ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0140375 immune receptor activity 50/1034 156/18639 0.320512820512821 5.77760005951495 3.83962497328063e-25 3.96633259739889e-22 GO:0038187 pattern recognition receptor activity 24/1034 48/18639 0.5 9.01305609284333 5.0023154251405e-18 2.58369591708507e-15 GO:0042605 peptide antigen binding 20/1034 45/18639 0.444444444444444 8.01160541586074 5.36296395255461e-14 1.84664725432964e-11 GO:0023023 MHC protein complex binding 18/1034 37/18639 0.486486486486487 8.76945998222594 1.38829172849149e-13 3.58526338882926e-11 GO:0023026 MHC class II protein complex binding 15/1034 27/18639 0.555555555555556 10.0145067698259 1.21782885632904e-12 2.10306885174132e-10 GO:0005126 cytokine receptor binding 48/1034 275/18639 0.174545454545455 3.14637594513803 1.22153079481587e-12 2.10306885174132e-10 GO:0003779 actin binding 63/1034 443/18639 0.142212189616253 2.56353288419472 5.267843575475e-12 7.77383201923668e-10 GO:0042277 peptide binding 44/1034 249/18639 0.176706827309237 3.18533709305306 6.95747543236235e-12 8.98384015203788e-10 GO:0030695 GTPase regulator activity 66/1034 489/18639 0.134969325153374 2.43297219684114 1.74220410737522e-11 1.97147684135024e-09 GO:0060589 nucleoside-triphosphatase regulator activity 66/1034 490/18639 0.13469387755102 2.42800694745983 1.9084964582287e-11 1.97147684135024e-09 GO:0035325 Toll-like receptor binding 10/1034 13/18639 0.769230769230769 13.8662401428359 6.49639830707103e-11 6.10070859200398e-09 GO:0030246 carbohydrate binding 42/1034 280/18639 0.15 2.703916827853 3.898389665884e-09 3.35586377071515e-07 GO:0004896 cytokine receptor activity 22/1034 96/18639 0.229166666666667 4.13098404255319 9.81822136127235e-09 7.80170974322641e-07 GO:0019955 cytokine binding 27/1034 144/18639 0.1875 3.37989603481625 2.19246026321241e-08 1.61772246564173e-06 GO:0004875 complement receptor activity 8/1034 12/18639 0.666666666666667 12.0174081237911 3.54115315733817e-08 2.43867414102022e-06 GO:0005085 guanyl-nucleotide exchange factor activity 35/1034 230/18639 0.152173913043478 2.74310402825666 5.32065994062091e-08 3.43515107416337e-06 GO:0032396 inhibitory MHC class I receptor activity 8/1034 13/18639 0.615384615384615 11.0929921142687 8.75739744728892e-08 5.3214068017938e-06 GO:0001540 amyloid-beta binding 19/1034 83/18639 0.228915662650602 4.12645941600056 1.00936749249082e-07 5.79264788746121e-06 GO:0032393 MHC class I receptor activity 9/1034 18/18639 0.5 9.01305609284333 1.48343947346581e-07 8.06522618994835e-06 GO:0032395 MHC class II receptor activity 7/1034 10/18639 0.7 12.6182785299807 1.64120635200732e-07 8.4768308081178e-06 GO:0005125 cytokine activity 34/1034 234/18639 0.145299145299145 2.61917869364678 2.5518521318073e-07 1.25526821531283e-05 GO:0042379 chemokine receptor binding 17/1034 72/18639 0.236111111111111 4.25616537717602 2.9340253957173e-07 1.37765828807999e-05 GO:0003823 antigen binding 28/1034 174/18639 0.160919540229885 2.90075368505302 3.51070693872407e-07 1.57676533378346e-05 GO:0005096 GTPase activator activity 37/1034 271/18639 0.136531365313653 2.46112970800888 3.78130218791734e-07 1.62753548338275e-05 GO:0017124 SH3 domain binding 20/1034 115/18639 0.173913043478261 3.13497603229333 4.8373351372151e-06 0.000193575625288321 GO:0051015 actin filament binding 29/1034 209/18639 0.138755980861244 2.50123087743978 4.87218417957052e-06 0.000193575625288321 GO:0001784 phosphotyrosine residue binding 12/1034 47/18639 0.25531914893617 4.60241162187744 6.83931948341544e-06 0.000261667297272894 GO:0140313 molecular sequestering activity 13/1034 55/18639 0.236363636363636 4.26071742570775 7.17860026864166e-06 0.000264839074196673 GO:0019956 chemokine binding 10/1034 33/18639 0.303030303030303 5.46245823808686 7.58289143988429e-06 0.000270107822668982 GO:0001618 virus receptor activity 16/1034 81/18639 0.197530864197531 3.56071351816033 7.95998493508048e-06 0.000274088814597938 GO:0005543 phospholipid binding 52/1034 497/18639 0.104627766599598 1.88603185846219 8.25329609057019e-06 0.000275021124566419 GO:0140272 exogenous protein binding 16/1034 82/18639 0.195121951219512 3.51729018257301 9.38673925536511e-06 0.000303015676587255 GO:0042287 MHC protein binding 11/1034 41/18639 0.268292682926829 4.83627400103788 9.84700755075352e-06 0.000308241175755406 GO:0019864 IgG binding 6/1034 11/18639 0.545454545454545 9.83242482855636 1.04300813077525e-05 0.000316890411497303 GO:0048029 monosaccharide binding 15/1034 74/18639 0.202702702702703 3.65394165926081 1.0937880906433e-05 0.000322823742181294 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 7/1034 16/18639 0.4375 7.88642408123791 1.16456143650328e-05 0.000328961228136722 GO:1901981 phosphatidylinositol phosphate binding 26/1034 185/18639 0.140540540540541 2.53339955042083 1.17827351801149e-05 0.000328961228136722 GO:0033218 amide binding 31/1034 247/18639 0.125506072874494 2.26238654962059 1.84212910333661e-05 0.000500768253617557 GO:0061134 peptidase regulator activity 29/1034 226/18639 0.128318584070796 2.31308519196864 2.23523977326726e-05 0.000592051970714123 GO:0004715 non-membrane spanning protein tyrosine kinase activity 11/1034 45/18639 0.244444444444444 4.4063829787234 2.5793655637597e-05 0.000649874299357017 GO:0008009 chemokine activity 11/1034 45/18639 0.244444444444444 4.4063829787234 2.5793655637597e-05 0.000649874299357017 GO:0005178 integrin binding 23/1034 161/18639 0.142857142857143 2.57515888366952 2.83600281619288e-05 0.000697521645030298 GO:0038024 cargo receptor activity 13/1034 65/18639 0.2 3.60522243713733 4.85030668663061e-05 0.00116520158309056 GO:0019865 immunoglobulin binding 8/1034 26/18639 0.307692307692308 5.54649605713436 5.56156413875863e-05 0.00128909377041282 GO:0003725 double-stranded RNA binding 14/1034 75/18639 0.186666666666667 3.36487427466151 5.61560693790675e-05 0.00128909377041282 GO:0045309 protein phosphorylated amino acid binding 12/1034 59/18639 0.203389830508475 3.66632790217356 7.91816524917016e-05 0.00177814450052017 GO:0061135 endopeptidase regulator activity 24/1034 184/18639 0.130434782608696 2.35123202422 8.53642847544585e-05 0.00186164349951909 GO:0140297 DNA-binding transcription factor binding 48/1034 488/18639 0.0983606557377049 1.77306021498557 8.65042477995318e-05 0.00186164349951909 GO:0031267 small GTPase binding 32/1034 283/18639 0.113074204946996 2.03828830368188 0.000105934845208395 0.00223327949184229 GO:0035091 phosphatidylinositol binding 32/1034 284/18639 0.112676056338028 2.03111123219005 0.000113200993696989 0.0023387325297798 GO:0033691 sialic acid binding 7/1034 22/18639 0.318181818181818 5.73558114999121 0.000129411718223676 0.00262122166519721 GO:0019207 kinase regulator activity 32/1034 287/18639 0.111498257839721 2.00988010432743 0.000137765701272034 0.00273676864257714 GO:0051020 GTPase binding 34/1034 315/18639 0.107936507936508 1.94567560099475 0.000162355235273692 0.00316439543467403 GO:0042608 T cell receptor binding 5/1034 11/18639 0.454545454545455 8.1936873571303 0.000181477921558027 0.00340848532671713 GO:0050786 RAGE receptor binding 5/1034 11/18639 0.454545454545455 8.1936873571303 0.000181477921558027 0.00340848532671713 GO:0030169 low-density lipoprotein particle binding 6/1034 17/18639 0.352941176470588 6.36215724200706 0.000209402915753089 0.00386273592808823 GO:0019957 C-C chemokine binding 7/1034 24/18639 0.291666666666667 5.25761605415861 0.000238210381773603 0.00431704077845845 GO:0070851 growth factor receptor binding 19/1034 139/18639 0.136690647482014 2.46400094624494 0.000246011864137909 0.00438155613197345 GO:0016504 peptidase activator activity 11/1034 57/18639 0.192982456140351 3.47872340425532 0.000254672505430179 0.00445892708659958 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 9/1034 40/18639 0.225 4.0558752417795 0.00027616685682656 0.00475467271836393 GO:0030228 lipoprotein particle receptor activity 6/1034 18/18639 0.333333333333333 6.00870406189555 0.000299420032328102 0.0050705064490972 GO:0001530 lipopolysaccharide binding 9/1034 41/18639 0.219512195121951 3.95695145539463 0.000336614393851216 0.0055194074420366 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 9/1034 41/18639 0.219512195121951 3.95695145539463 0.000336614393851216 0.0055194074420366 GO:0140311 protein sequestering activity 8/1034 33/18639 0.242424242424242 4.36996659046949 0.000349563291466973 0.00564217000133411 GO:0001637 G protein-coupled chemoattractant receptor activity 7/1034 26/18639 0.269230769230769 4.85318404999256 0.000410716529957666 0.00642833599161014 GO:0004950 chemokine receptor activity 7/1034 26/18639 0.269230769230769 4.85318404999256 0.000410716529957666 0.00642833599161014 GO:0019887 protein kinase regulator activity 28/1034 255/18639 0.109803921568627 1.97933780862442 0.000450247411145257 0.00694187426437389 GO:0004857 enzyme inhibitor activity 40/1034 416/18639 0.0961538461538462 1.73328001785449 0.000515238820236851 0.0078270838427157 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 35/1034 349/18639 0.100286532951289 1.8077762936935 0.000528605991389906 0.00791376795805468 GO:0005154 epidermal growth factor receptor binding 8/1034 35/18639 0.228571428571429 4.12025421387123 0.000536909624463977 0.00792325202958983 GO:0042288 MHC class I protein binding 6/1034 20/18639 0.3 5.407833655706 0.000568169646758232 0.00826646824086272 GO:0051219 phosphoprotein binding 14/1034 93/18639 0.150537634408602 2.71360828601735 0.000587634863579223 0.00843092797329635 GO:0019763 immunoglobulin receptor activity 5/1034 14/18639 0.357142857142857 6.4378972091738 0.000683708253558845 0.00967494008118201 GO:0043394 proteoglycan binding 8/1034 37/18639 0.216216216216216 3.8975377698782 0.0007981456320896 0.0111416815938994 GO:0003924 GTPase activity 33/1034 331/18639 0.0996978851963746 1.79716526322556 0.000832371260341435 0.0113002784785356 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 7/1034 29/18639 0.241379310344828 4.35113052757954 0.000842324726860832 0.0113002784785356 GO:0051861 glycolipid binding 7/1034 29/18639 0.241379310344828 4.35113052757954 0.000842324726860832 0.0113002784785356 GO:0005041 low-density lipoprotein particle receptor activity 5/1034 15/18639 0.333333333333333 6.00870406189555 0.000978957341671162 0.0129649094095681 GO:0061133 endopeptidase activator activity 6/1034 22/18639 0.272727272727273 4.91621241427818 0.000994237697257511 0.01300060178819 GO:0019903 protein phosphatase binding 18/1034 144/18639 0.125 2.25326402321083 0.0010411661019193 0.013444057291033 GO:0001664 G protein-coupled receptor binding 30/1034 297/18639 0.101010101010101 1.82081941269562 0.00114128621626586 0.0145549217457115 GO:0016493 C-C chemokine receptor activity 6/1034 23/18639 0.260869565217391 4.70246404844 0.00128261595012366 0.0161578326399725 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 5/1034 16/18639 0.3125 5.63316005802708 0.00135932488101455 0.0166731119954255 GO:0061791 GTPase motor activity 8/1034 40/18639 0.2 3.60522243713733 0.0013719404836507 0.0166731119954255 GO:1990606 membrane scission GTPase motor activity 8/1034 40/18639 0.2 3.60522243713733 0.0013719404836507 0.0166731119954255 GO:0002020 protease binding 17/1034 136/18639 0.125 2.25326402321083 0.00141717163670357 0.0170225383804045 GO:0005131 growth hormone receptor binding 4/1034 10/18639 0.4 7.21044487427466 0.00150992935163948 0.0174470720034878 GO:0016175 superoxide-generating NAD(P)H oxidase activity 4/1034 10/18639 0.4 7.21044487427466 0.00150992935163948 0.0174470720034878 GO:0071723 lipopeptide binding 4/1034 10/18639 0.4 7.21044487427466 0.00150992935163948 0.0174470720034878 GO:0032813 tumor necrosis factor receptor superfamily binding 9/1034 50/18639 0.18 3.2447001934236 0.00153857426030847 0.0174470720034878 GO:0048020 CCR chemokine receptor binding 9/1034 50/18639 0.18 3.2447001934236 0.00153857426030847 0.0174470720034878 GO:0071813 lipoprotein particle binding 7/1034 32/18639 0.21875 3.94321204061896 0.0015707431716596 0.0174470720034878 GO:0071814 protein-lipid complex binding 7/1034 32/18639 0.21875 3.94321204061896 0.0015707431716596 0.0174470720034878 GO:0042169 SH2 domain binding 8/1034 41/18639 0.195121951219512 3.51729018257301 0.00162292862663239 0.0178349496948007 GO:0015026 coreceptor activity 10/1034 61/18639 0.163934426229508 2.95510035830929 0.00180229779249037 0.0193788589928842 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 5/1034 17/18639 0.294117647058824 5.30179770167255 0.00183845903320683 0.0193788589928842 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 5/1034 17/18639 0.294117647058824 5.30179770167255 0.00183845903320683 0.0193788589928842 GO:0045236 CXCR chemokine receptor binding 5/1034 17/18639 0.294117647058824 5.30179770167255 0.00183845903320683 0.0193788589928842 GO:0042056 chemoattractant activity 8/1034 42/18639 0.19047619047619 3.43354517822603 0.00190889376770931 0.0199180531519567 GO:0019902 phosphatase binding 21/1034 190/18639 0.110526315789474 1.99235976789168 0.00203661248634106 0.0210382069839032 GO:0001851 complement component C3b binding 4/1034 11/18639 0.363636363636364 6.55494988570424 0.00226904445454317 0.0230823149382372 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 7/1034 34/18639 0.205882352941176 3.71125839117078 0.00227918308199438 0.0230823149382372 GO:0004126 cytidine deaminase activity 4/1034 12/18639 0.333333333333333 6.00870406189555 0.00325511370103964 0.0320241186016566 GO:0035259 nuclear glucocorticoid receptor binding 4/1034 12/18639 0.333333333333333 6.00870406189555 0.00325511370103964 0.0320241186016566 GO:0035497 cAMP response element binding 4/1034 12/18639 0.333333333333333 6.00870406189555 0.00325511370103964 0.0320241186016566 GO:0004866 endopeptidase inhibitor activity 18/1034 161/18639 0.111801242236025 2.01534173504571 0.00363199149837299 0.035394785073767 GO:0046625 sphingolipid binding 6/1034 28/18639 0.214285714285714 3.86273832550428 0.00377623934507842 0.0361190300320927 GO:0051019 mitogen-activated protein kinase binding 6/1034 28/18639 0.214285714285714 3.86273832550428 0.00377623934507842 0.0361190300320927 GO:0005525 GTP binding 34/1034 378/18639 0.0899470899470899 1.62139633416229 0.00387150541534225 0.0366905054499866 GO:0001614 purinergic nucleotide receptor activity 5/1034 20/18639 0.25 4.50652804642166 0.00400981525536447 0.0369833853463526 GO:0016502 nucleotide receptor activity 5/1034 20/18639 0.25 4.50652804642166 0.00400981525536447 0.0369833853463526 GO:0016505 peptidase activator activity involved in apoptotic process 5/1034 20/18639 0.25 4.50652804642166 0.00400981525536447 0.0369833853463526 GO:0046332 SMAD binding 11/1034 79/18639 0.139240506329114 2.50996498788042 0.00411310745977251 0.0376003540349115 GO:0035401 histone H3Y41 kinase activity 14/1034 115/18639 0.121739130434783 2.19448322260533 0.00457753273234926 0.0411181853262329 GO:0140801 histone H2AXY142 kinase activity 14/1034 115/18639 0.121739130434783 2.19448322260533 0.00457753273234926 0.0411181853262329 GO:0001846 opsonin binding 5/1034 21/18639 0.238095238095238 4.29193147278254 0.00502589000184963 0.0447564169992299 GO:0035591 signaling adaptor activity 15/1034 129/18639 0.116279069767442 2.09605955647519 0.00525519249655537 0.0457484934224184 GO:0019001 guanyl nucleotide binding 35/1034 400/18639 0.0875 1.57728481624758 