category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	34/204	238/9376	6.56582633053221	RPL3/FOS/JUN/RPS26/RPS3/RPL7A/RPS10/RPL27A/RPL36AL/NFKBIA/RPL9/RPS2/RPS4Y1/RPS14/RPL19/RPS25/RPL8/RPS3A/RPL36A/RPS9/RPS20/RPS6/RPL4/RPL23A/RPS4X/RPL15/RPS12/RPL10A/RPL14/RPL24/RPLP0/ISG15/RPL11/RPS23	12.9706353973225
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	35/204	268/9376	6.00234123500146	MT-ATP6/MT-ND1/MT-CYB/MT-CO3/MT-CO1/DUSP1/UBC/MT-ND4/MT-ND2/MT-CO2/TUBA1A/NDUFA4/TUBA1B/UBB/NDUFS5/PSMB3/PSMB1/MT-ND5/NDUFB5/PSMA2/PARK7/TXN/MT-ND3/PSMB2/TUBB/ADRM1/TUBB4B/NDUFB7/UQCRC2/NDUFS4/COX6B1/SOD1/PSMA5/COX5A/PSMA7	12.3907586779941
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	40/204	368/9376	4.99573742540494	MT-ATP6/MT-ND1/MT-CYB/MT-CO3/MT-CO1/HNRNPA1/ACTG1/MT-ND4/MT-ND2/MT-CO2/SRSF7/TUBA1A/RAC1/NDUFA4/TUBA1B/NDUFS5/PSMB3/PSMB1/GPX1/MT-ND5/NDUFB5/PSMA2/SRSF3/MT-ND3/PSMB2/TUBB/ADRM1/TUBB4B/NDUFB7/UQCRC2/GPX3/NDUFS4/COX6B1/SOD1/HNRNPA2B1/DCTN3/PSMA5/COX5A/RAB8A/PSMA7	11.6620624002229
Genetic Information Processing	Translation	hsa03010	Ribosome	31/204	222/9376	6.41794735912383	RPL3/RPS26/RPS3/RPL7A/RPS10/RPL27A/RPL36AL/RPL9/RPS2/RPS4Y1/RPS14/RPL19/RPS25/RPL8/RPS3A/RPL36A/RPS9/RPS20/RPS6/RPL4/RPL23A/RPS4X/RPL15/RPS12/RPL10A/RPL14/RPL24/MRPL11/RPLP0/RPL11/RPS23	12.1835686060775
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	33/204	275/9376	5.51529411764706	MT-ATP6/MT-ND1/MT-CYB/MT-CO3/MT-CO1/MT-ND4/MT-ND2/MT-CO2/TUBA1A/RAC1/NDUFA4/TUBA1B/NDUFS5/PSMB3/PSMB1/MT-ND5/NDUFB5/PSMA2/MT-ND3/PSMB2/EGR1/TUBB/ADRM1/TUBB4B/NDUFB7/CYBA/UQCRC2/NDUFS4/COX6B1/SOD1/PSMA5/COX5A/PSMA7	11.3338258003993
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	34/204	308/9376	5.07359307359307	MT-ATP6/MT-ND1/MT-CYB/MT-CO3/MT-CO1/MT-ND4/MT-ND2/MT-CO2/TUBA1A/NDUFA4/TUBA1B/NDUFS5/PSMB3/PSMB1/GPX1/MT-ND5/NDUFB5/PSMA2/MT-ND3/PSMB2/TUBB/ADRM1/TUBB4B/SOD2/NDUFB7/UQCRC2/GPX3/NDUFS4/COX6B1/SOD1/DCTN3/PSMA5/COX5A/PSMA7	10.8409151414292
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	27/204	227/9376	5.46670121793211	FOS/JUN/MT-ATP6/MT-ND1/MT-CYB/MT-CO3/MT-CO1/MT-ND4/NFKBIA/MT-ND2/MT-CO2/RAC1/NDUFA4/NDUFS5/MT-ND5/MGST3/NDUFB5/GSTO1/MT-ND3/SOD2/NDUFB7/CYBA/UQCRC2/NDUFS4/COX6B1/SOD1/COX5A	10.1597194783468
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	38/204	480/9376	3.63856209150327	MT-ATP6/MT-ND1/MT-CYB/MT-CO3/MT-CO1/UBC/MT-ND4/MT-ND2/MT-CO2/TUBA1A/RAC1/NDUFA4/TUBA1B/UBB/NDUFS5/PSMB3/PSMB1/GPX1/MT-ND5/NDUFB5/PSMA2/PARK7/MT-ND3/PSMB2/TUBB/ADRM1/TUBB4B/NDUFB7/UQCRC2/GPX3/NDUFS4/COX6B1/SOD1/DCTN3/PSMA5/COX5A/RAB8A/PSMA7	8.8503256108084
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	20/204	138/9376	6.66098323387326	MT-ATP6/MT-ND1/MT-CYB/MT-CO3/MT-CO1/MT-ND4/MT-ND2/MT-CO2/NDUFA4/NDUFS5/ATP6V1G1/MT-ND5/NDUFB5/ATP6V0E1/MT-ND3/NDUFB7/UQCRC2/NDUFS4/COX6B1/COX5A	9.99104998554924
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	22/204	205/9376	4.9323768531803	MT-ATP6/MT-ND1/MT-CYB/MT-CO3/MT-CO1/MT-ND4/MT-ND2/MT-CO2/GAPDH/RAC1/NDUFA4/NDUFS5/MT-ND5/NDUFB5/MT-ND3/NDUFB7/CYBA/UQCRC2/NDUFS4/COX6B1/PPP1CA/COX5A	8.48970136636873
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	30/204	388/9376	3.55366889023651	MT-ATP6/MT-ND1/MT-CYB/MT-CO3/MT-CO1/MT-ND4/MT-ND2/MT-CO2/GAPDH/TUBA1A/NDUFA4/TUBA1B/NDUFS5/PSMB3/PSMB1/MT-ND5/NDUFB5/PSMA2/MT-ND3/PSMB2/TUBB/ADRM1/TUBB4B/NDUFB7/UQCRC2/NDUFS4/COX6B1/PSMA5/COX5A/PSMA7	7.66156720756867
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	11/204	46/9376	10.9906223358909	PSMB3/PSMB1/PSMA2/PSMB8/PSMB2/POMP/ADRM1/PSME2/PSMA5/PSMB9/PSMA7	10.1297641765568
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	21/204	235/9376	4.10713391739675	MT-ATP6/MT-ND1/MT-CYB/MT-CO3/MT-CO1/ACTG1/MT-ND4/MT-ND2/MT-CO2/COX14/NDUFA4/RPS6/NDUFS5/MT-ND5/NDUFB5/MT-ND3/NDUFB7/UQCRC2/NDUFS4/COX6B1/COX5A	7.19392237456772
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	16/204	157/9376	4.68390158611215	FOS/JUN/MT-CYB/MT-CO3/MT-CO1/MT-CO2/RAC1/NDUFA4/NDUFS5/NDUFB5/SOCS3/NDUFB7/UQCRC2/NDUFS4/COX6B1/COX5A	6.942000446763
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	20/204	248/9376	3.70651486401012	FOS/JUN/RPS3/ACTG1/NFKBIA/GAPDH/MYL12B/TUBA1A/RAC1/TUBA1B/TXN/TUBB/TUBB4B/ARPC1B/ANXA2/MYL12A/DCTN3/DYNLT1/ARF6/S100A10	6.44194689212863
