ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0140375 immune receptor activity 46/1709 156/18639 0.294871794871795 3.21598325606518 3.80620917529617e-13 3.60314773862231e-10 GO:0005126 cytokine receptor binding 65/1709 275/18639 0.236363636363636 2.57787116335975 6.11220990436355e-13 3.60314773862231e-10 GO:0042605 peptide antigen binding 20/1709 45/18639 0.444444444444444 4.84727911059099 5.30342725283109e-10 2.08424691036262e-07 GO:0044389 ubiquitin-like protein ligase binding 63/1709 322/18639 0.195652173913043 2.13385656498842 5.60282501715554e-09 1.33262847419833e-06 GO:0023023 MHC protein complex binding 17/1709 37/18639 0.459459459459459 5.01103854000285 5.65152024681224e-09 1.33262847419833e-06 GO:0003779 actin binding 78/1709 443/18639 0.17607223476298 1.92031034742374 1.30784266186971e-08 2.56991083057398e-06 GO:0023026 MHC class II protein complex binding 14/1709 27/18639 0.518518518518518 5.65515896235615 1.7936790196856e-08 3.02106794887046e-06 GO:0140297 DNA-binding transcription factor binding 83/1709 488/18639 0.170081967213115 1.85497822521079 2.2802383478678e-08 3.36050126517017e-06 GO:0003924 GTPase activity 61/1709 331/18639 0.18429003021148 2.00993673090215 9.53570353987829e-08 1.13190522790585e-05 GO:0038187 pattern recognition receptor activity 18/1709 48/18639 0.375 4.08989174956115 9.60055324771712e-08 1.13190522790585e-05 GO:0031625 ubiquitin protein ligase binding 57/1709 302/18639 0.188741721854305 2.05848856269303 1.08098006659615e-07 1.15861408956079e-05 GO:0019207 kinase regulator activity 54/1709 287/18639 0.18815331010453 2.05207112173103 2.57586825546892e-07 2.53079056099821e-05 GO:0004715 non-membrane spanning protein tyrosine kinase activity 16/1709 45/18639 0.355555555555556 3.87782328847279 1.1441339531164e-06 0.000103764148517249 GO:0048029 monosaccharide binding 21/1709 74/18639 0.283783783783784 3.09505321588411 1.84781077077506e-06 0.000155612064195985 GO:0032396 inhibitory MHC class I receptor activity 8/1709 13/18639 0.615384615384615 6.71161723004906 4.15224617934856e-06 0.000326366549696797 GO:0032395 MHC class II receptor activity 7/1709 10/18639 0.7 7.63446459918081 5.03707020327862e-06 0.000371169110604094 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 58/1709 349/18639 0.166189111747851 1.81252127201182 6.13640244733871e-06 0.000391307607120989 GO:0030695 GTPase regulator activity 75/1709 489/18639 0.153374233128834 1.6727573617837 6.19284260461608e-06 0.000391307607120989 GO:0019887 protein kinase regulator activity 46/1709 255/18639 0.180392156862745 1.96742505076928 6.30605982637727e-06 0.000391307607120989 GO:0060589 nucleoside-triphosphatase regulator activity 75/1709 490/18639 0.153061224489796 1.66934357124945 6.67178040056716e-06 0.000393301454613434 GO:0030246 carbohydrate binding 49/1709 280/18639 0.175 1.9086161497952 7.6095649056928e-06 0.000414501912199953 GO:0005125 cytokine activity 43/1709 234/18639 0.183760683760684 2.00416347841743 7.73455646174636e-06 0.000414501912199953 GO:0005164 tumor necrosis factor receptor binding 12/1709 31/18639 0.387096774193548 4.22182374148247 9.13990636657278e-06 0.000449108205273625 GO:0019003 GDP binding 20/1709 75/18639 0.266666666666667 2.90836746635459 9.14215176129516e-06 0.000449108205273625 GO:0032393 MHC class I receptor activity 9/1709 18/18639 0.5 5.45318899941486 1.01309797902512e-05 0.000477777006908245 GO:0042379 chemokine receptor binding 19/1709 72/18639 0.263888888888889 2.8780719719134 1.78891011077772e-05 0.000811201931002668 GO:0140313 molecular sequestering activity 16/1709 55/18639 0.290909090909091 3.17276450875047 2.1745175210407e-05 0.000949539317521105 GO:0032813 tumor necrosis factor receptor superfamily binding 15/1709 50/18639 0.3 3.27191339964892 2.61024584223762e-05 0.00109909994571363 GO:0061791 GTPase motor activity 13/1709 40/18639 0.325 3.54457284961966 3.49316276045683e-05 0.00137281296485953 GO:1990606 membrane scission GTPase motor activity 13/1709 40/18639 0.325 3.54457284961966 3.49316276045683e-05 0.00137281296485953 GO:0004896 cytokine receptor activity 22/1709 96/18639 0.229166666666667 2.49937829139848 4.4504919837325e-05 0.00169262259639375 GO:0035325 Toll-like receptor binding 7/1709 13/18639 0.538461538461538 5.87266507629293 5.61816951096825e-05 0.00206994432919737 GO:0005525 GTP binding 58/1709 378/18639 0.153439153439153 1.67346540722784 6.67034660986268e-05 0.00238313292516003 GO:0003925 G protein activity 15/1709 54/18639 0.277777777777778 3.02954944411937 7.06386451079662e-05 0.002418873274073 GO:0046332 SMAD binding 19/1709 79/18639 0.240506329113924 2.6230529364274 7.20972931645105e-05 0.002418873274073 GO:0051015 actin filament binding 37/1709 209/18639 0.177033492822967 1.93079419118038 7.3858725925893e-05 0.002418873274073 GO:0042277 peptide binding 42/1709 249/18639 0.168674698795181 1.83963002389899 7.93147660705435e-05 0.00252735430262624 GO:0140996 histone H3 kinase activity 55/1709 357/18639 0.15406162464986 1.6802543135452 9.12040405261804e-05 0.00278410708167883 GO:0044325 transmembrane transporter binding 27/1709 136/18639 0.198529411764706 2.1652368085912 9.50017141028476e-05 0.00278410708167883 GO:0019001 guanyl nucleotide binding 60/1709 400/18639 0.15 1.63595669982446 9.68179731542256e-05 0.00278410708167883 GO:0032561 guanyl ribonucleotide binding 60/1709 400/18639 0.15 1.63595669982446 9.68179731542256e-05 0.00278410708167883 GO:0035173 histone kinase activity 55/1709 360/18639 0.152777777777778 1.66625219426565 0.000114236318245797 0.00320677664789986 GO:0141003 histone H2AX kinase activity 54/1709 354/18639 0.152542372881356 1.6636847794825 0.000136651854727999 0.00362648822661877 GO:0008009 chemokine activity 13/1709 45/18639 0.288888888888889 3.15073142188414 0.000137184694667336 0.00362648822661877 GO:0016504 peptidase activator activity 15/1709 57/18639 0.263157894736842 2.87009947337624 0.000138415581168655 0.00362648822661877 GO:0001664 G protein-coupled receptor binding 47/1709 297/18639 0.158249158249158 1.72592513786194 0.00015171333967001 0.00388847885806394 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 12/1709 40/18639 0.3 3.27191339964892 0.000165921577668003 0.00416216042703352 GO:0050700 CARD domain binding 7/1709 15/18639 0.466666666666667 5.08964306612054 0.000178628064494587 0.0043642526941928 GO:0019864 IgG binding 6/1709 11/18639 0.545454545454545 5.94893345390712 0.000181381155229387 0.0043642526941928 GO:0061650 ubiquitin-like protein conjugating enzyme activity 12/1709 41/18639 0.292682926829268 3.19211063380382 0.000215178778429013 0.00507391559535612 GO:0001784 phosphotyrosine residue binding 13/1709 47/18639 0.276595744680851 3.01665774435716 0.000222220389188622 0.00513721252653697 GO:0005085 guanyl-nucleotide exchange factor activity 38/1709 230/18639 0.165217391304348 1.80192332154578 0.000261288505497643 0.00592421438426387 GO:0031072 heat shock protein binding 25/1709 131/18639 0.190839694656489 2.08136984710491 0.000321661640917084 0.00715545423851401 GO:0035014 phosphatidylinositol 3-kinase regulator activity 6/1709 12/18639 0.5 5.45318899941486 0.000334596472465425 0.00719883317564744 GO:0019200 carbohydrate kinase activity 8/1709 21/18639 0.380952380952381 4.15481066622085 0.000335823430585758 0.00719883317564744 GO:0070851 growth factor receptor binding 26/1709 139/18639 0.18705035971223 2.04004192783865 0.000342658579429049 0.0072141868776223 GO:0045296 cadherin binding 50/1709 334/18639 0.149700598802395 1.63269131719008 0.000372847526444379 0.00771205673119164 GO:0004857 enzyme inhibitor activity 59/1709 416/18639 0.141826923076923 1.54681803348787 0.000494105229240492 0.0100439666426645 GO:0051019 mitogen-activated protein kinase binding 9/1709 28/18639 0.321428571428571 3.50562149962384 0.000617845918737305 0.0123464464100217 GO:0016922 nuclear receptor binding 25/1709 137/18639 0.182481751824818 1.9902149632901 0.000646596130009187 0.0127056139546805 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 10/1709 34/18639 0.294117647058824 3.20775823494992 0.000686770319254382 0.0132738066623101 GO:0061134 peptidase regulator activity 36/1709 226/18639 0.15929203539823 1.73729915025606 0.000752832127716071 0.0143159528802782 GO:0004674 protein serine/threonine kinase activity 60/1709 433/18639 0.138568129330254 1.51127639706647 0.000805290598440987 0.0150704383422528 GO:0005096 GTPase activator activity 41/1709 271/18639 0.151291512915129 1.65004242786723 0.000973262207186114 0.0179293147230067 GO:0035402 histone H3T11 kinase activity 38/1709 247/18639 0.153846153846154 1.67790430751227 0.00106860482939283 0.0192684477767923 GO:0003725 double-stranded RNA binding 16/1709 75/18639 0.213333333333333 2.32669397308367 0.00107979742252652 0.0192684477767923 GO:0005131 growth hormone receptor binding 5/1709 10/18639 0.5 5.45318899941486 0.00109498388553442 0.0192684477767923 GO:0019210 kinase inhibitor activity 18/1709 90/18639 0.2 2.18127559976595 0.00120448083430336 0.0208835721124068 GO:0000149 SNARE binding 20/1709 106/18639 0.188679245283019 2.05780716959051 0.00141366142368491 0.0239327565693255 GO:0004860 protein kinase inhibitor activity 17/1709 84/18639 0.202380952380952 2.20724316642983 0.00142094398630431 0.0239327565693255 GO:0019865 immunoglobulin binding 8/1709 26/18639 0.307692307692308 3.35580861502453 0.00170181355198566 0.028259692644945 GO:0051219 phosphoprotein binding 18/1709 93/18639 0.193548387096774 2.11091187074124 0.0017789289850969 0.0290984184021355 GO:0005536 D-glucose binding 5/1709 11/18639 0.454545454545455 4.9574445449226 0.00185631949412195 0.0290984184021355 GO:0042608 T cell receptor binding 5/1709 11/18639 0.454545454545455 4.9574445449226 0.00185631949412195 0.0290984184021355 GO:0050786 RAGE receptor binding 5/1709 11/18639 0.454545454545455 4.9574445449226 0.00185631949412195 0.0290984184021355 GO:0051020 GTPase binding 45/1709 315/18639 0.142857142857143 1.55805399983282 0.00187572501998498 0.0290984184021355 GO:0019209 kinase activator activity 25/1709 148/18639 0.168918918918919 1.8422935808834 0.00201196893801373 0.0308066412716647 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 6/1709 16/18639 0.375 4.08989174956115 0.00210218070265463 0.0316215586379116 GO:0106310 protein serine kinase activity 50/1709 361/18639 0.138504155124654 1.51057867019802 0.00211936747509522 0.0316215586379116 GO:0004679 AMP-activated protein kinase activity 37/1709 248/18639 0.149193548387097 1.62716123369637 0.00214565283378535 0.0316215586379116 GO:0045309 protein phosphorylated amino acid binding 13/1709 59/18639 0.220338983050847 2.40310023703028 0.00226808614575027 0.0322254353628599 GO:0019239 deaminase activity 9/1709 33/18639 0.272727272727273 2.97446672695356 0.00226862691697826 0.0322254353628599 GO:0140311 protein sequestering activity 9/1709 33/18639 0.272727272727273 2.97446672695356 0.00226862691697826 0.0322254353628599 GO:0033691 sialic acid binding 7/1709 22/18639 0.318181818181818 3.47021118144582 0.00266794015797501 0.0342278268125962 GO:0061133 endopeptidase activator activity 7/1709 22/18639 0.318181818181818 3.47021118144582 0.00266794015797501 0.0342278268125962 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 36/1709 243/18639 0.148148148148148 1.61575970353033 0.00275439087060436 0.0342278268125962 GO:0019955 cytokine binding 24/1709 144/18639 0.166666666666667 1.81772966647162 0.00293078083784757 0.0342278268125962 GO:0004126 cytidine deaminase activity 5/1709 12/18639 0.416666666666667 4.54432416617905 0.00294326450959089 0.0342278268125962 GO:0035259 nuclear glucocorticoid receptor binding 5/1709 12/18639 0.416666666666667 4.54432416617905 0.00294326450959089 0.0342278268125962 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 6/1709 17/18639 0.352941176470588 3.8493098819399 0.00299903085041192 0.0342278268125962 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 6/1709 17/18639 0.352941176470588 3.8493098819399 0.00299903085041192 0.0342278268125962 GO:0045236 CXCR chemokine receptor binding 6/1709 17/18639 0.352941176470588 3.8493098819399 0.00299903085041192 0.0342278268125962 GO:0004676 3-phosphoinositide-dependent protein kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0004711 ribosomal protein S6 kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0035175 histone H3S10 kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0035979 histone H2AXS139 kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0044022 histone H3S28 kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0044023 histone H4S1 kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0044024 histone H2AS1 kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0044025 histone H2BS14 kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0072354 histone H3T3 kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0072371 histone H2AS121 kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0072518 Rho-dependent protein serine/threonine kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0140823 histone H2BS36 kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0140855 histone H3S57 kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0140995 histone H2A kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0140997 histone H4 kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0140998 histone H2B kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:1990244 histone H2AT120 kinase activity 36/1709 245/18639 0.146938775510204 1.60256982839947 0.00316440468411619 0.0342278268125962 GO:0004677 DNA-dependent protein kinase activity 36/1709 246/18639 0.146341463414634 1.59605531690191 0.00338828983878754 0.0359891326119866 GO:0140857 histone H3T45 kinase activity 36/1709 246/18639 0.146341463414634 1.59605531690191 0.00338828983878754 0.0359891326119866 GO:0005154 epidermal growth factor receptor binding 9/1709 35/18639 0.257142857142857 2.80449719969907 0.00351473998651842 0.0366714906557984 GO:0061631 ubiquitin conjugating enzyme activity 9/1709 35/18639 0.257142857142857 2.80449719969907 0.00351473998651842 0.0366714906557984 GO:0035403 histone H3T6 kinase activity 36/1709 247/18639 0.145748987854251 1.5895935544853 0.00362557012169492 0.0374960278375291 GO:0000287 magnesium ion binding 34/1709 230/18639 0.147826086956522 1.6122471824357 0.00367429042920585 0.0376694644872495 GO:0017124 SH3 domain binding 20/1709 115/18639 0.173913043478261 1.89676139110082 0.00383101688101223 0.038277702565368 GO:0035401 histone H3Y41 kinase activity 20/1709 115/18639 0.173913043478261 1.89676139110082 0.00383101688101223 0.038277702565368 GO:0140801 histone H2AXY142 kinase activity 20/1709 115/18639 0.173913043478261 1.89676139110082 0.00383101688101223 0.038277702565368 GO:0030295 protein kinase activator activity 23/1709 139/18639 0.165467625899281 1.8046524746265 0.00388158420569986 0.0384570401556314 GO:0016763 pentosyltransferase activity 11/1709 49/18639 0.224489795918367 2.44837057116586 0.00413525869472101 0.0406289166756339 GO:0035035 histone acetyltransferase binding 7/1709 24/18639 0.291666666666667 3.18102691632534 0.00460183609360596 0.0444718422488642 GO:0060229 lipase activator activity 7/1709 24/18639 0.291666666666667 3.18102691632534 0.00460183609360596 0.0444718422488642 GO:0003823 antigen binding 27/1709 174/18639 0.155172413793103 1.69236899981841 0.00466827518315647 0.0447471255361096 GO:0061135 endopeptidase regulator activity 28/1709 184/18639 0.152173913043478 1.65966621721322 0.00528756840180959 0.0502745414978509 GO:0034987 immunoglobulin receptor binding 6/1709 19/18639 0.315789473684211 3.44411936805149 0.00560552538604761 0.0528713154412011 GO:0030544 Hsp70 protein binding 11/1709 51/18639 0.215686274509804 2.35235603896327 0.00570748440464468 0.0534057469291752 GO:0002020 protease binding 22/1709 136/18639 0.161764705882353 1.76426702922246 0.00614078726431278 0.0570077809812974 GO:0019763 immunoglobulin receptor activity 5/1709 14/18639 0.357142857142857 3.89513499958204 0.0063683967470111 0.0586589044119225 GO:0035591 signaling adaptor activity 21/1709 129/18639 0.162790697674419 1.77545688353042 0.0067986371283161 0.0621363811960053 GO:0001614 purinergic nucleotide receptor activity 6/1709 20/18639 0.3 3.27191339964892 0.00739605017801705 0.0649589947638379 GO:0016004 phospholipase activator activity 6/1709 20/18639 0.3 3.27191339964892 0.00739605017801705 0.0649589947638379 GO:0016502 nucleotide receptor activity 6/1709 20/18639 0.3 3.27191339964892 0.00739605017801705 0.0649589947638379 GO:0016505 peptidase activator activity involved in apoptotic process 6/1709 20/18639 0.3 3.27191339964892 0.00739605017801705 0.0649589947638379 GO:0042288 MHC class I protein binding 6/1709 20/18639 0.3 3.27191339964892 0.00739605017801705 0.0649589947638379 GO:0008198 ferrous iron binding 7/1709 26/18639 0.269230769230769 2.93633253814646 0.00743805283555396 0.0649589947638379 GO:0140296 general transcription initiation factor binding 11/1709 53/18639 0.207547169811321 2.26358788654957 0.00771565170136071 0.0668878923228256 GO:0019956 chemokine binding 8/1709 33/18639 0.242424242424242 2.64397042395872 0.00849762667512654 0.0725992887679289 GO:0030296 protein tyrosine kinase activator activity 8/1709 33/18639 0.242424242424242 2.64397042395872 0.00849762667512654 0.0725992887679289 GO:0004177 aminopeptidase activity 9/1709 40/18639 0.225 2.45393504973669 0.00898425481670561 0.0762045786251504 GO:0004090 carbonyl reductase (NADPH) activity 4/1709 10/18639 0.4 4.36255119953189 0.00941341265525702 0.0765407829003312 GO:0005522 profilin binding 4/1709 10/18639 0.4 4.36255119953189 0.00941341265525702 0.0765407829003312 GO:0016175 superoxide-generating NAD(P)H oxidase activity 4/1709 10/18639 0.4 4.36255119953189 0.00941341265525702 0.0765407829003312 GO:0031720 haptoglobin binding 4/1709 10/18639 0.4 4.36255119953189 0.00941341265525702 0.0765407829003312 GO:0031996 thioesterase binding 4/1709 10/18639 0.4 4.36255119953189 0.00941341265525702 0.0765407829003312 GO:1905394 retromer complex binding 4/1709 10/18639 0.4 4.36255119953189 0.00941341265525702 0.0765407829003312 GO:0019208 phosphatase regulator activity 19/1709 117/18639 0.162393162393162 1.77112121348517 0.0099691700384825 0.0805044621600744 GO:0001530 lipopolysaccharide binding 9/1709 41/18639 0.219512195121951 2.39408297535287 0.0105969493788773 0.0838510289778274 GO:0042169 SH2 domain binding 9/1709 41/18639 0.219512195121951 2.39408297535287 0.0105969493788773 0.0838510289778274 GO:0042287 MHC protein binding 9/1709 41/18639 0.219512195121951 2.39408297535287 