0.00527015558302787 0.0457484934224184 GO:0032561 guanyl ribonucleotide binding 35/1034 400/18639 0.0875 1.57728481624758 0.00527015558302787 0.0457484934224184 GO:0098531 ligand-modulated transcription factor activity 9/1034 60/18639 0.15 2.703916827853 0.0055393306450497 0.0476844046361362 GO:0019992 diacylglycerol binding 4/1034 14/18639 0.285714285714286 5.15031776733904 0.00602255705558985 0.0511295890217339 GO:0030414 peptidase inhibitor activity 18/1034 169/18639 0.106508875739645 1.9199409428542 0.00603853810324447 0.0511295890217339 GO:0005164 tumor necrosis factor receptor binding 6/1034 31/18639 0.193548387096774 3.48892493916516 0.00640590423121726 0.053799179437784 GO:0004860 protein kinase inhibitor activity 11/1034 84/18639 0.130952380952381 2.3605623100304 0.00658231203615692 0.0548349059141137 GO:0004953 icosanoid receptor activity 4/1034 15/18639 0.266666666666667 4.80696324951644 0.00785659331519665 0.0644115944015725 GO:0050700 CARD domain binding 4/1034 15/18639 0.266666666666667 4.80696324951644 0.00785659331519665 0.0644115944015725 GO:0019209 kinase activator activity 16/1034 148/18639 0.108108108108108 1.9487688849391 0.00809616140448243 0.0658530293766169 GO:0044325 transmembrane transporter binding 15/1034 136/18639 0.110294117647059 1.9881741381272 0.00849935153370992 0.0685924229243933 GO:0019239 deaminase activity 6/1034 33/18639 0.181818181818182 3.27747494285212 0.00877108579833312 0.0696963971513701 GO:0030296 protein tyrosine kinase activator activity 6/1034 33/18639 0.181818181818182 3.27747494285212 0.00877108579833312 0.0696963971513701 GO:0042625 ATPase-coupled ion transmembrane transporter activity 5/1034 24/18639 0.208333333333333 3.75544003868472 0.0091466677599297 0.0710414120000555 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 5/1034 24/18639 0.208333333333333 3.75544003868472 0.0091466677599297 0.0710414120000555 GO:0046961 proton-transporting ATPase activity, rotational mechanism 5/1034 24/18639 0.208333333333333 3.75544003868472 0.0091466677599297 0.0710414120000555 GO:0001216 DNA-binding transcription activator activity 40/1034 491/18639 0.0814663951120163 1.46852237765268 0.00980852000655766 0.07561344154309 GO:0005149 interleukin-1 receptor binding 4/1034 16/18639 0.25 4.50652804642166 0.010022349459924 0.0766895332748262 GO:0030295 protein kinase activator activity 15/1034 139/18639 0.107913669064748 1.94526390493021 0.0103036180459647 0.0782620400108938 GO:0001848 complement binding 5/1034 25/18639 0.2 3.60522243713733 0.0109217807022555 0.0806516395587677 GO:0005537 D-mannose binding 5/1034 25/18639 0.2 3.60522243713733 0.0109217807022555 0.0806516395587677 GO:0120020 cholesterol transfer activity 5/1034 25/18639 0.2 3.60522243713733 0.0109217807022555 0.0806516395587677 GO:0019210 kinase inhibitor activity 11/1034 90/18639 0.122222222222222 2.2031914893617 0.0109305223022531 0.0806516395587677 GO:0008429 phosphatidylethanolamine binding 4/1034 17/18639 0.235294117647059 4.24143816133804 0.0125404695912216 0.0896622382295354 GO:0046965 nuclear retinoid X receptor binding 4/1034 17/18639 0.235294117647059 4.24143816133804 0.0125404695912216 0.0896622382295354 GO:0070492 oligosaccharide binding 4/1034 17/18639 0.235294117647059 4.24143816133804 0.0125404695912216 0.0896622382295354 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 39/1034 484/18639 0.0805785123966942 1.45251730421855 0.012601235123709 0.0896622382295354 GO:0044389 ubiquitin-like protein ligase binding 28/1034 322/18639 0.0869565217391304 1.56748801614667 0.0126373466329109 0.0896622382295354 GO:0048306 calcium-dependent protein binding 10/1034 80/18639 0.125 2.25326402321083 0.0128075496704102 0.0896622382295354 GO:0043548 phosphatidylinositol 3-kinase binding 5/1034 26/18639 0.192307692307692 3.46656003570897 0.0129181890054528 0.0896622382295354 GO:0070412 R-SMAD binding 5/1034 26/18639 0.192307692307692 3.46656003570897 0.0129181890054528 0.0896622382295354 GO:1990782 protein tyrosine kinase binding 13/1034 117/18639 0.111111111111111 2.00290135396518 0.0129328881860608 0.0896622382295354 GO:0004869 cysteine-type endopeptidase inhibitor activity 6/1034 36/18639 0.166666666666667 3.00435203094778 0.0134013894462637 0.0922909019866026 GO:0008028 monocarboxylic acid transmembrane transporter activity 9/1034 70/18639 0.128571428571429 2.31764299530257 0.0149262700045024 0.0995490187920029 GO:0004683 calcium/calmodulin-dependent protein kinase activity 5/1034 27/18639 0.185185185185185 3.33816892327531 0.0151471441679954 0.0995490187920029 GO:0005044 scavenger receptor activity 5/1034 27/18639 0.185185185185185 3.33816892327531 0.0151471441679954 0.0995490187920029 GO:0004955 prostaglandin receptor activity 3/1034 10/18639 0.3 5.407833655706 0.015226277801681 0.0995490187920029 GO:0005522 profilin binding 3/1034 10/18639 0.3 5.407833655706 0.015226277801681 0.0995490187920029 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 3/1034 10/18639 0.3 5.407833655706 0.015226277801681 0.0995490187920029 GO:0043208 glycosphingolipid binding 3/1034 10/18639 0.3 5.407833655706 0.015226277801681 0.0995490187920029 GO:0043422 protein kinase B binding 3/1034 10/18639 0.3 5.407833655706 0.015226277801681 0.0995490187920029 GO:0016854 racemase and epimerase activity 4/1034 18/18639 0.222222222222222 4.00580270793037 0.0154290617285798 0.100240382173729 GO:0004879 nuclear receptor activity 8/1034 59/18639 0.135593220338983 2.44421860144904 0.0156899641783392 0.101298331226402 GO:0034987 immunoglobulin receptor binding 4/1034 19/18639 0.210526315789474 3.79497098646035 0.018703637162011 0.118532866186241 GO:0042834 peptidoglycan binding 4/1034 19/18639 0.210526315789474 3.79497098646035 0.018703637162011 0.118532866186241 GO:0097001 ceramide binding 4/1034 19/18639 0.210526315789474 3.79497098646035 0.018703637162011 0.118532866186241 GO:0004954 prostanoid receptor activity 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.121333644660725 GO:0005225 volume-sensitive anion channel activity 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.121333644660725 GO:0005536 D-glucose binding 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.121333644660725 GO:0008199 ferric iron binding 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.121333644660725 GO:0016176 superoxide-generating NADPH oxidase activator activity 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.121333644660725 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.121333644660725 GO:0034713 type I transforming growth factor beta receptor binding 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.121333644660725 GO:0140031 phosphorylation-dependent protein binding 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.121333644660725 GO:0003785 actin monomer binding 5/1034 29/18639 0.172413793103448 3.10795037684253 0.0203435532538866 0.122179595995726 GO:0071949 FAD binding 6/1034 40/18639 0.15 2.703916827853 0.0219136437697953 0.130848520313286 GO:0030742 GTP-dependent protein binding 4/1034 20/18639 0.2 3.60522243713733 0.0223770926386726 0.132847912044533 GO:0019003 GDP binding 9/1034 75/18639 0.12 2.1631334622824 0.0225954986718396 0.133378000731488 GO:0001965 G-protein alpha-subunit binding 5/1034 30/18639 0.166666666666667 3.00435203094778 0.0233291953054671 0.136152874296878 GO:0001968 fibronectin binding 5/1034 30/18639 0.166666666666667 3.00435203094778 0.0233291953054671 0.136152874296878 GO:0004713 protein tyrosine kinase activity 14/1034 140/18639 0.1 1.80261121856867 0.0236145156776142 0.136707591333514 GO:0004197 cysteine-type endopeptidase activity 10/1034 88/18639 0.113636363636364 2.04842183928257 0.0236889243453041 0.136707591333514 GO:0097677 STAT family protein binding 3/1034 12/18639 0.25 4.50652804642166 0.025695282508797 0.147462371286596 GO:0035198 miRNA binding 6/1034 42/18639 0.142857142857143 2.57515888366952 0.0272916813824929 0.155758601481299 GO:0005539 glycosaminoglycan binding 21/1034 242/18639 0.0867768595041322 1.56424940454306 0.0285345568515651 0.161957127624543 GO:0003925 G protein activity 7/1034 54/18639 0.12962962962963 2.33671824629271 0.0288643120979032 0.162933521295814 GO:0120015 sterol transfer activity 5/1034 32/18639 0.15625 2.81658002901354 0.0301136676412872 0.169062058007878 GO:0033293 monocarboxylic acid binding 9/1034 79/18639 0.113924050632911 2.05360771735671 0.0304960786765111 0.170283509582897 GO:0005172 vascular endothelial growth factor receptor binding 3/1034 13/18639 0.230769230769231 4.15987204285077 0.0320547157563618 0.17427642829643 GO:0008035 high-density lipoprotein particle binding 3/1034 13/18639 0.230769230769231 4.15987204285077 0.0320547157563618 0.17427642829643 GO:0043560 insulin receptor substrate binding 3/1034 13/18639 0.230769230769231 4.15987204285077 0.0320547157563618 0.17427642829643 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 3/1034 13/18639 0.230769230769231 4.15987204285077 0.0320547157563618 0.17427642829643 GO:0071714 icosanoid transmembrane transporter activity 3/1034 13/18639 0.230769230769231 4.15987204285077 0.0320547157563618 0.17427642829643 GO:0043177 organic acid binding 17/1034 189/18639 0.0899470899470899 1.62139633416229 0.0340387974825994 0.184094648165053 GO:0170055 lipid transmembrane transporter activity 7/1034 56/18639 0.125 2.25326402321083 0.0343966224914546 0.185060994967045 GO:0004602 glutathione peroxidase activity 4/1034 23/18639 0.173913043478261 3.13497603229333 0.0358810750587931 0.192047412102245 GO:0005319 lipid transporter activity 16/1034 178/18639 0.0898876404494382 1.62032469084824 0.0390932950789059 0.205312134265451 GO:0005161 platelet-derived growth factor receptor binding 3/1034 14/18639 0.214285714285714 3.86273832550428 0.0391543954020269 0.205312134265451 GO:0005545 1-phosphatidylinositol binding 3/1034 14/18639 0.214285714285714 3.86273832550428 0.0391543954020269 0.205312134265451 GO:0008191 metalloendopeptidase inhibitor activity 3/1034 14/18639 0.214285714285714 3.86273832550428 0.0391543954020269 0.205312134265451 GO:0097110 scaffold protein binding 8/1034 70/18639 0.114285714285714 2.06012710693562 0.039408554164563 0.205601194201988 GO:0005516 calmodulin binding 18/1034 207/18639 0.0869565217391304 1.56748801614667 0.039665015769032 0.20589930296186 GO:0061980 regulatory RNA binding 7/1034 58/18639 0.120689655172414 2.17556526378977 0.0405903679937658 0.2096492506878 GO:0001091 RNA polymerase II general transcription initiation factor binding 4/1034 24/18639 0.166666666666667 3.00435203094778 0.0412279565185658 0.210485649694606 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 4/1034 24/18639 0.166666666666667 3.00435203094778 0.0412279565185658 0.210485649694606 GO:0140996 histone H3 kinase activity 28/1034 357/18639 0.0784313725490196 1.41381272044601 0.0413635884685432 0.210485649694606 GO:0042626 ATPase-coupled transmembrane transporter activity 10/1034 98/18639 0.102040816326531 1.83939920262109 0.0451067812899317 0.227576198160997 GO:0035173 histone kinase activity 28/1034 360/18639 0.0777777777777778 1.40203094777563 0.0451627498770613 0.227576198160997 GO:0005200 structural constituent of cytoskeleton 11/1034 112/18639 0.0982142857142857 1.7704217325228 0.0464979389517227 0.232304210350933 GO:0120283 protein serine/threonine kinase binding 3/1034 15/18639 0.2 3.60522243713733 0.0469788459237345 0.232304210350933 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 4/1034 25/18639 0.16 2.88417794970986 0.0470005614359583 0.232304210350933 GO:0042974 nuclear retinoic acid receptor binding 4/1034 25/18639 0.16 2.88417794970986 0.0470005614359583 0.232304210350933 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 9/1034 86/18639 0.104651162790698 1.88645360082767 0.0486048472429395 0.237956432236761 GO:0016209 antioxidant activity 9/1034 86/18639 0.104651162790698 1.88645360082767 0.0486048472429395 0.237956432236761 GO:0141108 transporter regulator activity 15/1034 170/18639 0.0882352941176471 1.59053931050176 0.0511122340656029 0.249051593347961 GO:0016763 pentosyltransferase activity 6/1034 49/18639 0.122448979591837 2.2072790431453 0.0526717854162579 0.253239028503652 GO:0004435 phosphatidylinositol phospholipase C activity 4/1034 26/18639 0.153846153846154 2.77324802856718 0.0531973564233229 0.253239028503652 GO:0005160 transforming growth factor beta receptor binding 4/1034 26/18639 0.153846153846154 2.77324802856718 0.0531973564233229 0.253239028503652 GO:0008157 protein phosphatase 1 binding 4/1034 26/18639 0.153846153846154 2.77324802856718 0.0531973564233229 0.253239028503652 GO:0030247 polysaccharide binding 4/1034 26/18639 0.153846153846154 2.77324802856718 0.0531973564233229 0.253239028503652 GO:0005521 lamin binding 3/1034 16/18639 0.1875 3.37989603481625 0.0555072681846138 0.261821954496375 GO:0031435 mitogen-activated protein kinase kinase kinase binding 3/1034 16/18639 0.1875 3.37989603481625 0.0555072681846138 0.261821954496375 GO:0031406 carboxylic acid binding 16/1034 187/18639 0.0855614973262032 1.54234114957747 0.0566183447144696 0.265848864045668 GO:0043531 ADP binding 5/1034 38/18639 0.131578947368421 2.37185686653772 0.0573255934238217 0.267951755686913 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 9/1034 89/18639 0.101123595505618 1.82286527720427 0.0581686918790738 0.269454074937593 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 9/1034 89/18639 0.101123595505618 1.82286527720427 0.0581686918790738 0.269454074937593 GO:0141003 histone H2AX kinase activity 27/1034 354/18639 0.076271186440678 1.37487296331508 0.0588500814306 0.271393455883079 GO:0001217 DNA-binding transcription repressor activity 22/1034 278/18639 0.079136690647482 1.42652686361549 0.059860002987407 0.274823924826629 GO:0140793 histone H2AXY142 phosphatase activity 9/1034 90/18639 0.1 1.80261121856867 0.0616073166841984 0.281594505021137 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 5/1034 39/18639 0.128205128205128 2.31104002380598 0.0628860926527608 0.286173276256837 GO:0004029 aldehyde dehydrogenase (NAD+) activity 3/1034 17/18639 0.176470588235294 3.18107862100353 0.0647144393117693 0.288146619866628 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 3/1034 17/18639 0.176470588235294 3.18107862100353 0.0647144393117693 0.288146619866628 GO:0005092 GDP-dissociation inhibitor activity 3/1034 17/18639 0.176470588235294 3.18107862100353 0.0647144393117693 0.288146619866628 GO:0036041 long-chain fatty acid binding 3/1034 17/18639 0.176470588235294 3.18107862100353 0.0647144393117693 0.288146619866628 GO:0045125 bioactive lipid receptor activity 3/1034 17/18639 0.176470588235294 3.18107862100353 0.0647144393117693 0.288146619866628 GO:0005080 protein kinase C binding 6/1034 52/18639 0.115384615384615 2.07993602142538 0.0668422647902145 0.295099856199908 GO:0046875 ephrin receptor binding 4/1034 28/18639 0.142857142857143 2.57515888366952 0.0668474020820702 0.295099856199908 GO:0015036 disulfide oxidoreductase activity 5/1034 40/18639 0.125 2.25326402321083 0.0687392996360416 0.302160410740557 GO:0140296 general transcription initiation factor binding 6/1034 53/18639 0.113207547169811 2.04069194554943 0.0720130211620902 0.315209537544234 GO:0004629 phospholipase C activity 4/1034 29/18639 0.137931034482759 2.48636030147402 0.0742880178945795 0.319636410032135 GO:0043236 