ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0002478 antigen processing and presentation of exogenous peptide antigen 13/320 38/18722 3.07512875743226e-14 1.27064320257101e-10 HLA-A/CTSS/HLA-DMA/HLA-DPA1/FCER1G/HLA-DRB1/HLA-DRA/IFI30/HLA-DPB1/HLA-E/CD74/B2M/CTSL 13 GO:0048002 antigen processing and presentation of peptide antigen 15/320 62/18722 1.00951053373989e-13 2.08564876270661e-10 HLA-A/HLA-B/CTSS/HLA-DMA/HLA-DPA1/FCER1G/HLA-DRB1/HLA-DRA/IFI30/HLA-DPB1/HLA-E/HLA-C/CD74/B2M/CTSL 15 GO:0019884 antigen processing and presentation of exogenous antigen 13/320 47/18722 6.95876635321461e-13 9.58454085716092e-10 HLA-A/CTSS/HLA-DMA/HLA-DPA1/FCER1G/HLA-DRB1/HLA-DRA/IFI30/HLA-DPB1/HLA-E/CD74/B2M/CTSL 13 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 11/320 30/18722 1.25367646440748e-12 1.29504778773292e-09 CTSS/HLA-DMA/HLA-DPA1/FCER1G/HLA-DRB1/HLA-DRA/IFI30/HLA-DPB1/CD74/B2M/CTSL 11 GO:0019882 antigen processing and presentation 17/320 106/18722 2.93429787307791e-12 2.42490376231159e-09 HLA-A/FGL2/HLA-B/CTSS/HLA-DMA/HLA-DPA1/FCER1G/HLA-DRB1/HLA-DRA/CD68/IFI30/HLA-DPB1/HLA-E/HLA-C/CD74/B2M/CTSL 17 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 11/320 34/18722 6.17766875850976e-12 4.25435455169372e-09 CTSS/HLA-DMA/HLA-DPA1/FCER1G/HLA-DRB1/HLA-DRA/IFI30/HLA-DPB1/CD74/B2M/CTSL 11 GO:0007159 leukocyte cell-cell adhesion 29/320 371/18722 1.01169038601404e-11 5.97186382144288e-09 PTPRC/HLA-A/FGL2/AIF1/TNFSF13B/IGF2/ITGB2/HLA-DMA/CORO1A/HLA-DPA1/LAPTM5/CAV1/HLA-DRB1/MSN/HLA-DRA/EFNB1/EZR/HLA-DPB1/HLA-E/ANXA1/HMGB1/ITGB1/CD74/B2M/S100A9/RHOA/SOX4/TFRC/CEBPB 29 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 11/320 36/18722 1.25838538719137e-11 6.49956052484344e-09 CTSS/HLA-DMA/HLA-DPA1/FCER1G/HLA-DRB1/HLA-DRA/IFI30/HLA-DPB1/CD74/B2M/CTSL 11 GO:0034341 response to interferon-gamma 18/320 141/18722 3.51765364169286e-11 1.61499387194166e-08 GAPDH/IFITM2/VIM/AIF1/CCL3L3/BST2/HLA-DPA1/CCL3/GBP2/ACTG1/PARP14/FLNB/CDC42/IFNGR2/CD74/GBP1/STAT1/ACTR3 18 GO:0070663 regulation of leukocyte proliferation 23/320 245/18722 3.99543803746783e-11 1.65091499708171e-08 PTPRC/MNDA/HLA-A/TNFRSF1B/AIF1/TNFSF13B/LST1/IGF2/TYROBP/CORO1A/BST2/HLA-DPA1/HLA-DRB1/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/SLC39A10/CTNNB1/TFRC/CEBPB 23 GO:0050670 regulation of lymphocyte proliferation 22/320 225/18722 4.85028670703805e-11 1.82194406122557e-08 PTPRC/MNDA/HLA-A/TNFRSF1B/AIF1/TNFSF13B/LST1/IGF2/TYROBP/CORO1A/HLA-DPA1/HLA-DRB1/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/SLC39A10/CTNNB1/TFRC/CEBPB 22 GO:0032944 regulation of mononuclear cell proliferation 22/320 227/18722 5.7693664036768e-11 1.98658516499938e-08 PTPRC/MNDA/HLA-A/TNFRSF1B/AIF1/TNFSF13B/LST1/IGF2/TYROBP/CORO1A/HLA-DPA1/HLA-DRB1/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/SLC39A10/CTNNB1/TFRC/CEBPB 22 GO:0042110 T cell activation 32/320 487/18722 7.83082798680277e-11 2.48899855703608e-08 PTPRC/HLA-A/FGL2/TNFRSF1B/AIF1/TNFSF13B/IGF2/HLA-DMA/CORO1A/HLA-DPA1/LAPTM5/FCER1G/CAV1/HLA-DRB1/LCP1/MSN/HLA-DRA/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/ZFP36L2/CD74/MYH9/B2M/CTSL/RHOA/CTNNB1/SOX4/TFRC/CEBPB 32 GO:0050863 regulation of T cell activation 26/320 329/18722 9.8066808484541e-11 2.89437180470088e-08 PTPRC/HLA-A/FGL2/TNFRSF1B/AIF1/TNFSF13B/IGF2/HLA-DMA/CORO1A/HLA-DPA1/LAPTM5/CAV1/HLA-DRB1/HLA-DRA/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/B2M/RHOA/CTNNB1/SOX4/TFRC/CEBPB 26 GO:0045785 positive regulation of cell adhesion 30/320 437/18722 1.09806650501712e-10 3.02480719915382e-08 PTPRC/HLA-A/AIF1/TNFSF13B/IGF2/ITGB2/HLA-DMA/FLNA/CORO1A/MYADM/PLAUR/PLEKHA2/HLA-DPA1/FN1/CAV1/HLA-DRB1/HLA-DRA/EFNB1/CCDC80/HLA-DPB1/HLA-E/ANXA1/CDC42/HMGB1/CD74/B2M/PLPP3/RHOA/SOX4/TFRC 30 GO:0022409 positive regulation of cell-cell adhesion 24/320 284/18722 1.34153159058831e-10 3.46450533269432e-08 PTPRC/HLA-A/AIF1/TNFSF13B/IGF2/ITGB2/HLA-DMA/CORO1A/PLAUR/HLA-DPA1/CAV1/HLA-DRB1/HLA-DRA/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/B2M/PLPP3/RHOA/SOX4/TFRC 24 GO:0050870 positive regulation of T cell activation 21/320 216/18722 1.50242253121543e-10 3.61006176735061e-08 PTPRC/HLA-A/AIF1/TNFSF13B/IGF2/HLA-DMA/CORO1A/HLA-DPA1/CAV1/HLA-DRB1/HLA-DRA/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/B2M/RHOA/SOX4/TFRC 21 GO:1903039 positive regulation of leukocyte cell-cell adhesion 22/320 239/18722 1.57263097319242e-10 3.61006176735061e-08 PTPRC/HLA-A/AIF1/TNFSF13B/IGF2/ITGB2/HLA-DMA/CORO1A/HLA-DPA1/CAV1/HLA-DRB1/HLA-DRA/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/B2M/RHOA/SOX4/TFRC 22 GO:0002683 negative regulation of immune system process 29/320 434/18722 4.29693748031737e-10 9.34470824666913e-08 PTPRC/MNDA/SERPINB9/HLA-A/FGL2/HLA-B/TSC22D3/LST1/TYROBP/BST2/LAPTM5/HLA-DRB1/CD68/CCL3/ISG15/HTRA1/EZR/GPX1/HLA-E/ANXA1/FBN1/SAMHD1/PARP14/HMGB1/CD74/GBP1/HMOX1/CTNNB1/CEBPB 29 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 19/320 186/18722 4.95066888309654e-10 1.02280819124775e-07 GAPDH/TNFSF10/FLNA/BST2/HLA-DRB1/NEK6/MTDH/WLS/LITAF/CD74/REL/HMOX1/S100A4/RHOA/TMED4/CARD16/CTNNB1/GJA1/TFRC 19 GO:1903037 regulation of leukocyte cell-cell adhesion 25/320 336/18722 8.05749570318172e-10 1.5854082021689e-07 PTPRC/HLA-A/FGL2/AIF1/TNFSF13B/IGF2/ITGB2/HLA-DMA/CORO1A/HLA-DPA1/LAPTM5/CAV1/HLA-DRB1/HLA-DRA/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/B2M/RHOA/SOX4/TFRC/CEBPB 25 GO:0022407 regulation of cell-cell adhesion 29/320 448/18722 8.97287084096698e-10 1.6852682870398e-07 PTPRC/HLA-A/FGL2/FXYD5/AIF1/TNFSF13B/IGF2/ITGB2/HLA-DMA/CORO1A/MYADM/PLAUR/HLA-DPA1/LAPTM5/CAV1/HLA-DRB1/HLA-DRA/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/B2M/PLPP3/RHOA/SOX4/TFRC/CEBPB 29 GO:0046651 lymphocyte proliferation 23/320 288/18722 9.99925614084454e-10 1.75995650749783e-07 PTPRC/MNDA/HLA-A/TNFRSF1B/AIF1/TNFSF13B/LST1/IGF2/TYROBP/CORO1A/HLA-DPA1/HLA-DRB1/MSN/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/SLC39A10/CTNNB1/TFRC/CEBPB 23 GO:0042060 wound healing 28/320 422/18722 1.0222399849939e-09 1.75995650749783e-07 SERPINA1/PLEK/FLNA/PLAUR/CXCR4/FN1/FCER1G/CAV1/F5/GPX1/ACTG1/FBLN1/ANXA1/DSP/HMGB1/ITGB1/TGFBR1/MYH9/PLEC/TFPI2/HMOX1/ANXA6/DST/PLPP3/RHOA/ACTB/HSPB1/GJA1 28 GO:0032970 regulation of actin filament-based process 27/320 396/18722 1.14023026904346e-09 1.88457258867503e-07 TMSB4X/PLEK/GMFG/FLNA/CORO1A/MYADM/BST2/COTL1/CAV1/ARHGDIB/ACTG1/CAPG/DSP/CDC42/PFN1/SRI/STMN1/IQGAP2/TGFBR1/MYH9/PDE4B/CAPZA1/CAPZB/VASP/ACTR3/RHOA/ID1 27 GO:0032943 mononuclear cell proliferation 23/320 291/18722 1.22332618696396e-09 1.94414761712888e-07 PTPRC/MNDA/HLA-A/TNFRSF1B/AIF1/TNFSF13B/LST1/IGF2/TYROBP/CORO1A/HLA-DPA1/HLA-DRB1/MSN/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/SLC39A10/CTNNB1/TFRC/CEBPB 23 GO:0070661 leukocyte proliferation 24/320 318/18722 1.3376493414837e-09 2.0470989181521e-07 PTPRC/MNDA/HLA-A/TNFRSF1B/AIF1/TNFSF13B/LST1/IGF2/TYROBP/CORO1A/BST2/HLA-DPA1/HLA-DRB1/MSN/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/SLC39A10/CTNNB1/TFRC/CEBPB 24 GO:0071346 cellular response to interferon-gamma 15/320 118/18722 1.65806178333342e-09 2.44682546026204e-07 GAPDH/VIM/AIF1/CCL3L3/HLA-DPA1/CCL3/GBP2/ACTG1/PARP14/FLNB/CDC42/IFNGR2/GBP1/STAT1/ACTR3 15 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 21/320 249/18722 2.05067706736852e-09 2.92186125598853e-07 GAPDH/TNFSF10/FLNA/BST2/HLA-DRB1/NEK6/MTDH/WLS/LITAF/CD74/REL/STAT1/HMOX1/S100A4/RHOA/TMED4/CARD16/HSPB1/CTNNB1/GJA1/TFRC 21 GO:0042129 regulation of T cell proliferation 17/320 171/18722 6.23299026421958e-09 8.45356829304132e-07 PTPRC/HLA-A/TNFRSF1B/AIF1/TNFSF13B/IGF2/CORO1A/HLA-DPA1/HLA-DRB1/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CTNNB1/TFRC/CEBPB 17 GO:0070665 positive regulation of leukocyte proliferation 16/320 150/18722 6.34222209787708e-09 8.45356829304132e-07 PTPRC/HLA-A/AIF1/TNFSF13B/IGF2/CORO1A/BST2/HLA-DPA1/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/SLC39A10/TFRC 16 GO:0019883 antigen processing and presentation of endogenous antigen 8/320 26/18722 7.97837528847619e-09 1.03020770912449e-06 HLA-A/HLA-B/HLA-DRB1/HLA-DRA/HLA-E/HLA-C/CD74/B2M 8 GO:0042098 T cell proliferation 18/320 199/18722 9.98133063818727e-09 1.24978358172696e-06 PTPRC/HLA-A/TNFRSF1B/AIF1/TNFSF13B/IGF2/CORO1A/HLA-DPA1/HLA-DRB1/MSN/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CTNNB1/TFRC/CEBPB 18 GO:0007015 actin filament organization 27/320 441/18722 1.14636379946866e-08 1.39316918217779e-06 TMSB4X/ALDOA/AIF1/PLEK/GMFG/FLNA/CORO1A/MYADM/MARCKS/COTL1/LCP1/EZR/ACTG1/CAPG/TPM4/CDC42/PFN1/STMN1/IQGAP2/TGFBR1/PLEC/CAPZA1/CAPZB/VASP/ACTR3/RHOA/ID1 27 GO:0050671 positive regulation of lymphocyte proliferation 15/320 137/18722 1.3286027201957e-08 1.56851041138532e-06 PTPRC/HLA-A/AIF1/TNFSF13B/IGF2/CORO1A/HLA-DPA1/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/SLC39A10/TFRC 15 GO:0032946 positive regulation of mononuclear cell proliferation 15/320 138/18722 1.46789307988677e-08 1.68481505724781e-06 PTPRC/HLA-A/AIF1/TNFSF13B/IGF2/CORO1A/HLA-DPA1/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/SLC39A10/TFRC 15 GO:0002483 antigen processing and presentation of endogenous peptide antigen 7/320 19/18722 1.68637838194563e-08 1.82316791605124e-06 HLA-A/HLA-B/HLA-DRB1/HLA-DRA/HLA-E/HLA-C/B2M 7 GO:0050867 positive regulation of cell activation 26/320 420/18722 1.7297096179375e-08 1.82316791605124e-06 PTPRC/HLA-A/AIF1/PLEK/TNFSF13B/IGF2/ITGB2/HLA-DMA/TYROBP/CORO1A/HLA-DPA1/CAV1/HLA-DRB1/HLA-DRA/EFNB1/CCL3/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/B2M/SLC39A10/RHOA/SOX4/TFRC 26 GO:0007249 I-kappaB kinase/NF-kappaB signaling 21/320 281/18722 1.75447985148495e-08 1.82316791605124e-06 GAPDH/TNFSF10/FLNA/BST2/HLA-DRB1/NEK6/MTDH/WLS/LITAF/CD74/REL/STAT1/HMOX1/S100A4/RHOA/TMED4/CARD16/HSPB1/CTNNB1/GJA1/TFRC 21 GO:0042102 positive regulation of T cell proliferation 13/320 101/18722 1.7649253785588e-08 1.82316791605124e-06 PTPRC/HLA-A/AIF1/TNFSF13B/IGF2/CORO1A/HLA-DPA1/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/TFRC 13 GO:0043254 regulation of protein-containing complex assembly 26/320 427/18722 2.41832401737198e-08 2.43719874141e-06 TMSB4X/PLEK/GMFG/CORO1A/MYADM/COTL1/LCP1/MSN/ISG15/LMO4/CAPG/ISL1/CDC42/ICE1/HMGB1/PFN1/STMN1/IQGAP2/PARP1/CAPZA1/CAPZB/VASP/HSPA1A/ACTR3/RHOA/TFRC 26 GO:0001819 positive regulation of cytokine production 27/320 467/18722 3.77717043594635e-08 3.71601624793579e-06 PTPRC/MNDA/GAPDH/HLA-A/AIF1/CYBB/FCN1/TYROBP/HLA-DPA1/LAPTM5/FCER1G/CCL3/ISG15/CYBA/HLA-DPB1/HLA-E/ANXA1/ISL1/HMGB1/CD74/PDE4B/B2M/STAT1/HMOX1/HSPA1A/HSPB1/CEBPB 27 GO:0002696 positive regulation of leukocyte activation 25/320 409/18722 4.21386411271828e-08 4.04922942180278e-06 PTPRC/HLA-A/AIF1/TNFSF13B/IGF2/ITGB2/HLA-DMA/TYROBP/CORO1A/HLA-DPA1/CAV1/HLA-DRB1/HLA-DRA/EFNB1/CCL3/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/B2M/SLC39A10/RHOA/SOX4/TFRC 25 GO:0016032 viral process 25/320 415/18722 5.59007625584198e-08 5.24958979298615e-06 IFITM2/MX1/FCN1/APOBEC3A/BST2/CXCR4/CAV1/HLA-DRB1/CCL3/ISG15/ZFP36/CDC42/ITGB1/DEK/JUN/CD74/SIVA1/SSB/CTSB/STAT1/CDK1/CTSL/HSPA1A/TOP2A/TFRC 25 GO:0001818 negative regulation of cytokine production 23/320 357/18722 5.76166086777557e-08 5.2904850456997e-06 PTPRC/TMSB4X/TSPO/TYROBP/SRGN/BST2/LAPTM5/FN1/HLA-DRB1/EZR/ANXA4/KLF2/ZFP36/SERPINB1/ANXA1/ATP2B1/HMGB1/REL/GBP1/HMOX1/EZH2/CARD16/PDCD4 23 GO:0110053 regulation of actin filament organization 20/320 277/18722 6.83484850598682e-08 6.13947696233424e-06 TMSB4X/PLEK/GMFG/FLNA/CORO1A/MYADM/COTL1/ACTG1/CAPG/CDC42/PFN1/STMN1/IQGAP2/TGFBR1/CAPZA1/CAPZB/VASP/ACTR3/RHOA/ID1 20 GO:0051251 positive regulation of lymphocyte activation 23/320 362/18722 7.4201130688918e-08 6.52338451077891e-06 PTPRC/HLA-A/AIF1/TNFSF13B/IGF2/HLA-DMA/TYROBP/CORO1A/HLA-DPA1/CAV1/HLA-DRB1/HLA-DRA/EFNB1/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/B2M/SLC39A10/RHOA/SOX4/TFRC 23 GO:0071356 cellular response to tumor necrosis factor 18/320 229/18722 8.75662424594937e-08 7.53799403838808e-06 TMSB4X/TNFRSF1B/TNFSF13B/CCL3L3/LAPTM5/KRT8/CCL3/GBP2/CYBA/KLF2/ZFP36/KRT18/ZFP36L2/GBP1/STAT1/HSPA1A/YBX3/CARD16 18 GO:1903706 regulation of hemopoiesis 23/320 367/18722 9.51136099350793e-08 8.02060073983159e-06 PTPRC/FGL2/HLA-B/EVI2B/TYROBP/HLA-DRB1/HLA-DRA/CCL3/ISG15/ZFP36/ANXA1/FBN1/HMGB1/ZFP36L2/JUN/CD74/B2M/STAT1/HSPA1A/RHOA/CTNNB1/SOX4/CEBPB 23 GO:0002399 MHC class II protein complex assembly 6/320 16/18722 1.6494943042056e-07 1.33641381666226e-05 HLA-DMA/HLA-DPA1/HLA-DRB1/HLA-DRA/HLA-DPB1/B2M 6 GO:0002503 peptide antigen assembly with MHC class II protein complex 6/320 16/18722 1.6494943042056e-07 1.33641381666226e-05 HLA-DMA/HLA-DPA1/HLA-DRB1/HLA-DRA/HLA-DPB1/B2M 6 GO:0032956 regulation of actin cytoskeleton organization 22/320 357/18722 2.43306795761718e-07 1.90704331330498e-05 TMSB4X/PLEK/GMFG/FLNA/CORO1A/MYADM/BST2/COTL1/ARHGDIB/ACTG1/CAPG/CDC42/PFN1/STMN1/IQGAP2/TGFBR1/CAPZA1/CAPZB/VASP/ACTR3/RHOA/ID1 22 GO:0048872 homeostasis of number of cells 19/320 272/18722 2.44611073584618e-07 1.90704331330498e-05 TSC22D3/TNFSF13B/CORO1A/ISG15/RPS17/KLF2/ZFP36/ANXA1/PMAIP1/HMGB1/CD74/PDE4B/B2M/STAT1/HMOX1/UBA5/HSPA1A/EZH2/SOX4 19 GO:0007229 integrin-mediated signaling pathway 12/320 107/18722 2.94025587803758e-07 2.24984023852801e-05 PLEK/ITGB2/FLNA/FN1/ISG15/CD63/CDC42/ITGB1/MYH9/DST/PTPRA/PLPP3 12 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 7/320 28/18722 3.47177984814729e-07 2.60825351500811e-05 HLA-A/HLA-B/FCER1G/IFI30/HLA-E/HLA-C/B2M 7 GO:0002501 peptide antigen assembly with MHC protein complex 6/320 18/18722 3.71494013973908e-07 2.72328456532253e-05 HLA-DMA/HLA-DPA1/HLA-DRB1/HLA-DRA/HLA-DPB1/B2M 6 GO:0062197 cellular response to chemical stress 21/320 337/18722 3.82609104801163e-07 2.72328456532253e-05 AIF1/NCF1/TSPO/PAGE4/CAV1/GPX1/KLF2/ANXA1/SOD2/EFHD1/JUN/PLEC/PARP1/HMOX1/CDK1/HSPA1A/SOD3/EZH2/YBX3/HSPB1/CTNNB1 21 GO:0034109 homotypic cell-cell adhesion 11/320 90/18722 3.83441587891268e-07 2.72328456532253e-05 PLEK/FLNA/PLAUR/FN1/ACTG1/DSP/CD99/MYH9/PLPP3/ACTB/HSPB1 11 GO:0034612 response to tumor necrosis factor 18/320 253/18722 3.88852345968125e-07 2.72328456532253e-05 TMSB4X/TNFRSF1B/TNFSF13B/CCL3L3/LAPTM5/KRT8/CCL3/GBP2/CYBA/KLF2/ZFP36/KRT18/ZFP36L2/GBP1/STAT1/HSPA1A/YBX3/CARD16 18 GO:0002697 regulation of immune effector process 21/320 339/18722 4.21679987032906e-07 2.89704666468938e-05 PTPRC/SERPINB9/HLA-A/FGL2/HLA-B/TNFRSF1B/ITGB2/NCF1/TYROBP/BST2/LAPTM5/HLA-DRB1/HLA-DRA/HLA-E/ANXA1/HMGB1/CD74/B2M/HMOX1/STXBP2/TFRC 21 GO:0050900 leukocyte migration 22/320 369/18722 4.27685979056274e-07 2.89704666468938e-05 AIF1/ITGB2/CCL3L3/CORO1A/CXCR4/FCER1G/MSN/CCL3/ANXA1/PGF/CD99/CDC42/HMGB1/ITGB1/FLT1/CD74/MYH9/PLEC/PDE4B/HMOX1/S100A9/RHOA 22 GO:0001916 positive regulation of T cell mediated cytotoxicity 7/320 29/18722 4.50973982904468e-07 3.00552338284074e-05 PTPRC/HLA-A/HLA-B/HLA-DRB1/HLA-DRA/HLA-E/B2M 7 GO:0002396 MHC protein complex assembly 6/320 19/18722 5.35169504814421e-07 3.51003237125903e-05 HLA-DMA/HLA-DPA1/HLA-DRB1/HLA-DRA/HLA-DPB1/B2M 6 GO:0050673 epithelial cell proliferation 24/320 437/18722 5.62098648764978e-07 3.62904940108889e-05 IGF2/CAV1/NRP2/CYBA/HTRA1/GPX1/ZFP36/SERPINB1/PGF/ISL1/CDC42/HMGB1/FLT1/TGFBR1/B2M/STAT1/HMOX1/MAGED1/ID1/CTNNB1/LGR5/PDCD6/GJA1/CEBPB 24 GO:0019058 viral life cycle 20/320 317/18722 5.99334967197704e-07 3.80992628378602e-05 IFITM2/MX1/FCN1/APOBEC3A/BST2/CXCR4/CAV1/HLA-DRB1/ISG15/CDC42/ITGB1/DEK/CD74/SIVA1/CTSB/CDK1/CTSL/HSPA1A/TOP2A/TFRC 20 GO:0002443 leukocyte mediated immunity 24/320 440/18722 6.35265405726734e-07 3.97714644918616e-05 PTPRC/SERPINB9/HLA-A/HLA-B/TNFRSF1B/ITGB2/HLA-DMA/TYROBP/CORO1A/BST2/HLA-DPA1/FCER1G/HLA-DRB1/HLA-DRA/CCL3/HLA-DPB1/HLA-E/HMGB1/CD74/B2M/HMOX1/TUBB/STXBP2/TFRC 24 GO:0044403 biological process involved in symbiotic interaction 19/320 290/18722 6.52275472989308e-07 4.02268993192809e-05 GAPDH/SERPINB9/IFITM2/FCN1/CXCR4/FN1/CAV1/HLA-DRB1/CCL3/GPX1/ITGB1/JUN/CD74/SIVA1/CTSB/CDK1/CTSL/HSPA1A/TFRC 19 GO:0001667 ameboidal-type cell migration 25/320 475/18722 7.12490207273138e-07 4.32942578890089e-05 TMSB4X/ZEB2/FN1/NRP2/EFNB1/ARHGDIB/GPX1/ANXA1/ISL1/S100P/HMGB1/PFN1/ITGB1/TGFBR1/MYH9/PLEC/SEMA6D/HMOX1/ANXA6/PLPP3/RHOA/ID1/HSPB1/PDCD6/GJA1 25 GO:0030099 myeloid cell differentiation 22/320 381/18722 7.33452565372208e-07 4.39221159437386e-05 EVI2B/TYROBP/HLA-DRB1/CCL3/ISG15/KLF2/ZFP36/FBN1/CDC42/HMGB1/JUN/CD74/MYH9/B2M/PARP1/STAT1/UBA5/HSPA1A/SNX10/CTNNB1/TFRC/CEBPB 22 GO:1902903 regulation of supramolecular fiber organization 22/320 382/18722 7.66355914323095e-07 4.5236894828329e-05 TMSB4X/PLEK/GMFG/FLNA/CORO1A/MYADM/COTL1/GPX1/ACTG1/CAPG/CDC42/PFN1/STMN1/IQGAP2/TGFBR1/CAPZA1/CAPZB/VASP/HSPA1A/ACTR3/RHOA/ID1 22 GO:0006979 response to oxidative stress 24/320 446/18722 8.08560087200858e-07 4.70559194410415e-05 TXNIP/GPX3/LDHA/AIF1/NCF1/PAGE4/GPX1/KLF2/ANXA1/SOD2/JUN/PARP1/STAT1/HMOX1/CDK1/TRA2B/DHCR24/GPX4/HSPA1A/SOD3/EZH2/IDH1/HSPB1/CTNNB1 24 GO:0051651 maintenance of location in cell 16/320 213/18722 8.45708814612589e-07 4.85342891941558e-05 PTPRC/TMSB4X/TSPO/SRGN/CORO1A/CAV1/CCL3/FTH1/CYBA/SYNE1/SRI/ANXA6/GSTO1/S100A9/VPS13C/GJA1 16 GO:0001906 cell killing 15/320 188/18722 8.72982501066612e-07 4.94132012932499e-05 PTPRC/GAPDH/SERPINB9/HLA-A/HLA-B/TYROBP/LYZ/CORO1A/HLA-DRB1/HLA-DRA/HLA-E/HMGN2/B2M/TUBB/STXBP2 15 GO:0046718 viral entry into host cell 13/320 144/18722 1.17909457483223e-06 6.58380916649564e-05 IFITM2/FCN1/CXCR4/CAV1/HLA-DRB1/ITGB1/CD74/SIVA1/CTSB/CDK1/CTSL/HSPA1A/TFRC 13 GO:0051098 regulation of binding 21/320 363/18722 1.27795566765598e-06 7.04068375833935e-05 TMSB4X/PLAUR/CAV1/C4orf3/ISL1/PHLDA2/CDC42/HMGB1/SRI/STMN1/TGFBR1/JUN/B2M/PARP1/HMOX1/IFIT2/ID1/ACTB/GMNN/CARD16/CTNNB1 21 GO:0001909 leukocyte mediated cytotoxicity 12/320 124/18722 1.45811153890664e-06 7.92752220889767e-05 PTPRC/SERPINB9/HLA-A/HLA-B/TYROBP/CORO1A/HLA-DRB1/HLA-DRA/HLA-E/B2M/TUBB/STXBP2 12 GO:0009410 response to xenobiotic stimulus 24/320 462/18722 1.50479126164397e-06 8.06439453840817e-05 TXNIP/LDHA/CYP2J2/CYBB/APOBEC3A/TSPO/CXCR4/PLIN2/ADIRF/CYBA/GPX1/TIMP2/ANXA1/SOD2/PGF/JUN/PDE4B/B2M/STAT1/HMOX1/CDK1/GSTO1/RHOA/TFRC 24 GO:0009615 response to virus 21/320 367/18722 1.52232036301026e-06 8.06439453840817e-05 PTPRC/IFITM2/FGL2/MX1/IFI44L/APOBEC3A/BST2/CXCR4/ISG15/HTRA1/BNIP3L/SAMHD1/ENO1/PMAIP1/IFNGR2/STMN1/GBP1/STAT1/IFIT2/NPC2/HSPB1 21 GO:1902105 regulation of leukocyte differentiation 18/320 279/18722 1.60749745143072e-06 8.40782211305284e-05 PTPRC/FGL2/HLA-B/EVI2B/TYROBP/HLA-DRB1/HLA-DRA/CCL3/ANXA1/FBN1/HMGB1/ZFP36L2/JUN/CD74/RHOA/CTNNB1/SOX4/CEBPB 18 GO:0022604 regulation of cell morphogenesis 19/320 309/18722 1.68774062066901e-06 8.71718030575545e-05 ALDOA/LST1/ITGB2/FLNA/CORO1A/MYADM/CXCR4/FN1/MSN/CCL3/EZR/FBLN1/ANXA1/CDC42/MYH9/GBP1/MYH10/CAPZB/RHOA 19 GO:0002703 regulation of leukocyte mediated immunity 16/320 226/18722 1.84881302611124e-06 9.43122891838473e-05 PTPRC/SERPINB9/HLA-A/HLA-B/TNFRSF1B/ITGB2/TYROBP/BST2/HLA-DRB1/HLA-DRA/HLA-E/HMGB1/B2M/HMOX1/STXBP2/TFRC 16 GO:0044409 entry into host 13/320 151/18722 2.01689269427934e-06 0.000101631714789783 IFITM2/FCN1/CXCR4/CAV1/HLA-DRB1/ITGB1/CD74/SIVA1/CTSB/CDK1/CTSL/HSPA1A/TFRC 13 GO:0031532 actin cytoskeleton reorganization 11/320 107/18722 2.20683805746485e-06 0.000109863311487286 PLEK/GMFG/FLNA/ARHGDIB/EZR/ANXA1/CDC42/IQGAP2/MYH9/PLEC/RHOA 11 GO:0050678 regulation of epithelial cell proliferation 21/320 381/18722 2.75178140519889e-06 0.000135361437693831 IGF2/CAV1/NRP2/CYBA/HTRA1/GPX1/ZFP36/PGF/ISL1/CDC42/HMGB1/FLT1/TGFBR1/B2M/STAT1/HMOX1/MAGED1/ID1/CTNNB1/PDCD6/GJA1 21 GO:0051017 actin filament bundle assembly 13/320 157/18722 3.11870098130157e-06 0.000151605558291036 AIF1/PLEK/FLNA/MARCKS/LCP1/EZR/ACTG1/CDC42/PFN1/STMN1/TGFBR1/RHOA/ID1 13 GO:0045637 regulation of myeloid cell differentiation 15/320 210/18722 3.48407663634537e-06 0.000167397728620687 EVI2B/TYROBP/HLA-DRB1/CCL3/ISG15/ZFP36/FBN1/HMGB1/JUN/CD74/B2M/STAT1/HSPA1A/CTNNB1/CEBPB 15 GO:2001233 regulation of apoptotic signaling pathway 20/320 356/18722 3.58039810042017e-06 0.000170048332769381 PTPRC/TNFSF10/PLAUR/CAV1/GPX1/ENO1/SOD2/PMAIP1/TIMP3/TGFBR1/PTTG1IP/CD74/PARP1/HMOX1/S100A9/HSPA1A/MAGED1/YBX3/HSPB1/CTNNB1 20 GO:0002468 dendritic cell antigen processing and presentation 5/320 15/18722 3.68894241611983e-06 0.000171891144876348 FGL2/HLA-DRB1/HLA-DRA/CD68/CD74 5 GO:0051235 maintenance of location 19/320 326/18722 3.70239881268029e-06 0.000171891144876348 PTPRC/TMSB4X/TSPO/FLNA/SRGN/CORO1A/CAV1/PLIN2/CCL3/FTH1/CYBA/SYNE1/FBN1/SRI/ANXA6/GSTO1/S100A9/VPS13C/GJA1 19 GO:0001914 regulation of T cell mediated cytotoxicity 7/320 39/18722 3.83800106007531e-06 0.00017620689311368 PTPRC/HLA-A/HLA-B/HLA-DRB1/HLA-DRA/HLA-E/B2M 7 GO:0061572 actin filament bundle organization 13/320 161/18722 4.12255927681577e-06 0.000186539353128176 AIF1/PLEK/FLNA/MARCKS/LCP1/EZR/ACTG1/CDC42/PFN1/STMN1/TGFBR1/RHOA/ID1 13 GO:0006091 generation of precursor metabolites and energy 24/320 490/18722 4.15334474535144e-06 0.000186539353128176 GAPDH/CROT/LDHA/ALDOA/NCF2/CYBB/IGF2/NCF1/PKM/TPI1/CYBA/CYP19A1/ENO1/PYGL/PHLDA2/HMGB1/PLEC/NDUFB1/CDK1/PGK1/UGP2/NDUFB7/RHOA/IDH1 24 GO:0045185 maintenance of protein location 10/320 93/18722 4.26249630709592e-06 0.000188238395843728 TMSB4X/TSPO/FLNA/SRGN/CAV1/SYNE1/FBN1/SRI/VPS13C/GJA1 10 GO:0008064 regulation of actin polymerization or depolymerization 14/320 187/18722 4.28228683671598e-06 0.000188238395843728 TMSB4X/PLEK/GMFG/CORO1A/MYADM/COTL1/CAPG/PFN1/IQGAP2/CAPZA1/CAPZB/VASP/ACTR3/RHOA 14 GO:0070997 neuron death 20/320 361/18722 4.4149162498605e-06 0.000192025620467617 GAPDH/TNFRSF1B/ITGB2/TYROBP/CORO1A/CCL3/GPX1/SOD2/ISL1/CDC42/JUN/REL/NAMPT/PARP1/HMOX1/DHCR24/PPT1/RHOA/CTNNB1/CEBPB 20 GO:0030832 regulation of actin filament length 14/320 188/18722 4.55659867981421e-06 0.000196123601510337 TMSB4X/PLEK/GMFG/CORO1A/MYADM/COTL1/CAPG/PFN1/IQGAP2/CAPZA1/CAPZB/VASP/ACTR3/RHOA 14 GO:0001912 positive regulation of leukocyte mediated cytotoxicity 8/320 56/18722 4.64533083397266e-06 0.000197881515525516 PTPRC/HLA-A/HLA-B/TYROBP/HLA-DRB1/HLA-DRA/HLA-E/B2M 8 GO:0052547 regulation of peptidase activity 23/320 461/18722 4.89074136767198e-06 0.000206209625828782 GAPDH/SERPINB9/SERPINA1/TNFSF10/PSMB9/BST2/PLAUR/LAPTM5/FN1/CAV1/GPX1/TIMP2/FBLN1/SERPINB1/PMAIP1/HMGB1/TIMP3/TFPI2/DHCR24/S100A9/RHOA/CARD16/PDCD6 23 GO:2001242 regulation of intrinsic apoptotic signaling pathway 13/320 164/18722 5.05338901397379e-06 0.000210915185916563 PLAUR/CAV1/GPX1/ENO1/SOD2/PMAIP1/PTTG1IP/CD74/PARP1/S100A9/HSPA1A/YBX3/HSPB1 13 GO:0030041 actin filament polymerization 14/320 190/18722 5.15251519131406e-06 0.000212901927705097 TMSB4X/AIF1/GMFG/CORO1A/MYADM/COTL1/CAPG/PFN1/IQGAP2/CAPZA1/CAPZB/VASP/ACTR3/RHOA 14 GO:0008154 actin polymerization or depolymerization 15/320 217/18722 5.20505996872063e-06 0.00021294364149261 TMSB4X/AIF1/PLEK/GMFG/CORO1A/MYADM/COTL1/CAPG/PFN1/IQGAP2/CAPZA1/CAPZB/VASP/ACTR3/RHOA 15 GO:0050777 negative regulation of immune response 14/320 194/18722 6.55579888512921e-06 0.000265574127385823 PTPRC/SERPINB9/HLA-A/FGL2/HLA-B/HLA-DRB1/ISG15/HTRA1/GPX1/HLA-E/ANXA1/SAMHD1/PARP14/HMOX1 14 GO:0019221 cytokine-mediated signaling pathway 23/320 472/18722 7.19312549317728e-06 0.000288563053765131 PTPRC/TMSB4X/IFITM2/TNFRSF1B/MX1/TNFSF13B/CCL3L3/LAPTM5/CXCR4/FCER1G/CAV1/KRT8/CCL3/ISG15/SAMHD1/PARP14/KRT18/IFNGR2/CD74/STAT1/HSPA1A/CSF2RA/CARD16 23 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 5/320 17/18722 7.39054568043828e-06 0.000293632064918952 HLA-A/HLA-B/HLA-E/HLA-C/B2M 5 GO:0030833 regulation of actin filament polymerization 13/320 171/18722 7.98177683362245e-06 0.0003141019226336 TMSB4X/GMFG/CORO1A/MYADM/COTL1/CAPG/PFN1/IQGAP2/CAPZA1/CAPZB/VASP/ACTR3/RHOA 13 GO:0002181 cytoplasmic translation 12/320 148/18722 9.27120231267339e-06 0.00036140196184874 RPS29/RPL37A/RPS27/PKM/RPS21/RPS17/RPL23/RPL36/RPS28/RPL37/EIF4H/YBX3 12 GO:0031348 negative regulation of defense response 16/320 258/18722 1.00817302276152e-05 0.000389324385986039 PTPRC/SERPINB9/HLA-A/FGL2/HLA-B/TNFRSF1B/HLA-DRB1/ISG15/HTRA1/GPX1/ZFP36/HLA-E/SAMHD1/PARP14/ISL1/PBK 16 GO:0052126 movement in host environment 13/320 175/18722 1.02545977896371e-05 0.000392333315433153 IFITM2/FCN1/CXCR4/CAV1/HLA-DRB1/ITGB1/CD74/SIVA1/CTSB/CDK1/CTSL/HSPA1A/TFRC 13 GO:0030595 leukocyte chemotaxis 15/320 230/18722 1.05037171118555e-05 0.00039817760647878 AIF1/ITGB2/CCL3L3/CORO1A/CXCR4/FCER1G/CCL3/ANXA1/PGF/HMGB1/FLT1/CD74/PLEC/PDE4B/S100A9 15 GO:0001910 regulation of leukocyte mediated cytotoxicity 9/320 82/18722 1.09108141447328e-05 0.000409849854963963 PTPRC/SERPINB9/HLA-A/HLA-B/TYROBP/HLA-DRB1/HLA-DRA/HLA-E/B2M 9 GO:0051701 biological process involved in interaction with host 14/320 203/18722 1.10166537520516e-05 0.000410097417148444 SERPINB9/IFITM2/FCN1/CXCR4/CAV1/HLA-DRB1/ITGB1/CD74/SIVA1/CTSB/CDK1/CTSL/HSPA1A/TFRC 14 GO:0031343 positive regulation of cell killing 8/320 63/18722 1.14177406640681e-05 0.000421233075213654 PTPRC/HLA-A/HLA-B/TYROBP/HLA-DRB1/HLA-DRA/HLA-E/B2M 8 GO:0003012 muscle system process 22/320 452/18722 1.16160293700497e-05 0.000422160835704434 TNFRSF1B/ALDOA/AIF1/FLNA/CXCR4/CAV1/SLC6A8/CYBA/C12orf57/DSP/ENO1/TPM4/ATP2B1/SRI/PDE4B/PARP1/HMOX1/ANXA6/GSTO1/RHOA/EZH2/GJA1 22 GO:0032271 regulation of protein polymerization 15/320 232/18722 1.16472253800352e-05 0.000422160835704434 TMSB4X/GMFG/CORO1A/MYADM/COTL1/CAPG/PFN1/STMN1/IQGAP2/CAPZA1/CAPZB/VASP/HSPA1A/ACTR3/RHOA 15 GO:0036293 response to decreased oxygen levels 18/320 322/18722 1.18105321635618e-05 0.000424357555650759 LDHA/CYBB/CXCR4/CAV1/CYBA/BNIP3L/ENO1/SOD2/BACH1/PGF/PMAIP1/STC2/NAMPT/HMOX1/PGK1/SOD3/RHOA/CARD16 18 GO:0002699 positive regulation of immune effector process 15/320 235/18722 1.35700179788262e-05 0.000479315177562232 PTPRC/HLA-A/HLA-B/ITGB2/TYROBP/LAPTM5/HLA-DRB1/HLA-DRA/HLA-E/ANXA1/CD74/B2M/HMOX1/STXBP2/TFRC 15 GO:0008360 regulation of cell shape 12/320 154/18722 1.38872342479979e-05 0.000479315177562232 ALDOA/LST1/ITGB2/CORO1A/FN1/MSN/CCL3/EZR/ANXA1/MYH9/MYH10/RHOA 12 GO:0001774 microglial cell activation 7/320 47/18722 1.39592257233822e-05 0.000479315177562232 PTPRC/AIF1/ITGB2/TYROBP/CCL3/IFNGR2/NAMPT 7 GO:0051607 defense response to virus 16/320 265/18722 1.4075131912198e-05 0.000479315177562232 PTPRC/IFITM2/FGL2/MX1/IFI44L/APOBEC3A/BST2/ISG15/HTRA1/BNIP3L/SAMHD1/PMAIP1/IFNGR2/GBP1/STAT1/IFIT2 16 GO:0140546 defense response to symbiont 16/320 265/18722 1.4075131912198e-05 0.000479315177562232 PTPRC/IFITM2/FGL2/MX1/IFI44L/APOBEC3A/BST2/ISG15/HTRA1/BNIP3L/SAMHD1/PMAIP1/IFNGR2/GBP1/STAT1/IFIT2 16 GO:0048762 mesenchymal cell differentiation 15/320 236/18722 1.42707868511621e-05 0.000479315177562232 FLNA/FN1/NRP2/EFNB1/ISL1/TGFBR1/SEMA6D/HNRNPAB/STAT1/ANXA6/S100A4/EZH2/CTNNB1/PDCD6/PDCD4 15 GO:0002573 myeloid leukocyte differentiation 14/320 208/18722 1.4511068854751e-05 0.000479315177562232 EVI2B/TYROBP/HLA-DRB1/CCL3/FBN1/CDC42/JUN/CD74/MYH9/PARP1/SNX10/CTNNB1/TFRC/CEBPB 14 GO:0002831 regulation of response to biotic stimulus 18/320 327/18722 1.4540567246663e-05 0.000479315177562232 MNDA/SERPINB9/HLA-A/FGL2/HLA-B/FCN1/NCF1/TYROBP/HLA-DRB1/ISG15/CYBA/HTRA1/HLA-E/SAMHD1/PARP14/HMGB1/STAT1/CARD16 18 GO:0051258 protein polymerization 17/320 296/18722 1.45864808166925e-05 0.000479315177562232 TMSB4X/AIF1/GMFG/CORO1A/MYADM/COTL1/CAPG/PFN1/STMN1/IQGAP2/CAPZA1/CAPZB/GPX4/VASP/HSPA1A/ACTR3/RHOA 17 GO:0002709 regulation of T cell mediated immunity 9/320 85/18722 1.46577434186269e-05 0.000479315177562232 PTPRC/HLA-A/HLA-B/TNFRSF1B/HLA-DRB1/HLA-DRA/HLA-E/HMGB1/B2M 9 GO:0045766 positive regulation of angiogenesis 13/320 181/18722 1.47320976646669e-05 0.000479315177562232 CYBB/PKM/CXCR4/MTDH/ADAM12/PGF/ISL1/HMGB1/ITGB1/FLT1/HMOX1/HSPB1/PDCD6 13 GO:1904018 positive regulation of vasculature development 13/320 181/18722 1.47320976646669e-05 0.000479315177562232 CYBB/PKM/CXCR4/MTDH/ADAM12/PGF/ISL1/HMGB1/ITGB1/FLT1/HMOX1/HSPB1/PDCD6 13 GO:1903131 mononuclear cell differentiation 21/320 426/18722 1.52226571280743e-05 0.00048684585712955 PTPRC/FGL2/HLA-B/TNFSF13B/FCER1G/HLA-DRB1/HLA-DRA/ANXA1/HMGB1/ITGB1/ZFP36L2/JUN/CD74/MYH9/B2M/CTSL/RHOA/EZH2/CTNNB1/SOX4/CEBPB 21 GO:0071222 cellular response to lipopolysaccharide 14/320 209/18722 1.53170284188871e-05 0.00048684585712955 VIM/TNFRSF1B/TSPO/CD68/CCL3/ZFP36/MTDH/LITAF/HMGB1/PDE4B/RHOA/CARD16/PDCD4/CEBPB 14 GO:1902905 positive regulation of supramolecular fiber organization 14/320 209/18722 1.53170284188871e-05 0.00048684585712955 PLEK/GMFG/FLNA/CORO1A/GPX1/CDC42/PFN1/IQGAP2/TGFBR1/VASP/HSPA1A/ACTR3/RHOA/ID1 14 GO:0002832 negative regulation of response to biotic stimulus 10/320 108/18722 1.63014331765335e-05 0.000514179556377378 SERPINB9/HLA-A/FGL2/HLA-B/ISG15/HTRA1/HLA-E/SAMHD1/PARP14/CARD16 10 GO:0002262 myeloid cell homeostasis 12/320 157/18722 1.68702562257787e-05 0.000528090141855437 ISG15/RPS17/KLF2/ZFP36/ANXA1/HMGB1/PDE4B/B2M/STAT1/HMOX1/UBA5/HSPA1A 12 GO:0002237 response to molecule of bacterial origin 19/320 363/18722 1.70648347361377e-05 0.000530164640073091 VIM/TNFRSF1B/TSPO/CD68/CCL3/ZFP36/MTDH/SOD2/LITAF/HMGB1/JUN/PDE4B/B2M/S100A9/RHOA/CARD16/PDCD4/GJA1/CEBPB 19 GO:0001913 T cell mediated cytotoxicity 7/320 49/18722 1.85168055031896e-05 0.000570980898053577 PTPRC/HLA-A/HLA-B/HLA-DRB1/HLA-DRA/HLA-E/B2M 7 GO:0002366 leukocyte activation involved in immune response 16/320 275/18722 2.22149391327938e-05 0.000679941692568177 PTPRC/FGL2/ITGB2/TYROBP/CORO1A/FCER1G/HLA-DRB1/LCP1/HLA-DRA/CCL3/ANXA1/HMGB1/CD74/HMOX1/STXBP2/TFRC 16 GO:0051402 neuron apoptotic process 15/320 246/18722 2.32526747538911e-05 0.000693280792666918 GAPDH/TYROBP/CORO1A/CCL3/GPX1/SOD2/ISL1/CDC42/JUN/PARP1/HMOX1/PPT1/RHOA/CTNNB1/CEBPB 15 GO:0071216 cellular response to biotic stimulus 15/320 246/18722 2.32526747538911e-05 0.000693280792666918 TXNIP/VIM/TNFRSF1B/TSPO/CD68/CCL3/ZFP36/MTDH/LITAF/HMGB1/PDE4B/RHOA/CARD16/PDCD4/CEBPB 15 GO:0001666 response to hypoxia 17/320 307/18722 2.33000886384607e-05 0.000693280792666918 LDHA/CYBB/CXCR4/CAV1/CYBA/BNIP3L/ENO1/SOD2/BACH1/PGF/PMAIP1/STC2/HMOX1/PGK1/SOD3/RHOA/CARD16 17 GO:0007596 blood coagulation 14/320 217/18722 2.33218853293082e-05 0.000693280792666918 SERPINA1/PLEK/FLNA/PLAUR/FN1/FCER1G/CAV1/F5/ACTG1/FBLN1/MYH9/TFPI2/ACTB/HSPB1 14 GO:0010959 regulation of metal ion transport 20/320 406/18722 2.45612747041468e-05 0.000724908479125247 FXYD5/TSPO/FLNA/CORO1A/CXCR4/CAV1/C4orf3/CCL3/CYBA/FXYD3/CD63/ATP2B1/SRI/ITGB1/PDE4B/B2M/GSTO1/RHOA/CTNNB1/GJA1 20 GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response 8/320 70/18722 2.50930775154348e-05 0.000735351746764372 PTPRC/HLA-DMA/HLA-DPA1/HLA-DRB1/HLA-DRA/HLA-DPB1/B2M/TFRC 8 GO:0050792 regulation of viral process 12/320 164/18722 2.60912378676536e-05 0.000759218273726372 IFITM2/MX1/FCN1/APOBEC3A/BST2/CXCR4/HLA-DRB1/ISG15/ZFP36/CD74/STAT1/TOP2A 12 GO:0060326 cell chemotaxis 17/320 310/18722 2.636749104181e-05 0.000760261778164766 TMSB4X/AIF1/ITGB2/CCL3L3/CORO1A/CXCR4/FCER1G/CCL3/ANXA1/PGF/HMGB1/FLT1/CD74/PLEC/PDE4B/S100A9/HSPB1 17 GO:0002263 cell activation involved in immune response 16/320 279/18722 2.64950861703113e-05 0.000760261778164766 PTPRC/FGL2/ITGB2/TYROBP/CORO1A/FCER1G/HLA-DRB1/LCP1/HLA-DRA/CCL3/ANXA1/HMGB1/CD74/HMOX1/STXBP2/TFRC 16 GO:0032496 response to lipopolysaccharide 18/320 343/18722 2.74748208149062e-05 0.000782937652463395 VIM/TNFRSF1B/TSPO/CD68/CCL3/ZFP36/MTDH/SOD2/LITAF/HMGB1/JUN/PDE4B/S100A9/RHOA/CARD16/PDCD4/GJA1/CEBPB 18 GO:0071219 cellular response to molecule of bacterial origin 14/320 221/18722 2.85579060071985e-05 0.000808227860422907 VIM/TNFRSF1B/TSPO/CD68/CCL3/ZFP36/MTDH/LITAF/HMGB1/PDE4B/RHOA/CARD16/PDCD4/CEBPB 14 GO:0031333 negative regulation of protein-containing complex assembly 11/320 140/18722 2.93098621790451e-05 0.000823866330093974 TMSB4X/MYADM/LMO4/CAPG/ISL1/CDC42/HMGB1/PFN1/STMN1/CAPZA1/CAPZB 11 GO:0000302 response to reactive oxygen species 14/320 222/18722 3.00181620037143e-05 0.000826900302662316 TXNIP/LDHA/NCF1/GPX1/KLF2/ANXA1/SOD2/JUN/STAT1/HMOX1/CDK1/TRA2B/SOD3/EZH2 14 GO:0007599 hemostasis 14/320 222/18722 3.00181620037143e-05 0.000826900302662316 SERPINA1/PLEK/FLNA/PLAUR/FN1/FCER1G/CAV1/F5/ACTG1/FBLN1/MYH9/TFPI2/ACTB/HSPB1 14 GO:0050817 coagulation 14/320 222/18722 3.00181620037143e-05 0.000826900302662316 SERPINA1/PLEK/FLNA/PLAUR/FN1/FCER1G/CAV1/F5/ACTG1/FBLN1/MYH9/TFPI2/ACTB/HSPB1 14 GO:0070482 response to oxygen levels 18/320 347/18722 3.20009930231959e-05 0.000875682802462552 LDHA/CYBB/CXCR4/CAV1/CYBA/BNIP3L/ENO1/SOD2/BACH1/PGF/PMAIP1/STC2/NAMPT/HMOX1/PGK1/SOD3/RHOA/CARD16 18 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 12/320 168/18722 3.31198026864185e-05 0.000897466416615681 PTPRC/HLA-A/HLA-B/TNFRSF1B/TNFSF13B/HLA-DRB1/HLA-DRA/HLA-E/ANXA1/HMGB1/B2M/TFRC 12 GO:1901342 regulation of vasculature development 18/320 348/18722 3.32314525029524e-05 0.000897466416615681 CYBB/PKM/CXCR4/KLF2/MTDH/ADAM12/PGF/ISL1/HMGB1/ITGB1/FLT1/STAT1/HMOX1/PGK1/ID1/HSPB1/CTNNB1/PDCD6 18 GO:0031032 actomyosin structure organization 13/320 196/18722 3.41619354820671e-05 0.00091660465851884 KRT19/KRT8/ACTG1/CDC42/PFN1/ITGB1/STMN1/TGFBR1/MYH9/PLEC/MYH10/FRMD6/RHOA 13 GO:0034284 response to monosaccharide 14/320 225/18722 3.4799897963834e-05 0.000927697925074593 TXNIP/LDHA/HLA-DRB1/CYBA/DYNLL1/SOD2/KRT18/SRI/HMGN3/NAMPT/TRA2B/RHOA/SOX4/GJA1 14 GO:0051101 regulation of DNA binding 10/320 118/18722 3.5302480116483e-05 0.00093506312718787 TMSB4X/PLAUR/ISL1/HMGB1/SRI/JUN/PARP1/HMOX1/ID1/CTNNB1 10 GO:0002449 lymphocyte mediated immunity 18/320 350/18722 3.58194045167486e-05 0.000942711971103219 PTPRC/SERPINB9/HLA-A/HLA-B/TNFRSF1B/HLA-DMA/CORO1A/HLA-DPA1/FCER1G/HLA-DRB1/HLA-DRA/HLA-DPB1/HLA-E/HMGB1/CD74/B2M/TUBB/TFRC 18 GO:0042692 muscle cell differentiation 19/320 384/18722 3.69236464789833e-05 0.00096562346361493 KRT19/IGF2/CD53/KRT8/GPX1/ACTG1/SYNE1/SOD2/ADAM12/ISL1/ITGB1/MYH9/MORF4L2/PLEC/CDK1/BHLHE41/EZH2/CTNNB1/PDCD4 19 GO:0006801 superoxide metabolic process 8/320 74/18722 3.77610610008555e-05 0.000977092666918657 NCF2/CYBB/ITGB2/NCF1/TYROBP/CYBA/SOD2/SOD3 8 GO:1901214 regulation of neuron death 17/320 319/18722 3.78351468313129e-05 0.000977092666918657 TNFRSF1B/ITGB2/TYROBP/CORO1A/CCL3/SOD2/ISL1/CDC42/JUN/REL/PARP1/HMOX1/DHCR24/PPT1/RHOA/CTNNB1/CEBPB 17 GO:0034599 cellular response to oxidative stress 16/320 288/18722 3.88952636785074e-05 0.000992069318022177 AIF1/NCF1/PAGE4/GPX1/KLF2/ANXA1/SOD2/JUN/PARP1/HMOX1/CDK1/HSPA1A/SOD3/EZH2/HSPB1/CTNNB1 16 GO:0097193 intrinsic apoptotic signaling pathway 16/320 288/18722 3.88952636785074e-05 0.000992069318022177 TNFRSF1B/PLAUR/CAV1/GPX1/ENO1/SOD2/PMAIP1/PTTG1IP/CD74/PARP1/HMOX1/S100A9/HSPA1A/YBX3/HSPB1/CEBPB 16 GO:0032102 negative regulation of response to external stimulus 20/320 420/18722 3.96294055042374e-05 0.00100459327327306 PTPRC/SERPINB9/HLA-A/FGL2/HLA-B/TNFRSF1B/AIF1/HLA-DRB1/ISG15/HTRA1/GPX1/ZFP36/HLA-E/SAMHD1/PARP14/ISL1/SEMA6D/PBK/CARD16/GJA1 20 GO:0042542 response to hydrogen peroxide 11/320 146/18722 4.32029059436876e-05 0.00108850248389828 TXNIP/LDHA/GPX1/KLF2/ANXA1/SOD2/JUN/STAT1/HMOX1/CDK1/EZH2 11 GO:0002711 positive regulation of T cell mediated immunity 7/320 56/18722 4.51335555882956e-05 0.00112602416568286 PTPRC/HLA-A/HLA-B/HLA-DRB1/HLA-DRA/HLA-E/B2M 7 GO:0048608 reproductive structure development 20/320 424/18722 4.52371760656714e-05 0.00112602416568286 KRT19/TNFSF10/IGF2/FLNA/KRT8/HTRA1/ANXA1/CYP19A1/STC2/PHLDA2/TGFBR1/PSAP/CTSB/DHCR24/LRP2/IDH1/YBX3/CTNNB1/GJA1/CEBPB 20 GO:0001911 negative regulation of leukocyte mediated cytotoxicity 5/320 24/18722 4.6010622803234e-05 0.0011349712315942 PTPRC/SERPINB9/HLA-A/HLA-B/HLA-E 5 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 9/320 98/18722 4.61459745662694e-05 0.0011349712315942 PLAUR/GPX1/ENO1/SOD2/PTTG1IP/CD74/HSPA1A/YBX3/HSPB1 9 GO:0042176 regulation of protein catabolic process 19/320 391/18722 4.71136901447011e-05 0.00115191578507636 TNFRSF1B/FLNA/LAPTM5/CAV1/MSN/EZR/RPL23/GPX1/TIMP2/OAZ1/TIMP3/DDA1/PTTG1IP/PSMD1/HSPA1A/PBK/LRP2/AZIN1/GJA1 19 GO:0061458 reproductive system development 20/320 427/18722 4.98968455700072e-05 0.0012013943321774 KRT19/TNFSF10/IGF2/FLNA/KRT8/HTRA1/ANXA1/CYP19A1/STC2/PHLDA2/TGFBR1/PSAP/CTSB/DHCR24/LRP2/IDH1/YBX3/CTNNB1/GJA1/CEBPB 20 GO:0031341 regulation of cell killing 9/320 99/18722 5.00096382222924e-05 0.0012013943321774 PTPRC/SERPINB9/HLA-A/HLA-B/TYROBP/HLA-DRB1/HLA-DRA/HLA-E/B2M 9 GO:0033209 tumor necrosis factor-mediated signaling pathway 9/320 99/18722 5.00096382222924e-05 0.0012013943321774 TMSB4X/TNFRSF1B/TNFSF13B/LAPTM5/KRT8/KRT18/STAT1/HSPA1A/CARD16 9 GO:0052548 regulation of endopeptidase activity 20/320 432/18722 5.8619754758162e-05 0.00140009726393483 GAPDH/SERPINB9/SERPINA1/TNFSF10/PSMB9/BST2/PLAUR/LAPTM5/GPX1/TIMP2/SERPINB1/PMAIP1/HMGB1/TIMP3/TFPI2/DHCR24/S100A9/RHOA/CARD16/PDCD6 20 GO:0031334 positive regulation of protein-containing complex assembly 14/320 237/18722 6.12654764575716e-05 0.00145302228770127 PLEK/GMFG/CORO1A/LCP1/MSN/ISG15/ICE1/PFN1/IQGAP2/VASP/HSPA1A/ACTR3/RHOA/TFRC 14 GO:0001936 regulation of endothelial cell proliferation 12/320 179/18722 6.15389400647922e-05 0.00145302228770127 IGF2/CAV1/NRP2/CYBA/PGF/HMGB1/FLT1/TGFBR1/STAT1/HMOX1/PDCD6/GJA1 12 GO:0048660 regulation of smooth muscle cell proliferation 12/320 180/18722 6.49428671136106e-05 0.00152468140291727 AIF1/CYBA/SOD2/IGFBP3/JUN/NAMPT/STAT1/HMOX1/RHOA/CTNNB1/PDCD4/GJA1 12 GO:0072593 reactive oxygen species metabolic process 14/320 239/18722 6.70669994479793e-05 0.00156395352710869 GPX3/NCF2/CYBB/ITGB2/NCF1/TSPO/TYROBP/PAGE4/CYBA/GPX1/SOD2/PMAIP1/SOD3/RHOA 14 GO:0032760 positive regulation of tumor necrosis factor production 9/320 103/18722 6.83110193364639e-05 0.00156395352710869 PTPRC/CYBB/TYROBP/CCL3/CYBA/HLA-E/ISL1/HMGB1/HSPB1 9 GO:0045639 positive regulation of myeloid cell differentiation 9/320 103/18722 6.83110193364639e-05 0.00156395352710869 EVI2B/TYROBP/HLA-DRB1/ISG15/HMGB1/JUN/CD74/STAT1/HSPA1A 9 GO:0032640 tumor necrosis factor production 12/320 181/18722 6.85081288496304e-05 0.00156395352710869 PTPRC/CYBB/TSPO/TYROBP/CCL3/CYBA/ZFP36/HLA-E/ISL1/HMGB1/UBE2J1/HSPB1 12 GO:0032680 regulation of tumor necrosis factor production 12/320 181/18722 6.85081288496304e-05 0.00156395352710869 PTPRC/CYBB/TSPO/TYROBP/CCL3/CYBA/ZFP36/HLA-E/ISL1/HMGB1/UBE2J1/HSPB1 12 GO:0051222 positive regulation of protein transport 16/320 303/18722 7.11426989791311e-05 0.00161517380319654 ITGB2/FLNA/HLA-DRB1/EZR/WLS/DYNLL1/OAZ1/ISL1/CDC42/ICE1/SRI/TCAF1/MYH10/CDK1/SOX4/GJA1 16 GO:0051764 actin crosslink formation 4/320 14/18722 7.32283272088163e-05 0.00165343960670398 AIF1/FLNA/MARCKS/LCP1 4 GO:0002819 regulation of adaptive immune response 12/320 183/18722 7.61480486948471e-05 0.0017100203109082 PTPRC/HLA-A/HLA-B/TNFRSF1B/TNFSF13B/HLA-DRB1/HLA-DRA/HLA-E/ANXA1/HMGB1/B2M/TFRC 12 GO:0043523 regulation of neuron apoptotic process 13/320 212/18722 7.66405825014988e-05 0.00171177776700645 TYROBP/CORO1A/CCL3/SOD2/ISL1/CDC42/JUN/PARP1/HMOX1/PPT1/RHOA/CTNNB1/CEBPB 13 GO:0032231 regulation of actin filament bundle assembly 9/320 105/18722 7.93932268517616e-05 0.00176372480296494 PLEK/FLNA/ACTG1/CDC42/PFN1/STMN1/TGFBR1/RHOA/ID1 9 GO:0048659 smooth muscle cell proliferation 12/320 184/18722 8.02358778717039e-05 0.00176523074512467 AIF1/CYBA/SOD2/IGFBP3/JUN/NAMPT/STAT1/HMOX1/RHOA/CTNNB1/PDCD4/GJA1 12 GO:0048545 response to steroid hormone 17/320 339/18722 8.03154356445882e-05 0.00176523074512467 TXNIP/AIF1/CYBB/TSPO/CAV1/CYBA/LBH/ZFP36/ANXA1/ISL1/ATP2B1/HMGB1/ZFP36L2/PARP1/UBA5/RHOA/IDH1 17 GO:1902107 positive regulation of leukocyte differentiation 11/320 157/18722 8.36509834763228e-05 0.00181270235096873 PTPRC/EVI2B/TYROBP/HLA-DRB1/HLA-DRA/ANXA1/HMGB1/JUN/CD74/RHOA/SOX4 11 GO:1903708 positive regulation of hemopoiesis 11/320 157/18722 8.36509834763228e-05 0.00181270235096873 PTPRC/EVI2B/TYROBP/HLA-DRB1/HLA-DRA/ANXA1/HMGB1/JUN/CD74/RHOA/SOX4 11 GO:0032703 negative regulation of interleukin-2 production 5/320 27/18722 8.37914203860185e-05 0.00181270235096873 PTPRC/LAPTM5/EZR/ZFP36/GBP1 5 GO:0042116 macrophage activation 9/320 106/18722 8.54774335112602e-05 0.00183954560035691 PTPRC/AIF1/ITGB2/TYROBP/CCL3/HMGB1/IFNGR2/CD74/NAMPT 9 GO:0002440 production of molecular mediator of immune response 16/320 308/18722 8.61944864366849e-05 0.00184536589614706 PTPRC/HLA-A/TNFRSF1B/HLA-DMA/BST2/HLA-DPA1/LAPTM5/HLA-DRB1/HLA-DRA/HLA-DPB1/HLA-E/SAMHD1/CD74/B2M/HMOX1/TFRC 16 GO:0032623 interleukin-2 production 7/320 62/18722 8.76893332908185e-05 0.00185811448798801 PTPRC/LAPTM5/EZR/ZFP36/ANXA1/PDE4B/GBP1 7 GO:0032663 regulation of interleukin-2 production 7/320 62/18722 8.76893332908185e-05 0.00185811448798801 PTPRC/LAPTM5/EZR/ZFP36/ANXA1/PDE4B/GBP1 7 GO:0071706 tumor necrosis factor superfamily cytokine production 12/320 186/18722 8.89816648632926e-05 0.00186606870046659 PTPRC/CYBB/TSPO/TYROBP/CCL3/CYBA/ZFP36/HLA-E/ISL1/HMGB1/UBE2J1/HSPB1 12 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 12/320 186/18722 8.89816648632926e-05 0.00186606870046659 PTPRC/CYBB/TSPO/TYROBP/CCL3/CYBA/ZFP36/HLA-E/ISL1/HMGB1/UBE2J1/HSPB1 12 GO:0045765 regulation of angiogenesis 17/320 342/18722 8.94195553466565e-05 0.00186606870046659 CYBB/PKM/CXCR4/KLF2/MTDH/ADAM12/PGF/ISL1/HMGB1/ITGB1/FLT1/STAT1/HMOX1/PGK1/HSPB1/CTNNB1/PDCD6 17 GO:0046034 ATP metabolic process 15/320 277/18722 9.02024137796943e-05 0.00187294660169697 GAPDH/TMSB4X/LDHA/ALDOA/TSPO/PKM/TPI1/ENO1/NDUFB1/PARP1/CDK1/PGK1/HSPA1A/NDUFB7/RHOA 15 GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 9/320 107/18722 9.19483695875478e-05 0.00188084486700865 PTPRC/HLA-A/HLA-B/TNFSF13B/HLA-DRB1/HLA-DRA/HLA-E/B2M/TFRC 9 GO:0008637 apoptotic mitochondrial changes 9/320 107/18722 9.19483695875478e-05 0.00188084486700865 TNFSF10/PLAUR/GPX1/BNIP3L/SOD2/PMAIP1/JUN/IFIT2/HSPA1A 9 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 9/320 107/18722 9.19483695875478e-05 0.00188084486700865 PTPRC/CYBB/TYROBP/CCL3/CYBA/HLA-E/ISL1/HMGB1/HSPB1 9 GO:0002695 negative regulation of leukocyte activation 12/320 187/18722 9.36539788420364e-05 0.00190629675160244 PTPRC/MNDA/FGL2/LST1/TYROBP/LAPTM5/HLA-DRB1/ANXA1/HMGB1/CD74/HMOX1/CEBPB 12 GO:0042554 superoxide anion generation 6/320 44/18722 9.71752822188102e-05 0.00195012913956009 NCF2/CYBB/ITGB2/NCF1/TYROBP/CYBA 6 GO:0002704 negative regulation of leukocyte mediated immunity 7/320 63/18722 9.72232823691622e-05 0.00195012913956009 PTPRC/SERPINB9/HLA-A/HLA-B/BST2/HLA-E/HMOX1 7 GO:0032233 positive regulation of actin filament bundle assembly 7/320 63/18722 9.72232823691622e-05 0.00195012913956009 PLEK/FLNA/CDC42/PFN1/TGFBR1/RHOA/ID1 7 GO:0043542 endothelial cell migration 15/320 279/18722 9.7730410023124e-05 0.00195083117978526 TMSB4X/NRP2/GPX1/ANXA1/S100P/HMGB1/ITGB1/TGFBR1/MYH9/HMOX1/PLPP3/RHOA/ID1/HSPB1/PDCD6 15 GO:0050878 regulation of body fluid levels 18/320 379/18722 9.94934956797138e-05 0.00196742096411977 SERPINA1/PLEK/FLNA/PLAUR/FN1/FCER1G/CAV1/F5/CYBA/ACTG1/FBLN1/STMN1/MYH9/PLEC/TFPI2/ACTB/HSPB1/GJA1 18 GO:0033002 muscle cell proliferation 14/320 248/18722 9.95137902955062e-05 0.00196742096411977 AIF1/CYBA/SOD2/TGFBR1/IGFBP3/JUN/NAMPT/STAT1/HMOX1/CDK1/RHOA/CTNNB1/PDCD4/GJA1 14 GO:0031342 negative regulation of cell killing 5/320 28/18722 0.00010058810394022 0.00197919069276661 PTPRC/SERPINB9/HLA-A/HLA-B/HLA-E 5 GO:0002705 positive regulation of leukocyte mediated immunity 10/320 134/18722 0.000103899999753396 0.00203466729374897 PTPRC/HLA-A/HLA-B/ITGB2/TYROBP/HLA-DRB1/HLA-DRA/HLA-E/B2M/TFRC 10 GO:0002456 T cell mediated immunity 9/320 109/18722 0.000106128425760594 0.00205451739967644 PTPRC/HLA-A/HLA-B/TNFRSF1B/HLA-DRB1/HLA-DRA/HLA-E/HMGB1/B2M 9 GO:0009746 response to hexose 13/320 219/18722 0.000106405305791568 0.00205451739967644 TXNIP/LDHA/HLA-DRB1/CYBA/DYNLL1/KRT18/SRI/HMGN3/NAMPT/TRA2B/RHOA/SOX4/GJA1 13 GO:0097191 extrinsic apoptotic signaling pathway 13/320 219/18722 0.000106405305791568 0.00205451739967644 PTPRC/TNFRSF1B/TNFSF10/CAV1/KRT8/GPX1/PMAIP1/KRT18/TIMP3/TGFBR1/SIVA1/HMOX1/HSPA1A 13 GO:0030888 regulation of B cell proliferation 7/320 64/18722 0.000107584040760392 0.00205804285380528 PTPRC/MNDA/TNFSF13B/TYROBP/CD74/SLC39A10/TFRC 7 GO:0032507 maintenance of protein location in cell 7/320 64/18722 0.000107584040760392 0.00205804285380528 TMSB4X/TSPO/SRGN/CAV1/SYNE1/VPS13C/GJA1 7 GO:0032535 regulation of cellular component size 18/320 382/18722 0.000109857629664701 0.00209185127085044 TMSB4X/PLEK/GMFG/CORO1A/MYADM/COTL1/FN1/MSN/EZR/CAPG/PFN1/IQGAP2/SEMA6D/CAPZA1/CAPZB/VASP/ACTR3/RHOA 18 GO:0051100 negative regulation of binding 11/320 162/18722 0.000110768465657414 0.00209195716554264 TMSB4X/CAV1/C4orf3/SRI/JUN/B2M/HMOX1/IFIT2/ID1/ACTB/CARD16 11 GO:0048864 stem cell development 8/320 86/18722 0.000111362115911718 0.00209195716554264 PTPRC/FN1/NRP2/EFNB1/ISL1/SEMA6D/ANXA6/PDCD6 8 GO:0097529 myeloid leukocyte migration 13/320 220/18722 0.000111382036887556 0.00209195716554264 AIF1/ITGB2/CCL3L3/FCER1G/CCL3/ANXA1/PGF/CD99/HMGB1/FLT1/CD74/PDE4B/S100A9 13 GO:0002698 negative regulation of immune effector process 9/320 110/18722 0.000113878257666047 0.00212916271799143 PTPRC/SERPINB9/HLA-A/FGL2/HLA-B/BST2/HLA-E/ANXA1/HMOX1 9 GO:0051146 striated muscle cell differentiation 15/320 283/18722 0.000114447067321347 0.00213015892870184 KRT19/IGF2/CD53/KRT8/GPX1/ACTG1/ADAM12/ISL1/ITGB1/MYH9/MORF4L2/PLEC/CDK1/BHLHE41/EZH2 15 GO:0003158 endothelium development 10/320 136/18722 0.00011754133305278 0.00217794075414388 MYADM/CXCR4/MSN/EZR/GPX1/CLIC4/RHOA/ID1/CTNNB1/GJA1 10 GO:0001776 leukocyte homeostasis 8/320 87/18722 0.000120844584591131 0.00222915099790425 TSC22D3/TNFSF13B/CORO1A/ANXA1/PMAIP1/HMGB1/CD74/PDE4B 8 GO:0009743 response to carbohydrate 14/320 253/18722 0.000122860235296572 0.00225625996553527 TXNIP/LDHA/HLA-DRB1/CYBA/DYNLL1/SOD2/KRT18/SRI/HMGN3/NAMPT/TRA2B/RHOA/SOX4/GJA1 14 GO:0001935 endothelial cell proliferation 12/320 193/18722 0.00012636483897791 0.00231035183476428 IGF2/CAV1/NRP2/CYBA/PGF/HMGB1/FLT1/TGFBR1/STAT1/HMOX1/PDCD6/GJA1 12 GO:1904951 positive regulation of establishment of protein localization 16/320 319/18722 0.00012947425526637 0.00233975971168482 ITGB2/FLNA/HLA-DRB1/EZR/WLS/DYNLL1/OAZ1/ISL1/CDC42/ICE1/SRI/TCAF1/MYH10/CDK1/SOX4/GJA1 16 GO:0099010 modification of postsynaptic structure 4/320 16/18722 0.000129590249162583 0.00233975971168482 CDC42/PFN1/MYH10/RHOA 4 GO:0002821 positive regulation of adaptive immune response 9/320 112/18722 0.000130804572458662 0.00233975971168482 PTPRC/HLA-A/HLA-B/TNFSF13B/HLA-DRB1/HLA-DRA/HLA-E/B2M/TFRC 9 GO:0032609 interferon-gamma production 9/320 112/18722 0.000130804572458662 0.00233975971168482 HLA-A/HLA-DPA1/LAPTM5/HLA-DRB1/ISG15/HLA-DPB1/ISL1/HMGB1/PDE4B 9 GO:0032649 regulation of interferon-gamma production 9/320 112/18722 0.000130804572458662 0.00233975971168482 HLA-A/HLA-DPA1/LAPTM5/HLA-DRB1/ISG15/HLA-DPB1/ISL1/HMGB1/PDE4B 9 GO:0051924 regulation of calcium ion transport 14/320 255/18722 0.00013345002502113 0.00237679096287633 TSPO/CORO1A/CXCR4/CAV1/C4orf3/CCL3/CYBA/ATP2B1/SRI/PDE4B/GSTO1/RHOA/CTNNB1/GJA1 14 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 6/320 47/18722 0.000141594815091436 0.00251102908136401 KLF2/BACH1/JUN/HMOX1/HSPA1A/CEBPB 6 GO:0046635 positive regulation of alpha-beta T cell activation 7/320 67/18722 0.000144169999807556 0.00251540373046813 PTPRC/HLA-A/HLA-DRB1/HLA-DRA/HLA-E/ANXA1/RHOA 7 GO:0070527 platelet aggregation 7/320 67/18722 0.000144169999807556 0.00251540373046813 PLEK/FLNA/FN1/ACTG1/MYH9/ACTB/HSPB1 7 GO:0030217 T cell differentiation 14/320 257/18722 0.000144821649669921 0.00251540373046813 PTPRC/FGL2/FCER1G/HLA-DRB1/HLA-DRA/ANXA1/HMGB1/ZFP36L2/CD74/B2M/CTSL/RHOA/CTNNB1/SOX4 14 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 17/320 356/18722 0.00014500109585947 0.00251540373046813 PTPRC/HLA-A/HLA-B/TNFRSF1B/TNFSF13B/HLA-DMA/HLA-DPA1/FCER1G/HLA-DRB1/HLA-DRA/HLA-DPB1/HLA-E/ANXA1/HMGB1/CD74/B2M/TFRC 17 GO:0031960 response to corticosteroid 11/320 167/18722 0.00014505231372062 0.00251540373046813 AIF1/CYBB/CYBA/ZFP36/ANXA1/ISL1/ATP2B1/HMGB1/ZFP36L2/PARP1/RHOA 11 GO:0051495 positive regulation of cytoskeleton organization 13/320 226/18722 0.000145674962799643 0.00251540373046813 PLEK/GMFG/FLNA/CORO1A/CDC42/PFN1/IQGAP2/TGFBR1/VASP/HSPA1A/ACTR3/RHOA/ID1 13 GO:0071674 mononuclear cell migration 12/320 196/18722 0.000146102830424093 0.00251540373046813 AIF1/CCL3L3/CXCR4/MSN/CCL3/ANXA1/CD99/CDC42/HMGB1/FLT1/PLEC/RHOA 12 GO:0010631 epithelial cell migration 17/320 357/18722 0.000149933794181107 0.00257064911849101 TMSB4X/ZEB2/NRP2/GPX1/ANXA1/S100P/HMGB1/PFN1/ITGB1/TGFBR1/MYH9/HMOX1/PLPP3/RHOA/ID1/HSPB1/PDCD6 17 GO:0002706 regulation of lymphocyte mediated immunity 11/320 168/18722 0.000152894718952316 0.0026105825566569 PTPRC/SERPINB9/HLA-A/HLA-B/TNFRSF1B/HLA-DRB1/HLA-DRA/HLA-E/HMGB1/B2M/TFRC 11 GO:0060485 mesenchyme development 15/320 291/18722 0.000155489840084695 0.00264396715732494 FLNA/FN1/NRP2/EFNB1/ISL1/TGFBR1/SEMA6D/HNRNPAB/STAT1/ANXA6/S100A4/EZH2/CTNNB1/PDCD6/PDCD4 15 GO:0046686 response to cadmium ion 7/320 68/18722 0.00015839167156708 0.00268227207752121 CYBB/NCF1/SOD2/JUN/B2M/HMOX1/CDK1 7 GO:0031099 regeneration 12/320 198/18722 0.000160679998722177 0.00270991736620423 TSPO/FLNA/LCP1/GPX1/ANXA1/PGF/ISL1/NREP/HMOX1/CDK1/EZH2/CEBPB 12 GO:0090132 epithelium migration 17/320 360/18722 0.000165624008788294 0.00278194473298061 TMSB4X/ZEB2/NRP2/GPX1/ANXA1/S100P/HMGB1/PFN1/ITGB1/TGFBR1/MYH9/HMOX1/PLPP3/RHOA/ID1/HSPB1/PDCD6 17 GO:0045216 cell-cell junction organization 12/320 200/18722 0.000176483557030635 0.00295234841154082 FLNA/CAV1/ACTG1/MTDH/DSP/CDC42/TGFBR1/PLEC/RHOA/ACTB/CTNNB1/GJA1 12 GO:0048525 negative regulation of viral process 8/320 92/18722 0.000178826210542227 0.00297947541113097 IFITM2/MX1/FCN1/APOBEC3A/BST2/ISG15/ZFP36/STAT1 8 GO:0031589 cell-substrate adhesion 17/320 363/18722 0.000182731234443237 0.00303231108722673 ITGB2/FLNA/CORO1A/MYADM/PLEKHA2/FN1/CCDC80/ACTG1/FBLN1/CD63/CDC42/ITGB1/GBP1/PTPRA/RHOA/ID1/CTNNB1 17 GO:0035456 response to interferon-beta 5/320 32/18722 0.000194886063282832 0.00320971681384217 MNDA/IFITM2/XAF1/BST2/STAT1 5 GO:0090130 tissue migration 17/320 365/18722 0.000194975537336492 0.00320971681384217 TMSB4X/ZEB2/NRP2/GPX1/ANXA1/S100P/HMGB1/PFN1/ITGB1/TGFBR1/MYH9/HMOX1/PLPP3/RHOA/ID1/HSPB1/PDCD6 17 GO:0045824 negative regulation of innate immune response 7/320 71/18722 0.000208003034564769 0.00341058943976835 SERPINB9/HLA-A/HLA-B/ISG15/HLA-E/SAMHD1/PARP14 7 GO:0002283 neutrophil activation involved in immune response 4/320 18/18722 0.00021207586563762 0.00344999006619939 ITGB2/TYROBP/FCER1G/STXBP2 4 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 4/320 18/18722 0.00021207586563762 0.00344999006619939 SERPINB9/HLA-A/HLA-B/HLA-E 4 GO:2000116 regulation of cysteine-type endopeptidase activity 13/320 235/18722 0.000214022428261089 0.00346800264146987 SERPINB9/TNFSF10/PSMB9/PLAUR/LAPTM5/GPX1/PMAIP1/HMGB1/DHCR24/S100A9/RHOA/CARD16/PDCD6 13 GO:0002761 regulation of myeloid leukocyte differentiation 9/320 120/18722 0.000221021096505936 0.00356741863579112 EVI2B/TYROBP/HLA-DRB1/CCL3/FBN1/JUN/CD74/CTNNB1/CEBPB 9 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 8/320 95/18722 0.000223432836552291 0.00359231315421816 TSPO/CAV1/ISG15/RPL23/RPL37/HSPA1A/CTNNB1/SOX4 8 GO:1903036 positive regulation of response to wounding 7/320 72/18722 0.0002270770110525 0.00363675275065476 FLNA/CXCR4/ACTG1/ANXA1/HMGB1/ITGB1/PLPP3 7 GO:0048863 stem cell differentiation 12/320 206/18722 0.000232102984952708 0.0037028939529907 PTPRC/FN1/NRP2/EFNB1/LBH/KRT18/ISL1/ZFP36L2/SEMA6D/ANXA6/CTNNB1/PDCD6 12 GO:0002718 regulation of cytokine production involved in immune response 8/320 96/18722 0.000240183974553966 0.00381707762637303 HLA-A/TNFRSF1B/BST2/LAPTM5/HLA-E/CD74/B2M/HMOX1 8 GO:0071453 cellular response to oxygen levels 11/320 177/18722 0.000241206416061862 0.00381863950638932 CYBB/CAV1/BNIP3L/ENO1/BACH1/PMAIP1/STC2/NAMPT/HMOX1/PGK1/CARD16 11 GO:0050679 positive regulation of epithelial cell proliferation 12/320 207/18722 0.000242689159612154 0.00382744888365427 IGF2/NRP2/CYBA/HTRA1/PGF/CDC42/HMGB1/TGFBR1/HMOX1/ID1/CTNNB1/PDCD6 12 GO:1901216 positive regulation of neuron death 8/320 97/18722 0.000257949953951388 0.00405265859211838 ITGB2/TYROBP/CCL3/CDC42/JUN/PARP1/RHOA/CTNNB1 8 GO:0030098 lymphocyte differentiation 17/320 374/18722 0.000259366659342165 0.00405948119849177 PTPRC/FGL2/TNFSF13B/FCER1G/HLA-DRB1/HLA-DRA/ANXA1/HMGB1/ITGB1/ZFP36L2/CD74/B2M/CTSL/RHOA/EZH2/CTNNB1/SOX4 17 GO:0001959 regulation of cytokine-mediated signaling pathway 10/320 150/18722 0.000262256560660861 0.00408922305151199 PTPRC/LAPTM5/CXCR4/CAV1/ISG15/SAMHD1/PARP14/CD74/HSPA1A/CARD16 10 GO:0002716 negative regulation of natural killer cell mediated immunity 4/320 19/18722 0.000265028713802422 0.00410257399566864 SERPINB9/HLA-A/HLA-B/HLA-E 4 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 12/320 209/18722 0.000265098561675588 0.00410257399566864 SERPINB9/TNFSF10/PLAUR/LAPTM5/GPX1/PMAIP1/HMGB1/DHCR24/S100A9/RHOA/CARD16/PDCD6 12 GO:0060047 heart contraction 13/320 241/18722 0.000273508802137881 0.00421693421803629 CYP2J2/FLNA/CXCR4/CAV1/GPX1/DSP/ISL1/ATP2B1/CDC42/SRI/PDE4B/GSTO1/GJA1 13 GO:0002367 cytokine production involved in immune response 8/320 98/18722 0.000276776974341175 0.00422056944703521 HLA-A/TNFRSF1B/BST2/LAPTM5/HLA-E/CD74/B2M/HMOX1 8 GO:0031396 regulation of protein ubiquitination 12/320 210/18722 0.000276947361725942 0.00422056944703521 TSPO/LAPTM5/CAV1/ISG15/RPL23/RPL37/ARRDC3/TGFBR1/PTTG1IP/HSPA1A/SOX4/PDCD6 12 GO:0050866 negative regulation of cell activation 12/320 210/18722 0.000276947361725942 0.00422056944703521 PTPRC/MNDA/FGL2/LST1/TYROBP/LAPTM5/HLA-DRB1/ANXA1/HMGB1/CD74/HMOX1/CEBPB 12 GO:0043620 regulation of DNA-templated transcription in response to stress 6/320 53/18722 0.000277830321779665 0.00422056944703521 KLF2/BACH1/JUN/HMOX1/HSPA1A/CEBPB 6 GO:1903320 regulation of protein modification by small protein conjugation or removal 13/320 242/18722 0.000284683217726822 0.0043088317056675 TSPO/LAPTM5/CAV1/ISG15/RPL23/RPL37/ARRDC3/TGFBR1/PTTG1IP/HSPA1A/CTNNB1/SOX4/PDCD6 13 GO:0006968 cellular defense response 6/320 54/18722 0.000308123272159309 0.00464658890716155 MNDA/NCF2/LSP1/NCF1/TYROBP/ITGB1 6 GO:0034765 regulation of ion transmembrane transport 20/320 491/18722 0.000322942895937884 0.00485236380369213 TMSB4X/CTSS/FXYD5/CYBB/FLNA/CLIC3/CORO1A/CAV1/C4orf3/CYBA/FXYD3/CD63/SRI/ITGB1/IFNGR2/CLIC4/SLC43A2/TCAF1/PDE4B/GSTO1 20 GO:0022898 regulation of transmembrane transporter activity 14/320 278/18722 0.000324743254221998 0.00486173596538151 TMSB4X/CTSS/FXYD5/CAV1/C4orf3/FXYD3/SRI/ITGB1/IFNGR2/TCAF1/PDE4B/GSTO1/ACTB/GJA1 14 GO:0006936 muscle contraction 16/320 347/18722 0.000334447654778175 0.00498894479979574 ALDOA/FLNA/CXCR4/CAV1/SLC6A8/C12orf57/DSP/ENO1/TPM4/ATP2B1/SRI/PDE4B/ANXA6/GSTO1/RHOA/GJA1 16 GO:0001755 neural crest cell migration 6/320 55/18722 0.000340945812322408 0.00506758308099348 FN1/NRP2/EFNB1/ISL1/SEMA6D/ANXA6 6 GO:0014706 striated muscle tissue development 17/320 384/18722 0.000351895747407116 0.00521158863185019 IGF2/CAV1/GPX1/DSP/FLNB/VAMP5/ISL1/CDC42/ITGB1/TGFBR1/PLEC/CDK1/LRP2/RHOA/YBX3/CTNNB1/GJA1 17 GO:0032612 interleukin-1 production 9/320 128/18722 0.000357805271769231 0.00526139282188777 MNDA/TYROBP/CCL3/SERPINB1/ANXA1/ISL1/HMGB1/CARD16/HSPB1 9 GO:0032652 regulation of interleukin-1 production 9/320 128/18722 0.000357805271769231 0.00526139282188777 MNDA/TYROBP/CCL3/SERPINB1/ANXA1/ISL1/HMGB1/CARD16/HSPB1 9 GO:0032677 regulation of interleukin-8 production 8/320 102/18722 0.000363666143364116 0.00532861171766144 PTPRC/TMSB4X/FCN1/ANXA4/ANXA1/HMGB1/CD74/HSPA1A 8 GO:0031529 ruffle organization 6/320 56/18722 0.000376443283130501 0.00549449328896395 AIF1/PLEK/EPS8L1/CAV1/PFN1/SNX10 6 GO:0051250 negative regulation of lymphocyte activation 10/320 157/18722 0.000377937543132791 0.00549449328896395 MNDA/FGL2/LST1/TYROBP/LAPTM5/HLA-DRB1/ANXA1/HMGB1/CD74/CEBPB 10 GO:0034101 erythrocyte homeostasis 9/320 129/18722 0.000378976424819634 0.00549449328896395 ISG15/RPS17/KLF2/ZFP36/B2M/STAT1/HMOX1/UBA5/HSPA1A 9 GO:0032637 interleukin-8 production 8/320 103/18722 0.000388538153808549 0.00560049539552367 PTPRC/TMSB4X/FCN1/ANXA4/ANXA1/HMGB1/CD74/HSPA1A 8 GO:0045088 regulation of innate immune response 12/320 218/18722 0.000388998591121804 0.00560049539552367 MNDA/SERPINB9/HLA-A/HLA-B/FCN1/NCF1/TYROBP/ISG15/HLA-E/SAMHD1/PARP14/HMGB1 12 GO:0150105 protein localization to cell-cell junction 4/320 21/18722 0.000398347264808802 0.00571517672982628 FLNA/ACTG1/DSP/ACTB 4 GO:0032272 negative regulation of protein polymerization 7/320 79/18722 0.000403629112828475 0.00575702994484165 TMSB4X/MYADM/CAPG/PFN1/STMN1/CAPZA1/CAPZB 7 GO:0003015 heart process 13/320 251/18722 0.000404050988384337 0.00575702994484165 CYP2J2/FLNA/CXCR4/CAV1/GPX1/DSP/ISL1/ATP2B1/CDC42/SRI/PDE4B/GSTO1/GJA1 13 GO:0046634 regulation of alpha-beta T cell activation 8/320 104/18722 0.000414776575809286 0.0058895423066803 PTPRC/HLA-A/HLA-DRB1/HLA-DRA/HLA-E/ANXA1/HMGB1/RHOA 8 GO:0090257 regulation of muscle system process 13/320 252/18722 0.00041961871746589 0.0059378922622228 TNFRSF1B/AIF1/CAV1/C12orf57/DSP/ENO1/ATP2B1/SRI/PDE4B/PARP1/ANXA6/GSTO1/RHOA 13 GO:0043525 positive regulation of neuron apoptotic process 6/320 58/18722 0.000456065272801777 0.00641947978545858 TYROBP/CCL3/CDC42/JUN/RHOA/CTNNB1 6 GO:1904062 regulation of cation transmembrane transport 16/320 357/18722 0.000456758726264478 0.00641947978545858 TMSB4X/CTSS/FXYD5/FLNA/CORO1A/CAV1/C4orf3/CYBA/FXYD3/CD63/SRI/ITGB1/IFNGR2/SLC43A2/PDE4B/GSTO1 16 GO:0036294 cellular response to decreased oxygen levels 10/320 161/18722 0.000461265827273018 0.00646084880776987 CYBB/BNIP3L/ENO1/BACH1/PMAIP1/STC2/NAMPT/HMOX1/PGK1/CARD16 10 GO:0006096 glycolytic process 7/320 81/18722 0.000470324529469979 0.00654337022144766 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGK1 7 GO:0014032 neural crest cell development 7/320 81/18722 0.000470324529469979 0.00654337022144766 FN1/NRP2/EFNB1/ISL1/SEMA6D/ANXA6/PDCD6 7 GO:0002274 myeloid leukocyte activation 12/320 223/18722 0.000476866214002493 0.00661211810824934 PTPRC/AIF1/ITGB2/TYROBP/FCER1G/CCL3/HMGB1/IFNGR2/CD74/NAMPT/HMOX1/STXBP2 12 GO:0099563 modification of synaptic structure 4/320 22/18722 0.000480353791077657 0.00663820021649793 CDC42/PFN1/MYH10/RHOA 4 GO:0060759 regulation of response to cytokine stimulus 10/320 162/18722 0.000484324864221413 0.00666289406711159 PTPRC/LAPTM5/CXCR4/CAV1/ISG15/SAMHD1/PARP14/CD74/HSPA1A/CARD16 10 GO:1901653 cellular response to peptide 16/320 359/18722 0.000485365710116309 0.00666289406711159 VIM/IGF2/PKM/CAV1/CYBA/RPL23/CYP11A1/KLF2/FBN1/ATP2B1/NAMPT/PARP1/STAT1/PTPRA/ID1/GJA1 16 GO:2001234 negative regulation of apoptotic signaling pathway 12/320 224/18722 0.000496310320694937 0.00679057697056781 PLAUR/GPX1/ENO1/SOD2/TGFBR1/PTTG1IP/CD74/HMOX1/HSPA1A/YBX3/HSPB1/CTNNB1 12 GO:0001836 release of cytochrome c from mitochondria 6/320 59/18722 0.000500501187094884 0.00680286481932915 TNFSF10/PLAUR/GPX1/SOD2/PMAIP1/JUN 6 GO:0090303 positive regulation of wound healing 6/320 59/18722 0.000500501187094884 0.00680286481932915 CXCR4/ACTG1/ANXA1/HMGB1/ITGB1/PLPP3 6 GO:0002347 response to tumor cell 5/320 39/18722 0.000505320189110701 0.00684366586272722 TXNIP/HLA-A/LAPTM5/HLA-DRB1/HMGB1 5 GO:0006757 ATP generation from ADP 7/320 82/18722 0.00050681552613614 0.00684366586272722 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGK1 7 GO:0002285 lymphocyte activation involved in immune response 11/320 194/18722 0.000526992142809713 0.00709293659312617 PTPRC/FGL2/CORO1A/FCER1G/HLA-DRB1/LCP1/HLA-DRA/ANXA1/HMGB1/CD74/TFRC 11 GO:0002700 regulation of production of molecular mediator of immune response 10/320 164/18722 0.000533318760932835 0.00715478285770933 PTPRC/HLA-A/TNFRSF1B/BST2/LAPTM5/HLA-E/CD74/B2M/HMOX1/TFRC 10 GO:0071803 positive regulation of podosome assembly 3/320 10/18722 0.000542998862154262 0.00720164385206364 LCP1/MSN/RHOA 3 GO:0098885 modification of postsynaptic actin cytoskeleton 3/320 10/18722 0.000542998862154262 0.00720164385206364 PFN1/MYH10/RHOA 3 GO:0048732 gland development 18/320 436/18722 0.000545273761908746 0.00720164385206364 IGF2/TSPO/CAV1/MSN/LBH/LMO4/GPX1/ANXA1/WLS/KRT18/ISL1/CDC42/TGFBR1/PSAP/HMOX1/EZH2/CTNNB1/CEBPB 18 GO:0031397 negative regulation of protein ubiquitination 7/320 83/18722 0.000545526264689235 0.00720164385206364 TSPO/CAV1/ISG15/RPL23/RPL37/HSPA1A/SOX4 7 GO:0048678 response to axon injury 7/320 83/18722 0.000545526264689235 0.00720164385206364 AIF1/TSPO/FLNA/TYROBP/ISL1/NREP/CDK1 7 GO:0031667 response to nutrient levels 19/320 474/18722 0.000551503121813828 0.00725735955202145 LDHA/CYBB/UPP1/TSPO/PAGE4/CD68/CYBA/MBD3/ZFP36/SOD2/PMAIP1/KRT18/STC2/ATP2B1/JUN/PLEC/NAMPT/STAT1/HMOX1 19 GO:0050714 positive regulation of protein secretion 9/320 137/18722 0.000588407372853762 0.00771841036391029 HLA-DRB1/EZR/WLS/DYNLL1/ISL1/SRI/MYH10/SOX4/GJA1 9 GO:0032611 interleukin-1 beta production 8/320 110/18722 0.000604114057917022 0.00787444570130327 MNDA/TYROBP/CCL3/SERPINB1/ISL1/HMGB1/CARD16/HSPB1 8 GO:0032651 regulation of interleukin-1 beta production 8/320 110/18722 0.000604114057917022 0.00787444570130327 MNDA/TYROBP/CCL3/SERPINB1/ISL1/HMGB1/CARD16/HSPB1 8 GO:0060537 muscle tissue development 17/320 403/18722 0.000608228008357905 0.00790313877526687 IGF2/CAV1/GPX1/DSP/FLNB/VAMP5/ISL1/CDC42/ITGB1/TGFBR1/PLEC/CDK1/LRP2/RHOA/YBX3/CTNNB1/GJA1 17 GO:0140694 non-membrane-bounded organelle assembly 16/320 367/18722 0.000615724804321846 0.00797546987917827 KRT19/RPS27/FLNA/KRT8/LCP1/MSN/NEK6/EZR/ACTG1/CCSAP/RPS28/ITGB1/PLEC/TUBB/HSPA1A/RHOA 16 GO:0007179 transforming growth factor beta receptor signaling pathway 11/320 198/18722 0.000624882392703019 0.00806879389577773 PEG10/ZEB2/CAV1/HTRA1/FBN1/NREP/TGFBR1/JUN/PARP1/HSPA1A/ID1 11 GO:0001938 positive regulation of endothelial cell proliferation 8/320 111/18722 0.000641552333023354 0.00825823750795171 IGF2/NRP2/CYBA/PGF/HMGB1/TGFBR1/HMOX1/PDCD6 8 GO:0032731 positive regulation of interleukin-1 beta production 6/320 62/18722 0.000654260956863734 0.0083956716576427 MNDA/TYROBP/CCL3/ISL1/HMGB1/HSPB1 6 GO:0006937 regulation of muscle contraction 10/320 169/18722 0.000674021815963544 0.00862041937180452 CAV1/C12orf57/DSP/ENO1/ATP2B1/SRI/PDE4B/ANXA6/GSTO1/RHOA 10 GO:0014031 mesenchymal cell development 7/320 86/18722 0.000675947695175378 0.00862041937180452 FN1/NRP2/EFNB1/ISL1/SEMA6D/ANXA6/PDCD6 7 GO:0042063 gliogenesis 14/320 301/18722 0.000714797122315886 0.00904786908544621 VIM/TNFRSF1B/TSPO/CXCR4/CCL3/ANXA1/PLEC/CDK1/S100A9/LRP2/RHOA/EZH2/CTNNB1/SOX4 14 GO:0030890 positive regulation of B cell proliferation 5/320 42/18722 0.000716034170121227 0.00904786908544621 PTPRC/TNFSF13B/CD74/SLC39A10/TFRC 5 GO:0045214 sarcomere organization 5/320 42/18722 0.000716034170121227 0.00904786908544621 KRT19/KRT8/ACTG1/ITGB1/PLEC 5 GO:0002708 positive regulation of lymphocyte mediated immunity 8/320 113/18722 0.000722045543931918 0.00909601276684965 PTPRC/HLA-A/HLA-B/HLA-DRB1/HLA-DRA/HLA-E/B2M/TFRC 8 GO:0002604 regulation of dendritic cell antigen processing and presentation 3/320 11/18722 0.000737195197228253 0.00923057743923377 FGL2/CD68/CD74 3 GO:0045657 positive regulation of monocyte differentiation 3/320 11/18722 0.000737195197228253 0.00923057743923377 HLA-DRB1/JUN/CD74 3 GO:0007162 negative regulation of cell adhesion 14/320 303/18722 0.000762338212741647 0.00951656040800147 PTPRC/FGL2/FXYD5/MYADM/LAPTM5/HLA-DRB1/ARHGDIB/FBLN1/ANXA1/HMGB1/CD74/GBP1/RHOA/CEBPB 14 GO:0002286 T cell activation involved in immune response 8/320 114/18722 0.000765235078403094 0.0095239498312096 FGL2/FCER1G/HLA-DRB1/LCP1/HLA-DRA/ANXA1/HMGB1/CD74 8 GO:0030837 negative regulation of actin filament polymerization 6/320 64/18722 0.000775515031973611 0.00962290724358847 TMSB4X/MYADM/CAPG/PFN1/CAPZA1/CAPZB 6 GO:0007568 aging 15/320 339/18722 0.000778390680870248 0.00962967153699361 TNFRSF1B/TSPO/CD68/NEK6/TIMP2/MBD3/SOD2/LITAF/ATP2B1/JUN/NAMPT/B2M/CDK1/GPX4/PDCD4 15 GO:0031579 membrane raft organization 4/320 25/18722 0.000797820061551184 0.00982637670120475 PTPRC/MYADM/CAV1/PPT1 4 GO:0036230 granulocyte activation 5/320 43/18722 0.000799047088965342 0.00982637670120475 ITGB2/TYROBP/FCER1G/CCL3/STXBP2 5 GO:0001890 placenta development 9/320 144/18722 0.000841833076747337 0.0102878985485751 KRT19/IGF2/KRT8/HTRA1/STC2/PHLDA2/CTSB/GJA1/CEBPB 9 GO:0010821 regulation of mitochondrion organization 9/320 144/18722 0.000841833076747337 0.0102878985485751 TNFSF10/TSPO/PLAUR/GPX1/BNIP3L/PMAIP1/HSPA1A/VPS13C/TFRC 9 GO:0045619 regulation of lymphocyte differentiation 10/320 174/18722 0.000844045887697719 0.0102878985485751 PTPRC/FGL2/HLA-DRB1/HLA-DRA/ANXA1/HMGB1/ZFP36L2/CD74/RHOA/SOX4 10 GO:0046031 ADP metabolic process 7/320 90/18722 0.000886993295604191 0.0107726529678901 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGK1 7 GO:0097178 ruffle assembly 5/320 44/18722 0.000889030653932846 0.0107726529678901 AIF1/EPS8L1/CAV1/PFN1/SNX10 5 GO:0006909 phagocytosis 14/320 308/18722 0.00089302944440651 0.0107894668546424 