category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	31/157	238/9376	7.77862227693625	JUN/FOS/RPL3/RPL36A/NFKBIA/RPS26/RPL27A/RPS2/RPS10/RPL7A/RPS3/RPS4X/RPL9/RPS20/RPL36AL/RPL15/TNF/RPL23A/RPS18/RPLP0/RPL5/RPL13/RPS6/RPL8/EIF2AK2/ADAR/RPS9/RPL29/RPS14/RPSA/RPL6	13.8228594802147
Genetic Information Processing	Translation	hsa03010	Ribosome	26/157	222/9376	6.99420439547828	RPL3/RPL36A/RPS26/RPL27A/RPS2/RPS10/RPL7A/RPS3/RPS4X/RPL9/RPS20/RPL36AL/RPL15/RPL23A/RPS18/RPLP0/RPL5/RPL13/RPS6/RPL8/MRPL41/RPS9/RPL29/RPS14/RPSA/RPL6	11.7949509150918
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	19/157	205/9376	5.53500077675936	JUN/HLA-A/NFKBIA/VIM/HLA-F/HLA-DPB1/HLA-DPA1/GADD45B/HLA-C/TNF/TAP1/TNFAIP3/BAX/EIF2AK2/HLA-DRA/CD3D/PSMC3/CD3E/B2M	8.56721185467807
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	25/157	368/9376	4.05704790916644	MT-ATP6/MT-CYB/MT-ND1/MT-CO3/MT-CO1/MT-ND2/SRSF7/HNRNPA1/ACTG1/TUBA1B/TUBA4A/MT-ND4/TNF/NDUFB8/MT-CO2/BAX/TUBA1A/NDUFAB1/UQCRC2/UQCRH/PSMC3/RAB8A/GPX1/CHCHD10/GPX3	7.80738367813177
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	21/157	275/9376	4.56041690793283	MT-ATP6/MT-CYB/MT-ND1/MT-CO3/MT-CO1/MT-ND2/TUBA1B/TUBA4A/MT-ND4/TNF/NDUFB8/MT-CO2/CYBA/BAX/EGR1/TUBA1A/NDUFAB1/UQCRC2/UQCRH/PSMC3/PRNP	7.82017013110142
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	17/157	180/9376	5.64019815994338	HLA-A/NFKBIA/SRSF5/HLA-F/SRSF7/HLA-DPB1/HLA-DPA1/HLA-C/BST2/TNF/SRSF9/TAP1/BAX/EIF2AK2/HLA-DRA/B2M/SP100	8.20288939467414
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	21/157	308/9376	4.07180081065431	MT-ATP6/MT-CYB/MT-ND1/MT-CO3/MT-CO1/MT-ND2/TUBA1B/TUBA4A/MT-ND4/NDUFB8/POLR2E/MT-CO2/BAX/TUBA1A/NDUFAB1/UQCRC2/UQCRH/PSMC3/GPX1/GPX3/AP2S1	7.15329622718823
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	19/157	268/9376	4.23386253446145	MT-ATP6/DUSP1/MT-CYB/MT-ND1/MT-CO3/MT-CO1/MT-ND2/TUBA1B/TUBA4A/MT-ND4/UBC/NDUFB8/MT-CO2/BAX/TUBA1A/NDUFAB1/UQCRC2/UQCRH/PSMC3	7.00924108388961
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	17/157	224/9376	4.53230209281165	JUN/FOS/HLA-A/NFKBIA/HLA-F/HLA-DPB1/HLA-DPA1/HLA-C/TNF/ZFP36/BAX/EGR1/HLA-DRA/CD3D/CD3E/B2M/RAN	6.98260377678116
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	17/157	227/9376	4.47240382726788	JUN/FOS/MT-ATP6/MT-CYB/MT-ND1/MT-CO3/NFKBIA/MT-CO1/MT-ND2/MT-ND4/NDUFB8/MT-CO2/CYBA/NDUFAB1/UQCRC2/UQCRH/GRB2	6.91114329911803
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	10/157	82/9376	7.2828957588939	HLA-A/HLA-F/HLA-DPB1/HLA-DPA1/HLA-C/TNF/TAP1/HLA-DRA/B2M/PSME2	7.45691174878198
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	15/157	214/9376	4.18596345020537	JUN/FOS/HLA-A/CXCR4/NFKBIA/HLA-F/HLA-C/BST2/TNF/TAP1/BAX/APOBEC3G/CD3D/CD3E/B2M	6.15242161223454
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	12/157	138/9376	5.19302132373304	MT-ATP6/MT-CYB/MT-ND1/MT-CO3/MT-CO1/MT-ND2/MT-ND4/NDUFB8/MT-CO2/NDUFAB1/UQCRC2/UQCRH	6.47546845679541
Human Diseases	Immune disease	hsa05330	Allograft rejection	7/157	39/9376	10.7189286297567	HLA-A/HLA-F/HLA-DPB1/HLA-DPA1/HLA-C/TNF/HLA-DRA	7.93671113440766
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	16/157	248/9376	3.85288678857612	JUN/FOS/GAPDH/NFKBIA/RPS3/ACTG1/TUBA1B/TUBA4A/TNF/ARF6/ANXA2/ARPC1B/BAX/TUBA1A/DYNLL1/S100A10	5.94177386885273
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	23/157	480/9376	2.86157112526539	MT-ATP6/MT-CYB/MT-ND1/MT-CO3/MT-CO1/MT-ND2/TUBA1B/TUBA4A/MT-ND4/UBC/TNF/NDUFB8/MT-CO2/BAX/TUBA1A/NDUFAB1/UQCRC2/UQCRH/PSMC3/RAB8A/GPX1/PRNP/GPX3	5.46382049038004
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	9/157	78/9376	6.89073983341499	JUN/FOS/EEF1A1/NFKBIA/HLA-DPB1/HLA-DPA1/TNF/CYBA/HLA-DRA	6.81735531605859
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	14/157	200/9376	4.1803821656051	JUN/FOS/GAPDH/NFKBIA/RPS3/ACTG1/TUBA1B/TUBA4A/TNF/ARF6/ARPC1B/MYH9/BAX/TUBA1A	5.93281985740421
