ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 51/442 175/18639 0.291428571428571 12.2894505494505 2.5584612408105e-41 1.77557210112248e-38 GO:0045296 cadherin binding 43/442 334/18639 0.12874251497006 5.42903107811526 1.11519925241681e-19 3.86974140588633e-17 GO:0009055 electron transfer activity 25/442 116/18639 0.21551724137931 9.08829380558589 2.6871477373539e-17 6.21626843241203e-15 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 19/442 68/18639 0.279411764705882 11.7827056161831 1.04615958293134e-15 1.81508687638587e-13 GO:0180051 translation factor activity 19/442 84/18639 0.226190476190476 9.53838073691015 7.27374529141235e-14 1.00959584644803e-11 GO:0022853 active monoatomic ion transmembrane transporter activity 21/442 118/18639 0.177966101694915 7.5047741391211 5.37152550688472e-13 6.21306450296333e-11 GO:0008135 translation factor activity, RNA binding 18/442 83/18639 0.216867469879518 9.14523251376547 7.23251182171019e-13 7.17051886323839e-11 GO:0015078 proton transmembrane transporter activity 25/442 185/18639 0.135135135135135 5.69860584566467 2.07761271487495e-12 1.80232903015402e-10 GO:0008137 NADH dehydrogenase (ubiquinone) activity 13/442 41/18639 0.317073170731707 13.37087517934 6.06437596553546e-12 4.67630768897957e-10 GO:0003743 translation initiation factor activity 14/442 51/18639 0.274509803921569 11.5759914825659 8.41793985648654e-12 5.84205026040166e-10 GO:0003954 NADH dehydrogenase activity 13/442 44/18639 0.295454545454545 12.4592245989305 1.6748011613192e-11 1.05664727814139e-09 GO:0019843 rRNA binding 15/442 65/18639 0.230769230769231 9.73146536721197 2.336173199519e-11 1.35108683372182e-09 GO:0015399 primary active transmembrane transporter activity 22/442 166/18639 0.132530120481928 5.58875320285668 6.59350827860343e-11 3.51991903488522e-09 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 13/442 58/18639 0.224137931034483 9.45182555780933 7.52726147798437e-10 3.73137104694368e-08 GO:0048027 mRNA 5'-UTR binding 8/442 24/18639 0.333333333333333 14.0565610859729 4.9476332155132e-08 2.28910496771077e-06 GO:0016651 oxidoreductase activity, acting on NAD(P)H 13/442 88/18639 0.147727272727273 6.22961229946524 1.50146482690038e-07 6.51260368668039e-06 GO:0044389 ubiquitin-like protein ligase binding 23/442 322/18639 0.0714285714285714 3.01212023270847 2.90442311708515e-06 0.000118568802544535 GO:0031625 ubiquitin protein ligase binding 22/442 302/18639 0.0728476821192053 3.07196368104042 3.47142512778305e-06 0.000133842724371191 GO:0043021 ribonucleoprotein complex binding 16/442 177/18639 0.0903954802259887 3.81194876907738 5.12539099855403e-06 0.00018721165015771 GO:0055105 ubiquitin-protein transferase inhibitor activity 5/442 15/18639 0.333333333333333 14.0565610859729 1.80891815496012e-05 0.000611771869959175 GO:0055106 ubiquitin-protein transferase regulator activity 7/442 36/18639 0.194444444444444 8.19966063348416 1.8511828918073e-05 0.000611771869959175 GO:0016853 isomerase activity 15/442 180/18639 0.0833333333333333 3.51414027149321 2.65808732037369e-05 0.000838505727426974 GO:0051082 unfolded protein binding 12/442 121/18639 0.0991735537190083 4.18211734789275 3.09076793454426e-05 0.000932605628945093 GO:0016860 intramolecular oxidoreductase activity 8/442 53/18639 0.150943396226415 6.36523520874242 3.26400923960555e-05 0.00094384267178594 GO:0022804 active transmembrane transporter activity 26/442 457/18639 0.0568927789934354 2.39915046981594 3.85342945138323e-05 0.00106971201570399 GO:0043024 ribosomal small subunit binding 5/442 20/18639 0.25 10.5424208144796 8.46698564128699e-05 0.00226003385963583 GO:1990948 ubiquitin ligase inhibitor activity 4/442 11/18639 0.363636363636364 15.3344302756067 9.01917093898101e-05 0.00231826097468623 GO:0003727 single-stranded RNA binding 9/442 89/18639 0.101123595505618 4.26434999237379 0.000259699313570978 0.00643683298636639 GO:0043022 ribosome binding 10/442 112/18639 0.0892857142857143 3.76515029088559 0.000333217966557868 0.00774505407828659 GO:0004129 cytochrome-c oxidase activity 4/442 15/18639 0.266666666666667 11.2452488687783 0.000345960628857182 0.00774505407828659 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 4/442 15/18639 0.266666666666667 11.2452488687783 0.000345960628857182 0.00774505407828659 GO:0061650 ubiquitin-like protein conjugating enzyme activity 6/442 41/18639 0.146341463414634 6.1711731596954 0.000382433935712145 0.00829403598075714 GO:0016675 oxidoreductase activity, acting on a heme group of donors 4/442 16/18639 0.25 10.5424208144796 0.000452680813220292 0.00952001467802675 GO:0003746 translation elongation factor activity 4/442 18/18639 0.222222222222222 9.3710407239819 0.000733019080104542 0.0149622129880162 GO:0016209 antioxidant activity 8/442 86/18639 0.0930232558139535 3.92276123329475 0.000990010847999283 0.0196305008146144 GO:0140517 protein-RNA adaptor activity 4/442 22/18639 0.181818181818182 7.66721513780337 0.0016256780530303 0.0313394602445285 GO:0017069 snRNA binding 6/442 54/18639 0.111111111111111 4.68552036199095 0.00169571384957109 0.0318060922054686 GO:0034713 type I transforming growth factor beta receptor binding 3/442 11/18639 0.272727272727273 11.5008227067051 0.00189636975455201 0.0326932301116697 GO:0070990 snRNP binding 3/442 11/18639 0.272727272727273 11.5008227067051 0.00189636975455201 0.0326932301116697 GO:0042162 telomeric DNA binding 5/442 38/18639 0.131578947368421 5.54864253393665 0.00193052435491884 0.0326932301116697 GO:0008171 O-methyltransferase activity 4/442 23/18639 0.173913043478261 7.33385795789888 0.00193144443022832 0.0326932301116697 GO:0004601 peroxidase activity 6/442 57/18639 0.105263157894737 4.43891402714932 0.00224490401075426 0.0370943662729395 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 6/442 59/18639 0.101694915254237 4.28844236521206 0.00267910767553265 0.0423408345215045 GO:0016835 carbon-oxygen lyase activity 7/442 79/18639 0.0886075949367089 3.73655421272696 0.00268443331260259 0.0423408345215045 GO:0051117 ATPase binding 7/442 84/18639 0.0833333333333333 3.51414027149321 0.00379296163486724 0.0584958972132859 GO:0032036 myosin heavy chain binding 3/442 14/18639 0.214285714285714 9.0363606981254 0.00396793186089099 0.0598640154664857 GO:0004857 enzyme inhibitor activity 19/442 416/18639 0.0456730769230769 1.9260191872607 0.00515488322185869 0.0761167862972326 GO:0008142 oxysterol binding 3/442 16/18639 0.1875 7.90681561085973 0.00589359632790233 0.080707034709396 GO:0017070 U6 snRNA binding 3/442 16/18639 0.1875 7.90681561085973 0.00589359632790233 0.080707034709396 GO:0043023 ribosomal large subunit binding 3/442 16/18639 0.1875 7.90681561085973 0.00589359632790233 0.080707034709396 GO:0060590 ATPase regulator activity 5/442 49/18639 0.102040816326531 4.30302890386924 0.00593092041812564 0.080707034709396 GO:1990381 ubiquitin-specific protease binding 3/442 18/18639 0.166666666666667 7.02828054298643 0.00829182352786392 0.11066395246803 GO:0003925 G protein activity 5/442 54/18639 0.0925925925925926 3.90460030165913 0.0089356739697134 0.117006749716625 GO:0061631 ubiquitin conjugating enzyme activity 4/442 35/18639 0.114285714285714 4.81939237233355 0.00913510333648563 0.117402994731871 GO:0070003 threonine-type peptidase activity 3/442 19/18639 0.157894736842105 6.65837104072398 0.00967568632862478 0.120715109433592 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 4/442 36/18639 0.111111111111111 4.68552036199095 0.0100885826327786 0.120715109433592 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 4/442 36/18639 0.111111111111111 4.68552036199095 0.0100885826327786 0.120715109433592 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 4/442 36/18639 0.111111111111111 4.68552036199095 0.0100885826327786 0.120715109433592 GO:0016504 peptidase activator activity 5/442 57/18639 0.087719298245614 3.69909502262443 0.0111700463152178 0.131390036317985 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 4/442 39/18639 0.102564102564103 4.32509571876088 0.0133276921941757 0.154156973045966 GO:0015036 disulfide oxidoreductase activity 4/442 40/18639 0.1 4.21696832579186 0.0145380299479706 0.16334230894429 GO:0070034 telomerase RNA binding 3/442 22/18639 0.136363636363636 5.75041135335253 0.0145925405685101 0.16334230894429 GO:0044325 transmembrane transporter binding 8/442 136/18639 0.0588235294117647 2.48056960340697 0.0158868380848098 0.175007390966 GO:0004602 glutathione peroxidase activity 3/442 23/18639 0.130434782608696 5.50039346842416 0.0164917049892523 0.178831925977205 GO:0016859 cis-trans isomerase activity 4/442 42/18639 0.0952380952380952 4.01616031027796 0.017161750510396 0.182297989903166 GO:0005200 structural constituent of cytoskeleton 7/442 112/18639 0.0625 2.63560520361991 0.0173366964461224 0.182297989903166 GO:0003779 actin binding 18/442 443/18639 0.0406320541760722 1.71344085472355 0.0192764460083893 0.197915200719147 GO:0061134 peptidase regulator activity 11/442 226/18639 0.0486725663716814 2.05250670724382 0.0193922675056224 0.197915200719147 GO:0001094 TFIID-class transcription factor complex binding 2/442 10/18639 0.2 8.43393665158371 0.0222595345046276 0.220687384945879 GO:0097177 mitochondrial ribosome binding 2/442 10/18639 0.2 8.43393665158371 0.0222595345046276 0.220687384945879 GO:0005160 transforming growth factor beta receptor binding 3/442 26/18639 0.115384615384615 4.86573268360599 0.022982091473002 0.224641851862865 GO:0097110 scaffold protein binding 5/442 70/18639 0.0714285714285714 3.01212023270847 0.0252056322325799 0.235298347663866 GO:0003697 single-stranded DNA binding 7/442 121/18639 0.0578512396694215 2.43956845293744 0.0252794700255634 0.235298347663866 GO:0001671 ATPase activator activity 3/442 27/18639 0.111111111111111 4.68552036199095 0.0254107916997812 0.235298347663866 GO:0015217 ADP transmembrane transporter activity 2/442 11/18639 0.181818181818182 7.66721513780337 0.0267846822268666 0.235298347663866 GO:0034511 U3 snoRNA binding 2/442 11/18639 0.181818181818182 7.66721513780337 0.0267846822268666 0.235298347663866 GO:0042608 T cell receptor binding 2/442 11/18639 0.181818181818182 7.66721513780337 0.0267846822268666 0.235298347663866 GO:0048185 activin binding 2/442 11/18639 0.181818181818182 7.66721513780337 0.0267846822268666 0.235298347663866 GO:0070697 activin receptor binding 2/442 11/18639 0.181818181818182 7.66721513780337 0.0267846822268666 0.235298347663866 GO:0051015 actin filament binding 10/442 209/18639 0.0478468899521531 2.01768819415878 0.027817058784506 0.23673795290571 GO:0046625 sphingolipid binding 3/442 28/18639 0.107142857142857 4.5181803490627 0.0279719195075911 0.23673795290571 GO:0097718 disordered domain specific binding 3/442 28/18639 0.107142857142857 4.5181803490627 0.0279719195075911 0.23673795290571 GO:0005049 nuclear export signal