ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	geneName	Count
hsa03010	Ribosome	82/914	91/5868	4.96740963603373e-57	1.00341674647881e-54	6227/6232/6235/6170/6234/6168/6141/6222/25873/6228/6201/6169/6208/6210/6167/6171/6223/6164/6155/6209/6136/2197/6229/6156/6233/4736/6135/6125/6146/6202/6161/6134/6157/9349/6188/3921/6165/6158/6193/6176/6154/6187/6138/6217/6218/6203/51187/6122/6191/6130/6181/6206/6137/6204/6192/11224/6133/6230/51121/6143/6194/6147/6207/6175/6231/6159/6166/6205/6142/6129/6144/6128/6152/6160/6189/9045/200916/23521/6132/51065/6224/6173	RPS21/RPS27/RPS29/RPL39/RPS28/RPL37A/RPL18/RPS18/RPL36/RPS23/RPS7/RPL38/RPS14/RPS15A/RPL37/RPL41/RPS19/RPL34/RPL27/RPS15/RPL12/FAU/RPS24/RPL30/RPS27A/RPL10A/RPL11/RPL5/RPL22/RPS8/RPL32/RPL10/RPL27A/RPL23/RPS3/RPSA/RPL35A/RPL28/RPS5/RPLP1/RPL26/RPS2/RPL15/RPS16/RPS17/RPS9/RSL24D1/RPL3/RPS4X/RPL7A/RPLP2/RPS12/RPL13/RPS10/RPS4Y1/RPL35/RPL9/RPS25/RPL26L1/RPL19/RPS6/RPL23A/RPS13/RPLP0/RPS26/RPL29/RPL36AL/RPS11/RPL18A/RPL7/RPL21/RPL6/RPL24/RPL31/RPS3A/RPL14/RPL22L1/RPL13A/RPL8/RPS27L/RPS20/RPL36A	82
hsa05016	Huntington's disease	66/914	183/5868	4.02930524785367e-12	4.06959830033221e-10	64764/548644/4715/291/7019/4706/4705/4713/7052/1211/4708/1213/1337/4726/4716/5441/2776/55967/4729/1345/4718/374291/1329/292/29796/4710/1347/7386/6667/4728/4697/23186/7384/4694/4707/6647/1327/4698/4696/126328/5433/7417/4717/7416/5430/7381/10540/4695/5978/5435/4725/1350/9377/293/5468/51079/1351/4722/4714/54539/54205/7388/1175/27089/1173/1537	CREB3L2/POLR2J3/NDUFB9/SLC25A4/TFAM/NDUFAB1/NDUFA10/NDUFB7/TGM2/CLTA/NDUFB2/CLTC/COX6A1/NDUFS6/NDUFB10/POLR2L/GNAQ/NDUFA12/NDUFV2/COX6C/NDUFC2/NDUFS7/COX5B/SLC25A5/UQCR10/NDUFB4/COX7A2/UQCRFS1/SP1/NDUFS8/NDUFA4/RCOR1/UQCRC1/NDUFA1/NDUFB1/SOD1/COX4I1/NDUFA5/NDUFA3/NDUFA11/POLR2D/VDAC2/NDUFC1/VDAC1/POLR2A/UQCRB/DCTN2/NDUFA2/REST/POLR2F/NDUFS5/COX7C/COX5A/SLC25A6/PPARG/NDUFA13/COX8A/NDUFS3/NDUFB8/NDUFB11/CYCS/UQCRH/AP2S1/UQCRQ/AP2M1/CYC1	66
hsa03040	Spliceosome	51/914	127/5868	1.24682987668748e-11	8.39532116969573e-10	6430/4670/1655/51690/6432/8683/24148/3312/51503/6427/11017/6434/10450/84950/220988/10286/51639/10992/6637/51691/23350/57819/6631/51362/10772/3192/6629/58517/6634/25804/10594/10907/27258/55119/5093/23451/11325/6635/3178/9939/9984/6633/6628/10465/56259/27316/9128/57187/6625/84991/9879	SRSF5/HNRNPM/DDX5/LSM7/SRSF7/SRSF9/PRPF6/HSPA8/CWC15/SRSF2/SNRNP27/TRA2B/PPIE/PRPF38A/HNRNPA3/BCAS2/SF3B6/SF3B2/SNRPG/LSM8/U2SURP/LSM2/SNRPC/CDC40/SRSF10/HNRNPU/SNRPB2/RBM25/SNRPD3/LSM4/PRPF8/TXNL4A/LSM3/PRPF38B/PCBP1/SF3B1/DDX42/SNRPE/HNRNPA1/RBM8A/THOC1/SNRPD2/SNRPB/PPIH/CTNNBL1/RBMX/PRPF4/THOC2/SNRNP70/RBM17/DDX46	51
hsa05012	Parkinson's disease	50/914	130/5868	1.2771184373506e-10	6.44944810862051e-09	4715/291/4706/4705/4713/4708/1337/4726/4716/55967/4729/1345/4718/374291/1329/292/29796/4710/1347/11315/7386/4728/4697/7384/4694/4707/1327/4698/4696/126328/7417/4717/7416/7381/4695/4725/6622/1350/9377/293/51079/1351/118424/4722/4714/54539/54205/7388/27089/1537	NDUFB9/SLC25A4/NDUFAB1/NDUFA10/NDUFB7/NDUFB2/COX6A1/NDUFS6/NDUFB10/NDUFA12/NDUFV2/COX6C/NDUFC2/NDUFS7/COX5B/SLC25A5/UQCR10/NDUFB4/COX7A2/PARK7/UQCRFS1/NDUFS8/NDUFA4/UQCRC1/NDUFA1/NDUFB1/COX4I1/NDUFA5/NDUFA3/NDUFA11/VDAC2/NDUFC1/VDAC1/UQCRB/NDUFA2/NDUFS5/SNCA/COX7C/COX5A/SLC25A6/NDUFA13/COX8A/UBE2J2/NDUFS3/NDUFB8/NDUFB11/CYCS/UQCRH/UQCRQ/CYC1	50
hsa04141	Protein processing in endoplasmic reticulum	57/914	165/5868	8.50436687126727e-10	3.43576421599198e-08	27248/6238/3998/7184/2923/5034/7991/6185/64215/3309/9601/4780/10956/10961/56605/10130/1650/8454/10970/56681/6746/811/3320/7841/6745/23193/3312/6748/55741/22872/55968/55757/10134/3326/10960/64374/821/5610/10952/10905/823/7415/10277/10273/23480/440275/5589/51009/9709/23640/118424/8720/23471/5887/51726/3337/6184	ERLEC1/RRBP1/LMAN1/HSP90B1/PDIA3/P4HB/TUSC3/RPN2/DNAJC1/HSPA5/PDIA4/NFE2L2/OS9/ERP29/ERO1B/PDIA6/DDOST/CUL1/CKAP4/SAR1A/SSR2/CALR/HSP90AA1/MOGS/SSR1/GANAB/HSPA8/SSR4/EDEM2/SEC31A/NSFL1C/UGGT2/BCAP31/HSP90AB1/LMAN2/SIL1/CANX/EIF2AK2/SEC61B/MAN1A2/CAPN1/VCP/UBE4B/STUB1/SEC61G/EIF2AK4/PRKCSH/DERL2/HERPUD1/HSPBP1/UBE2J2/MBTPS1/TRAM1/RAD23B/DNAJB11/DNAJB1/RPN1	57
hsa05010	Alzheimer's disease	57/914	167/5868	1.43256812267119e-09	4.82297934632633e-08	351/4035/4311/23385/4715/3416/1020/4706/4705/4713/8883/4708/1337/4726/4716/2776/55967/4729/1345/4718/374291/1329/29796/4710/1347/7386/4728/4697/7384/4694/4707/1327/4698/4696/5663/823/126328/4717/7381/4695/4725/6622/1350/9377/51079/1351/3028/4722/4714/572/801/54539/54205/7388/51107/27089/1537	APP/LRP1/MME/NCSTN/NDUFB9/IDE/CDK5/NDUFAB1/NDUFA10/NDUFB7/NAE1/NDUFB2/COX6A1/NDUFS6/NDUFB10/GNAQ/NDUFA12/NDUFV2/COX6C/NDUFC2/NDUFS7/COX5B/UQCR10/NDUFB4/COX7A2/UQCRFS1/NDUFS8/NDUFA4/UQCRC1/NDUFA1/NDUFB1/COX4I1/NDUFA5/NDUFA3/PSEN1/CAPN1/NDUFA11/NDUFC1/UQCRB/NDUFA2/NDUFS5/SNCA/COX7C/COX5A/NDUFA13/COX8A/HSD17B10/NDUFS3/NDUFB8/BAD/CALM1/NDUFB11/CYCS/UQCRH/APH1A/UQCRQ/CYC1	57