laminin binding 4/1034 29/18639 0.137931034482759 2.48636030147402 0.0742880178945795 0.319636410032135 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 3/1034 18/18639 0.166666666666667 3.00435203094778 0.0745715148284071 0.319636410032135 GO:0004706 JUN kinase kinase kinase activity 3/1034 18/18639 0.166666666666667 3.00435203094778 0.0745715148284071 0.319636410032135 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 3/1034 18/18639 0.166666666666667 3.00435203094778 0.0745715148284071 0.319636410032135 GO:0017080 sodium channel regulator activity 5/1034 41/18639 0.121951219512195 2.19830636410813 0.0748830497000379 0.319645414628674 GO:0050840 extracellular matrix binding 7/1034 67/18639 0.104477611940299 1.88332515372846 0.0771167907624565 0.325044828936392 GO:0031625 ubiquitin protein ligase binding 23/1034 302/18639 0.076158940397351 1.37284960354567 0.0773329267025987 0.325044828936392 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 6/1034 54/18639 0.111111111111111 2.00290135396518 0.0774066097951137 0.325044828936392 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 6/1034 54/18639 0.111111111111111 2.00290135396518 0.0774066097951137 0.325044828936392 GO:0030971 receptor tyrosine kinase binding 8/1034 81/18639 0.0987654320987654 1.78035675908016 0.079722438970429 0.333414086868232 GO:0030145 manganese ion binding 7/1034 68/18639 0.102941176470588 1.85562919558539 0.0820704227478613 0.340715081796545 GO:0035925 mRNA 3'-UTR AU-rich region binding 4/1034 30/18639 0.133333333333333 2.40348162475822 0.082127836754443 0.340715081796545 GO:0016247 channel regulator activity 14/1034 168/18639 0.0833333333333333 1.50217601547389 0.0841255512497662 0.345879072335648 GO:0005229 intracellularly calcium-gated chloride channel activity 3/1034 19/18639 0.157894736842105 2.84622823984526 0.0850467418908564 0.345879072335648 GO:0015245 fatty acid transmembrane transporter activity 3/1034 19/18639 0.157894736842105 2.84622823984526 0.0850467418908564 0.345879072335648 GO:0070003 threonine-type peptidase activity 3/1034 19/18639 0.157894736842105 2.84622823984526 0.0850467418908564 0.345879072335648 GO:0141147 intracellularly calcium-gated channel activity 3/1034 19/18639 0.157894736842105 2.84622823984526 0.0850467418908564 0.345879072335648 GO:1902936 phosphatidylinositol bisphosphate binding 10/1034 111/18639 0.0900900900900901 1.62397407078258 0.088546628196956 0.358700654617473 GO:0004725 protein tyrosine phosphatase activity 9/1034 98/18639 0.0918367346938776 1.65545928235898 0.0937251645608916 0.377534535672537 GO:0004601 peroxidase activity 6/1034 57/18639 0.105263157894737 1.89748549323017 0.0949094479458169 0.377534535672537 GO:0001046 core promoter sequence-specific DNA binding 5/1034 44/18639 0.113636363636364 2.04842183928257 0.0950232132380056 0.377534535672537 GO:0001223 transcription coactivator binding 5/1034 44/18639 0.113636363636364 2.04842183928257 0.0950232132380056 0.377534535672537 GO:0030547 signaling receptor inhibitor activity 5/1034 44/18639 0.113636363636364 2.04842183928257 0.0950232132380056 0.377534535672537 GO:0016004 phospholipase activator activity 3/1034 20/18639 0.15 2.703916827853 0.0961060917588888 0.380373918723878 GO:0043425 bHLH transcription factor binding 4/1034 32/18639 0.125 2.25326402321083 0.0989627349699707 0.388701540775588 GO:0051059 NF-kappaB binding 4/1034 32/18639 0.125 2.25326402321083 0.0989627349699707 0.388701540775588 GO:0046915 transition metal ion transmembrane transporter activity 5/1034 45/18639 0.111111111111111 2.00290135396518 0.102290844602534 0.38950208184215 GO:0001094 TFIID-class transcription factor complex binding 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.38950208184215 GO:0004382 GDP phosphatase activity 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.38950208184215 GO:0005031 tumor necrosis factor receptor activity 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.38950208184215 GO:0005345 purine nucleobase transmembrane transporter activity 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.38950208184215 GO:0005381 iron ion transmembrane transporter activity 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.38950208184215 GO:0005528 FK506 binding 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.38950208184215 GO:0016303 1-phosphatidylinositol-3-kinase activity 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.38950208184215 GO:0050308 sugar-phosphatase activity 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.38950208184215 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.38950208184215 GO:0050660 flavin adenine dinucleotide binding 8/1034 86/18639 0.0930232558139535 1.67684764518015 0.104005552783849 0.392108525641299 GO:0001221 transcription coregulator binding 10/1034 115/18639 0.0869565217391304 1.56748801614667 0.105709678702432 0.39358624666643 GO:0015459 potassium channel regulator activity 6/1034 59/18639 0.101694915254237 1.83316395108678 0.107656432810773 0.39358624666643 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 6/1034 59/18639 0.101694915254237 1.83316395108678 0.107656432810773 0.39358624666643 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/1034 21/18639 0.142857142857143 2.57515888366952 0.107713818959834 0.39358624666643 GO:0008373 sialyltransferase activity 3/1034 21/18639 0.142857142857143 2.57515888366952 0.107713818959834 0.39358624666643 GO:0009931 calcium-dependent protein serine/threonine kinase activity 3/1034 21/18639 0.142857142857143 2.57515888366952 0.107713818959834 0.39358624666643 GO:0019200 carbohydrate kinase activity 3/1034 21/18639 0.142857142857143 2.57515888366952 0.107713818959834 0.39358624666643 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/1034 21/18639 0.142857142857143 2.57515888366952 0.107713818959834 0.39358624666643 GO:0071889 14-3-3 protein binding 4/1034 33/18639 0.121212121212121 2.18498329523475 0.107933478694051 0.39358624666643 GO:0099106 ion channel regulator activity 13/1034 160/18639 0.08125 1.46462161508704 0.108207641871506 0.39358624666643 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 20/1034 268/18639 0.0746268656716418 1.34523225266318 0.10955498722676 0.397088778264011 GO:0031072 heat shock protein binding 11/1034 131/18639 0.083969465648855 1.51364300795842 0.111603236526655 0.403098403258863 GO:0008238 exopeptidase activity 9/1034 102/18639 0.0882352941176471 1.59053931050176 0.112859496624053 0.40621554011375 GO:0008083 growth factor activity 13/1034 162/18639 0.0802469135802469 1.44653986675263 0.11605768921251 0.416276364432371 GO:0015035 protein-disulfide reductase activity 4/1034 34/18639 0.117647058823529 2.12071908066902 0.117255029315565 0.417538657959934 GO:0051427 hormone receptor binding 4/1034 34/18639 0.117647058823529 2.12071908066902 0.117255029315565 0.417538657959934 GO:0005504 fatty acid binding 5/1034 47/18639 0.106382978723404 1.9176715091156 0.117622216327532 0.417538657959934 GO:0031683 G-protein beta/gamma-subunit complex binding 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.420648264466074 GO:0005114 type II transforming growth factor beta receptor binding 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.420648264466074 GO:0008526 phosphatidylinositol transfer activity 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.420648264466074 GO:0015205 nucleobase transmembrane transporter activity 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.420648264466074 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.420648264466074 GO:0019203 carbohydrate phosphatase activity 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.420648264466074 GO:0050998 nitric-oxide synthase binding 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.420648264466074 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/1034 23/18639 0.130434782608696 2.35123202422 0.132425735830014 0.454471046885064 GO:0043274 phospholipase binding 3/1034 23/18639 0.130434782608696 2.35123202422 0.132425735830014 0.454471046885064 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 3/1034 23/18639 0.130434782608696 2.35123202422 0.132425735830014 0.454471046885064 GO:0001222 transcription corepressor binding 5/1034 49/18639 0.102040816326531 1.83939920262109 0.133967420288338 0.458239553502824 GO:0043178 alcohol binding 8/1034 92/18639 0.0869565217391304 1.56748801614667 0.137944996360964 0.465112737201124 GO:0005527 macrolide binding 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.465112737201124 GO:0008603 cAMP-dependent protein kinase regulator activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.465112737201124 GO:0015132 prostaglandin transmembrane transporter activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.465112737201124 GO:0015269 calcium-activated potassium channel activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.465112737201124 GO:0016208 AMP binding 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.465112737201124 GO:0016840 carbon-nitrogen lyase activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.465112737201124 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.465112737201124 GO:0070008 serine-type exopeptidase activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.465112737201124 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.465112737201124 GO:0003774 cytoskeletal motor activity 12/1034 153/18639 0.0784313725490196 1.41381272044601 0.143238538067622 0.47101558522864 GO:0005540 hyaluronic acid binding 3/1034 24/18639 0.125 2.25326402321083 0.145453990017363 0.47101558522864 GO:0015149 hexose transmembrane transporter activity 3/1034 24/18639 0.125 2.25326402321083 0.145453990017363 0.47101558522864 GO:0035035 histone acetyltransferase binding 3/1034 24/18639 0.125 2.25326402321083 0.145453990017363 0.47101558522864 GO:0050699 WW domain binding 3/1034 24/18639 0.125 2.25326402321083 0.145453990017363 0.47101558522864 GO:0055056 D-glucose transmembrane transporter activity 3/1034 24/18639 0.125 2.25326402321083 0.145453990017363 0.47101558522864 GO:0060229 lipase activator activity 3/1034 24/18639 0.125 2.25326402321083 0.145453990017363 0.47101558522864 GO:0120013 lipid transfer activity 6/1034 65/18639 0.0923076923076923 1.66394881714031 0.150754375555208 0.486653968589155 GO:0000146 microfilament motor activity 4/1034 38/18639 0.105263157894737 1.89748549323017 0.157743890664108 0.504666186521486 GO:0004709 MAP kinase kinase kinase activity 3/1034 25/18639 0.12 2.1631334622824 0.158879457551191 0.504666186521486 GO:0017025 TBP-class protein binding 3/1034 25/18639 0.12 2.1631334622824 0.158879457551191 0.504666186521486 GO:0005035 death receptor activity 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.504666186521486 GO:0017154 semaphorin receptor activity 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.504666186521486 GO:0035673 oligopeptide transmembrane transporter activity 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.504666186521486 GO:0089720 caspase binding 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.504666186521486 GO:0030159 signaling receptor complex adaptor activity 5/1034 52/18639 0.0961538461538462 1.73328001785449 0.16024250646568 0.504666186521486 GO:0051018 protein kinase A binding 5/1034 53/18639 0.0943396226415094 1.70057662129119 0.16943307785147 0.530839268032352 GO:0005227 calcium-activated cation channel activity 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.530839268032352 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.530839268032352 GO:0008198 ferrous iron binding 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.530839268032352 GO:0015145 monosaccharide transmembrane transporter activity 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.530839268032352 GO:0030507 spectrin binding 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.530839268032352 GO:0051139 metal cation:proton antiporter activity 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.530839268032352 GO:0070006 metalloaminopeptidase activity 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.530839268032352 GO:0005548 phospholipid transporter activity 6/1034 68/18639 0.0882352941176471 1.59053931050176 0.174791072451831 0.532622943488913 GO:0032934 sterol binding 6/1034 68/18639 0.0882352941176471 1.59053931050176 0.174791072451831 0.532622943488913 GO:1990841 promoter-specific chromatin binding 6/1034 68/18639 0.0882352941176471 1.59053931050176 0.174791072451831 0.532622943488913 GO:0015485 cholesterol binding 5/1034 54/18639 0.0925925925925926 1.66908446163765 0.178823533775589 0.536939749384009 GO:0004177 aminopeptidase activity 4/1034 40/18639 0.1 1.80261121856867 0.179678724335333 0.536939749384009 GO:0015144 carbohydrate transmembrane transporter activity 4/1034 40/18639 0.1 1.80261121856867 0.179678724335333 0.536939749384009 GO:0016530 metallochaperone activity 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.536939749384009 GO:0032036 myosin heavy chain binding 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.536939749384009 GO:0034236 protein kinase A catalytic subunit binding 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.536939749384009 GO:0044548 S100 protein binding 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.536939749384009 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.536939749384009 GO:0140828 metal cation:monoatomic cation antiporter activity 4/1034 41/18639 0.0975609756097561 1.7586450912865 0.191007986458068 0.566986350606851 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/1034 15/18639 0.133333333333333 2.40348162475822 0.200887117422394 0.588046937376895 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/1034 15/18639 0.133333333333333 2.40348162475822 0.200887117422394 0.588046937376895 GO:0005523 tropomyosin binding 2/1034 15/18639 0.133333333333333 2.40348162475822 0.200887117422394 0.588046937376895 GO:0051119 sugar transmembrane transporter activity 3/1034 28/18639 0.107142857142857 1.93136916275214 0.20116098199149 0.588046937376895 GO:0051959 dynein light intermediate chain binding 3/1034 28/18639 0.107142857142857 1.93136916275214 0.20116098199149 0.588046937376895 GO:0019208 phosphatase regulator activity 9/1034 117/18639 0.0769230769230769 1.38662401428359 0.201518505161104 0.588046937376895 GO:0005518 collagen binding 6/1034 72/18639 0.0833333333333333 1.50217601547389 0.209053485953579 0.608316199971964 GO:0004712 protein serine/threonine/tyrosine kinase activity 4/1034 43/18639 0.0930232558139535 1.67684764518015 0.214300887751169 0.620091924501283 GO:0008375 acetylglucosaminyltransferase activity 4/1034 43/18639 0.0930232558139535 1.67684764518015 0.214300887751169 0.620091924501283 GO:0016651 oxidoreductase activity, acting on NAD(P)H 7/1034 88/18639 0.0795454545454545 1.4338952874978 0.215693904195036 0.620951464545079 GO:0099604 ligand-gated calcium channel activity 3/1034 29/18639 0.103448275862069 1.86477022610552 0.215800170156518 0.620951464545079 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.627315902287264 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.627315902287264 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.627315902287264 GO:0015385 sodium:proton antiporter activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.627315902287264 