ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	geneName	Count
hsa03050	Proteasome	21/556	44/5868	5.61191134749531e-11	7.19528736348338e-09	5698/5696/10213/5713/5721/5707/5690/5700/5689/5702/5694/5693/5706/5684/5704/5682/5695/5720/5708/9861/5692	PSMB9/PSMB8/PSMD14/PSMD7/PSME2/PSMD1/PSMB2/PSMC1/PSMB1/PSMC3/PSMB6/PSMB5/PSMC6/PSMA3/PSMC4/PSMA1/PSMB7/PSME1/PSMD2/PSMD6/PSMB4	21
hsa04612	Antigen processing and presentation	28/556	76/5868	7.30486026749581e-11	7.19528736348338e-09	3106/3105/3107/1514/567/1520/3326/3133/3113/3122/3320/3134/5721/5641/3309/3123/3115/10437/972/6890/811/3108/3117/5720/6892/3312/3118/3109	HLA-B/HLA-A/HLA-C/CTSL/B2M/CTSS/HSP90AB1/HLA-E/HLA-DPA1/HLA-DRA/HSP90AA1/HLA-F/PSME2/LGMN/HSPA5/HLA-DRB1/HLA-DPB1/IFI30/CD74/TAP1/CALR/HLA-DMA/HLA-DQA1/PSME1/TAPBP/HSPA8/HLA-DQA2/HLA-DMB	28
hsa05140	Leishmaniasis	25/556	72/5868	3.28108950773468e-09	2.11706501101751e-07	2214/1535/3113/3460/4688/653361/3122/4792/3688/6772/2353/3123/3115/5777/7040/65108/3716/3108/3117/7097/3725/3118/2212/3717/3109	FCGR3A/CYBA/HLA-DPA1/IFNGR2/NCF2/NCF1/HLA-DRA/NFKBIA/ITGB1/STAT1/FOS/HLA-DRB1/HLA-DPB1/PTPN6/TGFB1/MARCKSL1/JAK1/HLA-DMA/HLA-DQA1/TLR2/JUN/HLA-DQA2/FCGR2A/JAK2/HLA-DMB	25
hsa04145	Phagosome	39/556	153/5868	4.29860915942642e-09	2.11706501101751e-07	3106/3105/3107/1514/81035/2214/1520/525/7037/245973/1535/3133/3693/1536/3113/4973/10383/4688/653361/3122/3688/3134/203068/929/3123/3115/9296/10376/6890/811/3108/84790/3117/7097/60/3118/2212/529/3109	HLA-B/HLA-A/HLA-C/CTSL/COLEC12/FCGR3A/CTSS/ATP6V1B1/TFRC/ATP6V1C2/CYBA/HLA-E/ITGB5/CYBB/HLA-DPA1/OLR1/TUBB4B/NCF2/NCF1/HLA-DRA/ITGB1/HLA-F/TUBB/CD14/HLA-DRB1/HLA-DPB1/ATP6V1F/TUBA1B/TAP1/CALR/HLA-DMA/TUBA1C/HLA-DQA1/TLR2/ACTB/HLA-DQA2/FCGR2A/ATP6V1E1/HLA-DMB	39
hsa03010	Ribosome	28/556	91/5868	8.31521936376475e-09	3.24125706444033e-07	6235/6168/6218/6227/3921/6222/6192/9349/6232/6160/6175/25873/6157/6228/6206/6234/6193/6181/6208/11224/6125/6167/6233/6141/6201/6217/6188/4736	RPS29/RPL37A/RPS17/RPS21/RPSA/RPS18/RPS4Y1/RPL23/RPS27/RPL31/RPLP0/RPL36/RPL27A/RPS23/RPS12/RPS28/RPS5/RPLP2/RPS14/RPL35/RPL5/RPL37/RPS27A/RPL18/RPS7/RPS16/RPS3/RPL10A	28
hsa05016	Huntington's disease	43/556	183/5868	9.87184892722945e-09	3.24125706444033e-07	6648/1345/6647/27089/5441/2876/7019/7052/292/29796/1350/1211/4713/4725/1327/1213/4706/4700/4718/161/4716/4726/3066/4708/4715/4705/1347/5438/4707/54539/5440/126328/64764/54205/4698/4722/4728/5435/7416/4729/4697/10975/1337	SOD2/COX6C/SOD1/UQCRQ/POLR2L/GPX1/TFAM/TGM2/SLC25A5/UQCR10/COX7C/CLTA/NDUFB7/NDUFS5/COX4I1/CLTC/NDUFAB1/NDUFA6/NDUFC2/AP2A2/NDUFB10/NDUFS6/HDAC2/NDUFB2/NDUFB9/NDUFA10/COX7A2/POLR2I/NDUFB1/NDUFB11/POLR2K/NDUFA11/CREB3L2/CYCS/NDUFA5/NDUFS3/NDUFS8/POLR2F/VDAC1/NDUFV2/NDUFA4/UQCR11/COX6A1	43
hsa05012	Parkinson's disease	32/556	130/5868	2.6317766732894e-07	7.40657149482874e-06	1345/27089/9246/7314/292/29796/1350/4713/4725/1327/4706/4700/4718/11315/4716/4726/4708/4715/4705/1347/4707/54539/126328/54205/4698/4722/4728/7416/4729/4697/10975/1337	COX6C/UQCRQ/UBE2L6/UBB/SLC25A5/UQCR10/COX7C/NDUFB7/NDUFS5/COX4I1/NDUFAB1/NDUFA6/NDUFC2/PARK7/NDUFB10/NDUFS6/NDUFB2/NDUFB9/NDUFA10/COX7A2/NDUFB1/NDUFB11/NDUFA11/CYCS/NDUFA5/NDUFS3/NDUFS8/VDAC1/NDUFV2/NDUFA4/UQCR11/COX6A1	32
hsa05330	Allograft rejection	14/556	37/5868	3.11484032243129e-06	7.67029429398706e-05	3106/3105/3107/3133/3113/3122/3134/3123/3115/942/3108/3117/3118/3109	HLA-B/HLA-A/HLA-C/HLA-E/HLA-DPA1/HLA-DRA/HLA-F/HLA-DRB1/HLA-DPB1/CD86/HLA-DMA/HLA-DQA1/HLA-DQA2/HLA-DMB	14
hsa00190	Oxidative phosphorylation	30/556	132/5868	3.76583689353916e-06	8.11072623533345e-05	525/1345/245973/27089/29796/1350/9296/4713/4725/1327/4706/4700/4718/4716/4726/4708/4715/4705/1347/4707/54539/126328/4698/4722/4728/529/4729/4697/10975/1337	ATP6V1B1/COX6C/ATP6V1C2/UQCRQ/UQCR10/COX7C/ATP6V1F/NDUFB7/NDUFS5/COX4I1/NDUFAB1/NDUFA6/NDUFC2/NDUFB10/NDUFS6/NDUFB2/NDUFB9/NDUFA10/COX7A2/NDUFB1/NDUFB11/NDUFA11/NDUFA5/NDUFS3/NDUFS8/ATP6V1E1/NDUFV2/NDUFA4/UQCR11/COX6A1	30
hsa05416	Viral myocarditis	20/556	70/5868	4.22642615203782e-06	8.11072623533345e-05	4628/3106/3105/3107/1605/3133/3113/3122/3134/3123/3115/1604/942/595/3108/3117/60/54205/3118/3109	MYH10/HLA-B/HLA-A/HLA-C/DAG1/HLA-E/HLA-DPA1/HLA-DRA/HLA-F/HLA-DRB1/HLA-DPB1/CD55/CD86/CCND1/HLA-DMA/HLA-DQA1/ACTB/CYCS/HLA-DQA2/HLA-DMB	20
hsa04940	Type I diabetes mellitus	15/556	43/5868	4.52883190805421e-06	8.11072623533345e-05	3106/3105/3107/3329/3133/3113/3122/3134/3123/3115/942/3108/3117/3118/3109	HLA-B/HLA-A/HLA-C/HSPD1/HLA-E/HLA-DPA1/HLA-DRA/HLA-F/HLA-DRB1/HLA-DPB1/CD86/HLA-DMA/HLA-DQA1/HLA-DQA2/HLA-DMB	15
