ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0031720 haptoglobin binding 7/46 10/18639 0.7 283.636956521739 4.12390326420061e-17 5.48479134138681e-15 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 10/46 68/18639 0.147058823529412 59.5875959079284 7.6921188800545e-16 5.11525905523625e-14 GO:0005344 oxygen carrier activity 7/46 14/18639 0.5 202.597826086957 1.17081865055641e-15 5.1906293508001e-14 GO:0009055 electron transfer activity 10/46 116/18639 0.0862068965517241 34.9306596701649 1.98293772764634e-13 6.27940043091832e-12 GO:0022853 active monoatomic ion transmembrane transporter activity 10/46 118/18639 0.0847457627118644 34.3386145910096 2.36067685372869e-13 6.27940043091832e-12 GO:0015078 proton transmembrane transporter activity 11/46 185/18639 0.0594594594594595 24.092714453584 6.73580609598946e-13 1.493103684611e-11 GO:0019825 oxygen binding 7/46 34/18639 0.205882352941176 83.4226342710997 1.76915445662686e-12 3.36139346759103e-11 GO:0015399 primary active transmembrane transporter activity 10/46 166/18639 0.0602409638554217 24.4093766369827 7.39073039699834e-12 1.22870892850097e-10 GO:0004601 peroxidase activity 7/46 57/18639 0.12280701754386 49.7608695652174 8.33543769846003e-11 1.23179245988354e-09 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 7/46 59/18639 0.11864406779661 48.0740604274134 1.07162077022359e-10 1.42525562439737e-09 GO:0008137 NADH dehydrogenase (ubiquinone) activity 6/46 41/18639 0.146341463414634 59.2969247083775 6.78583320707125e-10 8.20468924127706e-09 GO:0003954 NADH dehydrogenase activity 6/46 44/18639 0.136363636363636 55.25395256917 1.05946225148989e-09 1.17423732873462e-08 GO:0016209 antioxidant activity 7/46 86/18639 0.0813953488372093 32.9810414560162 1.60623110276281e-09 1.64329797436503e-08 GO:0020037 heme binding 8/46 142/18639 0.0563380281690141 22.8279240661359 1.90170045088389e-09 1.80661542833969e-08 GO:0046906 tetrapyrrole binding 8/46 152/18639 0.0526315789473684 21.3260869565217 3.26219000452147e-09 2.89247513734237e-08 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 6/46 58/18639 0.103448275862069 41.9167916041979 5.92008155891929e-09 4.92106779585166e-08 GO:0016651 oxidoreductase activity, acting on NAD(P)H 6/46 88/18639 0.0681818181818182 27.626976284585 7.50019719711831e-08 5.86780133656903e-07 GO:0022804 active transmembrane transporter activity 10/46 457/18639 0.0218818380743982 8.86642564931976 1.3159847921988e-07 9.72366540902445e-07 GO:0140104 molecular carrier activity 7/46 249/18639 0.0281124497991968 11.3910424305919 2.39581735628281e-06 1.67707214939796e-05 GO:0004129 cytochrome-c oxidase activity 3/46 15/18639 0.2 81.0391304347826 6.26922179692755e-06 4.16903249495682e-05 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/46 16/18639 0.1875 75.9741847826087 7.70262434481916e-06 4.8783287517188e-05 GO:0005506 iron ion binding 4/46 154/18639 0.025974025974026 10.5245623941276 0.000558321155034106 0.00337530516452437 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/46 27/18639 0.0740740740740741 30.0144927536232 0.0020108779907493 0.0116281205552025 GO:0051537 2 iron, 2 sulfur cluster binding 2/46 28/18639 0.0714285714285714 28.9425465838509 0.00216216593490217 0.0119820028892495 GO:0005507 copper ion binding 2/46 63/18639 0.0317460317460317 12.8633540372671 0.0105759697830289 0.0562641592457138 GO:0051536 iron-sulfur cluster binding 2/46 76/18639 0.0263157894736842 10.6630434782609 0.0151239454901531 0.0763671315257624 GO:0051540 metal cluster binding 2/46 77/18639 0.025974025974026 10.5245623941276 0.0155031018886886 0.0763671315257624 GO:0016868 intramolecular phosphotransferase activity 1/46 10/18639 0.1 40.5195652173913 0.0244129773341912 0.115961642337408 GO:0000149 SNARE binding 2/46 106/18639 0.0188679245283019 7.64520098441345 0.0281874366382362 0.129273416306394 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/46 13/18639 0.0769230769230769 31.1688963210702 0.0316224912437644 0.131430979231896 GO:0035673 oligopeptide transmembrane transporter activity 1/46 13/18639 0.0769230769230769 31.1688963210702 0.0316224912437644 0.131430979231896 GO:0045159 myosin II binding 1/46 13/18639 0.0769230769230769 31.1688963210702 0.0316224912437644 0.131430979231896 GO:0032036 myosin heavy