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.627315902287264 GO:0140328 floppase activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.627315902287264 GO:0019838 growth factor binding 10/1034 136/18639 0.0735294117647059 1.32544942541814 0.223184960566265 0.628201809986244 GO:0140789 histone phosphatase activity 10/1034 136/18639 0.0735294117647059 1.32544942541814 0.223184960566265 0.628201809986244 GO:0016922 nuclear receptor binding 10/1034 137/18639 0.072992700729927 1.31577461209392 0.229769527675291 0.643957267972821 GO:0022839 monoatomic ion-gated channel activity 3/1034 30/18639 0.1 1.80261121856867 0.230652651645638 0.643957267972821 GO:0070566 adenylyltransferase activity 3/1034 30/18639 0.1 1.80261121856867 0.230652651645638 0.643957267972821 GO:0000149 SNARE binding 8/1034 106/18639 0.0754716981132075 1.36046129703296 0.234856984335075 0.653927937515182 GO:0008514 organic anion transmembrane transporter activity 18/1034 269/18639 0.0669144981412639 1.20620825034334 0.238257955164719 0.655985190588893 GO:0140303 intramembrane lipid transporter activity 4/1034 45/18639 0.0888888888888889 1.60232108317215 0.238320148919554 0.655985190588893 GO:0001098 basal transcription machinery binding 5/1034 60/18639 0.0833333333333333 1.50217601547389 0.238780909529822 0.655985190588893 GO:0001099 basal RNA polymerase II transcription machinery binding 5/1034 60/18639 0.0833333333333333 1.50217601547389 0.238780909529822 0.655985190588893 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.655985190588893 GO:0008484 sulfuric ester hydrolase activity 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.655985190588893 GO:0015278 intracellularly gated calcium channel activity 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.655985190588893 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.655985190588893 GO:0017110 nucleoside diphosphate phosphatase activity 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.655985190588893 GO:0019198 transmembrane receptor protein phosphatase activity 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.655985190588893 GO:0038191 neuropilin binding 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.655985190588893 GO:0046943 carboxylic acid transmembrane transporter activity 13/1034 188/18639 0.0691489361702128 1.24648648092514 0.245251867472221 0.660257246881609 GO:0017022 myosin binding 6/1034 76/18639 0.0789473684210526 1.42311411992263 0.245439286352892 0.660257246881609 GO:0004180 carboxypeptidase activity 4/1034 46/18639 0.0869565217391304 1.56748801614667 0.250557679208506 0.671949106812039 GO:0005342 organic acid transmembrane transporter activity 13/1034 189/18639 0.0687830687830688 1.2398913143594 0.251086500706144 0.671949106812039 GO:0140359 ABC-type transporter activity 4/1034 47/18639 0.0851063829787234 1.53413720729248 0.26292376877883 0.692825925708292 GO:0008525 phosphatidylcholine transporter activity 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.692825925708292 GO:0015172 acidic amino acid transmembrane transporter activity 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.692825925708292 GO:0017075 syntaxin-1 binding 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.692825925708292 GO:0017128 phospholipid scramblase activity 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.692825925708292 GO:0034185 apolipoprotein binding 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.692825925708292 GO:0070064 proline-rich region binding 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.692825925708292 GO:0042826 histone deacetylase binding 9/1034 127/18639 0.0708661417322835 1.27744102103291 0.272712631717693 0.715005453209078 GO:0140693 molecular condensate scaffold activity 4/1034 48/18639 0.0833333333333333 1.50217601547389 0.27540120709125 0.720226447912053 GO:0140416 transcription regulator inhibitor activity 3/1034 33/18639 0.0909090909090909 1.63873747142606 0.276155370899566 0.72037499530114 GO:0008381 mechanosensitive monoatomic ion channel activity 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.734944796840781 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.734944796840781 GO:0030506 ankyrin binding 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.734944796840781 GO:0043395 heparan sulfate proteoglycan binding 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.734944796840781 GO:0004674 protein serine/threonine kinase activity 27/1034 433/18639 0.0623556581986143 1.12403009010055 0.291759117191688 0.751588947778089 GO:0016298 lipase activity 9/1034 130/18639 0.0692307692307692 1.24796161285523 0.295406315875782 0.757207752604673 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 9/1034 130/18639 0.0692307692307692 1.24796161285523 0.295406315875782 0.757207752604673 GO:0008235 metalloexopeptidase activity 5/1034 66/18639 0.0757575757575758 1.36561455952172 0.303250196534118 0.775389735197386 GO:0001972 retinoic acid binding 2/1034 20/18639 0.1 1.80261121856867 0.305528836675937 0.779287131570971 GO:0061631 ubiquitin conjugating enzyme activity 3/1034 35/18639 0.0857142857142857 1.54509533020171 0.306965962680416 0.781024235095739 GO:0005484 SNAP receptor activity 3/1034 36/18639 0.0833333333333333 1.50217601547389 0.322427332237477 0.818347504180133 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.820245909084402 GO:0005123 death receptor binding 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.820245909084402 GO:0015125 bile acid transmembrane transporter activity 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.820245909084402 GO:0072542 protein phosphatase activator activity 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.820245909084402 GO:0015078 proton transmembrane transporter activity 12/1034 185/18639 0.0648648648648649 1.16926133096346 0.330493830835592 0.828641085565939 GO:0046906 tetrapyrrole binding 10/1034 152/18639 0.0657894736842105 1.18592843326886 0.335738887307876 0.839753681813647 GO:0005246 calcium channel regulator activity 4/1034 53/18639 0.0754716981132075 1.36046129703296 0.338880664070556 0.845564555519045 GO:0008234 cysteine-type peptidase activity 12/1034 187/18639 0.0641711229946524 1.1567558621831 0.343865599061538 0.855935334531491 GO:0015377 chloride:monoatomic cation symporter activity 2/1034 22/18639 0.0909090909090909 1.63873747142606 0.347003321732683 0.859602952877366 GO:0140517 protein-RNA adaptor activity 2/1034 22/18639 0.0909090909090909 1.63873747142606 0.347003321732683 0.859602952877366 GO:0140463 chromatin-protein adaptor activity 4/1034 54/18639 0.0740740740740741 1.33526756931012 0.351685234494154 0.86902864918675 GO:0008081 phosphoric diester hydrolase activity 6/1034 87/18639 0.0689655172413793 1.24318015073701 0.352571921184999 0.86902864918675 GO:0042887 amide transmembrane transporter activity 3/1034 38/18639 0.0789473684210526 1.42311411992263 0.353332074209521 0.86902864918675 GO:0106310 protein serine kinase activity 22/1034 361/18639 0.0609418282548476 1.09854423292273 0.355254481300535 0.871681423238605 GO:0015108 chloride transmembrane transporter activity 8/1034 121/18639 0.0661157024793388 1.19180907012804 0.357086177250803 0.873892727647703 GO:0008201 heparin binding 11/1034 172/18639 0.063953488372093 1.15283275606136 0.357847651302012 0.873892727647703 GO:0016849 phosphorus-oxygen lyase activity 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.888128231148294 GO:0042171 lysophosphatidic acid acyltransferase activity 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.888128231148294 GO:0071617 lysophospholipid acyltransferase activity 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.888128231148294 GO:0140103 catalytic activity, acting on a glycoprotein 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.888128231148294 GO:0003727 single-stranded RNA binding 6/1034 89/18639 0.0674157303370786 1.21524351813618 0.372617752713865 0.888128231148294 GO:0019212 phosphatase inhibitor activity 4/1034 56/18639 0.0714285714285714 1.28757944183476 0.377286122472127 0.888128231148294 GO:0043539 protein serine/threonine kinase activator activity 5/1034 73/18639 0.0684931506849315 1.23466521819772 0.381094045706058 0.888128231148294 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/1034 40/18639 0.075 1.3519584139265 0.384055975761852 0.888128231148294 GO:0005315 phosphate transmembrane transporter activity 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.888128231148294 GO:0015295 solute:proton symporter activity 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.888128231148294 GO:0030215 semaphorin receptor binding 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.888128231148294 GO:0050431 transforming growth factor beta binding 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.888128231148294 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.888128231148294 GO:0020037 heme binding 9/1034 142/18639 0.0633802816901408 1.1425000681069 0.389721693374404 0.888128231148294 GO:0005496 steroid binding 7/1034 108/18639 0.0648148148148148 1.16835912314636 0.392185822545357 0.888128231148294 GO:0046982 protein heterodimerization activity 22/1034 369/18639 0.0596205962059621 1.0747275557862 0.3946190757859 0.888128231148294 GO:0001727 lipid kinase activity 3/1034 41/18639 0.0731707317073171 1.31898381846488 0.399296606496362 0.888128231148294 GO:0061650 ubiquitin-like protein conjugating enzyme activity 3/1034 41/18639 0.0731707317073171 1.31898381846488 0.399296606496362 0.888128231148294 GO:0000287 magnesium ion binding 14/1034 230/18639 0.0608695652173913 1.09724161130267 0.399505128026012 0.888128231148294 GO:0044183 protein folding chaperone 5/1034 75/18639 0.0666666666666667 1.20174081237911 0.40340887066357 0.888128231148294 GO:0003707 nuclear steroid receptor activity 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.888128231148294 GO:0005251 delayed rectifier potassium channel activity 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.888128231148294 GO:0008139 nuclear localization sequence binding 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.888128231148294 GO:0015271 outward rectifier potassium channel activity 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.888128231148294 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.888128231148294 GO:0019211 phosphatase activator activity 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.888128231148294 GO:0051213 dioxygenase activity 6/1034 93/18639 0.0645161290322581 1.16297497972172 0.412754289257323 0.888128231148294 GO:0004520 DNA endonuclease activity 3/1034 42/18639 0.0714285714285714 1.28757944183476 0.414430600177289 0.888128231148294 GO:0048487 beta-tubulin binding 3/1034 42/18639 0.0714285714285714 1.28757944183476 0.414430600177289 0.888128231148294 GO:0051879 Hsp90 protein binding 3/1034 42/18639 0.0714285714285714 1.28757944183476 0.414430600177289 0.888128231148294 GO:0001786 phosphatidylserine binding 4/1034 59/18639 0.0677966101694915 1.22210930072452 0.415469115188887 0.888128231148294 GO:0070888 E-box binding 4/1034 59/18639 0.0677966101694915 1.22210930072452 0.415469115188887 0.888128231148294 GO:0031490 chromatin DNA binding 8/1034 128/18639 0.0625 1.12663201160542 0.416721637138637 0.888128231148294 GO:0042562 hormone binding 6/1034 94/18639 0.0638297872340425 1.15060290546936 0.422760000996763 0.888128231148294 GO:0005112 Notch binding 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.888128231148294 GO:0034237 protein kinase A regulatory subunit binding 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.888128231148294 GO:0050681 nuclear androgen receptor binding 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.888128231148294 GO:0050750 low-density lipoprotein particle receptor binding 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.888128231148294 GO:0052742 phosphatidylinositol kinase activity 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.888128231148294 GO:0120014 phospholipid transfer activity 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.888128231148294 GO:0048156 tau protein binding 3/1034 43/18639 0.0697674418604651 1.25763573388512 0.429440328609249 0.888128231148294 GO:0016829 lyase activity 12/1034 200/18639 0.06 1.0815667311412 0.432395799760965 0.888128231148294 GO:0015103 inorganic anion transmembrane transporter activity 10/1034 165/18639 0.0606060606060606 1.09249164761737 0.433400177205777 0.888128231148294 GO:0016798 hydrolase activity, acting on glycosyl bonds 8/1034 130/18639 0.0615384615384615 1.10929921142687 0.433760333276528 0.888128231148294 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0003796 lysozyme activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0004090 carbonyl reductase (NADPH) activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0008190 eukaryotic initiation factor 4E binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0015279 store-operated calcium channel activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0030957 Tat protein binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0031419 cobalamin binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0031434 mitogen-activated protein kinase kinase binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0031996 thioesterase binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0032052 bile acid binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0035256 G protein-coupled glutamate receptor binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0035374 chondroitin sulfate binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0043121 neurotrophin binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0070513 death domain binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:1905394 retromer complex binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.888128231148294 GO:0019905 syntaxin binding 4/1034 61/18639 0.0655737704918033 1.18204014332372 0.44063803209363 0.888128231148294 GO:0015399 primary active transmembrane transporter activity 10/1034 166/18639 0.0602409638554217 1.08591037263173 0.440940670317688 0.888128231148294 GO:0008509 monoatomic anion transmembrane transporter activity 9/1034 149/18639 0.0604026845637584 1.08882556826295 0.44565218621053 0.888128231148294 GO:0004364 glutathione transferase activity 2/1034 27/18639 0.0740740740740741 1.33526756931012 0.446305576552081 0.888128231148294 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/1034 27/18639 0.0740740740740741 1.33526756931012 0.446305576552081 0.888128231148294 GO:0015179 L-amino acid transmembrane transporter activity 4/1034 62/18639 0.0645161290322581 1.16297497972172 0.45310372624694 0.888128231148294 GO:0042578 phosphoric ester hydrolase activity 21/1034 363/18639 0.0578512396694215 1.04283293636204 0.453517026613165 0.888128231148294 GO:0015276 ligand-gated monoatomic ion channel activity 11/1034 186/18639 0.0591397849462366 1.06606039807824 0.458007432629753 0.888128231148294 GO:0141110 transporter inhibitor activity 3/1034 45/18639 0.0666666666666667 1.20174081237911 0.459022998767057 0.888128231148294 GO:0003714 transcription corepressor activity 12/1034 204/18639 0.0588235294117647 1.06035954033451 0.459743471809545 0.888128231148294 GO:0045499 chemorepellent activity 2/1034 28/18639 0.0714285714285714 1.28757944183476 0.465162853056741 0.888128231148294 GO:0046966 nuclear