ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0048608 reproductive structure development 11/83 424/18722 2.63530002810622e-06 0.00272566113437828 KRT19/IGF2/HTRA1/KRT8/TNFSF10/SPINT1/ASCL2/SERPINF1/SERPINE2/FSTL3/ADGRG1 11 GO:0061458 reproductive system development 11/83 427/18722 2.82013567964643e-06 0.00272566113437828 KRT19/IGF2/HTRA1/KRT8/TNFSF10/SPINT1/ASCL2/SERPINF1/SERPINE2/FSTL3/ADGRG1 11 GO:0001892 embryonic placenta development 5/83 82/18722 3.16525146119945e-05 0.0203947702483285 KRT19/IGF2/KRT8/SPINT1/ASCL2 5 GO:0001890 placenta development 6/83 144/18722 4.32667637530669e-05 0.0209086635836696 KRT19/IGF2/HTRA1/KRT8/SPINT1/ASCL2 6 GO:0016052 carbohydrate catabolic process 6/83 154/18722 6.29278657158077e-05 0.0243279128857313 LDHA/ALDOA/AGL/GAPDH/APP/LRP5 6 GO:0001503 ossification 9/83 408/18722 8.03307072780106e-05 0.0258798761947324 FBN2/IGF2/SLC26A2/ISG15/ATP2B1/LRP5/PBX1/FSTL3/DHX36 9 GO:0048732 gland development 9/83 436/18722 0.00013284178727267 0.0366833106854388 IGF2/WLS/PRKDC/SERPINF1/SERPINE2/LRP5/PBX1/FSTL3/MET 9 GO:0007179 transforming growth factor beta receptor signaling pathway 6/83 198/18722 0.000248990181390193 0.0601622525784055 FBN2/PEG10/HTRA1/JUN/PARP1/ENG 6 GO:0006096 glycolytic process 4/83 81/18722 0.000460905577447341 0.0633293845902408 LDHA/ALDOA/GAPDH/APP 4 GO:0006757 ATP generation from ADP 4/83 82/18722 0.000482918555028641 0.0633293845902408 LDHA/ALDOA/GAPDH/APP 4 GO:0043434 response to peptide hormone 8/83 414/18722 0.000495658851647337 0.0633293845902408 IGF2/PRKDC/TNFSF10/CYP11A1/BTG1/ATP2B1/LRP5/PARP1 8 GO:0048568 embryonic organ development 8/83 427/18722 0.000607288087596014 0.0633293845902408 FBN2/KRT19/IGF2/KRT8/SPINT1/ASCL2/PBX1/ENG 8 GO:0052548 regulation of endopeptidase activity 8/83 432/18722 0.000655300084011315 0.0633293845902408 APLP2/TNFSF10/SPINT1/GAPDH/APP/SERPINF1/EGLN3/SERPINE2 8 GO:0046031 ADP metabolic process 4/83 90/18722 0.000686814573773368 0.0633293845902408 LDHA/ALDOA/GAPDH/APP 4 GO:0030501 positive regulation of bone mineralization 3/83 40/18722 0.000737429033656548 0.0633293845902408 FBN2/ISG15/ATP2B1 3 GO:0071526 semaphorin-plexin signaling pathway 3/83 40/18722 0.000737429033656548 0.0633293845902408 NRP2/MET/SEMA6A 3 GO:0006979 response to oxidative stress 8/83 446/18722 0.000806283325439995 0.0633293845902408 LDHA/PDLIM1/JUN/BTG1/APP/PAGE4/PARP1/MET 8 GO:0071560 cellular response to transforming growth factor beta stimulus 6/83 250/18722 0.000854292994925625 0.0633293845902408 FBN2/PEG10/HTRA1/JUN/PARP1/ENG 6 GO:0031960 response to corticosteroid 5/83 167/18722 0.000881307137200065 0.0633293845902408 AGL/SERPINF1/ATP2B1/PARP1/ENG 5 GO:0010951 negative regulation of endopeptidase activity 6/83 252/18722 0.000890303200558032 0.0633293845902408 APLP2/SPINT1/GAPDH/APP/SERPINF1/SERPINE2 6 GO:0071559 response to transforming growth factor beta 6/83 256/18722 0.00096583108325242 0.0633293845902408 FBN2/PEG10/HTRA1/JUN/PARP1/ENG 6 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 6/83 256/18722 0.00096583108325242 0.0633293845902408 FBN2/PEG10/HTRA1/PARP1/FSTL3/ENG 6 GO:0006165 nucleoside diphosphate phosphorylation 4/83 99/18722 0.000981775024411855 0.0633293845902408 LDHA/ALDOA/GAPDH/APP 4 GO:0052547 regulation of peptidase activity 8/83 461/18722 0.000997966598203035 0.0633293845902408 APLP2/TNFSF10/SPINT1/GAPDH/APP/SERPINF1/EGLN3/SERPINE2 8 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 7/83 355/18722 0.00100325703919785 0.0633293845902408 FBN2/PEG10/HTRA1/JUN/PARP1/FSTL3/ENG 7 GO:0033690 positive regulation of osteoblast proliferation 2/83 11/18722 0.00104063080874368 0.0633293845902408 ITGAV/LRP5 2 GO:0046939 nucleotide phosphorylation 4/83 101/18722 0.00105774659385032 0.0633293845902408 LDHA/ALDOA/GAPDH/APP 4 GO:0010466 negative regulation of peptidase activity 6/83 262/18722 0.00108827234444377 0.0633293845902408 APLP2/SPINT1/GAPDH/APP/SERPINF1/SERPINE2 6 GO:0050919 negative chemotaxis 3/83 46/18722 0.00111154603358437 0.0633293845902408 NRP2/ITGAV/SEMA6A 3 GO:0009135 purine nucleoside diphosphate metabolic process 4/83 103/18722 0.00113775736658124 0.0633293845902408 LDHA/ALDOA/GAPDH/APP 4 GO:0009179 purine ribonucleoside diphosphate metabolic process 4/83 103/18722 0.00113775736658124 0.0633293845902408 LDHA/ALDOA/GAPDH/APP 4 GO:0009150 purine ribonucleotide metabolic process 7/83 368/18722 0.00123508730715186 0.0633293845902408 LDHA/ALDOA/SLC26A2/GAPDH/APP/PARP1/ACSS1 7 GO:0070493 thrombin-activated receptor signaling pathway 2/83 12/18722 0.00124516524903468 0.0633293845902408 IQGAP2/MET 2 GO:0006090 pyruvate metabolic process 4/83 106/18722 0.00126559767741057 0.0633293845902408 LDHA/ALDOA/GAPDH/APP 4 GO:0009185 ribonucleoside diphosphate metabolic process 4/83 106/18722 0.00126559767741057 0.0633293845902408 LDHA/ALDOA/GAPDH/APP 4 GO:0061138 morphogenesis of a branching epithelium 5/83 182/18722 0.00129317357863572 0.0633293845902408 SPINT1/LRP5/PBX1/MET/ENG 5 GO:0001654 eye development 7/83 371/18722 0.00129412370687519 0.0633293845902408 FBN2/FLT1/TENM3/SERPINF1/ATP2B1/LRP5/PBX1 7 GO:0038084 vascular endothelial growth factor signaling pathway 3/83 49/18722 0.00133625453465513 0.0633293845902408 FLT1/NRP2/SEMA6A 3 GO:0045778 positive regulation of ossification 3/83 49/18722 0.00133625453465513 0.0633293845902408 FBN2/ISG15/ATP2B1 3 GO:0070169 positive regulation of biomineral tissue development 3/83 49/18722 0.00133625453465513 0.0633293845902408 FBN2/ISG15/ATP2B1 3 GO:0150063 visual system development 7/83 375/18722 0.00137625898452491 0.0633293845902408 FBN2/FLT1/TENM3/SERPINF1/ATP2B1/LRP5/PBX1 7 GO:0110151 positive regulation of biomineralization 3/83 50/18722 0.00141702780046722 0.0633293845902408 FBN2/ISG15/ATP2B1 3 GO:1900115 extracellular regulation of signal transduction 2/83 13/18722 0.00146732775356883 0.0633293845902408 FBN2/LRPAP1 2 GO:1900116 extracellular negative regulation of signal transduction 2/83 13/18722 0.00146732775356883 0.0633293845902408 FBN2/LRPAP1 2 GO:0030099 myeloid cell differentiation 7/83 381/18722 0.00150706243722249 0.0633293845902408 CSF3R/JUN/PRKDC/APP/ISG15/PARP1/FSTL3 7 GO:0048880 sensory system development 7/83 381/18722 0.00150706243722249 0.0633293845902408 FBN2/FLT1/TENM3/SERPINF1/ATP2B1/LRP5/PBX1 7 GO:0009259 ribonucleotide metabolic process 7/83 385/18722 0.00159953009904549 0.0648081187303908 LDHA/ALDOA/SLC26A2/GAPDH/APP/PARP1/ACSS1 7 GO:0006753 nucleoside phosphate metabolic process 8/83 497/18722 0.00160930662134442 0.0648081187303908 LDHA/ALDOA/SMPDL3A/SLC26A2/GAPDH/APP/PARP1/ACSS1 8 GO:0002244 hematopoietic progenitor cell differentiation 4/83 114/18722 0.00165513037035727 0.065293204202053 FLT1/PRKDC/FSTL3/DHX36 4 GO:0030278 regulation of ossification 4/83 115/18722 0.00170905111244251 0.0659606807477112 FBN2/ISG15/ATP2B1/PBX1 4 GO:0001763 morphogenesis of a branching structure 5/83 196/18722 0.00179226829552956 0.0659606807477112 SPINT1/LRP5/PBX1/MET/ENG 5 GO:0031032 actomyosin structure organization 5/83 196/18722 0.00179226829552956 0.0659606807477112 KRT19/PDLIM1/KRT8/MYH10/MET 5 GO:0071248 cellular response to metal ion 5/83 197/18722 0.00183263220893926 0.0659606807477112 JUN/APP/SERPINF1/PARP1/FSTL3 5 GO:0006163 purine nucleotide metabolic process 7/83 396/18722 0.001876791226655 0.0659606807477112 LDHA/ALDOA/SLC26A2/GAPDH/APP/PARP1/ACSS1 7 GO:0019693 ribose phosphate metabolic process 7/83 396/18722 0.001876791226655 0.0659606807477112 LDHA/ALDOA/SLC26A2/GAPDH/APP/PARP1/ACSS1 7 GO:0032481 positive regulation of type I interferon production 3/83 58/18722 0.00217473974692053 0.0732429856710301 GAPDH/ISG15/DHX36 3 GO:0030198 extracellular matrix organization 6/83 301/18722 0.00219966909720963 0.0732429856710301 ADAMTSL4/SPINT1/APP/TGFBI/ENG/COL14A1 6 GO:0043062 extracellular structure organization 6/83 302/18722 0.00223642921631063 0.0732429856710301 ADAMTSL4/SPINT1/APP/TGFBI/ENG/COL14A1 6 GO:0009132 nucleoside diphosphate metabolic process 4/83 124/18722 0.00225043846484781 0.0732429856710301 LDHA/ALDOA/GAPDH/APP 4 GO:0045229 external encapsulating structure organization 6/83 304/18722 0.00231134098599733 0.0732429856710301 ADAMTSL4/SPINT1/APP/TGFBI/ENG/COL14A1 6 GO:0090287 regulation of cellular response to growth factor stimulus 6/83 304/18722 0.00231134098599733 0.0732429856710301 FBN2/PEG10/HTRA1/FSTL3/ENG/SEMA6A 6 GO:0045637 regulation of myeloid cell differentiation 5/83 210/18722 0.00242008537155382 0.074073237709249 CSF3R/JUN/PRKDC/ISG15/FSTL3 5 GO:0072521 purine-containing compound metabolic process 7/83 416/18722 0.00247537000248556 0.074073237709249 LDHA/ALDOA/SLC26A2/GAPDH/APP/PARP1/ACSS1 7 GO:0040014 regulation of multicellular organism growth 3/83 61/18722 0.00251251242643281 0.074073237709249 PLAC8/IGF2/APP 3 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 4/83 128/18722 0.00252516013375016 0.074073237709249 FBN2/PEG10/HTRA1/ENG 4 GO:0060033 anatomical structure regression 2/83 17/18722 0.00252914313958119 0.074073237709249 FLT1/LRP5 2 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 4/83 131/18722 0.00274574627438569 0.0780518757115815 FBN2/PEG10/HTRA1/FSTL3 4 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 4/83 131/18722 0.00274574627438569 0.0780518757115815 FBN2/PEG10/HTRA1/ENG 4 GO:0043010 camera-type eye development 6/83 322/18722 0.00307377150032637 0.0861101494221866 FBN2/FLT1/TENM3/SERPINF1/ATP2B1/LRP5 6 GO:0007389 pattern specification process 7/83 436/18722 0.00321177745709636 0.0873222995711291 WLS/NRP2/PRKDC/LRP5/PBX1/ADGRG1/ENG 7 GO:0060562 epithelial tube morphogenesis 6/83 325/18722 0.00321720008158155 0.0873222995711291 SPINT1/LGR5/LRP5/PBX1/MET/ENG 6 GO:0050673 epithelial cell proliferation 7/83 437/18722 0.00325256366741919 0.0873222995711291 IGF2/FLT1/HTRA1/NRP2/PRKDC/LGR5/SERPINF1 7 GO:0071241 cellular response to inorganic substance 5/83 226/18722 0.00331830198209957 0.0878668182383353 JUN/APP/SERPINF1/PARP1/FSTL3 5 GO:0003002 regionalization 6/83 331/18722 0.00351901176784317 0.0919222938816331 WLS/NRP2/PRKDC/LRP5/PBX1/ADGRG1 6 GO:0009314 response to radiation 7/83 456/18722 0.00410560948551567 0.10581524180669 JUN/PRKDC/ADIRF/APP/LRP5/PARP1/DHX36 7 GO:0035924 cellular response to vascular endothelial growth factor stimulus 3/83 73/18722 0.00417971540055216 0.106307761437728 FLT1/NRP2/SEMA6A 3 GO:0002181 cytoplasmic translation 4/83 148/18722 0.00424944834630648 0.106677709784551 RPS21/RPS29/DHX36/RPL37A 4 GO:1903201 regulation of oxidative stress-induced cell death 3/83 74/18722 0.0043425342059347 0.107616905385536 PAGE4/PARP1/MET 3 GO:0048754 branching morphogenesis of an epithelial tube 4/83 151/18722 0.00456257895250587 0.111638798926504 LRP5/PBX1/MET/ENG 4 GO:0030325 adrenal gland development 2/83 23/18722 0.00462455823761582 0.111657396410579 PBX1/FSTL3 2 GO:0045861 negative regulation of proteolysis 6/83 351/18722 0.00467886658523378 0.111657396410579 APLP2/SPINT1/GAPDH/APP/SERPINF1/SERPINE2 6 GO:0051402 neuron apoptotic process 5/83 246/18722 0.004751890468857 0.112017125320739 JUN/GAPDH/APP/EGLN3/PARP1 5 GO:0031016 pancreas development 3/83 77/18722 0.00485392213005009 0.1130437527396 IGF2/WLS/MET 3 GO:0003148 outflow tract septum morphogenesis 2/83 24/18722 0.00503051894078033 0.113738596025572 NRP2/ENG 2 GO:0030500 regulation of bone mineralization 3/83 78/18722 0.00503211256605215 0.113738596025572 FBN2/ISG15/ATP2B1 3 GO:0001764 neuron migration 4/83 156/18722 0.00511841325700381 0.113738596025572 NRP2/TUBB2A/ADGRG1/SEMA6A 4 GO:0001667 ameboidal-type cell migration 7/83 475/18722 0.00511911942794868 0.113738596025572 PDLIM1/NRP2/S100P/SERPINF1/LRP5/MET/SEMA6A 7 GO:1901653 cellular response to peptide 6/83 359/18722 0.00521406053576859 0.11453157972319 IGF2/PRKDC/CYP11A1/APP/ATP2B1/PARP1 6 GO:0070997 neuron death 6/83 361/18722 0.00535461610069554 0.116297448569039 JUN/GAPDH/APP/SERPINF1/EGLN3/PARP1 6 GO:0060706 cell differentiation involved in embryonic placenta development 2/83 25/18722 0.00545229501973675 0.117103180812791 KRT19/KRT8 2 GO:0050767 regulation of neurogenesis 6/83 364/18722 0.00557064599771724 0.117455057930876 SPINT1/ASCL2/SERPINF1/SERPINE2/DHX36/SEMA6A 6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 3/83 81/18722 0.00559020451610997 0.117455057930876 FBN2/PEG10/HTRA1 3 GO:0060669 embryonic placenta morphogenesis 2/83 26/18722 0.00588974172942798 0.122417965193379 IGF2/SPINT1 2 GO:0009117 nucleotide metabolic process 7/83 489/18722 0.00597906787798151 0.12295253412913 LDHA/ALDOA/SLC26A2/GAPDH/APP/PARP1/ACSS1 7 GO:0006091 generation of precursor metabolites and energy 7/83 490/18722 0.00604439192237779 0.122987469325855 LDHA/ALDOA/IGF2/AGL/GAPDH/APP/ACSS1 7 GO:0071772 response to BMP 4/83 165/18722 0.00623015807224549 0.123285398509602 HTRA1/SPINT1/FSTL3/ENG 4 GO:0071773 cellular response to BMP stimulus 4/83 165/18722 0.00623015807224549 0.123285398509602 HTRA1/SPINT1/FSTL3/ENG 4 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 2/83 27/18722 0.00634271527034251 0.123285398509602 APP/PBX1 2 GO:0033688 regulation of osteoblast proliferation 2/83 27/18722 0.00634271527034251 0.123285398509602 ITGAV/LRP5 2 GO:0032868 response to insulin 5/83 264/18722 0.00637793060060023 0.123285398509602 IGF2/PRKDC/TNFSF10/ATP2B1/PARP1 5 GO:0051346 negative regulation of hydrolase activity 6/83 379/18722 0.00674789614133012 0.128335975606007 APLP2/SPINT1/GAPDH/APP/SERPINF1/SERPINE2 6 GO:0009152 purine ribonucleotide biosynthetic process 4/83 169/18722 0.00677199664346233 0.128335975606007 ALDOA/SLC26A2/PARP1/ACSS1 4 GO:0050678 regulation of epithelial cell proliferation 6/83 381/18722 0.00691753818739165 0.129821372002214 IGF2/FLT1/HTRA1/NRP2/PRKDC/SERPINF1 6 GO:1900407 regulation of cellular response to oxidative stress 3/83 89/18722 0.00725482309406499 0.134842048469496 PAGE4/PARP1/MET 3 GO:0002028 regulation of sodium ion transport 3/83 90/18722 0.00748130614648884 0.137727283630123 UTRN/SERPINE2/FXYD5 3 GO:0046034 ATP metabolic process 5/83 277/18722 0.00777222334255792 0.140790560033998 LDHA/ALDOA/GAPDH/APP/PARP1 5 GO:1902751 positive regulation of cell cycle G2/M phase transition 2/83 30/18722 0.0077933729558395 0.140790560033998 APP/PBX1 2 GO:0051591 response to cAMP 3/83 93/18722 0.0081857413816618 0.14650961195141 LDHA/JUN/APP 3 GO:2000144 positive regulation of DNA-templated transcription, initiation 2/83 31/18722 0.00830703454994691 0.147316493440802 JUN/DHX36 2 GO:0032479 regulation of type I interferon production 3/83 95/18722 0.00867635516611199 0.148513532550898 GAPDH/ISG15/DHX36 3 GO:0032606 type I interferon production 3/83 95/18722 0.00867635516611199 0.148513532550898 GAPDH/ISG15/DHX36 3 GO:0036473 cell death in response to oxidative stress 3/83 95/18722 0.00867635516611199 0.148513532550898 PAGE4/PARP1/MET 3 GO:0009260 ribonucleotide biosynthetic process 4/83 182/18722 0.00874642622715246 0.148513532550898 ALDOA/SLC26A2/PARP1/ACSS1 4 GO:0033687 osteoblast proliferation 2/83 32/18722 0.00883551797379887 0.148513532550898 ITGAV/LRP5 2 GO:1901532 regulation of hematopoietic progenitor cell differentiation 2/83 32/18722 0.00883551797379887 0.148513532550898 PRKDC/DHX36 2 GO:0030510 regulation of BMP signaling pathway 3/83 96/18722 0.00892800725651612 0.148774465748669 HTRA1/FSTL3/ENG 3 GO:0070167 regulation of biomineral tissue development 3/83 97/18722 0.0091839097859185 0.149634439741726 FBN2/ISG15/ATP2B1 3 GO:0071375 cellular response to peptide hormone stimulus 5/83 290/18722 0.00936640576625775 0.149634439741726 IGF2/PRKDC/CYP11A1/ATP2B1/PARP1 5 GO:0045648 positive regulation of erythrocyte differentiation 2/83 33/18722 0.00937868498928542 0.149634439741726 PRKDC/ISG15 2 GO:0046685 response to arsenic-containing substance 2/83 33/18722 0.00937868498928542 0.149634439741726 SERPINF1/DHX36 2 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 4/83 186/18722 0.00942211252555934 0.149634439741726 WLS/TNFSF10/GAPDH/DHX36 4 GO:1902882 regulation of response to oxidative stress 3/83 98/18722 0.00944407741773956 0.149634439741726 PAGE4/PARP1/MET 3 GO:0110149 regulation of biomineralization 3/83 99/18722 0.00970852436753106 0.152573801645834 FBN2/ISG15/ATP2B1 3 GO:0048261 negative regulation of receptor-mediated endocytosis 2/83 34/18722 0.00993639826681118 0.153656462797968 LRPAP1/ITGAV 2 GO:0048536 spleen development 2/83 34/18722 0.00993639826681118 0.153656462797968 PRKDC/PBX1 2 GO:0046390 ribose phosphate biosynthetic process 4/83 190/18722 0.0101309924380197 0.155422288751524 ALDOA/SLC26A2/PARP1/ACSS1 4 GO:0006164 purine nucleotide biosynthetic process 4/83 191/18722 0.010313469975895 0.156975885538622 ALDOA/SLC26A2/PARP1/ACSS1 4 GO:0010720 positive regulation of cell development 5/83 298/18722 0.0104524980409027 0.157464897889641 PRKDC/SPINT1/SERPINF1/SERPINE2/DHX36 5 GO:0000460 maturation of 5.8S rRNA 2/83 35/18722 0.0105085213801157 0.157464897889641 RPS21/PRKDC 2 GO:0014013 regulation of gliogenesis 3/83 103/18722 0.0108093742364943 0.159343397442333 SPINT1/ASCL2/SERPINE2 3 GO:0045639 positive regulation of myeloid cell differentiation 3/83 103/18722 0.0108093742364943 0.159343397442333 JUN/PRKDC/ISG15 3 GO:0042063 gliogenesis 5/83 301/18722 0.0108811838915613 0.159343397442333 SPINT1/ASCL2/APP/SERPINE2/ADGRG1 5 GO:0051385 response to mineralocorticoid 2/83 36/18722 0.0110949188011209 0.161251714605765 ATP2B1/PARP1 2 GO:0048846 axon extension involved in axon guidance 2/83 37/18722 0.0116954558948059 0.167461601812294 NRP2/SEMA6A 2 GO:1902284 neuron projection extension involved in neuron projection guidance 2/83 37/18722 0.0116954558948059 0.167461601812294 NRP2/SEMA6A 2 GO:0072522 purine-containing compound biosynthetic process 4/83 200/18722 0.0120523107739293 0.171302328867686 ALDOA/SLC26A2/PARP1/ACSS1 4 GO:0009952 anterior/posterior pattern specification 4/83 201/18722 0.0122564026897384 0.172931579556674 WLS/PRKDC/LRP5/PBX1 4 GO:0032869 cellular response to insulin stimulus 4/83 203/18722 0.012671220449645 0.177373283562918 IGF2/PRKDC/ATP2B1/PARP1 4 GO:0048259 regulation of receptor-mediated endocytosis 3/83 110/18722 0.0129035066583611 0.177373283562918 LRPAP1/ITGAV/AAK1 3 GO:0007618 mating 2/83 39/18722 0.0129384149948522 0.177373283562918 APP/SERPINE2 2 GO:0045785 positive regulation of cell adhesion 6/83 437/18722 0.0130319790212251 0.177373283562918 IGF2/UTRN/EBI3/ITGAV/FSTL3/ADGRG1 6 GO:0060348 bone development 4/83 205/18722 0.0130949377385804 0.177373283562918 PAPPA2/LRP5/ENG/BBX 4 GO:0090288 negative regulation of cellular response to growth factor stimulus 3/83 111/18722 0.0132202573360436 0.177373283562918 HTRA1/FSTL3/SEMA6A 3 GO:0048863 stem cell differentiation 4/83 206/18722 0.0133101537268016 0.177373283562918 NRP2/PRKDC/DHX36/SEMA6A 4 GO:0009141 nucleoside triphosphate metabolic process 3/83 112/18722 0.013541433406673 0.177373283562918 ALDOA/SMPDL3A/PARP1 3 GO:0007339 binding of sperm to zona pellucida 2/83 40/18722 0.0135805721507045 0.177373283562918 ALDOA/LY6K 2 GO:2000142 regulation of DNA-templated transcription, initiation 2/83 40/18722 0.0135805721507045 0.177373283562918 JUN/DHX36 2 GO:2000781 positive regulation of double-strand break repair 2/83 40/18722 0.0135805721507045 0.177373283562918 PRKDC/PARP1 2 GO:0002573 myeloid leukocyte differentiation 4/83 208/18722 0.0137473396387999 0.178346359206713 JUN/APP/PARP1/FSTL3 4 GO:0051960 regulation of nervous system development 6/83 443/18722 0.0138583537601657 0.178587985456002 SPINT1/ASCL2/SERPINF1/SERPINE2/DHX36/SEMA6A 6 GO:0022407 regulation of cell-cell adhesion 6/83 448/18722 0.0145745558283063 0.182357581862342 IGF2/TENM3/EBI3/SERPINE2/FSTL3/FXYD5 6 GO:0030326 embryonic limb morphogenesis 3/83 116/18722 0.0148705540762972 0.182357581862342 FBN2/LRP5/PBX1 3 GO:0031123 RNA 3'-end processing 3/83 116/18722 0.0148705540762972 0.182357581862342 RPS21/APP/DHX36 3 GO:0035113 embryonic appendage morphogenesis 3/83 116/18722 0.0148705540762972 0.182357581862342 FBN2/LRP5/PBX1 3 GO:0035019 somatic stem cell population maintenance 2/83 42/18722 0.0149055861015261 0.182357581862342 ASCL2/LRP5 2 GO:0045214 sarcomere organization 2/83 42/18722 0.0149055861015261 0.182357581862342 KRT19/KRT8 2 GO:0045687 positive regulation of glial cell differentiation 2/83 42/18722 0.0149055861015261 0.182357581862342 SPINT1/SERPINE2 2 GO:2001222 regulation of neuron migration 2/83 42/18722 0.0149055861015261 0.182357581862342 ADGRG1/SEMA6A 2 GO:0045840 positive regulation of mitotic nuclear division 2/83 43/18722 0.0155881832680042 0.188027371042243 IGF2/LRP5 2 GO:0061383 trabecula morphogenesis 2/83 43/18722 0.0155881832680042 0.188027371042243 FBN2/ENG 2 GO:0048638 regulation of developmental growth 5/83 330/18722 0.0156608415612008 0.188027371042243 PLAC8/IGF2/PRKDC/APP/SEMA6A 5 GO:0030282 bone mineralization 3/83 119/18722 0.0159142355053608 0.188892061590255 FBN2/ISG15/ATP2B1 3 GO:0007346 regulation of mitotic cell cycle 6/83 457/18722 0.0159283011066795 0.188892061590255 IGF2/PRKDC/BTG1/APP/LRP5/PBX1 6 GO:0051897 positive regulation of protein kinase B signaling 3/83 120/18722 0.0162710857780428 0.189620339368345 IGF2/MET/ENG 3 GO:0005978 glycogen biosynthetic process 2/83 44/18722 0.0162840022427032 0.189620339368345 IGF2/AGL 2 GO:0009250 glucan biosynthetic process 2/83 44/18722 0.0162840022427032 0.189620339368345 IGF2/AGL 2 GO:0035272 exocrine system development 2/83 45/18722 0.0169929153537491 0.194362753720692 IGF2/WLS 2 GO:0048538 thymus development 2/83 45/18722 0.0169929153537491 0.194362753720692 PRKDC/PBX1 2 GO:1904646 cellular response to amyloid-beta 2/83 45/18722 0.0169929153537491 0.194362753720692 APP/PARP1 2 GO:0007568 aging 5/83 339/18722 0.0173904798357336 0.196583611242532 JUN/PRKDC/APP/SERPINF1/ATP2B1 5 GO:0048545 response to steroid hormone 5/83 339/18722 0.0173904798357336 0.196583611242532 AGL/SERPINF1/ATP2B1/PARP1/ENG 5 GO:0050769 positive regulation of neurogenesis 4/83 225/18722 0.0178349187061685 0.200435452668743 SPINT1/SERPINF1/SERPINE2/DHX36 4 GO:0045765 regulation of angiogenesis 5/83 342/18722 0.0179941389477872 0.201055899341461 FLT1/BTG1/SERPINF1/ENG/SEMA6A 5 GO:0045646 regulation of erythrocyte differentiation 2/83 47/18722 0.0184495175331486 0.202630212452138 PRKDC/ISG15 2 GO:0101023 vascular endothelial cell proliferation 2/83 47/18722 0.0184495175331486 0.202630212452138 IGF2/FLT1 2 GO:1905562 regulation of vascular endothelial cell proliferation 2/83 47/18722 0.0184495175331486 0.202630212452138 IGF2/FLT1 2 GO:0045444 fat cell differentiation 4/83 229/18722 0.0188955042653398 0.206355987259332 PLAC8/ADIRF/LRP5/ARL4A 4 GO:0035036 sperm-egg recognition 2/83 48/18722 0.0191969554789569 0.207801282008287 ALDOA/LY6K 2 GO:1901342 regulation of vasculature development 5/83 348/18722 0.0192428502221849 0.207801282008287 FLT1/BTG1/SERPINF1/ENG/SEMA6A 5 GO:0009409 response to cold 2/83 49/18722 0.019956985306374 0.212764554720382 PLAC8/ATP2B1 2 GO:0030225 macrophage differentiation 2/83 49/18722 0.019956985306374 0.212764554720382 APP/PARP1 2 GO:0006352 DNA-templated transcription, initiation 3/83 130/18722 0.0200871373220632 0.212764554720382 JUN/TFAM/DHX36 3 GO:0016049 cell growth 6/83 482/18722 0.0201427384965493 0.212764554720382 NRP2/BTG1/APP/PAPPA2/SERPINE2/SEMA6A 6 GO:0000723 telomere maintenance 3/83 131/18722 0.0204935761747432 0.214130177004209 PRKDC/PARP1/DHX36 3 GO:0046683 response to organophosphorus 3/83 131/18722 0.0204935761747432 0.214130177004209 LDHA/JUN/APP 3 GO:0050873 brown fat cell differentiation 2/83 50/18722 0.0207294835357868 0.214938704447992 PLAC8/ARL4A 2 GO:0090068 positive regulation of cell cycle process 4/83 236/18722 0.0208442942554007 0.214938704447992 IGF2/APP/LRP5/PBX1 4 GO:0035264 multicellular organism growth 3/83 132/18722 0.0209045403187908 0.214938704447992 PLAC8/IGF2/APP 3 GO:0019318 hexose metabolic process 4/83 237/18722 0.021132417962413 0.216132084239917 ALDOA/IGF2/GAPDH/LRP5 4 GO:0034765 regulation of ion transmembrane transport 6/83 491/18722 0.0218303364366959 0.222094949116491 CLIC3/TCAF1/UTRN/KCNN4/APP/FXYD5 6 GO:0030514 negative regulation of BMP signaling pathway 2/83 52/18722 0.0223113953977626 0.225800666512435 HTRA1/FSTL3 2 GO:0051098 regulation of binding 5/83 363/18722 0.0226113788184881 0.227644766959049 LRPAP1/JUN/APP/PARP1/MET 5 GO:0008203 cholesterol metabolic process 3/83 137/18722 0.0230272817722464 0.227808327569615 CYP11A1/APP/LRP5 3 GO:0050714 positive regulation of protein secretion 3/83 137/18722 0.0230272817722464 0.227808327569615 WLS/MYH10/KCNN4 3 GO:0045806 negative regulation of endocytosis 2/83 53/18722 0.023120566172535 0.227808327569615 LRPAP1/ITGAV 2 GO:1903202 negative regulation of oxidative stress-induced cell death 2/83 53/18722 0.023120566172535 0.227808327569615 PAGE4/MET 2 GO:0035107 appendage morphogenesis 3/83 138/18722 0.0234654182561451 0.227808327569615 FBN2/LRP5/PBX1 3 GO:0035108 limb morphogenesis 3/83 138/18722 0.0234654182561451 0.227808327569615 FBN2/LRP5/PBX1 3 GO:0001701 in utero embryonic development 5/83 367/18722 0.023570442583509 0.227808327569615 KRT19/IGF2/KRT8/SPINT1/ASCL2 5 GO:1903706 regulation of hemopoiesis 5/83 367/18722 0.023570442583509 0.227808327569615 CSF3R/JUN/PRKDC/ISG15/FSTL3 5 GO:0071692 protein localization to extracellular region 5/83 368/18722 0.0238142702713086 0.229019823056913 FBN2/WLS/MYH10/KCNN4/LRP5 5 GO:0070839 metal ion export 2/83 54/18722 0.0239417196243266 0.229105663533779 ATP2B1/SLC40A1 2 GO:0001755 neural crest cell migration 2/83 55/18722 0.0247747363467741 0.232776375845855 NRP2/SEMA6A 2 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 4/83 249/18722 0.024782092208866 0.232776375845855 WLS/TNFSF10/GAPDH/DHX36 4 GO:0045926 negative regulation of growth 4/83 249/18722 0.024782092208866 0.232776375845855 PLAC8/BTG1/SERPINE2/SEMA6A 4 GO:0008584 male gonad development 3/83 141/18722 0.0248070012541366 0.232776375845855 TNFSF10/FSTL3/ADGRG1 3 GO:0010038 response to metal ion 5/83 373/18722 0.0250579557426458 0.23399530652432 JUN/APP/SERPINF1/PARP1/FSTL3 5 GO:0046546 development of primary male sexual characteristics 3/83 142/18722 0.0252632505183265 0.234703739905812 TNFSF10/FSTL3/ADGRG1 3 GO:0010332 response to gamma radiation 2/83 56/18722 0.0256194977341574 0.234703739905812 PRKDC/PARP1 2 GO:0071385 cellular response to glucocorticoid stimulus 2/83 56/18722 0.0256194977341574 0.234703739905812 SERPINF1/ATP2B1 2 GO:1904645 response to amyloid-beta 2/83 56/18722 0.0256194977341574 0.234703739905812 APP/PARP1 2 GO:0009165 nucleotide biosynthetic process 4/83 254/18722 0.0264086147827679 0.23914900744455 ALDOA/SLC26A2/PARP1/ACSS1 4 GO:0006754 ATP biosynthetic process 2/83 57/18722 0.0264758859767893 0.23914900744455 