chain binding 1/46 14/18639 0.0714285714285714 28.9425465838509 0.0340140603086626 0.137086970334913 GO:0031386 protein tag activity 1/46 15/18639 0.0666666666666667 27.0130434782609 0.0363998510858864 0.138319434126368 GO:0141047 molecular tag activity 1/46 15/18639 0.0666666666666667 27.0130434782609 0.0363998510858864 0.138319434126368 GO:0005521 lamin binding 1/46 16/18639 0.0625 25.3247282608696 0.0387798772268901 0.141183360401274 GO:0008429 phosphatidylethanolamine binding 1/46 17/18639 0.0588235294117647 23.8350383631714 0.0411541523516048 0.141183360401274 GO:0048038 quinone binding 1/46 17/18639 0.0588235294117647 23.8350383631714 0.0411541523516048 0.141183360401274 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/46 18/18639 0.0555555555555556 22.5108695652174 0.0435226900485131 0.141183360401274 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/46 18/18639 0.0555555555555556 22.5108695652174 0.0435226900485131 0.141183360401274 GO:0050811 GABA receptor binding 1/46 18/18639 0.0555555555555556 22.5108695652174 0.0435226900485131 0.141183360401274 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/46 21/18639 0.0476190476190476 19.2950310559006 0.0505940139869644 0.160214377625387 GO:0140517 protein-RNA adaptor activity 1/46 22/18639 0.0454545454545455 18.4179841897233 0.052939737230954 0.163743838412021 GO:0070840 dynein complex binding 1/46 24/18639 0.0416666666666667 16.883152173913 0.0576141872562093 0.17415197511536 GO:0008198 ferrous iron binding 1/46 26/18639 0.0384615384615385 15.5844481605351 0.0622660645182406 0.18157343379672 GO:0015252 proton channel activity 1/46 27/18639 0.037037037037037 15.0072463768116 0.0645835716923748 0.18157343379672 GO:0035255 ionotropic glutamate receptor binding 1/46 27/18639 0.037037037037037 15.0072463768116 0.0645835716923748 0.18157343379672 GO:0016866 intramolecular transferase activity 1/46 28/18639 0.0357142857142857 14.4712732919255 0.0668954756093179 0.18157343379672 GO:0097718 disordered domain specific binding 1/46 28/18639 0.0357142857142857 14.4712732919255 0.0668954756093179 0.18157343379672 GO:0003785 actin monomer binding 1/46 29/18639 0.0344827586206897 13.972263868066 0.0692017895162532 0.184076760113234 GO:0016769 transferase activity, transferring nitrogenous groups 1/46 30/18639 0.0333333333333333 13.5065217391304 0.0715025266297542 0.1851904550579 GO:0016853 isomerase activity 2/46 180/18639 0.0111111111111111 4.50217391304348 0.0728162781838446 0.1851904550579 GO:0072349 modified amino acid transmembrane transporter activity 1/46 31/18639 0.032258064516129 13.0708274894811 0.073797700135855 0.1851904550579 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/46 33/18639 0.0303030303030303 12.2786561264822 0.0783714089177087 0.192039766113241 GO:0004857 enzyme inhibitor activity 3/46 416/18639 0.00721153846153846 2.92208403010033 0.0829469241231943 0.192039766113241 GO:0045505 dynein intermediate chain binding 1/46 36/18639 0.0277777777777778 11.2554347826087 0.0851905729374529 0.192039766113241 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/46 36/18639 0.0277777777777778 11.2554347826087 0.0851905729374529 0.192039766113241 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/46 36/18639 0.0277777777777778 11.2554347826087 0.0851905729374529 0.192039766113241 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/46 36/18639 0.0277777777777778 11.2554347826087 0.0851905729374529 0.192039766113241 GO:0030280 structural constituent of skin epidermis 1/46 37/18639 0.027027027027027 10.9512338425382 0.0874526400043171 0.193008722701463 GO:0042887 amide transmembrane transporter activity 1/46 38/18639 0.0263157894736842 10.6630434782609 0.0897092349166817 0.193008722701463 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/46 39/18639 0.0256410256410256 10.3896321070234 0.0919603706187316 0.193008722701463 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/46 40/18639 0.025 10.1298913043478 0.094206060024728 0.193008722701463 GO:0008307 structural constituent of muscle 1/46 42/18639 0.0238095238095238 9.64751552795031 0.0986811514563871 0.193008722701463 GO:0016859 cis-trans isomerase activity 1/46 42/18639 0.0238095238095238 9.64751552795031 0.0986811514563871 0.193008722701463 GO:0019894 