ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0045296	cadherin binding	101/2227	334/18639	0.302395209580838	2.53091347614605	1.76816343891887e-19	2.25971287493832e-16
GO:0043021	ribonucleoprotein complex binding	51/2227	177/18639	0.288135593220339	2.41156682623884	1.07114480812298e-09	6.84461532390586e-07
GO:0044389	ubiquitin-like protein ligase binding	74/2227	322/18639	0.229813664596273	1.92343821033226	1.70541322880957e-08	7.26506035472876e-06
GO:0003779	actin binding	93/2227	443/18639	0.209932279909707	1.75703985866054	3.12970643233453e-08	9.99941205130883e-06
GO:0005525	GTP binding	81/2227	378/18639	0.214285714285714	1.79347616909359	9.66403729841291e-08	2.47012793347434e-05
GO:0019001	guanyl nucleotide binding	83/2227	400/18639	0.2075	1.73668275707229	2.87067388722701e-07	5.24103032553731e-05
GO:0032561	guanyl ribonucleotide binding	83/2227	400/18639	0.2075	1.73668275707229	2.87067388722701e-07	5.24103032553731e-05
GO:0043022	ribosome binding	33/2227	112/18639	0.294642857142857	2.46602973250369	5.12115038366018e-07	8.18103773789714e-05
GO:0140297	DNA-binding transcription factor binding	95/2227	488/18639	0.194672131147541	1.62931919733229	8.76040827565134e-07	0.000124397797514249
GO:0031625	ubiquitin protein ligase binding	65/2227	302/18639	0.21523178807947	1.80139438617568	1.4798968098845e-06	0.000189130812303239
GO:0180051	translation factor activity	26/2227	84/18639	0.30952380952381	2.59057668869074	2.92961236868315e-06	0.000340367691561552
GO:0140098	catalytic activity, acting on RNA	77/2227	387/18639	0.198966408268734	1.66526038784056	4.06098495178769e-06	0.000432494897365389
GO:0030515	snoRNA binding	14/2227	32/18639	0.4375	3.66168051189942	6.69302307578641e-06	0.000657975653142695
GO:0008135	translation factor activity, RNA binding	25/2227	83/18639	0.301204819277108	2.52095043848497	7.75596548025318e-06	0.000708008848840255
GO:0061650	ubiquitin-like protein conjugating enzyme activity	16/2227	41/18639	0.390243902439024	3.26616798273955	8.90950384166009e-06	0.000759089727309439
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	33/2227	128/18639	0.2578125	2.15777601594073	1.26288633926995e-05	0.000959081062592342
GO:0019003	GDP binding	23/2227	75/18639	0.306666666666667	2.56666367310283	1.27577293146086e-05	0.000959081062592342
GO:0140517	protein-RNA adaptor activity	11/2227	22/18639	0.5	4.18477772788505	1.38086669047613e-05	0.000980415350238054
GO:0061631	ubiquitin conjugating enzyme activity	14/2227	35/18639	0.4	3.34782218230804	2.32453579063174e-05	0.00154521764293913
GO:0051020	GTPase binding	63/2227	315/18639	0.2	1.67391109115402	2.50337818806176e-05	0.00154521764293913
GO:0005521	lamin binding	9/2227	16/18639	0.5625	4.70787494387068	2.5390900236089e-05	0.00154521764293913
GO:0051015	actin filament binding	46/2227	209/18639	0.220095693779904	1.8421031146671	2.67015759747092e-05	0.00155111882253083
GO:0003925	G protein activity	18/2227	54/18639	0.333333333333333	2.78985181859003	3.16060437267143e-05	0.00175619669055395
GO:0003924	GTPase activity	65/2227	331/18639	0.196374622356495	1.6435682919186	3.39649084859742e-05	0.00180863137687813
GO:0031267	small GTPase binding	57/2227	283/18639	0.201413427561837	1.68574085151553	4.85162086567667e-05	0.00248014858653391
GO:0017124	SH3 domain binding	29/2227	115/18639	0.252173913043478	2.11058354971594	6.40008762278355e-05	0.00310088430682519
GO:0051219	phosphoprotein binding	25/2227	93/18639	0.268817204301075	2.24988049886293	6.55116402850393e-05	0.00310088430682519
GO:0003727	single-stranded RNA binding	24/2227	89/18639	0.269662921348315	2.25695877458969	8.61747407026943e-05	0.00379947620972902
GO:0098641	cadherin binding involved in cell-cell adhesion	9/2227	18/18639	0.5	4.18477772788505	8.62165963084049e-05	0.00379947620972902
GO:0003725	double-stranded RNA binding	21/2227	75/18639	0.28	2.34347552761563	0.000130798900283762	0.00557203315208827
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	65/2227	349/18639	0.186246418338109	1.55879972671936	0.000173008922067302	0.00713243233554878
GO:0001784	phosphotyrosine residue binding	15/2227	47/18639	0.319148936170213	2.67113471992663	0.000245855601784982	0.00961195405411151
GO:0005080	protein kinase C binding	16/2227	52/18639	0.307692307692308	2.57524783254464	0.00024819599670241	0.00961195405411151
GO:0106310	protein serine kinase activity	66/2227	361/18639	0.182825484764543	1.53016803346489	0.000267284859627435	0.0100467661942312
GO:0044183	protein folding chaperone	20/2227	75/18639	0.266666666666667	2.23188145487202	0.000381780543598896	0.0132429795217411
GO:0045309	protein phosphorylated amino acid binding	17/2227	59/18639	0.288135593220339	2.41156682623884	0.000384668218549584	0.0132429795217411
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	6/2227	10/18639	0.6	5.02173327346206	0.000395279438771469	0.0132429795217411
GO:0099122	RNA polymerase II C-terminal domain binding	6/2227	10/18639	0.6	5.02173327346206	0.000395279438771469	0.0132429795217411
GO:0140101	catalytic activity, acting on a tRNA	31/2227	139/18639	0.223021582733813	1.86659150452427	0.000404128483057827	0.0132429795217411
GO:0098632	cell-cell adhesion mediator activity	16/2227	55/18639	0.290909090909091	2.4347797689513	0.000502888296236391	0.0160672810647527
GO:0140662	ATP-dependent protein folding chaperone	13/2227	40/18639	0.325	2.72010552312528	0.000516551084594864	0.0161012752710302
GO:0003713	transcription coactivator activity	49/2227	256/18639	0.19140625	1.60198522395599	0.000547949950776282	0.0163435475168928
GO:1990825	sequence-specific mRNA binding	7/2227	14/18639	0.5	4.18477772788505	0.000549900268565252	0.0163435475168928
GO:0003743	translation initiation factor activity	15/2227	51/18639	0.294117647058824	2.46163395757944	0.000656685283492823	0.0189341171236473
GO:0008173	RNA methyltransferase activity	18/2227	67/18639	0.26865671641791	2.2485372866248	0.000666694264917159	0.0189341171236473
GO:0031072	heat shock protein binding	29/2227	131/18639	0.221374045801527	1.85280235280407	0.000693806429949263	0.0192757525538078
GO:0004857	enzyme inhibitor activity	72/2227	416/18639	0.173076923076923	1.44857690580636	0.000747822907295836	0.0203344186281719
GO:0043175	RNA polymerase core enzyme binding	13/2227	42/18639	0.30952380952381	2.59057668869074	0.000871289679417151	0.0231980877144817
GO:0019887	protein kinase regulator activity	48/2227	255/18639	0.188235294117647	1.57544573285084	0.000905588351174854	0.0234547029728818
GO:0004674	protein serine/threonine kinase activity	74/2227	433/18639	0.170900692840647	1.43036282615932	0.000917633136654216	0.0234547029728818
GO:0140996	histone H3 kinase activity	63/2227	357/18639	0.176470588235294	1.47698037454766	0.000940531020171825	0.0235686008584234
GO:0016866	intramolecular transferase activity	10/2227	28/18639	0.357142857142857	2.98912694848932	0.00099248210166709	0.024392156267895
GO:0035173	histone kinase activity	63/2227	360/18639	0.175	1.46467220475977	0.00116708868336797	0.028142251648005
GO:0141003	histone H2AX kinase activity	62/2227	354/18639	0.175141242937853	1.46585434536086	0.00124503293189551	0.0294657793881938
GO:0019843	rRNA binding	17/2227	65/18639	0.261538461538462	2.18896065766295	0.00128907651649388	0.0299534506923487
GO:0043024	ribosomal small subunit binding	8/2227	20/18639	0.4	3.34782218230804	0.00136720857917974	0.0311557508913267
GO:0019207	kinase regulator activity	52/2227	287/18639	0.181184668989547	1.51643513484336	0.00138957574397936	0.0311557508913267
GO:0008175	tRNA methyltransferase activity	11/2227	34/18639	0.323529411764706	2.70779735333738	0.00143299201514314	0.0315752378509127
GO:0009982	pseudouridine synthase activity	6/2227	13/18639	0.461538461538462	3.86287174881697	0.00234738958162866	0.0502612465960898
GO:0000049	tRNA binding	19/2227	80/18639	0.2375	1.9877694207454	0.00235968293878356	0.0502612465960898
GO:0000993	RNA polymerase II complex binding	11/2227	36/18639	0.305555555555556	2.55736416704086	0.0024022987813696	0.050330128567055
GO:0035402	histone H3T11 kinase activity	45/2227	247/18639	0.182186234817814	1.52481779558564	0.00250860349087352	0.051709600989296
GO:0051059	NF-kappaB binding	10/2227	32/18639	0.3125	2.61548607992815	0.00311958846706386	0.0628804649955127
GO:0043130	ubiquitin binding	22/2227	100/18639	0.22	1.84130220026942	0.00314894347395369	0.0628804649955127
GO:0000287	magnesium ion binding	42/2227	230/18639	0.182608695652174	1.52835360496671	0.00327122675955865	0.0630994213315403
GO:0070063	RNA polymerase binding	15/2227	59/18639	0.254237288135593	2.12785308197545	0.00327179381635588	0.0630994213315403
GO:0070064	proline-rich region binding	7/2227	18/18639	0.388888888888889	3.25482712168837	0.00330802913083975	0.0630994213315403
GO:0008641	ubiquitin-like modifier activating enzyme activity	5/2227	10/18639	0.5	4.18477772788505	0.00363431476595775	0.0645621975301756
GO:0016427	tRNA (cytidine) methyltransferase activity	5/2227	10/18639	0.5	4.18477772788505	0.00363431476595775	0.0645621975301756
GO:0008174	mRNA methyltransferase activity	6/2227	14/18639	0.428571428571429	3.58695233818718	0.0036955065664262	0.0645621975301756
GO:0032036	myosin heavy chain binding	6/2227	14/18639	0.428571428571429	3.58695233818718	0.0036955065664262	0.0645621975301756
GO:0098847	sequence-specific single stranded DNA binding	6/2227	14/18639	0.428571428571429	3.58695233818718	0.0036955065664262	0.0645621975301756
GO:0032182	ubiquitin-like protein binding	25/2227	120/18639	0.208333333333333	1.74365738661877	0.00373310920078379	0.0645621975301756
GO:0042162	telomeric DNA binding	11/2227	38/18639	0.289473684210526	2.42276605298608	0.00384323743779721	0.0645621975301756
GO:0001098	basal transcription machinery binding	15/2227	60/18639	0.25	2.09238886394252	0.0038898976602688	0.0645621975301756
GO:0001099	basal RNA polymerase II transcription machinery binding	15/2227	60/18639	0.25	2.09238886394252	0.0038898976602688	0.0645621975301756
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	15/2227	60/18639	0.25	2.09238886394252	0.0038898976602688	0.0645621975301756
GO:0097718	disordered domain specific binding	9/2227	28/18639	0.321428571428571	2.69021425364039	0.00402816544489716	0.065999941520238
GO:0003697	single-stranded DNA binding	25/2227	121/18639	0.206611570247934	1.72924699499382	0.00418350768624683	0.0666604328995838
GO:0051082	unfolded protein binding	25/2227	121/18639	0.206611570247934	1.72924699499382	0.00418350768624683	0.0666604328995838
GO:0051117	ATPase binding	19/2227	84/18639	0.226190476190476	1.89311373404324	0.00422495701476235	0.0666604328995838
GO:0051087	protein-folding chaperone binding	27/2227	134/18639	0.201492537313433	1.6864029649686	0.00430854437793403	0.0666914924816751
GO:0003712	transcription coregulator activity	79/2227	495/18639	0.15959595959596	1.33574723435523	0.00433129411265965	0.0666914924816751
GO:0016853	isomerase activity	34/2227	180/18639	0.188888888888889	1.58091603053435	0.00443998734541528	0.0675512360409611
GO:0031490	chromatin DNA binding	26/2227	128/18639	0.203125	1.7000659519533	0.0044947358563277	0.0675796755810211
GO:0004722	protein serine/threonine phosphatase activity	22/2227	103/18639	0.213592233009709	1.78767203909652	0.0045962128099054	0.0683018601285942
GO:0048027	mRNA 5'-UTR binding	8/2227	24/18639	0.333333333333333	2.78985181859003	0.00515507265914384	0.0695226267187037
GO:0044325	transmembrane transporter binding	27/2227	136/18639	0.198529411764706	1.66160292136612	0.00530930644483626	0.0695226267187037
GO:0048029	monosaccharide binding	17/2227	74/18639	0.22972972972973	1.92273571281205	0.00559553622747053	0.0695226267187037
GO:0015631	tubulin binding	63/2227	385/18639	0.163636363636364	1.36956362003511	0.00582166739883132	0.0695226267187037
GO:0004177	aminopeptidase activity	11/2227	40/18639	0.275	2.30162775033678	0.00590139694864742	0.0695226267187037
GO:0061791	GTPase motor activity	11/2227	40/18639	0.275	2.30162775033678	0.00590139694864742	0.0695226267187037
GO:1990606	membrane scission GTPase motor activity	11/2227	40/18639	0.275	2.30162775033678	0.00590139694864742	0.0695226267187037
GO:0005536	D-glucose binding	5/2227	11/18639	0.454545454545455	3.80434338898641	0.00601156048558599	0.0695226267187037
GO:0015173	aromatic amino acid transmembrane transporter activity	5/2227	11/18639	0.454545454545455	3.80434338898641	0.00601156048558599	0.0695226267187037
GO:0034511	U3 snoRNA binding	5/2227	11/18639	0.454545454545455	3.80434338898641	0.00601156048558599	0.0695226267187037
GO:0004676	3-phosphoinositide-dependent protein kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0004711	ribosomal protein S6 kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0035175	histone H3S10 kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0035979	histone H2AXS139 kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0044022	histone H3S28 kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0044023	histone H4S1 kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0044024	histone H2AS1 kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0044025	histone H2BS14 kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0072354	histone H3T3 kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0072371	histone H2AS121 kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0072518	Rho-dependent protein serine/threonine kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0140823	histone H2BS36 kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0140855	histone H3S57 kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0140995	histone H2A kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0140997	histone H4 kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0140998	histone H2B kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:1990244	histone H2AT120 kinase activity	43/2227	245/18639	0.175510204081633	1.46894238611475	0.0061471493108087	0.0695226267187037
GO:0031418	L-ascorbic acid binding	7/2227	20/18639	0.35	2.92934440951953	0.00650016407784513	0.0719011300234436
GO:0042288	MHC class I protein binding	7/2227	20/18639	0.35	2.92934440951953	0.00650016407784513	0.0719011300234436
GO:0004677	DNA-dependent protein kinase activity	43/2227	246/18639	0.17479674796748	1.46297107560209	0.00661036268907903	0.0719011300234436
GO:0140857	histone H3T45 kinase activity	43/2227	246/18639	0.17479674796748	1.46297107560209	0.00661036268907903	0.0719011300234436
GO:0008187	poly-pyrimidine tract binding	9/2227	30/18639	0.3	2.51086663673103	0.00669501914928778	0.0719011300234436
GO:0035925	mRNA 3'-UTR AU-rich region binding	9/2227	30/18639	0.3	2.51086663673103	0.00669501914928778	0.0719011300234436
GO:0035403	histone H3T6 kinase activity	43/2227	247/18639	0.174089068825911	1.45704811578184	0.00710261717781308	0.0756428729437093
GO:0061980	regulatory RNA binding	14/2227	58/18639	0.241379310344828	2.02023752380657	0.0072298890769929	0.0763619689289002
GO:0017022	myosin binding	17/2227	76/18639	0.223684210526316	1.87213740458015	0.00740414730358826	0.0769308963738683
GO:0098631	cell adhesion mediator activity	17/2227	76/18639	0.223684210526316	1.87213740458015	0.00740414730358826	0.0769308963738683
GO:0004679	AMP-activated protein kinase activity	43/2227	248/18639	0.173387096774194	1.45117292176659	0.00762529400604443	0.0785897237074579
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	10/2227	36/18639	0.277777777777778	2.32487651549169	0.00788047991721614	0.079301207355923
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	10/2227	36/18639	0.277777777777778	2.32487651549169	0.00788047991721614	0.079301207355923
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	10/2227	36/18639	0.277777777777778	2.32487651549169	0.00788047991721614	0.079301207355923
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	18/2227	83/18639	0.216867469879518	1.81508431570918	0.00831899675501667	0.0830599832258695
GO:0008327	methyl-CpG binding	9/2227	31/18639	0.290322580645161	2.42987093877196	0.00845295480510574	0.0837432266738383
GO:0035198	miRNA binding	11/2227	42/18639	0.261904761904762	2.19202642889217	0.00873917550369853	0.0846870619480487
GO:0051879	Hsp90 protein binding	11/2227	42/18639	0.261904761904762	2.19202642889217	0.00873917550369853	0.0846870619480487
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	42/2227	243/18639	0.172839506172839	1.4465898318615	0.00874702048289704	0.0846870619480487
GO:0004721	phosphoprotein phosphatase activity	32/2227	175/18639	0.182857142857143	1.53043299762653	0.00917250134866864	0.0881387723578836
GO:0031543	peptidyl-proline dioxygenase activity	5/2227	12/18639	0.416666666666667	3.48731477323754	0.00930163093282694	0.0882056632145623
GO:0005085	guanyl-nucleotide exchange factor activity	40/2227	230/18639	0.173913043478261	1.45557486187306	0.00931749963534109	0.0882056632145623
GO:0004860	protein kinase inhibitor activity	18/2227	84/18639	0.214285714285714	1.79347616909359	0.00943555304781332	0.088666447022834
GO:0017069	snRNA binding	13/2227	54/18639	0.240740740740741	2.0148929800928	0.00967659263942336	0.0902677765925771
GO:0048156	tau protein binding	11/2227	43/18639	0.255813953488372	2.14104907008072	0.0105045706728333	0.0969066415894389
GO:0031369	translation initiation factor binding	9/2227	32/18639	0.28125	2.35393747193534	0.0105399242417308	0.0969066415894389
GO:0060590	ATPase regulator activity	12/2227	49/18639	0.244897959183673	2.04968705039268	0.0110340268274635	0.100686120795236
GO:0005092	GDP-dissociation inhibitor activity	6/2227	17/18639	0.352941176470588	2.95396074909533	0.0111085626229485	0.100686120795236
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	14/2227	61/18639	0.229508196721311	1.92088158001281	0.011417154304998	0.102754388744982
GO:0042393	histone binding	42/2227	247/18639	0.17004048582996	1.42316327587994	0.0115021925667516	0.102795818883276
GO:0050660	flavin adenine dinucleotide binding	18/2227	86/18639	0.209302325581395	1.75176742097514	0.0120267380069865	0.106737299812005
GO:0030145	manganese ion binding	15/2227	68/18639	0.220588235294118	1.84622546818458	0.0130183810037986	0.113012054564011
GO:0005172	vascular endothelial growth factor receptor binding	5/2227	13/18639	0.384615384615385	3.21905979068081	0.0136480317773259	0.113012054564011
GO:0019855	calcium channel inhibitor activity	5/2227	13/18639	0.384615384615385	3.21905979068081	0.0136480317773259	0.113012054564011
GO:0043560	insulin receptor substrate binding	5/2227	13/18639	0.384615384615385	3.21905979068081	0.0136480317773259	0.113012054564011
GO:0140852	histone ubiquitin ligase activity	5/2227	13/18639	0.384615384615385	3.21905979068081	0.0136480317773259	0.113012054564011
GO:0015101	organic cation transmembrane transporter activity	17/2227	81/18639	0.209876543209877	1.75657336726039	0.0140193812703029	0.113012054564011
GO:0033192	calmodulin-dependent protein phosphatase activity	17/2227	81/18639	0.209876543209877	1.75657336726039	0.0140193812703029	0.113012054564011
GO:0140791	histone H2AXS140 phosphatase activity	17/2227	81/18639	0.209876543209877	1.75657336726039	0.0140193812703029	0.113012054564011
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	17/2227	81/18639	0.209876543209877	1.75657336726039	0.0140193812703029	0.113012054564011
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	17/2227	81/18639	0.209876543209877	1.75657336726039	0.0140193812703029	0.113012054564011
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	17/2227	81/18639	0.209876543209877	1.75657336726039	0.0140193812703029	0.113012054564011
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	17/2227	81/18639	0.209876543209877	1.75657336726039	0.0140193812703029	0.113012054564011