ALDOA/PARP1 2 GO:0051785 positive regulation of nuclear division 2/83 57/18722 0.0264758859767893 0.23914900744455 IGF2/LRP5 2 GO:1901293 nucleoside phosphate biosynthetic process 4/83 256/18722 0.0270768262468359 0.241514252837126 ALDOA/SLC26A2/PARP1/ACSS1 4 GO:0042542 response to hydrogen peroxide 3/83 146/18722 0.0271334822307728 0.241514252837126 LDHA/JUN/MET 3 GO:2000649 regulation of sodium ion transmembrane transporter activity 2/83 58/18722 0.0273437840564274 0.241514252837126 UTRN/FXYD5 2 GO:2000736 regulation of stem cell differentiation 2/83 58/18722 0.0273437840564274 0.241514252837126 PRKDC/DHX36 2 GO:0005996 monosaccharide metabolic process 4/83 257/18722 0.0274147177073399 0.241514252837126 ALDOA/IGF2/GAPDH/LRP5 4 GO:0060041 retina development in camera-type eye 3/83 147/18722 0.0276123382705664 0.241514252837126 SERPINF1/ATP2B1/LRP5 3 GO:1902652 secondary alcohol metabolic process 3/83 147/18722 0.0276123382705664 0.241514252837126 CYP11A1/APP/LRP5 3 GO:0042692 muscle cell differentiation 5/83 384/18722 0.0279397421641354 0.242450912279448 KRT19/IGF2/KRT8/MORF4L2/ENG 5 GO:0014074 response to purine-containing compound 3/83 148/18722 0.0280957084069304 0.242450912279448 LDHA/JUN/APP 3 GO:0051384 response to glucocorticoid 3/83 148/18722 0.0280957084069304 0.242450912279448 AGL/SERPINF1/ATP2B1 3 GO:0001836 release of cytochrome c from mitochondria 2/83 59/18722 0.0282230757417125 0.242467579594357 JUN/TNFSF10 2 GO:0033866 nucleoside bisphosphate biosynthetic process 2/83 60/18722 0.0291136455836292 0.246827530320856 SLC26A2/ACSS1 2 GO:0034030 ribonucleoside bisphosphate biosynthetic process 2/83 60/18722 0.0291136455836292 0.246827530320856 SLC26A2/ACSS1 2 GO:0034033 purine nucleoside bisphosphate biosynthetic process 2/83 60/18722 0.0291136455836292 0.246827530320856 SLC26A2/ACSS1 2 GO:0048592 eye morphogenesis 3/83 151/18722 0.0295728718349843 0.248433996916552 FBN2/TENM3/LRP5 3 GO:0040013 negative regulation of locomotion 5/83 391/18722 0.0298794128385125 0.248433996916552 TCAF1/SERPINF1/ADGRG1/ENG/SEMA6A 5 GO:0071384 cellular response to corticosteroid stimulus 2/83 61/18722 0.0300153789109917 0.248433996916552 SERPINF1/ATP2B1 2 GO:1904356 regulation of telomere maintenance via telomere lengthening 2/83 61/18722 0.0300153789109917 0.248433996916552 PARP1/DHX36 2 GO:0016125 sterol metabolic process 3/83 152/18722 0.0300742655346473 0.248433996916552 CYP11A1/APP/LRP5 3 GO:0030509 BMP signaling pathway 3/83 152/18722 0.0300742655346473 0.248433996916552 HTRA1/FSTL3/ENG 3 GO:0031124 mRNA 3'-end processing 2/83 62/18722 0.0309281618259536 0.253363625963522 APP/DHX36 2 GO:0032412 regulation of ion transmembrane transporter activity 4/83 267/18722 0.0309331690260689 0.253363625963522 TCAF1/UTRN/APP/FXYD5 4 GO:0050708 regulation of protein secretion 4/83 268/18722 0.0312990281979118 0.255278571757652 WLS/MYH10/KCNN4/LRP5 4 GO:0051147 regulation of muscle cell differentiation 3/83 155/18722 0.0316054078997436 0.256694342311783 IGF2/MORF4L2/ENG 3 GO:0030239 myofibril assembly 2/83 63/18722 0.0318518811995403 0.257613750454859 KRT19/KRT8 2 GO:0055002 striated muscle cell development 2/83 64/18722 0.0327864246672062 0.261898055539053 KRT19/KRT8 2 GO:1900076 regulation of cellular response to insulin stimulus 2/83 64/18722 0.0327864246672062 0.261898055539053 IGF2/ATP2B1 2 GO:0051962 positive regulation of nervous system development 4/83 272/18722 0.0327880648941805 0.261898055539053 SPINT1/SERPINF1/SERPINE2/DHX36 4 GO:0032200 telomere organization 3/83 159/18722 0.033709665629504 0.267226797733584 PRKDC/PARP1/DHX36 3 GO:0033692 cellular polysaccharide biosynthetic process 2/83 65/18722 0.0337316806244152 0.267226797733584 IGF2/AGL 2 GO:0010959 regulation of metal ion transport 5/83 406/18722 0.0343180346654718 0.269285996693461 UTRN/KCNN4/ATP2B1/SERPINE2/FXYD5 5 GO:0007548 sex differentiation 4/83 276/18722 0.0343181572764302 0.269285996693461 TNFSF10/PBX1/FSTL3/ADGRG1 4 GO:0014015 positive regulation of gliogenesis 2/83 66/18722 0.0346875382222441 0.269285996693461 SPINT1/SERPINE2 2 GO:0045600 positive regulation of fat cell differentiation 2/83 66/18722 0.0346875382222441 0.269285996693461 ADIRF/LRP5 2 GO:0022898 regulation of transmembrane transporter activity 4/83 278/18722 0.0350986345746065 0.269285996693461 TCAF1/UTRN/APP/FXYD5 4 GO:0043542 endothelial cell migration 4/83 279/18722 0.0354927363591225 0.269285996693461 NRP2/S100P/SERPINF1/MET 4 GO:0010976 positive regulation of neuron projection development 3/83 163/18722 0.0358853042584549 0.269285996693461 TENM3/SERPINF1/DHX36 3 GO:0007249 I-kappaB kinase/NF-kappaB signaling 4/83 281/18722 0.0362886729204222 0.269285996693461 WLS/TNFSF10/GAPDH/DHX36 4 GO:0009206 purine ribonucleoside triphosphate biosynthetic process 2/83 68/18722 0.0366306186959203 0.269285996693461 ALDOA/PARP1 2 GO:0009988 cell-cell recognition 2/83 68/18722 0.0366306186959203 0.269285996693461 ALDOA/LY6K 2 GO:0060411 cardiac septum morphogenesis 2/83 68/18722 0.0366306186959203 0.269285996693461 NRP2/ENG 2 GO:1902305 regulation of sodium ion transmembrane transport 2/83 68/18722 0.0366306186959203 0.269285996693461 UTRN/FXYD5 2 GO:0046661 male sex differentiation 3/83 165/18722 0.0369997692550819 0.269285996693461 TNFSF10/FSTL3/ADGRG1 3 GO:0051146 striated muscle cell differentiation 4/83 283/18722 0.037094928138661 0.269285996693461 KRT19/IGF2/KRT8/MORF4L2 4 GO:0009145 purine nucleoside triphosphate biosynthetic process 2/83 69/18722 0.0376176236127464 0.269285996693461 ALDOA/PARP1 2 GO:0045665 negative regulation of neuron differentiation 2/83 69/18722 0.0376176236127464 0.269285996693461 APP/PBX1 2 GO:0045669 positive regulation of osteoblast differentiation 2/83 69/18722 0.0376176236127464 0.269285996693461 FBN2/LRP5 2 GO:0032102 negative regulation of response to external stimulus 5/83 420/18722 0.0388136924639218 0.269285996693461 HTRA1/SERPINF1/ISG15/SERPINE2/SEMA6A 5 GO:0034599 cellular response to oxidative stress 4/83 288/18722 0.0391557625880308 0.269285996693461 JUN/PAGE4/PARP1/MET 4 GO:0031214 biomineral tissue development 3/83 169/18722 0.0392817163713652 0.269285996693461 FBN2/ISG15/ATP2B1 3 GO:0110148 biomineralization 3/83 171/18722 0.0404490789475733 0.269285996693461 FBN2/ISG15/ATP2B1 3 GO:0000271 polysaccharide biosynthetic process 2/83 72/18722 0.0406392048326712 0.269285996693461 IGF2/AGL 2 GO:0005977 glycogen metabolic process 2/83 72/18722 0.0406392048326712 0.269285996693461 IGF2/AGL 2 GO:0032729 positive regulation of interferon-gamma production 2/83 72/18722 0.0406392048326712 0.269285996693461 EBI3/ISG15 2 GO:0051057 positive regulation of small GTPase mediated signal transduction 2/83 72/18722 0.0406392048326712 0.269285996693461 ITGAV/ADGRG1 2 GO:0007219 Notch signaling pathway 3/83 172/18722 0.0410393297786108 0.269285996693461 KRT19/APP/AAK1 3 GO:0048736 appendage development 3/83 172/18722 0.0410393297786108 0.269285996693461 FBN2/LRP5/PBX1 3 GO:0060173 limb development 3/83 172/18722 0.0410393297786108 0.269285996693461 FBN2/LRP5/PBX1 3 GO:0051099 positive regulation of binding 3/83 173/18722 0.0416339492332084 0.269285996693461 APP/PARP1/MET 3 GO:0006073 cellular glucan metabolic process 2/83 73/18722 0.0416662327039985 0.269285996693461 IGF2/AGL 2 GO:0042274 ribosomal small subunit biogenesis 2/83 73/18722 0.0416662327039985 0.269285996693461 RPS21/PRKDC 2 GO:0044042 glucan metabolic process 2/83 73/18722 0.0416662327039985 0.269285996693461 IGF2/AGL 2 GO:0045739 positive regulation of DNA repair 2/83 73/18722 0.0416662327039985 0.269285996693461 PRKDC/PARP1 2 GO:0007584 response to nutrient 3/83 174/18722 0.0422329287719311 0.269285996693461 LDHA/AGL/ATP2B1 3 GO:0003151 outflow tract morphogenesis 2/83 74/18722 0.0427030021067225 0.269285996693461 NRP2/ENG 2 GO:0009201 ribonucleoside triphosphate biosynthetic process 2/83 74/18722 0.0427030021067225 0.269285996693461 ALDOA/PARP1 2 GO:0003056 regulation of vascular associated smooth muscle contraction 1/83 10/18722 0.0434690555569142 0.269285996693461 ATP2B1 1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 1/83 10/18722 0.0434690555569142 0.269285996693461 EGLN3 1 GO:0019532 oxalate transport 1/83 10/18722 0.0434690555569142 0.269285996693461 SLC26A2 1 GO:0021562 vestibulocochlear nerve development 1/83 10/18722 0.0434690555569142 0.269285996693461 NRP2 1 GO:0030388 fructose 1,6-bisphosphate metabolic process 1/83 10/18722 0.0434690555569142 0.269285996693461 ALDOA 1 GO:0031125 rRNA 3'-end processing 1/83 10/18722 0.0434690555569142 0.269285996693461 RPS21 1 GO:0032025 response to cobalt ion 1/83 10/18722 0.0434690555569142 0.269285996693461 SERPINF1 1 GO:0035907 dorsal aorta development 1/83 10/18722 0.0434690555569142 0.269285996693461 ENG 1 GO:0036363 transforming growth factor beta activation 1/83 10/18722 0.0434690555569142 0.269285996693461 ITGAV 1 GO:0040015 negative regulation of multicellular organism growth 1/83 10/18722 0.0434690555569142 0.269285996693461 PLAC8 1 GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 1/83 10/18722 0.0434690555569142 0.269285996693461 SERPINF1 1 GO:0061299 retina vasculature morphogenesis in camera-type eye 1/83 10/18722 0.0434690555569142 0.269285996693461 LRP5 1 GO:0090647 modulation of age-related behavioral decline 1/83 10/18722 0.0434690555569142 0.269285996693461 APP 1 GO:0097084 vascular associated smooth muscle cell development 1/83 10/18722 0.0434690555569142 0.269285996693461 ENG 1 GO:0098885 modification of postsynaptic actin cytoskeleton 1/83 10/18722 0.0434690555569142 0.269285996693461 MYH10 1 GO:1903867 extraembryonic membrane development 1/83 10/18722 0.0434690555569142 0.269285996693461 HTRA1 1 GO:1990535 neuron projection maintenance 1/83 10/18722 0.0434690555569142 0.269285996693461 APP 1 GO:2001223 negative regulation of neuron migration 1/83 10/18722 0.0434690555569142 0.269285996693461 ADGRG1 1 GO:0008088 axo-dendritic transport 2/83 75/18722 0.0437494087984151 0.269285996693461 ARMCX3/APP 2 GO:0043627 response to estrogen 2/83 75/18722 0.0437494087984151 0.269285996693461 LDHA/KRT19 2 GO:0045913 positive regulation of carbohydrate metabolic process 2/83 75/18722 0.0437494087984151 0.269285996693461 IGF2/APP 2 GO:0061333 renal tubule morphogenesis 2/83 75/18722 0.0437494087984151 0.269285996693461 LGR5/PBX1 2 GO:0009266 response to temperature stimulus 3/83 178/18722 0.0446722705392956 0.269285996693461 PLAC8/ATP2B1/DHX36 3 GO:0045685 regulation of glial cell differentiation 2/83 76/18722 0.0448053492495617 0.269285996693461 SPINT1/SERPINE2 2 GO:0140115 export across plasma membrane 2/83 76/18722 0.0448053492495617 0.269285996693461 ATP2B1/SLC40A1 2 GO:0072001 renal system development 4/83 302/18722 0.0452700889926856 0.269285996693461 LGR5/SERPINF1/PBX1/FSTL3 4 GO:0001936 regulation of endothelial cell proliferation 3/83 179/18722 0.0452929160016159 0.269285996693461 IGF2/FLT1/NRP2 3 GO:0007162 negative regulation of cell adhesion 4/83 303/18722 0.0457262295542647 0.269285996693461 SERPINE2/TGFBI/FXYD5/SEMA6A 4 GO:0051222 positive regulation of protein transport 4/83 303/18722 0.0457262295542647 0.269285996693461 WLS/TCAF1/MYH10/KCNN4 4 GO:0021675 nerve development 2/83 77/18722 0.0458707206394153 0.269285996693461 NRP2/SERPINE2 2 GO:0045766 positive regulation of angiogenesis 3/83 181/18722 0.0465471122557974 0.269285996693461 FLT1/BTG1/ENG 3 GO:1904018 positive regulation of vasculature development 3/83 181/18722 0.0465471122557974 0.269285996693461 FLT1/BTG1/ENG 3 GO:0034637 cellular carbohydrate biosynthetic process 2/83 78/18722 0.0469454208518723 0.269285996693461 IGF2/AGL 2 GO:0001666 response to hypoxia 4/83 307/18722 0.0475766394666318 0.269285996693461 LDHA/PDLIM1/ASCL2/EGLN3 4 GO:0001967 suckling behavior 1/83 11/18722 0.0477118980317314 0.269285996693461 APP 1 GO:0002732 positive regulation of dendritic cell cytokine production 1/83 11/18722 0.0477118980317314 0.269285996693461 DHX36 1 GO:0014010 Schwann cell proliferation 1/83 11/18722 0.0477118980317314 0.269285996693461 ASCL2 1 GO:0021561 facial nerve development 1/83 11/18722 0.0477118980317314 0.269285996693461 NRP2 1 GO:0021604 cranial nerve structural organization 1/83 11/18722 0.0477118980317314 0.269285996693461 NRP2 1 GO:0021610 facial nerve morphogenesis 1/83 11/18722 0.0477118980317314 0.269285996693461 NRP2 1 GO:0031442 positive regulation of mRNA 3'-end processing 1/83 11/18722 0.0477118980317314 0.269285996693461 DHX36 1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway 1/83 11/18722 0.0477118980317314 0.269285996693461 PARP1 1 GO:0033210 leptin-mediated signaling pathway 1/83 11/18722 0.0477118980317314 0.269285996693461 EBI3 1 GO:0034650 cortisol metabolic process 1/83 11/18722 0.0477118980317314 0.269285996693461 CYP11A1 1 GO:0035581 sequestering of extracellular ligand from receptor 1/83 11/18722 0.0477118980317314 0.269285996693461 FBN2 1 GO:0045657 positive regulation of monocyte differentiation 1/83 11/18722 0.0477118980317314 0.269285996693461 JUN 1 GO:0060767 epithelial cell proliferation involved in prostate gland development 1/83 11/18722 0.0477118980317314 0.269285996693461 SERPINF1 1 GO:1900222 negative regulation of amyloid-beta clearance 1/83 11/18722 0.0477118980317314 0.269285996693461 LRPAP1 1 GO:1903961 positive regulation of anion transmembrane transport 1/83 11/18722 0.0477118980317314 0.269285996693461 TCAF1 1 GO:1904181 positive regulation of membrane depolarization 1/83 11/18722 0.0477118980317314 0.269285996693461 PARP1 1 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 2/83 79/18722 0.0480293484713699 0.269285996693461 PRKDC/DHX36 2 GO:0055001 muscle cell development 3/83 184/18722 0.0484605206530434 0.269285996693461 KRT19/KRT8/ENG 3 GO:0022604 regulation of cell morphogenesis 4/83 309/18722 0.0485173424030626 0.269285996693461 ALDOA/PRKDC/MYH10/DHX36 4 GO:0032409 regulation of transporter activity 4/83 310/18722 0.0489915651936128 0.269285996693461 TCAF1/UTRN/APP/FXYD5 4 GO:0007369 gastrulation 3/83 185/18722 0.0491068462177545 0.269285996693461 WLS/ITGAV/LRP5 3 GO:0051896 regulation of protein kinase B signaling 3/83 185/18722 0.0491068462177545 0.269285996693461 IGF2/MET/ENG 3 GO:0001570 vasculogenesis 2/83 80/18722 0.0491224027788064 0.269285996693461 ITGAV/ENG 2 GO:0032204 regulation of telomere maintenance 2/83 80/18722 0.0491224027788064 0.269285996693461 PARP1/DHX36 2 GO:0071478 cellular response to radiation 3/83 186/18722 0.0497574156225446 0.269285996693461 ADIRF/PARP1/DHX36 3 GO:0010833 telomere maintenance via telomere lengthening 2/83 81/18722 0.0502244837474823 0.269285996693461 PARP1/DHX36 2 GO:0014032 neural crest cell development 2/83 81/18722 0.0502244837474823 0.269285996693461 NRP2/SEMA6A 2 GO:0048708 astrocyte differentiation 2/83 81/18722 0.0502244837474823 0.269285996693461 APP/SERPINE2 2 GO:0051149 positive regulation of muscle cell differentiation 2/83 81/18722 0.0502244837474823 0.269285996693461 MORF4L2/ENG 2 GO:0045787 positive regulation of cell cycle 4/83 313/18722 0.0504297057798513 0.269285996693461 IGF2/APP/LRP5/PBX1 4 GO:0030308 negative regulation of cell growth 3/83 188/18722 0.0510712427479523 0.269285996693461 BTG1/SERPINE2/SEMA6A 3 GO:0009205 purine ribonucleoside triphosphate metabolic process 2/83 82/18722 0.0513354920390631 0.269285996693461 ALDOA/PARP1 2 GO:0060395 SMAD protein signal transduction 2/83 82/18722 0.0513354920390631 0.269285996693461 JUN/PARP1 2 GO:0000012 single strand break repair 1/83 12/18722 0.0519361464665218 0.269285996693461 PARP1 1 GO:0002328 pro-B cell differentiation 1/83 12/18722 0.0519361464665218 0.269285996693461 PRKDC 1 GO:0007320 insemination 1/83 12/18722 0.0519361464665218 0.269285996693461 SERPINE2 1 GO:0007614 short-term memory 1/83 12/18722 0.0519361464665218 0.269285996693461 SERPINF1 1 GO:0010623 programmed cell death involved in cell development 1/83 12/18722 0.0519361464665218 0.269285996693461 PRKDC 1 GO:0021978 telencephalon regionalization 1/83 12/18722 0.0519361464665218 0.269285996693461 ADGRG1 1 GO:0031953 negative regulation of protein autophosphorylation 1/83 12/18722 0.0519361464665218 0.269285996693461 ENG 1 GO:0032926 negative regulation of activin receptor signaling pathway 1/83 12/18722 0.0519361464665218 0.269285996693461 FSTL3 1 GO:0046541 saliva secretion 1/83 12/18722 0.0519361464665218 0.269285996693461 KCNN4 1 GO:0061430 bone trabecula morphogenesis 1/83 12/18722 0.0519361464665218 0.269285996693461 FBN2 1 GO:0070213 protein auto-ADP-ribosylation 1/83 12/18722 0.0519361464665218 0.269285996693461 PARP1 1 GO:0071287 cellular response to manganese ion 1/83 12/18722 0.0519361464665218 0.269285996693461 APP 1 GO:0072520 seminiferous tubule development 1/83 12/18722 0.0519361464665218 0.269285996693461 ADGRG1 1 GO:0090331 negative regulation of platelet aggregation 1/83 12/18722 0.0519361464665218 0.269285996693461 SERPINE2 1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress 1/83 12/18722 0.0519361464665218 0.269285996693461 JUN 1 GO:1901298 regulation of hydrogen peroxide-mediated programmed cell death 1/83 12/18722 0.0519361464665218 0.269285996693461 MET 1 GO:1990034 calcium ion export across plasma membrane 1/83 12/18722 0.0519361464665218 0.269285996693461 ATP2B1 1 GO:0051899 membrane depolarization 2/83 83/18722 0.052455328999564 0.269285996693461 JUN/PARP1 2 GO:0008202 steroid metabolic process 4/83 319/18722 0.0533754943863009 0.269285996693461 CYP11A1/APP/LRP5/PBX1 4 GO:1901214 regulation of neuron death 4/83 319/18722 0.0533754943863009 0.269285996693461 JUN/SERPINF1/EGLN3/PARP1 4 GO:1904951 positive regulation of establishment of protein localization 4/83 319/18722 0.0533754943863009 0.269285996693461 WLS/TCAF1/MYH10/KCNN4 4 GO:0006112 energy reserve metabolic process 2/83 84/18722 0.0535838966553558 0.269285996693461 IGF2/AGL 2 GO:1900542 regulation of purine nucleotide metabolic process 2/83 84/18722 0.0535838966553558 0.269285996693461 APP/PARP1 2 GO:0001935 endothelial cell proliferation 3/83 193/18722 0.0544293057218799 0.269285996693461 IGF2/FLT1/NRP2 3 GO:0009142 nucleoside triphosphate biosynthetic process 2/83 85/18722 0.0547210977091922 0.269285996693461 ALDOA/PARP1 2 GO:2000779 regulation of double-strand break repair 2/83 85/18722 0.0547210977091922 0.269285996693461 PRKDC/PARP1 2 GO:0036293 response to decreased oxygen levels 4/83 322/18722 0.054883059416803 0.269285996693461 LDHA/PDLIM1/ASCL2/EGLN3 4 GO:1901654 response to ketone 3/83 194/18722 0.0551134256839644 0.269285996693461 SERPINF1/ATP2B1/PARP1 3 GO:0006140 regulation of nucleotide metabolic process 2/83 86/18722 0.055866835536258 0.269285996693461 APP/PARP1 2 GO:0014031 mesenchymal cell development 2/83 86/18722 0.055866835536258 0.269285996693461 NRP2/SEMA6A 2 GO:0035023 regulation of Rho protein signal transduction 2/83 86/18722 0.055866835536258 0.269285996693461 MET/ADGRG1 2 GO:0048864 stem cell development 2/83 86/18722 0.055866835536258 0.269285996693461 NRP2/SEMA6A 2 GO:0001886 endothelial cell morphogenesis 1/83 13/18722 0.0561418813592679 0.269285996693461 MET 1 GO:0002638 negative regulation of immunoglobulin production 1/83 13/18722 0.0561418813592679 0.269285996693461 PRKDC 1 GO:0003222 ventricular trabecula myocardium morphogenesis 1/83 13/18722 0.0561418813592679 0.269285996693461 ENG 1 GO:0006000 fructose metabolic process 1/83 13/18722 0.0561418813592679 0.269285996693461 ALDOA 1 GO:0007183 SMAD protein complex assembly 1/83 13/18722 0.0561418813592679 0.269285996693461 PARP1 1 GO:0008298 intracellular mRNA localization 1/83 13/18722 0.0561418813592679 0.269285996693461 DHX36 1 GO:0009143 nucleoside triphosphate catabolic process 1/83 13/18722 0.0561418813592679 0.269285996693461 SMPDL3A 1 GO:0010745 negative regulation of macrophage derived foam cell differentiation 1/83 13/18722 0.0561418813592679 0.269285996693461 ITGAV 1 GO:0010755 regulation of plasminogen activation 1/83 13/18722 0.0561418813592679 0.269285996693461 SERPINE2 1 GO:0016322 neuron remodeling 1/83 13/18722 0.0561418813592679 0.269285996693461 APP 1 GO:0021681 cerebellar granular layer development 1/83 13/18722 0.0561418813592679 0.269285996693461 SERPINE2 1 GO:0021819 layer formation in cerebral cortex 1/83 13/18722 0.0561418813592679 0.269285996693461 ADGRG1 1 GO:0032042 mitochondrial DNA metabolic process 1/83 13/18722 0.0561418813592679 0.269285996693461 PARP1 1 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway 1/83 13/18722 0.0561418813592679 0.269285996693461 PARP1 1 GO:0036302 atrioventricular canal development 1/83 13/18722 0.0561418813592679 0.269285996693461 ENG 1 GO:0042769 DNA damage response, detection of DNA damage 1/83 13/18722 0.0561418813592679 0.269285996693461 PARP1 1 GO:0048012 hepatocyte growth factor receptor signaling pathway 1/83 13/18722 0.0561418813592679 0.269285996693461 MET 1 GO:0048711 positive regulation of astrocyte differentiation 1/83 13/18722 0.0561418813592679 0.269285996693461 SERPINE2 1 GO:0051481 negative regulation of cytosolic calcium ion concentration 1/83 13/18722 0.0561418813592679 0.269285996693461 ATP2B1 1 GO:0060670 branching involved in labyrinthine layer morphogenesis 1/83 13/18722 0.0561418813592679 0.269285996693461 SPINT1 1 GO:0098814 spontaneous synaptic transmission 1/83 13/18722 0.0561418813592679 0.269285996693461 APP 1 GO:1900272 negative regulation of long-term synaptic potentiation 1/83 13/18722 0.0561418813592679 0.269285996693461 APP 1 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance 1/83 13/18722 0.0561418813592679 0.269285996693461 NRP2 1 GO:2001023 regulation of response to drug 1/83 13/18722 0.0561418813592679 0.269285996693461 ADIRF 1 GO:0001819 positive regulation of cytokine production 5/83 467/18722 0.0564572160573278 0.269637168844261 EBI3/GAPDH/APP/ISG15/DHX36 5 GO:0006006 glucose metabolic process 3/83 196/18722 0.0564940783144986 0.269637168844261 IGF2/GAPDH/LRP5 3 GO:1903578 regulation of ATP metabolic process 2/83 87/18722 0.0570210141802384 0.270814792163147 APP/PARP1 2 GO:2000177 regulation of neural precursor cell proliferation 2/83 87/18722 0.0570210141802384 0.270814792163147 SPINT1/ADGRG1 2 GO:0010952 positive regulation of peptidase activity 3/83 197/18722 0.0571905866957009 0.270954421771544 TNFSF10/APP/EGLN3 3 GO:0009144 purine nucleoside triphosphate metabolic process 2/83 88/18722 0.0581835383494099 0.272480778875387 ALDOA/PARP1 2 GO:0009199 ribonucleoside triphosphate metabolic process 2/83 89/18722 0.0593543134127511 0.272480778875387 ALDOA/PARP1 2 GO:0031667 response to nutrient levels 5/83 474/18722 0.0594250102705761 0.272480778875387 LDHA/JUN/AGL/PAGE4/ATP2B1 5 GO:0071214 cellular response to abiotic stimulus 4/83 331/18722 0.0595438212841675 0.272480778875387 ADIRF/PARP1/DHX36/ENG 4 GO:0104004 cellular response to environmental stimulus 4/83 331/18722 0.0595438212841675 0.272480778875387 ADIRF/PARP1/DHX36/ENG 4 GO:0051054 positive regulation of DNA metabolic process 3/83 201/18722 0.0600175444436455 0.272480778875387 PRKDC/PARP1/DHX36 3 GO:0002091 negative regulation of receptor internalization 1/83 14/18722 0.0603291828637403 0.272480778875387 LRPAP1 1 GO:0010421 hydrogen peroxide-mediated programmed cell death 1/83 14/18722 0.0603291828637403 0.272480778875387 MET 1 GO:0034111 negative regulation of homotypic cell-cell adhesion 1/83 14/18722 0.0603291828637403 0.272480778875387 SERPINE2 1 GO:0043922 negative regulation by host of viral transcription 1/83 14/18722 0.0603291828637403 0.272480778875387 JUN 1 GO:0060841 venous blood vessel development 1/83 14/18722 0.0603291828637403 0.272480778875387 ENG 1 GO:0070278 extracellular matrix constituent secretion 1/83 14/18722 0.0603291828637403 0.272480778875387 ENG 1 GO:1902036 regulation of hematopoietic stem cell differentiation 1/83 14/18722 0.0603291828637403 0.272480778875387 PRKDC 1 GO:1905065 positive regulation of vascular associated smooth muscle cell differentiation 1/83 14/18722 0.0603291828637403 0.272480778875387 ENG 1 GO:0034644 cellular response to UV 2/83 90/18722 0.0605332453960753 0.272480778875387 PARP1/DHX36 2 GO:0042475 odontogenesis of dentin-containing tooth 2/83 90/18722 0.0605332453960753 0.272480778875387 CSF3R/HTRA1 2 GO:0099175 regulation of postsynapse organization 2/83 90/18722 0.0605332453960753 0.272480778875387 NRP2/DHX36 2 GO:0014033 neural crest cell differentiation 2/83 91/18722 0.0617202409781825 0.272480778875387 NRP2/SEMA6A 2 GO:0071383 cellular response to steroid hormone stimulus 3/83 204/18722 0.0621803767438369 0.272480778875387 SERPINF1/ATP2B1/PARP1 3 GO:0062197 cellular response to chemical stress 4/83 337/18722 0.0627654286704333 0.272480778875387 JUN/PAGE4/PARP1/MET 4 GO:0001655 urogenital system development 4/83 338/18722 0.0633112146792766 0.272480778875387 LGR5/SERPINF1/PBX1/FSTL3 4 GO:0060349 bone morphogenesis 2/83 93/18722 0.0641180528959427 0.272480778875387 PAPPA2/LRP5 2 GO:0106027 neuron projection organization 2/83 93/18722 0.0641180528959427 0.272480778875387 APP/DHX36 2 GO:1901992 positive regulation of mitotic cell cycle phase transition 2/83 93/18722 0.0641180528959427 0.272480778875387 APP/PBX1 2 GO:0050679 positive regulation of epithelial cell proliferation 3/83 207/18722 0.0643793432517079 0.272480778875387 IGF2/HTRA1/NRP2 3 GO:0000478 endonucleolytic cleavage involved in rRNA processing 1/83 15/18722 0.064498130790954 0.272480778875387 RPS21 1 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/83 15/18722 0.064498130790954 0.272480778875387 RPS21 1 GO:0002730 regulation of dendritic cell cytokine production 1/83 15/18722 0.064498130790954 0.272480778875387 DHX36 1 GO:0006089 lactate metabolic process 1/83 15/18722 0.064498130790954 0.272480778875387 LDHA 1 GO:0006704 glucocorticoid biosynthetic process 1/83 15/18722 0.064498130790954 0.272480778875387 CYP11A1 1 GO:0006878 cellular copper ion homeostasis 1/83 15/18722 0.064498130790954 0.272480778875387 APP 1 GO:0019511 peptidyl-proline hydroxylation 1/83 15/18722 0.064498130790954 0.272480778875387 EGLN3 1 GO:0042074 cell migration involved in gastrulation 1/83 15/18722 0.064498130790954 0.272480778875387 LRP5 1 GO:0045725 positive regulation of glycogen biosynthetic process 1/83 15/18722 0.064498130790954 0.272480778875387 IGF2 1 GO:0046459 short-chain fatty acid metabolic process 1/83 15/18722 0.064498130790954 0.272480778875387 ACSS1 1 GO:0048569 post-embryonic animal organ development 1/83 15/18722 0.064498130790954 0.272480778875387 LDHA 1 GO:0050746 regulation of lipoprotein metabolic process 1/83 15/18722 0.064498130790954 0.272480778875387 ITGAV 1 GO:0060253 negative regulation of glial cell proliferation 1/83 15/18722 0.064498130790954 0.272480778875387 