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	13/204	155/9376	3.85477545857053	HLA-A/HLA-C/ACTG1/HLA-E/TUBA1A/RAC1/TUBA1B/ATP6V1G1/ATP6V0E1/TUBB/TUBB4B/CYBA/HLA-F	5.34462811101245
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	8/204	59/9376	6.23197075440346	GPX1/MGST3/GSTO1/PRDX6/GSTK1/GPX3/GSTP1/IDH2	6.01204142927975
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	14/204	200/9376	3.21725490196078	FOS/JUN/RPS3/ACTG1/NFKBIA/GAPDH/TUBA1A/RAC1/TUBA1B/TUBB/TUBB4B/ARPC1B/ARF6/TMBIM6	4.72685867668635
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	14/204	205/9376	3.13878527020564	JUN/HLA-A/HLA-C/NFKBIA/GADD45B/B2M/HLA-E/TNFAIP3/RAC1/VIM/CCND3/ISG15/ADRM1/HLA-F	4.61747408978598
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	11/204	142/9376	3.56034244683789	FOS/JUN/KLF2/DUSP1/ACTG1/RAC1/MGST3/GSTO1/TXN/CYBA/GSTP1	4.58475351589122
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	14/204	224/9376	2.87254901960784	FOS/JUN/HLA-A/HLA-C/NFKBIA/B2M/HLA-E/ZFP36/RAN/CCND3/EGR1/ANAPC16/HLA-F/RANBP1	4.23026815316697
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	10/204	142/9376	3.23667495167081	FOS/JUN/JUNB/JUND/NFKBIA/FOSB/RAC1/SOCS3/SOCS1/CYBA	4.00516866845033
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	10/204	149/9376	3.08461639689433	MT-ND1/MT-ND4/MT-ND2/NDUFA4/NDUFS5/MT-ND5/NDUFB5/MT-ND3/NDUFB7/NDUFS4	3.82523148941234
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	11/204	180/9376	2.80871459694989	HLA-A/HLA-C/NFKBIA/B2M/HLA-E/SRSF7/SRSF3/SOCS3/PPP1CA/SRSF5/HLA-F	3.65405864884663
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	7/204	83/9376	3.87621072525396	PRDX1/PRDX5/GSTK1/SOD2/ECH1/SOD1/IDH2	3.92509775988792
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	7/204	87/9376	3.69799414018481	MT-CYB/MT-CO3/MT-CO1/MT-CO2/UQCRC2/COX6B1/COX5A	3.77037759345081
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	13/204	253/9376	2.36162132837325	JUN/UBC/ACTG1/NFKBIA/MYL12B/RAC1/UBB/UBE2N/UBE2D3/ARPC1B/UBE2D2/MYL12A/ARF6	3.27428491753921
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	11/204	196/9376	2.57943177270908	FOS/JUN/HLA-A/HLA-C/UBC/NFKBIA/HLA-E/RAC1/ZFP36/UBB/HLA-F	3.33254685500504
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	8/204	116/9376	3.16970926301555	ALDOA/GAPDH/MDH2/PKM/GCSH/IDH2/MDH1/ENO1	3.50666067673523
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	10/204	170/9376	2.70357554786621	JUN/ACTG1/MYL12B/TUBA1A/RAC1/TUBA1B/ARPC1B/RAP1A/MYL12A/RAB8A	3.34286680082513
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	6/204	70/9376	3.93949579831933	HLA-A/HLA-C/ACTG1/HLA-E/RAC1/HLA-F	3.68136635227332
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	11/204	205/9376	2.46618842659015	JUN/HLA-A/HLA-C/NFKBIA/HLA-E/RAC1/CCND3/PKM/DDX3X/HLA-F/RANBP1	3.16538886106745
Genetic Information Processing	Transcription	hsa03040	Spliceosome	12/204	243/9376	2.26966836117163	HNRNPA1/SRSF7/SNRPD2/SRSF3/MAGOH/SNRPD1/SRSF5/SNRPF/LSM2/LSM6/SNRPC/SNU13	2.99057986119688
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	6/204	78/9376	3.53544494720965	BTG1/BTG2/TOB1/LSM2/LSM6/ENO1	3.35332320558218
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	6/204	82/9376	3.36298421807747	HLA-A/HLA-C/B2M/HLA-E/PSME2/HLA-F	3.20505223617804
Human Diseases	Immune disease	hsa05330	Allograft rejection	4/204	39/9376	4.71392659627954	HLA-A/HLA-C/HLA-E/HLA-F	3.46601660410939
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	8/204	142/9376	2.58933996133665	UBC/UBB/SOCS3/UBE2N/UBE2D3/SOCS1/ANAPC16/UBE2D2	2.84599897356854
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	7/204	116/9376	2.77349560513861	CXCR4/ACTG1/MYL12B/RAC1/CYBA/RAP1A/MYL12A	2.86630444221767
NA	NA	hsa04517	IgSF CAM signaling	13/204	299/9376	1.99829497016198	ACTG1/CD48/MYL12B/TUBA1A/RAC1/TUBA1B/ICAM3/TUBB/TUBB4B/ARPC1B/RAP1A/MYL12A/ARF6	2.61632691090278
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	4/204	44/9376	4.17825311942959	HLA-A/HLA-C/HLA-E/HLA-F	3.15134647246216
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	7/204	119/9376	2.70357554786621	FOS/JUN/JUNB/NFKBIA/TNFAIP3/IRF1/SOCS3	2.78912799985333