0.0105969493788773 0.0838510289778274 GO:0031267 small GTPase binding 38/1709 283/18639 0.134275618374558 1.46446065001954 0.0110105381784236 0.0865428300824096 GO:0008238 exopeptidase activity 17/1709 102/18639 0.166666666666667 1.81772966647162 0.0111351797656079 0.0869428936665676 GO:0005149 interleukin-1 receptor binding 5/1709 16/18639 0.3125 3.40824312463429 0.0119038475463659 0.0917296487396428 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 5/1709 16/18639 0.3125 3.40824312463429 0.0119038475463659 0.0917296487396428 GO:0004601 peroxidase activity 11/1709 57/18639 0.192982456140351 2.10473961380925 0.0133397236987674 0.101868994773234 GO:0048306 calcium-dependent protein binding 14/1709 80/18639 0.175 1.9086161497952 0.0133924463018247 0.101868994773234 GO:0001217 DNA-binding transcription repressor activity 37/1709 278/18639 0.133093525179856 1.45156829480827 0.0136789304985007 0.102466678111889 GO:0034713 type I transforming growth factor beta receptor binding 4/1709 11/18639 0.363636363636364 3.96595563593808 0.0137317516044771 0.102466678111889 GO:0140031 phosphorylation-dependent protein binding 4/1709 11/18639 0.363636363636364 3.96595563593808 0.0137317516044771 0.102466678111889 GO:0048020 CCR chemokine receptor binding 10/1709 50/18639 0.2 2.18127559976595 0.0140193009741815 0.103954439299119 GO:0005484 SNAP receptor activity 8/1709 36/18639 0.222222222222222 2.42363955529549 0.0144941659865054 0.106803885613061 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 6/1709 23/18639 0.260869565217391 2.84514208665123 0.0151924208268264 0.109888737146186 GO:0004602 glutathione peroxidase activity 6/1709 23/18639 0.260869565217391 2.84514208665123 0.0151924208268264 0.109888737146186 GO:0043274 phospholipase binding 6/1709 23/18639 0.260869565217391 2.84514208665123 0.0151924208268264 0.109888737146186 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 5/1709 17/18639 0.294117647058824 3.20775823494992 0.0156141878363467 0.112250777189346 GO:0004713 protein tyrosine kinase activity 21/1709 140/18639 0.15 1.63595669982446 0.0166887658440139 0.119248817758136 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 11/1709 59/18639 0.186440677966102 2.03339250825639 0.0171104292699343 0.121525277766581 GO:0019888 protein phosphatase regulator activity 17/1709 107/18639 0.158878504672897 1.73278902785145 0.0174843071911411 0.123437114840451 GO:0016208 AMP binding 4/1709 12/18639 0.333333333333333 3.63545933294324 0.0191259951519202 0.132644401671258 GO:0070008 serine-type exopeptidase activity 4/1709 12/18639 0.333333333333333 3.63545933294324 0.0191259951519202 0.132644401671258 GO:0097677 STAT family protein binding 4/1709 12/18639 0.333333333333333 3.63545933294324 0.0191259951519202 0.132644401671258 GO:1990841 promoter-specific chromatin binding 12/1709 68/18639 0.176470588235294 1.92465494096995 0.0198267295297392 0.136700082547149 GO:0004706 JUN kinase kinase kinase activity 5/1709 18/18639 0.277777777777778 3.02954944411937 0.0200221921382899 0.137245142622347 GO:0016251 RNA polymerase II general transcription initiation factor activity 10/1709 53/18639 0.188679245283019 2.05780716959051 0.0207408375964437 0.141349407665937 GO:0005178 integrin binding 23/1709 161/18639 0.142857142857143 1.55805399983282 0.0216992687884341 0.147031252307838 GO:0005537 D-mannose binding 6/1709 25/18639 0.24 2.61753071971913 0.0227738583748955 0.151697056632779 GO:0017025 TBP-class protein binding 6/1709 25/18639 0.24 2.61753071971913 0.0227738583748955 0.151697056632779 GO:0019211 phosphatase activator activity 6/1709 25/18639 0.24 2.61753071971913 0.0227738583748955 0.151697056632779 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 10/1709 54/18639 0.185185185185185 2.01969962941291 0.0234305003216899 0.155194156625126 GO:0016209 antioxidant activity 14/1709 86/18639 0.162790697674419 1.77545688353042 0.0241718707701664 0.15921025496104 GO:0005035 death receptor activity 4/1709 13/18639 0.307692307692308 3.35580861502453 0.0256599791042354 0.163530353318343 GO:0015651 quaternary ammonium group transmembrane transporter activity 4/1709 13/18639 0.307692307692308 3.35580861502453 0.0256599791042354 0.163530353318343 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 4/1709 13/18639 0.307692307692308 3.35580861502453 0.0256599791042354 0.163530353318343 GO:0089720 caspase binding 4/1709 13/18639 0.307692307692308 3.35580861502453 0.0256599791042354 0.163530353318343 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 4/1709 13/18639 0.307692307692308 3.35580861502453 0.0256599791042354 0.163530353318343 GO:0140852 histone ubiquitin ligase activity 4/1709 13/18639 0.307692307692308 3.35580861502453 0.0256599791042354 0.163530353318343 GO:0005200 structural constituent of cytoskeleton 17/1709 112/18639 0.151785714285714 1.65543237482237 0.0263190981866313 0.16682912237655 GO:0033293 monocarboxylic acid binding 13/1709 79/18639 0.164556962025316 1.79472043018717 0.0268948056017324 0.168097153350348 GO:0008157 protein phosphatase 1 binding 6/1709 26/18639 0.230769230769231 2.5168564612684 0.027374600036698 0.168097153350348 GO:0043548 phosphatidylinositol 3-kinase binding 6/1709 26/18639 0.230769230769231 2.5168564612684 0.027374600036698 0.168097153350348 GO:0050681 nuclear androgen receptor binding 6/1709 26/18639 0.230769230769231 2.5168564612684 0.027374600036698 0.168097153350348 GO:0070006 metalloaminopeptidase activity 6/1709 26/18639 0.230769230769231 2.5168564612684 0.027374600036698 0.168097153350348 GO:0070412 R-SMAD binding 6/1709 26/18639 0.230769230769231 2.5168564612684 0.027374600036698 0.168097153350348 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 14/1709 89/18639 0.157303370786517 1.71561002228782 0.0315171350360692 0.191539702100647 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 14/1709 89/18639 0.157303370786517 1.71561002228782 0.0315171350360692 0.191539702100647 GO:0035254 glutamate receptor binding 9/1709 49/18639 0.183673469387755 2.00321228549934 0.032196754881372 0.192897184331179 GO:0001618 virus receptor activity 13/1709 81/18639 0.160493827160494 1.75040634549119 0.032315191997657 0.192897184331179 GO:0001671 ATPase activator activity 6/1709 27/18639 0.222222222222222 2.42363955529549 0.0325495854642616 0.192897184331179 GO:0004683 calcium/calmodulin-dependent protein kinase activity 6/1709 27/18639 0.222222222222222 2.42363955529549 0.0325495854642616 0.192897184331179 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 34/1709 268/18639 0.126865671641791 1.38364497000079 0.032808242917126 0.192897184331179 GO:0004725 protein tyrosine phosphatase activity 15/1709 98/18639 0.153061224489796 1.66934357124945 0.0331520499776188 0.192897184331179 GO:0005543 phospholipid binding 58/1709 497/18639 0.116700201207243 1.27277650690568 0.0333034105807254 0.192897184331179 GO:0005161 platelet-derived growth factor receptor binding 4/1709 14/18639 0.285714285714286 3.11610799966564 0.0333766120471252 0.192897184331179 GO:0005344 oxygen carrier activity 4/1709 14/18639 0.285714285714286 3.11610799966564 0.0333766120471252 0.192897184331179 GO:0034236 protein kinase A catalytic subunit binding 4/1709 14/18639 0.285714285714286 3.11610799966564 0.0333766120471252 0.192897184331179 GO:0140793 histone H2AXY142 phosphatase activity 14/1709 90/18639 0.155555555555556 1.69654768870685 0.0342925867266607 0.197224193906015 GO:0140272 exogenous protein binding 13/1709 82/18639 0.158536585365854 1.72905992664374 0.0353023169889039 0.202045785096688 GO:0043015 gamma-tubulin binding 7/1709 35/18639 0.2 2.18127559976595 0.0369649429617197 0.210539457738491 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 5/1709 21/18639 0.238095238095238 2.59675666638803 0.0378244015053794 0.211022980761952 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 5/1709 21/18639 0.238095238095238 2.59675666638803 0.0378244015053794 0.211022980761952 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 5/1709 21/18639 0.238095238095238 2.59675666638803 0.0378244015053794 0.211022980761952 GO:0072542 protein phosphatase activator activity 5/1709 21/18639 0.238095238095238 2.59675666638803 0.0378244015053794 0.211022980761952 GO:0046625 sphingolipid binding 6/1709 28/18639 0.214285714285714 2.33708099974923 0.0383195759202142 0.211022980761952 GO:0046875 ephrin receptor binding 6/1709 28/18639 0.214285714285714 2.33708099974923 0.0383195759202142 0.211022980761952 GO:0141052 histone H3 demethylase activity 6/1709 28/18639 0.214285714285714 2.33708099974923 0.0383195759202142 0.211022980761952 GO:0001540 amyloid-beta binding 13/1709 83/18639 0.156626506024096 1.70822787933478 0.0384817140490414 0.211022980761952 GO:0019903 protein phosphatase binding 20/1709 144/18639 0.138888888888889 1.51477472205968 0.03980784738256 0.217284500296473 GO:0180051 translation factor activity 13/1709 84/18639 0.154761904761905 1.68789183315222 0.0418587658192561 0.223109557755635 GO:0019902 phosphatase binding 25/1709 190/18639 0.131578947368421 1.43504973668812 0.0420100375126507 0.223109557755635 GO:0004129 cytochrome-c oxidase activity 4/1709 15/18639 0.266666666666667 2.90836746635459 0.0422987158250956 0.223109557755635 GO:0004953 icosanoid receptor activity 4/1709 15/18639 0.266666666666667 2.90836746635459 0.0422987158250956 0.223109557755635 GO:0031386 protein tag activity 4/1709 15/18639 0.266666666666667 2.90836746635459 0.0422987158250956 0.223109557755635 GO:0141047 molecular tag activity 4/1709 15/18639 0.266666666666667 2.90836746635459 0.0422987158250956 0.223109557755635 GO:0004033 aldo-keto reductase (NADPH) activity 7/1709 36/18639 0.194444444444444 2.12068461088356 0.0423889236109094 0.223109557755635 GO:0004869 cysteine-type endopeptidase inhibitor activity 7/1709 36/18639 0.194444444444444 2.12068461088356 0.0423889236109094 0.223109557755635 GO:0035091 phosphatidylinositol binding 35/1709 284/18639 0.123239436619718 1.34409588013747 0.0441184527641692 0.23066256830575 GO:0140223 general transcription initiation factor activity 11/1709 68/18639 0.161764705882353 1.76426702922246 0.0442937234348369 0.23066256830575 GO:0031490 chromatin DNA binding 18/1709 128/18639 0.140625 1.53370940608543 0.0444108592072988 0.23066256830575 GO:0051861 glycolipid binding 6/1709 29/18639 0.206896551724138 2.25649199975787 0.0447011500748607 0.231151999729214 GO:0098531 ligand-modulated transcription factor activity 10/1709 60/18639 0.166666666666667 1.81772966647162 0.0450102036235602 0.231459758077997 GO:0030159 signaling receptor complex adaptor activity 9/1709 52/18639 0.173076923076923 1.8876423459513 0.0451533031025778 0.231459758077997 GO:0015026 coreceptor activity 10/1709 61/18639 0.163934426229508 1.78793081948028 0.0495958742763351 0.252041102464651 GO:0019905 syntaxin binding 10/1709 61/18639 0.163934426229508 1.78793081948028 0.0495958742763351 0.252041102464651 GO:0004721 phosphoprotein phosphatase activity 23/1709 175/18639 0.131428571428571 1.43340967984619 0.0500381168203826 0.253197166228459 GO:0001965 G-protein alpha-subunit binding 6/1709 30/18639 0.2 2.18127559976595 0.0517065793976836 0.258313801313004 GO:0008106 alcohol dehydrogenase (NADP+) activity 6/1709 30/18639 0.2 2.18127559976595 0.0517065793976836 0.258313801313004 GO:0032452 histone demethylase activity 6/1709 30/18639 0.2 2.18127559976595 0.0517065793976836 0.258313801313004 GO:1901981 phosphatidylinositol phosphate binding 24/1709 185/18639 0.12972972972973 1.41488147011845 0.0522680655469214 0.259728441980372 GO:0016675 oxidoreductase activity, acting on a heme group of donors 4/1709 16/18639 0.25 2.72659449970743 0.0524303385846723 0.259728441980372 GO:0042171 lysophosphatidic acid acyltransferase activity 5/1709 23/18639 0.217391304347826 2.37095173887603 0.0537593858881785 0.262997161668724 GO:0071617 lysophospholipid acyltransferase activity 5/1709 23/18639 0.217391304347826 2.37095173887603 0.0537593858881785 0.262997161668724 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 5/1709 23/18639 0.217391304347826 2.37095173887603 0.0537593858881785 0.262997161668724 GO:0015631 tubulin binding 45/1709 385/18639 0.116883116883117 1.27477145440867 0.0539928426106182 0.263047774536855 GO:0043531 ADP binding 7/1709 38/18639 0.184210526315789 2.00906963136337 0.054714243423212 0.264659102202529 GO:0004180 carboxypeptidase activity 8/1709 46/18639 0.173913043478261 1.89676139110082 0.0557206733796368 0.264659102202529 GO:0004955 prostaglandin receptor activity 3/1709 10/18639 0.3 3.27191339964892 0.056568357722678 0.264659102202529 GO:0005031 tumor necrosis factor receptor activity 3/1709 10/18639 0.3 3.27191339964892 0.056568357722678 0.264659102202529 GO:0005528 FK506 binding 3/1709 10/18639 0.3 3.27191339964892 0.056568357722678 0.264659102202529 GO:0015279 store-operated calcium channel activity 3/1709 10/18639 0.3 3.27191339964892 0.056568357722678 0.264659102202529 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 3/1709 10/18639 0.3 3.27191339964892 0.056568357722678 0.264659102202529 GO:0030957 Tat protein binding 3/1709 10/18639 0.3 3.27191339964892 0.056568357722678 0.264659102202529 GO:0043208 glycosphingolipid binding 3/1709 10/18639 0.3 3.27191339964892 0.056568357722678 0.264659102202529 GO:0070513 death domain binding 3/1709 10/18639 0.3 3.27191339964892 0.056568357722678 0.264659102202529 GO:0004197 cysteine-type endopeptidase activity 13/1709 88/18639 0.147727272727273 1.61116947709985 0.0574395419776896 0.26661897634526 GO:0016651 oxidoreductase activity, acting on NAD(P)H 13/1709 88/18639 0.147727272727273 1.61116947709985 0.0574395419776896 0.26661897634526 GO:0008234 cysteine-type peptidase activity 24/1709 187/18639 0.128342245989305 1.39974904797815 0.0578608601569709 0.26752138872576 GO:0140457 protein demethylase activity 6/1709 31/18639 0.193548387096774 2.11091187074124 0.0593437735380444 0.272814233846576 GO:0001221 transcription coregulator binding 16/1709 115/18639 0.139130434782609 1.51740911288066 0.0602884424620929 0.272814233846576 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 7/1709 39/18639 0.179487179487179 1.95755502543098 0.0616318238874871 0.272814233846576 GO:0005516 calmodulin binding 26/1709 207/18639 0.1256038647343 1.36988322690615 0.0618796692266557 0.272814233846576 GO:0141108 transporter regulator activity 22/1709 170/18639 0.129411764705882 1.41141362337796 0.062365410169295 0.272814233846576 GO:0001091 RNA polymerase II general transcription initiation factor binding 5/1709 24/18639 0.208333333333333 2.27216208308953 0.0629795885593045 0.272814233846576 GO:0019957 C-C chemokine binding 5/1709 24/18639 0.208333333333333 2.27216208308953 0.0629795885593045 0.272814233846576 GO:0042625 ATPase-coupled ion transmembrane transporter activity 5/1709 24/18639 0.208333333333333 2.27216208308953 0.0629795885593045 0.272814233846576 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 5/1709 24/18639 0.208333333333333 2.27216208308953 0.0629795885593045 0.272814233846576 GO:0046961 proton-transporting ATPase activity, rotational mechanism 5/1709 24/18639 0.208333333333333 2.27216208308953 0.0629795885593045 0.272814233846576 GO:0048027 mRNA 5'-UTR binding 5/1709 24/18639 0.208333333333333 2.27216208308953 0.0629795885593045 0.272814233846576 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 5/1709 24/18639 0.208333333333333 2.27216208308953 0.0629795885593045 0.272814233846576 GO:0004866 endopeptidase inhibitor activity 21/1709 161/18639 0.130434782608696 1.42257104332562 0.0630255965634213 0.272814233846576 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 4/1709 17/18639 0.235294117647059 2.56620658795994 0.0637583849687725 0.272814233846576 GO:0008429 phosphatidylethanolamine binding 4/1709 17/18639 0.235294117647059 2.56620658795994 0.0637583849687725 0.272814233846576 GO:0016805 dipeptidase activity 4/1709 17/18639 0.235294117647059 2.56620658795994 0.0637583849687725 0.272814233846576 GO:0019198 transmembrane receptor protein phosphatase activity 4/1709 17/18639 0.235294117647059 2.56620658795994 0.0637583849687725 0.272814233846576 GO:0036041 long-chain fatty acid binding 4/1709 17/18639 0.235294117647059 2.56620658795994 0.0637583849687725 0.272814233846576 GO:0046965 nuclear retinoid X receptor binding 4/1709 17/18639 0.235294117647059 2.56620658795994 0.0637583849687725 0.272814233846576 GO:0070492 oligosaccharide binding 4/1709 17/18639 0.235294117647059 2.56620658795994 0.0637583849687725 0.272814233846576 GO:0043177 organic acid binding 24/1709 189/18639 0.126984126984127 1.38493688874028 0.0638649097045419 0.272814233846576 GO:0009055 electron transfer activity 16/1709 116/18639 0.137931034482759 1.50432799983858 0.0642521528413706 0.273477574729155 GO:0030971 receptor tyrosine kinase binding 12/1709 81/18639 0.148148148148148 1.61575970353033 0.0649817008883826 0.275587860961881 GO:0043425 bHLH transcription factor binding 6/1709 32/18639 0.1875 2.04494587478057 0.0676162902703573 0.284712879388397 GO:0051059 NF-kappaB binding 6/1709 32/18639 0.1875 2.04494587478057 0.0676162902703573 0.284712879388397 GO:0033218 amide binding 30/1709 247/18639 0.121457489878543 1.32466129540442 0.0683130207657094 0.285921907488424 GO:1990782 protein tyrosine kinase binding 16/1709 117/18639 0.136752136752137 1.49147049556646 0.0683884460659334 0.285921907488424 GO:0015036 disulfide oxidoreductase activity 7/1709 40/18639 0.175 1.9086161497952 0.069059060304443 0.286692366545557 GO:0032451 demethylase activity 7/1709 40/18639 0.175 1.9086161497952 0.069059060304443 0.286692366545557 GO:0140789 histone phosphatase activity 18/1709 136/18639 0.132352941176471 1.44349120572746 0.0720962915774178 0.290282129610329 GO:0043130 ubiquitin binding 14/1709 100/18639 0.14 1.52689291983616 0.0722285340346878 0.290282129610329 GO:0003953 NAD+ nucleosidase activity 3/1709 11/18639 0.272727272727273 2.97446672695356 0.0726320850170033 0.290282129610329 GO:0004954 prostanoid receptor activity 3/1709 11/18639 0.272727272727273 2.97446672695356 0.0726320850170033 0.290282129610329 GO:0008199 ferric iron binding 3/1709 11/18639 0.272727272727273 2.97446672695356 0.0726320850170033 0.290282129610329 GO:0010854 adenylate cyclase regulator activity 3/1709 11/18639 0.272727272727273 2.97446672695356 0.0726320850170033 0.290282129610329 GO:0016176 superoxide-generating NADPH oxidase activator activity 3/1709 11/18639 0.272727272727273 2.97446672695356 0.0726320850170033 0.290282129610329 GO:0019107 myristoyltransferase activity 3/1709 11/18639 0.272727272727273 2.97446672695356 0.0726320850170033 