hsa05332	Graft-versus-host disease	14/556	41/5868	1.25586702867352e-05	0.000206171503873903	3106/3105/3107/3133/3113/3122/3134/3123/3115/942/3108/3117/3118/3109	HLA-B/HLA-A/HLA-C/HLA-E/HLA-DPA1/HLA-DRA/HLA-F/HLA-DRB1/HLA-DPB1/CD86/HLA-DMA/HLA-DQA1/HLA-DQA2/HLA-DMB	14
hsa05323	Rheumatoid arthritis	22/556	91/5868	2.70337327225479e-05	0.000409665026641687	1514/525/245973/2321/3113/3122/2353/3123/3115/7422/414062/9296/942/10673/7040/3108/3117/7097/3725/3118/529/3109	CTSL/ATP6V1B1/ATP6V1C2/FLT1/HLA-DPA1/HLA-DRA/FOS/HLA-DRB1/HLA-DPB1/VEGFA/CCL3L3/ATP6V1F/CD86/TNFSF13B/TGFB1/HLA-DMA/HLA-DQA1/TLR2/JUN/HLA-DQA2/ATP6V1E1/HLA-DMB	22
hsa05010	Alzheimer's disease	33/556	167/5868	2.93365925952847e-05	0.000412807767233649	4311/351/1345/27089/2597/348/29796/1350/4713/4725/1327/4706/4700/4718/4716/4726/4708/4715/4705/572/1347/4707/54539/126328/54205/4698/4722/4728/4035/4729/4697/10975/1337	MME/APP/COX6C/UQCRQ/GAPDH/APOE/UQCR10/COX7C/NDUFB7/NDUFS5/COX4I1/NDUFAB1/NDUFA6/NDUFC2/NDUFB10/NDUFS6/NDUFB2/NDUFB9/NDUFA10/BAD/COX7A2/NDUFB1/NDUFB11/NDUFA11/CYCS/NDUFA5/NDUFS3/NDUFS8/LRP1/NDUFV2/NDUFA4/UQCR11/COX6A1	33
hsa05320	Autoimmune thyroid disease	15/556	52/5868	5.96989788926502e-05	0.000784046589456806	3106/3105/3107/3133/3113/3122/3134/3123/3115/942/3108/3117/1081/3118/3109	HLA-B/HLA-A/HLA-C/HLA-E/HLA-DPA1/HLA-DRA/HLA-F/HLA-DRB1/HLA-DPB1/CD86/HLA-DMA/HLA-DQA1/CGA/HLA-DQA2/HLA-DMB	15
hsa04514	Cell adhesion molecules (CAMs)	27/556	133/5868	9.62200817474509e-05	0.00118470975651549	999/3106/3105/1364/3655/3107/83700/23705/1462/3133/3113/3696/3122/3688/1366/3134/5175/3123/3115/5788/942/9019/3108/3117/3385/3118/3109	CDH1/HLA-B/HLA-A/CLDN4/ITGA6/HLA-C/JAM3/CADM1/VCAN/HLA-E/HLA-DPA1/ITGB8/HLA-DRA/ITGB1/CLDN7/HLA-F/PECAM1/HLA-DRB1/HLA-DPB1/PTPRC/CD86/MPZL1/HLA-DMA/HLA-DQA1/ICAM3/HLA-DQA2/HLA-DMB	27
hsa05150	Staphylococcus aureus infection	15/556	55/5868	0.000121170979173147	0.00140016828765008	2214/3113/3122/712/713/714/3123/3115/2357/2359/3108/3117/3118/2212/3109	FCGR3A/HLA-DPA1/HLA-DRA/C1QA/C1QB/C1QC/HLA-DRB1/HLA-DPB1/FPR1/FPR3/HLA-DMA/HLA-DQA1/HLA-DQA2/FCGR2A/HLA-DMB	15
hsa04380	Osteoclast differentiation	26/556	128/5868	0.000127934158262444	0.00140016828765008	7305/2214/1535/1536/3460/4688/653361/4792/6772/2353/6688/2885/3726/7040/54209/10288/11006/126014/3716/10859/11025/3725/9021/6850/2212/11027	TYROBP/FCGR3A/CYBA/CYBB/IFNGR2/NCF2/NCF1/NFKBIA/STAT1/FOS/SPI1/GRB2/JUNB/TGFB1/TREM2/LILRB2/LILRB4/OSCAR/JAK1/LILRB1/LILRB3/JUN/SOCS3/SYK/FCGR2A/LILRA2	26
hsa00480	Glutathione metabolism	14/556	50/5868	0.000149530867273789	0.00155039899225981	4259/6611/79017/2941/2730/3417/2876/6723/51056/2950/2879/9446/290/2878	MGST3/SMS/GGCT/GSTA4/GCLM/IDH1/GPX1/SRM/LAP3/GSTP1/GPX4/GSTO1/ANPEP/GPX3	14
hsa05145	Toxoplasmosis	26/556	132/5868	0.000216171799922598	0.00212929222923759	3911/3912/3655/3915/3113/3460/2770/3122/4792/3688/6772/3123/3115/7040/3716/3108/572/3117/7097/2771/54205/3312/3118/3588/3717/3109	LAMA5/LAMB1/ITGA6/LAMC1/HLA-DPA1/IFNGR2/GNAI1/HLA-DRA/NFKBIA/ITGB1/STAT1/HLA-DRB1/HLA-DPB1/TGFB1/JAK1/HLA-DMA/BAD/HLA-DQA1/TLR2/GNAI2/CYCS/HSPA8/HLA-DQA2/IL10RB/JAK2/HLA-DMB	26
hsa05130	Pathogenic Escherichia coli infection	14/556	56/5868	0.000542463503428334	0.0050888242940658	999/3875/10383/3688/203068/929/387/10094/10376/81873/84790/8976/4691/60	CDH1/KRT18/TUBB4B/ITGB1/TUBB/CD14/RHOA/ARPC3/TUBA1B/ARPC5L/TUBA1C/WASL/NCL/ACTB	14
hsa04672	Intestinal immune network for IgA production	12/556	48/5868	0.0013362662400185	0.0114480556448748	7852/3113/3122/3123/3115/942/10673/7040/3108/3117/3118/3109	CXCR4/HLA-DPA1/HLA-DRA/HLA-DRB1/HLA-DPB1/CD86/TNFSF13B/TGFB1/HLA-DMA/HLA-DQA1/HLA-DQA2/HLA-DMB	12
hsa05310	Asthma	9/556	30/5868	0.00133657502452853	0.0114480556448748	2207/3113/3122/3123/3115/3108/3117/3118/3109	FCER1G/HLA-DPA1/HLA-DRA/HLA-DRB1/HLA-DPB1/HLA-DMA/HLA-DQA1/HLA-DQA2/HLA-DMB	9
hsa00270	Cysteine and methionine metabolism	10/556	36/5868	0.00140758060416651	0.0115538907925335	3945/3939/6611/1786/1036/55256/6723/259307/1788/4548	LDHB/LDHA/SMS/DNMT1/CDO1/ADI1/SRM/IL4I1/DNMT3A/MTR	10
hsa00010	Glycolysis / Gluconeogenesis	14/556	65/5868	0.00256632968777939	0.0202226779397016	84532/3945/3939/501/226/2597/128/2203/7167/217/5230/1738/5315/2023	ACSS1/LDHB/LDHA/ALDH7A1/ALDOA/GAPDH/ADH5/FBP1/TPI1/ALDH2/PGK1/DLD/PKM/ENO1	14
hsa04110	Cell cycle	22/556	124/5868	0.00269846192538435	0.0204460384346429	7029/1028/1021/7465/4172/896/4175/6502/5591/898/4176/23594/595/10912/7040/51529/4193/3066/7531/5885/9126/891	TFDP2/CDKN1C/CDK6/WEE1/MCM3/CCND3/MCM6/SKP2/PRKDC/CCNE1/MCM7/ORC6/CCND1/GADD45G/TGFB1/ANAPC11/MDM2/HDAC2/YWHAE/RAD21/SMC3/CCNB1	22