hsa00190	Oxidative phosphorylation	48/914	132/5868	2.76971479629356e-09	7.99260555501856e-08	4715/4706/4705/4713/4708/1337/4726/4716/55967/4729/1345/4718/374291/1329/29796/4710/1347/7386/4728/537/4697/7384/4694/4707/1327/4698/5464/4696/126328/4717/7381/4695/4725/1350/9377/245973/51079/9550/1351/4722/4714/1355/54539/7388/27089/525/1537/8992	NDUFB9/NDUFAB1/NDUFA10/NDUFB7/NDUFB2/COX6A1/NDUFS6/NDUFB10/NDUFA12/NDUFV2/COX6C/NDUFC2/NDUFS7/COX5B/UQCR10/NDUFB4/COX7A2/UQCRFS1/NDUFS8/ATP6AP1/NDUFA4/UQCRC1/NDUFA1/NDUFB1/COX4I1/NDUFA5/PPA1/NDUFA3/NDUFA11/NDUFC1/UQCRB/NDUFA2/NDUFS5/COX7C/COX5A/ATP6V1C2/NDUFA13/ATP6V1G1/COX8A/NDUFS3/NDUFB8/COX15/NDUFB11/UQCRH/UQCRQ/ATP6V1B1/CYC1/ATP6V0E1	48
hsa03050	Proteasome	20/914	44/5868	2.41853907653217e-06	6.10681116824372e-05	5707/5702/5690/5694/5706/5705/5684/5689/5700/5685/5682/5693/5688/5713/5691/10197/51371/5692/5701/5720	PSMD1/PSMC3/PSMB2/PSMB6/PSMC6/PSMC5/PSMA3/PSMB1/PSMC1/PSMA4/PSMA1/PSMB5/PSMA7/PSMD7/PSMB3/PSME3/POMP/PSMB4/PSMC2/PSME1	20
hsa03060	Protein export	12/914	23/5868	4.83905954547741e-05	0.00108610003131826	3309/6729/28972/6727/23478/9789/83943/10952/6734/6731/23480/6730	HSPA5/SRP54/SPCS1/SRP14/SEC11A/SPCS2/IMMP2L/SEC61B/SRPRA/SRP72/SEC61G/SRP68	12
hsa03013	RNA transport	42/914	151/5868	7.28473030748345e-05	0.00147151552211166	5411/3837/8661/10250/8893/9669/26019/8666/65110/60528/3646/8761/7329/7341/7175/5903/8664/10921/1973/51808/79228/10605/10248/9818/1982/1964/6613/8892/84305/8894/1915/9939/9984/1207/57187/53371/5901/8662/138716/8665/1981/10557	PNN/KPNB1/EIF3A/SRRM1/EIF2B5/EIF5B/UPF2/EIF3G/UPF3A/ELAC2/EIF3E/PABPC4/UBE2I/SUMO1/TPR/RANBP2/EIF3D/RNPS1/EIF4A1/PHAX/THOC6/PAIP1/POP7/NUP58/EIF4G2/EIF1AX/SUMO2/EIF2B2/PYM1/EIF2S2/EEF1A1/RBM8A/THOC1/CLNS1A/THOC2/NUP54/RAN/EIF3B/RPP25L/EIF3F/EIF4G1/RPP38	42
hsa04144	Endocytosis	49/914	201/5868	0.000631802014217721	0.0107720399274878	1956/153/9765/137492/23550/3480/4233/22905/5590/8411/80223/11031/56288/2321/1211/1213/9525/92421/3312/84364/2348/27243/84612/83737/26119/858/84313/89853/10015/57132/11267/9101/93343/382/1601/51510/27183/2065/4734/4193/51028/1175/5878/84440/29082/1173/1785/11059/7879	EGFR/ADRB1/ZFYVE16/VPS37A/PSD4/IGF1R/MET/EPN2/PRKCZ/EEA1/RAB11FIP1/RAB31/PARD3/FLT1/CLTA/CLTC/VPS4B/CHMP4C/HSPA8/ARFGAP2/FOLR1/CHMP2A/PARD6B/ITCH/LDLRAP1/CAV2/VPS25/MVB12B/PDCD6IP/CHMP1B/SNF8/USP8/MVB12A/ARF6/DAB2/CHMP5/VPS4A/ERBB3/NEDD4/MDM2/VPS36/AP2S1/RAB5C/RAB11FIP4/CHMP4A/AP2M1/DNM2/WWP1/RAB7A	49
hsa05100	Bacterial invasion of epithelial cells	22/914	70/5868	0.000639923164009175	0.0107720399274878	999/4233/3688/3059/10095/9564/79658/1211/1213/8976/81873/10109/5879/858/1499/6464/1398/10092/2017/2549/71/1785	CDH1/MET/ITGB1/HCLS1/ARPC1B/BCAR1/ARHGAP10/CLTA/CLTC/WASL/ARPC5L/ARPC2/RAC1/CAV2/CTNNB1/SHC1/CRK/ARPC5/CTTN/GAB1/ACTG1/DNM2	22
hsa04142	Lysosome	32/914	121/5868	0.00131607321423775	0.0204497530212327	4669/3073/2548/1075/5641/1514/8722/5660/2799/2760/2517/1515/3074/1211/9741/1213/4126/1509/2990/138050/3920/537/23659/79158/10053/3916/2720/1174/1201/1512/130340/26985	NAGLU/HEXA/GAA/CTSC/LGMN/CTSL/CTSF/PSAP/GNS/GM2A/FUCA1/CTSV/HEXB/CLTA/LAPTM4A/CLTC/MANBA/CTSD/GUSB/HGSNAT/LAMP2/ATP6AP1/PLA2G15/GNPTAB/AP1M2/LAMP1/GLB1/AP1S1/CLN3/CTSH/AP1S3/AP3M1	32
hsa00270	Cysteine and methionine metabolism	13/914	36/5868	0.00203828082590021	0.0294094804879887	4548/23382/6611/1786/3945/1788/1036/58478/4507/55256/27430/6723/10768	MTR/AHCYL2/SMS/DNMT1/LDHB/DNMT3A/CDO1/ENOPH1/MTAP/ADI1/MAT2B/SRM/AHCYL1	13
hsa04520	Adherens junction	21/914	73/5868	0.00290297117765184	0.0390933451923781	1956/999/8826/3480/1500/4233/10458/5797/4008/56288/8976/7082/6934/5792/81/2064/5879/1499/5770/71/87	EGFR/CDH1/IQGAP1/IGF1R/CTNND1/MET/BAIAP2/PTPRM/LMO7/PARD3/WASL/TJP1/TCF7L2/PTPRF/ACTN4/ERBB2/RAC1/CTNNB1/PTPN1/ACTG1/ACTN1	21
hsa03008	Ribosome biogenesis in eukaryotes	22/914	79/5868	0.00363125310701017	0.0457909563998399	23160/55651/55226/134430/51602/55341/55272/4931/22803/9790/10813/26354/54433/92856/10436/10248/55505/55131/5901/138716/3692/10557	WDR43/NHP2/NAT10/WDR36/NOP58/LSG1/IMP3/NVL/XRN2/BMS1/UTP14A/GNL3/GAR1/IMP4/EMG1/POP7/NOP10/RBM28/RAN/RPP25L/EIF6/RPP38	22
hsa05130	Pathogenic Escherichia coli infection	17/914	56/5868	0.00385369435048158	0.0457909563998399	999/3688/3059/10095/3875/8976/4690/81873/10109/7430/7534/6093/1499/4691/10092/2017/71	CDH1/ITGB1/HCLS1/ARPC1B/KRT18/WASL/NCK1/ARPC5L/ARPC2/EZR/YWHAZ/ROCK1/CTNNB1/NCL/ARPC5/CTTN/ACTG1	17
hsa00510	N-Glycan biosynthesis	15/914	49/5868	0.00592738018659079	0.0665183776495189	7991/6185/2530/54344/1650/22845/4124/4248/7841/23193/2683/10905/199857/29880/6184	TUSC3/RPN2/FUT8/DPM3/DDOST/DOLK/MAN2A1/MGAT3/MOGS/GANAB/B4GALT1/MAN1A2/ALG14/ALG5/RPN1	15
hsa05131	Shigellosis	17/914	61/5868	0.00986049923166038	0.104832676041863	3688/3059/10095/8976/4790/81873/10109/5879/6093/1398/4792/10092/2017/5216/71/4793/1432	ITGB1/HCLS1/ARPC1B/WASL/NFKB1/ARPC5L/ARPC2/RAC1/ROCK1/CRK/NFKBIA/ARPC5/CTTN/PFN1/ACTG1/NFKBIB/MAPK14	17
hsa03018	RNA degradation	19/914	71/5868	0.0104220901258926	0.105263110271515	10950/170506/23016/51690/3313/22803/3329/8761/51691/246175/57819/2023/25804/27258/10766/51013/23019/28960/29883	BTG3/DHX36/EXOSC7/LSM7/HSPA9/XRN2/HSPD1/PABPC4/LSM8/CNOT6L/LSM2/ENO1/LSM4/LSM3/TOB2/EXOSC1/CNOT1/DCPS/CNOT7	19
hsa00531	Glycosaminoglycan degradation	7/914	19/5868	0.0196945868560937	0.189443168806235	4669/3073/2799/3074/2990/138050/2720	NAGLU/HEXA/GNS/HEXB/GUSB/HGSNAT/GLB1	7