receptor activity 2/442 12/18639 0.166666666666667 7.02828054298643 0.0316447705589093 0.264596033347989 GO:0031210 phosphatidylcholine binding 3/442 30/18639 0.1 4.21696832579186 0.0334893289686847 0.276685646479371 GO:0017022 myosin binding 5/442 76/18639 0.0657894736842105 2.77432126696833 0.0343471478375975 0.280434359991678 GO:0019855 calcium channel inhibitor activity 2/442 13/18639 0.153846153846154 6.48764357814132 0.0368214452683405 0.293725092140555 GO:0140666 annealing activity 2/442 13/18639 0.153846153846154 6.48764357814132 0.0368214452683405 0.293725092140555 GO:0015485 cholesterol binding 4/442 54/18639 0.0740740740740741 3.1236802413273 0.0389335726592894 0.29817823197748 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/442 54/18639 0.0740740740740741 3.1236802413273 0.0389335726592894 0.29817823197748 GO:0030515 snoRNA binding 3/442 32/18639 0.09375 3.95340780542986 0.0395279500604153 0.29817823197748 GO:0031369 translation initiation factor binding 3/442 32/18639 0.09375 3.95340780542986 0.0395279500604153 0.29817823197748 GO:0140142 nucleocytoplasmic carrier activity 3/442 32/18639 0.09375 3.95340780542986 0.0395279500604153 0.29817823197748 GO:0015631 tubulin binding 15/442 385/18639 0.038961038961039 1.64297467238644 0.0420891071836852 0.312278078727198 GO:0005347 ATP transmembrane transporter activity 2/442 14/18639 0.142857142857143 6.02424046541694 0.0422970308362488 0.312278078727198 GO:0015035 protein-disulfide reductase activity 3/442 34/18639 0.0882352941176471 3.72085440511046 0.0460783459335235 0.333498290434552 GO:0000774 adenyl-nucleotide exchange factor activity 2/442 15/18639 0.133333333333333 5.62262443438914 0.0480545087081487 0.333498290434552 GO:0031386 protein tag activity 2/442 15/18639 0.133333333333333 5.62262443438914 0.0480545087081487 0.333498290434552 GO:0033130 acetylcholine receptor binding 2/442 15/18639 0.133333333333333 5.62262443438914 0.0480545087081487 0.333498290434552 GO:0051371 muscle alpha-actinin binding 2/442 15/18639 0.133333333333333 5.62262443438914 0.0480545087081487 0.333498290434552 GO:0141047 molecular tag activity 2/442 15/18639 0.133333333333333 5.62262443438914 0.0480545087081487 0.333498290434552 GO:0016829 lyase activity 9/442 200/18639 0.045 1.89763574660633 0.0494783500432847 0.339979949802372 GO:0031593 polyubiquitin modification-dependent protein binding 4/442 59/18639 0.0677966101694915 2.85896157680804 0.0511719900209846 0.348170206613366 GO:0020037 heme binding 7/442 142/18639 0.0492957746478873 2.07878720285514 0.0526510090141792 0.353549455414034 GO:0003924 GTPase activity 13/442 331/18639 0.0392749244712991 1.65621112493336 0.0529814745865411 0.353549455414034 GO:0016722 oxidoreductase activity, acting on metal ions 2/442 16/18639 0.125 5.27121040723982 0.0540774961910411 0.354054550533797 GO:0097027 ubiquitin-protein transferase activator activity 2/442 16/18639 0.125 5.27121040723982 0.0540774961910411 0.354054550533797 GO:0042805 actinin binding 3/442 37/18639 0.0810810810810811 3.4191635073988 0.0568364443921351 0.368640115963942 GO:0016018 cyclosporin A binding 2/442 17/18639 0.117647058823529 4.96113920681395 0.0603502259783038 0.387806081749471 GO:0005507 copper ion binding 4/442 63/18639 0.0634920634920635 2.67744020685197 0.0623062240931812 0.39670201395108 GO:0008308 voltage-gated monoatomic anion channel activity 2/442 18/18639 0.111111111111111 4.68552036199095 0.0668575262846087 0.400468830761126 GO:0031690 adrenergic receptor binding 2/442 18/18639 0.111111111111111 4.68552036199095 0.0668575262846087 0.400468830761126 GO:0070628 proteasome binding 2/442 18/18639 0.111111111111111 4.68552036199095 0.0668575262846087 0.400468830761126 GO:0098641 cadherin binding involved in cell-cell adhesion 2/442 18/18639 0.111111111111111 4.68552036199095 0.0668575262846087 0.400468830761126 GO:0005525 GTP binding 14/442 378/18639 0.037037037037037 1.56184012066365 0.0676228918499648 0.400468830761126 GO:0043178 alcohol binding 5/442 92/18639 0.0543478260869565 2.2918306118434 0.0677202191189742 0.400468830761126 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/442 40/18639 0.075 3.16272624434389 0.0686682865426138 0.400468830761126 GO:0050997 quaternary ammonium group binding 3/442 40/18639 0.075 3.16272624434389 0.0686682865426138 0.400468830761126 GO:0061791 GTPase motor activity 3/442 40/18639 0.075 3.16272624434389 0.0686682865426138 0.400468830761126 GO:1990606 membrane scission GTPase motor activity 3/442 40/18639 0.075 3.16272624434389 0.0686682865426138 0.400468830761126 GO:0051219 phosphoprotein binding 5/442 93/18639 0.0537634408602151 2.26718727193111 0.0702467186381179 0.404090349624472 GO:0046906 tetrapyrrole binding 7/442 152/18639 0.0460526315789474 1.94202488687783 0.0704537929460535 0.404090349624472 GO:0003756 protein disulfide isomerase activity 2/442 19/18639 0.105263157894737 4.43891402714932 0.073584801573548 0.405300415016209 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/442 19/18639 0.105263157894737 4.43891402714932 0.073584801573548 0.405300415016209 GO:0008301 DNA binding, bending 2/442 19/18639 0.105263157894737 4.43891402714932 0.073584801573548 0.405300415016209 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/442 19/18639 0.105263157894737 4.43891402714932 0.073584801573548 0.405300415016209 GO:0097001 ceramide binding 2/442 19/18639 0.105263157894737 4.43891402714932 0.073584801573548 0.405300415016209 GO:0005506 iron ion binding 7/442 154/18639 0.0454545454545455 1.91680378445084 0.0743966736945264 0.406545602708672 GO:0008307 structural constituent of muscle 3/442 42/18639 0.0714285714285714 3.01212023270847 0.0771238684487704 0.418155974245677 GO:0032934 sterol binding 4/442 68/18639 0.0588235294117647 2.48056960340697 0.0778620461880921 0.418885736856868 GO:0000339 RNA cap binding 2/442 20/18639 0.1 4.21696832579186 0.0805180138611284 0.425348256246429 GO:0042288 MHC class I protein binding 2/442 20/18639 0.1 4.21696832579186 0.0805180138611284 0.425348256246429 GO:0019207 kinase regulator activity 11/442 287/18639 0.0383275261324042 1.61625963706308 0.0812161151563861 0.425348256246429 GO:0008200 ion channel inhibitor activity 3/442 43/18639 0.0697674418604651 2.94207092497106 0.0815148675515492 0.425348256246429 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 6/442 128/18639 0.046875 1.97670390271493 0.0843852739460864 0.437040150138686 GO:0016248 channel inhibitor activity 3/442 44/18639 0.0681818181818182 2.87520567667626 0.086011345866442 0.440758718968523 GO:0001846 opsonin binding 2/442 21/18639 0.0952380952380952 4.01616031027796 0.0876436645787553 0.440758718968523 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/442 21/18639 0.0952380952380952 4.01616031027796 0.0876436645787553 0.440758718968523 GO:0051428 peptide hormone receptor binding 2/442 21/18639 0.0952380952380952 4.01616031027796 0.0876436645787553 0.440758718968523 GO:0043130 ubiquitin binding 5/442 100/18639 0.05 2.10848416289593 0.0893558585966742 0.446136445079798 GO:0141110 transporter inhibitor activity 3/442 45/18639 0.0666666666666667 2.81131221719457 0.0906107320974416 0.449170343397318 GO:0061133 endopeptidase activator activity 2/442 22/18639 0.0909090909090909 3.83360756890169 0.0949487769797798 0.462886392853615 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3/442 46/18639 0.0652173913043478 2.75019673421208 0.0953104021161161 0.462886392853615 GO:0019001 guanyl nucleotide binding 14/442 400/18639 0.035 1.47593891402715 0.09604559160075 0.462886392853615 GO:0032561 guanyl ribonucleotide binding 14/442 400/18639 0.035 1.47593891402715 0.09604559160075 0.462886392853615 GO:0003684 damaged DNA binding 4/442 74/18639 0.0540540540540541 2.27944233826587 0.0988235965517282 0.470438776384481 GO:0051087 protein-folding chaperone binding 6/442 134/18639 0.0447761194029851 1.88819477274262 0.0996593551903823 0.470438776384481 GO:0043495 protein-membrane adaptor activity 3/442 47/18639 0.0638297872340425 2.69168191007991 0.100107685597527 0.470438776384481 GO:0000295 adenine nucleotide transmembrane transporter activity 2/442 23/18639 0.0869565217391304 3.66692897894944 0.102420879074116 0.470438776384481 GO:0031681 G-protein beta-subunit binding 2/442 23/18639 0.0869565217391304 3.66692897894944 0.102420879074116 0.470438776384481 GO:0019003 GDP binding 4/442 75/18639 0.0533333333333333 2.24904977375566 0.102548919869233 0.470438776384481 GO:0044183 protein folding chaperone 4/442 75/18639 0.0533333333333333 2.24904977375566 0.102548919869233 0.470438776384481 GO:0002020 protease binding 6/442 136/18639 0.0441176470588235 1.86042720255523 0.105054852078432 0.470438776384481 GO:0016247 channel regulator activity 7/442 168/18639 0.0416666666666667 1.75707013574661 0.105544410461767 0.470438776384481 GO:0016763 pentosyltransferase activity 3/442 49/18639 0.0612244897959184 2.58181734232154 0.109984218070034 0.470438776384481 GO:0035254 glutamate receptor binding 3/442 49/18639 0.0612244897959184 2.58181734232154 0.109984218070034 0.470438776384481 GO:0001091 RNA polymerase II general transcription initiation factor binding 2/442 24/18639 0.0833333333333333 3.51414027149321 0.110047987075866 0.470438776384481 GO:0015295 solute:proton symporter activity 2/442 24/18639 0.0833333333333333 3.51414027149321 0.110047987075866 0.470438776384481 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/442 24/18639 0.0833333333333333 3.51414027149321 0.110047987075866 0.470438776384481 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/442 24/18639 0.0833333333333333 3.51414027149321 0.110047987075866 0.470438776384481 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/442 24/18639 0.0833333333333333 3.51414027149321 0.110047987075866 0.470438776384481 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/442 24/18639 0.0833333333333333 3.51414027149321 0.110047987075866 0.470438776384481 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/442 24/18639 0.0833333333333333 3.51414027149321 0.110047987075866 0.470438776384481 GO:0141108 transporter regulator activity 7/442 170/18639 0.0411764705882353 1.73639872238488 0.110492104539871 0.470438776384481 GO:0001848 complement binding 2/442 25/18639 0.08 3.37357466063348 0.11781858934931 0.495552127323765 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/442 25/18639 0.08 3.37357466063348 0.11781858934931 0.495552127323765 GO:0005048 signal sequence binding 3/442 51/18639 0.0588235294117647 2.48056960340697 0.120218273778153 0.499347230530464 GO:0030544 Hsp70 protein binding 3/442 51/18639 0.0588235294117647 2.48056960340697 0.120218273778153 0.499347230530464 GO:0000049 tRNA binding 4/442 80/18639 0.05 2.10848416289593 0.122109490477819 0.499347230530464 GO:0048306 calcium-dependent protein binding 4/442 80/18639 0.05 2.10848416289593 0.122109490477819 