hsa05110	Vibrio cholerae infection	12/556	54/5868	0.00388838699848066	0.0283708236555811	525/245973/7082/2778/9601/5567/9296/30001/10945/60/11014/529	ATP6V1B1/ATP6V1C2/TJP1/GNAS/PDIA4/PRKACB/ATP6V1F/ERO1A/KDELR1/ACTB/KDELR2/ATP6V1E1	12
hsa04144	Endocytosis	31/556	201/5868	0.00414447177234737	0.029159319255444	1956/4233/3106/3105/3107/153/7852/2348/5590/7037/3133/2065/2321/3480/84612/3134/1601/387/1211/1213/161/7040/4193/84313/11059/3265/56904/9135/64744/8766/3312	EGFR/MET/HLA-B/HLA-A/HLA-C/ADRB1/CXCR4/FOLR1/PRKCZ/TFRC/HLA-E/ERBB3/FLT1/IGF1R/PARD6B/HLA-F/DAB2/RHOA/CLTA/CLTC/AP2A2/TGFB1/MDM2/VPS25/WWP1/HRAS/SH3GLB2/RABEP1/SMAP2/RAB11A/HSPA8	31
hsa00640	Propanoate metabolism	8/556	32/5868	0.00836196107747215	0.0568036666297246	84532/3945/3939/501/1892/217/5096/8802	ACSS1/LDHB/LDHA/ALDH7A1/ECHS1/ALDH2/PCCB/SUCLG1	8
hsa04540	Gap junction	16/556	90/5868	0.00959432884289665	0.063002759401688	1956/153/2697/7082/10383/2770/203068/2778/2767/5567/2885/10376/3265/84790/2771/10746	EGFR/ADRB1/GJA1/TJP1/TUBB4B/GNAI1/TUBB/GNAS/GNA11/PRKACB/GRB2/TUBA1B/HRAS/TUBA1C/GNAI2/MAP3K2	16
hsa04115	p53 signaling pathway	13/556	68/5868	0.0102930336800274	0.0654105688698516	64065/1021/6477/9538/896/27244/5366/898/595/10912/4193/54205/891	PERP/CDK6/SIAH1/EI24/CCND3/SESN1/PMAIP1/CCNE1/CCND1/GADD45G/MDM2/CYCS/CCNB1	13
hsa00620	Pyruvate metabolism	9/556	40/5868	0.0108612335671786	0.0668644691479435	84532/3945/3939/501/231/217/1738/5315/4190	ACSS1/LDHB/LDHA/ALDH7A1/AKR1B1/ALDH2/DLD/PKM/MDH1	9
hsa04141	Protein processing in endoplasmic reticulum	25/556	165/5868	0.0118383437236964	0.0706713246535814	7991/6238/3998/7184/3326/1650/6185/5034/3320/10130/3309/7415/9532/9601/10905/27102/10277/440275/64374/23193/5887/811/30001/3312/10961	TUSC3/RRBP1/LMAN1/HSP90B1/HSP90AB1/DDOST/RPN2/P4HB/HSP90AA1/PDIA6/HSPA5/VCP/BAG2/PDIA4/MAN1A2/EIF2AK1/UBE4B/EIF2AK4/SIL1/GANAB/RAD23B/CALR/ERO1A/HSPA8/ERP29	25
hsa05100	Bacterial invasion of epithelial cells	13/556	70/5868	0.0130795883317329	0.0757846735691585	999/4233/3688/387/10094/1211/81873/1213/10163/8976/391/60/23607	CDH1/MET/ITGB1/RHOA/ARPC3/CLTA/ARPC5L/CLTC/WASF2/WASL/RHOG/ACTB/CD2AP	13
hsa04666	Fc gamma R-mediated phagocytosis	16/556	94/5868	0.0144041236393496	0.0810746387700536	2214/85477/8613/653361/5788/10094/10451/81873/10163/65108/3055/7408/8976/6850/2212/4067	FCGR3A/SCIN/PLPP3/NCF1/PTPRC/ARPC3/VAV3/ARPC5L/WASF2/MARCKSL1/HCK/VASP/WASL/SYK/FCGR2A/LYN	16
hsa04640	Hematopoietic cell lineage	15/556	88/5868	0.017284070168155	0.0945822728646258	3655/4311/960/7037/100133941/966/3122/929/3123/1604/928/951/1441/290/1438	ITGA6/MME/CD44/TFRC/CD24/CD59/HLA-DRA/CD14/HLA-DRB1/CD55/CD9/CD37/CSF3R/ANPEP/CSF2RA	15
hsa04520	Adherens junction	13/556	73/5868	0.0183051275153889	0.0974624356900434	999/1956/4233/10580/7082/3480/4008/7525/387/10163/5777/8976/60	CDH1/EGFR/MET/SORBS1/TJP1/IGF1R/LMO7/YES1/RHOA/WASF2/PTPN6/WASL/ACTB	13
hsa05215	Prostate cancer	14/556	89/5868	0.0391844080183767	0.203140220516321	1956/7184/3326/3480/4792/3320/898/2950/2885/595/4193/3265/572/64764	EGFR/HSP90B1/HSP90AB1/IGF1R/NFKBIA/HSP90AA1/CCNE1/GSTP1/GRB2/CCND1/MDM2/HRAS/BAD/CREB3L2	14
hsa05020	Prion diseases	7/556	35/5868	0.04272212109185	0.21580148346396	3915/6647/712/3309/713/714/5567	LAMC1/SOD1/C1QA/HSPA5/C1QB/C1QC/PRKACB	7
hsa05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/556	74/5868	0.0439927467515318	0.215878754259461	3691/1832/1829/3655/1605/2697/1824/3693/3696/3688/60/6546	ITGB4/DSP/DSG2/ITGA6/DAG1/GJA1/DSC2/ITGB5/ITGB8/ITGB1/ACTB/SLC8A1	12
hsa04670	Leukocyte transendothelial migration	17/556	116/5868	0.0450442085126081	0.215878754259461	1364/83700/7852/1535/1536/4688/2770/653361/3688/1366/5175/387/10451/4478/7408/2771/60	CLDN4/JAM3/CXCR4/CYBA/CYBB/NCF2/GNAI1/NCF1/ITGB1/CLDN7/PECAM1/RHOA/VAV3/MSN/VASP/GNAI2/ACTB	17
hsa00071	Fatty acid degradation	8/556	43/5868	0.0460249120756211	0.215878754259461	501/128/1892/217/1632/10455/3032/37	ALDH7A1/ADH5/ECHS1/ALDH2/ECI1/ECI2/HADHB/ACADVL	8
hsa05200	Pathways in cancer	40/556	326/5868	0.0505948606127225	0.227929105202332	999/3911/1956/4233/1284/3912/3655/6513/3915/1021/2737/7184/2034/3326/3480/4792/3320/3688/6772/6502/2353/387/7422/898/2950/10342/6688/2885/595/7040/4193/3265/3066/3716/1441/572/1163/54205/3725/1438	CDH1/LAMA5/EGFR/MET/COL4A2/LAMB1/ITGA6/SLC2A1/LAMC1/CDK6/GLI3/HSP90B1/EPAS1/HSP90AB1/IGF1R/NFKBIA/HSP90AA1/ITGB1/STAT1/SKP2/FOS/RHOA/VEGFA/CCNE1/GSTP1/TFG/SPI1/GRB2/CCND1/TGFB1/MDM2/HRAS/HDAC2/JAK1/CSF3R/BAD/CKS1B/CYCS/JUN/CSF2RA	40