ASCL2 1 GO:0097468 programmed cell death in response to reactive oxygen species 1/83 15/18722 0.064498130790954 0.272480778875387 MET 1 GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1/83 15/18722 0.064498130790954 0.272480778875387 DHX36 1 GO:1901660 calcium ion export 1/83 15/18722 0.064498130790954 0.272480778875387 ATP2B1 1 GO:1904424 regulation of GTP binding 1/83 15/18722 0.064498130790954 0.272480778875387 MET 1 GO:1905168 positive regulation of double-strand break repair via homologous recombination 1/83 15/18722 0.064498130790954 0.272480778875387 PARP1 1 GO:2001028 positive regulation of endothelial cell chemotaxis 1/83 15/18722 0.064498130790954 0.272480778875387 MET 1 GO:0010389 regulation of G2/M transition of mitotic cell cycle 2/83 94/18722 0.0653286858197931 0.272480778875387 APP/PBX1 2 GO:0051702 biological process involved in interaction with symbiont 2/83 94/18722 0.0653286858197931 0.272480778875387 JUN/GAPDH 2 GO:0061326 renal tubule development 2/83 94/18722 0.0653286858197931 0.272480778875387 LGR5/PBX1 2 GO:1902905 positive regulation of supramolecular fiber organization 3/83 209/18722 0.0658652165052387 0.272480778875387 IQGAP2/APP/MET 3 GO:0030336 negative regulation of cell migration 4/83 344/18722 0.066638769135804 0.272480778875387 TCAF1/SERPINF1/ADGRG1/ENG 4 GO:0030100 regulation of endocytosis 3/83 211/18722 0.0673668783071546 0.272480778875387 LRPAP1/ITGAV/AAK1 3 GO:0043491 protein kinase B signaling 3/83 211/18722 0.0673668783071546 0.272480778875387 IGF2/MET/ENG 3 GO:0050807 regulation of synapse organization 3/83 211/18722 0.0673668783071546 0.272480778875387 NRP2/APP/DHX36 3 GO:0010769 regulation of cell morphogenesis involved in differentiation 2/83 96/18722 0.067772951857116 0.272480778875387 PRKDC/DHX36 2 GO:0035282 segmentation 2/83 96/18722 0.067772951857116 0.272480778875387 NRP2/PRKDC 2 GO:0044264 cellular polysaccharide metabolic process 2/83 96/18722 0.067772951857116 0.272480778875387 IGF2/AGL 2 GO:1901655 cellular response to ketone 2/83 96/18722 0.067772951857116 0.272480778875387 SERPINF1/ATP2B1 2 GO:0009749 response to glucose 3/83 212/18722 0.0681235951067369 0.272480778875387 LDHA/SERPINF1/LRP5 3 GO:0043523 regulation of neuron apoptotic process 3/83 212/18722 0.0681235951067369 0.272480778875387 JUN/EGLN3/PARP1 3 GO:0070482 response to oxygen levels 4/83 347/18722 0.0683363691095485 0.272480778875387 LDHA/PDLIM1/ASCL2/EGLN3 4 GO:0002371 dendritic cell cytokine production 1/83 16/18722 0.0686488046106122 0.272480778875387 DHX36 1 GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation 1/83 16/18722 0.0686488046106122 0.272480778875387 ENG 1 GO:0005980 glycogen catabolic process 1/83 16/18722 0.0686488046106122 0.272480778875387 AGL 1 GO:0006349 regulation of gene expression by genetic imprinting 1/83 16/18722 0.0686488046106122 0.272480778875387 IGF2 1 GO:0009415 response to water 1/83 16/18722 0.0686488046106122 0.272480778875387 KRT8 1 GO:0017014 protein nitrosylation 1/83 16/18722 0.0686488046106122 0.272480778875387 GAPDH 1 GO:0018119 peptidyl-cysteine S-nitrosylation 1/83 16/18722 0.0686488046106122 0.272480778875387 GAPDH 1 GO:0021783 preganglionic parasympathetic fiber development 1/83 16/18722 0.0686488046106122 0.272480778875387 NRP2 1 GO:0030033 microvillus assembly 1/83 16/18722 0.0686488046106122 0.272480778875387 FXYD5 1 GO:0043923 positive regulation by host of viral transcription 1/83 16/18722 0.0686488046106122 0.272480778875387 JUN 1 GO:0050862 positive regulation of T cell receptor signaling pathway 1/83 16/18722 0.0686488046106122 0.272480778875387 KCNN4 1 GO:0061548 ganglion development 1/83 16/18722 0.0686488046106122 0.272480778875387 NRP2 1 GO:0097284 hepatocyte apoptotic process 1/83 16/18722 0.0686488046106122 0.272480778875387 KRT8 1 GO:0099010 modification of postsynaptic structure 1/83 16/18722 0.0686488046106122 0.272480778875387 MYH10 1 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration 1/83 16/18722 0.0686488046106122 0.272480778875387 ATP2B1 1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway 1/83 16/18722 0.0686488046106122 0.272480778875387 SEMA6A 1 GO:1905906 regulation of amyloid fibril formation 1/83 16/18722 0.0686488046106122 0.272480778875387 APP 1 GO:2000765 regulation of cytoplasmic translation 1/83 16/18722 0.0686488046106122 0.272480778875387 DHX36 1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining 1/83 16/18722 0.0686488046106122 0.272480778875387 PRKDC 1 GO:2001224 positive regulation of neuron migration 1/83 16/18722 0.0686488046106122 0.272480778875387 SEMA6A 1 GO:1901216 positive regulation of neuron death 2/83 97/18722 0.0690064053744044 0.273338896698204 JUN/PARP1 2 GO:0009612 response to mechanical stimulus 3/83 216/18722 0.0711893712856668 0.278077229137884 JUN/SERPINE2/ENG 3 GO:0060291 long-term synaptic potentiation 2/83 99/18722 0.0714955091210473 0.278077229137884 APP/SERPINE2 2 GO:0006066 alcohol metabolic process 4/83 353/18722 0.0717987475869673 0.278077229137884 CYP11A1/APP/LRP5/ACSS1 4 GO:0050803 regulation of synapse structure or activity 3/83 218/18722 0.0727454033940791 0.278077229137884 NRP2/APP/DHX36 3 GO:0006390 mitochondrial transcription 1/83 17/18722 0.0727812834525517 0.278077229137884 TFAM 1 GO:0009251 glucan catabolic process 1/83 17/18722 0.0727812834525517 0.278077229137884 AGL 1 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 1/83 17/18722 0.0727812834525517 0.278077229137884 HLA-C 1 GO:0030322 stabilization of membrane potential 1/83 17/18722 0.0727812834525517 0.278077229137884 KCNN4 1 GO:0033151 V(D)J recombination 1/83 17/18722 0.0727812834525517 0.278077229137884 PRKDC 1 GO:0043968 histone H2A acetylation 1/83 17/18722 0.0727812834525517 0.278077229137884 MORF4L2 1 GO:0048532 anatomical structure arrangement 1/83 17/18722 0.0727812834525517 0.278077229137884 NRP2 1 GO:0061158 3'-UTR-mediated mRNA destabilization 1/83 17/18722 0.0727812834525517 0.278077229137884 DHX36 1 GO:0061298 retina vasculature development in camera-type eye 1/83 17/18722 0.0727812834525517 0.278077229137884 LRP5 1 GO:0070875 positive regulation of glycogen metabolic process 1/83 17/18722 0.0727812834525517 0.278077229137884 IGF2 1 GO:1902358 sulfate transmembrane transport 1/83 17/18722 0.0727812834525517 0.278077229137884 SLC26A2 1 GO:0009746 response to hexose 3/83 219/18722 0.0735291544322352 0.278077229137884 LDHA/SERPINF1/LRP5 3 GO:0097191 extrinsic apoptotic signaling pathway 3/83 219/18722 0.0735291544322352 0.278077229137884 KRT8/TNFSF10/ITGAV 3 GO:0042102 positive regulation of T cell proliferation 2/83 101/18722 0.0740136233541018 0.278077229137884 IGF2/EBI3 2 GO:0010631 epithelial cell migration 4/83 357/18722 0.074156437802194 0.278077229137884 NRP2/S100P/SERPINF1/MET 4 GO:1904062 regulation of cation transmembrane transport 4/83 357/18722 0.074156437802194 0.278077229137884 UTRN/KCNN4/APP/FXYD5 4 GO:0048705 skeletal system morphogenesis 3/83 220/18722 0.0743167091063516 0.278077229137884 FBN2/PAPPA2/LRP5 3 GO:0008406 gonad development 3/83 221/18722 0.075108052537968 0.278077229137884 TNFSF10/FSTL3/ADGRG1 3 GO:0034308 primary alcohol metabolic process 2/83 102/18722 0.0752833422880287 0.278077229137884 CYP11A1/ACSS1 2 GO:1902749 regulation of cell cycle G2/M phase transition 2/83 102/18722 0.0752833422880287 0.278077229137884 APP/PBX1 2 GO:0009306 protein secretion 4/83 359/18722 0.075350019415193 0.278077229137884 WLS/MYH10/KCNN4/LRP5 4 GO:2000146 negative regulation of cell motility 4/83 359/18722 0.075350019415193 0.278077229137884 TCAF1/SERPINF1/ADGRG1/ENG 4 GO:0000302 response to reactive oxygen species 3/83 222/18722 0.0759031697598661 0.278077229137884 LDHA/JUN/MET 3 GO:0035592 establishment of protein localization to extracellular region 4/83 360/18722 0.075950479877087 0.278077229137884 WLS/MYH10/KCNN4/LRP5 4 GO:0090132 epithelium migration 4/83 360/18722 0.075950479877087 0.278077229137884 NRP2/S100P/SERPINF1/MET 4 GO:0003279 cardiac septum development 2/83 103/18722 0.076560054526673 0.278077229137884 NRP2/ENG 2 GO:0002076 osteoblast development 1/83 18/18722 0.0768956461081756 0.278077229137884 LRP5 1 GO:0006085 acetyl-CoA biosynthetic process 1/83 18/18722 0.0768956461081756 0.278077229137884 ACSS1 1 GO:0008272 sulfate transport 1/83 18/18722 0.0768956461081756 0.278077229137884 SLC26A2 1 GO:0010985 negative regulation of lipoprotein particle clearance 1/83 18/18722 0.0768956461081756 0.278077229137884 LRPAP1 1 GO:0019896 axonal transport of mitochondrion 1/83 18/18722 0.0768956461081756 0.278077229137884 ARMCX3 1 GO:0044247 cellular polysaccharide catabolic process 1/83 18/18722 0.0768956461081756 0.278077229137884 AGL 1 GO:0048486 parasympathetic nervous system development 1/83 18/18722 0.0768956461081756 0.278077229137884 NRP2 1 GO:0048643 positive regulation of skeletal muscle tissue development 1/83 18/18722 0.0768956461081756 0.278077229137884 IGF2 1 GO:0055070 copper ion homeostasis 1/83 18/18722 0.0768956461081756 0.278077229137884 APP 1 GO:0060391 positive regulation of SMAD protein signal transduction 1/83 18/18722 0.0768956461081756 0.278077229137884 PARP1 1 GO:0060973 cell migration involved in heart development 1/83 18/18722 0.0768956461081756 0.278077229137884 ENG 1 GO:0061484 hematopoietic stem cell homeostasis 1/83 18/18722 0.0768956461081756 0.278077229137884 ADGRG1 1 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1/83 18/18722 0.0768956461081756 0.278077229137884 DHX36 1 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus 1/83 18/18722 0.0768956461081756 0.278077229137884 SEMA6A 1 GO:0008037 cell recognition 3/83 225/18722 0.0783110131983089 0.278077229137884 ALDOA/APP/LY6K 3 GO:0010001 glial cell differentiation 3/83 225/18722 0.0783110131983089 0.278077229137884 SPINT1/APP/SERPINE2 3 GO:0034284 response to monosaccharide 3/83 225/18722 0.0783110131983089 0.278077229137884 LDHA/SERPINF1/LRP5 3 GO:0090130 tissue migration 4/83 365/18722 0.0789893068063583 0.278077229137884 NRP2/S100P/SERPINF1/MET 4 GO:2001022 positive regulation of response to DNA damage stimulus 2/83 105/18722 0.0791341188263203 0.278077229137884 PRKDC/PARP1 2 GO:0007411 axon guidance 3/83 227/18722 0.0799348328649485 0.278077229137884 NRP2/APP/SEMA6A 3 GO:0045137 development of primary sexual characteristics 3/83 227/18722 0.0799348328649485 0.278077229137884 TNFSF10/FSTL3/ADGRG1 3 GO:0046777 protein autophosphorylation 3/83 227/18722 0.0799348328649485 0.278077229137884 FLT1/AAK1/ENG 3 GO:0051271 negative regulation of cellular component movement 4/83 367/18722 0.0802217996665706 0.278077229137884 TCAF1/SERPINF1/ADGRG1/ENG 4 GO:0030038 contractile actin filament bundle assembly 2/83 106/18722 0.0804313023409695 0.278077229137884 PDLIM1/MET 2 GO:0043149 stress fiber assembly 2/83 106/18722 0.0804313023409695 0.278077229137884 PDLIM1/MET 2 GO:0090263 positive regulation of canonical Wnt signaling pathway 2/83 106/18722 0.0804313023409695 0.278077229137884 WLS/LGR5 2 GO:0097485 neuron projection guidance 3/83 228/18722 0.0807522737529628 0.278077229137884 NRP2/APP/SEMA6A 3 GO:0000028 ribosomal small subunit assembly 1/83 19/18722 0.0809919710318825 0.278077229137884 PRKDC 1 GO:0002483 antigen processing and presentation of endogenous peptide antigen 1/83 19/18722 0.0809919710318825 0.278077229137884 HLA-C 1 GO:0002888 positive regulation of myeloid leukocyte mediated immunity 1/83 19/18722 0.0809919710318825 0.278077229137884 DHX36 1 GO:0006007 glucose catabolic process 1/83 19/18722 0.0809919710318825 0.278077229137884 LRP5 1 GO:0010002 cardioblast differentiation 1/83 19/18722 0.0809919710318825 0.278077229137884 DHX36 1 GO:0010544 negative regulation of platelet activation 1/83 19/18722 0.0809919710318825 0.278077229137884 SERPINE2 1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling 1/83 19/18722 0.0809919710318825 0.278077229137884 SERPINE2 1 GO:0030011 maintenance of cell polarity 1/83 19/18722 0.0809919710318825 0.278077229137884 PDLIM1 1 GO:0030220 platelet formation 1/83 19/18722 0.0809919710318825 0.278077229137884 PRKDC 1 GO:0036344 platelet morphogenesis 1/83 19/18722 0.0809919710318825 0.278077229137884 PRKDC 1 GO:0044320 cellular response to leptin stimulus 1/83 19/18722 0.0809919710318825 0.278077229137884 EBI3 1 GO:0045603 positive regulation of endothelial cell differentiation 1/83 19/18722 0.0809919710318825 0.278077229137884 BTG1 1 GO:0045821 positive regulation of glycolytic process 1/83 19/18722 0.0809919710318825 0.278077229137884 APP 1 GO:0046716 muscle cell cellular homeostasis 1/83 19/18722 0.0809919710318825 0.278077229137884 ALDOA 1 GO:1900221 regulation of amyloid-beta clearance 1/83 19/18722 0.0809919710318825 0.278077229137884 LRPAP1 1 GO:2000269 regulation of fibroblast apoptotic process 1/83 19/18722 0.0809919710318825 0.278077229137884 BTG1 1 GO:2000369 regulation of clathrin-dependent endocytosis 1/83 19/18722 0.0809919710318825 0.278077229137884 AAK1 1 GO:2000738 positive regulation of stem cell differentiation 1/83 19/18722 0.0809919710318825 0.278077229137884 DHX36 1 GO:0001649 osteoblast differentiation 3/83 229/18722 0.0815733813125331 0.278158502822254 FBN2/IGF2/LRP5 3 GO:0005976 polysaccharide metabolic process 2/83 107/18722 0.0817351420605485 0.278158502822254 IGF2/AGL 2 GO:0007229 integrin-mediated signaling pathway 2/83 107/18722 0.0817351420605485 0.278158502822254 ITGAV/ISG15 2 GO:0008637 apoptotic mitochondrial changes 2/83 107/18722 0.0817351420605485 0.278158502822254 JUN/TNFSF10 2 GO:0010927 cellular component assembly involved in morphogenesis 2/83 107/18722 0.0817351420605485 0.278158502822254 KRT19/KRT8 2 GO:0002832 negative regulation of response to biotic stimulus 2/83 108/18722 0.083045555195526 0.279691355066684 HTRA1/ISG15 2 GO:0010594 regulation of endothelial cell migration 3/83 232/18722 0.0840585474601297 0.279691355066684 NRP2/SERPINF1/MET 3 GO:0006821 chloride transport 2/83 109/18722 0.0843624595435237 0.279691355066684 SLC26A2/CLIC3 2 GO:0000272 polysaccharide catabolic process 1/83 20/18722 0.0850703363424933 0.279691355066684 AGL 1 GO:0006700 C21-steroid hormone biosynthetic process 1/83 20/18722 0.0850703363424933 0.279691355066684 CYP11A1 1 GO:0007620 copulation 1/83 20/18722 0.0850703363424933 0.279691355066684 SERPINE2 1 GO:0010042 response to manganese ion 1/83 20/18722 0.0850703363424933 0.279691355066684 APP 1 GO:0042359 vitamin D metabolic process 1/83 20/18722 0.0850703363424933 0.279691355066684 CYP11A1 1 GO:0045844 positive regulation of striated muscle tissue development 1/83 20/18722 0.0850703363424933 0.279691355066684 IGF2 1 GO:0048636 positive regulation of muscle organ development 1/83 20/18722 0.0850703363424933 0.279691355066684 IGF2 1 GO:0051900 regulation of mitochondrial depolarization 1/83 20/18722 0.0850703363424933 0.279691355066684 PARP1 1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway 1/83 20/18722 0.0850703363424933 0.279691355066684 ISG15 1 GO:0061003 positive regulation of dendritic spine morphogenesis 1/83 20/18722 0.0850703363424933 0.279691355066684 DHX36 1 GO:0071243 cellular response to arsenic-containing substance 1/83 20/18722 0.0850703363424933 0.279691355066684 DHX36 1 GO:1903206 negative regulation of hydrogen peroxide-induced cell death 1/83 20/18722 0.0850703363424933 0.279691355066684 MET 1 GO:0018108 peptidyl-tyrosine phosphorylation 4/83 375/18722 0.0852477691626186 0.279691355066684 IGF2/FLT1/APP/MET 4 GO:0007088 regulation of mitotic nuclear division 2/83 110/18722 0.0856857734858415 0.279691355066684 IGF2/LRP5 2 GO:0048588 developmental cell growth 3/83 234/18722 0.0857333699466236 0.279691355066684 NRP2/APP/SEMA6A 3 GO:0060560 developmental growth involved in morphogenesis 3/83 234/18722 0.0857333699466236 0.279691355066684 NRP2/APP/SEMA6A 3 GO:0001938 positive regulation of endothelial cell proliferation 2/83 111/18722 0.087015415984003 0.279691355066684 IGF2/NRP2 2 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 2/83 111/18722 0.087015415984003 0.279691355066684 FLT1/SERPINE2 2 GO:0018212 peptidyl-tyrosine modification 4/83 378/18722 0.0871717587848919 0.279691355066684 IGF2/FLT1/APP/MET 4 GO:0048762 mesenchymal cell differentiation 3/83 236/18722 0.0874224798532538 0.279691355066684 NRP2/ENG/SEMA6A 3 GO:0050878 regulation of body fluid levels 4/83 379/18722 0.0878178060314121 0.279691355066684 F5/KCNN4/SERPINE2/MET 4 GO:0031334 positive regulation of protein-containing complex assembly 3/83 237/18722 0.0882723524415979 0.279691355066684 IQGAP2/ISG15/MET 3 GO:0032609 interferon-gamma production 2/83 112/18722 0.088351306576318 0.279691355066684 EBI3/ISG15 2 GO:0032649 regulation of interferon-gamma production 2/83 112/18722 0.088351306576318 0.279691355066684 EBI3/ISG15 2 GO:0048640 negative regulation of developmental growth 2/83 112/18722 0.088351306576318 0.279691355066684 PLAC8/SEMA6A 2 GO:0000002 mitochondrial genome maintenance 1/83 21/18722 0.089130819824665 0.279691355066684 PARP1 1 GO:0006067 ethanol metabolic process 1/83 21/18722 0.089130819824665 0.279691355066684 ACSS1 1 GO:0007350 blastoderm segmentation 1/83 21/18722 0.089130819824665 0.279691355066684 NRP2 1 GO:0007617 mating behavior 1/83 21/18722 0.089130819824665 0.279691355066684 APP 1 GO:0010766 negative regulation of sodium ion transport 1/83 21/18722 0.089130819824665 0.279691355066684 SERPINE2 1 GO:0023019 signal transduction involved in regulation of gene expression 1/83 21/18722 0.089130819824665 0.279691355066684 PARP1 1 GO:0034035 purine ribonucleoside bisphosphate metabolic process 1/83 21/18722 0.089130819824665 0.279691355066684 SLC26A2 1 GO:0045056 transcytosis 1/83 21/18722 0.089130819824665 0.279691355066684 LRPAP1 1 GO:0045655 regulation of monocyte differentiation 1/83 21/18722 0.089130819824665 0.279691355066684 JUN 1 GO:0046641 positive regulation of alpha-beta T cell proliferation 1/83 21/18722 0.089130819824665 0.279691355066684 EBI3 1 GO:0048485 sympathetic nervous system development 1/83 21/18722 0.089130819824665 0.279691355066684 NRP2 1 GO:0048745 smooth muscle tissue development 1/83 21/18722 0.089130819824665 0.279691355066684 ENG 1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process 1/83 21/18722 0.089130819824665 0.279691355066684 SLC26A2 1 GO:0051152 positive regulation of smooth muscle cell differentiation 1/83 21/18722 0.089130819824665 0.279691355066684 ENG 1 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 1/83 21/18722 0.089130819824665 0.279691355066684 DHX36 1 GO:1901863 positive regulation of muscle tissue development 1/83 21/18722 0.089130819824665 0.279691355066684 IGF2 1 GO:1902644 tertiary alcohol metabolic process 1/83 21/18722 0.089130819824665 0.279691355066684 CYP11A1 1 GO:1903427 negative regulation of reactive oxygen species biosynthetic process 1/83 21/18722 0.089130819824665 0.279691355066684 PAGE4 1 GO:1905209 positive regulation of cardiocyte differentiation 1/83 21/18722 0.089130819824665 0.279691355066684 DHX36 1 GO:2000178 negative regulation of neural precursor cell proliferation 1/83 21/18722 0.089130819824665 0.279691355066684 SPINT1 1 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2/83 114/18722 0.0910415130600918 0.28185347954973 PARP1/ENG 2 GO:0046916 cellular transition metal ion homeostasis 2/83 115/18722 0.0923956708814315 0.28185347954973 APP/SLC40A1 2 GO:1901989 positive regulation of cell cycle phase transition 2/83 115/18722 0.0923956708814315 0.28185347954973 APP/PBX1 2 GO:0002053 positive regulation of mesenchymal cell proliferation 1/83 22/18722 0.093173498930304 0.28185347954973 LRP5 1 GO:0002320 lymphoid progenitor cell differentiation 1/83 22/18722 0.093173498930304 0.28185347954973 PRKDC 1 GO:0006359 regulation of transcription by RNA polymerase III 1/83 22/18722 0.093173498930304 0.28185347954973 DHX36 1 GO:0008211 glucocorticoid metabolic process 1/83 22/18722 0.093173498930304 0.28185347954973 CYP11A1 1 GO:0021854 hypothalamus development 1/83 22/18722 0.093173498930304 0.28185347954973 NRP2 1 GO:0032727 positive regulation of interferon-alpha production 1/83 22/18722 0.093173498930304 0.28185347954973 DHX36 1 GO:0034755 iron ion transmembrane transport 1/83 22/18722 0.093173498930304 0.28185347954973 SLC40A1 1 GO:0035024 negative regulation of Rho protein signal transduction 1/83 22/18722 0.093173498930304 0.28185347954973 MET 1 GO:0044346 fibroblast apoptotic process 1/83 22/18722 0.093173498930304 0.28185347954973 BTG1 1 GO:0045663 positive regulation of myoblast differentiation 1/83 22/18722 0.093173498930304 0.28185347954973 BTG1 1 GO:0046628 positive regulation of insulin receptor signaling pathway 1/83 22/18722 0.093173498930304 0.28185347954973 IGF2 1 GO:0048169 regulation of long-term neuronal synaptic plasticity 1/83 22/18722 0.093173498930304 0.28185347954973 APP 1 GO:0051412 response to corticosterone 1/83 22/18722 0.093173498930304 0.28185347954973 ATP2B1 1 GO:0060343 trabecula formation 1/83 22/18722 0.093173498930304 0.28185347954973 FBN2 1 GO:0060444 branching involved in mammary gland duct morphogenesis 1/83 22/18722 0.093173498930304 0.28185347954973 LRP5 1 GO:0060713 labyrinthine layer morphogenesis 1/83 22/18722 0.093173498930304 0.28185347954973 SPINT1 1 GO:0099563 modification of synaptic structure 1/83 22/18722 0.093173498930304 0.28185347954973 MYH10 1 GO:1900543 negative regulation of purine nucleotide metabolic process 1/83 22/18722 0.093173498930304 0.28185347954973 PARP1 1 GO:1901032 negative regulation of response to reactive oxygen species 1/83 22/18722 0.093173498930304 0.28185347954973 MET 1 GO:2000773 negative regulation of cellular senescence 1/83 22/18722 0.093173498930304 0.28185347954973 PRKDC 1 GO:0018107 peptidyl-threonine phosphorylation 2/83 116/18722 0.0937557606499427 0.28317169583803 PRKDC/APP 2 GO:0006898 receptor-mediated endocytosis 3/83 244/18722 0.094319206545345 0.284429058115682 LRPAP1/ITGAV/AAK1 3 GO:0006814 sodium ion transport 3/83 245/18722 0.0951968096102765 0.286409459386716 UTRN/SERPINE2/FXYD5 3 GO:0045446 endothelial cell differentiation 2/83 118/18722 0.0964934260703763 0.286409459386716 BTG1/MET 2 GO:0051101 regulation of DNA binding 2/83 118/18722 0.0964934260703763 0.286409459386716 JUN/PARP1 2 GO:0010888 negative regulation of lipid storage 1/83 23/18722 0.097198450779972 0.286409459386716 ITGAV 1 GO:0021871 forebrain regionalization 1/83 23/18722 0.097198450779972 0.286409459386716 ADGRG1 1 GO:0021884 forebrain neuron development 1/83 23/18722 0.097198450779972 0.286409459386716 NRP2 1 GO:0035162 embryonic hemopoiesis 1/83 23/18722 0.097198450779972 0.286409459386716 PBX1 1 GO:0036303 lymph vessel morphogenesis 1/83 23/18722 0.097198450779972 0.286409459386716 SVEP1 1 GO:0045980 negative regulation of nucleotide metabolic process 1/83 23/18722 0.097198450779972 0.286409459386716 PARP1 1 GO:0051882 mitochondrial depolarization 1/83 23/18722 0.097198450779972 0.286409459386716 PARP1 1 GO:0060384 innervation 1/83 23/18722 0.097198450779972 0.286409459386716 SERPINE2 1 GO:0071305 cellular response to vitamin D 1/83 23/18722 0.097198450779972 0.286409459386716 ATP2B1 1 GO:0071514 genetic imprinting 1/83 23/18722 0.097198450779972 0.286409459386716 IGF2 1 GO:1900273 positive regulation of long-term synaptic potentiation 1/83 23/18722 0.097198450779972 0.286409459386716 APP 1 GO:2001169 regulation of ATP biosynthetic process 1/83 23/18722 0.097198450779972 0.286409459386716 PARP1 1 GO:0002761 regulation of myeloid leukocyte differentiation 2/83 120/18722 0.0992538949508637 0.28811593362822 JUN/FSTL3 2 GO:0030218 erythrocyte differentiation 2/83 120/18722 0.0992538949508637 0.28811593362822 PRKDC/ISG15 2 GO:0048593 camera-type eye morphogenesis 2/83 120/18722 0.0992538949508637 0.28811593362822 TENM3/LRP5 2 GO:0048675 axon extension 2/83 120/18722 0.0992538949508637 0.28811593362822 NRP2/SEMA6A 2 GO:0001704 formation of primary germ layer 2/83 121/18722 0.100642491106775 0.28811593362822 WLS/ITGAV 2 GO:0003206 cardiac chamber morphogenesis 2/83 121/18722 0.100642491106775 0.28811593362822 NRP2/ENG 2 GO:0045931 positive regulation of mitotic cell cycle 2/83 121/18722 0.100642491106775 0.28811593362822 APP/PBX1 2 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/83 24/18722 0.101205752164284 0.28811593362822 RPS21 1 GO:0001702 gastrulation with mouth forming second 1/83 24/18722 0.101205752164284 0.28811593362822 LRP5 1 GO:0001779 natural killer cell differentiation 1/83 24/18722 0.101205752164284 0.28811593362822 PBX1 1 GO:0010288 response to lead ion 1/83 24/18722 0.101205752164284 0.28811593362822 APP 1 GO:0021801 cerebral cortex radial glia-guided migration 1/83 24/18722 0.101205752164284 0.28811593362822 ADGRG1 1 GO:0022030 telencephalon glial cell migration 1/83 24/18722 0.101205752164284 0.28811593362822 ADGRG1 1 GO:0031639 plasminogen activation 1/83 24/18722 0.101205752164284 0.28811593362822 SERPINE2 1 GO:0032528 microvillus organization 1/83 24/18722 0.101205752164284 0.28811593362822 FXYD5 1 GO:0044321 response to leptin 1/83 24/18722 0.101205752164284 0.28811593362822 EBI3 1 GO:0048641 regulation of skeletal muscle tissue development 1/83 24/18722 0.101205752164284 0.28811593362822 IGF2 1 GO:0050687 negative regulation of defense response to virus 1/83 24/18722 0.101205752164284 0.28811593362822 HTRA1 1 GO:0060561 apoptotic process involved in morphogenesis 1/83 24/18722 0.101205752164284 0.28811593362822 LRP5 1 GO:0071294 cellular response to zinc ion 1/83 24/18722 0.101205752164284 0.28811593362822 PARP1 1 GO:2000310 regulation of NMDA receptor activity 1/83 24/18722 0.101205752164284 0.28811593362822 APP 1 GO:2000679 positive regulation of transcription regulatory region DNA binding 1/83 24/18722 0.101205752164284 0.28811593362822 PARP1 1 GO:2001026 regulation of endothelial cell chemotaxis 1/83 24/18722 0.101205752164284 0.28811593362822 MET 1 GO:0009743 response to carbohydrate 3/83 253/18722 0.102338339483958 0.290911779738956 LDHA/SERPINF1/LRP5 3 GO:0071482 cellular response to light stimulus 2/83 123/18722 0.10343603245259 0.292579657497955 PARP1/DHX36 2 GO:0007611 learning or memory 3/83 255/18722 0.104156632816449 0.292579657497955 JUN/APP/SERPINF1 3 GO:0090596 sensory organ morphogenesis 3/83 256/18722 0.105070622617669 0.292579657497955 FBN2/TENM3/LRP5 3 GO:0010447 response to acidic pH 1/83 25/18722 0.105195479545307 0.292579657497955 SERPINF1 1 GO:0016540 protein autoprocessing 1/83 25/18722 0.105195479545307 0.292579657497955 PARP1 1 GO:0032469 endoplasmic reticulum calcium ion homeostasis 1/83 25/18722 0.105195479545307 0.292579657497955 APP 1 GO:0032925 regulation of activin receptor signaling pathway 1/83 25/18722 0.105195479545307 0.292579657497955 