0.499347230530464 GO:0008017 microtubule binding 10/442 276/18639 0.036231884057971 1.52788707456227 0.122318485864811 0.499347230530464 GO:0008198 ferrous iron binding 2/442 26/18639 0.0769230769230769 3.24382178907066 0.125721630839003 0.50144144713947 GO:0015216 purine nucleotide transmembrane transporter activity 2/442 26/18639 0.0769230769230769 3.24382178907066 0.125721630839003 0.50144144713947 GO:0050681 nuclear androgen receptor binding 2/442 26/18639 0.0769230769230769 3.24382178907066 0.125721630839003 0.50144144713947 GO:0097602 cullin family protein binding 2/442 26/18639 0.0769230769230769 3.24382178907066 0.125721630839003 0.50144144713947 GO:0051020 GTPase binding 11/442 315/18639 0.0349206349206349 1.47259211376858 0.13074718215304 0.515667053284874 GO:0005246 calcium channel regulator activity 3/442 53/18639 0.0566037735849057 2.38696320327841 0.130787426961109 0.515667053284874 GO:0008266 poly(U) RNA binding 2/442 27/18639 0.0740740740740741 3.1236802413273 0.13374649797014 0.515667053284874 GO:0008320 protein transmembrane transporter activity 2/442 27/18639 0.0740740740740741 3.1236802413273 0.13374649797014 0.515667053284874 GO:0008395 steroid hydroxylase activity 2/442 27/18639 0.0740740740740741 3.1236802413273 0.13374649797014 0.515667053284874 GO:0035255 ionotropic glutamate receptor binding 2/442 27/18639 0.0740740740740741 3.1236802413273 0.13374649797014 0.515667053284874 GO:0004860 protein kinase inhibitor activity 4/442 84/18639 0.0476190476190476 2.00808015513898 0.138812488433548 0.532242358966199 GO:0140313 molecular sequestering activity 3/442 55/18639 0.0545454545454545 2.30016454134101 0.141669038782729 0.532252998810651 GO:0016866 intramolecular transferase activity 2/442 28/18639 0.0714285714285714 3.01212023270847 0.141883004005721 0.532252998810651 GO:0051393 alpha-actinin binding 2/442 28/18639 0.0714285714285714 3.01212023270847 0.141883004005721 0.532252998810651 GO:0051537 2 iron, 2 sulfur cluster binding 2/442 28/18639 0.0714285714285714 3.01212023270847 0.141883004005721 0.532252998810651 GO:0061135 endopeptidase regulator activity 7/442 184/18639 0.0380434782608696 1.60428142829038 0.148426715601811 0.553807207675574 GO:0019887 protein kinase regulator activity 9/442 255/18639 0.0352941176470588 1.48834176204418 0.153749661907069 0.567104046837359 GO:0003713 transcription coactivator activity 9/442 256/18639 0.03515625 1.4825279270362 0.156257177362239 0.567104046837359 GO:0032182 ubiquitin-like protein binding 5/442 120/18639 0.0416666666666667 1.75707013574661 0.156677268934851 0.567104046837359 GO:0001965 G-protein alpha-subunit binding 2/442 30/18639 0.0666666666666667 2.81131221719457 0.158452235267308 0.567104046837359 GO:0008187 poly-pyrimidine tract binding 2/442 30/18639 0.0666666666666667 2.81131221719457 0.158452235267308 0.567104046837359 GO:0015215 nucleotide transmembrane transporter activity 2/442 30/18639 0.0666666666666667 2.81131221719457 0.158452235267308 0.567104046837359 GO:0033612 receptor serine/threonine kinase binding 2/442 30/18639 0.0666666666666667 2.81131221719457 0.158452235267308 0.567104046837359 GO:0061980 regulatory RNA binding 3/442 58/18639 0.0517241379310345 2.18119051334061 0.158527644216783 0.567104046837359 GO:0070063 RNA polymerase binding 3/442 59/18639 0.0508474576271186 2.14422118260603 0.164278839977272 0.584664179201165 GO:0019210 kinase inhibitor activity 4/442 90/18639 0.0444444444444444 1.87420814479638 0.165445806994923 0.585813214563655 GO:0008327 methyl-CpG binding 2/442 31/18639 0.0645161290322581 2.72062472631733 0.166866595558452 0.587844757957188 GO:0022884 macromolecule transmembrane transporter activity 2/442 32/18639 0.0625 2.63560520361991 0.175355838591655 0.60754992455208 GO:0051059 NF-kappaB binding 2/442 32/18639 0.0625 2.63560520361991 0.175355838591655 0.60754992455208 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 3/442 61/18639 0.0491803278688525 2.07391884875009 0.175961865756438 0.60754992455208 GO:0016836 hydro-lyase activity 3/442 61/18639 0.0491803278688525 2.07391884875009 0.175961865756438 0.60754992455208 GO:0000287 magnesium ion binding 8/442 230/18639 0.0347826086956522 1.46677159157978 0.18141787026899 0.623287138448906 GO:0004867 serine-type endopeptidase inhibitor activity 4/442 95/18639 0.0421052631578947 1.77556561085973 0.188912795996502 0.636997871530411 GO:0008276 protein methyltransferase activity 4/442 95/18639 0.0421052631578947 1.77556561085973 0.188912795996502 0.636997871530411 GO:0051427 hormone receptor binding 2/442 34/18639 0.0588235294117647 2.48056960340697 0.192526292350688 0.636997871530411 GO:0003712 transcription coregulator activity 15/442 495/18639 0.0303030303030303 1.2778691896339 0.19978782267649 0.636997871530411 GO:0031072 heat shock protein binding 5/442 131/18639 0.0381679389312977 1.6095298953404 0.200489155357737 0.636997871530411 GO:0043015 gamma-tubulin binding 2/442 35/18639 0.0571428571428571 2.40969618616677 0.201192020679396 0.636997871530411 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/442 36/18639 0.0555555555555556 2.34276018099548 0.209901643732777 0.636997871530411 GO:0045505 dynein intermediate chain binding 2/442 36/18639 0.0555555555555556 2.34276018099548 0.209901643732777 0.636997871530411 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0005345 purine nucleobase transmembrane transporter activity 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0005522 profilin binding 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0005528 FK506 binding 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0016868 intramolecular phosphotransferase activity 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0030957 Tat protein binding 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0031996 thioesterase binding 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0032356 oxidized DNA binding 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0043208 glycosphingolipid binding 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0050815 phosphoserine residue binding 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0051880 G-quadruplex DNA binding 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0098505 G-rich strand telomeric DNA binding 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0140940 histone H2A methyltransferase activity 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:1905394 retromer complex binding 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:1990259 histone H2AQ104 methyltransferase activity 1/442 10/18639 0.1 4.21696832579186 0.213413677174901 0.636997871530411 GO:0030414 peptidase inhibitor activity 6/442 169/18639 0.0355029585798817 1.49714851803261 0.213446374135133 0.636997871530411 GO:0022829 wide pore channel activity 2/442 37/18639 0.0540540540540541 2.27944233826587 0.218648226552242 0.636997871530411 GO:0005253 monoatomic anion channel activity 4/442 103/18639 0.0388349514563107 1.63765760224926 0.228432144546828 0.636997871530411 GO:0140030 modification-dependent protein binding 6/442 173/18639 0.0346820809248555 1.46253236732666 0.228645825478401 0.636997871530411 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/442 11/18639 0.0909090909090909 3.83360756890169 0.232076576669705 0.636997871530411 GO:0005114 type II transforming growth factor beta receptor binding 1/442 11/18639 0.0909090909090909 3.83360756890169 0.232076576669705 0.636997871530411 GO:0005536 D-glucose binding 1/442 11/18639 0.0909090909090909 3.83360756890169 0.232076576669705 0.636997871530411 GO:0008199 ferric iron binding 1/442 11/18639 0.0909090909090909 3.83360756890169 0.232076576669705 0.636997871530411 GO:0008526 phosphatidylinositol transfer activity 1/442 11/18639 0.0909090909090909 3.83360756890169 0.232076576669705 0.636997871530411 GO:0010854 adenylate cyclase regulator activity 1/442 11/18639 0.0909090909090909 3.83360756890169 0.232076576669705 0.636997871530411 GO:0015205 nucleobase transmembrane transporter activity 1/442 11/18639 0.0909090909090909 3.83360756890169 0.232076576669705 0.636997871530411 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/442 11/18639 0.0909090909090909 3.83360756890169 0.232076576669705 0.636997871530411 GO:0032050 clathrin heavy chain binding 1/442 11/18639 0.0909090909090909 3.83360756890169 0.232076576669705 0.636997871530411 GO:0050786 RAGE receptor binding 1/442 11/18639 0.0909090909090909 3.83360756890169 0.232076576669705 0.636997871530411 GO:0050998 nitric-oxide synthase binding 1/442 11/18639 0.0909090909090909 3.83360756890169 0.232076576669705 0.636997871530411 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/442 11/18639 0.0909090909090909 3.83360756890169 0.232076576669705 0.636997871530411 GO:0140031 phosphorylation-dependent protein binding 1/442 11/18639 0.0909090909090909 3.83360756890169 0.232076576669705 0.636997871530411 GO:0000217 DNA secondary structure binding 2/442 39/18639 0.0512820512820513 2.16254785938044 0.236226035365123 0.636997871530411 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/442 39/18639 0.0512820512820513 2.16254785938044 0.236226035365123 0.636997871530411 GO:0004497 monooxygenase activity 4/442 106/18639 0.0377358490566038 1.59130880218561 0.243760585671273 0.636997871530411 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/442 40/18639 0.05 2.10848416289593 0.245044864250518 0.636997871530411 GO:0140662 ATP-dependent protein folding chaperone 2/442 40/18639 0.05 2.10848416289593 0.245044864250518 0.636997871530411 GO:0000340 RNA 7-methylguanosine cap binding 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0003720 telomerase activity 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0003995 acyl-CoA dehydrogenase activity 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0004032 aldose reductase (NADPH) activity 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0004300 enoyl-CoA hydratase activity 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0004859 phospholipase inhibitor activity 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0005527 macrolide binding 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0008179 adenylate cyclase binding 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0010853 cyclase activator activity 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0016208 AMP binding 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0034452 dynactin binding 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0035197 siRNA binding 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0036009 protein-glutamine N-methyltransferase activity 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0042301 phosphate ion binding 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0043047 single-stranded telomeric DNA binding 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0070008 