hsa00410	beta-Alanine metabolism	5/556	22/5868	0.0509093573576868	0.227929105202332	501/6611/1892/217/6723	ALDH7A1/SMS/ECHS1/ALDH2/SRM	5
hsa03040	Spliceosome	18/556	127/5868	0.052868733557813	0.227929105202332	6636/6627/51690/6637/4809/27258/6632/1665/84991/51639/6635/56259/6629/6633/6634/6427/3312/6631	SNRPF/SNRPA1/LSM7/SNRPG/SNU13/LSM3/SNRPD1/DHX15/RBM17/SF3B6/SNRPE/CTNNBL1/SNRPB2/SNRPD2/SNRPD3/SRSF2/HSPA8/SNRPC	18
hsa05120	Epithelial cell signaling in Helicobacter pylori infection	11/556	68/5868	0.0532220245650114	0.227929105202332	1956/4233/83700/525/245973/7082/4792/9296/3725/529/4067	EGFR/MET/JAM3/ATP6V1B1/ATP6V1C2/TJP1/NFKBIA/ATP6V1F/JUN/ATP6V1E1/LYN	11
hsa05222	Small cell lung cancer	13/556	85/5868	0.0555195149765206	0.232709456390948	3911/1284/3912/3655/3915/1021/4792/3688/6502/898/595/1163/54205	LAMA5/COL4A2/LAMB1/ITGA6/LAMC1/CDK6/NFKBIA/ITGB1/SKP2/CCNE1/CCND1/CKS1B/CYCS	13
hsa04142	Lysosome	17/556	121/5868	0.0628577901259246	0.256429273414624	1515/1514/1520/7805/1512/1174/5641/162/10053/2517/1211/1213/6556/968/3988/8905/1201	CTSV/CTSL/CTSS/LAPTM5/CTSH/AP1S1/LGMN/AP1B1/AP1M2/FUCA1/CLTA/CLTC/SLC11A1/CD68/LIPA/AP1S2/CLN3	17
hsa05142	Chagas disease (American trypanosomiasis)	15/556	104/5868	0.0643375822369124	0.256429273414624	3460/2770/4792/712/2778/2767/713/714/2353/414062/7040/811/7097/2771/3725	IFNGR2/GNAI1/NFKBIA/C1QA/GNAS/GNA11/C1QB/C1QC/FOS/CCL3L3/TGFB1/CALR/TLR2/GNAI2/JUN	15
hsa00330	Arginine and proline metabolism	9/556	54/5868	0.0650835719326458	0.256429273414624	501/445/6611/1159/217/6723/51056/2752/5033	ALDH7A1/ASS1/SMS/CKMT1B/ALDH2/SRM/LAP3/GLUL/P4HA1	9
hsa00630	Glyoxylate and dicarboxylate metabolism	4/556	18/5868	0.0837571179176233	0.323532396662192	5096/283871/4190/50	PCCB/PGP/MDH1/ACO2	4
hsa04510	Focal adhesion	25/556	200/5868	0.0898784860570023	0.340501187562105	3911/1956/4233/1284/3912/3691/3655/3915/3693/2321/3480/3696/896/3688/387/7422/10451/2316/2885/595/3265/7408/572/60/3725	LAMA5/EGFR/MET/COL4A2/LAMB1/ITGB4/ITGA6/LAMC1/ITGB5/FLT1/IGF1R/ITGB8/CCND3/ITGB1/RHOA/VEGFA/VAV3/FLNA/GRB2/CCND1/HRAS/VASP/BAD/ACTB/JUN	25
hsa04662	B cell receptor signaling pathway	11/556	75/5868	0.0941144769295369	0.349821735002241	4792/2353/10451/2885/5777/3265/10725/11025/3725/6850/4067	NFKBIA/FOS/VAV3/GRB2/PTPN6/HRAS/NFAT5/LILRB3/JUN/SYK/LYN	11
hsa05219	Bladder cancer	7/556	42/5868	0.0972707139431953	0.354857974940916	999/1956/1890/7422/595/4193/3265	CDH1/EGFR/TYMP/VEGFA/CCND1/MDM2/HRAS	7
hsa04610	Complement and coagulation cascades	10/556	69/5868	0.113784389987716	0.407285210739528	2153/5265/966/712/713/714/1604/5329/2/4179	F5/SERPINA1/CD59/C1QA/C1QB/C1QC/CD55/PLAUR/A2M/CD46	10
hsa00280	Valine, leucine and isoleucine degradation	7/556	44/5868	0.117724062765736	0.407285210739528	501/1892/217/5096/259307/1738/3032	ALDH7A1/ECHS1/ALDH2/PCCB/IL4I1/DLD/HADHB	7
hsa05131	Shigellosis	9/556	61/5868	0.119027565714063	0.407285210739528	960/4792/3688/10094/81873/10163/8976/391/60	CD44/NFKBIA/ITGB1/ARPC3/ARPC5L/WASF2/WASL/RHOG/ACTB	9
hsa03030	DNA replication	6/556	36/5868	0.119911381842095	0.407285210739528	4172/4175/4176/6119/5981/6742	MCM3/MCM6/MCM7/RPA3/RFC1/SSBP1	6
hsa04062	Chemokine signaling pathway	23/556	189/5868	0.124846426683821	0.416860102656149	55970/7852/5590/2770/653361/4792/6772/387/5567/10451/414062/9560/2885/3055/3265/8976/2268/2771/3627/58191/6351/3717/4067	GNG12/CXCR4/PRKCZ/GNAI1/NCF1/NFKBIA/STAT1/RHOA/PRKACB/VAV3/CCL3L3/CCL4L2/GRB2/HCK/HRAS/WASL/FGR/GNAI2/CXCL10/CXCL16/CCL4/JAK2/LYN	23
hsa05160	Hepatitis C	17/556	134/5868	0.129785317232468	0.426128458246603	1956/1364/4792/1366/6772/27102/2885/3659/440275/3665/4938/3265/3716/4939/572/3434/9021	EGFR/CLDN4/NFKBIA/CLDN7/STAT1/EIF2AK1/GRB2/IRF1/EIF2AK4/IRF7/OAS1/HRAS/JAK1/OAS2/BAD/IFIT1/SOCS3	17
hsa05414	Dilated cardiomyopathy	12/556	90/5868	0.141233172747041	0.453743532636368	3691/3655/1605/153/3693/3696/3688/2778/5567/7040/60/6546	ITGB4/ITGA6/DAG1/ADRB1/ITGB5/ITGB8/ITGB1/GNAS/PRKACB/TGFB1/ACTB/SLC8A1	12
hsa04650	Natural killer cell mediated cytotoxicity	17/556	136/5868	0.142802533113984	0.453743532636368	3106/3105/3107/7305/2214/3133/2207/3460/962/10451/2885/8743/5777/10870/3265/10725/6850	HLA-B/HLA-A/HLA-C/TYROBP/FCGR3A/HLA-E/FCER1G/IFNGR2/CD48/VAV3/GRB2/TNFSF10/PTPN6/HCST/HRAS/NFAT5/SYK	17
hsa00020	Citrate cycle (TCA cycle)	5/556	30/5868	0.149030099062705	0.466014754211951	3417/1738/8802/4190/50	IDH1/DLD/SUCLG1/MDH1/ACO2	5
hsa00510	N-Glycan biosynthesis	7/556	49/5868	0.177491975290091	0.539427268668125	7991/1650/6185/2530/10905/23193/4245	TUSC3/DDOST/RPN2/FUT8/MAN1A2/GANAB/MGAT1	7
