ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0034329 cell junction assembly 30/389 420/18722 4.54195144832974e-09 1.65644969320586e-05 ITGB4/PRKCH/DST/EPHB3/FZD5/MARVELD3/MYO9A/GJA1/CLDN4/TJP1/CDH1/LRP1/FBXO45/JAM3/ITGA6/NRP1/TPBG/CLDN3/ABL1/MMP14/FERMT2/EPB41L3/CTNND1/LAMC1/PLXNB1/LSR/MPP7/RAPGEF2/MYO1C/PTK2 30 GO:0035633 maintenance of blood-brain barrier 8/389 35/18722 4.65668438227289e-07 0.000849146397107461 GJA1/TJP1/JAM3/CLDN3/TJP2/LAMC1/LSR/DMD 8 GO:0120193 tight junction organization 11/389 80/18722 7.84808532221048e-07 0.000897640588802834 PRKCH/FZD5/MARVELD3/GJA1/CLDN4/TJP1/CLDN3/SVEP1/LSR/MPP7/MYO1C 11 GO:0045216 cell-cell junction organization 17/389 200/18722 1.01455186238071e-06 0.000897640588802834 PRKCH/FZD5/MARVELD3/GJA1/CLDN4/TJP1/CDH1/JAM3/CLDN3/FERMT2/SVEP1/TJP2/EPB41L3/CTNND1/LSR/MPP7/MYO1C 17 GO:0010720 positive regulation of cell development 21/389 298/18722 1.23065614039325e-06 0.000897640588802834 ASPM/LRP2/PRKCH/DAG1/FZD3/GLI3/LRP1/RAC3/STK25/NRP1/DOCK5/ABL1/FERMT2/PLXNB1/CDKL3/SERPINE2/TRIB1/CYFIP1/SPINT1/IL6ST/EGFR 21 GO:0120192 tight junction assembly 10/389 74/18722 2.93831220066687e-06 0.00178600409930534 PRKCH/FZD5/MARVELD3/GJA1/CLDN4/TJP1/CLDN3/LSR/MPP7/MYO1C 10 GO:0048732 gland development 25/389 436/18722 5.15608517191121e-06 0.00264086031250725 MET/EPHB3/ELK1/ELF3/MPST/LRP5/COBL/WLS/DAG1/CDH1/GLI3/TFCP2L1/NRP1/KDM5B/ABL1/FGFR2/LSR/PCNA/SERPINE2/LAMA5/CEBPA/EZH2/PRLR/EGFR/XBP1 25 GO:2000810 regulation of bicellular tight junction assembly 6/389 23/18722 5.79294831369838e-06 0.00264086031250725 PRKCH/FZD5/GJA1/TJP1/CLDN3/MYO1C 6 GO:0050767 regulation of neurogenesis 22/389 364/18722 8.39411512887233e-06 0.00340148198611082 ASPM/LRP2/PRKCH/SEMA4G/SEMA6A/DAG1/FZD3/GLI3/LRP1/STK25/YAP1/NRP1/PLXNB1/CDKL3/SERPINE2/CYFIP1/RAPGEF2/EZH2/SPINT1/IL6ST/BHLHE41/EGFR 22 GO:0007043 cell-cell junction assembly 13/389 146/18722 1.15368817116404e-05 0.00420750076023526 PRKCH/FZD5/MARVELD3/GJA1/CLDN4/TJP1/JAM3/CLDN3/EPB41L3/CTNND1/LSR/MPP7/MYO1C 13 GO:0070830 bicellular tight junction assembly 9/389 70/18722 1.39781687980515e-05 0.00427212617312041 PRKCH/FZD5/MARVELD3/GJA1/CLDN4/TJP1/CLDN3/MPP7/MYO1C 9 GO:0007229 integrin-mediated signaling pathway 11/389 107/18722 1.40686226016751e-05 0.00427212617312041 ITGB4/DST/ADAMTS1/ITGA6/NRP1/ABL1/FERMT2/ITGB5/LAMA5/ITGAV/PTK2 11 GO:0034446 substrate adhesion-dependent cell spreading 11/389 108/18722 1.53767816147077e-05 0.00427212617312041 EPHB3/EPHA1/RAC3/NRP1/DOCK5/ABL1/FERMT2/LAMC1/LAMA5/ITGAV/PTK2 11 GO:0051962 positive regulation of nervous system development 18/389 272/18722 1.67428672595524e-05 0.00427212617312041 ASPM/LRP2/PRKCH/EPHB3/DAG1/FZD3/GLI3/LRP1/STK25/NRP1/TPBG/PLXNB1/CDKL3/SERPINE2/CYFIP1/SPINT1/IL6ST/EGFR 18 GO:0045667 regulation of osteoblast differentiation 12/389 132/18722 2.02804021981524e-05 0.00427212617312041 BAMBI/PPARG/LRP5/ACVR2A/GLI3/YAP1/FBN2/FERMT2/FGFR2/CEBPA/PTK2/IL6ST 12 GO:0051960 regulation of nervous system development 24/389 443/18722 2.03277054533034e-05 0.00427212617312041 ASPM/LRP2/PRKCH/EPHB3/SEMA4G/SEMA6A/DAG1/FZD3/GLI3/LRP1/STK25/YAP1/NRP1/TPBG/PLXNB1/CDKL3/SERPINE2/CYFIP1/RAPGEF2/EZH2/SPINT1/IL6ST/BHLHE41/EGFR 24 GO:0050769 positive regulation of neurogenesis 16/389 225/18722 2.04637398022944e-05 0.00427212617312041 ASPM/LRP2/PRKCH/DAG1/FZD3/GLI3/LRP1/STK25/NRP1/PLXNB1/CDKL3/SERPINE2/CYFIP1/SPINT1/IL6ST/EGFR 16 GO:0016055 Wnt signaling pathway 24/389 444/18722 2.10853499084638e-05 0.00427212617312041 ASPM/DCDC2/LGR5/BAMBI/NDRG2/PYGO1/FZD5/ARL6/LRP5/RNF43/WLS/FZD3/GLI3/LRP1/RAC3/YAP1/TPBG/ABL1/FERMT2/TMEM170B/CTNND1/FGFR2/STK3/EGFR 24 GO:0198738 cell-cell signaling by wnt 24/389 446/18722 2.26776982559727e-05 0.00429381233569343 ASPM/DCDC2/LGR5/BAMBI/NDRG2/PYGO1/FZD5/ARL6/LRP5/RNF43/WLS/FZD3/GLI3/LRP1/RAC3/YAP1/TPBG/ABL1/FERMT2/TMEM170B/CTNND1/FGFR2/STK3/EGFR 24 GO:1901888 regulation of cell junction assembly 15/389 204/18722 2.50570152177049e-05 0.00429381233569343 PRKCH/EPHB3/FZD5/GJA1/TJP1/LRP1/NRP1/TPBG/CLDN3/ABL1/MMP14/FERMT2/RAPGEF2/MYO1C/PTK2 15 GO:0031589 cell-substrate adhesion 21/389 363/18722 2.58162473578375e-05 0.00429381233569343 CCDC80/ITGB4/PLAU/EPHB3/EPHA1/DAG1/LRP1/JAM3/RAC3/GCNT2/ITGA6/NRP1/DOCK5/ABL1/MMP14/FERMT2/LAMC1/ITGB5/LAMA5/ITGAV/PTK2 21 GO:0042060 wound healing 23/389 422/18722 2.75237965922609e-05 0.00429381233569343 F5/DST/PLAU/SLC7A11/GJA1/CLDN4/DAG1/GLI3/DCBLD2/YAP1/CLDN3/FERMT2/FGFR2/HMGCR/SERPINE2/MYOF/ERBB3/GGCX/PTK2/IL6ST/EGFR/XBP1/ANO6 23 GO:0007044 cell-substrate junction assembly 10/389 95/18722 2.8076869713724e-05 0.00429381233569343 ITGB4/DST/LRP1/ITGA6/NRP1/ABL1/MMP14/FERMT2/LAMC1/PTK2 10 GO:0061138 morphogenesis of a branching epithelium 14/389 182/18722 2.82565111205491e-05 0.00429381233569343 MET/COL4A1/FZD5/LRP5/DAG1/GLI3/YAP1/NRP1/KDM5B/ABL1/MMP14/FGFR2/LAMA5/SPINT1 14 GO:0021675 nerve development 9/389 77/18722 3.05146425841652e-05 0.00445147606017802 SLC1A3/CTSV/DAG1/GLI3/LRIG2/FBXO45/NRP1/SERPINE2/ERBB3 9 GO:0043297 apical junction assembly 9/389 78/18722 3.38712398708579e-05 0.00475109276188534 PRKCH/FZD5/MARVELD3/GJA1/CLDN4/TJP1/CLDN3/MPP7/MYO1C 9 GO:0150115 cell-substrate junction organization 10/389 101/18722 4.78103968652062e-05 0.00645794508768174 ITGB4/DST/LRP1/ITGA6/NRP1/ABL1/MMP14/FERMT2/LAMC1/PTK2 10 GO:0060562 epithelial tube morphogenesis 19/389 325/18722 5.41785076923085e-05 0.00705675062692318 MET/LRP2/LGR5/COL4A1/LRP5/COBL/DAG1/FZD3/GLI3/YAP1/NRP1/KDM5B/ABL1/MMP14/FGFR2/LAMA5/AHI1/SPINT1/STK3 19 GO:0001763 morphogenesis of a branching structure 14/389 196/18722 6.37219873894442e-05 0.00766276895693467 MET/COL4A1/FZD5/LRP5/DAG1/GLI3/YAP1/NRP1/KDM5B/ABL1/MMP14/FGFR2/LAMA5/SPINT1 14 GO:0048736 appendage development 13/389 172/18722 6.51345866917946e-05 0.00766276895693467 ITGB4/SLC7A11/LRP5/NR2F2/GLI3/ITGA6/FBN2/FERMT2/ZNF219/FGFR2/MED31/SLC39A1/CHST11 13 GO:0060173 limb development 13/389 172/18722 6.51345866917946e-05 0.00766276895693467 ITGB4/SLC7A11/LRP5/NR2F2/GLI3/ITGA6/FBN2/FERMT2/ZNF219/FGFR2/MED31/SLC39A1/CHST11 13 GO:0048754 branching morphogenesis of an epithelial tube 12/389 151/18722 7.64893727397932e-05 0.00871739819943831 MET/COL4A1/LRP5/DAG1/GLI3/YAP1/NRP1/KDM5B/ABL1/MMP14/FGFR2/LAMA5 12 GO:0045669 positive regulation of osteoblast differentiation 8/389 69/18722 8.93973372086921e-05 0.0098797602666697 LRP5/ACVR2A/GLI3/YAP1/FBN2/FERMT2/CEBPA/IL6ST 8 GO:0001649 osteoblast differentiation 15/389 229/18722 9.41891794722654e-05 0.0101031746333927 BAMBI/PPARG/LRP5/ACVR2A/GLI3/YAP1/FBN2/FERMT2/FGFR2/MRC2/RRBP1/CEBPA/PTK2/FHL2/IL6ST 15 GO:0061564 axon development 23/389 467/18722 0.000128031827893617 0.0133409164665149 EPHB3/EPHA1/SEMA4G/SEMA6A/EPHB4/COBL/DAG1/FZD3/GLI3/NREP/LRP1/LRIG2/FBXO45/JAM3/STK25/NRP1/ABL1/FGFR2/PLXNB1/CDKL3/LAMA5/CYFIP1/PTK2 23 GO:0021987 cerebral cortex development 10/389 114/18722 0.000133426429636267 0.0135168385800963 ASPM/MBOAT7/GLI3/LRP1/BTBD3/TACC2/FBXO45/GNG12/SLC2A1/ADGRG1 10 GO:0030900 forebrain development 20/389 379/18722 0.000141348867803585 0.013932414077829 ASPM/LRP2/EPHB3/SLC7A11/MBOAT7/NR2F2/CDH1/GLI3/LRP1/BTBD3/TACC2/FBXO45/RAC3/NRP1/FGFR2/GNG12/RAPGEF2/EZH2/SLC2A1/ADGRG1 20 GO:0030166 proteoglycan biosynthetic process 7/389 56/18722 0.000152865239778459 0.0146710402492642 CYTL1/CHPF/GLCE/HS6ST2/EXTL2/CHST11/CHST14 7 GO:0001894 tissue homeostasis 16/389 268/18722 0.000163754232902233 0.0153131201896011 CYTL1/PBLD/GJA1/TJP1/JAM3/RAC3/TFRC/GCNT2/YAP1/CLDN3/TJP2/LAMC1/LSR/DMD/SLC2A1/EGFR 16 GO:1903034 regulation of response to wounding 12/389 167/18722 0.00019898678003266 0.0173082920465827 PLAU/GJA1/CLDN4/LRP1/LRIG2/CLDN3/FERMT2/HMGCR/SERPINE2/PTK2/XBP1/ANO6 12 GO:0030198 extracellular matrix organization 17/389 301/18722 0.000200305239322072 0.0173082920465827 CCDC80/COL14A1/MMP15/COL4A1/TLL1/ADAMTS1/ELF3/COL4A2/CTSV/DAG1/LRP1/ABL1/MMP14/ADAMTSL4/LAMC1/SERAC1/SPINT1 17 GO:0042063 gliogenesis 17/389 301/18722 0.000200305239322072 0.0173082920465827 LRP2/ITGB4/PRKCH/MBOAT7/DAG1/GLI3/LRP1/ABL1/MMP14/SERPINE2/ERBB3/EZH2/SPINT1/IL6ST/ADGRG1/EGFR/GPC1 17 GO:0043062 extracellular structure organization 17/389 302/18722 0.000208301390862709 0.0173082920465827 CCDC80/COL14A1/MMP15/COL4A1/TLL1/ADAMTS1/ELF3/COL4A2/CTSV/DAG1/LRP1/ABL1/MMP14/ADAMTSL4/LAMC1/SERAC1/SPINT1 17 GO:0033688 regulation of osteoblast proliferation 5/389 27/18722 0.000208973966834509 0.0173082920465827 LRP5/ABL1/FGFR2/PLXNB1/ITGAV 5 GO:0042176 regulation of protein catabolic process 20/389 391/18722 0.000213565435178563 0.0173082920465827 LRP2/RHBDF1/GJA1/CDH1/LRP1/HGS/LRIG2/HACE1/TMTC3/HMGCR/USP5/MAGEF1/SERPINE2/FZR1/TRIB1/CEBPA/PTK2/EGFR/PSMD2/RNF19B 20 GO:0045229 external encapsulating structure organization 17/389 304/18722 0.00022513213893528 0.0175861403820309 CCDC80/COL14A1/MMP15/COL4A1/TLL1/ADAMTS1/ELF3/COL4A2/CTSV/DAG1/LRP1/ABL1/MMP14/ADAMTSL4/LAMC1/SERAC1/SPINT1 17 GO:0010810 regulation of cell-substrate adhesion 14/389 221/18722 0.000226637948438566 0.0175861403820309 CCDC80/PLAU/EPHA1/DAG1/LRP1/RAC3/GCNT2/ITGA6/NRP1/DOCK5/ABL1/MMP14/FERMT2/PTK2 14 GO:0006029 proteoglycan metabolic process 8/389 79/18722 0.000232954983176818 0.017699725492622 CYTL1/CHPF/GLCE/HS6ST2/EXTL2/CHST11/CHST14/GPC1 8 GO:0071560 cellular response to transforming growth factor beta stimulus 15/389 250/18722 0.000246776040962948 0.0183671881916709 ZFYVE9/LTBP1/BAMBI/PBLD/SPRED2/PPARG/COL4A2/NREP/GCNT2/FBN2/FERMT2/FGFR2/ITGB5/PTK2/CHST11 15 GO:0001889 liver development 11/389 147/18722 0.000256584921873481 0.0187153042014517 MET/ELK1/MPST/COBL/GLI3/LSR/PCNA/CEBPA/EZH2/EGFR/XBP1 11 GO:0007179 transforming growth factor beta receptor signaling pathway 13/389 198/18722 0.00026645175432192 0.0190539127061185 ZFYVE9/LTBP1/BAMBI/PBLD/SPRED2/PPARG/NREP/GCNT2/FBN2/FERMT2/ITGB5/PTK2/CHST11 13 GO:0022604 regulation of cell morphogenesis 17/389 309/18722 0.000272485610346975 0.0191106734795273 BAMBI/SYT1/MYO9A/CLDN4/DAG1/CDC42EP4/RAC3/NRP1/CLDN3/DOCK5/ABL1/FERMT2/EPB41L3/PLXNB1/CDKL3/CYFIP1/PTK2 17 GO:0007411 axon guidance 14/389 227/18722 0.00029822613237807 0.0203511791904384 EPHB3/EPHA1/SEMA4G/SEMA6A/EPHB4/DAG1/FZD3/GLI3/LRP1/NRP1/PLXNB1/LAMA5/CYFIP1/PTK2 14 GO:0061008 hepaticobiliary system development 11/389 150/18722 0.00030561527303185 0.0203511791904384 MET/ELK1/MPST/COBL/GLI3/LSR/PCNA/CEBPA/EZH2/EGFR/XBP1 11 GO:0097485 neuron projection guidance 14/389 228/18722 0.000311869077838384 0.0203511791904384 EPHB3/EPHA1/SEMA4G/SEMA6A/EPHB4/DAG1/FZD3/GLI3/LRP1/NRP1/PLXNB1/LAMA5/CYFIP1/PTK2 14 GO:0035272 exocrine system development 6/389 45/18722 0.000317862386978738 0.0203511791904384 WLS/DAG1/TFCP2L1/NRP1/FGFR2/LAMA5 6 GO:0071559 response to transforming growth factor beta 15/389 256/18722 0.000318074366288728 0.0203511791904384 ZFYVE9/LTBP1/BAMBI/PBLD/SPRED2/PPARG/COL4A2/NREP/GCNT2/FBN2/FERMT2/FGFR2/ITGB5/PTK2/CHST11 15 GO:0060249 anatomical structure homeostasis 17/389 314/18722 0.00032826402883668 0.0206410157442651 CYTL1/PBLD/GJA1/TJP1/JAM3/RAC3/TFRC/GCNT2/YAP1/CLDN3/TJP2/LAMC1/LSR/TMEM175/DMD/SLC2A1/EGFR 17 GO:0001503 ossification 20/389 408/18722 0.000370621392075727 0.0229094274050877 BAMBI/PPARG/LRP5/ACVR2A/GLI3/YAP1/FBN2/MMP14/FERMT2/SLC26A2/FGFR2/MRC2/RRBP1/PLXNB1/CEBPA/PTK2/FHL2/IL6ST/EGFR/ANO6 20 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 10/389 131/18722 0.000414256504492315 0.0251798911980579 LRP2/LTBP1/BAMBI/PBLD/SPRED2/PPARG/LRP1/FBN2/ABL1/CHST11 10 GO:0014015 positive regulation of gliogenesis 7/389 66/18722 0.000429796591853252 0.02569619951621 LRP2/PRKCH/DAG1/SERPINE2/SPINT1/IL6ST/EGFR 7 GO:0010975 regulation of neuron projection development 21/389 445/18722 0.00044032978694729 0.0259013344031737 EPHB3/LZTS1/SEMA4G/SEMA6A/COBL/CBFA2T2/LRP1/LRIG2/SCARB2/ITGA6/STK25/NRP1/PLXNB1/CDKL3/P3H1/TENM3/CYFIP1/RAPGEF2/CAMK2G/EZH2/FKBP4 21 GO:0033687 osteoblast proliferation 5/389 32/18722 0.000478682487329164 0.0277103973220549 LRP5/ABL1/FGFR2/PLXNB1/ITGAV 5 GO:0061041 regulation of wound healing 10/389 134/18722 0.000495805429579735 0.0280275829879944 PLAU/GJA1/CLDN4/CLDN3/FERMT2/HMGCR/SERPINE2/PTK2/XBP1/ANO6 10 GO:0007409 axonogenesis 20/389 418/18722 0.000503872997057455 0.0280275829879944 EPHB3/EPHA1/SEMA4G/SEMA6A/EPHB4/COBL/DAG1/FZD3/GLI3/LRP1/FBXO45/STK25/NRP1/ABL1/FGFR2/PLXNB1/CDKL3/LAMA5/CYFIP1/PTK2 20 GO:0007369 gastrulation 12/389 185/18722 0.000507217021444373 0.0280275829879944 ITGB4/MMP15/COL4A2/LRP5/ACVR2A/GJA1/WLS/DAG1/MMP14/FGFR2/ITGB5/ITGAV 12 GO:0055123 digestive system development 10/389 137/18722 0.000590243527818164 0.0321286290440723 EPHB3/COBL/WLS/GLI3/CBFA2T2/YAP1/FGFR2/AHI1/IL6ST/EGFR 10 GO:0048608 reproductive structure development 20/389 424/18722 0.000602360529604911 0.0323060125216046 ASPM/LRP2/FZD5/ADAMTS1/PPARG/CTSV/ACVR2A/NR2F2/GJA1/GLI3/ZFX/KDM5B/MMP14/FGFR2/SERPINE2/CEBPA/SPINT1/STK3/PTK2/ADGRG1 20 GO:0060070 canonical Wnt signaling pathway 16/389 303/18722 0.000639163469088345 0.0328782220009754 ASPM/LGR5/BAMBI/PYGO1/FZD5/LRP5/WLS/FZD3/GLI3/YAP1/TPBG/TMEM170B/CTNND1/FGFR2/STK3/EGFR 16 GO:0007431 salivary gland development 5/389 34/18722 0.000639298645473032 0.0328782220009754 DAG1/TFCP2L1/NRP1/FGFR2/LAMA5 5 GO:0098656 anion transmembrane transport 14/389 245/18722 0.000640075065003907 0.0328782220009754 LRP2/GABRE/SLC7A11/ANO2/SLC1A3/GJA1/SLC38A9/PCYOX1/SLC26A2/SLC25A11/TCAF1/SLC16A1/SLC25A4/ANO6 14 GO:0061458 reproductive system development 20/389 427/18722 0.000657571779768832 0.0330810482137302 ASPM/LRP2/FZD5/ADAMTS1/PPARG/CTSV/ACVR2A/NR2F2/GJA1/GLI3/ZFX/KDM5B/MMP14/FGFR2/SERPINE2/CEBPA/SPINT1/STK3/PTK2/ADGRG1 20 GO:0090287 regulation of cellular response to growth factor stimulus 16/389 304/18722 0.000662165209652401 0.0330810482137302 LRP2/LTBP1/BAMBI/PBLD/SPRED2/SEMA6A/PPARG/NREP/HGS/WASF1/FBN2/ABL1/CYFIP1/MYO1C/CHST11/GPC1 16 GO:1903829 positive regulation of cellular protein localization 15/389 276/18722 0.000697821232952413 0.0343912707645601 PRKCH/FZD5/CDH1/GLI3/LRP1/LRIG2/TFRC/YAP1/FERMT2/CLN3/MIEF2/TCAF1/TM9SF4/MYO1C/EGFR 15 GO:0033627 cell adhesion mediated by integrin 7/389 72/18722 0.000730992332293744 0.0347304998077502 ITGB4/PLAU/JAM3/RAC3/ITGB5/ITGAV/PTK2 7 GO:1903036 positive regulation of response to wounding 7/389 72/18722 0.000730992332293744 0.0347304998077502 CLDN4/LRP1/CLDN3/FERMT2/PTK2/XBP1/ANO6 7 GO:0000731 DNA synthesis involved in DNA repair 5/389 35/18722 0.000733273508416992 0.0347304998077502 USP43/POLI/WRNIP1/PCNA/SPRTN 5 GO:1902414 protein localization to cell junction 8/389 94/18722 0.000759272545121945 0.0355008586161504 MARVELD3/DAG1/TJP1/JAM3/FERMT2/TJP2/LSR/MPP7 8 GO:0022612 gland morphogenesis 9/389 118/18722 0.000802847251736779 0.0367187849841336 ELF3/LRP5/DAG1/GLI3/NRP1/KDM5B/FGFR2/LAMA5/XBP1 9 GO:0019985 translesion synthesis 4/389 21/18722 0.000829919506015602 0.0367187849841336 USP43/POLI/PCNA/SPRTN 4 GO:0060445 branching involved in salivary gland morphogenesis 4/389 21/18722 0.000829919506015602 0.0367187849841336 DAG1/NRP1/FGFR2/LAMA5 4 GO:0150105 protein localization to cell-cell junction 4/389 21/18722 0.000829919506015602 0.0367187849841336 TJP1/TJP2/LSR/MPP7 4 GO:0021543 pallium development 11/389 169/18722 0.000835661956041429 0.0367187849841336 ASPM/MBOAT7/GLI3/LRP1/BTBD3/TACC2/FBXO45/GNG12/EZH2/SLC2A1/ADGRG1 11 GO:0072348 sulfur compound transport 6/389 54/18722 0.000861622692173891 0.0373056111076035 SLC7A11/SLC19A3/GJA1/RACGAP1/SLC26A2/SLC25A11 6 GO:0001890 placenta development 10/389 144/18722 0.00086947544396663 0.0373056111076035 FZD5/PPARG/CTSV/NR2F2/GJA1/FGFR2/CEBPA/SPINT1/STK3/PTK2 10 GO:0051495 positive regulation of cytoskeleton organization 13/389 226/18722 0.000930874730252106 0.0394755830375515 MET/EPHA1/WASF1/CDC42EP4/NRP1/ABL1/FERMT2/TRIM27/ARL3/CLIP1/CYFIP1/DYNC1H1/MYO1C 13 GO:0061299 retina vasculature morphogenesis in camera-type eye 3/389 10/18722 0.000958181149110154 0.0398198092036832 COL4A1/LRP5/NRP1 3 GO:0001704 formation of primary germ layer 9/389 121/18722 0.000960828958026904 0.0398198092036832 ITGB4/MMP15/COL4A2/GJA1/WLS/MMP14/FGFR2/ITGB5/ITGAV 9 GO:0099563 modification of synaptic structure 4/389 22/18722 0.000997846528440778 0.0408892841485788 WASF1/ABL1/CLN3/CYFIP1 4 GO:0048008 platelet-derived growth factor receptor signaling pathway 6/389 56/18722 0.00104616590022984 0.0423929670904246 PDGFRL/LRP1/HGS/LRIG2/NRP1/ABL1 6 GO:0010811 positive regulation of cell-substrate adhesion 9/389 123/18722 0.00107950649759823 0.0432632988652827 CCDC80/EPHA1/DAG1/RAC3/ITGA6/NRP1/DOCK5/ABL1/FERMT2 9 GO:1905475 regulation of protein localization to membrane 11/389 175/18722 0.00111162814764238 0.0440663897223018 PRKCH/SLC7A11/DAG1/LRP1/MMP14/CLN3/MIEF2/TCAF1/MYO1C/EGFR/GPC1 11 GO:1900024 regulation of substrate adhesion-dependent cell spreading 6/389 57/18722 0.00114910371087664 0.0450621638017969 RAC3/NRP1/DOCK5/ABL1/FERMT2/PTK2 6 GO:0060384 innervation 4/389 23/18722 0.00118828513003317 0.0461029347790528 LRIG2/FBXO45/NRP1/SERPINE2 4 GO:0007160 cell-matrix adhesion 13/389 233/18722 0.00122887552200539 0.0471758845131964 ITGB4/PLAU/EPHA1/DAG1/LRP1/JAM3/NRP1/ABL1/MMP14/FERMT2/ITGB5/ITGAV/PTK2 13 GO:0060560 developmental growth involved in morphogenesis 13/389 234/18722 0.00127730987685634 0.0474951798520481 SEMA4G/SYT1/SEMA6A/COBL/LRP1/WASF1/YAP1/NRP1/KDM5B/ABL1/FGFR2/CDKL3/CYFIP1 13 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 17/389 355/18722 0.00129075987920937 0.0474951798520481 LRP2/ZFYVE9/LTBP1/BAMBI/PBLD/SPRED2/PPARG/ACVR2A/NREP/LRP1/GCNT2/FBN2/ABL1/FERMT2/ITGB5/PTK2/CHST11 17 GO:0033690 positive regulation of osteoblast proliferation 3/389 11/18722 0.00129726815606323 0.0474951798520481 LRP5/ABL1/ITGAV 3 GO:0071679 commissural neuron axon guidance 3/389 11/18722 0.00129726815606323 0.0474951798520481 DAG1/FZD3/NRP1 3 GO:0048565 digestive tract development 9/389 127/18722 0.00135245762432651 0.0474951798520481 EPHB3/COBL/GLI3/CBFA2T2/YAP1/FGFR2/AHI1/IL6ST/EGFR 9 GO:0009069 serine family amino acid metabolic process 5/389 40/18722 0.00136533956425881 0.0474951798520481 SLC7A11/MPST/SEPHS1/GLDC/SHMT1 5 GO:0035329 hippo signaling 5/389 40/18722 0.00136533956425881 0.0474951798520481 WWC1/TEAD1/YAP1/WWC3/STK3 5 GO:0071526 semaphorin-plexin signaling pathway 5/389 40/18722 0.00136533956425881 0.0474951798520481 MET/SEMA4G/SEMA6A/NRP1/PLXNB1 5 GO:0006767 water-soluble vitamin metabolic process 6/389 59/18722 0.00137808888148611 0.0474951798520481 SLC19A3/BTD/SHMT1/MMAB/MTHFD2L/SLC2A1 6 GO:0090303 positive regulation of wound healing 6/389 59/18722 0.00137808888148611 0.0474951798520481 CLDN4/CLDN3/FERMT2/PTK2/XBP1/ANO6 6 GO:0014013 regulation of gliogenesis 8/389 103/18722 0.00138044668613027 0.0474951798520481 LRP2/PRKCH/DAG1/SERPINE2/EZH2/SPINT1/IL6ST/EGFR 8 GO:0001952 regulation of cell-matrix adhesion 9/389 128/18722 0.00142871347329617 0.048696430253375 PLAU/EPHA1/DAG1/LRP1/NRP1/ABL1/MMP14/FERMT2/PTK2 9 GO:0030111 regulation of Wnt signaling pathway 16/389 328/18722 0.00146926279982712 0.0487944898375583 ASPM/DCDC2/LGR5/BAMBI/RNF43/WLS/GLI3/LRP1/YAP1/TPBG/ABL1/TMEM170B/CTNND1/FGFR2/STK3/EGFR 16 GO:1902905 positive regulation of supramolecular fiber organization 12/389 209/18722 0.001469596294855 0.0487944898375583 MET/EPHA1/WASF1/CDC42EP4/NRP1/ABL1/FERMT2/TRIM27/ARL3/CLIP1/CYFIP1/MYO1C 12 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 7/389 81/18722 0.00147172851168945 0.0487944898375583 LTBP1/BAMBI/PBLD/SPRED2/PPARG/FBN2/CHST11 7 GO:1903364 positive regulation of cellular protein catabolic process 10/389 155/18722 0.00152058232220843 0.0497826934546432 LRP2/LRP1/TMTC3/USP5/MAGEF1/FZR1/TRIB1/CEBPA/PTK2/RNF19B 10 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 5/389 41/18722 0.00152883511568962 0.0497826934546432 RAC3/NRP1/DOCK5/ABL1/FERMT2 5 GO:0070371 ERK1 and ERK2 cascade 16/389 330/18722 0.00156356676567189 0.0504630795965078 C3orf33/NDRG2/SPRED2/SEMA6A/LRP1/GCNT2/NRP1/TPBG/ABL1/FERMT2/FGFR2/HMGCR/RAPGEF2/ITGAV/EGFR/SHC1 16 GO:0001764 neuron migration 10/389 156/18722 0.00159544448982043 0.05104022854715 ASPM/DCDC2/SEMA6A/NR2F2/FZD3/LRIG2/FBXO45/NRP1/RAPGEF2/ADGRG1 10 GO:0090385 phagosome-lysosome fusion 3/389 12/18722 0.00170315811637515 0.0535467038829325 RAB7B/CLN3/TMEM175 3 GO:0090557 establishment of endothelial intestinal barrier 3/389 12/18722 0.00170315811637515 0.0535467038829325 TJP1/TJP2/RAPGEF2 3 GO:0060443 mammary gland morphogenesis 5/389 43/18722 0.00189837534431501 0.059174144279631 ELF3/LRP5/GLI3/KDM5B/FGFR2 5 GO:0021537 telencephalon development 13/389 248/18722 0.00214014283769081 0.0651730117896771 ASPM/EPHB3/SLC7A11/MBOAT7/GLI3/LRP1/BTBD3/TACC2/FBXO45/GNG12/EZH2/SLC2A1/ADGRG1 13 GO:0070372 regulation of ERK1 and ERK2 cascade 15/389 309/18722 0.00214155340748652 0.0651730117896771 C3orf33/NDRG2/SPRED2/SEMA6A/LRP1/GCNT2/NRP1/TPBG/ABL1/FERMT2/FGFR2/HMGCR/RAPGEF2/EGFR/SHC1 15 GO:0021819 layer formation in cerebral cortex 3/389 13/18722 0.0021801775262793 0.0651730117896771 MBOAT7/GLI3/ADGRG1 3 GO:0060670 branching involved in labyrinthine layer morphogenesis 3/389 13/18722 0.0021801775262793 0.0651730117896771 FZD5/FGFR2/SPINT1 3 GO:1905244 regulation of modification of synaptic structure 3/389 13/18722 0.0021801775262793 0.0651730117896771 ABL1/CLN3/CYFIP1 3 GO:0010976 positive regulation of neuron projection development 10/389 163/18722 0.00220728887886003 0.0654470125301018 COBL/CBFA2T2/LRP1/SCARB2/ITGA6/P3H1/TENM3/CYFIP1/RAPGEF2/EZH2 10 GO:0035987 endodermal cell differentiation 5/389 45/18722 0.00232931104954551 0.0685080435297779 MMP15/COL4A2/MMP14/ITGB5/ITGAV 5 GO:0048640 negative regulation of developmental growth 8/389 112/18722 0.00235084182808873 0.0685881611763167 WWC1/SEMA4G/SEMA6A/GJA1/NRP1/CDKL3/WWC3/STK3 8 GO:0010232 vascular transport 7/389 88/18722 0.0023750203488679 0.0687436445422319 LRP2/SLC1A3/GJA1/LRP1/TFRC/SLC16A1/SLC2A1 7 GO:0045600 positive regulation of fat cell differentiation 6/389 66/18722 0.00246141980680251 0.0690522925800673 CDS1/PPARG/LRP5/CEBPA/STK3/XBP1 6 GO:0051893 regulation of focal adhesion assembly 6/389 66/18722 0.00246141980680251 0.0690522925800673 LRP1/NRP1/ABL1/MMP14/FERMT2/PTK2 6 GO:0090109 regulation of cell-substrate junction assembly 6/389 66/18722 0.00246141980680251 0.0690522925800673 LRP1/NRP1/ABL1/MMP14/FERMT2/PTK2 6 GO:1902476 chloride transmembrane transport 6/389 66/18722 0.00246141980680251 0.0690522925800673 GABRE/ANO2/SLC1A3/PCYOX1/SLC26A2/ANO6 6 GO:0048701 embryonic cranial skeleton morphogenesis 5/389 46/18722 0.00256956631580055 0.0715359416314856 GLI3/MMP14/FGFR2/SLC39A1/CHST11 5 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway 3/389 14/18722 0.00273229656679826 0.0754900422660094 PDGFRL/LRP1/ABL1 3 GO:0050885 neuromuscular process controlling balance 5/389 47/18722 0.00282729264293739 0.0775273403668621 SLC1A3/RAC3/ABL1/CLN3/RBFOX2 5 GO:0098661 inorganic anion transmembrane transport 7/389 91/18722 0.00287238286870347 0.0781759725534445 GABRE/ANO2/SLC1A3/PCYOX1/SLC26A2/SLC25A11/ANO6 7 GO:0031346 positive regulation of cell projection organization 16/389 353/18722 0.00306615791661288 0.0828316883102754 PROM2/COBL/CBFA2T2/LRP1/CDC42EP4/SCARB2/ITGA6/STK25/NRP1/PLXNB1/CDKL3/P3H1/TENM3/CYFIP1/RAPGEF2/EZH2 16 GO:0140058 neuron projection arborization 4/389 30/18722 0.00328007957472734 0.0879591927134604 LRP2/MYO9A/NRP1/TPBG 4 GO:0061351 neural precursor cell proliferation 9/389 145/18722 0.00334415783402201 0.0882402146115661 ASPM/LRP2/FZD3/GLI3/RACGAP1/FGFR2/SPINT1/PSMG1/ADGRG1 9 GO:0045732 positive regulation of protein catabolic process 12/389 231/18722 0.00336291921357886 0.0882402146115661 LRP2/GJA1/LRP1/HACE1/TMTC3/USP5/MAGEF1/FZR1/TRIB1/CEBPA/PTK2/RNF19B 12 GO:1905146 lysosomal protein catabolic process 3/389 15/18722 0.00336314500438928 0.0882402146115661 LRP2/LRP1/CLN3 3 GO:0051932 synaptic transmission, GABAergic 5/389 49/18722 0.0033980027778828 0.0885016257163923 GABRE/RAC3/TPBG/CLN3/EZH2 5 GO:0032956 regulation of actin cytoskeleton organization 16/389 357/18722 0.00342164223361977 0.0885016257163923 MET/EPHA1/TJP1/LRP1/WASF1/CDC42EP4/JAM3/RAC3/NRP1/ABL1/FERMT2/KANK4/TRIM27/CYFIP1/MYO1C/LIMA1 16 GO:0048813 dendrite morphogenesis 9/389 146/18722 0.00350034381404512 0.0898996752804406 DCDC2/EPHB3/LZTS1/BTBD3/NRP1/TPBG/RBFOX2/CDKL3/RAPGEF2 9 GO:0003018 vascular process in circulatory system 13/389 263/18722 0.0035470505966914 0.0901262257928735 LRP2/SLC1A3/GJA1/TJP1/LRP1/TFRC/DOCK5/FERMT2/TJP2/HMGCR/SLC16A1/SLC2A1/EGFR 13 GO:0150116 regulation of cell-substrate junction organization 6/389 71/18722 0.00355858966662292 0.0901262257928735 LRP1/NRP1/ABL1/MMP14/FERMT2/PTK2 6 GO:0051897 positive regulation of protein kinase B signaling 8/389 120/18722 0.00360248878268445 0.0902610064192108 MET/LRP2/GCNT2/TPBG/FERMT2/STK3/PTK2/EGFR 8 GO:0008593 regulation of Notch signaling pathway 7/389 95/18722 0.0036552066768507 0.0902610064192108 EGFL7/CBFA2T2/AAK1/YAP1/MMP14/GALNT11/IL6ST 7 GO:0030516 regulation of axon extension 7/389 95/18722 0.0036552066768507 0.0902610064192108 SEMA4G/SEMA6A/LRP1/NRP1/ABL1/CDKL3/CYFIP1 7 GO:0006301 postreplication repair 4/389 31/18722 0.00370515426561235 0.0902610064192108 USP43/POLI/PCNA/SPRTN 4 GO:0030201 heparan sulfate proteoglycan metabolic process 4/389 31/18722 0.00370515426561235 0.0902610064192108 GLCE/HS6ST2/EXTL2/GPC1 4 GO:0045814 negative regulation of gene expression, epigenetic 5/389 50/18722 0.00371240772220499 0.0902610064192108 DNMT3A/SUV39H1/TRIM27/EZH2/HELLS 5 GO:0051258 protein polymerization 14/389 296/18722 0.00374795699244592 0.0905218486851012 MET/ARL6/COBL/WASF1/CDC42EP4/ABL1/MIEF2/KANK4/TRIM27/ARL3/CLIP1/CYFIP1/FKBP4/MYO1C 14 GO:0044272 sulfur compound biosynthetic process 9/389 148/18722 0.0038298776577256 0.0918918672218768 SLC7A11/CHPF/MPST/PDK2/GLCE/SLC26A2/MTHFD2L/CHST11/CHST14 9 GO:0010769 regulation of cell morphogenesis involved in differentiation 7/389 96/18722 0.00387406135448478 0.0923444559464445 RAC3/NRP1/DOCK5/ABL1/FERMT2/CDKL3/PTK2 7 GO:0030324 lung development 10/389 177/18722 0.00399292306012264 0.0945596779238134 SLC7A11/ELK1/DAG1/GLI3/YAP1/MMP14/FGFR2/LAMA5/CEBPA/EGFR 10 GO:0021872 forebrain generation of neurons 5/389 51/18722 0.004047124062282 0.0946832636195856 ASPM/GLI3/NRP1/FGFR2/RAPGEF2 5 GO:0001845 phagolysosome assembly 3/389 16/18722 0.0040760275262613 0.0946832636195856 RAB7B/CLN3/TMEM175 3 GO:0072148 epithelial cell fate commitment 3/389 16/18722 0.0040760275262613 0.0946832636195856 NR2F2/NRP1/ESRP1 3 GO:0031334 positive regulation of protein-containing complex assembly 12/389 237/18722 0.00412868784785955 0.094960558769836 MET/UNC13B/WASF1/CDC42EP4/TFRC/FERMT2/TRIM27/ARL3/CLIP1/CYFIP1/MPP7/MYO1C 12 GO:0007435 salivary gland morphogenesis 4/389 32/18722 0.00416607880536709 0.094960558769836 DAG1/NRP1/FGFR2/LAMA5 4 GO:0021799 cerebral cortex radially oriented cell migration 4/389 32/18722 0.00416607880536709 0.094960558769836 MBOAT7/GLI3/FBXO45/ADGRG1 4 GO:0031103 axon regeneration 5/389 52/18722 0.00440285703224269 0.0997342832086278 DAG1/NREP/LRP1/LRIG2/JAM3 5 GO:0015698 inorganic anion transport 10/389 180/18722 0.00449368498447464 0.100542755450178 GABRE/ANO2/SLC1A3/CLDN4/PCYOX1/SLC22A11/RACGAP1/SLC26A2/SLC25A11/ANO6 10 GO:0048660 regulation of smooth muscle cell proliferation 10/389 180/18722 0.00449368498447464 0.100542755450178 NDRG2/ADAMTS1/PPARG/GJA1/FGFR2/HMGCR/TRIB1/IRAK4/EGFR/SKP2 10 GO:0051222 positive regulation of protein transport 14/389 303/18722 0.00460123705208204 0.102321411761849 UNC13B/FZD5/GJA1/WLS/CDH1/GLI3/LRP1/TMEM30B/CLN3/MIEF2/TCAF1/TM9SF4/MYO1C/EGFR 14 GO:0006024 glycosaminoglycan biosynthetic process 6/389 75/18722 0.00466954521529872 0.102624994603574 CHPF/GCNT2/GLCE/HS6ST2/CHST11/CHST14 6 GO:0030323 respiratory tube development 10/389 181/18722 0.00467116783772781 0.102624994603574 SLC7A11/ELK1/DAG1/GLI3/YAP1/MMP14/FGFR2/LAMA5/CEBPA/EGFR 10 GO:0008347 glial cell migration 5/389 53/18722 0.00478030806845549 0.104393913327288 MBOAT7/GLI3/LRP1/MMP14/ADGRG1 5 GO:0001780 neutrophil homeostasis 3/389 17/18722 0.00487393852812137 0.1051790166394 SLC7A11/JAM3/XKR8 3 GO:0061298 retina vasculature development in camera-type eye 3/389 17/18722 0.00487393852812137 0.1051790166394 COL4A1/LRP5/NRP1 3 GO:0001655 urogenital system development 15/389 338/18722 0.00494604415694025 0.105296492736352 LRP2/LGR5/EPHB3/PYGO1/COL4A1/ADAMTS1/MPST/GLI3/YAP1/NRP1/FGFR2/LAMA5/ARL3/AHI1/HELLS 15 GO:0008360 regulation of cell shape 9/389 154/18722 0.00496599856063956 0.105296492736352 BAMBI/DAG1/CDC42EP4/RAC3/FERMT2/EPB41L3/PLXNB1/CYFIP1/PTK2 9 GO:0050770 regulation of axonogenesis 9/389 154/18722 0.00496599856063956 0.105296492736352 EPHB3/SEMA4G/SEMA6A/LRP1/STK25/NRP1/PLXNB1/CDKL3/CYFIP1 9 GO:0016358 dendrite development 12/389 243/18722 0.005028629710179 0.106008165046375 DCDC2/EPHB3/LZTS1/COBL/BTBD3/NRP1/TPBG/RBFOX2/CDKL3/CYFIP1/RAPGEF2/EZH2 12 GO:0006790 sulfur compound metabolic process 15/389 339/18722 0.00507996451239942 0.106105175244564 SLC7A11/CHPF/MPST/SLC19A3/PDK2/BLMH/LYRM4/GLCE/SLC26A2/BTD/GSTA4/ACSF2/MTHFD2L/CHST11/CHST14 15 GO:0001706 endoderm formation 5/389 54/18722 0.0051801739231781 0.106105175244564 MMP15/COL4A2/MMP14/ITGB5/ITGAV 5 GO:2000179 positive regulation of neural precursor cell proliferation 5/389 54/18722 0.0051801739231781 0.106105175244564 ASPM/LRP2/FZD3/GLI3/ADGRG1 5 GO:0000096 sulfur amino acid metabolic process 4/389 34/18722 0.00520086290182814 0.106105175244564 SLC7A11/MPST/BLMH/MTHFD2L 4 GO:0006270 DNA replication initiation 4/389 34/18722 0.00520086290182814 0.106105175244564 MCM10/WRNIP1/POLA2/MCM5 4 GO:0007015 actin filament organization 18/389 441/18722 0.00523608816178715 0.106105175244564 MET/EPHA1/COBL/GAS2L3/TJP1/WASF1/CDC42EP4/RAC3/NRP1/ABL1/FERMT2/FAT1/ITGB5/KANK4/TRIM27/CYFIP1/MYO1C/LIMA1 18 GO:0048659 smooth muscle cell proliferation 10/389 184/18722 0.00523688827639744 0.106105175244564 NDRG2/ADAMTS1/PPARG/GJA1/FGFR2/HMGCR/TRIB1/IRAK4/EGFR/SKP2 10 GO:0007492 endoderm development 6/389 77/18722 0.00531195964654982 0.106548802326139 MMP15/COL4A2/MMP14/LAMC1/ITGB5/ITGAV 6 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 8/389 128/18722 0.00531721470341576 0.106548802326139 LTBP1/BAMBI/PBLD/SPRED2/PPARG/NREP/FBN2/CHST11 8 GO:0051896 regulation of protein kinase B signaling 10/389 185/18722 0.00543693551786629 0.108285956272052 MET/LRP2/DAG1/GCNT2/TPBG/FERMT2/OTUD3/STK3/PTK2/EGFR 10 GO:0110053 regulation of actin filament organization 13/389 277/18722 0.00546328926626202 0.108285956272052 MET/EPHA1/TJP1/WASF1/CDC42EP4/NRP1/ABL1/FERMT2/KANK4/TRIM27/CYFIP1/MYO1C/LIMA1 13 GO:0031113 regulation of microtubule polymerization 5/389 55/18722 0.00560314580397776 0.110457690524902 MET/ABL1/ARL3/CLIP1/FKBP4 5 GO:0031345 negative regulation of cell projection organization 10/389 186/18722 0.00564291321080945 0.110475228007996 SEMA4G/SEMA6A/CBFA2T2/LRP1/LRIG2/YAP1/NRP1/CDKL3/RAPGEF2/FKBP4 10 GO:0009612 response to mechanical stimulus 11/389 216/18722 0.00566461958801626 0.110475228007996 SLC1A3/GJA1/DAG1/MEIS2/MMP14/SERPINE2/ABHD12/DMD/PTK2/SLC2A1/EGFR 11 GO:0008272 sulfate transport 3/389 18/18722 0.00575957637159378 0.110894253168602 RACGAP1/SLC26A2/SLC25A11 3 GO:1900006 positive regulation of dendrite development 3/389 18/18722 0.00575957637159378 0.110894253168602 COBL/CYFIP1/EZH2 3 GO:0097421 liver regeneration 4/389 35/18722 0.00577732604936507 0.110894253168602 GLI3/PCNA/EZH2/EGFR 4 GO:0070374 positive regulation of ERK1 and ERK2 cascade 11/389 217/18722 0.005859500728247 0.111882718093805 LRP1/GCNT2/NRP1/TPBG/ABL1/FERMT2/FGFR2/HMGCR/RAPGEF2/EGFR/SHC1 11 GO:0048661 positive regulation of smooth muscle cell proliferation 7/389 104/18722 0.00600104155595386 0.112747055316336 ADAMTS1/GJA1/FGFR2/HMGCR/IRAK4/EGFR/SKP2 7 GO:0006023 aminoglycan biosynthetic process 6/389 79/18722 0.00601681469421125 0.112747055316336 CHPF/GCNT2/GLCE/HS6ST2/CHST11/CHST14 6 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 6/389 79/18722 0.00601681469421125 0.112747055316336 RAC3/NRP1/DOCK5/ABL1/FERMT2/CDKL3 6 GO:0016049 cell growth 19/389 482/18722 0.00602842769034425 0.112747055316336 ATAD3A/SEMA4G/SYT1/SEMA6A/COBL/GJA1/LRP1/DCBLD2/WASF1/DCUN1D3/NRP1/ABL1/MMP14/EPB41L3/CDKL3/SERPINE2/CYFIP1/TMEM97/EGFR 19 GO:0045926 negative regulation of growth 12/389 249/18722 0.00607862393280125 0.112924877881619 WWC1/SEMA4G/SEMA6A/GJA1/DCBLD2/DCUN1D3/NRP1/CDKL3/MT1A/SERPINE2/WWC3/STK3 12 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 8/389 131/18722 0.0060998631594952 0.112924877881619 LTBP1/BAMBI/PBLD/SPRED2/PPARG/NREP/FBN2/CHST11 8 GO:0001558 regulation of cell growth 17/389 414/18722 0.0061906282916951 0.114026370605111 ATAD3A/SEMA4G/SYT1/SEMA6A/GJA1/LRP1/DCBLD2/DCUN1D3/NRP1/ABL1/MMP14/EPB41L3/CDKL3/SERPINE2/CYFIP1/TMEM97/EGFR 17 GO:0009791 post-embryonic development 6/389 80/18722 0.00639370626528229 0.116416338606684 FZD5/ZFX/KDM5B/ABL1/FGFR2/CHST11 6 GO:0070306 lens fiber cell differentiation 4/389 36/18722 0.00639484256890025 0.116416338606684 SLC7A11/SPRED2/KDM5B/FZR1 4 GO:0032535 regulation of cellular component size 16/389 382/18722 0.00649278943651193 0.116416338606684 SEMA4G/PEX11A/SEMA6A/LRP1/WASF1/CDC42EP4/NRP1/ABL1/CLN3/CDKL3/KANK4/TRIM27/CYFIP1/MYO1C/LIMA1/ANO6 16 GO:1902903 regulation of supramolecular fiber organization 16/389 382/18722 0.00649278943651193 0.116416338606684 MET/EPHA1/TJP1/WASF1/CDC42EP4/NRP1/ABL1/FERMT2/KANK4/TRIM27/ARL3/CLIP1/CYFIP1/FKBP4/MYO1C/LIMA1 16 GO:0006766 vitamin metabolic process 7/389 106/18722 0.0066475102807035 0.116416338606684 LRP2/SLC19A3/BTD/SHMT1/MMAB/MTHFD2L/SLC2A1 7 GO:0030038 contractile actin filament bundle assembly 7/389 106/18722 0.0066475102807035 0.116416338606684 MET/EPHA1/TJP1/NRP1/ABL1/FERMT2/ITGB5 7 GO:0043149 stress fiber assembly 7/389 106/18722 0.0066475102807035 0.116416338606684 MET/EPHA1/TJP1/NRP1/ABL1/FERMT2/ITGB5 7 GO:0090263 positive regulation of canonical Wnt signaling pathway 7/389 106/18722 0.0066475102807035 0.116416338606684 ASPM/LGR5/BAMBI/WLS/YAP1/FGFR2/EGFR 7 GO:1905477 positive regulation of protein localization to membrane 7/389 106/18722 0.0066475102807035 0.116416338606684 PRKCH/LRP1/CLN3/MIEF2/TCAF1/MYO1C/EGFR 7 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 8/389 133/18722 0.00666827557119626 0.116416338606684 TMTC3/USP5/MAGEF1/FZR1/TRIB1/CEBPA/PTK2/RNF19B 8 GO:0006520 cellular amino acid metabolic process 13/389 284/18722 0.00669231825271272 0.116416338606684 SLC7A11/SLC1A3/TARS2/MPST/BCKDHB/BLMH/ENOSF1/SEPHS1/CLN3/GLDC/HARS2/SHMT1/MTHFD2L 13 GO:0006743 ubiquinone metabolic process 3/389 19/18722 0.00673535712805329 0.116416338606684 AIFM2/HMGCR/COQ9 3 GO:0007039 protein catabolic process in the vacuole 3/389 19/18722 0.00673535712805329 0.116416338606684 LRP2/LRP1/CLN3 3 GO:0021954 central nervous system neuron development 6/389 81/18722 0.00678746448556969 0.116763598956946 EPHB3/FBXO45/RAC3/NRP1/FGFR2/RAPGEF2 6 GO:0060828 regulation of canonical Wnt signaling pathway 12/389 253/18722 0.00687015912772375 0.117631316144641 ASPM/LGR5/BAMBI/WLS/GLI3/YAP1/TPBG/TMEM170B/CTNND1/FGFR2/STK3/EGFR 12 GO:0031532 actin cytoskeleton reorganization 7/389 107/18722 0.00698950171079774 0.11793942851787 TJP1/NRP1/CLDN3/ABL1/NRK/THSD7A/SHC1 7 GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 7/389 107/18722 0.00698950171079774 0.11793942851787 USP5/MAGEF1/FZR1/TRIB1/CEBPA/PTK2/RNF19B 7 GO:0001954 positive regulation of cell-matrix adhesion 5/389 58/18722 0.00701750918244522 0.11793942851787 EPHA1/DAG1/NRP1/ABL1/FERMT2 5 GO:0007405 neuroblast proliferation 5/389 58/18722 0.00701750918244522 0.11793942851787 ASPM/FZD3/GLI3/RACGAP1/FGFR2 5 GO:0097484 dendrite extension 4/389 37/18722 0.00705461720760963 0.118019215395194 SYT1/WASF1/CDKL3/CYFIP1 4 GO:1904951 positive regulation of establishment of protein localization 14/389 319/18722 0.00714807229129535 0.119036619389745 UNC13B/FZD5/GJA1/WLS/CDH1/GLI3/LRP1/TMEM30B/CLN3/MIEF2/TCAF1/TM9SF4/MYO1C/EGFR 14 GO:0001892 embryonic placenta development 6/389 82/18722 0.00719850540306244 0.119331587295312 FZD5/NR2F2/FGFR2/CEBPA/SPINT1/STK3 6 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 12/389 256/18722 0.00751546563228547 0.12402218624862 LRP2/LTBP1/BAMBI/PBLD/SPRED2/PPARG/ACVR2A/NREP/LRP1/FBN2/ABL1/CHST11 12 GO:0003158 endothelium development 8/389 136/18722 0.00759493078861689 0.124542714182328 MET/NR2F2/GJA1/TJP1/NRP1/CLDN3/TJP2/RAPGEF2 8 GO:0010001 glial cell differentiation 11/389 225/18722 0.00761530717374807 0.124542714182328 ITGB4/DAG1/GLI3/LRP1/ABL1/SERPINE2/ERBB3/SPINT1/IL6ST/EGFR/GPC1 11 GO:0006821 chloride transport 7/389 109/18722 0.00771241102622857 0.125567692020784 GABRE/ANO2/SLC1A3/CLDN4/PCYOX1/SLC26A2/ANO6 7 GO:0017121 plasma membrane phospholipid scrambling 3/389 20/18722 0.00780342782512707 0.126484894569949 PLSCR4/XKR8/ANO6 3 GO:0010977 negative regulation of neuron projection development 8/389 137/18722 0.00792437663043407 0.127876998102624 SEMA4G/SEMA6A/CBFA2T2/LRP1/LRIG2/NRP1/CDKL3/FKBP4 8 GO:0040013 negative regulation of locomotion 16/389 391/18722 0.00803339206051152 0.128078798510308 SRGAP3/EPHA1/SEMA4G/MARVELD3/SEMA6A/PPARG/NR2F2/GJA1/DAG1/CDH1/LRP1/NRP1/CLDN3/TRIB1/TCAF1/ADGRG1 16 GO:0006835 dicarboxylic acid transport 6/389 84/18722 0.00807408945434797 0.128078798510308 LRP2/SLC7A11/SLC1A3/GJA1/SLC26A2/SLC25A11 6 GO:0031102 neuron projection regeneration 5/389 60/18722 0.0080882969342616 0.128078798510308 DAG1/NREP/LRP1/LRIG2/JAM3 5 GO:0061387 regulation of extent of cell growth 7/389 110/18722 0.00809389323794594 0.128078798510308 SEMA4G/SEMA6A/LRP1/NRP1/ABL1/CDKL3/CYFIP1 7 GO:0046777 protein autophosphorylation 11/389 227/18722 0.00811247668107516 0.128078798510308 EPHB3/EPHA1/EPHB4/AAK1/STK25/TRIM24/ABL1/FGFR2/SIK2/PTK2/EGFR 11 GO:0032273 positive regulation of protein polymerization 8/389 138/18722 0.008264444426344 0.129915641477916 MET/WASF1/CDC42EP4/TRIM27/ARL3/CLIP1/CYFIP1/MYO1C 8 GO:0071900 regulation of protein serine/threonine kinase activity 15/389 359/18722 0.00843627698345568 0.131963505494552 FZD5/PPARG/LRP5/NR2F2/HGS/ABL1/FERMT2/HMGCR/TRIB1/BLM/CEBPA/RAPGEF2/EZH2/STK3/EGFR 15 GO:0090288 negative regulation of cellular response to growth factor stimulus 7/389 111/18722 0.00848910263508678 0.131963505494552 LRP2/BAMBI/SEMA6A/PPARG/HGS/ABL1/GPC1 7 GO:0046621 negative regulation of organ growth 4/389 39/18722 0.00850555125944652 0.131963505494552 WWC1/GJA1/WWC3/STK3 4 GO:0032092 positive regulation of