serine-type exopeptidase activity 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0070679 inositol 1,4,5 trisphosphate binding 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0097371 MDM2/MDM4 family protein binding 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0097677 STAT family protein binding 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/442 12/18639 0.0833333333333333 3.51414027149321 0.250297649952504 0.636997871530411 GO:0042287 MHC protein binding 2/442 41/18639 0.0487804878048781 2.05705771989847 0.253875838826206 0.636997871530411 GO:0140318 protein transporter activity 2/442 41/18639 0.0487804878048781 2.05705771989847 0.253875838826206 0.636997871530411 GO:0005496 steroid binding 4/442 108/18639 0.037037037037037 1.56184012066365 0.254105108540069 0.636997871530411 GO:0048029 monosaccharide binding 3/442 74/18639 0.0405405405405405 1.7095817536994 0.256364889010647 0.636997871530411 GO:0031492 nucleosomal DNA binding 2/442 42/18639 0.0476190476190476 2.00808015513898 0.262713437345078 0.636997871530411 GO:0035198 miRNA binding 2/442 42/18639 0.0476190476190476 2.00808015513898 0.262713437345078 0.636997871530411 GO:0051879 Hsp90 protein binding 2/442 42/18639 0.0476190476190476 2.00808015513898 0.262713437345078 0.636997871530411 GO:0003725 double-stranded RNA binding 3/442 75/18639 0.04 1.68678733031674 0.262773887724873 0.636997871530411 GO:0004222 metalloendopeptidase activity 4/442 110/18639 0.0363636363636364 1.53344302756067 0.264537975388728 0.636997871530411 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/442 13/18639 0.0769230769230769 3.24382178907066 0.268087333676184 0.636997871530411 GO:0003964 RNA-directed DNA polymerase activity 1/442 13/18639 0.0769230769230769 3.24382178907066 0.268087333676184 0.636997871530411 GO:0030955 potassium ion binding 1/442 13/18639 0.0769230769230769 3.24382178907066 0.268087333676184 0.636997871530411 GO:0031432 titin binding 1/442 13/18639 0.0769230769230769 3.24382178907066 0.268087333676184 0.636997871530411 GO:0035325 Toll-like receptor binding 1/442 13/18639 0.0769230769230769 3.24382178907066 0.268087333676184 0.636997871530411 GO:0043560 insulin receptor substrate binding 1/442 13/18639 0.0769230769230769 3.24382178907066 0.268087333676184 0.636997871530411 GO:0045159 myosin II binding 1/442 13/18639 0.0769230769230769 3.24382178907066 0.268087333676184 0.636997871530411 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/442 13/18639 0.0769230769230769 3.24382178907066 0.268087333676184 0.636997871530411 GO:0051536 iron-sulfur cluster binding 3/442 76/18639 0.0394736842105263 1.664592760181 0.269202763636677 0.636997871530411 GO:0098631 cell adhesion mediator activity 3/442 76/18639 0.0394736842105263 1.664592760181 0.269202763636677 0.636997871530411 GO:0008237 metallopeptidase activity 6/442 184/18639 0.0326086956521739 1.37509836710604 0.272059341274903 0.636997871530411 GO:0051540 metal cluster binding 3/442 77/18639 0.038961038961039 1.64297467238644 0.275649246085736 0.636997871530411 GO:0001046 core promoter sequence-specific DNA binding 2/442 44/18639 0.0454545454545455 1.91680378445084 0.280387679878806 0.636997871530411 GO:0019205 nucleobase-containing compound kinase activity 2/442 44/18639 0.0454545454545455 1.91680378445084 0.280387679878806 0.636997871530411 GO:0030547 signaling receptor inhibitor activity 2/442 44/18639 0.0454545454545455 1.91680378445084 0.280387679878806 0.636997871530411 GO:0043014 alpha-tubulin binding 2/442 44/18639 0.0454545454545455 1.91680378445084 0.280387679878806 0.636997871530411 GO:0005161 platelet-derived growth factor receptor binding 1/442 14/18639 0.0714285714285714 3.01212023270847 0.285455818510026 0.636997871530411 GO:0005545 1-phosphatidylinositol binding 1/442 14/18639 0.0714285714285714 3.01212023270847 0.285455818510026 0.636997871530411 GO:0008392 arachidonate epoxygenase activity 1/442 14/18639 0.0714285714285714 3.01212023270847 0.285455818510026 0.636997871530411 GO:0008474 palmitoyl-(protein) hydrolase activity 1/442 14/18639 0.0714285714285714 3.01212023270847 0.285455818510026 0.636997871530411 GO:0008494 translation activator activity 1/442 14/18639 0.0714285714285714 3.01212023270847 0.285455818510026 0.636997871530411 GO:0016530 metallochaperone activity 1/442 14/18639 0.0714285714285714 3.01212023270847 0.285455818510026 0.636997871530411 GO:0034236 protein kinase A catalytic subunit binding 1/442 14/18639 0.0714285714285714 3.01212023270847 0.285455818510026 0.636997871530411 GO:0044548 S100 protein binding 1/442 14/18639 0.0714285714285714 3.01212023270847 0.285455818510026 0.636997871530411 GO:0070742 C2H2 zinc finger domain binding 1/442 14/18639 0.0714285714285714 3.01212023270847 0.285455818510026 0.636997871530411 GO:0071933 Arp2/3 complex binding 1/442 14/18639 0.0714285714285714 3.01212023270847 0.285455818510026 0.636997871530411 GO:0098599 palmitoyl hydrolase activity 1/442 14/18639 0.0714285714285714 3.01212023270847 0.285455818510026 0.636997871530411 GO:0098847 sequence-specific single stranded DNA binding 1/442 14/18639 0.0714285714285714 3.01212023270847 0.285455818510026 0.636997871530411 GO:1901612 cardiolipin binding 1/442 14/18639 0.0714285714285714 3.01212023270847 0.285455818510026 0.636997871530411 GO:1990825 sequence-specific mRNA binding 1/442 14/18639 0.0714285714285714 3.01212023270847 0.285455818510026 0.636997871530411 GO:0001221 transcription coregulator binding 4/442 115/18639 0.0347826086956522 1.46677159157978 0.290939942631221 0.645087284939512 GO:0017124 SH3 domain binding 4/442 115/18639 0.0347826086956522 1.46677159157978 0.290939942631221 0.645087284939512 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/442 46/18639 0.0434782608695652 1.83346448947472 0.298028337956753 0.656608465212656 GO:0030276 clathrin binding 2/442 46/18639 0.0434782608695652 1.83346448947472 0.298028337956753 0.656608465212656 GO:0031005 filamin binding 1/442 15/18639 0.0666666666666667 2.81131221719457 0.302413054924446 0.664160316827739 GO:0005504 fatty acid binding 2/442 47/18639 0.0425531914893617 1.79445460671994 0.306824811394941 0.671723719583877 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/442 48/18639 0.0416666666666667 1.75707013574661 0.315599808746478 0.683223205663469 GO:0005521 lamin binding 1/442 16/18639 0.0625 2.63560520361991 0.318968758840006 0.683223205663469 GO:0008391 arachidonate monooxygenase activity 1/442 16/18639 0.0625 2.63560520361991 0.318968758840006 0.683223205663469 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/442 16/18639 0.0625 2.63560520361991 0.318968758840006 0.683223205663469 GO:0034450 ubiquitin-ubiquitin ligase activity 1/442 16/18639 0.0625 2.63560520361991 0.318968758840006 0.683223205663469 GO:0055102 lipase inhibitor activity 1/442 16/18639 0.0625 2.63560520361991 0.318968758840006 0.683223205663469 GO:0070411 I-SMAD binding 1/442 16/18639 0.0625 2.63560520361991 0.318968758840006 0.683223205663469 GO:0001222 transcription corepressor binding 2/442 49/18639 0.0408163265306122 1.7212115615477 0.32434940834973 0.688112122774676 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/442 122/18639 0.0327868852459016 1.3826125658334 0.328429859475329 0.688112122774676 GO:0099106 ion channel regulator activity 5/442 160/18639 0.03125 1.31780260180995 0.330339691633859 0.688112122774676 GO:0015605 organophosphate ester transmembrane transporter activity 2/442 50/18639 0.04 1.68678733031674 0.333069885764955 0.688112122774676 GO:0004866 endopeptidase inhibitor activity 5/442 161/18639 0.031055900621118 1.30961749248194 0.33502402051524 0.688112122774676 GO:0004550 nucleoside diphosphate kinase activity 1/442 17/18639 0.0588235294117647 2.48056960340697 0.335132417143862 0.688112122774676 GO:0004659 prenyltransferase activity 1/442 17/18639 0.0588235294117647 2.48056960340697 0.335132417143862 0.688112122774676 GO:0005092 GDP-dissociation inhibitor activity 1/442 17/18639 0.0588235294117647 2.48056960340697 0.335132417143862 0.688112122774676 GO:0008429 phosphatidylethanolamine binding 1/442 17/18639 0.0588235294117647 2.48056960340697 0.335132417143862 0.688112122774676 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/442 17/18639 0.0588235294117647 2.48056960340697 0.335132417143862 0.688112122774676 GO:0030548 acetylcholine receptor regulator activity 1/442 17/18639 0.0588235294117647 2.48056960340697 0.335132417143862 0.688112122774676 GO:0031489 myosin V binding 1/442 17/18639 0.0588235294117647 2.48056960340697 0.335132417143862 0.688112122774676 GO:0036041 long-chain fatty acid binding 1/442 17/18639 0.0588235294117647 2.48056960340697 0.335132417143862 0.688112122774676 GO:0048038 quinone binding 1/442 17/18639 0.0588235294117647 2.48056960340697 0.335132417143862 0.688112122774676 GO:0016830 carbon-carbon lyase activity 2/442 51/18639 0.0392156862745098 1.65371306893798 0.341757706662375 0.699645570571352 GO:0000400 four-way junction DNA binding 1/442 18/18639 0.0555555555555556 2.34276018099548 0.35091329307676 0.701826586153519 GO:0008525 phosphatidylcholine transporter activity 1/442 18/18639 0.0555555555555556 2.34276018099548 0.35091329307676 0.701826586153519 GO:0017128 phospholipid scramblase activity 1/442 18/18639 0.0555555555555556 2.34276018099548 0.35091329307676 0.701826586153519 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/442 18/18639 0.0555555555555556 2.34276018099548 0.35091329307676 0.701826586153519 GO:0050811 GABA receptor binding 1/442 18/18639 0.0555555555555556 2.34276018099548 0.35091329307676 0.701826586153519 GO:0070064 proline-rich region binding 1/442 18/18639 0.0555555555555556 2.34276018099548 0.35091329307676 0.701826586153519 GO:0099602 neurotransmitter receptor regulator activity 1/442 18/18639 0.0555555555555556 2.34276018099548 0.35091329307676 0.701826586153519 GO:1901611 phosphatidylglycerol binding 1/442 18/18639 0.0555555555555556 2.34276018099548 0.35091329307676 0.701826586153519 GO:0003714 transcription corepressor activity 6/442 204/18639 0.0294117647058824 1.24028480170349 0.35503331938791 0.704681668119895 GO:0019783 ubiquitin-like protein peptidase activity 4/442 127/18639 0.031496062992126 1.3281790002494 0.355387008417814 0.704681668119895 GO:0042826 histone deacetylase binding 4/442 127/18639 0.031496062992126 1.3281790002494 0.355387008417814 0.704681668119895 GO:0051018 protein kinase A binding 2/442 53/18639 0.0377358490566038 1.59130880218561 0.359022151032449 0.705839583049632 GO:0140296 general transcription initiation factor binding 2/442 53/18639 0.0377358490566038 1.59130880218561 0.359022151032449 0.705839583049632 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/442 53/18639 0.0377358490566038 1.59130880218561 0.359022151032449 0.705839583049632 GO:0031490 chromatin DNA binding 