hsa04512	ECM-receptor interaction	11/556	85/5868	0.177983616565625	0.539427268668125	3911/1284/3912/3691/3655/1605/3915/960/3693/3696/3688	LAMA5/COL4A2/LAMB1/ITGB4/ITGA6/DAG1/LAMC1/CD44/ITGB5/ITGB8/ITGB1	11
hsa04260	Cardiac muscle contraction	10/556	77/5868	0.189844139680174	0.56665599268173	1345/27089/6548/29796/1350/1327/1347/6546/10975/1337	COX6C/UQCRQ/SLC9A1/UQCR10/COX7C/COX4I1/COX7A2/SLC8A1/UQCR11/COX6A1	10
hsa04614	Renin-angiotensin system	3/556	17/5868	0.213827412802305	0.622031792245897	2028/4311/290	ENPEP/MME/ANPEP	3
hsa05322	Systemic lupus erythematosus	16/556	136/5868	0.214711481587416	0.622031792245897	2214/3113/3122/712/713/714/3123/3115/942/6632/3108/3117/6634/3118/2212/3109	FCGR3A/HLA-DPA1/HLA-DRA/C1QA/C1QB/C1QC/HLA-DRB1/HLA-DPB1/CD86/SNRPD1/HLA-DMA/HLA-DQA1/SNRPD3/HLA-DQA2/FCGR2A/HLA-DMB	16
hsa05218	Melanoma	9/556	71/5868	0.226865777356178	0.647718233900973	999/1956/4233/1021/3480/595/4193/3265/572	CDH1/EGFR/MET/CDK6/IGF1R/CCND1/MDM2/HRAS/BAD	9
hsa04962	Vasopressin-regulated water reabsorption	6/556	44/5868	0.234205917002013	0.65912236641995	140735/2778/5567/397/64764/8766	DYNLL2/GNAS/PRKACB/ARHGDIB/CREB3L2/RAB11A	6
hsa00670	One carbon pool by folate	3/556	18/5868	0.239841471779241	0.665475632964935	4548/471/7298	MTR/ATIC/TYMS	3
hsa04966	Collecting duct acid secretion	4/556	27/5868	0.249594696506661	0.679861673184143	525/245973/9296/529	ATP6V1B1/ATP6V1C2/ATP6V1F/ATP6V1E1	4
hsa05220	Chronic myeloid leukemia	9/556	73/5868	0.251928437271281	0.679861673184143	1021/4792/2885/595/7040/4193/3265/3066/572	CDK6/NFKBIA/GRB2/CCND1/TGFB1/MDM2/HRAS/HDAC2/BAD	9
hsa00100	Steroid biosynthesis	3/556	19/5868	0.26634079301017	0.709042381391938	1718/2222/3988	DHCR24/FDFT1/LIPA	3
hsa05214	Glioma	8/556	65/5868	0.27121970963474	0.712403770640583	1956/1021/3480/818/2885/595/4193/3265	EGFR/CDK6/IGF1R/CAMK2G/GRB2/CCND1/MDM2/HRAS	8
hsa00790	Folate biosynthesis	2/556	11/5868	0.280267208408036	0.724821810232042	8836/2643	GGH/GCH1	2
hsa04810	Regulation of actin cytoskeleton	23/556	213/5868	0.283305986740443	0.724821810232042	1956/4628/3691/3655/55970/7114/3693/85477/3696/6548/3688/929/387/10094/10451/81873/10163/4478/3265/6237/8976/60/10788	EGFR/MYH10/ITGB4/ITGA6/GNG12/TMSB4X/ITGB5/SCIN/ITGB8/SLC9A1/ITGB1/CD14/RHOA/ARPC3/VAV3/ARPC5L/WASF2/MSN/HRAS/RRAS/WASL/ACTB/IQGAP2	23
hsa03020	RNA polymerase	4/556	29/5868	0.293217108501554	0.731186966769698	5441/5438/5440/5435	POLR2L/POLR2I/POLR2K/POLR2F	4
hsa05216	Thyroid cancer	4/556	29/5868	0.293217108501554	0.731186966769698	999/10342/595/3265	CDH1/TFG/CCND1/HRAS	4
hsa04146	Peroxisome	9/556	79/5868	0.33170175907639	0.77560697648718	11001/6648/6647/5052/3417/25824/10455/1891/10654	SLC27A2/SOD2/SOD1/PRDX1/IDH1/PRDX5/ECI2/ECH1/PMVK	9
hsa00240	Pyrimidine metabolism	11/556	99/5868	0.335178414042197	0.77560697648718	1890/5441/7378/50808/7298/5438/4830/5440/5435/4860/1854	TYMP/POLR2L/UPP1/AK3/TYMS/POLR2I/NME1/POLR2K/POLR2F/PNP/DUT	11
hsa00561	Glycerolipid metabolism	6/556	50/5868	0.335331922936355	0.77560697648718	501/8613/11343/231/217/2710	ALDH7A1/PLPP3/MGLL/AKR1B1/ALDH2/GK	6
hsa04360	Axon guidance	14/556	129/5868	0.336755659210511	0.77560697648718	57556/80031/4233/2050/7852/5921/1942/8829/2770/3688/387/3265/10725/2771	SEMA6A/SEMA6D/MET/EPHB4/CXCR4/RASA1/EFNA1/NRP1/GNAI1/ITGB1/RHOA/HRAS/NFAT5/GNAI2	14
hsa05211	Renal cell carcinoma	8/556	70/5868	0.343394466667522	0.77560697648718	4233/6513/2034/7422/2885/7040/3265/3725	MET/SLC2A1/EPAS1/VEGFA/GRB2/TGFB1/HRAS/JUN	8
hsa05212	Pancreatic cancer	8/556	70/5868	0.343394466667522	0.77560697648718	1956/1021/6772/7422/595/7040/3716/572	EGFR/CDK6/STAT1/VEGFA/CCND1/TGFB1/JAK1/BAD	8
hsa05144	Malaria	6/556	51/5868	0.352784579342433	0.77560697648718	4233/5175/7040/7097/2995/4035	MET/PECAM1/TGFB1/TLR2/GYPC/LRP1	6
hsa03450	Non-homologous end-joining	2/556	13/5868	0.352880880444608	0.77560697648718	5591/10111	PRKDC/RAD50	2
hsa00040	Pentose and glucuronate interconversions	4/556	32/5868	0.360087953446293	0.77560697648718	231/217/51181/7360	AKR1B1/ALDH2/DCXR/UGP2	4
hsa00250	Alanine, aspartate and glutamate metabolism	4/556	32/5868	0.360087953446293	0.77560697648718	445/2673/259307/2752	ASS1/GFPT1/IL4I1/GLUL	4
hsa00380	Tryptophan metabolism	5/556	42/5868	0.366716020846146	0.77560697648718	501/1892/217/259307/8942	ALDH7A1/ECHS1/ALDH2/IL4I1/KYNU	5
hsa04530	Tight junction	14/556	132/5868	0.36934108279917	0.77560697648718	4628/1364/83700/5590/7082/2770/84612/7525/1366/387/3265/6237/2771/60	MYH10/CLDN4/JAM3/PRKCZ/TJP1/GNAI1/PARD6B/YES1/CLDN7/RHOA/HRAS/RRAS/GNAI2/ACTB	14