0.290282129610329 GO:0047676 arachidonate-CoA ligase activity 3/1709 11/18639 0.272727272727273 2.97446672695356 0.0726320850170033 0.290282129610329 GO:0070697 activin receptor binding 3/1709 11/18639 0.272727272727273 2.97446672695356 0.0726320850170033 0.290282129610329 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 3/1709 11/18639 0.272727272727273 2.97446672695356 0.0726320850170033 0.290282129610329 GO:0004709 MAP kinase kinase kinase activity 5/1709 25/18639 0.2 2.18127559976595 0.0730310211054066 0.29089045230836 GO:0008135 translation factor activity, RNA binding 12/1709 83/18639 0.144578313253012 1.57682573477056 0.0754083920974222 0.29769531402155 GO:0001222 transcription corepressor binding 8/1709 49/18639 0.163265306122449 1.78063314266608 0.0758048163260324 0.29769531402155 GO:0003746 translation elongation factor activity 4/1709 18/18639 0.222222222222222 2.42363955529549 0.0762544400631961 0.29769531402155 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 4/1709 18/18639 0.222222222222222 2.42363955529549 0.0762544400631961 0.29769531402155 GO:0017075 syntaxin-1 binding 4/1709 18/18639 0.222222222222222 2.42363955529549 0.0762544400631961 0.29769531402155 GO:0098641 cadherin binding involved in cell-cell adhesion 4/1709 18/18639 0.222222222222222 2.42363955529549 0.0762544400631961 0.29769531402155 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 6/1709 33/18639 0.181818181818182 1.98297781796904 0.0765234039431814 0.297759383660102 GO:0017080 sodium channel regulator activity 7/1709 41/18639 0.170731707317073 1.86206453638556 0.0769973753775052 0.298201065341457 GO:0008235 metalloexopeptidase activity 10/1709 66/18639 0.151515151515152 1.6524815149742 0.0771427692359155 0.298201065341457 GO:0051117 ATPase binding 12/1709 84/18639 0.142857142857143 1.55805399983282 0.0809999964771166 0.312088221720655 GO:0051213 dioxygenase activity 13/1709 93/18639 0.139784946236559 1.524547462202 0.0818589532705203 0.31437037754379 GO:0001637 G protein-coupled chemoattractant receptor activity 5/1709 26/18639 0.192307692307692 2.09738038439033 0.0839015975503374 0.318070686533273 GO:0004950 chemokine receptor activity 5/1709 26/18639 0.192307692307692 2.09738038439033 0.0839015975503374 0.318070686533273 GO:0005160 transforming growth factor beta receptor binding 5/1709 26/18639 0.192307692307692 2.09738038439033 0.0839015975503374 0.318070686533273 GO:0030247 polysaccharide binding 5/1709 26/18639 0.192307692307692 2.09738038439033 0.0839015975503374 0.318070686533273 GO:0048487 beta-tubulin binding 7/1709 42/18639 0.166666666666667 1.81772966647162 0.0854455289891883 0.321268438409713 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 17/1709 130/18639 0.130769230769231 1.42621866138543 0.0859087666051535 0.321268438409713 GO:0051427 hormone receptor binding 6/1709 34/18639 0.176470588235294 1.92465494096995 0.0860602259736855 0.321268438409713 GO:0004540 RNA nuclease activity 16/1709 121/18639 0.132231404958678 1.44216568579567 0.0866957973907282 0.321268438409713 GO:0004879 nuclear receptor activity 9/1709 59/18639 0.152542372881356 1.6636847794825 0.0876087911525117 0.321268438409713 GO:0031593 polyubiquitin modification-dependent protein binding 9/1709 59/18639 0.152542372881356 1.6636847794825 0.0876087911525117 0.321268438409713 GO:0016247 channel regulator activity 21/1709 168/18639 0.125 1.36329724985372 0.0895677563132603 0.321268438409713 GO:0031420 alkali metal ion binding 4/1709 19/18639 0.210526315789474 2.29607957870099 0.0898766902953385 0.321268438409713 GO:0042834 peptidoglycan binding 4/1709 19/18639 0.210526315789474 2.29607957870099 0.0898766902953385 0.321268438409713 GO:0070003 threonine-type peptidase activity 4/1709 19/18639 0.210526315789474 2.29607957870099 0.0898766902953385 0.321268438409713 GO:0097001 ceramide binding 4/1709 19/18639 0.210526315789474 2.29607957870099 0.0898766902953385 0.321268438409713 GO:0031406 carboxylic acid binding 23/1709 187/18639 0.122994652406417 1.34142617097906 0.0901452764689428 0.321268438409713 GO:0004875 complement receptor activity 3/1709 12/18639 0.25 2.72659449970743 0.0904674483053645 0.321268438409713 GO:0005527 macrolide binding 3/1709 12/18639 0.25 2.72659449970743 0.0904674483053645 0.321268438409713 GO:0008603 cAMP-dependent protein kinase regulator activity 3/1709 12/18639 0.25 2.72659449970743 0.0904674483053645 0.321268438409713 GO:0015269 calcium-activated potassium channel activity 3/1709 12/18639 0.25 2.72659449970743 0.0904674483053645 0.321268438409713 GO:0035497 cAMP response element binding 3/1709 12/18639 0.25 2.72659449970743 0.0904674483053645 0.321268438409713 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 3/1709 12/18639 0.25 2.72659449970743 0.0904674483053645 0.321268438409713 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 3/1709 12/18639 0.25 2.72659449970743 0.0904674483053645 0.321268438409713 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 3/1709 12/18639 0.25 2.72659449970743 0.0904674483053645 0.321268438409713 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 3/1709 12/18639 0.25 2.72659449970743 0.0904674483053645 0.321268438409713 GO:0030414 peptidase inhibitor activity 21/1709 169/18639 0.124260355029586 1.35523040222144 0.093877287707794 0.332376342965433 GO:0048156 tau protein binding 7/1709 43/18639 0.162790697674419 1.77545688353042 0.094399669324419 0.332800524552225 GO:0001098 basal transcription machinery binding 9/1709 60/18639 0.15 1.63595669982446 0.0951261889517386 0.332800524552225 GO:0001099 basal RNA polymerase II transcription machinery binding 9/1709 60/18639 0.15 1.63595669982446 0.0951261889517386 0.332800524552225 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 9/1709 60/18639 0.15 1.63595669982446 0.0951261889517386 0.332800524552225 GO:0035255 ionotropic glutamate receptor binding 5/1709 27/18639 0.185185185185185 2.01969962941291 0.0955725093880819 0.333372747244226 GO:0020037 heme binding 18/1709 142/18639 0.126760563380282 1.38249861956997 0.0991981509863183 0.34499887909401 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 8/1709 52/18639 0.153846153846154 1.67790430751227 0.0997173358542029 0.345784526388545 GO:0003712 transcription coregulator activity 54/1709 495/18639 0.109090909090909 1.18978669078142 0.102139471128772 0.352762546141764 GO:0046906 tetrapyrrole binding 19/1709 152/18639 0.125 1.36329724985372 0.102328066819748 0.352762546141764 GO:0001046 core promoter sequence-specific DNA binding 7/1709 44/18639 0.159090909090909 1.73510559072291 0.103853407724141 0.35593944100803 GO:0030547 signaling receptor inhibitor activity 7/1709 44/18639 0.159090909090909 1.73510559072291 0.103853407724141 0.35593944100803 GO:0030742 GTP-dependent protein binding 4/1709 20/18639 0.2 2.18127559976595 0.104571866486454 0.356330146206731 GO:0043024 ribosomal small subunit binding 4/1709 20/18639 0.2 2.18127559976595 0.104571866486454 0.356330146206731 GO:0097110 scaffold protein binding 10/1709 70/18639 0.142857142857143 1.55805399983282 0.104887215656073 0.356374718324236 GO:0051087 protein-folding chaperone binding 17/1709 134/18639 0.126865671641791 1.38364497000079 0.106124237702538 0.359541598423255 GO:0016409 palmitoyltransferase activity 6/1709 36/18639 0.166666666666667 1.81772966647162 0.106983660159556 0.361414714407212 GO:0046966 nuclear thyroid hormone receptor binding 5/1709 28/18639 0.178571428571429 1.94756749979102 0.108018799272401 0.361965149185654 GO:0005246 calcium channel regulator activity 8/1709 53/18639 0.150943396226415 1.64624573567241 0.108529882324976 0.361965149185654 GO:0051018 protein kinase A binding 8/1709 53/18639 0.150943396226415 1.64624573567241 0.108529882324976 0.361965149185654 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 3/1709 13/18639 0.230769230769231 2.5168564612684 0.109909689065703 0.361965149185654 GO:0019855 calcium channel inhibitor activity 3/1709 13/18639 0.230769230769231 2.5168564612684 0.109909689065703 0.361965149185654 GO:0030955 potassium ion binding 3/1709 13/18639 0.230769230769231 2.5168564612684 0.109909689065703 0.361965149185654 GO:0031432 titin binding 3/1709 13/18639 0.230769230769231 2.5168564612684 0.109909689065703 0.361965149185654 GO:0043560 insulin receptor substrate binding 3/1709 13/18639 0.230769230769231 2.5168564612684 0.109909689065703 0.361965149185654 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 3/1709 13/18639 0.230769230769231 2.5168564612684 0.109909689065703 0.361965149185654 GO:0051287 NAD binding 8/1709 54/18639 0.148148148148148 1.61575970353033 0.117754207201843 0.385426696234427 GO:0140463 chromatin-protein adaptor activity 8/1709 54/18639 0.148148148148148 1.61575970353033 0.117754207201843 0.385426696234427 GO:0042805 actinin binding 6/1709 37/18639 0.162162162162162 1.76860183764806 0.118341360506245 0.385426696234427 GO:0043394 proteoglycan binding 6/1709 37/18639 0.162162162162162 1.76860183764806 0.118341360506245 0.385426696234427 GO:0008373 sialyltransferase activity 4/1709 21/18639 0.19047619047619 2.07740533311042 0.120277152364354 0.388511678459105 GO:0009931 calcium-dependent protein serine/threonine kinase activity 4/1709 21/18639 0.19047619047619 2.07740533311042 0.120277152364354 0.388511678459105 GO:0051010 microtubule plus-end binding 4/1709 21/18639 0.19047619047619 2.07740533311042 0.120277152364354 0.388511678459105 GO:0003785 actin monomer binding 5/1709 29/18639 0.172413793103448 1.88040999979823 0.121209976188555 0.389391176910917 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 5/1709 29/18639 0.172413793103448 1.88040999979823 0.121209976188555 0.389391176910917 GO:0004521 RNA endonuclease activity 10/1709 73/18639 0.136986301369863 1.49402438340133 0.129007373747184 0.413314384912853 GO:0008191 metalloendopeptidase inhibitor activity 3/1709 14/18639 0.214285714285714 2.33708099974923 0.130782346434406 0.413384414064786 GO:0008494 translation activator activity 3/1709 14/18639 0.214285714285714 2.33708099974923 0.130782346434406 0.413384414064786 GO:0016530 metallochaperone activity 3/1709 14/18639 0.214285714285714 2.33708099974923 0.130782346434406 0.413384414064786 GO:0044548 S100 protein binding 3/1709 14/18639 0.214285714285714 2.33708099974923 0.130782346434406 0.413384414064786 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 3/1709 14/18639 0.214285714285714 2.33708099974923 0.130782346434406 0.413384414064786 GO:0032182 ubiquitin-like protein binding 15/1709 120/18639 0.125 1.36329724985372 0.134808150104699 0.422539895509648 GO:0001968 fibronectin binding 5/1709 30/18639 0.166666666666667 1.81772966647162 0.135110655546729 0.422539895509648 GO:0033612 receptor serine/threonine kinase binding 5/1709 30/18639 0.166666666666667 1.81772966647162 0.135110655546729 0.422539895509648 GO:0005504 fatty acid binding 7/1709 47/18639 0.148936170212766 1.62435417003847 0.135112417817759 0.422539895509648 GO:0050321 tau-protein kinase activity 4/1709 22/18639 0.181818181818182 1.98297781796904 0.136922016656709 0.425939466064011 GO:0140517 protein-RNA adaptor activity 4/1709 22/18639 0.181818181818182 1.98297781796904 0.136922016656709 0.425939466064011 GO:0038024 cargo receptor activity 9/1709 65/18639 0.138461538461538 1.51011387676104 0.138071051894124 0.42838360574519 GO:0099106 ion channel regulator activity 19/1709 160/18639 0.11875 1.29513238736103 0.146388353512066 0.45201274089765 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 7/1709 48/18639 0.145833333333333 1.59051345816267 0.146453661597033 0.45201274089765 GO:0016411 acylglycerol O-acyltransferase activity 5/1709 31/18639 0.161290322580645 1.7590932256177 0.149681209779169 0.460768006082611 GO:0004467 long-chain fatty acid-CoA ligase activity 3/1709 15/18639 0.2 2.18127559976595 0.152903254086734 0.464620970536751 GO:0005523 tropomyosin binding 3/1709 15/18639 0.2 2.18127559976595 0.152903254086734 0.464620970536751 GO:0017081 chloride channel regulator activity 3/1709 15/18639 0.2 2.18127559976595 0.152903254086734 0.464620970536751 GO:0051371 muscle alpha-actinin binding 3/1709 15/18639 0.2 2.18127559976595 0.152903254086734 0.464620970536751 GO:0140776 protein-containing complex destabilizing activity 3/1709 15/18639 0.2 2.18127559976595 0.152903254086734 0.464620970536751 GO:0016493 C-C chemokine receptor activity 4/1709 23/18639 0.173913043478261 1.89676139110082 0.154429938923768 0.468053722342218 GO:0071949 FAD binding 6/1709 40/18639 0.15 1.63595669982446 0.155755902373666 0.469928800035652 GO:0017022 myosin binding 10/1709 76/18639 0.131578947368421 1.43504973668812 0.155845768290025 0.469928800035652 GO:0060590 ATPase regulator activity 7/1709 49/18639 0.142857142857143 1.55805399983282 0.1582284691422 0.475896339588404 GO:0016407 acetyltransferase activity 12/1709 96/18639 0.125 1.36329724985372 0.167683513668401 0.503050541005204 GO:0005540 hyaluronic acid binding 4/1709 24/18639 0.166666666666667 1.81772966647162 0.172720008996661 0.512939271050538 GO:0015149 hexose transmembrane transporter activity 4/1709 24/18639 0.166666666666667 1.81772966647162 0.172720008996661 0.512939271050538 GO:0050699 WW domain binding 4/1709 24/18639 0.166666666666667 1.81772966647162 0.172720008996661 0.512939271050538 GO:0055056 D-glucose transmembrane transporter activity 4/1709 24/18639 0.166666666666667 1.81772966647162 0.172720008996661 0.512939271050538 GO:0005521 lamin binding 3/1709 16/18639 0.1875 2.04494587478057 0.176089311510287 0.51902324567657 GO:0031435 mitogen-activated protein kinase kinase kinase binding 3/1709 16/18639 0.1875 2.04494587478057 0.176089311510287 0.51902324567657 GO:0070411 I-SMAD binding 3/1709 16/18639 0.1875 2.04494587478057 0.176089311510287 0.51902324567657 GO:0071889 14-3-3 protein binding 5/1709 33/18639 0.151515151515152 1.6524815149742 0.180656098015693 0.531155959003746 GO:0003743 translation initiation factor activity 7/1709 51/18639 0.137254901960784 1.49695384297663 0.183001097676849 0.534711529540336 GO:0042056 chemoattractant activity 6/1709 42/18639 0.142857142857143 1.55805399983282 0.183226003336977 0.534711529540336 GO:0051879 Hsp90 protein binding 6/1709 42/18639 0.142857142857143 1.55805399983282 0.183226003336977 0.534711529540336 GO:0019787 ubiquitin-like protein transferase activity 50/1709 479/18639 0.104384133611691 1.13845281824945 0.184154554573598 0.536094369980919 GO:0004519 endonuclease activity 15/1709 127/18639 0.118110236220472 1.28815488175154 0.186279662198163 0.540945127417817 GO:0008017 microtubule binding 30/1709 276/18639 0.108695652173913 1.18547586943801 0.187247246419427 0.542418927588462 GO:0003713 transcription coactivator activity 28/1709 256/18639 0.109375 1.192885093622 0.187927742183944 0.54305590204625 GO:0003727 single-stranded RNA binding 11/1709 89/18639 0.123595505617978 1.34797930322615 0.190497926147286 0.545952147417011 GO:0019706 protein-cysteine S-palmitoyltransferase activity 4/1709 25/18639 0.16 1.74502047981276 0.191708387642614 0.545952147417011 GO:0019707 protein-cysteine S-acyltransferase activity 4/1709 25/18639 0.16 1.74502047981276 0.191708387642614 0.545952147417011 GO:0042974 nuclear retinoic acid receptor binding 4/1709 25/18639 0.16 1.74502047981276 0.191708387642614 0.545952147417011 GO:0047617 fatty acyl-CoA hydrolase activity 4/1709 25/18639 0.16 1.74502047981276 0.191708387642614 0.545952147417011 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 4/1709 25/18639 0.16 1.74502047981276 0.191708387642614 0.545952147417011 GO:0005080 protein kinase C binding 7/1709 52/18639 0.134615384615385 1.46816626907323 0.195956349515928 0.556577604947124 GO:0019825 oxygen binding 5/1709 34/18639 0.147058823529412 1.60387911747496 0.196965731126384 0.556577604947124 GO:0004029 aldehyde dehydrogenase (NAD+) activity 3/1709 17/18639 0.176470588235294 1.92465494096995 0.200160224340611 0.556577604947124 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 3/1709 17/18639 0.176470588235294 1.92465494096995 0.200160224340611 0.556577604947124 GO:0005092 GDP-dissociation inhibitor activity 3/1709 17/18639 0.176470588235294 1.92465494096995 0.200160224340611 0.556577604947124 GO:0017110 nucleoside diphosphate phosphatase activity 3/1709 17/18639 0.176470588235294 1.92465494096995 0.200160224340611 0.556577604947124 GO:0031489 myosin V binding 3/1709 17/18639 0.176470588235294 1.92465494096995 0.200160224340611 0.556577604947124 GO:0038191 neuropilin binding 3/1709 17/18639 0.176470588235294 1.92465494096995 0.200160224340611 0.556577604947124 GO:0045125 bioactive lipid receptor activity 3/1709 17/18639 0.176470588235294 1.92465494096995 0.200160224340611 0.556577604947124 GO:0048038 quinone binding 3/1709 17/18639 0.176470588235294 1.92465494096995 0.200160224340611 0.556577604947124 GO:0140104 molecular carrier activity 27/1709 249/18639 0.108433734939759 1.18261930107792 0.205636996964045 0.570461222166139 GO:0004518 nuclease activity 23/1709 209/18639 0.110047846889952 1.20022341613916 0.207201138082206 0.57345103708667 GO:0005544 calcium-dependent phospholipid binding 7/1709 53/18639 0.132075471698113 1.44046501871336 0.209260377131942 0.576699177267394 GO:0004435 phosphatidylinositol phospholipase C activity 4/1709 26/18639 0.153846153846154 1.67790430751227 0.211309622204847 0.576699177267394 GO:0005227 calcium-activated cation channel activity 4/1709 26/18639 0.153846153846154 1.67790430751227 0.211309622204847 0.576699177267394 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 4/1709 26/18639 0.153846153846154 1.67790430751227 0.211309622204847 0.576699177267394 GO:0015145 monosaccharide transmembrane transporter activity 4/1709 26/18639 0.153846153846154 1.67790430751227 0.211309622204847 0.576699177267394 GO:0016289 acyl-CoA hydrolase activity 4/1709 26/18639 0.153846153846154 1.67790430751227 0.211309622204847 0.576699177267394 GO:0016755 aminoacyltransferase activity 51/1709 496/18639 0.102822580645161 1.12142193133128 0.211934682163817 0.577069261596167 GO:1902936 phosphatidylinositol bisphosphate binding 13/1709 111/18639 0.117117117117117 1.27732354941249 0.216157599492426 0.586599591161091 GO:0042578 phosphoric ester hydrolase activity 38/1709 363/18639 0.104683195592287 1.1417145012549 0.21642987460142 0.586599591161091 GO:0005507 copper ion binding 8/1709 63/18639 0.126984126984127 1.38493688874028 0.217514409205824 0.588186900123088 GO:0043539 protein serine/threonine kinase activator activity 9/1709 73/18639 0.123287671232877 1.3446219450612 0.223496430392687 0.593020641391067 GO:0008525 phosphatidylcholine transporter