PTPRC/AIF1/NCF2/ITGB2/FCN1/TYROBP/CORO1A/FCER1G/CYBA/ANXA1/CDC42/HMGB1/ITGB1/MYH9 14 GO:0016064 immunoglobulin mediated immune response 11/320 207/18722 0.000901458292745328 0.0108595500455501 PTPRC/HLA-DMA/HLA-DPA1/FCER1G/HLA-DRB1/HLA-DRA/HLA-DPB1/HLA-E/CD74/B2M/TFRC 11 GO:0072678 T cell migration 6/320 66/18722 0.000913426701352794 0.0109717416569469 AIF1/MSN/CCL3/CD99/PLEC/RHOA 6 GO:0043534 blood vessel endothelial cell migration 10/320 176/18722 0.000921249919376937 0.0110336367155522 TMSB4X/GPX1/ANXA1/HMGB1/ITGB1/MYH9/HMOX1/RHOA/ID1/HSPB1 10 GO:0045580 regulation of T cell differentiation 9/320 146/18722 0.000928617291189554 0.0110897301942059 PTPRC/FGL2/HLA-DRB1/HLA-DRA/ANXA1/HMGB1/CD74/RHOA/SOX4 9 GO:0043270 positive regulation of ion transport 13/320 275/18722 0.000946910465317793 0.0111812059314558 TMSB4X/CTSS/TSPO/FLNA/CAV1/CCL3/ATP2B1/SRI/ITGB1/IFNGR2/TCAF1/GSTO1/CEBPB 13 GO:0002275 myeloid cell activation involved in immune response 7/320 91/18722 0.000947101180060393 0.0111812059314558 ITGB2/TYROBP/FCER1G/CCL3/HMGB1/HMOX1/STXBP2 7 GO:0014033 neural crest cell differentiation 7/320 91/18722 0.000947101180060393 0.0111812059314558 FN1/NRP2/EFNB1/ISL1/SEMA6D/ANXA6/PDCD6 7 GO:0045582 positive regulation of T cell differentiation 7/320 91/18722 0.000947101180060393 0.0111812059314558 PTPRC/HLA-DRB1/HLA-DRA/ANXA1/CD74/RHOA/SOX4 7 GO:0032409 regulation of transporter activity 14/320 310/18722 0.000950353019076242 0.0111876315522024 TMSB4X/CTSS/FXYD5/CAV1/C4orf3/FXYD3/SRI/ITGB1/IFNGR2/TCAF1/PDE4B/GSTO1/ACTB/GJA1 14 GO:0045446 endothelial cell differentiation 8/320 118/18722 0.000959246328147488 0.0112602438292768 MYADM/CXCR4/MSN/EZR/GPX1/CLIC4/ID1/CTNNB1 8 GO:0002424 T cell mediated immune response to tumor cell 3/320 12/18722 0.000970525093847951 0.0112646339544375 HLA-A/HLA-DRB1/HMGB1 3 GO:0043380 regulation of memory T cell differentiation 3/320 12/18722 0.000970525093847951 0.0112646339544375 FGL2/HLA-DRB1/HLA-DRA 3 GO:0048548 regulation of pinocytosis 3/320 12/18722 0.000970525093847951 0.0112646339544375 CAV1/CDC42/PPT1 3 GO:0070493 thrombin-activated receptor signaling pathway 3/320 12/18722 0.000970525093847951 0.0112646339544375 PLEK/STMN1/IQGAP2 3 GO:1902850 microtubule cytoskeleton organization involved in mitosis 9/320 147/18722 0.000974656022661374 0.0112808926768538 FLNA/NEK6/CCSAP/ITGB1/STMN1/SPC25/HSPA1A/RHOA/GJA1 9 GO:0010639 negative regulation of organelle organization 15/320 347/18722 0.000984981420220865 0.0113685565037783 TMSB4X/GMFG/TSPO/CORO1A/MYADM/GPX1/CAPG/PFN1/STMN1/PARP1/CAPZA1/CAPZB/HSPA1A/TOP2A/TFRC 15 GO:0019724 B cell mediated immunity 11/320 210/18722 0.00101357657225258 0.0116660122466509 PTPRC/HLA-DMA/HLA-DPA1/FCER1G/HLA-DRB1/HLA-DRA/HLA-DPB1/HLA-E/CD74/B2M/TFRC 11 GO:0097530 granulocyte migration 9/320 148/18722 0.00102252927791293 0.011703853120045 ITGB2/CCL3L3/FCER1G/CCL3/ANXA1/CD99/CD74/PDE4B/S100A9 9 GO:1903900 regulation of viral life cycle 9/320 148/18722 0.00102252927791293 0.011703853120045 IFITM2/MX1/FCN1/APOBEC3A/BST2/HLA-DRB1/ISG15/CD74/TOP2A 9 GO:0006941 striated muscle contraction 10/320 179/18722 0.00104784586946502 0.0119559548517626 ALDOA/FLNA/CXCR4/CAV1/C12orf57/DSP/SRI/PDE4B/GSTO1/GJA1 10 GO:0050727 regulation of inflammatory response 16/320 386/18722 0.00105034162903917 0.0119559548517626 PTPRC/TMSB4X/TNFRSF1B/NCF1/HLA-DRB1/CCL3/GPX1/ZFP36/HLA-E/ANXA1/ISL1/GPX4/S100A9/PBK/PDCD4/CEBPB 16 GO:0042267 natural killer cell mediated cytotoxicity 6/320 68/18722 0.00106948158108099 0.0121403788269963 SERPINB9/HLA-A/HLA-B/CORO1A/HLA-E/TUBB 6 GO:0009749 response to glucose 11/320 212/18722 0.00109453716515567 0.012390760455954 TXNIP/LDHA/HLA-DRB1/CYBA/DYNLL1/SRI/HMGN3/TRA2B/RHOA/SOX4/GJA1 11 GO:0030316 osteoclast differentiation 7/320 94/18722 0.00114685854312816 0.012931753063354 TYROBP/CCL3/FBN1/SNX10/CTNNB1/TFRC/CEBPB 7 GO:0032103 positive regulation of response to external stimulus 17/320 427/18722 0.00114858503733082 0.012931753063354 MNDA/TMSB4X/AIF1/FCN1/FLNA/TYROBP/CXCR4/CCL3/CYBA/HLA-E/PGF/HMGB1/CD74/S100A9/HSPB1/PDCD4/CEBPB 17 GO:0071456 cellular response to hypoxia 9/320 151/18722 0.00117769770102417 0.0131876609773222 CYBB/BNIP3L/ENO1/BACH1/PMAIP1/STC2/HMOX1/PGK1/CARD16 9 GO:2001236 regulation of extrinsic apoptotic signaling pathway 9/320 151/18722 0.00117769770102417 0.0131876609773222 PTPRC/TNFSF10/CAV1/GPX1/PMAIP1/TIMP3/TGFBR1/HMOX1/HSPA1A 9 GO:1990266 neutrophil migration 8/320 122/18722 0.00119079982300481 0.0132983374828537 ITGB2/CCL3L3/FCER1G/CCL3/CD99/CD74/PDE4B/S100A9 8 GO:0045646 regulation of erythrocyte differentiation 5/320 47/18722 0.00120441434179749 0.0134141241517715 ISG15/ZFP36/B2M/STAT1/HSPA1A 5 GO:0002764 immune response-regulating signaling pathway 18/320 468/18722 0.00122459589942182 0.0136022318720725 PTPRC/MNDA/HLA-A/CTSS/FCN1/TYROBP/LAPTM5/FCER1G/CAV1/HLA-DRB1/CYBA/EZR/HLA-DPB1/HMGB1/PDE4B/GBP1/SLC39A10/HSPA1A 18 GO:0002548 monocyte chemotaxis 6/320 70/18722 0.00124521788186555 0.0136902946300458 AIF1/CCL3L3/CCL3/ANXA1/HMGB1/FLT1 6 GO:0043379 memory T cell differentiation 3/320 13/18722 0.00124577705249206 0.0136902946300458 FGL2/HLA-DRB1/HLA-DRA 3 GO:0071801 regulation of podosome assembly 3/320 13/18722 0.00124577705249206 0.0136902946300458 LCP1/MSN/RHOA 3 GO:2001198 regulation of dendritic cell differentiation 3/320 13/18722 0.00124577705249206 0.0136902946300458 HLA-B/HMGB1/CEBPB 3 GO:0030168 platelet activation 8/320 123/18722 0.00125513157572886 0.0137201155315123 PLEK/FLNA/FN1/FCER1G/ACTG1/MYH9/ACTB/HSPB1 8 GO:0050852 T cell receptor signaling pathway 8/320 123/18722 0.00125513157572886 0.0137201155315123 PTPRC/HLA-A/LAPTM5/HLA-DRB1/EZR/HLA-DPB1/PDE4B/GBP1 8 GO:0007051 spindle organization 10/320 184/18722 0.00129027530750765 0.0140599471176527 FLNA/NEK6/EZR/CCSAP/STMN1/MYH9/SPC25/TUBB/HSPA1A/RHOA 10 GO:0071560 cellular response to transforming growth factor beta stimulus 12/320 250/18722 0.00129302514634754 0.0140599471176527 PEG10/ZEB2/CAV1/HTRA1/FBN1/NREP/ZFP36L2/TGFBR1/JUN/PARP1/HSPA1A/ID1 12 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 5/320 48/18722 0.00132591346393143 0.0143797229211672 PTPRC/TNFSF10/CAV1/PMAIP1/TIMP3 5 GO:0002228 natural killer cell mediated immunity 6/320 71/18722 0.00134096079084717 0.0145048428999489 SERPINB9/HLA-A/HLA-B/CORO1A/HLA-E/TUBB 6 GO:0016052 carbohydrate catabolic process 9/320 154/18722 0.00135136369863038 0.0145792031403153 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PYGL/HMGB1/PGK1 9 GO:0010951 negative regulation of endopeptidase activity 12/320 252/18722 0.00138356188783487 0.0148877023972231 GAPDH/SERPINB9/SERPINA1/BST2/PLAUR/GPX1/TIMP2/SERPINB1/TIMP3/TFPI2/DHCR24/CARD16 12 GO:0071621 granulocyte chemotaxis 8/320 125/18722 0.00139209090307392 0.0149405704194843 ITGB2/CCL3L3/FCER1G/CCL3/ANXA1/CD74/PDE4B/S100A9 8 GO:0007519 skeletal muscle tissue development 9/320 155/18722 0.00141363219670463 0.0151324565719781 IGF2/CAV1/GPX1/FLNB/VAMP5/PLEC/RHOA/YBX3/CTNNB1 9 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 4/320 29/18722 0.0014196019296673 0.0151570934712798 GPX1/SOD2/PARP1/HSPB1 4 GO:0097305 response to alcohol 12/320 253/18722 0.00143075867219594 0.0152368423544165 CYBB/TSPO/CCL3/CYBA/KLF2/SOD2/ATP2B1/TGFBR1/PARP1/CDK1/RHOA/CTNNB1 12 GO:0032729 positive regulation of interferon-gamma production 6/320 72/18722 0.00144222295264668 0.0153107122824384 HLA-A/HLA-DPA1/ISG15/HLA-DPB1/ISL1/PDE4B 6 GO:0030857 negative regulation of epithelial cell differentiation 5/320 49/18722 0.00145622215077403 0.0153107122824384 CAV1/STAT1/ID1/EZH2/CTNNB1 5 GO:0034332 adherens junction organization 5/320 49/18722 0.00145622215077403 0.0153107122824384 DSP/CDC42/PLEC/ACTB/CTNNB1 5 GO:0038084 vascular endothelial growth factor signaling pathway 5/320 49/18722 0.00145622215077403 0.0153107122824384 NRP2/CD63/PGF/FLT1/HSPB1 5 GO:0052372 modulation by symbiont of entry into host 5/320 49/18722 0.00145622215077403 0.0153107122824384 IFITM2/FCN1/CAV1/HLA-DRB1/CD74 5 GO:0061337 cardiac conduction 7/320 98/18722 0.00146297642464573 0.0153238054431623 FLNA/CAV1/DSP/ISL1/ATP2B1/SRI/GJA1 7 GO:2001235 positive regulation of apoptotic signaling pathway 8/320 126/18722 0.00146488459584925 0.0153238054431623 PTPRC/TNFSF10/CAV1/PMAIP1/TIMP3/TGFBR1/S100A9/MAGED1 8 GO:0002064 epithelial cell development 11/320 220/18722 0.00147360081532341 0.015376056992213 VIM/FLNA/MYADM/CXCR4/MSN/EZR/GPX1/FLNB/ADAMTSL4/CLIC4/PLEC 11 GO:0046631 alpha-beta T cell activation 9/320 156/18722 0.0014781896877513 0.0153850876317087 PTPRC/HLA-A/HLA-DRB1/HLA-DRA/HLA-E/ANXA1/HMGB1/CTSL/RHOA 9 GO:0010810 regulation of cell-substrate adhesion 11/320 221/18722 0.00152774708836728 0.0157535179432301 FLNA/MYADM/PLEKHA2/FN1/CCDC80/ACTG1/FBLN1/CDC42/GBP1/PTPRA/RHOA 11 GO:0030048 actin filament-based movement 8/320 127/18722 0.00154066711016819 0.0157535179432301 FLNA/CAV1/DSP/SRI/MYH9/PDE4B/MYH10/GJA1 8 GO:0001837 epithelial to mesenchymal transition 9/320 157/18722 0.00154509691276189 0.0157535179432301 FLNA/ISL1/TGFBR1/HNRNPAB/S100A4/EZH2/CTNNB1/PDCD6/PDCD4 9 GO:0032732 positive regulation of interleukin-1 production 6/320 73/18722 0.00154920986466334 0.0157535179432301 MNDA/TYROBP/CCL3/ISL1/HMGB1/HSPB1 6 GO:0035924 cellular response to vascular endothelial growth factor stimulus 6/320 73/18722 0.00154920986466334 0.0157535179432301 NRP2/ANXA1/CD63/PGF/FLT1/HSPB1 6 GO:0086003 cardiac muscle cell contraction 6/320 73/18722 0.00154920986466334 0.0157535179432301 FLNA/CAV1/DSP/SRI/PDE4B/GJA1 6 GO:0002444 myeloid leukocyte mediated immunity 7/320 99/18722 0.00155171389227848 0.0157535179432301 SERPINB9/ITGB2/TYROBP/CCL3/HLA-E/HMOX1/STXBP2 7 GO:0006165 nucleoside diphosphate phosphorylation 7/320 99/18722 0.00155171389227848 0.0157535179432301 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGK1 7 GO:0030838 positive regulation of actin filament polymerization 7/320 99/18722 0.00155171389227848 0.0157535179432301 GMFG/CORO1A/PFN1/IQGAP2/VASP/ACTR3/RHOA 7 GO:0042100 B cell proliferation 7/320 99/18722 0.00155171389227848 0.0157535179432301 PTPRC/MNDA/TNFSF13B/TYROBP/CD74/SLC39A10/TFRC 7 GO:0090715 immunological memory formation process 3/320 14/18722 0.00156556306847841 0.0158430440157065 FGL2/HLA-DRB1/HLA-DRA 3 GO:0007517 muscle organ development 14/320 327/18722 0.00157508446618154 0.0158430440157065 IGF2/CAV1/GPX1/DSP/FLNB/VAMP5/ISL1/SRI/TGFBR1/PLEC/LRP2/RHOA/YBX3/CTNNB1 14 GO:0002429 immune response-activating cell surface receptor signaling pathway 13/320 291/18722 0.00157586909255938 0.0158430440157065 PTPRC/MNDA/HLA-A/FCN1/TYROBP/LAPTM5/FCER1G/HLA-DRB1/EZR/HLA-DPB1/PDE4B/GBP1/SLC39A10 13 GO:0002757 immune response-activating signal transduction 13/320 291/18722 0.00157586909255938 0.0158430440157065 PTPRC/MNDA/HLA-A/FCN1/TYROBP/LAPTM5/FCER1G/HLA-DRB1/EZR/HLA-DPB1/PDE4B/GBP1/SLC39A10 13 GO:0071559 response to transforming growth factor beta 12/320 256/18722 0.00158039642912873 0.0158499952552425 PEG10/ZEB2/CAV1/HTRA1/FBN1/NREP/ZFP36L2/TGFBR1/JUN/PARP1/HSPA1A/ID1 12 GO:0001961 positive regulation of cytokine-mediated signaling pathway 5/320 50/18722 0.00159572022199959 0.0159649296786981 LAPTM5/CXCR4/PARP14/CD74/HSPA1A 5 GO:1903201 regulation of oxidative stress-induced cell death 6/320 74/18722 0.00166212962957999 0.0165891778488515 PAGE4/GPX1/SOD2/PARP1/HSPB1/CTNNB1 6 GO:0022411 cellular component disassembly 17/320 443/18722 0.00170092561274367 0.0169354810406189 CTSS/PLEK/TSPO/LCP1/NEK6/RPL23/CCSAP/BNIP3L/CAPG/STMN1/TGFBR1/CDK1/CAPZA1/CAPZB/UBA5/VPS13C/TOP2A 17 GO:0046939 nucleotide phosphorylation 7/320 101/18722 0.00174173102074178 0.0172475469044296 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGK1 7 GO:0098869 cellular oxidant detoxification 7/320 101/18722 0.00174173102074178 0.0172475469044296 GPX3/GPX1/SOD2/GSTO1/GPX4/S100A9/SOD3 7 GO:0045104 intermediate filament cytoskeleton organization 5/320 51/18722 0.00174479056293601 0.0172475469044296 VIM/DSP/KRT18/PLEC/DST 5 GO:0002292 T cell differentiation involved in immune response 6/320 75/18722 0.00178119283236246 0.0175235447221944 FGL2/FCER1G/HLA-DRB1/HLA-DRA/ANXA1/HMGB1 6 GO:0048662 negative regulation of smooth muscle cell proliferation 6/320 75/18722 0.00178119283236246 0.0175235447221944 AIF1/SOD2/IGFBP3/HMOX1/RHOA/PDCD4 6 GO:1902106 negative regulation of leukocyte differentiation 7/320 102/18722 0.00184327264328539 0.018091217487067 FGL2/CCL3/ANXA1/FBN1/HMGB1/CD74/CTNNB1 7 GO:0019079 viral genome replication 8/320 131/18722 0.00187542558981461 0.0183631718888957 IFITM2/MX1/APOBEC3A/BST2/ISG15/CDC42/DEK/TOP2A 8 GO:0043392 negative regulation of DNA binding 5/320 52/18722 0.0019038187225346 0.0185367588223338 TMSB4X/SRI/JUN/HMOX1/ID1 5 GO:0045103 intermediate filament-based process 5/320 52/18722 0.0019038187225346 0.0185367588223338 VIM/DSP/KRT18/PLEC/DST 5 GO:0031100 animal organ regeneration 6/320 76/18722 0.00190661241517228 0.0185367588223338 LCP1/PGF/HMOX1/CDK1/EZH2/CEBPB 6 GO:0051494 negative regulation of cytoskeleton organization 9/320 162/18722 0.00191706434550527 0.0185648364001392 TMSB4X/GMFG/CORO1A/MYADM/CAPG/PFN1/STMN1/CAPZA1/CAPZB 9 GO:0010466 negative regulation of peptidase activity 12/320 262/18722 0.00191848623980141 0.0185648364001392 GAPDH/SERPINB9/SERPINA1/BST2/PLAUR/GPX1/TIMP2/SERPINB1/TIMP3/TFPI2/DHCR24/CARD16 12 GO:0003279 cardiac septum development 7/320 103/18722 0.00194934703314308 0.0186739181412197 NRP2/LMO4/ISL1/TGFBR1/ADAMTS6/LRP2/SOX4 7 GO:0009135 purine nucleoside diphosphate metabolic process 7/320 103/18722 0.00194934703314308 0.0186739181412197 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGK1 7 GO:0009179 purine ribonucleoside diphosphate metabolic process 7/320 103/18722 0.00194934703314308 0.0186739181412197 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGK1 7 GO:0030593 neutrophil chemotaxis 7/320 103/18722 0.00194934703314308 0.0186739181412197 ITGB2/CCL3L3/FCER1G/CCL3/CD74/PDE4B/S100A9 7 GO:0045862 positive regulation of proteolysis 15/320 372/18722 0.00195235543005975 0.0186739181412197 TNFRSF1B/TNFSF10/LAPTM5/FN1/CAV1/FBLN1/ENO1/PMAIP1/HMGB1/DDA1/MYH9/S100A9/HSPA1A/RHOA/PDCD6 15 GO:0003018 vascular process in circulatory system 12/320 263/18722 0.00198021477679618 0.0188531047412945 SLC2A3/CAV1/GPX1/KLF2/SOD2/ATP2B1/PLEC/SOD3/LRP2/RHOA/GJA1/TFRC 12 GO:0043588 skin development 12/320 263/18722 0.00198021477679618 0.0188531047412945 TXNIP/ZFP36/ANXA1/DSP/FLNB/ARRDC3/STMN1/CLIC4/PLEC/DHCR24/CTNNB1/LGR5 12 GO:0010038 response to metal ion 15/320 373/18722 0.00200347980823826 0.0190307553279091 TXNIP/CYBB/NCF1/TSPO/CAV1/FUS/SOD2/JUN/CLIC4/B2M/PARP1/HMOX1/CDK1/SOD3/PDCD6 15 GO:0031016 pancreas development 6/320 77/18722 0.00203860355037576 0.0193199767664051 IGF2/ANXA1/WLS/ISL1/CTNNB1/SOX4 6 GO:0045621 positive regulation of lymphocyte differentiation 7/320 104/18722 0.002060089231095 0.0194178845218901 PTPRC/HLA-DRB1/HLA-DRA/ANXA1/CD74/RHOA/SOX4 7 GO:0048661 positive regulation of smooth muscle cell proliferation 7/320 104/18722 0.002060089231095 0.0194178845218901 AIF1/CYBA/JUN/NAMPT/STAT1/HMOX1/GJA1 7 GO:0010595 positive regulation of endothelial cell migration 8/320 133/18722 0.00206303274567032 0.0194178845218901 TMSB4X/NRP2/ANXA1/HMGB1/HMOX1/PLPP3/HSPB1/PDCD6 8 GO:0002707 negative regulation of lymphocyte mediated immunity 5/320 53/18722 0.00207319251427991 0.0194250146689446 PTPRC/SERPINB9/HLA-A/HLA-B/HLA-E 5 GO:1903202 negative regulation of oxidative stress-induced cell death 5/320 53/18722 0.00207319251427991 0.0194250146689446 PAGE4/GPX1/SOD2/HSPB1/CTNNB1 5 GO:0010952 positive regulation of peptidase activity 10/320 197/18722 0.00214019540459568 0.0200074375832338 TNFSF10/LAPTM5/FN1/CAV1/FBLN1/PMAIP1/HMGB1/S100A9/RHOA/PDCD6 10 GO:0043434 response to peptide hormone 16/320 414/18722 0.00214740967449499 0.0200295638262151 CYBB/TNFSF10/IGF2/PKM/CAV1/CYBA/CYP11A1/ANXA1/FBN1/STC2/ATP2B1/PARP1/STAT1/PTPRA/VPS13C/GJA1 16 GO:0061041 regulation of wound healing 8/320 134/18722 0.00216221395370304 0.0200823735374626 CXCR4/CAV1/ACTG1/ANXA1/HMGB1/ITGB1/PLPP3/GJA1 8 GO:0045732 positive regulation of protein catabolic process 11/320 231/18722 0.00216436265271662 0.0200823735374626 TNFRSF1B/LAPTM5/CAV1/MSN/EZR/OAZ1/DDA1/PTTG1IP/HSPA1A/LRP2/GJA1 11 GO:0032635 interleukin-6 production 9/320 165/18722 0.00217251233573228 0.0200823735374626 HLA-B/AIF1/TYROBP/CYBA/KLF2/ISL1/HMGB1/CD74/CEBPB 9 GO:0032675 regulation of interleukin-6 production 9/320 165/18722 0.00217251233573228 0.0200823735374626 HLA-B/AIF1/TYROBP/CYBA/KLF2/ISL1/HMGB1/CD74/CEBPB 9 GO:0032024 positive regulation of insulin secretion 6/320 78/18722 0.00217738351183024 0.0200824747117915 HLA-DRB1/DYNLL1/ISL1/SRI/SOX4/GJA1 6 GO:0032412 regulation of ion transmembrane transporter activity 12/320 267/18722 0.00224364315676291 0.0206475134159117 TMSB4X/CTSS/FXYD5/CAV1/C4orf3/FXYD3/SRI/ITGB1/IFNGR2/TCAF1/PDE4B/GSTO1 12 GO:0060538 skeletal muscle organ development 9/320 166/18722 0.00226343883468516 0.0207373154432796 IGF2/CAV1/GPX1/FLNB/VAMP5/PLEC/RHOA/YBX3/CTNNB1 9 GO:1902904 negative regulation of supramolecular fiber organization 9/320 166/18722 0.00226343883468516 0.0207373154432796 TMSB4X/GMFG/CORO1A/MYADM/CAPG/PFN1/STMN1/CAPZA1/CAPZB 9 GO:0006090 pyruvate metabolic process 7/320 106/18722 0.00229612484889701 0.0208977706511948 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGK1 7 GO:0009185 ribonucleoside diphosphate metabolic process 7/320 106/18722 0.00229612484889701 0.0208977706511948 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGK1 7 GO:1903707 negative regulation of hemopoiesis 7/320 106/18722 0.00229612484889701 0.0208977706511948 FGL2/CCL3/ANXA1/FBN1/HMGB1/CD74/CTNNB1 7 GO:0032633 interleukin-4 production 4/320 33/18722 0.00231816732731592 0.0210058495536609 FCER1G/HLA-DRB1/HLA-E/CEBPB 4 GO:0032673 regulation of interleukin-4 production 4/320 33/18722 0.00231816732731592 0.0210058495536609 FCER1G/HLA-DRB1/HLA-E/CEBPB 4 GO:0010649 regulation of cell communication by electrical coupling 3/320 16/18722 0.00234834070132178 0.0211401825225742 CAV1/SRI/GJA1 3 GO:0051014 actin filament severing 3/320 16/18722 0.00234834070132178 0.0211401825225742 GMFG/CAPG/MYH9 3 GO:0051238 sequestering of metal ion 3/320 16/18722 0.00234834070132178 0.0211401825225742 FTH1/SRI/S100A9 3 GO:1903034 regulation of response to wounding 9/320 167/18722 0.00235736811054927 0.021175315288673 FLNA/CXCR4/CAV1/ACTG1/ANXA1/HMGB1/ITGB1/PLPP3/GJA1 9 GO:0048145 regulation of fibroblast proliferation 6/320 80/18722 0.0024761887334505 0.0221943857844196 FN1/FTH1/S100A6/IFI30/CD74/CTNNB1 6 GO:0060048 cardiac muscle contraction 8/320 137/18722 0.00248240010541656 0.0222018987783143 FLNA/CXCR4/CAV1/DSP/SRI/PDE4B/GSTO1/GJA1 8 GO:0034446 substrate adhesion-dependent cell spreading 7/320 108/18722 0.00255248964909949 0.022779454060646 FLNA/MYADM/FN1/FBLN1/CDC42/GBP1/RHOA 7 GO:0055094 response to lipoprotein particle 4/320 34/18722 0.00259234092839404 0.0229781390384453 ITGB2/FCER1G/CD68/ITGB1 4 GO:0086004 regulation of cardiac muscle cell contraction 4/320 34/18722 0.00259234092839404 0.0229781390384453 CAV1/DSP/SRI/PDE4B 4 GO:0006816 calcium ion transport 16/320 422/18722 0.0025968444178122 0.0229781390384453 PTPRC/TSPO/CORO1A/CXCR4/CAV1/C4orf3/CCL3/CYBA/ATP2B1/SRI/PDE4B/ANXA6/GSTO1/RHOA/CTNNB1/GJA1 16 GO:0032273 positive regulation of protein polymerization 8/320 138/18722 0.00259699683711373 0.0229781390384453 GMFG/CORO1A/PFN1/IQGAP2/VASP/HSPA1A/ACTR3/RHOA 8 GO:0001960 negative regulation of cytokine-mediated signaling pathway 6/320 81/18722 0.00263665786976894 0.0231260222148185 PTPRC/CAV1/ISG15/SAMHD1/PARP14/CARD16 6 GO:0048144 fibroblast proliferation 6/320 81/18722 0.00263665786976894 0.0231260222148185 FN1/FTH1/S100A6/IFI30/CD74/CTNNB1 6 GO:0002886 regulation of myeloid leukocyte mediated immunity 5/320 56/18722 0.00264729150716582 0.0231260222148185 ITGB2/TYROBP/HLA-E/HMOX1/STXBP2 5 GO:0043388 positive regulation of DNA binding 5/320 56/18722 0.00264729150716582 0.0231260222148185 PLAUR/ISL1/HMGB1/PARP1/CTNNB1 5 GO:0045071 negative regulation of viral genome replication 5/320 56/18722 0.00264729150716582 0.0231260222148185 IFITM2/MX1/APOBEC3A/BST2/ISG15 5 GO:0071385 cellular response to glucocorticoid stimulus 5/320 56/18722 0.00264729150716582 0.0231260222148185 ZFP36/ANXA1/ISL1/ATP2B1/ZFP36L2 5 GO:0001780 neutrophil homeostasis 3/320 17/18722 0.00281573010347794 0.0243401606434536 ANXA1/HMGB1/PDE4B 3 GO:0016045 detection of bacterium 3/320 17/18722 0.00281573010347794 0.0243401606434536 HLA-A/HLA-B/HLA-DRB1 3 GO:0045198 establishment of epithelial cell apical/basal polarity 3/320 17/18722 0.00281573010347794 0.0243401606434536 MSN/CDC42/RHOA 3 GO:0090713 immunological memory process 3/320 17/18722 0.00281573010347794 0.0243401606434536 FGL2/HLA-DRB1/HLA-DRA 3 GO:0097067 cellular response to thyroid hormone stimulus 3/320 17/18722 0.00281573010347794 0.0243401606434536 CTSS/CTSB/CTSL 3 GO:0051289 protein homotetramerization 5/320 57/18722 0.00286195749674411 0.0245854644003049 ALDOA/SAMHD1/SOD2/B2M/VASP 5 GO:0060760 positive regulation of response to cytokine stimulus 5/320 57/18722 0.00286195749674411 0.0245854644003049 LAPTM5/CXCR4/PARP14/CD74/HSPA1A 5 GO:1900024 regulation of substrate adhesion-dependent cell spreading 5/320 57/18722 0.00286195749674411 0.0245854644003049 FLNA/MYADM/FBLN1/CDC42/GBP1 5 GO:0033146 regulation of intracellular estrogen receptor signaling pathway 4/320 35/18722 0.00288796273774254 0.0246550868437028 LBH/ISL1/PARP1/UBA5 4 GO:0034405 response to fluid shear stress 4/320 35/18722 0.00288796273774254 0.0246550868437028 KLF2/PLEC/TFPI2/GJA1 4 GO:0035633 maintenance of blood-brain barrier 4/320 35/18722 0.00288796273774254 0.0246550868437028 ACTG1/ITGB1/ACTB/GJA1 4 GO:0008016 regulation of heart contraction 10/320 206/18722 0.00295738877764557 0.0250604104999606 CYP2J2/FLNA/CAV1/DSP/ISL1/ATP2B1/SRI/PDE4B/GSTO1/GJA1 10 GO:0032355 response to estradiol 8/320 141/18722 0.00296576494058101 0.0250604104999606 TXNIP/MBD3/ANXA1/CYP19A1/GPX4/EZH2/CTNNB1/GJA1 8 GO:0035296 regulation of tube diameter 8/320 141/18722 0.00296576494058101 0.0250604104999606 CAV1/GPX1/KLF2/SOD2/ATP2B1/SOD3/RHOA/GJA1 8 GO:0050921 positive regulation of chemotaxis 8/320 141/18722 0.00296576494058101 0.0250604104999606 TMSB4X/AIF1/CXCR4/CCL3/PGF/HMGB1/CD74/HSPB1 8 GO:0097746 blood vessel diameter maintenance 8/320 141/18722 0.00296576494058101 0.0250604104999606 CAV1/GPX1/KLF2/SOD2/ATP2B1/SOD3/RHOA/GJA1 8 GO:0051099 positive regulation of binding 9/320 173/18722 0.00298795518405774 0.0251963894296461 PLAUR/CAV1/ISL1/HMGB1/STMN1/B2M/PARP1/GMNN/CTNNB1 9 GO:0045861 negative regulation of proteolysis 14/320 351/18722 0.00301001194489558 0.0253306911533779 GAPDH/SERPINB9/SERPINA1/BST2/PLAUR/RPL23/GPX1/TIMP2/SERPINB1/TIMP3/TFPI2/DHCR24/PBK/CARD16 14 GO:0060249 anatomical structure homeostasis 13/320 314/18722 0.00305518540260585 0.0256585896007467 ALDOA/LYZ/CORO1A/ACTG1/ATP2B1/ITGB1/B2M/SNX10/ACTB/HSPB1/CTNNB1/GJA1/TFRC 13 GO:0002763 positive regulation of myeloid leukocyte differentiation 5/320 58/18722 0.00308892846126698 0.0257509817129193 EVI2B/TYROBP/HLA-DRB1/JUN/CD74 5 GO:0034340 response to type I interferon 5/320 58/18722 0.00308892846126698 0.0257509817129193 IFITM2/MX1/ISG15/SAMHD1/STAT1 5 GO:0086065 cell communication involved in cardiac conduction 5/320 58/18722 0.00308892846126698 0.0257509817129193 FLNA/CAV1/DSP/SRI/GJA1 5 GO:0007009 plasma membrane organization 8/320 142/18722 0.00309734702597311 0.0257509817129193 PTPRC/CXCR4/CAV1/MYH9/PLEC/ANXA6/S100A9/SPESP1 8 GO:0035150 regulation of tube size 8/320 142/18722 0.00309734702597311 0.0257509817129193 CAV1/GPX1/KLF2/SOD2/ATP2B1/SOD3/RHOA/GJA1 8 GO:0002768 immune response-regulating cell surface receptor signaling pathway 13/320 315/18722 0.00313903165807155 0.0260451381750033 PTPRC/MNDA/HLA-A/FCN1/TYROBP/LAPTM5/FCER1G/HLA-DRB1/EZR/HLA-DPB1/PDE4B/GBP1/SLC39A10 13 GO:1901215 negative regulation of neuron death 10/320 208/18722 0.00316902963375426 0.0262413435805062 TNFRSF1B/CORO1A/SOD2/ISL1/REL/HMOX1/PPT1/RHOA/CTNNB1/CEBPB 10 GO:0030224 monocyte differentiation 4/320 36/18722 0.00320583142500498 0.0263349810101801 HLA-DRB1/JUN/CD74/MYH9 4 GO:0042119 neutrophil activation 4/320 36/18722 0.00320583142500498 0.0263349810101801 ITGB2/TYROBP/FCER1G/STXBP2 4 GO:0051385 response to mineralocorticoid 4/320 36/18722 0.00320583142500498 0.0263349810101801 CYBB/CYBA/ATP2B1/PARP1 4 GO:0071402 cellular response to lipoprotein particle stimulus 4/320 36/18722 0.00320583142500498 0.0263349810101801 ITGB2/FCER1G/CD68/ITGB1 4 GO:0022900 electron transport chain 9/320 175/18722 0.00322541661268325 0.0264432965150936 NCF2/CYBB/NCF1/CYBA/CYP19A1/PLEC/NDUFB1/CDK1/NDUFB7 9 GO:0070555 response to interleukin-1 8/320 143/18722 0.00323342775718703 0.026456482163756 CCL3L3/CCL3/GBP2/CYBA/KLF2/ANXA1/GBP1/CEBPB 8 GO:0031623 receptor internalization 7/320 113/18722 0.00328982205183641 0.0268647128817945 ITGB2/FCER1G/CAV1/EZR/CD63/ITGB1/TFRC 7 GO:0006898 receptor-mediated endocytosis 11/320 244/18722 0.00329788473263422 0.0268774353357882 ITGB2/FCER1G/CAV1/EZR/CD63/ITGB1/B2M/CTSL/PPT1/LRP2/TFRC 11 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 14/320 355/18722 0.00333035462323449 0.0270849835947389 PEG10/VIM/ZEB2/CAV1/HTRA1/FBN1/NREP/TGFBR1/JUN/PARP1/HSPA1A/LRP2/ID1/PDCD4 14 GO:0071800 podosome assembly 3/320 18/18722 0.003336460951046 0.0270849835947389 LCP1/MSN/RHOA 3 GO:0010634 positive regulation of epithelial cell migration 9/320 176/18722 0.0033495932608255 0.0271382732426097 TMSB4X/NRP2/ANXA1/HMGB1/PFN1/HMOX1/PLPP3/HSPB1/PDCD6 9 GO:0045069 regulation of viral genome replication 6/320 85/18722 0.00335756193684091 0.0271496006321461 IFITM2/MX1/APOBEC3A/BST2/ISG15/TOP2A 6 GO:0002685 regulation of leukocyte migration 10/320 210/18722 0.00339256813211355 0.0273790850036976 AIF1/MSN/CCL3/ANXA1/PGF/CD99/HMGB1/CD74/HMOX1/RHOA 10 GO:0019693 ribose phosphate metabolic process 15/320 396/18722 0.00352541918671195 0.0283957740341009 GAPDH/CROT/TMSB4X/LDHA/ALDOA/UPP1/PKM/TPI1/ENO1/PYGL/PDE4B/PARP1/PGK1/PPT1/RHOA 15 GO:0045730 respiratory burst 4/320 37/18722 0.00354673308896407 0.0285118698902715 NCF2/CYBB/NCF1/CYBA 4 GO:0060761 negative regulation of response to cytokine stimulus 6/320 86/18722 0.00355868300496583 0.0285523848087744 PTPRC/CAV1/ISG15/SAMHD1/PARP14/CARD16 6 GO:0051262 protein tetramerization 6/320 87/18722 0.00376862106330764 0.0301781826232309 ALDOA/HLA-DRB1/SAMHD1/SOD2/B2M/VASP 6 GO:0051283 negative regulation of sequestering of calcium ion 7/320 116/18722 0.00380418097919573 0.030345320088874 PTPRC/CORO1A/CCL3/CYBA/SRI/ANXA6/GSTO1 7 GO:1990748 cellular detoxification 7/320 116/18722 0.00380418097919573 0.030345320088874 GPX3/GPX1/SOD2/GSTO1/GPX4/S100A9/SOD3 7 GO:0030865 cortical cytoskeleton organization 5/320 61/18722 0.00384760135811372 0.0305149497345986 PLEK/LCP1/EZR/PLEC/RHOA 5 GO:0034113 heterotypic cell-cell adhesion 5/320 61/18722 0.00384760135811372 0.0305149497345986 PTPRC/ITGB2/MYADM/DSP/ITGB1 5 GO:0071384 cellular response to corticosteroid stimulus 5/320 61/18722 0.00384760135811372 0.0305149497345986 ZFP36/ANXA1/ISL1/ATP2B1/ZFP36L2 5 GO:0051090 regulation of DNA-binding transcription factor activity 16/320 440/18722 0.00389875092003368 0.0306171378324366 TMSB4X/FLNA/CAV1/ANXA4/MTDH/BHLHE40/SRI/HMOX1/S100A9/HSPA1A/PLPP3/ID1/EZH2/CARD16/CTNNB1/TFRC 16 GO:0009595 detection of biotic stimulus 4/320 38/18722 0.00391144029136735 0.0306171378324366 HLA-A/HLA-B/TSPO/HLA-DRB1 4 GO:0002888 positive regulation of myeloid leukocyte mediated immunity 3/320 19/18722 0.00391235449552917 0.0306171378324366 ITGB2/TYROBP/HLA-E 3 GO:0033194 response to hydroperoxide 3/320 19/18722 0.00391235449552917 0.0306171378324366 GPX3/AIF1/GPX1 3 GO:0045019 negative regulation of nitric oxide biosynthetic process 3/320 19/18722 0.00391235449552917 0.0306171378324366 TSPO/CAV1/DYNLL1 3 GO:0046794 transport of virus 3/320 19/18722 0.00391235449552917 0.0306171378324366 BST2/CAV1/CTSL 3 GO:1904406 negative regulation of nitric oxide metabolic process 3/320 19/18722 0.00391235449552917 0.0306171378324366 TSPO/CAV1/DYNLL1 3 GO:0051384 response to glucocorticoid 8/320 148/18722 0.00398493245047628 0.0309785116110183 AIF1/ZFP36/ANXA1/ISL1/ATP2B1/HMGB1/ZFP36L2/RHOA 8 GO:0009144 purine nucleoside triphosphate metabolic process 6/320 88/18722 0.00398760706494275 0.0309785116110183 TMSB4X/ALDOA/SAMHD1/ENO1/PARP1/RHOA 6 GO:0002702 positive regulation of production of molecular mediator of immune response 7/320 117/18722 0.00398852085601688 0.0309785116110183 PTPRC/HLA-A/LAPTM5/HLA-E/CD74/B2M/TFRC 7 GO:0072676 lymphocyte migration 7/320 117/18722 0.00398852085601688 0.0309785116110183 AIF1/CCL3L3/MSN/CCL3/CD99/PLEC/RHOA 7 GO:0002260 lymphocyte homeostasis 5/320 62/18722 0.00412771893717073 0.0318798778474569 TSC22D3/TNFSF13B/CORO1A/PMAIP1/CD74 5 GO:0045428 regulation of nitric oxide biosynthetic process 5/320 62/18722 0.00412771893717073 0.0318798778474569 AIF1/TSPO/CAV1/KLF2/DYNLL1 5 GO:0046847 filopodium assembly 5/320 62/18722 0.00412771893717073 0.0318798778474569 EZR/RAB17/CDC42/TGFBR1/CAPZB 5 GO:0002377 immunoglobulin production 10/320 216/18722 0.00413925580673693 0.0319093376743228 PTPRC/HLA-DMA/HLA-DPA1/HLA-DRB1/HLA-DRA/HLA-DPB1/HLA-E/SAMHD1/B2M/TFRC 10 GO:0051282 regulation of sequestering of calcium ion 7/320 118/18722 0.00417955618660323 0.0321600114768055 PTPRC/CORO1A/CCL3/CYBA/SRI/ANXA6/GSTO1 7 GO:1900407 regulation of cellular response to oxidative stress 6/320 89/18722 0.00421587258321164 0.0323791552301682 PAGE4/GPX1/SOD2/PARP1/HSPB1/CTNNB1 6 GO:1903115 regulation of actin filament-based movement 4/320 39/18722 0.00430071116019668 0.0329084046554309 CAV1/DSP/SRI/PDE4B 4 GO:2000249 regulation of actin cytoskeleton reorganization 4/320 39/18722 0.00430071116019668 0.0329084046554309 GMFG/ARHGDIB/CDC42/IQGAP2 4 GO:0007163 establishment or maintenance of cell polarity 10/320 218/18722 0.00441510938103788 0.0336503093010277 MSN/CDC42/ITGB1/MYH9/CLIC4/DST/ACTR3/RHOA/ACTB/GJA1 10 GO:0030239 myofibril assembly 5/320 63/18722 0.00442210018162102 0.0336503093010277 KRT19/KRT8/ACTG1/ITGB1/PLEC 5 GO:0050854 regulation of antigen receptor-mediated signaling pathway 5/320 63/18722 0.00442210018162102 0.0336503093010277 PTPRC/LAPTM5/EZR/GBP1/SLC39A10 5 GO:0030901 midbrain development 6/320 90/18722 0.0044536496751836 0.0337660191887315 WLS/DYNLL1/CDC42/RHOA/ACTB/CTNNB1 6 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 6/320 90/18722 0.0044536496751836 0.0337660191887315 SOD2/JUN/HMOX1/RHOA/PDCD4/GJA1 6 GO:0002577 regulation of antigen processing and presentation 3/320 20/18722 0.00454509097211985 0.0340840578889278 FGL2/CD68/CD74 3 GO:0003159 morphogenesis of an endothelium 3/320 20/18722 0.00454509097211985 0.0340840578889278 CXCR4/RHOA/CTNNB1 3 GO:0032930 positive regulation of superoxide anion generation 3/320 20/18722 0.00454509097211985 0.0340840578889278 ITGB2/TYROBP/CYBA 3 GO:0061154 endothelial tube morphogenesis 3/320 20/18722 0.00454509097211985 0.0340840578889278 CXCR4/RHOA/CTNNB1 3 GO:0098543 detection of other organism 3/320 20/18722 0.00454509097211985 0.0340840578889278 HLA-A/HLA-B/HLA-DRB1 3 GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 3/320 20/18722 0.00454509097211985 0.0340840578889278 GPX1/SOD2/HSPB1 3 GO:0007052 mitotic spindle organization 7/320 120/18722 0.00458232332437128 0.0341771840727475 FLNA/NEK6/CCSAP/STMN1/SPC25/HSPA1A/RHOA 7 GO:0030218 erythrocyte differentiation 7/320 120/18722 0.00458232332437128 0.0341771840727475 ISG15/KLF2/ZFP36/B2M/STAT1/UBA5/HSPA1A 7 GO:0051897 positive regulation of protein kinase B signaling 7/320 120/18722 0.00458232332437128 0.0341771840727475 IGF2/CCL3/GPX1/MTDH/ITGB1/TGFBR1/LRP2 7 GO:1903362 regulation of cellular protein catabolic process 11/320 255/18722 0.00459196550914267 0.0341873900608604 LAPTM5/CAV1/MSN/EZR/RPL23/GPX1/DDA1/PTTG1IP/HSPA1A/PBK/LRP2 11 GO:0070371 ERK1 and ERK2 cascade 13/320 330/18722 0.00463829797579174 0.0343568379931709 PTPRC/CCL3L3/FN1/HLA-DRB1/CCL3/EZR/FBLN1/HMGB1/TIMP3/ZFP36L2/CD74/GBP1/CDK1 13 GO:0002040 sprouting angiogenesis 9/320 185/18722 0.00464442380563301 0.0343568379931709 PKM/KLF2/ANXA1/PGF/CDC42/HMGB1/ITGB1/HMOX1/RHOA 9 GO:0051492 regulation of stress fiber assembly 6/320 91/18722 0.0047011707454276 0.0343568379931709 ACTG1/CDC42/PFN1/STMN1/TGFBR1/RHOA 6 GO:1990874 vascular associated smooth muscle cell proliferation 6/320 91/18722 0.0047011707454276 0.0343568379931709 SOD2/JUN/HMOX1/RHOA/PDCD4/GJA1 6 GO:0030866 cortical actin cytoskeleton organization 4/320 40/18722 0.00471528855953141 0.0343568379931709 PLEK/LCP1/EZR/PLEC 4 GO:0045740 positive regulation of DNA replication 4/320 40/18722 0.00471528855953141 0.0343568379931709 CDC42/JUN/CDK1/DBF4 4 GO:0071276 cellular response to cadmium ion 4/320 40/18722 0.00471528855953141 0.0343568379931709 CYBB/NCF1/JUN/HMOX1 4 GO:1903522 regulation of blood circulation 11/320 256/18722 0.00472717881477595 0.0343568379931709 CYP2J2/FLNA/CAV1/DSP/ISL1/ATP2B1/SRI/PDE4B/GSTO1/RHOA/GJA1 11 GO:0001885 endothelial cell development 5/320 64/18722 0.00473113282142165 0.0343568379931709 MYADM/MSN/EZR/GPX1/CLIC4 5 GO:0006749 glutathione metabolic process 5/320 64/18722 0.00473113282142165 0.0343568379931709 CLIC3/GPX1/GSTO1/GPX4/IDH1 5 GO:0045670 regulation of osteoclast differentiation 5/320 64/18722 0.00473113282142165 0.0343568379931709 TYROBP/CCL3/FBN1/CTNNB1/CEBPB 5 GO:0055002 striated muscle cell development 5/320 64/18722 0.00473113282142165 0.0343568379931709 KRT19/KRT8/ACTG1/ITGB1/PLEC 5 GO:0080164 regulation of nitric oxide metabolic process 5/320 64/18722 0.00473113282142165 0.0343568379931709 AIF1/TSPO/CAV1/KLF2/DYNLL1 5 GO:1903409 reactive oxygen species biosynthetic process 5/320 64/18722 0.00473113282142165 0.0343568379931709 NCF1/PAGE4/CYBA/SOD2/RHOA 5 GO:0005996 monosaccharide metabolic process 11/320 257/18722 0.00486553403529949 0.0352708537436097 GAPDH/ALDOA/IGF2/SLC2A3/TPI1/ENO1/PMAIP1/PHLDA2/HMGB1/PGK1/GSTO1 11 GO:0009896 positive regulation of catabolic process 17/320 492/18722 0.00494566531925509 0.0357889476342593 TNFRSF1B/LAPTM5/CAV1/MSN/EZR/ZFP36/MTDH/BNIP3L/OAZ1/HMGB1/DDA1/ZFP36L2/PTTG1IP/HMOX1/HSPA1A/LRP2/GJA1 17 GO:0050868 negative regulation of T cell activation 7/320 122/18722 0.00501370909031249 0.036154704993318 FGL2/LAPTM5/HLA-DRB1/ANXA1/HMGB1/CD74/CEBPB 7 GO:0051208 sequestering of calcium ion 7/320 122/18722 0.00501370909031249 0.036154704993318 PTPRC/CORO1A/CCL3/CYBA/SRI/ANXA6/GSTO1 7 GO:0002720 positive regulation of cytokine production involved in immune response 5/320 65/18722 0.00505520246586301 0.036390412175864 HLA-A/LAPTM5/HLA-E/CD74/B2M 5 GO:0045927 positive regulation of growth 11/320 259/18722 0.00515187249317969 0.0370218037249017 IGF2/CXCR4/FN1/CYBA/EZR/CDC42/TGFBR1/CDK1/S100A9/RHOA/YBX3 11 GO:0032755 positive regulation of interleukin-6 production 6/320 93/18722 0.00522637536229969 0.0371115610004016 AIF1/TYROBP/CYBA/ISL1/HMGB1/CD74 6 GO:0035455 response to interferon-alpha 3/320 21/18722 0.00523621492333836 0.0371115610004016 IFITM2/BST2/IFIT2 3 GO:0044766 multi-organism transport 3/320 21/18722 0.00523621492333836 0.0371115610004016 BST2/CAV1/CTSL 3 GO:0045655 regulation of monocyte differentiation 3/320 21/18722 0.00523621492333836 0.0371115610004016 HLA-DRB1/JUN/CD74 3 GO:0046641 positive regulation of alpha-beta T cell proliferation 3/320 21/18722 0.00523621492333836 0.0371115610004016 PTPRC/HLA-A/HLA-E 3 GO:0048485 sympathetic nervous system development 3/320 21/18722 0.00523621492333836 0.0371115610004016 NRP2/CTNNB1/SOX4 3 GO:0071498 cellular response to fluid shear stress 3/320 21/18722 0.00523621492333836 0.0371115610004016 KLF2/PLEC/TFPI2 3 GO:1902579 multi-organism localization 3/320 21/18722 0.00523621492333836 0.0371115610004016 BST2/CAV1/CTSL 3 GO:0034614 cellular response to reactive oxygen species 8/320 155/18722 0.00525542365908772 0.0371203599305136 NCF1/KLF2/ANXA1/SOD2/JUN/CDK1/SOD3/EZH2 8 GO:1903364 positive regulation of cellular protein catabolic process 8/320 155/18722 0.00525542365908772 0.0371203599305136 LAPTM5/CAV1/MSN/EZR/DDA1/PTTG1IP/HSPA1A/LRP2 8 GO:0002253 activation of immune response 14/320 375/18722 0.00537751006422368 0.0379178695996114 PTPRC/MNDA/HLA-A/FCN1/TYROBP/LAPTM5/FCER1G/HLA-DRB1/EZR/HLA-DPB1/HMGB1/PDE4B/GBP1/SLC39A10 14 GO:0009132 nucleoside diphosphate metabolic process 7/320 124/18722 0.00547494912508165 0.0384736220830568 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGK1 7 GO:0097237 cellular response to toxic substance 7/320 124/18722 0.00547494912508165 0.0384736220830568 GPX3/GPX1/SOD2/GSTO1/GPX4/S100A9/SOD3 7 GO:0032091 negative regulation of protein binding 6/320 94/18722 0.00550452423633413 0.0386157795323134 CAV1/B2M/IFIT2/ID1/ACTB/CARD16 6 GO:0014912 negative regulation of smooth muscle cell migration 4/320 42/18722 0.00562325354989354 0.0392487899800002 AIF1/IGFBP3/SEMA6D/RHOA 4 GO:0030574 collagen catabolic process 4/320 42/18722 0.00562325354989354 0.0392487899800002 CTSS/ITGB1/CTSB/CTSL 4 GO:0046596 regulation of viral entry into host cell 4/320 42/18722 0.00562325354989354 0.0392487899800002 IFITM2/FCN1/HLA-DRB1/CD74 4 GO:0050821 protein stabilization 9/320 191/18722 0.00570397782250377 0.0397450866148155 GAPDH/FLNA/TYROBP/RPL23/IFI30/PFN1/HSPA1A/PLPP3/SOX4 9 GO:0006942 regulation of striated muscle contraction 6/320 95/18722 0.00579334747514115 0.0401646170592 CAV1/C12orf57/DSP/SRI/PDE4B/GSTO1 6 GO:0007044 cell-substrate junction assembly 6/320 95/18722 0.00579334747514115 0.0401646170592 FN1/ACTG1/PLEC/DST/PTPRA/RHOA 6 GO:0036473 cell death in response to oxidative stress 6/320 95/18722 0.00579334747514115 0.0401646170592 PAGE4/GPX1/SOD2/PARP1/HSPB1/CTNNB1 6 GO:0030198 extracellular matrix organization 12/320 301/18722 0.00584358641873285 0.0404450570891192 TNFRSF1B/CTSS/CAV1/P4HA1/LCP1/CCDC80/FBLN1/COL14A1/ADAMTSL4/ITGB1/TGFBR1/ADAMTS6 12 GO:0006907 pinocytosis 3/320 22/18722 0.00598714036527426 0.0410803127819561 CAV1/CDC42/PPT1 3 GO:0035089 establishment of apical/basal cell polarity 3/320 22/18722 0.00598714036527426 0.0410803127819561 MSN/CDC42/RHOA 3 GO:0050860 negative regulation of T cell receptor signaling pathway 3/320 22/18722 0.00598714036527426 0.0410803127819561 LAPTM5/EZR/GBP1 3 GO:0051220 cytoplasmic sequestering of protein 3/320 22/18722 0.00598714036527426 0.0410803127819561 TMSB4X/FLNA/SRI 3 GO:0071404 cellular response to low-density lipoprotein particle stimulus 3/320 22/18722 0.00598714036527426 0.0410803127819561 ITGB2/FCER1G/ITGB1 3 GO:0043062 extracellular structure organization 12/320 302/18722 0.00599502144422061 0.0410803127819561 TNFRSF1B/CTSS/CAV1/P4HA1/LCP1/CCDC80/FBLN1/COL14A1/ADAMTSL4/ITGB1/TGFBR1/ADAMTS6 12 GO:0006509 membrane protein ectodomain proteolysis 4/320 43/18722 0.00611804395614259 0.0415333918574717 TNFRSF1B/TIMP2/TIMP3/MYH9 4 GO:0098927 vesicle-mediated transport between endosomal compartments 4/320 43/18722 0.00611804395614259 0.0415333918574717 FLNA/CORO1A/MSN/EZR 4 GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation 4/320 43/18722 0.00611804395614259 0.0415333918574717 SOD2/HMOX1/RHOA/PDCD4 4 GO:0032922 circadian regulation of gene expression 5/320 68/18722 0.00612145102642794 0.0415333918574717 BHLHE40/NAMPT/BHLHE41/MAGED1/ID1 5 GO:0046637 regulation of alpha-beta T cell differentiation 5/320 68/18722 0.00612145102642794 0.0415333918574717 HLA-DRB1/HLA-DRA/ANXA1/HMGB1/RHOA 5 GO:0060411 cardiac septum morphogenesis 5/320 68/18722 0.00612145102642794 0.0415333918574717 NRP2/ISL1/TGFBR1/LRP2/SOX4 5 GO:0033157 regulation of intracellular protein transport 10/320 229/18722 0.0062014425406882 0.0420071484887273 ITGB2/FLNA/LCP1/BNIP3L/OAZ1/CDC42/ICE1/TCAF1/CDK1/UBE2J1 10 GO:1901654 response to ketone 9/320 194/18722 0.00629928805279364 0.0425840711276853 TXNIP/CYBB/TSPO/CAV1/MSN/CYBA/KLF2/ATP2B1/PARP1 9 GO:0045229 external encapsulating structure organization 12/320 304/18722 0.00630722447486529 0.0425840711276853 TNFRSF1B/CTSS/CAV1/P4HA1/LCP1/CCDC80/FBLN1/COL14A1/ADAMTSL4/ITGB1/TGFBR1/ADAMTS6 12 GO:0035637 multicellular organismal signaling 8/320 160/18722 0.00633741114715555 0.0427180797064384 FLNA/CAV1/DSP/ISL1/ATP2B1/SRI/PLEC/GJA1 8 GO:0070252 actin-mediated cell contraction 6/320 97/18722 0.00640394506307311 0.0430962557013324 FLNA/CAV1/DSP/SRI/PDE4B/GJA1 6 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 7/320 128/18722 0.00649196712688322 0.0436175742573682 PEG10/ZEB2/CAV1/HTRA1/FBN1/NREP/HSPA1A 7 GO:0003205 cardiac chamber development 8/320 161/18722 0.0065727023073908 0.0440883213216539 NRP2/LMO4/DSP/ISL1/TGFBR1/ADAMTS6/LRP2/SOX4 8 GO:0001894 tissue homeostasis 11/320 268/18722 0.00660946617966245 0.0441163760824024 LYZ/CORO1A/ACTG1/ITGB1/B2M/SNX10/ACTB/HSPB1/CTNNB1/GJA1/TFRC 11 GO:0050708 regulation of protein secretion 11/320 268/18722 0.00660946617966245 0.0441163760824024 HLA-DRB1/EZR/ANXA1/WLS/DYNLL1/ISL1/SRI/HMGN3/MYH10/SOX4/GJA1 11 GO:0021762 substantia nigra development 4/320 44/18722 0.00664094528636357 0.0441163760824024 DYNLL1/CDC42/RHOA/ACTB 4 GO:0042269 regulation of natural killer cell mediated cytotoxicity 4/320 44/18722 0.00664094528636357 0.0441163760824024 SERPINB9/HLA-A/HLA-B/HLA-E 4 GO:0062208 positive regulation of pattern recognition receptor signaling pathway 4/320 44/18722 0.00664094528636357 0.0441163760824024 CAV1/CYBA/HMGB1/HSPA1A 4 GO:0150076 neuroinflammatory response 4/320 44/18722 0.00664094528636357 0.0441163760824024 PTPRC/TNFRSF1B/CCL3/ITGB1 4 GO:0022408 negative regulation of cell-cell adhesion 9/320 196/18722 0.00672197246978761 0.0444078801999114 FGL2/FXYD5/MYADM/LAPTM5/HLA-DRB1/ANXA1/HMGB1/CD74/CEBPB 9 GO:0043393 regulation of protein binding 9/320 196/18722 0.00672197246978761 0.0444078801999114 CAV1/PHLDA2/CDC42/TGFBR1/B2M/IFIT2/ID1/ACTB/CARD16 9 GO:1902882 regulation of response to oxidative stress 6/320 98/18722 0.00672618214818793 0.0444078801999114 PAGE4/GPX1/SOD2/PARP1/HSPB1/CTNNB1 6 GO:0009259 ribonucleotide metabolic process 14/320 385/18722 0.0067278153449043 0.0444078801999114 GAPDH/CROT/TMSB4X/LDHA/ALDOA/UPP1/PKM/TPI1/ENO1/PDE4B/PARP1/PGK1/PPT1/RHOA 14 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 7/320 129/18722 0.0067668274542851 0.0445941483909187 TNFSF10/LAPTM5/PMAIP1/HMGB1/S100A9/RHOA/PDCD6 7 GO:2001169 regulation of ATP biosynthetic process 3/320 23/18722 0.00679915580051589 0.0447358467639039 TMSB4X/ENO1/PARP1 3 GO:0071248 cellular response to metal ion 9/320 197/18722 0.00694131286120638 0.0455985766971459 CYBB/NCF1/TSPO/FUS/JUN/CLIC4/B2M/PARP1/HMOX1 9 GO:0031331 positive regulation of cellular catabolic process 15/320 427/18722 0.0069632391278494 0.0456700064702758 TNFRSF1B/LAPTM5/CAV1/MSN/EZR/ZFP36/MTDH/BNIP3L/HMGB1/DDA1/ZFP36L2/PTTG1IP/HMOX1/HSPA1A/LRP2 15 GO:0050864 regulation of B cell activation 9/320 198/18722 0.00716609932314252 0.0469260259956021 PTPRC/MNDA/TNFSF13B/TYROBP/LAPTM5/ZFP36L2/CD74/SLC39A10/TFRC 9 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 4/320 45/18722 0.00719261377586442 0.0470251267751136 GPX1/SOD2/PARP1/HSPB1 4 GO:0050680 negative regulation of epithelial cell proliferation 8/320 164/18722 0.00731838874303192 0.047702313128305 CAV1/ISL1/FLT1/TGFBR1/B2M/STAT1/MAGED1/GJA1 8 GO:0051047 positive regulation of secretion 12/320 310/18722 0.0073216565998139 0.047702313128305 ITGB2/HLA-DRB1/CYBA/EZR/CYP19A1/WLS/DYNLL1/ISL1/SRI/MYH10/SOX4/GJA1 12 GO:0003208 cardiac ventricle morphogenesis 5/320 71/18722 0.0073366451709194 0.047702313128305 DSP/ISL1/TGFBR1/LRP2/SOX4 5 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 7/320 131/18722 0.00734236959090077 0.047702313128305 PEG10/ZEB2/CAV1/HTRA1/FBN1/NREP/HSPA1A 7 GO:0110020 regulation of actomyosin structure organization 6/320 100/18722 0.00740568456086744 0.0480381296789706 ACTG1/CDC42/PFN1/STMN1/TGFBR1/RHOA 6 GO:0040013 negative regulation of locomotion 14/320 391/18722 0.00766000050975728 0.0490814380275783 AIF1/BST2/ARHGDIB/FBLN1/ARRDC3/HMGB1/IGFBP3/CD74/CLIC4/SEMA6D/TCAF1/HMOX1/RHOA/GJA1 14 GO:0003148 outflow tract septum morphogenesis 3/320 24/18722 0.00767342908175595 0.0490814380275783 NRP2/ISL1/LRP2 3 GO:0030859 polarized epithelial cell differentiation 3/320 24/18722 0.00767342908175595 0.0490814380275783 MSN/CDC42/RHOA 3 GO:0031639 plasminogen activation 3/320 24/18722 0.00767342908175595 0.0490814380275783 ENO1/DHCR24/PGK1 3 GO:0032928 regulation of superoxide anion generation 3/320 24/18722 0.00767342908175595 0.0490814380275783 ITGB2/TYROBP/CYBA 3 GO:0035458 cellular response to interferon-beta 3/320 24/18722 0.00767342908175595 0.0490814380275783 MNDA/IFITM2/STAT1 3 GO:0048641 regulation of skeletal muscle tissue development 3/320 24/18722 0.00767342908175595 0.0490814380275783 IGF2/YBX3/CTNNB1 3 GO:0051043 regulation of membrane protein ectodomain proteolysis 3/320 24/18722 0.00767342908175595 0.0490814380275783 TNFRSF1B/TIMP2/TIMP3 3 GO:0061162 establishment of monopolar cell polarity 3/320 24/18722 0.00767342908175595 0.0490814380275783 MSN/CDC42/RHOA 3 GO:0150115 cell-substrate junction organization 6/320 101/18722 0.00776340794234907 0.049434786652756 FN1/ACTG1/PLEC/DST/PTPRA/RHOA 6 GO:0055010 ventricular cardiac muscle tissue morphogenesis 4/320 46/18722 0.00777368666549902 0.049434786652756 DSP/ISL1/TGFBR1/LRP2 4 GO:0005977 glycogen metabolic process 5/320 72/18722 0.00777652742601438 0.049434786652756 IGF2/PYGL/PHLDA2/HMGB1/UGP2 5 GO:0043903 regulation of biological process involved in symbiotic interaction 5/320 72/18722 0.00777652742601438 0.049434786652756 IFITM2/FCN1/CAV1/HLA-DRB1/CD74 5 GO:0043112 receptor metabolic process 8/320 166/18722 0.00784982230562878 0.0498240641580002 ITGB2/LAPTM5/FCER1G/CAV1/EZR/CD63/ITGB1/TFRC 8 GO:0046887 positive regulation of hormone secretion 7/320 133/18722 0.00795338250963221 0.0504039517328225 HLA-DRB1/CYP19A1/DYNLL1/ISL1/SRI/SOX4/GJA1 7 GO:0051259 protein complex oligomerization 10/320 238/18722 0.00804457403050481 0.0509037976937915 ALDOA/HLA-DRB1/ISG15/FUS/KCTD12/SAMHD1/SOD2/CD74/B2M/VASP 10 GO:0009913 epidermal cell differentiation 9/320 202/18722 0.00812142456952298 0.05118497490799 TXNIP/ZFP36/ANXA1/DSP/FLNB/CLIC4/PLEC/EZH2/CTNNB1 9 GO:0032388 positive regulation of intracellular transport 9/320 202/18722 0.00812142456952298 0.05118497490799 ITGB2/FLNA/MSN/EZR/OAZ1/CDC42/ICE1/TCAF1/CDK1 9 GO:0034767 positive regulation of ion transmembrane transport 8/320 167/18722 0.00812617220223655 0.05118497490799 TMSB4X/CTSS/FLNA/SRI/ITGB1/IFNGR2/TCAF1/GSTO1 8 GO:0006073 cellular glucan metabolic process 5/320 73/18722 0.00823441842317253 0.0516306781859619 IGF2/PYGL/PHLDA2/HMGB1/UGP2 5 GO:0043299 leukocyte degranulation 5/320 73/18722 0.00823441842317253 0.0516306781859619 ITGB2/CORO1A/CCL3/HMOX1/STXBP2 5 GO:0044042 glucan metabolic process 5/320 73/18722 0.00823441842317253 0.0516306781859619 IGF2/PYGL/PHLDA2/HMGB1/UGP2 5 GO:0042311 vasodilation 4/320 47/18722 0.00838478176537822 0.0521775877327452 GPX1/KLF2/SOD2/GJA1 4 GO:0045581 negative regulation of T cell differentiation 4/320 47/18722 0.00838478176537822 0.0521775877327452 FGL2/ANXA1/HMGB1/CD74 4 GO:0045911 positive regulation of DNA recombination 4/320 47/18722 0.00838478176537822 0.0521775877327452 PTPRC/FUS/PARP1/TFRC 4 GO:0048483 autonomic nervous system development 4/320 47/18722 0.00838478176537822 0.0521775877327452 FN1/NRP2/CTNNB1/SOX4 4 GO:0051489 regulation of filopodium assembly 4/320 47/18722 0.00838478176537822 0.0521775877327452 RAB17/CDC42/TGFBR1/CAPZB 4 GO:0050851 antigen receptor-mediated signaling pathway 10/320 240/18722 0.00850617392912684 0.0523245619426739 PTPRC/MNDA/HLA-A/LAPTM5/HLA-DRB1/EZR/HLA-DPB1/PDE4B/GBP1/SLC39A10 10 GO:0006163 purine nucleotide metabolic process 14/320 396/18722 0.00851287558642654 0.0523245619426739 GAPDH/CROT/TMSB4X/LDHA/ALDOA/PKM/TPI1/SAMHD1/ENO1/PDE4B/PARP1/PGK1/PPT1/RHOA 14 GO:0014013 regulation of gliogenesis 6/320 103/18722 0.00851593615310122 0.0523245619426739 TNFRSF1B/TSPO/CXCR4/LRP2/EZH2/CTNNB1 6 GO:0090277 positive regulation of peptide hormone secretion 6/320 103/18722 0.00851593615310122 0.0523245619426739 HLA-DRB1/DYNLL1/ISL1/SRI/SOX4/GJA1 6 GO:0031349 positive regulation of defense response 11/320 278/18722 0.0085887650588521 0.0523245619426739 MNDA/FCN1/TYROBP/CCL3/CYBA/HLA-E/HMGB1/S100A9/PDCD4/GJA1/CEBPB 11 GO:0001101 response to acid chemical 7/320 135/18722 0.00860111459023079 0.0523245619426739 CYBB/KRT8/CYBA/KLF2/PLEC/RHOA/CEBPB 7 GO:0002687 positive regulation of leukocyte migration 7/320 135/18722 0.00860111459023079 0.0523245619426739 AIF1/CCL3/PGF/CD99/HMGB1/CD74/RHOA 7 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 3/320 25/18722 0.00861101212996569 0.0523245619426739 CYBA/RHOA/GJA1 3 GO:0032753 positive regulation of interleukin-4 production 3/320 25/18722 0.00861101212996569 0.0523245619426739 FCER1G/HLA-E/CEBPB 3 GO:0045109 intermediate filament organization 3/320 25/18722 0.00861101212996569 0.0523245619426739 VIM/DSP/PLEC 3 GO:0061339 establishment or maintenance of monopolar cell polarity 3/320 25/18722 0.00861101212996569 0.0523245619426739 MSN/CDC42/RHOA 3 GO:0086064 cell communication by electrical coupling involved in cardiac conduction 3/320 25/18722 0.00861101212996569 0.0523245619426739 CAV1/SRI/GJA1 3 GO:0098581 detection of external biotic stimulus 3/320 25/18722 0.00861101212996569 0.0523245619426739 HLA-A/HLA-B/HLA-DRB1 3 GO:1901798 positive regulation of signal transduction by p53 class mediator 3/320 25/18722 0.00861101212996569 0.0523245619426739 RPL23/RPL37/PMAIP1 3 GO:1903901 negative regulation of viral life cycle 3/320 25/18722 0.00861101212996569 0.0523245619426739 IFITM2/FCN1/BST2 3 GO:1903959 regulation of anion transmembrane transport 3/320 25/18722 0.00861101212996569 0.0523245619426739 ITGB1/SLC43A2/TCAF1 3 GO:0071383 cellular response to steroid hormone stimulus 9/320 204/18722 0.0086340033679908 0.052387227483903 LBH/ZFP36/ANXA1/ISL1/ATP2B1/ZFP36L2/PARP1/UBA5/RHOA 9 GO:0002437 inflammatory response to antigenic stimulus 5/320 74/18722 0.00871067123430245 0.05269764793578 HLA-DRB1/CD68/GPX1/HLA-E/HMGB1 5 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 5/320 74/18722 0.00871067123430245 0.05269764793578 LBH/ISL1/PARP1/UBA5/RHOA 5 GO:0043410 positive regulation of MAPK cascade 16/320 480/18722 0.00874779983943946 0.0528448961060875 PTPRC/IGF2/NCF1/CCL3L3/LAPTM5/HLA-DRB1/CCL3/TIMP2/CDC42/HMGB1/FLT1/TGFBR1/CD74/MAGED1/EZH2/CTNNB1 16 GO:0002715 regulation of natural killer cell mediated immunity 4/320 48/18722 0.00902649706550975 0.0543695129368605 SERPINB9/HLA-A/HLA-B/HLA-E 4 GO:0090199 regulation of release of cytochrome c from mitochondria 4/320 48/18722 0.00902649706550975 0.0543695129368605 TNFSF10/PLAUR/GPX1/PMAIP1 4 GO:0016049 cell growth 16/320 482/18722 0.00908002701827995 0.0546123313530317 BST2/CXCR4/FN1/NRP2/CYBA/ENO1/CDC42/ITGB1/TGFBR1/SEMA6D/S100A9/HSPA1A/PPT1/RHOA/CTNNB1/GJA1 16 GO:2000146 negative regulation of cell motility 13/320 359/18722 0.00914552027212698 0.054926293262251 AIF1/BST2/ARHGDIB/FBLN1/HMGB1/IGFBP3/CD74/CLIC4/SEMA6D/TCAF1/HMOX1/RHOA/GJA1 13 GO:0033077 T cell differentiation in thymus 5/320 75/18722 0.00920563397729816 0.0551059221936541 PTPRC/ZFP36L2/CD74/B2M/CTNNB1 5 GO:0043627 response to estrogen 5/320 75/18722 0.00920563397729816 0.0551059221936541 KRT19/SERPINB9/LDHA/CAV1/HMOX1 5 GO:0045936 negative regulation of phosphate metabolic process 15/320 441/18722 0.00921543858562802 0.0551059221936541 PTPRC/PLEK/MYADM/CAV1/FBLN1/DYNLL1/PARP14/MLLT1/IGFBP3/PLEC/PARP1/PLPP3/PBK/HSPB1/PDCD4 15 GO:0009895 negative regulation of catabolic process 12/320 320/18722 0.00929329594978952 0.0554111094726267 TSPO/FLNA/RPL23/TIMP2/ZFP36/FUS/TIMP3/NAMPT/HMOX1/PBK/AZIN1/YBX3 12 GO:0071496 cellular response to external stimulus 12/320 320/18722 0.00929329594978952 0.0554111094726267 PTPRC/AIF1/UPP1/CD68/CYBA/PMAIP1/ATP2B1/JUN/PLEC/NAMPT/HMOX1/GJA1 12 GO:0040029 regulation of gene expression, epigenetic 6/320 105/18722 0.00931940761875178 0.055486732392914 IGF2/GPX1/KLF2/MBD3/CDCA4/EZH2 6 GO:0010563 negative regulation of phosphorus metabolic process 15/320 442/18722 0.0093961300625135 0.0558630351342529 PTPRC/PLEK/MYADM/CAV1/FBLN1/DYNLL1/PARP14/MLLT1/IGFBP3/PLEC/PARP1/PLPP3/PBK/HSPB1/PDCD4 15 GO:1903532 positive regulation of secretion by cell 11/320 282/18722 0.0094982070779333 0.056388781100604 ITGB2/HLA-DRB1/EZR/CYP19A1/WLS/DYNLL1/ISL1/SRI/MYH10/SOX4/GJA1 11 GO:0002418 immune response to tumor cell 3/320 26/18722 0.00961284551093678 0.0565295007654281 HLA-A/HLA-DRB1/HMGB1 3 GO:0046697 decidualization 3/320 26/18722 0.00961284551093678 0.0565295007654281 STC2/CTSB/GJA1 3 GO:0051016 barbed-end actin filament capping 3/320 26/18722 0.00961284551093678 0.0565295007654281 CAPG/CAPZA1/CAPZB 3 GO:0097066 response to thyroid hormone 3/320 26/18722 0.00961284551093678 0.0565295007654281 CTSS/CTSB/CTSL 3 GO:0055076 transition metal ion homeostasis 7/320 138/18722 0.00964428080308617 0.0565295007654281 FTH1/SRI/B2M/HMOX1/SLC39A10/S100A9/TFRC 7 GO:0010823 negative regulation of mitochondrion organization 4/320 49/18722 0.00969941039126404 0.0565295007654281 TSPO/GPX1/HSPA1A/TFRC 4 GO:0035088 establishment or maintenance of apical/basal cell polarity 4/320 49/18722 0.00969941039126404 0.0565295007654281 MSN/CDC42/CLIC4/RHOA 4 GO:0061245 establishment or maintenance of bipolar cell polarity 4/320 49/18722 0.00969941039126404 0.0565295007654281 MSN/CDC42/CLIC4/RHOA 4 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 4/320 49/18722 0.00969941039126404 0.0565295007654281 GPX1/PMAIP1/TIMP3/HMOX1 4 GO:0001937 negative regulation of endothelial cell proliferation 5/320 76/18722 0.00971964958026476 0.0565295007654281 CAV1/FLT1/TGFBR1/STAT1/GJA1 5 GO:0006809 nitric oxide biosynthetic process 5/320 76/18722 0.00971964958026476 0.0565295007654281 AIF1/TSPO/CAV1/KLF2/DYNLL1 5 GO:0043536 positive regulation of blood vessel endothelial cell migration 5/320 76/18722 0.00971964958026476 0.0565295007654281 TMSB4X/ANXA1/HMGB1/HMOX1/HSPB1 5 GO:2000379 positive regulation of reactive oxygen species metabolic process 5/320 76/18722 0.00971964958026476 0.0565295007654281 ITGB2/TSPO/TYROBP/CYBA/SOD2 5 GO:0002793 positive regulation of peptide secretion 6/320 106/18722 0.00974080458494307 0.0565295007654281 HLA-DRB1/DYNLL1/ISL1/SRI/SOX4/GJA1 6 GO:0030038 contractile actin filament bundle assembly 6/320 106/18722 0.00974080458494307 0.0565295007654281 ACTG1/CDC42/PFN1/STMN1/TGFBR1/RHOA 6 GO:0043149 stress fiber assembly 6/320 106/18722 0.00974080458494307 0.0565295007654281 ACTG1/CDC42/PFN1/STMN1/TGFBR1/RHOA 6 GO:0030216 keratinocyte differentiation 7/320 139/18722 0.0100117060554196 0.0579506511782212 TXNIP/ZFP36/ANXA1/DSP/FLNB/CLIC4/PLEC 7 GO:0031668 cellular response to extracellular stimulus 10/320 246/18722 0.010013737885104 0.0579506511782212 PTPRC/AIF1/UPP1/CD68/PMAIP1/ATP2B1/JUN/PLEC/NAMPT/HMOX1 10 GO:0006275 regulation of DNA replication 6/320 107/18722 0.0101756031246719 0.0588050239316701 CDC42/JUN/CDK1/RFC3/GMNN/DBF4 6 GO:0055117 regulation of cardiac muscle contraction 5/320 77/18722 0.0102530555545626 0.0591008935495679 CAV1/DSP/SRI/PDE4B/GSTO1 5 GO:0001659 temperature homeostasis 8/320 174/18722 0.0102697099633567 0.0591008935495679 PLAC8/CXCR4/CAV1/GPX1/ARRDC3/ID1/GJA1/CEBPB 8 GO:0007584 response to nutrient 8/320 174/18722 0.0102697099633567 0.0591008935495679 LDHA/CYBB/TSPO/SOD2/STC2/ATP2B1/STAT1/HMOX1 8 GO:0007623 circadian rhythm 9/320 210/18722 0.0103197336505966 0.0592414777939666 BHLHE40/JUN/NAMPT/CDK1/BHLHE41/MAGED1/ID1/EZH2/TOP2A 9 GO:0009117 nucleotide metabolic process 16/320 489/18722 0.0103228131683582 0.0592414777939666 GAPDH/CROT/TMSB4X/LDHA/ALDOA/UPP1/PKM/TPI1/SAMHD1/ENO1/NAMPT/PDE4B/PARP1/PGK1/PPT1/RHOA 16 GO:0045058 T cell selection 4/320 50/18722 0.0104040791016348 0.0593779763093304 PTPRC/CD74/CTSL/RHOA 4 GO:0046638 positive regulation of alpha-beta T cell differentiation 4/320 50/18722 0.0104040791016348 0.0593779763093304 HLA-DRB1/HLA-DRA/ANXA1/RHOA 4 GO:0060337 type I interferon signaling pathway 4/320 50/18722 0.0104040791016348 0.0593779763093304 IFITM2/ISG15/SAMHD1/STAT1 4 GO:2000677 regulation of transcription regulatory region DNA binding 4/320 50/18722 0.0104040791016348 0.0593779763093304 TMSB4X/SRI/PARP1/CTNNB1 4 GO:0060333 interferon-gamma-mediated signaling pathway 3/320 27/18722 0.0106797628738989 0.0607834437946973 PARP14/IFNGR2/STAT1 3 GO:1903319 positive regulation of protein maturation 3/320 27/18722 0.0106797628738989 0.0607834437946973 ENO1/MYH9/SOX4 3 GO:1903038 negative regulation of leukocyte cell-cell adhesion 7/320 141/18722 0.0107770324443207 0.0612498646984778 FGL2/LAPTM5/HLA-DRB1/ANXA1/HMGB1/CD74/CEBPB 7 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 5/320 78/18722 0.0108061837766676 0.0612498646984778 SERPINB9/PLAUR/GPX1/DHCR24/CARD16 5 GO:0070373 negative regulation of ERK1 and ERK2 cascade 5/320 78/18722 0.0108061837766676 0.0612498646984778 PTPRC/EZR/FBLN1/TIMP3/GBP1 5 GO:0051271 negative regulation of cellular component movement 13/320 367/18722 0.010855918975365 0.0614474756249424 AIF1/BST2/ARHGDIB/FBLN1/HMGB1/IGFBP3/CD74/CLIC4/SEMA6D/TCAF1/HMOX1/RHOA/GJA1 13 GO:0009150 purine ribonucleotide metabolic process 13/320 368/18722 0.0110861279474656 0.0625790719657485 GAPDH/CROT/TMSB4X/LDHA/ALDOA/PKM/TPI1/ENO1/PDE4B/PARP1/PGK1/PPT1/RHOA 13 GO:0071692 protein localization to extracellular region 13/320 368/18722 0.0110861279474656 0.0625790719657485 PLEK/HLA-DRB1/EZR/ANXA1/FBN1/WLS/DYNLL1/ISL1/SRI/HMGN3/MYH10/SOX4/GJA1 13 GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 4/320 51/18722 0.0111410398283326 0.0628032422519378 HLA-DRB1/HLA-DRA/ANXA1/HMGB1 4 GO:0001895 retina homeostasis 5/320 79/18722 0.0113793602788326 0.0640592870192594 LYZ/ACTG1/B2M/ACTB/HSPB1 5 GO:0034504 protein localization to nucleus 11/320 290/18722 0.0115385339449649 0.0648669690620341 TXNIP/FLNA/GBP2/RPL23/SYNE1/PTTG1IP/PARP1/PPP1R10/CDK1/MAGED1/TFRC 11 GO:0038061 NIK/NF-kappaB signaling 7/320 143/18722 0.0115840080180194 0.0649458902719893 TMSB4X/LAPTM5/LITAF/HMGB1/REL/RHOA/PDCD4 7 GO:0062013 positive regulation of small molecule metabolic process 7/320 143/18722 0.0115840080180194 0.0649458902719893 TMSB4X/IGF2/ANXA1/ENO1/PMAIP1/HMGB1/CD74 7 GO:0002507 tolerance induction 3/320 28/18722 0.011812495255832 0.0652610900020274 HLA-B/HLA-E/HMGB1 3 GO:0034123 positive regulation of toll-like receptor signaling pathway 3/320 28/18722 0.011812495255832 0.0652610900020274 CAV1/CYBA/HMGB1 3 GO:0045671 negative regulation of osteoclast differentiation 3/320 28/18722 0.011812495255832 0.0652610900020274 CCL3/FBN1/CTNNB1 3 GO:0061082 myeloid leukocyte cytokine production 3/320 28/18722 0.011812495255832 0.0652610900020274 LAPTM5/CD74/HMOX1 3 GO:0090200 positive regulation of release of cytochrome c from mitochondria 3/320 28/18722 0.011812495255832 0.0652610900020274 TNFSF10/PLAUR/PMAIP1 3 GO:1990776 response to angiotensin 3/320 28/18722 0.011812495255832 0.0652610900020274 CYBB/CAV1/CYBA 3 GO:0006753 nucleoside phosphate metabolic process 16/320 497/18722 0.0119043383634389 0.0652610900020274 GAPDH/CROT/TMSB4X/LDHA/ALDOA/UPP1/PKM/TPI1/SAMHD1/ENO1/NAMPT/PDE4B/PARP1/PGK1/PPT1/RHOA 16 GO:0002218 activation of innate immune response 4/320 52/18722 0.0119108082538158 0.0652610900020274 MNDA/FCN1/TYROBP/HMGB1 4 GO:0010718 positive regulation of epithelial to mesenchymal transition 4/320 52/18722 0.0119108082538158 0.0652610900020274 ISL1/TGFBR1/EZH2/CTNNB1 4 GO:0031103 axon regeneration 4/320 52/18722 0.0119108082538158 0.0652610900020274 TSPO/FLNA/ISL1/NREP 4 GO:0043277 apoptotic cell clearance 4/320 52/18722 0.0119108082538158 0.0652610900020274 FCN1/TYROBP/ANXA1/HMGB1 4 GO:0045010 actin nucleation 4/320 52/18722 0.0119108082538158 0.0652610900020274 GMFG/CORO1A/IQGAP2/ACTR3 4 GO:0071357 cellular response to type I interferon 4/320 52/18722 0.0119108082538158 0.0652610900020274 IFITM2/ISG15/SAMHD1/STAT1 4 GO:1903426 regulation of reactive oxygen species biosynthetic process 4/320 52/18722 0.0119108082538158 0.0652610900020274 PAGE4/CYBA/SOD2/RHOA 4 GO:0003056 regulation of vascular associated smooth muscle contraction 2/320 10/18722 0.0119700486165709 0.0652610900020274 ATP2B1/RHOA 2 GO:0021932 hindbrain radial glia guided cell migration 2/320 10/18722 0.0119700486165709 0.0652610900020274 FLNA/ITGB1 2 GO:0072378 blood coagulation, fibrin clot formation 2/320 10/18722 0.0119700486165709 0.0652610900020274 FN1/FBLN1 2 GO:0098903 regulation of membrane repolarization during action potential 2/320 10/18722 0.0119700486165709 0.0652610900020274 FLNA/CAV1 2 GO:1902946 protein localization to early endosome 2/320 10/18722 0.0119700486165709 0.0652610900020274 MSN/EZR 2 GO:0071229 cellular response to acid chemical 5/320 80/18722 0.0119729050485248 0.0652610900020274 CYBB/CYBA/KLF2/PLEC/CEBPB 5 GO:0120193 tight junction organization 5/320 80/18722 0.0119729050485248 0.0652610900020274 ACTG1/MTDH/TGFBR1/PLEC/GJA1 5 GO:0106106 cold-induced thermogenesis 7/320 144/18722 0.0120034918687175 0.0652610900020274 PLAC8/CXCR4/CAV1/ARRDC3/ID1/GJA1/CEBPB 7 GO:0120161 regulation of cold-induced thermogenesis 7/320 144/18722 0.0120034918687175 0.0652610900020274 PLAC8/CXCR4/CAV1/ARRDC3/ID1/GJA1/CEBPB 7 GO:0009612 response to mechanical stimulus 9/320 216/18722 0.0122420703971909 0.0664707422880326 TXNIP/CXCR4/CYBA/JUN/PLEC/STAT1/RHOA/CTNNB1/GJA1 9 GO:0010721 negative regulation of cell development 8/320 180/18722 0.0124188739262511 0.0672468908650458 TSPO/FBLN1/FBN1/SEMA6D/B2M/GBP1/ID1/CTNNB1 8 GO:0043409 negative regulation of MAPK cascade 8/320 180/18722 0.0124188739262511 0.0672468908650458 PTPRC/CAV1/EZR/FBLN1/TIMP3/GBP1/PBK/PDCD4 8 GO:0043524 negative regulation of neuron apoptotic process 7/320 145/18722 0.012433839453266 0.0672468908650458 CORO1A/SOD2/ISL1/HMOX1/PPT1/RHOA/CEBPB 7 GO:0007346 regulation of mitotic cell cycle 15/320 457/18722 0.0124587438925794 0.0672935029596575 AIF1/IGF2/NEK6/TIMP2/ANXA1/CDC42/BTG3/ZFP36L2/MKI67/PPP1R10/CDK1/EZH2/CTNNB1/SOX4/CKS2 15 GO:0009141 nucleoside triphosphate metabolic process 6/320 112/18722 0.0125581911663267 0.0675454918816032 TMSB4X/ALDOA/SAMHD1/ENO1/PARP1/RHOA 6 GO:0046632 alpha-beta T cell differentiation 6/320 112/18722 0.0125581911663267 0.0675454918816032 HLA-DRB1/HLA-DRA/ANXA1/HMGB1/CTSL/RHOA 6 GO:1901222 regulation of NIK/NF-kappaB signaling 6/320 112/18722 0.0125581911663267 0.0675454918816032 TMSB4X/LAPTM5/LITAF/HMGB1/RHOA/PDCD4 6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 5/320 81/18722 0.0125871318366008 0.0675454918816032 PEG10/CAV1/HTRA1/FBN1/HSPA1A 5 GO:0046209 nitric oxide metabolic process 5/320 81/18722 0.0125871318366008 0.0675454918816032 AIF1/TSPO/CAV1/KLF2/DYNLL1 5 GO:0072521 purine-containing compound metabolic process 14/320 416/18722 0.0127018228623544 0.067910549217018 GAPDH/CROT/TMSB4X/LDHA/ALDOA/PKM/TPI1/SAMHD1/ENO1/PDE4B/PARP1/PGK1/PPT1/RHOA 14 GO:0007566 embryo implantation 4/320 53/18722 0.012713878926431 0.067910549217018 ARHGDIB/FBLN1/STC2/GJA1 4 GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 4/320 53/18722 0.012713878926431 0.067910549217018 PLEK/ARRDC3/STMN1/PDE4B 4 GO:0042113 B cell activation 12/320 334/18722 0.0127209015232265 0.067910549217018 PTPRC/MNDA/TNFSF13B/TYROBP/BST2/LAPTM5/ITGB1/ZFP36L2/CD74/SLC39A10/EZH2/TFRC 12 GO:0007043 cell-cell junction assembly 7/320 146/18722 0.0128751993700533 0.0686455790929808 CAV1/ACTG1/MTDH/RHOA/ACTB/CTNNB1/GJA1 7 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 10/320 256/18722 0.012968686886349 0.0690549152247347 PEG10/ZEB2/CAV1/HTRA1/FBN1/NREP/TGFBR1/PARP1/HSPA1A/LRP2 10 GO:0021522 spinal cord motor neuron differentiation 3/320 29/18722 0.0130116752550049 0.0691946488464351 LMO4/ISL1/SOX4 3 GO:0071347 cellular response to interleukin-1 6/320 113/18722 0.0130779127989149 0.0694575008806122 CCL3L3/CCL3/GBP2/KLF2/GBP1/CEBPB 6 GO:0060401 cytosolic calcium ion transport 8/320 182/18722 0.0132037270320942 0.0698653987586869 PTPRC/CORO1A/CAV1/CCL3/CYBA/ATP2B1/SRI/GSTO1 8 GO:0001892 embryonic placenta development 5/320 82/18722 0.0132223479741755 0.0698653987586869 KRT19/IGF2/KRT8/PHLDA2/CEBPB 5 GO:0009205 purine ribonucleoside triphosphate metabolic process 5/320 82/18722 0.0132223479741755 0.0698653987586869 TMSB4X/ALDOA/ENO1/PARP1/RHOA 5 GO:2001057 reactive nitrogen species metabolic process 5/320 82/18722 0.0132223479741755 0.0698653987586869 AIF1/TSPO/CAV1/KLF2/DYNLL1 5 GO:0034764 positive regulation of transmembrane transport 9/320 219/18722 0.0132978270291885 0.0701744843992425 TMSB4X/CTSS/FLNA/SRI/ITGB1/IFNGR2/TCAF1/GSTO1/AZIN1 9 GO:0030520 intracellular estrogen receptor signaling pathway 4/320 54/18722 0.013550725110896 0.071233457029516 LBH/ISL1/PARP1/UBA5 4 GO:0030834 regulation of actin filament depolymerization 4/320 54/18722 0.013550725110896 0.071233457029516 PLEK/CAPG/CAPZA1/CAPZB 4 GO:0086002 cardiac muscle cell action potential involved in contraction 4/320 54/18722 0.013550725110896 0.071233457029516 FLNA/CAV1/DSP/GJA1 4 GO:0032386 regulation of intracellular transport 12/320 337/18722 0.0135674566026692 