ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0002181 cytoplasmic translation 31/580 148/18722 2.01773719366514e-17 9.38449568773656e-14 RPS21/RPS20/RPL13A/RPS11/RPLP0/RPL27A/RPL31/RPL23A/RPS3A/RPS6/RPL6/RPL7/RPS16/RPL23/RPL14/RPS13/RPS25/RPL21/RPS17/RPS10/EIF3A/RPL9/RPS26/RPL4/UBA52/EIF4G1/PKM/RPL17/EIF2S2/EIF3H/EIF4B 31 GO:0001667 ameboidal-type cell migration 44/580 475/18722 9.8163594176778e-11 2.28279438258097e-07 LAMA5/ITGB4/NRP2/GRN/RHOB/MACF1/SEMA6A/SEMA6D/ITGB1/SERPINF1/KANK1/PLEC/MET/PLPP3/ISL1/EPHB4/LRP5/GJA1/FOLR1/TPBG/TACSTD2/FERMT1/DPP4/ROCK1/RTN4/GPC3/PKN2/NR2F2/MARVELD3/EMC10/BMP7/TMSB4X/WASF2/ARID5B/FSTL1/LGMN/ID1/PFN1/GPX1/S100P/RHOA/HMGB1/CSNK2B/RAB11A 44 GO:0043434 response to peptide hormone 40/580 414/18722 2.05305550640979e-10 3.18292038677064e-07 FBN1/ATP2B1/JUND/DAG1/EGR1/TGFBR3/KANK1/SLC2A1/IQGAP1/BSG/ZFP36L1/SLC2A8/LRP5/GJA1/ESRRA/SLC9A1/BTG1/ADM/PRKDC/IGF1R/ROCK1/PHIP/POR/CSH1/VAMP2/BMP7/PTPRA/CAV1/PKM/XBP1/SRSF6/SRSF5/LEPROT/GNAI2/CCND3/HADHA/PRKCZ/IGF2/CACYBP/CYBA 40 GO:0044403 biological process involved in symbiotic interaction 32/580 290/18722 5.15837495831645e-10 5.99790048278246e-07 GAPDH/JUN/EGFR/CTSL/DAG1/ITGAV/P4HB/CD46/ITGB1/SLC3A2/BSG/ITGB5/HSPA1A/SLC1A5/SLC52A1/SLC52A2/DDB1/DPP4/TFRC/CD81/PPIA/EIF2AK4/THOC2/CFL1/CAV1/STOM/CD55/HSPA8/GPX1/SERPINB9/CDK1/DYNLT1 32 GO:0046718 viral entry into host cell 21/580 144/18722 3.67385062715269e-09 3.41741585337744e-06 EGFR/CTSL/DAG1/ITGAV/P4HB/CD46/ITGB1/SLC3A2/BSG/ITGB5/HSPA1A/SLC1A5/SLC52A1/SLC52A2/DPP4/TFRC/CD81/CAV1/CD55/CDK1/DYNLT1 21 GO:0051701 biological process involved in interaction with host 25/580 203/18722 4.41163804147626e-09 3.41975475515101e-06 EGFR/CTSL/DAG1/ITGAV/P4HB/CD46/ITGB1/SLC3A2/BSG/ITGB5/HSPA1A/SLC1A5/SLC52A1/SLC52A2/DDB1/DPP4/TFRC/CD81/PPIA/THOC2/CAV1/CD55/SERPINB9/CDK1/DYNLT1 25 GO:0052126 movement in host environment 23/580 175/18722 5.23030626769806e-09 3.47516492158053e-06 EGFR/CTSL/DAG1/ITGAV/P4HB/CD46/ITGB1/SLC3A2/BSG/ITGB5/HSPA1A/SLC1A5/SLC52A1/SLC52A2/DDB1/DPP4/TFRC/CD81/PPIA/CAV1/CD55/CDK1/DYNLT1 23 GO:0044409 entry into host 21/580 151/18722 8.76314157952698e-09 4.60447047265246e-06 EGFR/CTSL/DAG1/ITGAV/P4HB/CD46/ITGB1/SLC3A2/BSG/ITGB5/HSPA1A/SLC1A5/SLC52A1/SLC52A2/DPP4/TFRC/CD81/CAV1/CD55/CDK1/DYNLT1 21 GO:0016032 viral process 37/580 415/18722 8.90996221325997e-09 4.60447047265246e-06 JUN/EGFR/CTSL/DAG1/ITGAV/P4HB/CD46/ITGB1/SLC3A2/BSG/ITGB5/HSPA1A/SLC1A5/SLC52A1/EIF3A/SLC52A2/DDB1/DPP4/HACD3/TFRC/PKN2/CD81/PPIA/RSF1/EIF2AK4/MGAT1/CFL1/CAV1/STOM/MPHOSPH8/CD55/CANX/HSPA8/RAN/CDK1/CDC42/DYNLT1 37 GO:0043484 regulation of RNA splicing 20/580 148/18722 3.24741962650811e-08 1.46718337066527e-05 AHNAK/SON/RPS13/SLC38A2/HSPA1A/SF1/RBM25/HNRNPA1/RPS26/NPM1/POLR2A/RBM39/FUS/SRSF6/SRSF5/TRA2B/HSPA8/CIRBP/NCL/SRSF3 20 GO:0050673 epithelial cell proliferation 37/580 437/18722 3.47001012197763e-08 1.46718337066527e-05 EGFR/LAMB1/NRP2/GRN/LAMC1/LGR5/TGFBR3/SERPINF1/LGR4/NCSTN/ZFP36L1/ISL1/GJA1/PRKDC/PURA/FERMT1/RTN4/MAGED1/GPC3/TCF7L2/NR2F2/MARVELD3/EMC10/CDK6/CAV1/XBP1/SRSF6/CDKN1C/MYDGF/ID1/GPX1/HMGB1/IGF2/SERPINB1/HMGB2/CDC42/CYBA 37 GO:0048608 reproductive structure development 36/580 424/18722 4.96795206149311e-08 1.9254954198337e-05 LRP2/SPINT1/HSPA5/ADGRG1/RPS6/KRT19/SERPINF1/LGR4/SPINT2/PSAP/BSG/ZFP36L1/DHCR24/SF1/BPTF/ADAMTS1/GJA1/GLI3/ADM/CTSV/ATRX/TBX3/KDM5A/HECTD1/CITED2/NR2F2/JUNB/NIPBL/BMP7/ASPM/ARID5B/KRT8/EIF2S2/PHLDA2/IGF2/HMGB2 36 GO:0061458 reproductive system development 36/580 427/18722 5.93546228524423e-08 2.07402582128696e-05 LRP2/SPINT1/HSPA5/ADGRG1/RPS6/KRT19/SERPINF1/LGR4/SPINT2/PSAP/BSG/ZFP36L1/DHCR24/SF1/BPTF/ADAMTS1/GJA1/GLI3/ADM/CTSV/ATRX/TBX3/KDM5A/HECTD1/CITED2/NR2F2/JUNB/NIPBL/BMP7/ASPM/ARID5B/KRT8/EIF2S2/PHLDA2/IGF2/HMGB2 36 GO:0019058 viral life cycle 30/580 317/18722 6.24303622834173e-08 2.07402582128696e-05 EGFR/CTSL/DAG1/ITGAV/P4HB/CD46/ITGB1/SLC3A2/BSG/ITGB5/HSPA1A/SLC1A5/SLC52A1/SLC52A2/DDB1/DPP4/HACD3/TFRC/PKN2/CD81/PPIA/EIF2AK4/CAV1/STOM/MPHOSPH8/CD55/HSPA8/CDK1/CDC42/DYNLT1 30 GO:0051222 positive regulation of protein transport 29/580 303/18722 8.12926889663227e-08 2.52061530921578e-05 LRP1/EGFR/TCAF1/CDH1/KCNN4/WLS/SOX4/MYH10/ISL1/GJA1/B3GAT3/GLI3/KIF5B/TCF7L2/CD81/PPIA/FRMD4A/VAMP2/STOM/TPR/LEPROT/PRKCZ/DYNLL1/RAN/YWHAE/CDK1/CDC42/UBE2L3/PHPT1 29 GO:0031589 cell-substrate adhesion 32/580 363/18722 1.18552457871044e-07 3.44617175973892e-05 LAMA5/LRP1/ITGB4/LAMB1/FBLN1/CCDC80/DAG1/LAMC1/ITGAV/BCAM/MACF1/ITGA6/P4HB/ITGB1/UTRN/KANK1/IQGAP1/ITGB5/SLC9A1/TACSTD2/FERMT1/ROCK1/JAM3/CDK6/PTPRA/TRIOBP/ACTG1/ID1/RASA1/PRKCZ/RHOA/CDC42 32 GO:0030111 regulation of Wnt signaling pathway 30/580 328/18722 1.32649949602517e-07 3.62914656236063e-05 LRP1/EGFR/MACF1/EGR1/APP/LGR5/LGR4/KANK1/RNF43/WLS/SOX4/PLPP3/ZNRF3/TLE4/ISL1/FOLR1/TPBG/GLI3/DDIT3/FERMT1/GNAQ/GPC3/ATP6AP2/TCF7L2/VGLL4/NOTUM/CTNND1/ASPM/CAV1/SIAH2 30 GO:0001892 embryonic placenta development 14/580 82/18722 2.02927382410047e-07 5.24341808660628e-05 SPINT1/KRT19/SPINT2/ZFP36L1/BPTF/ADM/HECTD1/CITED2/NR2F2/JUNB/BMP7/KRT8/PHLDA2/IGF2 14 GO:1904951 positive regulation of establishment of protein localization 29/580 319/18722 2.44319521492938e-07 5.89423946329574e-05 LRP1/EGFR/TCAF1/CDH1/KCNN4/WLS/SOX4/MYH10/ISL1/GJA1/B3GAT3/GLI3/KIF5B/TCF7L2/CD81/PPIA/FRMD4A/VAMP2/STOM/TPR/LEPROT/PRKCZ/DYNLL1/RAN/YWHAE/CDK1/CDC42/UBE2L3/PHPT1 29 GO:0072001 renal system development 28/580 302/18722 2.63199420909551e-07 5.89423946329574e-05 FBN1/LRP2/LAMA5/ADAMTS6/EGR1/LGR5/FRAS1/SERPINF1/LGR4/IQGAP1/SOX4/ENPEP/ADAMTS1/PBX1/GLI3/TACSTD2/IRX2/C1GALT1/DLG5/MAGED1/GPC3/CENPF/NIPBL/BMP7/ARID5B/TFAP2A/RHOA/HPGD 28 GO:0008380 RNA splicing 35/580 434/18722 2.66134226465729e-07 5.89423946329574e-05 AHNAK/SON/ZC3H13/RPS13/SLC38A2/HSPA1A/PRPF38B/SF1/RBM25/HNRNPA1/YBX1/RPS26/NPM1/SCAF11/POLR2A/RBM39/LUC7L3/THOC2/FUS/PDCD7/SRRM2/SRSF6/SRSF5/TRA2B/PPIG/SRSF11/PNN/HSPA8/SNRPD2/HNRNPC/CIRBP/HNRNPA2B1/HNRNPA3/NCL/SRSF3 35 GO:1901653 cellular response to peptide 31/580 359/18722 2.95366117386575e-07 6.24430823620436e-05 FBN1/ATP2B1/LRP1/APP/KANK1/RPL23/ZFP36L1/SLC2A8/GJA1/ESRRA/SLC9A1/PRKDC/IGF1R/ROCK1/PHIP/POR/CSH1/VAMP2/PTPRA/CAV1/PKM/XBP1/LGMN/SRSF5/LEPROT/ID1/GNAI2/CCND3/PRKCZ/IGF2/CYBA 31 GO:0016055 Wnt signaling pathway 35/580 444/18722 4.56699197259254e-07 9.23525202805561e-05 LRP1/EGFR/MACF1/EGR1/APP/LGR5/LGR4/KANK1/RNF43/WLS/SOX4/PLPP3/ZNRF3/TLE4/ISL1/LRP5/FOLR1/TPBG/GLI3/DDIT3/DDB1/FERMT1/GNAQ/GPC3/ATP6AP2/TCF7L2/VGLL4/NOTUM/CTNND1/ASPM/CAV1/SIAH2/RHOA/CDC42/CSNK2B 35 GO:0001822 kidney development 27/580 293/18722 4.85749105964452e-07 9.25709939411208e-05 FBN1/LRP2/LAMA5/ADAMTS6/EGR1/FRAS1/SERPINF1/LGR4/IQGAP1/SOX4/ENPEP/ADAMTS1/PBX1/GLI3/TACSTD2/IRX2/C1GALT1/DLG5/MAGED1/GPC3/CENPF/NIPBL/BMP7/ARID5B/TFAP2A/RHOA/HPGD 27 GO:0198738 cell-cell signaling by wnt 35/580 446/18722 5.07599027124966e-07 9.25709939411208e-05 LRP1/EGFR/MACF1/EGR1/APP/LGR5/LGR4/KANK1/RNF43/WLS/SOX4/PLPP3/ZNRF3/TLE4/ISL1/LRP5/FOLR1/TPBG/GLI3/DDIT3/DDB1/FERMT1/GNAQ/GPC3/ATP6AP2/TCF7L2/VGLL4/NOTUM/CTNND1/ASPM/CAV1/SIAH2/RHOA/CDC42/CSNK2B 35 GO:0001890 placenta development 18/580 144/18722 5.17489968279755e-07 9.25709939411208e-05 SPINT1/RPS6/KRT19/SPINT2/BSG/ZFP36L1/BPTF/GJA1/ADM/CTSV/HECTD1/CITED2/NR2F2/JUNB/BMP7/KRT8/PHLDA2/IGF2 18 GO:0007623 circadian rhythm 22/580 210/18722 6.5457553314718e-07 0.000112756696469168 JUN/EGFR/JUND/CLDN4/EGR1/NAGLU/LGR4/MYCBP2/ADRB1/DDB1/PRKDC/GNAQ/ZFHX3/MAGED1/KDM5A/SLC6A4/NR2F6/ID1/SIAH2/TYMS/HNRNPD/CDK1 22 GO:0051384 response to glucocorticoid 18/580 148/18722 7.7947079242583e-07 0.000126399524959622 ATP2B1/FOS/EGFR/FOSB/SERPINF1/DUSP1/ZFP36L1/ISL1/ADM/CTSV/CALM1/PDCD7/AGL/TYMS/RHOA/HMGB1/PCNA/UBE2L3 18 GO:0001655 urogenital system development 29/580 338/18722 8.1398422814684e-07 0.000126399524959622 FBN1/LRP2/LAMA5/ADAMTS6/EGR1/LGR5/FRAS1/SERPINF1/LGR4/PSAP/IQGAP1/SOX4/ENPEP/ADAMTS1/PBX1/GLI3/TACSTD2/IRX2/C1GALT1/DLG5/MAGED1/GPC3/CENPF/NIPBL/BMP7/ARID5B/TFAP2A/RHOA/HPGD 29 GO:0010631 epithelial cell migration 30/580 357/18722 8.1530547168107e-07 0.000126399524959622 NRP2/GRN/RHOB/MACF1/ITGB1/SERPINF1/KANK1/MET/PLPP3/EPHB4/TACSTD2/FERMT1/DPP4/ROCK1/RTN4/PKN2/NR2F2/MARVELD3/EMC10/TMSB4X/FSTL1/LGMN/ID1/PFN1/GPX1/S100P/RHOA/HMGB1/CSNK2B/RAB11A 30 GO:0090132 epithelium migration 30/580 360/18722 9.71125034117657e-07 0.000145700081731652 NRP2/GRN/RHOB/MACF1/ITGB1/SERPINF1/KANK1/MET/PLPP3/EPHB4/TACSTD2/FERMT1/DPP4/ROCK1/RTN4/PKN2/NR2F2/MARVELD3/EMC10/TMSB4X/FSTL1/LGMN/ID1/PFN1/GPX1/S100P/RHOA/HMGB1/CSNK2B/RAB11A 30 GO:0050678 regulation of epithelial cell proliferation 31/580 381/18722 1.06818084197336e-06 0.000153104039447697 EGFR/LAMB1/NRP2/GRN/LAMC1/TGFBR3/SERPINF1/ZFP36L1/ISL1/GJA1/PRKDC/RTN4/MAGED1/GPC3/TCF7L2/NR2F2/MARVELD3/EMC10/CDK6/CAV1/XBP1/SRSF6/CDKN1C/MYDGF/ID1/GPX1/HMGB1/IGF2/HMGB2/CDC42/CYBA 31 GO:0031960 response to corticosteroid 19/580 167/18722 1.08631118077274e-06 0.000153104039447697 ATP2B1/FOS/EGFR/FOSB/SERPINF1/DUSP1/ZFP36L1/ISL1/ADM/CTSV/CALM1/PDCD7/AGL/TYMS/RHOA/HMGB1/PCNA/UBE2L3/CYBA 19 GO:0051098 regulation of binding 30/580 363/18722 1.15410917001751e-06 0.000154164346259417 JUN/LRP1/APP/TGFBR3/LRPAP1/MET/ISL1/PTPRF/DDIT3/ROCK1/CALM1/TCF7L2/NSD1/RSF1/C4orf3/EIF4G1/CAV1/TMSB4X/TXN/ID1/PHLDA2/NFKBIA/CALM2/HMGB1/RAN/STMN1/HMGB2/GMNN/CDC42/CSNK2B 30 GO:0060562 epithelial tube morphogenesis 28/580 325/18722 1.16012731005797e-06 0.000154164346259417 LRP2/LAMA5/SPINT1/DAG1/RHOB/LGR5/LGR4/MET/SPINT2/SOX4/LRP5/FOLR1/PBX1/GLI3/ADM/TACSTD2/IRX2/LMO4/TBX3/DLG5/MAGED1/GPC3/HECTD1/CITED2/BMP7/PFN1/RHOA/CSNK2B 28 GO:0060828 regulation of canonical Wnt signaling pathway 24/580 253/18722 1.250963293732e-06 0.000161617507754098 EGFR/EGR1/LGR5/LGR4/KANK1/WLS/SOX4/ZNRF3/TLE4/ISL1/FOLR1/TPBG/GLI3/DDIT3/FERMT1/GNAQ/GPC3/ATP6AP2/TCF7L2/NOTUM/CTNND1/ASPM/CAV1/SIAH2 24 GO:0090130 tissue migration 30/580 365/18722 1.29327328106865e-06 0.000162567946763521 NRP2/GRN/RHOB/MACF1/ITGB1/SERPINF1/KANK1/MET/PLPP3/EPHB4/TACSTD2/FERMT1/DPP4/ROCK1/RTN4/PKN2/NR2F2/MARVELD3/EMC10/TMSB4X/FSTL1/LGMN/ID1/PFN1/GPX1/S100P/RHOA/HMGB1/CSNK2B/RAB11A 30 GO:0010810 regulation of cell-substrate adhesion 22/580 221/18722 1.55412384064811e-06 0.000190216578496167 LRP1/FBLN1/CCDC80/DAG1/MACF1/ITGA6/P4HB/UTRN/KANK1/IQGAP1/SLC9A1/TACSTD2/FERMT1/ROCK1/CDK6/PTPRA/TRIOBP/ACTG1/RASA1/PRKCZ/RHOA/CDC42 22 GO:0045787 positive regulation of cell cycle 27/580 313/18722 1.75654919358591e-06 0.000209479751265847 EGFR/DYNC1H1/APP/PPP1R10/LRP5/ADAMTS1/PBX1/ATRX/PHIP/TBX3/NPM1/PKN2/CITED2/BRD4/SLC6A4/EIF4G1/TPR/LGMN/CCND3/RHOA/CKS1B/IGF2/CDK1/CDC42/ANAPC11/RANBP1/RAB11A 27 GO:0009409 response to cold 10/580 49/18722 2.08384086830819e-06 0.000242298596962535 ATP2B1/FOS/ADRB1/SLC9A1/ADM/EIF2AK4/ACADVL/NFKBIA/PLAC8/CIRBP 10 GO:0048511 rhythmic process 26/580 298/18722 2.20938242900974e-06 0.000250630187251812 JUN/EGFR/JUND/CLDN4/HSPA5/EGR1/NAGLU/SERPINF1/LGR4/MYCBP2/ADAMTS1/ADRB1/DDB1/PRKDC/GNAQ/ZFHX3/MAGED1/KDM5A/SLC6A4/NR2F6/ID1/SIAH2/TYMS/HNRNPD/PCNA/CDK1 26 GO:0048732 gland development 33/580 436/18722 2.37799593065651e-06 0.000263334739844844 LAMA5/EGFR/DAG1/CDH1/TGFBR3/SERPINF1/RPS16/MET/PSAP/WLS/ISL1/LRP5/LSR/PBX1/GLI3/PRKDC/RTN4/LMO4/TBX3/CITED2/PRLR/BMP7/CAV1/ARID5B/XBP1/SRSF5/TYMS/GPX1/HNRNPD/IGF2/PCNA/CDC42/CSNK2B 33 GO:0048545 response to steroid hormone 28/580 339/18722 2.65136962629429e-06 0.000286779537951041 ATP2B1/FOS/EGFR/FOSB/CLDN4/SERPINF1/UFL1/DUSP1/ZFP36L1/ISL1/ESRRA/ADM/CTSV/CALM1/BMP7/CAV1/PDCD7/AGL/PTGES3/TYMS/RHOA/HMGB1/YWHAH/TXNIP/PCNA/HMGB2/UBE2L3/CYBA 28 GO:0033157 regulation of intracellular protein transport 22/580 229/18722 2.80562385536868e-06 0.000296567194348176 TCAF1/CDH1/LMAN1/B3GAT3/GLI3/FERMT1/GCC2/OS9/KIF5B/TCF7L2/CD81/NUCB1/VAMP2/STOM/TPR/TXN/LEPROT/RAN/YWHAE/CDK1/CDC42/UBE2L3 22 GO:0009749 response to glucose 21/580 212/18722 2.89721236645858e-06 0.000299442993697753 LRP1/LDHA/EGR1/SERPINF1/SOX4/LRP5/GJA1/CTSV/IGF1R/HMGCR/KIF5B/TCF7L2/HMGN3/VAMP2/XBP1/TRA2B/DYNLL1/RHOA/TXNIP/PHPT1/CYBA 21 GO:0060070 canonical Wnt signaling pathway 26/580 303/18722 3.00374811304976e-06 0.00030370505377814 EGFR/EGR1/LGR5/LGR4/KANK1/WLS/SOX4/PLPP3/ZNRF3/TLE4/ISL1/LRP5/FOLR1/TPBG/GLI3/DDIT3/FERMT1/GNAQ/GPC3/ATP6AP2/TCF7L2/NOTUM/CTNND1/ASPM/CAV1/SIAH2 26 GO:0031099 regeneration 20/580 198/18722 3.69073585168178e-06 0.000365225796727063 LRP1/EGFR/GRN/DAG1/TGFBR3/RPS16/ISL1/PTPRF/FOLR1/GLI3/ADM/JAM3/CD81/SRSF5/NINJ1/TYMS/GPX1/PCNA/CDK1/CSNK2B 20 GO:0051592 response to calcium ion 17/580 149/18722 3.82351936401969e-06 0.000370483095042825 FOS/EGFR/FOSB/JUND/HSPA5/DUSP1/IQGAP1/NCSTN/CALM1/JUNB/FUS/CAV1/LGMN/CALM2/HNRNPD/TXNIP/CACYBP 17 GO:0071375 cellular response to peptide hormone stimulus 25/580 290/18722 4.27849228644785e-06 0.000406107502536101 FBN1/ATP2B1/KANK1/ZFP36L1/SLC2A8/ESRRA/SLC9A1/PRKDC/IGF1R/ROCK1/PHIP/POR/CSH1/VAMP2/PTPRA/CAV1/PKM/XBP1/SRSF5/LEPROT/GNAI2/CCND3/PRKCZ/IGF2/CYBA 25 GO:0090068 positive regulation of cell cycle process 22/580 236/18722 4.5915970687369e-06 0.000427110359333906 EGFR/DYNC1H1/APP/PPP1R10/LRP5/ADAMTS1/PBX1/ATRX/PHIP/NPM1/PKN2/BRD4/EIF4G1/TPR/CCND3/RHOA/IGF2/CDK1/CDC42/ANAPC11/RANBP1/RAB11A 22 GO:0009746 response to hexose 21/580 219/18722 4.84660854733117e-06 0.000441991693208574 LRP1/LDHA/EGR1/SERPINF1/SOX4/LRP5/GJA1/CTSV/IGF1R/HMGCR/KIF5B/TCF7L2/HMGN3/VAMP2/XBP1/TRA2B/DYNLL1/RHOA/TXNIP/PHPT1/CYBA 21 GO:0034976 response to endoplasmic reticulum stress 23/580 256/18722 5.20630111027537e-06 0.000465663585844053 JUN/HSP90B1/HSPA5/P4HB/UFL1/HSPA1A/ERP29/TMEM259/DDIT3/PPP1R15A/PDIA3/OS9/PMAIP1/PDIA4/DNAJB14/EIF4G1/EIF2AK4/CAV1/XBP1/CCDC47/HM13/CANX/UBXN4 23 GO:0021762 substantia nigra development 9/580 44/18722 6.64648823449893e-06 0.000568581617214177 HSPA5/CALM1/CALM2/DYNLL1/RHOA/YWHAE/YWHAH/CDC42/YWHAQ 9 GO:0045785 positive regulation of cell adhesion 32/580 437/18722 6.71659212725117e-06 0.000568581617214177 CCDC80/DAG1/ITGAV/ADGRG1/ITGA6/P4HB/CD46/UTRN/IQGAP1/SOX4/PLPP3/NFAT5/GLI3/FERMT1/DPP4/ROCK1/ZFHX3/TFRC/CITED2/CD81/CDK6/BMP7/CAV1/IL6ST/TRIOBP/XBP1/CD55/PRKCZ/RHOA/HMGB1/IGF2/CDC42 32 GO:0048736 appendage development 18/580 172/18722 6.84596227993849e-06 0.000568581617214177 FBN2/ITGB4/ITGA6/FRAS1/SOX4/ZNRF3/LRP5/PBX1/GLI3/SMOC1/ATRX/TBX3/GPC3/NR2F2/NIPBL/BMP7/TFAP2A/SLC39A1 18 GO:0060173 limb development 18/580 172/18722 6.84596227993849e-06 0.000568581617214177 FBN2/ITGB4/ITGA6/FRAS1/SOX4/ZNRF3/LRP5/PBX1/GLI3/SMOC1/ATRX/TBX3/GPC3/NR2F2/NIPBL/BMP7/TFAP2A/SLC39A1 18 GO:0007044 cell-substrate junction assembly 13/580 95/18722 7.21069200405203e-06 0.000588367166856947 LRP1/ITGB4/LAMC1/MACF1/ITGA6/PLEC/IQGAP1/DST/SLC9A1/ROCK1/PTPRA/ACTG1/RHOA 13 GO:0034284 response to monosaccharide 21/580 225/18722 7.39275278191566e-06 0.000592822296356719 LRP1/LDHA/EGR1/SERPINF1/SOX4/LRP5/GJA1/CTSV/IGF1R/HMGCR/KIF5B/TCF7L2/HMGN3/VAMP2/XBP1/TRA2B/DYNLL1/RHOA/TXNIP/PHPT1/CYBA 21 GO:0052547 regulation of peptidase activity 33/580 461/18722 7.77367880450209e-06 0.000612803052876936 GAPDH/LRP1/SPINT1/GRN/FBLN1/ITIH5/APLP2/CLDN4/CTSD/CRIM1/APP/SERPINF1/SPINT2/NCSTN/DHCR24/SERPINH1/ROCK1/POR/PMAIP1/GPC3/CAV1/ASPH/LGMN/TIMP3/SIAH2/S100A9/ARL6IP5/GPX1/RHOA/SERPINB9/HMGB1/SERPINB1/TFPI2 33 GO:0003018 vascular process in circulatory system 23/580 263/18722 8.13707909314242e-06 0.000630759247703423 LRP2/ATP2B1/LRP1/EGFR/SOD3/SLC2A1/PLEC/SLC38A2/SLC1A5/GJA5/GJA1/ADRB1/SLC38A1/ADM/ROCK1/SLC19A1/HMGCR/TFRC/SLC16A12/SLC6A4/CAV1/GPX1/RHOA 23 GO:0032868 response to insulin 23/580 264/18722 8.66035396369917e-06 0.000658080316958666 ATP2B1/EGR1/KANK1/SLC2A1/ZFP36L1/SLC2A8/ESRRA/SLC9A1/ADM/PRKDC/IGF1R/PHIP/VAMP2/PTPRA/PKM/XBP1/SRSF6/SRSF5/GNAI2/CCND3/HADHA/PRKCZ/IGF2 23 GO:0042060 wound healing 31/580 422/18722 8.77251766317723e-06 0.000658080316958666 F5/EGFR/FBLN1/DAG1/CLDN4/MACF1/LMAN1/ITGB1/KANK1/PLEC/PLPP3/ANXA5/GJA1/DST/ERBB3/GLI3/FERMT1/GNAQ/HMGCR/PPIA/CAV1/IL6ST/ACTG1/DSP/XBP1/SRSF6/GPX1/RHOA/HMGB1/TFPI2/MYL12A 31 GO:0007565 female pregnancy 19/580 193/18722 9.33556931156819e-06 0.000689202109017518 ITGB4/FOS/FBLN1/FOSB/CLDN4/SLC2A1/BSG/SLC38A2/GJA1/MAGED2/SLC38A1/ADM/CTSV/SLC19A1/CITED2/NR2F2/JUNB/PRLR/HPGD 19 GO:0001649 osteoblast differentiation 21/580 229/18722 9.70699074867974e-06 0.000705425218314211 FBN2/RRBP1/JUND/CRIM1/LGR4/UFL1/LRP5/ESRRA/ATP6AP1/GLI3/SMOC1/JUNB/CDK6/BMP7/IL6ST/CCDC47/TPM4/ATRAID/HNRNPC/IGF2/FBL 21 GO:0061337 cardiac conduction 13/580 98/18722 1.02015277279207e-05 0.000729816928583194 ATP2B1/AKAP9/DSG2/GJA5/ISL1/GJA1/SLC9A1/CALM1/DSC2/CAV1/DSP/CALM2/YWHAE 13 GO:0006457 protein folding 20/580 212/18722 1.03564646928598e-05 0.000729816928583194 HSP90B1/GRN/HSPA5/P4HB/LMAN1/HSPA1A/ERP29/NKTR/SIL1/PDIA3/PPIA/PDIA4/DNAJB14/MPDU1/CCDC47/DNAJB1/PPIG/CANX/PTGES3/HSPA8 20 GO:0034975 protein folding in endoplasmic reticulum 5/580 11/18722 1.10991336521633e-05 0.000756120763988578 HSP90B1/HSPA5/P4HB/PDIA3/CANX 5 GO:0051651 maintenance of location in cell 20/580 213/18722 1.11060585505919e-05 0.000756120763988578 AKAP9/HSP90B1/GAA/HSPA5/FTH1/GPAA1/GJA1/DDIT3/DIAPH1/CALM1/OS9/ARHGAP21/GSTO1/ASPM/CAV1/TMSB4X/TXN/S100A9/CALM2/CYBA 20 GO:0051235 maintenance of location 26/580 326/18722 1.12174441443156e-05 0.000756120763988578 FBN1/FBN2/AKAP9/HSP90B1/GAA/HSPA5/ITGAV/LTBP1/FTH1/GPAA1/GJA1/DDIT3/DIAPH1/CALM1/OS9/ARHGAP21/GSTO1/ASPM/CAV1/TMSB4X/TXN/PLIN2/NFKBIA/S100A9/CALM2/CYBA 26 GO:0001503 ossification 30/580 408/18722 1.20072494476898e-05 0.000797795959731503 FBN2/RRBP1/ATP2B1/EGFR/SLC26A2/JUND/CRIM1/LGR4/UFL1/LRP5/ESRRA/ATP6AP1/PBX1/GLI3/SMOC1/GPC3/JUNB/NOTUM/NIPBL/CDK6/BMP7/IL6ST/CCDC47/TFAP2A/TPM4/ATRAID/HNRNPC/RHOA/IGF2/FBL 30 GO:0098901 regulation of cardiac muscle cell action potential 7/580 27/18722 1.36680898649843e-05 0.000894641115129595 AKAP9/DSG2/GJA5/CALM1/DSC2/CAV1/DSP 7 GO:0009743 response to carbohydrate 22/580 253/18722 1.39406311884282e-05 0.000894641115129595 LRP1/LDHA/EGR1/SERPINF1/SOX4/ZFP36L1/LRP5/GJA1/CTSV/IGF1R/HMGCR/KIF5B/TCF7L2/HMGN3/VAMP2/XBP1/TRA2B/DYNLL1/RHOA/TXNIP/PHPT1/CYBA 22 GO:0033120 positive regulation of RNA splicing 8/580 37/18722 1.41096442494484e-05 0.000894641115129595 SLC38A2/HSPA1A/POLR2A/SRSF5/TRA2B/HSPA8/CIRBP/NCL 8 GO:0150115 cell-substrate junction organization 13/580 101/18722 1.42342383400538e-05 0.000894641115129595 LRP1/ITGB4/LAMC1/MACF1/ITGA6/PLEC/IQGAP1/DST/SLC9A1/ROCK1/PTPRA/ACTG1/RHOA 13 GO:0045216 cell-cell junction organization 19/580 200/18722 1.55354786830965e-05 0.000963406818067759 SVEP1/CLDN4/CDH1/PLEC/DSG2/GJA5/GJA1/LSR/ROCK1/DLG5/PKN2/JAM3/MARVELD3/CTNND1/CAV1/ACTG1/DSP/RHOA/CDC42 19 GO:0071559 response to transforming growth factor beta 22/580 256/18722 1.67622956079141e-05 0.00102580837990011 FBN1/FBN2/JUN/FOS/COL4A2/GLG1/HSPA5/PEG10/LTBP1/TGFBR3/ITGB5/HSPA1A/ZFP36L1/FOLR1/FERMT1/ROCK1/ZFHX3/CITED2/CAV1/CDKN1C/ID1/HPGD 22 GO:0051101 regulation of DNA binding 14/580 118/18722 1.73277507107007e-05 0.00103693343086254 JUN/ISL1/DDIT3/CALM1/NSD1/RSF1/TMSB4X/TXN/ID1/NFKBIA/CALM2/HMGB1/HMGB2/CSNK2B 14 GO:0003279 cardiac septum development 13/580 103/18722 1.76450978609642e-05 0.00103693343086254 LRP2/ADAMTS6/NRP2/TGFBR3/SOX4/GJA5/ISL1/TRIP11/LMO4/TBX3/HECTD1/CITED2/BMP7 13 GO:0044706 multi-multicellular organism process 20/580 220/18722 1.78750960231953e-05 0.00103693343086254 ITGB4/FOS/FBLN1/FOSB/CLDN4/SLC2A1/BSG/SLC38A2/GJA1/MAGED2/SLC38A1/ADM/CTSV/SLC19A1/CITED2/NR2F2/JUNB/SLC6A4/PRLR/HPGD 20 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 27/580 355/18722 1.79703041596447e-05 0.00103693343086254 FBN1/FBN2/LRP2/JUN/LRP1/FOS/GLG1/HSPA5/PEG10/EGR1/CRIM1/LTBP1/TGFBR3/ITGB5/HSPA1A/SPTBN1/FOLR1/FERMT1/GPC3/CITED2/BMP7/CAV1/FSTL1/CDKN1C/ID1/HPGD/CSNK2B 27 GO:0032970 regulation of actin filament-based process 29/580 396/18722 1.80588277574427e-05 0.00103693343086254 AKAP9/LRP1/RHOB/IQGAP2/KANK1/MET/IQGAP1/SPTAN1/DSG2/SPTBN1/GJA5/SLC9A1/TACSTD2/ROCK1/JAM3/DSC2/CAV1/TMSB4X/WASF2/TRIOBP/ACTG1/DSP/ID1/PFN1/RASA1/RHOA/STMN1/CDC42/PHPT1 29 GO:0007568 aging 26/580 339/18722 2.21747601042604e-05 0.00124860806349022 JUN/ATP2B1/LRP1/FOS/COL4A2/JUND/DAG1/RPN2/APP/SERPINF1/CTSC/YBX1/ADM/PRKDC/CTSV/HMGCR/TBX3/YPEL3/NPM1/CITED2/CDK6/MIF/CANX/TYMS/CDK1/CACYBP 26 GO:0030178 negative regulation of Wnt signaling pathway 17/580 170/18722 2.22821907696598e-05 0.00124860806349022 LRP1/EGR1/RNF43/ZNRF3/TLE4/ISL1/TPBG/GLI3/DDIT3/FERMT1/GPC3/TCF7L2/VGLL4/NOTUM/CTNND1/CAV1/SIAH2 17 GO:0006091 generation of precursor metabolites and energy 33/580 490/18722 2.69727310621955e-05 0.00149345443059847 GAPDH/COX6A1/GAA/LDHA/APP/PLEC/ALDOA/ENO1/GLDC/IL10RB/ACSS1/POR/TPI1/CROT/IL6ST/ASPH/PKM/NDUFB9/DEGS1/AGL/ACADVL/PHLDA2/PTGES3/RHOA/HMGB1/UQCRH/IGF2/COX8C/PYGL/DHRS2/CDK1/UGP2/CYBA 33 GO:1900115 extracellular regulation of signal transduction 5/580 13/18722 2.93633725329106e-05 0.00158801215872753 FBN1/FBN2/LTBP1/CD46/LRPAP1 5 GO:1900116 extracellular negative regulation of signal transduction 5/580 13/18722 2.93633725329106e-05 0.00158801215872753 FBN1/FBN2/LTBP1/CD46/LRPAP1 5 GO:0031333 negative regulation of protein-containing complex assembly 15/580 140/18722 2.99093041970843e-05 0.00159894452667401 RPL13A/HSPA5/KANK1/SPTAN1/SPTBN1/ISL1/LMO4/JAM3/TMSB4X/TRIOBP/PFN1/PRKCZ/HMGB1/STMN1/CDC42 15 GO:0003015 heart process 21/580 251/18722 3.85564186874361e-05 0.00201655261540568 ATP2B1/AKAP9/GAA/DSG2/GJA5/ISL1/GJA1/ADRB1/SLC9A1/ADM/CALM1/DSC2/GSTO1/CAV1/DSP/CYP2J2/GNAI2/GPX1/CALM2/YWHAE/CDC42 21 GO:0090316 positive regulation of intracellular protein transport 16/580 160/18722 3.85880848787585e-05 0.00201655261540568 TCAF1/CDH1/B3GAT3/GLI3/KIF5B/TCF7L2/CD81/VAMP2/STOM/TPR/LEPROT/RAN/YWHAE/CDK1/CDC42/UBE2L3 16 GO:0007160 cell-matrix adhesion 20/580 233/18722 4.08433557914817e-05 0.00210232809746783 LRP1/ITGB4/DAG1/ITGAV/BCAM/MACF1/ITGB1/UTRN/IQGAP1/ITGB5/SLC9A1/FERMT1/ROCK1/JAM3/CDK6/PTPRA/ACTG1/RASA1/PRKCZ/RHOA 20 GO:0007346 regulation of mitotic cell cycle 31/580 457/18722 4.11334888990696e-05 0.00210232809746783 EGFR/APP/DUSP1/IQGAP1/SOX4/ZFP36L1/PPP1R10/LRP5/ADAMTS1/PBX1/BTG1/DDB1/PRKDC/PHIP/PKN2/CENPF/BRD4/EIF4G1/BMP7/TPR/LGMN/CTDSPL/CDKN1C/CCND3/CKS1B/IGF2/YWHAE/CDK1/CDC42/ANAPC11/RAB11A 31 GO:0010038 response to metal ion 27/580 373/18722 4.27030235937997e-05 0.00215882350798655 JUN/FOS/EGFR/FOSB/JUND/HSPA5/CDH1/APP/SOD3/SERPINF1/DUSP1/IQGAP1/BSG/NCSTN/CALM1/JUNB/FUS/CAV1/HSD17B1/LGMN/TFAP2A/CALM2/HNRNPD/TXNIP/PCNA/CDK1/CACYBP 27 GO:0001952 regulation of cell-matrix adhesion 14/580 128/18722 4.35177358675493e-05 0.0021763547260212 LRP1/DAG1/MACF1/UTRN/IQGAP1/SLC9A1/FERMT1/ROCK1/CDK6/PTPRA/ACTG1/RASA1/PRKCZ/RHOA 14 GO:0007179 transforming growth factor beta receptor signaling pathway 18/580 198/18722 4.64537767079145e-05 0.00229847356881394 FBN1/FBN2/JUN/FOS/GLG1/HSPA5/PEG10/LTBP1/TGFBR3/ITGB5/HSPA1A/FOLR1/FERMT1/CITED2/CAV1/CDKN1C/ID1/HPGD 18 GO:1903522 regulation of blood circulation 21/580 256/18722 5.14198108380116e-05 0.00251740568639571 ATP2B1/AKAP9/EGFR/GAA/DSG2/GJA5/ISL1/GJA1/ADRB1/SLC9A1/ADM/HMGCR/CALM1/DSC2/GSTO1/CAV1/DSP/CYP2J2/CALM2/RHOA/YWHAE 21 GO:0032869 cellular response to insulin stimulus 18/580 203/18722 6.43746650011761e-05 0.00311881840542156 ATP2B1/KANK1/ZFP36L1/SLC2A8/ESRRA/SLC9A1/PRKDC/IGF1R/PHIP/VAMP2/PTPRA/PKM/XBP1/SRSF5/GNAI2/CCND3/PRKCZ/IGF2 18 GO:0060047 heart contraction 20/580 241/18722 6.5640092138451e-05 0.00314690130089326 ATP2B1/AKAP9/GAA/DSG2/GJA5/ISL1/GJA1/ADRB1/SLC9A1/ADM/CALM1/DSC2/GSTO1/CAV1/DSP/CYP2J2/GPX1/CALM2/YWHAE/CDC42 20 GO:0061008 hepaticobiliary system development 15/580 150/18722 6.68829343460032e-05 0.00314690130089326 EGFR/TGFBR3/RPS16/MET/LSR/GLI3/CITED2/NIPBL/ARID5B/XBP1/SRSF5/TYMS/HNRNPD/PCNA/CSNK2B 15 GO:0048024 regulation of mRNA splicing, via spliceosome 12/580 101/18722 6.75116206169723e-05 0.00314690130089326 SON/SF1/RBM25/HNRNPA1/NPM1/RBM39/SRSF6/TRA2B/HSPA8/CIRBP/NCL/SRSF3 12 GO:0043666 regulation of phosphoprotein phosphatase activity 9/580 58/18722 6.78995458268444e-05 0.00314690130089326 HSP90B1/SLC39A10/BOD1L1/PPP1R15A/ROCK1/CALM1/GNAI2/CALM2/CSNK2B 9 GO:0030198 extracellular matrix organization 23/580 301/18722 6.90139610172247e-05 0.00314690130089326 ADAMTSL4/COL14A1/LRP1/COL4A2/ADAMTS6/SPINT1/LAMB1/VWA1/FBLN1/CCDC80/DAG1/LAMC1/APP/ITGB1/SPINT2/SERPINH1/MMP15/ADAMTS1/CTSV/SMOC1/FERMT1/DPP4/CAV1 23 GO:0042063 gliogenesis 23/580 301/18722 6.90139610172247e-05 0.00314690130089326 LRP2/LRP1/ITGB4/EGFR/SPINT1/LAMB1/GRN/DAG1/ADGRG1/APP/UFL1/PLEC/SOX4/NCSTN/GPC1/ERBB3/GLI3/RTN4/CDK6/IL6ST/S100A9/RHOA/CDK1 23 GO:0014706 striated muscle tissue development 27/580 384/18722 7.00795731753244e-05 0.00316446694017897 LRP2/FOS/EGR1/TGFBR3/ITGB1/PLEC/GPC1/DSG2/GJA5/ISL1/GJA1/SLC9A1/HMGCR/TBX3/CITED2/NR2F2/CENPF/VGLL4/BMP7/CAV1/DSP/GPX1/RHOA/IGF2/CDK1/CDC42/CACYBP 27 GO:1903036 positive regulation of response to wounding 10/580 72/18722 7.17780560841581e-05 0.00320999748891749 LRP1/GRN/CLDN4/ITGB1/KANK1/PLPP3/FERMT1/ACTG1/XBP1/HMGB1 10 GO:0043062 extracellular structure organization 23/580 302/18722 7.25845344723059e-05 0.00321514923648281 ADAMTSL4/COL14A1/LRP1/COL4A2/ADAMTS6/SPINT1/LAMB1/VWA1/FBLN1/CCDC80/DAG1/LAMC1/APP/ITGB1/SPINT2/SERPINH1/MMP15/ADAMTS1/CTSV/SMOC1/FERMT1/DPP4/CAV1 23 GO:0043588 skin development 21/580 263/18722 7.5841096180258e-05 0.00332770696541868 LAMA5/ITGB4/EGFR/CLDN4/ITGA6/LGR5/FRAS1/LGR4/PLEC/MET/ZFP36L1/DHCR24/LSR/FERMT1/ROCK1/DSP/NCOA3/SRSF6/PTGES3/TXNIP/STMN1 21 GO:0008016 regulation of heart contraction 18/580 206/18722 7.7847166412064e-05 0.00338380533628514 ATP2B1/AKAP9/GAA/DSG2/GJA5/ISL1/GJA1/ADRB1/SLC9A1/ADM/CALM1/DSC2/GSTO1/CAV1/DSP/CYP2J2/CALM2/YWHAE 18 GO:0045229 external encapsulating structure organization 23/580 304/18722 8.02244779303593e-05 0.00345485228568612 ADAMTSL4/COL14A1/LRP1/COL4A2/ADAMTS6/SPINT1/LAMB1/VWA1/FBLN1/CCDC80/DAG1/LAMC1/APP/ITGB1/SPINT2/SERPINH1/MMP15/ADAMTS1/CTSV/SMOC1/FERMT1/DPP4/CAV1 23 GO:0098656 anion transmembrane transport 20/580 245/18722 8.24654755788369e-05 0.00348919306686776 LRP2/SLC26A2/TCAF1/ITGB1/SLC3A2/GABRE/SLC1A5/SLC12A9/GJA1/SLC43A2/FOLR1/SLC9A1/SLC19A1/PCYOX1/SLC13A4/SLC16A12/SLC38A9/MFSD10/ARL6IP5/VDAC1 20 GO:0097421 liver regeneration 7/580 35/18722 8.34693126673262e-05 0.00348919306686776 EGFR/RPS16/GLI3/SRSF5/TYMS/PCNA/CSNK2B 7 GO:0071241 cellular response to inorganic substance 19/580 226/18722 8.35256561223246e-05 0.00348919306686776 JUN/FOS/EGFR/FOSB/JUND/HSPA5/CDH1/APP/SERPINF1/IQGAP1/NCSTN/ATRX/JUNB/FUS/HSD17B1/LGMN/TFAP2A/HNRNPD/CACYBP 19 GO:0001701 in utero embryonic development 26/580 367/18722 8.40227098450203e-05 0.00348919306686776 SPINT1/KRT19/ITGB1/SPINT2/ZFP36L1/BPTF/RBBP6/N4BP2L2/GLI3/YBX1/ADM/RTN4/TBX3/HECTD1/CITED2/NR2F2/JUNB/MGAT1/BMP7/KRT8/EIF2S2/HM13/SLC39A1/PHLDA2/IGF2/RRM2 26 GO:0016052 carbohydrate catabolic process 15/580 154/18722 9.03549468262176e-05 0.00366694045906155 GAPDH/GAA/LDHA/APP/ALDOA/ENO1/GUSB/MANBA/LRP5/NEU1/TPI1/PKM/AGL/HMGB1/PYGL 15 GO:0003151 outflow tract morphogenesis 10/580 74/18722 9.09864380115946e-05 0.00366694045906155 LRP2/NRP2/TGFBR3/GJA5/ISL1/FOLR1/TBX3/CITED2/NIPBL/BMP7 10 GO:0050714 positive regulation of protein secretion 14/580 137/18722 9.18577095816322e-05 0.00366694045906155 LRP1/EGFR/KCNN4/WLS/SOX4/MYH10/ISL1/GJA1/KIF5B/TCF7L2/PPIA/FRMD4A/DYNLL1/PHPT1 14 GO:0090090 negative regulation of canonical Wnt signaling pathway 14/580 137/18722 9.18577095816322e-05 0.00366694045906155 EGR1/ZNRF3/TLE4/ISL1/TPBG/GLI3/DDIT3/FERMT1/GPC3/TCF7L2/NOTUM/CTNND1/CAV1/SIAH2 14 GO:0010649 regulation of cell communication by electrical coupling 5/580 16/18722 9.22451158267471e-05 0.00366694045906155 GJA5/GJA1/CALM1/CAV1/CALM2 5 GO:0042176 regulation of protein catabolic process 27/580 391/18722 9.48655116832189e-05 0.0037391482613445 LRP2/LRP1/EGFR/CDH1/EEF1A1/UFL1/RPL23/MYCBP2/HSPA1A/CTSC/TMEM259/GJA1/CTSA/DDB1/ROCK1/HMGCR/GPC3/HECTD1/CD81/VGLL4/CAV1/PSMD1/MYLIP/TIMP3/EIF3H/ATRAID/GPX1 27 GO:0045931 positive regulation of mitotic cell cycle 13/580 121/18722 9.74108479428243e-05 0.00380720885531156 EGFR/APP/PPP1R10/ADAMTS1/PBX1/PKN2/BRD4/EIF4G1/LGMN/CCND3/CDK1/ANAPC11/RAB11A 13 GO:1903311 regulation of mRNA metabolic process 22/580 288/18722 9.90949217384871e-05 0.00384075400838086 SON/ZFP36L1/SF1/RBM25/TNRC6A/HNRNPA1/YBX1/ROCK1/NPM1/PUM1/RBM39/FUS/SRSF6/TRA2B/HSPA8/HNRNPC/HNRNPD/CIRBP/NCL/SRSF3/CARHSP1/SERBP1 22 GO:0030901 midbrain development 11/580 90/18722 0.000104112477611003 0.0039690748636785 HSPA5/WLS/CALM1/DLG5/CALM2/DYNLL1/RHOA/YWHAE/YWHAH/CDC42/YWHAQ 11 GO:0035304 regulation of protein dephosphorylation 11/580 90/18722 0.000104112477611003 0.0039690748636785 HSP90B1/SLC39A10/BOD1L1/PPP1R15A/ROCK1/CALM1/PPIA/GNAI2/CALM2/YWHAE/CSNK2B 11 GO:0071560 cellular response to transforming growth factor beta stimulus 20/580 250/18722 0.000108805833099833 0.00411427585160427 FBN1/FBN2/JUN/FOS/COL4A2/GLG1/HSPA5/PEG10/LTBP1/TGFBR3/ITGB5/HSPA1A/ZFP36L1/FOLR1/FERMT1/CITED2/CAV1/CDKN1C/ID1/HPGD 20 GO:0031100 animal organ regeneration 10/580 76/18722 0.000114382103152276 0.0042902513045261 EGFR/TGFBR3/RPS16/GLI3/ADM/SRSF5/TYMS/PCNA/CDK1/CSNK2B 10 GO:0060669 embryonic placenta morphogenesis 6/580 26/18722 0.000116815268073412 0.00434646249447551 SPINT1/SPINT2/ZFP36L1/ADM/BMP7/IGF2 6 GO:0007229 integrin-mediated signaling pathway 12/580 107/18722 0.000118666883772282 0.00438031489226098 LAMA5/ITGB4/ITGAV/ITGA6/ITGB1/ITGB5/PLPP3/ADAMTS1/DST/FERMT1/PTPRA/CDC42 12 GO:0007015 actin filament organization 29/580 441/18722 0.00012439494855083 0.00455559768275519 HSP90B1/RHOB/IQGAP2/KANK1/PLEC/MET/ALDOA/ITGB5/SPTAN1/SPTBN1/FAT1/SLC9A1/TACSTD2/DIAPH1/ROCK1/CFL1/TMSB4X/WASF2/TRIOBP/MSRB2/ACTG1/ID1/TPM4/PFN1/RASA1/RHOA/TPM3/STMN1/CDC42 29 GO:0055117 regulation of cardiac muscle contraction 10/580 77/18722 0.000127867689671281 0.00464517518915079 AKAP9/DSG2/GJA5/SLC9A1/CALM1/DSC2/GSTO1/CAV1/DSP/CALM2 10 GO:0034329 cell junction assembly 28/580 420/18722 0.00012883844321661 0.00464517518915079 LRP1/ITGB4/CLDN4/LAMC1/MACF1/CDH1/ITGA6/APP/PLEC/IQGAP1/GJA5/GJA1/LSR/DST/TPBG/SLC9A1/ROCK1/DLG5/PKN2/JAM3/MARVELD3/EIF4G1/PTPRA/CTNND1/CAV1/ACTG1/RHOA/CDC42 28 GO:2001233 regulation of apoptotic signaling pathway 25/580 356/18722 0.00013135546739737 0.00469949445280899 TPT1/ITGAV/ITGA6/P4HB/HSPA1A/ENO1/ERP29/CTSC/DDIT3/PDIA3/PHIP/PMAIP1/MAGED1/TCF7L2/SIAH1/PPIA/CAV1/MIF/XBP1/TIMP3/SIAH2/GNAI2/S100A9/GPX1/HMGB2 25 GO:0001763 morphogenesis of a branching structure 17/580 196/18722 0.000133610790033568 0.00470775594277367 LAMA5/SPINT1/DAG1/LGR4/MET/SPINT2/LRP5/PBX1/GLI3/ADM/TACSTD2/RTN4/TBX3/DLG5/MAGED1/GPC3/BMP7 17 GO:0031032 actomyosin structure organization 17/580 196/18722 0.000133610790033568 0.00470775594277367 KRT19/ITGB1/PLEC/MET/ITGB5/MYH10/SLC9A1/TACSTD2/ROCK1/WASF2/ACTG1/KRT8/PFN1/RHOA/STMN1/CDC42/CNN3 17 GO:0035637 multicellular organismal signaling 15/580 160/18722 0.000138984670727367 0.00479004127697796 ATP2B1/AKAP9/PLEC/DSG2/GJA5/ISL1/GJA1/SLC9A1/CALM1/JAM3/DSC2/CAV1/DSP/CALM2/YWHAE 15 GO:0045185 maintenance of protein location 11/580 93/18722 0.000140329919940679 0.00479004127697796 FBN1/FBN2/HSPA5/LTBP1/GPAA1/GJA1/OS9/CAV1/TMSB4X/TXN/NFKBIA 11 GO:0060993 kidney morphogenesis 11/580 93/18722 0.000140329919940679 0.00479004127697796 LAMA5/FRAS1/LGR4/SOX4/PBX1/GLI3/TACSTD2/IRX2/MAGED1/GPC3/BMP7 11 GO:0050878 regulation of body fluid levels 26/580 379/18722 0.000141307925476105 0.00479004127697796 F5/EGFR/FBLN1/CLDN4/KCNN4/LMAN1/PLEC/MET/ANXA5/GJA5/GJA1/LSR/ADM/GNAQ/PPIA/PRLR/COPA/CAV1/IL6ST/ACTG1/XBP1/GNAI2/TFPI2/STMN1/MYL12A/CYBA 26 GO:0051346 negative regulation of hydrolase activity 26/580 379/18722 0.000141307925476105 0.00479004127697796 GAPDH/LRP1/SPINT1/ITIH5/APLP2/CRIM1/APP/SERPINF1/BOD1L1/SPINT2/DHCR24/SERPINH1/PPP1R15A/ROCK1/POR/KDM5A/GPC3/TIMP3/SIAH2/GNAI2/GPX1/PRKCZ/SERPINB9/SERPINB1/TFPI2/CNN3 26 GO:0071248 cellular response to metal ion 17/580 197/18722 0.000142125499080404 0.00479004127697796 JUN/FOS/EGFR/FOSB/JUND/HSPA5/CDH1/APP/SERPINF1/IQGAP1/NCSTN/JUNB/FUS/HSD17B1/LGMN/TFAP2A/CACYBP 17 GO:0097242 amyloid-beta clearance 7/580 38/18722 0.000144541165494208 0.00483640978930618 LRP2/LRP1/LRPAP1/IGF1R/ROCK1/HMGCR/RAB11A 7 GO:0048857 neural nucleus development 9/580 64/18722 0.000148937446189852 0.00491414262890484 HSPA5/CALM1/CALM2/DYNLL1/RHOA/YWHAE/YWHAH/CDC42/YWHAQ 9 GO:0003205 cardiac chamber development 15/580 161/18722 0.000148985423603239 0.00491414262890484 LRP2/ADAMTS6/NRP2/TGFBR3/SOX4/GJA5/ISL1/ADAMTS1/TRIP11/LMO4/TBX3/HECTD1/CITED2/BMP7/DSP 15 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 20/580 256/18722 0.000150034025651362 0.00491414262890484 FBN1/FBN2/LRP2/LRP1/GLG1/HSPA5/PEG10/CRIM1/LTBP1/TGFBR3/HSPA1A/FOLR1/FERMT1/GPC3/CITED2/BMP7/CAV1/FSTL1/CDKN1C/CSNK2B 20 GO:1902414 protein localization to cell junction 11/580 94/18722 0.000154565940214849 0.00502717613943539 DAG1/LSR/DLG5/KIF5B/JAM3/MARVELD3/VAMP2/ACTG1/DSP/PRKCZ/RAB11A 11 GO:0060537 muscle tissue development 27/580 403/18722 0.000156075079523221 0.00504100829765627 LRP2/FOS/EGR1/TGFBR3/ITGB1/PLEC/GPC1/DSG2/GJA5/ISL1/GJA1/SLC9A1/HMGCR/TBX3/CITED2/NR2F2/CENPF/VGLL4/BMP7/CAV1/DSP/GPX1/RHOA/IGF2/CDK1/CDC42/CACYBP 27 GO:0070997 neuron death 25/580 361/18722 0.000163170326209369 0.00523382887723984 GAPDH/JUN/LRP1/FOS/GRN/HSPA5/EGR1/APP/SERPINF1/NCSTN/ISL1/TMEM259/DHCR24/SLC9A1/ERBB3/DDIT3/SIAH1/EIF4G1/LGMN/TFAP2A/ARL6IP5/RASA1/GPX1/RHOA/CDC42 25 GO:0048568 embryonic organ development 28/580 427/18722 0.000169813607732463 0.00540961020249099 FBN1/FBN2/SPINT1/EFEMP1/NAGLU/KRT19/SPINT2/ZFP36L1/BPTF/RBBP6/FOLR1/PBX1/GLI3/ADM/TBX3/HECTD1/CITED2/NR2F2/JUNB/NIPBL/BMP7/TRIOBP/KRT8/TFAP2A/TRA2B/SLC39A1/PHLDA2/IGF2 28 GO:0086091 regulation of heart rate by cardiac conduction 7/580 39/18722 0.000171502216040922 0.00542445360684045 AKAP9/DSG2/ISL1/DSC2/CAV1/DSP/YWHAE 7 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 13/580 128/18722 0.000172612155195095 0.00542445360684045 FBN1/FBN2/GLG1/HSPA5/PEG10/LTBP1/TGFBR3/HSPA1A/FOLR1/FERMT1/CITED2/CAV1/CDKN1C 13 GO:0061138 morphogenesis of a branching epithelium 16/580 182/18722 0.000178676530536241 0.00557734592969166 LAMA5/SPINT1/DAG1/LGR4/MET/SPINT2/LRP5/PBX1/GLI3/ADM/TACSTD2/TBX3/DLG5/MAGED1/GPC3/BMP7 16 GO:0032388 positive regulation of intracellular transport 17/580 202/18722 0.000192212683476956 0.00595987460567549 TCAF1/CDH1/DYNC1H1/B3GAT3/GLI3/KIF5B/TCF7L2/CD81/VAMP2/STOM/TPR/LEPROT/RAN/YWHAE/CDK1/CDC42/UBE2L3 17 GO:0001889 liver development 14/580 147/18722 0.000194924028668172 0.00596441879826098 EGFR/TGFBR3/RPS16/MET/LSR/GLI3/CITED2/ARID5B/XBP1/SRSF5/TYMS/HNRNPD/PCNA/CSNK2B 14 GO:0016331 morphogenesis of embryonic epithelium 14/580 147/18722 0.000194924028668172 0.00596441879826098 LRP2/LAMA5/SPINT1/SPINT2/SOX4/FOLR1/ADM/IRX2/LMO4/HECTD1/CITED2/BMP7/TFAP2A/PFN1 14 GO:0045740 positive regulation of DNA replication 7/580 40/18722 0.000202388048714344 0.00615233212137526 JUN/EGFR/ATRX/PCNA/CDK1/CDC42/CACYBP 7 GO:0010466 negative regulation of peptidase activity 20/580 262/18722 0.000204460117172578 0.00617496107123155 GAPDH/LRP1/SPINT1/ITIH5/APLP2/CRIM1/APP/SERPINF1/SPINT2/DHCR24/SERPINH1/ROCK1/POR/GPC3/TIMP3/SIAH2/GPX1/SERPINB9/SERPINB1/TFPI2 20 GO:1905897 regulation of response to endoplasmic reticulum stress 10/580 82/18722 0.000217174172320949 0.00644759113849394 HSPA5/UFL1/HSPA1A/ERP29/TMEM259/DDIT3/PPP1R15A/PMAIP1/CAV1/XBP1 10 GO:0046683 response to organophosphorus 13/580 131/18722 0.00021764605649184 0.00644759113849394 JUN/AKAP9/FOS/HSP90B1/FOSB/LDHA/HSPA5/APP/DUSP1/BSG/ZFP36L1/SLC6A4/TYMS 13 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 13/580 131/18722 0.00021764605649184 0.00644759113849394 FBN1/FBN2/GLG1/HSPA5/PEG10/LTBP1/TGFBR3/HSPA1A/FOLR1/FERMT1/CITED2/CAV1/CDKN1C 13 GO:0071692 protein localization to extracellular region 25/580 368/18722 0.00021918135864236 0.00645197784206087 FBN1/FBN2/LRP1/EGFR/LTBP1/KCNN4/WLS/SOX4/MYH10/ERP29/ISL1/LRP5/GJA1/DPP4/HMGCR/KIF5B/TCF7L2/PPIA/FRMD4A/PDIA4/HMGN3/CANX/DYNLL1/FAM3B/PHPT1 25 GO:0072659 protein localization to plasma membrane 21/580 284/18722 0.000221806471925751 0.00648646713810086 LAMA5/LRP1/EGFR/GOLGA4/MACF1/CDH1/ITGB1/BSG/SPTBN1/TPBG/ROCK1/KIF5B/HECTD1/CD81/TMEM150A/VAMP2/TMEM59/ARL6IP5/PRKCZ/MYL12A/RAB11A 21 GO:1903034 regulation of response to wounding 15/580 167/18722 0.000223142279530453 0.00648646713810086 LRP1/GRN/CLDN4/ITGB1/KANK1/PLPP3/GJA1/PTPRF/FERMT1/HMGCR/CAV1/ACTG1/XBP1/SRSF6/HMGB1 15 GO:0060348 bone development 17/580 205/18722 0.000229134192458964 0.00661927409395429 FBN1/GLG1/SLC38A10/SERPINH1/LRP5/GJA1/ATP6AP1/GLI3/TRIP11/POR/BBX/CITED2/NOTUM/WASF2/HSD17B1/TFAP2A/RHOA 17 GO:1901989 positive regulation of cell cycle phase transition 12/580 115/18722 0.000236019275955526 0.00675581400361403 EGFR/APP/PPP1R10/ADAMTS1/PBX1/NPM1/BRD4/EIF4G1/CCND3/CDK1/ANAPC11/RAB11A 12 GO:0010001 glial cell differentiation 18/580 225/18722 0.000236765788559253 0.00675581400361403 LRP1/ITGB4/EGFR/SPINT1/GRN/DAG1/APP/PLEC/SOX4/NCSTN/GPC1/ERBB3/GLI3/CDK6/IL6ST/S100A9/RHOA/CDK1 18 GO:0035581 sequestering of extracellular ligand from receptor 4/580 11/18722 0.000252878335859082 0.00717156792732066 FBN1/FBN2/LTBP1/CD46 4 GO:0050679 positive regulation of epithelial cell proliferation 17/580 207/18722 0.000257047165754259 0.00724561435104883 EGFR/LAMB1/NRP2/GRN/LAMC1/RTN4/TCF7L2/EMC10/XBP1/SRSF6/MYDGF/ID1/HMGB1/IGF2/HMGB2/CDC42/CYBA 17 GO:0045861 negative regulation of proteolysis 24/580 351/18722 0.000264641016338802 0.00741473112645645 GAPDH/LRP1/SPINT1/GLG1/ITIH5/APLP2/CRIM1/APP/SERPINF1/RPL23/SPINT2/DHCR24/SERPINH1/ROCK1/POR/GPC3/TMEM59/TIMP3/SIAH2/EIF3H/GPX1/SERPINB9/SERPINB1/TFPI2 24 GO:0045665 negative regulation of neuron differentiation 9/580 69/18722 0.00026723628467656 0.00744261053910588 APP/ISL1/PBX1/GLI3/SLC6A4/EIF2AK4/BMP7/ASPM/RHOA 9 GO:1902751 positive regulation of cell cycle G2/M phase transition 6/580 30/18722 0.000271165105615483 0.00750572631040052 APP/PBX1/NPM1/BRD4/CDK1/RAB11A 6 GO:0098900 regulation of action potential 8/580 55/18722 0.000272730111042289 0.00750572631040052 AKAP9/DSG2/GJA5/SLC9A1/CALM1/DSC2/CAV1/DSP 8 GO:0021915 neural tube development 14/580 152/18722 0.000276335819087344 0.00756022290926611 LRP2/SPINT1/SPINT2/SOX4/ZFP36L1/FOLR1/GLI3/ADM/LMO4/HECTD1/CITED2/ATP6AP2/BMP7/PFN1 14 GO:0045936 negative regulation of phosphate metabolic process 28/580 441/18722 0.000288101408093784 0.0078360213394397 LRP1/FBLN1/GADD45B/PLEC/BOD1L1/DUSP1/PLPP3/DUSP6/LRP5/PRKDC/PPP1R15A/GNAQ/ROCK1/HMGCR/CALM1/NPM1/NR2F2/PPIA/EIF4G1/BMP7/CAV1/CTDSPL/CDKN1C/GNAI2/CALM2/PRKCZ/DYNLL1/YWHAE 28 GO:0001656 metanephros development 10/580 85/18722 0.000292414664180651 0.00786139076938849 FBN1/EGR1/FRAS1/LGR4/GLI3/IRX2/DLG5/GPC3/NIPBL/BMP7 10 GO:0071277 cellular response to calcium ion 10/580 85/18722 0.000292414664180651 0.00786139076938849 FOS/FOSB/JUND/HSPA5/IQGAP1/NCSTN/JUNB/FUS/LGMN/CACYBP 10 GO:0010563 negative regulation of phosphorus metabolic process 28/580 442/18722 0.000298839022342128 0.00798088914255538 LRP1/FBLN1/GADD45B/PLEC/BOD1L1/DUSP1/PLPP3/DUSP6/LRP5/PRKDC/PPP1R15A/GNAQ/ROCK1/HMGCR/CALM1/NPM1/NR2F2/PPIA/EIF4G1/BMP7/CAV1/CTDSPL/CDKN1C/GNAI2/CALM2/PRKCZ/DYNLL1/YWHAE 28 GO:0006413 translational initiation 12/580 118/18722 0.000300291464189893 0.00798088914255538 RPL13A/RPS3A/RPS17/EIF3A/PPP1R15A/NPM1/EIF4G1/EIF2AK4/TPR/EIF2S2/EIF3H/EIF4B 12 GO:1990778 protein localization to cell periphery 23/580 333/18722 0.000305827500416613 0.00808183922975948 LAMA5/LRP1/EGFR/DAG1/GOLGA4/MACF1/CDH1/ITGB1/BSG/SPTBN1/TPBG/ROCK1/KIF5B/HECTD1/CD81/TMEM150A/VAMP2/CAV1/TMEM59/ARL6IP5/PRKCZ/MYL12A/RAB11A 23 GO:0001841 neural tube formation 11/580 102/18722 0.000319304818488693 0.00839032039994864 LRP2/SPINT1/SPINT2/SOX4/FOLR1/ADM/LMO4/HECTD1/CITED2/BMP7/PFN1 11 GO:0051099 positive regulation of binding 15/580 173/18722 0.000327263390926404 0.00851009589749177 LRP1/APP/MET/ISL1/CALM1/TCF7L2/EIF4G1/CAV1/TXN/CALM2/HMGB1/RAN/STMN1/HMGB2/GMNN 15 GO:0071711 basement membrane organization 6/580 31/18722 0.000327522503902607 0.00851009589749177 LAMB1/DAG1/ITGB1/SPINT2/FERMT1/CAV1 6 GO:0003281 ventricular septum development 9/580 71/18722 0.000332472776898933 0.00859072714087188 LRP2/TGFBR3/SOX4/GJA5/TRIP11/LMO4/TBX3/HECTD1/CITED2 9 GO:0050684 regulation of mRNA processing 13/580 137/18722 0.000338483569124429 0.00869771867402055 SON/ZFP36L1/SF1/RBM25/HNRNPA1/NPM1/RBM39/SRSF6/TRA2B/HSPA8/CIRBP/NCL/SRSF3 13 GO:0002027 regulation of heart rate 11/580 103/18722 0.000347692261936919 0.00888525664982752 AKAP9/DSG2/ISL1/ADRB1/ADM/CALM1/DSC2/CAV1/DSP/CALM2/YWHAE 11 GO:0051897 positive regulation of protein kinase B signaling 12/580 120/18722 0.000350920579170181 0.00891875198754377 LRP2/EGFR/ITGB1/MET/TPBG/IGF1R/RTN4/TCF7L2/TXN/MYDGF/GPX1/IGF2 12 GO:0032386 regulation of intracellular transport 23/580 337/18722 0.000362218129339395 0.00892099185136088 TCAF1/CDH1/DYNC1H1/LMAN1/B3GAT3/GLI3/FERMT1/GCC2/OS9/KIF5B/TCF7L2/CD81/NUCB1/VAMP2/STOM/TPR/TXN/LEPROT/RAN/YWHAE/CDK1/CDC42/UBE2L3 23 GO:1901654 response to ketone 16/580 194/18722 0.000368729209966618 0.00892099185136088 ATP2B1/FOS/EGFR/FOSB/CLDN4/TGFBR3/SERPINF1/DUSP1/CALM1/CAV1/TYMS/HNRNPD/TXNIP/PCNA/CSNK2B/CYBA 16 GO:0005977 glycogen metabolic process 9/580 72/18722 0.000369714879872473 0.00892099185136088 GAA/IL6ST/AGL/PHLDA2/PTGES3/HMGB1/IGF2/PYGL/UGP2 9 GO:0033627 cell adhesion mediated by integrin 9/580 72/18722 0.000369714879872473 0.00892099185136088 FBN1/ITGB4/ITGAV/ITGB1/ITGB5/PLPP3/FERMT1/DPP4/JAM3 9 GO:0030099 myeloid cell differentiation 25/580 381/18722 0.0003697234211435 0.00892099185136088 FBN1/JUN/FOS/CSF3R/APP/RPS6/TGFBR3/UFL1/HSPA1A/ZFP36L1/ESRRA/ATP6AP1/PRKDC/TFRC/GPC3/CITED2/CD81/JUNB/CDK6/WASF2/NFKBIA/HMGB1/DHRS2/HMGB2/CDC42 25 GO:0070493 thrombin-activated receptor signaling pathway 4/580 12/18722 0.000370046467760702 0.00892099185136088 IQGAP2/MET/HPGD/STMN1 4 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress 4/580 12/18722 0.000370046467760702 0.00892099185136088 JUN/HSPA1A/CITED2/DNAJB1 4 GO:0098911 regulation of ventricular cardiac muscle cell action potential 4/580 12/18722 0.000370046467760702 0.00892099185136088 DSG2/DSC2/CAV1/DSP 4 GO:1990034 calcium ion export across plasma membrane 4/580 12/18722 0.000370046467760702 0.00892099185136088 ATP2B1/CALM1/CALM2/YWHAE 4 GO:1905475 regulation of protein localization to membrane 15/580 175/18722 0.000370189513505192 0.00892099185136088 LRP1/EGFR/TCAF1/DAG1/ITGB1/GPC1/SPTBN1/KIF5B/GPC3/HECTD1/CD81/STOM/TMEM59/PRKCZ/RAB11A 15 GO:0062208 positive regulation of pattern recognition receptor signaling pathway 7/580 44/18722 0.000373783450350257 0.00896116921432496 HSPA1A/RTN4/PUM1/CAV1/NINJ1/HMGB1/CYBA 7 GO:0045056 transcytosis 5/580 21/18722 0.000377946640684357 0.00898947907764445 LRP2/LRP1/LRPAP1/IGF1R/RAB11A 5 GO:0001838 embryonic epithelial tube formation 12/580 121/18722 0.000378829907378695 0.00898947907764445 LRP2/SPINT1/SPINT2/SOX4/FOLR1/ADM/IRX2/LMO4/HECTD1/CITED2/BMP7/PFN1 12 GO:0010232 vascular transport 10/580 88/18722 0.000388295099678585 0.00916731222642181 LRP2/LRP1/SLC2A1/SLC38A2/SLC1A5/GJA1/SLC38A1/SLC19A1/TFRC/SLC16A12 10 GO:0043254 regulation of protein-containing complex assembly 27/580 427/18722 0.000392022557435979 0.00917706096064727 AKAP9/RPL13A/HSPA5/IQGAP2/CLIP1/KANK1/MET/HSPA1A/SPTAN1/SPTBN1/ISL1/FERMT1/LMO4/TFRC/JAM3/EIF4G1/TMSB4X/WASF2/TRIOBP/PFN1/RASA1/HSPA8/PRKCZ/RHOA/HMGB1/STMN1/CDC42 27 GO:0072337 modified amino acid transport 6/580 32/18722 0.000392654296101657 0.00917706096064727 LRP2/SLC38A2/GJA1/FOLR1/SLC19A1/SLC16A12 6 GO:0086065 cell communication involved in cardiac conduction 8/580 58/18722 0.000395846695086026 0.00920541489422554 DSG2/GJA5/GJA1/CALM1/DSC2/CAV1/DSP/CALM2 8 GO:1903829 positive regulation of cellular protein localization 20/580 276/18722 0.000403352298769471 0.00932156191329592 LRP1/EGFR/TCAF1/CDH1/ITGB1/IQGAP1/SPTBN1/GLI3/RTN4/KIF5B/TFRC/NPM1/CD81/STOM/TPR/LEPROT/RAN/CDK1/UBE2L3/RAB11A 20 GO:0006073 cellular glucan metabolic process 9/580 73/18722 0.000410329489905499 0.00932156191329592 GAA/IL6ST/AGL/PHLDA2/PTGES3/HMGB1/IGF2/PYGL/UGP2 9 GO:0044042 glucan metabolic process 9/580 73/18722 0.000410329489905499 0.00932156191329592 GAA/IL6ST/AGL/PHLDA2/PTGES3/HMGB1/IGF2/PYGL/UGP2 9 GO:0072089 stem cell proliferation 9/580 73/18722 0.000410329489905499 0.00932156191329592 FBLN1/RNF43/ZNRF3/ZFP36L1/GJA1/N4BP2L2/FERMT1/TBX3/HMGB2 9 GO:0032231 regulation of actin filament bundle assembly 11/580 105/18722 0.000410862221506271 0.00932156191329592 MET/SLC9A1/TACSTD2/ROCK1/WASF2/ACTG1/ID1/PFN1/RHOA/STMN1/CDC42 11 GO:0031667 response to nutrient levels 29/580 474/18722 0.00041575829179698 0.00938685347159105 JUN/ATP2B1/EGFR/LDHA/HSPA5/SLC2A1/PLEC/SLC38A2/ADRB1/TNRC6A/FOLR1/HNRNPA1/DDIT3/ADM/CTSV/HMGCR/POR/PMAIP1/CSH1/SLC6A4/EIF4G1/EIF2AK4/BMP7/XBP1/AGL/GNAI2/TYMS/HSPA8/CYBA 29 GO:0009612 response to mechanical stimulus 17/580 216/18722 0.000422380790589644 0.00946285781156796 JUN/FOS/EGFR/FOSB/JUND/DAG1/SLC2A1/PLEC/SLC38A2/GJA1/SLC9A1/TMEM150C/CITED2/NFKBIA/RHOA/TXNIP/CYBA 17 GO:0031647 regulation of protein stability 21/580 298/18722 0.000423193813116778 0.00946285781156796 GAPDH/GRN/AAK1/RPL23/SOX4/PLPP3/HSPA1A/CTSA/DDOST/PRKDC/GNAQ/RTN4/NPM1/CD81/SIAH1/CTNND1/MYLIP/CMTM6/PTGES3/PFN1/HSPA8 21 GO:0051180 vitamin transport 7/580 45/18722 0.000430969085624681 0.00950332143600415 LRP2/SLC2A1/SLC2A8/SLC52A1/FOLR1/SLC52A2/SLC19A1 7 GO:0071496 cellular response to external stimulus 22/580 320/18722 0.000437016338644878 0.00950332143600415 JUN/ATP2B1/FOS/EGFR/DAG1/HSPA5/SLC2A1/PLEC/SLC38A2/GJA1/TNRC6A/FOLR1/HNRNPA1/SLC9A1/CTSV/TMEM150C/PMAIP1/EIF4G1/EIF2AK4/XBP1/HSPA8/CYBA 22 GO:0010811 positive regulation of cell-substrate adhesion 12/580 123/18722 0.000440306014845668 0.00950332143600415 CCDC80/DAG1/ITGA6/P4HB/UTRN/IQGAP1/FERMT1/ROCK1/CDK6/TRIOBP/PRKCZ/CDC42 12 GO:0022898 regulation of transmembrane transporter activity 20/580 278/18722 0.000442420640630672 0.00950332143600415 AKAP9/AHNAK/TCAF1/APP/ITGB1/UTRN/GJA1/SLC9A1/CALM1/KIF5B/C4orf3/VAMP2/GSTO1/CAV1/STOM/TMSB4X/FXYD3/CALM2/YWHAE/YWHAH 20 GO:0009266 response to temperature stimulus 15/580 178/18722 0.000443609048488085 0.00950332143600415 ATP2B1/FOS/HSPA1A/ADRB1/SLC9A1/ADM/EIF2AK4/TPR/NR2F6/DNAJB1/ACADVL/NFKBIA/PLAC8/CIRBP/YWHAE 15 GO:0090303 positive regulation of wound healing 8/580 59/18722 0.000445712808937563 0.00950332143600415 CLDN4/ITGB1/KANK1/PLPP3/FERMT1/ACTG1/XBP1/HMGB1 8 GO:0030038 contractile actin filament bundle assembly 11/580 106/18722 0.000445889959659521 0.00950332143600415 MET/ITGB5/SLC9A1/TACSTD2/ROCK1/WASF2/ACTG1/PFN1/RHOA/STMN1/CDC42 11 GO:0043149 stress fiber assembly 11/580 106/18722 0.000445889959659521 0.00950332143600415 MET/ITGB5/SLC9A1/TACSTD2/ROCK1/WASF2/ACTG1/PFN1/RHOA/STMN1/CDC42 11 GO:0032355 response to estradiol 13/580 141/18722 0.000447479551598562 0.00950332143600415 EGFR/DUSP1/MMP15/GJA1/ESRRA/NR2F2/SLC6A4/BMP7/NCOA3/HNRNPD/HPGD/TXNIP/PCNA 13 GO:0035296 regulation of tube diameter 13/580 141/18722 0.000447479551598562 0.00950332143600415 ATP2B1/EGFR/SOD3/GJA5/GJA1/ADRB1/ADM/ROCK1/HMGCR/SLC6A4/CAV1/GPX1/RHOA 13 GO:0097746 blood vessel diameter maintenance 13/580 141/18722 0.000447479551598562 0.00950332143600415 ATP2B1/EGFR/SOD3/GJA5/GJA1/ADRB1/ADM/ROCK1/HMGCR/SLC6A4/CAV1/GPX1/RHOA 13 GO:0043542 endothelial cell migration 20/580 279/18722 0.00046316007442917 0.00979162502804578 NRP2/GRN/RHOB/ITGB1/SERPINF1/MET/PLPP3/EPHB4/DPP4/NR2F2/EMC10/TMSB4X/FSTL1/LGMN/ID1/GPX1/S100P/RHOA/HMGB1/CSNK2B 20 GO:0048048 embryonic eye morphogenesis 6/580 33/18722 0.00046747680272888 0.00979421823405009 FBN1/FBN2/EFEMP1/CITED2/BMP7/TFAP2A 6 GO:0052548 regulation of endopeptidase activity 27/580 432/18722 0.000469415414908627 0.00979421823405009 GAPDH/SPINT1/ITIH5/APLP2/CTSD/CRIM1/APP/SERPINF1/SPINT2/NCSTN/DHCR24/SERPINH1/ROCK1/POR/PMAIP1/ASPH/LGMN/TIMP3/SIAH2/S100A9/ARL6IP5/GPX1/RHOA/SERPINB9/HMGB1/SERPINB1/TFPI2 27 GO:0007163 establishment or maintenance of cell polarity 17/580 218/18722 0.000469600229239555 0.00979421823405009 RHOB/ITGB1/KANK1/SPINT2/GJA1/FAT1/DST/SLC9A1/FERMT1/ROCK1/DLG5/JAM3/FRMD4A/PRKCZ/RHOA/CDC42/DYNLT1 17 GO:0032069 regulation of nuclease activity 5/580 22/18722 0.000476733512618033 0.00985461140971766 HSPA1A/NPM1/HMGB1/PCNA/HMGB2 5 GO:0060713 labyrinthine layer morphogenesis 5/580 22/18722 0.000476733512618033 0.00985461140971766 SPINT1/SPINT2/ZFP36L1/ADM/BMP7 5 GO:0035150 regulation of tube size 13/580 142/18722 0.000478960787312152 0.00985684345924255 ATP2B1/EGFR/SOD3/GJA5/GJA1/ADRB1/ADM/ROCK1/HMGCR/SLC6A4/CAV1/GPX1/RHOA 13 GO:0031102 neuron projection regeneration 8/580 60/18722 0.000500557590339265 0.0102526915600486 LRP1/GRN/DAG1/ISL1/PTPRF/FOLR1/ADM/JAM3 8 GO:0061333 renal tubule morphogenesis 9/580 75/18722 0.000502604531432184 0.0102526915600486 LAMA5/LGR5/LGR4/PBX1/GLI3/TACSTD2/IRX2/MAGED1/GPC3 9 GO:0051271 negative regulation of cellular component movement 24/580 367/18722 0.000504819025529564 0.0102528964530044 LRP1/TCAF1/FBLN1/DAG1/RHOB/CDH1/ADGRG1/SEMA6D/TGFBR3/SERPINF1/KANK1/SPINT2/DUSP1/GJA1/TACSTD2/DPP4/DLG5/CITED2/NR2F2/MARVELD3/MIF/RHOA/HMGB1/CSNK2B 24 GO:0051492 regulation of stress fiber assembly 10/580 91/18722 0.000509009977797683 0.0102930669858131 MET/SLC9A1/TACSTD2/ROCK1/WASF2/ACTG1/PFN1/RHOA/STMN1/CDC42 10 GO:0034446 substrate adhesion-dependent cell spreading 11/580 108/18722 0.000523479742473356 0.0105398453776778 LAMA5/LAMB1/FBLN1/LAMC1/ITGAV/P4HB/KANK1/TACSTD2/TRIOBP/RHOA/CDC42 11 GO:0006936 muscle contraction 23/580 347/18722 0.00054482441432786 0.0108867509853688 ATP2B1/AKAP9/GAA/UTRN/ALDOA/ENO1/DSG2/GJA5/GJA1/SLC9A1/PABPN1/ROCK1/CALM1/TBX3/DSC2/GSTO1/CAV1/ASPH/DSP/TPM4/CALM2/RHOA/TPM3 23 GO:0002183 cytoplasmic translational initiation 6/580 34/18722 0.000552952063862664 0.0108867509853688 RPL13A/EIF3A/EIF4G1/EIF2S2/EIF3H/EIF4B 6 GO:0051085 chaperone cofactor-dependent protein refolding 6/580 34/18722 0.000552952063862664 0.0108867509853688 HSPA5/HSPA1A/DNAJB14/DNAJB1/PTGES3/HSPA8 6 GO:0086004 regulation of cardiac muscle cell contraction 6/580 34/18722 0.000552952063862664 0.0108867509853688 AKAP9/DSG2/GJA5/DSC2/CAV1/DSP 6 GO:0072028 nephron morphogenesis 9/580 76/18722 0.000554753812842917 0.0108867509853688 LAMA5/LGR4/PBX1/GLI3/TACSTD2/IRX2/MAGED1/GPC3/BMP7 9 GO:0086001 cardiac muscle cell action potential 9/580 76/18722 0.000554753812842917 0.0108867509853688 AKAP9/DSG2/GJA5/GJA1/CALM1/DSC2/CAV1/DSP/YWHAE 9 GO:0034113 heterotypic cell-cell adhesion 8/580 61/18722 0.000560742979408979 0.0109531683204021 ITGAV/ITGB1/DSG2/JAM3/DSC2/BMP7/DSP/NINJ1 8 GO:0071322 cellular response to carbohydrate stimulus 14/580 163/18722 0.000562848253832744 0.0109531683204021 LRP1/SERPINF1/SOX4/ZFP36L1/LRP5/IGF1R/HMGCR/KIF5B/HMGN3/XBP1/TRA2B/DYNLL1/PHPT1/CYBA 14 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 7/580 47/18722 0.000566224445389758 0.010972957897949 JUN/HSPA5/EGR1/HSPA1A/DDIT3/CITED2/DNAJB1 7 GO:0007517 muscle organ development 22/580 327/18722 0.000585010317030629 0.0112899708900807 LRP2/LAMA5/FOS/DAG1/EGR1/TGFBR3/UTRN/PLEC/GPC1/ISL1/ZFHX3/HMGCR/CITED2/NR2F2/CENPF/CAV1/ARID5B/DSP/XBP1/GPX1/RHOA/IGF2 22 GO:2001242 regulation of intrinsic apoptotic signaling pathway 14/580 164/18722 0.000598316640534183 0.0114990524591921 TPT1/P4HB/HSPA1A/ENO1/ERP29/DDIT3/PMAIP1/SIAH1/PPIA/CAV1/MIF/XBP1/S100A9/GPX1 14 GO:0051591 response to cAMP 10/580 93/18722 0.000605598028164383 0.0115435919221006 JUN/AKAP9/FOS/FOSB/LDHA/HSPA5/APP/DUSP1/BSG/ZFP36L1 10 GO:1901992 positive regulation of mitotic cell cycle phase transition 10/580 93/18722 0.000605598028164383 0.0115435919221006 EGFR/APP/ADAMTS1/PBX1/BRD4/EIF4G1/CCND3/CDK1/ANAPC11/RAB11A 10 GO:0007492 endoderm development 9/580 77/18722 0.000611253446792107 0.0116038358409391 COL4A2/LAMB1/LAMC1/ITGAV/DUSP1/ITGB5/ZFP36L1/MMP15/BPTF 9 GO:0007043 cell-cell junction assembly 13/580 146/18722 0.000624332164553233 0.0117576893902215 CLDN4/GJA5/GJA1/LSR/ROCK1/DLG5/PKN2/JAM3/MARVELD3/CTNND1/CAV1/ACTG1/RHOA 13 GO:0001666 response to hypoxia 21/580 307/18722 0.000624413949555946 0.0117576893902215 MALAT1/HSP90B1/LDHA/EGR1/P4HB/SOD3/TGFBR3/SLC2A1/ENO1/ZFP36L1/SLC2A8/SLC9A1/ADM/DPP4/PMAIP1/CITED2/SLC6A4/BMP7/CAV1/RHOA/CYBA 21 GO:0046661 male sex differentiation 14/580 165/18722 0.000635663716720351 0.0119212578486547 LRP2/ADGRG1/LGR4/DHCR24/SF1/CTSV/ATRX/TBX3/KDM5A/CITED2/ASPM/ARID5B/EIF2S2/HMGB2 14 GO:0001893 maternal placenta development 6/580 35/18722 0.00065008642617894 0.0120460237775229 BSG/GJA1/CTSV/CITED2/NR2F2/JUNB 6 GO:0035633 maintenance of blood-brain barrier 6/580 35/18722 0.00065008642617894 0.0120460237775229 LAMC1/ITGB1/GJA1/LSR/JAM3/ACTG1 6 GO:0045907 positive regulation of vasoconstriction 6/580 35/18722 0.00065008642617894 0.0120460237775229 EGFR/GJA5/GJA1/HMGCR/CAV1/RHOA 6 GO:0014020 primary neural tube formation 10/580 94/18722 0.000659292324348851 0.0121463239920145 LRP2/SPINT1/SPINT2/FOLR1/ADM/LMO4/HECTD1/CITED2/BMP7/PFN1 10 GO:0048638 regulation of developmental growth 22/580 330/18722 0.000660722418830287 0.0121463239920145 LRP1/GOLGA4/MACF1/SEMA6A/APP/SEMA6D/TGFBR3/DUSP6/GJA1/ADRB1/PRKDC/RTN4/DUSP9/CITED2/VGLL4/SLC6A4/NIPBL/LGMN/PLAC8/IGF2/CDK1/RAB11A 22 GO:0007369 gastrulation 15/580 185/18722 0.000664839794308222 0.0121738971784549 ITGB4/COL4A2/LAMB1/DAG1/ITGAV/RPS6/ITGB1/DUSP1/WLS/ITGB5/MMP15/LRP5/GJA1/GPC3/BMP7 15 GO:0022604 regulation of cell morphogenesis 21/580 309/18722 0.000678997594739669 0.0123843835809184 FBLN1/DAG1/RHOB/CLDN4/MACF1/P4HB/KANK1/ALDOA/MYH10/PRKDC/TACSTD2/DIAPH1/PHIP/CUX1/CFL1/TRIOBP/MYL12B/RASA1/RHOA/CDC42/MYL12A 21 GO:0032412 regulation of ion transmembrane transporter activity 19/580 267/18722 0.000695402218754448 0.0126340457790115 AKAP9/AHNAK/TCAF1/APP/ITGB1/UTRN/SLC9A1/CALM1/KIF5B/C4orf3/VAMP2/GSTO1/CAV1/STOM/TMSB4X/FXYD3/CALM2/YWHAE/YWHAH 19 GO:0035437 maintenance of protein localization in endoplasmic reticulum 4/580 14/18722 0.000712240149093205 0.0128896067448735 HSPA5/GPAA1/GJA1/OS9 4 GO:0006942 regulation of striated muscle contraction 10/580 95/18722 0.000716854937522517 0.0129228384279737 AKAP9/DSG2/GJA5/SLC9A1/CALM1/DSC2/GSTO1/CAV1/DSP/CALM2 10 GO:0050708 regulation of protein secretion 19/580 268/18722 0.000727441456240214 0.0130630510153407 LRP1/EGFR/KCNN4/WLS/SOX4/MYH10/ERP29/ISL1/LRP5/GJA1/DPP4/HMGCR/KIF5B/TCF7L2/PPIA/FRMD4A/HMGN3/DYNLL1/PHPT1 19 GO:0070849 response to epidermal growth factor 7/580 49/18722 0.000733208095294571 0.0130657120736209 EGFR/EEF1A1/IQGAP1/ZFP36L1/TPR/ID1/NCL 7 GO:0072091 regulation of stem cell proliferation 7/580 49/18722 0.000733208095294571 0.0130657120736209 FBLN1/ZFP36L1/GJA1/N4BP2L2/FERMT1/TBX3/HMGB2 7 GO:0071826 ribonucleoprotein complex subunit organization 17/580 227/18722 0.000742665101362248 0.0131837228489917 RPL13A/RPLP0/RPL23A/RPL6/SF1/EIF3A/PRKDC/KIF5B/SCAF11/LUC7L3/SRSF6/SRSF5/EIF2S2/PTGES3/EIF3H/SNRPD2/EIF4B 17 GO:1905039 carboxylic acid transmembrane transport 13/580 149/18722 0.000756365285400393 0.0133758743056929 LRP2/ITGB1/SLC3A2/SLC2A1/SLC38A2/SLC38A10/SLC1A5/SLC43A2/FOLR1/SLC38A1/SLC19A1/SLC38A9/ARL6IP5 13 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 12/580 131/18722 0.000777062070579225 0.0136898321600908 FBN1/FBN2/LRP2/LRP1/GLG1/HSPA5/PEG10/CRIM1/LTBP1/TGFBR3/HSPA1A/CAV1 12 GO:0032956 regulation of actin cytoskeleton organization 23/580 357/18722 0.00080310414062907 0.0140276517782885 LRP1/RHOB/IQGAP2/KANK1/MET/IQGAP1/SPTAN1/SPTBN1/SLC9A1/TACSTD2/ROCK1/JAM3/TMSB4X/WASF2/TRIOBP/ACTG1/ID1/PFN1/RASA1/RHOA/STMN1/CDC42/PHPT1 23 GO:1904062 regulation of cation transmembrane transport 23/580 357/18722 0.00080310414062907 0.0140276517782885 AKAP9/AHNAK/APP/KCNN4/ITGB1/UTRN/SLC43A2/SLC9A1/DIAPH1/CALM1/KIF5B/C4orf3/VAMP2/GSTO1/CAV1/STOM/TMSB4X/FXYD3/CALM2/VDAC1/YWHAE/YWHAH/CYBA 23 GO:1903825 organic acid transmembrane transport 13/580 150/18722 0.000805285535326389 0.0140276517782885 LRP2/ITGB1/SLC3A2/SLC2A1/SLC38A2/SLC38A10/SLC1A5/SLC43A2/FOLR1/SLC38A1/SLC19A1/SLC38A9/ARL6IP5 13 GO:0021987 cerebral cortex development 11/580 114/18722 0.000826838508628797 0.0143198178380543 LRP1/LAMB1/ADGRG1/SLC2A1/SLC38A2/GLI3/RTN4/TACC2/ASPM/TRA2B/RHOA 11 GO:0045667 regulation of osteoblast differentiation 12/580 132/18722 0.000831294520807279 0.0143198178380543 FBN2/JUND/CRIM1/LRP5/ESRRA/ATP6AP1/GLI3/SMOC1/CDK6/BMP7/IL6ST/ATRAID 12 GO:0072175 epithelial tube formation 12/580 132/18722 0.000831294520807279 0.0143198178380543 LRP2/SPINT1/SPINT2/SOX4/FOLR1/ADM/IRX2/LMO4/HECTD1/CITED2/BMP7/PFN1 12 GO:0048592 eye morphogenesis 13/580 151/18722 0.000856836321217119 0.0145976034065232 FBN1/FBN2/TENM3/EFEMP1/NAGLU/LRP5/FAT1/GLI3/CITED2/NIPBL/BMP7/TUG1/TFAP2A 13 GO:0048754 branching morphogenesis of an epithelial tube 13/580 151/18722 0.000856836321217119 0.0145976034065232 LAMA5/DAG1/LGR4/MET/LRP5/PBX1/GLI3/TACSTD2/TBX3/DLG5/MAGED1/GPC3/BMP7 13 GO:0071333 cellular response to glucose stimulus 13/580 151/18722 0.000856836321217119 0.0145976034065232 LRP1/SERPINF1/SOX4/LRP5/IGF1R/HMGCR/KIF5B/HMGN3/XBP1/TRA2B/DYNLL1/PHPT1/CYBA 13 GO:2000146 negative regulation of cell motility 23/580 359/18722 0.000865900695448312 0.0146914036115678 LRP1/TCAF1/FBLN1/DAG1/RHOB/CDH1/ADGRG1/SEMA6D/SERPINF1/KANK1/SPINT2/DUSP1/GJA1/TACSTD2/DPP4/DLG5/CITED2/NR2F2/MARVELD3/MIF/RHOA/HMGB1/CSNK2B 23 GO:0003161 cardiac conduction system development 6/580 37/18722 0.000883569617230591 0.0146914036115678 DSG2/GJA5/ISL1/GJA1/TBX3/CDC42 6 GO:0032570 response to progesterone 6/580 37/18722 0.000883569617230591 0.0146914036115678 FOS/FOSB/CLDN4/CAV1/TYMS/TXNIP 6 GO:1902903 regulation of supramolecular fiber organization 24/580 382/18722 0.000885165018114427 0.0146914036115678 AKAP9/IQGAP2/APP/CLIP1/KANK1/MET/HSPA1A/SPTAN1/SPTBN1/SLC9A1/TACSTD2/ROCK1/TMSB4X/WASF2/TRIOBP/ACTG1/ID1/PFN1/RASA1/HSPA8/GPX1/RHOA/STMN1/CDC42 24 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 9/580 81/18722 0.000886295179862902 0.0146914036115678 FBN1/FBN2/GLG1/HSPA5/PEG10/LTBP1/TGFBR3/HSPA1A/CAV1 9 GO:0071260 cellular response to mechanical stimulus 9/580 81/18722 0.000886295179862902 0.0146914036115678 EGFR/DAG1/SLC2A1/PLEC/SLC38A2/GJA1/SLC9A1/TMEM150C/CYBA 9 GO:0060706 cell differentiation involved in embryonic placenta development 5/580 25/18722 0.000890770977953586 0.0146914036115678 KRT19/SPINT2/HECTD1/NR2F2/KRT8 5 GO:0061436 establishment of skin barrier 5/580 25/18722 0.000890770977953586 0.0146914036115678 CLDN4/PLEC/MET/LSR/STMN1 5 GO:0086064 cell communication by electrical coupling involved in cardiac conduction 5/580 25/18722 0.000890770977953586 0.0146914036115678 GJA5/GJA1/CALM1/CAV1/CALM2 5 GO:0010951 negative regulation of endopeptidase activity 18/580 252/18722 0.000911655616479831 0.0149827218100625 GAPDH/SPINT1/ITIH5/APLP2/CRIM1/APP/SERPINF1/SPINT2/DHCR24/SERPINH1/ROCK1/POR/TIMP3/SIAH2/GPX1/SERPINB9/SERPINB1/TFPI2 18 GO:0010959 regulation of metal ion transport 25/580 406/18722 0.000928427088960069 0.0151185663549932 ATP2B1/AKAP9/AHNAK/KCNN4/ITGB1/UTRN/GJA1/SLC9A1/DIAPH1/CALM1/KIF5B/C4orf3/VAMP2/GSTO1/CAV1/STOM/PRSS8/GNAI2/FXYD3/CALM2/RHOA/VDAC1/YWHAE/YWHAH/CYBA 25 GO:0086069 bundle of His cell to Purkinje myocyte communication 4/580 15/18722 0.000947573893389113 0.0151185663549932 DSG2/GJA5/DSC2/DSP 4 GO:0098760 response to interleukin-7 4/580 15/18722 0.000947573893389113 0.0151185663549932 P4HB/YBX1/PDIA3/HMGB1 4 GO:0098761 cellular response to interleukin-7 4/580 15/18722 0.000947573893389113 0.0151185663549932 P4HB/YBX1/PDIA3/HMGB1 4 GO:1901660 calcium ion export 4/580 15/18722 0.000947573893389113 0.0151185663549932 ATP2B1/CALM1/CALM2/YWHAE 4 GO:0001508 action potential 12/580 134/18722 0.000949265363303689 0.0151185663549932 AKAP9/DSG2/GJA5/GJA1/SLC9A1/GNAQ/CALM1/DSC2/CAV1/DSP/YWHAE/YWHAH 12 GO:0061041 regulation of wound healing 12/580 134/18722 0.000949265363303689 0.0151185663549932 CLDN4/ITGB1/KANK1/PLPP3/GJA1/FERMT1/HMGCR/CAV1/ACTG1/XBP1/SRSF6/HMGB1 12 GO:0019229 regulation of vasoconstriction 8/580 66/18722 0.000955516165306076 0.0151185663549932 ATP2B1/EGFR/GJA5/GJA1/ADM/HMGCR/CAV1/RHOA 8 GO:0051893 regulation of focal adhesion assembly 8/580 66/18722 0.000955516165306076 0.0151185663549932 LRP1/MACF1/IQGAP1/SLC9A1/ROCK1/PTPRA/ACTG1/RHOA 8 GO:0090109 regulation of cell-substrate junction assembly 8/580 66/18722 0.000955516165306076 0.0151185663549932 LRP1/MACF1/IQGAP1/SLC9A1/ROCK1/PTPRA/ACTG1/RHOA 8 GO:0021782 glial cell development 11/580 116/18722 0.000955678028030101 0.0151185663549932 LRP1/ITGB4/EGFR/GRN/DAG1/APP/PLEC/SOX4/NCSTN/CDK6/S100A9 11 GO:0071331 cellular response to hexose stimulus 13/580 153/18722 0.000968272925187784 0.0152658894069437 LRP1/SERPINF1/SOX4/LRP5/IGF1R/HMGCR/KIF5B/HMGN3/XBP1/TRA2B/DYNLL1/PHPT1/CYBA 13 GO:0042326 negative regulation of phosphorylation 24/580 385/18722 0.00098566069743926 0.0154875267019932 LRP1/FBLN1/GADD45B/PLEC/DUSP1/PLPP3/DUSP6/LRP5/PRKDC/GNAQ/ROCK1/HMGCR/CALM1/NPM1/NR2F2/PPIA/EIF4G1/BMP7/CAV1/CTDSPL/CDKN1C/CALM2/PRKCZ/DYNLL1 24 GO:0000910 cytokinesis 14/580 173/18722 0.00101203604523399 0.0158484163177888 SON/RHOB/PLEC/MYH10/SPTBN1/ROCK1/CALM1/PKN2/RASA1/CALM2/RHOA/STMN1/CDC42/RAB11A 14 GO:0071326 cellular response to monosaccharide stimulus 13/580 154/18722 0.00102838811754499 0.0160504467607442 LRP1/SERPINF1/SOX4/LRP5/IGF1R/HMGCR/KIF5B/HMGN3/XBP1/TRA2B/DYNLL1/PHPT1/CYBA 13 GO:0007548 sex differentiation 19/580 276/18722 0.00103272994108417 0.0160643042006103 LRP2/HSPA5/ADGRG1/LGR4/DHCR24/SF1/ADAMTS1/PBX1/CTSV/ATRX/TBX3/KDM5A/CITED2/NR2F2/NIPBL/ASPM/ARID5B/EIF2S2/HMGB2 19 GO:0031103 axon regeneration 7/580 52/18722 0.00105422331079031 0.0161813580244981 LRP1/GRN/DAG1/ISL1/PTPRF/FOLR1/JAM3 7 GO:0001933 negative regulation of protein phosphorylation 22/580 342/18722 0.00105500443723063 0.0161813580244981 LRP1/FBLN1/GADD45B/PLEC/DUSP1/PLPP3/DUSP6/LRP5/PRKDC/GNAQ/HMGCR/CALM1/NPM1/NR2F2/PPIA/EIF4G1/BMP7/CAV1/CTDSPL/CDKN1C/CALM2/PRKCZ 22 GO:0009314 response to radiation 27/580 456/18722 0.00105869561972184 0.0161813580244981 JUN/FOS/EGFR/JUND/RHOB/HSPA5/EGR1/APP/ITGB1/DUSP1/TP53I13/LRP5/DDB1/PRKDC/GNAQ/HMGCR/NPM1/NIPBL/EIF2AK4/TXN/NR2F6/ADIRF/GPX1/CIRBP/DYNLRB1/PCNA/CYBA 27 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 21/580 320/18722 0.0010591680805621 0.0161813580244981 SON/SF1/RBM25/HNRNPA1/NPM1/SCAF11/RBM39/LUC7L3/SRRM2/SRSF6/SRSF5/TRA2B/PNN/HSPA8/SNRPD2/HNRNPC/CIRBP/HNRNPA2B1/HNRNPA3/NCL/SRSF3 21 GO:0000398 mRNA splicing, via spliceosome 21/580 320/18722 0.0010591680805621 0.0161813580244981 SON/SF1/RBM25/HNRNPA1/NPM1/SCAF11/RBM39/LUC7L3/SRRM2/SRSF6/SRSF5/TRA2B/PNN/HSPA8/SNRPD2/HNRNPC/CIRBP/HNRNPA2B1/HNRNPA3/NCL/SRSF3 21 GO:0001659 temperature homeostasis 14/580 174/18722 0.00107012534013997 0.0161813580244981 EGR1/DYNC1H1/LGR4/GJA1/ADRB1/DDIT3/IGF1R/PRLR/CAV1/ID1/ACADVL/GADD45G/GPX1/PLAC8 14 GO:0060840 artery development 10/580 100/18722 0.00107028615691954 0.0161813580244981 LRP2/LRP1/ADAMTS6/SOX4/GJA5/FOLR1/GLI3/HECTD1/CITED2/HPGD 10 GO:0110020 regulation of actomyosin structure organization 10/580 100/18722 0.00107028615691954 0.0161813580244981 MET/SLC9A1/TACSTD2/ROCK1/WASF2/ACTG1/PFN1/RHOA/STMN1/CDC42 10 GO:0002026 regulation of the force of heart contraction 5/580 26/18722 0.00107504614697267 0.0161813580244981 GAA/ADRB1/SLC9A1/ADM/CAV1 5 GO:0046697 decidualization 5/580 26/18722 0.00107504614697267 0.0161813580244981 BSG/GJA1/CTSV/CITED2/JUNB 5 GO:0003158 endothelium development 12/580 136/18722 0.00108085225402404 0.0162162704305348 RHOB/MET/GJA5/GJA1/BTG1/ROCK1/NR2F2/FSTL1/ID1/GPX1/RHOA/CSNK2B 12 GO:0048738 cardiac muscle tissue development 17/580 236/18722 0.00114154067027562 0.0169088386509989 LRP2/TGFBR3/ITGB1/PLEC/DSG2/GJA5/ISL1/GJA1/SLC9A1/TBX3/CITED2/VGLL4/BMP7/DSP/CDK1/CDC42/CACYBP 17 GO:0036293 response to decreased oxygen levels 21/580 322/18722 0.00114506120110608 0.0169088386509989 MALAT1/HSP90B1/LDHA/EGR1/P4HB/SOD3/TGFBR3/SLC2A1/ENO1/ZFP36L1/SLC2A8/SLC9A1/ADM/DPP4/PMAIP1/CITED2/SLC6A4/BMP7/CAV1/RHOA/CYBA 21 GO:0007266 Rho protein signal transduction 12/580 137/18722 0.0011521196477744 0.0169088386509989 RHOB/ADGRG1/ITGB1/KANK1/MET/ROCK1/HACD3/CFL1/RHOA/STMN1/CDC42/CTNNAL1 12 GO:0060048 cardiac muscle contraction 12/580 137/18722 0.0011521196477744 0.0169088386509989 AKAP9/GAA/DSG2/GJA5/GJA1/SLC9A1/CALM1/DSC2/GSTO1/CAV1/DSP/CALM2 12 GO:0006112 energy reserve metabolic process 9/580 84/18722 0.00115246223443703 0.0169088386509989 GAA/IL6ST/AGL/PHLDA2/PTGES3/HMGB1/IGF2/PYGL/UGP2 9 GO:0010921 regulation of phosphatase activity 9/580 84/18722 0.00115246223443703 0.0169088386509989 HSP90B1/SLC39A10/BOD1L1/PPP1R15A/ROCK1/CALM1/GNAI2/CALM2/CSNK2B 9 GO:0042310 vasoconstriction 9/580 84/18722 0.00115246223443703 0.0169088386509989 ATP2B1/EGFR/GJA5/GJA1/ADM/HMGCR/SLC6A4/CAV1/RHOA 9 GO:0060411 cardiac septum morphogenesis 8/580 68/18722 0.00116518205492021 0.0170417035768361 LRP2/NRP2/TGFBR3/SOX4/ISL1/TBX3/CITED2/BMP7 8 GO:0051084 'de novo' posttranslational protein folding 6/580 39/18722 0.00117679840391121 0.017104029301847 HSPA5/HSPA1A/DNAJB14/DNAJB1/PTGES3/HSPA8 6 GO:1903115 regulation of actin filament-based movement 6/580 39/18722 0.00117679840391121 0.017104029301847 AKAP9/DSG2/GJA5/DSC2/CAV1/DSP 6 GO:0043620 regulation of DNA-templated transcription in response to stress 7/580 53/18722 0.00118275361533473 0.017110968695517 JUN/HSPA5/EGR1/HSPA1A/DDIT3/CITED2/DNAJB1 7 GO:0006913 nucleocytoplasmic transport 20/580 301/18722 0.0011883128120086 0.017110968695517 CDH1/RPL23/PPP1R10/HNRNPA1/GLI3/PABPN1/FERMT1/NPM1/TCF7L2/NEMF/THOC2/TPR/TXN/NFKBIA/HNRNPA2B1/RAN/YWHAE/TXNIP/SRSF3/CDK1 20 GO:0051169 nuclear transport 20/580 301/18722 0.0011883128120086 0.017110968695517 CDH1/RPL23/PPP1R10/HNRNPA1/GLI3/PABPN1/FERMT1/NPM1/TCF7L2/NEMF/THOC2/TPR/TXN/NFKBIA/HNRNPA2B1/RAN/YWHAE/TXNIP/SRSF3/CDK1 20 GO:0040013 negative regulation of locomotion 24/580 391/18722 0.00121660517117395 0.0173208788307158 LRP1/TCAF1/FBLN1/DAG1/RHOB/SEMA6A/CDH1/ADGRG1/SEMA6D/SERPINF1/KANK1/SPINT2/DUSP1/GJA1/TACSTD2/DPP4/DLG5/CITED2/NR2F2/MARVELD3/MIF/RHOA/HMGB1/CSNK2B 24 GO:0035107 appendage morphogenesis 12/580 138/18722 0.00122724055290288 0.0173208788307158 FBN2/FRAS1/SOX4/LRP5/PBX1/GLI3/ATRX/TBX3/GPC3/NIPBL/BMP7/TFAP2A 12 GO:0035108 limb morphogenesis 12/580 138/18722 0.00122724055290288 0.0173208788307158 FBN2/FRAS1/SOX4/LRP5/PBX1/GLI3/ATRX/TBX3/GPC3/NIPBL/BMP7/TFAP2A 12 GO:0002262 myeloid cell homeostasis 13/580 157/18722 0.00122776252561396 0.0173208788307158 RPS6/TGFBR3/UFL1/NCSTN/HSPA1A/RPS17/ZFP36L1/PRKDC/CITED2/JAM3/CDK6/HMGB1/HMGB2 13 GO:0007030 Golgi organization 13/580 157/18722 0.00122776252561396 0.0173208788307158 AKAP9/GOLGB1/LMAN1/TRIP11/GCC2/TMED9/TMED1/ARHGAP21/TMED4/SURF4/LMAN2/CDK1/CDC42 13 GO:0051017 actin filament bundle assembly 13/580 157/18722 0.00122776252561396 0.0173208788307158 HSP90B1/MET/ITGB5/SLC9A1/TACSTD2/ROCK1/WASF2/ACTG1/ID1/PFN1/RHOA/STMN1/CDC42 13 GO:0005980 glycogen catabolic process 4/580 16/18722 0.0012326834859099 0.0173208788307158 GAA/AGL/HMGB1/PYGL 4 GO:0099010 modification of postsynaptic structure 4/580 16/18722 0.0012326834859099 0.0173208788307158 MYH10/PFN1/RHOA/CDC42 4 GO:0000375 RNA splicing, via transesterification reactions 21/580 324/18722 0.0012368643900472 0.017327277946113 SON/SF1/RBM25/HNRNPA1/NPM1/SCAF11/RBM39/LUC7L3/SRRM2/SRSF6/SRSF5/TRA2B/PNN/HSPA8/SNRPD2/HNRNPC/CIRBP/HNRNPA2B1/HNRNPA3/NCL/SRSF3 21 GO:0070482 response to oxygen levels 22/580 347/18722 0.00127124102376637 0.0177500932852308 MALAT1/HSP90B1/LDHA/EGR1/P4HB/SOD3/TGFBR3/SLC2A1/ENO1/ZFP36L1/SLC2A8/ATP6AP1/SLC9A1/ADM/DPP4/PMAIP1/CITED2/SLC6A4/BMP7/CAV1/RHOA/CYBA 22 GO:0015807 L-amino acid transport 8/580 69/18722 0.00128294543462429 0.0177500932852308 ITGB1/SLC3A2/SLC38A2/SLC1A5/SLC43A2/SLC38A1/SLC38A9/ARL6IP5 8 GO:0045669 positive regulation of osteoblast differentiation 8/580 69/18722 0.00128294543462429 0.0177500932852308 FBN2/JUND/LRP5/ATP6AP1/GLI3/BMP7/IL6ST/ATRAID 8 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 5/580 27/18722 0.00128612802346222 0.0177500932852308 APP/PBX1/BRD4/CDK1/RAB11A 5 GO:0033561 regulation of water loss via skin 5/580 27/18722 0.00128612802346222 0.0177500932852308 CLDN4/PLEC/MET/LSR/STMN1 5 GO:0014037 Schwann cell differentiation 6/580 40/18722 0.00134875317247536 0.0184917765206007 ITGB4/DAG1/PLEC/GPC1/ERBB3/CDK1 6 GO:0044275 cellular carbohydrate catabolic process 6/580 40/18722 0.00134875317247536 0.0184917765206007 GAA/GUSB/TPI1/AGL/HMGB1/PYGL 6 GO:0001704 formation of primary germ layer 11/580 121/18722 0.00135179617652209 0.0184917765206007 ITGB4/COL4A2/LAMB1/ITGAV/ITGB1/DUSP1/WLS/ITGB5/MMP15/GJA1/BMP7 11 GO:0022618 ribonucleoprotein complex assembly 16/580 220/18722 0.00142792240739849 0.0194758566475378 RPL13A/RPLP0/RPL23A/RPL6/SF1/EIF3A/PRKDC/SCAF11/LUC7L3/SRSF6/SRSF5/EIF2S2/PTGES3/EIF3H/SNRPD2/EIF4B 16 GO:0001755 neural crest cell migration 7/580 55/18722 0.0014764433781742 0.0199605172951432 LAMA5/NRP2/SEMA6A/SEMA6D/ISL1/FOLR1/BMP7 7 GO:0150104 transport across blood-brain barrier 9/580 87/18722 0.00147977558415881 0.0199605172951432 LRP2/LRP1/SLC2A1/SLC38A2/SLC1A5/SLC38A1/SLC19A1/TFRC/SLC16A12 9 GO:2000177 regulation of neural precursor cell proliferation 9/580 87/18722 0.00147977558415881 0.0199605172951432 LRP2/SPINT1/ADGRG1/SPINT2/GLI3/SLC6A4/ASPM/GNAI2/RHOA 9 GO:0043409 negative regulation of MAPK cascade 14/580 180/18722 0.00148062319217897 0.0199605172951432 FBLN1/DAG1/SEMA6A/DUSP1/DUSP6/EIF3A/IGF1R/DUSP9/HMGCR/MARVELD3/PPIA/BMP7/CAV1/TIMP3 14 GO:0034765 regulation of ion transmembrane transport 28/580 491/18722 0.00151089168582729 0.0203097029791408 AKAP9/AHNAK/TCAF1/APP/KCNN4/ITGB1/UTRN/GJA5/SLC43A2/SLC9A1/DIAPH1/CALM1/KIF5B/C4orf3/VAMP2/GSTO1/CAV1/STOM/TMSB4X/FXYD3/ARL6IP5/CALM2/VDAC1/YWHAE/YWHAH/CLIC3/CYBA/YWHAQ 28 GO:0034123 positive regulation of toll-like receptor signaling pathway 5/580 28/18722 0.0015262984881383 0.0204381422828011 RTN4/CAV1/NINJ1/HMGB1/CYBA 5 GO:0061572 actin filament bundle organization 13/580 161/18722 0.00154277173900712 0.0204381422828011 HSP90B1/MET/ITGB5/SLC9A1/TACSTD2/ROCK1/WASF2/ACTG1/ID1/PFN1/RHOA/STMN1/CDC42 13 GO:0003231 cardiac ventricle development 11/580 123/18722 0.00154396829554973 0.0204381422828011 LRP2/TGFBR3/SOX4/GJA5/ISL1/TRIP11/LMO4/TBX3/HECTD1/CITED2/DSP 11 GO:0000281 mitotic cytokinesis 8/580 71/18722 0.00154681274640851 0.0204381422828011 SON/RHOB/MYH10/SPTBN1/ROCK1/RASA1/RHOA/STMN1 8 GO:0072078 nephron tubule morphogenesis 8/580 71/18722 0.00154681274640851 0.0204381422828011 LAMA5/LGR4/PBX1/GLI3/TACSTD2/IRX2/MAGED1/GPC3 8 GO:0150116 regulation of cell-substrate junction organization 8/580 71/18722 0.00154681274640851 0.0204381422828011 LRP1/MACF1/IQGAP1/SLC9A1/ROCK1/PTPRA/ACTG1/RHOA 8 GO:0072006 nephron development 12/580 142/18722 0.00156948290059848 0.020663873629979 LAMA5/EGR1/LGR4/IQGAP1/ENPEP/PBX1/GLI3/TACSTD2/IRX2/MAGED1/GPC3/BMP7 12 GO:0009251 glucan catabolic process 4/580 17/18722 0.00157278246936413 0.020663873629979 GAA/AGL/HMGB1/PYGL 4 GO:0001843 neural tube closure 9/580 88/18722 0.00160412146213757 0.0210162504800052 LRP2/SPINT1/SPINT2/FOLR1/ADM/LMO4/HECTD1/CITED2/PFN1 9 GO:0001658 branching involved in ureteric bud morphogenesis 7/580 56/18722 0.00164312398226151 0.021466768655894 LAMA5/LGR4/PBX1/GLI3/TACSTD2/MAGED1/GPC3 7 GO:0030010 establishment of cell polarity 12/580 143/18722 0.00166632421057398 0.0217017348104466 ITGB1/KANK1/GJA1/FAT1/FERMT1/ROCK1/JAM3/FRMD4A/PRKCZ/RHOA/CDC42/DYNLT1 12 GO:0090263 positive regulation of canonical Wnt signaling pathway 10/580 106/18722 0.00167044099379486 0.0217017348104466 EGFR/LGR5/LGR4/KANK1/WLS/SOX4/GPC3/ATP6AP2/ASPM/CAV1 10 GO:0032409 regulation of transporter activity 20/580 310/18722 0.00168956383426343 0.0218890289503042 AKAP9/AHNAK/TCAF1/APP/ITGB1/UTRN/GJA1/SLC9A1/CALM1/KIF5B/C4orf3/VAMP2/GSTO1/CAV1/STOM/TMSB4X/FXYD3/CALM2/YWHAE/YWHAH 20 GO:0060606 tube closure 9/580 89/18722 0.00173671057630111 0.0224373358066013 LRP2/SPINT1/SPINT2/FOLR1/ADM/LMO4/HECTD1/CITED2/PFN1 9 GO:0051402 neuron apoptotic process 17/580 246/18722 0.00178489505599378 0.0229959748072772 GAPDH/JUN/LRP1/GRN/HSPA5/APP/NCSTN/ISL1/ERBB3/DDIT3/SIAH1/LGMN/TFAP2A/RASA1/GPX1/RHOA/CDC42 17 GO:0036503 ERAD pathway 10/580 107/18722 0.00179281797558419 0.023034244211166 HSP90B1/HSPA5/TMEM259/OS9/DNAJB14/CAV1/CCDC47/HM13/CANX/UBXN4 10 GO:0072088 nephron epithelium morphogenesis 8/580 73/18722 0.00185193404001106 0.0236630363189325 LAMA5/LGR4/PBX1/GLI3/TACSTD2/IRX2/MAGED1/GPC3 8 GO:0086003 cardiac muscle cell contraction 8/580 73/18722 0.00185193404001106 0.0236630363189325 AKAP9/DSG2/GJA5/GJA1/SLC9A1/DSC2/CAV1/DSP 8 GO:0031098 stress-activated protein kinase signaling cascade 17/580 247/18722 0.00186336526798495 0.0237438681134192 EGFR/GADD45B/APP/DUSP1/ZFP36L1/IGF1R/DUSP9/HMGCR/HACD3/MARVELD3/EMC10/PPIA/GADD45G/ARL6IP5/RHOA/HMGB1/CDC42 17 GO:0051896 regulation of protein kinase B signaling 14/580 185/18722 0.0019161500242379 0.024349764379045 LRP2/EGFR/DAG1/ITGB1/MET/TPBG/DDIT3/IGF1R/RTN4/TCF7L2/TXN/MYDGF/GPX1/IGF2 14 GO:0003012 muscle system process 26/580 452/18722 0.00194809832826409 0.0246534282399052 ATP2B1/AKAP9/GAA/DAG1/UTRN/ALDOA/ENO1/DSG2/GJA5/GJA1/SLC9A1/PABPN1/ROCK1/CALM1/TBX3/DSC2/GSTO1/CAV1/IL6ST/ASPH/DSP/TPM4/CALM2/RHOA/TPM3/CYBA 26 GO:0009306 protein secretion 22/580 359/18722 0.00195064751500432 0.0246534282399052 LRP1/EGFR/KCNN4/WLS/SOX4/MYH10/ERP29/ISL1/LRP5/GJA1/DPP4/HMGCR/KIF5B/TCF7L2/PPIA/FRMD4A/PDIA4/HMGN3/CANX/DYNLL1/FAM3B/PHPT1 22 GO:0044247 cellular polysaccharide catabolic process 4/580 18/18722 0.00197304262137736 0.024699667983753 GAA/AGL/HMGB1/PYGL 4 GO:0010632 regulation of epithelial cell migration 19/580 292/18722 0.00198061962666002 0.024699667983753 NRP2/GRN/RHOB/MACF1/SERPINF1/MET/PLPP3/TACSTD2/RTN4/NR2F2/MARVELD3/EMC10/TMSB4X/LGMN/PFN1/RHOA/HMGB1/CSNK2B/RAB11A 19 GO:0006458 'de novo' protein folding 6/580 43/18722 0.00198085920402922 0.024699667983753 HSPA5/HSPA1A/DNAJB14/DNAJB1/PTGES3/HSPA8 6 GO:0010171 body morphogenesis 6/580 43/18722 0.00198085920402922 0.024699667983753 DAG1/ANKRD11/GPC3/ATP6AP2/NIPBL/ARID5B 6 GO:0014002 astrocyte development 6/580 43/18722 0.00198085920402922 0.024699667983753 LRP1/EGFR/GRN/APP/CDK6/S100A9 6 GO:0030048 actin filament-based movement 11/580 127/18722 0.00199549980754662 0.0248156941307469 AKAP9/SYNE2/MYH10/DSG2/GJA5/GJA1/SLC9A1/DSC2/CAV1/WASF2/DSP 11 GO:0062197 cellular response to chemical stress 21/580 337/18722 0.00200135549152479 0.0248221450428848 JUN/FOS/EGFR/RHOB/P4HB/SOD3/SLC2A1/PLEC/MET/HSPA1A/ZFP36L1/DDIT3/PPIA/BMP7/CAV1/TXN/ARL6IP5/GPX1/PCNA/DHRS2/CDK1 21 GO:0035592 establishment of protein localization to extracellular region 22/580 360/18722 0.00201910685530501 0.0249217973739989 LRP1/EGFR/KCNN4/WLS/SOX4/MYH10/ERP29/ISL1/LRP5/GJA1/DPP4/HMGCR/KIF5B/TCF7L2/PPIA/FRMD4A/PDIA4/HMGN3/CANX/DYNLL1/FAM3B/PHPT1 22 GO:0001954 positive regulation of cell-matrix adhesion 7/580 58/18722 0.00202010698989413 0.0249217973739989 DAG1/UTRN/IQGAP1/FERMT1/ROCK1/CDK6/PRKCZ 7 GO:0034766 negative regulation of ion transmembrane transport 10/580 109/18722 0.00205931465040004 0.0253382868756894 SLC43A2/CALM1/C4orf3/GSTO1/CAV1/ARL6IP5/CALM2/VDAC1/YWHAE/YWHAQ 10 GO:0035303 regulation of dephosphorylation 11/580 128/18722 0.00212371313006613 0.0260617144272759 HSP90B1/SLC39A10/BOD1L1/PPP1R15A/ROCK1/CALM1/PPIA/GNAI2/CALM2/YWHAE/CSNK2B 11 GO:0048872 homeostasis of number of cells 18/580 272/18722 0.00214131281988483 0.026208541908643 ADGRG1/RPS6/TGFBR3/LGR4/UFL1/SOX4/NCSTN/HSPA1A/RPS17/ZFP36L1/PRKDC/PMAIP1/CITED2/JAM3/CDK6/FSTL1/HMGB1/HMGB2 18 GO:0002573 myeloid leukocyte differentiation 15/580 208/18722 0.00215550309074684 0.0263129786747075 FBN1/JUN/FOS/APP/ZFP36L1/ESRRA/ATP6AP1/TFRC/GPC3/CITED2/CD81/JUNB/CDK6/DHRS2/CDC42 15 GO:0014074 response to purine-containing compound 12/580 148/18722 0.00222717567457884 0.0270459374999117 JUN/AKAP9/FOS/HSP90B1/FOSB/LDHA/HSPA5/APP/DUSP1/BSG/ZFP36L1/SLC6A4 12 GO:0035148 tube formation 12/580 148/18722 0.00222717567457884 0.0270459374999117 LRP2/SPINT1/SPINT2/SOX4/FOLR1/ADM/IRX2/LMO4/HECTD1/CITED2/BMP7/PFN1 12 GO:0060711 labyrinthine layer development 6/580 44/18722 0.00223460800724168 0.0270655256293778 SPINT1/SPINT2/ZFP36L1/ADM/JUNB/BMP7 6 GO:0050767 regulation of neurogenesis 22/580 364/18722 0.00231374076936792 0.0279511904372213 LRP2/LRP1/EGFR/SPINT1/DAG1/GOLGA4/MACF1/SEMA6A/SEMA6D/SERPINF1/UFL1/GLI3/RTN4/CUX1/BMP7/ASPM/IL6ST/ID1/YWHAH/HMGB2/DYNLT1/RAB11A 22 GO:0006937 regulation of muscle contraction 13/580 169/18722 0.00237512998231064 0.0285445207951596 ATP2B1/AKAP9/ENO1/DSG2/GJA5/SLC9A1/CALM1/DSC2/GSTO1/CAV1/DSP/CALM2/RHOA 13 GO:0021543 pallium development 13/580 169/18722 0.00237512998231064 0.0285445207951596 LRP1/LAMB1/ADGRG1/SLC2A1/SLC38A2/GLI3/RTN4/TACC2/KIF5B/CDK6/ASPM/TRA2B/RHOA 13 GO:1900221 regulation of amyloid-beta clearance 4/580 19/18722 