activity 3/1709 18/18639 0.166666666666667 1.81772966647162 0.224941381196094 0.593020641391067 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 3/1709 18/18639 0.166666666666667 1.81772966647162 0.224941381196094 0.593020641391067 GO:0016854 racemase and epimerase activity 3/1709 18/18639 0.166666666666667 1.81772966647162 0.224941381196094 0.593020641391067 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 3/1709 18/18639 0.166666666666667 1.81772966647162 0.224941381196094 0.593020641391067 GO:0030228 lipoprotein particle receptor activity 3/1709 18/18639 0.166666666666667 1.81772966647162 0.224941381196094 0.593020641391067 GO:0050811 GABA receptor binding 3/1709 18/18639 0.166666666666667 1.81772966647162 0.224941381196094 0.593020641391067 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 3/1709 18/18639 0.166666666666667 1.81772966647162 0.224941381196094 0.593020641391067 GO:0141110 transporter inhibitor activity 6/1709 45/18639 0.133333333333333 1.4541837331773 0.227612413837855 0.593020641391067 GO:0008083 growth factor activity 18/1709 162/18639 0.111111111111111 1.21181977764775 0.229240099767522 0.593020641391067 GO:0004364 glutathione transferase activity 4/1709 27/18639 0.148148148148148 1.61575970353033 0.231437815738197 0.593020641391067 GO:0008266 poly(U) RNA binding 4/1709 27/18639 0.148148148148148 1.61575970353033 0.231437815738197 0.593020641391067 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 4/1709 27/18639 0.148148148148148 1.61575970353033 0.231437815738197 0.593020641391067 GO:0001094 TFIID-class transcription factor complex binding 2/1709 10/18639 0.2 2.18127559976595 0.231876603631282 0.593020641391067 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/1709 10/18639 0.2 2.18127559976595 0.231876603631282 0.593020641391067 GO:0005345 purine nucleobase transmembrane transporter activity 2/1709 10/18639 0.2 2.18127559976595 0.231876603631282 0.593020641391067 GO:0005381 iron ion transmembrane transporter activity 2/1709 10/18639 0.2 2.18127559976595 0.231876603631282 0.593020641391067 GO:0008190 eukaryotic initiation factor 4E binding 2/1709 10/18639 0.2 2.18127559976595 0.231876603631282 0.593020641391067 GO:0035256 G protein-coupled glutamate receptor binding 2/1709 10/18639 0.2 2.18127559976595 0.231876603631282 0.593020641391067 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/1709 10/18639 0.2 2.18127559976595 0.231876603631282 0.593020641391067 GO:0043422 protein kinase B binding 2/1709 10/18639 0.2 2.18127559976595 0.231876603631282 0.593020641391067 GO:0050308 sugar-phosphatase activity 2/1709 10/18639 0.2 2.18127559976595 0.231876603631282 0.593020641391067 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/1709 10/18639 0.2 2.18127559976595 0.231876603631282 0.593020641391067 GO:0071723 lipopeptide binding 2/1709 10/18639 0.2 2.18127559976595 0.231876603631282 0.593020641391067 GO:1990757 ubiquitin ligase activator activity 2/1709 10/18639 0.2 2.18127559976595 0.231876603631282 0.593020641391067 GO:0001216 DNA-binding transcription activator activity 50/1709 491/18639 0.10183299389002 1.11062912411708 0.235683095312593 0.60145101596006 GO:0140030 modification-dependent protein binding 19/1709 173/18639 0.109826589595376 1.19781030044951 0.236842583954394 0.603030195125769 GO:0003774 cytoskeletal motor activity 17/1709 153/18639 0.111111111111111 1.21181977764775 0.237324860507512 0.603030195125769 GO:0030291 protein serine/threonine kinase inhibitor activity 6/1709 46/18639 0.130434782608696 1.42257104332562 0.243120970660869 0.616429299804654 GO:0005506 iron ion binding 17/1709 154/18639 0.11038961038961 1.20395081805263 0.245646278911548 0.621495628404969 GO:0005520 insulin-like growth factor binding 3/1709 19/18639 0.157894736842105 1.72205968402575 0.250266010739986 0.622886837507051 GO:0030506 ankyrin binding 3/1709 19/18639 0.157894736842105 1.72205968402575 0.250266010739986 0.622886837507051 GO:0043395 heparan sulfate proteoglycan binding 3/1709 19/18639 0.157894736842105 1.72205968402575 0.250266010739986 0.622886837507051 GO:0050145 nucleoside monophosphate kinase activity 3/1709 19/18639 0.157894736842105 1.72205968402575 0.250266010739986 0.622886837507051 GO:0019212 phosphatase inhibitor activity 7/1709 56/18639 0.125 1.36329724985372 0.25101873622915 0.622886837507051 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 49/1709 484/18639 0.101239669421488 1.10415810318731 0.251566175468982 0.622886837507051 GO:0045499 chemorepellent activity 4/1709 28/18639 0.142857142857143 1.55805399983282 0.25200765181583 0.622886837507051 GO:0051119 sugar transmembrane transporter activity 4/1709 28/18639 0.142857142857143 1.55805399983282 0.25200765181583 0.622886837507051 GO:0051393 alpha-actinin binding 4/1709 28/18639 0.142857142857143 1.55805399983282 0.25200765181583 0.622886837507051 GO:0051959 dynein light intermediate chain binding 4/1709 28/18639 0.142857142857143 1.55805399983282 0.25200765181583 0.622886837507051 GO:0097718 disordered domain specific binding 4/1709 28/18639 0.142857142857143 1.55805399983282 0.25200765181583 0.622886837507051 GO:0043495 protein-membrane adaptor activity 6/1709 47/18639 0.127659574468085 1.39230357431869 0.258927100345226 0.636574908198431 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 10/1709 86/18639 0.116279069767442 1.26818348823601 0.262097667679338 0.636574908198431 GO:0005501 retinoid binding 5/1709 38/18639 0.131578947368421 1.43504973668812 0.266503368941072 0.636574908198431 GO:0019840 isoprenoid binding 5/1709 38/18639 0.131578947368421 1.43504973668812 0.266503368941072 0.636574908198431 GO:0001851 complement component C3b binding 2/1709 11/18639 0.181818181818182 1.98297781796904 0.267264274434456 0.636574908198431 GO:0005114 type II transforming growth factor beta receptor binding 2/1709 11/18639 0.181818181818182 1.98297781796904 0.267264274434456 0.636574908198431 GO:0008526 phosphatidylinositol transfer activity 2/1709 11/18639 0.181818181818182 1.98297781796904 0.267264274434456 0.636574908198431 GO:0015205 nucleobase transmembrane transporter activity 2/1709 11/18639 0.181818181818182 1.98297781796904 0.267264274434456 0.636574908198431 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 2/1709 11/18639 0.181818181818182 1.98297781796904 0.267264274434456 0.636574908198431 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/1709 11/18639 0.181818181818182 1.98297781796904 0.267264274434456 0.636574908198431 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/1709 11/18639 0.181818181818182 1.98297781796904 0.267264274434456 0.636574908198431 GO:0019203 carbohydrate phosphatase activity 2/1709 11/18639 0.181818181818182 1.98297781796904 0.267264274434456 0.636574908198431 GO:0019215 intermediate filament binding 2/1709 11/18639 0.181818181818182 1.98297781796904 0.267264274434456 0.636574908198431 GO:0031731 CCR6 chemokine receptor binding 2/1709 11/18639 0.181818181818182 1.98297781796904 0.267264274434456 0.636574908198431 GO:0043522 leucine zipper domain binding 2/1709 11/18639 0.181818181818182 1.98297781796904 0.267264274434456 0.636574908198431 GO:0050998 nitric-oxide synthase binding 2/1709 11/18639 0.181818181818182 1.98297781796904 0.267264274434456 0.636574908198431 GO:0097493 structural molecule activity conferring elasticity 2/1709 11/18639 0.181818181818182 1.98297781796904 0.267264274434456 0.636574908198431 GO:0140537 transcription regulator activator activity 2/1709 11/18639 0.181818181818182 1.98297781796904 0.267264274434456 0.636574908198431 GO:0004629 phospholipase C activity 4/1709 29/18639 0.137931034482759 1.50432799983858 0.272935279916194 0.646166054259422 GO:0016417 S-acyltransferase activity 4/1709 29/18639 0.137931034482759 1.50432799983858 0.272935279916194 0.646166054259422 GO:0043236 laminin binding 4/1709 29/18639 0.137931034482759 1.50432799983858 0.272935279916194 0.646166054259422 GO:0001972 retinoic acid binding 3/1709 20/18639 0.15 1.63595669982446 0.275976742078844 0.648160515758879 GO:0010851 cyclase regulator activity 3/1709 20/18639 0.15 1.63595669982446 0.275976742078844 0.648160515758879 GO:0016408 C-acyltransferase activity 3/1709 20/18639 0.15 1.63595669982446 0.275976742078844 0.648160515758879 GO:0031418 L-ascorbic acid binding 3/1709 20/18639 0.15 1.63595669982446 0.275976742078844 0.648160515758879 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 8/1709 68/18639 0.117647058823529 1.28310329397997 0.283225162010926 0.662544575418417 GO:0030145 manganese ion binding 8/1709 68/18639 0.117647058823529 1.28310329397997 0.283225162010926 0.662544575418417 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 5/1709 39/18639 0.128205128205128 1.39825358959355 0.2847021914231 0.663895431439395 GO:0022853 active monoatomic ion transmembrane transporter activity 13/1709 118/18639 0.110169491525424 1.20155011851514 0.284928828081708 0.663895431439395 GO:0016791 phosphatase activity 28/1709 273/18639 0.102564102564103 1.11860287167484 0.293983940267969 0.676860081332287 GO:0008187 poly-pyrimidine tract binding 4/1709 30/18639 0.133333333333333 1.4541837331773 0.294139068280727 0.676860081332287 GO:0022839 monoatomic ion-gated channel activity 4/1709 30/18639 0.133333333333333 1.4541837331773 0.294139068280727 0.676860081332287 GO:0035925 mRNA 3'-UTR AU-rich region binding 4/1709 30/18639 0.133333333333333 1.4541837331773 0.294139068280727 0.676860081332287 GO:0070566 adenylyltransferase activity 4/1709 30/18639 0.133333333333333 1.4541837331773 0.294139068280727 0.676860081332287 GO:0015459 potassium channel regulator activity 7/1709 59/18639 0.11864406779661 1.29397705070861 0.295001509692858 0.676860081332287 GO:0001846 opsonin binding 3/1709 21/18639 0.142857142857143 1.55805399983282 0.301926673697926 0.676860081332287 GO:0005123 death receptor binding 3/1709 21/18639 0.142857142857143 1.55805399983282 0.301926673697926 0.676860081332287 GO:0004000 adenosine deaminase activity 2/1709 12/18639 0.166666666666667 1.81772966647162 0.302623639660274 0.676860081332287 GO:0004859 phospholipase inhibitor activity 2/1709 12/18639 0.166666666666667 1.81772966647162 0.302623639660274 0.676860081332287 GO:0008179 adenylate cyclase binding 2/1709 12/18639 0.166666666666667 1.81772966647162 0.302623639660274 0.676860081332287 GO:0010853 cyclase activator activity 2/1709 12/18639 0.166666666666667 1.81772966647162 0.302623639660274 0.676860081332287 GO:0015368 calcium:monoatomic cation antiporter activity 2/1709 12/18639 0.166666666666667 1.81772966647162 0.302623639660274 0.676860081332287 GO:0016840 carbon-nitrogen lyase activity 2/1709 12/18639 0.166666666666667 1.81772966647162 0.302623639660274 0.676860081332287 GO:0031543 peptidyl-proline dioxygenase activity 2/1709 12/18639 0.166666666666667 1.81772966647162 0.302623639660274 0.676860081332287 GO:0042301 phosphate ion binding 2/1709 12/18639 0.166666666666667 1.81772966647162 0.302623639660274 0.676860081332287 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 2/1709 12/18639 0.166666666666667 1.81772966647162 0.302623639660274 0.676860081332287 GO:0070679 inositol 1,4,5 trisphosphate binding 2/1709 12/18639 0.166666666666667 1.81772966647162 0.302623639660274 0.676860081332287 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 2/1709 12/18639 0.166666666666667 1.81772966647162 0.302623639660274 0.676860081332287 GO:0015144 carbohydrate transmembrane transporter activity 5/1709 40/18639 0.125 1.36329724985372 0.303123089858734 0.676860081332287 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 5/1709 40/18639 0.125 1.36329724985372 0.303123089858734 0.676860081332287 GO:0030331 nuclear estrogen receptor binding 5/1709 40/18639 0.125 1.36329724985372 0.303123089858734 0.676860081332287 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 7/1709 60/18639 0.116666666666667 1.27241076653013 0.310032243121463 0.690979233724396 GO:0140674 ATP-dependent histone chaperone activity 16/1709 152/18639 0.105263157894737 1.1480397893505 0.318685150145085 0.70835629925158 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/1709 41/18639 0.121951219512195 1.33004609741826 0.321715551763497 0.70835629925158 GO:0033192 calmodulin-dependent protein phosphatase activity 9/1709 81/18639 0.111111111111111 1.21181977764775 0.323837188546736 0.70835629925158 GO:0140791 histone H2AXS140 phosphatase activity 9/1709 81/18639 0.111111111111111 1.21181977764775 0.323837188546736 0.70835629925158 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 9/1709 81/18639 0.111111111111111 1.21181977764775 0.323837188546736 0.70835629925158 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 9/1709 81/18639 0.111111111111111 1.21181977764775 0.323837188546736 0.70835629925158 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 9/1709 81/18639 0.111111111111111 1.21181977764775 0.323837188546736 0.70835629925158 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 9/1709 81/18639 0.111111111111111 1.21181977764775 0.323837188546736 0.70835629925158 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 9/1709 81/18639 0.111111111111111 1.21181977764775 0.323837188546736 0.70835629925158 GO:1990439 MAP kinase serine/threonine phosphatase activity 9/1709 81/18639 0.111111111111111 1.21181977764775 0.323837188546736 0.70835629925158 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 13/1709 122/18639 0.10655737704918 1.16215503266218 0.32694365877758 0.712133458317539 GO:0008237 metallopeptidase activity 19/1709 184/18639 0.103260869565217 1.12620207596611 0.327689418083057 0.712133458317539 GO:0031683 G-protein beta/gamma-subunit complex binding 3/1709 22/18639 0.136363636363636 1.48723336347678 0.327980040599172 0.712133458317539 GO:0140035 ubiquitin-like protein reader activity 3/1709 22/18639 0.136363636363636 1.48723336347678 0.327980040599172 0.712133458317539 GO:0140713 histone chaperone activity 17/1709 164/18639 0.103658536585366 1.13053918280552 0.334331482557714 0.723825698885303 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 9/1709 82/18639 0.109756097560976 1.19704148767643 0.337025069588525 0.723825698885303 GO:0033549 MAP kinase phosphatase activity 9/1709 82/18639 0.109756097560976 1.19704148767643 0.337025069588525 0.723825698885303 GO:0005172 vascular endothelial growth factor receptor binding 2/1709 13/18639 0.153846153846154 1.67790430751227 0.337662539768377 0.723825698885303 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 2/1709 13/18639 0.153846153846154 1.67790430751227 0.337662539768377 0.723825698885303 GO:0070700 BMP receptor binding 2/1709 13/18639 0.153846153846154 1.67790430751227 0.337662539768377 0.723825698885303 GO:0140333 glycerophospholipid flippase activity 2/1709 13/18639 0.153846153846154 1.67790430751227 0.337662539768377 0.723825698885303 GO:0016859 cis-trans isomerase activity 5/1709 42/18639 0.119047619047619 1.29837833319401 0.340430355604919 0.725799980575407 GO:0019894 kinesin binding 5/1709 42/18639 0.119047619047619 1.29837833319401 0.340430355604919 0.725799980575407 GO:0035198 miRNA binding 5/1709 42/18639 0.119047619047619 1.29837833319401 0.340430355604919 0.725799980575407 GO:0004842 ubiquitin-protein transferase activity 44/1709 449/18639 0.0979955456570156 1.06877646313699 0.343079372751821 0.730127401578333 GO:0004722 protein serine/threonine phosphatase activity 11/1709 103/18639 0.106796116504854 1.164758815409 0.344065129797635 0.730905924380921 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 9/1709 83/18639 0.108433734939759 1.18261930107792 0.350299921126415 0.742670468590246 GO:0015399 primary active transmembrane transporter activity 17/1709 166/18639 0.102409638554217 1.11691822879582 0.352981609960845 0.742670468590246 GO:0003887 DNA-directed DNA polymerase activity 3/1709 23/18639 0.130434782608696 1.42257104332562 0.354012555850482 0.742670468590246 GO:0005158 insulin receptor binding 3/1709 23/18639 0.130434782608696 1.42257104332562 0.354012555850482 0.742670468590246 GO:0016849 phosphorus-oxygen lyase activity 3/1709 23/18639 0.130434782608696 1.42257104332562 0.354012555850482 0.742670468590246 GO:0031681 G-protein beta-subunit binding 3/1709 23/18639 0.130434782608696 1.42257104332562 0.354012555850482 0.742670468590246 GO:0099186 structural constituent of postsynapse 3/1709 23/18639 0.130434782608696 1.42257104332562 0.354012555850482 0.742670468590246 GO:0004864 protein phosphatase inhibitor activity 6/1709 53/18639 0.113207547169811 1.23468430175431 0.357998345426264 0.74826888946153 GO:0140416 transcription regulator inhibitor activity 4/1709 33/18639 0.121212121212121 1.32198521197936 0.358636762917462 0.74826888946153 GO:0004712 protein serine/threonine/tyrosine kinase activity 5/1709 43/18639 0.116279069767442 1.26818348823601 0.359219840063805 0.74826888946153 GO:0008200 ion channel inhibitor activity 5/1709 43/18639 0.116279069767442 1.26818348823601 0.359219840063805 0.74826888946153 GO:0101005 deubiquitinase activity 12/1709 115/18639 0.104347826086957 1.13805683466049 0.36354676540886 0.754819176999517 GO:0017018 myosin phosphatase activity 9/1709 84/18639 0.107142857142857 1.16854049987461 0.363644862201634 0.754819176999517 GO:0019838 growth factor binding 14/1709 136/18639 0.102941176470588 1.12271538223247 0.365689124904862 0.757728432799354 GO:0005545 1-phosphatidylinositol binding 2/1709 14/18639 0.142857142857143 1.55805399983282 0.372142571990706 0.75778254296553 GO:0008474 palmitoyl-(protein) hydrolase activity 2/1709 14/18639 0.142857142857143 1.55805399983282 0.372142571990706 0.75778254296553 GO:0031404 chloride ion binding 2/1709 14/18639 0.142857142857143 1.55805399983282 0.372142571990706 0.75778254296553 GO:0032036 myosin heavy chain binding 2/1709 14/18639 0.142857142857143 1.55805399983282 0.372142571990706 0.75778254296553 GO:0032454 histone H3K9 demethylase activity 2/1709 14/18639 0.142857142857143 1.55805399983282 0.372142571990706 0.75778254296553 GO:0042043 neurexin family protein binding 2/1709 14/18639 0.142857142857143 1.55805399983282 0.372142571990706 0.75778254296553 GO:0071933 Arp2/3 complex binding 2/1709 14/18639 0.142857142857143 1.55805399983282 0.372142571990706 0.75778254296553 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 2/1709 14/18639 0.142857142857143 1.55805399983282 0.372142571990706 0.75778254296553 GO:0098599 palmitoyl hydrolase activity 2/1709 14/18639 0.142857142857143 1.55805399983282 0.372142571990706 0.75778254296553 GO:0098847 sequence-specific single stranded DNA binding 2/1709 14/18639 0.142857142857143 1.55805399983282 