protein binding 6/389 85/18722 0.00853945360480238 0.131963505494552 BAMBI/LRP1/NRP1/ABL1/RAPGEF2/STK3 6 GO:0045598 regulation of fat cell differentiation 8/389 139/18722 0.00861533933728889 0.132097392025521 CDS1/PPARG/LRP5/YAP1/FERMT2/CEBPA/STK3/XBP1 8 GO:0031099 regeneration 10/389 198/18722 0.00862055917249081 0.132097392025521 DAG1/GLI3/NREP/LRP1/LRIG2/JAM3/YAP1/PCNA/EZH2/EGFR 10 GO:0032288 myelin assembly 3/389 21/18722 0.00896567921164566 0.136318154771743 ITGB4/EPB41L3/GPC1 3 GO:0030177 positive regulation of Wnt signaling pathway 8/389 140/18722 0.00897726653634732 0.136318154771743 ASPM/LGR5/BAMBI/WLS/YAP1/ABL1/FGFR2/EGFR 8 GO:0032970 regulation of actin filament-based process 16/389 396/18722 0.00900813690704416 0.136318154771743 MET/EPHA1/TJP1/LRP1/WASF1/CDC42EP4/JAM3/RAC3/NRP1/ABL1/FERMT2/KANK4/TRIM27/CYFIP1/MYO1C/LIMA1 16 GO:0043588 skin development 12/389 263/18722 0.00920662770935565 0.138746162214959 MET/ITGB4/LGR5/PRKCH/CLDN4/FZD3/ITGA6/YAP1/FGFR2/LSR/LAMA5/EGFR 12 GO:0014037 Schwann cell differentiation 4/389 40/18722 0.00929890811446737 0.139543258283955 ITGB4/DAG1/ERBB3/GPC1 4 GO:0006869 lipid transport 16/389 398/18722 0.00942348805400575 0.139543258283955 SLC27A2/PPARG/LRP1/TMEM30B/SCARB2/KDM5B/CLN3/SIGMAR1/SLC27A6/PLSCR4/SERAC1/XKR8/ITGAV/SLC2A1/LIMA1/ANO6 16 GO:0032271 regulation of protein polymerization 11/389 232/18722 0.00946594064462693 0.139543258283955 MET/WASF1/CDC42EP4/ABL1/KANK4/TRIM27/ARL3/CLIP1/CYFIP1/FKBP4/MYO1C 11 GO:0048638 regulation of developmental growth 14/389 330/18722 0.00947370111247763 0.139543258283955 WWC1/SEMA4G/SYT1/SEMA6A/GJA1/LRP1/YAP1/NRP1/ABL1/FGFR2/CDKL3/WWC3/CYFIP1/STK3 14 GO:0048041 focal adhesion assembly 6/389 87/18722 0.00952735709150116 0.139543258283955 LRP1/NRP1/ABL1/MMP14/FERMT2/PTK2 6 GO:0150104 transport across blood-brain barrier 6/389 87/18722 0.00952735709150116 0.139543258283955 LRP2/SLC1A3/LRP1/TFRC/SLC16A1/SLC2A1 6 GO:2000177 regulation of neural precursor cell proliferation 6/389 87/18722 0.00952735709150116 0.139543258283955 ASPM/LRP2/FZD3/GLI3/SPINT1/ADGRG1 6 GO:0022617 extracellular matrix disassembly 5/389 63/18722 0.00989921775331817 0.144409788585405 MMP15/CTSV/LRP1/MMP14/LAMC1 5 GO:0007219 Notch signaling pathway 9/389 172/18722 0.00998063047107344 0.144441902095257 EGFL7/CBFA2T2/AAK1/YAP1/MMP14/GALNT11/CEBPA/DTX4/IL6ST 9 GO:1990138 neuron projection extension 9/389 172/18722 0.00998063047107344 0.144441902095257 SEMA4G/SYT1/SEMA6A/LRP1/WASF1/NRP1/ABL1/CDKL3/CYFIP1 9 GO:0060541 respiratory system development 10/389 203/18722 0.0101679161543061 0.146219786790404 SLC7A11/ELK1/DAG1/GLI3/YAP1/MMP14/FGFR2/LAMA5/CEBPA/EGFR 10 GO:0060343 trabecula formation 3/389 22/18722 0.0102237580563622 0.146219786790404 ADAMTS1/FBN2/FHL2 3 GO:0060713 labyrinthine layer morphogenesis 3/389 22/18722 0.0102237580563622 0.146219786790404 FZD5/FGFR2/SPINT1 3 GO:0045785 positive regulation of cell adhesion 17/389 437/18722 0.0102975288376877 0.146699561215027 CCDC80/EPHA1/DAG1/TJP1/GLI3/RAC3/TFRC/GCNT2/ITGA6/NRP1/DOCK5/ABL1/FERMT2/ITGAV/IL6ST/ADGRG1/XBP1 17 GO:0046718 viral entry into host cell 8/389 144/18722 0.0105393967202896 0.149177260575952 DAG1/SCARB2/TFRC/NRP1/ITGB5/TRIM27/ITGAV/EGFR 8 GO:0001885 endothelial cell development 5/389 64/18722 0.0105599423295056 0.149177260575952 MET/TJP1/CLDN3/TJP2/RAPGEF2 5 GO:0014910 regulation of smooth muscle cell migration 6/389 89/18722 0.0105941624593286 0.149177260575952 PLAU/ADAMTS1/LRP1/NRP1/DOCK5/TRIB1 6 GO:0048762 mesenchymal cell differentiation 11/389 236/18722 0.0106690513531987 0.149653962635061 BAMBI/SEMA4G/SPRED2/SEMA6A/DAG1/GCNT2/NRP1/FERMT2/FGFR2/LAMA5/EZH2 11 GO:0007584 response to nutrient 9/389 174/18722 0.0107131986387994 0.149697453776633 PPARG/DNMT3A/BCKDHB/PDK2/TRIM24/HMGCR/SLC16A1/EGFR/XBP1 9 GO:0072001 renal system development 13/389 302/18722 0.0108746599111498 0.151373605709784 LRP2/LGR5/PYGO1/COL4A1/ADAMTS1/MPST/GLI3/YAP1/NRP1/FGFR2/LAMA5/ARL3/AHI1 13 GO:0021795 cerebral cortex cell migration 4/389 42/18722 0.0110265617142123 0.151750454987669 MBOAT7/GLI3/FBXO45/ADGRG1 4 GO:0045687 positive regulation of glial cell differentiation 4/389 42/18722 0.0110265617142123 0.151750454987669 DAG1/SERPINE2/SPINT1/IL6ST 4 GO:2001222 regulation of neuron migration 4/389 42/18722 0.0110265617142123 0.151750454987669 SEMA6A/LRIG2/RAPGEF2/ADGRG1 4 GO:0015849 organic acid transport 13/389 303/18722 0.011155882315177 0.152953018058084 LRP2/SLC7A11/SLC1A3/SLC27A2/PPARG/GJA1/SLC38A9/CLN3/SLC27A6/SLC26A2/SLC25A11/SLC16A1/SLC2A1 13 GO:0002052 positive regulation of neuroblast proliferation 3/389 23/18722 0.0115790789953116 0.155810913519678 ASPM/FZD3/GLI3 3 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 3/389 23/18722 0.0115790789953116 0.155810913519678 LRP1/HGS/LRIG2 3 GO:0021884 forebrain neuron development 3/389 23/18722 0.0115790789953116 0.155810913519678 NRP1/FGFR2/RAPGEF2 3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process 3/389 23/18722 0.0115790789953116 0.155810913519678 CYTL1/CHPF/CHST11 3 GO:0060575 intestinal epithelial cell differentiation 3/389 23/18722 0.0115790789953116 0.155810913519678 CBFA2T2/YAP1/IL6ST 3 GO:0030203 glycosaminoglycan metabolic process 7/389 118/18722 0.0116633889198991 0.155810913519678 CHPF/GCNT2/GLCE/HS6ST2/ITIH5/CHST11/CHST14 7 GO:0045446 endothelial cell differentiation 7/389 118/18722 0.0116633889198991 0.155810913519678 MET/NR2F2/TJP1/NRP1/CLDN3/TJP2/RAPGEF2 7 GO:0051492 regulation of stress fiber assembly 6/389 91/18722 0.0117430162805742 0.156302118157862 MET/EPHA1/TJP1/NRP1/ABL1/FERMT2 6 GO:0016331 morphogenesis of embryonic epithelium 8/389 147/18722 0.0118368536959927 0.156978201561038 LRP2/COBL/FZD3/ABL1/FGFR2/LAMA5/SPINT1/STK3 8 GO:0030517 negative regulation of axon extension 4/389 43/18722 0.0119627859572787 0.157502817278684 SEMA4G/SEMA6A/NRP1/CDKL3 4 GO:0061383 trabecula morphogenesis 4/389 43/18722 0.0119627859572787 0.157502817278684 ADAMTS1/FBN2/PLXNB1/FHL2 4 GO:0048675 axon extension 7/389 120/18722 0.0127096853833942 0.1662938921699 SEMA4G/SEMA6A/LRP1/NRP1/ABL1/CDKL3/CYFIP1 7 GO:0009880 embryonic pattern specification 5/389 67/18722 0.0127216879395125 0.1662938921699 FZD5/COBL/MEIS2/NRP1/FGFR2 5 GO:0010876 lipid localization 17/389 448/18722 0.0129101506609151 0.166698272188343 CDS1/SLC27A2/PPARG/LRP1/TMEM30B/SCARB2/KDM5B/CLN3/SIGMAR1/SLC27A6/PLSCR4/SERAC1/XKR8/ITGAV/SLC2A1/LIMA1/ANO6 17 GO:0003148 outflow tract septum morphogenesis 3/389 24/18722 0.0130328359422441 0.166698272188343 LRP2/NRP1/FGFR2 3 GO:0021801 cerebral cortex radial glia-guided migration 3/389 24/18722 0.0130328359422441 0.166698272188343 MBOAT7/GLI3/ADGRG1 3 GO:0022030 telencephalon glial cell migration 3/389 24/18722 0.0130328359422441 0.166698272188343 MBOAT7/GLI3/ADGRG1 3 GO:0030859 polarized epithelial cell differentiation 3/389 24/18722 0.0130328359422441 0.166698272188343 MYO9A/FAT1/AHI1 3 GO:0043491 protein kinase B signaling 10/389 211/18722 0.0130725818058311 0.166698272188343 MET/LRP2/DAG1/GCNT2/TPBG/FERMT2/OTUD3/STK3/PTK2/EGFR 10 GO:0046474 glycerophospholipid biosynthetic process 10/389 211/18722 0.0130725818058311 0.166698272188343 SYNJ2/TTC7B/SLC44A5/AGPAT4/CDS1/MBOAT7/SLC44A2/PIGV/CLN3/INPP4A 10 GO:0043409 negative regulation of MAPK cascade 9/389 180/18722 0.0131539141029492 0.167150957259428 C3orf33/NDRG2/SPRED2/MARVELD3/SEMA6A/PPARG/DAG1/ABL1/HMGCR 9 GO:1904888 cranial skeletal system development 5/389 68/18722 0.0135040186841326 0.17019551973612 GLI3/MMP14/FGFR2/SLC39A1/CHST11 5 GO:0008361 regulation of cell size 9/389 181/18722 0.0135977787331062 0.17019551973612 SEMA4G/SEMA6A/LRP1/NRP1/ABL1/CLN3/CDKL3/CYFIP1/ANO6 9 GO:0001738 morphogenesis of a polarized epithelium 6/389 94/18722 0.0136268417227713 0.17019551973612 MYO9A/FZD3/ABL1/FAT1/LAMA5/AHI1 6 GO:0061326 renal tubule development 6/389 94/18722 0.0136268417227713 0.17019551973612 LGR5/COL4A1/GLI3/YAP1/LAMA5/AHI1 6 GO:1903035 negative regulation of response to wounding 6/389 94/18722 0.0136268417227713 0.17019551973612 PLAU/GJA1/LRIG2/CLDN3/HMGCR/SERPINE2 6 GO:0044409 entry into host 8/389 151/18722 0.0137449999680054 0.171085375028381 DAG1/SCARB2/TFRC/NRP1/ITGB5/TRIM27/ITGAV/EGFR 8 GO:0048546 digestive tract morphogenesis 4/389 45/18722 0.0139844996413523 0.173474388408203 EPHB3/GLI3/FGFR2/AHI1 4 GO:0015012 heparan sulfate proteoglycan biosynthetic process 3/389 25/18722 0.0145860130761464 0.177317298962353 GLCE/HS6ST2/EXTL2 3 GO:0060706 cell differentiation involved in embryonic placenta development 3/389 25/18722 0.0145860130761464 0.177317298962353 FZD5/NR2F2/STK3 3 GO:0061436 establishment of skin barrier 3/389 25/18722 0.0145860130761464 0.177317298962353 MET/CLDN4/LSR 3 GO:0090382 phagosome maturation 3/389 25/18722 0.0145860130761464 0.177317298962353 RAB7B/CLN3/TMEM175 3 GO:1904754 positive regulation of vascular associated smooth muscle cell migration 3/389 25/18722 0.0145860130761464 0.177317298962353 ADAMTS1/LRP1/DOCK5 3 GO:1905048 regulation of metallopeptidase activity 3/389 25/18722 0.0145860130761464 0.177317298962353 CLDN4/LRP1/CLDN3 3 GO:0033002 muscle cell proliferation 11/389 248/18722 0.0149885566789514 0.181605535575202 NDRG2/ADAMTS1/PPARG/GJA1/YAP1/FGFR2/HMGCR/TRIB1/IRAK4/EGFR/SKP2 11 GO:0061028 establishment of endothelial barrier 4/389 46/18722 0.0150716361485476 0.1820074736217 TJP1/CLDN3/TJP2/RAPGEF2 4 GO:0014909 smooth muscle cell migration 6/389 97/18722 0.0157122007749276 0.188540784432409 PLAU/ADAMTS1/LRP1/NRP1/DOCK5/TRIB1 6 GO:0009101 glycoprotein biosynthetic process 13/389 317/18722 0.0157160401610783 0.188540784432409 UGGT2/CYTL1/CHPF/PMM1/GCNT2/TMTC2/TMTC3/GLCE/GALNT11/HS6ST2/EXTL2/CHST11/CHST14 13 GO:0034614 cellular response to reactive oxygen species 8/389 155/18722 0.0158684881344032 0.189217492315415 MET/PDK2/STK25/ABL1/SIGMAR1/PCNA/EZH2/EGFR 8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 9/389 186/18722 0.0159852902040157 0.189217492315415 ZDHHC13/GJA1/WLS/SLC44A2/TFRC/ABL1/TRIM27/ANKRD17/IRAK4 9 GO:0007163 establishment or maintenance of cell polarity 10/389 218/18722 0.0160908020513574 0.189217492315415 WWC1/DST/MYO9A/GJA1/JAM3/RAC3/STK25/FAT1/MPP7/PTK2 10 GO:0014911 positive regulation of smooth muscle cell migration 4/389 47/18722 0.0162106448467439 0.189217492315415 ADAMTS1/LRP1/NRP1/DOCK5 4 GO:0045332 phospholipid translocation 4/389 47/18722 0.0162106448467439 0.189217492315415 TMEM30B/PLSCR4/XKR8/ANO6 4 GO:0048668 collateral sprouting 3/389 26/18722 0.0162393954194475 0.189217492315415 COBL/LRP1/ABL1 3 GO:0048843 negative regulation of axon extension involved in axon guidance 3/389 26/18722 0.0162393954194475 0.189217492315415 SEMA4G/SEMA6A/NRP1 3 GO:0060669 embryonic placenta morphogenesis 3/389 26/18722 0.0162393954194475 0.189217492315415 FZD5/FGFR2/SPINT1 3 GO:0070102 interleukin-6-mediated signaling pathway 3/389 26/18722 0.0162393954194475 0.189217492315415 YAP1/CEBPA/IL6ST 3 GO:0070301 cellular response to hydrogen peroxide 6/389 98/18722 0.016453771267999 0.19110478921781 MET/STK25/ABL1/SIGMAR1/PCNA/EZH2 6 GO:0051017 actin filament bundle assembly 8/389 157/18722 0.017014889171296 0.192905577957835 MET/EPHA1/TJP1/NRP1/ABL1/FERMT2/ITGB5/LIMA1 8 GO:0002064 epithelial cell development 10/389 220/18722 0.0170411682756162 0.192905577957835 MET/TJP1/TFCP2L1/YAP1/CLDN3/TJP2/ADAMTSL4/FAT1/RAPGEF2/IL6ST 10 GO:0008654 phospholipid biosynthetic process 11/389 253/18722 0.0171330979162903 0.192905577957835 SYNJ2/TTC7B/SLC44A5/AGPAT4/CDS1/MBOAT7/SLC44A2/PIGV/CLN3/SERAC1/INPP4A 11 GO:0010717 regulation of epithelial to mesenchymal transition 6/389 99/18722 0.0172191409388153 0.192905577957835 BAMBI/SPRED2/DAG1/GCNT2/FERMT2/EZH2 6 GO:0043254 regulation of protein-containing complex assembly 16/389 427/18722 0.0173342896556767 0.192905577957835 MET/UNC13B/WASF1/CDC42EP4/JAM3/TFRC/ABL1/FERMT2/KANK4/TRIM27/ARL3/CLIP1/CYFIP1/MPP7/FKBP4/MYO1C 16 GO:0048568 embryonic organ development 16/389 427/18722 0.0173342896556767 0.192905577957835 FZD5/COBL/NR2F2/TEAD1/FZD3/GLI3/YAP1/FBN2/MMP14/FGFR2/CEBPA/AHI1/SPINT1/STK3/SLC39A1/CHST11 16 GO:0000098 sulfur amino acid catabolic process 2/389 10/18722 0.0173535198418905 0.192905577957835 MPST/BLMH 2 GO:0035999 tetrahydrofolate interconversion 2/389 10/18722 0.0173535198418905 0.192905577957835 SHMT1/MTHFD2L 2 GO:0036363 transforming growth factor beta activation 2/389 10/18722 0.0173535198418905 0.192905577957835 LTBP1/ITGAV 2 GO:0071838 cell proliferation in bone marrow 2/389 10/18722 0.0173535198418905 0.192905577957835 FGFR2/SETD4 2 GO:0098885 modification of postsynaptic actin cytoskeleton 2/389 10/18722 0.0173535198418905 0.192905577957835 WASF1/CYFIP1 2 GO:0140059 dendrite arborization 2/389 10/18722 0.0173535198418905 0.192905577957835 NRP1/TPBG 2 GO:1904350 regulation of protein catabolic process in the vacuole 2/389 10/18722 0.0173535198418905 0.192905577957835 LRP2/LRP1 2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation 2/389 10/18722 0.0173535198418905 0.192905577957835 WASF1/CYFIP1 2 GO:0033628 regulation of cell adhesion mediated by integrin 4/389 48/18722 0.0174022306411099 0.192905577957835 PLAU/JAM3/RAC3/PTK2 4 GO:0043010 camera-type eye development 13/389 322/18722 0.0176495749481209 0.19505454495696 SLC7A11/COL4A1/SPRED2/FZD5/LRP5/GLI3/NRP1/FBN2/KDM5B/FAT1/FZR1/TENM3/AHI1 13 GO:0018126 protein hydroxylation 3/389 27/18722 0.0179935790201105 0.197114786325604 P3H2/PLOD1/P3H1 3 GO:0033561 regulation of water loss via skin 3/389 27/18722 0.0179935790201105 0.197114786325604 MET/CLDN4/LSR 3 GO:0110020 regulation of actomyosin structure organization 6/389 100/18722 0.0180086439308677 0.197114786325604 MET/EPHA1/TJP1/NRP1/ABL1/FERMT2 6 GO:1903362 regulation of cellular protein catabolic process 11/389 255/18722 0.0180521904668911 0.197114786325604 LRP2/RHBDF1/LRP1/TMTC3/USP5/MAGEF1/FZR1/TRIB1/CEBPA/PTK2/RNF19B 11 GO:0006022 aminoglycan metabolic process 7/389 129/18722 0.0182636569402628 0.198828527943696 CHPF/GCNT2/GLCE/HS6ST2/ITIH5/CHST11/CHST14 7 GO:0033674 positive regulation of kinase activity 17/389 467/18722 0.0186231338671116 0.201797610137455 MET/EPHB3/CENPE/EPHA1/FZD5/EPHB4/DAG1/ABL1/FERMT2/FGFR2/RAPGEF2/ERBB3/EZH2/STK3/PRLR/PTK2/EGFR 17 GO:0034332 adherens junction organization 4/389 49/18722 0.018647050895619 0.201797610137455 TJP1/CDH1/JAM3/FERMT2 4 GO:0090316 positive regulation of intracellular protein transport 8/389 160/18722 0.0188445942353633 0.203332056734823 FZD5/CDH1/GLI3/TMEM30B/MIEF2/TCAF1/TM9SF4/MYO1C 8 GO:0060485 mesenchyme development 12/389 291/18722 0.0190889163136496 0.205360701462773 BAMBI/SEMA4G/SPRED2/SEMA6A/DAG1/GCNT2/YAP1/NRP1/FERMT2/FGFR2/LAMA5/EZH2 12 GO:0061572 actin filament bundle organization 8/389 161/18722 0.019484600715362 0.209000996496839 MET/EPHA1/TJP1/NRP1/ABL1/FERMT2/ITGB5/LIMA1 8 GO:0001841 neural tube formation 6/389 102/18722 0.0196613509452647 0.21027843664921 LRP2/COBL/FZD3/ABL1/SPINT1/STK3 6 GO:0051894 positive regulation of focal adhesion assembly 3/389 28/18722 0.0198489807504182 0.211574093694594 NRP1/ABL1/FERMT2 3 GO:0061333 renal tubule morphogenesis 5/389 75/18722 0.019898523207361 0.211574093694594 LGR5/COL4A1/GLI3/LAMA5/AHI1 5 GO:0072175 epithelial tube formation 7/389 132/18722 0.020443725939312 0.215213076696133 LRP2/COBL/FZD3/ABL1/FGFR2/SPINT1/STK3 7 GO:0006260 DNA replication 11/389 260/18722 0.0205100955559647 0.215213076696133 MCM10/POLI/WRNIP1/PCNA/POLA2/BLM/ANKRD17/E4F1/NFIC/MCM5/EGFR 11 GO:0050773 regulation of dendrite development 6/389 103/18722 0.0205251871199135 0.215213076696133 LZTS1/COBL/CDKL3/CYFIP1/RAPGEF2/EZH2 6 GO:0007389 pattern specification process 16/389 436/18722 0.0206177369396693 0.215213076696133 LRP2/FZD5/ARL6/LRP5/ACVR2A/COBL/NR2F2/WLS/GLI3/MEIS2/NRP1/FGFR2/GALNT11/AHI1/BHLHE41/ADGRG1 16 GO:0019048 modulation by virus of host process 2/389 11/18722 0.0209215757720743 0.215213076696133 DAG1/ANO6 2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway 2/389 11/18722 0.0209215757720743 0.215213076696133 YAP1/SKP2 2 GO:0035581 sequestering of extracellular ligand from receptor 2/389 11/18722 0.0209215757720743 0.215213076696133 LTBP1/FBN2 2 GO:0043589 skin morphogenesis 2/389 11/18722 0.0209215757720743 0.215213076696133 ITGB4/ITGA6 2 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway 2/389 11/18722 0.0209215757720743 0.215213076696133 WASF1/CYFIP1 2 GO:0060174 limb bud formation 2/389 11/18722 0.0209215757720743 0.215213076696133 ZNF219/FGFR2 2 GO:1905050 positive regulation of metallopeptidase activity 2/389 11/18722 0.0209215757720743 0.215213076696133 CLDN4/CLDN3 2 GO:0008652 cellular amino acid biosynthetic process 5/389 76/18722 0.0209489010768104 0.215213076696133 SLC1A3/SEPHS1/CLN3/SHMT1/MTHFD2L 5 GO:0048013 ephrin receptor signaling pathway 4/389 51/18722 0.0212987871327653 0.218192912003357 EPHB3/EPHA1/EPHB4/PTK2 4 GO:1901890 positive regulation of cell junction assembly 6/389 104/18722 0.0214144205217886 0.218763001801017 EPHB3/NRP1/TPBG/CLDN3/ABL1/FERMT2 6 GO:0001667 ameboidal-type cell migration 17/389 475/18722 0.0215428512686806 0.219079687848812 MET/ITGB4/SEMA4G/MARVELD3/SEMA6A/EPHB4/PPARG/LRP5/NR2F2/GJA1/NRP1/TPBG/DOCK5/ABL1/CLN3/LAMA5/PTK2 17 GO:0003002 regionalization 13/389 331/18722 0.021577017669668 0.219079687848812 LRP2/FZD5/LRP5/ACVR2A/COBL/NR2F2/WLS/GLI3/NRP1/FGFR2/AHI1/BHLHE41/ADGRG1 13 GO:0031032 actomyosin structure organization 9/389 196/18722 0.0216615528708986 0.219079687848812 MET/EPHA1/TJP1/NRP1/ABL1/FERMT2/RACGAP1/EPB41L3/ITGB5 9 GO:0006656 phosphatidylcholine biosynthetic process 3/389 29/18722 0.0218058477348831 0.219079687848812 SLC44A5/CDS1/SLC44A2 3 GO:0021591 ventricular system development 3/389 29/18722 0.0218058477348831 0.219079687848812 SLC7A11/MBOAT7/RAPGEF2 3 GO:0060441 epithelial tube branching involved in lung morphogenesis 3/389 29/18722 0.0218058477348831 0.219079687848812 DAG1/YAP1/FGFR2 3 GO:0071692 protein localization to extracellular region 14/389 368/18722 0.0223271716988253 0.222500360722499 LTBP1/UNC13B/RHBDF1/LRP5/GJA1/WLS/LRP1/FBN2/RAB11FIP3/HMGCR/P3H1/SLC16A1/CAMK2G/EGFR 14 GO:0032231 regulation of actin filament bundle assembly 6/389 105/18722 0.022329347963925 0.222500360722499 MET/EPHA1/TJP1/NRP1/ABL1/FERMT2 6 GO:0040029 regulation of gene expression, epigenetic 6/389 105/18722 0.022329347963925 0.222500360722499 DNMT3A/SUV39H1/TRIM27/TDG/EZH2/HELLS 6 GO:1990778 protein localization to cell periphery 13/389 333/18722 0.022532046927548 0.222611912445105 PRKCH/TTC7B/DAG1/CDH1/LRP1/TPBG/MMP14/CLN3/EPB41L3/LAMA5/ARL3/RAPGEF2/EGFR 13 GO:0010718 positive regulation of epithelial to mesenchymal transition 4/389 52/18722 0.0227067813078089 0.222611912445105 BAMBI/GCNT2/FERMT2/EZH2 4 GO:0021545 cranial nerve development 4/389 52/18722 0.0227067813078089 0.222611912445105 SLC1A3/GLI3/NRP1/ERBB3 4 GO:0030514 negative regulation of BMP signaling pathway 4/389 52/18722 0.0227067813078089 0.222611912445105 LRP2/BAMBI/PPARG/ABL1 4 GO:0034204 lipid translocation 4/389 52/18722 0.0227067813078089 0.222611912445105 TMEM30B/PLSCR4/XKR8/ANO6 4 GO:0051496 positive regulation of stress fiber assembly 4/389 52/18722 0.0227067813078089 0.222611912445105 EPHA1/NRP1/ABL1/FERMT2 4 GO:0008306 associative learning 5/389 78/18722 0.023156609901269 0.225205750159808 SLC7A11/MEIS2/TPBG/CLN3/HMGCR 5 GO:0061045 negative regulation of wound healing 5/389 78/18722 0.023156609901269 0.225205750159808 PLAU/GJA1/CLDN3/HMGCR/SERPINE2 5 GO:0070373 negative regulation of ERK1 and ERK2 cascade 5/389 78/18722 0.023156609901269 0.225205750159808 C3orf33/NDRG2/SPRED2/SEMA6A/ABL1 5 GO:0046620 regulation of organ growth 6/389 106/18722 0.0232702582249183 0.22570912698478 WWC1/GJA1/YAP1/FGFR2/WWC3/STK3 6 GO:1900180 regulation of protein localization to nucleus 7/389 136/18722 0.0236239371132606 0.22843301740512 POLR1A/CDH1/GLI3/TFRC/YAP1/FERMT2/NUP58 7 GO:0001654 eye development 14/389 371/18722 0.0237268631712325 0.22843301740512 SLC7A11/COL4A1/SPRED2/FZD5/LRP5/GLI3/MEIS2/NRP1/FBN2/KDM5B/FAT1/FZR1/TENM3/AHI1 14 GO:0060603 mammary gland duct morphogenesis 3/389 30/18722 0.0238642664193449 0.22843301740512 LRP5/KDM5B/FGFR2 3 GO:0060674 placenta blood vessel development 3/389 30/18722 0.0238642664193449 0.22843301740512 FZD5/NR2F2/SPINT1 3 GO:0090314 positive regulation of protein targeting to membrane 3/389 30/18722 0.0238642664193449 0.22843301740512 MIEF2/TCAF1/MYO1C 3 GO:0050772 positive regulation of axonogenesis 5/389 79/18722 0.0243147041720162 0.229235788524929 LRP1/STK25/NRP1/PLXNB1/CYFIP1 5 GO:0030879 mammary gland development 7/389 137/18722 0.0244692980623359 0.229235788524929 ELF3/LRP5/GLI3/KDM5B/FGFR2/PRLR/XBP1 7 GO:0006534 cysteine metabolic process 2/389 12/18722 0.0247652593032142 0.229235788524929 SLC7A11/MPST 2 GO:0007320 insemination 2/389 12/18722 0.0247652593032142 0.229235788524929 ACVR2A/SERPINE2 2 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway 2/389 12/18722 0.0247652593032142 0.229235788524929 LRP1/HGS 2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway 2/389 12/18722 0.0247652593032142 0.229235788524929 COL4A1/COL4A2 2 GO:0042762 regulation of sulfur metabolic process 2/389 12/18722 0.0247652593032142 0.229235788524929 SLC7A11/PDK2 2 GO:0048548 regulation of pinocytosis 2/389 12/18722 0.0247652593032142 0.229235788524929 PROM2/CLN3 2 GO:0051255 spindle midzone assembly 2/389 12/18722 0.0247652593032142 0.229235788524929 MAP10/RACGAP1 2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 2/389 12/18722 0.0247652593032142 0.229235788524929 PPARG/LRP1 2 GO:0061430 bone trabecula morphogenesis 2/389 12/18722 0.0247652593032142 0.229235788524929 FBN2/PLXNB1 2 GO:0072584 caveolin-mediated endocytosis 2/389 12/18722 0.0247652593032142 0.229235788524929 PROM2/CLN3 2 GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance 2/389 12/18722 0.0247652593032142 0.229235788524929 NRP1/PLXNB1 2 GO:0048588 developmental cell growth 10/389 234/18722 0.0248922339449977 0.229724579180271 SEMA4G/SYT1/SEMA6A/COBL/LRP1/WASF1/NRP1/ABL1/CDKL3/CYFIP1 10 GO:0050708 regulation of protein secretion 11/389 268/18722 0.0249440453401117 0.229724579180271 UNC13B/RHBDF1/LRP5/GJA1/WLS/LRP1/RAB11FIP3/HMGCR/P3H1/SLC16A1/EGFR 11 GO:0007162 negative regulation of cell adhesion 12/389 303/18722 0.0251700385519375 0.231221991433038 SEMA6A/CDH1/GLI3/LRP1/JAM3/GCNT2/ABL1/MMP14/PLXNB1/SERPINE2/ERBB3/PTK2 12 GO:0032388 positive regulation of intracellular transport 9/389 202/18722 0.0256928400569711 0.234850030622536 FZD5/CDH1/GLI3/TMEM30B/MIEF2/TCAF1/TM9SF4/DYNC1H1/MYO1C 9 GO:0150063 visual system development 14/389 375/18722 0.0256937653464195 0.234850030622536 SLC7A11/COL4A1/SPRED2/FZD5/LRP5/GLI3/MEIS2/NRP1/FBN2/KDM5B/FAT1/FZR1/TENM3/AHI1 14 GO:0036474 cell death in response to hydrogen peroxide 3/389 31/18722 0.0260241712929591 0.236683672582099 MET/STK25/SIGMAR1 3 GO:0060390 regulation of SMAD protein signal transduction 3/389 31/18722 0.0260241712929591 0.236683672582099 PBLD/PPARG/LRP1 3 GO:0051701 biological process involved in interaction with host 9/389 203/18722 0.0264130684854451 0.239623036732384 DAG1/SCARB2/TFRC/NRP1/ITGB5/TRIM27/ITGAV/EGFR/ANO6 9 GO:0001942 hair follicle development 5/389 81/18722 0.0267411461079187 0.240802370013777 LGR5/FZD3/FGFR2/LAMA5/EGFR 5 GO:0008589 regulation of smoothened signaling pathway 5/389 81/18722 0.0267411461079187 0.240802370013777 DCDC2/GAS1/GLI3/FGFR2/SERPINE2 5 GO:0048708 astrocyte differentiation 5/389 81/18722 0.0267411461079187 0.240802370013777 LRP1/ABL1/SERPINE2/IL6ST/EGFR 5 GO:0006650 glycerophospholipid metabolic process 12/389 306/18722 0.026890119676933 0.241547454339347 SYNJ2/TTC7B/SLC44A5/AGPAT4/CDS1/MBOAT7/SLC44A2/PIGV/CLN3/SERAC1/INPP4A/ABHD12 12 GO:0015748 organophosphate ester transport 7/389 140/18722 0.0271294763739407 0.243098772323739 GJA1/TMEM30B/SCARB2/PLSCR4/XKR8/SLC25A4/ANO6 7 GO:0001755 neural crest cell migration 4/389 55/18722 0.0272647561587683 0.243386019454668 SEMA4G/SEMA6A/NRP1/LAMA5 4 GO:0014812 muscle cell migration 6/389 110/18722 0.0272992125580111 0.243386019454668 PLAU/ADAMTS1/LRP1/NRP1/DOCK5/TRIB1 6 GO:0050878 regulation of body fluid levels 14/389 379/18722 0.0277792019660643 0.243386019454668 MET/F5/PLAU/SLC7A11/GJA1/CLDN4/LSR/SERPINE2/GGCX/PRLR/IL6ST/EGFR/XBP1/ANO6 14 GO:0010498 proteasomal protein catabolic process 17/389 490/18722 0.0279435616555681 0.243386019454668 UGGT2/RHBDF1/UBXN8/FBXO45/HACE1/HECTD3/TMTC3/RMND5B/USP5/FZR1/TRIB1/CEBPA/CUL2/KLHL42/SKP2/PSMD2/RNF19B 17 GO:0032355 response to estradiol 7/389 141/18722 0.0280582324696767 0.243386019454668 MMP15/NR2F2/GJA1/DNMT3A/PCNA/EZH2/EGFR 7 GO:0006909 phagocytosis 12/389 308/18722 0.0280834756561987 0.243386019454668 MET/IGLL1/LRP1/RAB7B/ABL1/CLN3/TMEM175/XKR8/TM9SF4/ITGAV/PTK2/ANO6 12 GO:0010743 regulation of macrophage derived foam cell differentiation 3/389 32/18722 0.0282853532744341 0.243386019454668 PRKCH/PPARG/ITGAV 3 GO:0048841 regulation of axon extension involved in axon guidance 3/389 32/18722 0.0282853532744341 0.243386019454668 SEMA4G/SEMA6A/NRP1 3 GO:0072337 modified amino acid transport 3/389 32/18722 0.0282853532744341 0.243386019454668 LRP2/SLC7A11/GJA1 3 GO:0030336 negative regulation of cell migration 13/389 344/18722 0.0283560845668562 0.243386019454668 SRGAP3/EPHA1/MARVELD3/PPARG/NR2F2/GJA1/DAG1/CDH1/LRP1/CLDN3/TRIB1/TCAF1/ADGRG1 13 GO:0051099 positive regulation of binding 8/389 173/18722 0.028412168445594 0.243386019454668 MET/BAMBI/PPARG/LRP1/NRP1/ABL1/RAPGEF2/STK3 8 GO:0048880 sensory system development 14/389 381/18722 0.0288675474530773 0.243386019454668 SLC7A11/COL4A1/SPRED2/FZD5/LRP5/GLI3/MEIS2/NRP1/FBN2/KDM5B/FAT1/FZR1/TENM3/AHI1 14 GO:0010745 negative regulation of macrophage derived foam cell differentiation 2/389 13/18722 0.0288716378081114 0.243386019454668 PPARG/ITGAV 2 GO:0015809 arginine transport 2/389 13/18722 0.0288716378081114 0.243386019454668 SLC38A9/CLN3 2 GO:0016024 CDP-diacylglycerol biosynthetic process 2/389 13/18722 0.0288716378081114 0.243386019454668 AGPAT4/CDS1 2 GO:0032429 regulation of phospholipase A2 activity 2/389 13/18722 0.0288716378081114 0.243386019454668 LRP1/EGFR 2 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway 2/389 13/18722 0.0288716378081114 0.243386019454668 YAP1/SKP2 2 GO:0035331 negative regulation of hippo signaling 2/389 13/18722 0.0288716378081114 0.243386019454668 WWC1/WWC3 2 GO:0048012 hepatocyte growth factor receptor signaling pathway 2/389 13/18722 0.0288716378081114 0.243386019454668 MET/NRP1 2 GO:0048711 positive regulation of astrocyte differentiation 2/389 13/18722 0.0288716378081114 0.243386019454668 SERPINE2/IL6ST 2 GO:0060347 heart trabecula formation 2/389 13/18722 0.0288716378081114 0.243386019454668 ADAMTS1/FHL2 2 GO:1900115 extracellular regulation of signal transduction 2/389 13/18722 0.0288716378081114 0.243386019454668 LTBP1/FBN2 2 GO:1900116 extracellular negative regulation of signal transduction 2/389 13/18722 0.0288716378081114 0.243386019454668 LTBP1/FBN2 2 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance 2/389 13/18722 0.0288716378081114 0.243386019454668 NRP1/PLXNB1 2 GO:0022029 telencephalon cell migration 4/389 56/18722 0.0288966675140859 0.243386019454668 MBOAT7/GLI3/FBXO45/ADGRG1 4 GO:0031122 cytoplasmic microtubule organization 4/389 56/18722 0.0288966675140859 0.243386019454668 DST/MAP10/CLIP1/DYNC1H1 4 GO:0007009 plasma membrane organization 7/389 142/18722 0.029008324036039 0.243763497141554 CLN3/EPB41L3/MICALL1/PLSCR4/XKR8/MYOF/ANO6 7 GO:0046785 microtubule polymerization 5/389 83/18722 0.0293167452658981 0.245225160515437 MET/ABL1/ARL3/CLIP1/FKBP4 5 GO:0048678 response to axon injury 5/389 83/18722 0.0293167452658981 0.245225160515437 DAG1/NREP/LRP1/LRIG2/JAM3 5 GO:0009314 response to radiation 16/389 456/18722 0.0295912461865877 0.246954862339783 SLC7A11/ELK1/SLC1A3/CDS1/LRP5/DNMT3A/DCUN1D3/MEIS2/YAP1/SCARA3/HMGCR/PCNA/BLM/AEN/EGFR/SPRTN 16 GO:0030010 establishment of cell polarity 7/389 143/18722 0.0299799359915344 0.249627457902114 WWC1/MYO9A/GJA1/JAM3/FAT1/MPP7/PTK2 7 GO:0052126 movement in host environment 8/389 175/18722 0.0301355907948787 0.250159863436053 DAG1/SCARB2/TFRC/NRP1/ITGB5/TRIM27/ITGAV/EGFR 8 GO:0003382 epithelial cell morphogenesis 3/389 33/18722 0.0306474677735342 0.250159863436053 MET/CLDN3/FAT1 3 GO:0031116 positive regulation of microtubule polymerization 3/389 33/18722 0.0306474677735342 0.250159863436053 MET/ARL3/CLIP1 3 GO:0048333 mesodermal cell differentiation 3/389 33/18722 0.0306474677735342 0.250159863436053 ITGB4/GJA1/FGFR2 3 GO:0150117 positive regulation of cell-substrate junction organization 3/389 33/18722 0.0306474677735342 0.250159863436053 NRP1/ABL1/FERMT2 3 GO:1902692 regulation of neuroblast proliferation 3/389 33/18722 0.0306474677735342 0.250159863436053 ASPM/FZD3/GLI3 3 GO:0002088 lens development in camera-type eye 5/389 84/18722 0.0306612171527051 0.250159863436053 SLC7A11/SPRED2/KDM5B/FAT1/FZR1 5 GO:0022404 molting cycle process 5/389 84/18722 0.0306612171527051 0.250159863436053 LGR5/FZD3/FGFR2/LAMA5/EGFR 5 GO:0022405 hair cycle process 5/389 84/18722 0.0306612171527051 0.250159863436053 LGR5/FZD3/FGFR2/LAMA5/EGFR 5 GO:1901800 positive regulation of proteasomal protein catabolic process 6/389 114/18722 0.031764797276014 0.257836651072398 TMTC3/USP5/FZR1/TRIB1/CEBPA/RNF19B 6 GO:0006898 receptor-mediated endocytosis 10/389 244/18722 0.0319025362016547 0.257836651072398 LRP2/LRP1/WASF1/SCARB2/TFRC/AAK1/CLN3/MICALL1/AHI1/ITGAV 10 GO:0098773 skin epidermis development 5/389 85/18722 0.032043827374449 0.257836651072398 LGR5/FZD3/FGFR2/LAMA5/EGFR 5 GO:0009100 glycoprotein metabolic process 14/389 387/18722 0.0323206071875612 0.257836651072398 UGGT2/CYTL1/CHPF/PMM1/GCNT2/TMTC2/TMTC3/GLCE/GALNT11/HS6ST2/EXTL2/CHST11/CHST14/GPC1 14 GO:0018208 peptidyl-proline modification 4/389 58/18722 0.0323311552856441 0.257836651072398 P3H2/PPIL1/P3H1/FKBP4 4 GO:0097035 regulation of membrane lipid distribution 4/389 58/18722 0.0323311552856441 0.257836651072398 TMEM30B/PLSCR4/XKR8/ANO6 4 GO:1902808 positive regulation of cell cycle G1/S phase transition 4/389 58/18722 0.0323311552856441 0.257836651072398 ADAMTS1/ANKRD17/EZH2/EGFR 4 GO:0030100 regulation of endocytosis 9/389 211/18722 0.0326951961515084 0.257836651072398 PROM2/LRP1/AAK1/ABL1/CLN3/AHI1/ITGAV/RAB5B/ANO6 9 GO:0006521 regulation of cellular amino acid metabolic process 2/389 14/18722 0.0332281946816636 0.257836651072398 SLC7A11/CLN3 2 GO:0009071 serine family amino acid catabolic process 2/389 14/18722 0.0332281946816636 0.257836651072398 GLDC/SHMT1 2 GO:0010421 hydrogen peroxide-mediated programmed cell death 2/389 14/18722 0.0332281946816636 0.257836651072398 MET/STK25 2 GO:0035672 oligopeptide transmembrane transport 2/389 14/18722 0.0332281946816636 0.257836651072398 SLC7A11/GJA1 2 GO:0043455 regulation of secondary metabolic process 2/389 14/18722 0.0332281946816636 0.257836651072398 SLC7A11/RAPGEF2 2 GO:0045579 positive regulation of B cell differentiation 2/389 14/18722 0.0332281946816636 0.257836651072398 MMP14/XBP1 2 GO:0046341 CDP-diacylglycerol metabolic process 2/389 14/18722 0.0332281946816636 0.257836651072398 AGPAT4/CDS1 2 GO:0046655 folic acid metabolic process 2/389 14/18722 0.0332281946816636 0.257836651072398 SHMT1/MTHFD2L 2 GO:0048021 regulation of melanin biosynthetic process 2/389 14/18722 0.0332281946816636 0.257836651072398 SLC7A11/RAPGEF2 2 GO:0050667 homocysteine metabolic process 2/389 14/18722 0.0332281946816636 0.257836651072398 MPST/BLMH 2 GO:0050872 white fat cell differentiation 2/389 14/18722 0.0332281946816636 0.257836651072398 PPARG/CEBPA 2 GO:0055057 neuroblast division 2/389 14/18722 0.0332281946816636 0.257836651072398 ASPM/FGFR2 2 GO:0060576 intestinal epithelial cell development 2/389 14/18722 0.0332281946816636 0.257836651072398 YAP1/IL6ST 2 GO:0071285 cellular response to lithium ion 2/389 14/18722 0.0332281946816636 0.257836651072398 CDH1/CEBPA 2 GO:1900376 regulation of secondary metabolite biosynthetic process 2/389 14/18722 0.0332281946816636 0.257836651072398 SLC7A11/RAPGEF2 2 GO:1903510 mucopolysaccharide metabolic process 5/389 86/18722 0.0334648203097072 0.258661780868708 CHPF/GLCE/ITIH5/CHST11/CHST14 5 GO:0050808 synapse organization 15/389 426/18722 0.0335470835630989 0.258661780868708 EPHB3/SLC7A11/UNC13B/COL4A1/FZD5/DAG1/CDH1/WASF1/FBXO45/NRP1/TPBG/ABL1/CLN3/PLXNB1/CYFIP1 15 GO:0006469 negative regulation of protein kinase activity 9/389 212/18722 0.0335473052785574 0.258661780868708 EPHA1/PPARG/LRP5/NR2F2/ABL1/HMGCR/TRIB1/TRIM27/CEBPA 9 GO:1902850 microtubule cytoskeleton organization involved in mitosis 7/389 147/18722 0.0340851079833243 0.26207857828018 MAP10/CENPE/GJA1/TACC2/KIF11/RACGAP1/DYNC1H1 7 GO:0021885 forebrain cell migration 4/389 59/18722 0.0341341718352305 0.26207857828018 MBOAT7/GLI3/FBXO45/ADGRG1 4 GO:0015711 organic anion transport 13/389 354/18722 0.0345436421373584 0.264665258140643 LRP2/SLC7A11/SLC1A3/GJA1/SLC38A9/SLC22A11/CLN3/SLC27A6/SLC26A2/SLC25A11/SLC16A1/SLC25A4/SLC2A1 13 GO:1900182 positive regulation of protein localization to nucleus 5/389 87/18722 0.0349244217254514 0.267021731724782 CDH1/GLI3/TFRC/YAP1/FERMT2 5 GO:0035148 tube formation 7/389 148/18722 0.0351669164201755 0.267140762497503 LRP2/COBL/FZD3/ABL1/FGFR2/SPINT1/STK3 7 GO:0001569 branching involved in blood vessel morphogenesis 3/389 35/18722 0.035672484600023 0.267140762497503 COL4A1/NRP1/ABL1 3 GO:0001893 maternal placenta development 3/389 35/18722 0.035672484600023 0.267140762497503 CTSV/NR2F2/GJA1 3 GO:0006298 mismatch repair 3/389 35/18722 0.035672484600023 0.267140762497503 ABL1/PCNA/TDG 3 GO:0015695 organic cation transport 3/389 35/18722 0.035672484600023 0.267140762497503 SLC44A5/SLC19A3/SLC44A2 3 GO:0034331 cell junction maintenance 3/389 35/18722 0.035672484600023 0.267140762497503 TJP1/CLDN3/FERMT2 3 GO:0045907 positive regulation of vasoconstriction 3/389 35/18722 0.035672484600023 0.267140762497503 GJA1/HMGCR/EGFR 3 GO:0050654 chondroitin sulfate proteoglycan metabolic process 3/389 35/18722 0.035672484600023 0.267140762497503 CYTL1/CHPF/CHST11 3 GO:0071108 protein K48-linked deubiquitination 3/389 35/18722 0.035672484600023 0.267140762497503 OTUD3/USP5/USP27X 3 GO:0097502 mannosylation 3/389 35/18722 0.035672484600023 0.267140762497503 PIGV/TMTC2/TMTC3 3 GO:0072659 protein localization to plasma membrane 11/389 284/18722 0.0358346135501769 0.267804991019458 PRKCH/TTC7B/CDH1/LRP1/TPBG/MMP14/CLN3/EPB41L3/LAMA5/RAPGEF2/EGFR 11 GO:1905039 carboxylic acid transmembrane transport 7/389 149/18722 0.0362712460920904 0.270513771979251 LRP2/SLC7A11/SLC1A3/SLC38A9/SLC25A11/SLC16A1/SLC2A1 7 GO:0001843 neural tube closure 5/389 88/18722 0.0364228387688896 0.270537867597027 LRP2/COBL/FZD3/ABL1/SPINT1 5 GO:0031110 regulation of microtubule polymerization or depolymerization 5/389 88/18722 0.0364228387688896 0.270537867597027 MET/ABL1/ARL3/CLIP1/FKBP4 5 GO:1903825 organic acid transmembrane transport 7/389 150/18722 0.0373982449795683 0.272980113421387 LRP2/SLC7A11/SLC1A3/SLC38A9/SLC25A11/SLC16A1/SLC2A1 7 GO:0006825 copper ion transport 2/389 15/18722 0.0378228177089366 0.272980113421387 ATP7B/FKBP4 2 GO:0010832 negative regulation of myotube differentiation 2/389 15/18722 0.0378228177089366 0.272980113421387 BHLHE41/XBP1 2 GO:0019511 peptidyl-proline hydroxylation 2/389 15/18722 0.0378228177089366 0.272980113421387 P3H2/P3H1 2 GO:0032488 Cdc42 protein signal transduction 2/389 15/18722 0.0378228177089366 0.272980113421387 NRP1/ABL1 2 GO:0045217 cell-cell junction maintenance 2/389 15/18722 0.0378228177089366 0.272980113421387 TJP1/FERMT2 2 GO:0051127 positive regulation of actin nucleation 2/389 15/18722 0.0378228177089366 0.272980113421387 WASF1/CYFIP1 2 GO:0051938 L-glutamate import 2/389 15/18722 0.0378228177089366 0.272980113421387 SLC7A11/SLC1A3 2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum 2/389 15/18722 0.0378228177089366 0.272980113421387 TMEM30B/TM9SF4 2 GO:0071599 otic vesicle development 2/389 15/18722 0.0378228177089366 0.272980113421387 FGFR2/AHI1 2 GO:0097468 programmed cell death in response to reactive oxygen species 2/389 15/18722 0.0378228177089366 0.272980113421387 MET/STK25 2 GO:0098712 L-glutamate import across plasma membrane 2/389 15/18722 0.0378228177089366 0.272980113421387 SLC7A11/SLC1A3 2 GO:0099170 postsynaptic modulation of chemical synaptic transmission 2/389 15/18722 0.0378228177089366 0.272980113421387 CDH1/CYFIP1 2 GO:1900029 positive regulation of ruffle assembly 2/389 15/18722 0.0378228177089366 0.272980113421387 COBL/CYFIP1 2 GO:0060606 tube closure 5/389 89/18722 0.037960259977792 0.272980113421387 LRP2/COBL/FZD3/ABL1/SPINT1 5 GO:2000146 negative regulation of cell motility 13/389 359/18722 0.0379769954979142 0.272980113421387 SRGAP3/EPHA1/MARVELD3/PPARG/NR2F2/GJA1/DAG1/CDH1/LRP1/CLDN3/TRIB1/TCAF1/ADGRG1 13 GO:0009225 nucleotide-sugar metabolic process 3/389 36/18722 0.0383340884210341 0.272980113421387 UGGT2/PMM1/EXTL2 3 GO:0010092 specification of animal organ identity 3/389 36/18722 0.0383340884210341 0.272980113421387 LRP2/GLI3/FGFR2 3 GO:0038179 neurotrophin signaling pathway 3/389 36/18722 0.0383340884210341 0.272980113421387 WASF1/CYFIP1/RAPGEF2 3 GO:0045746 negative regulation of Notch signaling pathway 3/389 36/18722 0.0383340884210341 0.272980113421387 EGFL7/CBFA2T2/MMP14 3 GO:0090313 regulation of protein targeting to membrane 3/389 36/18722 0.0383340884210341 0.272980113421387 MIEF2/TCAF1/MYO1C 3 GO:0045017 glycerolipid biosynthetic process 10/389 252/18722 0.0384324928484869 0.272980113421387 SYNJ2/TTC7B/SLC44A5/AGPAT4/CDS1/MBOAT7/SLC44A2/PIGV/CLN3/INPP4A 10 GO:0030902 hindbrain development 7/389 151/18722 0.0385480555009636 0.272980113421387 WLS/ABL1/RBFOX2/SERPINE2/AHI1/EZH2/PSMG1 7 GO:0048592 eye morphogenesis 7/389 151/18722 0.0385480555009636 0.272980113421387 FZD5/LRP5/GLI3/FBN2/FAT1/TENM3/AHI1 7 GO:0007052 mitotic spindle organization 6/389 120/18722 0.03931249456425 0.276781211729382 MAP10/CENPE/TACC2/KIF11/RACGAP1/DYNC1H1 6 GO:0048593 camera-type eye morphogenesis 6/389 120/18722 0.03931249456425 0.276781211729382 FZD5/LRP5/GLI3/FAT1/TENM3/AHI1 6 GO:0071901 negative regulation of protein serine/threonine kinase activity 6/389 120/18722 0.03931249456425 0.276781211729382 PPARG/LRP5/NR2F2/ABL1/HMGCR/CEBPA 6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 5/389 