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	5/204	67/9376	3.42990927714369	ALDOA/GAPDH/LDHA/PKM/ENO1	2.97676564074095
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	4/204	45/9376	4.08540305010893	HLA-A/HLA-C/HLA-E/HLA-F	3.09401749855917
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	6/204	94/9376	2.93366708385482	FOS/JUN/JUND/NFKBIA/FOSB/TNFAIP3	2.80991736419241
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	10/204	214/9376	2.14770020157596	FOS/JUN/CXCR4/HLA-A/HLA-C/NFKBIA/B2M/HLA-E/RAC1/HLA-F	2.53284666938401
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	4/204	47/9376	3.91155611180643	LDHA/MDH2/PKM/MDH1	2.98418158183003
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	5/204	71/9376	3.23667495167081	JUN/NFKBIA/RAC1/ATP6V1G1/ATP6V0E1	2.82125640895271
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	8/204	157/9376	2.34195079305608	HLA-A/HLA-C/GADD45B/HLA-E/ZFP36L2/CCND3/PPP1CA/HLA-F	2.52879258231239
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	5/204	75/9376	3.0640522875817	ALDOA/GAPDH/PKM/IDH2/ENO1	2.67642577252329
Cellular Processes	Cell motility	hsa04814	Motor proteins	9/204	194/9376	2.1322013341419	ACTG1/MYL12B/TUBA1A/TUBA1B/TUBB/TUBB4B/MYL12A/DCTN3/DYNLT1	2.37642756868665
Metabolism	Carbohydrate metabolism	hsa00020	Citrate cycle (TCA cycle)	3/204	30/9376	4.59607843137255	MDH2/IDH2/MDH1	2.94201981288393
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	5/204	78/9376	2.94620412267471	FOS/JUN/EEF1A1/NFKBIA/CYBA	2.57400637097137
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	3/204	31/9376	4.44781783681214	MDH2/GCSH/MDH1	2.86750513995155
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	4/204	54/9376	3.40450254175744	HLA-A/HLA-C/HLA-E/HLA-F	2.64262944662659
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	7/204	137/9376	2.34836124230714	FOS/JUN/ACTG1/NFKBIA/GADD45B/TUBA1A/TUBA1B	2.37095198736663
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	7/204	138/9376	2.33134413185564	FOS/JUN/ACTG1/NFKBIA/RAC1/ARPC1B/ARF6	2.34968471373416
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	5/204	82/9376	2.8024868483979	CMPK1/MGST3/GSTO1/DUT/GSTP1	2.444817218813
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	7/204	144/9376	2.23420479302832	PSMB3/PSMB1/PSMA2/PSMB2/ADRM1/PSMA5/PSMA7	2.22581608061039
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	5/204	93/9376	2.47100990934008	ACTG1/MYL12B/RAC1/RAP1A/MYL12A	2.1260897624038
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	5/204	95/9376	2.41898864809082	FOS/JUN/LTB/ATP6V1G1/ATP6V0E1	2.07306078459148
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	4/204	69/9376	2.6643932935493	FOS/JUN/FOSB/PPP1CA	2.06939952225377
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	4/204	70/9376	2.62633053221289	MGST3/GSTO1/GSTK1/GSTP1	2.03678416631398
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	4/204	71/9376	2.58933996133665	FOS/IRF1/SOCS3/SOCS1	2.00473276126964
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	4/204	73/9376	2.51839914047811	MGST3/GSTO1/GSTK1/GSTP1	1.9422474847813
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	8/204	203/9376	1.81126243600889	JUN/ACTG1/MYL12B/RAC1/CCND3/PPP1CA/RAP1A/MYL12A	1.74269902547134
Human Diseases	Infectious disease: viral	hsa05162	Measles	6/204	136/9376	2.02768166089965	FOS/JUN/NFKBIA/TNFAIP3/EIF3H/CCND3	1.8003658812243
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	3/204	47/9376	2.93366708385482	SOCS3/PKM/SOCS1	1.98190021948448
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	7/204	174/9376	1.8489970700924	DNAJB1/ERP29/UBXN1/PPP1R15A/UBE2D3/UBE2D2/SSR2	1.68580912413728
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	5/204	110/9376	2.0891265597148	ALDOA/GAPDH/LDHA/RPS6/ENO1	1.7135518197254
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	4/204	79/9376	2.3271283196823	MGST3/GSTO1/GSTK1/GSTP1	1.76654109862774
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	9/204	250/9376	1.65458823529412	CXCR4/HLA-A/HLA-C/HLA-E/CHMP5/ARPC1B/ARF6/RAB8A/HLA-F	1.5644679358668
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	3/204	51/9376	2.70357554786621	ACTG1/ATP6V1G1/ATP6V0E1	1.81924321778397