hsa05213	Endometrial cancer	6/556	52/5868	0.370304742155447	0.77560697648718	999/1956/2885/595/3265/572	CDH1/EGFR/GRB2/CCND1/HRAS/BAD	6
hsa05210	Colorectal cancer	7/556	62/5868	0.372198774846306	0.77560697648718	2353/387/595/7040/572/54205/3725	FOS/RHOA/CCND1/TGFB1/BAD/CYCS/JUN	7
hsa03060	Protein export	3/556	23/5868	0.374023668864376	0.77560697648718	3309/58477/6727	HSPA5/SRPRB/SRP14	3
hsa03430	Mismatch repair	3/556	23/5868	0.374023668864376	0.77560697648718	6119/5981/6742	RPA3/RFC1/SSBP1	3
hsa05410	Hypertrophic cardiomyopathy (HCM)	9/556	83/5868	0.387199333149938	0.794565298234769	3691/3655/1605/3693/3696/3688/7040/60/6546	ITGB4/ITGA6/DAG1/ITGB5/ITGB8/ITGB1/TGFB1/ACTB/SLC8A1	9
hsa04977	Vitamin digestion and absorption	3/556	24/5868	0.400687223205288	0.813766834757132	80704/6573/8884	SLC19A3/SLC19A1/SLC5A6	3
hsa05223	Non-small cell lung cancer	6/556	54/5868	0.40540188184681	0.814940517590015	1956/1021/2885/595/3265/572	EGFR/CDK6/GRB2/CCND1/HRAS/BAD	6
hsa00900	Terpenoid backbone biosynthesis	2/556	15/5868	0.422777376289269	0.841284274030162	2224/10654	FDPS/PMVK	2
hsa04623	Cytosolic DNA-sensing pathway	6/556	56/5868	0.440345322895363	0.866589974276589	4792/9560/29108/3665/3627/6351	NFKBIA/CCL4L2/PYCARD/IRF7/CXCL10/CCL4	6
hsa04660	T cell receptor signaling pathway	11/556	108/5868	0.447650784789089	0.866589974276589	4792/1739/2353/387/5788/10451/2885/5777/3265/10725/3725	NFKBIA/DLG1/FOS/RHOA/PTPRC/VAV3/GRB2/PTPN6/HRAS/NFAT5/JUN	11
hsa00051	Fructose and mannose metabolism	4/556	36/5868	0.448691255716812	0.866589974276589	226/2203/231/7167	ALDOA/FBP1/AKR1B1/TPI1	4
hsa04970	Salivary secretion	9/556	89/5868	0.47095705448285	0.895212854462037	4069/153/3783/6548/2778/490/5567/1471/493	LYZ/ADRB1/KCNN4/SLC9A1/GNAS/ATP2B1/PRKACB/CST3/ATP2B4	9
hsa04621	NOD-like receptor signaling pathway	6/556	58/5868	0.474881029290685	0.895212854462037	7184/3326/4792/3320/29108/7205	HSP90B1/HSP90AB1/NFKBIA/HSP90AA1/PYCARD/TRIP6	6
hsa00030	Pentose phosphate pathway	3/556	27/5868	0.478356096366504	0.895212854462037	226/22934/2203	ALDOA/RPIA/FBP1	3
hsa00360	Phenylalanine metabolism	2/556	17/5868	0.488571562755471	0.895212854462037	259307/9588	IL4I1/PRDX6	2
hsa00511	Other glycan degradation	2/556	17/5868	0.488571562755471	0.895212854462037	2517/2519	FUCA1/FUCA2	2
hsa04912	GnRH signaling pathway	10/556	101/5868	0.49146216431803	0.895212854462037	1956/2778/2767/5567/818/2885/3265/1081/3725/10746	EGFR/GNAS/GNA11/PRKACB/CAMK2G/GRB2/HRAS/CGA/JUN/MAP3K2	10
hsa04730	Long-term depression	7/556	70/5868	0.499668983827651	0.895212854462037	3480/2770/2778/2767/3265/2771/4067	IGF1R/GNAI1/GNAS/GNA11/HRAS/GNAI2/LYN	7
hsa03440	Homologous recombination	3/556	28/5868	0.503208490459136	0.895212854462037	10111/6119/6742	RAD50/RPA3/SSBP1	3
hsa04620	Toll-like receptor signaling pathway	10/556	102/5868	0.504409273326325	0.895212854462037	4792/6772/929/2353/942/3665/7097/3627/6351/3725	NFKBIA/STAT1/CD14/FOS/CD86/IRF7/TLR2/CXCL10/CCL4/JUN	10
hsa03018	RNA degradation	7/556	71/5868	0.515143055123826	0.906099838030301	3329/10950/51690/170506/27258/2023/26986	HSPD1/BTG3/LSM7/DHX36/LSM3/ENO1/PABPC1	7
hsa05146	Amoebiasis	10/556	106/5868	0.555167729577651	0.967858785192895	3911/1284/3912/3915/2778/2767/929/5567/7040/7097	LAMA5/COL4A2/LAMB1/LAMC1/GNAS/GNA11/CD14/PRKACB/TGFB1/TLR2	10
hsa04971	Gastric acid secretion	7/556	74/5868	0.560461480251588	0.968516768504937	2770/6548/2778/5567/818/2771/60	GNAI1/SLC9A1/GNAS/PRKACB/CAMK2G/GNAI2/ACTB	7
hsa05014	Amyotrophic lateral sclerosis (ALS)	5/556	53/5868	0.573030301543912	0.979199305339608	6647/2876/572/54205/7133	SOD1/GPX1/BAD/CYCS/TNFRSF1B	5
hsa04914	Progesterone-mediated oocyte maturation	8/556	86/5868	0.576584362534998	0.979199305339608	3326/3480/2770/3320/5567/51529/2771/891	HSP90AB1/IGF1R/GNAI1/HSP90AA1/PRKACB/ANAPC11/GNAI2/CCNB1	8
hsa00260	Glycine, serine and threonine metabolism	3/556	32/5868	0.595962976289572	1	2731/501/1738	GLDC/ALDH7A1/DLD	3
hsa03420	Nucleotide excision repair	4/556	44/5868	0.610548478537346	1	1642/6119/5887/5981	DDB1/RPA3/RAD23B/RFC1	4
hsa04630	Jak-STAT signaling pathway	14/556	155/5868	0.616852561843322	1	5618/3460/896/6772/2885/595/3572/5777/3716/1441/9021/3588/3717/1438	PRLR/IFNGR2/CCND3/STAT1/GRB2/CCND1/IL6ST/PTPN6/JAK1/CSF3R/SOCS3/IL10RB/JAK2/CSF2RA	14
hsa00430	Taurine and hypotaurine metabolism	1/556	10/5868	0.630741400144883	1	1036	CDO1	1
hsa03008	Ribosome biogenesis in eukaryotes	7/556	79/5868	0.631399707877143	1	25996/4809/5901/26354/55651/10528/55272	REXO2/SNU13/RAN/GNL3/NHP2/NOP56/IMP3	7