0.372142571990706 0.75778254296553 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 6/1709 54/18639 0.111111111111111 1.21181977764775 0.374887019150525 0.760448044789612 GO:0050661 NADP binding 6/1709 54/18639 0.111111111111111 1.21181977764775 0.374887019150525 0.760448044789612 GO:0140658 ATP-dependent chromatin remodeler activity 16/1709 158/18639 0.10126582278481 1.10444334165364 0.376589249257683 0.760448044789612 GO:0016248 channel inhibitor activity 5/1709 44/18639 0.113636363636364 1.23936113623065 0.378038134008488 0.760448044789612 GO:0043014 alpha-tubulin binding 5/1709 44/18639 0.113636363636364 1.23936113623065 0.378038134008488 0.760448044789612 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 3/1709 24/18639 0.125 1.36329724985372 0.379911491115313 0.760448044789612 GO:0030215 semaphorin receptor binding 3/1709 24/18639 0.125 1.36329724985372 0.379911491115313 0.760448044789612 GO:0030552 cAMP binding 3/1709 24/18639 0.125 1.36329724985372 0.379911491115313 0.760448044789612 GO:0015035 protein-disulfide reductase activity 4/1709 34/18639 0.117647058823529 1.28310329397997 0.380192900489606 0.760448044789612 GO:0030332 cyclin binding 4/1709 34/18639 0.117647058823529 1.28310329397997 0.380192900489606 0.760448044789612 GO:0019783 ubiquitin-like protein peptidase activity 13/1709 127/18639 0.102362204724409 1.116400897518 0.381191513545938 0.760448044789612 GO:0042826 histone deacetylase binding 13/1709 127/18639 0.102362204724409 1.116400897518 0.381191513545938 0.760448044789612 GO:0008374 O-acyltransferase activity 6/1709 55/18639 0.109090909090909 1.18978669078142 0.391793552123573 0.778964606672513 GO:0061659 ubiquitin-like protein ligase activity 36/1709 372/18639 0.0967741935483871 1.05545593537062 0.391794751278032 0.778964606672513 GO:0140566 histone reader activity 4/1709 35/18639 0.114285714285714 1.24644319986625 0.401668495237729 0.788340579460032 GO:0008081 phosphoric diester hydrolase activity 9/1709 87/18639 0.103448275862069 1.12824599987894 0.403934202461034 0.788340579460032 GO:0001848 complement binding 3/1709 25/18639 0.12 1.30876535985957 0.405575550679772 0.788340579460032 GO:0008139 nuclear localization sequence binding 3/1709 25/18639 0.12 1.30876535985957 0.405575550679772 0.788340579460032 GO:0015645 fatty acid ligase activity 3/1709 25/18639 0.12 1.30876535985957 0.405575550679772 0.788340579460032 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 3/1709 25/18639 0.12 1.30876535985957 0.405575550679772 0.788340579460032 GO:0120515 fatty acid-CoA ligase activity 3/1709 25/18639 0.12 1.30876535985957 0.405575550679772 0.788340579460032 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/1709 15/18639 0.133333333333333 1.4541837331773 0.405871697822086 0.788340579460032 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/1709 15/18639 0.133333333333333 1.4541837331773 0.405871697822086 0.788340579460032 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/1709 15/18639 0.133333333333333 1.4541837331773 0.405871697822086 0.788340579460032 GO:0005041 low-density lipoprotein particle receptor activity 2/1709 15/18639 0.133333333333333 1.4541837331773 0.405871697822086 0.788340579460032 GO:0033130 acetylcholine receptor binding 2/1709 15/18639 0.133333333333333 1.4541837331773 0.405871697822086 0.788340579460032 GO:0042809 nuclear vitamin D receptor binding 2/1709 15/18639 0.133333333333333 1.4541837331773 0.405871697822086 0.788340579460032 GO:0120283 protein serine/threonine kinase binding 2/1709 15/18639 0.133333333333333 1.4541837331773 0.405871697822086 0.788340579460032 GO:0003724 RNA helicase activity 8/1709 77/18639 0.103896103896104 1.13313018169659 0.410555506063805 0.793992200894543 GO:0000510 H3-H4 histone complex chaperone activity 15/1709 151/18639 0.0993377483443709 1.08341503299633 0.412148623365107 0.793992200894543 GO:0140584 chromatin extrusion motor activity 15/1709 151/18639 0.0993377483443709 1.08341503299633 0.412148623365107 0.793992200894543 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 15/1709 151/18639 0.0993377483443709 1.08341503299633 0.412148623365107 0.793992200894543 GO:0140849 ATP-dependent H2AZ histone chaperone activity 15/1709 151/18639 0.0993377483443709 1.08341503299633 0.412148623365107 0.793992200894543 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 5/1709 46/18639 0.108695652173913 1.18547586943801 0.415587736635787 0.798009676699663 GO:0030276 clathrin binding 5/1709 46/18639 0.108695652173913 1.18547586943801 0.415587736635787 0.798009676699663 GO:0015616 DNA translocase activity 15/1709 152/18639 0.0986842105263158 1.07628730251609 0.422381850359999 0.80961458755954 GO:0044390 ubiquitin-like protein conjugating enzyme binding 4/1709 36/18639 0.111111111111111 1.21181977764775 0.423004737859777 0.80961458755954 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/1709 26/18639 0.115384615384615 1.2584282306342 0.430914584828675 0.810413699102321 GO:0005112 Notch binding 3/1709 26/18639 0.115384615384615 1.2584282306342 0.430914584828675 0.810413699102321 GO:0030507 spectrin binding 3/1709 26/18639 0.115384615384615 1.2584282306342 0.430914584828675 0.810413699102321 GO:0034237 protein kinase A regulatory subunit binding 3/1709 26/18639 0.115384615384615 1.2584282306342 0.430914584828675 0.810413699102321 GO:0120014 phospholipid transfer activity 3/1709 26/18639 0.115384615384615 1.2584282306342 0.430914584828675 0.810413699102321 GO:0061775 cohesin loader activity 15/1709 153/18639 0.0980392156862745 1.06925274498331 0.432620412162001 0.810413699102321 GO:0005548 phospholipid transporter activity 7/1709 68/18639 0.102941176470588 1.12271538223247 0.43314300204794 0.810413699102321 GO:0061733 protein-lysine-acetyltransferase activity 5/1709 47/18639 0.106382978723404 1.16025297859891 0.434237812384663 0.810413699102321 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 13/1709 132/18639 0.0984848484848485 1.07411298473323 0.436311150456311 0.810413699102321 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 2/1709 16/18639 0.125 1.36329724985372 0.438697753009486 0.810413699102321 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/1709 16/18639 0.125 1.36329724985372 0.438697753009486 0.810413699102321 GO:0004708 MAP kinase kinase activity 2/1709 16/18639 0.125 1.36329724985372 0.438697753009486 0.810413699102321 GO:0016722 oxidoreductase activity, acting on metal ions 2/1709 16/18639 0.125 1.36329724985372 0.438697753009486 0.810413699102321 GO:0019841 retinol binding 2/1709 16/18639 0.125 1.36329724985372 0.438697753009486 0.810413699102321 GO:0022858 alanine transmembrane transporter activity 2/1709 16/18639 0.125 1.36329724985372 0.438697753009486 0.810413699102321 GO:0030275 LRR domain binding 2/1709 16/18639 0.125 1.36329724985372 0.438697753009486 0.810413699102321 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1709 16/18639 0.125 1.36329724985372 0.438697753009486 0.810413699102321 GO:0055102 lipase inhibitor activity 2/1709 16/18639 0.125 1.36329724985372 0.438697753009486 0.810413699102321 GO:0097027 ubiquitin-protein transferase activator activity 2/1709 16/18639 0.125 1.36329724985372 0.438697753009486 0.810413699102321 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/1709 16/18639 0.125 1.36329724985372 0.438697753009486 0.810413699102321 GO:0140327 flippase activity 2/1709 16/18639 0.125 1.36329724985372 0.438697753009486 0.810413699102321 GO:0140328 floppase activity 2/1709 16/18639 0.125 1.36329724985372 0.438697753009486 0.810413699102321 GO:0008186 ATP-dependent activity, acting on RNA 8/1709 79/18639 0.10126582278481 1.10444334165364 0.439231852185227 0.810413699102321 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 22/1709 229/18639 0.0960698689956332 1.04777430556443 0.441909653761729 0.81228413516482 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 6/1709 58/18639 0.103448275862069 1.12824599987894 0.442312480725882 0.81228413516482 GO:0061980 regulatory RNA binding 6/1709 58/18639 0.103448275862069 1.12824599987894 0.442312480725882 0.81228413516482 GO:0030551 cyclic nucleotide binding 4/1709 37/18639 0.108108108108108 1.17906789176538 0.444147358717256 0.814385281380473 GO:0008080 N-acetyltransferase activity 7/1709 69/18639 0.101449275362319 1.10644414480881 0.448517952156668 0.821122151541478 GO:0008320 protein transmembrane transporter activity 3/1709 27/18639 0.111111111111111 1.21181977764775 0.455849180964986 0.830674164385963 GO:0016405 CoA-ligase activity 3/1709 27/18639 0.111111111111111 1.21181977764775 0.455849180964986 0.830674164385963 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/1709 27/18639 0.111111111111111 1.21181977764775 0.455849180964986 0.830674164385963 GO:0043021 ribonucleoprotein complex binding 17/1709 177/18639 0.096045197740113 1.04750523152602 0.45785942272335 0.831256928157139 GO:0001786 phosphatidylserine binding 6/1709 59/18639 0.101694915254237 1.10912318632167 0.458989194427733 0.831256928157139 GO:0070063 RNA polymerase binding 6/1709 59/18639 0.101694915254237 1.10912318632167 0.458989194427733 0.831256928157139 GO:0070888 E-box binding 6/1709 59/18639 0.101694915254237 1.10912318632167 0.458989194427733 0.831256928157139 GO:0140597 protein carrier chaperone 18/1709 188/18639 0.0957446808510638 1.04422768073902 0.459969725527236 0.831755071160447 GO:0004550 nucleoside diphosphate kinase activity 2/1709 17/18639 0.117647058823529 1.28310329397997 0.470502756832002 0.843862149681191 GO:0008484 sulfuric ester hydrolase activity 2/1709 17/18639 0.117647058823529 1.28310329397997 0.470502756832002 0.843862149681191 GO:0032183 SUMO binding 2/1709 17/18639 0.117647058823529 1.28310329397997 0.470502756832002 0.843862149681191 GO:0051787 misfolded protein binding 2/1709 17/18639 0.117647058823529 1.28310329397997 0.470502756832002 0.843862149681191 GO:0070402 NADPH binding 2/1709 17/18639 0.117647058823529 1.28310329397997 0.470502756832002 0.843862149681191 GO:0016829 lyase activity 19/1709 200/18639 0.095 1.03610590988882 0.470959537311471 0.843862149681191 GO:0016779 nucleotidyltransferase activity 13/1709 136/18639 0.0955882352941176 1.04252142635872 0.480301740591454 0.858008611972333 GO:0019789 SUMO transferase activity 3/1709 28/18639 0.107142857142857 1.16854049987461 0.480310164462884 0.858008611972333 GO:0015085 calcium ion transmembrane transporter activity 14/1709 147/18639 0.0952380952380952 1.03870266655521 0.482055015333932 0.859822788318769 GO:0000900 mRNA regulatory element binding translation repressor activity 2/1709 18/18639 0.111111111111111 1.21181977764775 0.501197928786491 0.888590012089132 GO:0070064 proline-rich region binding 2/1709 18/18639 0.111111111111111 1.21181977764775 0.501197928786491 0.888590012089132 GO:0099602 neurotransmitter receptor regulator activity 2/1709 18/18639 0.111111111111111 1.21181977764775 0.501197928786491 0.888590012089132 GO:1901611 phosphatidylglycerol binding 2/1709 18/18639 0.111111111111111 1.21181977764775 0.501197928786491 0.888590012089132 GO:0003689 DNA clamp loader activity 15/1709 160/18639 0.09375 1.02247293739029 0.503878478138155 0.892001089677004 GO:0004532 RNA exonuclease activity 4/1709 40/18639 0.1 1.09063779988297 0.505939042331871 0.892967261840234 GO:0050997 quaternary ammonium group binding 4/1709 40/18639 0.1 1.09063779988297 0.505939042331871 0.892967261840234 GO:0003714 transcription corepressor activity 19/1709 204/18639 0.0931372549019608 1.01579010773414 0.506873357616151 0.893279056247297 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 12/1709 128/18639 0.09375 1.02247293739029 0.512341458937612 0.90156802998126 GO:0046982 protein heterodimerization activity 34/1709 369/18639 0.0921409214092141 1.00492371804935 0.514708831623758 0.904384072256947 GO:0001727 lipid kinase activity 4/1709 41/18639 0.0975609756097561 1.06403687793461 0.52585509536629 0.910797803700771 GO:0140318 protein transporter activity 4/1709 41/18639 0.0975609756097561 1.06403687793461 0.52585509536629 0.910797803700771 GO:0140828 metal cation:monoatomic cation antiporter activity 4/1709 41/18639 0.0975609756097561 1.06403687793461 0.52585509536629 0.910797803700771 GO:0015215 nucleotide transmembrane transporter activity 3/1709 30/18639 0.1 1.09063779988297 0.527582365476288 0.910797803700771 GO:0031210 phosphatidylcholine binding 3/1709 30/18639 0.1 1.09063779988297 0.527582365476288 0.910797803700771 GO:0031624 ubiquitin conjugating enzyme binding 3/1709 30/18639 0.1 1.09063779988297 0.527582365476288 0.910797803700771 GO:0051721 protein phosphatase 2A binding 3/1709 30/18639 0.1 1.09063779988297 0.527582365476288 0.910797803700771 GO:0098918 structural constituent of synapse 3/1709 30/18639 0.1 1.09063779988297 0.527582365476288 0.910797803700771 GO:0003756 protein disulfide isomerase activity 2/1709 19/18639 0.105263157894737 1.1480397893505 0.530719330909609 0.910797803700771 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/1709 19/18639 0.105263157894737 1.1480397893505 0.530719330909609 0.910797803700771 GO:0015245 fatty acid transmembrane transporter activity 2/1709 19/18639 0.105263157894737 1.1480397893505 0.530719330909609 0.910797803700771 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/1709 19/18639 0.105263157894737 1.1480397893505 0.530719330909609 0.910797803700771 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/1709 19/18639 0.105263157894737 1.1480397893505 0.530719330909609 0.910797803700771 GO:0016918 retinal binding 2/1709 19/18639 0.105263157894737 1.1480397893505 0.530719330909609 0.910797803700771 GO:0046624 sphingolipid transporter activity 2/1709 19/18639 0.105263157894737 1.1480397893505 0.530719330909609 0.910797803700771 GO:0140036 ubiquitin-modified protein reader activity 2/1709 19/18639 0.105263157894737 1.1480397893505 0.530719330909609 0.910797803700771 GO:0015078 proton transmembrane transporter activity 17/1709 185/18639 0.0918918918918919 1.00220770800057 0.533589190929609 0.914391942014549 GO:0004843 cysteine-type deubiquitinase activity 10/1709 108/18639 0.0925925925925926 1.00984981470646 0.535632033201203 0.916560474810187 GO:0050660 flavin adenine dinucleotide binding 8/1709 86/18639 0.0930232558139535 1.01454679058881 0.537242705588556 0.917984275201315 GO:0034212 protein N-acetyltransferase activity 5/1709 53/18639 0.0943396226415094 1.02890358479526 0.542207787820118 0.925127325383385 GO:0043175 RNA polymerase core enzyme binding 4/1709 42/18639 0.0952380952380952 1.03870266655521 0.545373489025382 0.928367444505248 GO:0005262 calcium channel activity 12/1709 131/18639 0.0916030534351145 0.999057526610357 0.545681627686291 0.928367444505248 GO:0042626 ATPase-coupled transmembrane transporter activity 9/1709 98/18639 0.0918367346938776 1.00160614274967 0.549064613068361 0.932191198349195 GO:0005539 glycosaminoglycan binding 22/1709 242/18639 0.0909090909090909 0.99148890898452 0.549764465968071 0.932191198349195 GO:0016878 acid-thiol ligase activity 3/1709 31/18639 0.0967741935483871 1.05545593537062 0.550301165437693 0.932191198349195 GO:0061630 ubiquitin protein ligase activity 32/1709 353/18639 0.0906515580736544 0.988680158534139 0.554619509012265 0.938158394728064 GO:0160215 deacylase activity 6/1709 65/18639 0.0923076923076923 1.00674258450736 0.555603341801082 0.938476131781483 GO:0051082 unfolded protein binding 11/1709 121/18639 0.0909090909090909 0.99148890898452 0.558013931352227 0.941199463611267 GO:0000339 RNA cap binding 2/1709 20/18639 0.1 1.09063779988297 0.559024063001916 0.941556243256084 GO:0008375 acetylglucosaminyltransferase activity 4/1709 43/18639 0.0930232558139535 1.01454679058881 0.564466170970159 0.949366070718713 GO:0022884 macromolecule transmembrane transporter activity 3/1709 32/18639 0.09375 1.02247293739029 0.572360249897802 0.958540816235097 GO:0030515 snoRNA binding 3/1709 32/18639 0.09375 1.02247293739029 0.572360249897802 0.958540816235097 GO:0031369 translation initiation factor binding 3/1709 32/18639 0.09375 1.02247293739029 0.572360249897802 0.958540816235097 GO:0098632 cell-cell adhesion mediator activity 5/1709 55/18639 0.0909090909090909 0.99148890898452 0.576030113995544 0.959738149811292 GO:0001223 transcription coactivator binding 4/1709 44/18639 0.0909090909090909 0.99148890898452 0.583108974666326 0.959738149811292 GO:0016790 thiolester hydrolase activity 4/1709 44/18639 0.0909090909090909 0.99148890898452 0.583108974666326 0.959738149811292 GO:0043022 ribosome binding 10/1709 112/18639 0.0892857142857143 0.973783749895511 0.583190564090228 0.959738149811292 GO:0035613 RNA stem-loop binding 2/1709 21/18639 0.0952380952380952 1.03870266655521 0.586086946086547 0.959738149811292 GO:0051428 peptide hormone receptor binding 2/1709 21/18639 0.0952380952380952 1.03870266655521 0.586086946086547 0.959738149811292 GO:0061891 calcium ion sensor activity 2/1709 21/18639 0.0952380952380952 1.03870266655521 0.586086946086547 0.959738149811292 GO:0030170 pyridoxal phosphate binding 5/1709 56/18639 0.0892857142857143 0.973783749895511 0.592436347717567 0.959738149811292 GO:0016835 carbon-oxygen lyase activity 7/1709 79/18639 0.0886075949367089 0.966387923946938 0.594902473023663 0.959738149811292 GO:0051539 4 iron, 4 sulfur cluster binding 4/1709 45/18639 0.0888888888888889 0.969455822118198 0.601281425947936 0.959738149811292 GO:0140303 intramembrane lipid transporter activity 4/1709 45/18639 0.0888888888888889 0.969455822118198 0.601281425947936 0.959738149811292 GO:0070279 vitamin B6 binding 5/1709 57/18639 0.087719298245614 0.956699824458748 0.60848447882961 0.959738149811292 GO:0008970 phospholipase A1 activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0032931 histone H3K56 acetyltransferase activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0043992 histone H3K9 acetyltransferase activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0043993 histone H3K18 acetyltransferase activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0043994 histone H3K23 acetyltransferase activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0043999 histone H2AK5 acetyltransferase activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0044012 histone H2AK9 acetyltransferase activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0044014 histone H2BK5 acetyltransferase activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0044015 histone H2BK12 acetyltransferase activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0044016 histone H3K4 acetyltransferase activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0044017 histone H3K27 