0.071233457029516 ITGB2/FLNA/LCP1/MSN/EZR/BNIP3L/OAZ1/CDC42/ICE1/TCAF1/CDK1/UBE2J1 12 GO:0051261 protein depolymerization 6/320 114/18722 0.0136125200684493 0.0713793565010567 PLEK/CCSAP/CAPG/STMN1/CAPZA1/CAPZB 6 GO:0034329 cell junction assembly 14/320 420/18722 0.0137047355081133 0.0716720581681974 FN1/CAV1/ACTG1/RAB17/MTDH/CDC42/PLEC/CAPZA1/DST/PTPRA/RHOA/ACTB/CTNNB1/GJA1 14 GO:2001056 positive regulation of cysteine-type endopeptidase activity 7/320 148/18722 0.0137915455041734 0.0716720581681974 TNFSF10/LAPTM5/PMAIP1/HMGB1/S100A9/RHOA/PDCD6 7 GO:0001655 urogenital system development 12/320 338/18722 0.0138590002975854 0.0716720581681974 ANXA1/FBN1/TGFBR1/PSAP/ADAMTS6/STAT1/MAGED1/LRP2/RHOA/CTNNB1/SOX4/LGR5 12 GO:0051346 negative regulation of hydrolase activity 13/320 379/18722 0.0138767211380657 0.0716720581681974 GAPDH/SERPINB9/SERPINA1/BST2/PLAUR/GPX1/TIMP2/SERPINB1/ANXA1/TIMP3/TFPI2/DHCR24/CARD16 13 GO:0043367 CD4-positive, alpha-beta T cell differentiation 5/320 83/18722 0.0138788541981263 0.0716720581681974 HLA-DRB1/HLA-DRA/ANXA1/HMGB1/CTSL 5 GO:0050672 negative regulation of lymphocyte proliferation 5/320 83/18722 0.0138788541981263 0.0716720581681974 MNDA/LST1/TYROBP/HLA-DRB1/CEBPB 5 GO:0055001 muscle cell development 8/320 184/18722 0.0140242922584107 0.0716720581681974 KRT19/KRT8/GPX1/ACTG1/ISL1/ITGB1/PLEC/CDK1 8 GO:2001257 regulation of cation channel activity 8/320 184/18722 0.0140242922584107 0.0716720581681974 TMSB4X/CTSS/CAV1/SRI/ITGB1/IFNGR2/PDE4B/GSTO1 8 GO:0046916 cellular transition metal ion homeostasis 6/320 115/18722 0.0141622155798652 0.0716720581681974 FTH1/SRI/HMOX1/SLC39A10/S100A9/TFRC 6 GO:0051209 release of sequestered calcium ion into cytosol 6/320 115/18722 0.0141622155798652 0.0716720581681974 PTPRC/CORO1A/CCL3/CYBA/SRI/GSTO1 6 GO:0017145 stem cell division 3/320 30/18722 0.0142778410771867 0.0716720581681974 EVI2B/LBH/ZFP36L2 3 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway 3/320 30/18722 0.0142778410771867 0.0716720581681974 LAPTM5/EZR/GBP1 3 GO:0070229 negative regulation of lymphocyte apoptotic process 3/320 30/18722 0.0142778410771867 0.0716720581681974 TSC22D3/CD74/SLC39A10 3 GO:1903579 negative regulation of ATP metabolic process 3/320 30/18722 0.0142778410771867 0.0716720581681974 TSPO/PARP1/RHOA 3 GO:0000768 syncytium formation by plasma membrane fusion 4/320 55/18722 0.0144217986724213 0.0716720581681974 CD53/TYROBP/ADAM12/MYH9 4 GO:0003229 ventricular cardiac muscle tissue development 4/320 55/18722 0.0144217986724213 0.0716720581681974 DSP/ISL1/TGFBR1/LRP2 4 GO:0045620 negative regulation of lymphocyte differentiation 4/320 55/18722 0.0144217986724213 0.0716720581681974 FGL2/ANXA1/HMGB1/CD74 4 GO:0140253 cell-cell fusion 4/320 55/18722 0.0144217986724213 0.0716720581681974 CD53/TYROBP/ADAM12/MYH9 4 GO:0043433 negative regulation of DNA-binding transcription factor activity 8/320 185/18722 0.0144482411150334 0.0716720581681974 TMSB4X/FLNA/ANXA4/BHLHE40/SRI/HMOX1/ID1/EZH2 8 GO:0051896 regulation of protein kinase B signaling 8/320 185/18722 0.0144482411150334 0.0716720581681974 IGF2/CCL3/GPX1/MTDH/ITGB1/TGFBR1/LRP2/PDCD6 8 GO:0003093 regulation of glomerular filtration 2/320 11/18722 0.0144662382653138 0.0716720581681974 CYBA/GJA1 2 GO:0003139 secondary heart field specification 2/320 11/18722 0.0144662382653138 0.0716720581681974 ISL1/LRP2 2 GO:0003263 cardioblast proliferation 2/320 11/18722 0.0144662382653138 0.0716720581681974 ISL1/CTNNB1 2 GO:0003264 regulation of cardioblast proliferation 2/320 11/18722 0.0144662382653138 0.0716720581681974 ISL1/CTNNB1 2 GO:0010269 response to selenium ion 2/320 11/18722 0.0144662382653138 0.0716720581681974 GPX1/SOD2 2 GO:0019372 lipoxygenase pathway 2/320 11/18722 0.0144662382653138 0.0716720581681974 GPX1/GPX4 2 GO:0033483 gas homeostasis 2/320 11/18722 0.0144662382653138 0.0716720581681974 CAV1/SOD2 2 GO:0042167 heme catabolic process 2/320 11/18722 0.0144662382653138 0.0716720581681974 BLVRA/HMOX1 2 GO:0043312 neutrophil degranulation 2/320 11/18722 0.0144662382653138 0.0716720581681974 ITGB2/STXBP2 2 GO:0045060 negative thymic T cell selection 2/320 11/18722 0.0144662382653138 0.0716720581681974 PTPRC/CD74 2 GO:0046149 pigment catabolic process 2/320 11/18722 0.0144662382653138 0.0716720581681974 BLVRA/HMOX1 2 GO:0046598 positive regulation of viral entry into host cell 2/320 11/18722 0.0144662382653138 0.0716720581681974 HLA-DRB1/CD74 2 GO:0046643 regulation of gamma-delta T cell activation 2/320 11/18722 0.0144662382653138 0.0716720581681974 PTPRC/SOX4 2 GO:0048103 somatic stem cell division 2/320 11/18722 0.0144662382653138 0.0716720581681974 LBH/ZFP36L2 2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 2/320 11/18722 0.0144662382653138 0.0716720581681974 SRI/GSTO1 2 GO:0060742 epithelial cell differentiation involved in prostate gland development 2/320 11/18722 0.0144662382653138 0.0716720581681974 PSAP/CTNNB1 2 GO:0072497 mesenchymal stem cell differentiation 2/320 11/18722 0.0144662382653138 0.0716720581681974 KRT18/CTNNB1 2 GO:0075294 positive regulation by symbiont of entry into host 2/320 11/18722 0.0144662382653138 0.0716720581681974 HLA-DRB1/CD74 2 GO:0106049 regulation of cellular response to osmotic stress 2/320 11/18722 0.0144662382653138 0.0716720581681974 EFHD1/YBX3 2 GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 2/320 11/18722 0.0144662382653138 0.0716720581681974 ARRDC3/PDE4B 2 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction 2/320 11/18722 0.0144662382653138 0.0716720581681974 CAV1/SRI 2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway 2/320 11/18722 0.0144662382653138 0.0716720581681974 LAPTM5/HSPA1A 2 GO:1903961 positive regulation of anion transmembrane transport 2/320 11/18722 0.0144662382653138 0.0716720581681974 ITGB1/TCAF1 2 GO:1904181 positive regulation of membrane depolarization 2/320 11/18722 0.0144662382653138 0.0716720581681974 TSPO/PARP1 2 GO:1905668 positive regulation of protein localization to endosome 2/320 11/18722 0.0144662382653138 0.0716720581681974 MSN/EZR 2 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 2/320 11/18722 0.0144662382653138 0.0716720581681974 HMGB1/CD74 2 GO:0006112 energy reserve metabolic process 5/320 84/18722 0.0145569444851705 0.0719489170008666 IGF2/PYGL/PHLDA2/HMGB1/UGP2 5 GO:0032945 negative regulation of mononuclear cell proliferation 5/320 84/18722 0.0145569444851705 0.0719489170008666 MNDA/LST1/TYROBP/HLA-DRB1/CEBPB 5 GO:0050920 regulation of chemotaxis 9/320 223/18722 0.0148088231353944 0.0731064004724608 TMSB4X/AIF1/CXCR4/CCL3/PGF/HMGB1/CD74/SEMA6D/HSPB1 9 GO:0042886 amide transport 11/320 301/18722 0.0148713683103511 0.0732897909525637 HLA-DRB1/ANXA1/DYNLL1/ISL1/SRI/HMGN3/CD74/PSAP/LRP2/SOX4/GJA1 11 GO:0120032 regulation of plasma membrane bounded cell projection assembly 8/320 186/18722 0.0148814459363991 0.0732897909525637 EPS8L1/CAV1/RAB17/CDC42/PFN1/TGFBR1/CAPZB/ACTR3 8 GO:0061564 axon development 15/320 467/18722 0.0148999687266979 0.0732936556889471 TSPO/FLNA/FN1/NRP2/EFNB1/S100A6/C12orf57/ISL1/NREP/ITGB1/STMN1/SEMA6D/EMB/VASP/ACTB 15 GO:0031330 negative regulation of cellular catabolic process 10/320 262/18722 0.0150314090192527 0.0738522973454843 TSPO/RPL23/TIMP2/ZFP36/FUS/TIMP3/NAMPT/HMOX1/PBK/YBX3 10 GO:0001933 negative regulation of protein phosphorylation 12/320 342/18722 0.0150732354453244 0.0739698442518769 PTPRC/MYADM/CAV1/FBLN1/PARP14/MLLT1/IGFBP3/PLEC/PLPP3/PBK/HSPB1/PDCD4 12 GO:0071333 cellular response to glucose stimulus 7/320 151/18722 0.0152523112142936 0.0746855588801357 HLA-DRB1/CYBA/DYNLL1/SRI/HMGN3/TRA2B/SOX4 7 GO:0055072 iron ion homeostasis 5/320 85/18722 0.0152569058944411 0.0746855588801357 FTH1/SRI/B2M/HMOX1/TFRC 5 GO:0014902 myotube differentiation 6/320 117/18722 0.0153076683896449 0.0746855588801357 CD53/GPX1/ADAM12/MYH9/PLEC/BHLHE41 6 GO:0051225 spindle assembly 6/320 117/18722 0.0153076683896449 0.0746855588801357 FLNA/NEK6/CCSAP/TUBB/HSPA1A/RHOA 6 GO:0010332 response to gamma radiation 4/320 56/18722 0.0153275299928255 0.0746855588801357 PTPRC/CYBA/GPX1/PARP1 4 GO:0051653 spindle localization 4/320 56/18722 0.0153275299928255 0.0746855588801357 ITGB1/MYH9/ACTR3/GJA1 4 GO:0010001 glial cell differentiation 9/320 225/18722 0.0156101376145951 0.075534510505882 VIM/TNFRSF1B/CXCR4/PLEC/CDK1/S100A9/RHOA/CTNNB1/SOX4 9 GO:0016485 protein processing 9/320 225/18722 0.0156101376145951 0.075534510505882 CTSS/SRGN/ENO1/MYH9/PARP1/DHCR24/PGK1/CTSL/CARD16 9 GO:0042326 negative regulation of phosphorylation 13/320 385/18722 0.0156108150658834 0.075534510505882 PTPRC/MYADM/CAV1/FBLN1/DYNLL1/PARP14/MLLT1/IGFBP3/PLEC/PLPP3/PBK/HSPB1/PDCD4 13 GO:0071711 basement membrane organization 3/320 31/18722 0.0156114404578953 0.075534510505882 CTSS/CAV1/ITGB1 3 GO:0090162 establishment of epithelial cell polarity 3/320 31/18722 0.0156114404578953 0.075534510505882 MSN/CDC42/RHOA 3 GO:1900027 regulation of ruffle assembly 3/320 31/18722 0.0156114404578953 0.075534510505882 EPS8L1/CAV1/PFN1 3 GO:0051051 negative regulation of transport 15/320 470/18722 0.0157001967353252 0.0758330792659554 TNFRSF1B/CORO1A/BST2/CAV1/C4orf3/ANXA1/OAZ1/HMGB1/SRI/CD74/SLC43A2/HMOX1/UBE2J1/GSTO1/GJA1 15 GO:0030336 negative regulation of cell migration 12/320 344/18722 0.0157098537879133 0.0758330792659554 AIF1/BST2/ARHGDIB/HMGB1/IGFBP3/CD74/CLIC4/SEMA6D/TCAF1/HMOX1/RHOA/GJA1 12 GO:0098754 detoxification 7/320 152/18722 0.0157628053224665 0.0758866824900018 GPX3/GPX1/SOD2/GSTO1/GPX4/S100A9/SOD3 7 GO:0006575 cellular modified amino acid metabolic process 8/320 188/18722 0.0157760552417501 0.0758866824900018 CROT/CLIC3/SLC6A8/GPX1/CTSB/GSTO1/GPX4/IDH1 8 GO:0060491 regulation of cell projection assembly 8/320 188/18722 0.0157760552417501 0.0758866824900018 EPS8L1/CAV1/RAB17/CDC42/PFN1/TGFBR1/CAPZB/ACTR3 8 GO:0090287 regulation of cellular response to growth factor stimulus 11/320 304/18722 0.0158950288978276 0.0763700690765391 PEG10/ZEB2/CAV1/HTRA1/FBN1/CD63/NREP/HSPA1A/LRP2/CTNNB1/PDCD6 11 GO:2000117 negative regulation of cysteine-type endopeptidase activity 5/320 86/18722 0.0159790184184828 0.0766844414694202 SERPINB9/PLAUR/GPX1/DHCR24/CARD16 5 GO:0071241 cellular response to inorganic substance 9/320 226/18722 0.0160225450549686 0.07680412548391 CYBB/NCF1/TSPO/FUS/JUN/CLIC4/B2M/PARP1/HMOX1 9 GO:0006754 ATP biosynthetic process 4/320 57/18722 0.0162683279170581 0.0777031693355614 TMSB4X/ALDOA/ENO1/PARP1 4 GO:0006949 syncytium formation 4/320 57/18722 0.0162683279170581 0.0777031693355614 CD53/TYROBP/ADAM12/MYH9 4 GO:0033619 membrane protein proteolysis 4/320 57/18722 0.0162683279170581 0.0777031693355614 TNFRSF1B/TIMP2/TIMP3/MYH9 4 GO:0071331 cellular response to hexose stimulus 7/320 153/18722 0.0162853205819449 0.0777031693355614 HLA-DRB1/CYBA/DYNLL1/SRI/HMGN3/TRA2B/SOX4 7 GO:1903578 regulation of ATP metabolic process 5/320 87/18722 0.0167235548425788 0.0796042131056969 TMSB4X/TSPO/ENO1/PARP1/RHOA 5 GO:0030856 regulation of epithelial cell differentiation 7/320 154/18722 0.0168199959597457 0.0796042131056969 CAV1/ZFP36/STAT1/ID1/EZH2/CTNNB1/CEBPB 7 GO:0071326 cellular response to monosaccharide stimulus 7/320 154/18722 0.0168199959597457 0.0796042131056969 HLA-DRB1/CYBA/DYNLL1/SRI/HMGN3/TRA2B/SOX4 7 GO:0010644 cell communication by electrical coupling 3/320 32/18722 0.0170128344639636 0.0796042131056969 CAV1/SRI/GJA1 3 GO:0035767 endothelial cell chemotaxis 3/320 32/18722 0.0170128344639636 0.0796042131056969 TMSB4X/HMGB1/HSPB1 3 GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 3/320 32/18722 0.0170128344639636 0.0796042131056969 HLA-DRB1/HLA-DRA/ANXA1 3 GO:0060914 heart formation 3/320 32/18722 0.0170128344639636 0.0796042131056969 ISL1/LRP2/CTNNB1 3 GO:0072337 modified amino acid transport 3/320 32/18722 0.0170128344639636 0.0796042131056969 SLC6A8/LRP2/GJA1 3 GO:0002903 negative regulation of B cell apoptotic process 2/320 12/18722 0.017165380899607 0.0796042131056969 CD74/SLC39A10 2 GO:0006787 porphyrin-containing compound catabolic process 2/320 12/18722 0.017165380899607 0.0796042131056969 BLVRA/HMOX1 2 GO:0031953 negative regulation of protein autophosphorylation 2/320 12/18722 0.017165380899607 0.0796042131056969 PTPRC/CAV1 2 GO:0033015 tetrapyrrole catabolic process 2/320 12/18722 0.017165380899607 0.0796042131056969 BLVRA/HMOX1 2 GO:0034333 adherens junction assembly 2/320 12/18722 0.017165380899607 0.0796042131056969 ACTB/CTNNB1 2 GO:0043383 negative T cell selection 2/320 12/18722 0.017165380899607 0.0796042131056969 PTPRC/CD74 2 GO:0060907 positive regulation of macrophage cytokine production 2/320 12/18722 0.017165380899607 0.0796042131056969 LAPTM5/CD74 2 GO:0071635 negative regulation of transforming growth factor beta production 2/320 12/18722 0.017165380899607 0.0796042131056969 TYROBP/FN1 2 GO:0072182 regulation of nephron tubule epithelial cell differentiation 2/320 12/18722 0.017165380899607 0.0796042131056969 STAT1/CTNNB1 2 GO:0072376 protein activation cascade 2/320 12/18722 0.017165380899607 0.0796042131056969 FN1/FBLN1 2 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress 2/320 12/18722 0.017165380899607 0.0796042131056969 JUN/HSPA1A 2 GO:0098911 regulation of ventricular cardiac muscle cell action potential 2/320 12/18722 0.017165380899607 0.0796042131056969 CAV1/DSP 2 GO:0098974 postsynaptic actin cytoskeleton organization 2/320 12/18722 0.017165380899607 0.0796042131056969 ACTG1/ACTB 2 GO:1904667 negative regulation of ubiquitin protein ligase activity 2/320 12/18722 0.017165380899607 0.0796042131056969 RPL23/RPL37 2 GO:1905666 regulation of protein localization to endosome 2/320 12/18722 0.017165380899607 0.0796042131056969 MSN/EZR 2 GO:2000035 regulation of stem cell division 2/320 12/18722 0.017165380899607 0.0796042131056969 EVI2B/LBH 2 GO:2001204 regulation of osteoclast development 2/320 12/18722 0.017165380899607 0.0796042131056969 TYROBP/FBN1 2 GO:0032481 positive regulation of type I interferon production 4/320 58/18722 0.0172445797285982 0.0797923890689447 GAPDH/ISG15/HMGB1/STAT1 4 GO:0042743 hydrogen peroxide metabolic process 4/320 58/18722 0.0172445797285982 0.0797923890689447 GPX3/CYBA/GPX1/SOD2 4 GO:0070372 regulation of ERK1 and ERK2 cascade 11/320 309/18722 0.0177175112067445 0.0817586367085312 PTPRC/CCL3L3/FN1/HLA-DRB1/CCL3/EZR/FBLN1/HMGB1/TIMP3/CD74/GBP1 11 GO:0001704 formation of primary germ layer 6/320 121/18722 0.0177882416265657 0.0817586367085312 ITGB2/FN1/WLS/ITGB1/CTNNB1/GJA1 6 GO:0001838 embryonic epithelial tube formation 6/320 121/18722 0.0177882416265657 0.0817586367085312 LMO4/PFN1/VASP/LRP2/CTNNB1/SOX4 6 GO:0003206 cardiac chamber morphogenesis 6/320 121/18722 0.0177882416265657 0.0817586367085312 NRP2/DSP/ISL1/TGFBR1/LRP2/SOX4 6 GO:0042177 negative regulation of protein catabolic process 6/320 121/18722 0.0177882416265657 0.0817586367085312 FLNA/RPL23/TIMP2/TIMP3/PBK/AZIN1 6 GO:0043500 muscle adaptation 6/320 121/18722 0.0177882416265657 0.0817586367085312 TNFRSF1B/AIF1/CYBA/PARP1/HMOX1/EZH2 6 GO:0030042 actin filament depolymerization 4/320 59/18722 0.0182566511522548 0.0836510528535675 PLEK/CAPG/CAPZA1/CAPZB 4 GO:0048010 vascular endothelial growth factor receptor signaling pathway 4/320 59/18722 0.0182566511522548 0.0836510528535675 PGF/FLT1/HSPB1/PDCD6 4 GO:0009199 ribonucleoside triphosphate metabolic process 5/320 89/18722 0.0182809537092864 0.0836510528535675 TMSB4X/ALDOA/ENO1/PARP1/RHOA 5 GO:0051781 positive regulation of cell division 5/320 89/18722 0.0182809537092864 0.0836510528535675 IGF2/LBH/PGF/CDC42/RHOA 5 GO:0019730 antimicrobial humoral response 6/320 122/18722 0.0184489933094754 0.0839947076654612 GAPDH/HLA-A/LYZ/HLA-E/HMGN2/S100A9 6 GO:0051928 positive regulation of calcium ion transport 6/320 122/18722 0.0184489933094754 0.0839947076654612 TSPO/CAV1/CCL3/ATP2B1/SRI/GSTO1 6 GO:0036336 dendritic cell migration 3/320 33/18722 0.0184823011776284 0.0839947076654612 CXCR4/CDC42/HMGB1 3 GO:0045648 positive regulation of erythrocyte differentiation 3/320 33/18722 0.0184823011776284 0.0839947076654612 ISG15/STAT1/HSPA1A 3 GO:1903146 regulation of autophagy of mitochondrion 3/320 33/18722 0.0184823011776284 0.0839947076654612 TSPO/BNIP3L/VPS13C 3 GO:1990845 adaptive thermogenesis 7/320 157/18722 0.0184983504297119 0.0839947076654612 PLAC8/CXCR4/CAV1/ARRDC3/ID1/GJA1/CEBPB 7 GO:2000377 regulation of reactive oxygen species metabolic process 7/320 157/18722 0.0184983504297119 0.0839947076654612 ITGB2/TSPO/TYROBP/PAGE4/CYBA/SOD2/RHOA 7 GO:0010594 regulation of endothelial cell migration 9/320 232/18722 0.0186667468461441 0.0846662985381639 TMSB4X/NRP2/ANXA1/HMGB1/HMOX1/PLPP3/RHOA/HSPB1/PDCD6 9 GO:0032392 DNA geometric change 5/320 90/18722 0.0190943245348218 0.0863232017199584 ANXA1/HMGB3/HMGB1/RFC3/TOP2A 5 GO:0070664 negative regulation of leukocyte proliferation 5/320 90/18722 0.0190943245348218 0.0863232017199584 MNDA/LST1/TYROBP/HLA-DRB1/CEBPB 5 GO:0003231 cardiac ventricle development 6/320 123/18722 0.0191263509252228 0.0863232017199584 LMO4/DSP/ISL1/TGFBR1/LRP2/SOX4 6 GO:0010811 positive regulation of cell-substrate adhesion 6/320 123/18722 0.0191263509252228 0.0863232017199584 FLNA/MYADM/PLEKHA2/FN1/CCDC80/CDC42 6 GO:0007160 cell-matrix adhesion 9/320 233/18722 0.0191365084161379 0.0863232017199584 ITGB2/PLEKHA2/FN1/ACTG1/CD63/ITGB1/PTPRA/RHOA/CTNNB1 9 GO:0030073 insulin secretion 8/320 195/18722 0.0192144178057981 0.086580124725799 HLA-DRB1/ANXA1/DYNLL1/ISL1/SRI/HMGN3/SOX4/GJA1 8 GO:0031102 neuron projection regeneration 4/320 60/18722 0.0193048863829441 0.0867041201460053 TSPO/FLNA/ISL1/NREP 4 GO:0031638 zymogen activation 4/320 60/18722 0.0193048863829441 0.0867041201460053 ENO1/DHCR24/PGK1/CTSL 4 GO:0055008 cardiac muscle tissue morphogenesis 4/320 60/18722 0.0193048863829441 0.0867041201460053 DSP/ISL1/TGFBR1/LRP2 4 GO:0006006 glucose metabolic process 8/320 196/18722 0.0197460112243517 0.087804362369173 GAPDH/IGF2/TPI1/ENO1/PMAIP1/PHLDA2/HMGB1/PGK1 8 GO:0010922 positive regulation of phosphatase activity 3/320 34/18722 0.020020039266264 0.087804362369173 PTPRC/PLEK/SLC39A10 3 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 3/320 34/18722 0.020020039266264 0.087804362369173 CCL3/SRI/GSTO1 3 GO:0032743 positive regulation of interleukin-2 production 3/320 34/18722 0.020020039266264 0.087804362369173 PTPRC/ANXA1/PDE4B 3 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 3/320 34/18722 0.020020039266264 0.087804362369173 PMAIP1/PTTG1IP/CD74 3 GO:0050869 negative regulation of B cell activation 3/320 34/18722 0.020020039266264 0.087804362369173 MNDA/TYROBP/LAPTM5 3 GO:0001778 plasma membrane repair 2/320 13/18722 0.0200598543263551 0.087804362369173 MYH9/ANXA6 2 GO:0003334 keratinocyte development 2/320 13/18722 0.0200598543263551 0.087804362369173 FLNB/PLEC 2 GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis 2/320 13/18722 0.0200598543263551 0.087804362369173 STAT1/CTNNB1 2 GO:0010917 negative regulation of mitochondrial membrane potential 2/320 13/18722 0.0200598543263551 0.087804362369173 BNIP3L/PMAIP1 2 GO:0010958 regulation of amino acid import across plasma membrane 2/320 13/18722 0.0200598543263551 0.087804362369173 ITGB1/SLC43A2 2 GO:0031392 regulation of prostaglandin biosynthetic process 2/320 13/18722 0.0200598543263551 0.087804362369173 ANXA1/CD74 2 GO:0032429 regulation of phospholipase A2 activity 2/320 13/18722 0.0200598543263551 0.087804362369173 ANXA1/PPT1 2 GO:0034135 regulation of toll-like receptor 2 signaling pathway 2/320 13/18722 0.0200598543263551 0.087804362369173 CYBA/HMGB1 2 GO:0042492 gamma-delta T cell differentiation 2/320 13/18722 0.0200598543263551 0.087804362369173 PTPRC/SOX4 2 GO:0042769 DNA damage response, detection of DNA damage 2/320 13/18722 0.0200598543263551 0.087804362369173 PARP1/SOX4 2 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 2/320 13/18722 0.0200598543263551 0.087804362369173 SRI/GSTO1 2 GO:0070486 leukocyte aggregation 2/320 13/18722 0.0200598543263551 0.087804362369173 MSN/S100A9 2 GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 2/320 13/18722 0.0200598543263551 0.087804362369173 ARRDC3/PDE4B 2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 2/320 13/18722 0.0200598543263551 0.087804362369173 PMAIP1/TIMP3 2 GO:1903651 positive regulation of cytoplasmic transport 2/320 13/18722 0.0200598543263551 0.087804362369173 MSN/EZR 2 GO:1903789 regulation of amino acid transmembrane transport 2/320 13/18722 0.0200598543263551 0.087804362369173 ITGB1/SLC43A2 2 GO:1905244 regulation of modification of synaptic structure 2/320 13/18722 0.0200598543263551 0.087804362369173 CDC42/RHOA 2 GO:1990403 embryonic brain development 2/320 13/18722 0.0200598543263551 0.087804362369173 TRA2B/CTNNB1 2 GO:0060402 calcium ion transport into cytosol 7/320 160/18722 0.0202910038509476 0.0886283593151328 PTPRC/CORO1A/CAV1/CCL3/CYBA/SRI/GSTO1 7 GO:0090316 positive regulation of intracellular protein transport 7/320 160/18722 0.0202910038509476 0.0886283593151328 ITGB2/FLNA/OAZ1/CDC42/ICE1/TCAF1/CDK1 7 GO:2000401 regulation of lymphocyte migration 4/320 61/18722 0.0203896081390725 0.0889650061569669 AIF1/MSN/CCL3/RHOA 4 GO:0072503 cellular divalent inorganic cation homeostasis 15/320 486/18722 0.0205421732823538 0.0895361392433395 PTPRC/CORO1A/CXCR4/CAV1/CCL3/CYBA/STC2/ATP2B1/HMGB1/SRI/ANXA6/SLC39A10/GSTO1/S100A9/GJA1 15 GO:0048738 cardiac muscle tissue development 9/320 236/18722 0.0205972323970305 0.0895871202784528 DSP/ISL1/CDC42/ITGB1/TGFBR1/PLEC/CDK1/LRP2/GJA1 9 GO:0090068 positive regulation of cell cycle process 9/320 236/18722 0.0205972323970305 0.0895871202784528 AIF1/IGF2/ANXA1/CDC42/PPP1R10/CDK1/RHOA/EZH2/DBF4 9 GO:0007548 sex differentiation 10/320 276/18722 0.0207852843351359 0.0902151206646863 TNFSF10/FLNA/CYP19A1/TGFBR1/DHCR24/LRP2/IDH1/YBX3/CTNNB1/CEBPB 10 GO:1903829 positive regulation of cellular protein localization 10/320 276/18722 0.0207852843351359 0.0902151206646863 ITGB2/FLNA/TYROBP/MSN/EZR/ITGB1/TCAF1/PARP1/CDK1/TFRC 10 GO:0019318 hexose metabolic process 9/320 237/18722 0.0211015518990165 0.0914917234488312 GAPDH/ALDOA/IGF2/TPI1/ENO1/PMAIP1/PHLDA2/HMGB1/PGK1 9 GO:0009306 protein secretion 12/320 359/18722 0.0211534702249451 0.0916206907436825 PLEK/HLA-DRB1/EZR/ANXA1/WLS/DYNLL1/ISL1/SRI/HMGN3/MYH10/SOX4/GJA1 12 GO:0015980 energy derivation by oxidation of organic compounds 11/320 318/18722 0.0213843986370653 0.0920281569448393 IGF2/PYGL/PHLDA2/HMGB1/PLEC/NDUFB1/CDK1/UGP2/NDUFB7/RHOA/IDH1 11 GO:0046700 heterocycle catabolic process 14/320 445/18722 0.0214263809199793 0.0920281569448393 VIM/TNFRSF1B/UPP1/APOBEC3A/ZFP36/FUS/SAMHD1/BLVRA/ZFP36L2/SSB/PDE4B/HMOX1/HSPA1A/YBX3 14 GO:0032613 interleukin-10 production 4/320 62/18722 0.0215111177392036 0.0920281569448393 TYROBP/HLA-DRB1/ISG15/HMGB1 4 GO:0032615 interleukin-12 production 4/320 62/18722 0.0215111177392036 0.0920281569448393 HLA-B/LAPTM5/ISL1/HMGB1 4 GO:0032653 regulation of interleukin-10 production 4/320 62/18722 0.0215111177392036 0.0920281569448393 TYROBP/HLA-DRB1/ISG15/HMGB1 4 GO:0032655 regulation of interleukin-12 production 4/320 62/18722 0.0215111177392036 0.0920281569448393 HLA-B/LAPTM5/ISL1/HMGB1 4 GO:0032757 positive regulation of interleukin-8 production 4/320 62/18722 0.0215111177392036 0.0920281569448393 FCN1/HMGB1/CD74/HSPA1A 4 GO:0070265 necrotic cell death 4/320 62/18722 0.0215111177392036 0.0920281569448393 TSPO/CAV1/PYGL/YBX3 4 GO:0035592 establishment of protein localization to extracellular region 12/320 360/18722 0.0215605923734899 0.0920281569448393 PLEK/HLA-DRB1/EZR/ANXA1/WLS/DYNLL1/ISL1/SRI/HMGN3/MYH10/SOX4/GJA1 12 GO:0001893 maternal placenta development 3/320 35/18722 0.0216261714408129 0.0920281569448393 STC2/CTSB/GJA1 3 GO:0018149 peptide cross-linking 3/320 35/18722 0.0216261714408129 0.0920281569448393 FN1/ANXA1/DSP 3 GO:0039694 viral RNA genome replication 3/320 35/18722 0.0216261714408129 0.0920281569448393 APOBEC3A/CDC42/TOP2A 3 GO:0045907 positive regulation of vasoconstriction 3/320 35/18722 0.0216261714408129 0.0920281569448393 CAV1/RHOA/GJA1 3 GO:0046640 regulation of alpha-beta T cell proliferation 3/320 35/18722 0.0216261714408129 0.0920281569448393 PTPRC/HLA-A/HLA-E 3 GO:0097421 liver regeneration 3/320 35/18722 0.0216261714408129 0.0920281569448393 HMOX1/EZH2/CEBPB 3 GO:1903514 release of sequestered calcium ion into cytosol by endoplasmic reticulum 3/320 35/18722 0.0216261714408129 0.0920281569448393 CCL3/SRI/GSTO1 3 GO:2000403 positive regulation of lymphocyte migration 3/320 35/18722 0.0216261714408129 0.0920281569448393 AIF1/CCL3/RHOA 3 GO:0097306 cellular response to alcohol 5/320 93/18722 0.0216760114714656 0.0920506468654635 CYBB/KLF2/SOD2/ATP2B1/CTNNB1 5 GO:1901796 regulation of signal transduction by p53 class mediator 5/320 93/18722 0.0216760114714656 0.0920506468654635 RPL23/RPL37/PMAIP1/PTTG1IP/CD74 5 GO:0002791 regulation of peptide secretion 8/320 200/18722 0.0219774163705938 0.0932347889561538 HLA-DRB1/DYNLL1/ISL1/SRI/HMGN3/CD74/SOX4/GJA1 8 GO:0071322 cellular response to carbohydrate stimulus 7/320 163/18722 0.0222014518407748 0.0940886143652116 HLA-DRB1/CYBA/DYNLL1/SRI/HMGN3/TRA2B/SOX4 7 GO:0051054 positive regulation of DNA metabolic process 8/320 201/18722 0.0225620141907062 0.095223719248869 PTPRC/FUS/HMGB1/PARP1/PPP1R10/RFC3/CTNNB1/TFRC 8 GO:0001738 morphogenesis of a polarized epithelium 5/320 94/18722 0.0225845219902932 0.095223719248869 MSN/ACTG1/CDC42/RHOA/ACTB 5 GO:0002690 positive regulation of leukocyte chemotaxis 5/320 94/18722 0.0225845219902932 0.095223719248869 AIF1/CCL3/PGF/HMGB1/CD74 5 GO:0051702 biological process involved in interaction with symbiont 5/320 94/18722 0.0225845219902932 0.095223719248869 GAPDH/FN1/CCL3/GPX1/JUN 5 GO:1902414 protein localization to cell junction 5/320 94/18722 0.0225845219902932 0.095223719248869 FLNA/ACTG1/DSP/ACTB/HSPB1 5 GO:0002475 antigen processing and presentation via MHC class Ib 2/320 14/18722 0.0231422362026679 0.0957825825923934 HLA-E/B2M 2 GO:0006596 polyamine biosynthetic process 2/320 14/18722 0.0231422362026679 0.0957825825923934 OAZ1/AZIN1 2 GO:0010771 negative regulation of cell morphogenesis involved in differentiation 2/320 14/18722 0.0231422362026679 0.0957825825923934 FBLN1/GBP1 2 GO:0043922 negative regulation by host of viral transcription 2/320 14/18722 0.0231422362026679 0.0957825825923934 CCL3/JUN 2 GO:0044764 multi-organism cellular process 2/320 14/18722 0.0231422362026679 0.0957825825923934 CAV1/CTSL 2 GO:0045059 positive thymic T cell selection 2/320 14/18722 0.0231422362026679 0.0957825825923934 PTPRC/CD74 2 GO:0045837 negative regulation of membrane potential 2/320 14/18722 0.0231422362026679 0.0957825825923934 BNIP3L/PMAIP1 2 GO:0046131 pyrimidine ribonucleoside metabolic process 2/320 14/18722 0.0231422362026679 0.0957825825923934 UPP1/APOBEC3A 2 GO:0046133 pyrimidine ribonucleoside catabolic process 2/320 14/18722 0.0231422362026679 0.0957825825923934 UPP1/APOBEC3A 2 GO:0047484 regulation of response to osmotic stress 2/320 14/18722 0.0231422362026679 0.0957825825923934 EFHD1/YBX3 2 GO:0071236 cellular response to antibiotic 2/320 14/18722 0.0231422362026679 0.0957825825923934 RPL23/EZH2 2 GO:0072160 nephron tubule epithelial cell differentiation 2/320 14/18722 0.0231422362026679 0.0957825825923934 STAT1/CTNNB1 2 GO:0086103 G protein-coupled receptor signaling pathway involved in heart process 2/320 14/18722 0.0231422362026679 0.0957825825923934 CAV1/PDE4B 2 GO:0099188 postsynaptic cytoskeleton organization 2/320 14/18722 0.0231422362026679 0.0957825825923934 ACTG1/ACTB 2 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading 2/320 14/18722 0.0231422362026679 0.0957825825923934 FBLN1/GBP1 2 GO:1901077 regulation of relaxation of muscle 2/320 14/18722 0.0231422362026679 0.0957825825923934 SRI/PDE4B 2 GO:1905049 negative regulation of metallopeptidase activity 2/320 14/18722 0.0231422362026679 0.0957825825923934 TIMP2/TIMP3 2 GO:2001171 positive regulation of ATP biosynthetic process 2/320 14/18722 0.0231422362026679 0.0957825825923934 TMSB4X/ENO1 2 GO:0090087 regulation of peptide transport 8/320 202/18722 0.0231575024225075 0.0957825825923934 HLA-DRB1/DYNLL1/ISL1/SRI/HMGN3/CD74/SOX4/GJA1 8 GO:0050767 regulation of neurogenesis 12/320 364/18722 0.0232474104804798 0.0958951094959387 TNFRSF1B/TSPO/CXCR4/FN1/BHLHE40/SEMA6D/B2M/BHLHE41/LRP2/ID1/EZH2/CTNNB1 12 GO:0010092 specification of animal organ identity 3/320 36/18722 0.0233007478058864 0.0958951094959387 ISL1/LRP2/CTNNB1 3 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 3/320 36/18722 0.0233007478058864 0.0958951094959387 HLA-DRB1/DYNLL1/SRI 3 GO:0070873 regulation of glycogen metabolic process 3/320 36/18722 0.0233007478058864 0.0958951094959387 IGF2/PHLDA2/HMGB1 3 GO:0090322 regulation of superoxide metabolic process 3/320 36/18722 0.0233007478058864 0.0958951094959387 ITGB2/TYROBP/CYBA 3 GO:0032479 regulation of type I interferon production 5/320 95/18722 0.0235173650189128 0.0965042789186074 GAPDH/ISG15/HMGB1/REL/STAT1 5 GO:0032606 type I interferon production 5/320 95/18722 0.0235173650189128 0.0965042789186074 GAPDH/ISG15/HMGB1/REL/STAT1 5 GO:0046661 male sex differentiation 7/320 165/18722 0.0235421861447135 0.0965042789186074 TNFSF10/FLNA/TGFBR1/DHCR24/LRP2/YBX3/CTNNB1 7 GO:0050796 regulation of insulin secretion 7/320 165/18722 0.0235421861447135 0.0965042789186074 HLA-DRB1/DYNLL1/ISL1/SRI/HMGN3/SOX4/GJA1 7 GO:0044270 cellular nitrogen compound catabolic process 14/320 451/18722 0.0236903005929538 0.0970151853816501 VIM/TNFRSF1B/UPP1/APOBEC3A/ZFP36/FUS/SAMHD1/BLVRA/ZFP36L2/SSB/PDE4B/HMOX1/HSPA1A/YBX3 14 GO:1901361 organic cyclic compound catabolic process 15/320 495/18722 0.0237228200729272 0.097052170833005 VIM/TNFRSF1B/UPP1/APOBEC3A/ZFP36/FUS/CYP19A1/SAMHD1/BLVRA/ZFP36L2/SSB/PDE4B/HMOX1/HSPA1A/YBX3 15 GO:0002790 peptide secretion 9/320 242/18722 0.0237572466919086 0.0970968776765245 HLA-DRB1/ANXA1/DYNLL1/ISL1/SRI/HMGN3/CD74/SOX4/GJA1 9 GO:0045995 regulation of embryonic development 4/320 64/18722 0.0238655993593555 0.0972511405846717 CCSAP/PHLDA2/CDK1/CTNNB1 4 GO:0048857 neural nucleus development 4/320 64/18722 0.0238655993593555 0.0972511405846717 DYNLL1/CDC42/RHOA/ACTB 4 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 4/320 64/18722 0.0238655993593555 0.0972511405846717 HLA-DRB1/DYNLL1/SRI/HMGN3 4 GO:0008544 epidermis development 11/320 324/18722 0.0241213279597467 0.0981963814085452 TXNIP/HLA-DRB1/ZFP36/ANXA1/DSP/FLNB/CLIC4/PLEC/EZH2/CTNNB1/LGR5 11 GO:0044262 cellular carbohydrate metabolic process 10/320 283/18722 0.0242001006822405 0.0984200945069071 PLEK/IGF2/TPI1/PYGL/PMAIP1/PHLDA2/HMGB1/ISYNA1/UGP2/IDH1 10 GO:0030307 positive regulation of cell growth 7/320 166/18722 0.024233044930082 0.0984571697650924 CXCR4/FN1/CYBA/CDC42/TGFBR1/S100A9/RHOA 7 GO:0010769 regulation of cell morphogenesis involved in differentiation 5/320 96/18722 0.0244747434706744 0.0992440039458555 FLNA/MYADM/FBLN1/CDC42/GBP1 5 GO:0044264 cellular polysaccharide metabolic process 5/320 96/18722 0.0244747434706744 0.0992440039458555 IGF2/PYGL/PHLDA2/HMGB1/UGP2 5 GO:0001701 in utero embryonic development 12/320 367/18722 0.024575028335453 0.0995529579236195 KRT19/IGF2/KRT8/KLF2/MBD3/PHLDA2/ITGB1/TGFBR1/MYH9/YBX3/CTNNB1/CEBPB 12 GO:0060562 epithelial tube morphogenesis 11/320 325/18722 0.0246012122673962 0.0995614192839189 CXCR4/LMO4/PFN1/CLIC4/VASP/MAGED1/LRP2/RHOA/CTNNB1/SOX4/LGR5 11 GO:0002369 T cell cytokine production 3/320 37/18722 0.0250437491044383 0.10046676825198 HLA-A/TNFRSF1B/B2M 3 GO:0002724 regulation of T cell cytokine production 3/320 37/18722 0.0250437491044383 0.10046676825198 HLA-A/TNFRSF1B/B2M 3 GO:0003161 cardiac conduction system development 3/320 37/18722 0.0250437491044383 0.10046676825198 ISL1/CDC42/GJA1 3 GO:0016202 regulation of striated muscle tissue development 3/320 37/18722 0.0250437491044383 0.10046676825198 IGF2/YBX3/CTNNB1 3 GO:0032570 response to progesterone 3/320 37/18722 0.0250437491044383 0.10046676825198 TXNIP/TSPO/CAV1 3 GO:0043029 T cell homeostasis 3/320 37/18722 0.0250437491044383 0.10046676825198 TSC22D3/CORO1A/PMAIP1 3 GO:0043368 positive T cell selection 3/320 37/18722 0.0250437491044383 0.10046676825198 PTPRC/CD74/CTSL 3 GO:0043403 skeletal muscle tissue regeneration 3/320 37/18722 0.0250437491044383 0.10046676825198 GPX1/ANXA1/EZH2 3 GO:1905332 positive regulation of morphogenesis of an epithelium 3/320 37/18722 0.0250437491044383 0.10046676825198 MAGED1/CTNNB1/GJA1 3 GO:0071677 positive regulation of mononuclear cell migration 4/320 65/18722 0.0250990680081092 0.10049355524177 AIF1/CCL3/HMGB1/RHOA 4 GO:0090307 mitotic spindle assembly 4/320 65/18722 0.0250990680081092 0.10049355524177 FLNA/CCSAP/HSPA1A/RHOA 4 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 6/320 131/18722 0.0251633534676643 0.100653413870657 PEG10/CAV1/HTRA1/FBN1/HSPA1A/LRP2 6 GO:0070167 regulation of biomineral tissue development 5/320 97/18722 0.0254568520797832 0.101630640380352 SRGN/CCL3/ISG15/ATP2B1/CEBPB 5 GO:0120162 positive regulation of cold-induced thermogenesis 5/320 97/18722 0.0254568520797832 0.101630640380352 PLAC8/CXCR4/CAV1/GJA1/CEBPB 5 GO:0002833 positive regulation of response to biotic stimulus 7/320 168/18722 0.0256563274941427 0.102328132438029 MNDA/FCN1/TYROBP/HLA-DRB1/CYBA/HLA-E/HMGB1 7 GO:0009314 response to radiation 14/320 456/18722 0.0257096881483542 0.102442074666345 PTPRC/ADIRF/CYBA/GPX1/RDH13/BHLHE40/ANXA1/SOD2/ITGB1/JUN/NAMPT/PARP1/PBK/CARD16 14 GO:0035264 multicellular organism growth 6/320 132/18722 0.0259976386756007 0.102677453736358 PLAC8/IGF2/EZR/KLF2/CLIC4/PLEC 6 GO:0072175 epithelial tube formation 6/320 132/18722 0.0259976386756007 0.102677453736358 LMO4/PFN1/VASP/LRP2/CTNNB1/SOX4 6 GO:0003007 heart morphogenesis 9/320 246/18722 0.0260472722588253 0.102677453736358 FLNA/NRP2/DSP/ISL1/TGFBR1/LRP2/CTNNB1/SOX4/PDCD4 9 GO:0014015 positive regulation of gliogenesis 4/320 66/18722 0.0263703180549145 0.102677453736358 TNFRSF1B/TSPO/CXCR4/LRP2 4 GO:0019229 regulation of vasoconstriction 4/320 66/18722 0.0263703180549145 0.102677453736358 CAV1/ATP2B1/RHOA/GJA1 4 GO:0042093 T-helper cell differentiation 4/320 66/18722 0.0263703180549145 0.102677453736358 HLA-DRB1/HLA-DRA/ANXA1/HMGB1 4 GO:0042446 hormone biosynthetic process 4/320 66/18722 0.0263703180549145 0.102677453736358 TSPO/CYP11A1/CYP19A1/STC2 4 GO:0050918 positive chemotaxis 4/320 66/18722 0.0263703180549145 0.102677453736358 CORO1A/CCL3/PGF/HMGB1 4 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway 2/320 15/18722 0.026405299465918 0.102677453736358 LBH/ISL1 2 GO:0042994 cytoplasmic sequestering of transcription factor 2/320 15/18722 0.026405299465918 0.102677453736358 TMSB4X/SRI 2 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 2/320 15/18722 0.026405299465918 0.102677453736358 PTTG1IP/CD74 2 GO:0048569 post-embryonic animal organ development 2/320 15/18722 0.026405299465918 0.102677453736358 LDHA/FBN1 2 GO:0051284 positive regulation of sequestering of calcium ion 2/320 15/18722 0.026405299465918 0.102677453736358 SRI/GSTO1 2 GO:0060413 atrial septum morphogenesis 2/320 15/18722 0.026405299465918 0.102677453736358 ISL1/SOX4 2 GO:0071474 cellular hyperosmotic response 2/320 15/18722 0.026405299465918 0.102677453736358 EFHD1/YBX3 2 GO:0098760 response to interleukin-7 2/320 15/18722 0.026405299465918 0.102677453736358 LSP1/HMGB1 2 GO:0098761 cellular response to interleukin-7 2/320 15/18722 0.026405299465918 0.102677453736358 LSP1/HMGB1 2 GO:1900029 positive regulation of ruffle assembly 2/320 15/18722 0.026405299465918 0.102677453736358 EPS8L1/PFN1 2 GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 2/320 15/18722 0.026405299465918 0.102677453736358 ZFP36/ZFP36L2 2 GO:1901841 regulation of high voltage-gated calcium channel activity 2/320 15/18722 0.026405299465918 0.102677453736358 SRI/PDE4B 2 GO:1905168 positive regulation of double-strand break repair via homologous recombination 2/320 15/18722 0.026405299465918 0.102677453736358 FUS/PARP1 2 GO:1905288 vascular associated smooth muscle cell apoptotic process 2/320 15/18722 0.026405299465918 0.102677453736358 SOD2/PDCD4 2 GO:1905459 regulation of vascular associated smooth muscle cell apoptotic process 2/320 15/18722 0.026405299465918 0.102677453736358 SOD2/PDCD4 2 GO:2001028 positive regulation of endothelial cell chemotaxis 2/320 15/18722 0.026405299465918 0.102677453736358 TMSB4X/HSPB1 2 GO:2001279 regulation of unsaturated fatty acid biosynthetic process 2/320 15/18722 0.026405299465918 0.102677453736358 ANXA1/CD74 2 GO:0001558 regulation of cell growth 13/320 414/18722 0.026414843495099 0.102677453736358 BST2/CXCR4/FN1/CYBA/ENO1/CDC42/TGFBR1/SEMA6D/S100A9/HSPA1A/PPT1/RHOA/GJA1 13 GO:0031098 stress-activated protein kinase signaling cascade 9/320 247/18722 0.0266433765774617 0.103468451144804 NCF1/PAGE4/EZR/ZFP36/CDC42/HMGB1/PBK/RHOA/PDCD4 9 GO:0032717 negative regulation of interleukin-8 production 3/320 38/18722 0.0268550898598444 0.103900029307937 TMSB4X/ANXA4/ANXA1 3 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway 3/320 38/18722 0.0268550898598444 0.103900029307937 LBH/ISL1/RHOA 3 GO:0046633 alpha-beta T cell proliferation 3/320 38/18722 0.0268550898598444 0.103900029307937 PTPRC/HLA-A/HLA-E 3 GO:0048713 regulation of oligodendrocyte differentiation 3/320 38/18722 0.0268550898598444 0.103900029307937 TNFRSF1B/CXCR4/CTNNB1 3 GO:0055074 calcium ion homeostasis 14/320 460/18722 0.0274151223742175 0.105967526333271 PTPRC/CORO1A/CXCR4/CAV1/CCL3/CYBA/STC2/ATP2B1/HMGB1/SRI/ANXA6/GSTO1/SNX10/GJA1 14 GO:0110149 regulation of biomineralization 5/320 99/18722 0.0274959974797666 0.10618080522093 SRGN/CCL3/ISG15/ATP2B1/CEBPB 5 GO:0071214 cellular response to abiotic stimulus 11/320 331/18722 0.0276275820411528 0.106392449136647 TSPO/ADIRF/CYBA/EFHD1/PLEC/NAMPT/PARP1/PBK/YBX3/CARD16/GJA1 11 GO:0104004 cellular response to environmental stimulus 11/320 331/18722 0.0276275820411528 0.106392449136647 TSPO/ADIRF/CYBA/EFHD1/PLEC/NAMPT/PARP1/PBK/YBX3/CARD16/GJA1 11 GO:0006879 cellular iron ion homeostasis 4/320 67/18722 0.0276795456974578 0.106392449136647 FTH1/SRI/HMOX1/TFRC 4 GO:1903317 regulation of protein maturation 4/320 67/18722 0.0276795456974578 0.106392449136647 ENO1/MYH9/CARD16/SOX4 4 GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 4/320 67/18722 0.0276795456974578 0.106392449136647 HLA-DRB1/HLA-DRA/ANXA1/HMGB1 4 GO:0046883 regulation of hormone secretion 9/320 249/18722 0.0278644041650906 0.107003455399772 HLA-DRB1/ANXA1/CYP19A1/DYNLL1/ISL1/SRI/HMGN3/SOX4/GJA1 9 GO:0071375 cellular response to peptide hormone stimulus 10/320 290/18722 0.0280025385864777 0.107434066331779 IGF2/PKM/CAV1/CYBA/CYP11A1/FBN1/ATP2B1/PARP1/STAT1/PTPRA 10 GO:0061640 cytoskeleton-dependent cytokinesis 5/320 100/18722 0.0285533823702349 0.109429913087363 STMN1/PLEC/MYH10/ACTR3/RHOA 5 GO:0001678 cellular glucose homeostasis 7/320 172/18722 0.0286722792055823 0.109429913087363 HLA-DRB1/CYBA/DYNLL1/SRI/HMGN3/TRA2B/SOX4 7 GO:0032506 cytokinetic process 3/320 39/18722 0.0287346214181484 0.109429913087363 MYH9/PLEC/RHOA 3 GO:0034314 Arp2/3 complex-mediated actin nucleation 3/320 39/18722 0.0287346214181484 0.109429913087363 GMFG/IQGAP2/ACTR3 3 GO:0045622 regulation of T-helper cell differentiation 3/320 39/18722 0.0287346214181484 0.109429913087363 HLA-DRB1/HLA-DRA/ANXA1 3 GO:0086091 regulation of heart rate by cardiac conduction 3/320 39/18722 0.0287346214181484 0.109429913087363 CAV1/DSP/ISL1 3 GO:1901861 regulation of muscle tissue development 3/320 39/18722 0.0287346214181484 0.109429913087363 IGF2/YBX3/CTNNB1 3 GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 3/320 39/18722 0.0287346214181484 0.109429913087363 HLA-DRB1/HLA-DRA/ANXA1 3 GO:0043491 protein kinase B signaling 8/320 211/18722 0.0290220832069614 0.109834487885246 IGF2/CCL3/GPX1/MTDH/ITGB1/TGFBR1/LRP2/PDCD6 8 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 4/320 68/18722 0.0290269266143971 0.109834487885246 HLA-DRB1/HLA-DRA/ANXA1/HMGB1 4 GO:0009206 purine ribonucleoside triphosphate biosynthetic process 4/320 68/18722 0.0290269266143971 0.109834487885246 TMSB4X/ALDOA/ENO1/PARP1 4 GO:0009988 cell-cell recognition 4/320 68/18722 0.0290269266143971 0.109834487885246 ALDOA/MSN/LY6K/SPESP1 4 GO:0031640 killing of cells of other organism 4/320 68/18722 0.0290269266143971 0.109834487885246 GAPDH/SERPINB9/LYZ/HMGN2 4 GO:0034394 protein localization to cell surface 4/320 68/18722 0.0290269266143971 0.109834487885246 FCN1/FLNA/TYROBP/CTNNB1 4 GO:0051148 negative regulation of muscle cell differentiation 4/320 68/18722 0.0290269266143971 0.109834487885246 IGF2/BHLHE41/EZH2/PDCD4 4 GO:0010632 regulation of epithelial cell migration 10/320 292/18722 0.0291630321384867 0.11019408085887 TMSB4X/NRP2/ANXA1/HMGB1/PFN1/HMOX1/PLPP3/RHOA/HSPB1/PDCD6 10 GO:0062012 regulation of small molecule metabolic process 11/320 334/18722 0.0292375633329641 0.11019408085887 TMSB4X/PLEK/IGF2/CAV1/ANXA1/ENO1/PMAIP1/PHLDA2/HMGB1/CD74/PARP1 11 GO:0000910 cytokinesis 7/320 173/18722 0.0294621822292728 0.11019408085887 CDC42/STMN1/MYH9/PLEC/MYH10/ACTR3/RHOA 7 GO:0043624 cellular protein complex disassembly 6/320 136/18722 0.0295181369371092 0.11019408085887 PLEK/CCSAP/CAPG/STMN1/CAPZA1/CAPZB 6 GO:0001977 renal system process involved in regulation of blood volume 2/320 16/18722 0.0298420078608604 0.11019408085887 CYBA/GJA1 2 GO:0003084 positive regulation of systemic arterial blood pressure 2/320 16/18722 0.0298420078608604 0.11019408085887 CYBA/RHOA 2 GO:0005980 glycogen catabolic process 2/320 16/18722 0.0298420078608604 0.11019408085887 PYGL/HMGB1 2 GO:0006266 DNA ligation 2/320 16/18722 0.0298420078608604 0.11019408085887 HMGB1/TOP2A 2 GO:0009415 response to water 2/320 16/18722 0.0298420078608604 0.11019408085887 KRT8/PLEC 2 GO:0014819 regulation of skeletal muscle contraction 2/320 16/18722 0.0298420078608604 0.11019408085887 C12orf57/GSTO1 2 GO:0017014 protein nitrosylation 2/320 16/18722 0.0298420078608604 0.11019408085887 GAPDH/S100A9 2 GO:0018119 peptidyl-cysteine S-nitrosylation 2/320 16/18722 0.0298420078608604 0.11019408085887 GAPDH/S100A9 2 GO:0021535 cell migration in hindbrain 2/320 16/18722 0.0298420078608604 0.11019408085887 FLNA/ITGB1 2 GO:0030033 microvillus assembly 2/320 16/18722 0.0298420078608604 0.11019408085887 FXYD5/EZR 2 GO:0033631 cell-cell adhesion mediated by integrin 2/320 16/18722 0.0298420078608604 0.11019408085887 ITGB1/PLPP3 2 GO:0034393 positive regulation of smooth muscle cell apoptotic process 2/320 16/18722 0.0298420078608604 0.11019408085887 SOD2/PDCD4 2 GO:0046135 pyrimidine nucleoside catabolic process 2/320 16/18722 0.0298420078608604 0.11019408085887 UPP1/APOBEC3A 2 GO:0048385 regulation of retinoic acid receptor signaling pathway 2/320 16/18722 0.0298420078608604 0.11019408085887 KLF2/EZH2 2 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 2/320 16/18722 0.0298420078608604 0.11019408085887 NAMPT/STAT1 2 GO:0061548 ganglion development 2/320 16/18722 0.0298420078608604 0.11019408085887 NRP2/CTNNB1 2 GO:0070365 hepatocyte differentiation 2/320 16/18722 0.0298420078608604 0.11019408085887 ANXA1/KRT18 2 GO:0071361 cellular response to ethanol 2/320 16/18722 0.0298420078608604 0.11019408085887 CYBB/SOD2 2 GO:0072283 metanephric renal vesicle morphogenesis 2/320 16/18722 0.0298420078608604 0.11019408085887 STAT1/CTNNB1 2 GO:0097284 hepatocyte apoptotic process 2/320 16/18722 0.0298420078608604 0.11019408085887 KRT8/KRT18 2 GO:1901163 regulation of trophoblast cell migration 2/320 16/18722 0.0298420078608604 0.11019408085887 ARHGDIB/GJA1 2 GO:2000765 regulation of cytoplasmic translation 2/320 16/18722 0.0298420078608604 0.11019408085887 PKM/YBX3 2 GO:2001044 regulation of integrin-mediated signaling pathway 2/320 16/18722 0.0298420078608604 0.11019408085887 FLNA/CD63 2 GO:0051604 protein maturation 10/320 294/18722 0.0303572982316399 0.111435632941354 CTSS/SRGN/ENO1/MYH9/PARP1/DHCR24/PGK1/CTSL/CARD16/SOX4 10 GO:0002287 alpha-beta T cell activation involved in immune response 4/320 69/18722 0.0304126161718678 0.111435632941354 HLA-DRB1/HLA-DRA/ANXA1/HMGB1 4 GO:0002293 alpha-beta T cell differentiation involved in immune response 4/320 69/18722 0.0304126161718678 0.111435632941354 HLA-DRB1/HLA-DRA/ANXA1/HMGB1 4 GO:0009145 purine nucleoside triphosphate biosynthetic process 4/320 69/18722 0.0304126161718678 0.111435632941354 TMSB4X/ALDOA/ENO1/PARP1 4 GO:1901224 positive regulation of NIK/NF-kappaB signaling 4/320 69/18722 0.0304126161718678 0.111435632941354 LAPTM5/HMGB1/RHOA/PDCD4 4 GO:0007266 Rho protein signal transduction 6/320 137/18722 0.0304447626039719 0.111435632941354 EPS8L1/ARHGDIB/CDC42/ITGB1/STMN1/RHOA 6 GO:0030900 forebrain development 12/320 379/18722 0.0304462244098119 0.111435632941354 FLNA/TYROBP/CXCR4/NRP2/C12orf57/ISL1/B2M/TRA2B/LRP2/RHOA/EZH2/CTNNB1 12 GO:0019439 aromatic compound catabolic process 14/320 467/18722 0.0305986802749018 0.111435632941354 VIM/TNFRSF1B/UPP1/APOBEC3A/ZFP36/FUS/SAMHD1/BLVRA/ZFP36L2/SSB/PDE4B/HMOX1/HSPA1A/YBX3 14 GO:0033674 positive regulation of kinase activity 14/320 467/18722 0.0305986802749018 0.111435632941354 PTPRC/IGF2/NCF1/HLA-DRB1/LMO4/CDC42/HMGB1/FLT1/CD74/MAGED1/RHOA/EZH2/DBF4/CKS2 14 GO:0002714 positive regulation of B cell mediated immunity 3/320 40/18722 0.0306821348931714 0.111435632941354 PTPRC/HLA-E/TFRC 3 GO:0002891 positive regulation of immunoglobulin mediated immune response 3/320 40/18722 0.0306821348931714 0.111435632941354 PTPRC/HLA-E/TFRC 3 GO:0044275 cellular carbohydrate catabolic process 3/320 40/18722 0.0306821348931714 0.111435632941354 TPI1/PYGL/HMGB1 3 GO:0045022 early endosome to late endosome transport 3/320 40/18722 0.0306821348931714 0.111435632941354 FLNA/MSN/EZR 3 GO:0070266 necroptotic process 3/320 40/18722 0.0306821348931714 0.111435632941354 CAV1/PYGL/YBX3 3 GO:0071526 semaphorin-plexin signaling pathway 3/320 40/18722 0.0306821348931714 0.111435632941354 FLNA/NRP2/SEMA6D 3 GO:0150077 regulation of neuroinflammatory response 3/320 40/18722 0.0306821348931714 0.111435632941354 PTPRC/TNFRSF1B/CCL3 3 GO:1901020 negative regulation of calcium ion transmembrane transporter activity 3/320 40/18722 0.0306821348931714 0.111435632941354 C4orf3/SRI/GSTO1 3 GO:0001841 neural tube formation 5/320 102/18722 0.0307445841125712 0.111435632941354 LMO4/PFN1/VASP/LRP2/SOX4 5 GO:0010522 regulation of calcium ion transport into cytosol 5/320 102/18722 0.0307445841125712 0.111435632941354 CORO1A/CAV1/CYBA/SRI/GSTO1 5 GO:0035710 CD4-positive, alpha-beta T cell activation 5/320 102/18722 0.0307445841125712 0.111435632941354 HLA-DRB1/HLA-DRA/ANXA1/HMGB1/CTSL 5 GO:1904063 negative regulation of cation transmembrane transport 5/320 102/18722 0.0307445841125712 0.111435632941354 CAV1/C4orf3/SRI/SLC43A2/GSTO1 5 GO:0060415 muscle tissue morphogenesis 4/320 70/18722 0.0318367496443113 0.115293119658453 DSP/ISL1/TGFBR1/LRP2 4 GO:0050728 negative regulation of inflammatory response 7/320 176/18722 0.0319197158108264 0.115492351777876 PTPRC/TNFRSF1B/HLA-DRB1/GPX1/ZFP36/ISL1/PBK 7 GO:0010907 positive regulation of glucose metabolic process 3/320 41/18722 0.0326973640171127 0.117380980120512 IGF2/PMAIP1/HMGB1 3 GO:0032735 positive regulation of interleukin-12 production 3/320 41/18722 0.0326973640171127 0.117380980120512 LAPTM5/ISL1/HMGB1 3 GO:0048634 regulation of muscle organ development 3/320 41/18722 0.0326973640171127 0.117380980120512 IGF2/YBX3/CTNNB1 3 GO:0050856 regulation of T cell receptor signaling pathway 3/320 41/18722 0.0326973640171127 0.117380980120512 LAPTM5/EZR/GBP1 3 GO:0051693 actin filament capping 3/320 41/18722 0.0326973640171127 0.117380980120512 CAPG/CAPZA1/CAPZB 3 GO:0070296 sarcoplasmic reticulum calcium ion transport 3/320 41/18722 0.0326973640171127 0.117380980120512 CCL3/SRI/GSTO1 3 GO:0071470 cellular response to osmotic stress 3/320 41/18722 0.0326973640171127 0.117380980120512 TSPO/EFHD1/YBX3 3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 3/320 41/18722 0.0326973640171127 0.117380980120512 FLNA/MYADM/CDC42 3 GO:1900371 regulation of purine nucleotide biosynthetic process 3/320 41/18722 0.0326973640171127 0.117380980120512 TMSB4X/ENO1/PARP1 3 GO:0051302 regulation of cell division 7/320 177/18722 0.0327684904273814 0.117534203512101 TXNIP/EVI2B/IGF2/LBH/PGF/CDC42/RHOA 7 GO:0010720 positive regulation of cell development 10/320 298/18722 0.0328489248469421 0.117720518185225 TNFRSF1B/TSPO/FLNA/TYROBP/MYADM/CXCR4/FN1/CDC42/LRP2/CTNNB1 10 GO:0032963 collagen metabolic process 5/320 104/18722 0.0330386738911121 0.118016100575185 VIM/CTSS/ITGB1/CTSB/CTSL 5 GO:0003281 ventricular septum development 4/320 71/18722 0.033299442448693 0.118016100575185 LMO4/TGFBR1/LRP2/SOX4 4 GO:0032722 positive regulation of chemokine production 4/320 71/18722 0.033299442448693 0.118016100575185 AIF1/HMGB1/CD74/HMOX1 4 GO:0061515 myeloid cell development 4/320 71/18722 0.033299442448693 0.118016100575185 EVI2B/TYROBP/KLF2/FBN1 4 GO:0009251 glucan catabolic process 2/320 17/18722 0.0334455115618447 0.118016100575185 PYGL/HMGB1 2 GO:0010934 macrophage cytokine production 2/320 17/18722 0.0334455115618447 0.118016100575185 LAPTM5/CD74 2 GO:0010935 regulation of macrophage cytokine production 2/320 17/18722 0.0334455115618447 0.118016100575185 LAPTM5/CD74 2 GO:0016264 gap junction assembly 2/320 17/18722 0.0334455115618447 0.118016100575185 CAV1/GJA1 2 GO:0036035 osteoclast development 2/320 17/18722 0.0334455115618447 0.118016100575185 TYROBP/FBN1 2 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 2/320 17/18722 0.0334455115618447 0.118016100575185 CAV1/PARP14 2 GO:0045591 positive regulation of regulatory T cell differentiation 2/320 17/18722 0.0334455115618447 0.118016100575185 HLA-DRB1/HLA-DRA 2 GO:0060644 mammary gland epithelial cell differentiation 2/320 17/18722 0.0334455115618447 0.118016100575185 LBH/CEBPB 2 GO:0060977 coronary vasculature morphogenesis 2/320 17/18722 0.0334455115618447 0.118016100575185 TGFBR1/LRP2 2 GO:0061158 3'-UTR-mediated mRNA destabilization 2/320 17/18722 0.0334455115618447 0.118016100575185 ZFP36/ZFP36L2 2 GO:0061450 trophoblast cell migration 2/320 17/18722 0.0334455115618447 0.118016100575185 ARHGDIB/GJA1 2 GO:0070875 positive regulation of glycogen metabolic process 2/320 17/18722 0.0334455115618447 0.118016100575185 IGF2/HMGB1 2 GO:2000696 regulation of epithelial cell differentiation involved in kidney development 2/320 17/18722 0.0334455115618447 0.118016100575185 STAT1/CTNNB1 2 GO:2000811 negative regulation of anoikis 2/320 17/18722 0.0334455115618447 0.118016100575185 CAV1/ITGB1 2 GO:0009266 response to temperature stimulus 7/320 178/18722 0.0336322184570984 0.118472571751689 PLAC8/CXCR4/SOD2/ATP2B1/HMOX1/HSPA1A/PDCD6 7 GO:0035265 organ growth 7/320 178/18722 0.0336322184570984 0.118472571751689 IGF2/TGFBR1/PSAP/ANXA6/CDK1/YBX3/GJA1 7 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 5/320 105/18722 0.0342246372047301 0.120456729923292 EPS8L1/CDC42/PFN1/TGFBR1/ACTR3 5 GO:0010950 positive regulation of endopeptidase activity 7/320 179/18722 0.0345109893051692 0.121245249491107 TNFSF10/LAPTM5/PMAIP1/HMGB1/S100A9/RHOA/PDCD6 7 GO:0007520 myoblast fusion 3/320 42/18722 0.0347799878992064 0.121245249491107 CD53/ADAM12/MYH9 3 GO:0010591 regulation of lamellipodium assembly 3/320 42/18722 0.0347799878992064 0.121245249491107 CDC42/CAPZB/ACTR3 3 GO:0010939 regulation of necrotic cell death 3/320 42/18722 0.0347799878992064 0.121245249491107 TSPO/CAV1/YBX3 3 GO:0030808 regulation of nucleotide biosynthetic process 3/320 42/18722 0.0347799878992064 0.121245249491107 TMSB4X/ENO1/PARP1 3 GO:0032689 negative regulation of interferon-gamma production 3/320 42/18722 0.0347799878992064 0.121245249491107 LAPTM5/HLA-DRB1/HMGB1 3 GO:0035019 somatic stem cell population maintenance 3/320 42/18722 0.0347799878992064 0.121245249491107 LBH/ZFP36L2/SOX4 3 GO:0042168 heme metabolic process 3/320 42/18722 0.0347799878992064 0.121245249491107 TSPO/BLVRA/HMOX1 3 GO:0072595 maintenance of protein localization in organelle 3/320 42/18722 0.0347799878992064 0.121245249491107 TSPO/SYNE1/GJA1 3 GO:0030032 lamellipodium assembly 4/320 72/18722 0.0348007903912035 0.121245249491107 CDC42/ITGB1/CAPZB/ACTR3 4 GO:0030330 DNA damage response, signal transduction by p53 class mediator 4/320 72/18722 0.0348007903912035 0.121245249491107 PMAIP1/PTTG1IP/CD74/SOX4 4 GO:0033627 cell adhesion mediated by integrin 4/320 72/18722 0.0348007903912035 0.121245249491107 ITGB2/FBN1/ITGB1/PLPP3 4 GO:2001020 regulation of response to DNA damage stimulus 8/320 219/18722 0.0350333722274485 0.1219527329771 FUS/PMAIP1/HMGB1/DEK/PTTG1IP/CD74/PARP1/PPP1R10 8 GO:0097553 calcium ion transmembrane import into cytosol 6/320 142/18722 0.0353629464463867 0.122942466816713 PTPRC/CORO1A/CCL3/CYBA/SRI/GSTO1 6 GO:0046620 regulation of organ growth 5/320 106/18722 0.0354367081265018 0.122942466816713 IGF2/TGFBR1/CDK1/YBX3/GJA1 5 GO:0071887 leukocyte apoptotic process 5/320 106/18722 0.0354367081265018 0.122942466816713 TSC22D3/ANXA1/CD74/SLC39A10/CTSL 5 GO:0090263 positive regulation of canonical Wnt signaling pathway 5/320 106/18722 0.0354367081265018 0.122942466816713 ZEB2/CAV1/WLS/SOX4/LGR5 5 GO:0072001 renal system development 10/320 302/18722 0.0354808698541153 0.122992411272823 FBN1/TGFBR1/ADAMTS6/STAT1/MAGED1/LRP2/RHOA/CTNNB1/SOX4/LGR5 10 GO:0015849 organic acid transport 10/320 303/18722 0.0361611691063341 0.125245558044738 CROT/SLC16A3/PLIN2/ANXA1/ITGB1/SLC27A2/SLC43A2/EMB/LRP2/GJA1 10 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 4/320 73/18722 0.0363408699255821 0.125607456784575 HLA-DRB1/DYNLL1/SRI/HMGN3 4 GO:0042274 ribosomal small subunit biogenesis 4/320 73/18722 0.0363408699255821 0.125607456784575 RPS27/RPS21/RPS17/RPS28 4 GO:0030010 establishment of cell polarity 6/320 143/18722 0.036404359808213 0.125607456784575 MSN/CDC42/ITGB1/MYH9/RHOA/GJA1 6 GO:0034763 negative regulation of transmembrane transport 6/320 143/18722 0.036404359808213 0.125607456784575 CAV1/C4orf3/OAZ1/SRI/SLC43A2/GSTO1 6 GO:0008406 gonad development 8/320 221/18722 0.036658585611458 0.125607456784575 TNFSF10/FLNA/CYP19A1/TGFBR1/LRP2/IDH1/YBX3/CEBPB 8 GO:0051656 establishment of organelle localization 12/320 390/18722 0.0366620841501902 0.125607456784575 ARMCX3/EZR/RAB17/CDC42/ITGB1/MYH9/HMOX1/STXBP2/ACTR3/CTNNB1/PDCD6/GJA1 12 GO:0005976 polysaccharide metabolic process 5/320 107/18722 0.0366749975873758 0.125607456784575 IGF2/PYGL/PHLDA2/HMGB1/UGP2 5 GO:0010927 cellular component assembly involved in morphogenesis 5/320 107/18722 0.0366749975873758 0.125607456784575 KRT19/KRT8/ACTG1/ITGB1/PLEC 5 GO:0009636 response to toxic substance 9/320 262/18722 0.036772729997483 0.125607456784575 GPX3/CCL3/GPX1/SOD2/CDK1/GSTO1/GPX4/S100A9/SOD3 9 GO:0001709 cell fate determination 3/320 43/18722 0.0369296336949362 0.125607456784575 ISL1/CDC42/CTNNB1 3 GO:0002861 regulation of inflammatory response to antigenic stimulus 3/320 43/18722 0.0369296336949362 0.125607456784575 HLA-DRB1/GPX1/HLA-E 3 GO:0042088 T-helper 1 type immune response 3/320 43/18722 0.0369296336949362 0.125607456784575 HLA-DRB1/ANXA1/HMGB1 3 GO:0120178 steroid hormone biosynthetic process 3/320 43/18722 0.0369296336949362 0.125607456784575 TSPO/CYP11A1/CYP19A1 3 GO:1903793 positive regulation of anion transport 3/320 43/18722 0.0369296336949362 0.125607456784575 ITGB1/TCAF1/CEBPB 3 GO:0002544 chronic inflammatory response 2/320 18/18722 0.0372091428881945 0.125607456784575 S100A9/GJA1 2 GO:0002643 regulation of tolerance induction 2/320 18/18722 0.0372091428881945 0.125607456784575 HLA-B/HMGB1 2 GO:0003128 heart field specification 2/320 18/18722 0.0372091428881945 0.125607456784575 ISL1/LRP2 2 GO:0006595 polyamine metabolic process 2/320 18/18722 0.0372091428881945 0.125607456784575 OAZ1/AZIN1 2 GO:0030889 negative regulation of B cell proliferation 2/320 18/18722 0.0372091428881945 0.125607456784575 MNDA/TYROBP 2 GO:0034134 toll-like receptor 2 signaling pathway 2/320 18/18722 0.0372091428881945 0.125607456784575 CYBA/HMGB1 2 GO:0043217 myelin maintenance 2/320 18/18722 0.0372091428881945 0.125607456784575 CXCR4/PLEC 2 GO:0044247 cellular polysaccharide catabolic process 2/320 18/18722 0.0372091428881945 0.125607456784575 PYGL/HMGB1 2 GO:0048643 positive regulation of skeletal muscle tissue development 2/320 18/18722 0.0372091428881945 0.125607456784575 IGF2/CTNNB1 2 GO:0050665 hydrogen peroxide biosynthetic process 2/320 18/18722 0.0372091428881945 0.125607456784575 CYBA/SOD2 2 GO:0060391 positive regulation of SMAD protein signal transduction 2/320 18/18722 0.0372091428881945 0.125607456784575 TGFBR1/PARP1 2 GO:0060546 negative regulation of necroptotic process 2/320 18/18722 0.0372091428881945 0.125607456784575 CAV1/YBX3 2 GO:0150079 negative regulation of neuroinflammatory response 2/320 18/18722 0.0372091428881945 0.125607456784575 PTPRC/TNFRSF1B 2 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 2/320 18/18722 0.0372091428881945 0.125607456784575 ZFP36/ZFP36L2 2 GO:1901673 regulation of mitotic spindle assembly 2/320 18/18722 0.0372091428881945 0.125607456784575 CCSAP/HSPA1A 2 GO:2000136 regulation of cell proliferation involved in heart morphogenesis 2/320 18/18722 0.0372091428881945 0.125607456784575 ISL1/CTNNB1 2 GO:2000641 regulation of early endosome to late endosome transport 2/320 18/18722 0.0372091428881945 0.125607456784575 MSN/EZR 2 GO:0051260 protein homooligomerization 7/320 182/18722 0.0372384159150784 0.125607456784575 ALDOA/FUS/KCTD12/SAMHD1/SOD2/B2M/VASP 7 GO:0003151 outflow tract morphogenesis 4/320 74/18722 0.0379197384222267 0.127593126352313 NRP2/ISL1/LRP2/CTNNB1 4 GO:0009201 ribonucleoside triphosphate biosynthetic process 4/320 74/18722 0.0379197384222267 0.127593126352313 TMSB4X/ALDOA/ENO1/PARP1 4 GO:0051881 regulation of mitochondrial membrane potential 4/320 74/18722 0.0379197384222267 0.127593126352313 TSPO/BNIP3L/PMAIP1/PARP1 4 GO:0015833 peptide transport 9/320 264/18722 0.0382980968040741 0.128761379979198 HLA-DRB1/ANXA1/DYNLL1/ISL1/SRI/HMGN3/CD74/SOX4/GJA1 9 GO:0021517 ventral spinal cord development 3/320 44/18722 0.0391458791882464 0.131078422046867 LMO4/ISL1/SOX4 3 GO:0031295 T cell costimulation 3/320 44/18722 0.0391458791882464 0.131078422046867 TNFSF13B/CAV1/EFNB1 3 GO:0032881 regulation of polysaccharide metabolic process 3/320 44/18722 0.0391458791882464 0.131078422046867 IGF2/PHLDA2/HMGB1 3 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 3/320 44/18722 0.0391458791882464 0.131078422046867 MSN/CDC42/RHOA 3 GO:0048806 genitalia development 3/320 44/18722 0.0391458791882464 0.131078422046867 DHCR24/LRP2/CTNNB1 3 GO:0032414 positive regulation of ion transmembrane transporter activity 5/320 109/18722 0.0392306336397176 0.131149658737308 TMSB4X/CTSS/IFNGR2/TCAF1/GSTO1 5 GO:0034766 negative regulation of ion transmembrane transport 5/320 109/18722 0.0392306336397176 0.131149658737308 CAV1/C4orf3/SRI/SLC43A2/GSTO1 5 GO:2001259 positive regulation of cation channel activity 4/320 75/18722 0.0395374344472931 0.132068455243504 TMSB4X/CTSS/IFNGR2/GSTO1 4 GO:0008037 cell recognition 8/320 225/18722 0.0400598184626369 0.133705306855909 ALDOA/VCAN/FCN1/CXCR4/MSN/EMB/LY6K/SPESP1 8 GO:0007369 gastrulation 7/320 185/18722 0.0401042084430044 0.133745431223966 ITGB2/MYADM/FN1/WLS/ITGB1/CTNNB1/GJA1 7 GO:0014812 muscle cell migration 5/320 110/18722 0.0405481599219157 0.13489483912899 AIF1/ANXA1/IGFBP3/SEMA6D/RHOA 5 GO:0016331 morphogenesis of embryonic epithelium 6/320 147/18722 0.0407658510390102 0.13489483912899 LMO4/PFN1/VASP/LRP2/CTNNB1/SOX4 6 GO:0051480 regulation of cytosolic calcium ion concentration 11/320 353/18722 0.0410245445649762 0.13489483912899 PTPRC/CORO1A/CXCR4/CAV1/CCL3/CYBA/ATP2B1/HMGB1/SRI/GSTO1/GJA1 11 GO:0008217 regulation of blood pressure 7/320 186/18722 0.0410905734572292 0.13489483912899 CYBA/SOD2/ATP2B1/NAMPT/HMOX1/RHOA/GJA1 7 GO:0031345 negative regulation of cell projection organization 7/320 186/18722 0.0410905734572292 0.13489483912899 VIM/FLNA/SEMA6D/B2M/CAPZB/RHOA/ID1 7 GO:0000028 ribosomal small subunit assembly 2/320 19/18722 0.0411264121108611 0.13489483912899 RPS27/RPS28 2 GO:0002281 macrophage activation involved in immune response 2/320 19/18722 0.0411264121108611 0.13489483912899 TYROBP/HMGB1 2 GO:0002902 regulation of B cell apoptotic process 2/320 19/18722 0.0411264121108611 0.13489483912899 CD74/SLC39A10 2 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate 2/320 19/18722 0.0411264121108611 0.13489483912899 APOBEC3A/TOP2A 2 GO:0051444 negative regulation of ubiquitin-protein transferase activity 2/320 19/18722 0.0411264121108611 0.13489483912899 RPL23/RPL37 2 GO:0061323 cell proliferation involved in heart morphogenesis 2/320 19/18722 0.0411264121108611 0.13489483912899 ISL1/CTNNB1 2 GO:0062099 negative regulation of programmed necrotic cell death 2/320 19/18722 0.0411264121108611 0.13489483912899 CAV1/YBX3 2 GO:0072077 renal vesicle morphogenesis 2/320 19/18722 0.0411264121108611 0.13489483912899 STAT1/CTNNB1 2 GO:0086014 atrial cardiac muscle cell action potential 2/320 19/18722 0.0411264121108611 0.13489483912899 FLNA/GJA1 2 GO:0086026 atrial cardiac muscle cell to AV node cell signaling 2/320 19/18722 0.0411264121108611 0.13489483912899 FLNA/GJA1 2 GO:0086066 atrial cardiac muscle cell to AV node cell communication 2/320 19/18722 0.0411264121108611 0.13489483912899 FLNA/GJA1 2 GO:1903978 regulation of microglial cell activation 2/320 19/18722 0.0411264121108611 0.13489483912899 PTPRC/CCL3 2 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation 2/320 19/18722 0.0411264121108611 0.13489483912899 HLA-A/HLA-E 2 GO:0014823 response to activity 4/320 76/18722 0.0411939780510168 0.13489483912899 CXCR4/CYBA/SOD2/CDK1 4 GO:0045685 regulation of glial cell differentiation 4/320 76/18722 0.0411939780510168 0.13489483912899 TNFRSF1B/CXCR4/CDK1/CTNNB1 4 GO:0086001 cardiac muscle cell action potential 4/320 76/18722 0.0411939780510168 0.13489483912899 FLNA/CAV1/DSP/GJA1 4 GO:0030835 negative regulation of actin filament depolymerization 3/320 45/18722 0.0414282552891308 0.13489483912899 CAPG/CAPZA1/CAPZB 3 GO:0030850 prostate gland development 3/320 45/18722 0.0414282552891308 0.13489483912899 ANXA1/PSAP/CTNNB1 3 GO:0035272 exocrine system development 3/320 45/18722 0.0414282552891308 0.13489483912899 IGF2/WLS/CDC42 3 GO:0035987 endodermal cell differentiation 3/320 45/18722 0.0414282552891308 0.13489483912899 ITGB2/FN1/CTNNB1 3 GO:0045933 positive regulation of muscle contraction 3/320 45/18722 0.0414282552891308 0.13489483912899 ENO1/GSTO1/RHOA 3 GO:0048538 thymus development 3/320 45/18722 0.0414282552891308 0.13489483912899 LMO4/TGFBR1/CTNNB1 3 GO:0071364 cellular response to epidermal growth factor stimulus 3/320 45/18722 0.0414282552891308 0.13489483912899 ZFP36/ZFP36L2/ID1 3 GO:1904646 cellular response to amyloid-beta 3/320 45/18722 0.0414282552891308 0.13489483912899 NAMPT/PARP1/GJA1 3 GO:2000273 positive regulation of signaling receptor activity 3/320 45/18722 0.0414282552891308 0.13489483912899 NCF1/ITGB1/IFNGR2 3 GO:0051348 negative regulation of transferase activity 9/320 268/18722 0.0414771186522867 0.134947601788385 PTPRC/CAV1/RPL23/RPL37/ZFP36/MLLT1/PLEC/HSPB1/PDCD4 9 GO:0045137 development of primary sexual characteristics 8/320 227/18722 0.0418368616966729 0.136010946129545 TNFSF10/FLNA/CYP19A1/TGFBR1/LRP2/IDH1/YBX3/CEBPB 8 GO:0010212 response to ionizing radiation 6/320 148/18722 0.0419056104278062 0.136020410280986 PTPRC/CYBA/GPX1/ANXA1/NAMPT/PARP1 6 GO:0035148 tube formation 6/320 148/18722 0.0419056104278062 0.136020410280986 LMO4/PFN1/VASP/LRP2/CTNNB1/SOX4 6 GO:0070588 calcium ion transmembrane transport 10/320 312/18722 0.0426956911649439 0.138476134924292 PTPRC/CORO1A/C4orf3/CCL3/CYBA/ATP2B1/SRI/PDE4B/ANXA6/GSTO1 10 GO:0002200 somatic diversification of immune receptors 4/320 77/18722 0.0428893710645212 0.138886270563167 PTPRC/SAMHD1/HMGB1/TFRC 4 GO:0048644 muscle organ morphogenesis 4/320 77/18722 0.0428893710645212 0.138886270563167 DSP/ISL1/TGFBR1/LRP2 4 GO:0045787 positive regulation of cell cycle 10/320 313/18722 0.0434683459126959 0.140650904707329 AIF1/IGF2/ANXA1/CDC42/PPP1R10/CDK1/RHOA/EZH2/DBF4/CKS2 10 GO:0031294 lymphocyte costimulation 3/320 46/18722 0.0437762484489191 0.140874967749948 TNFSF13B/CAV1/EFNB1 3 GO:0043300 regulation of leukocyte degranulation 3/320 46/18722 0.0437762484489191 0.140874967749948 ITGB2/HMOX1/STXBP2 3 GO:0050919 negative chemotaxis 3/320 46/18722 0.0437762484489191 0.140874967749948 NRP2/SEMA6D/RHOA 3 GO:0060976 coronary vasculature development 3/320 46/18722 0.0437762484489191 0.140874967749948 TGFBR1/ADAMTS6/LRP2 3 GO:0061028 establishment of endothelial barrier 3/320 46/18722 0.0437762484489191 0.140874967749948 MYADM/MSN/EZR 3 GO:0090329 regulation of DNA-dependent DNA replication 3/320 46/18722 0.0437762484489191 0.140874967749948 RFC3/GMNN/DBF4 3 GO:2000107 negative regulation of leukocyte apoptotic process 3/320 46/18722 0.0437762484489191 0.140874967749948 TSC22D3/CD74/SLC39A10 3 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 