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	17/2227	81/18639	0.209876543209877	1.75657336726039	0.0140193812703029	0.113012054564011
GO:1990439	MAP kinase serine/threonine phosphatase activity	17/2227	81/18639	0.209876543209877	1.75657336726039	0.0140193812703029	0.113012054564011
GO:0016741	transferase activity, transferring one-carbon groups	37/2227	215/18639	0.172093023255814	1.44034210169067	0.0141058782089318	0.113012054564011
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	10/2227	39/18639	0.256410256410256	2.14603986045387	0.0141486140299231	0.113012054564011
GO:0042171	lysophosphatidic acid acyltransferase activity	7/2227	23/18639	0.304347826086957	2.54725600827785	0.0149234660378933	0.115549903214372
GO:0071617	lysophospholipid acyltransferase activity	7/2227	23/18639	0.304347826086957	2.54725600827785	0.0149234660378933	0.115549903214372
GO:0140102	catalytic activity, acting on a rRNA	7/2227	23/18639	0.304347826086957	2.54725600827785	0.0149234660378933	0.115549903214372
GO:0140103	catalytic activity, acting on a glycoprotein	7/2227	23/18639	0.304347826086957	2.54725600827785	0.0149234660378933	0.115549903214372
GO:0003746	translation elongation factor activity	6/2227	18/18639	0.333333333333333	2.78985181859003	0.0150088293690029	0.115549903214372
GO:0070628	proteasome binding	6/2227	18/18639	0.333333333333333	2.78985181859003	0.0150088293690029	0.115549903214372
GO:0016504	peptidase activator activity	13/2227	57/18639	0.228070175438596	1.90884598114055	0.0152481050733993	0.116689091519786
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	17/2227	82/18639	0.207317073170732	1.73515174083039	0.0157738407040047	0.119283836803065
GO:0033549	MAP kinase phosphatase activity	17/2227	82/18639	0.207317073170732	1.73515174083039	0.0157738407040047	0.119283836803065
GO:0004540	RNA nuclease activity	23/2227	121/18639	0.190082644628099	1.59090723539432	0.015888079914621	0.119440977240503
GO:0071949	FAD binding	10/2227	40/18639	0.25	2.09238886394252	0.0168976863903484	0.126287971969972
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	8/2227	29/18639	0.275862068965517	2.30884288435037	0.0175061253776273	0.129322706546866
GO:0097472	cyclin-dependent protein kinase activity	8/2227	29/18639	0.275862068965517	2.30884288435037	0.0175061253776273	0.129322706546866
GO:0140789	histone phosphatase activity	25/2227	136/18639	0.183823529411765	1.53852122348715	0.0183849371633089	0.134542837875646
GO:0003724	RNA helicase activity	16/2227	77/18639	0.207792207792208	1.73912840639379	0.0184233150455697	0.134542837875646
GO:0008017	microtubule binding	45/2227	276/18639	0.16304347826087	1.36460143300599	0.0186276738384874	0.135262313440835
GO:0019210	kinase inhibitor activity	18/2227	90/18639	0.2	1.67391109115402	0.0188735771796277	0.136273625059685
GO:0044548	S100 protein binding	5/2227	14/18639	0.357142857142857	2.98912694848932	0.0191772124500479	0.136918868777437
GO:0070742	C2H2 zinc finger domain binding	5/2227	14/18639	0.357142857142857	2.98912694848932	0.0191772124500479	0.136918868777437
GO:0017018	myosin phosphatase activity	17/2227	84/18639	0.202380952380952	1.69383860414395	0.0197894616694957	0.14050517785342
GO:0043495	protein-membrane adaptor activity	11/2227	47/18639	0.234042553191489	1.95883212794619	0.0204001502913349	0.144040840178597
GO:0004725	protein tyrosine phosphatase activity	19/2227	98/18639	0.193877551020408	1.6226689148942	0.0220135251282833	0.154578489637066
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	13/2227	60/18639	0.216666666666667	1.81340368208352	0.0229817729107568	0.154652760944703
GO:0008186	ATP-dependent activity, acting on RNA	16/2227	79/18639	0.20253164556962	1.69509983914331	0.0231534854067989	0.154652760944703
GO:0015485	cholesterol binding	12/2227	54/18639	0.222222222222222	1.85990121239335	0.0234672996948158	0.154652760944703
GO:0016859	cis-trans isomerase activity	10/2227	42/18639	0.238095238095238	1.99275129899288	0.0235479504069007	0.154652760944703
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	4/2227	10/18639	0.4	3.34782218230804	0.0235559119368774	0.154652760944703
GO:0005522	profilin binding	4/2227	10/18639	0.4	3.34782218230804	0.0235559119368774	0.154652760944703
GO:0005528	FK506 binding	4/2227	10/18639	0.4	3.34782218230804	0.0235559119368774	0.154652760944703
GO:0015658	branched-chain amino acid transmembrane transporter activity	4/2227	10/18639	0.4	3.34782218230804	0.0235559119368774	0.154652760944703
GO:0031996	thioesterase binding	4/2227	10/18639	0.4	3.34782218230804	0.0235559119368774	0.154652760944703
GO:0047429	nucleoside triphosphate diphosphatase activity	4/2227	10/18639	0.4	3.34782218230804	0.0235559119368774	0.154652760944703
GO:0098505	G-rich strand telomeric DNA binding	4/2227	10/18639	0.4	3.34782218230804	0.0235559119368774	0.154652760944703
GO:1905394	retromer complex binding	4/2227	10/18639	0.4	3.34782218230804	0.0235559119368774	0.154652760944703
GO:0120020	cholesterol transfer activity	7/2227	25/18639	0.28	2.34347552761563	0.0236691962492479	0.154652760944703
GO:0016791	phosphatase activity	44/2227	273/18639	0.161172161172161	1.34893934085672	0.0237182638068559	0.154652760944703
GO:0004713	protein tyrosine kinase activity	25/2227	140/18639	0.178571428571429	1.49456347424466	0.0255934726148024	0.163650519272274
GO:0048306	calcium-dependent protein binding	16/2227	80/18639	0.2	1.67391109115402	0.0258365679580284	0.163650519272274
GO:0030695	GTPase regulator activity	73/2227	489/18639	0.149284253578732	1.24944283900044	0.0259614289452257	0.163650519272274
GO:0000774	adenyl-nucleotide exchange factor activity	5/2227	15/18639	0.333333333333333	2.78985181859003	0.0259945660502908	0.163650519272274
GO:0005523	tropomyosin binding	5/2227	15/18639	0.333333333333333	2.78985181859003	0.0259945660502908	0.163650519272274
GO:0031386	protein tag activity	5/2227	15/18639	0.333333333333333	2.78985181859003	0.0259945660502908	0.163650519272274
GO:0141047	molecular tag activity	5/2227	15/18639	0.333333333333333	2.78985181859003	0.0259945660502908	0.163650519272274
GO:0140313	molecular sequestering activity	12/2227	55/18639	0.218181818181818	1.82608482671348	0.0268571883821935	0.168252386041389
GO:0060589	nucleoside-triphosphatase regulator activity	73/2227	490/18639	0.148979591836735	1.24689295565554	0.0270472350096314	0.168616421181995
GO:0001222	transcription corepressor binding	11/2227	49/18639	0.224489795918367	1.87887979619329	0.0273587541400933	0.169730523257472
GO:0019902	phosphatase binding	32/2227	190/18639	0.168421052631579	1.40960933991917	0.0280594207984055	0.173236424059721
GO:0035091	phosphatidylinositol binding	45/2227	284/18639	0.158450704225352	1.32616195601991	0.0291440825649639	0.179067968836653
GO:0016887	ATP hydrolysis activity	63/2227	417/18639	0.151079136690647	1.26446521274224	0.0293307642321007	0.179352711428827
GO:0070717	poly-purine tract binding	8/2227	32/18639	0.25	2.09238886394252	0.031091729617635	0.189201711328557
GO:0019787	ubiquitin-like protein transferase activity	71/2227	479/18639	0.148225469728601	1.2405812888511	0.0318682957001948	0.189201711328557
GO:0043531	ADP binding	9/2227	38/18639	0.236842105263158	1.98226313426134	0.0318821043205209	0.189201711328557
GO:0001046	core promoter sequence-specific DNA binding	10/2227	44/18639	0.227272727272727	1.9021716944932	0.0319033366019005	0.189201711328557
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	6/2227	21/18639	0.285714285714286	2.39130155879146	0.0321257991848958	0.189201711328557
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	6/2227	21/18639	0.285714285714286	2.39130155879146	0.0321257991848958	0.189201711328557
GO:0070182	DNA polymerase binding	6/2227	21/18639	0.285714285714286	2.39130155879146	0.0321257991848958	0.189201711328557
GO:0072542	protein phosphatase activator activity	6/2227	21/18639	0.285714285714286	2.39130155879146	0.0321257991848958	0.189201711328557
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	4/2227	11/18639	0.363636363636364	3.04347471118913	0.0335812556233297	0.195967327336143
GO:0045294	alpha-catenin binding	4/2227	11/18639	0.363636363636364	3.04347471118913	0.0335812556233297	0.195967327336143
GO:0005159	insulin-like growth factor receptor binding	5/2227	16/18639	0.3125	2.61548607992815	0.034181819575887	0.19766681184608
GO:0055102	lipase inhibitor activity	5/2227	16/18639	0.3125	2.61548607992815	0.034181819575887	0.19766681184608
GO:0016755	aminoacyltransferase activity	73/2227	496/18639	0.147177419354839	1.23180957312745	0.034344471446171	0.197712768054985
GO:0016922	nuclear receptor binding	24/2227	137/18639	0.175182481751825	1.46619949590133	0.0346453685815025	0.198550587655427
GO:0008266	poly(U) RNA binding	7/2227	27/18639	0.259259259259259	2.16988474779225	0.0354102638057125	0.201130298416447
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	7/2227	27/18639	0.259259259259259	2.16988474779225	0.0354102638057125	0.201130298416447
GO:0004518	nuclease activity	34/2227	209/18639	0.162679425837321	1.36155447605829	0.0378446879133256	0.214006686518717
GO:0008649	rRNA methyltransferase activity	6/2227	22/18639	0.272727272727273	2.28260603339184	0.0398424973784882	0.222517277161049
GO:0061133	endopeptidase activator activity	6/2227	22/18639	0.272727272727273	2.28260603339184	0.0398424973784882	0.222517277161049
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	28/2227	167/18639	0.167664670658683	1.40327875905127	0.0398720316665729	0.222517277161049
GO:0030331	nuclear estrogen receptor binding	9/2227	40/18639	0.225	1.88314997754827	0.0430969960901571	0.237522694564005
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	9/2227	40/18639	0.225	1.88314997754827	0.0430969960901571	0.237522694564005
GO:0008168	methyltransferase activity	33/2227	204/18639	0.161764705882353	1.35389867666869	0.0431183608285205	0.237522694564005
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	8/2227	34/18639	0.235294117647059	1.96930716606355	0.0433589621610478	0.237526523836775
GO:0004659	prenyltransferase activity	5/2227	17/18639	0.294117647058824	2.46163395757944	0.0437956766396113	0.237526523836775
GO:0045236	CXCR chemokine receptor binding	5/2227	17/18639	0.294117647058824	2.46163395757944	0.0437956766396113	0.237526523836775
GO:0001786	phosphatidylserine binding	12/2227	59/18639	0.203389830508475	1.70228246558036	0.0439988356496063	0.237526523836775
GO:0004859	phospholipase inhibitor activity	4/2227	12/18639	0.333333333333333	2.78985181859003	0.045721067968581	0.237526523836775
GO:0005527	macrolide binding	4/2227	12/18639	0.333333333333333	2.78985181859003	0.045721067968581	0.237526523836775
GO:0008179	adenylate cyclase binding	4/2227	12/18639	0.333333333333333	2.78985181859003	0.045721067968581	0.237526523836775
GO:0016273	arginine N-methyltransferase activity	4/2227	12/18639	0.333333333333333	2.78985181859003	0.045721067968581	0.237526523836775
GO:0016274	protein-arginine N-methyltransferase activity	4/2227	12/18639	0.333333333333333	2.78985181859003	0.045721067968581	0.237526523836775
GO:0017166	vinculin binding	4/2227	12/18639	0.333333333333333	2.78985181859003	0.045721067968581	0.237526523836775
GO:0035197	siRNA binding	4/2227	12/18639	0.333333333333333	2.78985181859003	0.045721067968581	0.237526523836775
GO:0043047	single-stranded telomeric DNA binding	4/2227	12/18639	0.333333333333333	2.78985181859003	0.045721067968581	0.237526523836775
GO:0097677	STAT family protein binding	4/2227	12/18639	0.333333333333333	2.78985181859003	0.045721067968581	0.237526523836775
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/2227	12/18639	0.333333333333333	2.78985181859003	0.045721067968581	0.237526523836775
GO:0140296	general transcription initiation factor binding	11/2227	53/18639	0.207547169811321	1.73707754742398	0.0461060757173564	0.238556942375633
GO:0016209	antioxidant activity	16/2227	86/18639	0.186046511627907	1.55712659642234	0.047013939435474	0.242273445961838
GO:0019888	protein phosphatase regulator activity	19/2227	107/18639	0.177570093457944	1.48618274448254	0.049382186986074	0.253455562121295
GO:0000175	3'-5'-RNA exonuclease activity	8/2227	35/18639	0.228571428571429	1.91304124703316	0.0505401289308201	0.258361139094352
GO:0035401	histone H3Y41 kinase activity	20/2227	115/18639	0.173913043478261	1.45557486187306	0.0537264137600538	0.27246966978313
GO:0140801	histone H2AXY142 kinase activity	20/2227	115/18639	0.173913043478261	1.45557486187306	0.0537264137600538	0.27246966978313
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	5/2227	18/18639	0.277777777777778	2.32487651549169	0.0548675409744608	0.277156985633838
GO:0001618	virus receptor activity	15/2227	81/18639	0.185185185185185	1.54991767699446	0.0551278409591852	0.277375514747397
GO:0061659	ubiquitin-like protein ligase activity	55/2227	372/18639	0.147849462365591	1.23743427437461	0.0553749525474776	0.277526232767358
GO:0031492	nucleosomal DNA binding	9/2227	42/18639	0.214285714285714	1.79347616909359	0.0566883352628247	0.282499607541476
GO:0019903	protein phosphatase binding	24/2227	144/18639	0.166666666666667	1.39492590929502	0.0570424504852613	0.282499607541476
GO:0032934	sterol binding	13/2227	68/18639	0.191176470588235	1.60006207242664	0.0572514854094228	0.282499607541476
GO:1990841	promoter-specific chromatin binding	13/2227	68/18639	0.191176470588235	1.60006207242664	0.0572514854094228	0.282499607541476
GO:0008238	exopeptidase activity	18/2227	102/18639	0.176470588235294	1.47698037454766	0.0575173322371349	0.282719809996378
GO:0004842	ubiquitin-protein transferase activity	65/2227	449/18639	0.144766146993318	1.21162829537874	0.0577717851504097	0.282882534184765
GO:0005035	death receptor activity	4/2227	13/18639	0.307692307692308	2.57524783254464	0.05997575072025	0.289241544982941
GO:0019104	DNA N-glycosylase activity	4/2227	13/18639	0.307692307692308	2.57524783254464	0.05997575072025	0.289241544982941
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	4/2227	13/18639	0.307692307692308	2.57524783254464	0.05997575072025	0.289241544982941
GO:0140666	annealing activity	4/2227	13/18639	0.307692307692308	2.57524783254464	0.05997575072025	0.289241544982941
GO:0140272	exogenous protein binding	15/2227	82/18639	0.182926829268293	1.53101624190916	0.060330334221709	0.289857771185504
GO:0015179	L-amino acid transmembrane transporter activity	12/2227	62/18639	0.193548387096774	1.61991395918131	0.0610090255708691	0.291050340030501
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	16/2227	89/18639	0.179775280898876	1.50463918305979	0.0612617695369365	0.291050340030501
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	16/2227	89/18639	0.179775280898876	1.50463918305979	0.0612617695369365	0.291050340030501
GO:0019208	phosphatase regulator activity	20/2227	117/18639	0.170940170940171	1.43069324030258	0.0623503331183781	0.295124910093656
GO:0061630	ubiquitin protein ligase activity	52/2227	353/18639	0.147308781869688	1.2329090189803	0.0642696870470137	0.301544941097921
GO:0004712	protein serine/threonine/tyrosine kinase activity	9/2227	43/18639	0.209302325581395	1.75176742097514	0.0644145296711521	0.301544941097921
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	9/2227	43/18639	0.209302325581395	1.75176742097514	0.0644145296711521	0.301544941097921
GO:0061134	peptidase regulator activity	35/2227	226/18639	0.154867256637168	1.29617009270776	0.064692277353946	0.301739892183734
GO:0140793	histone H2AXY142 phosphatase activity	16/2227	90/18639	0.177777777777778	1.48792096991468	0.0666014358636692	0.309515036486434
GO:0016411	acylglycerol O-acyltransferase activity	7/2227	31/18639	0.225806451612903	1.88989961904486	0.0690199938631663	0.31843881645172
GO:0140457	protein demethylase activity	7/2227	31/18639	0.225806451612903	1.88989961904486	0.0690199938631663	0.31843881645172
GO:0019211	phosphatase activator activity	6/2227	25/18639	0.24	2.00869330938482	0.0695448383778442	0.31970612750678
GO:0004601	peroxidase activity	11/2227	57/18639	0.192982456140351	1.61517736865739	0.0721217696805388	0.328597538078608
GO:0072341	modified amino acid binding	16/2227	91/18639	0.175824175824176	1.47157019002551	0.0722452636783973	0.328597538078608
GO:0008237	metallopeptidase activity	29/2227	184/18639	0.157608695652174	1.31911471857246	0.0722503194053904	0.328597538078608
GO:0004386	helicase activity	25/2227	155/18639	0.161290322580645	1.34992829931776	0.072690749922517	0.329428292202045
GO:0005545	1-phosphatidylinositol binding	4/2227	14/18639	0.285714285714286	2.39130155879146	0.0762951660283308	0.341744155032328
GO:0034236	protein kinase A catalytic subunit binding	4/2227	14/18639	0.285714285714286	2.39130155879146	0.0762951660283308	0.341744155032328
GO:0042826	histone deacetylase binding	21/2227	127/18639	0.165354330708661	1.38394224071789	0.0763142384743131	0.341744155032328
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	8/2227	38/18639	0.210526315789474	1.76201167489897	0.0764779564469841	0.341744155032328
GO:0120015	sterol transfer activity	7/2227	32/18639	0.21875	1.83084025594971	0.079639907851915	0.354633457263928
GO:0030742	GTP-dependent protein binding	5/2227	20/18639	0.25	2.09238886394252	0.0813888353062122	0.358389220310119
GO:0070006	metalloaminopeptidase activity	6/2227	26/18639	0.230769230769231	1.93143587440848	0.0816653831518973	0.358389220310119
GO:0004715	non-membrane spanning protein tyrosine kinase activity	9/2227	45/18639	0.2	1.67391109115402	0.0817735810504801	0.358389220310119
GO:0046915	transition metal ion transmembrane transporter activity	9/2227	45/18639	0.2	1.67391109115402	0.0817735810504801	0.358389220310119
GO:0120013	lipid transfer activity	12/2227	65/18639	0.184615384615385	1.54514869952679	0.0818854869566156	0.358389220310119
GO:0002020	protease binding	22/2227	136/18639	0.161764705882353	1.35389867666869	0.0856850281309995	0.373738791643062
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	11/2227	59/18639	0.186440677966102	1.56042559344866	0.0880531029880345	0.382761447682681
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	7/2227	33/18639	0.212121212121212	1.77536024819366	0.0911511111977941	0.394885152917901
GO:0042578	phosphoric ester hydrolase activity	52/2227	363/18639	0.143250688705234	1.19894458319572	0.0942547748874837	0.406224376594169
GO:0140104	molecular carrier activity	37/2227	249/18639	0.14859437751004	1.24366888298592	0.0947927424103628	0.406224376594169
GO:0005385	zinc ion transmembrane transporter activity	6/2227	27/18639	0.222222222222222	1.85990121239335	0.0948811315365217	0.406224376594169
GO:0009055	electron transfer activity	19/2227	116/18639	0.163793103448276	1.37087546258303	0.0950399754316562	0.406224376594169
GO:0035613	RNA stem-loop binding	5/2227	21/18639	0.238095238095238	1.99275129899288	0.0967835340941237	0.412297855240967
GO:0004532	RNA exonuclease activity	8/2227	40/18639	0.2	1.67391109115402	0.0974928110649924	0.413939576548373
GO:0003735	structural constituent of ribosome	27/2227	175/18639	0.154285714285714	1.29130284174739	0.0981750664698922	0.415456075988484
GO:0031491	nucleosome binding	13/2227	74/18639	0.175675675675676	1.47032730979745	0.0986348779100314	0.41602433653142
GO:0030332	cyclin binding	7/2227	34/18639	0.205882352941176	1.72314377030561	0.103541668355469	0.425344040121195
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	10/2227	54/18639	0.185185185185185	1.54991767699446	0.104375080705102	0.425344040121195
GO:0051287	NAD binding	10/2227	54/18639	0.185185185185185	1.54991767699446	0.104375080705102	0.425344040121195