thyroid hormone receptor binding 2/1034 28/18639 0.0714285714285714 1.28757944183476 0.465162853056741 0.888128231148294 GO:0051393 alpha-actinin binding 2/1034 28/18639 0.0714285714285714 1.28757944183476 0.465162853056741 0.888128231148294 GO:0141052 histone H3 demethylase activity 2/1034 28/18639 0.0714285714285714 1.28757944183476 0.465162853056741 0.888128231148294 GO:0005507 copper ion binding 4/1034 63/18639 0.0634920634920635 1.14451505940868 0.46547696633798 0.888128231148294 GO:1901682 sulfur compound transmembrane transporter activity 4/1034 63/18639 0.0634920634920635 1.14451505940868 0.46547696633798 0.888128231148294 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0003953 NAD+ nucleosidase activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0008432 JUN kinase binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0008503 benzodiazepine receptor activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0010854 adenylate cyclase regulator activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0019215 intermediate filament binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0031731 CCR6 chemokine receptor binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0032050 clathrin heavy chain binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0032794 GTPase activating protein binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0034511 U3 snoRNA binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0043522 leucine zipper domain binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0045294 alpha-catenin binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0047676 arachidonate-CoA ligase activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0048185 activin binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0070697 activin receptor binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0070990 snRNP binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0097493 structural molecule activity conferring elasticity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0140537 transcription regulator activator activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.888128231148294 GO:0015101 organic cation transmembrane transporter activity 5/1034 81/18639 0.0617283950617284 1.1127229744251 0.469509428313309 0.888128231148294 GO:0033192 calmodulin-dependent protein phosphatase activity 5/1034 81/18639 0.0617283950617284 1.1127229744251 0.469509428313309 0.888128231148294 GO:0140791 histone H2AXS140 phosphatase activity 5/1034 81/18639 0.0617283950617284 1.1127229744251 0.469509428313309 0.888128231148294 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 5/1034 81/18639 0.0617283950617284 1.1127229744251 0.469509428313309 0.888128231148294 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 5/1034 81/18639 0.0617283950617284 1.1127229744251 0.469509428313309 0.888128231148294 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 5/1034 81/18639 0.0617283950617284 1.1127229744251 0.469509428313309 0.888128231148294 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 5/1034 81/18639 0.0617283950617284 1.1127229744251 0.469509428313309 0.888128231148294 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 5/1034 81/18639 0.0617283950617284 1.1127229744251 0.469509428313309 0.888128231148294 GO:1990439 MAP kinase serine/threonine phosphatase activity 5/1034 81/18639 0.0617283950617284 1.1127229744251 0.469509428313309 0.888128231148294 GO:0022834 ligand-gated channel activity 11/1034 188/18639 0.0585106382978723 1.05471933001358 0.472260350228537 0.888128231148294 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/1034 46/18639 0.0652173913043478 1.17561601211 0.473567090829281 0.888128231148294 GO:0030276 clathrin binding 3/1034 46/18639 0.0652173913043478 1.17561601211 0.473567090829281 0.888128231148294 GO:0030291 protein serine/threonine kinase inhibitor activity 3/1034 46/18639 0.0652173913043478 1.17561601211 0.473567090829281 0.888128231148294 GO:0004536 DNA nuclease activity 4/1034 64/18639 0.0625 1.12663201160542 0.47774849487853 0.888128231148294 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 5/1034 82/18639 0.0609756097560976 1.09915318205406 0.480324014776947 0.888128231148294 GO:0033549 MAP kinase phosphatase activity 5/1034 82/18639 0.0609756097560976 1.09915318205406 0.480324014776947 0.888128231148294 GO:0016779 nucleotidyltransferase activity 8/1034 136/18639 0.0588235294117647 1.06035954033451 0.484418930676922 0.888128231148294 GO:0099094 ligand-gated monoatomic cation channel activity 8/1034 136/18639 0.0588235294117647 1.06035954033451 0.484418930676922 0.888128231148294 GO:0043495 protein-membrane adaptor activity 3/1034 47/18639 0.0638297872340425 1.15060290546936 0.48792913551454 0.888128231148294 GO:0099095 ligand-gated monoatomic anion channel activity 3/1034 47/18639 0.0638297872340425 1.15060290546936 0.48792913551454 0.888128231148294 GO:0045296 cadherin binding 19/1034 334/18639 0.0568862275449102 1.02543751954505 0.488916956063772 0.888128231148294 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 5/1034 83/18639 0.0602409638554217 1.08591037263173 0.49106276555994 0.888128231148294 GO:0005254 chloride channel activity 5/1034 83/18639 0.0602409638554217 1.08591037263173 0.49106276555994 0.888128231148294 GO:0004000 adenosine deaminase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0004300 enoyl-CoA hydratase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0004859 phospholipase inhibitor activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0005049 nuclear export signal receptor activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0005165 neurotrophin receptor binding 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0008179 adenylate cyclase binding 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0015166 polyol transmembrane transporter activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0015368 calcium:monoatomic cation antiporter activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0016423 tRNA (guanine) methyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0016801 hydrolase activity, acting on ether bonds 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0016803 ether hydrolase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0035197 siRNA binding 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:1990459 transferrin receptor binding 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.888128231148294 GO:0022836 gated channel activity 18/1034 318/18639 0.0566037735849057 1.02034597277472 0.499693108114189 0.888128231148294 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.888128231148294 GO:0031210 phosphatidylcholine binding 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.888128231148294 GO:0032452 histone demethylase activity 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.888128231148294 GO:0033612 receptor serine/threonine kinase binding 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.888128231148294 GO:0048019 receptor antagonist activity 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.888128231148294 GO:0051721 protein phosphatase 2A binding 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.888128231148294 GO:0017018 myosin phosphatase activity 5/1034 84/18639 0.0595238095238095 1.07298286819563 0.501719594326508 0.888128231148294 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/1034 48/18639 0.0625 1.12663201160542 0.502097664076093 0.888128231148294 GO:0032266 phosphatidylinositol-3-phosphate binding 3/1034 48/18639 0.0625 1.12663201160542 0.502097664076093 0.888128231148294 GO:0035403 histone H3T6 kinase activity 14/1034 247/18639 0.0566801619433198 1.02172295789317 0.506342899554501 0.889243423452492 GO:0004721 phosphoprotein phosphatase activity 10/1034 175/18639 0.0571428571428571 1.03006355346781 0.50806770822649 0.889243423452492 GO:0005253 monoatomic anion channel activity 6/1034 103/18639 0.058252427184466 1.05006478751573 0.511080529625036 0.889243423452492 GO:0004679 AMP-activated protein kinase activity 14/1034 248/18639 0.0564516129032258 1.0176031072565 0.512530405961555 0.889243423452492 GO:0035254 glutamate receptor binding 3/1034 49/18639 0.0612244897959184 1.10363952157265 0.51606230960813 0.889243423452492 GO:0016757 glycosyltransferase activity 15/1034 267/18639 0.0561797752808989 1.01270293178015 0.517946993363249 0.889243423452492 GO:0016411 acylglycerol O-acyltransferase activity 2/1034 31/18639 0.0645161290322581 1.16297497972172 0.51936081564456 0.889243423452492 GO:0047499 calcium-independent phospholipase A2 activity 2/1034 31/18639 0.0645161290322581 1.16297497972172 0.51936081564456 0.889243423452492 GO:0070273 phosphatidylinositol-4-phosphate binding 2/1034 31/18639 0.0645161290322581 1.16297497972172 0.51936081564456 0.889243423452492 GO:0070325 lipoprotein particle receptor binding 2/1034 31/18639 0.0645161290322581 1.16297497972172 0.51936081564456 0.889243423452492 GO:0140457 protein demethylase activity 2/1034 31/18639 0.0645161290322581 1.16297497972172 0.51936081564456 0.889243423452492 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.889243423452492 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.889243423452492 GO:0019855 calcium channel inhibitor activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.889243423452492 GO:0031432 titin binding 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.889243423452492 GO:0039706 co-receptor binding 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.889243423452492 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.889243423452492 GO:0061459 L-arginine transmembrane transporter activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.889243423452492 GO:0070700 BMP receptor binding 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.889243423452492 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.889243423452492 GO:0140333 glycerophospholipid flippase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.889243423452492 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.889243423452492 GO:0140852 histone ubiquitin ligase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.889243423452492 GO:0022884 macromolecule transmembrane transporter activity 2/1034 32/18639 0.0625 1.12663201160542 0.53659403858032 0.889243423452492 GO:0031369 translation initiation factor binding 2/1034 32/18639 0.0625 1.12663201160542 0.53659403858032 0.889243423452492 GO:0042910 xenobiotic transmembrane transporter activity 2/1034 32/18639 0.0625 1.12663201160542 0.53659403858032 0.889243423452492 GO:0008013 beta-catenin binding 6/1034 106/18639 0.0566037735849057 1.02034597277472 0.539436344334374 0.889243423452492 GO:0022843 voltage-gated monoatomic cation channel activity 8/1034 143/18639 0.0559440559440559 1.00845382856988 0.541887788613991 0.889243423452492 GO:0030544 Hsp70 protein binding 3/1034 51/18639 0.0588235294117647 1.06035954033451 0.543343714408873 0.889243423452492 GO:0019888 protein phosphatase regulator activity 6/1034 107/18639 0.0560747663551402 1.01081002910392 0.548730063721822 0.889243423452492 GO:0004065 arylsulfatase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0005313 L-glutamate transmembrane transporter activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0008474 palmitoyl-(protein) hydrolase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0008494 translation activator activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0008559 ABC-type xenobiotic transporter activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0015386 potassium:proton antiporter activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0042043 neurexin family protein binding 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0042813 Wnt receptor activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0043176 amine binding 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0046030 inositol trisphosphate phosphatase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0061783 peptidoglycan muralytic activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0071933 Arp2/3 complex binding 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0098599 palmitoyl hydrolase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.889243423452492 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/1034 33/18639 0.0606060606060606 1.09249164761737 0.553396533269401 0.889243423452492 GO:0022804 active transmembrane transporter activity 25/1034 457/18639 0.0547045951859956 0.986111169895331 0.558720654195804 0.889243423452492 GO:0004519 endonuclease activity 7/1034 127/18639 0.0551181102362205 0.993565238581154 0.561969244879271 0.889243423452492 GO:0015631 tubulin binding 21/1034 385/18639 0.0545454545454545 0.983242482855636 0.564273223497906 0.889243423452492 GO:1901681 sulfur compound binding 15/1034 275/18639 0.0545454545454545 0.983242482855636 0.564838850299901 0.889243423452492 GO:0004620 phospholipase activity 6/1034 109/18639 0.055045871559633 0.992263056092843 0.567058412075797 0.889243423452492 GO:0004864 protein phosphatase inhibitor activity 3/1034 53/18639 0.0566037735849057 1.02034597277472 0.56971067948567 0.889243423452492 GO:0008146 sulfotransferase activity 3/1034 53/18639 0.0566037735849057 1.02034597277472 0.56971067948567 0.889243423452492 GO:0038064 collagen receptor activity 3/1034 53/18639 0.0566037735849057 1.02034597277472 0.56971067948567 0.889243423452492 GO:1901505 carbohydrate derivative transmembrane transporter activity 3/1034 53/18639 0.0566037735849057 1.02034597277472 0.56971067948567 0.889243423452492 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/1034 34/18639 0.0588235294117647 1.06035954033451 0.569763015141806 0.889243423452492 GO:0090482 vitamin transmembrane transporter activity 2/1034 34/18639 0.0588235294117647 1.06035954033451 0.569763015141806 0.889243423452492 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 7/1034 128/18639 0.0546875 0.985803010154739 0.570371999046085 0.889243423452492 GO:0008017 microtubule binding 15/1034 276/18639 0.0543478260869565 0.979680010091666 0.570586005061827 0.889243423452492 GO:0015085 calcium ion transmembrane transporter activity 8/1034 147/18639 0.054421768707483 0.98101290806458 0.573572922586406 0.889243423452492 GO:0072341 modified amino acid binding 5/1034 91/18639 0.0549450549450549 0.990445724488278 0.573576277996244 0.889243423452492 GO:0000774 adenyl-nucleotide exchange factor activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0004467 long-chain fatty acid-CoA ligase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0015116 sulfate transmembrane transporter activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0015250 water channel activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0016846 carbon-sulfur lyase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0017081 chloride channel regulator activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0031386 protein tag activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0033130 acetylcholine receptor binding 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0034483 heparan sulfate sulfotransferase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0047372 monoacylglycerol lipase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0050780 dopamine receptor binding 