hsa05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/914	74/5868	0.0321380278391323	0.295085528341124	3691/3696/1829/1605/3655/3685/2697/1832/1824/3688/3693/4000/6934/81/1499/3728/71/87	ITGB4/ITGB8/DSG2/DAG1/ITGA6/ITGAV/GJA1/DSP/DSC2/ITGB1/ITGB5/LMNA/TCF7L2/ACTN4/CTNNB1/JUP/ACTG1/ACTN1	18
hsa00020	Citrate cycle (TCA cycle)	9/914	30/5868	0.0341935793928706	0.300308827711299	3417/50/8802/3420/3418/4191/3421/4190/5160	IDH1/ACO2/SUCLG1/IDH3B/IDH2/MDH2/IDH3G/MDH1/PDHA1	9
hsa04260	Cardiac muscle contraction	18/914	77/5868	0.046020202816599	0.387336707039708	1337/6548/1345/7171/1329/29796/1347/7386/7384/1327/7381/1350/9377/1351/476/7388/27089/1537	COX6A1/SLC9A1/COX6C/TPM4/COX5B/UQCR10/COX7A2/UQCRFS1/UQCRC1/COX4I1/UQCRB/COX7C/COX5A/COX8A/ATP1A1/UQCRH/UQCRQ/CYC1	18
hsa04120	Ubiquitin mediated proteolysis	28/914	135/5868	0.0639005828922747	0.502941233425568	6477/51433/9886/8454/6502/10075/25847/55585/9690/7319/83737/51366/8065/8651/51529/7329/1642/10277/8697/10273/9616/26091/118424/10393/7334/4734/4193/11059	SIAH1/ANAPC5/RHOBTB1/CUL1/SKP2/HUWE1/ANAPC13/UBE2Q1/UBE3C/UBE2A/ITCH/UBR5/CUL5/SOCS1/ANAPC11/UBE2I/DDB1/UBE4B/CDC23/STUB1/RNF7/HERC4/UBE2J2/ANAPC10/UBE2N/NEDD4/MDM2/WWP1	28
hsa04110	Cell cycle	26/914	124/5868	0.0647350102428949	0.502941233425568	1021/5591/51433/4172/8454/1028/4616/6502/595/896/25847/10274/7531/1022/9126/51529/7534/7529/8697/10393/7532/5885/7029/4193/7465/9184	CDK6/PRKDC/ANAPC5/MCM3/CUL1/CDKN1C/GADD45B/SKP2/CCND1/CCND3/ANAPC13/STAG1/YWHAE/CDK7/SMC3/ANAPC11/YWHAZ/YWHAB/CDC23/ANAPC10/YWHAG/RAD21/TFDP2/MDM2/WEE1/BUB3	26
hsa05110	Vibrio cholerae infection	13/914	54/5868	0.0672255777117731	0.502946914732525	9601/7082/2778/11014/537/10945/10952/23480/245973/9550/71/525/8992	PDIA4/TJP1/GNAS/KDELR2/ATP6AP1/KDELR1/SEC61B/SEC61G/ATP6V1C2/ATP6V1G1/ACTG1/ATP6V1B1/ATP6V0E1	13
hsa04510	Focal adhesion	39/914	200/5868	0.0753321744260281	0.527137503392108	3911/3691/3725/3915/3696/1956/3912/1282/3655/3685/3480/4233/3688/394/3693/9564/2321/595/896/1284/10451/103910/81/2064/5879/858/6093/1499/6464/1398/4659/5170/2889/71/572/87/7094/5499/7408	LAMA5/ITGB4/JUN/LAMC1/ITGB8/EGFR/LAMB1/COL4A1/ITGA6/ITGAV/IGF1R/MET/ITGB1/ARHGAP5/ITGB5/BCAR1/FLT1/CCND1/CCND3/COL4A2/VAV3/MYL12B/ACTN4/ERBB2/RAC1/CAV2/ROCK1/CTNNB1/SHC1/CRK/PPP1R12A/PDPK1/RAPGEF1/ACTG1/BAD/ACTN1/TLN1/PPP1CA/VASP	39
hsa04530	Tight junction	27/914	132/5868	0.0781105610073763	0.527137503392108	6709/83700/1364/4628/23136/3059/5590/2770/5521/154810/56288/2771/7082/55870/84612/1366/103910/3845/81/1499/5583/22808/2017/1365/71/87/5516	SPTAN1/JAM3/CLDN4/MYH10/EPB41L3/HCLS1/PRKCZ/GNAI1/PPP2R2B/AMOTL1/PARD3/GNAI2/TJP1/ASH1L/PARD6B/CLDN7/MYL12B/KRAS/ACTN4/CTNNB1/PRKCH/MRAS/CTTN/CLDN3/ACTG1/ACTN1/PPP2CB	27
hsa00480	Glutathione metabolism	12/914	50/5868	0.0782877480285308	0.527137503392108	3417/4259/2950/6611/2686/2954/79017/373156/3418/51060/2941/6723	IDH1/MGST3/GSTP1/SMS/GGT7/GSTZ1/GGCT/GSTK1/IDH2/TXNDC12/GSTA4/SRM	12
hsa05120	Epithelial cell signaling in Helicobacter pylori infection	15/914	68/5868	0.0979175710248095	0.638043527322952	3725/1956/83700/4233/7082/4790/537/5879/4792/5781/245973/9550/525/1432/8992	JUN/EGFR/JAM3/MET/TJP1/NFKB1/ATP6AP1/RAC1/NFKBIA/PTPN11/ATP6V1C2/ATP6V1G1/ATP6V1B1/MAPK14/ATP6V0E1	15
hsa04330	Notch signaling pathway	11/914	47/5868	0.103358045576006	0.652447662698539	23385/23220/3516/84441/55534/3280/5663/1857/8650/51107/9541	NCSTN/DTX4/RBPJ/MAML2/MAML3/HES1/PSEN1/DVL3/NUMB/APH1A/CIR1	11
hsa00511	Other glycan degradation	5/914	17/5868	0.111696912940354	0.673657400639742	3073/2517/3074/4126/2720	HEXA/FUCA1/HEXB/MANBA/GLB1	5
hsa04810	Regulation of actin cytoskeleton	40/914	213/5868	0.1133878793156	0.673657400639742	3691/3696/1956/10788/3655/3685/8826/4628/85477/3688/2768/3693/10458/10095/9564/5962/79837/55970/8976/6548/10451/103910/81873/10109/7430/3845/81/5879/23191/6093/1398/3985/22808/10092/4659/5216/71/87/5499/1730	ITGB4/ITGB8/EGFR/IQGAP2/ITGA6/ITGAV/IQGAP1/MYH10/SCIN/ITGB1/GNA12/ITGB5/BAIAP2/ARPC1B/BCAR1/RDX/PIP4K2C/GNG12/WASL/SLC9A1/VAV3/MYL12B/ARPC5L/ARPC2/EZR/KRAS/ACTN4/RAC1/CYFIP1/ROCK1/CRK/LIMK2/MRAS/ARPC5/PPP1R12A/PFN1/ACTG1/ACTN1/PPP1CA/DIAPH2	40
hsa00071	Fatty acid degradation	10/914	43/5868	0.120928109673106	0.697927947256214	1376/128/37/501/3030/1892/1632/35/3032/10455	CPT2/ADH5/ACADVL/ALDH7A1/HADHA/ECHS1/ECI1/ACADS/HADHB/ECI2	10
hsa04670	Leukocyte transendothelial migration	23/914	116/5868	0.127269433718037	0.701637451382323	83700/1364/1500/3688/394/2770/9564/2771/1366/10451/103910/7430/81/5879/6093/1499/5781/1365/71/87/4267/7408/1432	JAM3/CLDN4/CTNND1/ITGB1/ARHGAP5/GNAI1/BCAR1/GNAI2/CLDN7/VAV3/MYL12B/EZR/ACTN4/RAC1/ROCK1/CTNNB1/PTPN11/CLDN3/ACTG1/ACTN1/CD99/VASP/MAPK14	23
hsa03450	Non-homologous end-joining	4/914	13/5868	0.130997899768219	0.701637451382323	5591/7520/10111/2547	PRKDC/XRCC5/RAD50/XRCC6	4
hsa00630	Glyoxylate and dicarboxylate metabolism	5/914	18/5868	0.135831835837589	0.701637451382323	50/283871/4191/9380/4190	ACO2/PGP/MDH2/GRHPR/MDH1	5
hsa04962	Vasopressin-regulated water reabsorption	10/914	44/5868	0.135892535278423	0.701637451382323	64764/1778/1783/2778/84516/1781/140735/10540/6844/5878	CREB3L2/DYNC1H1/DYNC1LI2/GNAS/DCTN5/DYNC1I2/DYNLL2/DCTN2/VAMP2/RAB5C	10