4/320 78/18722 0.0446235974044051 0.142440105535548 LAPTM5/PMAIP1/S100A9/PDCD6 4 GO:0030500 regulation of bone mineralization 4/320 78/18722 0.0446235974044051 0.142440105535548 SRGN/CCL3/ISG15/ATP2B1 4 GO:0090559 regulation of membrane permeability 4/320 78/18722 0.0446235974044051 0.142440105535548 LAPTM5/BNIP3L/PMAIP1/HSPA1A 4 GO:0006874 cellular calcium ion homeostasis 13/320 448/18722 0.0451351056169311 0.142440105535548 PTPRC/CORO1A/CXCR4/CAV1/CCL3/CYBA/STC2/ATP2B1/HMGB1/SRI/ANXA6/GSTO1/GJA1 13 GO:0000272 polysaccharide catabolic process 2/320 20/18722 0.045191003348499 0.142440105535548 PYGL/HMGB1 2 GO:0002834 regulation of response to tumor cell 2/320 20/18722 0.045191003348499 0.142440105535548 HLA-DRB1/HMGB1 2 GO:0002837 regulation of immune response to tumor cell 2/320 20/18722 0.045191003348499 0.142440105535548 HLA-DRB1/HMGB1 2 GO:0003215 cardiac right ventricle morphogenesis 2/320 20/18722 0.045191003348499 0.142440105535548 ISL1/SOX4 2 GO:0006700 C21-steroid hormone biosynthetic process 2/320 20/18722 0.045191003348499 0.142440105535548 TSPO/CYP11A1 2 GO:0010042 response to manganese ion 2/320 20/18722 0.045191003348499 0.142440105535548 TSPO/SOD2 2 GO:0010523 negative regulation of calcium ion transport into cytosol 2/320 20/18722 0.045191003348499 0.142440105535548 SRI/GSTO1 2 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate 2/320 20/18722 0.045191003348499 0.142440105535548 APOBEC3A/TOP2A 2 GO:0042359 vitamin D metabolic process 2/320 20/18722 0.045191003348499 0.142440105535548 CYP11A1/LRP2 2 GO:0045063 T-helper 1 cell differentiation 2/320 20/18722 0.045191003348499 0.142440105535548 ANXA1/HMGB1 2 GO:0045844 positive regulation of striated muscle tissue development 2/320 20/18722 0.045191003348499 0.142440105535548 IGF2/CTNNB1 2 GO:0046629 gamma-delta T cell activation 2/320 20/18722 0.045191003348499 0.142440105535548 PTPRC/SOX4 2 GO:0048636 positive regulation of muscle organ development 2/320 20/18722 0.045191003348499 0.142440105535548 IGF2/CTNNB1 2 GO:0051900 regulation of mitochondrial depolarization 2/320 20/18722 0.045191003348499 0.142440105535548 TSPO/PARP1 2 GO:0060231 mesenchymal to epithelial transition 2/320 20/18722 0.045191003348499 0.142440105535548 STAT1/CTNNB1 2 GO:0060339 negative regulation of type I interferon-mediated signaling pathway 2/320 20/18722 0.045191003348499 0.142440105535548 ISG15/SAMHD1 2 GO:0071243 cellular response to arsenic-containing substance 2/320 20/18722 0.045191003348499 0.142440105535548 HMOX1/GSTO1 2 GO:0072087 renal vesicle development 2/320 20/18722 0.045191003348499 0.142440105535548 STAT1/CTNNB1 2 GO:0072567 chemokine (C-X-C motif) ligand 2 production 2/320 20/18722 0.045191003348499 0.142440105535548 HMGB1/CD74 2 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production 2/320 20/18722 0.045191003348499 0.142440105535548 HMGB1/CD74 2 GO:2000678 negative regulation of transcription regulatory region DNA binding 2/320 20/18722 0.045191003348499 0.142440105535548 TMSB4X/SRI 2 GO:0009566 fertilization 7/320 190/18722 0.0451933635907801 0.142440105535548 ALDOA/MYH9/CLIC4/CDK1/LY6K/YBX3/SPESP1 7 GO:0046390 ribose phosphate biosynthetic process 7/320 190/18722 0.0451933635907801 0.142440105535548 TMSB4X/ALDOA/UPP1/ENO1/PYGL/PARP1/PPT1 7 GO:0051052 regulation of DNA metabolic process 11/320 359/18722 0.0453475932467206 0.142796338124099 PTPRC/MBD3/FUS/HMGB1/DEK/PARP1/PPP1R10/RFC3/CTNNB1/GJA1/TFRC 11 GO:0030902 hindbrain development 6/320 151/18722 0.0454446235801527 0.142796338124099 AIF1/FLNA/WLS/ITGB1/EZH2/CTNNB1 6 GO:0043535 regulation of blood vessel endothelial cell migration 6/320 151/18722 0.0454446235801527 0.142796338124099 TMSB4X/ANXA1/HMGB1/HMOX1/RHOA/HSPB1 6 GO:1904064 positive regulation of cation transmembrane transport 6/320 151/18722 0.0454446235801527 0.142796338124099 TMSB4X/CTSS/FLNA/SRI/IFNGR2/GSTO1 6 GO:0046942 carboxylic acid transport 9/320 273/18722 0.0456956856870311 0.143476119497578 SLC16A3/SLC6A8/ANXA1/ITGB1/PSAP/SLC43A2/EMB/LRP2/GJA1 9 GO:0002244 hematopoietic progenitor cell differentiation 5/320 114/18722 0.0460846917396427 0.144040905643401 PTPRC/PLEK/FLT1/SOX4/TOP2A 5 GO:1903008 organelle disassembly 5/320 114/18722 0.0460846917396427 0.144040905643401 TSPO/BNIP3L/CDK1/UBA5/VPS13C 5 GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 3/320 47/18722 0.0461893029955242 0.144040905643401 CYBA/SOD2/RHOA 3 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 3/320 47/18722 0.0461893029955242 0.144040905643401 LAPTM5/HSPA1A/CARD16 3 GO:0097028 dendritic cell differentiation 3/320 47/18722 0.0461893029955242 0.144040905643401 HLA-B/HMGB1/CEBPB 3 GO:0097300 programmed necrotic cell death 3/320 47/18722 0.0461893029955242 0.144040905643401 CAV1/PYGL/YBX3 3 GO:0101023 vascular endothelial cell proliferation 3/320 47/18722 0.0461893029955242 0.144040905643401 IGF2/HMGB1/FLT1 3 GO:1903170 negative regulation of calcium ion transmembrane transport 3/320 47/18722 0.0461893029955242 0.144040905643401 C4orf3/SRI/GSTO1 3 GO:1905562 regulation of vascular endothelial cell proliferation 3/320 47/18722 0.0461893029955242 0.144040905643401 IGF2/HMGB1/FLT1 3 GO:0051279 regulation of release of sequestered calcium ion into cytosol 4/320 79/18722 0.0463966233844357 0.14457831660972 CORO1A/CYBA/SRI/GSTO1 4 GO:0010506 regulation of autophagy 10/320 317/18722 0.0466541522269878 0.145193826305344 GAPDH/TSPO/MTDH/BNIP3L/HMGB1/PSAP/NAMPT/HMOX1/VPS13C/HSPB1 10 GO:0051092 positive regulation of NF-kappaB transcription factor activity 6/320 152/18722 0.0466644243304686 0.145193826305344 CAV1/MTDH/S100A9/HSPA1A/CARD16/TFRC 6 GO:0032872 regulation of stress-activated MAPK cascade 7/320 192/18722 0.047340022737152 0.147185081978865 NCF1/PAGE4/EZR/CDC42/HMGB1/PBK/PDCD4 7 GO:0071675 regulation of mononuclear cell migration 5/320 115/18722 0.047535713383269 0.147571425769848 AIF1/MSN/CCL3/HMGB1/RHOA 5 GO:1901989 positive regulation of cell cycle phase transition 5/320 115/18722 0.047535713383269 0.147571425769848 AIF1/ANXA1/PPP1R10/CDK1/EZH2 5 GO:0034655 nucleobase-containing compound catabolic process 12/320 407/18722 0.0479583765127987 0.148771780593757 VIM/TNFRSF1B/UPP1/APOBEC3A/ZFP36/FUS/SAMHD1/ZFP36L2/SSB/PDE4B/HSPA1A/YBX3 12 GO:0007204 positive regulation of cytosolic calcium ion concentration 10/320 319/18722 0.0483047195655469 0.149733759373473 PTPRC/CORO1A/CXCR4/CAV1/CCL3/CYBA/HMGB1/SRI/GSTO1/GJA1 10 GO:0007565 female pregnancy 7/320 193/18722 0.0484373660846544 0.150032381305691 ARHGDIB/FBLN1/PGF/STC2/NAMPT/CTSB/GJA1 7 GO:0035036 sperm-egg recognition 3/320 48/18722 0.0486668233908585 0.150404872289474 ALDOA/LY6K/SPESP1 3 GO:0048146 positive regulation of fibroblast proliferation 3/320 48/18722 0.0486668233908585 0.150404872289474 FN1/S100A6/CD74 3 GO:1905710 positive regulation of membrane permeability 3/320 48/18722 0.0486668233908585 0.150404872289474 LAPTM5/BNIP3L/HSPA1A 3 GO:0030518 intracellular steroid hormone receptor signaling pathway 5/320 116/18722 0.0490135743786705 0.150855473700917 LBH/ISL1/PARP1/UBA5/RHOA 5 GO:0033559 unsaturated fatty acid metabolic process 5/320 116/18722 0.0490135743786705 0.150855473700917 CYP2J2/GPX1/ANXA1/CD74/GPX4 5 GO:0006925 inflammatory cell apoptotic process 2/320 21/18722 0.0493967705511474 0.150855473700917 ANXA1/CTSL 2 GO:0030502 negative regulation of bone mineralization 2/320 21/18722 0.0493967705511474 0.150855473700917 SRGN/CCL3 2 GO:0032516 positive regulation of phosphoprotein phosphatase activity 2/320 21/18722 0.0493967705511474 0.150855473700917 PTPRC/SLC39A10 2 GO:0042454 ribonucleoside catabolic process 2/320 21/18722 0.0493967705511474 0.150855473700917 UPP1/APOBEC3A 2 GO:0045056 transcytosis 2/320 21/18722 0.0493967705511474 0.150855473700917 RAB17/LRP2 2 GO:0046597 negative regulation of viral entry into host cell 2/320 21/18722 0.0493967705511474 0.150855473700917 IFITM2/FCN1 2 GO:0048714 positive regulation of oligodendrocyte differentiation 2/320 21/18722 0.0493967705511474 0.150855473700917 TNFRSF1B/CXCR4 2 GO:0051767 nitric-oxide synthase biosynthetic process 2/320 21/18722 0.0493967705511474 0.150855473700917 NAMPT/STAT1 2 GO:0051769 regulation of nitric-oxide synthase biosynthetic process 2/320 21/18722 0.0493967705511474 0.150855473700917 NAMPT/STAT1 2 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 2/320 21/18722 0.0493967705511474 0.150855473700917 LAPTM5/CD74 2 GO:0090026 positive regulation of monocyte chemotaxis 2/320 21/18722 0.0493967705511474 0.150855473700917 AIF1/HMGB1 2 GO:1901863 positive regulation of muscle tissue development 2/320 21/18722 0.0493967705511474 0.150855473700917 IGF2/CTNNB1 2 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 2/320 21/18722 0.0493967705511474 0.150855473700917 PTTG1IP/CD74 2 GO:1903427 negative regulation of reactive oxygen species biosynthetic process 2/320 21/18722 0.0493967705511474 0.150855473700917 PAGE4/RHOA 2 GO:0045930 negative regulation of mitotic cell cycle 8/320 235/18722 0.0494652499916414 0.150953037640666 TIMP2/BTG3/ZFP36L2/PPP1R10/CDK1/EZH2/CTNNB1/SOX4 8 GO:2000106 regulation of leukocyte apoptotic process 4/320 81/18722 0.0500588534205561 0.152651795080249 TSC22D3/ANXA1/CD74/SLC39A10 4 GO:0006606 protein import into nucleus 6/320 155/18722 0.050445005934692 0.15359040431534 TXNIP/FLNA/RPL23/PTTG1IP/PPP1R10/CDK1 6 GO:0051147 regulation of muscle cell differentiation 6/320 155/18722 0.050445005934692 0.15359040431534 IGF2/SOD2/MORF4L2/BHLHE41/EZH2/PDCD4 6 GO:0030072 peptide hormone secretion 8/320 236/18722 0.0504781628896979 0.15359040431534 HLA-DRB1/ANXA1/DYNLL1/ISL1/SRI/HMGN3/SOX4/GJA1 8 GO:0070302 regulation of stress-activated protein kinase signaling cascade 7/320 195/18722 0.0506803323921982 0.154092077589818 NCF1/PAGE4/EZR/CDC42/HMGB1/PBK/PDCD4 7 GO:0002762 negative regulation of myeloid leukocyte differentiation 3/320 49/18722 0.0512081764125711 0.154446850318791 CCL3/FBN1/CTNNB1 3 GO:0006778 porphyrin-containing compound metabolic process 3/320 49/18722 0.0512081764125711 0.154446850318791 TSPO/BLVRA/HMOX1 3 GO:0006953 acute-phase response 3/320 49/18722 0.0512081764125711 0.154446850318791 SERPINA1/FN1/CEBPB 3 GO:0009409 response to cold 3/320 49/18722 0.0512081764125711 0.154446850318791 PLAC8/SOD2/ATP2B1 3 GO:0021515 cell differentiation in spinal cord 3/320 49/18722 0.0512081764125711 0.154446850318791 LMO4/ISL1/SOX4 3 GO:0030225 macrophage differentiation 3/320 49/18722 0.0512081764125711 0.154446850318791 HLA-DRB1/CDC42/PARP1 3 GO:0046580 negative regulation of Ras protein signal transduction 3/320 49/18722 0.0512081764125711 0.154446850318791 TIMP2/ITGB1/STMN1 3 GO:0050832 defense response to fungus 3/320 49/18722 0.0512081764125711 0.154446850318791 GAPDH/COTL1/S100A9 3 GO:0070169 positive regulation of biomineral tissue development 3/320 49/18722 0.0512081764125711 0.154446850318791 ISG15/ATP2B1/CEBPB 3 GO:0070849 response to epidermal growth factor 3/320 49/18722 0.0512081764125711 0.154446850318791 ZFP36/ZFP36L2/ID1 3 GO:0072091 regulation of stem cell proliferation 3/320 49/18722 0.0512081764125711 0.154446850318791 PTPRC/FBLN1/GJA1 3 GO:0090276 regulation of peptide hormone secretion 7/320 196/18722 0.0518260479910074 0.1561963751268 HLA-DRB1/DYNLL1/ISL1/SRI/HMGN3/SOX4/GJA1 7 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 4/320 82/18722 0.051947904981909 0.156335574206299 GPX1/PMAIP1/TIMP3/HMOX1 4 GO:0060395 SMAD protein signal transduction 4/320 82/18722 0.051947904981909 0.156335574206299 VIM/TGFBR1/JUN/PARP1 4 GO:0051403 stress-activated MAPK cascade 8/320 239/18722 0.0535971282721135 0.159966941409664 NCF1/PAGE4/EZR/ZFP36/CDC42/HMGB1/PBK/PDCD4 8 GO:0030282 bone mineralization 5/320 119/18722 0.0536084289617608 0.159966941409664 SRGN/CCL3/ISG15/ATP2B1/SNX10 5 GO:0031398 positive regulation of protein ubiquitination 5/320 119/18722 0.0536084289617608 0.159966941409664 LAPTM5/CAV1/ARRDC3/PTTG1IP/PDCD6 5 GO:0002053 positive regulation of mesenchymal cell proliferation 2/320 22/18722 0.0537377335697347 0.159966941409664 STAT1/CTNNB1 2 GO:0002220 innate immune response activating cell surface receptor signaling pathway 2/320 22/18722 0.0537377335697347 0.159966941409664 FCN1/TYROBP 2 GO:0032069 regulation of nuclease activity 2/320 22/18722 0.0537377335697347 0.159966941409664 HMGB1/HSPA1A 2 GO:0032727 positive regulation of interferon-alpha production 2/320 22/18722 0.0537377335697347 0.159966941409664 HMGB1/STAT1 2 GO:0032816 positive regulation of natural killer cell activation 2/320 22/18722 0.0537377335697347 0.159966941409664 TYROBP/HLA-E 2 GO:0035024 negative regulation of Rho protein signal transduction 2/320 22/18722 0.0537377335697347 0.159966941409664 ITGB1/STMN1 2 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation 2/320 22/18722 0.0537377335697347 0.159966941409664 ANXA1/HMGB1 2 GO:0045061 thymic T cell selection 2/320 22/18722 0.0537377335697347 0.159966941409664 PTPRC/CD74 2 GO:0060563 neuroepithelial cell differentiation 2/320 22/18722 0.0537377335697347 0.159966941409664 SOX4/CEBPB 2 GO:1900120 regulation of receptor binding 2/320 22/18722 0.0537377335697347 0.159966941409664 PHLDA2/B2M 2 GO:0002448 mast cell mediated immunity 3/320 50/18722 0.0538126932622054 0.159966941409664 SERPINB9/HMOX1/STXBP2 3 GO:0002639 positive regulation of immunoglobulin production 3/320 50/18722 0.0538126932622054 0.159966941409664 PTPRC/HLA-E/TFRC 3 GO:0019083 viral transcription 3/320 50/18722 0.0538126932622054 0.159966941409664 CCL3/ZFP36/JUN 3 GO:0110151 positive regulation of biomineralization 3/320 50/18722 0.0538126932622054 0.159966941409664 ISG15/ATP2B1/CEBPB 3 GO:0051899 membrane depolarization 4/320 83/18722 0.0538754518570372 0.160038365976476 TSPO/CAV1/JUN/PARP1 4 GO:0032411 positive regulation of transporter activity 5/320 120/18722 0.055193842524928 0.16383689462141 TMSB4X/CTSS/IFNGR2/TCAF1/GSTO1 5 GO:0051170 import into nucleus 6/320 159/18722 0.0557701796622636 0.165047618523824 TXNIP/FLNA/RPL23/PTTG1IP/PPP1R10/CDK1 6 GO:1903169 regulation of calcium ion transmembrane transport 6/320 159/18722 0.0557701796622636 0.165047618523824 CORO1A/C4orf3/CYBA/SRI/PDE4B/GSTO1 6 GO:0006970 response to osmotic stress 4/320 84/18722 0.0558413772256305 0.165047618523824 TSC22D3/TSPO/EFHD1/YBX3 4 GO:0010660 regulation of muscle cell apoptotic process 4/320 84/18722 0.0558413772256305 0.165047618523824 SOD2/HMOX1/PPP1R10/PDCD4 4 GO:0042310 vasoconstriction 4/320 84/18722 0.0558413772256305 0.165047618523824 CAV1/ATP2B1/RHOA/GJA1 4 GO:0042440 pigment metabolic process 4/320 84/18722 0.0558413772256305 0.165047618523824 ZEB2/TSPO/BLVRA/HMOX1 4 GO:0007409 axonogenesis 12/320 418/18722 0.0564270642512034 0.166220799899381 FN1/NRP2/EFNB1/S100A6/C12orf57/ISL1/ITGB1/STMN1/SEMA6D/EMB/VASP/ACTB 12 GO:0021872 forebrain generation of neurons 3/320 51/18722 0.0564796716018225 0.166220799899381 NRP2/B2M/RHOA 3 GO:0032873 negative regulation of stress-activated MAPK cascade 3/320 51/18722 0.0564796716018225 0.166220799899381 EZR/PBK/PDCD4 3 GO:0051293 establishment of spindle localization 3/320 51/18722 0.0564796716018225 0.166220799899381 ITGB1/MYH9/GJA1 3 GO:0060043 regulation of cardiac muscle cell proliferation 3/320 51/18722 0.0564796716018225 0.166220799899381 TGFBR1/CDK1/GJA1 3 GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 3/320 51/18722 0.0564796716018225 0.166220799899381 EZR/PBK/PDCD4 3 GO:0071902 positive regulation of protein serine/threonine kinase activity 7/320 200/18722 0.05657141261379 0.166372296740342 IGF2/FLT1/MAGED1/RHOA/EZH2/DBF4/CKS2 7 GO:0042752 regulation of circadian rhythm 5/320 121/18722 0.056806152908478 0.166825176842808 BHLHE40/CDK1/MAGED1/EZH2/TOP2A 5 GO:1904019 epithelial cell apoptotic process 5/320 121/18722 0.056806152908478 0.166825176842808 KRT8/ZFP36/KRT18/HMOX1/PDCD4 5 GO:0009142 nucleoside triphosphate biosynthetic process 4/320 85/18722 0.057845548649393 0.168664630468104 TMSB4X/ALDOA/ENO1/PARP1 4 GO:0048638 regulation of developmental growth 10/320 330/18722 0.0580843791664761 0.168664630468104 PLAC8/IGF2/CXCR4/FN1/EZR/TGFBR1/SEMA6D/CDK1/YBX3/GJA1 10 GO:0002363 alpha-beta T cell lineage commitment 2/320 23/18722 0.0582080743096604 0.168664630468104 CTSL/RHOA 2 GO:0002758 innate immune response-activating signal transduction 2/320 23/18722 0.0582080743096604 0.168664630468104 FCN1/TYROBP 2 GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 2/320 23/18722 0.0582080743096604 0.168664630468104 CYBA/RHOA 2 GO:0003283 atrial septum development 2/320 23/18722 0.0582080743096604 0.168664630468104 ISL1/SOX4 2 GO:0006929 substrate-dependent cell migration 2/320 23/18722 0.0582080743096604 0.168664630468104 PTPRC/FN1 2 GO:0018279 protein N-linked glycosylation via asparagine 2/320 23/18722 0.0582080743096604 0.168664630468104 UBE2J1/TUSC3 2 GO:0019430 removal of superoxide radicals 2/320 23/18722 0.0582080743096604 0.168664630468104 SOD2/SOD3 2 GO:0030539 male genitalia development 2/320 23/18722 0.0582080743096604 0.168664630468104 DHCR24/CTNNB1 2 GO:0031338 regulation of vesicle fusion 2/320 23/18722 0.0582080743096604 0.168664630468104 CORO1A/ANXA1 2 GO:0042026 protein refolding 2/320 23/18722 0.0582080743096604 0.168664630468104 B2M/HSPA1A 2 GO:0043931 ossification involved in bone maturation 2/320 23/18722 0.0582080743096604 0.168664630468104 SNX10/RHOA 2 GO:0045723 positive regulation of fatty acid biosynthetic process 2/320 23/18722 0.0582080743096604 0.168664630468104 ANXA1/CD74 2 GO:0051882 mitochondrial depolarization 2/320 23/18722 0.0582080743096604 0.168664630468104 TSPO/PARP1 2 GO:0060143 positive regulation of syncytium formation by plasma membrane fusion 2/320 23/18722 0.0582080743096604 0.168664630468104 CD53/TYROBP 2 GO:0060547 negative regulation of necrotic cell death 2/320 23/18722 0.0582080743096604 0.168664630468104 CAV1/YBX3 2 GO:1904666 regulation of ubiquitin protein ligase activity 2/320 23/18722 0.0582080743096604 0.168664630468104 RPL23/RPL37 2 GO:2000737 negative regulation of stem cell differentiation 2/320 23/18722 0.0582080743096604 0.168664630468104 LBH/ZFP36L2 2 GO:0002688 regulation of leukocyte chemotaxis 5/320 122/18722 0.0584453477631363 0.169233480698864 AIF1/CCL3/PGF/HMGB1/CD74 5 GO:0019216 regulation of lipid metabolic process 10/320 331/18722 0.0590331890457697 0.17081592236493 TSPO/CAV1/ANXA1/LACTB/CDC42/FLT1/CD74/PSAP/NPC2/IDH1 10 GO:0021545 cranial nerve development 3/320 52/18722 0.0592083775210881 0.170844284858335 NRP2/ISL1/CTNNB1 3 GO:0030514 negative regulation of BMP signaling pathway 3/320 52/18722 0.0592083775210881 0.170844284858335 HTRA1/FBN1/LRP2 3 GO:0048260 positive regulation of receptor-mediated endocytosis 3/320 52/18722 0.0592083775210881 0.170844284858335 CD63/B2M/PPT1 3 GO:0051496 positive regulation of stress fiber assembly 3/320 52/18722 0.0592083775210881 0.170844284858335 CDC42/TGFBR1/RHOA 3 GO:0015908 fatty acid transport 4/320 86/18722 0.0598878184167545 0.172323444079408 CROT/PLIN2/ANXA1/SLC27A2 4 GO:0022406 membrane docking 4/320 86/18722 0.0598878184167545 0.172323444079408 PLEK/MSN/EZR/STXBP2 4 GO:0032413 negative regulation of ion transmembrane transporter activity 4/320 86/18722 0.0598878184167545 0.172323444079408 CAV1/C4orf3/SRI/GSTO1 4 GO:0035023 regulation of Rho protein signal transduction 4/320 86/18722 0.0598878184167545 0.172323444079408 EPS8L1/ARHGDIB/ITGB1/STMN1 4 GO:0021953 central nervous system neuron differentiation 6/320 162/18722 0.0599784706406862 0.172464189761528 NRP2/LMO4/C12orf57/ISL1/B2M/SOX4 6 GO:0006690 icosanoid metabolic process 5/320 123/18722 0.0601114069511835 0.172726240279757 CYP2J2/GPX1/ANXA1/CD74/GPX4 5 GO:0098656 anion transmembrane transport 8/320 245/18722 0.0601993773126067 0.172858809628694 SLC16A3/SLC6A8/ITGB1/SLC43A2/TCAF1/EMB/LRP2/GJA1 8 GO:0072331 signal transduction by p53 class mediator 6/320 163/18722 0.0614221783655236 0.176247528476627 RPL23/RPL37/PMAIP1/PTTG1IP/CD74/SOX4 6 GO:0044070 regulation of anion transport 4/320 87/18722 0.0619680238902087 0.176917080116522 ITGB1/SLC43A2/TCAF1/CEBPB 4 GO:1900182 positive regulation of protein localization to nucleus 4/320 87/18722 0.0619680238902087 0.176917080116522 FLNA/PARP1/CDK1/TFRC 4 GO:1901879 regulation of protein depolymerization 4/320 87/18722 0.0619680238902087 0.176917080116522 PLEK/CAPG/CAPZA1/CAPZB 4 GO:2000177 regulation of neural precursor cell proliferation 4/320 87/18722 0.0619680238902087 0.176917080116522 FLNA/LRP2/RHOA/CTNNB1 4 GO:0008347 glial cell migration 3/320 53/18722 0.0619980474367675 0.176917080116522 TSPO/CCL3/CTNNB1 3 GO:0033059 cellular pigmentation 3/320 53/18722 0.0619980474367675 0.176917080116522 ZEB2/RAB17/CD63 3 GO:0051438 regulation of ubiquitin-protein transferase activity 3/320 53/18722 0.0619980474367675 0.176917080116522 RPL23/RPL37/ARRDC3 3 GO:2000772 regulation of cellular senescence 3/320 53/18722 0.0619980474367675 0.176917080116522 NEK6/NAMPT/B2M 3 GO:0001783 B cell apoptotic process 2/320 24/18722 0.0628021329667426 0.177007150662585 CD74/SLC39A10 2 GO:0002726 positive regulation of T cell cytokine production 2/320 24/18722 0.0628021329667426 0.177007150662585 HLA-A/B2M 2 GO:0006213 pyrimidine nucleoside metabolic process 2/320 24/18722 0.0628021329667426 0.177007150662585 UPP1/APOBEC3A 2 GO:0007035 vacuolar acidification 2/320 24/18722 0.0628021329667426 0.177007150662585 CLIC4/PPT1 2 GO:0018196 peptidyl-asparagine modification 2/320 24/18722 0.0628021329667426 0.177007150662585 UBE2J1/TUSC3 2 GO:0030810 positive regulation of nucleotide biosynthetic process 2/320 24/18722 0.0628021329667426 0.177007150662585 TMSB4X/ENO1 2 GO:0032528 microvillus organization 2/320 24/18722 0.0628021329667426 0.177007150662585 FXYD5/EZR 2 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress 2/320 24/18722 0.0628021329667426 0.177007150662585 KLF2/CEBPB 2 GO:0036010 protein localization to endosome 2/320 24/18722 0.0628021329667426 0.177007150662585 MSN/EZR 2 GO:0050687 negative regulation of defense response to virus 2/320 24/18722 0.0628021329667426 0.177007150662585 FGL2/HTRA1 2 GO:0060479 lung cell differentiation 2/320 24/18722 0.0628021329667426 0.177007150662585 KLF2/CTNNB1 2 GO:0070935 3'-UTR-mediated mRNA stabilization 2/320 24/18722 0.0628021329667426 0.177007150662585 ZFP36/YBX3 2 GO:0071294 cellular response to zinc ion 2/320 24/18722 0.0628021329667426 0.177007150662585 TSPO/PARP1 2 GO:1900373 positive regulation of purine nucleotide biosynthetic process 2/320 24/18722 0.0628021329667426 0.177007150662585 TMSB4X/ENO1 2 GO:1903428 positive regulation of reactive oxygen species biosynthetic process 2/320 24/18722 0.0628021329667426 0.177007150662585 CYBA/SOD2 2 GO:2000209 regulation of anoikis 2/320 24/18722 0.0628021329667426 0.177007150662585 CAV1/ITGB1 2 GO:2000679 positive regulation of transcription regulatory region DNA binding 2/320 24/18722 0.0628021329667426 0.177007150662585 PARP1/CTNNB1 2 GO:2001026 regulation of endothelial cell chemotaxis 2/320 24/18722 0.0628021329667426 0.177007150662585 TMSB4X/HSPB1 2 GO:0060348 bone development 7/320 205/18722 0.0628711884777652 0.177007150662585 PTPRC/TYROBP/FBN1/ANXA6/SNX10/RHOA/GJA1 7 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 6/320 164/18722 0.0628863739527287 0.177007150662585 LAPTM5/CAV1/RPL23/DDA1/HSPA1A/PBK 6 GO:0050808 synapse organization 12/320 426/18722 0.0631830496284408 0.177721144359916 FLNA/SRGN/NRP2/ACTG1/RAB17/CDC42/PFN1/MYH10/TUBB/RHOA/ACTB/CTNNB1 12 GO:0048880 sensory system development 11/320 381/18722 0.0638392718295703 0.179444810339989 VIM/RDH13/FBN1/C12orf57/ISL1/ATP2B1/HMGB1/FLT1/TGFBR1/CLIC4/CTNNB1 11 GO:0001843 neural tube closure 4/320 88/18722 0.0640859878558227 0.179771420108798 LMO4/PFN1/VASP/LRP2 4 GO:0010232 vascular transport 4/320 88/18722 0.0640859878558227 0.179771420108798 SLC2A3/LRP2/GJA1/TFRC 4 GO:0030101 natural killer cell activation 4/320 88/18722 0.0640859878558227 0.179771420108798 PTPRC/TYROBP/CORO1A/HLA-E 4 GO:0001706 endoderm formation 3/320 54/18722 0.0648478899265248 0.181293289023275 ITGB2/FN1/CTNNB1 3 GO:0010524 positive regulation of calcium ion transport into cytosol 3/320 54/18722 0.0648478899265248 0.181293289023275 CAV1/SRI/GSTO1 3 GO:0070228 regulation of lymphocyte apoptotic process 3/320 54/18722 0.0648478899265248 0.181293289023275 TSC22D3/CD74/SLC39A10 3 GO:1902743 regulation of lamellipodium organization 3/320 54/18722 0.0648478899265248 0.181293289023275 CDC42/CAPZB/ACTR3 3 GO:2000179 positive regulation of neural precursor cell proliferation 3/320 54/18722 0.0648478899265248 0.181293289023275 FLNA/LRP2/CTNNB1 3 GO:0007265 Ras protein signal transduction 10/320 337/18722 0.0649385405730232 0.181423968659724 AIF1/EPS8L1/ARHGDIB/TIMP2/CDC42/ITGB1/STMN1/JUN/DHCR24/RHOA 10 GO:0001822 kidney development 9/320 293/18722 0.0653921949695187 0.182567938928413 FBN1/TGFBR1/ADAMTS6/STAT1/MAGED1/LRP2/RHOA/CTNNB1/SOX4 9 GO:0010657 muscle cell apoptotic process 4/320 89/18722 0.0662415188744832 0.184565041125667 SOD2/HMOX1/PPP1R10/PDCD4 4 GO:0014910 regulation of smooth muscle cell migration 4/320 89/18722 0.0662415188744832 0.184565041125667 AIF1/IGFBP3/SEMA6D/RHOA 4 GO:0060606 tube closure 4/320 89/18722 0.0662415188744832 0.184565041125667 LMO4/PFN1/VASP/LRP2 4 GO:0035270 endocrine system development 5/320 127/18722 0.0670436159708903 0.186103748331423 TSPO/ANXA1/ISL1/TGFBR1/SOX4 5 GO:0003094 glomerular filtration 2/320 25/18722 0.0675144043438535 0.186103748331423 CYBA/GJA1 2 GO:0010954 positive regulation of protein processing 2/320 25/18722 0.0675144043438535 0.186103748331423 ENO1/MYH9 2 GO:0016540 protein autoprocessing 2/320 25/18722 0.0675144043438535 0.186103748331423 PARP1/CTSL 2 GO:0032331 negative regulation of chondrocyte differentiation 2/320 25/18722 0.0675144043438535 0.186103748331423 TGFBR1/CTNNB1 2 GO:0033622 integrin activation 2/320 25/18722 0.0675144043438535 0.186103748331423 PLEK/FN1 2 GO:0060706 cell differentiation involved in embryonic placenta development 2/320 25/18722 0.0675144043438535 0.186103748331423 KRT19/KRT8 2 GO:0061436 establishment of skin barrier 2/320 25/18722 0.0675144043438535 0.186103748331423 STMN1/PLEC 2 GO:0071450 cellular response to oxygen radical 2/320 25/18722 0.0675144043438535 0.186103748331423 SOD2/SOD3 2 GO:0071451 cellular response to superoxide 2/320 25/18722 0.0675144043438535 0.186103748331423 SOD2/SOD3 2 GO:0072202 cell differentiation involved in metanephros development 2/320 25/18722 0.0675144043438535 0.186103748331423 STAT1/CTNNB1 2 GO:0090169 regulation of spindle assembly 2/320 25/18722 0.0675144043438535 0.186103748331423 CCSAP/HSPA1A 2 GO:1904385 cellular response to angiotensin 2/320 25/18722 0.0675144043438535 0.186103748331423 CAV1/CYBA 2 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell 2/320 25/18722 0.0675144043438535 0.186103748331423 ITGB2/RHOA 2 GO:1905048 regulation of metallopeptidase activity 2/320 25/18722 0.0675144043438535 0.186103748331423 TIMP2/TIMP3 2 GO:1905564 positive regulation of vascular endothelial cell proliferation 2/320 25/18722 0.0675144043438535 0.186103748331423 IGF2/HMGB1 2 GO:0046879 hormone secretion 9/320 295/18722 0.0676166787224275 0.18626141098738 HLA-DRB1/ANXA1/CYP19A1/DYNLL1/ISL1/SRI/HMGN3/SOX4/GJA1 9 GO:0010676 positive regulation of cellular carbohydrate metabolic process 3/320 55/18722 0.0677570874988769 0.186275639085402 IGF2/PMAIP1/HMGB1 3 GO:0038066 p38MAPK cascade 3/320 55/18722 0.0677570874988769 0.186275639085402 NCF1/EZR/ZFP36 3 GO:0098900 regulation of action potential 3/320 55/18722 0.0677570874988769 0.186275639085402 FLNA/CAV1/DSP 3 GO:0045638 negative regulation of myeloid cell differentiation 4/320 90/18722 0.0684344116344675 0.187762940819136 CCL3/ZFP36/FBN1/CTNNB1 4 GO:0046849 bone remodeling 4/320 90/18722 0.0684344116344675 0.187762940819136 SNX10/CTNNB1/GJA1/TFRC 4 GO:0097581 lamellipodium organization 4/320 90/18722 0.0684344116344675 0.187762940819136 CDC42/ITGB1/CAPZB/ACTR3 4 GO:0016482 cytosolic transport 6/320 168/18722 0.0689480269372675 0.189046614004505 FLNA/CORO1A/LAPTM5/MSN/EZR/VPS13C 6 GO:0031214 biomineral tissue development 6/320 169/18722 0.0705146177033535 0.192513087338716 SRGN/CCL3/ISG15/ATP2B1/SNX10/CEBPB 6 GO:0055006 cardiac cell development 4/320 91/18722 0.070664447304942 0.192513087338716 ISL1/PLEC/CDK1/PDCD4 4 GO:0060191 regulation of lipase activity 4/320 91/18722 0.070664447304942 0.192513087338716 ANXA1/FLT1/PPT1/RHOA 4 GO:0022029 telencephalon cell migration 3/320 56/18722 0.0707247983011061 0.192513087338716 CXCR4/RHOA/CTNNB1 3 GO:0031122 cytoplasmic microtubule organization 3/320 56/18722 0.0707247983011061 0.192513087338716 EZR/DST/RHOA 3 GO:0032608 interferon-beta production 3/320 56/18722 0.0707247983011061 0.192513087338716 ISG15/HMGB1/REL 3 GO:0032648 regulation of interferon-beta production 3/320 56/18722 0.0707247983011061 0.192513087338716 ISG15/HMGB1/REL 3 GO:0046622 positive regulation of organ growth 3/320 56/18722 0.0707247983011061 0.192513087338716 IGF2/CDK1/YBX3 3 GO:0048255 mRNA stabilization 3/320 56/18722 0.0707247983011061 0.192513087338716 ZFP36/FUS/YBX3 3 GO:0051058 negative regulation of small GTPase mediated signal transduction 3/320 56/18722 0.0707247983011061 0.192513087338716 TIMP2/ITGB1/STMN1 3 GO:1904645 response to amyloid-beta 3/320 56/18722 0.0707247983011061 0.192513087338716 NAMPT/PARP1/GJA1 3 GO:0031647 regulation of protein stability 9/320 298/18722 0.0710417150795268 0.19312129388724 GAPDH/FLNA/TYROBP/RPL23/IFI30/PFN1/HSPA1A/PLPP3/SOX4 9 GO:0048511 rhythmic process 9/320 298/18722 0.0710417150795268 0.19312129388724 BHLHE40/JUN/NAMPT/CDK1/BHLHE41/MAGED1/ID1/EZH2/TOP2A 9 GO:0043487 regulation of RNA stability 6/320 170/18722 0.0721016482927351 0.194727658310708 VIM/TNFRSF1B/ZFP36/FUS/ZFP36L2/YBX3 6 GO:0002407 dendritic cell chemotaxis 2/320 26/18722 0.0723395342465967 0.194727658310708 CXCR4/HMGB1 2 GO:0009164 nucleoside catabolic process 2/320 26/18722 0.0723395342465967 0.194727658310708 UPP1/APOBEC3A 2 GO:0014829 vascular associated smooth muscle contraction 2/320 26/18722 0.0723395342465967 0.194727658310708 ATP2B1/RHOA 2 GO:0033598 mammary gland epithelial cell proliferation 2/320 26/18722 0.0723395342465967 0.194727658310708 GPX1/CEBPB 2 GO:0046639 negative regulation of alpha-beta T cell differentiation 2/320 26/18722 0.0723395342465967 0.194727658310708 ANXA1/HMGB1 2 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 2/320 26/18722 0.0723395342465967 0.194727658310708 PTPRC/SLC39A10 2 GO:0060037 pharyngeal system development 2/320 26/18722 0.0723395342465967 0.194727658310708 ISL1/TGFBR1 2 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 2/320 26/18722 0.0723395342465967 0.194727658310708 SRI/GSTO1 2 GO:0060544 regulation of necroptotic process 2/320 26/18722 0.0723395342465967 0.194727658310708 CAV1/YBX3 2 GO:0070977 bone maturation 2/320 26/18722 0.0723395342465967 0.194727658310708 SNX10/RHOA 2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway 2/320 26/18722 0.0723395342465967 0.194727658310708 ARRDC3/PDE4B 2 GO:0072273 metanephric nephron morphogenesis 2/320 26/18722 0.0723395342465967 0.194727658310708 STAT1/CTNNB1 2 GO:0097205 renal filtration 2/320 26/18722 0.0723395342465967 0.194727658310708 CYBA/GJA1 2 GO:1905063 regulation of vascular associated smooth muscle cell differentiation 2/320 26/18722 0.0723395342465967 0.194727658310708 SOD2/PDCD4 2 GO:0043467 regulation of generation of precursor metabolites and energy 5/320 130/18722 0.0725227314852009 0.195093702146387 IGF2/PHLDA2/HMGB1/CDK1/RHOA 5 GO:0001708 cell fate specification 4/320 92/18722 0.0729313938900149 0.19606539983965 LMO4/ISL1/ITGB1/CTNNB1 4 GO:0110148 biomineralization 6/320 171/18722 0.0737090956188925 0.198008870625585 SRGN/CCL3/ISG15/ATP2B1/SNX10/CEBPB 6 GO:0061756 leukocyte adhesion to vascular endothelial cell 3/320 57/18722 0.0737501577668866 0.198008870625585 ITGB2/ITGB1/RHOA 3 GO:0045089 positive regulation of innate immune response 5/320 131/18722 0.0744020718827222 0.199499909811426 MNDA/FCN1/TYROBP/HLA-E/HMGB1 5 GO:0046683 response to organophosphorus 5/320 131/18722 0.0744020718827222 0.199499909811426 LDHA/EZR/JUN/STAT1/RFC3 5 GO:0033273 response to vitamin 4/320 93/18722 0.0752350065829834 0.200963334085203 TSPO/SOD2/STC2/ATP2B1 4 GO:0051591 response to cAMP 4/320 93/18722 0.0752350065829834 0.200963334085203 LDHA/EZR/JUN/STAT1 4 GO:0060993 kidney morphogenesis 4/320 93/18722 0.0752350065829834 0.200963334085203 STAT1/MAGED1/CTNNB1/SOX4 4 GO:1901019 regulation of calcium ion transmembrane transporter activity 4/320 93/18722 0.0752350065829834 0.200963334085203 C4orf3/SRI/PDE4B/GSTO1 4 GO:0000082 G1/S transition of mitotic cell cycle 7/320 214/18722 0.075248695984859 0.200963334085203 AIF1/ANXA1/BACH1/ITGB1/EZH2/DBF4/SOX4 7 GO:0002221 pattern recognition receptor signaling pathway 6/320 172/18722 0.0753369323567231 0.200963334085203 CTSS/FCN1/CAV1/CYBA/HMGB1/HSPA1A 6 GO:0042770 signal transduction in response to DNA damage 6/320 172/18722 0.0753369323567231 0.200963334085203 PMAIP1/PTTG1IP/CD74/PPP1R10/CDK1/SOX4 6 GO:1990138 neuron projection extension 6/320 172/18722 0.0753369323567231 0.200963334085203 CXCR4/FN1/NRP2/ITGB1/SEMA6D/CTNNB1 6 GO:0042593 glucose homeostasis 8/320 258/18722 0.0761942236971058 0.202988093047351 HLA-DRB1/CYBA/DYNLL1/PYGL/SRI/HMGN3/TRA2B/SOX4 8 GO:0045165 cell fate commitment 8/320 258/18722 0.0761942236971058 0.202988093047351 LMO4/ISL1/CDC42/ITGB1/TGFBR1/CTSL/RHOA/CTNNB1 8 GO:0007569 cell aging 5/320 132/18722 0.0763077582294593 0.203159572811937 NEK6/NAMPT/B2M/CDK1/PDCD4 5 GO:0031669 cellular response to nutrient levels 7/320 215/18722 0.076706503031576 0.203768281006714 UPP1/CD68/PMAIP1/ATP2B1/JUN/NAMPT/HMOX1 7 GO:0006826 iron ion transport 3/320 58/18722 0.0768322802053387 0.203768281006714 FTH1/B2M/TFRC 3 GO:0010043 response to zinc ion 3/320 58/18722 0.0768322802053387 0.203768281006714 TSPO/SOD2/PARP1 3 GO:0035904 aorta development 3/320 58/18722 0.0768322802053387 0.203768281006714 ADAMTS6/LRP2/SOX4 3 GO:1902808 positive regulation of cell cycle G1/S phase transition 3/320 58/18722 0.0768322802053387 0.203768281006714 AIF1/ANXA1/EZH2 3 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 3/320 58/18722 0.0768322802053387 0.203768281006714 CAV1/PMAIP1/S100A9 3 GO:0002719 negative regulation of cytokine production involved in immune response 2/320 27/18722 0.0772723159564125 0.203888384119985 BST2/HMOX1 2 GO:0033561 regulation of water loss via skin 2/320 27/18722 0.0772723159564125 0.203888384119985 STMN1/PLEC 2 GO:0036037 CD8-positive, alpha-beta T cell activation 2/320 27/18722 0.0772723159564125 0.203888384119985 HLA-A/HLA-E 2 GO:0042104 positive regulation of activated T cell proliferation 2/320 27/18722 0.0772723159564125 0.203888384119985 IGF2/HMGB1 2 GO:0045830 positive regulation of isotype switching 2/320 27/18722 0.0772723159564125 0.203888384119985 PTPRC/TFRC 2 GO:0060142 regulation of syncytium formation by plasma membrane fusion 2/320 27/18722 0.0772723159564125 0.203888384119985 CD53/TYROBP 2 GO:0098901 regulation of cardiac muscle cell action potential 2/320 27/18722 0.0772723159564125 0.203888384119985 CAV1/DSP 2 GO:1903203 regulation of oxidative stress-induced neuron death 2/320 27/18722 0.0772723159564125 0.203888384119985 PARP1/CTNNB1 2 GO:0033500 carbohydrate homeostasis 8/320 259/18722 0.0775210957103346 0.204035656393153 HLA-DRB1/CYBA/DYNLL1/PYGL/SRI/HMGN3/TRA2B/SOX4 8 GO:0002042 cell migration involved in sprouting angiogenesis 4/320 94/18722 0.0775750281204363 0.204035656393153 ANXA1/ITGB1/HMOX1/RHOA 4 GO:0014020 primary neural tube formation 4/320 94/18722 0.0775750281204363 0.204035656393153 LMO4/PFN1/VASP/LRP2 4 GO:0019080 viral gene expression 4/320 94/18722 0.0775750281204363 0.204035656393153 CCL3/ZFP36/JUN/SSB 4 GO:0061326 renal tubule development 4/320 94/18722 0.0775750281204363 0.204035656393153 STAT1/MAGED1/CTNNB1/LGR5 4 GO:0048639 positive regulation of developmental growth 6/320 174/18722 0.0786536437527024 0.206741002535729 IGF2/CXCR4/FN1/EZR/CDK1/YBX3 6 GO:0051091 positive regulation of DNA-binding transcription factor activity 8/320 260/18722 0.0788617800741798 0.20715630976892 CAV1/MTDH/S100A9/HSPA1A/PLPP3/CARD16/CTNNB1/TFRC 8 GO:0042742 defense response to bacterium 10/320 350/18722 0.0789989192747252 0.207384710573802 PLAC8/HLA-A/LYZ/FCER1G/ISG15/GBP2/CYBA/HLA-E/S100A9/CEBPB 10 GO:0051960 regulation of nervous system development 12/320 443/18722 0.0792594660054988 0.207936580022045 TNFRSF1B/TSPO/CXCR4/FN1/BHLHE40/SEMA6D/B2M/BHLHE41/LRP2/ID1/EZH2/CTNNB1 12 GO:0050764 regulation of phagocytosis 4/320 95/18722 0.0799511891358879 0.208741071191857 PTPRC/FCER1G/CYBA/HMGB1 4 GO:1901379 regulation of potassium ion transmembrane transport 4/320 95/18722 0.0799511891358879 0.208741071191857 FLNA/CAV1/CD63/ITGB1 4 GO:0019369 arachidonic acid metabolic process 3/320 59/18722 0.0799702603331824 0.208741071191857 CYP2J2/GPX1/GPX4 3 GO:0021885 forebrain cell migration 3/320 59/18722 0.0799702603331824 0.208741071191857 CXCR4/RHOA/CTNNB1 3 GO:0033013 tetrapyrrole metabolic process 3/320 59/18722 0.0799702603331824 0.208741071191857 TSPO/BLVRA/HMOX1 3 GO:0035306 positive regulation of dephosphorylation 3/320 59/18722 0.0799702603331824 0.208741071191857 PTPRC/PLEK/SLC39A10 3 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 3/320 59/18722 0.0799702603331824 0.208741071191857 PTPRC/CAV1/PARP14 3 GO:2001258 negative regulation of cation channel activity 3/320 59/18722 0.0799702603331824 0.208741071191857 CAV1/SRI/GSTO1 3 GO:0001508 action potential 5/320 134/18722 0.0801977882434246 0.209070827143111 FLNA/CAV1/DSP/SRI/GJA1 5 GO:0098727 maintenance of cell number 5/320 134/18722 0.0801977882434246 0.209070827143111 LBH/ZFP36L2/EZH2/CTNNB1/SOX4 5 GO:0048771 tissue remodeling 6/320 175/18722 0.0803424428404834 0.20918397846054 FLNA/CAV1/SNX10/CTNNB1/GJA1/TFRC 6 GO:1905475 regulation of protein localization to membrane 6/320 175/18722 0.0803424428404834 0.20918397846054 ITGB2/EZR/ITGB1/TCAF1/GBP1/ACTB 6 GO:0009914 hormone transport 9/320 306/18722 0.080695510469508 0.209970937821163 HLA-DRB1/ANXA1/CYP19A1/DYNLL1/ISL1/SRI/HMGN3/SOX4/GJA1 9 GO:0042445 hormone metabolic process 7/320 218/18722 0.0811787968501508 0.210962760116241 TSPO/CYP11A1/RDH13/CYP19A1/STC2/CTSB/CTSL 7 GO:0050803 regulation of synapse structure or activity 7/320 218/18722 0.0811787968501508 0.210962760116241 SRGN/NRP2/RAB17/CDC42/TUBB/PPT1/RHOA 7 GO:0000303 response to superoxide 2/320 28/18722 0.082307686779534 0.212161797737389 SOD2/SOD3 2 GO:0006972 hyperosmotic response 2/320 28/18722 0.082307686779534 0.212161797737389 EFHD1/YBX3 2 GO:0010464 regulation of mesenchymal cell proliferation 2/320 28/18722 0.082307686779534 0.212161797737389 STAT1/CTNNB1 2 GO:0010818 T cell chemotaxis 2/320 28/18722 0.082307686779534 0.212161797737389 CCL3/PLEC 2 GO:0032607 interferon-alpha production 2/320 28/18722 0.082307686779534 0.212161797737389 HMGB1/STAT1 2 GO:0032647 regulation of interferon-alpha production 2/320 28/18722 0.082307686779534 0.212161797737389 HMGB1/STAT1 2 GO:0038094 Fc-gamma receptor signaling pathway 2/320 28/18722 0.082307686779534 0.212161797737389 PTPRC/FCER1G 2 GO:0045589 regulation of regulatory T cell differentiation 2/320 28/18722 0.082307686779534 0.212161797737389 HLA-DRB1/HLA-DRA 2 GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT 2/320 28/18722 0.082307686779534 0.212161797737389 CAV1/PARP14 2 GO:0086011 membrane repolarization during action potential 2/320 28/18722 0.082307686779534 0.212161797737389 FLNA/CAV1 2 GO:1902624 positive regulation of neutrophil migration 2/320 28/18722 0.082307686779534 0.212161797737389 CD99/CD74 2 GO:1903649 regulation of cytoplasmic transport 2/320 28/18722 0.082307686779534 0.212161797737389 MSN/EZR 2 GO:1903672 positive regulation of sprouting angiogenesis 2/320 28/18722 0.082307686779534 0.212161797737389 PKM/HMGB1 2 GO:0003073 regulation of systemic arterial blood pressure 4/320 96/18722 0.0823632085126363 0.21217255459739 CYBA/SOD2/RHOA/GJA1 4 GO:0002712 regulation of B cell mediated immunity 3/320 60/18722 0.0831631747516161 0.213302444490178 PTPRC/HLA-E/TFRC 3 GO:0002889 regulation of immunoglobulin mediated immune response 3/320 60/18722 0.0831631747516161 0.213302444490178 PTPRC/HLA-E/TFRC 3 GO:0006081 cellular aldehyde metabolic process 3/320 60/18722 0.0831631747516161 0.213302444490178 TPI1/RDH13/IDH1 3 GO:0009620 response to fungus 3/320 60/18722 0.0831631747516161 0.213302444490178 GAPDH/COTL1/S100A9 3 GO:0031663 lipopolysaccharide-mediated signaling pathway 3/320 60/18722 0.0831631747516161 0.213302444490178 CCL3/MTDH/CARD16 3 GO:0060038 cardiac muscle cell proliferation 3/320 60/18722 0.0831631747516161 0.213302444490178 TGFBR1/CDK1/GJA1 3 GO:1903670 regulation of sprouting angiogenesis 3/320 60/18722 0.0831631747516161 0.213302444490178 PKM/KLF2/HMGB1 3 GO:0015711 organic anion transport 10/320 354/18722 0.0836770040831758 0.214487208977471 SLC16A3/SLC2A3/SLC6A8/ANXA1/ITGB1/PSAP/SLC43A2/EMB/LRP2/GJA1 10 GO:0071466 cellular response to xenobiotic stimulus 6/320 177/18722 0.0837807079786622 0.214619891734552 CYP2J2/APOBEC3A/CXCR4/PDE4B/GSTO1/TFRC 6 GO:0043401 steroid hormone mediated signaling pathway 5/320 136/18722 0.0841919929507858 0.215136118947518 LBH/ISL1/PARP1/UBA5/RHOA 5 GO:0045727 positive regulation of translation 5/320 136/18722 0.0841919929507858 0.215136118947518 VIM/PKM/RHOA/YBX3/SOX4 5 GO:0099024 plasma membrane invagination 5/320 136/18722 0.0841919929507858 0.215136118947518 AIF1/ITGB2/CDC42/MYH9/RHOA 5 GO:1900180 regulation of protein localization to nucleus 5/320 136/18722 0.0841919929507858 0.215136118947518 FLNA/PARP1/CDK1/MAGED1/TFRC 5 GO:0044706 multi-multicellular organism process 7/320 220/18722 0.0842425557737375 0.215136118947518 ARHGDIB/FBLN1/PGF/STC2/NAMPT/CTSB/GJA1 7 GO:0032868 response to insulin 8/320 264/18722 0.0843625690817775 0.21517662681846 TNFSF10/IGF2/PKM/ATP2B1/PARP1/STAT1/PTPRA/VPS13C 8 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 8/320 264/18722 0.0843625690817775 0.21517662681846 PTPRC/IGF2/ITGB2/NCF1/CAV1/PARP14/ISL1/CD74 8 GO:0014909 smooth muscle cell migration 4/320 97/18722 0.0848107937355547 0.215787068790217 AIF1/IGFBP3/SEMA6D/RHOA 4 GO:1990868 response to chemokine 4/320 97/18722 0.0848107937355547 0.215787068790217 CCL3L3/CXCR4/CCL3/RHOA 4 GO:1990869 cellular response to chemokine 4/320 97/18722 0.0848107937355547 0.215787068790217 CCL3L3/CXCR4/CCL3/RHOA 4 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 4/320 97/18722 0.0848107937355547 0.215787068790217 GPX1/TGFBR1/HMOX1/HSPA1A 4 GO:0030522 intracellular receptor signaling pathway 8/320 265/18722 0.0857722448314151 0.218032986776764 LBH/KLF2/ISL1/PARP1/UBA5/HSPA1A/RHOA/EZH2 8 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 7/320 221/18722 0.0857990407790459 0.218032986776764 LAPTM5/CAV1/RPL23/GPX1/DDA1/HSPA1A/PBK 7 GO:0010977 negative regulation of neuron projection development 5/320 137/18722 0.0862278728881652 0.218912608511833 VIM/FLNA/SEMA6D/B2M/RHOA 5 GO:0030199 collagen fibril organization 3/320 61/18722 0.0864100833695063 0.218912608511833 P4HA1/COL14A1/TGFBR1 3 GO:0040014 regulation of multicellular organism growth 3/320 61/18722 0.0864100833695063 0.218912608511833 PLAC8/IGF2/EZR 3 GO:0043030 regulation of macrophage activation 3/320 61/18722 0.0864100833695063 0.218912608511833 PTPRC/CCL3/CD74 3 GO:0090342 regulation of cell aging 3/320 61/18722 0.0864100833695063 0.218912608511833 NEK6/NAMPT/B2M 3 GO:0032642 regulation of chemokine production 4/320 98/18722 0.0872936412415389 0.219504905429788 AIF1/HMGB1/CD74/HMOX1 4 GO:0070301 cellular response to hydrogen peroxide 4/320 98/18722 0.0872936412415389 0.219504905429788 KLF2/ANXA1/CDK1/EZH2 4 GO:0000305 response to oxygen radical 2/320 29/18722 0.0874407246702399 0.219504905429788 SOD2/SOD3 2 GO:0002360 T cell lineage commitment 2/320 29/18722 0.0874407246702399 0.219504905429788 CTSL/RHOA 2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus 2/320 29/18722 0.0874407246702399 0.219504905429788 HLA-DRB1/GPX1 2 GO:0003209 cardiac atrium morphogenesis 2/320 29/18722 0.0874407246702399 0.219504905429788 ISL1/SOX4 2 GO:0010592 positive regulation of lamellipodium assembly 2/320 29/18722 0.0874407246702399 0.219504905429788 CDC42/ACTR3 2 GO:0021591 ventricular system development 2/320 29/18722 0.0874407246702399 0.219504905429788 C12orf57/SEMA6D 2 GO:0033028 myeloid cell apoptotic process 2/320 29/18722 0.0874407246702399 0.219504905429788 ANXA1/CTSL 2 GO:0040018 positive regulation of multicellular organism growth 2/320 29/18722 0.0874407246702399 0.219504905429788 IGF2/EZR 2 GO:0062098 regulation of programmed necrotic cell death 2/320 29/18722 0.0874407246702399 0.219504905429788 CAV1/YBX3 2 GO:0090025 regulation of monocyte chemotaxis 2/320 29/18722 0.0874407246702399 0.219504905429788 AIF1/HMGB1 2 GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 2/320 29/18722 0.0874407246702399 0.219504905429788 PTTG1IP/CD74 2 GO:1903902 positive regulation of viral life cycle 2/320 29/18722 0.0874407246702399 0.219504905429788 HLA-DRB1/CD74 2 GO:2000406 positive regulation of T cell migration 2/320 29/18722 0.0874407246702399 0.219504905429788 AIF1/RHOA 2 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 5/320 138/18722 0.0882894380700712 0.221500885309978 LAPTM5/CAV1/ARRDC3/PTTG1IP/PDCD6 5 GO:0048663 neuron fate commitment 3/320 62/18722 0.0897100307744369 0.224637322473865 ISL1/CDC42/TGFBR1 3 GO:0060135 maternal process involved in female pregnancy 3/320 62/18722 0.0897100307744369 0.224637322473865 STC2/CTSB/GJA1 3 GO:0071900 regulation of protein serine/threonine kinase activity 10/320 359/18722 0.0897584229665328 0.224637322473865 IGF2/CAV1/FLT1/MAGED1/RHOA/EZH2/ACTB/DBF4/PDCD4/CKS2 10 GO:0010717 regulation of epithelial to mesenchymal transition 4/320 99/18722 0.0898114367683505 0.224637322473865 ISL1/TGFBR1/EZH2/CTNNB1 4 GO:0032602 chemokine production 4/320 99/18722 0.0898114367683505 0.224637322473865 AIF1/HMGB1/CD74/HMOX1 4 GO:0032984 protein-containing complex disassembly 7/320 224/18722 0.0905665926163199 0.226389086927183 PLEK/RPL23/CCSAP/CAPG/STMN1/CAPZA1/CAPZB 7 GO:0044728 DNA methylation or demethylation 4/320 100/18722 0.0923638557016053 0.228596165276356 APOBEC3A/MBD3/PARP1/EZH2 4 GO:0045807 positive regulation of endocytosis 4/320 100/18722 0.0923638557016053 0.228596165276356 CD63/CDC42/B2M/PPT1 4 GO:0060840 artery development 4/320 100/18722 0.0923638557016053 0.228596165276356 TGFBR1/ADAMTS6/LRP2/SOX4 4 GO:0001503 ossification 11/320 408/18722 0.0924879618131922 0.228596165276356 VCAN/IGF2/SRGN/CCL3/ISG15/TPM4/ATP2B1/SNX10/RHOA/CTNNB1/CEBPB 11 GO:0030177 positive regulation of Wnt signaling pathway 5/320 140/18722 0.0924890870209248 0.228596165276356 ZEB2/CAV1/WLS/SOX4/LGR5 5 GO:0050768 negative regulation of neurogenesis 5/320 140/18722 0.0924890870209248 0.228596165276356 TSPO/SEMA6D/B2M/ID1/CTNNB1 5 GO:0000132 establishment of mitotic spindle orientation 2/320 30/18722 0.0926666449268866 0.228596165276356 ITGB1/GJA1 2 GO:0009264 deoxyribonucleotide catabolic process 2/320 30/18722 0.0926666449268866 0.228596165276356 UPP1/SAMHD1 2 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 2/320 30/18722 0.0926666449268866 0.228596165276356 SRI/GSTO1 2 GO:0019674 NAD metabolic process 2/320 30/18722 0.0926666449268866 0.228596165276356 LDHA/ENO1 2 GO:0034390 smooth muscle cell apoptotic process 2/320 30/18722 0.0926666449268866 0.228596165276356 SOD2/PDCD4 2 GO:0034391 regulation of smooth muscle cell apoptotic process 2/320 30/18722 0.0926666449268866 0.228596165276356 SOD2/PDCD4 2 GO:0043304 regulation of mast cell degranulation 2/320 30/18722 0.0926666449268866 0.228596165276356 HMOX1/STXBP2 2 GO:0044030 regulation of DNA methylation 2/320 30/18722 0.0926666449268866 0.228596165276356 MBD3/PARP1 2 GO:0048147 negative regulation of fibroblast proliferation 2/320 30/18722 0.0926666449268866 0.228596165276356 FTH1/IFI30 2 GO:0048799 animal organ maturation 2/320 30/18722 0.0926666449268866 0.228596165276356 SNX10/RHOA 2 GO:0051125 regulation of actin nucleation 2/320 30/18722 0.0926666449268866 0.228596165276356 GMFG/CORO1A 2 GO:0051491 positive regulation of filopodium assembly 2/320 30/18722 0.0926666449268866 0.228596165276356 CDC42/TGFBR1 2 GO:0061311 cell surface receptor signaling pathway involved in heart development 2/320 30/18722 0.0926666449268866 0.228596165276356 GALNT11/CTNNB1 2 GO:0070168 negative regulation of biomineral tissue development 2/320 30/18722 0.0926666449268866 0.228596165276356 SRGN/CCL3 2 GO:0090314 positive regulation of protein targeting to membrane 2/320 30/18722 0.0926666449268866 0.228596165276356 ITGB2/TCAF1 2 GO:2000648 positive regulation of stem cell proliferation 2/320 30/18722 0.0926666449268866 0.228596165276356 PTPRC/GJA1 2 GO:0009260 ribonucleotide biosynthetic process 6/320 182/18722 0.0927277384377163 0.228610390945492 TMSB4X/ALDOA/UPP1/ENO1/PARP1/PPT1 6 GO:0046902 regulation of mitochondrial membrane permeability 3/320 63/18722 0.093062047553122 0.228888321719941 BNIP3L/PMAIP1/HSPA1A 3 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 3/320 63/18722 0.093062047553122 0.228888321719941 PMAIP1/HSPA1A/CEBPB 3 GO:1902373 negative regulation of mRNA catabolic process 3/320 63/18722 0.093062047553122 0.228888321719941 ZFP36/FUS/YBX3 3 GO:2000242 negative regulation of reproductive process 3/320 63/18722 0.093062047553122 0.228888321719941 ARHGDIB/MYH9/GJA1 3 GO:0008584 male gonad development 5/320 141/18722 0.094626886888917 0.232460342821049 TNFSF10/FLNA/TGFBR1/LRP2/YBX3 5 GO:0030183 B cell differentiation 5/320 141/18722 0.094626886888917 0.232460342821049 PTPRC/TNFSF13B/ITGB1/ZFP36L2/EZH2 5 GO:0050830 defense response to Gram-positive bacterium 4/320 101/18722 0.0949505634196775 0.23311689129537 HLA-A/LYZ/GBP2/HLA-E 4 GO:0006959 humoral immune response 9/320 317/18722 0.0952082315294602 0.233610696365635 PTPRC/GAPDH/HLA-A/FCN1/LYZ/HLA-DRB1/HLA-E/HMGN2/S100A9 9 GO:0098657 import into cell 7/320 227/18722 0.0954805962141823 0.234139954633235 SLC2A3/ITGB1/SLC27A2/SLC43A2/SLC39A10/LRP2/ACTB 7 GO:0006940 regulation of smooth muscle contraction 3/320 64/18722 0.0964651515626515 0.236133889962604 CAV1/ATP2B1/RHOA 3 GO:0048247 lymphocyte chemotaxis 3/320 64/18722 0.0964651515626515 0.236133889962604 CCL3L3/CCL3/PLEC 3 GO:0098930 axonal transport 3/320 64/18722 0.0964651515626515 0.236133889962604 ARMCX3/DST/HSPB1 3 GO:0046546 development of primary male sexual characteristics 5/320 142/18722 0.0967898044233159 0.236648208211326 TNFSF10/FLNA/TGFBR1/LRP2/YBX3 5 GO:0050729 positive regulation of inflammatory response 5/320 142/18722 0.0967898044233159 0.236648208211326 CCL3/HLA-E/S100A9/PDCD4/CEBPB 5 GO:0001516 prostaglandin biosynthetic process 2/320 31/18722 0.0979807969592308 0.236758276628972 ANXA1/CD74 2 GO:0001782 B cell homeostasis 2/320 31/18722 0.0979807969592308 0.236758276628972 TNFSF13B/CD74 2 GO:0002828 regulation of type 2 immune response 2/320 31/18722 0.0979807969592308 0.236758276628972 ANXA1/CD74 2 GO:0033006 regulation of mast cell activation involved in immune response 2/320 31/18722 0.0979807969592308 0.236758276628972 HMOX1/STXBP2 2 GO:0034656 nucleobase-containing small molecule catabolic process 2/320 31/18722 0.0979807969592308 0.236758276628972 UPP1/APOBEC3A 2 GO:0036475 neuron death in response to oxidative stress 2/320 31/18722 0.0979807969592308 0.236758276628972 PARP1/CTNNB1 2 GO:0045066 regulatory T cell differentiation 2/320 31/18722 0.0979807969592308 0.236758276628972 HLA-DRB1/HLA-DRA 2 GO:0046386 deoxyribose phosphate catabolic process 2/320 31/18722 0.0979807969592308 0.236758276628972 UPP1/SAMHD1 2 GO:0046457 prostanoid biosynthetic process 2/320 31/18722 0.0979807969592308 0.236758276628972 ANXA1/CD74 2 GO:0048384 retinoic acid receptor signaling pathway 2/320 31/18722 0.0979807969592308 0.236758276628972 KLF2/EZH2 2 GO:0060055 angiogenesis involved in wound healing 2/320 31/18722 0.0979807969592308 0.236758276628972 CXCR4/GPX1 2 GO:0060390 regulation of SMAD protein signal transduction 2/320 31/18722 0.0979807969592308 0.236758276628972 TGFBR1/PARP1 2 GO:0061099 negative regulation of protein tyrosine kinase activity 2/320 31/18722 0.0979807969592308 0.236758276628972 PTPRC/CAV1 2 GO:0070528 protein kinase C signaling 2/320 31/18722 0.0979807969592308 0.236758276628972 PLEK/MYADM 2 GO:0070633 transepithelial transport 2/320 31/18722 0.0979807969592308 0.236758276628972 ACTG1/ACTB 2 GO:0070723 response to cholesterol 2/320 31/18722 0.0979807969592308 0.236758276628972 CCL3/TGFBR1 2 GO:0090183 regulation of kidney development 2/320 31/18722 0.0979807969592308 0.236758276628972 STAT1/MAGED1 2 GO:0110150 negative regulation of biomineralization 2/320 31/18722 0.0979807969592308 0.236758276628972 SRGN/CCL3 2 GO:1901797 negative regulation of signal transduction by p53 class mediator 2/320 31/18722 0.0979807969592308 0.236758276628972 PTTG1IP/CD74 2 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 2/320 31/18722 0.0979807969592308 0.236758276628972 GPX1/HMOX1 2 GO:0015909 long-chain fatty acid transport 3/320 65/18722 0.0999183491540004 0.240455805884875 PLIN2/ANXA1/SLC27A2 3 GO:0043489 RNA stabilization 3/320 65/18722 0.0999183491540004 0.240455805884875 ZFP36/FUS/YBX3 3 GO:0045453 bone resorption 3/320 65/18722 0.0999183491540004 0.240455805884875 SNX10/CTNNB1/TFRC 3 GO:0048524 positive regulation of viral process 3/320 65/18722 0.0999183491540004 0.240455805884875 HLA-DRB1/CD74/TOP2A 3 GO:0048645 animal organ formation 3/320 65/18722 0.0999183491540004 0.240455805884875 ISL1/LRP2/CTNNB1 3 GO:0070613 regulation of protein processing 3/320 65/18722 0.0999183491540004 0.240455805884875 ENO1/MYH9/CARD16 3 GO:1905330 regulation of morphogenesis of an epithelium 3/320 65/18722 0.0999183491540004 0.240455805884875 MAGED1/CTNNB1/GJA1 3 GO:0002027 regulation of heart rate 4/320 103/18722 0.100225458740614 0.240675008913015 CAV1/DSP/ISL1/SRI 4 GO:0050773 regulation of dendrite development 4/320 103/18722 0.100225458740614 0.240675008913015 RAB17/RHOA/ID1/EZH2 4 GO:0071478 cellular response to radiation 6/320 186/18722 0.100242422637778 0.240675008913015 ADIRF/CYBA/NAMPT/PARP1/PBK/CARD16 6 GO:1902115 regulation of organelle assembly 6/320 186/18722 0.100242422637778 0.240675008913015 LCP1/MSN/EZR/CCSAP/HSPA1A/RHOA 6 GO:0045055 regulated exocytosis 7/320 230/18722 0.10053998535153 0.241249256371964 PLEK/ITGB2/CORO1A/CCL3/MYH9/HMOX1/STXBP2 7 GO:0010324 membrane invagination 5/320 144/18722 0.101190359676632 0.242627000220843 AIF1/ITGB2/CDC42/MYH9/RHOA 5 GO:0023061 signal release 12/320 463/18722 0.101231594477428 0.242627000220843 HLA-DRB1/ANXA1/CYP19A1/WLS/DYNLL1/ISL1/SRI/HMGN3/STXBP2/PPT1/SOX4/GJA1 12 GO:0043010 camera-type eye development 9/320 322/18722 0.102277349924678 0.244766964027976 VIM/RDH13/FBN1/C12orf57/ATP2B1/FLT1/TGFBR1/CLIC4/CTNNB1 9 GO:0006892 post-Golgi vesicle-mediated transport 4/320 104/18722 0.102912930134594 0.244766964027976 LAPTM5/VAMP5/KRT18/VPS13C 4 GO:0014896 muscle hypertrophy 4/320 104/18722 0.102912930134594 0.244766964027976 TNFRSF1B/CYBA/PARP1/EZH2 4 GO:1903076 regulation of protein localization to plasma membrane 4/320 104/18722 0.102912930134594 0.244766964027976 EZR/ITGB1/GBP1/ACTB 4 GO:0003338 metanephros morphogenesis 2/320 32/18722 0.103378661125582 0.244766964027976 STAT1/CTNNB1 2 GO:0010039 response to iron ion 2/320 32/18722 0.103378661125582 0.244766964027976 B2M/HMOX1 2 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter 2/320 32/18722 0.103378661125582 0.244766964027976 EZH2/CTNNB1 2 GO:0042744 hydrogen peroxide catabolic process 2/320 32/18722 0.103378661125582 0.244766964027976 GPX3/GPX1 2 GO:0051497 negative regulation of stress fiber assembly 2/320 32/18722 0.103378661125582 0.244766964027976 PFN1/STMN1 2 GO:0060317 cardiac epithelial to mesenchymal transition 2/320 32/18722 0.103378661125582 0.244766964027976 TGFBR1/PDCD4 2 GO:0061037 negative regulation of cartilage development 2/320 32/18722 0.103378661125582 0.244766964027976 TGFBR1/CTNNB1 2 GO:0071875 adrenergic receptor signaling pathway 2/320 32/18722 0.103378661125582 0.244766964027976 ARRDC3/PDE4B 2 GO:0097345 mitochondrial outer membrane permeabilization 2/320 32/18722 0.103378661125582 0.244766964027976 BNIP3L/HSPA1A 2 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 2/320 32/18722 0.103378661125582 0.244766964027976 PMAIP1/HSPA1A 2 GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 2/320 32/18722 0.103378661125582 0.244766964027976 ANXA1/HMGB1 2 GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 3/320 66/18722 0.103420636349195 0.244766964027976 PTPRC/HMGB1/TFRC 3 GO:0016444 somatic cell DNA recombination 3/320 66/18722 0.103420636349195 0.244766964027976 PTPRC/HMGB1/TFRC 3 GO:0045600 positive regulation of fat cell differentiation 3/320 66/18722 0.103420636349195 0.244766964027976 ADIRF/ZFP36/CEBPB 3 GO:0050766 positive regulation of phagocytosis 3/320 66/18722 0.103420636349195 0.244766964027976 PTPRC/FCER1G/CYBA 3 GO:0051893 regulation of focal adhesion assembly 3/320 66/18722 0.103420636349195 0.244766964027976 ACTG1/PTPRA/RHOA 3 GO:0090109 regulation of cell-substrate junction assembly 3/320 66/18722 0.103420636349195 0.244766964027976 ACTG1/PTPRA/RHOA 3 GO:0051961 negative regulation of nervous system development 5/320 145/18722 0.103427666794009 0.244766964027976 TSPO/SEMA6D/B2M/ID1/CTNNB1 5 GO:0006402 mRNA catabolic process 7/320 232/18722 0.103993061396919 0.245964126898724 VIM/ZFP36/FUS/ZFP36L2/SSB/HSPA1A/YBX3 7 GO:0030308 negative regulation of cell growth 6/320 188/18722 0.104117062861302 0.246116535322025 BST2/ENO1/SEMA6D/HSPA1A/PPT1/GJA1 6 GO:0006401 RNA catabolic process 8/320 278/18722 0.105344481280564 0.248875584134528 VIM/TNFRSF1B/ZFP36/FUS/ZFP36L2/SSB/HSPA1A/YBX3 8 GO:0001654 eye development 10/320 371/18722 0.105411829122099 0.248892387390007 VIM/RDH13/FBN1/C12orf57/ATP2B1/HMGB1/FLT1/TGFBR1/CLIC4/CTNNB1 10 GO:0000041 transition metal ion transport 4/320 105/18722 0.10563325856746 0.248978749865858 FTH1/B2M/SLC39A10/TFRC 4 GO:0062207 regulation of pattern recognition receptor signaling pathway 4/320 105/18722 0.10563325856746 0.248978749865858 CAV1/CYBA/HMGB1/HSPA1A 4 GO:2001022 positive regulation of response to DNA damage stimulus 4/320 105/18722 0.10563325856746 0.248978749865858 FUS/PMAIP1/HMGB1/PARP1 4 GO:0010675 regulation of cellular carbohydrate metabolic process 5/320 146/18722 0.105689430606175 0.248978749865858 PLEK/IGF2/PMAIP1/PHLDA2/HMGB1 5 GO:0009880 embryonic pattern specification 3/320 67/18722 0.106970999973495 0.25099612259539 NRP2/EFNB1/CTNNB1 3 GO:0010517 regulation of phospholipase activity 3/320 67/18722 0.106970999973495 0.25099612259539 ANXA1/FLT1/PPT1 3 GO:0016445 somatic diversification of immunoglobulins 3/320 67/18722 0.106970999973495 0.25099612259539 PTPRC/SAMHD1/TFRC 3 GO:0061077 chaperone-mediated protein folding 3/320 67/18722 0.106970999973495 0.25099612259539 CD74/HSPA1A/HSPB1 3 GO:0061180 mammary gland epithelium development 3/320 67/18722 0.106970999973495 0.25099612259539 LBH/GPX1/CEBPB 3 GO:0072665 protein localization to vacuole 3/320 67/18722 0.106970999973495 0.25099612259539 LAPTM5/GBP1/VPS13C 3 GO:1902117 positive regulation of organelle assembly 3/320 67/18722 0.106970999973495 0.25099612259539 LCP1/MSN/RHOA 3 GO:0006417 regulation of translation 12/320 468/18722 0.107244473644448 0.251494985867683 GAPDH/VIM/PKM/ZFP36/EIF4H/ZFP36L2/EIF1/PA2G4/RHOA/YBX3/HSPB1/SOX4 12 GO:0001889 liver development 5/320 147/18722 0.10797547214023 0.253065598912893 ANXA1/KRT18/HMOX1/EZH2/CEBPB 5 GO:0009755 hormone-mediated signaling pathway 6/320 190/18722 0.108068939292754 0.253141075486201 LBH/ISL1/PARP1/UBA5/RHOA/LGR5 6 GO:0006766 vitamin metabolic process 4/320 106/18722 0.108386064467105 0.25340414319869 SLC2A3/CYP11A1/GSTO1/LRP2 4 GO:0035821 modulation of process of other organism 4/320 106/18722 0.108386064467105 0.25340414319869 SERPINB9/CCL3/JUN/S100A9 4 GO:1905477 positive regulation of protein localization to membrane 4/320 106/18722 0.108386064467105 0.25340414319869 ITGB2/EZR/ITGB1/TCAF1 4 GO:0002431 Fc receptor mediated stimulatory signaling pathway 2/320 33/18722 0.108855845638353 0.25340414319869 PTPRC/FCER1G 2 GO:0003382 epithelial cell morphogenesis 2/320 33/18722 0.108855845638353 0.25340414319869 FLNB/CLIC4 2 GO:0010737 protein kinase A signaling 2/320 33/18722 0.108855845638353 0.25340414319869 LCP1/EZR 2 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 2/320 33/18722 0.108855845638353 0.25340414319869 CDC42/FLT1 2 GO:0045920 negative regulation of exocytosis 2/320 33/18722 0.108855845638353 0.25340414319869 ANXA1/HMOX1 2 GO:0046685 response to arsenic-containing substance 2/320 33/18722 0.108855845638353 0.25340414319869 HMOX1/GSTO1 2 GO:0048333 mesodermal cell differentiation 2/320 33/18722 0.108855845638353 0.25340414319869 ITGB1/GJA1 2 GO:0071353 cellular response to interleukin-4 2/320 33/18722 0.108855845638353 0.25340414319869 CORO1A/PARP14 2 GO:0072594 establishment of protein localization to organelle 11/320 422/18722 0.109988187132626 0.255895939882889 TXNIP/TSPO/FLNA/LAPTM5/CD68/RPL23/BNIP3L/PTTG1IP/PPP1R10/CDK1/VPS13C 11 GO:0010812 negative regulation of cell-substrate adhesion 3/320 68/18722 0.110568418743915 0.256956527699582 FBLN1/GBP1/RHOA 3 GO:0051926 negative regulation of calcium ion transport 3/320 68/18722 0.110568418743915 0.256956527699582 C4orf3/SRI/GSTO1 3 GO:0018108 peptidyl-tyrosine phosphorylation 10/320 375/18722 0.110959499612445 0.257575647414957 PTPRC/IGF2/ITGB2/NCF1/CAV1/PARP14/ISL1/FLT1/CD74/PBK 10 GO:0150063 visual system development 10/320 375/18722 0.110959499612445 0.257575647414957 VIM/RDH13/FBN1/C12orf57/ATP2B1/HMGB1/FLT1/TGFBR1/CLIC4/CTNNB1 10 GO:0000018 regulation of DNA recombination 4/320 107/18722 0.11117096026826 0.257776884303282 PTPRC/FUS/PARP1/TFRC 4 GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 4/320 107/18722 0.11117096026826 0.257776884303282 LAPTM5/CAV1/DDA1/HSPA1A 4 GO:0051592 response to calcium ion 5/320 149/18722 0.112619646309664 0.26073288704927 TXNIP/CAV1/FUS/CLIC4/PDCD6 5 GO:1905039 carboxylic acid transmembrane transport 5/320 149/18722 0.112619646309664 0.26073288704927 SLC16A3/ITGB1/SLC43A2/EMB/LRP2 5 GO:0044772 mitotic cell cycle phase transition 11/320 424/18722 0.112635092783869 0.26073288704927 AIF1/NEK6/ANXA1/BACH1/ITGB1/ZFP36L2/CDK1/EZH2/DBF4/SOX4/CKS2 11 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 6/320 193/18722 0.114139822549351 0.261757586474677 PTPRC/IGF2/NCF1/PARP14/ISL1/CD74 6 GO:0006368 transcription elongation from RNA polymerase II promoter 3/320 69/18722 0.114211864315372 0.261757586474677 CDCA4/EZH2/CTNNB1 3 GO:0034605 cellular response to heat 3/320 69/18722 0.114211864315372 0.261757586474677 HMOX1/HSPA1A/PDCD6 3 GO:0045665 negative regulation of neuron differentiation 3/320 69/18722 0.114211864315372 0.261757586474677 ISL1/B2M/RHOA 3 GO:0050688 regulation of defense response to virus 3/320 69/18722 0.114211864315372 0.261757586474677 FGL2/HTRA1/STAT1 3 GO:0002446 neutrophil mediated immunity 2/320 34/18722 0.114408083536609 0.261757586474677 ITGB2/STXBP2 2 GO:0006356 regulation of transcription by RNA polymerase I 2/320 34/18722 0.114408083536609 0.261757586474677 FLNA/POLR2L 2 GO:0010661 positive regulation of muscle cell apoptotic process 2/320 34/18722 0.114408083536609 0.261757586474677 SOD2/PDCD4 2 GO:0014072 response to isoquinoline alkaloid 2/320 34/18722 0.114408083536609 0.261757586474677 AIF1/CXCR4 2 GO:0043276 anoikis 2/320 34/18722 0.114408083536609 0.261757586474677 CAV1/ITGB1 2 GO:0043278 response to morphine 2/320 34/18722 0.114408083536609 0.261757586474677 AIF1/CXCR4 2 GO:0044319 wound healing, spreading of cells 2/320 34/18722 0.114408083536609 0.261757586474677 FLNA/RHOA 2 GO:0048741 skeletal muscle fiber development 2/320 34/18722 0.114408083536609 0.261757586474677 GPX1/PLEC 2 GO:0050931 pigment cell differentiation 2/320 34/18722 0.114408083536609 0.261757586474677 ZEB2/CD63 2 GO:0051085 chaperone cofactor-dependent protein refolding 2/320 34/18722 0.114408083536609 0.261757586474677 CD74/HSPA1A 2 GO:0086019 cell-cell signaling involved in cardiac conduction 2/320 34/18722 0.114408083536609 0.261757586474677 FLNA/GJA1 2 GO:0090075 relaxation of muscle 2/320 34/18722 0.114408083536609 0.261757586474677 SRI/PDE4B 2 GO:0090505 epiboly involved in wound healing 2/320 34/18722 0.114408083536609 0.261757586474677 FLNA/RHOA 2 GO:0098751 bone cell development 2/320 34/18722 0.114408083536609 0.261757586474677 TYROBP/FBN1 2 GO:1904893 negative regulation of receptor signaling pathway via STAT 2/320 34/18722 0.114408083536609 0.261757586474677 CAV1/PARP14 2 GO:2000758 positive regulation of peptidyl-lysine acetylation 2/320 34/18722 0.114408083536609 0.261757586474677 ISL1/SOX4 2 GO:0061008 hepaticobiliary system development 5/320 150/18722 0.114977395180719 0.262769135446201 ANXA1/KRT18/HMOX1/EZH2/CEBPB 5 GO:1903825 