90/18722 0.0395368553087022 0.277824491928395 USP5/FZR1/TRIB1/CEBPA/RNF19B 5 GO:0021915 neural tube development 7/389 152/18722 0.0397208144520249 0.278580404435644 LRP2/COBL/FZD3/GLI3/ABL1/SPINT1/STK3 7 GO:0046148 pigment biosynthetic process 4/389 62/18722 0.0398880502479703 0.278681454510245 SLC7A11/COX10/SHMT1/RAPGEF2 4 GO:1903078 positive regulation of protein localization to plasma membrane 4/389 62/18722 0.0398880502479703 0.278681454510245 PRKCH/LRP1/CLN3/EGFR 4 GO:0050673 epithelial cell proliferation 15/389 437/18722 0.0404621126563503 0.282151672768087 LGR5/EGFL7/MARVELD3/PPARG/ACVR2A/NR2F2/GJA1/YAP1/NRP1/KDM5B/MMP14/LAMC1/FGFR2/EGFR/XBP1 15 GO:0001838 embryonic epithelial tube formation 6/389 121/18722 0.0406718899928837 0.282534062483899 LRP2/COBL/FZD3/ABL1/SPINT1/STK3 6 GO:0048706 embryonic skeletal system development 6/389 121/18722 0.0406718899928837 0.282534062483899 ACVR2A/GLI3/MMP14/FGFR2/SLC39A1/CHST11 6 GO:0044706 multi-multicellular organism process 9/389 220/18722 0.0409215642351218 0.283177688183631 ITGB4/CTSV/ACVR2A/NR2F2/GJA1/CLDN4/SERPINE2/PRLR/SLC2A1 9 GO:0031112 positive regulation of microtubule polymerization or depolymerization 3/389 37/18722 0.0410940417633951 0.283177688183631 MET/ARL3/CLIP1 3 GO:0048846 axon extension involved in axon guidance 3/389 37/18722 0.0410940417633951 0.283177688183631 SEMA4G/SEMA6A/NRP1 3 GO:1902284 neuron projection extension involved in neuron projection guidance 3/389 37/18722 0.0410940417633951 0.283177688183631 SEMA4G/SEMA6A/NRP1 3 GO:0002065 columnar/cuboidal epithelial cell differentiation 5/389 91/18722 0.0411527761824306 0.283177688183631 CBFA2T2/YAP1/ABL1/FGFR2/IL6ST 5 GO:0008406 gonad development 9/389 221/18722 0.0419145330779098 0.286841623189446 ASPM/LRP2/ADAMTS1/CTSV/ACVR2A/NR2F2/ZFX/MMP14/ADGRG1 9 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 9/389 221/18722 0.0419145330779098 0.286841623189446 RHBDF1/TMTC3/USP5/MAGEF1/FZR1/TRIB1/CEBPA/PTK2/RNF19B 9 GO:0032233 positive regulation of actin filament bundle assembly 4/389 63/18722 0.0419211914340484 0.286841623189446 EPHA1/NRP1/ABL1/FERMT2 4 GO:0006544 glycine metabolic process 2/389 16/18722 0.042643787735033 0.286940763597169 GLDC/SHMT1 2 GO:0006857 oligopeptide transport 2/389 16/18722 0.042643787735033 0.286940763597169 SLC7A11/GJA1 2 GO:0035751 regulation of lysosomal lumen pH 2/389 16/18722 0.042643787735033 0.286940763597169 CLN3/TMEM175 2 GO:0036342 post-anal tail morphogenesis 2/389 16/18722 0.042643787735033 0.286940763597169 FZD3/CHST11 2 GO:0048557 embryonic digestive tract morphogenesis 2/389 16/18722 0.042643787735033 0.286940763597169 GLI3/FGFR2 2 GO:0061548 ganglion development 2/389 16/18722 0.042643787735033 0.286940763597169 FZD3/NRP1 2 GO:0097284 hepatocyte apoptotic process 2/389 16/18722 0.042643787735033 0.286940763597169 DNMT3A/STK3 2 GO:0099010 modification of postsynaptic structure 2/389 16/18722 0.042643787735033 0.286940763597169 WASF1/CYFIP1 2 GO:2001224 positive regulation of neuron migration 2/389 16/18722 0.042643787735033 0.286940763597169 SEMA6A/RAPGEF2 2 GO:0035249 synaptic transmission, glutamatergic 5/389 92/18722 0.0428081555462309 0.287516285961518 UNC13B/SYT1/CLN3/SERPINE2/EGFR 5 GO:0030308 negative regulation of cell growth 8/389 188/18722 0.0431054954265857 0.288450902423409 SEMA4G/SEMA6A/GJA1/DCBLD2/DCUN1D3/NRP1/CDKL3/SERPINE2 8 GO:0048839 inner ear development 8/389 188/18722 0.0431054954265857 0.288450902423409 LGR5/CYTL1/FZD3/GLI3/FGFR2/ESRP1/CEBPA/AHI1 8 GO:0001822 kidney development 11/389 293/18722 0.0432501144816266 0.288888585191378 LRP2/PYGO1/ADAMTS1/MPST/GLI3/YAP1/NRP1/FGFR2/LAMA5/ARL3/AHI1 11 GO:0043410 positive regulation of MAPK cascade 16/389 480/18722 0.0438442710592938 0.289210000346413 WWC1/FZD5/LRP1/GCNT2/STK25/NRP1/TPBG/ABL1/FERMT2/FGFR2/HMGCR/RAPGEF2/EZH2/STK3/EGFR/SHC1 16 GO:0010742 macrophage derived foam cell differentiation 3/389 38/18722 0.0439514327796251 0.289210000346413 PRKCH/PPARG/ITGAV 3 GO:0090077 foam cell differentiation 3/389 38/18722 0.0439514327796251 0.289210000346413 PRKCH/PPARG/ITGAV 3 GO:0097242 amyloid-beta clearance 3/389 38/18722 0.0439514327796251 0.289210000346413 LRP2/LRP1/HMGCR 3 GO:0001701 in utero embryonic development 13/389 367/18722 0.0439645645003918 0.289210000346413 RUNDC1/FZD5/ELF3/NR2F2/GLI3/YAP1/SEC24C/FGFR2/CEBPA/SPINT1/STK3/SLC39A1/CHST11 13 GO:0051271 negative regulation of cellular component movement 13/389 367/18722 0.0439645645003918 0.289210000346413 SRGAP3/EPHA1/MARVELD3/PPARG/NR2F2/GJA1/DAG1/CDH1/LRP1/CLDN3/TRIB1/TCAF1/ADGRG1 13 GO:0030104 water homeostasis 4/389 64/18722 0.0440119413743513 0.289210000346413 MET/CLDN4/CLN3/LSR 4 GO:0045995 regulation of embryonic development 4/389 64/18722 0.0440119413743513 0.289210000346413 DAG1/RACGAP1/LAMA5/TDG 4 GO:0050771 negative regulation of axonogenesis 4/389 64/18722 0.0440119413743513 0.289210000346413 SEMA4G/SEMA6A/NRP1/CDKL3 4 GO:0001837 epithelial to mesenchymal transition 7/389 157/18722 0.0459332230603008 0.298776825676998 BAMBI/SPRED2/DAG1/GCNT2/FERMT2/FGFR2/EZH2 7 GO:0015909 long-chain fatty acid transport 4/389 65/18722 0.0461602516093015 0.298776825676998 SLC27A2/PPARG/SLC27A6/SLC2A1 4 GO:0070613 regulation of protein processing 4/389 65/18722 0.0461602516093015 0.298776825676998 GAS1/MMP14/CLN3/SERPINE2 4 GO:0014020 primary neural tube formation 5/389 94/18722 0.0462377296503362 0.298776825676998 LRP2/COBL/FZD3/ABL1/SPINT1 5 GO:0048704 embryonic skeletal system morphogenesis 5/389 94/18722 0.0462377296503362 0.298776825676998 GLI3/MMP14/FGFR2/SLC39A1/CHST11 5 GO:1990830 cellular response to leukemia inhibitory factor 5/389 94/18722 0.0462377296503362 0.298776825676998 PMM1/TFRC/KDM5B/SHMT1/HELLS 5 GO:1904375 regulation of protein localization to cell periphery 6/389 125/18722 0.0464047309657485 0.298776825676998 PRKCH/DAG1/LRP1/MMP14/CLN3/EGFR 6 GO:0031507 heterochromatin assembly 3/389 39/18722 0.0469052562396399 0.298776825676998 DNMT3A/SUV39H1/HELLS 3 GO:0034314 Arp2/3 complex-mediated actin nucleation 3/389 39/18722 0.0469052562396399 0.298776825676998 WASF1/TRIM27/CYFIP1 3 GO:0051154 negative regulation of striated muscle cell differentiation 3/389 39/18722 0.0469052562396399 0.298776825676998 EZH2/BHLHE41/XBP1 3 GO:1902742 apoptotic process involved in development 3/389 39/18722 0.0469052562396399 0.298776825676998 FZD5/LRP5/XKR8 3 GO:2000249 regulation of actin cytoskeleton reorganization 3/389 39/18722 0.0469052562396399 0.298776825676998 TJP1/NRP1/ABL1 3 GO:0015867 ATP transport 2/389 17/18722 0.0476797676292879 0.298776825676998 GJA1/SLC25A4 2 GO:0030903 notochord development 2/389 17/18722 0.0476797676292879 0.298776825676998 COBL/YAP1 2 GO:0033623 regulation of integrin activation 2/389 17/18722 0.0476797676292879 0.298776825676998 JAM3/FERMT2 2 GO:0035269 protein O-linked mannosylation 2/389 17/18722 0.0476797676292879 0.298776825676998 TMTC2/TMTC3 2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process 2/389 17/18722 0.0476797676292879 0.298776825676998 SYNJ2/INPP4A 2 GO:0038065 collagen-activated signaling pathway 2/389 17/18722 0.0476797676292879 0.298776825676998 COL4A1/COL4A2 2 GO:0042953 lipoprotein transport 2/389 17/18722 0.0476797676292879 0.298776825676998 PPARG/LRP1 2 GO:0043117 positive regulation of vascular permeability 2/389 17/18722 0.0476797676292879 0.298776825676998 TJP1/TJP2 2 GO:0044539 long-chain fatty acid import into cell 2/389 17/18722 0.0476797676292879 0.298776825676998 SLC27A2/SLC2A1 2 GO:0045198 establishment of epithelial cell apical/basal polarity 2/389 17/18722 0.0476797676292879 0.298776825676998 MYO9A/FAT1 2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter 2/389 17/18722 0.0476797676292879 0.298776825676998 UNC13B/SYT1 2 GO:0060977 coronary vasculature morphogenesis 2/389 17/18722 0.0476797676292879 0.298776825676998 LRP2/NRP1 2 GO:0061450 trophoblast cell migration 2/389 17/18722 0.0476797676292879 0.298776825676998 ITGB4/GJA1 2 GO:0140354 lipid import into cell 2/389 17/18722 0.0476797676292879 0.298776825676998 SLC27A2/SLC2A1 2 GO:1902358 sulfate transmembrane transport 2/389 17/18722 0.0476797676292879 0.298776825676998 SLC26A2/SLC25A11 2 GO:1990823 response to leukemia inhibitory factor 5/389 95/18722 0.0480120986985745 0.299916553779626 PMM1/TFRC/KDM5B/SHMT1/HELLS 5 GO:0045862 positive regulation of proteolysis 13/389 372/18722 0.0480261221297783 0.299916553779626 PPARG/CLDN4/CLDN3/MMP14/TMTC3/USP5/MAGEF1/FZR1/TRIB1/CEBPA/PTK2/RNF19B/NLRP2 13 GO:0045137 development of primary sexual characteristics 9/389 227/18722 0.0482141240361144 0.300575915144802 ASPM/LRP2/ADAMTS1/CTSV/ACVR2A/NR2F2/ZFX/MMP14/ADGRG1 9 GO:0019229 regulation of vasoconstriction 4/389 66/18722 0.0483660353935128 0.301008414812527 GJA1/DOCK5/HMGCR/EGFR 4 GO:0015914 phospholipid transport 5/389 96/18722 0.0498262750843634 0.306810951855314 TMEM30B/SCARB2/PLSCR4/XKR8/ANO6 5 GO:0042632 cholesterol homeostasis 5/389 96/18722 0.0498262750843634 0.306810951855314 LRP5/HMGCR/TMEM97/LIMA1/XBP1 5 GO:0032386 regulation of intracellular transport 12/389 337/18722 0.0499429193782753 0.306810951855314 WWC1/FZD5/GAS1/CDH1/GLI3/TMEM30B/NUP58/MIEF2/TCAF1/TM9SF4/DYNC1H1/MYO1C 12 GO:0062197 cellular response to chemical stress 12/389 337/18722 0.0499429193782753 0.306810951855314 MET/SLC7A11/PDK2/STK25/ABL1/CLN3/SIGMAR1/AIFM2/PCNA/EZH2/SLC2A1/EGFR 12 GO:0006730 one-carbon metabolic process 3/389 40/18722 0.0499544196011404 0.306810951855314 CA8/SHMT1/MTHFD2L 3 GO:0030501 positive regulation of bone mineralization 3/389 40/18722 0.0499544196011404 0.306810951855314 ACVR2A/FBN2/ANO6 3 GO:1901661 quinone metabolic process 3/389 40/18722 0.0499544196011404 0.306810951855314 AIFM2/HMGCR/COQ9 3 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 14/389 412/18722 0.0499714026328645 0.306810951855314 UBXN8/FBXO45/HACE1/HECTD3/RMND5B/USP5/FZR1/TRIB1/CEBPA/CUL2/KLHL42/SKP2/PSMD2/RNF19B 14 GO:0033157 regulation of intracellular protein transport 9/389 229/18722 0.050446117785756 0.307740962928779 FZD5/CDH1/GLI3/TMEM30B/NUP58/MIEF2/TCAF1/TM9SF4/MYO1C 9 GO:0045444 fat cell differentiation 9/389 229/18722 0.050446117785756 0.307740962928779 PEX11A/CDS1/PPARG/LRP5/YAP1/FERMT2/CEBPA/STK3/XBP1 9 GO:0071695 anatomical structure maturation 9/389 229/18722 0.050446117785756 0.307740962928779 SRRM4/FZD5/PPARG/DAG1/TFCP2L1/RAC3/PLXNB1/ANKRD17/CEBPA 9 GO:0018108 peptidyl-tyrosine phosphorylation 13/389 375/18722 0.0505841277466138 0.307740962928779 MET/EPHB3/EPHA1/EPHB4/NRP1/ABL1/FGFR2/ERBB3/PRLR/PTK2/IL6ST/EGFR/SHC1 13 GO:0010517 regulation of phospholipase activity 4/389 67/18722 0.0506291685651954 0.307740962928779 LRP1/ABL1/FGFR2/EGFR 4 GO:1903317 regulation of protein maturation 4/389 67/18722 0.0506291685651954 0.307740962928779 GAS1/MMP14/CLN3/SERPINE2 4 GO:1901605 alpha-amino acid metabolic process 8/389 195/18722 0.0514186578342468 0.312019709020795 SLC7A11/MPST/BLMH/SEPHS1/CLN3/GLDC/SHMT1/MTHFD2L 8 GO:0055092 sterol homeostasis 5/389 97/18722 0.0516803008620501 0.313086473827071 LRP5/HMGCR/TMEM97/LIMA1/XBP1 5 GO:0007498 mesoderm development 6/389 129/18722 0.052615308794981 0.313994783102897 ITGB4/ACVR2A/GJA1/WLS/YAP1/FGFR2 6 GO:0021953 central nervous system neuron differentiation 7/389 162/18722 0.0527365394555245 0.313994783102897 EPHB3/GLI3/FBXO45/RAC3/NRP1/FGFR2/RAPGEF2 7 GO:0015936 coenzyme A metabolic process 2/389 18/18722 0.0529197915364997 0.313994783102897 HMGCR/COASY 2 GO:0030206 chondroitin sulfate biosynthetic process 2/389 18/18722 0.0529197915364997 0.313994783102897 CHPF/CHST11 2 GO:0034162 toll-like receptor 9 signaling pathway 2/389 18/18722 0.0529197915364997 0.313994783102897 RAB7B/IRAK4 2 GO:0044872 lipoprotein localization 2/389 18/18722 0.0529197915364997 0.313994783102897 PPARG/LRP1 2 GO:0051782 negative regulation of cell division 2/389 18/18722 0.0529197915364997 0.313994783102897 ASPM/BLM 2 GO:0051895 negative regulation of focal adhesion assembly 2/389 18/18722 0.0529197915364997 0.313994783102897 LRP1/MMP14 2 GO:0060602 branch elongation of an epithelium 2/389 18/18722 0.0529197915364997 0.313994783102897 YAP1/FGFR2 2 GO:0097094 craniofacial suture morphogenesis 2/389 18/18722 0.0529197915364997 0.313994783102897 GLI3/MMP14 2 GO:0150118 negative regulation of cell-substrate junction organization 2/389 18/18722 0.0529197915364997 0.313994783102897 LRP1/MMP14 2 GO:0051148 negative regulation of muscle cell differentiation 4/389 68/18722 0.0529494904327617 0.313994783102897 ANKRD17/EZH2/BHLHE41/XBP1 4 GO:1901607 alpha-amino acid biosynthetic process 4/389 68/18722 0.0529494904327617 0.313994783102897 SEPHS1/CLN3/SHMT1/MTHFD2L 4 GO:0018212 peptidyl-tyrosine modification 13/389 378/18722 0.0532344364943327 0.315172061517583 MET/EPHB3/EPHA1/EPHB4/NRP1/ABL1/FGFR2/ERBB3/PRLR/PTK2/IL6ST/EGFR/SHC1 13 GO:0001933 negative regulation of protein phosphorylation 12/389 342/18722 0.0546375851909029 0.322955061898254 EPHA1/SPRED2/PPARG/LRP5/NR2F2/LRP1/ABL1/HMGCR/TRIB1/TRIM27/CEBPA/DMD 12 GO:0051966 regulation of synaptic transmission, glutamatergic 4/389 69/18722 0.0553268046763579 0.325972304773308 SYT1/CLN3/SERPINE2/EGFR 4 GO:1904377 positive regulation of protein localization to cell periphery 4/389 69/18722 0.0553268046763579 0.325972304773308 PRKCH/LRP1/CLN3/EGFR 4 GO:0030838 positive regulation of actin filament polymerization 5/389 99/18722 0.0555079800559827 0.326153194987193 WASF1/CDC42EP4/TRIM27/CYFIP1/MYO1C 5 GO:0007346 regulation of mitotic cell cycle 15/389 457/18722 0.0555481534884989 0.326153194987193 CENPE/GAS1/ADAMTS1/LRP5/FZD3/DCUN1D3/MEIS2/ABL1/FZR1/BLM/ANKRD17/EZH2/E4F1/EGFR/ECD 15 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 7/389 164/18722 0.0556257985418245 0.326153194987193 USP5/MAGEF1/FZR1/TRIB1/CEBPA/PTK2/RNF19B 7 GO:0006612 protein targeting to membrane 6/389 131/18722 0.0559014234708197 0.326629691733979 ARL6/MICALL1/ICMT/MIEF2/TCAF1/MYO1C 6 GO:0006661 phosphatidylinositol biosynthetic process 6/389 131/18722 0.0559014234708197 0.326629691733979 SYNJ2/TTC7B/CDS1/MBOAT7/PIGV/INPP4A 6 GO:0000266 mitochondrial fission 3/389 42/18722 0.0563339939952489 0.326629691733979 PPARG/COX10/MIEF2 3 GO:0016601 Rac protein signal transduction 3/389 42/18722 0.0563339939952489 0.326629691733979 WASF1/HACE1/CYFIP1 3 GO:0021879 forebrain neuron differentiation 3/389 42/18722 0.0563339939952489 0.326629691733979 NRP1/FGFR2/RAPGEF2 3 GO:0030574 collagen catabolic process 3/389 42/18722 0.0563339939952489 0.326629691733979 MMP15/MMP14/MRC2 3 GO:0045773 positive regulation of axon extension 3/389 42/18722 0.0563339939952489 0.326629691733979 LRP1/NRP1/CYFIP1 3 GO:0006644 phospholipid metabolic process 13/389 383/18722 0.0578598047346878 0.333564763050586 SYNJ2/TTC7B/SLC44A5/AGPAT4/CDS1/MBOAT7/SLC44A2/PLBD1/PIGV/CLN3/SERAC1/INPP4A/ABHD12 13 GO:0015802 basic amino acid transport 2/389 19/18722 0.0583532544080816 0.333564763050586 SLC38A9/CLN3 2 GO:0031290 retinal ganglion cell axon guidance 2/389 19/18722 0.0583532544080816 0.333564763050586 EPHB3/NRP1 2 GO:0035461 vitamin transmembrane transport 2/389 19/18722 0.0583532544080816 0.333564763050586 LRP2/SLC19A3 2 GO:0044003 modulation by symbiont of host process 2/389 19/18722 0.0583532544080816 0.333564763050586 DAG1/ANO6 2 GO:0045780 positive regulation of bone resorption 2/389 19/18722 0.0583532544080816 0.333564763050586 TFRC/EGFR 2 GO:0046653 tetrahydrofolate metabolic process 2/389 19/18722 0.0583532544080816 0.333564763050586 SHMT1/MTHFD2L 2 GO:1900221 regulation of amyloid-beta clearance 2/389 19/18722 0.0583532544080816 0.333564763050586 LRP1/HMGCR 2 GO:2000251 positive regulation of actin cytoskeleton reorganization 2/389 19/18722 0.0583532544080816 0.333564763050586 NRP1/ABL1 2 GO:0048872 homeostasis of number of cells 10/389 272/18722 0.0586458826383568 0.334712885730966 SLC7A11/ACVR2A/JAM3/RAC3/ZFX/ABL1/RBFOX2/XKR8/EZH2/ADGRG1 10 GO:0009952 anterior/posterior pattern specification 8/389 201/18722 0.059315852921712 0.338007680633568 FZD5/LRP5/ACVR2A/COBL/NR2F2/WLS/GLI3/BHLHE41 8 GO:0033673 negative regulation of kinase activity 9/389 237/18722 0.0600494545567214 0.341643587242141 EPHA1/PPARG/LRP5/NR2F2/ABL1/HMGCR/TRIB1/TRIM27/CEBPA 9 GO:0055088 lipid homeostasis 7/389 167/18722 0.0601412621358526 0.341643587242141 PPARG/LRP5/HMGCR/CEBPA/TMEM97/LIMA1/XBP1 7 GO:0071230 cellular response to amino acid stimulus 4/389 71/18722 0.0602514523674508 0.341737242276972 COL4A1/DNMT3A/SLC38A9/XBP1 4 GO:0043087 regulation of GTPase activity 12/389 348/18722 0.060653737148397 0.343484750590379 MET/RUNDC1/PROM2/EPHB3/EPHA1/MYO9A/ITGA6/FERMT2/PLXNB1/RAPGEF2/EZH2/PTK2 12 GO:0042552 myelination 6/389 134/18722 0.0610577900115034 0.345236837475896 ITGB4/DAG1/JAM3/EPB41L3/CYFIP1/GPC1 6 GO:0032869 cellular response to insulin stimulus 8/389 203/18722 0.0621091094466241 0.350637650389842 ECHDC3/PPARG/PDK2/SIK2/CYFIP1/MYO1C/XBP1/SHC1 8 GO:0001707 mesoderm formation 4/389 72/18722 0.0627982233143899 0.353980093396569 ITGB4/GJA1/WLS/FGFR2 4 GO:0008542 visual learning 3/389 44/18722 0.0630798847239841 0.354472017855732 SLC7A11/MEIS2/HMGCR 3 GO:0060711 labyrinthine layer development 3/389 44/18722 0.0630798847239841 0.354472017855732 FZD5/FGFR2/SPINT1 3 GO:0045787 positive regulation of cell cycle 11/389 313/18722 0.0633546718323663 0.355096243359462 MAP10/ADAMTS1/LRP5/MEIS2/ABL1/RACGAP1/FGFR2/ANKRD17/DYNC1H1/EZH2/EGFR 11 GO:0032886 regulation of microtubule-based process 9/389 240/18722 0.0639332790347047 0.355096243359462 MET/MAP10/ABL1/CEP76/ARL3/CLIP1/DYNC1H1/FKBP4/KLHL42 9 GO:0006346 DNA methylation-dependent heterochromatin assembly 2/389 20/18722 0.0639699018061877 0.355096243359462 DNMT3A/HELLS 2 GO:0007620 copulation 2/389 20/18722 0.0639699018061877 0.355096243359462 ACVR2A/SERPINE2 2 GO:0032332 positive regulation of chondrocyte differentiation 2/389 20/18722 0.0639699018061877 0.355096243359462 GLI3/ZNF219 2 GO:0043586 tongue development 2/389 20/18722 0.0639699018061877 0.355096243359462 GLI3/EGFR 2 GO:0060252 positive regulation of glial cell proliferation 2/389 20/18722 0.0639699018061877 0.355096243359462 PRKCH/EGFR 2 GO:2000010 positive regulation of protein localization to cell surface 2/389 20/18722 0.0639699018061877 0.355096243359462 LRIG2/TM9SF4 2 GO:0007272 ensheathment of neurons 6/389 136/18722 0.0646471188352268 0.357766376922719 ITGB4/DAG1/JAM3/EPB41L3/CYFIP1/GPC1 6 GO:0008366 axon ensheathment 6/389 136/18722 0.0646471188352268 0.357766376922719 ITGB4/DAG1/JAM3/EPB41L3/CYFIP1/GPC1 6 GO:0030178 negative regulation of Wnt signaling pathway 7/389 170/18722 0.0648757218187276 0.358487511322575 RNF43/GLI3/LRP1/TPBG/TMEM170B/CTNND1/STK3 7 GO:0035924 cellular response to vascular endothelial growth factor stimulus 4/389 73/18722 0.0654008635109169 0.360297506381139 GAS1/SEMA6A/NRP1/MYO1C 4 GO:0072089 stem cell proliferation 4/389 73/18722 0.0654008635109169 0.360297506381139 GJA1/RNF43/YAP1/FERMT2 4 GO:0032963 collagen metabolic process 5/389 104/18722 0.0657741057241238 0.361262294541987 P3H2/MMP15/MMP14/MRC2/P3H1 5 GO:1903076 regulation of protein localization to plasma membrane 5/389 104/18722 0.0657741057241238 0.361262294541987 PRKCH/LRP1/MMP14/CLN3/EGFR 5 GO:0031670 cellular response to nutrient 3/389 45/18722 0.0665866979441721 0.364080490858164 PDK2/TRIM24/XBP1 3 GO:0051180 vitamin transport 3/389 45/18722 0.0665866979441721 0.364080490858164 LRP2/SLC19A3/SLC2A1 3 GO:0071354 cellular response to interleukin-6 3/389 45/18722 0.0665866979441721 0.364080490858164 YAP1/CEBPA/IL6ST 3 GO:0050679 positive regulation of epithelial cell proliferation 8/389 207/18722 0.0679390759663539 0.368877117559928 EGFL7/YAP1/NRP1/KDM5B/LAMC1/FGFR2/EGFR/XBP1 8 GO:0007040 lysosome organization 4/389 74/18722 0.0680590123968041 0.368877117559928 RAB7B/SCARB2/CLN3/TMEM175 4 GO:0046470 phosphatidylcholine metabolic process 4/389 74/18722 0.0680590123968041 0.368877117559928 SLC44A5/CDS1/MBOAT7/SLC44A2 4 GO:0048332 mesoderm morphogenesis 4/389 74/18722 0.0680590123968041 0.368877117559928 ITGB4/GJA1/WLS/FGFR2 4 GO:0080171 lytic vacuole organization 4/389 74/18722 0.0680590123968041 0.368877117559928 RAB7B/SCARB2/CLN3/TMEM175 4 GO:0007224 smoothened signaling pathway 6/389 138/18722 0.0683578751893058 0.368877117559928 DCDC2/GAS1/GLI3/FGFR2/SERPINE2/ARL3 6 GO:0035107 appendage morphogenesis 6/389 138/18722 0.0683578751893058 0.368877117559928 LRP5/GLI3/FBN2/ZNF219/FGFR2/CHST11 6 GO:0035108 limb morphogenesis 6/389 138/18722 0.0683578751893058 0.368877117559928 LRP5/GLI3/FBN2/ZNF219/FGFR2/CHST11 6 GO:0021700 developmental maturation 10/389 280/18722 0.0683742614396796 0.368877117559928 UNC13B/SRRM4/FZD5/PPARG/DAG1/TFCP2L1/RAC3/PLXNB1/ANKRD17/CEBPA 10 GO:0007249 I-kappaB kinase/NF-kappaB signaling 10/389 281/18722 0.0696583565667716 0.37094097908355 ZDHHC13/GJA1/WLS/SLC44A2/TFRC/ABL1/AZI2/TRIM27/ANKRD17/IRAK4 10 GO:0007350 blastoderm segmentation 2/389 21/18722 0.0697598199740342 0.37094097908355 FZD5/NRP1 2 GO:0008090 retrograde axonal transport 2/389 21/18722 0.0697598199740342 0.37094097908355 DST/DYNC1H1 2 GO:0009070 serine family amino acid biosynthetic process 2/389 21/18722 0.0697598199740342 0.37094097908355 SEPHS1/SHMT1 2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation 2/389 21/18722 0.0697598199740342 0.37094097908355 WASF1/CYFIP1 2 GO:0035330 regulation of hippo signaling 2/389 21/18722 0.0697598199740342 0.37094097908355 WWC1/WWC3 2 GO:0038083 peptidyl-tyrosine autophosphorylation 2/389 21/18722 0.0697598199740342 0.37094097908355 ABL1/EGFR 2 GO:0045056 transcytosis 2/389 21/18722 0.0697598199740342 0.37094097908355 LRP2/LRP1 2 GO:0048485 sympathetic nervous system development 2/389 21/18722 0.0697598199740342 0.37094097908355 FZD3/NRP1 2 GO:0010830 regulation of myotube differentiation 3/389 46/18722 0.0701807720229366 0.37094097908355 MMP14/BHLHE41/XBP1 3 GO:0050919 negative chemotaxis 3/389 46/18722 0.0701807720229366 0.37094097908355 SEMA4G/SEMA6A/ITGAV 3 GO:0070828 heterochromatin organization 3/389 46/18722 0.0701807720229366 0.37094097908355 DNMT3A/SUV39H1/HELLS 3 GO:0090329 regulation of DNA-dependent DNA replication 3/389 46/18722 0.0701807720229366 0.37094097908355 WRNIP1/PCNA/BLM 3 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 3/389 46/18722 0.0701807720229366 0.37094097908355 ADAMTS1/ANKRD17/EGFR 3 GO:0009416 response to light stimulus 11/389 320/18722 0.0716309525116687 0.378058008408185 SLC7A11/ELK1/SLC1A3/CDS1/DCUN1D3/MEIS2/SCARA3/HMGCR/PCNA/EGFR/SPRTN 11 GO:0003007 heart morphogenesis 9/389 246/18722 0.0721697625733831 0.379965139113047 LRP2/ADAMTS1/EPHB4/YAP1/NRP1/FGFR2/AHI1/PTK2/FHL2 9 GO:0006275 regulation of DNA replication 5/389 107/18722 0.0724090407687325 0.379965139113047 WRNIP1/PCNA/BLM/ANKRD17/EGFR 5 GO:0042303 molting cycle 5/389 107/18722 0.0724090407687325 0.379965139113047 LGR5/FZD3/FGFR2/LAMA5/EGFR 5 GO:0042633 hair cycle 5/389 107/18722 0.0724090407687325 0.379965139113047 LGR5/FZD3/FGFR2/LAMA5/EGFR 5 GO:0009306 protein secretion 12/389 359/18722 0.0727932246634092 0.381432313717605 UNC13B/RHBDF1/LRP5/GJA1/WLS/LRP1/RAB11FIP3/HMGCR/P3H1/SLC16A1/CAMK2G/EGFR 12 GO:0050954 sensory perception of mechanical stimulus 7/389 175/18722 0.073255070050871 0.383144675696763 LRP2/DCDC2/SRRM4/SLC1A3/LRIG2/SCARB2/SERPINE2 7 GO:0031100 animal organ regeneration 4/389 76/18722 0.0735402448554247 0.383144675696763 GLI3/PCNA/EZH2/EGFR 4 GO:0045685 regulation of glial cell differentiation 4/389 76/18722 0.0735402448554247 0.383144675696763 DAG1/SERPINE2/SPINT1/IL6ST 4 GO:0140115 export across plasma membrane 4/389 76/18722 0.0735402448554247 0.383144675696763 SLC35G1/ATP7B/GJA1/ANO6 4 GO:0043114 regulation of vascular permeability 3/389 47/18722 0.0738605534213133 0.383171320522802 TJP1/FERMT2/TJP2 3 GO:0045747 positive regulation of Notch signaling pathway 3/389 47/18722 0.0738605534213133 0.383171320522802 AAK1/YAP1/IL6ST 3 GO:0046677 response to antibiotic 3/389 47/18722 0.0738605534213133 0.383171320522802 SLC1A3/KDM5B/EZH2 3 GO:0035592 establishment of protein localization to extracellular region 12/389 360/18722 0.0739691363031393 0.38318954559311 UNC13B/RHBDF1/LRP5/GJA1/WLS/LRP1/RAB11FIP3/HMGCR/P3H1/SLC16A1/CAMK2G/EGFR 12 GO:0008584 male gonad development 6/389 141/18722 0.0741513170508223 0.383588444374963 ASPM/LRP2/CTSV/ACVR2A/MMP14/ADGRG1 6 GO:0007173 epidermal growth factor receptor signaling pathway 5/389 108/18722 0.074699230071296 0.385875484518437 RHBDF1/ABL1/PTK2/EGFR/SHC1 5 GO:0048562 embryonic organ morphogenesis 10/389 285/18722 0.07494721814649 0.386191419897451 FZD5/FZD3/GLI3/YAP1/FBN2/MMP14/FGFR2/AHI1/SLC39A1/CHST11 10 GO:0002053 positive regulation of mesenchymal cell proliferation 2/389 22/18722 0.0757134261658014 0.386191419897451 LRP5/FGFR2 2 GO:0006359 regulation of transcription by RNA polymerase III 2/389 22/18722 0.0757134261658014 0.386191419897451 POLR3F/CEBPA 2 GO:0006907 pinocytosis 2/389 22/18722 0.0757134261658014 0.386191419897451 PROM2/CLN3 2 GO:0007413 axonal fasciculation 2/389 22/18722 0.0757134261658014 0.386191419897451 EPHB3/NRP1 2 GO:0035089 establishment of apical/basal cell polarity 2/389 22/18722 0.0757134261658014 0.386191419897451 MYO9A/FAT1 2 GO:0035268 protein mannosylation 2/389 22/18722 0.0757134261658014 0.386191419897451 TMTC2/TMTC3 2 GO:0060444 branching involved in mammary gland duct morphogenesis 2/389 22/18722 0.0757134261658014 0.386191419897451 LRP5/KDM5B 2 GO:0106030 neuron projection fasciculation 2/389 22/18722 0.0757134261658014 0.386191419897451 EPHB3/NRP1 2 GO:0046546 development of primary male sexual characteristics 6/389 142/18722 0.0761429196838273 0.387298783942703 ASPM/LRP2/CTSV/ACVR2A/MMP14/ADGRG1 6 GO:2000045 regulation of G1/S transition of mitotic cell cycle 6/389 142/18722 0.0761429196838273 0.387298783942703 ADAMTS1/DCUN1D3/ANKRD17/EZH2/EGFR/ECD 6 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 9/389 249/18722 0.076523903260919 0.388694533694389 ZDHHC13/GJA1/WLS/SLC44A2/TFRC/ABL1/TRIM27/ANKRD17/IRAK4 9 GO:0008544 epidermis development 11/389 324/18722 0.0766569739677415 0.388828906898961 LGR5/PRKCH/PLOD1/FZD3/YAP1/SVEP1/FGFR2/ESRP1/LAMA5/EZH2/EGFR 11 GO:0043405 regulation of MAP kinase activity 7/389 177/18722 0.0767779635059849 0.388901712369898 FZD5/PPARG/HGS/HMGCR/TRIB1/EZH2/EGFR 7 GO:0043583 ear development 8/389 213/18722 0.077295849270059 0.39098191718156 LGR5/CYTL1/FZD3/GLI3/FGFR2/ESRP1/CEBPA/AHI1 8 GO:0042149 cellular response to glucose starvation 3/389 48/18722 0.0776244416066603 0.391017042181616 SIK2/SLC2A1/XBP1 3 GO:0042908 xenobiotic transport 3/389 48/18722 0.0776244416066603 0.391017042181616 ATP7B/GJA1/SLC2A1 3 GO:1903053 regulation of extracellular matrix organization 3/389 48/18722 0.0776244416066603 0.391017042181616 DAG1/LRP1/ABL1 3 GO:0000082 G1/S transition of mitotic cell cycle 8/389 214/18722 0.0789268592384054 0.39701942559782 ADAMTS1/DCUN1D3/ANKRD17/EZH2/CUL2/EGFR/ECD/SKP2 8 GO:0034599 cellular response to oxidative stress 10/389 288/18722 0.0790745380011694 0.39701942559782 MET/SLC7A11/PDK2/STK25/ABL1/SIGMAR1/AIFM2/PCNA/EZH2/EGFR 10 GO:0090559 regulation of membrane permeability 4/389 78/18722 0.0792384529760997 0.39701942559782 JAM3/CLDN3/TJP2/SLC25A4 4 GO:0051235 maintenance of location 11/389 326/18722 0.0792514784302751 0.39701942559782 ASPM/LTBP1/ATP7B/CDS1/PPARG/GJA1/FBN2/ABL1/CHERP/DMD/ITGAV 11 GO:0009063 cellular amino acid catabolic process 5/389 110/18722 0.0793964991481106 0.397200318783483 BCKDHB/BLMH/ENOSF1/GLDC/SHMT1 5 GO:0030857 negative regulation of epithelial cell differentiation 3/389 49/18722 0.0814707931747716 0.400540754108136 SPRED2/YAP1/EZH2 3 GO:0038084 vascular endothelial growth factor signaling pathway 3/389 49/18722 0.0814707931747716 0.400540754108136 SEMA6A/NRP1/MYO1C 3 GO:0045778 positive regulation of ossification 3/389 49/18722 0.0814707931747716 0.400540754108136 ACVR2A/FBN2/ANO6 3 GO:0070169 positive regulation of biomineral tissue development 3/389 49/18722 0.0814707931747716 0.400540754108136 ACVR2A/FBN2/ANO6 3 GO:0070741 response to interleukin-6 3/389 49/18722 0.0814707931747716 0.400540754108136 YAP1/CEBPA/IL6ST 3 GO:0072091 regulation of stem cell proliferation 3/389 49/18722 0.0814707931747716 0.400540754108136 GJA1/YAP1/FERMT2 3 GO:1904752 regulation of vascular associated smooth muscle cell migration 3/389 49/18722 0.0814707931747716 0.400540754108136 ADAMTS1/LRP1/DOCK5 3 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 5/389 111/18722 0.0818032172219752 0.400540754108136 PLXNB1/SERPINE2/ERBB3/PTK2/EGFR 5 GO:0006622 protein targeting to lysosome 2/389 23/18722 0.0818214592296576 0.400540754108136 HGS/SCARB2 2 GO:0010888 negative regulation of lipid storage 2/389 23/18722 0.0818214592296576 0.400540754108136 PPARG/ITGAV 2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules 2/389 23/18722 0.0818214592296576 0.400540754108136 CLDN4/CLDN3 2 GO:0021544 subpallium development 2/389 23/18722 0.0818214592296576 0.400540754108136 SLC7A11/GLI3 2 GO:0021871 forebrain regionalization 2/389 23/18722 0.0818214592296576 0.400540754108136 GLI3/ADGRG1 2 GO:0035994 response to muscle stretch 2/389 23/18722 0.0818214592296576 0.400540754108136 DMD/PTK2 2 GO:0042438 melanin biosynthetic process 2/389 23/18722 0.0818214592296576 0.400540754108136 SLC7A11/RAPGEF2 2 GO:0051383 kinetochore organization 2/389 23/18722 0.0818214592296576 0.400540754108136 CENPE/SMC2 2 GO:0008154 actin polymerization or depolymerization 8/389 217/18722 0.083942514931961 0.410373125947536 COBL/WASF1/CDC42EP4/KANK4/TRIM27/CYFIP1/MYO1C/LIMA1 8 GO:0042542 response to hydrogen peroxide 6/389 146/18722 0.0844099233817359 0.412105743739211 MET/STK25/ABL1/SIGMAR1/PCNA/EZH2 6 GO:0001570 vasculogenesis 4/389 80/18722 0.0851497344323096 0.412511570013299 EGFL7/YAP1/RAPGEF2/ITGAV 4 GO:0007422 peripheral nervous system development 4/389 80/18722 0.0851497344323096 0.412511570013299 ITGB4/DAG1/ERBB3/GPC1 4 GO:0071229 cellular response to acid chemical 4/389 80/18722 0.0851497344323096 0.412511570013299 COL4A1/DNMT3A/SLC38A9/XBP1 4 GO:0007632 visual behavior 3/389 50/18722 0.0853979257910723 0.412511570013299 SLC7A11/MEIS2/HMGCR 3 GO:0018023 peptidyl-lysine trimethylation 3/389 50/18722 0.0853979257910723 0.412511570013299 METTL21C/SUV39H1/SETD4 3 GO:0060425 lung morphogenesis 3/389 50/18722 0.0853979257910723 0.412511570013299 DAG1/YAP1/FGFR2 3 GO:0110151 positive regulation of biomineralization 3/389 50/18722 0.0853979257910723 0.412511570013299 ACVR2A/FBN2/ANO6 3 GO:1904738 vascular associated smooth muscle cell migration 3/389 50/18722 0.0853979257910723 0.412511570013299 ADAMTS1/LRP1/DOCK5 3 GO:0090596 sensory organ morphogenesis 9/389 256/18722 0.0872976350974231 0.418758924513375 FZD5/LRP5/FZD3/GLI3/FBN2/FGFR2/FAT1/TENM3/AHI1 9 GO:0051604 protein maturation 10/389 294/18722 0.0877437951516987 0.418758924513375 PLAU/GAS1/GLI3/MMP14/CLN3/LIPT2/MAGEF1/SERPINE2/LIPT1/SPRTN 10 GO:0001702 gastrulation with mouth forming second 2/389 24/18722 0.0880749704376043 0.418758924513375 LRP5/ACVR2A 2 GO:0006582 melanin metabolic process 2/389 24/18722 0.0880749704376043 0.418758924513375 SLC7A11/RAPGEF2 2 GO:0010226 response to lithium ion 2/389 24/18722 0.0880749704376043 0.418758924513375 CDH1/CEBPA 2 GO:0031639 plasminogen activation 2/389 24/18722 0.0880749704376043 0.418758924513375 PLAU/SERPINE2 2 GO:0036010 protein localization to endosome 2/389 24/18722 0.0880749704376043 0.418758924513375 NRP1/MICALL1 2 GO:0048011 neurotrophin TRK receptor signaling pathway 2/389 24/18722 0.0880749704376043 0.418758924513375 WASF1/CYFIP1 2 GO:0060561 apoptotic process involved in morphogenesis 2/389 24/18722 0.0880749704376043 0.418758924513375 FZD5/LRP5 2 GO:0061162 establishment of monopolar cell polarity 2/389 24/18722 0.0880749704376043 0.418758924513375 MYO9A/FAT1 2 GO:0014032 neural crest cell development 4/389 81/18722 0.0881839468127975 0.418758924513375 SEMA4G/SEMA6A/NRP1/LAMA5 4 GO:0071260 cellular response to mechanical stimulus 4/389 81/18722 0.0881839468127975 0.418758924513375 GJA1/DAG1/SLC2A1/EGFR 4 GO:1903533 regulation of protein targeting 4/389 81/18722 0.0881839468127975 0.418758924513375 FZD5/MIEF2/TCAF1/MYO1C 4 GO:0010212 response to ionizing radiation 6/389 148/18722 0.0887225804571164 0.41967736825824 ELK1/DNMT3A/DCUN1D3/YAP1/BLM/AEN 6 GO:0050905 neuromuscular process 6/389 148/18722 0.0887225804571164 0.41967736825824 SLC1A3/RAC3/ABL1/CLN3/RBFOX2/DMD 6 GO:0070507 regulation of microtubule cytoskeleton organization 6/389 148/18722 0.0887225804571164 0.41967736825824 MET/ABL1/ARL3/CLIP1/DYNC1H1/FKBP4 6 GO:0007041 lysosomal transport 5/389 114/18722 0.0892532286428767 0.420718493907057 LRP1/HGS/RAB7B/SCARB2/CLN3 5 GO:0046660 female sex differentiation 5/389 114/18722 0.0892532286428767 0.420718493907057 LRP2/ADAMTS1/NR2F2/ZFX/MMP14 5 GO:0045668 negative regulation of osteoblast differentiation 3/389 51/18722 0.0894041219572166 0.420718493907057 BAMBI/PPARG/LRP5 3 GO:0060043 regulation of cardiac muscle cell proliferation 3/389 51/18722 0.0894041219572166 0.420718493907057 GJA1/YAP1/FGFR2 3 GO:0007051 spindle organization 7/389 184/18722 0.0898754696935048 0.422391543778623 ASPM/MAP10/CENPE/TACC2/KIF11/RACGAP1/DYNC1H1 7 GO:0042593 glucose homeostasis 9/389 258/18722 0.0905337415544018 0.424937651800391 UNC13B/PPARG/LRP5/LRP1/PDK2/HMGCR/CEBPA/SLC16A1/XBP1 9 GO:0033500 carbohydrate homeostasis 9/389 259/18722 0.092178061523965 0.431544788675097 UNC13B/PPARG/LRP5/LRP1/PDK2/HMGCR/CEBPA/SLC16A1/XBP1 9 GO:0045927 positive regulation of growth 9/389 259/18722 0.092178061523965 0.431544788675097 SYT1/LRP1/TFCP2L1/YAP1/NRP1/MMP14/FGFR2/CYFIP1/EGFR 9 GO:0043434 response to peptide hormone 13/389 414/18722 0.0925735873193822 0.432840862761265 ECHDC3/PPARG/LRP5/GJA1/DAG1/PDK2/SIK2/CYFIP1/MYO1C/PTK2/SLC2A1/XBP1/SHC1 13 GO:0000302 response to reactive oxygen species 8/389 222/18722 0.0927096851321748 0.432922178843843 MET/PDK2/STK25/ABL1/SIGMAR1/PCNA/EZH2/EGFR 8 GO:0043277 apoptotic cell clearance 3/389 52/18722 0.0934876326092211 0.433076841217246 LRP1/XKR8/ITGAV 3 GO:0045010 actin nucleation 3/389 52/18722 0.0934876326092211 0.433076841217246 WASF1/TRIM27/CYFIP1 3 GO:0048511 rhythmic process 10/389 298/18722 0.093830671160024 0.433076841217246 ID4/ADAMTS1/PPARG/CLDN4/KDM5B/SUV39H1/PCNA/EZH2/BHLHE41/EGFR 10 GO:0120032 regulation of plasma membrane bounded cell projection assembly 7/389 186/18722 0.0938354522020187 0.433076841217246 DCDC2/COBL/CDC42EP4/YAP1/NRP1/CLN3/CYFIP1 7 GO:0090150 establishment of protein localization to membrane 9/389 260/18722 0.0938398685329415 0.433076841217246 ARL6/CLN3/EMC1/MICALL1/ICMT/MIEF2/TCAF1/MYO1C/EGFR 9 GO:0043200 response to amino acid 5/389 116/18722 0.0944091046285248 0.433076841217246 COL4A1/DNMT3A/SLC38A9/PCNA/XBP1 5 GO:0010996 response to auditory stimulus 2/389 25/18722 0.0944653145559919 0.433076841217246 SLC1A3/ABHD12 2 GO:0021846 cell proliferation in forebrain 2/389 25/18722 0.0944653145559919 0.433076841217246 GLI3/FGFR2 2 GO:0033622 integrin activation 2/389 25/18722 0.0944653145559919 0.433076841217246 JAM3/FERMT2 2 GO:0044550 secondary metabolite biosynthetic process 2/389 25/18722 0.0944653145559919 0.433076841217246 SLC7A11/RAPGEF2 2 GO:0048143 astrocyte activation 2/389 25/18722 0.0944653145559919 0.433076841217246 LRP1/EGFR 2 GO:0061339 establishment or maintenance of monopolar cell polarity 2/389 25/18722 0.0944653145559919 0.433076841217246 MYO9A/FAT1 2 GO:0090330 regulation of platelet aggregation 2/389 25/18722 0.0944653145559919 0.433076841217246 SERPINE2/IL6ST 2 GO:1900078 positive regulation of cellular response to insulin stimulus 2/389 25/18722 0.0944653145559919 0.433076841217246 ECHDC3/MYO1C 2 GO:0050920 regulation of chemotaxis 8/389 223/18722 0.0945240377320888 0.433076841217246 MET/SEMA4G/SEMA6A/JAM3/NRP1/TPBG/PTK2/ANO6 8 GO:0006261 DNA-dependent DNA replication 6/389 151/18722 0.0954130854752653 0.436601659633993 MCM10/WRNIP1/PCNA/POLA2/BLM/MCM5 6 GO:0008064 regulation of actin polymerization or depolymerization 7/389 187/18722 0.0958514486446995 0.437509678607283 WASF1/CDC42EP4/KANK4/TRIM27/CYFIP1/MYO1C/LIMA1 7 GO:0061136 regulation of proteasomal protein catabolic process 7/389 187/18722 0.0958514486446995 0.437509678607283 RHBDF1/TMTC3/USP5/FZR1/TRIB1/CEBPA/RNF19B 7 GO:0051225 spindle assembly 5/389 117/18722 0.0970430281369491 0.440752770276324 ASPM/MAP10/KIF11/RACGAP1/DYNC1H1 5 GO:0009636 response to toxic substance 9/389 262/18722 0.0972158535290117 0.440752770276324 TXNRD3/SLC7A11/ATP7B/MPST/CDH1/DNMT3A/BLMH/KDM5B/MT1A 9 GO:0006970 response to osmotic stress 4/389 84/18722 0.0975939166666355 0.440752770276324 MARVELD3/CLN3/SLC2A1/EGFR 4 GO:0042310 vasoconstriction 4/389 84/18722 0.0975939166666355 0.440752770276324 GJA1/DOCK5/HMGCR/EGFR 4 GO:0042440 pigment metabolic process 4/389 84/18722 0.0975939166666355 0.440752770276324 SLC7A11/COX10/SHMT1/RAPGEF2 4 GO:0007566 embryo implantation 3/389 53/18722 0.0976466805530722 0.440752770276324 ITGB4/GJA1/PRLR 3 GO:0051438 regulation of ubiquitin-protein transferase activity 3/389 53/18722 0.0976466805530722 0.440752770276324 DCUN1D3/ABL1/FZR1 3 GO:1990090 cellular response to nerve growth factor stimulus 3/389 53/18722 0.0976466805530722 0.440752770276324 WASF1/MICALL1/RAPGEF2 3 GO:0006575 cellular modified amino acid metabolic process 7/389 188/18722 0.0978913473879414 0.440752770276324 SLC7A11/CPT1C/PCYOX1/SHMT1/ABHD12/GSTA4/MTHFD2L 7 GO:0030832 regulation of actin filament length 7/389 188/18722 0.0978913473879414 0.440752770276324 WASF1/CDC42EP4/KANK4/TRIM27/CYFIP1/MYO1C/LIMA1 7 GO:0060491 regulation of cell projection assembly 7/389 188/18722 0.0978913473879414 0.440752770276324 DCDC2/COBL/CDC42EP4/YAP1/NRP1/CLN3/CYFIP1 7 GO:0032868 response to insulin 9/389 264/18722 0.100661486777081 0.450231250338163 ECHDC3/PPARG/PDK2/SIK2/CYFIP1/MYO1C/SLC2A1/XBP1/SHC1 9 GO:0006760 folic acid-containing compound metabolic process 2/389 26/18722 0.100984141150704 0.450231250338163 SHMT1/MTHFD2L 2 GO:0010875 positive regulation of cholesterol efflux 2/389 26/18722 0.100984141150704 0.450231250338163 PPARG/LRP1 2 GO:0018027 peptidyl-lysine dimethylation 2/389 26/18722 0.100984141150704 0.450231250338163 SUV39H1/SETD4 2 GO:0021952 central nervous system projection neuron axonogenesis 2/389 26/18722 0.100984141150704 0.450231250338163 EPHB3/FBXO45 2 GO:0031167 rRNA methylation 