0.00243856332512176 0.0292295885715531 LRP1/LRPAP1/ROCK1/HMGCR 4 GO:0090162 establishment of epithelial cell polarity 5/580 31/18722 0.00244470220475901 0.0292295885715531 FAT1/FERMT1/FRMD4A/RHOA/CDC42 5 GO:0043491 protein kinase B signaling 15/580 211/18722 0.00247460658392909 0.0295112697996261 LRP2/EGFR/DAG1/ITGB1/MET/ZFP36L1/TPBG/DDIT3/IGF1R/RTN4/TCF7L2/TXN/MYDGF/GPX1/IGF2 15 GO:0010720 positive regulation of cell development 19/580 298/18722 0.00248873051382464 0.0296037995391264 LRP2/LRP1/EGFR/SPINT1/DAG1/GOLGA4/MACF1/P4HB/SERPINF1/UFL1/ATP6AP1/GLI3/PRKDC/CUX1/ASPM/IL6ST/TRIOBP/CDC42/RAB11A 19 GO:0035272 exocrine system development 6/580 45/18722 0.00251209091825968 0.0297242082903368 LAMA5/DAG1/WLS/BMP7/IGF2/CDC42 6 GO:0071364 cellular response to epidermal growth factor stimulus 6/580 45/18722 0.00251209091825968 0.0297242082903368 EGFR/EEF1A1/IQGAP1/ZFP36L1/ID1/NCL 6 GO:0048640 negative regulation of developmental growth 10/580 112/18722 0.00251802581517796 0.0297242082903368 SEMA6A/SEMA6D/GJA1/ADRB1/RTN4/CITED2/VGLL4/SLC6A4/LGMN/PLAC8 10 GO:0061326 renal tubule development 9/580 94/18722 0.00253718437023157 0.0298745430530305 LAMA5/LGR5/LGR4/PBX1/GLI3/TACSTD2/IRX2/MAGED1/GPC3 9 GO:0030336 negative regulation of cell migration 21/580 344/18722 0.00255799296420931 0.0300434981730745 LRP1/TCAF1/DAG1/RHOB/CDH1/ADGRG1/SEMA6D/SERPINF1/KANK1/DUSP1/GJA1/TACSTD2/DPP4/DLG5/CITED2/NR2F2/MARVELD3/MIF/RHOA/HMGB1/CSNK2B 21 GO:0021675 nerve development 8/580 77/18722 0.00260351116362134 0.0304668251735662 NRP2/DAG1/ISL1/ERBB3/GLI3/CTSV/CITED2/TFAP2A 8 GO:0110053 regulation of actin filament organization 18/580 277/18722 0.00260713747991386 0.0304668251735662 IQGAP2/KANK1/MET/SPTAN1/SPTBN1/SLC9A1/TACSTD2/ROCK1/TMSB4X/WASF2/TRIOBP/ACTG1/ID1/PFN1/RASA1/RHOA/STMN1/CDC42 18 GO:2001236 regulation of extrinsic apoptotic signaling pathway 12/580 151/18722 0.00263191703767365 0.0306793136396495 ITGAV/ITGA6/HSPA1A/PDIA3/PHIP/PMAIP1/TCF7L2/CAV1/TIMP3/SIAH2/GPX1/HMGB2 12 GO:0022613 ribonucleoprotein complex biogenesis 26/580 463/18722 0.00270217763308305 0.031375813163462 RPS21/RPL13A/RPLP0/RPL23A/RPS6/RPL6/RPL7/RPS16/RPL14/RPS25/RPS17/SF1/EIF3A/PRKDC/NPM1/SCAF11/LUC7L3/SRSF6/SRSF5/EIF2S2/PTGES3/EIF3H/SNRPD2/RAN/EIF4B/FBL 26 GO:0035264 multicellular organism growth 11/580 132/18722 0.00270516041250231 0.031375813163462 APP/PLEC/ZFP36L1/ADRB1/RBBP6/ATRX/NIPBL/ARID5B/LGMN/PLAC8/IGF2 11 GO:0001678 cellular glucose homeostasis 13/580 172/18722 0.00276958498442093 0.032043133737666 LRP1/SERPINF1/SOX4/LRP5/IGF1R/HMGCR/KIF5B/HMGN3/XBP1/TRA2B/DYNLL1/PHPT1/CYBA 13 GO:0050919 negative chemotaxis 6/580 46/18722 0.00281466532959067 0.0322003216124591 NRP2/ITGAV/SEMA6A/SEMA6D/DPP4/RHOA 6 GO:0032024 positive regulation of insulin secretion 8/580 78/18722 0.00282421268431248 0.0322003216124591 LRP1/SOX4/ISL1/GJA1/KIF5B/TCF7L2/DYNLL1/PHPT1 8 GO:0010644 cell communication by electrical coupling 5/580 32/18722 0.0028247110767326 0.0322003216124591 GJA5/GJA1/CALM1/CAV1/CALM2 5 GO:0033687 osteoblast proliferation 5/580 32/18722 0.0028247110767326 0.0322003216124591 ITGAV/LRP5/JUNB/ATRAID/RHOA 5 GO:0051497 negative regulation of stress fiber assembly 5/580 32/18722 0.0028247110767326 0.0322003216124591 MET/TACSTD2/WASF2/PFN1/STMN1 5 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 5/580 32/18722 0.0028247110767326 0.0322003216124591 HSPA1A/ERP29/DDIT3/PMAIP1/XBP1 5 GO:0010639 negative regulation of organelle organization 21/580 347/18722 0.00283371797136152 0.0322240153662651 KANK1/MET/DUSP1/HSPA1A/SPTAN1/SPTBN1/HNRNPA1/TACSTD2/ATRX/TFRC/NPM1/CENPF/BMP7/TMSB4X/TPR/WASF2/TRIOBP/PFN1/HNRNPC/GPX1/STMN1 21 GO:0003073 regulation of systemic arterial blood pressure 9/580 96/18722 0.00292932412211939 0.0331356123314978 ENPEP/GJA5/GJA1/ADRB1/ADM/ATP6AP2/NR2F2/RHOA/CYBA 9 GO:0044264 cellular polysaccharide metabolic process 9/580 96/18722 0.00292932412211939 0.0331356123314978 GAA/IL6ST/AGL/PHLDA2/PTGES3/HMGB1/IGF2/PYGL/UGP2 9 GO:0042593 glucose homeostasis 17/580 258/18722 0.00293525527425867 0.0331356123314978 LRP1/RPS6/SERPINF1/SOX4/LRP5/IGF1R/HMGCR/KIF5B/TCF7L2/HMGN3/XBP1/TRA2B/DYNLL1/FAM3B/PYGL/PHPT1/CYBA 17 GO:0046824 positive regulation of nucleocytoplasmic transport 7/580 62/18722 0.00297180213445215 0.0332540271446665 CDH1/GLI3/TCF7L2/TPR/RAN/YWHAE/CDK1 7 GO:0060675 ureteric bud morphogenesis 7/580 62/18722 0.00297180213445215 0.0332540271446665 LAMA5/LGR4/PBX1/GLI3/TACSTD2/MAGED1/GPC3 7 GO:0000272 polysaccharide catabolic process 4/580 20/18722 0.00297434428986912 0.0332540271446665 GAA/AGL/HMGB1/PYGL 4 GO:0043555 regulation of translation in response to stress 4/580 20/18722 0.00297434428986912 0.0332540271446665 PPP1R15A/NPM1/EIF4G1/EIF2AK4 4 GO:0032070 regulation of deoxyribonuclease activity 3/580 10/18722 0.00301617805668623 0.0333212449920372 NPM1/HMGB1/PCNA 3 GO:0040015 negative regulation of multicellular organism growth 3/580 10/18722 0.00301617805668623 0.0333212449920372 ADRB1/LGMN/PLAC8 3 GO:0072203 cell proliferation involved in metanephros development 3/580 10/18722 0.00301617805668623 0.0333212449920372 EGR1/GPC3/BMP7 3 GO:0098885 modification of postsynaptic actin cytoskeleton 3/580 10/18722 0.00301617805668623 0.0333212449920372 MYH10/PFN1/RHOA 3 GO:1904350 regulation of protein catabolic process in the vacuole 3/580 10/18722 0.00301617805668623 0.0333212449920372 LRP2/LRP1/CD81 3 GO:0051960 regulation of nervous system development 25/580 443/18722 0.00303102819233178 0.0333220163549403 LRP2/LRP1/EGFR/SPINT1/DAG1/GOLGA4/MACF1/SEMA6A/SEMA6D/SERPINF1/UFL1/CTSC/TPBG/GLI3/RTN4/DLG5/CUX1/BMP7/ASPM/IL6ST/ID1/YWHAH/HMGB2/DYNLT1/RAB11A 25 GO:0061564 axon development 26/580 467/18722 0.00303198111203268 0.0333220163549403 LAMA5/LRP1/NRP2/GRN/DAG1/GOLGA4/MACF1/SEMA6A/APP/SEMA6D/ITGB1/MYCBP2/BSG/ISL1/EPHB4/PTPRF/FOLR1/GLI3/RTN4/KIF5B/JAM3/SIAH1/BMP7/STMN1/DYNLT1/RAB11A 26 GO:0006470 protein dephosphorylation 18/580 281/18722 0.0030382430718967 0.0333220163549403 HSP90B1/SLC39A10/BOD1L1/DUSP1/DUSP6/PTPRF/PPP1R15A/ROCK1/CALM1/PPIA/PTPRA/CTDSPL/GNAI2/CALM2/PGP/YWHAE/CSNK2B/PHPT1 18 GO:0033500 carbohydrate homeostasis 17/580 259/18722 0.00305399680535778 0.0333220163549403 LRP1/RPS6/SERPINF1/SOX4/LRP5/IGF1R/HMGCR/KIF5B/TCF7L2/HMGN3/XBP1/TRA2B/DYNLL1/FAM3B/PYGL/PHPT1/CYBA 17 GO:0045927 positive regulation of growth 17/580 259/18722 0.00305399680535778 0.0333220163549403 LRP1/EGFR/GOLGA4/MACF1/TGFBR3/SLC9A1/PRKDC/CSH1/NIPBL/EIF4G1/S100A9/RHOA/IGF2/CDK1/CDC42/CYBA/RAB11A 17 GO:0006446 regulation of translational initiation 8/580 79/18722 0.00305923478468276 0.0333220163549403 RPL13A/PPP1R15A/NPM1/EIF4G1/EIF2AK4/TPR/EIF3H/EIF4B 8 GO:0051168 nuclear export 12/580 154/18722 0.00309455270485169 0.0336184255949809 HNRNPA1/PABPN1/NPM1/TCF7L2/NEMF/THOC2/TPR/TXN/HNRNPA2B1/RAN/YWHAE/SRSF3 12 GO:0090287 regulation of cellular response to growth factor stimulus 19/580 304/18722 0.00310205494346821 0.0336184255949809 FBN1/FBN2/LRP2/GLG1/HSPA5/PEG10/SEMA6A/CRIM1/LTBP1/TGFBR3/HSPA1A/GPC1/FOLR1/FERMT1/GPC3/CITED2/CAV1/FSTL1/CDKN1C 19 GO:0030705 cytoskeleton-dependent intracellular transport 14/580 195/18722 0.00310813223088406 0.0336184255949809 ARMCX3/DYNC1H1/APP/SYNE2/DST/PURA/KIF5B/HOOK2/ARHGAP21/HSPA8/PRKCZ/TUBA1B/CDC42/TUBA1C 14 GO:1903170 negative regulation of calcium ion transmembrane transport 6/580 47/18722 0.00314370545898592 0.0339243018323516 CALM1/C4orf3/GSTO1/CALM2/VDAC1/YWHAE 6 GO:0010975 regulation of neuron projection development 25/580 445/18722 0.0032135751805733 0.0345980050112186 LRP1/GRN/TENM3/HSPA5/GOLGA4/MACF1/SEMA6A/ITGA6/SEMA6D/SERPINF1/KANK1/IQGAP1/PTPRF/RTN4/CUX1/THOC2/BMP7/CFL1/MYLIP/ID1/S100A9/RHOA/YWHAH/DYNLT1/RAB11A 25 GO:0030326 embryonic limb morphogenesis 10/580 116/18722 0.00325328695496077 0.0346530888349543 FBN2/FRAS1/LRP5/PBX1/GLI3/TBX3/GPC3/NIPBL/BMP7/TFAP2A 10 GO:0035113 embryonic appendage morphogenesis 10/580 116/18722 0.00325328695496077 0.0346530888349543 FBN2/FRAS1/LRP5/PBX1/GLI3/TBX3/GPC3/NIPBL/BMP7/TFAP2A 10 GO:0045664 regulation of neuron differentiation 14/580 196/18722 0.00325496599671747 0.0346530888349543 APP/ISL1/PBX1/GLI3/ROCK1/ZFHX3/SLC6A4/EIF4G1/EIF2AK4/BMP7/ASPM/TUG1/RHOA/YWHAH 14 GO:0072171 mesonephric tubule morphogenesis 7/580 63/18722 0.00325594491956032 0.0346530888349543 LAMA5/LGR4/PBX1/GLI3/TACSTD2/MAGED1/GPC3 7 GO:1904589 regulation of protein import 7/580 63/18722 0.00325594491956032 0.0346530888349543 CDH1/GLI3/FERMT1/TPR/HSPA8/RAN/CDK1 7 GO:0051403 stress-activated MAPK cascade 16/580 239/18722 0.00329198616066884 0.0348214088629391 EGFR/GADD45B/APP/DUSP1/ZFP36L1/IGF1R/DUSP9/HMGCR/HACD3/MARVELD3/EMC10/PPIA/GADD45G/ARL6IP5/HMGB1/CDC42 16 GO:0006979 response to oxidative stress 25/580 446/18722 0.0033082791802951 0.0348214088629391 JUN/FOS/EGFR/LDHA/RHOB/APP/P4HB/SOD3/MET/DUSP1/HSPA1A/DHCR24/BTG1/PPIA/BMP7/MSRB2/TXN/GPX3/TRA2B/ARL6IP5/GPX1/TXNIP/PCNA/DHRS2/CDK1 25 GO:0001570 vasculogenesis 8/580 80/18722 0.00330919430604581 0.0348214088629391 ITGAV/TGFBR3/ZFP36L1/ADM/CITED2/JUNB/CAV1/RASA1 8 GO:0007422 peripheral nervous system development 8/580 80/18722 0.00330919430604581 0.0348214088629391 ITGB4/DAG1/PLEC/GPC1/ISL1/ERBB3/CITED2/CDK1 8 GO:0120193 tight junction organization 8/580 80/18722 0.00330919430604581 0.0348214088629391 SVEP1/CLDN4/PLEC/GJA1/LSR/ROCK1/MARVELD3/ACTG1 8 GO:0003333 amino acid transmembrane transport 9/580 98/18722 0.00336782124494119 0.0353583219192359 ITGB1/SLC3A2/SLC38A2/SLC38A10/SLC1A5/SLC43A2/SLC38A1/SLC38A9/ARL6IP5 9 GO:0022409 positive regulation of cell-cell adhesion 18/580 284/18722 0.00339918893556172 0.0356072696831026 CD46/SOX4/PLPP3/NFAT5/GLI3/DPP4/TFRC/CITED2/CD81/BMP7/CAV1/IL6ST/XBP1/CD55/PRKCZ/RHOA/HMGB1/IGF2 18 GO:0010952 positive regulation of peptidase activity 14/580 197/18722 0.00340742588299635 0.0356133433299237 GRN/FBLN1/CLDN4/CTSD/APP/NCSTN/PMAIP1/CAV1/ASPH/LGMN/S100A9/ARL6IP5/RHOA/HMGB1 14 GO:0035051 cardiocyte differentiation 12/580 156/18722 0.00343801863298785 0.0358525216637366 EGFR/TGFBR3/ITGB1/PLEC/ISL1/FOLR1/SLC9A1/TBX3/CITED2/BMP7/CDK1/CACYBP 12 GO:0070371 ERK1 and ERK2 cascade 20/580 330/18722 0.00347169851904354 0.0361227512574307 LRP1/EGFR/FBLN1/ITGAV/SEMA6A/APP/DUSP1/DUSP6/ZFP36L1/EIF3A/TPBG/ATP6AP1/DUSP9/HMGCR/MIF/TIMP3/GNAI2/PRKCZ/HMGB1/CDK1 20 GO:0044772 mitotic cell cycle phase transition 24/580 424/18722 0.0034999126436717 0.0362612219187338 EGFR/APP/RPS6/ITGB1/DUSP1/SOX4/ZFP36L1/ADAMTS1/PBX1/DDB1/PRKDC/CALM1/CENPF/BRD4/CDK6/EIF4G1/TPR/CTDSPL/E2F4/CCND3/CALM2/CDK1/ANAPC11/RAB11A 24 GO:0015804 neutral amino acid transport 6/580 48/18722 0.00350059957891022 0.0362612219187338 SLC3A2/SLC38A2/SLC1A5/SLC43A2/SLC38A1/SLC38A9 6 GO:0032507 maintenance of protein location in cell 7/580 64/18722 0.00356035321876063 0.0365680936316453 HSPA5/GPAA1/GJA1/OS9/CAV1/TMSB4X/TXN 7 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 7/580 64/18722 0.00356035321876063 0.0365680936316453 LRP1/LRP5/HMGCR/KIF5B/HMGN3/DYNLL1/PHPT1 7 GO:0014032 neural crest cell development 8/580 81/18722 0.00357471749795627 0.0365680936316453 LAMA5/NRP2/SEMA6A/SEMA6D/ISL1/FOLR1/CITED2/BMP7 8 GO:0015711 organic anion transport 21/580 354/18722 0.0035755768998341 0.0365680936316453 LRP2/SLC26A2/ITGB1/SLC3A2/SLC2A1/PSAP/SLC22A11/SLC38A2/SLC1A5/SLC2A8/SLC52A1/GJA1/SLC43A2/FOLR1/SLC38A1/SLC52A2/SLC19A1/SLC16A12/SLC38A9/MFSD10/ARL6IP5 21 GO:0032516 positive regulation of phosphoprotein phosphatase activity 4/580 21/18722 0.00358526138379494 0.0365680936316453 SLC39A10/PPP1R15A/CALM1/CALM2 4 GO:0038083 peptidyl-tyrosine autophosphorylation 4/580 21/18722 0.00358526138379494 0.0365680936316453 EGFR/IQGAP1/IGF1R/CAV1 4 GO:0150105 protein localization to cell-cell junction 4/580 21/18722 0.00358526138379494 0.0365680936316453 LSR/DLG5/ACTG1/DSP 4 GO:0006986 response to unfolded protein 11/580 137/18722 0.00360576116238423 0.0366905775653008 HSPA5/UFL1/HSPA1A/SERPINH1/DDIT3/PPP1R15A/OS9/XBP1/DNAJB1/HSPA8/UBXN4 11 GO:1902107 positive regulation of leukocyte differentiation 12/580 157/18722 0.00362093637980501 0.0366905775653008 JUN/FOS/CD46/SOX4/ZFP36L1/ATP6AP1/GLI3/PRKDC/XBP1/PRKCZ/RHOA/HMGB1 12 GO:1903708 positive regulation of hemopoiesis 12/580 157/18722 0.00362093637980501 0.0366905775653008 JUN/FOS/CD46/SOX4/ZFP36L1/ATP6AP1/GLI3/PRKDC/XBP1/PRKCZ/RHOA/HMGB1 12 GO:0035308 negative regulation of protein dephosphorylation 5/580 34/18722 0.00370990330380455 0.0375103484043369 BOD1L1/PPP1R15A/ROCK1/GNAI2/YWHAE 5 GO:0030900 forebrain development 22/580 379/18722 0.00376387781354034 0.0379735264875838 LRP2/LRP1/LAMB1/NRP2/CDH1/ADGRG1/APP/SLC2A1/SLC38A2/ISL1/GLI3/RTN4/TACC2/ATRX/TBX3/KIF5B/NR2F2/CDK6/ASPM/DNAJB1/TRA2B/RHOA 22 GO:0043488 regulation of mRNA stability 12/580 158/18722 0.00381161754750772 0.038371933362464 ZFP36L1/TNRC6A/YBX1/ROCK1/NPM1/PUM1/FUS/HNRNPC/HNRNPD/CIRBP/CARHSP1/SERBP1 12 GO:0051047 positive regulation of secretion 19/580 310/18722 0.00383672897648141 0.0385413098695789 LRP1/EGFR/KCNN4/WLS/SOX4/MYH10/ISL1/GJA1/ATP6AP1/KIF5B/TCF7L2/SLC6A4/PPIA/FRMD4A/XBP1/GNAI2/DYNLL1/PHPT1/CYBA 19 GO:0061640 cytoskeleton-dependent cytokinesis 9/580 100/18722 0.00385633889322069 0.0386266268299926 SON/RHOB/PLEC/MYH10/SPTBN1/ROCK1/RASA1/RHOA/STMN1 9 GO:0048524 positive regulation of viral process 7/580 65/18722 0.00388593634832916 0.0386266268299926 P4HB/DDB1/HACD3/PKN2/PPIA/RSF1/STOM 7 GO:1902475 L-alpha-amino acid transmembrane transport 7/580 65/18722 0.00388593634832916 0.0386266268299926 ITGB1/SLC3A2/SLC1A5/SLC43A2/SLC38A1/SLC38A9/ARL6IP5 7 GO:0034332 adherens junction organization 6/580 49/18722 0.00388674722778682 0.0386266268299926 CDH1/PLEC/DLG5/JAM3/DSP/CDC42 6 GO:0045778 positive regulation of ossification 6/580 49/18722 0.00388674722778682 0.0386266268299926 FBN2/ATP2B1/NIPBL/BMP7/TFAP2A/ATRAID 6 GO:0006941 striated muscle contraction 13/580 179/18722 0.00390066224367938 0.0386822603312426 AKAP9/GAA/ALDOA/DSG2/GJA5/GJA1/SLC9A1/CALM1/DSC2/GSTO1/CAV1/DSP/CALM2 13 GO:0000302 response to reactive oxygen species 15/580 222/18722 0.00399721579325036 0.0394305110193207 JUN/FOS/EGFR/LDHA/RHOB/SOD3/MET/DUSP1/BMP7/TXN/TRA2B/GPX1/TXNIP/PCNA/CDK1 15 GO:0035966 response to topologically incorrect protein 12/580 159/18722 0.00401029655407317 0.0394305110193207 HSPA5/UFL1/HSPA1A/SERPINH1/DDIT3/PPP1R15A/OS9/DNAJB14/XBP1/DNAJB1/HSPA8/UBXN4 12 GO:0001731 formation of translation preinitiation complex 3/580 11/18722 0.0040524154519964 0.0394305110193207 RPL13A/EIF2S2/EIF4B 3 GO:0003093 regulation of glomerular filtration 3/580 11/18722 0.0040524154519964 0.0394305110193207 GJA5/GJA1/CYBA 3 GO:0036490 regulation of translation in response to endoplasmic reticulum stress 3/580 11/18722 0.0040524154519964 0.0394305110193207 PPP1R15A/EIF4G1/EIF2AK4 3 GO:0051657 maintenance of organelle location 3/580 11/18722 0.0040524154519964 0.0394305110193207 AKAP9/ARHGAP21/ASPM 3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 3/580 11/18722 0.0040524154519964 0.0394305110193207 CALM1/GSTO1/CALM2 3 GO:0070417 cellular response to cold 3/580 11/18722 0.0040524154519964 0.0394305110193207 SLC9A1/EIF2AK4/NFKBIA 3 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction 3/580 11/18722 0.0040524154519964 0.0394305110193207 CALM1/CAV1/CALM2 3 GO:0032535 regulation of cellular component size 22/580 382/18722 0.00413037952769218 0.0401052091509318 LRP1/GOLGA4/MACF1/SEMA6A/IQGAP2/SEMA6D/KCNN4/KANK1/SPTAN1/SPTBN1/SLC12A9/PPP1R15A/RTN4/NPM1/TMSB4X/WASF2/TRIOBP/E2F4/PFN1/RASA1/RHOA/RAB11A 22 GO:0048678 response to axon injury 8/580 83/18722 0.00415500343344525 0.0402602520186539 LRP1/GRN/DAG1/ISL1/PTPRF/FOLR1/JAM3/CDK1 8 GO:0032232 negative regulation of actin filament bundle assembly 5/580 35/18722 0.00421987278340881 0.0407191458830589 MET/TACSTD2/WASF2/PFN1/STMN1 5 GO:1905898 positive regulation of response to endoplasmic reticulum stress 5/580 35/18722 0.00421987278340881 0.0407191458830589 TMEM259/DDIT3/PMAIP1/CAV1/XBP1 5 GO:0030177 positive regulation of Wnt signaling pathway 11/580 140/18722 0.00425197755017076 0.0407538666944354 EGFR/MACF1/LGR5/LGR4/KANK1/WLS/SOX4/GPC3/ATP6AP2/ASPM/CAV1 11 GO:0035024 negative regulation of Rho protein signal transduction 4/580 22/18722 0.00427604535516759 0.0407538666944354 ITGB1/KANK1/MET/STMN1 4 GO:0048026 positive regulation of mRNA splicing, via spliceosome 4/580 22/18722 0.00427604535516759 0.0407538666944354 TRA2B/HSPA8/CIRBP/NCL 4 GO:0051412 response to corticosterone 4/580 22/18722 0.00427604535516759 0.0407538666944354 ATP2B1/FOS/FOSB/CALM1 4 GO:0099563 modification of synaptic structure 4/580 22/18722 0.00427604535516759 0.0407538666944354 MYH10/PFN1/RHOA/CDC42 4 GO:0140467 integrated stress response signaling 4/580 22/18722 0.00427604535516759 0.0407538666944354 HSPA5/DDIT3/PPP1R15A/EIF2AK4 4 GO:0003007 heart morphogenesis 16/580 246/18722 0.00435549015661244 0.0413416014661316 LRP2/NRP2/GAA/TGFBR3/SOX4/GJA5/ISL1/EPHB4/ADAMTS1/FOLR1/RTN4/TBX3/CITED2/NIPBL/BMP7/DSP 16 GO:0031668 cellular response to extracellular stimulus 16/580 246/18722 0.00435549015661244 0.0413416014661316 JUN/ATP2B1/FOS/HSPA5/SLC2A1/PLEC/SLC38A2/TNRC6A/FOLR1/HNRNPA1/CTSV/PMAIP1/EIF4G1/EIF2AK4/XBP1/HSPA8 16 GO:0003206 cardiac chamber morphogenesis 10/580 121/18722 0.00440205388818844 0.0416137248657814 LRP2/NRP2/TGFBR3/SOX4/ISL1/ADAMTS1/TBX3/CITED2/BMP7/DSP 10 GO:0042752 regulation of circadian rhythm 10/580 121/18722 0.00440205388818844 0.0416137248657814 ADRB1/DDB1/PRKDC/GNAQ/ZFHX3/MAGED1/NR2F6/SIAH2/HNRNPD/CDK1 10 GO:0006405 RNA export from nucleus 8/580 84/18722 0.00447106040176189 0.0420099028860496 HNRNPA1/PABPN1/NPM1/THOC2/TPR/HNRNPA2B1/RAN/SRSF3 8 GO:0006835 dicarboxylic acid transport 8/580 84/18722 0.00447106040176189 0.0420099028860496 LRP2/SLC26A2/ITGB1/SLC1A5/GJA1/FOLR1/SLC19A1/ARL6IP5 8 GO:0045445 myoblast differentiation 8/580 84/18722 0.00447106040176189 0.0420099028860496 PLEC/ZFP36L1/ISL1/BTG1/DDIT3/HMGCR/TBX3/TCF7L2 8 GO:0008584 male gonad development 11/580 141/18722 0.00448675574960661 0.0420723810310894 LRP2/ADGRG1/SF1/CTSV/ATRX/KDM5A/CITED2/ASPM/ARID5B/EIF2S2/HMGB2 11 GO:0045786 negative regulation of cell cycle 22/580 385/18722 0.00452618846798834 0.0423567456028446 EGFR/RHOB/DUSP1/SOX4/ZFP36L1/PPP1R10/TP53I13/BTG1/PRKDC/ATRX/NPM1/NR2F2/CENPF/CDK6/EIF2AK4/BMP7/TPR/CTDSPL/CDKN1C/HPGD/CDK1/GMNN 22 GO:0016049 cell growth 26/580 482/18722 0.0045891838136429 0.0428600279462914 LRP1/EGFR/NRP2/GOLGA4/MACF1/SEMA6A/APP/SEMA6D/ITGB1/IQGAP1/HSPA1A/ENO1/GJA1/SLC9A1/BTG1/RTN4/NPM1/VGLL4/EIF4G1/EIF2AK4/S100A9/PRKCZ/RHOA/CDC42/CYBA/RAB11A 26 GO:0061077 chaperone-mediated protein folding 7/580 67/18722 0.00460431158949058 0.0429151366787989 HSPA5/HSPA1A/PDIA4/DNAJB14/DNAJB1/PTGES3/HSPA8 7 GO:1901888 regulation of cell junction assembly 14/580 204/18722 0.00464576120623151 0.0432148707403655 LRP1/MACF1/APP/IQGAP1/GJA1/TPBG/SLC9A1/ROCK1/DLG5/EIF4G1/PTPRA/CAV1/ACTG1/RHOA 14 GO:0090277 positive regulation of peptide hormone secretion 9/580 103/18722 0.00469118475304319 0.043550299972862 LRP1/EGFR/SOX4/ISL1/GJA1/KIF5B/TCF7L2/DYNLL1/PHPT1 9 GO:0033002 muscle cell proliferation 16/580 248/18722 0.00470626977243451 0.0436033081904241 JUN/EGFR/TGFBR3/SF1/ADAMTS1/GJA1/PRKDC/HMGCR/CITED2/TCF7L2/VGLL4/GNAI2/RHOA/HPGD/CDK1/CYBA 16 GO:0046546 development of primary male sexual characteristics 11/580 142/18722 0.00473171759188974 0.0437519254868374 LRP2/ADGRG1/SF1/CTSV/ATRX/KDM5A/CITED2/ASPM/ARID5B/EIF2S2/HMGB2 11 GO:0051385 response to mineralocorticoid 5/580 36/18722 0.00477792824116318 0.0440915560508928 ATP2B1/FOS/FOSB/CALM1/CYBA 5 GO:0030433 ubiquitin-dependent ERAD pathway 8/580 85/18722 0.00480526823851431 0.0442560447075843 HSP90B1/HSPA5/OS9/DNAJB14/CAV1/CCDC47/CANX/UBXN4 8 GO:0007411 axon guidance 15/580 227/18722 0.0049063191106302 0.0450084619004755 LAMA5/LRP1/NRP2/DAG1/SEMA6A/APP/SEMA6D/MYCBP2/BSG/ISL1/EPHB4/GLI3/KIF5B/SIAH1/BMP7 15 GO:0098657 import into cell 15/580 227/18722 0.0049063191106302 0.0450084619004755 LRP2/SLC39A10/ITGB1/SLC3A2/SLC2A1/SLC1A5/SLC12A9/SLC43A2/FOLR1/SLC38A1/SLC9A1/SLC19A1/SLC27A2/SLC6A4/ARL6IP5 15 GO:0032922 circadian regulation of gene expression 7/580 68/18722 0.00499896579837569 0.0457680904099318 EGR1/LGR4/MYCBP2/ZFHX3/MAGED1/KDM5A/ID1 7 GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 4/580 23/18722 0.00505126323115259 0.04606553978057 ENPEP/ATP6AP2/RHOA/CYBA 4 GO:0018279 protein N-linked glycosylation via asparagine 4/580 23/18722 0.00505126323115259 0.04606553978057 RPN2/DDOST/MGAT1/TUSC3 4 GO:0097485 neuron projection guidance 15/580 228/18722 0.00510685319199863 0.0464813585048642 LAMA5/LRP1/NRP2/DAG1/SEMA6A/APP/SEMA6D/MYCBP2/BSG/ISL1/EPHB4/GLI3/KIF5B/SIAH1/BMP7 15 GO:0014031 mesenchymal cell development 8/580 86/18722 0.00515829116680089 0.0467664955493001 LAMA5/NRP2/SEMA6A/SEMA6D/ISL1/FOLR1/CITED2/BMP7 8 GO:0048864 stem cell development 8/580 86/18722 0.00515829116680089 0.0467664955493001 LAMA5/NRP2/SEMA6A/SEMA6D/ISL1/FOLR1/CITED2/BMP7 8 GO:0009410 response to xenobiotic stimulus 25/580 462/18722 0.0051747927861266 0.0467755598650357 JUN/FOS/EGFR/FOSB/LDHA/HSPA5/CDH1/RPN2/DUSP6/TFRC/POR/CENPF/SLC6A4/GSTO1/CYP2J2/ADIRF/PLIN2/TYMS/GPX1/HADHA/RHOA/TXNIP/PCNA/CDK1/CYBA 25 GO:0034249 negative regulation of cellular amide metabolic process 17/580 273/18722 0.00517940514523617 0.0467755598650357 GAPDH/RPL13A/ZFP36L1/TNRC6A/YBX1/PURA/ROCK1/RTN4/PUM1/ORMDL1/EIF4G1/EIF2AK4/TPR/TYMS/HNRNPD/CIRBP/NCL 17 GO:0021545 cranial nerve development 6/580 52/18722 0.00523481701435175 0.046863900093757 NRP2/ISL1/ERBB3/GLI3/CITED2/TFAP2A 6 GO:0043392 negative regulation of DNA binding 6/580 52/18722 0.00523481701435175 0.046863900093757 JUN/DDIT3/RSF1/TMSB4X/ID1/NFKBIA 6 GO:0106106 cold-induced thermogenesis 11/580 144/18722 0.00525341160095254 0.046863900093757 DYNC1H1/LGR4/GJA1/ADRB1/DDIT3/IGF1R/PRLR/CAV1/ID1/GADD45G/PLAC8 11 GO:0120161 regulation of cold-induced thermogenesis 11/580 144/18722 0.00525341160095254 0.046863900093757 DYNC1H1/LGR4/GJA1/ADRB1/DDIT3/IGF1R/PRLR/CAV1/ID1/GADD45G/PLAC8 11 GO:0009886 post-embryonic animal morphogenesis 3/580 12/18722 0.00527987178007497 0.046863900093757 FBN1/EFEMP1/ATRX 3 GO:0043696 dedifferentiation 3/580 12/18722 0.00527987178007497 0.046863900093757 CDK6/NCOA3/HNRNPD 3 GO:0043697 cell dedifferentiation 3/580 12/18722 0.00527987178007497 0.046863900093757 CDK6/NCOA3/HNRNPD 3 GO:0061307 cardiac neural crest cell differentiation involved in heart development 3/580 12/18722 0.00527987178007497 0.046863900093757 FOLR1/CITED2/BMP7 3 GO:0061308 cardiac neural crest cell development involved in heart development 3/580 12/18722 0.00527987178007497 0.046863900093757 FOLR1/CITED2/BMP7 3 GO:0050796 regulation of insulin secretion 12/580 165/18722 0.00538385932243553 0.0476128763197936 LRP1/SOX4/ISL1/LRP5/GJA1/DPP4/HMGCR/KIF5B/TCF7L2/HMGN3/DYNLL1/PHPT1 12 GO:0140694 non-membrane-bounded organelle assembly 21/580 367/18722 0.00538472864850815 0.0476128763197936 RPLP0/RPL23A/DYNC1H1/KRT19/ITGB1/RPL6/PLEC/PRRC2C/HSPA1A/PRKDC/NPM1/CENPF/ASPM/TPR/ACTG1/KRT8/E2F4/RHOA/CIRBP/CENPN/RAB11A 21 GO:0090257 regulation of muscle system process 16/580 252/18722 0.00547705851359787 0.0483373797850924 ATP2B1/AKAP9/DAG1/ENO1/DSG2/GJA5/SLC9A1/ROCK1/CALM1/DSC2/GSTO1/CAV1/IL6ST/DSP/CALM2/RHOA 16 GO:0048041 focal adhesion assembly 8/580 87/18722 0.0055307990739039 0.0485576953395817 LRP1/MACF1/IQGAP1/SLC9A1/ROCK1/PTPRA/ACTG1/RHOA 8 GO:0018210 peptidyl-threonine modification 10/580 125/18722 0.00553334305095212 0.0485576953395817 APP/PRKDC/ROCK1/CALM1/GALNT11/EIF4G1/BMP7/CALM2/CDK1/CSNK2B 10 GO:1904375 regulation of protein localization to cell periphery 10/580 125/18722 0.00553334305095212 0.0485576953395817 LRP1/EGFR/DAG1/ITGB1/SPTBN1/KIF5B/HECTD1/TMEM59/PRKCZ/RAB11A 10 GO:0060538 skeletal muscle organ development 12/580 166/18722 0.0056453545317898 0.0491151730362413 FOS/DAG1/EGR1/PLEC/GPC1/HMGCR/CITED2/NR2F2/CAV1/GPX1/RHOA/IGF2 12 GO:0061013 regulation of mRNA catabolic process 12/580 166/18722 0.0056453545317898 0.0491151730362413 ZFP36L1/TNRC6A/YBX1/ROCK1/NPM1/PUM1/FUS/HNRNPC/HNRNPD/CIRBP/CARHSP1/SERBP1 12 GO:0002793 positive regulation of peptide secretion 9/580 106/18722 0.00566023064876916 0.0491151730362413 LRP1/EGFR/SOX4/ISL1/GJA1/KIF5B/TCF7L2/DYNLL1/PHPT1 9 GO:0046620 regulation of organ growth 9/580 106/18722 0.00566023064876916 0.0491151730362413 TGFBR3/DUSP6/GJA1/DUSP9/CITED2/VGLL4/SLC6A4/IGF2/CDK1 9 GO:0046822 regulation of nucleocytoplasmic transport 9/580 106/18722 0.00566023064876916 0.0491151730362413 CDH1/GLI3/FERMT1/TCF7L2/TPR/TXN/RAN/YWHAE/CDK1 9 GO:1905477 positive regulation of protein localization to membrane 9/580 106/18722 0.00566023064876916 0.0491151730362413 LRP1/EGFR/TCAF1/ITGB1/SPTBN1/KIF5B/CD81/STOM/RAB11A 9 GO:0097305 response to alcohol 16/580 253/18722 0.00568495794339125 0.0492378759678077 ATP2B1/FOS/FOSB/DAG1/CDH1/TGFBR3/HMGCR/CALM1/EEF1B2/TUFM/TYMS/HNRNPD/RHOA/HPGD/CDK1/CYBA 16 GO:1901990 regulation of mitotic cell cycle phase transition 18/580 299/18722 0.00577897856920755 0.0499591623148408 EGFR/APP/DUSP1/SOX4/ZFP36L1/ADAMTS1/PBX1/DDB1/PRKDC/CENPF/BRD4/EIF4G1/TPR/CTDSPL/CCND3/CDK1/ANAPC11/RAB11A 18 GO:0033674 positive regulation of kinase activity 25/580 467/18722 0.0059129081323552 0.0506667965249362 EGFR/DAG1/EGR1/MET/IQGAP1/ERP29/EPHB4/ERBB3/IGF1R/LMO4/CALM1/MAGED1/NPM1/CD81/PPIA/PRLR/TXN/CCND3/CALM2/PRKCZ/RHOA/CKS1B/HMGB1/IGF2/CDC42 25 GO:0018196 peptidyl-asparagine modification 4/580 24/18722 0.00591530219588053 0.0506667965249362 RPN2/DDOST/MGAT1/TUSC3 4 GO:0021801 cerebral cortex radial glia-guided migration 4/580 24/18722 0.00591530219588053 0.0506667965249362 LAMB1/ADGRG1/GLI3/RTN4 4 GO:0022030 telencephalon glial cell migration 4/580 24/18722 0.00591530219588053 0.0506667965249362 LAMB1/ADGRG1/GLI3/RTN4 4 GO:0030859 polarized epithelial cell differentiation 4/580 24/18722 0.00591530219588053 0.0506667965249362 FAT1/DLG5/RHOA/CDC42 4 GO:0032271 regulation of protein polymerization 15/580 232/18722 0.00597646862582407 0.0510966095196834 AKAP9/IQGAP2/CLIP1/KANK1/MET/HSPA1A/SPTAN1/SPTBN1/TMSB4X/WASF2/TRIOBP/PFN1/RASA1/RHOA/STMN1 15 GO:0005976 polysaccharide metabolic process 9/580 107/18722 0.0060154012003882 0.051241082386457 GAA/IL6ST/AGL/PHLDA2/PTGES3/HMGB1/IGF2/PYGL/UGP2 9 GO:0006275 regulation of DNA replication 9/580 107/18722 0.0060154012003882 0.051241082386457 JUN/EGFR/RBBP6/ATRX/PCNA/CDK1/GMNN/CDC42/CACYBP 9 GO:0042596 fear response 5/580 38/18722 0.00604767697679228 0.0514218384260711 GJA1/ADRB1/DPP4/EIF4G1/VDAC1 5 GO:0006417 regulation of translation 25/580 468/18722 0.00607054578832287 0.0515220957326454 GAPDH/RPL13A/APP/SOX4/ZFP36L1/TNRC6A/YBX1/PRKDC/PPP1R15A/PURA/ROCK1/NPM1/PUM1/NEMF/EIF4G1/EIF2AK4/TPR/PKM/EIF3H/TYMS/HNRNPD/RHOA/CIRBP/NCL/EIF4B 25 GO:1902850 microtubule cytoskeleton organization involved in mitosis 11/580 147/18722 0.00612004113345891 0.0518475615878276 DYNC1H1/ITGB1/HSPA1A/GJA1/TACC2/TPR/RHOA/RAN/STMN1/DYNLT1/RAB11A 11 GO:0042886 amide transport 18/580 301/18722 0.00617998581831315 0.0522602073472263 LRP2/LRP1/EGFR/PSAP/SOX4/ISL1/LRP5/GJA1/FOLR1/DPP4/SLC19A1/HMGCR/KIF5B/TCF7L2/HMGN3/DYNLL1/FAM3B/PHPT1 18 GO:0001706 endoderm formation 6/580 54/18722 0.00630570897805996 0.0530340912422366 COL4A2/LAMB1/ITGAV/DUSP1/ITGB5/MMP15 6 GO:0070839 metal ion export 6/580 54/18722 0.00630570897805996 0.0530340912422366 ATP2B1/SLC9A1/CALM1/SLC40A1/CALM2/YWHAE 6 GO:0086002 cardiac muscle cell action potential involved in contraction 6/580 54/18722 0.00630570897805996 0.0530340912422366 DSG2/GJA5/GJA1/DSC2/CAV1/DSP 6 GO:0051051 negative regulation of transport 25/580 470/18722 0.00639628523998784 0.0536987773487066 ITGAV/LMAN1/LRPAP1/GABRE/ERP29/GJA1/SLC43A2/ERBB3/FERMT1/HMGCR/CALM1/OS9/FRMD4A/C4orf3/GSTO1/CAV1/TPR/TXN/GNAI2/ARL6IP5/CALM2/HMGB1/VDAC1/YWHAE/YWHAQ 25 GO:0015849 organic acid transport 18/580 303/18722 0.00660337086659717 0.0553122233403314 LRP2/SLC26A2/ITGB1/SLC3A2/SLC2A1/SLC38A2/SLC38A10/SLC1A5/GJA1/SLC43A2/FOLR1/SLC38A1/SLC19A1/SLC27A2/SLC38A9/CROT/PLIN2/ARL6IP5 18 GO:0050821 protein stabilization 13/580 191/18722 0.00668752265964845 0.0553122233403314 GAPDH/GRN/AAK1/RPL23/SOX4/PLPP3/HSPA1A/GNAQ/RTN4/NPM1/CTNND1/PTGES3/PFN1 13 GO:0006983 ER overload response 3/580 13/18722 0.00670739496107222 0.0553122233403314 HSPA5/DDIT3/CCDC47 3 GO:0010958 regulation of amino acid import across plasma membrane 3/580 13/18722 0.00670739496107222 0.0553122233403314 ITGB1/SLC43A2/ARL6IP5 3 GO:0032352 positive regulation of hormone metabolic process 3/580 13/18722 0.00670739496107222 0.0553122233403314 EGR1/ADM/POR 3 GO:0044794 positive regulation by host of viral process 3/580 13/18722 0.00670739496107222 0.0553122233403314 CFL1/STOM/HSPA8 3 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 3/580 13/18722 0.00670739496107222 0.0553122233403314 CALM1/GSTO1/CALM2 3 GO:0060670 branching involved in labyrinthine layer morphogenesis 3/580 13/18722 0.00670739496107222 0.0553122233403314 SPINT1/SPINT2/ADM 3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding 3/580 13/18722 0.00670739496107222 0.0553122233403314 DDIT3/NSD1/TMSB4X 3 GO:1903789 regulation of amino acid transmembrane transport 3/580 13/18722 0.00670739496107222 0.0553122233403314 ITGB1/SLC43A2/ARL6IP5 3 GO:0034109 homotypic cell-cell adhesion 8/580 90/18722 0.00677200222569383 0.0556890190038622 PLPP3/DSG2/PPIA/DSC2/IL6ST/ACTG1/DSP/MYL12A 8 GO:0072009 nephron epithelium development 9/580 109/18722 0.00677703391876714 0.0556890190038622 LAMA5/LGR4/IQGAP1/PBX1/GLI3/TACSTD2/IRX2/MAGED1/GPC3 9 GO:0043487 regulation of RNA stability 12/580 170/18722 0.00679381148000372 0.0557284253853568 ZFP36L1/TNRC6A/YBX1/ROCK1/NPM1/PUM1/FUS/HNRNPC/HNRNPD/CIRBP/CARHSP1/SERBP1 12 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 4/580 25/18722 0.00687235576119995 0.0558447321287121 GJA5/GJA1/RHOA/CYBA 4 GO:0033119 negative regulation of RNA splicing 4/580 25/18722 0.00687235576119995 0.0558447321287121 RPS13/RPS26/NPM1/SRSF6 4 GO:0048143 astrocyte activation 4/580 25/18722 0.00687235576119995 0.0558447321287121 LRP1/EGFR/GRN/APP 4 GO:1900078 positive regulation of cellular response to insulin stimulus 4/580 25/18722 0.00687235576119995 0.0558447321287121 ESRRA/GNAI2/PRKCZ/IGF2 4 GO:1903959 regulation of anion transmembrane transport 4/580 25/18722 0.00687235576119995 0.0558447321287121 TCAF1/ITGB1/SLC43A2/ARL6IP5 4 GO:0034101 erythrocyte homeostasis 10/580 129/18722 0.00688003257573683 0.0558447321287121 RPS6/TGFBR3/UFL1/HSPA1A/RPS17/ZFP36L1/PRKDC/CITED2/CDK6/HMGB2 10 GO:0003229 ventricular cardiac muscle tissue development 6/580 55/18722 0.00689704762294392 0.0558853109657007 LRP2/TGFBR3/DSG2/ISL1/TBX3/DSP 6 GO:0048762 mesenchymal cell differentiation 15/580 236/18722 0.00696167835742988 0.0563108974615763 LAMA5/NRP2/DAG1/SEMA6A/SEMA6D/TGFBR3/ISL1/FOLR1/ROCK1/RTN4/TBX3/DLG5/CITED2/TCF7L2/BMP7 15 GO:0032872 regulation of stress-activated MAPK cascade 13/580 192/18722 0.00697713081605985 0.0563379087248166 EGFR/GADD45B/APP/DUSP1/IGF1R/HMGCR/MARVELD3/EMC10/PPIA/GADD45G/ARL6IP5/HMGB1/CDC42 13 GO:0003014 renal system process 9/580 110/18722 0.00718452821204503 0.0578118351457119 CLDN4/GJA5/GJA1/MAGED2/ADM/LGMN/GNAI2/RHOA/CYBA 9 GO:0007088 regulation of mitotic nuclear division 9/580 110/18722 0.00718452821204503 0.0578118351457119 DUSP1/LRP5/PHIP/CENPF/BMP7/TPR/IGF2/CDC42/ANAPC11 9 GO:0001657 ureteric bud development 8/580 91/18722 0.00722923830989329 0.0578712347320374 LAMA5/LGR4/PBX1/GLI3/TACSTD2/MAGED1/GPC3/BMP7 8 GO:0014033 neural crest cell differentiation 8/580 91/18722 0.00722923830989329 0.0578712347320374 LAMA5/NRP2/SEMA6A/SEMA6D/ISL1/FOLR1/CITED2/BMP7 8 GO:0072080 nephron tubule development 8/580 91/18722 0.00722923830989329 0.0578712347320374 LAMA5/LGR4/PBX1/GLI3/TACSTD2/IRX2/MAGED1/GPC3 8 GO:0042476 odontogenesis 10/580 130/18722 0.00725335063811715 0.0579644910960187 LAMA5/CSF3R/LAMB1/ANKRD11/BSG/GLI3/ADM/BMP7/TFAP2A/RHOA 10 GO:0031669 cellular response to nutrient levels 14/580 215/18722 0.00730502901780141 0.0582773412723745 JUN/ATP2B1/HSPA5/SLC2A1/SLC38A2/TNRC6A/FOLR1/HNRNPA1/CTSV/PMAIP1/EIF4G1/EIF2AK4/XBP1/HSPA8 14 GO:0090150 establishment of protein localization to membrane 16/580 260/18722 0.0073260475859293 0.0583449440447896 EGFR/TCAF1/HSPA5/GOLGA4/MACF1/SPTBN1/SIL1/EMC1/CALM1/SEC62/EMC10/VAMP2/STOM/CCDC47/SSR2/RAB11A 16 GO:0051146 striated muscle cell differentiation 17/580 283/18722 0.00733865887795821 0.0583454742587754 KRT19/ITGB1/PLEC/ISL1/SLC9A1/YBX1/TBX3/CD81/PLD3/ACTG1/KRT8/XBP1/GPX1/IGF2/CDK1/CACYBP/MORF4L2 17 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 7/580 73/18722 0.00736462861978963 0.0583524492515189 LRP1/LRP5/HMGCR/KIF5B/HMGN3/DYNLL1/PHPT1 7 GO:0042274 ribosomal small subunit biogenesis 7/580 73/18722 0.00736462861978963 0.0583524492515189 RPS21/RPS6/RPS16/RPS25/RPS17/PRKDC/NPM1 7 GO:1990138 neuron projection extension 12/580 172/18722 0.00743323954741531 0.0587959134949466 LRP1/NRP2/GOLGA4/MACF1/SEMA6A/SEMA6D/ITGB1/IQGAP1/RTN4/EIF2AK4/PRKCZ/RAB11A 12 GO:0031122 cytoplasmic microtubule organization 6/580 56/18722 0.00752751845982581 0.0590190513249239 DYNC1H1/CLIP1/DST/HOOK2/RHOA/RAB11A 6 GO:0043388 positive regulation of DNA binding 6/580 56/18722 0.00752751845982581 0.0590190513249239 ISL1/CALM1/TXN/CALM2/HMGB1/HMGB2 6 GO:0051653 spindle localization 6/580 56/18722 0.00752751845982581 0.0590190513249239 DYNC1H1/ITGB1/GJA1/ASPM/CFL1/DYNLT1 6 GO:0071385 cellular response to glucocorticoid stimulus 6/580 56/18722 0.00752751845982581 0.0590190513249239 ATP2B1/EGFR/SERPINF1/ZFP36L1/ISL1/UBE2L3 6 GO:0030501 positive regulation of bone mineralization 5/580 40/18722 0.00753758686024614 0.0590190513249239 FBN2/ATP2B1/BMP7/TFAP2A/ATRAID 5 GO:1901020 negative regulation of calcium ion transmembrane transporter activity 5/580 40/18722 0.00753758686024614 0.0590190513249239 CALM1/C4orf3/GSTO1/CALM2/YWHAE 5 GO:0050870 positive regulation of T cell activation 14/580 216/18722 0.0075969591543567 0.0593839613897698 CD46/SOX4/GLI3/DPP4/TFRC/CD81/CAV1/IL6ST/XBP1/CD55/PRKCZ/RHOA/HMGB1/IGF2 14 GO:0071214 cellular response to abiotic stimulus 19/580 331/18722 0.00762951898921426 0.0594386814385854 EGFR/DAG1/RHOB/HSPA5/EGR1/SLC2A1/PLEC/SLC38A2/ZFP36L1/GJA1/SLC9A1/DDB1/TMEM150C/NPM1/NIPBL/EIF2AK4/ADIRF/PCNA/CYBA 19 GO:0104004 cellular response to environmental stimulus 19/580 331/18722 0.00762951898921426 0.0594386814385854 EGFR/DAG1/RHOB/HSPA5/EGR1/SLC2A1/PLEC/SLC38A2/ZFP36L1/GJA1/SLC9A1/DDB1/TMEM150C/NPM1/NIPBL/EIF2AK4/ADIRF/PCNA/CYBA 19 GO:0072163 mesonephric epithelium development 8/580 92/18722 0.00770936973860199 0.0598602314761901 LAMA5/LGR4/PBX1/GLI3/TACSTD2/MAGED1/GPC3/BMP7 8 GO:0072164 mesonephric tubule development 8/580 92/18722 0.00770936973860199 0.0598602314761901 LAMA5/LGR4/PBX1/GLI3/TACSTD2/MAGED1/GPC3/BMP7 8 GO:1903039 positive regulation of leukocyte cell-cell adhesion 15/580 239/18722 0.00778274166444913 0.0603292191355882 CD46/SOX4/NFAT5/GLI3/DPP4/TFRC/CD81/CAV1/IL6ST/XBP1/CD55/PRKCZ/RHOA/HMGB1/IGF2 15 GO:0030073 insulin secretion 13/580 195/18722 0.00790599674516177 0.0608345585253964 LRP1/SOX4/ISL1/LRP5/GJA1/DPP4/HMGCR/KIF5B/TCF7L2/HMGN3/DYNLL1/FAM3B/PHPT1 13 GO:0070302 regulation of stress-activated protein kinase signaling cascade 13/580 195/18722 0.00790599674516177 0.0608345585253964 EGFR/GADD45B/APP/DUSP1/IGF1R/HMGCR/MARVELD3/EMC10/PPIA/GADD45G/ARL6IP5/HMGB1/CDC42 13 GO:0048844 artery morphogenesis 7/580 74/18722 0.00792288533122033 0.0608345585253964 LRP2/LRP1/SOX4/GJA5/FOLR1/CITED2/HPGD 7 GO:0070972 protein localization to endoplasmic reticulum 7/580 74/18722 0.00792288533122033 0.0608345585253964 HSPA5/GPAA1/GJA1/PPP1R15A/RTN4/OS9/SEC62 7 GO:0006027 glycosaminoglycan catabolic process 4/580 26/18722 0.00792641205469582 0.0608345585253964 NAGLU/GUSB/GNS/FUCA1 4 GO:0032515 negative regulation of phosphoprotein phosphatase activity 4/580 26/18722 0.00792641205469582 0.0608345585253964 BOD1L1/PPP1R15A/ROCK1/GNAI2 4 GO:0007584 response to nutrient 12/580 174/18722 0.0081190166842784 0.0622101261920574 ATP2B1/EGFR/LDHA/FOLR1/HMGCR/POR/SLC6A4/BMP7/XBP1/AGL/GNAI2/TYMS 12 GO:0033619 membrane protein proteolysis 6/580 57/18722 0.00819851174039315 0.0626129361322964 DAG1/NCSTN/ROCK1/SPPL2A/TIMP3/HM13 6 GO:1900024 regulation of substrate adhesion-dependent cell spreading 6/580 57/18722 0.00819851174039315 0.0626129361322964 FBLN1/P4HB/KANK1/TACSTD2/TRIOBP/CDC42 6 GO:0060349 bone morphogenesis 8/580 93/18722 0.00821308583676445 0.0626214134865434 GLG1/SERPINH1/LRP5/GLI3/TRIP11/POR/CITED2/TFAP2A 8 GO:0090276 regulation of peptide hormone secretion 13/580 196/18722 0.00823639783658134 0.0626963769851716 LRP1/EGFR/SOX4/ISL1/LRP5/GJA1/DPP4/HMGCR/KIF5B/TCF7L2/HMGN3/DYNLL1/PHPT1 13 GO:0010771 negative regulation of cell morphogenesis involved in differentiation 3/580 14/18722 0.00834243718252102 0.063090529001472 FBLN1/KANK1/TACSTD2 3 GO:0043558 regulation of translational initiation in response to stress 3/580 14/18722 0.00834243718252102 0.063090529001472 PPP1R15A/NPM1/EIF2AK4 3 GO:0071236 cellular response to antibiotic 3/580 14/18722 0.00834243718252102 0.063090529001472 HSPA5/RPL23/SLC9A1 3 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading 3/580 14/18722 0.00834243718252102 0.063090529001472 FBLN1/KANK1/TACSTD2 3 GO:0042307 positive regulation of protein import into nucleus 5/580 41/18722 0.00837069130112554 0.0630990036329577 CDH1/GLI3/TPR/RAN/CDK1 5 GO:0071634 regulation of transforming growth factor beta production 5/580 41/18722 0.00837069130112554 0.0630990036329577 ITGAV/LTBP1/CD46/FERMT1/ATP6AP2 5 GO:0022900 electron transport chain 12/580 175/18722 0.00847997287652595 0.0638193427972851 COX6A1/PLEC/GLDC/POR/ASPH/NDUFB9/DEGS1/UQCRH/COX8C/DHRS2/CDK1/CYBA 12 GO:0008088 axo-dendritic transport 7/580 75/18722 0.00851173279031866 0.0639548775569823 ARMCX3/DYNC1H1/APP/DST/PURA/KIF5B/HSPA8 7 GO:0097191 extrinsic apoptotic signaling pathway 14/580 219/18722 0.00852870865223657 0.0639790708734714 ITGAV/ITGA6/HSPA1A/ERBB3/PDIA3/PHIP/PMAIP1/TCF7L2/CAV1/KRT8/TIMP3/SIAH2/GPX1/HMGB2 14 GO:0042594 response to starvation 13/580 197/18722 0.00857757520286724 0.0642420326385435 JUN/HSPA5/SLC2A1/SLC38A2/TNRC6A/HNRNPA1/DDIT3/ADM/CTSV/PMAIP1/EIF2AK4/XBP1/HSPA8 13 GO:0097193 intrinsic apoptotic signaling pathway 17/580 288/18722 0.00866270429917965 0.0647753017612292 TPT1/P4HB/HSPA1A/ENO1/ERP29/DDIT3/PRKDC/PPP1R15A/PMAIP1/SIAH1/PPIA/CAV1/MIF/XBP1/S100A9/ARL6IP5/GPX1 17 GO:0001738 morphogenesis of a polarized epithelium 8/580 94/18722 0.00874107667086052 0.0649436862558662 LAMA5/ZNRF3/FAT1/DLG5/GPC3/ACTG1/RHOA/CDC42 8 GO:0030316 osteoclast differentiation 8/580 94/18722 0.00874107667086052 0.0649436862558662 FBN1/FOS/ESRRA/ATP6AP1/TFRC/GPC3/CD81/JUNB 8 GO:0051702 biological process involved in interaction with symbiont 8/580 94/18722 0.00874107667086052 0.0649436862558662 GAPDH/JUN/DDB1/EIF2AK4/CFL1/STOM/HSPA8/GPX1 8 GO:1990830 cellular response to leukemia inhibitory factor 8/580 94/18722 0.00874107667086052 0.0649436862558662 NRP2/RPS16/TLE4/TFRC/ARID5B/NCL/SRSF3/CACYBP 8 GO:0010634 positive regulation of epithelial cell migration 12/580 176/18722 0.00885334385479645 0.0653990215071223 NRP2/GRN/RHOB/MET/PLPP3/RTN4/EMC10/TMSB4X/LGMN/PFN1/HMGB1/RAB11A 12 GO:0002064 epithelial cell development 14/580 220/18722 0.00885860751440272 0.0653990215071223 ADAMTSL4/PLEC/MET/SPINT2/IQGAP1/FAT1/ROCK1/ATRX/CDK6/IL6ST/TRIOBP/E2F4/TYMS/GPX1 14 GO:0031503 protein-containing complex localization 14/580 220/18722 0.00885860751440272 0.0653990215071223 AKAP9/DAG1/PABPN1/PURA/KIF5B/NPM1/VAMP2/THOC2/TPR/PRKCZ/HNRNPA2B1/RAN/SRSF3/RAB11A 14 GO:0048705 skeletal system morphogenesis 14/580 220/18722 0.00885860751440272 0.0653990215071223 FBN2/GLG1/ANKRD11/SERPINH1/LRP5/GLI3/TRIP11/POR/CITED2/NIPBL/BMP7/ARID5B/TFAP2A/SLC39A1 14 GO:0043525 positive regulation of neuron apoptotic process 6/580 58/18722 0.00891140459621997 0.0655806056598403 JUN/GRN/DDIT3/TFAP2A/RHOA/CDC42 6 GO:2000649 regulation of sodium ion transmembrane transporter activity 6/580 58/18722 0.00891140459621997 0.0655806056598403 UTRN/SLC9A1/KIF5B/STOM/FXYD3/YWHAH 6 GO:0007519 skeletal muscle tissue development 11/580 155/18722 0.00898562102443082 0.0660223118240565 FOS/EGR1/PLEC/GPC1/HMGCR/CITED2/NR2F2/CAV1/GPX1/RHOA/IGF2 11 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 4/580 27/18722 0.00908124406012776 0.0665147498010302 SLC9A1/CALM1/GSTO1/CALM2 4 GO:0033688 regulation of osteoblast proliferation 4/580 27/18722 0.00908124406012776 0.0665147498010302 ITGAV/LRP5/ATRAID/RHOA 4 GO:0071426 ribonucleoprotein complex export from nucleus 7/580 76/18722 0.00913211635684083 0.0666773519241236 PABPN1/NPM1/THOC2/TPR/HNRNPA2B1/RAN/SRSF3 7 GO:0140115 export across plasma membrane 7/580 76/18722 0.00913211635684083 0.0666773519241236 ATP2B1/GJA1/SLC9A1/CALM1/SLC40A1/CALM2/YWHAE 7 GO:0008406 gonad development 14/580 221/18722 0.00919849883264079 0.0670195789262556 LRP2/HSPA5/ADGRG1/SF1/ADAMTS1/CTSV/ATRX/KDM5A/CITED2/NR2F2/ASPM/ARID5B/EIF2S2/HMGB2 14 GO:0098739 import across plasma membrane 12/580 177/18722 0.00923940882894203 0.0670195789262556 LRP2/SLC39A10/ITGB1/SLC3A2/SLC2A1/SLC1A5/SLC12A9/SLC43A2/FOLR1/SLC9A1/SLC19A1/ARL6IP5 12 GO:0034504 protein localization to nucleus 17/580 290/18722 0.00924312405844294 0.0670195789262556 CDH1/RPL23/PPP1R10/GLI3/FERMT1/TFRC/MAGED1/NPM1/BMP7/TPR/TXN/TRIM29/NFKBIA/RAN/YWHAE/TXNIP/CDK1 17 GO:0021795 cerebral cortex cell migration 5/580 42/18722 0.00926544597926948 0.0670195789262556 LAMB1/ADGRG1/GLI3/RTN4/RHOA 5 GO:0045214 sarcomere organization 5/580 42/18722 0.00926544597926948 0.0670195789262556 KRT19/ITGB1/PLEC/ACTG1/KRT8 5 GO:0072595 maintenance of protein localization in organelle 5/580 42/18722 0.00926544597926948 0.0670195789262556 HSPA5/GPAA1/GJA1/OS9/TXN 5 GO:1990823 response to leukemia inhibitory factor 8/580 95/18722 0.00929403232224755 0.0671219632465424 NRP2/RPS16/TLE4/TFRC/ARID5B/NCL/SRSF3/CACYBP 8 GO:0009267 cellular response to starvation 11/580 156/18722 0.00940647361964375 0.0678286958216482 JUN/HSPA5/SLC2A1/SLC38A2/TNRC6A/HNRNPA1/CTSV/PMAIP1/EIF2AK4/XBP1/HSPA8 11 GO:0030278 regulation of ossification 9/580 115/18722 0.00950965427879099 0.0684665666418837 FBN2/ATP2B1/ESRRA/PBX1/NOTUM/NIPBL/BMP7/TFAP2A/ATRAID 9 GO:0015931 nucleobase-containing compound transport 14/580 222/18722 0.00954858519106131 0.068640602354909 ZFP36L1/GJA1/HNRNPA1/YBX1/PABPN1/SLC19A1/SLC25A36/NPM1/THOC2/TPR/HNRNPA2B1/HNRNPA3/RAN/SRSF3 14 GO:0009100 glycoprotein metabolic process 21/580 387/18722 0.00959114006523026 0.0688401117953487 GANAB/CTSL/CHPF/RPN2/NCSTN/EXTL2/GPC1/MANBA/CHST12/B3GAT3/DDOST/TRIP11/C1GALT1/GALNT11/MAN1A2/TCF7L2/MGAT1/MPDU1/ITM2B/TMEM59/TUSC3 21 GO:0017148 negative regulation of translation 15/580 245/18722 0.00965595775195386 0.0690728121944702 GAPDH/RPL13A/ZFP36L1/TNRC6A/YBX1/PURA/ROCK1/PUM1/EIF4G1/EIF2AK4/TPR/TYMS/HNRNPD/CIRBP/NCL 15 GO:0006767 water-soluble vitamin metabolic process 6/580 59/18722 0.00966755855034676 0.0690728121944702 SLC2A1/SLC52A1/FOLR1/SLC52A2/SLC19A1/GSTO1 6 GO:0002791 regulation of peptide secretion 13/580 200/18722 0.00966811454280802 0.0690728121944702 LRP1/EGFR/SOX4/ISL1/LRP5/GJA1/DPP4/HMGCR/KIF5B/TCF7L2/HMGN3/DYNLL1/PHPT1 13 GO:0031016 pancreas development 7/580 77/18722 0.00978497687616279 0.0695722101208405 MET/WLS/SOX4/ISL1/TCF7L2/CDK6/IGF2 7 GO:0071166 ribonucleoprotein complex localization 7/580 77/18722 0.00978497687616279 0.0695722101208405 PABPN1/NPM1/THOC2/TPR/HNRNPA2B1/RAN/SRSF3 7 GO:0045727 positive regulation of translation 10/580 136/18722 0.00983258739876941 0.0695722101208405 SOX4/PRKDC/PPP1R15A/NPM1/EIF4G1/EIF2AK4/PKM/HNRNPD/RHOA/CIRBP 10 GO:0072073 kidney epithelium development 10/580 136/18722 0.00983258739876941 0.0695722101208405 LAMA5/LGR4/IQGAP1/PBX1/GLI3/TACSTD2/IRX2/MAGED1/GPC3/BMP7 10 GO:1900180 regulation of protein localization to nucleus 10/580 136/18722 0.00983258739876941 0.0695722101208405 CDH1/GLI3/FERMT1/TFRC/MAGED1/NPM1/TPR/TRIM29/RAN/CDK1 10 GO:1990845 adaptive thermogenesis 11/580 157/18722 0.00984237026100147 0.0695722101208405 DYNC1H1/LGR4/GJA1/ADRB1/DDIT3/IGF1R/PRLR/CAV1/ID1/GADD45G/PLAC8 11 GO:0001823 mesonephros development 8/580 96/18722 0.00987264215862282 0.0695722101208405 LAMA5/LGR4/PBX1/GLI3/TACSTD2/MAGED1/GPC3/BMP7 8 GO:0010769 regulation of cell morphogenesis involved in differentiation 8/580 96/18722 0.00987264215862282 0.0695722101208405 FBLN1/P4HB/KANK1/PRKDC/TACSTD2/CUX1/TRIOBP/CDC42 8 GO:0034620 cellular response to unfolded protein 8/580 96/18722 0.00987264215862282 0.0695722101208405 HSPA5/UFL1/HSPA1A/DDIT3/PPP1R15A/OS9/XBP1/HSPA8 8 GO:0008286 insulin receptor signaling pathway 9/580 116/18722 0.0100358907826645 0.070402606380351 KANK1/SLC2A8/IGF1R/PHIP/PTPRA/GNAI2/CCND3/PRKCZ/IGF2 9 GO:0018107 peptidyl-threonine phosphorylation 9/580 116/18722 0.0100358907826645 0.070402606380351 APP/PRKDC/ROCK1/CALM1/EIF4G1/BMP7/CALM2/CDK1/CSNK2B 9 GO:0035967 cellular response to topologically incorrect protein 9/580 116/18722 0.0100358907826645 0.070402606380351 HSPA5/UFL1/HSPA1A/DDIT3/PPP1R15A/OS9/DNAJB14/XBP1/HSPA8 9 GO:0009263 deoxyribonucleotide biosynthetic process 3/580 15/18722 0.010191153004804 0.0706561139024925 DUT/TYMS/RRM2 3 GO:0045475 locomotor rhythm 3/580 15/18722 0.010191153004804 0.0706561139024925 EGR1/NAGLU/ZFHX3 3 GO:0048569 post-embryonic animal organ development 3/580 15/18722 0.010191153004804 0.0706561139024925 FBN1/LDHA/EFEMP1 3 GO:0051284 positive regulation of sequestering of calcium ion 3/580 15/18722 0.010191153004804 0.0706561139024925 CALM1/GSTO1/CALM2 3 GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response 3/580 15/18722 0.010191153004804 0.0706561139024925 HSPA5/UFL1/PPP1R15A 3 GO:2001028 positive regulation of endothelial cell chemotaxis 3/580 15/18722 0.010191153004804 0.0706561139024925 MET/TMSB4X/LGMN 3 GO:0006509 membrane protein ectodomain proteolysis 5/580 43/18722 0.0102239442391695 0.0706561139024925 DAG1/NCSTN/ROCK1/SPPL2A/TIMP3 5 GO:0061383 trabecula morphogenesis 5/580 43/18722 0.0102239442391695 0.0706561139024925 FBN2/TGFBR3/ADAMTS1/BMP7/RHOA 5 GO:0071604 transforming growth factor beta production 5/580 43/18722 0.0102239442391695 0.0706561139024925 ITGAV/LTBP1/CD46/FERMT1/ATP6AP2 5 GO:1904591 positive regulation of protein import 5/580 43/18722 0.0102239442391695 0.0706561139024925 CDH1/GLI3/TPR/RAN/CDK1 5 GO:2001234 negative regulation of apoptotic signaling pathway 14/580 224/18722 0.0102801588570938 0.0709334646023673 TPT1/ITGAV/ITGA6/HSPA1A/ENO1/PHIP/TCF7L2/PPIA/MIF/XBP1/SIAH2/GNAI2/GPX1/HMGB2 14 GO:0032801 receptor catabolic process 4/580 28/18722 0.0103404016554593 0.0709334646023673 RNF43/ZNRF3/MYLIP/LGMN 4 GO:0090344 negative regulation of cell aging 4/580 28/18722 0.0103404016554593 0.0709334646023673 YBX1/PRKDC/CDK6/MIF 4 GO:1990776 response to angiotensin 4/580 28/18722 0.0103404016554593 0.0709334646023673 IQGAP1/ROCK1/CAV1/CYBA 4 GO:1901987 regulation of cell cycle phase transition 21/580 390/18722 0.0104050902049644 0.0709334646023673 EGFR/APP/DUSP1/SOX4/ZFP36L1/PPP1R10/ADAMTS1/PBX1/DDB1/PRKDC/NPM1/CENPF/BRD4/EIF4G1/EIF2AK4/TPR/CTDSPL/CCND3/CDK1/ANAPC11/RAB11A 21 GO:0090087 regulation of peptide transport 13/580 202/18722 0.0104533520474577 0.0709334646023673 LRP1/EGFR/SOX4/ISL1/LRP5/GJA1/DPP4/HMGCR/KIF5B/TCF7L2/HMGN3/DYNLL1/PHPT1 13 GO:0042306 regulation of protein import into nucleus 6/580 60/18722 0.0104683170958704 0.0709334646023673 CDH1/GLI3/FERMT1/TPR/RAN/CDK1 6 GO:0043297 apical junction assembly 7/580 78/18722 0.0104712494021199 0.0709334646023673 CLDN4/GJA1/ROCK1/DLG5/PKN2/MARVELD3/RHOA 7 GO:0070373 negative regulation of ERK1 and ERK2 cascade 7/580 78/18722 0.0104712494021199 0.0709334646023673 FBLN1/SEMA6A/DUSP1/DUSP6/EIF3A/DUSP9/TIMP3 7 GO:0048660 regulation of smooth muscle cell proliferation 12/580 180/18722 0.0104765798280616 0.0709334646023673 JUN/EGFR/SF1/ADAMTS1/GJA1/PRKDC/HMGCR/TCF7L2/GNAI2/RHOA/HPGD/CYBA 12 GO:0070252 actin-mediated cell contraction 8/580 97/18722 0.0104775941048863 0.0709334646023673 AKAP9/DSG2/GJA5/GJA1/SLC9A1/DSC2/CAV1/DSP 8 GO:0120162 positive regulation of cold-induced thermogenesis 8/580 97/18722 0.0104775941048863 0.0709334646023673 DYNC1H1/GJA1/ADRB1/IGF1R/PRLR/CAV1/GADD45G/PLAC8 8 GO:1901216 positive regulation of neuron death 8/580 97/18722 0.0104775941048863 0.0709334646023673 JUN/FOS/GRN/EGR1/DDIT3/TFAP2A/RHOA/CDC42 8 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 8/580 97/18722 0.0104775941048863 0.0709334646023673 ITGAV/ITGA6/HSPA1A/PHIP/TCF7L2/SIAH2/GPX1/HMGB2 8 GO:0051604 protein maturation 17/580 294/18722 0.0104970178741891 0.0709616717047291 GLG1/CTSL/SOX4/NCSTN/ENO1/ENPEP/DHCR24/SERPINH1/LMF2/GLI3/ATP6AP2/ASPH/PISD/TMEM59/LGMN/TMEM208/HM13 17 GO:1903828 negative regulation of cellular protein localization 9/580 117/18722 0.0105837618100779 0.0713467421092819 LMAN1/FERMT1/OS9/MAGED1/HECTD1/TXN/TMEM59/TRIM29/LEPROT 9 GO:0015980 energy derivation by oxidation of organic compounds 18/580 318/18722 0.0105846596549999 0.0713467421092819 COX6A1/GAA/PLEC/IL10RB/IL6ST/NDUFB9/AGL/ACADVL/PHLDA2/PTGES3/RHOA/HMGB1/UQCRH/IGF2/COX8C/PYGL/CDK1/UGP2 18 GO:0016485 protein processing 14/580 225/18722 0.0106620566039646 0.0716607301517913 GLG1/CTSL/NCSTN/ENO1/ENPEP/DHCR24/GLI3/ATP6AP2/ASPH/PISD/TMEM59/LGMN/TMEM208/HM13 14 GO:0050769 positive regulation of neurogenesis 14/580 225/18722 0.0106620566039646 0.0716607301517913 LRP2/LRP1/EGFR/SPINT1/DAG1/GOLGA4/MACF1/SERPINF1/UFL1/GLI3/CUX1/ASPM/IL6ST/RAB11A 14 GO:0051170 import into nucleus 11/580 159/18722 0.0107606571556514 0.07221907132891 CDH1/RPL23/PPP1R10/HNRNPA1/GLI3/FERMT1/TPR/NFKBIA/RAN/TXNIP/CDK1 11 GO:0008361 regulation of cell size 12/580 181/18722 0.0109162386015827 0.0729474507700589 LRP1/GOLGA4/MACF1/SEMA6A/SEMA6D/KCNN4/SLC12A9/RTN4/NPM1/E2F4/RHOA/RAB11A 12 GO:0045766 positive regulation of angiogenesis 12/580 181/18722 0.0109162386015827 0.0729474507700589 GRN/RHOB/ITGB1/ISL1/BTG1/ADM/EMC10/PKM/XBP1/MYDGF/NINJ1/HMGB1 12 GO:1904018 positive regulation of vasculature development 12/580 181/18722 0.0109162386015827 0.0729474507700589 GRN/RHOB/ITGB1/ISL1/BTG1/ADM/EMC10/PKM/XBP1/MYDGF/NINJ1/HMGB1 12 GO:0051962 positive regulation of nervous system development 16/580 272/18722 0.0110069889859853 0.0734483583555491 LRP2/LRP1/EGFR/SPINT1/DAG1/GOLGA4/MACF1/SERPINF1/UFL1/TPBG/GLI3/DLG5/CUX1/ASPM/IL6ST/RAB11A 16 GO:0022612 gland morphogenesis 9/580 118/18722 0.0111537949296544 0.0738918961202449 LAMA5/DAG1/LRP5/GLI3/TBX3/BMP7/CAV1/XBP1/CDC42 9 GO:0030203 glycosaminoglycan metabolic process 9/580 118/18722 0.0111537949296544 0.0738918961202449 ITIH5/CHPF/NAGLU/HEXA/GUSB/CHST12/B3GAT3/GNS/FUCA1 9 GO:1903313 positive regulation of mRNA metabolic process 9/580 118/18722 0.0111537949296544 0.0738918961202449 ZFP36L1/TNRC6A/ROCK1/PUM1/TRA2B/HSPA8/HNRNPD/CIRBP/NCL 9 GO:0050890 cognition 17/580 296/18722 0.0111727041310736 0.0738918961202449 JUN/FOS/EGFR/APP/ITGB1/SERPINF1/NCSTN/TPBG/HMGCR/SLC6A4/NIPBL/EIF2AK4/LGMN/TUSC3/ARL6IP5/PRKCZ/VDAC1 17 GO:0051258 protein polymerization 17/580 296/18722 0.0111727041310736 0.0738918961202449 AKAP9/IQGAP2/CLIP1/KANK1/MET/HSPA1A/SPTAN1/SPTBN1/DIAPH1/TMSB4X/WASF2/TRIOBP/MSRB2/PFN1/RASA1/RHOA/STMN1 17 GO:0032272 negative regulation of protein polymerization 7/580 79/18722 0.0111918619343707 0.0738918961202449 KANK1/SPTAN1/SPTBN1/TMSB4X/TRIOBP/PFN1/STMN1 7 GO:0060420 regulation of heart growth 7/580 79/18722 0.0111918619343707 0.0738918961202449 TGFBR3/DUSP6/GJA1/DUSP9/CITED2/VGLL4/CDK1 7 GO:0043271 negative regulation of ion transport 11/580 160/18722 0.0112437303525364 0.0738918961202449 GABRE/SLC43A2/CALM1/C4orf3/GSTO1/CAV1/ARL6IP5/CALM2/VDAC1/YWHAE/YWHAQ 11 GO:0048806 genitalia development 5/580 44/18722 0.0112482181150577 0.0738918961202449 LRP2/LGR4/DHCR24/TBX3/NIPBL 5 GO:0089718 amino acid import across plasma membrane 5/580 44/18722 0.0112482181150577 0.0738918961202449 ITGB1/SLC3A2/SLC1A5/SLC43A2/ARL6IP5 5 GO:1903573 negative regulation of response to endoplasmic reticulum stress 5/580 44/18722 0.0112482181150577 0.0738918961202449 HSPA5/UFL1/HSPA1A/PPP1R15A/XBP1 5 GO:0040014 regulation of multicellular organism growth 6/580 61/18722 0.0113150033462829 0.0741212402303685 APP/ADRB1/NIPBL/LGMN/PLAC8/IGF2 6 GO:0071384 cellular response to corticosteroid stimulus 6/580 61/18722 0.0113150033462829 0.0741212402303685 ATP2B1/EGFR/SERPINF1/ZFP36L1/ISL1/UBE2L3 6 GO:0045137 development of primary sexual characteristics 14/580 227/18722 0.011459106804815 0.0749596424039308 LRP2/HSPA5/ADGRG1/SF1/ADAMTS1/CTSV/ATRX/KDM5A/CITED2/NR2F2/ASPM/ARID5B/EIF2S2/HMGB2 14 GO:0021522 spinal cord motor neuron differentiation 4/580 29/18722 0.0117072053031368 0.0763677585762824 SOX4/ISL1/GLI3/LMO4 4 GO:0021602 cranial nerve morphogenesis 4/580 29/18722 0.0117072053031368 0.0763677585762824 NRP2/GLI3/CITED2/TFAP2A 4 GO:0007159 leukocyte cell-cell adhesion 20/580 371/18722 0.0120737483352062 0.078228260029287 CD46/ITGB1/SOX4/NFAT5/GLI3/DPP4/ROCK1/DLG5/TFRC/CD81/BMP7/CAV1/IL6ST/XBP1/CD55/S100A9/PRKCZ/RHOA/HMGB1/IGF2 20 GO:0048863 stem cell differentiation 13/580 206/18722 0.0121721682077218 0.078228260029287 LAMA5/NRP2/SEMA6A/SEMA6D/UFL1/ISL1/FOLR1/N4BP2L2/PRKDC/TACSTD2/CITED2/PUM1/BMP7 13 GO:0060135 maternal process involved in female pregnancy 6/580 62/18722 0.0122089177618362 0.078228260029287 BSG/GJA1/CTSV/CITED2/NR2F2/JUNB 6 GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 6/580 62/18722 0.0122089177618362 0.078228260029287 DAG1/VAMP2/CTNND1/PRKCZ/YWHAE/RAB11A 6 GO:1903078 positive regulation of protein localization to plasma membrane 6/580 62/18722 0.0122089177618362 0.078228260029287 LRP1/EGFR/ITGB1/SPTBN1/KIF5B/RAB11A 6 GO:0001732 formation of cytoplasmic translation initiation complex 3/580 16/18722 0.0122584921245488 0.078228260029287 EIF3A/EIF2S2/EIF3H 3 GO:0001977 renal system process involved in regulation of blood volume 3/580 16/18722 0.0122584921245488 0.078228260029287 GJA5/GJA1/CYBA 3 GO:0003084 positive regulation of systemic arterial blood pressure 3/580 16/18722 0.0122584921245488 0.078228260029287 NR2F2/RHOA/CYBA 3 GO:0017014 protein nitrosylation 3/580 16/18722 0.0122584921245488 0.078228260029287 GAPDH/TXN/S100A9 3 GO:0018119 peptidyl-cysteine S-nitrosylation 3/580 16/18722 0.0122584921245488 0.078228260029287 GAPDH/TXN/S100A9 3 GO:0019377 glycolipid catabolic process 3/580 16/18722 0.0122584921245488 0.078228260029287 HEXA/FUCA1/NEU1 3 GO:0033631 cell-cell adhesion mediated by integrin 3/580 16/18722 0.0122584921245488 0.078228260029287 ITGB1/PLPP3/DPP4 3 GO:0061684 chaperone-mediated autophagy 3/580 16/18722 0.0122584921245488 0.078228260029287 EEF1A1/CTSA/HSPA8 3 GO:0051100 negative regulation of binding 11/580 162/18722 0.0122594481198265 0.078228260029287 JUN/LRPAP1/PTPRF/DDIT3/ROCK1/RSF1/C4orf3/CAV1/TMSB4X/ID1/NFKBIA 11 GO:0051494 negative regulation of cytoskeleton organization 11/580 162/18722 0.0122594481198265 0.078228260029287 KANK1/MET/SPTAN1/SPTBN1/TACSTD2/NPM1/TMSB4X/WASF2/TRIOBP/PFN1/STMN1 11 GO:0048659 smooth muscle cell proliferation 12/580 184/18722 0.0123210061446289 0.078228260029287 JUN/EGFR/SF1/ADAMTS1/GJA1/PRKDC/HMGCR/TCF7L2/GNAI2/RHOA/HPGD/CYBA 12 GO:0035305 negative regulation of dephosphorylation 5/580 45/18722 0.0123402340146575 0.078228260029287 BOD1L1/PPP1R15A/ROCK1/GNAI2/YWHAE 5 GO:0035307 positive regulation of protein dephosphorylation 5/580 45/18722 0.0123402340146575 0.078228260029287 SLC39A10/PPP1R15A/CALM1/PPIA/CALM2 5 GO:0035987 endodermal cell differentiation 5/580 45/18722 0.0123402340146575 0.078228260029287 COL4A2/LAMB1/ITGAV/ITGB5/MMP15 5 GO:1904646 cellular response to amyloid-beta 5/580 45/18722 0.0123402340146575 0.078228260029287 LRP1/APP/GJA1/IGF1R/LGMN 5 GO:0030218 erythrocyte differentiation 9/580 120/18722 0.0123624534769998 0.078228260029287 RPS6/TGFBR3/UFL1/HSPA1A/ZFP36L1/PRKDC/CITED2/CDK6/HMGB2 9 GO:0048675 axon extension 9/580 120/18722 0.0123624534769998 0.078228260029287 LRP1/NRP2/GOLGA4/MACF1/SEMA6A/SEMA6D/ITGB1/RTN4/RAB11A 9 GO:0006096 glycolytic process 7/580 81/18722 0.0127397762905847 0.0801795663430439 GAPDH/LDHA/APP/ALDOA/ENO1/TPI1/PKM 7 GO:0048708 astrocyte differentiation 7/580 81/18722 0.0127397762905847 0.0801795663430439 LRP1/EGFR/GRN/APP/CDK6/IL6ST/S100A9 7 GO:0051817 modulation of process of other organism involved in symbiotic interaction 7/580 81/18722 0.0127397762905847 0.0801795663430439 JUN/DAG1/EIF2AK4/CFL1/STOM/HSPA8/SERPINB9 7 GO:0060968 regulation of gene silencing 7/580 81/18722 0.0127397762905847 0.0801795663430439 NEAT1/EGFR/KCNQ1OT1/PUM1/EIF4G1/TPR/MPHOSPH8 7 GO:0050657 nucleic acid transport 11/580 163/18722 0.0127927783922532 0.0802958330666254 ZFP36L1/HNRNPA1/YBX1/PABPN1/NPM1/THOC2/TPR/HNRNPA2B1/HNRNPA3/RAN/SRSF3 11 GO:0050658 RNA transport 11/580 163/18722 0.0127927783922532 0.0802958330666254 ZFP36L1/HNRNPA1/YBX1/PABPN1/NPM1/THOC2/TPR/HNRNPA2B1/HNRNPA3/RAN/SRSF3 11 GO:0046034 ATP metabolic process 16/580 277/18722 0.0129161956549348 0.0809612210122667 GAPDH/COX6A1/LDHA/APP/ALDOA/HSPA1A/ENO1/TPI1/TMSB4X/PKM/NDUFB9/HSPA8/RHOA/UQCRH/COX8C/CDK1 16 GO:0042177 negative regulation of protein catabolic process 9/580 121/18722 0.0130021284439578 0.0813292196059123 EGFR/RPL23/MYCBP2/CTSA/ROCK1/HMGCR/TIMP3/EIF3H/ATRAID 9 GO:0050729 positive regulation of inflammatory response 10/580 142/18722 0.0130584732972767 0.0813292196059123 NEAT1/EGFR/GRN/APP/CTSC/CD81/IL6ST/NINJ1/NFKBIA/S100A9 10 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 6/580 63/18722 0.0131513359557599 0.0813292196059123 HSPA1A/ERP29/DDIT3/PPP1R15A/PMAIP1/XBP1 6 GO:0098869 cellular oxidant detoxification 8/580 101/18722 0.0131744902563394 0.0813292196059123 MGST3/SOD3/BMP7/GSTO1/TXN/GPX3/S100A9/GPX1 8 GO:0006884 cell volume homeostasis 4/580 30/18722 0.0131847412562584 0.0813292196059123 KCNN4/SLC12A9/NPM1/E2F4 4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation 4/580 30/18722 0.0131847412562584 0.0813292196059123 APP/CALM1/BMP7/CALM2 4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 4/580 30/18722 0.0131847412562584 0.0813292196059123 CTSL/CTSD/CTSV/LGMN 4 GO:0044788 modulation by host of viral process 4/580 30/18722 0.0131847412562584 0.0813292196059123 EIF2AK4/CFL1/STOM/HSPA8 4 GO:0045070 positive regulation of viral genome replication 4/580 30/18722 0.0131847412562584 0.0813292196059123 DDB1/HACD3/PKN2/PPIA 4 GO:0046825 regulation of protein export from nucleus 4/580 30/18722 0.0131847412562584 0.0813292196059123 TCF7L2/TPR/TXN/YWHAE 4 GO:0140058 neuron projection arborization 4/580 30/18722 0.0131847412562584 0.0813292196059123 LRP2/MACF1/TPBG/ROCK1 4 GO:1900101 regulation of endoplasmic reticulum unfolded protein response 4/580 30/18722 0.0131847412562584 0.0813292196059123 HSPA5/UFL1/PPP1R15A/XBP1 4 GO:0031349 positive regulation of defense response 16/580 278/18722 0.0133273914561567 0.0820910529712515 NEAT1/EGFR/GRN/APP/CADM1/CTSC/GJA1/PRKDC/CD81/IL6ST/NINJ1/NFKBIA/S100A9/HMGB1/HMGB2/CYBA 16 GO:0050680 negative regulation of epithelial cell proliferation 11/580 164/18722 0.0133435467740843 0.0820910529712515 TGFBR3/SERPINF1/ISL1/GJA1/MAGED1/GPC3/NR2F2/MARVELD3/CDK6/CAV1/CDKN1C 11 GO:0007611 learning or memory 15/580 255/18722 0.0135518625137968 0.0829289051680444 JUN/FOS/EGFR/APP/ITGB1/SERPINF1/NCSTN/TPBG/HMGCR/SLC6A4/EIF2AK4/LGMN/ARL6IP5/PRKCZ/VDAC1 15 GO:0051924 regulation of calcium ion transport 15/580 255/18722 0.0135518625137968 0.0829289051680444 ATP2B1/AHNAK/GJA1/SLC9A1/DIAPH1/CALM1/C4orf3/GSTO1/CAV1/GNAI2/CALM2/RHOA/VDAC1/YWHAE/CYBA 15 GO:1903362 regulation of cellular protein catabolic process 15/580 255/18722 0.0135518625137968 0.0829289051680444 LRP2/LRP1/UFL1/RPL23/HSPA1A/CTSC/TMEM259/HECTD1/CD81/VGLL4/CAV1/MYLIP/EIF3H/ATRAID/GPX1 15 GO:0006757 ATP generation from ADP 7/580 82/18722 0.0135688877301401 0.0829289051680444 GAPDH/LDHA/APP/ALDOA/ENO1/TPI1/PKM 7 GO:2001252 positive regulation of chromosome organization 7/580 82/18722 0.0135688877301401 0.0829289051680444 PPP1R10/HNRNPA1/ATRX/TPR/MPHOSPH8/HNRNPD/HNRNPA2B1 7 GO:0006865 amino acid transport 10/580 143/18722 0.0136653384293778 0.083299461382747 ITGB1/SLC3A2/SLC38A2/SLC38A10/SLC1A5/GJA1/SLC43A2/SLC38A1/SLC38A9/ARL6IP5 10 GO:0034763 negative regulation of transmembrane transport 10/580 143/18722 0.0136653384293778 0.083299461382747 SLC43A2/CALM1/C4orf3/GSTO1/CAV1/ARL6IP5/CALM2/VDAC1/YWHAE/YWHAQ 10 GO:1904063 negative regulation of cation transmembrane transport 8/580 102/18722 0.0139213702729422 0.0847490747898617 SLC43A2/CALM1/C4orf3/GSTO1/CAV1/CALM2/VDAC1/YWHAE 8 GO:0045637 regulation of myeloid cell differentiation 13/580 210/18722 0.0141016971479596 0.0856529285428473 FBN1/JUN/FOS/CSF3R/HSPA1A/ZFP36L1/ESRRA/ATP6AP1/PRKDC/CDK6/NFKBIA/HMGB1/HMGB2 13 GO:0030837 negative regulation of actin filament polymerization 6/580 64/18722 0.0141435065837254 0.0856529285428473 KANK1/SPTAN1/SPTBN1/TMSB4X/TRIOBP/PFN1 6 GO:0045995 regulation of embryonic development 6/580 64/18722 0.0141435065837254 0.0856529285428473 LAMA5/DAG1/NIPBL/CFL1/PHLDA2/CDK1 6 GO:1900076 regulation of cellular response to insulin stimulus 6/580 64/18722 0.0141435065837254 0.0856529285428473 ATP2B1/KANK1/ESRRA/GNAI2/PRKCZ/IGF2 6 GO:0006575 cellular modified amino acid metabolic process 12/580 188/18722 0.0144048941953958 0.0867488244520754 FOLR1/SERINC1/SLC19A1/PCYOX1/POR/PTGES2/GSTO1/CROT/ARL6IP5/TYMS/GPX1/CLIC3 12 GO:0031397 negative regulation of protein ubiquitination 7/580 83/18722 0.0144359560206252 0.0867488244520754 RPS20/UFL1/RPL23/SOX4/HSPA1A/PPIA/CAV1 7 GO:0005996 monosaccharide metabolic process 15/580 257/18722 0.0144601188827399 0.0867488244520754 GAPDH/GAA/SLC2A1/ALDOA/ENO1/LRP5/DDB1/PMAIP1/FUCA1/TPI1/GSTO1/PHLDA2/PGP/HMGB1/IGF2 15 GO:0030307 positive regulation of cell growth 11/580 166/18722 0.0144987678442627 0.0867488244520754 LRP1/EGFR/GOLGA4/MACF1/SLC9A1/EIF4G1/S100A9/RHOA/CDC42/CYBA/RAB11A 11 GO:0043112 receptor metabolic process 11/580 166/18722 0.0144987678442627 0.0867488244520754 LRP1/ITGB1/LRPAP1/RNF43/ZNRF3/ADM/TFRC/CD81/CAV1/MYLIP/LGMN 11 GO:0051236 establishment of RNA localization 11/580 166/18722 0.0144987678442627 0.0867488244520754 ZFP36L1/HNRNPA1/YBX1/PABPN1/NPM1/THOC2/TPR/HNRNPA2B1/HNRNPA3/RAN/SRSF3 11 GO:1902904 negative regulation of supramolecular fiber organization 11/580 166/18722 0.0144987678442627 0.0867488244520754 KANK1/MET/SPTAN1/SPTBN1/TACSTD2/TMSB4X/WASF2/TRIOBP/PFN1/HSPA8/STMN1 11 GO:0016264 gap junction assembly 3/580 17/18722 0.0145482870506598 0.0867488244520754 GJA5/GJA1/CAV1 3 GO:0033151 V(D)J recombination 3/580 17/18722 0.0145482870506598 0.0867488244520754 PRKDC/HMGB1/HMGB2 3 GO:0045198 establishment of epithelial cell apical/basal polarity 3/580 17/18722 0.0145482870506598 0.0867488244520754 FAT1/RHOA/CDC42 3 GO:0046827 positive regulation of protein export from nucleus 3/580 17/18722 0.0145482870506598 0.0867488244520754 TCF7L2/TPR/YWHAE 3 GO:0048532 anatomical structure arrangement 3/580 17/18722 0.0145482870506598 0.0867488244520754 NRP2/HSPA5/TFAP2A 3 GO:0045639 positive regulation of myeloid cell differentiation 8/580 103/18722 0.0146986490535653 0.0872113150616307 JUN/FOS/HSPA1A/ZFP36L1/ATP6AP1/PRKDC/HMGB1/HMGB2 8 GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 5/580 47/18722 0.0147350057887012 0.0872113150616307 ENPEP/ADRB1/ATP6AP2/RHOA/CYBA 5 GO:0010799 regulation of peptidyl-threonine phosphorylation 5/580 47/18722 0.0147350057887012 0.0872113150616307 APP/CALM1/EIF4G1/BMP7/CALM2 5 GO:0042311 vasodilation 5/580 47/18722 0.0147350057887012 0.0872113150616307 EGFR/GJA5/GJA1/ADRB1/GPX1 5 GO:0045646 regulation of erythrocyte differentiation 5/580 47/18722 0.0147350057887012 0.0872113150616307 HSPA1A/ZFP36L1/PRKDC/CDK6/HMGB2 5 GO:0007190 activation of adenylate cyclase activity 4/580 31/18722 0.0147758581527768 0.0872113150616307 LGR5/LGR4/ADRB1/CALM1 4 GO:0030201 heparan sulfate proteoglycan metabolic process 4/580 31/18722 0.0147758581527768 0.0872113150616307 EXTL2/GPC1/B3GAT3/TCF7L2 4 GO:1900027 regulation of ruffle assembly 4/580 31/18722 0.0147758581527768 0.0872113150616307 KANK1/TACSTD2/CAV1/PFN1 4 GO:0043410 positive regulation of MAPK cascade 24/580 480/18722 0.0150517196482828 0.0887269303981791 LRP1/EGFR/GADD45B/APP/IQGAP1/ERP29/TPBG/ATP6AP1/IGF1R/ROCK1/HMGCR/MAGED1/CD81/EMC10/PPIA/MIF/MYDGF/GADD45G/GNAI2/ARL6IP5/PRKCZ/HMGB1/IGF2/CDC42 24 GO:1903532 positive regulation of secretion by cell 16/580 282/18722 0.015075408411536 0.0887540816734862 LRP1/EGFR/KCNN4/WLS/SOX4/MYH10/ISL1/GJA1/ATP6AP1/KIF5B/TCF7L2/SLC6A4/PPIA/FRMD4A/DYNLL1/PHPT1 16 GO:0048645 animal organ formation 6/580 65/18722 0.0151866493195284 0.0892959620545216 LRP2/ISL1/FOLR1/GLI3/CITED2/BMP7 6 GO:0003002 regionalization 18/580 331/18722 0.0154062635712239 0.0904728937749527 LRP2/NRP2/ADGRG1/WLS/ISL1/BPTF/LRP5/PBX1/GLI3/DDIT3/PRKDC/IRX2/TBX3/GPC3/CITED2/ATP6AP2/NR2F2/TRA2B 18 GO:0048661 positive regulation of smooth muscle cell proliferation 8/580 104/18722 0.0155069842140265 0.0908349919136487 JUN/EGFR/ADAMTS1/GJA1/HMGCR/GNAI2/HPGD/CYBA 8 GO:1903076 regulation of protein localization to plasma membrane 8/580 104/18722 0.0155069842140265 0.0908349919136487 LRP1/EGFR/ITGB1/SPTBN1/KIF5B/HECTD1/TMEM59/RAB11A 8 GO:0030041 actin filament polymerization 12/580 190/18722 0.0155423678555805 0.0909277394922075 IQGAP2/KANK1/SPTAN1/SPTBN1/DIAPH1/TMSB4X/WASF2/TRIOBP/MSRB2/PFN1/RASA1/RHOA 12 GO:0042542 response to hydrogen peroxide 10/580 146/18722 0.0156129368833774 0.0912258410107891 JUN/LDHA/RHOB/MET/DUSP1/TXN/GPX1/TXNIP/PCNA/CDK1 10 GO:0030072 peptide hormone secretion 14/580 236/18722 0.0156358997950444 0.091245382618258 LRP1/EGFR/SOX4/ISL1/LRP5/GJA1/DPP4/HMGCR/KIF5B/TCF7L2/HMGN3/DYNLL1/FAM3B/PHPT1 14 GO:0048880 sensory system development 20/580 381/18722 0.0157137218092684 0.0915846116978787 FBN1/FBN2/ATP2B1/TENM3/EFEMP1/NAGLU/SERPINF1/ISL1/LRP5/CRYBG3/FAT1/PBX1/GLI3/SMOC1/CITED2/NIPBL/BMP7/TUG1/TFAP2A/HMGB1 20 GO:2000027 regulation of animal organ morphogenesis 9/580 125/18722 0.0158086080451014 0.0920223229258655 LGR4/ZNRF3/TACSTD2/MAGED1/GPC3/CITED2/BMP7/RHOA/CDC42 9 GO:0032527 protein exit from endoplasmic reticulum 5/580 48/18722 0.0160413320921653 0.0931438646200509 HSP90B1/GCC2/OS9/CD81/HM13 5 GO:0042149 cellular response to glucose starvation 5/580 48/18722 0.0160413320921653 0.0931438646200509 HSPA5/SLC2A1/HNRNPA1/PMAIP1/XBP1 5 GO:0014015 positive regulation of gliogenesis 6/580 66/18722 0.0162819529195616 0.0942966787788854 LRP2/EGFR/SPINT1/DAG1/UFL1/IL6ST 6 GO:0062207 regulation of pattern recognition receptor signaling pathway 8/580 105/18722 0.0163470262173815 0.0942966787788854 LGR4/HSPA1A/RTN4/PUM1/CAV1/NINJ1/HMGB1/CYBA 8 GO:0070372 regulation of ERK1 and ERK2 cascade 17/580 309/18722 0.0164441176916553 0.0942966787788854 LRP1/EGFR/FBLN1/SEMA6A/APP/DUSP1/DUSP6/EIF3A/TPBG/ATP6AP1/DUSP9/HMGCR/MIF/TIMP3/GNAI2/PRKCZ/HMGB1 17 GO:0006026 aminoglycan catabolic process 4/580 32/18722 0.016483164877926 0.0942966787788854 NAGLU/GUSB/GNS/FUCA1 4 GO:0007435 salivary gland morphogenesis 4/580 32/18722 0.016483164877926 0.0942966787788854 LAMA5/DAG1/BMP7/CDC42 4 GO:0021799 cerebral cortex radially oriented cell migration 4/580 32/18722 0.016483164877926 0.0942966787788854 LAMB1/ADGRG1/GLI3/RTN4 4 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 4/580 32/18722 0.016483164877926 0.0942966787788854 TGFBR3/FERMT1/CITED2/CDKN1C 4 GO:0035767 endothelial cell chemotaxis 4/580 32/18722 0.016483164877926 0.0942966787788854 MET/TMSB4X/LGMN/HMGB1 4 GO:0050685 positive regulation of mRNA processing 4/580 32/18722 0.016483164877926 0.0942966787788854 TRA2B/HSPA8/CIRBP/NCL 4 GO:0051642 centrosome localization 4/580 32/18722 0.016483164877926 0.0942966787788854 AKAP9/SYNE2/KIF5B/ASPM 4 GO:0060323 head morphogenesis 4/580 32/18722 0.016483164877926 0.0942966787788854 ANKRD11/ATP6AP2/NIPBL/ARID5B 4 GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 4/580 32/18722 0.016483164877926 0.0942966787788854 TGFBR3/FERMT1/CITED2/CDKN1C 4 GO:2001235 positive regulation of apoptotic signaling pathway 9/580 126/18722 0.0165747445467891 0.0947040993699216 CTSC/DDIT3/PDIA3/PMAIP1/MAGED1/SIAH1/CAV1/TIMP3/S100A9 9 GO:0042391 regulation of membrane potential 22/580 434/18722 0.0168389527318084 0.0960956676756329 JUN/AKAP9/APP/KCNN4/GABRE/DSG2/GJA5/GJA1/ADRB1/SLC9A1/GNAQ/CALM1/SLC25A36/KIF5B/PMAIP1/DSC2/CAV1/DSP/ARL6IP5/PRKCZ/YWHAE/YWHAH 22 GO:0071900 regulation of protein serine/threonine kinase activity 19/580 359/18722 0.016896497987475 0.096305897230081 EGFR/DUSP1/CCNL1/SERTAD1/IQGAP1/ERP29/LRP5/HMGCR/CALM1/MAGED1/NR2F2/BMP7/CAV1/CDKN1C/CCND3/CALM2/RHOA/CKS1B/IGF2 19 GO:0009636 response to toxic substance 15/580 262/18722 0.0169371977932083 0.0964197147322052 FOS/CDH1/MGST3/SOD3/UBA52/SLC6A4/BMP7/GSTO1/TXN/GPX3/S100A9/TYMS/GPX1/DHRS2/CDK1 15 GO:0036499 PERK-mediated unfolded protein response 3/580 18/18722 0.0170633359365163 0.09678240907407 HSPA5/DDIT3/PPP1R15A 3 GO:0061484 hematopoietic stem cell homeostasis 3/580 18/18722 0.0170633359365163 0.09678240907407 ADGRG1/SOX4/FSTL1 3 GO:1902074 response to salt 3/580 18/18722 0.0170633359365163 0.09678240907407 HSPA5/HNRNPA1/HNRNPD 3 GO:0006090 pyruvate metabolic process 8/580 106/18722 0.0172194176923703 0.0971935821446774 GAPDH/LDHA/APP/ALDOA/ENO1/TPI1/PKM/VDAC1 8 GO:0006766 vitamin metabolic process 8/580 106/18722 0.0172194176923703 0.0971935821446774 LRP2/SLC2A1/SLC52A1/FOLR1/SLC52A2/SLC19A1/GSTO1/LGMN 8 GO:0035821 modulation of process of other organism 8/580 106/18722 0.0172194176923703 0.0971935821446774 JUN/DAG1/EIF2AK4/CFL1/STOM/S100A9/HSPA8/SERPINB9 8 GO:2000278 regulation of DNA biosynthetic process 8/580 106/18722 0.0172194176923703 0.0971935821446774 DUSP1/GJA1/HNRNPA1/PTGES3/HNRNPC/HNRNPD/HNRNPA2B1/PCNA 8 GO:0046580 negative regulation of Ras protein signal transduction 5/580 49/18722 0.0174225349176629 0.0978649878044082 ITGB1/KANK1/MET/RASA1/STMN1 5 GO:0060964 regulation of gene silencing by miRNA 5/580 49/18722 0.0174225349176629 0.0978649878044082 NEAT1/EGFR/KCNQ1OT1/PUM1/EIF4G1 5 GO:0070169 positive regulation of biomineral tissue development 5/580 49/18722 0.0174225349176629 0.0978649878044082 FBN2/ATP2B1/BMP7/TFAP2A/ATRAID 5 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 5/580 49/18722 0.0174225349176629 0.0978649878044082 JUN/ADAMTS1/GJA1/GNAI2/HPGD 5 GO:0140014 mitotic nuclear division 16/580 287/18722 0.0175049119648958 0.0982091019888183 DUSP1/HSPA1A/LRP5/ATRX/PHIP/CENPF/NIPBL/BMP7/TPR/RHOA/RAN/IGF2/CDC42/ANAPC11/RANBP1/RAB11A 16 GO:0042110 T cell activation 24/580 487/18722 0.0176112313129392 0.0986865504053981 CTSL/EGR1/RPS6/CD46/SOX4/NCSTN/ZFP36L1/GLI3/DDOST/PRKDC/DPP4/DLG5/TFRC/CD81/EIF2AK4/CAV1/IL6ST/XBP1/CD55/CCND3/PRKCZ/RHOA/HMGB1/IGF2 24 GO:0034599 cellular response to oxidative stress 16/580 288/18722 0.018025041827585 0.100803301746702 JUN/FOS/EGFR/RHOB/P4HB/SOD3/MET/HSPA1A/PPIA/BMP7/TXN/ARL6IP5/GPX1/PCNA/DHRS2/CDK1 16 GO:0008154 actin polymerization or depolymerization 13/580 217/18722 0.0180323257478513 0.100803301746702 IQGAP2/KANK1/SPTAN1/SPTBN1/DIAPH1/CFL1/TMSB4X/WASF2/TRIOBP/MSRB2/PFN1/RASA1/RHOA 13 GO:0010927 cellular component assembly involved in morphogenesis 8/580 107/18722 0.0181247927624294 0.101198572794789 ITGB4/DAG1/KRT19/ITGB1/PLEC/GPC1/ACTG1/KRT8 8 GO:1900182 positive regulation of protein localization to nucleus 7/580 87/18722 0.0183010673627809 0.101617299032227 CDH1/GLI3/TFRC/NPM1/TPR/RAN/CDK1 7 GO:0031116 positive regulation of microtubule polymerization 4/580 33/18722 0.0183090295826718 0.101617299032227 AKAP9/CLIP1/MET/HSPA1A 4 GO:0046685 response to arsenic-containing substance 4/580 33/18722 0.0183090295826718 0.101617299032227 SERPINF1/SLC38A2/HNRNPA1/GSTO1 4 GO:0061842 microtubule organizing center localization 4/580 33/18722 0.0183090295826718 0.101617299032227 AKAP9/SYNE2/KIF5B/ASPM 4 GO:0071353 cellular response to interleukin-4 4/580 33/18722 0.0183090295826718 0.101617299032227 RPLP0/HSPA5/XBP1/TUBA1B 4 GO:1901136 carbohydrate derivative catabolic process 11/580 172/18722 0.0184184269877452 0.102102626841481 CTSL/NAGLU/HEXA/GPC1/GUSB/MANBA/GNS/FUCA1/NEU1/MGAT1/DUT 11 GO:0010812 negative regulation of cell-substrate adhesion 6/580 68/18722 0.0186336321763101 0.102805484284719 LRP1/FBLN1/KANK1/TACSTD2/RASA1/RHOA 6 GO:0042698 ovulation cycle 6/580 68/18722 0.0186336321763101 0.102805484284719 EGFR/HSPA5/EGR1/SERPINF1/ADAMTS1/PCNA 6 GO:0051926 negative regulation of calcium ion transport 6/580 68/18722 0.0186336321763101 0.102805484284719 CALM1/C4orf3/GSTO1/CALM2/VDAC1/YWHAE 6 GO:1902305 regulation of sodium ion transmembrane transport 6/580 68/18722 0.0186336321763101 0.102805484284719 UTRN/SLC9A1/KIF5B/STOM/FXYD3/YWHAH 6 GO:0010498 proteasomal protein catabolic process 24/580 490/18722 0.018808153706544 0.103645406266749 HSP90B1/HSPA5/UFL1/NHLRC3/HSPA1A/TMEM259/DDIT3/DDB1/OS9/PMAIP1/HECTD1/SIAH1/DNAJB14/NEMF/CAV1/PSMD1/CCDC47/HM13/CANX/SIAH2/EIF3H/GPX1/UBXN4/ANAPC11 24 GO:0060688 regulation of morphogenesis of a branching structure 5/580 50/18722 0.0188801991959218 0.103796461536918 LGR4/TACSTD2/RTN4/MAGED1/BMP7 5 GO:0110151 positive regulation of biomineralization 5/580 50/18722 0.0188801991959218 0.103796461536918 FBN2/ATP2B1/BMP7/TFAP2A/ATRAID 5 GO:0002790 peptide secretion 14/580 242/18722 0.0190105106879562 0.104389474863854 LRP1/EGFR/SOX4/ISL1/LRP5/GJA1/DPP4/HMGCR/KIF5B/TCF7L2/HMGN3/DYNLL1/FAM3B/PHPT1 14 GO:0006022 aminoglycan metabolic process 9/580 129/18722 0.0190360793950659 0.104406609984023 ITIH5/CHPF/NAGLU/HEXA/GUSB/CHST12/B3GAT3/GNS/FUCA1 9 GO:0033138 positive regulation of peptidyl-serine phosphorylation 8/580 108/18722 0.0190637763861905 0.10443536392482 AKAP9/EGFR/APP/TFRC/EIF4G1/CAV1/MIF/TXN 8 GO:0051090 regulation of DNA-binding transcription factor activity 22/580 440/18722 0.0193638912857162 0.105832417888991 APP/UFL1/PLPP3/HSPA1A/LRP5/DDIT3/PURA/TFRC/KDM5A/NPM1/TCF7L2/PPIA/EIF2AK4/BMP7/CAV1/TMSB4X/ARID5B/ID1/NFKBIA/S100A9/PRKCZ/ANXA4 22 GO:0043393 regulation of protein binding 12/580 196/18722 0.0193643060897724 0.105832417888991 LRP1/APP/TGFBR3/LRPAP1/PTPRF/ROCK1/TCF7L2/CAV1/ID1/PHLDA2/RAN/CDC42 12 GO:0009896 positive regulation of catabolic process 24/580 492/18722 0.0196409844260213 0.106614920377502 LRP2/LRP1/APP/KCNQ1OT1/UFL1/HSPA1A/ZFP36L1/CTSC/TMEM259/GJA1/TNRC6A/DDB1/ROCK1/GPC3/HECTD1/CD81/PUM1/VGLL4/CAV1/TMEM59/MYLIP/HNRNPD/HMGB1/VDAC1 24 GO:0060485 mesenchyme development 16/580 291/18722 0.0196568258131694 0.106614920377502 LAMA5/NRP2/DAG1/SEMA6A/SEMA6D/TGFBR3/ZFP36L1/ISL1/FOLR1/ROCK1/RTN4/TBX3/DLG5/CITED2/TCF7L2/BMP7 16 GO:0002523 leukocyte migration involved in inflammatory response 3/580 19/18722 0.0198054808011528 0.106614920377502 JAM3/NINJ1/S100A9 3 GO:0007039 protein catabolic process in the vacuole 3/580 19/18722 0.0198054808011528 0.106614920377502 LRP2/LRP1/CD81 3 GO:0007213 G protein-coupled acetylcholine receptor signaling pathway 3/580 19/18722 0.0198054808011528 0.106614920377502 GNAQ/GNAI2/RGS10 3 GO:0030011 maintenance of cell polarity 3/580 19/18722 0.0198054808011528 0.106614920377502 DST/SLC9A1/DLG5 3 GO:0035461 vitamin transmembrane transport 3/580 19/18722 0.0198054808011528 0.106614920377502 LRP2/FOLR1/SLC19A1 3 GO:0036498 IRE1-mediated unfolded protein response 3/580 19/18722 0.0198054808011528 0.106614920377502 HSPA5/UFL1/XBP1 3 GO:0044827 modulation by host of viral genome replication 3/580 19/18722 0.0198054808011528 0.106614920377502 EIF2AK4/STOM/HSPA8 3 GO:0045780 positive regulation of bone resorption 3/580 19/18722 0.0198054808011528 0.106614920377502 EGFR/ATP6AP1/TFRC 3 GO:0045947 negative regulation of translational initiation 3/580 19/18722 0.0198054808011528 0.106614920377502 RPL13A/EIF2AK4/TPR 3 GO:0046794 transport of virus 3/580 19/18722 0.0198054808011528 0.106614920377502 CTSL/CAV1/DYNLT1 3 GO:0070262 peptidyl-serine dephosphorylation 3/580 19/18722 0.0198054808011528 0.106614920377502 DUSP1/PPP1R15A/YWHAE 3 GO:1904377 positive regulation of protein localization to cell periphery 6/580 69/18722 0.0198922146231391 0.106958023366728 LRP1/EGFR/ITGB1/SPTBN1/KIF5B/RAB11A 6 GO:0032414 positive regulation of ion transmembrane transporter activity 8/580 109/18722 0.0200369837103429 0.1076120222134 AKAP9/TCAF1/SLC9A1/CALM1/KIF5B/GSTO1/TMSB4X/CALM2 8 GO:0006898 receptor-mediated endocytosis 14/580 244/18722 0.0202498215753248 0.108161540105712 LRP2/LRP1/CTSL/ITGAV/AAK1/ITGB1/LRPAP1/FOLR1/ADM/TFRC/CD81/CAV1/AP1S1/CANX 14 GO:0001662 behavioral fear response 4/580 34/18722 0.0202555797531875 0.108161540105712 GJA1/DPP4/EIF4G1/VDAC1 4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 4/580 34/18722 0.0202555797531875 