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	5/204	115/9376	1.99829497016198	FOS/JUND/NACA/SGK1/EGR1	1.60637730554829
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	3/204	54/9376	2.55337690631808	LDHA/MDH2/MDH1	1.70721364733744
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	4/204	85/9376	2.16286043829296	CMPK1/DUT/DGUOK/GUK1	1.60610719383163
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	4/204	87/9376	2.11313950867703	FOS/JUN/GADD45B/RAC1	1.55558390560969
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	8/204	227/9376	1.61976332383174	CXCR4/HLA-A/HLA-C/NFKBIA/B2M/HLA-E/RAC1/HLA-F	1.40968047914637
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	2/204	28/9376	3.28291316526611	ATP6V1G1/ATP6V0E1	1.80417123917315
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	4/204	89/9376	2.06565322758317	TUBA1A/TUBA1B/TUBB/TUBB4B	1.50640547025493
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	8/204	232/9376	1.58485463150778	CXCR4/ACTG1/MYL12B/RAC1/TMSB4X/ARPC1B/PPP1CA/MYL12A	1.34521752374593
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	4/204	91/9376	2.02025425554837	FOS/JUN/NFKBIA/RAC1	1.45850141878705
Organismal Systems	Immune system	hsa04611	Platelet activation	5/204	126/9376	1.82384064737006	ACTG1/MYL12B/PPP1CA/RAP1A/MYL12A	1.38843745492878
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	5/204	133/9376	1.72784903435058	KLF2/GADD45B/SGK1/SOD2/CDKN2D	1.26075109202315
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	5/204	133/9376	1.72784903435058	HLA-A/HLA-C/CD48/HLA-E/RAC1	1.26075109202315
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/204	101/9376	1.8202290817317	JUN/RAC1/EGR1/PIM1	1.23596903392265
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	4/204	103/9376	1.78488482771749	SAP18/MAGOH/SSU72/PPP1CA	1.19449164215626
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	10/204	333/9376	1.38020373314491	HLA-A/HLA-C/HLA-E/ATP6V1G1/IRF1/CCND3/ATP6V0E1/PKM/ISG15/HLA-F	1.05353975207788
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	7/204	216/9376	1.48946986201888	FOS/JUN/NFKBIA/RAC1/SOD2/CYBA/RAP1A	1.08535995479394
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	4/204	105/9376	1.75088702147526	NFKBIA/GADD45B/LTB/TNFAIP3	1.15391722373004
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	4/204	105/9376	1.75088702147526	JUN/UBC/UBB/TOMM20	1.15391722373004
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	3/204	70/9376	1.96974789915966	JUN/RAC1/RAP1A	1.21449307333431
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	3/204	71/9376	1.94200497100249	LDHA/PKM/IDH2	1.18820911358658
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	3/204	72/9376	1.91503267973856	NFKBIA/ISG15/DDX3X	1.16234941427133
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	4/204	108/9376	1.70225127087872	EEF1A1/SAP18/RAN/MAGOH	1.09466214016484
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	4/204	109/9376	1.68663428674222	FOS/JUN/NFKBIA/RAC1	1.07532031911579
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	6/204	187/9376	1.47467757156338	JUN/NFKBIA/TNFAIP3/TXN/GBP2/CYBA	0.977809130469161
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	3/204	75/9376	1.83843137254902	MGST3/GSTO1/GSTP1	1.08718143793315
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/204	42/9376	2.18860877684407	SAT1/FTH1	1.15132617585313
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	3/204	78/9376	1.76772247360483	ACTG1/RAC1/ARPC1B	1.01537270174975
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/204	78/9376	1.76772247360483	FOS/JUN/IRF1	1.01537270174975
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	3/204	79/9376	1.74534623976173	ATP6V1G1/ATP6V0E1/VAMP2	0.99213071239557
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	5/204	158/9376	1.45445519980144	DDIT4/EIF4B/RPS6/ATP6V1G1/SGK1	0.859151924754457
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	4/204	120/9376	1.53202614379085	JUN/NFKBIA/RAC1/RAP1A	0.874743296516555
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	5/204	160/9376	1.43627450980392	HLA-A/HLA-C/HLA-E/ICAM3/HLA-F	0.830074927964083