2/389 26/18722 0.100984141150704 0.450231250338163 MRM1/NSUN4 2 GO:0046697 decidualization 2/389 26/18722 0.100984141150704 0.450231250338163 CTSV/GJA1 2 GO:1905523 positive regulation of macrophage migration 2/389 26/18722 0.100984141150704 0.450231250338163 MMP14/PTK2 2 GO:0050678 regulation of epithelial cell proliferation 12/389 381/18722 0.101491947401308 0.451942774325481 EGFL7/MARVELD3/PPARG/NR2F2/GJA1/YAP1/NRP1/KDM5B/LAMC1/FGFR2/EGFR/XBP1 12 GO:0030520 intracellular estrogen receptor signaling pathway 3/389 54/18722 0.10187946374356 0.452012657266134 YAP1/RBFOX2/SKP2 3 GO:0043647 inositol phosphate metabolic process 3/389 54/18722 0.10187946374356 0.452012657266134 SYNJ2/IPPK/INPP4A 3 GO:0070839 metal ion export 3/389 54/18722 0.10187946374356 0.452012657266134 SLC35G1/ATP7B/ANO6 3 GO:0030041 actin filament polymerization 7/389 190/18722 0.102042514920733 0.452167701304842 COBL/WASF1/CDC42EP4/KANK4/TRIM27/CYFIP1/MYO1C 7 GO:0007605 sensory perception of sound 6/389 154/18722 0.102366213953051 0.452167701304842 LRP2/DCDC2/SRRM4/SLC1A3/LRIG2/SCARB2 6 GO:0030856 regulation of epithelial cell differentiation 6/389 154/18722 0.102366213953051 0.452167701304842 PRKCH/SPRED2/YAP1/ESRP1/AHI1/EZH2 6 GO:0030522 intracellular receptor signaling pathway 9/389 265/18722 0.102410343097834 0.452167701304842 PPARG/NR2F2/DCBLD2/YAP1/TRIM24/RBFOX2/ANKRD17/EZH2/SKP2 9 GO:0009798 axis specification 4/389 86/18722 0.104117111176746 0.4569375504953 FZD5/COBL/WLS/AHI1 4 GO:0014031 mesenchymal cell development 4/389 86/18722 0.104117111176746 0.4569375504953 SEMA4G/SEMA6A/NRP1/LAMA5 4 GO:0015908 fatty acid transport 4/389 86/18722 0.104117111176746 0.4569375504953 SLC27A2/PPARG/SLC27A6/SLC2A1 4 GO:0035023 regulation of Rho protein signal transduction 4/389 86/18722 0.104117111176746 0.4569375504953 MET/NRP1/ABL1/ADGRG1 4 GO:0048864 stem cell development 4/389 86/18722 0.104117111176746 0.4569375504953 SEMA4G/SEMA6A/NRP1/LAMA5 4 GO:0051147 regulation of muscle cell differentiation 6/389 155/18722 0.104741575682719 0.45912563283038 MMP14/FGFR2/ANKRD17/EZH2/BHLHE41/XBP1 6 GO:0042326 negative regulation of phosphorylation 12/389 385/18722 0.107348616148667 0.465338140717836 EPHA1/SPRED2/PPARG/LRP5/NR2F2/LRP1/ABL1/HMGCR/TRIB1/TRIM27/CEBPA/DMD 12 GO:0001776 leukocyte homeostasis 4/389 87/18722 0.107451698620182 0.465338140717836 SLC7A11/JAM3/ABL1/XKR8 4 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 2/389 27/18722 0.107623386121152 0.465338140717836 ABL1/PTK2 2 GO:0003401 axis elongation 2/389 27/18722 0.107623386121152 0.465338140717836 YAP1/FGFR2 2 GO:0015813 L-glutamate transmembrane transport 2/389 27/18722 0.107623386121152 0.465338140717836 SLC7A11/SLC1A3 2 GO:0034453 microtubule anchoring 2/389 27/18722 0.107623386121152 0.465338140717836 DAG1/SAXO2 2 GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 2/389 27/18722 0.107623386121152 0.465338140717836 ABL1/PTK2 2 GO:0070861 regulation of protein exit from endoplasmic reticulum 2/389 27/18722 0.107623386121152 0.465338140717836 TMEM30B/TM9SF4 2 GO:1900746 regulation of vascular endothelial growth factor signaling pathway 2/389 27/18722 0.107623386121152 0.465338140717836 SEMA6A/MYO1C 2 GO:0051348 negative regulation of transferase activity 9/389 268/18722 0.107760624624176 0.465338140717836 EPHA1/PPARG/LRP5/NR2F2/ABL1/HMGCR/TRIB1/TRIM27/CEBPA 9 GO:0003206 cardiac chamber morphogenesis 5/389 121/18722 0.107945178790044 0.465338140717836 LRP2/ADAMTS1/NRP1/FGFR2/FHL2 5 GO:0038127 ERBB signaling pathway 5/389 121/18722 0.107945178790044 0.465338140717836 RHBDF1/ABL1/PTK2/EGFR/SHC1 5 GO:0045931 positive regulation of mitotic cell cycle 5/389 121/18722 0.107945178790044 0.465338140717836 ADAMTS1/MEIS2/ABL1/ANKRD17/EGFR 5 GO:1904019 epithelial cell apoptotic process 5/389 121/18722 0.107945178790044 0.465338140717836 DNMT3A/YAP1/ABL1/STK3/ANO6 5 GO:0007565 female pregnancy 7/389 193/18722 0.108446284626429 0.466946399093965 ITGB4/CTSV/NR2F2/GJA1/CLDN4/PRLR/SLC2A1 7 GO:0045860 positive regulation of protein kinase activity 12/389 386/18722 0.108843385617922 0.468103569986509 CENPE/FZD5/DAG1/ABL1/FERMT2/RAPGEF2/ERBB3/EZH2/STK3/PRLR/PTK2/EGFR 12 GO:0010332 response to gamma radiation 3/389 56/18722 0.110558922047639 0.47214097038377 ELK1/DCUN1D3/YAP1 3 GO:0015800 acidic amino acid transport 3/389 56/18722 0.110558922047639 0.47214097038377 SLC7A11/SLC1A3/GJA1 3 GO:0031529 ruffle organization 3/389 56/18722 0.110558922047639 0.47214097038377 COBL/CYFIP1/LIMA1 3 GO:0042733 embryonic digit morphogenesis 3/389 56/18722 0.110558922047639 0.47214097038377 LRP5/GLI3/CHST11 3 GO:0051653 spindle localization 3/389 56/18722 0.110558922047639 0.47214097038377 ASPM/GJA1/DYNC1H1 3 GO:1990089 response to nerve growth factor 3/389 56/18722 0.110558922047639 0.47214097038377 WASF1/MICALL1/RAPGEF2 3 GO:0031109 microtubule polymerization or depolymerization 5/389 122/18722 0.110760755523621 0.472449678824148 MET/ABL1/ARL3/CLIP1/FKBP4 5 GO:0001945 lymph vessel development 2/389 28/18722 0.114375263457362 0.483905552005798 NR2F2/SVEP1 2 GO:0010464 regulation of mesenchymal cell proliferation 2/389 28/18722 0.114375263457362 0.483905552005798 LRP5/FGFR2 2 GO:0015740 C4-dicarboxylate transport 2/389 28/18722 0.114375263457362 0.483905552005798 SLC1A3/SLC25A11 2 GO:0038094 Fc-gamma receptor signaling pathway 2/389 28/18722 0.114375263457362 0.483905552005798 ABL1/PTK2 2 GO:0044331 cell-cell adhesion mediated by cadherin 2/389 28/18722 0.114375263457362 0.483905552005798 TJP1/CTNND1 2 GO:0051503 adenine nucleotide transport 2/389 28/18722 0.114375263457362 0.483905552005798 GJA1/SLC25A4 2 GO:0090344 negative regulation of cell aging 2/389 28/18722 0.114375263457362 0.483905552005798 ABL1/FZR1 2 GO:0046488 phosphatidylinositol metabolic process 6/389 159/18722 0.114526655510986 0.483984603300773 SYNJ2/TTC7B/CDS1/MBOAT7/PIGV/INPP4A 6 GO:0050891 multicellular organismal water homeostasis 3/389 57/18722 0.115001896239793 0.485430457854774 MET/CLDN4/LSR 3 GO:0046942 carboxylic acid transport 9/389 273/18722 0.117020763189309 0.493381183065214 LRP2/SLC7A11/SLC1A3/GJA1/SLC38A9/CLN3/SLC26A2/SLC25A11/SLC16A1 9 GO:0030901 midbrain development 4/389 90/18722 0.117739031203006 0.494622571344467 NDRG2/WLS/FZD3/FGFR2 4 GO:0034109 homotypic cell-cell adhesion 4/389 90/18722 0.117739031203006 0.494622571344467 SLC7A11/TJP2/SERPINE2/IL6ST 4 GO:0046849 bone remodeling 4/389 90/18722 0.117739031203006 0.494622571344467 LRP5/GJA1/TFRC/EGFR 4 GO:0045930 negative regulation of mitotic cell cycle 8/389 235/18722 0.117857695228501 0.494622571344467 GAS1/FZD3/DCUN1D3/ABL1/FZR1/BLM/EZH2/EGFR 8 GO:0046486 glycerolipid metabolic process 12/389 392/18722 0.118067797861641 0.4949347802315 SYNJ2/TTC7B/SLC44A5/AGPAT4/CDS1/MBOAT7/SLC44A2/PIGV/CLN3/SERAC1/INPP4A/ABHD12 12 GO:0045604 regulation of epidermal cell differentiation 3/389 58/18722 0.119511209382747 0.499701795695964 PRKCH/ESRP1/EZH2 3 GO:0090068 positive regulation of cell cycle process 8/389 236/18722 0.11993026951565 0.499701795695964 MAP10/ADAMTS1/LRP5/RACGAP1/ANKRD17/DYNC1H1/EZH2/EGFR 8 GO:0010955 negative regulation of protein processing 2/389 29/18722 0.121232257214582 0.499701795695964 GAS1/SERPINE2 2 GO:0015868 purine ribonucleotide transport 2/389 29/18722 0.121232257214582 0.499701795695964 GJA1/SLC25A4 2 GO:0021602 cranial nerve morphogenesis 2/389 29/18722 0.121232257214582 0.499701795695964 GLI3/NRP1 2 GO:0022011 myelination in peripheral nervous system 2/389 29/18722 0.121232257214582 0.499701795695964 ITGB4/DAG1 2 GO:0032292 peripheral nervous system axon ensheathment 2/389 29/18722 0.121232257214582 0.499701795695964 ITGB4/DAG1 2 GO:0048665 neuron fate specification 2/389 29/18722 0.121232257214582 0.499701795695964 GLI3/ESRP1 2 GO:0048679 regulation of axon regeneration 2/389 29/18722 0.121232257214582 0.499701795695964 LRP1/LRIG2 2 GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus 2/389 29/18722 0.121232257214582 0.499701795695964 SEMA6A/MYO1C 2 GO:1903318 negative regulation of protein maturation 2/389 29/18722 0.121232257214582 0.499701795695964 GAS1/SERPINE2 2 GO:0006885 regulation of pH 4/389 91/18722 0.121260238330389 0.499701795695964 PDK2/CLN3/TMEM175/TM9SF4 4 GO:0014033 neural crest cell differentiation 4/389 91/18722 0.121260238330389 0.499701795695964 SEMA4G/SEMA6A/NRP1/LAMA5 4 GO:0060191 regulation of lipase activity 4/389 91/18722 0.121260238330389 0.499701795695964 LRP1/ABL1/FGFR2/EGFR 4 GO:0072080 nephron tubule development 4/389 91/18722 0.121260238330389 0.499701795695964 GLI3/YAP1/LAMA5/AHI1 4 GO:0007548 sex differentiation 9/389 276/18722 0.122780289767595 0.505394714201374 ASPM/LRP2/ADAMTS1/CTSV/ACVR2A/NR2F2/ZFX/MMP14/ADGRG1 9 GO:0048010 vascular endothelial growth factor receptor signaling pathway 3/389 59/18722 0.124084979251363 0.509614774019958 HGS/NRP1/PTK2 3 GO:0048278 vesicle docking 3/389 59/18722 0.124084979251363 0.509614774019958 UNC13B/SYT1/CLN3 3 GO:0043414 macromolecule methylation 10/389 316/18722 0.124237542170139 0.509667397406634 METTL21C/DNMT3A/MRM1/ICMT/SUV39H1/EZH2/SETD4/HELLS/WDR5/NSUN4 10 GO:0061025 membrane fusion 6/389 163/18722 0.124756135542187 0.511219804856579 SYT1/RAB7B/HACE1/CLN3/TMEM175/MYOF 6 GO:0006884 cell volume homeostasis 2/389 30/18722 0.128187113699956 0.515309151972943 CLN3/ANO6 2 GO:0015865 purine nucleotide transport 2/389 30/18722 0.128187113699956 0.515309151972943 GJA1/SLC25A4 2 GO:0030204 chondroitin sulfate metabolic process 2/389 30/18722 0.128187113699956 0.515309151972943 CHPF/CHST11 2 GO:0034508 centromere complex assembly 2/389 30/18722 0.128187113699956 0.515309151972943 CENPE/HELLS 2 GO:0045577 regulation of B cell differentiation 2/389 30/18722 0.128187113699956 0.515309151972943 MMP14/XBP1 2 GO:0051125 regulation of actin nucleation 2/389 30/18722 0.128187113699956 0.515309151972943 WASF1/CYFIP1 2 GO:0061384 heart trabecula morphogenesis 2/389 30/18722 0.128187113699956 0.515309151972943 ADAMTS1/FHL2 2 GO:2000648 positive regulation of stem cell proliferation 2/389 30/18722 0.128187113699956 0.515309151972943 GJA1/FERMT2 2 GO:0033865 nucleoside bisphosphate metabolic process 5/389 128/18722 0.12838366880884 0.515309151972943 PDK2/SLC26A2/HMGCR/ACSF2/COASY 5 GO:0033875 ribonucleoside bisphosphate metabolic process 5/389 128/18722 0.12838366880884 0.515309151972943 PDK2/SLC26A2/HMGCR/ACSF2/COASY 5 GO:0034032 purine nucleoside bisphosphate metabolic process 5/389 128/18722 0.12838366880884 0.515309151972943 PDK2/SLC26A2/HMGCR/ACSF2/COASY 5 GO:0016054 organic acid catabolic process 8/389 240/18722 0.128412924303888 0.515309151972943 CPT1C/SLC27A2/MPST/BCKDHB/BLMH/ENOSF1/GLDC/SHMT1 8 GO:0070085 glycosylation 8/389 240/18722 0.128412924303888 0.515309151972943 UGGT2/PMM1/GCNT2/PIGV/TMTC2/TMTC3/GALNT11/EXTL2 8 GO:0060349 bone morphogenesis 4/389 93/18722 0.128436270594035 0.515309151972943 LRP5/GLI3/MMP14/FGFR2 4 GO:0097306 cellular response to alcohol 4/389 93/18722 0.128436270594035 0.515309151972943 DAG1/CDH1/DNMT3A/BLM 4 GO:0031638 zymogen activation 3/389 60/18722 0.128721315450329 0.515309151972943 PLAU/MMP14/SERPINE2 3 GO:0033866 nucleoside bisphosphate biosynthetic process 3/389 60/18722 0.128721315450329 0.515309151972943 PDK2/SLC26A2/COASY 3 GO:0034030 ribonucleoside bisphosphate biosynthetic process 3/389 60/18722 0.128721315450329 0.515309151972943 PDK2/SLC26A2/COASY 3 GO:0034033 purine nucleoside bisphosphate biosynthetic process 3/389 60/18722 0.128721315450329 0.515309151972943 PDK2/SLC26A2/COASY 3 GO:0042306 regulation of protein import into nucleus 3/389 60/18722 0.128721315450329 0.515309151972943 CDH1/GLI3/NUP58 3 GO:0060038 cardiac muscle cell proliferation 3/389 60/18722 0.128721315450329 0.515309151972943 GJA1/YAP1/FGFR2 3 GO:1901653 cellular response to peptide 11/389 359/18722 0.129918265510936 0.518285380623224 ECHDC3/PPARG/GJA1/LRP1/PDK2/SIK2/CYFIP1/MYO1C/PTK2/XBP1/SHC1 11 GO:0046661 male sex differentiation 6/389 165/18722 0.130033211754936 0.518285380623224 ASPM/LRP2/CTSV/ACVR2A/MMP14/ADGRG1 6 GO:0071772 response to BMP 6/389 165/18722 0.130033211754936 0.518285380623224 LRP2/BAMBI/PPARG/ACVR2A/ABL1/SPINT1 6 GO:0071773 cellular response to BMP stimulus 6/389 165/18722 0.130033211754936 0.518285380623224 LRP2/BAMBI/PPARG/ACVR2A/ABL1/SPINT1 6 GO:0044843 cell cycle G1/S phase transition 8/389 241/18722 0.130581179061478 0.519901266416168 ADAMTS1/DCUN1D3/ANKRD17/EZH2/CUL2/EGFR/ECD/SKP2 8 GO:0071496 cellular response to external stimulus 10/389 320/18722 0.131652459877239 0.523594897679707 CTSV/GJA1/DAG1/PDK2/TRIM24/SIK2/SLC2A1/EGFR/SKP2/XBP1 10 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 4/389 94/18722 0.132089539080422 0.524760946651742 NR2F2/BLM/CEBPA/EGFR 4 GO:0030307 positive regulation of cell growth 6/389 166/18722 0.132711513645286 0.526658204857844 SYT1/LRP1/NRP1/MMP14/CYFIP1/EGFR 6 GO:0030865 cortical cytoskeleton organization 3/389 61/18722 0.133418321742239 0.527480369100687 RAC3/RACGAP1/EPB41L3 3 GO:0034113 heterotypic cell-cell adhesion 3/389 61/18722 0.133418321742239 0.527480369100687 JAM3/GCNT2/ITGAV 3 GO:0043954 cellular component maintenance 3/389 61/18722 0.133418321742239 0.527480369100687 TJP1/CLDN3/FERMT2 3 GO:0033238 regulation of cellular amine metabolic process 2/389 31/18722 0.135232833865956 0.527480369100687 SLC7A11/CLN3 2 GO:0048384 retinoic acid receptor signaling pathway 2/389 31/18722 0.135232833865956 0.527480369100687 PPARG/EZH2 2 GO:0048566 embryonic digestive tract development 2/389 31/18722 0.135232833865956 0.527480369100687 GLI3/FGFR2 2 GO:0048710 regulation of astrocyte differentiation 2/389 31/18722 0.135232833865956 0.527480369100687 SERPINE2/IL6ST 2 GO:0051443 positive regulation of ubiquitin-protein transferase activity 2/389 31/18722 0.135232833865956 0.527480369100687 DCUN1D3/FZR1 2 GO:0060045 positive regulation of cardiac muscle cell proliferation 2/389 31/18722 0.135232833865956 0.527480369100687 YAP1/FGFR2 2 GO:0060055 angiogenesis involved in wound healing 2/389 31/18722 0.135232833865956 0.527480369100687 DAG1/XBP1 2 GO:0070633 transepithelial transport 2/389 31/18722 0.135232833865956 0.527480369100687 SLC1A3/CLDN3 2 GO:0070723 response to cholesterol 2/389 31/18722 0.135232833865956 0.527480369100687 DAG1/HMGCR 2 GO:0071480 cellular response to gamma radiation 2/389 31/18722 0.135232833865956 0.527480369100687 ELK1/YAP1 2 GO:0071711 basement membrane organization 2/389 31/18722 0.135232833865956 0.527480369100687 COL4A1/DAG1 2 GO:0090162 establishment of epithelial cell polarity 2/389 31/18722 0.135232833865956 0.527480369100687 MYO9A/FAT1 2 GO:1900027 regulation of ruffle assembly 2/389 31/18722 0.135232833865956 0.527480369100687 COBL/CYFIP1 2 GO:0008585 female gonad development 4/389 95/18722 0.135785250745558 0.528504599219904 ADAMTS1/NR2F2/ZFX/MMP14 4 GO:0036473 cell death in response to oxidative stress 4/389 95/18722 0.135785250745558 0.528504599219904 MET/SLC7A11/STK25/SIGMAR1 4 GO:0060348 bone development 7/389 205/18722 0.136125734111881 0.529264981136493 LRP5/GJA1/GLI3/MMP14/FGFR2/PLXNB1/P3H1 7 GO:0018022 peptidyl-lysine methylation 5/389 131/18722 0.137646717965891 0.533249668095445 METTL21C/SUV39H1/EZH2/SETD4/WDR5 5 GO:1902806 regulation of cell cycle G1/S phase transition 6/389 168/18722 0.138146401061876 0.533249668095445 ADAMTS1/DCUN1D3/ANKRD17/EZH2/EGFR/ECD 6 GO:0010573 vascular endothelial growth factor production 3/389 62/18722 0.138174098258897 0.533249668095445 NDRG2/IL6ST/ADGRG1 3 GO:0046847 filopodium assembly 3/389 62/18722 0.138174098258897 0.533249668095445 ITGB4/NRP1/CLN3 3 GO:0060135 maternal process involved in female pregnancy 3/389 62/18722 0.138174098258897 0.533249668095445 CTSV/NR2F2/GJA1 3 GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 3/389 62/18722 0.138174098258897 0.533249668095445 PPARG/ACVR2A/LRP1 3 GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 3/389 62/18722 0.138174098258897 0.533249668095445 CPT1C/DAG1/CTNND1 3 GO:0048863 stem cell differentiation 7/389 206/18722 0.138576601760938 0.534237702560403 SEMA4G/SEMA6A/YAP1/NRP1/ABL1/FGFR2/LAMA5 7 GO:0032259 methylation 11/389 364/18722 0.138865429792347 0.53478587376208 METTL21C/NSUN7/DNMT3A/MRM1/ICMT/SUV39H1/EZH2/SETD4/HELLS/WDR5/NSUN4 11 GO:0030510 regulation of BMP signaling pathway 4/389 96/18722 0.139522597513436 0.536435904323238 LRP2/BAMBI/PPARG/ABL1 4 GO:0006979 response to oxidative stress 13/389 446/18722 0.139588065040514 0.536435904323238 MET/SLC7A11/PDK2/C19orf12/STK25/SCARA3/ABL1/MMP14/SIGMAR1/AIFM2/PCNA/EZH2/EGFR 13 GO:0014044 Schwann cell development 2/389 32/18722 0.142362665905391 0.541958917074073 ITGB4/DAG1 2 GO:0035767 endothelial cell chemotaxis 2/389 32/18722 0.142362665905391 0.541958917074073 MET/NRP1 2 GO:0042219 cellular modified amino acid catabolic process 2/389 32/18722 0.142362665905391 0.541958917074073 PCYOX1/ABHD12 2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity 2/389 32/18722 0.142362665905391 0.541958917074073 NR2F2/CEBPA 2 GO:0045879 negative regulation of smoothened signaling pathway 2/389 32/18722 0.142362665905391 0.541958917074073 GLI3/SERPINE2 2 GO:0051497 negative regulation of stress fiber assembly 2/389 32/18722 0.142362665905391 0.541958917074073 MET/TJP1 2 GO:0061036 positive regulation of cartilage development 2/389 32/18722 0.142362665905391 0.541958917074073 GLI3/ZNF219 2 GO:0090140 regulation of mitochondrial fission 2/389 32/18722 0.142362665905391 0.541958917074073 PPARG/MIEF2 2 GO:1901889 negative regulation of cell junction assembly 2/389 32/18722 0.142362665905391 0.541958917074073 LRP1/MMP14 2 GO:1904589 regulation of protein import 3/389 63/18722 0.142986743600139 0.543767105223887 CDH1/GLI3/NUP58 3 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 4/389 97/18722 0.14330076081027 0.544393619453182 ITGA6/YAP1/NRP1/ITGAV 4 GO:0007517 muscle organ development 10/389 327/18722 0.14518546938742 0.550979611712719 LRP2/NR2F2/DAG1/FGFR2/HMGCR/LAMA5/DMD/SGCB/XBP1/GPC1 10 GO:0030833 regulation of actin filament polymerization 6/389 171/18722 0.146490527830833 0.554777731047817 WASF1/CDC42EP4/KANK4/TRIM27/CYFIP1/MYO1C 6 GO:0048469 cell maturation 6/389 171/18722 0.146490527830833 0.554777731047817 SRRM4/FZD5/PPARG/TFCP2L1/RAC3/CEBPA 6 GO:1904029 regulation of cyclin-dependent protein kinase activity 4/389 98/18722 0.147118912321235 0.555717734395901 NR2F2/BLM/CEBPA/EGFR 4 GO:0009896 positive regulation of catabolic process 14/389 492/18722 0.147125013586722 0.555717734395901 LRP2/GJA1/LRP1/HACE1/TMTC3/USP5/MAGEF1/FZR1/TRIB1/TRIM27/CEBPA/SLC25A4/PTK2/RNF19B 14 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 5/389 134/18722 0.147195868227705 0.555717734395901 USP5/FZR1/TRIB1/CEBPA/RNF19B 5 GO:0046854 phosphatidylinositol phosphate biosynthetic process 3/389 64/18722 0.147854356824358 0.556475582392605 SYNJ2/TTC7B/INPP4A 3 GO:0046888 negative regulation of hormone secretion 3/389 64/18722 0.147854356824358 0.556475582392605 GJA1/RAB11FIP3/HMGCR 3 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 3/389 64/18722 0.147854356824358 0.556475582392605 LRP5/LRP1/HMGCR 3 GO:0007623 circadian rhythm 7/389 210/18722 0.148592743261982 0.557182990360129 ID4/PPARG/CLDN4/SUV39H1/EZH2/BHLHE41/EGFR 7 GO:0046883 regulation of hormone secretion 8/389 249/18722 0.1485951109709 0.557182990360129 LRP5/GJA1/LRP1/KDM5B/RAB11FIP3/HMGCR/SLC16A1/EGFR 8 GO:0002431 Fc receptor mediated stimulatory signaling pathway 2/389 33/18722 0.14957009804293 0.557182990360129 ABL1/PTK2 2 GO:0010259 multicellular organism aging 2/389 33/18722 0.14957009804293 0.557182990360129 CTSV/TFCP2L1 2 GO:0034110 regulation of homotypic cell-cell adhesion 2/389 33/18722 0.14957009804293 0.557182990360129 SERPINE2/IL6ST 2 GO:0042558 pteridine-containing compound metabolic process 2/389 33/18722 0.14957009804293 0.557182990360129 SHMT1/MTHFD2L 2 GO:0048048 embryonic eye morphogenesis 2/389 33/18722 0.14957009804293 0.557182990360129 FZD5/FBN2 2 GO:0070570 regulation of neuron projection regeneration 2/389 33/18722 0.14957009804293 0.557182990360129 LRP1/LRIG2 2 GO:1903146 regulation of autophagy of mitochondrion 2/389 33/18722 0.14957009804293 0.557182990360129 FZD5/SLC25A4 2 GO:1904030 negative regulation of cyclin-dependent protein kinase activity 2/389 33/18722 0.14957009804293 0.557182990360129 NR2F2/CEBPA 2 GO:0001101 response to acid chemical 5/389 135/18722 0.150440429598663 0.559282616459047 COL4A1/DNMT3A/SLC38A9/PCNA/XBP1 5 GO:0042157 lipoprotein metabolic process 5/389 135/18722 0.150440429598663 0.559282616459047 ZDHHC13/LRP1/PIGV/ABHD12/ITGAV 5 GO:0051153 regulation of striated muscle cell differentiation 4/389 99/18722 0.150976214732403 0.560203781518097 MMP14/EZH2/BHLHE41/XBP1 4 GO:0042180 cellular ketone metabolic process 7/389 211/18722 0.151149032359147 0.560203781518097 SLC7A11/PPARG/PDK2/CLN3/AIFM2/HMGCR/COQ9 7 GO:0050807 regulation of synapse organization 7/389 211/18722 0.151149032359147 0.560203781518097 EPHB3/SLC7A11/DAG1/TPBG/ABL1/CLN3/CYFIP1 7 GO:0034504 protein localization to nucleus 9/389 290/18722 0.151613899685174 0.56021873571614 POLR1A/RGPD5/PYGO1/CDH1/GLI3/TFRC/YAP1/FERMT2/NUP58 9 GO:0044403 biological process involved in symbiotic interaction 9/389 290/18722 0.151613899685174 0.56021873571614 DAG1/SCARB2/TFRC/NRP1/ITGB5/TRIM27/ITGAV/EGFR/ANO6 9 GO:0071375 cellular response to peptide hormone stimulus 9/389 290/18722 0.151613899685174 0.56021873571614 ECHDC3/PPARG/PDK2/SIK2/CYFIP1/MYO1C/PTK2/XBP1/SHC1 9 GO:0045682 regulation of epidermis development 3/389 65/18722 0.152775039334764 0.561098256247618 PRKCH/ESRP1/EZH2 3 GO:0048645 animal organ formation 3/389 65/18722 0.152775039334764 0.561098256247618 LRP2/GLI3/FGFR2 3 GO:0060389 pathway-restricted SMAD protein phosphorylation 3/389 65/18722 0.152775039334764 0.561098256247618 PPARG/ACVR2A/LRP1 3 GO:0061512 protein localization to cilium 3/389 65/18722 0.152775039334764 0.561098256247618 ARL6/RAB11FIP3/ARL3 3 GO:0090307 mitotic spindle assembly 3/389 65/18722 0.152775039334764 0.561098256247618 MAP10/KIF11/RACGAP1 3 GO:1902475 L-alpha-amino acid transmembrane transport 3/389 65/18722 0.152775039334764 0.561098256247618 SLC7A11/SLC1A3/SLC38A9 3 GO:0072073 kidney epithelium development 5/389 136/18722 0.153714983444596 0.563455427095185 GLI3/YAP1/FGFR2/LAMA5/AHI1 5 GO:0009749 response to glucose 7/389 212/18722 0.153725843147713 0.563455427095185 UNC13B/CTSV/LRP5/GJA1/LRP1/HMGCR/XBP1 7 GO:0044728 DNA methylation or demethylation 4/389 100/18722 0.154871822457682 0.565382919422588 DNMT3A/TDG/EZH2/HELLS 4 GO:0045807 positive regulation of endocytosis 4/389 100/18722 0.154871822457682 0.565382919422588 LRP1/CLN3/AHI1/ANO6 4 GO:0046545 development of primary female sexual characteristics 4/389 100/18722 0.154871822457682 0.565382919422588 ADAMTS1/NR2F2/ZFX/MMP14 4 GO:0060840 artery development 4/389 100/18722 0.154871822457682 0.565382919422588 LRP2/GLI3/LRP1/NRP1 4 GO:0048639 positive regulation of developmental growth 6/389 174/18722 0.15505823879083 0.565497396870155 SYT1/LRP1/YAP1/NRP1/FGFR2/CYFIP1 6 GO:0000038 very long-chain fatty acid metabolic process 2/389 34/18722 0.156848851518205 0.567540651210662 SLC27A2/SLC27A6 2 GO:0007095 mitotic G2 DNA damage checkpoint signaling 2/389 34/18722 0.156848851518205 0.567540651210662 FZR1/BLM 2 GO:0010661 positive regulation of muscle cell apoptotic process 2/389 34/18722 0.156848851518205 0.567540651210662 PPARG/HMGCR 2 GO:0030851 granulocyte differentiation 2/389 34/18722 0.156848851518205 0.567540651210662 TRIB1/CEBPA 2 GO:0070884 regulation of calcineurin-NFAT signaling cascade 2/389 34/18722 0.156848851518205 0.567540651210662 CHERP/FHL2 2 GO:1904893 negative regulation of receptor signaling pathway via STAT 2/389 34/18722 0.156848851518205 0.567540651210662 PPARG/HGS 2 GO:0007266 Rho protein signal transduction 5/389 137/18722 0.157019061439966 0.567540651210662 MET/CDC42EP4/NRP1/ABL1/ADGRG1 5 GO:0050714 positive regulation of protein secretion 5/389 137/18722 0.157019061439966 0.567540651210662 UNC13B/GJA1/WLS/LRP1/EGFR 5 GO:0090090 negative regulation of canonical Wnt signaling pathway 5/389 137/18722 0.157019061439966 0.567540651210662 GLI3/TPBG/TMEM170B/CTNND1/STK3 5 GO:0030193 regulation of blood coagulation 3/389 66/18722 0.1577468966653 0.568481158239475 PLAU/SERPINE2/ANO6 3 GO:0050918 positive chemotaxis 3/389 66/18722 0.1577468966653 0.568481158239475 MET/LRP1/NRP1 3 GO:0050922 negative regulation of chemotaxis 3/389 66/18722 0.1577468966653 0.568481158239475 SEMA4G/SEMA6A/NRP1 3 GO:0048771 tissue remodeling 6/389 175/18722 0.157962493302307 0.568696162955099 ELF3/LRP5/GJA1/TFRC/MMP14/EGFR 6 GO:0046879 hormone secretion 9/389 295/18722 0.16266159821326 0.580806411820494 LRP5/GJA1/LRP1/KDM5B/RAB11FIP3/HMGCR/SLC16A1/CAMK2G/EGFR 9 GO:0048814 regulation of dendrite morphogenesis 3/389 67/18722 0.162768040169992 0.580806411820494 LZTS1/CDKL3/RAPGEF2 3 GO:0061180 mammary gland epithelium development 3/389 67/18722 0.162768040169992 0.580806411820494 LRP5/KDM5B/FGFR2 3 GO:0070527 platelet aggregation 3/389 67/18722 0.162768040169992 0.580806411820494 SLC7A11/SERPINE2/IL6ST 3 GO:0043547 positive regulation of GTPase activity 8/389 255/18722 0.162858082485451 0.580806411820494 RUNDC1/EPHA1/MYO9A/ITGA6/FERMT2/PLXNB1/RAPGEF2/EZH2 8 GO:0055074 calcium ion homeostasis 13/389 460/18722 0.163634529414561 0.580806411820494 SLC35G1/ATP7B/GJA1/LRP1/C19orf12/TRIM24/ACKR2/ABL1/CLN3/TMTC2/CHERP/DMD/ITGAV 13 GO:0016579 protein deubiquitination 5/389 139/18722 0.16371388430057 0.580806411820494 USP43/USP40/OTUD3/USP5/USP27X 5 GO:0051302 regulation of cell division 6/389 177/18722 0.163841744182841 0.580806411820494 ASPM/MAP10/RACGAP1/FGFR2/RAB11FIP3/BLM 6 GO:0000460 maturation of 5.8S rRNA 2/389 35/18722 0.16419287375567 0.580806411820494 RCL1/RPF1 2 GO:0008608 attachment of spindle microtubules to kinetochore 2/389 35/18722 0.16419287375567 0.580806411820494 CENPE/RACGAP1 2 GO:0010765 positive regulation of sodium ion transport 2/389 35/18722 0.16419287375567 0.580806411820494 PRSS8/DMD 2 GO:0010837 regulation of keratinocyte proliferation 2/389 35/18722 0.16419287375567 0.580806411820494 YAP1/FGFR2 2 GO:0021955 central nervous system neuron axonogenesis 2/389 35/18722 0.16419287375567 0.580806411820494 EPHB3/FBXO45 2 GO:0032232 negative regulation of actin filament bundle assembly 2/389 35/18722 0.16419287375567 0.580806411820494 MET/TJP1 2 GO:0033146 regulation of intracellular estrogen receptor signaling pathway 2/389 35/18722 0.16419287375567 0.580806411820494 YAP1/SKP2 2 GO:0044273 sulfur compound catabolic process 2/389 35/18722 0.16419287375567 0.580806411820494 MPST/BLMH 2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 2/389 35/18722 0.16419287375567 0.580806411820494 NRP1/ABL1 2 GO:0106056 regulation of calcineurin-mediated signaling 2/389 35/18722 0.16419287375567 0.580806411820494 CHERP/FHL2 2 GO:0007265 Ras protein signal transduction 10/389 337/18722 0.165706093242681 0.585591203542691 MET/WASF1/CDC42EP4/HACE1/NRP1/ABL1/CYFIP1/RAPGEF2/ADGRG1/STK19 10 GO:0030004 cellular monovalent inorganic cation homeostasis 4/389 103/18722 0.166779912414856 0.586864850138986 SLC1A3/CLN3/TMEM175/TM9SF4 4 GO:0035265 organ growth 6/389 178/18722 0.166816129025468 0.586864850138986 WWC1/GJA1/YAP1/FGFR2/WWC3/STK3 6 GO:0048015 phosphatidylinositol-mediated signaling 6/389 178/18722 0.166816129025468 0.586864850138986 CA8/PLXNB1/SERPINE2/ERBB3/PTK2/EGFR 6 GO:0007596 blood coagulation 7/389 217/18722 0.166910704773385 0.586864850138986 F5/PLAU/SLC7A11/SERPINE2/GGCX/IL6ST/ANO6 7 GO:0050768 negative regulation of neurogenesis 5/389 140/18722 0.167103661156284 0.586864850138986 SEMA4G/SEMA6A/NRP1/CDKL3/RAPGEF2 5 GO:0010812 negative regulation of cell-substrate adhesion 3/389 68/18722 0.167836588619403 0.586864850138986 LRP1/GCNT2/MMP14 3 GO:0034394 protein localization to cell surface 3/389 68/18722 0.167836588619403 0.586864850138986 LRIG2/JAM3/TM9SF4 3 GO:0042698 ovulation cycle 3/389 68/18722 0.167836588619403 0.586864850138986 ADAMTS1/PCNA/EGFR 3 GO:0046686 response to cadmium ion 3/389 68/18722 0.167836588619403 0.586864850138986 MT1A/PCNA/EGFR 3 GO:0060411 cardiac septum morphogenesis 3/389 68/18722 0.167836588619403 0.586864850138986 LRP2/NRP1/FGFR2 3 GO:1900046 regulation of hemostasis 3/389 68/18722 0.167836588619403 0.586864850138986 PLAU/SERPINE2/ANO6 3 GO:0050803 regulation of synapse structure or activity 7/389 218/18722 0.169606383930542 0.592485136201807 EPHB3/SLC7A11/DAG1/TPBG/ABL1/CLN3/CYFIP1 7 GO:0007416 synapse assembly 6/389 179/18722 0.169813271568058 0.592640192735605 EPHB3/FZD5/CDH1/FBXO45/TPBG/PLXNB1 6 GO:0048284 organelle fusion 5/389 141/18722 0.170521026748396 0.593003622140022 SYT1/RAB7B/TFRC/CLN3/TMEM175 5 GO:0050921 positive regulation of chemotaxis 5/389 141/18722 0.170521026748396 0.593003622140022 MET/NRP1/TPBG/PTK2/ANO6 5 GO:0010762 regulation of fibroblast migration 2/389 36/18722 0.171596331716531 0.593003622140022 CLN3/PTK2 2 GO:0036314 response to sterol 2/389 36/18722 0.171596331716531 0.593003622140022 DAG1/HMGCR 2 GO:0060251 regulation of glial cell proliferation 2/389 36/18722 0.171596331716531 0.593003622140022 PRKCH/EGFR 2 GO:1901990 regulation of mitotic cell cycle phase transition 9/389 299/18722 0.171769622316569 0.593003622140022 CENPE/ADAMTS1/DCUN1D3/FZR1/BLM/ANKRD17/EZH2/EGFR/ECD 9 GO:0009746 response to hexose 7/389 219/18722 0.17232113079189 0.593003622140022 UNC13B/CTSV/LRP5/GJA1/LRP1/HMGCR/XBP1 7 GO:0071897 DNA biosynthetic process 6/389 180/18722 0.172832854951646 0.593003622140022 USP43/GJA1/POLI/WRNIP1/PCNA/SPRTN 6 GO:0015807 L-amino acid transport 3/389 69/18722 0.172950669707723 0.593003622140022 SLC7A11/SLC1A3/SLC38A9 3 GO:0016050 vesicle organization 9/389 300/18722 0.174083130679553 0.593003622140022 UNC13B/SYT1/HGS/RAB7B/SCARB2/CLN3/SEC24C/TMEM175/SERPINE2 9 GO:0044772 mitotic cell cycle phase transition 12/389 424/18722 0.174422977274518 0.593003622140022 CENPE/LZTS1/ADAMTS1/DCUN1D3/FZR1/BLM/ANKRD17/EZH2/CUL2/EGFR/ECD/SKP2 12 GO:0000041 transition metal ion transport 4/389 105/18722 0.174894354625865 0.593003622140022 ATP7B/TFRC/FKBP4/SLC39A1 4 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 4/389 105/18722 0.174894354625865 0.593003622140022 COBL/CDC42EP4/NRP1/CYFIP1 4 GO:0048705 skeletal system morphogenesis 7/389 220/18722 0.175054723848242 0.593003622140022 LRP5/GLI3/FBN2/MMP14/FGFR2/SLC39A1/CHST11 7 GO:0051091 positive regulation of DNA-binding transcription factor activity 8/389 260/18722 0.175211848362975 0.593003622140022 PRKCH/CYTL1/PPARG/LRP5/RAB7B/TFRC/TRIM27/STK3 8 GO:0006479 protein methylation 6/389 181/18722 0.175874558154957 0.593003622140022 METTL21C/ICMT/SUV39H1/EZH2/SETD4/WDR5 6 GO:0008213 protein alkylation 6/389 181/18722 0.175874558154957 0.593003622140022 METTL21C/ICMT/SUV39H1/EZH2/SETD4/WDR5 6 GO:0042886 amide transport 9/389 301/18722 0.176410993465242 0.593003622140022 LRP2/SLC7A11/LRP5/GJA1/LRP1/HMGCR/SLC16A1/CAMK2G/EGFR 9 GO:0045765 regulation of angiogenesis 10/389 342/18722 0.176467713497734 0.593003622140022 EPHA1/ADAMTS1/SEMA6A/PPARG/COL4A2/TJP1/HGS/NRP1/ABL1/XBP1 10 GO:0006865 amino acid transport 5/389 143/18722 0.177436527667662 0.593003622140022 SLC7A11/SLC1A3/GJA1/SLC38A9/CLN3 5 GO:0051056 regulation of small GTPase mediated signal transduction 9/389 302/18722 0.178753083880212 0.593003622140022 MET/SRGAP3/MYO9A/NRP1/ABL1/RACGAP1/ITGAV/ADGRG1/STK19 9 GO:0048017 inositol lipid-mediated signaling 6/389 182/18722 0.178938056147304 0.593003622140022 CA8/PLXNB1/SERPINE2/ERBB3/PTK2/EGFR 6 GO:0002062 chondrocyte differentiation 4/389 106/18722 0.179001661434427 0.593003622140022 CYTL1/GLI3/ZNF219/CHST11 4 GO:0006906 vesicle fusion 4/389 106/18722 0.179001661434427 0.593003622140022 SYT1/RAB7B/CLN3/TMEM175 4 GO:0000154 rRNA modification 2/389 37/18722 0.179053605428139 0.593003622140022 MRM1/NSUN4 2 GO:0006623 protein targeting to vacuole 2/389 37/18722 0.179053605428139 0.593003622140022 HGS/SCARB2 2 GO:0006862 nucleotide transport 2/389 37/18722 0.179053605428139 0.593003622140022 GJA1/SLC25A4 2 GO:0031646 positive regulation of nervous system process 2/389 37/18722 0.179053605428139 0.593003622140022 UNC13B/DAG1 2 GO:0032570 response to progesterone 2/389 37/18722 0.179053605428139 0.593003622140022 CLDN4/YAP1 2 GO:0033260 nuclear DNA replication 2/389 37/18722 0.179053605428139 0.593003622140022 PCNA/BLM 2 GO:0043403 skeletal muscle tissue regeneration 2/389 37/18722 0.179053605428139 0.593003622140022 DAG1/EZH2 2 GO:0043687 post-translational protein modification 2/389 37/18722 0.179053605428139 0.593003622140022 ICMT/P3H1 2 GO:0060428 lung epithelium development 2/389 37/18722 0.179053605428139 0.593003622140022 YAP1/FGFR2 2 GO:1900016 negative regulation of cytokine production involved in inflammatory response 2/389 37/18722 0.179053605428139 0.593003622140022 EZH2/CHID1 2 GO:1905332 positive regulation of morphogenesis of an epithelium 2/389 37/18722 0.179053605428139 0.593003622140022 GJA1/ABL1 2 GO:0031331 positive regulation of cellular catabolic process 12/389 427/18722 0.180291877385306 0.593003622140022 LRP2/LRP1/TMTC3/USP5/MAGEF1/FZR1/TRIB1/TRIM27/CEBPA/SLC25A4/PTK2/RNF19B 12 GO:0032103 positive regulation of response to external stimulus 12/389 427/18722 0.180291877385306 0.593003622140022 MET/LRP1/NRP1/TPBG/POLR3F/ANKRD17/CEBPA/SETD4/PTK2/IL6ST/EGFR/ANO6 12 GO:0007599 hemostasis 7/389 222/18722 0.180577546646346 0.593003622140022 F5/PLAU/SLC7A11/SERPINE2/GGCX/IL6ST/ANO6 7 GO:0050817 coagulation 7/389 222/18722 0.180577546646346 0.593003622140022 F5/PLAU/SLC7A11/SERPINE2/GGCX/IL6ST/ANO6 7 GO:0007612 learning 5/389 144/18722 0.180933652528268 0.593003622140022 SLC7A11/MEIS2/TPBG/CLN3/HMGCR 5 GO:0010821 regulation of mitochondrion organization 5/389 144/18722 0.180933652528268 0.593003622140022 FZD5/PPARG/TFRC/MIEF2/SLC25A4 5 GO:0014065 phosphatidylinositol 3-kinase signaling 5/389 144/18722 0.180933652528268 0.593003622140022 PLXNB1/SERPINE2/ERBB3/PTK2/EGFR 5 GO:0010927 cellular component assembly involved in morphogenesis 4/389 107/18722 0.18314118068358 0.593003622140022 ITGB4/DAG1/EPB41L3/GPC1 4 GO:0021761 limbic system development 4/389 107/18722 0.18314118068358 0.593003622140022 GLI3/NRP1/FGFR2/EZH2 4 GO:0050818 regulation of coagulation 3/389 71/18722 0.183307993640405 0.593003622140022 PLAU/SERPINE2/ANO6 3 GO:0072078 nephron tubule morphogenesis 3/389 71/18722 0.183307993640405 0.593003622140022 GLI3/LAMA5/AHI1 3 GO:0051961 negative regulation of nervous system development 5/389 145/18722 0.184456345774811 0.593003622140022 SEMA4G/SEMA6A/NRP1/CDKL3/RAPGEF2 5 GO:0015833 peptide transport 8/389 264/18722 0.185386919765165 0.593003622140022 SLC7A11/LRP5/GJA1/LRP1/HMGCR/SLC16A1/CAMK2G/EGFR 8 GO:0000578 embryonic axis specification 2/389 38/18722 0.18655928168639 0.593003622140022 FZD5/COBL 2 GO:0032373 positive regulation of sterol transport 2/389 38/18722 0.18655928168639 0.593003622140022 PPARG/LRP1 2 GO:0032376 positive regulation of cholesterol transport 2/389 38/18722 0.18655928168639 0.593003622140022 PPARG/LRP1 2 GO:0009914 hormone transport 9/389 306/18722 0.188261117891066 0.593003622140022 LRP5/GJA1/LRP1/KDM5B/RAB11FIP3/HMGCR/SLC16A1/CAMK2G/EGFR 9 GO:0032729 positive regulation of interferon-gamma production 3/389 72/18722 0.188547548871971 0.593003622140022 FZD5/ABL1/TRIM27 3 GO:0035567 non-canonical Wnt signaling pathway 3/389 72/18722 0.188547548871971 0.593003622140022 FZD5/FZD3/ABL1 3 GO:0042246 tissue regeneration 3/389 72/18722 0.188547548871971 0.593003622140022 DAG1/YAP1/EZH2 3 GO:0050709 negative regulation of protein secretion 3/389 72/18722 0.188547548871971 0.593003622140022 RHBDF1/RAB11FIP3/HMGCR 3 GO:0051057 positive regulation of small GTPase mediated signal transduction 3/389 72/18722 0.188547548871971 0.593003622140022 ITGAV/ADGRG1/STK19 3 GO:0055021 regulation of cardiac muscle tissue growth 3/389 72/18722 0.188547548871971 0.593003622140022 GJA1/YAP1/FGFR2 3 GO:0071479 cellular response to ionizing radiation 3/389 72/18722 0.188547548871971 0.593003622140022 ELK1/YAP1/BLM 3 GO:0016485 protein processing 7/389 225/18722 0.188997410819782 0.593003622140022 PLAU/GAS1/GLI3/MMP14/CLN3/SERPINE2/SPRTN 7 GO:0034284 response to monosaccharide 7/389 225/18722 0.188997410819782 0.593003622140022 UNC13B/CTSV/LRP5/GJA1/LRP1/HMGCR/XBP1 7 GO:0000050 urea cycle 1/389 10/18722 0.189429454289313 0.593003622140022 CEBPA 1 GO:0002084 protein depalmitoylation 1/389 10/18722 0.189429454289313 0.593003622140022 ABHD12 1 GO:0003056 regulation of vascular associated smooth muscle contraction 1/389 10/18722 0.189429454289313 0.593003622140022 DOCK5 1 GO:0006547 histidine metabolic process 1/389 10/18722 0.189429454289313 0.593003622140022 MTHFD2L 1 GO:0007028 cytoplasm organization 1/389 10/18722 0.189429454289313 0.593003622140022 TFCP2L1 1 GO:0009113 purine nucleobase biosynthetic process 1/389 10/18722 0.189429454289313 0.593003622140022 SHMT1 1 GO:0009750 response to fructose 1/389 10/18722 0.189429454289313 0.593003622140022 XBP1 1 GO:0010172 embryonic body morphogenesis 1/389 10/18722 0.189429454289313 0.593003622140022 DAG1 1 GO:0010944 negative regulation of transcription by competitive promoter binding 1/389 10/18722 0.189429454289313 0.593003622140022 BHLHE41 1 GO:0014041 regulation of neuron maturation 1/389 10/18722 0.189429454289313 0.593003622140022 RAC3 1 GO:0015911 long-chain fatty acid import across plasma membrane 1/389 10/18722 0.189429454289313 0.593003622140022 SLC2A1 1 GO:0016081 synaptic vesicle docking 1/389 10/18722 0.189429454289313 0.593003622140022 UNC13B 1 GO:0016559 peroxisome fission 1/389 10/18722 0.189429454289313 0.593003622140022 PEX11A 1 GO:0019532 oxalate transport 1/389 10/18722 0.189429454289313 0.593003622140022 SLC26A2 1 GO:0021562 vestibulocochlear nerve development 1/389 10/18722 0.189429454289313 0.593003622140022 NRP1 1 GO:0021932 hindbrain radial glia guided cell migration 1/389 10/18722 0.189429454289313 0.593003622140022 RBFOX2 1 GO:0031055 chromatin remodeling at centromere 1/389 10/18722 0.189429454289313 0.593003622140022 HELLS 1 GO:0031340 positive regulation of vesicle fusion 1/389 10/18722 0.189429454289313 0.593003622140022 SYT1 1 GO:0032070 regulation of deoxyribonuclease activity 1/389 10/18722 0.189429454289313 0.593003622140022 PCNA 1 GO:0033572 