0.108161540105712 CTSL/CTSD/CTSV/LGMN 4 GO:0007431 salivary gland development 4/580 34/18722 0.0202555797531875 0.108161540105712 LAMA5/DAG1/BMP7/CDC42 4 GO:0010922 positive regulation of phosphatase activity 4/580 34/18722 0.0202555797531875 0.108161540105712 SLC39A10/PPP1R15A/CALM1/CALM2 4 GO:0051348 negative regulation of transferase activity 15/580 268/18722 0.0203253543448084 0.108409659469844 RPS20/GADD45B/PLEC/RPL23/DUSP1/LRP5/GNAQ/HMGCR/NPM1/NR2F2/PPIA/BMP7/CAV1/CDKN1C/PHPT1 15 GO:0051293 establishment of spindle localization 5/580 51/18722 0.0204158251065887 0.108643023536321 DYNC1H1/ITGB1/GJA1/CFL1/DYNLT1 5 GO:0060043 regulation of cardiac muscle cell proliferation 5/580 51/18722 0.0204158251065887 0.108643023536321 TGFBR3/GJA1/CITED2/VGLL4/CDK1 5 GO:0009101 glycoprotein biosynthetic process 17/580 317/18722 0.0205386988005702 0.109171986424517 CHPF/RPN2/NCSTN/EXTL2/CHST12/B3GAT3/DDOST/TRIP11/C1GALT1/GALNT11/MAN1A2/TCF7L2/MGAT1/MPDU1/ITM2B/TMEM59/TUSC3 17 GO:1903706 regulation of hemopoiesis 19/580 367/18722 0.0207319356041019 0.110073324765614 FBN1/JUN/FOS/CSF3R/CD46/SOX4/HSPA1A/ZFP36L1/ESRRA/ATP6AP1/GLI3/PRKDC/CDK6/XBP1/NFKBIA/PRKCZ/RHOA/HMGB1/HMGB2 19 GO:0000723 telomere maintenance 9/580 131/18722 0.0208176698100684 0.11015128815316 PPP1R10/HNRNPA1/PRKDC/ATRX/PTGES3/HNRNPC/HNRNPD/HNRNPA2B1/PCNA 9 GO:0019079 viral genome replication 9/580 131/18722 0.0208176698100684 0.11015128815316 DDB1/HACD3/PKN2/PPIA/EIF2AK4/STOM/MPHOSPH8/HSPA8/CDC42 9 GO:0019827 stem cell population maintenance 9/580 131/18722 0.0208176698100684 0.11015128815316 TPT1/ZC3H13/SOX4/LRP5/TBX3/NIPBL/BMP7/ASPM/NCOA3 9 GO:0006814 sodium ion transport 14/580 245/18722 0.0208918739282563 0.110418301864 UTRN/SLC3A2/SLC38A2/SLC38A10/MAGED2/SLC38A1/SLC9A1/KIF5B/SLC13A4/SLC6A4/STOM/PRSS8/FXYD3/YWHAH 14 GO:0007409 axonogenesis 21/580 418/18722 0.0209831614107751 0.110774896392185 LAMA5/LRP1/NRP2/DAG1/GOLGA4/MACF1/SEMA6A/APP/SEMA6D/ITGB1/MYCBP2/BSG/ISL1/EPHB4/GLI3/RTN4/KIF5B/SIAH1/BMP7/STMN1/RAB11A 21 GO:0002028 regulation of sodium ion transport 7/580 90/18722 0.0216397556651434 0.113780210799862 UTRN/SLC9A1/KIF5B/STOM/PRSS8/FXYD3/YWHAH 7 GO:0042475 odontogenesis of dentin-containing tooth 7/580 90/18722 0.0216397556651434 0.113780210799862 LAMA5/CSF3R/ANKRD11/BSG/GLI3/ADM/BMP7 7 GO:0046031 ADP metabolic process 7/580 90/18722 0.0216397556651434 0.113780210799862 GAPDH/LDHA/APP/ALDOA/ENO1/TPI1/PKM 7 GO:0008202 steroid metabolic process 17/580 319/18722 0.0216747509715498 0.113780210799862 LRP2/EGR1/APP/DHCR24/SF1/LRP5/PBX1/ADM/HMGCR/SLC27A2/POR/PRLR/HSD17B1/LGMN/ACADVL/YWHAH/DHRS2 17 GO:1901214 regulation of neuron death 17/580 319/18722 0.0216747509715498 0.113780210799862 JUN/LRP1/FOS/GRN/EGR1/SERPINF1/ISL1/TMEM259/DHCR24/ERBB3/DDIT3/EIF4G1/LGMN/TFAP2A/RASA1/RHOA/CDC42 17 GO:0007569 cell aging 9/580 132/18722 0.0217521229697836 0.114057636902439 YBX1/PRKDC/TBX3/YPEL3/NPM1/CITED2/CDK6/MIF/CDK1 9 GO:0008360 regulation of cell shape 10/580 154/18722 0.021809907041648 0.114231844201244 DAG1/RHOB/ALDOA/MYH10/DIAPH1/PHIP/MYL12B/RASA1/RHOA/MYL12A 10 GO:0046879 hormone secretion 16/580 295/18722 0.0220051896516441 0.114871492796726 LRP1/EGFR/SOX4/ISL1/LRP5/GJA1/ADM/DPP4/HMGCR/TBX3/KIF5B/TCF7L2/HMGN3/DYNLL1/FAM3B/PHPT1 16 GO:0032206 positive regulation of telomere maintenance 5/580 52/18722 0.022030825967465 0.114871492796726 PPP1R10/HNRNPA1/ATRX/HNRNPD/HNRNPA2B1 5 GO:0043090 amino acid import 5/580 52/18722 0.022030825967465 0.114871492796726 ITGB1/SLC3A2/SLC1A5/SLC43A2/ARL6IP5 5 GO:0060147 regulation of posttranscriptional gene silencing 5/580 52/18722 0.022030825967465 0.114871492796726 NEAT1/EGFR/KCNQ1OT1/PUM1/EIF4G1 5 GO:0030324 lung development 11/580 177/18722 0.0222450130078866 0.115241059641978 LAMA5/EGFR/DAG1/GLI3/DLG5/GPC3/MAN1A2/SRSF6/PTGES3/HMGB1/CDC42 11 GO:0051302 regulation of cell division 11/580 177/18722 0.0222450130078866 0.115241059641978 YBX1/CALM1/PKN2/ASPM/NCOA3/CALM2/RHOA/IGF2/TXNIP/CDC42/RAB11A 11 GO:0071453 cellular response to oxygen levels 11/580 177/18722 0.0222450130078866 0.115241059641978 MALAT1/EGR1/P4HB/ENO1/ZFP36L1/ATP6AP1/SLC9A1/PMAIP1/CITED2/BMP7/CAV1 11 GO:0009416 response to light stimulus 17/580 320/18722 0.0222604347481178 0.115241059641978 FOS/EGFR/JUND/APP/ITGB1/DUSP1/TP53I13/DDB1/GNAQ/HMGCR/NPM1/EIF2AK4/NR2F6/GPX1/CIRBP/DYNLRB1/PCNA 17 GO:0002209 behavioral defense response 4/580 35/18722 0.0223247032331589 0.115241059641978 GJA1/DPP4/EIF4G1/VDAC1 4 GO:0032350 regulation of hormone metabolic process 4/580 35/18722 0.0223247032331589 0.115241059641978 EGR1/ADM/POR/TCF7L2 4 GO:0034405 response to fluid shear stress 4/580 35/18722 0.0223247032331589 0.115241059641978 PLEC/GJA1/CITED2/TFPI2 4 GO:0086005 ventricular cardiac muscle cell action potential 4/580 35/18722 0.0223247032331589 0.115241059641978 DSG2/DSC2/CAV1/DSP 4 GO:0098801 regulation of renal system process 4/580 35/18722 0.0223247032331589 0.115241059641978 GJA5/GJA1/GNAI2/CYBA 4 GO:0033555 multicellular organismal response to stress 6/580 71/18722 0.0225801015674461 0.115517659775912 VWA1/GJA1/ADRB1/DPP4/EIF4G1/VDAC1 6 GO:0061515 myeloid cell development 6/580 71/18722 0.0225801015674461 0.115517659775912 FBN1/APP/RPS6/ATP6AP1/CITED2/WASF2 6 GO:0048193 Golgi vesicle transport 16/580 296/18722 0.0226241888242482 0.115517659775912 GOLGA4/MACF1/LMAN1/PLPP3/SPTBN1/TRIP11/GCC2/TMED9/TMED1/COPA/CUX1/VAMP2/SCAMP2/TMED4/LMAN2/ARF5 16 GO:0006606 protein import into nucleus 10/580 155/18722 0.0226943405600768 0.115517659775912 CDH1/RPL23/PPP1R10/GLI3/FERMT1/TPR/NFKBIA/RAN/TXNIP/CDK1 10 GO:0010970 transport along microtubule 10/580 155/18722 0.0226943405600768 0.115517659775912 ARMCX3/DYNC1H1/APP/DST/PURA/KIF5B/ARHGAP21/HSPA8/PRKCZ/CDC42 10 GO:0034614 cellular response to reactive oxygen species 10/580 155/18722 0.0226943405600768 0.115517659775912 JUN/FOS/EGFR/RHOB/SOD3/MET/BMP7/TXN/PCNA/CDK1 10 GO:0010595 positive regulation of endothelial cell migration 9/580 133/18722 0.0227163095407842 0.115517659775912 NRP2/GRN/RHOB/MET/PLPP3/EMC10/TMSB4X/LGMN/HMGB1 9 GO:0046887 positive regulation of hormone secretion 9/580 133/18722 0.0227163095407842 0.115517659775912 LRP1/EGFR/SOX4/ISL1/GJA1/KIF5B/TCF7L2/DYNLL1/PHPT1 9 GO:0003159 morphogenesis of an endothelium 3/580 20/18722 0.0227756813619676 0.115517659775912 RHOB/RHOA/CSNK2B 3 GO:0007097 nuclear migration 3/580 20/18722 0.0227756813619676 0.115517659775912 DYNC1H1/SYNE2/CDC42 3 GO:0010523 negative regulation of calcium ion transport into cytosol 3/580 20/18722 0.0227756813619676 0.115517659775912 CALM1/GSTO1/CALM2 3 GO:0010801 negative regulation of peptidyl-threonine phosphorylation 3/580 20/18722 0.0227756813619676 0.115517659775912 CALM1/EIF4G1/CALM2 3 GO:0032930 positive regulation of superoxide anion generation 3/580 20/18722 0.0227756813619676 0.115517659775912 EGFR/GNAI2/CYBA 3 GO:0060044 negative regulation of cardiac muscle cell proliferation 3/580 20/18722 0.0227756813619676 0.115517659775912 GJA1/CITED2/VGLL4 3 GO:0061154 endothelial tube morphogenesis 3/580 20/18722 0.0227756813619676 0.115517659775912 RHOB/RHOA/CSNK2B 3 GO:0071243 cellular response to arsenic-containing substance 3/580 20/18722 0.0227756813619676 0.115517659775912 SLC38A2/HNRNPA1/GSTO1 3 GO:0001654 eye development 19/580 371/18722 0.0228851933065512 0.115946660205631 FBN1/FBN2/ATP2B1/TENM3/EFEMP1/NAGLU/SERPINF1/LRP5/CRYBG3/FAT1/PBX1/GLI3/SMOC1/CITED2/NIPBL/BMP7/TUG1/TFAP2A/HMGB1 19 GO:0072594 establishment of protein localization to organelle 21/580 422/18722 0.0230064941834351 0.116403056493544 HSPA5/CDH1/LMAN1/RPL23/PPP1R10/GLI3/DDIT3/FERMT1/GCC2/CALM1/SEC62/NIPBL/TPR/LEPROT/NFKBIA/HSPA8/RAN/TXNIP/CDK1/UBE2L3/RAB11A 21 GO:0006403 RNA localization 12/580 201/18722 0.0230520269775912 0.116403056493544 ZFP36L1/HNRNPA1/YBX1/PABPN1/NPM1/THOC2/TPR/HNRNPA2B1/HNRNPA3/RAN/SRSF3/FBL 12 GO:0051054 positive regulation of DNA metabolic process 12/580 201/18722 0.0230520269775912 0.116403056493544 EGFR/PPP1R10/HNRNPA1/PRKDC/ATRX/TFRC/FUS/PTGES3/HNRNPD/HNRNPA2B1/HMGB1/PCNA 12 GO:0035265 organ growth 11/580 178/18722 0.0230753855272086 0.116403056493544 TGFBR3/PSAP/DUSP6/GJA1/DUSP9/POR/CITED2/VGLL4/SLC6A4/IGF2/CDK1 11 GO:1901222 regulation of NIK/NF-kappaB signaling 8/580 112/18722 0.02316793895905 0.116673882737407 EGFR/APP/NFAT5/BMP7/TMSB4X/NFKBIA/RHOA/HMGB1 8 GO:0022407 regulation of cell-cell adhesion 22/580 448/18722 0.0231792448181818 0.116673882737407 TENM3/CDH1/CD46/SPINT2/SOX4/PLPP3/NFAT5/GLI3/DPP4/DLG5/TFRC/CITED2/CD81/BMP7/CAV1/IL6ST/XBP1/CD55/PRKCZ/RHOA/HMGB1/IGF2 22 GO:0045862 positive regulation of proteolysis 19/580 372/18722 0.0234493228581613 0.117905730392766 GRN/FBLN1/CLDN4/CTSD/APP/NCSTN/HSPA1A/ENO1/CTSC/TMEM259/PMAIP1/HECTD1/CAV1/ASPH/LGMN/S100A9/ARL6IP5/RHOA/HMGB1 19 GO:0046942 carboxylic acid transport 15/580 273/18722 0.0235221054205057 0.118143965778371 LRP2/SLC26A2/ITGB1/SLC3A2/PSAP/SLC38A2/SLC1A5/GJA1/SLC43A2/FOLR1/SLC38A1/SLC19A1/SLC16A12/SLC38A9/ARL6IP5 15 GO:0045926 negative regulation of growth 14/580 249/18722 0.0236142084039996 0.118478622747575 SEMA6A/SEMA6D/HSPA1A/ENO1/GJA1/ADRB1/BTG1/RTN4/GPC3/CITED2/VGLL4/SLC6A4/LGMN/PLAC8 14 GO:0098727 maintenance of cell number 9/580 134/18722 0.0237106915575153 0.118530692094994 TPT1/ZC3H13/SOX4/LRP5/TBX3/NIPBL/BMP7/ASPM/NCOA3 9 GO:0007566 embryo implantation 5/580 53/18722 0.0237265264116189 0.118530692094994 ITGB4/FBLN1/BSG/GJA1/PRLR 5 GO:0008347 glial cell migration 5/580 53/18722 0.0237265264116189 0.118530692094994 LRP1/LAMB1/ADGRG1/GLI3/RTN4 5 GO:0060966 regulation of gene silencing by RNA 5/580 53/18722 0.0237265264116189 0.118530692094994 NEAT1/EGFR/KCNQ1OT1/PUM1/EIF4G1 5 GO:0042273 ribosomal large subunit biogenesis 6/580 72/18722 0.0240113822489372 0.119825041673613 RPLP0/RPL23A/RPL6/RPL7/RPL14/NPM1 6 GO:1903312 negative regulation of mRNA metabolic process 7/580 92/18722 0.0240867360715282 0.120072250234381 YBX1/NPM1/FUS/SRSF6/HNRNPC/HNRNPD/CIRBP 7 GO:1901342 regulation of vasculature development 18/580 348/18722 0.0241211485583951 0.120115055615734 COL4A2/GRN/RHOB/SEMA6A/ITGB1/SERPINF1/ISL1/ADAMTS1/BTG1/ADM/ROCK1/EMC10/PKM/XBP1/MYDGF/NINJ1/ID1/HMGB1 18 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 4/580 36/18722 0.0245180501071583 0.121312181966376 CTSL/CTSD/CTSV/LGMN 4 GO:0010923 negative regulation of phosphatase activity 4/580 36/18722 0.0245180501071583 0.121312181966376 BOD1L1/PPP1R15A/ROCK1/GNAI2 4 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 4/580 36/18722 0.0245180501071583 0.121312181966376 LRP1/KIF5B/DYNLL1/PHPT1 4 GO:0070670 response to interleukin-4 4/580 36/18722 0.0245180501071583 0.121312181966376 RPLP0/HSPA5/XBP1/TUBA1B 4 GO:0090322 regulation of superoxide metabolic process 4/580 36/18722 0.0245180501071583 0.121312181966376 EGFR/BMP7/GNAI2/CYBA 4 GO:1903539 protein localization to postsynaptic membrane 4/580 36/18722 0.0245180501071583 0.121312181966376 DAG1/VAMP2/PRKCZ/RAB11A 4 GO:0001101 response to acid chemical 9/580 135/18722 0.0247357233353944 0.122259138398426 UFL1/PLEC/SLC38A9/KRT8/XBP1/HNRNPD/RHOA/PCNA/CYBA 9 GO:0010721 negative regulation of cell development 11/580 180/18722 0.0248037379627318 0.122465164824486 FBN1/FBLN1/SEMA6A/SEMA6D/KANK1/TACSTD2/RTN4/BMP7/ID1/YWHAH/DYNLT1 11 GO:0150063 visual system development 19/580 375/18722 0.0252055442803313 0.124317058799386 FBN1/FBN2/ATP2B1/TENM3/EFEMP1/NAGLU/SERPINF1/LRP5/CRYBG3/FAT1/PBX1/GLI3/SMOC1/CITED2/NIPBL/BMP7/TUG1/TFAP2A/HMGB1 19 GO:0007589 body fluid secretion 7/580 93/18722 0.0253787773697067 0.124906554017467 EGFR/KCNN4/PRLR/COPA/CAV1/XBP1/CYBA 7 GO:1901019 regulation of calcium ion transmembrane transporter activity 7/580 93/18722 0.0253787773697067 0.124906554017467 AHNAK/SLC9A1/CALM1/C4orf3/GSTO1/CALM2/YWHAE 7 GO:0002244 hematopoietic progenitor cell differentiation 8/580 114/18722 0.0254371404622901 0.124929398405609 UFL1/PRRC2C/SOX4/RBM47/N4BP2L2/PRKDC/CITED2/JAM3 8 GO:0007041 lysosomal transport 8/580 114/18722 0.0254371404622901 0.124929398405609 LRP1/GRN/RHOB/PSAP/HSPA1A/GCC2/HOOK2/HSPA8 8 GO:0071383 cellular response to steroid hormone stimulus 12/580 204/18722 0.0254994590297934 0.124994575430613 ATP2B1/EGFR/SERPINF1/UFL1/ZFP36L1/ISL1/ESRRA/BMP7/PTGES3/RHOA/YWHAH/UBE2L3 12 GO:2000179 positive regulation of neural precursor cell proliferation 5/580 54/18722 0.0255041608436147 0.124994575430613 LRP2/ADGRG1/GLI3/ASPM/GNAI2 5 GO:0030323 respiratory tube development 11/580 181/18722 0.0257023408625708 0.12557740946042 LAMA5/EGFR/DAG1/GLI3/DLG5/GPC3/MAN1A2/SRSF6/PTGES3/HMGB1/CDC42 11 GO:0032103 positive regulation of response to external stimulus 21/580 427/18722 0.0257430533078306 0.12557740946042 NEAT1/LRP1/EGFR/GRN/APP/MET/CADM1/CTSC/TPBG/PRKDC/CD81/PUM1/IL6ST/TMSB4X/LGMN/NINJ1/NFKBIA/S100A9/HMGB1/HMGB2/CYBA 21 GO:0002689 negative regulation of leukocyte chemotaxis 3/580 21/18722 0.025974084691663 0.12557740946042 DUSP1/DPP4/MIF 3 GO:0008090 retrograde axonal transport 3/580 21/18722 0.025974084691663 0.12557740946042 DYNC1H1/DST/KIF5B 3 GO:0044766 multi-organism transport 3/580 21/18722 0.025974084691663 0.12557740946042 CTSL/CAV1/DYNLT1 3 GO:0045655 regulation of monocyte differentiation 3/580 21/18722 0.025974084691663 0.12557740946042 JUN/ZFP36L1/CDK6 3 GO:0046823 negative regulation of nucleocytoplasmic transport 3/580 21/18722 0.025974084691663 0.12557740946042 FERMT1/TPR/TXN 3 GO:0046885 regulation of hormone biosynthetic process 3/580 21/18722 0.025974084691663 0.12557740946042 EGR1/ADM/POR 3 GO:0060445 branching involved in salivary gland morphogenesis 3/580 21/18722 0.025974084691663 0.12557740946042 LAMA5/DAG1/BMP7 3 GO:0072111 cell proliferation involved in kidney development 3/580 21/18722 0.025974084691663 0.12557740946042 EGR1/GPC3/BMP7 3 GO:0090189 regulation of branching involved in ureteric bud morphogenesis 3/580 21/18722 0.025974084691663 0.12557740946042 LGR4/TACSTD2/MAGED1 3 GO:1902579 multi-organism localization 3/580 21/18722 0.025974084691663 0.12557740946042 CTSL/CAV1/DYNLT1 3 GO:2000178 negative regulation of neural precursor cell proliferation 3/580 21/18722 0.025974084691663 0.12557740946042 SPINT1/SPINT2/SLC6A4 3 GO:1903169 regulation of calcium ion transmembrane transport 10/580 159/18722 0.0264927409342075 0.127951960628244 AHNAK/SLC9A1/DIAPH1/CALM1/C4orf3/GSTO1/CALM2/VDAC1/YWHAE/CYBA 10 GO:0045444 fat cell differentiation 13/580 229/18722 0.0266219732798108 0.128338588126072 ZFP36L1/LRP5/ADRB1/DDIT3/TCF7L2/ARL4A/NIPBL/BMP7/ARID5B/XBP1/ADIRF/GPX1/PLAC8 13 GO:0046916 cellular transition metal ion homeostasis 8/580 115/18722 0.0266279805507761 0.128338588126072 SLC39A10/APP/FTH1/ATP6AP1/TFRC/SLC40A1/SLC39A7/S100A9 8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 7/580 94/18722 0.0267174429431771 0.128546911901726 EGFR/CCNL1/SERTAD1/NR2F2/CDKN1C/CCND3/CKS1B 7 GO:0001990 regulation of systemic arterial blood pressure by hormone 4/580 37/18722 0.0268370353594015 0.128546911901726 ENPEP/ATP6AP2/RHOA/CYBA 4 GO:0031112 positive regulation of microtubule polymerization or depolymerization 4/580 37/18722 0.0268370353594015 0.128546911901726 AKAP9/CLIP1/MET/HSPA1A 4 GO:0045616 regulation of keratinocyte differentiation 4/580 37/18722 0.0268370353594015 0.128546911901726 ZFP36L1/ROCK1/NCOA3/SRSF6 4 GO:0060306 regulation of membrane repolarization 4/580 37/18722 0.0268370353594015 0.128546911901726 AKAP9/GJA5/CAV1/YWHAE 4 GO:0062237 protein localization to postsynapse 4/580 37/18722 0.0268370353594015 0.128546911901726 DAG1/VAMP2/PRKCZ/RAB11A 4 GO:0050671 positive regulation of lymphocyte proliferation 9/580 137/18722 0.0268795124978049 0.128617914225608 SLC39A10/CD46/TFRC/CD81/IL6ST/MIF/CD55/HMGB1/IGF2 9 GO:0030968 endoplasmic reticulum unfolded protein response 6/580 74/18722 0.0270532466853427 0.129050923419004 HSPA5/UFL1/DDIT3/PPP1R15A/OS9/XBP1 6 GO:0048332 mesoderm morphogenesis 6/580 74/18722 0.0270532466853427 0.129050923419004 ITGB4/ITGB1/WLS/GJA1/TBX3/BMP7 6 GO:0120192 tight junction assembly 6/580 74/18722 0.0270532466853427 0.129050923419004 CLDN4/GJA1/LSR/ROCK1/MARVELD3/ACTG1 6 GO:0031113 regulation of microtubule polymerization 5/580 55/18722 0.0273648721656818 0.130137035217368 AKAP9/CLIP1/MET/HSPA1A/STMN1 5 GO:0038066 p38MAPK cascade 5/580 55/18722 0.0273648721656818 0.130137035217368 GADD45B/DUSP1/ZFP36L1/EMC10/GADD45G 5 GO:0043331 response to dsRNA 5/580 55/18722 0.0273648721656818 0.130137035217368 SLC3A2/PMAIP1/NPM1/CAV1/NFKBIA 5 GO:1902105 regulation of leukocyte differentiation 15/580 279/18722 0.0278398573111177 0.132207162987444 FBN1/JUN/FOS/CD46/SOX4/ZFP36L1/ESRRA/ATP6AP1/GLI3/PRKDC/CDK6/XBP1/PRKCZ/RHOA/HMGB1 15 GO:1990748 cellular detoxification 8/580 116/18722 0.0278570242373028 0.132207162987444 MGST3/SOD3/BMP7/GSTO1/TXN/GPX3/S100A9/GPX1 8 GO:0032946 positive regulation of mononuclear cell proliferation 9/580 138/18722 0.0279991364312243 0.132746160592889 SLC39A10/CD46/TFRC/CD81/IL6ST/MIF/CD55/HMGB1/IGF2 9 GO:0030516 regulation of axon extension 7/580 95/18722 0.0281033960607509 0.132969374444102 LRP1/GOLGA4/MACF1/SEMA6A/SEMA6D/RTN4/RAB11A 7 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 7/580 95/18722 0.0281033960607509 0.132969374444102 RPS20/UFL1/RPL23/SOX4/HSPA1A/PPIA/CAV1 7 GO:0045732 positive regulation of protein catabolic process 13/580 231/18722 0.0283040122307748 0.133782480574526 LRP2/LRP1/HSPA1A/CTSC/TMEM259/GJA1/DDB1/GPC3/HECTD1/CD81/VGLL4/CAV1/MYLIP 13 GO:2001257 regulation of cation channel activity 11/580 184/18722 0.0285395137503445 0.134758658327769 AHNAK/APP/ITGB1/CALM1/KIF5B/VAMP2/GSTO1/CAV1/STOM/TMSB4X/CALM2 11 GO:0034121 regulation of toll-like receptor signaling pathway 6/580 75/18722 0.0286655522414318 0.13507951719848 LGR4/RTN4/CAV1/NINJ1/HMGB1/CYBA 6 GO:0043627 response to estrogen 6/580 75/18722 0.0286655522414318 0.13507951719848 LDHA/KRT19/GLI3/CITED2/CAV1/SERPINB9 6 GO:0090596 sensory organ morphogenesis 14/580 256/18722 0.0290028243497531 0.135789297704473 FBN1/FBN2/TENM3/EFEMP1/NAGLU/LRP5/FAT1/GLI3/CITED2/NIPBL/BMP7/TUG1/TRIOBP/TFAP2A 14 GO:0051783 regulation of nuclear division 9/580 139/18722 0.029151142481073 0.135789297704473 DUSP1/LRP5/PHIP/CENPF/BMP7/TPR/IGF2/CDC42/ANAPC11 9 GO:0006402 mRNA catabolic process 13/580 232/18722 0.0291735619594224 0.135789297704473 HSPA1A/ZFP36L1/TNRC6A/YBX1/ROCK1/NPM1/PUM1/FUS/HNRNPC/HNRNPD/CIRBP/CARHSP1/SERBP1 13 GO:0010594 regulation of endothelial cell migration 13/580 232/18722 0.0291735619594224 0.135789297704473 NRP2/GRN/RHOB/SERPINF1/MET/PLPP3/NR2F2/EMC10/TMSB4X/LGMN/RHOA/HMGB1/CSNK2B 13 GO:0002478 antigen processing and presentation of exogenous peptide antigen 4/580 38/18722 0.0292828422279437 0.135789297704473 CTSL/CTSD/CTSV/LGMN 4 GO:0032941 secretion by tissue 4/580 38/18722 0.0292828422279437 0.135789297704473 EGFR/KCNN4/COPA/CYBA 4 GO:0035136 forelimb morphogenesis 4/580 38/18722 0.0292828422279437 0.135789297704473 ATRX/TBX3/NIPBL/TFAP2A 4 GO:2000279 negative regulation of DNA biosynthetic process 4/580 38/18722 0.0292828422279437 0.135789297704473 DUSP1/GJA1/HNRNPA1/HNRNPC 4 GO:0010332 response to gamma radiation 5/580 56/18722 0.029309710764295 0.135789297704473 HSPA5/EGR1/PRKDC/GPX1/CYBA 5 GO:0022029 telencephalon cell migration 5/580 56/18722 0.029309710764295 0.135789297704473 LAMB1/ADGRG1/GLI3/RTN4/RHOA 5 GO:0030166 proteoglycan biosynthetic process 5/580 56/18722 0.029309710764295 0.135789297704473 CHPF/EXTL2/CHST12/B3GAT3/TCF7L2 5 GO:0048255 mRNA stabilization 5/580 56/18722 0.029309710764295 0.135789297704473 YBX1/FUS/HNRNPC/HNRNPD/CIRBP 5 GO:0051058 negative regulation of small GTPase mediated signal transduction 5/580 56/18722 0.029309710764295 0.135789297704473 ITGB1/KANK1/MET/RASA1/STMN1 5 GO:1904645 response to amyloid-beta 5/580 56/18722 0.029309710764295 0.135789297704473 LRP1/APP/GJA1/IGF1R/LGMN 5 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 3/580 22/18722 0.0294000909026886 0.135789297704473 CALM1/GSTO1/CALM2 3 GO:0035089 establishment of apical/basal cell polarity 3/580 22/18722 0.0294000909026886 0.135789297704473 FAT1/RHOA/CDC42 3 GO:0045048 protein insertion into ER membrane 3/580 22/18722 0.0294000909026886 0.135789297704473 EMC1/EMC10/CCDC47 3 GO:0046628 positive regulation of insulin receptor signaling pathway 3/580 22/18722 0.0294000909026886 0.135789297704473 GNAI2/PRKCZ/IGF2 3 GO:0060343 trabecula formation 3/580 22/18722 0.0294000909026886 0.135789297704473 FBN2/TGFBR3/ADAMTS1 3 GO:2000773 negative regulation of cellular senescence 3/580 22/18722 0.0294000909026886 0.135789297704473 YBX1/PRKDC/CDK6 3 GO:0009914 hormone transport 16/580 306/18722 0.0295598770661598 0.136391853407449 LRP1/EGFR/SOX4/ISL1/LRP5/GJA1/ADM/DPP4/HMGCR/TBX3/KIF5B/TCF7L2/HMGN3/DYNLL1/FAM3B/PHPT1 16 GO:0034250 positive regulation of cellular amide metabolic process 10/580 162/18722 0.0296254303237547 0.136558846814453 SOX4/PRKDC/PPP1R15A/NPM1/EIF4G1/EIF2AK4/PKM/HNRNPD/RHOA/CIRBP 10 GO:1902905 positive regulation of supramolecular fiber organization 12/580 209/18722 0.0299927775795495 0.138115255962856 AKAP9/IQGAP2/APP/CLIP1/MET/HSPA1A/WASF2/ID1/PFN1/GPX1/RHOA/CDC42 12 GO:0008217 regulation of blood pressure 11/580 186/18722 0.0305517299395684 0.140411162004874 ATP2B1/ENPEP/GJA5/LRP5/GJA1/ADRB1/ADM/ATP6AP2/NR2F2/RHOA/CYBA 11 GO:0031345 negative regulation of cell projection organization 11/580 186/18722 0.0305517299395684 0.140411162004874 LRP1/SEMA6A/SEMA6D/KANK1/TACSTD2/RTN4/THOC2/MYLIP/ID1/RHOA/YWHAH 11 GO:0010976 positive regulation of neuron projection development 10/580 163/18722 0.0307256036526111 0.141070861390221 LRP1/GRN/TENM3/HSPA5/ITGA6/SERPINF1/IQGAP1/BMP7/S100A9/DYNLT1 10 GO:0031396 regulation of protein ubiquitination 12/580 210/18722 0.0309558733632822 0.14175859011128 RPS20/HSPA5/UFL1/RPL23/SOX4/MYCBP2/HSPA1A/NPM1/PPIA/CAV1/SIAH2/UBE2L3 12 GO:0048588 developmental cell growth 13/580 234/18722 0.0309708078394404 0.14175859011128 LRP1/NRP2/GOLGA4/MACF1/SEMA6A/APP/SEMA6D/ITGB1/IQGAP1/RTN4/EIF2AK4/PRKCZ/RAB11A 13 GO:0060560 developmental growth involved in morphogenesis 13/580 234/18722 0.0309708078394404 0.14175859011128 LRP1/NRP2/GOLGA4/MACF1/SEMA6A/APP/SEMA6D/ITGB1/IQGAP1/RTN4/EIF2AK4/PRKCZ/RAB11A 13 GO:0070167 regulation of biomineral tissue development 7/580 97/18722 0.0310196952515186 0.14175859011128 FBN2/ATP2B1/ROCK1/NOTUM/BMP7/TFAP2A/ATRAID 7 GO:0044262 cellular carbohydrate metabolic process 15/580 283/18722 0.0310277885902566 0.14175859011128 GAA/GUSB/DDB1/ISYNA1/PMAIP1/TPI1/IL6ST/AGL/PHLDA2/PTGES3/PGP/HMGB1/IGF2/PYGL/UGP2 15 GO:0042692 muscle cell differentiation 19/580 384/18722 0.0310757636283689 0.141838446158531 KRT19/ITGB1/PLEC/ISL1/SLC9A1/YBX1/ADM/TBX3/CD81/PLD3/ACTG1/KRT8/XBP1/NINJ1/GPX1/IGF2/CDK1/CACYBP/MORF4L2 19 GO:0007389 pattern specification process 21/580 436/18722 0.0312863805582284 0.142483515697931 LRP2/NRP2/ADGRG1/WLS/ISL1/BPTF/LRP5/FOLR1/PBX1/GLI3/DDIT3/PRKDC/IRX2/TBX3/GALNT11/GPC3/CITED2/ATP6AP2/NR2F2/BMP7/TRA2B 21 GO:0006611 protein export from nucleus 5/580 57/18722 0.0313396337473626 0.142483515697931 TCF7L2/TPR/TXN/RAN/YWHAE 5 GO:0050891 multicellular organismal water homeostasis 5/580 57/18722 0.0313396337473626 0.142483515697931 CLDN4/PLEC/MET/LSR/STMN1 5 GO:0097120 receptor localization to synapse 5/580 57/18722 0.0313396337473626 0.142483515697931 DAG1/KIF5B/VAMP2/PRKCZ/RAB11A 5 GO:0033044 regulation of chromosome organization 11/580 187/18722 0.0315949337115003 0.143503942082215 DUSP1/PPP1R10/HNRNPA1/ATRX/CENPF/TPR/MPHOSPH8/HNRNPC/HNRNPD/HNRNPA2B1/ANAPC11 11 GO:0030282 bone mineralization 8/580 119/18722 0.0317784525789754 0.144180686188904 FBN2/ATP2B1/LGR4/GPC3/NOTUM/BMP7/TFAP2A/ATRAID 8 GO:0046621 negative regulation of organ growth 4/580 39/18722 0.0318564261797916 0.144180686188904 GJA1/CITED2/VGLL4/SLC6A4 4 GO:1901021 positive regulation of calcium ion transmembrane transporter activity 4/580 39/18722 0.0318564261797916 0.144180686188904 SLC9A1/CALM1/GSTO1/CALM2 4 GO:0045930 negative regulation of mitotic cell cycle 13/580 235/18722 0.0318989305715722 0.144180686188904 EGFR/DUSP1/SOX4/ZFP36L1/PPP1R10/BTG1/PRKDC/CENPF/BMP7/TPR/CTDSPL/CDKN1C/CDK1 13 GO:2000116 regulation of cysteine-type endopeptidase activity 13/580 235/18722 0.0318989305715722 0.144180686188904 CTSD/DHCR24/POR/PMAIP1/ASPH/LGMN/SIAH2/S100A9/ARL6IP5/GPX1/RHOA/SERPINB9/HMGB1 13 GO:0045860 positive regulation of protein kinase activity 19/580 386/18722 0.0325086325439415 0.146701387025216 EGFR/DAG1/EGR1/IQGAP1/ERP29/ERBB3/CALM1/MAGED1/NPM1/PPIA/PRLR/TXN/CCND3/CALM2/PRKCZ/RHOA/CKS1B/HMGB1/IGF2 19 GO:1904029 regulation of cyclin-dependent protein kinase activity 7/580 98/18722 0.0325512430466616 0.146701387025216 EGFR/CCNL1/SERTAD1/NR2F2/CDKN1C/CCND3/CKS1B 7 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 7/580 98/18722 0.0325512430466616 0.146701387025216 TPT1/HSPA1A/ENO1/PPIA/MIF/XBP1/GPX1 7 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 20/580 412/18722 0.0326336455471629 0.146930382807217 HSP90B1/HSPA5/UFL1/NHLRC3/HSPA1A/DDIT3/DDB1/OS9/HECTD1/SIAH1/DNAJB14/NEMF/CAV1/PSMD1/CCDC47/CANX/SIAH2/EIF3H/UBXN4/ANAPC11 20 GO:0060326 cell chemotaxis 16/580 310/18722 0.0327354667771168 0.146966331179208 CSF3R/PLEC/MET/DUSP1/BSG/TPBG/DPP4/JAM3/PPIA/TMSB4X/MIF/LGMN/NINJ1/S100A9/HMGB1/HMGB2 16 GO:0006469 negative regulation of protein kinase activity 12/580 212/18722 0.0329484618279451 0.146966331179208 GADD45B/PLEC/DUSP1/LRP5/GNAQ/HMGCR/NPM1/NR2F2/PPIA/BMP7/CAV1/CDKN1C 12 GO:0071772 response to BMP 10/580 165/18722 0.0330118707587199 0.146966331179208 FBN1/LRP2/SPINT1/EGR1/CRIM1/TGFBR3/SPINT2/GPC3/BMP7/FSTL1 10 GO:0071773 cellular response to BMP stimulus 10/580 165/18722 0.0330118707587199 0.146966331179208 FBN1/LRP2/SPINT1/EGR1/CRIM1/TGFBR3/SPINT2/GPC3/BMP7/FSTL1 10 GO:0003283 atrial septum development 3/580 23/18722 0.033052415053419 0.146966331179208 SOX4/GJA5/ISL1 3 GO:0021871 forebrain regionalization 3/580 23/18722 0.033052415053419 0.146966331179208 ADGRG1/GLI3/TRA2B 3 GO:0030325 adrenal gland development 3/580 23/18722 0.033052415053419 0.146966331179208 PBX1/CITED2/ARID5B 3 GO:0030539 male genitalia development 3/580 23/18722 0.033052415053419 0.146966331179208 LGR4/DHCR24/TBX3 3 GO:0035994 response to muscle stretch 3/580 23/18722 0.033052415053419 0.146966331179208 FOS/SLC9A1/NFKBIA 3 GO:0042026 protein refolding 3/580 23/18722 0.033052415053419 0.146966331179208 HSPA5/HSPA1A/HSPA8 3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process 3/580 23/18722 0.033052415053419 0.146966331179208 CHPF/CHST12/B3GAT3 3 GO:0071636 positive regulation of transforming growth factor beta production 3/580 23/18722 0.033052415053419 0.146966331179208 CD46/FERMT1/ATP6AP2 3 GO:1900273 positive regulation of long-term synaptic potentiation 3/580 23/18722 0.033052415053419 0.146966331179208 APP/EIF2AK4/LGMN 3 GO:0007052 mitotic spindle organization 8/580 120/18722 0.033165309657688 0.147046573134325 DYNC1H1/HSPA1A/TACC2/TPR/RHOA/RAN/STMN1/RAB11A 8 GO:0032411 positive regulation of transporter activity 8/580 120/18722 0.033165309657688 0.147046573134325 AKAP9/TCAF1/SLC9A1/CALM1/KIF5B/GSTO1/TMSB4X/CALM2 8 GO:0048593 camera-type eye morphogenesis 8/580 120/18722 0.033165309657688 0.147046573134325 TENM3/NAGLU/LRP5/FAT1/GLI3/CITED2/BMP7/TFAP2A 8 GO:0032387 negative regulation of intracellular transport 5/580 58/18722 0.0334555044219986 0.147910219645167 LMAN1/FERMT1/OS9/TPR/TXN 5 GO:0035904 aorta development 5/580 58/18722 0.0334555044219986 0.147910219645167 LRP2/LRP1/ADAMTS6/SOX4/HECTD1 5 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 5/580 58/18722 0.0334555044219986 0.147910219645167 DDIT3/PMAIP1/SIAH1/CAV1/S100A9 5 GO:0019318 hexose metabolic process 13/580 237/18722 0.0338152212558582 0.149207898807674 GAPDH/GAA/ALDOA/ENO1/LRP5/DDB1/PMAIP1/FUCA1/TPI1/PHLDA2/PGP/HMGB1/IGF2 13 GO:0008306 associative learning 6/580 78/18722 0.0338773470524412 0.149207898807674 FOS/APP/ITGB1/TPBG/HMGCR/LGMN 6 GO:0030500 regulation of bone mineralization 6/580 78/18722 0.0338773470524412 0.149207898807674 FBN2/ATP2B1/NOTUM/BMP7/TFAP2A/ATRAID 6 GO:0034637 cellular carbohydrate biosynthetic process 6/580 78/18722 0.0338773470524412 0.149207898807674 ISYNA1/AGL/PTGES3/PGP/IGF2/UGP2 6 GO:0001558 regulation of cell growth 20/580 414/18722 0.0340683125797971 0.149754902125269 LRP1/EGFR/GOLGA4/MACF1/SEMA6A/SEMA6D/HSPA1A/ENO1/GJA1/SLC9A1/BTG1/RTN4/NPM1/VGLL4/EIF4G1/S100A9/RHOA/CDC42/CYBA/RAB11A 20 GO:0062013 positive regulation of small molecule metabolic process 9/580 143/18722 0.0340910368042258 0.149754902125269 APP/ENO1/DDB1/ADM/POR/PMAIP1/TMSB4X/HMGB1/IGF2 9 GO:0006165 nucleoside diphosphate phosphorylation 7/580 99/18722 0.0341324805490618 0.149754902125269 GAPDH/LDHA/APP/ALDOA/ENO1/TPI1/PKM 7 GO:0110149 regulation of biomineralization 7/580 99/18722 0.0341324805490618 0.149754902125269 FBN2/ATP2B1/ROCK1/NOTUM/BMP7/TFAP2A/ATRAID 7 GO:0007265 Ras protein signal transduction 17/580 337/18722 0.0341625351870373 0.149754902125269 JUN/RHOB/ADGRG1/ITGB1/KANK1/MET/DHCR24/ROCK1/HACD3/CFL1/WASF2/RASA1/RHOA/STMN1/CDC42/DYNLT1/CTNNAL1 17 GO:0043001 Golgi to plasma membrane protein transport 4/580 40/18722 0.0345585194375189 0.150921759534179 GOLGA4/MACF1/SPTBN1/VAMP2 4 GO:0045777 positive regulation of blood pressure 4/580 40/18722 0.0345585194375189 0.150921759534179 ADRB1/NR2F2/RHOA/CYBA 4 GO:0060412 ventricular septum morphogenesis 4/580 40/18722 0.0345585194375189 0.150921759534179 TGFBR3/SOX4/TBX3/CITED2 4 GO:0071526 semaphorin-plexin signaling pathway 4/580 40/18722 0.0345585194375189 0.150921759534179 NRP2/SEMA6A/SEMA6D/MET 4 GO:0009755 hormone-mediated signaling pathway 11/580 190/18722 0.0348762565169796 0.152166481295002 LGR5/LGR4/UFL1/ISL1/ESRRA/PRLR/BMP7/PTGES3/RHOA/YWHAH/CSNK2B 11 GO:0000082 G1/S transition of mitotic cell cycle 12/580 214/18722 0.0350311554226401 0.152699066420524 EGFR/RPS6/ITGB1/SOX4/ADAMTS1/PRKDC/BRD4/CDK6/EIF4G1/CTDSPL/E2F4/CCND3 12 GO:0007612 learning 9/580 144/18722 0.0354108996469847 0.15379493970073 JUN/FOS/APP/ITGB1/TPBG/HMGCR/EIF2AK4/LGMN/VDAC1 9 GO:0033135 regulation of peptidyl-serine phosphorylation 9/580 144/18722 0.0354108996469847 0.15379493970073 AKAP9/EGFR/APP/TFRC/NSD1/EIF4G1/CAV1/MIF/TXN 9 GO:0007254 JNK cascade 10/580 167/18722 0.0354148313092843 0.15379493970073 EGFR/GADD45B/APP/IGF1R/DUSP9/HACD3/MARVELD3/GADD45G/HMGB1/CDC42 10 GO:0034767 positive regulation of ion transmembrane transport 10/580 167/18722 0.0354148313092843 0.15379493970073 AKAP9/TCAF1/KCNN4/ITGB1/SLC9A1/CALM1/KIF5B/GSTO1/TMSB4X/CALM2 10 GO:0006406 mRNA export from nucleus 5/580 59/18722 0.0356580920027071 0.154131771286795 PABPN1/THOC2/TPR/HNRNPA2B1/SRSF3 5 GO:0021885 forebrain cell migration 5/580 59/18722 0.0356580920027071 0.154131771286795 LAMB1/ADGRG1/GLI3/RTN4/RHOA 5 GO:0032768 regulation of monooxygenase activity 5/580 59/18722 0.0356580920027071 0.154131771286795 EGFR/CALM1/POR/CAV1/HM13 5 GO:0035306 positive regulation of dephosphorylation 5/580 59/18722 0.0356580920027071 0.154131771286795 SLC39A10/PPP1R15A/CALM1/PPIA/CALM2 5 GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus 5/580 59/18722 0.0356580920027071 0.154131771286795 PABPN1/THOC2/TPR/HNRNPA2B1/SRSF3 5 GO:0000245 spliceosomal complex assembly 6/580 79/18722 0.0357419074731046 0.154207431964202 SF1/SCAF11/LUC7L3/SRSF6/SRSF5/SNRPD2 6 GO:0006029 proteoglycan metabolic process 6/580 79/18722 0.0357419074731046 0.154207431964202 CHPF/EXTL2/GPC1/CHST12/B3GAT3/TCF7L2 6 GO:0015833 peptide transport 14/580 264/18722 0.0362084688907496 0.155442963417743 LRP1/EGFR/SOX4/ISL1/LRP5/GJA1/DPP4/HMGCR/KIF5B/TCF7L2/HMGN3/DYNLL1/FAM3B/PHPT1 14 GO:0002002 regulation of angiotensin levels in blood 2/580 10/18722 0.0365630191311569 0.155442963417743 ENPEP/ATP6AP2 2 GO:0002003 angiotensin maturation 2/580 10/18722 0.0365630191311569 0.155442963417743 ENPEP/ATP6AP2 2 GO:0002934 desmosome organization 2/580 10/18722 0.0365630191311569 0.155442963417743 DSG2/DSP 2 GO:0003056 regulation of vascular associated smooth muscle contraction 2/580 10/18722 0.0365630191311569 0.155442963417743 ATP2B1/RHOA 2 GO:0003163 sinoatrial node development 2/580 10/18722 0.0365630191311569 0.155442963417743 ISL1/TBX3 2 GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation 2/580 10/18722 0.0365630191311569 0.155442963417743 NPM1/EIF2AK4 2 GO:0016139 glycoside catabolic process 2/580 10/18722 0.0365630191311569 0.155442963417743 GUSB/FUCA1 2 GO:0036363 transforming growth factor beta activation 2/580 10/18722 0.0365630191311569 0.155442963417743 ITGAV/LTBP1 2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence 2/580 10/18722 0.0365630191311569 0.155442963417743 EMC1/EMC10 2 GO:0050861 positive regulation of B cell receptor signaling pathway 2/580 10/18722 0.0365630191311569 0.155442963417743 SLC39A10/CD81 2 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 2/580 10/18722 0.0365630191311569 0.155442963417743 CALM1/CALM2 2 GO:0051409 response to nitrosative stress 2/580 10/18722 0.0365630191311569 0.155442963417743 DUSP6/DDIT3 2 GO:0072124 regulation of glomerular mesangial cell proliferation 2/580 10/18722 0.0365630191311569 0.155442963417743 EGR1/BMP7 2 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 2/580 10/18722 0.0365630191311569 0.155442963417743 DDIT3/PMAIP1 2 GO:2000674 regulation of type B pancreatic cell apoptotic process 2/580 10/18722 0.0365630191311569 0.155442963417743 TCF7L2/SRSF6 2 GO:0061351 neural precursor cell proliferation 9/580 145/18722 0.0367654488727358 0.15557740538232 LRP2/SPINT1/ADGRG1/SPINT2/GLI3/SLC6A4/ASPM/GNAI2/RHOA 9 GO:0002726 positive regulation of T cell cytokine production 3/580 24/18722 0.0369291454616387 0.15557740538232 CD81/CD55/PRKCZ 3 GO:0003148 outflow tract septum morphogenesis 3/580 24/18722 0.0369291454616387 0.15557740538232 LRP2/NRP2/ISL1 3 GO:0016486 peptide hormone processing 3/580 24/18722 0.0369291454616387 0.15557740538232 CTSL/ENPEP/ATP6AP2 3 GO:0032928 regulation of superoxide anion generation 3/580 24/18722 0.0369291454616387 0.15557740538232 EGFR/GNAI2/CYBA 3 GO:0051647 nucleus localization 3/580 24/18722 0.0369291454616387 0.15557740538232 DYNC1H1/SYNE2/CDC42 3 GO:0061162 establishment of monopolar cell polarity 3/580 24/18722 0.0369291454616387 0.15557740538232 FAT1/RHOA/CDC42 3 GO:0071577 zinc ion transmembrane transport 3/580 24/18722 0.0369291454616387 0.15557740538232 SLC39A10/SLC39A7/SLC39A1 3 GO:0120255 olefinic compound biosynthetic process 3/580 24/18722 0.0369291454616387 0.15557740538232 EGR1/ADM/HSD17B1 3 GO:2001026 regulation of endothelial cell chemotaxis 3/580 24/18722 0.0369291454616387 0.15557740538232 MET/TMSB4X/LGMN 3 GO:0010907 positive regulation of glucose metabolic process 4/580 41/18722 0.0373896359928046 0.157327892262334 DDB1/PMAIP1/HMGB1/IGF2 4 GO:0042102 positive regulation of T cell proliferation 7/580 101/18722 0.0374461356126431 0.157327892262334 CD46/TFRC/CD81/IL6ST/CD55/HMGB1/IGF2 7 GO:0046939 nucleotide phosphorylation 7/580 101/18722 0.0374461356126431 0.157327892262334 GAPDH/LDHA/APP/ALDOA/ENO1/TPI1/PKM 7 GO:0032204 regulation of telomere maintenance 6/580 80/18722 0.0376711647677318 0.158130493984405 PPP1R10/HNRNPA1/ATRX/HNRNPC/HNRNPD/HNRNPA2B1 6 GO:0031638 zymogen activation 5/580 60/18722 0.0379480715396924 0.15871985677258 CTSL/ENO1/DHCR24/ASPH/LGMN 5 GO:0051851 modulation by host of symbiont process 5/580 60/18722 0.0379480715396924 0.15871985677258 JUN/EIF2AK4/CFL1/STOM/HSPA8 5 GO:0060038 cardiac muscle cell proliferation 5/580 60/18722 0.0379480715396924 0.15871985677258 TGFBR3/GJA1/CITED2/VGLL4/CDK1 5 GO:0061951 establishment of protein localization to plasma membrane 5/580 60/18722 0.0379480715396924 0.15871985677258 GOLGA4/MACF1/SPTBN1/VAMP2/RAB11A 5 GO:0045765 regulation of angiogenesis 17/580 342/18722 0.0384201065544396 0.160549789384275 COL4A2/GRN/RHOB/SEMA6A/ITGB1/SERPINF1/ISL1/ADAMTS1/BTG1/ADM/ROCK1/EMC10/PKM/XBP1/MYDGF/NINJ1/HMGB1 17 GO:1903320 regulation of protein modification by small protein conjugation or removal 13/580 242/18722 0.0389656189181505 0.162683207888975 RPS20/HSPA5/EGR1/UFL1/RPL23/SOX4/MYCBP2/HSPA1A/NPM1/PPIA/CAV1/SIAH2/UBE2L3 13 GO:0097237 cellular response to toxic substance 8/580 124/18722 0.039123256171826 0.163194856013599 MGST3/SOD3/BMP7/GSTO1/TXN/GPX3/S100A9/GPX1 8 GO:1902749 regulation of cell cycle G2/M phase transition 7/580 102/18722 0.0391795393745159 0.163283187841284 APP/PBX1/NPM1/CENPF/BRD4/CDK1/RAB11A 7 GO:0050900 leukocyte migration 18/580 369/18722 0.0395324188076322 0.16460633829391 CSF3R/APP/ITGB1/PLEC/DUSP1/BSG/DPP4/ROCK1/JAM3/CD81/PPIA/MIF/LGMN/NINJ1/S100A9/RHOA/HMGB1/CDC42 18 GO:1903533 regulation of protein targeting 6/580 81/18722 0.0396656758459035 0.165013469015471 TCAF1/LMAN1/NUCB1/STOM/LEPROT/UBE2L3 6 GO:0016358 dendrite development 13/580 243/18722 0.0400589103962365 0.166500439904286 APP/ITGB1/IQGAP1/TPBG/DLG5/CUX1/BMP7/CFL1/ID1/RHOA/YWHAH/CDC42/DYNLT1 13 GO:0006816 calcium ion transport 20/580 422/18722 0.0402787347838605 0.166816185195511 TPT1/ATP2B1/AHNAK/ITGAV/KCNN4/SLC3A2/GJA1/SLC9A1/DDIT3/DIAPH1/CALM1/C4orf3/GSTO1/CAV1/GNAI2/CALM2/RHOA/VDAC1/YWHAE/CYBA 20 GO:0042255 ribosome assembly 5/580 61/18722 0.040326024056961 0.166816185195511 RPLP0/RPL23A/RPL6/PRKDC/NPM1 5 GO:0090342 regulation of cell aging 5/580 61/18722 0.040326024056961 0.166816185195511 YBX1/PRKDC/YPEL3/CDK6/MIF 5 GO:0030890 positive regulation of B cell proliferation 4/580 42/18722 0.0403500770468609 0.166816185195511 SLC39A10/TFRC/CD81/MIF 4 GO:0045773 positive regulation of axon extension 4/580 42/18722 0.0403500770468609 0.166816185195511 LRP1/GOLGA4/MACF1/RAB11A 4 GO:0090317 negative regulation of intracellular protein transport 4/580 42/18722 0.0403500770468609 0.166816185195511 LMAN1/FERMT1/OS9/TXN 4 GO:0030833 regulation of actin filament polymerization 10/580 171/18722 0.0405805160229378 0.166999018349801 IQGAP2/KANK1/SPTAN1/SPTBN1/TMSB4X/WASF2/TRIOBP/PFN1/RASA1/RHOA 10 GO:0009135 purine nucleoside diphosphate metabolic process 7/580 103/18722 0.0409646042937518 0.166999018349801 GAPDH/LDHA/APP/ALDOA/ENO1/TPI1/PKM 7 GO:0009179 purine ribonucleoside diphosphate metabolic process 7/580 103/18722 0.0409646042937518 0.166999018349801 GAPDH/LDHA/APP/ALDOA/ENO1/TPI1/PKM 7 GO:0019395 fatty acid oxidation 7/580 103/18722 0.0409646042937518 0.166999018349801 ILVBL/SLC27A2/POR/CROT/ECHDC2/ACADVL/HADHA 7 GO:0003094 glomerular filtration 3/580 25/18722 0.0410277986026077 0.166999018349801 GJA5/GJA1/CYBA 3 GO:0010447 response to acidic pH 3/580 25/18722 0.0410277986026077 0.166999018349801 SERPINF1/SLC9A1/LGMN 3 GO:0015012 heparan sulfate proteoglycan biosynthetic process 3/580 25/18722 0.0410277986026077 0.166999018349801 EXTL2/B3GAT3/TCF7L2 3 GO:0048596 embryonic camera-type eye morphogenesis 3/580 25/18722 0.0410277986026077 0.166999018349801 CITED2/BMP7/TFAP2A 3 GO:0061339 establishment or maintenance of monopolar cell polarity 3/580 25/18722 0.0410277986026077 0.166999018349801 FAT1/RHOA/CDC42 3 GO:0090169 regulation of spindle assembly 3/580 25/18722 0.0410277986026077 0.166999018349801 DYNC1H1/HSPA1A/TPR 3 GO:0140448 signaling receptor ligand precursor processing 3/580 25/18722 0.0410277986026077 0.166999018349801 CTSL/ENPEP/ATP6AP2 3 GO:1901798 positive regulation of signal transduction by p53 class mediator 3/580 25/18722 0.0410277986026077 0.166999018349801 RPS20/RPL23/PMAIP1 3 GO:1903792 negative regulation of anion transport 3/580 25/18722 0.0410277986026077 0.166999018349801 GABRE/SLC43A2/ARL6IP5 3 GO:1904385 cellular response to angiotensin 3/580 25/18722 0.0410277986026077 0.166999018349801 ROCK1/CAV1/CYBA 3 GO:1904754 positive regulation of vascular associated smooth muscle cell migration 3/580 25/18722 0.0410277986026077 0.166999018349801 LRP1/IQGAP1/ADAMTS1 3 GO:1905048 regulation of metallopeptidase activity 3/580 25/18722 0.0410277986026077 0.166999018349801 LRP1/CLDN4/TIMP3 3 GO:0044839 cell cycle G2/M phase transition 9/580 148/18722 0.0410406101857283 0.166999018349801 APP/PBX1/CALM1/NPM1/CENPF/BRD4/CALM2/CDK1/RAB11A 9 GO:0070507 regulation of microtubule cytoskeleton organization 9/580 148/18722 0.0410406101857283 0.166999018349801 AKAP9/DYNC1H1/CLIP1/MET/HSPA1A/ROCK1/TPR/RHOA/STMN1 9 GO:0009895 negative regulation of catabolic process 16/580 320/18722 0.0417602721691675 0.169778868757691 EGFR/RPL23/MET/MYCBP2/CTSA/YBX1/ROCK1/HMGCR/EIF4G1/FUS/TIMP3/EIF3H/ATRAID/HNRNPC/HNRNPD/CIRBP 16 GO:0007219 Notch signaling pathway 10/580 172/18722 0.0419485462102954 0.170395361069069 AAK1/APP/CD46/KRT19/NCSTN/GALNT11/BMP7/IL6ST/NFKBIA/ANXA4 10 GO:0006006 glucose metabolic process 11/580 196/18722 0.0421450947368027 0.171044359180514 GAPDH/GAA/ENO1/LRP5/DDB1/PMAIP1/TPI1/PHLDA2/PGP/HMGB1/IGF2 11 GO:0032874 positive regulation of stress-activated MAPK cascade 8/580 126/18722 0.0423542117123716 0.171743189777019 GADD45B/APP/HMGCR/EMC10/GADD45G/ARL6IP5/HMGB1/CDC42 8 GO:0032835 glomerulus development 5/580 62/18722 0.0427924368898667 0.172297899345239 EGR1/LGR4/IQGAP1/ENPEP/BMP7 5 GO:0048488 synaptic vesicle endocytosis 5/580 62/18722 0.0427924368898667 0.172297899345239 ROCK1/CALM1/VAMP2/ACTG1/CANX 5 GO:0140238 presynaptic endocytosis 5/580 62/18722 0.0427924368898667 0.172297899345239 ROCK1/CALM1/VAMP2/ACTG1/CANX 5 GO:0045621 positive regulation of lymphocyte differentiation 7/580 104/18722 0.0428017521345567 0.172297899345239 CD46/SOX4/GLI3/PRKDC/XBP1/PRKCZ/RHOA 7 GO:0060419 heart growth 7/580 104/18722 0.0428017521345567 0.172297899345239 TGFBR3/DUSP6/GJA1/DUSP9/CITED2/VGLL4/CDK1 7 GO:0006694 steroid biosynthetic process 10/580 173/18722 0.0433477542655315 0.172297899345239 EGR1/DHCR24/SF1/PBX1/ADM/HMGCR/SLC27A2/POR/PRLR/HSD17B1 10 GO:0009268 response to pH 4/580 43/18722 0.0434399368220088 0.172297899345239 SERPINF1/GJA1/SLC9A1/LGMN 4 GO:0031952 regulation of protein autophosphorylation 4/580 43/18722 0.0434399368220088 0.172297899345239 IQGAP1/CALM1/CAV1/CALM2 4 GO:0042181 ketone biosynthetic process 4/580 43/18722 0.0434399368220088 0.172297899345239 EGR1/ADM/TPI1/HSD17B1 4 GO:0045840 positive regulation of mitotic nuclear division 4/580 43/18722 0.0434399368220088 0.172297899345239 LRP5/PHIP/IGF2/ANAPC11 4 GO:0060443 mammary gland morphogenesis 4/580 43/18722 0.0434399368220088 0.172297899345239 LRP5/GLI3/TBX3/CAV1 4 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 2/580 11/18722 0.0437875977265259 0.172297899345239 CD46/CD55 2 GO:0003139 secondary heart field specification 2/580 11/18722 0.0437875977265259 0.172297899345239 LRP2/ISL1 2 GO:0003174 mitral valve development 2/580 11/18722 0.0437875977265259 0.172297899345239 SOX4/GJA5 2 GO:0007042 lysosomal lumen acidification 2/580 11/18722 0.0437875977265259 0.172297899345239 GRN/ATP6AP2 2 GO:0009313 oligosaccharide catabolic process 2/580 11/18722 0.0437875977265259 0.172297899345239 MANBA/NEU1 2 GO:0019372 lipoxygenase pathway 2/580 11/18722 0.0437875977265259 0.172297899345239 GPX1/HPGD 2 GO:0032329 serine transport 2/580 11/18722 0.0437875977265259 0.172297899345239 SLC38A2/SLC1A5 2 GO:0033690 positive regulation of osteoblast proliferation 2/580 11/18722 0.0437875977265259 0.172297899345239 ITGAV/LRP5 2 GO:0033860 regulation of NAD(P)H oxidase activity 2/580 11/18722 0.0437875977265259 0.172297899345239 GNAI2/CYBA 2 GO:0034163 regulation of toll-like receptor 9 signaling pathway 2/580 11/18722 0.0437875977265259 0.172297899345239 RTN4/HMGB1 2 GO:0043589 skin morphogenesis 2/580 11/18722 0.0437875977265259 0.172297899345239 ITGB4/ITGA6 2 GO:0045657 positive regulation of monocyte differentiation 2/580 11/18722 0.0437875977265259 0.172297899345239 JUN/ZFP36L1 2 GO:0048680 positive regulation of axon regeneration 2/580 11/18722 0.0437875977265259 0.172297899345239 LRP1/GRN 2 GO:0072110 glomerular mesangial cell proliferation 2/580 11/18722 0.0437875977265259 0.172297899345239 EGR1/BMP7 2 GO:0090084 negative regulation of inclusion body assembly 2/580 11/18722 0.0437875977265259 0.172297899345239 HSPA1A/DNAJB1 2 GO:0097050 type B pancreatic cell apoptotic process 2/580 11/18722 0.0437875977265259 0.172297899345239 TCF7L2/SRSF6 2 GO:0098935 dendritic transport 2/580 11/18722 0.0437875977265259 0.172297899345239 PURA/KIF5B 2 GO:1900222 negative regulation of amyloid-beta clearance 2/580 11/18722 0.0437875977265259 0.172297899345239 LRPAP1/HMGCR 2 GO:1900426 positive regulation of defense response to bacterium 2/580 11/18722 0.0437875977265259 0.172297899345239 GRN/CYBA 2 GO:1902065 response to L-glutamate 2/580 11/18722 0.0437875977265259 0.172297899345239 UFL1/PCNA 2 GO:1903897 regulation of PERK-mediated unfolded protein response 2/580 11/18722 0.0437875977265259 0.172297899345239 HSPA5/PPP1R15A 2 GO:1903961 positive regulation of anion transmembrane transport 2/580 11/18722 0.0437875977265259 0.172297899345239 TCAF1/ITGB1 2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 2/580 11/18722 0.0437875977265259 0.172297899345239 HSPA5/DDIT3 2 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 2/580 11/18722 0.0437875977265259 0.172297899345239 LRP1/HMGB1 2 GO:0050886 endocrine process 6/580 83/18722 0.0438524415195154 0.172407189777909 ENPEP/GJA1/TBX3/ATP6AP2/RHOA/CYBA 6 GO:0070665 positive regulation of leukocyte proliferation 9/580 150/18722 0.0440701628698111 0.173116830665111 SLC39A10/CD46/TFRC/CD81/IL6ST/MIF/CD55/HMGB1/IGF2 9 GO:0031331 positive regulation of cellular catabolic process 20/580 427/18722 0.0445589346667924 0.174889118257596 LRP2/LRP1/APP/KCNQ1OT1/UFL1/HSPA1A/ZFP36L1/CTSC/TMEM259/TNRC6A/ROCK1/HECTD1/CD81/PUM1/VGLL4/CAV1/TMEM59/HNRNPD/HMGB1/VDAC1 20 GO:0006760 folic acid-containing compound metabolic process 3/580 26/18722 0.045345370761031 0.176347970141266 FOLR1/SLC19A1/TYMS 3 GO:0010875 positive regulation of cholesterol efflux 3/580 26/18722 0.045345370761031 0.176347970141266 LRP1/CAV1/NFKBIA 3 GO:0034063 stress granule assembly 3/580 26/18722 0.045345370761031 0.176347970141266 DYNC1H1/PRRC2C/CIRBP 3 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 3/580 26/18722 0.045345370761031 0.176347970141266 SLC39A10/KCNN4/CD81 3 GO:0051350 negative regulation of lyase activity 3/580 26/18722 0.045345370761031 0.176347970141266 AKAP9/GNAI2/PHPT1 3 GO:0060037 pharyngeal system development 3/580 26/18722 0.045345370761031 0.176347970141266 ISL1/FOLR1/BMP7 3 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 3/580 26/18722 0.045345370761031 0.176347970141266 CALM1/GSTO1/CALM2 3 GO:0097205 renal filtration 3/580 26/18722 0.045345370761031 0.176347970141266 GJA5/GJA1/CYBA 3 GO:0022617 extracellular matrix disassembly 5/580 63/18722 0.0453477042117725 0.176347970141266 LRP1/LAMC1/MMP15/CTSV/DPP4 5 GO:0030239 myofibril assembly 5/580 63/18722 0.0453477042117725 0.176347970141266 KRT19/ITGB1/PLEC/ACTG1/KRT8 5 GO:1902373 negative regulation of mRNA catabolic process 5/580 63/18722 0.0453477042117725 0.176347970141266 YBX1/FUS/HNRNPC/HNRNPD/CIRBP 5 GO:0050920 regulation of chemotaxis 12/580 223/18722 0.0455658725771994 0.177048348668801 SEMA6A/SEMA6D/MET/DUSP1/MYCBP2/TPBG/DPP4/JAM3/TMSB4X/MIF/LGMN/HMGB1 12 GO:0071456 cellular response to hypoxia 9/580 151/18722 0.0456396622450263 0.177187035977978 MALAT1/EGR1/P4HB/ENO1/ZFP36L1/SLC9A1/PMAIP1/CITED2/BMP7 9 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 8/580 128/18722 0.0457570432645505 0.177494585674249 GADD45B/APP/HMGCR/EMC10/GADD45G/ARL6IP5/HMGB1/CDC42 8 GO:0021537 telencephalon development 13/580 248/18722 0.0458514779177696 0.177712686496289 LRP1/LAMB1/ADGRG1/SLC2A1/SLC38A2/GLI3/RTN4/TACC2/KIF5B/CDK6/ASPM/TRA2B/RHOA 13 GO:0042098 T cell proliferation 11/580 199/18722 0.0461456560711307 0.178703952029 RPS6/CD46/NCSTN/DLG5/TFRC/CD81/IL6ST/CD55/CCND3/HMGB1/IGF2 11 GO:0009185 ribonucleoside diphosphate metabolic process 7/580 106/18722 0.046633837071465 0.179794129684976 GAPDH/LDHA/APP/ALDOA/ENO1/TPI1/PKM 7 GO:0005978 glycogen biosynthetic process 4/580 44/18722 0.0466591086927039 0.179794129684976 AGL/PTGES3/IGF2/UGP2 4 GO:0009250 glucan biosynthetic process 4/580 44/18722 0.0466591086927039 0.179794129684976 AGL/PTGES3/IGF2/UGP2 4 GO:0021517 ventral spinal cord development 4/580 44/18722 0.0466591086927039 0.179794129684976 SOX4/ISL1/GLI3/LMO4 4 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 4/580 44/18722 0.0466591086927039 0.179794129684976 FAT1/DLG5/RHOA/CDC42 4 GO:0097178 ruffle assembly 4/580 44/18722 0.0466591086927039 0.179794129684976 KANK1/TACSTD2/CAV1/PFN1 4 GO:0046883 regulation of hormone secretion 13/580 249/18722 0.0470764122553926 0.181251981291251 LRP1/EGFR/SOX4/ISL1/LRP5/GJA1/DPP4/HMGCR/KIF5B/TCF7L2/HMGN3/DYNLL1/PHPT1 13 GO:0007498 mesoderm development 8/580 129/18722 0.0475237185617065 0.182822841216292 ITGB4/ITGB1/WLS/ZFP36L1/GJA1/TBX3/CITED2/BMP7 8 GO:0018212 peptidyl-tyrosine modification 18/580 378/18722 0.0479661528265532 0.184015981959402 EGFR/EFEMP1/APP/MET/IQGAP1/ISL1/TPST2/EPHB4/ERBB3/IGF1R/CSH1/CD81/PRLR/CAV1/IL6ST/MIF/PRKCZ/IGF2 18 GO:0006749 glutathione metabolic process 5/580 64/18722 0.0479921277395731 0.184015981959402 PTGES2/GSTO1/ARL6IP5/GPX1/CLIC3 5 GO:0030104 water homeostasis 5/580 64/18722 0.0479921277395731 0.184015981959402 CLDN4/PLEC/MET/LSR/STMN1 5 GO:0055002 striated muscle cell development 5/580 64/18722 0.0479921277395731 0.184015981959402 KRT19/ITGB1/PLEC/ACTG1/KRT8 5 GO:0043270 positive regulation of ion transport 14/580 275/18722 0.0481020821359001 0.184285654047835 ATP2B1/AKAP9/TCAF1/KCNN4/ITGB1/SLC9A1/CALM1/KIF5B/SLC6A4/GSTO1/CAV1/TMSB4X/PRSS8/CALM2 14 GO:0060021 roof of mouth development 6/580 85/18722 0.0483056736417674 0.184761256667648 FRAS1/TGFBR3/GLI3/TBX3/ARID5B/TFAP2A 6 GO:0072384 organelle transport along microtubule 6/580 85/18722 0.0483056736417674 0.184761256667648 ARMCX3/DYNC1H1/KIF5B/ARHGAP21/PRKCZ/CDC42 6 GO:0051341 regulation of oxidoreductase activity 7/580 107/18722 0.0486294701730975 0.185846890530055 EGFR/CALM1/POR/CAV1/HM13/GNAI2/CYBA 7 GO:0009952 anterior/posterior pattern specification 11/580 201/18722 0.048952320202751 0.186927127473723 WLS/BPTF/LRP5/PBX1/GLI3/DDIT3/PRKDC/TBX3/GPC3/ATP6AP2/NR2F2 11 GO:0031346 positive regulation of cell projection organization 17/580 353/18722 0.0491206792258252 0.187416143625359 LRP1/GRN/TENM3/HSPA5/GOLGA4/MACF1/ITGA6/SERPINF1/IQGAP1/CUX1/BMP7/WASF2/PFN1/S100A9/CDC42/DYNLT1/RAB11A 17 GO:0051028 mRNA transport 8/580 130/18722 0.0493342915357485 0.188076876994071 ZFP36L1/HNRNPA1/PABPN1/THOC2/TPR/HNRNPA2B1/HNRNPA3/SRSF3 8 GO:0006486 protein glycosylation 12/580 226/18722 0.049517263126715 0.188465458921728 RPN2/EXTL2/B3GAT3/DDOST/TRIP11/C1GALT1/GALNT11/MAN1A2/MGAT1/MPDU1/TMEM59/TUSC3 12 GO:0043413 macromolecule glycosylation 12/580 226/18722 0.049517263126715 0.188465458921728 RPN2/EXTL2/B3GAT3/DDOST/TRIP11/C1GALT1/GALNT11/MAN1A2/MGAT1/MPDU1/TMEM59/TUSC3 12 GO:0072503 cellular divalent inorganic cation homeostasis 22/580 486/18722 0.0496542408023226 0.188632532989749 TPT1/ATP2B1/LRP1/HSP90B1/SLC39A10/ITGAV/APP/GJA1/DDIT3/ADM/DIAPH1/CALM1/GSTO1/CAV1/SLC39A7/CCDC47/CD55/S100A9/CALM2/HMGB1/YWHAE/CYBA 22 GO:0000027 ribosomal large subunit assembly 3/580 27/18722 0.0498783865986439 0.188632532989749 RPLP0/RPL23A/RPL6 3 GO:0031954 positive regulation of protein autophosphorylation 3/580 27/18722 0.0498783865986439 0.188632532989749 IQGAP1/CALM1/CALM2 3 GO:0032781 positive regulation of ATPase activity 3/580 27/18722 0.0498783865986439 0.188632532989749 DNAJB1/PFN1/DNAJC9 3 GO:0034698 response to gonadotropin 3/580 27/18722 0.0498783865986439 0.188632532989749 TGFBR3/CTSV/POR 3 GO:0070861 regulation of protein exit from endoplasmic reticulum 3/580 27/18722 0.0498783865986439 0.188632532989749 GCC2/OS9/CD81 3 GO:1903421 regulation of synaptic vesicle recycling 3/580 27/18722 0.0498783865986439 0.188632532989749 ROCK1/CALM1/VAMP2 3 GO:0003197 endocardial cushion development 4/580 45/18722 0.0500072915881231 0.188632532989749 ISL1/TBX3/CITED2/BMP7 4 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 4/580 45/18722 0.0500072915881231 0.188632532989749 P4HB/PPIA/ARL6IP5/GPX1 4 GO:0030850 prostate gland development 4/580 45/18722 0.0500072915881231 0.188632532989749 SERPINF1/PSAP/GLI3/BMP7 4 GO:0048538 thymus development 4/580 45/18722 0.0500072915881231 0.188632532989749 PBX1/PRKDC/LMO4/CITED2 4 GO:0032413 negative regulation of ion transmembrane transporter activity 6/580 86/18722 0.0506330810765036 0.189010263379211 CALM1/C4orf3/GSTO1/CAV1/CALM2/YWHAE 6 GO:2001251 negative regulation of chromosome organization 6/580 86/18722 0.0506330810765036 0.189010263379211 DUSP1/HNRNPA1/ATRX/CENPF/TPR/HNRNPC 6 GO:0034440 lipid oxidation 7/580 108/18722 0.0506785776632791 0.189010263379211 ILVBL/SLC27A2/POR/CROT/ECHDC2/ACADVL/HADHA 7 GO:0006487 protein N-linked glycosylation 5/580 65/18722 0.0507259176079101 0.189010263379211 RPN2/DDOST/MGAT1/MPDU1/TUSC3 5 GO:0035418 protein localization to synapse 5/580 65/18722 0.0507259176079101 0.189010263379211 DAG1/KIF5B/VAMP2/PRKCZ/RAB11A 5 GO:0043489 RNA stabilization 5/580 65/18722 0.0507259176079101 0.189010263379211 YBX1/FUS/HNRNPC/HNRNPD/CIRBP 5 GO:1905330 regulation of morphogenesis of an epithelium 5/580 65/18722 0.0507259176079101 0.189010263379211 LGR4/GJA1/TACSTD2/MAGED1/BMP7 5 GO:0061448 connective tissue development 13/580 252/18722 0.0508869546275856 0.189010263379211 GLG1/EFEMP1/EGR1/SERPINH1/LRP5/ESRRA/GLI3/TRIP11/POR/BMP7/ARID5B/XBP1/TYMS 13 GO:0007162 negative regulation of cell adhesion 15/580 303/18722 0.0510683633489767 0.189010263379211 LRP1/FBLN1/SEMA6A/CDH1/KANK1/SPINT2/DUSP1/ERBB3/GLI3/TACSTD2/DLG5/JAM3/RASA1/RHOA/HMGB1 15 GO:0002328 pro-B cell differentiation 2/580 12/18722 0.0514891429158161 0.189010263379211 SOX4/PRKDC 2 GO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane 2/580 12/18722 0.0514891429158161 0.189010263379211 HSPA5/SEC62 2 GO:0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process 2/580 12/18722 0.0514891429158161 0.189010263379211 DUT/TYMS 2 GO:0009265 2'-deoxyribonucleotide biosynthetic process 2/580 12/18722 0.0514891429158161 0.189010263379211 DUT/TYMS 2 GO:0021559 trigeminal nerve development 2/580 12/18722 0.0514891429158161 0.189010263379211 ISL1/TFAP2A 2 GO:0021978 telencephalon regionalization 2/580 12/18722 0.0514891429158161 0.189010263379211 ADGRG1/TRA2B 2 GO:0031453 positive regulation of heterochromatin assembly 2/580 12/18722 0.0514891429158161 0.189010263379211 TPR/MPHOSPH8 2 GO:0034086 maintenance of sister chromatid cohesion 2/580 12/18722 0.0514891429158161 0.189010263379211 ATRX/NIPBL 2 GO:0034088 maintenance of mitotic sister chromatid cohesion 2/580 12/18722 0.0514891429158161 0.189010263379211 ATRX/NIPBL 2 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway 2/580 12/18722 0.0514891429158161 0.189010263379211 NINJ1/HMGB1 2 GO:0034333 adherens junction assembly 2/580 12/18722 0.0514891429158161 0.189010263379211 DLG5/JAM3 2 GO:0035739 CD4-positive, alpha-beta T cell proliferation 2/580 12/18722 0.0514891429158161 0.189010263379211 CD81/CD55 2 GO:0045916 negative regulation of complement activation 2/580 12/18722 0.0514891429158161 0.189010263379211 CD46/CD55 2 GO:0046385 deoxyribose phosphate biosynthetic process 2/580 12/18722 0.0514891429158161 0.189010263379211 DUT/TYMS 2 GO:0048548 regulation of pinocytosis 2/580 12/18722 0.0514891429158161 0.189010263379211 CAV1/CDC42 2 GO:0060019 radial glial cell differentiation 2/580 12/18722 0.0514891429158161 0.189010263379211 GLI3/RHOA 2 GO:0070572 positive regulation of neuron projection regeneration 2/580 12/18722 0.0514891429158161 0.189010263379211 LRP1/GRN 2 GO:0071287 cellular response to manganese ion 2/580 12/18722 0.0514891429158161 0.189010263379211 HSPA5/APP 2 GO:0072520 seminiferous tubule development 2/580 12/18722 0.0514891429158161 0.189010263379211 ADGRG1/ATRX 2 GO:0098974 postsynaptic actin cytoskeleton organization 2/580 12/18722 0.0514891429158161 0.189010263379211 WASF2/ACTG1 2 GO:0120263 positive regulation of heterochromatin organization 2/580 12/18722 0.0514891429158161 0.189010263379211 TPR/MPHOSPH8 2 GO:1903332 regulation of protein folding 2/580 12/18722 0.0514891429158161 0.189010263379211 GRN/HSPA5 2 GO:1904667 negative regulation of ubiquitin protein ligase activity 2/580 12/18722 0.0514891429158161 0.189010263379211 RPS20/RPL23 2 GO:2000561 regulation of CD4-positive, alpha-beta T cell proliferation 2/580 12/18722 0.0514891429158161 0.189010263379211 CD81/CD55 2 GO:2001204 regulation of osteoclast development 2/580 12/18722 0.0514891429158161 0.189010263379211 FBN1/ATP6AP1 2 GO:0006401 RNA catabolic process 14/580 278/18722 0.0517694182491725 0.189889246275159 KCNQ1OT1/HSPA1A/ZFP36L1/TNRC6A/YBX1/ROCK1/NPM1/PUM1/FUS/HNRNPC/HNRNPD/CIRBP/CARHSP1/SERBP1 14 GO:0060541 respiratory system development 11/580 203/18722 0.0518725167902214 0.190117474855256 LAMA5/EGFR/DAG1/GLI3/DLG5/GPC3/MAN1A2/SRSF6/PTGES3/HMGB1/CDC42 11 GO:1903364 positive regulation of cellular protein catabolic process 9/580 155/18722 0.0522886386531868 0.191491699508639 LRP2/LRP1/HSPA1A/CTSC/TMEM259/HECTD1/CD81/VGLL4/CAV1 9 GO:0001936 regulation of endothelial cell proliferation 10/580 179/18722 0.0524111662736352 0.191789405459227 NRP2/GJA1/NR2F2/EMC10/CAV1/MYDGF/HMGB1/IGF2/HMGB2/CYBA 10 GO:0002696 positive regulation of leukocyte activation 19/580 409/18722 0.0526888017521547 0.192653786909805 JUND/SLC39A10/CD46/SOX4/CTSC/GLI3/PRKDC/DPP4/TFRC/CD81/CAV1/IL6ST/MIF/XBP1/CD55/PRKCZ/RHOA/HMGB1/IGF2 19 GO:0006821 chloride transport 7/580 109/18722 0.0527814321502454 0.192689514074404 SLC26A2/CLDN4/GABRE/SLC12A9/PCYOX1/FXYD3/CLIC3 7 GO:0043266 regulation of potassium ion transport 7/580 109/18722 0.0527814321502454 0.192689514074404 AKAP9/KCNN4/ITGB1/KIF5B/VAMP2/CAV1/YWHAE 7 GO:0007029 endoplasmic reticulum organization 6/580 87/18722 0.0530280450552979 0.193437990237012 LMAN1/EMC1/RTN4/EMC10/CCDC47/LMAN2 6 GO:0006984 ER-nucleus signaling pathway 4/580 46/18722 0.0534839966220064 0.193517714462218 HSPA5/DDIT3/PPP1R15A/CCDC47 4 GO:0043462 regulation of ATPase activity 4/580 46/18722 0.0534839966220064 0.193517714462218 DNAJB1/PFN1/DNAJC9/CNN3 4 GO:0048701 embryonic cranial skeleton morphogenesis 4/580 46/18722 0.0534839966220064 0.193517714462218 GLI3/NIPBL/TFAP2A/SLC39A1 4 GO:0055010 ventricular cardiac muscle tissue morphogenesis 4/580 46/18722 0.0534839966220064 0.193517714462218 LRP2/TGFBR3/ISL1/DSP 4 GO:0060976 coronary vasculature development 4/580 46/18722 0.0534839966220064 0.193517714462218 LRP2/ADAMTS6/TGFBR3/GPC3 4 GO:0061462 protein localization to lysosome 4/580 46/18722 0.0534839966220064 0.193517714462218 RTN4/GCC2/CD81/HSPA8 4 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 4/580 46/18722 0.0534839966220064 0.193517714462218 EGFR/ADAMTS1/EIF4G1/CCND3 4 GO:1900271 regulation of long-term synaptic potentiation 4/580 46/18722 0.0534839966220064 0.193517714462218 APP/NCSTN/EIF2AK4/LGMN 4 GO:0045600 positive regulation of fat cell differentiation 5/580 66/18722 0.053549193402037 0.193517714462218 ZFP36L1/LRP5/BMP7/XBP1/ADIRF 5 GO:0046626 regulation of insulin receptor signaling pathway 5/580 66/18722 0.053549193402037 0.193517714462218 KANK1/GNAI2/CCND3/PRKCZ/IGF2 5 GO:0050918 positive chemotaxis 5/580 66/18722 0.053549193402037 0.193517714462218 LRP1/MET/MIF/HMGB1/HMGB2 5 GO:0050922 negative regulation of chemotaxis 5/580 66/18722 0.053549193402037 0.193517714462218 SEMA6A/SEMA6D/DUSP1/DPP4/MIF 5 GO:0015698 inorganic anion transport 10/580 180/18722 0.0540351326448648 0.194970831599121 SLC26A2/CLDN4/SLC22A11/GABRE/SLC12A9/PCYOX1/SLC13A4/FXYD3/VDAC1/CLIC3 10 GO:0071897 DNA biosynthetic process 10/580 180/18722 0.0540351326448648 0.194970831599121 DUSP1/GJA1/HNRNPA1/CENPF/PTGES3/TYMS/HNRNPC/HNRNPD/HNRNPA2B1/PCNA 10 GO:0006516 glycoprotein catabolic process 3/580 28/18722 0.054622944791826 0.196634145686364 CTSL/GPC1/MANBA 3 GO:0006829 zinc ion transport 3/580 28/18722 0.054622944791826 0.196634145686364 SLC39A10/SLC39A7/SLC39A1 3 GO:0060325 face morphogenesis 3/580 28/18722 0.054622944791826 0.196634145686364 ANKRD11/NIPBL/ARID5B 3 GO:0061387 regulation of extent of cell growth 7/580 110/18722 0.0549382757327874 0.197616334441759 LRP1/GOLGA4/MACF1/SEMA6A/SEMA6D/RTN4/RAB11A 7 GO:0046328 regulation of JNK cascade 8/580 133/18722 0.0550319866544428 0.19780044044035 EGFR/GADD45B/APP/IGF1R/MARVELD3/GADD45G/HMGB1/CDC42 8 GO:0030595 leukocyte chemotaxis 12/580 230/18722 0.0551412999197915 0.198040298013089 CSF3R/PLEC/DUSP1/BSG/DPP4/JAM3/PPIA/MIF/LGMN/NINJ1/S100A9/HMGB1 12 GO:0051052 regulation of DNA metabolic process 17/580 359/18722 0.0557722846231877 0.200082520736949 EGFR/DUSP1/PPP1R10/GJA1/HNRNPA1/PRKDC/ATRX/TFRC/NPM1/FUS/MPHOSPH8/PTGES3/HNRNPC/HNRNPD/HNRNPA2B1/HMGB1/PCNA 17 GO:0001837 epithelial to mesenchymal transition 9/580 157/18722 0.0558389834264803 0.200082520736949 DAG1/TGFBR3/ISL1/ROCK1/RTN4/TBX3/DLG5/TCF7L2/BMP7 9 GO:0007034 vacuolar transport 9/580 157/18722 0.0558389834264803 0.200082520736949 LRP1/GRN/RHOB/PSAP/HSPA1A/GCC2/HOOK2/LEPROT/HSPA8 9 GO:0046635 positive regulation of alpha-beta T cell activation 5/580 67/18722 0.0564619853394387 0.20202799747285 GLI3/CD81/CD55/PRKCZ/RHOA 5 GO:0017038 protein import 11/580 206/18722 0.0564688017017212 0.20202799747285 CDH1/RPL23/PPP1R10/GLI3/FERMT1/TPR/NFKBIA/HSPA8/RAN/TXNIP/CDK1 11 GO:0042552 myelination 8/580 134/18722 0.0570206403113907 0.203462731210687 ITGB4/DAG1/PLEC/NCSTN/GPC1/CTSC/JAM3/DEGS1 8 GO:0014911 positive regulation of smooth muscle cell migration 4/580 47/18722 0.0570885539088254 0.203462731210687 LRP1/SEMA6D/IQGAP1/ADAMTS1 4 GO:0019884 antigen processing and presentation of exogenous antigen 4/580 47/18722 0.0570885539088254 0.203462731210687 CTSL/CTSD/CTSV/LGMN 4 GO:0048512 circadian behavior 4/580 47/18722 0.0570885539088254 0.203462731210687 EGR1/NAGLU/ADRB1/ZFHX3 4 GO:1900744 regulation of p38MAPK cascade 4/580 47/18722 0.0570885539088254 0.203462731210687 GADD45B/DUSP1/EMC10/GADD45G 4 GO:0001938 positive regulation of endothelial cell proliferation 7/580 111/18722 0.0571493198649861 0.20352334356206 NRP2/EMC10/MYDGF/HMGB1/IGF2/HMGB2/CYBA 7 GO:0001819 positive regulation of cytokine production 21/580 467/18722 0.0573086224179269 0.203934508696081 GAPDH/LRP1/EGR1/APP/CD46/CADM1/HSPA1A/SPTBN1/ISL1/DDIT3/FERMT1/ATP6AP2/CD81/IL6ST/MIF/XBP1/CD55/PRKCZ/HMGB1/HMGB2/CYBA 21 GO:0060401 cytosolic calcium ion transport 10/580 182/18722 0.0573820046053688 0.204039528608234 ATP2B1/DDIT3/DIAPH1/CALM1/GSTO1/CAV1/CALM2/VDAC1/YWHAE/CYBA 10 GO:1900407 regulation of cellular response to oxidative stress 6/580 89/18722 0.0580214303755798 0.205440798666067 P4HB/MET/PPIA/BMP7/TXN/GPX1 6 GO:0051251 positive regulation of lymphocyte activation 17/580 362/18722 0.0593228035397204 0.205440798666067 SLC39A10/CD46/SOX4/GLI3/PRKDC/DPP4/TFRC/CD81/CAV1/IL6ST/MIF/XBP1/CD55/PRKCZ/RHOA/HMGB1/IGF2 17 GO:0009141 nucleoside triphosphate metabolic process 7/580 112/18722 0.0594147452587152 0.205440798666067 ALDOA/ENO1/TMSB4X/DUT/TYMS/RHOA/RAN 7 GO:0010633 negative regulation of epithelial cell migration 7/580 112/18722 0.0594147452587152 0.205440798666067 SERPINF1/TACSTD2/NR2F2/MARVELD3/RHOA/HMGB1/CSNK2B 7 GO:0046686 response to cadmium ion 5/580 68/18722 0.0594642355904807 0.205440798666067 JUN/FOS/EGFR/PCNA/CDK1 5 GO:1901016 regulation of potassium ion transmembrane transporter activity 5/580 68/18722 0.0594642355904807 0.205440798666067 AKAP9/ITGB1/VAMP2/CAV1/YWHAE 5 GO:0032200 telomere organization 9/580 159/18722 0.0595420559870462 0.205440798666067 PPP1R10/HNRNPA1/PRKDC/ATRX/PTGES3/HNRNPC/HNRNPD/HNRNPA2B1/PCNA 9 GO:0002360 T cell lineage commitment 3/580 29/18722 0.0595747608866748 0.205440798666067 CTSL/PRKDC/RHOA 3 GO:0021591 ventricular system development 3/580 29/18722 0.0595747608866748 0.205440798666067 SEMA6D/CENPF/CDK6 3 GO:0022011 myelination in peripheral nervous system 3/580 29/18722 0.0595747608866748 0.205440798666067 ITGB4/DAG1/PLEC 3 GO:0030970 retrograde protein transport, ER to cytosol 3/580 29/18722 0.0595747608866748 0.205440798666067 HSP90B1/OS9/HM13 3 GO:0032292 peripheral nervous system axon ensheathment 3/580 29/18722 0.0595747608866748 0.205440798666067 ITGB4/DAG1/PLEC 3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity 3/580 29/18722 0.0595747608866748 0.205440798666067 EGFR/CCND3/CKS1B 3 GO:0048679 regulation of axon regeneration 3/580 29/18722 0.0595747608866748 0.205440798666067 LRP1/GRN/PTPRF 3 GO:0090025 regulation of monocyte chemotaxis 3/580 29/18722 0.0595747608866748 0.205440798666067 DUSP1/LGMN/HMGB1 3 GO:0095500 acetylcholine receptor signaling pathway 3/580 29/18722 0.0595747608866748 0.205440798666067 GNAQ/GNAI2/RGS10 3 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 3/580 29/18722 0.0595747608866748 0.205440798666067 P4HB/PPIA/GPX1 3 GO:1903513 endoplasmic reticulum to cytosol transport 3/580 29/18722 0.0595747608866748 0.205440798666067 HSP90B1/OS9/HM13 3 GO:0005513 detection of calcium ion 2/580 13/18722 0.0596312789075877 0.205440798666067 CALM1/CALM2 2 GO:0009437 carnitine metabolic process 2/580 13/18722 0.0596312789075877 0.205440798666067 POR/CROT 2 GO:0010745 negative regulation of macrophage derived foam cell differentiation 2/580 13/18722 0.0596312789075877 0.205440798666067 ITGAV/NFKBIA 2 GO:0010917 negative regulation of mitochondrial membrane potential 2/580 13/18722 0.0596312789075877 0.205440798666067 PMAIP1/ARL6IP5 2 GO:0021514 ventral spinal cord interneuron differentiation 2/580 13/18722 0.0596312789075877 0.205440798666067 GLI3/LMO4 2 GO:0021819 layer formation in cerebral cortex 2/580 13/18722 0.0596312789075877 0.205440798666067 ADGRG1/GLI3 2 GO:0032429 regulation of phospholipase A2 activity 2/580 13/18722 0.0596312789075877 0.205440798666067 LRP1/EGFR 2 GO:0034135 regulation of toll-like receptor 2 signaling pathway 2/580 13/18722 0.0596312789075877 0.205440798666067 HMGB1/CYBA 2 GO:0035331 negative regulation of hippo signaling 2/580 13/18722 0.0596312789075877 0.205440798666067 DLG5/VGLL4 2 GO:0035745 T-helper 2 cell cytokine production 2/580 13/18722 0.0596312789075877 0.205440798666067 CD81/PRKCZ 2 GO:0048012 hepatocyte growth factor receptor signaling pathway 2/580 13/18722 0.0596312789075877 0.205440798666067 MET/STMN1 2 GO:0051481 negative regulation of cytosolic calcium ion concentration 2/580 13/18722 0.0596312789075877 0.205440798666067 ATP2B1/LRP1 2 GO:0051956 negative regulation of amino acid transport 2/580 13/18722 0.0596312789075877 0.205440798666067 SLC43A2/ARL6IP5 2 GO:0060347 heart trabecula formation 2/580 13/18722 0.0596312789075877 0.205440798666067 TGFBR3/ADAMTS1 2 GO:0060707 trophoblast giant cell differentiation 2/580 13/18722 0.0596312789075877 0.205440798666067 HECTD1/NR2F2 2 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 2/580 13/18722 0.0596312789075877 0.205440798666067 EGR1/CITED2 2 GO:0070254 mucus secretion 2/580 13/18722 0.0596312789075877 0.205440798666067 EGFR/CYBA 2 GO:0070486 leukocyte aggregation 2/580 13/18722 0.0596312789075877 0.205440798666067 BMP7/S100A9 2 GO:0090161 Golgi ribbon formation 2/580 13/18722 0.0596312789075877 0.205440798666067 TRIP11/GCC2 2 GO:0098814 spontaneous synaptic transmission 2/580 13/18722 0.0596312789075877 0.205440798666067 APP/ITGB1 2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 2/580 13/18722 0.0596312789075877 0.205440798666067 PMAIP1/TIMP3 2 GO:1905244 regulation of modification of synaptic structure 2/580 13/18722 0.0596312789075877 0.205440798666067 RHOA/CDC42 2 GO:1905269 positive regulation of chromatin organization 2/580 13/18722 0.0596312789075877 0.205440798666067 TPR/MPHOSPH8 2 GO:2000551 regulation of T-helper 2 cell cytokine production 2/580 13/18722 0.0596312789075877 0.205440798666067 CD81/PRKCZ 2 GO:1903037 regulation of leukocyte cell-cell adhesion 16/580 336/18722 0.0596981445197018 0.205518926840217 CD46/SOX4/NFAT5/GLI3/DPP4/DLG5/TFRC/CD81/CAV1/IL6ST/XBP1/CD55/PRKCZ/RHOA/HMGB1/IGF2 16 GO:0032392 DNA geometric change 6/580 90/18722 0.0606201214263252 0.208230564810811 PURA/ATRX/HNRNPA2B1/HMGB1/HMGB3/HMGB2 6 GO:0046849 bone remodeling 6/580 90/18722 0.0606201214263252 0.208230564810811 EGFR/LGR4/LRP5/GJA1/ATP6AP1/TFRC 6 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 6/580 90/18722 0.0606201214263252 0.208230564810811 JUN/ADAMTS1/GJA1/GNAI2/RHOA/HPGD 6 GO:0045839 negative regulation of mitotic nuclear division 4/580 48/18722 0.0608201195285218 0.208445275463113 DUSP1/CENPF/BMP7/TPR 4 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 4/580 48/18722 0.0608201195285218 0.208445275463113 PDIA3/PMAIP1/CAV1/TIMP3 4 GO:0007051 spindle organization 10/580 184/18722 0.0608618972433686 0.208445275463113 DYNC1H1/HSPA1A/TACC2/ATRX/ASPM/TPR/RHOA/RAN/STMN1/RAB11A 10 GO:0055001 muscle cell development 10/580 184/18722 0.0608618972433686 0.208445275463113 KRT19/ITGB1/PLEC/ISL1/ADM/TBX3/ACTG1/KRT8/GPX1/CDK1 10 GO:0006631 fatty acid metabolic process 18/580 390/18722 0.0611042054295483 0.20875969506153 ACSS1/ILVBL/SLC27A2/HACD3/POR/PTGES2/CROT/CAV1/MIF/XBP1/ECHDC2/DEGS1/CYP2J2/ACADVL/PTGES3/GPX1/HADHA/HPGD 18 GO:0051656 establishment of organelle localization 18/580 390/18722 0.0611042054295483 0.20875969506153 ARMCX3/DYNC1H1/ITGB1/SYNE2/GJA1/ATP6AP1/TRIP11/TMED9/KIF5B/NPM1/CENPF/ARHGAP21/CFL1/PRKCZ/RAN/CDC42/DYNLT1/RAB11A 18 GO:0007272 ensheathment of neurons 8/580 136/18722 0.0611332411683087 0.20875969506153 ITGB4/DAG1/PLEC/NCSTN/GPC1/CTSC/JAM3/DEGS1 8 GO:0008366 axon ensheathment 8/580 136/18722 0.0611332411683087 0.20875969506153 ITGB4/DAG1/PLEC/NCSTN/GPC1/CTSC/JAM3/DEGS1 8 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 11/580 209/18722 0.0613280890808566 0.209271417692637 CTSD/DHCR24/POR/PMAIP1/SIAH2/S100A9/ARL6IP5/GPX1/RHOA/SERPINB9/HMGB1 11 GO:0016311 dephosphorylation 19/580 417/18722 0.0614343526854202 0.20948033309376 HSP90B1/SLC39A10/BOD1L1/DUSP1/PLPP3/DUSP6/PTPRF/PPP1R15A/ROCK1/CALM1/PPIA/PTPRA/CTDSPL/GNAI2/CALM2/PGP/YWHAE/CSNK2B/PHPT1 19 GO:0031623 receptor internalization 7/580 113/18722 0.0617347018232469 0.210350255076865 LRP1/ITGB1/LRPAP1/ADM/TFRC/CD81/CAV1 7 GO:0006260 DNA replication 13/580 260/18722 0.0620688465037687 0.211333971514662 JUN/EGFR/BOD1L1/RBBP6/PURA/ATRX/DUT/RRM2/PCNA/CDK1/GMNN/CDC42/CACYBP 13 GO:1901224 positive regulation of NIK/NF-kappaB signaling 5/580 69/18722 0.0625557997285541 0.212836155477326 EGFR/APP/NFAT5/RHOA/HMGB1 5 GO:0043433 negative regulation of DNA-binding transcription factor activity 10/580 185/18722 0.0626520998745743 0.213007979909828 UFL1/DDIT3/PURA/TCF7L2/EIF2AK4/BMP7/TMSB4X/ID1/NFKBIA/ANXA4 10 GO:0000086 G2/M transition of mitotic cell cycle 8/580 137/18722 0.0632575034114407 0.214070846056883 APP/PBX1/CALM1/CENPF/BRD4/CALM2/CDK1/RAB11A 8 GO:0010977 negative regulation of neuron projection development 8/580 137/18722 0.0632575034114407 0.214070846056883 LRP1/SEMA6A/SEMA6D/KANK1/RTN4/THOC2/MYLIP/RHOA 8 GO:0030879 mammary gland development 8/580 137/18722 0.0632575034114407 0.214070846056883 LRP5/GLI3/RTN4/TBX3/PRLR/CAV1/XBP1/GPX1 8 GO:0055123 digestive system development 8/580 137/18722 0.0632575034114407 0.214070846056883 EGFR/LGR4/WLS/GLI3/NIPBL/IL6ST/TYMS/IGF2 8 GO:0045582 positive regulation of T cell differentiation 6/580 91/18722 0.0632869089073778 0.214070846056883 CD46/SOX4/GLI3/XBP1/PRKCZ/RHOA 6 GO:0060191 regulation of lipase activity 6/580 91/18722 0.0632869089073778 0.214070846056883 LRP1/EGFR/GNAQ/POR/PRKCZ/RHOA 6 GO:1990874 vascular associated smooth muscle cell proliferation 6/580 91/18722 0.0632869089073778 0.214070846056883 JUN/ADAMTS1/GJA1/GNAI2/RHOA/HPGD 6 GO:0036294 cellular response to decreased oxygen levels 9/580 161/18722 0.0633991887126186 0.214294786847666 MALAT1/EGR1/P4HB/ENO1/ZFP36L1/SLC9A1/PMAIP1/CITED2/BMP7 9 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 7/580 114/18722 0.0641093086412535 0.215347313404577 TGFBR3/FERMT1/GPC3/CITED2/BMP7/CDKN1C/CSNK2B 7 GO:0071478 cellular response to radiation 10/580 186/18722 0.0644759845299726 0.215347313404577 RHOB/HSPA5/EGR1/DDB1/NPM1/NIPBL/EIF2AK4/ADIRF/PCNA/CYBA 10 GO:0006376 mRNA splice site selection 4/580 49/18722 0.0646776826050426 0.215347313404577 SF1/LUC7L3/SRSF6/SRSF5 4 GO:0006692 prostanoid metabolic process 4/580 49/18722 0.0646776826050426 0.215347313404577 PTGES2/MIF/PTGES3/HPGD 4 GO:0006693 prostaglandin metabolic process 4/580 49/18722 0.0646776826050426 0.215347313404577 PTGES2/MIF/PTGES3/HPGD 4 GO:0007622 rhythmic behavior 4/580 49/18722 0.0646776826050426 0.215347313404577 EGR1/NAGLU/ADRB1/ZFHX3 4 GO:0014075 response to amine 4/580 49/18722 0.0646776826050426 0.215347313404577 GLDC/CALM1/CDK1/RGS10 4 GO:0021515 cell differentiation in spinal cord 4/580 49/18722 0.0646776826050426 0.215347313404577 SOX4/ISL1/GLI3/LMO4 4 GO:0030857 negative regulation of epithelial cell differentiation 4/580 49/18722 0.0646776826050426 0.215347313404577 TBX3/CAV1/SRSF6/ID1 4 GO:0035088 establishment or maintenance of apical/basal cell polarity 4/580 49/18722 0.0646776826050426 0.215347313404577 FAT1/DLG5/RHOA/CDC42 4 GO:0061245 establishment or maintenance of bipolar cell polarity 4/580 49/18722 0.0646776826050426 0.215347313404577 FAT1/DLG5/RHOA/CDC42 4 GO:0086009 membrane repolarization 4/580 49/18722 0.0646776826050426 0.215347313404577 AKAP9/GJA5/CAV1/YWHAE 4 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 4/580 49/18722 0.0646776826050426 0.215347313404577 PMAIP1/TIMP3/GPX1/HMGB2 4 GO:1904752 regulation of vascular associated smooth muscle cell migration 4/580 49/18722 0.0646776826050426 0.215347313404577 LRP1/IQGAP1/ADAMTS1/RHOA 4 GO:0000132 establishment of mitotic spindle orientation 3/580 30/18722 0.0647292075122765 0.215347313404577 ITGB1/GJA1/DYNLT1 3 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 3/580 30/18722 0.0647292075122765 0.215347313404577 CALM1/GSTO1/CALM2 3 GO:0060218 hematopoietic stem cell differentiation 3/580 30/18722 0.0647292075122765 0.215347313404577 UFL1/N4BP2L2/PRKDC 3 GO:0060351 cartilage development involved in endochondral bone morphogenesis 3/580 30/18722 0.0647292075122765 0.215347313404577 SERPINH1/TRIP11/POR 3 GO:0060674 placenta blood vessel development 3/580 30/18722 0.0647292075122765 0.215347313404577 SPINT1/NR2F2/JUNB 3 GO:0061384 heart trabecula morphogenesis 3/580 30/18722 0.0647292075122765 0.215347313404577 TGFBR3/ADAMTS1/BMP7 3 GO:2000637 positive regulation of gene silencing by miRNA 3/580 30/18722 0.0647292075122765 0.215347313404577 EGFR/PUM1/EIF4G1 3 GO:2000648 positive regulation of stem cell proliferation 3/580 30/18722 0.0647292075122765 0.215347313404577 GJA1/N4BP2L2/TBX3 3 GO:0050867 positive regulation of cell activation 19/580 420/18722 0.0649590859878282 0.215957618963109 JUND/SLC39A10/CD46/SOX4/CTSC/GLI3/PRKDC/DPP4/TFRC/CD81/CAV1/IL6ST/MIF/XBP1/CD55/PRKCZ/RHOA/HMGB1/IGF2 19 GO:0031330 negative regulation of cellular catabolic process 13/580 262/18722 0.0651016828438239 0.216277090647589 RPL23/MET/CTSA/YBX1/ROCK1/EIF4G1/FUS/TIMP3/EIF3H/ATRAID/HNRNPC/HNRNPD/CIRBP 13 GO:0046651 lymphocyte proliferation 14/580 288/18722 0.065374309680616 0.216893895532974 SLC39A10/RPS6/CD46/NCSTN/PURA/DLG5/TFRC/CD81/IL6ST/MIF/CD55/CCND3/HMGB1/IGF2 14 GO:0032273 positive regulation of protein polymerization 8/580 138/18722 0.0654272490717615 0.216893895532974 AKAP9/IQGAP2/CLIP1/MET/HSPA1A/WASF2/PFN1/RHOA 8 GO:0055076 transition metal ion homeostasis 8/580 138/18722 0.0654272490717615 0.216893895532974 SLC39A10/APP/FTH1/ATP6AP1/TFRC/SLC40A1/SLC39A7/S100A9 8 GO:0033673 negative regulation of kinase activity 12/580 237/18722 0.0659874985296236 0.218553319286466 GADD45B/PLEC/DUSP1/LRP5/GNAQ/HMGCR/NPM1/NR2F2/PPIA/BMP7/CAV1/CDKN1C 12 GO:0032465 regulation of cytokinesis 6/580 92/18722 0.0660218046866231 0.218553319286466 CALM1/PKN2/CALM2/RHOA/CDC42/RAB11A 6 GO:0008064 regulation of actin polymerization or depolymerization 10/580 187/18722 0.0663336710168918 0.21942951913198 IQGAP2/KANK1/SPTAN1/SPTBN1/TMSB4X/WASF2/TRIOBP/PFN1/RASA1/RHOA 10 GO:0043523 regulation of neuron apoptotic process 11/580 212/18722 0.0664540807175147 0.219671591625558 JUN/LRP1/GRN/ISL1/ERBB3/DDIT3/LGMN/TFAP2A/RASA1/RHOA/CDC42 11 GO:0000054 ribosomal subunit export from nucleus 2/580 14/18722 0.0681794191950989 0.221589191601615 NPM1/RAN 2 GO:0000212 meiotic spindle organization 2/580 14/18722 0.0681794191950989 0.221589191601615 ATRX/ASPM 2 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis 2/580 14/18722 0.0681794191950989 0.221589191601615 SERPINH1/TRIP11 2 GO:0006999 nuclear pore organization 2/580 14/18722 0.0681794191950989 0.221589191601615 RTN4/TPR 2 GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process 2/580 14/18722 0.0681794191950989 0.221589191601615 DUT/TYMS 2 GO:0033750 