4/442 128/18639 0.03125 1.31780260180995 0.360782024369999 0.707295833086948 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/442 19/18639 0.0526315789473684 2.21945701357466 0.366320431493605 0.708636836881661 GO:0031420 alkali metal ion binding 1/442 19/18639 0.0526315789473684 2.21945701357466 0.366320431493605 0.708636836881661 GO:0046624 sphingolipid transporter activity 1/442 19/18639 0.0526315789473684 2.21945701357466 0.366320431493605 0.708636836881661 GO:0050145 nucleoside monophosphate kinase activity 1/442 19/18639 0.0526315789473684 2.21945701357466 0.366320431493605 0.708636836881661 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/442 54/18639 0.037037037037037 1.56184012066365 0.367592595500574 0.708636836881661 GO:0051287 NAD binding 2/442 54/18639 0.037037037037037 1.56184012066365 0.367592595500574 0.708636836881661 GO:0042393 histone binding 7/442 247/18639 0.0283400809716599 1.19509223807866 0.370320389402828 0.711917867716241 GO:0098632 cell-cell adhesion mediator activity 2/442 55/18639 0.0363636363636364 1.53344302756067 0.376118012735209 0.715212256625852 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/442 20/18639 0.05 2.10848416289593 0.381362664000577 0.715212256625852 GO:0010851 cyclase regulator activity 1/442 20/18639 0.05 2.10848416289593 0.381362664000577 0.715212256625852 GO:0016408 C-acyltransferase activity 1/442 20/18639 0.05 2.10848416289593 0.381362664000577 0.715212256625852 GO:0016505 peptidase activator activity involved in apoptotic process 1/442 20/18639 0.05 2.10848416289593 0.381362664000577 0.715212256625852 GO:0030627 pre-mRNA 5'-splice site binding 1/442 20/18639 0.05 2.10848416289593 0.381362664000577 0.715212256625852 GO:0052745 inositol phosphate phosphatase activity 1/442 20/18639 0.05 2.10848416289593 0.381362664000577 0.715212256625852 GO:0061608 nuclear import signal receptor activity 1/442 20/18639 0.05 2.10848416289593 0.381362664000577 0.715212256625852 GO:0005179 hormone activity 4/442 132/18639 0.0303030303030303 1.2778691896339 0.382339693383561 0.715212256625852 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/442 132/18639 0.0303030303030303 1.2778691896339 0.382339693383561 0.715212256625852 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/442 57/18639 0.0350877192982456 1.47963800904977 0.393023186216642 0.727136873270735 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/442 21/18639 0.0476190476190476 2.00808015513898 0.396048613971668 0.727136873270735 GO:0035613 RNA stem-loop binding 1/442 21/18639 0.0476190476190476 2.00808015513898 0.396048613971668 0.727136873270735 GO:0036122 BMP binding 1/442 21/18639 0.0476190476190476 2.00808015513898 0.396048613971668 0.727136873270735 GO:0061891 calcium ion sensor activity 1/442 21/18639 0.0476190476190476 2.00808015513898 0.396048613971668 0.727136873270735 GO:0070182 DNA polymerase binding 1/442 21/18639 0.0476190476190476 2.00808015513898 0.396048613971668 0.727136873270735 GO:0072542 protein phosphatase activator activity 1/442 21/18639 0.0476190476190476 2.00808015513898 0.396048613971668 0.727136873270735 GO:0016741 transferase activity, transferring one-carbon groups 6/442 215/18639 0.027906976744186 1.17682836998842 0.401583866981543 0.734042192795221 GO:0019838 growth factor binding 4/442 136/18639 0.0294117647058824 1.24028480170349 0.403814896927566 0.734042192795221 GO:0015459 potassium channel regulator activity 2/442 59/18639 0.0338983050847458 1.42948078840402 0.409717998476916 0.734042192795221 GO:0036002 pre-mRNA binding 2/442 59/18639 0.0338983050847458 1.42948078840402 0.409717998476916 0.734042192795221 GO:0045309 protein phosphorylated amino acid binding 2/442 59/18639 0.0338983050847458 1.42948078840402 0.409717998476916 0.734042192795221 GO:0008649 rRNA methyltransferase activity 1/442 22/18639 0.0454545454545455 1.91680378445084 0.410386701447472 0.734042192795221 GO:0033691 sialic acid binding 1/442 22/18639 0.0454545454545455 1.91680378445084 0.410386701447472 0.734042192795221 GO:0034062 5'-3' RNA polymerase activity 1/442 22/18639 0.0454545454545455 1.91680378445084 0.410386701447472 0.734042192795221 GO:0097747 RNA polymerase activity 1/442 22/18639 0.0454545454545455 1.91680378445084 0.410386701447472 0.734042192795221 GO:0140784 metal ion sensor activity 1/442 22/18639 0.0454545454545455 1.91680378445084 0.410386701447472 0.734042192795221 GO:0042626 ATPase-coupled transmembrane transporter activity 3/442 98/18639 0.0306122448979592 1.29090867116077 0.411534649684245 0.73420320534927 GO:0001098 basal transcription machinery binding 2/442 60/18639 0.0333333333333333 1.40565610859728 0.417980992306365 0.741889536216412 GO:0001099 basal RNA polymerase II transcription machinery binding 2/442 60/18639 0.0333333333333333 1.40565610859728 0.417980992306365 0.741889536216412 GO:0017134 fibroblast growth factor binding 1/442 23/18639 0.0434782608695652 1.83346448947472 0.424385147918989 0.743745688524692 GO:0043274 phospholipase binding 1/442 23/18639 0.0434782608695652 1.83346448947472 0.424385147918989 0.743745688524692 GO:0070577 lysine-acetylated histone binding 1/442 23/18639 0.0434782608695652 1.83346448947472 0.424385147918989 0.743745688524692 GO:0099186 structural constituent of postsynapse 1/442 23/18639 0.0434782608695652 1.83346448947472 0.424385147918989 0.743745688524692 GO:0140102 catalytic activity, acting on a rRNA 1/442 23/18639 0.0434782608695652 1.83346448947472 0.424385147918989 0.743745688524692 GO:0005315 phosphate transmembrane transporter activity 1/442 24/18639 0.0416666666666667 1.75707013574661 0.438051980999124 0.756238992073115 GO:0005540 hyaluronic acid binding 1/442 24/18639 0.0416666666666667 1.75707013574661 0.438051980999124 0.756238992073115 GO:0035035 histone acetyltransferase binding 1/442 24/18639 0.0416666666666667 1.75707013574661 0.438051980999124 0.756238992073115 GO:0050431 transforming growth factor beta binding 1/442 24/18639 0.0416666666666667 1.75707013574661 0.438051980999124 0.756238992073115 GO:0050699 WW domain binding 1/442 24/18639 0.0416666666666667 1.75707013574661 0.438051980999124 0.756238992073115 GO:0140033 acetylation-dependent protein binding 1/442 24/18639 0.0416666666666667 1.75707013574661 0.438051980999124 0.756238992073115 GO:0004536 DNA nuclease activity 2/442 64/18639 0.03125 1.31780260180995 0.450425483045709 0.771596445948931 GO:0017056 structural constituent of nuclear pore 1/442 25/18639 0.04 1.68678733031674 0.451395038984533 0.771596445948931 GO:0019211 phosphatase activator activity 1/442 25/18639 0.04 1.68678733031674 0.451395038984533 0.771596445948931 GO:0120020 cholesterol transfer activity 1/442 25/18639 0.04 1.68678733031674 0.451395038984533 0.771596445948931 GO:0120013 lipid transfer activity 2/442 65/18639 0.0307692307692308 1.29752871562826 0.458376354828147 0.781604890050943 GO:0004435 phosphatidylinositol phospholipase C activity 1/442 26/18639 0.0384615384615385 1.62191089453533 0.464421975310354 0.782616654167288 GO:0008143 poly(A) binding 1/442 26/18639 0.0384615384615385 1.62191089453533 0.464421975310354 0.782616654167288 GO:0034237 protein kinase A regulatory subunit binding 1/442 26/18639 0.0384615384615385 1.62191089453533 0.464421975310354 0.782616654167288 GO:0120014 phospholipid transfer activity 1/442 26/18639 0.0384615384615385 1.62191089453533 0.464421975310354 0.782616654167288 GO:0005085 guanyl-nucleotide exchange factor activity 6/442 230/18639 0.0260869565217391 1.10007869368483 0.464608157805364 0.782616654167288 GO:0019209 kinase activator activity 4/442 148/18639 0.027027027027027 1.13972116913293 0.467182472915605 0.785047545286755 GO:0008509 monoatomic anion transmembrane transporter activity 4/442 149/18639 0.0268456375838926 1.13207203376963 0.472362458968687 0.791834653440263 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/442 67/18639 0.0298507462686567 1.25879651516175 0.474075626534134 0.792189814480506 GO:0004364 glutathione transferase activity 1/442 27/18639 0.037037037037037 1.56184012066365 0.477140262900363 0.792189814480506 GO:0015252 proton channel activity 1/442 27/18639 0.037037037037037 1.56184012066365 0.477140262900363 0.792189814480506 GO:0023026 MHC class II protein complex binding 1/442 27/18639 0.037037037037037 1.56184012066365 0.477140262900363 0.792189814480506 GO:0005548 phospholipid transporter activity 2/442 68/18639 0.0294117647058824 1.24028480170349 0.481821535472839 0.798052853503938 GO:0008236 serine-type peptidase activity 5/442 194/18639 0.0257731958762887 1.08684750664739 0.48877581718149 0.805101174644539 GO:0019789 SUMO transferase activity 1/442 28/18639 0.0357142857142857 1.50606011635423 0.489557198414979 0.805101174644539 GO:0046875 ephrin receptor binding 1/442 28/18639 0.0357142857142857 1.50606011635423 0.489557198414979 0.805101174644539 GO:0003774 cytoskeletal motor activity 4/442 153/18639 0.0261437908496732 1.10247537929199 0.492888166631702 0.80764555880117 GO:0004175 endopeptidase activity 10/442 405/18639 0.0246913580246914 1.0412267471091 0.49343186877766 0.80764555880117 GO:0003785 actin monomer binding 1/442 29/18639 0.0344827586206897 1.45412700889374 0.501679906399536 0.813471623928219 GO:0004629 phospholipase C activity 1/442 29/18639 0.0344827586206897 1.45412700889374 0.501679906399536 0.813471623928219 GO:0043236 laminin binding 1/442 29/18639 0.0344827586206897 1.45412700889374 0.501679906399536 0.813471623928219 GO:0051861 glycolipid binding 1/442 29/18639 0.0344827586206897 1.45412700889374 0.501679906399536 0.813471623928219 GO:0140299 molecular sensor activity 2/442 71/18639 0.028169014084507 1.18787840163151 0.504631401081094 0.815164013763565 GO:0017171 serine hydrolase activity 5/442 198/18639 0.0252525252525253 1.06489099136158 0.506741210293325 0.815164013763565 GO:0031267 small GTPase binding 7/442 283/18639 0.0247349823321555 1.04306637033721 0.508541056504285 0.815164013763565 GO:0001968 fibronectin binding 1/442 30/18639 0.0333333333333333 1.40565610859728 0.51351534333513 0.815164013763565 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/442 30/18639 0.0333333333333333 1.40565610859728 0.51351534333513 0.815164013763565 GO:0016769 transferase activity, transferring nitrogenous groups 1/442 30/18639 0.0333333333333333 1.40565610859728 0.51351534333513 0.815164013763565 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/442 30/18639 0.0333333333333333 1.40565610859728 0.51351534333513 0.815164013763565 GO:0098918 structural constituent of synapse 1/442 30/18639 0.0333333333333333 1.40565610859728 0.51351534333513 0.815164013763565 GO:0035401 histone H3Y41 kinase activity 3/442 115/18639 0.0260869565217391 1.10007869368483 0.515644095161679 0.815164013763565 GO:0101005 deubiquitinase activity 3/442 115/18639 0.0260869565217391 1.10007869368483 0.515644095161679 