transferrin transport 1/389 10/18722 0.189429454289313 0.593003622140022 TFRC 1 GO:0035376 sterol import 1/389 10/18722 0.189429454289313 0.593003622140022 LRP1 1 GO:0035871 protein K11-linked deubiquitination 1/389 10/18722 0.189429454289313 0.593003622140022 OTUD3 1 GO:0038003 G protein-coupled opioid receptor signaling pathway 1/389 10/18722 0.189429454289313 0.593003622140022 SIGMAR1 1 GO:0038007 netrin-activated signaling pathway 1/389 10/18722 0.189429454289313 0.593003622140022 PTK2 1 GO:0042996 regulation of Golgi to plasma membrane protein transport 1/389 10/18722 0.189429454289313 0.593003622140022 CLN3 1 GO:0043084 penile erection 1/389 10/18722 0.189429454289313 0.593003622140022 ACVR2A 1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence 1/389 10/18722 0.189429454289313 0.593003622140022 EMC1 1 GO:0045348 positive regulation of MHC class II biosynthetic process 1/389 10/18722 0.189429454289313 0.593003622140022 XBP1 1 GO:0048672 positive regulation of collateral sprouting 1/389 10/18722 0.189429454289313 0.593003622140022 LRP1 1 GO:0048703 embryonic viscerocranium morphogenesis 1/389 10/18722 0.189429454289313 0.593003622140022 CHST11 1 GO:0048755 branching morphogenesis of a nerve 1/389 10/18722 0.189429454289313 0.593003622140022 FGFR2 1 GO:0050861 positive regulation of B cell receptor signaling pathway 1/389 10/18722 0.189429454289313 0.593003622140022 PRKCH 1 GO:0060068 vagina development 1/389 10/18722 0.189429454289313 0.593003622140022 LRP2 1 GO:0060525 prostate glandular acinus development 1/389 10/18722 0.189429454289313 0.593003622140022 FGFR2 1 GO:0060736 prostate gland growth 1/389 10/18722 0.189429454289313 0.593003622140022 FGFR2 1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus 1/389 10/18722 0.189429454289313 0.593003622140022 HMGCR 1 GO:0070508 cholesterol import 1/389 10/18722 0.189429454289313 0.593003622140022 LRP1 1 GO:0070561 vitamin D receptor signaling pathway 1/389 10/18722 0.189429454289313 0.593003622140022 TRIM24 1 GO:0071600 otic vesicle morphogenesis 1/389 10/18722 0.189429454289313 0.593003622140022 FGFR2 1 GO:0072178 nephric duct morphogenesis 1/389 10/18722 0.189429454289313 0.593003622140022 AHI1 1 GO:0097084 vascular associated smooth muscle cell development 1/389 10/18722 0.189429454289313 0.593003622140022 SGCB 1 GO:0098917 retrograde trans-synaptic signaling 1/389 10/18722 0.189429454289313 0.593003622140022 DAG1 1 GO:1900246 positive regulation of RIG-I signaling pathway 1/389 10/18722 0.189429454289313 0.593003622140022 ANKRD17 1 GO:1901203 positive regulation of extracellular matrix assembly 1/389 10/18722 0.189429454289313 0.593003622140022 DAG1 1 GO:1901524 regulation of mitophagy 1/389 10/18722 0.189429454289313 0.593003622140022 SLC25A4 1 GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 1/389 10/18722 0.189429454289313 0.593003622140022 IPPK 1 GO:1902023 L-arginine transport 1/389 10/18722 0.189429454289313 0.593003622140022 SLC38A9 1 GO:1902946 protein localization to early endosome 1/389 10/18722 0.189429454289313 0.593003622140022 NRP1 1 GO:1903826 arginine transmembrane transport 1/389 10/18722 0.189429454289313 0.593003622140022 SLC38A9 1 GO:1903867 extraembryonic membrane development 1/389 10/18722 0.189429454289313 0.593003622140022 FZD5 1 GO:1904526 regulation of microtubule binding 1/389 10/18722 0.189429454289313 0.593003622140022 ABL1 1 GO:1904668 positive regulation of ubiquitin protein ligase activity 1/389 10/18722 0.189429454289313 0.593003622140022 FZR1 1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus 1/389 10/18722 0.189429454289313 0.593003622140022 WASF1 1 GO:1990700 nucleolar chromatin organization 1/389 10/18722 0.189429454289313 0.593003622140022 SUV39H1 1 GO:2000169 regulation of peptidyl-cysteine S-nitrosylation 1/389 10/18722 0.189429454289313 0.593003622140022 DMD 1 GO:2000288 positive regulation of myoblast proliferation 1/389 10/18722 0.189429454289313 0.593003622140022 MEIS2 1 GO:2000434 regulation of protein neddylation 1/389 10/18722 0.189429454289313 0.593003622140022 DCUN1D3 1 GO:2001223 negative regulation of neuron migration 1/389 10/18722 0.189429454289313 0.593003622140022 ADGRG1 1 GO:2001225 regulation of chloride transport 1/389 10/18722 0.189429454289313 0.593003622140022 GABRE 1 GO:1901342 regulation of vasculature development 10/389 348/18722 0.189800881606093 0.593656788351133 EPHA1/ADAMTS1/SEMA6A/PPARG/COL4A2/TJP1/HGS/NRP1/ABL1/XBP1 10 GO:0072009 nephron epithelium development 4/389 109/18722 0.191513304338705 0.597496952254571 GLI3/YAP1/LAMA5/AHI1 4 GO:0006486 protein glycosylation 7/389 226/18722 0.191839256824721 0.597496952254571 UGGT2/PMM1/GCNT2/TMTC2/TMTC3/GALNT11/EXTL2 7 GO:0043413 macromolecule glycosylation 7/389 226/18722 0.191839256824721 0.597496952254571 UGGT2/PMM1/GCNT2/TMTC2/TMTC3/GALNT11/EXTL2 7 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 3/389 73/18722 0.193825263958873 0.597496952254571 LRP5/LRP1/HMGCR 3 GO:0050848 regulation of calcium-mediated signaling 3/389 73/18722 0.193825263958873 0.597496952254571 PDK2/CHERP/FHL2 3 GO:0051145 smooth muscle cell differentiation 3/389 73/18722 0.193825263958873 0.597496952254571 FGFR2/ANKRD17/SGCB 3 GO:0072088 nephron epithelium morphogenesis 3/389 73/18722 0.193825263958873 0.597496952254571 GLI3/LAMA5/AHI1 3 GO:0099518 vesicle cytoskeletal trafficking 3/389 73/18722 0.193825263958873 0.597496952254571 CLN3/DYNC1H1/MYO1C 3 GO:0007618 mating 2/389 39/18722 0.194108147926755 0.597496952254571 ACVR2A/SERPINE2 2 GO:0010463 mesenchymal cell proliferation 2/389 39/18722 0.194108147926755 0.597496952254571 LRP5/FGFR2 2 GO:0021587 cerebellum morphogenesis 2/389 39/18722 0.194108147926755 0.597496952254571 ABL1/SERPINE2 2 GO:0071548 response to dexamethasone 2/389 39/18722 0.194108147926755 0.597496952254571 PCNA/EGFR 2 GO:0090174 organelle membrane fusion 4/389 110/18722 0.195744127176086 0.597496952254571 SYT1/RAB7B/CLN3/TMEM175 4 GO:0009411 response to UV 5/389 149/18722 0.198792423287404 0.597496952254571 DCUN1D3/SCARA3/PCNA/EGFR/SPRTN 5 GO:0016525 negative regulation of angiogenesis 5/389 149/18722 0.198792423287404 0.597496952254571 ADAMTS1/SEMA6A/PPARG/COL4A2/HGS 5 GO:0003151 outflow tract morphogenesis 3/389 74/18722 0.199139330926284 0.597496952254571 LRP2/NRP1/FGFR2 3 GO:0048844 artery morphogenesis 3/389 74/18722 0.199139330926284 0.597496952254571 LRP2/LRP1/NRP1 3 GO:0010543 regulation of platelet activation 2/389 40/18722 0.201695186259682 0.597496952254571 SERPINE2/IL6ST 2 GO:0030866 cortical actin cytoskeleton organization 2/389 40/18722 0.201695186259682 0.597496952254571 RACGAP1/EPB41L3 2 GO:0031297 replication fork processing 2/389 40/18722 0.201695186259682 0.597496952254571 PCNA/BLM 2 GO:0044275 cellular carbohydrate catabolic process 2/389 40/18722 0.201695186259682 0.597496952254571 SCARB2/ENOSF1 2 GO:0045740 positive regulation of DNA replication 2/389 40/18722 0.201695186259682 0.597496952254571 PCNA/EGFR 2 GO:0071276 cellular response to cadmium ion 2/389 40/18722 0.201695186259682 0.597496952254571 MT1A/EGFR 2 GO:0009755 hormone-mediated signaling pathway 6/389 190/18722 0.204190445979224 0.597496952254571 LGR5/PPARG/YAP1/RBFOX2/PRLR/SKP2 6 GO:0099111 microtubule-based transport 6/389 190/18722 0.204190445979224 0.597496952254571 DST/WASF1/CLN3/ARL3/SPAG16/DYNC1H1 6 GO:0001676 long-chain fatty acid metabolic process 4/389 112/18722 0.204290830388323 0.597496952254571 SLC27A2/SLC27A6/ABHD12/ACSF2 4 GO:0008088 axo-dendritic transport 3/389 75/18722 0.204487958073488 0.597496952254571 DST/WASF1/DYNC1H1 3 GO:0036465 synaptic vesicle recycling 3/389 75/18722 0.204487958073488 0.597496952254571 SYNJ2/SYT1/CYFIP1 3 GO:0043627 response to estrogen 3/389 75/18722 0.204487958073488 0.597496952254571 GLI3/TRIM24/MMP14 3 GO:0048662 negative regulation of smooth muscle cell proliferation 3/389 75/18722 0.204487958073488 0.597496952254571 NDRG2/PPARG/TRIB1 3 GO:0051453 regulation of intracellular pH 3/389 75/18722 0.204487958073488 0.597496952254571 CLN3/TMEM175/TM9SF4 3 GO:0055067 monovalent inorganic cation homeostasis 5/389 151/18722 0.206100282090483 0.597496952254571 SLC1A3/PDK2/CLN3/TMEM175/TM9SF4 5 GO:0071333 cellular response to glucose stimulus 5/389 151/18722 0.206100282090483 0.597496952254571 UNC13B/LRP5/LRP1/HMGCR/XBP1 5 GO:2000181 negative regulation of blood vessel morphogenesis 5/389 151/18722 0.206100282090483 0.597496952254571 ADAMTS1/SEMA6A/PPARG/COL4A2/HGS 5 GO:2001236 regulation of extrinsic apoptotic signaling pathway 5/389 151/18722 0.206100282090483 0.597496952254571 ITGA6/YAP1/NRP1/STK3/ITGAV 5 GO:0002327 immature B cell differentiation 1/389 11/18722 0.206280242141037 0.597496952254571 ABL1 1 GO:0003093 regulation of glomerular filtration 1/389 11/18722 0.206280242141037 0.597496952254571 GJA1 1 GO:0003139 secondary heart field specification 1/389 11/18722 0.206280242141037 0.597496952254571 LRP2 1 GO:0003157 endocardium development 1/389 11/18722 0.206280242141037 0.597496952254571 STK3 1 GO:0006020 inositol metabolic process 1/389 11/18722 0.206280242141037 0.597496952254571 IPPK 1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate 1/389 11/18722 0.206280242141037 0.597496952254571 PDK2 1 GO:0007042 lysosomal lumen acidification 1/389 11/18722 0.206280242141037 0.597496952254571 CLN3 1 GO:0009235 cobalamin metabolic process 1/389 11/18722 0.206280242141037 0.597496952254571 MMAB 1 GO:0010887 negative regulation of cholesterol storage 1/389 11/18722 0.206280242141037 0.597496952254571 PPARG 1 GO:0014854 response to inactivity 1/389 11/18722 0.206280242141037 0.597496952254571 DAG1 1 GO:0015937 coenzyme A biosynthetic process 1/389 11/18722 0.206280242141037 0.597496952254571 COASY 1 GO:0018026 peptidyl-lysine monomethylation 1/389 11/18722 0.206280242141037 0.597496952254571 SETD4 1 GO:0021561 facial nerve development 1/389 11/18722 0.206280242141037 0.597496952254571 NRP1 1 GO:0021604 cranial nerve structural organization 1/389 11/18722 0.206280242141037 0.597496952254571 NRP1 1 GO:0021610 facial nerve morphogenesis 1/389 11/18722 0.206280242141037 0.597496952254571 NRP1 1 GO:0021860 pyramidal neuron development 1/389 11/18722 0.206280242141037 0.597496952254571 FGFR2 1 GO:0021892 cerebral cortex GABAergic interneuron differentiation 1/389 11/18722 0.206280242141037 0.597496952254571 RAC3 1 GO:0030210 heparin biosynthetic process 1/389 11/18722 0.206280242141037 0.597496952254571 GLCE 1 GO:0032276 regulation of gonadotropin secretion 1/389 11/18722 0.206280242141037 0.597496952254571 GJA1 1 GO:0033625 positive regulation of integrin activation 1/389 11/18722 0.206280242141037 0.597496952254571 FERMT2 1 GO:0034163 regulation of toll-like receptor 9 signaling pathway 1/389 11/18722 0.206280242141037 0.597496952254571 RAB7B 1 GO:0034350 regulation of glial cell apoptotic process 1/389 11/18722 0.206280242141037 0.597496952254571 PRKCH 1 GO:0034770 histone H4-K20 methylation 1/389 11/18722 0.206280242141037 0.597496952254571 SETD4 1 GO:0034975 protein folding in endoplasmic reticulum 1/389 11/18722 0.206280242141037 0.597496952254571 ERO1B 1 GO:0039530 MDA-5 signaling pathway 1/389 11/18722 0.206280242141037 0.597496952254571 ANKRD17 1 GO:0044068 modulation by symbiont of host cellular process 1/389 11/18722 0.206280242141037 0.597496952254571 ANO6 1 GO:0045060 negative thymic T cell selection 1/389 11/18722 0.206280242141037 0.597496952254571 GLI3 1 GO:0045654 positive regulation of megakaryocyte differentiation 1/389 11/18722 0.206280242141037 0.597496952254571 RAB7B 1 GO:0045945 positive regulation of transcription by RNA polymerase III 1/389 11/18722 0.206280242141037 0.597496952254571 CEBPA 1 GO:0046710 GDP metabolic process 1/389 11/18722 0.206280242141037 0.597496952254571 TJP2 1 GO:0048102 autophagic cell death 1/389 11/18722 0.206280242141037 0.597496952254571 CTSV 1 GO:0048680 positive regulation of axon regeneration 1/389 11/18722 0.206280242141037 0.597496952254571 LRP1 1 GO:0051657 maintenance of organelle location 1/389 11/18722 0.206280242141037 0.597496952254571 ASPM 1 GO:0055015 ventricular cardiac muscle cell development 1/389 11/18722 0.206280242141037 0.597496952254571 FHL2 1 GO:0060579 ventral spinal cord interneuron fate commitment 1/389 11/18722 0.206280242141037 0.597496952254571 GLI3 1 GO:0060581 cell fate commitment involved in pattern specification 1/389 11/18722 0.206280242141037 0.597496952254571 GLI3 1 GO:0060742 epithelial cell differentiation involved in prostate gland development 1/389 11/18722 0.206280242141037 0.597496952254571 FGFR2 1 GO:0060746 parental behavior 1/389 11/18722 0.206280242141037 0.597496952254571 ZFX 1 GO:0060837 blood vessel endothelial cell differentiation 1/389 11/18722 0.206280242141037 0.597496952254571 NRP1 1 GO:0061314 Notch signaling involved in heart development 1/389 11/18722 0.206280242141037 0.597496952254571 GALNT11 1 GO:0070314 G1 to G0 transition 1/389 11/18722 0.206280242141037 0.597496952254571 EZH2 1 GO:0070778 L-aspartate transmembrane transport 1/389 11/18722 0.206280242141037 0.597496952254571 SLC1A3 1 GO:0090160 Golgi to lysosome transport 1/389 11/18722 0.206280242141037 0.597496952254571 CLN3 1 GO:0090657 telomeric loop disassembly 1/389 11/18722 0.206280242141037 0.597496952254571 BLM 1 GO:0090660 cerebrospinal fluid circulation 1/389 11/18722 0.206280242141037 0.597496952254571 SPAG16 1 GO:0097048 dendritic cell apoptotic process 1/389 11/18722 0.206280242141037 0.597496952254571 RAPGEF2 1 GO:0098935 dendritic transport 1/389 11/18722 0.206280242141037 0.597496952254571 WASF1 1 GO:0106049 regulation of cellular response to osmotic stress 1/389 11/18722 0.206280242141037 0.597496952254571 CLN3 1 GO:0140042 lipid droplet formation 1/389 11/18722 0.206280242141037 0.597496952254571 CDS1 1 GO:1900222 negative regulation of amyloid-beta clearance 1/389 11/18722 0.206280242141037 0.597496952254571 HMGCR 1 GO:1902065 response to L-glutamate 1/389 11/18722 0.206280242141037 0.597496952254571 PCNA 1 GO:1902667 regulation of axon guidance 1/389 11/18722 0.206280242141037 0.597496952254571 NRP1 1 GO:1903961 positive regulation of anion transmembrane transport 1/389 11/18722 0.206280242141037 0.597496952254571 TCAF1 1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin 1/389 11/18722 0.206280242141037 0.597496952254571 TJP1 1 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 1/389 11/18722 0.206280242141037 0.597496952254571 LRP1 1 GO:2000668 regulation of dendritic cell apoptotic process 1/389 11/18722 0.206280242141037 0.597496952254571 RAPGEF2 1 GO:0051090 regulation of DNA-binding transcription factor activity 12/389 440/18722 0.20678061126825 0.597496952254571 PRKCH/C3orf33/CYTL1/PPARG/LRP5/RAB7B/TFRC/TRIB1/TRIM27/EZH2/STK3/NLRP2 12 GO:0050821 protein stabilization 6/389 191/18722 0.207434884176611 0.597496952254571 AAK1/OTUD3/CTNND1/P3H1/STK3/USP27X 6 GO:0006605 protein targeting 9/389 314/18722 0.207919194100686 0.597496952254571 FZD5/ARL6/HGS/SCARB2/MICALL1/ICMT/MIEF2/TCAF1/MYO1C 9 GO:0045936 negative regulation of phosphate metabolic process 12/389 441/18722 0.208886333556014 0.597496952254571 EPHA1/SPRED2/PPARG/LRP5/NR2F2/LRP1/ABL1/HMGCR/TRIB1/TRIM27/CEBPA/DMD 12 GO:0001953 negative regulation of cell-matrix adhesion 2/389 41/18722 0.209315567666213 0.597496952254571 LRP1/MMP14 2 GO:0006418 tRNA aminoacylation for protein translation 2/389 41/18722 0.209315567666213 0.597496952254571 TARS2/HARS2 2 GO:0007099 centriole replication 2/389 41/18722 0.209315567666213 0.597496952254571 CEP76/CEP44 2 GO:0042307 positive regulation of protein import into nucleus 2/389 41/18722 0.209315567666213 0.597496952254571 CDH1/GLI3 2 GO:0044786 cell cycle DNA replication 2/389 41/18722 0.209315567666213 0.597496952254571 PCNA/BLM 2 GO:0048286 lung alveolus development 2/389 41/18722 0.209315567666213 0.597496952254571 SLC7A11/FGFR2 2 GO:0050892 intestinal absorption 2/389 41/18722 0.209315567666213 0.597496952254571 TJP2/LIMA1 2 GO:0055023 positive regulation of cardiac muscle tissue growth 2/389 41/18722 0.209315567666213 0.597496952254571 YAP1/FGFR2 2 GO:0060612 adipose tissue development 2/389 41/18722 0.209315567666213 0.597496952254571 LRP5/XBP1 2 GO:0071470 cellular response to osmotic stress 2/389 41/18722 0.209315567666213 0.597496952254571 CLN3/SLC2A1 2 GO:0071634 regulation of transforming growth factor beta production 2/389 41/18722 0.209315567666213 0.597496952254571 LTBP1/ITGAV 2 GO:1905521 regulation of macrophage migration 2/389 41/18722 0.209315567666213 0.597496952254571 MMP14/PTK2 2 GO:2000008 regulation of protein localization to cell surface 2/389 41/18722 0.209315567666213 0.597496952254571 LRIG2/TM9SF4 2 GO:0030509 BMP signaling pathway 5/389 152/18722 0.209787304986691 0.597496952254571 LRP2/BAMBI/PPARG/ACVR2A/ABL1 5 GO:1901343 negative regulation of vasculature development 5/389 152/18722 0.209787304986691 0.597496952254571 ADAMTS1/SEMA6A/PPARG/COL4A2/HGS 5 GO:0001937 negative regulation of endothelial cell proliferation 3/389 76/18722 0.209869370945464 0.597496952254571 PPARG/NR2F2/GJA1 3 GO:0006305 DNA alkylation 3/389 76/18722 0.209869370945464 0.597496952254571 DNMT3A/EZH2/HELLS 3 GO:0006306 DNA methylation 3/389 76/18722 0.209869370945464 0.597496952254571 DNMT3A/EZH2/HELLS 3 GO:0014855 striated muscle cell proliferation 3/389 76/18722 0.209869370945464 0.597496952254571 GJA1/YAP1/FGFR2 3 GO:0072028 nephron morphogenesis 3/389 76/18722 0.209869370945464 0.597496952254571 GLI3/LAMA5/AHI1 3 GO:0010563 negative regulation of phosphorus metabolic process 12/389 442/18722 0.21100138701239 0.599177367684467 EPHA1/SPRED2/PPARG/LRP5/NR2F2/LRP1/ABL1/HMGCR/TRIB1/TRIM27/CEBPA/DMD 12 GO:0002244 hematopoietic progenitor cell differentiation 4/389 114/18722 0.212944984632216 0.599177367684467 PYGO1/JAM3/ABL1/RBM47 4 GO:0071331 cellular response to hexose stimulus 5/389 153/18722 0.21349567439803 0.599177367684467 UNC13B/LRP5/LRP1/HMGCR/XBP1 5 GO:0001935 endothelial cell proliferation 6/389 193/18722 0.213978473013014 0.599177367684467 EGFL7/PPARG/NR2F2/GJA1/NRP1/MMP14 6 GO:0031016 pancreas development 3/389 77/18722 0.215281813239595 0.599177367684467 MET/WLS/MEIS2 3 GO:0140056 organelle localization by membrane tethering 3/389 77/18722 0.215281813239595 0.599177367684467 UNC13B/SYT1/CLN3 3 GO:0000413 protein peptidyl-prolyl isomerization 2/389 42/18722 0.216964646349761 0.599177367684467 PPIL1/FKBP4 2 GO:0014912 negative regulation of smooth muscle cell migration 2/389 42/18722 0.216964646349761 0.599177367684467 LRP1/TRIB1 2 GO:0021575 hindbrain morphogenesis 2/389 42/18722 0.216964646349761 0.599177367684467 ABL1/SERPINE2 2 GO:0032467 positive regulation of cytokinesis 2/389 42/18722 0.216964646349761 0.599177367684467 MAP10/RACGAP1 2 GO:0035019 somatic stem cell population maintenance 2/389 42/18722 0.216964646349761 0.599177367684467 LRP5/YAP1 2 GO:0046688 response to copper ion 2/389 42/18722 0.216964646349761 0.599177367684467 ATP7B/MT1A 2 GO:0051602 response to electrical stimulus 2/389 42/18722 0.216964646349761 0.599177367684467 FZD3/CYFIP1 2 GO:0055090 acylglycerol homeostasis 2/389 42/18722 0.216964646349761 0.599177367684467 HMGCR/XBP1 2 GO:0070328 triglyceride homeostasis 2/389 42/18722 0.216964646349761 0.599177367684467 HMGCR/XBP1 2 GO:0071312 cellular response to alkaloid 2/389 42/18722 0.216964646349761 0.599177367684467 SLC1A3/BLM 2 GO:1900274 regulation of phospholipase C activity 2/389 42/18722 0.216964646349761 0.599177367684467 ABL1/EGFR 2 GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II 2/389 42/18722 0.216964646349761 0.599177367684467 PPARG/TEAD1 2 GO:0071326 cellular response to monosaccharide stimulus 5/389 154/18722 0.217224850923029 0.599177367684467 UNC13B/LRP5/LRP1/HMGCR/XBP1 5 GO:0034968 histone lysine methylation 4/389 115/18722 0.217310122303108 0.599177367684467 SUV39H1/EZH2/SETD4/WDR5 4 GO:1901989 positive regulation of cell cycle phase transition 4/389 115/18722 0.217310122303108 0.599177367684467 ADAMTS1/ANKRD17/EZH2/EGFR 4 GO:0030073 insulin secretion 6/389 195/18722 0.220592606035963 0.599177367684467 LRP5/GJA1/LRP1/HMGCR/SLC16A1/CAMK2G 6 GO:0030705 cytoskeleton-dependent intracellular transport 6/389 195/18722 0.220592606035963 0.599177367684467 DST/WASF1/CLN3/ARL3/DYNC1H1/MYO1C 6 GO:0030500 regulation of bone mineralization 3/389 78/18722 0.220723547650135 0.599177367684467 ACVR2A/FBN2/ANO6 3 GO:0010970 transport along microtubule 5/389 155/18722 0.220974293431039 0.599177367684467 DST/WASF1/CLN3/ARL3/DYNC1H1 5 GO:0000209 protein polyubiquitination 7/389 236/18722 0.221163196224605 0.599177367684467 HACE1/BLMH/FZR1/TRIM27/KLHL42/SKP2/RNF19B 7 GO:0030072 peptide hormone secretion 7/389 236/18722 0.221163196224605 0.599177367684467 LRP5/GJA1/LRP1/HMGCR/SLC16A1/CAMK2G/EGFR 7 GO:0046395 carboxylic acid catabolic process 7/389 236/18722 0.221163196224605 0.599177367684467 CPT1C/SLC27A2/BCKDHB/BLMH/ENOSF1/GLDC/SHMT1 7 GO:0006720 isoprenoid metabolic process 4/389 116/18722 0.221699444362914 0.599177367684467 LRP2/LRP1/HMGCR/EGFR 4 GO:0021782 glial cell development 4/389 116/18722 0.221699444362914 0.599177367684467 ITGB4/DAG1/LRP1/EGFR 4 GO:0030326 embryonic limb morphogenesis 4/389 116/18722 0.221699444362914 0.599177367684467 LRP5/GLI3/FBN2/CHST11 4 GO:0035113 embryonic appendage morphogenesis 4/389 116/18722 0.221699444362914 0.599177367684467 LRP5/GLI3/FBN2/CHST11 4 GO:0000727 double-strand break repair via break-induced replication 1/389 12/18722 0.222781604217203 0.599177367684467 MCM5 1 GO:0006285 base-excision repair, AP site formation 1/389 12/18722 0.222781604217203 0.599177367684467 TDG 1 GO:0006563 L-serine metabolic process 1/389 12/18722 0.222781604217203 0.599177367684467 SHMT1 1 GO:0009086 methionine biosynthetic process 1/389 12/18722 0.222781604217203 0.599177367684467 MTHFD2L 1 GO:0016188 synaptic vesicle maturation 1/389 12/18722 0.222781604217203 0.599177367684467 UNC13B 1 GO:0016554 cytidine to uridine editing 1/389 12/18722 0.222781604217203 0.599177367684467 RBM47 1 GO:0019627 urea metabolic process 1/389 12/18722 0.222781604217203 0.599177367684467 CEBPA 1 GO:0021559 trigeminal nerve development 1/389 12/18722 0.222781604217203 0.599177367684467 NRP1 1 GO:0021978 telencephalon regionalization 1/389 12/18722 0.222781604217203 0.599177367684467 ADGRG1 1 GO:0030202 heparin metabolic process 1/389 12/18722 0.222781604217203 0.599177367684467 GLCE 1 GO:0031223 auditory behavior 1/389 12/18722 0.222781604217203 0.599177367684467 SLC1A3 1 GO:0033629 negative regulation of cell adhesion mediated by integrin 1/389 12/18722 0.222781604217203 0.599177367684467 JAM3 1 GO:0034333 adherens junction assembly 1/389 12/18722 0.222781604217203 0.599177367684467 JAM3 1 GO:0038180 nerve growth factor signaling pathway 1/389 12/18722 0.222781604217203 0.599177367684467 RAPGEF2 1 GO:0043248 proteasome assembly 1/389 12/18722 0.222781604217203 0.599177367684467 PSMG1 1 GO:0043383 negative T cell selection 1/389 12/18722 0.222781604217203 0.599177367684467 GLI3 1 GO:0043471 regulation of cellular carbohydrate catabolic process 1/389 12/18722 0.222781604217203 0.599177367684467 SCARB2 1 GO:0045117 azole transmembrane transport 1/389 12/18722 0.222781604217203 0.599177367684467 SLC19A3 1 GO:0045605 negative regulation of epidermal cell differentiation 1/389 12/18722 0.222781604217203 0.599177367684467 EZH2 1 GO:0045683 negative regulation of epidermis development 1/389 12/18722 0.222781604217203 0.599177367684467 EZH2 1 GO:0051639 actin filament network formation 1/389 12/18722 0.222781604217203 0.599177367684467 COBL 1 GO:0060019 radial glial cell differentiation 1/389 12/18722 0.222781604217203 0.599177367684467 GLI3 1 GO:0060442 branching involved in prostate gland morphogenesis 1/389 12/18722 0.222781604217203 0.599177367684467 FGFR2 1 GO:0060601 lateral sprouting from an epithelium 1/389 12/18722 0.222781604217203 0.599177367684467 FGFR2 1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1/389 12/18722 0.222781604217203 0.599177367684467 GLI3 1 GO:0061517 macrophage proliferation 1/389 12/18722 0.222781604217203 0.599177367684467 PTK2 1 GO:0070493 thrombin-activated receptor signaling pathway 1/389 12/18722 0.222781604217203 0.599177367684467 MET 1 GO:0070572 positive regulation of neuron projection regeneration 1/389 12/18722 0.222781604217203 0.599177367684467 LRP1 1 GO:0071107 response to parathyroid hormone 1/389 12/18722 0.222781604217203 0.599177367684467 GJA1 1 GO:0071712 ER-associated misfolded protein catabolic process 1/389 12/18722 0.222781604217203 0.599177367684467 UGGT2 1 GO:0071941 nitrogen cycle metabolic process 1/389 12/18722 0.222781604217203 0.599177367684467 CEBPA 1 GO:0072182 regulation of nephron tubule epithelial cell differentiation 1/389 12/18722 0.222781604217203 0.599177367684467 YAP1 1 GO:0072520 seminiferous tubule development 1/389 12/18722 0.222781604217203 0.599177367684467 ADGRG1 1 GO:0072711 cellular response to hydroxyurea 1/389 12/18722 0.222781604217203 0.599177367684467 BLM 1 GO:0090331 negative regulation of platelet aggregation 1/389 12/18722 0.222781604217203 0.599177367684467 SERPINE2 1 GO:0090646 mitochondrial tRNA processing 1/389 12/18722 0.222781604217203 0.599177367684467 ELAC2 1 GO:1901298 regulation of hydrogen peroxide-mediated programmed cell death 1/389 12/18722 0.222781604217203 0.599177367684467 MET 1 GO:1903441 protein localization to ciliary membrane 1/389 12/18722 0.222781604217203 0.599177367684467 ARL3 1 GO:1903599 positive regulation of autophagy of mitochondrion 1/389 12/18722 0.222781604217203 0.599177367684467 SLC25A4 1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA 1/389 12/18722 0.222781604217203 0.599177367684467 EGFR 1 GO:1903909 regulation of receptor clustering 1/389 12/18722 0.222781604217203 0.599177367684467 SLC7A11 1 GO:1990034 calcium ion export across plasma membrane 1/389 12/18722 0.222781604217203 0.599177367684467 SLC35G1 1 GO:2001214 positive regulation of vasculogenesis 1/389 12/18722 0.222781604217203 0.599177367684467 RAPGEF2 1 GO:0022407 regulation of cell-cell adhesion 12/389 448/18722 0.223882893810905 0.599747158941139 EPHB3/TJP1/CDH1/GLI3/TFRC/GCNT2/ABL1/SERPINE2/TENM3/PTK2/IL6ST/XBP1 12 GO:0043393 regulation of protein binding 6/389 196/18722 0.223925216646824 0.599747158941139 BAMBI/LRP1/NRP1/ABL1/RAPGEF2/STK3 6 GO:0090276 regulation of peptide hormone secretion 6/389 196/18722 0.223925216646824 0.599747158941139 LRP5/GJA1/LRP1/HMGCR/SLC16A1/EGFR 6 GO:0006284 base-excision repair 2/389 43/18722 0.224637954240087 0.599747158941139 PCNA/TDG 2 GO:0006509 membrane protein ectodomain proteolysis 2/389 43/18722 0.224637954240087 0.599747158941139 DAG1/LRIG2 2 GO:0010171 body morphogenesis 2/389 43/18722 0.224637954240087 0.599747158941139 DAG1/CRISPLD1 2 GO:0014002 astrocyte development 2/389 43/18722 0.224637954240087 0.599747158941139 LRP1/EGFR 2 GO:0033173 calcineurin-NFAT signaling cascade 2/389 43/18722 0.224637954240087 0.599747158941139 CHERP/FHL2 2 GO:0071604 transforming growth factor beta production 2/389 43/18722 0.224637954240087 0.599747158941139 LTBP1/ITGAV 2 GO:1904591 positive regulation of protein import 2/389 43/18722 0.224637954240087 0.599747158941139 CDH1/GLI3 2 GO:0014902 myotube differentiation 4/389 117/18722 0.226112060866488 0.602135290666632 MMP14/MYOF/BHLHE41/XBP1 4 GO:0030301 cholesterol transport 4/389 117/18722 0.226112060866488 0.602135290666632 PPARG/LRP1/SERAC1/LIMA1 4 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 3/389 79/18722 0.226192856652944 0.602135290666632 PLXNB1/ERBB3/PTK2 3 GO:0060420 regulation of heart growth 3/389 79/18722 0.226192856652944 0.602135290666632 GJA1/YAP1/FGFR2 3 GO:0002262 myeloid cell homeostasis 5/389 157/18722 0.228531804709976 0.605412699002467 SLC7A11/ACVR2A/JAM3/RBFOX2/XKR8 5 GO:0007034 vacuolar transport 5/389 157/18722 0.228531804709976 0.605412699002467 LRP1/HGS/RAB7B/SCARB2/CLN3 5 GO:0070646 protein modification by small protein removal 5/389 157/18722 0.228531804709976 0.605412699002467 USP43/USP40/OTUD3/USP5/USP27X 5 GO:0051403 stress-activated MAPK cascade 7/389 239/18722 0.230258130151835 0.605412699002467 MARVELD3/STK25/HMGCR/TRIB1/IRAK4/STK3/EGFR 7 GO:0071346 cellular response to interferon-gamma 4/389 118/18722 0.23054708404236 0.605412699002467 PPARG/CDC42EP4/RAB7B/MYO1C 4 GO:1901264 carbohydrate derivative transport 3/389 80/18722 0.231688043232969 0.605412699002467 GJA1/CLN3/SLC25A4 3 GO:0002066 columnar/cuboidal epithelial cell development 2/389 44/18722 0.232331195645615 0.605412699002467 YAP1/IL6ST 2 GO:0007528 neuromuscular junction development 2/389 44/18722 0.232331195645615 0.605412699002467 UNC13B/COL4A1 2 GO:0043039 tRNA aminoacylation 2/389 44/18722 0.232331195645615 0.605412699002467 TARS2/HARS2 2 GO:0045124 regulation of bone resorption 2/389 44/18722 0.232331195645615 0.605412699002467 TFRC/EGFR 2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 2/389 44/18722 0.232331195645615 0.605412699002467 MYO9A/FAT1 2 GO:0050999 regulation of nitric-oxide synthase activity 2/389 44/18722 0.232331195645615 0.605412699002467 ACVR2A/EGFR 2 GO:0051150 regulation of smooth muscle cell differentiation 2/389 44/18722 0.232331195645615 0.605412699002467 FGFR2/ANKRD17 2 GO:0089718 amino acid import across plasma membrane 2/389 44/18722 0.232331195645615 0.605412699002467 SLC7A11/SLC1A3 2 GO:0097178 ruffle assembly 2/389 44/18722 0.232331195645615 0.605412699002467 COBL/CYFIP1 2 GO:0030282 bone mineralization 4/389 119/18722 0.235003628728619 0.605412699002467 ACVR2A/FBN2/FGFR2/ANO6 4 GO:0031398 positive regulation of protein ubiquitination 4/389 119/18722 0.235003628728619 0.605412699002467 DCUN1D3/FZR1/SPRTN/SKP2 4 GO:0044262 cellular carbohydrate metabolic process 8/389 283/18722 0.23690050218693 0.605412699002467 SYNJ2/IPPK/PDK2/SCARB2/ENOSF1/GYG1/IL6ST/WDR5 8 GO:0000422 autophagy of mitochondrion 3/389 81/18722 0.237207431556821 0.605412699002467 SPATA18/FZD5/SLC25A4 3 GO:0030641 regulation of cellular pH 3/389 81/18722 0.237207431556821 0.605412699002467 CLN3/TMEM175/TM9SF4 3 GO:0061726 mitochondrion disassembly 3/389 81/18722 0.237207431556821 0.605412699002467 SPATA18/FZD5/SLC25A4 3 GO:0002791 regulation of peptide secretion 6/389 200/18722 0.237417365246819 0.605412699002467 LRP5/GJA1/LRP1/HMGCR/SLC16A1/EGFR 6 GO:0071902 positive regulation of protein serine/threonine kinase activity 6/389 200/18722 0.237417365246819 0.605412699002467 FZD5/FERMT2/RAPGEF2/EZH2/STK3/EGFR 6 GO:0001778 plasma membrane repair 1/389 13/18722 0.238940768084627 0.605412699002467 MYOF 1 GO:0001886 endothelial cell morphogenesis 1/389 13/18722 0.238940768084627 0.605412699002467 MET 1 GO:0005513 detection of calcium ion 1/389 13/18722 0.238940768084627 0.605412699002467 SYT1 1 GO:0007494 midgut development 1/389 13/18722 0.238940768084627 0.605412699002467 EGFR 1 GO:0009437 carnitine metabolic process 1/389 13/18722 0.238940768084627 0.605412699002467 CPT1C 1 GO:0009650 UV protection 1/389 13/18722 0.238940768084627 0.605412699002467 SCARA3 1 GO:0010635 regulation of mitochondrial fusion 1/389 13/18722 0.238940768084627 0.605412699002467 TFRC 1 GO:0010755 regulation of plasminogen activation 1/389 13/18722 0.238940768084627 0.605412699002467 SERPINE2 1 GO:0010960 magnesium ion homeostasis 1/389 13/18722 0.238940768084627 0.605412699002467 EGFR 1 GO:0016078 tRNA catabolic process 1/389 13/18722 0.238940768084627 0.605412699002467 ELAC2 1 GO:0021514 ventral spinal cord interneuron differentiation 1/389 13/18722 0.238940768084627 0.605412699002467 GLI3 1 GO:0021554 optic nerve development 1/389 13/18722 0.238940768084627 0.605412699002467 GLI3 1 GO:0021681 cerebellar granular layer development 1/389 13/18722 0.238940768084627 0.605412699002467 SERPINE2 1 GO:0021859 pyramidal neuron differentiation 1/389 13/18722 0.238940768084627 0.605412699002467 FGFR2 1 GO:0031272 regulation of pseudopodium assembly 1/389 13/18722 0.238940768084627 0.605412699002467 CDC42EP4 1 GO:0031274 positive regulation of pseudopodium assembly 1/389 13/18722 0.238940768084627 0.605412699002467 CDC42EP4 1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 1/389 13/18722 0.238940768084627 0.605412699002467 TRIB1 1 GO:0033689 negative regulation of osteoblast proliferation 1/389 13/18722 0.238940768084627 0.605412699002467 PLXNB1 1 GO:0034112 positive regulation of homotypic cell-cell adhesion 1/389 13/18722 0.238940768084627 0.605412699002467 IL6ST 1 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway 1/389 13/18722 0.238940768084627 0.605412699002467 RAB7B 1 GO:0034497 protein localization to phagophore assembly site 1/389 13/18722 0.238940768084627 0.605412699002467 TRAPPC8 1 GO:0035845 photoreceptor cell outer segment organization 1/389 13/18722 0.238940768084627 0.605412699002467 AHI1 1 GO:0042659 regulation of cell fate specification 1/389 13/18722 0.238940768084627 0.605412699002467 ESRP1 1 GO:0046415 urate metabolic process 1/389 13/18722 0.238940768084627 0.605412699002467 SLC22A11 1 GO:0051481 negative regulation of cytosolic calcium ion concentration 1/389 13/18722 0.238940768084627 0.605412699002467 LRP1 1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore 1/389 13/18722 0.238940768084627 0.605412699002467 RACGAP1 1 GO:0060100 positive regulation of phagocytosis, engulfment 1/389 13/18722 0.238940768084627 0.605412699002467 ANO6 1 GO:0060707 trophoblast giant cell differentiation 1/389 13/18722 0.238940768084627 0.605412699002467 NR2F2 1 GO:0070254 mucus secretion 1/389 13/18722 0.238940768084627 0.605412699002467 EGFR 1 GO:0071696 ectodermal placode development 1/389 13/18722 0.238940768084627 0.605412699002467 NRP1 1 GO:0072578 neurotransmitter-gated ion channel clustering 1/389 13/18722 0.238940768084627 0.605412699002467 SLC7A11 1 GO:0072710 response to hydroxyurea 1/389 13/18722 0.238940768084627 0.605412699002467 BLM 1 GO:0097154 GABAergic neuron differentiation 1/389 13/18722 0.238940768084627 0.605412699002467 RAC3 1 GO:0098814 spontaneous synaptic transmission 1/389 13/18722 0.238940768084627 0.605412699002467 SYT1 1 GO:0106074 aminoacyl-tRNA metabolism involved in translational fidelity 1/389 13/18722 0.238940768084627 0.605412699002467 TARS2 1 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response 1/389 13/18722 0.238940768084627 0.605412699002467 XBP1 1 GO:1900272 negative regulation of long-term synaptic potentiation 1/389 13/18722 0.238940768084627 0.605412699002467 ABL1 1 GO:1901096 regulation of autophagosome maturation 1/389 13/18722 0.238940768084627 0.605412699002467 CLN3 1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 1/389 13/18722 0.238940768084627 0.605412699002467 STK3 1 GO:1903977 positive regulation of glial cell migration 1/389 13/18722 0.238940768084627 0.605412699002467 LRP1 1 GO:1905155 positive regulation of membrane invagination 1/389 13/18722 0.238940768084627 0.605412699002467 ANO6 1 GO:0002790 peptide secretion 7/389 242/18722 0.239477816915767 0.605412699002467 LRP5/GJA1/LRP1/HMGCR/SLC16A1/CAMK2G/EGFR 7 GO:0006304 DNA modification 4/389 120/18722 0.239480812794322 0.605412699002467 DNMT3A/TDG/EZH2/HELLS 4 GO:0071774 response to fibroblast growth factor 4/389 120/18722 0.239480812794322 0.605412699002467 ELK1/KDM5B/FGFR2/GPC1 4 GO:0030850 prostate gland development 2/389 45/18722 0.240040242050334 0.605412699002467 GLI3/FGFR2 2 GO:0042551 neuron maturation 2/389 45/18722 0.240040242050334 0.605412699002467 SRRM4/RAC3 2 GO:0043038 amino acid activation 2/389 45/18722 0.240040242050334 0.605412699002467 TARS2/HARS2 2 GO:0045910 negative regulation of DNA recombination 2/389 45/18722 0.240040242050334 0.605412699002467 MAGEF1/BLM 2 GO:0046189 phenol-containing compound biosynthetic process 2/389 45/18722 0.240040242050334 0.605412699002467 SLC7A11/RAPGEF2 2 GO:0048538 thymus development 2/389 45/18722 0.240040242050334 0.605412699002467 EPHB3/ABL1 2 GO:0060421 positive regulation of heart growth 2/389 45/18722 0.240040242050334 0.605412699002467 YAP1/FGFR2 2 GO:0098534 centriole assembly 2/389 45/18722 0.240040242050334 0.605412699002467 CEP76/CEP44 2 GO:1904646 cellular response to amyloid-beta 2/389 45/18722 0.240040242050334 0.605412699002467 GJA1/LRP1 2 GO:0002312 B cell activation involved in immune response 3/389 82/18722 0.242749367592745 0.609236698675485 TFRC/ABL1/XBP1 3 GO:0060395 SMAD protein signal transduction 3/389 82/18722 0.242749367592745 0.609236698675485 PBLD/PPARG/LRP1 3 GO:0003205 cardiac chamber development 5/389 161/18722 0.243866074467347 0.609236698675485 LRP2/ADAMTS1/NRP1/FGFR2/FHL2 5 GO:0042177 negative regulation of protein catabolic process 4/389 121/18722 0.243977757546605 0.609236698675485 LRIG2/HMGCR/SERPINE2/EGFR 4 GO:0043500 muscle adaptation 4/389 121/18722 0.243977757546605 0.609236698675485 DAG1/CAMK2G/EZH2/IL6ST 4 GO:0019722 calcium-mediated signaling 6/389 202/18722 0.244255263177199 0.609236698675485 PDK2/ACKR2/CHERP/DMD/FHL2/EGFR 6 GO:0090087 regulation of peptide transport 6/389 202/18722 0.244255263177199 0.609236698675485 LRP5/GJA1/LRP1/HMGCR/SLC16A1/EGFR 6 GO:0051494 negative regulation of cytoskeleton organization 5/389 162/18722 0.247742132895496 0.609236698675485 MET/TJP1/KANK4/FKBP4/LIMA1 5 GO:0006383 transcription by RNA polymerase III 2/389 46/18722 0.247761127051579 0.609236698675485 POLR3F/CEBPA 2 GO:0043616 keratinocyte proliferation 2/389 46/18722 0.247761127051579 0.609236698675485 YAP1/FGFR2 2 GO:0044818 mitotic G2/M transition checkpoint 2/389 46/18722 0.247761127051579 0.609236698675485 FZR1/BLM 2 GO:0055010 ventricular cardiac muscle tissue morphogenesis 2/389 46/18722 0.247761127051579 0.609236698675485 LRP2/FGFR2 2 GO:0060976 coronary vasculature development 2/389 46/18722 0.247761127051579 0.609236698675485 LRP2/NRP1 2 GO:0061462 protein localization to lysosome 2/389 46/18722 0.247761127051579 0.609236698675485 HGS/SCARB2 2 GO:0051208 sequestering of calcium ion 4/389 122/18722 0.248493588123656 0.609236698675485 ATP7B/ABL1/CHERP/DMD 4 GO:0071322 cellular response to carbohydrate stimulus 5/389 163/18722 0.251634094837057 0.609236698675485 UNC13B/LRP5/LRP1/HMGCR/XBP1 5 GO:0031668 cellular response to extracellular stimulus 7/389 246/18722 0.251952109871642 0.609236698675485 CTSV/PDK2/TRIM24/SIK2/SLC2A1/SKP2/XBP1 7 GO:0071214 cellular response to abiotic stimulus 