FSTL3 1 GO:0048143 astrocyte activation 1/83 25/18722 0.105195479545307 0.292579657497955 APP 1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 1/83 25/18722 0.105195479545307 0.292579657497955 DHX36 1 GO:0061436 establishment of skin barrier 1/83 25/18722 0.105195479545307 0.292579657497955 MET 1 GO:0090330 regulation of platelet aggregation 1/83 25/18722 0.105195479545307 0.292579657497955 SERPINE2 1 GO:1900078 positive regulation of cellular response to insulin stimulus 1/83 25/18722 0.105195479545307 0.292579657497955 IGF2 1 GO:1903959 regulation of anion transmembrane transport 1/83 25/18722 0.105195479545307 0.292579657497955 TCAF1 1 GO:1905563 negative regulation of vascular endothelial cell proliferation 1/83 25/18722 0.105195479545307 0.292579657497955 FLT1 1 GO:1905564 positive regulation of vascular endothelial cell proliferation 1/83 25/18722 0.105195479545307 0.292579657497955 IGF2 1 GO:0018210 peptidyl-threonine modification 2/83 125/18722 0.106250879601079 0.295090445788628 PRKDC/APP 2 GO:0031348 negative regulation of defense response 3/83 258/18722 0.106908202827665 0.29649003739724 HTRA1/SERPINF1/ISG15 3 GO:0035270 endocrine system development 2/83 127/18722 0.109086448524826 0.298474089970301 PBX1/FSTL3 2 GO:0014829 vascular associated smooth muscle contraction 1/83 26/18722 0.109167709057942 0.298474089970301 ATP2B1 1 GO:0019883 antigen processing and presentation of endogenous antigen 1/83 26/18722 0.109167709057942 0.298474089970301 HLA-C 1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated 1/83 26/18722 0.109167709057942 0.298474089970301 ARMCX3 1 GO:0047497 mitochondrion transport along microtubule 1/83 26/18722 0.109167709057942 0.298474089970301 ARMCX3 1 GO:0048668 collateral sprouting 1/83 26/18722 0.109167709057942 0.298474089970301 APP 1 GO:0048843 negative regulation of axon extension involved in axon guidance 1/83 26/18722 0.109167709057942 0.298474089970301 SEMA6A 1 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 1/83 26/18722 0.109167709057942 0.298474089970301 KCNN4 1 GO:0097186 amelogenesis 1/83 26/18722 0.109167709057942 0.298474089970301 CSF3R 1 GO:1905063 regulation of vascular associated smooth muscle cell differentiation 1/83 26/18722 0.109167709057942 0.298474089970301 ENG 1 GO:0033865 nucleoside bisphosphate metabolic process 2/83 128/18722 0.110511823454039 0.299968624230712 SLC26A2/ACSS1 2 GO:0033875 ribonucleoside bisphosphate metabolic process 2/83 128/18722 0.110511823454039 0.299968624230712 SLC26A2/ACSS1 2 GO:0034032 purine nucleoside bisphosphate metabolic process 2/83 128/18722 0.110511823454039 0.299968624230712 SLC26A2/ACSS1 2 GO:0001558 regulation of cell growth 4/83 414/18722 0.111869755540019 0.299968624230712 BTG1/PAPPA2/SERPINE2/SEMA6A 4 GO:0034101 erythrocyte homeostasis 2/83 129/18722 0.111942163635004 0.299968624230712 PRKDC/ISG15 2 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 2/83 129/18722 0.111942163635004 0.299968624230712 TNFSF10/EGLN3 2 GO:0000469 cleavage involved in rRNA processing 1/83 27/18722 0.113122516511311 0.299968624230712 RPS21 1 GO:0003272 endocardial cushion formation 1/83 27/18722 0.113122516511311 0.299968624230712 ENG 1 GO:0009651 response to salt stress 1/83 27/18722 0.113122516511311 0.299968624230712 PAPPA2 1 GO:0018126 protein hydroxylation 1/83 27/18722 0.113122516511311 0.299968624230712 EGLN3 1 GO:0032967 positive regulation of collagen biosynthetic process 1/83 27/18722 0.113122516511311 0.299968624230712 ENG 1 GO:0033561 regulation of water loss via skin 1/83 27/18722 0.113122516511311 0.299968624230712 MET 1 GO:0035235 ionotropic glutamate receptor signaling pathway 1/83 27/18722 0.113122516511311 0.299968624230712 APP 1 GO:0042104 positive regulation of activated T cell proliferation 1/83 27/18722 0.113122516511311 0.299968624230712 IGF2 1 GO:1900746 regulation of vascular endothelial growth factor signaling pathway 1/83 27/18722 0.113122516511311 0.299968624230712 SEMA6A 1 GO:1902883 negative regulation of response to oxidative stress 1/83 27/18722 0.113122516511311 0.299968624230712 MET 1 GO:1903203 regulation of oxidative stress-induced neuron death 1/83 27/18722 0.113122516511311 0.299968624230712 PARP1 1 GO:1903205 regulation of hydrogen peroxide-induced cell death 1/83 27/18722 0.113122516511311 0.299968624230712 MET 1 GO:1904357 negative regulation of telomere maintenance via telomere lengthening 1/83 27/18722 0.113122516511311 0.299968624230712 PARP1 1 GO:0006282 regulation of DNA repair 2/83 130/18722 0.113377398421143 0.299968624230712 PRKDC/PARP1 2 GO:0042476 odontogenesis 2/83 130/18722 0.113377398421143 0.299968624230712 CSF3R/HTRA1 2 GO:0043467 regulation of generation of precursor metabolites and energy 2/83 130/18722 0.113377398421143 0.299968624230712 IGF2/APP 2 GO:0051607 defense response to virus 3/83 265/18722 0.113438729597853 0.299968624230712 HTRA1/ISG15/DHX36 3 GO:0140546 defense response to symbiont 3/83 265/18722 0.113438729597853 0.299968624230712 HTRA1/ISG15/DHX36 3 GO:0019827 stem cell population maintenance 2/83 131/18722 0.114817457680778 0.302509273121826 ASCL2/LRP5 2 GO:0045667 regulation of osteoblast differentiation 2/83 132/18722 0.116262271794039 0.302509273121826 FBN2/LRP5 2 GO:0001945 lymph vessel development 1/83 28/18722 0.117059977390133 0.302509273121826 SVEP1 1 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1/83 28/18722 0.117059977390133 0.302509273121826 HLA-C 1 GO:0010464 regulation of mesenchymal cell proliferation 1/83 28/18722 0.117059977390133 0.302509273121826 LRP5 1 GO:0010714 positive regulation of collagen metabolic process 1/83 28/18722 0.117059977390133 0.302509273121826 ENG 1 GO:0019098 reproductive behavior 1/83 28/18722 0.117059977390133 0.302509273121826 APP 1 GO:0031440 regulation of mRNA 3'-end processing 1/83 28/18722 0.117059977390133 0.302509273121826 DHX36 1 GO:0032607 interferon-alpha production 1/83 28/18722 0.117059977390133 0.302509273121826 DHX36 1 GO:0032647 regulation of interferon-alpha production 1/83 28/18722 0.117059977390133 0.302509273121826 DHX36 1 GO:0045671 negative regulation of osteoclast differentiation 1/83 28/18722 0.117059977390133 0.302509273121826 FSTL3 1 GO:0061082 myeloid leukocyte cytokine production 1/83 28/18722 0.117059977390133 0.302509273121826 DHX36 1 GO:0071280 cellular response to copper ion 1/83 28/18722 0.117059977390133 0.302509273121826 APP 1 GO:0090200 positive regulation of release of cytochrome c from mitochondria 1/83 28/18722 0.117059977390133 0.302509273121826 TNFSF10 1 GO:0090344 negative regulation of cell aging 1/83 28/18722 0.117059977390133 0.302509273121826 PRKDC 1 GO:1903671 negative regulation of sprouting angiogenesis 1/83 28/18722 0.117059977390133 0.302509273121826 SEMA6A 1 GO:1903779 regulation of cardiac conduction 1/83 28/18722 0.117059977390133 0.302509273121826 ATP2B1 1 GO:0010595 positive regulation of endothelial cell migration 2/83 133/18722 0.117711771649806 0.303787522829205 NRP2/MET 2 GO:0098727 maintenance of cell number 2/83 134/18722 0.119165888642652 0.304102291980264 ASCL2/LRP5 2 GO:0048872 homeostasis of number of cells 3/83 272/18722 0.120118708950652 0.304102291980264 PRKDC/ISG15/ADGRG1 3 GO:0050808 synapse organization 4/83 426/18722 0.120733307930707 0.304102291980264 NRP2/MYH10/APP/DHX36 4 GO:0002360 T cell lineage commitment 1/83 29/18722 0.120980166856091 0.304102291980264 PRKDC 1 GO:0003209 cardiac atrium morphogenesis 1/83 29/18722 0.120980166856091 0.304102291980264 ENG 1 GO:0005979 regulation of glycogen biosynthetic process 1/83 29/18722 0.120980166856091 0.304102291980264 IGF2 1 GO:0010955 negative regulation of protein processing 1/83 29/18722 0.120980166856091 0.304102291980264 SERPINE2 1 GO:0010962 regulation of glucan biosynthetic process 1/83 29/18722 0.120980166856091 0.304102291980264 IGF2 1 GO:0015701 bicarbonate transport 1/83 29/18722 0.120980166856091 0.304102291980264 SLC26A2 1 GO:0021602 cranial nerve morphogenesis 1/83 29/18722 0.120980166856091 0.304102291980264 NRP2 1 GO:0040018 positive regulation of multicellular organism growth 1/83 29/18722 0.120980166856091 0.304102291980264 IGF2 1 GO:0051654 establishment of mitochondrion localization 1/83 29/18722 0.120980166856091 0.304102291980264 ARMCX3 1 GO:0051873 killing by host of symbiont cells 1/83 29/18722 0.120980166856091 0.304102291980264 GAPDH 1 GO:0051883 killing of cells in other organism involved in symbiotic interaction 1/83 29/18722 0.120980166856091 0.304102291980264 GAPDH 1 GO:0071549 cellular response to dexamethasone stimulus 1/83 29/18722 0.120980166856091 0.304102291980264 SERPINF1 1 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 1/83 29/18722 0.120980166856091 0.304102291980264 PARP1 1 GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus 1/83 29/18722 0.120980166856091 0.304102291980264 SEMA6A 1 GO:1903318 negative regulation of protein maturation 1/83 29/18722 0.120980166856091 0.304102291980264 SERPINE2 1 GO:2000406 positive regulation of T cell migration 1/83 29/18722 0.120980166856091 0.304102291980264 APP 1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining 1/83 29/18722 0.120980166856091 0.304102291980264 PRKDC 1 GO:0043254 regulation of protein-containing complex assembly 4/83 427/18722 0.121485480527901 0.304975888130431 IQGAP2/ISG15/PARP1/MET 4 GO:0003158 endothelium development 2/83 136/18722 0.122087702128155 0.305148391659161 BTG1/MET 2 GO:0045727 positive regulation of translation 2/83 136/18722 0.122087702128155 0.305148391659161 PRKDC/DHX36 2 GO:0043270 positive regulation of ion transport 3/83 275/18722 0.123025819838787 0.305148391659161 TCAF1/KCNN4/ATP2B1 3 GO:0000086 G2/M transition of mitotic cell cycle 2/83 137/18722 0.123555263911206 0.305148391659161 APP/PBX1 2 GO:0007266 Rho protein signal transduction 2/83 137/18722 0.123555263911206 0.305148391659161 MET/ADGRG1 2 GO:0050671 positive regulation of lymphocyte proliferation 2/83 137/18722 0.123555263911206 0.305148391659161 IGF2/EBI3 2 GO:0055123 digestive system development 2/83 137/18722 0.123555263911206 0.305148391659161 IGF2/WLS 2 GO:0006884 cell volume homeostasis 1/83 30/18722 0.124883159749203 0.305148391659161 KCNN4 1 GO:0007176 regulation of epidermal growth factor-activated receptor activity 1/83 30/18722 0.124883159749203 0.305148391659161 APP 1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation 1/83 30/18722 0.124883159749203 0.305148391659161 APP 1 GO:0019674 NAD metabolic process 1/83 30/18722 0.124883159749203 0.305148391659161 LDHA 1 GO:0031571 mitotic G1 DNA damage checkpoint signaling 1/83 30/18722 0.124883159749203 0.305148391659161 PRKDC 1 GO:0044030 regulation of DNA methylation 1/83 30/18722 0.124883159749203 0.305148391659161 PARP1 1 GO:0060218 hematopoietic stem cell differentiation 1/83 30/18722 0.124883159749203 0.305148391659161 PRKDC 1 GO:0060603 mammary gland duct morphogenesis 1/83 30/18722 0.124883159749203 0.305148391659161 LRP5 1 GO:0060674 placenta blood vessel development 1/83 30/18722 0.124883159749203 0.305148391659161 SPINT1 1 GO:0061384 heart trabecula morphogenesis 1/83 30/18722 0.124883159749203 0.305148391659161 ENG 1 GO:0090314 positive regulation of protein targeting to membrane 1/83 30/18722 0.124883159749203 0.305148391659161 TCAF1 1 GO:1903579 negative regulation of ATP metabolic process 1/83 30/18722 0.124883159749203 0.305148391659161 PARP1 1 GO:0032273 positive regulation of protein polymerization 2/83 138/18722 0.125027173406133 0.305148391659161 IQGAP2/MET 2 GO:0032946 positive regulation of mononuclear cell proliferation 2/83 138/18722 0.125027173406133 0.305148391659161 IGF2/EBI3 2 GO:0055076 transition metal ion homeostasis 2/83 138/18722 0.125027173406133 0.305148391659161 APP/SLC40A1 2 GO:0045598 regulation of fat cell differentiation 2/83 139/18722 0.126503364490796 0.307878460485599 ADIRF/LRP5 2 GO:0051783 regulation of nuclear division 2/83 139/18722 0.126503364490796 0.307878460485599 IGF2/LRP5 2 GO:0002683 negative regulation of immune system process 4/83 434/18722 0.126807718373373 0.307878460485599 HTRA1/PRKDC/ISG15/FSTL3 4 GO:0042391 regulation of membrane potential 4/83 434/18722 0.126807718373373 0.307878460485599 JUN/KCNN4/APP/PARP1 4 GO:1902105 regulation of leukocyte differentiation 3/83 279/18722 0.126942127784285 0.307878460485599 JUN/PRKDC/FSTL3 3 GO:0030177 positive regulation of Wnt signaling pathway 2/83 140/18722 0.127983771530787 0.308439326058093 WLS/LGR5 2 GO:0050768 negative regulation of neurogenesis 2/83 140/18722 0.127983771530787 0.308439326058093 ASCL2/SEMA6A 2 GO:0007190 activation of adenylate cyclase activity 1/83 31/18722 0.128769030589178 0.308439326058093 LGR5 1 GO:0018200 peptidyl-glutamic acid modification 1/83 31/18722 0.128769030589178 0.308439326058093 PARP1 1 GO:0036474 cell death in response to hydrogen peroxide 1/83 31/18722 0.128769030589178 0.308439326058093 MET 1 GO:0036475 neuron death in response to oxidative stress 1/83 31/18722 0.128769030589178 0.308439326058093 PARP1 1 GO:0044819 mitotic G1/S transition checkpoint signaling 1/83 31/18722 0.128769030589178 0.308439326058093 PRKDC 1 GO:0048710 regulation of astrocyte differentiation 1/83 31/18722 0.128769030589178 0.308439326058093 SERPINE2 1 GO:0060390 regulation of SMAD protein signal transduction 1/83 31/18722 0.128769030589178 0.308439326058093 PARP1 1 GO:0070528 protein kinase C signaling 1/83 31/18722 0.128769030589178 0.308439326058093 ADGRG1 1 GO:1903532 positive regulation of secretion by cell 3/83 282/18722 0.129908859196283 0.310784436666355 WLS/MYH10/KCNN4 3 GO:0022409 positive regulation of cell-cell adhesion 3/83 284/18722 0.131900461782948 0.312288636984042 IGF2/EBI3/FSTL3 3 GO:0007015 actin filament organization 4/83 441/18722 0.132227990110567 0.312288636984042 ALDOA/PDLIM1/IQGAP2/MET 4 GO:0045936 negative regulation of phosphate metabolic process 4/83 441/18722 0.132227990110567 0.312288636984042 PRKDC/LRP5/PARP1/ENG 4 GO:0062013 positive regulation of small molecule metabolic process 2/83 143/18722 0.132449639293086 0.312288636984042 IGF2/APP 2 GO:0009954 proximal/distal pattern formation 1/83 32/18722 0.132637853576771 0.312288636984042 PBX1 1 GO:0010743 regulation of macrophage derived foam cell differentiation 1/83 32/18722 0.132637853576771 0.312288636984042 ITGAV 1 GO:0021799 cerebral cortex radially oriented cell migration 1/83 32/18722 0.132637853576771 0.312288636984042 ADGRG1 1 GO:0035767 endothelial cell chemotaxis 1/83 32/18722 0.132637853576771 0.312288636984042 MET 1 GO:0045879 negative regulation of smoothened signaling pathway 1/83 32/18722 0.132637853576771 0.312288636984042 SERPINE2 1 GO:0048841 regulation of axon extension involved in axon guidance 1/83 32/18722 0.132637853576771 0.312288636984042 SEMA6A 1 GO:0050685 positive regulation of mRNA processing 1/83 32/18722 0.132637853576771 0.312288636984042 DHX36 1 GO:0051497 negative regulation of stress fiber assembly 1/83 32/18722 0.132637853576771 0.312288636984042 MET 1 GO:0060317 cardiac epithelial to mesenchymal transition 1/83 32/18722 0.132637853576771 0.312288636984042 ENG 1 GO:0010563 negative regulation of phosphorus metabolic process 4/83 442/18722 0.133010170906749 0.312784258348839 PRKDC/LRP5/PARP1/ENG 4 GO:0007612 learning 2/83 144/18722 0.133946263462522 0.313342749544401 JUN/APP 2 GO:0014065 phosphatidylinositol 3-kinase signaling 2/83 144/18722 0.133946263462522 0.313342749544401 FLT1/SERPINE2 2 GO:0016055 Wnt signaling pathway 4/83 444/18722 0.134580350338524 0.313342749544401 WLS/APP/LGR5/LRP5 4 GO:0010975 regulation of neuron projection development 4/83 445/18722 0.135368333966157 0.313342749544401 TENM3/SERPINF1/DHX36/SEMA6A 4 GO:0051961 negative regulation of nervous system development 2/83 145/18722 0.135446782629013 0.313342749544401 ASCL2/SEMA6A 2 GO:0061351 neural precursor cell proliferation 2/83 145/18722 0.135446782629013 0.313342749544401 SPINT1/ADGRG1 2 GO:0198738 cell-cell signaling by wnt 4/83 446/18722 0.13615823682292 0.313342749544401 WLS/APP/LGR5/LRP5 4 GO:0003382 epithelial cell morphogenesis 1/83 33/18722 0.13648970259513 0.313342749544401 MET 1 GO:0010984 regulation of lipoprotein particle clearance 1/83 33/18722 0.13648970259513 0.313342749544401 LRPAP1 1 GO:0021696 cerebellar cortex morphogenesis 1/83 33/18722 0.13648970259513 0.313342749544401 SERPINE2 1 GO:0031116 positive regulation of microtubule polymerization 1/83 33/18722 0.13648970259513 0.313342749544401 MET 1 GO:0034110 regulation of homotypic cell-cell adhesion 1/83 33/18722 0.13648970259513 0.313342749544401 SERPINE2 1 GO:0035025 positive regulation of Rho protein signal transduction 1/83 33/18722 0.13648970259513 0.313342749544401 ADGRG1 1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 1/83 33/18722 0.13648970259513 0.313342749544401 FLT1 1 GO:0048048 embryonic eye morphogenesis 1/83 33/18722 0.13648970259513 0.313342749544401 FBN2 1 GO:0050974 detection of mechanical stimulus involved in sensory perception 1/83 33/18722 0.13648970259513 0.313342749544401 SERPINE2 1 GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 1/83 33/18722 0.13648970259513 0.313342749544401 DHX36 1 GO:0071295 cellular response to vitamin 1/83 33/18722 0.13648970259513 0.313342749544401 ATP2B1 1 GO:0099174 regulation of presynapse organization 1/83 33/18722 0.13648970259513 0.313342749544401 APP 1 GO:1905606 regulation of presynapse assembly 1/83 33/18722 0.13648970259513 0.313342749544401 APP 1 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 2/83 146/18722 0.136951134023433 0.314029112772593 LGR5/ADGRG1 2 GO:0044403 biological process involved in symbiotic interaction 3/83 290/18722 0.137939856211062 0.315921495326993 JUN/GAPDH/ITGAV 3 GO:0060485 mesenchyme development 3/83 291/18722 0.138955653825813 0.317620082893597 NRP2/ENG/SEMA6A 3 GO:0010212 response to ionizing radiation 2/83 148/18722 0.139971084754261 0.317620082893597 PRKDC/PARP1 2 GO:0044272 sulfur compound biosynthetic process 2/83 148/18722 0.139971084754261 0.317620082893597 SLC26A2/ACSS1 2 GO:0044839 cell cycle G2/M phase transition 2/83 148/18722 0.139971084754261 0.317620082893597 APP/PBX1 2 GO:2001056 positive regulation of cysteine-type endopeptidase activity 2/83 148/18722 0.139971084754261 0.317620082893597 TNFSF10/EGLN3 2 GO:0010632 regulation of epithelial cell migration 3/83 292/18722 0.139974041586136 0.317620082893597 NRP2/SERPINF1/MET 3 GO:0019320 hexose catabolic process 1/83 34/18722 0.140324651211139 0.317620082893597 LRP5 1 GO:0035909 aorta morphogenesis 1/83 34/18722 0.140324651211139 0.317620082893597 ENG 1 GO:0070050 neuron cellular homeostasis 1/83 34/18722 0.140324651211139 0.317620082893597 ATP2B1 1 GO:1990000 amyloid fibril formation 1/83 34/18722 0.140324651211139 0.317620082893597 APP 1 GO:0003012 muscle system process 4/83 452/18722 0.14093753260405 0.318391750239923 ALDOA/UTRN/ATP2B1/PARP1 4 GO:0001822 kidney development 3/83 293/18722 0.140995001658238 0.318391750239923 SERPINF1/PBX1/FSTL3 3 GO:0009411 response to UV 2/83 149/18722 0.14148656087866 0.318757018856001 PARP1/DHX36 2 GO:0016525 negative regulation of angiogenesis 2/83 149/18722 0.14148656087866 0.318757018856001 SERPINF1/SEMA6A 2 GO:0070665 positive regulation of leukocyte proliferation 2/83 150/18722 0.143005622801359 0.319648775802182 IGF2/EBI3 2 GO:0050890 cognition 3/83 296/18722 0.144073137378809 0.319648775802182 JUN/APP/SERPINF1 3 GO:0001569 branching involved in blood vessel morphogenesis 1/83 35/18722 0.144142772676758 0.319648775802182 ENG 1 GO:0006084 acetyl-CoA metabolic process 1/83 35/18722 0.144142772676758 0.319648775802182 ACSS1 1 GO:0006471 protein ADP-ribosylation 1/83 35/18722 0.144142772676758 0.319648775802182 PARP1 1 GO:0032205 negative regulation of telomere maintenance 1/83 35/18722 0.144142772676758 0.319648775802182 PARP1 1 GO:0032232 negative regulation of actin filament bundle assembly 1/83 35/18722 0.144142772676758 0.319648775802182 MET 1 GO:0033146 regulation of intracellular estrogen receptor signaling pathway 1/83 35/18722 0.144142772676758 0.319648775802182 PARP1 1 GO:0033280 response to vitamin D 1/83 35/18722 0.144142772676758 0.319648775802182 ATP2B1 1 GO:0046640 regulation of alpha-beta T cell proliferation 1/83 35/18722 0.144142772676758 0.319648775802182 EBI3 1 GO:1905207 regulation of cardiocyte differentiation 1/83 35/18722 0.144142772676758 0.319648775802182 DHX36 1 GO:2000403 positive regulation of lymphocyte migration 1/83 35/18722 0.144142772676758 0.319648775802182 APP 1 GO:0030902 hindbrain development 2/83 151/18722 0.144528210062653 0.319648775802182 WLS/SERPINE2 2 GO:0071333 cellular response to glucose stimulus 2/83 151/18722 0.144528210062653 0.319648775802182 SERPINF1/LRP5 2 GO:2000181 negative regulation of blood vessel morphogenesis 2/83 151/18722 0.144528210062653 0.319648775802182 SERPINF1/SEMA6A 2 GO:2001236 regulation of extrinsic apoptotic signaling pathway 2/83 151/18722 0.144528210062653 0.319648775802182 TNFSF10/ITGAV 2 GO:1901343 negative regulation of vasculature development 2/83 152/18722 0.146054262656359 0.322045070366398 SERPINF1/SEMA6A 2 GO:0031647 regulation of protein stability 3/83 298/18722 0.146137762402316 0.322045070366398 PRKDC/GAPDH/AAK1 3 GO:0048511 rhythmic process 3/83 298/18722 0.146137762402316 0.322045070366398 JUN/PRKDC/SERPINF1 3 GO:1901990 regulation of mitotic cell cycle phase transition 3/83 299/18722 0.147173781767324 0.322045070366398 PRKDC/APP/PBX1 3 GO:0007338 single fertilization 2/83 153/18722 0.147583721027073 0.322045070366398 ALDOA/LY6K 2 GO:0071331 cellular response to hexose stimulus 2/83 153/18722 0.147583721027073 0.322045070366398 SERPINF1/LRP5 2 GO:0003203 endocardial cushion morphogenesis 1/83 36/18722 0.147944139930347 0.322045070366398 ENG 1 GO:0003230 cardiac atrium development 1/83 36/18722 0.147944139930347 0.322045070366398 ENG 1 GO:0008207 C21-steroid hormone metabolic process 1/83 36/18722 0.147944139930347 0.322045070366398 CYP11A1 1 GO:0030224 monocyte differentiation 1/83 36/18722 0.147944139930347 0.322045070366398 JUN 1 GO:0060251 regulation of glial cell proliferation 1/83 36/18722 0.147944139930347 0.322045070366398 ASCL2 1 GO:0060338 regulation of type I interferon-mediated signaling pathway 1/83 36/18722 0.147944139930347 0.322045070366398 ISG15 1 GO:0070873 regulation of glycogen metabolic process 1/83 36/18722 0.147944139930347 0.322045070366398 IGF2 1 GO:0090313 regulation of protein targeting to membrane 1/83 36/18722 0.147944139930347 0.322045070366398 TCAF1 1 GO:0009410 response to xenobiotic stimulus 4/83 462/18722 0.149051457352217 0.32350420301721 LDHA/JUN/ADIRF/ENG 4 GO:0008360 regulation of cell shape 2/83 154/18722 0.149116526067426 0.32350420301721 ALDOA/MYH10 2 GO:0071326 cellular response to monosaccharide stimulus 2/83 154/18722 0.149116526067426 0.32350420301721 SERPINF1/LRP5 2 GO:0051056 regulation of small GTPase mediated signal transduction 3/83 302/18722 0.150296453296281 0.324437853850594 ITGAV/MET/ADGRG1 3 GO:0010970 transport along microtubule 2/83 155/18722 0.150652619115369 0.324437853850594 ARMCX3/APP 2 GO:0034614 cellular response to reactive oxygen species 2/83 155/18722 0.150652619115369 0.324437853850594 JUN/MET 2 GO:0060070 canonical Wnt signaling pathway 3/83 303/18722 0.151342155533701 0.324437853850594 WLS/LGR5/LRP5 3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/83 37/18722 0.151728825598001 0.324437853850594 RPS21 1 GO:0016202 regulation of striated muscle tissue development 1/83 37/18722 0.151728825598001 0.324437853850594 IGF2 1 GO:0030513 positive regulation of BMP signaling pathway 1/83 37/18722 0.151728825598001 0.324437853850594 ENG 1 GO:0031112 positive regulation of microtubule polymerization or depolymerization 1/83 37/18722 0.151728825598001 0.324437853850594 MET 1 GO:0032885 regulation of polysaccharide biosynthetic process 1/83 37/18722 0.151728825598001 0.324437853850594 IGF2 1 GO:0033363 secretory granule organization 1/83 37/18722 0.151728825598001 0.324437853850594 SERPINE2 1 GO:0050775 positive regulation of dendrite morphogenesis 1/83 37/18722 0.151728825598001 0.324437853850594 DHX36 1 GO:0090218 positive regulation of lipid kinase activity 1/83 37/18722 0.151728825598001 0.324437853850594 FLT1 1 GO:1904358 positive regulation of telomere maintenance via telomere lengthening 1/83 37/18722 0.151728825598001 0.324437853850594 DHX36 1 GO:0002262 myeloid cell homeostasis 2/83 157/18722 0.153734436796202 0.32727826688002 PRKDC/ISG15 2 GO:0051017 actin filament bundle assembly 2/83 157/18722 0.153734436796202 0.32727826688002 PDLIM1/MET 2 GO:1902107 positive regulation of leukocyte differentiation 2/83 157/18722 0.153734436796202 0.32727826688002 JUN/PRKDC 2 GO:1903708 positive regulation of hemopoiesis 2/83 157/18722 0.153734436796202 0.32727826688002 JUN/PRKDC 2 GO:0006417 regulation of translation 4/83 468/18722 0.154006122239108 0.32742430452731 PRKDC/GAPDH/APP/DHX36 4 GO:0010613 positive regulation of cardiac muscle hypertrophy 1/83 38/18722 0.155496901994863 0.32742430452731 PARP1 1 GO:0010742 macrophage derived foam cell differentiation 1/83 38/18722 0.155496901994863 0.32742430452731 ITGAV 1 GO:0032941 secretion by tissue 1/83 38/18722 0.155496901994863 0.32742430452731 KCNN4 1 GO:0035886 vascular associated smooth muscle cell differentiation 1/83 38/18722 0.155496901994863 0.32742430452731 ENG 1 GO:0046633 alpha-beta T cell proliferation 1/83 38/18722 0.155496901994863 0.32742430452731 EBI3 1 GO:0090077 foam cell differentiation 1/83 38/18722 0.155496901994863 0.32742430452731 ITGAV 1 GO:0097242 amyloid-beta clearance 1/83 38/18722 0.155496901994863 0.32742430452731 LRPAP1 1 GO:1901031 regulation of response to reactive oxygen species 1/83 38/18722 0.155496901994863 0.32742430452731 MET 1 GO:1903580 positive regulation of ATP metabolic process 1/83 38/18722 0.155496901994863 0.32742430452731 APP 1 GO:0019221 cytokine-mediated signaling pathway 4/83 472/18722 0.157344137011037 0.330286734653877 CSF3R/KRT8/EBI3/ISG15 4 GO:0051047 positive regulation of secretion 3/83 310/18722 0.158727607129229 0.330286734653877 WLS/MYH10/KCNN4 3 GO:0060326 cell chemotaxis 3/83 310/18722 0.158727607129229 0.330286734653877 FLT1/CSF3R/MET 3 GO:0002701 negative regulation of production of molecular mediator of immune response 1/83 39/18722 0.159248441126442 0.330286734653877 PRKDC 1 GO:0010463 mesenchymal cell proliferation 1/83 39/18722 0.159248441126442 0.330286734653877 LRP5 1 GO:0014742 positive regulation of muscle hypertrophy 1/83 39/18722 0.159248441126442 0.330286734653877 PARP1 1 GO:0016233 telomere capping 1/83 39/18722 0.159248441126442 0.330286734653877 PRKDC 1 GO:0021587 