0.815164013763565 GO:0140801 histone H2AXY142 kinase activity 3/442 115/18639 0.0260869565217391 1.10007869368483 0.515644095161679 0.815164013763565 GO:0043539 protein serine/threonine kinase activator activity 2/442 73/18639 0.0273972602739726 1.15533378788818 0.519472395194036 0.819349641510593 GO:0005184 neuropeptide hormone activity 1/442 31/18639 0.032258064516129 1.36031236315866 0.525070301594352 0.823391825001192 GO:0047499 calcium-independent phospholipase A2 activity 1/442 31/18639 0.032258064516129 1.36031236315866 0.525070301594352 0.823391825001192 GO:0003678 DNA helicase activity 2/442 74/18639 0.027027027027027 1.13972116913293 0.526780937032463 0.823391825001192 GO:0031491 nucleosome binding 2/442 74/18639 0.027027027027027 1.13972116913293 0.526780937032463 0.823391825001192 GO:0008168 methyltransferase activity 5/442 204/18639 0.0245098039215686 1.03357066808624 0.533203470768181 0.827173068517904 GO:0033218 amide binding 6/442 247/18639 0.0242914979757085 1.024364775496 0.533750372606443 0.827173068517904 GO:0047498 calcium-dependent phospholipase A2 activity 1/442 32/18639 0.03125 1.31780260180995 0.536351413304116 0.827173068517904 GO:0070717 poly-purine tract binding 1/442 32/18639 0.03125 1.31780260180995 0.536351413304116 0.827173068517904 GO:0120015 sterol transfer activity 1/442 32/18639 0.03125 1.31780260180995 0.536351413304116 0.827173068517904 GO:0160041 neuropeptide activity 1/442 32/18639 0.03125 1.31780260180995 0.536351413304116 0.827173068517904 GO:0140104 molecular carrier activity 6/442 249/18639 0.0240963855421687 1.01613694597394 0.541647910243928 0.833489245475136 GO:0005516 calmodulin binding 5/442 207/18639 0.0241545893719807 1.01859138304151 0.546193322721114 0.836721182726277 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/442 33/18639 0.0303030303030303 1.2778691896339 0.547365154117766 0.836721182726277 GO:0140311 protein sequestering activity 1/442 33/18639 0.0303030303030303 1.2778691896339 0.547365154117766 0.836721182726277 GO:0016831 carboxy-lyase activity 1/442 34/18639 0.0294117647058824 1.24028480170349 0.558117846898587 0.847557518047307 GO:0019825 oxygen binding 1/442 34/18639 0.0294117647058824 1.24028480170349 0.558117846898587 0.847557518047307 GO:0030332 cyclin binding 1/442 34/18639 0.0294117647058824 1.24028480170349 0.558117846898587 0.847557518047307 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 4/442 167/18639 0.0239520958083832 1.01005229360284 0.561831369810043 0.850009113932523 GO:0033293 monocarboxylic acid binding 2/442 79/18639 0.0253164556962025 1.06758691792199 0.562181820309839 0.850009113932523 GO:0004623 phospholipase A2 activity 1/442 35/18639 0.0285714285714286 1.20484809308339 0.568615665316798 0.850226798036412 GO:0034061 DNA polymerase activity 1/442 35/18639 0.0285714285714286 1.20484809308339 0.568615665316798 0.850226798036412 GO:0140566 histone reader activity 1/442 35/18639 0.0285714285714286 1.20484809308339 0.568615665316798 0.850226798036412 GO:0033192 calmodulin-dependent protein phosphatase activity 2/442 81/18639 0.0246913580246914 1.0412267471091 0.57580201019757 0.850226798036412 GO:0140791 histone H2AXS140 phosphatase activity 2/442 81/18639 0.0246913580246914 1.0412267471091 0.57580201019757 0.850226798036412 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/442 81/18639 0.0246913580246914 1.0412267471091 0.57580201019757 0.850226798036412 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/442 81/18639 0.0246913580246914 1.0412267471091 0.57580201019757 0.850226798036412 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/442 81/18639 0.0246913580246914 1.0412267471091 0.57580201019757 0.850226798036412 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/442 81/18639 0.0246913580246914 1.0412267471091 0.57580201019757 0.850226798036412 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/442 81/18639 0.0246913580246914 1.0412267471091 0.57580201019757 0.850226798036412 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/442 81/18639 0.0246913580246914 1.0412267471091 0.57580201019757 0.850226798036412 GO:0004033 aldo-keto reductase (NADPH) activity 1/442 36/18639 0.0277777777777778 1.17138009049774 0.578864637362056 0.851127242223023 GO:0016409 palmitoyltransferase activity 1/442 36/18639 0.0277777777777778 1.17138009049774 0.578864637362056 0.851127242223023 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/442 82/18639 0.024390243902439 1.02852885994923 0.582495328591607 0.852851810216403 GO:0033549 MAP kinase phosphatase activity 2/442 82/18639 0.024390243902439 1.02852885994923 0.582495328591607 0.852851810216403 GO:0023023 MHC protein complex binding 1/442 37/18639 0.027027027027027 1.13972116913293 0.58887064877344 0.857112722730989 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/442 83/18639 0.0240963855421687 1.01613694597394 0.589110617784844 0.857112722730989 GO:0005254 chloride channel activity 2/442 83/18639 0.0240963855421687 1.01613694597394 0.589110617784844 0.857112722730989 GO:0003730 mRNA 3'-UTR binding 6/442 262/18639 0.0229007633587786 0.965717937204242 0.59146788971359 0.858742082554878 GO:0017018 myosin phosphatase activity 2/442 84/18639 0.0238095238095238 1.00404007756949 0.59564780650498 0.863005381449804 GO:0043531 ADP binding 1/442 38/18639 0.0263157894736842 1.10972850678733 0.598639446388865 0.864047837188498 GO:0004721 phosphoprotein phosphatase activity 4/442 175/18639 0.0228571428571429 0.96387847446671 0.598857362662345 0.864047837188498 GO:0004252 serine-type endopeptidase activity 4/442 176/18639 0.0227272727272727 0.958401892225422 0.603352231535583 0.868727071962022 GO:0050660 flavin adenine dinucleotide binding 2/442 86/18639 0.0232558139534884 0.980690308323687 0.608487830989576 0.874307566680675 GO:0140297 DNA-binding transcription factor binding 11/442 488/18639 0.0225409836065574 0.950546139010459 0.610840426642134 0.875874496052977 GO:0030331 nuclear estrogen receptor binding 1/442 40/18639 0.025 1.05424208144796 0.617487712625172 0.879951689038746 GO:0071855 neuropeptide receptor binding 1/442 40/18639 0.025 1.05424208144796 0.617487712625172 0.879951689038746 GO:0071949 FAD binding 1/442 40/18639 0.025 1.05424208144796 0.617487712625172 0.879951689038746 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/442 181/18639 0.0220994475138122 0.931926701832454 0.625364072176355 0.889253862111005 GO:0001530 lipopolysaccharide binding 1/442 41/18639 0.024390243902439 1.02852885994923 0.626578009470146 0.889253862111005 GO:0016779 nucleotidyltransferase activity 3/442 136/18639 0.0220588235294118 0.930213601277615 0.629262899745484 0.889426583346977 GO:0140789 histone phosphatase activity 3/442 136/18639 0.0220588235294118 0.930213601277615 0.629262899745484 0.889426583346977 GO:0016922 nuclear receptor binding 3/442 137/18639 0.0218978102189781 0.923423720976319 0.634190490418036 0.890917600124086 GO:0004402 histone acetyltransferase activity 1/442 42/18639 0.0238095238095238 1.00404007756949 0.635452755131733 0.890917600124086 GO:0004520 DNA endonuclease activity 1/442 42/18639 0.0238095238095238 1.00404007756949 0.635452755131733 0.890917600124086 GO:0048487 beta-tubulin binding 1/442 42/18639 0.0238095238095238 1.00404007756949 0.635452755131733 0.890917600124086 GO:0030295 protein kinase activator activity 3/442 139/18639 0.0215827338129496 0.910137048732055 0.643908623527821 0.900952791790943 GO:0004713 protein tyrosine kinase activity 3/442 140/18639 0.0214285714285714 0.90363606981254 0.648698978964783 0.903967375642883 GO:0031406 carboxylic acid binding 4/442 187/18639 0.0213903743315508 0.902025310329809 0.650735286273489 0.903967375642883 GO:0051213 dioxygenase activity 2/442 93/18639 0.021505376344086 0.906874908772442 0.65097789952826 0.903967375642883 GO:0001223 transcription coactivator binding 1/442 44/18639 0.0227272727272727 0.958401892225422 0.652575872041908 0.903967375642883 GO:0016790 thiolester hydrolase activity 1/442 44/18639 0.0227272727272727 0.958401892225422 0.652575872041908 0.903967375642883 GO:0042562 hormone binding 2/442 94/18639 0.0212765957446809 0.897227303359969 0.656739512528255 0.906361373099857 GO:0043177 organic acid binding 4/442 189/18639 0.0211640211640212 0.892480068950657 0.658934227198914 0.906361373099857 GO:0016887 ATP hydrolysis activity 9/442 417/18639 0.0215827338129496 0.910137048732055 0.659569359743908 0.906361373099857 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/442 45/18639 0.0222222222222222 0.93710407239819 0.660834084709694 0.906361373099857 GO:0140303 intramembrane lipid transporter activity 1/442 45/18639 0.0222222222222222 0.93710407239819 0.660834084709694 0.906361373099857 GO:0004180 carboxypeptidase activity 1/442 46/18639 0.0217391304347826 0.91673224473736 0.668896434637537 0.915609715263217 GO:0001784 phosphotyrosine residue binding 1/442 47/18639 0.0212765957446809 0.897227303359969 0.676767556881941 0.920508054881001 GO:0061733 protein-lysine-acetyltransferase activity 1/442 47/18639 0.0212765957446809 0.897227303359969 0.676767556881941 0.920508054881001 GO:0005539 glycosaminoglycan binding 5/442 242/18639 0.0206611570247934 0.871274447477656 0.683133294776955 0.920508054881001 GO:0140097 catalytic activity, acting on DNA 7/442 336/18639 0.0208333333333333 0.878535067873303 0.687787304628795 0.920508054881001 GO:0005004 GPI-linked ephrin receptor activity 1/442 49/18639 0.0204081632653061 0.860605780773848 0.691954113903064 0.920508054881001 GO:0005008 hepatocyte growth factor receptor activity 1/442 49/18639 0.0204081632653061 0.860605780773848 0.691954113903064 0.920508054881001 GO:0005009 insulin receptor activity 1/442 49/18639 0.0204081632653061 0.860605780773848 0.691954113903064 0.920508054881001 GO:0005011 macrophage colony-stimulating factor receptor activity 1/442 49/18639 0.0204081632653061 0.860605780773848 0.691954113903064 0.920508054881001 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/442 49/18639 0.0204081632653061 0.860605780773848 0.691954113903064 0.920508054881001 GO:0005020 stem cell factor receptor activity 1/442 49/18639 0.0204081632653061 0.860605780773848 0.691954113903064 0.920508054881001 GO:0008288 boss receptor activity 1/442 49/18639 0.0204081632653061 0.860605780773848 0.691954113903064 0.920508054881001 GO:0036332 placental growth factor receptor activity 1/442 49/18639 0.0204081632653061 0.860605780773848 0.691954113903064 0.920508054881001 GO:0038062 protein tyrosine kinase collagen receptor activity 1/442 49/18639 0.0204081632653061 0.860605780773848 0.691954113903064 0.920508054881001 GO:0060175 brain-derived neurotrophic factor receptor activity 1/442 49/18639 0.0204081632653061 0.860605780773848 0.691954113903064 0.920508054881001 GO:0005006 epidermal growth factor receptor activity 1/442 50/18639 0.02 0.843393665158371 0.69927828182425 