9/389 331/18722 0.252229361510746 0.609236698675485 ELK1/GJA1/DAG1/YAP1/CLN3/PCNA/BLM/SLC2A1/EGFR 9 GO:0104004 cellular response to environmental stimulus 9/389 331/18722 0.252229361510746 0.609236698675485 ELK1/GJA1/DAG1/YAP1/CLN3/PCNA/BLM/SLC2A1/EGFR 9 GO:0032508 DNA duplex unwinding 3/389 84/18722 0.253894379051049 0.609236698675485 WRNIP1/BLM/MCM5 3 GO:0000212 meiotic spindle organization 1/389 14/18722 0.254764812192547 0.609236698675485 ASPM 1 GO:0006287 base-excision repair, gap-filling 1/389 14/18722 0.254764812192547 0.609236698675485 PCNA 1 GO:0007100 mitotic centrosome separation 1/389 14/18722 0.254764812192547 0.609236698675485 KIF11 1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity 1/389 14/18722 0.254764812192547 0.609236698675485 PRLR 1 GO:0007638 mechanosensory behavior 1/389 14/18722 0.254764812192547 0.609236698675485 SLC1A3 1 GO:0010457 centriole-centriole cohesion 1/389 14/18722 0.254764812192547 0.609236698675485 CEP44 1 GO:0010839 negative regulation of keratinocyte proliferation 1/389 14/18722 0.254764812192547 0.609236698675485 FGFR2 1 GO:0014874 response to stimulus involved in regulation of muscle adaptation 1/389 14/18722 0.254764812192547 0.609236698675485 DAG1 1 GO:0022038 corpus callosum development 1/389 14/18722 0.254764812192547 0.609236698675485 EPHB3 1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway 1/389 14/18722 0.254764812192547 0.609236698675485 HGS 1 GO:0031115 negative regulation of microtubule polymerization 1/389 14/18722 0.254764812192547 0.609236698675485 FKBP4 1 GO:0033605 positive regulation of catecholamine secretion 1/389 14/18722 0.254764812192547 0.609236698675485 SYT1 1 GO:0034111 negative regulation of homotypic cell-cell adhesion 1/389 14/18722 0.254764812192547 0.609236698675485 SERPINE2 1 GO:0035437 maintenance of protein localization in endoplasmic reticulum 1/389 14/18722 0.254764812192547 0.609236698675485 GJA1 1 GO:0036151 phosphatidylcholine acyl-chain remodeling 1/389 14/18722 0.254764812192547 0.609236698675485 MBOAT7 1 GO:0038183 bile acid signaling pathway 1/389 14/18722 0.254764812192547 0.609236698675485 HMGCR 1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 1/389 14/18722 0.254764812192547 0.609236698675485 SPRED2 1 GO:0046462 monoacylglycerol metabolic process 1/389 14/18722 0.254764812192547 0.609236698675485 ABHD12 1 GO:0047484 regulation of response to osmotic stress 1/389 14/18722 0.254764812192547 0.609236698675485 CLN3 1 GO:0048172 regulation of short-term neuronal synaptic plasticity 1/389 14/18722 0.254764812192547 0.609236698675485 CLN3 1 GO:0048368 lateral mesoderm development 1/389 14/18722 0.254764812192547 0.609236698675485 YAP1 1 GO:0048681 negative regulation of axon regeneration 1/389 14/18722 0.254764812192547 0.609236698675485 LRIG2 1 GO:0051645 Golgi localization 1/389 14/18722 0.254764812192547 0.609236698675485 STK25 1 GO:0051764 actin crosslink formation 1/389 14/18722 0.254764812192547 0.609236698675485 GAS2L3 1 GO:0060080 inhibitory postsynaptic potential 1/389 14/18722 0.254764812192547 0.609236698675485 UNC13B 1 GO:0061043 regulation of vascular wound healing 1/389 14/18722 0.254764812192547 0.609236698675485 XBP1 1 GO:0070141 response to UV-A 1/389 14/18722 0.254764812192547 0.609236698675485 EGFR 1 GO:0070986 left/right axis specification 1/389 14/18722 0.254764812192547 0.609236698675485 AHI1 1 GO:0071236 cellular response to antibiotic 1/389 14/18722 0.254764812192547 0.609236698675485 EZH2 1 GO:0072160 nephron tubule epithelial cell differentiation 1/389 14/18722 0.254764812192547 0.609236698675485 YAP1 1 GO:0072176 nephric duct development 1/389 14/18722 0.254764812192547 0.609236698675485 AHI1 1 GO:0072531 pyrimidine-containing compound transmembrane transport 1/389 14/18722 0.254764812192547 0.609236698675485 SLC19A3 1 GO:0090281 negative regulation of calcium ion import 1/389 14/18722 0.254764812192547 0.609236698675485 TRIM27 1 GO:0098734 macromolecule depalmitoylation 1/389 14/18722 0.254764812192547 0.609236698675485 ABHD12 1 GO:1902036 regulation of hematopoietic stem cell differentiation 1/389 14/18722 0.254764812192547 0.609236698675485 ABL1 1 GO:1902916 positive regulation of protein polyubiquitination 1/389 14/18722 0.254764812192547 0.609236698675485 SKP2 1 GO:1905049 negative regulation of metallopeptidase activity 1/389 14/18722 0.254764812192547 0.609236698675485 LRP1 1 GO:1905208 negative regulation of cardiocyte differentiation 1/389 14/18722 0.254764812192547 0.609236698675485 EGFR 1 GO:0031098 stress-activated protein kinase signaling cascade 7/389 247/18722 0.255101237979807 0.609236698675485 MARVELD3/STK25/HMGCR/TRIB1/IRAK4/STK3/EGFR 7 GO:0007595 lactation 2/389 47/18722 0.255490041435146 0.609236698675485 PRLR/XBP1 2 GO:0010761 fibroblast migration 2/389 47/18722 0.255490041435146 0.609236698675485 CLN3/PTK2 2 GO:0031641 regulation of myelination 2/389 47/18722 0.255490041435146 0.609236698675485 DAG1/CYFIP1 2 GO:0042311 vasodilation 2/389 47/18722 0.255490041435146 0.609236698675485 GJA1/EGFR 2 GO:0045646 regulation of erythrocyte differentiation 2/389 47/18722 0.255490041435146 0.609236698675485 ACVR2A/RBFOX2 2 GO:0047496 vesicle transport along microtubule 2/389 47/18722 0.255490041435146 0.609236698675485 CLN3/DYNC1H1 2 GO:0048483 autonomic nervous system development 2/389 47/18722 0.255490041435146 0.609236698675485 FZD3/NRP1 2 GO:0051489 regulation of filopodium assembly 2/389 47/18722 0.255490041435146 0.609236698675485 NRP1/CLN3 2 GO:0050680 negative regulation of epithelial cell proliferation 5/389 164/18722 0.255541414227748 0.609236698675485 MARVELD3/PPARG/NR2F2/GJA1/FGFR2 5 GO:0050806 positive regulation of synaptic transmission 5/389 164/18722 0.255541414227748 0.609236698675485 SYT1/SLC1A3/ABL1/SERPINE2/EGFR 5 GO:0044282 small molecule catabolic process 10/389 376/18722 0.257367726148285 0.609236698675485 SYNJ2/CPT1C/SLC27A2/MPST/LRP5/BCKDHB/BLMH/ENOSF1/GLDC/SHMT1 10 GO:0023061 signal release 12/389 463/18722 0.257416721110962 0.609236698675485 UNC13B/SYT1/LRP5/GJA1/WLS/LRP1/KDM5B/RAB11FIP3/HMGCR/SLC16A1/CAMK2G/EGFR 12 GO:0007368 determination of left/right symmetry 4/389 124/18722 0.257578428720472 0.609236698675485 ARL6/ACVR2A/GALNT11/AHI1 4 GO:0032102 negative regulation of response to external stimulus 11/389 420/18722 0.258883846595232 0.609236698675485 PLAU/SEMA4G/SEMA6A/PPARG/GJA1/LRIG2/NRP1/CLDN3/HMGCR/SERPINE2/TRIB1 11 GO:0050796 regulation of insulin secretion 5/389 165/18722 0.259463545555023 0.609236698675485 LRP5/GJA1/LRP1/HMGCR/SLC16A1 5 GO:0072384 organelle transport along microtubule 3/389 85/18722 0.259494260304874 0.609236698675485 WASF1/CLN3/DYNC1H1 3 GO:0010632 regulation of epithelial cell migration 8/389 292/18722 0.262873931508797 0.609236698675485 MET/MARVELD3/PPARG/NR2F2/NRP1/DOCK5/ABL1/PTK2 8 GO:0006111 regulation of gluconeogenesis 2/389 48/18722 0.263223328384211 0.609236698675485 PDK2/WDR5 2 GO:0032527 protein exit from endoplasmic reticulum 2/389 48/18722 0.263223328384211 0.609236698675485 TMEM30B/TM9SF4 2 GO:0045005 DNA-dependent DNA replication maintenance of fidelity 2/389 48/18722 0.263223328384211 0.609236698675485 PCNA/BLM 2 GO:0097720 calcineurin-mediated signaling 2/389 48/18722 0.263223328384211 0.609236698675485 CHERP/FHL2 2 GO:0060538 skeletal muscle organ development 5/389 166/18722 0.263399944061536 0.609236698675485 NR2F2/DAG1/HMGCR/DMD/GPC1 5 GO:1902904 negative regulation of supramolecular fiber organization 5/389 166/18722 0.263399944061536 0.609236698675485 MET/TJP1/KANK4/FKBP4/LIMA1 5 GO:0006493 protein O-linked glycosylation 3/389 86/18722 0.265110301839626 0.609236698675485 TMTC2/TMTC3/GALNT11 3 GO:0022406 membrane docking 3/389 86/18722 0.265110301839626 0.609236698675485 UNC13B/SYT1/CLN3 3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 5/389 167/18722 0.267350065944053 0.609236698675485 DSC3/CDH1/PCDHGA10/FAT1/TENM3 5 GO:0007254 JNK cascade 5/389 167/18722 0.267350065944053 0.609236698675485 MARVELD3/TRIB1/IRAK4/STK3/EGFR 5 GO:0000478 endonucleolytic cleavage involved in rRNA processing 1/389 15/18722 0.270260668941377 0.609236698675485 RCL1 1 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/389 15/18722 0.270260668941377 0.609236698675485 RCL1 1 GO:0001325 formation of extrachromosomal circular DNA 1/389 15/18722 0.270260668941377 0.609236698675485 BLM 1 GO:0002070 epithelial cell maturation 1/389 15/18722 0.270260668941377 0.609236698675485 TFCP2L1 1 GO:0006268 DNA unwinding involved in DNA replication 1/389 15/18722 0.270260668941377 0.609236698675485 BLM 1 GO:0006271 DNA strand elongation involved in DNA replication 1/389 15/18722 0.270260668941377 0.609236698675485 PCNA 1 GO:0006878 cellular copper ion homeostasis 1/389 15/18722 0.270260668941377 0.609236698675485 ATP7B 1 GO:0007000 nucleolus organization 1/389 15/18722 0.270260668941377 0.609236698675485 SUV39H1 1 GO:0009083 branched-chain amino acid catabolic process 1/389 15/18722 0.270260668941377 0.609236698675485 BCKDHB 1 GO:0010273 detoxification of copper ion 1/389 15/18722 0.270260668941377 0.609236698675485 MT1A 1 GO:0010763 positive regulation of fibroblast migration 1/389 15/18722 0.270260668941377 0.609236698675485 PTK2 1 GO:0010889 regulation of sequestering of triglyceride 1/389 15/18722 0.270260668941377 0.609236698675485 PPARG 1 GO:0014733 regulation of skeletal muscle adaptation 1/389 15/18722 0.270260668941377 0.609236698675485 CAMK2G 1 GO:0018410 C-terminal protein amino acid modification 1/389 15/18722 0.270260668941377 0.609236698675485 ICMT 1 GO:0030852 regulation of granulocyte differentiation 1/389 15/18722 0.270260668941377 0.609236698675485 TRIB1 1 GO:0031269 pseudopodium assembly 1/389 15/18722 0.270260668941377 0.609236698675485 CDC42EP4 1 GO:0032486 Rap protein signal transduction 1/389 15/18722 0.270260668941377 0.609236698675485 RAPGEF2 1 GO:0032897 negative regulation of viral transcription 1/389 15/18722 0.270260668941377 0.609236698675485 TRIM27 1 GO:0033599 regulation of mammary gland epithelial cell proliferation 1/389 15/18722 0.270260668941377 0.609236698675485 KDM5B 1 GO:0035435 phosphate ion transmembrane transport 1/389 15/18722 0.270260668941377 0.609236698675485 SLC25A11 1 GO:0036124 histone H3-K9 trimethylation 1/389 15/18722 0.270260668941377 0.609236698675485 SUV39H1 1 GO:0042074 cell migration involved in gastrulation 1/389 15/18722 0.270260668941377 0.609236698675485 LRP5 1 GO:0042159 lipoprotein catabolic process 1/389 15/18722 0.270260668941377 0.609236698675485 ABHD12 1 GO:0042754 negative regulation of circadian rhythm 1/389 15/18722 0.270260668941377 0.609236698675485 SUV39H1 1 GO:0042976 activation of Janus kinase activity 1/389 15/18722 0.270260668941377 0.609236698675485 PRLR 1 GO:0043584 nose development 1/389 15/18722 0.270260668941377 0.609236698675485 GLI3 1 GO:0043981 histone H4-K5 acetylation 1/389 15/18722 0.270260668941377 0.609236698675485 WDR5 1 GO:0043982 histone H4-K8 acetylation 1/389 15/18722 0.270260668941377 0.609236698675485 WDR5 1 GO:0045176 apical protein localization 1/389 15/18722 0.270260668941377 0.609236698675485 JAM3 1 GO:0045346 regulation of MHC class II biosynthetic process 1/389 15/18722 0.270260668941377 0.609236698675485 XBP1 1 GO:0045986 negative regulation of smooth muscle contraction 1/389 15/18722 0.270260668941377 0.609236698675485 DOCK5 1 GO:0048308 organelle inheritance 1/389 15/18722 0.270260668941377 0.609236698675485 STK25 1 GO:0048313 Golgi inheritance 1/389 15/18722 0.270260668941377 0.609236698675485 STK25 1 GO:0048569 post-embryonic animal organ development 1/389 15/18722 0.270260668941377 0.609236698675485 FZD5 1 GO:0050746 regulation of lipoprotein metabolic process 1/389 15/18722 0.270260668941377 0.609236698675485 ITGAV 1 GO:0051299 centrosome separation 1/389 15/18722 0.270260668941377 0.609236698675485 KIF11 1 GO:0051315 attachment of mitotic spindle microtubules to kinetochore 1/389 15/18722 0.270260668941377 0.609236698675485 CENPE 1 GO:0051775 response to redox state 1/389 15/18722 0.270260668941377 0.609236698675485 SLC7A11 1 GO:0055012 ventricular cardiac muscle cell differentiation 1/389 15/18722 0.270260668941377 0.609236698675485 FHL2 1 GO:0060099 regulation of phagocytosis, engulfment 1/389 15/18722 0.270260668941377 0.609236698675485 ANO6 1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport 1/389 15/18722 0.270260668941377 0.609236698675485 GAS1 1 GO:0070071 proton-transporting two-sector ATPase complex assembly 1/389 15/18722 0.270260668941377 0.609236698675485 TM9SF4 1 GO:0070207 protein homotrimerization 1/389 15/18722 0.270260668941377 0.609236698675485 SIGMAR1 1 GO:0070831 basement membrane assembly 1/389 15/18722 0.270260668941377 0.609236698675485 DAG1 1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade 1/389 15/18722 0.270260668941377 0.609236698675485 FHL2 1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade 1/389 15/18722 0.270260668941377 0.609236698675485 CHERP 1 GO:0071474 cellular hyperosmotic response 1/389 15/18722 0.270260668941377 0.609236698675485 SLC2A1 1 GO:0090110 COPII-coated vesicle cargo loading 1/389 15/18722 0.270260668941377 0.609236698675485 SEC24C 1 GO:0090656 t-circle formation 1/389 15/18722 0.270260668941377 0.609236698675485 BLM 1 GO:0090737 telomere maintenance via telomere trimming 1/389 15/18722 0.270260668941377 0.609236698675485 BLM 1 GO:0106057 negative regulation of calcineurin-mediated signaling 1/389 15/18722 0.270260668941377 0.609236698675485 FHL2 1 GO:0106058 positive regulation of calcineurin-mediated signaling 1/389 15/18722 0.270260668941377 0.609236698675485 CHERP 1 GO:0140374 antiviral innate immune response 1/389 15/18722 0.270260668941377 0.609236698675485 ATAD3A 1 GO:0150011 regulation of neuron projection arborization 1/389 15/18722 0.270260668941377 0.609236698675485 MYO9A 1 GO:1901660 calcium ion export 1/389 15/18722 0.270260668941377 0.609236698675485 SLC35G1 1 GO:1901836 regulation of transcription of nucleolar large rRNA by RNA polymerase I 1/389 15/18722 0.270260668941377 0.609236698675485 IPPK 1 GO:1902018 negative regulation of cilium assembly 1/389 15/18722 0.270260668941377 0.609236698675485 YAP1 1 GO:1903543 positive regulation of exosomal secretion 1/389 15/18722 0.270260668941377 0.609236698675485 HGS 1 GO:1904380 endoplasmic reticulum mannose trimming 1/389 15/18722 0.270260668941377 0.609236698675485 UGGT2 1 GO:1904424 regulation of GTP binding 1/389 15/18722 0.270260668941377 0.609236698675485 MET 1 GO:1905288 vascular associated smooth muscle cell apoptotic process 1/389 15/18722 0.270260668941377 0.609236698675485 PPARG 1 GO:1905459 regulation of vascular associated smooth muscle cell apoptotic process 1/389 15/18722 0.270260668941377 0.609236698675485 PPARG 1 GO:1990169 stress response to copper ion 1/389 15/18722 0.270260668941377 0.609236698675485 MT1A 1 GO:1990822 basic amino acid transmembrane transport 1/389 15/18722 0.270260668941377 0.609236698675485 SLC38A9 1 GO:2000052 positive regulation of non-canonical Wnt signaling pathway 1/389 15/18722 0.270260668941377 0.609236698675485 ABL1 1 GO:2000104 negative regulation of DNA-dependent DNA replication 1/389 15/18722 0.270260668941377 0.609236698675485 BLM 1 GO:2000345 regulation of hepatocyte proliferation 1/389 15/18722 0.270260668941377 0.609236698675485 XBP1 1 GO:2001028 positive regulation of endothelial cell chemotaxis 1/389 15/18722 0.270260668941377 0.609236698675485 MET 1 GO:0016101 diterpenoid metabolic process 3/389 87/18722 0.27074096624032 0.609236698675485 LRP2/LRP1/EGFR 3 GO:0019915 lipid storage 3/389 87/18722 0.27074096624032 0.609236698675485 CDS1/PPARG/ITGAV 3 GO:1901606 alpha-amino acid catabolic process 3/389 87/18722 0.27074096624032 0.609236698675485 BLMH/GLDC/SHMT1 3 GO:0000959 mitochondrial RNA metabolic process 2/389 49/18722 0.270957478818655 0.609236698675485 TARS2/ELAC2 2 GO:0008038 neuron recognition 2/389 49/18722 0.270957478818655 0.609236698675485 EPHB3/NRP1 2 GO:0009395 phospholipid catabolic process 2/389 49/18722 0.270957478818655 0.609236698675485 PLBD1/ABHD12 2 GO:0009994 oocyte differentiation 2/389 49/18722 0.270957478818655 0.609236698675485 LGR5/ZFX 2 GO:0010823 negative regulation of mitochondrion organization 2/389 49/18722 0.270957478818655 0.609236698675485 PPARG/TFRC 2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 2/389 49/18722 0.270957478818655 0.609236698675485 PPARG/ACVR2A 2 GO:0021695 cerebellar cortex development 2/389 49/18722 0.270957478818655 0.609236698675485 SERPINE2/EZH2 2 GO:0030195 negative regulation of blood coagulation 2/389 49/18722 0.270957478818655 0.609236698675485 PLAU/SERPINE2 2 GO:0030225 macrophage differentiation 2/389 49/18722 0.270957478818655 0.609236698675485 TRIB1/CEBPA 2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 2/389 49/18722 0.270957478818655 0.609236698675485 CUL2/SKP2 2 GO:0035088 establishment or maintenance of apical/basal cell polarity 2/389 49/18722 0.270957478818655 0.609236698675485 MYO9A/FAT1 2 GO:0042461 photoreceptor cell development 2/389 49/18722 0.270957478818655 0.609236698675485 ARL3/AHI1 2 GO:0051445 regulation of meiotic cell cycle 2/389 49/18722 0.270957478818655 0.609236698675485 ASPM/FZR1 2 GO:0052372 modulation by symbiont of entry into host 2/389 49/18722 0.270957478818655 0.609236698675485 TRIM27/ITGAV 2 GO:0060964 regulation of gene silencing by miRNA 2/389 49/18722 0.270957478818655 0.609236698675485 PPARG/EGFR 2 GO:0060986 endocrine hormone secretion 2/389 49/18722 0.270957478818655 0.609236698675485 GJA1/RAB11FIP3 2 GO:0061245 establishment or maintenance of bipolar cell polarity 2/389 49/18722 0.270957478818655 0.609236698675485 MYO9A/FAT1 2 GO:0072666 establishment of protein localization to vacuole 2/389 49/18722 0.270957478818655 0.609236698675485 HGS/SCARB2 2 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 2/389 49/18722 0.270957478818655 0.609236698675485 ADAMTS1/GJA1 2 GO:0007568 aging 9/389 339/18722 0.274097917595072 0.61480616284846 COL4A2/CTSV/DAG1/DNMT3A/LRP1/TFCP2L1/ABL1/HMGCR/FZR1 9 GO:0009743 response to carbohydrate 7/389 253/18722 0.274231234892293 0.61480616284846 UNC13B/CTSV/LRP5/GJA1/LRP1/HMGCR/XBP1 7 GO:0097305 response to alcohol 7/389 253/18722 0.274231234892293 0.61480616284846 DAG1/CDH1/DNMT3A/CLDN3/FGFR2/HMGCR/BLM 7 GO:0014706 striated muscle tissue development 10/389 384/18722 0.278032292240033 0.61480616284846 LRP2/NR2F2/GJA1/YAP1/FGFR2/HMGCR/DMD/SGCB/FHL2/GPC1 10 GO:0042692 muscle cell differentiation 10/389 384/18722 0.278032292240033 0.61480616284846 MMP14/FGFR2/ANKRD17/MYOF/EZH2/DMD/SGCB/FHL2/BHLHE41/XBP1 10 GO:0002639 positive regulation of immunoglobulin production 2/389 50/18722 0.278689126861471 0.61480616284846 TFRC/XBP1 2 GO:0038093 Fc receptor signaling pathway 2/389 50/18722 0.278689126861471 0.61480616284846 ABL1/PTK2 2 GO:0043628 ncRNA 3'-end processing 2/389 50/18722 0.278689126861471 0.61480616284846 INTS1/ELAC2 2 GO:0050873 brown fat cell differentiation 2/389 50/18722 0.278689126861471 0.61480616284846 PEX11A/CEBPA 2 GO:0060688 regulation of morphogenesis of a branching structure 2/389 50/18722 0.278689126861471 0.61480616284846 ABL1/FGFR2 2 GO:1900047 negative regulation of hemostasis 2/389 50/18722 0.278689126861471 0.61480616284846 PLAU/SERPINE2 2 GO:1904036 negative regulation of epithelial cell apoptotic process 2/389 50/18722 0.278689126861471 0.61480616284846 YAP1/ABL1 2 GO:0031647 regulation of protein stability 8/389 298/18722 0.280644643079001 0.61480616284846 USP40/AAK1/TRIM24/OTUD3/CTNND1/P3H1/STK3/USP27X 8 GO:0045786 negative regulation of cell cycle 10/389 385/18722 0.280650199951131 0.61480616284846 GAS1/NR2F2/FZD3/DCUN1D3/ABL1/FZR1/BLM/CEBPA/EZH2/EGFR 10 GO:0051781 positive regulation of cell division 3/389 89/18722 0.282040136965052 0.61480616284846 MAP10/RACGAP1/FGFR2 3 GO:1900407 regulation of cellular response to oxidative stress 3/389 89/18722 0.282040136965052 0.61480616284846 MET/SLC7A11/AIFM2 3 GO:0051651 maintenance of location in cell 6/389 213/18722 0.282805660044026 0.61480616284846 ASPM/ATP7B/GJA1/ABL1/CHERP/DMD 6 GO:0031667 response to nutrient levels 12/389 474/18722 0.283069590178984 0.61480616284846 PPARG/CTSV/DNMT3A/BCKDHB/PDK2/TRIM24/HMGCR/SIK2/SLC16A1/SLC2A1/EGFR/XBP1 12 GO:0051048 negative regulation of secretion 5/389 171/18722 0.283276955319339 0.61480616284846 RHBDF1/GJA1/RAB11FIP3/HMGCR/ERBB3 5 GO:0006282 regulation of DNA repair 4/389 130/18722 0.285196690888641 0.61480616284846 WRNIP1/MAGEF1/PCNA/EGFR 4 GO:0007098 centrosome cycle 4/389 130/18722 0.285196690888641 0.61480616284846 KIF11/CEP76/SLC16A1/CEP44 4 GO:0015918 sterol transport 4/389 130/18722 0.285196690888641 0.61480616284846 PPARG/LRP1/SERAC1/LIMA1 4 GO:0042476 odontogenesis 4/389 130/18722 0.285196690888641 0.61480616284846 ACVR2A/GLI3/FGFR2/LAMA5 4 GO:0001977 renal system process involved in regulation of blood volume 1/389 16/18722 0.285435127688466 0.61480616284846 GJA1 1 GO:0002693 positive regulation of cellular extravasation 1/389 16/18722 0.285435127688466 0.61480616284846 JAM3 1 GO:0003084 positive regulation of systemic arterial blood pressure 1/389 16/18722 0.285435127688466 0.61480616284846 NR2F2 1 GO:0006349 regulation of gene expression by genetic imprinting 1/389 16/18722 0.285435127688466 0.61480616284846 DNMT3A 1 GO:0006555 methionine metabolic process 1/389 16/18722 0.285435127688466 0.61480616284846 MTHFD2L 1 GO:0006750 glutathione biosynthetic process 1/389 16/18722 0.285435127688466 0.61480616284846 SLC7A11 1 GO:0007635 chemosensory behavior 1/389 16/18722 0.285435127688466 0.61480616284846 TPBG 1 GO:0010225 response to UV-C 1/389 16/18722 0.285435127688466 0.61480616284846 DCUN1D3 1 GO:0010649 regulation of cell communication by electrical coupling 1/389 16/18722 0.285435127688466 0.61480616284846 GJA1 1 GO:0014819 regulation of skeletal muscle contraction 1/389 16/18722 0.285435127688466 0.61480616284846 DMD 1 GO:0017014 protein nitrosylation 1/389 16/18722 0.285435127688466 0.61480616284846 DMD 1 GO:0018119 peptidyl-cysteine S-nitrosylation 1/389 16/18722 0.285435127688466 0.61480616284846 DMD 1 GO:0021535 cell migration in hindbrain 1/389 16/18722 0.285435127688466 0.61480616284846 RBFOX2 1 GO:0021783 preganglionic parasympathetic fiber development 1/389 16/18722 0.285435127688466 0.61480616284846 NRP1 1 GO:0030033 microvillus assembly 1/389 16/18722 0.285435127688466 0.61480616284846 RAPGEF2 1 GO:0030540 female genitalia development 1/389 16/18722 0.285435127688466 0.61480616284846 LRP2 1 GO:0031268 pseudopodium organization 1/389 16/18722 0.285435127688466 0.61480616284846 CDC42EP4 1 GO:0032274 gonadotropin secretion 1/389 16/18722 0.285435127688466 0.61480616284846 GJA1 1 GO:0034116 positive regulation of heterotypic cell-cell adhesion 1/389 16/18722 0.285435127688466 0.61480616284846 GCNT2 1 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter 1/389 16/18722 0.285435127688466 0.61480616284846 EZH2 1 GO:0034393 positive regulation of smooth muscle cell apoptotic process 1/389 16/18722 0.285435127688466 0.61480616284846 PPARG 1 GO:0044849 estrous cycle 1/389 16/18722 0.285435127688466 0.61480616284846 PCNA 1 GO:0045342 MHC class II biosynthetic process 1/389 16/18722 0.285435127688466 0.61480616284846 XBP1 1 GO:0045651 positive regulation of macrophage differentiation 1/389 16/18722 0.285435127688466 0.61480616284846 TRIB1 1 GO:0045722 positive regulation of gluconeogenesis 1/389 16/18722 0.285435127688466 0.61480616284846 WDR5 1 GO:0046037 GMP metabolic process 1/389 16/18722 0.285435127688466 0.61480616284846 TJP2 1 GO:0048385 regulation of retinoic acid receptor signaling pathway 1/389 16/18722 0.285435127688466 0.61480616284846 EZH2 1 GO:0055089 fatty acid homeostasis 1/389 16/18722 0.285435127688466 0.61480616284846 XBP1 1 GO:0060330 regulation of response to interferon-gamma 1/389 16/18722 0.285435127688466 0.61480616284846 PPARG 1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway 1/389 16/18722 0.285435127688466 0.61480616284846 PPARG 1 GO:0060572 morphogenesis of an epithelial bud 1/389 16/18722 0.285435127688466 0.61480616284846 FGFR2 1 GO:0070242 thymocyte apoptotic process 1/389 16/18722 0.285435127688466 0.61480616284846 GLI3 1 GO:0070571 negative regulation of neuron projection regeneration 1/389 16/18722 0.285435127688466 0.61480616284846 LRIG2 1 GO:0071361 cellular response to ethanol 1/389 16/18722 0.285435127688466 0.61480616284846 DNMT3A 1 GO:0071391 cellular response to estrogen stimulus 1/389 16/18722 0.285435127688466 0.61480616284846 TRIM24 1 GO:0097428 protein maturation by iron-sulfur cluster transfer 1/389 16/18722 0.285435127688466 0.61480616284846 MAGEF1 1 GO:0099633 protein localization to postsynaptic specialization membrane 1/389 16/18722 0.285435127688466 0.61480616284846 DAG1 1 GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane 1/389 16/18722 0.285435127688466 0.61480616284846 DAG1 1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway 1/389 16/18722 0.285435127688466 0.61480616284846 SEMA6A 1 GO:1901163 regulation of trophoblast cell migration 1/389 16/18722 0.285435127688466 0.61480616284846 GJA1 1 GO:1901201 regulation of extracellular matrix assembly 1/389 16/18722 0.285435127688466 0.61480616284846 DAG1 1 GO:1902570 protein localization to nucleolus 1/389 16/18722 0.285435127688466 0.61480616284846 POLR1A 1 GO:1904862 inhibitory synapse assembly 1/389 16/18722 0.285435127688466 0.61480616284846 PLXNB1 1 GO:1905153 regulation of membrane invagination 1/389 16/18722 0.285435127688466 0.61480616284846 ANO6 1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway 1/389 16/18722 0.285435127688466 0.61480616284846 ABL1 1 GO:2000651 positive regulation of sodium ion transmembrane transporter activity 1/389 16/18722 0.285435127688466 0.61480616284846 DMD 1 GO:2001212 regulation of vasculogenesis 1/389 16/18722 0.285435127688466 0.61480616284846 RAPGEF2 1 GO:0009948 anterior/posterior axis specification 2/389 51/18722 0.286415045428992 0.61480616284846 FZD5/WLS 2 GO:0010874 regulation of cholesterol efflux 2/389 51/18722 0.286415045428992 0.61480616284846 PPARG/LRP1 2 GO:0014009 glial cell proliferation 2/389 51/18722 0.286415045428992 0.61480616284846 PRKCH/EGFR 2 GO:0046850 regulation of bone remodeling 2/389 51/18722 0.286415045428992 0.61480616284846 TFRC/EGFR 2 GO:0050982 detection of mechanical stimulus 2/389 51/18722 0.286415045428992 0.61480616284846 SERPINE2/PTK2 2 GO:0051293 establishment of spindle localization 2/389 51/18722 0.286415045428992 0.61480616284846 GJA1/DYNC1H1 2 GO:0071622 regulation of granulocyte chemotaxis 2/389 51/18722 0.286415045428992 0.61480616284846 JAM3/PTK2 2 GO:0001678 cellular glucose homeostasis 5/389 172/18722 0.287287583776484 0.615403319618747 UNC13B/LRP5/LRP1/HMGCR/XBP1 5 GO:0002028 regulation of sodium ion transport 3/389 90/18722 0.287705692336157 0.615403319618747 SERPINE2/PRSS8/DMD 3 GO:0032392 DNA geometric change 3/389 90/18722 0.287705692336157 0.615403319618747 WRNIP1/BLM/MCM5 3 GO:0042475 odontogenesis of dentin-containing tooth 3/389 90/18722 0.287705692336157 0.615403319618747 ACVR2A/GLI3/LAMA5 3 GO:0048477 oogenesis 3/389 90/18722 0.287705692336157 0.615403319618747 ASPM/LGR5/ZFX 3 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 3/389 90/18722 0.287705692336157 0.615403319618747 ADAMTS1/PPARG/GJA1 3 GO:0031669 cellular response to nutrient levels 6/389 215/18722 0.289961512957817 0.619864969376997 CTSV/PDK2/TRIM24/SIK2/SLC2A1/XBP1 6 GO:0045165 cell fate commitment 7/389 258/18722 0.290450040015947 0.620545574656215 GAS1/PPARG/NR2F2/GLI3/NRP1/FGFR2/ESRP1 7 GO:0001657 ureteric bud development 3/389 91/18722 0.293379969177262 0.624387270845681 GLI3/FGFR2/LAMA5 3 GO:1990874 vascular associated smooth muscle cell proliferation 3/389 91/18722 0.293379969177262 0.624387270845681 ADAMTS1/PPARG/GJA1 3 GO:0043090 amino acid import 2/389 52/18722 0.294132141941783 0.624387270845681 SLC7A11/SLC1A3 2 GO:0060071 Wnt signaling pathway, planar cell polarity pathway 2/389 52/18722 0.294132141941783 0.624387270845681 FZD3/ABL1 2 GO:0060147 regulation of posttranscriptional gene silencing 2/389 52/18722 0.294132141941783 0.624387270845681 PPARG/EGFR 2 GO:0001708 cell fate specification 3/389 92/18722 0.299061555483463 0.624387270845681 GLI3/NRP1/ESRP1 3 GO:0032465 regulation of cytokinesis 3/389 92/18722 0.299061555483463 0.624387270845681 MAP10/RACGAP1/RAB11FIP3 3 GO:0072163 mesonephric epithelium development 3/389 92/18722 0.299061555483463 0.624387270845681 GLI3/FGFR2/LAMA5 3 GO:0072164 mesonephric tubule development 3/389 92/18722 0.299061555483463 0.624387270845681 GLI3/FGFR2/LAMA5 3 GO:0009855 determination of bilateral symmetry 4/389 133/18722 0.299168883913664 0.624387270845681 ARL6/ACVR2A/GALNT11/AHI1 4 GO:0010565 regulation of cellular ketone metabolic process 4/389 133/18722 0.299168883913664 0.624387270845681 SLC7A11/PPARG/PDK2/CLN3 4 GO:0000097 sulfur amino acid biosynthetic process 1/389 17/18722 0.300294837692165 0.624387270845681 MTHFD2L 1 GO:0001829 trophectodermal cell differentiation 1/389 17/18722 0.300294837692165 0.624387270845681 YAP1 1 GO:0006577 amino-acid betaine metabolic process 1/389 17/18722 0.300294837692165 0.624387270845681 CPT1C 1 GO:0006744 ubiquinone biosynthetic process 1/389 17/18722 0.300294837692165 0.624387270845681 COQ9 1 GO:0007076 mitotic chromosome condensation 1/389 17/18722 0.300294837692165 0.624387270845681 SMC2 1 GO:0007351 tripartite regional subdivision 1/389 17/18722 0.300294837692165 0.624387270845681 FZD5 1 GO:0007379 segment specification 1/389 17/18722 0.300294837692165 0.624387270845681 COBL 1 GO:0008340 determination of adult lifespan 1/389 17/18722 0.300294837692165 0.624387270845681 TFCP2L1 1 GO:0008595 anterior/posterior axis specification, embryo 1/389 17/18722 0.300294837692165 0.624387270845681 FZD5 1 GO:0009084 glutamine family amino acid biosynthetic process 1/389 17/18722 0.300294837692165 0.624387270845681 CLN3 1 GO:0010470 regulation of gastrulation 1/389 17/18722 0.300294837692165 0.624387270845681 DAG1 1 GO:0010715 regulation of extracellular matrix disassembly 1/389 17/18722 0.300294837692165 0.624387270845681 LRP1 1 GO:0010831 positive regulation of myotube differentiation 1/389 17/18722 0.300294837692165 0.624387270845681 MMP14 1 GO:0016264 gap junction assembly 1/389 17/18722 0.300294837692165 0.624387270845681 GJA1 1 GO:0021513 spinal cord dorsal/ventral patterning 1/389 17/18722 0.300294837692165 0.624387270845681 GLI3 1 GO:0021756 striatum development 1/389 17/18722 0.300294837692165 0.624387270845681 SLC7A11 1 GO:0021924 cell proliferation in external granule layer 1/389 17/18722 0.300294837692165 0.624387270845681 PSMG1 1 GO:0021930 cerebellar granule cell precursor proliferation 1/389 17/18722 0.300294837692165 0.624387270845681 PSMG1 1 GO:0034349 glial cell apoptotic process 1/389 17/18722 0.300294837692165 0.624387270845681 PRKCH 1 GO:0035729 cellular response to hepatocyte growth factor stimulus 1/389 17/18722 0.300294837692165 0.624387270845681 NRP1 1 GO:0043950 positive regulation of cAMP-mediated signaling 1/389 17/18722 0.300294837692165 0.624387270845681 RAPGEF2 1 GO:0046855 inositol phosphate dephosphorylation 1/389 17/18722 0.300294837692165 0.624387270845681 SYNJ2 1 GO:0048339 paraxial mesoderm development 1/389 17/18722 0.300294837692165 0.624387270845681 YAP1 1 GO:0048532 anatomical structure arrangement 1/389 17/18722 0.300294837692165 0.624387270845681 NRP1 1 GO:0060033 anatomical structure regression 1/389 17/18722 0.300294837692165 0.624387270845681 LRP5 1 GO:0070206 protein trimerization 1/389 17/18722 0.300294837692165 0.624387270845681 SIGMAR1 1 GO:0070293 renal absorption 1/389 17/18722 0.300294837692165 0.624387270845681 CLDN4 1 GO:0071816 tail-anchored membrane protein insertion into ER membrane 1/389 17/18722 0.300294837692165 0.624387270845681 EMC1 1 GO:0072673 lamellipodium morphogenesis 1/389 17/18722 0.300294837692165 0.624387270845681 WASF1 1 GO:0090136 epithelial cell-cell adhesion 1/389 17/18722 0.300294837692165 0.624387270845681 ITGB5 1 GO:1901663 quinone biosynthetic process 1/389 17/18722 0.300294837692165 0.624387270845681 COQ9 1 GO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II 1/389 17/18722 0.300294837692165 0.624387270845681 PPARG 1 GO:1903541 regulation of exosomal secretion 1/389 17/18722 0.300294837692165 0.624387270845681 HGS 1 GO:1903830 magnesium ion transmembrane transport 1/389 17/18722 0.300294837692165 0.624387270845681 ZDHHC13 1 GO:2000696 regulation of epithelial cell differentiation involved in kidney development 1/389 17/18722 0.300294837692165 0.624387270845681 YAP1 1 GO:2000811 negative regulation of anoikis 1/389 17/18722 0.300294837692165 0.624387270845681 PTK2 1 GO:0001541 ovarian follicle development 2/389 53/18722 0.301837454153105 0.625810798917779 ZFX/MMP14 2 GO:0045806 negative regulation of endocytosis 2/389 53/18722 0.301837454153105 0.625810798917779 PROM2/ITGAV 2 GO:0050819 negative regulation of coagulation 2/389 53/18722 0.301837454153105 0.625810798917779 PLAU/SERPINE2 2 GO:0060966 regulation of gene silencing by RNA 2/389 53/18722 0.301837454153105 0.625810798917779 PPARG/EGFR 2 GO:1903202 negative regulation of oxidative stress-induced cell death 2/389 53/18722 0.301837454153105 0.625810798917779 MET/SLC7A11 2 GO:0009799 specification of symmetry 4/389 134/18722 0.303844976704002 0.628275771611785 ARL6/ACVR2A/GALNT11/AHI1 4 GO:0098727 maintenance of cell number 4/389 134/18722 0.303844976704002 0.628275771611785 ASPM/LRP5/YAP1/EZH2 4 GO:0097191 extrinsic apoptotic signaling pathway 6/389 219/18722 0.304382938420263 0.628275771611785 ITGA6/YAP1/NRP1/ERBB3/STK3/ITGAV 6 GO:2001020 regulation of response to DNA damage stimulus 6/389 219/18722 0.304382938420263 0.628275771611785 SPRED2/ABL1/WRNIP1/MAGEF1/PCNA/EGFR 6 GO:0007589 body fluid secretion 3/389 93/18722 0.304749064979777 0.628275771611785 PRLR/EGFR/XBP1 3 GO:0032755 positive regulation of interleukin-6 production 3/389 93/18722 0.304749064979777 0.628275771611785 RAB7B/SETD4/XBP1 3 GO:0033273 response to vitamin 3/389 93/18722 0.304749064979777 0.628275771611785 DNMT3A/TRIM24/EGFR 3 GO:0045185 maintenance of protein location 3/389 93/18722 0.304749064979777 0.628275771611785 LTBP1/GJA1/FBN2 3 GO:0060993 kidney morphogenesis 3/389 93/18722 0.304749064979777 0.628275771611785 GLI3/LAMA5/AHI1 3 GO:1901992 positive regulation of mitotic cell cycle phase transition 3/389 93/18722 0.304749064979777 0.628275771611785 ADAMTS1/ANKRD17/EGFR 3 GO:0050804 modulation of chemical synaptic transmission 11/389 439/18722 0.306077951197527 0.630211029747732 SLC7A11/LZTS1/SYT1/SLC1A3/CDH1/ABL1/CLN3/SERPINE2/CYFIP1/RAPGEF2/EGFR 11 GO:0001666 response to hypoxia 8/389 307/18722 0.307865528790576 0.630211029747732 PLAU/PLOD1/DNMT3A/CLDN3/MMP14/SUV39H1/TM9SF4/SLC2A1 8 GO:0002687 positive regulation of leukocyte migration 4/389 135/18722 0.308529085012562 0.630211029747732 JAM3/MMP14/PTK2/ANO6 4 GO:0099177 regulation of trans-synaptic signaling 11/389 440/18722 0.308624036836739 0.630211029747732 SLC7A11/LZTS1/SYT1/SLC1A3/CDH1/ABL1/CLN3/SERPINE2/CYFIP1/RAPGEF2/EGFR 11 GO:0014888 striated muscle adaptation 2/389 54/18722 0.309528146091933 0.630211029747732 CAMK2G/EZH2 2 GO:0032330 regulation of chondrocyte differentiation 2/389 54/18722 0.309528146091933 0.630211029747732 GLI3/ZNF219 2 GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II 2/389 54/18722 0.309528146091933 0.630211029747732 PPARG/TEAD1 2 GO:0002042 cell migration involved in sprouting angiogenesis 3/389 94/18722 0.310441137262174 0.630211029747732 EPHB4/NRP1/ABL1 3 GO:0072503 cellular divalent inorganic cation homeostasis 12/389 486/18722 0.311900089129082 0.630211029747732 SLC35G1/ATP7B/GJA1/LRP1/C19orf12/ACKR2/ABL1/CLN3/MT1A/CHERP/DMD/ITGAV 12 GO:0098876 vesicle-mediated transport to the plasma membrane 4/389 136/18722 0.313220421423712 0.630211029747732 CLN3/MICALL1/RAB11FIP3/ARL3 4 GO:0051480 regulation of cytosolic calcium ion concentration 9/389 353/18722 0.313589304171875 0.630211029747732 SLC35G1/GJA1/LRP1/ACKR2/ABL1/CLN3/CHERP/DMD/ITGAV 9 GO:0001956 positive regulation of neurotransmitter secretion 1/389 18/18722 0.314846310995439 0.630211029747732 SYT1 1 GO:0002076 osteoblast development 1/389 18/18722 0.314846310995439 0.630211029747732 LRP5 1 GO:0002544 chronic inflammatory response 1/389 18/18722 0.314846310995439 0.630211029747732 GJA1 1 GO:0003128 heart field specification 1/389 18/18722 0.314846310995439 0.630211029747732 LRP2 1 GO:0006085 acetyl-CoA biosynthetic process 1/389 18/18722 0.314846310995439 0.630211029747732 PDK2 1 GO:0006415 translational termination 1/389 18/18722 0.314846310995439 0.630211029747732 MTRF1L 1 GO:0010663 positive regulation of striated muscle cell apoptotic process 1/389 18/18722 0.314846310995439 0.630211029747732 HMGCR 1 GO:0010666 positive regulation of cardiac muscle cell apoptotic process 1/389 18/18722 0.314846310995439 0.630211029747732 HMGCR 1 GO:0015693 magnesium ion transport 1/389 18/18722 0.314846310995439 0.630211029747732 ZDHHC13 1 GO:0019184 nonribosomal peptide biosynthetic process 1/389 18/18722 0.314846310995439 0.630211029747732 SLC7A11 1 GO:0021511 spinal cord patterning 1/389 18/18722 0.314846310995439 0.630211029747732 GLI3 1 GO:0021534 cell proliferation in hindbrain 1/389 18/18722 0.314846310995439 0.630211029747732 PSMG1 1 GO:0030299 intestinal cholesterol absorption 1/389 18/18722 0.314846310995439 0.630211029747732 LIMA1 1 GO:0030728 ovulation 1/389 18/18722 0.314846310995439 0.630211029747732 ADAMTS1 1 GO:0030730 sequestering of triglyceride 1/389 18/18722 0.314846310995439 0.630211029747732 PPARG 1 GO:0031643 positive regulation of myelination 1/389 18/18722 0.314846310995439 0.630211029747732 DAG1 1 GO:0032785 negative regulation of DNA-templated transcription, elongation 1/389 18/18722 0.314846310995439 0.630211029747732 EZH2 1 GO:0033189 response to vitamin A 1/389 18/18722 0.314846310995439 0.630211029747732 DNMT3A 1 GO:0036507 protein demannosylation 1/389 18/18722 0.314846310995439 0.630211029747732 UGGT2 1 GO:0036508 protein alpha-1,2-demannosylation 1/389 18/18722 0.314846310995439 0.630211029747732 UGGT2 1 GO:0042790 nucleolar large rRNA transcription by RNA polymerase I 1/389 18/18722 0.314846310995439 