kinesin binding 1/46 42/18639 0.0238095238095238 9.64751552795031 0.0986811514563871 0.193008722701463 GO:0035198 miRNA binding 1/46 42/18639 0.0238095238095238 9.64751552795031 0.0986811514563871 0.193008722701463 GO:0048487 beta-tubulin binding 1/46 42/18639 0.0238095238095238 9.64751552795031 0.0986811514563871 0.193008722701463 GO:0048156 tau protein binding 1/46 43/18639 0.0232558139534884 9.42315470171891 0.100910579161555 0.194508797514301 GO:0043014 alpha-tubulin binding 1/46 44/18639 0.0227272727272727 9.20899209486166 0.103134611929815 0.195955762666649 GO:0035254 glutamate receptor binding 1/46 49/18639 0.0204081632653061 8.26929902395741 0.114174297483329 0.213875796694123 GO:0003743 translation initiation factor activity 1/46 51/18639 0.0196078431372549 7.94501278772378 0.118552851677336 0.215993551686105 GO:0030544 Hsp70 protein binding 1/46 51/18639 0.0196078431372549 7.94501278772378 0.118552851677336 0.215993551686105 GO:0017069 snRNA binding 1/46 54/18639 0.0185185185185185 7.5036231884058 0.125081011964591 0.22480776474717 GO:0030170 pyridoxal phosphate binding 1/46 56/18639 0.0178571428571429 7.23563664596273 0.12940681734805 0.229481422763875 GO:0070279 vitamin B6 binding 1/46 57/18639 0.0175438596491228 7.10869565217391 0.131561866931109 0.230233267129442 GO:0061980 regulatory RNA binding 1/46 58/18639 0.0172413793103448 6.98613193403298 0.133711697634003 0.23095656864055 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/46 60/18639 0.0166666666666667 6.75326086956522 0.137995751804141 0.235300448589112 GO:1901682 sulfur compound transmembrane transporter activity 1/46 63/18639 0.0158730158730159 6.43167701863354 0.144382999488978 0.243075176354862 GO:0019843 rRNA binding 1/46 65/18639 0.0153846153846154 6.23377926421405 0.14861541841643 0.247073133117316 GO:0001664 G protein-coupled receptor binding 2/46 297/18639 0.00673400673400673 2.72859025032938 0.166453416311697 0.271589440163632 GO:0044183 protein folding chaperone 1/46 75/18639 0.0133333333333333 5.40260869565217 0.169472196060653 0.271589440163632 GO:0031625 ubiquitin protein ligase binding 2/46 302/18639 0.00662251655629139 2.68341491505903 0.170832776959051 0.271589440163632 GO:0017022 myosin binding 1/46 76/18639 0.0131578947368421 5.33152173913043 0.171530172734926 0.271589440163632 GO:0000049 tRNA binding 1/46 80/18639 0.0125 5.06494565217391 0.179712308553882 0.278620005996206 GO:0008135 translation factor activity, RNA binding 1/46 83/18639 0.0120481927710843 4.88187532739654 0.185796980589188 0.278620005996206 GO:0004860 protein kinase inhibitor activity 1/46 84/18639 0.0119047619047619 4.82375776397515 0.187815375657786 0.278620005996206 GO:0051117 ATPase binding 1/46 84/18639 0.0119047619047619 4.82375776397515 0.187815375657786 0.278620005996206 GO:0180051 translation factor activity 1/46 84/18639 0.0119047619047619 4.82375776397515 0.187815375657786 0.278620005996206 GO:0044389 ubiquitin-like protein ligase binding 2/46 322/18639 0.0062111801242236 2.51674318120443 0.188539853681643 0.278620005996206 GO:0019210 kinase inhibitor activity 1/46 90/18639 0.0111111111111111 4.50217391304348 0.199823355231594 0.292049519184638 GO:0051219 phosphoprotein binding 1/46 93/18639 0.010752688172043 4.35694249649369 0.205762041096117 0.296699213159045 GO:0016410 N-acyltransferase activity 1/46 94/18639 0.0106382978723404 4.31059204440333 0.207732004759957 0.296699213159045 GO:0004867 serine-type endopeptidase inhibitor activity 1/46 95/18639 0.0105263157894737 4.26521739130435 0.209697188247746 0.296699213159045 GO:0005200 structural constituent of cytoskeleton 1/46 112/18639 0.00892857142857143 3.61781832298137 0.242384829835359 0.339338761769502 GO:0015631 tubulin binding 2/46 385/18639 0.00519480519480519 2.10491247882552 0.24567446116557 0.340361493073134 GO:0003697 single-stranded DNA binding 1/46 121/18639 0.00826446280991736 3.34872439813151 0.259150741109543 0.350624356285689 GO:0051082 unfolded protein binding 1/46 121/18639 0.00826446280991736 3.34872439813151 0.259150741109543 0.350624356285689 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/46 122/18639 0.00819672131147541 3.32127583749109 0.260991062197618 0.350624356285689 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/46 