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0051371 muscle alpha-actinin binding 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0061578 K63-linked deubiquitinase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0140161 monocarboxylate:sodium symporter activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0140776 protein-containing complex destabilizing activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0141047 molecular tag activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.889243423452492 GO:0051287 NAD binding 3/1034 54/18639 0.0555555555555556 1.00145067698259 0.582535705661642 0.889243423452492 GO:0052689 carboxylic ester hydrolase activity 5/1034 92/18639 0.0543478260869565 0.979680010091666 0.583394976352316 0.889243423452492 GO:0004623 phospholipase A2 activity 2/1034 35/18639 0.0571428571428571 1.03006355346781 0.585690109230375 0.889243423452492 GO:0043015 gamma-tubulin binding 2/1034 35/18639 0.0571428571428571 1.03006355346781 0.585690109230375 0.889243423452492 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 13/1034 243/18639 0.0534979423868313 0.964359911168422 0.59409070998655 0.889243423452492 GO:0008374 O-acyltransferase activity 3/1034 55/18639 0.0545454545454545 0.983242482855636 0.59511517164188 0.889243423452492 GO:0005262 calcium channel activity 7/1034 131/18639 0.0534351145038168 0.963227368700813 0.595115252231646 0.889243423452492 GO:0004708 MAP kinase kinase activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.889243423452492 GO:0008142 oxysterol binding 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.889243423452492 GO:0008296 3'-5'-DNA exonuclease activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.889243423452492 GO:0015378 sodium:chloride symporter activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.889243423452492 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.889243423452492 GO:0016722 oxidoreductase activity, acting on metal ions 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.889243423452492 GO:0022841 potassium ion leak channel activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.889243423452492 GO:0022858 alanine transmembrane transporter activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.889243423452492 GO:0030275 LRR domain binding 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.889243423452492 GO:0055102 lipase inhibitor activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.889243423452492 GO:0070411 I-SMAD binding 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.889243423452492 GO:0140327 flippase activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.889243423452492 GO:0004033 aldo-keto reductase (NADPH) activity 2/1034 36/18639 0.0555555555555556 1.00145067698259 0.601176154935839 0.889243423452492 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 2/1034 36/18639 0.0555555555555556 1.00145067698259 0.601176154935839 0.889243423452492 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/1034 36/18639 0.0555555555555556 1.00145067698259 0.601176154935839 0.889243423452492 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/1034 36/18639 0.0555555555555556 1.00145067698259 0.601176154935839 0.889243423452492 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/1034 36/18639 0.0555555555555556 1.00145067698259 0.601176154935839 0.889243423452492 GO:0004676 3-phosphoinositide-dependent protein kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0004711 ribosomal protein S6 kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0035175 histone H3S10 kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0035979 histone H2AXS139 kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0044022 histone H3S28 kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0044023 histone H4S1 kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0044024 histone H2AS1 kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0044025 histone H2BS14 kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0072354 histone H3T3 kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0072371 histone H2AS121 kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0072518 Rho-dependent protein serine/threonine kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0140823 histone H2BS36 kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0140855 histone H3S57 kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0140995 histone H2A kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0140997 histone H4 kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0140998 histone H2B kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:1990244 histone H2AT120 kinase activity 13/1034 245/18639 0.0530612244897959 0.956487585362965 0.606028431859201 0.889243423452492 GO:0030170 pyridoxal phosphate binding 3/1034 56/18639 0.0535714285714286 0.965684581376071 0.6074451178213 0.890057881857309 GO:0004677 DNA-dependent protein kinase activity 13/1034 246/18639 0.0528455284552846 0.952599424446856 0.611936544644127 0.894102476120768 GO:0140857 histone H3T45 kinase activity 13/1034 246/18639 0.0528455284552846 0.952599424446856 0.611936544644127 0.894102476120768 GO:0042805 actinin binding 2/1034 37/18639 0.0540540540540541 0.974384442469549 0.61622102654221 0.896188274510639 GO:0035402 histone H3T11 kinase activity 13/1034 247/18639 0.0526315789473684 0.948742746615087 0.617802858260217 0.896188274510639 GO:0070279 vitamin B6 binding 3/1034 57/18639 0.0526315789473684 0.948742746615087 0.619522317072613 0.896188274510639 GO:0016805 dipeptidase activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.896188274510639 GO:0031489 myosin V binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.896188274510639 GO:0032183 SUMO binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.896188274510639 GO:0051787 misfolded protein binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.896188274510639 GO:0070403 NAD+ binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.896188274510639 GO:1990226 histone methyltransferase binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.896188274510639 GO:0015297 antiporter activity 7/1034 135/18639 0.0518518518518519 0.934687298517086 0.626937005460308 0.9032439702099 GO:0005501 retinoid binding 2/1034 38/18639 0.0526315789473684 0.948742746615087 0.63082596833847 0.9063120613544 GO:0019840 isoprenoid binding 2/1034 38/18639 0.0526315789473684 0.948742746615087 0.63082596833847 0.9063120613544 GO:0015291 secondary active transmembrane transporter activity 15/1034 287/18639 0.0522648083623693 0.942131298903484 0.631698629404809 0.9063120613544 GO:0005249 voltage-gated potassium channel activity 5/1034 98/18639 0.0510204081632653 0.919699601310544 0.639618353047257 0.908395615848313 GO:0000900 mRNA regulatory element binding translation repressor activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.908395615848313 GO:0005372 water transmembrane transporter activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.908395615848313 GO:0015373 monoatomic anion:sodium symporter activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.908395615848313 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.908395615848313 GO:0035615 clathrin adaptor activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.908395615848313 GO:0050811 GABA receptor binding 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.908395615848313 GO:0098641 cadherin binding involved in cell-cell adhesion 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.908395615848313 GO:0099602 neurotransmitter receptor regulator activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.908395615848313 GO:1901611 phosphatidylglycerol binding 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.908395615848313 GO:0003712 transcription coregulator activity 26/1034 495/18639 0.0525252525252525 0.946826094601723 0.642824003083366 0.908395615848313 GO:0022853 active monoatomic ion transmembrane transporter activity 6/1034 118/18639 0.0508474576271186 0.916581975543389 0.644682710798648 0.908974388689078 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/1034 39/18639 0.0512820512820513 0.924416009522392 0.644993443280827 0.908974388689078 GO:0043130 ubiquitin binding 5/1034 100/18639 0.05 0.901305609284333 0.657276173505106 0.911897426362475 GO:0016791 phosphatase activity 14/1034 273/18639 0.0512820512820513 0.924416009522392 0.6577297617932 0.911897426362475 GO:0030331 nuclear estrogen receptor binding 2/1034 40/18639 0.05 0.901305609284333 0.658726994202878 0.911897426362475 GO:0032451 demethylase activity 2/1034 40/18639 0.05 0.901305609284333 0.658726994202878 0.911897426362475 GO:0050997 quaternary ammonium group binding 2/1034 40/18639 0.05 0.901305609284333 0.658726994202878 0.911897426362475 GO:0140662 ATP-dependent protein folding chaperone 2/1034 40/18639 0.05 0.901305609284333 0.658726994202878 0.911897426362475 GO:0032182 ubiquitin-like protein binding 6/1034 120/18639 0.05 0.901305609284333 0.660744824669264 0.911897426362475 GO:0003756 protein disulfide isomerase activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.911897426362475 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.911897426362475 GO:0008301 DNA binding, bending 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.911897426362475 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.911897426362475 GO:0022821 solute:potassium antiporter activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.911897426362475 GO:0022840 leak channel activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.911897426362475 GO:0022842 narrow pore channel activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.911897426362475 GO:0046624 sphingolipid transporter activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.911897426362475 GO:0140036 ubiquitin-modified protein reader activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.911897426362475 GO:1990380 K48-linked deubiquitinase activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.911897426362475 GO:0004540 RNA nuclease activity 6/1034 121/18639 0.0495867768595041 0.893856802596033 0.66860373977401 0.918729902314222 GO:0015079 potassium ion transmembrane transporter activity 8/1034 160/18639 0.05 0.901305609284333 0.668814023756336 0.918729902314222 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/1034 41/18639 0.0487804878048781 0.879322545643251 0.672031116649366 0.920700455568694 GO:0140318 protein transporter activity 2/1034 41/18639 0.0487804878048781 0.879322545643251 0.672031116649366 0.920700455568694 GO:0015171 amino acid transmembrane transporter activity 5/1034 102/18639 0.0490196078431373 0.883632950278758 0.674368360888202 0.922678830195381 GO:0008528 G protein-coupled peptide receptor activity 6/1034 122/18639 0.0491803278688525 0.886530107492786 0.676346319895041 0.922976247213073 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 9/1034 181/18639 0.0497237569060773 0.896326020282762 0.679411488359357 0.922976247213073 GO:0005216 monoatomic ion channel activity 23/1034 448/18639 0.0513392857142857 0.925447723818735 0.680385981670484 0.922976247213073 GO:0010851 cyclase regulator activity 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.922976247213073 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.922976247213073 GO:0043024 ribosomal small subunit binding 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.922976247213073 GO:0052745 inositol phosphate phosphatase activity 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.922976247213073 GO:0004722 protein serine/threonine phosphatase activity 5/1034 103/18639 0.0485436893203883 0.87505398959644 0.682699372687344 0.924283685433848 GO:0016859 cis-trans isomerase activity 2/1034 42/18639 0.0476190476190476 0.858386294556507 0.68491114247297 0.92606441122327 GO:0005267 potassium channel activity 6/1034 124/18639 0.0483870967741935 0.87223123479129 0.69147863263246 0.931119021888382 GO:0005245 voltage-gated calcium channel activity 2/1034 43/18639 0.0465116279069767 0.838423822590077 0.697373133393152 0.931119021888382 GO:0008200 ion channel inhibitor activity 2/1034 43/18639 0.0465116279069767 0.838423822590077 0.697373133393152 0.931119021888382 GO:0010314 phosphatidylinositol-5-phosphate binding 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.931119021888382 GO:0015174 basic amino acid transmembrane transporter activity 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.931119021888382 GO:0035613 RNA stem-loop binding 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.931119021888382 GO:0036122 BMP binding 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.931119021888382 GO:0051010 microtubule plus-end binding 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.931119021888382 GO:0051428 peptide hormone receptor binding 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.931119021888382 GO:0061891 calcium ion sensor activity 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.931119021888382 GO:0140312 cargo adaptor activity 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.931119021888382 GO:0016248 channel inhibitor activity 2/1034 44/18639 0.0454545454545455 0.81936873571303 0.709423783771688 0.944374701850713 GO:0008093 cytoskeletal anchor activity 1/1034 22/18639 0.0454545454545455 0.81936873571303 0.715305623558155 0.947321421968684 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/1034 22/18639 0.0454545454545455 0.81936873571303 0.715305623558155 0.947321421968684 GO:0140035 ubiquitin-like protein reader activity 1/1034 22/18639 0.0454545454545455 0.81936873571303 0.715305623558155 0.947321421968684 GO:0140784 metal ion sensor activity 1/1034 22/18639 0.0454545454545455 0.81936873571303 0.715305623558155 0.947321421968684 GO:0001653 peptide receptor activity 6/1034 128/18639 0.046875 0.844974008704062 0.720312680403557 0.952513622588895 GO:0051539 4 iron, 4 sulfur cluster binding 2/1034 45/18639 0.0444444444444444 0.801160541586074 0.721070331911438 0.952513622588895 GO:0016500 protein-hormone receptor activity 3/1034 67/18639 0.0447761194029851 0.80713935159791 0.726123860277467 0.954797237760466 GO:0004518 nuclease activity 10/1034 209/18639 0.0478468899521531 0.862493406013715 0.728907420379794 0.954797237760466 GO:0003887 DNA-directed DNA polymerase activity 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.954797237760466 GO:0005158 insulin receptor binding 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.954797237760466 GO:0005212 structural constituent of eye lens 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.954797237760466 GO:0005283 amino acid:sodium symporter activity 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.954797237760466 GO:0016917 GABA receptor activity 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.954797237760466 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.954797237760466 GO:0099186 structural constituent of postsynapse 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.954797237760466 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.955181057730635 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.955181057730635 GO:0004622 lysophospholipase activity 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.955181057730635 GO:0004806 triacylglycerol lipase activity 