cerebellum morphogenesis 1/83 39/18722 0.159248441126442 0.330286734653877 SERPINE2 1 GO:0032728 positive regulation of interferon-beta production 1/83 39/18722 0.159248441126442 0.330286734653877 ISG15 1 GO:0034314 Arp2/3 complex-mediated actin nucleation 1/83 39/18722 0.159248441126442 0.330286734653877 IQGAP2 1 GO:0071548 response to dexamethasone 1/83 39/18722 0.159248441126442 0.330286734653877 SERPINF1 1 GO:1901861 regulation of muscle tissue development 1/83 39/18722 0.159248441126442 0.330286734653877 IGF2 1 GO:1902742 apoptotic process involved in development 1/83 39/18722 0.159248441126442 0.330286734653877 LRP5 1 GO:2000249 regulation of actin cytoskeleton reorganization 1/83 39/18722 0.159248441126442 0.330286734653877 IQGAP2 1 GO:0003205 cardiac chamber development 2/83 161/18722 0.159934995918973 0.331000371639588 NRP2/ENG 2 GO:0061572 actin filament bundle organization 2/83 161/18722 0.159934995918973 0.331000371639588 PDLIM1/MET 2 GO:0034250 positive regulation of cellular amide metabolic process 2/83 162/18722 0.161492499324863 0.333509616661282 PRKDC/DHX36 2 GO:0051100 negative regulation of binding 2/83 162/18722 0.161492499324863 0.333509616661282 LRPAP1/JUN 2 GO:0010543 regulation of platelet activation 1/83 40/18722 0.162983514689923 0.334232379866787 SERPINE2 1 GO:0010863 positive regulation of phospholipase C activity 1/83 40/18722 0.162983514689923 0.334232379866787 FLT1 1 GO:0044275 cellular carbohydrate catabolic process 1/83 40/18722 0.162983514689923 0.334232379866787 AGL 1 GO:0045740 positive regulation of DNA replication 1/83 40/18722 0.162983514689923 0.334232379866787 JUN 1 GO:0046365 monosaccharide catabolic process 1/83 40/18722 0.162983514689923 0.334232379866787 LRP5 1 GO:0071276 cellular response to cadmium ion 1/83 40/18722 0.162983514689923 0.334232379866787 JUN 1 GO:0071322 cellular response to carbohydrate stimulus 2/83 163/18722 0.163052837151775 0.334232379866787 SERPINF1/LRP5 2 GO:0002700 regulation of production of molecular mediator of immune response 2/83 164/18722 0.164615954625512 0.336366427369044 PRKDC/DHX36 2 GO:0050680 negative regulation of epithelial cell proliferation 2/83 164/18722 0.164615954625512 0.336366427369044 FLT1/SERPINF1 2 GO:0050806 positive regulation of synaptic transmission 2/83 164/18722 0.164615954625512 0.336366427369044 APP/SERPINE2 2 GO:0010907 positive regulation of glucose metabolic process 1/83 41/18722 0.166702194075467 0.338127325443733 IGF2 1 GO:0032733 positive regulation of interleukin-10 production 1/83 41/18722 0.166702194075467 0.338127325443733 ISG15 1 GO:0048634 regulation of muscle organ development 1/83 41/18722 0.166702194075467 0.338127325443733 IGF2 1 GO:0050856 regulation of T cell receptor signaling pathway 1/83 41/18722 0.166702194075467 0.338127325443733 KCNN4 1 GO:0060612 adipose tissue development 1/83 41/18722 0.166702194075467 0.338127325443733 LRP5 1 GO:0071634 regulation of transforming growth factor beta production 1/83 41/18722 0.166702194075467 0.338127325443733 ITGAV 1 GO:1900371 regulation of purine nucleotide biosynthetic process 1/83 41/18722 0.166702194075467 0.338127325443733 PARP1 1 GO:0034767 positive regulation of ion transmembrane transport 2/83 167/18722 0.169321443454077 0.340632880931133 TCAF1/KCNN4 2 GO:0009416 response to light stimulus 3/83 320/18722 0.169468142535937 0.340632880931133 APP/PARP1/DHX36 3 GO:0009895 negative regulation of catabolic process 3/83 320/18722 0.169468142535937 0.340632880931133 SERPINE2/MET/DHX36 3 GO:0071496 cellular response to external stimulus 3/83 320/18722 0.169468142535937 0.340632880931133 JUN/ATP2B1/ENG 3 GO:0021575 hindbrain morphogenesis 1/83 42/18722 0.170404550367515 0.340632880931133 SERPINE2 1 GO:0021795 cerebral cortex cell migration 1/83 42/18722 0.170404550367515 0.340632880931133 ADGRG1 1 GO:0021879 forebrain neuron differentiation 1/83 42/18722 0.170404550367515 0.340632880931133 NRP2 1 GO:0030808 regulation of nucleotide biosynthetic process 1/83 42/18722 0.170404550367515 0.340632880931133 PARP1 1 GO:0032965 regulation of collagen biosynthetic process 1/83 42/18722 0.170404550367515 0.340632880931133 ENG 1 GO:0046688 response to copper ion 1/83 42/18722 0.170404550367515 0.340632880931133 APP 1 GO:0060999 positive regulation of dendritic spine development 1/83 42/18722 0.170404550367515 0.340632880931133 DHX36 1 GO:1900274 regulation of phospholipase C activity 1/83 42/18722 0.170404550367515 0.340632880931133 FLT1 1 GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II 1/83 42/18722 0.170404550367515 0.340632880931133 JUN 1 GO:2000404 regulation of T cell migration 1/83 42/18722 0.170404550367515 0.340632880931133 APP 1 GO:0099173 postsynapse organization 2/83 168/18722 0.170895140113103 0.341260646527509 NRP2/DHX36 2 GO:0009268 response to pH 1/83 43/18722 0.174090654346074 0.3423369632258 SERPINF1 1 GO:0014002 astrocyte development 1/83 43/18722 0.174090654346074 0.3423369632258 APP 1 GO:0014014 negative regulation of gliogenesis 1/83 43/18722 0.174090654346074 0.3423369632258 ASCL2 1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 1/83 43/18722 0.174090654346074 0.3423369632258 FXYD5 1 GO:0030517 negative regulation of axon extension 1/83 43/18722 0.174090654346074 0.3423369632258 SEMA6A 1 GO:0031952 regulation of protein autophosphorylation 1/83 43/18722 0.174090654346074 0.3423369632258 ENG 1 GO:0042088 T-helper 1 type immune response 1/83 43/18722 0.174090654346074 0.3423369632258 EBI3 1 GO:0045981 positive regulation of nucleotide metabolic process 1/83 43/18722 0.174090654346074 0.3423369632258 APP 1 GO:0060443 mammary gland morphogenesis 1/83 43/18722 0.174090654346074 0.3423369632258 LRP5 1 GO:0071604 transforming growth factor beta production 1/83 43/18722 0.174090654346074 0.3423369632258 ITGAV 1 GO:0098815 modulation of excitatory postsynaptic potential 1/83 43/18722 0.174090654346074 0.3423369632258 APP 1 GO:0120178 steroid hormone biosynthetic process 1/83 43/18722 0.174090654346074 0.3423369632258 CYP11A1 1 GO:1900544 positive regulation of purine nucleotide metabolic process 1/83 43/18722 0.174090654346074 0.3423369632258 APP 1 GO:1901381 positive regulation of potassium ion transmembrane transport 1/83 43/18722 0.174090654346074 0.3423369632258 KCNN4 1 GO:1903793 positive regulation of anion transport 1/83 43/18722 0.174090654346074 0.3423369632258 TCAF1 1 GO:0042129 regulation of T cell proliferation 2/83 171/18722 0.175631093349759 0.344991158987278 IGF2/EBI3 2 GO:0002831 regulation of response to biotic stimulus 3/83 327/18722 0.177111023861006 0.344991158987278 HTRA1/PRKDC/ISG15 3 GO:0007517 muscle organ development 3/83 327/18722 0.177111023861006 0.344991158987278 IGF2/UTRN/ENG 3 GO:0001678 cellular glucose homeostasis 2/83 172/18722 0.177214525862361 0.344991158987278 SERPINF1/LRP5 2 GO:1990138 neuron projection extension 2/83 172/18722 0.177214525862361 0.344991158987278 NRP2/SEMA6A 2 GO:0006378 mRNA polyadenylation 1/83 44/18722 0.177760576488013 0.344991158987278 APP 1 GO:0006775 fat-soluble vitamin metabolic process 1/83 44/18722 0.177760576488013 0.344991158987278 CYP11A1 1 GO:0007528 neuromuscular junction development 1/83 44/18722 0.177760576488013 0.344991158987278 APP 1 GO:0008542 visual learning 1/83 44/18722 0.177760576488013 0.344991158987278 APP 1 GO:0032881 regulation of polysaccharide metabolic process 1/83 44/18722 0.177760576488013 0.344991158987278 IGF2 1 GO:0046006 regulation of activated T cell proliferation 1/83 44/18722 0.177760576488013 0.344991158987278 IGF2 1 GO:0051150 regulation of smooth muscle cell differentiation 1/83 44/18722 0.177760576488013 0.344991158987278 ENG 1 GO:0060711 labyrinthine layer development 1/83 44/18722 0.177760576488013 0.344991158987278 SPINT1 1 GO:0030111 regulation of Wnt signaling pathway 3/83 328/18722 0.178210812255594 0.345518054252822 WLS/APP/LGR5 3 GO:0006694 steroid biosynthetic process 2/83 173/18722 0.178800263600713 0.345966876416596 CYP11A1/PBX1 2 GO:0010469 regulation of signaling receptor activity 2/83 173/18722 0.178800263600713 0.345966876416596 LRPAP1/APP 2 GO:0048639 positive regulation of developmental growth 2/83 174/18722 0.180388255866164 0.346515820167782 IGF2/PRKDC 2 GO:0070371 ERK1 and ERK2 cascade 3/83 330/18722 0.180416175329388 0.346515820167782 APP/ITGAV/SEMA6A 3 GO:0003197 endocardial cushion development 1/83 45/18722 0.181414386968337 0.346515820167782 ENG 1 GO:0003254 regulation of membrane depolarization 1/83 45/18722 0.181414386968337 0.346515820167782 PARP1 1 GO:0006110 regulation of glycolytic process 1/83 45/18722 0.181414386968337 0.346515820167782 APP 1 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 1/83 45/18722 0.181414386968337 0.346515820167782 PARP1 1 GO:0030850 prostate gland development 1/83 45/18722 0.181414386968337 0.346515820167782 SERPINF1 1 GO:0031670 cellular response to nutrient 1/83 45/18722 0.181414386968337 0.346515820167782 ATP2B1 1 GO:0035384 thioester biosynthetic process 1/83 45/18722 0.181414386968337 0.346515820167782 ACSS1 1 GO:0035987 endodermal cell differentiation 1/83 45/18722 0.181414386968337 0.346515820167782 ITGAV 1 GO:0042551 neuron maturation 1/83 45/18722 0.181414386968337 0.346515820167782 APP 1 GO:0043631 RNA polyadenylation 1/83 45/18722 0.181414386968337 0.346515820167782 APP 1 GO:0071616 acyl-CoA biosynthetic process 1/83 45/18722 0.181414386968337 0.346515820167782 ACSS1 1 GO:0010634 positive regulation of epithelial cell migration 2/83 176/18722 0.183570803150936 0.350288610553564 NRP2/MET 2 GO:0062012 regulation of small molecule metabolic process 3/83 334/18722 0.184849559119784 0.35067956681874 IGF2/APP/PARP1 3 GO:0006383 transcription by RNA polymerase III 1/83 46/18722 0.185052155661469 0.35067956681874 DHX36 1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 1/83 46/18722 0.185052155661469 0.35067956681874 TENM3 1 GO:0031648 protein destabilization 1/83 46/18722 0.185052155661469 0.35067956681874 PRKDC 1 GO:0032924 activin receptor signaling pathway 1/83 46/18722 0.185052155661469 0.35067956681874 FSTL3 1 GO:0055010 ventricular cardiac muscle tissue morphogenesis 1/83 46/18722 0.185052155661469 0.35067956681874 ENG 1 GO:1900271 regulation of long-term synaptic potentiation 1/83 46/18722 0.185052155661469 0.35067956681874 APP 1 GO:0006109 regulation of carbohydrate metabolic process 2/83 178/18722 0.186761769962351 0.35067956681874 IGF2/APP 2 GO:0035725 sodium ion transmembrane transport 2/83 178/18722 0.186761769962351 0.35067956681874 UTRN/FXYD5 2 GO:0048015 phosphatidylinositol-mediated signaling 2/83 178/18722 0.186761769962351 0.35067956681874 FLT1/SERPINE2 2 GO:0007265 Ras protein signal transduction 3/83 337/18722 0.188193875827752 0.35067956681874 JUN/MET/ADGRG1 3 GO:0010950 positive regulation of endopeptidase activity 2/83 179/18722 0.188360288086201 0.35067956681874 TNFSF10/EGLN3 2 GO:0001774 microglial cell activation 1/83 47/18722 0.188673952142519 0.35067956681874 APP 1 GO:0010712 regulation of collagen metabolic process 1/83 47/18722 0.188673952142519 0.35067956681874 ENG 1 GO:0010761 fibroblast migration 1/83 47/18722 0.188673952142519 0.35067956681874 PDLIM1 1 GO:0010799 regulation of peptidyl-threonine phosphorylation 1/83 47/18722 0.188673952142519 0.35067956681874 APP 1 GO:0032369 negative regulation of lipid transport 1/83 47/18722 0.188673952142519 0.35067956681874 ITGAV 1 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 1/83 47/18722 0.188673952142519 0.35067956681874 JUN 1 GO:0045332 phospholipid translocation 1/83 47/18722 0.188673952142519 0.35067956681874 KCNN4 1 GO:0045601 regulation of endothelial cell differentiation 1/83 47/18722 0.188673952142519 0.35067956681874 BTG1 1 GO:0045747 positive regulation of Notch signaling pathway 1/83 47/18722 0.188673952142519 0.35067956681874 AAK1 1 GO:0045911 positive regulation of DNA recombination 1/83 47/18722 0.188673952142519 0.35067956681874 PARP1 1 GO:0048483 autonomic nervous system development 1/83 47/18722 0.188673952142519 0.35067956681874 NRP2 1 GO:0050798 activated T cell proliferation 1/83 47/18722 0.188673952142519 0.35067956681874 IGF2 1 GO:0050885 neuromuscular process controlling balance 1/83 47/18722 0.188673952142519 0.35067956681874 APP 1 GO:0061001 regulation of dendritic spine morphogenesis 1/83 47/18722 0.188673952142519 0.35067956681874 DHX36 1 GO:0072583 clathrin-dependent endocytosis 1/83 47/18722 0.188673952142519 0.35067956681874 AAK1 1 GO:0018209 peptidyl-serine modification 3/83 338/18722 0.189312228017142 0.351527893138458 PRKDC/APP/PARP1 3 GO:0010721 negative regulation of cell development 2/83 180/18722 0.189960764733208 0.351718542365222 ASCL2/SEMA6A 2 GO:0015698 inorganic anion transport 2/83 180/18722 0.189960764733208 0.351718542365222 SLC26A2/CLIC3 2 GO:0048660 regulation of smooth muscle cell proliferation 2/83 180/18722 0.189960764733208 0.351718542365222 JUN/PRKDC 2 GO:0006790 sulfur compound metabolic process 3/83 339/18722 0.190432341464071 0.352254273732105 SLC26A2/CLIC3/ACSS1 3 GO:0008361 regulation of cell size 2/83 181/18722 0.191563151911727 0.353978039729498 KCNN4/SEMA6A 2 GO:0010569 regulation of double-strand break repair via homologous recombination 1/83 48/18722 0.192279845688553 0.353978039729498 PARP1 1 GO:0048146 positive regulation of fibroblast proliferation 1/83 48/18722 0.192279845688553 0.353978039729498 PRKDC 1 GO:0090199 regulation of release of cytochrome c from mitochondria 1/83 48/18722 0.192279845688553 0.353978039729498 TNFSF10 1 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 1/83 48/18722 0.192279845688553 0.353978039729498 TNFSF10 1 GO:0048017 inositol lipid-mediated signaling 2/83 182/18722 0.19316740200734 0.355174978335785 FLT1/SERPINE2 2 GO:0001933 negative regulation of protein phosphorylation 3/83 342/18722 0.193803077575128 0.355174978335785 PRKDC/LRP5/ENG 3 GO:0000959 mitochondrial RNA metabolic process 1/83 49/18722 0.195869905279848 0.355174978335785 TFAM 1 GO:0002762 negative regulation of myeloid leukocyte differentiation 1/83 49/18722 0.195869905279848 0.355174978335785 FSTL3 1 GO:0008038 neuron recognition 1/83 49/18722 0.195869905279848 0.355174978335785 APP 1 GO:0009994 oocyte differentiation 1/83 49/18722 0.195869905279848 0.355174978335785 LGR5 1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 1/83 49/18722 0.195869905279848 0.355174978335785 ENG 1 GO:0018198 peptidyl-cysteine modification 1/83 49/18722 0.195869905279848 0.355174978335785 GAPDH 1 GO:0021695 cerebellar cortex development 1/83 49/18722 0.195869905279848 0.355174978335785 SERPINE2 1 GO:0030195 negative regulation of blood coagulation 1/83 49/18722 0.195869905279848 0.355174978335785 SERPINE2 1 GO:0043330 response to exogenous dsRNA 1/83 49/18722 0.195869905279848 0.355174978335785 DHX36 1 GO:0046580 negative regulation of Ras protein signal transduction 1/83 49/18722 0.195869905279848 0.355174978335785 MET 1 GO:0048168 regulation of neuronal synaptic plasticity 1/83 49/18722 0.195869905279848 0.355174978335785 APP 1 GO:0050832 defense response to fungus 1/83 49/18722 0.195869905279848 0.355174978335785 GAPDH 1 GO:0052372 modulation by symbiont of entry into host 1/83 49/18722 0.195869905279848 0.355174978335785 ITGAV 1 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 1/83 49/18722 0.195869905279848 0.355174978335785 JUN 1 GO:0048659 smooth muscle cell proliferation 2/83 184/18722 0.196381302364345 0.35576856370223 JUN/PRKDC 2 GO:0007632 visual behavior 1/83 50/18722 0.199444199601156 0.357581876277291 APP 1 GO:0019083 viral transcription 1/83 50/18722 0.199444199601156 0.357581876277291 JUN 1 GO:0030490 maturation of SSU-rRNA 1/83 50/18722 0.199444199601156 0.357581876277291 RPS21 1 GO:0043268 positive regulation of potassium ion transport 1/83 50/18722 0.199444199601156 0.357581876277291 KCNN4 1 GO:0043628 ncRNA 3'-end processing 1/83 50/18722 0.199444199601156 0.357581876277291 RPS21 1 GO:0051646 mitochondrion localization 1/83 50/18722 0.199444199601156 0.357581876277291 ARMCX3 1 GO:0060337 type I interferon signaling pathway 1/83 50/18722 0.199444199601156 0.357581876277291 ISG15 1 GO:0099054 presynapse assembly 1/83 50/18722 0.199444199601156 0.357581876277291 APP 1 GO:1900047 negative regulation of hemostasis 1/83 50/18722 0.199444199601156 0.357581876277291 SERPINE2 1 GO:2000677 regulation of transcription regulatory region DNA binding 1/83 50/18722 0.199444199601156 0.357581876277291 PARP1 1 GO:0006936 muscle contraction 3/83 347/18722 0.199454597242587 0.357581876277291 ALDOA/UTRN/ATP2B1 3 GO:0008217 regulation of blood pressure 2/83 186/18722 0.199602092345161 0.357581876277291 ATP2B1/LRP5 2 GO:0033044 regulation of chromosome organization 2/83 187/18722 0.20121495585046 0.360137508943463 PARP1/DHX36 2 GO:0042742 defense response to bacterium 3/83 350/18722 0.202864935903341 0.360665814966925 PLAC8/ISG15/PRG2 3 GO:0009948 anterior/posterior axis specification 1/83 51/18722 0.203002797042946 0.360665814966925 WLS 1 GO:0014009 glial cell proliferation 1/83 51/18722 0.203002797042946 0.360665814966925 ASCL2 1 GO:0021872 forebrain generation of neurons 1/83 51/18722 0.203002797042946 0.360665814966925 NRP2 1 GO:0032964 collagen biosynthetic process 1/83 51/18722 0.203002797042946 0.360665814966925 ENG 1 GO:0045661 regulation of myoblast differentiation 1/83 51/18722 0.203002797042946 0.360665814966925 BTG1 1 GO:0045668 negative regulation of osteoblast differentiation 1/83 51/18722 0.203002797042946 0.360665814966925 LRP5 1 GO:0050982 detection of mechanical stimulus 1/83 51/18722 0.203002797042946 0.360665814966925 SERPINE2 1 GO:0046578 regulation of Ras protein signal transduction 2/83 189/18722 0.204445392890707 0.361314900545912 MET/ADGRG1 2 GO:0009566 fertilization 2/83 190/18722 0.20606287670777 0.361314900545912 ALDOA/LY6K 2 GO:0009755 hormone-mediated signaling pathway 2/83 190/18722 0.20606287670777 0.361314900545912 LGR5/PARP1 2 GO:0099111 microtubule-based transport 2/83 190/18722 0.20606287670777 0.361314900545912 ARMCX3/APP 2 GO:0031346 positive regulation of cell projection organization 3/83 353/18722 0.206289286630755 0.361314900545912 TENM3/SERPINF1/DHX36 3 GO:0002218 activation of innate immune response 1/83 52/18722 0.206545765702655 0.361314900545912 PRKDC 1 GO:0010718 positive regulation of epithelial to mesenchymal transition 1/83 52/18722 0.206545765702655 0.361314900545912 ENG 1 GO:0021545 cranial nerve development 1/83 52/18722 0.206545765702655 0.361314900545912 NRP2 1 GO:0032206 positive regulation of telomere maintenance 1/83 52/18722 0.206545765702655 0.361314900545912 DHX36 1 GO:0034204 lipid translocation 1/83 52/18722 0.206545765702655 0.361314900545912 KCNN4 1 GO:0043277 apoptotic cell clearance 1/83 52/18722 0.206545765702655 0.361314900545912 ITGAV 1 GO:0043392 negative regulation of DNA binding 1/83 52/18722 0.206545765702655 0.361314900545912 JUN 1 GO:0045010 actin nucleation 1/83 52/18722 0.206545765702655 0.361314900545912 IQGAP2 1 GO:0071357 cellular response to type I interferon 1/83 52/18722 0.206545765702655 0.361314900545912 ISG15 1 GO:0072132 mesenchyme morphogenesis 1/83 52/18722 0.206545765702655 0.361314900545912 ENG 1 GO:1903426 regulation of reactive oxygen species biosynthetic process 1/83 52/18722 0.206545765702655 0.361314900545912 PAGE4 1 GO:2000378 negative regulation of reactive oxygen species metabolic process 1/83 52/18722 0.206545765702655 0.361314900545912 PAGE4 1 GO:0050821 protein stabilization 2/83 191/18722 0.207681811506847 0.362973726620918 GAPDH/AAK1 2 GO:0032872 regulation of stress-activated MAPK cascade 2/83 192/18722 0.20930215331963 0.363537550720677 APP/PAGE4 2 GO:2001233 regulation of apoptotic signaling pathway 3/83 356/18722 0.209727195847955 0.363537550720677 TNFSF10/ITGAV/PARP1 3 GO:0008347 glial cell migration 1/83 53/18722 0.210073173385927 0.363537550720677 ADGRG1 1 GO:0034381 plasma lipoprotein particle clearance 1/83 53/18722 0.210073173385927 0.363537550720677 LRPAP1 1 GO:0043620 regulation of DNA-templated transcription in response to stress 1/83 53/18722 0.210073173385927 0.363537550720677 JUN 1 GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 1/83 53/18722 0.210073173385927 0.363537550720677 MET 1 GO:0050819 negative regulation of coagulation 1/83 53/18722 0.210073173385927 0.363537550720677 SERPINE2 1 GO:0071320 cellular response to cAMP 1/83 53/18722 0.210073173385927 0.363537550720677 APP 1 GO:0099172 presynapse organization 1/83 53/18722 0.210073173385927 0.363537550720677 APP 1 GO:1990090 cellular response to nerve growth factor stimulus 1/83 53/18722 0.210073173385927 0.363537550720677 APP 1 GO:2000772 regulation of cellular senescence 1/83 53/18722 0.210073173385927 0.363537550720677 PRKDC 1 GO:0050777 negative regulation of immune response 2/83 194/18722 0.212546883872224 0.366660723220215 HTRA1/ISG15 2 GO:0051052 regulation of DNA metabolic process 3/83 359/18722 0.213178212687165 0.366660723220215 PRKDC/PARP1/DHX36 3 GO:0071900 regulation of protein serine/threonine kinase activity 3/83 359/18722 0.213178212687165 0.366660723220215 IGF2/FLT1/LRP5 3 GO:0001706 endoderm formation 1/83 54/18722 0.213585087607844 0.366660723220215 ITGAV 1 GO:0007215 glutamate receptor signaling pathway 1/83 54/18722 0.213585087607844 0.366660723220215 APP 1 GO:0030520 intracellular estrogen receptor signaling pathway 1/83 54/18722 0.213585087607844 0.366660723220215 PARP1 1 GO:0072348 sulfur compound transport 1/83 54/18722 0.213585087607844 0.366660723220215 SLC26A2 1 GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II 1/83 54/18722 0.213585087607844 0.366660723220215 JUN 1 GO:2000179 positive regulation of neural precursor cell proliferation 1/83 54/18722 0.213585087607844 0.366660723220215 ADGRG1 1 GO:0030705 cytoskeleton-dependent intracellular transport 2/83 195/18722 0.214171186427997 0.367014985252941 ARMCX3/APP 2 GO:0070302 regulation of stress-activated protein kinase signaling cascade 2/83 195/18722 0.214171186427997 0.367014985252941 APP/PAGE4 2 GO:0022408 negative regulation of cell-cell adhesion 2/83 196/18722 0.215796723625043 0.36849387523605 SERPINE2/FXYD5 2 GO:0043393 regulation of protein binding 2/83 196/18722 0.215796723625043 0.36849387523605 LRPAP1/APP 2 GO:0045664 regulation of neuron differentiation 2/83 196/18722 0.215796723625043 0.36849387523605 APP/PBX1 2 GO:0071674 mononuclear cell migration 2/83 196/18722 0.215796723625043 0.36849387523605 FLT1/APP 2 GO:0051251 positive regulation of lymphocyte activation 3/83 362/18722 0.216641889081918 0.368733467155985 IGF2/PRKDC/EBI3 3 GO:0003229 ventricular cardiac muscle tissue development 1/83 55/18722 0.21708157559416 0.368733467155985 ENG 1 GO:0010676 positive regulation of cellular carbohydrate metabolic process 1/83 55/18722 0.21708157559416 0.368733467155985 IGF2 1 GO:0031113 regulation of microtubule polymerization 1/83 55/18722 0.21708157559416 0.368733467155985 MET 1 GO:0043331 response to dsRNA 1/83 55/18722 0.21708157559416 0.368733467155985 DHX36 1 GO:0061614 pri-miRNA transcription by RNA polymerase II 1/83 55/18722 0.21708157559416 0.368733467155985 JUN 1 GO:0042594 response to starvation 2/83 197/18722 0.217423453234575 0.368989934242698 JUN/PAGE4 2 GO:0048167 regulation of synaptic plasticity 2/83 198/18722 0.219051333369221 0.369009570376787 APP/SERPINE2 2 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1/83 56/18722 0.220562704282524 0.369009570376787 DHX36 1 GO:0001658 branching involved in ureteric bud morphogenesis 1/83 56/18722 0.220562704282524 0.369009570376787 PBX1 1 GO:0002090 regulation of receptor internalization 1/83 56/18722 0.220562704282524 0.369009570376787 LRPAP1 1 GO:0002886 regulation of myeloid leukocyte mediated immunity 1/83 56/18722 0.220562704282524 0.369009570376787 DHX36 1 GO:0010518 positive regulation of phospholipase activity 1/83 56/18722 0.220562704282524 0.369009570376787 FLT1 1 GO:0022029 telencephalon cell migration 1/83 56/18722 0.220562704282524 0.369009570376787 ADGRG1 1 GO:0032608 interferon-beta production 1/83 56/18722 0.220562704282524 0.369009570376787 ISG15 1 GO:0032648 regulation of interferon-beta production 1/83 56/18722 0.220562704282524 0.369009570376787 ISG15 1 GO:0042733 embryonic digit morphogenesis 1/83 56/18722 0.220562704282524 0.369009570376787 LRP5 1 GO:0043388 positive regulation of DNA binding 1/83 56/18722 0.220562704282524 0.369009570376787 PARP1 1 GO:0043470 regulation of carbohydrate catabolic process 1/83 56/18722 0.220562704282524 0.369009570376787 APP 1 GO:0045071 negative regulation of viral genome replication 1/83 56/18722 0.220562704282524 0.369009570376787 ISG15 1 GO:0046622 positive regulation of organ growth 1/83 56/18722 0.220562704282524 0.369009570376787 IGF2 1 GO:0051058 negative regulation of small GTPase mediated signal transduction 1/83 56/18722 0.220562704282524 0.369009570376787 MET 1 GO:1990089 response to nerve growth factor 1/83 56/18722 0.220562704282524 0.369009570376787 APP 1 GO:0042098 T cell proliferation 2/83 199/18722 0.220680322480893 0.369009570376787 IGF2/EBI3 2 GO:0071902 positive regulation of protein serine/threonine kinase activity 2/83 200/18722 0.222310379358663 0.370991913346886 IGF2/FLT1 2 GO:0009615 response to virus 3/83 367/18722 0.222441607640476 0.370991913346886 HTRA1/ISG15/DHX36 3 GO:0140694 non-membrane-bounded organelle assembly 3/83 367/18722 0.222441607640476 0.370991913346886 KRT19/KRT8/PRKDC 3 GO:0010883 regulation of lipid storage 1/83 57/18722 0.224028540323698 0.371714307678719 ITGAV 1 GO:0016447 somatic recombination of immunoglobulin gene segments 1/83 57/18722 0.224028540323698 0.371714307678719 PRKDC 1 GO:0050891 multicellular organismal water homeostasis 1/83 57/18722 0.224028540323698 0.371714307678719 MET 1 GO:0051155 positive regulation of striated muscle cell differentiation 1/83 57/18722 0.224028540323698 0.371714307678719 MORF4L2 1 GO:0051289 protein homotetramerization 1/83 57/18722 0.224028540323698 0.371714307678719 ALDOA 1 GO:0060042 retina morphogenesis in camera-type eye 1/83 57/18722 0.224028540323698 0.371714307678719 LRP5 1 GO:0050900 leukocyte migration 3/83 369/18722 0.224770537169076 0.372625598926093 FLT1/CSF3R/APP 3 GO:0016051 carbohydrate biosynthetic process 2/83 202/18722 0.225573533241936 0.37363636654384 IGF2/AGL 2 GO:0001954 positive regulation of cell-matrix adhesion 1/83 58/18722 0.227479150082773 0.373909181215986 UTRN 1 GO:0002763 positive regulation of myeloid leukocyte differentiation 1/83 58/18722 0.227479150082773 0.373909181215986 JUN 1 GO:0006826 iron ion transport 1/83 58/18722 0.227479150082773 0.373909181215986 SLC40A1 1 GO:0010043 response to zinc ion 1/83 58/18722 0.227479150082773 