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	7/157	44/9376	9.5008685581934	HLA-A/HLA-F/HLA-DPB1/HLA-DPA1/HLA-C/TNF/HLA-DRA	7.37557411041008
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	14/157	205/9376	4.07842162498058	MT-ATP6/MT-CYB/MT-ND1/GAPDH/MT-CO3/MT-CO1/MT-ND2/MT-ND4/NDUFB8/MT-CO2/CYBA/NDUFAB1/UQCRC2/UQCRH	5.81554260682554
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	7/157	45/9376	9.2897381457891	HLA-A/HLA-F/HLA-DPB1/HLA-DPA1/HLA-C/TNF/HLA-DRA	7.2740541790589
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	15/157	235/9376	3.81189863125085	MT-ATP6/MT-CYB/MT-ND1/MT-CO3/MT-CO1/MT-ND2/ACTG1/MT-ND4/NDUFB8/MT-CO2/RPS6/NDUFAB1/UQCRC2/UQCRH/GRB2	5.69679109546215
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	12/157	155/9376	4.62346414629135	HLA-A/HLA-F/HLA-DPB1/HLA-DPA1/ACTG1/TUBA1B/HLA-C/TUBA4A/TAP1/CYBA/TUBA1A/HLA-DRA	5.93600643916702
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	12/157	157/9376	4.56456651385452	JUN/FOS/MT-CYB/MT-CO3/MT-CO1/TNF/NDUFB8/MT-CO2/BAX/NDUFAB1/UQCRC2/UQCRH	5.87771059470476
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	11/157	137/9376	4.79501603979729	JUN/FOS/NFKBIA/MCL1/GADD45B/ACTG1/TUBA1B/TUBA4A/TNF/BAX/TUBA1A	5.83922180955071
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	19/157	388/9376	2.92442051349399	MT-ATP6/MT-CYB/MT-ND1/GAPDH/MT-CO3/MT-CO1/MT-ND2/TUBA1B/TUBA4A/MT-ND4/TNF/NDUFB8/MT-CO2/TUBA1A/NDUFAB1/EIF2AK2/UQCRC2/UQCRH/PSMC3	5.05216895097191
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	7/157	67/9376	6.23937636657477	GAPDH/LDHA/ALDOA/PGAM1/PKM/PGK1/ENO1	5.61641305146627
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	8/157	93/9376	5.13718238476817	JUN/FOS/NFKBIA/HLA-DPB1/HLA-DPA1/HLA-DRA/CD3D/CD3E	5.23233477061231
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	7/157	70/9376	5.97197452229299	HLA-A/HLA-F/HLA-DPB1/HLA-DPA1/ACTG1/HLA-C/HLA-DRA	5.44866299693055
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	8/157	94/9376	5.08253150833446	JUN/FOS/JUND/NFKBIA/FOSB/TNF/TNFAIP3/CEBPB	5.19118190007371
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	8/157	95/9376	5.02903117666778	JUN/FOS/CCL3L3/HLA-DPB1/HLA-DPA1/TNF/LTB/HLA-DRA	5.15060922317802
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	6/157	54/9376	6.63552724699222	HLA-A/HLA-F/HLA-DPB1/HLA-DPA1/HLA-C/HLA-DRA	5.41964002439638
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	12/157	227/9376	3.15699093689497	HLA-A/CXCR4/NFKBIA/CCL3L3/HLA-F/HLA-C/TNF/TAP1/PTGER4/BAX/B2M/GRB2	4.29307021917125
Human Diseases	Infectious disease: viral	hsa05162	Measles	9/157	136/9376	3.95204196328213	JUN/FOS/NFKBIA/TNFAIP3/BAX/EIF2AK2/ADAR/CD3D/CD3E	4.52532267990421
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	8/157	109/9376	4.38310056682055	JUN/FOS/NFKBIA/HLA-DPB1/HLA-DPA1/HLA-DRA/CD3D/CD3E	4.63609292494684
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	9/157	142/9376	3.78505427469274	JUN/FOS/JUNB/JUND/NFKBIA/FOSB/TNF/CYBA/GRB2	4.3639167505111
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	12/157	250/9376	2.86654777070064	HLA-A/CXCR4/HLA-F/HLA-C/ARF6/CHMP4A/SMAP2/ARPC1B/ACAP1/RAB8A/CHMP1B/AP2S1	3.90357419484312
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	6/157	75/9376	4.7775796178344	GAPDH/ALDOA/PGAM1/PKM/PGK1/ENO1	4.28620553616306
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	10/157	196/9376	3.0469257766801	JUN/FOS/HLA-A/NFKBIA/HLA-F/HLA-C/UBC/ZFP36/BAX/EIF2AK2	3.77922150349271
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	7/157	103/9376	4.05862346175252	JUN/FOS/NFKBIA/CCL3L3/TNF/CD3D/CD3E	4.07312796912878
Human Diseases	Immune disease	hsa05310	Asthma	4/157	32/9376	7.46496815286624	HLA-DPB1/HLA-DPA1/TNF/HLA-DRA	4.78044714777369
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	9/157	170/9376	3.1616335706257	JUN/ACTG1/TUBA1B/TUBA4A/RAP1A/ARPC1B/MYH9/TUBA1A/RAB8A	3.71162942230133