0.920508054881001 GO:0005007 fibroblast growth factor receptor activity 1/442 50/18639 0.02 0.843393665158371 0.69927828182425 0.920508054881001 GO:0005017 platelet-derived growth factor receptor activity 1/442 50/18639 0.02 0.843393665158371 0.69927828182425 0.920508054881001 GO:0005019 platelet-derived growth factor beta-receptor activity 1/442 50/18639 0.02 0.843393665158371 0.69927828182425 0.920508054881001 GO:0048020 CCR chemokine receptor binding 1/442 50/18639 0.02 0.843393665158371 0.69927828182425 0.920508054881001 GO:0019787 ubiquitin-like protein transferase activity 10/442 479/18639 0.0208768267223382 0.880369170311452 0.703109538028332 0.920508054881001 GO:0004722 protein serine/threonine phosphatase activity 2/442 103/18639 0.0194174757281553 0.818828801124632 0.705213165461924 0.920508054881001 GO:0005010 insulin-like growth factor receptor activity 1/442 51/18639 0.0196078431372549 0.826856534468991 0.706428693327487 0.920508054881001 GO:0005021 vascular endothelial growth factor receptor activity 1/442 51/18639 0.0196078431372549 0.826856534468991 0.706428693327487 0.920508054881001 GO:0005030 neurotrophin receptor activity 1/442 51/18639 0.0196078431372549 0.826856534468991 0.706428693327487 0.920508054881001 GO:0042277 peptide binding 5/442 249/18639 0.0200803212851406 0.846780788311618 0.706906117011795 0.920508054881001 GO:0005080 protein kinase C binding 1/442 52/18639 0.0192307692307692 0.810955447267665 0.713409461433214 0.920508054881001 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/442 52/18639 0.0192307692307692 0.810955447267665 0.713409461433214 0.920508054881001 GO:0004386 helicase activity 3/442 155/18639 0.0193548387096774 0.816187417895198 0.715046905961542 0.920508054881001 GO:0004864 protein phosphatase inhibitor activity 1/442 53/18639 0.0188679245283019 0.795654401092803 0.720224602017844 0.920508054881001 GO:0005003 ephrin receptor activity 1/442 53/18639 0.0188679245283019 0.795654401092803 0.720224602017844 0.920508054881001 GO:0005005 transmembrane-ephrin receptor activity 1/442 53/18639 0.0188679245283019 0.795654401092803 0.720224602017844 0.920508054881001 GO:0005544 calcium-dependent phospholipid binding 1/442 53/18639 0.0188679245283019 0.795654401092803 0.720224602017844 0.920508054881001 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/442 53/18639 0.0188679245283019 0.795654401092803 0.720224602017844 0.920508054881001 GO:0017046 peptide hormone binding 1/442 53/18639 0.0188679245283019 0.795654401092803 0.720224602017844 0.920508054881001 GO:0034212 protein N-acetyltransferase activity 1/442 53/18639 0.0188679245283019 0.795654401092803 0.720224602017844 0.920508054881001 GO:0038064 collagen receptor activity 1/442 53/18639 0.0188679245283019 0.795654401092803 0.720224602017844 0.920508054881001 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 7/442 349/18639 0.0200573065902579 0.845810265918137 0.724713207858196 0.922218203026571 GO:0019888 protein phosphatase regulator activity 2/442 107/18639 0.0186915887850467 0.788218378652683 0.724860742652445 0.922218203026571 GO:0050661 NADP binding 1/442 54/18639 0.0185185185185185 0.780920060331825 0.726878036103075 0.922218203026571 GO:0140463 chromatin-protein adaptor activity 1/442 54/18639 0.0185185185185185 0.780920060331825 0.726878036103075 0.922218203026571 GO:0004843 cysteine-type deubiquitinase activity 2/442 108/18639 0.0185185185185185 0.780920060331825 0.729596579994366 0.923978150576806 GO:0008374 O-acyltransferase activity 1/442 55/18639 0.0181818181818182 0.766721513780337 0.733373592091369 0.926506629350065 GO:0004620 phospholipase activity 2/442 109/18639 0.018348623853211 0.773755656108597 0.734263178879735 0.926506629350065 GO:0005178 integrin binding 3/442 161/18639 0.0186335403726708 0.785770495489166 0.738727459174493 0.927052070457555 GO:0019212 phosphatase inhibitor activity 1/442 56/18639 0.0178571428571429 0.753030058177117 0.73971500794886 0.927052070457555 GO:0030170 pyridoxal phosphate binding 1/442 56/18639 0.0178571428571429 0.753030058177117 0.73971500794886 0.927052070457555 GO:0004842 ubiquitin-protein transferase activity 9/442 449/18639 0.0200445434298441 0.845272047486118 0.741435054921956 0.927052070457555 GO:0008083 growth factor activity 3/442 162/18639 0.0185185185185185 0.780920060331825 0.742519007903813 0.927052070457555 GO:0016755 aminoacyltransferase activity 10/442 496/18639 0.0201612903225806 0.850195226974164 0.74271030428588 0.927052070457555 GO:0070279 vitamin B6 binding 1/442 57/18639 0.0175438596491228 0.739819004524887 0.745905933336936 0.929369331662179 GO:0008408 3'-5' exonuclease activity 1/442 58/18639 0.0172413793103448 0.727063504446872 0.751949931693683 0.935220882787484 GO:0015103 inorganic anion transmembrane transporter activity 3/442 165/18639 0.0181818181818182 0.766721513780337 0.75363163469624 0.935635696742737 GO:0001786 phosphatidylserine binding 1/442 59/18639 0.0169491525423729 0.714740394202009 0.757850482266386 0.939193276237271 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/442 60/18639 0.0166666666666667 0.702828054298642 0.763610982096217 0.942964451200666 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/442 60/18639 0.0166666666666667 0.702828054298642 0.763610982096217 0.942964451200666 GO:0015294 solute:monoatomic cation symporter activity 2/442 116/18639 0.0172413793103448 0.727063504446872 0.765043256783835 0.943055098060358 GO:0019208 phosphatase regulator activity 2/442 117/18639 0.0170940170940171 0.720849286460146 0.769178717701959 0.943195963041757 GO:0015026 coreceptor activity 1/442 61/18639 0.0163934426229508 0.691306282916698 0.769234747956245 0.943195963041757 GO:0019905 syntaxin binding 1/442 61/18639 0.0163934426229508 0.691306282916698 0.769234747956245 0.943195963041757 GO:0046982 protein heterodimerization activity 7/442 369/18639 0.018970189701897 0.799966891071626 0.775487106688165 0.949185276969289 GO:0016791 phosphatase activity 5/442 273/18639 0.0183150183150183 0.7723385212073 0.778787205964431 0.951546339681892 GO:0005126 cytokine receptor binding 5/442 275/18639 0.0181818181818182 0.766721513780337 0.784113891162932 0.955885117710438 GO:0015108 chloride transmembrane transporter activity 2/442 121/18639 0.0165289256198347 0.697019557982125 0.78509296411376 0.955885117710438 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/442 122/18639 0.0163934426229508 0.691306282916698 0.788918026480855 0.958860088227169 GO:0030246 carbohydrate binding 5/442 280/18639 0.0178571428571429 0.753030058177117 0.796996754183801 0.962557580436621 GO:0005319 lipid transporter activity 3/442 178/18639 0.0168539325842697 0.710724998728964 0.797388979173241 0.962557580436621 GO:0008173 RNA methyltransferase activity 1/442 67/18639 0.0149253731343284 0.629398257580874 0.800282022927854 0.962557580436621 GO:0016500 protein-hormone receptor activity 1/442 67/18639 0.0149253731343284 0.629398257580874 0.800282022927854 0.962557580436621 GO:0042054 histone methyltransferase activity 1/442 67/18639 0.0149253731343284 0.629398257580874 0.800282022927854 0.962557580436621 GO:0050840 extracellular matrix binding 1/442 67/18639 0.0149253731343284 0.629398257580874 0.800282022927854 0.962557580436621 GO:0003777 microtubule motor activity 1/442 68/18639 0.0147058823529412 0.620142400851743 0.80503516453166 0.963266214112021 GO:0140223 general transcription initiation factor activity 1/442 68/18639 0.0147058823529412 0.620142400851743 0.80503516453166 0.963266214112021 GO:1990841 promoter-specific chromatin binding 1/442 68/18639 0.0147058823529412 0.620142400851743 0.80503516453166 0.963266214112021 GO:0002039 p53 binding 1/442 69/18639 0.0144927536231884 0.611154829824907 0.809675434698964 0.96548926405684 GO:0008080 N-acetyltransferase activity 1/442 69/18639 0.0144927536231884 0.611154829824907 0.809675434698964 0.96548926405684 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/442 70/18639 0.0142857142857143 0.602424046541694 0.814205507820292 0.969225767456745 GO:0016298 lipase activity 2/442 130/18639 0.0153846153846154 0.648764357814132 0.817415352735133 0.969720093672107 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/442 130/18639 0.0153846153846154 0.648764357814132 0.817415352735133 0.969720093672107 GO:0005518 collagen binding 1/442 72/18639 0.0138888888888889 0.585690045248869 0.822945445844846 0.970572232805063 GO:0042379 chemokine receptor binding 1/442 72/18639 0.0138888888888889 0.585690045248869 0.822945445844846 0.970572232805063 GO:0030695 GTPase regulator activity 9/442 489/18639 0.0184049079754601 0.776129139716292 0.823437332374197 0.970572232805063 GO:0008234 cysteine-type peptidase activity 3/442 187/18639 0.0160427807486631 0.676518982747357 0.823727730723606 0.970572232805063 GO:0060589 nucleoside-triphosphatase regulator activity 9/442 490/18639 0.0183673469387755 0.774545202696463 0.825201485328285 0.970660730199711 GO:0015297 antiporter activity 2/442 135/18639 0.0148148148148148 0.62473604826546 0.833431986789411 0.978683246754402 GO:0001664 G protein-coupled receptor binding 5/442 297/18639 0.0168350168350168 0.709927327574386 0.836320550594424 0.979762730116557 GO:0005543 phospholipid binding 9/442 497/18639 0.0181086519114688 0.763636115334541 0.837174782361842 0.979762730116557 GO:0035402 histone H3T11 kinase activity 4/442 247/18639 0.0161943319838057 0.682909850330665 0.840676825606779 0.982204910725765 GO:0003724 RNA helicase activity 1/442 77/18639 0.012987012987013 0.547658224128812 0.843042242142509 0.983313136213279 GO:0140767 enzyme-substrate adaptor activity 2/442 139/18639 0.0143884892086331 0.606758032488037 0.845321295309149 0.983662212138778 GO:0019199 transmembrane receptor protein kinase activity 1/442 78/18639 0.0128205128205128 0.54063696484511 0.846779734275523 0.983662212138778 GO:0141003 histone H2AX kinase activity 6/442 354/18639 0.0169491525423729 0.714740394202009 0.84802230789186 0.983662212138778 GO:0008186 ATP-dependent activity, acting on RNA 1/442 79/18639 0.0126582278481013 0.533793458960994 0.850428425480211 0.983662212138778 GO:0046332 SMAD binding 1/442 79/18639 0.0126582278481013 0.533793458960994 0.850428425480211 0.983662212138778 GO:0140996 histone H3 kinase activity 6/442 357/18639 0.0168067226890756 0.708734172401992 0.853502053344054 0.985477917459898 GO:0001618 virus receptor activity 1/442 81/18639 0.0123456790123457 0.52061337355455 0.857467776085413 0.985477917459898 GO:0030971 receptor tyrosine kinase binding 1/442 81/18639 0.0123456790123457 0.52061337355455 0.857467776085413 0.985477917459898 GO:0035173 histone kinase activity 6/442 360/18639 0.0166666666666667 0.702828054298642 0.858819328666482 0.985477917459898 GO:0019955 cytokine binding 2/442 144/18639 0.0138888888888889 0.585690045248869 0.859098184529162 0.985477917459898 