0.630211029747732 IPPK 1 GO:0043116 negative regulation of vascular permeability 1/389 18/18722 0.314846310995439 0.630211029747732 FERMT2 1 GO:0043217 myelin maintenance 1/389 18/18722 0.314846310995439 0.630211029747732 EPB41L3 1 GO:0045116 protein neddylation 1/389 18/18722 0.314846310995439 0.630211029747732 DCUN1D3 1 GO:0045956 positive regulation of calcium ion-dependent exocytosis 1/389 18/18722 0.314846310995439 0.630211029747732 SYT1 1 GO:0046112 nucleobase biosynthetic process 1/389 18/18722 0.314846310995439 0.630211029747732 SHMT1 1 GO:0046838 phosphorylated carbohydrate dephosphorylation 1/389 18/18722 0.314846310995439 0.630211029747732 SYNJ2 1 GO:0048486 parasympathetic nervous system development 1/389 18/18722 0.314846310995439 0.630211029747732 NRP1 1 GO:0048643 positive regulation of skeletal muscle tissue development 1/389 18/18722 0.314846310995439 0.630211029747732 HMGCR 1 GO:0051382 kinetochore assembly 1/389 18/18722 0.314846310995439 0.630211029747732 CENPE 1 GO:0055070 copper ion homeostasis 1/389 18/18722 0.314846310995439 0.630211029747732 ATP7B 1 GO:0060008 Sertoli cell differentiation 1/389 18/18722 0.314846310995439 0.630211029747732 CTSV 1 GO:0060192 negative regulation of lipase activity 1/389 18/18722 0.314846310995439 0.630211029747732 ABL1 1 GO:0060391 positive regulation of SMAD protein signal transduction 1/389 18/18722 0.314846310995439 0.630211029747732 PPARG 1 GO:0060546 negative regulation of necroptotic process 1/389 18/18722 0.314846310995439 0.630211029747732 SLC25A4 1 GO:0060716 labyrinthine layer blood vessel development 1/389 18/18722 0.314846310995439 0.630211029747732 FZD5 1 GO:0061484 hematopoietic stem cell homeostasis 1/389 18/18722 0.314846310995439 0.630211029747732 ADGRG1 1 GO:0061687 detoxification of inorganic compound 1/389 18/18722 0.314846310995439 0.630211029747732 MT1A 1 GO:0072234 metanephric nephron tubule development 1/389 18/18722 0.314846310995439 0.630211029747732 YAP1 1 GO:1902001 fatty acid transmembrane transport 1/389 18/18722 0.314846310995439 0.630211029747732 SLC2A1 1 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus 1/389 18/18722 0.314846310995439 0.630211029747732 SEMA6A 1 GO:1902683 regulation of receptor localization to synapse 1/389 18/18722 0.314846310995439 0.630211029747732 DAG1 1 GO:0001936 regulation of endothelial cell proliferation 5/389 179/18722 0.315626122302096 0.630770929943766 EGFL7/PPARG/NR2F2/GJA1/NRP1 5 GO:0050764 regulation of phagocytosis 3/389 95/18722 0.316136437909454 0.630770929943766 LRP1/ITGAV/ANO6 3 GO:0022411 cellular component disassembly 11/389 443/18722 0.316293851191276 0.630770929943766 SPATA18/MMP15/FZD5/CTSV/LRP1/MMP14/CLN3/LAMC1/MTRF1L/SLC25A4/LIMA1 11 GO:0048285 organelle fission 12/389 488/18722 0.316778515577995 0.630770929943766 ASPM/MAP10/CENPE/PEX11A/PPARG/LRP5/KIF11/RACGAP1/COX10/MIEF2/FZR1/SMC2 12 GO:0051047 positive regulation of secretion 8/389 310/18722 0.317065917407895 0.630770929943766 UNC13B/SYT1/GJA1/WLS/LRP1/HGS/EGFR/XBP1 8 GO:0003229 ventricular cardiac muscle tissue development 2/389 55/18722 0.317201504117595 0.630770929943766 LRP2/FGFR2 2 GO:0006360 transcription by RNA polymerase I 2/389 55/18722 0.317201504117595 0.630770929943766 POLR1A/IPPK 2 GO:0042220 response to cocaine 2/389 55/18722 0.317201504117595 0.630770929943766 SLC1A3/DNMT3A 2 GO:0048016 inositol phosphate-mediated signaling 2/389 55/18722 0.317201504117595 0.630770929943766 CHERP/FHL2 2 GO:0051898 negative regulation of protein kinase B signaling 2/389 55/18722 0.317201504117595 0.630770929943766 DAG1/OTUD3 2 GO:0061614 pri-miRNA transcription by RNA polymerase II 2/389 55/18722 0.317201504117595 0.630770929943766 PPARG/TEAD1 2 GO:1905517 macrophage migration 2/389 55/18722 0.317201504117595 0.630770929943766 MMP14/PTK2 2 GO:0008203 cholesterol metabolic process 4/389 137/18722 0.317918206686381 0.631507461756662 LRP5/HMGCR/CEBPA/LIMA1 4 GO:0045471 response to ethanol 4/389 137/18722 0.317918206686381 0.631507461756662 DNMT3A/CLDN3/FGFR2/HMGCR 4 GO:0007033 vacuole organization 5/389 180/18722 0.319705929940681 0.631509322929352 RAB7B/SCARB2/TRAPPC8/CLN3/TMEM175 5 GO:0010721 negative regulation of cell development 5/389 180/18722 0.319705929940681 0.631509322929352 SEMA4G/SEMA6A/NRP1/CDKL3/RAPGEF2 5 GO:0001823 mesonephros development 3/389 96/18722 0.321833658567391 0.631509322929352 GLI3/FGFR2/LAMA5 3 GO:0035282 segmentation 3/389 96/18722 0.321833658567391 0.631509322929352 FZD5/COBL/NRP1 3 GO:0043648 dicarboxylic acid metabolic process 3/389 96/18722 0.321833658567391 0.631509322929352 SLC7A11/SHMT1/MTHFD2L 3 GO:0055017 cardiac muscle tissue growth 3/389 96/18722 0.321833658567391 0.631509322929352 GJA1/YAP1/FGFR2 3 GO:1904035 regulation of epithelial cell apoptotic process 3/389 96/18722 0.321833658567391 0.631509322929352 YAP1/ABL1/ANO6 3 GO:2001234 negative regulation of apoptotic signaling pathway 6/389 224/18722 0.322584553218227 0.631509322929352 ITGA6/YAP1/NRP1/ITGAV/HELLS/XBP1 6 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 4/389 138/18722 0.322621669908583 0.631509322929352 DCUN1D3/FZR1/SPRTN/SKP2 4 GO:0045766 positive regulation of angiogenesis 5/389 181/18722 0.323792048457321 0.631509322929352 EPHA1/TJP1/NRP1/ABL1/XBP1 5 GO:1904018 positive regulation of vasculature development 5/389 181/18722 0.323792048457321 0.631509322929352 EPHA1/TJP1/NRP1/ABL1/XBP1 5 GO:0001658 branching involved in ureteric bud morphogenesis 2/389 56/18722 0.324854933083148 0.631509322929352 GLI3/LAMA5 2 GO:0010518 positive regulation of phospholipase activity 2/389 56/18722 0.324854933083148 0.631509322929352 FGFR2/EGFR 2 GO:0045599 negative regulation of fat cell differentiation 2/389 56/18722 0.324854933083148 0.631509322929352 YAP1/FERMT2 2 GO:0046622 positive regulation of organ growth 2/389 56/18722 0.324854933083148 0.631509322929352 YAP1/FGFR2 2 GO:0090175 regulation of establishment of planar polarity 2/389 56/18722 0.324854933083148 0.631509322929352 FZD3/ABL1 2 GO:1904645 response to amyloid-beta 2/389 56/18722 0.324854933083148 0.631509322929352 GJA1/LRP1 2 GO:0010631 epithelial cell migration 9/389 357/18722 0.325102544925131 0.631509322929352 MET/MARVELD3/EPHB4/PPARG/NR2F2/NRP1/DOCK5/ABL1/PTK2 9 GO:0006364 rRNA processing 6/389 225/18722 0.326244474927774 0.631509322929352 RCL1/MRM1/SUV39H1/RPF1/WDR36/NSUN4 6 GO:0006721 terpenoid metabolic process 3/389 97/18722 0.327531517006448 0.631509322929352 LRP2/LRP1/EGFR 3 GO:0070167 regulation of biomineral tissue development 3/389 97/18722 0.327531517006448 0.631509322929352 ACVR2A/FBN2/ANO6 3 GO:0120162 positive regulation of cold-induced thermogenesis 3/389 97/18722 0.327531517006448 0.631509322929352 GJA1/DYNC1H1/PRLR 3 GO:0060537 muscle tissue development 10/389 403/18722 0.328870837812617 0.631509322929352 LRP2/NR2F2/GJA1/YAP1/FGFR2/HMGCR/DMD/SGCB/FHL2/GPC1 10 GO:0000729 DNA double-strand break processing 1/389 19/18722 0.329095925250292 0.631509322929352 BLM 1 GO:0002523 leukocyte migration involved in inflammatory response 1/389 19/18722 0.329095925250292 0.631509322929352 JAM3 1 GO:0006007 glucose catabolic process 1/389 19/18722 0.329095925250292 0.631509322929352 LRP5 1 GO:0006044 N-acetylglucosamine metabolic process 1/389 19/18722 0.329095925250292 0.631509322929352 EXTL2 1 GO:0006144 purine nucleobase metabolic process 1/389 19/18722 0.329095925250292 0.631509322929352 SHMT1 1 GO:0008356 asymmetric cell division 1/389 19/18722 0.329095925250292 0.631509322929352 ASPM 1 GO:0009081 branched-chain amino acid metabolic process 1/389 19/18722 0.329095925250292 0.631509322929352 BCKDHB 1 GO:0009223 pyrimidine deoxyribonucleotide catabolic process 1/389 19/18722 0.329095925250292 0.631509322929352 TDG 1 GO:0009226 nucleotide-sugar biosynthetic process 1/389 19/18722 0.329095925250292 0.631509322929352 PMM1 1 GO:0010544 negative regulation of platelet activation 1/389 19/18722 0.329095925250292 0.631509322929352 SERPINE2 1 GO:0010744 positive regulation of macrophage derived foam cell differentiation 1/389 19/18722 0.329095925250292 0.631509322929352 PRKCH 1 GO:0010759 positive regulation of macrophage chemotaxis 1/389 19/18722 0.329095925250292 0.631509322929352 PTK2 1 GO:0010885 regulation of cholesterol storage 1/389 19/18722 0.329095925250292 0.631509322929352 PPARG 1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling 1/389 19/18722 0.329095925250292 0.631509322929352 SERPINE2 1 GO:0016082 synaptic vesicle priming 1/389 19/18722 0.329095925250292 0.631509322929352 UNC13B 1 GO:0030011 maintenance of cell polarity 1/389 19/18722 0.329095925250292 0.631509322929352 DST 1 GO:0030050 vesicle transport along actin filament 1/389 19/18722 0.329095925250292 0.631509322929352 MYO1C 1 GO:0035313 wound healing, spreading of epidermal cells 1/389 19/18722 0.329095925250292 0.631509322929352 FERMT2 1 GO:0035728 response to hepatocyte growth factor 1/389 19/18722 0.329095925250292 0.631509322929352 NRP1 1 GO:0036498 IRE1-mediated unfolded protein response 1/389 19/18722 0.329095925250292 0.631509322929352 XBP1 1 GO:0043652 engulfment of apoptotic cell 1/389 19/18722 0.329095925250292 0.631509322929352 XKR8 1 GO:0045618 positive regulation of keratinocyte differentiation 1/389 19/18722 0.329095925250292 0.631509322929352 PRKCH 1 GO:0046716 muscle cell cellular homeostasis 1/389 19/18722 0.329095925250292 0.631509322929352 DMD 1 GO:0046782 regulation of viral transcription 1/389 19/18722 0.329095925250292 0.631509322929352 TRIM27 1 GO:0051444 negative regulation of ubiquitin-protein transferase activity 1/389 19/18722 0.329095925250292 0.631509322929352 ABL1 1 GO:0051571 positive regulation of histone H3-K4 methylation 1/389 19/18722 0.329095925250292 0.631509322929352 WDR5 1 GO:0060065 uterus development 1/389 19/18722 0.329095925250292 0.631509322929352 KDM5B 1 GO:0060216 definitive hemopoiesis 1/389 19/18722 0.329095925250292 0.631509322929352 RBFOX2 1 GO:0062099 negative regulation of programmed necrotic cell death 1/389 19/18722 0.329095925250292 0.631509322929352 SLC25A4 1 GO:0070734 histone H3-K27 methylation 1/389 19/18722 0.329095925250292 0.631509322929352 EZH2 1 GO:0070989 oxidative demethylation 1/389 19/18722 0.329095925250292 0.631509322929352 TDG 1 GO:0071545 inositol phosphate catabolic process 1/389 19/18722 0.329095925250292 0.631509322929352 SYNJ2 1 GO:0086014 atrial cardiac muscle cell action potential 1/389 19/18722 0.329095925250292 0.631509322929352 GJA1 1 GO:0086026 atrial cardiac muscle cell to AV node cell signaling 1/389 19/18722 0.329095925250292 0.631509322929352 GJA1 1 GO:0086066 atrial cardiac muscle cell to AV node cell communication 1/389 19/18722 0.329095925250292 0.631509322929352 GJA1 1 GO:0097501 stress response to metal ion 1/389 19/18722 0.329095925250292 0.631509322929352 MT1A 1 GO:0097623 potassium ion export across plasma membrane 1/389 19/18722 0.329095925250292 0.631509322929352 ANO6 1 GO:1903204 negative regulation of oxidative stress-induced neuron death 1/389 19/18722 0.329095925250292 0.631509322929352 SLC7A11 1 GO:1903975 regulation of glial cell migration 1/389 19/18722 0.329095925250292 0.631509322929352 LRP1 1 GO:2000042 negative regulation of double-strand break repair via homologous recombination 1/389 19/18722 0.329095925250292 0.631509322929352 MAGEF1 1 GO:2000369 regulation of clathrin-dependent endocytosis 1/389 19/18722 0.329095925250292 0.631509322929352 AAK1 1 GO:0006874 cellular calcium ion homeostasis 11/389 448/18722 0.329174451025143 0.631509322929352 SLC35G1/ATP7B/GJA1/LRP1/C19orf12/ACKR2/ABL1/CLN3/CHERP/DMD/ITGAV 11 GO:0071241 cellular response to inorganic substance 6/389 226/18722 0.32991007178513 0.632587819032791 SYT1/CDH1/MT1A/BLM/CEBPA/EGFR 6 GO:0007292 female gamete generation 4/389 140/18722 0.33204258955274 0.634856685418551 ASPM/LGR5/ADAMTS1/ZFX 4 GO:0002011 morphogenesis of an epithelial sheet 2/389 57/18722 0.332485952604725 0.634856685418551 DAG1/FERMT2 2 GO:0010883 regulation of lipid storage 2/389 57/18722 0.332485952604725 0.634856685418551 PPARG/ITGAV 2 GO:0033619 membrane protein proteolysis 2/389 57/18722 0.332485952604725 0.634856685418551 DAG1/LRIG2 2 GO:0051205 protein insertion into membrane 2/389 57/18722 0.332485952604725 0.634856685418551 EMC1/EGFR 2 GO:0060042 retina morphogenesis in camera-type eye 2/389 57/18722 0.332485952604725 0.634856685418551 LRP5/AHI1 2 GO:0061005 cell differentiation involved in kidney development 2/389 57/18722 0.332485952604725 0.634856685418551 GLI3/YAP1 2 GO:1902017 regulation of cilium assembly 2/389 57/18722 0.332485952604725 0.634856685418551 DCDC2/YAP1 2 GO:0003333 amino acid transmembrane transport 3/389 98/18722 0.333228757154402 0.635277196728753 SLC7A11/SLC1A3/SLC38A9 3 GO:0043502 regulation of muscle adaptation 3/389 98/18722 0.333228757154402 0.635277196728753 DAG1/CAMK2G/IL6ST 3 GO:1902882 regulation of response to oxidative stress 3/389 98/18722 0.333228757154402 0.635277196728753 MET/SLC7A11/AIFM2 3 GO:0090132 epithelium migration 9/389 360/18722 0.333791348853637 0.636017267120802 MET/MARVELD3/EPHB4/PPARG/NR2F2/NRP1/DOCK5/ABL1/PTK2 9 GO:0016571 histone methylation 4/389 141/18722 0.336758547590823 0.638317898922373 SUV39H1/EZH2/SETD4/WDR5 4 GO:0030183 B cell differentiation 4/389 141/18722 0.336758547590823 0.638317898922373 ABL1/MMP14/EZH2/XBP1 4 GO:0034341 response to interferon-gamma 4/389 141/18722 0.336758547590823 0.638317898922373 PPARG/CDC42EP4/RAB7B/MYO1C 4 GO:0035296 regulation of tube diameter 4/389 141/18722 0.336758547590823 0.638317898922373 GJA1/DOCK5/HMGCR/EGFR 4 GO:0097746 blood vessel diameter maintenance 4/389 141/18722 0.336758547590823 0.638317898922373 GJA1/DOCK5/HMGCR/EGFR 4 GO:0019058 viral life cycle 8/389 317/18722 0.3387309014593 0.638317898922373 DAG1/SCARB2/TFRC/NRP1/ITGB5/TRIM27/ITGAV/EGFR 8 GO:0021549 cerebellum development 3/389 99/18722 0.33892414910509 0.638317898922373 ABL1/SERPINE2/EZH2 3 GO:0110149 regulation of biomineralization 3/389 99/18722 0.33892414910509 0.638317898922373 ACVR2A/FBN2/ANO6 3 GO:0010574 regulation of vascular endothelial growth factor production 2/389 58/18722 0.340092193434081 0.638317898922373 NDRG2/IL6ST 2 GO:0035904 aorta development 2/389 58/18722 0.340092193434081 0.638317898922373 LRP2/LRP1 2 GO:2000736 regulation of stem cell differentiation 2/389 58/18722 0.340092193434081 0.638317898922373 YAP1/ABL1 2 GO:0002040 sprouting angiogenesis 5/389 185/18722 0.340189510718737 0.638317898922373 SEMA6A/EPHB4/TJP1/NRP1/ABL1 5 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 7/389 273/18722 0.340251491150427 0.638317898922373 DSC3/CLDN4/CDH1/CLDN3/PCDHGA10/FAT1/TENM3 7 GO:0035150 regulation of tube size 4/389 142/18722 0.341477187138076 0.638317898922373 GJA1/DOCK5/HMGCR/EGFR 4 GO:0050729 positive regulation of inflammatory response 4/389 142/18722 0.341477187138076 0.638317898922373 CEBPA/SETD4/IL6ST/EGFR 4 GO:0072006 nephron development 4/389 142/18722 0.341477187138076 0.638317898922373 GLI3/YAP1/LAMA5/AHI1 4 GO:0000963 mitochondrial RNA processing 1/389 20/18722 0.343049926484193 0.638317898922373 ELAC2 1 GO:0006525 arginine metabolic process 1/389 20/18722 0.343049926484193 0.638317898922373 CLN3 1 GO:0006607 NLS-bearing protein import into nucleus 1/389 20/18722 0.343049926484193 0.638317898922373 RGPD5 1 GO:0006883 cellular sodium ion homeostasis 1/389 20/18722 0.343049926484193 0.638317898922373 SLC1A3 1 GO:0006896 Golgi to vacuole transport 1/389 20/18722 0.343049926484193 0.638317898922373 CLN3 1 GO:0007097 nuclear migration 1/389 20/18722 0.343049926484193 0.638317898922373 DYNC1H1 1 GO:0010801 negative regulation of peptidyl-threonine phosphorylation 1/389 20/18722 0.343049926484193 0.638317898922373 SPRED2 1 GO:0014047 glutamate secretion 1/389 20/18722 0.343049926484193 0.638317898922373 GJA1 1 GO:0016553 base conversion or substitution editing 1/389 20/18722 0.343049926484193 0.638317898922373 RBM47 1 GO:0032930 positive regulation of superoxide anion generation 1/389 20/18722 0.343049926484193 0.638317898922373 EGFR 1 GO:0039535 regulation of RIG-I signaling pathway 1/389 20/18722 0.343049926484193 0.638317898922373 ANKRD17 1 GO:0042359 vitamin D metabolic process 1/389 20/18722 0.343049926484193 0.638317898922373 LRP2 1 GO:0043046 DNA methylation involved in gamete generation 1/389 20/18722 0.343049926484193 0.638317898922373 DNMT3A 1 GO:0043984 histone H4-K16 acetylation 1/389 20/18722 0.343049926484193 0.638317898922373 WDR5 1 GO:0045844 positive regulation of striated muscle tissue development 1/389 20/18722 0.343049926484193 0.638317898922373 HMGCR 1 GO:0046931 pore complex assembly 1/389 20/18722 0.343049926484193 0.638317898922373 ANO6 1 GO:0048636 positive regulation of muscle organ development 1/389 20/18722 0.343049926484193 0.638317898922373 HMGCR 1 GO:0048670 regulation of collateral sprouting 1/389 20/18722 0.343049926484193 0.638317898922373 LRP1 1 GO:0060044 negative regulation of cardiac muscle cell proliferation 1/389 20/18722 0.343049926484193 0.638317898922373 GJA1 1 GO:0071397 cellular response to cholesterol 1/389 20/18722 0.343049926484193 0.638317898922373 DAG1 1 GO:0071625 vocalization behavior 1/389 20/18722 0.343049926484193 0.638317898922373 GLI3 1 GO:0072567 chemokine (C-X-C motif) ligand 2 production 1/389 20/18722 0.343049926484193 0.638317898922373 LRP1 1 GO:0097150 neuronal stem cell population maintenance 1/389 20/18722 0.343049926484193 0.638317898922373 ASPM 1 GO:0097320 plasma membrane tubulation 1/389 20/18722 0.343049926484193 0.638317898922373 MICALL1 1 GO:1901679 nucleotide transmembrane transport 1/389 20/18722 0.343049926484193 0.638317898922373 SLC25A4 1 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/389 20/18722 0.343049926484193 0.638317898922373 XBP1 1 GO:1903206 negative regulation of hydrogen peroxide-induced cell death 1/389 20/18722 0.343049926484193 0.638317898922373 MET 1 GO:1990182 exosomal secretion 1/389 20/18722 0.343049926484193 0.638317898922373 HGS 1 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production 1/389 20/18722 0.343049926484193 0.638317898922373 LRP1 1 GO:2000479 regulation of cAMP-dependent protein kinase activity 1/389 20/18722 0.343049926484193 0.638317898922373 RAPGEF2 1 GO:0016197 endosomal transport 6/389 230/18722 0.344621945343257 0.640915978922415 ZFYVE9/HGS/RAB7B/MICALL1/RAB11FIP3/TRIM27 6 GO:1901214 regulation of neuron death 8/389 319/18722 0.344963724245227 0.641224618920663 SLC7A11/ELK1/LRP1/NRP1/ABL1/CLN3/SIGMAR1/ERBB3 8 GO:0031023 microtubule organizing center organization 4/389 143/18722 0.34619778165521 0.643190682474045 KIF11/CEP76/SLC16A1/CEP44 4 GO:0032768 regulation of monooxygenase activity 2/389 59/18722 0.347671393931721 0.644028481589098 ACVR2A/EGFR 2 GO:0033013 tetrapyrrole metabolic process 2/389 59/18722 0.347671393931721 0.644028481589098 COX10/MMAB 2 GO:0043407 negative regulation of MAP kinase activity 2/389 59/18722 0.347671393931721 0.644028481589098 PPARG/HMGCR 2 GO:0051568 histone H3-K4 methylation 2/389 59/18722 0.347671393931721 0.644028481589098 SETD4/WDR5 2 GO:2000351 regulation of endothelial cell apoptotic process 2/389 59/18722 0.347671393931721 0.644028481589098 ABL1/ANO6 2 GO:0090130 tissue migration 9/389 365/18722 0.348360929931329 0.644028481589098 MET/MARVELD3/EPHB4/PPARG/NR2F2/NRP1/DOCK5/ABL1/PTK2 9 GO:0010324 membrane invagination 4/389 144/18722 0.35091961391598 0.644028481589098 IGLL1/HGS/XKR8/ANO6 4 GO:0010594 regulation of endothelial cell migration 6/389 232/18722 0.352002538370758 0.644028481589098 MET/PPARG/NR2F2/NRP1/ABL1/PTK2 6 GO:0140694 non-membrane-bounded organelle assembly 9/389 367/18722 0.354215468712595 0.644028481589098 ASPM/MAP10/CENPE/CDS1/KIF11/RACGAP1/CEP76/DYNC1H1/CEP44 9 GO:1903706 regulation of hemopoiesis 9/389 367/18722 0.354215468712595 0.644028481589098 ACVR2A/GLI3/RAB7B/MEIS2/ABL1/MMP14/RBFOX2/TRIB1/XBP1 9 GO:0036293 response to decreased oxygen levels 8/389 322/18722 0.354342078377342 0.644028481589098 PLAU/PLOD1/DNMT3A/CLDN3/MMP14/SUV39H1/TM9SF4/SLC2A1 8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 2/389 60/18722 0.355221396637976 0.644028481589098 SRRM4/RBFOX2 2 GO:0006893 Golgi to plasma membrane transport 2/389 60/18722 0.355221396637976 0.644028481589098 CLN3/ARL3 2 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 2/389 60/18722 0.355221396637976 0.644028481589098 FZR1/BLM 2 GO:0051965 positive regulation of synapse assembly 2/389 60/18722 0.355221396637976 0.644028481589098 EPHB3/TPBG 2 GO:0055008 cardiac muscle tissue morphogenesis 2/389 60/18722 0.355221396637976 0.644028481589098 LRP2/FGFR2 2 GO:1903670 regulation of sprouting angiogenesis 2/389 60/18722 0.355221396637976 0.644028481589098 SEMA6A/TJP1 2 GO:0043524 negative regulation of neuron apoptotic process 4/389 145/18722 0.355641976132751 0.644028481589098 LRP1/NRP1/CLN3/ERBB3 4 GO:0046578 regulation of Ras protein signal transduction 5/389 189/18722 0.356647913148679 0.644028481589098 MET/NRP1/ABL1/ADGRG1/STK19 5 GO:0000002 mitochondrial genome maintenance 1/389 21/18722 0.356714431809701 0.644028481589098 SLC25A4 1 GO:0006244 pyrimidine nucleotide catabolic process 1/389 21/18722 0.356714431809701 0.644028481589098 TDG 1 GO:0006450 regulation of translational fidelity 1/389 21/18722 0.356714431809701 0.644028481589098 TARS2 1 GO:0006925 inflammatory cell apoptotic process 1/389 21/18722 0.356714431809701 0.644028481589098 SLC7A11 1 GO:0007289 spermatid nucleus differentiation 1/389 21/18722 0.356714431809701 0.644028481589098 PYGO1 1 GO:0009067 aspartate family amino acid biosynthetic process 1/389 21/18722 0.356714431809701 0.644028481589098 MTHFD2L 1 GO:0010766 negative regulation of sodium ion transport 1/389 21/18722 0.356714431809701 0.644028481589098 SERPINE2 1 GO:0010878 cholesterol storage 1/389 21/18722 0.356714431809701 0.644028481589098 PPARG 1 GO:0031145 anaphase-promoting complex-dependent catabolic process 1/389 21/18722 0.356714431809701 0.644028481589098 FZR1 1 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane 1/389 21/18722 0.356714431809701 0.644028481589098 SYT1 1 GO:0033630 positive regulation of cell adhesion mediated by integrin 1/389 21/18722 0.356714431809701 0.644028481589098 RAC3 1 GO:0033962 P-body assembly 1/389 21/18722 0.356714431809701 0.644028481589098 DYNC1H1 1 GO:0034035 purine ribonucleoside bisphosphate metabolic process 1/389 21/18722 0.356714431809701 0.644028481589098 SLC26A2 1 GO:0044241 lipid digestion 1/389 21/18722 0.356714431809701 0.644028481589098 LIMA1 1 GO:0046599 regulation of centriole replication 1/389 21/18722 0.356714431809701 0.644028481589098 CEP76 1 GO:0048714 positive regulation of oligodendrocyte differentiation 1/389 21/18722 0.356714431809701 0.644028481589098 DAG1 1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process 1/389 21/18722 0.356714431809701 0.644028481589098 SLC26A2 1 GO:0050849 negative regulation of calcium-mediated signaling 1/389 21/18722 0.356714431809701 0.644028481589098 FHL2 1 GO:0060972 left/right pattern formation 1/389 21/18722 0.356714431809701 0.644028481589098 AHI1 1 GO:0070584 mitochondrion morphogenesis 1/389 21/18722 0.356714431809701 0.644028481589098 WASF1 1 GO:0072170 metanephric tubule development 1/389 21/18722 0.356714431809701 0.644028481589098 YAP1 1 GO:0072243 metanephric nephron epithelium development 1/389 21/18722 0.356714431809701 0.644028481589098 YAP1 1 GO:0090026 positive regulation of monocyte chemotaxis 1/389 21/18722 0.356714431809701 0.644028481589098 ANO6 1 GO:0090141 positive regulation of mitochondrial fission 1/389 21/18722 0.356714431809701 0.644028481589098 MIEF2 1 GO:0097734 extracellular exosome biogenesis 1/389 21/18722 0.356714431809701 0.644028481589098 HGS 1 GO:0098856 intestinal lipid absorption 1/389 21/18722 0.356714431809701 0.644028481589098 LIMA1 1 GO:0099500 vesicle fusion to plasma membrane 1/389 21/18722 0.356714431809701 0.644028481589098 SYT1 1 GO:0099515 actin filament-based transport 1/389 21/18722 0.356714431809701 0.644028481589098 MYO1C 1 GO:1900118 negative regulation of execution phase of apoptosis 1/389 21/18722 0.356714431809701 0.644028481589098 FZD3 1 GO:1901863 positive regulation of muscle tissue development 1/389 21/18722 0.356714431809701 0.644028481589098 HMGCR 1 GO:1902307 positive regulation of sodium ion transmembrane transport 1/389 21/18722 0.356714431809701 0.644028481589098 DMD 1 GO:1902473 regulation of protein localization to synapse 1/389 21/18722 0.356714431809701 0.644028481589098 DAG1 1 GO:1903429 regulation of cell maturation 1/389 21/18722 0.356714431809701 0.644028481589098 RAC3 1 GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane 1/389 21/18722 0.356714431809701 0.644028481589098 ATP7B 1 GO:2000047 regulation of cell-cell adhesion mediated by cadherin 1/389 21/18722 0.356714431809701 0.644028481589098 TJP1 1 GO:2000178 negative regulation of neural precursor cell proliferation 1/389 21/18722 0.356714431809701 0.644028481589098 SPINT1 1 GO:2000291 regulation of myoblast proliferation 1/389 21/18722 0.356714431809701 0.644028481589098 MEIS2 1 GO:2001014 regulation of skeletal muscle cell differentiation 1/389 21/18722 0.356714431809701 0.644028481589098 GPC1 1 GO:0043542 endothelial cell migration 7/389 279/18722 0.360500226888524 0.650541478210019 MET/EPHB4/PPARG/NR2F2/NRP1/ABL1/PTK2 7 GO:0009566 fertilization 5/389 190/18722 0.36076838523434 0.650703412932561 UNC13B/NR2F2/UBXN8/ZFX/KDM5B 5 GO:0003279 cardiac septum development 3/389 103/18722 0.361663551251616 0.651351590822047 LRP2/NRP1/FGFR2 3 GO:0045639 positive regulation of myeloid cell differentiation 3/389 103/18722 0.361663551251616 0.651351590822047 ACVR2A/RAB7B/TRIB1 3 GO:0090277 positive regulation of peptide hormone secretion 3/389 103/18722 0.361663551251616 0.651351590822047 GJA1/LRP1/EGFR 3 GO:0019748 secondary metabolic process 2/389 61/18722 0.362740144939526 0.651647226996103 SLC7A11/RAPGEF2 2 GO:0030199 collagen fibril organization 2/389 61/18722 0.362740144939526 0.651647226996103 COL14A1/TLL1 2 GO:0090342 regulation of cell aging 2/389 61/18722 0.362740144939526 0.651647226996103 ABL1/FZR1 2 GO:0060041 retina development in camera-type eye 4/389 147/18722 0.365085507167791 0.651647226996103 COL4A1/LRP5/NRP1/AHI1 4 GO:1902652 secondary alcohol metabolic process 4/389 147/18722 0.365085507167791 0.651647226996103 LRP5/HMGCR/CEBPA/LIMA1 4 GO:1903531 negative regulation of secretion by cell 4/389 147/18722 0.365085507167791 0.651647226996103 RHBDF1/GJA1/RAB11FIP3/HMGCR 4 GO:0016072 rRNA metabolic process 6/389 236/18722 0.366798868105323 0.651647226996103 RCL1/MRM1/SUV39H1/RPF1/WDR36/NSUN4 6 GO:0048738 cardiac muscle tissue development 6/389 236/18722 0.366798868105323 0.651647226996103 LRP2/GJA1/YAP1/FGFR2/SGCB/FHL2 6 GO:0022600 digestive system process 3/389 104/18722 0.367332167288323 0.651647226996103 PBLD/TJP2/LIMA1 3 GO:0045621 positive regulation of lymphocyte differentiation 3/389 104/18722 0.367332167288323 0.651647226996103 GLI3/MMP14/XBP1 3 GO:0060419 heart growth 3/389 104/18722 0.367332167288323 0.651647226996103 GJA1/YAP1/FGFR2 3 GO:0032872 regulation of stress-activated MAPK cascade 5/389 192/18722 0.369013049637281 0.651647226996103 MARVELD3/STK25/HMGCR/STK3/EGFR 5 GO:0043484 regulation of RNA splicing 4/389 148/18722 0.369805308609978 0.651647226996103 SRRM4/RBFOX2/HNRNPLL/ESRP1 4 GO:0007398 ectoderm development 1/389 22/18722 0.370095432078458 0.651647226996103 ITGA6 1 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 1/389 22/18722 0.370095432078458 0.651647226996103 DMD 1 GO:0021854 hypothalamus development 1/389 22/18722 0.370095432078458 0.651647226996103 NRP1 1 GO:0021904 dorsal/ventral neural tube patterning 1/389 22/18722 0.370095432078458 0.651647226996103 GLI3 1 GO:0022616 DNA strand elongation 1/389 22/18722 0.370095432078458 0.651647226996103 PCNA 1 GO:0030277 maintenance of gastrointestinal epithelium 1/389 22/18722 0.370095432078458 0.651647226996103 PBLD 1 GO:0031061 negative regulation of histone methylation 1/389 22/18722 0.370095432078458 0.651647226996103 WDR5 1 GO:0032069 regulation of nuclease activity 1/389 22/18722 0.370095432078458 0.651647226996103 PCNA 1 GO:0032402 melanosome transport 1/389 22/18722 0.370095432078458 0.651647226996103 ARL6 1 GO:0035024 negative regulation of Rho protein signal transduction 1/389 22/18722 0.370095432078458 0.651647226996103 MET 1 GO:0035357 peroxisome proliferator activated receptor signaling pathway 1/389 22/18722 0.370095432078458 0.651647226996103 PPARG 1 GO:0045048 protein insertion into ER membrane 1/389 22/18722 0.370095432078458 0.651647226996103 EMC1 1 GO:0045061 thymic T cell selection 1/389 22/18722 0.370095432078458 0.651647226996103 GLI3 1 GO:0045663 positive regulation of myoblast differentiation 1/389 22/18722 0.370095432078458 0.651647226996103 XKR8 1 GO:0051151 negative regulation of smooth muscle cell differentiation 1/389 22/18722 0.370095432078458 0.651647226996103 ANKRD17 1 GO:0060563 neuroepithelial cell differentiation 1/389 22/18722 0.370095432078458 0.651647226996103 ABL1 1 GO:0060965 negative regulation of gene silencing by miRNA 1/389 22/18722 0.370095432078458 0.651647226996103 PPARG 1 GO:0061042 vascular wound healing 1/389 22/18722 0.370095432078458 0.651647226996103 XBP1 1 GO:0071404 cellular response to low-density lipoprotein particle stimulus 1/389 22/18722 0.370095432078458 0.651647226996103 PPARG 1 GO:0072574 hepatocyte proliferation 1/389 22/18722 0.370095432078458 0.651647226996103 XBP1 1 GO:0072575 epithelial cell proliferation involved in liver morphogenesis 1/389 22/18722 0.370095432078458 0.651647226996103 XBP1 1 GO:1900120 regulation of receptor binding 1/389 22/18722 0.370095432078458 0.651647226996103 NRP1 1 GO:1901032 negative regulation of response to reactive oxygen species 1/389 22/18722 0.370095432078458 0.651647226996103 MET 1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus 1/389 22/18722 0.370095432078458 0.651647226996103 XBP1 1 GO:2000773 negative regulation of cellular senescence 1/389 22/18722 0.370095432078458 0.651647226996103 ABL1 1 GO:0032623 interleukin-2 production 2/389 62/18722 0.37022567982888 0.651647226996103 ABL1/TRIM27 2 GO:0032663 regulation of interleukin-2 production 2/389 62/18722 0.37022567982888 0.651647226996103 ABL1/TRIM27 2 GO:0032731 positive regulation of interleukin-1 beta production 2/389 62/18722 0.37022567982888 0.651647226996103 FZD5/NLRP2 2 GO:0046824 positive regulation of nucleocytoplasmic transport 2/389 62/18722 0.37022567982888 0.651647226996103 CDH1/GLI3 2 GO:0048488 synaptic vesicle endocytosis 2/389 62/18722 0.37022567982888 0.651647226996103 SYNJ2/SYT1 2 GO:0048663 neuron fate commitment 2/389 62/18722 0.37022567982888 0.651647226996103 GLI3/ESRP1 2 GO:0060675 ureteric bud morphogenesis 2/389 62/18722 0.37022567982888 0.651647226996103 GLI3/LAMA5 2 GO:0140238 presynaptic endocytosis 2/389 62/18722 0.37022567982888 0.651647226996103 SYNJ2/SYT1 2 GO:1902750 negative regulation of cell cycle G2/M phase transition 2/389 62/18722 0.37022567982888 0.651647226996103 FZR1/BLM 2 GO:1903532 positive regulation of secretion by cell 7/389 282/18722 0.370665263304424 0.652106230232144 UNC13B/SYT1/GJA1/WLS/LRP1/HGS/EGFR 7 GO:2001022 positive regulation of response to DNA damage stimulus 3/389 105/18722 0.372992102954866 0.655883413440885 SPRED2/PCNA/EGFR 3 GO:0051146 striated muscle cell differentiation 7/389 283/18722 0.37405784782552 0.657440467961287 MMP14/MYOF/EZH2/SGCB/FHL2/BHLHE41/XBP1 7 GO:0032368 regulation of lipid transport 4/389 149/18722 0.374522905446462 0.657940768864763 PPARG/LRP1/KDM5B/ITGAV 4 GO:1901654 response to ketone 5/389 194/18722 0.377259574380119 0.661707388007114 ELK1/CLDN4/YAP1/PCNA/EGFR 5 GO:0015850 organic hydroxy compound transport 7/389 284/18722 0.377452111500941 0.661707388007114 SYT1/PPARG/LRP1/KDM5B/SERAC1/SLC16A1/LIMA1 7 GO:0072171 mesonephric tubule morphogenesis 2/389 63/18722 0.377676136754413 0.661707388007114 GLI3/LAMA5 2 GO:0002793 positive regulation of peptide secretion 3/389 106/18722 0.378642309989442 0.661707388007114 GJA1/LRP1/EGFR 3 GO:0046822 regulation of nucleocytoplasmic transport 3/389 106/18722 0.378642309989442 0.661707388007114 CDH1/GLI3/NUP58 3 GO:0071887 leukocyte apoptotic process 3/389 106/18722 0.378642309989442 0.661707388007114 SLC7A11/GLI3/RAPGEF2 3 GO:0018205 peptidyl-lysine modification 9/389 376/18722 0.380702869999253 0.661707388007114 METTL21C/PLOD1/SUV39H1/LIPT2/LIPT1/TRIM27/EZH2/SETD4/WDR5 9 GO:0070302 regulation of stress-activated protein kinase signaling cascade 5/389 195/18722 0.381382389336544 0.661707388007114 MARVELD3/STK25/HMGCR/STK3/EGFR 5 GO:0006929 substrate-dependent cell migration 1/389 23/18722 0.383198794480676 0.661707388007114 NRP1 1 GO:0018279 protein N-linked glycosylation via asparagine 1/389 23/18722 0.383198794480676 0.661707388007114 UGGT2 1 GO:0021895 cerebral cortex neuron differentiation 1/389 23/18722 0.383198794480676 0.661707388007114 RAC3 1 GO:0030194 positive regulation of blood coagulation 1/389 23/18722 0.383198794480676 0.661707388007114 ANO6 1 GO:0031338 regulation of vesicle fusion 1/389 23/18722 0.383198794480676 0.661707388007114 SYT1 1 GO:0032401 establishment of melanosome localization 1/389 23/18722 0.383198794480676 0.661707388007114 ARL6 1 GO:0035162 embryonic hemopoiesis 1/389 23/18722 0.383198794480676 0.661707388007114 STK3 1 GO:0035988 chondrocyte proliferation 1/389 23/18722 0.383198794480676 0.661707388007114 MMP14 1 GO:0036303 lymph vessel morphogenesis 1/389 23/18722 0.383198794480676 0.661707388007114 SVEP1 1 GO:0043931 ossification involved in bone maturation 1/389 23/18722 0.383198794480676 0.661707388007114 PLXNB1 1 GO:0045932 negative regulation of muscle contraction 1/389 23/18722 0.383198794480676 0.661707388007114 DOCK5 1 GO:0045943 positive regulation of transcription by RNA polymerase I 1/389 23/18722 0.383198794480676 0.661707388007114 IPPK 1 GO:0046618 xenobiotic export 1/389 23/18722 0.383198794480676 0.661707388007114 ATP7B 1 GO:0051131 chaperone-mediated protein complex assembly 1/389 23/18722 0.383198794480676 0.661707388007114 PSMG1 1 GO:0051590 positive regulation of neurotransmitter transport 1/389 23/18722 0.383198794480676 0.661707388007114 SYT1 1 GO:0051882 mitochondrial depolarization 1/389 23/18722 0.383198794480676 0.661707388007114 ABL1 1 GO:0051904 pigment granule transport 1/389 23/18722 0.383198794480676 0.661707388007114 ARL6 1 GO:0060396 growth hormone receptor signaling pathway 1/389 23/18722 0.383198794480676 0.661707388007114 PTK2 1 GO:0060487 lung epithelial cell differentiation 1/389 23/18722 0.383198794480676 0.661707388007114 YAP1 1 GO:0060547 negative regulation of necrotic cell death 1/389 23/18722 0.383198794480676 0.661707388007114 SLC25A4 1 GO:0071218 cellular response to misfolded protein 1/389 23/18722 0.383198794480676 0.661707388007114 UGGT2 1 GO:0071305 cellular response to vitamin D 1/389 23/18722 0.383198794480676 0.661707388007114 TRIM24 1 GO:0071514 genetic imprinting 1/389 23/18722 0.383198794480676 0.661707388007114 DNMT3A 1 GO:0072576 liver morphogenesis 1/389 23/18722 0.383198794480676 0.661707388007114 XBP1 1 GO:0140112 extracellular vesicle biogenesis 1/389 23/18722 0.383198794480676 0.661707388007114 HGS 1 GO:1900048 positive regulation of hemostasis 1/389 23/18722 0.383198794480676 0.661707388007114 ANO6 1 GO:1904666 regulation of ubiquitin protein ligase activity 1/389 23/18722 0.383198794480676 0.661707388007114 FZR1 1 GO:2000737 negative regulation of stem cell differentiation 1/389 23/18722 0.383198794480676 0.661707388007114 YAP1 1 GO:0000018 regulation of DNA recombination 3/389 107/18722 0.384281765642495 0.661838968478437 TFRC/MAGEF1/BLM 3 GO:0032526 response to retinoic acid 3/389 107/18722 0.384281765642495 0.661838968478437 GJA1/YAP1/FGFR2 3 GO:0051341 regulation of oxidoreductase activity 3/389 107/18722 0.384281765642495 0.661838968478437 ACVR2A/ABL1/EGFR 3 GO:0006749 glutathione metabolic process 2/389 64/18722 0.385089742558608 0.661838968478437 SLC7A11/GSTA4 2 GO:0017156 calcium-ion regulated exocytosis 2/389 64/18722 0.385089742558608 0.661838968478437 UNC13B/SYT1 2 GO:0030858 positive regulation of epithelial cell differentiation 2/389 64/18722 0.385089742558608 0.661838968478437 PRKCH/AHI1 2 GO:0046530 photoreceptor cell differentiation 2/389 64/18722 0.385089742558608 0.661838968478437 ARL3/AHI1 2 GO:0046579 positive regulation of Ras protein signal transduction 2/389 64/18722 0.385089742558608 0.661838968478437 ADGRG1/STK19 2 GO:0098930 axonal transport 2/389 64/18722 0.385089742558608 0.661838968478437 DST/DYNC1H1 2 GO:1900076 regulation of cellular response to insulin stimulus 2/389 64/18722 0.385089742558608 0.661838968478437 ECHDC3/MYO1C 2 GO:0022408 negative regulation of cell-cell adhesion 5/389 196/18722 0.385504304851982 0.661927589357428 CDH1/GLI3/ABL1/SERPINE2/PTK2 5 GO:0045664 regulation of neuron differentiation 5/389 196/18722 0.385504304851982 0.661927589357428 ASPM/GLI3/NREP/RAC3/ESRP1 5 GO:0051051 negative regulation of transport 11/389 470/18722 0.386919495154537 0.664044893566398 GABRE/PROM2/RHBDF1/GJA1/RAB11FIP3/HMGCR/SERPINE2/TRIM27/CYFIP1/ERBB3/ITGAV 11 GO:0016125 sterol metabolic process 4/389 152/18722 0.38865592828164 0.664361718853619 LRP5/HMGCR/CEBPA/LIMA1 4 GO:0050871 positive regulation of B cell activation 4/389 152/18722 0.38865592828164 0.664361718853619 IGLL1/TFRC/MMP14/XBP1 4 GO:0051092 positive regulation of NF-kappaB transcription factor activity 4/389 152/18722 0.38865592828164 0.664361718853619 PRKCH/RAB7B/TFRC/TRIM27 4 GO:0071248 cellular response to metal ion 5/389 197/18722 0.389624876135552 0.664361718853619 SYT1/CDH1/MT1A/CEBPA/EGFR 5 GO:0022037 metencephalon development 3/389 108/18722 0.38990947251977 0.664361718853619 ABL1/SERPINE2/EZH2 3 GO:0140053 mitochondrial gene expression 3/389 108/18722 0.38990947251977 0.664361718853619 TARS2/MTRF1L/ELAC2 3 GO:0097193 intrinsic apoptotic signaling pathway 7/389 288/18722 0.391040739558143 0.664361718853619 PDK2/STK25/ABL1/AEN/HELLS/CUL2/XBP1 7 GO:0006487 protein N-linked glycosylation 2/389 65/18722 0.392464812502222 0.664361718853619 UGGT2/PMM1 2 GO:0038034 signal transduction in absence of ligand 2/389 65/18722 0.392464812502222 0.664361718853619 ERBB3/ITGAV 2 