ribosome localization 2/580 14/18722 0.0681794191950989 0.221589191601615 NPM1/RAN 2 GO:0036295 cellular response to increased oxygen levels 2/580 14/18722 0.0681794191950989 0.221589191601615 ATP6AP1/CAV1 2 GO:0038166 angiotensin-activated signaling pathway 2/580 14/18722 0.0681794191950989 0.221589191601615 ROCK1/CAV1 2 GO:0042921 glucocorticoid receptor signaling pathway 2/580 14/18722 0.0681794191950989 0.221589191601615 PTGES3/YWHAH 2 GO:0044764 multi-organism cellular process 2/580 14/18722 0.0681794191950989 0.221589191601615 CTSL/CAV1 2 GO:0045837 negative regulation of membrane potential 2/580 14/18722 0.0681794191950989 0.221589191601615 PMAIP1/ARL6IP5 2 GO:0046479 glycosphingolipid catabolic process 2/580 14/18722 0.0681794191950989 0.221589191601615 HEXA/NEU1 2 GO:0046655 folic acid metabolic process 2/580 14/18722 0.0681794191950989 0.221589191601615 FOLR1/SLC19A1 2 GO:0051645 Golgi localization 2/580 14/18722 0.0681794191950989 0.221589191601615 ARHGAP21/CDC42 2 GO:0060576 intestinal epithelial cell development 2/580 14/18722 0.0681794191950989 0.221589191601615 IL6ST/TYMS 2 GO:0060911 cardiac cell fate commitment 2/580 14/18722 0.0681794191950989 0.221589191601615 ISL1/TBX3 2 GO:0086103 G protein-coupled receptor signaling pathway involved in heart process 2/580 14/18722 0.0681794191950989 0.221589191601615 CAV1/GNAI2 2 GO:0099188 postsynaptic cytoskeleton organization 2/580 14/18722 0.0681794191950989 0.221589191601615 WASF2/ACTG1 2 GO:1901722 regulation of cell proliferation involved in kidney development 2/580 14/18722 0.0681794191950989 0.221589191601615 EGR1/BMP7 2 GO:1902036 regulation of hematopoietic stem cell differentiation 2/580 14/18722 0.0681794191950989 0.221589191601615 N4BP2L2/PRKDC 2 GO:1903894 regulation of IRE1-mediated unfolded protein response 2/580 14/18722 0.0681794191950989 0.221589191601615 HSPA5/UFL1 2 GO:1904294 positive regulation of ERAD pathway 2/580 14/18722 0.0681794191950989 0.221589191601615 TMEM259/CAV1 2 GO:1905049 negative regulation of metallopeptidase activity 2/580 14/18722 0.0681794191950989 0.221589191601615 LRP1/TIMP3 2 GO:2001171 positive regulation of ATP biosynthetic process 2/580 14/18722 0.0681794191950989 0.221589191601615 ENO1/TMSB4X 2 GO:0030832 regulation of actin filament length 10/580 188/18722 0.068225268194692 0.221589191601615 IQGAP2/KANK1/SPTAN1/SPTBN1/TMSB4X/WASF2/TRIOBP/PFN1/RASA1/RHOA 10 GO:0007632 visual behavior 4/580 50/18722 0.0686600724667053 0.222380220781787 APP/ITGB1/HMGCR/DYNLRB1 4 GO:0050873 brown fat cell differentiation 4/580 50/18722 0.0686600724667053 0.222380220781787 ADRB1/ARL4A/BMP7/PLAC8 4 GO:0060425 lung morphogenesis 4/580 50/18722 0.0686600724667053 0.222380220781787 DAG1/DLG5/SRSF6/CDC42 4 GO:1904738 vascular associated smooth muscle cell migration 4/580 50/18722 0.0686600724667053 0.222380220781787 LRP1/IQGAP1/ADAMTS1/RHOA 4 GO:0032088 negative regulation of NF-kappaB transcription factor activity 6/580 93/18722 0.0688247720877898 0.222758535128956 UFL1/DDIT3/BMP7/TMSB4X/NFKBIA/ANXA4 6 GO:0003208 cardiac ventricle morphogenesis 5/580 71/18722 0.0690058685074303 0.222934042449179 LRP2/TGFBR3/SOX4/ISL1/DSP 5 GO:0033559 unsaturated fatty acid metabolic process 7/580 116/18722 0.0690227953401028 0.222934042449179 PTGES2/MIF/DEGS1/CYP2J2/PTGES3/GPX1/HPGD 7 GO:0043200 response to amino acid 7/580 116/18722 0.0690227953401028 0.222934042449179 UFL1/SLC38A9/XBP1/HNRNPD/RHOA/PCNA/CYBA 7 GO:0050792 regulation of viral process 9/580 164/18722 0.0694760909766877 0.224019497288214 P4HB/DDB1/HACD3/PKN2/PPIA/RSF1/STOM/MPHOSPH8/DYNLT1 9 GO:0032943 mononuclear cell proliferation 14/580 291/18722 0.0698810999074159 0.224019497288214 SLC39A10/RPS6/CD46/NCSTN/PURA/DLG5/TFRC/CD81/IL6ST/MIF/CD55/CCND3/HMGB1/IGF2 14 GO:0001516 prostaglandin biosynthetic process 3/580 31/18722 0.0700813520865087 0.224019497288214 PTGES2/MIF/PTGES3 3 GO:0006613 cotranslational protein targeting to membrane 3/580 31/18722 0.0700813520865087 0.224019497288214 SIL1/SEC62/SSR2 3 GO:0032148 activation of protein kinase B activity 3/580 31/18722 0.0700813520865087 0.224019497288214 PPIA/TXN/PRKCZ 3 GO:0035115 embryonic forelimb morphogenesis 3/580 31/18722 0.0700813520865087 0.224019497288214 TBX3/NIPBL/TFAP2A 3 GO:0046457 prostanoid biosynthetic process 3/580 31/18722 0.0700813520865087 0.224019497288214 PTGES2/MIF/PTGES3 3 GO:0055022 negative regulation of cardiac muscle tissue growth 3/580 31/18722 0.0700813520865087 0.224019497288214 GJA1/CITED2/VGLL4 3 GO:0060055 angiogenesis involved in wound healing 3/580 31/18722 0.0700813520865087 0.224019497288214 DAG1/XBP1/GPX1 3 GO:0060148 positive regulation of posttranscriptional gene silencing 3/580 31/18722 0.0700813520865087 0.224019497288214 EGFR/PUM1/EIF4G1 3 GO:0061117 negative regulation of heart growth 3/580 31/18722 0.0700813520865087 0.224019497288214 GJA1/CITED2/VGLL4 3 GO:0071480 cellular response to gamma radiation 3/580 31/18722 0.0700813520865087 0.224019497288214 HSPA5/EGR1/CYBA 3 GO:0090183 regulation of kidney development 3/580 31/18722 0.0700813520865087 0.224019497288214 LGR4/TACSTD2/MAGED1 3 GO:1905144 response to acetylcholine 3/580 31/18722 0.0700813520865087 0.224019497288214 GNAQ/GNAI2/RGS10 3 GO:1905145 cellular response to acetylcholine 3/580 31/18722 0.0700813520865087 0.224019497288214 GNAQ/GNAI2/RGS10 3 GO:0032886 regulation of microtubule-based process 12/580 240/18722 0.071035568795634 0.22675801679375 AKAP9/MACF1/DYNC1H1/CLIP1/MET/HSPA1A/DIAPH1/ROCK1/NPM1/TPR/RHOA/STMN1 12 GO:0070085 glycosylation 12/580 240/18722 0.071035568795634 0.22675801679375 RPN2/EXTL2/B3GAT3/DDOST/TRIP11/C1GALT1/GALNT11/MAN1A2/MGAT1/MPDU1/TMEM59/TUSC3 12 GO:0010389 regulation of G2/M transition of mitotic cell cycle 6/580 94/18722 0.0716957263476497 0.228551626622974 APP/PBX1/CENPF/BRD4/CDK1/RAB11A 6 GO:0019080 viral gene expression 6/580 94/18722 0.0716957263476497 0.228551626622974 JUN/EIF3A/RSF1/EIF2AK4/MGAT1/CANX 6 GO:0099111 microtubule-based transport 10/580 190/18722 0.0721105748627092 0.229716632661959 ARMCX3/DYNC1H1/APP/DST/PURA/KIF5B/ARHGAP21/HSPA8/PRKCZ/CDC42 10 GO:0001707 mesoderm formation 5/580 72/18722 0.0723636659894075 0.229893039970447 ITGB4/ITGB1/WLS/GJA1/BMP7 5 GO:0030330 DNA damage response, signal transduction by p53 class mediator 5/580 72/18722 0.0723636659894075 0.229893039970447 SOX4/ATRX/PMAIP1/NPM1/MIF 5 GO:0055021 regulation of cardiac muscle tissue growth 5/580 72/18722 0.0723636659894075 0.229893039970447 TGFBR3/GJA1/CITED2/VGLL4/CDK1 5 GO:0071479 cellular response to ionizing radiation 5/580 72/18722 0.0723636659894075 0.229893039970447 RHOB/HSPA5/EGR1/NIPBL/CYBA 5 GO:0006636 unsaturated fatty acid biosynthetic process 4/580 51/18722 0.0727659658590556 0.230090955956903 PTGES2/MIF/DEGS1/PTGES3 4 GO:0009948 anterior/posterior axis specification 4/580 51/18722 0.0727659658590556 0.230090955956903 WLS/DDIT3/TBX3/GPC3 4 GO:0021872 forebrain generation of neurons 4/580 51/18722 0.0727659658590556 0.230090955956903 NRP2/GLI3/ASPM/RHOA 4 GO:0045104 intermediate filament cytoskeleton organization 4/580 51/18722 0.0727659658590556 0.230090955956903 MACF1/PLEC/DST/DSP 4 GO:0045661 regulation of myoblast differentiation 4/580 51/18722 0.0727659658590556 0.230090955956903 ZFP36L1/BTG1/DDIT3/TBX3 4 GO:0044843 cell cycle G1/S phase transition 12/580 241/18722 0.0727722632149224 0.230090955956903 EGFR/RPS6/ITGB1/SOX4/ADAMTS1/PRKDC/BRD4/CDK6/EIF4G1/CTDSPL/E2F4/CCND3 12 GO:0071824 protein-DNA complex subunit organization 12/580 241/18722 0.0727722632149224 0.230090955956903 RPL23/BPTF/ATRX/BDP1/NPM1/CENPF/RSF1/HMGB1/CENPN/HMGB2/GMNN/DNAJC9 12 GO:0045446 endothelial cell differentiation 7/580 118/18722 0.0741555427919549 0.234305318971048 MET/BTG1/ROCK1/NR2F2/FSTL1/ID1/GPX1 7 GO:0008593 regulation of Notch signaling pathway 6/580 95/18722 0.0746345351310362 0.235339134165728 AAK1/CD46/GALNT11/BMP7/IL6ST/NFKBIA 6 GO:0036473 cell death in response to oxidative stress 6/580 95/18722 0.0746345351310362 0.235339134165728 P4HB/MET/PPIA/TXN/ARL6IP5/GPX1 6 GO:1901379 regulation of potassium ion transmembrane transport 6/580 95/18722 0.0746345351310362 0.235339134165728 AKAP9/KCNN4/ITGB1/VAMP2/CAV1/YWHAE 6 GO:0007596 blood coagulation 11/580 217/18722 0.075598018889267 0.237499317660424 F5/FBLN1/LMAN1/ANXA5/GNAQ/PPIA/CAV1/IL6ST/ACTG1/TFPI2/MYL12A 11 GO:0009954 proximal/distal pattern formation 3/580 32/18722 0.075625992142569 0.237499317660424 PBX1/GLI3/IRX2 3 GO:0014044 Schwann cell development 3/580 32/18722 0.075625992142569 0.237499317660424 ITGB4/DAG1/PLEC 3 GO:0060317 cardiac epithelial to mesenchymal transition 3/580 32/18722 0.075625992142569 0.237499317660424 TGFBR3/RTN4/TBX3 3 GO:0060914 heart formation 3/580 32/18722 0.075625992142569 0.237499317660424 LRP2/ISL1/FOLR1 3 GO:1900745 positive regulation of p38MAPK cascade 3/580 32/18722 0.075625992142569 0.237499317660424 GADD45B/EMC10/GADD45G 3 GO:0045739 positive regulation of DNA repair 5/580 73/18722 0.0758093667014756 0.237914550963943 EGFR/PRKDC/FUS/HMGB1/PCNA 5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 9/580 167/18722 0.0759047585165846 0.23805329188175 TENM3/CDH1/ITGB1/BSG/CADM1/DSG2/FAT1/DSC3/DSC2 9 GO:0018108 peptidyl-tyrosine phosphorylation 17/580 375/18722 0.0765018266529924 0.238111097910685 EGFR/EFEMP1/APP/MET/IQGAP1/ISL1/EPHB4/ERBB3/IGF1R/CSH1/CD81/PRLR/CAV1/IL6ST/MIF/PRKCZ/IGF2 17 GO:0038061 NIK/NF-kappaB signaling 8/580 143/18722 0.0769611972161446 0.238111097910685 EGFR/APP/NFAT5/BMP7/TMSB4X/NFKBIA/RHOA/HMGB1 8 GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 4/580 52/18722 0.0769938941833549 0.238111097910685 PLPP3/COPA/LMAN2/ARF5 4 GO:0045103 intermediate filament-based process 4/580 52/18722 0.0769938941833549 0.238111097910685 MACF1/PLEC/DST/DSP 4 GO:0060071 Wnt signaling pathway, planar cell polarity pathway 4/580 52/18722 0.0769938941833549 0.238111097910685 ZNRF3/GPC3/RHOA/CDC42 4 GO:0010452 histone H3-K36 methylation 2/580 15/18722 0.0771006909166827 0.238111097910685 BRD4/NSD1 2 GO:0031958 corticosteroid receptor signaling pathway 2/580 15/18722 0.0771006909166827 0.238111097910685 PTGES3/YWHAH 2 GO:0032328 alanine transport 2/580 15/18722 0.0771006909166827 0.238111097910685 SLC3A2/SLC38A2 2 GO:0032354 response to follicle-stimulating hormone 2/580 15/18722 0.0771006909166827 0.238111097910685 TGFBR3/POR 2 GO:0033599 regulation of mammary gland epithelial cell proliferation 2/580 15/18722 0.0771006909166827 0.238111097910685 RTN4/GPX1 2 GO:0042074 cell migration involved in gastrulation 2/580 15/18722 0.0771006909166827 0.238111097910685 LRP5/GPC3 2 GO:0042159 lipoprotein catabolic process 2/580 15/18722 0.0771006909166827 0.238111097910685 CTSD/NOTUM 2 GO:0042994 cytoplasmic sequestering of transcription factor 2/580 15/18722 0.0771006909166827 0.238111097910685 TMSB4X/NFKBIA 2 GO:0045176 apical protein localization 2/580 15/18722 0.0771006909166827 0.238111097910685 DLG5/JAM3 2 GO:0051938 L-glutamate import 2/580 15/18722 0.0771006909166827 0.238111097910685 ITGB1/ARL6IP5 2 GO:0060413 atrial septum morphogenesis 2/580 15/18722 0.0771006909166827 0.238111097910685 SOX4/ISL1 2 GO:0070207 protein homotrimerization 2/580 15/18722 0.0771006909166827 0.238111097910685 SLC1A5/MIF 2 GO:0070831 basement membrane assembly 2/580 15/18722 0.0771006909166827 0.238111097910685 LAMB1/DAG1 2 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus 2/580 15/18722 0.0771006909166827 0.238111097910685 NPM1/RAN 2 GO:0072224 metanephric glomerulus development 2/580 15/18722 0.0771006909166827 0.238111097910685 EGR1/LGR4 2 GO:0098712 L-glutamate import across plasma membrane 2/580 15/18722 0.0771006909166827 0.238111097910685 ITGB1/ARL6IP5 2 GO:1904424 regulation of GTP binding 2/580 15/18722 0.0771006909166827 0.238111097910685 MET/STMN1 2 GO:1905146 lysosomal protein catabolic process 2/580 15/18722 0.0771006909166827 0.238111097910685 LRP2/LRP1 2 GO:0001935 endothelial cell proliferation 10/580 193/18722 0.0781949490493836 0.241330264119896 NRP2/GJA1/NR2F2/EMC10/CAV1/MYDGF/HMGB1/IGF2/HMGB2/CYBA 10 GO:0006635 fatty acid beta-oxidation 5/580 74/18722 0.0793424188765579 0.24392408647509 SLC27A2/CROT/ECHDC2/ACADVL/HADHA 5 GO:0006801 superoxide metabolic process 5/580 74/18722 0.0793424188765579 0.24392408647509 EGFR/SOD3/BMP7/GNAI2/CYBA 5 GO:0007040 lysosome organization 5/580 74/18722 0.0793424188765579 0.24392408647509 GRN/GAA/NAGLU/ATP6AP2/HOOK2 5 GO:0080171 lytic vacuole organization 5/580 74/18722 0.0793424188765579 0.24392408647509 GRN/GAA/NAGLU/ATP6AP2/HOOK2 5 GO:1903201 regulation of oxidative stress-induced cell death 5/580 74/18722 0.0793424188765579 0.24392408647509 P4HB/MET/PPIA/TXN/GPX1 5 GO:0034764 positive regulation of transmembrane transport 11/580 219/18722 0.0794676959941359 0.24392408647509 AKAP9/TCAF1/KCNN4/ITGB1/SLC9A1/CALM1/KIF5B/GPC3/GSTO1/TMSB4X/CALM2 11 GO:2001020 regulation of response to DNA damage stimulus 11/580 219/18722 0.0794676959941359 0.24392408647509 TPT1/EGFR/PPP1R10/PRKDC/PMAIP1/NPM1/IER3/FUS/MIF/HMGB1/PCNA 11 GO:0002761 regulation of myeloid leukocyte differentiation 7/580 120/18722 0.0795073995046735 0.24392408647509 FBN1/JUN/FOS/ZFP36L1/ESRRA/ATP6AP1/CDK6 7 GO:0071901 negative regulation of protein serine/threonine kinase activity 7/580 120/18722 0.0795073995046735 0.24392408647509 DUSP1/LRP5/HMGCR/NR2F2/BMP7/CAV1/CDKN1C 7 GO:0008544 epidermis development 15/580 324/18722 0.0803188864213536 0.246251246371599 LAMA5/SVEP1/EGFR/LGR5/LGR4/PLEC/ZFP36L1/YBX1/FERMT1/ROCK1/TRIOBP/DSP/NCOA3/SRSF6/TXNIP 15 GO:0031214 biomineral tissue development 9/580 169/18722 0.080386753259552 0.246296962720801 FBN2/ATP2B1/LGR4/ROCK1/GPC3/NOTUM/BMP7/TFAP2A/ATRAID 9 GO:0031279 regulation of cyclase activity 4/580 53/18722 0.0813422507361497 0.246671844029789 AKAP9/CALM1/GNAI2/CALM2 4 GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 4/580 53/18722 0.0813422507361497 0.246671844029789 MET/ADM/GNAI2/STMN1 4 GO:0071320 cellular response to cAMP 4/580 53/18722 0.0813422507361497 0.246671844029789 AKAP9/HSPA5/APP/ZFP36L1 4 GO:1903202 negative regulation of oxidative stress-induced cell death 4/580 53/18722 0.0813422507361497 0.246671844029789 MET/PPIA/TXN/GPX1 4 GO:1990090 cellular response to nerve growth factor stimulus 4/580 53/18722 0.0813422507361497 0.246671844029789 HSPA5/APP/BPTF/ID1 4 GO:2000772 regulation of cellular senescence 4/580 53/18722 0.0813422507361497 0.246671844029789 YBX1/PRKDC/YPEL3/CDK6 4 GO:0003382 epithelial cell morphogenesis 3/580 33/18722 0.0813576883985587 0.246671844029789 MET/SPINT2/FAT1 3 GO:0010984 regulation of lipoprotein particle clearance 3/580 33/18722 0.0813576883985587 0.246671844029789 LRPAP1/CNPY2/MYLIP 3 GO:0042558 pteridine-containing compound metabolic process 3/580 33/18722 0.0813576883985587 0.246671844029789 FOLR1/SLC19A1/TYMS 3 GO:0045648 positive regulation of erythrocyte differentiation 3/580 33/18722 0.0813576883985587 0.246671844029789 HSPA1A/PRKDC/HMGB2 3 GO:0048333 mesodermal cell differentiation 3/580 33/18722 0.0813576883985587 0.246671844029789 ITGB4/ITGB1/GJA1 3 GO:0070570 regulation of neuron projection regeneration 3/580 33/18722 0.0813576883985587 0.246671844029789 LRP1/GRN/PTPRF 3 GO:1900181 negative regulation of protein localization to nucleus 3/580 33/18722 0.0813576883985587 0.246671844029789 FERMT1/MAGED1/TRIM29 3 GO:1901976 regulation of cell cycle checkpoint 3/580 33/18722 0.0813576883985587 0.246671844029789 DUSP1/PPP1R10/TPR 3 GO:1904031 positive regulation of cyclin-dependent protein kinase activity 3/580 33/18722 0.0813576883985587 0.246671844029789 EGFR/CCND3/CKS1B 3 GO:2000036 regulation of stem cell population maintenance 3/580 33/18722 0.0813576883985587 0.246671844029789 ZC3H13/BMP7/NCOA3 3 GO:0097529 myeloid leukocyte migration 11/580 220/18722 0.0814482131799428 0.246785432898967 CSF3R/DUSP1/BSG/DPP4/JAM3/CD81/PPIA/MIF/LGMN/S100A9/HMGB1 11 GO:0002224 toll-like receptor signaling pathway 7/580 121/18722 0.0822653140304457 0.249098942419012 LGR4/RTN4/CAV1/NINJ1/NFKBIA/HMGB1/CYBA 7 GO:0042254 ribosome biogenesis 14/580 299/18722 0.0828843125140365 0.250394009893768 RPS21/RPLP0/RPL23A/RPS6/RPL6/RPL7/RPS16/RPL14/RPS25/RPS17/PRKDC/NPM1/RAN/FBL 14 GO:0036465 synaptic vesicle recycling 5/580 75/18722 0.082962195064781 0.250394009893768 ROCK1/CALM1/VAMP2/ACTG1/CANX 5 GO:0045913 positive regulation of carbohydrate metabolic process 5/580 75/18722 0.082962195064781 0.250394009893768 APP/DDB1/PMAIP1/HMGB1/IGF2 5 GO:1902369 negative regulation of RNA catabolic process 5/580 75/18722 0.082962195064781 0.250394009893768 YBX1/FUS/HNRNPC/HNRNPD/CIRBP 5 GO:2001259 positive regulation of cation channel activity 5/580 75/18722 0.082962195064781 0.250394009893768 CALM1/KIF5B/GSTO1/TMSB4X/CALM2 5 GO:1902882 regulation of response to oxidative stress 6/580 98/18722 0.08385606403046 0.252927726203417 P4HB/MET/PPIA/BMP7/TXN/GPX1 6 GO:0110148 biomineralization 9/580 171/18722 0.0850259240889104 0.254387791618262 FBN2/ATP2B1/LGR4/ROCK1/GPC3/NOTUM/BMP7/TFAP2A/ATRAID 9 GO:0051208 sequestering of calcium ion 7/580 122/18722 0.085077730217301 0.254387791618262 HSP90B1/DDIT3/DIAPH1/CALM1/GSTO1/CALM2/CYBA 7 GO:0023061 signal release 20/580 463/18722 0.0853961968788216 0.254387791618262 LRP1/EGFR/WLS/SOX4/ISL1/LRP5/GJA1/ADM/DPP4/HMGCR/CALM1/TBX3/KIF5B/TCF7L2/SLC6A4/HMGN3/VAMP2/DYNLL1/FAM3B/PHPT1 20 GO:0007599 hemostasis 11/580 222/18722 0.0855007807504193 0.254387791618262 F5/FBLN1/LMAN1/ANXA5/GNAQ/PPIA/CAV1/IL6ST/ACTG1/TFPI2/MYL12A 11 GO:0050817 coagulation 11/580 222/18722 0.0855007807504193 0.254387791618262 F5/FBLN1/LMAN1/ANXA5/GNAQ/PPIA/CAV1/IL6ST/ACTG1/TFPI2/MYL12A 11 GO:0010524 positive regulation of calcium ion transport into cytosol 4/580 54/18722 0.0858092979275524 0.254387791618262 CALM1/GSTO1/CAV1/CALM2 4 GO:0032330 regulation of chondrocyte differentiation 4/580 54/18722 0.0858092979275524 0.254387791618262 GLG1/EFEMP1/GLI3/POR 4 GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin 2/580 16/18722 0.0863638621727017 0.254387791618262 ENPEP/ATP6AP2 2 GO:0002713 negative regulation of B cell mediated immunity 2/580 16/18722 0.0863638621727017 0.254387791618262 CD46/CD55 2 GO:0002830 positive regulation of type 2 immune response 2/580 16/18722 0.0863638621727017 0.254387791618262 CD81/PRKCZ 2 GO:0002890 negative regulation of immunoglobulin mediated immune response 2/580 16/18722 0.0863638621727017 0.254387791618262 CD46/CD55 2 GO:0002921 negative regulation of humoral immune response 2/580 16/18722 0.0863638621727017 0.254387791618262 CD46/CD55 2 GO:0009415 response to water 2/580 16/18722 0.0863638621727017 0.254387791618262 PLEC/KRT8 2 GO:0019081 viral translation 2/580 16/18722 0.0863638621727017 0.254387791618262 EIF3A/EIF2AK4 2 GO:0021783 preganglionic parasympathetic fiber development 2/580 16/18722 0.0863638621727017 0.254387791618262 NRP2/TFAP2A 2 GO:0030540 female genitalia development 2/580 16/18722 0.0863638621727017 0.254387791618262 LRP2/TBX3 2 GO:0030575 nuclear body organization 2/580 16/18722 0.0863638621727017 0.254387791618262 SF1/SERBP1 2 GO:0032274 gonadotropin secretion 2/580 16/18722 0.0863638621727017 0.254387791618262 GJA1/TBX3 2 GO:0035751 regulation of lysosomal lumen pH 2/580 16/18722 0.0863638621727017 0.254387791618262 GRN/ATP6AP2 2 GO:0044849 estrous cycle 2/580 16/18722 0.0863638621727017 0.254387791618262 EGR1/PCNA 2 GO:0048557 embryonic digestive tract morphogenesis 2/580 16/18722 0.0863638621727017 0.254387791618262 GLI3/NIPBL 2 GO:0050862 positive regulation of T cell receptor signaling pathway 2/580 16/18722 0.0863638621727017 0.254387791618262 KCNN4/CD81 2 GO:0050884 neuromuscular process controlling posture 2/580 16/18722 0.0863638621727017 0.254387791618262 GAA/TMEM150C 2 GO:0051238 sequestering of metal ion 2/580 16/18722 0.0863638621727017 0.254387791618262 FTH1/S100A9 2 GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 2/580 16/18722 0.0863638621727017 0.254387791618262 HSPA1A/NFKBIA 2 GO:0072109 glomerular mesangium development 2/580 16/18722 0.0863638621727017 0.254387791618262 EGR1/BMP7 2 GO:0090231 regulation of spindle checkpoint 2/580 16/18722 0.0863638621727017 0.254387791618262 DUSP1/TPR 2 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint 2/580 16/18722 0.0863638621727017 0.254387791618262 DUSP1/TPR 2 GO:0097202 activation of cysteine-type endopeptidase activity 2/580 16/18722 0.0863638621727017 0.254387791618262 ASPH/LGMN 2 GO:0098969 neurotransmitter receptor transport to postsynaptic membrane 2/580 16/18722 0.0863638621727017 0.254387791618262 VAMP2/RAB11A 2 GO:0099633 protein localization to postsynaptic specialization membrane 2/580 16/18722 0.0863638621727017 0.254387791618262 DAG1/PRKCZ 2 GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane 2/580 16/18722 0.0863638621727017 0.254387791618262 DAG1/PRKCZ 2 GO:1902570 protein localization to nucleolus 2/580 16/18722 0.0863638621727017 0.254387791618262 NPM1/RAN 2 GO:1903504 regulation of mitotic spindle checkpoint 2/580 16/18722 0.0863638621727017 0.254387791618262 DUSP1/TPR 2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway 2/580 16/18722 0.0863638621727017 0.254387791618262 ZNRF3/GPC3 2 GO:2000651 positive regulation of sodium ion transmembrane transporter activity 2/580 16/18722 0.0863638621727017 0.254387791618262 SLC9A1/KIF5B 2 GO:2001224 positive regulation of neuron migration 2/580 16/18722 0.0863638621727017 0.254387791618262 SEMA6A/NIPBL 2 GO:0014855 striated muscle cell proliferation 5/580 76/18722 0.0866679942421724 0.255122051405281 TGFBR3/GJA1/CITED2/VGLL4/CDK1 5 GO:0060291 long-term synaptic potentiation 6/580 99/18722 0.0870640371582922 0.255924634766331 APP/NCSTN/EIF2AK4/VAMP2/LGMN/PRKCZ 6 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 3/580 34/18722 0.0872707956868204 0.255924634766331 CALM1/GSTO1/CALM2 3 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 3/580 34/18722 0.0872707956868204 0.255924634766331 PMAIP1/NPM1/MIF 3 GO:0048536 spleen development 3/580 34/18722 0.0872707956868204 0.255924634766331 PBX1/PRKDC/CITED2 3 GO:0098751 bone cell development 3/580 34/18722 0.0872707956868204 0.255924634766331 FBN1/ATP6AP1/WASF2 3 GO:1990000 amyloid fibril formation 3/580 34/18722 0.0872707956868204 0.255924634766331 APP/SIAH1/SIAH2 3 GO:0002221 pattern recognition receptor signaling pathway 9/580 172/18722 0.0874044296159504 0.255993704120772 LGR4/HSPA1A/RTN4/PUM1/CAV1/NINJ1/NFKBIA/HMGB1/CYBA 9 GO:0042770 signal transduction in response to DNA damage 9/580 172/18722 0.0874044296159504 0.255993704120772 SOX4/PPP1R10/PRKDC/ATRX/PMAIP1/NPM1/EIF2AK4/MIF/CDK1 9 GO:0006690 icosanoid metabolic process 7/580 123/18722 0.087944494235309 0.257413368589315 MGST3/PTGES2/MIF/CYP2J2/PTGES3/GPX1/HPGD 7 GO:0050863 regulation of T cell activation 15/580 329/18722 0.0886167170515021 0.259217830821721 CD46/SOX4/GLI3/DPP4/DLG5/TFRC/CD81/CAV1/IL6ST/XBP1/CD55/PRKCZ/RHOA/HMGB1/IGF2 15 GO:2001056 positive regulation of cysteine-type endopeptidase activity 8/580 148/18722 0.0896392185848793 0.262044001029713 CTSD/PMAIP1/ASPH/LGMN/S100A9/ARL6IP5/RHOA/HMGB1 8 GO:0009062 fatty acid catabolic process 6/580 100/18722 0.090338511293707 0.263750724218112 ILVBL/SLC27A2/CROT/ECHDC2/ACADVL/HADHA 6 GO:0006414 translational elongation 4/580 55/18722 0.0903931744578952 0.263750724218112 EEF1A1/EEF1B2/TUFM/NEMF 4 GO:0010676 positive regulation of cellular carbohydrate metabolic process 4/580 55/18722 0.0903931744578952 0.263750724218112 DDB1/PMAIP1/HMGB1/IGF2 4 GO:0048644 muscle organ morphogenesis 5/580 77/18722 0.0904590439810443 0.263777437966042 LRP2/TGFBR3/ISL1/ARID5B/DSP 5 GO:0009132 nucleoside diphosphate metabolic process 7/580 124/18722 0.0908654230083378 0.26479641755124 GAPDH/LDHA/APP/ALDOA/ENO1/TPI1/PKM 7 GO:0045619 regulation of lymphocyte differentiation 9/580 174/18722 0.0922791075749738 0.26850630584944 CD46/SOX4/ZFP36L1/GLI3/PRKDC/XBP1/PRKCZ/RHOA/HMGB1 9 GO:0048639 positive regulation of developmental growth 9/580 174/18722 0.0922791075749738 0.26850630584944 LRP1/GOLGA4/MACF1/TGFBR3/PRKDC/NIPBL/IGF2/CDK1/RAB11A 9 GO:0009411 response to UV 8/580 149/18722 0.0923116712649441 0.26850630584944 EGFR/TP53I13/DDB1/NPM1/EIF2AK4/GPX1/CIRBP/PCNA 8 GO:0010664 negative regulation of striated muscle cell apoptotic process 3/580 35/18722 0.0933594918543511 0.270034201874743 PPP1R10/HMGCR/BMP7 3 GO:0010765 positive regulation of sodium ion transport 3/580 35/18722 0.0933594918543511 0.270034201874743 SLC9A1/KIF5B/PRSS8 3 GO:0031076 embryonic camera-type eye development 3/580 35/18722 0.0933594918543511 0.270034201874743 CITED2/BMP7/TFAP2A 3 GO:0040001 establishment of mitotic spindle localization 3/580 35/18722 0.0933594918543511 0.270034201874743 ITGB1/GJA1/DYNLT1 3 GO:0045454 cell redox homeostasis 3/580 35/18722 0.0933594918543511 0.270034201874743 DDIT3/TXN/GPX1 3 GO:0045880 positive regulation of smoothened signaling pathway 3/580 35/18722 0.0933594918543511 0.270034201874743 DLG5/POR/GPC3 3 GO:0050654 chondroitin sulfate proteoglycan metabolic process 3/580 35/18722 0.0933594918543511 0.270034201874743 CHPF/CHST12/B3GAT3 3 GO:0060236 regulation of mitotic spindle organization 3/580 35/18722 0.0933594918543511 0.270034201874743 DYNC1H1/HSPA1A/TPR 3 GO:1903514 release of sequestered calcium ion into cytosol by endoplasmic reticulum 3/580 35/18722 0.0933594918543511 0.270034201874743 CALM1/GSTO1/CALM2 3 GO:0071902 positive regulation of protein serine/threonine kinase activity 10/580 200/18722 0.0935938729980618 0.270543880244863 EGFR/IQGAP1/ERP29/CALM1/MAGED1/CCND3/CALM2/RHOA/CKS1B/IGF2 10 GO:0055007 cardiac muscle cell differentiation 7/580 125/18722 0.0938403045340517 0.271087736886879 ITGB1/PLEC/ISL1/SLC9A1/TBX3/CDK1/CACYBP 7 GO:0051495 positive regulation of cytoskeleton organization 11/580 226/18722 0.0939724773515955 0.271089644563134 AKAP9/DYNC1H1/IQGAP2/CLIP1/MET/HSPA1A/WASF2/ID1/PFN1/RHOA/CDC42 11 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 5/580 78/18722 0.094334502674784 0.271089644563134 DHCR24/POR/SIAH2/GPX1/SERPINB9 5 GO:0090559 regulation of membrane permeability 5/580 78/18722 0.094334502674784 0.271089644563134 HSPA1A/SLC9A1/PMAIP1/JAM3/DYNLT1 5 GO:0031529 ruffle organization 4/580 56/18722 0.095091902434326 0.271089644563134 KANK1/TACSTD2/CAV1/PFN1 4 GO:0046456 icosanoid biosynthetic process 4/580 56/18722 0.095091902434326 0.271089644563134 MGST3/PTGES2/MIF/PTGES3 4 GO:0051784 negative regulation of nuclear division 4/580 56/18722 0.095091902434326 0.271089644563134 DUSP1/CENPF/BMP7/TPR 4 GO:0090175 regulation of establishment of planar polarity 4/580 56/18722 0.095091902434326 0.271089644563134 ZNRF3/GPC3/RHOA/CDC42 4 GO:1990089 response to nerve growth factor 4/580 56/18722 0.095091902434326 0.271089644563134 HSPA5/APP/BPTF/ID1 4 GO:0065004 protein-DNA complex assembly 10/580 201/18722 0.0959311270711147 0.271089644563134 ATRX/BDP1/NPM1/CENPF/RSF1/HMGB1/CENPN/HMGB2/GMNN/DNAJC9 10 GO:0001780 neutrophil homeostasis 2/580 17/18722 0.0959392721889741 0.271089644563134 JAM3/HMGB1 2 GO:0001829 trophectodermal cell differentiation 2/580 17/18722 0.0959392721889741 0.271089644563134 CITED2/JUNB 2 GO:0006577 amino-acid betaine metabolic process 2/580 17/18722 0.0959392721889741 0.271089644563134 POR/CROT 2 GO:0009200 deoxyribonucleoside triphosphate metabolic process 2/580 17/18722 0.0959392721889741 0.271089644563134 DUT/TYMS 2 GO:0010566 regulation of ketone biosynthetic process 2/580 17/18722 0.0959392721889741 0.271089644563134 EGR1/ADM 2 GO:0010715 regulation of extracellular matrix disassembly 2/580 17/18722 0.0959392721889741 0.271089644563134 LRP1/DPP4 2 GO:0031445 regulation of heterochromatin assembly 2/580 17/18722 0.0959392721889741 0.271089644563134 TPR/MPHOSPH8 2 GO:0033623 regulation of integrin activation 2/580 17/18722 0.0959392721889741 0.271089644563134 FERMT1/JAM3 2 GO:0036035 osteoclast development 2/580 17/18722 0.0959392721889741 0.271089644563134 FBN1/ATP6AP1 2 GO:0042448 progesterone metabolic process 2/580 17/18722 0.0959392721889741 0.271089644563134 EGR1/ADM 2 GO:0044539 long-chain fatty acid import into cell 2/580 17/18722 0.0959392721889741 0.271089644563134 SLC2A1/SLC27A2 2 GO:0060977 coronary vasculature morphogenesis 2/580 17/18722 0.0959392721889741 0.271089644563134 LRP2/TGFBR3 2 GO:0061158 3'-UTR-mediated mRNA destabilization 2/580 17/18722 0.0959392721889741 0.271089644563134 ZFP36L1/HNRNPD 2 GO:0061450 trophoblast cell migration 2/580 17/18722 0.0959392721889741 0.271089644563134 ITGB4/GJA1 2 GO:0070206 protein trimerization 2/580 17/18722 0.0959392721889741 0.271089644563134 SLC1A5/MIF 2 GO:0070293 renal absorption 2/580 17/18722 0.0959392721889741 0.271089644563134 CLDN4/MAGED2 2 GO:0070875 positive regulation of glycogen metabolic process 2/580 17/18722 0.0959392721889741 0.271089644563134 HMGB1/IGF2 2 GO:0071816 tail-anchored membrane protein insertion into ER membrane 2/580 17/18722 0.0959392721889741 0.271089644563134 EMC1/EMC10 2 GO:0072673 lamellipodium morphogenesis 2/580 17/18722 0.0959392721889741 0.271089644563134 KANK1/WASF2 2 GO:0090083 regulation of inclusion body assembly 2/580 17/18722 0.0959392721889741 0.271089644563134 HSPA1A/DNAJB1 2 GO:0090136 epithelial cell-cell adhesion 2/580 17/18722 0.0959392721889741 0.271089644563134 ITGB5/DSP 2 GO:0090713 immunological memory process 2/580 17/18722 0.0959392721889741 0.271089644563134 CD46/CD81 2 GO:0120261 regulation of heterochromatin organization 2/580 17/18722 0.0959392721889741 0.271089644563134 TPR/MPHOSPH8 2 GO:0140354 lipid import into cell 2/580 17/18722 0.0959392721889741 0.271089644563134 SLC2A1/SLC27A2 2 GO:1902358 sulfate transmembrane transport 2/580 17/18722 0.0959392721889741 0.271089644563134 SLC26A2/SLC13A4 2 GO:1903540 establishment of protein localization to postsynaptic membrane 2/580 17/18722 0.0959392721889741 0.271089644563134 VAMP2/RAB11A 2 GO:2000811 negative regulation of anoikis 2/580 17/18722 0.0959392721889741 0.271089644563134 ITGB1/CAV1 2 GO:0010522 regulation of calcium ion transport into cytosol 6/580 102/18722 0.0970853038277806 0.274161352825141 DIAPH1/CALM1/GSTO1/CAV1/CALM2/CYBA 6 GO:0030902 hindbrain development 8/580 151/18722 0.0977925707226387 0.275823678854453 HSPA5/NAGLU/ITGB1/WLS/NCSTN/SLC6A4/BMP7/HNRNPD 8 GO:1904064 positive regulation of cation transmembrane transport 8/580 151/18722 0.0977925707226387 0.275823678854453 AKAP9/KCNN4/SLC9A1/CALM1/KIF5B/GSTO1/TMSB4X/CALM2 8 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 5/580 79/18722 0.0982934618100327 0.27675881673337 P4HB/PRKDC/CUX1/TRIOBP/CDC42 5 GO:0051279 regulation of release of sequestered calcium ion into cytosol 5/580 79/18722 0.0982934618100327 0.27675881673337 DIAPH1/CALM1/GSTO1/CALM2/CYBA 5 GO:0016051 carbohydrate biosynthetic process 10/580 202/18722 0.0983026371196574 0.27675881673337 CHST12/DDB1/ISYNA1/TPI1/MPDU1/AGL/PTGES3/PGP/IGF2/UGP2 10 GO:0003203 endocardial cushion morphogenesis 3/580 36/18722 0.0996178047404596 0.278700119954711 ISL1/TBX3/BMP7 3 GO:0003230 cardiac atrium development 3/580 36/18722 0.0996178047404596 0.278700119954711 SOX4/GJA5/ISL1 3 GO:0008207 C21-steroid hormone metabolic process 3/580 36/18722 0.0996178047404596 0.278700119954711 EGR1/ADM/DHRS2 3 GO:0009225 nucleotide-sugar metabolic process 3/580 36/18722 0.0996178047404596 0.278700119954711 EXTL2/MGAT1/UGP2 3 GO:0010092 specification of animal organ identity 3/580 36/18722 0.0996178047404596 0.278700119954711 LRP2/ISL1/GLI3 3 GO:0017004 cytochrome complex assembly 3/580 36/18722 0.0996178047404596 0.278700119954711 PET100/COX20/CYBA 3 GO:0030224 monocyte differentiation 3/580 36/18722 0.0996178047404596 0.278700119954711 JUN/ZFP36L1/CDK6 3 GO:0046466 membrane lipid catabolic process 3/580 36/18722 0.0996178047404596 0.278700119954711 HEXA/FUCA1/NEU1 3 GO:0051955 regulation of amino acid transport 3/580 36/18722 0.0996178047404596 0.278700119954711 ITGB1/SLC43A2/ARL6IP5 3 GO:0070873 regulation of glycogen metabolic process 3/580 36/18722 0.0996178047404596 0.278700119954711 PHLDA2/HMGB1/IGF2 3 GO:0002011 morphogenesis of an epithelial sheet 4/580 57/18722 0.0999033944107006 0.278700119954711 DAG1/FERMT1/BMP7/RHOA 4 GO:0051205 protein insertion into membrane 4/580 57/18722 0.0999033944107006 0.278700119954711 EGFR/EMC1/EMC10/CCDC47 4 GO:0051785 positive regulation of nuclear division 4/580 57/18722 0.0999033944107006 0.278700119954711 LRP5/PHIP/IGF2/ANAPC11 4 GO:0061756 leukocyte adhesion to vascular endothelial cell 4/580 57/18722 0.0999033944107006 0.278700119954711 ITGB1/NFAT5/ROCK1/RHOA 4 GO:0035270 endocrine system development 7/580 127/18722 0.099950935300894 0.278700119954711 CDH1/SOX4/ISL1/PBX1/CITED2/CDK6/ARID5B 7 GO:0051224 negative regulation of protein transport 7/580 127/18722 0.099950935300894 0.278700119954711 LMAN1/ERP29/FERMT1/HMGCR/OS9/FRMD4A/TXN 7 GO:0014013 regulation of gliogenesis 6/580 103/18722 0.100556687304112 0.279506521134179 LRP2/EGFR/SPINT1/DAG1/UFL1/IL6ST 6 GO:0030593 neutrophil chemotaxis 6/580 103/18722 0.100556687304112 0.279506521134179 CSF3R/BSG/DPP4/JAM3/PPIA/S100A9 6 GO:0050773 regulation of dendrite development 6/580 103/18722 0.100556687304112 0.279506521134179 IQGAP1/CUX1/BMP7/ID1/RHOA/YWHAH 6 GO:0030509 BMP signaling pathway 8/580 152/18722 0.100600713046359 0.279506521134179 FBN1/LRP2/EGR1/CRIM1/TGFBR3/GPC3/BMP7/FSTL1 8 GO:0051092 positive regulation of NF-kappaB transcription factor activity 8/580 152/18722 0.100600713046359 0.279506521134179 APP/HSPA1A/TFRC/NPM1/PPIA/CAV1/S100A9/PRKCZ 8 GO:0098754 detoxification 8/580 152/18722 0.100600713046359 0.279506521134179 MGST3/SOD3/BMP7/GSTO1/TXN/GPX3/S100A9/GPX1 8 GO:0006643 membrane lipid metabolic process 10/580 203/18722 0.100708342836209 0.279638508973855 HEXA/GPAA1/PSAP/PLPP3/SERINC1/HACD3/FUCA1/NEU1/ORMDL1/DEGS1 10 GO:0009791 post-embryonic development 5/580 80/18722 0.10233494827952 0.283816245943975 FBN1/EFEMP1/ATRX/ARID5B/CCDC47 5 GO:0071229 cellular response to acid chemical 5/580 80/18722 0.10233494827952 0.283816245943975 PLEC/SLC38A9/XBP1/HNRNPD/CYBA 5 GO:0046634 regulation of alpha-beta T cell activation 6/580 104/18722 0.104092703743064 0.28557634813859 GLI3/CD81/CD55/PRKCZ/RHOA/HMGB1 6 GO:0030217 T cell differentiation 12/580 257/18722 0.104277983097698 0.28557634813859 CTSL/EGR1/RPS6/CD46/SOX4/ZFP36L1/GLI3/PRKDC/XBP1/PRKCZ/RHOA/HMGB1 12 GO:0006874 cellular calcium ion homeostasis 19/580 448/18722 0.104617008293609 0.28557634813859 TPT1/ATP2B1/LRP1/HSP90B1/ITGAV/APP/GJA1/DDIT3/ADM/DIAPH1/CALM1/GSTO1/CAV1/CCDC47/CD55/CALM2/HMGB1/YWHAE/CYBA 19 GO:0002763 positive regulation of myeloid leukocyte differentiation 4/580 58/18722 0.104825460335789 0.28557634813859 JUN/FOS/ZFP36L1/ATP6AP1 4 GO:0010559 regulation of glycoprotein biosynthetic process 4/580 58/18722 0.104825460335789 0.28557634813859 NCSTN/TCF7L2/ITM2B/TMEM59 4 GO:0018208 peptidyl-proline modification 4/580 58/18722 0.104825460335789 0.28557634813859 P4HB/NKTR/PPIA/PPIG 4 GO:0042743 hydrogen peroxide metabolic process 4/580 58/18722 0.104825460335789 0.28557634813859 EGFR/GPX3/GPX1/CYBA 4 GO:0045604 regulation of epidermal cell differentiation 4/580 58/18722 0.104825460335789 0.28557634813859 ZFP36L1/ROCK1/NCOA3/SRSF6 4 GO:1902808 positive regulation of cell cycle G1/S phase transition 4/580 58/18722 0.104825460335789 0.28557634813859 EGFR/ADAMTS1/EIF4G1/CCND3 4 GO:0010950 positive regulation of endopeptidase activity 9/580 179/18722 0.105148834262621 0.28557634813859 CTSD/NCSTN/PMAIP1/ASPH/LGMN/S100A9/ARL6IP5/RHOA/HMGB1 9 GO:0002076 osteoblast development 2/580 18/18722 0.105798764220531 0.28557634813859 JUND/LRP5 2 GO:0002544 chronic inflammatory response 2/580 18/18722 0.105798764220531 0.28557634813859 GJA1/S100A9 2 GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 2/580 18/18722 0.105798764220531 0.28557634813859 CD46/CD55 2 GO:0003128 heart field specification 2/580 18/18722 0.105798764220531 0.28557634813859 LRP2/ISL1 2 GO:0008272 sulfate transport 2/580 18/18722 0.105798764220531 0.28557634813859 SLC26A2/SLC13A4 2 GO:0010985 negative regulation of lipoprotein particle clearance 2/580 18/18722 0.105798764220531 0.28557634813859 LRPAP1/MYLIP 2 GO:0015936 coenzyme A metabolic process 2/580 18/18722 0.105798764220531 0.28557634813859 HMGCR/CROT 2 GO:0030206 chondroitin sulfate biosynthetic process 2/580 18/18722 0.105798764220531 0.28557634813859 CHPF/CHST12 2 GO:0030728 ovulation 2/580 18/18722 0.105798764220531 0.28557634813859 ADAMTS1/HPGD 2 GO:0034134 toll-like receptor 2 signaling pathway 2/580 18/18722 0.105798764220531 0.28557634813859 HMGB1/CYBA 2 GO:0034162 toll-like receptor 9 signaling pathway 2/580 18/18722 0.105798764220531 0.28557634813859 RTN4/HMGB1 2 GO:0035743 CD4-positive, alpha-beta T cell cytokine production 2/580 18/18722 0.105798764220531 0.28557634813859 CD81/PRKCZ 2 GO:0043217 myelin maintenance 2/580 18/18722 0.105798764220531 0.28557634813859 PLEC/DEGS1 2 GO:0048486 parasympathetic nervous system development 2/580 18/18722 0.105798764220531 0.28557634813859 NRP2/TFAP2A 2 GO:0048643 positive regulation of skeletal muscle tissue development 2/580 18/18722 0.105798764220531 0.28557634813859 HMGCR/IGF2 2 GO:0051382 kinetochore assembly 2/580 18/18722 0.105798764220531 0.28557634813859 CENPF/CENPN 2 GO:0051782 negative regulation of cell division 2/580 18/18722 0.105798764220531 0.28557634813859 ASPM/TXNIP 2 GO:0060008 Sertoli cell differentiation 2/580 18/18722 0.105798764220531 0.28557634813859 CTSV/ATRX 2 GO:0060973 cell migration involved in heart development 2/580 18/18722 0.105798764220531 0.28557634813859 FOLR1/BMP7 2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis 2/580 18/18722 0.105798764220531 0.28557634813859 LGR4/MAGED1 2 GO:0098877 neurotransmitter receptor transport to plasma membrane 2/580 18/18722 0.105798764220531 0.28557634813859 VAMP2/RAB11A 2 GO:1900006 positive regulation of dendrite development 2/580 18/18722 0.105798764220531 0.28557634813859 IQGAP1/BMP7 2 GO:1900242 regulation of synaptic vesicle endocytosis 2/580 18/18722 0.105798764220531 0.28557634813859 ROCK1/CALM1 2 GO:1900424 regulation of defense response to bacterium 2/580 18/18722 0.105798764220531 0.28557634813859 GRN/CYBA 2 GO:1901673 regulation of mitotic spindle assembly 2/580 18/18722 0.105798764220531 0.28557634813859 HSPA1A/TPR 2 GO:1902683 regulation of receptor localization to synapse 2/580 18/18722 0.105798764220531 0.28557634813859 DAG1/PRKCZ 2 GO:2000136 regulation of cell proliferation involved in heart morphogenesis 2/580 18/18722 0.105798764220531 0.28557634813859 ISL1/TBX3 2 GO:0002369 T cell cytokine production 3/580 37/18722 0.106039637332906 0.28557634813859 CD81/CD55/PRKCZ 3 GO:0002724 regulation of T cell cytokine production 3/580 37/18722 0.106039637332906 0.28557634813859 CD81/CD55/PRKCZ 3 GO:0006862 nucleotide transport 3/580 37/18722 0.106039637332906 0.28557634813859 GJA1/SLC19A1/SLC25A36 3 GO:0016202 regulation of striated muscle tissue development 3/580 37/18722 0.106039637332906 0.28557634813859 HMGCR/CENPF/IGF2 3 GO:0033260 nuclear DNA replication 3/580 37/18722 0.106039637332906 0.28557634813859 ATRX/PCNA/GMNN 3 GO:0043403 skeletal muscle tissue regeneration 3/580 37/18722 0.106039637332906 0.28557634813859 DAG1/CD81/GPX1 3 GO:0045730 respiratory burst 3/580 37/18722 0.106039637332906 0.28557634813859 GRN/CD55/CYBA 3 GO:0048009 insulin-like growth factor receptor signaling pathway 3/580 37/18722 0.106039637332906 0.28557634813859 CRIM1/IGF1R/PHIP 3 GO:0048846 axon extension involved in axon guidance 3/580 37/18722 0.106039637332906 0.28557634813859 NRP2/SEMA6A/SEMA6D 3 GO:0051294 establishment of spindle orientation 3/580 37/18722 0.106039637332906 0.28557634813859 ITGB1/GJA1/DYNLT1 3 GO:0060416 response to growth hormone 3/580 37/18722 0.106039637332906 0.28557634813859 CSH1/LEPROT/CACYBP 3 GO:1902284 neuron projection extension involved in neuron projection guidance 3/580 37/18722 0.106039637332906 0.28557634813859 NRP2/SEMA6A/SEMA6D 3 GO:1905332 positive regulation of morphogenesis of an epithelium 3/580 37/18722 0.106039637332906 0.28557634813859 LGR4/GJA1/MAGED1 3 GO:0007093 mitotic cell cycle checkpoint signaling 7/580 129/18722 0.106274125728134 0.285919480398254 DUSP1/SOX4/PPP1R10/PRKDC/CENPF/TPR/CDK1 7 GO:0007605 sensory perception of sound 8/580 154/18722 0.106351473035687 0.285919480398254 LRP2/DDIT3/DIAPH1/NIPBL/TRIOBP/NDUFB9/TFAP2A/GPX1 8 GO:0030856 regulation of epithelial cell differentiation 8/580 154/18722 0.106351473035687 0.285919480398254 ZFP36L1/BTG1/ROCK1/TBX3/CAV1/NCOA3/SRSF6/ID1 8 GO:0001942 hair follicle development 5/580 81/18722 0.106457926729099 0.286040333458718 LAMA5/EGFR/LGR5/LGR4/FERMT1 5 GO:0048562 embryonic organ morphogenesis 13/580 285/18722 0.107052894680663 0.287472871339356 FBN1/FBN2/EFEMP1/NAGLU/FOLR1/GLI3/TBX3/CITED2/NIPBL/BMP7/TRIOBP/TFAP2A/SLC39A1 13 GO:0000041 transition metal ion transport 6/580 105/18722 0.107692784247835 0.288857635257601 SLC39A10/FTH1/TFRC/SLC40A1/SLC39A7/SLC39A1 6 GO:2001022 positive regulation of response to DNA damage stimulus 6/580 105/18722 0.107692784247835 0.288857635257601 EGFR/PRKDC/PMAIP1/FUS/HMGB1/PCNA 6 GO:0006665 sphingolipid metabolic process 8/580 155/18722 0.109293668104122 0.292982622681425 HEXA/PSAP/PLPP3/SERINC1/HACD3/NEU1/ORMDL1/DEGS1 8 GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 7/580 130/18722 0.109514604096806 0.293236858753163 LMAN1/TRIP11/TMED9/TMED1/COPA/TMED4/LMAN2 7 GO:0043467 regulation of generation of precursor metabolites and energy 7/580 130/18722 0.109514604096806 0.293236858753163 APP/IL10RB/PHLDA2/RHOA/HMGB1/IGF2/CDK1 7 GO:0019369 arachidonic acid metabolic process 4/580 59/18722 0.109855814396377 0.293306195612831 PTGES2/CYP2J2/PTGES3/GPX1 4 GO:0030042 actin filament depolymerization 4/580 59/18722 0.109855814396377 0.293306195612831 SPTAN1/SPTBN1/CFL1/TRIOBP 4 GO:0043407 negative regulation of MAP kinase activity 4/580 59/18722 0.109855814396377 0.293306195612831 DUSP1/HMGCR/BMP7/CAV1 4 GO:0051353 positive regulation of oxidoreductase activity 4/580 59/18722 0.109855814396377 0.293306195612831 CALM1/POR/GNAI2/CYBA 4 GO:2001258 negative regulation of cation channel activity 4/580 59/18722 0.109855814396377 0.293306195612831 CALM1/GSTO1/CAV1/CALM2 4 GO:0009205 purine ribonucleoside triphosphate metabolic process 5/580 82/18722 0.110661301932815 0.295117956014634 ALDOA/ENO1/TMSB4X/RHOA/RAN 5 GO:0060395 SMAD protein signal transduction 5/580 82/18722 0.110661301932815 0.295117956014634 JUN/LRP1/FOS/SPTBN1/BMP7 5 GO:0051091 positive regulation of DNA-binding transcription factor activity 12/580 260/18722 0.110966613667874 0.29576259035489 APP/PLPP3/HSPA1A/LRP5/DDIT3/TFRC/NPM1/PPIA/CAV1/ARID5B/S100A9/PRKCZ 12 GO:0006605 protein targeting 14/580 314/18722 0.11118980125251 0.296187723725901 TCAF1/HSPA5/LMAN1/SIL1/GCC2/OS9/SEC62/NUCB1/STOM/SSR2/LEPROT/HSPA8/UBE2L3/YWHAQ 14 GO:0002062 chondrocyte differentiation 6/580 106/18722 0.111356321078417 0.2962919046543 GLG1/EFEMP1/SERPINH1/GLI3/TRIP11/POR 6 GO:0042116 macrophage activation 6/580 106/18722 0.111356321078417 0.2962919046543 GRN/JUND/APP/CTSC/MIF/HMGB1 6 GO:0001825 blastocyst formation 3/580 38/18722 0.112618791199045 0.297438953927746 RTN4/CITED2/JUNB 3 GO:0006882 cellular zinc ion homeostasis 3/580 38/18722 0.112618791199045 0.297438953927746 SLC39A10/SLC39A7/S100A9 3 GO:0007094 mitotic spindle assembly checkpoint signaling 3/580 38/18722 0.112618791199045 0.297438953927746 DUSP1/CENPF/TPR 3 GO:0010613 positive regulation of cardiac muscle hypertrophy 3/580 38/18722 0.112618791199045 0.297438953927746 SLC9A1/ROCK1/IL6ST 3 GO:0032373 positive regulation of sterol transport 3/580 38/18722 0.112618791199045 0.297438953927746 LRP1/CAV1/NFKBIA 3 GO:0032376 positive regulation of cholesterol transport 3/580 38/18722 0.112618791199045 0.297438953927746 LRP1/CAV1/NFKBIA 3 GO:0071173 spindle assembly checkpoint signaling 3/580 38/18722 0.112618791199045 0.297438953927746 DUSP1/CENPF/TPR 3 GO:0071174 mitotic spindle checkpoint signaling 3/580 38/18722 0.112618791199045 0.297438953927746 DUSP1/CENPF/TPR 3 GO:0071392 cellular response to estradiol stimulus 3/580 38/18722 0.112618791199045 0.297438953927746 EGFR/NCOA3/HNRNPD 3 GO:0098926 postsynaptic signal transduction 3/580 38/18722 0.112618791199045 0.297438953927746 GNAQ/GNAI2/RGS10 3 GO:0099622 cardiac muscle cell membrane repolarization 3/580 38/18722 0.112618791199045 0.297438953927746 AKAP9/GJA5/YWHAE 3 GO:1901031 regulation of response to reactive oxygen species 3/580 38/18722 0.112618791199045 0.297438953927746 MET/BMP7/TXN 3 GO:1903580 positive regulation of ATP metabolic process 3/580 38/18722 0.112618791199045 0.297438953927746 APP/ENO1/TMSB4X 3 GO:1904950 negative regulation of establishment of protein localization 7/580 131/18722 0.112807176762583 0.297767411533923 LMAN1/ERP29/FERMT1/HMGCR/OS9/FRMD4A/TXN 7 GO:1901215 negative regulation of neuron death 10/580 208/18722 0.113246909909985 0.298622302290789 LRP1/GRN/SERPINF1/ISL1/TMEM259/ERBB3/EIF4G1/LGMN/RASA1/RHOA 10 GO:0018105 peptidyl-serine phosphorylation 14/580 315/18722 0.11325945844785 0.298622302290789 AKAP9/EGFR/APP/PRKDC/ROCK1/TFRC/PKN2/NSD1/EIF4G1/CAV1/MIF/TXN/PRKCZ/CDK1 14 GO:0050808 synapse organization 18/580 426/18722 0.114658307817063 0.301186342852179 NRP2/DAG1/CDH1/APP/MYH10/PTPRF/TPBG/IGF1R/DLG5/EIF4G1/CFL1/WASF2/ACTG1/LGMN/PFN1/HSPA8/RHOA/CDC42 18 GO:1903131 mononuclear cell differentiation 18/580 426/18722 0.114658307817063 0.301186342852179 JUN/CTSL/EGR1/RPS6/CD46/ITGB1/SOX4/ZFP36L1/PBX1/GLI3/PRKDC/HECTD1/CDK6/XBP1/PRKCZ/RHOA/HMGB1/DHRS2 18 GO:0046785 microtubule polymerization 5/580 83/18722 0.114943921190077 0.301186342852179 AKAP9/CLIP1/MET/HSPA1A/STMN1 5 GO:0051899 membrane depolarization 5/580 83/18722 0.114943921190077 0.301186342852179 JUN/GJA5/CAV1/PRKCZ/YWHAH 5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 4/580 60/18722 0.114992081743284 0.301186342852179 RBM25/HNRNPA1/SRSF6/TRA2B 4 GO:0006893 Golgi to plasma membrane transport 4/580 60/18722 0.114992081743284 0.301186342852179 GOLGA4/MACF1/SPTBN1/VAMP2 4 GO:0030071 regulation of mitotic metaphase/anaphase transition 4/580 60/18722 0.114992081743284 0.301186342852179 DUSP1/CENPF/TPR/ANAPC11 4 GO:0055008 cardiac muscle tissue morphogenesis 4/580 60/18722 0.114992081743284 0.301186342852179 LRP2/TGFBR3/ISL1/DSP 4 GO:0042303 molting cycle 6/580 107/18722 0.115082668656951 0.301186342852179 LAMA5/EGFR/LGR5/LGR4/FERMT1/NIPBL 6 GO:0042633 hair cycle 6/580 107/18722 0.115082668656951 0.301186342852179 LAMA5/EGFR/LGR5/LGR4/FERMT1/NIPBL 6 GO:0002281 macrophage activation involved in immune response 2/580 19/18722 0.115915621093399 0.301186342852179 GRN/HMGB1 2 GO:0006007 glucose catabolic process 2/580 19/18722 0.115915621093399 0.301186342852179 ENO1/LRP5 2 GO:0006071 glycerol metabolic process 2/580 19/18722 0.115915621093399 0.301186342852179 TPI1/PGP 2 GO:0006491 N-glycan processing 2/580 19/18722 0.115915621093399 0.301186342852179 GANAB/MAN1A2 2 GO:0007530 sex determination 2/580 19/18722 0.115915621093399 0.301186342852179 SF1/CITED2 2 GO:0033194 response to hydroperoxide 2/580 19/18722 0.115915621093399 0.301186342852179 GPX3/GPX1 2 GO:0044003 modulation by symbiont of host process 2/580 19/18722 0.115915621093399 0.301186342852179 DAG1/SERPINB9 2 GO:0045019 negative regulation of nitric oxide biosynthetic process 2/580 19/18722 0.115915621093399 0.301186342852179 CAV1/DYNLL1 2 GO:0046716 muscle cell cellular homeostasis 2/580 19/18722 0.115915621093399 0.301186342852179 GAA/ALDOA 2 GO:0051444 negative regulation of ubiquitin-protein transferase activity 2/580 19/18722 0.115915621093399 0.301186342852179 RPS20/RPL23 2 GO:0061323 cell proliferation involved in heart morphogenesis 2/580 19/18722 0.115915621093399 0.301186342852179 ISL1/TBX3 2 GO:0086014 atrial cardiac muscle cell action potential 2/580 19/18722 0.115915621093399 0.301186342852179 GJA5/GJA1 2 GO:0086026 atrial cardiac muscle cell to AV node cell signaling 2/580 19/18722 0.115915621093399 0.301186342852179 GJA5/GJA1 2 GO:0086066 atrial cardiac muscle cell to AV node cell communication 2/580 19/18722 0.115915621093399 0.301186342852179 GJA5/GJA1 2 GO:1903978 regulation of microglial cell activation 2/580 19/18722 0.115915621093399 0.301186342852179 GRN/CTSC 2 GO:1904406 negative regulation of nitric oxide metabolic process 2/580 19/18722 0.115915621093399 0.301186342852179 CAV1/DYNLL1 2 GO:0006970 response to osmotic stress 5/580 84/18722 0.119304576739348 0.308042255554277 EGFR/SLC2A1/ZFP36L1/NFAT5/MARVELD3 5 GO:0022404 molting cycle process 5/580 84/18722 0.119304576739348 0.308042255554277 LAMA5/EGFR/LGR5/LGR4/FERMT1 5 GO:0022405 hair cycle process 5/580 84/18722 0.119304576739348 0.308042255554277 LAMA5/EGFR/LGR5/LGR4/FERMT1 5 GO:0061157 mRNA destabilization 5/580 84/18722 0.119304576739348 0.308042255554277 ZFP36L1/TNRC6A/ROCK1/PUM1/HNRNPD 5 GO:0010463 mesenchymal cell proliferation 3/580 39/18722 0.119348988283983 0.308042255554277 LRP5/GPC3/BMP7 3 GO:0014742 positive regulation of muscle hypertrophy 3/580 39/18722 0.119348988283983 0.308042255554277 SLC9A1/ROCK1/IL6ST 3 GO:0031577 spindle checkpoint signaling 3/580 39/18722 0.119348988283983 0.308042255554277 DUSP1/CENPF/TPR 3 GO:0071548 response to dexamethasone 3/580 39/18722 0.119348988283983 0.308042255554277 EGFR/SERPINF1/PCNA 3 GO:0090224 regulation of spindle organization 3/580 39/18722 0.119348988283983 0.308042255554277 DYNC1H1/HSPA1A/TPR 3 GO:1901861 regulation of muscle tissue development 3/580 39/18722 0.119348988283983 0.308042255554277 HMGCR/CENPF/IGF2 3 GO:2000249 regulation of actin cytoskeleton reorganization 3/580 39/18722 0.119348988283983 0.308042255554277 IQGAP2/CDC42/PHPT1 3 GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 3/580 39/18722 0.119348988283983 0.308042255554277 CD81/CD55/PRKCZ 3 GO:0006997 nucleus organization 7/580 133/18722 0.119546965413609 0.308359556879297 PLEC/SF1/RTN4/TPR/CDK1/HMGB2/SERBP1 7 GO:0070661 leukocyte proliferation 14/580 318/18722 0.11960452388954 0.308359556879297 SLC39A10/RPS6/CD46/NCSTN/PURA/DLG5/TFRC/CD81/IL6ST/MIF/CD55/CCND3/HMGB1/IGF2 14 GO:0031334 positive regulation of protein-containing complex assembly 11/580 237/18722 0.119778253175786 0.30863637424963 AKAP9/IQGAP2/CLIP1/MET/HSPA1A/FERMT1/TFRC/EIF4G1/WASF2/PFN1/RHOA 11 GO:0030865 cortical cytoskeleton organization 4/580 61/18722 0.120231805089692 0.309376826872542 RHOB/PLEC/ROCK1/RHOA 4 GO:0043030 regulation of macrophage activation 4/580 61/18722 0.120231805089692 0.309376826872542 GRN/JUND/CTSC/MIF 4 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 12/580 264/18722 0.120265169422824 0.309376826872542 EGFR/APP/IQGAP1/ISL1/ERBB3/CSH1/CD81/CAV1/IL6ST/MIF/PRKCZ/IGF2 12 GO:0050807 regulation of synapse organization 10/580 211/18722 0.121174102179575 0.311542702729246 NRP2/DAG1/APP/TPBG/DLG5/EIF4G1/CFL1/HSPA8/RHOA/CDC42 10 GO:0030522 intracellular receptor signaling pathway 12/580 265/18722 0.122657237706107 0.314997524317648 UFL1/HSPA1A/ISL1/ESRRA/CITED2/NR2F2/PUM1/NR2F6/PTGES3/NFKBIA/RHOA/YWHAH 12 GO:0002456 T cell mediated immunity 6/580 109/18722 0.122721030759746 0.314997524317648 CD46/CTSC/CD81/CD55/PRKCZ/HMGB1 6 GO:0032410 negative regulation of transporter activity 6/580 109/18722 0.122721030759746 0.314997524317648 CALM1/C4orf3/GSTO1/CAV1/CALM2/YWHAE 6 GO:0008277 regulation of G protein-coupled receptor signaling pathway 7/580 134/18722 0.122993298293259 0.3155222450976 MET/ADM/ROCK1/GNAI2/STMN1/RGS10/DYNLT1 7 GO:0032092 positive regulation of protein binding 5/580 85/18722 0.123742008182947 0.316918546287933 LRP1/APP/TCF7L2/CAV1/RAN 5 GO:0045069 regulation of viral genome replication 5/580 85/18722 0.123742008182947 0.316918546287933 DDB1/HACD3/PKN2/PPIA/MPHOSPH8 5 GO:0098773 skin epidermis development 5/580 85/18722 0.123742008182947 0.316918546287933 LAMA5/EGFR/LGR5/LGR4/FERMT1 5 GO:0072593 reactive oxygen species metabolic process 11/580 239/18722 0.124860607261648 0.317092983143718 EGFR/SOD3/PMAIP1/BMP7/GPX3/TFAP2A/GNAI2/GPX1/RHOA/VDAC1/CYBA 11 GO:0055074 calcium ion homeostasis 19/580 460/18722 0.125450253988357 0.317092983143718 TPT1/ATP2B1/LRP1/HSP90B1/ITGAV/APP/GJA1/DDIT3/ADM/DIAPH1/CALM1/GSTO1/CAV1/CCDC47/CD55/CALM2/HMGB1/YWHAE/CYBA 19 GO:0007091 metaphase/anaphase transition of mitotic cell cycle 4/580 62/18722 0.125572451172439 0.317092983143718 DUSP1/CENPF/TPR/ANAPC11 4 GO:0009311 oligosaccharide metabolic process 4/580 62/18722 0.125572451172439 0.317092983143718 GAA/MANBA/NEU1/MPDU1 4 GO:0032731 positive regulation of interleukin-1 beta production 4/580 62/18722 0.125572451172439 0.317092983143718 EGR1/APP/ISL1/HMGB1 4 GO:0048002 antigen processing and presentation of peptide antigen 4/580 62/18722 0.125572451172439 0.317092983143718 CTSL/CTSD/CTSV/LGMN 4 GO:0031297 replication fork processing 3/580 40/18722 0.126223891163426 0.317092983143718 BOD1L1/ATRX/PCNA 3 GO:0045841 negative regulation of mitotic metaphase/anaphase transition 3/580 40/18722 0.126223891163426 0.317092983143718 DUSP1/CENPF/TPR 3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 3/580 40/18722 0.126223891163426 0.317092983143718 CALM1/GSTO1/CALM2 3 GO:0055069 zinc ion homeostasis 3/580 40/18722 0.126223891163426 0.317092983143718 SLC39A10/SLC39A7/S100A9 3 GO:0071276 cellular response to cadmium ion 3/580 40/18722 0.126223891163426 0.317092983143718 JUN/FOS/EGFR 3 GO:0072210 metanephric nephron development 3/580 40/18722 0.126223891163426 0.317092983143718 EGR1/LGR4/IRX2 3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle 2/580 20/18722 0.126264503285781 0.317092983143718 BRD4/E2F4 2 GO:0003215 cardiac right ventricle morphogenesis 2/580 20/18722 0.126264503285781 0.317092983143718 SOX4/ISL1 2 GO:0006700 C21-steroid hormone biosynthetic process 2/580 20/18722 0.126264503285781 0.317092983143718 EGR1/ADM 2 GO:0007194 negative regulation of adenylate cyclase activity 2/580 20/18722 0.126264503285781 0.317092983143718 AKAP9/GNAI2 2 GO:0009129 pyrimidine nucleoside monophosphate metabolic process 2/580 20/18722 0.126264503285781 0.317092983143718 DUT/TYMS 2 GO:0010042 response to manganese ion 2/580 20/18722 0.126264503285781 0.317092983143718 HSPA5/APP 2 GO:0010893 positive regulation of steroid biosynthetic process 2/580 20/18722 0.126264503285781 0.317092983143718 ADM/POR 2 GO:0032211 negative regulation of telomere maintenance via telomerase 2/580 20/18722 0.126264503285781 0.317092983143718 HNRNPA1/HNRNPC 2 GO:0032332 positive regulation of chondrocyte differentiation 2/580 20/18722 0.126264503285781 0.317092983143718 GLI3/POR 2 GO:0042359 vitamin D metabolic process 2/580 20/18722 0.126264503285781 0.317092983143718 LRP2/LGMN 2 GO:0043586 tongue development 2/580 20/18722 0.126264503285781 0.317092983143718 EGFR/GLI3 2 GO:0045844 positive regulation of striated muscle tissue development 2/580 20/18722 0.126264503285781 0.317092983143718 HMGCR/IGF2 2 GO:0048025 negative regulation of mRNA splicing, via spliceosome 2/580 20/18722 0.126264503285781 0.317092983143718 NPM1/SRSF6 2 GO:0048636 positive regulation of muscle organ development 2/580 20/18722 0.126264503285781 0.317092983143718 HMGCR/IGF2 2 GO:0060252 positive regulation of glial cell proliferation 2/580 20/18722 0.126264503285781 0.317092983143718 EGFR/UFL1 2 GO:0071731 response to nitric oxide 2/580 20/18722 0.126264503285781 0.317092983143718 TXN/HNRNPD 2 GO:0072567 chemokine (C-X-C motif) ligand 2 production 2/580 20/18722 0.126264503285781 0.317092983143718 LRP1/HMGB1 2 GO:1901679 nucleotide transmembrane transport 2/580 20/18722 0.126264503285781 0.317092983143718 SLC19A1/SLC25A36 2 GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 2/580 20/18722 0.126264503285781 0.317092983143718 PPIA/GPX1 2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 2/580 20/18722 0.126264503285781 0.317092983143718 HSPA1A/XBP1 2 GO:1903206 negative regulation of hydrogen peroxide-induced cell death 2/580 20/18722 0.126264503285781 0.317092983143718 MET/TXN 2 GO:1904292 regulation of ERAD pathway 2/580 20/18722 0.126264503285781 0.317092983143718 TMEM259/CAV1 2 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production 2/580 20/18722 0.126264503285781 0.317092983143718 LRP1/HMGB1 2 GO:2000678 negative regulation of transcription regulatory region DNA binding 2/580 20/18722 0.126264503285781 0.317092983143718 DDIT3/TMSB4X 2 GO:0014812 muscle cell migration 6/580 110/18722 0.126631574318993 0.317843201380269 LRP1/SEMA6D/IQGAP1/ADAMTS1/ROCK1/RHOA 6 GO:0010948 negative regulation of cell cycle process 13/580 294/18722 0.127044516332757 0.318707683637354 DUSP1/SOX4/ZFP36L1/PPP1R10/PRKDC/ATRX/NPM1/CENPF/EIF2AK4/BMP7/TPR/CTDSPL/CDK1 13 GO:0009798 axis specification 5/580 86/18722 0.128254904917912 0.321224320287135 WLS/DDIT3/TBX3/GPC3/CITED2 5 GO:0035023 regulation of Rho protein signal transduction 5/580 86/18722 0.128254904917912 0.321224320287135 ADGRG1/ITGB1/KANK1/MET/STMN1 5 GO:2000117 negative regulation of cysteine-type endopeptidase activity 5/580 86/18722 0.128254904917912 0.321224320287135 DHCR24/POR/SIAH2/GPX1/SERPINB9 5 GO:0043010 camera-type eye development 14/580 322/18722 0.128380257681291 0.321365219846978 FBN1/FBN2/ATP2B1/TENM3/EFEMP1/NAGLU/SERPINF1/LRP5/CRYBG3/FAT1/GLI3/CITED2/BMP7/TFAP2A 14 GO:0044242 cellular lipid catabolic process 10/580 214/18722 0.129399604806937 0.323742636878464 LRP1/HEXA/ILVBL/SLC27A2/FUCA1/NEU1/CROT/ECHDC2/ACADVL/HADHA 10 GO:0043401 steroid hormone mediated signaling pathway 7/580 136/18722 0.130036448935938 0.325047480085786 UFL1/ISL1/ESRRA/BMP7/PTGES3/RHOA/YWHAH 7 GO:0006813 potassium ion transport 11/580 241/18722 0.130060924626886 0.325047480085786 AKAP9/KCNN4/ITGB1/GJA5/SLC12A9/SLC9A1/KIF5B/VAMP2/CAV1/FXYD3/YWHAE 11 GO:0032233 positive regulation of actin filament bundle assembly 4/580 63/18722 0.131011417068077 0.326545605993369 ID1/PFN1/RHOA/CDC42 4 GO:0046902 regulation of mitochondrial membrane permeability 4/580 63/18722 0.131011417068077 0.326545605993369 HSPA1A/SLC9A1/PMAIP1/DYNLT1 4 GO:0050854 regulation of antigen receptor-mediated signaling pathway 4/580 63/18722 0.131011417068077 0.326545605993369 SLC39A10/KCNN4/CD81/PHPT1 4 GO:1902099 regulation of metaphase/anaphase transition of cell cycle 4/580 63/18722 0.131011417068077 0.326545605993369 DUSP1/CENPF/TPR/ANAPC11 4 GO:2000242 negative regulation of reproductive process 4/580 63/18722 0.131011417068077 0.326545605993369 SERPINF1/DUSP1/GJA1/BMP7 4 GO:0044070 regulation of anion transport 5/580 87/18722 0.132841908568072 0.330322949708749 TCAF1/ITGB1/GABRE/SLC43A2/ARL6IP5 5 GO:0061014 positive regulation of mRNA catabolic process 5/580 87/18722 0.132841908568072 0.330322949708749 ZFP36L1/TNRC6A/ROCK1/PUM1/HNRNPD 5 GO:0032733 positive regulation of interleukin-10 production 3/580 41/18722 0.133237121834791 0.330322949708749 CD46/PRKCZ/HMGB1 3 GO:0044786 cell cycle DNA replication 3/580 41/18722 0.133237121834791 0.330322949708749 ATRX/PCNA/GMNN 3 GO:0048634 regulation of muscle organ development 3/580 41/18722 0.133237121834791 0.330322949708749 HMGCR/CENPF/IGF2 3 GO:0050856 regulation of T cell receptor signaling pathway 3/580 41/18722 0.133237121834791 0.330322949708749 KCNN4/CD81/PHPT1 3 GO:0051693 actin filament capping 3/580 41/18722 0.133237121834791 0.330322949708749 SPTAN1/SPTBN1/TRIOBP 3 GO:0060612 adipose tissue development 3/580 41/18722 0.133237121834791 0.330322949708749 LRP5/ARID5B/XBP1 3 GO:0070296 sarcoplasmic reticulum calcium ion transport 3/580 41/18722 0.133237121834791 0.330322949708749 CALM1/GSTO1/CALM2 3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 3/580 41/18722 0.133237121834791 0.330322949708749 P4HB/TRIOBP/CDC42 3 GO:0045471 response to ethanol 7/580 137/18722 0.133632238310334 0.331126020448249 HMGCR/EEF1B2/TUFM/TYMS/RHOA/HPGD/CDK1 7 GO:0006633 fatty acid biosynthetic process 8/580 163/18722 0.134399412966767 0.332849664381488 ACSS1/HACD3/PTGES2/MIF/XBP1/DEGS1/ACADVL/PTGES3 8 GO:0002821 positive regulation of adaptive immune response 6/580 112/18722 0.134631455478119 0.333246886337803 TFRC/CD81/EIF2AK4/IL6ST/CD55/PRKCZ 6 GO:0051480 regulation of cytosolic calcium ion concentration 15/580 353/18722 0.135761967726987 0.334750563577176 ATP2B1/LRP1/ITGAV/GJA1/DDIT3/ADM/DIAPH1/CALM1/GSTO1/CAV1/CD55/CALM2/HMGB1/YWHAE/CYBA 15 GO:0030888 regulation of B cell proliferation 4/580 64/18722 0.136546036356644 0.334750563577176 SLC39A10/TFRC/CD81/MIF 4 GO:0045670 regulation of osteoclast differentiation 4/580 64/18722 0.136546036356644 0.334750563577176 FBN1/FOS/ESRRA/ATP6AP1 4 GO:0098930 axonal transport 4/580 64/18722 0.136546036356644 0.334750563577176 ARMCX3/DYNC1H1/DST/KIF5B 4 GO:1903018 regulation of glycoprotein metabolic process 4/580 64/18722 0.136546036356644 0.334750563577176 NCSTN/TCF7L2/ITM2B/TMEM59 4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen 2/580 21/18722 0.136821389453582 0.334750563577176 COX6A1/COX8C 2 GO:0007350 blastoderm segmentation 2/580 21/18722 0.136821389453582 0.334750563577176 NRP2/TBX3 2 GO:0010988 regulation of low-density lipoprotein particle clearance 2/580 21/18722 0.136821389453582 0.334750563577176 CNPY2/MYLIP 2 GO:0030449 regulation of complement activation 2/580 21/18722 0.136821389453582 0.334750563577176 CD46/CD55 2 GO:0032288 myelin assembly 2/580 21/18722 0.136821389453582 0.334750563577176 ITGB4/GPC1 2 GO:0034035 purine ribonucleoside bisphosphate metabolic process 2/580 21/18722 0.136821389453582 0.334750563577176 SLC26A2/TPST2 2 GO:0035330 regulation of hippo signaling 2/580 21/18722 0.136821389453582 0.334750563577176 DLG5/VGLL4 2 GO:0046514 ceramide catabolic process 2/580 21/18722 0.136821389453582 0.334750563577176 HEXA/NEU1 2 GO:0046641 positive regulation of alpha-beta T cell proliferation 2/580 21/18722 0.136821389453582 0.334750563577176 CD81/CD55 2 GO:0048485 sympathetic nervous system development 2/580 21/18722 0.136821389453582 0.334750563577176 NRP2/SOX4 2 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process 2/580 21/18722 0.136821389453582 0.334750563577176 SLC26A2/TPST2 2 GO:0071498 cellular response to fluid shear stress 2/580 21/18722 0.136821389453582 0.334750563577176 PLEC/TFPI2 2 GO:0090026 positive regulation of monocyte chemotaxis 2/580 21/18722 0.136821389453582 0.334750563577176 LGMN/HMGB1 2 GO:1901863 positive regulation of muscle tissue development 2/580 21/18722 0.136821389453582 0.334750563577176 HMGCR/IGF2 2 GO:1902307 positive regulation of sodium ion transmembrane transport 2/580 21/18722 0.136821389453582 0.334750563577176 SLC9A1/KIF5B 2 GO:1902473 regulation of protein localization to synapse 2/580 21/18722 0.136821389453582 0.334750563577176 DAG1/PRKCZ 2 GO:0051216 cartilage development 9/580 190/18722 0.136822365375234 0.334750563577176 GLG1/EFEMP1/SERPINH1/ESRRA/GLI3/TRIP11/POR/BMP7/TYMS 9 GO:0009144 purine nucleoside triphosphate metabolic process 5/580 88/18722 0.137501615412753 0.335882359918443 ALDOA/ENO1/TMSB4X/RHOA/RAN 5 GO:0031110 regulation of microtubule polymerization or depolymerization 5/580 88/18722 0.137501615412753 0.335882359918443 AKAP9/CLIP1/MET/HSPA1A/STMN1 5 GO:0050779 RNA destabilization 5/580 88/18722 0.137501615412753 0.335882359918443 ZFP36L1/TNRC6A/ROCK1/PUM1/HNRNPD 5 GO:0050806 positive regulation of synaptic transmission 8/580 164/18722 0.137728814094464 0.336260742442704 EGFR/APP/NCSTN/KIF5B/EIF2AK4/VAMP2/LGMN/PRKCZ 8 GO:0070374 positive regulation of ERK1 and ERK2 cascade 10/580 217/18722 0.137918541105364 0.33654728996907 LRP1/EGFR/APP/TPBG/ATP6AP1/HMGCR/MIF/GNAI2/PRKCZ/HMGB1 10 GO:0000280 nuclear division 18/580 439/18722 0.139405351354833 0.339997005323193 DUSP1/HSPA1A/SLC2A8/LRP5/ATRX/PHIP/CENPF/NIPBL/BMP7/ASPM/TPR/RHOA/RAN/IGF2/CDC42/ANAPC11/RANBP1/RAB11A 18 GO:0000413 protein peptidyl-prolyl isomerization 3/580 42/18722 0.14038227912617 0.34023865566223 NKTR/PPIA/PPIG 3 GO:0014912 negative regulation of smooth muscle cell migration 3/580 42/18722 0.14038227912617 0.34023865566223 LRP1/SEMA6D/RHOA 3 GO:0016601 Rac protein signal transduction 3/580 42/18722 0.14038227912617 0.34023865566223 HACD3/WASF2/DYNLT1 3 GO:0030574 collagen catabolic process 3/580 42/18722 0.14038227912617 0.34023865566223 CTSL/ITGB1/MMP15 3 GO:0032467 positive regulation of cytokinesis 3/580 42/18722 0.14038227912617 0.34023865566223 PKN2/RHOA/CDC42 3 GO:0035019 somatic stem cell population maintenance 3/580 42/18722 0.14038227912617 0.34023865566223 SOX4/LRP5/BMP7 3 GO:0045687 positive regulation of glial cell differentiation 3/580 42/18722 0.14038227912617 0.34023865566223 SPINT1/DAG1/IL6ST 3 GO:0046688 response to copper ion 3/580 42/18722 0.14038227912617 0.34023865566223 APP/SOD3/CDK1 3 GO:0051602 response to electrical stimulus 3/580 42/18722 0.14038227912617 0.34023865566223 AKAP9/SLC9A1/HNRNPD 3 GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle 3/580 42/18722 0.14038227912617 0.34023865566223 DUSP1/CENPF/TPR 3 GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II 3/580 42/18722 0.14038227912617 0.34023865566223 JUN/FOS/EGR1 3 GO:2001222 regulation of neuron migration 3/580 42/18722 0.14038227912617 0.34023865566223 SEMA6A/ADGRG1/NIPBL 3 GO:0050803 regulation of synapse structure or activity 10/580 218/18722 0.140822430298372 0.34112766839465 NRP2/DAG1/APP/TPBG/DLG5/EIF4G1/CFL1/HSPA8/RHOA/CDC42 10 GO:0030216 keratinocyte differentiation 7/580 139/18722 0.140969502229593 0.341306171197208 PLEC/ZFP36L1/ROCK1/DSP/NCOA3/SRSF6/TXNIP 7 GO:0003170 heart valve development 4/580 65/18722 0.142173585127053 0.342226448026481 SOX4/GJA5/ROCK1/HECTD1 4 GO:0010965 regulation of mitotic sister chromatid separation 4/580 65/18722 0.142173585127053 0.342226448026481 DUSP1/CENPF/TPR/ANAPC11 4 GO:0033692 cellular polysaccharide biosynthetic process 4/580 65/18722 0.142173585127053 0.342226448026481 AGL/PTGES3/IGF2/UGP2 4 GO:0044784 metaphase/anaphase transition of cell cycle 4/580 65/18722 0.142173585127053 0.342226448026481 DUSP1/CENPF/TPR/ANAPC11 4 GO:0045682 regulation of epidermis development 4/580 65/18722 0.142173585127053 0.342226448026481 ZFP36L1/ROCK1/NCOA3/SRSF6 4 GO:0060389 pathway-restricted SMAD protein phosphorylation 4/580 65/18722 0.142173585127053 0.342226448026481 LRP1/TGFBR3/BMP7/CSNK2B 4 GO:0071677 positive regulation of mononuclear cell migration 4/580 65/18722 0.142173585127053 0.342226448026481 APP/LGMN/RHOA/HMGB1 4 GO:0090307 mitotic spindle assembly 4/580 65/18722 0.142173585127053 0.342226448026481 HSPA1A/TPR/RHOA/RAB11A 4 GO:0009199 ribonucleoside triphosphate metabolic process 5/580 89/18722 0.142232578807824 0.342226448026481 ALDOA/ENO1/TMSB4X/RHOA/RAN 5 GO:0014910 regulation of smooth muscle cell migration 5/580 89/18722 0.142232578807824 0.342226448026481 LRP1/SEMA6D/IQGAP1/ADAMTS1/RHOA 5 GO:0046330 positive regulation of JNK cascade 5/580 89/18722 0.142232578807824 0.342226448026481 GADD45B/APP/GADD45G/HMGB1/CDC42 5 GO:0051781 positive regulation of cell division 5/580 89/18722 0.142232578807824 0.342226448026481 YBX1/PKN2/RHOA/IGF2/CDC42 5 GO:0002286 T cell activation involved in immune response 6/580 114/18722 0.142864113644371 0.343036134517278 RPS6/CD46/CD81/EIF2AK4/PRKCZ/HMGB1 6 GO:0022904 respiratory electron transport chain 6/580 114/18722 0.142864113644371 0.343036134517278 COX6A1/PLEC/NDUFB9/UQCRH/COX8C/CDK1 6 GO:0046660 female sex differentiation 6/580 114/18722 0.142864113644371 0.343036134517278 LRP2/HSPA5/ADAMTS1/TBX3/NR2F2/ARID5B 6 GO:0051261 protein depolymerization 6/580 114/18722 0.142864113644371 0.343036134517278 SPTAN1/SPTBN1/CFL1/TRIOBP/HSPA8/STMN1 6 GO:0071216 cellular response to biotic stimulus 11/580 246/18722 0.14356991608053 0.344552982296462 HSPA5/DDIT3/PABPN1/XBP1/CCDC47/CD55/NFKBIA/RHOA/HMGB1/TXNIP/HMGB2 11 GO:0050768 negative regulation of neurogenesis 7/580 140/18722 0.144709813267864 0.347109510834882 SEMA6A/SEMA6D/RTN4/BMP7/ID1/YWHAH/DYNLT1 7 GO:0050727 regulation of inflammatory response 16/580 386/18722 0.14682762228452 0.348627663277303 NEAT1/EGFR/GRN/APP/SERPINF1/UFL1/CTSC/ISL1/CD81/BRD4/IL6ST/TMSB4X/NINJ1/NFKBIA/S100A9/GPX1 16 GO:0051209 release of sequestered calcium ion into cytosol 6/580 115/18722 0.14706551509376 0.348627663277303 DDIT3/DIAPH1/CALM1/GSTO1/CALM2/CYBA 6 GO:0002320 lymphoid progenitor cell differentiation 2/580 22/18722 0.147563519308672 0.348627663277303 SOX4/PRKDC 2 GO:0006907 pinocytosis 2/580 22/18722 0.147563519308672 0.348627663277303 CAV1/CDC42 2 GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization 2/580 22/18722 0.147563519308672 0.348627663277303 SPESP1/FOLR1 2 GO:0007398 ectoderm development 2/580 22/18722 0.147563519308672 0.348627663277303 TPT1/ITGA6 2 GO:0016137 glycoside metabolic process 2/580 22/18722 0.147563519308672 0.348627663277303 GUSB/FUCA1 2 GO:0019400 alditol metabolic process 2/580 22/18722 0.147563519308672 0.348627663277303 TPI1/PGP 2 GO:0032891 negative regulation of organic acid transport 2/580 22/18722 0.147563519308672 0.348627663277303 SLC43A2/ARL6IP5 2 GO:0033617 mitochondrial cytochrome c oxidase assembly 2/580 22/18722 0.147563519308672 0.348627663277303 PET100/COX20 2 GO:0035809 regulation of urine volume 2/580 22/18722 0.147563519308672 0.348627663277303 ADM/GNAI2 2 GO:0048169 regulation of long-term neuronal synaptic plasticity 2/580 22/18722 0.147563519308672 0.348627663277303 APP/RAB11A 2 GO:0051220 cytoplasmic sequestering of protein 2/580 22/18722 0.147563519308672 0.348627663277303 TMSB4X/NFKBIA 2 GO:0060444 branching involved in mammary gland duct morphogenesis 2/580 22/18722 0.147563519308672 0.348627663277303 LRP5/TBX3 2 GO:0060965 negative regulation of gene silencing by miRNA 2/580 22/18722 0.147563519308672 0.348627663277303 NEAT1/KCNQ1OT1 2 GO:0071359 cellular response to dsRNA 2/580 22/18722 0.147563519308672 0.348627663277303 NPM1/CAV1 2 GO:0071404 cellular response to low-density lipoprotein particle stimulus 2/580 22/18722 0.147563519308672 0.348627663277303 ITGB1/CD81 2 GO:1900120 regulation of receptor binding 2/580 22/18722 0.147563519308672 0.348627663277303 PTPRF/PHLDA2 2 GO:1901032 negative regulation of response to reactive oxygen species 2/580 22/18722 0.147563519308672 0.348627663277303 MET/TXN 2 GO:2000114 regulation of establishment of cell polarity 2/580 22/18722 0.147563519308672 0.348627663277303 KANK1/ROCK1 2 GO:0022411 cellular component disassembly 18/580 443/18722 0.147590180422419 0.348627663277303 LRP1/LAMC1/UFL1/RPL23/SPTAN1/SPTBN1/MMP15/CTSV/IGF1R/DPP4/CALM1/KIF5B/CFL1/TRIOBP/HSPA8/VDAC1/STMN1/CDK1 18 GO:0001504 neurotransmitter uptake 3/580 43/18722 0.147652954798983 0.348627663277303 ITGB1/SLC38A1/SLC6A4 3 GO:0030517 negative regulation of axon extension 3/580 43/18722 0.147652954798983 0.348627663277303 SEMA6A/SEMA6D/RTN4 3 GO:0033046 negative regulation of sister chromatid segregation 3/580 43/18722 0.147652954798983 0.348627663277303 DUSP1/CENPF/TPR 3 GO:0033048 negative regulation of mitotic sister chromatid segregation 3/580 43/18722 0.147652954798983 0.348627663277303 DUSP1/CENPF/TPR 3 GO:0034142 toll-like receptor 4 signaling pathway 3/580 43/18722 0.147652954798983 0.348627663277303 NINJ1/NFKBIA/HMGB1 3 GO:0045981 positive regulation of nucleotide metabolic process 3/580 43/18722 0.147652954798983 0.348627663277303 APP/ENO1/TMSB4X 3 GO:0120178 steroid hormone biosynthetic process 3/580 43/18722 0.147652954798983 0.348627663277303 EGR1/ADM/HSD17B1 3 GO:1900544 positive regulation of purine nucleotide metabolic process 3/580 43/18722 0.147652954798983 0.348627663277303 APP/ENO1/TMSB4X 3 GO:2000816 negative regulation of mitotic sister chromatid separation 3/580 43/18722 0.147652954798983 0.348627663277303 DUSP1/CENPF/TPR 3 GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 4/580 66/18722 0.147891287818989 0.348627663277303 PRKDC/TFRC/HMGB1/HMGB2 4 GO:0016444 somatic cell DNA recombination 4/580 66/18722 0.147891287818989 0.348627663277303 PRKDC/TFRC/HMGB1/HMGB2 4 GO:0042446 hormone biosynthetic process 4/580 66/18722 0.147891287818989 0.348627663277303 EGR1/ADM/POR/HSD17B1 4 GO:1902476 chloride transmembrane transport 4/580 66/18722 0.147891287818989 0.348627663277303 SLC26A2/GABRE/SLC12A9/PCYOX1 4 GO:0051283 negative regulation of sequestering of calcium ion 6/580 116/18722 0.151322390716687 0.35630534159223 DDIT3/DIAPH1/CALM1/GSTO1/CALM2/CYBA 6 GO:0000070 mitotic sister chromatid segregation 8/580 168/18722 0.151454667883861 0.35630534159223 DUSP1/ATRX/CENPF/NIPBL/TPR/RAN/ANAPC11/RAB11A 8 GO:0002706 regulation of lymphocyte mediated immunity 8/580 168/18722 0.151454667883861 0.35630534159223 CD46/CADM1/TFRC/CD81/CD55/PRKCZ/SERPINB9/HMGB1 8 GO:0099173 postsynapse organization 8/580 168/18722 0.151454667883861 0.35630534159223 NRP2/IGF1R/CFL1/WASF2/ACTG1/LGMN/HSPA8/CDC42 8 GO:0051983 regulation of chromosome segregation 5/580 91/18722 0.151902288495412 0.356816941309171 DUSP1/CENPF/PUM1/TPR/ANAPC11 5 GO:0055006 cardiac cell development 5/580 91/18722 0.151902288495412 0.356816941309171 TGFBR3/PLEC/ISL1/TBX3/CDK1 5 GO:0098661 inorganic anion transmembrane transport 5/580 91/18722 0.151902288495412 0.356816941309171 SLC26A2/GABRE/SLC12A9/PCYOX1/SLC13A4 5 GO:0007009 plasma membrane organization 7/580 142/18722 0.152330726113243 0.357462263951915 PLEC/SPESP1/SPTBN1/FOLR1/CAV1/DEGS1/S100A9 7 GO:2000045 regulation of G1/S transition of mitotic cell cycle 7/580 142/18722 0.152330726113243 0.357462263951915 EGFR/SOX4/ADAMTS1/PRKDC/EIF4G1/CTDSPL/CCND3 7 GO:0006879 cellular iron ion homeostasis 4/580 67/18722 0.153696322897056 0.359036462980516 FTH1/ATP6AP1/TFRC/SLC40A1 4 GO:0010517 regulation of phospholipase activity 4/580 67/18722 0.153696322897056 0.359036462980516 LRP1/EGFR/GNAQ/PRKCZ 4 GO:0035914 skeletal muscle cell differentiation 4/580 67/18722 0.153696322897056 0.359036462980516 FOS/EGR1/GPC1/CITED2 4 GO:0051306 mitotic sister chromatid separation 4/580 67/18722 0.153696322897056 0.359036462980516 DUSP1/CENPF/TPR/ANAPC11 4 GO:0061180 mammary gland epithelium development 4/580 67/18722 0.153696322897056 0.359036462980516 LRP5/RTN4/TBX3/GPX1 4 GO:0070527 platelet aggregation 4/580 67/18722 0.153696322897056 0.359036462980516 PPIA/IL6ST/ACTG1/MYL12A 4 GO:0072665 protein localization to vacuole 4/580 67/18722 0.153696322897056 0.359036462980516 RTN4/GCC2/CD81/HSPA8 4 GO:1903317 regulation of protein maturation 4/580 67/18722 0.153696322897056 0.359036462980516 GLG1/SOX4/ENO1/TMEM59 4 GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 4/580 67/18722 0.153696322897056 0.359036462980516 CD81/CD55/PRKCZ/HMGB1 4 GO:0000075 cell cycle checkpoint signaling 8/580 169/18722 0.154985992834137 0.359832246948709 DUSP1/SOX4/PPP1R10/PRKDC/CENPF/EIF2AK4/TPR/CDK1 8 GO:0002066 columnar/cuboidal epithelial cell development 3/580 44/18722 0.155042748416515 0.359832246948709 CDK6/IL6ST/TYMS 3 GO:0008542 visual learning 3/580 44/18722 0.155042748416515 0.359832246948709 APP/ITGB1/HMGCR 3 GO:0009262 deoxyribonucleotide metabolic process 3/580 44/18722 0.155042748416515 0.359832246948709 DUT/TYMS/RRM2 3 GO:0031295 T cell costimulation 3/580 44/18722 0.155042748416515 0.359832246948709 DPP4/CD81/CAV1 3 GO:0032881 regulation of polysaccharide metabolic process 3/580 44/18722 0.155042748416515 0.359832246948709 PHLDA2/HMGB1/IGF2 3 GO:0042554 superoxide anion generation 3/580 44/18722 0.155042748416515 0.359832246948709 EGFR/GNAI2/CYBA 3 GO:0045124 regulation of bone resorption 3/580 44/18722 0.155042748416515 0.359832246948709 EGFR/ATP6AP1/TFRC 3 GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT 3/580 44/18722 0.155042748416515 0.359832246948709 IL10RB/CSH1/PRLR 3 GO:0050999 regulation of nitric-oxide synthase activity 3/580 44/18722 0.155042748416515 0.359832246948709 EGFR/CALM1/CAV1 3 GO:0060324 face development 3/580 44/18722 0.155042748416515 0.359832246948709 ANKRD11/NIPBL/ARID5B 3 GO:0150076 neuroinflammatory response 3/580 44/18722 0.155042748416515 0.359832246948709 GRN/ITGB1/CTSC 3 GO:1903214 regulation of protein targeting to mitochondrion 3/580 44/18722 0.155042748416515 0.359832246948709 LMAN1/LEPROT/UBE2L3 3 GO:0051225 spindle assembly 6/580 117/18722 0.155633776186154 0.361023787053268 DYNC1H1/HSPA1A/ASPM/TPR/RHOA/RAB11A 6 GO:0062012 regulation of small molecule metabolic process 14/580 334/18722 0.156826240813926 0.363454558246662 EGR1/APP/ENO1/DDB1/ADM/POR/PMAIP1/CAV1/TMSB4X/ACADVL/PHLDA2/PGP/HMGB1/IGF2 14 GO:0001708 cell fate specification 5/580 92/18722 0.156837948484423 0.363454558246662 ITGB1/ISL1/GLI3/LMO4/TBX3 5 GO:0002052 positive regulation of neuroblast proliferation 2/580 23/18722 