0.373909181215986 PARP1 1 GO:0018208 peptidyl-proline modification 1/83 58/18722 0.227479150082773 0.373909181215986 EGLN3 1 GO:0034340 response to type I interferon 1/83 58/18722 0.227479150082773 0.373909181215986 ISG15 1 GO:0035904 aorta development 1/83 58/18722 0.227479150082773 0.373909181215986 ENG 1 GO:0043525 positive regulation of neuron apoptotic process 1/83 58/18722 0.227479150082773 0.373909181215986 JUN 1 GO:0097035 regulation of membrane lipid distribution 1/83 58/18722 0.227479150082773 0.373909181215986 KCNN4 1 GO:0045862 positive regulation of proteolysis 3/83 372/18722 0.228273213774294 0.374895600871462 TNFSF10/APP/EGLN3 3 GO:0021885 forebrain cell migration 1/83 59/18722 0.230914599640377 0.378269424665126 ADGRG1 1 GO:0043551 regulation of phosphatidylinositol 3-kinase activity 1/83 59/18722 0.230914599640377 0.378269424665126 FLT1 1 GO:0048010 vascular endothelial growth factor receptor signaling pathway 1/83 59/18722 0.230914599640377 0.378269424665126 FLT1 1 GO:0009620 response to fungus 1/83 60/18722 0.234334954793881 0.382252715288246 GAPDH 1 GO:0031638 zymogen activation 1/83 60/18722 0.234334954793881 0.382252715288246 SERPINE2 1 GO:0051851 modulation by host of symbiont process 1/83 60/18722 0.234334954793881 0.382252715288246 JUN 1 GO:0055008 cardiac muscle tissue morphogenesis 1/83 60/18722 0.234334954793881 0.382252715288246 ENG 1 GO:1903670 regulation of sprouting angiogenesis 1/83 60/18722 0.234334954793881 0.382252715288246 SEMA6A 1 GO:0030900 forebrain development 3/83 379/18722 0.236487194962876 0.384884391362032 NRP2/APP/ADGRG1 3 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 2/83 209/18722 0.237022305127783 0.384884391362032 TNFSF10/EGLN3 2 GO:0030199 collagen fibril organization 1/83 61/18722 0.237740281058596 0.384884391362032 COL14A1 1 GO:0034113 heterotypic cell-cell adhesion 1/83 61/18722 0.237740281058596 0.384884391362032 ITGAV 1 GO:0042255 ribosome assembly 1/83 61/18722 0.237740281058596 0.384884391362032 PRKDC 1 GO:0060997 dendritic spine morphogenesis 1/83 61/18722 0.237740281058596 0.384884391362032 DHX36 1 GO:0060998 regulation of dendritic spine development 1/83 61/18722 0.237740281058596 0.384884391362032 DHX36 1 GO:0090342 regulation of cell aging 1/83 61/18722 0.237740281058596 0.384884391362032 PRKDC 1 GO:2000401 regulation of lymphocyte migration 1/83 61/18722 0.237740281058596 0.384884391362032 APP 1 GO:0007623 circadian rhythm 2/83 210/18722 0.238660845746584 0.38605139316163 JUN/PRKDC 2 GO:0032535 regulation of cellular component size 3/83 382/18722 0.240024039631088 0.387130842368865 KCNN4/IQGAP2/SEMA6A 3 GO:1902903 regulation of supramolecular fiber organization 3/83 382/18722 0.240024039631088 0.387130842368865 IQGAP2/APP/MET 3 GO:0010573 vascular endothelial growth factor production 1/83 62/18722 0.241130643668967 0.387130842368865 ADGRG1 1 GO:0032613 interleukin-10 production 1/83 62/18722 0.241130643668967 0.387130842368865 ISG15 1 GO:0032653 regulation of interleukin-10 production 1/83 62/18722 0.241130643668967 0.387130842368865 ISG15 1 GO:0032731 positive regulation of interleukin-1 beta production 1/83 62/18722 0.241130643668967 0.387130842368865 APP 1 GO:0048002 antigen processing and presentation of peptide antigen 1/83 62/18722 0.241130643668967 0.387130842368865 HLA-C 1 GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 1/83 62/18722 0.241130643668967 0.387130842368865 ENG 1 GO:0060675 ureteric bud morphogenesis 1/83 62/18722 0.241130643668967 0.387130842368865 PBX1 1 GO:0042326 negative regulation of phosphorylation 3/83 385/18722 0.243570210545383 0.39028101234656 PRKDC/LRP5/ENG 3 GO:0001756 somitogenesis 1/83 63/18722 0.244506107579764 0.39028101234656 PRKDC 1 GO:0001947 heart looping 1/83 63/18722 0.244506107579764 0.39028101234656 ENG 1 GO:0050854 regulation of antigen receptor-mediated signaling pathway 1/83 63/18722 0.244506107579764 0.39028101234656 KCNN4 1 GO:0072171 mesonephric tubule morphogenesis 1/83 63/18722 0.244506107579764 0.39028101234656 PBX1 1 GO:0099601 regulation of neurotransmitter receptor activity 1/83 63/18722 0.244506107579764 0.39028101234656 APP 1 GO:2000242 negative regulation of reproductive process 1/83 63/18722 0.244506107579764 0.39028101234656 SERPINF1 1 GO:0031669 cellular response to nutrient levels 2/83 215/18722 0.246862348508058 0.391443140134169 JUN/ATP2B1 2 GO:0001885 endothelial cell development 1/83 64/18722 0.247866737467265 0.391443140134169 MET 1 GO:0006749 glutathione metabolic process 1/83 64/18722 0.247866737467265 0.391443140134169 CLIC3 1 GO:0006940 regulation of smooth muscle contraction 1/83 64/18722 0.247866737467265 0.391443140134169 ATP2B1 1 GO:0030104 water homeostasis 1/83 64/18722 0.247866737467265 0.391443140134169 MET 1 GO:0030858 positive regulation of epithelial cell differentiation 1/83 64/18722 0.247866737467265 0.391443140134169 BTG1 1 GO:0045670 regulation of osteoclast differentiation 1/83 64/18722 0.247866737467265 0.391443140134169 FSTL3 1 GO:0045995 regulation of embryonic development 1/83 64/18722 0.247866737467265 0.391443140134169 DHX36 1 GO:0046579 positive regulation of Ras protein signal transduction 1/83 64/18722 0.247866737467265 0.391443140134169 ADGRG1 1 GO:0050771 negative regulation of axonogenesis 1/83 64/18722 0.247866737467265 0.391443140134169 SEMA6A 1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 1/83 64/18722 0.247866737467265 0.391443140134169 LRP5 1 GO:0098930 axonal transport 1/83 64/18722 0.247866737467265 0.391443140134169 ARMCX3 1 GO:1903409 reactive oxygen species biosynthetic process 1/83 64/18722 0.247866737467265 0.391443140134169 PAGE4 1 GO:0050870 positive regulation of T cell activation 2/83 216/18722 0.248504152033501 0.392129408882252 IGF2/EBI3 2 GO:1901987 regulation of cell cycle phase transition 3/83 390/18722 0.249500079945658 0.393311809406257 PRKDC/APP/PBX1 3 GO:0007596 blood coagulation 2/83 217/18722 0.250146372324232 0.393311809406257 F5/SERPINE2 2 GO:0002720 positive regulation of cytokine production involved in immune response 1/83 65/18722 0.251212597730434 0.393311809406257 DHX36 1 GO:0038034 signal transduction in absence of ligand 1/83 65/18722 0.251212597730434 0.393311809406257 ITGAV 1 GO:0043489 RNA stabilization 1/83 65/18722 0.251212597730434 0.393311809406257 DHX36 1 GO:0060389 pathway-restricted SMAD protein phosphorylation 1/83 65/18722 0.251212597730434 0.393311809406257 ENG 1 GO:0070613 regulation of protein processing 1/83 65/18722 0.251212597730434 0.393311809406257 SERPINE2 1 GO:0071677 positive regulation of mononuclear cell migration 1/83 65/18722 0.251212597730434 0.393311809406257 APP 1 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 1/83 65/18722 0.251212597730434 0.393311809406257 ITGAV 1 GO:0045088 regulation of innate immune response 2/83 218/18722 0.2517889738884 0.393311809406257 PRKDC/ISG15 2 GO:0034764 positive regulation of transmembrane transport 2/83 219/18722 0.253431921533158 0.393311809406257 TCAF1/KCNN4 2 GO:2001020 regulation of response to DNA damage stimulus 2/83 219/18722 0.253431921533158 0.393311809406257 PRKDC/PARP1 2 GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 1/83 66/18722 0.254543752492099 0.393311809406257 PRKDC 1 GO:0006303 double-strand break repair via nonhomologous end joining 1/83 66/18722 0.254543752492099 0.393311809406257 PRKDC 1 GO:0016444 somatic cell DNA recombination 1/83 66/18722 0.254543752492099 0.393311809406257 PRKDC 1 GO:0019229 regulation of vasoconstriction 1/83 66/18722 0.254543752492099 0.393311809406257 ATP2B1 1 GO:0030193 regulation of blood coagulation 1/83 66/18722 0.254543752492099 0.393311809406257 SERPINE2 1 GO:0042446 hormone biosynthetic process 1/83 66/18722 0.254543752492099 0.393311809406257 CYP11A1 1 GO:0046626 regulation of insulin receptor signaling pathway 1/83 66/18722 0.254543752492099 0.393311809406257 IGF2 1 GO:0050918 positive chemotaxis 1/83 66/18722 0.254543752492099 0.393311809406257 MET 1 GO:0050922 negative regulation of chemotaxis 1/83 66/18722 0.254543752492099 0.393311809406257 SEMA6A 1 GO:0071300 cellular response to retinoic acid 1/83 66/18722 0.254543752492099 0.393311809406257 SERPINF1 1 GO:0072678 T cell migration 1/83 66/18722 0.254543752492099 0.393311809406257 APP 1 GO:1902476 chloride transmembrane transport 1/83 66/18722 0.254543752492099 0.393311809406257 SLC26A2 1 GO:1905953 negative regulation of lipid localization 1/83 66/18722 0.254543752492099 0.393311809406257 ITGAV 1 GO:2000272 negative regulation of signaling receptor activity 1/83 66/18722 0.254543752492099 0.393311809406257 LRPAP1 1 GO:0002064 epithelial cell development 2/83 220/18722 0.255075180362761 0.393503849673757 ADAMTSL4/MET 2 GO:0097529 myeloid leukocyte migration 2/83 220/18722 0.255075180362761 0.393503849673757 FLT1/CSF3R 2 GO:0006879 cellular iron ion homeostasis 1/83 67/18722 0.257860265600115 0.394338523263468 SLC40A1 1 GO:0009880 embryonic pattern specification 1/83 67/18722 0.257860265600115 0.394338523263468 NRP2 1 GO:0010517 regulation of phospholipase activity 1/83 67/18722 0.257860265600115 0.394338523263468 FLT1 1 GO:0016445 somatic diversification of immunoglobulins 1/83 67/18722 0.257860265600115 0.394338523263468 PRKDC 1 GO:0043967 histone H4 acetylation 1/83 67/18722 0.257860265600115 0.394338523263468 MORF4L2 1 GO:0046635 positive regulation of alpha-beta T cell activation 1/83 67/18722 0.257860265600115 0.394338523263468 EBI3 1 GO:0048814 regulation of dendrite morphogenesis 1/83 67/18722 0.257860265600115 0.394338523263468 DHX36 1 GO:0061180 mammary gland epithelium development 1/83 67/18722 0.257860265600115 0.394338523263468 LRP5 1 GO:0061371 determination of heart left/right asymmetry 1/83 67/18722 0.257860265600115 0.394338523263468 ENG 1 GO:0070527 platelet aggregation 1/83 67/18722 0.257860265600115 0.394338523263468 SERPINE2 1 GO:1903317 regulation of protein maturation 1/83 67/18722 0.257860265600115 0.394338523263468 SERPINE2 1 GO:0007599 hemostasis 2/83 222/18722 0.258362493467749 0.394482385365844 F5/SERPINE2 2 GO:0050817 coagulation 2/83 222/18722 0.258362493467749 0.394482385365844 F5/SERPINE2 2 GO:0050920 regulation of chemotaxis 2/83 223/18722 0.260006479420238 0.396679182888176 MET/SEMA6A 2 GO:0031640 killing of cells of other organism 1/83 68/18722 0.261162200628536 0.396876205829371 GAPDH 1 GO:0042698 ovulation cycle 1/83 68/18722 0.261162200628536 0.396876205829371 SERPINF1 1 GO:0046686 response to cadmium ion 1/83 68/18722 0.261162200628536 0.396876205829371 JUN 1 GO:0051148 negative regulation of muscle cell differentiation 1/83 68/18722 0.261162200628536 0.396876205829371 IGF2 1 GO:1900046 regulation of hemostasis 1/83 68/18722 0.261162200628536 0.396876205829371 SERPINE2 1 GO:0006364 rRNA processing 2/83 225/18722 0.263294941492903 0.398737220872589 RPS21/PRKDC 2 GO:0016485 protein processing 2/83 225/18722 0.263294941492903 0.398737220872589 SERPINE2/PARP1 2 GO:0050670 regulation of lymphocyte proliferation 2/83 225/18722 0.263294941492903 0.398737220872589 IGF2/EBI3 2 GO:0003143 embryonic heart tube morphogenesis 1/83 69/18722 0.264449620878769 0.398737220872589 ENG 1 GO:0010611 regulation of cardiac muscle hypertrophy 1/83 69/18722 0.264449620878769 0.398737220872589 PARP1 1 GO:0034605 cellular response to heat 1/83 69/18722 0.264449620878769 0.398737220872589 DHX36 1 GO:0050688 regulation of defense response to virus 1/83 69/18722 0.264449620878769 0.398737220872589 HTRA1 1 GO:0051966 regulation of synaptic transmission, glutamatergic 1/83 69/18722 0.264449620878769 0.398737220872589 SERPINE2 1 GO:0060193 positive regulation of lipase activity 1/83 69/18722 0.264449620878769 0.398737220872589 FLT1 1 GO:1901224 positive regulation of NIK/NF-kappaB signaling 1/83 69/18722 0.264449620878769 0.398737220872589 APP 1 GO:0051495 positive regulation of cytoskeleton organization 2/83 226/18722 0.264939351022379 0.399164275546578 IQGAP2/MET 2 GO:0032944 regulation of mononuclear cell proliferation 2/83 227/18722 0.266583835628223 0.40132909211009 IGF2/EBI3 2 GO:0002548 monocyte chemotaxis 1/83 70/18722 0.267722589380729 0.402103935721017 FLT1 1 GO:0003407 neural retina development 1/83 70/18722 0.267722589380729 0.402103935721017 ATP2B1 1 GO:0060415 muscle tissue morphogenesis 1/83 70/18722 0.267722589380729 0.402103935721017 ENG 1 GO:0000281 mitotic cytokinesis 1/83 71/18722 0.270981168893993 0.404171758851919 MYH10 1 GO:0003208 cardiac ventricle morphogenesis 1/83 71/18722 0.270981168893993 0.404171758851919 ENG 1 GO:0008344 adult locomotory behavior 1/83 71/18722 0.270981168893993 0.404171758851919 APP 1 GO:0032722 positive regulation of chemokine production 1/83 71/18722 0.270981168893993 0.404171758851919 APP 1 GO:0043550 regulation of lipid kinase activity 1/83 71/18722 0.270981168893993 0.404171758851919 FLT1 1 GO:0045824 negative regulation of innate immune response 1/83 71/18722 0.270981168893993 0.404171758851919 ISG15 1 GO:0050818 regulation of coagulation 1/83 71/18722 0.270981168893993 0.404171758851919 SERPINE2 1 GO:0061515 myeloid cell development 1/83 71/18722 0.270981168893993 0.404171758851919 APP 1 GO:0072078 nephron tubule morphogenesis 1/83 71/18722 0.270981168893993 0.404171758851919 PBX1 1 GO:0030595 leukocyte chemotaxis 2/83 230/18722 0.271517415444934 0.40465934005787 FLT1/CSF3R 2 GO:0002696 positive regulation of leukocyte activation 3/83 409/18722 0.272225615393682 0.405402245420637 IGF2/PRKDC/EBI3 3 GO:0001707 mesoderm formation 1/83 72/18722 0.274225421908941 0.407125760791077 WLS 1 GO:0014743 regulation of muscle hypertrophy 1/83 72/18722 0.274225421908941 0.407125760791077 PARP1 1 GO:0033627 cell adhesion mediated by integrin 1/83 72/18722 0.274225421908941 0.407125760791077 ITGAV 1 GO:0043903 regulation of biological process involved in symbiotic interaction 1/83 72/18722 0.274225421908941 0.407125760791077 ITGAV 1 GO:0032271 regulation of protein polymerization 2/83 232/18722 0.274806254073674 0.407674972466932 IQGAP2/MET 2 GO:0007160 cell-matrix adhesion 2/83 233/18722 0.276450514587043 0.409405579223196 UTRN/ITGAV 2 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 2/83 233/18722 0.276450514587043 0.409405579223196 LGR5/ADGRG1 2 GO:0002637 regulation of immunoglobulin production 1/83 73/18722 0.277455410647898 0.409405579223196 PRKDC 1 GO:0032732 positive regulation of interleukin-1 production 1/83 73/18722 0.277455410647898 0.409405579223196 APP 1 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 1/83 73/18722 0.277455410647898 0.409405579223196 LRP5 1 GO:0051145 smooth muscle cell differentiation 1/83 73/18722 0.277455410647898 0.409405579223196 ENG 1 GO:0072088 nephron epithelium morphogenesis 1/83 73/18722 0.277455410647898 0.409405579223196 PBX1 1 GO:0016032 viral process 3/83 415/18722 0.279454135662002 0.411636892207209 JUN/ITGAV/ISG15 3 GO:0045930 negative regulation of mitotic cell cycle 2/83 235/18722 0.279738563361427 0.411636892207209 PRKDC/BTG1 2 GO:2000116 regulation of cysteine-type endopeptidase activity 2/83 235/18722 0.279738563361427 0.411636892207209 TNFSF10/EGLN3 2 GO:0010822 positive regulation of mitochondrion organization 1/83 74/18722 0.280671197066271 0.411636892207209 TNFSF10 1 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 1/83 74/18722 0.280671197066271 0.411636892207209 PARP1 1 GO:0048332 mesoderm morphogenesis 1/83 74/18722 0.280671197066271 0.411636892207209 WLS 1 GO:0048844 artery morphogenesis 1/83 74/18722 0.280671197066271 0.411636892207209 ENG 1 GO:0051881 regulation of mitochondrial membrane potential 1/83 74/18722 0.280671197066271 0.411636892207209 PARP1 1 GO:0016072 rRNA metabolic process 2/83 236/18722 0.281382290570899 0.412366920146739 RPS21/PRKDC 2 GO:0007409 axonogenesis 3/83 418/18722 0.283075940586077 0.414534691782491 NRP2/APP/SEMA6A 3 GO:0033077 T cell differentiation in thymus 1/83 75/18722 0.283872842853674 0.415072772493307 PRKDC 1 GO:1902369 negative regulation of RNA catabolic process 1/83 75/18722 0.283872842853674 0.415072772493307 DHX36 1 GO:0051259 protein complex oligomerization 2/83 238/18722 0.284669000006279 0.415922280432454 ALDOA/ISG15 2 GO:0050867 positive regulation of cell activation 3/83 420/18722 0.285493013122326 0.416582410989471 IGF2/PRKDC/EBI3 3 GO:0051403 stress-activated MAPK cascade 2/83 239/18722 0.286311922774028 0.416582410989471 APP/PAGE4 2 GO:1903039 positive regulation of leukocyte cell-cell adhesion 2/83 239/18722 0.286311922774028 0.416582410989471 IGF2/EBI3 2 GO:0001937 negative regulation of endothelial cell proliferation 1/83 76/18722 0.287060409435062 0.416582410989471 FLT1 1 GO:0006305 DNA alkylation 1/83 76/18722 0.287060409435062 0.416582410989471 PARP1 1 GO:0006306 DNA methylation 1/83 76/18722 0.287060409435062 0.416582410989471 PARP1 1 GO:0014823 response to activity 1/83 76/18722 0.287060409435062 0.416582410989471 PRKDC 1 GO:0021536 diencephalon development 1/83 76/18722 0.287060409435062 0.416582410989471 NRP2 1 GO:0072028 nephron morphogenesis 1/83 76/18722 0.287060409435062 0.416582410989471 PBX1 1 GO:0006816 calcium ion transport 3/83 422/18722 0.287911984303736 0.417504775438201 KCNN4/ITGAV/ATP2B1 3 GO:0002200 somatic diversification of immune receptors 1/83 77/18722 0.290233957971847 0.419441848433084 PRKDC 1 GO:0006367 transcription initiation from RNA polymerase II promoter 1/83 77/18722 0.290233957971847 0.419441848433084 DHX36 1 GO:0007492 endoderm development 1/83 77/18722 0.290233957971847 0.419441848433084 ITGAV 1 GO:0048644 muscle organ morphogenesis 1/83 77/18722 0.290233957971847 0.419441848433084 ENG 1 GO:0044772 mitotic cell cycle phase transition 3/83 424/18722 0.290332743509294 0.419441848433084 PRKDC/APP/PBX1 3 GO:1903131 mononuclear cell differentiation 3/83 426/18722 0.29275518090894 0.421657792504616 JUN/PRKDC/PBX1 3 GO:0016358 dendrite development 2/83 243/18722 0.292880052678795 0.421657792504616 APP/DHX36 2 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 1/83 78/18722 0.293393549363016 0.421657792504616 EGLN3 1 GO:0008306 associative learning 1/83 78/18722 0.293393549363016 0.421657792504616 APP 1 GO:0035050 embryonic heart tube development 1/83 78/18722 0.293393549363016 0.421657792504616 ENG 1 GO:0061045 negative regulation of wound healing 1/83 78/18722 0.293393549363016 0.421657792504616 SERPINE2 1 GO:0070373 negative regulation of ERK1 and ERK2 cascade 1/83 78/18722 0.293393549363016 0.421657792504616 SEMA6A 1 GO:0032103 positive regulation of response to external stimulus 3/83 427/18722 0.293966994826731 0.422168054234822 PRKDC/APP/MET 3 GO:0017148 negative regulation of translation 2/83 245/18722 0.29616158014624 0.424285980109538 GAPDH/DHX36 2 GO:0070663 regulation of leukocyte proliferation 2/83 245/18722 0.29616158014624 0.424285980109538 IGF2/EBI3 2 GO:0098656 anion transmembrane transport 2/83 245/18722 0.29616158014624 0.424285980109538 SLC26A2/TCAF1 2 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 1/83 79/18722 0.296539244246242 0.424285980109538 FLT1 1 GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 1/83 79/18722 0.296539244246242 0.424285980109538 GAPDH 1 GO:0003007 heart morphogenesis 2/83 246/18722 0.297801611092459 0.425462316512729 NRP2/ENG 2 GO:0031668 cellular response to extracellular stimulus 2/83 246/18722 0.297801611092459 0.425462316512729 JUN/ATP2B1 2 GO:0031098 stress-activated protein kinase signaling cascade 2/83 247/18722 0.299441116691978 0.427186019245616 APP/PAGE4 2 GO:0048145 regulation of fibroblast proliferation 1/83 80/18722 0.299671102998994 0.427186019245616 PRKDC 1 GO:0120193 tight junction organization 1/83 80/18722 0.299671102998994 0.427186019245616 SVEP1 1 GO:0033002 muscle cell proliferation 2/83 248/18722 0.301080069639028 0.428471080552504 JUN/PRKDC 2 GO:0001942 hair follicle development 1/83 81/18722 0.302789185739638 0.428471080552504 LGR5 1 GO:0001960 negative regulation of cytokine-mediated signaling pathway 1/83 81/18722 0.302789185739638 0.428471080552504 ISG15 1 GO:0008589 regulation of smoothened signaling pathway 1/83 81/18722 0.302789185739638 0.428471080552504 SERPINE2 1 GO:0021954 central nervous system neuron development 1/83 81/18722 0.302789185739638 0.428471080552504 NRP2 1 GO:0044773 mitotic DNA damage checkpoint signaling 1/83 81/18722 0.302789185739638 0.428471080552504 PRKDC 1 GO:0048144 fibroblast proliferation 1/83 81/18722 0.302789185739638 0.428471080552504 PRKDC 1 GO:0051817 modulation of process of other organism involved in symbiotic interaction 1/83 81/18722 0.302789185739638 0.428471080552504 JUN 1 GO:0071260 cellular response to mechanical stimulus 1/83 81/18722 0.302789185739638 0.428471080552504 ENG 1 GO:1903533 regulation of protein targeting 1/83 81/18722 0.302789185739638 0.428471080552504 TCAF1 1 GO:0016575 histone deacetylation 1/83 82/18722 0.305893552328534 0.431740972551783 MORF4L2 1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic 1/83 82/18722 0.305893552328534 0.431740972551783 RPS21 1 GO:2001252 positive regulation of chromosome organization 1/83 82/18722 0.305893552328534 0.431740972551783 DHX36 1 GO:0006302 double-strand break repair 2/83 251/18722 0.305993343195004 0.431740972551783 PRKDC/PARP1 2 GO:0061448 connective tissue development 2/83 252/18722 0.307629817379767 0.433417228130532 LRP5/TGFBI 2 GO:0090257 regulation of muscle system process 2/83 252/18722 0.307629817379767 0.433417228130532 ATP2B1/PARP1 2 GO:0031397 negative regulation of protein ubiquitination 1/83 83/18722 0.308984262369131 0.43382468540732 ISG15 1 GO:0046785 microtubule polymerization 1/83 83/18722 0.308984262369131 0.43382468540732 MET 1 GO:0061053 somite development 1/83 83/18722 0.308984262369131 0.43382468540732 PRKDC 1 GO:1901292 nucleoside phosphate catabolic process 1/83 83/18722 0.308984262369131 0.43382468540732 SMPDL3A 1 GO:0060828 regulation of canonical Wnt signaling pathway 2/83 253/18722 0.30926560604826 0.43382468540732 WLS/LGR5 2 GO:0097305 response to alcohol 2/83 253/18722 0.30926560604826 0.43382468540732 ATP2B1/PARP1 2 GO:0006835 dicarboxylic acid transport 1/83 84/18722 0.312061375209056 0.434592678875436 SLC26A2 1 GO:0006970 response to osmotic stress 1/83 84/18722 0.312061375209056 0.434592678875436 PAPPA2 1 GO:0022404 molting cycle process 1/83 84/18722 0.312061375209056 0.434592678875436 LGR5 1 GO:0022405 hair cycle process 1/83 84/18722 0.312061375209056 0.434592678875436 LGR5 1 GO:0032508 DNA duplex unwinding 1/83 84/18722 0.312061375209056 0.434592678875436 DHX36 1 GO:0042310 vasoconstriction 1/83 84/18722 0.312061375209056 0.434592678875436 ATP2B1 1 GO:0045445 myoblast differentiation 1/83 84/18722 0.312061375209056 0.434592678875436 BTG1 1 GO:0061157 mRNA destabilization 1/83 84/18722 0.312061375209056 0.434592678875436 DHX36 1 GO:0097061 dendritic spine organization 1/83 84/18722 0.312061375209056 0.434592678875436 DHX36 1 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 1/83 84/18722 0.312061375209056 0.434592678875436 PRKDC 1 GO:0010507 negative regulation of autophagy 1/83 85/18722 0.315124949941198 0.436344217934338 MET 1 GO:0032092 positive regulation of protein binding 1/83 85/18722 0.315124949941198 0.436344217934338 APP 1 GO:0044774 mitotic DNA integrity checkpoint signaling 1/83 85/18722 0.315124949941198 0.436344217934338 PRKDC 1 GO:0045069 regulation of viral genome replication 1/83 85/18722 0.315124949941198 0.436344217934338 ISG15 1 GO:0055072 iron ion homeostasis 1/83 85/18722 0.315124949941198 0.436344217934338 SLC40A1 1 GO:0072384 organelle transport along microtubule 1/83 85/18722 0.315124949941198 0.436344217934338 ARMCX3 1 GO:0097006 regulation of plasma lipoprotein particle levels 1/83 85/18722 0.315124949941198 0.436344217934338 LRPAP1 1 GO:0098773 skin epidermis development 1/83 85/18722 0.315124949941198 0.436344217934338 LGR5 1 GO:0042593 glucose homeostasis 2/83 258/18722 0.31743337012935 0.439225987444548 SERPINF1/LRP5 2 GO:0009798 axis specification 1/83 86/18722 0.318175045404785 0.439308830548178 WLS 1 GO:0060761 negative regulation of response to cytokine stimulus 1/83 86/18722 0.318175045404785 0.439308830548178 ISG15 1 GO:2001251 negative regulation of chromosome organization 1/83 86/18722 0.318175045404785 0.439308830548178 PARP1 1 GO:0033500 carbohydrate homeostasis 2/83 259/18722 0.319064511073093 0.439908487806198 SERPINF1/LRP5 2 GO:0045927 positive regulation of growth 2/83 259/18722 0.319064511073093 0.439908487806198 IGF2/PRKDC 2 GO:0006874 cellular calcium ion homeostasis 3/83 448/18722 0.319482142291419 0.440170335744343 APP/ITGAV/ATP2B1 3 GO:0051091 positive regulation of DNA-binding transcription factor activity 2/83 260/18722 0.320694790467504 0.440668740326784 APP/LRP5 2 GO:0019915 lipid storage 1/83 87/18722 0.321211720186466 0.440668740326784 ITGAV 1 GO:0044070 regulation of anion transport 1/83 87/18722 0.321211720186466 0.440668740326784 TCAF1 1 GO:0051262 protein tetramerization 1/83 87/18722 0.321211720186466 0.440668740326784 ALDOA 1 GO:0061014 positive regulation of mRNA catabolic process 1/83 87/18722 0.321211720186466 0.440668740326784 DHX36 1 GO:1900182 positive regulation of protein localization to nucleus 1/83 87/18722 0.321211720186466 0.440668740326784 PARP1 1 GO:0031330 negative regulation of cellular catabolic process 2/83 262/18722 0.323952667938049 0.443243506405316 MET/DHX36 2 GO:0001843 neural tube closure 1/83 88/18722 0.324235032621374 0.443243506405316 SPINT1 1 GO:0030101 natural killer cell activation 1/83 88/18722 0.324235032621374 0.443243506405316 PBX1 1 GO:0031110 regulation of microtubule polymerization or depolymerization 1/83 88/18722 0.324235032621374 0.443243506405316 MET 1 GO:0050779 RNA destabilization 1/83 88/18722 0.324235032621374 0.443243506405316 DHX36 1 GO:0043588 skin development 2/83 263/18722 0.32558021824338 0.444767888243431 LGR5/MET 2 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 2/83 264/18722 0.327206811454804 0.445782004126278 IGF2/APP 2 GO:0046330 positive regulation of JNK cascade 1/83 89/18722 0.3272450407942 0.445782004126278 APP 1 GO:0051781 positive regulation of cell division 1/83 89/18722 0.3272450407942 0.445782004126278 IGF2 1 GO:0060606 tube closure 1/83 89/18722 0.3272450407942 0.445782004126278 SPINT1 1 GO:0030901 midbrain development 1/83 90/18722 0.330241802540246 0.44734225950266 WLS 1 GO:0032392 DNA geometric change 1/83 90/18722 0.330241802540246 0.44734225950266 DHX36 1 GO:0034109 homotypic cell-cell adhesion 1/83 90/18722 0.330241802540246 0.44734225950266 SERPINE2 1 GO:0045638 negative regulation of myeloid cell differentiation 1/83 90/18722 0.330241802540246 0.44734225950266 FSTL3 1 GO:0046849 bone remodeling 1/83 90/18722 0.330241802540246 