hsa03015	mRNA surveillance pathway	17/914	83/5868	0.138938109184618	0.701637451382323	5411/8731/79869/5521/124540/10250/8106/26019/65110/10978/8761/11051/10921/10767/84305/9939/5516	PNN/RNMT/CPSF7/PPP2R2B/MSI2/SRRM1/PABPN1/UPF2/UPF3A/CLP1/PABPC4/NUDT21/RNPS1/HBS1L/PYM1/RBM8A/PPP2CB	17
hsa05216	Thyroid cancer	7/914	29/5868	0.153612999131761	0.756825020112579	999/595/6934/3845/1499/7175/5468	CDH1/CCND1/TCF7L2/KRAS/CTNNB1/TPR/PPARG	7
hsa00620	Pyruvate metabolism	9/914	40/5868	0.159355246265453	0.766214703841439	84532/31/501/3945/231/4191/9380/4190/5160	ACSS1/ACACA/ALDH7A1/LDHB/AKR1B1/MDH2/GRHPR/MDH1/PDHA1	9
hsa04115	p53 signaling pathway	14/914	68/5868	0.163105110223673	0.766214703841439	1021/6477/64065/4616/901/595/896/64393/51246/5366/900/4194/54205/4193	CDK6/SIAH1/PERP/GADD45B/CCNG2/CCND1/CCND3/ZMAT3/SHISA5/PMAIP1/CCNG1/MDM4/CYCS/MDM2	14
hsa05215	Prostate cancer	17/914	89/5868	0.214716651161146	0.98574462578526	1956/7184/64764/3480/2950/3320/595/6934/4790/3326/3845/2064/1499/4792/5170/572/4193	EGFR/HSP90B1/CREB3L2/IGF1R/GSTP1/HSP90AA1/CCND1/TCF7L2/NFKB1/HSP90AB1/KRAS/ERBB2/CTNNB1/NFKBIA/PDPK1/BAD/MDM2	17
hsa00640	Propanoate metabolism	7/914	32/5868	0.221620158901438	0.994828268846454	84532/31/501/3030/3945/1892/8802	ACSS1/ACACA/ALDH7A1/HADHA/LDHB/ECHS1/SUCLG1	7
hsa00052	Galactose metabolism	6/914	27/5868	0.235483691833046	1	2548/231/2683/2720/7360/5211	GAA/AKR1B1/B4GALT1/GLB1/UGP2/PFKL	6
hsa00280	Valine, leucine and isoleucine degradation	9/914	44/5868	0.238165585161264	1	501/3030/1892/587/35/3032/11112/3028/3712	ALDH7A1/HADHA/ECHS1/BCAT2/ACADS/HADHB/HIBADH/HSD17B10/IVD	9
hsa00290	Valine, leucine and isoleucine biosynthesis	3/914	11/5868	0.238741216637229	1	55699/587/5160	IARS2/BCAT2/PDHA1	3
hsa03410	Base excision repair	7/914	33/5868	0.246345017630539	1	4350/142/27301/6996/7515/3146/5425	MPG/PARP1/APEX2/TDG/XRCC1/HMGB1/POLD2	7
hsa00410	beta-Alanine metabolism	5/914	22/5868	0.250560590848554	1	501/6611/3030/1892/6723	ALDH7A1/SMS/HADHA/ECHS1/SRM	5
hsa04145	Phagosome	27/914	153/5868	0.268157305232896	1	3685/81035/1778/3688/1514/3693/8411/4973/1783/811/3920/537/9554/5879/821/10952/3916/1781/23480/245973/9550/71/5878/525/8992/8417/7879	ITGAV/COLEC12/DYNC1H1/ITGB1/CTSL/ITGB5/EEA1/OLR1/DYNC1LI2/CALR/LAMP2/ATP6AP1/SEC22B/RAC1/CANX/SEC61B/LAMP1/DYNC1I2/SEC61G/ATP6V1C2/ATP6V1G1/ACTG1/RAB5C/ATP6V1B1/ATP6V0E1/STX7/RAB7A	27
hsa03020	RNA polymerase	6/914	29/5868	0.291939835448286	1	548644/5441/5433/5430/5435/51728	POLR2J3/POLR2L/POLR2D/POLR2A/POLR2F/POLR3K	6
hsa04130	SNARE interactions in vesicular transport	7/914	36/5868	0.3247159680796	1	9527/8673/9554/8675/10791/6844/8417	GOSR1/VAMP8/SEC22B/STX16/VAMP5/VAMP2/STX7	7
hsa05222	Small cell lung cancer	15/914	85/5868	0.34156056288166	1	3911/3915/3912/1282/3655/1021/3685/3688/9618/6502/595/4790/1284/4792/54205	LAMA5/LAMC1/LAMB1/COL4A1/ITGA6/CDK6/ITGAV/ITGB1/TRAF4/SKP2/CCND1/NFKB1/COL4A2/NFKBIA/CYCS	15
hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	5/914	26/5868	0.381231328165121	1	2135/26035/26229/90161/2132	EXTL2/GLCE/B3GAT3/HS6ST2/EXT2	5
hsa00030	Pentose phosphate pathway	5/914	27/5868	0.414355790967865	1	7086/226/25796/22934/5211	TKT/ALDOA/PGLS/RPIA/PFKL	5
hsa04722	Neurotrophin signaling pathway	21/914	127/5868	0.419180107572252	1	3725/9500/4790/7531/3845/5879/7534/6464/1398/7529/5663/4792/818/5781/2549/7532/2889/572/801/4793/1432	JUN/MAGED1/NFKB1/YWHAE/KRAS/RAC1/YWHAZ/SHC1/CRK/YWHAB/PSEN1/NFKBIA/CAMK2G/PTPN11/GAB1/YWHAG/RAPGEF1/BAD/CALM1/NFKBIB/MAPK14	21
hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	3/914	15/5868	0.420933869292199	1	2530/8702/2683	FUT8/B4GALT4/B4GALT1	3
hsa00604	Glycosphingolipid biosynthesis - ganglio series	3/914	15/5868	0.420933869292199	1	3073/3074/2720	HEXA/HEXB/GLB1	3
hsa00900	Terpenoid backbone biosynthesis	3/914	15/5868	0.420933869292199	1	10654/2224/3422	PMVK/FDPS/IDI1	3
hsa05213	Endometrial cancer	9/914	52/5868	0.422200341812958	1	1956/999/595/6934/3845/2064/1499/5170/572	EGFR/CDH1/CCND1/TCF7L2/KRAS/ERBB2/CTNNB1/PDPK1/BAD	9
hsa00010	Glycolysis / Gluconeogenesis	11/914	65/5868	0.433574400363064	1	84532/128/501/3945/2023/10327/669/226/5160/7167/5211	ACSS1/ADH5/ALDH7A1/LDHB/ENO1/AKR1A1/BPGM/ALDOA/PDHA1/TPI1/PFKL	11
hsa04360	Axon guidance	21/914	129/5868	0.449620986122935	1	2050/5921/4233/1942/57556/3688/80031/6405/2770/10725/1020/4775/1808/2771/8829/4690/3845/57522/5879/6093/3985	EPHB4/RASA1/MET/EFNA1/SEMA6A/ITGB1/SEMA6D/SEMA3F/GNAI1/NFAT5/CDK5/NFATC3/DPYSL2/GNAI2/NRP1/NCK1/KRAS/SRGAP1/RAC1/ROCK1/LIMK2	21
hsa00350	Tyrosine metabolism	7/914	41/5868	0.46066564397931	1	60487/128/1312/2954/51409/4282/55798	TRMT11/ADH5/COMT/GSTZ1/HEMK1/MIF/METTL2B	7
hsa04146	Peroxisome	13/914	79/5868	0.461805659903004	1	3417/11001/2053/25824/1891/10654/5052/6647/373156/3418/5264/10455/4358	IDH1/SLC27A2/EPHX2/PRDX5/ECH1/PMVK/PRDX1/SOD1/GSTK1/IDH2/PHYH/ECI2/MPV17	13
hsa00770	Pantothenate and CoA biosynthesis	3/914	16/5868	0.464911608953538	1	587/80025/79717	BCAT2/PANK2/PPCS	3