organic acid transmembrane transport 5/320 150/18722 0.114977395180719 0.262769135446201 SLC16A3/ITGB1/SLC43A2/EMB/LRP2 5 GO:0072659 protein localization to plasma membrane 8/320 284/18722 0.115148454100523 0.263014600521482 FLNA/MYADM/EZR/VAMP5/KRT18/ITGB1/GBP1/ACTB 8 GO:0018212 peptidyl-tyrosine modification 10/320 378/18722 0.115227473497942 0.263049679830662 PTPRC/IGF2/ITGB2/NCF1/CAV1/PARP14/ISL1/FLT1/CD74/PBK 10 GO:0003002 regionalization 9/320 331/18722 0.115737147449884 0.264067307157879 NRP2/BHLHE40/WLS/ISL1/TGFBR1/TRA2B/BHLHE41/LRP2/CTNNB1 9 GO:0006821 chloride transport 4/320 109/18722 0.11683543329337 0.266132310015548 TSPO/CLIC3/FXYD3/CLIC4 4 GO:0032410 negative regulation of transporter activity 4/320 109/18722 0.11683543329337 0.266132310015548 CAV1/C4orf3/SRI/GSTO1 4 GO:0043266 regulation of potassium ion transport 4/320 109/18722 0.11683543329337 0.266132310015548 FLNA/CAV1/CD63/ITGB1 4 GO:1990778 protein localization to cell periphery 9/320 333/18722 0.118855119640918 0.270583666311996 FLNA/MYADM/CAV1/EZR/VAMP5/KRT18/ITGB1/GBP1/ACTB 9 GO:1905954 positive regulation of lipid localization 4/320 110/18722 0.119714198326255 0.271021334000289 CAV1/PLIN2/CYP19A1/DBI 4 GO:0021915 neural tube development 5/320 152/18722 0.119763220133525 0.271021334000289 LMO4/PFN1/VASP/LRP2/SOX4 5 GO:0050871 positive regulation of B cell activation 5/320 152/18722 0.119763220133525 0.271021334000289 PTPRC/TNFSF13B/CD74/SLC39A10/TFRC 5 GO:0006471 protein ADP-ribosylation 2/320 35/18722 0.120031229724233 0.271021334000289 PARP14/PARP1 2 GO:0009119 ribonucleoside metabolic process 2/320 35/18722 0.120031229724233 0.271021334000289 UPP1/APOBEC3A 2 GO:0032232 negative regulation of actin filament bundle assembly 2/320 35/18722 0.120031229724233 0.271021334000289 PFN1/STMN1 2 GO:0032814 regulation of natural killer cell activation 2/320 35/18722 0.120031229724233 0.271021334000289 TYROBP/HLA-E 2 GO:0033280 response to vitamin D 2/320 35/18722 0.120031229724233 0.271021334000289 STC2/ATP2B1 2 GO:0040001 establishment of mitotic spindle localization 2/320 35/18722 0.120031229724233 0.271021334000289 ITGB1/GJA1 2 GO:0060236 regulation of mitotic spindle organization 2/320 35/18722 0.120031229724233 0.271021334000289 CCSAP/HSPA1A 2 GO:0086005 ventricular cardiac muscle cell action potential 2/320 35/18722 0.120031229724233 0.271021334000289 CAV1/DSP 2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 2/320 35/18722 0.120031229724233 0.271021334000289 ANXA1/HMOX1 2 GO:0090504 epiboly 2/320 35/18722 0.120031229724233 0.271021334000289 FLNA/RHOA 2 GO:0098801 regulation of renal system process 2/320 35/18722 0.120031229724233 0.271021334000289 CYBA/GJA1 2 GO:1905898 positive regulation of response to endoplasmic reticulum stress 2/320 35/18722 0.120031229724233 0.271021334000289 CAV1/PMAIP1 2 GO:0140014 mitotic nuclear division 8/320 287/18722 0.120229315605457 0.27132033428823 IGF2/FLNA/NEK6/CCSAP/CDC42/MKI67/HSPA1A/RHOA 8 GO:0044843 cell cycle G1/S phase transition 7/320 241/18722 0.120312232711683 0.271359249762377 AIF1/ANXA1/BACH1/ITGB1/EZH2/DBF4/SOX4 7 GO:0000281 mitotic cytokinesis 3/320 71/18722 0.121632693160881 0.273739808355533 STMN1/MYH10/RHOA 3 GO:0050795 regulation of behavior 3/320 71/18722 0.121632693160881 0.273739808355533 CCL3/ARRDC3/GJA1 3 GO:0071230 cellular response to amino acid stimulus 3/320 71/18722 0.121632693160881 0.273739808355533 CYBB/CYBA/CEBPB 3 GO:0150116 regulation of cell-substrate junction organization 3/320 71/18722 0.121632693160881 0.273739808355533 ACTG1/PTPRA/RHOA 3 GO:0007338 single fertilization 5/320 153/18722 0.122190883389766 0.274696806401803 ALDOA/MYH9/CDK1/LY6K/SPESP1 5 GO:0120254 olefinic compound metabolic process 5/320 153/18722 0.122190883389766 0.274696806401803 CYP2J2/CYP11A1/GPX1/RDH13/GPX4 5 GO:0015718 monocarboxylic acid transport 4/320 111/18722 0.122623429509927 0.275369571051639 SLC16A3/SLC6A8/ANXA1/EMB 4 GO:0090288 negative regulation of cellular response to growth factor stimulus 4/320 111/18722 0.122623429509927 0.275369571051639 HTRA1/FBN1/LRP2/PDCD6 4 GO:0016358 dendrite development 7/320 243/18722 0.124108953745398 0.27855415365344 LST1/RAB17/CDC42/ITGB1/RHOA/ID1/EZH2 7 GO:0001707 mesoderm formation 3/320 72/18722 0.125407993281301 0.279140375257945 WLS/ITGB1/GJA1 3 GO:0042246 tissue regeneration 3/320 72/18722 0.125407993281301 0.279140375257945 GPX1/ANXA1/EZH2 3 GO:0055021 regulation of cardiac muscle tissue growth 3/320 72/18722 0.125407993281301 0.279140375257945 TGFBR1/CDK1/GJA1 3 GO:0070227 lymphocyte apoptotic process 3/320 72/18722 0.125407993281301 0.279140375257945 TSC22D3/CD74/SLC39A10 3 GO:1901880 negative regulation of protein depolymerization 3/320 72/18722 0.125407993281301 0.279140375257945 CAPG/CAPZA1/CAPZB 3 GO:0045786 negative regulation of cell cycle 10/320 385/18722 0.125539917440589 0.279140375257945 TIMP2/BTG3/ZFP36L2/PPP1R10/CDK1/EZH2/GMNN/CTNNB1/SOX4/PDCD4 10 GO:0001676 long-chain fatty acid metabolic process 4/320 112/18722 0.125562704112604 0.279140375257945 CYP2J2/GPX1/SLC27A2/GPX4 4 GO:0002526 acute inflammatory response 4/320 112/18722 0.125562704112604 0.279140375257945 SERPINA1/FN1/HLA-E/CEBPB 4 GO:0003203 endocardial cushion morphogenesis 2/320 36/18722 0.125721258072371 0.279140375257945 ISL1/TGFBR1 2 GO:0003230 cardiac atrium development 2/320 36/18722 0.125721258072371 0.279140375257945 ISL1/SOX4 2 GO:0008207 C21-steroid hormone metabolic process 2/320 36/18722 0.125721258072371 0.279140375257945 TSPO/CYP11A1 2 GO:0036314 response to sterol 2/320 36/18722 0.125721258072371 0.279140375257945 CCL3/TGFBR1 2 GO:0042092 type 2 immune response 2/320 36/18722 0.125721258072371 0.279140375257945 ANXA1/CD74 2 GO:0045191 regulation of isotype switching 2/320 36/18722 0.125721258072371 0.279140375257945 PTPRC/TFRC 2 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway 2/320 36/18722 0.125721258072371 0.279140375257945 NCF1/PLAUR 2 GO:0051955 regulation of amino acid transport 2/320 36/18722 0.125721258072371 0.279140375257945 ITGB1/SLC43A2 2 GO:0060338 regulation of type I interferon-mediated signaling pathway 2/320 36/18722 0.125721258072371 0.279140375257945 ISG15/SAMHD1 2 GO:0070670 response to interleukin-4 2/320 36/18722 0.125721258072371 0.279140375257945 CORO1A/PARP14 2 GO:0090313 regulation of protein targeting to membrane 2/320 36/18722 0.125721258072371 0.279140375257945 ITGB2/TCAF1 2 GO:1901658 glycosyl compound catabolic process 2/320 36/18722 0.125721258072371 0.279140375257945 UPP1/APOBEC3A 2 GO:0042391 regulation of membrane potential 11/320 434/18722 0.126413489549423 0.280526605165529 TSPO/FLNA/CAV1/BNIP3L/DSP/SOD2/PMAIP1/SRI/JUN/PARP1/GJA1 11 GO:0045860 positive regulation of protein kinase activity 10/320 386/18722 0.127053188004076 0.281794832438455 PTPRC/IGF2/NCF1/HMGB1/FLT1/MAGED1/RHOA/EZH2/DBF4/CKS2 10 GO:0002637 regulation of immunoglobulin production 3/320 73/18722 0.129225155710832 0.285500856616548 PTPRC/HLA-E/TFRC 3 GO:0009166 nucleotide catabolic process 3/320 73/18722 0.129225155710832 0.285500856616548 UPP1/SAMHD1/PDE4B 3 GO:0045739 positive regulation of DNA repair 3/320 73/18722 0.129225155710832 0.285500856616548 FUS/HMGB1/PARP1 3 GO:0050848 regulation of calcium-mediated signaling 3/320 73/18722 0.129225155710832 0.285500856616548 PLEK/CCL3/GBP1 3 GO:0051145 smooth muscle cell differentiation 3/320 73/18722 0.129225155710832 0.285500856616548 SOD2/CTNNB1/PDCD4 3 GO:0072088 nephron epithelium morphogenesis 3/320 73/18722 0.129225155710832 0.285500856616548 STAT1/MAGED1/CTNNB1 3 GO:0072089 stem cell proliferation 3/320 73/18722 0.129225155710832 0.285500856616548 PTPRC/FBLN1/GJA1 3 GO:0007389 pattern specification process 11/320 436/18722 0.129276888366302 0.285500856616548 NRP2/EFNB1/BHLHE40/WLS/GALNT11/ISL1/TGFBR1/TRA2B/BHLHE41/LRP2/CTNNB1 11 GO:0035051 cardiocyte differentiation 5/320 156/18722 0.129610303868697 0.286084281829837 ISL1/ITGB1/PLEC/CDK1/PDCD4 5 GO:0001990 regulation of systemic arterial blood pressure by hormone 2/320 37/18722 0.131474258584824 0.287100140118873 CYBA/RHOA 2 GO:0006623 protein targeting to vacuole 2/320 37/18722 0.131474258584824 0.287100140118873 LAPTM5/VPS13C 2 GO:0006904 vesicle docking involved in exocytosis 2/320 37/18722 0.131474258584824 0.287100140118873 PLEK/STXBP2 2 GO:0014904 myotube cell development 2/320 37/18722 0.131474258584824 0.287100140118873 GPX1/PLEC 2 GO:0033120 positive regulation of RNA splicing 2/320 37/18722 0.131474258584824 0.287100140118873 TRA2B/HSPA1A 2 GO:0033260 nuclear DNA replication 2/320 37/18722 0.131474258584824 0.287100140118873 GMNN/DBF4 2 GO:0042178 xenobiotic catabolic process 2/320 37/18722 0.131474258584824 0.287100140118873 CYP2J2/GSTO1 2 GO:0042401 cellular biogenic amine biosynthetic process 2/320 37/18722 0.131474258584824 0.287100140118873 OAZ1/AZIN1 2 GO:0048846 axon extension involved in axon guidance 2/320 37/18722 0.131474258584824 0.287100140118873 NRP2/SEMA6D 2 GO:0051294 establishment of spindle orientation 2/320 37/18722 0.131474258584824 0.287100140118873 ITGB1/GJA1 2 GO:0060306 regulation of membrane repolarization 2/320 37/18722 0.131474258584824 0.287100140118873 FLNA/CAV1 2 GO:0060428 lung epithelium development 2/320 37/18722 0.131474258584824 0.287100140118873 KLF2/CDC42 2 GO:0072529 pyrimidine-containing compound catabolic process 2/320 37/18722 0.131474258584824 0.287100140118873 UPP1/APOBEC3A 2 GO:0090218 positive regulation of lipid kinase activity 2/320 37/18722 0.131474258584824 0.287100140118873 CDC42/FLT1 2 GO:1900016 negative regulation of cytokine production involved in inflammatory response 2/320 37/18722 0.131474258584824 0.287100140118873 EZH2/PDCD4 2 GO:1902284 neuron projection extension involved in neuron projection guidance 2/320 37/18722 0.131474258584824 0.287100140118873 NRP2/SEMA6D 2 GO:1902745 positive regulation of lamellipodium organization 2/320 37/18722 0.131474258584824 0.287100140118873 CDC42/ACTR3 2 GO:0019751 polyol metabolic process 4/320 114/18722 0.131529662450394 0.287100140118873 PLEK/TPI1/ISYNA1/PLPP3 4 GO:0021987 cerebral cortex development 4/320 114/18722 0.131529662450394 0.287100140118873 FLNA/TRA2B/RHOA/CTNNB1 4 GO:0022904 respiratory electron transport chain 4/320 114/18722 0.131529662450394 0.287100140118873 PLEC/NDUFB1/CDK1/NDUFB7 4 GO:0046660 female sex differentiation 4/320 114/18722 0.131529662450394 0.287100140118873 CYP19A1/LRP2/IDH1/CEBPB 4 GO:0007040 lysosome organization 3/320 74/18722 0.133083131089224 0.289573195187295 CORO1A/LAPTM5/PPT1 3 GO:0010822 positive regulation of mitochondrion organization 3/320 74/18722 0.133083131089224 0.289573195187295 TNFSF10/PLAUR/PMAIP1 3 GO:0048332 mesoderm morphogenesis 3/320 74/18722 0.133083131089224 0.289573195187295 WLS/ITGB1/GJA1 3 GO:0048844 artery morphogenesis 3/320 74/18722 0.133083131089224 0.289573195187295 TGFBR1/LRP2/SOX4 3 GO:0080171 lytic vacuole organization 3/320 74/18722 0.133083131089224 0.289573195187295 CORO1A/LAPTM5/PPT1 3 GO:0120192 tight junction assembly 3/320 74/18722 0.133083131089224 0.289573195187295 ACTG1/MTDH/GJA1 3 GO:0016051 carbohydrate biosynthetic process 6/320 202/18722 0.133354014363847 0.289857331589383 PLEK/IGF2/TPI1/ISYNA1/PGK1/UGP2 6 GO:0019722 calcium-mediated signaling 6/320 202/18722 0.133354014363847 0.289857331589383 PTPRC/PLEK/CXCR4/CCL3/GBP1/GSTO1 6 GO:0000280 nuclear division 11/320 439/18722 0.133638481440428 0.290322926031466 IGF2/FLNA/NEK6/CCSAP/CDC42/MKI67/HSPA1A/ACTR3/RHOA/TOP2A/CKS2 11 GO:0021537 telencephalon development 7/320 248/18722 0.133864431750184 0.290660973195881 FLNA/CXCR4/C12orf57/TRA2B/RHOA/EZH2/CTNNB1 7 GO:0030278 regulation of ossification 4/320 115/18722 0.134556471425786 0.292010157526967 SRGN/CCL3/ISG15/ATP2B1 4 GO:0043488 regulation of mRNA stability 5/320 158/18722 0.134668046159473 0.292098880173723 VIM/ZFP36/FUS/ZFP36L2/YBX3 5 GO:0032869 cellular response to insulin stimulus 6/320 203/18722 0.135578948409418 0.293920364547593 IGF2/PKM/ATP2B1/PARP1/STAT1/PTPRA 6 GO:0045926 negative regulation of growth 7/320 249/18722 0.135860041265738 0.294375296544325 PLAC8/BST2/ENO1/SEMA6D/HSPA1A/PPT1/GJA1 7 GO:0050890 cognition 8/320 296/18722 0.136171206801115 0.294894877621703 HLA-DRA/C12orf57/ITGB1/JUN/B2M/PPT1/CEBPB/TUSC3 8 GO:0008088 axo-dendritic transport 3/320 75/18722 0.136980868449304 0.295298046783402 ARMCX3/DST/HSPB1 3 GO:0034121 regulation of toll-like receptor signaling pathway 3/320 75/18722 0.136980868449304 0.295298046783402 CAV1/CYBA/HMGB1 3 GO:0045913 positive regulation of carbohydrate metabolic process 3/320 75/18722 0.136980868449304 0.295298046783402 IGF2/PMAIP1/HMGB1 3 GO:0061333 renal tubule morphogenesis 3/320 75/18722 0.136980868449304 0.295298046783402 MAGED1/CTNNB1/LGR5 3 GO:1902369 negative regulation of RNA catabolic process 3/320 75/18722 0.136980868449304 0.295298046783402 ZFP36/FUS/YBX3 3 GO:0006882 cellular zinc ion homeostasis 2/320 38/18722 0.137286434625101 0.295298046783402 SLC39A10/S100A9 2 GO:0009309 amine biosynthetic process 2/320 38/18722 0.137286434625101 0.295298046783402 OAZ1/AZIN1 2 GO:0030279 negative regulation of ossification 2/320 38/18722 0.137286434625101 0.295298046783402 SRGN/CCL3 2 GO:0035886 vascular associated smooth muscle cell differentiation 2/320 38/18722 0.137286434625101 0.295298046783402 SOD2/PDCD4 2 GO:0097242 amyloid-beta clearance 2/320 38/18722 0.137286434625101 0.295298046783402 ITGB2/LRP2 2 GO:1901186 positive regulation of ERBB signaling pathway 2/320 38/18722 0.137286434625101 0.295298046783402 NCF1/PLAUR 2 GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 2/320 38/18722 0.137286434625101 0.295298046783402 BNIP3L/HSPA1A 2 GO:1903580 positive regulation of ATP metabolic process 2/320 38/18722 0.137286434625101 0.295298046783402 TMSB4X/ENO1 2 GO:0021782 glial cell development 4/320 116/18722 0.137611574891754 0.295689561857893 VIM/PLEC/S100A9/SOX4 4 GO:0043200 response to amino acid 4/320 116/18722 0.137611574891754 0.295689561857893 CYBB/CYBA/RHOA/CEBPB 4 GO:1901888 regulation of cell junction assembly 6/320 204/18722 0.137821390005796 0.295986477912655 CAV1/ACTG1/RAB17/PTPRA/RHOA/GJA1 6 GO:0043271 negative regulation of ion transport 5/320 160/18722 0.139812800039921 0.300107267410364 CAV1/C4orf3/SRI/SLC43A2/GSTO1 5 GO:0006305 DNA alkylation 3/320 76/18722 0.140917315999919 0.301694481715889 MBD3/PARP1/EZH2 3 GO:0006306 DNA methylation 3/320 76/18722 0.140917315999919 0.301694481715889 MBD3/PARP1/EZH2 3 GO:0014855 striated muscle cell proliferation 3/320 76/18722 0.140917315999919 0.301694481715889 TGFBR1/CDK1/GJA1 3 GO:0072028 nephron morphogenesis 3/320 76/18722 0.140917315999919 0.301694481715889 STAT1/MAGED1/CTNNB1 3 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 3/320 76/18722 0.140917315999919 0.301694481715889 PMAIP1/PTTG1IP/CD74 3 GO:0017038 protein import 6/320 206/18722 0.142358216867983 0.304621518435271 TXNIP/FLNA/RPL23/PTTG1IP/PPP1R10/CDK1 6 GO:0002701 negative regulation of production of molecular mediator of immune response 2/320 39/18722 0.143154100203855 0.305218133148776 BST2/HMOX1 2 GO:0010463 mesenchymal cell proliferation 2/320 39/18722 0.143154100203855 0.305218133148776 STAT1/CTNNB1 2 GO:0032728 positive regulation of interferon-beta production 2/320 39/18722 0.143154100203855 0.305218133148776 ISG15/HMGB1 2 GO:0045923 positive regulation of fatty acid metabolic process 2/320 39/18722 0.143154100203855 0.305218133148776 ANXA1/CD74 2 GO:0051084 'de novo' posttranslational protein folding 2/320 39/18722 0.143154100203855 0.305218133148776 CD74/HSPA1A 2 GO:0051154 negative regulation of striated muscle cell differentiation 2/320 39/18722 0.143154100203855 0.305218133148776 BHLHE41/EZH2 2 GO:0090224 regulation of spindle organization 2/320 39/18722 0.143154100203855 0.305218133148776 CCSAP/HSPA1A 2 GO:0006413 translational initiation 4/320 118/18722 0.143804859641847 0.306289525793873 RPS17/EIF4H/EIF1/HSPB1 4 GO:0022612 gland morphogenesis 4/320 118/18722 0.143804859641847 0.306289525793873 CAV1/MSN/CDC42/CEBPB 4 GO:0007492 endoderm development 3/320 77/18722 0.144891421875678 0.308127305810758 ITGB2/FN1/CTNNB1 3 GO:0021675 nerve development 3/320 77/18722 0.144891421875678 0.308127305810758 NRP2/ISL1/CTNNB1 3 GO:0032418 lysosome localization 3/320 77/18722 0.144891421875678 0.308127305810758 MYH9/HMOX1/STXBP2 3 GO:0034250 positive regulation of cellular amide metabolic process 5/320 162/18722 0.14504264642793 0.30829023407418 VIM/PKM/RHOA/YBX3/SOX4 5 GO:0006869 lipid transport 10/320 398/18722 0.145977542410666 0.310117843311502 CROT/TSPO/CAV1/PLIN2/ANXA1/CYP19A1/DBI/PSAP/SLC27A2/NPC2 10 GO:0009165 nucleotide biosynthetic process 7/320 254/18722 0.146055564004664 0.310124147208258 TMSB4X/ALDOA/UPP1/ENO1/NAMPT/PARP1/PPT1 7 GO:0010906 regulation of glucose metabolic process 4/320 119/18722 0.146942126795937 0.311846362568471 IGF2/PMAIP1/PHLDA2/HMGB1 4 GO:0034637 cellular carbohydrate biosynthetic process 3/320 78/18722 0.148902134854529 0.313153245911968 IGF2/ISYNA1/UGP2 3 GO:0043297 apical junction assembly 3/320 78/18722 0.148902134854529 0.313153245911968 MTDH/RHOA/GJA1 3 GO:0090049 regulation of cell migration involved in sprouting angiogenesis 3/320 78/18722 0.148902134854529 0.313153245911968 ANXA1/HMOX1/RHOA 3 GO:0007339 binding of sperm to zona pellucida 2/320 40/18722 0.14907367732547 0.313153245911968 ALDOA/LY6K 2 GO:0009394 2'-deoxyribonucleotide metabolic process 2/320 40/18722 0.14907367732547 0.313153245911968 UPP1/SAMHD1 2 GO:0010543 regulation of platelet activation 2/320 40/18722 0.14907367732547 0.313153245911968 PLEK/FCER1G 2 GO:0014037 Schwann cell differentiation 2/320 40/18722 0.14907367732547 0.313153245911968 PLEC/CDK1 2 GO:0030501 positive regulation of bone mineralization 2/320 40/18722 0.14907367732547 0.313153245911968 ISG15/ATP2B1 2 GO:0043001 Golgi to plasma membrane protein transport 2/320 40/18722 0.14907367732547 0.313153245911968 VAMP5/KRT18 2 GO:0045429 positive regulation of nitric oxide biosynthetic process 2/320 40/18722 0.14907367732547 0.313153245911968 AIF1/KLF2 2 GO:0045777 positive regulation of blood pressure 2/320 40/18722 0.14907367732547 0.313153245911968 CYBA/RHOA 2 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 2/320 40/18722 0.14907367732547 0.313153245911968 SRI/GSTO1 2 GO:0055069 zinc ion homeostasis 2/320 40/18722 0.14907367732547 0.313153245911968 SLC39A10/S100A9 2 GO:0060412 ventricular septum morphogenesis 2/320 40/18722 0.14907367732547 0.313153245911968 TGFBR1/SOX4 2 GO:0072210 metanephric nephron development 2/320 40/18722 0.14907367732547 0.313153245911968 STAT1/CTNNB1 2 GO:1901223 negative regulation of NIK/NF-kappaB signaling 2/320 40/18722 0.14907367732547 0.313153245911968 TMSB4X/LITAF 2 GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 2/320 40/18722 0.14907367732547 0.313153245911968 BNIP3L/HSPA1A 2 GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell 2/320 40/18722 0.14907367732547 0.313153245911968 ITGB2/RHOA 2 GO:2000142 regulation of DNA-templated transcription, initiation 2/320 40/18722 0.14907367732547 0.313153245911968 HMGB1/JUN 2 GO:2000781 positive regulation of double-strand break repair 2/320 40/18722 0.14907367732547 0.313153245911968 FUS/PARP1 2 GO:0060070 canonical Wnt signaling pathway 8/320 303/18722 0.149274392512652 0.313415543629206 ZEB2/CAV1/WLS/ISL1/PLPP3/CTNNB1/SOX4/LGR5 8 GO:0006304 DNA modification 4/320 120/18722 0.150105860736317 0.314629732933437 APOBEC3A/MBD3/PARP1/EZH2 4 GO:0048675 axon extension 4/320 120/18722 0.150105860736317 0.314629732933437 FN1/NRP2/ITGB1/SEMA6D 4 GO:0071774 response to fibroblast growth factor 4/320 120/18722 0.150105860736317 0.314629732933437 ZFP36/IER2/ZFP36L2/CTNNB1 4 GO:0034976 response to endoplasmic reticulum stress 7/320 256/18722 0.150233413135932 0.314629732933437 CAV1/PMAIP1/JUN/UBE2J1/UBA5/HSPA1A/CEBPB 7 GO:1901293 nucleoside phosphate biosynthetic process 7/320 256/18722 0.150233413135932 0.314629732933437 TMSB4X/ALDOA/UPP1/ENO1/NAMPT/PARP1/PPT1 7 GO:0006066 alcohol metabolic process 9/320 353/18722 0.152489189630099 0.317399134912317 PLEK/TPI1/CYP11A1/RDH13/ISYNA1/DHCR24/NPC2/PLPP3/IDH1 9 GO:0031346 positive regulation of cell projection organization 9/320 353/18722 0.152489189630099 0.317399134912317 EPS8L1/FLNA/FN1/CDC42/PFN1/TGFBR1/S100A9/ACTR3/EZH2 9 GO:0006446 regulation of translational initiation 3/320 79/18722 0.152948405044138 0.317399134912317 EIF4H/EIF1/HSPB1 3 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 3/320 79/18722 0.152948405044138 0.317399134912317 FLNA/MYADM/CDC42 3 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 3/320 79/18722 0.152948405044138 0.317399134912317 NCF1/FN1/FLT1 3 GO:0060420 regulation of heart growth 3/320 79/18722 0.152948405044138 0.317399134912317 TGFBR1/CDK1/GJA1 3 GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 3/320 79/18722 0.152948405044138 0.317399134912317 GAPDH/HMGN2/S100A9 3 GO:0006310 DNA recombination 8/320 305/18722 0.153127624586481 0.317399134912317 PTPRC/FUS/SAMHD1/HMGB3/HMGB1/PARP1/TOP2A/TFRC 8 GO:0002224 toll-like receptor signaling pathway 4/320 121/18722 0.153295594337269 0.317399134912317 CTSS/CAV1/CYBA/HMGB1 4 GO:0043244 regulation of protein-containing complex disassembly 4/320 121/18722 0.153295594337269 0.317399134912317 PLEK/CAPG/CAPZA1/CAPZB 4 GO:0045931 positive regulation of mitotic cell cycle 4/320 121/18722 0.153295594337269 0.317399134912317 AIF1/ANXA1/PPP1R10/CDK1 4 GO:0030100 regulation of endocytosis 6/320 211/18722 0.153996259771188 0.317399134912317 CAV1/RAB17/CD63/CDC42/B2M/PPT1 6 GO:0050807 regulation of synapse organization 6/320 211/18722 0.153996259771188 0.317399134912317 SRGN/NRP2/RAB17/CDC42/TUBB/RHOA 6 GO:0032733 positive regulation of interleukin-10 production 2/320 41/18722 0.155041693392565 0.317399134912317 ISG15/HMGB1 2 GO:0042307 positive regulation of protein import into nucleus 2/320 41/18722 0.155041693392565 0.317399134912317 FLNA/CDK1 2 GO:0044786 cell cycle DNA replication 2/320 41/18722 0.155041693392565 0.317399134912317 GMNN/DBF4 2 GO:0071634 regulation of transforming growth factor beta production 2/320 41/18722 0.155041693392565 0.317399134912317 TYROBP/FN1 2 GO:1901385 regulation of voltage-gated calcium channel activity 2/320 41/18722 0.155041693392565 0.317399134912317 SRI/PDE4B 2 GO:1902622 regulation of neutrophil migration 2/320 41/18722 0.155041693392565 0.317399134912317 CD99/CD74 2 GO:1904407 positive regulation of nitric oxide metabolic process 2/320 41/18722 0.155041693392565 0.317399134912317 AIF1/KLF2 2 GO:2000008 regulation of protein localization to cell surface 2/320 41/18722 0.155041693392565 0.317399134912317 TYROBP/CTNNB1 2 GO:0061013 regulation of mRNA catabolic process 5/320 166/18722 0.155749656619317 0.317399134912317 VIM/ZFP36/FUS/ZFP36L2/YBX3 5 GO:0006469 negative regulation of protein kinase activity 6/320 212/18722 0.15637335711698 0.317399134912317 PTPRC/CAV1/MLLT1/PLEC/HSPB1/PDCD4 6 GO:0007422 peripheral nervous system development 3/320 80/18722 0.157029184538052 0.317399134912317 ISL1/PLEC/CDK1 3 GO:0009791 post-embryonic development 3/320 80/18722 0.157029184538052 0.317399134912317 FBN1/C12orf57/TGFBR1 3 GO:0032204 regulation of telomere maintenance 3/320 80/18722 0.157029184538052 0.317399134912317 PARP1/PPP1R10/CTNNB1 3 GO:1901264 carbohydrate derivative transport 3/320 80/18722 0.157029184538052 0.317399134912317 PSAP/NPC2/GJA1 3 GO:0001915 negative regulation of T cell mediated cytotoxicity 1/320 10/18722 0.158392307887028 0.317399134912317 PTPRC 1 GO:0002084 protein depalmitoylation 1/320 10/18722 0.158392307887028 0.317399134912317 PPT1 1 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 1/320 10/18722 0.158392307887028 0.317399134912317 FGL2 1 GO:0002524 hypersensitivity 1/320 10/18722 0.158392307887028 0.317399134912317 HLA-E 1 GO:0002887 negative regulation of myeloid leukocyte mediated immunity 1/320 10/18722 0.158392307887028 0.317399134912317 HMOX1 1 GO:0002934 desmosome organization 1/320 10/18722 0.158392307887028 0.317399134912317 DSP 1 GO:0003163 sinoatrial node development 1/320 10/18722 0.158392307887028 0.317399134912317 ISL1 1 GO:0003183 mitral valve morphogenesis 1/320 10/18722 0.158392307887028 0.317399134912317 SOX4 1 GO:0003330 regulation of extracellular matrix constituent secretion 1/320 10/18722 0.158392307887028 0.317399134912317 TNFRSF1B 1 GO:0006222 UMP biosynthetic process 1/320 10/18722 0.158392307887028 0.317399134912317 UPP1 1 GO:0006735 NADH regeneration 1/320 10/18722 0.158392307887028 0.317399134912317 ENO1 1 GO:0009174 pyrimidine ribonucleoside monophosphate biosynthetic process 1/320 10/18722 0.158392307887028 0.317399134912317 UPP1 1 GO:0009750 response to fructose 1/320 10/18722 0.158392307887028 0.317399134912317 KRT18 1 GO:0009950 dorsal/ventral axis specification 1/320 10/18722 0.158392307887028 0.317399134912317 CTNNB1 1 GO:0010728 regulation of hydrogen peroxide biosynthetic process 1/320 10/18722 0.158392307887028 0.317399134912317 SOD2 1 GO:0010944 negative regulation of transcription by competitive promoter binding 1/320 10/18722 0.158392307887028 0.317399134912317 BHLHE41 1 GO:0010968 regulation of microtubule nucleation 1/320 10/18722 0.158392307887028 0.317399134912317 HSPA1A 1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 1/320 10/18722 0.158392307887028 0.317399134912317 P4HA1 1 GO:0021562 vestibulocochlear nerve development 1/320 10/18722 0.158392307887028 0.317399134912317 NRP2 1 GO:0030388 fructose 1,6-bisphosphate metabolic process 1/320 10/18722 0.158392307887028 0.317399134912317 ALDOA 1 GO:0030953 astral microtubule organization 1/320 10/18722 0.158392307887028 0.317399134912317 EZR 1 GO:0031125 rRNA 3'-end processing 1/320 10/18722 0.158392307887028 0.317399134912317 RPS21 1 GO:0031340 positive regulation of vesicle fusion 1/320 10/18722 0.158392307887028 0.317399134912317 ANXA1 1 GO:0032070 regulation of deoxyribonuclease activity 1/320 10/18722 0.158392307887028 0.317399134912317 HMGB1 1 GO:0033572 transferrin transport 1/320 10/18722 0.158392307887028 0.317399134912317 TFRC 1 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway 1/320 10/18722 0.158392307887028 0.317399134912317 NAMPT 1 GO:0034756 regulation of iron ion transport 1/320 10/18722 0.158392307887028 0.317399134912317 B2M 1 GO:0035646 endosome to melanosome transport 1/320 10/18722 0.158392307887028 0.317399134912317 CD63 1 GO:0035747 natural killer cell chemotaxis 1/320 10/18722 0.158392307887028 0.317399134912317 CCL3 1 GO:0040015 negative regulation of multicellular organism growth 1/320 10/18722 0.158392307887028 0.317399134912317 PLAC8 1 GO:0042989 sequestering of actin monomers 1/320 10/18722 0.158392307887028 0.317399134912317 TMSB4X 1 GO:0043485 endosome to pigment granule transport 1/320 10/18722 0.158392307887028 0.317399134912317 CD63 1 GO:0044848 biological phase 1/320 10/18722 0.158392307887028 0.317399134912317 CTNNB1 1 GO:0045625 regulation of T-helper 1 cell differentiation 1/320 10/18722 0.158392307887028 0.317399134912317 ANXA1 1 GO:0045792 negative regulation of cell size 1/320 10/18722 0.158392307887028 0.317399134912317 RHOA 1 GO:0045843 negative regulation of striated muscle tissue development 1/320 10/18722 0.158392307887028 0.317399134912317 YBX3 1 GO:0045898 regulation of RNA polymerase II transcription preinitiation complex assembly 1/320 10/18722 0.158392307887028 0.317399134912317 HMGB1 1 GO:0048262 determination of dorsal/ventral asymmetry 1/320 10/18722 0.158392307887028 0.317399134912317 CTNNB1 1 GO:0048757 pigment granule maturation 1/320 10/18722 0.158392307887028 0.317399134912317 CD63 1 GO:0050861 positive regulation of B cell receptor signaling pathway 1/320 10/18722 0.158392307887028 0.317399134912317 SLC39A10 1 GO:0051351 positive regulation of ligase activity 1/320 10/18722 0.158392307887028 0.317399134912317 TMSB4X 1 GO:0051660 establishment of centrosome localization 1/320 10/18722 0.158392307887028 0.317399134912317 EZR 1 GO:0060068 vagina development 1/320 10/18722 0.158392307887028 0.317399134912317 LRP2 1 GO:0060272 embryonic skeletal joint morphogenesis 1/320 10/18722 0.158392307887028 0.317399134912317 CTNNB1 1 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway 1/320 10/18722 0.158392307887028 0.317399134912317 PTPRC 1 GO:0060439 trachea morphogenesis 1/320 10/18722 0.158392307887028 0.317399134912317 CTNNB1 1 GO:0060736 prostate gland growth 1/320 10/18722 0.158392307887028 0.317399134912317 PSAP 1 GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 1/320 10/18722 0.158392307887028 0.317399134912317 CTNNB1 1 GO:0061299 retina vasculature morphogenesis in camera-type eye 1/320 10/18722 0.158392307887028 0.317399134912317 CLIC4 1 GO:0061621 canonical glycolysis 1/320 10/18722 0.158392307887028 0.317399134912317 ENO1 1 GO:0061718 glucose catabolic process to pyruvate 1/320 10/18722 0.158392307887028 0.317399134912317 ENO1 1 GO:0070383 DNA cytosine deamination 1/320 10/18722 0.158392307887028 0.317399134912317 APOBEC3A 1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum 1/320 10/18722 0.158392307887028 0.317399134912317 UBE2J1 1 GO:0072203 cell proliferation involved in metanephros development 1/320 10/18722 0.158392307887028 0.317399134912317 STAT1 1 GO:0090647 modulation of age-related behavioral decline 1/320 10/18722 0.158392307887028 0.317399134912317 B2M 1 GO:1901524 regulation of mitophagy 1/320 10/18722 0.158392307887028 0.317399134912317 VPS13C 1 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/320 10/18722 0.158392307887028 0.317399134912317 PMAIP1 1 GO:1903867 extraembryonic membrane development 1/320 10/18722 0.158392307887028 0.317399134912317 HTRA1 1 GO:1903980 positive regulation of microglial cell activation 1/320 10/18722 0.158392307887028 0.317399134912317 CCL3 1 GO:1904350 regulation of protein catabolic process in the vacuole 1/320 10/18722 0.158392307887028 0.317399134912317 LRP2 1 GO:1905383 protein localization to presynapse 1/320 10/18722 0.158392307887028 0.317399134912317 HSPB1 1 GO:2000425 regulation of apoptotic cell clearance 1/320 10/18722 0.158392307887028 0.317399134912317 HMGB1 1 GO:0006260 DNA replication 7/320 260/18722 0.158755319744915 0.31797236121473 SAMHD1/CDC42/JUN/CDK1/RFC3/GMNN/DBF4 7 GO:0019692 deoxyribose phosphate metabolic process 2/320 42/18722 0.161054778667233 0.319660382211579 UPP1/SAMHD1 2 GO:0021795 cerebral cortex cell migration 2/320 42/18722 0.161054778667233 0.319660382211579 RHOA/CTNNB1 2 GO:0021879 forebrain neuron differentiation 2/320 42/18722 0.161054778667233 0.319660382211579 NRP2/B2M 2 GO:0032467 positive regulation of cytokinesis 2/320 42/18722 0.161054778667233 0.319660382211579 CDC42/RHOA 2 GO:0032691 negative regulation of interleukin-1 beta production 2/320 42/18722 0.161054778667233 0.319660382211579 SERPINB1/CARD16 2 GO:0033003 regulation of mast cell activation 2/320 42/18722 0.161054778667233 0.319660382211579 HMOX1/STXBP2 2 GO:0033574 response to testosterone 2/320 42/18722 0.161054778667233 0.319660382211579 TSPO/MSN 2 GO:0045687 positive regulation of glial cell differentiation 2/320 42/18722 0.161054778667233 0.319660382211579 TNFRSF1B/CXCR4 2 GO:0046688 response to copper ion 2/320 42/18722 0.161054778667233 0.319660382211579 CDK1/SOD3 2 GO:0051452 intracellular pH reduction 2/320 42/18722 0.161054778667233 0.319660382211579 CLIC4/PPT1 2 GO:0051602 response to electrical stimulus 2/320 42/18722 0.161054778667233 0.319660382211579 AIF1/SOD2 2 GO:2000404 regulation of T cell migration 2/320 42/18722 0.161054778667233 0.319660382211579 AIF1/RHOA 2 GO:0000422 autophagy of mitochondrion 3/320 81/18722 0.16114342804257 0.319660382211579 TSPO/BNIP3L/VPS13C 3 GO:0044773 mitotic DNA damage checkpoint signaling 3/320 81/18722 0.16114342804257 0.319660382211579 PPP1R10/CDK1/SOX4 3 GO:0051817 modulation of process of other organism involved in symbiotic interaction 3/320 81/18722 0.16114342804257 0.319660382211579 SERPINB9/CCL3/JUN 3 GO:0061726 mitochondrion disassembly 3/320 81/18722 0.16114342804257 0.319660382211579 TSPO/BNIP3L/VPS13C 3 GO:0071260 cellular response to mechanical stimulus 3/320 81/18722 0.16114342804257 0.319660382211579 CYBA/PLEC/GJA1 3 GO:1903533 regulation of protein targeting 3/320 81/18722 0.16114342804257 0.319660382211579 ITGB2/BNIP3L/TCAF1 3 GO:2001021 negative regulation of response to DNA damage stimulus 3/320 81/18722 0.16114342804257 0.319660382211579 PTTG1IP/CD74/PPP1R10 3 GO:0099173 postsynapse organization 5/320 168/18722 0.161222709711745 0.319660382211579 SRGN/NRP2/ACTG1/CDC42/ACTB 5 GO:2000241 regulation of reproductive process 5/320 168/18722 0.161222709711745 0.319660382211579 ARHGDIB/PHLDA2/MYH9/CTNNB1/GJA1 5 GO:0010508 positive regulation of autophagy 4/320 124/18722 0.163016070311384 0.323061104329324 MTDH/BNIP3L/HMGB1/HMOX1 4 GO:0009152 purine ribonucleotide biosynthetic process 5/320 169/18722 0.163988200321757 0.324676206866076 TMSB4X/ALDOA/ENO1/PARP1/PPT1 5 GO:0021543 pallium development 5/320 169/18722 0.163988200321757 0.324676206866076 FLNA/TRA2B/RHOA/EZH2/CTNNB1 5 GO:0043242 negative regulation of protein-containing complex disassembly 3/320 82/18722 0.165290093475254 0.326940481684897 CAPG/CAPZA1/CAPZB 3 GO:1905897 regulation of response to endoplasmic reticulum stress 3/320 82/18722 0.165290093475254 0.326940481684897 CAV1/PMAIP1/HSPA1A 3 GO:0055007 cardiac muscle cell differentiation 4/320 125/18722 0.166305064394829 0.328027140508943 ISL1/ITGB1/PLEC/CDK1 4 GO:1904375 regulation of protein localization to cell periphery 4/320 125/18722 0.166305064394829 0.328027140508943 EZR/ITGB1/GBP1/ACTB 4 GO:2000027 regulation of animal organ morphogenesis 4/320 125/18722 0.166305064394829 0.328027140508943 CDC42/MAGED1/RHOA/CTNNB1 4 GO:0007259 receptor signaling pathway via JAK-STAT 5/320 170/18722 0.166772641292334 0.328027140508943 PTPRC/CAV1/PARP14/ISL1/STAT1 5 GO:0006458 'de novo' protein folding 2/320 43/18722 0.167109663787833 0.328027140508943 CD74/HSPA1A 2 GO:0009268 response to pH 2/320 43/18722 0.167109663787833 0.328027140508943 CTSS/GJA1 2 GO:0014002 astrocyte development 2/320 43/18722 0.167109663787833 0.328027140508943 VIM/S100A9 2 GO:0014014 negative regulation of gliogenesis 2/320 43/18722 0.167109663787833 0.328027140508943 TSPO/CTNNB1 2 GO:0031952 regulation of protein autophosphorylation 2/320 43/18722 0.167109663787833 0.328027140508943 PTPRC/CAV1 2 GO:0035794 positive regulation of mitochondrial membrane permeability 2/320 43/18722 0.167109663787833 0.328027140508943 BNIP3L/HSPA1A 2 GO:0045981 positive regulation of nucleotide metabolic process 2/320 43/18722 0.167109663787833 0.328027140508943 TMSB4X/ENO1 2 GO:0046636 negative regulation of alpha-beta T cell activation 2/320 43/18722 0.167109663787833 0.328027140508943 ANXA1/HMGB1 2 GO:0061383 trabecula morphogenesis 2/320 43/18722 0.167109663787833 0.328027140508943 TGFBR1/RHOA 2 GO:0071604 transforming growth factor beta production 2/320 43/18722 0.167109663787833 0.328027140508943 TYROBP/FN1 2 GO:1900544 positive regulation of purine nucleotide metabolic process 2/320 43/18722 0.167109663787833 0.328027140508943 TMSB4X/ENO1 2 GO:1904591 positive regulation of protein import 2/320 43/18722 0.167109663787833 0.328027140508943 FLNA/CDK1 2 GO:0070374 positive regulation of ERK1 and ERK2 cascade 6/320 217/18722 0.168497276376379 0.328435454668048 PTPRC/CCL3L3/HLA-DRB1/CCL3/HMGB1/CD74 6 GO:0050886 endocrine process 3/320 83/18722 0.169468142535937 0.328435454668048 CYBA/RHOA/GJA1 3 GO:1901292 nucleoside phosphate catabolic process 3/320 83/18722 0.169468142535937 0.328435454668048 UPP1/SAMHD1/PDE4B 3 GO:0051048 negative regulation of secretion 5/320 171/18722 0.169575760137919 0.328435454668048 TNFRSF1B/ANXA1/CD74/HMOX1/GJA1 5 GO:1901136 carbohydrate derivative catabolic process 5/320 172/18722 0.172397281927775 0.328435454668048 UPP1/APOBEC3A/SAMHD1/PDE4B/CTSL 5 GO:0001731 formation of translation preinitiation complex 1/320 11/18722 0.172784914849199 0.328435454668048 EIF4H 1 GO:0001765 membrane raft assembly 1/320 11/18722 0.172784914849199 0.328435454668048 CAV1 1 GO:0001787 natural killer cell proliferation 1/320 11/18722 0.172784914849199 0.328435454668048 HLA-E 1 GO:0001867 complement activation, lectin pathway 1/320 11/18722 0.172784914849199 0.328435454668048 FCN1 1 GO:0002357 defense response to tumor cell 1/320 11/18722 0.172784914849199 0.328435454668048 LAPTM5 1 GO:0003174 mitral valve development 1/320 11/18722 0.172784914849199 0.328435454668048 SOX4 1 GO:0006020 inositol metabolic process 1/320 11/18722 0.172784914849199 0.328435454668048 ISYNA1 1 GO:0006971 hypotonic response 1/320 11/18722 0.172784914849199 0.328435454668048 TSPO 1 GO:0007042 lysosomal lumen acidification 1/320 11/18722 0.172784914849199 0.328435454668048 PPT1 1 GO:0009155 purine deoxyribonucleotide catabolic process 1/320 11/18722 0.172784914849199 0.328435454668048 SAMHD1 1 GO:0021561 facial nerve development 1/320 11/18722 0.172784914849199 0.328435454668048 NRP2 1 GO:0021604 cranial nerve structural organization 1/320 11/18722 0.172784914849199 0.328435454668048 NRP2 1 GO:0021610 facial nerve morphogenesis 1/320 11/18722 0.172784914849199 0.328435454668048 NRP2 1 GO:0032276 regulation of gonadotropin secretion 1/320 11/18722 0.172784914849199 0.328435454668048 GJA1 1 GO:0032610 interleukin-1 alpha production 1/320 11/18722 0.172784914849199 0.328435454668048 ISL1 1 GO:0032650 regulation of interleukin-1 alpha production 1/320 11/18722 0.172784914849199 0.328435454668048 ISL1 1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway 1/320 11/18722 0.172784914849199 0.328435454668048 PARP1 1 GO:0033234 negative regulation of protein sumoylation 1/320 11/18722 0.172784914849199 0.328435454668048 CTNNB1 1 GO:0033625 positive regulation of integrin activation 1/320 11/18722 0.172784914849199 0.328435454668048 PLEK 1 GO:0033860 regulation of NAD(P)H oxidase activity 1/320 11/18722 0.172784914849199 0.328435454668048 CYBA 1 GO:0034115 negative regulation of heterotypic cell-cell adhesion 1/320 11/18722 0.172784914849199 0.328435454668048 MYADM 1 GO:0034163 regulation of toll-like receptor 9 signaling pathway 1/320 11/18722 0.172784914849199 0.328435454668048 HMGB1 1 GO:0034650 cortisol metabolic process 1/320 11/18722 0.172784914849199 0.328435454668048 CYP11A1 1 GO:0035457 cellular response to interferon-alpha 1/320 11/18722 0.172784914849199 0.328435454668048 IFIT2 1 GO:0035581 sequestering of extracellular ligand from receptor 1/320 11/18722 0.172784914849199 0.328435454668048 FBN1 1 GO:0042447 hormone catabolic process 1/320 11/18722 0.172784914849199 0.328435454668048 CYP19A1 1 GO:0042789 mRNA transcription by RNA polymerase II 1/320 11/18722 0.172784914849199 0.328435454668048 FLNA 1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress 1/320 11/18722 0.172784914849199 0.328435454668048 HMOX1 1 GO:0044068 modulation by symbiont of host cellular process 1/320 11/18722 0.172784914849199 0.328435454668048 SERPINB9 1 GO:0045628 regulation of T-helper 2 cell differentiation 1/320 11/18722 0.172784914849199 0.328435454668048 ANXA1 1 GO:0045945 positive regulation of transcription by RNA polymerase III 1/320 11/18722 0.172784914849199 0.328435454668048 ICE1 1 GO:0048096 chromatin-mediated maintenance of transcription 1/320 11/18722 0.172784914849199 0.328435454668048 CDCA4 1 GO:0048102 autophagic cell death 1/320 11/18722 0.172784914849199 0.328435454668048 LAPTM5 1 GO:0048635 negative regulation of muscle organ development 1/320 11/18722 0.172784914849199 0.328435454668048 YBX3 1 GO:0048680 positive regulation of axon regeneration 1/320 11/18722 0.172784914849199 0.328435454668048 FLNA 1 GO:0048715 negative regulation of oligodendrocyte differentiation 1/320 11/18722 0.172784914849199 0.328435454668048 CTNNB1 1 GO:0051081 nuclear membrane disassembly 1/320 11/18722 0.172784914849199 0.328435454668048 NEK6 1 GO:0055015 ventricular cardiac muscle cell development 1/320 11/18722 0.172784914849199 0.328435454668048 CDK1 1 GO:0060174 limb bud formation 1/320 11/18722 0.172784914849199 0.328435454668048 SOX4 1 GO:0060379 cardiac muscle cell myoblast differentiation 1/320 11/18722 0.172784914849199 0.328435454668048 ISL1 1 GO:0060767 epithelial cell proliferation involved in prostate gland development 1/320 11/18722 0.172784914849199 0.328435454668048 CTNNB1 1 GO:0061314 Notch signaling involved in heart development 1/320 11/18722 0.172784914849199 0.328435454668048 GALNT11 1 GO:0070314 G1 to G0 transition 1/320 11/18722 0.172784914849199 0.328435454668048 EZH2 1 GO:0070587 regulation of cell-cell adhesion involved in gastrulation 1/320 11/18722 0.172784914849199 0.328435454668048 MYADM 1 GO:0070601 centromeric sister chromatid cohesion 1/320 11/18722 0.172784914849199 0.328435454668048 CTNNB1 1 GO:0071044 histone mRNA catabolic process 1/320 11/18722 0.172784914849199 0.328435454668048 SSB 1 GO:0071888 macrophage apoptotic process 1/320 11/18722 0.172784914849199 0.328435454668048 CTSL 1 GO:0072697 protein localization to cell cortex 1/320 11/18722 0.172784914849199 0.328435454668048 EZR 1 GO:0075522 IRES-dependent viral translational initiation 1/320 11/18722 0.172784914849199 0.328435454668048 SSB 1 GO:0075733 intracellular transport of virus 1/320 11/18722 0.172784914849199 0.328435454668048 BST2 1 GO:0090084 negative regulation of inclusion body assembly 1/320 11/18722 0.172784914849199 0.328435454668048 HSPA1A 1 GO:0090160 Golgi to lysosome transport 1/320 11/18722 0.172784914849199 0.328435454668048 LAPTM5 1 GO:0090649 response to oxygen-glucose deprivation 1/320 11/18722 0.172784914849199 0.328435454668048 NAMPT 1 GO:0099624 atrial cardiac muscle cell membrane repolarization 1/320 11/18722 0.172784914849199 0.328435454668048 FLNA 1 GO:1900426 positive regulation of defense response to bacterium 1/320 11/18722 0.172784914849199 0.328435454668048 CYBA 1 GO:1901862 negative regulation of muscle tissue development 1/320 11/18722 0.172784914849199 0.328435454668048 YBX3 1 GO:1902337 regulation of apoptotic process involved in morphogenesis 1/320 11/18722 0.172784914849199 0.328435454668048 TNFRSF1B 1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 1/320 11/18722 0.172784914849199 0.328435454668048 CEBPB 1 GO:2000644 regulation of receptor catabolic process 1/320 11/18722 0.172784914849199 0.328435454668048 LAPTM5 1 GO:0006911 phagocytosis, engulfment 4/320 127/18722 0.172953416317956 0.328435454668048 AIF1/ITGB2/CDC42/MYH9 4 GO:0005978 glycogen biosynthetic process 2/320 44/18722 0.173203177340194 0.328435454668048 IGF2/UGP2 2 GO:0006775 fat-soluble vitamin metabolic process 2/320 44/18722 0.173203177340194 0.328435454668048 CYP11A1/LRP2 2 GO:0009250 glucan biosynthetic process 2/320 44/18722 0.173203177340194 0.328435454668048 IGF2/UGP2 2 GO:0009262 deoxyribonucleotide metabolic process 2/320 44/18722 0.173203177340194 0.328435454668048 UPP1/SAMHD1 2 GO:0046006 regulation of activated T cell proliferation 2/320 44/18722 0.173203177340194 0.328435454668048 IGF2/HMGB1 2 GO:0048066 developmental pigmentation 2/320 44/18722 0.173203177340194 0.328435454668048 ZEB2/CD63 2 GO:0051150 regulation of smooth muscle cell differentiation 2/320 44/18722 0.173203177340194 0.328435454668048 SOD2/PDCD4 2 GO:0089718 amino acid import across plasma membrane 2/320 44/18722 0.173203177340194 0.328435454668048 ITGB1/SLC43A2 2 GO:0002088 lens development in camera-type eye 3/320 84/18722 0.173676541251134 0.328435454668048 VIM/TGFBR1/CTNNB1 3 GO:0006835 dicarboxylic acid transport 3/320 84/18722 0.173676541251134 0.328435454668048 ITGB1/LRP2/GJA1 3 GO:0010921 regulation of phosphatase activity 3/320 84/18722 0.173676541251134 0.328435454668048 PTPRC/PLEK/SLC39A10 3 GO:0032370 positive regulation of lipid transport 3/320 84/18722 0.173676541251134 0.328435454668048 CAV1/CYP19A1/DBI 3 GO:0032508 DNA duplex unwinding 3/320 84/18722 0.173676541251134 0.328435454668048 ANXA1/RFC3/TOP2A 3 GO:0045445 myoblast differentiation 3/320 84/18722 0.173676541251134 0.328435454668048 ISL1/IGFBP3/PLEC 3 GO:1900542 regulation of purine nucleotide metabolic process 3/320 84/18722 0.173676541251134 0.328435454668048 TMSB4X/ENO1/PARP1 3 GO:0006694 steroid biosynthetic process 5/320 173/18722 0.175236929396695 0.33123467166841 TSPO/CYP11A1/CYP19A1/SLC27A2/DHCR24 5 GO:0001952 regulation of cell-matrix adhesion 4/320 128/18722 0.176311803051372 0.333114023872094 PLEKHA2/ACTG1/PTPRA/RHOA 4 GO:0001656 metanephros development 3/320 85/18722 0.177914260492661 0.335221944530631 FBN1/STAT1/CTNNB1 3 GO:0010507 negative regulation of autophagy 3/320 85/18722 0.177914260492661 0.335221944530631 TSPO/NAMPT/HMOX1 3 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 3/320 85/18722 0.177914260492661 0.335221944530631 CAV1/PARP14/ISL1 3 GO:0044774 mitotic DNA integrity checkpoint signaling 3/320 85/18722 0.177914260492661 0.335221944530631 PPP1R10/CDK1/SOX4 3 GO:0055013 cardiac muscle cell development 3/320 85/18722 0.177914260492661 0.335221944530631 ISL1/PLEC/CDK1 3 GO:2000779 regulation of double-strand break repair 3/320 85/18722 0.177914260492661 0.335221944530631 FUS/DEK/PARP1 3 GO:0003009 skeletal muscle contraction 2/320 45/18722 0.179332243482104 0.336665529335781 C12orf57/GSTO1 2 GO:0003197 endocardial cushion development 2/320 45/18722 0.179332243482104 0.336665529335781 ISL1/TGFBR1 2 GO:0003254 regulation of membrane depolarization 2/320 45/18722 0.179332243482104 0.336665529335781 TSPO/PARP1 2 GO:0031670 cellular response to nutrient 2/320 45/18722 0.179332243482104 0.336665529335781 ATP2B1/HMOX1 2 GO:0035307 positive regulation of protein dephosphorylation 2/320 45/18722 0.179332243482104 0.336665529335781 PTPRC/SLC39A10 2 GO:0051180 vitamin transport 2/320 45/18722 0.179332243482104 0.336665529335781 SLC2A3/LRP2 2 GO:1901985 positive regulation of protein acetylation 2/320 45/18722 0.179332243482104 0.336665529335781 ISL1/SOX4 2 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process 2/320 45/18722 0.179332243482104 0.336665529335781 BNIP3L/HSPA1A 2 GO:0006140 regulation of nucleotide metabolic process 3/320 86/18722 0.182180276471308 0.338922169372752 TMSB4X/ENO1/PARP1 3 GO:0006282 regulation of DNA repair 4/320 130/18722 0.18309455639253 0.338922169372752 FUS/HMGB1/DEK/PARP1 4 GO:0042476 odontogenesis 4/320 130/18722 0.18309455639253 0.338922169372752 HTRA1/SNX10/RHOA/CTNNB1 4 GO:0006195 purine nucleotide catabolic process 2/320 46/18722 0.185493879619976 0.338922169372752 SAMHD1/PDE4B 2 GO:0006383 transcription by RNA polymerase III 2/320 46/18722 0.185493879619976 0.338922169372752 POLR2L/ICE1 2 GO:0007019 microtubule depolymerization 2/320 46/18722 0.185493879619976 0.338922169372752 CCSAP/STMN1 2 GO:0031018 endocrine pancreas development 2/320 46/18722 0.185493879619976 0.338922169372752 ANXA1/SOX4 2 GO:0035094 response to nicotine 2/320 46/18722 0.185493879619976 0.338922169372752 B2M/HMOX1 2 GO:0045851 pH reduction 2/320 46/18722 0.185493879619976 0.338922169372752 CLIC4/PPT1 2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 2/320 46/18722 0.185493879619976 0.338922169372752 AIF1/ANXA1 2 GO:0048041 focal adhesion assembly 3/320 87/18722 0.186473571206347 0.338922169372752 ACTG1/PTPRA/RHOA 3 GO:0150104 transport across blood-brain barrier 3/320 87/18722 0.186473571206347 0.338922169372752 SLC2A3/LRP2/TFRC 3 GO:0019827 stem cell population maintenance 4/320 131/18722 0.186517941731421 0.338922169372752 LBH/ZFP36L2/CTNNB1/SOX4 4 GO:0043405 regulation of MAP kinase activity 5/320 177/18722 0.186771155174387 0.338922169372752 CAV1/FLT1/MAGED1/EZH2/PDCD4 5 GO:0098739 import across plasma membrane 5/320 177/18722 0.186771155174387 0.338922169372752 SLC2A3/ITGB1/SLC43A2/SLC39A10/LRP2 5 GO:0000012 single strand break repair 1/320 12/18722 0.186932145208253 0.338922169372752 PARP1 1 GO:0001976 nervous system process involved in regulation of systemic arterial blood pressure 1/320 12/18722 0.186932145208253 0.338922169372752 SOD2 1 GO:0002328 pro-B cell differentiation 1/320 12/18722 0.186932145208253 0.338922169372752 SOX4 1 GO:0002664 regulation of T cell tolerance induction 1/320 12/18722 0.186932145208253 0.338922169372752 HLA-B 1 GO:0002863 positive regulation of inflammatory response to antigenic stimulus 1/320 12/18722 0.186932145208253 0.338922169372752 HLA-E 1 GO:0003207 cardiac chamber formation 1/320 12/18722 0.186932145208253 0.338922169372752 SOX4 1 GO:0003306 Wnt signaling pathway involved in heart development 1/320 12/18722 0.186932145208253 0.338922169372752 CTNNB1 1 GO:0006216 cytidine catabolic process 1/320 12/18722 0.186932145208253 0.338922169372752 APOBEC3A 1 GO:0006703 estrogen biosynthetic process 1/320 12/18722 0.186932145208253 0.338922169372752 CYP19A1 1 GO:0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process 1/320 12/18722 0.186932145208253 0.338922169372752 UPP1 1 GO:0009886 post-embryonic animal morphogenesis 1/320 12/18722 0.186932145208253 0.338922169372752 FBN1 1 GO:0009972 cytidine deamination 1/320 12/18722 0.186932145208253 0.338922169372752 APOBEC3A 1 GO:0010459 negative regulation of heart rate 1/320 12/18722 0.186932145208253 0.338922169372752 SRI 1 GO:0016554 cytidine to uridine editing 1/320 12/18722 0.186932145208253 0.338922169372752 APOBEC3A 1 GO:0021527 spinal cord association neuron differentiation 1/320 12/18722 0.186932145208253 0.338922169372752 LMO4 1 GO:0021559 trigeminal nerve development 1/320 12/18722 0.186932145208253 0.338922169372752 ISL1 1 GO:0021781 glial cell fate commitment 1/320 12/18722 0.186932145208253 0.338922169372752 CTNNB1 1 GO:0021978 telencephalon regionalization 1/320 12/18722 0.186932145208253 0.338922169372752 TRA2B 1 GO:0030397 membrane disassembly 1/320 12/18722 0.186932145208253 0.338922169372752 NEK6 1 GO:0032536 regulation of cell projection size 1/320 12/18722 0.186932145208253 0.338922169372752 EZR 1 GO:0032736 positive regulation of interleukin-13 production 1/320 12/18722 0.186932145208253 0.338922169372752 HLA-E 1 GO:0032908 regulation of transforming growth factor beta1 production 1/320 12/18722 0.186932145208253 0.338922169372752 TYROBP 1 GO:0033004 negative regulation of mast cell activation 1/320 12/18722 0.186932145208253 0.338922169372752 HMOX1 1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 1/320 12/18722 0.186932145208253 0.338922169372752 CROT 1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway 1/320 12/18722 0.186932145208253 0.338922169372752 HMGB1 1 GO:0035112 genitalia morphogenesis 1/320 12/18722 0.186932145208253 0.338922169372752 CTNNB1 1 GO:0038180 nerve growth factor signaling pathway 1/320 12/18722 0.186932145208253 0.338922169372752 CORO1A 1 GO:0042118 endothelial cell activation 1/320 12/18722 0.186932145208253 0.338922169372752 TGFBR1 1 GO:0043301 negative regulation of leukocyte degranulation 1/320 12/18722 0.186932145208253 0.338922169372752 HMOX1 1 GO:0043471 regulation of cellular carbohydrate catabolic process 1/320 12/18722 0.186932145208253 0.338922169372752 HMGB1 1 GO:0043476 pigment accumulation 1/320 12/18722 0.186932145208253 0.338922169372752 CD63 1 GO:0043482 cellular pigment accumulation 1/320 12/18722 0.186932145208253 0.338922169372752 CD63 1 GO:0045602 negative regulation of endothelial cell differentiation 1/320 12/18722 0.186932145208253 0.338922169372752 ID1 1 GO:0045605 negative regulation of epidermal cell differentiation 1/320 12/18722 0.186932145208253 0.338922169372752 EZH2 1 GO:0045683 negative regulation of epidermis development 1/320 12/18722 0.186932145208253 0.338922169372752 EZH2 1 GO:0046087 cytidine metabolic process 1/320 12/18722 0.186932145208253 0.338922169372752 APOBEC3A 1 GO:0048934 peripheral nervous system neuron differentiation 1/320 12/18722 0.186932145208253 0.338922169372752 ISL1 1 GO:0048935 peripheral nervous system neuron development 1/320 12/18722 0.186932145208253 0.338922169372752 ISL1 1 GO:0051001 negative regulation of nitric-oxide synthase activity 1/320 12/18722 0.186932145208253 0.338922169372752 CAV1 1 GO:0051340 regulation of ligase activity 1/320 12/18722 0.186932145208253 0.338922169372752 TMSB4X 1 GO:0051639 actin filament network formation 1/320 12/18722 0.186932145208253 0.338922169372752 LCP1 1 GO:0060009 Sertoli cell development 1/320 12/18722 0.186932145208253 0.338922169372752 FLNA 1 GO:0060019 radial glial cell differentiation 1/320 12/18722 0.186932145208253 0.338922169372752 RHOA 1 GO:0060788 ectodermal placode formation 1/320 12/18722 0.186932145208253 0.338922169372752 CTNNB1 1 GO:0061620 glycolytic process through glucose-6-phosphate 1/320 12/18722 0.186932145208253 0.338922169372752 ENO1 1 GO:0070213 protein auto-ADP-ribosylation 1/320 12/18722 0.186932145208253 0.338922169372752 PARP1 1 GO:0070572 positive regulation of neuron projection regeneration 1/320 12/18722 0.186932145208253 0.338922169372752 FLNA 1 GO:0070586 cell-cell adhesion involved in gastrulation 1/320 12/18722 0.186932145208253 0.338922169372752 MYADM 1 GO:0071107 response to parathyroid hormone 1/320 12/18722 0.186932145208253 0.338922169372752 GJA1 1 GO:0071472 cellular response to salt stress 1/320 12/18722 0.186932145208253 0.338922169372752 EFHD1 1 GO:0071697 ectodermal placode morphogenesis 1/320 12/18722 0.186932145208253 0.338922169372752 CTNNB1 1 GO:0071872 cellular response to epinephrine stimulus 1/320 12/18722 0.186932145208253 0.338922169372752 PDE4B 1 GO:0072584 caveolin-mediated endocytosis 1/320 12/18722 0.186932145208253 0.338922169372752 CAV1 1 GO:0072683 T cell extravasation 1/320 12/18722 0.186932145208253 0.338922169372752 CD99 1 GO:0090677 reversible differentiation 1/320 12/18722 0.186932145208253 0.338922169372752 SOD2 1 GO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus 1/320 12/18722 0.186932145208253 0.338922169372752 CD68 1 GO:0140289 protein mono-ADP-ribosylation 1/320 12/18722 0.186932145208253 0.338922169372752 PARP14 1 GO:1901894 regulation of ATPase-coupled calcium transmembrane transporter activity 1/320 12/18722 0.186932145208253 0.338922169372752 C4orf3 1 GO:1902563 regulation of neutrophil activation 1/320 12/18722 0.186932145208253 0.338922169372752 ITGB2 1 GO:1904748 regulation of apoptotic process involved in development 1/320 12/18722 0.186932145208253 0.338922169372752 TNFRSF1B 1 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation 1/320 12/18722 0.186932145208253 0.338922169372752 CTNNB1 1 GO:1990034 calcium ion export across plasma membrane 1/320 12/18722 0.186932145208253 0.338922169372752 ATP2B1 1 GO:2000105 positive regulation of DNA-dependent DNA replication 1/320 12/18722 0.186932145208253 0.338922169372752 DBF4 1 GO:0050769 positive regulation of neurogenesis 6/320 225/18722 0.188679935928103 0.341941006690754 TNFRSF1B/TSPO/CXCR4/FN1/LRP2/CTNNB1 6 GO:0006109 regulation of carbohydrate metabolic process 5/320 178/18722 0.189697197986011 0.343633854484085 PLEK/IGF2/PMAIP1/PHLDA2/HMGB1 5 GO:0007260 tyrosine phosphorylation of STAT protein 3/320 88/18722 0.19079313297166 0.344966560179663 CAV1/PARP14/ISL1 3 GO:0050779 RNA destabilization 3/320 88/18722 0.19079313297166 0.344966560179663 TNFRSF1B/ZFP36/ZFP36L2 3 GO:0070098 chemokine-mediated signaling pathway 3/320 88/18722 0.19079313297166 0.344966560179663 CCL3L3/CXCR4/CCL3 3 GO:0009261 ribonucleotide catabolic process 2/320 47/18722 0.191685194136618 0.344966560179663 UPP1/PDE4B 2 GO:0010712 regulation of collagen metabolic process 2/320 47/18722 0.191685194136618 0.344966560179663 VIM/ITGB1 2 GO:0010761 fibroblast migration 2/320 47/18722 0.191685194136618 0.344966560179663 ITGB1/PLEC 2 GO:0014911 positive regulation of smooth muscle cell migration 2/320 47/18722 0.191685194136618 0.344966560179663 AIF1/SEMA6D 2 GO:0031641 regulation of myelination 2/320 47/18722 0.191685194136618 0.344966560179663 TNFRSF1B/CTNNB1 2 GO:0035850 epithelial cell differentiation involved in kidney development 2/320 47/18722 0.191685194136618 0.344966560179663 STAT1/CTNNB1 2 GO:0045601 regulation of endothelial cell differentiation 2/320 47/18722 0.191685194136618 0.344966560179663 ID1/CTNNB1 2 GO:0046677 response to antibiotic 2/320 47/18722 0.191685194136618 0.344966560179663 RPL23/EZH2 2 GO:0050798 activated T cell proliferation 2/320 47/18722 0.191685194136618 0.344966560179663 IGF2/HMGB1 2 GO:0090279 regulation of calcium ion import 2/320 47/18722 0.191685194136618 0.344966560179663 CCL3/CTNNB1 2 GO:0120163 negative regulation of cold-induced thermogenesis 2/320 47/18722 0.191685194136618 0.344966560179663 ARRDC3/ID1 2 GO:1900744 regulation of p38MAPK cascade 2/320 47/18722 0.191685194136618 0.344966560179663 NCF1/EZR 2 GO:0006997 nucleus organization 4/320 133/18722 0.193426267729231 0.347513951491137 NEK6/SYNE1/PLEC/CDK1 4 GO:0046328 regulation of JNK cascade 4/320 133/18722 0.193426267729231 0.347513951491137 NCF1/CDC42/HMGB1/PDCD4 4 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 4/320 133/18722 0.193426267729231 0.347513951491137 LAPTM5/CAV1/DDA1/HSPA1A 4 GO:0007411 axon guidance 6/320 227/18722 0.193867382780477 0.347513951491137 NRP2/EFNB1/ISL1/SEMA6D/EMB/VASP 6 GO:0046330 positive regulation of JNK cascade 3/320 89/18722 0.195137956719236 0.347513951491137 NCF1/CDC42/HMGB1 3 GO:0015698 inorganic anion transport 5/320 180/18722 0.19559825045532 0.347513951491137 TSPO/CLIC3/FXYD3/CLIC4/CEBPB 5 GO:0097485 neuron projection guidance 6/320 228/18722 0.196481340046593 0.347513951491137 NRP2/EFNB1/ISL1/SEMA6D/EMB/VASP 6 GO:0008277 regulation of G protein-coupled receptor signaling pathway 4/320 134/18722 0.196910220944179 0.347513951491137 PLEK/ARRDC3/STMN1/PDE4B 4 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 4/320 134/18722 0.196910220944179 0.347513951491137 CAV1/DDA1/HSPA1A/PBK 4 GO:0042552 myelination 4/320 134/18722 0.196910220944179 0.347513951491137 TNFRSF1B/CXCR4/PLEC/CTNNB1 4 GO:0048568 embryonic organ development 10/320 427/18722 0.197192896316112 0.347513951491137 KRT19/IGF2/KRT8/MBD3/FBN1/PHLDA2/TGFBR1/TRA2B/CTNNB1/CEBPB 10 GO:0010569 regulation of double-strand break repair via homologous recombination 2/320 48/18722 0.197903384169043 0.347513951491137 FUS/PARP1 2 GO:0030261 chromosome condensation 2/320 48/18722 0.197903384169043 0.347513951491137 CDK1/TOP2A 2 GO:0042149 cellular response to glucose starvation 2/320 48/18722 0.197903384169043 0.347513951491137 UPP1/PMAIP1 2 GO:0043303 mast cell degranulation 2/320 48/18722 0.197903384169043 0.347513951491137 HMOX1/STXBP2 2 GO:0120009 intermembrane lipid transfer 2/320 48/18722 0.197903384169043 0.347513951491137 TSPO/NPC2 2 GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 2/320 48/18722 0.197903384169043 0.347513951491137 RPL23/PBK 2 GO:0008361 regulation of cell size 5/320 181/18722 0.198572677453687 0.347513951491137 PLEK/FN1/MSN/SEMA6D/RHOA 5 GO:0097696 receptor signaling pathway via STAT 5/320 181/18722 0.198572677453687 0.347513951491137 PTPRC/CAV1/PARP14/ISL1/STAT1 5 GO:1905952 regulation of lipid localization 5/320 181/18722 0.198572677453687 0.347513951491137 TSPO/CAV1/PLIN2/CYP19A1/DBI 5 GO:0001649 osteoblast differentiation 6/320 229/18722 0.199108530110014 0.347513951491137 VCAN/IGF2/CCL3/TPM4/CTNNB1/CEBPB 6 GO:0045444 fat cell differentiation 6/320 229/18722 0.199108530110014 0.347513951491137 PLAC8/ADIRF/GPX1/ZFP36/ZFP36L2/CEBPB 6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 3/320 90/18722 0.199507044480779 0.347513951491137 CAV1/DDA1/HSPA1A 3 GO:0034644 cellular response to UV 3/320 90/18722 0.199507044480779 0.347513951491137 PARP1/PBK/CARD16 3 GO:0061097 regulation of protein tyrosine kinase activity 3/320 90/18722 0.199507044480779 0.347513951491137 PTPRC/NCF1/CAV1 3 GO:0001682 tRNA 5'-leader removal 1/320 13/18722 0.200838169448411 0.347513951491137 SSB 1 GO:0001768 establishment of T cell polarity 1/320 13/18722 0.200838169448411 0.347513951491137 MYH9 1 GO:0001886 endothelial cell morphogenesis 1/320 13/18722 0.200838169448411 0.347513951491137 CLIC4 1 GO:0002551 mast cell chemotaxis 1/320 13/18722 0.200838169448411 0.347513951491137 PGF 1 GO:0003222 ventricular trabecula myocardium morphogenesis 1/320 13/18722 0.200838169448411 0.347513951491137 TGFBR1 1 GO:0006000 fructose metabolic process 1/320 13/18722 0.200838169448411 0.347513951491137 ALDOA 1 GO:0007183 SMAD protein complex assembly 1/320 13/18722 0.200838169448411 0.347513951491137 PARP1 1 GO:0008298 intracellular mRNA localization 1/320 13/18722 0.200838169448411 0.347513951491137 ZFP36 1 GO:0009143 nucleoside triphosphate catabolic process 1/320 13/18722 0.200838169448411 0.347513951491137 SAMHD1 1 GO:0009437 carnitine metabolic process 1/320 13/18722 0.200838169448411 0.347513951491137 CROT 1 GO:0009650 UV protection 1/320 13/18722 0.200838169448411 0.347513951491137 GPX1 1 GO:0010635 regulation of mitochondrial fusion 1/320 13/18722 0.200838169448411 0.347513951491137 TFRC 1 GO:0010755 regulation of plasminogen activation 1/320 13/18722 0.200838169448411 0.347513951491137 ENO1 1 GO:0014029 neural crest formation 1/320 13/18722 0.200838169448411 0.347513951491137 PDCD6 1 GO:0021514 ventral spinal cord interneuron differentiation 1/320 13/18722 0.200838169448411 0.347513951491137 LMO4 1 GO:0021819 layer formation in cerebral cortex 1/320 13/18722 0.200838169448411 0.347513951491137 CTNNB1 1 GO:0030836 positive regulation of actin filament depolymerization 1/320 13/18722 0.200838169448411 0.347513951491137 PLEK 1 GO:0031272 regulation of pseudopodium assembly 1/320 13/18722 0.200838169448411 0.347513951491137 CDC42 1 GO:0031274 positive regulation of pseudopodium assembly 1/320 13/18722 0.200838169448411 0.347513951491137 CDC42 1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 1/320 13/18722 0.200838169448411 0.347513951491137 CARD16 1 GO:0032042 mitochondrial DNA metabolic process 1/320 13/18722 0.200838169448411 0.347513951491137 PARP1 1 GO:0032530 regulation of microvillus organization 1/320 13/18722 0.200838169448411 0.347513951491137 EZR 1 GO:0032905 transforming growth factor beta1 production 1/320 13/18722 0.200838169448411 0.347513951491137 TYROBP 1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter 1/320 13/18722 0.200838169448411 0.347513951491137 CTNNB1 1 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway 1/320 13/18722 0.200838169448411 0.347513951491137 PARP1 1 GO:0033262 regulation of nuclear cell cycle DNA replication 1/320 13/18722 0.200838169448411 0.347513951491137 DBF4 1 GO:0034112 positive regulation of homotypic cell-cell adhesion 1/320 13/18722 0.200838169448411 0.347513951491137 PLAUR 1 GO:0036462 TRAIL-activated apoptotic signaling pathway 1/320 13/18722 0.200838169448411 0.347513951491137 TIMP3 1 GO:0042538 hyperosmotic salinity response 1/320 13/18722 0.200838169448411 0.347513951491137 EFHD1 1 GO:0042659 regulation of cell fate specification 1/320 13/18722 0.200838169448411 0.347513951491137 LMO4 1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity 1/320 13/18722 0.200838169448411 0.347513951491137 NCF1 1 GO:0048012 hepatocyte growth factor receptor signaling pathway 1/320 13/18722 0.200838169448411 0.347513951491137 STMN1 1 GO:0048070 regulation of developmental pigmentation 1/320 13/18722 0.200838169448411 0.347513951491137 ZEB2 1 GO:0048207 vesicle targeting, rough ER to cis-Golgi 1/320 13/18722 0.200838169448411 0.347513951491137 PDCD6 1 GO:0048208 COPII vesicle coating 1/320 13/18722 0.200838169448411 0.347513951491137 PDCD6 1 GO:0048266 behavioral response to pain 1/320 13/18722 0.200838169448411 0.347513951491137 TSPO 1 GO:0048302 regulation of isotype switching to IgG isotypes 1/320 13/18722 0.200838169448411 0.347513951491137 PTPRC 1 GO:0048820 hair follicle maturation 1/320 13/18722 0.200838169448411 0.347513951491137 CTNNB1 1 GO:0051451 myoblast migration 1/320 13/18722 0.200838169448411 0.347513951491137 ANXA1 1 GO:0051481 negative regulation of cytosolic calcium ion concentration 1/320 13/18722 0.200838169448411 0.347513951491137 ATP2B1 1 GO:0051709 regulation of killing of cells of other organism 1/320 13/18722 0.200838169448411 0.347513951491137 SERPINB9 1 GO:0051956 negative regulation of amino acid transport 1/320 13/18722 0.200838169448411 0.347513951491137 SLC43A2 1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore 1/320 13/18722 0.200838169448411 0.347513951491137 CDC42 1 GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1/320 13/18722 0.200838169448411 0.347513951491137 ZFP36 1 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 1/320 13/18722 0.200838169448411 0.347513951491137 BACH1 1 GO:0061615 glycolytic process through fructose-6-phosphate 1/320 13/18722 0.200838169448411 0.347513951491137 ENO1 1 GO:0061744 motor behavior 1/320 13/18722 0.200838169448411 0.347513951491137 C12orf57 1 GO:0070254 mucus secretion 1/320 13/18722 0.200838169448411 0.347513951491137 CYBA 1 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway 1/320 13/18722 0.200838169448411 0.347513951491137 HSPA1A 1 GO:0071696 ectodermal placode development 1/320 13/18722 0.200838169448411 0.347513951491137 CTNNB1 1 GO:0072672 neutrophil extravasation 