GO:0061135	endopeptidase regulator activity	28/2227	184/18639	0.152173913043478	1.27362800413893	0.106344875538186	0.425344040121195
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	34/2227	229/18639	0.148471615720524	1.24264142138071	0.106363677495559	0.425344040121195
GO:0001094	TFIID-class transcription factor complex binding	3/2227	10/18639	0.3	2.51086663673103	0.107531688706176	0.425344040121195
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	3/2227	10/18639	0.3	2.51086663673103	0.107531688706176	0.425344040121195
GO:0005031	tumor necrosis factor receptor activity	3/2227	10/18639	0.3	2.51086663673103	0.107531688706176	0.425344040121195
GO:0005131	growth hormone receptor binding	3/2227	10/18639	0.3	2.51086663673103	0.107531688706176	0.425344040121195
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	3/2227	10/18639	0.3	2.51086663673103	0.107531688706176	0.425344040121195
GO:0016868	intramolecular phosphotransferase activity	3/2227	10/18639	0.3	2.51086663673103	0.107531688706176	0.425344040121195
GO:0030957	Tat protein binding	3/2227	10/18639	0.3	2.51086663673103	0.107531688706176	0.425344040121195
GO:0031720	haptoglobin binding	3/2227	10/18639	0.3	2.51086663673103	0.107531688706176	0.425344040121195
GO:0033204	ribonuclease P RNA binding	3/2227	10/18639	0.3	2.51086663673103	0.107531688706176	0.425344040121195
GO:0051880	G-quadruplex DNA binding	3/2227	10/18639	0.3	2.51086663673103	0.107531688706176	0.425344040121195
GO:0140940	histone H2A methyltransferase activity	3/2227	10/18639	0.3	2.51086663673103	0.107531688706176	0.425344040121195
GO:1990259	histone H2AQ104 methyltransferase activity	3/2227	10/18639	0.3	2.51086663673103	0.107531688706176	0.425344040121195
GO:1990763	arrestin family protein binding	3/2227	10/18639	0.3	2.51086663673103	0.107531688706176	0.425344040121195
GO:0015175	neutral L-amino acid transmembrane transporter activity	8/2227	41/18639	0.195121951219512	1.63308399136977	0.109106383632925	0.425344040121195
GO:0016877	ligase activity, forming carbon-sulfur bonds	8/2227	41/18639	0.195121951219512	1.63308399136977	0.109106383632925	0.425344040121195
GO:0042169	SH2 domain binding	8/2227	41/18639	0.195121951219512	1.63308399136977	0.109106383632925	0.425344040121195
GO:0042287	MHC protein binding	8/2227	41/18639	0.195121951219512	1.63308399136977	0.109106383632925	0.425344040121195
GO:0051119	sugar transmembrane transporter activity	6/2227	28/18639	0.214285714285714	1.79347616909359	0.109164980563186	0.425344040121195
GO:0051959	dynein light intermediate chain binding	6/2227	28/18639	0.214285714285714	1.79347616909359	0.109164980563186	0.425344040121195
GO:0141052	histone H3 demethylase activity	6/2227	28/18639	0.214285714285714	1.79347616909359	0.109164980563186	0.425344040121195
GO:1902936	phosphatidylinositol bisphosphate binding	18/2227	111/18639	0.162162162162162	1.3572252090438	0.109654771533103	0.425953793371751
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	9/2227	48/18639	0.1875	1.56929164795689	0.11259645356431	0.435055159145603
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	5/2227	22/18639	0.227272727272727	1.9021716944932	0.113530897834016	0.435055159145603
GO:0050321	tau-protein kinase activity	5/2227	22/18639	0.227272727272727	1.9021716944932	0.113530897834016	0.435055159145603
GO:0008374	O-acyltransferase activity	10/2227	55/18639	0.181818181818182	1.52173735559456	0.114645667295852	0.435055159145603
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	4/2227	16/18639	0.25	2.09238886394252	0.114721117865468	0.435055159145603
GO:0004708	MAP kinase kinase activity	4/2227	16/18639	0.25	2.09238886394252	0.114721117865468	0.435055159145603
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/2227	16/18639	0.25	2.09238886394252	0.114721117865468	0.435055159145603
GO:0043023	ribosomal large subunit binding	4/2227	16/18639	0.25	2.09238886394252	0.114721117865468	0.435055159145603
GO:0005154	epidermal growth factor receptor binding	7/2227	35/18639	0.2	1.67391109115402	0.116792053211631	0.440382595528714
GO:0005200	structural constituent of cytoskeleton	18/2227	112/18639	0.160714285714286	1.34510712682019	0.116815101630856	0.440382595528714
GO:0008307	structural constituent of muscle	8/2227	42/18639	0.19047619047619	1.5942010391943	0.121440042072949	0.455133060906828
GO:0048487	beta-tubulin binding	8/2227	42/18639	0.19047619047619	1.5942010391943	0.121440042072949	0.455133060906828
GO:0003785	actin monomer binding	6/2227	29/18639	0.206896551724138	1.73163216326278	0.124478841219032	0.465157775081647
GO:0097110	scaffold protein binding	12/2227	70/18639	0.171428571428571	1.43478093527487	0.125553625250004	0.467806218861531
GO:0140597	protein carrier chaperone	28/2227	188/18639	0.148936170212766	1.24652953596576	0.128776585440158	0.47841998893175
GO:0005484	SNAP receptor activity	7/2227	36/18639	0.194444444444444	1.62741356084419	0.130875603452806	0.483389624496797
GO:0055106	ubiquitin-protein transferase regulator activity	7/2227	36/18639	0.194444444444444	1.62741356084419	0.130875603452806	0.483389624496797
GO:0004602	glutathione peroxidase activity	5/2227	23/18639	0.217391304347826	1.81946857734132	0.131556855672259	0.483389624496797
GO:0035591	signaling adaptor activity	20/2227	129/18639	0.155038759689922	1.29760549701862	0.133978087592054	0.483389624496797
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/2227	11/18639	0.272727272727273	2.28260603339184	0.135263101112243	0.483389624496797
GO:0004523	RNA-DNA hybrid ribonuclease activity	3/2227	11/18639	0.272727272727273	2.28260603339184	0.135263101112243	0.483389624496797
GO:0005225	volume-sensitive anion channel activity	3/2227	11/18639	0.272727272727273	2.28260603339184	0.135263101112243	0.483389624496797
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/2227	11/18639	0.272727272727273	2.28260603339184	0.135263101112243	0.483389624496797
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	3/2227	11/18639	0.272727272727273	2.28260603339184	0.135263101112243	0.483389624496797
GO:0042608	T cell receptor binding	3/2227	11/18639	0.272727272727273	2.28260603339184	0.135263101112243	0.483389624496797
GO:0048185	activin binding	3/2227	11/18639	0.272727272727273	2.28260603339184	0.135263101112243	0.483389624496797
GO:0070990	snRNP binding	3/2227	11/18639	0.272727272727273	2.28260603339184	0.135263101112243	0.483389624496797
GO:0140031	phosphorylation-dependent protein binding	3/2227	11/18639	0.272727272727273	2.28260603339184	0.135263101112243	0.483389624496797
GO:0004549	tRNA-specific ribonuclease activity	4/2227	17/18639	0.235294117647059	1.96930716606355	0.136544330550347	0.483389624496797
GO:0032183	SUMO binding	4/2227	17/18639	0.235294117647059	1.96930716606355	0.136544330550347	0.483389624496797
GO:0038191	neuropilin binding	4/2227	17/18639	0.235294117647059	1.96930716606355	0.136544330550347	0.483389624496797
GO:0048038	quinone binding	4/2227	17/18639	0.235294117647059	1.96930716606355	0.136544330550347	0.483389624496797
GO:0051213	dioxygenase activity	15/2227	93/18639	0.161290322580645	1.34992829931776	0.139614262220944	0.492892340105984
GO:0001968	fibronectin binding	6/2227	30/18639	0.2	1.67391109115402	0.140774710389664	0.494258461203272
GO:0032452	histone demethylase activity	6/2227	30/18639	0.2	1.67391109115402	0.140774710389664	0.494258461203272
GO:0043394	proteoglycan binding	7/2227	37/18639	0.189189189189189	1.5834294105511	0.145759061191956	0.509385539285202
GO:0003774	cytoskeletal motor activity	23/2227	153/18639	0.150326797385621	1.25816846720727	0.145880365710785	0.509385539285202
GO:0008408	3'-5' exonuclease activity	10/2227	58/18639	0.172413793103448	1.44302680271898	0.14867819826862	0.517367995083571
GO:0030544	Hsp70 protein binding	9/2227	51/18639	0.176470588235294	1.47698037454766	0.148976073701686	0.517367995083571
GO:0046982	protein heterodimerization activity	51/2227	369/18639	0.138211382113821	1.15676782722026	0.149518579126009	0.517844835021789
GO:0001091	RNA polymerase II general transcription initiation factor binding	5/2227	24/18639	0.208333333333333	1.74365738661877	0.150773216568384	0.51797895369461
GO:0015149	hexose transmembrane transporter activity	5/2227	24/18639	0.208333333333333	1.74365738661877	0.150773216568384	0.51797895369461
GO:0055056	D-glucose transmembrane transporter activity	5/2227	24/18639	0.208333333333333	1.74365738661877	0.150773216568384	0.51797895369461
GO:0043539	protein serine/threonine kinase activator activity	12/2227	73/18639	0.164383561643836	1.37581733519508	0.156963518494621	0.535561292742757
GO:0005164	tumor necrosis factor receptor binding	6/2227	31/18639	0.193548387096774	1.61991395918131	0.157995842356024	0.535561292742757
GO:1901981	phosphatidylinositol phosphate binding	27/2227	185/18639	0.145945945945946	1.22150268813942	0.158037274917584	0.535561292742757
GO:0005543	phospholipid binding	67/2227	497/18639	0.134808853118712	1.12829017210583	0.159071997622262	0.535561292742757
GO:0008235	metalloexopeptidase activity	11/2227	66/18639	0.166666666666667	1.39492590929502	0.159217446944012	0.535561292742757
GO:0017128	phospholipid scramblase activity	4/2227	18/18639	0.222222222222222	1.85990121239335	0.159880556143457	0.535561292742757
GO:0031690	adrenergic receptor binding	4/2227	18/18639	0.222222222222222	1.85990121239335	0.159880556143457	0.535561292742757
GO:1901611	phosphatidylglycerol binding	4/2227	18/18639	0.222222222222222	1.85990121239335	0.159880556143457	0.535561292742757
GO:0004197	cysteine-type endopeptidase activity	14/2227	88/18639	0.159090909090909	1.33152018614524	0.161758119309288	0.535561292742757
GO:0000340	RNA 7-methylguanosine cap binding	3/2227	12/18639	0.25	2.09238886394252	0.165110445493463	0.535561292742757
GO:0003720	telomerase activity	3/2227	12/18639	0.25	2.09238886394252	0.165110445493463	0.535561292742757
GO:0003995	acyl-CoA dehydrogenase activity	3/2227	12/18639	0.25	2.09238886394252	0.165110445493463	0.535561292742757
GO:0004526	ribonuclease P activity	3/2227	12/18639	0.25	2.09238886394252	0.165110445493463	0.535561292742757
GO:0016208	AMP binding	3/2227	12/18639	0.25	2.09238886394252	0.165110445493463	0.535561292742757
GO:0016423	tRNA (guanine) methyltransferase activity	3/2227	12/18639	0.25	2.09238886394252	0.165110445493463	0.535561292742757
GO:0016801	hydrolase activity, acting on ether bonds	3/2227	12/18639	0.25	2.09238886394252	0.165110445493463	0.535561292742757
GO:0016803	ether hydrolase activity	3/2227	12/18639	0.25	2.09238886394252	0.165110445493463	0.535561292742757
GO:0035259	nuclear glucocorticoid receptor binding	3/2227	12/18639	0.25	2.09238886394252	0.165110445493463	0.535561292742757
GO:0036009	protein-glutamine N-methyltransferase activity	3/2227	12/18639	0.25	2.09238886394252	0.165110445493463	0.535561292742757
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	3/2227	12/18639	0.25	2.09238886394252	0.165110445493463	0.535561292742757
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/2227	12/18639	0.25	2.09238886394252	0.165110445493463	0.535561292742757
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	3/2227	12/18639	0.25	2.09238886394252	0.165110445493463	0.535561292742757
GO:0017025	TBP-class protein binding	5/2227	25/18639	0.2	1.67391109115402	0.171080311116019	0.551793300530407
GO:0017056	structural constituent of nuclear pore	5/2227	25/18639	0.2	1.67391109115402	0.171080311116019	0.551793300530407
GO:0140713	histone chaperone activity	24/2227	164/18639	0.146341463414634	1.22481299352733	0.171409968944109	0.551793300530407
GO:0008378	galactosyltransferase activity	6/2227	32/18639	0.1875	1.56929164795689	0.176077981087741	0.558422290913709
GO:0043425	bHLH transcription factor binding	6/2227	32/18639	0.1875	1.56929164795689	0.176077981087741	0.558422290913709
GO:0005544	calcium-dependent phospholipid binding	9/2227	53/18639	0.169811320754717	1.42124526607417	0.176090910202054	0.558422290913709
GO:0016860	intramolecular oxidoreductase activity	9/2227	53/18639	0.169811320754717	1.42124526607417	0.176090910202054	0.558422290913709
GO:0051018	protein kinase A binding	9/2227	53/18639	0.169811320754717	1.42124526607417	0.176090910202054	0.558422290913709
GO:1901505	carbohydrate derivative transmembrane transporter activity	9/2227	53/18639	0.169811320754717	1.42124526607417	0.176090910202054	0.558422290913709
GO:0030291	protein serine/threonine kinase inhibitor activity	8/2227	46/18639	0.173913043478261	1.45557486187306	0.177520048270076	0.561560944775142
GO:0140658	ATP-dependent chromatin remodeler activity	23/2227	158/18639	0.145569620253165	1.21835300938425	0.184258285492313	0.576634021505398
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	26/2227	181/18639	0.143646408839779	1.20225658480675	0.184417982175213	0.576634021505398
GO:0008301	DNA binding, bending	4/2227	19/18639	0.210526315789474	1.76201167489897	0.18454093489492	0.576634021505398
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	4/2227	19/18639	0.210526315789474	1.76201167489897	0.18454093489492	0.576634021505398
GO:0043395	heparan sulfate proteoglycan binding	4/2227	19/18639	0.210526315789474	1.76201167489897	0.18454093489492	0.576634021505398
GO:0000510	H3-H4 histone complex chaperone activity	22/2227	151/18639	0.145695364238411	1.219405430642	0.189550929469123	0.580415222440406
GO:0140584	chromatin extrusion motor activity	22/2227	151/18639	0.145695364238411	1.219405430642	0.189550929469123	0.580415222440406
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	22/2227	151/18639	0.145695364238411	1.219405430642	0.189550929469123	0.580415222440406
GO:0140849	ATP-dependent H2AZ histone chaperone activity	22/2227	151/18639	0.145695364238411	1.219405430642	0.189550929469123	0.580415222440406
GO:0016779	nucleotidyltransferase activity	20/2227	136/18639	0.147058823529412	1.23081697878972	0.191660051976052	0.580415222440406
GO:0019838	growth factor binding	20/2227	136/18639	0.147058823529412	1.23081697878972	0.191660051976052	0.580415222440406
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/2227	26/18639	0.192307692307692	1.6095298953404	0.192369579678905	0.580415222440406
GO:0008157	protein phosphatase 1 binding	5/2227	26/18639	0.192307692307692	1.6095298953404	0.192369579678905	0.580415222440406
GO:0015145	monosaccharide transmembrane transporter activity	5/2227	26/18639	0.192307692307692	1.6095298953404	0.192369579678905	0.580415222440406
GO:0034237	protein kinase A regulatory subunit binding	5/2227	26/18639	0.192307692307692	1.6095298953404	0.192369579678905	0.580415222440406
GO:0043548	phosphatidylinositol 3-kinase binding	5/2227	26/18639	0.192307692307692	1.6095298953404	0.192369579678905	0.580415222440406
GO:0000149	SNARE binding	16/2227	106/18639	0.150943396226415	1.26332912539926	0.194151619726059	0.580415222440406
GO:0015036	disulfide oxidoreductase activity	7/2227	40/18639	0.175	1.46467220475977	0.194790485024894	0.580415222440406
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	7/2227	40/18639	0.175	1.46467220475977	0.194790485024894	0.580415222440406
GO:0032451	demethylase activity	7/2227	40/18639	0.175	1.46467220475977	0.194790485024894	0.580415222440406
GO:0002039	p53 binding	11/2227	69/18639	0.159420289855072	1.33427695671697	0.196530323074475	0.580415222440406
GO:0003964	RNA-directed DNA polymerase activity	3/2227	13/18639	0.230769230769231	1.93143587440848	0.196650853925427	0.580415222440406
GO:0005338	nucleotide-sugar transmembrane transporter activity	3/2227	13/18639	0.230769230769231	1.93143587440848	0.196650853925427	0.580415222440406
GO:0005542	folic acid binding	3/2227	13/18639	0.230769230769231	1.93143587440848	0.196650853925427	0.580415222440406
GO:0008253	5'-nucleotidase activity	3/2227	13/18639	0.230769230769231	1.93143587440848	0.196650853925427	0.580415222440406
GO:0030955	potassium ion binding	3/2227	13/18639	0.230769230769231	1.93143587440848	0.196650853925427	0.580415222440406
GO:0035325	Toll-like receptor binding	3/2227	13/18639	0.230769230769231	1.93143587440848	0.196650853925427	0.580415222440406
GO:0035673	oligopeptide transmembrane transporter activity	3/2227	13/18639	0.230769230769231	1.93143587440848	0.196650853925427	0.580415222440406
GO:0061459	L-arginine transmembrane transporter activity	3/2227	13/18639	0.230769230769231	1.93143587440848	0.196650853925427	0.580415222440406
GO:0015616	DNA translocase activity	22/2227	152/18639	0.144736842105263	1.21138302649304	0.198139005608866	0.582118733719841
GO:0140674	ATP-dependent histone chaperone activity	22/2227	152/18639	0.144736842105263	1.21138302649304	0.198139005608866	0.582118733719841
GO:0003689	DNA clamp loader activity	23/2227	160/18639	0.14375	1.20312359676695	0.200944895553471	0.589008203021411
GO:0043178	alcohol binding	14/2227	92/18639	0.152173913043478	1.27362800413893	0.205272276227299	0.600315718577776
GO:0061775	cohesin loader activity	22/2227	153/18639	0.143790849673203	1.20346549037217	0.206915265744421	0.60373906306249
GO:0001221	transcription coregulator binding	17/2227	115/18639	0.147826086956522	1.2372386325921	0.209058444840599	0.606772935923929
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	4/2227	20/18639	0.2	1.67391109115402	0.210328959792097	0.606772935923929
GO:0015095	magnesium ion transmembrane transporter activity	4/2227	20/18639	0.2	1.67391109115402	0.210328959792097	0.606772935923929
GO:0061608	nuclear import signal receptor activity	4/2227	20/18639	0.2	1.67391109115402	0.210328959792097	0.606772935923929
GO:0140939	histone H4 methyltransferase activity	4/2227	20/18639	0.2	1.67391109115402	0.210328959792097	0.606772935923929
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	7/2227	41/18639	0.170731707317073	1.42894849244855	0.212431329429123	0.611457745518963
GO:0001671	ATPase activator activity	5/2227	27/18639	0.185185185185185	1.54991767699446	0.214526045165811	0.616099518476193
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	13/2227	86/18639	0.151162790697674	1.26516535959315	0.223428299629734	0.640227280104934
GO:0016763	pentosyltransferase activity	8/2227	49/18639	0.163265306122449	1.36645803359512	0.225765387221902	0.645476878902889
GO:0005344	oxygen carrier activity	3/2227	14/18639	0.214285714285714	1.79347616909359	0.229475132442817	0.648825706331682
GO:0008191	metalloendopeptidase inhibitor activity	3/2227	14/18639	0.214285714285714	1.79347616909359	0.229475132442817	0.648825706331682
GO:0032454	histone H3K9 demethylase activity	3/2227	14/18639	0.214285714285714	1.79347616909359	0.229475132442817	0.648825706331682
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	3/2227	14/18639	0.214285714285714	1.79347616909359	0.229475132442817	0.648825706331682
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	3/2227	14/18639	0.214285714285714	1.79347616909359	0.229475132442817	0.648825706331682
GO:0046332	SMAD binding	12/2227	79/18639	0.151898734177215	1.27132487935748	0.230220122245869	0.649495179316161
GO:0031406	carboxylic acid binding	26/2227	187/18639	0.13903743315508	1.16368150721937	0.232922126543327	0.655670655776149
GO:0015171	amino acid transmembrane transporter activity	15/2227	102/18639	0.147058823529412	1.23081697878972	0.23348249729866	0.655803585819094
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4/2227	21/18639	0.19047619047619	1.5942010391943	0.237045530544562	0.656788610428628
GO:0015174	basic amino acid transmembrane transporter activity	4/2227	21/18639	0.19047619047619	1.5942010391943	0.237045530544562	0.656788610428628
GO:1904047	S-adenosyl-L-methionine binding	4/2227	21/18639	0.19047619047619	1.5942010391943	0.237045530544562	0.656788610428628
GO:0019789	SUMO transferase activity	5/2227	28/18639	0.178571428571429	1.49456347424466	0.23743062442725	0.656788610428628