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	10/157	205/9376	2.91315830355756	JUN/HLA-A/NFKBIA/HLA-F/HLA-C/PKM/BAX/EIF2AK2/SP100/GRB2	3.61420720854351
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	9/157	173/9376	3.10680755495011	NFKBIA/HLA-DPB1/HLA-DPA1/ACTG1/TNF/BAX/EIF2AK2/HLA-DRA/ADAR	3.64986469165506
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	6/157	87/9376	4.11860311882275	MT-CYB/MT-CO3/MT-CO1/MT-CO2/UQCRC2/UQCRH	3.81354443113802
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	7/157	119/9376	3.51292618958411	JUN/FOS/JUNB/NFKBIA/TNF/TNFAIP3/CEBPB	3.60007574461492
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	7/157	122/9376	3.4265427586927	JUN/FOS/NFKBIA/TNF/CD3D/CD3E/GRB2	3.52043778137614
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	5/157	66/9376	4.52422312294924	JUN/HLA-DPB1/HLA-DPA1/TNF/HLA-DRA	3.74933357139188
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	6/157	100/9376	3.5831847133758	HLA-DPB1/HLA-DPA1/TNF/HLA-DRA/CD3D/CD3E	3.38897721451349
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	4/157	46/9376	5.19302132373304	PSMB9/PSMB8/PSMC3/PSME2	3.72013518526188
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	5/157	73/9376	4.09039350841986	CXCR4/BST2/CHMP4A/APOBEC3G/RAN	3.45905334245866
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	7/157	138/9376	3.02926243884427	JUN/FOS/NFKBIA/ACTG1/TNF/ARF6/ARPC1B	3.13387982048155
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	4/157	50/9376	4.7775796178344	CXCR4/HLA-DPB1/HLA-DPA1/HLA-DRA	3.49497827109281
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	7/157	142/9376	2.9439311025388	JUN/FOS/DUSP1/ACTG1/KLF2/TNF/CYBA	3.04595625919874
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	6/157	110/9376	3.25744064852345	GAPDH/LDHA/ALDOA/PGK1/RPS6/ENO1	3.10785030759939
NA	NA	hsa04517	IgSF CAM signaling	11/157	299/9376	2.19704748311782	CD48/ACTG1/TUBA1B/TUBA4A/RAP1A/ARF6/ARPC1B/MYH9/TUBA1A/DYNLL1/GRB2	2.74517073988956
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	11/157	300/9376	2.18972399150743	JUN/FOS/DUSP1/JUND/GADD45B/RAP1A/TNF/DUSP2/NR4A1/STK4/GRB2	2.73308513547295
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	6/157	116/9376	3.08895233911707	GAPDH/ALDOA/PGAM1/PKM/PGK1/ENO1	2.95423874444075
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	8/157	187/9376	2.55485541060663	JUN/NFKBIA/TNF/GBP1/GBP2/TNFAIP3/CYBA/GBP4	2.80265889275197
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	5/157	87/9376	3.43216926568563	JUN/FOS/GADD45B/BAX/GRB2	2.97414746453591
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	5/157	90/9376	3.31776362349611	JUN/FOS/NFKBIA/CD3D/CD3E	2.88316577812501
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	3/157	38/9376	4.71471672812605	TAP1/CD3D/CD3E	2.99422286134291
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	9/157	253/9376	2.12441781425442	JUN/NFKBIA/ACTG1/UBC/TNF/ARF6/FNBP1/ARPC1B/BAX	2.36598887177309
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	8/157	216/9376	2.21184241566407	JUN/FOS/NFKBIA/CCL3L3/RAP1A/TNF/CYBA/BAX	2.35135847785294
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	5/157	105/9376	2.84379739156809	NFKBIA/GADD45B/TNF/TNFAIP3/LTB	2.47935156099204
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	3/157	42/9376	4.26569608735214	SAT1/PRNP/PCBP1	2.76796165673803
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	4/157	73/9376	3.27231480673589	GADD45B/BAX/STK4/GRB2	2.54338423438411
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	5/157	109/9376	2.73943785426284	JUN/FOS/NFKBIA/CCL3L3/TNF	2.38367005953696
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	5/157	112/9376	2.66606005459509	NFKBIA/HLA-DPB1/HLA-DPA1/TNF/HLA-DRA	2.31469592427591