128/18639 0.0078125 3.1655910326087 0.271939440547815 0.361679455928594 GO:0031072 heat shock protein binding 1/46 131/18639 0.00763358778625954 3.09309658148025 0.277353966536161 0.363989757325581 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/46 132/18639 0.00757575757575758 3.06966403162055 0.279150039452701 0.363989757325581 GO:0051087 protein-folding chaperone binding 1/46 134/18639 0.00746268656716418 3.02384815055159 0.282729094148499 0.365077373997576 GO:0003779 actin binding 2/46 443/18639 0.00451467268623025 1.82932574344882 0.298945470690206 0.382305265401898 GO:0019842 vitamin binding 1/46 150/18639 0.00666666666666667 2.70130434782609 0.310742533921272 0.393607209633612 GO:0004866 endopeptidase inhibitor activity 1/46 161/18639 0.0062111801242236 2.51674318120443 0.329377936736693 0.413276090433775 GO:0016874 ligase activity 1/46 167/18639 0.00598802395209581 2.42632127050247 0.339334008984022 0.41805982131365 GO:0005201 extracellular matrix structural constituent 1/46 168/18639 0.00595238095238095 2.41187888198758 0.340979236116262 0.41805982131365 GO:0030414 peptidase inhibitor activity 1/46 169/18639 0.00591715976331361 2.39760740931309 0.342620455061563 0.41805982131365 GO:0005543 phospholipid binding 2/46 497/18639 0.00402414486921529 1.630566004724 0.34813372867441 0.418456154337688 GO:0003823 antigen binding 1/46 174/18639 0.00574712643678161 2.32871064467766 0.350766760403378 0.418456154337688 GO:0003735 structural constituent of ribosome 1/46 175/18639 0.00571428571428571 2.31540372670807 0.352384129968579 0.418456154337688 GO:0061135 endopeptidase regulator activity 1/46 184/18639 0.00543478260869565 2.20215028355388 0.366764197169127 0.431678214367202 GO:0005516 calmodulin binding 1/46 207/18639 0.00483091787439614 1.95746691871456 0.402109048487256 0.468495009791262 GO:0051015 actin filament binding 1/46 209/18639 0.00478468899521531 1.93873517786561 0.405089670120264 0.468495009791262 GO:0061134 peptidase regulator activity 1/46 226/18639 0.00442477876106195 1.79290111581377 0.42984494335142 0.490884531177676 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/46 229/18639 0.00436681222707424 1.76941332827036 0.434107651714682 0.490884531177676 GO:0000287 magnesium ion binding 1/46 230/18639 0.00434782608695652 1.7617202268431 0.435521614127562 0.490884531177676 GO:0042393 histone binding 1/46 247/18639 0.00404858299595142 1.64046822742475 0.459036833408915 0.51304116675114 GO:0019887 protein kinase regulator activity 1/46 255/18639 0.00392156862745098 1.58900255754476 0.469768548925195 0.520660141725424 GO:0008514 organic anion transmembrane transporter activity 1/46 269/18639 0.00371747211895911 1.50630353967997 0.488050069717755 0.536451729524475 GO:0016791 phosphatase activity 1/46 273/18639 0.00366300366300366 1.4842331581462 0.493159116546973 0.5373612366479 GO:0008017 microtubule binding 1/46 276/18639 0.0036231884057971 1.46810018903592 0.496958136148058 0.5373612366479 GO:0030246 carbohydrate binding 1/46 280/18639 0.00357142857142857 1.44712732919255 0.501980190837328 0.538414236946488 GO:0019207 kinase regulator activity 1/46 287/18639 0.00348432055749129 1.41183154067566 0.510651023393908 0.543332688891118 GO:0051020 GTPase binding 1/46 315/18639 0.00317460317460317 1.28633540372671 0.543881389067119 0.57409702179307 GO:0045296 cadherin binding 1/46 334/18639 0.0029940119760479 1.21316063525124 0.565162495924102 0.591863086282721 GO:0005261 monoatomic cation channel activity 1/46 341/18639 0.00293255131964809 1.18825704449828 0.572755454823713 0.595128714777765 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 1/46 349/18639 0.00286532951289398 1.16101906067024 0.581274368732266 0.599298380165825 GO:0042578 phosphoric ester hydrolase activity 1/46 363/18639 0.00275482093663912 1.11624146604384 0.595784364550914 0.609533234502088 GO:0046982 protein heterodimerization activity 1/46 369/18639 0.002710027100271 1.09809119830329 0.601851279456791 0.611039848608803 GO:0005216 monoatomic ion channel activity 1/46 448/18639 0.00223214285714286 0.904454580745342 0.673887444207888 0.678992652118553 GO:0140297 DNA-binding transcription factor binding 1/46 488/18639 0.00204918032786885 0.830318959372773 0.705329819053332 0.705329819053332