GO:0140272 exogenous protein binding 1/442 82/18639 0.0121951219512195 0.514264429974617 0.86086249765941 0.98587223329312 GO:0042578 phosphoric ester hydrolase activity 6/442 363/18639 0.0165289256198347 0.697019557982125 0.863977057032558 0.986539549965225 GO:0015293 symporter activity 2/442 146/18639 0.0136986301369863 0.57766689394409 0.864288251266364 0.986539549965225 GO:0004527 exonuclease activity 1/442 84/18639 0.0119047619047619 0.502020038784745 0.867411830980616 0.988479163711901 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/442 86/18639 0.0116279069767442 0.490345154161844 0.873653545629022 0.993200985245429 GO:0008081 phosphoric diester hydrolase activity 1/442 87/18639 0.0114942528735632 0.484709002964581 0.876663578121447 0.993200985245429 GO:0008094 ATP-dependent activity, acting on DNA 3/442 210/18639 0.0142857142857143 0.602424046541694 0.878091655413131 0.993200985245429 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/442 89/18639 0.0112359550561798 0.47381666581931 0.882470685548676 0.993200985245429 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/442 89/18639 0.0112359550561798 0.47381666581931 0.882470685548676 0.993200985245429 GO:0140793 histone H2AXY142 phosphatase activity 1/442 90/18639 0.0111111111111111 0.468552036199095 0.885271114496788 0.993200985245429 GO:0072341 modified amino acid binding 1/442 91/18639 0.010989010989011 0.46340311272438 0.888004963620321 0.993200985245429 GO:0004674 protein serine/threonine kinase activity 7/442 433/18639 0.0161662817551963 0.681726981074896 0.891541831605479 0.993200985245429 GO:0016410 N-acyltransferase activity 1/442 94/18639 0.0106382978723404 0.448613651679985 0.895822640226841 0.993200985245429 GO:0016407 acetyltransferase activity 1/442 96/18639 0.0104166666666667 0.439267533936652 0.900729501591841 0.993200985245429 GO:0004725 protein tyrosine phosphatase activity 1/442 98/18639 0.0102040816326531 0.430302890386924 0.905405742956642 0.993200985245429 GO:0008170 N-methyltransferase activity 1/442 98/18639 0.0102040816326531 0.430302890386924 0.905405742956642 0.993200985245429 GO:0035091 phosphatidylinositol binding 4/442 284/18639 0.0140845070422535 0.593939200815754 0.907707844948695 0.993200985245429 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/442 229/18639 0.0131004366812227 0.552441265387579 0.911208930757446 0.993200985245429 GO:0015291 secondary active transmembrane transporter activity 4/442 287/18639 0.0139372822299652 0.587730777113847 0.911855146906607 0.993200985245429 GO:0008238 exopeptidase activity 1/442 102/18639 0.00980392156862745 0.413428267234496 0.914109121959222 0.993200985245429 GO:0008201 heparin binding 2/442 172/18639 0.0116279069767442 0.490345154161844 0.917517742560629 0.993200985245429 GO:0005244 voltage-gated monoatomic ion channel activity 2/442 173/18639 0.0115606936416185 0.487510789108885 0.919109931839366 0.993200985245429 GO:0000149 SNARE binding 1/442 106/18639 0.00943396226415094 0.397827200546401 0.922013369176077 0.993200985245429 GO:0022832 voltage-gated channel activity 2/442 175/18639 0.0114285714285714 0.481939237233355 0.922208076715685 0.993200985245429 GO:0061630 ubiquitin protein ligase activity 5/442 353/18639 0.0141643059490085 0.59730429543794 0.924122855078703 0.993200985245429 GO:0045182 translation regulator activity 5/442 356/18639 0.0140449438202247 0.592270832274137 0.927352110844027 0.993200985245429 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/442 243/18639 0.0123456790123457 0.52061337355455 0.930144665126008 0.993200985245429 GO:1902936 phosphatidylinositol bisphosphate binding 1/442 111/18639 0.00900900900900901 0.379907056377645 0.930880804982193 0.993200985245429 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0004711 ribosomal protein S6 kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0035175 histone H3S10 kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0035979 histone H2AXS139 kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0044022 histone H3S28 kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0044023 histone H4S1 kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0044024 histone H2AS1 kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0044025 histone H2BS14 kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0072354 histone H3T3 kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0072371 histone H2AS121 kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0140823 histone H2BS36 kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0140855 histone H3S57 kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0140995 histone H2A kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0140997 histone H4 kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0140998 histone H2B kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:1990244 histone H2AT120 kinase activity 3/442 245/18639 0.0122448979591837 0.516363468464309 0.932525014127552 0.993200985245429 GO:0004677 DNA-dependent protein kinase activity 3/442 246/18639 0.0121951219512195 0.514264429974617 0.933687019259815 0.993200985245429 GO:0140857 histone H3T45 kinase activity 3/442 246/18639 0.0121951219512195 0.514264429974617 0.933687019259815 0.993200985245429 GO:0035403 histone H3T6 kinase activity 3/442 247/18639 0.0121457489878543 0.512182387747999 0.934830587214565 0.993200985245429 GO:0004679 AMP-activated protein kinase activity 3/442 248/18639 0.0120967741935484 0.510117136184499 0.935955971686615 0.993200985245429 GO:1990782 protein tyrosine kinase binding 1/442 117/18639 0.00854700854700855 0.360424643230073 0.940203745179012 0.996185342220205 GO:0061659 ubiquitin-like protein ligase activity 5/442 372/18639 0.0134408602150538 0.566796817982776 0.942596170817643 0.997197778273544 GO:0004519 endonuclease activity 1/442 127/18639 0.0078740157480315 0.332044750062351 0.953037236705388 0.997864096808869 GO:0016757 glycosyltransferase activity 3/442 267/18639 0.0112359550561798 0.47381666581931 0.954202576438194 0.997864096808869 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 3/442 268/18639 0.0111940298507463 0.472048693185655 0.955013727725308 0.997864096808869 GO:0008514 organic anion transmembrane transporter activity 3/442 269/18639 0.0111524163568773 0.470293865329947 0.955811448591347 0.997864096808869 GO:0005216 monoatomic ion channel activity 6/442 448/18639 0.0133928571428571 0.564772543632838 0.956766991042383 0.997864096808869 GO:0005262 calcium channel activity 1/442 131/18639 0.00763358778625954 0.321905979068081 0.957364688217387 0.997864096808869 GO:0005096 GTPase activator activity 3/442 271/18639 0.011070110701107 0.466823061895777 0.95736739427323 0.997864096808869 GO:1901681 sulfur compound binding 3/442 275/18639 0.0109090909090909 0.460032908268202 0.960326735444861 0.997864096808869 GO:0004518 nuclease activity 2/442 209/18639 0.00956937799043062 0.403537638831756 0.960457061908154 0.997864096808869 GO:0001217 DNA-binding transcription repressor activity 3/442 278/18639 0.0107913669064748 0.455068524366028 0.962418689176599 0.997864096808869 GO:0070851 growth factor receptor binding 1/442 139/18639 0.00719424460431655 0.303379016244018 0.964862287532711 0.997864096808869 GO:0019903 protein phosphatase binding 1/442 144/18639 0.00694444444444444 0.292845022624434 0.968864392836032 0.997864096808869 GO:0015085 calcium ion transmembrane transporter activity 1/442 147/18639 0.00680272108843537 0.286868593591283 0.97104385426417 0.997864096808869 GO:0019842 vitamin binding 1/442 150/18639 0.00666666666666667 0.281131221719457 0.973071076490927 0.997864096808869 GO:0000510 H3-H4 histone complex chaperone activity 1/442 151/18639 0.00662251655629139 0.279269425549129 0.973714842199782 0.997864096808869 GO:0140584 chromatin extrusion motor activity 1/442 151/18639 0.00662251655629139 0.279269425549129 0.973714842199782 0.997864096808869 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/442 151/18639 0.00662251655629139 0.279269425549129 0.973714842199782 0.997864096808869 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/442 151/18639 0.00662251655629139 0.279269425549129 0.973714842199782 0.997864096808869 GO:0015616 DNA translocase activity 1/442 152/18639 0.00657894736842105 0.277432126696833 0.974343251965451 0.997864096808869 GO:0140674 ATP-dependent histone chaperone activity 1/442 152/18639 0.00657894736842105 0.277432126696833 0.974343251965451 0.997864096808869 GO:0061775 cohesin loader activity 1/442 153/18639 0.0065359477124183 0.275618844822997 0.974956671267191 0.997864096808869 GO:0005125 cytokine activity 2/442 234/18639 0.00854700854700855 0.360424643230073 0.97627050656361 0.997864096808869 GO:0140658 ATP-dependent chromatin remodeler activity 1/442 158/18639 0.00632911392405063 0.266896729480497 0.977811106421908 0.997864096808869 GO:0003689 DNA clamp loader activity 1/442 160/18639 0.00625 0.263560520361991 0.978859801813125 0.997864096808869 GO:0140713 histone chaperone activity 1/442 164/18639 0.00609756097560976 0.257132214987308 0.980811149568541 0.997864096808869 GO:0016874 ligase activity 1/442 167/18639 0.00598802395209581 0.25251307340071 0.982155769032317 0.997864096808869 GO:1901981 phosphatidylinositol phosphate binding 1/442 185/18639 0.00540540540540541 0.227944233826587 0.988463286212301 0.997864096808869 GO:0046943 carboxylic acid transmembrane transporter activity 1/442 188/18639 0.00531914893617021 0.224306825839992 0.989272595626856 0.997864096808869 GO:0140597 protein carrier chaperone 1/442 188/18639 0.00531914893617021 0.224306825839992 0.989272595626856 0.997864096808869 GO:0005342 organic acid transmembrane transporter activity 1/442 189/18639 0.00529100529100529 0.223120017237664 0.989529574258525 0.997864096808869 GO:0019902 phosphatase binding 1/442 190/18639 0.00526315789473684 0.221945701357466 0.98978041047412 0.997864096808869 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 5/442 484/18639 0.0103305785123967 0.435637223738828 0.990428619215286 0.997864096808869 GO:0001216 DNA-binding transcription activator activity 5/442 491/18639 0.010183299389002 0.429426509754771 0.991502529156876 0.997864096808869 GO:0106310 protein serine kinase activity 3/442 361/18639 0.00831024930747922 0.350440581090736 0.992112718729279 0.997864096808869 GO:0140098 catalytic activity, acting on RNA 3/442 387/18639 0.00775193798449612 0.326896769441229 0.99526295338404 0.998859041963497 GO:0022836 gated channel activity 2/442 318/18639 0.00628930817610063 0.265218133697601 0.995980485646599 0.998859041963497 GO:0005261 monoatomic cation channel activity 2/442 341/18639 0.00586510263929619 0.247329520574302 0.997558835985919 0.998998314825726 GO:0046873 metal ion transmembrane transporter activity 1/442 450/18639 0.00222222222222222 0.093710407239819 0.999982151145199 0.999982151145199