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	4/157	77/9376	3.10232442716519	NFKBIA/GADD45B/BAX/GRB2	2.41724422925616
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	5/157	115/9376	2.59651066186652	FOS/JUND/NR4A2/EGR1/NACA	2.24794332792604
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	4/157	83/9376	2.87806001074361	NFKBIA/POLR2E/ADAR/PCBP1	2.24266342307633
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	5/157	120/9376	2.48832271762208	JUN/NFKBIA/RAP1A/BAX/GRB2	2.14126105318332
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	6/157	160/9376	2.23949044585987	HLA-A/HLA-F/HLA-DPB1/HLA-DPA1/HLA-C/HLA-DRA	2.06359990271876
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	6/157	163/9376	2.1982728302919	JUN/FOS/NFKBIA/TNF/BAX/GRB2	2.01392148805992
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	4/157	89/9376	2.68403349316539	TUBA1B/TUBA4A/TUBA1A/GRB2	2.08305895820974
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	6/157	168/9376	2.13284804367607	TNF/CHMP4A/TNFAIP3/BAX/EIF2AK2/CHMP1B	1.93346894751411
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	4/157	91/9376	2.62504374606285	JUN/FOS/NFKBIA/GRB2	2.03277052890036
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	3/157	56/9376	3.1992720655141	EEF1A1/NFKBIA/TNF	2.15406384935675
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	5/157	133/9376	2.24510320386955	HLA-A/CD48/HLA-C/TNF/GRB2	1.88720140637358
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	3/157	59/9376	3.03659721472525	PRDX6/GPX1/GPX3	2.0477958591634
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	3/157	59/9376	3.03659721472525	GADD45B/BAX/GRB2	2.0477958591634
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	6/157	181/9376	1.97966006263856	HLA-DPB1/HLA-DPA1/TNF/CEBPB/BAX/HLA-DRA	1.73673029992355
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	4/157	99/9376	2.41291899890626	JUN/FOS/BAX/GRB2	1.84427059042285
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	4/157	99/9376	2.41291899890626	HLA-DPB1/HLA-DPA1/KRT19/HLA-DRA	1.84427059042285
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/157	101/9376	2.36513842467049	JUN/TNF/BAX/EGR1	1.80000609478358
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	5/157	143/9376	2.08810297982273	HLA-DPB1/HLA-DPA1/TNF/HLA-DRA/SSB	1.71103998064232
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	5/157	148/9376	2.01755896023412	JUN/FOS/GADD45B/BAX/GRB2	1.62828418435527
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	5/157	149/9376	2.00401829607147	MT-ND1/MT-ND2/MT-ND4/NDUFB8/NDUFAB1	1.6121225683651
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	9/157	333/9376	1.6140471681873	HLA-A/HLA-F/HLA-C/PKM/TNF/PTGER4/BAX/EIF2AK2/GRB2	1.48888495384988
Cellular Processes	Cell motility	hsa04814	Motor proteins	6/157	194/9376	1.84700242957515	ACTG1/TUBA1B/TUBA4A/MYH9/TUBA1A/DYNLL1	1.55564477180045
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	3/157	69/9376	2.59651066186652	JUN/FOS/FOSB	1.73694100738659
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	3/157	70/9376	2.55941765241128	JUN/RAP1A/GRB2	1.70892695072281
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	3/157	71/9376	2.52336951646183	LDHA/PGAM1/PKM	1.68139520047453
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	3/157	72/9376	2.48832271762208	NFKBIA/TNF/ADAR	1.65432969410827
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	5/157	156/9376	1.91409439817083	NFKBIA/TNF/BAX/EIF2AK2/GRB2	1.50238570621209
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	5/157	157/9376	1.90190271410605	HLA-A/HLA-F/GADD45B/HLA-C/ZFP36L2	1.48717189523328
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	2/157	37/9376	3.22809433637459	GADD45B/BAX	1.77205748413116
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	4/157	116/9376	2.05930155941138	CXCR4/ACTG1/RAP1A/CYBA	1.49808573908503
