267/18639 0.00374531835205993 0.281487857919536 0.972740073334193 0.976189506218356 GO:1901681 sulfur compound binding 1/248 275/18639 0.00363636363636364 0.273299120234604 0.975549003820459 0.977156194205723 GO:0030246 carbohydrate binding 1/248 280/18639 0.00357142857142857 0.268418778801843 0.977156194205723 0.977156194205723