0.158469338761553 0.364150639614617 GLI3/ASPM 2 GO:0002363 alpha-beta T cell lineage commitment 2/580 23/18722 0.158469338761553 0.364150639614617 CTSL/RHOA 2 GO:0006622 protein targeting to lysosome 2/580 23/18722 0.158469338761553 0.364150639614617 GCC2/HSPA8 2 GO:0009162 deoxyribonucleoside monophosphate metabolic process 2/580 23/18722 0.158469338761553 0.364150639614617 DUT/TYMS 2 GO:0010888 negative regulation of lipid storage 2/580 23/18722 0.158469338761553 0.364150639614617 ITGAV/NFKBIA 2 GO:0016973 poly(A)+ mRNA export from nucleus 2/580 23/18722 0.158469338761553 0.364150639614617 PABPN1/THOC2 2 GO:0019430 removal of superoxide radicals 2/580 23/18722 0.158469338761553 0.364150639614617 SOD3/BMP7 2 GO:0031280 negative regulation of cyclase activity 2/580 23/18722 0.158469338761553 0.364150639614617 AKAP9/GNAI2 2 GO:0045662 negative regulation of myoblast differentiation 2/580 23/18722 0.158469338761553 0.364150639614617 DDIT3/TBX3 2 GO:0051131 chaperone-mediated protein complex assembly 2/580 23/18722 0.158469338761553 0.364150639614617 HSPA1A/PTGES3 2 GO:0051383 kinetochore organization 2/580 23/18722 0.158469338761553 0.364150639614617 CENPF/CENPN 2 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization 2/580 23/18722 0.158469338761553 0.364150639614617 AKAP9/GJA5 2 GO:0060396 growth hormone receptor signaling pathway 2/580 23/18722 0.158469338761553 0.364150639614617 CSH1/LEPROT 2 GO:0060575 intestinal epithelial cell differentiation 2/580 23/18722 0.158469338761553 0.364150639614617 IL6ST/TYMS 2 GO:1904666 regulation of ubiquitin protein ligase activity 2/580 23/18722 0.158469338761553 0.364150639614617 RPS20/RPL23 2 GO:2000810 regulation of bicellular tight junction assembly 2/580 23/18722 0.158469338761553 0.364150639614617 GJA1/ROCK1 2 GO:2001169 regulation of ATP biosynthetic process 2/580 23/18722 0.158469338761553 0.364150639614617 ENO1/TMSB4X 2 GO:0002263 cell activation involved in immune response 12/580 279/18722 0.158903503022132 0.364788079396165 LRP1/GRN/APP/RPS6/CD46/TFRC/CD81/EIF2AK4/VAMP2/XBP1/PRKCZ/HMGB1 12 GO:0032984 protein-containing complex disassembly 10/580 224/18722 0.158903601130215 0.364788079396165 RPL23/SPTAN1/SPTBN1/IGF1R/CALM1/KIF5B/CFL1/TRIOBP/HSPA8/STMN1 10 GO:0009988 cell-cell recognition 4/580 68/18722 0.159585828353717 0.365452332680029 SPESP1/ALDOA/FOLR1/CD81 4 GO:0034394 protein localization to cell surface 4/580 68/18722 0.159585828353717 0.365452332680029 JAM3/UNC50/LEPROT/RAB11A 4 GO:0042987 amyloid precursor protein catabolic process 4/580 68/18722 0.159585828353717 0.365452332680029 NCSTN/DHCR24/ROCK1/RTN4 4 GO:0046637 regulation of alpha-beta T cell differentiation 4/580 68/18722 0.159585828353717 0.365452332680029 GLI3/PRKCZ/RHOA/HMGB1 4 GO:1904888 cranial skeletal system development 4/580 68/18722 0.159585828353717 0.365452332680029 GLI3/NIPBL/TFAP2A/SLC39A1 4 GO:0051282 regulation of sequestering of calcium ion 6/580 118/18722 0.159998681546557 0.366217454661928 DDIT3/DIAPH1/CALM1/GSTO1/CALM2/CYBA 6 GO:0032755 positive regulation of interleukin-6 production 5/580 93/18722 0.161838697143322 0.369519774380752 APP/ISL1/XBP1/HMGB1/CYBA 5 GO:0033273 response to vitamin 5/580 93/18722 0.161838697143322 0.369519774380752 ATP2B1/EGFR/FOLR1/BMP7/TYMS 5 GO:0090398 cellular senescence 5/580 93/18722 0.161838697143322 0.369519774380752 YBX1/PRKDC/TBX3/YPEL3/CDK6 5 GO:0106027 neuron projection organization 5/580 93/18722 0.161838697143322 0.369519774380752 APP/IGF1R/CFL1/LGMN/CDC42 5 GO:1901796 regulation of signal transduction by p53 class mediator 5/580 93/18722 0.161838697143322 0.369519774380752 RPS20/RPL23/PMAIP1/NPM1/MIF 5 GO:0050670 regulation of lymphocyte proliferation 10/580 225/18722 0.162024292904333 0.369681223545296 SLC39A10/CD46/DLG5/TFRC/CD81/IL6ST/MIF/CD55/HMGB1/IGF2 10 GO:0042129 regulation of T cell proliferation 8/580 171/18722 0.162165182886324 0.369681223545296 CD46/DLG5/TFRC/CD81/IL6ST/CD55/HMGB1/IGF2 8 GO:0030835 negative regulation of actin filament depolymerization 3/580 45/18722 0.162545281047115 0.369681223545296 SPTAN1/SPTBN1/TRIOBP 3 GO:0031670 cellular response to nutrient 3/580 45/18722 0.162545281047115 0.369681223545296 ATP2B1/FOLR1/XBP1 3 GO:0045933 positive regulation of muscle contraction 3/580 45/18722 0.162545281047115 0.369681223545296 ENO1/GSTO1/RHOA 3 GO:0051985 negative regulation of chromosome segregation 3/580 45/18722 0.162545281047115 0.369681223545296 DUSP1/CENPF/TPR 3 GO:0060119 inner ear receptor cell development 3/580 45/18722 0.162545281047115 0.369681223545296 NAGLU/TRIP11/TRIOBP 3 GO:1905819 negative regulation of chromosome separation 3/580 45/18722 0.162545281047115 0.369681223545296 DUSP1/CENPF/TPR 3 GO:0043524 negative regulation of neuron apoptotic process 7/580 145/18722 0.164103019027384 0.372859375425677 LRP1/GRN/ISL1/ERBB3/LGMN/RASA1/RHOA 7 GO:0051961 negative regulation of nervous system development 7/580 145/18722 0.164103019027384 0.372859375425677 SEMA6A/SEMA6D/RTN4/BMP7/ID1/YWHAH/DYNLT1 7 GO:0010906 regulation of glucose metabolic process 6/580 119/18722 0.164416092375741 0.373388303534947 DDB1/PMAIP1/PHLDA2/PGP/HMGB1/IGF2 6 GO:0034605 cellular response to heat 4/580 69/18722 0.165556907038342 0.375429144142043 HSPA1A/TPR/DNAJB1/YWHAE 4 GO:0050810 regulation of steroid biosynthetic process 4/580 69/18722 0.165556907038342 0.375429144142043 EGR1/SF1/ADM/POR 4 GO:0060193 positive regulation of lipase activity 4/580 69/18722 0.165556907038342 0.375429144142043 EGFR/GNAQ/PRKCZ/RHOA 4 GO:0032091 negative regulation of protein binding 5/580 94/18722 0.166902908985776 0.378112727565924 LRPAP1/PTPRF/ROCK1/CAV1/ID1 5 GO:0048704 embryonic skeletal system morphogenesis 5/580 94/18722 0.166902908985776 0.378112727565924 GLI3/NIPBL/BMP7/TFAP2A/SLC39A1 5 GO:0018209 peptidyl-serine modification 14/580 338/18722 0.166992710819551 0.378131985404934 AKAP9/EGFR/APP/PRKDC/ROCK1/TFRC/PKN2/NSD1/EIF4G1/CAV1/MIF/TXN/PRKCZ/CDK1 14 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 7/580 146/18722 0.16811528312549 0.379966408736812 ADGRG1/LGR5/LGR4/ADRB1/ADM/GNAQ/GNAI2 7 GO:0045580 regulation of T cell differentiation 7/580 146/18722 0.16811528312549 0.379966408736812 CD46/SOX4/GLI3/XBP1/PRKCZ/RHOA/HMGB1 7 GO:0048813 dendrite morphogenesis 7/580 146/18722 0.16811528312549 0.379966408736812 ITGB1/TPBG/CUX1/CFL1/ID1/YWHAH/CDC42 7 GO:0032944 regulation of mononuclear cell proliferation 10/580 227/18722 0.16835493603165 0.379966408736812 SLC39A10/CD46/DLG5/TFRC/CD81/IL6ST/MIF/CD55/HMGB1/IGF2 10 GO:0001779 natural killer cell differentiation 2/580 24/18722 0.169518447243364 0.379966408736812 PBX1/HECTD1 2 GO:0007035 vacuolar acidification 2/580 24/18722 0.169518447243364 0.379966408736812 GRN/ATP6AP2 2 GO:0009219 pyrimidine deoxyribonucleotide metabolic process 2/580 24/18722 0.169518447243364 0.379966408736812 DUT/TYMS 2 GO:0030810 positive regulation of nucleotide biosynthetic process 2/580 24/18722 0.169518447243364 0.379966408736812 ENO1/TMSB4X 2 GO:0031639 plasminogen activation 2/580 24/18722 0.169518447243364 0.379966408736812 ENO1/DHCR24 2 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress 2/580 24/18722 0.169518447243364 0.379966408736812 HSPA5/DDIT3 2 GO:0048641 regulation of skeletal muscle tissue development 2/580 24/18722 0.169518447243364 0.379966408736812 HMGCR/IGF2 2 GO:0050855 regulation of B cell receptor signaling pathway 2/580 24/18722 0.169518447243364 0.379966408736812 SLC39A10/CD81 2 GO:0051043 regulation of membrane protein ectodomain proteolysis 2/580 24/18722 0.169518447243364 0.379966408736812 ROCK1/TIMP3 2 GO:0060149 negative regulation of posttranscriptional gene silencing 2/580 24/18722 0.169518447243364 0.379966408736812 NEAT1/KCNQ1OT1 2 GO:0060561 apoptotic process involved in morphogenesis 2/580 24/18722 0.169518447243364 0.379966408736812 LRP5/BMP7 2 GO:0060967 negative regulation of gene silencing by RNA 2/580 24/18722 0.169518447243364 0.379966408736812 NEAT1/KCNQ1OT1 2 GO:0070841 inclusion body assembly 2/580 24/18722 0.169518447243364 0.379966408736812 HSPA1A/DNAJB1 2 GO:0071378 cellular response to growth hormone stimulus 2/580 24/18722 0.169518447243364 0.379966408736812 CSH1/LEPROT 2 GO:1900373 positive regulation of purine nucleotide biosynthetic process 2/580 24/18722 0.169518447243364 0.379966408736812 ENO1/TMSB4X 2 GO:1903077 negative regulation of protein localization to plasma membrane 2/580 24/18722 0.169518447243364 0.379966408736812 HECTD1/TMEM59 2 GO:2000209 regulation of anoikis 2/580 24/18722 0.169518447243364 0.379966408736812 ITGB1/CAV1 2 GO:0019693 ribose phosphate metabolic process 16/580 396/18722 0.169991661263675 0.380109135826901 GAPDH/SLC26A2/LDHA/APP/ALDOA/ENO1/TPST2/ACSS1/HMGCR/TPI1/CROT/TMSB4X/PKM/RHOA/RAN/PYGL 16 GO:0031294 lymphocyte costimulation 3/580 46/18722 0.170154207867471 0.380109135826901 DPP4/CD81/CAV1 3 GO:0031648 protein destabilization 3/580 46/18722 0.170154207867471 0.380109135826901 PRKDC/SIAH1/MYLIP 3 GO:0033047 regulation of mitotic sister chromatid segregation 3/580 46/18722 0.170154207867471 0.380109135826901 DUSP1/CENPF/TPR 3 GO:0043616 keratinocyte proliferation 3/580 46/18722 0.170154207867471 0.380109135826901 ZFP36L1/FERMT1/SRSF6 3 GO:0045851 pH reduction 3/580 46/18722 0.170154207867471 0.380109135826901 GRN/ATP6AP1/ATP6AP2 3 GO:0090329 regulation of DNA-dependent DNA replication 3/580 46/18722 0.170154207867471 0.380109135826901 ATRX/PCNA/GMNN 3 GO:0009150 purine ribonucleotide metabolic process 15/580 368/18722 0.171225300497595 0.382318229771634 GAPDH/SLC26A2/LDHA/APP/ALDOA/ENO1/TPST2/ACSS1/HMGCR/TPI1/CROT/TMSB4X/PKM/RHOA/RAN 15 GO:0060415 muscle tissue morphogenesis 4/580 70/18722 0.17160663181034 0.382802131678604 LRP2/TGFBR3/ISL1/DSP 4 GO:0070830 bicellular tight junction assembly 4/580 70/18722 0.17160663181034 0.382802131678604 CLDN4/GJA1/ROCK1/MARVELD3 4 GO:0042773 ATP synthesis coupled electron transport 5/580 95/18722 0.172028929755484 0.383009359642295 COX6A1/NDUFB9/UQCRH/COX8C/CDK1 5 GO:0042775 mitochondrial ATP synthesis coupled electron transport 5/580 95/18722 0.172028929755484 0.383009359642295 COX6A1/NDUFB9/UQCRH/COX8C/CDK1 5 GO:0042982 amyloid precursor protein metabolic process 5/580 95/18722 0.172028929755484 0.383009359642295 NCSTN/DHCR24/ROCK1/RTN4/ITM2B 5 GO:0050764 regulation of phagocytosis 5/580 95/18722 0.172028929755484 0.383009359642295 LRP1/ITGAV/LMAN2/HMGB1/CYBA 5 GO:0070588 calcium ion transmembrane transport 13/580 312/18722 0.172840393832331 0.384631900341709 ATP2B1/AHNAK/ITGAV/SLC9A1/DDIT3/DIAPH1/CALM1/C4orf3/GSTO1/CALM2/VDAC1/YWHAE/CYBA 13 GO:0048706 embryonic skeletal system development 6/580 121/18722 0.17340425739577 0.385702152629232 PBX1/GLI3/NIPBL/BMP7/TFAP2A/SLC39A1 6 GO:0010212 response to ionizing radiation 7/580 148/18722 0.176267728322259 0.391557153462053 RHOB/HSPA5/EGR1/PRKDC/NIPBL/GPX1/CYBA 7 GO:0048771 tissue remodeling 8/580 175/18722 0.176975449328214 0.391557153462053 EGFR/LGR4/LRP5/GJA1/ATP6AP1/ROCK1/TFRC/CAV1 8 GO:0050954 sensory perception of mechanical stimulus 8/580 175/18722 0.176975449328214 0.391557153462053 LRP2/DDIT3/DIAPH1/NIPBL/TRIOBP/NDUFB9/TFAP2A/GPX1 8 GO:0030510 regulation of BMP signaling pathway 5/580 96/18722 0.177215078692541 0.391557153462053 FBN1/LRP2/CRIM1/GPC3/FSTL1 5 GO:0042632 cholesterol homeostasis 5/580 96/18722 0.177215078692541 0.391557153462053 LRP5/HMGCR/CAV1/XBP1/MYLIP 5 GO:0055017 cardiac muscle tissue growth 5/580 96/18722 0.177215078692541 0.391557153462053 TGFBR3/GJA1/CITED2/VGLL4/CDK1 5 GO:0032722 positive regulation of chemokine production 4/580 71/18722 0.177732050514991 0.391557153462053 LRP1/EGR1/APP/HMGB1 4 GO:0050795 regulation of behavior 4/580 71/18722 0.177732050514991 0.391557153462053 GJA1/ADRB1/ZFHX3/EIF2AK4 4 GO:0071230 cellular response to amino acid stimulus 4/580 71/18722 0.177732050514991 0.391557153462053 SLC38A9/XBP1/HNRNPD/CYBA 4 GO:0001774 microglial cell activation 3/580 47/18722 0.177863229728288 0.391557153462053 GRN/APP/CTSC 3 GO:0007595 lactation 3/580 47/18722 0.177863229728288 0.391557153462053 PRLR/CAV1/XBP1 3 GO:0010761 fibroblast migration 3/580 47/18722 0.177863229728288 0.391557153462053 ITGB1/PLEC/ARID5B 3 GO:0045601 regulation of endothelial cell differentiation 3/580 47/18722 0.177863229728288 0.391557153462053 BTG1/ROCK1/ID1 3 GO:0046677 response to antibiotic 3/580 47/18722 0.177863229728288 0.391557153462053 HSPA5/RPL23/SLC9A1 3 GO:0047496 vesicle transport along microtubule 3/580 47/18722 0.177863229728288 0.391557153462053 DYNC1H1/KIF5B/PRKCZ 3 GO:0048483 autonomic nervous system development 3/580 47/18722 0.177863229728288 0.391557153462053 NRP2/SOX4/TFAP2A 3 GO:0050885 neuromuscular process controlling balance 3/580 47/18722 0.177863229728288 0.391557153462053 GAA/APP/IGDCC3 3 GO:0051972 regulation of telomerase activity 3/580 47/18722 0.177863229728288 0.391557153462053 PTGES3/HNRNPD/HNRNPA2B1 3 GO:0120163 negative regulation of cold-induced thermogenesis 3/580 47/18722 0.177863229728288 0.391557153462053 LGR4/DDIT3/ID1 3 GO:0002688 regulation of leukocyte chemotaxis 6/580 122/18722 0.177972870870518 0.391557153462053 DUSP1/DPP4/JAM3/MIF/LGMN/HMGB1 6 GO:0051928 positive regulation of calcium ion transport 6/580 122/18722 0.177972870870518 0.391557153462053 ATP2B1/SLC9A1/CALM1/GSTO1/CAV1/CALM2 6 GO:0072329 monocarboxylic acid catabolic process 6/580 122/18722 0.177972870870518 0.391557153462053 ILVBL/SLC27A2/CROT/ECHDC2/ACADVL/HADHA 6 GO:1990266 neutrophil migration 6/580 122/18722 0.177972870870518 0.391557153462053 CSF3R/BSG/DPP4/JAM3/PPIA/S100A9 6 GO:0060249 anatomical structure homeostasis 13/580 314/18722 0.178382481414477 0.392272775914295 ATP2B1/EGFR/GAA/LAMC1/ITGB1/SLC2A1/ALDOA/GJA1/LSR/ATP6AP1/TFRC/JAM3/ACTG1 13 GO:0045165 cell fate commitment 11/580 258/18722 0.178829299414735 0.393069504526432 CTSL/ITGB1/ISL1/GLI3/PRKDC/LMO4/TBX3/TCF7L2/NR2F2/RHOA/CDC42 11 GO:0032496 response to lipopolysaccharide 14/580 343/18722 0.18016152840949 0.394166317602531 JUN/FOS/JUND/GJA1/ADM/PABPN1/XBP1/CD55/NFKBIA/S100A9/RHOA/HPGD/HMGB1/HMGB2 14 GO:0009147 pyrimidine nucleoside triphosphate metabolic process 2/580 25/18722 0.180691547125168 0.394166317602531 DUT/TYMS 2 GO:0010560 positive regulation of glycoprotein biosynthetic process 2/580 25/18722 0.180691547125168 0.394166317602531 NCSTN/TCF7L2 2 GO:0016540 protein autoprocessing 2/580 25/18722 0.180691547125168 0.394166317602531 CTSL/PISD 2 GO:0032469 endoplasmic reticulum calcium ion homeostasis 2/580 25/18722 0.180691547125168 0.394166317602531 APP/CCDC47 2 GO:0032878 regulation of establishment or maintenance of cell polarity 2/580 25/18722 0.180691547125168 0.394166317602531 KANK1/ROCK1 2 GO:0033622 integrin activation 2/580 25/18722 0.180691547125168 0.394166317602531 FERMT1/JAM3 2 GO:0045109 intermediate filament organization 2/580 25/18722 0.180691547125168 0.394166317602531 PLEC/DSP 2 GO:0046039 GTP metabolic process 2/580 25/18722 0.180691547125168 0.394166317602531 RHOA/RAN 2 GO:0051450 myoblast proliferation 2/580 25/18722 0.180691547125168 0.394166317602531 MALAT1/GPX1 2 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 2/580 25/18722 0.180691547125168 0.394166317602531 HSPA1A/NFKBIA 2 GO:0071450 cellular response to oxygen radical 2/580 25/18722 0.180691547125168 0.394166317602531 SOD3/BMP7 2 GO:0071451 cellular response to superoxide 2/580 25/18722 0.180691547125168 0.394166317602531 SOD3/BMP7 2 GO:0072012 glomerulus vasculature development 2/580 25/18722 0.180691547125168 0.394166317602531 EGR1/BMP7 2 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell 2/580 25/18722 0.180691547125168 0.394166317602531 NFAT5/RHOA 2 GO:1905564 positive regulation of vascular endothelial cell proliferation 2/580 25/18722 0.180691547125168 0.394166317602531 HMGB1/IGF2 2 GO:0043534 blood vessel endothelial cell migration 8/580 176/18722 0.180769029336959 0.394166317602531 ITGB1/EPHB4/TMSB4X/ID1/GPX1/RHOA/HMGB1/CSNK2B 8 GO:0010596 negative regulation of endothelial cell migration 5/580 97/18722 0.182459650765959 0.397108018583283 SERPINF1/NR2F2/RHOA/HMGB1/CSNK2B 5 GO:0014909 smooth muscle cell migration 5/580 97/18722 0.182459650765959 0.397108018583283 LRP1/SEMA6D/IQGAP1/ADAMTS1/RHOA 5 GO:0035335 peptidyl-tyrosine dephosphorylation 5/580 97/18722 0.182459650765959 0.397108018583283 DUSP1/DUSP6/PTPRF/PTPRA/PGP 5 GO:0055092 sterol homeostasis 5/580 97/18722 0.182459650765959 0.397108018583283 LRP5/HMGCR/CAV1/XBP1/MYLIP 5 GO:0000271 polysaccharide biosynthetic process 4/580 72/18722 0.183930190781202 0.398815532551687 AGL/PTGES3/IGF2/UGP2 4 GO:0001736 establishment of planar polarity 4/580 72/18722 0.183930190781202 0.398815532551687 ZNRF3/GPC3/RHOA/CDC42 4 GO:0007164 establishment of tissue polarity 4/580 72/18722 0.183930190781202 0.398815532551687 ZNRF3/GPC3/RHOA/CDC42 4 GO:0033045 regulation of sister chromatid segregation 4/580 72/18722 0.183930190781202 0.398815532551687 DUSP1/CENPF/TPR/ANAPC11 4 GO:0035567 non-canonical Wnt signaling pathway 4/580 72/18722 0.183930190781202 0.398815532551687 ZNRF3/GPC3/RHOA/CDC42 4 GO:0042246 tissue regeneration 4/580 72/18722 0.183930190781202 0.398815532551687 DAG1/CD81/NINJ1/GPX1 4 GO:0043903 regulation of biological process involved in symbiotic interaction 4/580 72/18722 0.183930190781202 0.398815532551687 ITGAV/P4HB/DDB1/CAV1 4 GO:1905818 regulation of chromosome separation 4/580 72/18722 0.183930190781202 0.398815532551687 DUSP1/CENPF/TPR/ANAPC11 4 GO:0043405 regulation of MAP kinase activity 8/580 177/18722 0.184597891154907 0.400076790196399 EGFR/DUSP1/IQGAP1/ERP29/HMGCR/MAGED1/BMP7/CAV1 8 GO:0002686 negative regulation of leukocyte migration 3/580 48/18722 0.185666103741606 0.40108362680084 DUSP1/DPP4/MIF 3 GO:0033628 regulation of cell adhesion mediated by integrin 3/580 48/18722 0.185666103741606 0.40108362680084 FERMT1/DPP4/JAM3 3 GO:0035036 sperm-egg recognition 3/580 48/18722 0.185666103741606 0.40108362680084 SPESP1/ALDOA/FOLR1 3 GO:0045005 DNA-dependent DNA replication maintenance of fidelity 3/580 48/18722 0.185666103741606 0.40108362680084 BOD1L1/ATRX/PCNA 3 GO:0048146 positive regulation of fibroblast proliferation 3/580 48/18722 0.185666103741606 0.40108362680084 PRKDC/CDK6/MIF 3 GO:1903053 regulation of extracellular matrix organization 3/580 48/18722 0.185666103741606 0.40108362680084 LRP1/DAG1/DPP4 3 GO:1905710 positive regulation of membrane permeability 3/580 48/18722 0.185666103741606 0.40108362680084 HSPA1A/SLC9A1/JAM3 3 GO:0030098 lymphocyte differentiation 15/580 374/18722 0.186621331336245 0.402959987021762 CTSL/EGR1/RPS6/CD46/ITGB1/SOX4/ZFP36L1/PBX1/GLI3/PRKDC/HECTD1/XBP1/PRKCZ/RHOA/HMGB1 15 GO:0070301 cellular response to hydrogen peroxide 5/580 98/18722 0.187760918870018 0.405232498220164 RHOB/MET/TXN/PCNA/CDK1 5 GO:0035725 sodium ion transmembrane transport 8/580 178/18722 0.188461452165914 0.40655575789595 UTRN/SLC3A2/SLC9A1/KIF5B/SLC6A4/STOM/FXYD3/YWHAH 8 GO:0032732 positive regulation of interleukin-1 production 4/580 73/18722 0.190198064640896 0.409542221594818 EGR1/APP/ISL1/HMGB1 4 GO:0050848 regulation of calcium-mediated signaling 4/580 73/18722 0.190198064640896 0.409542221594818 NFAT5/SLC9A1/CALM1/CALM2 4 GO:0061035 regulation of cartilage development 4/580 73/18722 0.190198064640896 0.409542221594818 GLG1/EFEMP1/GLI3/POR 4 GO:1904427 positive regulation of calcium ion transmembrane transport 4/580 73/18722 0.190198064640896 0.409542221594818 SLC9A1/CALM1/GSTO1/CALM2 4 GO:0071621 granulocyte chemotaxis 6/580 125/18722 0.191963574487402 0.409754156892286 CSF3R/BSG/DPP4/JAM3/PPIA/S100A9 6 GO:0001573 ganglioside metabolic process 2/580 26/18722 0.191970395155513 0.409754156892286 HEXA/NEU1 2 GO:0007214 gamma-aminobutyric acid signaling pathway 2/580 26/18722 0.191970395155513 0.409754156892286 GABRE/GNAI2 2 GO:0008535 respiratory chain complex IV assembly 2/580 26/18722 0.191970395155513 0.409754156892286 PET100/COX20 2 GO:0014829 vascular associated smooth muscle contraction 2/580 26/18722 0.191970395155513 0.409754156892286 ATP2B1/RHOA 2 GO:0021680 cerebellar Purkinje cell layer development 2/580 26/18722 0.191970395155513 0.409754156892286 HSPA5/NAGLU 2 GO:0033598 mammary gland epithelial cell proliferation 2/580 26/18722 0.191970395155513 0.409754156892286 RTN4/GPX1 2 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 2/580 26/18722 0.191970395155513 0.409754156892286 HSPA1A/NFKBIA 2 GO:0042634 regulation of hair cycle 2/580 26/18722 0.191970395155513 0.409754156892286 FERMT1/NIPBL 2 GO:0045026 plasma membrane fusion 2/580 26/18722 0.191970395155513 0.409754156892286 SPESP1/FOLR1 2 GO:0045672 positive regulation of osteoclast differentiation 2/580 26/18722 0.191970395155513 0.409754156892286 FOS/ATP6AP1 2 GO:0046639 negative regulation of alpha-beta T cell differentiation 2/580 26/18722 0.191970395155513 0.409754156892286 GLI3/HMGB1 2 GO:0048668 collateral sprouting 2/580 26/18722 0.191970395155513 0.409754156892286 LRP1/APP 2 GO:0048843 negative regulation of axon extension involved in axon guidance 2/580 26/18722 0.191970395155513 0.409754156892286 SEMA6A/SEMA6D 2 GO:0060352 cell adhesion molecule production 2/580 26/18722 0.191970395155513 0.409754156892286 PPIA/CAV1 2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway 2/580 26/18722 0.191970395155513 0.409754156892286 ADRB1/GNAI2 2 GO:0099637 neurotransmitter receptor transport 2/580 26/18722 0.191970395155513 0.409754156892286 VAMP2/RAB11A 2 GO:1904376 negative regulation of protein localization to cell periphery 2/580 26/18722 0.191970395155513 0.409754156892286 HECTD1/TMEM59 2 GO:2000050 regulation of non-canonical Wnt signaling pathway 2/580 26/18722 0.191970395155513 0.409754156892286 ZNRF3/GPC3 2 GO:1901991 negative regulation of mitotic cell cycle phase transition 8/580 179/18722 0.192359118500572 0.410395532177137 DUSP1/SOX4/ZFP36L1/PRKDC/CENPF/TPR/CTDSPL/CDK1 8 GO:0007204 positive regulation of cytosolic calcium ion concentration 13/580 319/18722 0.192609504219665 0.410741313216718 LRP1/ITGAV/GJA1/DDIT3/ADM/DIAPH1/CALM1/GSTO1/CAV1/CD55/CALM2/HMGB1/CYBA 13 GO:0031056 regulation of histone modification 7/580 152/18722 0.193062935137375 0.411064836919 ISL1/ATRX/KDM5A/BRD4/NSD1/NIPBL/IGF2 7 GO:0033209 tumor necrosis factor-mediated signaling pathway 5/580 99/18722 0.193117135982344 0.411064836919 HSPA1A/SPPL2A/TMSB4X/KRT8/NFKBIA 5 GO:0008038 neuron recognition 3/580 49/18722 0.193556652946164 0.411064836919 APP/BSG/RTN4 3 GO:0010823 negative regulation of mitochondrion organization 3/580 49/18722 0.193556652946164 0.411064836919 HSPA1A/TFRC/GPX1 3 GO:0018198 peptidyl-cysteine modification 3/580 49/18722 0.193556652946164 0.411064836919 GAPDH/TXN/S100A9 3 GO:0043330 response to exogenous dsRNA 3/580 49/18722 0.193556652946164 0.411064836919 SLC3A2/CAV1/NFKBIA 3 GO:0051932 synaptic transmission, GABAergic 3/580 49/18722 0.193556652946164 0.411064836919 GABRE/TPBG/KIF5B 3 GO:0052372 modulation by symbiont of entry into host 3/580 49/18722 0.193556652946164 0.411064836919 ITGAV/P4HB/CAV1 3 GO:1904894 positive regulation of receptor signaling pathway via STAT 3/580 49/18722 0.193556652946164 0.411064836919 IL10RB/CSH1/PRLR 3 GO:0002437 inflammatory response to antigenic stimulus 4/580 74/18722 0.196532672970287 0.417194642622 CD81/GPX1/HMGB1/HMGB2 4 GO:0120254 olefinic compound metabolic process 7/580 153/18722 0.197359266042578 0.418758187209868 EGR1/ADM/PTGES2/HSD17B1/CYP2J2/PTGES3/GPX1 7 GO:0034655 nucleobase-containing compound catabolic process 16/580 407/18722 0.197508935874531 0.418884660625829 KCNQ1OT1/HSPA1A/ZFP36L1/TNRC6A/YBX1/ROCK1/NPM1/PUM1/FUS/MGAT1/DUT/HNRNPC/HNRNPD/CIRBP/CARHSP1/SERBP1 16 GO:0019218 regulation of steroid metabolic process 5/580 100/18722 0.198526537281746 0.420850922924977 EGR1/SF1/ADM/POR/ACADVL 5 GO:0048565 digestive tract development 6/580 127/18722 0.201516690432501 0.426001757843303 EGFR/LGR4/GLI3/NIPBL/IL6ST/TYMS 6 GO:0043268 positive regulation of potassium ion transport 3/580 50/18722 0.201528775104427 0.426001757843303 AKAP9/KCNN4/KIF5B 3 GO:0045058 T cell selection 3/580 50/18722 0.201528775104427 0.426001757843303 CTSL/GLI3/RHOA 3 GO:0046638 positive regulation of alpha-beta T cell differentiation 3/580 50/18722 0.201528775104427 0.426001757843303 GLI3/PRKCZ/RHOA 3 GO:1903747 regulation of establishment of protein localization to mitochondrion 3/580 50/18722 0.201528775104427 0.426001757843303 LMAN1/LEPROT/UBE2L3 3 GO:2000677 regulation of transcription regulatory region DNA binding 3/580 50/18722 0.201528775104427 0.426001757843303 DDIT3/NSD1/TMSB4X 3 GO:0050770 regulation of axonogenesis 7/580 154/18722 0.201692970471478 0.426001757843303 LRP1/GOLGA4/MACF1/SEMA6A/SEMA6D/RTN4/RAB11A 7 GO:0006024 glycosaminoglycan biosynthetic process 4/580 75/18722 0.202931009753696 0.426001757843303 CHPF/HEXA/CHST12/B3GAT3 4 GO:0033077 T cell differentiation in thymus 4/580 75/18722 0.202931009753696 0.426001757843303 RPS6/ZFP36L1/GLI3/PRKDC 4 GO:0003171 atrioventricular valve development 2/580 27/18722 0.203337755840063 0.426001757843303 SOX4/GJA5 2 GO:0003272 endocardial cushion formation 2/580 27/18722 0.203337755840063 0.426001757843303 TBX3/BMP7 2 GO:0010561 negative regulation of glycoprotein biosynthetic process 2/580 27/18722 0.203337755840063 0.426001757843303 ITM2B/TMEM59 2 GO:0015813 L-glutamate transmembrane transport 2/580 27/18722 0.203337755840063 0.426001757843303 ITGB1/ARL6IP5 2 GO:0018126 protein hydroxylation 2/580 27/18722 0.203337755840063 0.426001757843303 P4HB/ASPH 2 GO:0034143 regulation of toll-like receptor 4 signaling pathway 2/580 27/18722 0.203337755840063 0.426001757843303 NINJ1/HMGB1 2 GO:0034453 microtubule anchoring 2/580 27/18722 0.203337755840063 0.426001757843303 DAG1/GCC2 2 GO:0035116 embryonic hindlimb morphogenesis 2/580 27/18722 0.203337755840063 0.426001757843303 TBX3/GPC3 2 GO:0042104 positive regulation of activated T cell proliferation 2/580 27/18722 0.203337755840063 0.426001757843303 HMGB1/IGF2 2 GO:0051953 negative regulation of amine transport 2/580 27/18722 0.203337755840063 0.426001757843303 SLC43A2/ARL6IP5 2 GO:0061437 renal system vasculature development 2/580 27/18722 0.203337755840063 0.426001757843303 EGR1/BMP7 2 GO:0061440 kidney vasculature development 2/580 27/18722 0.203337755840063 0.426001757843303 EGR1/BMP7 2 GO:0099625 ventricular cardiac muscle cell membrane repolarization 2/580 27/18722 0.203337755840063 0.426001757843303 AKAP9/GJA5 2 GO:1902883 negative regulation of response to oxidative stress 2/580 27/18722 0.203337755840063 0.426001757843303 MET/TXN 2 GO:1903205 regulation of hydrogen peroxide-induced cell death 2/580 27/18722 0.203337755840063 0.426001757843303 MET/TXN 2 GO:1903319 positive regulation of protein maturation 2/580 27/18722 0.203337755840063 0.426001757843303 SOX4/ENO1 2 GO:1904357 negative regulation of telomere maintenance via telomere lengthening 2/580 27/18722 0.203337755840063 0.426001757843303 HNRNPA1/HNRNPC 2 GO:0050804 modulation of chemical synaptic transmission 17/580 439/18722 0.205047492356645 0.429390313800431 AKAP9/EGFR/CDH1/APP/ITGB1/NCSTN/CALM1/KIF5B/SLC6A4/EIF2AK4/VAMP2/PTPRA/LGMN/GNAI2/PRKCZ/YWHAH/RAB11A 17 GO:0002685 regulation of leukocyte migration 9/580 210/18722 0.205247301877803 0.429615301995347 APP/DUSP1/DPP4/JAM3/CD81/MIF/LGMN/RHOA/HMGB1 9 GO:0099177 regulation of trans-synaptic signaling 17/580 440/18722 0.207604355894617 0.434353512940111 AKAP9/EGFR/CDH1/APP/ITGB1/NCSTN/CALM1/KIF5B/SLC6A4/EIF2AK4/VAMP2/PTPRA/LGMN/GNAI2/PRKCZ/YWHAH/RAB11A 17 GO:0002819 regulation of adaptive immune response 8/580 183/18722 0.208278589058906 0.43554069353137 CD46/TFRC/CD81/EIF2AK4/IL6ST/CD55/PRKCZ/HMGB1 8 GO:0030100 regulation of endocytosis 9/580 211/18722 0.208993137507922 0.43554069353137 LRP1/ITGAV/AAK1/LRPAP1/ROCK1/CALM1/GPC3/CAV1/CDC42 9 GO:0014823 response to activity 4/580 76/18722 0.209390066171002 0.43554069353137 COL4A2/PRKDC/CDK1/CYBA 4 GO:0045685 regulation of glial cell differentiation 4/580 76/18722 0.209390066171002 0.43554069353137 SPINT1/DAG1/IL6ST/CDK1 4 GO:0006672 ceramide metabolic process 5/580 102/18722 0.209497756574382 0.43554069353137 HEXA/PLPP3/NEU1/ORMDL1/DEGS1 5 GO:0032677 regulation of interleukin-8 production 5/580 102/18722 0.209497756574382 0.43554069353137 HSPA1A/DDIT3/TMSB4X/HMGB1/ANXA4 5 GO:0035710 CD4-positive, alpha-beta T cell activation 5/580 102/18722 0.209497756574382 0.43554069353137 CTSL/CD81/CD55/PRKCZ/HMGB1 5 GO:0010656 negative regulation of muscle cell apoptotic process 3/580 51/18722 0.209576450682263 0.43554069353137 PPP1R10/HMGCR/BMP7 3 GO:0010874 regulation of cholesterol efflux 3/580 51/18722 0.209576450682263 0.43554069353137 LRP1/CAV1/NFKBIA 3 GO:0014009 glial cell proliferation 3/580 51/18722 0.209576450682263 0.43554069353137 EGFR/UFL1/SOX4 3 GO:0032873 negative regulation of stress-activated MAPK cascade 3/580 51/18722 0.209576450682263 0.43554069353137 DUSP1/MARVELD3/PPIA 3 GO:0045668 negative regulation of osteoblast differentiation 3/580 51/18722 0.209576450682263 0.43554069353137 CRIM1/LRP5/CDK6 3 GO:0046850 regulation of bone remodeling 3/580 51/18722 0.209576450682263 0.43554069353137 EGFR/ATP6AP1/TFRC 3 GO:0051339 regulation of lyase activity 3/580 51/18722 0.209576450682263 0.43554069353137 AKAP9/GNAI2/PHPT1 3 GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 3/580 51/18722 0.209576450682263 0.43554069353137 DUSP1/MARVELD3/PPIA 3 GO:0046631 alpha-beta T cell activation 7/580 156/18722 0.210469125900234 0.437200493328267 CTSL/GLI3/CD81/CD55/PRKCZ/RHOA/HMGB1 7 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 6/580 129/18722 0.211239655882706 0.438605196210029 CTSD/PMAIP1/S100A9/ARL6IP5/RHOA/HMGB1 6 GO:0000303 response to superoxide 2/580 28/18722 0.214777356689927 0.442577582702592 SOD3/BMP7 2 GO:0001945 lymph vessel development 2/580 28/18722 0.214777356689927 0.442577582702592 SVEP1/NR2F2 2 GO:0003156 regulation of animal organ formation 2/580 28/18722 0.214777356689927 0.442577582702592 CITED2/BMP7 2 GO:0007064 mitotic sister chromatid cohesion 2/580 28/18722 0.214777356689927 0.442577582702592 ATRX/NIPBL 2 GO:0010460 positive regulation of heart rate 2/580 28/18722 0.214777356689927 0.442577582702592 ADRB1/ADM 2 GO:0010575 positive regulation of vascular endothelial growth factor production 2/580 28/18722 0.214777356689927 0.442577582702592 ISL1/IL6ST 2 GO:0042983 amyloid precursor protein biosynthetic process 2/580 28/18722 0.214777356689927 0.442577582702592 NCSTN/ITM2B 2 GO:0042984 regulation of amyloid precursor protein biosynthetic process 2/580 28/18722 0.214777356689927 0.442577582702592 NCSTN/ITM2B 2 GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT 2/580 28/18722 0.214777356689927 0.442577582702592 CAV1/LEPROT 2 GO:0051503 adenine nucleotide transport 2/580 28/18722 0.214777356689927 0.442577582702592 GJA1/SLC19A1 2 GO:0051894 positive regulation of focal adhesion assembly 2/580 28/18722 0.214777356689927 0.442577582702592 IQGAP1/ROCK1 2 GO:0086011 membrane repolarization during action potential 2/580 28/18722 0.214777356689927 0.442577582702592 CAV1/YWHAE 2 GO:0099623 regulation of cardiac muscle cell membrane repolarization 2/580 28/18722 0.214777356689927 0.442577582702592 AKAP9/GJA5 2 GO:1903020 positive regulation of glycoprotein metabolic process 2/580 28/18722 0.214777356689927 0.442577582702592 NCSTN/TCF7L2 2 GO:1903672 positive regulation of sprouting angiogenesis 2/580 28/18722 0.214777356689927 0.442577582702592 PKM/HMGB1 2 GO:1903779 regulation of cardiac conduction 2/580 28/18722 0.214777356689927 0.442577582702592 ATP2B1/GJA5 2 GO:2000377 regulation of reactive oxygen species metabolic process 7/580 157/18722 0.214909862341602 0.442577582702592 EGFR/BMP7/TFAP2A/GNAI2/RHOA/VDAC1/CYBA 7 GO:0032637 interleukin-8 production 5/580 103/18722 0.215055974394293 0.442577582702592 HSPA1A/DDIT3/TMSB4X/HMGB1/ANXA4 5 GO:0032760 positive regulation of tumor necrosis factor production 5/580 103/18722 0.215055974394293 0.442577582702592 APP/ISL1/MIF/HMGB1/CYBA 5 GO:0046425 regulation of receptor signaling pathway via JAK-STAT 5/580 103/18722 0.215055974394293 0.442577582702592 IL10RB/CSH1/PRLR/CAV1/LEPROT 5 GO:0000380 alternative mRNA splicing, via spliceosome 4/580 77/18722 0.215906834510178 0.443935759198425 RBM25/HNRNPA1/SRSF6/TRA2B 4 GO:0002200 somatic diversification of immune receptors 4/580 77/18722 0.215906834510178 0.443935759198425 PRKDC/TFRC/HMGB1/HMGB2 4 GO:0009259 ribonucleotide metabolic process 15/580 385/18722 0.216505739265917 0.444970478712232 GAPDH/SLC26A2/LDHA/APP/ALDOA/ENO1/TPST2/ACSS1/HMGCR/TPI1/CROT/TMSB4X/PKM/RHOA/RAN 15 GO:0010662 regulation of striated muscle cell apoptotic process 3/580 52/18722 0.217693750059747 0.446032436796425 PPP1R10/HMGCR/BMP7 3 GO:0010718 positive regulation of epithelial to mesenchymal transition 3/580 52/18722 0.217693750059747 0.446032436796425 ISL1/TCF7L2/BMP7 3 GO:0030514 negative regulation of BMP signaling pathway 3/580 52/18722 0.217693750059747 0.446032436796425 FBN1/LRP2/CRIM1 3 GO:0035196 production of miRNAs involved in gene silencing by miRNA 3/580 52/18722 0.217693750059747 0.446032436796425 EGFR/PUM1/HNRNPA2B1 3 GO:0043277 apoptotic cell clearance 3/580 52/18722 0.217693750059747 0.446032436796425 LRP1/ITGAV/HMGB1 3 GO:0072132 mesenchyme morphogenesis 3/580 52/18722 0.217693750059747 0.446032436796425 ISL1/TBX3/BMP7 3 GO:2000378 negative regulation of reactive oxygen species metabolic process 3/580 52/18722 0.217693750059747 0.446032436796425 TFAP2A/RHOA/VDAC1 3 GO:0072330 monocarboxylic acid biosynthetic process 9/580 214/18722 0.220393711700777 0.451365545187281 ACSS1/SLC27A2/HACD3/PTGES2/MIF/XBP1/DEGS1/ACADVL/PTGES3 9 GO:0006892 post-Golgi vesicle-mediated transport 5/580 104/18722 0.220660179982739 0.451513637087426 GOLGA4/MACF1/SPTBN1/VAMP2/SCAMP2 5 GO:1901890 positive regulation of cell junction assembly 5/580 104/18722 0.220660179982739 0.451513637087426 IQGAP1/TPBG/ROCK1/DLG5/CAV1 5 GO:0006612 protein targeting to membrane 6/580 131/18722 0.221122859442002 0.452261398093558 TCAF1/HSPA5/SIL1/SEC62/STOM/SSR2 6 GO:0002707 negative regulation of lymphocyte mediated immunity 3/580 53/18722 0.225874840019163 0.458033535673573 CD46/CD55/SERPINB9 3 GO:0034381 plasma lipoprotein particle clearance 3/580 53/18722 0.225874840019163 0.458033535673573 LRPAP1/CNPY2/MYLIP 3 GO:0045806 negative regulation of endocytosis 3/580 53/18722 0.225874840019163 0.458033535673573 ITGAV/LRPAP1/CAV1 3 GO:0051438 regulation of ubiquitin-protein transferase activity 3/580 53/18722 0.225874840019163 0.458033535673573 RPS20/RPL23/UBE2L3 3 GO:0000305 response to oxygen radical 2/580 29/18722 0.226273845267946 0.458033535673573 SOD3/BMP7 2 GO:0001773 myeloid dendritic cell activation 2/580 29/18722 0.226273845267946 0.458033535673573 HMGB1/DHRS2 2 GO:0003209 cardiac atrium morphogenesis 2/580 29/18722 0.226273845267946 0.458033535673573 SOX4/ISL1 2 GO:0010592 positive regulation of lamellipodium assembly 2/580 29/18722 0.226273845267946 0.458033535673573 WASF2/CDC42 2 GO:0010955 negative regulation of protein processing 2/580 29/18722 0.226273845267946 0.458033535673573 GLG1/TMEM59 2 GO:0015868 purine ribonucleotide transport 2/580 29/18722 0.226273845267946 0.458033535673573 GJA1/SLC19A1 2 GO:0019082 viral protein processing 2/580 29/18722 0.226273845267946 0.458033535673573 MGAT1/CANX 2 GO:0040018 positive regulation of multicellular organism growth 2/580 29/18722 0.226273845267946 0.458033535673573 NIPBL/IGF2 2 GO:0048665 neuron fate specification 2/580 29/18722 0.226273845267946 0.458033535673573 ISL1/GLI3 2 GO:0050686 negative regulation of mRNA processing 2/580 29/18722 0.226273845267946 0.458033535673573 NPM1/SRSF6 2 GO:0060441 epithelial tube branching involved in lung morphogenesis 2/580 29/18722 0.226273845267946 0.458033535673573 DAG1/DLG5 2 GO:0060969 negative regulation of gene silencing 2/580 29/18722 0.226273845267946 0.458033535673573 NEAT1/KCNQ1OT1 2 GO:0070979 protein K11-linked ubiquitination 2/580 29/18722 0.226273845267946 0.458033535673573 ANAPC11/UBE2L3 2 GO:0071549 cellular response to dexamethasone stimulus 2/580 29/18722 0.226273845267946 0.458033535673573 EGFR/SERPINF1 2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 2/580 29/18722 0.226273845267946 0.458033535673573 TPT1/MIF 2 GO:1902430 negative regulation of amyloid-beta formation 2/580 29/18722 0.226273845267946 0.458033535673573 ROCK1/RTN4 2 GO:1903318 negative regulation of protein maturation 2/580 29/18722 0.226273845267946 0.458033535673573 GLG1/TMEM59 2 GO:1903902 positive regulation of viral life cycle 2/580 29/18722 0.226273845267946 0.458033535673573 P4HB/DDB1 2 GO:2000406 positive regulation of T cell migration 2/580 29/18722 0.226273845267946 0.458033535673573 APP/RHOA 2 GO:0040029 regulation of gene expression, epigenetic 5/580 105/18722 0.226308549769484 0.458033535673573 SERTAD1/TPR/MPHOSPH8/GPX1/IGF2 5 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 11/580 273/18722 0.227988273522562 0.461232475055865 TENM3/CLDN4/CDH1/ITGB1/BSG/CADM1/DSG2/FAT1/DSC3/PTPRF/DSC2 11 GO:0060402 calcium ion transport into cytosol 7/580 160/18722 0.228432209728 0.461929655410839 DDIT3/DIAPH1/CALM1/GSTO1/CAV1/CALM2/CYBA 7 GO:0030308 negative regulation of cell growth 8/580 188/18722 0.228869831859272 0.46261346717839 SEMA6A/SEMA6D/HSPA1A/ENO1/GJA1/BTG1/RTN4/VGLL4 8 GO:0006023 aminoglycan biosynthetic process 4/580 79/18722 0.229101503911841 0.462679589532771 CHPF/HEXA/CHST12/B3GAT3 4 GO:0050772 positive regulation of axonogenesis 4/580 79/18722 0.229101503911841 0.462679589532771 LRP1/GOLGA4/MACF1/RAB11A 4 GO:0070663 regulation of leukocyte proliferation 10/580 245/18722 0.230252706673758 0.464802664383528 SLC39A10/CD46/DLG5/TFRC/CD81/IL6ST/MIF/CD55/HMGB1/IGF2 10 GO:0001824 blastocyst development 5/580 106/18722 0.231999254160131 0.468125176181679 N4BP2L2/RTN4/CITED2/JUNB/RRM2 5 GO:0007215 glutamate receptor signaling pathway 3/580 54/18722 0.234113989553964 0.470758394040418 APP/NCSTN/GNAQ 3 GO:0030834 regulation of actin filament depolymerization 3/580 54/18722 0.234113989553964 0.470758394040418 SPTAN1/SPTBN1/TRIOBP 3 GO:0031050 dsRNA processing 3/580 54/18722 0.234113989553964 0.470758394040418 EGFR/PUM1/HNRNPA2B1 3 GO:0060350 endochondral bone morphogenesis 3/580 54/18722 0.234113989553964 0.470758394040418 SERPINH1/TRIP11/POR 3 GO:0070918 production of small RNA involved in gene silencing by RNA 3/580 54/18722 0.234113989553964 0.470758394040418 EGFR/PUM1/HNRNPA2B1 3 GO:0072348 sulfur compound transport 3/580 54/18722 0.234113989553964 0.470758394040418 SLC26A2/GJA1/SLC13A4 3 GO:1902743 regulation of lamellipodium organization 3/580 54/18722 0.234113989553964 0.470758394040418 KANK1/WASF2/CDC42 3 GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II 3/580 54/18722 0.234113989553964 0.470758394040418 JUN/FOS/EGR1 3 GO:0048145 regulation of fibroblast proliferation 4/580 80/18722 0.235773427892489 0.473690402905434 FTH1/PRKDC/CDK6/MIF 4 GO:0042445 hormone metabolic process 9/580 218/18722 0.235955455006606 0.473690402905434 CTSL/EGR1/ENPEP/ADM/POR/ATP6AP2/TCF7L2/HSD17B1/DHRS2 9 GO:0044270 cellular nitrogen compound catabolic process 17/580 451/18722 0.236672962246423 0.473690402905434 KCNQ1OT1/HSPA1A/ZFP36L1/TNRC6A/YBX1/ROCK1/POR/NPM1/PUM1/FUS/MGAT1/DUT/HNRNPC/HNRNPD/CIRBP/CARHSP1/SERBP1 17 GO:0002237 response to molecule of bacterial origin 14/580 363/18722 0.237538321169295 0.473690402905434 JUN/FOS/JUND/GJA1/ADM/PABPN1/XBP1/CD55/NFKBIA/S100A9/RHOA/HPGD/HMGB1/HMGB2 14 GO:0021761 limbic system development 5/580 107/18722 0.237730459331856 0.473690402905434 NRP2/GLI3/TBX3/KIF5B/CDK6 5 GO:0031532 actin cytoskeleton reorganization 5/580 107/18722 0.237730459331856 0.473690402905434 IQGAP2/PLEC/RHOA/CDC42/PHPT1 5 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 5/580 107/18722 0.237730459331856 0.473690402905434 APP/ISL1/MIF/HMGB1/CYBA 5 GO:0006221 pyrimidine nucleotide biosynthetic process 2/580 30/18722 0.237812747964779 0.473690402905434 DUT/TYMS 2 GO:0007202 activation of phospholipase C activity 2/580 30/18722 0.237812747964779 0.473690402905434 EGFR/GNAQ 2 GO:0015865 purine nucleotide transport 2/580 30/18722 0.237812747964779 0.473690402905434 GJA1/SLC19A1 2 GO:0019674 NAD metabolic process 2/580 30/18722 0.237812747964779 0.473690402905434 LDHA/ENO1 2 GO:0030204 chondroitin sulfate metabolic process 2/580 30/18722 0.237812747964779 0.473690402905434 CHPF/CHST12 2 GO:0031571 mitotic G1 DNA damage checkpoint signaling 2/580 30/18722 0.237812747964779 0.473690402905434 SOX4/PRKDC 2 GO:0034508 centromere complex assembly 2/580 30/18722 0.237812747964779 0.473690402905434 CENPF/CENPN 2 GO:0036296 response to increased oxygen levels 2/580 30/18722 0.237812747964779 0.473690402905434 ATP6AP1/CAV1 2 GO:0043032 positive regulation of macrophage activation 2/580 30/18722 0.237812747964779 0.473690402905434 JUND/CTSC 2 GO:0045577 regulation of B cell differentiation 2/580 30/18722 0.237812747964779 0.473690402905434 ZFP36L1/XBP1 2 GO:0045940 positive regulation of steroid metabolic process 2/580 30/18722 0.237812747964779 0.473690402905434 ADM/POR 2 GO:0045948 positive regulation of translational initiation 2/580 30/18722 0.237812747964779 0.473690402905434 PPP1R15A/EIF2AK4 2 GO:0060603 mammary gland duct morphogenesis 2/580 30/18722 0.237812747964779 0.473690402905434 LRP5/TBX3 2 GO:0090314 positive regulation of protein targeting to membrane 2/580 30/18722 0.237812747964779 0.473690402905434 TCAF1/STOM 2 GO:1903019 negative regulation of glycoprotein metabolic process 2/580 30/18722 0.237812747964779 0.473690402905434 ITM2B/TMEM59 2 GO:0072331 signal transduction by p53 class mediator 7/580 163/18722 0.242235984570463 0.481154514397063 RPS20/RPL23/SOX4/ATRX/PMAIP1/NPM1/MIF 7 GO:0003179 heart valve morphogenesis 3/580 55/18722 0.242405575040275 0.481154514397063 SOX4/GJA5/ROCK1 3 GO:0044091 membrane biogenesis 3/580 55/18722 0.242405575040275 0.481154514397063 SPTBN1/SERINC1/CAV1 3 GO:0061614 pri-miRNA transcription by RNA polymerase II 3/580 55/18722 0.242405575040275 0.481154514397063 JUN/FOS/EGR1 3 GO:0008589 regulation of smoothened signaling pathway 4/580 81/18722 0.242491116264613 0.481154514397063 GLI3/DLG5/POR/GPC3 4 GO:0010833 telomere maintenance via telomere lengthening 4/580 81/18722 0.242491116264613 0.481154514397063 HNRNPA1/PTGES3/HNRNPC/HNRNPA2B1 4 GO:0030641 regulation of cellular pH 4/580 81/18722 0.242491116264613 0.481154514397063 GRN/ATP6AP1/SLC9A1/ATP6AP2 4 GO:0044773 mitotic DNA damage checkpoint signaling 4/580 81/18722 0.242491116264613 0.481154514397063 SOX4/PPP1R10/PRKDC/CDK1 4 GO:0048144 fibroblast proliferation 4/580 81/18722 0.242491116264613 0.481154514397063 FTH1/PRKDC/CDK6/MIF 4 GO:1901988 negative regulation of cell cycle phase transition 10/580 249/18722 0.245074086789814 0.48607231456692 DUSP1/SOX4/ZFP36L1/PPP1R10/PRKDC/CENPF/EIF2AK4/TPR/CTDSPL/CDK1 10 GO:0043624 cellular protein complex disassembly 6/580 136/18722 0.246467357145911 0.4884191214681 SPTAN1/SPTBN1/CFL1/TRIOBP/HSPA8/STMN1 6 GO:0098876 vesicle-mediated transport to the plasma membrane 6/580 136/18722 0.246467357145911 0.4884191214681 GOLGA4/MACF1/SPTBN1/VAMP2/CMTM6/RAB11A 6 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 9/580 221/18722 0.247878604410601 0.491006554137012 UFL1/RPL23/HSPA1A/CTSC/TMEM259/HECTD1/CAV1/EIF3H/GPX1 9 GO:0006163 purine nucleotide metabolic process 15/580 396/18722 0.248339302543511 0.49126149172912 GAPDH/SLC26A2/LDHA/APP/ALDOA/ENO1/TPST2/ACSS1/HMGCR/TPI1/CROT/TMSB4X/PKM/RHOA/RAN 15 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 4/580 82/18722 0.24925161956368 0.49126149172912 PMAIP1/TIMP3/GPX1/HMGB2 4 GO:0002828 regulation of type 2 immune response 2/580 31/18722 0.249380430439143 0.49126149172912 CD81/PRKCZ 2 GO:0030149 sphingolipid catabolic process 2/580 31/18722 0.249380430439143 0.49126149172912 HEXA/NEU1 2 GO:0031063 regulation of histone deacetylation 2/580 31/18722 0.249380430439143 0.49126149172912 KDM5A/NIPBL 2 GO:0036474 cell death in response to hydrogen peroxide 2/580 31/18722 0.249380430439143 0.49126149172912 MET/TXN 2 GO:0044819 mitotic G1/S transition checkpoint signaling 2/580 31/18722 0.249380430439143 0.49126149172912 SOX4/PRKDC 2 GO:0048566 embryonic digestive tract development 2/580 31/18722 0.249380430439143 0.49126149172912 GLI3/NIPBL 2 GO:0060045 positive regulation of cardiac muscle cell proliferation 2/580 31/18722 0.249380430439143 0.49126149172912 TGFBR3/CDK1 2 GO:0060390 regulation of SMAD protein signal transduction 2/580 31/18722 0.249380430439143 0.49126149172912 LRP1/SPTBN1 2 GO:0070528 protein kinase C signaling 2/580 31/18722 0.249380430439143 0.49126149172912 ADGRG1/PRKCZ 2 GO:0070723 response to cholesterol 2/580 31/18722 0.249380430439143 0.49126149172912 DAG1/HMGCR 2 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 2/580 31/18722 0.249380430439143 0.49126149172912 GPX1/HMGB2 2 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 8/580 193/18722 0.250151728873347 0.492279754518058 IQGAP1/ISL1/ERBB3/CSH1/CD81/IL6ST/MIF/IGF2 8 GO:0002711 positive regulation of T cell mediated immunity 3/580 56/18722 0.250744084810423 0.492279754518058 CD81/CD55/PRKCZ 3 GO:0010518 positive regulation of phospholipase activity 3/580 56/18722 0.250744084810423 0.492279754518058 EGFR/GNAQ/PRKCZ 3 GO:0010658 striated muscle cell apoptotic process 3/580 56/18722 0.250744084810423 0.492279754518058 PPP1R10/HMGCR/BMP7 3 GO:0015800 acidic amino acid transport 3/580 56/18722 0.250744084810423 0.492279754518058 ITGB1/GJA1/ARL6IP5 3 GO:0042733 embryonic digit morphogenesis 3/580 56/18722 0.250744084810423 0.492279754518058 LRP5/GLI3/TBX3 3 GO:0046622 positive regulation of organ growth 3/580 56/18722 0.250744084810423 0.492279754518058 TGFBR3/IGF2/CDK1 3 GO:0048008 platelet-derived growth factor receptor signaling pathway 3/580 56/18722 0.250744084810423 0.492279754518058 LRP1/ARID5B/TXNIP 3 GO:0008203 cholesterol metabolic process 6/580 137/18722 0.251635377855937 0.493821157134162 APP/DHCR24/LRP5/HMGCR/POR/ACADVL 6 GO:0002285 lymphocyte activation involved in immune response 8/580 194/18722 0.254483335535942 0.499199491175735 RPS6/CD46/TFRC/CD81/EIF2AK4/XBP1/PRKCZ/HMGB1 8 GO:0002698 negative regulation of immune effector process 5/580 110/18722 0.255148714184632 0.499661755651673 GRN/CD46/PRKDC/CD55/SERPINB9 5 GO:0006939 smooth muscle contraction 5/580 110/18722 0.255148714184632 0.499661755651673 ATP2B1/ROCK1/TBX3/CAV1/RHOA 5 GO:0032611 interleukin-1 beta production 5/580 110/18722 0.255148714184632 0.499661755651673 EGR1/APP/ISL1/HMGB1/SERPINB1 5 GO:0032651 regulation of interleukin-1 beta production 5/580 110/18722 0.255148714184632 0.499661755651673 EGR1/APP/ISL1/HMGB1/SERPINB1 5 GO:0007249 I-kappaB kinase/NF-kappaB signaling 11/580 281/18722 0.256176504715972 0.499992549824028 GAPDH/UFL1/WLS/GJA1/ROCK1/HACD3/TFRC/BRD4/TMED4/NFKBIA/RHOA 11 GO:0048285 organelle fission 18/580 488/18722 0.256437244435875 0.499992549824028 DUSP1/HSPA1A/SLC2A8/LRP5/ATRX/PHIP/CENPF/NIPBL/BMP7/ASPM/TPR/RHOA/RAN/IGF2/CDC42/ANAPC11/RANBP1/RAB11A 18 GO:0006695 cholesterol biosynthetic process 3/580 57/18722 0.259124123165964 0.499992549824028 DHCR24/HMGCR/POR 3 GO:0006754 ATP biosynthetic process 3/580 57/18722 0.259124123165964 0.499992549824028 ALDOA/ENO1/TMSB4X 3 GO:0010883 regulation of lipid storage 3/580 57/18722 0.259124123165964 0.499992549824028 ITGAV/PLIN2/NFKBIA 3 GO:0034205 amyloid-beta formation 3/580 57/18722 0.259124123165964 0.499992549824028 NCSTN/ROCK1/RTN4 3 GO:0060042 retina morphogenesis in camera-type eye 3/580 57/18722 0.259124123165964 0.499992549824028 NAGLU/LRP5/TFAP2A 3 GO:0061005 cell differentiation involved in kidney development 3/580 57/18722 0.259124123165964 0.499992549824028 LGR4/IQGAP1/GLI3 3 GO:1902653 secondary alcohol biosynthetic process 3/580 57/18722 0.259124123165964 0.499992549824028 DHCR24/HMGCR/POR 3 GO:0009117 nucleotide metabolic process 18/580 489/18722 0.259162433044017 0.499992549824028 GAPDH/SLC26A2/LDHA/APP/ALDOA/ENO1/TPST2/ACSS1/HMGCR/TPI1/CROT/TMSB4X/PKM/DUT/TYMS/RHOA/RAN/RRM2 18 GO:0003338 metanephros morphogenesis 2/580 32/18722 0.260964059658914 0.499992549824028 FRAS1/LGR4 2 GO:0010743 regulation of macrophage derived foam cell differentiation 2/580 32/18722 0.260964059658914 0.499992549824028 ITGAV/NFKBIA 2 GO:0030431 sleep 2/580 32/18722 0.260964059658914 0.499992549824028 FOS/ADRB1 2 GO:0042744 hydrogen peroxide catabolic process 2/580 32/18722 0.260964059658914 0.499992549824028 GPX3/GPX1 2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity 2/580 32/18722 0.260964059658914 0.499992549824028 NR2F2/CDKN1C 2 GO:0045761 regulation of adenylate cyclase activity 2/580 32/18722 0.260964059658914 0.499992549824028 AKAP9/GNAI2 2 GO:0045879 negative regulation of smoothened signaling pathway 2/580 32/18722 0.260964059658914 0.499992549824028 GLI3/GPC3 2 GO:0048841 regulation of axon extension involved in axon guidance 2/580 32/18722 0.260964059658914 0.499992549824028 SEMA6A/SEMA6D 2 GO:0061036 positive regulation of cartilage development 2/580 32/18722 0.260964059658914 0.499992549824028 GLI3/POR 2 GO:0071875 adrenergic receptor signaling pathway 2/580 32/18722 0.260964059658914 0.499992549824028 ADRB1/GNAI2 2 GO:0090022 regulation of neutrophil chemotaxis 2/580 32/18722 0.260964059658914 0.499992549824028 DPP4/JAM3 2 GO:1901185 negative regulation of ERBB signaling pathway 2/580 32/18722 0.260964059658914 0.499992549824028 EGFR/LGMN 2 GO:1901532 regulation of hematopoietic progenitor cell differentiation 2/580 32/18722 0.260964059658914 0.499992549824028 N4BP2L2/PRKDC 2 GO:1901889 negative regulation of cell junction assembly 2/580 32/18722 0.260964059658914 0.499992549824028 LRP1/ROCK1 2 GO:1903955 positive regulation of protein targeting to mitochondrion 2/580 32/18722 0.260964059658914 0.499992549824028 LEPROT/UBE2L3 2 GO:1905476 negative regulation of protein localization to membrane 2/580 32/18722 0.260964059658914 0.499992549824028 HECTD1/TMEM59 2 GO:0090288 negative regulation of cellular response to growth factor stimulus 5/580 111/18722 0.26102355971885 0.499992549824028 FBN1/LRP2/SEMA6A/CRIM1/GPC1 5 GO:0055088 lipid homeostasis 7/580 167/18722 0.261036159443691 0.499992549824028 LRP5/RTN4/HMGCR/ORMDL1/CAV1/XBP1/MYLIP 7 GO:0045598 regulation of fat cell differentiation 6/580 139/18722 0.262060443038291 0.499992549824028 ZFP36L1/LRP5/DDIT3/BMP7/XBP1/ADIRF 6 GO:0097061 dendritic spine organization 4/580 84/18722 0.262889380985518 0.499992549824028 IGF1R/CFL1/LGMN/CDC42 4 GO:0006364 rRNA processing 9/580 225/18722 0.264083256408825 0.499992549824028 RPS21/RPS6/RPL7/RPS16/RPL14/RPS25/RPS17/PRKDC/FBL 9 GO:0002833 positive regulation of response to biotic stimulus 7/580 168/18722 0.265800572120205 0.499992549824028 GRN/CADM1/PRKDC/PUM1/HMGB1/HMGB2/CYBA 7 GO:1902806 regulation of cell cycle G1/S phase transition 7/580 168/18722 0.265800572120205 0.499992549824028 EGFR/SOX4/ADAMTS1/PRKDC/EIF4G1/CTDSPL/CCND3 7 GO:2000241 regulation of reproductive process 7/580 168/18722 0.265800572120205 0.499992549824028 SERPINF1/DUSP1/GJA1/CITED2/BMP7/ASPM/PHLDA2 7 GO:0001676 long-chain fatty acid metabolic process 5/580 112/18722 0.26692973281421 0.499992549824028 SLC27A2/PTGES2/CYP2J2/PTGES3/GPX1 5 GO:0046632 alpha-beta T cell differentiation 5/580 112/18722 0.26692973281421 0.499992549824028 CTSL/GLI3/PRKCZ/RHOA/HMGB1 5 GO:0002931 response to ischemia 3/580 58/18722 0.267540413865791 0.499992549824028 EGR1/GJA1/CAV1 3 GO:0006826 iron ion transport 3/580 58/18722 0.267540413865791 0.499992549824028 FTH1/TFRC/SLC40A1 3 GO:0032481 positive regulation of type I interferon production 3/580 58/18722 0.267540413865791 0.499992549824028 GAPDH/HMGB1/HMGB2 3 GO:2000736 regulation of stem cell differentiation 3/580 58/18722 0.267540413865791 0.499992549824028 N4BP2L2/PRKDC/TACSTD2 3 GO:0002709 regulation of T cell mediated immunity 4/580 85/18722 0.269760856185646 0.499992549824028 CD81/CD55/PRKCZ/HMGB1 4 GO:0009142 nucleoside triphosphate biosynthetic process 4/580 85/18722 0.269760856185646 0.499992549824028 ALDOA/ENO1/TMSB4X/TYMS 4 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 4/580 85/18722 0.269760856185646 0.499992549824028 ISL1/CSH1/CAV1/IL6ST 4 GO:0044774 mitotic DNA integrity checkpoint signaling 4/580 85/18722 0.269760856185646 0.499992549824028 SOX4/PPP1R10/PRKDC/CDK1 4 GO:0055013 cardiac muscle cell development 4/580 85/18722 0.269760856185646 0.499992549824028 PLEC/ISL1/TBX3/CDK1 4 GO:0055072 iron ion homeostasis 4/580 85/18722 0.269760856185646 0.499992549824028 FTH1/ATP6AP1/TFRC/SLC40A1 4 GO:0001820 serotonin secretion 1/580 10/18722 0.270045427898938 0.499992549824028 SLC6A4 1 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 1/580 10/18722 0.270045427898938 0.499992549824028 CD81 1 GO:0003183 mitral valve morphogenesis 1/580 10/18722 0.270045427898938 0.499992549824028 SOX4 1 GO:0005984 disaccharide metabolic process 1/580 10/18722 0.270045427898938 0.499992549824028 GAA 1 GO:0006646 phosphatidylethanolamine biosynthetic process 1/580 10/18722 0.270045427898938 0.499992549824028 PISD 1 GO:0006735 NADH regeneration 1/580 10/18722 0.270045427898938 0.499992549824028 ENO1 1 GO:0007028 cytoplasm organization 1/580 10/18722 0.270045427898938 0.499992549824028 KIF5B 1 GO:0009750 response to fructose 1/580 10/18722 0.270045427898938 0.499992549824028 XBP1 1 GO:0010172 embryonic body morphogenesis 1/580 10/18722 0.270045427898938 0.499992549824028 DAG1 1 GO:0010944 negative regulation of transcription by competitive promoter binding 1/580 10/18722 0.270045427898938 0.499992549824028 TFAP2A 1 GO:0010968 regulation of microtubule nucleation 1/580 10/18722 0.270045427898938 0.499992549824028 HSPA1A 1 GO:0015808 L-alanine transport 1/580 10/18722 0.270045427898938 0.499992549824028 SLC3A2 1 GO:0015911 long-chain fatty acid import across plasma membrane 1/580 10/18722 0.270045427898938 0.499992549824028 SLC2A1 1 GO:0017085 response to insecticide 1/580 10/18722 0.270045427898938 0.499992549824028 UBA52 1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 1/580 10/18722 0.270045427898938 0.499992549824028 P4HB 1 GO:0019062 virion attachment to host cell 1/580 10/18722 0.270045427898938 0.499992549824028 CD81 1 GO:0019532 oxalate transport 1/580 10/18722 0.270045427898938 0.499992549824028 SLC26A2 1 GO:0021562 vestibulocochlear nerve development 1/580 10/18722 0.270045427898938 0.499992549824028 NRP2 1 GO:0021903 rostrocaudal neural tube patterning 1/580 10/18722 0.270045427898938 0.499992549824028 ATP6AP2 1 GO:0021932 hindbrain radial glia guided cell migration 1/580 10/18722 0.270045427898938 0.499992549824028 ITGB1 1 GO:0030388 fructose 1,6-bisphosphate metabolic process 1/580 10/18722 0.270045427898938 0.499992549824028 ALDOA 1 GO:0030953 astral microtubule organization 1/580 10/18722 0.270045427898938 0.499992549824028 RAB11A 1 GO:0031125 rRNA 3'-end processing 1/580 10/18722 0.270045427898938 0.499992549824028 RPS21 1 GO:0031340 positive regulation of vesicle fusion 1/580 10/18722 0.270045427898938 0.499992549824028 KIF5B 1 GO:0031642 negative regulation of myelination 1/580 10/18722 0.270045427898938 0.499992549824028 CTSC 1 GO:0032025 response to cobalt ion 1/580 10/18722 0.270045427898938 0.499992549824028 SERPINF1 1 GO:0032253 dense core granule localization 1/580 10/18722 0.270045427898938 0.499992549824028 KIF5B 1 GO:0032275 luteinizing hormone secretion 1/580 10/18722 0.270045427898938 0.499992549824028 TBX3 1 GO:0033572 transferrin transport 1/580 10/18722 0.270045427898938 0.499992549824028 TFRC 1 GO:0034085 establishment of sister chromatid cohesion 1/580 10/18722 0.270045427898938 0.499992549824028 NIPBL 1 GO:0035376 sterol import 1/580 10/18722 0.270045427898938 0.499992549824028 LRP1 1 GO:0035999 tetrahydrofolate interconversion 1/580 10/18722 0.270045427898938 0.499992549824028 TYMS 1 GO:0042989 sequestering of actin monomers 1/580 10/18722 0.270045427898938 0.499992549824028 TMSB4X 1 GO:0044848 biological phase 1/580 10/18722 0.270045427898938 0.499992549824028 FERMT1 1 GO:0045348 positive regulation of MHC class II biosynthetic process 1/580 10/18722 0.270045427898938 0.499992549824028 XBP1 1 GO:0045792 negative regulation of cell size 1/580 10/18722 0.270045427898938 0.499992549824028 RHOA 1 GO:0045898 regulation of RNA polymerase II transcription preinitiation complex assembly 1/580 10/18722 0.270045427898938 0.499992549824028 HMGB1 1 GO:0048194 Golgi vesicle budding 1/580 10/18722 0.270045427898938 0.499992549824028 TMED9 1 GO:0048262 determination of dorsal/ventral asymmetry 1/580 10/18722 0.270045427898938 0.499992549824028 DDIT3 1 GO:0048672 positive regulation of collateral sprouting 1/580 10/18722 0.270045427898938 0.499992549824028 LRP1 1 GO:0048703 embryonic viscerocranium morphogenesis 1/580 10/18722 0.270045427898938 0.499992549824028 NIPBL 1 GO:0048755 branching morphogenesis of a nerve 1/580 10/18722 0.270045427898938 0.499992549824028 RTN4 1 GO:0051351 positive regulation of ligase activity 1/580 10/18722 0.270045427898938 0.499992549824028 TMSB4X 1 GO:0060068 vagina development 1/580 10/18722 0.270045427898938 0.499992549824028 LRP2 1 GO:0060272 embryonic skeletal joint morphogenesis 1/580 10/18722 0.270045427898938 0.499992549824028 BMP7 1 GO:0060513 prostatic bud formation 1/580 10/18722 0.270045427898938 0.499992549824028 BMP7 1 GO:0060736 prostate gland growth 1/580 10/18722 0.270045427898938 0.499992549824028 PSAP 1 GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 1/580 10/18722 0.270045427898938 0.499992549824028 SERPINF1 1 GO:0060923 cardiac muscle cell fate commitment 1/580 10/18722 0.270045427898938 0.499992549824028 TBX3 1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus 1/580 10/18722 0.270045427898938 0.499992549824028 HMGCR 1 GO:0061299 retina vasculature morphogenesis in camera-type eye 1/580 10/18722 0.270045427898938 0.499992549824028 LRP5 1 GO:0061621 canonical glycolysis 1/580 10/18722 0.270045427898938 0.499992549824028 ENO1 1 GO:0061718 glucose catabolic process to pyruvate 1/580 10/18722 0.270045427898938 0.499992549824028 ENO1 1 GO:0070508 cholesterol import 1/580 10/18722 0.270045427898938 0.499992549824028 LRP1 1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum 1/580 10/18722 0.270045427898938 0.499992549824028 OS9 1 GO:0071372 cellular response to follicle-stimulating hormone stimulus 1/580 10/18722 0.270045427898938 0.499992549824028 POR 1 GO:0071803 positive regulation of podosome assembly 1/580 10/18722 0.270045427898938 0.499992549824028 RHOA 1 GO:0072070 loop of Henle development 1/580 10/18722 0.270045427898938 0.499992549824028 IRX2 1 GO:0072178 nephric duct morphogenesis 1/580 10/18722 0.270045427898938 0.499992549824028 GPC3 1 GO:0072378 blood coagulation, fibrin clot formation 1/580 10/18722 0.270045427898938 0.499992549824028 FBLN1 1 GO:0090647 modulation of age-related behavioral decline 1/580 10/18722 0.270045427898938 0.499992549824028 APP 1 GO:0097084 vascular associated smooth muscle cell development 1/580 10/18722 0.270045427898938 0.499992549824028 ADM 1 GO:0097278 complement-dependent cytotoxicity 1/580 10/18722 0.270045427898938 0.499992549824028 CD55 1 GO:0098903 regulation of membrane repolarization during action potential 1/580 10/18722 0.270045427898938 0.499992549824028 CAV1 1 GO:0098917 retrograde trans-synaptic signaling 1/580 10/18722 0.270045427898938 0.499992549824028 DAG1 1 GO:0099519 dense core granule cytoskeletal transport 1/580 10/18722 0.270045427898938 0.499992549824028 KIF5B 1 GO:0099639 neurotransmitter receptor transport, endosome to plasma membrane 1/580 10/18722 0.270045427898938 0.499992549824028 RAB11A 1 GO:0140059 dendrite arborization 1/580 10/18722 0.270045427898938 0.499992549824028 TPBG 1 GO:1900246 positive regulation of RIG-I signaling pathway 1/580 10/18722 0.270045427898938 0.499992549824028 PUM1 1 GO:1901203 positive regulation of extracellular matrix assembly 1/580 10/18722 0.270045427898938 0.499992549824028 DAG1 1 GO:1901524 regulation of mitophagy 1/580 10/18722 0.270045427898938 0.499992549824028 VDAC1 1 GO:1901725 regulation of histone deacetylase activity 1/580 10/18722 0.270045427898938 0.499992549824028 KDM5A 1 GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 1/580 10/18722 0.270045427898938 0.499992549824028 NCL 1 GO:1901950 dense core granule transport 1/580 10/18722 0.270045427898938 0.499992549824028 KIF5B 1 GO:1901978 positive regulation of cell cycle checkpoint 1/580 10/18722 0.270045427898938 0.499992549824028 TPR 1 GO:1902023 L-arginine transport 1/580 10/18722 0.270045427898938 0.499992549824028 SLC38A9 1 GO:1903826 arginine transmembrane transport 1/580 10/18722 0.270045427898938 0.499992549824028 SLC38A9 1 GO:1903867 extraembryonic membrane development 1/580 10/18722 0.270045427898938 0.499992549824028 BMP7 1 GO:1903980 positive regulation of microglial cell activation 1/580 10/18722 0.270045427898938 0.499992549824028 CTSC 1 GO:1905383 protein localization to presynapse 1/580 10/18722 0.270045427898938 0.499992549824028 KIF5B 1 GO:1905941 positive regulation of gonad development 1/580 10/18722 0.270045427898938 0.499992549824028 CITED2 1 GO:1990253 cellular response to leucine starvation 1/580 10/18722 0.270045427898938 0.499992549824028 EIF2AK4 1 GO:1990535 neuron projection maintenance 1/580 10/18722 0.270045427898938 0.499992549824028 APP 1 GO:2000018 regulation of male gonad development 1/580 10/18722 0.270045427898938 0.499992549824028 CITED2 1 GO:2000121 regulation of removal of superoxide radicals 1/580 10/18722 0.270045427898938 0.499992549824028 BMP7 1 GO:2000169 regulation of peptidyl-cysteine S-nitrosylation 1/580 10/18722 0.270045427898938 0.499992549824028 TXN 1 GO:2000288 positive regulation of myoblast proliferation 1/580 10/18722 0.270045427898938 0.499992549824028 MALAT1 1 GO:2000425 regulation of apoptotic cell clearance 1/580 10/18722 0.270045427898938 0.499992549824028 HMGB1 1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation 1/580 10/18722 0.270045427898938 0.499992549824028 WASF2 1 GO:2001223 negative regulation of neuron migration 1/580 10/18722 0.270045427898938 0.499992549824028 ADGRG1 1 GO:2001225 regulation of chloride transport 1/580 10/18722 0.270045427898938 0.499992549824028 GABRE 1 GO:0048167 regulation of synaptic plasticity 8/580 198/18722 0.272036667356364 0.500925640778344 APP/NCSTN/EIF2AK4/VAMP2/LGMN/PRKCZ/YWHAH/RAB11A 8 GO:0046777 protein autophosphorylation 9/580 227/18722 0.272306891985326 0.500925640778344 EGFR/AAK1/IQGAP1/EPHB4/IGF1R/CALM1/EIF2AK4/CAV1/CALM2 9 GO:0001975 response to amphetamine 2/580 33/18722 0.272551567482163 0.500925640778344 CALM1/RGS10 2 GO:0006891 intra-Golgi vesicle-mediated transport 2/580 33/18722 0.272551567482163 0.500925640778344 COPA/CUX1 2 GO:0032633 interleukin-4 production 2/580 33/18722 0.272551567482163 0.500925640778344 DDIT3/PRKCZ 2 GO:0032673 regulation of interleukin-4 production 2/580 33/18722 0.272551567482163 0.500925640778344 DDIT3/PRKCZ 2 GO:0036336 dendritic cell migration 2/580 33/18722 0.272551567482163 0.500925640778344 HMGB1/CDC42 2 GO:0050901 leukocyte tethering or rolling 2/580 33/18722 0.272551567482163 0.500925640778344 ITGB1/ROCK1 2 GO:0060122 inner ear receptor cell stereocilium organization 2/580 33/18722 0.272551567482163 0.500925640778344 TRIP11/TRIOBP 2 GO:0071295 cellular response to vitamin 2/580 33/18722 0.272551567482163 0.500925640778344 ATP2B1/FOLR1 2 GO:0099174 regulation of presynapse organization 2/580 33/18722 0.272551567482163 0.500925640778344 APP/EIF4G1 2 GO:0120033 negative regulation of plasma membrane bounded cell projection assembly 2/580 33/18722 0.272551567482163 0.500925640778344 KANK1/TACSTD2 2 GO:0150117 positive regulation of cell-substrate junction organization 2/580 33/18722 0.272551567482163 0.500925640778344 IQGAP1/ROCK1 2 GO:1902275 regulation of chromatin organization 2/580 33/18722 0.272551567482163 0.500925640778344 TPR/MPHOSPH8 2 GO:1902692 regulation of neuroblast proliferation 2/580 33/18722 0.272551567482163 0.500925640778344 GLI3/ASPM 2 GO:1902992 negative regulation of amyloid precursor protein catabolic process 2/580 33/18722 0.272551567482163 0.500925640778344 ROCK1/RTN4 2 GO:1904030 negative regulation of cyclin-dependent protein kinase activity 2/580 33/18722 0.272551567482163 0.500925640778344 NR2F2/CDKN1C 2 GO:1905606 regulation of presynapse assembly 2/580 33/18722 0.272551567482163 0.500925640778344 APP/EIF4G1 2 GO:0006119 oxidative phosphorylation 6/580 141/18722 0.272595742165124 0.500925640778344 COX6A1/NDUFB9/RHOA/UQCRH/COX8C/CDK1 6 GO:0002708 positive regulation of lymphocyte mediated immunity 5/580 113/18722 0.272865409152491 0.501223150856333 CADM1/TFRC/CD81/CD55/PRKCZ 5 GO:0007259 receptor signaling pathway via JAK-STAT 7/580 170/18722 0.275400069257935 0.505679321799707 ISL1/IL10RB/CSH1/PRLR/CAV1/IL6ST/LEPROT 7 GO:0001836 release of cytochrome c from mitochondria 3/580 59/18722 0.275987803123081 0.506558513151322 JUN/PMAIP1/GPX1 3 GO:0015908 fatty acid transport 4/580 86/18722 0.276663585515778 0.507198398200191 SLC2A1/SLC27A2/CROT/PLIN2 4 GO:0034103 regulation of tissue remodeling 4/580 86/18722 0.276663585515778 0.507198398200191 EGFR/ATP6AP1/ROCK1/TFRC 4 GO:1903510 mucopolysaccharide metabolic process 4/580 86/18722 0.276663585515778 0.507198398200191 ITIH5/CHPF/CHST12/GNS 4 GO:0097553 calcium ion transmembrane import into cytosol 6/580 142/18722 0.277901551696824 0.509267185556316 DDIT3/DIAPH1/CALM1/GSTO1/CALM2/CYBA 6 GO:1904892 regulation of receptor signaling pathway via STAT 5/580 114/18722 0.278828771331762 0.510765110462396 IL10RB/CSH1/PRLR/CAV1/LEPROT 5 GO:0010506 regulation of autophagy 12/580 317/18722 0.279738173164637 0.512229229680601 GAPDH/EEF1A1/UFL1/MET/PSAP/CTSA/DDIT3/ROCK1/EIF4G1/TMEM59/HMGB1/VDAC1 12 GO:0006753 nucleoside phosphate metabolic process 18/580 497/18722 0.281350839218642 0.512698230497608 GAPDH/SLC26A2/LDHA/APP/ALDOA/ENO1/TPST2/ACSS1/HMGCR/TPI1/CROT/TMSB4X/PKM/DUT/TYMS/RHOA/RAN/RRM2 18 GO:0001776 leukocyte homeostasis 4/580 87/18722 0.283594750669885 0.512698230497608 RPS6/PMAIP1/JAM3/HMGB1 4 GO:0019646 aerobic electron transport chain 4/580 87/18722 0.283594750669885 0.512698230497608 COX6A1/NDUFB9/UQCRH/COX8C 4 GO:0019915 lipid storage 4/580 87/18722 0.283594750669885 0.512698230497608 ITGAV/CAV1/PLIN2/NFKBIA 4 GO:1903578 regulation of ATP metabolic process 4/580 87/18722 0.283594750669885 0.512698230497608 APP/ENO1/TMSB4X/RHOA 4 GO:0000038 very long-chain fatty acid metabolic process 2/580 34/18722 0.284131615719373 0.512698230497608 SLC27A2/HACD3 2 GO:0007616 long-term memory 2/580 34/18722 0.284131615719373 0.512698230497608 EIF2AK4/PRKCZ 2 GO:0009649 entrainment of circadian clock 2/580 34/18722 0.284131615719373 0.512698230497608 GNAQ/NR2F6 2 GO:0019076 viral release from host cell 2/580 34/18722 0.284131615719373 0.512698230497608 DDB1/PPIA 2 GO:0019320 hexose catabolic process 2/580 34/18722 0.284131615719373 0.512698230497608 ENO1/LRP5 2 GO:0032770 positive regulation of monooxygenase activity 2/580 34/18722 0.284131615719373 0.512698230497608 CALM1/POR 2 GO:0034383 low-density lipoprotein particle clearance 2/580 34/18722 0.284131615719373 0.512698230497608 CNPY2/MYLIP 2 GO:0035137 hindlimb morphogenesis 2/580 34/18722 0.284131615719373 0.512698230497608 TBX3/GPC3 2 GO:0035890 exit from host 2/580 34/18722 0.284131615719373 0.512698230497608 DDB1/PPIA 2 GO:0035891 exit from host cell 2/580 34/18722 0.284131615719373 0.512698230497608 DDB1/PPIA 2 GO:0035909 aorta morphogenesis 2/580 34/18722 0.284131615719373 0.512698230497608 LRP1/SOX4 2 GO:0043276 anoikis 2/580 34/18722 0.284131615719373 0.512698230497608 ITGB1/CAV1 2 GO:0044319 wound healing, spreading of cells 2/580 34/18722 0.284131615719373 0.512698230497608 FERMT1/RHOA 2 GO:0048261 negative regulation of receptor-mediated endocytosis 2/580 34/18722 0.284131615719373 0.512698230497608 ITGAV/LRPAP1 2 GO:0048741 skeletal muscle fiber development 2/580 34/18722 0.284131615719373 0.512698230497608 PLEC/GPX1 2 GO:0055094 response to lipoprotein particle 2/580 34/18722 0.284131615719373 0.512698230497608 ITGB1/CD81 2 GO:0070884 regulation of calcineurin-NFAT signaling cascade 2/580 34/18722 0.284131615719373 0.512698230497608 NFAT5/SLC9A1 2 GO:0086019 cell-cell signaling involved in cardiac conduction 2/580 34/18722 0.284131615719373 0.512698230497608 GJA5/GJA1 2 GO:0090505 epiboly involved in wound healing 2/580 34/18722 0.284131615719373 0.512698230497608 FERMT1/RHOA 2 GO:1904893 negative regulation of receptor signaling pathway via STAT 2/580 34/18722 0.284131615719373 0.512698230497608 CAV1/LEPROT 2 GO:2000758 positive regulation of peptidyl-lysine acetylation 2/580 34/18722 0.284131615719373 0.512698230497608 SOX4/ISL1 2 GO:0002712 regulation of B cell mediated immunity 3/580 60/18722 0.284461262143071 0.512698230497608 CD46/TFRC/CD55 3 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 3/580 60/18722 0.284461262143071 0.512698230497608 HSPA1A/PUM1/NFKBIA 3 GO:0002889 regulation of immunoglobulin mediated immune response 3/580 60/18722 0.284461262143071 0.512698230497608 CD46/TFRC/CD55 3 GO:1903670 regulation of sprouting angiogenesis 3/580 60/18722 0.284461262143071 0.512698230497608 SEMA6A/PKM/HMGB1 3 GO:0000077 DNA damage checkpoint signaling 5/580 115/18722 0.284818010251672 0.512698230497608 SOX4/PPP1R10/PRKDC/EIF2AK4/CDK1 5 GO:0071675 regulation of mononuclear cell migration 5/580 115/18722 0.284818010251672 0.512698230497608 APP/DUSP1/LGMN/RHOA/HMGB1 5 GO:0010821 regulation of mitochondrion organization 6/580 144/18722 0.288583139067312 0.512698230497608 HSPA1A/TFRC/PMAIP1/PISD/GPX1/VDAC1 6 GO:0031644 regulation of nervous system process 6/580 144/18722 0.288583139067312 0.512698230497608 AKAP9/DAG1/APP/CTSC/SLC9A1/PRKCZ 6 GO:0000819 sister chromatid segregation 8/580 202/18722 0.289918061612543 0.512698230497608 DUSP1/ATRX/CENPF/NIPBL/TPR/RAN/ANAPC11/RAB11A 8 GO:0009913 epidermal cell differentiation 8/580 202/18722 0.289918061612543 0.512698230497608 PLEC/ZFP36L1/ROCK1/TRIOBP/DSP/NCOA3/SRSF6/TXNIP 8 GO:0007260 tyrosine phosphorylation of STAT protein 4/580 88/18722 0.29055156663451 0.512698230497608 ISL1/CSH1/CAV1/IL6ST 4 GO:0007006 mitochondrial membrane organization 5/580 116/18722 0.290831326446941 0.512698230497608 HSPA1A/SLC9A1/CALM1/PMAIP1/DYNLT1 5 GO:0030518 intracellular steroid hormone receptor signaling pathway 5/580 116/18722 0.290831326446941 0.512698230497608 UFL1/ISL1/PTGES3/RHOA/YWHAH 5 GO:0001765 membrane raft assembly 1/580 11/18722 0.292671210916179 0.512698230497608 CAV1 1 GO:0001967 suckling behavior 1/580 11/18722 0.292671210916179 0.512698230497608 APP 1 GO:0003263 cardioblast proliferation 1/580 11/18722 0.292671210916179 0.512698230497608 ISL1 1 GO:0003264 regulation of cardioblast proliferation 1/580 11/18722 0.292671210916179 0.512698230497608 ISL1 1 GO:0006020 inositol metabolic process 1/580 11/18722 0.292671210916179 0.512698230497608 ISYNA1 1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 1/580 11/18722 0.292671210916179 0.512698230497608 UQCRH 1 GO:0010269 response to selenium ion 1/580 11/18722 0.292671210916179 0.512698230497608 GPX1 1 GO:0010739 positive regulation of protein kinase A signaling 1/580 11/18722 0.292671210916179 0.512698230497608 MIF 1 GO:0014854 response to inactivity 1/580 11/18722 0.292671210916179 0.512698230497608 DAG1 1 GO:0019048 modulation by virus of host process 1/580 11/18722 0.292671210916179 0.512698230497608 DAG1 1 GO:0021561 facial nerve development 1/580 11/18722 0.292671210916179 0.512698230497608 NRP2 1 GO:0021604 cranial nerve structural organization 1/580 11/18722 0.292671210916179 0.512698230497608 NRP2 1 GO:0021610 facial nerve morphogenesis 1/580 11/18722 0.292671210916179 0.512698230497608 NRP2 1 GO:0030432 peristalsis 1/580 11/18722 0.292671210916179 0.512698230497608 TBX3 1 GO:0032276 regulation of gonadotropin secretion 1/580 11/18722 0.292671210916179 0.512698230497608 GJA1 1 GO:0032610 interleukin-1 alpha production 1/580 11/18722 0.292671210916179 0.512698230497608 ISL1 1 GO:0032650 regulation of interleukin-1 alpha production 1/580 11/18722 0.292671210916179 0.512698230497608 ISL1 1 GO:0033327 Leydig cell differentiation 1/580 11/18722 0.292671210916179 0.512698230497608 SF1 1 GO:0033483 gas homeostasis 1/580 11/18722 0.292671210916179 0.512698230497608 CAV1 1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase 1/580 11/18722 0.292671210916179 0.512698230497608 ACADVL 1 GO:0033625 positive regulation of integrin activation 1/580 11/18722 0.292671210916179 0.512698230497608 FERMT1 1 GO:0033632 regulation of cell-cell adhesion mediated by integrin 1/580 11/18722 0.292671210916179 0.512698230497608 DPP4 1 GO:0034770 histone H4-K20 methylation 1/580 11/18722 0.292671210916179 0.512698230497608 NSD1 1 GO:0034776 response to histamine 1/580 11/18722 0.292671210916179 0.512698230497608 DIAPH1 1 GO:0035457 cellular response to interferon-alpha 1/580 11/18722 0.292671210916179 0.512698230497608 TPR 1 GO:0044068 modulation by symbiont of host cellular process 1/580 11/18722 0.292671210916179 0.512698230497608 SERPINB9 1 GO:0045060 negative thymic T cell selection 1/580 11/18722 0.292671210916179 0.512698230497608 GLI3 1 GO:0045628 regulation of T-helper 2 cell differentiation 1/580 11/18722 0.292671210916179 0.512698230497608 PRKCZ 1 GO:0045654 positive regulation of megakaryocyte differentiation 1/580 11/18722 0.292671210916179 0.512698230497608 HMGB2 1 GO:0046598 positive regulation of viral entry into host cell 1/580 11/18722 0.292671210916179 0.512698230497608 P4HB 1 GO:0046643 regulation of gamma-delta T cell activation 1/580 11/18722 0.292671210916179 0.512698230497608 SOX4 1 GO:0048096 chromatin-mediated maintenance of transcription 1/580 11/18722 0.292671210916179 0.512698230497608 SERTAD1 1 GO:0048102 autophagic cell death 1/580 11/18722 0.292671210916179 0.512698230497608 CTSV 1 GO:0051610 serotonin uptake 1/580 11/18722 0.292671210916179 0.512698230497608 SLC6A4 1 GO:0055015 ventricular cardiac muscle cell development 1/580 11/18722 0.292671210916179 0.512698230497608 CDK1 1 GO:0060174 limb bud formation 1/580 11/18722 0.292671210916179 0.512698230497608 SOX4 1 GO:0060379 cardiac muscle cell myoblast differentiation 1/580 11/18722 0.292671210916179 0.512698230497608 ISL1 1 GO:0060579 ventral spinal cord interneuron fate commitment 1/580 11/18722 0.292671210916179 0.512698230497608 GLI3 1 GO:0060581 cell fate commitment involved in pattern specification 1/580 11/18722 0.292671210916179 0.512698230497608 GLI3 1 GO:0060742 epithelial cell differentiation involved in prostate gland development 1/580 11/18722 0.292671210916179 0.512698230497608 PSAP 1 GO:0060767 epithelial cell proliferation involved in prostate gland development 1/580 11/18722 0.292671210916179 0.512698230497608 SERPINF1 1 GO:0060900 embryonic camera-type eye formation 1/580 11/18722 0.292671210916179 0.512698230497608 TFAP2A 1 GO:0061029 eyelid development in camera-type eye 1/580 11/18722 0.292671210916179 0.512698230497608 TFAP2A 1 GO:0061314 Notch signaling involved in heart development 1/580 11/18722 0.292671210916179 0.512698230497608 GALNT11 1 GO:0061635 regulation of protein complex stability 1/580 11/18722 0.292671210916179 0.512698230497608 HSPA8 1 GO:0070778 L-aspartate transmembrane transport 1/580 11/18722 0.292671210916179 0.512698230497608 SLC1A5 1 GO:0071679 commissural neuron axon guidance 1/580 11/18722 0.292671210916179 0.512698230497608 DAG1 1 GO:0071888 macrophage apoptotic process 1/580 11/18722 0.292671210916179 0.512698230497608 CTSL 1 GO:0072173 metanephric tubule morphogenesis 1/580 11/18722 0.292671210916179 0.512698230497608 LGR4 1 GO:0072205 metanephric collecting duct development 1/580 11/18722 0.292671210916179 0.512698230497608 DLG5 1 GO:0075294 positive regulation by symbiont of entry into host 1/580 11/18722 0.292671210916179 0.512698230497608 P4HB 1 GO:0075522 IRES-dependent viral translational initiation 1/580 11/18722 0.292671210916179 0.512698230497608 EIF3A 1 GO:0075733 intracellular transport of virus 1/580 11/18722 0.292671210916179 0.512698230497608 DYNLT1 1 GO:0086016 AV node cell action potential 1/580 11/18722 0.292671210916179 0.512698230497608 GJA5 1 GO:0086027 AV node cell to bundle of His cell signaling 1/580 11/18722 0.292671210916179 0.512698230497608 GJA5 1 GO:0086070 SA node cell to atrial cardiac