Human Diseases	Cancer: specific types	hsa05214	Glioma	3/157	76/9376	2.35735836406302	GADD45B/BAX/GRB2	1.55043442333923
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	3/157	78/9376	2.296913277805	BTG1/BTG2/ENO1	1.50091820025011
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/157	78/9376	2.296913277805	JUN/FOS/TNF	1.50091820025011
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	3/157	80/9376	2.23949044585987	BAX/RPS6/GRB2	1.45289315074581
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	2/157	44/9376	2.71453387376954	VAMP2/DYNLL1	1.48757407131151
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	4/157	130/9376	1.837530622244	JUN/FOS/NFKBIA/GRB2	1.2548418184572
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	4/157	133/9376	1.79608256309564	GADD45B/KLF2/STK4/GRB2	1.2066213692122
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	2/157	47/9376	2.54126575416723	LDHA/PKM	1.38230050966325
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	2/157	47/9376	2.54126575416723	PKM/TNF	1.38230050966325
NA	NA	hsa03272	Virion - Hepatitis viruses	2/157	48/9376	2.48832271762208	CHMP4A/CHMP1B	1.34901574244367
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	6/157	232/9376	1.54447616955853	CXCR4/ACTG1/TMSB4X/RGCC/ARPC1B/MYH9	1.09584294783871
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	2/157	49/9376	2.43754062134408	JUN/FOSB	1.31656023658253
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	4/157	139/9376	1.71855381936489	JUN/FOS/KRT19/GRB2	1.11376813206704
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	3/157	93/9376	1.92644339428806	JUN/EGR1/GRB2	1.17168196470728
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	3/157	93/9376	1.92644339428806	NFKBIA/GADD45B/BAX	1.17168196470728
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	5/157	193/9376	1.54714365862513	CXCR4/NFKBIA/CCL3L3/RAP1A/GRB2	1.00226205692518
Genetic Information Processing	Transcription	hsa03040	Spliceosome	6/157	243/9376	1.47456161044271	SRSF5/SRSF7/HNRNPA1/SRSF9/THOC7/PCBP1	0.978098444054597
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	3/157	99/9376	1.80968924917969	JUN/FOS/GRB2	1.05688016850196
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	3/157	100/9376	1.7915923566879	CXCR4/CCL3L3/TNF	1.03851979539337
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	1/157	17/9376	3.51292618958411	MYH9	1.35326555115647
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	3/157	105/9376	1.70627843494086	JUN/TOMM20/UBC	0.949731542182276
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	3/157	105/9376	1.70627843494086	JUN/NFKBIA/TNF	0.949731542182276
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	2/157	59/9376	2.02439814315017	UPP1/TYMP	1.03003100490864
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	3/157	107/9376	1.67438538008215	LDHA/PGAM1/PKM	0.915539637355512
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	3/157	108/9376	1.65888181174805	EEF1A1/THOC7/RAN	0.898710759651741
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	4/157	158/9376	1.51189228412481	DDIT4/TNF/RPS6/GRB2	0.846802890678645
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	2/157	63/9376	1.89586492771206	GADD45B/BAX	0.931025475898914
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/157	21/9376	2.84379739156809	CHST12	1.10381045839505
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	4/157	170/9376	1.40517047583365	GADD45B/ACTG1/BAX/GRB2	0.695697309473543
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	2/157	69/9376	1.73100710791101	TNF/GRB2	0.795307073575857
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	2/157	70/9376	1.70627843494086	NFKBIA/TNF	0.773992939170874
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	4/157	174/9376	1.37286770627425	PPP1R15A/UBXN1/SSR2/BAX	0.647861001061115