GO:0046625	sphingolipid binding	5/2227	28/18639	0.178571428571429	1.49456347424466	0.23743062442725	0.656788610428628
GO:0046875	ephrin receptor binding	5/2227	28/18639	0.178571428571429	1.49456347424466	0.23743062442725	0.656788610428628
GO:0051019	mitogen-activated protein kinase binding	5/2227	28/18639	0.178571428571429	1.49456347424466	0.23743062442725	0.656788610428628
GO:0032813	tumor necrosis factor receptor superfamily binding	8/2227	50/18639	0.16	1.33912887292322	0.242814800457462	0.670231781824268
GO:0005126	cytokine receptor binding	37/2227	275/18639	0.134545454545455	1.12608564313998	0.243637571801872	0.67105348440257
GO:0008375	acetylglucosaminyltransferase activity	7/2227	43/18639	0.162790697674419	1.36248577186955	0.249326420065607	0.685245515793218
GO:0043177	organic acid binding	26/2227	189/18639	0.137566137566138	1.15136741719589	0.250262583526621	0.686342450100906
GO:0004521	RNA endonuclease activity	11/2227	73/18639	0.150684931506849	1.26116589059549	0.251548024820475	0.688390526168238
GO:0004519	endonuclease activity	18/2227	127/18639	0.141732283464567	1.18623620632962	0.25499625088899	0.694848062034664
GO:0016409	palmitoyltransferase activity	6/2227	36/18639	0.166666666666667	1.39492590929502	0.255538802156723	0.694848062034664
GO:0044390	ubiquitin-like protein conjugating enzyme binding	6/2227	36/18639	0.166666666666667	1.39492590929502	0.255538802156723	0.694848062034664
GO:0005048	signal sequence binding	8/2227	51/18639	0.156862745098039	1.31287144404237	0.260273168225978	0.695519225773137
GO:0016417	S-acyltransferase activity	5/2227	29/18639	0.172413793103448	1.44302680271898	0.260962245928963	0.695519225773137
GO:0035250	UDP-galactosyltransferase activity	5/2227	29/18639	0.172413793103448	1.44302680271898	0.260962245928963	0.695519225773137
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	5/2227	29/18639	0.172413793103448	1.44302680271898	0.260962245928963	0.695519225773137
GO:0004865	protein serine/threonine phosphatase inhibitor activity	3/2227	15/18639	0.2	1.67391109115402	0.263197342230253	0.695519225773137
GO:0008252	nucleotidase activity	3/2227	15/18639	0.2	1.67391109115402	0.263197342230253	0.695519225773137
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/2227	15/18639	0.2	1.67391109115402	0.263197342230253	0.695519225773137
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	3/2227	15/18639	0.2	1.67391109115402	0.263197342230253	0.695519225773137
GO:0047372	monoacylglycerol lipase activity	3/2227	15/18639	0.2	1.67391109115402	0.263197342230253	0.695519225773137
GO:0050780	dopamine receptor binding	3/2227	15/18639	0.2	1.67391109115402	0.263197342230253	0.695519225773137
GO:0051371	muscle alpha-actinin binding	3/2227	15/18639	0.2	1.67391109115402	0.263197342230253	0.695519225773137
GO:0015377	chloride:monoatomic cation symporter activity	4/2227	22/18639	0.181818181818182	1.52173735559456	0.264493226702461	0.695519225773137
GO:0034062	5'-3' RNA polymerase activity	4/2227	22/18639	0.181818181818182	1.52173735559456	0.264493226702461	0.695519225773137
GO:0070034	telomerase RNA binding	4/2227	22/18639	0.181818181818182	1.52173735559456	0.264493226702461	0.695519225773137
GO:0097747	RNA polymerase activity	4/2227	22/18639	0.181818181818182	1.52173735559456	0.264493226702461	0.695519225773137
GO:0140035	ubiquitin-like protein reader activity	4/2227	22/18639	0.181818181818182	1.52173735559456	0.264493226702461	0.695519225773137
GO:0003684	damaged DNA binding	11/2227	74/18639	0.148648648648649	1.24412310829015	0.266091612315884	0.698285586323818
GO:0043014	alpha-tubulin binding	7/2227	44/18639	0.159090909090909	1.33152018614524	0.26846118257819	0.703060228145343
GO:0019955	cytokine binding	20/2227	144/18639	0.138888888888889	1.16243825774585	0.270036669760739	0.705740008086348
GO:0005096	GTPase activator activity	36/2227	271/18639	0.132841328413284	1.11182286497315	0.272970094735739	0.711950573616887
GO:0030159	signaling receptor complex adaptor activity	8/2227	52/18639	0.153846153846154	1.28762391627232	0.278093288149567	0.723835483208037
GO:0070566	adenylyltransferase activity	5/2227	30/18639	0.166666666666667	1.39492590929502	0.284999753036822	0.737095147219854
GO:0001540	amyloid-beta binding	12/2227	83/18639	0.144578313253012	1.21005621047278	0.28532504981849	0.737095147219854
GO:0004714	transmembrane receptor protein tyrosine kinase activity	9/2227	60/18639	0.15	1.25543331836551	0.285494599275296	0.737095147219854
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	9/2227	60/18639	0.15	1.25543331836551	0.285494599275296	0.737095147219854
GO:0140303	intramembrane lipid transporter activity	7/2227	45/18639	0.155555555555556	1.30193084867535	0.287972081646015	0.741992581337917
GO:0005158	insulin receptor binding	4/2227	23/18639	0.173913043478261	1.45557486187306	0.292479831129872	0.748337142342219
GO:0016493	C-C chemokine receptor activity	4/2227	23/18639	0.173913043478261	1.45557486187306	0.292479831129872	0.748337142342219
GO:0070577	lysine-acetylated histone binding	4/2227	23/18639	0.173913043478261	1.45557486187306	0.292479831129872	0.748337142342219
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/2227	16/18639	0.1875	1.56929164795689	0.297461086314435	0.748337142342219
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/2227	16/18639	0.1875	1.56929164795689	0.297461086314435	0.748337142342219
GO:0008142	oxysterol binding	3/2227	16/18639	0.1875	1.56929164795689	0.297461086314435	0.748337142342219
GO:0017070	U6 snRNA binding	3/2227	16/18639	0.1875	1.56929164795689	0.297461086314435	0.748337142342219
GO:0022858	alanine transmembrane transporter activity	3/2227	16/18639	0.1875	1.56929164795689	0.297461086314435	0.748337142342219
GO:0030275	LRR domain binding	3/2227	16/18639	0.1875	1.56929164795689	0.297461086314435	0.748337142342219
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/2227	16/18639	0.1875	1.56929164795689	0.297461086314435	0.748337142342219
GO:0070411	I-SMAD binding	3/2227	16/18639	0.1875	1.56929164795689	0.297461086314435	0.748337142342219
GO:0097027	ubiquitin-protein transferase activator activity	3/2227	16/18639	0.1875	1.56929164795689	0.297461086314435	0.748337142342219
GO:0042887	amide transmembrane transporter activity	6/2227	38/18639	0.157894736842105	1.32150875617423	0.298420865019753	0.749276749499497
GO:0070851	growth factor receptor binding	19/2227	139/18639	0.136690647482014	1.14403995438584	0.301123031928235	0.754578891773105
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	7/2227	46/18639	0.152173913043478	1.27362800413893	0.307796805585287	0.769793185005864
GO:0070273	phosphatidylinositol-4-phosphate binding	5/2227	31/18639	0.161290322580645	1.34992829931776	0.309423582013899	0.770844713087258
GO:0072349	modified amino acid transmembrane transporter activity	5/2227	31/18639	0.161290322580645	1.34992829931776	0.309423582013899	0.770844713087258
GO:0019209	kinase activator activity	20/2227	148/18639	0.135135135135135	1.1310210075365	0.313113848137139	0.771147642484431
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	8/2227	54/18639	0.148148148148148	1.23993414159557	0.314625821294808	0.771147642484431
GO:0140463	chromatin-protein adaptor activity	8/2227	54/18639	0.148148148148148	1.23993414159557	0.314625821294808	0.771147642484431
GO:0003714	transcription corepressor activity	27/2227	204/18639	0.132352941176471	1.10773528091075	0.314741577652054	0.771147642484431
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/2227	39/18639	0.153846153846154	1.28762391627232	0.320358587372088	0.771147642484431
GO:0015295	solute:proton symporter activity	4/2227	24/18639	0.166666666666667	1.39492590929502	0.320821154042169	0.771147642484431
GO:0019957	C-C chemokine binding	4/2227	24/18639	0.166666666666667	1.39492590929502	0.320821154042169	0.771147642484431
GO:0042625	ATPase-coupled ion transmembrane transporter activity	4/2227	24/18639	0.166666666666667	1.39492590929502	0.320821154042169	0.771147642484431
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	4/2227	24/18639	0.166666666666667	1.39492590929502	0.320821154042169	0.771147642484431
GO:0046961	proton-transporting ATPase activity, rotational mechanism	4/2227	24/18639	0.166666666666667	1.39492590929502	0.320821154042169	0.771147642484431
GO:0070840	dynein complex binding	4/2227	24/18639	0.166666666666667	1.39492590929502	0.320821154042169	0.771147642484431
GO:0140033	acetylation-dependent protein binding	4/2227	24/18639	0.166666666666667	1.39492590929502	0.320821154042169	0.771147642484431
GO:0005504	fatty acid binding	7/2227	47/18639	0.148936170212766	1.24652953596576	0.327873110421318	0.771147642484431
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/2227	17/18639	0.176470588235294	1.47698037454766	0.331943248263883	0.771147642484431
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	3/2227	17/18639	0.176470588235294	1.47698037454766	0.331943248263883	0.771147642484431
GO:0017110	nucleoside diphosphate phosphatase activity	3/2227	17/18639	0.176470588235294	1.47698037454766	0.331943248263883	0.771147642484431
GO:0019198	transmembrane receptor protein phosphatase activity	3/2227	17/18639	0.176470588235294	1.47698037454766	0.331943248263883	0.771147642484431
GO:0031489	myosin V binding	3/2227	17/18639	0.176470588235294	1.47698037454766	0.331943248263883	0.771147642484431
GO:0032977	membrane insertase activity	3/2227	17/18639	0.176470588235294	1.47698037454766	0.331943248263883	0.771147642484431
GO:0036041	long-chain fatty acid binding	3/2227	17/18639	0.176470588235294	1.47698037454766	0.331943248263883	0.771147642484431
GO:0046965	nuclear retinoid X receptor binding	3/2227	17/18639	0.176470588235294	1.47698037454766	0.331943248263883	0.771147642484431
GO:0051787	misfolded protein binding	3/2227	17/18639	0.176470588235294	1.47698037454766	0.331943248263883	0.771147642484431
GO:0070402	NADPH binding	3/2227	17/18639	0.176470588235294	1.47698037454766	0.331943248263883	0.771147642484431
GO:0070403	NAD+ binding	3/2227	17/18639	0.176470588235294	1.47698037454766	0.331943248263883	0.771147642484431
GO:0004222	metalloendopeptidase activity	15/2227	110/18639	0.136363636363636	1.14130301669592	0.333266082198213	0.771147642484431
GO:0022884	macromolecule transmembrane transporter activity	5/2227	32/18639	0.15625	1.30774303996408	0.334117211815039	0.771147642484431
GO:0140142	nucleocytoplasmic carrier activity	5/2227	32/18639	0.15625	1.30774303996408	0.334117211815039	0.771147642484431
GO:1901682	sulfur compound transmembrane transporter activity	9/2227	63/18639	0.142857142857143	1.19565077939573	0.337167919141438	0.771147642484431
GO:0140097	catalytic activity, acting on DNA	43/2227	336/18639	0.12797619047619	1.07110382320867	0.338358960537988	0.771147642484431
GO:0004090	carbonyl reductase (NADPH) activity	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0008190	eukaryotic initiation factor 4E binding	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0008239	dipeptidyl-peptidase activity	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0016303	1-phosphatidylinositol-3-kinase activity	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0031434	mitogen-activated protein kinase kinase binding	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0035256	G protein-coupled glutamate receptor binding	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0042166	acetylcholine binding	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0043121	neurotrophin binding	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0043208	glycosphingolipid binding	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0043422	protein kinase B binding	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0045322	unmethylated CpG binding	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0050815	phosphoserine residue binding	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0070097	delta-catenin binding	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0097177	mitochondrial ribosome binding	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:1990757	ubiquitin ligase activator activity	2/2227	10/18639	0.2	1.67391109115402	0.33971527599275	0.771147642484431
GO:0015144	carbohydrate transmembrane transporter activity	6/2227	40/18639	0.15	1.25543331836551	0.342517664256886	0.776130451986348
GO:0140693	molecular condensate scaffold activity	7/2227	48/18639	0.145833333333333	1.22056017063314	0.348139360986011	0.783264270778798
GO:0004709	MAP kinase kinase kinase activity	4/2227	25/18639	0.16	1.33912887292322	0.349343219361436	0.783264270778798
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/2227	25/18639	0.16	1.33912887292322	0.349343219361436	0.783264270778798
GO:0015662	P-type ion transporter activity	4/2227	25/18639	0.16	1.33912887292322	0.349343219361436	0.783264270778798
GO:0042974	nuclear retinoic acid receptor binding	4/2227	25/18639	0.16	1.33912887292322	0.349343219361436	0.783264270778798
GO:0140358	P-type transmembrane transporter activity	4/2227	25/18639	0.16	1.33912887292322	0.349343219361436	0.783264270778798
GO:0019212	phosphatase inhibitor activity	8/2227	56/18639	0.142857142857143	1.19565077939573	0.35202381830064	0.787892188770959
GO:0071889	14-3-3 protein binding	5/2227	33/18639	0.151515151515152	1.26811446299547	0.358968389131821	0.793274550931804
GO:0140311	protein sequestering activity	5/2227	33/18639	0.151515151515152	1.26811446299547	0.358968389131821	0.793274550931804
GO:0140416	transcription regulator inhibitor activity	5/2227	33/18639	0.151515151515152	1.26811446299547	0.358968389131821	0.793274550931804
GO:0004896	cytokine receptor activity	13/2227	96/18639	0.135416666666667	1.1333773013022	0.359383911580627	0.793274550931804
GO:0001727	lipid kinase activity	6/2227	41/18639	0.146341463414634	1.22481299352733	0.364818178798788	0.793274550931804
GO:0140318	protein transporter activity	6/2227	41/18639	0.146341463414634	1.22481299352733	0.364818178798788	0.793274550931804
GO:0000400	four-way junction DNA binding	3/2227	18/18639	0.166666666666667	1.39492590929502	0.366355786687967	0.793274550931804
GO:0000900	mRNA regulatory element binding translation repressor activity	3/2227	18/18639	0.166666666666667	1.39492590929502	0.366355786687967	0.793274550931804
GO:0004706	JUN kinase kinase kinase activity	3/2227	18/18639	0.166666666666667	1.39492590929502	0.366355786687967	0.793274550931804
GO:0030228	lipoprotein particle receptor activity	3/2227	18/18639	0.166666666666667	1.39492590929502	0.366355786687967	0.793274550931804
GO:1990381	ubiquitin-specific protease binding	3/2227	18/18639	0.166666666666667	1.39492590929502	0.366355786687967	0.793274550931804
GO:0004866	endopeptidase inhibitor activity	21/2227	161/18639	0.130434782608696	1.09168114640479	0.368538997993174	0.793274550931804
GO:0001637	G protein-coupled chemoattractant receptor activity	4/2227	26/18639	0.153846153846154	1.28762391627232	0.377883881121897	0.793274550931804
GO:0004950	chemokine receptor activity	4/2227	26/18639	0.153846153846154	1.28762391627232	0.377883881121897	0.793274550931804
GO:0005160	transforming growth factor beta receptor binding	4/2227	26/18639	0.153846153846154	1.28762391627232	0.377883881121897	0.793274550931804
GO:0008143	poly(A) binding	4/2227	26/18639	0.153846153846154	1.28762391627232	0.377883881121897	0.793274550931804
GO:0008198	ferrous iron binding	4/2227	26/18639	0.153846153846154	1.28762391627232	0.377883881121897	0.793274550931804
GO:0030507	spectrin binding	4/2227	26/18639	0.153846153846154	1.28762391627232	0.377883881121897	0.793274550931804
GO:0050681	nuclear androgen receptor binding	4/2227	26/18639	0.153846153846154	1.28762391627232	0.377883881121897	0.793274550931804
GO:0052742	phosphatidylinositol kinase activity	4/2227	26/18639	0.153846153846154	1.28762391627232	0.377883881121897	0.793274550931804
GO:0120014	phospholipid transfer activity	4/2227	26/18639	0.153846153846154	1.28762391627232	0.377883881121897	0.793274550931804
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	34/2227	268/18639	0.126865671641791	1.06180927423949	0.381321468664686	0.793274550931804
GO:0015035	protein-disulfide reductase activity	5/2227	34/18639	0.147058823529412	1.23081697878972	0.383870137070415	0.793274550931804
GO:0019825	oxygen binding	5/2227	34/18639	0.147058823529412	1.23081697878972	0.383870137070415	0.793274550931804
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0000099	sulfur amino acid transmembrane transporter activity	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0002162	dystroglycan binding	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0005114	type II transforming growth factor beta receptor binding	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0008199	ferric iron binding	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0008526	phosphatidylinositol transfer activity	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0010854	adenylate cyclase regulator activity	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0015217	ADP transmembrane transporter activity	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0019206	nucleoside kinase activity	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0019215	intermediate filament binding	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0032050	clathrin heavy chain binding	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0034713	type I transforming growth factor beta receptor binding	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0043522	leucine zipper domain binding	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0050786	RAGE receptor binding	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0050998	nitric-oxide synthase binding	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0070697	activin receptor binding	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0140537	transcription regulator activator activity	2/2227	11/18639	0.181818181818182	1.52173735559456	0.385149092632863	0.793274550931804
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	16/2227	122/18639	0.131147540983607	1.09764661715018	0.385464394466862	0.793274550931804
GO:0005007	fibroblast growth factor receptor activity	7/2227	50/18639	0.14	1.17173776380781	0.389001106065098	0.796704188383325
GO:0005017	platelet-derived growth factor receptor activity	7/2227	50/18639	0.14	1.17173776380781	0.389001106065098	0.796704188383325
GO:0005019	platelet-derived growth factor beta-receptor activity	7/2227	50/18639	0.14	1.17173776380781	0.389001106065098	0.796704188383325
GO:0008514	organic anion transmembrane transporter activity	34/2227	269/18639	0.12639405204461	1.05786202786685	0.390070805763186	0.797616783624563
GO:0030295	protein kinase activator activity	18/2227	139/18639	0.129496402877698	1.08382732520764	0.395475408485203	0.807208326889797
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	3/2227	19/18639	0.157894736842105	1.32150875617423	0.400446071399164	0.807208326889797
GO:0005520	insulin-like growth factor binding	3/2227	19/18639	0.157894736842105	1.32150875617423	0.400446071399164	0.807208326889797
GO:0015245	fatty acid transmembrane transporter activity	3/2227	19/18639	0.157894736842105	1.32150875617423	0.400446071399164	0.807208326889797
GO:0030506	ankyrin binding	3/2227	19/18639	0.157894736842105	1.32150875617423	0.400446071399164	0.807208326889797
GO:0031420	alkali metal ion binding	3/2227	19/18639	0.157894736842105	1.32150875617423	0.400446071399164	0.807208326889797
GO:0034987	immunoglobulin receptor binding	3/2227	19/18639	0.157894736842105	1.32150875617423	0.400446071399164	0.807208326889797