muscle cell communication 1/580 11/18722 0.292671210916179 0.512698230497608 GJA5 1 GO:0090030 regulation of steroid hormone biosynthetic process 1/580 11/18722 0.292671210916179 0.512698230497608 POR 1 GO:0090205 positive regulation of cholesterol metabolic process 1/580 11/18722 0.292671210916179 0.512698230497608 POR 1 GO:0090309 positive regulation of DNA methylation-dependent heterochromatin assembly 1/580 11/18722 0.292671210916179 0.512698230497608 MPHOSPH8 1 GO:0097494 regulation of vesicle size 1/580 11/18722 0.292671210916179 0.512698230497608 RAB11A 1 GO:0099022 vesicle tethering 1/580 11/18722 0.292671210916179 0.512698230497608 TRIP11 1 GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 1/580 11/18722 0.292671210916179 0.512698230497608 GNAI2 1 GO:1900112 regulation of histone H3-K9 trimethylation 1/580 11/18722 0.292671210916179 0.512698230497608 ATRX 1 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation 1/580 11/18722 0.292671210916179 0.512698230497608 N4BP2L2 1 GO:1902033 regulation of hematopoietic stem cell proliferation 1/580 11/18722 0.292671210916179 0.512698230497608 N4BP2L2 1 GO:1902188 positive regulation of viral release from host cell 1/580 11/18722 0.292671210916179 0.512698230497608 DDB1 1 GO:1902337 regulation of apoptotic process involved in morphogenesis 1/580 11/18722 0.292671210916179 0.512698230497608 BMP7 1 GO:1902667 regulation of axon guidance 1/580 11/18722 0.292671210916179 0.512698230497608 MYCBP2 1 GO:1902915 negative regulation of protein polyubiquitination 1/580 11/18722 0.292671210916179 0.512698230497608 PPIA 1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway 1/580 11/18722 0.292671210916179 0.512698230497608 HSPA1A 1 GO:1905050 positive regulation of metallopeptidase activity 1/580 11/18722 0.292671210916179 0.512698230497608 CLDN4 1 GO:1905150 regulation of voltage-gated sodium channel activity 1/580 11/18722 0.292671210916179 0.512698230497608 KIF5B 1 GO:1905522 negative regulation of macrophage migration 1/580 11/18722 0.292671210916179 0.512698230497608 MIF 1 GO:2000392 regulation of lamellipodium morphogenesis 1/580 11/18722 0.292671210916179 0.512698230497608 KANK1 1 GO:2000644 regulation of receptor catabolic process 1/580 11/18722 0.292671210916179 0.512698230497608 MYLIP 1 GO:2001053 regulation of mesenchymal cell apoptotic process 1/580 11/18722 0.292671210916179 0.512698230497608 BMP7 1 GO:1904356 regulation of telomere maintenance via telomere lengthening 3/580 61/18722 0.292955889232038 0.513003705127338 HNRNPA1/HNRNPC/HNRNPA2B1 3 GO:0000460 maturation of 5.8S rRNA 2/580 35/18722 0.295693562620283 0.514312176419946 RPS21/PRKDC 2 GO:0006298 mismatch repair 2/580 35/18722 0.295693562620283 0.514312176419946 HMGB1/PCNA 2 GO:0007020 microtubule nucleation 2/580 35/18722 0.295693562620283 0.514312176419946 AKAP9/HSPA1A 2 GO:0010837 regulation of keratinocyte proliferation 2/580 35/18722 0.295693562620283 0.514312176419946 ZFP36L1/SRSF6 2 GO:0032205 negative regulation of telomere maintenance 2/580 35/18722 0.295693562620283 0.514312176419946 HNRNPA1/HNRNPC 2 GO:0033146 regulation of intracellular estrogen receptor signaling pathway 2/580 35/18722 0.295693562620283 0.514312176419946 UFL1/ISL1 2 GO:0033280 response to vitamin D 2/580 35/18722 0.295693562620283 0.514312176419946 ATP2B1/BMP7 2 GO:0039694 viral RNA genome replication 2/580 35/18722 0.295693562620283 0.514312176419946 MPHOSPH8/CDC42 2 GO:0042462 eye photoreceptor cell development 2/580 35/18722 0.295693562620283 0.514312176419946 NAGLU/TUG1 2 GO:0046627 negative regulation of insulin receptor signaling pathway 2/580 35/18722 0.295693562620283 0.514312176419946 KANK1/PRKCZ 2 GO:0046640 regulation of alpha-beta T cell proliferation 2/580 35/18722 0.295693562620283 0.514312176419946 CD81/CD55 2 GO:0048821 erythrocyte development 2/580 35/18722 0.295693562620283 0.514312176419946 RPS6/CITED2 2 GO:0072528 pyrimidine-containing compound biosynthetic process 2/580 35/18722 0.295693562620283 0.514312176419946 DUT/TYMS 2 GO:0090181 regulation of cholesterol metabolic process 2/580 35/18722 0.295693562620283 0.514312176419946 POR/ACADVL 2 GO:0090504 epiboly 2/580 35/18722 0.295693562620283 0.514312176419946 FERMT1/RHOA 2 GO:0098810 neurotransmitter reuptake 2/580 35/18722 0.295693562620283 0.514312176419946 ITGB1/SLC6A4 2 GO:0106056 regulation of calcineurin-mediated signaling 2/580 35/18722 0.295693562620283 0.514312176419946 NFAT5/SLC9A1 2 GO:2000403 positive regulation of lymphocyte migration 2/580 35/18722 0.295693562620283 0.514312176419946 APP/RHOA 2 GO:0002702 positive regulation of production of molecular mediator of immune response 5/580 117/18722 0.296866931369298 0.515967151643723 TFRC/CD81/XBP1/CD55/PRKCZ 5 GO:0014902 myotube differentiation 5/580 117/18722 0.296866931369298 0.515967151643723 PLEC/CD81/PLD3/XBP1/GPX1 5 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 9/580 233/18722 0.297406818705454 0.516712407097149 ADGRG1/LGR5/LGR4/PSAP/ADRB1/ADM/GNAQ/WASF2/GNAI2 9 GO:0010675 regulation of cellular carbohydrate metabolic process 6/580 146/18722 0.299349571596113 0.519893524082718 DDB1/PMAIP1/PHLDA2/PGP/HMGB1/IGF2 6 GO:0010573 vascular endothelial growth factor production 3/580 62/18722 0.301466911506256 0.522011394421294 ADGRG1/ISL1/IL6ST 3 GO:0032613 interleukin-10 production 3/580 62/18722 0.301466911506256 0.522011394421294 CD46/PRKCZ/HMGB1 3 GO:0032653 regulation of interleukin-10 production 3/580 62/18722 0.301466911506256 0.522011394421294 CD46/PRKCZ/HMGB1 3 GO:0032757 positive regulation of interleukin-8 production 3/580 62/18722 0.301466911506256 0.522011394421294 HSPA1A/DDIT3/HMGB1 3 GO:0048663 neuron fate commitment 3/580 62/18722 0.301466911506256 0.522011394421294 ISL1/GLI3/CDC42 3 GO:0060113 inner ear receptor cell differentiation 3/580 62/18722 0.301466911506256 0.522011394421294 NAGLU/TRIP11/TRIOBP 3 GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 3/580 62/18722 0.301466911506256 0.522011394421294 LRP1/BMP7/CSNK2B 3 GO:0070265 necrotic cell death 3/580 62/18722 0.301466911506256 0.522011394421294 CAV1/NINJ1/PYGL 3 GO:0007613 memory 5/580 118/18722 0.302923048618091 0.522575786543888 SERPINF1/SLC6A4/EIF2AK4/LGMN/PRKCZ 5 GO:0071346 cellular response to interferon-gamma 5/580 118/18722 0.302923048618091 0.522575786543888 GAPDH/RPL13A/KIF5B/ACTG1/CDC42 5 GO:0034644 cellular response to UV 4/580 90/18722 0.304531189388416 0.522575786543888 DDB1/NPM1/EIF2AK4/PCNA 4 GO:0045638 negative regulation of myeloid cell differentiation 4/580 90/18722 0.304531189388416 0.522575786543888 FBN1/ZFP36L1/CDK6/NFKBIA 4 GO:0097581 lamellipodium organization 4/580 90/18722 0.304531189388416 0.522575786543888 ITGB1/KANK1/WASF2/CDC42 4 GO:1902652 secondary alcohol metabolic process 6/580 147/18722 0.304761449794126 0.522575786543888 APP/DHCR24/LRP5/HMGCR/POR/ACADVL 6 GO:0046700 heterocycle catabolic process 16/580 445/18722 0.306268220927949 0.522575786543888 KCNQ1OT1/HSPA1A/ZFP36L1/TNRC6A/YBX1/ROCK1/NPM1/PUM1/FUS/MGAT1/DUT/HNRNPC/HNRNPD/CIRBP/CARHSP1/SERBP1 16 GO:0036314 response to sterol 2/580 36/18722 0.307227430730861 0.522575786543888 DAG1/HMGCR 2 GO:0042092 type 2 immune response 2/580 36/18722 0.307227430730861 0.522575786543888 CD81/PRKCZ 2 GO:0045746 negative regulation of Notch signaling pathway 2/580 36/18722 0.307227430730861 0.522575786543888 BMP7/NFKBIA 2 GO:0060251 regulation of glial cell proliferation 2/580 36/18722 0.307227430730861 0.522575786543888 EGFR/UFL1 2 GO:0070897 transcription preinitiation complex assembly 2/580 36/18722 0.307227430730861 0.522575786543888 BDP1/HMGB1 2 GO:0071402 cellular response to lipoprotein particle stimulus 2/580 36/18722 0.307227430730861 0.522575786543888 ITGB1/CD81 2 GO:0090313 regulation of protein targeting to membrane 2/580 36/18722 0.307227430730861 0.522575786543888 TCAF1/STOM 2 GO:1901658 glycosyl compound catabolic process 2/580 36/18722 0.307227430730861 0.522575786543888 GUSB/FUCA1 2 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 2/580 36/18722 0.307227430730861 0.522575786543888 TPT1/MIF 2 GO:1903749 positive regulation of establishment of protein localization to mitochondrion 2/580 36/18722 0.307227430730861 0.522575786543888 LEPROT/UBE2L3 2 GO:0031398 positive regulation of protein ubiquitination 5/580 119/18722 0.308997915119948 0.522575786543888 HSPA5/MYCBP2/NPM1/CAV1/UBE2L3 5 GO:0071466 cellular response to xenobiotic stimulus 7/580 177/18722 0.309641065586209 0.522575786543888 EGFR/HSPA5/TFRC/POR/GSTO1/CYP2J2/PCNA 7 GO:0001947 heart looping 3/580 63/18722 0.309989686228164 0.522575786543888 FOLR1/TBX3/CITED2 3 GO:0002704 negative regulation of leukocyte mediated immunity 3/580 63/18722 0.309989686228164 0.522575786543888 CD46/CD55/SERPINB9 3 GO:0016072 rRNA metabolic process 9/580 236/18722 0.310168675313248 0.522575786543888 RPS21/RPS6/RPL7/RPS16/RPL14/RPS25/RPS17/PRKDC/FBL 9 GO:0050905 neuromuscular process 6/580 148/18722 0.310190761968994 0.522575786543888 GAA/APP/MYCBP2/IGDCC3/TMEM150C/GSTO1 6 GO:0097530 granulocyte migration 6/580 148/18722 0.310190761968994 0.522575786543888 CSF3R/BSG/DPP4/JAM3/PPIA/S100A9 6 GO:1903900 regulation of viral life cycle 6/580 148/18722 0.310190761968994 0.522575786543888 P4HB/DDB1/HACD3/PKN2/PPIA/MPHOSPH8 6 GO:0072521 purine-containing compound metabolic process 15/580 416/18722 0.310316147546234 0.522575786543888 GAPDH/SLC26A2/LDHA/APP/ALDOA/ENO1/TPST2/ACSS1/HMGCR/TPI1/CROT/TMSB4X/PKM/RHOA/RAN 15 GO:0002065 columnar/cuboidal epithelial cell differentiation 4/580 91/18722 0.311548610119129 0.522575786543888 SOX4/CDK6/IL6ST/TYMS 4 GO:0006885 regulation of pH 4/580 91/18722 0.311548610119129 0.522575786543888 GRN/ATP6AP1/SLC9A1/ATP6AP2 4 GO:0002024 diet induced thermogenesis 1/580 12/18722 0.314596853461666 0.522575786543888 ADRB1 1 GO:0002424 T cell mediated immune response to tumor cell 1/580 12/18722 0.314596853461666 0.522575786543888 HMGB1 1 GO:0002863 positive regulation of inflammatory response to antigenic stimulus 1/580 12/18722 0.314596853461666 0.522575786543888 CD81 1 GO:0002903 negative regulation of B cell apoptotic process 1/580 12/18722 0.314596853461666 0.522575786543888 SLC39A10 1 GO:0003207 cardiac chamber formation 1/580 12/18722 0.314596853461666 0.522575786543888 SOX4 1 GO:0006703 estrogen biosynthetic process 1/580 12/18722 0.314596853461666 0.522575786543888 HSD17B1 1 GO:0007320 insemination 1/580 12/18722 0.314596853461666 0.522575786543888 SLC6A4 1 GO:0007614 short-term memory 1/580 12/18722 0.314596853461666 0.522575786543888 SERPINF1 1 GO:0010587 miRNA catabolic process 1/580 12/18722 0.314596853461666 0.522575786543888 KCNQ1OT1 1 GO:0010623 programmed cell death involved in cell development 1/580 12/18722 0.314596853461666 0.522575786543888 PRKDC 1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway 1/580 12/18722 0.314596853461666 0.522575786543888 LRP1 1 GO:0010826 negative regulation of centrosome duplication 1/580 12/18722 0.314596853461666 0.522575786543888 NPM1 1 GO:0016554 cytidine to uridine editing 1/580 12/18722 0.314596853461666 0.522575786543888 RBM47 1 GO:0021527 spinal cord association neuron differentiation 1/580 12/18722 0.314596853461666 0.522575786543888 LMO4 1 GO:0021670 lateral ventricle development 1/580 12/18722 0.314596853461666 0.522575786543888 CDK6 1 GO:0021936 regulation of cerebellar granule cell precursor proliferation 1/580 12/18722 0.314596853461666 0.522575786543888 SLC6A4 1 GO:0030157 pancreatic juice secretion 1/580 12/18722 0.314596853461666 0.522575786543888 COPA 1 GO:0030238 male sex determination 1/580 12/18722 0.314596853461666 0.522575786543888 SF1 1 GO:0031126 sno(s)RNA 3'-end processing 1/580 12/18722 0.314596853461666 0.522575786543888 FBL 1 GO:0031953 negative regulation of protein autophosphorylation 1/580 12/18722 0.314596853461666 0.522575786543888 CAV1 1 GO:0032736 positive regulation of interleukin-13 production 1/580 12/18722 0.314596853461666 0.522575786543888 PRKCZ 1 GO:0032780 negative regulation of ATPase activity 1/580 12/18722 0.314596853461666 0.522575786543888 CNN3 1 GO:0032908 regulation of transforming growth factor beta1 production 1/580 12/18722 0.314596853461666 0.522575786543888 ATP6AP2 1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 1/580 12/18722 0.314596853461666 0.522575786543888 CROT 1 GO:0033629 negative regulation of cell adhesion mediated by integrin 1/580 12/18722 0.314596853461666 0.522575786543888 JAM3 1 GO:0035112 genitalia morphogenesis 1/580 12/18722 0.314596853461666 0.522575786543888 NIPBL 1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway 1/580 12/18722 0.314596853461666 0.522575786543888 COL4A2 1 GO:0042118 endothelial cell activation 1/580 12/18722 0.314596853461666 0.522575786543888 PPIA 1 GO:0043380 regulation of memory T cell differentiation 1/580 12/18722 0.314596853461666 0.522575786543888 CD46 1 GO:0043383 negative T cell selection 1/580 12/18722 0.314596853461666 0.522575786543888 GLI3 1 GO:0043471 regulation of cellular carbohydrate catabolic process 1/580 12/18722 0.314596853461666 0.522575786543888 HMGB1 1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 1/580 12/18722 0.314596853461666 0.522575786543888 PHIP 1 GO:0044650 adhesion of symbiont to host cell 1/580 12/18722 0.314596853461666 0.522575786543888 CD81 1 GO:0045602 negative regulation of endothelial cell differentiation 1/580 12/18722 0.314596853461666 0.522575786543888 ID1 1 GO:0045605 negative regulation of epidermal cell differentiation 1/580 12/18722 0.314596853461666 0.522575786543888 SRSF6 1 GO:0045683 negative regulation of epidermis development 1/580 12/18722 0.314596853461666 0.522575786543888 SRSF6 1 GO:0046322 negative regulation of fatty acid oxidation 1/580 12/18722 0.314596853461666 0.522575786543888 ACADVL 1 GO:0046541 saliva secretion 1/580 12/18722 0.314596853461666 0.522575786543888 KCNN4 1 GO:0046606 negative regulation of centrosome cycle 1/580 12/18722 0.314596853461666 0.522575786543888 NPM1 1 GO:0046831 regulation of RNA export from nucleus 1/580 12/18722 0.314596853461666 0.522575786543888 TPR 1 GO:0048934 peripheral nervous system neuron differentiation 1/580 12/18722 0.314596853461666 0.522575786543888 ISL1 1 GO:0048935 peripheral nervous system neuron development 1/580 12/18722 0.314596853461666 0.522575786543888 ISL1 1 GO:0051001 negative regulation of nitric-oxide synthase activity 1/580 12/18722 0.314596853461666 0.522575786543888 CAV1 1 GO:0051340 regulation of ligase activity 1/580 12/18722 0.314596853461666 0.522575786543888 TMSB4X 1 GO:0060009 Sertoli cell development 1/580 12/18722 0.314596853461666 0.522575786543888 ATRX 1 GO:0060221 retinal rod cell differentiation 1/580 12/18722 0.314596853461666 0.522575786543888 NAGLU 1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 1/580 12/18722 0.314596853461666 0.522575786543888 LRP1 1 GO:0060442 branching involved in prostate gland morphogenesis 1/580 12/18722 0.314596853461666 0.522575786543888 BMP7 1 GO:0060601 lateral sprouting from an epithelium 1/580 12/18722 0.314596853461666 0.522575786543888 BMP7 1 GO:0060788 ectodermal placode formation 1/580 12/18722 0.314596853461666 0.522575786543888 TBX3 1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1/580 12/18722 0.314596853461666 0.522575786543888 GLI3 1 GO:0061430 bone trabecula morphogenesis 1/580 12/18722 0.314596853461666 0.522575786543888 FBN2 1 GO:0061620 glycolytic process through glucose-6-phosphate 1/580 12/18722 0.314596853461666 0.522575786543888 ENO1 1 GO:0070170 regulation of tooth mineralization 1/580 12/18722 0.314596853461666 0.522575786543888 TFAP2A 1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain 1/580 12/18722 0.314596853461666 0.522575786543888 BRD4 1 GO:0071107 response to parathyroid hormone 1/580 12/18722 0.314596853461666 0.522575786543888 GJA1 1 GO:0071257 cellular response to electrical stimulus 1/580 12/18722 0.314596853461666 0.522575786543888 SLC9A1 1 GO:0071468 cellular response to acidic pH 1/580 12/18722 0.314596853461666 0.522575786543888 SLC9A1 1 GO:0071472 cellular response to salt stress 1/580 12/18722 0.314596853461666 0.522575786543888 ZFP36L1 1 GO:0071697 ectodermal placode morphogenesis 1/580 12/18722 0.314596853461666 0.522575786543888 TBX3 1 GO:0071872 cellular response to epinephrine stimulus 1/580 12/18722 0.314596853461666 0.522575786543888 SLC9A1 1 GO:0072015 glomerular visceral epithelial cell development 1/580 12/18722 0.314596853461666 0.522575786543888 IQGAP1 1 GO:0072376 protein activation cascade 1/580 12/18722 0.314596853461666 0.522575786543888 FBLN1 1 GO:0072584 caveolin-mediated endocytosis 1/580 12/18722 0.314596853461666 0.522575786543888 CAV1 1 GO:0072711 cellular response to hydroxyurea 1/580 12/18722 0.314596853461666 0.522575786543888 ATRX 1 GO:0086067 AV node cell to bundle of His cell communication 1/580 12/18722 0.314596853461666 0.522575786543888 GJA5 1 GO:0097152 mesenchymal cell apoptotic process 1/580 12/18722 0.314596853461666 0.522575786543888 BMP7 1 GO:0150065 regulation of deacetylase activity 1/580 12/18722 0.314596853461666 0.522575786543888 KDM5A 1 GO:1901298 regulation of hydrogen peroxide-mediated programmed cell death 1/580 12/18722 0.314596853461666 0.522575786543888 MET 1 GO:1901894 regulation of ATPase-coupled calcium transmembrane transporter activity 1/580 12/18722 0.314596853461666 0.522575786543888 C4orf3 1 GO:1902563 regulation of neutrophil activation 1/580 12/18722 0.314596853461666 0.522575786543888 GRN 1 GO:1903599 positive regulation of autophagy of mitochondrion 1/580 12/18722 0.314596853461666 0.522575786543888 VDAC1 1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA 1/580 12/18722 0.314596853461666 0.522575786543888 EGFR 1 GO:1903909 regulation of receptor clustering 1/580 12/18722 0.314596853461666 0.522575786543888 CD81 1 GO:1904748 regulation of apoptotic process involved in development 1/580 12/18722 0.314596853461666 0.522575786543888 BMP7 1 GO:1905205 positive regulation of connective tissue replacement 1/580 12/18722 0.314596853461666 0.522575786543888 ROCK1 1 GO:1905214 regulation of RNA binding 1/580 12/18722 0.314596853461666 0.522575786543888 EIF4G1 1 GO:1905245 regulation of aspartic-type peptidase activity 1/580 12/18722 0.314596853461666 0.522575786543888 GRN 1 GO:1905709 negative regulation of membrane permeability 1/580 12/18722 0.314596853461666 0.522575786543888 DYNLT1 1 GO:2000009 negative regulation of protein localization to cell surface 1/580 12/18722 0.314596853461666 0.522575786543888 LEPROT 1 GO:2000035 regulation of stem cell division 1/580 12/18722 0.314596853461666 0.522575786543888 NCOA3 1 GO:2000105 positive regulation of DNA-dependent DNA replication 1/580 12/18722 0.314596853461666 0.522575786543888 ATRX 1 GO:2000303 regulation of ceramide biosynthetic process 1/580 12/18722 0.314596853461666 0.522575786543888 ORMDL1 1 GO:2000628 regulation of miRNA metabolic process 1/580 12/18722 0.314596853461666 0.522575786543888 KCNQ1OT1 1 GO:2001214 positive regulation of vasculogenesis 1/580 12/18722 0.314596853461666 0.522575786543888 ADM 1 GO:0006109 regulation of carbohydrate metabolic process 7/580 178/18722 0.31460163455663 0.522575786543888 APP/DDB1/PMAIP1/PHLDA2/PGP/HMGB1/IGF2 7 GO:0072655 establishment of protein localization to mitochondrion 5/580 120/18722 0.315089782257863 0.523199777679872 LMAN1/DDIT3/CALM1/LEPROT/UBE2L3 5 GO:0001885 endothelial cell development 3/580 64/18722 0.318519701795616 0.526415038207295 MET/ROCK1/GPX1 3 GO:0006940 regulation of smooth muscle contraction 3/580 64/18722 0.318519701795616 0.526415038207295 ATP2B1/CAV1/RHOA 3 GO:0016126 sterol biosynthetic process 3/580 64/18722 0.318519701795616 0.526415038207295 DHCR24/HMGCR/POR 3 GO:0050771 negative regulation of axonogenesis 3/580 64/18722 0.318519701795616 0.526415038207295 SEMA6A/SEMA6D/RTN4 3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2/580 37/18722 0.318723876067887 0.526415038207295 RPS21/RPS16 2 GO:0006623 protein targeting to vacuole 2/580 37/18722 0.318723876067887 0.526415038207295 GCC2/HSPA8 2 GO:0014904 myotube cell development 2/580 37/18722 0.318723876067887 0.526415038207295 PLEC/GPX1 2 GO:0021532 neural tube patterning 2/580 37/18722 0.318723876067887 0.526415038207295 GLI3/ATP6AP2 2 GO:0042178 xenobiotic catabolic process 2/580 37/18722 0.318723876067887 0.526415038207295 GSTO1/CYP2J2 2 GO:0043029 T cell homeostasis 2/580 37/18722 0.318723876067887 0.526415038207295 RPS6/PMAIP1 2 GO:0060428 lung epithelium development 2/580 37/18722 0.318723876067887 0.526415038207295 SRSF6/CDC42 2 GO:0090218 positive regulation of lipid kinase activity 2/580 37/18722 0.318723876067887 0.526415038207295 CD81/CDC42 2 GO:1900077 negative regulation of cellular response to insulin stimulus 2/580 37/18722 0.318723876067887 0.526415038207295 KANK1/PRKCZ 2 GO:1902745 positive regulation of lamellipodium organization 2/580 37/18722 0.318723876067887 0.526415038207295 WASF2/CDC42 2 GO:1904358 positive regulation of telomere maintenance via telomere lengthening 2/580 37/18722 0.318723876067887 0.526415038207295 HNRNPA1/HNRNPA2B1 2 GO:0001894 tissue homeostasis 10/580 268/18722 0.319436844469947 0.527405311902636 EGFR/LAMC1/ITGB1/SLC2A1/GJA1/LSR/ATP6AP1/TFRC/JAM3/ACTG1 10 GO:0007626 locomotory behavior 7/580 179/18722 0.31957662067519 0.527448851227931 GAA/EGR1/NAGLU/APP/DPP4/ZFHX3/PUM1 7 GO:0038127 ERBB signaling pathway 5/580 121/18722 0.321196916950195 0.529747113735942 EGFR/EFEMP1/IQGAP1/RTN4/LGMN 5 GO:0043500 muscle adaptation 5/580 121/18722 0.321196916950195 0.529747113735942 DAG1/SLC9A1/ROCK1/IL6ST/CYBA 5 GO:0031497 chromatin assembly 6/580 151/18722 0.326570846800727 0.535301704153917 ATRX/NPM1/RSF1/HMGB1/HMGB2/DNAJC9 6 GO:0055067 monovalent inorganic cation homeostasis 6/580 151/18722 0.326570846800727 0.535301704153917 GRN/SLC12A9/ATP6AP1/SLC9A1/ATP6AP2/GNAI2 6 GO:0002720 positive regulation of cytokine production involved in immune response 3/580 65/18722 0.327052578408612 0.535301704153917 CD81/CD55/PRKCZ 3 GO:0015909 long-chain fatty acid transport 3/580 65/18722 0.327052578408612 0.535301704153917 SLC2A1/SLC27A2/PLIN2 3 GO:0038034 signal transduction in absence of ligand 3/580 65/18722 0.327052578408612 0.535301704153917 ITGAV/HSPA1A/ERBB3 3 GO:0045453 bone resorption 3/580 65/18722 0.327052578408612 0.535301704153917 EGFR/ATP6AP1/TFRC 3 GO:0051310 metaphase plate congression 3/580 65/18722 0.327052578408612 0.535301704153917 DYNC1H1/CENPF/RAB11A 3 GO:0070613 regulation of protein processing 3/580 65/18722 0.327052578408612 0.535301704153917 GLG1/ENO1/TMEM59 3 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 3/580 65/18722 0.327052578408612 0.535301704153917 ITGAV/HSPA1A/ERBB3 3 GO:0031109 microtubule polymerization or depolymerization 5/580 122/18722 0.327317602680096 0.535301704153917 AKAP9/CLIP1/MET/HSPA1A/STMN1 5 GO:0097696 receptor signaling pathway via STAT 7/580 181/18722 0.329566092178476 0.535301704153917 ISL1/IL10RB/CSH1/PRLR/CAV1/IL6ST/LEPROT 7 GO:0010742 macrophage derived foam cell differentiation 2/580 38/18722 0.3301741585606 0.535301704153917 ITGAV/NFKBIA 2 GO:0032717 negative regulation of interleukin-8 production 2/580 38/18722 0.3301741585606 0.535301704153917 TMSB4X/ANXA4 2 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway 2/580 38/18722 0.3301741585606 0.535301704153917 ISL1/RHOA 2 GO:0046633 alpha-beta T cell proliferation 2/580 38/18722 0.3301741585606 0.535301704153917 CD81/CD55 2 GO:0090077 foam cell differentiation 2/580 38/18722 0.3301741585606 0.535301704153917 ITGAV/NFKBIA 2 GO:0016125 sterol metabolic process 6/580 152/18722 0.33205747330744 0.535301704153917 APP/DHCR24/LRP5/HMGCR/POR/ACADVL 6 GO:0031570 DNA integrity checkpoint signaling 5/580 123/18722 0.333450140475949 0.535301704153917 SOX4/PPP1R10/PRKDC/EIF2AK4/CDK1 5 GO:0006303 double-strand break repair via nonhomologous end joining 3/580 66/18722 0.335584068436689 0.535301704153917 PRKDC/HMGB1/HMGB2 3 GO:0050766 positive regulation of phagocytosis 3/580 66/18722 0.335584068436689 0.535301704153917 LRP1/LMAN2/CYBA 3 GO:0072678 T cell migration 3/580 66/18722 0.335584068436689 0.535301704153917 APP/PLEC/RHOA 3 GO:2000573 positive regulation of DNA biosynthetic process 3/580 66/18722 0.335584068436689 0.535301704153917 HNRNPA1/PTGES3/PCNA 3 GO:0030258 lipid modification 8/580 212/18722 0.335746803501802 0.535301704153917 PLPP3/ILVBL/SLC27A2/POR/CROT/ECHDC2/ACADVL/HADHA 8 GO:0001886 endothelial cell morphogenesis 1/580 13/18722 0.335843984674506 0.535301704153917 MET 1 GO:0001973 G protein-coupled adenosine receptor signaling pathway 1/580 13/18722 0.335843984674506 0.535301704153917 GNAI2 1 GO:0002638 negative regulation of immunoglobulin production 1/580 13/18722 0.335843984674506 0.535301704153917 PRKDC 1 GO:0003334 keratinocyte development 1/580 13/18722 0.335843984674506 0.535301704153917 PLEC 1 GO:0006000 fructose metabolic process 1/580 13/18722 0.335843984674506 0.535301704153917 ALDOA 1 GO:0007494 midgut development 1/580 13/18722 0.335843984674506 0.535301704153917 EGFR 1 GO:0007567 parturition 1/580 13/18722 0.335843984674506 0.535301704153917 HPGD 1 GO:0008298 intracellular mRNA localization 1/580 13/18722 0.335843984674506 0.535301704153917 ZFP36L1 1 GO:0009143 nucleoside triphosphate catabolic process 1/580 13/18722 0.335843984674506 0.535301704153917 DUT 1 GO:0009650 UV protection 1/580 13/18722 0.335843984674506 0.535301704153917 GPX1 1 GO:0010635 regulation of mitochondrial fusion 1/580 13/18722 0.335843984674506 0.535301704153917 TFRC 1 GO:0010755 regulation of plasminogen activation 1/580 13/18722 0.335843984674506 0.535301704153917 ENO1 1 GO:0010960 magnesium ion homeostasis 1/580 13/18722 0.335843984674506 0.535301704153917 EGFR 1 GO:0015801 aromatic amino acid transport 1/580 13/18722 0.335843984674506 0.535301704153917 SLC3A2 1 GO:0015809 arginine transport 1/580 13/18722 0.335843984674506 0.535301704153917 SLC38A9 1 GO:0016322 neuron remodeling 1/580 13/18722 0.335843984674506 0.535301704153917 APP 1 GO:0021554 optic nerve development 1/580 13/18722 0.335843984674506 0.535301704153917 GLI3 1 GO:0030497 fatty acid elongation 1/580 13/18722 0.335843984674506 0.535301704153917 HACD3 1 GO:0031053 primary miRNA processing 1/580 13/18722 0.335843984674506 0.535301704153917 HNRNPA2B1 1 GO:0031272 regulation of pseudopodium assembly 1/580 13/18722 0.335843984674506 0.535301704153917 CDC42 1 GO:0031274 positive regulation of pseudopodium assembly 1/580 13/18722 0.335843984674506 0.535301704153917 CDC42 1 GO:0032230 positive regulation of synaptic transmission, GABAergic 1/580 13/18722 0.335843984674506 0.535301704153917 KIF5B 1 GO:0032252 secretory granule localization 1/580 13/18722 0.335843984674506 0.535301704153917 KIF5B 1 GO:0032905 transforming growth factor beta1 production 1/580 13/18722 0.335843984674506 0.535301704153917 ATP6AP2 1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter 1/580 13/18722 0.335843984674506 0.535301704153917 BRD4 1 GO:0033262 regulation of nuclear cell cycle DNA replication 1/580 13/18722 0.335843984674506 0.535301704153917 ATRX 1 GO:0033689 negative regulation of osteoblast proliferation 1/580 13/18722 0.335843984674506 0.535301704153917 ATRAID 1 GO:0034112 positive regulation of homotypic cell-cell adhesion 1/580 13/18722 0.335843984674506 0.535301704153917 IL6ST 1 GO:0035588 G protein-coupled purinergic receptor signaling pathway 1/580 13/18722 0.335843984674506 0.535301704153917 GNAI2 1 GO:0036302 atrioventricular canal development 1/580 13/18722 0.335843984674506 0.535301704153917 TBX3 1 GO:0036462 TRAIL-activated apoptotic signaling pathway 1/580 13/18722 0.335843984674506 0.535301704153917 TIMP3 1 GO:0042308 negative regulation of protein import into nucleus 1/580 13/18722 0.335843984674506 0.535301704153917 FERMT1 1 GO:0042492 gamma-delta T cell differentiation 1/580 13/18722 0.335843984674506 0.535301704153917 SOX4 1 GO:0042659 regulation of cell fate specification 1/580 13/18722 0.335843984674506 0.535301704153917 LMO4 1 GO:0042761 very long-chain fatty acid biosynthetic process 1/580 13/18722 0.335843984674506 0.535301704153917 HACD3 1 GO:0042769 DNA damage response, detection of DNA damage 1/580 13/18722 0.335843984674506 0.535301704153917 SOX4 1 GO:0043379 memory T cell differentiation 1/580 13/18722 0.335843984674506 0.535301704153917 CD46 1 GO:0044090 positive regulation of vacuole organization 1/580 13/18722 0.335843984674506 0.535301704153917 GRN 1 GO:0046415 urate metabolic process 1/580 13/18722 0.335843984674506 0.535301704153917 SLC22A11 1 GO:0046689 response to mercury ion 1/580 13/18722 0.335843984674506 0.535301704153917 BSG 1 GO:0048266 behavioral response to pain 1/580 13/18722 0.335843984674506 0.535301704153917 VWA1 1 GO:0048711 positive regulation of astrocyte differentiation 1/580 13/18722 0.335843984674506 0.535301704153917 IL6ST 1 GO:0048820 hair follicle maturation 1/580 13/18722 0.335843984674506 0.535301704153917 FERMT1 1 GO:0051451 myoblast migration 1/580 13/18722 0.335843984674506 0.535301704153917 ROCK1 1 GO:0051709 regulation of killing of cells of other organism 1/580 13/18722 0.335843984674506 0.535301704153917 SERPINB9 1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore 1/580 13/18722 0.335843984674506 0.535301704153917 CDC42 1 GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1/580 13/18722 0.335843984674506 0.535301704153917 TNRC6A 1 GO:0061615 glycolytic process through fructose-6-phosphate 1/580 13/18722 0.335843984674506 0.535301704153917 ENO1 1 GO:0061744 motor behavior 1/580 13/18722 0.335843984674506 0.535301704153917 DPP4 1 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway 1/580 13/18722 0.335843984674506 0.535301704153917 HSPA1A 1 GO:0070914 UV-damage excision repair 1/580 13/18722 0.335843984674506 0.535301704153917 DDB1 1 GO:0071696 ectodermal placode development 1/580 13/18722 0.335843984674506 0.535301704153917 TBX3 1 GO:0071801 regulation of podosome assembly 1/580 13/18722 0.335843984674506 0.535301704153917 RHOA 1 GO:0072310 glomerular epithelial cell development 1/580 13/18722 0.335843984674506 0.535301704153917 IQGAP1 1 GO:0072710 response to hydroxyurea 1/580 13/18722 0.335843984674506 0.535301704153917 ATRX 1 GO:0090153 regulation of sphingolipid biosynthetic process 1/580 13/18722 0.335843984674506 0.535301704153917 ORMDL1 1 GO:0090158 endoplasmic reticulum membrane organization 1/580 13/18722 0.335843984674506 0.535301704153917 RTN4 1 GO:0098840 protein transport along microtubule 1/580 13/18722 0.335843984674506 0.535301704153917 KIF5B 1 GO:0099118 microtubule-based protein transport 1/580 13/18722 0.335843984674506 0.535301704153917 KIF5B 1 GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 1/580 13/18722 0.335843984674506 0.535301704153917 GNAI2 1 GO:0106074 aminoacyl-tRNA metabolism involved in translational fidelity 1/580 13/18722 0.335843984674506 0.535301704153917 IARS2 1 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response 1/580 13/18722 0.335843984674506 0.535301704153917 XBP1 1 GO:1900121 negative regulation of receptor binding 1/580 13/18722 0.335843984674506 0.535301704153917 PTPRF 1 GO:1900272 negative regulation of long-term synaptic potentiation 1/580 13/18722 0.335843984674506 0.535301704153917 APP 1 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance 1/580 13/18722 0.335843984674506 0.535301704153917 NRP2 1 GO:1902947 regulation of tau-protein kinase activity 1/580 13/18722 0.335843984674506 0.535301704153917 EGR1 1 GO:1903054 negative regulation of extracellular matrix organization 1/580 13/18722 0.335843984674506 0.535301704153917 DPP4 1 GO:1903977 positive regulation of glial cell migration 1/580 13/18722 0.335843984674506 0.535301704153917 LRP1 1 GO:1904590 negative regulation of protein import 1/580 13/18722 0.335843984674506 0.535301704153917 FERMT1 1 GO:1905038 regulation of membrane lipid metabolic process 1/580 13/18722 0.335843984674506 0.535301704153917 ORMDL1 1 GO:1905203 regulation of connective tissue replacement 1/580 13/18722 0.335843984674506 0.535301704153917 ROCK1 1 GO:1905939 regulation of gonad development 1/580 13/18722 0.335843984674506 0.535301704153917 CITED2 1 GO:1990403 embryonic brain development 1/580 13/18722 0.335843984674506 0.535301704153917 TRA2B 1 GO:2001023 regulation of response to drug 1/580 13/18722 0.335843984674506 0.535301704153917 ADIRF 1 GO:2001198 regulation of dendritic cell differentiation 1/580 13/18722 0.335843984674506 0.535301704153917 HMGB1 1 GO:0010508 positive regulation of autophagy 5/580 124/18722 0.339592849843441 0.541091587743009 UFL1/ROCK1/TMEM59/HMGB1/VDAC1 5 GO:0008585 female gonad development 4/580 95/18722 0.339741423246071 0.541142931341601 HSPA5/ADAMTS1/NR2F2/ARID5B 4 GO:0043583 ear development 8/580 213/18722 0.340397728253562 0.542002681994973 NAGLU/LGR5/GLI3/TRIP11/LRP10/NIPBL/TRIOBP/TFAP2A 8 GO:0002347 response to tumor cell 2/580 39/18722 0.341570113710688 0.542013851541593 HMGB1/TXNIP 2 GO:0007618 mating 2/580 39/18722 0.341570113710688 0.542013851541593 APP/SLC6A4 2 GO:0016233 telomere capping 2/580 39/18722 0.341570113710688 0.542013851541593 PRKDC/HNRNPD 2 GO:0031507 heterochromatin assembly 2/580 39/18722 0.341570113710688 0.542013851541593 TPR/MPHOSPH8 2 GO:0032506 cytokinetic process 2/580 39/18722 0.341570113710688 0.542013851541593 PLEC/RHOA 2 GO:0032728 positive regulation of interferon-beta production 2/580 39/18722 0.341570113710688 0.542013851541593 HMGB1/HMGB2 2 GO:0034314 Arp2/3 complex-mediated actin nucleation 2/580 39/18722 0.341570113710688 0.542013851541593 IQGAP2/WASF2 2 GO:0045823 positive regulation of heart contraction 2/580 39/18722 0.341570113710688 0.542013851541593 ADRB1/ADM 2 GO:0051154 negative regulation of striated muscle cell differentiation 2/580 39/18722 0.341570113710688 0.542013851541593 YBX1/XBP1 2 GO:1902742 apoptotic process involved in development 2/580 39/18722 0.341570113710688 0.542013851541593 LRP5/BMP7 2 GO:0009880 embryonic pattern specification 3/580 67/18722 0.34411005650886 0.544928795649543 NRP2/TBX3/BMP7 3 GO:0032890 regulation of organic acid transport 3/580 67/18722 0.34411005650886 0.544928795649543 ITGB1/SLC43A2/ARL6IP5 3 GO:0042490 mechanoreceptor differentiation 3/580 67/18722 0.34411005650886 0.544928795649543 NAGLU/TRIP11/TRIOBP 3 GO:0048814 regulation of dendrite morphogenesis 3/580 67/18722 0.34411005650886 0.544928795649543 CUX1/ID1/YWHAH 3 GO:0050435 amyloid-beta metabolic process 3/580 67/18722 0.34411005650886 0.544928795649543 NCSTN/ROCK1/RTN4 3 GO:0061371 determination of heart left/right asymmetry 3/580 67/18722 0.34411005650886 0.544928795649543 FOLR1/TBX3/CITED2 3 GO:0070585 protein localization to mitochondrion 5/580 125/18722 0.345744069649942 0.547330043547271 LMAN1/DDIT3/CALM1/LEPROT/UBE2L3 5 GO:0035282 segmentation 4/580 96/18722 0.346807786052746 0.548640480588885 NRP2/PRKDC/IRX2/TBX3 4 GO:0051304 chromosome separation 4/580 96/18722 0.346807786052746 0.548640480588885 DUSP1/CENPF/TPR/ANAPC11 4 GO:0002366 leukocyte activation involved in immune response 10/580 275/18722 0.348040061113883 0.550402694403492 GRN/RPS6/CD46/TFRC/CD81/EIF2AK4/VAMP2/XBP1/PRKCZ/HMGB1 10 GO:0002040 sprouting angiogenesis 7/580 185/18722 0.34967696932826 0.550754989507268 SEMA6A/ITGB1/EPHB4/PKM/RHOA/HMGB1/CDC42 7 GO:0009206 purine ribonucleoside triphosphate biosynthetic process 3/580 68/18722 0.352626559346789 0.550754989507268 ALDOA/ENO1/TMSB4X 3 GO:0042267 natural killer cell mediated cytotoxicity 3/580 68/18722 0.352626559346789 0.550754989507268 CADM1/KIF5B/SERPINB9 3 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 3/580 68/18722 0.352626559346789 0.550754989507268 ISL1/CSH1/IL6ST 3 GO:0051148 negative regulation of muscle cell differentiation 3/580 68/18722 0.352626559346789 0.550754989507268 YBX1/XBP1/IGF2 3 GO:0009394 2'-deoxyribonucleotide metabolic process 2/580 40/18722 0.352904125423702 0.550754989507268 DUT/TYMS 2 GO:0010863 positive regulation of phospholipase C activity 2/580 40/18722 0.352904125423702 0.550754989507268 EGFR/GNAQ 2 GO:0030866 cortical actin cytoskeleton organization 2/580 40/18722 0.352904125423702 0.550754989507268 PLEC/ROCK1 2 GO:0035329 hippo signaling 2/580 40/18722 0.352904125423702 0.550754989507268 DLG5/VGLL4 2 GO:0046365 monosaccharide catabolic process 2/580 40/18722 0.352904125423702 0.550754989507268 ENO1/LRP5 2 GO:0070266 necroptotic process 2/580 40/18722 0.352904125423702 0.550754989507268 CAV1/PYGL 2 GO:0150077 regulation of neuroinflammatory response 2/580 40/18722 0.352904125423702 0.550754989507268 GRN/CTSC 2 GO:1901223 negative regulation of NIK/NF-kappaB signaling 2/580 40/18722 0.352904125423702 0.550754989507268 BMP7/TMSB4X 2 GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell 2/580 40/18722 0.352904125423702 0.550754989507268 NFAT5/RHOA 2 GO:2000142 regulation of DNA-templated transcription, initiation 2/580 40/18722 0.352904125423702 0.550754989507268 JUN/HMGB1 2 GO:2000781 positive regulation of double-strand break repair 2/580 40/18722 0.352904125423702 0.550754989507268 PRKDC/FUS 2 GO:0001764 neuron migration 6/580 156/18722 0.354104514002013 0.550754989507268 NRP2/SEMA6A/ADGRG1/NR2F2/NIPBL/ASPM 6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 7/580 186/18722 0.354726796451295 0.550754989507268 GAPDH/WLS/GJA1/TFRC/BRD4/TMED4/RHOA 7 GO:0001771 immunological synapse formation 1/580 14/18722 0.356433566634461 0.550754989507268 CD81 1 GO:0002091 negative regulation of receptor internalization 1/580 14/18722 0.356433566634461 0.550754989507268 LRPAP1 1 GO:0003188 heart valve formation 1/580 14/18722 0.356433566634461 0.550754989507268 GJA5 1 GO:0006047 UDP-N-acetylglucosamine metabolic process 1/580 14/18722 0.356433566634461 0.550754989507268 MGAT1 1 GO:0006287 base-excision repair, gap-filling 1/580 14/18722 0.356433566634461 0.550754989507268 PCNA 1 GO:0006465 signal peptide processing 1/580 14/18722 0.356433566634461 0.550754989507268 HM13 1 GO:0007100 mitotic centrosome separation 1/580 14/18722 0.356433566634461 0.550754989507268 RANBP1 1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity 1/580 14/18722 0.356433566634461 0.550754989507268 PRLR 1 GO:0009071 serine family amino acid catabolic process 1/580 14/18722 0.356433566634461 0.550754989507268 GLDC 1 GO:0010421 hydrogen peroxide-mediated programmed cell death 1/580 14/18722 0.356433566634461 0.550754989507268 MET 1 GO:0010989 negative regulation of low-density lipoprotein particle clearance 1/580 14/18722 0.356433566634461 0.550754989507268 MYLIP 1 GO:0014874 response to stimulus involved in regulation of muscle adaptation 1/580 14/18722 0.356433566634461 0.550754989507268 DAG1 1 GO:0018158 protein oxidation 1/580 14/18722 0.356433566634461 0.550754989507268 GPX1 1 GO:0031115 negative regulation of microtubule polymerization 1/580 14/18722 0.356433566634461 0.550754989507268 STMN1 1 GO:0035563 positive regulation of chromatin binding 1/580 14/18722 0.356433566634461 0.550754989507268 GMNN 1 GO:0035641 locomotory exploration behavior 1/580 14/18722 0.356433566634461 0.550754989507268 DPP4 1 GO:0035672 oligopeptide transmembrane transport 1/580 14/18722 0.356433566634461 0.550754989507268 GJA1 1 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway 1/580 14/18722 0.356433566634461 0.550754989507268 LRP1 1 GO:0035810 positive regulation of urine volume 1/580 14/18722 0.356433566634461 0.550754989507268 GNAI2 1 GO:0035815 positive regulation of renal sodium excretion 1/580 14/18722 0.356433566634461 0.550754989507268 GNAI2 1 GO:0036444 calcium import into the mitochondrion 1/580 14/18722 0.356433566634461 0.550754989507268 VDAC1 1 GO:0038183 bile acid signaling pathway 1/580 14/18722 0.356433566634461 0.550754989507268 HMGCR 1 GO:0043144 sno(s)RNA processing 1/580 14/18722 0.356433566634461 0.550754989507268 FBL 1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 1/580 14/18722 0.356433566634461 0.550754989507268 PMAIP1 1 GO:0043922 negative regulation by host of viral transcription 1/580 14/18722 0.356433566634461 0.550754989507268 JUN 1 GO:0045472 response to ether 1/580 14/18722 0.356433566634461 0.550754989507268 HNRNPD 1 GO:0045579 positive regulation of B cell differentiation 1/580 14/18722 0.356433566634461 0.550754989507268 XBP1 1 GO:0045989 positive regulation of striated muscle contraction 1/580 14/18722 0.356433566634461 0.550754989507268 GSTO1 1 GO:0046348 amino sugar catabolic process 1/580 14/18722 0.356433566634461 0.550754989507268 MGAT1 1 GO:0048368 lateral mesoderm development 1/580 14/18722 0.356433566634461 0.550754989507268 CITED2 1 GO:0055057 neuroblast division 1/580 14/18722 0.356433566634461 0.550754989507268 ASPM 1 GO:0060081 membrane hyperpolarization 1/580 14/18722 0.356433566634461 0.550754989507268 PRKCZ 1 GO:0060088 auditory receptor cell stereocilium organization 1/580 14/18722 0.356433566634461 0.550754989507268 TRIOBP 1 GO:0061043 regulation of vascular wound healing 1/580 14/18722 0.356433566634461 0.550754989507268 XBP1 1 GO:0061709 reticulophagy 1/580 14/18722 0.356433566634461 0.550754989507268 UFL1 1 GO:0070141 response to UV-A 1/580 14/18722 0.356433566634461 0.550754989507268 EGFR 1 GO:0070986 left/right axis specification 1/580 14/18722 0.356433566634461 0.550754989507268 CITED2 1 GO:0071285 cellular response to lithium ion 1/580 14/18722 0.356433566634461 0.550754989507268 CDH1 1 GO:0071481 cellular response to X-ray 1/580 14/18722 0.356433566634461 0.550754989507268 NIPBL 1 GO:0072176 nephric duct development 1/580 14/18722 0.356433566634461 0.550754989507268 GPC3 1 GO:0072498 embryonic skeletal joint development 1/580 14/18722 0.356433566634461 0.550754989507268 BMP7 1 GO:0072531 pyrimidine-containing compound transmembrane transport 1/580 14/18722 0.356433566634461 0.550754989507268 SLC25A36 1 GO:0090281 negative regulation of calcium ion import 1/580 14/18722 0.356433566634461 0.550754989507268 VDAC1 1 GO:0090308 regulation of DNA methylation-dependent heterochromatin assembly 1/580 14/18722 0.356433566634461 0.550754989507268 MPHOSPH8 1 GO:0090715 immunological memory formation process 1/580 14/18722 0.356433566634461 0.550754989507268 CD46 1 GO:0099638 endosome to plasma membrane protein transport 1/580 14/18722 0.356433566634461 0.550754989507268 RAB11A 1 GO:1900037 regulation of cellular response to hypoxia 1/580 14/18722 0.356433566634461 0.550754989507268 ENO1 1 GO:1901857 positive regulation of cellular respiration 1/580 14/18722 0.356433566634461 0.550754989507268 IL10RB 1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/580 14/18722 0.356433566634461 0.550754989507268 MIF 1 GO:1904152 regulation of retrograde protein transport, ER to cytosol 1/580 14/18722 0.356433566634461 0.550754989507268 OS9 1 GO:1905208 negative regulation of cardiocyte differentiation 1/580 14/18722 0.356433566634461 0.550754989507268 EGFR 1 GO:0061136 regulation of proteasomal protein catabolic process 7/580 187/18722 0.35978364327719 0.555746836560017 UFL1/HSPA1A/TMEM259/HECTD1/CAV1/EIF3H/GPX1 7 GO:0032642 regulation of chemokine production 4/580 98/18722 0.360945272168554 0.556347914095106 LRP1/EGR1/APP/HMGB1 4 GO:0043502 regulation of muscle adaptation 4/580 98/18722 0.360945272168554 0.556347914095106 DAG1/SLC9A1/ROCK1/IL6ST 4 GO:0003143 embryonic heart tube morphogenesis 3/580 69/18722 0.361129725360809 0.556347914095106 FOLR1/TBX3/CITED2 3 GO:0007004 telomere maintenance via telomerase 3/580 69/18722 0.361129725360809 0.556347914095106 HNRNPA1/PTGES3/HNRNPC 3 GO:0009145 purine nucleoside triphosphate biosynthetic process 3/580 69/18722 0.361129725360809 0.556347914095106 ALDOA/ENO1/TMSB4X 3 GO:0010611 regulation of cardiac muscle hypertrophy 3/580 69/18722 0.361129725360809 0.556347914095106 SLC9A1/ROCK1/IL6ST 3 GO:0031060 regulation of histone methylation 3/580 69/18722 0.361129725360809 0.556347914095106 ATRX/BRD4/NSD1 3 GO:0033344 cholesterol efflux 3/580 69/18722 0.361129725360809 0.556347914095106 LRP1/CAV1/NFKBIA 3 GO:0001953 negative regulation of cell-matrix adhesion 2/580 41/18722 0.364169099966722 0.558169786487949 LRP1/RASA1 2 GO:0032735 positive regulation of interleukin-12 production 2/580 41/18722 0.364169099966722 0.558169786487949 ISL1/HMGB1 2 GO:0048286 lung alveolus development 2/580 41/18722 0.364169099966722 0.558169786487949 MAN1A2/PTGES3 2 GO:0055023 positive regulation of cardiac muscle tissue growth 2/580 41/18722 0.364169099966722 0.558169786487949 TGFBR3/CDK1 2 GO:0071470 cellular response to osmotic stress 2/580 41/18722 0.364169099966722 0.558169786487949 SLC2A1/ZFP36L1 2 GO:1900371 regulation of purine nucleotide biosynthetic process 2/580 41/18722 0.364169099966722 0.558169786487949 ENO1/TMSB4X 2 GO:1901385 regulation of voltage-gated calcium channel activity 2/580 41/18722 0.364169099966722 0.558169786487949 AHNAK/CALM1 2 GO:1902622 regulation of neutrophil migration 2/580 41/18722 0.364169099966722 0.558169786487949 DPP4/JAM3 2 GO:1903524 positive regulation of blood circulation 2/580 41/18722 0.364169099966722 0.558169786487949 ADRB1/ADM 2 GO:1905314 semi-lunar valve development 2/580 41/18722 0.364169099966722 0.558169786487949 GJA5/ROCK1 2 GO:1905521 regulation of macrophage migration 2/580 41/18722 0.364169099966722 0.558169786487949 CD81/MIF 2 GO:0032612 interleukin-1 production 5/580 128/18722 0.364232488065131 0.558169786487949 EGR1/APP/ISL1/HMGB1/SERPINB1 5 GO:0032652 regulation of interleukin-1 production 5/580 128/18722 0.364232488065131 0.558169786487949 EGR1/APP/ISL1/HMGB1/SERPINB1 5 GO:0033865 nucleoside bisphosphate metabolic process 5/580 128/18722 0.364232488065131 0.558169786487949 SLC26A2/TPST2/ACSS1/HMGCR/CROT 5 GO:0033875 ribonucleoside bisphosphate metabolic process 5/580 128/18722 0.364232488065131 0.558169786487949 SLC26A2/TPST2/ACSS1/HMGCR/CROT 5 GO:0034032 purine nucleoside bisphosphate metabolic process 5/580 128/18722 0.364232488065131 0.558169786487949 SLC26A2/TPST2/ACSS1/HMGCR/CROT 5 GO:0048839 inner ear development 7/580 188/18722 0.364846608359651 0.558217758354584 NAGLU/LGR5/GLI3/TRIP11/LRP10/TRIOBP/TFAP2A 7 GO:1901361 organic cyclic compound catabolic process 17/580 495/18722 0.3663796472868 0.558217758354584 KCNQ1OT1/HSPA1A/ZFP36L1/TNRC6A/YBX1/ROCK1/NPM1/PUM1/FUS/MGAT1/DUT/HNRNPC/HNRNPD/CIRBP/YWHAH/CARHSP1/SERBP1 17 GO:0010717 regulation of epithelial to mesenchymal transition 4/580 99/18722 0.368011720007974 0.558217758354584 DAG1/ISL1/TCF7L2/BMP7 4 GO:0021510 spinal cord development 4/580 99/18722 0.368011720007974 0.558217758354584 SOX4/ISL1/GLI3/LMO4 4 GO:0021549 cerebellum development 4/580 99/18722 0.368011720007974 0.558217758354584 HSPA5/NAGLU/NCSTN/HNRNPD 4 GO:0030838 positive regulation of actin filament polymerization 4/580 99/18722 0.368011720007974 0.558217758354584 IQGAP2/WASF2/PFN1/RHOA 4 GO:0032602 chemokine production 4/580 99/18722 0.368011720007974 0.558217758354584 LRP1/EGR1/APP/HMGB1 4 GO:0042100 B cell proliferation 4/580 99/18722 0.368011720007974 0.558217758354584 SLC39A10/TFRC/CD81/MIF 4 GO:0071805 potassium ion transmembrane transport 8/580 219/18722 0.368475755061361 0.558217758354584 AKAP9/KCNN4/ITGB1/SLC12A9/SLC9A1/VAMP2/CAV1/YWHAE 8 GO:0002683 negative regulation of immune system process 15/580 434/18722 0.369303053766013 0.558217758354584 FBN1/GRN/CD46/DUSP1/GLI3/PRKDC/DPP4/DLG5/CDK6/MIF/CD55/GPX1/SERPINB9/HMGB1/PHPT1 15 GO:0002548 monocyte chemotaxis 3/580 70/18722 0.369615834027248 0.558217758354584 DUSP1/LGMN/HMGB1 3 GO:0003407 neural retina development 3/580 70/18722 0.369615834027248 0.558217758354584 ATP2B1/NAGLU/TFAP2A 3 GO:0045123 cellular extravasation 3/580 70/18722 0.369615834027248 0.558217758354584 ITGB1/ROCK1/JAM3 3 GO:0046578 regulation of Ras protein signal transduction 7/580 189/18722 0.369914796725987 0.558217758354584 ADGRG1/ITGB1/KANK1/MET/RASA1/STMN1/DYNLT1 7 GO:0006334 nucleosome assembly 5/580 129/18722 0.370401553878939 0.558217758354584 ATRX/NPM1/RSF1/HMGB2/DNAJC9 5 GO:0098813 nuclear chromosome segregation 10/580 281/18722 0.372866871156534 0.558217758354584 DYNC1H1/DUSP1/ATRX/CENPF/NIPBL/TPR/RAN/CDC42/ANAPC11/RAB11A 10 GO:0006664 glycolipid metabolic process 4/580 100/18722 0.375073602621566 0.558217758354584 HEXA/GPAA1/FUCA1/NEU1 4 GO:0046545 development of primary female sexual characteristics 4/580 100/18722 0.375073602621566 0.558217758354584 HSPA5/ADAMTS1/NR2F2/ARID5B 4 GO:0006040 amino sugar metabolic process 2/580 42/18722 0.37535844100875 0.558217758354584 EXTL2/MGAT1 2 GO:0009124 nucleoside monophosphate biosynthetic process 2/580 42/18722 0.37535844100875 0.558217758354584 DUT/TYMS 2 GO:0010591 regulation of lamellipodium assembly 2/580 42/18722 0.37535844100875 0.558217758354584 WASF2/CDC42 2 GO:0019692 deoxyribose phosphate metabolic process 2/580 42/18722 0.37535844100875 0.558217758354584 DUT/TYMS 2 GO:0030808 regulation of nucleotide biosynthetic process 2/580 42/18722 0.37535844100875 0.558217758354584 ENO1/TMSB4X 2 GO:0032689 negative regulation of interferon-gamma production 2/580 42/18722 0.37535844100875 0.558217758354584 DDIT3/HMGB1 2 GO:0033574 response to testosterone 2/580 42/18722 0.37535844100875 0.558217758354584 DUSP1/CSNK2B 2 GO:0045047 protein targeting to ER 2/580 42/18722 0.37535844100875 0.558217758354584 HSPA5/SEC62 2 GO:0051452 intracellular pH reduction 2/580 42/18722 0.37535844100875 0.558217758354584 GRN/ATP6AP2 2 GO:0055090 acylglycerol homeostasis 2/580 42/18722 0.37535844100875 0.558217758354584 HMGCR/XBP1 2 GO:0070328 triglyceride homeostasis 2/580 42/18722 0.37535844100875 0.558217758354584 HMGCR/XBP1 2 GO:1900274 regulation of phospholipase C activity 2/580 42/18722 0.37535844100875 0.558217758354584 EGFR/GNAQ 2 GO:2000404 regulation of T cell migration 2/580 42/18722 0.37535844100875 0.558217758354584 APP/RHOA 2 GO:0019439 aromatic compound catabolic process 16/580 467/18722 0.375926749892514 0.558217758354584 KCNQ1OT1/HSPA1A/ZFP36L1/TNRC6A/YBX1/ROCK1/NPM1/PUM1/FUS/MGAT1/DUT/HNRNPC/HNRNPD/CIRBP/CARHSP1/SERBP1 16 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/580 15/18722 0.376385914900016 0.558217758354584 RPL7 1 GO:0000478 endonucleolytic cleavage involved in rRNA processing 1/580 15/18722 0.376385914900016 0.558217758354584 RPS21 1 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/580 15/18722 0.376385914900016 0.558217758354584 RPS21 1 GO:0002070 epithelial cell maturation 1/580 15/18722 0.376385914900016 0.558217758354584 TYMS 1 GO:0002679 respiratory burst involved in defense response 1/580 15/18722 0.376385914900016 0.558217758354584 GRN 1 GO:0006089 lactate metabolic process 1/580 15/18722 0.376385914900016 0.558217758354584 LDHA 1 GO:0006268 DNA unwinding involved in DNA replication 1/580 15/18722 0.376385914900016 0.558217758354584 PURA 1 GO:0006271 DNA strand elongation involved in DNA replication 1/580 15/18722 0.376385914900016 0.558217758354584 PCNA 1 GO:0006878 cellular copper ion homeostasis 1/580 15/18722 0.376385914900016 0.558217758354584 APP 1 GO:0010763 positive regulation of fibroblast migration 1/580 15/18722 0.376385914900016 0.558217758354584 ITGB1 1 GO:0010832 negative regulation of myotube differentiation 1/580 15/18722 0.376385914900016 0.558217758354584 XBP1 1 GO:0010889 regulation of sequestering of triglyceride 1/580 15/18722 0.376385914900016 0.558217758354584 PLIN2 1 GO:0015697 quaternary ammonium group transport 1/580 15/18722 0.376385914900016 0.558217758354584 SLC38A2 1 GO:0019511 peptidyl-proline hydroxylation 1/580 15/18722 0.376385914900016 0.558217758354584 P4HB 1 GO:0021542 dentate gyrus development 1/580 15/18722 0.376385914900016 0.558217758354584 CDK6 1 GO:0023035 CD40 signaling pathway 1/580 15/18722 0.376385914900016 0.558217758354584 ITGB1 1 GO:0031269 pseudopodium assembly 1/580 15/18722 0.376385914900016 0.558217758354584 CDC42 1 GO:0032239 regulation of nucleobase-containing compound transport 1/580 15/18722 0.376385914900016 0.558217758354584 TPR 1 GO:0032488 Cdc42 protein signal transduction 1/580 15/18722 0.376385914900016 0.558217758354584 CDC42 1 GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 1/580 15/18722 0.376385914900016 0.558217758354584 ISL1 1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway 1/580 15/18722 0.376385914900016 0.558217758354584 ISL1 1 GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway 1/580 15/18722 0.376385914900016 0.558217758354584 CITED2 1 GO:0035493 SNARE complex assembly 1/580 15/18722 0.376385914900016 0.558217758354584 VAMP2 1 GO:0035627 ceramide transport 1/580 15/18722 0.376385914900016 0.558217758354584 PSAP 1 GO:0036124 histone H3-K9 trimethylation 1/580 15/18722 0.376385914900016 0.558217758354584 ATRX 1 GO:0036376 sodium ion export across plasma membrane 1/580 15/18722 0.376385914900016 0.558217758354584 SLC9A1 1 GO:0042976 activation of Janus kinase activity 1/580 15/18722 0.376385914900016 0.558217758354584 PRLR 1 GO:0043252 sodium-independent organic anion transport 1/580 15/18722 0.376385914900016 0.558217758354584 MFSD10 1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 1/580 15/18722 0.376385914900016 0.558217758354584 MIF 1 GO:0043584 nose development 1/580 15/18722 0.376385914900016 0.558217758354584 GLI3 1 GO:0044406 adhesion of symbiont to host 1/580 15/18722 0.376385914900016 0.558217758354584 CD81 1 GO:0044793 negative regulation by host of viral process 1/580 15/18722 0.376385914900016 0.558217758354584 EIF2AK4 1 GO:0045064 T-helper 2 cell differentiation 1/580 15/18722 0.376385914900016 0.558217758354584 PRKCZ 1 GO:0045346 regulation of MHC class II biosynthetic process 1/580 15/18722 0.376385914900016 0.558217758354584 XBP1 1 GO:0045725 positive regulation of glycogen biosynthetic process 1/580 15/18722 0.376385914900016 0.558217758354584 IGF2 1 GO:0045842 positive regulation of mitotic metaphase/anaphase transition 1/580 15/18722 0.376385914900016 0.558217758354584 ANAPC11 1 GO:0046184 aldehyde biosynthetic process 1/580 15/18722 0.376385914900016 0.558217758354584 TPI1 1 GO:0046459 short-chain fatty acid metabolic process 1/580 15/18722 0.376385914900016 0.558217758354584 ACSS1 1 GO:0048308 organelle inheritance 1/580 15/18722 0.376385914900016 0.558217758354584 CDK1 1 GO:0048313 Golgi inheritance 1/580 15/18722 0.376385914900016 0.558217758354584 CDK1 1 GO:0050746 regulation of lipoprotein metabolic process 1/580 15/18722 0.376385914900016 0.558217758354584 ITGAV 1 GO:0051127 positive regulation of actin nucleation 1/580 15/18722 0.376385914900016 0.558217758354584 WASF2 1 GO:0051290 protein heterotetramerization 1/580 15/18722 0.376385914900016 0.558217758354584 RRM2 1 GO:0051299 centrosome separation 1/580 15/18722 0.376385914900016 0.558217758354584 RANBP1 1 GO:0051791 medium-chain fatty acid metabolic process 1/580 15/18722 0.376385914900016 0.558217758354584 CROT 1 GO:0055012 ventricular cardiac muscle cell differentiation 1/580 15/18722 0.376385914900016 0.558217758354584 CDK1 1 GO:0060049 regulation of protein glycosylation 1/580 15/18722 0.376385914900016 0.558217758354584 TMEM59 1 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 1/580 15/18722 0.376385914900016 0.558217758354584 TNRC6A 1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum 1/580 15/18722 0.376385914900016 0.558217758354584 CD81 1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade 1/580 15/18722 0.376385914900016 0.558217758354584 SLC9A1 1 GO:0071474 cellular hyperosmotic response 1/580 15/18722 0.376385914900016 0.558217758354584 SLC2A1 1 GO:0071871 response to epinephrine 1/580 15/18722 0.376385914900016 0.558217758354584 SLC9A1 1 GO:0072044 collecting duct development 1/580 15/18722 0.376385914900016 0.558217758354584 DLG5 1 GO:0072075 metanephric mesenchyme development 1/580 15/18722 0.376385914900016 0.558217758354584 BMP7 1 GO:0090594 inflammatory response to wounding 1/580 15/18722 0.376385914900016 0.558217758354584 GRN 1 GO:0097468 programmed cell death in response to reactive oxygen species 1/580 15/18722 0.376385914900016 0.558217758354584 MET 1 GO:0099170 postsynaptic modulation of chemical synaptic transmission 1/580 15/18722 0.376385914900016 0.558217758354584 CDH1 1 GO:0106058 positive regulation of calcineurin-mediated signaling 1/580 15/18722 0.376385914900016 0.558217758354584 SLC9A1 1 GO:0150011 regulation of neuron projection arborization 1/580 15/18722 0.376385914900016 0.558217758354584 MACF1 1 GO:1900029 positive regulation of ruffle assembly 1/580 15/18722 0.376385914900016 0.558217758354584 PFN1 1 GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1/580 15/18722 0.376385914900016 0.558217758354584 ZFP36L1 1 GO:1901836 regulation of transcription of nucleolar large rRNA by RNA polymerase I 1/580 15/18722 0.376385914900016 0.558217758354584 NCL 1 GO:1901841 regulation of high voltage-gated calcium channel activity 1/580 15/18722 0.376385914900016 0.558217758354584 CALM1 1 GO:1901970 positive regulation of mitotic sister chromatid separation 1/580 15/18722 0.376385914900016 0.558217758354584 ANAPC11 1 GO:1905168 positive regulation of double-strand break repair via homologous recombination 1/580 15/18722 0.376385914900016 0.558217758354584 FUS 1 GO:1990822 basic amino acid transmembrane transport 1/580 15/18722 0.376385914900016 0.558217758354584 SLC38A9 1 GO:2000052 positive regulation of non-canonical Wnt signaling pathway 1/580 15/18722 0.376385914900016 0.558217758354584 GPC3 1 GO:2000104 negative regulation of DNA-dependent DNA replication 1/580 15/18722 0.376385914900016 0.558217758354584 GMNN 1 GO:2000345 regulation of hepatocyte proliferation 1/580 15/18722 0.376385914900016 0.558217758354584 XBP1 1 GO:0006282 regulation of DNA repair 5/580 130/18722 0.376571142601784 0.558314435524672 EGFR/PRKDC/FUS/HMGB1/PCNA 5 GO:0002228 natural killer cell mediated immunity 3/580 71/18722 0.378081295064554 0.560374793927737 CADM1/KIF5B/SERPINB9 3 GO:0051650 establishment of vesicle localization 6/580 161/18722 0.381800620119937 0.565652645535207 DYNC1H1/TRIP11/TMED9/KIF5B/PRKCZ/RAB11A 6 GO:0046394 carboxylic acid biosynthetic process 11/580 314/18722 0.382044116821511 0.565652645535207 MGST3/ACSS1/ILVBL/SLC27A2/HACD3/PTGES2/MIF/XBP1/DEGS1/ACADVL/PTGES3 11 GO:0051963 regulation of synapse assembly 4/580 101/18722 0.382128706143113 0.565652645535207 APP/TPBG/DLG5/EIF4G1 4 GO:1903509 liposaccharide metabolic process 4/580 101/18722 0.382128706143113 0.565652645535207 HEXA/GPAA1/FUCA1/NEU1 4 GO:0007059 chromosome segregation 12/580 346/18722 0.386324777349843 0.568537897903946 DYNC1H1/DUSP1/ATRX/CENPF/PUM1/NIPBL/TPR/RAN/CENPN/CDC42/ANAPC11/RAB11A 12 GO:0001709 cell fate determination 2/580 43/18722 0.386466025701909 0.568537897903946 ISL1/CDC42 2 GO:0002861 regulation of inflammatory response to antigenic stimulus 2/580 43/18722 0.386466025701909 0.568537897903946 CD81/GPX1 2 GO:0006284 base-excision repair 2/580 43/18722 0.386466025701909 0.568537897903946 HMGB1/PCNA 2 GO:0016266 O-glycan processing 2/580 43/18722 0.386466025701909 0.568537897903946 C1GALT1/GALNT11 2 GO:0021983 pituitary gland development 2/580 43/18722 0.386466025701909 0.568537897903946 CDH1/ISL1 2 GO:0033173 calcineurin-NFAT signaling cascade 2/580 43/18722 0.386466025701909 0.568537897903946 NFAT5/SLC9A1 2 GO:0035794 positive regulation of mitochondrial membrane permeability 2/580 43/18722 0.386466025701909 0.568537897903946 HSPA1A/SLC9A1 2 GO:0036230 granulocyte activation 2/580 43/18722 0.386466025701909 0.568537897903946 GRN/VAMP2 2 GO:0045776 negative regulation of blood pressure 2/580 43/18722 0.386466025701909 0.568537897903946 GJA5/ADRB1 2 GO:0046636 negative regulation of alpha-beta T cell activation 2/580 43/18722 0.386466025701909 0.568537897903946 GLI3/HMGB1 2 GO:0098815 modulation of excitatory postsynaptic potential 2/580 43/18722 0.386466025701909 0.568537897903946 APP/PRKCZ 2 GO:1901381 positive regulation of potassium ion transmembrane transport 2/580 43/18722 0.386466025701909 0.568537897903946 AKAP9/KCNN4 2 GO:1903793 positive regulation of anion transport 2/580 43/18722 0.386466025701909 0.568537897903946 TCAF1/ITGB1 2 GO:0014743 regulation of muscle hypertrophy 3/580 72/18722 0.386522647424699 0.568537897903946 SLC9A1/ROCK1/IL6ST 3 GO:0030032 lamellipodium assembly 3/580 72/18722 0.386522647424699 0.568537897903946 ITGB1/WASF2/CDC42 3 GO:0050709 negative regulation of protein secretion 3/580 72/18722 0.386522647424699 0.568537897903946 ERP29/HMGCR/FRMD4A 3 GO:0051057 positive regulation of small GTPase mediated signal transduction 3/580 72/18722 0.386522647424699 0.568537897903946 ITGAV/ADGRG1/DYNLT1 3 GO:0070227 lymphocyte apoptotic process 3/580 72/18722 0.386522647424699 0.568537897903946 SLC39A10/RPS6/GLI3 3 GO:1901880 negative regulation of protein depolymerization 3/580 72/18722 0.386522647424699 0.568537897903946 SPTAN1/SPTBN1/TRIOBP 3 GO:0002274 myeloid leukocyte activation 8/580 223/18722 0.387305945537138 0.569389718165909 GRN/JUND/APP/CTSC/VAMP2/MIF/HMGB1/DHRS2 8 GO:0021953 central nervous system neuron differentiation 6/580 162/18722 0.38734660681078 0.569389718165909 NRP2/SOX4/MYCBP2/ISL1/GLI3/LMO4 6 GO:0006839 mitochondrial transport 9/580 254/18722 0.388686691738828 0.571179084763756 LMAN1/HSPA1A/SLC9A1/SLC25A36/PMAIP1/LEPROT/VDAC1/DYNLT1/UBE2L3 9 GO:1902106 negative regulation of leukocyte differentiation 4/580 102/18722 0.38917486735 0.571715826925095 FBN1/GLI3/CDK6/HMGB1 4 GO:0016053 organic acid biosynthetic process 11/580 316/18722 0.389959107370651 0.571938179412355 MGST3/ACSS1/ILVBL/SLC27A2/HACD3/PTGES2/MIF/XBP1/DEGS1/ACADVL/PTGES3 11 GO:0002637 regulation of immunoglobulin production 3/580 73/18722 0.394936558115434 0.571938179412355 PRKDC/TFRC/XBP1 3 GO:0099518 vesicle cytoskeletal trafficking 3/580 73/18722 0.394936558115434 0.571938179412355 DYNC1H1/KIF5B/PRKCZ 3 GO:0009855 determination of bilateral symmetry 5/580 133/18722 0.395067878494409 0.571938179412355 FOLR1/DDIT3/TBX3/GALNT11/CITED2 5 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 5/580 133/18722 0.395067878494409 0.571938179412355 HSPA1A/CTSC/TMEM259/HECTD1/CAV1 5 GO:0002093 auditory receptor cell morphogenesis 1/580 16/18722 0.395720718415171 0.571938179412355 TRIOBP 1 GO:0002693 positive regulation of cellular extravasation 1/580 16/18722 0.395720718415171 0.571938179412355 JAM3 1 GO:0006004 fucose metabolic process 1/580 16/18722 0.395720718415171 0.571938179412355 FUCA1 1 GO:0006206 pyrimidine nucleobase metabolic process 1/580 16/18722 0.395720718415171 0.571938179412355 TYMS 1 GO:0006266 DNA ligation 1/580 16/18722 0.395720718415171 0.571938179412355 HMGB1 1 GO:0006349 regulation of gene expression by genetic imprinting 1/580 16/18722 0.395720718415171 0.571938179412355 IGF2 1 GO:0006544 glycine metabolic process 1/580 16/18722 0.395720718415171 0.571938179412355 GLDC 1 GO:0006857 oligopeptide transport 1/580 16/18722 0.395720718415171 0.571938179412355 GJA1 1 GO:0007635 chemosensory behavior 1/580 16/18722 0.395720718415171 0.571938179412355 TPBG 1 GO:0014819 regulation of skeletal muscle contraction 1/580 16/18722 0.395720718415171 0.571938179412355 GSTO1 1 GO:0016074 sno(s)RNA metabolic process 1/580 16/18722 0.395720718415171 0.571938179412355 FBL 1 GO:0016584 nucleosome positioning 1/580 16/18722 0.395720718415171 0.571938179412355 RSF1 1 GO:0021535 cell migration in hindbrain 1/580 16/18722 0.395720718415171 0.571938179412355 ITGB1 1 GO:0031268 pseudopodium organization 1/580 16/18722 0.395720718415171 0.571938179412355 CDC42 1 GO:0034116 positive regulation of heterotypic cell-cell adhesion 1/580 16/18722 0.395720718415171 0.571938179412355 BMP7 1 GO:0034138 toll-like receptor 3 signaling pathway 1/580 16/18722 0.395720718415171 0.571938179412355 CAV1 1 GO:0035970 peptidyl-threonine dephosphorylation 1/580 16/18722 0.395720718415171 0.571938179412355 DUSP1 1 GO:0043923 positive regulation by host of viral transcription 1/580 16/18722 0.395720718415171 0.571938179412355 JUN 1 GO:0045342 MHC class II biosynthetic process 1/580 16/18722 0.395720718415171 0.571938179412355 XBP1 1 GO:0045721 negative regulation of gluconeogenesis 1/580 16/18722 0.395720718415171 0.571938179412355 PGP 1 GO:0045722 positive regulation of gluconeogenesis 1/580 16/18722 0.395720718415171 0.571938179412355 DDB1 1 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate 1/580 16/18722 0.395720718415171 0.571938179412355 MPHOSPH8 1 GO:0050965 detection of temperature stimulus involved in sensory perception of pain 1/580 16/18722 0.395720718415171 0.571938179412355 NR2F6 1 GO:0051014 actin filament severing 1/580 16/18722 0.395720718415171 0.571938179412355 CFL1 1 GO:0055089 fatty acid homeostasis 1/580 16/18722 0.395720718415171 0.571938179412355 XBP1 1 GO:0060572 morphogenesis of an epithelial bud 1/580 16/18722 0.395720718415171 0.571938179412355 BMP7 1 GO:0061548 ganglion development 1/580 16/18722 0.395720718415171 0.571938179412355 NRP2 1 GO:0070242 thymocyte apoptotic process 1/580 16/18722 0.395720718415171 0.571938179412355 GLI3 1 GO:0071391 cellular response to estrogen stimulus 1/580 16/18722 0.395720718415171 0.571938179412355 SERPINB9 1 GO:0071639 positive regulation of monocyte chemotactic protein-1 production 1/580 16/18722 0.395720718415171 0.571938179412355 HMGB1 1 GO:0071732 cellular response to nitric oxide 1/580 16/18722 0.395720718415171 0.571938179412355 HNRNPD 1 GO:0072148 epithelial cell fate commitment 1/580 16/18722 0.395720718415171 0.571938179412355 NR2F2 1 GO:0080009 mRNA methylation 1/580 16/18722 0.395720718415171 0.571938179412355 ZC3H13 1 GO:0090336 positive regulation of brown fat cell differentiation 1/580 16/18722 0.395720718415171 0.571938179412355 BMP7 1 GO:0097284 hepatocyte apoptotic process 1/580 16/18722 0.395720718415171 0.571938179412355 KRT8 1 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration 1/580 16/18722 0.395720718415171 0.571938179412355 ATP2B1 1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway 1/580 16/18722 0.395720718415171 0.571938179412355 SEMA6A 1 GO:1901163 regulation of trophoblast cell migration 1/580 16/18722 0.395720718415171 0.571938179412355 GJA1 1 GO:1901201 regulation of extracellular matrix assembly 1/580 16/18722 0.395720718415171 0.571938179412355 DAG1 1 GO:1902101 positive regulation of metaphase/anaphase transition of cell cycle 1/580 16/18722 0.395720718415171 0.571938179412355 ANAPC11 1 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/580 16/18722 0.395720718415171 0.571938179412355 MIF 1 GO:1904683 regulation of metalloendopeptidase activity 1/580 16/18722 0.395720718415171 0.571938179412355 TIMP3 1 GO:1905906 regulation of amyloid fibril formation 1/580 16/18722 0.395720718415171 0.571938179412355 APP 1 GO:2000001 regulation of DNA damage checkpoint 1/580 16/18722 0.395720718415171 0.571938179412355 PPP1R10 1 GO:2000765 regulation of cytoplasmic translation 1/580 16/18722 0.395720718415171 0.571938179412355 PKM 1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining 1/580 16/18722 0.395720718415171 0.571938179412355 PRKDC 1 GO:2001212 regulation of vasculogenesis 1/580 16/18722 0.395720718415171 0.571938179412355 ADM 1 GO:0030004 cellular monovalent inorganic cation homeostasis 4/580 103/18722 0.396209974136089 0.572289624132593 GRN/ATP6AP1/SLC9A1/ATP6AP2 4 GO:0030148 sphingolipid biosynthetic process 4/580 103/18722 0.396209974136089 0.572289624132593 PLPP3/HACD3/ORMDL1/DEGS1 4 GO:0008037 cell recognition 8/580 225/18722 0.396737544201948 0.572873740479125 APP/SPESP1/ALDOA/BSG/CADM1/FOLR1/RTN4/CD81 8 GO:0006775 fat-soluble vitamin metabolic process 2/580 44/18722 0.397486181763119 0.573242862443493 LRP2/LGMN 2 GO:0042269 regulation of natural killer cell mediated cytotoxicity 2/580 44/18722 0.397486181763119 0.573242862443493 CADM1/SERPINB9 2 GO:0046006 regulation of activated T cell proliferation 2/580 44/18722 0.397486181763119 0.573242862443493 HMGB1/IGF2 2 GO:0048066 developmental pigmentation 2/580 44/18722 0.397486181763119 0.573242862443493 GLI3/ATP6AP2 2 GO:0002700 regulation of production of molecular mediator of immune response 6/580 164/18722 0.398436414005606 0.574257130938975 PRKDC/TFRC/CD81/XBP1/CD55/PRKCZ 6 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 6/580 164/18722 0.398436414005606 0.574257130938975 UFL1/RPL23/HSPA1A/HECTD1/CAV1/EIF3H 6 GO:0002705 positive regulation of leukocyte mediated immunity 5/580 134/18722 0.401224514615101 0.577559646386517 CADM1/TFRC/CD81/CD55/PRKCZ 5 GO:0009799 specification of symmetry 5/580 134/18722 0.401224514615101 0.577559646386517 FOLR1/DDIT3/TBX3/GALNT11/CITED2 5 GO:0032147 activation of protein kinase activity 5/580 134/18722 0.401224514615101 0.577559646386517 PPIA/PRLR/TXN/PRKCZ/HMGB1 5 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 5/580 134/18722 0.401224514615101 0.577559646386517 UFL1/HSPA1A/HECTD1/CAV1/EIF3H 5 GO:0002703 regulation of leukocyte mediated immunity 8/580 226/18722 0.401455052290177 0.57771270055743 CD46/CADM1/TFRC/CD81/CD55/PRKCZ/SERPINB9/HMGB1 8 GO:0014896 muscle hypertrophy 4/580 104/18722 0.403231965902223 0.579499687011826 SLC9A1/ROCK1/IL6ST/CYBA 4 GO:0032963 collagen metabolic process 4/580 104/18722 0.403231965902223 0.579499687011826 CTSL/ITGB1/SERPINH1/MMP15 4 GO:0009201 ribonucleoside triphosphate biosynthetic process 3/580 74/18722 0.403319820868046 0.579499687011826 ALDOA/ENO1/TMSB4X 3 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 3/580 74/18722 0.403319820868046 0.579499687011826 UFL1/ISL1/RHOA 3 GO:0051881 regulation of mitochondrial membrane potential 3/580 74/18722 0.403319820868046 0.579499687011826 SLC25A36/PMAIP1/ARL6IP5 3 GO:0007018 microtubule-based movement 13/580 382/18722 0.404530128966591 0.581059181539103 ARMCX3/DYNC1H1/APP/KTN1/DST/PURA/KIF5B/ARHGAP21/HSPA8/PRKCZ/DYNLRB1/CDC42/DYNLT1 13 GO:0071674 mononuclear cell migration 7/580 196/18722 0.405464710072039 0.582221786522091 APP/PLEC/DUSP1/LGMN/RHOA/HMGB1/CDC42 7 GO:0016042 lipid catabolic process 11/580 320/18722 0.405821695467481 0.582554538771375 LRP1/HEXA/ILVBL/SLC27A2/FUCA1/NEU1/CROT/ECHDC2/ACADVL/HADHA/YWHAH 11 GO:0002687 positive regulation of leukocyte migration 5/580 135/18722 0.407374276737575 0.583426083686088 APP/JAM3/LGMN/RHOA/HMGB1 5 GO:0042157 lipoprotein metabolic process 5/580 135/18722 0.407374276737575 0.583426083686088 LRP1/CTSD/ITGAV/GPAA1/NOTUM 5 GO:0002920 regulation of humoral immune response 2/580 45/18722 0.408413665517351 0.583426083686088 CD46/CD55 2 GO:0003009 skeletal muscle contraction 2/580 45/18722 0.408413665517351 0.583426083686088 GAA/GSTO1 2 GO:0006903 vesicle targeting 2/580 45/18722 0.408413665517351 0.583426083686088 TRIP11/TMED9 2 GO:0022602 ovulation cycle process 2/580 45/18722 0.408413665517351 0.583426083686088 HSPA5/ADAMTS1 2 GO:0048546 digestive tract morphogenesis 2/580 45/18722 0.408413665517351 0.583426083686088 GLI3/NIPBL 2 GO:0060421 positive regulation of heart growth 2/580 45/18722 0.408413665517351 0.583426083686088 TGFBR3/CDK1 2 GO:0085029 extracellular matrix assembly 2/580 45/18722 0.408413665517351 0.583426083686088 LAMB1/DAG1 2 GO:0098534 centriole assembly 2/580 45/18722 0.408413665517351 0.583426083686088 NPM1/E2F4 2 GO:1901985 positive regulation of protein acetylation 2/580 45/18722 0.408413665517351 0.583426083686088 SOX4/ISL1 2 GO:2000273 positive regulation of signaling receptor activity 2/580 45/18722 0.408413665517351 0.583426083686088 ITGB1/NCOA3 2 GO:0071103 DNA conformation change 10/580 290/18722 0.410398708203336 0.583426083686088 PURA/ATRX/NPM1/RSF1/HNRNPA2B1/HMGB1/HMGB3/CDK1/HMGB2/DNAJC9 10 GO:0002292 T cell differentiation involved in immune response 3/580 75/18722 0.411669354664477 0.583426083686088 CD46/PRKCZ/HMGB1 3 GO:0006094 gluconeogenesis 3/580 75/18722 0.411669354664477 0.583426083686088 DDB1/TPI1/PGP 3 GO:0006278 RNA-dependent DNA biosynthetic process 3/580 75/18722 0.411669354664477 0.583426083686088 HNRNPA1/PTGES3/HNRNPC 3 GO:0051453 regulation of intracellular pH 3/580 75/18722 0.411669354664477 0.583426083686088 GRN/SLC9A1/ATP6AP2 3 GO:1903363 negative regulation of cellular protein catabolic process 3/580 75/18722 0.411669354664477 0.583426083686088 RPL23/EIF3H/ATRAID 3 GO:0002031 G protein-coupled receptor internalization 1/580 17/18722 0.414457058804308 0.583426083686088 ADM 1 GO:0003184 pulmonary valve morphogenesis 1/580 17/18722 0.414457058804308 0.583426083686088 GJA5 1 GO:0006474 N-terminal protein amino acid acetylation 1/580 17/18722 0.414457058804308 0.583426083686088 SOX4 1 GO:0006901 vesicle coating 1/580 17/18722 0.414457058804308 0.583426083686088 TMED9 1 GO:0007351 tripartite regional subdivision 1/580 17/18722 0.414457058804308 0.583426083686088 TBX3 1 GO:0007379 segment specification 1/580 17/18722 0.414457058804308 0.583426083686088 IRX2 1 GO:0008595 anterior/posterior axis specification, embryo 1/580 17/18722 0.414457058804308 0.583426083686088 TBX3 1 GO:0009812 flavonoid metabolic process 1/580 17/18722 0.414457058804308 0.583426083686088 POR 1 GO:0010470 regulation of gastrulation 1/580 17/18722 0.414457058804308 0.583426083686088 DAG1 1 GO:0015867 ATP transport 1/580 17/18722 0.414457058804308 0.583426083686088 GJA1 1 GO:0021513 spinal cord dorsal/ventral patterning 1/580 17/18722 0.414457058804308 0.583426083686088 GLI3 1 GO:0021924 cell proliferation in external granule layer 1/580 17/18722 0.414457058804308 0.583426083686088 SLC6A4 1 GO:0021930 cerebellar granule cell precursor proliferation 1/580 17/18722 0.414457058804308 0.583426083686088 SLC6A4 1 GO:0030322 stabilization of membrane potential 1/580 17/18722 0.414457058804308 0.583426083686088 KCNN4 1 GO:0032048 cardiolipin metabolic process 1/580 17/18722 0.414457058804308 0.583426083686088 HADHA 1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway 1/580 17/18722 0.414457058804308 0.583426083686088 LEPROT 1 GO:0032604 granulocyte macrophage colony-stimulating factor production 1/580 17/18722 0.414457058804308 0.583426083686088 ISL1 1 GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 1/580 17/18722 0.414457058804308 0.583426083686088 ISL1 1 GO:0035518 histone H2A monoubiquitination 1/580 17/18722 0.414457058804308 0.583426083686088 DDB1 1 GO:0035729 cellular response to hepatocyte growth factor stimulus 1/580 17/18722 0.414457058804308 0.583426083686088 LGMN 1 GO:0035855 megakaryocyte development 1/580 17/18722 0.414457058804308 0.583426083686088 WASF2 1 GO:0038065 collagen-activated signaling pathway 1/580 17/18722 0.414457058804308 0.583426083686088 COL4A2 1 GO:0042339 keratan sulfate metabolic process 1/580 17/18722 0.414457058804308 0.583426083686088 GNS 1 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 1/580 17/18722 0.414457058804308 0.583426083686088 CAV1 1 GO:0042953 lipoprotein transport 1/580 17/18722 0.414457058804308 0.583426083686088 LRP1 1 GO:0043968 histone H2A acetylation 1/580 17/18722 0.414457058804308 0.583426083686088 MORF4L2 1 GO:0045591 positive regulation of regulatory T cell differentiation 1/580 17/18722 0.414457058804308 0.583426083686088 CD46 1 GO:0045815 positive regulation of gene expression, epigenetic 1/580 17/18722 0.414457058804308 0.583426083686088 SERTAD1 1 GO:0051580 regulation of neurotransmitter uptake 1/580 17/18722 0.414457058804308 0.583426083686088 ITGB1 1 GO:0051797 regulation of hair follicle development 1/580 17/18722 0.414457058804308 0.583426083686088 FERMT1 1 GO:0055064 chloride ion homeostasis 1/580 17/18722 0.414457058804308 0.583426083686088 SLC12A9 1 GO:0055083 monovalent inorganic anion homeostasis 1/580 17/18722 0.414457058804308 0.583426083686088 SLC12A9 1 GO:0060033 anatomical structure regression 1/580 17/18722 0.414457058804308 0.583426083686088 LRP5 1 GO:0060263 regulation of respiratory burst 1/580 17/18722 0.414457058804308 0.583426083686088 GRN 1 GO:0061298 retina vasculature development in camera-type eye 1/580 17/18722 0.414457058804308 0.583426083686088 LRP5 1 GO:0070593 dendrite self-avoidance 1/580 17/18722 0.414457058804308 0.583426083686088 BSG 1 GO:0071371 cellular response to gonadotropin stimulus 1/580 17/18722 0.414457058804308 0.583426083686088 POR 1 GO:0097067 cellular response to thyroid hormone stimulus 1/580 17/18722 0.414457058804308 0.583426083686088 CTSL 1 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity 1/580 17/18722 0.414457058804308 0.583426083686088 AKAP9 1 GO:1900034 regulation of cellular response to heat 1/580 17/18722 0.414457058804308 0.583426083686088 DNAJB1 1 GO:1901550 regulation of endothelial cell development 1/580 17/18722 0.414457058804308 