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.955181057730635 GO:0030552 cAMP binding 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.955181057730635 GO:0048027 mRNA 5'-UTR binding 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.955181057730635 GO:0070300 phosphatidic acid binding 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.955181057730635 GO:0005244 voltage-gated monoatomic ion channel activity 8/1034 173/18639 0.046242774566474 0.833577442112678 0.749995602881069 0.955181057730635 GO:0016782 transferase activity, transferring sulphur-containing groups 3/1034 70/18639 0.0428571428571429 0.772547665100857 0.753137809995796 0.955181057730635 GO:0061659 ubiquitin-like protein ligase activity 18/1034 372/18639 0.0483870967741935 0.87223123479129 0.758597898364137 0.955181057730635 GO:0051087 protein-folding chaperone binding 6/1034 134/18639 0.0447761194029851 0.80713935159791 0.759953875258135 0.955181057730635 GO:0008483 transaminase activity 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.955181057730635 GO:0015645 fatty acid ligase activity 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.955181057730635 GO:0015662 P-type ion transporter activity 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.955181057730635 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.955181057730635 GO:0017056 structural constituent of nuclear pore 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.955181057730635 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.955181057730635 GO:0019707 protein-cysteine S-acyltransferase activity 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.955181057730635 GO:0047617 fatty acyl-CoA hydrolase activity 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.955181057730635 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.955181057730635 GO:0120515 fatty acid-CoA ligase activity 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.955181057730635 GO:0140358 P-type transmembrane transporter activity 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.955181057730635 GO:0061630 ubiquitin protein ligase activity 17/1034 353/18639 0.0481586402266289 0.868113051435335 0.76041899304014 0.955181057730635 GO:0046873 metal ion transmembrane transporter activity 22/1034 450/18639 0.0488888888888889 0.881276595744681 0.760520854165515 0.955181057730635 GO:0022832 voltage-gated channel activity 8/1034 175/18639 0.0457142857142857 0.824050842774247 0.761147625557491 0.955181057730635 GO:0005004 GPI-linked ephrin receptor activity 2/1034 49/18639 0.0408163265306122 0.735759681048435 0.763774979366413 0.955181057730635 GO:0005008 hepatocyte growth factor receptor activity 2/1034 49/18639 0.0408163265306122 0.735759681048435 0.763774979366413 0.955181057730635 GO:0005009 insulin receptor activity 2/1034 49/18639 0.0408163265306122 0.735759681048435 0.763774979366413 0.955181057730635 GO:0005011 macrophage colony-stimulating factor receptor activity 2/1034 49/18639 0.0408163265306122 0.735759681048435 0.763774979366413 0.955181057730635 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/1034 49/18639 0.0408163265306122 0.735759681048435 0.763774979366413 0.955181057730635 GO:0005020 stem cell factor receptor activity 2/1034 49/18639 0.0408163265306122 0.735759681048435 0.763774979366413 0.955181057730635 GO:0008288 boss receptor activity 2/1034 49/18639 0.0408163265306122 0.735759681048435 0.763774979366413 0.955181057730635 GO:0036332 placental growth factor receptor activity 2/1034 49/18639 0.0408163265306122 0.735759681048435 0.763774979366413 0.955181057730635 GO:0038062 protein tyrosine kinase collagen receptor activity 2/1034 49/18639 0.0408163265306122 0.735759681048435 0.763774979366413 0.955181057730635 GO:0060175 brain-derived neurotrophic factor receptor activity 2/1034 49/18639 0.0408163265306122 0.735759681048435 0.763774979366413 0.955181057730635 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.955873336193641 GO:0004529 DNA exonuclease activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.955873336193641 GO:0008143 poly(A) binding 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.955873336193641 GO:0016289 acyl-CoA hydrolase activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.955873336193641 GO:0005006 epidermal growth factor receptor activity 2/1034 50/18639 0.04 0.721044487427466 0.773523363478875 0.955873336193641 GO:0005007 fibroblast growth factor receptor activity 2/1034 50/18639 0.04 0.721044487427466 0.773523363478875 0.955873336193641 GO:0005017 platelet-derived growth factor receptor activity 2/1034 50/18639 0.04 0.721044487427466 0.773523363478875 0.955873336193641 GO:0005019 platelet-derived growth factor beta-receptor activity 2/1034 50/18639 0.04 0.721044487427466 0.773523363478875 0.955873336193641 GO:0009055 electron transfer activity 5/1034 116/18639 0.0431034482758621 0.776987594210632 0.777782436960012 0.955873336193641 GO:0004521 RNA endonuclease activity 3/1034 73/18639 0.0410958904109589 0.74079913091863 0.777966342394833 0.955873336193641 GO:0004867 serine-type endopeptidase inhibitor activity 4/1034 95/18639 0.0421052631578947 0.75899419729207 0.779678971037717 0.955873336193641 GO:0005010 insulin-like growth factor receptor activity 2/1034 51/18639 0.0392156862745098 0.706906360223006 0.782918451196018 0.955873336193641 GO:0005021 vascular endothelial growth factor receptor activity 2/1034 51/18639 0.0392156862745098 0.706906360223006 0.782918451196018 0.955873336193641 GO:0005030 neurotrophin receptor activity 2/1034 51/18639 0.0392156862745098 0.706906360223006 0.782918451196018 0.955873336193641 GO:0005048 signal sequence binding 2/1034 51/18639 0.0392156862745098 0.706906360223006 0.782918451196018 0.955873336193641 GO:0016830 carbon-carbon lyase activity 2/1034 51/18639 0.0392156862745098 0.706906360223006 0.782918451196018 0.955873336193641 GO:0008266 poly(U) RNA binding 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.955873336193641 GO:0008320 protein transmembrane transporter activity 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.955873336193641 GO:0015252 proton channel activity 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.955873336193641 GO:0016405 CoA-ligase activity 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.955873336193641 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.955873336193641 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.955873336193641 GO:0035255 ionotropic glutamate receptor binding 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.955873336193641 GO:0016407 acetyltransferase activity 4/1034 96/18639 0.0416666666666667 0.751088007736944 0.786560342521846 0.955873336193641 GO:0016853 isomerase activity 8/1034 180/18639 0.0444444444444444 0.801160541586074 0.787461964279563 0.955873336193641 GO:0140767 enzyme-substrate adaptor activity 6/1034 139/18639 0.0431654676258993 0.778105561972086 0.78970451795234 0.957470383855361 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 2/1034 52/18639 0.0384615384615385 0.693312007141794 0.791969396061598 0.958410246998819 GO:0030594 neurotransmitter receptor activity 4/1034 97/18639 0.0412371134020619 0.74334483239945 0.79326912695428 0.958410246998819 GO:0005242 inward rectifier potassium channel activity 1/1034 28/18639 0.0357142857142857 0.643789720917381 0.797950411154769 0.958410246998819 GO:0019789 SUMO transferase activity 1/1034 28/18639 0.0357142857142857 0.643789720917381 0.797950411154769 0.958410246998819 GO:0050698 proteoglycan sulfotransferase activity 1/1034 28/18639 0.0357142857142857 0.643789720917381 0.797950411154769 0.958410246998819 GO:0097718 disordered domain specific binding 1/1034 28/18639 0.0357142857142857 0.643789720917381 0.797950411154769 0.958410246998819 GO:0005003 ephrin receptor activity 2/1034 53/18639 0.0377358490566038 0.680230648516478 0.800685424162615 0.958410246998819 GO:0005005 transmembrane-ephrin receptor activity 2/1034 53/18639 0.0377358490566038 0.680230648516478 0.800685424162615 0.958410246998819 GO:0005544 calcium-dependent phospholipid binding 2/1034 53/18639 0.0377358490566038 0.680230648516478 0.800685424162615 0.958410246998819 GO:0016860 intramolecular oxidoreductase activity 2/1034 53/18639 0.0377358490566038 0.680230648516478 0.800685424162615 0.958410246998819 GO:0017046 peptide hormone binding 2/1034 53/18639 0.0377358490566038 0.680230648516478 0.800685424162615 0.958410246998819 GO:0050661 NADP binding 2/1034 54/18639 0.037037037037037 0.667633784655061 0.809075797951114 0.962994008257343 GO:0004181 metallocarboxypeptidase activity 1/1034 29/18639 0.0344827586206897 0.621590075368505 0.809175991449539 0.962994008257343 GO:0005416 amino acid:monoatomic cation symporter activity 1/1034 29/18639 0.0344827586206897 0.621590075368505 0.809175991449539 0.962994008257343 GO:0016417 S-acyltransferase activity 1/1034 29/18639 0.0344827586206897 0.621590075368505 0.809175991449539 0.962994008257343 GO:0106222 lncRNA binding 1/1034 29/18639 0.0344827586206897 0.621590075368505 0.809175991449539 0.962994008257343 GO:0140713 histone chaperone activity 7/1034 164/18639 0.0426829268292683 0.769407227437845 0.810941680377606 0.963984759298121 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 5/1034 122/18639 0.040983606557377 0.738775089577322 0.813563749611699 0.965990061320558 GO:0098632 cell-cell adhesion mediator activity 2/1034 55/18639 0.0363636363636364 0.655494988570424 0.817149783849575 0.9678070330339 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/1034 30/18639 0.0333333333333333 0.600870406189555 0.819778464573729 0.9678070330339 GO:0008187 poly-pyrimidine tract binding 1/1034 30/18639 0.0333333333333333 0.600870406189555 0.819778464573729 0.9678070330339 GO:0016769 transferase activity, transferring nitrogenous groups 1/1034 30/18639 0.0333333333333333 0.600870406189555 0.819778464573729 0.9678070330339 GO:0098918 structural constituent of synapse 1/1034 30/18639 0.0333333333333333 0.600870406189555 0.819778464573729 0.9678070330339 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/1034 31/18639 0.032258064516129 0.58148748986086 0.829792386204702 0.97406310789711 GO:0005452 solute:inorganic anion antiporter activity 1/1034 31/18639 0.032258064516129 0.58148748986086 0.829792386204702 0.97406310789711 GO:0008327 methyl-CpG binding 1/1034 31/18639 0.032258064516129 0.58148748986086 0.829792386204702 0.97406310789711 GO:0016878 acid-thiol ligase activity 1/1034 31/18639 0.032258064516129 0.58148748986086 0.829792386204702 0.97406310789711 GO:0017147 Wnt-protein binding 1/1034 31/18639 0.032258064516129 0.58148748986086 0.829792386204702 0.97406310789711 GO:0015106 bicarbonate transmembrane transporter activity 1/1034 32/18639 0.03125 0.563316005802708 0.839250397418391 0.978493973513768 GO:0030515 snoRNA binding 1/1034 32/18639 0.03125 0.563316005802708 0.839250397418391 0.978493973513768 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/1034 32/18639 0.03125 0.563316005802708 0.839250397418391 0.978493973513768 GO:0047498 calcium-dependent phospholipase A2 activity 1/1034 32/18639 0.03125 0.563316005802708 0.839250397418391 0.978493973513768 GO:0070717 poly-purine tract binding 1/1034 32/18639 0.03125 0.563316005802708 0.839250397418391 0.978493973513768 GO:0140142 nucleocytoplasmic carrier activity 1/1034 32/18639 0.03125 0.563316005802708 0.839250397418391 0.978493973513768 GO:0030165 PDZ domain binding 3/1034 83/18639 0.036144578313253 0.651546223579036 0.846232107194656 0.979298549494999 GO:0004497 monooxygenase activity 4/1034 106/18639 0.0377358490566038 0.680230648516478 0.846263428021007 0.979298549494999 GO:0036002 pre-mRNA binding 2/1034 59/18639 0.0338983050847458 0.611054650362259 0.846465783741699 0.979298549494999 GO:0070063 RNA polymerase binding 2/1034 59/18639 0.0338983050847458 0.611054650362259 0.846465783741699 0.979298549494999 GO:0003713 transcription coactivator activity 11/1034 256/18639 0.04296875 0.774559507978723 0.846535556513532 0.979298549494999 GO:0042923 neuropeptide binding 1/1034 33/18639 0.0303030303030303 0.546245823808687 0.848183330673047 0.979298549494999 GO:0051117 ATPase binding 3/1034 84/18639 0.0357142857142857 0.643789720917381 0.851940044204479 0.979298549494999 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/1034 60/18639 0.0333333333333333 0.600870406189555 0.853095112592572 0.979298549494999 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/1034 60/18639 0.0333333333333333 0.600870406189555 0.853095112592572 0.979298549494999 GO:0140674 ATP-dependent histone chaperone activity 6/1034 152/18639 0.0394736842105263 0.711557059961315 0.853803103288629 0.979298549494999 GO:0005261 monoatomic cation channel activity 15/1034 341/18639 0.0439882697947214 0.7929374861739 0.855601406204081 0.979298549494999 GO:0008175 tRNA methyltransferase activity 1/1034 34/18639 0.0294117647058824 0.530179770167255 0.85662030993157 0.979298549494999 GO:0008376 acetylgalactosaminyltransferase activity 1/1034 34/18639 0.0294117647058824 0.530179770167255 0.85662030993157 0.979298549494999 GO:0016831 carboxy-lyase activity 1/1034 34/18639 0.0294117647058824 0.530179770167255 0.85662030993157 0.979298549494999 GO:0019825 oxygen binding 1/1034 34/18639 0.0294117647058824 0.530179770167255 0.85662030993157 0.979298549494999 GO:0030332 cyclin binding 1/1034 34/18639 0.0294117647058824 0.530179770167255 0.85662030993157 0.979298549494999 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/1034 34/18639 0.0294117647058824 0.530179770167255 0.85662030993157 0.979298549494999 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/1034 61/18639 0.0327868852459016 0.591020071661858 0.859462325073929 0.979298549494999 GO:0016836 hydro-lyase activity 2/1034 61/18639 0.0327868852459016 0.591020071661858 0.859462325073929 0.979298549494999 GO:0005506 iron ion binding 6/1034 154/18639 0.038961038961039 0.702316059182597 0.862080599916005 0.979298549494999 GO:0004175 endopeptidase activity 18/1034 405/18639 0.0444444444444444 0.801160541586074 0.863972190509661 0.979298549494999 GO:0000175 3'-5'-RNA exonuclease activity 1/1034 35/18639 0.0285714285714286 0.515031776733904 0.864588845246311 0.979298549494999 GO:0005343 organic acid:sodium symporter activity 1/1034 35/18639 0.0285714285714286 0.515031776733904 0.864588845246311 0.979298549494999 GO:0016229 steroid dehydrogenase activity 1/1034 35/18639 0.0285714285714286 0.515031776733904 0.864588845246311 0.979298549494999 GO:0034061 DNA polymerase activity 1/1034 35/18639 0.0285714285714286 0.515031776733904 0.864588845246311 0.979298549494999 GO:0140566 histone reader activity 1/1034 35/18639 0.0285714285714286 0.515031776733904 0.864588845246311 0.979298549494999 GO:0000993 RNA polymerase II complex binding 1/1034 36/18639 0.0277777777777778 0.500725338491296 0.872114922112324 0.983509513692173 GO:0004190 aspartic-type endopeptidase activity 1/1034 36/18639 0.0277777777777778 0.500725338491296 0.872114922112324 0.983509513692173 GO:0016409 palmitoyltransferase activity 1/1034 36/18639 0.0277777777777778 0.500725338491296 0.872114922112324 0.983509513692173 GO:0055106 ubiquitin-protein transferase regulator activity 1/1034 36/18639 0.0277777777777778 0.500725338491296 0.872114922112324 0.983509513692173 GO:0140658 ATP-dependent chromatin remodeler activity 6/1034 158/18639 