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/157	71/9376	1.68224634430789	FOS/GRB2	0.753018697344609
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/157	71/9376	1.68224634430789	JUN/NFKBIA	0.753018697344609
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	3/157	122/9376	1.46851832515401	FOS/JUNB/GRB2	0.679728229486412
Human Diseases	Cancer: specific types	hsa05218	Melanoma	2/157	73/9376	1.63615740336794	GADD45B/BAX	0.712046018235017
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/157	75/9376	1.59252653927813	GADD45B/BAX	0.672306288658297
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	2/157	75/9376	1.59252653927813	GPX1/GPX3	0.672306288658297
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	2/157	76/9376	1.57157224270868	UBC/PLIN2	0.652874954752629
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	2/157	77/9376	1.5511622135826	GADD45B/BAX	0.633724111726689
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	2/157	78/9376	1.53127551853667	ACTG1/ARPC1B	0.614845347615365
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	2/157	79/9376	1.51189228412481	VAMP2/AP2S1	0.596230612551496
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/157	30/9376	1.99065817409766	TNF	0.709194115258733
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	2/157	82/9376	1.45657915177878	UPP1/TYMP	0.54189510248177
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/157	31/9376	1.92644339428806	ALDOA	0.674223118553708
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/157	31/9376	1.92644339428806	SRP9	0.674223118553708
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	3/157	140/9376	1.27970882620564	KLF2/RPS6/EGR1	0.435132761965187
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/157	32/9376	1.86624203821656	LDHA	0.640532819800219
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/157	32/9376	1.86624203821656	BAX	0.640532819800219
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	2/157	85/9376	1.40517047583365	UPP1/TYMP	0.489676859497028
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	2/157	86/9376	1.38883128425418	JUN/GRB2	0.472711453699362
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/157	33/9376	1.80968924917969	VAMP2	0.60803100461562
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	4/157	201/9376	1.18845264125234	GADD45B/CEBPB/BAX/ID2	0.352444532599672
Genetic Information Processing	Transcription	hsa03020	RNA polymerase	1/157	34/9376	1.75646309479206	POLR2E	0.576634774155491
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	4/157	203/9376	1.17674374823507	JUN/ACTG1/RAP1A/GRB2	0.332223186963226
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	1/157	35/9376	1.70627843494086	ALDOA	0.546269356496452
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	4/157	204/9376	1.17097539652804	ACTG1/TNF/RPS6/GRB2	0.322188650087078
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	3/157	150/9376	1.1943949044586	GADD45B/BAX/GRB2	0.313196815904981
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/157	93/9376	1.28429559619204	ACTG1/RAP1A	0.359551403526275
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/157	37/9376	1.6140471681873	TNF	0.488366610978587
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/157	154/9376	1.16337166018695	JUN/FOS/ACTG1	0.266758385805155
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/157	98/9376	1.21877031067204	ARF6/ARPC1B	0.284097750001534
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	2/157	98/9376	1.21877031067204	NR4A2/NR4A1	0.284097750001534
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	3/157	157/9376	1.14114162846363	DUSP2/PTGER4/CEBPB	0.232732266812855
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	2/157	99/9376	1.20645949945313	ACTG1/TNF	0.269489746581073
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/157	41/9376	1.45657915177878	PGAM1	0.38233530348127