hsa00330	Arginine and proline metabolism	9/914	54/5868	0.46950674949982	1	501/6611/1159/5832/445/6303/548596/6723/2746	ALDH7A1/SMS/CKMT1B/ALDH18A1/ASS1/SAT1/CKMT1A/SRM/GLUD1	9
hsa00430	Taurine and hypotaurine metabolism	2/914	10/5868	0.476840234813195	1	2686/1036	GGT7/CDO1	2
hsa00520	Amino sugar and nucleotide sugar metabolism	8/914	48/5868	0.477960055466105	1	3073/3074/5238/55577/5373/51706/2673/7360	HEXA/HEXB/PGM3/NAGK/PMM2/CYB5R1/GFPT1/UGP2	8
hsa04662	B cell receptor signaling pathway	12/914	75/5868	0.508796052453935	1	3725/975/10725/2353/4775/4790/10451/29760/3845/5879/4792/4793	JUN/CD81/NFAT5/FOS/NFATC3/NFKB1/VAV3/BLNK/KRAS/RAC1/NFKBIA/NFKBIB	12
hsa00512	Mucin type O-Glycan biosynthesis	5/914	30/5868	0.511211115903099	1	63917/374378/29071/56913/2589	GALNT11/GALNT18/C1GALT1C1/C1GALT1/GALNT1	5
hsa04977	Vitamin digestion and absorption	4/914	24/5868	0.527066758148709	1	6573/80704/113278/686	SLC19A1/SLC19A3/SLC52A3/BTD	4
hsa04612	Antigen processing and presentation	12/914	76/5868	0.528574135095543	1	2923/3309/5641/1514/811/3320/3312/3326/821/10197/8625/5720	PDIA3/HSPA5/LGMN/CTSL/CALR/HSP90AA1/HSPA8/HSP90AB1/CANX/PSME3/RFXANK/PSME1	12
hsa04621	NOD-like receptor signaling pathway	9/914	58/5868	0.561085811768887	1	7184/10454/3320/4790/7205/3326/4792/4793/1432	HSP90B1/TAB1/HSP90AA1/NFKB1/TRIP6/HSP90AB1/NFKBIA/NFKBIB/MAPK14	9
hsa04512	ECM-receptor interaction	13/914	85/5868	0.575393213812911	1	3911/3691/3915/3696/3912/1282/1605/3655/3685/3688/3693/961/1284	LAMA5/ITGB4/LAMC1/ITGB8/LAMB1/COL4A1/DAG1/ITGA6/ITGAV/ITGB1/ITGB5/CD47/COL4A2	13
hsa00100	Steroid biosynthesis	3/914	19/5868	0.586521536148483	1	1718/6713/6307	DHCR24/SQLE/MSMO1	3
hsa04114	Oocyte meiosis	17/914	112/5868	0.587378686943321	1	3480/51433/8454/9748/25847/7531/9126/51529/7534/7529/8697/818/10393/7532/801/5516/5499	IGF1R/ANAPC5/CUL1/SLK/ANAPC13/YWHAE/SMC3/ANAPC11/YWHAZ/YWHAB/CDC23/CAMK2G/ANAPC10/YWHAG/CALM1/PPP2CB/PPP1CA	17
hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	4/914	26/5868	0.593883099257024	1	10331/8702/2683/10402	B3GNT3/B4GALT4/B4GALT1/ST3GAL6	4
hsa04666	Fc gamma R-mediated phagocytosis	14/914	94/5868	0.617148624944797	1	8613/85477/10095/8976/10451/81873/10109/5879/1398/3985/10092/382/7408/1785	PLPP3/SCIN/ARPC1B/WASL/VAV3/ARPC5L/ARPC2/RAC1/CRK/LIMK2/ARPC5/ARF6/VASP/DNM2	14
hsa04966	Collecting duct acid secretion	4/914	27/5868	0.625105239829051	1	245973/9550/525/8992	ATP6V1C2/ATP6V1G1/ATP6V1B1/ATP6V0E1	4
hsa05210	Colorectal cancer	9/914	62/5868	0.645385972546054	1	3725/2353/595/6934/3845/5879/1499/572/54205	JUN/FOS/CCND1/TCF7L2/KRAS/RAC1/CTNNB1/BAD/CYCS	9
hsa05143	African trypanosomiasis	5/914	35/5868	0.655103385505027	1	3039/3040/8542/2776/3043	HBA1/HBA2/APOL1/GNAQ/HBB	5
hsa05219	Bladder cancer	6/914	42/5868	0.65676726655114	1	1956/999/595/3845/2064/4193	EGFR/CDH1/CCND1/KRAS/ERBB2/MDM2	6
hsa00603	Glycosphingolipid biosynthesis - globo series	2/914	14/5868	0.665540757676089	1	3073/3074	HEXA/HEXB	2
hsa05211	Renal cell carcinoma	10/914	70/5868	0.668167025055452	1	3725/4233/2034/3845/5879/1398/5781/2549/2889/6513	JUN/MET/EPAS1/KRAS/RAC1/CRK/PTPN11/GAB1/RAPGEF1/SLC2A1	10
hsa05142	Chagas disease (American trypanosomiasis)	15/914	104/5868	0.669686164381677	1	3725/8837/2770/2353/5521/811/2771/2776/2778/4790/2767/4792/3459/5516/1432	JUN/CFLAR/GNAI1/FOS/PPP2R2B/CALR/GNAI2/GNAQ/GNAS/NFKB1/GNA11/NFKBIA/IFNGR1/PPP2CB/MAPK14	15
hsa00051	Fructose and mannose metabolism	5/914	36/5868	0.680386826956901	1	231/5373/226/7167/5211	AKR1B1/PMM2/ALDOA/TPI1/PFKL	5
hsa03030	DNA replication	5/914	36/5868	0.680386826956901	1	4172/6742/246243/5558/5425	MCM3/SSBP1/RNASEH1/PRIM2/POLD2	5
hsa00340	Histidine metabolism	4/914	29/5868	0.682793792292055	1	60487/501/51409/55798	TRMT11/ALDH7A1/HEMK1/METTL2B	4
hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	3/914	22/5868	0.688899872814957	1	79586/26229/113189	CHPF/B3GAT3/CHST14	3
hsa04710	Circadian rhythm	3/914	22/5868	0.688899872814957	1	79365/8454/1453	BHLHE41/CUL1/CSNK1D	3
hsa05146	Amoebiasis	15/914	106/5868	0.699040048022127	1	3911/3915/3912/1282/2776/2778/4790/1284/81/2767/1992/87/5878/3315/7879	LAMA5/LAMC1/LAMB1/COL4A1/GNAQ/GNAS/NFKB1/COL4A2/ACTN4/GNA11/SERPINB1/ACTN1/RAB5C/HSPB1/RAB7A	15
hsa00310	Lysine degradation	6/914	44/5868	0.702082710630225	1	501/3030/1892/55870/64324/79813	ALDH7A1/HADHA/ECHS1/ASH1L/NSD1/EHMT1	6
hsa05214	Glioma	9/914	65/5868	0.702225825617171	1	1956/1021/3480/595/3845/6464/818/801/4193	EGFR/CDK6/IGF1R/CCND1/KRAS/SHC1/CAMK2G/CALM1/MDM2	9
hsa04914	Progesterone-mediated oocyte maturation	12/914	86/5868	0.706863317773348	1	3480/51433/2770/3320/2771/25847/3326/3845/51529/8697/10393/1432	IGF1R/ANAPC5/GNAI1/HSP90AA1/GNAI2/ANAPC13/HSP90AB1/KRAS/ANAPC11/CDC23/ANAPC10/MAPK14	12
hsa00650	Butanoate metabolism	4/914	30/5868	0.709191127121125	1	3030/1892/35/5160	HADHA/ECHS1/ACADS/PDHA1	4
hsa04964	Proximal tubule bicarbonate reclamation	3/914	23/5868	0.718476031169806	1	4190/476/2746	MDH1/ATP1A1/GLUD1	3
hsa05220	Chronic myeloid leukemia	10/914	73/5868	0.720223541790628	1	1021/595/4790/3845/6464/1398/4792/5781/572/4193	CDK6/CCND1/NFKB1/KRAS/SHC1/CRK/NFKBIA/PTPN11/BAD/MDM2	10