acetyltransferase activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0044018 histone H3K36 acetyltransferase activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0046972 histone H4K16 acetyltransferase activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0140784 metal ion sensor activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0140908 histone H3K122 acetyltransferase activity 2/1709 22/18639 0.0909090909090909 0.99148890898452 0.611897636635284 0.959738149811292 GO:0052866 phosphatidylinositol phosphate phosphatase activity 3/1709 34/18639 0.0882352941176471 0.962327470484976 0.614397730670632 0.959738149811292 GO:0090482 vitamin transmembrane transporter activity 3/1709 34/18639 0.0882352941176471 0.962327470484976 0.614397730670632 0.959738149811292 GO:0052689 carboxylic ester hydrolase activity 8/1709 92/18639 0.0869565217391304 0.948380695550411 0.615556728151163 0.959738149811292 GO:0000182 rDNA binding 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0003796 lysozyme activity 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0004382 GDP phosphatase activity 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0008239 dipeptidyl-peptidase activity 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0015643 toxic substance binding 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0031419 cobalamin binding 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0031434 mitogen-activated protein kinase kinase binding 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0032052 bile acid binding 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0035374 chondroitin sulfate binding 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0045322 unmethylated CpG binding 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0047429 nucleoside triphosphate diphosphatase activity 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0051864 histone H3K36 demethylase activity 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0051880 G-quadruplex DNA binding 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0070097 delta-catenin binding 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0070739 protein-glutamic acid ligase activity 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0070740 tubulin-glutamic acid ligase activity 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0098505 G-rich strand telomeric DNA binding 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:1990763 arrestin family protein binding 1/1709 10/18639 0.1 1.09063779988297 0.617846696952308 0.959738149811292 GO:0015101 organic cation transmembrane transporter activity 7/1709 81/18639 0.0864197530864197 0.942526493726025 0.621774469723052 0.963174459913494 GO:0019842 vitamin binding 13/1709 150/18639 0.0866666666666667 0.945219426565243 0.626233817152573 0.963174459913494 GO:0000175 3'-5'-RNA exonuclease activity 3/1709 35/18639 0.0857142857142857 0.934832399899691 0.634341096492467 0.963174459913494 GO:0016229 steroid dehydrogenase activity 3/1709 35/18639 0.0857142857142857 0.934832399899691 0.634341096492467 0.963174459913494 GO:0034061 DNA polymerase activity 3/1709 35/18639 0.0857142857142857 0.934832399899691 0.634341096492467 0.963174459913494 GO:0000295 adenine nucleotide transmembrane transporter activity 2/1709 23/18639 0.0869565217391304 0.948380695550411 0.636458120519551 0.963174459913494 GO:0004022 alcohol dehydrogenase (NAD+) activity 2/1709 23/18639 0.0869565217391304 0.948380695550411 0.636458120519551 0.963174459913494 GO:0044013 histone H2B acetyltransferase activity 2/1709 23/18639 0.0869565217391304 0.948380695550411 0.636458120519551 0.963174459913494 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/1709 23/18639 0.0869565217391304 0.948380695550411 0.636458120519551 0.963174459913494 GO:0140103 catalytic activity, acting on a glycoprotein 2/1709 23/18639 0.0869565217391304 0.948380695550411 0.636458120519551 0.963174459913494 GO:0003735 structural constituent of ribosome 15/1709 175/18639 0.0857142857142857 0.934832399899691 0.646784225084125 0.963174459913494 GO:0030165 PDZ domain binding 7/1709 83/18639 0.0843373493975904 0.919815011949495 0.647632998163577 0.963174459913494 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/1709 48/18639 0.0833333333333333 0.90886483323581 0.652822984780173 0.963174459913494 GO:0032266 phosphatidylinositol-3-phosphate binding 4/1709 48/18639 0.0833333333333333 0.90886483323581 0.652822984780173 0.963174459913494 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0002162 dystroglycan binding 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0005225 volume-sensitive anion channel activity 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0008172 S-methyltransferase activity 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0008432 JUN kinase binding 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0008503 benzodiazepine receptor activity 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0015217 ADP transmembrane transporter activity 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0032050 clathrin heavy chain binding 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0032794 GTPase activating protein binding 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0034511 U3 snoRNA binding 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0045294 alpha-catenin binding 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0048185 activin binding 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0070990 snRNP binding 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0180030 inositol phosphate kinase activity 1/1709 11/18639 0.0909090909090909 0.99148890898452 0.652904939204092 0.963174459913494 GO:0000993 RNA polymerase II complex binding 3/1709 36/18639 0.0833333333333333 0.90886483323581 0.653553492731802 0.963174459913494 GO:0045505 dynein intermediate chain binding 3/1709 36/18639 0.0833333333333333 0.90886483323581 0.653553492731802 0.963174459913494 GO:0055106 ubiquitin-protein transferase regulator activity 3/1709 36/18639 0.0833333333333333 0.90886483323581 0.653553492731802 0.963174459913494 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/1709 36/18639 0.0833333333333333 0.90886483323581 0.653553492731802 0.963174459913494 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/1709 36/18639 0.0833333333333333 0.90886483323581 0.653553492731802 0.963174459913494 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/1709 36/18639 0.0833333333333333 0.90886483323581 0.653553492731802 0.963174459913494 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/1709 24/18639 0.0833333333333333 0.90886483323581 0.659780541374482 0.965692236700744 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/1709 24/18639 0.0833333333333333 0.90886483323581 0.659780541374482 0.965692236700744 GO:0005315 phosphate transmembrane transporter activity 2/1709 24/18639 0.0833333333333333 0.90886483323581 0.659780541374482 0.965692236700744 GO:0043998 histone H2A acetyltransferase activity 2/1709 24/18639 0.0833333333333333 0.90886483323581 0.659780541374482 0.965692236700744 GO:0070840 dynein complex binding 2/1709 24/18639 0.0833333333333333 0.90886483323581 0.659780541374482 0.965692236700744 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 5/1709 61/18639 0.0819672131147541 0.893965409740141 0.668857530200258 0.965692236700744 GO:0016836 hydro-lyase activity 5/1709 61/18639 0.0819672131147541 0.893965409740141 0.668857530200258 0.965692236700744 GO:0004386 helicase activity 13/1709 155/18639 0.0838709677419355 0.914728477321203 0.673176048532786 0.965692236700744 GO:0003707 nuclear steroid receptor activity 2/1709 25/18639 0.08 0.872510239906378 0.681885323174022 0.965692236700744 GO:0005251 delayed rectifier potassium channel activity 2/1709 25/18639 0.08 0.872510239906378 0.681885323174022 0.965692236700744 GO:0120020 cholesterol transfer activity 2/1709 25/18639 0.08 0.872510239906378 0.681885323174022 0.965692236700744 GO:0035064 methylated histone binding 6/1709 74/18639 0.0810810810810811 0.884300918824032 0.683145439331537 0.965692236700744 GO:0015605 organophosphate ester transmembrane transporter activity 4/1709 50/18639 0.08 0.872510239906378 0.684604122965697 0.965692236700744 GO:0000340 RNA 7-methylguanosine cap binding 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0004032 aldose reductase (NADPH) activity 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0004300 enoyl-CoA hydratase activity 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0005025 transforming growth factor beta receptor activity, type I 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0005026 transforming growth factor beta receptor activity, type II 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0005049 nuclear export signal receptor activity 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0005095 GTPase inhibitor activity 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0005165 neurotrophin receptor binding 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0015132 prostaglandin transmembrane transporter activity 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0015166 polyol transmembrane transporter activity 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0016361 activin receptor activity, type I 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0016362 activin receptor activity, type II 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0016423 tRNA (guanine) methyltransferase activity 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0017002 activin receptor activity 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0017166 vinculin binding 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0035197 siRNA binding 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0043047 single-stranded telomeric DNA binding 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0070410 co-SMAD binding 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0140900 chloride:bicarbonate antiporter activity 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:1990459 transferrin receptor binding 1/1709 12/18639 0.0833333333333333 0.90886483323581 0.684748693708076 0.965692236700744 GO:0000146 microfilament motor activity 3/1709 38/18639 0.0789473684210526 0.861029842012873 0.689771977664431 0.970454846857236 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 3/1709 38/18639 0.0789473684210526 0.861029842012873 0.689771977664431 0.970454846857236 GO:0044183 protein folding chaperone 6/1709 75/18639 0.08 0.872510239906378 0.695729362684181 0.977669748038914 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 15/1709 181/18639 0.0828729281767956 0.903843480565999 0.697553043635191 0.979065521959393 GO:0005048 signal sequence binding 4/1709 51/18639 0.0784313725490196 0.855402195986645 0.699704983290774 0.979433417334045 GO:0015216 purine nucleotide transmembrane transporter activity 2/1709 26/18639 0.0769230769230769 0.838952153756133 0.702799551369468 0.979433417334045 GO:0050750 low-density lipoprotein particle receptor binding 2/1709 26/18639 0.0769230769230769 0.838952153756133 0.702799551369468 0.979433417334045 GO:0051139 metal cation:proton antiporter activity 2/1709 26/18639 0.0769230769230769 0.838952153756133 0.702799551369468 0.979433417334045 GO:0052742 phosphatidylinositol kinase activity 2/1709 26/18639 0.0769230769230769 0.838952153756133 0.702799551369468 0.979433417334045 GO:0097602 cullin family protein binding 2/1709 26/18639 0.0769230769230769 0.838952153756133 0.702799551369468 0.979433417334045 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/1709 39/18639 0.0769230769230769 0.838952153756133 0.70678152187942 0.979534254372988 GO:0140034 methylation-dependent protein binding 6/1709 76/18639 0.0789473684210526 0.861029842012873 0.707975272489387 0.979534254372988 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1709 13/18639 0.0769230769230769 0.838952153756133 0.713672539869718 0.979534254372988 GO:0004465 lipoprotein lipase activity 1/1709 13/18639 0.0769230769230769 0.838952153756133 0.713672539869718 0.979534254372988 GO:0008035 high-density lipoprotein particle binding 1/1709 13/18639 0.0769230769230769 0.838952153756133 0.713672539869718 0.979534254372988 GO:0019104 DNA N-glycosylase activity 1/1709 13/18639 0.0769230769230769 0.838952153756133 0.713672539869718 0.979534254372988 GO:0031994 insulin-like growth factor I binding 1/1709 13/18639 0.0769230769230769 0.838952153756133 0.713672539869718 0.979534254372988 GO:0039706 co-receptor binding 1/1709 13/18639 0.0769230769230769 0.838952153756133 0.713672539869718 0.979534254372988 GO:0051011 microtubule minus-end binding 1/1709 13/18639 0.0769230769230769 0.838952153756133 0.713672539869718 0.979534254372988 GO:0061459 L-arginine transmembrane transporter activity 1/1709 13/18639 0.0769230769230769 0.838952153756133 0.713672539869718 0.979534254372988 GO:0070123 transforming growth factor beta receptor activity, type III 1/1709 13/18639 0.0769230769230769 0.838952153756133 0.713672539869718 0.979534254372988 GO:0071714 icosanoid transmembrane transporter activity 1/1709 13/18639 0.0769230769230769 0.838952153756133 0.713672539869718 0.979534254372988 GO:0140666 annealing activity 1/1709 13/18639 0.0769230769230769 0.838952153756133 0.713672539869718 0.979534254372988 GO:0008395 steroid hydroxylase activity 2/1709 27/18639 0.0740740740740741 0.807879851765165 0.722555581001826 0.985961846398187 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/1709 27/18639 0.0740740740740741 0.807879851765165 0.722555581001826 0.985961846398187 GO:0019843 rRNA binding 5/1709 65/18639 0.0769230769230769 0.838952153756133 0.722770763753455 0.985961846398187 GO:0120013 lipid transfer activity 5/1709 65/18639 0.0769230769230769 0.838952153756133 0.722770763753455 0.985961846398187 GO:0071855 neuropeptide receptor binding 3/1709 40/18639 0.075 0.817978349912229 0.72306604724814 0.985961846398187 GO:0016860 intramolecular oxidoreductase activity 4/1709 53/18639 0.0754716981132075 0.823122867836206 0.728324479812041 0.985961846398187 GO:0008137 NADH dehydrogenase (ubiquinone) activity 3/1709 41/18639 0.0731707317073171 0.798027658450955 0.738635332923023 0.985961846398187 GO:0016877 ligase activity, forming carbon-sulfur bonds 3/1709 41/18639 0.0731707317073171 0.798027658450955 0.738635332923023 0.985961846398187 GO:0004065 arylsulfatase activity 1/1709 14/18639 0.0714285714285714 0.779026999916409 0.739944075860411 0.985961846398187 GO:0005347 ATP transmembrane transporter activity 1/1709 14/18639 0.0714285714285714 0.779026999916409 0.739944075860411 0.985961846398187 GO:0008331 high voltage-gated calcium channel activity 1/1709 14/18639 0.0714285714285714 0.779026999916409 0.739944075860411 0.985961846398187 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/1709 14/18639 0.0714285714285714 0.779026999916409 0.739944075860411 0.985961846398187 GO:0019992 diacylglycerol binding 1/1709 14/18639 0.0714285714285714 0.779026999916409 0.739944075860411 0.985961846398187 GO:0043176 amine binding 1/1709 14/18639 0.0714285714285714 0.779026999916409 0.739944075860411 0.985961846398187 GO:0061665 SUMO ligase activity 1/1709 14/18639 0.0714285714285714 0.779026999916409 0.739944075860411 0.985961846398187 GO:0061783 peptidoglycan muralytic activity 1/1709 14/18639 0.0714285714285714 0.779026999916409 0.739944075860411 0.985961846398187 GO:0070742 C2H2 zinc finger domain binding 1/1709 14/18639 0.0714285714285714 0.779026999916409 0.739944075860411 0.985961846398187 GO:0098821 BMP receptor activity 1/1709 14/18639 0.0714285714285714 0.779026999916409 0.739944075860411 0.985961846398187 GO:1901474 azole transmembrane transporter activity 1/1709 14/18639 0.0714285714285714 0.779026999916409 0.739944075860411 0.985961846398187 GO:1901612 cardiolipin binding 1/1709 14/18639 0.0714285714285714 0.779026999916409 0.739944075860411 0.985961846398187 GO:1990825 sequence-specific mRNA binding 1/1709 14/18639 0.0714285714285714 0.779026999916409 0.739944075860411 0.985961846398187 GO:0008094 ATP-dependent activity, acting on DNA 17/1709 210/18639 0.080952380952381 0.88289726657193 0.740268124055424 0.985961846398187 GO:0008527 taste receptor activity 2/1709 28/18639 0.0714285714285714 0.779026999916409 0.741189843812514 0.985961846398187 GO:0036408 histone H3K14 acetyltransferase activity 2/1709 28/18639 0.0714285714285714 0.779026999916409 0.741189843812514 0.985961846398187 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/1709 28/18639 0.0714285714285714 0.779026999916409 0.741189843812514 0.985961846398187 GO:0017069 snRNA binding 4/1709 54/18639 0.0740740740740741 0.807879851765165 0.741847931345521 0.985961846398187 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5/1709 67/18639 0.0746268656716418 0.813908805882815 0.747248593179572 0.985961846398187 GO:0050840 extracellular matrix binding 5/1709 67/18639 0.0746268656716418 0.813908805882815 0.747248593179572 0.985961846398187 GO:0043178 alcohol binding 7/1709 92/18639 0.0760869565217391 0.82983310860661 0.750238110940477 0.985961846398187 GO:0042393 histone binding 20/1709 247/18639 0.0809716599190283 0.883107530269613 0.75280078295438 0.985961846398187 GO:0004402 histone acetyltransferase activity 3/1709 42/18639 0.0714285714285714 0.779026999916409 0.753501628607457 0.985961846398187 GO:0004520 DNA endonuclease activity 3/1709 42/18639 0.0714285714285714 0.779026999916409 0.753501628607457 0.985961846398187 GO:0031492 nucleosomal DNA binding 3/1709 42/18639 0.0714285714285714 0.779026999916409 0.753501628607457 0.985961846398187 GO:0000049 tRNA binding 6/1709 80/18639 0.075 0.817978349912229 0.753549696387557 0.985961846398187 GO:0004181 metallocarboxypeptidase activity 2/1709 29/18639 0.0689655172413793 0.752163999919291 0.758741829594424 0.985961846398187 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/1709 29/18639 0.0689655172413793 0.752163999919291 0.758741829594424 0.985961846398187 GO:0010484 histone H3 acetyltransferase activity 2/1709 29/18639 0.0689655172413793 0.752163999919291 0.758741829594424 0.985961846398187 GO:0097472 cyclin-dependent protein kinase activity 2/1709 29/18639 0.0689655172413793 0.752163999919291 0.758741829594424 0.985961846398187 GO:0099604 ligand-gated calcium channel activity 2/1709 29/18639 0.0689655172413793 0.752163999919291 0.758741829594424 0.985961846398187 GO:0000774 adenyl-nucleotide exchange factor activity 1/1709 15/18639 0.0666666666666667 0.727091866588648 0.763806388577434 0.985961846398187 GO:0004559 