0.0379746835443038 0.684535905785569 0.877473761576608 0.986142722814484 GO:0019213 deacetylase activity 1/1034 37/18639 0.027027027027027 0.487192221234774 0.879223085878161 0.986142722814484 GO:0022829 wide pore channel activity 1/1034 37/18639 0.027027027027027 0.487192221234774 0.879223085878161 0.986142722814484 GO:0030551 cyclic nucleotide binding 1/1034 37/18639 0.027027027027027 0.487192221234774 0.879223085878161 0.986142722814484 GO:0070001 aspartic-type peptidase activity 1/1034 37/18639 0.027027027027027 0.487192221234774 0.879223085878161 0.986142722814484 GO:0160215 deacylase activity 2/1034 65/18639 0.0307692307692308 0.554649605713435 0.882480594596268 0.988722835377381 GO:0005109 frizzled binding 1/1034 38/18639 0.0263157894736842 0.474371373307544 0.885936521487342 0.989503126921238 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/1034 38/18639 0.0263157894736842 0.474371373307544 0.885936521487342 0.989503126921238 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/1034 91/18639 0.032967032967033 0.594267434692967 0.886947050070713 0.989503126921238 GO:0016755 aminoacyltransferase activity 22/1034 496/18639 0.0443548387096774 0.799545298558682 0.887008611354372 0.989503126921238 GO:0140104 molecular carrier activity 10/1034 249/18639 0.0401606425702811 0.723940248421151 0.889915221022341 0.991674674558876 GO:0015294 solute:monoatomic cation symporter activity 4/1034 116/18639 0.0344827586206897 0.621590075368505 0.891223113704453 0.992061935836961 GO:0000217 DNA secondary structure binding 1/1034 39/18639 0.0256410256410256 0.462208004761196 0.892277128808566 0.992166064649352 GO:0004532 RNA exonuclease activity 1/1034 40/18639 0.025 0.450652804642166 0.898265593798455 0.992239925633008 GO:0002039 p53 binding 2/1034 69/18639 0.0289855072463768 0.522496005382222 0.901967331332791 0.992239925633008 GO:0008080 N-acetyltransferase activity 2/1034 69/18639 0.0289855072463768 0.522496005382222 0.901967331332791 0.992239925633008 GO:0140597 protein carrier chaperone 7/1034 188/18639 0.0372340425531915 0.67118502819046 0.902410415451931 0.992239925633008 GO:0008227 G protein-coupled amine receptor activity 1/1034 41/18639 0.024390243902439 0.439661272821626 0.903921455727182 0.992239925633008 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/1034 41/18639 0.024390243902439 0.439661272821626 0.903921455727182 0.992239925633008 GO:0051082 unfolded protein binding 4/1034 121/18639 0.0330578512396694 0.595904535064022 0.909045940081416 0.992239925633008 GO:0008307 structural constituent of muscle 1/1034 42/18639 0.0238095238095238 0.429193147278254 0.909263170684602 0.992239925633008 GO:0019894 kinesin binding 1/1034 42/18639 0.0238095238095238 0.429193147278254 0.909263170684602 0.992239925633008 GO:0031492 nucleosomal DNA binding 1/1034 42/18639 0.0238095238095238 0.429193147278254 0.909263170684602 0.992239925633008 GO:0043175 RNA polymerase core enzyme binding 1/1034 42/18639 0.0238095238095238 0.429193147278254 0.909263170684602 0.992239925633008 GO:0005201 extracellular matrix structural constituent 6/1034 168/18639 0.0357142857142857 0.643789720917381 0.909748635006648 0.992239925633008 GO:0008194 UDP-glycosyltransferase activity 5/1034 145/18639 0.0344827586206897 0.621590075368505 0.910052791644851 0.992239925633008 GO:0140299 molecular sensor activity 2/1034 71/18639 0.028169014084507 0.507777808047511 0.910538645829531 0.992239925633008 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/1034 122/18639 0.0327868852459016 0.591020071661858 0.912282624504119 0.992239925633008 GO:0015293 symporter activity 5/1034 146/18639 0.0342465753424658 0.617332609098858 0.913015343474642 0.992239925633008 GO:0004842 ubiquitin-protein transferase activity 19/1034 449/18639 0.0423162583518931 0.762797620329725 0.913946610403815 0.992239925633008 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/1034 43/18639 0.0232558139534884 0.419211911295038 0.914308171572494 0.992239925633008 GO:0008236 serine-type peptidase activity 7/1034 194/18639 0.0360824742268041 0.650426728349518 0.918262680705039 0.992239925633008 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/1034 73/18639 0.0273972602739726 0.493866087279086 0.918403705366879 0.992239925633008 GO:0016790 thiolester hydrolase activity 1/1034 44/18639 0.0227272727272727 0.409684367856515 0.919072924777164 0.992239925633008 GO:0019842 vitamin binding 5/1034 150/18639 0.0333333333333333 0.600870406189555 0.924024649876217 0.992239925633008 GO:0000510 H3-H4 histone complex chaperone activity 5/1034 151/18639 0.033112582781457 0.596891131976379 0.926576384956348 0.992239925633008 GO:0140584 chromatin extrusion motor activity 5/1034 151/18639 0.033112582781457 0.596891131976379 0.926576384956348 0.992239925633008 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/1034 151/18639 0.033112582781457 0.596891131976379 0.926576384956348 0.992239925633008 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/1034 151/18639 0.033112582781457 0.596891131976379 0.926576384956348 0.992239925633008 GO:0017171 serine hydrolase activity 7/1034 198/18639 0.0353535353535354 0.637286794443467 0.927549095302682 0.992239925633008 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/1034 46/18639 0.0217391304347826 0.391872004036666 0.927823039360876 0.992239925633008 GO:0019787 ubiquitin-like protein transferase activity 20/1034 479/18639 0.0417536534446764 0.752656041156019 0.9286527134194 0.992239925633008 GO:0051536 iron-sulfur cluster binding 2/1034 76/18639 0.0263157894736842 0.474371373307544 0.928990962836153 0.992239925633008 GO:0098631 cell adhesion mediator activity 2/1034 76/18639 0.0263157894736842 0.474371373307544 0.928990962836153 0.992239925633008 GO:0015616 DNA translocase activity 5/1034 152/18639 0.0328947368421053 0.592964216634429 0.929051666645726 0.992239925633008 GO:0016887 ATP hydrolysis activity 17/1034 417/18639 0.0407673860911271 0.734877475195859 0.929841442708898 0.992239925633008 GO:0004252 serine-type endopeptidase activity 6/1034 176/18639 0.0340909090909091 0.614526551784772 0.929998968387841 0.992239925633008 GO:0061775 cohesin loader activity 5/1034 153/18639 0.0326797385620915 0.589088633519172 0.931452348167526 0.992239925633008 GO:0061749 forked DNA-dependent helicase activity 1/1034 47/18639 0.0212765957446809 0.38353430182312 0.931836968113679 0.992239925633008 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/1034 47/18639 0.0212765957446809 0.38353430182312 0.931836968113679 0.992239925633008 GO:0003724 RNA helicase activity 2/1034 77/18639 0.025974025974026 0.468210706121731 0.932221786536384 0.992239925633008 GO:0051540 metal cluster binding 2/1034 77/18639 0.025974025974026 0.468210706121731 0.932221786536384 0.992239925633008 GO:0019199 transmembrane receptor protein kinase activity 2/1034 78/18639 0.0256410256410256 0.462208004761196 0.935313131997972 0.992239925633008 GO:0009378 four-way junction helicase activity 1/1034 48/18639 0.0208333333333333 0.375544003868472 0.935627876836272 0.992239925633008 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/1034 48/18639 0.0208333333333333 0.375544003868472 0.935627876836272 0.992239925633008 GO:0036121 double-stranded DNA helicase activity 1/1034 48/18639 0.0208333333333333 0.375544003868472 0.935627876836272 0.992239925633008 GO:0043138 3'-5' DNA helicase activity 1/1034 48/18639 0.0208333333333333 0.375544003868472 0.935627876836272 0.992239925633008 GO:0008186 ATP-dependent activity, acting on RNA 2/1034 79/18639 0.0253164556962025 0.456357270523713 0.938270512386051 0.992239925633008 GO:0016835 carbon-oxygen lyase activity 2/1034 79/18639 0.0253164556962025 0.456357270523713 0.938270512386051 0.992239925633008 GO:0060590 ATPase regulator activity 1/1034 49/18639 0.0204081632653061 0.367879840524217 0.939208145533561 0.992239925633008 GO:0005179 hormone activity 4/1034 132/18639 0.0303030303030303 0.546245823808687 0.939410113522828 0.992239925633008 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/1034 132/18639 0.0303030303030303 0.546245823808687 0.939410113522828 0.992239925633008 GO:0015605 organophosphate ester transmembrane transporter activity 1/1034 50/18639 0.02 0.360522243713733 0.942589467616309 0.9934424324253 GO:0004843 cysteine-type deubiquitinase activity 3/1034 108/18639 0.0277777777777778 0.500725338491296 0.943109802048599 0.9934424324253 GO:0003743 translation initiation factor activity 1/1034 51/18639 0.0196078431372549 0.353453180111503 0.945782887944715 0.9934424324253 GO:0005272 sodium channel activity 1/1034 51/18639 0.0196078431372549 0.353453180111503 0.945782887944715 0.9934424324253 GO:0008237 metallopeptidase activity 6/1034 184/18639 0.0326086956521739 0.587808006054999 0.946129360119791 0.9934424324253 GO:0003689 DNA clamp loader activity 5/1034 160/18639 0.03125 0.563316005802708 0.946318832048882 0.9934424324253 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/1034 53/18639 0.0188679245283019 0.340115324258239 0.951647173662171 0.998021858267028 GO:0015081 sodium ion transmembrane transporter activity 5/1034 164/18639 0.0304878048780488 0.549576591027032 0.953441147464119 0.998814921181773 GO:0017069 snRNA binding 1/1034 54/18639 0.0185185185185185 0.333816892327531 0.954337199618983 0.998814921181773 GO:0101005 deubiquitinase activity 3/1034 115/18639 0.0260869565217391 0.470246404844 0.957593820359876 0.999999994105172 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/1034 56/18639 0.0178571428571429 0.32189486045869 0.959276999754532 0.999999994105172 GO:0008408 3'-5' exonuclease activity 1/1034 58/18639 0.0172413793103448 0.310795037684253 0.96368287306283 0.999999994105172 GO:0017116 single-stranded DNA helicase activity 1/1034 58/18639 0.0172413793103448 0.310795037684253 0.96368287306283 0.999999994105172 GO:0016758 hexosyltransferase activity 6/1034 197/18639 0.0304568527918782 0.54901864524934 0.965341176295136 0.999999994105172 GO:0031593 polyubiquitin modification-dependent protein binding 1/1034 59/18639 0.0169491525423729 0.30552732518113 0.96570385736147 0.999999994105172 GO:0140030 modification-dependent protein binding 5/1034 173/18639 0.0289017341040462 0.520985901320424 0.966423292681005 0.999999994105172 GO:0003697 single-stranded DNA binding 3/1034 121/18639 0.0247933884297521 0.446928401298016 0.967180685124676 0.999999994105172 GO:0042393 histone binding 8/1034 247/18639 0.0323886639676113 0.583841690224669 0.967359636879483 0.999999994105172 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/1034 60/18639 0.0166666666666667 0.300435203094778 0.967612480154164 0.999999994105172 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/1034 60/18639 0.0166666666666667 0.300435203094778 0.967612480154164 0.999999994105172 GO:0016410 N-acyltransferase activity 2/1034 94/18639 0.0212765957446809 0.38353430182312 0.969778422128998 0.999999994105172 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 7/1034 229/18639 0.0305676855895196 0.551016529693478 0.973193212029342 0.999999994105172 GO:0019783 ubiquitin-like protein peptidase activity 3/1034 127/18639 0.0236220472440945 0.425813673677638 0.974695112620477 0.999999994105172 GO:0019843 rRNA binding 1/1034 65/18639 0.0153846153846154 0.277324802856718 0.975676890063989 0.999999994105172 GO:0008094 ATP-dependent activity, acting on DNA 6/1034 210/18639 0.0285714285714286 0.515031776733904 0.978086056296038 0.999999994105172 GO:0008173 RNA methyltransferase activity 1/1034 67/18639 0.0149253731343284 0.269046450532637 0.978309676970525 0.999999994105172 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/1034 67/18639 0.0149253731343284 0.269046450532637 0.978309676970525 0.999999994105172 GO:0140223 general transcription initiation factor activity 1/1034 68/18639 0.0147058823529412 0.265089885083627 0.979517290260019 0.999999994105172 GO:0098960 postsynaptic neurotransmitter receptor activity 1/1034 69/18639 0.0144927536231884 0.261248002691111 0.980657730832478 0.999999994105172 GO:0140097 catalytic activity, acting on DNA 11/1034 336/18639 0.0327380952380952 0.590140577507599 0.981399280073653 0.999999994105172 GO:0003678 DNA helicase activity 1/1034 74/18639 0.0135135135135135 0.243596110617387 0.985475981422689 0.999999994105172 GO:0003684 damaged DNA binding 1/1034 74/18639 0.0135135135135135 0.243596110617387 0.985475981422689 0.999999994105172 GO:0031491 nucleosome binding 1/1034 74/18639 0.0135135135135135 0.243596110617387 0.985475981422689 0.999999994105172 GO:0035064 methylated histone binding 1/1034 74/18639 0.0135135135135135 0.243596110617387 0.985475981422689 0.999999994105172 GO:0140034 methylation-dependent protein binding 1/1034 76/18639 0.0131578947368421 0.237185686653772 0.987048833453168 0.999999994105172 GO:0015370 solute:sodium symporter activity 1/1034 79/18639 0.0126582278481013 0.228178635261856 0.989094849168862 0.999999994105172 GO:0000049 tRNA binding 1/1034 80/18639 0.0125 0.225326402321083 0.989702388283054 0.999999994105172 GO:0043021 ribonucleoprotein complex binding 4/1034 177/18639 0.0225988700564972 0.407369766908173 0.990033331007706 0.999999994105172 GO:0008135 translation factor activity, RNA binding 1/1034 83/18639 0.0120481927710843 0.217182074526345 0.991329528112657 0.999999994105172 GO:0004527 exonuclease activity 1/1034 84/18639 0.0119047619047619 0.214596573639127 0.991812674692282 0.999999994105172 GO:0180051 translation factor activity 1/1034 84/18639 0.0119047619047619 0.214596573639127 0.991812674692282 0.999999994105172 GO:0004386 helicase activity 3/1034 155/18639 0.0193548387096774 0.348892493916516 0.99278880778903 0.999999994105172 GO:0008170 N-methyltransferase activity 1/1034 98/18639 0.0102040816326531 0.183939920262109 0.996332354773312 0.999999994105172 GO:0003730 mRNA 3'-UTR binding 6/1034 262/18639 0.0229007633587786 0.412811729443206 0.996965843756034 0.999999994105172 GO:0004222 metalloendopeptidase activity 1/1034 110/18639 0.00909090909090909 0.163873747142606 0.998158215101504 0.999999994105172 GO:0043022 ribosome binding 1/1034 112/18639 0.00892857142857143 0.160947430229345 0.998358044233161 0.999999994105172 GO:0016874 ligase activity 2/1034 167/18639 0.0119760479041916 0.215881583062116 0.999243071662671 0.999999994105172 GO:0140098 catalytic activity, acting on RNA 9/1034 387/18639 0.0232558139534884 0.419211911295038 0.999425188573688 0.999999994105172 GO:0003735 structural constituent of ribosome 2/1034 175/18639 0.0114285714285714 0.206012710693562 0.99950162512095 0.999999994105172 GO:0016741 transferase activity, transferring one-carbon groups 3/1034 215/18639 0.013953488372093 0.251527146777023 0.999586018991665 0.999999994105172 GO:0140101 catalytic activity, acting on a tRNA 1/1034 139/18639 0.00719424460431655 0.129684260328681 0.999652085213035 0.999999994105172 GO:0008168 methyltransferase activity 2/1034 204/18639 0.00980392156862745 0.176726590055752 0.999892113634742 0.999999994105172 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/1034 167/18639 0.00598802395209581 0.107940791531058 0.999930568685206 0.999999994105172 GO:0045182 translation regulator activity 3/1034 356/18639 0.00842696629213483 0.151905439767022 0.999999694637002 0.999999994105172 GO:0030371 translation repressor activity 1/1034 329/18639 0.00303951367781155 0.05479061454616 0.999999994105172 0.999999994105172