GO:0097001	ceramide binding	3/2227	19/18639	0.157894736842105	1.32150875617423	0.400446071399164	0.807208326889797
GO:0140036	ubiquitin-modified protein reader activity	3/2227	19/18639	0.157894736842105	1.32150875617423	0.400446071399164	0.807208326889797
GO:0008320	protein transmembrane transporter activity	4/2227	27/18639	0.148148148148148	1.23993414159557	0.406293939549042	0.816420840791943
GO:0023026	MHC class II protein complex binding	4/2227	27/18639	0.148148148148148	1.23993414159557	0.406293939549042	0.816420840791943
GO:0010485	histone H4 acetyltransferase activity	5/2227	35/18639	0.142857142857143	1.19565077939573	0.408721559520028	0.816520492551472
GO:0005010	insulin-like growth factor receptor activity	7/2227	51/18639	0.137254901960784	1.14876251353707	0.409480550721322	0.816520492551472
GO:0005030	neurotrophin receptor activity	7/2227	51/18639	0.137254901960784	1.14876251353707	0.409480550721322	0.816520492551472
GO:0016830	carbon-carbon lyase activity	7/2227	51/18639	0.137254901960784	1.14876251353707	0.409480550721322	0.816520492551472
GO:0008200	ion channel inhibitor activity	6/2227	43/18639	0.13953488372093	1.16784494731676	0.409538056123234	0.816520492551472
GO:0005496	steroid binding	14/2227	108/18639	0.12962962962963	1.08494237389612	0.415475796204728	0.827068641043057
GO:0052689	carboxylic ester hydrolase activity	12/2227	92/18639	0.130434782608696	1.09168114640479	0.419542005291738	0.833864203363672
GO:0004527	exonuclease activity	11/2227	84/18639	0.130952380952381	1.09601321444608	0.421616563148972	0.83616195913346
GO:0051536	iron-sulfur cluster binding	10/2227	76/18639	0.131578947368421	1.10125729681185	0.42371001335757	0.83616195913346
GO:0005548	phospholipid transporter activity	9/2227	68/18639	0.132352941176471	1.10773528091075	0.425809461762582	0.83616195913346
GO:0000995	RNA polymerase III general transcription initiation factor activity	2/2227	12/18639	0.166666666666667	1.39492590929502	0.429156822060742	0.83616195913346
GO:0008603	cAMP-dependent protein kinase regulator activity	2/2227	12/18639	0.166666666666667	1.39492590929502	0.429156822060742	0.83616195913346
GO:0010853	cyclase activator activity	2/2227	12/18639	0.166666666666667	1.39492590929502	0.429156822060742	0.83616195913346
GO:0016840	carbon-nitrogen lyase activity	2/2227	12/18639	0.166666666666667	1.39492590929502	0.429156822060742	0.83616195913346
GO:0034452	dynactin binding	2/2227	12/18639	0.166666666666667	1.39492590929502	0.429156822060742	0.83616195913346
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/2227	12/18639	0.166666666666667	1.39492590929502	0.429156822060742	0.83616195913346
GO:0045295	gamma-catenin binding	2/2227	12/18639	0.166666666666667	1.39492590929502	0.429156822060742	0.83616195913346
GO:0070008	serine-type exopeptidase activity	2/2227	12/18639	0.166666666666667	1.39492590929502	0.429156822060742	0.83616195913346
GO:1990817	poly(A) RNA polymerase activity	2/2227	12/18639	0.166666666666667	1.39492590929502	0.429156822060742	0.83616195913346
GO:0016248	channel inhibitor activity	6/2227	44/18639	0.136363636363636	1.14130301669592	0.431813351946137	0.83616195913346
GO:0020037	heme binding	18/2227	142/18639	0.126760563380282	1.06092956481593	0.432323596036946	0.83616195913346
GO:0045505	dynein intermediate chain binding	5/2227	36/18639	0.138888888888889	1.16243825774585	0.433428455868948	0.83616195913346
GO:0000339	RNA cap binding	3/2227	20/18639	0.15	1.25543331836551	0.433996149918057	0.83616195913346
GO:0016004	phospholipase activator activity	3/2227	20/18639	0.15	1.25543331836551	0.433996149918057	0.83616195913346
GO:0016408	C-acyltransferase activity	3/2227	20/18639	0.15	1.25543331836551	0.433996149918057	0.83616195913346
GO:0052745	inositol phosphate phosphatase activity	3/2227	20/18639	0.15	1.25543331836551	0.433996149918057	0.83616195913346
GO:0036408	histone H3K14 acetyltransferase activity	4/2227	28/18639	0.142857142857143	1.19565077939573	0.434437825402674	0.83616195913346
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	4/2227	28/18639	0.142857142857143	1.19565077939573	0.434437825402674	0.83616195913346
GO:0051540	metal cluster binding	10/2227	77/18639	0.12987012987013	1.08695525399612	0.440501574049752	0.84655791223396
GO:0016757	glycosyltransferase activity	33/2227	267/18639	0.123595505617978	1.03443943835361	0.445561299957609	0.854996008026763
GO:0015297	antiporter activity	17/2227	135/18639	0.125925925925926	1.05394402035623	0.44763955267299	0.857696174386928
GO:0004864	protein phosphatase inhibitor activity	7/2227	53/18639	0.132075471698113	1.10541298472435	0.450262931861014	0.858859741669218
GO:0005246	calcium channel regulator activity	7/2227	53/18639	0.132075471698113	1.10541298472435	0.450262931861014	0.858859741669218
GO:0038064	collagen receptor activity	7/2227	53/18639	0.132075471698113	1.10541298472435	0.450262931861014	0.858859741669218
GO:0046906	tetrapyrrole binding	19/2227	152/18639	0.125	1.04619443197126	0.45370715670685	0.860740163903243
GO:0008009	chemokine activity	6/2227	45/18639	0.133333333333333	1.11594072743601	0.453942778146155	0.860740163903243
GO:0051539	4 iron, 4 sulfur cluster binding	6/2227	45/18639	0.133333333333333	1.11594072743601	0.453942778146155	0.860740163903243
GO:0141110	transporter inhibitor activity	6/2227	45/18639	0.133333333333333	1.11594072743601	0.453942778146155	0.860740163903243
GO:0008094	ATP-dependent activity, acting on DNA	26/2227	210/18639	0.123809523809524	1.0362306754763	0.454663481203849	0.86082952441262
GO:0019199	transmembrane receptor protein kinase activity	10/2227	78/18639	0.128205128205128	1.07301993022693	0.457244564617575	0.863163826397991
GO:0030414	peptidase inhibitor activity	21/2227	169/18639	0.124260355029586	1.0400039323738	0.459012032062568	0.863163826397991
GO:0004629	phospholipase C activity	4/2227	29/18639	0.137931034482759	1.15442144217519	0.462193918118467	0.863163826397991
GO:0010484	histone H3 acetyltransferase activity	4/2227	29/18639	0.137931034482759	1.15442144217519	0.462193918118467	0.863163826397991
GO:0043236	laminin binding	4/2227	29/18639	0.137931034482759	1.15442144217519	0.462193918118467	0.863163826397991
GO:0051861	glycolipid binding	4/2227	29/18639	0.137931034482759	1.15442144217519	0.462193918118467	0.863163826397991
GO:0106222	lncRNA binding	4/2227	29/18639	0.137931034482759	1.15442144217519	0.462193918118467	0.863163826397991
GO:0005123	death receptor binding	3/2227	21/18639	0.142857142857143	1.19565077939573	0.466821253146974	0.863163826397991
GO:0009931	calcium-dependent protein serine/threonine kinase activity	3/2227	21/18639	0.142857142857143	1.19565077939573	0.466821253146974	0.863163826397991
GO:0010314	phosphatidylinositol-5-phosphate binding	3/2227	21/18639	0.142857142857143	1.19565077939573	0.466821253146974	0.863163826397991
GO:0019200	carbohydrate kinase activity	3/2227	21/18639	0.142857142857143	1.19565077939573	0.466821253146974	0.863163826397991
GO:0005319	lipid transporter activity	22/2227	178/18639	0.123595505617978	1.03443943835361	0.466972268089096	0.863163826397991
GO:0001217	DNA-binding transcription repressor activity	34/2227	278/18639	0.122302158273381	1.02361469602944	0.469753972034868	0.863163826397991
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/2227	13/18639	0.153846153846154	1.28762391627232	0.471430634448981	0.863163826397991
GO:0008035	high-density lipoprotein particle binding	2/2227	13/18639	0.153846153846154	1.28762391627232	0.471430634448981	0.863163826397991
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/2227	13/18639	0.153846153846154	1.28762391627232	0.471430634448981	0.863163826397991
GO:0031432	titin binding	2/2227	13/18639	0.153846153846154	1.28762391627232	0.471430634448981	0.863163826397991
GO:0031994	insulin-like growth factor I binding	2/2227	13/18639	0.153846153846154	1.28762391627232	0.471430634448981	0.863163826397991
GO:0045159	myosin II binding	2/2227	13/18639	0.153846153846154	1.28762391627232	0.471430634448981	0.863163826397991
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/2227	13/18639	0.153846153846154	1.28762391627232	0.471430634448981	0.863163826397991
GO:0089720	caspase binding	2/2227	13/18639	0.153846153846154	1.28762391627232	0.471430634448981	0.863163826397991
GO:0097157	pre-mRNA intronic binding	2/2227	13/18639	0.153846153846154	1.28762391627232	0.471430634448981	0.863163826397991
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/2227	13/18639	0.153846153846154	1.28762391627232	0.471430634448981	0.863163826397991
GO:0016835	carbon-oxygen lyase activity	10/2227	79/18639	0.126582278481013	1.05943739946457	0.473910723871207	0.866463383558517
GO:0004180	carboxypeptidase activity	6/2227	46/18639	0.130434782608696	1.09168114640479	0.475864674030285	0.868792933443863
GO:0140299	molecular sensor activity	9/2227	71/18639	0.126760563380282	1.06092956481593	0.478862678315061	0.873019262320468
GO:0016407	acetyltransferase activity	12/2227	96/18639	0.125	1.04619443197126	0.480283123465398	0.8743615837447
GO:0046943	carboxylic acid transmembrane transporter activity	23/2227	188/18639	0.122340425531915	1.02393497597187	0.485344344395535	0.874383028106497
GO:0008106	alcohol dehydrogenase (NADP+) activity	4/2227	30/18639	0.133333333333333	1.11594072743601	0.489454558900259	0.874383028106497
GO:0016769	transferase activity, transferring nitrogenous groups	4/2227	30/18639	0.133333333333333	1.11594072743601	0.489454558900259	0.874383028106497
GO:0031624	ubiquitin conjugating enzyme binding	4/2227	30/18639	0.133333333333333	1.11594072743601	0.489454558900259	0.874383028106497
GO:0043995	histone H4K5 acetyltransferase activity	4/2227	30/18639	0.133333333333333	1.11594072743601	0.489454558900259	0.874383028106497
GO:0043996	histone H4K8 acetyltransferase activity	4/2227	30/18639	0.133333333333333	1.11594072743601	0.489454558900259	0.874383028106497
GO:0043997	histone H4K12 acetyltransferase activity	4/2227	30/18639	0.133333333333333	1.11594072743601	0.489454558900259	0.874383028106497
GO:0033218	amide binding	30/2227	247/18639	0.121457489878543	1.0165451970571	0.491151713420455	0.874383028106497
GO:0005342	organic acid transmembrane transporter activity	23/2227	189/18639	0.121693121693122	1.01851733059636	0.496114416327018	0.874383028106497
GO:0042379	chemokine receptor binding	9/2227	72/18639	0.125	1.04619443197126	0.49632056014574	0.874383028106497
GO:0140767	enzyme-substrate adaptor activity	17/2227	139/18639	0.122302158273381	1.02361469602944	0.498092804067179	0.874383028106497
GO:0008093	cytoskeletal anchor activity	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0032931	histone H3K56 acetyltransferase activity	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0033691	sialic acid binding	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0043992	histone H3K9 acetyltransferase activity	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0043993	histone H3K18 acetyltransferase activity	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0043994	histone H3K23 acetyltransferase activity	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0043999	histone H2AK5 acetyltransferase activity	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0044012	histone H2AK9 acetyltransferase activity	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0044014	histone H2BK5 acetyltransferase activity	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0044015	histone H2BK12 acetyltransferase activity	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0044016	histone H3K4 acetyltransferase activity	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0044017	histone H3K27 acetyltransferase activity	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0044018	histone H3K36 acetyltransferase activity	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0046972	histone H4K16 acetyltransferase activity	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0140908	histone H3K122 acetyltransferase activity	3/2227	22/18639	0.136363636363636	1.14130301669592	0.498767783638213	0.874383028106497
GO:0004536	DNA nuclease activity	8/2227	64/18639	0.125	1.04619443197126	0.502845806923669	0.877885735239074
GO:0140030	modification-dependent protein binding	21/2227	173/18639	0.121387283236994	1.01595759867729	0.504212319813468	0.877885735239074
GO:0005516	calmodulin binding	25/2227	207/18639	0.120772946859903	1.01081587630074	0.509270911868751	0.877885735239074
GO:0042626	ATPase-coupled transmembrane transporter activity	12/2227	98/18639	0.122448979591837	1.02484352519634	0.510239058452754	0.877885735239074
GO:0004705	JUN kinase activity	2/2227	14/18639	0.142857142857143	1.19565077939573	0.511756551450008	0.877885735239074
GO:0005161	platelet-derived growth factor receptor binding	2/2227	14/18639	0.142857142857143	1.19565077939573	0.511756551450008	0.877885735239074
GO:0005347	ATP transmembrane transporter activity	2/2227	14/18639	0.142857142857143	1.19565077939573	0.511756551450008	0.877885735239074
GO:0008474	palmitoyl-(protein) hydrolase activity	2/2227	14/18639	0.142857142857143	1.19565077939573	0.511756551450008	0.877885735239074
GO:0019763	immunoglobulin receptor activity	2/2227	14/18639	0.142857142857143	1.19565077939573	0.511756551450008	0.877885735239074
GO:0019992	diacylglycerol binding	2/2227	14/18639	0.142857142857143	1.19565077939573	0.511756551450008	0.877885735239074
GO:0042043	neurexin family protein binding	2/2227	14/18639	0.142857142857143	1.19565077939573	0.511756551450008	0.877885735239074
GO:0046030	inositol trisphosphate phosphatase activity	2/2227	14/18639	0.142857142857143	1.19565077939573	0.511756551450008	0.877885735239074
GO:0071933	Arp2/3 complex binding	2/2227	14/18639	0.142857142857143	1.19565077939573	0.511756551450008	0.877885735239074
GO:0098599	palmitoyl hydrolase activity	2/2227	14/18639	0.142857142857143	1.19565077939573	0.511756551450008	0.877885735239074
GO:1901474	azole transmembrane transporter activity	2/2227	14/18639	0.142857142857143	1.19565077939573	0.511756551450008	0.877885735239074
GO:1901612	cardiolipin binding	2/2227	14/18639	0.142857142857143	1.19565077939573	0.511756551450008	0.877885735239074
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	16/2227	132/18639	0.121212121212121	1.01449157039638	0.515630848575717	0.883010430029026
GO:0005452	solute:inorganic anion antiporter activity	4/2227	31/18639	0.129032258064516	1.07994263945421	0.516125814735276	0.883010430029026
GO:0016879	ligase activity, forming carbon-nitrogen bonds	6/2227	48/18639	0.125	1.04619443197126	0.518862349598388	0.886505458271043
GO:0016829	lyase activity	24/2227	200/18639	0.12	1.00434665469241	0.523751666050041	0.893664391471231
GO:0050997	quaternary ammonium group binding	5/2227	40/18639	0.125	1.04619443197126	0.529181602134852	0.894796553109662
GO:0017134	fibroblast growth factor binding	3/2227	23/18639	0.130434782608696	1.09168114640479	0.529710976514463	0.894796553109662
GO:0031681	G-protein beta-subunit binding	3/2227	23/18639	0.130434782608696	1.09168114640479	0.529710976514463	0.894796553109662
GO:0044013	histone H2B acetyltransferase activity	3/2227	23/18639	0.130434782608696	1.09168114640479	0.529710976514463	0.894796553109662
GO:0099186	structural constituent of postsynapse	3/2227	23/18639	0.130434782608696	1.09168114640479	0.529710976514463	0.894796553109662
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	3/2227	23/18639	0.130434782608696	1.09168114640479	0.529710976514463	0.894796553109662
GO:0019842	vitamin binding	18/2227	150/18639	0.12	1.00434665469241	0.529931729862578	0.894796553109662
GO:0003678	DNA helicase activity	9/2227	74/18639	0.121621621621622	1.01791890678285	0.530716578448454	0.894796553109662
GO:0035064	methylated histone binding	9/2227	74/18639	0.121621621621622	1.01791890678285	0.530716578448454	0.894796553109662
GO:0005004	GPI-linked ephrin receptor activity	6/2227	49/18639	0.122448979591837	1.02484352519634	0.539838255596298	0.898324597203215
GO:0005008	hepatocyte growth factor receptor activity	6/2227	49/18639	0.122448979591837	1.02484352519634	0.539838255596298	0.898324597203215
GO:0005009	insulin receptor activity	6/2227	49/18639	0.122448979591837	1.02484352519634	0.539838255596298	0.898324597203215
GO:0005011	macrophage colony-stimulating factor receptor activity	6/2227	49/18639	0.122448979591837	1.02484352519634	0.539838255596298	0.898324597203215
GO:0005018	platelet-derived growth factor alpha-receptor activity	6/2227	49/18639	0.122448979591837	1.02484352519634	0.539838255596298	0.898324597203215
GO:0005020	stem cell factor receptor activity	6/2227	49/18639	0.122448979591837	1.02484352519634	0.539838255596298	0.898324597203215
GO:0008288	boss receptor activity	6/2227	49/18639	0.122448979591837	1.02484352519634	0.539838255596298	0.898324597203215
GO:0036332	placental growth factor receptor activity	6/2227	49/18639	0.122448979591837	1.02484352519634	0.539838255596298	0.898324597203215
GO:0038062	protein tyrosine kinase collagen receptor activity	6/2227	49/18639	0.122448979591837	1.02484352519634	0.539838255596298	0.898324597203215
GO:0060175	brain-derived neurotrophic factor receptor activity	6/2227	49/18639	0.122448979591837	1.02484352519634	0.539838255596298	0.898324597203215
GO:0071813	lipoprotein particle binding	4/2227	32/18639	0.125	1.04619443197126	0.54212704372388	0.899790080362492
GO:0071814	protein-lipid complex binding	4/2227	32/18639	0.125	1.04619443197126	0.54212704372388	0.899790080362492
GO:0017116	single-stranded DNA helicase activity	7/2227	58/18639	0.120689655172414	1.01011876190329	0.548956942264683	0.901147996504549
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/2227	15/18639	0.133333333333333	1.11594072743601	0.549996429791509	0.901147996504549
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/2227	15/18639	0.133333333333333	1.11594072743601	0.549996429791509	0.901147996504549
GO:0005041	low-density lipoprotein particle receptor activity	2/2227	15/18639	0.133333333333333	1.11594072743601	0.549996429791509	0.901147996504549
GO:0005402	carbohydrate:monoatomic cation symporter activity	2/2227	15/18639	0.133333333333333	1.11594072743601	0.549996429791509	0.901147996504549
GO:0031005	filamin binding	2/2227	15/18639	0.133333333333333	1.11594072743601	0.549996429791509	0.901147996504549
GO:0140161	monocarboxylate:sodium symporter activity	2/2227	15/18639	0.133333333333333	1.11594072743601	0.549996429791509	0.901147996504549
GO:0140776	protein-containing complex destabilizing activity	2/2227	15/18639	0.133333333333333	1.11594072743601	0.549996429791509	0.901147996504549
GO:0141050	histone H3K deacetylase activity	2/2227	15/18639	0.133333333333333	1.11594072743601	0.549996429791509	0.901147996504549
GO:0141051	histone H4K deacetylase activity	2/2227	15/18639	0.133333333333333	1.11594072743601	0.549996429791509	0.901147996504549
GO:0022853	active monoatomic ion transmembrane transporter activity	14/2227	118/18639	0.11864406779661	0.992998104921876	0.553761558718696	0.904293045549136
GO:0042054	histone methyltransferase activity	8/2227	67/18639	0.119402985074627	0.999349905166579	0.556999561688242	0.904293045549136
GO:0050840	extracellular matrix binding	8/2227	67/18639	0.119402985074627	0.999349905166579	0.556999561688242	0.904293045549136
GO:0004622	lysophospholipase activity	3/2227	24/18639	0.125	1.04619443197126	0.559552379724791	0.904293045549136
GO:0005315	phosphate transmembrane transporter activity	3/2227	24/18639	0.125	1.04619443197126	0.559552379724791	0.904293045549136
GO:0035035	histone acetyltransferase binding	3/2227	24/18639	0.125	1.04619443197126	0.559552379724791	0.904293045549136