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/157	41/9376	1.45657915177878	TYMP	0.38233530348127
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	2/157	102/9376	1.17097539652804	RAP1A/RAB8A	0.226565467537224
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/157	103/9376	1.15960670335786	TNF/SERPINB9	0.212546112863092
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	1/157	44/9376	1.35726693688477	TAF7	0.309974063491793
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	4/157	226/9376	1.0569866411138	JUN/FOS/NFKBIA/RAP1A	0.113164520911984
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	2/157	105/9376	1.13751895662724	ACTG1/TNF	0.184921532777396
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	2/157	106/9376	1.12678764571566	NFKBIA/GRB2	0.171310333321575
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/157	45/9376	1.32710544939844	TAP1	0.287027493431542
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	3/157	169/9376	1.06011382052538	DDIT4/UBC/RAB8A	0.10290871801628
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	2/157	109/9376	1.09577514170514	NFKBIA/TNF	0.13124719412709
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	4/157	233/9376	1.02523167764687	VIM/ACTG1/MYH9/ENO1	0.0508947851248925
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/157	110/9376	1.08581354950782	TNF/ID2	0.118140721178431
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	4/157	238/9376	1.00369319702403	RAP1A/ARF6/STK4/GRB2	0.00753110903813674
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/157	50/9376	1.1943949044586	SAT1	0.179852189980698
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/157	50/9376	1.1943949044586	TNF	0.179852189980698
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/157	51/9376	1.17097539652804	ACTG1	0.159767281050691
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	2/157	117/9376	1.02085034569111	ACTG1/MORF4L1	0.0296154070063856
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/157	53/9376	1.12678764571566	AP2S1	0.120789890406868
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/157	54/9376	1.10592120783204	LDHA	0.101863551046673
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/157	125/9376	0.955515923566879	TNF/BAX	-0.0653369415687681
Organismal Systems	Immune system	hsa04611	Platelet activation	2/157	126/9376	0.947932463856031	ACTG1/RAP1A	-0.0767847527715136
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/157	61/9376	0.979012216769343	MT2A	-0.0214601925738913
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/157	63/9376	0.947932463856031	POLR2E	-0.0541110619668142
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/157	65/9376	0.918765311121999	NR4A1	-0.0857617419103795
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	2/157	138/9376	0.865503553955506	RPS6/GRB2	-0.207708815832308
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/157	67/9376	0.891339480939253	RAP1A	-0.116479961494129
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/157	68/9376	0.878231547396028	GRB2	-0.131508738907288
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/157	69/9376	0.865503553955506	PTGER4	-0.146326860234881
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/157	142/9376	0.841123172153943	UBC/UBE2S	-0.248944969082144
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/157	144/9376	0.829440905874027	ID2/GRB2	-0.269154587132803
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	2/157	144/9376	0.829440905874027	NFKBIA/TNF	-0.269154587132803
NA	NA	hsa04382	Cornified envelope formation	3/157	217/9376	0.825618597552027	S100A6/KRT19/S100A10	-0.339156043645775
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	3/157	217/9376	0.825618597552027	JUN/FOS/GRB2	-0.339156043645775
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	2/157	149/9376	0.80160731842859	ARF6/GRB2	-0.318553277974303