0.583426083686088 ROCK1 1 GO:1901569 fatty acid derivative catabolic process 1/580 17/18722 0.414457058804308 0.583426083686088 HPGD 1 GO:1903140 regulation of establishment of endothelial barrier 1/580 17/18722 0.414457058804308 0.583426083686088 ROCK1 1 GO:1903358 regulation of Golgi organization 1/580 17/18722 0.414457058804308 0.583426083686088 AKAP9 1 GO:1903830 magnesium ion transmembrane transport 1/580 17/18722 0.414457058804308 0.583426083686088 TUSC3 1 GO:1904355 positive regulation of telomere capping 1/580 17/18722 0.414457058804308 0.583426083686088 HNRNPD 1 GO:0034728 nucleosome organization 6/580 167/18722 0.415049534378751 0.584083323569008 BPTF/ATRX/NPM1/RSF1/HMGB2/DNAJC9 6 GO:0019882 antigen processing and presentation 4/580 106/18722 0.417228621307396 0.586617387454866 CTSL/CTSD/CTSV/LGMN 4 GO:0071887 leukocyte apoptotic process 4/580 106/18722 0.417228621307396 0.586617387454866 CTSL/SLC39A10/RPS6/GLI3 4 GO:1903707 negative regulation of hemopoiesis 4/580 106/18722 0.417228621307396 0.586617387454866 FBN1/GLI3/CDK6/HMGB1 4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 2/580 46/18722 0.419243640865073 0.588383275094585 TENM3/CADM1 2 GO:0031018 endocrine pancreas development 2/580 46/18722 0.419243640865073 0.588383275094585 SOX4/CDK6 2 GO:0032924 activin receptor signaling pathway 2/580 46/18722 0.419243640865073 0.588383275094585 CITED2/CSNK2B 2 GO:0034198 cellular response to amino acid starvation 2/580 46/18722 0.419243640865073 0.588383275094585 SLC38A2/EIF2AK4 2 GO:0070828 heterochromatin organization 2/580 46/18722 0.419243640865073 0.588383275094585 TPR/MPHOSPH8 2 GO:0072599 establishment of protein localization to endoplasmic reticulum 2/580 46/18722 0.419243640865073 0.588383275094585 HSPA5/SEC62 2 GO:0001937 negative regulation of endothelial cell proliferation 3/580 76/18722 0.419982202136811 0.588531853612025 GJA1/NR2F2/CAV1 3 GO:0006305 DNA alkylation 3/580 76/18722 0.419982202136811 0.588531853612025 FOS/ATRX/MPHOSPH8 3 GO:0006306 DNA methylation 3/580 76/18722 0.419982202136811 0.588531853612025 FOS/ATRX/MPHOSPH8 3 GO:0021536 diencephalon development 3/580 76/18722 0.419982202136811 0.588531853612025 NRP2/CDH1/ISL1 3 GO:2000379 positive regulation of reactive oxygen species metabolic process 3/580 76/18722 0.419982202136811 0.588531853612025 EGFR/GNAI2/CYBA 3 GO:0045333 cellular respiration 8/580 230/18722 0.420320720996533 0.588828817275565 COX6A1/PLEC/IL10RB/NDUFB9/RHOA/UQCRH/COX8C/CDK1 8 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6/580 168/18722 0.42057727372166 0.588994662184862 CD46/TFRC/CD81/CD55/PRKCZ/HMGB1 6 GO:0006323 DNA packaging 7/580 199/18722 0.420692381805657 0.588994662184862 ATRX/NPM1/RSF1/HMGB1/CDK1/HMGB2/DNAJC9 7 GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 4/580 107/18722 0.424199423714213 0.593010627357177 TFRC/CD81/CD55/PRKCZ 4 GO:0008637 apoptotic mitochondrial changes 4/580 107/18722 0.424199423714213 0.593010627357177 JUN/HSPA1A/PMAIP1/GPX1 4 GO:0032526 response to retinoic acid 4/580 107/18722 0.424199423714213 0.593010627357177 SERPINF1/DUSP1/GJA1/SLC6A4 4 GO:0071868 cellular response to monoamine stimulus 4/580 107/18722 0.424199423714213 0.593010627357177 APP/NCSTN/SLC9A1/ID1 4 GO:0071870 cellular response to catecholamine stimulus 4/580 107/18722 0.424199423714213 0.593010627357177 APP/NCSTN/SLC9A1/ID1 4 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 5/580 138/18722 0.425768425748871 0.593010627357177 HSPA5/MYCBP2/NPM1/CAV1/UBE2L3 5 GO:0001754 eye photoreceptor cell differentiation 2/580 47/18722 0.429971659137819 0.593010627357177 NAGLU/TUG1 2 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 2/580 47/18722 0.429971659137819 0.593010627357177 HSPA1A/SPPL2A 2 GO:0031641 regulation of myelination 2/580 47/18722 0.429971659137819 0.593010627357177 DAG1/CTSC 2 GO:0043114 regulation of vascular permeability 2/580 47/18722 0.429971659137819 0.593010627357177 PLEC/ADM 2 GO:0045332 phospholipid translocation 2/580 47/18722 0.429971659137819 0.593010627357177 KCNN4/ATP10D 2 GO:0045581 negative regulation of T cell differentiation 2/580 47/18722 0.429971659137819 0.593010627357177 GLI3/HMGB1 2 GO:0045747 positive regulation of Notch signaling pathway 2/580 47/18722 0.429971659137819 0.593010627357177 AAK1/IL6ST 2 GO:0045911 positive regulation of DNA recombination 2/580 47/18722 0.429971659137819 0.593010627357177 TFRC/FUS 2 GO:0050798 activated T cell proliferation 2/580 47/18722 0.429971659137819 0.593010627357177 HMGB1/IGF2 2 GO:0072583 clathrin-dependent endocytosis 2/580 47/18722 0.429971659137819 0.593010627357177 AAK1/CANX 2 GO:0097028 dendritic cell differentiation 2/580 47/18722 0.429971659137819 0.593010627357177 HMGB1/DHRS2 2 GO:0097300 programmed necrotic cell death 2/580 47/18722 0.429971659137819 0.593010627357177 CAV1/PYGL 2 GO:0101023 vascular endothelial cell proliferation 2/580 47/18722 0.429971659137819 0.593010627357177 HMGB1/IGF2 2 GO:1905562 regulation of vascular endothelial cell proliferation 2/580 47/18722 0.429971659137819 0.593010627357177 HMGB1/IGF2 2 GO:0022037 metencephalon development 4/580 108/18722 0.431149388896331 0.593010627357177 HSPA5/NAGLU/NCSTN/HNRNPD 4 GO:0002643 regulation of tolerance induction 1/580 18/18722 0.432613429073942 0.593010627357177 HMGB1 1 GO:0003417 growth plate cartilage development 1/580 18/18722 0.432613429073942 0.593010627357177 POR 1 GO:0006085 acetyl-CoA biosynthetic process 1/580 18/18722 0.432613429073942 0.593010627357177 ACSS1 1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process 1/580 18/18722 0.432613429073942 0.593010627357177 MPDU1 1 GO:0010663 positive regulation of striated muscle cell apoptotic process 1/580 18/18722 0.432613429073942 0.593010627357177 HMGCR 1 GO:0010666 positive regulation of cardiac muscle cell apoptotic process 1/580 18/18722 0.432613429073942 0.593010627357177 HMGCR 1 GO:0015693 magnesium ion transport 1/580 18/18722 0.432613429073942 0.593010627357177 TUSC3 1 GO:0019896 axonal transport of mitochondrion 1/580 18/18722 0.432613429073942 0.593010627357177 ARMCX3 1 GO:0021511 spinal cord patterning 1/580 18/18722 0.432613429073942 0.593010627357177 GLI3 1 GO:0021534 cell proliferation in hindbrain 1/580 18/18722 0.432613429073942 0.593010627357177 SLC6A4 1 GO:0030730 sequestering of triglyceride 1/580 18/18722 0.432613429073942 0.593010627357177 PLIN2 1 GO:0031643 positive regulation of myelination 1/580 18/18722 0.432613429073942 0.593010627357177 DAG1 1 GO:0031649 heat generation 1/580 18/18722 0.432613429073942 0.593010627357177 ADRB1 1 GO:0032634 interleukin-5 production 1/580 18/18722 0.432613429073942 0.593010627357177 PRKCZ 1 GO:0032674 regulation of interleukin-5 production 1/580 18/18722 0.432613429073942 0.593010627357177 PRKCZ 1 GO:0032769 negative regulation of monooxygenase activity 1/580 18/18722 0.432613429073942 0.593010627357177 CAV1 1 GO:0033189 response to vitamin A 1/580 18/18722 0.432613429073942 0.593010627357177 TYMS 1 GO:0035372 protein localization to microtubule 1/580 18/18722 0.432613429073942 0.593010627357177 DIAPH1 1 GO:0036507 protein demannosylation 1/580 18/18722 0.432613429073942 0.593010627357177 MAN1A2 1 GO:0036508 protein alpha-1,2-demannosylation 1/580 18/18722 0.432613429073942 0.593010627357177 MAN1A2 1 GO:0042136 neurotransmitter biosynthetic process 1/580 18/18722 0.432613429073942 0.593010627357177 SLC6A4 1 GO:0042693 muscle cell fate commitment 1/580 18/18722 0.432613429073942 0.593010627357177 TBX3 1 GO:0042790 nucleolar large rRNA transcription by RNA polymerase I 1/580 18/18722 0.432613429073942 0.593010627357177 NCL 1 GO:0043116 negative regulation of vascular permeability 1/580 18/18722 0.432613429073942 0.593010627357177 ADM 1 GO:0044872 lipoprotein localization 1/580 18/18722 0.432613429073942 0.593010627357177 LRP1 1 GO:0045187 regulation of circadian sleep/wake cycle, sleep 1/580 18/18722 0.432613429073942 0.593010627357177 ADRB1 1 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 1/580 18/18722 0.432613429073942 0.593010627357177 SERPINB9 1 GO:0050665 hydrogen peroxide biosynthetic process 1/580 18/18722 0.432613429073942 0.593010627357177 CYBA 1 GO:0051447 negative regulation of meiotic cell cycle 1/580 18/18722 0.432613429073942 0.593010627357177 DUSP1 1 GO:0051895 negative regulation of focal adhesion assembly 1/580 18/18722 0.432613429073942 0.593010627357177 LRP1 1 GO:0055070 copper ion homeostasis 1/580 18/18722 0.432613429073942 0.593010627357177 APP 1 GO:0060192 negative regulation of lipase activity 1/580 18/18722 0.432613429073942 0.593010627357177 POR 1 GO:0060546 negative regulation of necroptotic process 1/580 18/18722 0.432613429073942 0.593010627357177 CAV1 1 GO:0060716 labyrinthine layer blood vessel development 1/580 18/18722 0.432613429073942 0.593010627357177 JUNB 1 GO:0071318 cellular response to ATP 1/580 18/18722 0.432613429073942 0.593010627357177 HSP90B1 1 GO:0071360 cellular response to exogenous dsRNA 1/580 18/18722 0.432613429073942 0.593010627357177 CAV1 1 GO:0071786 endoplasmic reticulum tubular network organization 1/580 18/18722 0.432613429073942 0.593010627357177 RTN4 1 GO:0071800 podosome assembly 1/580 18/18722 0.432613429073942 0.593010627357177 RHOA 1 GO:0072079 nephron tubule formation 1/580 18/18722 0.432613429073942 0.593010627357177 IRX2 1 GO:0072234 metanephric nephron tubule development 1/580 18/18722 0.432613429073942 0.593010627357177 LGR4 1 GO:0097094 craniofacial suture morphogenesis 1/580 18/18722 0.432613429073942 0.593010627357177 GLI3 1 GO:0097709 connective tissue replacement 1/580 18/18722 0.432613429073942 0.593010627357177 ROCK1 1 GO:0150078 positive regulation of neuroinflammatory response 1/580 18/18722 0.432613429073942 0.593010627357177 CTSC 1 GO:0150079 negative regulation of neuroinflammatory response 1/580 18/18722 0.432613429073942 0.593010627357177 GRN 1 GO:0150118 negative regulation of cell-substrate junction organization 1/580 18/18722 0.432613429073942 0.593010627357177 LRP1 1 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1/580 18/18722 0.432613429073942 0.593010627357177 ZFP36L1 1 GO:1902001 fatty acid transmembrane transport 1/580 18/18722 0.432613429073942 0.593010627357177 SLC2A1 1 GO:1902170 cellular response to reactive nitrogen species 1/580 18/18722 0.432613429073942 0.593010627357177 HNRNPD 1 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus 1/580 18/18722 0.432613429073942 0.593010627357177 SEMA6A 1 GO:1905820 positive regulation of chromosome separation 1/580 18/18722 0.432613429073942 0.593010627357177 ANAPC11 1 GO:0019319 hexose biosynthetic process 3/580 78/18722 0.436486616489193 0.59743945064486 DDB1/TPI1/PGP 3 GO:0032371 regulation of sterol transport 3/580 78/18722 0.436486616489193 0.59743945064486 LRP1/CAV1/NFKBIA 3 GO:0032374 regulation of cholesterol transport 3/580 78/18722 0.436486616489193 0.59743945064486 LRP1/CAV1/NFKBIA 3 GO:0035050 embryonic heart tube development 3/580 78/18722 0.436486616489193 0.59743945064486 FOLR1/TBX3/CITED2 3 GO:0043537 negative regulation of blood vessel endothelial cell migration 3/580 78/18722 0.436486616489193 0.59743945064486 RHOA/HMGB1/CSNK2B 3 GO:0046890 regulation of lipid biosynthetic process 6/580 171/18722 0.437116339649634 0.597949439914837 EGR1/SF1/ADM/POR/ORMDL1/ACADVL 6 GO:0051048 negative regulation of secretion 6/580 171/18722 0.437116339649634 0.597949439914837 ERP29/GJA1/ERBB3/HMGCR/FRMD4A/GNAI2 6 GO:0007292 female gamete generation 5/580 140/18722 0.437971820852265 0.598591518890356 LGR5/RPS6/ADAMTS1/ASPM/HPGD 5 GO:0015748 organophosphate ester transport 5/580 140/18722 0.437971820852265 0.598591518890356 KCNN4/GJA1/SLC19A1/SLC25A36/ATP10D 5 GO:0046165 alcohol biosynthetic process 5/580 140/18722 0.437971820852265 0.598591518890356 DHCR24/ISYNA1/HMGCR/POR/PGP 5 GO:0002715 regulation of natural killer cell mediated immunity 2/580 48/18722 0.44059363980722 0.600762538476511 CADM1/SERPINB9 2 GO:0006111 regulation of gluconeogenesis 2/580 48/18722 0.44059363980722 0.600762538476511 DDB1/PGP 2 GO:0042908 xenobiotic transport 2/580 48/18722 0.44059363980722 0.600762538476511 SLC2A1/GJA1 2 GO:0090199 regulation of release of cytochrome c from mitochondria 2/580 48/18722 0.44059363980722 0.600762538476511 PMAIP1/GPX1 2 GO:0090311 regulation of protein deacetylation 2/580 48/18722 0.44059363980722 0.600762538476511 KDM5A/NIPBL 2 GO:0097720 calcineurin-mediated signaling 2/580 48/18722 0.44059363980722 0.600762538476511 NFAT5/SLC9A1 2 GO:1902003 regulation of amyloid-beta formation 2/580 48/18722 0.44059363980722 0.600762538476511 ROCK1/RTN4 2 GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 2/580 48/18722 0.44059363980722 0.600762538476511 RPL23/EIF3H 2 GO:0016571 histone methylation 5/580 141/18722 0.444051823745174 0.60220818533796 ATRX/KMT2C/BRD4/NSD1/FBL 5 GO:0034341 response to interferon-gamma 5/580 141/18722 0.444051823745174 0.60220818533796 GAPDH/RPL13A/KIF5B/ACTG1/CDC42 5 GO:0050921 positive regulation of chemotaxis 5/580 141/18722 0.444051823745174 0.60220818533796 MET/TPBG/TMSB4X/LGMN/HMGB1 5 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 3/580 79/18722 0.444672870933036 0.60220818533796 ERBB3/IGF1R/MYDGF 3 GO:1901184 regulation of ERBB signaling pathway 3/580 79/18722 0.444672870933036 0.60220818533796 EGFR/RTN4/LGMN 3 GO:0009408 response to heat 4/580 110/18722 0.444979660509033 0.60220818533796 HSPA1A/TPR/DNAJB1/YWHAE 4 GO:1905954 positive regulation of lipid localization 4/580 110/18722 0.444979660509033 0.60220818533796 LRP1/CAV1/PLIN2/NFKBIA 4 GO:0010469 regulation of signaling receptor activity 6/580 173/18722 0.448095772441692 0.60220818533796 AKAP9/APP/ITGB1/LRPAP1/NCOA3/PHLDA2 6 GO:0046467 membrane lipid biosynthetic process 5/580 142/18722 0.450115702287085 0.60220818533796 GPAA1/PLPP3/HACD3/ORMDL1/DEGS1 5 GO:0000028 ribosomal small subunit assembly 1/580 19/18722 0.450207751739527 0.60220818533796 PRKDC 1 GO:0002716 negative regulation of natural killer cell mediated immunity 1/580 19/18722 0.450207751739527 0.60220818533796 SERPINB9 1 GO:0002902 regulation of B cell apoptotic process 1/580 19/18722 0.450207751739527 0.60220818533796 SLC39A10 1 GO:0003085 negative regulation of systemic arterial blood pressure 1/580 19/18722 0.450207751739527 0.60220818533796 ADRB1 1 GO:0006044 N-acetylglucosamine metabolic process 1/580 19/18722 0.450207751739527 0.60220818533796 EXTL2 1 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process 1/580 19/18722 0.450207751739527 0.60220818533796 MPDU1 1 GO:0006670 sphingosine metabolic process 1/580 19/18722 0.450207751739527 0.60220818533796 PLPP3 1 GO:0006743 ubiquinone metabolic process 1/580 19/18722 0.450207751739527 0.60220818533796 HMGCR 1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 1/580 19/18722 0.450207751739527 0.60220818533796 SOX4 1 GO:0007603 phototransduction, visible light 1/580 19/18722 0.450207751739527 0.60220818533796 GNAQ 1 GO:0008356 asymmetric cell division 1/580 19/18722 0.450207751739527 0.60220818533796 ASPM 1 GO:0009081 branched-chain amino acid metabolic process 1/580 19/18722 0.450207751739527 0.60220818533796 ILVBL 1 GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process 1/580 19/18722 0.450207751739527 0.60220818533796 TYMS 1 GO:0009223 pyrimidine deoxyribonucleotide catabolic process 1/580 19/18722 0.450207751739527 0.60220818533796 DUT 1 GO:0010002 cardioblast differentiation 1/580 19/18722 0.450207751739527 0.60220818533796 ISL1 1 GO:0010738 regulation of protein kinase A signaling 1/580 19/18722 0.450207751739527 0.60220818533796 MIF 1 GO:0015802 basic amino acid transport 1/580 19/18722 0.450207751739527 0.60220818533796 SLC38A9 1 GO:0019373 epoxygenase P450 pathway 1/580 19/18722 0.450207751739527 0.60220818533796 CYP2J2 1 GO:0030220 platelet formation 1/580 19/18722 0.450207751739527 0.60220818533796 PRKDC 1 GO:0031065 positive regulation of histone deacetylation 1/580 19/18722 0.450207751739527 0.60220818533796 NIPBL 1 GO:0031290 retinal ganglion cell axon guidance 1/580 19/18722 0.450207751739527 0.60220818533796 ISL1 1 GO:0032616 interleukin-13 production 1/580 19/18722 0.450207751739527 0.60220818533796 PRKCZ 1 GO:0032656 regulation of interleukin-13 production 1/580 19/18722 0.450207751739527 0.60220818533796 PRKCZ 1 GO:0034501 protein localization to kinetochore 1/580 19/18722 0.450207751739527 0.60220818533796 CDK1 1 GO:0035313 wound healing, spreading of epidermal cells 1/580 19/18722 0.450207751739527 0.60220818533796 FERMT1 1 GO:0035728 response to hepatocyte growth factor 1/580 19/18722 0.450207751739527 0.60220818533796 LGMN 1 GO:0036344 platelet morphogenesis 1/580 19/18722 0.450207751739527 0.60220818533796 PRKDC 1 GO:0038092 nodal signaling pathway 1/580 19/18722 0.450207751739527 0.60220818533796 CITED2 1 GO:0042474 middle ear morphogenesis 1/580 19/18722 0.450207751739527 0.60220818533796 NAGLU 1 GO:0043031 negative regulation of macrophage activation 1/580 19/18722 0.450207751739527 0.60220818533796 GRN 1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate 1/580 19/18722 0.450207751739527 0.60220818533796 MPHOSPH8 1 GO:0045603 positive regulation of endothelial cell differentiation 1/580 19/18722 0.450207751739527 0.60220818533796 BTG1 1 GO:0045618 positive regulation of keratinocyte differentiation 1/580 19/18722 0.450207751739527 0.60220818533796 NCOA3 1 GO:0045821 positive regulation of glycolytic process 1/580 19/18722 0.450207751739527 0.60220818533796 APP 1 GO:0046653 tetrahydrofolate metabolic process 1/580 19/18722 0.450207751739527 0.60220818533796 TYMS 1 GO:0046782 regulation of viral transcription 1/580 19/18722 0.450207751739527 0.60220818533796 RSF1 1 GO:0050961 detection of temperature stimulus involved in sensory perception 1/580 19/18722 0.450207751739527 0.60220818533796 NR2F6 1 GO:0051546 keratinocyte migration 1/580 19/18722 0.450207751739527 0.60220818533796 FERMT1 1 GO:0051957 positive regulation of amino acid transport 1/580 19/18722 0.450207751739527 0.60220818533796 ITGB1 1 GO:0060039 pericardium development 1/580 19/18722 0.450207751739527 0.60220818533796 BMP7 1 GO:0060065 uterus development 1/580 19/18722 0.450207751739527 0.60220818533796 NIPBL 1 GO:0060216 definitive hemopoiesis 1/580 19/18722 0.450207751739527 0.60220818533796 TGFBR3 1 GO:0062099 negative regulation of programmed necrotic cell death 1/580 19/18722 0.450207751739527 0.60220818533796 CAV1 1 GO:0072074 kidney mesenchyme development 1/580 19/18722 0.450207751739527 0.60220818533796 BMP7 1 GO:0097501 stress response to metal ion 1/580 19/18722 0.450207751739527 0.60220818533796 HSPA5 1 GO:1903083 protein localization to condensed chromosome 1/580 19/18722 0.450207751739527 0.60220818533796 CDK1 1 GO:1903975 regulation of glial cell migration 1/580 19/18722 0.450207751739527 0.60220818533796 LRP1 1 GO:2000251 positive regulation of actin cytoskeleton reorganization 1/580 19/18722 0.450207751739527 0.60220818533796 CDC42 1 GO:2000269 regulation of fibroblast apoptotic process 1/580 19/18722 0.450207751739527 0.60220818533796 BTG1 1 GO:2000369 regulation of clathrin-dependent endocytosis 1/580 19/18722 0.450207751739527 0.60220818533796 AAK1 1 GO:2000738 positive regulation of stem cell differentiation 1/580 19/18722 0.450207751739527 0.60220818533796 TACSTD2 1 GO:0002762 negative regulation of myeloid leukocyte differentiation 2/580 49/18722 0.451105852014073 0.60220818533796 FBN1/CDK6 2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 2/580 49/18722 0.451105852014073 0.60220818533796 BMP7/CSNK2B 2 GO:0021695 cerebellar cortex development 2/580 49/18722 0.451105852014073 0.60220818533796 HSPA5/NAGLU 2 GO:0030225 macrophage differentiation 2/580 49/18722 0.451105852014073 0.60220818533796 APP/CDC42 2 GO:0038084 vascular endothelial growth factor signaling pathway 2/580 49/18722 0.451105852014073 0.60220818533796 NRP2/SEMA6A 2 GO:0042461 photoreceptor cell development 2/580 49/18722 0.451105852014073 0.60220818533796 NAGLU/TUG1 2 GO:0043457 regulation of cellular respiration 2/580 49/18722 0.451105852014073 0.60220818533796 IL10RB/RHOA 2 GO:0048168 regulation of neuronal synaptic plasticity 2/580 49/18722 0.451105852014073 0.60220818533796 APP/RAB11A 2 GO:0050832 defense response to fungus 2/580 49/18722 0.451105852014073 0.60220818533796 GAPDH/S100A9 2 GO:0051445 regulation of meiotic cell cycle 2/580 49/18722 0.451105852014073 0.60220818533796 DUSP1/ASPM 2 GO:0060986 endocrine hormone secretion 2/580 49/18722 0.451105852014073 0.60220818533796 GJA1/TBX3 2 GO:0072666 establishment of protein localization to vacuole 2/580 49/18722 0.451105852014073 0.60220818533796 GCC2/HSPA8 2 GO:1990928 response to amino acid starvation 2/580 49/18722 0.451105852014073 0.60220818533796 SLC38A2/EIF2AK4 2 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 4/580 111/18722 0.451856524089974 0.602691337408222 EGFR/ERBB3/IGF1R/MYDGF 4 GO:0071867 response to monoamine 4/580 111/18722 0.451856524089974 0.602691337408222 APP/NCSTN/SLC9A1/ID1 4 GO:0071869 response to catecholamine 4/580 111/18722 0.451856524089974 0.602691337408222 APP/NCSTN/SLC9A1/ID1 4 GO:0021766 hippocampus development 3/580 80/18722 0.452811810272278 0.603446340852827 GLI3/KIF5B/CDK6 3 GO:0051303 establishment of chromosome localization 3/580 80/18722 0.452811810272278 0.603446340852827 DYNC1H1/CENPF/RAB11A 3 GO:1901264 carbohydrate derivative transport 3/580 80/18722 0.452811810272278 0.603446340852827 PSAP/GJA1/SLC19A1 3 GO:0031023 microtubule organizing center organization 5/580 143/18722 0.456162245596428 0.607737211191346 GCC2/NPM1/E2F4/CDK1/RANBP1 5 GO:0035601 protein deacylation 4/580 112/18722 0.458705664507595 0.610775850450851 KDM5A/NOTUM/NIPBL/MORF4L2 4 GO:0043406 positive regulation of MAP kinase activity 4/580 112/18722 0.458705664507595 0.610775850450851 EGFR/IQGAP1/ERP29/MAGED1 4 GO:0051056 regulation of small GTPase mediated signal transduction 10/580 302/18722 0.460445776953618 0.611875506104209 ITGAV/ADGRG1/ITGB1/KANK1/MET/FAM13A/ARHGAP21/RASA1/STMN1/DYNLT1 10 GO:0046209 nitric oxide metabolic process 3/580 81/18722 0.460901067734111 0.611875506104209 POR/CAV1/DYNLL1 3 GO:2001021 negative regulation of response to DNA damage stimulus 3/580 81/18722 0.460901067734111 0.611875506104209 TPT1/PPP1R10/MIF 3 GO:0002639 positive regulation of immunoglobulin production 2/580 50/18722 0.461504896885308 0.611875506104209 TFRC/XBP1 2 GO:0006220 pyrimidine nucleotide metabolic process 2/580 50/18722 0.461504896885308 0.611875506104209 DUT/TYMS 2 GO:0010665 regulation of cardiac muscle cell apoptotic process 2/580 50/18722 0.461504896885308 0.611875506104209 PPP1R10/HMGCR 2 GO:0018023 peptidyl-lysine trimethylation 2/580 50/18722 0.461504896885308 0.611875506104209 ATRX/BRD4 2 GO:0019083 viral transcription 2/580 50/18722 0.461504896885308 0.611875506104209 JUN/RSF1 2 GO:0030490 maturation of SSU-rRNA 2/580 50/18722 0.461504896885308 0.611875506104209 RPS21/RPS16 2 GO:0043628 ncRNA 3'-end processing 2/580 50/18722 0.461504896885308 0.611875506104209 RPS21/FBL 2 GO:0045814 negative regulation of gene expression, epigenetic 2/580 50/18722 0.461504896885308 0.611875506104209 TPR/MPHOSPH8 2 GO:0070231 T cell apoptotic process 2/580 50/18722 0.461504896885308 0.611875506104209 RPS6/GLI3 2 GO:0071709 membrane assembly 2/580 50/18722 0.461504896885308 0.611875506104209 SPTBN1/CAV1 2 GO:0099054 presynapse assembly 2/580 50/18722 0.461504896885308 0.611875506104209 APP/EIF4G1 2 GO:1904036 negative regulation of epithelial cell apoptotic process 2/580 50/18722 0.461504896885308 0.611875506104209 TCF7L2/SRSF6 2 GO:0014065 phosphatidylinositol 3-kinase signaling 5/580 144/18722 0.462190271011144 0.612609561263275 EGFR/ZFP36L1/ERBB3/IGF1R/MYDGF 5 GO:0002834 regulation of response to tumor cell 1/580 20/18722 0.467257396394987 0.613902302438725 HMGB1 1 GO:0002837 regulation of immune response to tumor cell 1/580 20/18722 0.467257396394987 0.613902302438725 HMGB1 1 GO:0006346 DNA methylation-dependent heterochromatin assembly 1/580 20/18722 0.467257396394987 0.613902302438725 MPHOSPH8 1 GO:0006837 serotonin transport 1/580 20/18722 0.467257396394987 0.613902302438725 SLC6A4 1 GO:0006851 mitochondrial calcium ion transmembrane transport 1/580 20/18722 0.467257396394987 0.613902302438725 VDAC1 1 GO:0006883 cellular sodium ion homeostasis 1/580 20/18722 0.467257396394987 0.613902302438725 SLC9A1 1 GO:0007620 copulation 1/580 20/18722 0.467257396394987 0.613902302438725 SLC6A4 1 GO:0014047 glutamate secretion 1/580 20/18722 0.467257396394987 0.613902302438725 GJA1 1 GO:0016553 base conversion or substitution editing 1/580 20/18722 0.467257396394987 0.613902302438725 RBM47 1 GO:0021516 dorsal spinal cord development 1/580 20/18722 0.467257396394987 0.613902302438725 LMO4 1 GO:0031645 negative regulation of nervous system process 1/580 20/18722 0.467257396394987 0.613902302438725 CTSC 1 GO:0032495 response to muramyl dipeptide 1/580 20/18722 0.467257396394987 0.613902302438725 NFKBIA 1 GO:0032986 protein-DNA complex disassembly 1/580 20/18722 0.467257396394987 0.613902302438725 RPL23 1 GO:0039535 regulation of RIG-I signaling pathway 1/580 20/18722 0.467257396394987 0.613902302438725 PUM1 1 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate 1/580 20/18722 0.467257396394987 0.613902302438725 MPHOSPH8 1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process 1/580 20/18722 0.467257396394987 0.613902302438725 ITM2B 1 GO:0043011 myeloid dendritic cell differentiation 1/580 20/18722 0.467257396394987 0.613902302438725 DHRS2 1 GO:0043651 linoleic acid metabolic process 1/580 20/18722 0.467257396394987 0.613902302438725 CYP2J2 1 GO:0045063 T-helper 1 cell differentiation 1/580 20/18722 0.467257396394987 0.613902302438725 HMGB1 1 GO:0046629 gamma-delta T cell activation 1/580 20/18722 0.467257396394987 0.613902302438725 SOX4 1 GO:0046931 pore complex assembly 1/580 20/18722 0.467257396394987 0.613902302438725 RTN4 1 GO:0048670 regulation of collateral sprouting 1/580 20/18722 0.467257396394987 0.613902302438725 LRP1 1 GO:0061318 renal filtration cell differentiation 1/580 20/18722 0.467257396394987 0.613902302438725 IQGAP1 1 GO:0071397 cellular response to cholesterol 1/580 20/18722 0.467257396394987 0.613902302438725 DAG1 1 GO:0071625 vocalization behavior 1/580 20/18722 0.467257396394987 0.613902302438725 GLI3 1 GO:0072112 glomerular visceral epithelial cell differentiation 1/580 20/18722 0.467257396394987 0.613902302438725 IQGAP1 1 GO:0090201 negative regulation of release of cytochrome c from mitochondria 1/580 20/18722 0.467257396394987 0.613902302438725 GPX1 1 GO:0097150 neuronal stem cell population maintenance 1/580 20/18722 0.467257396394987 0.613902302438725 ASPM 1 GO:1901386 negative regulation of voltage-gated calcium channel activity 1/580 20/18722 0.467257396394987 0.613902302438725 CALM1 1 GO:1903817 negative regulation of voltage-gated potassium channel activity 1/580 20/18722 0.467257396394987 0.613902302438725 CAV1 1 GO:1990182 exosomal secretion 1/580 20/18722 0.467257396394987 0.613902302438725 RAB11A 1 GO:0016575 histone deacetylation 3/580 82/18722 0.46893838855071 0.615241874513216 KDM5A/NIPBL/MORF4L2 3 GO:0043242 negative regulation of protein-containing complex disassembly 3/580 82/18722 0.46893838855071 0.615241874513216 SPTAN1/SPTBN1/TRIOBP 3 GO:0046364 monosaccharide biosynthetic process 3/580 82/18722 0.46893838855071 0.615241874513216 DDB1/TPI1/PGP 3 GO:0050000 chromosome localization 3/580 82/18722 0.46893838855071 0.615241874513216 DYNC1H1/CENPF/RAB11A 3 GO:2001057 reactive nitrogen species metabolic process 3/580 82/18722 0.46893838855071 0.615241874513216 POR/CAV1/DYNLL1 3 GO:0006333 chromatin assembly or disassembly 6/580 177/18722 0.469908925440677 0.616167581681587 ATRX/NPM1/RSF1/HMGB1/HMGB2/DNAJC9 6 GO:0051648 vesicle localization 6/580 177/18722 0.469908925440677 0.616167581681587 DYNC1H1/TRIP11/TMED9/KIF5B/PRKCZ/RAB11A 6 GO:0071222 cellular response to lipopolysaccharide 7/580 209/18722 0.471068255043309 0.617513656766186 PABPN1/XBP1/CD55/NFKBIA/RHOA/HMGB1/HMGB2 7 GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 2/580 51/18722 0.471787690607881 0.617760289700804 PRKCZ/HMGB1 2 GO:0048013 ephrin receptor signaling pathway 2/580 51/18722 0.471787690607881 0.617760289700804 EPHB4/RASA1 2 GO:0065002 intracellular protein transmembrane transport 2/580 51/18722 0.471787690607881 0.617760289700804 HSPA5/SEC62 2 GO:0071622 regulation of granulocyte chemotaxis 2/580 51/18722 0.471787690607881 0.617760289700804 DPP4/JAM3 2 GO:0019751 polyol metabolic process 4/580 114/18722 0.472314461994383 0.61792814704244 PLPP3/ISYNA1/TPI1/PGP 4 GO:1901800 positive regulation of proteasomal protein catabolic process 4/580 114/18722 0.472314461994383 0.61792814704244 HSPA1A/TMEM259/HECTD1/CAV1 4 GO:1903008 organelle disassembly 4/580 114/18722 0.472314461994383 0.61792814704244 UFL1/KIF5B/VDAC1/CDK1 4 GO:0043367 CD4-positive, alpha-beta T cell differentiation 3/580 83/18722 0.476921627770558 0.622250288729898 CTSL/PRKCZ/HMGB1 3 GO:0034968 histone lysine methylation 4/580 115/18722 0.479071090886012 0.622250288729898 ATRX/KMT2C/BRD4/NSD1 4 GO:0042471 ear morphogenesis 4/580 115/18722 0.479071090886012 0.622250288729898 NAGLU/NIPBL/TRIOBP/TFAP2A 4 GO:0060041 retina development in camera-type eye 5/580 147/18722 0.480151838747459 0.622250288729898 ATP2B1/NAGLU/SERPINF1/LRP5/TFAP2A 5 GO:1903531 negative regulation of secretion by cell 5/580 147/18722 0.480151838747459 0.622250288729898 ERP29/GJA1/HMGCR/FRMD4A/GNAI2 5 GO:0042180 cellular ketone metabolic process 7/580 211/18722 0.481027900317559 0.622250288729898 EGR1/ADM/HMGCR/TPI1/CAV1/HSD17B1/ACADVL 7 GO:0002697 regulation of immune effector process 11/580 339/18722 0.481033325014699 0.622250288729898 GRN/CD46/CADM1/PRKDC/TFRC/CD81/XBP1/CD55/PRKCZ/SERPINB9/HMGB1 11 GO:0006790 sulfur compound metabolic process 11/580 339/18722 0.481033325014699 0.622250288729898 SLC26A2/CHPF/TPST2/CHST12/ACSS1/GNS/PTGES2/GSTO1/ARL6IP5/GPX1/CLIC3 11 GO:0002218 activation of innate immune response 2/580 52/18722 0.481951448229807 0.622250288729898 PRKDC/HMGB1 2 GO:0034204 lipid translocation 2/580 52/18722 0.481951448229807 0.622250288729898 KCNN4/ATP10D 2 GO:0045010 actin nucleation 2/580 52/18722 0.481951448229807 0.622250288729898 IQGAP2/WASF2 2 GO:0051496 positive regulation of stress fiber assembly 2/580 52/18722 0.481951448229807 0.622250288729898 RHOA/CDC42 2 GO:1903426 regulation of reactive oxygen species biosynthetic process 2/580 52/18722 0.481951448229807 0.622250288729898 RHOA/CYBA 2 GO:0000002 mitochondrial genome maintenance 1/580 21/18722 0.483779196742058 0.622250288729898 SLC25A36 1 GO:0003177 pulmonary valve development 1/580 21/18722 0.483779196742058 0.622250288729898 GJA5 1 GO:0006067 ethanol metabolic process 1/580 21/18722 0.483779196742058 0.622250288729898 ACSS1 1 GO:0006244 pyrimidine nucleotide catabolic process 1/580 21/18722 0.483779196742058 0.622250288729898 DUT 1 GO:0006353 DNA-templated transcription, termination 1/580 21/18722 0.483779196742058 0.622250288729898 POLR2A 1 GO:0006450 regulation of translational fidelity 1/580 21/18722 0.483779196742058 0.622250288729898 IARS2 1 GO:0006925 inflammatory cell apoptotic process 1/580 21/18722 0.483779196742058 0.622250288729898 CTSL 1 GO:0007063 regulation of sister chromatid cohesion 1/580 21/18722 0.483779196742058 0.622250288729898 ATRX 1 GO:0007289 spermatid nucleus differentiation 1/580 21/18722 0.483779196742058 0.622250288729898 HMGB2 1 GO:0007617 mating behavior 1/580 21/18722 0.483779196742058 0.622250288729898 APP 1 GO:0019370 leukotriene biosynthetic process 1/580 21/18722 0.483779196742058 0.622250288729898 MGST3 1 GO:0019985 translesion synthesis 1/580 21/18722 0.483779196742058 0.622250288729898 PCNA 1 GO:0022010 central nervous system myelination 1/580 21/18722 0.483779196742058 0.622250288729898 NCSTN 1 GO:0031145 anaphase-promoting complex-dependent catabolic process 1/580 21/18722 0.483779196742058 0.622250288729898 ANAPC11 1 GO:0032291 axon ensheathment in central nervous system 1/580 21/18722 0.483779196742058 0.622250288729898 NCSTN 1 GO:0033630 positive regulation of cell adhesion mediated by integrin 1/580 21/18722 0.483779196742058 0.622250288729898 FERMT1 1 GO:0033962 P-body assembly 1/580 21/18722 0.483779196742058 0.622250288729898 DYNC1H1 1 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation 1/580 21/18722 0.483779196742058 0.622250288729898 WASF2 1 GO:0035020 regulation of Rac protein signal transduction 1/580 21/18722 0.483779196742058 0.622250288729898 DYNLT1 1 GO:0035455 response to interferon-alpha 1/580 21/18722 0.483779196742058 0.622250288729898 TPR 1 GO:0035813 regulation of renal sodium excretion 1/580 21/18722 0.483779196742058 0.622250288729898 GNAI2 1 GO:0043373 CD4-positive, alpha-beta T cell lineage commitment 1/580 21/18722 0.483779196742058 0.622250288729898 CTSL 1 GO:0044342 type B pancreatic cell proliferation 1/580 21/18722 0.483779196742058 0.622250288729898 SERPINB1 1 GO:0045717 negative regulation of fatty acid biosynthetic process 1/580 21/18722 0.483779196742058 0.622250288729898 ACADVL 1 GO:0046519 sphingoid metabolic process 1/580 21/18722 0.483779196742058 0.622250288729898 PLPP3 1 GO:0046599 regulation of centriole replication 1/580 21/18722 0.483779196742058 0.622250288729898 NPM1 1 GO:0048199 vesicle targeting, to, from or within Golgi 1/580 21/18722 0.483779196742058 0.622250288729898 TMED9 1 GO:0048714 positive regulation of oligodendrocyte differentiation 1/580 21/18722 0.483779196742058 0.622250288729898 DAG1 1 GO:0050802 circadian sleep/wake cycle, sleep 1/580 21/18722 0.483779196742058 0.622250288729898 ADRB1 1 GO:0060117 auditory receptor cell development 1/580 21/18722 0.483779196742058 0.622250288729898 TRIOBP 1 GO:0060972 left/right pattern formation 1/580 21/18722 0.483779196742058 0.622250288729898 CITED2 1 GO:0070584 mitochondrion morphogenesis 1/580 21/18722 0.483779196742058 0.622250288729898 PLEC 1 GO:0071605 monocyte chemotactic protein-1 production 1/580 21/18722 0.483779196742058 0.622250288729898 HMGB1 1 GO:0071637 regulation of monocyte chemotactic protein-1 production 1/580 21/18722 0.483779196742058 0.622250288729898 HMGB1 1 GO:0072170 metanephric tubule development 1/580 21/18722 0.483779196742058 0.622250288729898 LGR4 1 GO:0072243 metanephric nephron epithelium development 1/580 21/18722 0.483779196742058 0.622250288729898 LGR4 1 GO:0072311 glomerular epithelial cell differentiation 1/580 21/18722 0.483779196742058 0.622250288729898 IQGAP1 1 GO:0097062 dendritic spine maintenance 1/580 21/18722 0.483779196742058 0.622250288729898 IGF1R 1 GO:0097734 extracellular exosome biogenesis 1/580 21/18722 0.483779196742058 0.622250288729898 RAB11A 1 GO:0098719 sodium ion import across plasma membrane 1/580 21/18722 0.483779196742058 0.622250288729898 SLC9A1 1 GO:0099515 actin filament-based transport 1/580 21/18722 0.483779196742058 0.622250288729898 SYNE2 1 GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1/580 21/18722 0.483779196742058 0.622250288729898 HSPA1A 1 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1/580 21/18722 0.483779196742058 0.622250288729898 MIF 1 GO:1902259 regulation of delayed rectifier potassium channel activity 1/580 21/18722 0.483779196742058 0.622250288729898 VAMP2 1 GO:1903427 negative regulation of reactive oxygen species biosynthetic process 1/580 21/18722 0.483779196742058 0.622250288729898 RHOA 1 GO:2000291 regulation of myoblast proliferation 1/580 21/18722 0.483779196742058 0.622250288729898 MALAT1 1 GO:2000774 positive regulation of cellular senescence 1/580 21/18722 0.483779196742058 0.622250288729898 YPEL3 1 GO:2001014 regulation of skeletal muscle cell differentiation 1/580 21/18722 0.483779196742058 0.622250288729898 GPC1 1 GO:0002088 lens development in camera-type eye 3/580 84/18722 0.484848748021857 0.622764851435972 CRYBG3/FAT1/CITED2 3 GO:0010660 regulation of muscle cell apoptotic process 3/580 84/18722 0.484848748021857 0.622764851435972 PPP1R10/HMGCR/BMP7 3 GO:0032370 positive regulation of lipid transport 3/580 84/18722 0.484848748021857 0.622764851435972 LRP1/CAV1/NFKBIA 3 GO:1900542 regulation of purine nucleotide metabolic process 3/580 84/18722 0.484848748021857 0.622764851435972 APP/ENO1/TMSB4X 3 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 3/580 84/18722 0.484848748021857 0.622764851435972 SOX4/PRKDC/CTDSPL 3 GO:0006720 isoprenoid metabolic process 4/580 116/18722 0.485793939615979 0.623462365660574 LRP2/LRP1/EGFR/HMGCR 4 GO:0031123 RNA 3'-end processing 4/580 116/18722 0.485793939615979 0.623462365660574 RPS21/APP/ZFP36L1/FBL 4 GO:0098732 macromolecule deacylation 4/580 116/18722 0.485793939615979 0.623462365660574 KDM5A/NOTUM/NIPBL/MORF4L2 4 GO:0006479 protein methylation 6/580 181/18722 0.491480628846618 0.630412687469835 BTG1/ATRX/KMT2C/BRD4/NSD1/FBL 6 GO:0008213 protein alkylation 6/580 181/18722 0.491480628846618 0.630412687469835 BTG1/ATRX/KMT2C/BRD4/NSD1/FBL 6 GO:0032210 regulation of telomere maintenance via telomerase 2/580 53/18722 0.491993668159636 0.63057412620439 HNRNPA1/HNRNPC 2 GO:0099172 presynapse organization 2/580 53/18722 0.491993668159636 0.63057412620439 APP/EIF4G1 2 GO:0016525 negative regulation of angiogenesis 5/580 149/18722 0.492013223821916 0.63057412620439 COL4A2/SEMA6A/SERPINF1/ADAMTS1/ROCK1 5 GO:0010507 negative regulation of autophagy 3/580 85/18722 0.492717817235376 0.631129321939338 MET/CTSA/EIF4G1 3 GO:0097006 regulation of plasma lipoprotein particle levels 3/580 85/18722 0.492717817235376 0.631129321939338 LRPAP1/CNPY2/MYLIP 3 GO:0002029 desensitization of G protein-coupled receptor signaling pathway 1/580 22/18722 0.499789467096028 0.634075507764219 ADM 1 GO:0002053 positive regulation of mesenchymal cell proliferation 1/580 22/18722 0.499789467096028 0.634075507764219 LRP5 1 GO:0002089 lens morphogenesis in camera-type eye 1/580 22/18722 0.499789467096028 0.634075507764219 CITED2 1 GO:0006662 glycerol ether metabolic process 1/580 22/18722 0.499789467096028 0.634075507764219 TXN 1 GO:0007413 axonal fasciculation 1/580 22/18722 0.499789467096028 0.634075507764219 RTN4 1 GO:0008211 glucocorticoid metabolic process 1/580 22/18722 0.499789467096028 0.634075507764219 YWHAH 1 GO:0014821 phasic smooth muscle contraction 1/580 22/18722 0.499789467096028 0.634075507764219 TBX3 1 GO:0021854 hypothalamus development 1/580 22/18722 0.499789467096028 0.634075507764219 NRP2 1 GO:0021904 dorsal/ventral neural tube patterning 1/580 22/18722 0.499789467096028 0.634075507764219 GLI3 1 GO:0022401 negative adaptation of signaling pathway 1/580 22/18722 0.499789467096028 0.634075507764219 ADM 1 GO:0022616 DNA strand elongation 1/580 22/18722 0.499789467096028 0.634075507764219 PCNA 1 GO:0032402 melanosome transport 1/580 22/18722 0.499789467096028 0.634075507764219 RAB11A 1 GO:0032700 negative regulation of interleukin-17 production 1/580 22/18722 0.499789467096028 0.634075507764219 DDIT3 1 GO:0032727 positive regulation of interferon-alpha production 1/580 22/18722 0.499789467096028 0.634075507764219 HMGB1 1 GO:0034629 cellular protein-containing complex localization 1/580 22/18722 0.499789467096028 0.634075507764219 AKAP9 1 GO:0034755 iron ion transmembrane transport 1/580 22/18722 0.499789467096028 0.634075507764219 SLC40A1 1 GO:0035357 peroxisome proliferator activated receptor signaling pathway 1/580 22/18722 0.499789467096028 0.634075507764219 CITED2 1 GO:0035561 regulation of chromatin binding 1/580 22/18722 0.499789467096028 0.634075507764219 GMNN 1 GO:0042749 regulation of circadian sleep/wake cycle 1/580 22/18722 0.499789467096028 0.634075507764219 ADRB1 1 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation 1/580 22/18722 0.499789467096028 0.634075507764219 HMGB1 1 GO:0044346 fibroblast apoptotic process 1/580 22/18722 0.499789467096028 0.634075507764219 BTG1 1 GO:0045061 thymic T cell selection 1/580 22/18722 0.499789467096028 0.634075507764219 GLI3 1 GO:0045540 regulation of cholesterol biosynthetic process 1/580 22/18722 0.499789467096028 0.634075507764219 POR 1 GO:0045624 positive regulation of T-helper cell differentiation 1/580 22/18722 0.499789467096028 0.634075507764219 PRKCZ 1 GO:0045663 positive regulation of myoblast differentiation 1/580 22/18722 0.499789467096028 0.634075507764219 BTG1 1 GO:0050860 negative regulation of T cell receptor signaling pathway 1/580 22/18722 0.499789467096028 0.634075507764219 PHPT1 1 GO:0055093 response to hyperoxia 1/580 22/18722 0.499789467096028 0.634075507764219 CAV1 1 GO:0060563 neuroepithelial cell differentiation 1/580 22/18722 0.499789467096028 0.634075507764219 SOX4 1 GO:0061042 vascular wound healing 1/580 22/18722 0.499789467096028 0.634075507764219 XBP1 1 GO:0071467 cellular response to pH 1/580 22/18722 0.499789467096028 0.634075507764219 SLC9A1 1 GO:0072574 hepatocyte proliferation 1/580 22/18722 0.499789467096028 0.634075507764219 XBP1 1 GO:0072575 epithelial cell proliferation involved in liver morphogenesis 1/580 22/18722 0.499789467096028 0.634075507764219 XBP1 1 GO:0106030 neuron projection fasciculation 1/580 22/18722 0.499789467096028 0.634075507764219 RTN4 1 GO:0106118 regulation of sterol biosynthetic process 1/580 22/18722 0.499789467096028 0.634075507764219 POR 1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus 1/580 22/18722 0.499789467096028 0.634075507764219 XBP1 1 GO:0006140 regulation of nucleotide metabolic process 3/580 86/18722 0.500527006333675 0.634838043757274 APP/ENO1/TMSB4X 3 GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2/580 54/18722 0.501912117336777 0.635728011365291 CD46/CD55 2 GO:0006968 cellular defense response 2/580 54/18722 0.501912117336777 0.635728011365291 LGALS3BP/ITGB1 2 GO:0010659 cardiac muscle cell apoptotic process 2/580 54/18722 0.501912117336777 0.635728011365291 PPP1R10/HMGCR 2 GO:0030520 intracellular estrogen receptor signaling pathway 2/580 54/18722 0.501912117336777 0.635728011365291 UFL1/ISL1 2 GO:0072698 protein localization to microtubule cytoskeleton 2/580 54/18722 0.501912117336777 0.635728011365291 GOLGB1/DIAPH1 2 GO:0006325 chromatin organization 13/580 409/18722 0.502264256486552 0.636000832267616 BPTF/ATRX/KDM5A/NPM1/BRD4/RSF1/HMGN3/TPR/MPHOSPH8/HNRNPC/HMGB1/HMGB2/DNAJC9 13 GO:0006261 DNA-dependent DNA replication 5/580 151/18722 0.503774570028848 0.637566129307257 BOD1L1/PURA/ATRX/PCNA/GMNN 5 GO:2000181 negative regulation of blood vessel morphogenesis 5/580 151/18722 0.503774570028848 0.637566129307257 COL4A2/SEMA6A/SERPINF1/ADAMTS1/ROCK1 5 GO:0016101 diterpenoid metabolic process 3/580 87/18722 0.508274586893096 0.642911368952894 LRP2/LRP1/EGFR 3 GO:1901879 regulation of protein depolymerization 3/580 87/18722 0.508274586893096 0.642911368952894 SPTAN1/SPTBN1/TRIOBP 3 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 8/580 249/18722 0.508733573357993 0.643316979251774 GAPDH/UFL1/WLS/GJA1/TFRC/BRD4/TMED4/RHOA 8 GO:0050871 positive regulation of B cell activation 5/580 152/18722 0.509615287604406 0.643904431953692 SLC39A10/TFRC/CD81/MIF/XBP1 5 GO:1901343 negative regulation of vasculature development 5/580 152/18722 0.509615287604406 0.643904431953692 COL4A2/SEMA6A/SERPINF1/ADAMTS1/ROCK1 5 GO:0008333 endosome to lysosome transport 2/580 55/18722 0.511704817046079 0.643904431953692 RHOB/HOOK2 2 GO:0045620 negative regulation of lymphocyte differentiation 2/580 55/18722 0.511704817046079 0.643904431953692 GLI3/HMGB1 2 GO:0048016 inositol phosphate-mediated signaling 2/580 55/18722 0.511704817046079 0.643904431953692 NFAT5/SLC9A1 2 GO:0051898 negative regulation of protein kinase B signaling 2/580 55/18722 0.511704817046079 0.643904431953692 DAG1/DDIT3 2 GO:1902991 regulation of amyloid precursor protein catabolic process 2/580 55/18722 0.511704817046079 0.643904431953692 ROCK1/RTN4 2 GO:1905517 macrophage migration 2/580 55/18722 0.511704817046079 0.643904431953692 CD81/MIF 2 GO:0002082 regulation of oxidative phosphorylation 1/580 23/18722 0.515304018383959 0.643904431953692 RHOA 1 GO:0003323 type B pancreatic cell development 1/580 23/18722 0.515304018383959 0.643904431953692 CDK6 1 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 1/580 23/18722 0.515304018383959 0.643904431953692 LRP1 1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules 1/580 23/18722 0.515304018383959 0.643904431953692 CLDN4 1 GO:0021544 subpallium development 1/580 23/18722 0.515304018383959 0.643904431953692 GLI3 1 GO:0021884 forebrain neuron development 1/580 23/18722 0.515304018383959 0.643904431953692 NRP2 1 GO:0023058 adaptation of signaling pathway 1/580 23/18722 0.515304018383959 0.643904431953692 ADM 1 GO:0031338 regulation of vesicle fusion 1/580 23/18722 0.515304018383959 0.643904431953692 KIF5B 1 GO:0032401 establishment of melanosome localization 1/580 23/18722 0.515304018383959 0.643904431953692 RAB11A 1 GO:0034105 positive regulation of tissue remodeling 1/580 23/18722 0.515304018383959 0.643904431953692 ROCK1 1 GO:0034695 response to prostaglandin E 1/580 23/18722 0.515304018383959 0.643904431953692 TGFBR3 1 GO:0035162 embryonic hemopoiesis 1/580 23/18722 0.515304018383959 0.643904431953692 PBX1 1 GO:0035640 exploration behavior 1/580 23/18722 0.515304018383959 0.643904431953692 DPP4 1 GO:0035812 renal sodium excretion 1/580 23/18722 0.515304018383959 0.643904431953692 GNAI2 1 GO:0035988 chondrocyte proliferation 1/580 23/18722 0.515304018383959 0.643904431953692 GOLGB1 1 GO:0036303 lymph vessel morphogenesis 1/580 23/18722 0.515304018383959 0.643904431953692 SVEP1 1 GO:0040019 positive regulation of embryonic development 1/580 23/18722 0.515304018383959 0.643904431953692 CFL1 1 GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment 1/580 23/18722 0.515304018383959 0.643904431953692 CTSL 1 GO:0043931 ossification involved in bone maturation 1/580 23/18722 0.515304018383959 0.643904431953692 RHOA 1 GO:0045943 positive regulation of transcription by RNA polymerase I 1/580 23/18722 0.515304018383959 0.643904431953692 NCL 1 GO:0050765 negative regulation of phagocytosis 1/580 23/18722 0.515304018383959 0.643904431953692 HMGB1 1 GO:0051457 maintenance of protein location in nucleus 1/580 23/18722 0.515304018383959 0.643904431953692 TXN 1 GO:0051590 positive regulation of neurotransmitter transport 1/580 23/18722 0.515304018383959 0.643904431953692 ITGB1 1 GO:0051904 pigment granule transport 1/580 23/18722 0.515304018383959 0.643904431953692 RAB11A 1 GO:0060353 regulation of cell adhesion molecule production 1/580 23/18722 0.515304018383959 0.643904431953692 CAV1 1 GO:0060384 innervation 1/580 23/18722 0.515304018383959 0.643904431953692 ISL1 1 GO:0060547 negative regulation of necrotic cell death 1/580 23/18722 0.515304018383959 0.643904431953692 CAV1 1 GO:0071218 cellular response to misfolded protein 1/580 23/18722 0.515304018383959 0.643904431953692 DNAJB14 1 GO:0071305 cellular response to vitamin D 1/580 23/18722 0.515304018383959 0.643904431953692 ATP2B1 1 GO:0071514 genetic imprinting 1/580 23/18722 0.515304018383959 0.643904431953692 IGF2 1 GO:0072576 liver morphogenesis 1/580 23/18722 0.515304018383959 0.643904431953692 XBP1 1 GO:0090335 regulation of brown fat cell differentiation 1/580 23/18722 0.515304018383959 0.643904431953692 BMP7 1 GO:0140112 extracellular vesicle biogenesis 1/580 23/18722 0.515304018383959 0.643904431953692 RAB11A 1 GO:1902410 mitotic cytokinetic process 1/580 23/18722 0.515304018383959 0.643904431953692 RHOA 1 GO:1903306 negative regulation of regulated secretory pathway 1/580 23/18722 0.515304018383959 0.643904431953692 GNAI2 1 GO:2000737 negative regulation of stem cell differentiation 1/580 23/18722 0.515304018383959 0.643904431953692 N4BP2L2 1 GO:0007338 single fertilization 5/580 153/18722 0.515428123019479 0.643904431953692 CD46/SPESP1/ALDOA/FOLR1/CDK1 5 GO:0120032 regulation of plasma membrane bounded cell projection assembly 6/580 186/18722 0.518025947609466 0.646976015663702 KANK1/TACSTD2/CAV1/WASF2/PFN1/CDC42 6 GO:0043244 regulation of protein-containing complex disassembly 4/580 121/18722 0.518854686502076 0.64766321710176 SPTAN1/SPTBN1/IGF1R/TRIOBP 4 GO:1904019 epithelial cell apoptotic process 4/580 121/18722 0.518854686502076 0.64766321710176 ZFP36L1/TCF7L2/KRT8/SRSF6 4 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 2/580 56/18722 0.521370029351103 0.649756700565911 ZFP36L1/TNRC6A 2 GO:0006687 glycosphingolipid metabolic process 2/580 56/18722 0.521370029351103 0.649756700565911 HEXA/NEU1 2 GO:0032608 interferon-beta production 2/580 56/18722 0.521370029351103 0.649756700565911 HMGB1/HMGB2 2 GO:0032648 regulation of interferon-beta production 2/580 56/18722 0.521370029351103 0.649756700565911 HMGB1/HMGB2 2 GO:0043470 regulation of carbohydrate catabolic process 2/580 56/18722 0.521370029351103 0.649756700565911 APP/HMGB1 2 GO:0055078 sodium ion homeostasis 2/580 56/18722 0.521370029351103 0.649756700565911 SLC9A1/GNAI2 2 GO:0010657 muscle cell apoptotic process 3/580 89/18722 0.52357849779885 0.652334206606604 PPP1R10/HMGCR/BMP7 3 GO:0001906 cell killing 6/580 188/18722 0.52849434909426 0.654729459188499 GAPDH/CADM1/CTSC/KIF5B/CD55/SERPINB9 6 GO:0060491 regulation of cell projection assembly 6/580 188/18722 0.52849434909426 0.654729459188499 KANK1/TACSTD2/CAV1/WASF2/PFN1/CDC42 6 GO:0071219 cellular response to molecule of bacterial origin 7/580 221/18722 0.529951314877672 0.654729459188499 PABPN1/XBP1/CD55/NFKBIA/RHOA/HMGB1/HMGB2 7 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/580 24/18722 0.530338173650942 0.654729459188499 RPS21 1 GO:0001702 gastrulation with mouth forming second 1/580 24/18722 0.530338173650942 0.654729459188499 LRP5 1 GO:0001783 B cell apoptotic process 1/580 24/18722 0.530338173650942 0.654729459188499 SLC39A10 1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity 1/580 24/18722 0.530338173650942 0.654729459188499 SERPINB9 1 GO:0002021 response to dietary excess 1/580 24/18722 0.530338173650942 0.654729459188499 ADRB1 1 GO:0003181 atrioventricular valve morphogenesis 1/580 24/18722 0.530338173650942 0.654729459188499 SOX4 1 GO:0010155 regulation of proton transport 1/580 24/18722 0.530338173650942 0.654729459188499 TMSB4X 1 GO:0010226 response to lithium ion 1/580 24/18722 0.530338173650942 0.654729459188499 CDH1 1 GO:0010288 response to lead ion 1/580 24/18722 0.530338173650942 0.654729459188499 APP 1 GO:0016048 detection of temperature stimulus 1/580 24/18722 0.530338173650942 0.654729459188499 NR2F6 1 GO:0022410 circadian sleep/wake cycle process 1/580 24/18722 0.530338173650942 0.654729459188499 ADRB1 1 GO:0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 1/580 24/18722 0.530338173650942 0.654729459188499 PUM1 1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 1/580 24/18722 0.530338173650942 0.654729459188499 GPC1 1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 1/580 24/18722 0.530338173650942 0.654729459188499 PHIP 1 GO:0044062 regulation of excretion 1/580 24/18722 0.530338173650942 0.654729459188499 GNAI2 1 GO:0044321 response to leptin 1/580 24/18722 0.530338173650942 0.654729459188499 LRP2 1 GO:0051000 positive regulation of nitric-oxide synthase activity 1/580 24/18722 0.530338173650942 0.654729459188499 CALM1 1 GO:0051123 RNA polymerase II preinitiation complex assembly 1/580 24/18722 0.530338173650942 0.654729459188499 HMGB1 1 GO:0051570 regulation of histone H3-K9 methylation 1/580 24/18722 0.530338173650942 0.654729459188499 ATRX 1 GO:0051905 establishment of pigment granule localization 1/580 24/18722 0.530338173650942 0.654729459188499 RAB11A 1 GO:0051923 sulfation 1/580 24/18722 0.530338173650942 0.654729459188499 TPST2 1 GO:0060571 morphogenesis of an epithelial fold 1/580 24/18722 0.530338173650942 0.654729459188499 BMP7 1 GO:0070935 3'-UTR-mediated mRNA stabilization 1/580 24/18722 0.530338173650942 0.654729459188499 HNRNPC 1 GO:0071676 negative regulation of mononuclear cell migration 1/580 24/18722 0.530338173650942 0.654729459188499 DUSP1 1 GO:0072010 glomerular epithelium development 1/580 24/18722 0.530338173650942 0.654729459188499 IQGAP1 1 GO:0072530 purine-containing compound transmembrane transport 1/580 24/18722 0.530338173650942 0.654729459188499 SLC19A1 1 GO:0090343 positive regulation of cell aging 1/580 24/18722 0.530338173650942 0.654729459188499 YPEL3 1 GO:1903428 positive regulation of reactive oxygen species biosynthetic process 1/580 24/18722 0.530338173650942 0.654729459188499 CYBA 1 GO:2000310 regulation of NMDA receptor activity 1/580 24/18722 0.530338173650942 0.654729459188499 APP 1 GO:0016447 somatic recombination of immunoglobulin gene segments 2/580 57/18722 0.530906244121472 0.654729459188499 PRKDC/TFRC 2 GO:0030219 megakaryocyte differentiation 2/580 57/18722 0.530906244121472 0.654729459188499 WASF2/HMGB2 2 GO:0050879 multicellular organismal movement 2/580 57/18722 0.530906244121472 0.654729459188499 GAA/GSTO1 2 GO:0050881 musculoskeletal movement 2/580 57/18722 0.530906244121472 0.654729459188499 GAA/GSTO1 2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 3/580 90/18722 0.531131853261279 0.654729459188499 HSPA1A/HECTD1/CAV1 3 GO:0048477 oogenesis 3/580 90/18722 0.531131853261279 0.654729459188499 LGR5/RPS6/ASPM 3 GO:0061097 regulation of protein tyrosine kinase activity 3/580 90/18722 0.531131853261279 0.654729459188499 APP/ERBB3/CAV1 3 GO:0099175 regulation of postsynapse organization 3/580 90/18722 0.531131853261279 0.654729459188499 NRP2/CFL1/HSPA8 3 GO:0009165 nucleotide biosynthetic process 8/580 254/18722 0.531348427050948 0.654822876050333 SLC26A2/ALDOA/ENO1/ACSS1/TMSB4X/DUT/TYMS/RRM2 8 GO:0030168 platelet activation 4/580 123/18722 0.531797799375225 0.655029545787651 PPIA/IL6ST/ACTG1/MYL12A 4 GO:0071482 cellular response to light stimulus 4/580 123/18722 0.531797799375225 0.655029545787651 DDB1/NPM1/EIF2AK4/PCNA 4 GO:0009060 aerobic respiration 6/580 189/18722 0.533693678680106 0.657190706788767 COX6A1/NDUFB9/RHOA/UQCRH/COX8C/CDK1 6 GO:0006066 alcohol metabolic process 11/580 353/18722 0.535247790094167 0.658929981929055 APP/PLPP3/DHCR24/LRP5/ACSS1/ISYNA1/HMGCR/POR/TPI1/ACADVL/PGP 11 GO:0006338 chromatin remodeling 8/580 255/18722 0.535825937843478 0.659467170391643 BPTF/ATRX/KDM5A/NPM1/RSF1/HNRNPC/HMGB2/DNAJC9 8 GO:0001909 leukocyte mediated cytotoxicity 4/580 124/18722 0.538204631026284 0.661986050946092 CADM1/CTSC/KIF5B/SERPINB9 4 GO:0007368 determination of left/right symmetry 4/580 124/18722 0.538204631026284 0.661986050946092 FOLR1/TBX3/GALNT11/CITED2 4 GO:1902600 proton transmembrane transport 5/580 157/18722 0.538383091345118 0.661986050946092 COX6A1/ATP6AP1/SLC9A1/TMSB4X/UQCRH 5 GO:0002275 myeloid cell activation involved in immune response 3/580 91/18722 0.538617645641124 0.661986050946092 GRN/VAMP2/HMGB1 3 GO:0051952 regulation of amine transport 3/580 91/18722 0.538617645641124 0.661986050946092 ITGB1/SLC43A2/ARL6IP5 3 GO:0009566 fertilization 6/580 190/18722 0.53886888602062 0.661986050946092 CD46/SPESP1/ALDOA/FOLR1/NR2F2/CDK1 6 GO:0046390 ribose phosphate biosynthetic process 6/580 190/18722 0.53886888602062 0.661986050946092 SLC26A2/ALDOA/ENO1/ACSS1/TMSB4X/PYGL 6 GO:1901293 nucleoside phosphate biosynthetic process 8/580 256/18722 0.540287228250396 0.662058894500872 SLC26A2/ALDOA/ENO1/ACSS1/TMSB4X/DUT/TYMS/RRM2 8 GO:0007405 neuroblast proliferation 2/580 58/18722 0.540312166630603 0.662058894500872 GLI3/ASPM 2 GO:0010574 regulation of vascular endothelial growth factor production 2/580 58/18722 0.540312166630603 0.662058894500872 ISL1/IL6ST 2 GO:0044380 protein localization to cytoskeleton 2/580 58/18722 0.540312166630603 0.662058894500872 GOLGB1/DIAPH1 2 GO:0097035 regulation of membrane lipid distribution 2/580 58/18722 0.540312166630603 0.662058894500872 KCNN4/ATP10D 2 GO:0051053 negative regulation of DNA metabolic process 4/580 125/18722 0.544566963633766 0.662058894500872 DUSP1/GJA1/HNRNPA1/HNRNPC 4 GO:0006658 phosphatidylserine metabolic process 1/580 25/18722 0.544906783089516 0.662058894500872 SERINC1 1 GO:0010842 retina layer formation 1/580 25/18722 0.544906783089516 0.662058894500872 TFAP2A 1 GO:0010954 positive regulation of protein processing 1/580 25/18722 0.544906783089516 0.662058894500872 ENO1 1 GO:0021846 cell proliferation in forebrain 1/580 25/18722 0.544906783089516 0.662058894500872 GLI3 1 GO:0030318 melanocyte differentiation 1/580 25/18722 0.544906783089516 0.662058894500872 GLI3 1 GO:0031579 membrane raft organization 1/580 25/18722 0.544906783089516 0.662058894500872 CAV1 1 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 1/580 25/18722 0.544906783089516 0.662058894500872 CD55 1 GO:0032331 negative regulation of chondrocyte differentiation 1/580 25/18722 0.544906783089516 0.662058894500872 EFEMP1 1 GO:0032400 melanosome localization 1/580 25/18722 0.544906783089516 0.662058894500872 RAB11A 1 GO:0032753 positive regulation of interleukin-4 production 1/580 25/18722 0.544906783089516 0.662058894500872 PRKCZ 1 GO:0032925 regulation of activin receptor signaling pathway 1/580 25/18722 0.544906783089516 0.662058894500872 CSNK2B 1 GO:0033233 regulation of protein sumoylation 1/580 25/18722 0.544906783089516 0.662058894500872 EGR1 1 GO:0034389 lipid droplet organization 1/580 25/18722 0.544906783089516 0.662058894500872 PPIA 1 GO:0035902 response to immobilization stress 1/580 25/18722 0.544906783089516 0.662058894500872 FOS 1 GO:0036315 cellular response to sterol 1/580 25/18722 0.544906783089516 0.662058894500872 DAG1 1 GO:0045324 late endosome to vacuole transport 1/580 25/18722 0.544906783089516 0.662058894500872 LEPROT 1 GO:0050951 sensory perception of temperature stimulus 1/580 25/18722 0.544906783089516 0.662058894500872 NR2F6 1 GO:0051291 protein heterooligomerization 1/580 25/18722 0.544906783089516 0.662058894500872 RRM2 1 GO:0051788 response to misfolded protein 1/580 25/18722 0.544906783089516 0.662058894500872 DNAJB14 1 GO:0060074 synapse maturation 1/580 25/18722 0.544906783089516 0.662058894500872 PFN1 1 GO:0060740 prostate gland epithelium morphogenesis 1/580 25/18722 0.544906783089516 0.662058894500872 BMP7 1 GO:0062009 secondary palate development 1/580 25/18722 0.544906783089516 0.662058894500872 TGFBR3 1 GO:0062149 detection of stimulus involved in sensory perception of pain 1/580 25/18722 0.544906783089516 0.662058894500872 NR2F6 1 GO:0070199 establishment of protein localization to chromosome 1/580 25/18722 0.544906783089516 0.662058894500872 NIPBL 1 GO:0071459 protein localization to chromosome, centromeric region 1/580 25/18722 0.544906783089516 0.662058894500872 CDK1 1 GO:0072202 cell differentiation involved in metanephros development 1/580 25/18722 0.544906783089516 0.662058894500872 LGR4 1 GO:0072207 metanephric epithelium development 1/580 25/18722 0.544906783089516 0.662058894500872 LGR4 1 GO:0086013 membrane repolarization during cardiac muscle cell action potential 1/580 25/18722 0.544906783089516 0.662058894500872 YWHAE 1 GO:0090312 positive regulation of protein deacetylation 1/580 25/18722 0.544906783089516 0.662058894500872 NIPBL 1 GO:0090330 regulation of platelet aggregation 1/580 25/18722 0.544906783089516 0.662058894500872 IL6ST 1 GO:0099560 synaptic membrane adhesion 1/580 25/18722 0.544906783089516 0.662058894500872 PTPRF 1 GO:1902932 positive regulation of alcohol biosynthetic process 1/580 25/18722 0.544906783089516 0.662058894500872 POR 1 GO:1903055 positive regulation of extracellular matrix organization 1/580 25/18722 0.544906783089516 0.662058894500872 DAG1 1 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA 1/580 25/18722 0.544906783089516 0.662058894500872 EGFR 1 GO:1903901 negative regulation of viral life cycle 1/580 25/18722 0.544906783089516 0.662058894500872 PPIA 1 GO:1904753 negative regulation of vascular associated smooth muscle cell migration 1/580 25/18722 0.544906783089516 0.662058894500872 RHOA 1 GO:0031058 positive regulation of histone modification 3/580 92/18722 0.54603461415979 0.663082765132424 ISL1/BRD4/NIPBL 3 GO:0034502 protein localization to chromosome 3/580 92/18722 0.54603461415979 0.663082765132424 ATRX/NIPBL/CDK1 3 GO:0002820 negative regulation of adaptive immune response 2/580 59/18722 0.549586705701043 0.666699991709846 CD46/CD55 2 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 2/580 59/18722 0.549586705701043 0.666699991709846 CAV1/PRKCZ 2 GO:0051055 negative regulation of lipid biosynthetic process 2/580 59/18722 0.549586705701043 0.666699991709846 ORMDL1/ACADVL 2 GO:0071806 protein transmembrane transport 2/580 59/18722 0.549586705701043 0.666699991709846 HSPA5/SEC62 2 GO:0033108 mitochondrial respiratory chain complex assembly 3/580 93/18722 0.553381584402176 0.670778667983977 PET100/NDUFB9/COX20 3 GO:0097306 cellular response to alcohol 3/580 93/18722 0.553381584402176 0.670778667983977 ATP2B1/DAG1/CDH1 3 GO:1902807 negative regulation of cell cycle G1/S phase transition 3/580 93/18722 0.553381584402176 0.670778667983977 SOX4/PRKDC/CTDSPL 3 GO:0006289 nucleotide-excision repair 2/580 60/18722 0.558728962375456 0.671666683999115 DDB1/HMGB1 2 GO:0009620 response to fungus 2/580 60/18722 0.558728962375456 0.671666683999115 GAPDH/S100A9 2 GO:0031663 lipopolysaccharide-mediated signaling pathway 2/580 60/18722 0.558728962375456 0.671666683999115 CD55/NFKBIA 2 GO:0033866 nucleoside bisphosphate biosynthetic process 2/580 60/18722 0.558728962375456 0.671666683999115 SLC26A2/ACSS1 2 GO:0034030 ribonucleoside bisphosphate biosynthetic process 2/580 60/18722 0.558728962375456 0.671666683999115 SLC26A2/ACSS1 2 GO:0034033 purine nucleoside bisphosphate biosynthetic process 2/580 60/18722 0.558728962375456 0.671666683999115 SLC26A2/ACSS1 2 GO:0051965 positive regulation of synapse assembly 2/580 60/18722 0.558728962375456 0.671666683999115 TPBG/DLG5 2 GO:0001963 synaptic transmission, dopaminergic 1/580 26/18722 0.559024238606875 0.671666683999115 SLC6A4 1 GO:0002407 dendritic cell chemotaxis 1/580 26/18722 0.559024238606875 0.671666683999115 HMGB1 1 GO:0002418 immune response to tumor cell 1/580 26/18722 0.559024238606875 0.671666683999115 HMGB1 1 GO:0003416 endochondral bone growth 1/580 26/18722 0.559024238606875 0.671666683999115 POR 1 GO:0006517 protein deglycosylation 1/580 26/18722 0.559024238606875 0.671666683999115 MAN1A2 1 GO:0006706 steroid catabolic process 1/580 26/18722 0.559024238606875 0.671666683999115 YWHAH 1 GO:0021952 central nervous system projection neuron axonogenesis 1/580 26/18722 0.559024238606875 0.671666683999115 MYCBP2 1 GO:0031167 rRNA methylation 1/580 26/18722 0.559024238606875 0.671666683999115 FBL 1 GO:0033522 histone H2A ubiquitination 1/580 26/18722 0.559024238606875 0.671666683999115 DDB1 1 GO:0034114 regulation of heterotypic cell-cell adhesion 1/580 26/18722 0.559024238606875 0.671666683999115 BMP7 1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated 1/580 26/18722 0.559024238606875 0.671666683999115 ARMCX3 1 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity 1/580 26/18722 0.559024238606875 0.671666683999115 CADM1 1 GO:0047497 mitochondrion transport along microtubule 1/580 26/18722 0.559024238606875 0.671666683999115 ARMCX3 1 GO:0051016 barbed-end actin filament capping 1/580 26/18722 0.559024238606875 0.671666683999115 TRIOBP 1 GO:0051875 pigment granule localization 1/580 26/18722 0.559024238606875 0.671666683999115 RAB11A 1 GO:0060219 camera-type eye photoreceptor cell differentiation 1/580 26/18722 0.559024238606875 0.671666683999115 NAGLU 1 GO:0060544 regulation of necroptotic process 1/580 26/18722 0.559024238606875 0.671666683999115 CAV1 1 GO:0070102 interleukin-6-mediated signaling pathway 1/580 26/18722 0.559024238606875 0.671666683999115 IL6ST 1 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA 1/580 26/18722 0.559024238606875 0.671666683999115 EGFR 1 GO:0070977 bone maturation 1/580 26/18722 0.559024238606875 0.671666683999115 RHOA 1 GO:0071425 hematopoietic stem cell proliferation 1/580 26/18722 0.559024238606875 0.671666683999115 N4BP2L2 1 GO:0072273 metanephric nephron morphogenesis 1/580 26/18722 0.559024238606875 0.671666683999115 LGR4 1 GO:0097066 response to thyroid hormone 1/580 26/18722 0.559024238606875 0.671666683999115 CTSL 1 GO:0097186 amelogenesis 1/580 26/18722 0.559024238606875 0.671666683999115 CSF3R 1 GO:1901071 glucosamine-containing compound metabolic process 1/580 26/18722 0.559024238606875 0.671666683999115 EXTL2 1 GO:1902186 regulation of viral release from host cell 1/580 26/18722 0.559024238606875 0.671666683999115 DDB1 1 GO:1904353 regulation of telomere capping 1/580 26/18722 0.559024238606875 0.671666683999115 HNRNPD 1 GO:0002042 cell migration involved in sprouting angiogenesis 3/580 94/18722 0.560657465935013 0.673455029458612 ITGB1/EPHB4/RHOA 3 GO:0002831 regulation of response to biotic stimulus 10/580 327/18722 0.56168147426014 0.674510853804263 GRN/CADM1/PRKDC/PUM1/EIF2AK4/CD55/SERPINB9/HMGB1/HMGB2/CYBA 10 GO:0030199 collagen fibril organization 2/580 61/18722 0.567738219092181 0.680175810829545 COL14A1/SERPINH1 2 GO:0060997 dendritic spine morphogenesis 2/580 61/18722 0.567738219092181 0.680175810829545 CFL1/CDC42 2 GO:2000401 regulation of lymphocyte migration 2/580 61/18722 0.567738219092181 0.680175810829545 APP/RHOA 2 GO:0071356 cellular response to tumor necrosis factor 7/580 229/18722 0.567759795532564 0.680175810829545 HSPA1A/ZFP36L1/SPPL2A/TMSB4X/KRT8/NFKBIA/CYBA 7 GO:0071695 anatomical structure maturation 7/580 229/18722 0.567759795532564 0.680175810829545 DAG1/APP/DDIT3/FERMT1/ATP6AP2/TYMS/RHOA 7 GO:0002532 production of molecular mediator involved in inflammatory response 3/580 95/18722 0.567861249935739 0.680175810829545 GRN/PLD3/CHID1 3 GO:0032479 regulation of type I interferon production 3/580 95/18722 0.567861249935739 0.680175810829545 GAPDH/HMGB1/HMGB2 3 GO:0032606 type I interferon production 3/580 95/18722 0.567861249935739 0.680175810829545 GAPDH/HMGB1/HMGB2 3 GO:0045666 positive regulation of neuron differentiation 3/580 95/18722 0.567861249935739 0.680175810829545 EIF4G1/BMP7/RHOA 3 GO:0048709 oligodendrocyte differentiation 3/580 95/18722 0.567861249935739 0.680175810829545 DAG1/NCSTN/GLI3 3 GO:0061025 membrane fusion 5/580 163/18722 0.571839027737937 0.681763136275358 CTSL/SPESP1/FOLR1/KIF5B/VAMP2 5 GO:0000469 cleavage involved in rRNA processing 1/580 27/18722 0.57270448794406 0.681763136275358 RPS21 1 GO:0007263 nitric oxide mediated signal transduction 1/580 27/18722 0.57270448794406 0.681763136275358 EGFR 1 GO:0008053 mitochondrial fusion 1/580 27/18722 0.57270448794406 0.681763136275358 TFRC 1 GO:0009651 response to salt stress 1/580 27/18722 0.57270448794406 0.681763136275358 ZFP36L1 1 GO:0010586 miRNA metabolic process 1/580 27/18722 0.57270448794406 0.681763136275358 KCNQ1OT1 1 GO:0010758 regulation of macrophage chemotaxis 1/580 27/18722 0.57270448794406 0.681763136275358 MIF 1 GO:0016556 mRNA modification 1/580 27/18722 0.57270448794406 0.681763136275358 ZC3H13 1 GO:0018904 ether metabolic process 1/580 27/18722 0.57270448794406 0.681763136275358 TXN 1 GO:0032786 positive regulation of DNA-templated transcription, elongation 1/580 27/18722 0.57270448794406 0.681763136275358 BRD4 1 GO:0034505 tooth mineralization 1/580 27/18722 0.57270448794406 0.681763136275358 TFAP2A 1 GO:0035235 ionotropic glutamate receptor signaling pathway 1/580 27/18722 0.57270448794406 0.681763136275358 APP 1 GO:0039529 RIG-I signaling pathway 1/580 27/18722 0.57270448794406 0.681763136275358 PUM1 1 GO:0042745 circadian sleep/wake cycle 1/580 27/18722 0.57270448794406 0.681763136275358 ADRB1 1 GO:0045606 positive regulation of epidermal cell differentiation 1/580 27/18722 0.57270448794406 0.681763136275358 NCOA3 1 GO:0045830 positive regulation of isotype switching 1/580 27/18722 0.57270448794406 0.681763136275358 TFRC 1 GO:0046174 polyol catabolic process 1/580 27/18722 0.57270448794406 0.681763136275358 TPI1 1 GO:0046337 phosphatidylethanolamine metabolic process 1/580 27/18722 0.57270448794406 0.681763136275358 PISD 1 GO:0048520 positive regulation of behavior 1/580 27/18722 0.57270448794406 0.681763136275358 GJA1 1 GO:0060512 prostate gland morphogenesis 1/580 27/18722 0.57270448794406 0.681763136275358 BMP7 1 GO:1900746 regulation of vascular endothelial growth factor signaling pathway 1/580 27/18722 0.57270448794406 0.681763136275358 SEMA6A 1 GO:1901018 positive regulation of potassium ion transmembrane transporter activity 1/580 27/18722 0.57270448794406 0.681763136275358 AKAP9 1 GO:1902914 regulation of protein polyubiquitination 1/580 27/18722 0.57270448794406 0.681763136275358 PPIA 1 GO:2000463 positive regulation of excitatory postsynaptic potential 1/580 27/18722 0.57270448794406 0.681763136275358 PRKCZ 1 GO:0002718 regulation of cytokine production involved in immune response 3/580 96/18722 0.574992006835191 0.683961080253318 CD81/CD55/PRKCZ 3 GO:1901655 cellular response to ketone 3/580 96/18722 0.574992006835191 0.683961080253318 ATP2B1/EGFR/SERPINF1 3 GO:1904035 regulation of epithelial cell apoptotic process 3/580 96/18722 0.574992006835191 0.683961080253318 ZFP36L1/TCF7L2/SRSF6 3 GO:0016570 histone modification 14/580 463/18722 0.575384402948633 0.683966178368735 UFL1/ISL1/DDB1/ATRX/KDM5A/KMT2C/BRD4/NSD1/NIPBL/NCOA3/IGF2/CDK1/MORF4L2/FBL 14 GO:0006352 DNA-templated transcription, initiation 4/580 130/18722 0.575679283068788 0.683966178368735 JUN/BDP1/RSF1/HMGB1 4 GO:0002260 lymphocyte homeostasis 2/580 62/18722 0.576613929345046 0.683966178368735 RPS6/PMAIP1 2 GO:0007062 sister chromatid cohesion 2/580 62/18722 0.576613929345046 0.683966178368735 ATRX/NIPBL 2 GO:0007588 excretion 2/580 62/18722 0.576613929345046 0.683966178368735 NFAT5/GNAI2 2 GO:0031124 mRNA 3'-end processing 2/580 62/18722 0.576613929345046 0.683966178368735 APP/ZFP36L1 2 GO:0032615 interleukin-12 production 2/580 62/18722 0.576613929345046 0.683966178368735 ISL1/HMGB1 2 GO:0032655 regulation of interleukin-12 production 2/580 62/18722 0.576613929345046 0.683966178368735 ISL1/HMGB1 2 GO:0045428 regulation of nitric oxide biosynthetic process 2/580 62/18722 0.576613929345046 0.683966178368735 CAV1/DYNLL1 2 GO:0046173 polyol biosynthetic process 2/580 62/18722 0.576613929345046 0.683966178368735 ISYNA1/PGP 2 GO:0046847 filopodium assembly 2/580 62/18722 0.576613929345046 0.683966178368735 ITGB4/CDC42 2 GO:0019216 regulation of lipid metabolic process 10/580 331/18722 0.577204368461108 0.684491972899698 EGR1/PSAP/SF1/ADM/POR/CD81/ORMDL1/CAV1/ACADVL/CDC42 10 GO:0050864 regulation of B cell activation 6/580 198/18722 0.579329866776623 0.68682258215609 SLC39A10/ZFP36L1/TFRC/CD81/MIF/XBP1 6 GO:0006869 lipid transport 12/580 398/18722 0.579465020937539 0.68682258215609 LRP1/ITGAV/KCNN4/SLC2A1/PSAP/SLC27A2/LRP10/ATP10D/CROT/CAV1/PLIN2/NFKBIA 12 GO:0018022 peptidyl-lysine methylation 4/580 131/18722 0.58175611953499 0.68820829190062 ATRX/KMT2C/BRD4/NSD1 4 GO:0045089 positive regulation of innate immune response 4/580 131/18722 0.58175611953499 0.68820829190062 CADM1/PRKDC/HMGB1/HMGB2 4 GO:0006721 terpenoid metabolic process 3/580 97/18722 0.582048883977133 0.68820829190062 LRP2/LRP1/EGFR 3 GO:0043255 regulation of carbohydrate biosynthetic process 3/580 97/18722 0.582048883977133 0.68820829190062 DDB1/PGP/IGF2 3 GO:0032635 interleukin-6 production 5/580 165/18722 0.582707998770216 0.68820829190062 APP/ISL1/XBP1/HMGB1/CYBA 5 GO:0032675 regulation of interleukin-6 production 5/580 165/18722 0.582707998770216 0.68820829190062 APP/ISL1/XBP1/HMGB1/CYBA 5 GO:0099601 regulation of neurotransmitter receptor activity 2/580 63/18722 0.585355707807894 0.68820829190062 AKAP9/APP 2 GO:2000756 regulation of peptidyl-lysine acetylation 2/580 63/18722 0.585355707807894 0.68820829190062 SOX4/ISL1 2 GO:0000423 mitophagy 1/580 28/18722 0.58596104836088 0.68820829190062 VDAC1 1 GO:0000470 maturation of LSU-rRNA 1/580 28/18722 0.58596104836088 0.68820829190062 RPL7 1 GO:0002313 mature B cell differentiation involved in immune response 1/580 28/18722 0.58596104836088 0.68820829190062 XBP1 1 GO:0002507 tolerance induction 1/580 28/18722 0.58596104836088 0.68820829190062 HMGB1 1 GO:0002675 positive regulation of acute inflammatory response 1/580 28/18722 0.58596104836088 0.68820829190062 IL6ST 1 GO:0006972 hyperosmotic response 1/580 28/18722 0.58596104836088 0.68820829190062 SLC2A1 1 GO:0007141 male meiosis I 1/580 28/18722 0.58596104836088 0.68820829190062 SLC2A8 1 GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway 1/580 28/18722 0.58596104836088 0.68820829190062 LRP1 1 GO:0008299 isoprenoid biosynthetic process 1/580 28/18722 0.58596104836088 0.68820829190062 HMGCR 1 GO:0009312 oligosaccharide biosynthetic process 1/580 28/18722 0.58596104836088 0.68820829190062 MPDU1 1 GO:0010464 regulation of mesenchymal cell proliferation 1/580 28/18722 0.58596104836088 0.68820829190062 LRP5 1 GO:0010818 T cell chemotaxis 1/580 28/18722 0.58596104836088 0.68820829190062 PLEC 1 GO:0010884 positive regulation of lipid storage 1/580 28/18722 0.58596104836088 0.68820829190062 PLIN2 1 GO:0015740 C4-dicarboxylate transport 1/580 28/18722 0.58596104836088 0.68820829190062 SLC1A5 1 GO:0019098 reproductive behavior 1/580 28/18722 0.58596104836088 0.68820829190062 APP 1 GO:0031342 negative regulation of cell killing 1/580 28/18722 0.58596104836088 0.68820829190062 SERPINB9 1 GO:0031440 regulation of mRNA 3'-end processing 1/580 28/18722 0.58596104836088 0.68820829190062 ZFP36L1 1 GO:0032607 interferon-alpha production 1/580 28/18722 0.58596104836088 0.68820829190062 HMGB1 1 GO:0032647 regulation of interferon-alpha production 1/580 28/18722 0.58596104836088 0.68820829190062 HMGB1 1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 1/580 28/18722 0.58596104836088 0.68820829190062 EGFR 1 GO:0044331 cell-cell adhesion mediated by cadherin 1/580 28/18722 0.58596104836088 0.68820829190062 CTNND1 1 GO:0045589 regulation of regulatory T cell differentiation 1/580 28/18722 0.58596104836088 0.68820829190062 CD46 1 GO:0045671 negative regulation of osteoclast differentiation 1/580 28/18722 0.58596104836088 0.68820829190062 FBN1 1 GO:0060259 regulation of feeding behavior 1/580 28/18722 0.58596104836088 0.68820829190062 EIF2AK4 1 GO:0070076 histone lysine demethylation 1/580 28/18722 0.58596104836088 0.68820829190062 KDM5A 1 GO:0071280 cellular response to copper ion 1/580 28/18722 0.58596104836088 0.68820829190062 APP 1 GO:0090200 positive regulation of release of cytochrome c from mitochondria 1/580 28/18722 0.58596104836088 0.68820829190062 PMAIP1 1 GO:1903671 negative regulation of sprouting angiogenesis 1/580 28/18722 0.58596104836088 0.68820829190062 SEMA6A 1 GO:0002367 cytokine production involved in immune response 3/580 98/18722 0.589031103297404 0.691445941552938 CD81/CD55/PRKCZ 3 GO:0043473 pigmentation 3/580 98/18722 0.589031103297404 0.691445941552938 GLI3/ATP6AP2/RAB11A 3 GO:0099003 vesicle-mediated transport in synapse 6/580 200/18722 0.589163677999203 0.691445941552938 ROCK1/CALM1/VAMP2/ACTG1/CANX/RAB11A 6 GO:0010565 regulation of cellular ketone metabolic process 4/580 133/18722 0.593758345243627 0.695301323125987 EGR1/ADM/CAV1/ACADVL 4 GO:0017156 calcium-ion regulated exocytosis 2/580 64/18722 0.593963320905065 0.695301323125987 VAMP2/GNAI2 2 GO:0030858 positive regulation of epithelial cell differentiation 2/580 64/18722 0.593963320905065 0.695301323125987 BTG1/NCOA3 2 GO:0046530 photoreceptor cell differentiation 2/580 64/18722 0.593963320905065 0.695301323125987 NAGLU/TUG1 2 GO:0046579 positive regulation of Ras protein signal transduction 2/580 64/18722 0.593963320905065 0.695301323125987 ADGRG1/DYNLT1 2 GO:0046888 negative regulation of hormone secretion 2/580 64/18722 0.593963320905065 0.695301323125987 GJA1/HMGCR 2 GO:0080164 regulation of nitric oxide metabolic process 2/580 64/18722 0.593963320905065 0.695301323125987 CAV1/DYNLL1 2 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process 2/580 64/18722 0.593963320905065 0.695301323125987 RPL23/EIF3H 2 GO:1903409 reactive oxygen species biosynthetic process 2/580 64/18722 0.593963320905065 0.695301323125987 RHOA/CYBA 2 GO:0002699 positive regulation of immune effector process 7/580 235/18722 0.595171096927812 0.695301323125987 CD46/CADM1/TFRC/CD81/XBP1/CD55/PRKCZ 7 GO:0003300 cardiac muscle hypertrophy 3/580 99/18722 0.595937959025199 0.695301323125987 SLC9A1/ROCK1/IL6ST 3 GO:0007631 feeding behavior 3/580 99/18722 0.595937959025199 