GO:0043998	histone H2A acetyltransferase activity	3/2227	24/18639	0.125	1.04619443197126	0.559552379724791	0.904293045549136
GO:0050699	WW domain binding	3/2227	24/18639	0.125	1.04619443197126	0.559552379724791	0.904293045549136
GO:0060229	lipase activator activity	3/2227	24/18639	0.125	1.04619443197126	0.559552379724791	0.904293045549136
GO:0070300	phosphatidic acid binding	3/2227	24/18639	0.125	1.04619443197126	0.559552379724791	0.904293045549136
GO:0005006	epidermal growth factor receptor activity	6/2227	50/18639	0.12	1.00434665469241	0.560406957805099	0.904293045549136
GO:0015605	organophosphate ester transmembrane transporter activity	6/2227	50/18639	0.12	1.00434665469241	0.560406957805099	0.904293045549136
GO:0140034	methylation-dependent protein binding	9/2227	76/18639	0.118421052631579	0.991131567130669	0.564242809177665	0.909334565105997
GO:0019956	chemokine binding	4/2227	33/18639	0.121212121212121	1.01449157039638	0.567390306426233	0.910490739952757
GO:0015459	potassium channel regulator activity	7/2227	59/18639	0.11864406779661	0.992998104921876	0.567809952850037	0.910490739952757
GO:0031593	polyubiquitin modification-dependent protein binding	7/2227	59/18639	0.11864406779661	0.992998104921876	0.567809952850037	0.910490739952757
GO:0036002	pre-mRNA binding	7/2227	59/18639	0.11864406779661	0.992998104921876	0.567809952850037	0.910490739952757
GO:0004402	histone acetyltransferase activity	5/2227	42/18639	0.119047619047619	0.99637564949644	0.574283762303104	0.916604535411867
GO:0019894	kinesin binding	5/2227	42/18639	0.119047619047619	0.99637564949644	0.574283762303104	0.916604535411867
GO:0042056	chemoattractant activity	5/2227	42/18639	0.119047619047619	0.99637564949644	0.574283762303104	0.916604535411867
GO:0003777	microtubule motor activity	8/2227	68/18639	0.117647058823529	0.984653583031776	0.574491575011663	0.916604535411867
GO:0005021	vascular endothelial growth factor receptor activity	6/2227	51/18639	0.117647058823529	0.984653583031776	0.580530478749602	0.922382410996951
GO:0000062	fatty-acyl-CoA binding	2/2227	16/18639	0.125	1.04619443197126	0.58607290743109	0.922382410996951
GO:0003688	DNA replication origin binding	2/2227	16/18639	0.125	1.04619443197126	0.58607290743109	0.922382410996951
GO:0004707	MAP kinase activity	2/2227	16/18639	0.125	1.04619443197126	0.58607290743109	0.922382410996951
GO:0005149	interleukin-1 receptor binding	2/2227	16/18639	0.125	1.04619443197126	0.58607290743109	0.922382410996951
GO:0008296	3'-5'-DNA exonuclease activity	2/2227	16/18639	0.125	1.04619443197126	0.58607290743109	0.922382410996951
GO:0015378	sodium:chloride symporter activity	2/2227	16/18639	0.125	1.04619443197126	0.58607290743109	0.922382410996951
GO:0140328	floppase activity	2/2227	16/18639	0.125	1.04619443197126	0.58607290743109	0.922382410996951
GO:0000030	mannosyltransferase activity	3/2227	25/18639	0.12	1.00434665469241	0.588217265228885	0.922382410996951
GO:0005537	D-mannose binding	3/2227	25/18639	0.12	1.00434665469241	0.588217265228885	0.922382410996951
GO:0008139	nuclear localization sequence binding	3/2227	25/18639	0.12	1.00434665469241	0.588217265228885	0.922382410996951
GO:0019706	protein-cysteine S-palmitoyltransferase activity	3/2227	25/18639	0.12	1.00434665469241	0.588217265228885	0.922382410996951
GO:0019707	protein-cysteine S-acyltransferase activity	3/2227	25/18639	0.12	1.00434665469241	0.588217265228885	0.922382410996951
GO:0047617	fatty acyl-CoA hydrolase activity	3/2227	25/18639	0.12	1.00434665469241	0.588217265228885	0.922382410996951
GO:0008276	protein methyltransferase activity	11/2227	95/18639	0.115789473684211	0.969106421194432	0.591634789285262	0.923561231344271
GO:0016831	carboxy-lyase activity	4/2227	34/18639	0.117647058823529	0.984653583031776	0.591859662340342	0.923561231344271
GO:0051427	hormone receptor binding	4/2227	34/18639	0.117647058823529	0.984653583031776	0.591859662340342	0.923561231344271
GO:0052866	phosphatidylinositol phosphate phosphatase activity	4/2227	34/18639	0.117647058823529	0.984653583031776	0.591859662340342	0.923561231344271
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	14/2227	122/18639	0.114754098360656	0.960440790006404	0.605957613540882	0.940979655129485
GO:0008028	monocarboxylic acid transmembrane transporter activity	8/2227	70/18639	0.114285714285714	0.956520623516582	0.608485531138112	0.940979655129485
GO:0033293	monocarboxylic acid binding	9/2227	79/18639	0.113924050632911	0.953493659518112	0.612501656589782	0.940979655129485
GO:0034061	DNA polymerase activity	4/2227	35/18639	0.114285714285714	0.956520623516582	0.615490385284899	0.940979655129485
GO:0140566	histone reader activity	4/2227	35/18639	0.114285714285714	0.956520623516582	0.615490385284899	0.940979655129485
GO:0004435	phosphatidylinositol phospholipase C activity	3/2227	26/18639	0.115384615384615	0.965717937204242	0.615652054460232	0.940979655129485
GO:0004529	DNA exonuclease activity	3/2227	26/18639	0.115384615384615	0.965717937204242	0.615652054460232	0.940979655129485
GO:0005112	Notch binding	3/2227	26/18639	0.115384615384615	0.965717937204242	0.615652054460232	0.940979655129485
GO:0016289	acyl-CoA hydrolase activity	3/2227	26/18639	0.115384615384615	0.965717937204242	0.615652054460232	0.940979655129485
GO:0016651	oxidoreductase activity, acting on NAD(P)H	10/2227	88/18639	0.113636363636364	0.951085847246602	0.616409555465345	0.940979655129485
GO:0001223	transcription coactivator binding	5/2227	44/18639	0.113636363636364	0.951085847246602	0.61700537723387	0.940979655129485
GO:0019205	nucleobase-containing compound kinase activity	5/2227	44/18639	0.113636363636364	0.951085847246602	0.61700537723387	0.940979655129485
GO:0005003	ephrin receptor activity	6/2227	53/18639	0.113207547169811	0.947496844049445	0.619313286396393	0.940979655129485
GO:0005005	transmembrane-ephrin receptor activity	6/2227	53/18639	0.113207547169811	0.947496844049445	0.619313286396393	0.940979655129485
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/2227	17/18639	0.117647058823529	0.984653583031776	0.619956861986718	0.940979655129485
GO:0004550	nucleoside diphosphate kinase activity	2/2227	17/18639	0.117647058823529	0.984653583031776	0.619956861986718	0.940979655129485
GO:0008429	phosphatidylethanolamine binding	2/2227	17/18639	0.117647058823529	0.984653583031776	0.619956861986718	0.940979655129485
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/2227	17/18639	0.117647058823529	0.984653583031776	0.619956861986718	0.940979655129485
GO:0016018	cyclosporin A binding	2/2227	17/18639	0.117647058823529	0.984653583031776	0.619956861986718	0.940979655129485
GO:0030169	low-density lipoprotein particle binding	2/2227	17/18639	0.117647058823529	0.984653583031776	0.619956861986718	0.940979655129485
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/2227	17/18639	0.117647058823529	0.984653583031776	0.619956861986718	0.940979655129485
GO:1901567	fatty acid derivative binding	2/2227	17/18639	0.117647058823529	0.984653583031776	0.619956861986718	0.940979655129485
GO:1990226	histone methyltransferase binding	2/2227	17/18639	0.117647058823529	0.984653583031776	0.619956861986718	0.940979655129485
GO:0016874	ligase activity	19/2227	167/18639	0.11377245508982	0.952224872213364	0.626062735498809	0.949120018941254
GO:0008170	N-methyltransferase activity	11/2227	98/18639	0.112244897959184	0.939439898096643	0.634112653475695	0.960184799931207
GO:0042605	peptide antigen binding	5/2227	45/18639	0.111111111111111	0.929950606196677	0.637388202119835	0.961888096247995
GO:0050661	NADP binding	6/2227	54/18639	0.111111111111111	0.929950606196677	0.637919421740008	0.961888096247995
GO:0004033	aldo-keto reductase (NADPH) activity	4/2227	36/18639	0.111111111111111	0.929950606196677	0.638248126461893	0.961888096247995
GO:0004869	cysteine-type endopeptidase inhibitor activity	4/2227	36/18639	0.111111111111111	0.929950606196677	0.638248126461893	0.961888096247995
GO:0004683	calcium/calmodulin-dependent protein kinase activity	3/2227	27/18639	0.111111111111111	0.929950606196677	0.64182181882413	0.962732728236195
GO:0005044	scavenger receptor activity	3/2227	27/18639	0.111111111111111	0.929950606196677	0.64182181882413	0.962732728236195
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	3/2227	27/18639	0.111111111111111	0.929950606196677	0.64182181882413	0.962732728236195
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	3/2227	27/18639	0.111111111111111	0.929950606196677	0.64182181882413	0.962732728236195
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/2227	18/18639	0.111111111111111	0.929950606196677	0.651656996399062	0.968392606276746
GO:0008308	voltage-gated monoatomic anion channel activity	2/2227	18/18639	0.111111111111111	0.929950606196677	0.651656996399062	0.968392606276746
GO:0008525	phosphatidylcholine transporter activity	2/2227	18/18639	0.111111111111111	0.929950606196677	0.651656996399062	0.968392606276746
GO:0015172	acidic amino acid transmembrane transporter activity	2/2227	18/18639	0.111111111111111	0.929950606196677	0.651656996399062	0.968392606276746
GO:0015373	monoatomic anion:sodium symporter activity	2/2227	18/18639	0.111111111111111	0.929950606196677	0.651656996399062	0.968392606276746
GO:0016854	racemase and epimerase activity	2/2227	18/18639	0.111111111111111	0.929950606196677	0.651656996399062	0.968392606276746
GO:0017075	syntaxin-1 binding	2/2227	18/18639	0.111111111111111	0.929950606196677	0.651656996399062	0.968392606276746
GO:0050811	GABA receptor binding	2/2227	18/18639	0.111111111111111	0.929950606196677	0.651656996399062	0.968392606276746
GO:0005178	integrin binding	18/2227	161/18639	0.111801242236025	0.935726696918396	0.654733824941949	0.970462989411807
GO:0030276	clathrin binding	5/2227	46/18639	0.108695652173913	0.909734288670662	0.657086193350267	0.970462989411807
GO:0019213	deacetylase activity	4/2227	37/18639	0.108108108108108	0.904816806029199	0.660108049376329	0.970462989411807
GO:0022829	wide pore channel activity	4/2227	37/18639	0.108108108108108	0.904816806029199	0.660108049376329	0.970462989411807
GO:0023023	MHC protein complex binding	4/2227	37/18639	0.108108108108108	0.904816806029199	0.660108049376329	0.970462989411807
GO:0042805	actinin binding	4/2227	37/18639	0.108108108108108	0.904816806029199	0.660108049376329	0.970462989411807
GO:1901681	sulfur compound binding	31/2227	275/18639	0.112727272727273	0.943477160468629	0.663706921394137	0.970462989411807
GO:0042277	peptide binding	28/2227	249/18639	0.112449799196787	0.941154830367721	0.663779309604313	0.970462989411807
GO:0016758	hexosyltransferase activity	22/2227	197/18639	0.111675126903553	0.934671167649452	0.665531554074951	0.970462989411807
GO:0046966	nuclear thyroid hormone receptor binding	3/2227	28/18639	0.107142857142857	0.896738084546796	0.666707898034705	0.970462989411807
GO:0051393	alpha-actinin binding	3/2227	28/18639	0.107142857142857	0.896738084546796	0.666707898034705	0.970462989411807
GO:0051537	2 iron, 2 sulfur cluster binding	3/2227	28/18639	0.107142857142857	0.896738084546796	0.666707898034705	0.970462989411807
GO:0008194	UDP-glycosyltransferase activity	16/2227	145/18639	0.110344827586207	0.923537153740148	0.671206501467833	0.970462989411807
GO:0038024	cargo receptor activity	7/2227	65/18639	0.107692307692308	0.901336741390626	0.672259427300841	0.970462989411807
GO:0160215	deacylase activity	7/2227	65/18639	0.107692307692308	0.901336741390626	0.672259427300841	0.970462989411807
GO:0005506	iron ion binding	17/2227	154/18639	0.11038961038961	0.923911965896699	0.673356108421355	0.970462989411807
GO:0170055	lipid transmembrane transporter activity	6/2227	56/18639	0.107142857142857	0.896738084546796	0.673459996149729	0.970462989411807
GO:0061733	protein-lysine-acetyltransferase activity	5/2227	47/18639	0.106382978723404	0.890378239975542	0.676081933508413	0.970462989411807
GO:0140938	histone H3 methyltransferase activity	5/2227	47/18639	0.106382978723404	0.890378239975542	0.676081933508413	0.970462989411807
GO:1990518	single-stranded 3'-5' DNA helicase activity	5/2227	47/18639	0.106382978723404	0.890378239975542	0.676081933508413	0.970462989411807
GO:0000146	microfilament motor activity	4/2227	38/18639	0.105263157894737	0.881005837449484	0.681053956622824	0.970462989411807
GO:0005109	frizzled binding	4/2227	38/18639	0.105263157894737	0.881005837449484	0.681053956622824	0.970462989411807
GO:0005229	intracellularly calcium-gated chloride channel activity	2/2227	19/18639	0.105263157894737	0.881005837449484	0.681211222869638	0.970462989411807
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/2227	19/18639	0.105263157894737	0.881005837449484	0.681211222869638	0.970462989411807
GO:0008381	mechanosensitive monoatomic ion channel activity	2/2227	19/18639	0.105263157894737	0.881005837449484	0.681211222869638	0.970462989411807
GO:0008574	plus-end-directed microtubule motor activity	2/2227	19/18639	0.105263157894737	0.881005837449484	0.681211222869638	0.970462989411807
GO:0042577	lipid phosphatase activity	2/2227	19/18639	0.105263157894737	0.881005837449484	0.681211222869638	0.970462989411807
GO:0042800	histone H3K4 methyltransferase activity	2/2227	19/18639	0.105263157894737	0.881005837449484	0.681211222869638	0.970462989411807
GO:0046527	glucosyltransferase activity	2/2227	19/18639	0.105263157894737	0.881005837449484	0.681211222869638	0.970462989411807
GO:0046624	sphingolipid transporter activity	2/2227	19/18639	0.105263157894737	0.881005837449484	0.681211222869638	0.970462989411807
GO:0120227	acyl-CoA binding	2/2227	19/18639	0.105263157894737	0.881005837449484	0.681211222869638	0.970462989411807
GO:0141147	intracellularly calcium-gated channel activity	2/2227	19/18639	0.105263157894737	0.881005837449484	0.681211222869638	0.970462989411807
GO:1990380	K48-linked deubiquitinase activity	2/2227	19/18639	0.105263157894737	0.881005837449484	0.681211222869638	0.970462989411807
GO:0015291	secondary active transmembrane transporter activity	32/2227	287/18639	0.111498257839721	0.9331908522113	0.689673942951669	0.970462989411807
GO:0015932	nucleobase-containing compound transmembrane transporter activity	6/2227	57/18639	0.105263157894737	0.881005837449484	0.690365790901493	0.970462989411807
GO:0043138	3'-5' DNA helicase activity	5/2227	48/18639	0.104166666666667	0.871828693309385	0.694363280474695	0.970462989411807
GO:0016410	N-acyltransferase activity	10/2227	94/18639	0.106382978723404	0.890378239975542	0.699480660664789	0.970462989411807
GO:0042562	hormone binding	10/2227	94/18639	0.106382978723404	0.890378239975542	0.699480660664789	0.970462989411807
GO:0015108	chloride transmembrane transporter activity	13/2227	121/18639	0.107438016528926	0.899208437396787	0.700195301480488	0.970462989411807
GO:0000217	DNA secondary structure binding	4/2227	39/18639	0.102564102564103	0.858415944181548	0.701077424819706	0.970462989411807
GO:0016776	phosphotransferase activity, phosphate group as acceptor	4/2227	39/18639	0.102564102564103	0.858415944181548	0.701077424819706	0.970462989411807
GO:0030246	carbohydrate binding	31/2227	280/18639	0.110714285714286	0.926629354031689	0.70272228152598	0.970462989411807
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	7/2227	67/18639	0.104477611940299	0.874431167020756	0.703333647923638	0.970462989411807
GO:0015399	primary active transmembrane transporter activity	18/2227	166/18639	0.108433734939759	0.907542157854589	0.705363751849768	0.970462989411807
GO:0001972	retinoic acid binding	2/2227	20/18639	0.1	0.836955545577009	0.708679564308703	0.970462989411807
GO:0010851	cyclase regulator activity	2/2227	20/18639	0.1	0.836955545577009	0.708679564308703	0.970462989411807
GO:0015464	acetylcholine receptor activity	2/2227	20/18639	0.1	0.836955545577009	0.708679564308703	0.970462989411807
GO:0016505	peptidase activator activity involved in apoptotic process	2/2227	20/18639	0.1	0.836955545577009	0.708679564308703	0.970462989411807
GO:0035254	glutamate receptor binding	5/2227	49/18639	0.102040816326531	0.854036270996948	0.711922942392695	0.970462989411807
GO:0031210	phosphatidylcholine binding	3/2227	30/18639	0.1	0.836955545577009	0.71262245450899	0.970462989411807
GO:0033612	receptor serine/threonine kinase binding	3/2227	30/18639	0.1	0.836955545577009	0.71262245450899	0.970462989411807
GO:0051721	protein phosphatase 2A binding	3/2227	30/18639	0.1	0.836955545577009	0.71262245450899	0.970462989411807
GO:0098918	structural constituent of synapse	3/2227	30/18639	0.1	0.836955545577009	0.71262245450899	0.970462989411807
GO:0140223	general transcription initiation factor activity	7/2227	68/18639	0.102941176470588	0.861571885152804	0.71811880383157	0.970462989411807
GO:0000182	rDNA binding	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0004382	GDP phosphatase activity	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0004935	adrenergic receptor activity	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0004955	prostaglandin receptor activity	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0005337	nucleoside transmembrane transporter activity	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0005381	iron ion transmembrane transporter activity	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0008140	cAMP response element binding protein binding	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0015643	toxic substance binding	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0019911	structural constituent of myelin sheath	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0031419	cobalamin binding	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0032052	bile acid binding	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0042975	peroxisome proliferator activated receptor binding	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0043295	glutathione binding	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0051864	histone H3K36 demethylase activity	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0140135	mechanosensitive monoatomic cation channel activity	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0140999	histone H3K4 trimethyltransferase activity	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0141109	transporter activator activity	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/2227	10/18639	0.1	0.836955545577009	0.719942845709127	0.970462989411807
GO:0008080	N-acetyltransferase activity	7/2227	69/18639	0.101449275362319	0.849085336092618	0.732396303548471	0.970462989411807
GO:0016279	protein-lysine N-methyltransferase activity	7/2227	69/18639	0.101449275362319	0.849085336092618	0.732396303548471	0.970462989411807
GO:0005310	dicarboxylic acid transmembrane transporter activity	3/2227	31/18639	0.0967741935483871	0.809956979590654	0.733675665913316	0.970462989411807
GO:0016878	acid-thiol ligase activity	3/2227	31/18639	0.0967741935483871	0.809956979590654	0.733675665913316	0.970462989411807
GO:0008373	sialyltransferase activity	2/2227	21/18639	0.0952380952380952	0.797100519597152	0.734138333904675	0.970462989411807
GO:0009975	cyclase activity	2/2227	21/18639	0.0952380952380952	0.797100519597152	0.734138333904675	0.970462989411807
GO:0051010	microtubule plus-end binding	2/2227	21/18639	0.0952380952380952	0.797100519597152	0.734138333904675	0.970462989411807
GO:0140312	cargo adaptor activity	2/2227	21/18639	0.0952380952380952	0.797100519597152	0.734138333904675	0.970462989411807
GO:0008234	cysteine-type peptidase activity	20/2227	187/18639	0.106951871657754	0.895139620937978	0.734787413870772	0.970462989411807
GO:0098531	ligand-modulated transcription factor activity	6/2227	60/18639	0.1	0.836955545577009	0.737527354798151	0.970462989411807