1/320 13/18722 0.200838169448411 0.347513951491137 CD99 1 GO:0090042 tubulin deacetylation 1/320 13/18722 0.200838169448411 0.347513951491137 FLNA 1 GO:0098814 spontaneous synaptic transmission 1/320 13/18722 0.200838169448411 0.347513951491137 ITGB1 1 GO:0098840 protein transport along microtubule 1/320 13/18722 0.200838169448411 0.347513951491137 HSPB1 1 GO:0099118 microtubule-based protein transport 1/320 13/18722 0.200838169448411 0.347513951491137 HSPB1 1 GO:0120305 regulation of pigmentation 1/320 13/18722 0.200838169448411 0.347513951491137 ZEB2 1 GO:1900115 extracellular regulation of signal transduction 1/320 13/18722 0.200838169448411 0.347513951491137 FBN1 1 GO:1900116 extracellular negative regulation of signal transduction 1/320 13/18722 0.200838169448411 0.347513951491137 FBN1 1 GO:1900121 negative regulation of receptor binding 1/320 13/18722 0.200838169448411 0.347513951491137 B2M 1 GO:1900272 negative regulation of long-term synaptic potentiation 1/320 13/18722 0.200838169448411 0.347513951491137 TYROBP 1 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance 1/320 13/18722 0.200838169448411 0.347513951491137 NRP2 1 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding 1/320 13/18722 0.200838169448411 0.347513951491137 TMSB4X 1 GO:1903054 negative regulation of extracellular matrix organization 1/320 13/18722 0.200838169448411 0.347513951491137 TNFRSF1B 1 GO:1903977 positive regulation of glial cell migration 1/320 13/18722 0.200838169448411 0.347513951491137 CCL3 1 GO:1904925 positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization 1/320 13/18722 0.200838169448411 0.347513951491137 VPS13C 1 GO:1905064 negative regulation of vascular associated smooth muscle cell differentiation 1/320 13/18722 0.200838169448411 0.347513951491137 PDCD4 1 GO:2001023 regulation of response to drug 1/320 13/18722 0.200838169448411 0.347513951491137 ADIRF 1 GO:0045333 cellular respiration 6/320 230/18722 0.201748758987473 0.348943437478543 PLEC/NDUFB1/CDK1/NDUFB7/RHOA/IDH1 6 GO:0006354 DNA-templated transcription, elongation 3/320 91/18722 0.203899405748138 0.350303226974484 CDCA4/EZH2/CTNNB1 3 GO:0072080 nephron tubule development 3/320 91/18722 0.203899405748138 0.350303226974484 STAT1/MAGED1/CTNNB1 3 GO:0007272 ensheathment of neurons 4/320 136/18722 0.203935235090444 0.350303226974484 TNFRSF1B/CXCR4/PLEC/CTNNB1 4 GO:0008366 axon ensheathment 4/320 136/18722 0.203935235090444 0.350303226974484 TNFRSF1B/CXCR4/PLEC/CTNNB1 4 GO:0002204 somatic recombination of immunoglobulin genes involved in immune response 2/320 49/18722 0.204145733435275 0.350303226974484 PTPRC/TFRC 2 GO:0002208 somatic diversification of immunoglobulins involved in immune response 2/320 49/18722 0.204145733435275 0.350303226974484 PTPRC/TFRC 2 GO:0002279 mast cell activation involved in immune response 2/320 49/18722 0.204145733435275 0.350303226974484 HMOX1/STXBP2 2 GO:0006692 prostanoid metabolic process 2/320 49/18722 0.204145733435275 0.350303226974484 ANXA1/CD74 2 GO:0006693 prostaglandin metabolic process 2/320 49/18722 0.204145733435275 0.350303226974484 ANXA1/CD74 2 GO:0008038 neuron recognition 2/320 49/18722 0.204145733435275 0.350303226974484 CXCR4/EMB 2 GO:0009994 oocyte differentiation 2/320 49/18722 0.204145733435275 0.350303226974484 CTNNB1/LGR5 2 GO:0018198 peptidyl-cysteine modification 2/320 49/18722 0.204145733435275 0.350303226974484 GAPDH/S100A9 2 GO:0032692 negative regulation of interleukin-1 production 2/320 49/18722 0.204145733435275 0.350303226974484 SERPINB1/CARD16 2 GO:0042304 regulation of fatty acid biosynthetic process 2/320 49/18722 0.204145733435275 0.350303226974484 ANXA1/CD74 2 GO:0045190 isotype switching 2/320 49/18722 0.204145733435275 0.350303226974484 PTPRC/TFRC 2 GO:0045778 positive regulation of ossification 2/320 49/18722 0.204145733435275 0.350303226974484 ISG15/ATP2B1 2 GO:0072666 establishment of protein localization to vacuole 2/320 49/18722 0.204145733435275 0.350303226974484 LAPTM5/VPS13C 2 GO:0086009 membrane repolarization 2/320 49/18722 0.204145733435275 0.350303226974484 FLNA/CAV1 2 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 2/320 49/18722 0.204145733435275 0.350303226974484 JUN/GJA1 2 GO:0030879 mammary gland development 4/320 137/18722 0.207475306134122 0.355573606365073 CAV1/LBH/GPX1/CEBPB 4 GO:0034754 cellular hormone metabolic process 4/320 137/18722 0.207475306134122 0.355573606365073 TSPO/CYP11A1/RDH13/CYP19A1 4 GO:0045471 response to ethanol 4/320 137/18722 0.207475306134122 0.355573606365073 CYBB/SOD2/CDK1/RHOA 4 GO:1903312 negative regulation of mRNA metabolic process 3/320 92/18722 0.208314057833243 0.356533903900682 ZFP36/FUS/YBX3 3 GO:0030490 maturation of SSU-rRNA 2/320 50/18722 0.210409610109153 0.356533903900682 RPS21/RPS28 2 GO:0038093 Fc receptor signaling pathway 2/320 50/18722 0.210409610109153 0.356533903900682 PTPRC/FCER1G 2 GO:0043628 ncRNA 3'-end processing 2/320 50/18722 0.210409610109153 0.356533903900682 RPS21/SSB 2 GO:0045814 negative regulation of gene expression, epigenetic 2/320 50/18722 0.210409610109153 0.356533903900682 MBD3/EZH2 2 GO:0050873 brown fat cell differentiation 2/320 50/18722 0.210409610109153 0.356533903900682 PLAC8/CEBPB 2 GO:0060425 lung morphogenesis 2/320 50/18722 0.210409610109153 0.356533903900682 CDC42/CTNNB1 2 GO:0060688 regulation of morphogenesis of a branching structure 2/320 50/18722 0.210409610109153 0.356533903900682 MAGED1/CTNNB1 2 GO:0048588 developmental cell growth 6/320 234/18722 0.212436139913976 0.356533903900682 CXCR4/FN1/NRP2/ITGB1/SEMA6D/CTNNB1 6 GO:0060560 developmental growth involved in morphogenesis 6/320 234/18722 0.212436139913976 0.356533903900682 CXCR4/FN1/NRP2/ITGB1/SEMA6D/CTNNB1 6 GO:0019217 regulation of fatty acid metabolic process 3/320 93/18722 0.212750026208251 0.356533903900682 CAV1/ANXA1/CD74 3 GO:0090398 cellular senescence 3/320 93/18722 0.212750026208251 0.356533903900682 NEK6/NAMPT/B2M 3 GO:1901992 positive regulation of mitotic cell cycle phase transition 3/320 93/18722 0.212750026208251 0.356533903900682 AIF1/ANXA1/CDK1 3 GO:0015850 organic hydroxy compound transport 7/320 284/18722 0.214140869865617 0.356533903900682 SLC16A3/TSPO/CAV1/CYP19A1/EMB/NPC2/ACTB 7 GO:0000212 meiotic spindle organization 1/320 14/18722 0.214507087390391 0.356533903900682 MYH9 1 GO:0001711 endodermal cell fate commitment 1/320 14/18722 0.214507087390391 0.356533903900682 CTNNB1 1 GO:0001767 establishment of lymphocyte polarity 1/320 14/18722 0.214507087390391 0.356533903900682 MYH9 1 GO:0001771 immunological synapse formation 1/320 14/18722 0.214507087390391 0.356533903900682 MSN 1 GO:0002467 germinal center formation 1/320 14/18722 0.214507087390391 0.356533903900682 TNFSF13B 1 GO:0002517 T cell tolerance induction 1/320 14/18722 0.214507087390391 0.356533903900682 HLA-B 1 GO:0002829 negative regulation of type 2 immune response 1/320 14/18722 0.214507087390391 0.356533903900682 ANXA1 1 GO:0002864 regulation of acute inflammatory response to antigenic stimulus 1/320 14/18722 0.214507087390391 0.356533903900682 HLA-E 1 GO:0003376 sphingosine-1-phosphate receptor signaling pathway 1/320 14/18722 0.214507087390391 0.356533903900682 EZR 1 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis 1/320 14/18722 0.214507087390391 0.356533903900682 ANXA6 1 GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process 1/320 14/18722 0.214507087390391 0.356533903900682 UPP1 1 GO:0009158 ribonucleoside monophosphate catabolic process 1/320 14/18722 0.214507087390391 0.356533903900682 UPP1 1 GO:0009159 deoxyribonucleoside monophosphate catabolic process 1/320 14/18722 0.214507087390391 0.356533903900682 UPP1 1 GO:0009173 pyrimidine ribonucleoside monophosphate metabolic process 1/320 14/18722 0.214507087390391 0.356533903900682 UPP1 1 GO:0009214 cyclic nucleotide catabolic process 1/320 14/18722 0.214507087390391 0.356533903900682 PDE4B 1 GO:0010457 centriole-centriole cohesion 1/320 14/18722 0.214507087390391 0.356533903900682 CTNNB1 1 GO:0018158 protein oxidation 1/320 14/18722 0.214507087390391 0.356533903900682 GPX1 1 GO:0022038 corpus callosum development 1/320 14/18722 0.214507087390391 0.356533903900682 C12orf57 1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway 1/320 14/18722 0.214507087390391 0.356533903900682 PDCD6 1 GO:0031115 negative regulation of microtubule polymerization 1/320 14/18722 0.214507087390391 0.356533903900682 STMN1 1 GO:0031650 regulation of heat generation 1/320 14/18722 0.214507087390391 0.356533903900682 ARRDC3 1 GO:0032688 negative regulation of interferon-beta production 1/320 14/18722 0.214507087390391 0.356533903900682 REL 1 GO:0034616 response to laminar fluid shear stress 1/320 14/18722 0.214507087390391 0.356533903900682 KLF2 1 GO:0035437 maintenance of protein localization in endoplasmic reticulum 1/320 14/18722 0.214507087390391 0.356533903900682 GJA1 1 GO:0035563 positive regulation of chromatin binding 1/320 14/18722 0.214507087390391 0.356533903900682 GMNN 1 GO:0035630 bone mineralization involved in bone maturation 1/320 14/18722 0.214507087390391 0.356533903900682 SNX10 1 GO:0035672 oligopeptide transmembrane transport 1/320 14/18722 0.214507087390391 0.356533903900682 GJA1 1 GO:0036151 phosphatidylcholine acyl-chain remodeling 1/320 14/18722 0.214507087390391 0.356533903900682 DBI 1 GO:0036295 cellular response to increased oxygen levels 1/320 14/18722 0.214507087390391 0.356533903900682 CAV1 1 GO:0038166 angiotensin-activated signaling pathway 1/320 14/18722 0.214507087390391 0.356533903900682 CAV1 1 GO:0043173 nucleotide salvage 1/320 14/18722 0.214507087390391 0.356533903900682 UPP1 1 GO:0043249 erythrocyte maturation 1/320 14/18722 0.214507087390391 0.356533903900682 KLF2 1 GO:0043455 regulation of secondary metabolic process 1/320 14/18722 0.214507087390391 0.356533903900682 ZEB2 1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 1/320 14/18722 0.214507087390391 0.356533903900682 PMAIP1 1 GO:0045006 DNA deamination 1/320 14/18722 0.214507087390391 0.356533903900682 APOBEC3A 1 GO:0045989 positive regulation of striated muscle contraction 1/320 14/18722 0.214507087390391 0.356533903900682 GSTO1 1 GO:0046049 UMP metabolic process 1/320 14/18722 0.214507087390391 0.356533903900682 UPP1 1 GO:0048021 regulation of melanin biosynthetic process 1/320 14/18722 0.214507087390391 0.356533903900682 ZEB2 1 GO:0048291 isotype switching to IgG isotypes 1/320 14/18722 0.214507087390391 0.356533903900682 PTPRC 1 GO:0050930 induction of positive chemotaxis 1/320 14/18722 0.214507087390391 0.356533903900682 PGF 1 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain 1/320 14/18722 0.214507087390391 0.356533903900682 CXCR4 1 GO:0051645 Golgi localization 1/320 14/18722 0.214507087390391 0.356533903900682 CDC42 1 GO:0060081 membrane hyperpolarization 1/320 14/18722 0.214507087390391 0.356533903900682 SOD2 1 GO:0060911 cardiac cell fate commitment 1/320 14/18722 0.214507087390391 0.356533903900682 ISL1 1 GO:0061043 regulation of vascular wound healing 1/320 14/18722 0.214507087390391 0.356533903900682 CXCR4 1 GO:0061709 reticulophagy 1/320 14/18722 0.214507087390391 0.356533903900682 UBA5 1 GO:0070278 extracellular matrix constituent secretion 1/320 14/18722 0.214507087390391 0.356533903900682 TNFRSF1B 1 GO:0070307 lens fiber cell development 1/320 14/18722 0.214507087390391 0.356533903900682 VIM 1 GO:0072350 tricarboxylic acid metabolic process 1/320 14/18722 0.214507087390391 0.356533903900682 IDH1 1 GO:0072498 embryonic skeletal joint development 1/320 14/18722 0.214507087390391 0.356533903900682 CTNNB1 1 GO:0097091 synaptic vesicle clustering 1/320 14/18722 0.214507087390391 0.356533903900682 CTNNB1 1 GO:0097531 mast cell migration 1/320 14/18722 0.214507087390391 0.356533903900682 PGF 1 GO:0098734 macromolecule depalmitoylation 1/320 14/18722 0.214507087390391 0.356533903900682 PPT1 1 GO:1900037 regulation of cellular response to hypoxia 1/320 14/18722 0.214507087390391 0.356533903900682 ENO1 1 GO:1900376 regulation of secondary metabolite biosynthetic process 1/320 14/18722 0.214507087390391 0.356533903900682 ZEB2 1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/320 14/18722 0.214507087390391 0.356533903900682 CD74 1 GO:1904152 regulation of retrograde protein transport, ER to cytosol 1/320 14/18722 0.214507087390391 0.356533903900682 UBE2J1 1 GO:1904294 positive regulation of ERAD pathway 1/320 14/18722 0.214507087390391 0.356533903900682 CAV1 1 GO:1904923 regulation of autophagy of mitochondrion in response to mitochondrial depolarization 1/320 14/18722 0.214507087390391 0.356533903900682 VPS13C 1 GO:1905065 positive regulation of vascular associated smooth muscle cell differentiation 1/320 14/18722 0.214507087390391 0.356533903900682 SOD2 1 GO:2001140 positive regulation of phospholipid transport 1/320 14/18722 0.214507087390391 0.356533903900682 DBI 1 GO:0045598 regulation of fat cell differentiation 4/320 139/18722 0.214608101758637 0.356558374132162 ADIRF/ZFP36/ZFP36L2/CEBPB 4 GO:0048285 organelle fission 11/320 488/18722 0.215399318234372 0.357729092823322 IGF2/FLNA/NEK6/CCSAP/CDC42/MKI67/HSPA1A/ACTR3/RHOA/TOP2A/CKS2 11 GO:0006120 mitochondrial electron transport, NADH to ubiquinone 2/320 51/18722 0.216692464742106 0.358650464356095 NDUFB1/NDUFB7 2 GO:0006636 unsaturated fatty acid biosynthetic process 2/320 51/18722 0.216692464742106 0.358650464356095 ANXA1/CD74 2 GO:0009948 anterior/posterior axis specification 2/320 51/18722 0.216692464742106 0.358650464356095 WLS/CTNNB1 2 GO:0010656 negative regulation of muscle cell apoptotic process 2/320 51/18722 0.216692464742106 0.358650464356095 HMOX1/PPP1R10 2 GO:0014009 glial cell proliferation 2/320 51/18722 0.216692464742106 0.358650464356095 TSPO/SOX4 2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 2/320 51/18722 0.216692464742106 0.358650464356095 STAT1/RHOA 2 GO:0050982 detection of mechanical stimulus 2/320 51/18722 0.216692464742106 0.358650464356095 CXCR4/CTNNB1 2 GO:0033044 regulation of chromosome organization 5/320 187/18722 0.216735287874436 0.358650464356095 NEK6/PARP1/PPP1R10/CTNNB1/TOP2A 5 GO:0061136 regulation of proteasomal protein catabolic process 5/320 187/18722 0.216735287874436 0.358650464356095 CAV1/GPX1/DDA1/HSPA1A/PBK 5 GO:1990830 cellular response to leukemia inhibitory factor 3/320 94/18722 0.217206344826531 0.359286075589762 NRP2/SNX10/TFRC 3 GO:0033673 negative regulation of kinase activity 6/320 237/18722 0.220578901813618 0.364718696396107 PTPRC/CAV1/MLLT1/PLEC/HSPB1/PDCD4 6 GO:0002532 production of molecular mediator involved in inflammatory response 3/320 95/18722 0.221682056425139 0.365345300317613 NCF1/EZH2/PDCD4 3 GO:0008585 female gonad development 3/320 95/18722 0.221682056425139 0.365345300317613 CYP19A1/IDH1/CEBPB 3 GO:0042773 ATP synthesis coupled electron transport 3/320 95/18722 0.221682056425139 0.365345300317613 NDUFB1/CDK1/NDUFB7 3 GO:0042775 mitochondrial ATP synthesis coupled electron transport 3/320 95/18722 0.221682056425139 0.365345300317613 NDUFB1/CDK1/NDUFB7 3 GO:0048709 oligodendrocyte differentiation 3/320 95/18722 0.221682056425139 0.365345300317613 TNFRSF1B/CXCR4/CTNNB1 3 GO:1990823 response to leukemia inhibitory factor 3/320 95/18722 0.221682056425139 0.365345300317613 NRP2/SNX10/TFRC 3 GO:0006119 oxidative phosphorylation 4/320 141/18722 0.221807806846722 0.365345300317613 NDUFB1/CDK1/NDUFB7/RHOA 4 GO:0016241 regulation of macroautophagy 4/320 141/18722 0.221807806846722 0.365345300317613 GAPDH/BNIP3L/HMOX1/VPS13C 4 GO:0048284 organelle fusion 4/320 141/18722 0.221807806846722 0.365345300317613 CORO1A/ANXA1/CDK1/TFRC 4 GO:0009060 aerobic respiration 5/320 189/18722 0.222902747627446 0.365345300317613 NDUFB1/CDK1/NDUFB7/RHOA/IDH1 5 GO:0046578 regulation of Ras protein signal transduction 5/320 189/18722 0.222902747627446 0.365345300317613 EPS8L1/ARHGDIB/TIMP2/ITGB1/STMN1 5 GO:0032206 positive regulation of telomere maintenance 2/320 52/18722 0.222991828230946 0.365345300317613 PPP1R10/CTNNB1 2 GO:0043090 amino acid import 2/320 52/18722 0.222991828230946 0.365345300317613 ITGB1/SLC43A2 2 GO:0060071 Wnt signaling pathway, planar cell polarity pathway 2/320 52/18722 0.222991828230946 0.365345300317613 CDC42/RHOA 2 GO:0072132 mesenchyme morphogenesis 2/320 52/18722 0.222991828230946 0.365345300317613 ISL1/TGFBR1 2 GO:0072523 purine-containing compound catabolic process 2/320 52/18722 0.222991828230946 0.365345300317613 SAMHD1/PDE4B 2 GO:2000378 negative regulation of reactive oxygen species metabolic process 2/320 52/18722 0.222991828230946 0.365345300317613 PAGE4/RHOA 2 GO:1901987 regulation of cell cycle phase transition 9/320 390/18722 0.225313629615324 0.365345300317613 AIF1/NEK6/ANXA1/ZFP36L2/PPP1R10/CDK1/EZH2/DBF4/SOX4 9 GO:2000045 regulation of G1/S transition of mitotic cell cycle 4/320 142/18722 0.225431517061893 0.365345300317613 AIF1/ANXA1/EZH2/SOX4 4 GO:0030510 regulation of BMP signaling pathway 3/320 96/18722 0.226176212809413 0.365345300317613 HTRA1/FBN1/LRP2 3 GO:0055017 cardiac muscle tissue growth 3/320 96/18722 0.226176212809413 0.365345300317613 TGFBR1/CDK1/GJA1 3 GO:1901655 cellular response to ketone 3/320 96/18722 0.226176212809413 0.365345300317613 MSN/KLF2/ATP2B1 3 GO:1904035 regulation of epithelial cell apoptotic process 3/320 96/18722 0.226176212809413 0.365345300317613 ZFP36/HMOX1/PDCD4 3 GO:0000478 endonucleolytic cleavage involved in rRNA processing 1/320 15/18722 0.227942929384996 0.365345300317613 RPS21 1 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/320 15/18722 0.227942929384996 0.365345300317613 RPS21 1 GO:0002679 respiratory burst involved in defense response 1/320 15/18722 0.227942929384996 0.365345300317613 NCF1 1 GO:0002730 regulation of dendritic cell cytokine production 1/320 15/18722 0.227942929384996 0.365345300317613 BST2 1 GO:0002836 positive regulation of response to tumor cell 1/320 15/18722 0.227942929384996 0.365345300317613 HLA-DRB1 1 GO:0002839 positive regulation of immune response to tumor cell 1/320 15/18722 0.227942929384996 0.365345300317613 HLA-DRB1 1 GO:0003356 regulation of cilium beat frequency 1/320 15/18722 0.227942929384996 0.365345300317613 CCSAP 1 GO:0006089 lactate metabolic process 1/320 15/18722 0.227942929384996 0.365345300317613 LDHA 1 GO:0006271 DNA strand elongation involved in DNA replication 1/320 15/18722 0.227942929384996 0.365345300317613 RFC3 1 GO:0006704 glucocorticoid biosynthetic process 1/320 15/18722 0.227942929384996 0.365345300317613 CYP11A1 1 GO:0010763 positive regulation of fibroblast migration 1/320 15/18722 0.227942929384996 0.365345300317613 ITGB1 1 GO:0010832 negative regulation of myotube differentiation 1/320 15/18722 0.227942929384996 0.365345300317613 BHLHE41 1 GO:0010889 regulation of sequestering of triglyceride 1/320 15/18722 0.227942929384996 0.365345300317613 PLIN2 1 GO:0010940 positive regulation of necrotic cell death 1/320 15/18722 0.227942929384996 0.365345300317613 TSPO 1 GO:0014744 positive regulation of muscle adaptation 1/320 15/18722 0.227942929384996 0.365345300317613 AIF1 1 GO:0016446 somatic hypermutation of immunoglobulin genes 1/320 15/18722 0.227942929384996 0.365345300317613 SAMHD1 1 GO:0019511 peptidyl-proline hydroxylation 1/320 15/18722 0.227942929384996 0.365345300317613 P4HA1 1 GO:0023035 CD40 signaling pathway 1/320 15/18722 0.227942929384996 0.365345300317613 ITGB1 1 GO:0030852 regulation of granulocyte differentiation 1/320 15/18722 0.227942929384996 0.365345300317613 EVI2B 1 GO:0031269 pseudopodium assembly 1/320 15/18722 0.227942929384996 0.365345300317613 CDC42 1 GO:0032486 Rap protein signal transduction 1/320 15/18722 0.227942929384996 0.365345300317613 TIMP2 1 GO:0032488 Cdc42 protein signal transduction 1/320 15/18722 0.227942929384996 0.365345300317613 CDC42 1 GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 1/320 15/18722 0.227942929384996 0.365345300317613 ISL1 1 GO:0032897 negative regulation of viral transcription 1/320 15/18722 0.227942929384996 0.365345300317613 ZFP36 1 GO:0033599 regulation of mammary gland epithelial cell proliferation 1/320 15/18722 0.227942929384996 0.365345300317613 GPX1 1 GO:0035627 ceramide transport 1/320 15/18722 0.227942929384996 0.365345300317613 PSAP 1 GO:0042159 lipoprotein catabolic process 1/320 15/18722 0.227942929384996 0.365345300317613 PPT1 1 GO:0043508 negative regulation of JUN kinase activity 1/320 15/18722 0.227942929384996 0.365345300317613 PDCD4 1 GO:0045064 T-helper 2 cell differentiation 1/320 15/18722 0.227942929384996 0.365345300317613 ANXA1 1 GO:0045176 apical protein localization 1/320 15/18722 0.227942929384996 0.365345300317613 ACTB 1 GO:0045725 positive regulation of glycogen biosynthetic process 1/320 15/18722 0.227942929384996 0.365345300317613 IGF2 1 GO:0046184 aldehyde biosynthetic process 1/320 15/18722 0.227942929384996 0.365345300317613 TPI1 1 GO:0048308 organelle inheritance 1/320 15/18722 0.227942929384996 0.365345300317613 CDK1 1 GO:0048313 Golgi inheritance 1/320 15/18722 0.227942929384996 0.365345300317613 CDK1 1 GO:0050746 regulation of lipoprotein metabolic process 1/320 15/18722 0.227942929384996 0.365345300317613 DBI 1 GO:0051775 response to redox state 1/320 15/18722 0.227942929384996 0.365345300317613 ARHGDIB 1 GO:0051791 medium-chain fatty acid metabolic process 1/320 15/18722 0.227942929384996 0.365345300317613 CROT 1 GO:0051938 L-glutamate import 1/320 15/18722 0.227942929384996 0.365345300317613 ITGB1 1 GO:0055012 ventricular cardiac muscle cell differentiation 1/320 15/18722 0.227942929384996 0.365345300317613 CDK1 1 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 1/320 15/18722 0.227942929384996 0.365345300317613 ZFP36 1 GO:0060253 negative regulation of glial cell proliferation 1/320 15/18722 0.227942929384996 0.365345300317613 TSPO 1 GO:0071871 response to epinephrine 1/320 15/18722 0.227942929384996 0.365345300317613 PDE4B 1 GO:0072075 metanephric mesenchyme development 1/320 15/18722 0.227942929384996 0.365345300317613 STAT1 1 GO:0080154 regulation of fertilization 1/320 15/18722 0.227942929384996 0.365345300317613 MYH9 1 GO:0086069 bundle of His cell to Purkinje myocyte communication 1/320 15/18722 0.227942929384996 0.365345300317613 DSP 1 GO:0090594 inflammatory response to wounding 1/320 15/18722 0.227942929384996 0.365345300317613 HMOX1 1 GO:0098712 L-glutamate import across plasma membrane 1/320 15/18722 0.227942929384996 0.365345300317613 ITGB1 1 GO:0110156 methylguanosine-cap decapping 1/320 15/18722 0.227942929384996 0.365345300317613 ZFP36 1 GO:0140374 antiviral innate immune response 1/320 15/18722 0.227942929384996 0.365345300317613 MX1 1 GO:1901660 calcium ion export 1/320 15/18722 0.227942929384996 0.365345300317613 ATP2B1 1 GO:1901741 positive regulation of myoblast fusion 1/320 15/18722 0.227942929384996 0.365345300317613 CD53 1 GO:1903729 regulation of plasma membrane organization 1/320 15/18722 0.227942929384996 0.365345300317613 MYH9 1 GO:1904424 regulation of GTP binding 1/320 15/18722 0.227942929384996 0.365345300317613 STMN1 1 GO:1905146 lysosomal protein catabolic process 1/320 15/18722 0.227942929384996 0.365345300317613 LRP2 1 GO:2000104 negative regulation of DNA-dependent DNA replication 1/320 15/18722 0.227942929384996 0.365345300317613 GMNN 1 GO:2001138 regulation of phospholipid transport 1/320 15/18722 0.227942929384996 0.365345300317613 DBI 1 GO:0006164 purine nucleotide biosynthetic process 5/320 191/18722 0.229122836342324 0.36695954307534 TMSB4X/ALDOA/ENO1/PARP1/PPT1 5 GO:0032784 regulation of DNA-templated transcription, elongation 2/320 53/18722 0.229305309830718 0.36695954307534 EZH2/CTNNB1 2 GO:0043113 receptor clustering 2/320 53/18722 0.229305309830718 0.36695954307534 ITGB2/FLNA 2 GO:1990090 cellular response to nerve growth factor stimulus 2/320 53/18722 0.229305309830718 0.36695954307534 CORO1A/ID1 2 GO:0016055 Wnt signaling pathway 10/320 444/18722 0.230413803166479 0.368590721906268 ZEB2/CAV1/WLS/ISL1/CDC42/PLPP3/RHOA/CTNNB1/SOX4/LGR5 10 GO:0035335 peptidyl-tyrosine dephosphorylation 3/320 97/18722 0.230687875120281 0.368886339008128 PTPRC/PTP4A2/PTPRA 3 GO:0010975 regulation of neuron projection development 10/320 445/18722 0.232432546644108 0.371532411115456 VIM/FLNA/FN1/RAB17/SEMA6D/B2M/S100A9/RHOA/ID1/EZH2 10 GO:0198738 cell-cell signaling by wnt 10/320 446/18722 0.234458014308115 0.374625102521706 ZEB2/CAV1/WLS/ISL1/CDC42/PLPP3/RHOA/CTNNB1/SOX4/LGR5 10 GO:0043473 pigmentation 3/320 98/18722 0.235216114084873 0.375545975038136 ZEB2/RAB17/CD63 3 GO:0043502 regulation of muscle adaptation 3/320 98/18722 0.235216114084873 0.375545975038136 TNFRSF1B/AIF1/PARP1 3 GO:0032330 regulation of chondrocyte differentiation 2/320 54/18722 0.235630595211649 0.376062425420831 TGFBR1/CTNNB1 2 GO:0061351 neural precursor cell proliferation 4/320 145/18722 0.236392180523772 0.37713223549198 FLNA/LRP2/RHOA/CTNNB1 4 GO:0010876 lipid localization 10/320 448/18722 0.238528827456498 0.377865144002523 CROT/TSPO/CAV1/PLIN2/ANXA1/CYP19A1/DBI/PSAP/SLC27A2/NPC2 10 GO:0003300 cardiac muscle hypertrophy 3/320 99/18722 0.239760010251014 0.377865144002523 TNFRSF1B/PARP1/EZH2 3 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 3/320 99/18722 0.239760010251014 0.377865144002523 TNFRSF1B/CD74/HMOX1 3 GO:0021510 spinal cord development 3/320 99/18722 0.239760010251014 0.377865144002523 LMO4/ISL1/SOX4 3 GO:0051153 regulation of striated muscle cell differentiation 3/320 99/18722 0.239760010251014 0.377865144002523 MORF4L2/BHLHE41/EZH2 3 GO:0001845 phagolysosome assembly 1/320 16/18722 0.241149657486605 0.377865144002523 CORO1A 1 GO:0002371 dendritic cell cytokine production 1/320 16/18722 0.241149657486605 0.377865144002523 BST2 1 GO:0002566 somatic diversification of immune receptors via somatic mutation 1/320 16/18722 0.241149657486605 0.377865144002523 SAMHD1 1 GO:0002693 positive regulation of cellular extravasation 1/320 16/18722 0.241149657486605 0.377865144002523 CD99 1 GO:0002830 positive regulation of type 2 immune response 1/320 16/18722 0.241149657486605 0.377865144002523 CD74 1 GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation 1/320 16/18722 0.241149657486605 0.377865144002523 TGFBR1 1 GO:0006349 regulation of gene expression by genetic imprinting 1/320 16/18722 0.241149657486605 0.377865144002523 IGF2 1 GO:0006857 oligopeptide transport 1/320 16/18722 0.241149657486605 0.377865144002523 GJA1 1 GO:0009299 mRNA transcription 1/320 16/18722 0.241149657486605 0.377865144002523 FLNA 1 GO:0009642 response to light intensity 1/320 16/18722 0.241149657486605 0.377865144002523 RDH13 1 GO:0010225 response to UV-C 1/320 16/18722 0.241149657486605 0.377865144002523 CARD16 1 GO:0010919 regulation of inositol phosphate biosynthetic process 1/320 16/18722 0.241149657486605 0.377865144002523 PLEK 1 GO:0019081 viral translation 1/320 16/18722 0.241149657486605 0.377865144002523 SSB 1 GO:0021783 preganglionic parasympathetic fiber development 1/320 16/18722 0.241149657486605 0.377865144002523 NRP2 1 GO:0030540 female genitalia development 1/320 16/18722 0.241149657486605 0.377865144002523 LRP2 1 GO:0031268 pseudopodium organization 1/320 16/18722 0.241149657486605 0.377865144002523 CDC42 1 GO:0032274 gonadotropin secretion 1/320 16/18722 0.241149657486605 0.377865144002523 GJA1 1 GO:0034138 toll-like receptor 3 signaling pathway 1/320 16/18722 0.241149657486605 0.377865144002523 CAV1 1 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter 1/320 16/18722 0.241149657486605 0.377865144002523 EZH2 1 GO:0035751 regulation of lysosomal lumen pH 1/320 16/18722 0.241149657486605 0.377865144002523 PPT1 1 GO:0042574 retinal metabolic process 1/320 16/18722 0.241149657486605 0.377865144002523 RDH13 1 GO:0042795 snRNA transcription by RNA polymerase II 1/320 16/18722 0.241149657486605 0.377865144002523 ICE1 1 GO:0043923 positive regulation by host of viral transcription 1/320 16/18722 0.241149657486605 0.377865144002523 JUN 1 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate 1/320 16/18722 0.241149657486605 0.377865144002523 APOBEC3A 1 GO:0050965 detection of temperature stimulus involved in sensory perception of pain 1/320 16/18722 0.241149657486605 0.377865144002523 CXCR4 1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis 1/320 16/18722 0.241149657486605 0.377865144002523 TNFRSF1B 1 GO:0060330 regulation of response to interferon-gamma 1/320 16/18722 0.241149657486605 0.377865144002523 PARP14 1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway 1/320 16/18722 0.241149657486605 0.377865144002523 PARP14 1 GO:0060572 morphogenesis of an epithelial bud 1/320 16/18722 0.241149657486605 0.377865144002523 CTNNB1 1 GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 1/320 16/18722 0.241149657486605 0.377865144002523 HSPA1A 1 GO:0071391 cellular response to estrogen stimulus 1/320 16/18722 0.241149657486605 0.377865144002523 SERPINB9 1 GO:0071639 positive regulation of monocyte chemotactic protein-1 production 1/320 16/18722 0.241149657486605 0.377865144002523 HMGB1 1 GO:0090520 sphingolipid mediated signaling pathway 1/320 16/18722 0.241149657486605 0.377865144002523 EZR 1 GO:0099116 tRNA 5'-end processing 1/320 16/18722 0.241149657486605 0.377865144002523 SSB 1 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration 1/320 16/18722 0.241149657486605 0.377865144002523 ATP2B1 1 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/320 16/18722 0.241149657486605 0.377865144002523 CD74 1 GO:1902931 negative regulation of alcohol biosynthetic process 1/320 16/18722 0.241149657486605 0.377865144002523 PLEK 1 GO:1904683 regulation of metalloendopeptidase activity 1/320 16/18722 0.241149657486605 0.377865144002523 TIMP3 1 GO:1904948 midbrain dopaminergic neuron differentiation 1/320 16/18722 0.241149657486605 0.377865144002523 CTNNB1 1 GO:2000001 regulation of DNA damage checkpoint 1/320 16/18722 0.241149657486605 0.377865144002523 PPP1R10 1 GO:2001224 positive regulation of neuron migration 1/320 16/18722 0.241149657486605 0.377865144002523 FLNA 1 GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 1/320 16/18722 0.241149657486605 0.377865144002523 PLAUR 1 GO:0030705 cytoskeleton-dependent intracellular transport 5/320 195/18722 0.241711239494625 0.378569184747834 ARMCX3/CDC42/DST/TUBB/HSPB1 5 GO:0006360 transcription by RNA polymerase I 2/320 55/18722 0.241965444559301 0.378569184747834 FLNA/POLR2L 2 GO:0031113 regulation of microtubule polymerization 2/320 55/18722 0.241965444559301 0.378569184747834 STMN1/HSPA1A 2 GO:0043331 response to dsRNA 2/320 55/18722 0.241965444559301 0.378569184747834 CAV1/PMAIP1 2 GO:1902652 secondary alcohol metabolic process 4/320 147/18722 0.243769010392452 0.381102365093307 CYP11A1/DHCR24/NPC2/IDH1 4 GO:1903531 negative regulation of secretion by cell 4/320 147/18722 0.243769010392452 0.381102365093307 TNFRSF1B/ANXA1/HMOX1/GJA1 4 GO:0048193 Golgi vesicle transport 7/320 296/18722 0.244185394115331 0.381608944207469 LAPTM5/VAMP5/KRT18/PLPP3/VPS13C/TMED4/PDCD6 7 GO:0046545 development of primary female sexual characteristics 3/320 100/18722 0.244318654206151 0.381672846570818 CYP19A1/IDH1/CEBPB 3 GO:0045664 regulation of neuron differentiation 5/320 196/18722 0.24488745557321 0.382416842943501 TIMP2/ISL1/NREP/B2M/RHOA 5 GO:0014074 response to purine-containing compound 4/320 148/18722 0.247476882704321 0.386168610020489 LDHA/EZR/JUN/STAT1 4 GO:0070507 regulation of microtubule cytoskeleton organization 4/320 148/18722 0.247476882704321 0.386168610020489 CCSAP/STMN1/HSPA1A/RHOA 4 GO:0042594 response to starvation 5/320 197/18722 0.248074712085846 0.386297958600411 UPP1/PAGE4/ZFP36/PMAIP1/JUN 5 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 2/320 56/18722 0.248307690717011 0.386297958600411 ZFP36/ZFP36L2 2 GO:0001658 branching involved in ureteric bud morphogenesis 2/320 56/18722 0.248307690717011 0.386297958600411 MAGED1/CTNNB1 2 GO:0015800 acidic amino acid transport 2/320 56/18722 0.248307690717011 0.386297958600411 ITGB1/GJA1 2 GO:0046456 icosanoid biosynthetic process 2/320 56/18722 0.248307690717011 0.386297958600411 ANXA1/CD74 2 GO:0090175 regulation of establishment of planar polarity 2/320 56/18722 0.248307690717011 0.386297958600411 CDC42/RHOA 2 GO:0098781 ncRNA transcription 2/320 56/18722 0.248307690717011 0.386297958600411 POLR2L/ICE1 2 GO:1990089 response to nerve growth factor 2/320 56/18722 0.248307690717011 0.386297958600411 CORO1A/ID1 2 GO:0006576 cellular biogenic amine metabolic process 3/320 101/18722 0.248891146781247 0.387059924162631 ITGB2/OAZ1/AZIN1 3 GO:0009411 response to UV 4/320 149/18722 0.251197082329001 0.388996466104169 GPX1/PARP1/PBK/CARD16 4 GO:0016525 negative regulation of angiogenesis 4/320 149/18722 0.251197082329001 0.388996466104169 KLF2/STAT1/PGK1/CTNNB1 4 GO:0032368 regulation of lipid transport 4/320 149/18722 0.251197082329001 0.388996466104169 TSPO/CAV1/CYP19A1/DBI 4 GO:0045834 positive regulation of lipid metabolic process 4/320 149/18722 0.251197082329001 0.388996466104169 ANXA1/CDC42/FLT1/CD74 4 GO:1901990 regulation of mitotic cell cycle phase transition 7/320 299/18722 0.251899314655366 0.388996466104169 AIF1/NEK6/ANXA1/ZFP36L2/CDK1/EZH2/SOX4 7 GO:0014897 striated muscle hypertrophy 3/320 102/18722 0.253476599240185 0.388996466104169 TNFRSF1B/PARP1/EZH2 3 GO:0006474 N-terminal protein amino acid acetylation 1/320 17/18722 0.254131166606903 0.388996466104169 SOX4 1 GO:0006577 amino-acid betaine metabolic process 1/320 17/18722 0.254131166606903 0.388996466104169 CROT 1 GO:0006895 Golgi to endosome transport 1/320 17/18722 0.254131166606903 0.388996466104169 VPS13C 1 GO:0006901 vesicle coating 1/320 17/18722 0.254131166606903 0.388996466104169 PDCD6 1 GO:0007625 grooming behavior 1/320 17/18722 0.254131166606903 0.388996466104169 PPT1 1 GO:0008334 histone mRNA metabolic process 1/320 17/18722 0.254131166606903 0.388996466104169 SSB 1 GO:0009151 purine deoxyribonucleotide metabolic process 1/320 17/18722 0.254131166606903 0.388996466104169 SAMHD1 1 GO:0009200 deoxyribonucleoside triphosphate metabolic process 1/320 17/18722 0.254131166606903 0.388996466104169 SAMHD1 1 GO:0015867 ATP transport 1/320 17/18722 0.254131166606903 0.388996466104169 GJA1 1 GO:0032604 granulocyte macrophage colony-stimulating factor production 1/320 17/18722 0.254131166606903 0.388996466104169 ISL1 1 GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 1/320 17/18722 0.254131166606903 0.388996466104169 ISL1 1 GO:0033151 V(D)J recombination 1/320 17/18722 0.254131166606903 0.388996466104169 HMGB1 1 GO:0033623 regulation of integrin activation 1/320 17/18722 0.254131166606903 0.388996466104169 PLEK 1 GO:0036166 phenotypic switching 1/320 17/18722 0.254131166606903 0.388996466104169 SOD2 1 GO:0042053 regulation of dopamine metabolic process 1/320 17/18722 0.254131166606903 0.388996466104169 ITGB2 1 GO:0042069 regulation of catecholamine metabolic process 1/320 17/18722 0.254131166606903 0.388996466104169 ITGB2 1 GO:0043968 histone H2A acetylation 1/320 17/18722 0.254131166606903 0.388996466104169 MORF4L2 1 GO:0044539 long-chain fatty acid import into cell 1/320 17/18722 0.254131166606903 0.388996466104169 SLC27A2 1 GO:0045815 positive regulation of gene expression, epigenetic 1/320 17/18722 0.254131166606903 0.388996466104169 CDCA4 1 GO:0048521 negative regulation of behavior 1/320 17/18722 0.254131166606903 0.388996466104169 ARRDC3 1 GO:0048532 anatomical structure arrangement 1/320 17/18722 0.254131166606903 0.388996466104169 NRP2 1 GO:0051580 regulation of neurotransmitter uptake 1/320 17/18722 0.254131166606903 0.388996466104169 ITGB1 1 GO:0055119 relaxation of cardiac muscle 1/320 17/18722 0.254131166606903 0.388996466104169 PDE4B 1 GO:0060033 anatomical structure regression 1/320 17/18722 0.254131166606903 0.388996466104169 FLT1 1 GO:0060263 regulation of respiratory burst 1/320 17/18722 0.254131166606903 0.388996466104169 NCF1 1 GO:0061298 retina vasculature development in camera-type eye 1/320 17/18722 0.254131166606903 0.388996466104169 CLIC4 1 GO:0070206 protein trimerization 1/320 17/18722 0.254131166606903 0.388996466104169 CD74 1 GO:0070593 dendrite self-avoidance 1/320 17/18722 0.254131166606903 0.388996466104169 EMB 1 GO:0090036 regulation of protein kinase C signaling 1/320 17/18722 0.254131166606903 0.388996466104169 MYADM 1 GO:0090083 regulation of inclusion body assembly 1/320 17/18722 0.254131166606903 0.388996466104169 HSPA1A 1 GO:0090136 epithelial cell-cell adhesion 1/320 17/18722 0.254131166606903 0.388996466104169 DSP 1 GO:0140354 lipid import into cell 1/320 17/18722 0.254131166606903 0.388996466104169 SLC27A2 1 GO:1903830 magnesium ion transmembrane transport 1/320 17/18722 0.254131166606903 0.388996466104169 TUSC3 1 GO:0016050 vesicle organization 7/320 300/18722 0.254487027744392 0.388996466104169 ZEB2/SRGN/CORO1A/CAV1/ANXA1/SNX10/PDCD6 7 GO:0002011 morphogenesis of an epithelial sheet 2/320 57/18722 0.254655237369743 0.388996466104169 FLNA/RHOA 2 GO:0010257 NADH dehydrogenase complex assembly 2/320 57/18722 0.254655237369743 0.388996466104169 NDUFB1/NDUFB7 2 GO:0016447 somatic recombination of immunoglobulin gene segments 2/320 57/18722 0.254655237369743 0.388996466104169 PTPRC/TFRC 2 GO:0032981 mitochondrial respiratory chain complex I assembly 2/320 57/18722 0.254655237369743 0.388996466104169 NDUFB1/NDUFB7 2 GO:0050879 multicellular organismal movement 2/320 57/18722 0.254655237369743 0.388996466104169 C12orf57/GSTO1 2 GO:0050881 musculoskeletal movement 2/320 57/18722 0.254655237369743 0.388996466104169 C12orf57/GSTO1 2 GO:0050891 multicellular organismal water homeostasis 2/320 57/18722 0.254655237369743 0.388996466104169 STMN1/PLEC 2 GO:0061005 cell differentiation involved in kidney development 2/320 57/18722 0.254655237369743 0.388996466104169 STAT1/CTNNB1 2 GO:0006887 exocytosis 8/320 352/18722 0.255780568714166 0.390571067970043 PLEK/ITGB2/CORO1A/CCL3/ANXA1/MYH9/HMOX1/STXBP2 8 GO:0006913 nucleocytoplasmic transport 7/320 301/18722 0.257082687344447 0.392269447602383 TXNIP/FLNA/RPL23/PTTG1IP/SSB/PPP1R10/CDK1 7 GO:0051169 nuclear transport 7/320 301/18722 0.257082687344447 0.392269447602383 TXNIP/FLNA/RPL23/PTTG1IP/SSB/PPP1R10/CDK1 7 GO:0072522 purine-containing compound biosynthetic process 5/320 200/18722 0.257699696967286 0.3930657614872 TMSB4X/ALDOA/ENO1/PARP1/PPT1 5 GO:0046425 regulation of receptor signaling pathway via JAK-STAT 3/320 103/18722 0.258074133455172 0.393491630788476 PTPRC/CAV1/PARP14 3 GO:0006261 DNA-dependent DNA replication 4/320 151/18722 0.258672542812654 0.393967912606667 SAMHD1/RFC3/GMNN/DBF4 4 GO:0048592 eye morphogenesis 4/320 151/18722 0.258672542812654 0.393967912606667 RDH13/FBN1/C12orf57/CTNNB1 4 GO:2000181 negative regulation of blood vessel morphogenesis 4/320 151/18722 0.258672542812654 0.393967912606667 KLF2/STAT1/PGK1/CTNNB1 4 GO:0009952 anterior/posterior pattern specification 5/320 201/18722 0.26092808900191 0.396644732855214 BHLHE40/WLS/TGFBR1/BHLHE41/CTNNB1 5 GO:0002931 response to ischemia 2/320 58/18722 0.261006057268472 0.396644732855214 CAV1/GJA1 2 GO:0043666 regulation of phosphoprotein phosphatase activity 2/320 58/18722 0.261006057268472 0.396644732855214 PTPRC/SLC39A10 2 GO:0045604 regulation of epidermal cell differentiation 2/320 58/18722 0.261006057268472 0.396644732855214 ZFP36/EZH2 2 GO:2000649 regulation of sodium ion transmembrane transporter activity 2/320 58/18722 0.261006057268472 0.396644732855214 FXYD5/FXYD3 2 GO:2000736 regulation of stem cell differentiation 2/320 58/18722 0.261006057268472 0.396644732855214 LBH/ZFP36L2 2 GO:0016125 sterol metabolic process 4/320 152/18722 0.262426848831009 0.39836434216375 CYP11A1/CYP19A1/DHCR24/NPC2 4 GO:0030509 BMP signaling pathway 4/320 152/18722 0.262426848831009 0.39836434216375 HTRA1/FBN1/LRP2/PDCD4 4 GO:1901343 negative regulation of vasculature development 4/320 152/18722 0.262426848831009 0.39836434216375 KLF2/STAT1/PGK1/CTNNB1 4 GO:0060419 heart growth 3/320 104/18722 0.262682882068654 0.398606562140169 TGFBR1/CDK1/GJA1 3 GO:0060828 regulation of canonical Wnt signaling pathway 6/320 253/18722 0.265611207914936 0.399683083618788 ZEB2/CAV1/WLS/ISL1/SOX4/LGR5 6 GO:0000712 resolution of meiotic recombination intermediates 1/320 18/18722 0.26689128564918 0.399683083618788 TOP2A 1 GO:0002223 stimulatory C-type lectin receptor signaling pathway 1/320 18/18722 0.26689128564918 0.399683083618788 TYROBP 1 GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 1/320 18/18722 0.26689128564918 0.399683083618788 PTPRC 1 GO:0003417 growth plate cartilage development 1/320 18/18722 0.26689128564918 0.399683083618788 ANXA6 1 GO:0006103 2-oxoglutarate metabolic process 1/320 18/18722 0.26689128564918 0.399683083618788 IDH1 1 GO:0009125 nucleoside monophosphate catabolic process 1/320 18/18722 0.26689128564918 0.399683083618788 UPP1 1 GO:0015693 magnesium ion transport 1/320 18/18722 0.26689128564918 0.399683083618788 TUSC3 1 GO:0015936 coenzyme A metabolic process 1/320 18/18722 0.26689128564918 0.399683083618788 CROT 1 GO:0019896 axonal transport of mitochondrion 1/320 18/18722 0.26689128564918 0.399683083618788 ARMCX3 1 GO:0030730 sequestering of triglyceride 1/320 18/18722 0.26689128564918 0.399683083618788 PLIN2 1 GO:0031643 positive regulation of myelination 1/320 18/18722 0.26689128564918 0.399683083618788 TNFRSF1B 1 GO:0031649 heat generation 1/320 18/18722 0.26689128564918 0.399683083618788 ARRDC3 1 GO:0032769 negative regulation of monooxygenase activity 1/320 18/18722 0.26689128564918 0.399683083618788 CAV1 1 GO:0032785 negative regulation of DNA-templated transcription, elongation 1/320 18/18722 0.26689128564918 0.399683083618788 EZH2 1 GO:0034162 toll-like receptor 9 signaling pathway 1/320 18/18722 0.26689128564918 0.399683083618788 HMGB1 1 GO:0045623 negative regulation of T-helper cell differentiation 1/320 18/18722 0.26689128564918 0.399683083618788 ANXA1 1 GO:0048486 parasympathetic nervous system development 1/320 18/18722 0.26689128564918 0.399683083618788 NRP2 1 GO:0051782 negative regulation of cell division 1/320 18/18722 0.26689128564918 0.399683083618788 TXNIP 1 GO:0060008 Sertoli cell differentiation 1/320 18/18722 0.26689128564918 0.399683083618788 FLNA 1 GO:0060192 negative regulation of lipase activity 1/320 18/18722 0.26689128564918 0.399683083618788 ANXA1 1 GO:0060438 trachea development 1/320 18/18722 0.26689128564918 0.399683083618788 CTNNB1 1 GO:0061484 hematopoietic stem cell homeostasis 1/320 18/18722 0.26689128564918 0.399683083618788 SOX4 1 GO:0071071 regulation of phospholipid biosynthetic process 1/320 18/18722 0.26689128564918 0.399683083618788 IDH1 1 GO:0071360 cellular response to exogenous dsRNA 1/320 18/18722 0.26689128564918 0.399683083618788 CAV1 1 GO:0072079 nephron tubule formation 1/320 18/18722 0.26689128564918 0.399683083618788 CTNNB1 1 GO:0072234 metanephric nephron tubule development 1/320 18/18722 0.26689128564918 0.399683083618788 STAT1 1 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis 1/320 18/18722 0.26689128564918 0.399683083618788 MAGED1 1 GO:0090493 catecholamine uptake 1/320 18/18722 0.26689128564918 0.399683083618788 ACTB 1 GO:0110154 RNA decapping 1/320 18/18722 0.26689128564918 0.399683083618788 ZFP36 1 GO:0150078 positive regulation of neuroinflammatory response 1/320 18/18722 0.26689128564918 0.399683083618788 CCL3 1 GO:1900006 positive regulation of dendrite development 1/320 18/18722 0.26689128564918 0.399683083618788 EZH2 1 GO:1900424 regulation of defense response to bacterium 1/320 18/18722 0.26689128564918 0.399683083618788 CYBA 1 GO:1902683 regulation of receptor localization to synapse 1/320 18/18722 0.26689128564918 0.399683083618788 TYROBP 1 GO:1990840 response to lectin 1/320 18/18722 0.26689128564918 0.399683083618788 TYROBP 1 GO:1990858 cellular response to lectin 1/320 18/18722 0.26689128564918 0.399683083618788 TYROBP 1 GO:0006325 chromatin organization 9/320 409/18722 0.267058794107312 0.399683083618788 MBD3/HMGN2/HMGB1/HMGN3/DEK/MKI67/GPX4/EZH2/ACTB 9 GO:0006767 water-soluble vitamin metabolic process 2/320 59/18722 0.267358190494271 0.399683083618788 SLC2A3/GSTO1 2 GO:0043407 negative regulation of MAP kinase activity 2/320 59/18722 0.267358190494271 0.399683083618788 CAV1/PDCD4 2 GO:0043551 regulation of phosphatidylinositol 3-kinase activity 2/320 59/18722 0.267358190494271 0.399683083618788 CDC42/FLT1 2 GO:0048278 vesicle docking 2/320 59/18722 0.267358190494271 0.399683083618788 PLEK/STXBP2 2 GO:0002062 chondrocyte differentiation 3/320 106/18722 0.27193060779295 0.406224610050785 TGFBR1/ANXA6/CTNNB1 3 GO:2000278 regulation of DNA biosynthetic process 3/320 106/18722 0.27193060779295 0.406224610050785 RFC3/CTNNB1/GJA1 3 GO:0006893 Golgi to plasma membrane transport 2/320 60/18722 0.273709742761259 0.407910788884769 VAMP5/KRT18 2 GO:0019731 antibacterial humoral response 2/320 60/18722 0.273709742761259 0.407910788884769 HLA-A/HLA-E 2 GO:0042306 regulation of protein import into nucleus 2/320 60/18722 0.273709742761259 0.407910788884769 FLNA/CDK1 2 GO:0051851 modulation by host of symbiont process 2/320 60/18722 0.273709742761259 0.407910788884769 CCL3/JUN 2 GO:0061951 establishment of protein localization to plasma membrane 2/320 60/18722 0.273709742761259 0.407910788884769 VAMP5/KRT18 2 GO:0010970 transport along microtubule 4/320 155/18722 0.273750391475669 0.407910788884769 ARMCX3/CDC42/DST/HSPB1 4 GO:0046434 organophosphate catabolic process 4/320 155/18722 0.273750391475669 0.407910788884769 UPP1/SAMHD1/PDE4B/IDH1 4 GO:0071868 cellular response to monoamine stimulus 3/320 107/18722 0.276567905317701 0.409585091618457 FLNA/PDE4B/ID1 3 GO:0071870 cellular response to catecholamine stimulus 3/320 107/18722 0.276567905317701 0.409585091618457 FLNA/PDE4B/ID1 3 GO:0001764 neuron migration 4/320 156/18722 0.277543551675852 0.409585091618457 FLNA/CXCR4/NRP2/CTNNB1 4 GO:0001696 gastric acid secretion 1/320 19/18722 0.279433778623531 0.409585091618457 SNX10 1 GO:0002523 leukocyte migration involved in inflammatory response 1/320 19/18722 0.279433778623531 0.409585091618457 S100A9 1 GO:0003085 negative regulation of systemic arterial blood pressure 1/320 19/18722 0.279433778623531 0.409585091618457 SOD2 1 GO:0006007 glucose catabolic process 1/320 19/18722 0.279433778623531 0.409585091618457 ENO1 1 GO:0006071 glycerol metabolic process 1/320 19/18722 0.279433778623531 0.409585091618457 TPI1 1 GO:0006670 sphingosine metabolic process 1/320 19/18722 0.279433778623531 0.409585091618457 PLPP3 1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 1/320 19/18722 0.279433778623531 0.409585091618457 SOX4 1 GO:0007039 protein catabolic process in the vacuole 1/320 19/18722 0.279433778623531 0.409585091618457 LRP2 1 GO:0008356 asymmetric cell division 1/320 19/18722 0.279433778623531 0.409585091618457 ACTR3 1 GO:0009223 pyrimidine deoxyribonucleotide catabolic process 1/320 19/18722 0.279433778623531 0.409585091618457 UPP1 1 GO:0009301 snRNA transcription 1/320 19/18722 0.279433778623531 0.409585091618457 ICE1 1 GO:0010002 cardioblast differentiation 1/320 19/18722 0.279433778623531 0.409585091618457 ISL1 1 GO:0019373 epoxygenase P450 pathway 1/320 19/18722 0.279433778623531 0.409585091618457 CYP2J2 1 GO:0030011 maintenance of cell polarity 1/320 19/18722 0.279433778623531 0.409585091618457 DST 1 GO:0030220 platelet formation 1/320 19/18722 0.279433778623531 0.409585091618457 MYH9 1 GO:0031290 retinal ganglion cell axon guidance 1/320 19/18722 0.279433778623531 0.409585091618457 ISL1 1 GO:0032616 interleukin-13 production 1/320 19/18722 0.279433778623531 0.409585091618457 HLA-E 1 GO:0032656 regulation of interleukin-13 production 1/320 19/18722 0.279433778623531 0.409585091618457 HLA-E 1 GO:0034501 protein localization to kinetochore 1/320 19/18722 0.279433778623531 0.409585091618457 CDK1 1 GO:0035461 vitamin transmembrane transport 1/320 19/18722 0.279433778623531 0.409585091618457 LRP2 1 GO:0036344 platelet morphogenesis 1/320 19/18722 0.279433778623531 0.409585091618457 MYH9 1 GO:0043031 negative regulation of macrophage activation 1/320 19/18722 0.279433778623531 0.409585091618457 PTPRC 1 GO:0044003 modulation by symbiont of host process 1/320 19/18722 0.279433778623531 0.409585091618457 SERPINB9 1 GO:0045603 positive regulation of endothelial cell differentiation 1/320 19/18722 0.279433778623531 0.409585091618457 CTNNB1 1 GO:0045780 positive regulation of bone resorption 1/320 19/18722 0.279433778623531 0.409585091618457 TFRC 1 GO:0046716 muscle cell cellular homeostasis 1/320 19/18722 0.279433778623531 0.409585091618457 ALDOA 1 GO:0046782 regulation of viral transcription 1/320 19/18722 0.279433778623531 0.409585091618457 ZFP36 1 GO:0048245 eosinophil chemotaxis 1/320 19/18722 0.279433778623531 0.409585091618457 CCL3 1 GO:0050961 detection of temperature stimulus involved in sensory perception 1/320 19/18722 0.279433778623531 0.409585091618457 CXCR4 1 GO:0051571 positive regulation of histone H3-K4 methylation 1/320 19/18722 0.279433778623531 0.409585091618457 CTNNB1 1 GO:0051957 positive regulation of amino acid transport 1/320 19/18722 0.279433778623531 0.409585091618457 ITGB1 1 GO:0060216 definitive hemopoiesis 1/320 19/18722 0.279433778623531 0.409585091618457 ZFP36L2 1 GO:0070233 negative regulation of T cell apoptotic process 1/320 19/18722 0.279433778623531 0.409585091618457 TSC22D3 1 GO:0070734 histone H3-K27 methylation 1/320 19/18722 0.279433778623531 0.409585091618457 EZH2 1 GO:0072074 kidney mesenchyme development 1/320 19/18722 0.279433778623531 0.409585091618457 STAT1 1 GO:0098780 response to mitochondrial depolarisation 1/320 19/18722 0.279433778623531 0.409585091618457 VPS13C 1 GO:0140131 positive regulation of lymphocyte chemotaxis 1/320 19/18722 0.279433778623531 0.409585091618457 CCL3 1 GO:1901739 regulation of myoblast fusion 1/320 19/18722 0.279433778623531 0.409585091618457 CD53 1 GO:1901881 positive regulation of protein depolymerization 1/320 19/18722 0.279433778623531 0.409585091618457 PLEK 1 GO:1903083 protein localization to condensed chromosome 1/320 19/18722 0.279433778623531 0.409585091618457 CDK1 1 GO:1903204 negative regulation of oxidative stress-induced neuron death 1/320 19/18722 0.279433778623531 0.409585091618457 CTNNB1 1 GO:1903975 regulation of glial cell migration 1/320 19/18722 0.279433778623531 0.409585091618457 CCL3 1 GO:2000251 positive regulation of actin cytoskeleton reorganization 1/320 19/18722 0.279433778623531 0.409585091618457 CDC42 1 GO:0042255 ribosome assembly 2/320 61/18722 0.28005888375759 0.410210318215655 RPS27/RPS28 2 GO:1904356 regulation of telomere maintenance via telomere lengthening 2/320 61/18722 0.28005888375759 0.410210318215655 PARP1/CTNNB1 2 GO:0007030 Golgi organization 4/320 157/18722 0.281345260713851 0.41180255659569 SYNE1/CDC42/CDK1/TMED4 4 GO:0007034 vacuolar transport 4/320 157/18722 0.281345260713851 0.41180255659569 LAPTM5/PSAP/HSPA1A/VPS13C 4 GO:0072009 nephron epithelium development 3/320 109/18722 0.285865255240025 0.417727034840773 STAT1/MAGED1/CTNNB1 3 GO:0009116 nucleoside metabolic process 2/320 62/18722 0.286403845523695 0.417727034840773 UPP1/APOBEC3A 2 GO:0045576 mast cell activation 2/320 62/18722 0.286403845523695 0.417727034840773 HMOX1/STXBP2 2 GO:0046148 pigment biosynthetic process 2/320 62/18722 0.286403845523695 0.417727034840773 ZEB2/TSPO 2 GO:0046173 polyol biosynthetic process 2/320 62/18722 0.286403845523695 0.417727034840773 PLEK/ISYNA1 2 GO:0046824 positive regulation of nucleocytoplasmic transport 2/320 62/18722 0.286403845523695 0.417727034840773 FLNA/CDK1 2 GO:0048488 synaptic vesicle endocytosis 2/320 62/18722 0.286403845523695 0.417727034840773 ACTG1/ACTB 2 GO:0060675 ureteric bud morphogenesis 2/320 62/18722 0.286403845523695 0.417727034840773 MAGED1/CTNNB1 2 GO:0140238 presynaptic endocytosis 2/320 62/18722 0.286403845523695 0.417727034840773 ACTG1/ACTB 2 GO:1903078 positive regulation of protein localization to plasma membrane 2/320 62/18722 0.286403845523695 0.417727034840773 EZR/ITGB1 2 GO:0003014 renal system process 3/320 110/18722 0.290523696088074 0.421525179234682 CYBA/RHOA/GJA1 3 GO:0006939 smooth muscle contraction 3/320 110/18722 0.290523696088074 0.421525179234682 CAV1/ATP2B1/RHOA 3 GO:0007088 regulation of mitotic nuclear division 3/320 110/18722 0.290523696088074 0.421525179234682 IGF2/CDC42/MKI67 3 GO:0009408 response to heat 3/320 110/18722 0.290523696088074 0.421525179234682 HMOX1/HSPA1A/PDCD6 3 GO:0018958 phenol-containing compound metabolic process 3/320 110/18722 0.290523696088074 0.421525179234682 ZEB2/ITGB2/CTSB 3 GO:0048259 regulation of receptor-mediated endocytosis 3/320 110/18722 0.290523696088074 0.421525179234682 CD63/B2M/PPT1 3 GO:0006605 protein targeting 7/320 314/18722 0.291478676528481 0.421525179234682 ITGB2/NCF1/TSPO/LAPTM5/BNIP3L/TCAF1/VPS13C 7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle 1/320 20/18722 0.29176234574327 0.421525179234682 BACH1 1 GO:0006346 DNA methylation-dependent heterochromatin assembly 1/320 20/18722 0.29176234574327 0.421525179234682 MBD3 1 GO:0006590 thyroid hormone generation 1/320 20/18722 0.29176234574327 0.421525179234682 CTSB 1 GO:0006896 Golgi to vacuole transport 1/320 20/18722 0.29176234574327 0.421525179234682 LAPTM5 1 GO:0007097 nuclear migration 1/320 20/18722 0.29176234574327 0.421525179234682 CDC42 1 GO:0009129 pyrimidine nucleoside monophosphate metabolic process 1/320 20/18722 0.29176234574327 0.421525179234682 UPP1 1 GO:0014047 glutamate secretion 1/320 20/18722 0.29176234574327 0.421525179234682 GJA1 1 GO:0016553 base conversion or substitution editing 1/320 20/18722 0.29176234574327 0.421525179234682 APOBEC3A 1 GO:0021516 dorsal spinal cord development 1/320 20/18722 0.29176234574327 0.421525179234682 LMO4 1 GO:0032495 response to muramyl dipeptide 1/320 20/18722 0.29176234574327 0.421525179234682 VIM 1 GO:0032986 protein-DNA complex disassembly 1/320 20/18722 0.29176234574327 0.421525179234682 RPL23 1 GO:0043586 tongue development 1/320 20/18722 0.29176234574327 0.421525179234682 CTNNB1 1 GO:0043651 linoleic acid metabolic process 1/320 20/18722 0.29176234574327 0.421525179234682 CYP2J2 1 GO:0060044 negative regulation of cardiac muscle cell proliferation 1/320 20/18722 0.29176234574327 0.421525179234682 GJA1 1 GO:0060252 positive regulation of glial cell proliferation 1/320 20/18722 0.29176234574327 0.421525179234682 TSPO 1 GO:0090201 negative regulation of release of cytochrome c from mitochondria 1/320 20/18722 0.29176234574327 0.421525179234682 GPX1 1 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/320 20/18722 0.29176234574327 0.421525179234682 HSPA1A 1 GO:1903817 negative regulation of voltage-gated potassium channel activity 1/320 20/18722 0.29176234574327 0.421525179234682 CAV1 1 GO:1904292 regulation of ERAD pathway 1/320 20/18722 0.29176234574327 0.421525179234682 CAV1 1 GO:2000010 positive regulation of protein localization to cell surface 1/320 20/18722 0.29176234574327 0.421525179234682 TYROBP 1 GO:0016239 positive regulation of macroautophagy 2/320 63/18722 0.292742920866992 0.422203751840284 BNIP3L/HMOX1 2 GO:0022617 extracellular matrix disassembly 2/320 63/18722 0.292742920866992 0.422203751840284 CTSS/LCP1 2 GO:0072171 mesonephric tubule morphogenesis 2/320 63/18722 0.292742920866992 0.422203751840284 MAGED1/CTNNB1 2 GO:1904589 regulation of protein import 2/320 63/18722 0.292742920866992 0.422203751840284 FLNA/CDK1 2 GO:2000756 regulation of peptidyl-lysine acetylation 2/320 63/18722 0.292742920866992 0.422203751840284 ISL1/SOX4 2 GO:0042180 cellular ketone metabolic process 5/320 211/18722 0.293686573955226 0.423416930768665 CAV1/TPI1/CYP11A1/ANXA1/CD74 5 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 3/320 111/18722 0.295187592381912 0.425135981778341 NCF1/FN1/FLT1 3 GO:0071867 response to monoamine 3/320 111/18722 0.295187592381912 0.425135981778341 FLNA/PDE4B/ID1 3 GO:0071869 response to catecholamine 3/320 111/18722 0.295187592381912 0.425135981778341 FLNA/PDE4B/ID1 3 GO:0030104 water homeostasis 2/320 64/18722 0.299074461812294 0.430284009821866 STMN1/PLEC 2 GO:1900076 regulation of cellular response to insulin stimulus 2/320 64/18722 0.299074461812294 0.430284009821866 IGF2/ATP2B1 2 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process 2/320 64/18722 0.299074461812294 0.430284009821866 RPL23/PBK 2 GO:0000956 nuclear-transcribed mRNA catabolic process 3/320 112/18722 0.299856167288407 0.430808652029102 ZFP36/ZFP36L2/SSB 3 GO:0035601 protein deacylation 3/320 112/18722 0.299856167288407 0.430808652029102 FLNA/MORF4L2/PPT1 3 GO:0043406 positive regulation of MAP kinase activity 3/320 112/18722 0.299856167288407 0.430808652029102 FLT1/MAGED1/EZH2 3 GO:0048640 negative regulation of developmental growth 3/320 112/18722 0.299856167288407 0.430808652029102 PLAC8/SEMA6D/GJA1 3 GO:0000002 mitochondrial genome maintenance 1/320 21/18722 0.303880624502876 0.432381108968968 PARP1 1 GO:0003177 pulmonary valve development 1/320 21/18722 0.303880624502876 0.432381108968968 TNFRSF1B 1 GO:0006244 pyrimidine nucleotide catabolic process 1/320 21/18722 0.303880624502876 0.432381108968968 UPP1 1 GO:0007063 regulation of sister chromatid cohesion 1/320 21/18722 0.303880624502876 0.432381108968968 CTNNB1 1 GO:0007350 blastoderm segmentation 1/320 21/18722 0.303880624502876 0.432381108968968 NRP2 1 GO:0008090 retrograde axonal transport 1/320 21/18722 0.303880624502876 0.432381108968968 DST 1 GO:0023019 signal transduction involved in regulation of gene expression 1/320 21/18722 0.303880624502876 0.432381108968968 PARP1 1 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation 1/320 21/18722 0.303880624502876 0.432381108968968 GMFG 1 GO:0034471 ncRNA 5'-end processing 1/320 21/18722 0.303880624502876 0.432381108968968 SSB 1 GO:0038083 peptidyl-tyrosine autophosphorylation 1/320 21/18722 0.303880624502876 0.432381108968968 CAV1 1 GO:0043373 CD4-positive, alpha-beta T cell lineage commitment 1/320 21/18722 0.303880624502876 0.432381108968968 CTSL 1 GO:0044342 type B pancreatic cell proliferation 1/320 21/18722 0.303880624502876 0.432381108968968 SERPINB1 1 GO:0046519 sphingoid metabolic process 1/320 21/18722 0.303880624502876 0.432381108968968 PLPP3 1 GO:0046885 regulation of hormone biosynthetic process 1/320 21/18722 0.303880624502876 0.432381108968968 STC2 1 GO:0048199 vesicle targeting, to, from or within Golgi 1/320 21/18722 0.303880624502876 0.432381108968968 PDCD6 1 GO:0050849 negative regulation of calcium-mediated signaling 1/320 21/18722 0.303880624502876 0.432381108968968 PLEK 1 GO:0051152 positive regulation of smooth muscle cell differentiation 1/320 21/18722 0.303880624502876 0.432381108968968 SOD2 1 GO:0070584 mitochondrion morphogenesis 1/320 21/18722 0.303880624502876 0.432381108968968 PLEC 1 GO:0071605 monocyte chemotactic protein-1 production 1/320 21/18722 0.303880624502876 0.432381108968968 HMGB1 1 GO:0071637 regulation of monocyte chemotactic protein-1 production 1/320 21/18722 0.303880624502876 0.432381108968968 HMGB1 1 GO:0072111 cell proliferation involved in kidney development 1/320 21/18722 0.303880624502876 0.432381108968968 STAT1 1 GO:0072170 metanephric tubule development 1/320 21/18722 0.303880624502876 0.432381108968968 STAT1 1 GO:0072243 metanephric nephron epithelium development 1/320 21/18722 0.303880624502876 0.432381108968968 STAT1 1 GO:0090189 regulation of branching involved in ureteric bud morphogenesis 1/320 21/18722 0.303880624502876 0.432381108968968 MAGED1 1 GO:0150146 cell junction disassembly 1/320 21/18722 0.303880624502876 0.432381108968968 TGFBR1 1 GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1/320 21/18722 0.303880624502876 0.432381108968968 HSPA1A 1 GO:1902644 tertiary alcohol metabolic process 1/320 21/18722 0.303880624502876 0.432381108968968 CYP11A1 1 GO:2000774 positive regulation of cellular senescence 1/320 21/18722 0.303880624502876 0.432381108968968 B2M 1 GO:0061025 membrane fusion 4/320 163/18722 0.304309495941674 0.4328422847611 CORO1A/ANXA1/CTSL/SPESP1 4 GO:0044106 cellular amine metabolic process 3/320 113/18722 0.304528655669836 0.432856004550314 ITGB2/OAZ1/AZIN1 3 GO:0044344 cellular response to fibroblast growth factor stimulus 3/320 113/18722 0.304528655669836 0.432856004550314 ZFP36/ZFP36L2/CTNNB1 3 GO:0008202 steroid metabolic process 7/320 319/18722 0.304985955142631 0.433195983610074 TSPO/CYP11A1/CYP19A1/SLC27A2/DHCR24/NPC2/LRP2 7 GO:0003170 heart valve development 2/320 65/18722 0.30539687808716 0.433195983610074 TNFRSF1B/SOX4 2 GO:0006487 protein N-linked glycosylation 2/320 65/18722 0.30539687808716 0.433195983610074 UBE2J1/TUSC3 2 GO:0033692 cellular polysaccharide biosynthetic process 2/320 65/18722 0.30539687808716 0.433195983610074 IGF2/UGP2 2 GO:0045682 regulation of epidermis development 2/320 65/18722 0.30539687808716 0.433195983610074 ZFP36/EZH2 2 GO:1902475 L-alpha-amino acid transmembrane transport 2/320 65/18722 0.30539687808716 0.433195983610074 ITGB1/SLC43A2 2 GO:0009416 response to light stimulus 7/320 320/18722 0.307702969001246 0.436317319119132 GPX1/RDH13/BHLHE40/ITGB1/PARP1/PBK/CARD16 7 GO:0007041 lysosomal transport 3/320 114/18722 0.309204304135227 0.437845162675379 LAPTM5/PSAP/HSPA1A 3 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 3/320 114/18722 0.309204304135227 0.437845162675379 ZEB2/TGFBR1/PARP1 3 GO:1901800 positive regulation of proteasomal protein catabolic process 3/320 114/18722 0.309204304135227 0.437845162675379 CAV1/DDA1/HSPA1A 3 GO:1904892 regulation of receptor signaling pathway via STAT 3/320 114/18722 0.309204304135227 0.437845162675379 PTPRC/CAV1/PARP14 3 GO:0006303 double-strand break repair via nonhomologous end joining 2/320 66/18722 0.311708635641472 0.440938063153222 HMGB1/DEK 2 GO:0050922 negative regulation of chemotaxis 2/320 66/18722 0.311708635641472 0.440938063153222 AIF1/SEMA6D 2 GO:2000573 positive regulation of DNA biosynthetic process 2/320 66/18722 0.311708635641472 0.440938063153222 RFC3/CTNNB1 2 GO:0071772 response to BMP 4/320 165/18722 0.31201214976156 0.440977807410793 HTRA1/FBN1/LRP2/PDCD4 4 GO:0071773 cellular response to BMP stimulus 4/320 165/18722 0.31201214976156 0.440977807410793 HTRA1/FBN1/LRP2/PDCD4 4 GO:0000077 DNA damage checkpoint signaling 3/320 115/18722 0.313882371082801 0.440977807410793 PPP1R10/CDK1/SOX4 3 GO:0002089 lens morphogenesis in camera-type eye 1/320 22/18722 0.315792190737787 0.440977807410793 CTNNB1 1 GO:0002320 lymphoid progenitor cell differentiation 1/320 22/18722 0.315792190737787 0.440977807410793 SOX4 1 GO:0006359 regulation of transcription by RNA polymerase III 1/320 22/18722 0.315792190737787 0.440977807410793 ICE1 1 GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization 1/320 22/18722 0.315792190737787 0.440977807410793 SPESP1 1 GO:0007398 ectoderm development 1/320 22/18722 0.315792190737787 0.440977807410793 CTNNB1 1 GO:0008211 glucocorticoid metabolic process 1/320 22/18722 0.315792190737787 0.440977807410793 CYP11A1 1 GO:0009220 pyrimidine ribonucleotide biosynthetic process 1/320 22/18722 0.315792190737787 0.440977807410793 UPP1 1 GO:0010310 regulation of hydrogen peroxide metabolic process 1/320 22/18722 0.315792190737787 0.440977807410793 SOD2 1 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 1/320 22/18722 0.315792190737787 0.440977807410793 GSTO1 1 GO:0019400 alditol metabolic process 1/320 22/18722 0.315792190737787 0.440977807410793 TPI1 1 GO:0021854 hypothalamus development 1/320 22/18722 0.315792190737787 0.440977807410793 NRP2 1 GO:0022616 DNA strand elongation 1/320 22/18722 0.315792190737787 0.440977807410793 RFC3 1 GO:0031281 positive regulation of cyclase activity 1/320 22/18722 0.315792190737787 0.440977807410793 TIMP2 1 GO:0032402 melanosome transport 1/320 22/18722 0.315792190737787 0.440977807410793 RAB17 1 GO:0032693 negative regulation of interleukin-10 production 1/320 22/18722 0.315792190737787 0.440977807410793 TYROBP 1 GO:0032891 negative regulation of organic acid transport 1/320 22/18722 0.315792190737787 0.440977807410793 SLC43A2 1 GO:0034629 cellular protein-containing complex localization 1/320 22/18722 0.315792190737787 0.440977807410793 EZR 1 GO:0035561 regulation of chromatin binding 1/320 22/18722 0.315792190737787 0.440977807410793 GMNN 1 GO:0035584 calcium-mediated signaling using intracellular calcium source 1/320 22/18722 0.315792190737787 0.440977807410793 PTPRC 1 GO:0045624 positive regulation of T-helper cell differentiation 1/320 22/18722 0.315792190737787 0.440977807410793 ANXA1 1 GO:0045663 positive regulation of myoblast differentiation 1/320 22/18722 0.315792190737787 0.440977807410793 IGFBP3 1 GO:0046058 cAMP metabolic process 1/320 22/18722 0.315792190737787 0.440977807410793 PDE4B 1 GO:0046628 positive regulation of insulin receptor signaling pathway 1/320 22/18722 0.315792190737787 0.440977807410793 IGF2 1 GO:0048026 positive regulation of mRNA splicing, via spliceosome 1/320 22/18722 0.315792190737787 0.440977807410793 TRA2B 1 GO:0051151 