alpha-mannosidase activity 1/1709 15/18639 0.0666666666666667 0.727091866588648 0.763806388577434 0.985961846398187 GO:0008242 omega peptidase activity 1/1709 15/18639 0.0666666666666667 0.727091866588648 0.763806388577434 0.985961846398187 GO:0015116 sulfate transmembrane transporter activity 1/1709 15/18639 0.0666666666666667 0.727091866588648 0.763806388577434 0.985961846398187 GO:0015250 water channel activity 1/1709 15/18639 0.0666666666666667 0.727091866588648 0.763806388577434 0.985961846398187 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1709 15/18639 0.0666666666666667 0.727091866588648 0.763806388577434 0.985961846398187 GO:0016846 carbon-sulfur lyase activity 1/1709 15/18639 0.0666666666666667 0.727091866588648 0.763806388577434 0.985961846398187 GO:0045504 dynein heavy chain binding 1/1709 15/18639 0.0666666666666667 0.727091866588648 0.763806388577434 0.985961846398187 GO:0050780 dopamine receptor binding 1/1709 15/18639 0.0666666666666667 0.727091866588648 0.763806388577434 0.985961846398187 GO:0061578 K63-linked deubiquitinase activity 1/1709 15/18639 0.0666666666666667 0.727091866588648 0.763806388577434 0.985961846398187 GO:0140161 monocarboxylate:sodium symporter activity 1/1709 15/18639 0.0666666666666667 0.727091866588648 0.763806388577434 0.985961846398187 GO:0141050 histone H3K deacetylase activity 1/1709 15/18639 0.0666666666666667 0.727091866588648 0.763806388577434 0.985961846398187 GO:0141051 histone H4K deacetylase activity 1/1709 15/18639 0.0666666666666667 0.727091866588648 0.763806388577434 0.985961846398187 GO:0016298 lipase activity 10/1709 130/18639 0.0769230769230769 0.838952153756133 0.763935757003175 0.985961846398187 GO:0016798 hydrolase activity, acting on glycosyl bonds 10/1709 130/18639 0.0769230769230769 0.838952153756133 0.763935757003175 0.985961846398187 GO:0005245 voltage-gated calcium channel activity 3/1709 43/18639 0.0697674418604651 0.760910092941609 0.767679287930255 0.985961846398187 GO:0016410 N-acyltransferase activity 7/1709 94/18639 0.074468085106383 0.812177085019235 0.769860925121643 0.985961846398187 GO:0042562 hormone binding 7/1709 94/18639 0.074468085106383 0.812177085019235 0.769860925121643 0.985961846398187 GO:0016769 transferase activity, transferring nitrogenous groups 2/1709 30/18639 0.0666666666666667 0.727091866588648 0.775253219888576 0.985961846398187 GO:0043995 histone H4K5 acetyltransferase activity 2/1709 30/18639 0.0666666666666667 0.727091866588648 0.775253219888576 0.985961846398187 GO:0043996 histone H4K8 acetyltransferase activity 2/1709 30/18639 0.0666666666666667 0.727091866588648 0.775253219888576 0.985961846398187 GO:0043997 histone H4K12 acetyltransferase activity 2/1709 30/18639 0.0666666666666667 0.727091866588648 0.775253219888576 0.985961846398187 GO:0048019 receptor antagonist activity 2/1709 30/18639 0.0666666666666667 0.727091866588648 0.775253219888576 0.985961846398187 GO:0016853 isomerase activity 14/1709 180/18639 0.0777777777777778 0.848273844353423 0.778205847674572 0.985961846398187 GO:0005179 hormone activity 10/1709 132/18639 0.0757575757575758 0.8262407574871 0.780103277533163 0.985961846398187 GO:0008028 monocarboxylic acid transmembrane transporter activity 5/1709 70/18639 0.0714285714285714 0.779026999916409 0.780900477070383 0.985961846398187 GO:0003954 NADH dehydrogenase activity 3/1709 44/18639 0.0681818181818182 0.74361668173839 0.781184432803225 0.985961846398187 GO:0019205 nucleobase-containing compound kinase activity 3/1709 44/18639 0.0681818181818182 0.74361668173839 0.781184432803225 0.985961846398187 GO:0000062 fatty-acyl-CoA binding 1/1709 16/18639 0.0625 0.681648624926858 0.785480297615297 0.985961846398187 GO:0005024 transforming growth factor beta receptor activity 1/1709 16/18639 0.0625 0.681648624926858 0.785480297615297 0.985961846398187 GO:0005159 insulin-like growth factor receptor binding 1/1709 16/18639 0.0625 0.681648624926858 0.785480297615297 0.985961846398187 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/1709 16/18639 0.0625 0.681648624926858 0.785480297615297 0.985961846398187 GO:0008142 oxysterol binding 1/1709 16/18639 0.0625 0.681648624926858 0.785480297615297 0.985961846398187 GO:0008296 3'-5'-DNA exonuclease activity 1/1709 16/18639 0.0625 0.681648624926858 0.785480297615297 0.985961846398187 GO:0015378 sodium:chloride symporter activity 1/1709 16/18639 0.0625 0.681648624926858 0.785480297615297 0.985961846398187 GO:0015385 sodium:proton antiporter activity 1/1709 16/18639 0.0625 0.681648624926858 0.785480297615297 0.985961846398187 GO:0015923 mannosidase activity 1/1709 16/18639 0.0625 0.681648624926858 0.785480297615297 0.985961846398187 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1709 16/18639 0.0625 0.681648624926858 0.785480297615297 0.985961846398187 GO:0017070 U6 snRNA binding 1/1709 16/18639 0.0625 0.681648624926858 0.785480297615297 0.985961846398187 GO:0003697 single-stranded DNA binding 9/1709 121/18639 0.0743801652892562 0.811218198260062 0.789985036202604 0.985961846398187 GO:0005184 neuropeptide hormone activity 2/1709 31/18639 0.0645161290322581 0.703637290247079 0.790767154678293 0.985961846398187 GO:0005452 solute:inorganic anion antiporter activity 2/1709 31/18639 0.0645161290322581 0.703637290247079 0.790767154678293 0.985961846398187 GO:0008327 methyl-CpG binding 2/1709 31/18639 0.0645161290322581 0.703637290247079 0.790767154678293 0.985961846398187 GO:0047499 calcium-independent phospholipase A2 activity 2/1709 31/18639 0.0645161290322581 0.703637290247079 0.790767154678293 0.985961846398187 GO:0070273 phosphatidylinositol-4-phosphate binding 2/1709 31/18639 0.0645161290322581 0.703637290247079 0.790767154678293 0.985961846398187 GO:0070325 lipoprotein particle receptor binding 2/1709 31/18639 0.0645161290322581 0.703637290247079 0.790767154678293 0.985961846398187 GO:0072349 modified amino acid transmembrane transporter activity 2/1709 31/18639 0.0645161290322581 0.703637290247079 0.790767154678293 0.985961846398187 GO:0140097 catalytic activity, acting on DNA 27/1709 336/18639 0.0803571428571429 0.87640537490596 0.792127725411499 0.985961846398187 GO:0004620 phospholipase activity 8/1709 109/18639 0.073394495412844 0.800468110005851 0.792971847081429 0.985961846398187 GO:0046915 transition metal ion transmembrane transporter activity 3/1709 45/18639 0.0666666666666667 0.727091866588648 0.794034647578603 0.985961846398187 GO:0016757 glycosyltransferase activity 21/1709 267/18639 0.0786516853932584 0.857805011143911 0.800355664903085 0.985961846398187 GO:0005518 collagen binding 5/1709 72/18639 0.0694444444444444 0.757387361029842 0.80134224791855 0.985961846398187 GO:0036002 pre-mRNA binding 4/1709 59/18639 0.0677966101694915 0.739415457547778 0.801840121026208 0.985961846398187 GO:0004549 tRNA-specific ribonuclease activity 1/1709 17/18639 0.0588235294117647 0.641551646989984 0.805166393914253 0.985961846398187 GO:0015278 intracellularly gated calcium channel activity 1/1709 17/18639 0.0588235294117647 0.641551646989984 0.805166393914253 0.985961846398187 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/1709 17/18639 0.0588235294117647 0.641551646989984 0.805166393914253 0.985961846398187 GO:0030548 acetylcholine receptor regulator activity 1/1709 17/18639 0.0588235294117647 0.641551646989984 0.805166393914253 0.985961846398187 GO:0032977 membrane insertase activity 1/1709 17/18639 0.0588235294117647 0.641551646989984 0.805166393914253 0.985961846398187 GO:0070403 NAD+ binding 1/1709 17/18639 0.0588235294117647 0.641551646989984 0.805166393914253 0.985961846398187 GO:1901567 fatty acid derivative binding 1/1709 17/18639 0.0588235294117647 0.641551646989984 0.805166393914253 0.985961846398187 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/1709 32/18639 0.0625 0.681648624926858 0.805327614996992 0.985961846398187 GO:0070717 poly-purine tract binding 2/1709 32/18639 0.0625 0.681648624926858 0.805327614996992 0.985961846398187 GO:0120015 sterol transfer activity 2/1709 32/18639 0.0625 0.681648624926858 0.805327614996992 0.985961846398187 GO:0140142 nucleocytoplasmic carrier activity 2/1709 32/18639 0.0625 0.681648624926858 0.805327614996992 0.985961846398187 GO:0160041 neuropeptide activity 2/1709 32/18639 0.0625 0.681648624926858 0.805327614996992 0.985961846398187 GO:0061749 forked DNA-dependent helicase activity 3/1709 47/18639 0.0638297872340425 0.696151787159344 0.817846299024688 0.992200700926802 GO:0140359 ABC-type transporter activity 3/1709 47/18639 0.0638297872340425 0.696151787159344 0.817846299024688 0.992200700926802 GO:1990518 single-stranded 3'-5' DNA helicase activity 3/1709 47/18639 0.0638297872340425 0.696151787159344 0.817846299024688 0.992200700926802 GO:0031491 nucleosome binding 5/1709 74/18639 0.0675675675675676 0.73691743235336 0.820246693464062 0.992200700926802 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/1709 18/18639 0.0555555555555556 0.605909888823874 0.823046891862945 0.992200700926802 GO:0005372 water transmembrane transporter activity 1/1709 18/18639 0.0555555555555556 0.605909888823874 0.823046891862945 0.992200700926802 GO:0015172 acidic amino acid transmembrane transporter activity 1/1709 18/18639 0.0555555555555556 0.605909888823874 0.823046891862945 0.992200700926802 GO:0015373 monoatomic anion:sodium symporter activity 1/1709 18/18639 0.0555555555555556 0.605909888823874 0.823046891862945 0.992200700926802 GO:0017128 phospholipid scramblase activity 1/1709 18/18639 0.0555555555555556 0.605909888823874 0.823046891862945 0.992200700926802 GO:0031690 adrenergic receptor binding 1/1709 18/18639 0.0555555555555556 0.605909888823874 0.823046891862945 0.992200700926802 GO:0034185 apolipoprotein binding 1/1709 18/18639 0.0555555555555556 0.605909888823874 0.823046891862945 0.992200700926802 GO:0035615 clathrin adaptor activity 1/1709 18/18639 0.0555555555555556 0.605909888823874 0.823046891862945 0.992200700926802 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/1709 18/18639 0.0555555555555556 0.605909888823874 0.823046891862945 0.992200700926802 GO:0070628 proteasome binding 1/1709 18/18639 0.0555555555555556 0.605909888823874 0.823046891862945 0.992200700926802 GO:1990381 ubiquitin-specific protease binding 1/1709 18/18639 0.0555555555555556 0.605909888823874 0.823046891862945 0.992200700926802 GO:0009378 four-way junction helicase activity 3/1709 48/18639 0.0625 0.681648624926858 0.828847853307656 0.995123848319477 GO:0036121 double-stranded DNA helicase activity 3/1709 48/18639 0.0625 0.681648624926858 0.828847853307656 0.995123848319477 GO:0043138 3'-5' DNA helicase activity 3/1709 48/18639 0.0625 0.681648624926858 0.828847853307656 0.995123848319477 GO:0140693 molecular condensate scaffold activity 3/1709 48/18639 0.0625 0.681648624926858 0.828847853307656 0.995123848319477 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/1709 34/18639 0.0588235294117647 0.641551646989984 0.831765229859404 0.997610585965654 GO:0098631 cell adhesion mediator activity 5/1709 76/18639 0.0657894736842105 0.717524868344061 0.837673571338809 0.999999999905319 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/1709 19/18639 0.0526315789473684 0.574019894675249 0.839287311915908 0.999999999905319 GO:0008301 DNA binding, bending 1/1709 19/18639 0.0526315789473684 0.574019894675249 0.839287311915908 0.999999999905319 GO:0022821 solute:potassium antiporter activity 1/1709 19/18639 0.0526315789473684 0.574019894675249 0.839287311915908 0.999999999905319 GO:0120227 acyl-CoA binding 1/1709 19/18639 0.0526315789473684 0.574019894675249 0.839287311915908 0.999999999905319 GO:1990380 K48-linked deubiquitinase activity 1/1709 19/18639 0.0526315789473684 0.574019894675249 0.839287311915908 0.999999999905319 GO:0004623 phospholipase A2 activity 2/1709 35/18639 0.0571428571428571 0.623221599933127 0.84373032885134 0.999999999905319 GO:0010485 histone H4 acetyltransferase activity 2/1709 35/18639 0.0571428571428571 0.623221599933127 0.84373032885134 0.999999999905319 GO:0004536 DNA nuclease activity 4/1709 64/18639 0.0625 0.681648624926858 0.850003536518469 0.999999999905319 GO:0072341 modified amino acid binding 6/1709 91/18639 0.0659340659340659 0.719101846076685 0.851599871845798 0.999999999905319 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/1709 20/18639 0.05 0.545318899941486 0.854038009227171 0.999999999905319 GO:0005326 neurotransmitter transmembrane transporter activity 1/1709 20/18639 0.05 0.545318899941486 0.854038009227171 0.999999999905319 GO:0015095 magnesium ion transmembrane transporter activity 1/1709 20/18639 0.05 0.545318899941486 0.854038009227171 0.999999999905319 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1709 20/18639 0.05 0.545318899941486 0.854038009227171 0.999999999905319 GO:0030627 pre-mRNA 5'-splice site binding 1/1709 20/18639 0.05 0.545318899941486 0.854038009227171 0.999999999905319 GO:0052745 inositol phosphate phosphatase activity 1/1709 20/18639 0.05 0.545318899941486 0.854038009227171 0.999999999905319 GO:0061608 nuclear import signal receptor activity 1/1709 20/18639 0.05 0.545318899941486 0.854038009227171 0.999999999905319 GO:0004190 aspartic-type endopeptidase activity 2/1709 36/18639 0.0555555555555556 0.605909888823874 0.854917201564254 0.999999999905319 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 2/1709 36/18639 0.0555555555555556 0.605909888823874 0.854917201564254 0.999999999905319 GO:0016830 carbon-carbon lyase activity 3/1709 51/18639 0.0588235294117647 0.641551646989984 0.858486966832711 0.999999999905319 GO:0019213 deacetylase activity 2/1709 37/18639 0.0540540540540541 0.589533945882688 0.865367869964691 0.999999999905319 GO:0022829 wide pore channel activity 2/1709 37/18639 0.0540540540540541 0.589533945882688 0.865367869964691 0.999999999905319 GO:0070001 aspartic-type peptidase activity 2/1709 37/18639 0.0540540540540541 0.589533945882688 0.865367869964691 0.999999999905319 GO:0010314 phosphatidylinositol-5-phosphate binding 1/1709 21/18639 0.0476190476190476 0.519351333277606 0.867435562384202 0.999999999905319 GO:0015174 basic amino acid transmembrane transporter activity 1/1709 21/18639 0.0476190476190476 0.519351333277606 0.867435562384202 0.999999999905319 GO:0140312 cargo adaptor activity 1/1709 21/18639 0.0476190476190476 0.519351333277606 0.867435562384202 0.999999999905319 GO:1904047 S-adenosyl-L-methionine binding 1/1709 21/18639 0.0476190476190476 0.519351333277606 0.867435562384202 0.999999999905319 GO:0008201 heparin binding 12/1709 172/18639 0.0697674418604651 0.760910092941609 0.874370022267052 0.999999999905319 GO:0005109 frizzled binding 2/1709 38/18639 0.0526315789473684 0.574019894675249 0.875123197314705 0.999999999905319 GO:0008146 sulfotransferase activity 3/1709 53/18639 0.0566037735849057 0.617342150877154 0.87565558778464 0.999999999905319 GO:0017046 peptide hormone binding 3/1709 53/18639 0.0566037735849057 0.617342150877154 0.87565558778464 0.999999999905319 GO:1901505 carbohydrate derivative transmembrane transporter activity 3/1709 53/18639 0.0566037735849057 0.617342150877154 0.87565558778464 0.999999999905319 GO:0004867 serine-type endopeptidase inhibitor activity 6/1709 95/18639 0.0631578947368421 0.688823873610298 0.878233797614455 0.999999999905319 GO:0004407 histone deacetylase activity 1/1709 22/18639 0.0454545454545455 0.49574445449226 0.879604035038913 0.999999999905319 GO:0008093 cytoskeletal anchor activity 1/1709 22/18639 0.0454545454545455 0.49574445449226 0.879604035038913 0.999999999905319 GO:0015377 chloride:monoatomic cation symporter activity 1/1709 22/18639 0.0454545454545455 0.49574445449226 0.879604035038913 0.999999999905319 GO:0016881 acid-amino acid ligase activity 1/1709 22/18639 0.0454545454545455 0.49574445449226 0.879604035038913 0.999999999905319 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/1709 22/18639 0.0454545454545455 0.49574445449226 0.879604035038913 0.999999999905319 GO:0033558 protein lysine deacetylase activity 1/1709 22/18639 0.0454545454545455 0.49574445449226 0.879604035038913 0.999999999905319 GO:0070034 telomerase RNA binding 1/1709 22/18639 0.0454545454545455 0.49574445449226 0.879604035038913 0.999999999905319 GO:0015297 antiporter activity 9/1709 135/18639 0.0666666666666667 0.727091866588648 0.880985679792298 0.999999999905319 GO:0004222 metalloendopeptidase activity 7/1709 110/18639 0.0636363636363636 0.694042236289164 0.887592865595063 0.999999999905319 GO:0002039 p53 binding 4/1709 69/18639 0.0579710144927536 0.632253797033607 0.887862481753165 0.999999999905319 GO:1901681 sulfur compound binding 20/1709 275/18639 0.0727272727272727 0.793191127187616 0.888444809762118 0.999999999905319 GO:0005212 structural constituent of eye lens 1/1709 23/18639 0.0434782608695652 0.474190347775205 0.89065612206252 0.999999999905319 GO:0005283 amino acid:sodium symporter activity 1/1709 23/18639 0.0434782608695652 0.474190347775205 0.89065612206252 0.999999999905319 GO:0016917 GABA receptor activity 1/1709 23/18639 0.0434782608695652 0.474190347775205 0.89065612206252 0.999999999905319 GO:0017134 fibroblast growth factor binding 1/1709 23/18639 0.0434782608695652 0.474190347775205 0.89065612206252 0.999999999905319 GO:0140662 ATP-dependent protein folding chaperone 2/1709 40/18639 0.05 0.545318899941486 0.892704678921923 0.999999999905319 GO:0016782 transferase activity, transferring sulphur-containing groups 4/1709 70/18639 0.0571428571428571 0.623221599933127 0.894345027491515 0.999999999905319 GO:0140098 catalytic activity, acting on RNA 29/1709 387/18639 0.0749354005167959 0.817273803529876 0.895814469638928 0.999999999905319 GO:0170055 lipid transmembrane transporter activity 3/1709 56/18639 0.0535714285714286 0.584270249937307 0.897946499768467 0.999999999905319 GO:0005319 lipid transporter activity 12/1709 178/18639 0.0674157303370786 0.735261438123352 0.900418488656921 0.999999999905319 GO:0140299 molecular sensor activity 4/1709 71/18639 0.0563380281690141 0.614443830919985 0.900495959186539 0.999999999905319 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/1709 41/18639 0.0487804878048781 0.532018438967304 0.900605671024431 0.999999999905319 GO:0004622 lysophospholipase activity 1/1709 24/18639 0.0416666666666667 0.454432416617905 0.900694190788087 0.999999999905319 GO:0004806 triacylglycerol lipase activity 1/1709 24/18639 0.0416666666666667 0.454432416617905 0.900694190788087 0.999999999905319 GO:0015295 solute:proton symporter activity 1/1709 24/18639 0.0416666666666667 0.454432416617905 0.900694190788087 0.999999999905319 GO:0050431 