0.44734225950266 LRP5 1 GO:0048477 oogenesis 1/83 90/18722 0.330241802540246 0.44734225950266 LGR5 1 GO:0061097 regulation of protein tyrosine kinase activity 1/83 90/18722 0.330241802540246 0.44734225950266 APP 1 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 1/83 90/18722 0.330241802540246 0.44734225950266 JUN 1 GO:0001657 ureteric bud development 1/83 91/18722 0.333225375446491 0.449493824660201 PBX1 1 GO:0051492 regulation of stress fiber assembly 1/83 91/18722 0.333225375446491 0.449493824660201 MET 1 GO:0060191 regulation of lipase activity 1/83 91/18722 0.333225375446491 0.449493824660201 FLT1 1 GO:0072080 nephron tubule development 1/83 91/18722 0.333225375446491 0.449493824660201 PBX1 1 GO:0098661 inorganic anion transmembrane transport 1/83 91/18722 0.333225375446491 0.449493824660201 SLC26A2 1 GO:1990874 vascular associated smooth muscle cell proliferation 1/83 91/18722 0.333225375446491 0.449493824660201 JUN 1 GO:0055074 calcium ion homeostasis 3/83 460/18722 0.334090843531308 0.450347001775466 APP/ITGAV/ATP2B1 3 GO:0035249 synaptic transmission, glutamatergic 1/83 92/18722 0.336195816852639 0.451923862292178 SERPINE2 1 GO:0048525 negative regulation of viral process 1/83 92/18722 0.336195816852639 0.451923862292178 ISG15 1 GO:0072163 mesonephric epithelium development 1/83 92/18722 0.336195816852639 0.451923862292178 PBX1 1 GO:0072164 mesonephric tubule development 1/83 92/18722 0.336195816852639 0.451923862292178 PBX1 1 GO:0007589 body fluid secretion 1/83 93/18722 0.339153183852168 0.453063651960084 KCNN4 1 GO:0032755 positive regulation of interleukin-6 production 1/83 93/18722 0.339153183852168 0.453063651960084 APP 1 GO:0033108 mitochondrial respiratory chain complex assembly 1/83 93/18722 0.339153183852168 0.453063651960084 TFAM 1 GO:0033273 response to vitamin 1/83 93/18722 0.339153183852168 0.453063651960084 ATP2B1 1 GO:0045185 maintenance of protein location 1/83 93/18722 0.339153183852168 0.453063651960084 FBN2 1 GO:0060993 kidney morphogenesis 1/83 93/18722 0.339153183852168 0.453063651960084 PBX1 1 GO:0090398 cellular senescence 1/83 93/18722 0.339153183852168 0.453063651960084 PRKDC 1 GO:0097306 cellular response to alcohol 1/83 93/18722 0.339153183852168 0.453063651960084 ATP2B1 1 GO:1902807 negative regulation of cell cycle G1/S phase transition 1/83 93/18722 0.339153183852168 0.453063651960084 PRKDC 1 GO:0034249 negative regulation of cellular amide metabolic process 2/83 273/18722 0.341799304129694 0.454484214334087 GAPDH/DHX36 2 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 2/83 273/18722 0.341799304129694 0.454484214334087 TENM3/FXYD5 2 GO:0014020 primary neural tube formation 1/83 94/18722 0.342097533293377 0.454484214334087 SPINT1 1 GO:0019080 viral gene expression 1/83 94/18722 0.342097533293377 0.454484214334087 JUN 1 GO:0030316 osteoclast differentiation 1/83 94/18722 0.342097533293377 0.454484214334087 FSTL3 1 GO:0032091 negative regulation of protein binding 1/83 94/18722 0.342097533293377 0.454484214334087 LRPAP1 1 GO:1903035 negative regulation of response to wounding 1/83 94/18722 0.342097533293377 0.454484214334087 SERPINE2 1 GO:1990830 cellular response to leukemia inhibitory factor 1/83 94/18722 0.342097533293377 0.454484214334087 NRP2 1 GO:0033674 positive regulation of kinase activity 3/83 467/18722 0.342611258420767 0.45454190976482 IGF2/FLT1/MET 3 GO:0061564 axon development 3/83 467/18722 0.342611258420767 0.45454190976482 NRP2/APP/SEMA6A 3 GO:0008593 regulation of Notch signaling pathway 1/83 95/18722 0.34502892178042 0.455872116063946 AAK1 1 GO:0030516 regulation of axon extension 1/83 95/18722 0.34502892178042 0.455872116063946 SEMA6A 1 GO:0050764 regulation of phagocytosis 1/83 95/18722 0.34502892178042 0.455872116063946 ITGAV 1 GO:1901379 regulation of potassium ion transmembrane transport 1/83 95/18722 0.34502892178042 0.455872116063946 KCNN4 1 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 1/83 95/18722 0.34502892178042 0.455872116063946 ISG15 1 GO:1990823 response to leukemia inhibitory factor 1/83 95/18722 0.34502892178042 0.455872116063946 NRP2 1 GO:0051051 negative regulation of transport 3/83 470/18722 0.346261269041494 0.457187864110115 LRPAP1/ITGAV/SERPINE2 3 GO:1903829 positive regulation of cellular protein localization 2/83 276/18722 0.346643003135577 0.457227964084648 TCAF1/PARP1 2 GO:0001823 mesonephros development 1/83 96/18722 0.34794740567435 0.457227964084648 PBX1 1 GO:0002718 regulation of cytokine production involved in immune response 1/83 96/18722 0.34794740567435 0.457227964084648 DHX36 1 GO:0006637 acyl-CoA metabolic process 1/83 96/18722 0.34794740567435 0.457227964084648 ACSS1 1 GO:0015914 phospholipid transport 1/83 96/18722 0.34794740567435 0.457227964084648 KCNN4 1 GO:0035383 thioester metabolic process 1/83 96/18722 0.34794740567435 0.457227964084648 ACSS1 1 GO:0042632 cholesterol homeostasis 1/83 96/18722 0.34794740567435 0.457227964084648 LRP5 1 GO:0110053 regulation of actin filament organization 2/83 277/18722 0.34825511009946 0.457321418357511 IQGAP2/MET 2 GO:0031349 positive regulation of defense response 2/83 278/18722 0.349865952919059 0.458862603812567 PRKDC/APP 2 GO:0010596 negative regulation of endothelial cell migration 1/83 97/18722 0.350853041094141 0.458862603812567 SERPINF1 1 GO:0043255 regulation of carbohydrate biosynthetic process 1/83 97/18722 0.350853041094141 0.458862603812567 IGF2 1 GO:0055092 sterol homeostasis 1/83 97/18722 0.350853041094141 0.458862603812567 LRP5 1 GO:0120162 positive regulation of cold-induced thermogenesis 1/83 97/18722 0.350853041094141 0.458862603812567 PLAC8 1 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 1/83 97/18722 0.350853041094141 0.458862603812567 ITGAV 1 GO:0002367 cytokine production involved in immune response 1/83 98/18722 0.353745883917722 0.461086172362074 DHX36 1 GO:0032642 regulation of chemokine production 1/83 98/18722 0.353745883917722 0.461086172362074 APP 1 GO:0043502 regulation of muscle adaptation 1/83 98/18722 0.353745883917722 0.461086172362074 PARP1 1 GO:0061337 cardiac conduction 1/83 98/18722 0.353745883917722 0.461086172362074 ATP2B1 1 GO:0070301 cellular response to hydrogen peroxide 1/83 98/18722 0.353745883917722 0.461086172362074 MET 1 GO:0002444 myeloid leukocyte mediated immunity 1/83 99/18722 0.356625989782994 0.461417696285493 DHX36 1 GO:0003300 cardiac muscle hypertrophy 1/83 99/18722 0.356625989782994 0.461417696285493 PARP1 1 GO:0007631 feeding behavior 1/83 99/18722 0.356625989782994 0.461417696285493 APP 1 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 1/83 99/18722 0.356625989782994 0.461417696285493 PRKDC 1 GO:0010717 regulation of epithelial to mesenchymal transition 1/83 99/18722 0.356625989782994 0.461417696285493 ENG 1 GO:0021549 cerebellum development 1/83 99/18722 0.356625989782994 0.461417696285493 SERPINE2 1 GO:0030838 positive regulation of actin filament polymerization 1/83 99/18722 0.356625989782994 0.461417696285493 IQGAP2 1 GO:0032602 chemokine production 1/83 99/18722 0.356625989782994 0.461417696285493 APP 1 GO:0033209 tumor necrosis factor-mediated signaling pathway 1/83 99/18722 0.356625989782994 0.461417696285493 KRT8 1 GO:0051153 regulation of striated muscle cell differentiation 1/83 99/18722 0.356625989782994 0.461417696285493 MORF4L2 1 GO:0060996 dendritic spine development 1/83 99/18722 0.356625989782994 0.461417696285493 DHX36 1 GO:0044262 cellular carbohydrate metabolic process 2/83 283/18722 0.357900498864696 0.462756966090607 IGF2/AGL 2 GO:0043410 positive regulation of MAPK cascade 3/83 480/18722 0.358416127974711 0.462958540595438 IGF2/FLT1/APP 3 GO:0044728 DNA methylation or demethylation 1/83 100/18722 0.359493414088853 0.462958540595438 PARP1 1 GO:0060079 excitatory postsynaptic potential 1/83 100/18722 0.359493414088853 0.462958540595438 APP 1 GO:0060840 artery development 1/83 100/18722 0.359493414088853 0.462958540595438 ENG 1 GO:0061640 cytoskeleton-dependent cytokinesis 1/83 100/18722 0.359493414088853 0.462958540595438 MYH10 1 GO:0110020 regulation of actomyosin structure organization 1/83 100/18722 0.359493414088853 0.462958540595438 MET 1 GO:0048562 embryonic organ morphogenesis 2/83 285/18722 0.361104770577886 0.464724048952765 FBN2/ENG 2 GO:0006476 protein deacetylation 1/83 101/18722 0.3623482119962 0.465704184699903 MORF4L2 1 GO:0051963 regulation of synapse assembly 1/83 101/18722 0.3623482119962 0.465704184699903 APP 1 GO:0140014 mitotic nuclear division 2/83 287/18722 0.364303356222639 0.467781486960691 IGF2/LRP5 2 GO:0001841 neural tube formation 1/83 102/18722 0.365190438428954 0.467781486960691 SPINT1 1 GO:0014897 striated muscle hypertrophy 1/83 102/18722 0.365190438428954 0.467781486960691 PARP1 1 GO:0062014 negative regulation of small molecule metabolic process 1/83 102/18722 0.365190438428954 0.467781486960691 PARP1 1 GO:1902106 negative regulation of leukocyte differentiation 1/83 102/18722 0.365190438428954 0.467781486960691 FSTL3 1 GO:0072503 cellular divalent inorganic cation homeostasis 3/83 486/18722 0.365696942017102 0.467781486960691 APP/ITGAV/ATP2B1 3 GO:0046651 lymphocyte proliferation 2/83 288/18722 0.365900469883375 0.467781486960691 IGF2/EBI3 2 GO:0097193 intrinsic apoptotic signaling pathway 2/83 288/18722 0.365900469883375 0.467781486960691 PRKDC/PARP1 2 GO:0042110 T cell activation 3/83 487/18722 0.366909314805459 0.468761206555817 IGF2/PRKDC/EBI3 3 GO:0030593 neutrophil chemotaxis 1/83 103/18722 0.368020148075055 0.469249964531056 CSF3R 1 GO:0032760 positive regulation of tumor necrosis factor production 1/83 103/18722 0.368020148075055 0.469249964531056 APP 1 GO:0050773 regulation of dendrite development 1/83 103/18722 0.368020148075055 0.469249964531056 DHX36 1 GO:0032943 mononuclear cell proliferation 2/83 291/18722 0.370682873708686 0.470668867553494 IGF2/EBI3 2 GO:0014896 muscle hypertrophy 1/83 104/18722 0.370837395387466 0.470668867553494 PARP1 1 GO:0022600 digestive system process 1/83 104/18722 0.370837395387466 0.470668867553494 KCNN4 1 GO:0032963 collagen metabolic process 1/83 104/18722 0.370837395387466 0.470668867553494 ENG 1 GO:0045621 positive regulation of lymphocyte differentiation 1/83 104/18722 0.370837395387466 0.470668867553494 PRKDC 1 GO:0046634 regulation of alpha-beta T cell activation 1/83 104/18722 0.370837395387466 0.470668867553494 EBI3 1 GO:0048661 positive regulation of smooth muscle cell proliferation 1/83 104/18722 0.370837395387466 0.470668867553494 JUN 1 GO:0000041 transition metal ion transport 1/83 105/18722 0.373642234585169 0.473296487190781 SLC40A1 1 GO:0032231 regulation of actin filament bundle assembly 1/83 105/18722 0.373642234585169 0.473296487190781 MET 1 GO:0040029 regulation of gene expression, epigenetic 1/83 105/18722 0.373642234585169 0.473296487190781 IGF2 1 GO:0051604 protein maturation 2/83 294/18722 0.375451494716285 0.473729370502275 SERPINE2/PARP1 2 GO:0002062 chondrocyte differentiation 1/83 106/18722 0.376434719654161 0.473729370502275 TGFBI 1 GO:0006766 vitamin metabolic process 1/83 106/18722 0.376434719654161 0.473729370502275 CYP11A1 1 GO:0019882 antigen processing and presentation 1/83 106/18722 0.376434719654161 0.473729370502275 HLA-C 1 GO:0035821 modulation of process of other organism 1/83 106/18722 0.376434719654161 0.473729370502275 JUN 1 GO:0042116 macrophage activation 1/83 106/18722 0.376434719654161 0.473729370502275 APP 1 GO:0046620 regulation of organ growth 1/83 106/18722 0.376434719654161 0.473729370502275 IGF2 1 GO:0099565 chemical synaptic transmission, postsynaptic 1/83 106/18722 0.376434719654161 0.473729370502275 APP 1 GO:1903707 negative regulation of hemopoiesis 1/83 106/18722 0.376434719654161 0.473729370502275 FSTL3 1 GO:1905477 positive regulation of protein localization to membrane 1/83 106/18722 0.376434719654161 0.473729370502275 TCAF1 1 GO:0051258 protein polymerization 2/83 296/18722 0.378622684361006 0.473834783520062 IQGAP2/MET 2 GO:0000018 regulation of DNA recombination 1/83 107/18722 0.379214904348441 0.473834783520062 PARP1 1 GO:0006275 regulation of DNA replication 1/83 107/18722 0.379214904348441 0.473834783520062 JUN 1 GO:0021761 limbic system development 1/83 107/18722 0.379214904348441 0.473834783520062 NRP2 1 GO:0031532 actin cytoskeleton reorganization 1/83 107/18722 0.379214904348441 0.473834783520062 IQGAP2 1 GO:0032526 response to retinoic acid 1/83 107/18722 0.379214904348441 0.473834783520062 SERPINF1 1 GO:0042303 molting cycle 1/83 107/18722 0.379214904348441 0.473834783520062 LGR5 1 GO:0042633 hair cycle 1/83 107/18722 0.379214904348441 0.473834783520062 LGR5 1 GO:0071868 cellular response to monoamine stimulus 1/83 107/18722 0.379214904348441 0.473834783520062 APP 1 GO:0071870 cellular response to catecholamine stimulus 1/83 107/18722 0.379214904348441 0.473834783520062 APP 1 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 1/83 107/18722 0.379214904348441 0.473834783520062 APP 1 GO:0022037 metencephalon development 1/83 108/18722 0.381982842190991 0.476062433239965 SERPINE2 1 GO:0033138 positive regulation of peptidyl-serine phosphorylation 1/83 108/18722 0.381982842190991 0.476062433239965 APP 1 GO:0034446 substrate adhesion-dependent cell spreading 1/83 108/18722 0.381982842190991 0.476062433239965 ITGAV 1 GO:0140053 mitochondrial gene expression 1/83 108/18722 0.381982842190991 0.476062433239965 TFAM 1 GO:0042254 ribosome biogenesis 2/83 299/18722 0.383367291369197 0.477480009160218 RPS21/PRKDC 2 GO:0032414 positive regulation of ion transmembrane transporter activity 1/83 109/18722 0.384738586474764 0.478263464730366 TCAF1 1 GO:0043266 regulation of potassium ion transport 1/83 109/18722 0.384738586474764 0.478263464730366 KCNN4 1 GO:0072009 nephron epithelium development 1/83 109/18722 0.384738586474764 0.478263464730366 PBX1 1 GO:0002698 negative regulation of immune effector process 1/83 110/18722 0.387482190263653 0.479822596912006 PRKDC 1 GO:0006939 smooth muscle contraction 1/83 110/18722 0.387482190263653 0.479822596912006 ATP2B1 1 GO:0009408 response to heat 1/83 110/18722 0.387482190263653 0.479822596912006 DHX36 1 GO:0032611 interleukin-1 beta production 1/83 110/18722 0.387482190263653 0.479822596912006 APP 1 GO:0032651 regulation of interleukin-1 beta production 1/83 110/18722 0.387482190263653 0.479822596912006 APP 1 GO:0061387 regulation of extent of cell growth 1/83 110/18722 0.387482190263653 0.479822596912006 SEMA6A 1 GO:0071867 response to monoamine 1/83 111/18722 0.390213706393468 0.482586752692626 APP 1 GO:0071869 response to catecholamine 1/83 111/18722 0.390213706393468 0.482586752692626 APP 1 GO:0006310 DNA recombination 2/83 305/18722 0.392811040181308 0.484091683483187 PRKDC/PARP1 2 GO:0000956 nuclear-transcribed mRNA catabolic process 1/83 112/18722 0.392933187472902 0.484091683483187 DHX36 1 GO:0010633 negative regulation of epithelial cell migration 1/83 112/18722 0.392933187472902 0.484091683483187 SERPINF1 1 GO:0035601 protein deacylation 1/83 112/18722 0.392933187472902 0.484091683483187 MORF4L2 1 GO:0043406 positive regulation of MAP kinase activity 1/83 112/18722 0.392933187472902 0.484091683483187 FLT1 1 GO:1901222 regulation of NIK/NF-kappaB signaling 1/83 112/18722 0.392933187472902 0.484091683483187 APP 1 GO:0031623 receptor internalization 1/83 113/18722 0.395640685884495 0.487116844467981 LRPAP1 1 GO:0002440 production of molecular mediator of immune response 2/83 308/18722 0.397509327495798 0.488794866443625 PRKDC/DHX36 2 GO:0006909 phagocytosis 2/83 308/18722 0.397509327495798 0.488794866443625 ITGAV/MET 2 GO:0021987 cerebral cortex development 1/83 114/18722 0.398336253785596 0.489500304238752 ADGRG1 1 GO:0070372 regulation of ERK1 and ERK2 cascade 2/83 309/18722 0.399071827053211 0.490092656730531 APP/SEMA6A 2 GO:0000077 DNA damage checkpoint signaling 1/83 115/18722 0.401019943109317 0.491860120577608 PRKDC 1 GO:0071675 regulation of mononuclear cell migration 1/83 115/18722 0.401019943109317 0.491860120577608 APP 1 GO:0008286 insulin receptor signaling pathway 1/83 116/18722 0.403691805565485 0.493640432236024 IGF2 1 GO:0021782 glial cell development 1/83 116/18722 0.403691805565485 0.493640432236024 APP 1 GO:0030518 intracellular steroid hormone receptor signaling pathway 1/83 116/18722 0.403691805565485 0.493640432236024 PARP1 1 GO:0098732 macromolecule deacylation 1/83 116/18722 0.403691805565485 0.493640432236024 MORF4L2 1 GO:0070588 calcium ion transmembrane transport 2/83 312/18722 0.403748330763142 0.493640432236024 ITGAV/ATP2B1 2 GO:0002702 positive regulation of production of molecular mediator of immune response 1/83 117/18722 0.406351892641593 0.496195962398105 DHX36 1 GO:0072676 lymphocyte migration 1/83 117/18722 0.406351892641593 0.496195962398105 APP 1 GO:0060249 anatomical structure homeostasis 2/83 314/18722 0.406856693706942 0.496498730388586 ALDOA/ATP2B1 2 GO:0018105 peptidyl-serine phosphorylation 2/83 315/18722 0.408408041040268 0.4975440491391 PRKDC/APP 2 GO:0007613 memory 1/83 118/18722 0.40900025560374 0.4975440491391 SERPINF1 1 GO:0022612 gland morphogenesis 1/83 118/18722 0.40900025560374 0.4975440491391 LRP5 1 GO:0071346 cellular response to interferon-gamma 1/83 118/18722 0.40900025560374 0.4975440491391 GAPDH 1 GO:1903313 positive regulation of mRNA metabolic process 1/83 118/18722 0.40900025560374 0.4975440491391 DHX36 1 GO:0043414 macromolecule methylation 2/83 316/18722 0.409957480525456 0.498394848965854 BTG1/PARP1 2 GO:0006959 humoral immune response 2/83 317/18722 0.411504998540956 0.49918081282736 EBI3/GAPDH 2 GO:0010506 regulation of autophagy 2/83 317/18722 0.411504998540956 0.49918081282736 GAPDH/MET 2 GO:0019058 viral life cycle 2/83 317/18722 0.411504998540956 0.49918081282736 ITGAV/ISG15 2 GO:0010906 regulation of glucose metabolic process 1/83 119/18722 0.411636945497575 0.49918081282736 IGF2 1 GO:0015980 energy derivation by oxidation of organic compounds 2/83 318/18722 0.413050581620123 0.500267402425876 IGF2/AGL 2 GO:0070661 leukocyte proliferation 2/83 318/18722 0.413050581620123 0.500267402425876 IGF2/EBI3 2 GO:0006304 DNA modification 1/83 120/18722 0.414262013149228 0.500793290442437 PARP1 1 GO:0032411 positive regulation of transporter activity 1/83 120/18722 0.414262013149228 0.500793290442437 TCAF1 1 GO:0071901 negative regulation of protein serine/threonine kinase activity 1/83 120/18722 0.414262013149228 0.500793290442437 LRP5 1 GO:0001838 embryonic epithelial tube formation 1/83 121/18722 0.416875509166248 0.502068759637606 SPINT1 1 GO:0042177 negative regulation of protein catabolic process 1/83 121/18722 0.416875509166248 0.502068759637606 SERPINE2 1 GO:0042752 regulation of circadian rhythm 1/83 121/18722 0.416875509166248 0.502068759637606 PRKDC 1 GO:0043500 muscle adaptation 1/83 121/18722 0.416875509166248 0.502068759637606 PARP1 1 GO:0048706 embryonic skeletal system development 1/83 121/18722 0.416875509166248 0.502068759637606 PBX1 1 GO:1904019 epithelial cell apoptotic process 1/83 121/18722 0.416875509166248 0.502068759637606 KRT8 1 GO:0019730 antimicrobial humoral response 1/83 122/18722 0.419477483938529 0.503946536018134 GAPDH 1 GO:0031109 microtubule polymerization or depolymerization 1/83 122/18722 0.419477483938529 0.503946536018134 MET 1 GO:0051928 positive regulation of calcium ion transport 1/83 122/18722 0.419477483938529 0.503946536018134 ATP2B1 1 GO:1990266 neutrophil migration 1/83 122/18722 0.419477483938529 0.503946536018134 CSF3R 1 GO:0003231 cardiac ventricle development 1/83 123/18722 0.422067987639233 0.505431877042971 ENG 1 GO:0010811 positive regulation of cell-substrate adhesion 1/83 123/18722 0.422067987639233 0.505431877042971 UTRN 1 GO:0030168 platelet activation 1/83 123/18722 0.422067987639233 0.505431877042971 SERPINE2 1 GO:0031570 DNA integrity checkpoint signaling 1/83 123/18722 0.422067987639233 0.505431877042971 PRKDC 1 GO:0050852 T cell receptor signaling pathway 1/83 123/18722 0.422067987639233 0.505431877042971 KCNN4 1 GO:0008544 epidermis development 2/83 324/18722 0.422282711549094 0.505431877042971 SVEP1/LGR5 2 GO:0007368 determination of left/right symmetry 1/83 124/18722 0.424647070225714 0.507947269026178 ENG 1 GO:0051235 maintenance of location 2/83 326/18722 0.425344022822587 0.508466293207211 FBN2/ITGAV 2 GO:0051053 negative regulation of DNA metabolic process 1/83 125/18722 0.427214781440428 0.509756896619968 PARP1 1 GO:0070585 protein localization to mitochondrion 1/83 125/18722 0.427214781440428 0.509756896619968 ISG15 1 GO:0071621 granulocyte chemotaxis 1/83 125/18722 0.427214781440428 0.509756896619968 CSF3R 1 GO:0032874 positive regulation of stress-activated MAPK cascade 1/83 126/18722 0.429771170811856 0.512037277056007 APP 1 GO:2001235 positive regulation of apoptotic signaling pathway 1/83 126/18722 0.429771170811856 0.512037277056007 TNFSF10 1 GO:0050863 regulation of T cell activation 2/83 329/18722 0.429920590099276 0.512037277056007 IGF2/EBI3 2 GO:0030048 actin filament-based movement 1/83 127/18722 0.432316287655404 0.514573512338606 MYH10 1 GO:0001952 regulation of cell-matrix adhesion 1/83 128/18722 0.434850181074313 0.516317813278038 UTRN 1 GO:0032612 interleukin-1 production 1/83 128/18722 0.434850181074313 0.516317813278038 APP 1 GO:0032652 regulation of interleukin-1 production 1/83 128/18722 0.434850181074313 0.516317813278038 APP 1 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 1/83 128/18722 0.434850181074313 0.516317813278038 APP 1 GO:0007093 mitotic cell cycle checkpoint signaling 1/83 129/18722 0.437372899960557 0.518675960505372 PRKDC 1 GO:0007498 mesoderm development 1/83 129/18722 0.437372899960557 0.518675960505372 WLS 1 GO:0030534 adult behavior 1/83 130/18722 0.439884492995747 0.521334595316234 APP 1 GO:1903037 regulation of leukocyte cell-cell adhesion 2/83 336/18722 0.440525750233151 0.52177467843179 IGF2/EBI3 2 GO:0006612 protein targeting to membrane 1/83 131/18722 0.442385008652015 0.523015426131098 TCAF1 1 GO:0019079 viral genome replication 1/83 131/18722 0.442385008652015 0.523015426131098 ISG15 1 GO:0045089 positive regulation of innate immune response 1/83 131/18722 0.442385008652015 0.523015426131098 PRKDC 1 GO:0007569 cell aging 1/83 132/18722 0.444874495192916 0.525189015386423 PRKDC 1 GO:0072175 epithelial tube formation 1/83 132/18722 0.444874495192916 0.525189015386423 SPINT1 1 GO:0002697 regulation of immune effector process 2/83 339/18722 0.44503859658715 0.525189015386423 PRKDC/DHX36 2 GO:0009855 determination of bilateral symmetry 1/83 133/18722 0.447353000674303 0.527276433111846 ENG 1 GO:0046328 regulation of JNK cascade 1/83 133/18722 0.447353000674303 0.527276433111846 APP 1 GO:0002705 positive regulation of leukocyte mediated immunity 1/83 134/18722 0.449820572945218 0.528894870743982 DHX36 1 GO:0008277 regulation of G protein-coupled receptor signaling pathway 1/83 134/18722 0.449820572945218 0.528894870743982 MET 1 GO:0009799 specification of symmetry 1/83 134/18722 0.449820572945218 0.528894870743982 ENG 1 GO:0061041 regulation of wound healing 1/83 134/18722 0.449820572945218 0.528894870743982 SERPINE2 1 GO:0001101 response to acid chemical 1/83 135/18722 0.452277259648766 0.53049268379919 KRT8 1 GO:0002687 positive regulation of leukocyte migration 1/83 135/18722 0.452277259648766 0.53049268379919 APP 1 GO:0009581 detection of external stimulus 1/83 135/18722 0.452277259648766 0.53049268379919 SERPINE2 1 GO:0042157 lipoprotein metabolic process 1/83 135/18722 0.452277259648766 0.53049268379919 ITGAV 1 GO:0043401 steroid hormone mediated signaling pathway 1/83 136/18722 0.454723108222993 0.532392348997604 PARP1 1 GO:0072073 kidney epithelium development 1/83 136/18722 0.454723108222993 0.532392348997604 PBX1 1 GO:1900180 regulation of protein localization to nucleus 1/83 136/18722 0.454723108222993 0.532392348997604 PARP1 1 GO:0010639 negative regulation of organelle organization 2/83 347/18722 0.456975583146392 0.532983555300419 PARP1/MET 2 GO:0007586 digestion 1/83 137/18722 0.457158165901756 0.532983555300419 KCNN4 1 GO:0010977 negative regulation of neuron projection development 1/83 137/18722 0.457158165901756 0.532983555300419 SEMA6A 1 GO:0030879 mammary gland development 1/83 137/18722 0.457158165901756 0.532983555300419 LRP5 1 GO:0034754 cellular hormone metabolic process 1/83 137/18722 0.457158165901756 0.532983555300419 CYP11A1 1 GO:0050684 regulation of mRNA processing 1/83 137/18722 0.457158165901756 0.532983555300419 DHX36 1 GO:0060078 regulation of postsynaptic membrane potential 1/83 137/18722 0.457158165901756 0.532983555300419 APP 1 GO:0043087 regulation of GTPase activity 2/83 348/18722 0.458457581940344 0.534176314581486 IQGAP2/MET 2 GO:0000724 double-strand break repair via homologous recombination 1/83 138/18722 0.459582479715592 0.534520417142142 PARP1 1 GO:0007224 smoothened signaling pathway 1/83 138/18722 0.459582479715592 0.534520417142142 SERPINE2 1 GO:0009582 detection of abiotic stimulus 1/83 138/18722 0.459582479715592 0.534520417142142 SERPINE2 1 GO:0000725 recombinational repair 1/83 140/18722 0.464399062859215 0.539149182286404 PARP1 1 GO:0007292 female gamete generation 1/83 140/18722 0.464399062859215 0.539149182286404 LGR5 1 GO:0015748 organophosphate ester transport 1/83 140/18722 0.464399062859215 0.539149182286404 KCNN4 1 GO:0051480 regulation of cytosolic calcium ion concentration 2/83 353/18722 0.465833179062099 0.539657790066571 ITGAV/ATP2B1 2 GO:0016241 regulation of macroautophagy 1/83 141/18722 0.466791425241235 0.539657790066571 GAPDH 1 GO:0030183 B cell differentiation 1/83 141/18722 0.466791425241235 0.539657790066571 PRKDC 1 GO:0034341 response to interferon-gamma 1/83 141/18722 0.466791425241235 0.539657790066571 GAPDH 1 GO:0035296 regulation of tube diameter 1/83 141/18722 0.466791425241235 0.539657790066571 ATP2B1 1 GO:0050921 positive regulation of chemotaxis 1/83 141/18722 0.466791425241235 0.539657790066571 MET 1 GO:0097746 blood vessel diameter maintenance 1/83 141/18722 0.466791425241235 0.539657790066571 ATP2B1 1 GO:0035150 regulation of tube size 1/83 142/18722 0.469173229864504 0.541116857594324 ATP2B1 1 GO:0050729 positive regulation of inflammatory response 1/83 142/18722 0.469173229864504 0.541116857594324 APP 1 GO:0072006 nephron development 1/83 142/18722 0.469173229864504 0.541116857594324 PBX1 1 GO:2000045 regulation of G1/S transition of mitotic cell cycle 1/83 142/18722 0.469173229864504 0.541116857594324 PRKDC 1 GO:0038061 NIK/NF-kappaB signaling 1/83 143/18722 0.471544522755852 0.543049649375033 APP 1 GO:0070555 response to interleukin-1 1/83 143/18722 0.471544522755852 0.543049649375033 APP 1 GO:0032956 