hsa05221	Acute myeloid leukemia	5/556	57/5868	0.639096400707441	1	6688/2885/595/3265/572	SPI1/GRB2/CCND1/HRAS/BAD	5
hsa00910	Nitrogen metabolism	2/556	23/5868	0.655338605908837	1	767/2752	CA8/GLUL	2
hsa04974	Protein digestion and absorption	7/556	81/5868	0.657891563047319	1	7373/1284/1803/4311/3783/6546/9056	COL14A1/COL4A2/DPP4/MME/KCNN4/SLC8A1/SLC7A7	7
hsa00290	Valine, leucine and isoleucine biosynthesis	1/556	11/5868	0.665788819318568	1	55699	IARS2	1
hsa00760	Nicotinate and nicotinamide metabolism	2/556	24/5868	0.67848873160916	1	23475/4860	QPRT/PNP	2
hsa04320	Dorso-ventral axis formation	2/556	24/5868	0.67848873160916	1	1956/2885	EGFR/GRB2	2
hsa00520	Amino sugar and nucleotide sugar metabolism	4/556	48/5868	0.679591970090629	1	2673/51706/7360/80896	GFPT1/CYB5R1/UGP2/NPL	4
hsa00053	Ascorbate and aldarate metabolism	2/556	26/5868	0.720973481536752	1	501/217	ALDH7A1/ALDH2	2
hsa04012	ErbB signaling pathway	7/556	87/5868	0.730157140771022	1	1956/2065/818/2885/3265/572/3725	EGFR/ERBB3/CAMK2G/GRB2/HRAS/BAD/JUN	7
hsa00052	Galactose metabolism	2/556	27/5868	0.740382872350372	1	231/7360	AKR1B1/UGP2	2
hsa04120	Ubiquitin mediated proteolysis	11/556	135/5868	0.745426355065474	1	1642/6477/6502/9246/10277/9886/7328/51529/4193/11059/9021	DDB1/SIAH1/SKP2/UBE2L6/UBE4B/RHOBTB1/UBE2H/ANAPC11/MDM2/WWP1/SOCS3	11
hsa00350	Tyrosine metabolism	3/556	41/5868	0.759975372769549	1	128/1312/259307	ADH5/COMT/IL4I1	3
hsa04664	Fc epsilon RI signaling pathway	6/556	79/5868	0.772331383299042	1	2207/10451/2885/3265/6850/4067	FCER1G/VAV3/GRB2/HRAS/SYK/LYN	6
hsa00340	Histidine metabolism	2/556	29/5868	0.775752151148507	1	501/217	ALDH7A1/ALDH2	2
hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/556	15/5868	0.775764374510966	1	2530	FUT8	1
hsa04722	Neurotrophin signaling pathway	10/556	127/5868	0.776433947516459	1	9500/4792/387/818/2885/397/3265/572/7531/3725	MAGED1/NFKBIA/RHOA/CAMK2G/GRB2/ARHGDIB/HRAS/BAD/YWHAE/JUN	10
hsa04060	Cytokine-cytokine receptor interaction	22/556	265/5868	0.777612700712137	1	1956/4233/655/7852/2321/5618/3460/51330/7422/414062/9560/3572/8743/10673/7040/1441/3627/58191/6351/3588/7133/1438	EGFR/MET/BMP7/CXCR4/FLT1/PRLR/IFNGR2/TNFRSF12A/VEGFA/CCL3L3/CCL4L2/IL6ST/TNFSF10/TNFSF13B/TGFB1/CSF3R/CXCL10/CXCL16/CCL4/IL10RB/TNFRSF1B/CSF2RA	22
hsa04920	Adipocytokine signaling pathway	5/556	68/5868	0.785303235495976	1	6513/4792/9021/3717/7133	SLC2A1/NFKBIA/SOCS3/JAK2/TNFRSF1B	5
hsa04340	Hedgehog signaling pathway	4/556	56/5868	0.790738837031934	1	4036/655/2737/5567	LRP2/BMP7/GLI3/PRKACB	4
hsa00512	Mucin type O-Glycan biosynthesis	2/556	30/5868	0.79180601172526	1	63917/56913	GALNT11/C1GALT1	2
hsa00310	Lysine degradation	3/556	44/5868	0.801045661098775	1	501/1892/217	ALDH7A1/ECHS1/ALDH2	3
hsa03320	PPAR signaling pathway	5/556	70/5868	0.806210698738822	1	11001/10580/4973/1622/2710	SLC27A2/SORBS1/OLR1/DBI/GK	5
hsa00980	Metabolism of xenobiotics by cytochrome P450	5/556	71/5868	0.816043090138929	1	4259/128/2941/2950/9446	MGST3/ADH5/GSTA4/GSTP1/GSTO1	5
hsa04622	RIG-I-like receptor signaling pathway	5/556	71/5868	0.816043090138929	1	9636/4792/8653/3665/3627	ISG15/NFKBIA/DDX3Y/IRF7/CXCL10	5
hsa04976	Bile secretion	5/556	71/5868	0.816043090138929	1	6513/6548/2778/5567/366	SLC2A1/SLC9A1/GNAS/PRKACB/AQP9	5
hsa00450	Selenocompound metabolism	1/556	17/5868	0.816346283994641	1	4548	MTR	1
hsa03410	Base excision repair	2/556	33/5868	0.834030000257181	1	142/328	PARP1/APEX1	2
hsa00982	Drug metabolism - cytochrome P450	5/556	73/5868	0.834506723517186	1	4259/128/2941/2950/9446	MGST3/ADH5/GSTA4/GSTP1/GSTO1	5
hsa04114	Oocyte meiosis	8/556	112/5868	0.845608432594078	1	3480/898/5567/818/51529/7531/9126/891	IGF1R/CCNE1/PRKACB/CAMK2G/ANAPC11/YWHAE/SMC3/CCNB1	8
hsa04930	Type II diabetes mellitus	3/556	48/5868	0.846491341457921	1	5590/5315/9021	PRKCZ/PKM/SOCS3	3
hsa04010	MAPK signaling pathway	21/556	268/5868	0.852780195662706	1	1956/1852/55970/1847/5921/11072/1843/929/2353/5567/2316/2885/10912/7040/3265/3925/6237/3312/3725/10746/3164	EGFR/DUSP9/GNG12/DUSP5/RASA1/DUSP14/DUSP1/CD14/FOS/PRKACB/FLNA/GRB2/GADD45G/TGFB1/HRAS/STMN1/RRAS/HSPA8/JUN/MAP3K2/NR4A1	21
hsa00230	Purine metabolism	12/556	162/5868	0.853818319406876	1	5441/10606/471/132/5315/5438/11164/4830/5440/3615/5435/4860	POLR2L/PAICS/ATIC/ADK/PKM/POLR2I/NUDT5/NME1/POLR2K/IMPDH2/POLR2F/PNP	12
hsa04310	Wnt signaling pathway	11/556	150/5868	0.854207598834112	1	4041/6477/896/6907/387/5567/818/595/8607/10725/3725	LRP5/SIAH1/CCND3/TBL1X/RHOA/PRKACB/CAMK2G/CCND1/RUVBL1/NFAT5/JUN	11