hsa00564	Glycerophospholipid metabolism	11/914	80/5868	0.72104543512554	1	8613/57678/23171/8527/10162/1040/23761/23659/10434/11313/8760	PLPP3/GPAM/GPD1L/DGKD/LPCAT3/CDS1/PISD/PLA2G15/LYPLA1/LYPLA2/CDS2	11
hsa04310	Wnt signaling pathway	21/914	150/5868	0.738480091108721	1	3725/6477/4041/8454/10725/4775/595/896/6934/6907/8323/5879/6093/1499/5663/56998/818/1857/23401/5516/1452	JUN/SIAH1/LRP5/CUL1/NFAT5/NFATC3/CCND1/CCND3/TCF7L2/TBL1X/FZD6/RAC1/ROCK1/CTNNB1/PSEN1/CTNNBIP1/CAMK2G/DVL3/FRAT2/PPP2CB/CSNK1A1	21
hsa00760	Nicotinate and nicotinamide metabolism	3/914	24/5868	0.745820213029963	1	23475/54981/30833	QPRT/NMRK1/NT5C	3
hsa04320	Dorso-ventral axis formation	3/914	24/5868	0.745820213029963	1	1956/3845/2114	EGFR/KRAS/ETS2	3
hsa00040	Pentose and glucuronate interconversions	4/914	32/5868	0.757087346637821	1	2990/231/51181/7360	GUSB/AKR1B1/DCXR/UGP2	4
hsa00250	Alanine, aspartate and glutamate metabolism	4/914	32/5868	0.757087346637821	1	445/2673/5471/2746	ASS1/GFPT1/PPAT/GLUD1	4
hsa00260	Glycine, serine and threonine metabolism	4/914	32/5868	0.757087346637821	1	2731/501/212/211	GLDC/ALDH7A1/ALAS2/ALAS1	4
hsa05223	Non-small cell lung cancer	7/914	54/5868	0.757729509716162	1	1956/1021/595/3845/2064/5170/572	EGFR/CDK6/CCND1/KRAS/ERBB2/PDPK1/BAD	7
hsa04540	Gap junction	12/914	90/5868	0.76499885088125	1	1956/153/2697/2770/2771/2776/7082/2778/3845/10746/2767/1453	EGFR/ADRB1/GJA1/GNAI1/GNAI2/GNAQ/TJP1/GNAS/KRAS/MAP3K2/GNA11/CSNK1D	12
hsa05414	Dilated cardiomyopathy	12/914	90/5868	0.76499885088125	1	3691/3696/153/1605/3655/3685/3688/3693/4000/2778/7171/71	ITGB4/ITGB8/ADRB1/DAG1/ITGA6/ITGAV/ITGB1/ITGB5/LMNA/GNAS/TPM4/ACTG1	12
hsa05145	Toxoplasmosis	18/914	132/5868	0.767554240694001	1	3911/3915/3912/3655/3688/10454/3588/2770/3312/2771/4790/8651/4792/572/3459/4793/54205/1432	LAMA5/LAMC1/LAMB1/ITGA6/ITGB1/TAB1/IL10RB/GNAI1/HSPA8/GNAI2/NFKB1/SOCS1/NFKBIA/BAD/IFNGR1/NFKBIB/CYCS/MAPK14	18
hsa00450	Selenocompound metabolism	2/914	17/5868	0.767858158218126	1	4548/10587	MTR/TXNRD2	2
hsa04614	Renin-angiotensin system	2/914	17/5868	0.767858158218126	1	2028/4311	ENPEP/MME	2
hsa04730	Long-term depression	9/914	70/5868	0.783210941461868	1	3480/2768/2770/2771/2776/2778/3845/2767/5516	IGF1R/GNA12/GNAI1/GNAI2/GNAQ/GNAS/KRAS/GNA11/PPP2CB	9
hsa05416	Viral myocarditis	9/914	70/5868	0.783210941461868	1	1605/4628/595/1604/5879/1982/71/54205/1981	DAG1/MYH10/CCND1/CD55/RAC1/EIF4G2/ACTG1/CYCS/EIF4G1	9
hsa05160	Hepatitis C	18/914	134/5868	0.789198018346957	1	1956/1364/975/5521/7098/4790/1366/3646/3845/5610/4792/10197/440275/1365/572/5516/3454/1432	EGFR/CLDN4/CD81/PPP2R2B/TLR3/NFKB1/CLDN7/EIF3E/KRAS/EIF2AK2/NFKBIA/PSME3/EIF2AK4/CLDN3/BAD/PPP2CB/IFNAR1/MAPK14	18
hsa00240	Pyrimidine metabolism	13/914	99/5868	0.789860165215355	1	548644/5441/10587/5433/30833/5430/50808/5558/5435/7372/5425/51727/51728	POLR2J3/POLR2L/TXNRD2/POLR2D/NT5C/POLR2A/AK3/PRIM2/POLR2F/UMPS/POLD2/CMPK1/POLR3K	13
hsa00670	One carbon pool by folate	2/914	18/5868	0.795346218932974	1	4548/471	MTR/ATIC	2
hsa05218	Melanoma	9/914	71/5868	0.797304202060042	1	1956/999/1021/3480/4233/595/3845/572/4193	EGFR/CDH1/CDK6/IGF1R/MET/CCND1/KRAS/BAD/MDM2	9
hsa05221	Acute myeloid leukemia	7/914	57/5868	0.806080966772033	1	1050/595/6934/4790/3845/3728/572	CEBPA/CCND1/TCF7L2/NFKB1/KRAS/JUP/BAD	7
hsa05140	Leishmaniasis	9/914	72/5868	0.810707523400541	1	3725/3688/10454/2353/4790/4792/3459/4793/1432	JUN/ITGB1/TAB1/FOS/NFKB1/NFKBIA/IFNGR1/NFKBIB/MAPK14	9
hsa00561	Glycerolipid metabolism	6/914	50/5868	0.812772663673477	1	8613/501/57678/231/8527/10327	PLPP3/ALDH7A1/GPAM/AKR1B1/DGKD/AKR1A1	6
hsa04122	Sulfur relay system	1/914	10/5868	0.816327650773962	1	4338	MOCS2	1
hsa04012	ErbB signaling pathway	11/914	87/5868	0.816924755366029	1	3725/1956/4690/3845/2064/6464/1398/818/2549/572/2065	JUN/EGFR/NCK1/KRAS/ERBB2/SHC1/CRK/CAMK2G/GAB1/BAD/ERBB3	11
hsa05020	Prion diseases	4/914	35/5868	0.81716746681138	1	3915/3309/1958/6647	LAMC1/HSPA5/EGR1/SOD1	4
hsa05144	Malaria	6/914	51/5868	0.82763980979535	1	4035/4233/3039/975/3040/3043	LRP1/MET/HBA1/CD81/HBA2/HBB	6
hsa03440	Homologous recombination	3/914	28/5868	0.834483295669944	1	10111/6742/5425	RAD50/SSBP1/POLD2	3
hsa04971	Gastric acid secretion	9/914	74/5868	0.835490496379313	1	2770/6548/2771/2776/2778/7430/818/476/801	GNAI1/SLC9A1/GNAI2/GNAQ/GNAS/EZR/CAMK2G/ATP1A1/CALM1	9
hsa03420	Nucleotide excision repair	5/914	44/5868	0.837160137354167	1	1022/404672/1642/5887/5425	CDK7/GTF2H5/DDB1/RAD23B/POLD2	5
hsa00790	Folate biosynthesis	1/914	11/5868	0.844985303077239	1	5860	QDPR	1
hsa05410	Hypertrophic cardiomyopathy (HCM)	10/914	83/5868	0.853221413835673	1	3691/3696/1605/3655/3685/3688/3693/4000/7171/71	ITGB4/ITGB8/DAG1/ITGA6/ITGAV/ITGB1/ITGB5/LMNA/TPM4/ACTG1	10
hsa01040	Biosynthesis of unsaturated fatty acids	2/914	21/5868	0.86125057231899	1	3030/9524	HADHA/TECR	2
hsa04380	Osteoclast differentiation	16/914	128/5868	0.864472551744884	1	3725/10454/2353/2354/4790/2274/29760/8651/5879/3727/4792/5468/8878/3459/3454/1432	JUN/TAB1/FOS/FOSB/NFKB1/FHL2/BLNK/SOCS1/RAC1/JUND/NFKBIA/PPARG/SQSTM1/IFNGR1/IFNAR1/MAPK14	16
hsa05212	Pancreatic cancer	8/914	70/5868	0.873401587100074	1	1956/1021/595/4790/3845/2064/5879/572	EGFR/CDK6/CCND1/NFKB1/KRAS/ERBB2/RAC1/BAD	8