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	4/204	122/9376	1.50691096110575	FOS/JUNB/SOCS3/SOCS1	0.840457097087123
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	6/204	204/9376	1.3517877739331	ACTG1/RAC1/EIF4B/RPS6/CD63/PPP1CA	0.757586978651947
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	2/204	49/9376	1.87595038015206	JUN/FOSB	0.916801374975471
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	5/204	169/9376	1.35978651815756	UBC/DDIT4/UBB/IGBP1/RAB8A	0.703878767874452
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	5/204	170/9376	1.3517877739331	ACTG1/GADD45B/MGST3/GSTO1/GSTP1	0.690300862729631
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/204	90/9376	1.53202614379085	FOS/JUN/NFKBIA	0.756325229805236
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	5/204	173/9376	1.32834636744871	ACTG1/NFKBIA/DNAJB1/SOCS3/CCND3	0.650068699414303
Organismal Systems	Digestive system	hsa04980	Cobalamin transport and metabolism	1/204	18/9376	2.55337690631808	PRDX1	0.983762526357176
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	8/204	300/9376	1.22562091503268	FOS/JUN/JUND/DUSP1/GADD45B/DUSP2/RAC1/RAP1A	0.592326876371966
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	3/204	93/9376	1.48260594560405	FOS/JUN/NFKBIA	0.697523214295871
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	6/204	217/9376	1.27080509623204	FOS/JUN/MGST3/GSTO1/CCND3/PTGES3	0.601909737557705
Metabolism	Metabolism of cofactors and vitamins	hsa00785	Lipoic acid metabolism	1/204	19/9376	2.41898864809082	GCSH	0.923328212519213
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	2/204	56/9376	1.64145658263305	EEF1A1/NFKBIA	0.717995996147912
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	4/204	138/9376	1.33219664677465	RPS6/SOCS3/SOCS1/PPP1CA	0.586292727930679
Metabolism	Glycan biosynthesis and metabolism	hsa00541	Biosynthesis of various nucleotide sugars	1/204	20/9376	2.29803921568627	UGP2	0.866615402368112
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	4/204	139/9376	1.3226124982367	FOS/JUN/KRT19/KRT18	0.571467866908052
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	3/204	98/9376	1.40696278511405	RAC1/ARPC1B/ARF6	0.603961492176483
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	3/204	99/9376	1.39275103980986	FOS/JUN/RAC1	0.585868113075941
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	2/204	59/9376	1.55799268860086	CMPK1/DUT	0.641187674506809
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	6/204	226/9376	1.22019781363873	FOS/JUN/NFKBIA/RAC1/PPP1CA/RAP1A	0.49971843815262
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	3/204	102/9376	1.3517877739331	RAC1/RAP1A/RAB8A	0.532740827375517
Organismal Systems	Digestive system	hsa04978	Mineral absorption	2/204	61/9376	1.50691096110575	MT2A/FTH1	0.592343829858698
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/204	103/9376	1.33866362078812	FOS/JUN/NFKBIA	0.515401559882606
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	2/204	62/9376	1.48260594560405	SOD2/SOD1	0.568576747546687
Organismal Systems	Excretory system	hsa04964	Proximal tubule bicarbonate reclamation	1/204	23/9376	1.99829497016198	MDH1	0.714851828982537
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	3/204	105/9376	1.31316526610644	JUN/NFKBIA/IRF1	0.481253216661346
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	3/204	109/9376	1.26497571505666	FOS/JUN/NFKBIA	0.414971661005385
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	3/204	109/9376	1.26497571505666	NFKBIA/SOCS3/PPP1CA	0.414971661005385
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	2/204	67/9376	1.37196371085748	PPP1CA/RAP1A	0.455674952352372
NA	NA	hsa04518	Integrin signaling	4/204	154/9376	1.19378660555131	ACTG1/RAC1/ICAM3/CCND3	0.361609853345091
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	4/204	154/9376	1.19378660555131	FOS/JUN/ACTG1/PPP1CA	0.361609853345091
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	4/204	158/9376	1.16356415984115	GADD45B/CCND3/ANAPC16/CDKN2D	0.309219616828611
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	2/204	70/9376	1.31316526610644	NFKBIA/SOCS3	0.392201980354638
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	2/204	73/9376	1.25919957023905	CXCR4/RAN	0.331552949374484