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/157	75/9376	0.796263269639066	BAX	-0.231168523217895
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/157	76/9376	0.785786121354341	ACTG1	-0.244684513833976
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	5/157	362/9376	0.824858359432734	MCL1/DDIT4/NR4A1/RPS6/GRB2	-0.443484533854104
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/157	155/9376	0.770577357715225	RAP1A/NR4A1	-0.375843178491777
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	4/157	298/9376	0.80160731842859	CXCR4/CCL3L3/TNF/LTB	-0.454184435603347
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	2/157	157/9376	0.76076108564242	ACTG1/ID2	-0.394487547397357
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/157	83/9376	0.719515002685903	ECH1	-0.334937883027989
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/157	86/9376	0.694415642127092	VAMP2	-0.371506182469251
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/157	86/9376	0.694415642127092	ACTG1	-0.371506182469251
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/157	168/9376	0.710949347892023	MCL1/GRB2	-0.493332237478166
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/157	90/9376	0.663552724699222	BAX	-0.418521224708589
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/157	93/9376	0.642147798096021	VAMP2	-0.452579157654731
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	4/157	323/9376	0.739563408333498	VIM/MCL1/DDIT4/GRB2	-0.621585050680689
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/157	97/9376	0.615667476525051	FOS	-0.496519116713148
NA	NA	hsa04519	Cadherin signaling	5/157	404/9376	0.739105757709529	NFKBIA/VIM/ACTG1/KRT19/ARPC1B	-0.699526387738401
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/157	99/9376	0.603229749726565	PTGER4	-0.517900675339818
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	2/157	183/9376	0.652674811179562	RAN/SBDS	-0.619194018299429
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/157	191/9376	0.625337646313402	FOSB/GRB2	-0.68266984148925
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/157	195/9376	0.612510207414666	ACTG1/CYBA	-0.713552834289714
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/157	115/9376	0.519302132373304	FOS	-0.676839553966006
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/157	115/9376	0.519302132373304	DUSP1	-0.676839553966006
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/157	122/9376	0.489506108384672	RAB8A	-0.740626546458451
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/157	122/9376	0.489506108384672	ACTG1	-0.740626546458451
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	2/157	212/9376	0.56339382285783	ACTG1/RAP1A	-0.839090536406967
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/157	133/9376	0.449020640773909	FOS	-0.835118742271936
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/157	134/9376	0.445669740469626	MYH9	-0.843396045396976
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/157	144/9376	0.414720452937013	PSMC3	-0.923613458750325
NA	NA	hsa04518	Integrin signaling	1/157	154/9376	0.387790553395649	ACTG1	-0.999634842199471
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/157	158/9376	0.377973071031202	GADD45B	-1.0289942198119
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/157	178/9376	0.335504186645674	JUN	-1.16801684045122
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/157	184/9376	0.324563832733315	CXCR4	-1.20748507796204
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/157	250/9376	0.23887898089172	AP2S1	-1.59175801229482
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/157	254/9376	0.235117107176889	CXCR4	-1.61272503963992
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/157	370/9376	0.16140471681873	PTGER4	-2.14773583273695