hsa05200	Pathways in cancer	44/914	326/5868	0.874826671203271	1	3911/3725/3915/1956/3912/1282/999/3655/1021/7184/3685/1441/3480/4233/3688/2034/1050/2353/2737/9618/2950/1438/6502/3320/595/6934/4790/1284/3326/3845/2064/8323/5879/1499/7175/1398/4792/1857/5468/3728/572/54205/4193/6513	LAMA5/JUN/LAMC1/EGFR/LAMB1/COL4A1/CDH1/ITGA6/CDK6/HSP90B1/ITGAV/CSF3R/IGF1R/MET/ITGB1/EPAS1/CEBPA/FOS/GLI3/TRAF4/GSTP1/CSF2RA/SKP2/HSP90AA1/CCND1/TCF7L2/NFKB1/COL4A2/HSP90AB1/KRAS/ERBB2/FZD6/RAC1/CTNNB1/TPR/CRK/NFKBIA/DVL3/PPARG/JUP/BAD/CYCS/MDM2/SLC2A1	44
hsa04912	GnRH signaling pathway	12/914	101/5868	0.882190099987905	1	3725/1956/4216/2776/2778/4323/3845/10746/2767/818/801/1432	JUN/EGFR/MAP3K4/GNAQ/GNAS/MMP14/KRAS/MAP3K2/GNA11/CAMK2G/CALM1/MAPK14	12
hsa04916	Melanogenesis	12/914	101/5868	0.882190099987905	1	64764/2770/2771/2776/6934/2778/3845/8323/1499/818/1857/801	CREB3L2/GNAI1/GNAI2/GNAQ/TCF7L2/GNAS/KRAS/FZD6/CTNNB1/CAMK2G/DVL3/CALM1	12
hsa00600	Sphingolipid metabolism	4/914	40/5868	0.889819713941553	1	8613/8560/2531/2720	PLPP3/DEGS1/KDSR/GLB1	4
hsa00910	Nitrogen metabolism	2/914	23/5868	0.893724652850307	1	767/2746	CA8/GLUD1	2
hsa03430	Mismatch repair	2/914	23/5868	0.893724652850307	1	6742/5425	SSBP1/POLD2	2
hsa04514	Cell adhesion molecules (CAMs)	16/914	133/5868	0.899865110790955	1	3696/999/83700/3655/1364/3685/3688/26047/5797/2734/5792/1366/9019/23705/1365/4267	ITGB8/CDH1/JAM3/ITGA6/CLDN4/ITGAV/ITGB1/CNTNAP2/PTPRM/GLG1/PTPRF/CLDN7/MPZL1/CADM1/CLDN3/CD99	16
hsa04970	Salivary secretion	10/914	89/5868	0.90528069128451	1	490/153/3783/1471/6548/2776/2778/476/801/6844	ATP2B1/ADRB1/KCNN4/CST3/SLC9A1/GNAQ/GNAS/ATP1A1/CALM1/VAMP2	10
hsa00860	Porphyrin and chlorophyll metabolism	4/914	43/5868	0.920065426108934	1	212/2990/1355/211	ALAS2/GUSB/COX15/ALAS1	4
hsa04350	TGF-beta signaling pathway	9/914	84/5868	0.923556697803606	1	9765/655/8454/3398/3397/4052/6667/6093/5516	ZFYVE16/BMP7/CUL1/ID2/ID1/LTBP1/SP1/ROCK1/PPP2CB	9
hsa04910	Insulin signaling pathway	16/914	138/5868	0.927360295216303	1	31/5590/5792/8651/3845/6464/1398/10211/6194/5170/5257/5770/2889/572/801/5499	ACACA/PRKCZ/PTPRF/SOCS1/KRAS/SHC1/CRK/FLOT1/RPS6/PDPK1/PHKB/PTPN1/RAPGEF1/BAD/CALM1/PPP1CA	16
hsa04660	T cell receptor signaling pathway	12/914	108/5868	0.928314605415122	1	3725/10725/2353/4775/4790/10451/4690/3845/4792/1739/4793/1432	JUN/NFAT5/FOS/NFATC3/NFKB1/VAV3/NCK1/KRAS/NFKBIA/DLG1/NFKBIB/MAPK14	12
hsa05014	Amyotrophic lateral sclerosis (ALS)	5/914	53/5868	0.931949006452469	1	5879/6647/572/54205/1432	RAC1/SOD1/BAD/CYCS/MAPK14	5
hsa03022	Basal transcription factors	3/914	36/5868	0.935038568801534	1	6883/6882/27097	TAF12/TAF11/TAF5L	3
hsa00360	Phenylalanine metabolism	1/914	17/5868	0.944016584551724	1	4282	MIF	1
hsa05217	Basal cell carcinoma	5/914	55/5868	0.944685558517567	1	2737/6934/8323/1499/1857	GLI3/TCF7L2/FZD6/CTNNB1/DVL3	5
hsa04974	Protein digestion and absorption	8/914	81/5868	0.950079991440933	1	7373/1282/54407/4311/3783/1284/1803/476	COL14A1/COL4A1/SLC38A2/MME/KCNN4/COL4A2/DPP4/ATP1A1	8
hsa04340	Hedgehog signaling pathway	5/914	56/5868	0.950210001713147	1	4036/655/2737/1453/1452	LRP2/BMP7/GLI3/CSNK1D/CSNK1A1	5
hsa05323	Rheumatoid arthritis	9/914	91/5868	0.95779125450849	1	3725/1514/2353/2321/537/245973/9550/525/8992	JUN/CTSL/FOS/FLT1/ATP6AP1/ATP6V1C2/ATP6V1G1/ATP6V1B1/ATP6V0E1	9
hsa04370	VEGF signaling pathway	7/914	76/5868	0.96321099528453	1	10725/4775/3845/5879/572/1432/3315	NFAT5/NFATC3/KRAS/RAC1/BAD/MAPK14/HSPB1	7
hsa00380	Tryptophan metabolism	3/914	42/5868	0.96937727937486	1	501/3030/1892	ALDH7A1/HADHA/ECHS1	3
hsa04960	Aldosterone-regulated sodium reabsorption	3/914	42/5868	0.96937727937486	1	3845/5170/476	KRAS/PDPK1/ATP1A1	3
hsa03320	PPAR signaling pathway	6/914	70/5868	0.971566541518553	1	11001/1376/4973/1622/5170/5468	SLC27A2/CPT2/OLR1/DBI/PDPK1/PPARG	6
hsa04720	Long-term potentiation	6/914	70/5868	0.971566541518553	1	2776/3845/818/4659/801/5499	GNAQ/KRAS/CAMK2G/PPP1R12A/CALM1/PPP1CA	6
hsa00980	Metabolism of xenobiotics by cytochrome P450	6/914	71/5868	0.974399815131241	1	4259/128/2950/2954/373156/2941	MGST3/ADH5/GSTP1/GSTZ1/GSTK1/GSTA4	6
hsa04622	RIG-I-like receptor signaling pathway	6/914	71/5868	0.974399815131241	1	4790/1654/4792/4793/1432/5300	NFKB1/DDX3X/NFKBIA/NFKBIB/MAPK14/PIN1	6
hsa00230	Purine metabolism	17/914	162/5868	0.977097472555113	1	548644/271/5150/5441/353/5471/132/5433/471/30833/5430/5558/5435/5425/11164/51728/1716	POLR2J3/AMPD2/PDE7A/POLR2L/APRT/PPAT/ADK/POLR2D/ATIC/NT5C/POLR2A/PRIM2/POLR2F/POLD2/NUDT5/POLR3K/DGUOK	17
hsa04140	Regulation of autophagy	2/914	34/5868	0.977282469321996	1	84938/23710	ATG4C/GABARAPL1	2
hsa00500	Starch and sucrose metabolism	4/914	54/5868	0.977408695442471	1	2548/178/2990/7360	GAA/AGL/GUSB/UGP2	4
hsa00982	Drug metabolism - cytochrome P450	6/914	73/5868	0.979299921005774	1	4259/128/2950/2954/373156/2941	MGST3/ADH5/GSTP1/GSTZ1/GSTK1/GSTA4	6
hsa05340	Primary immunodeficiency	2/914	35/5868	0.980351662899036	1	29760/8625	BLNK/RFXANK	2
hsa04623	Cytosolic DNA-sensing pathway	4/914	56/5868	0.982264847852713	1	4790/4792/4793/51728	NFKB1/NFKBIA/NFKBIB/POLR3K	4