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	4/204	163/9376	1.12787200769879	FOS/JUN/NFKBIA/DDX3X	0.245605138919748
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/204	75/9376	1.22562091503268	GADD45B/CCND3	0.292559270638075
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	2/204	75/9376	1.22562091503268	GPX1/GPX3	0.292559270638075
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/204	31/9376	1.48260594560405	ALDOA	0.401377072423965
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/204	31/9376	1.48260594560405	SPCS2	0.401377072423965
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	2/204	76/9376	1.20949432404541	UBC/PLIN2	0.273467853385512
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	3/204	122/9376	1.13018322082932	FOS/JUN/NFKBIA	0.215843452327384
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	4/204	168/9376	1.09430438842204	SOCS3/CCND3/SOCS1/PIM1	0.183938477489742
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	2/204	77/9376	1.19378660555131	GADD45B/RAC1	0.254635935298722
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	2/204	77/9376	1.19378660555131	NFKBIA/GADD45B	0.254635935298722
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	1/204	32/9376	1.43627450980392	UGP2	0.36866941717884
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/204	32/9376	1.43627450980392	LDHA	0.36866941717884
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/204	32/9376	1.43627450980392	IGBP1	0.36866941717884
NA	NA	hsa04382	Cornified envelope formation	5/204	217/9376	1.05900424686003	KRT19/KRT18/KRT8/S100A4/S100A10	0.131146833041435
Metabolism	Global and overview maps	hsa01210	2-Oxocarboxylic acid metabolism	1/204	33/9376	1.39275103980986	IDH2	0.337054273495113
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/204	33/9376	1.39275103980986	VAMP2	0.337054273495113
NA	NA	hsa04519	Cadherin signaling	9/204	404/9376	1.02387885847408	ACTG1/NFKBIA/KRT19/RAC1/VIM/KRT18/KRT8/ARPC1B/PPP1CA	0.0731692006518286
Genetic Information Processing	Transcription	hsa03020	RNA polymerase	1/204	34/9376	1.3517877739331	POLR1D	0.306456592118946
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	1/204	35/9376	1.31316526610644	ALDOA	0.276808627807989
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	3/204	130/9376	1.0606334841629	FOS/JUN/NFKBIA	0.103818788150306
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	2/204	83/9376	1.10748877864399	UBE2D3/UBE2D2	0.146687431683696
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	2/204	83/9376	1.10748877864399	NFKBIA/POLR1D	0.146687431683696
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	1/204	36/9376	1.27668845315904	UGP2	0.248049037717255
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/204	36/9376	1.27668845315904	UGP2	0.248049037717255
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	3/204	133/9376	1.03670942061035	FOS/COMT/PPP1CA	0.063586595485875
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/204	37/9376	1.24218335983042	COMT	0.220122113037995
Metabolism	Global and overview maps	hsa01250	Biosynthesis of nucleotide sugars	1/204	37/9376	1.24218335983042	UGP2	0.220122113037995
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/204	37/9376	1.24218335983042	GADD45B	0.220122113037995
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/204	38/9376	1.20949432404541	UGP2	0.192977121144133
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/204	38/9376	1.20949432404541	SGK1	0.192977121144133
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	4/204	184/9376	0.999147485080989	CXCR4/MYL12B/RAC1/MYL12A	-0.00174170496727601
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/204	39/9376	1.17848164906988	GCSH	0.166567739875299
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	3/204	140/9376	0.984873949579832	KLF2/RPS6/EGR1	-0.026891578675201
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/204	41/9376	1.12099473935916	GCSH	0.11578970686335
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/204	93/9376	0.988403963736032	JUN/EGR1	-0.016760059758092
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/204	93/9376	0.988403963736032	NFKBIA/GADD45B	-0.016760059758092