GO:0001530	lipopolysaccharide binding	4/2227	41/18639	0.0975609756097561	0.816541995684887	0.73835718827332	0.970462989411807
GO:0015294	solute:monoatomic cation symporter activity	12/2227	116/18639	0.103448275862069	0.865816081631389	0.74460245330124	0.970462989411807
GO:0016597	amino acid binding	5/2227	51/18639	0.0980392156862745	0.82054465252648	0.744869744513242	0.970462989411807
GO:0016278	lysine N-methyltransferase activity	7/2227	70/18639	0.1	0.836955545577009	0.746164167149622	0.970462989411807
GO:0015026	coreceptor activity	6/2227	61/18639	0.0983606557377049	0.823234962862632	0.752053706591519	0.970462989411807
GO:0019905	syntaxin binding	6/2227	61/18639	0.0983606557377049	0.823234962862632	0.752053706591519	0.970462989411807
GO:0004016	adenylate cyclase activity	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0004954	prostanoid receptor activity	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0008046	axon guidance receptor activity	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0008271	secondary active sulfate transmembrane transporter activity	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0008432	JUN kinase binding	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0008503	benzodiazepine receptor activity	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0019107	myristoyltransferase activity	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0019864	IgG binding	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0047676	arachidonate-CoA ligase activity	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0048407	platelet-derived growth factor binding	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0097493	structural molecule activity conferring elasticity	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0180030	inositol phosphate kinase activity	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:1900750	oligopeptide binding	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:1990948	ubiquitin ligase inhibitor activity	1/2227	11/18639	0.0909090909090909	0.760868677797281	0.753422221016754	0.970462989411807
GO:0015106	bicarbonate transmembrane transporter activity	3/2227	32/18639	0.09375	0.784645823978446	0.753491040622568	0.970462989411807
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	3/2227	32/18639	0.09375	0.784645823978446	0.753491040622568	0.970462989411807
GO:0004520	DNA endonuclease activity	4/2227	42/18639	0.0952380952380952	0.797100519597152	0.755628075217553	0.970462989411807
GO:0004407	histone deacetylase activity	2/2227	22/18639	0.0909090909090909	0.760868677797281	0.757675388931321	0.970462989411807
GO:0031683	G-protein beta/gamma-subunit complex binding	2/2227	22/18639	0.0909090909090909	0.760868677797281	0.757675388931321	0.970462989411807
GO:0033558	protein lysine deacetylase activity	2/2227	22/18639	0.0909090909090909	0.760868677797281	0.757675388931321	0.970462989411807
GO:0140784	metal ion sensor activity	2/2227	22/18639	0.0909090909090909	0.760868677797281	0.757675388931321	0.970462989411807
GO:0001664	G protein-coupled receptor binding	32/2227	297/18639	0.107744107744108	0.901770284796778	0.760527121395938	0.970462989411807
GO:0019783	ubiquitin-like protein peptidase activity	13/2227	127/18639	0.102362204724409	0.856726149015836	0.7636098078504	0.970462989411807
GO:0030971	receptor tyrosine kinase binding	8/2227	81/18639	0.0987654320987654	0.826622761063713	0.766750490151158	0.970462989411807
GO:0004620	phospholipase activity	11/2227	109/18639	0.100917431192661	0.844634036820835	0.767516554038648	0.970462989411807
GO:0022804	active transmembrane transporter activity	50/2227	457/18639	0.109409190371991	0.915706286189288	0.769511871537911	0.970462989411807
GO:0015293	symporter activity	15/2227	146/18639	0.102739726027397	0.859885834496927	0.77043114807861	0.970462989411807
GO:0016251	RNA polymerase II general transcription initiation factor activity	5/2227	53/18639	0.0943396226415094	0.789580703374537	0.774944983739521	0.970462989411807
GO:0034212	protein N-acetyltransferase activity	5/2227	53/18639	0.0943396226415094	0.789580703374537	0.774944983739521	0.970462989411807
GO:0140375	immune receptor activity	16/2227	156/18639	0.102564102564103	0.858415944181548	0.778128637585981	0.970462989411807
GO:0005507	copper ion binding	6/2227	63/18639	0.0952380952380952	0.797100519597152	0.779327387517345	0.970462989411807
GO:0000295	adenine nucleotide transmembrane transporter activity	2/2227	23/18639	0.0869565217391304	0.72778743093653	0.779386285351974	0.970462989411807
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	2/2227	23/18639	0.0869565217391304	0.72778743093653	0.779386285351974	0.970462989411807
GO:0005212	structural constituent of eye lens	2/2227	23/18639	0.0869565217391304	0.72778743093653	0.779386285351974	0.970462989411807
GO:0005283	amino acid:sodium symporter activity	2/2227	23/18639	0.0869565217391304	0.72778743093653	0.779386285351974	0.970462989411807
GO:0043274	phospholipase binding	2/2227	23/18639	0.0869565217391304	0.72778743093653	0.779386285351974	0.970462989411807
GO:0004032	aldose reductase (NADPH) activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0004300	enoyl-CoA hydratase activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0005025	transforming growth factor beta receptor activity, type I	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0005026	transforming growth factor beta receptor activity, type II	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0005049	nuclear export signal receptor activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0005078	MAP-kinase scaffold activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0005095	GTPase inhibitor activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0005247	voltage-gated chloride channel activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0015132	prostaglandin transmembrane transporter activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0015166	polyol transmembrane transporter activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0015269	calcium-activated potassium channel activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0015368	calcium:monoatomic cation antiporter activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0016361	activin receptor activity, type I	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0016362	activin receptor activity, type II	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0017002	activin receptor activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0035251	UDP-glucosyltransferase activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0070410	co-SMAD binding	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0097371	MDM2/MDM4 family protein binding	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0140900	chloride:bicarbonate antiporter activity	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:1990459	transferrin receptor binding	1/2227	12/18639	0.0833333333333333	0.697462954647508	0.782900893649118	0.970462989411807
GO:0016790	thiolester hydrolase activity	4/2227	44/18639	0.0909090909090909	0.760868677797281	0.787504085625461	0.972002356793115
GO:0008376	acetylgalactosaminyltransferase activity	3/2227	34/18639	0.0882352941176471	0.738490187273832	0.78954383517464	0.972002356793115
GO:0090482	vitamin transmembrane transporter activity	3/2227	34/18639	0.0882352941176471	0.738490187273832	0.78954383517464	0.972002356793115
GO:0030165	PDZ domain binding	8/2227	83/18639	0.0963855421686747	0.80670414031519	0.789848150060797	0.972002356793115
GO:0016298	lipase activity	13/2227	130/18639	0.1	0.836955545577009	0.791637657111935	0.972002356793115
GO:0008509	monoatomic anion transmembrane transporter activity	15/2227	149/18639	0.100671140939597	0.842572696889607	0.79626098441808	0.972002356793115
GO:0004806	triacylglycerol lipase activity	2/2227	24/18639	0.0833333333333333	0.697462954647508	0.799371185863536	0.972002356793115
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/2227	24/18639	0.0833333333333333	0.697462954647508	0.799371185863536	0.972002356793115
GO:0030552	cAMP binding	2/2227	24/18639	0.0833333333333333	0.697462954647508	0.799371185863536	0.972002356793115
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/2227	24/18639	0.0833333333333333	0.697462954647508	0.799371185863536	0.972002356793115
GO:0016247	channel regulator activity	17/2227	168/18639	0.101190476190476	0.846919302071974	0.80121001836399	0.972002356793115
GO:0005343	organic acid:sodium symporter activity	3/2227	35/18639	0.0857142857142857	0.717390467637437	0.805861346101803	0.972002356793115
GO:0016229	steroid dehydrogenase activity	3/2227	35/18639	0.0857142857142857	0.717390467637437	0.805861346101803	0.972002356793115
GO:0043015	gamma-tubulin binding	3/2227	35/18639	0.0857142857142857	0.717390467637437	0.805861346101803	0.972002356793115
GO:0004465	lipoprotein lipase activity	1/2227	13/18639	0.0769230769230769	0.643811958136161	0.808856748582463	0.972002356793115
GO:0004535	poly(A)-specific ribonuclease activity	1/2227	13/18639	0.0769230769230769	0.643811958136161	0.808856748582463	0.972002356793115
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/2227	13/18639	0.0769230769230769	0.643811958136161	0.808856748582463	0.972002356793115
GO:0017154	semaphorin receptor activity	1/2227	13/18639	0.0769230769230769	0.643811958136161	0.808856748582463	0.972002356793115
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/2227	13/18639	0.0769230769230769	0.643811958136161	0.808856748582463	0.972002356793115
GO:0046975	histone H3K36 methyltransferase activity	1/2227	13/18639	0.0769230769230769	0.643811958136161	0.808856748582463	0.972002356793115
GO:0051011	microtubule minus-end binding	1/2227	13/18639	0.0769230769230769	0.643811958136161	0.808856748582463	0.972002356793115
GO:0070123	transforming growth factor beta receptor activity, type III	1/2227	13/18639	0.0769230769230769	0.643811958136161	0.808856748582463	0.972002356793115
GO:0071714	icosanoid transmembrane transporter activity	1/2227	13/18639	0.0769230769230769	0.643811958136161	0.808856748582463	0.972002356793115
GO:0071837	HMG box domain binding	1/2227	13/18639	0.0769230769230769	0.643811958136161	0.808856748582463	0.972002356793115
GO:1901338	catecholamine binding	1/2227	13/18639	0.0769230769230769	0.643811958136161	0.808856748582463	0.972002356793115
GO:0099106	ion channel regulator activity	16/2227	160/18639	0.1	0.836955545577009	0.810387078783832	0.972002356793115
GO:0030170	pyridoxal phosphate binding	5/2227	56/18639	0.0892857142857143	0.74728173712233	0.814846307523276	0.972002356793115
GO:0141108	transporter regulator activity	17/2227	170/18639	0.1	0.836955545577009	0.816139684210811	0.972002356793115
GO:0003707	nuclear steroid receptor activity	2/2227	25/18639	0.08	0.669564436461608	0.817732396353505	0.972002356793115
GO:0008483	transaminase activity	2/2227	25/18639	0.08	0.669564436461608	0.817732396353505	0.972002356793115
GO:0015645	fatty acid ligase activity	2/2227	25/18639	0.08	0.669564436461608	0.817732396353505	0.972002356793115
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/2227	25/18639	0.08	0.669564436461608	0.817732396353505	0.972002356793115
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	2/2227	25/18639	0.08	0.669564436461608	0.817732396353505	0.972002356793115
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/2227	25/18639	0.08	0.669564436461608	0.817732396353505	0.972002356793115
GO:0120515	fatty acid-CoA ligase activity	2/2227	25/18639	0.08	0.669564436461608	0.817732396353505	0.972002356793115
GO:0003730	mRNA 3'-UTR binding	27/2227	262/18639	0.103053435114504	0.862511440098445	0.820802067327782	0.972002356793115
GO:0008083	growth factor activity	16/2227	162/18639	0.0987654320987654	0.826622761063713	0.82518683849003	0.972002356793115
GO:0070279	vitamin B6 binding	5/2227	57/18639	0.087719298245614	0.734171531207903	0.826815587967678	0.972002356793115
GO:0016500	protein-hormone receptor activity	6/2227	67/18639	0.0895522388059701	0.749512428874934	0.826967108311799	0.972002356793115
GO:0008013	beta-catenin binding	10/2227	106/18639	0.0943396226415094	0.789580703374537	0.828496607006279	0.972002356793115
GO:0061749	forked DNA-dependent helicase activity	4/2227	47/18639	0.0851063829787234	0.712302591980434	0.828977481325379	0.972002356793115
GO:0140359	ABC-type transporter activity	4/2227	47/18639	0.0851063829787234	0.712302591980434	0.828977481325379	0.972002356793115
GO:0008201	heparin binding	17/2227	172/18639	0.0988372093023256	0.82722350434937	0.830239481573773	0.972002356793115
GO:0005313	L-glutamate transmembrane transporter activity	1/2227	14/18639	0.0714285714285714	0.597825389697864	0.831710609900344	0.972002356793115
GO:0008195	phosphatidate phosphatase activity	1/2227	14/18639	0.0714285714285714	0.597825389697864	0.831710609900344	0.972002356793115
GO:0008392	arachidonate epoxygenase activity	1/2227	14/18639	0.0714285714285714	0.597825389697864	0.831710609900344	0.972002356793115
GO:0015926	glucosidase activity	1/2227	14/18639	0.0714285714285714	0.597825389697864	0.831710609900344	0.972002356793115
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/2227	14/18639	0.0714285714285714	0.597825389697864	0.831710609900344	0.972002356793115
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/2227	14/18639	0.0714285714285714	0.597825389697864	0.831710609900344	0.972002356793115
GO:0031404	chloride ion binding	1/2227	14/18639	0.0714285714285714	0.597825389697864	0.831710609900344	0.972002356793115
GO:0042813	Wnt receptor activity	1/2227	14/18639	0.0714285714285714	0.597825389697864	0.831710609900344	0.972002356793115
GO:0061665	SUMO ligase activity	1/2227	14/18639	0.0714285714285714	0.597825389697864	0.831710609900344	0.972002356793115
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/2227	14/18639	0.0714285714285714	0.597825389697864	0.831710609900344	0.972002356793115
GO:0098821	BMP receptor activity	1/2227	14/18639	0.0714285714285714	0.597825389697864	0.831710609900344	0.972002356793115
GO:0015216	purine nucleotide transmembrane transporter activity	2/2227	26/18639	0.0769230769230769	0.643811958136161	0.834572424844611	0.972002356793115
GO:0019865	immunoglobulin binding	2/2227	26/18639	0.0769230769230769	0.643811958136161	0.834572424844611	0.972002356793115
GO:0050750	low-density lipoprotein particle receptor binding	2/2227	26/18639	0.0769230769230769	0.643811958136161	0.834572424844611	0.972002356793115
GO:0051139	metal cation:proton antiporter activity	2/2227	26/18639	0.0769230769230769	0.643811958136161	0.834572424844611	0.972002356793115
GO:0097602	cullin family protein binding	2/2227	26/18639	0.0769230769230769	0.643811958136161	0.834572424844611	0.972002356793115
GO:0030551	cyclic nucleotide binding	3/2227	37/18639	0.0810810810810811	0.6786126045219	0.835303987595432	0.972002356793115
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	6/2227	68/18639	0.0882352941176471	0.738490187273832	0.837500815196982	0.972002356793115
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	5/2227	58/18639	0.0862068965517241	0.721513401359491	0.838148926784116	0.972002356793115
GO:0009378	four-way junction helicase activity	4/2227	48/18639	0.0833333333333333	0.697462954647508	0.841215135948168	0.972002356793115
GO:0032266	phosphatidylinositol-3-phosphate binding	4/2227	48/18639	0.0833333333333333	0.697462954647508	0.841215135948168	0.972002356793115
GO:0036121	double-stranded DNA helicase activity	4/2227	48/18639	0.0833333333333333	0.697462954647508	0.841215135948168	0.972002356793115
GO:0015103	inorganic anion transmembrane transporter activity	16/2227	165/18639	0.096969696969697	0.8115932563171	0.845761403157822	0.972002356793115
GO:0005501	retinoid binding	3/2227	38/18639	0.0789473684210526	0.660754378087113	0.848525418821656	0.972002356793115
GO:0019840	isoprenoid binding	3/2227	38/18639	0.0789473684210526	0.660754378087113	0.848525418821656	0.972002356793115
GO:0004879	nuclear receptor activity	5/2227	59/18639	0.0847457627118644	0.709284360658483	0.848866088283707	0.972002356793115
GO:0004364	glutathione transferase activity	2/2227	27/18639	0.0740740740740741	0.619967070797785	0.84999247332625	0.972002356793115
GO:0008395	steroid hydroxylase activity	2/2227	27/18639	0.0740740740740741	0.619967070797785	0.84999247332625	0.972002356793115
GO:0016405	CoA-ligase activity	2/2227	27/18639	0.0740740740740741	0.619967070797785	0.84999247332625	0.972002356793115
GO:0035255	ionotropic glutamate receptor binding	2/2227	27/18639	0.0740740740740741	0.619967070797785	0.84999247332625	0.972002356793115
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	51/2227	484/18639	0.105371900826446	0.881915967446849	0.851428896508963	0.972002356793115
GO:0004129	cytochrome-c oxidase activity	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0004467	long-chain fatty acid-CoA ligase activity	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0004559	alpha-mannosidase activity	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0004953	icosanoid receptor activity	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0008242	omega peptidase activity	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0010181	FMN binding	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0015116	sulfate transmembrane transporter activity	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0015929	hexosaminidase activity	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0016846	carbon-sulfur lyase activity	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0033130	acetylcholine receptor binding	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0045504	dynein heavy chain binding	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0048531	beta-1,3-galactosyltransferase activity	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0050700	CARD domain binding	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/2227	15/18639	0.0666666666666667	0.557970363718006	0.85183305133669	0.972002356793115
GO:0004175	endopeptidase activity	42/2227	405/18639	0.103703703703704	0.867953899116899	0.857801551825994	0.977939681742748
GO:0016798	hydrolase activity, acting on glycosyl bonds	12/2227	130/18639	0.0923076923076923	0.772574349763393	0.865136648055347	0.982568880520819
GO:0005024	transforming growth factor beta receptor activity	1/2227	16/18639	0.0625	0.523097215985631	0.869550394263729	0.982568880520819
GO:0008391	arachidonate monooxygenase activity	1/2227	16/18639	0.0625	0.523097215985631	0.869550394263729	0.982568880520819
GO:0015923	mannosidase activity	1/2227	16/18639	0.0625	0.523097215985631	0.869550394263729	0.982568880520819
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/2227	16/18639	0.0625	0.523097215985631	0.869550394263729	0.982568880520819
GO:0016722	oxidoreductase activity, acting on metal ions	1/2227	16/18639	0.0625	0.523097215985631	0.869550394263729	0.982568880520819
GO:0022841	potassium ion leak channel activity	1/2227	16/18639	0.0625	0.523097215985631	0.869550394263729	0.982568880520819
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/2227	16/18639	0.0625	0.523097215985631	0.869550394263729	0.982568880520819
GO:0034450	ubiquitin-ubiquitin ligase activity	1/2227	16/18639	0.0625	0.523097215985631	0.869550394263729	0.982568880520819
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/2227	16/18639	0.0625	0.523097215985631	0.869550394263729	0.982568880520819
GO:0005518	collagen binding	6/2227	72/18639	0.0833333333333333	0.697462954647508	0.874551843019223	0.982816409434989