negative regulation of smooth muscle cell differentiation 1/320 22/18722 0.315792190737787 0.440977807410793 PDCD4 1 GO:0051412 response to corticosterone 1/320 22/18722 0.315792190737787 0.440977807410793 ATP2B1 1 GO:0055093 response to hyperoxia 1/320 22/18722 0.315792190737787 0.440977807410793 CAV1 1 GO:0061042 vascular wound healing 1/320 22/18722 0.315792190737787 0.440977807410793 CXCR4 1 GO:0071359 cellular response to dsRNA 1/320 22/18722 0.315792190737787 0.440977807410793 CAV1 1 GO:0072574 hepatocyte proliferation 1/320 22/18722 0.315792190737787 0.440977807410793 CEBPB 1 GO:0072575 epithelial cell proliferation involved in liver morphogenesis 1/320 22/18722 0.315792190737787 0.440977807410793 CEBPB 1 GO:0090280 positive regulation of calcium ion import 1/320 22/18722 0.315792190737787 0.440977807410793 CCL3 1 GO:1900543 negative regulation of purine nucleotide metabolic process 1/320 22/18722 0.315792190737787 0.440977807410793 PARP1 1 GO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1/320 22/18722 0.315792190737787 0.440977807410793 HMOX1 1 GO:2000773 negative regulation of cellular senescence 1/320 22/18722 0.315792190737787 0.440977807410793 NAMPT 1 GO:0032890 regulation of organic acid transport 2/320 67/18722 0.318008255200487 0.443772411512466 ITGB1/SLC43A2 2 GO:0042130 negative regulation of T cell proliferation 2/320 67/18722 0.318008255200487 0.443772411512466 HLA-DRB1/CEBPB 2 GO:0006720 isoprenoid metabolic process 3/320 116/18722 0.318562126733891 0.444095380453589 RDH13/NPC2/LRP2 3 GO:0007006 mitochondrial membrane organization 3/320 116/18722 0.318562126733891 0.444095380453589 BNIP3L/PMAIP1/HSPA1A 3 GO:0098732 macromolecule deacylation 3/320 116/18722 0.318562126733891 0.444095380453589 FLNA/MORF4L2/PPT1 3 GO:0007254 JNK cascade 4/320 167/18722 0.31973291344175 0.445577200115114 NCF1/CDC42/HMGB1/PDCD4 4 GO:0051962 positive regulation of nervous system development 6/320 272/18722 0.32171877879493 0.448193524605748 TNFRSF1B/TSPO/CXCR4/FN1/LRP2/CTNNB1 6 GO:0030301 cholesterol transport 3/320 117/18722 0.323242853158645 0.450013298265337 TSPO/CAV1/NPC2 3 GO:1903828 negative regulation of cellular protein localization 3/320 117/18722 0.323242853158645 0.450013298265337 GBP1/UBE2J1/MAGED1 3 GO:1902806 regulation of cell cycle G1/S phase transition 4/320 168/18722 0.32359901597175 0.450027373641939 AIF1/ANXA1/EZH2/SOX4 4 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 2/320 68/18722 0.324294310850685 0.450027373641939 PARP14/ISL1 2 GO:0061912 selective autophagy 2/320 68/18722 0.324294310850685 0.450027373641939 UBA5/VPS13C 2 GO:1901016 regulation of potassium ion transmembrane transporter activity 2/320 68/18722 0.324294310850685 0.450027373641939 CAV1/ITGB1 2 GO:1902305 regulation of sodium ion transmembrane transport 2/320 68/18722 0.324294310850685 0.450027373641939 FXYD5/FXYD3 2 GO:1904888 cranial skeletal system development 2/320 68/18722 0.324294310850685 0.450027373641939 TGFBR1/CTNNB1 2 GO:0018394 peptidyl-lysine acetylation 4/320 169/18722 0.327468369078417 0.450027373641939 MBD3/ISL1/MORF4L2/SOX4 4 GO:0000966 RNA 5'-end processing 1/320 23/18722 0.327500559666338 0.450027373641939 SSB 1 GO:0001759 organ induction 1/320 23/18722 0.327500559666338 0.450027373641939 CTNNB1 1 GO:0002052 positive regulation of neuroblast proliferation 1/320 23/18722 0.327500559666338 0.450027373641939 CTNNB1 1 GO:0002082 regulation of oxidative phosphorylation 1/320 23/18722 0.327500559666338 0.450027373641939 RHOA 1 GO:0006622 protein targeting to lysosome 1/320 23/18722 0.327500559666338 0.450027373641939 LAPTM5 1 GO:0009162 deoxyribonucleoside monophosphate metabolic process 1/320 23/18722 0.327500559666338 0.450027373641939 UPP1 1 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 1/320 23/18722 0.327500559666338 0.450027373641939 CARD16 1 GO:0021871 forebrain regionalization 1/320 23/18722 0.327500559666338 0.450027373641939 TRA2B 1 GO:0021884 forebrain neuron development 1/320 23/18722 0.327500559666338 0.450027373641939 NRP2 1 GO:0030325 adrenal gland development 1/320 23/18722 0.327500559666338 0.450027373641939 TSPO 1 GO:0032401 establishment of melanosome localization 1/320 23/18722 0.327500559666338 0.450027373641939 RAB17 1 GO:0035994 response to muscle stretch 1/320 23/18722 0.327500559666338 0.450027373641939 CTNNB1 1 GO:0042438 melanin biosynthetic process 1/320 23/18722 0.327500559666338 0.450027373641939 ZEB2 1 GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment 1/320 23/18722 0.327500559666338 0.450027373641939 CTSL 1 GO:0045932 negative regulation of muscle contraction 1/320 23/18722 0.327500559666338 0.450027373641939 SRI 1 GO:0045980 negative regulation of nucleotide metabolic process 1/320 23/18722 0.327500559666338 0.450027373641939 PARP1 1 GO:0050765 negative regulation of phagocytosis 1/320 23/18722 0.327500559666338 0.450027373641939 HMGB1 1 GO:0051131 chaperone-mediated protein complex assembly 1/320 23/18722 0.327500559666338 0.450027373641939 HSPA1A 1 GO:0051349 positive regulation of lyase activity 1/320 23/18722 0.327500559666338 0.450027373641939 TIMP2 1 GO:0051457 maintenance of protein location in nucleus 1/320 23/18722 0.327500559666338 0.450027373641939 SYNE1 1 GO:0051590 positive regulation of neurotransmitter transport 1/320 23/18722 0.327500559666338 0.450027373641939 ITGB1 1 GO:0051904 pigment granule transport 1/320 23/18722 0.327500559666338 0.450027373641939 RAB17 1 GO:0060353 regulation of cell adhesion molecule production 1/320 23/18722 0.327500559666338 0.450027373641939 CAV1 1 GO:0060384 innervation 1/320 23/18722 0.327500559666338 0.450027373641939 ISL1 1 GO:0060487 lung epithelial cell differentiation 1/320 23/18722 0.327500559666338 0.450027373641939 KLF2 1 GO:0071305 cellular response to vitamin D 1/320 23/18722 0.327500559666338 0.450027373641939 ATP2B1 1 GO:0071514 genetic imprinting 1/320 23/18722 0.327500559666338 0.450027373641939 IGF2 1 GO:0072576 liver morphogenesis 1/320 23/18722 0.327500559666338 0.450027373641939 CEBPB 1 GO:0072677 eosinophil migration 1/320 23/18722 0.327500559666338 0.450027373641939 CCL3 1 GO:1902410 mitotic cytokinetic process 1/320 23/18722 0.327500559666338 0.450027373641939 RHOA 1 GO:1903306 negative regulation of regulated secretory pathway 1/320 23/18722 0.327500559666338 0.450027373641939 HMOX1 1 GO:2000810 regulation of bicellular tight junction assembly 1/320 23/18722 0.327500559666338 0.450027373641939 GJA1 1 GO:0009308 amine metabolic process 3/320 118/18722 0.327923844293865 0.450309513001745 ITGB2/OAZ1/AZIN1 3 GO:1903313 positive regulation of mRNA metabolic process 3/320 118/18722 0.327923844293865 0.450309513001745 ZFP36/ZFP36L2/TRA2B 3 GO:0010498 proteasomal protein catabolic process 10/320 490/18722 0.329060231604133 0.451719892687135 PSMB9/CAV1/GPX1/PMAIP1/DDA1/UBE2J1/PSMD1/HSPA1A/PBK/CTNNB1 10 GO:0030111 regulation of Wnt signaling pathway 7/320 328/18722 0.32959951963084 0.452309935275534 ZEB2/CAV1/WLS/ISL1/PLPP3/SOX4/LGR5 7 GO:0010611 regulation of cardiac muscle hypertrophy 2/320 69/18722 0.33056542865771 0.452733295065846 TNFRSF1B/PARP1 2 GO:0015807 L-amino acid transport 2/320 69/18722 0.33056542865771 0.452733295065846 ITGB1/SLC43A2 2 GO:0033344 cholesterol efflux 2/320 69/18722 0.33056542865771 0.452733295065846 CAV1/NPC2 2 GO:0045669 positive regulation of osteoblast differentiation 2/320 69/18722 0.33056542865771 0.452733295065846 CTNNB1/CEBPB 2 GO:0060193 positive regulation of lipase activity 2/320 69/18722 0.33056542865771 0.452733295065846 FLT1/RHOA 2 GO:1904377 positive regulation of protein localization to cell periphery 2/320 69/18722 0.33056542865771 0.452733295065846 EZR/ITGB1 2 GO:0046890 regulation of lipid biosynthetic process 4/320 171/18722 0.335215161162039 0.458372369217688 TSPO/ANXA1/CD74/IDH1 4 GO:0022412 cellular process involved in reproduction in multicellular organism 8/320 384/18722 0.335271146157503 0.458372369217688 DYNLL1/ITGB1/TGFBR1/UBE2J1/CTNNB1/LGR5/TOP2A/SPESP1 8 GO:0003407 neural retina development 2/320 70/18722 0.336820285315709 0.458372369217688 RDH13/ATP2B1 2 GO:0045123 cellular extravasation 2/320 70/18722 0.336820285315709 0.458372369217688 CD99/ITGB1 2 GO:0070830 bicellular tight junction assembly 2/320 70/18722 0.336820285315709 0.458372369217688 MTDH/GJA1 2 GO:0048593 camera-type eye morphogenesis 3/320 120/18722 0.337283855830653 0.458372369217688 RDH13/C12orf57/CTNNB1 3 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/320 24/18722 0.339009186914147 0.458372369217688 RPS21 1 GO:0001702 gastrulation with mouth forming second 1/320 24/18722 0.339009186914147 0.458372369217688 CTNNB1 1 GO:0001779 natural killer cell differentiation 1/320 24/18722 0.339009186914147 0.458372369217688 PTPRC 1 GO:0002438 acute inflammatory response to antigenic stimulus 1/320 24/18722 0.339009186914147 0.458372369217688 HLA-E 1 GO:0002922 positive regulation of humoral immune response 1/320 24/18722 0.339009186914147 0.458372369217688 PTPRC 1 GO:0003181 atrioventricular valve morphogenesis 1/320 24/18722 0.339009186914147 0.458372369217688 SOX4 1 GO:0006582 melanin metabolic process 1/320 24/18722 0.339009186914147 0.458372369217688 ZEB2 1 GO:0006817 phosphate ion transport 1/320 24/18722 0.339009186914147 0.458372369217688 CEBPB 1 GO:0009219 pyrimidine deoxyribonucleotide metabolic process 1/320 24/18722 0.339009186914147 0.458372369217688 UPP1 1 GO:0010155 regulation of proton transport 1/320 24/18722 0.339009186914147 0.458372369217688 TMSB4X 1 GO:0016048 detection of temperature stimulus 1/320 24/18722 0.339009186914147 0.458372369217688 CXCR4 1 GO:0016486 peptide hormone processing 1/320 24/18722 0.339009186914147 0.458372369217688 CTSL 1 GO:0021801 cerebral cortex radial glia-guided migration 1/320 24/18722 0.339009186914147 0.458372369217688 CTNNB1 1 GO:0022030 telencephalon glial cell migration 1/320 24/18722 0.339009186914147 0.458372369217688 CTNNB1 1 GO:0033032 regulation of myeloid cell apoptotic process 1/320 24/18722 0.339009186914147 0.458372369217688 ANXA1 1 GO:0038095 Fc-epsilon receptor signaling pathway 1/320 24/18722 0.339009186914147 0.458372369217688 FCER1G 1 GO:0043302 positive regulation of leukocyte degranulation 1/320 24/18722 0.339009186914147 0.458372369217688 ITGB2 1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 1/320 24/18722 0.339009186914147 0.458372369217688 IGFBP3 1 GO:0044321 response to leptin 1/320 24/18722 0.339009186914147 0.458372369217688 LRP2 1 GO:0050855 regulation of B cell receptor signaling pathway 1/320 24/18722 0.339009186914147 0.458372369217688 SLC39A10 1 GO:0051123 RNA polymerase II preinitiation complex assembly 1/320 24/18722 0.339009186914147 0.458372369217688 HMGB1 1 GO:0051647 nucleus localization 1/320 24/18722 0.339009186914147 0.458372369217688 CDC42 1 GO:0051905 establishment of pigment granule localization 1/320 24/18722 0.339009186914147 0.458372369217688 RAB17 1 GO:0060561 apoptotic process involved in morphogenesis 1/320 24/18722 0.339009186914147 0.458372369217688 TNFRSF1B 1 GO:0060571 morphogenesis of an epithelial fold 1/320 24/18722 0.339009186914147 0.458372369217688 CTNNB1 1 GO:0070841 inclusion body assembly 1/320 24/18722 0.339009186914147 0.458372369217688 HSPA1A 1 GO:0071577 zinc ion transmembrane transport 1/320 24/18722 0.339009186914147 0.458372369217688 SLC39A10 1 GO:0090023 positive regulation of neutrophil chemotaxis 1/320 24/18722 0.339009186914147 0.458372369217688 CD74 1 GO:0090343 positive regulation of cell aging 1/320 24/18722 0.339009186914147 0.458372369217688 B2M 1 GO:1903077 negative regulation of protein localization to plasma membrane 1/320 24/18722 0.339009186914147 0.458372369217688 GBP1 1 GO:1903861 positive regulation of dendrite extension 1/320 24/18722 0.339009186914147 0.458372369217688 CXCR4 1 GO:2000310 regulation of NMDA receptor activity 1/320 24/18722 0.339009186914147 0.458372369217688 IFNGR2 1 GO:2000353 positive regulation of endothelial cell apoptotic process 1/320 24/18722 0.339009186914147 0.458372369217688 PDCD4 1 GO:0006364 rRNA processing 5/320 225/18722 0.340585230082938 0.460352689140563 RPS27/RPS21/RPS17/RPS28/PA2G4 5 GO:0010469 regulation of signaling receptor activity 4/320 173/18722 0.342969998587244 0.463088543420777 NCF1/PHLDA2/ITGB1/IFNGR2 4 GO:0033555 multicellular organismal response to stress 2/320 71/18722 0.343057606827444 0.463088543420777 TSPO/GJA1 2 GO:0043550 regulation of lipid kinase activity 2/320 71/18722 0.343057606827444 0.463088543420777 CDC42/FLT1 2 GO:0072078 nephron tubule morphogenesis 2/320 71/18722 0.343057606827444 0.463088543420777 MAGED1/CTNNB1 2 GO:0021700 developmental maturation 6/320 280/18722 0.345875571135252 0.466493171789164 KLF2/CD63/PFN1/SNX10/RHOA/CTNNB1 6 GO:0031109 microtubule polymerization or depolymerization 3/320 122/18722 0.346636750383875 0.466493171789164 CCSAP/STMN1/HSPA1A 3 GO:0000271 polysaccharide biosynthetic process 2/320 72/18722 0.349276167214477 0.466493171789164 IGF2/UGP2 2 GO:0001736 establishment of planar polarity 2/320 72/18722 0.349276167214477 0.466493171789164 CDC42/RHOA 2 GO:0002534 cytokine production involved in inflammatory response 2/320 72/18722 0.349276167214477 0.466493171789164 EZH2/PDCD4 2 GO:0007164 establishment of tissue polarity 2/320 72/18722 0.349276167214477 0.466493171789164 CDC42/RHOA 2 GO:0014743 regulation of muscle hypertrophy 2/320 72/18722 0.349276167214477 0.466493171789164 TNFRSF1B/PARP1 2 GO:0035567 non-canonical Wnt signaling pathway 2/320 72/18722 0.349276167214477 0.466493171789164 CDC42/RHOA 2 GO:0071479 cellular response to ionizing radiation 2/320 72/18722 0.349276167214477 0.466493171789164 CYBA/NAMPT 2 GO:1900015 regulation of cytokine production involved in inflammatory response 2/320 72/18722 0.349276167214477 0.466493171789164 EZH2/PDCD4 2 GO:0010447 response to acidic pH 1/320 25/18722 0.350321469521243 0.466493171789164 CTSS 1 GO:0010560 positive regulation of glycoprotein biosynthetic process 1/320 25/18722 0.350321469521243 0.466493171789164 CTNNB1 1 GO:0010842 retina layer formation 1/320 25/18722 0.350321469521243 0.466493171789164 RDH13 1 GO:0015012 heparan sulfate proteoglycan biosynthetic process 1/320 25/18722 0.350321469521243 0.466493171789164 CTNNB1 1 GO:0015874 norepinephrine transport 1/320 25/18722 0.350321469521243 0.466493171789164 ACTB 1 GO:0030318 melanocyte differentiation 1/320 25/18722 0.350321469521243 0.466493171789164 ZEB2 1 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 1/320 25/18722 0.350321469521243 0.466493171789164 CARD16 1 GO:0032400 melanosome localization 1/320 25/18722 0.350321469521243 0.466493171789164 RAB17 1 GO:0033233 regulation of protein sumoylation 1/320 25/18722 0.350321469521243 0.466493171789164 CTNNB1 1 GO:0035902 response to immobilization stress 1/320 25/18722 0.350321469521243 0.466493171789164 SOD2 1 GO:0042832 defense response to protozoan 1/320 25/18722 0.350321469521243 0.466493171789164 GBP2 1 GO:0044550 secondary metabolite biosynthetic process 1/320 25/18722 0.350321469521243 0.466493171789164 ZEB2 1 GO:0045822 negative regulation of heart contraction 1/320 25/18722 0.350321469521243 0.466493171789164 SRI 1 GO:0046039 GTP metabolic process 1/320 25/18722 0.350321469521243 0.466493171789164 RHOA 1 GO:0046949 fatty-acyl-CoA biosynthetic process 1/320 25/18722 0.350321469521243 0.466493171789164 PPT1 1 GO:0050927 positive regulation of positive chemotaxis 1/320 25/18722 0.350321469521243 0.466493171789164 PGF 1 GO:0050951 sensory perception of temperature stimulus 1/320 25/18722 0.350321469521243 0.466493171789164 CXCR4 1 GO:0051307 meiotic chromosome separation 1/320 25/18722 0.350321469521243 0.466493171789164 TOP2A 1 GO:0051450 myoblast proliferation 1/320 25/18722 0.350321469521243 0.466493171789164 GPX1 1 GO:0060074 synapse maturation 1/320 25/18722 0.350321469521243 0.466493171789164 PFN1 1 GO:0062149 detection of stimulus involved in sensory perception of pain 1/320 25/18722 0.350321469521243 0.466493171789164 CXCR4 1 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 1/320 25/18722 0.350321469521243 0.466493171789164 HSPA1A 1 GO:0071459 protein localization to chromosome, centromeric region 1/320 25/18722 0.350321469521243 0.466493171789164 CDK1 1 GO:0072207 metanephric epithelium development 1/320 25/18722 0.350321469521243 0.466493171789164 STAT1 1 GO:0086013 membrane repolarization during cardiac muscle cell action potential 1/320 25/18722 0.350321469521243 0.466493171789164 FLNA 1 GO:0090382 phagosome maturation 1/320 25/18722 0.350321469521243 0.466493171789164 CORO1A 1 GO:0140448 signaling receptor ligand precursor processing 1/320 25/18722 0.350321469521243 0.466493171789164 CTSL 1 GO:1900078 positive regulation of cellular response to insulin stimulus 1/320 25/18722 0.350321469521243 0.466493171789164 IGF2 1 GO:1901623 regulation of lymphocyte chemotaxis 1/320 25/18722 0.350321469521243 0.466493171789164 CCL3 1 GO:1903792 negative regulation of anion transport 1/320 25/18722 0.350321469521243 0.466493171789164 SLC43A2 1 GO:1904753 negative regulation of vascular associated smooth muscle cell migration 1/320 25/18722 0.350321469521243 0.466493171789164 RHOA 1 GO:1905563 negative regulation of vascular endothelial cell proliferation 1/320 25/18722 0.350321469521243 0.466493171789164 FLT1 1 GO:0006631 fatty acid metabolic process 8/320 390/18722 0.350657330213495 0.466789976946572 CROT/CYP2J2/CAV1/GPX1/ANXA1/CD74/SLC27A2/GPX4 8 GO:0031570 DNA integrity checkpoint signaling 3/320 123/18722 0.351308889778986 0.467356192069146 PPP1R10/CDK1/SOX4 3 GO:0071482 cellular response to light stimulus 3/320 123/18722 0.351308889778986 0.467356192069146 PARP1/PBK/CARD16 3 GO:0042058 regulation of epidermal growth factor receptor signaling pathway 2/320 73/18722 0.355474787256833 0.472441885154465 NCF1/PLAUR 2 GO:0061035 regulation of cartilage development 2/320 73/18722 0.355474787256833 0.472441885154465 TGFBR1/CTNNB1 2 GO:1904427 positive regulation of calcium ion transmembrane transport 2/320 73/18722 0.355474787256833 0.472441885154465 SRI/GSTO1 2 GO:0030324 lung development 4/320 177/18722 0.358490977774269 0.475476971131477 KLF2/CDC42/HMGB1/CTNNB1 4 GO:0018210 peptidyl-threonine modification 3/320 125/18722 0.360641378324901 0.475476971131477 GALNT11/TGFBR1/CDK1 3 GO:0070585 protein localization to mitochondrion 3/320 125/18722 0.360641378324901 0.475476971131477 TSPO/ISG15/BNIP3L 3 GO:0001562 response to protozoan 1/320 26/18722 0.361440746932228 0.475476971131477 GBP2 1 GO:0002026 regulation of the force of heart contraction 1/320 26/18722 0.361440746932228 0.475476971131477 CAV1 1 GO:0002092 positive regulation of receptor internalization 1/320 26/18722 0.361440746932228 0.475476971131477 CD63 1 GO:0002710 negative regulation of T cell mediated immunity 1/320 26/18722 0.361440746932228 0.475476971131477 PTPRC 1 GO:0003416 endochondral bone growth 1/320 26/18722 0.361440746932228 0.475476971131477 ANXA6 1 GO:0006706 steroid catabolic process 1/320 26/18722 0.361440746932228 0.475476971131477 CYP19A1 1 GO:0009435 NAD biosynthetic process 1/320 26/18722 0.361440746932228 0.475476971131477 NAMPT 1 GO:0010875 positive regulation of cholesterol efflux 1/320 26/18722 0.361440746932228 0.475476971131477 CAV1 1 GO:0021952 central nervous system projection neuron axonogenesis 1/320 26/18722 0.361440746932228 0.475476971131477 C12orf57 1 GO:0034114 regulation of heterotypic cell-cell adhesion 1/320 26/18722 0.361440746932228 0.475476971131477 MYADM 1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated 1/320 26/18722 0.361440746932228 0.475476971131477 ARMCX3 1 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 1/320 26/18722 0.361440746932228 0.475476971131477 HSPA1A 1 GO:0043094 cellular metabolic compound salvage 1/320 26/18722 0.361440746932228 0.475476971131477 UPP1 1 GO:0045026 plasma membrane fusion 1/320 26/18722 0.361440746932228 0.475476971131477 SPESP1 1 GO:0045672 positive regulation of osteoclast differentiation 1/320 26/18722 0.361440746932228 0.475476971131477 TYROBP 1 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity 1/320 26/18722 0.361440746932228 0.475476971131477 HLA-E 1 GO:0047497 mitochondrion transport along microtubule 1/320 26/18722 0.361440746932228 0.475476971131477 ARMCX3 1 GO:0048843 negative regulation of axon extension involved in axon guidance 1/320 26/18722 0.361440746932228 0.475476971131477 SEMA6D 1 GO:0050926 regulation of positive chemotaxis 1/320 26/18722 0.361440746932228 0.475476971131477 PGF 1 GO:0051560 mitochondrial calcium ion homeostasis 1/320 26/18722 0.361440746932228 0.475476971131477 ANXA6 1 GO:0051875 pigment granule localization 1/320 26/18722 0.361440746932228 0.475476971131477 RAB17 1 GO:0060295 regulation of cilium movement involved in cell motility 1/320 26/18722 0.361440746932228 0.475476971131477 CCSAP 1 GO:0060352 cell adhesion molecule production 1/320 26/18722 0.361440746932228 0.475476971131477 CAV1 1 GO:0060669 embryonic placenta morphogenesis 1/320 26/18722 0.361440746932228 0.475476971131477 IGF2 1 GO:1902019 regulation of cilium-dependent cell motility 1/320 26/18722 0.361440746932228 0.475476971131477 CCSAP 1 GO:1903523 negative regulation of blood circulation 1/320 26/18722 0.361440746932228 0.475476971131477 SRI 1 GO:1904376 negative regulation of protein localization to cell periphery 1/320 26/18722 0.361440746932228 0.475476971131477 GBP1 1 GO:1905523 positive regulation of macrophage migration 1/320 26/18722 0.361440746932228 0.475476971131477 CCL3 1 GO:2000108 positive regulation of leukocyte apoptotic process 1/320 26/18722 0.361440746932228 0.475476971131477 ANXA1 1 GO:0006635 fatty acid beta-oxidation 2/320 74/18722 0.361652333261489 0.475603895937769 CROT/SLC27A2 2 GO:0048015 phosphatidylinositol-mediated signaling 4/320 178/18722 0.362371294551011 0.47639776935564 NCF1/FN1/EZR/FLT1 4 GO:0032874 positive regulation of stress-activated MAPK cascade 3/320 126/18722 0.365300493050514 0.48009594061219 NCF1/CDC42/HMGB1 3 GO:1901991 negative regulation of mitotic cell cycle phase transition 4/320 179/18722 0.366250874770642 0.481191928315514 ZFP36L2/CDK1/EZH2/SOX4 4 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 5/320 233/18722 0.367660554288197 0.482470311723724 FLNA/ARRDC3/PSAP/PDE4B/LGR5 5 GO:0006094 gluconeogenesis 2/320 75/18722 0.367807715859083 0.482470311723724 TPI1/PGK1 2 GO:0036465 synaptic vesicle recycling 2/320 75/18722 0.367807715859083 0.482470311723724 ACTG1/ACTB 2 GO:0051453 regulation of intracellular pH 2/320 75/18722 0.367807715859083 0.482470311723724 CLIC4/PPT1 2 GO:1903363 negative regulation of cellular protein catabolic process 2/320 75/18722 0.367807715859083 0.482470311723724 RPL23/PBK 2 GO:1903311 regulation of mRNA metabolic process 6/320 288/18722 0.370196742109402 0.483543082256143 VIM/ZFP36/FUS/ZFP36L2/TRA2B/YBX3 6 GO:0000469 cleavage involved in rRNA processing 1/320 27/18722 0.37237030196976 0.483543082256143 RPS21 1 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 1/320 27/18722 0.37237030196976 0.483543082256143 PTPRC 1 GO:0002825 regulation of T-helper 1 type immune response 1/320 27/18722 0.37237030196976 0.483543082256143 ANXA1 1 GO:0003171 atrioventricular valve development 1/320 27/18722 0.37237030196976 0.483543082256143 SOX4 1 GO:0003272 endocardial cushion formation 1/320 27/18722 0.37237030196976 0.483543082256143 TGFBR1 1 GO:0006783 heme biosynthetic process 1/320 27/18722 0.37237030196976 0.483543082256143 TSPO 1 GO:0008053 mitochondrial fusion 1/320 27/18722 0.37237030196976 0.483543082256143 TFRC 1 GO:0009651 response to salt stress 1/320 27/18722 0.37237030196976 0.483543082256143 EFHD1 1 GO:0010528 regulation of transposition 1/320 27/18722 0.37237030196976 0.483543082256143 APOBEC3A 1 GO:0010529 negative regulation of transposition 1/320 27/18722 0.37237030196976 0.483543082256143 APOBEC3A 1 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 1/320 27/18722 0.37237030196976 0.483543082256143 GSTO1 1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 1/320 27/18722 0.37237030196976 0.483543082256143 CDK1 1 GO:0015813 L-glutamate transmembrane transport 1/320 27/18722 0.37237030196976 0.483543082256143 ITGB1 1 GO:0018126 protein hydroxylation 1/320 27/18722 0.37237030196976 0.483543082256143 P4HA1 1 GO:0032781 positive regulation of ATPase activity 1/320 27/18722 0.37237030196976 0.483543082256143 PFN1 1 GO:0032786 positive regulation of DNA-templated transcription, elongation 1/320 27/18722 0.37237030196976 0.483543082256143 CTNNB1 1 GO:0032967 positive regulation of collagen biosynthetic process 1/320 27/18722 0.37237030196976 0.483543082256143 VIM 1 GO:0033688 regulation of osteoblast proliferation 1/320 27/18722 0.37237030196976 0.483543082256143 RHOA 1 GO:0034143 regulation of toll-like receptor 4 signaling pathway 1/320 27/18722 0.37237030196976 0.483543082256143 HMGB1 1 GO:0035116 embryonic hindlimb morphogenesis 1/320 27/18722 0.37237030196976 0.483543082256143 CTNNB1 1 GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 1/320 27/18722 0.37237030196976 0.483543082256143 PTPRC 1 GO:0042403 thyroid hormone metabolic process 1/320 27/18722 0.37237030196976 0.483543082256143 CTSB 1 GO:0046174 polyol catabolic process 1/320 27/18722 0.37237030196976 0.483543082256143 TPI1 1 GO:0048520 positive regulation of behavior 1/320 27/18722 0.37237030196976 0.483543082256143 GJA1 1 GO:0048873 homeostasis of number of cells within a tissue 1/320 27/18722 0.37237030196976 0.483543082256143 CORO1A 1 GO:0051953 negative regulation of amine transport 1/320 27/18722 0.37237030196976 0.483543082256143 SLC43A2 1 GO:0070861 regulation of protein exit from endoplasmic reticulum 1/320 27/18722 0.37237030196976 0.483543082256143 UBE2J1 1 GO:0071624 positive regulation of granulocyte chemotaxis 1/320 27/18722 0.37237030196976 0.483543082256143 CD74 1 GO:1900746 regulation of vascular endothelial growth factor signaling pathway 1/320 27/18722 0.37237030196976 0.483543082256143 CD63 1 GO:1903859 regulation of dendrite extension 1/320 27/18722 0.37237030196976 0.483543082256143 CXCR4 1 GO:1904357 negative regulation of telomere maintenance via telomere lengthening 1/320 27/18722 0.37237030196976 0.483543082256143 PARP1 1 GO:0021536 diencephalon development 2/320 76/18722 0.373939888828249 0.48505780189414 NRP2/ISL1 2 GO:0140029 exocytic process 2/320 76/18722 0.373939888828249 0.48505780189414 PLEK/STXBP2 2 GO:0140115 export across plasma membrane 2/320 76/18722 0.373939888828249 0.48505780189414 ATP2B1/GJA1 2 GO:0030323 respiratory tube development 4/320 181/18722 0.374006330308502 0.48505780189414 KLF2/CDC42/HMGB1/CTNNB1 4 GO:0035303 regulation of dephosphorylation 3/320 128/18722 0.374601465317933 0.485524860317973 PTPRC/PLEK/SLC39A10 3 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 3/320 128/18722 0.374601465317933 0.485524860317973 NCF1/CDC42/HMGB1 3 GO:0071103 DNA conformation change 6/320 290/18722 0.376291015718288 0.487561767622442 ANXA1/HMGB3/HMGB1/CDK1/RFC3/TOP2A 6 GO:0016072 rRNA metabolic process 5/320 236/18722 0.377828416999329 0.4893156474254 RPS27/RPS21/RPS17/RPS28/PA2G4 5 GO:0048017 inositol lipid-mediated signaling 4/320 182/18722 0.377881469248415 0.4893156474254 NCF1/FN1/EZR/FLT1 4 GO:0007093 mitotic cell cycle checkpoint signaling 3/320 129/18722 0.379242158625613 0.490769996693088 PPP1R10/CDK1/SOX4 3 GO:0007498 mesoderm development 3/320 129/18722 0.379242158625613 0.490769996693088 WLS/ITGB1/GJA1 3 GO:0007059 chromosome segregation 7/320 346/18722 0.37958529076663 0.491060244661151 NEK6/CDC42/SPC25/MKI67/ACTR3/CTNNB1/TOP2A 7 GO:0140056 organelle localization by membrane tethering 2/320 77/18722 0.380047847946984 0.491350972377015 PLEK/STXBP2 2 GO:1901983 regulation of protein acetylation 2/320 77/18722 0.380047847946984 0.491350972377015 ISL1/SOX4 2 GO:1901617 organic hydroxy compound biosynthetic process 5/320 237/18722 0.381217415171434 0.49192803322653 PLEK/ZEB2/SLC27A2/ISYNA1/DHCR24 5 GO:0000423 mitophagy 1/320 28/18722 0.38311336179162 0.49192803322653 VPS13C 1 GO:0002675 positive regulation of acute inflammatory response 1/320 28/18722 0.38311336179162 0.49192803322653 HLA-E 1 GO:0003156 regulation of animal organ formation 1/320 28/18722 0.38311336179162 0.49192803322653 CTNNB1 1 GO:0006516 glycoprotein catabolic process 1/320 28/18722 0.38311336179162 0.49192803322653 CTSL 1 GO:0006829 zinc ion transport 1/320 28/18722 0.38311336179162 0.49192803322653 SLC39A10 1 GO:0010575 positive regulation of vascular endothelial growth factor production 1/320 28/18722 0.38311336179162 0.49192803322653 ISL1 1 GO:0010714 positive regulation of collagen metabolic process 1/320 28/18722 0.38311336179162 0.49192803322653 VIM 1 GO:0010884 positive regulation of lipid storage 1/320 28/18722 0.38311336179162 0.49192803322653 PLIN2 1 GO:0030262 apoptotic nuclear changes 1/320 28/18722 0.38311336179162 0.49192803322653 TOP2A 1 GO:0032438 melanosome organization 1/320 28/18722 0.38311336179162 0.49192803322653 ZEB2 1 GO:0032801 receptor catabolic process 1/320 28/18722 0.38311336179162 0.49192803322653 LAPTM5 1 GO:0032958 inositol phosphate biosynthetic process 1/320 28/18722 0.38311336179162 0.49192803322653 PLEK 1 GO:0045686 negative regulation of glial cell differentiation 1/320 28/18722 0.38311336179162 0.49192803322653 CTNNB1 1 GO:0051503 adenine nucleotide transport 1/320 28/18722 0.38311336179162 0.49192803322653 GJA1 1 GO:0060325 face morphogenesis 1/320 28/18722 0.38311336179162 0.49192803322653 CRISPLD1 1 GO:0080111 DNA demethylation 1/320 28/18722 0.38311336179162 0.49192803322653 APOBEC3A 1 GO:0090344 negative regulation of cell aging 1/320 28/18722 0.38311336179162 0.49192803322653 NAMPT 1 GO:0099623 regulation of cardiac muscle cell membrane repolarization 1/320 28/18722 0.38311336179162 0.49192803322653 FLNA 1 GO:1903020 positive regulation of glycoprotein metabolic process 1/320 28/18722 0.38311336179162 0.49192803322653 CTNNB1 1 GO:1903671 negative regulation of sprouting angiogenesis 1/320 28/18722 0.38311336179162 0.49192803322653 KLF2 1 GO:1903779 regulation of cardiac conduction 1/320 28/18722 0.38311336179162 0.49192803322653 ATP2B1 1 GO:0015918 sterol transport 3/320 130/18722 0.383875566552378 0.492753600805973 TSPO/CAV1/NPC2 3 GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 2/320 78/18722 0.38613062987047 0.494726127945669 FLNA/PSAP 2 GO:0008306 associative learning 2/320 78/18722 0.38613062987047 0.494726127945669 ITGB1/PPT1 2 GO:0019319 hexose biosynthetic process 2/320 78/18722 0.38613062987047 0.494726127945669 TPI1/PGK1 2 GO:0032371 regulation of sterol transport 2/320 78/18722 0.38613062987047 0.494726127945669 TSPO/CAV1 2 GO:0032374 regulation of cholesterol transport 2/320 78/18722 0.38613062987047 0.494726127945669 TSPO/CAV1 2 GO:0043537 negative regulation of blood vessel endothelial cell migration 2/320 78/18722 0.38613062987047 0.494726127945669 HMGB1/RHOA 2 GO:0000723 telomere maintenance 3/320 131/18722 0.388501135884119 0.497300710493551 PARP1/PPP1R10/CTNNB1 3 GO:0006612 protein targeting to membrane 3/320 131/18722 0.388501135884119 0.497300710493551 ITGB2/NCF1/TCAF1 3 GO:0050853 B cell receptor signaling pathway 3/320 131/18722 0.388501135884119 0.497300710493551 PTPRC/MNDA/SLC39A10 3 GO:1901184 regulation of ERBB signaling pathway 2/320 79/18722 0.39218731103479 0.497600870104759 NCF1/PLAUR 2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 1/320 29/18722 0.393673098831669 0.497600870104759 ZFP36 1 GO:0001773 myeloid dendritic cell activation 1/320 29/18722 0.393673098831669 0.497600870104759 HMGB1 1 GO:0005979 regulation of glycogen biosynthetic process 1/320 29/18722 0.393673098831669 0.497600870104759 IGF2 1 GO:0006734 NADH metabolic process 1/320 29/18722 0.393673098831669 0.497600870104759 ENO1 1 GO:0007143 female meiotic nuclear division 1/320 29/18722 0.393673098831669 0.497600870104759 TOP2A 1 GO:0009218 pyrimidine ribonucleotide metabolic process 1/320 29/18722 0.393673098831669 0.497600870104759 UPP1 1 GO:0010955 negative regulation of protein processing 1/320 29/18722 0.393673098831669 0.497600870104759 CARD16 1 GO:0010962 regulation of glucan biosynthetic process 1/320 29/18722 0.393673098831669 0.497600870104759 IGF2 1 GO:0015868 purine ribonucleotide transport 1/320 29/18722 0.393673098831669 0.497600870104759 GJA1 1 GO:0019359 nicotinamide nucleotide biosynthetic process 1/320 29/18722 0.393673098831669 0.497600870104759 NAMPT 1 GO:0019363 pyridine nucleotide biosynthetic process 1/320 29/18722 0.393673098831669 0.497600870104759 NAMPT 1 GO:0021602 cranial nerve morphogenesis 1/320 29/18722 0.393673098831669 0.497600870104759 NRP2 1 GO:0022011 myelination in peripheral nervous system 1/320 29/18722 0.393673098831669 0.497600870104759 PLEC 1 GO:0030970 retrograde protein transport, ER to cytosol 1/320 29/18722 0.393673098831669 0.497600870104759 UBE2J1 1 GO:0031069 hair follicle morphogenesis 1/320 29/18722 0.393673098831669 0.497600870104759 CTNNB1 1 GO:0032292 peripheral nervous system axon ensheathment 1/320 29/18722 0.393673098831669 0.497600870104759 PLEC 1 GO:0032366 intracellular sterol transport 1/320 29/18722 0.393673098831669 0.497600870104759 NPC2 1 GO:0032367 intracellular cholesterol transport 1/320 29/18722 0.393673098831669 0.497600870104759 NPC2 1 GO:0034067 protein localization to Golgi apparatus 1/320 29/18722 0.393673098831669 0.497600870104759 VPS13C 1 GO:0034311 diol metabolic process 1/320 29/18722 0.393673098831669 0.497600870104759 PLPP3 1 GO:0035066 positive regulation of histone acetylation 1/320 29/18722 0.393673098831669 0.497600870104759 ISL1 1 GO:0042759 long-chain fatty acid biosynthetic process 1/320 29/18722 0.393673098831669 0.497600870104759 GPX4 1 GO:0043153 entrainment of circadian clock by photoperiod 1/320 29/18722 0.393673098831669 0.497600870104759 BHLHE40 1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity 1/320 29/18722 0.393673098831669 0.497600870104759 CKS2 1 GO:0048265 response to pain 1/320 29/18722 0.393673098831669 0.497600870104759 TSPO 1 GO:0048665 neuron fate specification 1/320 29/18722 0.393673098831669 0.497600870104759 ISL1 1 GO:0048679 regulation of axon regeneration 1/320 29/18722 0.393673098831669 0.497600870104759 FLNA 1 GO:0048753 pigment granule organization 1/320 29/18722 0.393673098831669 0.497600870104759 ZEB2 1 GO:0051654 establishment of mitochondrion localization 1/320 29/18722 0.393673098831669 0.497600870104759 ARMCX3 1 GO:0051873 killing by host of symbiont cells 1/320 29/18722 0.393673098831669 0.497600870104759 GAPDH 1 GO:0051883 killing of cells in other organism involved in symbiotic interaction 1/320 29/18722 0.393673098831669 0.497600870104759 GAPDH 1 GO:0060441 epithelial tube branching involved in lung morphogenesis 1/320 29/18722 0.393673098831669 0.497600870104759 CTNNB1 1 GO:0090114 COPII-coated vesicle budding 1/320 29/18722 0.393673098831669 0.497600870104759 PDCD6 1 GO:0098868 bone growth 1/320 29/18722 0.393673098831669 0.497600870104759 ANXA6 1 GO:1901017 negative regulation of potassium ion transmembrane transporter activity 1/320 29/18722 0.393673098831669 0.497600870104759 CAV1 1 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 1/320 29/18722 0.393673098831669 0.497600870104759 CD74 1 GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus 1/320 29/18722 0.393673098831669 0.497600870104759 CD63 1 GO:1903318 negative regulation of protein maturation 1/320 29/18722 0.393673098831669 0.497600870104759 CARD16 1 GO:1903513 endoplasmic reticulum to cytosol transport 1/320 29/18722 0.393673098831669 0.497600870104759 UBE2J1 1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining 1/320 29/18722 0.393673098831669 0.497600870104759 DEK 1 GO:0006813 potassium ion transport 5/320 241/18722 0.394765318650425 0.49882883690017 FLNA/CAV1/FXYD3/CD63/ITGB1 5 GO:0010565 regulation of cellular ketone metabolic process 3/320 133/18722 0.397726603100418 0.5024170969156 CAV1/ANXA1/CD74 3 GO:0001570 vasculogenesis 2/320 80/18722 0.398217006585989 0.502882845725338 CAV1/CTNNB1 2 GO:0003299 muscle hypertrophy in response to stress 1/320 30/18722 0.404052631724938 0.505824460353656 EZH2 1 GO:0006099 tricarboxylic acid cycle 1/320 30/18722 0.404052631724938 0.505824460353656 IDH1 1 GO:0006221 pyrimidine nucleotide biosynthetic process 1/320 30/18722 0.404052631724938 0.505824460353656 UPP1 1 GO:0006921 cellular component disassembly involved in execution phase of apoptosis 1/320 30/18722 0.404052631724938 0.505824460353656 TOP2A 1 GO:0007176 regulation of epidermal growth factor-activated receptor activity 1/320 30/18722 0.404052631724938 0.505824460353656 NCF1 1 GO:0008209 androgen metabolic process 1/320 30/18722 0.404052631724938 0.505824460353656 CYP19A1 1 GO:0010453 regulation of cell fate commitment 1/320 30/18722 0.404052631724938 0.505824460353656 LMO4 1 GO:0014887 cardiac muscle adaptation 1/320 30/18722 0.404052631724938 0.505824460353656 EZH2 1 GO:0014898 cardiac muscle hypertrophy in response to stress 1/320 30/18722 0.404052631724938 0.505824460353656 EZH2 1 GO:0015865 purine nucleotide transport 1/320 30/18722 0.404052631724938 0.505824460353656 GJA1 1 GO:0031365 N-terminal protein amino acid modification 1/320 30/18722 0.404052631724938 0.505824460353656 SOX4 1 GO:0031571 mitotic G1 DNA damage checkpoint signaling 1/320 30/18722 0.404052631724938 0.505824460353656 SOX4 1 GO:0032480 negative regulation of type I interferon production 1/320 30/18722 0.404052631724938 0.505824460353656 REL 1 GO:0033137 negative regulation of peptidyl-serine phosphorylation 1/320 30/18722 0.404052631724938 0.505824460353656 CAV1 1 GO:0036296 response to increased oxygen levels 1/320 30/18722 0.404052631724938 0.505824460353656 CAV1 1 GO:0043032 positive regulation of macrophage activation 1/320 30/18722 0.404052631724938 0.505824460353656 CCL3 1 GO:0045070 positive regulation of viral genome replication 1/320 30/18722 0.404052631724938 0.505824460353656 TOP2A 1 GO:0045577 regulation of B cell differentiation 1/320 30/18722 0.404052631724938 0.505824460353656 ZFP36L2 1 GO:0060351 cartilage development involved in endochondral bone morphogenesis 1/320 30/18722 0.404052631724938 0.505824460353656 ANXA6 1 GO:0061384 heart trabecula morphogenesis 1/320 30/18722 0.404052631724938 0.505824460353656 TGFBR1 1 GO:0140058 neuron projection arborization 1/320 30/18722 0.404052631724938 0.505824460353656 LRP2 1 GO:1902751 positive regulation of cell cycle G2/M phase transition 1/320 30/18722 0.404052631724938 0.505824460353656 CDK1 1 GO:2000637 positive regulation of gene silencing by miRNA 1/320 30/18722 0.404052631724938 0.505824460353656 ZFP36 1 GO:0001523 retinoid metabolic process 2/320 81/18722 0.404218869333923 0.505824460353656 RDH13/LRP2 2 GO:0001942 hair follicle development 2/320 81/18722 0.404218869333923 0.505824460353656 CTNNB1/LGR5 2 GO:0010833 telomere maintenance via telomere lengthening 2/320 81/18722 0.404218869333923 0.505824460353656 PARP1/CTNNB1 2 GO:0021954 central nervous system neuron development 2/320 81/18722 0.404218869333923 0.505824460353656 NRP2/C12orf57 2 GO:0030641 regulation of cellular pH 2/320 81/18722 0.404218869333923 0.505824460353656 CLIC4/PPT1 2 GO:0048708 astrocyte differentiation 2/320 81/18722 0.404218869333923 0.505824460353656 VIM/S100A9 2 GO:0051149 positive regulation of muscle cell differentiation 2/320 81/18722 0.404218869333923 0.505824460353656 SOD2/MORF4L2 2 GO:0099111 microtubule-based transport 4/320 190/18722 0.408773655748139 0.511369284151169 ARMCX3/CDC42/DST/HSPB1 4 GO:0002312 B cell activation involved in immune response 2/320 82/18722 0.41019208873039 0.512368110832519 PTPRC/TFRC 2 GO:0046364 monosaccharide biosynthetic process 2/320 82/18722 0.41019208873039 0.512368110832519 TPI1/PGK1 2 GO:0046889 positive regulation of lipid biosynthetic process 2/320 82/18722 0.41019208873039 0.512368110832519 ANXA1/CD74 2 GO:0072527 pyrimidine-containing compound metabolic process 2/320 82/18722 0.41019208873039 0.512368110832519 UPP1/APOBEC3A 2 GO:2001252 positive regulation of chromosome organization 2/320 82/18722 0.41019208873039 0.512368110832519 PPP1R10/CTNNB1 2 GO:0072073 kidney epithelium development 3/320 136/18722 0.411492838932057 0.512946289580214 STAT1/MAGED1/CTNNB1 3 GO:0098876 vesicle-mediated transport to the plasma membrane 3/320 136/18722 0.411492838932057 0.512946289580214 RAB17/VAMP5/KRT18 3 GO:1903305 regulation of regulated secretory pathway 3/320 136/18722 0.411492838932057 0.512946289580214 ITGB2/HMOX1/STXBP2 3 GO:0002230 positive regulation of defense response to virus by host 1/320 31/18722 0.414255026217128 0.512946289580214 STAT1 1 GO:0002323 natural killer cell activation involved in immune response 1/320 31/18722 0.414255026217128 0.512946289580214 CORO1A 1 GO:0002717 positive regulation of natural killer cell mediated immunity 1/320 31/18722 0.414255026217128 0.512946289580214 HLA-E 1 GO:0006779 porphyrin-containing compound biosynthetic process 1/320 31/18722 0.414255026217128 0.512946289580214 TSPO 1 GO:0007190 activation of adenylate cyclase activity 1/320 31/18722 0.414255026217128 0.512946289580214 LGR5 1 GO:0018200 peptidyl-glutamic acid modification 1/320 31/18722 0.414255026217128 0.512946289580214 PARP1 1 GO:0030149 sphingolipid catabolic process 1/320 31/18722 0.414255026217128 0.512946289580214 PPT1 1 GO:0030201 heparan sulfate proteoglycan metabolic process 1/320 31/18722 0.414255026217128 0.512946289580214 CTNNB1 1 GO:0033014 tetrapyrrole biosynthetic process 1/320 31/18722 0.414255026217128 0.512946289580214 TSPO 1 GO:0033238 regulation of cellular amine metabolic process 1/320 31/18722 0.414255026217128 0.512946289580214 ITGB2 1 GO:0035115 embryonic forelimb morphogenesis 1/320 31/18722 0.414255026217128 0.512946289580214 CTNNB1 1 GO:0035510 DNA dealkylation 1/320 31/18722 0.414255026217128 0.512946289580214 APOBEC3A 1 GO:0044819 mitotic G1/S transition checkpoint signaling 1/320 31/18722 0.414255026217128 0.512946289580214 SOX4 1 GO:0045987 positive regulation of smooth muscle contraction 1/320 31/18722 0.414255026217128 0.512946289580214 RHOA 1 GO:0050482 arachidonic acid secretion 1/320 31/18722 0.414255026217128 0.512946289580214 ANXA1 1 GO:0051443 positive regulation of ubiquitin-protein transferase activity 1/320 31/18722 0.414255026217128 0.512946289580214 ARRDC3 1 GO:0051569 regulation of histone H3-K4 methylation 1/320 31/18722 0.414255026217128 0.512946289580214 CTNNB1 1 GO:0055022 negative regulation of cardiac muscle tissue growth 1/320 31/18722 0.414255026217128 0.512946289580214 GJA1 1 GO:0060045 positive regulation of cardiac muscle cell proliferation 1/320 31/18722 0.414255026217128 0.512946289580214 CDK1 1 GO:0060148 positive regulation of posttranscriptional gene silencing 1/320 31/18722 0.414255026217128 0.512946289580214 ZFP36 1 GO:0060795 cell fate commitment involved in formation of primary germ layer 1/320 31/18722 0.414255026217128 0.512946289580214 CTNNB1 1 GO:0061117 negative regulation of heart growth 1/320 31/18722 0.414255026217128 0.512946289580214 GJA1 1 GO:0071168 protein localization to chromatin 1/320 31/18722 0.414255026217128 0.512946289580214 EZH2 1 GO:0071480 cellular response to gamma radiation 1/320 31/18722 0.414255026217128 0.512946289580214 CYBA 1 GO:1903963 arachidonate transport 1/320 31/18722 0.414255026217128 0.512946289580214 ANXA1 1 GO:2000144 positive regulation of DNA-templated transcription, initiation 1/320 31/18722 0.414255026217128 0.512946289580214 JUN 1 GO:0008203 cholesterol metabolic process 3/320 137/18722 0.416060395636488 0.514812424235613 CYP11A1/DHCR24/NPC2 3 GO:0055123 digestive system development 3/320 137/18722 0.416060395636488 0.514812424235613 IGF2/WLS/CTNNB1 3 GO:0046785 microtubule polymerization 2/320 83/18722 0.416135889870994 0.514812424235613 STMN1/HSPA1A 2 GO:0000724 double-strand break repair via homologous recombination 3/320 138/18722 0.420616557911954 0.520199825588804 FUS/SAMHD1/PARP1 3 GO:1901988 negative regulation of cell cycle phase transition 5/320 249/18722 0.421772373412546 0.520682678739211 ZFP36L2/PPP1R10/CDK1/EZH2/SOX4 5 GO:0022404 molting cycle process 2/320 84/18722 0.422049532520259 0.520682678739211 CTNNB1/LGR5 2 GO:0022405 hair cycle process 2/320 84/18722 0.422049532520259 0.520682678739211 CTNNB1/LGR5 2 GO:0061157 mRNA destabilization 2/320 84/18722 0.422049532520259 0.520682678739211 ZFP36/ZFP36L2 2 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 2/320 84/18722 0.422049532520259 0.520682678739211 EZH2/SOX4 2 GO:0007435 salivary gland morphogenesis 1/320 32/18722 0.424283296058791 0.520682678739211 CDC42 1 GO:0008156 negative regulation of DNA replication 1/320 32/18722 0.424283296058791 0.520682678739211 GMNN 1 GO:0009954 proximal/distal pattern formation 1/320 32/18722 0.424283296058791 0.520682678739211 CTNNB1 1 GO:0010667 negative regulation of cardiac muscle cell apoptotic process 1/320 32/18722 0.424283296058791 0.520682678739211 PPP1R10 1 GO:0014044 Schwann cell development 1/320 32/18722 0.424283296058791 0.520682678739211 PLEC 1 GO:0019835 cytolysis 1/320 32/18722 0.424283296058791 0.520682678739211 LYZ 1 GO:0021799 cerebral cortex radially oriented cell migration 1/320 32/18722 0.424283296058791 0.520682678739211 CTNNB1 1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 1/320 32/18722 0.424283296058791 0.520682678739211 ZEB2 1 GO:0032196 transposition 1/320 32/18722 0.424283296058791 0.520682678739211 APOBEC3A 1 GO:0033687 osteoblast proliferation 1/320 32/18722 0.424283296058791 0.520682678739211 RHOA 1 GO:0045761 regulation of adenylate cyclase activity 1/320 32/18722 0.424283296058791 0.520682678739211 TIMP2 1 GO:0048841 regulation of axon extension involved in axon guidance 1/320 32/18722 0.424283296058791 0.520682678739211 SEMA6D 1 GO:0050685 positive regulation of mRNA processing 1/320 32/18722 0.424283296058791 0.520682678739211 TRA2B 1 GO:0050850 positive regulation of calcium-mediated signaling 1/320 32/18722 0.424283296058791 0.520682678739211 CCL3 1 GO:0051642 centrosome localization 1/320 32/18722 0.424283296058791 0.520682678739211 EZR 1 GO:0060323 head morphogenesis 1/320 32/18722 0.424283296058791 0.520682678739211 CRISPLD1 1 GO:0072525 pyridine-containing compound biosynthetic process 1/320 32/18722 0.424283296058791 0.520682678739211 NAMPT 1 GO:0090022 regulation of neutrophil chemotaxis 1/320 32/18722 0.424283296058791 0.520682678739211 CD74 1 GO:1900745 positive regulation of p38MAPK cascade 1/320 32/18722 0.424283296058791 0.520682678739211 NCF1 1 GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 1/320 32/18722 0.424283296058791 0.520682678739211 ZEB2 1 GO:1905476 negative regulation of protein localization to membrane 1/320 32/18722 0.424283296058791 0.520682678739211 GBP1 1 GO:0051783 regulation of nuclear division 3/320 139/18722 0.425160862091807 0.521604715606694 IGF2/CDC42/MKI67 3 GO:0030433 ubiquitin-dependent ERAD pathway 2/320 85/18722 0.427932310159479 0.524226595190918 CAV1/UBE2J1 2 GO:0032092 positive regulation of protein binding 2/320 85/18722 0.427932310159479 0.524226595190918 CAV1/B2M 2 GO:0071277 cellular response to calcium ion 2/320 85/18722 0.427932310159479 0.524226595190918 FUS/CLIC4 2 GO:0072384 organelle transport along microtubule 2/320 85/18722 0.427932310159479 0.524226595190918 ARMCX3/CDC42 2 GO:0098773 skin epidermis development 2/320 85/18722 0.427932310159479 0.524226595190918 CTNNB1/LGR5 2 GO:0006302 double-strand break repair 5/320 251/18722 0.428494856705804 0.524760150535975 FUS/SAMHD1/HMGB1/DEK/PARP1 5 GO:0000725 recombinational repair 3/320 140/18722 0.429692855331345 0.525604167622593 FUS/SAMHD1/PARP1 3 GO:0007292 female gamete generation 3/320 140/18722 0.429692855331345 0.525604167622593 CTNNB1/LGR5/TOP2A 3 GO:0015748 organophosphate ester transport 3/320 140/18722 0.429692855331345 0.525604167622593 DBI/NPC2/GJA1 3 GO:0046165 alcohol biosynthetic process 3/320 140/18722 0.429692855331345 0.525604167622593 PLEK/ISYNA1/DHCR24 3 GO:0009798 axis specification 2/320 86/18722 0.433783549056815 0.525906815845929 WLS/CTNNB1 2 GO:2001251 negative regulation of chromosome organization 2/320 86/18722 0.433783549056815 0.525906815845929 PARP1/TOP2A 2 GO:0006654 phosphatidic acid biosynthetic process 1/320 33/18722 0.434140403884429 0.525906815845929 ABHD8 1 GO:0009156 ribonucleoside monophosphate biosynthetic process 1/320 33/18722 0.434140403884429 0.525906815845929 UPP1 1 GO:0009648 photoperiodism 1/320 33/18722 0.434140403884429 0.525906815845929 BHLHE40 1 GO:0010165 response to X-ray 1/320 33/18722 0.434140403884429 0.525906815845929 ANXA1 1 GO:0019362 pyridine nucleotide metabolic process 1/320 33/18722 0.434140403884429 0.525906815845929 NAMPT 1 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 1/320 33/18722 0.434140403884429 0.525906815845929 PDCD6 1 GO:0031116 positive regulation of microtubule polymerization 1/320 33/18722 0.434140403884429 0.525906815845929 HSPA1A 1 GO:0034110 regulation of homotypic cell-cell adhesion 1/320 33/18722 0.434140403884429 0.525906815845929 PLAUR 1 GO:0046496 nicotinamide nucleotide metabolic process 1/320 33/18722 0.434140403884429 0.525906815845929 NAMPT 1 GO:0048048 embryonic eye morphogenesis 1/320 33/18722 0.434140403884429 0.525906815845929 FBN1 1 GO:0048730 epidermis morphogenesis 1/320 33/18722 0.434140403884429 0.525906815845929 CTNNB1 1 GO:0050901 leukocyte tethering or rolling 1/320 33/18722 0.434140403884429 0.525906815845929 ITGB1 1 GO:0050974 detection of mechanical stimulus involved in sensory perception 1/320 33/18722 0.434140403884429 0.525906815845929 CXCR4 1 GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 1/320 33/18722 0.434140403884429 0.525906815845929 HMGB1 1 GO:0061842 microtubule organizing center localization 1/320 33/18722 0.434140403884429 0.525906815845929 EZR 1 GO:0070570 regulation of neuron projection regeneration 1/320 33/18722 0.434140403884429 0.525906815845929 FLNA 1 GO:0071295 cellular response to vitamin 1/320 33/18722 0.434140403884429 0.525906815845929 ATP2B1 1 GO:0071539 protein localization to centrosome 1/320 33/18722 0.434140403884429 0.525906815845929 SNX10 1 GO:0071763 nuclear membrane organization 1/320 33/18722 0.434140403884429 0.525906815845929 NEK6 1 GO:0110110 positive regulation of animal organ morphogenesis 1/320 33/18722 0.434140403884429 0.525906815845929 CTNNB1 1 GO:0120033 negative regulation of plasma membrane bounded cell projection assembly 1/320 33/18722 0.434140403884429 0.525906815845929 CAPZB 1 GO:1900181 negative regulation of protein localization to nucleus 1/320 33/18722 0.434140403884429 0.525906815845929 MAGED1 1 GO:1901099 negative regulation of signal transduction in absence of ligand 1/320 33/18722 0.434140403884429 0.525906815845929 HSPA1A 1 GO:1901380 negative regulation of potassium ion transmembrane transport 1/320 33/18722 0.434140403884429 0.525906815845929 CAV1 1 GO:1901976 regulation of cell cycle checkpoint 1/320 33/18722 0.434140403884429 0.525906815845929 PPP1R10 1 GO:1902275 regulation of chromatin organization 1/320 33/18722 0.434140403884429 0.525906815845929 MKI67 1 GO:1902692 regulation of neuroblast proliferation 1/320 33/18722 0.434140403884429 0.525906815845929 CTNNB1 1 GO:1903715 regulation of aerobic respiration 1/320 33/18722 0.434140403884429 0.525906815845929 RHOA 1 GO:1904031 positive regulation of cyclin-dependent protein kinase activity 1/320 33/18722 0.434140403884429 0.525906815845929 CKS2 1 GO:2000036 regulation of stem cell population maintenance 1/320 33/18722 0.434140403884429 0.525906815845929 LBH 1 GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 1/320 33/18722 0.434140403884429 0.525906815845929 HSPA1A 1 GO:0072006 nephron development 3/320 142/18722 0.438718151165878 0.531296424565477 STAT1/MAGED1/CTNNB1 3 GO:0016101 diterpenoid metabolic process 2/320 87/18722 0.43960260735918 0.531744137473106 RDH13/LRP2 2 GO:0019646 aerobic electron transport chain 2/320 87/18722 0.43960260735918 0.531744137473106 NDUFB1/NDUFB7 2 GO:0019915 lipid storage 2/320 87/18722 0.43960260735918 0.531744137473106 CAV1/PLIN2 2 GO:0061014 positive regulation of mRNA catabolic process 2/320 87/18722 0.43960260735918 0.531744137473106 ZFP36/ZFP36L2 2 GO:0007611 learning or memory 5/320 255/18722 0.441892347261873 0.533421323706017 ITGB1/JUN/B2M/PPT1/CEBPB 5 GO:0019932 second-messenger-mediated signaling 6/320 312/18722 0.443179385421169 0.533421323706017 PTPRC/PLEK/CXCR4/CCL3/GBP1/GSTO1 6 GO:0006865 amino acid transport 3/320 143/18722 0.443210601341152 0.533421323706017 ITGB1/SLC43A2/GJA1 3 GO:0000038 very long-chain fatty acid metabolic process 1/320 34/18722 0.443829262076788 0.533421323706017 SLC27A2 1 GO:0001662 behavioral fear response 1/320 34/18722 0.443829262076788 0.533421323706017 GJA1 1 GO:0002183 cytoplasmic translational initiation 1/320 34/18722 0.443829262076788 0.533421323706017 EIF4H 1 GO:0007095 mitotic G2 DNA damage checkpoint signaling 1/320 34/18722 0.443829262076788 0.533421323706017 CDK1 1 GO:0007431 salivary gland development 1/320 34/18722 0.443829262076788 0.533421323706017 CDC42 1 GO:0009649 entrainment of circadian clock 1/320 34/18722 0.443829262076788 0.533421323706017 BHLHE40 1 GO:0010614 negative regulation of cardiac muscle hypertrophy 1/320 34/18722 0.443829262076788 0.533421323706017 TNFRSF1B 1 GO:0016242 negative regulation of macroautophagy 1/320 34/18722 0.443829262076788 0.533421323706017 HMOX1 1 GO:0019320 hexose catabolic process 1/320 34/18722 0.443829262076788 0.533421323706017 ENO1 1 GO:0030851 granulocyte differentiation 1/320 34/18722 0.443829262076788 0.533421323706017 EVI2B 1 GO:0031128 developmental induction 1/320 34/18722 0.443829262076788 0.533421323706017 CTNNB1 1 GO:0032212 positive regulation of telomere maintenance via telomerase 1/320 34/18722 0.443829262076788 0.533421323706017 CTNNB1 1 GO:0034383 low-density lipoprotein particle clearance 1/320 34/18722 0.443829262076788 0.533421323706017 HMOX1 1 GO:0035137 hindlimb morphogenesis 1/320 34/18722 0.443829262076788 0.533421323706017 CTNNB1 1 GO:0035909 aorta morphogenesis 1/320 34/18722 0.443829262076788 0.533421323706017 SOX4 1 GO:0051973 positive regulation of telomerase activity 1/320 34/18722 0.443829262076788 0.533421323706017 CTNNB1 1 GO:0070050 neuron cellular homeostasis 1/320 34/18722 0.443829262076788 0.533421323706017 ATP2B1 1 GO:0070232 regulation of T cell apoptotic process 1/320 34/18722 0.443829262076788 0.533421323706017 TSC22D3 1 GO:1990000 amyloid fibril formation 1/320 34/18722 0.443829262076788 0.533421323706017 B2M 1 GO:0031110 regulation of microtubule polymerization or depolymerization 2/320 88/18722 0.445388874205401 0.534984543086255 STMN1/HSPA1A 2 GO:1901657 glycosyl compound metabolic process 2/320 88/18722 0.445388874205401 0.534984543086255 UPP1/APOBEC3A 2 GO:0007612 learning 3/320 144/18722 0.447689035541216 0.537434949115719 ITGB1/JUN/PPT1 3 GO:0014065 phosphatidylinositol 3-kinase signaling 3/320 144/18722 0.447689035541216 0.537434949115719 NCF1/FN1/FLT1 3 GO:0006473 protein acetylation 4/320 201/18722 0.450705079007979 0.540777567928309 MBD3/ISL1/MORF4L2/SOX4 4 GO:0000460 maturation of 5.8S rRNA 1/320 35/18722 0.453352733616569 0.540777567928309 RPS21 1 GO:0000731 DNA synthesis involved in DNA repair 1/320 35/18722 0.453352733616569 0.540777567928309 RFC3 1 GO:0001569 branching involved in blood vessel morphogenesis 1/320 35/18722 0.453352733616569 0.540777567928309 CTNNB1 1 GO:0002209 behavioral defense response 1/320 35/18722 0.453352733616569 0.540777567928309 GJA1 1 GO:0006298 mismatch repair 1/320 35/18722 0.453352733616569 0.540777567928309 HMGB1 1 GO:0006739 NADP metabolic process 1/320 35/18722 0.453352733616569 0.540777567928309 IDH1 1 GO:0007020 microtubule nucleation 1/320 35/18722 0.453352733616569 0.540777567928309 HSPA1A 1 GO:0008608 attachment of spindle microtubules to kinetochore 1/320 35/18722 0.453352733616569 0.540777567928309 CDC42 1 GO:0010664 negative regulation of striated muscle cell apoptotic process 1/320 35/18722 0.453352733616569 0.540777567928309 PPP1R10 1 GO:0010837 regulation of keratinocyte proliferation 1/320 35/18722 0.453352733616569 0.540777567928309 ZFP36 1 GO:0021955 central nervous system neuron axonogenesis 1/320 35/18722 0.453352733616569 0.540777567928309 C12orf57 1 GO:0032205 negative regulation of telomere maintenance 1/320 35/18722 0.453352733616569 0.540777567928309 PARP1 1 GO:0032350 regulation of hormone metabolic process 1/320 35/18722 0.453352733616569 0.540777567928309 STC2 1 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 1/320 35/18722 0.453352733616569 0.540777567928309 PBK 1 GO:0042462 eye photoreceptor cell development 1/320 35/18722 0.453352733616569 0.540777567928309 RDH13 1 GO:0043243 positive regulation of protein-containing complex disassembly 1/320 35/18722 0.453352733616569 0.540777567928309 PLEK 1 GO:0045454 cell redox homeostasis 1/320 35/18722 0.453352733616569 0.540777567928309 GPX1 1 GO:0048821 erythrocyte development 1/320 35/18722 0.453352733616569 0.540777567928309 KLF2 1 GO:0072528 pyrimidine-containing compound biosynthetic process 1/320 35/18722 0.453352733616569 0.540777567928309 UPP1 1 GO:0098810 neurotransmitter reuptake 1/320 35/18722 0.453352733616569 0.540777567928309 ITGB1 1 GO:1905508 protein localization to microtubule organizing center 1/320 35/18722 0.453352733616569 0.540777567928309 SNX10 1 GO:0017157 regulation of exocytosis 4/320 202/18722 0.454473545055049 0.541801698836545 ITGB2/ANXA1/HMOX1/STXBP2 4 GO:1903046 meiotic cell cycle process 4/320 202/18722 0.454473545055049 0.541801698836545 MYH9/ACTR3/TOP2A/CKS2 4 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 3/320 146/18722 0.456602265607997 0.543549835052753 ARRDC3/PDE4B/LGR5 3 GO:0048813 dendrite morphogenesis 3/320 146/18722 0.456602265607997 0.543549835052753 CDC42/ITGB1/ID1 3 GO:0002028 regulation of sodium ion transport 2/320 90/18722 0.45686073986888 0.543549835052753 FXYD5/FXYD3 2 GO:0035304 regulation of protein dephosphorylation 2/320 90/18722 0.45686073986888 0.543549835052753 PTPRC/SLC39A10 2 GO:0042475 odontogenesis of dentin-containing tooth 2/320 90/18722 0.45686073986888 0.543549835052753 HTRA1/CTNNB1 2 GO:0048477 oogenesis 2/320 90/18722 0.45686073986888 0.543549835052753 CTNNB1/LGR5 2 GO:0099175 regulation of postsynapse organization 2/320 90/18722 0.45686073986888 0.543549835052753 SRGN/NRP2 2 GO:0060541 respiratory system development 4/320 203/18722 0.458233552841285 0.5450262062004 KLF2/CDC42/HMGB1/CTNNB1 4 GO:0090150 establishment of protein localization to membrane 5/320 260/18722 0.458532987320426 0.545225411110216 ITGB2/NCF1/VAMP5/KRT18/TCAF1 5 GO:0060041 retina development in camera-type eye 3/320 147/18722 0.461036291758322 0.546891513505858 RDH13/ATP2B1/CLIC4 3 GO:0001657 ureteric bud development 2/320 91/18722 0.462545264231144 0.546891513505858 MAGED1/CTNNB1 2 GO:0002065 columnar/cuboidal epithelial cell differentiation 2/320 91/18722 0.462545264231144 0.546891513505858 SOX4/CEBPB 2 GO:0006885 regulation of pH 2/320 91/18722 0.462545264231144 0.546891513505858 CLIC4/PPT1 2 GO:0051952 regulation of amine transport 2/320 91/18722 0.462545264231144 0.546891513505858 ITGB1/SLC43A2 2 GO:0051983 regulation of chromosome segregation 2/320 91/18722 0.462545264231144 0.546891513505858 NEK6/MKI67 2 GO:0002691 regulation of cellular extravasation 1/320 36/18722 0.462713632917832 0.546891513505858 CD99 1 GO:0003352 regulation of cilium movement 1/320 36/18722 0.462713632917832 0.546891513505858 CCSAP 1 GO:0006699 bile acid biosynthetic process 1/320 36/18722 0.462713632917832 0.546891513505858 SLC27A2 1 GO:0009225 nucleotide-sugar metabolic process 1/320 36/18722 0.462713632917832 0.546891513505858 UGP2 1 GO:0010762 regulation of fibroblast migration 1/320 36/18722 0.462713632917832 0.546891513505858 ITGB1 1 GO:0014741 negative regulation of muscle hypertrophy 1/320 36/18722 0.462713632917832 0.546891513505858 TNFRSF1B 1 GO:0017004 cytochrome complex assembly 1/320 36/18722 0.462713632917832 0.546891513505858 CYBA 1 GO:0038179 neurotrophin signaling pathway 1/320 36/18722 0.462713632917832 0.546891513505858 CORO1A 1 GO:0044060 regulation of endocrine process 1/320 36/18722 0.462713632917832 0.546891513505858 GJA1 1 GO:0046466 membrane lipid catabolic process 1/320 36/18722 0.462713632917832 0.546891513505858 PPT1 1 GO:0051354 negative regulation of oxidoreductase activity 1/320 36/18722 0.462713632917832 0.546891513505858 CAV1 1 GO:0060251 regulation of glial cell proliferation 1/320 36/18722 0.462713632917832 0.546891513505858 TSPO 1 GO:0070306 lens fiber cell differentiation 1/320 36/18722 0.462713632917832 0.546891513505858 VIM 1 GO:0070897 transcription preinitiation complex assembly 1/320 36/18722 0.462713632917832 0.546891513505858 HMGB1 1 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 1/320 36/18722 0.462713632917832 0.546891513505858 CD74 1 GO:0043484 regulation of RNA splicing 3/320 148/18722 0.465454762290473 0.549816774666734 FUS/TRA2B/HSPA1A 3 GO:0050905 neuromuscular process 3/320 148/18722 0.465454762290473 0.549816774666734 C12orf57/UBA5/GSTO1 3 GO:0031058 positive regulation of histone modification 2/320 92/18722 0.468194846595542 0.55194896038025 ISL1/CTNNB1 2 GO:0032465 regulation of cytokinesis 2/320 92/18722 0.468194846595542 0.55194896038025 CDC42/RHOA 2 GO:0034502 protein localization to chromosome 2/320 92/18722 0.468194846595542 0.55194896038025 CDK1/EZH2 2 GO:0070509 calcium ion import 2/320 92/18722 0.468194846595542 0.55194896038025 CCL3/CTNNB1 2 GO:0072163 mesonephric epithelium development 2/320 92/18722 0.468194846595542 0.55194896038025 MAGED1/CTNNB1 2 GO:0072164 mesonephric tubule development 2/320 92/18722 0.468194846595542 0.55194896038025 MAGED1/CTNNB1 2 GO:1903351 cellular response to dopamine 2/320 92/18722 0.468194846595542 0.55194896038025 FLNA/ID1 2 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/320 37/18722 0.471914726649304 0.553806205769646 RPS21 1 GO:0003176 aortic valve development 1/320 37/18722 0.471914726649304 0.553806205769646 TNFRSF1B 1 GO:0006862 nucleotide transport 1/320 37/18722 0.471914726649304 0.553806205769646 GJA1 1 GO:0007340 acrosome reaction 1/320 37/18722 0.471914726649304 0.553806205769646 SPESP1 1 GO:0031112 positive regulation of microtubule polymerization or depolymerization 1/320 37/18722 0.471914726649304 0.553806205769646 HSPA1A 1 GO:0031646 positive regulation of nervous system process 1/320 37/18722 0.471914726649304 0.553806205769646 TNFRSF1B 1 GO:0032885 regulation of polysaccharide biosynthetic process 1/320 37/18722 0.471914726649304 0.553806205769646 IGF2 1 GO:0033363 secretory granule organization 1/320 37/18722 0.471914726649304 0.553806205769646 SRGN 1 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 1/320 37/18722 0.471914726649304 0.553806205769646 CTNNB1 1 GO:0045616 regulation of keratinocyte differentiation 1/320 37/18722 0.471914726649304 0.553806205769646 ZFP36 1 GO:0046473 phosphatidic acid metabolic process 1/320 37/18722 0.471914726649304 0.553806205769646 ABHD8 1 GO:0048009 insulin-like growth factor receptor signaling pathway 1/320 37/18722 0.471914726649304 0.553806205769646 IGFBP3 1 GO:0051954 positive regulation of amine transport 1/320 37/18722 0.471914726649304 0.553806205769646 ITGB1 1 GO:0071542 dopaminergic neuron differentiation 1/320 37/18722 0.471914726649304 0.553806205769646 CTNNB1 1 GO:0097484 dendrite extension 1/320 37/18722 0.471914726649304 0.553806205769646 CXCR4 1 GO:1904358 positive regulation of telomere maintenance via telomere lengthening 1/320 37/18722 0.471914726649304 0.553806205769646 CTNNB1 1 GO:0007589 body fluid secretion 2/320 93/18722 0.473809018472185 0.55508331849364 CAV1/CYBA 2 GO:0032088 negative regulation of NF-kappaB transcription factor activity 2/320 93/18722 0.473809018472185 0.55508331849364 TMSB4X/ANXA4 2 GO:0033108 mitochondrial respiratory chain complex assembly 2/320 93/18722 0.473809018472185 0.55508331849364 NDUFB1/NDUFB7 2 GO:0045132 meiotic chromosome segregation 2/320 93/18722 0.473809018472185 0.55508331849364 ACTR3/TOP2A 2 GO:1902807 negative regulation of cell cycle G1/S phase transition 2/320 93/18722 0.473809018472185 0.55508331849364 EZH2/SOX4 2 GO:1903350 response to dopamine 2/320 93/18722 0.473809018472185 0.55508331849364 FLNA/ID1 2 GO:0006836 neurotransmitter transport 4/320 208/18722 0.476897671867343 0.558543418411525 SLC6A8/ITGB1/STXBP2/PPT1 4 GO:0048754 branching morphogenesis of an epithelial tube 3/320 151/18722 0.478613290657663 0.559808870739979 CLIC4/MAGED1/CTNNB1 3 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 2/320 94/18722 0.479387337464482 0.559808870739979 ACTB/CKS2 2 GO:0048704 embryonic skeletal system morphogenesis 2/320 94/18722 0.479387337464482 0.559808870739979 TGFBR1/CTNNB1 2 GO:0000578 embryonic axis specification 1/320 38/18722 0.48095873454185 0.559808870739979 CTNNB1 1 GO:0002385 