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	4/204	193/9376	0.952555115310373	CXCR4/NFKBIA/RAC1/RAP1A	-0.0993217714257441
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	1/204	44/9376	1.0445632798574	TAF7	0.0441860133547694
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/204	44/9376	1.0445632798574	VAMP2	0.0441860133547694
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	3/204	148/9376	0.931637519872814	FOS/JUN/GADD45B	-0.125015416983244
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/204	46/9376	0.999147485080989	FTH1	-0.000864388102786719
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	2/204	99/9376	0.928500693206576	FOS/JUN	-0.106655768441964
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/204	99/9376	0.928500693206576	KRT19/KRT18	-0.106655768441964
NA	NA	hsa03272	Virion - Hepatitis viruses	1/204	48/9376	0.957516339869281	CD63	-0.0440065147739627
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/204	103/9376	0.892442413858747	PRDX1/SERPINB9	-0.163688522391047
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/204	50/9376	0.91921568627451	SAT1	-0.0854147817310169
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/204	50/9376	0.91921568627451	CXCR4	-0.0854147817310169
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	3/204	157/9376	0.878231547396028	DUSP2/RAC1/SGK1	-0.229462332969249
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	3/204	157/9376	0.878231547396028	ACTG1/CCND3/PPP1CA	-0.229462332969249
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	2/204	106/9376	0.867184609692934	NFKBIA/GSTP1	-0.205083238732415
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	2/204	107/9376	0.859080080630383	LDHA/PKM	-0.218633412110331
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	2/204	112/9376	0.820728291316527	NFKBIA/SOCS1	-0.28463624070986
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	3/204	168/9376	0.820728291316527	TNFAIP3/FTH1/CHMP5	-0.349665224534956
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/204	59/9376	0.778996344300432	GADD45B	-0.253954617955347
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/204	60/9376	0.766013071895425	RAC1	-0.271157224527564
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	3/204	178/9376	0.774619960343688	JUN/RAC1/CCND3	-0.452738521648281
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/204	63/9376	0.729536258948024	PTGES3	-0.321220477264011
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/204	63/9376	0.729536258948024	GADD45B	-0.321220477264011
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	4/204	233/9376	0.789026340149794	ACTG1/VIM/CSRP2/ENO1	-0.486329413039907
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/204	66/9376	0.696375519904932	COMT	-0.369149776930118
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/204	66/9376	0.696375519904932	JUN	-0.369149776930118
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/204	128/9376	0.718137254901961	DGUOK/GUK1	-0.478836723507474
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/204	68/9376	0.675893886966551	PIM1	-0.400020446585296
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/204	69/9376	0.666098323387326	RAC1	-0.415151859082837
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	4/204	250/9376	0.735372549019608	ATP6V1G1/ATP6V0E1/CD63/LAPTM5	-0.632460438007979
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/204	73/9376	0.629599785119527	GADD45B	-0.473794318328925
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/204	73/9376	0.629599785119527	GADD45B	-0.473794318328925
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	3/204	195/9376	0.707088989441931	ACTG1/RAC1/CYBA	-0.616419981404531
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	6/204	362/9376	0.761780955476113	DDIT4/RAC1/EIF4B/RPS6/SGK1/CCND3	-0.689351437688637
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	2/204	138/9376	0.666098323387326	ANAPC16/PPP1CA	-0.589301929271641
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/204	76/9376	0.604747162022704	ACTG1	-0.515951664269218
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/204	76/9376	0.604747162022704	GADD45B	-0.515951664269218