hsa00565	Ether lipid metabolism	2/914	36/5868	0.983017139022418	1	8613/5049	PLPP3/PAFAH1B2	2
hsa04620	Toll-like receptor signaling pathway	9/914	102/5868	0.984697005421649	1	3725/10454/2353/7098/4790/5879/4792/3454/1432	JUN/TAB1/FOS/TLR3/NFKB1/RAC1/NFKBIA/IFNAR1/MAPK14	9
hsa00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	1/914	25/5868	0.985627295424432	1	51604	PIGT	1
hsa04950	Maturity onset diabetes of the young	1/914	25/5868	0.985627295424432	1	3280	HES1	1
hsa04920	Adipocytokine signaling pathway	5/914	68/5868	0.986905494054697	1	4790/4792/5781/4793/6513	NFKB1/NFKBIA/PTPN11/NFKBIB/SLC2A1	5
hsa00590	Arachidonic acid metabolism	4/914	59/5868	0.98773738656082	1	80142/9536/2053/2686	PTGES2/PTGES/EPHX2/GGT7	4
hsa00053	Ascorbate and aldarate metabolism	1/914	26/5868	0.987875567199559	1	501	ALDH7A1	1
hsa04210	Apoptosis	7/914	87/5868	0.987983157822726	1	8837/4790/9131/823/4792/572/54205	CFLAR/NFKB1/AIFM1/CAPN1/NFKBIA/BAD/CYCS	7
hsa04976	Bile secretion	5/914	71/5868	0.990792839486381	1	6548/2778/5243/476/6513	SLC9A1/GNAS/ABCB1/ATP1A1/SLC2A1	5
hsa04270	Vascular smooth muscle contraction	10/914	116/5868	0.99096140669303	1	2768/800/2776/2778/2767/6093/5583/4659/801/5499	GNA12/CALD1/GNAQ/GNAS/GNA11/ROCK1/PRKCH/PPP1R12A/CALM1/PPP1CA	10
hsa04010	MAPK signaling pathway	29/914	268/5868	0.991206786058421	1	3725/1956/5921/2768/10454/4216/1848/1852/2353/4616/11072/55970/3312/4790/3845/10746/5879/8491/4763/1398/22808/3727/5922/1847/6788/56940/1432/3315/1843	JUN/EGFR/RASA1/GNA12/TAB1/MAP3K4/DUSP6/DUSP9/FOS/GADD45B/DUSP14/GNG12/HSPA8/NFKB1/KRAS/MAP3K2/RAC1/MAP4K3/NF1/CRK/MRAS/JUND/RASA2/DUSP5/STK3/DUSP22/MAPK14/HSPB1/DUSP1	29
hsa04744	Phototransduction	1/914	29/5868	0.992723081788313	1	801	CALM1	1
hsa04020	Calcium signaling pathway	17/914	177/5868	0.992987062315209	1	490/1956/153/5025/291/2776/2778/292/2064/2767/7417/7416/818/5257/293/801/2065	ATP2B1/EGFR/ADRB1/P2RX4/SLC25A4/GNAQ/GNAS/SLC25A5/ERBB2/GNA11/VDAC2/VDAC1/CAMK2G/PHKB/SLC25A6/CALM1/ERBB3	17
hsa04630	Jak-STAT signaling pathway	14/914	155/5868	0.994422325564266	1	1441/3588/1438/595/896/10252/3977/8651/5618/3572/5781/200734/3459/3454	CSF3R/IL10RB/CSF2RA/CCND1/CCND3/SPRY1/LIFR/SOCS1/PRLR/IL6ST/PTPN11/SPRED2/IFNGR1/IFNAR1	14
hsa00140	Steroid hormone biosynthesis	3/914	56/5868	0.995282502578074	1	1312/3292/412	COMT/HSD17B1/STS	3
hsa00562	Inositol phosphate metabolism	3/914	57/5868	0.99589234739922	1	51477/79837/7167	ISYNA1/PIP4K2C/TPI1	3
hsa04070	Phosphatidylinositol signaling system	5/914	78/5868	0.996047247156326	1	79837/8527/1040/801/8760	PIP4K2C/DGKD/CDS1/CALM1/CDS2	5
hsa00514	Other types of O-glycan biosynthesis	2/914	46/5868	0.99616391178401	1	283464/2683	GXYLT1/B4GALT1	2
hsa04640	Hematopoietic cell lineage	6/914	88/5868	0.996172670623225	1	3655/4311/1441/1438/1604/100133941	ITGA6/MME/CSF3R/CSF2RA/CD55/CD24	6
hsa04930	Type II diabetes mellitus	2/914	48/5868	0.997166743340997	1	5590/8651	PRKCZ/SOCS1	2
hsa04062	Chemokine signaling pathway	17/914	189/5868	0.997494107258198	1	5590/2770/9564/56288/2787/55970/8976/2771/4790/10451/3845/5879/6093/6464/1398/4792/4793	PRKCZ/GNAI1/BCAR1/PARD3/GNG5/GNG12/WASL/GNAI2/NFKB1/VAV3/KRAS/RAC1/ROCK1/SHC1/CRK/NFKBIA/NFKBIB	17
hsa00983	Drug metabolism - other enzymes	2/914	52/5868	0.99846138444445	1	2990/7372	GUSB/UMPS	2
hsa04150	mTOR signaling pathway	2/914	52/5868	0.99846138444445	1	6194/5170	RPS6/PDPK1	2
hsa04664	Fc epsilon RI signaling pathway	4/914	79/5868	0.999095604754199	1	10451/3845/5879/1432	VAV3/KRAS/RAC1/MAPK14	4
hsa04972	Pancreatic secretion	6/914	101/5868	0.999206475945827	1	490/6548/2776/2778/5879/476	ATP2B1/SLC9A1/GNAQ/GNAS/RAC1/ATP1A1	6
hsa04610	Complement and coagulation cascades	3/914	69/5868	0.999249008351119	1	2153/4179/1604	F5/CD46/CD55	3
hsa04940	Type I diabetes mellitus	1/914	43/5868	0.999330673685644	1	3329	HSPD1	1
hsa02010	ABC transporters	1/914	44/5868	0.99943569759145	1	5243	ABCB1	1
hsa04973	Carbohydrate digestion and absorption	1/914	44/5868	0.99943569759145	1	476	ATP1A1	1
hsa04650	Natural killer cell mediated cytotoxicity	9/914	136/5868	0.999589040600163	1	10725/4775/10451/3845/5879/6464/5781/3459/3454	NFAT5/NFATC3/VAV3/KRAS/RAC1/SHC1/PTPN11/IFNGR1/IFNAR1	9
hsa04975	Fat digestion and absorption	1/914	46/5868	0.999598931760435	1	8613	PLPP3	1
hsa00830	Retinol metabolism	2/914	64/5868	0.999760848521244	1	128/8228	ADH5/PNPLA4	2
hsa04742	Taste transduction	1/914	52/5868	0.999856118859666	1	2778	GNAS	1
hsa00970	Aminoacyl-tRNA biosynthesis	1/914	63/5868	0.999978098437626	1	55699	IARS2	1
hsa05322	Systemic lupus erythematosus	5/914	136/5868	0.999998462684998	1	81/6634/6628/6741/87	ACTN4/SNRPD3/SNRPB/SSB/ACTN1	5
hsa04060	Cytokine-cytokine receptor interaction	13/914	265/5868	0.999999992639651	1	1956/1441/4233/655/3588/2321/1438/51330/3977/5618/3572/3459/3454	EGFR/CSF3R/MET/BMP7/IL10RB/FLT1/CSF2RA/TNFRSF12A/LIFR/PRLR/IL6ST/IFNGR1/IFNAR1	13
hsa04080	Neuroactive ligand-receptor interaction	8/914	272/5868	0.999999999999265	1	153/2564/5025/56288/5031/1140/5618/9294	ADRB1/GABRE/P2RX4/PARD3/P2RY6/CHRNB1/PRLR/S1PR2	8
hsa04740	Olfactory transduction	2/914	388/5868	1	1	818/801	CAMK2G/CALM1	2