mucosal immune response 1/320 38/18722 0.48095873454185 0.559808870739979 RAB17 1 GO:0008210 estrogen metabolic process 1/320 38/18722 0.48095873454185 0.559808870739979 CYP19A1 1 GO:0010613 positive regulation of cardiac muscle hypertrophy 1/320 38/18722 0.48095873454185 0.559808870739979 PARP1 1 GO:0010742 macrophage derived foam cell differentiation 1/320 38/18722 0.48095873454185 0.559808870739979 STAT1 1 GO:0032373 positive regulation of sterol transport 1/320 38/18722 0.48095873454185 0.559808870739979 CAV1 1 GO:0032376 positive regulation of cholesterol transport 1/320 38/18722 0.48095873454185 0.559808870739979 CAV1 1 GO:0032941 secretion by tissue 1/320 38/18722 0.48095873454185 0.559808870739979 CYBA 1 GO:0035136 forelimb morphogenesis 1/320 38/18722 0.48095873454185 0.559808870739979 CTNNB1 1 GO:0035337 fatty-acyl-CoA metabolic process 1/320 38/18722 0.48095873454185 0.559808870739979 PPT1 1 GO:0042596 fear response 1/320 38/18722 0.48095873454185 0.559808870739979 GJA1 1 GO:0046329 negative regulation of JNK cascade 1/320 38/18722 0.48095873454185 0.559808870739979 PDCD4 1 GO:0048246 macrophage chemotaxis 1/320 38/18722 0.48095873454185 0.559808870739979 CCL3 1 GO:0051930 regulation of sensory perception of pain 1/320 38/18722 0.48095873454185 0.559808870739979 CCL3 1 GO:0072524 pyridine-containing compound metabolic process 1/320 38/18722 0.48095873454185 0.559808870739979 NAMPT 1 GO:0090077 foam cell differentiation 1/320 38/18722 0.48095873454185 0.559808870739979 STAT1 1 GO:0099622 cardiac muscle cell membrane repolarization 1/320 38/18722 0.48095873454185 0.559808870739979 FLNA 1 GO:1903725 regulation of phospholipid metabolic process 1/320 38/18722 0.48095873454185 0.559808870739979 IDH1 1 GO:2000279 negative regulation of DNA biosynthetic process 1/320 38/18722 0.48095873454185 0.559808870739979 GJA1 1 GO:0006644 phospholipid metabolic process 7/320 383/18722 0.482359208290181 0.561280836005358 PLEK/DBI/ABHD8/ISYNA1/GPX4/PLPP3/IDH1 7 GO:0016573 histone acetylation 3/320 152/18722 0.482966037808535 0.561670607437339 MBD3/ISL1/MORF4L2 3 GO:0031056 regulation of histone modification 3/320 152/18722 0.482966037808535 0.561670607437339 IGF2/ISL1/CTNNB1 3 GO:0030516 regulation of axon extension 2/320 95/18722 0.484929386519091 0.563636631532176 FN1/SEMA6D 2 GO:0045666 positive regulation of neuron differentiation 2/320 95/18722 0.484929386519091 0.563636631532176 TIMP2/RHOA 2 GO:0014742 positive regulation of muscle hypertrophy 1/320 39/18722 0.489848330182323 0.567916189762447 PARP1 1 GO:0016572 histone phosphorylation 1/320 39/18722 0.489848330182323 0.567916189762447 CDK1 1 GO:0031507 heterochromatin assembly 1/320 39/18722 0.489848330182323 0.567916189762447 MBD3 1 GO:0042417 dopamine metabolic process 1/320 39/18722 0.489848330182323 0.567916189762447 ITGB2 1 GO:0043267 negative regulation of potassium ion transport 1/320 39/18722 0.489848330182323 0.567916189762447 CAV1 1 GO:0046621 negative regulation of organ growth 1/320 39/18722 0.489848330182323 0.567916189762447 GJA1 1 GO:0051931 regulation of sensory perception 1/320 39/18722 0.489848330182323 0.567916189762447 CCL3 1 GO:1901021 positive regulation of calcium ion transmembrane transporter activity 1/320 39/18722 0.489848330182323 0.567916189762447 GSTO1 1 GO:1902742 apoptotic process involved in development 1/320 39/18722 0.489848330182323 0.567916189762447 TNFRSF1B 1 GO:0001823 mesonephros development 2/320 96/18722 0.490434773193765 0.567958655503542 MAGED1/CTNNB1 2 GO:0015914 phospholipid transport 2/320 96/18722 0.490434773193765 0.567958655503542 DBI/NPC2 2 GO:0042632 cholesterol homeostasis 2/320 96/18722 0.490434773193765 0.567958655503542 CAV1/NPC2 2 GO:0051304 chromosome separation 2/320 96/18722 0.490434773193765 0.567958655503542 NEK6/TOP2A 2 GO:0006457 protein folding 4/320 212/18722 0.49165112018468 0.569207741272933 CD74/B2M/HSPA1A/HSPB1 4 GO:0006721 terpenoid metabolic process 2/320 97/18722 0.495903128942681 0.573346208276865 RDH13/LRP2 2 GO:0010596 negative regulation of endothelial cell migration 2/320 97/18722 0.495903128942681 0.573346208276865 HMGB1/RHOA 2 GO:0043255 regulation of carbohydrate biosynthetic process 2/320 97/18722 0.495903128942681 0.573346208276865 PLEK/IGF2 2 GO:0055092 sterol homeostasis 2/320 97/18722 0.495903128942681 0.573346208276865 CAV1/NPC2 2 GO:0006665 sphingolipid metabolic process 3/320 155/18722 0.495919493799979 0.573346208276865 PSAP/PLPP3/PPT1 3 GO:0009187 cyclic nucleotide metabolic process 1/320 40/18722 0.498586141794037 0.57530241214548 PDE4B 1 GO:0010863 positive regulation of phospholipase C activity 1/320 40/18722 0.498586141794037 0.57530241214548 FLT1 1 GO:0031111 negative regulation of microtubule polymerization or depolymerization 1/320 40/18722 0.498586141794037 0.57530241214548 STMN1 1 GO:0031297 replication fork processing 1/320 40/18722 0.498586141794037 0.57530241214548 SAMHD1 1 GO:0032094 response to food 1/320 40/18722 0.498586141794037 0.57530241214548 PLEC 1 GO:0032892 positive regulation of organic acid transport 1/320 40/18722 0.498586141794037 0.57530241214548 ITGB1 1 GO:0046365 monosaccharide catabolic process 1/320 40/18722 0.498586141794037 0.57530241214548 ENO1 1 GO:0044242 cellular lipid catabolic process 4/320 214/18722 0.498963459112068 0.57541641447141 CROT/SLC27A2/PPT1/IDH1 4 GO:0072330 monocarboxylic acid biosynthetic process 4/320 214/18722 0.498963459112068 0.57541641447141 ANXA1/CD74/SLC27A2/GPX4 4 GO:0009267 cellular response to starvation 3/320 156/18722 0.5002013750181 0.576683058475108 UPP1/PMAIP1/JUN 3 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 5/320 273/18722 0.501080445964028 0.577505585722563 FXYD5/ITGB2/MYADM/ITGB1/EMB 5 GO:0003333 amino acid transmembrane transport 2/320 98/18722 0.501334108418885 0.577505585722563 ITGB1/SLC43A2 2 GO:1904029 regulation of cyclin-dependent protein kinase activity 2/320 98/18722 0.501334108418885 0.577505585722563 ACTB/CKS2 2 GO:0015837 amine transport 2/320 99/18722 0.506727388793481 0.582609418797007 ITGB1/SLC43A2 2 GO:0021549 cerebellum development 2/320 99/18722 0.506727388793481 0.582609418797007 AIF1/EZH2 2 GO:0002251 organ or tissue specific immune response 1/320 41/18722 0.507174753004074 0.582609418797007 RAB17 1 GO:0031062 positive regulation of histone methylation 1/320 41/18722 0.507174753004074 0.582609418797007 CTNNB1 1 GO:0050691 regulation of defense response to virus by host 1/320 41/18722 0.507174753004074 0.582609418797007 STAT1 1 GO:0050892 intestinal absorption 1/320 41/18722 0.507174753004074 0.582609418797007 EZR 1 GO:0055023 positive regulation of cardiac muscle tissue growth 1/320 41/18722 0.507174753004074 0.582609418797007 CDK1 1 GO:0060612 adipose tissue development 1/320 41/18722 0.507174753004074 0.582609418797007 ARRDC3 1 GO:1905314 semi-lunar valve development 1/320 41/18722 0.507174753004074 0.582609418797007 TNFRSF1B 1 GO:1905521 regulation of macrophage migration 1/320 41/18722 0.507174753004074 0.582609418797007 CCL3 1 GO:0018393 internal peptidyl-lysine acetylation 3/320 158/18722 0.508709510603107 0.584210032743757 MBD3/ISL1/MORF4L2 3 GO:0006626 protein targeting to mitochondrion 2/320 100/18722 0.512082669091181 0.587593887443699 TSPO/BNIP3L 2 GO:0006641 triglyceride metabolic process 2/320 100/18722 0.512082669091181 0.587593887443699 CAV1/GPX1 2 GO:0009062 fatty acid catabolic process 2/320 100/18722 0.512082669091181 0.587593887443699 CROT/SLC27A2 2 GO:0032200 telomere organization 3/320 159/18722 0.512935222576266 0.588408756159115 PARP1/PPP1R10/CTNNB1 3 GO:0007212 dopamine receptor signaling pathway 1/320 42/18722 0.515616703597656 0.589031854925495 FLNA 1 GO:0009124 nucleoside monophosphate biosynthetic process 1/320 42/18722 0.515616703597656 0.589031854925495 UPP1 1 GO:0009154 purine ribonucleotide catabolic process 1/320 42/18722 0.515616703597656 0.589031854925495 PDE4B 1 GO:0010677 negative regulation of cellular carbohydrate metabolic process 1/320 42/18722 0.515616703597656 0.589031854925495 PLEK 1 GO:0016601 Rac protein signal transduction 1/320 42/18722 0.515616703597656 0.589031854925495 AIF1 1 GO:0032965 regulation of collagen biosynthetic process 1/320 42/18722 0.515616703597656 0.589031854925495 VIM 1 GO:0045773 positive regulation of axon extension 1/320 42/18722 0.515616703597656 0.589031854925495 FN1 1 GO:0048489 synaptic vesicle transport 1/320 42/18722 0.515616703597656 0.589031854925495 CTNNB1 1 GO:0071312 cellular response to alkaloid 1/320 42/18722 0.515616703597656 0.589031854925495 AIF1 1 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis 1/320 42/18722 0.515616703597656 0.589031854925495 RHOA 1 GO:0090317 negative regulation of intracellular protein transport 1/320 42/18722 0.515616703597656 0.589031854925495 UBE2J1 1 GO:1900274 regulation of phospholipase C activity 1/320 42/18722 0.515616703597656 0.589031854925495 FLT1 1 GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II 1/320 42/18722 0.515616703597656 0.589031854925495 JUN 1 GO:1904037 positive regulation of epithelial cell apoptotic process 1/320 42/18722 0.515616703597656 0.589031854925495 PDCD4 1 GO:2001222 regulation of neuron migration 1/320 42/18722 0.515616703597656 0.589031854925495 FLNA 1 GO:0071805 potassium ion transmembrane transport 4/320 219/18722 0.517042792613984 0.590415751048627 FLNA/CAV1/CD63/ITGB1 4 GO:0006475 internal protein amino acid acetylation 3/320 160/18722 0.517141683605449 0.590415751048627 MBD3/ISL1/MORF4L2 3 GO:0060271 cilium assembly 6/320 337/18722 0.517280090874867 0.590415751048627 FLNA/RAB17/DYNLL1/GALNT11/SNX10/ACTR3 6 GO:0006476 protein deacetylation 2/320 101/18722 0.517399669541887 0.590415751048627 FLNA/MORF4L2 2 GO:0018209 peptidyl-serine modification 6/320 338/18722 0.520171603154035 0.593414981842207 CAV1/NEK6/TGFBR1/PARP1/CDK1/TFRC 6 GO:0051650 establishment of vesicle localization 3/320 161/18722 0.52132864411562 0.594076474685366 RAB17/CTNNB1/PDCD6 3 GO:0034308 primary alcohol metabolic process 2/320 102/18722 0.522678130947921 0.594076474685366 CYP11A1/RDH13 2 GO:0062014 negative regulation of small molecule metabolic process 2/320 102/18722 0.522678130947921 0.594076474685366 PLEK/PARP1 2 GO:0006790 sulfur compound metabolic process 6/320 339/18722 0.523056402752423 0.594076474685366 CLIC3/GPX1/GSTO1/GPX4/PPT1/IDH1 6 GO:0001504 neurotransmitter uptake 1/320 43/18722 0.523914490259795 0.594076474685366 ITGB1 1 GO:0006284 base-excision repair 1/320 43/18722 0.523914490259795 0.594076474685366 HMGB1 1 GO:0010171 body morphogenesis 1/320 43/18722 0.523914490259795 0.594076474685366 CRISPLD1 1 GO:0016266 O-glycan processing 1/320 43/18722 0.523914490259795 0.594076474685366 GALNT11 1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 1/320 43/18722 0.523914490259795 0.594076474685366 FXYD5 1 GO:0021983 pituitary gland development 1/320 43/18722 0.523914490259795 0.594076474685366 ISL1 1 GO:0030517 negative regulation of axon extension 1/320 43/18722 0.523914490259795 0.594076474685366 SEMA6D 1 GO:0032365 intracellular lipid transport 1/320 43/18722 0.523914490259795 0.594076474685366 NPC2 1 GO:0034142 toll-like receptor 4 signaling pathway 1/320 43/18722 0.523914490259795 0.594076474685366 HMGB1 1 GO:0042181 ketone biosynthetic process 1/320 43/18722 0.523914490259795 0.594076474685366 TPI1 1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/320 43/18722 0.523914490259795 0.594076474685366 CD74 1 GO:0045776 negative regulation of blood pressure 1/320 43/18722 0.523914490259795 0.594076474685366 SOD2 1 GO:0045840 positive regulation of mitotic nuclear division 1/320 43/18722 0.523914490259795 0.594076474685366 IGF2 1 GO:0046717 acid secretion 1/320 43/18722 0.523914490259795 0.594076474685366 SNX10 1 GO:0060443 mammary gland morphogenesis 1/320 43/18722 0.523914490259795 0.594076474685366 CAV1 1 GO:0140353 lipid export from cell 1/320 43/18722 0.523914490259795 0.594076474685366 CYP19A1 1 GO:1901381 positive regulation of potassium ion transmembrane transport 1/320 43/18722 0.523914490259795 0.594076474685366 FLNA 1 GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 1/320 43/18722 0.523914490259795 0.594076474685366 HSPA1A 1 GO:0098813 nuclear chromosome segregation 5/320 281/18722 0.526621173556277 0.596981807718666 NEK6/CDC42/ACTR3/CTNNB1/TOP2A 5 GO:0019233 sensory perception of pain 2/320 103/18722 0.527917814066589 0.597959541590775 CXCR4/CCL3 2 GO:0019395 fatty acid oxidation 2/320 103/18722 0.527917814066589 0.597959541590775 CROT/SLC27A2 2 GO:0030004 cellular monovalent inorganic cation homeostasis 2/320 103/18722 0.527917814066589 0.597959541590775 CLIC4/PPT1 2 GO:0006633 fatty acid biosynthetic process 3/320 163/18722 0.529643107351551 0.599585019062085 ANXA1/CD74/GPX4 3 GO:0010976 positive regulation of neuron projection development 3/320 163/18722 0.529643107351551 0.599585019062085 FLNA/S100A9/EZH2 3 GO:0002792 negative regulation of peptide secretion 1/320 44/18722 0.532070567304437 0.600851485133078 CD74 1 GO:0008542 visual learning 1/320 44/18722 0.532070567304437 0.600851485133078 ITGB1 1 GO:0030521 androgen receptor signaling pathway 1/320 44/18722 0.532070567304437 0.600851485133078 RHOA 1 GO:0032007 negative regulation of TOR signaling 1/320 44/18722 0.532070567304437 0.600851485133078 PDCD6 1 GO:0045124 regulation of bone resorption 1/320 44/18722 0.532070567304437 0.600851485133078 TFRC 1 GO:0050999 regulation of nitric-oxide synthase activity 1/320 44/18722 0.532070567304437 0.600851485133078 CAV1 1 GO:0060324 face development 1/320 44/18722 0.532070567304437 0.600851485133078 CRISPLD1 1 GO:1903214 regulation of protein targeting to mitochondrion 1/320 44/18722 0.532070567304437 0.600851485133078 BNIP3L 1 GO:1903573 negative regulation of response to endoplasmic reticulum stress 1/320 44/18722 0.532070567304437 0.600851485133078 HSPA1A 1 GO:0022600 digestive system process 2/320 104/18722 0.533118499007725 0.601870392868831 EZR/SNX10 2 GO:0002920 regulation of humoral immune response 1/320 45/18722 0.540087347391308 0.608242278392173 PTPRC 1 GO:0006903 vesicle targeting 1/320 45/18722 0.540087347391308 0.608242278392173 PDCD6 1 GO:0032309 icosanoid secretion 1/320 45/18722 0.540087347391308 0.608242278392173 ANXA1 1 GO:0035384 thioester biosynthetic process 1/320 45/18722 0.540087347391308 0.608242278392173 PPT1 1 GO:0046189 phenol-containing compound biosynthetic process 1/320 45/18722 0.540087347391308 0.608242278392173 ZEB2 1 GO:0048546 digestive tract morphogenesis 1/320 45/18722 0.540087347391308 0.608242278392173 CTNNB1 1 GO:0048599 oocyte development 1/320 45/18722 0.540087347391308 0.608242278392173 CTNNB1 1 GO:0060421 positive regulation of heart growth 1/320 45/18722 0.540087347391308 0.608242278392173 CDK1 1 GO:0071616 acyl-CoA biosynthetic process 1/320 45/18722 0.540087347391308 0.608242278392173 PPT1 1 GO:0006906 vesicle fusion 2/320 106/18722 0.543402088046909 0.611641903516706 CORO1A/ANXA1 2 GO:0046822 regulation of nucleocytoplasmic transport 2/320 106/18722 0.543402088046909 0.611641903516706 FLNA/CDK1 2 GO:0046777 protein autophosphorylation 4/320 227/18722 0.545320772089328 0.61363437643603 PTPRC/CAV1/NEK6/FLT1 4 GO:0055088 lipid homeostasis 3/320 167/18722 0.546027968470622 0.614262882036648 CAV1/ABHD8/NPC2 3 GO:0001974 blood vessel remodeling 1/320 46/18722 0.547967202230671 0.614350379135153 FLNA 1 GO:0010830 regulation of myotube differentiation 1/320 46/18722 0.547967202230671 0.614350379135153 BHLHE41 1 GO:0032924 activin receptor signaling pathway 1/320 46/18722 0.547967202230671 0.614350379135153 TGFBR1 1 GO:0043462 regulation of ATPase activity 1/320 46/18722 0.547967202230671 0.614350379135153 PFN1 1 GO:0043616 keratinocyte proliferation 1/320 46/18722 0.547967202230671 0.614350379135153 ZFP36 1 GO:0044818 mitotic G2/M transition checkpoint 1/320 46/18722 0.547967202230671 0.614350379135153 CDK1 1 GO:0046839 phospholipid dephosphorylation 1/320 46/18722 0.547967202230671 0.614350379135153 PLPP3 1 GO:0048701 embryonic cranial skeleton morphogenesis 1/320 46/18722 0.547967202230671 0.614350379135153 TGFBR1 1 GO:0061462 protein localization to lysosome 1/320 46/18722 0.547967202230671 0.614350379135153 LAPTM5 1 GO:0070828 heterochromatin organization 1/320 46/18722 0.547967202230671 0.614350379135153 MBD3 1 GO:1900271 regulation of long-term synaptic potentiation 1/320 46/18722 0.547967202230671 0.614350379135153 TYROBP 1 GO:0021761 limbic system development 2/320 107/18722 0.548484643908417 0.614350379135153 NRP2/EZH2 2 GO:0036503 ERAD pathway 2/320 107/18722 0.548484643908417 0.614350379135153 CAV1/UBE2J1 2 GO:0042303 molting cycle 2/320 107/18722 0.548484643908417 0.614350379135153 CTNNB1/LGR5 2 GO:0042633 hair cycle 2/320 107/18722 0.548484643908417 0.614350379135153 CTNNB1/LGR5 2 GO:0051341 regulation of oxidoreductase activity 2/320 107/18722 0.548484643908417 0.614350379135153 CAV1/CYBA 2 GO:0043087 regulation of GTPase activity 6/320 348/18722 0.548699159297998 0.61442409924643 CCL3L3/CCL3/ITGB1/STMN1/IQGAP2/EZH2 6 GO:0071695 anatomical structure maturation 4/320 229/18722 0.552256730439193 0.618240262848752 KLF2/SNX10/RHOA/CTNNB1 4 GO:0007173 epidermal growth factor receptor signaling pathway 2/320 108/18722 0.553527504014129 0.618992055909711 NCF1/PLAUR 2 GO:0022037 metencephalon development 2/320 108/18722 0.553527504014129 0.618992055909711 AIF1/EZH2 2 GO:0033138 positive regulation of peptidyl-serine phosphorylation 2/320 108/18722 0.553527504014129 0.618992055909711 CAV1/TFRC 2 GO:0034440 lipid oxidation 2/320 108/18722 0.553527504014129 0.618992055909711 CROT/SLC27A2 2 GO:0000075 cell cycle checkpoint signaling 3/320 169/18722 0.554095090800526 0.619459122074614 PPP1R10/CDK1/SOX4 3 GO:0001754 eye photoreceptor cell differentiation 1/320 47/18722 0.555712463276194 0.620092870174786 RDH13 1 GO:0006998 nuclear envelope organization 1/320 47/18722 0.555712463276194 0.620092870174786 NEK6 1 GO:0007595 lactation 1/320 47/18722 0.555712463276194 0.620092870174786 CAV1 1 GO:0035315 hair cell differentiation 1/320 47/18722 0.555712463276194 0.620092870174786 CTNNB1 1 GO:0043114 regulation of vascular permeability 1/320 47/18722 0.555712463276194 0.620092870174786 PLEC 1 GO:0051972 regulation of telomerase activity 1/320 47/18722 0.555712463276194 0.620092870174786 CTNNB1 1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1/320 47/18722 0.555712463276194 0.620092870174786 HMOX1 1 GO:0016236 macroautophagy 5/320 291/18722 0.557718488665406 0.622163281632143 GAPDH/BNIP3L/HMOX1/UBA5/VPS13C 5 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 7/320 412/18722 0.559562910744095 0.624052347420945 CAV1/DDA1/UBE2J1/PSMD1/HSPA1A/PBK/CTNNB1 7 GO:0002673 regulation of acute inflammatory response 1/320 48/18722 0.563325422406133 0.626744458693714 HLA-E 1 GO:0002686 negative regulation of leukocyte migration 1/320 48/18722 0.563325422406133 0.626744458693714 HMOX1 1 GO:0015804 neutral amino acid transport 1/320 48/18722 0.563325422406133 0.626744458693714 SLC43A2 1 GO:0032527 protein exit from endoplasmic reticulum 1/320 48/18722 0.563325422406133 0.626744458693714 UBE2J1 1 GO:0042908 xenobiotic transport 1/320 48/18722 0.563325422406133 0.626744458693714 GJA1 1 GO:0045005 DNA-dependent DNA replication maintenance of fidelity 1/320 48/18722 0.563325422406133 0.626744458693714 SAMHD1 1 GO:0045912 negative regulation of carbohydrate metabolic process 1/320 48/18722 0.563325422406133 0.626744458693714 PLEK 1 GO:1903053 regulation of extracellular matrix organization 1/320 48/18722 0.563325422406133 0.626744458693714 TNFRSF1B 1 GO:0061387 regulation of extent of cell growth 2/320 110/18722 0.563493626342485 0.626744458693714 FN1/SEMA6D 2 GO:0090174 organelle membrane fusion 2/320 110/18722 0.563493626342485 0.626744458693714 CORO1A/ANXA1 2 GO:0007219 Notch signaling pathway 3/320 172/18722 0.566035008382929 0.629401683164225 KRT19/ANXA4/GALNT11 3 GO:0010948 negative regulation of cell cycle process 5/320 294/18722 0.566850476111675 0.630138866637999 ZFP36L2/PPP1R10/CDK1/EZH2/SOX4 5 GO:0006805 xenobiotic metabolic process 2/320 111/18722 0.568416672837174 0.631709976375256 CYP2J2/GSTO1 2 GO:0008206 bile acid metabolic process 1/320 49/18722 0.570808332593026 0.632157606613343 SLC27A2 1 GO:0009395 phospholipid catabolic process 1/320 49/18722 0.570808332593026 0.632157606613343 IDH1 1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 1/320 49/18722 0.570808332593026 0.632157606613343 TGFBR1 1 GO:0014075 response to amine 1/320 49/18722 0.570808332593026 0.632157606613343 CDK1 1 GO:0021695 cerebellar cortex development 1/320 49/18722 0.570808332593026 0.632157606613343 EZH2 1 GO:0042461 photoreceptor cell development 1/320 49/18722 0.570808332593026 0.632157606613343 RDH13 1 GO:0043330 response to exogenous dsRNA 1/320 49/18722 0.570808332593026 0.632157606613343 CAV1 1 GO:0043457 regulation of cellular respiration 1/320 49/18722 0.570808332593026 0.632157606613343 RHOA 1 GO:0051932 synaptic transmission, GABAergic 1/320 49/18722 0.570808332593026 0.632157606613343 EZH2 1 GO:0060964 regulation of gene silencing by miRNA 1/320 49/18722 0.570808332593026 0.632157606613343 ZFP36 1 GO:0060986 endocrine hormone secretion 1/320 49/18722 0.570808332593026 0.632157606613343 GJA1 1 GO:1901799 negative regulation of proteasomal protein catabolic process 1/320 49/18722 0.570808332593026 0.632157606613343 PBK 1 GO:1904752 regulation of vascular associated smooth muscle cell migration 1/320 49/18722 0.570808332593026 0.632157606613343 RHOA 1 GO:0010633 negative regulation of epithelial cell migration 2/320 112/18722 0.573299591119879 0.634746492633263 HMGB1/RHOA 2 GO:0050954 sensory perception of mechanical stimulus 3/320 175/18722 0.577778130798124 0.637569043015354 CXCR4/GPX1/LRP2 3 GO:0006220 pyrimidine nucleotide metabolic process 1/320 50/18722 0.578163408562084 0.637569043015354 UPP1 1 GO:0007632 visual behavior 1/320 50/18722 0.578163408562084 0.637569043015354 ITGB1 1 GO:0008089 anterograde axonal transport 1/320 50/18722 0.578163408562084 0.637569043015354 HSPB1 1 GO:0010665 regulation of cardiac muscle cell apoptotic process 1/320 50/18722 0.578163408562084 0.637569043015354 PPP1R10 1 GO:0042572 retinol metabolic process 1/320 50/18722 0.578163408562084 0.637569043015354 RDH13 1 GO:0043268 positive regulation of potassium ion transport 1/320 50/18722 0.578163408562084 0.637569043015354 FLNA 1 GO:0051646 mitochondrion localization 1/320 50/18722 0.578163408562084 0.637569043015354 ARMCX3 1 GO:0070231 T cell apoptotic process 1/320 50/18722 0.578163408562084 0.637569043015354 TSC22D3 1 GO:0071709 membrane assembly 1/320 50/18722 0.578163408562084 0.637569043015354 CAV1 1 GO:1901570 fatty acid derivative biosynthetic process 1/320 50/18722 0.578163408562084 0.637569043015354 PPT1 1 GO:1902930 regulation of alcohol biosynthetic process 1/320 50/18722 0.578163408562084 0.637569043015354 PLEK 1 GO:1903747 regulation of establishment of protein localization to mitochondrion 1/320 50/18722 0.578163408562084 0.637569043015354 BNIP3L 1 GO:1904036 negative regulation of epithelial cell apoptotic process 1/320 50/18722 0.578163408562084 0.637569043015354 HMOX1 1 GO:1904738 vascular associated smooth muscle cell migration 1/320 50/18722 0.578163408562084 0.637569043015354 RHOA 1 GO:0042254 ribosome biogenesis 5/320 299/18722 0.581854564076743 0.641468265412247 RPS27/RPS21/RPS17/RPS28/PA2G4 5 GO:0010874 regulation of cholesterol efflux 1/320 51/18722 0.585392827438484 0.643764752914838 CAV1 1 GO:0032964 collagen biosynthetic process 1/320 51/18722 0.585392827438484 0.643764752914838 VIM 1 GO:0045661 regulation of myoblast differentiation 1/320 51/18722 0.585392827438484 0.643764752914838 IGFBP3 1 GO:0046850 regulation of bone remodeling 1/320 51/18722 0.585392827438484 0.643764752914838 TFRC 1 GO:0048013 ephrin receptor signaling pathway 1/320 51/18722 0.585392827438484 0.643764752914838 EFNB1 1 GO:0051339 regulation of lyase activity 1/320 51/18722 0.585392827438484 0.643764752914838 TIMP2 1 GO:0060632 regulation of microtubule-based movement 1/320 51/18722 0.585392827438484 0.643764752914838 CCSAP 1 GO:0071622 regulation of granulocyte chemotaxis 1/320 51/18722 0.585392827438484 0.643764752914838 CD74 1 GO:1903307 positive regulation of regulated secretory pathway 1/320 51/18722 0.585392827438484 0.643764752914838 ITGB2 1 GO:0051648 vesicle localization 3/320 177/18722 0.585495629587116 0.643764752914838 RAB17/CTNNB1/PDCD6 3 GO:0034968 histone lysine methylation 2/320 115/18722 0.587706941522508 0.645852415524203 EZH2/CTNNB1 2 GO:0043279 response to alkaloid 2/320 115/18722 0.587706941522508 0.645852415524203 AIF1/CXCR4 2 GO:0035725 sodium ion transmembrane transport 3/320 178/18722 0.589320618187735 0.64734184810037 FXYD5/SLC6A8/FXYD3 3 GO:0032886 regulation of microtubule-based process 4/320 240/18722 0.589375612912292 0.64734184810037 CCSAP/STMN1/HSPA1A/RHOA 4 GO:0051056 regulation of small GTPase mediated signal transduction 5/320 302/18722 0.590723036339671 0.648649371819166 EPS8L1/ARHGDIB/TIMP2/ITGB1/STMN1 5 GO:0008286 insulin receptor signaling pathway 2/320 116/18722 0.592428780378449 0.649563478326763 IGF2/PTPRA 2 GO:0018107 peptidyl-threonine phosphorylation 2/320 116/18722 0.592428780378449 0.649563478326763 TGFBR1/CDK1 2 GO:0031123 RNA 3'-end processing 2/320 116/18722 0.592428780378449 0.649563478326763 RPS21/SSB 2 GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 1/320 52/18722 0.59249872938373 0.649563478326763 PLPP3 1 GO:0010662 regulation of striated muscle cell apoptotic process 1/320 52/18722 0.59249872938373 0.649563478326763 PPP1R10 1 GO:0060147 regulation of posttranscriptional gene silencing 1/320 52/18722 0.59249872938373 0.649563478326763 ZFP36 1 GO:0007033 vacuole organization 3/320 180/18722 0.596902495899525 0.654044315316053 CORO1A/LAPTM5/PPT1 3 GO:0071897 DNA biosynthetic process 3/320 180/18722 0.596902495899525 0.654044315316053 RFC3/CTNNB1/GJA1 3 GO:0043543 protein acylation 4/320 243/18722 0.599182796729821 0.654961569986875 MBD3/ISL1/MORF4L2/SOX4 4 GO:0001541 ovarian follicle development 1/320 53/18722 0.599483218221288 0.654961569986875 CEBPB 1 GO:0016925 protein sumoylation 1/320 53/18722 0.599483218221288 0.654961569986875 CTNNB1 1 GO:0031279 regulation of cyclase activity 1/320 53/18722 0.599483218221288 0.654961569986875 TIMP2 1 GO:0032210 regulation of telomere maintenance via telomerase 1/320 53/18722 0.599483218221288 0.654961569986875 CTNNB1 1 GO:0034381 plasma lipoprotein particle clearance 1/320 53/18722 0.599483218221288 0.654961569986875 HMOX1 1 GO:0045806 negative regulation of endocytosis 1/320 53/18722 0.599483218221288 0.654961569986875 CAV1 1 GO:0060966 regulation of gene silencing by RNA 1/320 53/18722 0.599483218221288 0.654961569986875 ZFP36 1 GO:0071320 cellular response to cAMP 1/320 53/18722 0.599483218221288 0.654961569986875 EZR 1 GO:0071715 icosanoid transport 1/320 53/18722 0.599483218221288 0.654961569986875 ANXA1 1 GO:0097479 synaptic vesicle localization 1/320 53/18722 0.599483218221288 0.654961569986875 CTNNB1 1 GO:0099504 synaptic vesicle cycle 3/320 181/18722 0.600659172847688 0.65607287925103 ACTG1/ACTB/CTNNB1 3 GO:0044782 cilium organization 6/320 368/18722 0.603331704035785 0.658817812123642 FLNA/RAB17/DYNLL1/GALNT11/SNX10/ACTR3 6 GO:0061138 morphogenesis of a branching epithelium 3/320 182/18722 0.604392877377285 0.659671256450093 CLIC4/MAGED1/CTNNB1 3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1/320 54/18722 0.606348362051658 0.659671256450093 HMOX1 1 GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1/320 54/18722 0.606348362051658 0.659671256450093 PTPRC 1 GO:0006584 catecholamine metabolic process 1/320 54/18722 0.606348362051658 0.659671256450093 ITGB2 1 GO:0009712 catechol-containing compound metabolic process 1/320 54/18722 0.606348362051658 0.659671256450093 ITGB2 1 GO:0010659 cardiac muscle cell apoptotic process 1/320 54/18722 0.606348362051658 0.659671256450093 PPP1R10 1 GO:0014888 striated muscle adaptation 1/320 54/18722 0.606348362051658 0.659671256450093 EZH2 1 GO:0035065 regulation of histone acetylation 1/320 54/18722 0.606348362051658 0.659671256450093 ISL1 1 GO:0043647 inositol phosphate metabolic process 1/320 54/18722 0.606348362051658 0.659671256450093 PLEK 1 GO:0060350 endochondral bone morphogenesis 1/320 54/18722 0.606348362051658 0.659671256450093 ANXA6 1 GO:0070839 metal ion export 1/320 54/18722 0.606348362051658 0.659671256450093 ATP2B1 1 GO:0072348 sulfur compound transport 1/320 54/18722 0.606348362051658 0.659671256450093 GJA1 1 GO:0072698 protein localization to microtubule cytoskeleton 1/320 54/18722 0.606348362051658 0.659671256450093 SNX10 1 GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II 1/320 54/18722 0.606348362051658 0.659671256450093 JUN 1 GO:0071901 negative regulation of protein serine/threonine kinase activity 2/320 120/18722 0.610912704591441 0.664287182992588 CAV1/PDCD4 2 GO:0072655 establishment of protein localization to mitochondrion 2/320 120/18722 0.610912704591441 0.664287182992588 TSPO/BNIP3L 2 GO:0003179 heart valve morphogenesis 1/320 55/18722 0.613096193857072 0.665435637777101 SOX4 1 GO:0044091 membrane biogenesis 1/320 55/18722 0.613096193857072 0.665435637777101 CAV1 1 GO:0046164 alcohol catabolic process 1/320 55/18722 0.613096193857072 0.665435637777101 TPI1 1 GO:0051898 negative regulation of protein kinase B signaling 1/320 55/18722 0.613096193857072 0.665435637777101 PDCD6 1 GO:0061098 positive regulation of protein tyrosine kinase activity 1/320 55/18722 0.613096193857072 0.665435637777101 NCF1 1 GO:0061614 pri-miRNA transcription by RNA polymerase II 1/320 55/18722 0.613096193857072 0.665435637777101 JUN 1 GO:1905517 macrophage migration 1/320 55/18722 0.613096193857072 0.665435637777101 CCL3 1 GO:0038127 ERBB signaling pathway 2/320 121/18722 0.615432892509016 0.667470133386851 NCF1/PLAUR 2 GO:0048706 embryonic skeletal system development 2/320 121/18722 0.615432892509016 0.667470133386851 TGFBR1/CTNNB1 2 GO:0140013 meiotic nuclear division 3/320 185/18722 0.615455277880906 0.667470133386851 ACTR3/TOP2A/CKS2 3 GO:0002090 regulation of receptor internalization 1/320 56/18722 0.619728712095983 0.670696447978156 CD63 1 GO:0010518 positive regulation of phospholipase activity 1/320 56/18722 0.619728712095983 0.670696447978156 FLT1 1 GO:0010658 striated muscle cell apoptotic process 1/320 56/18722 0.619728712095983 0.670696447978156 PPP1R10 1 GO:0030166 proteoglycan biosynthetic process 1/320 56/18722 0.619728712095983 0.670696447978156 CTNNB1 1 GO:0042733 embryonic digit morphogenesis 1/320 56/18722 0.619728712095983 0.670696447978156 CTNNB1 1 GO:0043470 regulation of carbohydrate catabolic process 1/320 56/18722 0.619728712095983 0.670696447978156 HMGB1 1 GO:0045599 negative regulation of fat cell differentiation 1/320 56/18722 0.619728712095983 0.670696447978156 ZFP36L2 1 GO:0048008 platelet-derived growth factor receptor signaling pathway 1/320 56/18722 0.619728712095983 0.670696447978156 TXNIP 1 GO:0072329 monocarboxylic acid catabolic process 2/320 122/18722 0.619912828211101 0.670720033036991 CROT/SLC27A2 2 GO:0018205 peptidyl-lysine modification 6/320 376/18722 0.624161164173425 0.674963080440877 MBD3/ISL1/MORF4L2/EZH2/CTNNB1/SOX4 6 GO:0044282 small molecule catabolic process 6/320 376/18722 0.624161164173425 0.674963080440877 CROT/UPP1/APOBEC3A/TPI1/ENO1/SLC27A2 6 GO:0006695 cholesterol biosynthetic process 1/320 57/18722 0.626247881287523 0.675804712844096 DHCR24 1 GO:0010883 regulation of lipid storage 1/320 57/18722 0.626247881287523 0.675804712844096 PLIN2 1 GO:0030219 megakaryocyte differentiation 1/320 57/18722 0.626247881287523 0.675804712844096 UBA5 1 GO:0051155 positive regulation of striated muscle cell differentiation 1/320 57/18722 0.626247881287523 0.675804712844096 MORF4L2 1 GO:0051785 positive regulation of nuclear division 1/320 57/18722 0.626247881287523 0.675804712844096 IGF2 1 GO:0060042 retina morphogenesis in camera-type eye 1/320 57/18722 0.626247881287523 0.675804712844096 RDH13 1 GO:0097120 receptor localization to synapse 1/320 57/18722 0.626247881287523 0.675804712844096 TYROBP 1 GO:1902653 secondary alcohol biosynthetic process 1/320 57/18722 0.626247881287523 0.675804712844096 DHCR24 1 GO:0061448 connective tissue development 4/320 252/18722 0.627749284303353 0.677248052935106 ARRDC3/TGFBR1/ANXA6/CTNNB1 4 GO:0018105 peptidyl-serine phosphorylation 5/320 315/18722 0.627928351956197 0.677264408844428 CAV1/NEK6/TGFBR1/CDK1/TFRC 5 GO:0001954 positive regulation of cell-matrix adhesion 1/320 58/18722 0.632655632586102 0.68040944139661 PLEKHA2 1 GO:0007131 reciprocal meiotic recombination 1/320 58/18722 0.632655632586102 0.68040944139661 TOP2A 1 GO:0007405 neuroblast proliferation 1/320 58/18722 0.632655632586102 0.68040944139661 CTNNB1 1 GO:0009161 ribonucleoside monophosphate metabolic process 1/320 58/18722 0.632655632586102 0.68040944139661 UPP1 1 GO:0010559 regulation of glycoprotein biosynthetic process 1/320 58/18722 0.632655632586102 0.68040944139661 CTNNB1 1 GO:0010574 regulation of vascular endothelial growth factor production 1/320 58/18722 0.632655632586102 0.68040944139661 ISL1 1 GO:0018208 peptidyl-proline modification 1/320 58/18722 0.632655632586102 0.68040944139661 P4HA1 1 GO:0032387 negative regulation of intracellular transport 1/320 58/18722 0.632655632586102 0.68040944139661 UBE2J1 1 GO:0043506 regulation of JUN kinase activity 1/320 58/18722 0.632655632586102 0.68040944139661 PDCD4 1 GO:0044380 protein localization to cytoskeleton 1/320 58/18722 0.632655632586102 0.68040944139661 SNX10 1 GO:0140527 reciprocal homologous recombination 1/320 58/18722 0.632655632586102 0.68040944139661 TOP2A 1 GO:0051053 negative regulation of DNA metabolic process 2/320 125/18722 0.633111681948288 0.680722734793215 PARP1/GJA1 2 GO:0051216 cartilage development 3/320 190/18722 0.633425824997186 0.680883326974083 TGFBR1/ANXA6/CTNNB1 3 GO:0006839 mitochondrial transport 4/320 254/18722 0.633919099596492 0.681236337979897 TSPO/BNIP3L/PMAIP1/HSPA1A 4 GO:0043547 positive regulation of GTPase activity 4/320 255/18722 0.636979286884692 0.684346961364417 CCL3L3/CCL3/ITGB1/EZH2 4 GO:0002820 negative regulation of adaptive immune response 1/320 59/18722 0.638953864346307 0.685577088413124 PTPRC 1 GO:0032768 regulation of monooxygenase activity 1/320 59/18722 0.638953864346307 0.685577088413124 CAV1 1 GO:0051353 positive regulation of oxidoreductase activity 1/320 59/18722 0.638953864346307 0.685577088413124 CYBA 1 GO:0051568 histone H3-K4 methylation 1/320 59/18722 0.638953864346307 0.685577088413124 CTNNB1 1 GO:2000351 regulation of endothelial cell apoptotic process 1/320 59/18722 0.638953864346307 0.685577088413124 PDCD4 1 GO:0007018 microtubule-based movement 6/320 382/18722 0.639367538437345 0.685842852757816 ARMCX3/CCSAP/CDC42/DST/ACTR3/HSPB1 6 GO:0090596 sensory organ morphogenesis 4/320 256/18722 0.640022916869963 0.686367685571422 RDH13/FBN1/C12orf57/CTNNB1 4 GO:0016042 lipid catabolic process 5/320 320/18722 0.641685145644834 0.687820814547701 CROT/CYP19A1/SLC27A2/PPT1/IDH1 5 GO:0051224 negative regulation of protein transport 2/320 127/18722 0.641710851907403 0.687820814547701 ANXA1/UBE2J1 2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 1/320 60/18722 0.645144442678256 0.689890485803974 TRA2B 1 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 1/320 60/18722 0.645144442678256 0.689890485803974 HSPA1A 1 GO:0006289 nucleotide-excision repair 1/320 60/18722 0.645144442678256 0.689890485803974 HMGB1 1 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 1/320 60/18722 0.645144442678256 0.689890485803974 CDK1 1 GO:0030071 regulation of mitotic metaphase/anaphase transition 1/320 60/18722 0.645144442678256 0.689890485803974 NEK6 1 GO:0033866 nucleoside bisphosphate biosynthetic process 1/320 60/18722 0.645144442678256 0.689890485803974 PPT1 1 GO:0034030 ribonucleoside bisphosphate biosynthetic process 1/320 60/18722 0.645144442678256 0.689890485803974 PPT1 1 GO:0034033 purine nucleoside bisphosphate biosynthetic process 1/320 60/18722 0.645144442678256 0.689890485803974 PPT1 1 GO:0035825 homologous recombination 1/320 60/18722 0.645144442678256 0.689890485803974 TOP2A 1 GO:0006639 acylglycerol metabolic process 2/320 128/18722 0.645950683440569 0.690038320573018 CAV1/GPX1 2 GO:0033865 nucleoside bisphosphate metabolic process 2/320 128/18722 0.645950683440569 0.690038320573018 CROT/PPT1 2 GO:0033875 ribonucleoside bisphosphate metabolic process 2/320 128/18722 0.645950683440569 0.690038320573018 CROT/PPT1 2 GO:0034032 purine nucleoside bisphosphate metabolic process 2/320 128/18722 0.645950683440569 0.690038320573018 CROT/PPT1 2 GO:0006638 neutral lipid metabolic process 2/320 129/18722 0.650150817689624 0.694166196044838 CAV1/GPX1 2 GO:0007127 meiosis I 2/320 129/18722 0.650150817689624 0.694166196044838 TOP2A/CKS2 2 GO:0006900 vesicle budding from membrane 1/320 61/18722 0.651229201993601 0.694599654785121 PDCD6 1 GO:0019748 secondary metabolic process 1/320 61/18722 0.651229201993601 0.694599654785121 ZEB2 1 GO:0050994 regulation of lipid catabolic process 1/320 61/18722 0.651229201993601 0.694599654785121 IDH1 1 GO:0060997 dendritic spine morphogenesis 1/320 61/18722 0.651229201993601 0.694599654785121 CDC42 1 GO:0001763 morphogenesis of a branching structure 3/320 196/18722 0.654212084874627 0.697167244609354 CLIC4/MAGED1/CTNNB1 3 GO:0006352 DNA-templated transcription, initiation 2/320 130/18722 0.654311368488643 0.697167244609354 HMGB1/JUN 2 GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 2/320 130/18722 0.654311368488643 0.697167244609354 TMED4/PDCD6 2 GO:0007098 centrosome cycle 2/320 130/18722 0.654311368488643 0.697167244609354 CDK1/CTNNB1 2 GO:0051321 meiotic cell cycle 4/320 261/18722 0.654990918864465 0.697711388695017 MYH9/ACTR3/TOP2A/CKS2 4 GO:0007062 sister chromatid cohesion 1/320 62/18722 0.657209945542288 0.69899394980199 CTNNB1 1 GO:0007091 metaphase/anaphase transition of mitotic cell cycle 1/320 62/18722 0.657209945542288 0.69899394980199 NEK6 1 GO:0007588 excretion 1/320 62/18722 0.657209945542288 0.69899394980199 HMOX1 1 GO:0010573 vascular endothelial growth factor production 1/320 62/18722 0.657209945542288 0.69899394980199 ISL1 1 GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 1/320 62/18722 0.657209945542288 0.69899394980199 TGFBR1 1 GO:1902750 negative regulation of cell cycle G2/M phase transition 1/320 62/18722 0.657209945542288 0.69899394980199 CDK1 1 GO:0018022 peptidyl-lysine methylation 2/320 131/18722 0.658432457366233 0.699933860004444 EZH2/CTNNB1 2 GO:1904950 negative regulation of establishment of protein localization 2/320 131/18722 0.658432457366233 0.699933860004444 ANXA1/UBE2J1 2 GO:0045667 regulation of osteoblast differentiation 2/320 132/18722 0.66251421325096 0.704091751325351 CTNNB1/CEBPB 2 GO:0099601 regulation of neurotransmitter receptor activity 1/320 63/18722 0.663088445940276 0.704339706587461 IFNGR2 1 GO:1902099 regulation of metaphase/anaphase transition of cell cycle 1/320 63/18722 0.663088445940276 0.704339706587461 NEK6 1 GO:0006323 DNA packaging 3/320 199/18722 0.664284774343736 0.705429115288696 HMGB1/CDK1/TOP2A 3 GO:0009855 determination of bilateral symmetry 2/320 133/18722 0.666556772184556 0.707659964713922 GALNT11/CTNNB1 2 GO:0099003 vesicle-mediated transport in synapse 3/320 200/18722 0.667594769549624 0.708579909524543 ACTG1/ACTB/CTNNB1 3 GO:0016126 sterol biosynthetic process 1/320 64/18722 0.66886644568834 0.708655423995954 DHCR24 1 GO:0017156 calcium-ion regulated exocytosis 1/320 64/18722 0.66886644568834 0.708655423995954 MYH9 1 GO:0030858 positive regulation of epithelial cell differentiation 1/320 64/18722 0.66886644568834 0.708655423995954 CTNNB1 1 GO:0046530 photoreceptor cell differentiation 1/320 64/18722 0.66886644568834 0.708655423995954 RDH13 1 GO:0046888 negative regulation of hormone secretion 1/320 64/18722 0.66886644568834 0.708655423995954 GJA1 1 GO:0050771 negative regulation of axonogenesis 1/320 64/18722 0.66886644568834 0.708655423995954 SEMA6D 1 GO:1903018 regulation of glycoprotein metabolic process 1/320 64/18722 0.66886644568834 0.708655423995954 CTNNB1 1 GO:0009799 specification of symmetry 2/320 134/18722 0.670560277042705 0.710267896626623 GALNT11/CTNNB1 2 GO:0034470 ncRNA processing 6/320 395/18722 0.671036829638423 0.710590512574567 RPS27/RPS21/RPS17/RPS28/SSB/PA2G4 6 GO:0000819 sister chromatid segregation 3/320 202/18722 0.674143400578963 0.712116161865731 NEK6/CTNNB1/TOP2A 3 GO:0009581 detection of external stimulus 2/320 135/18722 0.674524877263246 0.712116161865731 CXCR4/CTNNB1 2 GO:0042157 lipoprotein metabolic process 2/320 135/18722 0.674524877263246 0.712116161865731 DBI/PPT1 2 GO:0061982 meiosis I cell cycle process 2/320 135/18722 0.674524877263246 0.712116161865731 TOP2A/CKS2 2 GO:0010965 regulation of mitotic sister chromatid separation 1/320 65/18722 0.674545657682108 0.712116161865731 NEK6 1 GO:0035418 protein localization to synapse 1/320 65/18722 0.674545657682108 0.712116161865731 HSPB1 1 GO:0038034 signal transduction in absence of ligand 1/320 65/18722 0.674545657682108 0.712116161865731 HSPA1A 1 GO:0044784 metaphase/anaphase transition of cell cycle 1/320 65/18722 0.674545657682108 0.712116161865731 NEK6 1 GO:0060389 pathway-restricted SMAD protein phosphorylation 1/320 65/18722 0.674545657682108 0.712116161865731 TGFBR1 1 GO:0061512 protein localization to cilium 1/320 65/18722 0.674545657682108 0.712116161865731 SNX10 1 GO:0072577 endothelial cell apoptotic process 1/320 65/18722 0.674545657682108 0.712116161865731 PDCD4 1 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 1/320 65/18722 0.674545657682108 0.712116161865731 HSPA1A 1 GO:0006643 membrane lipid metabolic process 3/320 203/18722 0.677382048295028 0.714927873194139 PSAP/PLPP3/PPT1 3 GO:0030193 regulation of blood coagulation 1/320 66/18722 0.680127765713503 0.717276142911739 CAV1 1 GO:0032715 negative regulation of interleukin-6 production 1/320 66/18722 0.680127765713503 0.717276142911739 KLF2 1 GO:0046626 regulation of insulin receptor signaling pathway 1/320 66/18722 0.680127765713503 0.717276142911739 IGF2 1 GO:0016570 histone modification 7/320 463/18722 0.681015844357884 0.718029463864959 IGF2/MBD3/ISL1/MORF4L2/CDK1/EZH2/CTNNB1 7 GO:0000086 G2/M transition of mitotic cell cycle 2/320 137/18722 0.682337992773401 0.718689927642033 BACH1/CDK1 2 GO:0006986 response to unfolded protein 2/320 137/18722 0.682337992773401 0.718689927642033 HSPA1A/HSPB1 2 GO:0007586 digestion 2/320 137/18722 0.682337992773401 0.718689927642033 EZR/SNX10 2 GO:0090090 negative regulation of canonical Wnt signaling pathway 2/320 137/18722 0.682337992773401 0.718689927642033 CAV1/ISL1 2 GO:0006513 protein monoubiquitination 1/320 67/18722 0.6856144249637 0.721221691433301 PDCD6 1 GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 1/320 67/18722 0.6856144249637 0.721221691433301 ANXA1 1 GO:0043967 histone H4 acetylation 1/320 67/18722 0.6856144249637 0.721221691433301 MORF4L2 1 GO:0048814 regulation of dendrite morphogenesis 1/320 67/18722 0.6856144249637 0.721221691433301 ID1 1 GO:0051306 mitotic sister chromatid separation 1/320 67/18722 0.6856144249637 0.721221691433301 NEK6 1 GO:0009582 detection of abiotic stimulus 2/320 138/18722 0.686186837403717 0.721272961626089 CXCR4/CTNNB1 2 GO:0035107 appendage morphogenesis 2/320 138/18722 0.686186837403717 0.721272961626089 CTNNB1/SOX4 2 GO:0035108 limb morphogenesis 2/320 138/18722 0.686186837403717 0.721272961626089 CTNNB1/SOX4 2 GO:0042987 amyloid precursor protein catabolic process 1/320 68/18722 0.691007262487774 0.725970508161577 DHCR24 1 GO:1900046 regulation of hemostasis 1/320 68/18722 0.691007262487774 0.725970508161577 CAV1 1 GO:0007004 telomere maintenance via telomerase 1/320 69/18722 0.696307877691158 0.730796075849597 CTNNB1 1 GO:0019226 transmission of nerve impulse 1/320 69/18722 0.696307877691158 0.730796075849597 PLEC 1 GO:0031060 regulation of histone methylation 1/320 69/18722 0.696307877691158 0.730796075849597 CTNNB1 1 GO:0050810 regulation of steroid biosynthetic process 1/320 69/18722 0.696307877691158 0.730796075849597 TSPO 1 GO:0016571 histone methylation 2/320 141/18722 0.697504611346656 0.73186618945769 EZH2/CTNNB1 2 GO:0007281 germ cell development 4/320 278/18722 0.70271420353163 0.737145237114165 DYNLL1/UBE2J1/CTNNB1/LGR5 4 GO:0031023 microtubule organizing center organization 2/320 143/18722 0.704861007010954 0.739209563697782 CDK1/CTNNB1 2 GO:0030258 lipid modification 3/320 212/18722 0.705463150255226 0.739653320693883 CROT/SLC27A2/PLPP3 3 GO:0008344 adult locomotory behavior 1/320 71/18722 0.706638703311914 0.740510048715402 PPT1 1 GO:0050818 regulation of coagulation 1/320 71/18722 0.706638703311914 0.740510048715402 CAV1 1 GO:0001505 regulation of neurotransmitter levels 3/320 213/18722 0.708465297560214 0.741878450400586 ITGB1/STXBP2/PPT1 3 GO:0031644 regulation of nervous system process 2/320 144/18722 0.70848314745419 0.741878450400586 TNFRSF1B/CCL3 2 GO:0033135 regulation of peptidyl-serine phosphorylation 2/320 144/18722 0.70848314745419 0.741878450400586 CAV1/TFRC 2 GO:0006470 protein dephosphorylation 4/320 281/18722 0.710623281325631 0.743930934491388 PTPRC/PTP4A2/SLC39A10/PTPRA 4 GO:0033045 regulation of sister chromatid segregation 1/320 72/18722 0.711671978468216 0.744462940514093 NEK6 1 GO:0050709 negative regulation of protein secretion 1/320 72/18722 0.711671978468216 0.744462940514093 ANXA1 1 GO:1905818 regulation of chromosome separation 1/320 72/18722 0.711671978468216 0.744462940514093 NEK6 1 GO:0007269 neurotransmitter secretion 2/320 145/18722 0.712068183731801 0.744500439063716 STXBP2/PPT1 2 GO:0099643 signal release from synapse 2/320 145/18722 0.712068183731801 0.744500439063716 STXBP2/PPT1 2 GO:0032456 endocytic recycling 1/320 73/18722 0.716619161679485 0.748690360571336 RAB17 1 GO:0051937 catecholamine transport 1/320 73/18722 0.716619161679485 0.748690360571336 ACTB 1 GO:0070988 demethylation 1/320 73/18722 0.716619161679485 0.748690360571336 APOBEC3A 1 GO:0016311 dephosphorylation 6/320 417/18722 0.720470349748219 0.752523631233478 PTPRC/PLEK/PTP4A2/SLC39A10/PTPRA/PLPP3 6 GO:0046323 glucose import 1/320 74/18722 0.721481720972883 0.75281880582322 SLC2A3 1 GO:0046470 phosphatidylcholine metabolic process 1/320 74/18722 0.721481720972883 0.75281880582322 DBI 1 GO:0070972 protein localization to endoplasmic reticulum 1/320 74/18722 0.721481720972883 0.75281880582322 GJA1 1 GO:1901568 fatty acid derivative metabolic process 1/320 74/18722 0.721481720972883 0.75281880582322 PPT1 1 GO:0044839 cell cycle G2/M phase transition 2/320 148/18722 0.722602742880056 0.753798165508809 BACH1/CDK1 2 GO:0006278 RNA-dependent DNA biosynthetic process 1/320 75/18722 0.726261099420366 0.75742323644749 CTNNB1 1 GO:0022618 ribonucleoprotein complex assembly 3/320 220/18722 0.72882675052875 0.759523867133618 RPS27/RPS28/EIF4H 3 GO:0031503 protein-containing complex localization 3/320 220/18722 0.72882675052875 0.759523867133618 TYROBP/EZR/SSB 3 GO:0048705 skeletal system morphogenesis 3/320 220/18722 0.72882675052875 0.759523867133618 TGFBR1/ANXA6/CTNNB1 3 GO:0009123 nucleoside monophosphate metabolic process 1/320 76/18722 0.730958715561595 0.761169710862023 UPP1 1 GO:0032720 negative regulation of tumor necrosis factor production 1/320 76/18722 0.730958715561595 0.761169710862023 TSPO 1 GO:0071426 ribonucleoprotein complex export from nucleus 1/320 76/18722 0.730958715561595 0.761169710862023 SSB 1 GO:0055067 monovalent inorganic cation homeostasis 2/320 151/18722 0.732810986691777 0.762906272867327 CLIC4/PPT1 2 GO:0015931 nucleobase-containing compound transport 3/320 222/18722 0.734435987513961 0.76440541571982 ZFP36/SSB/GJA1 3 GO:0000380 alternative mRNA splicing, via spliceosome 1/320 77/18722 0.735575963819682 0.765013813869349 TRA2B 1 GO:0006367 transcription initiation from RNA polymerase II promoter 1/320 77/18722 0.735575963819682 0.765013813869349 HMGB1 1 GO:0071166 ribonucleoprotein complex localization 1/320 77/18722 0.735575963819682 0.765013813869349 SSB 1 GO:0008643 carbohydrate transport 2/320 152/18722 0.736142252676886 0.765217556744879 SLC2A3/EZR 2 GO:0090501 RNA phosphodiester bond hydrolysis 2/320 152/18722 0.736142252676886 0.765217556744879 RPS21/SAMHD1 2 GO:0035050 embryonic heart tube development 1/320 78/18722 0.740114214909931 0.768572992211067 CTNNB1 1 GO:0061045 negative regulation of wound healing 1/320 78/18722 0.740114214909931 0.768572992211067 GJA1 1 GO:1901616 organic hydroxy compound catabolic process 1/320 78/18722 0.740114214909931 0.768572992211067 TPI1 1 GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 1/320 78/18722 0.740114214909931 0.768572992211067 TSPO 1 GO:0007605 sensory perception of sound 2/320 154/18722 0.742698928822418 0.770869624188453 GPX1/LRP2 2 GO:0050770 regulation of axonogenesis 2/320 154/18722 0.742698928822418 0.770869624188453 FN1/SEMA6D 2 GO:0006029 proteoglycan metabolic process 1/320 79/18722 0.744574816241664 0.772428606756353 CTNNB1 1 GO:0050772 positive regulation of axonogenesis 1/320 79/18722 0.744574816241664 0.772428606756353 FN1 1 GO:0006486 protein glycosylation 3/320 226/18722 0.745380219218038 0.772876051645906 GALNT11/UBE2J1/TUSC3 3 GO:0043413 macromolecule glycosylation 3/320 226/18722 0.745380219218038 0.772876051645906 GALNT11/UBE2J1/TUSC3 3 GO:0071826 ribonucleoprotein complex subunit organization 3/320 227/18722 0.748059586813512 0.775459661995342 RPS27/RPS28/EIF4H 3 GO:0021766 hippocampus development 1/320 80/18722 0.748959092313254 0.776002750611426 EZH2 1 GO:0051303 establishment of chromosome localization 1/320 80/18722 0.748959092313254 0.776002750611426 ACTR3 1 GO:0060968 regulation of gene silencing 1/320 81/18722 0.753268345100496 0.780076391467481 ZFP36 1 GO:2000243 positive regulation of reproductive process 1/320 81/18722 0.753268345100496 0.780076391467481 CTNNB1 1 GO:0007032 endosome organization 1/320 82/18722 0.757503854438399 0.78348083267571 SNX10 1 GO:0008543 fibroblast growth factor receptor signaling pathway 1/320 82/18722 0.757503854438399 0.78348083267571 CTNNB1 1 GO:0016575 histone deacetylation 1/320 82/18722 0.757503854438399 0.78348083267571 MORF4L2 1 GO:0050000 chromosome localization 1/320 82/18722 0.757503854438399 0.78348083267571 ACTR3 1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic 1/320 82/18722 0.757503854438399 0.78348083267571 RPS21 1 GO:0035966 response to topologically incorrect protein 2/320 159/18722 0.75848407818858 0.784298351119923 HSPA1A/HSPB1 2 GO:0006405 RNA export from nucleus 1/320 84/18722 0.765758653648059 0.791028689218445 SSB 1 GO:0009953 dorsal/ventral pattern formation 1/320 84/18722 0.765758653648059 0.791028689218445 CTNNB1 1 GO:0015844 monoamine transport 1/320 84/18722 0.765758653648059 0.791028689218445 ACTB 1 GO:0097061 dendritic spine organization 1/320 84/18722 0.765758653648059 0.791028689218445 CDC42 1 GO:0060021 roof of mouth development 1/320 85/18722 0.769780395832447 0.794587208488551 TGFBR1 1 GO:0097006 regulation of plasma lipoprotein particle levels 1/320 85/18722 0.769780395832447 0.794587208488551 HMOX1 1 GO:0097194 execution phase of apoptosis 1/320 85/18722 0.769780395832447 0.794587208488551 TOP2A 1 GO:0050657 nucleic acid transport 2/320 163/18722 0.770504219465637 0.794937187223973 ZFP36/SSB 2 GO:0050658 RNA transport 2/320 163/18722 0.770504219465637 0.794937187223973 ZFP36/SSB 2 GO:0000209 protein polyubiquitination 3/320 236/18722 0.771171183772128 0.795426692797413 DDA1/UBE2J1/CTNNB1 3 GO:0006493 protein O-linked glycosylation 1/320 86/18722 0.77373329991216 0.797472186389884 GALNT11 1 GO:0034103 regulation of tissue remodeling 1/320 86/18722 0.77373329991216 0.797472186389884 TFRC 1 GO:0045921 positive regulation of exocytosis 1/320 86/18722 0.77373329991216 0.797472186389884 ITGB2 1 GO:0007286 spermatid development 2/320 165/18722 0.776317047295735 0.799935670679795 DYNLL1/UBE2J1 2 GO:0051236 establishment of RNA localization 2/320 166/18722 0.779175026069569 0.802680430745315 ZFP36/SSB 2 GO:0070085 glycosylation 3/320 240/18722 0.7808748985968 0.804231077019436 GALNT11/UBE2J1/TUSC3 3 GO:0050829 defense response to Gram-negative bacterium 1/320 88/18722 0.781437272319998 0.804609720714237 LYZ 1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 2/320 167/18722 0.782001051010162 0.804789126469238 ITGB1/EMB 2 GO:0009451 RNA modification 2/320 167/18722 0.782001051010162 0.804789126469238 APOBEC3A/SSB 2 GO:0071824 protein-DNA complex subunit organization 3/320 241/18722 0.783247353097927 0.805871031623664 RPL23/HMGB1/GMNN 3 GO:0046394 carboxylic acid biosynthetic process 4/320 314/18722 0.787607572796794 0.81015546198565 ANXA1/CD74/SLC27A2/GPX4 4 GO:0006400 tRNA modification 1/320 90/18722 0.788879730206499 0.810858468958521 SSB 1 GO:0035278 miRNA mediated inhibition of translation 1/320 90/18722 0.788879730206499 0.810858468958521 ZFP36 1 GO:0040033 negative regulation of translation, ncRNA-mediated 1/320 90/18722 0.788879730206499 0.810858468958521 ZFP36 1 GO:0030178 negative regulation of Wnt signaling pathway 2/320 170/18722 0.790289938524404 0.812105950256861 CAV1/ISL1 2 GO:0016053 organic acid biosynthetic process 4/320 316/18722 0.791699227925046 0.813149691719187 ANXA1/CD74/SLC27A2/GPX4 4 GO:0043414 macromolecule methylation 4/320 316/18722 0.791699227925046 0.813149691719187 MBD3/PARP1/EZH2/CTNNB1 4 GO:0045974 regulation of translation, ncRNA-mediated 1/320 91/18722 0.792505668717336 0.813392744736977 ZFP36 1 GO:0006814 sodium ion transport 3/320 245/18722 0.792526425535109 0.813392744736977 FXYD5/SLC6A8/FXYD3 3 GO:0017148 negative regulation of translation 3/320 245/18722 0.792526425535109 0.813392744736977 GAPDH/ZFP36/ZFP36L2 3 GO:0048469 cell maturation 2/320 171/18722 0.792990686954119 0.813667126519598 KLF2/CTNNB1 2 GO:0009101 glycoprotein biosynthetic process 4/320 317/18722 0.793721340930566 0.814214642682498 GALNT11/UBE2J1/CTNNB1/TUSC3 4 GO:0009100 glycoprotein metabolic process 5/320 387/18722 0.794182089596093 0.814485081710364 GALNT11/UBE2J1/CTSL/CTNNB1/TUSC3 5 GO:0048515 spermatid differentiation 2/320 172/18722 0.795660753760839 0.815394403407685 DYNLL1/UBE2J1 2 GO:0048736 appendage development 2/320 172/18722 0.795660753760839 0.815394403407685 CTNNB1/SOX4 2 GO:0060173 limb development 2/320 172/18722 0.795660753760839 0.815394403407685 CTNNB1/SOX4 2 GO:0006497 protein lipidation 1/320 92/18722 0.796069523905488 0.815611027219806 DBI 1 GO:0060349 bone morphogenesis 1/320 93/18722 0.799572355486285 0.818793797489301 ANXA6 1 GO:0106027 neuron projection organization 1/320 93/18722 0.799572355486285 0.818793797489301 CDC42 1 GO:0010389 regulation of G2/M transition of mitotic cell cycle 1/320 94/18722 0.803015205142433 0.821889872103131 CDK1 1 GO:1903035 negative regulation of response to wounding 1/320 94/18722 0.803015205142433 0.821889872103131 GJA1 1 GO:0046486 glycerolipid metabolic process 5/320 392/18722 0.803192474238249 0.821889872103131 PLEK/CAV1/GPX1/DBI/ABHD8 5 GO:0008593 regulation of Notch signaling pathway 1/320 95/18722 0.806399096829916 0.824694750698896 GALNT11 1 GO:0042982 amyloid precursor protein metabolic process 1/320 95/18722 0.806399096829916 0.824694750698896 DHCR24 1 GO:0022613 ribonucleoprotein complex biogenesis 6/320 463/18722 0.806532305802091 0.824694750698896 RPS27/RPS21/RPS17/RPS28/EIF4H/PA2G4 6 GO:0006637 acyl-CoA metabolic process 1/320 96/18722 0.809725037078717 0.826731863901472 PPT1 1 GO:0034620 cellular response to unfolded protein 1/320 96/18722 0.809725037078717 0.826731863901472 HSPA1A 1 GO:0035282 segmentation 1/320 96/18722 0.809725037078717 0.826731863901472 NRP2 1 GO:0035383 thioester metabolic process 1/320 96/18722 0.809725037078717 0.826731863901472 PPT1 1 GO:0042158 lipoprotein biosynthetic process 1/320 96/18722 0.809725037078717 0.826731863901472 DBI 1 GO:0043648 dicarboxylic acid metabolic process 1/320 96/18722 0.809725037078717 0.826731863901472 IDH1 1 GO:0008654 phospholipid biosynthetic process 3/320 253/18722 0.810095858190383 0.826906147737812 ABHD8/ISYNA1/IDH1 3 GO:0007626 locomotory behavior 2/320 179/18722 0.813513643823462 0.830189769394553 ARRDC3/PPT1 2 GO:0006479 protein methylation 2/320 181/18722 0.818352932857918 0.834715951263619 EZH2/CTNNB1 2 GO:0008213 protein alkylation 2/320 181/18722 0.818352932857918 0.834715951263619 EZH2/CTNNB1 2 GO:0007631 feeding behavior 1/320 99/18722 0.819364959276486 0.835129751290192 NPB 1 GO:0060291 long-term synaptic potentiation 1/320 99/18722 0.819364959276486 0.835129751290192 TYROBP 1 GO:0060996 dendritic spine development 1/320 99/18722 0.819364959276486 0.835129751290192 CDC42 1 GO:0006910 phagocytosis, recognition 1/320 100/18722 0.822468820793509 0.837673445284392 FCN1 1 GO:0019218 regulation of steroid metabolic process 1/320 100/18722 0.822468820793509 0.837673445284392 TSPO 1 GO:0051588 regulation of neurotransmitter transport 1/320 100/18722 0.822468820793509 0.837673445284392 ITGB1 1 GO:0048024 regulation of mRNA splicing, via spliceosome 1/320 101/18722 0.825519512306025 0.840366253966124 TRA2B 1 GO:0051963 regulation of synapse assembly 1/320 101/18722 0.825519512306025 0.840366253966124 RAB17 1 GO:0090305 nucleic acid phosphodiester bond hydrolysis 3/320 261/18722 0.826395987714822 0.841051286019125 RPS21/ZFP36/SAMHD1 3 GO:0006672 ceramide metabolic process 1/320 102/18722 0.828517941824423 0.842795700546163 PLPP3 1 GO:1902749 regulation of cell cycle G2/M phase transition 1/320 102/18722 0.828517941824423 0.842795700546163 CDK1 1 GO:0030148 sphingolipid biosynthetic process 1/320 103/18722 0.83146500190048 0.845585377271174 PLPP3 1 GO:0032006 regulation of TOR signaling 1/320 104/18722 0.83436156988973 0.848113654805501 PDCD6 1 GO:1901890 positive regulation of cell junction assembly 1/320 104/18722 0.83436156988973 0.848113654805501 CAV1 1 GO:0034660 ncRNA metabolic process 6/320 485/18722 0.839709982764143 0.853222108675923 RPS27/RPS21/RPS17/RPS28/SSB/PA2G4 6 GO:0001824 blastocyst development 1/320 106/18722 0.840006664591882 0.853222108675923 TGFBR1 1 GO:0007218 neuropeptide signaling pathway 1/320 106/18722 0.840006664591882 0.853222108675923 NPB 1 GO:0032526 response to retinoic acid 1/320 107/18722 0.842756872334179 0.855805209261447 GJA1 1 GO:0098659 inorganic cation import across plasma membrane 1/320 108/18722 0.845459950542777 0.858128350686012 SLC39A10 1 GO:0099587 inorganic ion import across plasma membrane 1/320 108/18722 0.845459950542777 0.858128350686012 SLC39A10 1 GO:0034249 negative regulation of cellular amide metabolic process 3/320 273/18722 0.848600739335301 0.861104679502324 GAPDH/ZFP36/ZFP36L2 3 GO:1904659 glucose transmembrane transport 1/320 110/18722 0.850727925274019 0.863051261289527 SLC2A3 1 GO:0001578 microtubule bundle formation 1/320 113/18722 0.858296103990673 0.870515341602715 CAPN6 1 GO:0008645 hexose transmembrane transport 1/320 114/18722 0.860732841414661 0.872505198069856 SLC2A3 1 GO:0006403 RNA localization 2/320 201/18722 0.860891503516652 0.872505198069856 ZFP36/SSB 2 GO:0065004 protein-DNA complex assembly 2/320 201/18722 0.860891503516652 0.872505198069856 HMGB1/GMNN 2 GO:0015749 monosaccharide transmembrane transport 1/320 116/18722 0.865481710014632 0.876297580441181 SLC2A3 1 GO:0030326 embryonic limb morphogenesis 1/320 116/18722 0.865481710014632 0.876297580441181 CTNNB1 1 GO:0035113 embryonic appendage morphogenesis 1/320 116/18722 0.865481710014632 0.876297580441181 CTNNB1 1 GO:0035967 cellular response to topologically incorrect protein 1/320 116/18722 0.865481710014632 0.876297580441181 HSPA1A 1 GO:0048562 embryonic organ morphogenesis 3/320 285/18722 0.86830093036412 0.878936659545454 FBN1/TGFBR1/CTNNB1 3 GO:0007613 memory 1/320 118/18722 0.870069135816835 0.880295217726533 CEBPB 1 GO:0034219 carbohydrate transmembrane transport 1/320 118/18722 0.870069135816835 0.880295217726533 SLC2A3 1 GO:0032259 methylation 4/320 364/18722 0.872196293817095 0.882231355214745 MBD3/PARP1/EZH2/CTNNB1 4 GO:0002455 humoral immune response mediated by circulating immunoglobulin 1/320 121/18722 0.876659488103046 0.886528880284333 PTPRC 1 GO:0007368 determination of left/right symmetry 1/320 124/18722 0.882916556176846 0.892637927605268 GALNT11 1 GO:0060294 cilium movement involved in cell motility 1/320 125/18722 0.884931111614174 0.894340521097976 CCSAP 1 GO:0007601 visual perception 2/320 215/18722 0.885033492441826 0.894340521097976 TIMP3/PPT1 2 GO:0031929 TOR signaling 1/320 126/18722 0.886911110769062 0.896018755427326 PDCD6 1 GO:0008033 tRNA processing 1/320 127/18722 0.888857144569551 0.897545875210505 SSB 1 GO:0048565 digestive tract development 1/320 127/18722 0.888857144569551 0.897545875210505 CTNNB1 1 GO:0050953 sensory perception of light stimulus 2/320 219/18722 0.891184988958942 0.89967661235728 TIMP3/PPT1 2 GO:0006956 complement activation 1/320 130/18722 0.894497213040819 0.902359004952311 FCN1 1 GO:0030534 adult behavior 1/320 130/18722 0.894497213040819 0.902359004952311 PPT1 1 GO:0051028 mRNA transport 1/320 130/18722 0.894497213040819 0.902359004952311 ZFP36 1 GO:0006650 glycerophospholipid metabolic process 3/320 306/18722 0.897394341365867 0.905060634250369 PLEK/DBI/ABHD8 3 GO:0032147 activation of protein kinase activity 1/320 134/18722 0.901575916225828 0.909056048278458 HMGB1 1 GO:0050684 regulation of mRNA processing 1/320 137/18722 0.906572404856197 0.91387098728124 TRA2B 1 GO:0001539 cilium or flagellum-dependent cell motility 1/320 138/18722 0.908181058633222 0.915046119061808 CCSAP 1 GO:0060285 cilium-dependent cell motility 1/320 138/18722 0.908181058633222 0.915046119061808 CCSAP 1 GO:0016579 protein deubiquitination 1/320 139/18722 0.90976209937996 0.91641564959483 CDK1 1 GO:0046395 carboxylic acid catabolic process 2/320 236/18722 0.914072503068977 0.920533166629543 CROT/SLC27A2 2 GO:0046467 membrane lipid biosynthetic process 1/320 142/18722 0.914344228526453 0.920582444510552 PLPP3 1 GO:0016054 organic acid catabolic process 2/320 240/18722 0.918760760514474 0.924803766734667 CROT/SLC27A2 2 GO:0044272 sulfur compound biosynthetic process 1/320 148/18722 0.922824248590649 0.928667753330872 PPT1 1 GO:0031497 chromatin assembly 1/320 151/18722 0.926744969793581 0.932386222348936 HMGB1 1 GO:0051168 nuclear export 1/320 154/18722 0.930467099351098 0.935903129142828 SSB 1 GO:0070646 protein modification by small protein removal 1/320 157/18722 0.934000666355963 0.939000183304827 CDK1 1 GO:1902600 proton transmembrane transport 1/320 157/18722 0.934000666355963 0.939000183304827 TMSB4X 1 GO:0006338 chromatin remodeling 2/320 255/18722 0.934286966120312 0.93905953393557 MBD3/ACTB 2 GO:0046488 phosphatidylinositol metabolic process 1/320 159/18722 0.936256343997345 0.94081011998955 PLEK 1 GO:0050806 positive regulation of synaptic transmission 1/320 164/18722 0.941564961903689 0.945914520443969 TYROBP 1 GO:0050804 modulation of chemical synaptic transmission 4/320 439/18722 0.944504934852832 0.948637430921707 TYROBP/SRGN/ITGB1/PTPRA 4 GO:0099177 regulation of trans-synaptic signaling 4/320 440/18722 0.94514625681303 0.949050870753691 TYROBP/SRGN/ITGB1/PTPRA 4 GO:0000070 mitotic sister chromatid segregation 1/320 168/18722 0.945492654620608 0.949168039089492 NEK6 1 GO:0003341 cilium movement 1/320 175/18722 0.951743347698945 0.955210957661414 CCSAP 1 GO:0006333 chromatin assembly or disassembly 1/320 177/18722 0.953394215522916 0.956635478033193 HMGB1 1 GO:0006399 tRNA metabolic process 1/320 179/18722 0.954988777350058 0.957770298060786 SSB 1 GO:0007416 synapse assembly 1/320 179/18722 0.954988777350058 0.957770298060786 RAB17 1 GO:0048839 inner ear development 1/320 188/18722 0.961517357064155 0.964083892110917 LGR5 1 GO:1901605 alpha-amino acid metabolic process 1/320 195/18722 0.965934916429781 0.968278281098461 AZIN1 1 GO:0048167 regulation of synaptic plasticity 1/320 198/18722 0.967669822074805 0.969782125833882 TYROBP 1 GO:0046474 glycerophospholipid biosynthetic process 1/320 211/18722 0.974225357944601 0.97611522284847 ABHD8 1 GO:0043583 ear development 1/320 213/18722 0.975108812509701 0.976763542615778 LGR5 1 GO:0008380 RNA splicing 3/320 434/18722 0.980196141795248 0.981621536087728 FUS/TRA2B/HSPA1A 3 GO:0016197 endosomal transport 1/320 230/18722 0.981497552130058 0.982686669590841 RAB17 1 GO:0045017 glycerolipid biosynthetic process 1/320 252/18722 0.987400650175318 0.988357433751069 ABHD8 1 GO:0006520 cellular amino acid metabolic process 1/320 284/18722 0.992801305210437 0.993522643044206 AZIN1 1 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 1/320 320/18722 0.996169430563306 0.996410575426671 TRA2B 1 GO:0000398 mRNA splicing, via spliceosome 1/320 320/18722 0.996169430563306 0.996410575426671 TRA2B 1 GO:0000375 RNA splicing, via transesterification reactions 1/320 324/18722 0.996429026830916 0.996429026830916 TRA2B 1