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/204	143/9376	0.642808172219937	SSB/SNRPD1	-0.641899169679647
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/204	80/9376	0.574509803921569	RPS6	-0.569974193332181
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	3/204	212/9376	0.6503884572697	ACTG1/RAC1/RAP1A	-0.767856123266938
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/204	86/9376	0.534427724578203	JUN	-0.64684046093479
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/204	86/9376	0.534427724578203	VAMP2	-0.64684046093479
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/204	86/9376	0.534427724578203	ACTG1	-0.64684046093479
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	2/204	154/9376	0.596893302775656	CMPK1/UGP2	-0.752205516222443
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	2/204	156/9376	0.589240824534942	NFKBIA/SOCS3	-0.771529987929052
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/204	90/9376	0.510675381263617	SOD2	-0.695620993506372
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/204	93/9376	0.494201981868016	VAMP2	-0.731043333812055
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/204	97/9376	0.473822518698201	FOS	-0.776848329881968
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/204	99/9376	0.464250346603288	PPP1CA	-0.799179649959869
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/204	99/9376	0.464250346603288	ACTG1	-0.799179649959869
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/204	100/9376	0.459607843137255	CXCR4	-0.81020956511038
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/204	100/9376	0.459607843137255	CD37	-0.81020956511038
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	3/204	238/9376	0.579337617399901	RAC1/RAP1A/ARF6	-0.980314164698904
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/204	105/9376	0.437721755368814	ACTG1	-0.864074797476036
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	2/204	183/9376	0.502303653701918	RAN/SNU13	-1.0139815812168
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/204	110/9376	0.417825311942959	ANAPC16	-0.915950939971056
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/204	115/9376	0.399658994032396	FOS	-0.966021262653378
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/204	115/9376	0.399658994032396	DUSP1	-0.966021262653378
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/204	191/9376	0.481264757211785	FOSB/PPP1CA	-1.0801686216131
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/204	117/9376	0.392827216356628	ACTG1	-0.985580004451796
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	4/204	323/9376	0.56917379955078	DDIT4/VIM/SOCS1/PIM1	-1.17510265272822
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/204	122/9376	0.376727740276439	RAB8A	-1.03338383719209
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/204	122/9376	0.376727740276439	ACTG1	-1.03338383719209
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/204	125/9376	0.367686274509804	RAC1	-1.06135818622437
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/204	134/9376	0.342990927714369	PPP1CA	-1.14237708376667
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/204	144/9376	0.31917211328976	NFKBIA	-1.22783323069858
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/204	149/9376	0.308461639689433	ARF6	-1.26895975486787
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/204	150/9376	0.30640522875817	GADD45B	-1.27706620927346
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/204	154/9376	0.298446651387828	PPP1CA	-1.30911320100621
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/204	155/9376	0.29652118912081	RAP1A	-1.31703269931051
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/204	166/9376	0.276872194660997	PPP1CA	-1.40187079723869
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/204	201/9376	0.228660618476246	GADD45B	-1.64857684773722
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/204	298/9376	0.308461639689433	CXCR4/LTB	-1.80924765154831
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/204	254/9376	0.180947969739077	CXCR4	-1.97356763491896