0.695301323125987 FOS/APP/EIF2AK4 3 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 3/580 99/18722 0.595937959025199 0.695301323125987 TPT1/PRKDC/MIF 3 GO:0015837 amine transport 3/580 99/18722 0.595937959025199 0.695301323125987 ITGB1/SLC43A2/ARL6IP5 3 GO:0031341 regulation of cell killing 3/580 99/18722 0.595937959025199 0.695301323125987 CADM1/CD55/SERPINB9 3 GO:0051153 regulation of striated muscle cell differentiation 3/580 99/18722 0.595937959025199 0.695301323125987 YBX1/XBP1/MORF4L2 3 GO:0060996 dendritic spine development 3/580 99/18722 0.595937959025199 0.695301323125987 DLG5/CFL1/CDC42 3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 1/580 29/18722 0.598807019899914 0.695301323125987 TNRC6A 1 GO:0002068 glandular epithelial cell development 1/580 29/18722 0.598807019899914 0.695301323125987 CDK6 1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus 1/580 29/18722 0.598807019899914 0.695301323125987 GPX1 1 GO:0003309 type B pancreatic cell differentiation 1/580 29/18722 0.598807019899914 0.695301323125987 CDK6 1 GO:0005979 regulation of glycogen biosynthetic process 1/580 29/18722 0.598807019899914 0.695301323125987 IGF2 1 GO:0006734 NADH metabolic process 1/580 29/18722 0.598807019899914 0.695301323125987 ENO1 1 GO:0010390 histone monoubiquitination 1/580 29/18722 0.598807019899914 0.695301323125987 DDB1 1 GO:0010962 regulation of glucan biosynthetic process 1/580 29/18722 0.598807019899914 0.695301323125987 IGF2 1 GO:0015701 bicarbonate transport 1/580 29/18722 0.598807019899914 0.695301323125987 SLC26A2 1 GO:0033028 myeloid cell apoptotic process 1/580 29/18722 0.598807019899914 0.695301323125987 CTSL 1 GO:0034067 protein localization to Golgi apparatus 1/580 29/18722 0.598807019899914 0.695301323125987 GCC2 1 GO:0034311 diol metabolic process 1/580 29/18722 0.598807019899914 0.695301323125987 PLPP3 1 GO:0035066 positive regulation of histone acetylation 1/580 29/18722 0.598807019899914 0.695301323125987 ISL1 1 GO:0043153 entrainment of circadian clock by photoperiod 1/580 29/18722 0.598807019899914 0.695301323125987 NR2F6 1 GO:0048265 response to pain 1/580 29/18722 0.598807019899914 0.695301323125987 VWA1 1 GO:0051654 establishment of mitochondrion localization 1/580 29/18722 0.598807019899914 0.695301323125987 ARMCX3 1 GO:0051873 killing by host of symbiont cells 1/580 29/18722 0.598807019899914 0.695301323125987 GAPDH 1 GO:0051883 killing of cells in other organism involved in symbiotic interaction 1/580 29/18722 0.598807019899914 0.695301323125987 GAPDH 1 GO:0062098 regulation of programmed necrotic cell death 1/580 29/18722 0.598807019899914 0.695301323125987 CAV1 1 GO:0070198 protein localization to chromosome, telomeric region 1/580 29/18722 0.598807019899914 0.695301323125987 ATRX 1 GO:0098868 bone growth 1/580 29/18722 0.598807019899914 0.695301323125987 POR 1 GO:1901017 negative regulation of potassium ion transmembrane transporter activity 1/580 29/18722 0.598807019899914 0.695301323125987 CAV1 1 GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1/580 29/18722 0.598807019899914 0.695301323125987 MIF 1 GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus 1/580 29/18722 0.598807019899914 0.695301323125987 SEMA6A 1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining 1/580 29/18722 0.598807019899914 0.695301323125987 PRKDC 1 GO:0019722 calcium-mediated signaling 6/580 202/18722 0.598877037291487 0.695301323125987 EGFR/NFAT5/SLC9A1/CALM1/GSTO1/CALM2 6 GO:0046395 carboxylic acid catabolic process 7/580 236/18722 0.599653450317664 0.696028998609298 GLDC/ILVBL/SLC27A2/CROT/ECHDC2/ACADVL/HADHA 7 GO:0046513 ceramide biosynthetic process 2/580 65/18722 0.602436677809714 0.698947334945501 ORMDL1/DEGS1 2 GO:0006626 protein targeting to mitochondrion 3/580 100/18722 0.602768815408816 0.698947334945501 LMAN1/LEPROT/UBE2L3 3 GO:0044728 DNA methylation or demethylation 3/580 100/18722 0.602768815408816 0.698947334945501 FOS/ATRX/MPHOSPH8 3 GO:0045807 positive regulation of endocytosis 3/580 100/18722 0.602768815408816 0.698947334945501 LRP1/GPC3/CDC42 3 GO:0009152 purine ribonucleotide biosynthetic process 5/580 169/18722 0.603992570543748 0.699979176852353 SLC26A2/ALDOA/ENO1/ACSS1/TMSB4X 5 GO:0018394 peptidyl-lysine acetylation 5/580 169/18722 0.603992570543748 0.699979176852353 SOX4/ISL1/POR/NCOA3/MORF4L2 5 GO:1901617 organic hydroxy compound biosynthetic process 7/580 237/18722 0.604110173271414 0.699979176852353 DHCR24/ISYNA1/HMGCR/SLC27A2/POR/HSD17B1/PGP 7 GO:0051259 protein complex oligomerization 7/580 238/18722 0.608540916978848 0.703525726781957 ALDOA/SLC1A5/SLC9A1/FUS/MIF/NINJ1/RRM2 7 GO:0006476 protein deacetylation 3/580 101/18722 0.609523104467971 0.703525726781957 KDM5A/NIPBL/MORF4L2 3 GO:0042093 T-helper cell differentiation 2/580 66/18722 0.610775821852621 0.703525726781957 PRKCZ/HMGB1 2 GO:0071300 cellular response to retinoic acid 2/580 66/18722 0.610775821852621 0.703525726781957 SERPINF1/SLC6A4 2 GO:1905953 negative regulation of lipid localization 2/580 66/18722 0.610775821852621 0.703525726781957 ITGAV/NFKBIA 2 GO:0007176 regulation of epidermal growth factor-activated receptor activity 1/580 30/18722 0.611255098242504 0.703525726781957 APP 1 GO:0008209 androgen metabolic process 1/580 30/18722 0.611255098242504 0.703525726781957 ADM 1 GO:0009264 deoxyribonucleotide catabolic process 1/580 30/18722 0.611255098242504 0.703525726781957 DUT 1 GO:0010453 regulation of cell fate commitment 1/580 30/18722 0.611255098242504 0.703525726781957 LMO4 1 GO:0017145 stem cell division 1/580 30/18722 0.611255098242504 0.703525726781957 NCOA3 1 GO:0031365 N-terminal protein amino acid modification 1/580 30/18722 0.611255098242504 0.703525726781957 SOX4 1 GO:0033137 negative regulation of peptidyl-serine phosphorylation 1/580 30/18722 0.611255098242504 0.703525726781957 CAV1 1 GO:0034694 response to prostaglandin 1/580 30/18722 0.611255098242504 0.703525726781957 TGFBR3 1 GO:0036258 multivesicular body assembly 1/580 30/18722 0.611255098242504 0.703525726781957 RAB11A 1 GO:0044030 regulation of DNA methylation 1/580 30/18722 0.611255098242504 0.703525726781957 MPHOSPH8 1 GO:0048147 negative regulation of fibroblast proliferation 1/580 30/18722 0.611255098242504 0.703525726781957 FTH1 1 GO:0048799 animal organ maturation 1/580 30/18722 0.611255098242504 0.703525726781957 RHOA 1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway 1/580 30/18722 0.611255098242504 0.703525726781957 PHPT1 1 GO:0051125 regulation of actin nucleation 1/580 30/18722 0.611255098242504 0.703525726781957 WASF2 1 GO:0051491 positive regulation of filopodium assembly 1/580 30/18722 0.611255098242504 0.703525726781957 CDC42 1 GO:0051968 positive regulation of synaptic transmission, glutamatergic 1/580 30/18722 0.611255098242504 0.703525726781957 EGFR 1 GO:0061311 cell surface receptor signaling pathway involved in heart development 1/580 30/18722 0.611255098242504 0.703525726781957 GALNT11 1 GO:0070168 negative regulation of biomineral tissue development 1/580 30/18722 0.611255098242504 0.703525726781957 ROCK1 1 GO:0070229 negative regulation of lymphocyte apoptotic process 1/580 30/18722 0.611255098242504 0.703525726781957 SLC39A10 1 GO:0070498 interleukin-1-mediated signaling pathway 1/580 30/18722 0.611255098242504 0.703525726781957 EGR1 1 GO:0090151 establishment of protein localization to mitochondrial membrane 1/580 30/18722 0.611255098242504 0.703525726781957 CALM1 1 GO:1903579 negative regulation of ATP metabolic process 1/580 30/18722 0.611255098242504 0.703525726781957 RHOA 1 GO:0014897 striated muscle hypertrophy 3/580 102/18722 0.616200323774575 0.709041985619879 SLC9A1/ROCK1/IL6ST 3 GO:0034754 cellular hormone metabolic process 4/580 137/18722 0.61714002590823 0.709772072329174 EGR1/ADM/HSD17B1/DHRS2 4 GO:0060078 regulation of postsynaptic membrane potential 4/580 137/18722 0.61714002590823 0.709772072329174 APP/GABRE/ADRB1/PRKCZ 4 GO:0016054 organic acid catabolic process 7/580 240/18722 0.61732313108177 0.709807140336542 GLDC/ILVBL/SLC27A2/CROT/ECHDC2/ACADVL/HADHA 7 GO:0016445 somatic diversification of immunoglobulins 2/580 67/18722 0.618980922324737 0.711361568997369 PRKDC/TFRC 2 GO:1902117 positive regulation of organelle assembly 2/580 67/18722 0.618980922324737 0.711361568997369 DYNC1H1/RHOA 2 GO:0044282 small molecule catabolic process 11/580 376/18722 0.619580880643417 0.71159796218074 ENO1/GLDC/LRP5/ILVBL/SLC27A2/MGAT1/TPI1/CROT/ECHDC2/ACADVL/HADHA 11 GO:0007224 smoothened signaling pathway 4/580 138/18722 0.622852610987614 0.71159796218074 GLI3/DLG5/POR/GPC3 4 GO:0002063 chondrocyte development 1/580 31/18722 0.623317587169283 0.71159796218074 SERPINH1 1 GO:0002230 positive regulation of defense response to virus by host 1/580 31/18722 0.623317587169283 0.71159796218074 EIF2AK4 1 GO:0002717 positive regulation of natural killer cell mediated immunity 1/580 31/18722 0.623317587169283 0.71159796218074 CADM1 1 GO:0006301 postreplication repair 1/580 31/18722 0.623317587169283 0.71159796218074 PCNA 1 GO:0008045 motor neuron axon guidance 1/580 31/18722 0.623317587169283 0.71159796218074 MYCBP2 1 GO:0016577 histone demethylation 1/580 31/18722 0.623317587169283 0.71159796218074 KDM5A 1 GO:0030212 hyaluronan metabolic process 1/580 31/18722 0.623317587169283 0.71159796218074 ITIH5 1 GO:0032509 endosome transport via multivesicular body sorting pathway 1/580 31/18722 0.623317587169283 0.71159796218074 LEPROT 1 GO:0034656 nucleobase-containing small molecule catabolic process 1/580 31/18722 0.623317587169283 0.71159796218074 MGAT1 1 GO:0036257 multivesicular body organization 1/580 31/18722 0.623317587169283 0.71159796218074 RAB11A 1 GO:0036475 neuron death in response to oxidative stress 1/580 31/18722 0.623317587169283 0.71159796218074 ARL6IP5 1 GO:0042133 neurotransmitter metabolic process 1/580 31/18722 0.623317587169283 0.71159796218074 SLC6A4 1 GO:0043171 peptide catabolic process 1/580 31/18722 0.623317587169283 0.71159796218074 ENPEP 1 GO:0045066 regulatory T cell differentiation 1/580 31/18722 0.623317587169283 0.71159796218074 CD46 1 GO:0045987 positive regulation of smooth muscle contraction 1/580 31/18722 0.623317587169283 0.71159796218074 RHOA 1 GO:0046386 deoxyribose phosphate catabolic process 1/580 31/18722 0.623317587169283 0.71159796218074 DUT 1 GO:0048710 regulation of astrocyte differentiation 1/580 31/18722 0.623317587169283 0.71159796218074 IL6ST 1 GO:0051443 positive regulation of ubiquitin-protein transferase activity 1/580 31/18722 0.623317587169283 0.71159796218074 UBE2L3 1 GO:0055075 potassium ion homeostasis 1/580 31/18722 0.623317587169283 0.71159796218074 SLC12A9 1 GO:0061099 negative regulation of protein tyrosine kinase activity 1/580 31/18722 0.623317587169283 0.71159796218074 CAV1 1 GO:0070633 transepithelial transport 1/580 31/18722 0.623317587169283 0.71159796218074 ACTG1 1 GO:0071168 protein localization to chromatin 1/580 31/18722 0.623317587169283 0.71159796218074 NIPBL 1 GO:0110150 negative regulation of biomineralization 1/580 31/18722 0.623317587169283 0.71159796218074 ROCK1 1 GO:1901797 negative regulation of signal transduction by p53 class mediator 1/580 31/18722 0.623317587169283 0.71159796218074 MIF 1 GO:2000144 positive regulation of DNA-templated transcription, initiation 1/580 31/18722 0.623317587169283 0.71159796218074 JUN 1 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 2/580 68/18722 0.627052266657402 0.715159414473657 PRKCZ/HMGB1 2 GO:0007585 respiratory gaseous exchange by respiratory system 2/580 68/18722 0.627052266657402 0.715159414473657 GAA/MAN1A2 2 GO:0031640 killing of cells of other organism 2/580 68/18722 0.627052266657402 0.715159414473657 GAPDH/SERPINB9 2 GO:0061912 selective autophagy 2/580 68/18722 0.627052266657402 0.715159414473657 UFL1/VDAC1 2 GO:0006836 neurotransmitter transport 6/580 208/18722 0.627261123513285 0.71522223227759 ITGB1/SLC38A2/SLC38A1/CALM1/SLC6A4/VAMP2 6 GO:0002287 alpha-beta T cell activation involved in immune response 2/580 69/18722 0.634990252964762 0.720520813826387 PRKCZ/HMGB1 2 GO:0002293 alpha-beta T cell differentiation involved in immune response 2/580 69/18722 0.634990252964762 0.720520813826387 PRKCZ/HMGB1 2 GO:0006368 transcription elongation from RNA polymerase II promoter 2/580 69/18722 0.634990252964762 0.720520813826387 SERTAD1/BRD4 2 GO:0019226 transmission of nerve impulse 2/580 69/18722 0.634990252964762 0.720520813826387 PLEC/JAM3 2 GO:0050805 negative regulation of synaptic transmission 2/580 69/18722 0.634990252964762 0.720520813826387 SLC6A4/GNAI2 2 GO:0003180 aortic valve morphogenesis 1/580 32/18722 0.635006410637359 0.720520813826387 ROCK1 1 GO:0006506 GPI anchor biosynthetic process 1/580 32/18722 0.635006410637359 0.720520813826387 GPAA1 1 GO:0008156 negative regulation of DNA replication 1/580 32/18722 0.635006410637359 0.720520813826387 GMNN 1 GO:0010039 response to iron ion 1/580 32/18722 0.635006410637359 0.720520813826387 TFAP2A 1 GO:0010667 negative regulation of cardiac muscle cell apoptotic process 1/580 32/18722 0.635006410637359 0.720520813826387 PPP1R10 1 GO:0019835 cytolysis 1/580 32/18722 0.635006410637359 0.720520813826387 NINJ1 1 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter 1/580 32/18722 0.635006410637359 0.720520813826387 BRD4 1 GO:0035883 enteroendocrine cell differentiation 1/580 32/18722 0.635006410637359 0.720520813826387 CDK6 1 GO:0042219 cellular modified amino acid catabolic process 1/580 32/18722 0.635006410637359 0.720520813826387 PCYOX1 1 GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 1/580 32/18722 0.635006410637359 0.720520813826387 PRKCZ 1 GO:0045684 positive regulation of epidermis development 1/580 32/18722 0.635006410637359 0.720520813826387 NCOA3 1 GO:0050850 positive regulation of calcium-mediated signaling 1/580 32/18722 0.635006410637359 0.720520813826387 SLC9A1 1 GO:0061037 negative regulation of cartilage development 1/580 32/18722 0.635006410637359 0.720520813826387 EFEMP1 1 GO:0097345 mitochondrial outer membrane permeabilization 1/580 32/18722 0.635006410637359 0.720520813826387 HSPA1A 1 GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 1/580 32/18722 0.635006410637359 0.720520813826387 HMGB1 1 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 3/580 105/18722 0.635765476435524 0.721206153878444 WASF2/PFN1/CDC42 3 GO:0030183 B cell differentiation 4/580 141/18722 0.639664544556355 0.725275425824381 ITGB1/ZFP36L1/PRKDC/XBP1 4 GO:0048284 organelle fusion 4/580 141/18722 0.639664544556355 0.725275425824381 KIF5B/TFRC/VAMP2/CDK1 4 GO:0043087 regulation of GTPase activity 10/580 348/18722 0.640292759170366 0.725810778187028 ITGA6/IQGAP2/ITGB1/MET/IQGAP1/ADRB1/RASA1/STMN1/RGS10/DYNLT1 10 GO:0021700 developmental maturation 8/580 280/18722 0.641488648715004 0.726989206913617 DAG1/APP/DDIT3/FERMT1/ATP6AP2/PFN1/TYMS/RHOA 8 GO:0002335 mature B cell differentiation 1/580 33/18722 0.64633312448596 0.728397228491446 XBP1 1 GO:0006336 DNA replication-independent nucleosome assembly 1/580 33/18722 0.64633312448596 0.728397228491446 ATRX 1 GO:0006482 protein demethylation 1/580 33/18722 0.64633312448596 0.728397228491446 KDM5A 1 GO:0006505 GPI anchor metabolic process 1/580 33/18722 0.64633312448596 0.728397228491446 GPAA1 1 GO:0008214 protein dealkylation 1/580 33/18722 0.64633312448596 0.728397228491446 KDM5A 1 GO:0009648 photoperiodism 1/580 33/18722 0.64633312448596 0.728397228491446 NR2F6 1 GO:0010165 response to X-ray 1/580 33/18722 0.64633312448596 0.728397228491446 NIPBL 1 GO:0010259 multicellular organism aging 1/580 33/18722 0.64633312448596 0.728397228491446 CTSV 1 GO:0010737 protein kinase A signaling 1/580 33/18722 0.64633312448596 0.728397228491446 MIF 1 GO:0032228 regulation of synaptic transmission, GABAergic 1/580 33/18722 0.64633312448596 0.728397228491446 KIF5B 1 GO:0033198 response to ATP 1/580 33/18722 0.64633312448596 0.728397228491446 HSP90B1 1 GO:0034110 regulation of homotypic cell-cell adhesion 1/580 33/18722 0.64633312448596 0.728397228491446 IL6ST 1 GO:0035025 positive regulation of Rho protein signal transduction 1/580 33/18722 0.64633312448596 0.728397228491446 ADGRG1 1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 1/580 33/18722 0.64633312448596 0.728397228491446 CDC42 1 GO:0045920 negative regulation of exocytosis 1/580 33/18722 0.64633312448596 0.728397228491446 GNAI2 1 GO:0046320 regulation of fatty acid oxidation 1/580 33/18722 0.64633312448596 0.728397228491446 ACADVL 1 GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 1/580 33/18722 0.64633312448596 0.728397228491446 HMGB1 1 GO:0071539 protein localization to centrosome 1/580 33/18722 0.64633312448596 0.728397228491446 GOLGB1 1 GO:1901099 negative regulation of signal transduction in absence of ligand 1/580 33/18722 0.64633312448596 0.728397228491446 HSPA1A 1 GO:1901380 negative regulation of potassium ion transmembrane transport 1/580 33/18722 0.64633312448596 0.728397228491446 CAV1 1 GO:1903146 regulation of autophagy of mitochondrion 1/580 33/18722 0.64633312448596 0.728397228491446 VDAC1 1 GO:1903715 regulation of aerobic respiration 1/580 33/18722 0.64633312448596 0.728397228491446 RHOA 1 GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 1/580 33/18722 0.64633312448596 0.728397228491446 HSPA1A 1 GO:0022412 cellular process involved in reproduction in multicellular organism 11/580 384/18722 0.647074089209122 0.729055617468902 LGR5/RPS6/ITGB1/SPESP1/SLC2A8/FOLR1/JAM3/ASPM/EIF2S2/DYNLL1/HMGB2 11 GO:0002449 lymphocyte mediated immunity 10/580 350/18722 0.64737479633209 0.729217771310378 CD46/CADM1/CTSC/KIF5B/TFRC/CD81/CD55/PRKCZ/SERPINB9/HMGB1 10 GO:0043414 macromolecule methylation 9/580 316/18722 0.648082689379473 0.729838399105067 FOS/ZC3H13/BTG1/ATRX/KMT2C/BRD4/NSD1/MPHOSPH8/FBL 9 GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 3/580 107/18722 0.648417104589651 0.730038236128411 HSPA1A/HECTD1/CAV1 3 GO:0048015 phosphatidylinositol-mediated signaling 5/580 178/18722 0.649534896142625 0.731119748780094 EGFR/ZFP36L1/ERBB3/IGF1R/MYDGF 5 GO:0008344 adult locomotory behavior 2/580 71/18722 0.650468255045657 0.731462247151197 APP/PUM1 2 GO:0043550 regulation of lipid kinase activity 2/580 71/18722 0.650468255045657 0.731462247151197 CD81/CDC42 2 GO:0045824 negative regulation of innate immune response 2/580 71/18722 0.650468255045657 0.731462247151197 GRN/SERPINB9 2 GO:0050818 regulation of coagulation 2/580 71/18722 0.650468255045657 0.731462247151197 ANXA5/CAV1 2 GO:0032102 negative regulation of response to external stimulus 12/580 420/18722 0.65352044391065 0.734716844241826 GRN/SEMA6A/SEMA6D/SERPINF1/DUSP1/ISL1/GJA1/DPP4/HMGCR/MIF/GPX1/SERPINB9 12 GO:0007416 synapse assembly 5/580 179/18722 0.654385658796964 0.735067040902547 CDH1/APP/TPBG/DLG5/EIF4G1 5 GO:0007173 epidermal growth factor receptor signaling pathway 3/580 108/18722 0.65462475360946 0.735067040902547 EGFR/EFEMP1/IQGAP1 3 GO:0098659 inorganic cation import across plasma membrane 3/580 108/18722 0.65462475360946 0.735067040902547 SLC39A10/SLC12A9/SLC9A1 3 GO:0099587 inorganic ion import across plasma membrane 3/580 108/18722 0.65462475360946 0.735067040902547 SLC39A10/SLC12A9/SLC9A1 3 GO:0006270 DNA replication initiation 1/580 34/18722 0.657308927781917 0.735067040902547 PURA 1 GO:0006356 regulation of transcription by RNA polymerase I 1/580 34/18722 0.657308927781917 0.735067040902547 NCL 1 GO:0007095 mitotic G2 DNA damage checkpoint signaling 1/580 34/18722 0.657308927781917 0.735067040902547 CDK1 1 GO:0009112 nucleobase metabolic process 1/580 34/18722 0.657308927781917 0.735067040902547 TYMS 1 GO:0009303 rRNA transcription 1/580 34/18722 0.657308927781917 0.735067040902547 NCL 1 GO:0010661 positive regulation of muscle cell apoptotic process 1/580 34/18722 0.657308927781917 0.735067040902547 HMGCR 1 GO:0014072 response to isoquinoline alkaloid 1/580 34/18722 0.657308927781917 0.735067040902547 FOSB 1 GO:0030851 granulocyte differentiation 1/580 34/18722 0.657308927781917 0.735067040902547 CITED2 1 GO:0032212 positive regulation of telomere maintenance via telomerase 1/580 34/18722 0.657308927781917 0.735067040902547 HNRNPA1 1 GO:0032743 positive regulation of interleukin-2 production 1/580 34/18722 0.657308927781917 0.735067040902547 SPTBN1 1 GO:0034724 DNA replication-independent nucleosome organization 1/580 34/18722 0.657308927781917 0.735067040902547 ATRX 1 GO:0035590 purinergic nucleotide receptor signaling pathway 1/580 34/18722 0.657308927781917 0.735067040902547 GNAI2 1 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus 1/580 34/18722 0.657308927781917 0.735067040902547 PUM1 1 GO:0043278 response to morphine 1/580 34/18722 0.657308927781917 0.735067040902547 FOSB 1 GO:0048854 brain morphogenesis 1/580 34/18722 0.657308927781917 0.735067040902547 SLC6A4 1 GO:0050931 pigment cell differentiation 1/580 34/18722 0.657308927781917 0.735067040902547 GLI3 1 GO:0051973 positive regulation of telomerase activity 1/580 34/18722 0.657308927781917 0.735067040902547 PTGES3 1 GO:0070050 neuron cellular homeostasis 1/580 34/18722 0.657308927781917 0.735067040902547 ATP2B1 1 GO:0002534 cytokine production involved in inflammatory response 2/580 72/18722 0.658009558120541 0.735496864892727 PLD3/CHID1 2 GO:1900015 regulation of cytokine production involved in inflammatory response 2/580 72/18722 0.658009558120541 0.735496864892727 PLD3/CHID1 2 GO:0007033 vacuole organization 5/580 180/18722 0.65919344058718 0.736643126422627 GRN/GAA/NAGLU/ATP6AP2/HOOK2 5 GO:0032640 tumor necrosis factor production 5/580 181/18722 0.663958009102538 0.74125508889484 APP/ISL1/MIF/HMGB1/CYBA 5 GO:0032680 regulation of tumor necrosis factor production 5/580 181/18722 0.663958009102538 0.74125508889484 APP/ISL1/MIF/HMGB1/CYBA 5 GO:0099504 synaptic vesicle cycle 5/580 181/18722 0.663958009102538 0.74125508889484 ROCK1/CALM1/VAMP2/ACTG1/CANX 5 GO:1905952 regulation of lipid localization 5/580 181/18722 0.663958009102538 0.74125508889484 LRP1/ITGAV/CAV1/PLIN2/NFKBIA 5 GO:0032456 endocytic recycling 2/580 73/18722 0.665420065162939 0.742143019091877 CMTM6/RAB11A 2 GO:0035924 cellular response to vascular endothelial growth factor stimulus 2/580 73/18722 0.665420065162939 0.742143019091877 NRP2/SEMA6A 2 GO:0051145 smooth muscle cell differentiation 2/580 73/18722 0.665420065162939 0.742143019091877 ADM/TBX3 2 GO:0070988 demethylation 2/580 73/18722 0.665420065162939 0.742143019091877 POR/KDM5A 2 GO:0048259 regulation of receptor-mediated endocytosis 3/580 110/18722 0.666803204648516 0.742143019091877 ITGAV/AAK1/LRPAP1 3 GO:1904659 glucose transmembrane transport 3/580 110/18722 0.666803204648516 0.742143019091877 SLC2A1/SLC2A8/GPC3 3 GO:0000731 DNA synthesis involved in DNA repair 1/580 35/18722 0.667944673816082 0.742143019091877 PCNA 1 GO:0006084 acetyl-CoA metabolic process 1/580 35/18722 0.667944673816082 0.742143019091877 ACSS1 1 GO:0006691 leukotriene metabolic process 1/580 35/18722 0.667944673816082 0.742143019091877 MGST3 1 GO:0008608 attachment of spindle microtubules to kinetochore 1/580 35/18722 0.667944673816082 0.742143019091877 CDC42 1 GO:0015695 organic cation transport 1/580 35/18722 0.667944673816082 0.742143019091877 SLC38A2 1 GO:0018149 peptide cross-linking 1/580 35/18722 0.667944673816082 0.742143019091877 DSP 1 GO:0021955 central nervous system neuron axonogenesis 1/580 35/18722 0.667944673816082 0.742143019091877 MYCBP2 1 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 1/580 35/18722 0.667944673816082 0.742143019091877 EIF3H 1 GO:0043243 positive regulation of protein-containing complex disassembly 1/580 35/18722 0.667944673816082 0.742143019091877 IGF1R 1 GO:0044273 sulfur compound catabolic process 1/580 35/18722 0.667944673816082 0.742143019091877 GNS 1 GO:0045922 negative regulation of fatty acid metabolic process 1/580 35/18722 0.667944673816082 0.742143019091877 ACADVL 1 GO:0046471 phosphatidylglycerol metabolic process 1/580 35/18722 0.667944673816082 0.742143019091877 HADHA 1 GO:1905207 regulation of cardiocyte differentiation 1/580 35/18722 0.667944673816082 0.742143019091877 EGFR 1 GO:1905508 protein localization to microtubule organizing center 1/580 35/18722 0.667944673816082 0.742143019091877 GOLGB1 1 GO:0009260 ribonucleotide biosynthetic process 5/580 182/18722 0.66867915179177 0.742427007635121 SLC26A2/ALDOA/ENO1/ACSS1/TMSB4X 5 GO:0048017 inositol lipid-mediated signaling 5/580 182/18722 0.66867915179177 0.742427007635121 EGFR/ZFP36L1/ERBB3/IGF1R/MYDGF 5 GO:0051260 protein homooligomerization 5/580 182/18722 0.66867915179177 0.742427007635121 ALDOA/SLC1A5/FUS/MIF/NINJ1 5 GO:0034612 response to tumor necrosis factor 7/580 253/18722 0.671683143635613 0.745584320059484 HSPA1A/ZFP36L1/SPPL2A/TMSB4X/KRT8/NFKBIA/CYBA 7 GO:0045088 regulation of innate immune response 6/580 218/18722 0.671886888734767 0.745632526725221 GRN/CADM1/PRKDC/SERPINB9/HMGB1/HMGB2 6 GO:0010822 positive regulation of mitochondrion organization 2/580 74/18722 0.672700627504464 0.746082885503144 PMAIP1/VDAC1 2 GO:0046323 glucose import 2/580 74/18722 0.672700627504464 0.746082885503144 SLC2A1/GPC3 2 GO:0006805 xenobiotic metabolic process 3/580 111/18722 0.672773945775142 0.746082885503144 POR/GSTO1/CYP2J2 3 GO:0044272 sulfur compound biosynthetic process 4/580 148/18722 0.676951737883543 0.75018902411918 SLC26A2/CHPF/CHST12/ACSS1 4 GO:0002691 regulation of cellular extravasation 1/580 36/18722 0.678250880761374 0.75018902411918 JAM3 1 GO:0006699 bile acid biosynthetic process 1/580 36/18722 0.678250880761374 0.75018902411918 SLC27A2 1 GO:0010762 regulation of fibroblast migration 1/580 36/18722 0.678250880761374 0.75018902411918 ITGB1 1 GO:0042119 neutrophil activation 1/580 36/18722 0.678250880761374 0.75018902411918 GRN 1 GO:0044060 regulation of endocrine process 1/580 36/18722 0.678250880761374 0.75018902411918 GJA1 1 GO:0045191 regulation of isotype switching 1/580 36/18722 0.678250880761374 0.75018902411918 TFRC 1 GO:0045652 regulation of megakaryocyte differentiation 1/580 36/18722 0.678250880761374 0.75018902411918 HMGB2 1 GO:0051354 negative regulation of oxidoreductase activity 1/580 36/18722 0.678250880761374 0.75018902411918 CAV1 1 GO:0086010 membrane depolarization during action potential 1/580 36/18722 0.678250880761374 0.75018902411918 YWHAH 1 GO:0097009 energy homeostasis 1/580 36/18722 0.678250880761374 0.75018902411918 EIF4G1 1 GO:0032609 interferon-gamma production 3/580 112/18722 0.678665733332965 0.750291021091423 ISL1/DDIT3/HMGB1 3 GO:0032649 regulation of interferon-gamma production 3/580 112/18722 0.678665733332965 0.750291021091423 ISL1/DDIT3/HMGB1 3 GO:0048662 negative regulation of smooth muscle cell proliferation 2/580 75/18722 0.679852169226107 0.751424058714502 SF1/RHOA 2 GO:0032368 regulation of lipid transport 4/580 149/18722 0.682053489995588 0.753498998092513 LRP1/ITGAV/CAV1/NFKBIA 4 GO:0045834 positive regulation of lipid metabolic process 4/580 149/18722 0.682053489995588 0.753498998092513 ADM/POR/CD81/CDC42 4 GO:0006809 nitric oxide biosynthetic process 2/580 76/18722 0.686875681850142 0.756199796374983 CAV1/DYNLL1 2 GO:0009123 nucleoside monophosphate metabolic process 2/580 76/18722 0.686875681850142 0.756199796374983 DUT/TYMS 2 GO:0032543 mitochondrial translation 2/580 76/18722 0.686875681850142 0.756199796374983 TUFM/IARS2 2 GO:0043536 positive regulation of blood vessel endothelial cell migration 2/580 76/18722 0.686875681850142 0.756199796374983 TMSB4X/HMGB1 2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 2/580 76/18722 0.686875681850142 0.756199796374983 PMAIP1/MIF 2 GO:0071706 tumor necrosis factor superfamily cytokine production 5/580 186/18722 0.687125886294244 0.756199796374983 APP/ISL1/MIF/HMGB1/CYBA 5 GO:1902115 regulation of organelle assembly 5/580 186/18722 0.687125886294244 0.756199796374983 DYNC1H1/HSPA1A/NPM1/TPR/RHOA 5 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 5/580 186/18722 0.687125886294244 0.756199796374983 APP/ISL1/MIF/HMGB1/CYBA 5 GO:0000154 rRNA modification 1/580 37/18722 0.68823774200286 0.756199796374983 FBL 1 GO:0003016 respiratory system process 1/580 37/18722 0.68823774200286 0.756199796374983 GAA 1 GO:0003176 aortic valve development 1/580 37/18722 0.68823774200286 0.756199796374983 ROCK1 1 GO:0007340 acrosome reaction 1/580 37/18722 0.68823774200286 0.756199796374983 SPESP1 1 GO:0030513 positive regulation of BMP signaling pathway 1/580 37/18722 0.68823774200286 0.756199796374983 GPC3 1 GO:0031646 positive regulation of nervous system process 1/580 37/18722 0.68823774200286 0.756199796374983 DAG1 1 GO:0032885 regulation of polysaccharide biosynthetic process 1/580 37/18722 0.68823774200286 0.756199796374983 IGF2 1 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 1/580 37/18722 0.68823774200286 0.756199796374983 GPC1 1 GO:0043368 positive T cell selection 1/580 37/18722 0.68823774200286 0.756199796374983 CTSL 1 GO:0050775 positive regulation of dendrite morphogenesis 1/580 37/18722 0.68823774200286 0.756199796374983 CUX1 1 GO:0051567 histone H3-K9 methylation 1/580 37/18722 0.68823774200286 0.756199796374983 ATRX 1 GO:0051954 positive regulation of amine transport 1/580 37/18722 0.68823774200286 0.756199796374983 ITGB1 1 GO:0071985 multivesicular body sorting pathway 1/580 37/18722 0.68823774200286 0.756199796374983 LEPROT 1 GO:0072529 pyrimidine-containing compound catabolic process 1/580 37/18722 0.68823774200286 0.756199796374983 DUT 1 GO:1900016 negative regulation of cytokine production involved in inflammatory response 1/580 37/18722 0.68823774200286 0.756199796374983 CHID1 1 GO:0008645 hexose transmembrane transport 3/580 114/18722 0.690212816267238 0.758190790850005 SLC2A1/SLC2A8/GPC3 3 GO:0043535 regulation of blood vessel endothelial cell migration 4/580 151/18722 0.692087011167196 0.760070056419983 TMSB4X/RHOA/HMGB1/CSNK2B 4 GO:1901983 regulation of protein acetylation 2/580 77/18722 0.693772219290108 0.76174093293633 SOX4/ISL1 2 GO:0032259 methylation 10/580 364/18722 0.694726818180994 0.762609023214492 FOS/ZC3H13/BTG1/ATRX/KMT2C/BRD4/NSD1/MPHOSPH8/TYMS/FBL 10 GO:0002764 immune response-regulating signaling pathway 13/580 468/18722 0.695241476681127 0.762993890524757 SLC39A10/KCNN4/LGR4/HSPA1A/RTN4/CD81/PUM1/CAV1/NINJ1/NFKBIA/HMGB1/PHPT1/CYBA 13 GO:0000578 embryonic axis specification 1/580 38/18722 0.697915136149948 0.76394523375698 TBX3 1 GO:0008210 estrogen metabolic process 1/580 38/18722 0.697915136149948 0.76394523375698 HSD17B1 1 GO:0035886 vascular associated smooth muscle cell differentiation 1/580 38/18722 0.697915136149948 0.76394523375698 ADM 1 GO:0042491 inner ear auditory receptor cell differentiation 1/580 38/18722 0.697915136149948 0.76394523375698 TRIOBP 1 GO:0046329 negative regulation of JNK cascade 1/580 38/18722 0.697915136149948 0.76394523375698 MARVELD3 1 GO:0046676 negative regulation of insulin secretion 1/580 38/18722 0.697915136149948 0.76394523375698 HMGCR 1 GO:0048246 macrophage chemotaxis 1/580 38/18722 0.697915136149948 0.76394523375698 MIF 1 GO:0048713 regulation of oligodendrocyte differentiation 1/580 38/18722 0.697915136149948 0.76394523375698 DAG1 1 GO:0051930 regulation of sensory perception of pain 1/580 38/18722 0.697915136149948 0.76394523375698 SLC9A1 1 GO:1901186 positive regulation of ERBB signaling pathway 1/580 38/18722 0.697915136149948 0.76394523375698 RTN4 1 GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 1/580 38/18722 0.697915136149948 0.76394523375698 HSPA1A 1 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 2/580 78/18722 0.700542893048027 0.766280572804886 PMAIP1/S100A9 2 GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 2/580 78/18722 0.700542893048027 0.766280572804886 PSAP/GNAI2 2 GO:0061045 negative regulation of wound healing 2/580 78/18722 0.700542893048027 0.766280572804886 GJA1/HMGCR 2 GO:0015749 monosaccharide transmembrane transport 3/580 116/18722 0.70144559621252 0.767087577706191 SLC2A1/SLC2A8/GPC3 3 GO:0009615 response to virus 10/580 367/18722 0.704346996116695 0.770079426172719 TPT1/ENO1/IL10RB/PMAIP1/PUM1/CDK6/EIF2AK4/CFL1/AP1S1/STMN1 10 GO:0019221 cytokine-mediated signaling pathway 13/580 472/18722 0.706592662501967 0.770944001284241 CSF3R/EGR1/P4HB/HSPA1A/IL10RB/PRLR/SPPL2A/CAV1/IL6ST/TMSB4X/KRT8/NFKBIA/CSNK2B 13 GO:0030301 cholesterol transport 3/580 117/18722 0.706944648183275 0.770944001284241 LRP1/CAV1/NFKBIA 3 GO:0072676 lymphocyte migration 3/580 117/18722 0.706944648183275 0.770944001284241 APP/PLEC/RHOA 3 GO:0001895 retina homeostasis 2/580 79/18722 0.707188867648416 0.770944001284241 SLC2A1/ACTG1 2 GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 2/580 79/18722 0.707188867648416 0.770944001284241 GAPDH/S100A9 2 GO:0002701 negative regulation of production of molecular mediator of immune response 1/580 39/18722 0.707292636740455 0.770944001284241 PRKDC 1 GO:0016572 histone phosphorylation 1/580 39/18722 0.707292636740455 0.770944001284241 CDK1 1 GO:0017158 regulation of calcium ion-dependent exocytosis 1/580 39/18722 0.707292636740455 0.770944001284241 GNAI2 1 GO:0021587 cerebellum morphogenesis 1/580 39/18722 0.707292636740455 0.770944001284241 HSPA5 1 GO:0043267 negative regulation of potassium ion transport 1/580 39/18722 0.707292636740455 0.770944001284241 CAV1 1 GO:0045622 regulation of T-helper cell differentiation 1/580 39/18722 0.707292636740455 0.770944001284241 PRKCZ 1 GO:0046326 positive regulation of glucose import 1/580 39/18722 0.707292636740455 0.770944001284241 GPC3 1 GO:0051931 regulation of sensory perception 1/580 39/18722 0.707292636740455 0.770944001284241 SLC9A1 1 GO:0006164 purine nucleotide biosynthetic process 5/580 191/18722 0.709189525625003 0.772830478838305 SLC26A2/ALDOA/ENO1/ACSS1/TMSB4X 5 GO:0051147 regulation of muscle cell differentiation 4/580 155/18722 0.711473226546774 0.775137497462883 YBX1/XBP1/IGF2/MORF4L2 4 GO:0034219 carbohydrate transmembrane transport 3/580 118/18722 0.712365826849443 0.775928210931325 SLC2A1/SLC2A8/GPC3 3 GO:0002714 positive regulation of B cell mediated immunity 1/580 40/18722 0.716379521646013 0.777387110400281 TFRC 1 GO:0002891 positive regulation of immunoglobulin mediated immune response 1/580 40/18722 0.716379521646013 0.777387110400281 TFRC 1 GO:0006730 one-carbon metabolic process 1/580 40/18722 0.716379521646013 0.777387110400281 TYMS 1 GO:0007339 binding of sperm to zona pellucida 1/580 40/18722 0.716379521646013 0.777387110400281 ALDOA 1 GO:0009069 serine family amino acid metabolic process 1/580 40/18722 0.716379521646013 0.777387110400281 GLDC 1 GO:0010543 regulation of platelet activation 1/580 40/18722 0.716379521646013 0.777387110400281 IL6ST 1 GO:0031111 negative regulation of microtubule polymerization or depolymerization 1/580 40/18722 0.716379521646013 0.777387110400281 STMN1 1 GO:0032094 response to food 1/580 40/18722 0.716379521646013 0.777387110400281 PLEC 1 GO:0032892 positive regulation of organic acid transport 1/580 40/18722 0.716379521646013 0.777387110400281 ITGB1 1 GO:0034122 negative regulation of toll-like receptor signaling pathway 1/580 40/18722 0.716379521646013 0.777387110400281 LGR4 1 GO:0045022 early endosome to late endosome transport 1/580 40/18722 0.716379521646013 0.777387110400281 HOOK2 1 GO:0055081 anion homeostasis 1/580 40/18722 0.716379521646013 0.777387110400281 SLC12A9 1 GO:0097352 autophagosome maturation 1/580 40/18722 0.716379521646013 0.777387110400281 CALM1 1 GO:1901661 quinone metabolic process 1/580 40/18722 0.716379521646013 0.777387110400281 HMGCR 1 GO:1901998 toxin transport 1/580 40/18722 0.716379521646013 0.777387110400281 HSPA5 1 GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 1/580 40/18722 0.716379521646013 0.777387110400281 HSPA1A 1 GO:0001523 retinoid metabolic process 2/580 81/18722 0.720111616769086 0.781072558207327 LRP2/LRP1 2 GO:0021954 central nervous system neuron development 2/580 81/18722 0.720111616769086 0.781072558207327 NRP2/MYCBP2 2 GO:0016197 endosomal transport 6/580 230/18722 0.72073789965108 0.781569589945715 TINAGL1/TMEM87A/GCC2/CMTM6/LEPROT/RAB11A 6 GO:0050777 negative regulation of immune response 5/580 194/18722 0.721893665120804 0.782640428083184 GRN/CD46/CD55/GPX1/SERPINB9 5 GO:0006304 DNA modification 3/580 120/18722 0.722975820104073 0.783448401515388 FOS/ATRX/MPHOSPH8 3 GO:0071774 response to fibroblast growth factor 3/580 120/18722 0.722975820104073 0.783448401515388 IER2/GPC1/ZFP36L1 3 GO:0006418 tRNA aminoacylation for protein translation 1/580 41/18722 0.725184782187995 0.784927722121565 IARS2 1 GO:0007099 centriole replication 1/580 41/18722 0.725184782187995 0.784927722121565 NPM1 1 GO:0031062 positive regulation of histone methylation 1/580 41/18722 0.725184782187995 0.784927722121565 BRD4 1 GO:0050691 regulation of defense response to virus by host 1/580 41/18722 0.725184782187995 0.784927722121565 EIF2AK4 1 GO:2000008 regulation of protein localization to cell surface 1/580 41/18722 0.725184782187995 0.784927722121565 LEPROT 1 GO:0018393 internal peptidyl-lysine acetylation 4/580 158/18722 0.725418026963 0.784997497302213 ISL1/POR/NCOA3/MORF4L2 4 GO:0001910 regulation of leukocyte mediated cytotoxicity 2/580 82/18722 0.726390947474545 0.785136950198492 CADM1/SERPINB9 2 GO:0002312 B cell activation involved in immune response 2/580 82/18722 0.726390947474545 0.785136950198492 TFRC/XBP1 2 GO:0007032 endosome organization 2/580 82/18722 0.726390947474545 0.785136950198492 HOOK2/RAB11A 2 GO:0046889 positive regulation of lipid biosynthetic process 2/580 82/18722 0.726390947474545 0.785136950198492 ADM/POR 2 GO:0072527 pyrimidine-containing compound metabolic process 2/580 82/18722 0.726390947474545 0.785136950198492 DUT/TYMS 2 GO:0002455 humoral immune response mediated by circulating immunoglobulin 3/580 121/18722 0.728165340449887 0.78687197918969 CD46/CD81/CD55 3 GO:0022408 negative regulation of cell-cell adhesion 5/580 196/18722 0.73014029216753 0.788822880109449 CDH1/SPINT2/GLI3/DLG5/HMGB1 5 GO:0018205 peptidyl-lysine modification 10/580 376/18722 0.732048515440274 0.789751997409337 EGR1/SOX4/ISL1/ATRX/POR/KMT2C/BRD4/NSD1/NCOA3/MORF4L2 10 GO:0001510 RNA methylation 2/580 83/18722 0.732550683763533 0.789751997409337 ZC3H13/FBL 2 GO:0061053 somite development 2/580 83/18722 0.732550683763533 0.789751997409337 RBBP6/PRKDC 2 GO:0050868 negative regulation of T cell activation 3/580 122/18722 0.733278396032544 0.789751997409337 GLI3/DLG5/HMGB1 3 GO:0007212 dopamine receptor signaling pathway 1/580 42/18722 0.733717131972855 0.789751997409337 NCSTN 1 GO:0007520 myoblast fusion 1/580 42/18722 0.733717131972855 0.789751997409337 CD81 1 GO:0010677 negative regulation of cellular carbohydrate metabolic process 1/580 42/18722 0.733717131972855 0.789751997409337 PGP 1 GO:0010939 regulation of necrotic cell death 1/580 42/18722 0.733717131972855 0.789751997409337 CAV1 1 GO:0014003 oligodendrocyte development 1/580 42/18722 0.733717131972855 0.789751997409337 NCSTN 1 GO:0021575 hindbrain morphogenesis 1/580 42/18722 0.733717131972855 0.789751997409337 HSPA5 1 GO:0021879 forebrain neuron differentiation 1/580 42/18722 0.733717131972855 0.789751997409337 NRP2 1 GO:0032691 negative regulation of interleukin-1 beta production 1/580 42/18722 0.733717131972855 0.789751997409337 SERPINB1 1 GO:0046596 regulation of viral entry into host cell 1/580 42/18722 0.733717131972855 0.789751997409337 P4HB 1 GO:0048489 synaptic vesicle transport 1/580 42/18722 0.733717131972855 0.789751997409337 KIF5B 1 GO:0060999 positive regulation of dendritic spine development 1/580 42/18722 0.733717131972855 0.789751997409337 DLG5 1 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis 1/580 42/18722 0.733717131972855 0.789751997409337 RHOA 1 GO:0006475 internal protein amino acid acetylation 4/580 160/18722 0.734432610427745 0.790339211267802 ISL1/POR/NCOA3/MORF4L2 4 GO:0010876 lipid localization 12/580 448/18722 0.736549001577028 0.792433357930778 LRP1/ITGAV/KCNN4/SLC2A1/PSAP/SLC27A2/LRP10/ATP10D/CROT/CAV1/PLIN2/NFKBIA 12 GO:0050852 T cell receptor signaling pathway 3/580 123/18722 0.738315410948976 0.794080512277924 KCNN4/CD81/PHPT1 3 GO:0009953 dorsal/ventral pattern formation 2/580 84/18722 0.738592194391378 0.794080512277924 GLI3/DDIT3 2 GO:0032508 DNA duplex unwinding 2/580 84/18722 0.738592194391378 0.794080512277924 PURA/ATRX 2 GO:0006909 phagocytosis 8/580 308/18722 0.741899175787783 0.796072043110384 LRP1/ITGAV/ITGB1/MET/LMAN2/HMGB1/CDC42/CYBA 8 GO:0034661 ncRNA catabolic process 1/580 43/18722 0.741985015455496 0.796072043110384 KCNQ1OT1 1 GO:0042088 T-helper 1 type immune response 1/580 43/18722 0.741985015455496 0.796072043110384 HMGB1 1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/580 43/18722 0.741985015455496 0.796072043110384 MIF 1 GO:0045494 photoreceptor cell maintenance 1/580 43/18722 0.741985015455496 0.796072043110384 SLC2A1 1 GO:0090278 negative regulation of peptide hormone secretion 1/580 43/18722 0.741985015455496 0.796072043110384 HMGCR 1 GO:0098927 vesicle-mediated transport between endosomal compartments 1/580 43/18722 0.741985015455496 0.796072043110384 HOOK2 1 GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation 1/580 43/18722 0.741985015455496 0.796072043110384 RHOA 1 GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 1/580 43/18722 0.741985015455496 0.796072043110384 HSPA1A 1 GO:2000779 regulation of double-strand break repair 2/580 85/18722 0.74451687817827 0.798604243636332 PRKDC/FUS 2 GO:0072522 purine-containing compound biosynthetic process 5/580 200/18722 0.746100059616786 0.800117910370688 SLC26A2/ALDOA/ENO1/ACSS1/TMSB4X 5 GO:0006473 protein acetylation 5/580 201/18722 0.749979254078434 0.802798935834505 SOX4/ISL1/POR/NCOA3/MORF4L2 5 GO:0002792 negative regulation of peptide secretion 1/580 44/18722 0.74999661623904 0.802798935834505 HMGCR 1 GO:0006378 mRNA polyadenylation 1/580 44/18722 0.74999661623904 0.802798935834505 APP 1 GO:0007528 neuromuscular junction development 1/580 44/18722 0.74999661623904 0.802798935834505 APP 1 GO:0030521 androgen receptor signaling pathway 1/580 44/18722 0.74999661623904 0.802798935834505 RHOA 1 GO:0032620 interleukin-17 production 1/580 44/18722 0.74999661623904 0.802798935834505 DDIT3 1 GO:0032660 regulation of interleukin-17 production 1/580 44/18722 0.74999661623904 0.802798935834505 DDIT3 1 GO:0043039 tRNA aminoacylation 1/580 44/18722 0.74999661623904 0.802798935834505 IARS2 1 GO:0006493 protein O-linked glycosylation 2/580 86/18722 0.750326160841237 0.802798935834505 C1GALT1/GALNT11 2 GO:0022406 membrane docking 2/580 86/18722 0.750326160841237 0.802798935834505 ROCK1/CALM1 2 GO:0051262 protein tetramerization 2/580 87/18722 0.756021491992958 0.808520562667775 ALDOA/RRM2 2 GO:0003254 regulation of membrane depolarization 1/580 45/18722 0.757759865119078 0.808520562667775 GJA5 1 GO:0006110 regulation of glycolytic process 1/580 45/18722 0.757759865119078 0.808520562667775 APP 1 GO:0010824 regulation of centrosome duplication 1/580 45/18722 0.757759865119078 0.808520562667775 NPM1 1 GO:0035384 thioester biosynthetic process 1/580 45/18722 0.757759865119078 0.808520562667775 ACSS1 1 GO:0042551 neuron maturation 1/580 45/18722 0.757759865119078 0.808520562667775 APP 1 GO:0043038 amino acid activation 1/580 45/18722 0.757759865119078 0.808520562667775 IARS2 1 GO:0043631 RNA polyadenylation 1/580 45/18722 0.757759865119078 0.808520562667775 APP 1 GO:0044088 regulation of vacuole organization 1/580 45/18722 0.757759865119078 0.808520562667775 GRN 1 GO:0071354 cellular response to interleukin-6 1/580 45/18722 0.757759865119078 0.808520562667775 IL6ST 1 GO:0071616 acyl-CoA biosynthetic process 1/580 45/18722 0.757759865119078 0.808520562667775 ACSS1 1 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process 1/580 45/18722 0.757759865119078 0.808520562667775 HSPA1A 1 GO:0030101 natural killer cell activation 2/580 88/18722 0.761604342300129 0.812249895904128 PBX1/HECTD1 2 GO:1901657 glycosyl compound metabolic process 2/580 88/18722 0.761604342300129 0.812249895904128 GUSB/FUCA1 2 GO:0006383 transcription by RNA polymerase III 1/580 46/18722 0.765282447880279 0.814491685375555 BDP1 1 GO:0007019 microtubule depolymerization 1/580 46/18722 0.765282447880279 0.814491685375555 STMN1 1 GO:0010828 positive regulation of glucose transmembrane transport 1/580 46/18722 0.765282447880279 0.814491685375555 GPC3 1 GO:0010830 regulation of myotube differentiation 1/580 46/18722 0.765282447880279 0.814491685375555 XBP1 1 GO:0031057 negative regulation of histone modification 1/580 46/18722 0.765282447880279 0.814491685375555 KDM5A 1 GO:0044818 mitotic G2/M transition checkpoint 1/580 46/18722 0.765282447880279 0.814491685375555 CDK1 1 GO:0046839 phospholipid dephosphorylation 1/580 46/18722 0.765282447880279 0.814491685375555 PLPP3 1 GO:0061028 establishment of endothelial barrier 1/580 46/18722 0.765282447880279 0.814491685375555 ROCK1 1 GO:2000107 negative regulation of leukocyte apoptotic process 1/580 46/18722 0.765282447880279 0.814491685375555 SLC39A10 1 GO:0016482 cytosolic transport 4/580 168/18722 0.7682647825256 0.817478724211065 TMEM87A/GCC2/KIF5B/HOOK2 4 GO:0007098 centrosome cycle 3/580 130/18722 0.771486117695545 0.819437058512891 NPM1/CDK1/RANBP1 3 GO:0015918 sterol transport 3/580 130/18722 0.771486117695545 0.819437058512891 LRP1/CAV1/NFKBIA 3 GO:0030534 adult behavior 3/580 130/18722 0.771486117695545 0.819437058512891 APP/NCSTN/PUM1 3 GO:0035278 miRNA mediated inhibition of translation 2/580 90/18722 0.772438572329256 0.819437058512891 TNRC6A/EIF4G1 2 GO:0040033 negative regulation of translation, ncRNA-mediated 2/580 90/18722 0.772438572329256 0.819437058512891 TNRC6A/EIF4G1 2 GO:0010712 regulation of collagen metabolic process 1/580 47/18722 0.772571812852941 0.819437058512891 ITGB1 1 GO:0016574 histone ubiquitination 1/580 47/18722 0.772571812852941 0.819437058512891 DDB1 1 GO:0032008 positive regulation of TOR signaling 1/580 47/18722 0.772571812852941 0.819437058512891 SLC38A9 1 GO:0032369 negative regulation of lipid transport 1/580 47/18722 0.772571812852941 0.819437058512891 ITGAV 1 GO:0035315 hair cell differentiation 1/580 47/18722 0.772571812852941 0.819437058512891 TRIOBP 1 GO:0035850 epithelial cell differentiation involved in kidney development 1/580 47/18722 0.772571812852941 0.819437058512891 IQGAP1 1 GO:0051489 regulation of filopodium assembly 1/580 47/18722 0.772571812852941 0.819437058512891 CDC42 1 GO:0061001 regulation of dendritic spine morphogenesis 1/580 47/18722 0.772571812852941 0.819437058512891 CFL1 1 GO:0090279 regulation of calcium ion import 1/580 47/18722 0.772571812852941 0.819437058512891 VDAC1 1 GO:0006354 DNA-templated transcription, elongation 2/580 91/18722 0.77769297517618 0.824304928793166 SERTAD1/BRD4 2 GO:0042147 retrograde transport, endosome to Golgi 2/580 91/18722 0.77769297517618 0.824304928793166 TMEM87A/GCC2 2 GO:0045974 regulation of translation, ncRNA-mediated 2/580 91/18722 0.77769297517618 0.824304928793166 TNRC6A/EIF4G1 2 GO:0002673 regulation of acute inflammatory response 1/580 48/18722 0.779635178236892 0.825235142007234 IL6ST 1 GO:0010569 regulation of double-strand break repair via homologous recombination 1/580 48/18722 0.779635178236892 0.825235142007234 FUS 1 GO:0030261 chromosome condensation 1/580 48/18722 0.779635178236892 0.825235142007234 CDK1 1 GO:0044458 motile cilium assembly 1/580 48/18722 0.779635178236892 0.825235142007234 E2F4 1 GO:0045912 negative regulation of carbohydrate metabolic process 1/580 48/18722 0.779635178236892 0.825235142007234 PGP 1 GO:0061647 histone H3-K9 modification 1/580 48/18722 0.779635178236892 0.825235142007234 ATRX 1 GO:0048525 negative regulation of viral process 2/580 92/18722 0.782840938754322 0.828251411771235 PPIA/MPHOSPH8 2 GO:1903351 cellular response to dopamine 2/580 92/18722 0.782840938754322 0.828251411771235 NCSTN/ID1 2 GO:0034470 ncRNA processing 10/580 395/18722 0.784704354987934 0.829459486806935 RPS21/RPS6/RPL7/RPS16/RPL14/RPS25/RPS17/PRKDC/HNRNPA2B1/FBL 10 GO:0001913 T cell mediated cytotoxicity 1/580 49/18722 0.786479539199867 0.829459486806935 CTSC 1 GO:0002204 somatic recombination of immunoglobulin genes involved in immune response 1/580 49/18722 0.786479539199867 0.829459486806935 TFRC 1 GO:0002208 somatic diversification of immunoglobulins involved in immune response 1/580 49/18722 0.786479539199867 0.829459486806935 TFRC 1 GO:0007602 phototransduction 1/580 49/18722 0.786479539199867 0.829459486806935 GNAQ 1 GO:0008206 bile acid metabolic process 1/580 49/18722 0.786479539199867 0.829459486806935 SLC27A2 1 GO:0009994 oocyte differentiation 1/580 49/18722 0.786479539199867 0.829459486806935 LGR5 1 GO:0032692 negative regulation of interleukin-1 production 1/580 49/18722 0.786479539199867 0.829459486806935 SERPINB1 1 GO:0042304 regulation of fatty acid biosynthetic process 1/580 49/18722 0.786479539199867 0.829459486806935 ACADVL 1 GO:0045190 isotype switching 1/580 49/18722 0.786479539199867 0.829459486806935 TFRC 1 GO:0046605 regulation of centrosome cycle 1/580 49/18722 0.786479539199867 0.829459486806935 NPM1 1 GO:0070741 response to interleukin-6 1/580 49/18722 0.786479539199867 0.829459486806935 IL6ST 1 GO:1901799 negative regulation of proteasomal protein catabolic process 1/580 49/18722 0.786479539199867 0.829459486806935 EIF3H 1 GO:1990573 potassium ion import across plasma membrane 1/580 49/18722 0.786479539199867 0.829459486806935 SLC12A9 1 GO:0019217 regulation of fatty acid metabolic process 2/580 93/18722 0.787884001487336 0.830564027859837 CAV1/ACADVL 2 GO:1903350 response to dopamine 2/580 93/18722 0.787884001487336 0.830564027859837 NCSTN/ID1 2 GO:0002690 positive regulation of leukocyte chemotaxis 2/580 94/18722 0.792823708781952 0.83401387453684 LGMN/HMGB1 2 GO:1903035 negative regulation of response to wounding 2/580 94/18722 0.792823708781952 0.83401387453684 GJA1/HMGCR 2 GO:0000387 spliceosomal snRNP assembly 1/580 50/18722 0.793111674757307 0.83401387453684 SNRPD2 1 GO:0001961 positive regulation of cytokine-mediated signaling pathway 1/580 50/18722 0.793111674757307 0.83401387453684 HSPA1A 1 GO:0002448 mast cell mediated immunity 1/580 50/18722 0.793111674757307 0.83401387453684 SERPINB9 1 GO:0007080 mitotic metaphase plate congression 1/580 50/18722 0.793111674757307 0.83401387453684 RAB11A 1 GO:0007140 male meiotic nuclear division 1/580 50/18722 0.793111674757307 0.83401387453684 SLC2A8 1 GO:0008089 anterograde axonal transport 1/580 50/18722 0.793111674757307 0.83401387453684 KIF5B 1 GO:0051646 mitochondrion localization 1/580 50/18722 0.793111674757307 0.83401387453684 ARMCX3 1 GO:1902930 regulation of alcohol biosynthetic process 1/580 50/18722 0.793111674757307 0.83401387453684 POR 1 GO:0001505 regulation of neurotransmitter levels 5/580 213/18722 0.793129083439356 0.83401387453684 ITGB1/SLC38A1/CALM1/SLC6A4/VAMP2 5 GO:0050728 negative regulation of inflammatory response 4/580 176/18722 0.798632629725296 0.839611293140224 GRN/SERPINF1/ISL1/GPX1 4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone 1/580 51/18722 0.799538154440296 0.839803964837809 NDUFB9 1 GO:0009584 detection of visible light 1/580 51/18722 0.799538154440296 0.839803964837809 GNAQ 1 GO:0032964 collagen biosynthetic process 1/580 51/18722 0.799538154440296 0.839803964837809 SERPINH1 1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 1/580 51/18722 0.799538154440296 0.839803964837809 RHOA 1 GO:0015914 phospholipid transport 2/580 96/18722 0.802399262277785 0.842238539574357 KCNN4/ATP10D 2 GO:0042472 inner ear morphogenesis 2/580 96/18722 0.802399262277785 0.842238539574357 TRIOBP/TFAP2A 2 GO:0043648 dicarboxylic acid metabolic process 2/580 96/18722 0.802399262277785 0.842238539574357 FOLR1/SLC19A1 2 GO:0035176 social behavior 1/580 52/18722 0.805765344758149 0.845527774803758 SLC6A4 1 GO:0002443 leukocyte mediated immunity 11/580 440/18722 0.805896500904119 0.845527774803758 CD46/CADM1/CTSC/KIF5B/TFRC/CD81/VAMP2/CD55/PRKCZ/SERPINB9/HMGB1 11 GO:1990868 response to chemokine 2/580 97/18722 0.80703821761043 0.846343799347488 DUSP1/RHOA 2 GO:1990869 cellular response to chemokine 2/580 97/18722 0.80703821761043 0.846343799347488 DUSP1/RHOA 2 GO:0016925 protein sumoylation 1/580 53/18722 0.811799415461966 0.850186687978745 EGR1 1 GO:0032784 regulation of DNA-templated transcription, elongation 1/580 53/18722 0.811799415461966 0.850186687978745 BRD4 1 GO:0033059 cellular pigmentation 1/580 53/18722 0.811799415461966 0.850186687978745 RAB11A 1 GO:0043113 receptor clustering 1/580 53/18722 0.811799415461966 0.850186687978745 CD81 1 GO:0050819 negative regulation of coagulation 1/580 53/18722 0.811799415461966 0.850186687978745 ANXA5 1 GO:0097479 synaptic vesicle localization 1/580 53/18722 0.811799415461966 0.850186687978745 KIF5B 1 GO:0002444 myeloid leukocyte mediated immunity 2/580 99/18722 0.816026260810853 0.85431010393587 VAMP2/SERPINB9 2 GO:0042113 B cell activation 8/580 334/18722 0.816104018874881 0.85431010393587 SLC39A10/ITGB1/ZFP36L1/PRKDC/TFRC/CD81/MIF/XBP1 8 GO:1903038 negative regulation of leukocyte cell-cell adhesion 3/580 141/18722 0.81659203247263 0.8546286100428 GLI3/DLG5/HMGB1 3 GO:0035065 regulation of histone acetylation 1/580 54/18722 0.817646345615272 0.854962489536113 ISL1 1 GO:0051703 biological process involved in intraspecies interaction between organisms 1/580 54/18722 0.817646345615272 0.854962489536113 SLC6A4 1 GO:0070228 regulation of lymphocyte apoptotic process 1/580 54/18722 0.817646345615272 0.854962489536113 SLC39A10 1 GO:2000300 regulation of synaptic vesicle exocytosis 1/580 54/18722 0.817646345615272 0.854962489536113 CALM1 1 GO:0006641 triglyceride metabolic process 2/580 100/18722 0.82037845357416 0.857241111564462 CAV1/GPX1 2 GO:0051588 regulation of neurotransmitter transport 2/580 100/18722 0.82037845357416 0.857241111564462 ITGB1/CALM1 2 GO:0060079 excitatory postsynaptic potential 2/580 100/18722 0.82037845357416 0.857241111564462 APP/PRKCZ 2 GO:0000768 syncytium formation by plasma membrane fusion 1/580 55/18722 0.823311929477664 0.858955537012251 CD81 1 GO:0002067 glandular epithelial cell differentiation 1/580 55/18722 0.823311929477664 0.858955537012251 CDK6 1 GO:0006360 transcription by RNA polymerase I 1/580 55/18722 0.823311929477664 0.858955537012251 NCL 1 GO:0042220 response to cocaine 1/580 55/18722 0.823311929477664 0.858955537012251 HSPA5 1 GO:0046164 alcohol catabolic process 1/580 55/18722 0.823311929477664 0.858955537012251 TPI1 1 GO:0061098 positive regulation of protein tyrosine kinase activity 1/580 55/18722 0.823311929477664 0.858955537012251 ERBB3 1 GO:0140253 cell-cell fusion 1/580 55/18722 0.823311929477664 0.858955537012251 CD81 1 GO:0070555 response to interleukin-1 3/580 143/18722 0.823928344389123 0.859405860003097 EGR1/APP/CYBA 3 GO:0034660 ncRNA metabolic process 12/580 485/18722 0.824521225340976 0.859831439251319 RPS21/RPS6/KCNQ1OT1/RPL7/RPS16/RPL14/RPS25/RPS17/PRKDC/IARS2/HNRNPA2B1/FBL 12 GO:0001912 positive regulation of leukocyte mediated cytotoxicity 1/580 56/18722 0.828801782207238 0.862560071220289 CADM1 1 GO:0002090 regulation of receptor internalization 1/580 56/18722 0.828801782207238 0.862560071220289 LRPAP1 1 GO:0045071 negative regulation of viral genome replication 1/580 56/18722 0.828801782207238 0.862560071220289 MPHOSPH8 1 GO:0045599 negative regulation of fat cell differentiation 1/580 56/18722 0.828801782207238 0.862560071220289 DDIT3 1 GO:0070534 protein K63-linked ubiquitination 1/580 56/18722 0.828801782207238 0.862560071220289 HECTD1 1 GO:0098781 ncRNA transcription 1/580 56/18722 0.828801782207238 0.862560071220289 NCL 1 GO:0045833 negative regulation of lipid metabolic process 2/580 102/18722 0.828806914272946 0.862560071220289 ORMDL1/ACADVL 2 GO:0062014 negative regulation of small molecule metabolic process 2/580 102/18722 0.828806914272946 0.862560071220289 ACADVL/PGP 2 GO:1990542 mitochondrial transmembrane transport 2/580 102/18722 0.828806914272946 0.862560071220289 SLC25A36/VDAC1 2 GO:0019233 sensory perception of pain 2/580 103/18722 0.832886258431545 0.866611630417251 SLC9A1/NR2F6 2 GO:0006949 syncytium formation 1/580 57/18722 0.834121345387341 0.866733328283406 CD81 1 GO:0010257 NADH dehydrogenase complex assembly 1/580 57/18722 0.834121345387341 0.866733328283406 NDUFB9 1 GO:0032981 mitochondrial respiratory chain complex I assembly 1/580 57/18722 0.834121345387341 0.866733328283406 NDUFB9 1 GO:0051155 positive regulation of striated muscle cell differentiation 1/580 57/18722 0.834121345387341 0.866733328283406 MORF4L2 1 GO:0051289 protein homotetramerization 1/580 57/18722 0.834121345387341 0.866733328283406 ALDOA 1 GO:0060760 positive regulation of response to cytokine stimulus 1/580 57/18722 0.834121345387341 0.866733328283406 HSPA1A 1 GO:0002695 negative regulation of leukocyte activation 4/580 187/18722 0.835054382287699 0.867509031052064 GRN/GLI3/DLG5/HMGB1 4 GO:0022600 digestive system process 2/580 104/18722 0.836877717262037 0.86920908061316 KCNN4/COPA 2 GO:0006310 DNA recombination 7/580 305/18722 0.837492176977985 0.869653073258452 PRKDC/TFRC/NIPBL/FUS/HMGB1/HMGB3/HMGB2 7 GO:0016079 synaptic vesicle exocytosis 2/580 105/18722 0.84078280931692 0.872875188868972 CALM1/VAMP2 2 GO:0043551 regulation of phosphatidylinositol 3-kinase activity 1/580 59/18722 0.844270533532763 0.875863713645 CDC42 1 GO:0046324 regulation of glucose import 1/580 59/18722 0.844270533532763 0.875863713645 GPC3 1 GO:0051568 histone H3-K4 methylation 1/580 59/18722 0.844270533532763 0.875863713645 KMT2C 1 GO:0006906 vesicle fusion 2/580 106/18722 0.844603043581558 0.875863713645 KIF5B/VAMP2 2 GO:0099565 chemical synaptic transmission, postsynaptic 2/580 106/18722 0.844603043581558 0.875863713645 APP/PRKCZ 2 GO:0001959 regulation of cytokine-mediated signaling pathway 3/580 150/18722 0.847661396984891 0.878839312834759 HSPA1A/SPPL2A/CAV1 3 GO:0000018 regulation of DNA recombination 2/580 107/18722 0.848339918609975 0.879346770995096 TFRC/FUS 2 GO:0006081 cellular aldehyde metabolic process 1/580 60/18722 0.849110221179498 0.879753093942046 TPI1 1 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 1/580 60/18722 0.849110221179498 0.879753093942046 CDK1 1 GO:0002832 negative regulation of response to biotic stimulus 2/580 108/18722 0.851994921723193 0.88215235550636 GRN/SERPINB9 2 GO:0006958 complement activation, classical pathway 2/580 108/18722 0.851994921723193 0.88215235550636 CD46/CD55 2 GO:0140053 mitochondrial gene expression 2/580 108/18722 0.851994921723193 0.88215235550636 TUFM/IARS2 2 GO:0019932 second-messenger-mediated signaling 7/580 312/18722 0.853635863366805 0.882957400985988 EGFR/NFAT5/SLC9A1/ADM/CALM1/GSTO1/CALM2 7 GO:0006900 vesicle budding from membrane 1/580 61/18722 0.853799754547619 0.882957400985988 TMED9 1 GO:0043954 cellular component maintenance 1/580 61/18722 0.853799754547619 0.882957400985988 IGF1R 1 GO:0060998 regulation of dendritic spine development 1/580 61/18722 0.853799754547619 0.882957400985988 DLG5 1 GO:0008643 carbohydrate transport 3/580 152/18722 0.853911500674043 0.882957400985988 SLC2A1/SLC2A8/GPC3 3 GO:0016573 histone acetylation 3/580 152/18722 0.853911500674043 0.882957400985988 ISL1/NCOA3/MORF4L2 3 GO:0019933 cAMP-mediated signaling 1/580 62/18722 0.858343784468973 0.886751875070012 ADM 1 GO:0032623 interleukin-2 production 1/580 62/18722 0.858343784468973 0.886751875070012 SPTBN1 1 GO:0032663 regulation of interleukin-2 production 1/580 62/18722 0.858343784468973 0.886751875070012 SPTBN1 1 GO:1902750 negative regulation of cell cycle G2/M phase transition 1/580 62/18722 0.858343784468973 0.886751875070012 CDK1 1 GO:0090174 organelle membrane fusion 2/580 110/18722 0.859065200926658 0.887300077617119 KIF5B/VAMP2 2 GO:0000209 protein polyubiquitination 5/580 236/18722 0.859319528181228 0.887365702835455 NHLRC3/HECTD1/PPIA/ANAPC11/UBE2L3 5 GO:0001756 somitogenesis 1/580 63/18722 0.862746817963507 0.890311837219496 PRKDC 1 GO:0016239 positive regulation of macroautophagy 1/580 63/18722 0.862746817963507 0.890311837219496 VDAC1 1 GO:0031343 positive regulation of cell killing 1/580 63/18722 0.862746817963507 0.890311837219496 CADM1 1 GO:0007281 germ cell development 6/580 278/18722 0.864630832186156 0.892058119010162 LGR5/RPS6/JAM3/ASPM/DYNLL1/HMGB2 6 GO:0000956 nuclear-transcribed mRNA catabolic process 2/580 112/18722 0.865825528290242 0.893092599706789 ZFP36L1/TNRC6A 2 GO:0046854 phosphatidylinositol phosphate biosynthetic process 1/580 64/18722 0.86701322267872 0.893586098321668 TMEM150A 1 GO:0048247 lymphocyte chemotaxis 1/580 64/18722 0.86701322267872 0.893586098321668 PLEC 1 GO:0070542 response to fatty acid 1/580 64/18722 0.86701322267872 0.893586098321668 GLDC 1 GO:0001818 negative regulation of cytokine production 8/580 357/18722 0.867072470807501 0.893586098321668 ATP2B1/LGR4/DDIT3/TMSB4X/CHID1/HMGB1/SERPINB1/ANXA4 8 GO:0051250 negative regulation of lymphocyte activation 3/580 157/18722 0.868566273575669 0.894927279220301 GLI3/DLG5/HMGB1 3 GO:0044344 cellular response to fibroblast growth factor stimulus 2/580 113/18722 0.869093039627912 0.895271700400757 GPC1/ZFP36L1 2 GO:0070936 protein K48-linked ubiquitination 1/580 65/18722 0.871147231192298 0.897189054976833 PPIA 1 GO:0030193 regulation of blood coagulation 1/580 66/18722 0.875152945182139 0.900888905800789 CAV1 1 GO:2000272 negative regulation of signaling receptor activity 1/580 66/18722 0.875152945182139 0.900888905800789 LRPAP1 1 GO:0043279 response to alkaloid 2/580 115/18722 0.875409788288899 0.900888905800789 FOSB/HSPA5 2 GO:0043543 protein acylation 5/580 243/18722 0.875569587840506 0.900888905800789 SOX4/ISL1/POR/NCOA3/MORF4L2 5 GO:0017157 regulation of exocytosis 4/580 202/18722 0.875708179558238 0.900888905800789 ATP6AP1/CALM1/VAMP2/GNAI2 4 GO:0006513 protein monoubiquitination 1/580 67/18722 0.879034339467857 0.903511317760222 DDB1 1 GO:0009583 detection of light stimulus 1/580 67/18722 0.879034339467857 0.903511317760222 GNAQ 1 GO:0042130 negative regulation of T cell proliferation 1/580 67/18722 0.879034339467857 0.903511317760222 DLG5 1 GO:0043967 histone H4 acetylation 1/580 67/18722 0.879034339467857 0.903511317760222 MORF4L2 1 GO:0060759 regulation of response to cytokine stimulus 3/580 162/18722 0.881909777939972 0.906266543791164 HSPA1A/SPPL2A/CAV1 3 GO:0009247 glycolipid biosynthetic process 1/580 68/18722 0.882795265927715 0.906575575586179 GPAA1 1 GO:1900046 regulation of hemostasis 1/580 68/18722 0.882795265927715 0.906575575586179 CAV1 1 GO:1901607 alpha-amino acid biosynthetic process 1/580 68/18722 0.882795265927715 0.906575575586179 ILVBL 1 GO:0050688 regulation of defense response to virus 1/580 69/18722 0.886439457294817 0.909715338896336 EIF2AK4 1 GO:0051966 regulation of synaptic transmission, glutamatergic 1/580 69/18722 0.886439457294817 0.909715338896336 EGFR 1 GO:0070192 chromosome organization involved in meiotic cell cycle 1/580 69/18722 0.886439457294817 0.909715338896336 ATRX 1 GO:0016064 immunoglobulin mediated immune response 4/580 207/18722 0.88718923763275 0.910283949752905 CD46/TFRC/CD81/CD55 4 GO:0007286 spermatid development 3/580 165/18722 0.889325092473751 0.912274151983991 JAM3/DYNLL1/HMGB2 3 GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response 1/580 70/18722 0.889970530836286 0.912734936917214 TFRC 1 GO:0006302 double-strand break repair 5/580 251/18722 0.892163772995411 0.914782563536521 PRKDC/NIPBL/FUS/HMGB1/HMGB2 5 GO:0019724 B cell mediated immunity 4/580 210/18722 0.893624963932611 0.915876973832211 CD46/TFRC/CD81/CD55 4 GO:0050866 negative regulation of cell activation 4/580 210/18722 0.893624963932611 0.915876973832211 GRN/GLI3/DLG5/HMGB1 4 GO:0009451 RNA modification 3/580 167/18722 0.89403463567041 0.916094974774857 ZC3H13/RBM47/FBL 3 GO:0019730 antimicrobial humoral response 2/580 122/18722 0.895369187461009 0.917260372440783 GAPDH/S100A9 2 GO:0008654 phospholipid biosynthetic process 5/580 253/18722 0.896002144669652 0.917706667002544 GPAA1/SERINC1/ISYNA1/TMEM150A/PISD 5 GO:0032729 positive regulation of interferon-gamma production 1/580 72/18722 0.896707237465466 0.918226631759551 ISL1 1 GO:0002253 activation of immune response 8/580 375/18722 0.898413243044369 0.91977107492832 SLC39A10/KCNN4/CD46/PRKDC/CD81/CD55/HMGB1/PHPT1 8 GO:0043547 positive regulation of GTPase activity 5/580 255/18722 0.899721929417736 0.920098015018303 ITGA6/ITGB1/ADRB1/RASA1/RGS10 5 GO:0009166 nucleotide catabolic process 1/580 73/18722 0.899919559303001 0.920098015018303 DUT 1 GO:0042058 regulation of epidermal growth factor receptor signaling pathway 1/580 73/18722 0.899919559303001 0.920098015018303 EGFR 1 GO:0043299 leukocyte degranulation 1/580 73/18722 0.899919559303001 0.920098015018303 VAMP2 1 GO:0051298 centrosome duplication 1/580 73/18722 0.899919559303001 0.920098015018303 NPM1 1 GO:0051865 protein autoubiquitination 1/580 73/18722 0.899919559303001 0.920098015018303 HECTD1 1 GO:1901568 fatty acid derivative metabolic process 1/580 74/18722 0.90303214740983 0.92307747639629 HPGD 1 GO:0007601 visual perception 4/580 215/18722 0.903637403352922 0.923493202152151 EFEMP1/CRYBG3/TACSTD2/TIMP3 4 GO:0048515 spermatid differentiation 3/580 172/18722 0.905031059709471 0.92456652412786 JAM3/DYNLL1/HMGB2 3 GO:0031348 negative regulation of defense response 5/580 258/18722 0.905085225619038 0.92456652412786 GRN/SERPINF1/ISL1/GPX1/SERPINB9 5 GO:0031929 TOR signaling 2/580 126/18722 0.905397435683825 0.924682361301158 RPS6/SLC38A9 2 GO:0016050 vesicle organization 6/580 300/18722 0.906387212425849 0.925489994509906 TMED9/KIF5B/HOOK2/VAMP2/CAV1/RAB11A 6 GO:0008652 cellular amino acid biosynthetic process 1/580 76/18722 0.908970391877106 0.927923900926343 ILVBL 1 GO:0006639 acylglycerol metabolic process 2/580 128/18722 0.910068077347885 0.928783082465036 CAV1/GPX1 2 GO:0006644 phospholipid metabolic process 8/580 383/18722 0.910211414722777 0.928783082465036 GPAA1/PLPP3/SERINC1/ISYNA1/TMEM150A/PISD/HADHA/PGP 8 GO:0050953 sensory perception of light stimulus 4/580 219/18722 0.911038557147557 0.929386555878099 EFEMP1/CRYBG3/TACSTD2/TIMP3 4 GO:0006367 transcription initiation from RNA polymerase II promoter 1/580 77/18722 0.911801946779567 0.929386555878099 HMGB1 1 GO:0010827 regulation of glucose transmembrane transport 1/580 77/18722 0.911801946779567 0.929386555878099 GPC3 1 GO:0032418 lysosome localization 1/580 77/18722 0.911801946779567 0.929386555878099 KIF5B 1 GO:0140056 organelle localization by membrane tethering 1/580 77/18722 0.911801946779567 0.929386555878099 CALM1 1 GO:0006638 neutral lipid metabolic process 2/580 129/18722 0.912321629771711 0.929712510970251 CAV1/GPX1 2 GO:0006956 complement activation 2/580 130/18722 0.914522184647901 0.931366641130275 CD46/CD55 2 GO:0090049 regulation of cell migration involved in sprouting angiogenesis 1/580 78/18722 0.914545570854002 0.931366641130275 RHOA 1 GO:1901616 organic hydroxy compound catabolic process 1/580 78/18722 0.914545570854002 0.931366641130275 TPI1 1 GO:0006650 glycerophospholipid metabolic process 6/580 306/18722 0.915645595886978 0.932282764113471 GPAA1/SERINC1/TMEM150A/PISD/HADHA/PGP 6 GO:0006661 phosphatidylinositol biosynthetic process 2/580 131/18722 0.916670855502482 0.932918194516859 GPAA1/TMEM150A 2 GO:0050853 B cell receptor signaling pathway 2/580 131/18722 0.916670855502482 0.932918194516859 SLC39A10/CD81 2 GO:0002440 production of molecular mediator of immune response 6/580 308/18722 0.918549802446496 0.934625931126373 PRKDC/TFRC/CD81/XBP1/CD55/PRKCZ 6 GO:0046486 glycerolipid metabolic process 8/580 392/18722 0.922071814163758 0.936982148667849 GPAA1/SERINC1/TMEM150A/CAV1/PISD/GPX1/HADHA/PGP 8 GO:0000422 autophagy of mitochondrion 1/580 81/18722 0.922275699118773 0.936982148667849 VDAC1 1 GO:0001960 negative regulation of cytokine-mediated signaling pathway 1/580 81/18722 0.922275699118773 0.936982148667849 CAV1 1 GO:0051149 positive regulation of muscle cell differentiation 1/580 81/18722 0.922275699118773 0.936982148667849 MORF4L2 1 GO:0061726 mitochondrion disassembly 1/580 81/18722 0.922275699118773 0.936982148667849 VDAC1 1 GO:2000106 regulation of leukocyte apoptotic process 1/580 81/18722 0.922275699118773 0.936982148667849 SLC39A10 1 GO:2000243 positive regulation of reproductive process 1/580 81/18722 0.922275699118773 0.936982148667849 CITED2 1 GO:0008543 fibroblast growth factor receptor signaling pathway 1/580 82/18722 0.924694029385986 0.938899269406029 GPC1 1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic 1/580 82/18722 0.924694029385986 0.938899269406029 RPS21 1 GO:0009581 detection of external stimulus 2/580 135/18722 0.924768340818967 0.938899269406029 GNAQ/NR2F6 2 GO:0099024 plasma membrane invagination 2/580 136/18722 0.926673666857914 0.940381724647648 RHOA/CDC42 2 GO:1903305 regulation of regulated secretory pathway 2/580 136/18722 0.926673666857914 0.940381724647648 CALM1/GNAI2 2 GO:0050672 negative regulation of lymphocyte proliferation 1/580 83/18722 0.927037240917967 0.940381724647648 DLG5 1 GO:1901292 nucleoside phosphate catabolic process 1/580 83/18722 0.927037240917967 0.940381724647648 DUT 1 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 7/580 356/18722 0.927635182703622 0.940783086514292 CD46/CTSC/TFRC/CD81/CD55/PRKCZ/HMGB1 7 GO:0007586 digestion 2/580 137/18722 0.928533414393125 0.941488753072253 KCNN4/COPA 2 GO:0015844 monoamine transport 1/580 84/18722 0.929307663165275 0.941657939298844 SLC6A4 1 GO:0032945 negative regulation of mononuclear cell proliferation 1/580 84/18722 0.929307663165275 0.941657939298844 DLG5 1 GO:0098586 cellular response to virus 1/580 84/18722 0.929307663165275 0.941657939298844 PUM1 1 GO:0000724 double-strand break repair via homologous recombination 2/580 138/18722 0.930348572458499 0.942302092879895 NIPBL/FUS 2 GO:0009582 detection of abiotic stimulus 2/580 138/18722 0.930348572458499 0.942302092879895 GNAQ/NR2F6 2 GO:0045921 positive regulation of exocytosis 1/580 86/18722 0.933639099258287 0.945017508302566 ATP6AP1 1 GO:0046928 regulation of neurotransmitter secretion 1/580 86/18722 0.933639099258287 0.945017508302566 CALM1 1 GO:0060761 negative regulation of response to cytokine stimulus 1/580 86/18722 0.933639099258287 0.945017508302566 CAV1 1 GO:0000725 recombinational repair 2/580 140/18722 0.933848989420455 0.945024292818654 NIPBL/FUS 2 GO:0016241 regulation of macroautophagy 2/580 141/18722 0.935536139880136 0.94649005191164 GAPDH/VDAC1 2 GO:1901606 alpha-amino acid catabolic process 1/580 87/18722 0.935704420273 0.94649005191164 GLDC 1 GO:0050829 defense response to Gram-negative bacterium 1/580 88/18722 0.937705570594527 0.948308025404467 HMGB2 1 GO:0010324 membrane invagination 2/580 144/18722 0.940356351662691 0.950782041648517 RHOA/CDC42 2 GO:0070664 negative regulation of leukocyte proliferation 1/580 90/18722 0.941523259451697 0.951594089093598 DLG5 1 GO:0007269 neurotransmitter secretion 2/580 145/18722 0.941885631492871 0.951594089093598 CALM1/VAMP2 2 GO:0099643 signal release from synapse 2/580 145/18722 0.941885631492871 0.951594089093598 CALM1/VAMP2 2 GO:0015850 organic hydroxy compound transport 5/580 284/18722 0.941979661040703 0.951594089093598 LRP1/SLC6A4/MFSD10/CAV1/NFKBIA 5 GO:0050851 antigen receptor-mediated signaling pathway 4/580 240/18722 0.942182494146639 0.951594089093598 SLC39A10/KCNN4/CD81/PHPT1 4 GO:0019935 cyclic-nucleotide-mediated signaling 1/580 91/18722 0.943343595943647 0.952559935895332 ADM 1 GO:0006497 protein lipidation 1/580 92/18722 0.945107361407266 0.95371975220334 GPAA1 1 GO:0035249 synaptic transmission, glutamatergic 1/580 92/18722 0.945107361407266 0.95371975220334 EGFR 1 GO:0070509 calcium ion import 1/580 92/18722 0.945107361407266 0.95371975220334 VDAC1 1 GO:0006637 acyl-CoA metabolic process 1/580 96/18722 0.951631010163538 0.959678193467176 ACSS1 1 GO:0035383 thioester metabolic process 1/580 96/18722 0.951631010163538 0.959678193467176 ACSS1 1 GO:0042158 lipoprotein biosynthetic process 1/580 96/18722 0.951631010163538 0.959678193467176 GPAA1 1 GO:1903046 meiotic cell cycle process 3/580 202/18722 0.951904172827308 0.959745568571387 SLC2A8/ATRX/ASPM 3 GO:0050830 defense response to Gram-positive bacterium 1/580 101/18722 0.958707964283837 0.966395912848749 HMGB2 1 GO:0046488 phosphatidylinositol metabolic process 2/580 159/18722 0.959739746714088 0.967226340621284 GPAA1/TMEM150A 2 GO:0034308 primary alcohol metabolic process 1/580 102/18722 0.959994113293846 0.967273098121681 ACSS1 1 GO:0046474 glycerophospholipid biosynthetic process 3/580 211/18722 0.961050082896431 0.968127341466602 GPAA1/TMEM150A/PISD 3 GO:0032006 regulation of TOR signaling 1/580 104/18722 0.962447672146019 0.969325275693186 SLC38A9 1 GO:0051321 meiotic cell cycle 4/580 261/18722 0.96306736717144 0.969739407818655 DUSP1/SLC2A8/ATRX/ASPM 4 GO:0002377 immunoglobulin production 3/580 216/18722 0.965398745360382 0.971876529149597 PRKDC/TFRC/XBP1 3 GO:0051607 defense response to virus 4/580 265/18722 0.966149769070962 0.972211721321732 IL10RB/PMAIP1/PUM1/EIF2AK4 4 GO:0140546 defense response to symbiont 4/580 265/18722 0.966149769070962 0.972211721321732 IL10RB/PMAIP1/PUM1/EIF2AK4 4 GO:0009063 cellular amino acid catabolic process 1/580 110/18722 0.968943125246666 0.974811697062999 GLDC 1 GO:0015718 monocarboxylic acid transport 1/580 111/18722 0.969910941029867 0.975502913722695 SLC16A12 1 GO:0006959 humoral immune response 5/580 317/18722 0.97004966157116 0.975502913722695 GAPDH/CD46/CD81/CD55/S100A9 5 GO:0048469 cell maturation 2/580 171/18722 0.970742536737835 0.975884387139473 APP/TYMS 2 GO:0002526 acute inflammatory response 1/580 112/18722 0.970848647450945 0.975884387139473 IL6ST 1 GO:0001578 microtubule bundle formation 1/580 113/18722 0.97175717966365 0.97637559788629 CLIP1 1 GO:0071347 cellular response to interleukin-1 1/580 113/18722 0.97175717966365 0.97637559788629 EGR1 1 GO:0045055 regulated exocytosis 3/580 230/18722 0.975267610871799 0.979691070877913 CALM1/VAMP2/GNAI2 3 GO:0140013 meiotic nuclear division 2/580 185/18722 0.979935379537483 0.984167447684913 SLC2A8/ASPM 2 GO:0002429 immune response-activating cell surface receptor signaling pathway 4/580 291/18722 0.981028836959242 0.984627777448734 SLC39A10/KCNN4/CD81/PHPT1 4 GO:0002757 immune response-activating signal transduction 4/580 291/18722 0.981028836959242 0.984627777448734 SLC39A10/KCNN4/CD81/PHPT1 4 GO:0016236 macroautophagy 4/580 291/18722 0.981028836959242 0.984627777448734 GAPDH/UFL1/CALM1/VDAC1 4 GO:0006911 phagocytosis, engulfment 1/580 127/18722 0.981873241540122 0.98526266373314 CDC42 1 GO:0007127 meiosis I 1/580 129/18722 0.98298642564909 0.986166925300672 SLC2A8 1 GO:1901605 alpha-amino acid metabolic process 2/580 195/18722 0.984717055273134 0.987690106550646 GLDC/ILVBL 2 GO:0042742 defense response to bacterium 5/580 350/18722 0.98507130477674 0.98783239295313 GRN/S100A9/PLAC8/HMGB2/CYBA 5 GO:0045017 glycerolipid biosynthetic process 3/580 252/18722 0.985576867726984 0.988039359226358 GPAA1/TMEM150A/PISD 3 GO:0006887 exocytosis 5/580 352/18722 0.985702564353967 0.988039359226358 ATP6AP1/CALM1/VAMP2/GNAI2/RAB11A 5 GO:0061982 meiosis I cell cycle process 1/580 135/18722 0.985932926459567 0.988057324060212 SLC2A8 1 GO:0016579 protein deubiquitination 1/580 139/18722 0.987608396625105 0.989523191017528 CDK1 1 GO:0090305 nucleic acid phosphodiester bond hydrolysis 3/580 261/18722 0.988475088996019 0.99017825520579 RPS21/N4BP2/PLD3 3 GO:0002768 immune response-regulating cell surface receptor signaling pathway 4/580 315/18722 0.989076100226344 0.990566955674574 SLC39A10/KCNN4/CD81/PHPT1 4 GO:0090501 RNA phosphodiester bond hydrolysis 1/580 152/18722 0.991795606931491 0.993076720740229 RPS21 1 GO:0046434 organophosphate catabolic process 1/580 155/18722 0.9925406329873 0.99360879983296 DUT 1 GO:0070646 protein modification by small protein removal 1/580 157/18722 0.992999400770497 0.99385414525147 CDK1 1 GO:0060271 cilium assembly 4/580 337/18722 0.993498731374316 0.993987617577544 LAMA5/GALNT11/E2F4/DYNLL1 4 GO:0006520 cellular amino acid metabolic process 3/580 284/18722 0.993560187941949 0.993987617577544 GLDC/ILVBL/IARS2 3 GO:0006399 tRNA metabolic process 1/580 179/18722 0.996519019747445 0.996733324912982 IARS2 1 GO:0044782 cilium organization 4/580 368/18722 0.996928572841661 0.996928572841661 LAMA5/GALNT11/E2F4/DYNLL1 4