transforming growth factor beta binding 1/1709 24/18639 0.0416666666666667 0.454432416617905 0.900694190788087 0.999999999905319 GO:0070300 phosphatidic acid binding 1/1709 24/18639 0.0416666666666667 0.454432416617905 0.900694190788087 0.999999999905319 GO:0015932 nucleobase-containing compound transmembrane transporter activity 3/1709 57/18639 0.0526315789473684 0.574019894675249 0.9045359457673 0.999999999905319 GO:0008307 structural constituent of muscle 2/1709 42/18639 0.0476190476190476 0.519351333277606 0.907960873145279 0.999999999905319 GO:0000030 mannosyltransferase activity 1/1709 25/18639 0.04 0.436255119953189 0.909811226938673 0.999999999905319 GO:0015271 outward rectifier potassium channel activity 1/1709 25/18639 0.04 0.436255119953189 0.909811226938673 0.999999999905319 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/1709 25/18639 0.04 0.436255119953189 0.909811226938673 0.999999999905319 GO:0015662 P-type ion transporter activity 1/1709 25/18639 0.04 0.436255119953189 0.909811226938673 0.999999999905319 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/1709 25/18639 0.04 0.436255119953189 0.909811226938673 0.999999999905319 GO:0017056 structural constituent of nuclear pore 1/1709 25/18639 0.04 0.436255119953189 0.909811226938673 0.999999999905319 GO:0140358 P-type transmembrane transporter activity 1/1709 25/18639 0.04 0.436255119953189 0.909811226938673 0.999999999905319 GO:0008408 3'-5' exonuclease activity 3/1709 58/18639 0.0517241379310345 0.564122999939469 0.910738036714111 0.999999999905319 GO:0017116 single-stranded DNA helicase activity 3/1709 58/18639 0.0517241379310345 0.564122999939469 0.910738036714111 0.999999999905319 GO:0016887 ATP hydrolysis activity 31/1709 417/18639 0.0743405275779376 0.810785894397414 0.911030694005733 0.999999999905319 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/1709 43/18639 0.0465116279069767 0.507273395294406 0.91480387730211 0.999999999905319 GO:0003684 damaged DNA binding 4/1709 74/18639 0.0540540540540541 0.589533945882688 0.917090608249504 0.999999999905319 GO:0004529 DNA exonuclease activity 1/1709 26/18639 0.0384615384615385 0.419476076878066 0.918091693961441 0.999999999905319 GO:0008143 poly(A) binding 1/1709 26/18639 0.0384615384615385 0.419476076878066 0.918091693961441 0.999999999905319 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/1709 60/18639 0.05 0.545318899941486 0.922055914743996 0.999999999905319 GO:0005044 scavenger receptor activity 1/1709 27/18639 0.037037037037037 0.403939925882582 0.925612313690657 0.999999999905319 GO:0015252 proton channel activity 1/1709 27/18639 0.037037037037037 0.403939925882582 0.925612313690657 0.999999999905319 GO:0051536 iron-sulfur cluster binding 4/1709 76/18639 0.0526315789473684 0.574019894675249 0.926732858578236 0.999999999905319 GO:0051540 metal cluster binding 4/1709 77/18639 0.051948051948052 0.566565090848297 0.931164598146437 0.999999999905319 GO:0015179 L-amino acid transmembrane transporter activity 3/1709 62/18639 0.0483870967741935 0.527727967685309 0.932045870407427 0.999999999905319 GO:0005242 inward rectifier potassium channel activity 1/1709 28/18639 0.0357142857142857 0.389513499958205 0.932442775537996 0.999999999905319 GO:0051537 2 iron, 2 sulfur cluster binding 1/1709 28/18639 0.0357142857142857 0.389513499958205 0.932442775537996 0.999999999905319 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/1709 46/18639 0.0434782608695652 0.474190347775205 0.932572150964786 0.999999999905319 GO:1901682 sulfur compound transmembrane transporter activity 3/1709 63/18639 0.0476190476190476 0.519351333277606 0.936585773993196 0.999999999905319 GO:0004175 endopeptidase activity 29/1709 405/18639 0.0716049382716049 0.780950523372993 0.937757924740328 0.999999999905319 GO:0005416 amino acid:monoatomic cation symporter activity 1/1709 29/18639 0.0344827586206897 0.376081999959646 0.938646380750266 0.999999999905319 GO:0106222 lncRNA binding 1/1709 29/18639 0.0344827586206897 0.376081999959646 0.938646380750266 0.999999999905319 GO:0099094 ligand-gated monoatomic cation channel activity 8/1709 136/18639 0.0588235294117647 0.641551646989984 0.938798842249021 0.999999999905319 GO:0022804 active transmembrane transporter activity 33/1709 457/18639 0.0722100656455142 0.787550271250287 0.942578190567323 0.999999999905319 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/1709 30/18639 0.0333333333333333 0.363545933294324 0.944280627676531 0.999999999905319 GO:0005267 potassium channel activity 7/1709 124/18639 0.0564516129032258 0.615682628966194 0.944484951568441 0.999999999905319 GO:0008236 serine-type peptidase activity 12/1709 194/18639 0.0618556701030928 0.674621319515241 0.948872180481793 0.999999999905319 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/1709 31/18639 0.032258064516129 0.351818645123539 0.94939774344314 0.999999999905319 GO:0005249 voltage-gated potassium channel activity 5/1709 98/18639 0.0510204081632653 0.556447857083149 0.952719246823103 0.999999999905319 GO:0015106 bicarbonate transmembrane transporter activity 1/1709 32/18639 0.03125 0.340824312463429 0.954045166941402 0.999999999905319 GO:0042910 xenobiotic transmembrane transporter activity 1/1709 32/18639 0.03125 0.340824312463429 0.954045166941402 0.999999999905319 GO:0047498 calcium-dependent phospholipase A2 activity 1/1709 32/18639 0.03125 0.340824312463429 0.954045166941402 0.999999999905319 GO:0071813 lipoprotein particle binding 1/1709 32/18639 0.03125 0.340824312463429 0.954045166941402 0.999999999905319 GO:0071814 protein-lipid complex binding 1/1709 32/18639 0.03125 0.340824312463429 0.954045166941402 0.999999999905319 GO:0005010 insulin-like growth factor receptor activity 2/1709 51/18639 0.0392156862745098 0.427701097993323 0.954629768244244 0.999999999905319 GO:0032934 sterol binding 3/1709 68/18639 0.0441176470588235 0.481163735242488 0.955357747463591 0.999999999905319 GO:0004527 exonuclease activity 4/1709 84/18639 0.0476190476190476 0.519351333277606 0.955968296088924 0.999999999905319 GO:0022843 voltage-gated monoatomic cation channel activity 8/1709 143/18639 0.0559440559440559 0.610147020913551 0.957071766547886 0.999999999905319 GO:0017171 serine hydrolase activity 12/1709 198/18639 0.0606060606060606 0.66099260598968 0.957151232081764 0.999999999905319 GO:0038064 collagen receptor activity 2/1709 53/18639 0.0377358490566038 0.411561433918103 0.96135630464523 0.999999999905319 GO:0008175 tRNA methyltransferase activity 1/1709 34/18639 0.0294117647058824 0.320775823494992 0.962099343878703 0.999999999905319 GO:0016831 carboxy-lyase activity 1/1709 34/18639 0.0294117647058824 0.320775823494992 0.962099343878703 0.999999999905319 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/1709 34/18639 0.0294117647058824 0.320775823494992 0.962099343878703 0.999999999905319 GO:0015171 amino acid transmembrane transporter activity 5/1709 102/18639 0.0490196078431373 0.534626372491653 0.962917724062353 0.999999999905319 GO:0015485 cholesterol binding 2/1709 54/18639 0.037037037037037 0.403939925882582 0.964349753808558 0.999999999905319 GO:0005343 organic acid:sodium symporter activity 1/1709 35/18639 0.0285714285714286 0.311610799966564 0.965580785497155 0.999999999905319 GO:0015108 chloride transmembrane transporter activity 6/1709 121/18639 0.0495867768595041 0.540812132173375 0.970777969061878 0.999999999905319 GO:0003678 DNA helicase activity 3/1709 74/18639 0.0405405405405405 0.442150459412016 0.97101093595066 0.999999999905319 GO:0004497 monooxygenase activity 5/1709 106/18639 0.0471698113207547 0.514451792397629 0.97105702430572 0.999999999905319 GO:0008013 beta-catenin binding 5/1709 106/18639 0.0471698113207547 0.514451792397629 0.97105702430572 0.999999999905319 GO:0016874 ligase activity 9/1709 167/18639 0.0538922155688623 0.587768874188428 0.974210466904099 0.999999999905319 GO:0042162 telomeric DNA binding 1/1709 38/18639 0.0263157894736842 0.287009947337624 0.974221985363687 0.999999999905319 GO:0042887 amide transmembrane transporter activity 1/1709 38/18639 0.0263157894736842 0.287009947337624 0.974221985363687 0.999999999905319 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/1709 60/18639 0.0333333333333333 0.363545933294324 0.978132857501758 0.999999999905319 GO:0019199 transmembrane receptor protein kinase activity 3/1709 78/18639 0.0384615384615385 0.419476076878066 0.978385025702922 0.999999999905319 GO:0008514 organic anion transmembrane transporter activity 16/1709 269/18639 0.0594795539033457 0.648706498071656 0.979727579028145 0.999999999905319 GO:0004812 aminoacyl-tRNA ligase activity 1/1709 41/18639 0.024390243902439 0.266009219483652 0.980694692712688 0.999999999905319 GO:0008227 G protein-coupled amine receptor activity 1/1709 41/18639 0.024390243902439 0.266009219483652 0.980694692712688 0.999999999905319 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1709 41/18639 0.024390243902439 0.266009219483652 0.980694692712688 0.999999999905319 GO:0001653 peptide receptor activity 6/1709 128/18639 0.046875 0.511236468695143 0.980786859868864 0.999999999905319 GO:0030594 neurotransmitter receptor activity 4/1709 97/18639 0.0412371134020619 0.449747546343494 0.981564252725056 0.999999999905319 GO:0015079 potassium ion transmembrane transporter activity 8/1709 160/18639 0.05 0.545318899941486 0.982823463037371 0.999999999905319 GO:0005261 monoatomic cation channel activity 21/1709 341/18639 0.06158357771261 0.67165377705403 0.983588287797173 0.999999999905319 GO:0015293 symporter activity 7/1709 146/18639 0.0479452054794521 0.522908534190466 0.983728865406038 0.999999999905319 GO:0005254 chloride channel activity 3/1709 83/18639 0.036144578313253 0.394206433692641 0.98510929392772 0.999999999905319 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/1709 44/18639 0.0227272727272727 0.24787222724613 0.985542849362748 0.999999999905319 GO:0008509 monoatomic anion transmembrane transporter activity 7/1709 149/18639 0.0469798657718121 0.512380174441665 0.986367539219134 0.999999999905319 GO:0005253 monoatomic anion channel activity 4/1709 103/18639 0.0388349514563107 0.423548660148727 0.987851596346179 0.999999999905319 GO:0140938 histone H3 methyltransferase activity 1/1709 47/18639 0.0212765957446809 0.232050595719781 0.989174015000826 0.999999999905319 GO:0008528 G protein-coupled peptide receptor activity 5/1709 122/18639 0.040983606557377 0.446982704870071 0.989710380023861 0.999999999905319 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 5/1709 122/18639 0.040983606557377 0.446982704870071 0.989710380023861 0.999999999905319 GO:0140767 enzyme-substrate adaptor activity 6/1709 139/18639 0.0431654676258993 0.470778906424305 0.99030064845095 0.999999999905319 GO:0015291 secondary active transmembrane transporter activity 16/1709 287/18639 0.0557491289198606 0.60802107310549 0.990999726352721 0.999999999905319 GO:0005004 GPI-linked ephrin receptor activity 1/1709 49/18639 0.0204081632653061 0.22257914283326 0.991072865546887 0.999999999905319 GO:0005008 hepatocyte growth factor receptor activity 1/1709 49/18639 0.0204081632653061 0.22257914283326 0.991072865546887 0.999999999905319 GO:0005009 insulin receptor activity 1/1709 49/18639 0.0204081632653061 0.22257914283326 0.991072865546887 0.999999999905319 GO:0005011 macrophage colony-stimulating factor receptor activity 1/1709 49/18639 0.0204081632653061 0.22257914283326 0.991072865546887 0.999999999905319 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/1709 49/18639 0.0204081632653061 0.22257914283326 0.991072865546887 0.999999999905319 GO:0005020 stem cell factor receptor activity 1/1709 49/18639 0.0204081632653061 0.22257914283326 0.991072865546887 0.999999999905319 GO:0008288 boss receptor activity 1/1709 49/18639 0.0204081632653061 0.22257914283326 0.991072865546887 0.999999999905319 GO:0036332 placental growth factor receptor activity 1/1709 49/18639 0.0204081632653061 0.22257914283326 0.991072865546887 0.999999999905319 GO:0038062 protein tyrosine kinase collagen receptor activity 1/1709 49/18639 0.0204081632653061 0.22257914283326 0.991072865546887 0.999999999905319 GO:0060175 brain-derived neurotrophic factor receptor activity 1/1709 49/18639 0.0204081632653061 0.22257914283326 0.991072865546887 0.999999999905319 GO:0005496 steroid binding 4/1709 108/18639 0.037037037037037 0.403939925882582 0.991473262094596 0.999999999905319 GO:0005244 voltage-gated monoatomic ion channel activity 8/1709 173/18639 0.046242774566474 0.504341179136635 0.991857269454722 0.999999999905319 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/1709 91/18639 0.032967032967033 0.359550923038343 0.991893190575415 0.999999999905319 GO:0005006 epidermal growth factor receptor activity 1/1709 50/18639 0.02 0.218127559976595 0.99189354724567 0.999999999905319 GO:0005007 fibroblast growth factor receptor activity 1/1709 50/18639 0.02 0.218127559976595 0.99189354724567 0.999999999905319 GO:0005017 platelet-derived growth factor receptor activity 1/1709 50/18639 0.02 0.218127559976595 0.99189354724567 0.999999999905319 GO:0005019 platelet-derived growth factor beta-receptor activity 1/1709 50/18639 0.02 0.218127559976595 0.99189354724567 0.999999999905319 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/1709 73/18639 0.0273972602739726 0.298804876680266 0.992600324748309 0.999999999905319 GO:0005021 vascular endothelial growth factor receptor activity 1/1709 51/18639 0.0196078431372549 0.213850548996661 0.992638822825698 0.999999999905319 GO:0005030 neurotrophin receptor activity 1/1709 51/18639 0.0196078431372549 0.213850548996661 0.992638822825698 0.999999999905319 GO:0005272 sodium channel activity 1/1709 51/18639 0.0196078431372549 0.213850548996661 0.992638822825698 0.999999999905319 GO:0022832 voltage-gated channel activity 8/1709 175/18639 0.0457142857142857 0.498577279946502 0.992763603568125 0.999999999905319 GO:0004252 serine-type endopeptidase activity 8/1709 176/18639 0.0454545454545455 0.49574445449226 0.993180257919051 0.999999999905319 GO:0005003 ephrin receptor activity 1/1709 53/18639 0.0188679245283019 0.205780716959051 0.993930219252731 0.999999999905319 GO:0005005 transmembrane-ephrin receptor activity 1/1709 53/18639 0.0188679245283019 0.205780716959051 0.993930219252731 0.999999999905319 GO:0015103 inorganic anion transmembrane transporter activity 7/1709 165/18639 0.0424242424242424 0.462694824192776 0.994867797776702 0.999999999905319 GO:0046873 metal ion transmembrane transporter activity 27/1709 450/18639 0.06 0.654382679929783 0.994910769562227 0.999999999905319 GO:0008170 N-methyltransferase activity 3/1709 98/18639 0.0306122448979592 0.33386871424989 0.995287530427317 0.999999999905319 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/1709 56/18639 0.0178571428571429 0.194756749979102 0.995455418906985 0.999999999905319 GO:0015370 solute:sodium symporter activity 2/1709 79/18639 0.0253164556962025 0.276110835413411 0.995553215926005 0.999999999905319 GO:0005201 extracellular matrix structural constituent 7/1709 168/18639 0.0416666666666667 0.454432416617905 0.995751351413215 0.999999999905319 GO:0015276 ligand-gated monoatomic ion channel activity 8/1709 186/18639 0.043010752688172 0.469091526831386 0.996270681165208 0.999999999905319 GO:0022834 ligand-gated channel activity 8/1709 188/18639 0.0425531914893617 0.464101191439563 0.99670208662205 0.999999999905319 GO:0046943 carboxylic acid transmembrane transporter activity 8/1709 188/18639 0.0425531914893617 0.464101191439563 0.99670208662205 0.999999999905319 GO:0005216 monoatomic ion channel activity 26/1709 448/18639 0.0580357142857143 0.632959437432082 0.996840853906092 0.999999999905319 GO:0005342 organic acid transmembrane transporter activity 8/1709 189/18639 0.0423280423280423 0.461645629580094 0.996899522854666 0.999999999905319 GO:0015081 sodium ion transmembrane transporter activity 6/1709 164/18639 0.0365853658536585 0.399013829225478 0.998132732598169 0.999999999905319 GO:0008173 RNA methyltransferase activity 1/1709 67/18639 0.0149253731343284 0.162781761176563 0.998427871578329 0.999999999905319 GO:0016500 protein-hormone receptor activity 1/1709 67/18639 0.0149253731343284 0.162781761176563 0.998427871578329 0.999999999905319 GO:0042054 histone methyltransferase activity 1/1709 67/18639 0.0149253731343284 0.162781761176563 0.998427871578329 0.999999999905319 GO:0003777 microtubule motor activity 1/1709 68/18639 0.0147058823529412 0.160387911747496 0.998572539221697 0.999999999905319 GO:0016279 protein-lysine N-methyltransferase activity 1/1709 69/18639 0.0144927536231884 0.158063449258402 0.998703901586143 0.999999999905319 GO:0098960 postsynaptic neurotransmitter receptor activity 1/1709 69/18639 0.0144927536231884 0.158063449258402 0.998703901586143 0.999999999905319 GO:0016278 lysine N-methyltransferase activity 1/1709 70/18639 0.0142857142857143 0.155805399983282 0.998823181725576 0.999999999905319 GO:0015294 solute:monoatomic cation symporter activity 3/1709 116/18639 0.0258620689655172 0.282061499969734 0.998874471143917 0.999999999905319 GO:0008276 protein methyltransferase activity 2/1709 95/18639 0.0210526315789474 0.229607957870099 0.998881074536003 0.999999999905319 GO:0140101 catalytic activity, acting on a tRNA 4/1709 139/18639 0.0287769784172662 0.31385260428287 0.999145404208176 0.999999999905319 GO:0003730 mRNA 3'-UTR binding 11/1709 262/18639 0.0419847328244275 0.45790136636308 0.999342732065376 0.999999999905319 GO:0008194 UDP-glycosyltransferase activity 4/1709 145/18639 0.0275862068965517 0.300865599967717 0.999461843591886 0.999999999905319 GO:0016758 hexosyltransferase activity 6/1709 197/18639 0.0304568527918782 0.332173949202936 0.999818459610973 0.999999999905319 GO:0022836 gated channel activity 13/1709 318/18639 0.0408805031446541 0.445858220077945 0.999847863971603 0.999999999905319 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 4/1709 167/18639 0.0239520958083832 0.261230610750413 0.999904882505102 0.999999999905319 GO:0008168 methyltransferase activity 4/1709 204/18639 0.0196078431372549 0.213850548996661 0.999995357568916 0.999999999905319 GO:0016741 transferase activity, transferring one-carbon groups 4/1709 215/18639 0.0186046511627907 0.202909358117762 0.999998146338318 0.999999999905319 GO:0045182 translation regulator activity 10/1709 356/18639 0.0280898876404494 0.306358932551397 0.999999628155122 0.999999999905319 GO:0030371 translation repressor activity 4/1709 329/18639 0.0121580547112462 0.132600340411304 0.999999999905319 0.999999999905319