regulation of actin cytoskeleton organization 2/83 357/18722 0.471691857889643 0.543049649375033 IQGAP2/MET 2 GO:0010821 regulation of mitochondrion organization 1/83 144/18722 0.473905349743918 0.543655217243319 TNFSF10 1 GO:0031644 regulation of nervous system process 1/83 144/18722 0.473905349743918 0.543655217243319 APP 1 GO:0033135 regulation of peptidyl-serine phosphorylation 1/83 144/18722 0.473905349743918 0.543655217243319 APP 1 GO:0046718 viral entry into host cell 1/83 144/18722 0.473905349743918 0.543655217243319 ITGAV 1 GO:0106106 cold-induced thermogenesis 1/83 144/18722 0.473905349743918 0.543655217243319 PLAC8 1 GO:0120161 regulation of cold-induced thermogenesis 1/83 144/18722 0.473905349743918 0.543655217243319 PLAC8 1 GO:0010675 regulation of cellular carbohydrate metabolic process 1/83 146/18722 0.478595788338866 0.548385097130426 IGF2 1 GO:0048813 dendrite morphogenesis 1/83 146/18722 0.478595788338866 0.548385097130426 DHX36 1 GO:0031589 cell-substrate adhesion 2/83 363/18722 0.480408975845994 0.550076315602241 UTRN/ITGAV 2 GO:0001889 liver development 1/83 147/18722 0.480925490619652 0.550076315602241 MET 1 GO:0016331 morphogenesis of embryonic epithelium 1/83 147/18722 0.480925490619652 0.550076315602241 SPINT1 1 GO:0032259 methylation 2/83 364/18722 0.481853457371093 0.550773825373839 BTG1/PARP1 2 GO:0035148 tube formation 1/83 148/18722 0.483244908346627 0.550773825373839 SPINT1 1 GO:0050905 neuromuscular process 1/83 148/18722 0.483244908346627 0.550773825373839 APP 1 GO:0070507 regulation of microtubule cytoskeleton organization 1/83 148/18722 0.483244908346627 0.550773825373839 MET 1 GO:0097530 granulocyte migration 1/83 148/18722 0.483244908346627 0.550773825373839 CSF3R 1 GO:1903900 regulation of viral life cycle 1/83 148/18722 0.483244908346627 0.550773825373839 ISG15 1 GO:0032368 regulation of lipid transport 1/83 149/18722 0.485554086370059 0.552753856862971 ITGAV 1 GO:0045834 positive regulation of lipid metabolic process 1/83 149/18722 0.485554086370059 0.552753856862971 FLT1 1 GO:0001959 regulation of cytokine-mediated signaling pathway 1/83 150/18722 0.487853069347031 0.554717637086947 ISG15 1 GO:0061008 hepaticobiliary system development 1/83 150/18722 0.487853069347031 0.554717637086947 MET 1 GO:0044409 entry into host 1/83 151/18722 0.49014190174226 0.556338400509565 ITGAV 1 GO:0071456 cellular response to hypoxia 1/83 151/18722 0.49014190174226 0.556338400509565 EGLN3 1 GO:1904064 positive regulation of cation transmembrane transport 1/83 151/18722 0.49014190174226 0.556338400509565 KCNN4 1 GO:0007159 leukocyte cell-cell adhesion 2/83 371/18722 0.491896906230832 0.556962594261735 IGF2/EBI3 2 GO:0016573 histone acetylation 1/83 152/18722 0.492420627828921 0.556962594261735 MORF4L2 1 GO:0021915 neural tube development 1/83 152/18722 0.492420627828921 0.556962594261735 SPINT1 1 GO:0031056 regulation of histone modification 1/83 152/18722 0.492420627828921 0.556962594261735 IGF2 1 GO:0051092 positive regulation of NF-kappaB transcription factor activity 1/83 152/18722 0.492420627828921 0.556962594261735 APP 1 GO:0090501 RNA phosphodiester bond hydrolysis 1/83 152/18722 0.492420627828921 0.556962594261735 RPS21 1 GO:0120254 olefinic compound metabolic process 1/83 153/18722 0.49468929168946 0.559201403997501 CYP11A1 1 GO:0030098 lymphocyte differentiation 2/83 374/18722 0.496164480202048 0.560541169041822 PRKDC/PBX1 2 GO:0030856 regulation of epithelial cell differentiation 1/83 154/18722 0.496947937216401 0.560770789631818 BTG1 1 GO:0050770 regulation of axonogenesis 1/83 154/18722 0.496947937216401 0.560770789631818 SEMA6A 1 GO:0002253 activation of immune response 2/83 375/18722 0.497582055737911 0.561158759475719 PRKDC/KCNN4 2 GO:0007519 skeletal muscle tissue development 1/83 155/18722 0.499196608113161 0.562323451913019 IGF2 1 GO:0046434 organophosphate catabolic process 1/83 155/18722 0.499196608113161 0.562323451913019 SMPDL3A 1 GO:0009267 cellular response to starvation 1/83 156/18722 0.50143534789485 0.563859527330276 JUN 1 GO:0035051 cardiocyte differentiation 1/83 156/18722 0.50143534789485 0.563859527330276 DHX36 1 GO:0046631 alpha-beta T cell activation 1/83 156/18722 0.50143534789485 0.563859527330276 EBI3 1 GO:0001837 epithelial to mesenchymal transition 1/83 157/18722 0.503664199889072 0.565379151211136 ENG 1 GO:1990845 adaptive thermogenesis 1/83 157/18722 0.503664199889072 0.565379151211136 PLAC8 1 GO:2000377 regulation of reactive oxygen species metabolic process 1/83 157/18722 0.503664199889072 0.565379151211136 PAGE4 1 GO:0018393 internal peptidyl-lysine acetylation 1/83 158/18722 0.505883207236727 0.567211275863453 MORF4L2 1 GO:0043488 regulation of mRNA stability 1/83 158/18722 0.505883207236727 0.567211275863453 DHX36 1 GO:0007018 microtubule-based movement 2/83 382/18722 0.507435177497839 0.568621564117868 ARMCX3/APP 2 GO:0014706 striated muscle tissue development 2/83 384/18722 0.510227713782794 0.570170037375317 IGF2/ENG 2 GO:0006475 internal protein amino acid acetylation 1/83 160/18722 0.510291859627159 0.570170037375317 MORF4L2 1 GO:0035637 multicellular organismal signaling 1/83 160/18722 0.510291859627159 0.570170037375317 ATP2B1 1 GO:0043271 negative regulation of ion transport 1/83 160/18722 0.510291859627159 0.570170037375317 SERPINE2 1 GO:0090316 positive regulation of intracellular protein transport 1/83 160/18722 0.510291859627159 0.570170037375317 TCAF1 1 GO:0045786 negative regulation of cell cycle 2/83 385/18722 0.511620181162624 0.571323980466408 PRKDC/BTG1 2 GO:0036294 cellular response to decreased oxygen levels 1/83 161/18722 0.512481590025335 0.571884970226544 EGLN3 1 GO:0045860 positive regulation of protein kinase activity 2/83 386/18722 0.513010107797635 0.571884970226544 IGF2/FLT1 2 GO:0050727 regulation of inflammatory response 2/83 386/18722 0.513010107797635 0.571884970226544 APP/SERPINF1 2 GO:0021953 central nervous system neuron differentiation 1/83 162/18722 0.514661646489313 0.572735154095476 NRP2 1 GO:0051494 negative regulation of cytoskeleton organization 1/83 162/18722 0.514661646489313 0.572735154095476 MET 1 GO:0060759 regulation of response to cytokine stimulus 1/83 162/18722 0.514661646489313 0.572735154095476 ISG15 1 GO:0006633 fatty acid biosynthetic process 1/83 163/18722 0.51683207123831 0.574819559093011 ACSS1 1 GO:0050792 regulation of viral process 1/83 164/18722 0.518992906309554 0.576559360859981 ISG15 1 GO:2001242 regulation of intrinsic apoptotic signaling pathway 1/83 164/18722 0.518992906309554 0.576559360859981 PARP1 1 GO:0032635 interleukin-6 production 1/83 165/18722 0.521144193559059 0.577952797561481 APP 1 GO:0032675 regulation of interleukin-6 production 1/83 165/18722 0.521144193559059 0.577952797561481 APP 1 GO:0050796 regulation of insulin secretion 1/83 165/18722 0.521144193559059 0.577952797561481 LRP5 1 GO:0043112 receptor metabolic process 1/83 166/18722 0.523285974662394 0.578999306824504 LRPAP1 1 GO:0060538 skeletal muscle organ development 1/83 166/18722 0.523285974662394 0.578999306824504 IGF2 1 GO:0061013 regulation of mRNA catabolic process 1/83 166/18722 0.523285974662394 0.578999306824504 DHX36 1 GO:1902904 negative regulation of supramolecular fiber organization 1/83 166/18722 0.523285974662394 0.578999306824504 MET 1 GO:0034470 ncRNA processing 2/83 395/18722 0.525404309533622 0.579699518679325 RPS21/PRKDC 2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 1/83 167/18722 0.525418291115456 0.579699518679325 TENM3 1 GO:0007254 JNK cascade 1/83 167/18722 0.525418291115456 0.579699518679325 APP 1 GO:0055088 lipid homeostasis 1/83 167/18722 0.525418291115456 0.579699518679325 LRP5 1 GO:1903034 regulation of response to wounding 1/83 167/18722 0.525418291115456 0.579699518679325 SERPINE2 1 GO:0032970 regulation of actin filament-based process 2/83 396/18722 0.52676856556514 0.580715893580126 IQGAP2/MET 2 GO:0002833 positive regulation of response to biotic stimulus 1/83 168/18722 0.527541184235231 0.580715893580126 PRKDC 1 GO:1902806 regulation of cell cycle G1/S phase transition 1/83 168/18722 0.527541184235231 0.580715893580126 PRKDC 1 GO:2000241 regulation of reproductive process 1/83 168/18722 0.527541184235231 0.580715893580126 SERPINF1 1 GO:0006869 lipid transport 2/83 398/18722 0.529489299366214 0.581387010644721 KCNN4/ITGAV 2 GO:0000075 cell cycle checkpoint signaling 1/83 169/18722 0.529654695160556 0.581387010644721 PRKDC 1 GO:0006937 regulation of muscle contraction 1/83 169/18722 0.529654695160556 0.581387010644721 ATP2B1 1 GO:0018394 peptidyl-lysine acetylation 1/83 169/18722 0.529654695160556 0.581387010644721 MORF4L2 1 GO:0021543 pallium development 1/83 169/18722 0.529654695160556 0.581387010644721 ADGRG1 1 GO:0043487 regulation of RNA stability 1/83 170/18722 0.531758864852879 0.583365428922029 DHX36 1 GO:0030833 regulation of actin filament polymerization 1/83 171/18722 0.533853734097015 0.584999585039416 IQGAP2 1 GO:0048469 cell maturation 1/83 171/18722 0.533853734097015 0.584999585039416 APP 1 GO:0042770 signal transduction in response to DNA damage 1/83 172/18722 0.535939343501896 0.586952266849385 PRKDC 1 GO:0060537 muscle tissue development 2/83 403/18722 0.536245576525216 0.586955095936151 IGF2/ENG 2 GO:0000910 cytokinesis 1/83 173/18722 0.538015733501322 0.5885593734341 MYH10 1 GO:0001659 temperature homeostasis 1/83 174/18722 0.540082944354704 0.590152815962489 PLAC8 1 GO:0045619 regulation of lymphocyte differentiation 1/83 174/18722 0.540082944354704 0.590152815962489 PRKDC 1 GO:0034655 nucleobase-containing compound catabolic process 2/83 407/18722 0.54160349541232 0.590732009139639 SMPDL3A/DHX36 2 GO:0048771 tissue remodeling 1/83 175/18722 0.542141016147812 0.590732009139639 LRP5 1 GO:0050954 sensory perception of mechanical stimulus 1/83 175/18722 0.542141016147812 0.590732009139639 SERPINE2 1 GO:0052126 movement in host environment 1/83 175/18722 0.542141016147812 0.590732009139639 ITGAV 1 GO:1905475 regulation of protein localization to membrane 1/83 175/18722 0.542141016147812 0.590732009139639 TCAF1 1 GO:0050728 negative regulation of inflammatory response 1/83 176/18722 0.544189988793508 0.59263056244386 SERPINF1 1 GO:0030324 lung development 1/83 177/18722 0.546229902032489 0.593514559094323 FSTL3 1 GO:0043405 regulation of MAP kinase activity 1/83 177/18722 0.546229902032489 0.593514559094323 FLT1 1 GO:0051302 regulation of cell division 1/83 177/18722 0.546229902032489 0.593514559094323 IGF2 1 GO:0071453 cellular response to oxygen levels 1/83 177/18722 0.546229902032489 0.593514559094323 EGLN3 1 GO:0035265 organ growth 1/83 178/18722 0.548260795434015 0.595386582906714 IGF2 1 GO:0006941 striated muscle contraction 1/83 179/18722 0.550282708396643 0.596242418907349 ALDOA 1 GO:0007416 synapse assembly 1/83 179/18722 0.550282708396643 0.596242418907349 APP 1 GO:0007626 locomotory behavior 1/83 179/18722 0.550282708396643 0.596242418907349 APP 1 GO:1901991 negative regulation of mitotic cell cycle phase transition 1/83 179/18722 0.550282708396643 0.596242418907349 PRKDC 1 GO:0043409 negative regulation of MAPK cascade 1/83 180/18722 0.552295680148953 0.5980882631529 SEMA6A 1 GO:0006479 protein methylation 1/83 181/18722 0.554299749750271 0.598247580272068 BTG1 1 GO:0008213 protein alkylation 1/83 181/18722 0.554299749750271 0.598247580272068 BTG1 1 GO:0030323 respiratory tube development 1/83 181/18722 0.554299749750271 0.598247580272068 FSTL3 1 GO:0032640 tumor necrosis factor production 1/83 181/18722 0.554299749750271 0.598247580272068 APP 1 GO:0032680 regulation of tumor necrosis factor production 1/83 181/18722 0.554299749750271 0.598247580272068 APP 1 GO:1905952 regulation of lipid localization 1/83 181/18722 0.554299749750271 0.598247580272068 ITGAV 1 GO:0051260 protein homooligomerization 1/83 182/18722 0.556294956091392 0.59973126052686 ALDOA 1 GO:0060401 cytosolic calcium ion transport 1/83 182/18722 0.556294956091392 0.59973126052686 ATP2B1 1 GO:2001257 regulation of cation channel activity 1/83 184/18722 0.560258933717871 0.603668070722768 APP 1 GO:0042060 wound healing 2/83 422/18722 0.56131917669517 0.604473520084548 F5/SERPINE2 2 GO:0002040 sprouting angiogenesis 1/83 185/18722 0.562227781948609 0.605114867765402 SEMA6A 1 GO:0031345 negative regulation of cell projection organization 1/83 186/18722 0.56418792081133 0.606211923806727 SEMA6A 1 GO:0071706 tumor necrosis factor superfamily cytokine production 1/83 186/18722 0.56418792081133 0.606211923806727 APP 1 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 1/83 186/18722 0.56418792081133 0.606211923806727 APP 1 GO:0008064 regulation of actin polymerization or depolymerization 1/83 187/18722 0.566139388364884 0.6079707987274 IQGAP2 1 GO:0031331 positive regulation of cellular catabolic process 2/83 427/18722 0.567757912731148 0.608367277617695 APP/DHX36 2 GO:0001906 cell killing 1/83 188/18722 0.568082222503849 0.608367277617695 GAPDH 1 GO:0006575 cellular modified amino acid metabolic process 1/83 188/18722 0.568082222503849 0.608367277617695 CLIC3 1 GO:0030832 regulation of actin filament length 1/83 188/18722 0.568082222503849 0.608367277617695 IQGAP2 1 GO:0048839 inner ear development 1/83 188/18722 0.568082222503849 0.608367277617695 LGR5 1 GO:0030041 actin filament polymerization 1/83 190/18722 0.571942141299193 0.611822998965877 IQGAP2 1 GO:0051216 cartilage development 1/83 190/18722 0.571942141299193 0.611822998965877 TGFBI 1 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 1/83 193/18722 0.577668206879369 0.61760655082844 IGF2 1 GO:0030073 insulin secretion 1/83 195/18722 0.581443474838706 0.621299191190282 LRP5 1 GO:0000280 nuclear division 2/83 439/18722 0.582937090139696 0.622207286162359 IGF2/LRP5 2 GO:0050804 modulation of chemical synaptic transmission 2/83 439/18722 0.582937090139696 0.622207286162359 APP/SERPINE2 2 GO:0090276 regulation of peptide hormone secretion 1/83 196/18722 0.583318586383392 0.622270876092217 LRP5 1 GO:0051090 regulation of DNA-binding transcription factor activity 2/83 440/18722 0.584184518980838 0.622507538693473 APP/LRP5 2 GO:0099177 regulation of trans-synaptic signaling 2/83 440/18722 0.584184518980838 0.622507538693473 APP/SERPINE2 2 GO:0046700 heterocycle catabolic process 2/83 445/18722 0.590381177796914 0.6284498942518 SMPDL3A/DHX36 2 GO:0002791 regulation of peptide secretion 1/83 200/18722 0.590736398269799 0.6284498942518 LRP5 1 GO:0045216 cell-cell junction organization 1/83 200/18722 0.590736398269799 0.6284498942518 SVEP1 1 GO:0006403 RNA localization 1/83 201/18722 0.592570372945515 0.629707823476459 DHX36 1 GO:0006473 protein acetylation 1/83 201/18722 0.592570372945515 0.629707823476459 MORF4L2 1 GO:0010876 lipid localization 2/83 448/18722 0.594066758339279 0.630608072706682 KCNN4/ITGAV 2 GO:0032388 positive regulation of intracellular transport 1/83 202/18722 0.594396227869413 0.630608072706682 TCAF1 1 GO:0090087 regulation of peptide transport 1/83 202/18722 0.594396227869413 0.630608072706682 LRP5 1 GO:0051701 biological process involved in interaction with host 1/83 203/18722 0.596213998554447 0.631843014915431 ITGAV 1 GO:0060541 respiratory system development 1/83 203/18722 0.596213998554447 0.631843014915431 FSTL3 1 GO:0044270 cellular nitrogen compound catabolic process 2/83 451/18722 0.597728009355736 0.633066731356072 SMPDL3A/DHX36 2 GO:1901888 regulation of cell junction assembly 1/83 204/18722 0.598023720360159 0.633066731356072 APP 1 GO:0008016 regulation of heart contraction 1/83 206/18722 0.601619158008646 0.63652426515091 ATP2B1 1 GO:1901215 negative regulation of neuron death 1/83 208/18722 0.605182820647767 0.639944415925674 SERPINF1 1 GO:0002685 regulation of leukocyte migration 1/83 210/18722 0.608714985697422 0.642624831978764 APP 1 GO:0031396 regulation of protein ubiquitination 1/83 210/18722 0.608714985697422 0.642624831978764 ISG15 1 GO:0050866 negative regulation of cell activation 1/83 210/18722 0.608714985697422 0.642624831978764 SERPINE2 1 GO:0042180 cellular ketone metabolic process 1/83 211/18722 0.610469342665179 0.644125130661458 CYP11A1 1 GO:0016570 histone modification 2/83 463/18722 0.612129589680334 0.64456066948897 IGF2/MORF4L2 2 GO:0022613 ribonucleoprotein complex biogenesis 2/83 463/18722 0.612129589680334 0.64456066948897 RPS21/PRKDC 2 GO:0023061 signal release 2/83 463/18722 0.612129589680334 0.64456066948897 WLS/LRP5 2 GO:0006469 negative regulation of protein kinase activity 1/83 212/18722 0.612215928185075 0.64456066948897 LRP5 1 GO:0043583 ear development 1/83 213/18722 0.613954776265066 0.646039511442772 LGR5 1 GO:0000082 G1/S transition of mitotic cell cycle 1/83 214/18722 0.615685920766119 0.647156544231054 PRKDC 1 GO:0072330 monocarboxylic acid biosynthetic process 1/83 214/18722 0.615685920766119 0.647156544231054 ACSS1 1 GO:0019439 aromatic compound catabolic process 2/83 467/18722 0.61684357709828 0.648020997027704 SMPDL3A/DHX36 2 GO:0007601 visual perception 1/83 215/18722 0.617409395402839 0.648263096856974 TGFBI 1 GO:0002377 immunoglobulin production 1/83 216/18722 0.619125233744092 0.649711768093013 PRKDC 1 GO:0008154 actin polymerization or depolymerization 1/83 217/18722 0.620833469213628 0.650797774398017 IQGAP2 1 GO:0070374 positive regulation of ERK1 and ERK2 cascade 1/83 217/18722 0.620833469213628 0.650797774398017 APP 1 GO:0007163 establishment or maintenance of cell polarity 1/83 218/18722 0.622534135090703 0.651873501154025 PDLIM1 1 GO:0042445 hormone metabolic process 1/83 218/18722 0.622534135090703 0.651873501154025 CYP11A1 1 GO:0050953 sensory perception of light stimulus 1/83 219/18722 0.624227264510692 0.652939016395654 TGFBI 1 GO:0071805 potassium ion transmembrane transport 1/83 219/18722 0.624227264510692 0.652939016395654 KCNN4 1 GO:0022618 ribonucleoprotein complex assembly 1/83 220/18722 0.625912890465705 0.653994387713626 PRKDC 1 GO:0044706 multi-multicellular organism process 1/83 220/18722 0.625912890465705 0.653994387713626 SERPINE2 1 GO:0010810 regulation of cell-substrate adhesion 1/83 221/18722 0.627591045805201 0.655393566472962 UTRN 1 GO:0002274 myeloid leukocyte activation 1/83 223/18722 0.630925075325855 0.658519530564189 APP 1 GO:2001234 negative regulation of apoptotic signaling pathway 1/83 224/18722 0.632581014498132 0.659891581772741 ITGAV 1 GO:0002703 regulation of leukocyte mediated immunity 1/83 226/18722 0.635870903091738 0.662965725823263 DHX36 1 GO:0071826 ribonucleoprotein complex subunit organization 1/83 227/18722 0.637504916664586 0.663971145886475 PRKDC 1 GO:0034660 ncRNA metabolic process 2/83 485/18722 0.637522217674753 0.663971145886475 RPS21/PRKDC 2 GO:0033157 regulation of intracellular protein transport 1/83 229/18722 0.640751241701951 0.666036873783813 TCAF1 1 GO:0071356 cellular response to tumor necrosis factor 1/83 229/18722 0.640751241701951 0.666036873783813 KRT8 1 GO:0071695 anatomical structure maturation 1/83 229/18722 0.640751241701951 0.666036873783813 APP 1 GO:0048285 organelle fission 2/83 488/18722 0.640883903382251 0.666036873783813 IGF2/LRP5 2 GO:0016197 endosomal transport 1/83 230/18722 0.642363616489099 0.66721594340324 TINAGL1 1 GO:0009896 positive regulation of catabolic process 2/83 492/18722 0.645328629179624 0.669823354940355 APP/DHX36 2 GO:0006402 mRNA catabolic process 1/83 232/18722 0.645566947880952 0.669823354940355 DHX36 1 GO:1901361 organic cyclic compound catabolic process 2/83 495/18722 0.648634086155166 0.672644682692025 SMPDL3A/DHX36 2 GO:0002699 positive regulation of immune effector process 1/83 235/18722 0.65031886728217 0.67403022544581 DHX36 1 GO:0030072 peptide hormone secretion 1/83 236/18722 0.651888810161793 0.674933620804898 LRP5 1 GO:0048738 cardiac muscle tissue development 1/83 236/18722 0.651888810161793 0.674933620804898 ENG 1 GO:0033673 negative regulation of kinase activity 1/83 237/18722 0.653451789105673 0.676189672559564 LRP5 1 GO:0072593 reactive oxygen species metabolic process 1/83 239/18722 0.656556977116086 0.679039399018402 PAGE4 1 GO:0032886 regulation of microtubule-based process 1/83 240/18722 0.65809924681794 0.679906918278502 MET 1 GO:0050851 antigen receptor-mediated signaling pathway 1/83 240/18722 0.65809924681794 0.679906918278502 KCNN4 1 GO:0006813 potassium ion transport 1/83 241/18722 0.65963467385582 0.680402254302722 KCNN4 1 GO:0044843 cell cycle G1/S phase transition 1/83 241/18722 0.65963467385582 0.680402254302722 PRKDC 1 GO:0060047 heart contraction 1/83 241/18722 0.65963467385582 0.680402254302722 ATP2B1 1 GO:0002790 peptide secretion 1/83 242/18722 0.661163288220301 0.681251938235523 LRP5 1 GO:1903320 regulation of protein modification by small protein conjugation or removal 1/83 242/18722 0.661163288220301 0.681251938235523 ISG15 1 GO:0043543 protein acylation 1/83 243/18722 0.662685119772126 0.682456226169163 MORF4L2 1 GO:0021537 telencephalon development 1/83 248/18722 0.670193571449123 0.689821178706685 ADGRG1 1 GO:0046883 regulation of hormone secretion 1/83 249/18722 0.671675325999828 0.690610853807269 LRP5 1 GO:1901988 negative regulation of cell cycle phase transition 1/83 249/18722 0.671675325999828 0.690610853807269 PRKDC 1 GO:0003015 heart process 1/83 251/18722 0.674619131814108 0.693268889844056 ATP2B1 1 GO:0034612 response to tumor necrosis factor 1/83 253/18722 0.677536858234128 0.695897315072566 KRT8 1 GO:0051924 regulation of calcium ion transport 1/83 255/18722 0.680428733506299 0.69849641097593 ATP2B1 1 GO:0034976 response to endoplasmic reticulum stress 1/83 256/18722 0.681865047748947 0.699228189548389 JUN 1 GO:1903522 regulation of blood circulation 1/83 256/18722 0.681865047748947 0.699228189548389 ATP2B1 1 GO:0030217 T cell differentiation 1/83 257/18722 0.683294983903871 0.700323013725442 PRKDC 1 GO:0045165 cell fate commitment 1/83 258/18722 0.684718569949686 0.701410172608767 PRKDC 1 GO:0006260 DNA replication 1/83 260/18722 0.687546803022841 0.703561657090075 JUN 1 GO:0090150 establishment of protein localization to membrane 1/83 260/18722 0.687546803022841 0.703561657090075 TCAF1 1 GO:0090305 nucleic acid phosphodiester bond hydrolysis 1/83 261/18722 0.688951505403358 0.704626063462799 RPS21 1 GO:0003018 vascular process in circulatory system 1/83 263/18722 0.69174221933688 0.707106139597139 ATP2B1 1 GO:0015833 peptide transport 1/83 264/18722 0.693128285526546 0.708148507358781 LRP5 1 GO:0030522 intracellular receptor signaling pathway 1/83 265/18722 0.694508194092008 0.709183486096065 PARP1 1 GO:0051348 negative regulation of transferase activity 1/83 268/18722 0.698611243690188 0.7129965860893 LRP5 1 GO:0046942 carboxylic acid transport 1/83 273/18722 0.705329006458102 0.719472807115309 SLC26A2 1 GO:0006401 RNA catabolic process 1/83 278/18722 0.711898798810208 0.72540873911446 DHX36 1 GO:0007281 germ cell development 1/83 278/18722 0.711898798810208 0.72540873911446 LGR5 1 GO:0002263 cell activation involved in immune response 1/83 279/18722 0.713195285456204 0.726346937190117 APP 1 GO:0021700 developmental maturation 1/83 280/18722 0.714486007752313 0.72727827961307 APP 1 GO:1903311 regulation of mRNA metabolic process 1/83 288/18722 0.724607284724056 0.737192569142947 DHX36 1 GO:0034504 protein localization to nucleus 1/83 290/18722 0.727081707406675 0.738932145329707 PARP1 1 GO:0071103 DNA conformation change 1/83 290/18722 0.727081707406675 0.738932145329707 DHX36 1 GO:0002429 immune response-activating cell surface receptor signaling pathway 1/83 291/18722 0.728310668902185 0.739015497631456 KCNN4 1 GO:0002757 immune response-activating signal transduction 1/83 291/18722 0.728310668902185 0.739015497631456 KCNN4 1 GO:0016236 macroautophagy 1/83 291/18722 0.728310668902185 0.739015497631456 GAPDH 1 GO:0010948 negative regulation of cell cycle process 1/83 294/18722 0.731964843315827 0.742333705209598 PRKDC 1 GO:0046879 hormone secretion 1/83 295/18722 0.733172077850491 0.743168131350287 LRP5 1 GO:0016050 vesicle organization 1/83 300/18722 0.739128138548932 0.748812731559269 SERPINE2 1 GO:0042886 amide transport 1/83 301/18722 0.740303492175055 0.749610607844097 LRP5 1 GO:0015849 organic acid transport 1/83 303/18722 0.742638526381561 0.751581293976731 SLC26A2 1 GO:0009914 hormone transport 1/83 306/18722 0.746102238689269 0.754691589422479 LRP5 1 GO:0006605 protein targeting 1/83 314/18722 0.755115251168636 0.763009817307357 TCAF1 1 GO:0046394 carboxylic acid biosynthetic process 1/83 314/18722 0.755115251168636 0.763009817307357 ACSS1 1 GO:0002768 immune response-regulating cell surface receptor signaling pathway 1/83 315/18722 0.756219414258217 0.763726294546047 KCNN4 1 GO:0016053 organic acid biosynthetic process 1/83 316/18722 0.757318658492289 0.764437058415454 ACSS1 1 GO:0007204 positive regulation of cytosolic calcium ion concentration 1/83 319/18722 0.760587094057396 0.767335518169596 ITGAV 1 GO:0019216 regulation of lipid metabolic process 1/83 331/18722 0.773231557573295 0.779685237761701 FLT1 1 GO:0042113 B cell activation 1/83 334/18722 0.776288157865797 0.782359233135863 PRKDC 1 GO:0032386 regulation of intracellular transport 1/83 337/18722 0.779304048163328 0.784989434653316 TCAF1 1 GO:0032496 response to lipopolysaccharide 1/83 343/18722 0.785215834529671 0.790532400075966 JUN 1 GO:0015711 organic anion transport 1/83 354/18722 0.795650596279095 0.800620823845648 SLC26A2 1 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1/83 356/18722 0.797493272571716 0.802057490052615 EBI3 1 GO:0001818 negative regulation of cytokine production 1/83 357/18722 0.798408445084867 0.802560335074908 ATP2B1 1 GO:0002237 response to molecule of bacterial origin 1/83 363/18722 0.803814296813148 0.807574342900112 JUN 1 GO:0018205 peptidyl-lysine modification 1/83 376/18722 0.815040505376626 0.818002750204059 MORF4L2 1 GO:0044282 small molecule catabolic process 1/83 376/18722 0.815040505376626 0.818002750204059 LRP5 1 GO:0022412 cellular process involved in reproduction in multicellular organism 1/83 384/18722 0.821630967579371 0.824189237327931 LGR5 1 GO:0006631 fatty acid metabolic process 1/83 390/18722 0.826421051053285 0.828134728712286 ACSS1 1 GO:0051656 establishment of organelle localization 1/83 390/18722 0.826421051053285 0.828134728712286 ARMCX3 1 GO:0042176 regulation of protein catabolic process 1/83 391/18722 0.827206947450982 0.828492761358937 SERPINE2 1 GO:0034329 cell junction assembly 1/83 420/18722 0.848529935168252 0.849408785437716 APP 1 GO:0002443 leukocyte mediated immunity 1/83 440/18722 0.861698798345235 0.862144812216014 DHX36 1 GO:0002764 immune response-regulating signaling pathway 1/83 468/18722 0.878254776719416 0.878254776719416 KCNN4 1