hsa04916	Melanogenesis	7/556	101/5868	0.85559659011046	1	2770/2778/5567/818/3265/2771/64764	GNAI1/GNAS/PRKACB/CAMK2G/HRAS/GNAI2/CREB3L2	7
hsa05340	Primary immunodeficiency	2/556	35/5868	0.857719456434408	1	5788/6890	PTPRC/TAP1	2
hsa04020	Calcium signaling pathway	13/556	177/5868	0.869453172948808	1	1956/153/2065/2778/490/2767/5567/292/818/493/5257/6546/7416	EGFR/ADRB1/ERBB3/GNAS/ATP2B1/GNA11/PRKACB/SLC25A5/CAMK2G/ATP2B4/PHKB/SLC8A1/VDAC1	13
hsa01040	Biosynthesis of unsaturated fatty acids	1/556	21/5868	0.876832421953329	1	9524	TECR	1
hsa00983	Drug metabolism - other enzymes	3/556	52/5868	0.882647845051553	1	1890/7378/3615	TYMP/UPP1/IMPDH2	3
hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/556	22/5868	0.888544611690622	1	79586	CHPF	1
hsa04710	Circadian rhythm	1/556	22/5868	0.888544611690622	1	79365	BHLHE41	1
hsa04964	Proximal tubule bicarbonate reclamation	1/556	23/5868	0.899144884680703	1	4190	MDH1	1
hsa00600	Sphingolipid metabolism	2/556	40/5868	0.904031746384911	1	8613/8560	PLPP3/DEGS1	2
hsa04350	TGF-beta signaling pathway	5/556	84/5868	0.910739756378553	1	655/4052/3397/387/7040	BMP7/LTBP1/ID1/RHOA/TGFB1	5
hsa04910	Insulin signaling pathway	9/556	138/5868	0.917065218714269	1	10580/5590/2203/5567/2885/3265/572/5257/9021	SORBS1/PRKCZ/FBP1/PRKACB/GRB2/HRAS/BAD/PHKB/SOCS3	9
hsa00562	Inositol phosphate metabolism	3/556	57/5868	0.917068729565162	1	51477/7167/5286	ISYNA1/TPI1/PIK3C2A	3
hsa00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	1/556	25/5868	0.917421265897748	1	8733	GPAA1	1
hsa00860	Porphyrin and chlorophyll metabolism	2/556	43/5868	0.924623440383477	1	2495/7389	FTH1/UROD	2
hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	1/556	26/5868	0.925279177272188	1	2135	EXTL2	1
hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/556	26/5868	0.925279177272188	1	6484	ST3GAL4	1
hsa04210	Apoptosis	5/556	87/5868	0.925284155621873	1	4792/5567/8743/572/54205	NFKBIA/PRKACB/TNFSF10/BAD/CYCS	5
hsa04972	Pancreatic secretion	6/556	101/5868	0.926763456072091	1	6548/2778/490/387/493/8766	SLC9A1/GNAS/ATP2B1/RHOA/ATP2B4/RAB11A	6
hsa00590	Arachidonic acid metabolism	3/556	59/5868	0.928052514028352	1	9536/2876/2878	PTGES/GPX1/GPX3	3
hsa04370	VEGF signaling pathway	4/556	76/5868	0.93860401852549	1	7422/3265/572/10725	VEGFA/HRAS/BAD/NFAT5	4
hsa00650	Butanoate metabolism	1/556	30/5868	0.949920828663869	1	1892	ECHS1	1
hsa03013	RNA transport	9/556	151/5868	0.956632604762956	1	10209/5901/8661/8894/1983/26986/8669/9669/8021	EIF1/RAN/EIF3A/EIF2S2/EIF5/PABPC1/EIF3J/EIF5B/NUP214	9
hsa04742	Taste transduction	2/556	52/5868	0.964172779888673	1	2778/5567	GNAS/PRKACB	2
hsa04140	Regulation of autophagy	1/556	34/5868	0.966445763959833	1	23710	GABARAPL1	1
hsa04720	Long-term potentiation	3/556	70/5868	0.967977108297115	1	5567/818/3265	PRKACB/CAMK2G/HRAS	3
hsa00500	Starch and sucrose metabolism	2/556	54/5868	0.96973257750138	1	178/7360	AGL/UGP2	2
hsa00565	Ether lipid metabolism	1/556	36/5868	0.972537160793845	1	8613	PLPP3	1
hsa03022	Basal transcription factors	1/556	36/5868	0.972537160793845	1	6882	TAF11	1
hsa04130	SNARE interactions in vesicular transport	1/556	36/5868	0.972537160793845	1	10791	VAMP5	1
hsa00140	Steroid hormone biosynthesis	2/556	56/5868	0.974456747646226	1	3292/1312	HSD17B1/COMT	2
hsa02010	ABC transporters	1/556	44/5868	0.987685304566263	1	6890	TAP1	1
hsa03015	mRNA surveillance pathway	3/556	83/5868	0.988298887279854	1	124540/26986/8731	MSI2/PABPC1/RNMT	3
hsa04270	Vascular smooth muscle contraction	5/556	116/5868	0.988652492335071	1	800/2778/2767/387/5567	CALD1/GNAS/GNA11/RHOA/PRKACB	5
hsa04975	Fat digestion and absorption	1/556	46/5868	0.989924546486415	1	8613	PLPP3	1
hsa04330	Notch signaling pathway	1/556	47/5868	0.99088675056638	1	3066	HDAC2	1
hsa04150	mTOR signaling pathway	1/556	52/5868	0.99448432958752	1	7422	VEGFA	1
hsa05217	Basal cell carcinoma	1/556	55/5868	0.99592001412545	1	2737	GLI3	1
hsa00564	Glycerophospholipid metabolism	2/556	80/5868	0.996877936725655	1	8613/23761	PLPP3/PISD	2
hsa00970	Aminoacyl-tRNA biosynthesis	1/556	63/5868	0.998175522786458	1	55699	IARS2	1
hsa00830	Retinol metabolism	1/556	64/5868	0.998350270302518	1	128	ADH5	1
hsa04070	Phosphatidylinositol signaling system	1/556	78/5868	0.999597820320627	1	5286	PIK3C2A	1
hsa04080	Neuroactive ligand-receptor interaction	8/556	272/5868	0.999995580308697	1	153/2564/5618/2357/2359/8698/706/1081	ADRB1/GABRE/PRLR/FPR1/FPR3/S1PR4/TSPO/CGA	8
hsa04740	Olfactory transduction	2/556	388/5868	1	1	5567/818	PRKACB/CAMK2G	2