GO:0001216	DNA-binding transcription activator activity	51/2227	491/18639	0.103869653767821	0.869342827381415	0.876506838850109	0.982816409434989
GO:0004181	metallocarboxypeptidase activity	2/2227	29/18639	0.0689655172413793	0.577210721087593	0.876964295837037	0.982816409434989
GO:0005416	amino acid:monoatomic cation symporter activity	2/2227	29/18639	0.0689655172413793	0.577210721087593	0.876964295837037	0.982816409434989
GO:0005253	monoatomic anion channel activity	9/2227	103/18639	0.087378640776699	0.731320379630397	0.880498486537067	0.982816409434989
GO:0005254	chloride channel activity	7/2227	83/18639	0.0843373493975904	0.705866122775791	0.880894971244539	0.982816409434989
GO:0004812	aminoacyl-tRNA ligase activity	3/2227	41/18639	0.0731707317073171	0.612406496763665	0.882783427207155	0.982816409434989
GO:0008137	NADH dehydrogenase (ubiquinone) activity	3/2227	41/18639	0.0731707317073171	0.612406496763665	0.882783427207155	0.982816409434989
GO:0008227	G protein-coupled amine receptor activity	3/2227	41/18639	0.0731707317073171	0.612406496763665	0.882783427207155	0.982816409434989
GO:0016875	ligase activity, forming carbon-oxygen bonds	3/2227	41/18639	0.0731707317073171	0.612406496763665	0.882783427207155	0.982816409434989
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	4/2227	52/18639	0.0769230769230769	0.643811958136161	0.883024202512511	0.982816409434989
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/2227	17/18639	0.0588235294117647	0.492326791515888	0.885149990031043	0.982816409434989
GO:0008484	sulfuric ester hydrolase activity	1/2227	17/18639	0.0588235294117647	0.492326791515888	0.885149990031043	0.982816409434989
GO:0009881	photoreceptor activity	1/2227	17/18639	0.0588235294117647	0.492326791515888	0.885149990031043	0.982816409434989
GO:0015278	intracellularly gated calcium channel activity	1/2227	17/18639	0.0588235294117647	0.492326791515888	0.885149990031043	0.982816409434989
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/2227	17/18639	0.0588235294117647	0.492326791515888	0.885149990031043	0.982816409434989
GO:0016805	dipeptidase activity	1/2227	17/18639	0.0588235294117647	0.492326791515888	0.885149990031043	0.982816409434989
GO:0030548	acetylcholine receptor regulator activity	1/2227	17/18639	0.0588235294117647	0.492326791515888	0.885149990031043	0.982816409434989
GO:0045125	bioactive lipid receptor activity	1/2227	17/18639	0.0588235294117647	0.492326791515888	0.885149990031043	0.982816409434989
GO:0070492	oligosaccharide binding	1/2227	17/18639	0.0588235294117647	0.492326791515888	0.885149990031043	0.982816409434989
GO:0001965	G-protein alpha-subunit binding	2/2227	30/18639	0.0666666666666667	0.557970363718006	0.88870299878904	0.985049811320376
GO:0015215	nucleotide transmembrane transporter activity	2/2227	30/18639	0.0666666666666667	0.557970363718006	0.88870299878904	0.985049811320376
GO:0101005	deubiquitinase activity	10/2227	115/18639	0.0869565217391304	0.72778743093653	0.893650659730655	0.986635335183838
GO:0004867	serine-type endopeptidase inhibitor activity	8/2227	95/18639	0.0842105263157895	0.704804669959587	0.893862315507359	0.986635335183838
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/2227	18/18639	0.0555555555555556	0.464975303098339	0.898884872009395	0.986635335183838
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/2227	18/18639	0.0555555555555556	0.464975303098339	0.898884872009395	0.986635335183838
GO:0032393	MHC class I receptor activity	1/2227	18/18639	0.0555555555555556	0.464975303098339	0.898884872009395	0.986635335183838
GO:0034185	apolipoprotein binding	1/2227	18/18639	0.0555555555555556	0.464975303098339	0.898884872009395	0.986635335183838
GO:0035615	clathrin adaptor activity	1/2227	18/18639	0.0555555555555556	0.464975303098339	0.898884872009395	0.986635335183838
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/2227	18/18639	0.0555555555555556	0.464975303098339	0.898884872009395	0.986635335183838
GO:0099602	neurotransmitter receptor regulator activity	1/2227	18/18639	0.0555555555555556	0.464975303098339	0.898884872009395	0.986635335183838
GO:0047499	calcium-independent phospholipase A2 activity	2/2227	31/18639	0.0645161290322581	0.539971319727103	0.899394538987366	0.986635335183838
GO:0070325	lipoprotein particle receptor binding	2/2227	31/18639	0.0645161290322581	0.539971319727103	0.899394538987366	0.986635335183838
GO:0004497	monooxygenase activity	9/2227	106/18639	0.0849056603773585	0.710622633037083	0.899482184992749	0.986635335183838
GO:0015078	proton transmembrane transporter activity	17/2227	185/18639	0.0918918918918919	0.769094285124819	0.902920084394285	0.986635335183838
GO:1990782	protein tyrosine kinase binding	10/2227	117/18639	0.0854700854700855	0.71534662015129	0.904942332462096	0.986635335183838
GO:0005125	cytokine activity	22/2227	234/18639	0.094017094017094	0.786881282166419	0.908452671654286	0.986635335183838
GO:0042910	xenobiotic transmembrane transporter activity	2/2227	32/18639	0.0625	0.523097215985631	0.909121438878353	0.986635335183838
GO:0047498	calcium-dependent phospholipase A2 activity	2/2227	32/18639	0.0625	0.523097215985631	0.909121438878353	0.986635335183838
GO:0003954	NADH dehydrogenase activity	3/2227	44/18639	0.0681818181818182	0.570651508347961	0.909955605795102	0.986635335183838
GO:0030547	signaling receptor inhibitor activity	3/2227	44/18639	0.0681818181818182	0.570651508347961	0.909955605795102	0.986635335183838
GO:0003756	protein disulfide isomerase activity	1/2227	19/18639	0.0526315789473684	0.440502918724742	0.910977852517159	0.986635335183838
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/2227	19/18639	0.0526315789473684	0.440502918724742	0.910977852517159	0.986635335183838
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/2227	19/18639	0.0526315789473684	0.440502918724742	0.910977852517159	0.986635335183838
GO:0022840	leak channel activity	1/2227	19/18639	0.0526315789473684	0.440502918724742	0.910977852517159	0.986635335183838
GO:0022842	narrow pore channel activity	1/2227	19/18639	0.0526315789473684	0.440502918724742	0.910977852517159	0.986635335183838
GO:0042834	peptidoglycan binding	1/2227	19/18639	0.0526315789473684	0.440502918724742	0.910977852517159	0.986635335183838
GO:0050145	nucleoside monophosphate kinase activity	1/2227	19/18639	0.0526315789473684	0.440502918724742	0.910977852517159	0.986635335183838
GO:0070003	threonine-type peptidase activity	1/2227	19/18639	0.0526315789473684	0.440502918724742	0.910977852517159	0.986635335183838
GO:0019239	deaminase activity	2/2227	33/18639	0.0606060606060606	0.507245785198188	0.917961459835524	0.992516705304399
GO:0030296	protein tyrosine kinase activator activity	2/2227	33/18639	0.0606060606060606	0.507245785198188	0.917961459835524	0.992516705304399
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	11/2227	130/18639	0.0846153846153846	0.708193153949777	0.919633776279354	0.993484333123427
GO:0001614	purinergic nucleotide receptor activity	1/2227	20/18639	0.05	0.418477772788505	0.92162513084392	0.993955204403822
GO:0016502	nucleotide receptor activity	1/2227	20/18639	0.05	0.418477772788505	0.92162513084392	0.993955204403822
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	3/2227	46/18639	0.0652173913043478	0.545840573202397	0.924750756322161	0.996138134208407
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/2227	34/18639	0.0588235294117647	0.492326791515888	0.925987561376829	0.996138134208407
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/2227	34/18639	0.0588235294117647	0.492326791515888	0.925987561376829	0.996138134208407
GO:0001846	opsonin binding	1/2227	21/18639	0.0476190476190476	0.398550259798576	0.930999470690882	0.998168895589721
GO:0036122	BMP binding	1/2227	21/18639	0.0476190476190476	0.398550259798576	0.930999470690882	0.998168895589721
GO:0051428	peptide hormone receptor binding	1/2227	21/18639	0.0476190476190476	0.398550259798576	0.930999470690882	0.998168895589721
GO:0061891	calcium ion sensor activity	1/2227	21/18639	0.0476190476190476	0.398550259798576	0.930999470690882	0.998168895589721
GO:0004623	phospholipase A2 activity	2/2227	35/18639	0.0571428571428571	0.478260311758291	0.933267938060164	0.999134875008327
GO:0070888	E-box binding	4/2227	59/18639	0.0677966101694915	0.567427488526786	0.93346403815332	0.999134875008327
GO:0005539	glycosaminoglycan binding	22/2227	242/18639	0.0909090909090909	0.760868677797281	0.934943693954786	0.999881205752482
GO:0038187	pattern recognition receptor activity	3/2227	48/18639	0.0625	0.523097215985631	0.937285126771102	0.999999999999216
GO:0005243	gap junction channel activity	1/2227	22/18639	0.0454545454545455	0.380434338898641	0.939252998393718	0.999999999999216
GO:0016881	acid-amino acid ligase activity	1/2227	22/18639	0.0454545454545455	0.380434338898641	0.939252998393718	0.999999999999216
GO:0016836	hydro-lyase activity	4/2227	61/18639	0.0655737704918033	0.548823308575088	0.943713474813594	0.999999999999216
GO:0003887	DNA-directed DNA polymerase activity	1/2227	23/18639	0.0434782608695652	0.363893715468265	0.946519667168343	0.999999999999216
GO:0008171	O-methyltransferase activity	1/2227	23/18639	0.0434782608695652	0.363893715468265	0.946519667168343	0.999999999999216
GO:0016849	phosphorus-oxygen lyase activity	1/2227	23/18639	0.0434782608695652	0.363893715468265	0.946519667168343	0.999999999999216
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/2227	23/18639	0.0434782608695652	0.363893715468265	0.946519667168343	0.999999999999216
GO:0048020	CCR chemokine receptor binding	3/2227	50/18639	0.06	0.502173327346206	0.947863702404302	0.999999999999216
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/2227	24/18639	0.0416666666666667	0.348731477323754	0.952917427225074	0.999999999999216
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/2227	24/18639	0.0416666666666667	0.348731477323754	0.952917427225074	0.999999999999216
GO:0005540	hyaluronic acid binding	1/2227	24/18639	0.0416666666666667	0.348731477323754	0.952917427225074	0.999999999999216
GO:0030215	semaphorin receptor binding	1/2227	24/18639	0.0416666666666667	0.348731477323754	0.952917427225074	0.999999999999216
GO:0050431	transforming growth factor beta binding	1/2227	24/18639	0.0416666666666667	0.348731477323754	0.952917427225074	0.999999999999216
GO:0140612	DNA damage sensor activity	1/2227	24/18639	0.0416666666666667	0.348731477323754	0.952917427225074	0.999999999999216
GO:0004843	cysteine-type deubiquitinase activity	8/2227	108/18639	0.0740740740740741	0.619967070797785	0.954033931858617	0.999999999999216
GO:0008081	phosphoric diester hydrolase activity	6/2227	87/18639	0.0689655172413793	0.577210721087593	0.95673776047873	0.999999999999216
GO:0001848	complement binding	1/2227	25/18639	0.04	0.334782218230804	0.958550136844723	0.999999999999216
GO:0005251	delayed rectifier potassium channel activity	1/2227	25/18639	0.04	0.334782218230804	0.958550136844723	0.999999999999216
GO:0071855	neuropeptide receptor binding	2/2227	40/18639	0.05	0.418477772788505	0.960552741637496	0.999999999999216
GO:0017046	peptide hormone binding	3/2227	53/18639	0.0566037735849057	0.473748422024722	0.960655183819973	0.999999999999216
GO:0005179	hormone activity	10/2227	132/18639	0.0757575757575758	0.634057231497734	0.961541745281433	0.999999999999216
GO:0008236	serine-type peptidase activity	16/2227	194/18639	0.0824742268041237	0.690272614908874	0.96193445903184	0.999999999999216
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/2227	26/18639	0.0384615384615385	0.321905979068081	0.963509245324727	0.999999999999216
GO:0005227	calcium-activated cation channel activity	1/2227	26/18639	0.0384615384615385	0.321905979068081	0.963509245324727	0.999999999999216
GO:0070412	R-SMAD binding	1/2227	26/18639	0.0384615384615385	0.321905979068081	0.963509245324727	0.999999999999216
GO:0017080	sodium channel regulator activity	2/2227	41/18639	0.0487804878048781	0.408270997842444	0.964540911608282	0.999999999999216
GO:0140828	metal cation:monoatomic cation antiporter activity	2/2227	41/18639	0.0487804878048781	0.408270997842444	0.964540911608282	0.999999999999216
GO:0004252	serine-type endopeptidase activity	14/2227	176/18639	0.0795454545454545	0.665760093072621	0.966623547034739	0.999999999999216
GO:0005104	fibroblast growth factor receptor binding	1/2227	27/18639	0.037037037037037	0.309983535398892	0.967875275016976	0.999999999999216
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	6/2227	91/18639	0.0659340659340659	0.551838821259567	0.968126751215914	0.999999999999216
GO:0017171	serine hydrolase activity	16/2227	198/18639	0.0808080808080808	0.676327713597583	0.969374506249767	0.999999999999216
GO:0005242	inward rectifier potassium channel activity	1/2227	28/18639	0.0357142857142857	0.298912694848932	0.971719126432041	0.999999999999216
GO:0045499	chemorepellent activity	1/2227	28/18639	0.0357142857142857	0.298912694848932	0.971719126432041	0.999999999999216
GO:0030020	extracellular matrix structural constituent conferring tensile strength	2/2227	44/18639	0.0454545454545455	0.380434338898641	0.974310464116039	0.999999999999216
GO:0099604	ligand-gated calcium channel activity	1/2227	29/18639	0.0344827586206897	0.288605360543796	0.97510322752472	0.999999999999216
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/2227	30/18639	0.0333333333333333	0.278985181859003	0.978082545756985	0.999999999999216
GO:0022839	monoatomic ion-gated channel activity	1/2227	30/18639	0.0333333333333333	0.278985181859003	0.978082545756985	0.999999999999216
GO:0048019	receptor antagonist activity	1/2227	30/18639	0.0333333333333333	0.278985181859003	0.978082545756985	0.999999999999216
GO:0005184	neuropeptide hormone activity	1/2227	31/18639	0.032258064516129	0.269985659863551	0.980705479315972	0.999999999999216
GO:0017147	Wnt-protein binding	1/2227	31/18639	0.032258064516129	0.269985659863551	0.980705479315972	0.999999999999216
GO:0099095	ligand-gated monoatomic anion channel activity	2/2227	47/18639	0.0425531914893617	0.356151295990217	0.981453035192421	0.999999999999216
GO:0160041	neuropeptide activity	1/2227	32/18639	0.03125	0.261548607992815	0.983014641910734	0.999999999999216
GO:0042923	neuropeptide binding	1/2227	33/18639	0.0303030303030303	0.253622892599094	0.985047553850585	0.999999999999216
GO:0015020	glucuronosyltransferase activity	1/2227	34/18639	0.0294117647058824	0.246163395757944	0.986837250592213	0.999999999999216
GO:0015370	solute:sodium symporter activity	4/2227	79/18639	0.0506329113924051	0.423774959785828	0.988661298694607	0.999999999999216
GO:0004190	aspartic-type endopeptidase activity	1/2227	36/18639	0.0277777777777778	0.232487651549169	0.98979986725118	0.999999999999216
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/2227	36/18639	0.0277777777777778	0.232487651549169	0.98979986725118	0.999999999999216
GO:0030280	structural constituent of skin epidermis	1/2227	37/18639	0.027027027027027	0.2262042015073	0.991020944261965	0.999999999999216
GO:0070001	aspartic-type peptidase activity	1/2227	37/18639	0.027027027027027	0.2262042015073	0.991020944261965	0.999999999999216
GO:0005201	extracellular matrix structural constituent	11/2227	168/18639	0.0654761904761905	0.548006607223042	0.992935475070536	0.999999999999216
GO:0098960	postsynaptic neurotransmitter receptor activity	2/2227	69/18639	0.0289855072463768	0.242595810312177	0.998427264317568	0.999999999999216
GO:0005272	sodium channel activity	1/2227	51/18639	0.0196078431372549	0.164108930505296	0.998494624163683	0.999999999999216
GO:0008146	sulfotransferase activity	1/2227	53/18639	0.0188679245283019	0.157916140674907	0.998833738009373	0.999999999999216
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/2227	53/18639	0.0188679245283019	0.157916140674907	0.998833738009373	0.999999999999216
GO:0015079	potassium ion transmembrane transporter activity	8/2227	160/18639	0.05	0.418477772788505	0.999202481210667	0.999999999999216
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/2227	56/18639	0.0178571428571429	0.149456347424466	0.99920475849825	0.999999999999216
GO:0003823	antigen binding	9/2227	174/18639	0.0517241379310345	0.432908040815695	0.999292805844004	0.999999999999216
GO:0030594	neurotransmitter receptor activity	3/2227	97/18639	0.0309278350515464	0.258852230590828	0.999574453234906	0.999999999999216
GO:0005249	voltage-gated potassium channel activity	3/2227	98/18639	0.0306122448979592	0.256210881299085	0.999618313951544	0.999999999999216
GO:0022824	transmitter-gated monoatomic ion channel activity	1/2227	63/18639	0.0158730158730159	0.132850086599525	0.999674642276059	0.999999999999216
GO:0022835	transmitter-gated channel activity	1/2227	63/18639	0.0158730158730159	0.132850086599525	0.999674642276059	0.999999999999216
GO:0015085	calcium ion transmembrane transporter activity	6/2227	147/18639	0.0408163265306122	0.341614508398779	0.999765853752564	0.999999999999216
GO:0015081	sodium ion transmembrane transporter activity	7/2227	164/18639	0.0426829268292683	0.357237123112138	0.999828089635541	0.999999999999216
GO:0016782	transferase activity, transferring sulphur-containing groups	1/2227	70/18639	0.0142857142857143	0.119565077939573	0.999866933980075	0.999999999999216
GO:0005267	potassium channel activity	4/2227	124/18639	0.032258064516129	0.269985659863551	0.999873551263361	0.999999999999216
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/2227	73/18639	0.0136986301369863	0.11465144459959	0.999909299919114	0.999999999999216
GO:0001653	peptide receptor activity	4/2227	128/18639	0.03125	0.261548607992815	0.999917077065527	0.999999999999216
GO:0046873	metal ion transmembrane transporter activity	30/2227	450/18639	0.0666666666666667	0.557970363718006	0.999937829428504	0.999999999999216
GO:0099094	ligand-gated monoatomic cation channel activity	4/2227	136/18639	0.0294117647058824	0.246163395757944	0.999964623549494	0.999999999999216
GO:0015276	ligand-gated monoatomic ion channel activity	7/2227	186/18639	0.0376344086021505	0.31498326984081	0.999978799173764	0.999999999999216
GO:0022834	ligand-gated channel activity	7/2227	188/18639	0.0372340425531915	0.31163238399144	0.999982547495709	0.999999999999216
GO:0005262	calcium channel activity	3/2227	131/18639	0.0229007633587786	0.191669208910766	0.999990350910052	0.999999999999216
GO:0005244	voltage-gated monoatomic ion channel activity	5/2227	173/18639	0.0289017341040462	0.241894666351737	0.999996248969966	0.999999999999216
GO:0030527	structural constituent of chromatin	1/2227	98/18639	0.0102040816326531	0.0854036270996948	0.999996290388343	0.999999999999216
GO:0008528	G protein-coupled peptide receptor activity	2/2227	122/18639	0.0163934426229508	0.137205827143772	0.999996965252509	0.999999999999216
GO:0022832	voltage-gated channel activity	5/2227	175/18639	0.0285714285714286	0.239130155879146	0.999996966590241	0.999999999999216
GO:0022843	voltage-gated monoatomic cation channel activity	3/2227	143/18639	0.020979020979021	0.17558507949168	0.999997550674486	0.999999999999216
GO:0022836	gated channel activity	13/2227	318/18639	0.0408805031446541	0.342151638128966	0.999999780911519	0.999999999999216
GO:0005216	monoatomic ion channel activity	22/2227	448/18639	0.0491071428571429	0.411004955417281	0.999999928209396	0.999999999999216
GO:0005261	monoatomic cation channel activity	10/2227	341/18639	0.0293255131964809	0.245441508966865	0.999999999670527	0.999999999999216
GO:0045182	translation regulator activity	8/2227	356/18639	0.0224719101123595	0.188079897882474	0.999999999997947	0.999999999999216
GO:0030371	translation repressor activity	6/2227	329/18639	0.0182370820668693	0.152636269710093	0.999999999999216	0.999999999999216