GO:0045453 bone resorption 2/389 65/18722 0.392464812502222 0.664361718853619 TFRC/EGFR 2 GO:0051310 metaphase plate congression 2/389 65/18722 0.392464812502222 0.664361718853619 CENPE/DYNC1H1 2 GO:0070936 protein K48-linked ubiquitination 2/389 65/18722 0.392464812502222 0.664361718853619 HACE1/SKP2 2 GO:0072577 endothelial cell apoptotic process 2/389 65/18722 0.392464812502222 0.664361718853619 ABL1/ANO6 2 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 2/389 65/18722 0.392464812502222 0.664361718853619 ERBB3/ITGAV 2 GO:1905330 regulation of morphogenesis of an epithelium 2/389 65/18722 0.392464812502222 0.664361718853619 GJA1/ABL1 2 GO:0048167 regulation of synaptic plasticity 5/389 198/18722 0.39374366334513 0.664361718853619 LZTS1/ABL1/CLN3/SERPINE2/RAPGEF2 5 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/389 24/18722 0.396030265091244 0.664361718853619 RCL1 1 GO:0002726 positive regulation of T cell cytokine production 1/389 24/18722 0.396030265091244 0.664361718853619 FZD5 1 GO:0002755 MyD88-dependent toll-like receptor signaling pathway 1/389 24/18722 0.396030265091244 0.664361718853619 IRAK4 1 GO:0006817 phosphate ion transport 1/389 24/18722 0.396030265091244 0.664361718853619 SLC25A11 1 GO:0007035 vacuolar acidification 1/389 24/18722 0.396030265091244 0.664361718853619 CLN3 1 GO:0009219 pyrimidine deoxyribonucleotide metabolic process 1/389 24/18722 0.396030265091244 0.664361718853619 TDG 1 GO:0010288 response to lead ion 1/389 24/18722 0.396030265091244 0.664361718853619 DNMT3A 1 GO:0018196 peptidyl-asparagine modification 1/389 24/18722 0.396030265091244 0.664361718853619 UGGT2 1 GO:0032528 microvillus organization 1/389 24/18722 0.396030265091244 0.664361718853619 RAPGEF2 1 GO:0032928 regulation of superoxide anion generation 1/389 24/18722 0.396030265091244 0.664361718853619 EGFR 1 GO:0033032 regulation of myeloid cell apoptotic process 1/389 24/18722 0.396030265091244 0.664361718853619 SLC7A11 1 GO:0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 1/389 24/18722 0.396030265091244 0.664361718853619 ANKRD17 1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 1/389 24/18722 0.396030265091244 0.664361718853619 GPC1 1 GO:0044321 response to leptin 1/389 24/18722 0.396030265091244 0.664361718853619 LRP2 1 GO:0045649 regulation of macrophage differentiation 1/389 24/18722 0.396030265091244 0.664361718853619 TRIB1 1 GO:0048641 regulation of skeletal muscle tissue development 1/389 24/18722 0.396030265091244 0.664361718853619 HMGCR 1 GO:0050820 positive regulation of coagulation 1/389 24/18722 0.396030265091244 0.664361718853619 ANO6 1 GO:0050855 regulation of B cell receptor signaling pathway 1/389 24/18722 0.396030265091244 0.664361718853619 PRKCH 1 GO:0051043 regulation of membrane protein ectodomain proteolysis 1/389 24/18722 0.396030265091244 0.664361718853619 LRIG2 1 GO:0051647 nucleus localization 1/389 24/18722 0.396030265091244 0.664361718853619 DYNC1H1 1 GO:0051905 establishment of pigment granule localization 1/389 24/18722 0.396030265091244 0.664361718853619 ARL6 1 GO:0060149 negative regulation of posttranscriptional gene silencing 1/389 24/18722 0.396030265091244 0.664361718853619 PPARG 1 GO:0060479 lung cell differentiation 1/389 24/18722 0.396030265091244 0.664361718853619 YAP1 1 GO:0060571 morphogenesis of an epithelial fold 1/389 24/18722 0.396030265091244 0.664361718853619 FGFR2 1 GO:0060967 negative regulation of gene silencing by RNA 1/389 24/18722 0.396030265091244 0.664361718853619 PPARG 1 GO:0071294 cellular response to zinc ion 1/389 24/18722 0.396030265091244 0.664361718853619 MT1A 1 GO:0071378 cellular response to growth hormone stimulus 1/389 24/18722 0.396030265091244 0.664361718853619 PTK2 1 GO:0071577 zinc ion transmembrane transport 1/389 24/18722 0.396030265091244 0.664361718853619 SLC39A1 1 GO:0072530 purine-containing compound transmembrane transport 1/389 24/18722 0.396030265091244 0.664361718853619 SLC25A4 1 GO:1903861 positive regulation of dendrite extension 1/389 24/18722 0.396030265091244 0.664361718853619 SYT1 1 GO:2000209 regulation of anoikis 1/389 24/18722 0.396030265091244 0.664361718853619 PTK2 1 GO:2000353 positive regulation of endothelial cell apoptotic process 1/389 24/18722 0.396030265091244 0.664361718853619 ANO6 1 GO:2001026 regulation of endothelial cell chemotaxis 1/389 24/18722 0.396030265091244 0.664361718853619 MET 1 GO:0071103 DNA conformation change 7/389 290/18722 0.397838388770262 0.667088093721907 ABL1/WRNIP1/SUV39H1/BLM/SMC2/MCM5/HELLS 7 GO:0050766 positive regulation of phagocytosis 2/389 66/18722 0.399799747372126 0.669453479644694 LRP1/ANO6 2 GO:0071300 cellular response to retinoic acid 2/389 66/18722 0.399799747372126 0.669453479644694 YAP1/FGFR2 2 GO:1905953 negative regulation of lipid localization 2/389 66/18722 0.399799747372126 0.669453479644694 PPARG/ITGAV 2 GO:0003014 renal system process 3/389 110/18722 0.401125776109881 0.670633521180402 GJA1/CLDN4/CLN3 3 GO:0048259 regulation of receptor-mediated endocytosis 3/389 110/18722 0.401125776109881 0.670633521180402 AAK1/AHI1/ITGAV 3 GO:0060271 cilium assembly 8/389 337/18722 0.40156470879168 0.670633521180402 DCDC2/ARL6/YAP1/GALNT11/LAMA5/ARL3/SPAG16/AHI1 8 GO:0072522 purine-containing compound biosynthetic process 5/389 200/18722 0.401974151303698 0.670633521180402 PDK2/SLC26A2/SHMT1/MTHFD2L/COASY 5 GO:0006606 protein import into nucleus 4/389 155/18722 0.402745989209634 0.670633521180402 RGPD5/CDH1/GLI3/NUP58 4 GO:0007519 skeletal muscle tissue development 4/389 155/18722 0.402745989209634 0.670633521180402 NR2F2/HMGCR/DMD/GPC1 4 GO:0046434 organophosphate catabolic process 4/389 155/18722 0.402745989209634 0.670633521180402 SYNJ2/PLBD1/ABHD12/TDG 4 GO:0061077 chaperone-mediated protein folding 2/389 67/18722 0.407093030670653 0.670633521180402 P3H1/FKBP4 2 GO:0072665 protein localization to vacuole 2/389 67/18722 0.407093030670653 0.670633521180402 HGS/SCARB2 2 GO:0009267 cellular response to starvation 4/389 156/18722 0.407430266312255 0.670633521180402 CTSV/SIK2/SLC2A1/XBP1 4 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 1/389 25/18722 0.408595471363546 0.670633521180402 GJA1 1 GO:0003094 glomerular filtration 1/389 25/18722 0.408595471363546 0.670633521180402 GJA1 1 GO:0006658 phosphatidylserine metabolic process 1/389 25/18722 0.408595471363546 0.670633521180402 ABHD12 1 GO:0007288 sperm axoneme assembly 1/389 25/18722 0.408595471363546 0.670633521180402 SPAG16 1 GO:0010842 retina layer formation 1/389 25/18722 0.408595471363546 0.670633521180402 AHI1 1 GO:0010954 positive regulation of protein processing 1/389 25/18722 0.408595471363546 0.670633521180402 MMP14 1 GO:0016540 protein autoprocessing 1/389 25/18722 0.408595471363546 0.670633521180402 SPRTN 1 GO:0030318 melanocyte differentiation 1/389 25/18722 0.408595471363546 0.670633521180402 GLI3 1 GO:0031579 membrane raft organization 1/389 25/18722 0.408595471363546 0.670633521180402 CLN3 1 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 1/389 25/18722 0.408595471363546 0.670633521180402 TRIB1 1 GO:0032104 regulation of response to extracellular stimulus 1/389 25/18722 0.408595471363546 0.670633521180402 TRIM24 1 GO:0032107 regulation of response to nutrient levels 1/389 25/18722 0.408595471363546 0.670633521180402 TRIM24 1 GO:0032400 melanosome localization 1/389 25/18722 0.408595471363546 0.670633521180402 ARL6 1 GO:0032925 regulation of activin receptor signaling pathway 1/389 25/18722 0.408595471363546 0.670633521180402 ACVR2A 1 GO:0034389 lipid droplet organization 1/389 25/18722 0.408595471363546 0.670633521180402 CDS1 1 GO:0036315 cellular response to sterol 1/389 25/18722 0.408595471363546 0.670633521180402 DAG1 1 GO:0042730 fibrinolysis 1/389 25/18722 0.408595471363546 0.670633521180402 PLAU 1 GO:0046835 carbohydrate phosphorylation 1/389 25/18722 0.408595471363546 0.670633521180402 IPPK 1 GO:0048596 embryonic camera-type eye morphogenesis 1/389 25/18722 0.408595471363546 0.670633521180402 FZD5 1 GO:0051291 protein heterooligomerization 1/389 25/18722 0.408595471363546 0.670633521180402 SYT1 1 GO:0051450 myoblast proliferation 1/389 25/18722 0.408595471363546 0.670633521180402 MEIS2 1 GO:0051788 response to misfolded protein 1/389 25/18722 0.408595471363546 0.670633521180402 UGGT2 1 GO:0060740 prostate gland epithelium morphogenesis 1/389 25/18722 0.408595471363546 0.670633521180402 FGFR2 1 GO:0072202 cell differentiation involved in metanephros development 1/389 25/18722 0.408595471363546 0.670633521180402 YAP1 1 GO:0072207 metanephric epithelium development 1/389 25/18722 0.408595471363546 0.670633521180402 YAP1 1 GO:0086064 cell communication by electrical coupling involved in cardiac conduction 1/389 25/18722 0.408595471363546 0.670633521180402 GJA1 1 GO:0090169 regulation of spindle assembly 1/389 25/18722 0.408595471363546 0.670633521180402 DYNC1H1 1 GO:0120316 sperm flagellum assembly 1/389 25/18722 0.408595471363546 0.670633521180402 SPAG16 1 GO:1901798 positive regulation of signal transduction by p53 class mediator 1/389 25/18722 0.408595471363546 0.670633521180402 SPRED2 1 GO:1903055 positive regulation of extracellular matrix organization 1/389 25/18722 0.408595471363546 0.670633521180402 DAG1 1 GO:1903792 negative regulation of anion transport 1/389 25/18722 0.408595471363546 0.670633521180402 GABRE 1 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA 1/389 25/18722 0.408595471363546 0.670633521180402 EGFR 1 GO:1903959 regulation of anion transmembrane transport 1/389 25/18722 0.408595471363546 0.670633521180402 TCAF1 1 GO:1905563 negative regulation of vascular endothelial cell proliferation 1/389 25/18722 0.408595471363546 0.670633521180402 PPARG 1 GO:0016051 carbohydrate biosynthetic process 5/389 202/18722 0.410192351346865 0.672951644337389 PDK2/GYG1/CHST11/WDR5/CHST14 5 GO:0007030 Golgi organization 4/389 157/18722 0.412107350275714 0.673655379371666 COG1/HACE1/STK25/TRAPPC8 4 GO:1902107 positive regulation of leukocyte differentiation 4/389 157/18722 0.412107350275714 0.673655379371666 GLI3/MMP14/TRIB1/XBP1 4 GO:1903708 positive regulation of hemopoiesis 4/389 157/18722 0.412107350275714 0.673655379371666 GLI3/MMP14/TRIB1/XBP1 4 GO:1990845 adaptive thermogenesis 4/389 157/18722 0.412107350275714 0.673655379371666 GJA1/DYNC1H1/SLC25A4/PRLR 4 GO:0002821 positive regulation of adaptive immune response 3/389 112/18722 0.412283741913232 0.673655379371666 FZD5/TFRC/IL6ST 3 GO:0010633 negative regulation of epithelial cell migration 3/389 112/18722 0.412283741913232 0.673655379371666 MARVELD3/PPARG/NR2F2 3 GO:0032609 interferon-gamma production 3/389 112/18722 0.412283741913232 0.673655379371666 FZD5/ABL1/TRIM27 3 GO:0032649 regulation of interferon-gamma production 3/389 112/18722 0.412283741913232 0.673655379371666 FZD5/ABL1/TRIM27 3 GO:0043406 positive regulation of MAP kinase activity 3/389 112/18722 0.412283741913232 0.673655379371666 FZD5/EZH2/EGFR 3 GO:0007585 respiratory gaseous exchange by respiratory system 2/389 68/18722 0.414343225884327 0.676414388898899 SPAG16/CHST11 2 GO:0032922 circadian regulation of gene expression 2/389 68/18722 0.414343225884327 0.676414388898899 ID4/BHLHE41 2 GO:0031623 receptor internalization 3/389 113/18722 0.417838618792178 0.676667741002481 LRP1/TFRC/AHI1 3 GO:0044344 cellular response to fibroblast growth factor stimulus 3/389 113/18722 0.417838618792178 0.676667741002481 KDM5B/FGFR2/GPC1 3 GO:0048193 Golgi vesicle transport 7/389 296/18722 0.418220455438133 0.676667741002481 GAS1/COG1/RAB7B/TRAPPC8/CLN3/SEC24C/ARL3 7 GO:0050890 cognition 7/389 296/18722 0.418220455438133 0.676667741002481 SLC7A11/MEIS2/TPBG/CLN3/HMGCR/CYFIP1/EGFR 7 GO:0002092 positive regulation of receptor internalization 1/389 26/18722 0.42089992457206 0.676667741002481 AHI1 1 GO:0002407 dendritic cell chemotaxis 1/389 26/18722 0.42089992457206 0.676667741002481 ANO6 1 GO:0003416 endochondral bone growth 1/389 26/18722 0.42089992457206 0.676667741002481 FGFR2 1 GO:0006517 protein deglycosylation 1/389 26/18722 0.42089992457206 0.676667741002481 UGGT2 1 GO:0007214 gamma-aminobutyric acid signaling pathway 1/389 26/18722 0.42089992457206 0.676667741002481 GABRE 1 GO:0008535 respiratory chain complex IV assembly 1/389 26/18722 0.42089992457206 0.676667741002481 COX10 1 GO:0014829 vascular associated smooth muscle contraction 1/389 26/18722 0.42089992457206 0.676667741002481 DOCK5 1 GO:0016226 iron-sulfur cluster assembly 1/389 26/18722 0.42089992457206 0.676667741002481 LYRM4 1 GO:0031163 metallo-sulfur cluster assembly 1/389 26/18722 0.42089992457206 0.676667741002481 LYRM4 1 GO:0033598 mammary gland epithelial cell proliferation 1/389 26/18722 0.42089992457206 0.676667741002481 KDM5B 1 GO:0034063 stress granule assembly 1/389 26/18722 0.42089992457206 0.676667741002481 DYNC1H1 1 GO:0034114 regulation of heterotypic cell-cell adhesion 1/389 26/18722 0.42089992457206 0.676667741002481 GCNT2 1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated 1/389 26/18722 0.42089992457206 0.676667741002481 WASF1 1 GO:0043501 skeletal muscle adaptation 1/389 26/18722 0.42089992457206 0.676667741002481 CAMK2G 1 GO:0046639 negative regulation of alpha-beta T cell differentiation 1/389 26/18722 0.42089992457206 0.676667741002481 GLI3 1 GO:0047497 mitochondrion transport along microtubule 1/389 26/18722 0.42089992457206 0.676667741002481 WASF1 1 GO:0048499 synaptic vesicle membrane organization 1/389 26/18722 0.42089992457206 0.676667741002481 SYT1 1 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 1/389 26/18722 0.42089992457206 0.676667741002481 PRKCH 1 GO:0051560 mitochondrial calcium ion homeostasis 1/389 26/18722 0.42089992457206 0.676667741002481 C19orf12 1 GO:0051875 pigment granule localization 1/389 26/18722 0.42089992457206 0.676667741002481 ARL6 1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 1/389 26/18722 0.42089992457206 0.676667741002481 DMD 1 GO:0060544 regulation of necroptotic process 1/389 26/18722 0.42089992457206 0.676667741002481 SLC25A4 1 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA 1/389 26/18722 0.42089992457206 0.676667741002481 EGFR 1 GO:0070977 bone maturation 1/389 26/18722 0.42089992457206 0.676667741002481 PLXNB1 1 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway 1/389 26/18722 0.42089992457206 0.676667741002481 RAPGEF2 1 GO:0097205 renal filtration 1/389 26/18722 0.42089992457206 0.676667741002481 GJA1 1 GO:1901071 glucosamine-containing compound metabolic process 1/389 26/18722 0.42089992457206 0.676667741002481 EXTL2 1 GO:2000050 regulation of non-canonical Wnt signaling pathway 1/389 26/18722 0.42089992457206 0.676667741002481 ABL1 1 GO:2000108 positive regulation of leukocyte apoptotic process 1/389 26/18722 0.42089992457206 0.676667741002481 RAPGEF2 1 GO:0051170 import into nucleus 4/389 159/18722 0.421437639400654 0.676667741002481 RGPD5/CDH1/GLI3/NUP58 4 GO:0003143 embryonic heart tube morphogenesis 2/389 69/18722 0.421548973829897 0.676667741002481 YAP1/AHI1 2 GO:0033344 cholesterol efflux 2/389 69/18722 0.421548973829897 0.676667741002481 PPARG/LRP1 2 GO:0045665 negative regulation of neuron differentiation 2/389 69/18722 0.421548973829897 0.676667741002481 ASPM/GLI3 2 GO:0060193 positive regulation of lipase activity 2/389 69/18722 0.421548973829897 0.676667741002481 FGFR2/EGFR 2 GO:0006631 fatty acid metabolic process 9/389 390/18722 0.422134079368525 0.677010988327621 CPT1C/ECHDC3/SLC27A2/PPARG/PDK2/SLC27A6/ABHD12/ACSF2/XBP1 9 GO:1901987 regulation of cell cycle phase transition 9/389 390/18722 0.422134079368525 0.677010988327621 CENPE/ADAMTS1/DCUN1D3/FZR1/BLM/ANKRD17/EZH2/EGFR/ECD 9 GO:0019751 polyol metabolic process 3/389 114/18722 0.423376284580285 0.678108612149451 SYNJ2/IPPK/INPP4A 3 GO:1903008 organelle disassembly 3/389 114/18722 0.423376284580285 0.678108612149451 SPATA18/FZD5/SLC25A4 3 GO:1904892 regulation of receptor signaling pathway via STAT 3/389 114/18722 0.423376284580285 0.678108612149451 PPARG/HGS/PRLR 3 GO:0061448 connective tissue development 6/389 252/18722 0.426055090305491 0.681722994728956 CYTL1/LRP5/GLI3/ZNF219/CHST11/XBP1 6 GO:0060415 muscle tissue morphogenesis 2/389 70/18722 0.428708990075661 0.681722994728956 LRP2/FGFR2 2 GO:0030278 regulation of ossification 3/389 115/18722 0.428895913926995 0.681722994728956 ACVR2A/FBN2/ANO6 3 GO:0043279 response to alkaloid 3/389 115/18722 0.428895913926995 0.681722994728956 SLC1A3/DNMT3A/BLM 3 GO:0046916 cellular transition metal ion homeostasis 3/389 115/18722 0.428895913926995 0.681722994728956 ATP7B/TFRC/MT1A 3 GO:0051209 release of sequestered calcium ion into cytosol 3/389 115/18722 0.428895913926995 0.681722994728956 ABL1/CHERP/DMD 3 GO:0051650 establishment of vesicle localization 4/389 161/18722 0.430732361441066 0.681722994728956 ARL6/CLN3/DYNC1H1/MYO1C 4 GO:0000469 cleavage involved in rRNA processing 1/389 27/18722 0.432949022204787 0.681722994728956 RCL1 1 GO:0001958 endochondral ossification 1/389 27/18722 0.432949022204787 0.681722994728956 MMP14 1 GO:0006783 heme biosynthetic process 1/389 27/18722 0.432949022204787 0.681722994728956 COX10 1 GO:0007263 nitric oxide mediated signal transduction 1/389 27/18722 0.432949022204787 0.681722994728956 EGFR 1 GO:0007628 adult walking behavior 1/389 27/18722 0.432949022204787 0.681722994728956 ABHD12 1 GO:0008053 mitochondrial fusion 1/389 27/18722 0.432949022204787 0.681722994728956 TFRC 1 GO:0010758 regulation of macrophage chemotaxis 1/389 27/18722 0.432949022204787 0.681722994728956 PTK2 1 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 1/389 27/18722 0.432949022204787 0.681722994728956 DMD 1 GO:0032703 negative regulation of interleukin-2 production 1/389 27/18722 0.432949022204787 0.681722994728956 TRIM27 1 GO:0034143 regulation of toll-like receptor 4 signaling pathway 1/389 27/18722 0.432949022204787 0.681722994728956 RAB7B 1 GO:0034698 response to gonadotropin 1/389 27/18722 0.432949022204787 0.681722994728956 CTSV 1 GO:0035235 ionotropic glutamate receptor signaling pathway 1/389 27/18722 0.432949022204787 0.681722994728956 CLN3 1 GO:0035459 vesicle cargo loading 1/389 27/18722 0.432949022204787 0.681722994728956 SEC24C 1 GO:0036075 replacement ossification 1/389 27/18722 0.432949022204787 0.681722994728956 MMP14 1 GO:0039529 RIG-I signaling pathway 1/389 27/18722 0.432949022204787 0.681722994728956 ANKRD17 1 GO:0045606 positive regulation of epidermal cell differentiation 1/389 27/18722 0.432949022204787 0.681722994728956 PRKCH 1 GO:0045830 positive regulation of isotype switching 1/389 27/18722 0.432949022204787 0.681722994728956 TFRC 1 GO:0046174 polyol catabolic process 1/389 27/18722 0.432949022204787 0.681722994728956 SYNJ2 1 GO:0048520 positive regulation of behavior 1/389 27/18722 0.432949022204787 0.681722994728956 GJA1 1 GO:0048873 homeostasis of number of cells within a tissue 1/389 27/18722 0.432949022204787 0.681722994728956 RAC3 1 GO:0060333 interferon-gamma-mediated signaling pathway 1/389 27/18722 0.432949022204787 0.681722994728956 PPARG 1 GO:0060512 prostate gland morphogenesis 1/389 27/18722 0.432949022204787 0.681722994728956 FGFR2 1 GO:0061437 renal system vasculature development 1/389 27/18722 0.432949022204787 0.681722994728956 NRP1 1 GO:0061440 kidney vasculature development 1/389 27/18722 0.432949022204787 0.681722994728956 NRP1 1 GO:1902883 negative regulation of response to oxidative stress 1/389 27/18722 0.432949022204787 0.681722994728956 MET 1 GO:1902914 regulation of protein polyubiquitination 1/389 27/18722 0.432949022204787 0.681722994728956 SKP2 1 GO:1903203 regulation of oxidative stress-induced neuron death 1/389 27/18722 0.432949022204787 0.681722994728956 SLC7A11 1 GO:1903205 regulation of hydrogen peroxide-induced cell death 1/389 27/18722 0.432949022204787 0.681722994728956 MET 1 GO:1903319 positive regulation of protein maturation 1/389 27/18722 0.432949022204787 0.681722994728956 MMP14 1 GO:1903421 regulation of synaptic vesicle recycling 1/389 27/18722 0.432949022204787 0.681722994728956 CYFIP1 1 GO:1903859 regulation of dendrite extension 1/389 27/18722 0.432949022204787 0.681722994728956 SYT1 1 GO:0010639 negative regulation of organelle organization 8/389 347/18722 0.433110002409375 0.681722994728956 MET/PPARG/TJP1/TFRC/YAP1/KANK4/FKBP4/LIMA1 8 GO:0070482 response to oxygen levels 8/389 347/18722 0.433110002409375 0.681722994728956 PLAU/PLOD1/DNMT3A/CLDN3/MMP14/SUV39H1/TM9SF4/SLC2A1 8 GO:0008286 insulin receptor signaling pathway 3/389 116/18722 0.43439670515436 0.68286413090429 PDK2/SIK2/SHC1 3 GO:0030518 intracellular steroid hormone receptor signaling pathway 3/389 116/18722 0.43439670515436 0.68286413090429 YAP1/RBFOX2/SKP2 3 GO:0051283 negative regulation of sequestering of calcium ion 3/389 116/18722 0.43439670515436 0.68286413090429 ABL1/CHERP/DMD 3 GO:1901215 negative regulation of neuron death 5/389 208/18722 0.434740304228851 0.683109818837837 SLC7A11/LRP1/NRP1/CLN3/ERBB3 5 GO:0000281 mitotic cytokinesis 2/389 71/18722 0.435822062436103 0.683631424389018 RACGAP1/ARL3 2 GO:0003208 cardiac ventricle morphogenesis 2/389 71/18722 0.435822062436103 0.683631424389018 LRP2/FGFR2 2 GO:0003281 ventricular septum development 2/389 71/18722 0.435822062436103 0.683631424389018 LRP2/FGFR2 2 GO:0050795 regulation of behavior 2/389 71/18722 0.435822062436103 0.683631424389018 GJA1/AHI1 2 GO:0007611 learning or memory 6/389 255/18722 0.437107883699489 0.685353590650059 SLC7A11/MEIS2/TPBG/CLN3/HMGCR/EGFR 6 GO:0002702 positive regulation of production of molecular mediator of immune response 3/389 117/18722 0.439877880004041 0.687286499774561 FZD5/TFRC/XBP1 3 GO:0072331 signal transduction by p53 class mediator 4/389 163/18722 0.439987187231427 0.687286499774561 SPRED2/PDK2/TRIM24/AEN 4 GO:0031396 regulation of protein ubiquitination 5/389 210/18722 0.442876861082984 0.687286499774561 DCUN1D3/ABL1/FZR1/SPRTN/SKP2 5 GO:0045637 regulation of myeloid cell differentiation 5/389 210/18722 0.442876861082984 0.687286499774561 ACVR2A/RAB7B/MEIS2/RBFOX2/TRIB1 5 GO:0001736 establishment of planar polarity 2/389 72/18722 0.442887048537935 0.687286499774561 FZD3/ABL1 2 GO:0002534 cytokine production involved in inflammatory response 2/389 72/18722 0.442887048537935 0.687286499774561 EZH2/CHID1 2 GO:0005977 glycogen metabolic process 2/389 72/18722 0.442887048537935 0.687286499774561 GYG1/IL6ST 2 GO:0007164 establishment of tissue polarity 2/389 72/18722 0.442887048537935 0.687286499774561 FZD3/ABL1 2 GO:0043903 regulation of biological process involved in symbiotic interaction 2/389 72/18722 0.442887048537935 0.687286499774561 TRIM27/ITGAV 2 GO:1900015 regulation of cytokine production involved in inflammatory response 2/389 72/18722 0.442887048537935 0.687286499774561 EZH2/CHID1 2 GO:0000423 mitophagy 1/389 28/18722 0.444748050306544 0.687286499774561 SLC25A4 1 GO:0000470 maturation of LSU-rRNA 1/389 28/18722 0.444748050306544 0.687286499774561 RPF1 1 GO:0002313 mature B cell differentiation involved in immune response 1/389 28/18722 0.444748050306544 0.687286499774561 XBP1 1 GO:0002507 tolerance induction 1/389 28/18722 0.444748050306544 0.687286499774561 XKR8 1 GO:0002675 positive regulation of acute inflammatory response 1/389 28/18722 0.444748050306544 0.687286499774561 IL6ST 1 GO:0006515 protein quality control for misfolded or incompletely synthesized proteins 1/389 28/18722 0.444748050306544 0.687286499774561 UGGT2 1 GO:0006516 glycoprotein catabolic process 1/389 28/18722 0.444748050306544 0.687286499774561 GPC1 1 GO:0006829 zinc ion transport 1/389 28/18722 0.444748050306544 0.687286499774561 SLC39A1 1 GO:0006972 hyperosmotic response 1/389 28/18722 0.444748050306544 0.687286499774561 SLC2A1 1 GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway 1/389 28/18722 0.444748050306544 0.687286499774561 LRP1 1 GO:0008299 isoprenoid biosynthetic process 1/389 28/18722 0.444748050306544 0.687286499774561 HMGCR 1 GO:0010575 positive regulation of vascular endothelial growth factor production 1/389 28/18722 0.444748050306544 0.687286499774561 IL6ST 1 GO:0019098 reproductive behavior 1/389 28/18722 0.444748050306544 0.687286499774561 ZFX 1 GO:0032801 receptor catabolic process 1/389 28/18722 0.444748050306544 0.687286499774561 RNF43 1 GO:0032958 inositol phosphate biosynthetic process 1/389 28/18722 0.444748050306544 0.687286499774561 IPPK 1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 1/389 28/18722 0.444748050306544 0.687286499774561 EGFR 1 GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT 1/389 28/18722 0.444748050306544 0.687286499774561 HGS 1 GO:0060325 face morphogenesis 1/389 28/18722 0.444748050306544 0.687286499774561 CRISPLD1 1 GO:0070076 histone lysine demethylation 1/389 28/18722 0.444748050306544 0.687286499774561 KDM5B 1 GO:0071280 cellular response to copper ion 1/389 28/18722 0.444748050306544 0.687286499774561 MT1A 1 GO:0080111 DNA demethylation 1/389 28/18722 0.444748050306544 0.687286499774561 TDG 1 GO:0090659 walking behavior 1/389 28/18722 0.444748050306544 0.687286499774561 ABHD12 1 GO:1903671 negative regulation of sprouting angiogenesis 1/389 28/18722 0.444748050306544 0.687286499774561 SEMA6A 1 GO:1903672 positive regulation of sprouting angiogenesis 1/389 28/18722 0.444748050306544 0.687286499774561 TJP1 1 GO:0051282 regulation of sequestering of calcium ion 3/389 118/18722 0.445338683376955 0.687907741751696 ABL1/CHERP/DMD 3 GO:0002637 regulation of immunoglobulin production 2/389 73/18722 0.449902873455655 0.692026899828248 TFRC/XBP1 2 GO:0006073 cellular glucan metabolic process 2/389 73/18722 0.449902873455655 0.692026899828248 GYG1/IL6ST 2 GO:0032456 endocytic recycling 2/389 73/18722 0.449902873455655 0.692026899828248 MICALL1/RAB11FIP3 2 GO:0032732 positive regulation of interleukin-1 production 2/389 73/18722 0.449902873455655 0.692026899828248 FZD5/NLRP2 2 GO:0042058 regulation of epidermal growth factor receptor signaling pathway 2/389 73/18722 0.449902873455655 0.692026899828248 RHBDF1/EGFR 2 GO:0044042 glucan metabolic process 2/389 73/18722 0.449902873455655 0.692026899828248 GYG1/IL6ST 2 GO:0045739 positive regulation of DNA repair 2/389 73/18722 0.449902873455655 0.692026899828248 PCNA/EGFR 2 GO:0051298 centrosome duplication 2/389 73/18722 0.449902873455655 0.692026899828248 CEP76/CEP44 2 GO:0061035 regulation of cartilage development 2/389 73/18722 0.449902873455655 0.692026899828248 GLI3/ZNF219 2 GO:0070988 demethylation 2/389 73/18722 0.449902873455655 0.692026899828248 KDM5B/TDG 2 GO:0043523 regulation of neuron apoptotic process 5/389 212/18722 0.45098531666854 0.69339943081373 LRP1/NRP1/CLN3/SIGMAR1/ERBB3 5 GO:0043112 receptor metabolic process 4/389 166/18722 0.453785558742001 0.695699173061291 RNF43/LRP1/TFRC/AHI1 4 GO:0001505 regulation of neurotransmitter levels 5/389 213/18722 0.45502809687586 0.695699173061291 UNC13B/SYT1/SLC1A3/CLN3/ZNF219 5 GO:0010592 positive regulation of lamellipodium assembly 1/389 29/18722 0.456302185774114 0.695699173061291 CYFIP1 1 GO:0015701 bicarbonate transport 1/389 29/18722 0.456302185774114 0.695699173061291 SLC26A2 1 GO:0021522 spinal cord motor neuron differentiation 1/389 29/18722 0.456302185774114 0.695699173061291 GLI3 1 GO:0031069 hair follicle morphogenesis 1/389 29/18722 0.456302185774114 0.695699173061291 FGFR2 1 GO:0032366 intracellular sterol transport 1/389 29/18722 0.456302185774114 0.695699173061291 SERAC1 1 GO:0032367 intracellular cholesterol transport 1/389 29/18722 0.456302185774114 0.695699173061291 SERAC1 1 GO:0033028 myeloid cell apoptotic process 1/389 29/18722 0.456302185774114 0.695699173061291 SLC7A11 1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity 1/389 29/18722 0.456302185774114 0.695699173061291 EGFR 1 GO:0051654 establishment of mitochondrion localization 1/389 29/18722 0.456302185774114 0.695699173061291 WASF1 1 GO:0060969 negative regulation of gene silencing 1/389 29/18722 0.456302185774114 0.695699173061291 PPARG 1 GO:0062098 regulation of programmed necrotic cell death 1/389 29/18722 0.456302185774114 0.695699173061291 SLC25A4 1 GO:0070979 protein K11-linked ubiquitination 1/389 29/18722 0.456302185774114 0.695699173061291 FZR1 1 GO:0071549 cellular response to dexamethasone stimulus 1/389 29/18722 0.456302185774114 0.695699173061291 EGFR 1 GO:0090025 regulation of monocyte chemotaxis 1/389 29/18722 0.456302185774114 0.695699173061291 ANO6 1 GO:0090114 COPII-coated vesicle budding 1/389 29/18722 0.456302185774114 0.695699173061291 SEC24C 1 GO:0098868 bone growth 1/389 29/18722 0.456302185774114 0.695699173061291 FGFR2 1 GO:1900117 regulation of execution phase of apoptosis 1/389 29/18722 0.456302185774114 0.695699173061291 FZD3 1 GO:0006635 fatty acid beta-oxidation 2/389 74/18722 0.456868527414804 0.695699173061291 CPT1C/SLC27A2 2 GO:0010822 positive regulation of mitochondrion organization 2/389 74/18722 0.456868527414804 0.695699173061291 MIEF2/SLC25A4 2 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 2/389 74/18722 0.456868527414804 0.695699173061291 YAP1/SKP2 2 GO:1903201 regulation of oxidative stress-induced cell death 2/389 74/18722 0.456868527414804 0.695699173061291 MET/SLC7A11 2 GO:0034767 positive regulation of ion transmembrane transport 4/389 167/18722 0.458360662859742 0.697680023977246 ABL1/TCAF1/DMD/ANO6 4 GO:0044242 cellular lipid catabolic process 5/389 214/18722 0.459062771417454 0.69845720790966 CPT1C/SLC27A2/PLBD1/LRP1/ABHD12 5 GO:0042752 regulation of circadian rhythm 3/389 121/18722 0.461591655380059 0.701809617452562 PPARG/SUV39H1/EZH2 3 GO:0000070 mitotic sister chromatid segregation 4/389 168/18722 0.462922791989302 0.701809617452562 MAP10/CENPE/RACGAP1/SMC2 4 GO:2000241 regulation of reproductive process 4/389 168/18722 0.462922791989302 0.701809617452562 ASPM/GJA1/FZR1/STK3 4 GO:0006094 gluconeogenesis 2/389 75/18722 0.463783063561142 0.701809617452562 PDK2/WDR5 2 GO:0033077 T cell differentiation in thymus 2/389 75/18722 0.463783063561142 0.701809617452562 FZD5/GLI3 2 GO:0060326 cell chemotaxis 7/389 310/18722 0.4654686068084 0.701809617452562 MET/JAM3/NRP1/TPBG/ACKR2/PTK2/ANO6 7 GO:0002688 regulation of leukocyte chemotaxis 3/389 122/18722 0.466963875562993 0.701809617452562 JAM3/PTK2/ANO6 3 GO:0031214 biomineral tissue development 4/389 169/18722 0.467471482448284 0.701809617452562 ACVR2A/FBN2/FGFR2/ANO6 4 GO:0000132 establishment of mitotic spindle orientation 1/389 30/18722 0.467616498604257 0.701809617452562 GJA1 1 GO:0003299 muscle hypertrophy in response to stress 1/389 30/18722 0.467616498604257 0.701809617452562 EZH2 1 GO:0007176 regulation of epidermal growth factor-activated receptor activity 1/389 30/18722 0.467616498604257 0.701809617452562 SHC1 1 GO:0007202 activation of phospholipase C activity 1/389 30/18722 0.467616498604257 0.701809617452562 EGFR 1 GO:0009264 deoxyribonucleotide catabolic process 1/389 30/18722 0.467616498604257 0.701809617452562 TDG 1 GO:0010453 regulation of cell fate commitment 1/389 30/18722 0.467616498604257 0.701809617452562 ESRP1 1 GO:0010669 epithelial structure maintenance 1/389 30/18722 0.467616498604257 0.701809617452562 PBLD 1 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 1/389 30/18722 0.467616498604257 0.701809617452562 DMD 1 GO:0014887 cardiac muscle adaptation 1/389 30/18722 0.467616498604257 0.701809617452562 EZH2 1 GO:0014898 cardiac muscle hypertrophy in response to stress 1/389 30/18722 0.467616498604257 0.701809617452562 EZH2 1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 1/389 30/18722 0.467616498604257 0.701809617452562 CTSV 1 GO:0033137 negative regulation of peptidyl-serine phosphorylation 1/389 30/18722 0.467616498604257 0.701809617452562 DMD 1 GO:0034390 smooth muscle cell apoptotic process 1/389 30/18722 0.467616498604257 0.701809617452562 PPARG 1 GO:0034391 regulation of smooth muscle cell apoptotic process 1/389 30/18722 0.467616498604257 0.701809617452562 PPARG 1 GO:0036258 multivesicular body assembly 1/389 30/18722 0.467616498604257 0.701809617452562 HGS 1 GO:0043032 positive regulation of macrophage activation 1/389 30/18722 0.467616498604257 0.701809617452562 CEBPA 1 GO:0048147 negative regulation of fibroblast proliferation 1/389 30/18722 0.467616498604257 0.701809617452562 MED31 1 GO:0048799 animal organ maturation 1/389 30/18722 0.467616498604257 0.701809617452562 PLXNB1 1 GO:0051491 positive regulation of filopodium assembly 1/389 30/18722 0.467616498604257 0.701809617452562 NRP1 1 GO:0051968 positive regulation of synaptic transmission, glutamatergic 1/389 30/18722 0.467616498604257 0.701809617452562 EGFR 1 GO:0060218 hematopoietic stem cell differentiation 1/389 30/18722 0.467616498604257 0.701809617452562 ABL1 1 GO:0061311 cell surface receptor signaling pathway involved in heart development 1/389 30/18722 0.467616498604257 0.701809617452562 GALNT11 1 GO:0070498 interleukin-1-mediated signaling pathway 1/389 30/18722 0.467616498604257 0.701809617452562 IRAK4 1 GO:1900101 regulation of endoplasmic reticulum unfolded protein response 1/389 30/18722 0.467616498604257 0.701809617452562 XBP1 1 GO:2000637 positive regulation of gene silencing by miRNA 1/389 30/18722 0.467616498604257 0.701809617452562 EGFR 1 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 6/389 264/18722 0.470006667472845 0.704326831292865 NRP1/ABL1/ERBB3/IL6ST/EGFR/SHC1 6 GO:0021536 diencephalon development 2/389 76/18722 0.470645595793998 0.704326831292865 CDH1/NRP1 2 GO:0032543 mitochondrial translation 2/389 76/18722 0.470645595793998 0.704326831292865 TARS2/MTRF1L 2 GO:0043536 positive regulation of blood vessel endothelial cell migration 2/389 76/18722 0.470645595793998 0.704326831292865 NRP1/ABL1 2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 2/389 76/18722 0.470645595793998 0.704326831292865 PDK2/AEN 2 GO:0086001 cardiac muscle cell action potential 2/389 76/18722 0.470645595793998 0.704326831292865 GJA1/DMD 2 GO:0140029 exocytic process 2/389 76/18722 0.470645595793998 0.704326831292865 UNC13B/SYT1 2 GO:0019932 second-messenger-mediated signaling 7/389 312/18722 0.472156179397372 0.706241455206746 PDK2/ACKR2/CHERP/RAPGEF2/DMD/FHL2/EGFR 7 GO:0030168 platelet activation 3/389 123/18722 0.472312286605224 0.706241455206746 SLC7A11/SERPINE2/IL6ST 3 GO:0110148 biomineralization 4/389 171/18722 0.476526743653089 0.70842502577254 ACVR2A/FBN2/FGFR2/ANO6 4 GO:0070997 neuron death 8/389 361/18722 0.47693074417518 0.70842502577254 SLC7A11/ELK1/LRP1/NRP1/ABL1/CLN3/SIGMAR1/ERBB3 8 GO:0000380 alternative mRNA splicing, via spliceosome 2/389 77/18722 0.477455296662116 0.70842502577254 SRRM4/RBFOX2 2 GO:0048644 muscle organ morphogenesis 2/389 77/18722 0.477455296662116 0.70842502577254 LRP2/FGFR2 2 GO:0001782 B cell homeostasis 1/389 31/18722 0.478695954095534 0.70842502577254 ABL1 1 GO:0002063 chondrocyte development 1/389 31/18722 0.478695954095534 0.70842502577254 CHST11 1 GO:0006779 porphyrin-containing compound biosynthetic process 1/389 31/18722 0.478695954095534 0.70842502577254 COX10 1 GO:0007190 activation of adenylate cyclase activity 1/389 31/18722 0.478695954095534 0.70842502577254 LGR5 1 GO:0008045 motor neuron axon guidance 1/389 31/18722 0.478695954095534 0.70842502577254 NRP1 1 GO:0016577 histone demethylation 1/389 31/18722 0.478695954095534 0.70842502577254 KDM5B 1 GO:0018200 peptidyl-glutamic acid modification 1/389 31/18722 0.478695954095534 0.70842502577254 GGCX 1 GO:0030212 hyaluronan metabolic process 1/389 31/18722 0.478695954095534 0.70842502577254 ITIH5 1 GO:0033014 tetrapyrrole biosynthetic process 1/389 31/18722 0.478695954095534 0.70842502577254 COX10 1 GO:0034472 snRNA 3'-end processing 1/389 31/18722 0.478695954095534 0.70842502577254 INTS1 1 GO:0035510 DNA dealkylation 1/389 31/18722 0.478695954095534 0.70842502577254 TDG 1 GO:0036257 multivesicular body organization 1/389 31/18722 0.478695954095534 0.70842502577254 HGS 1 GO:0036475 neuron death in response to oxidative stress 1/389 31/18722 0.478695954095534 0.70842502577254 SLC7A11 1 GO:0042133 neurotransmitter metabolic process 1/389 31/18722 0.478695954095534 0.70842502577254 CLN3 1 GO:0046386 deoxyribose phosphate catabolic process 1/389 31/18722 0.478695954095534 0.70842502577254 TDG 1 GO:0051569 regulation of histone H3-K4 methylation 1/389 31/18722 0.478695954095534 0.70842502577254 WDR5 1 GO:0055022 negative regulation of cardiac muscle tissue growth 1/389 31/18722 0.478695954095534 0.70842502577254 GJA1 1 GO:0060148 positive regulation of posttranscriptional gene silencing 1/389 31/18722 0.478695954095534 0.70842502577254 EGFR 1 GO:0061117 negative regulation of heart growth 1/389 31/18722 0.478695954095534 0.70842502577254 GJA1 1 GO:0070528 protein kinase C signaling 1/389 31/18722 0.478695954095534 0.70842502577254 ADGRG1 1 GO:0071168 protein localization to chromatin 1/389 31/18722 0.478695954095534 0.70842502577254 EZH2 1 GO:0046394 carboxylic acid biosynthetic process 7/389 314/18722 0.478823056904116 0.70842502577254 SLC1A3/SLC27A2/SEPHS1/CLN3/SHMT1/MTHFD2L/XBP1 7 GO:0042770 signal transduction in response to DNA damage 4/389 172/18722 0.481032437935865 0.711405231610746 SPRED2/ABL1/FZR1/BLM 4 GO:0051053 negative regulation of DNA metabolic process 3/389 125/18722 0.482935214627492 0.712638804977089 GJA1/MAGEF1/BLM 3 GO:2000027 regulation of animal organ morphogenesis 3/389 125/18722 0.482935214627492 0.712638804977089 FZD3/ABL1/AHI1 3 GO:0097529 myeloid leukocyte migration 5/389 220/18722 0.483081482132828 0.712638804977089 JAM3/MMP14/IRAK4/PTK2/ANO6 5 GO:0002237 response to molecule of bacterial origin 8/389 363/18722 0.483132997583986 0.712638804977089 FZD5/GJA1/ABL1/FGFR2/PLSCR4/GNG12/TRIB1/XBP1 8 GO:0051098 regulation of binding 8/389 363/18722 0.483132997583986 0.712638804977089 MET/BAMBI/PPARG/LRP1/NRP1/ABL1/RAPGEF2/STK3 8 GO:0009064 glutamine family amino acid metabolic process 2/389 78/18722 0.484211395320325 0.712638804977089 SLC7A11/CLN3 2 GO:0019319 hexose biosynthetic process 2/389 78/18722 0.484211395320325 0.712638804977089 PDK2/WDR5 2 GO:0032024 positive regulation of insulin secretion 2/389 78/18722 0.484211395320325 0.712638804977089 GJA1/LRP1 2 GO:0032371 regulation of sterol transport 2/389 78/18722 0.484211395320325 0.712638804977089 PPARG/LRP1 2 GO:0032374 regulation of cholesterol transport 2/389 78/18722 0.484211395320325 0.712638804977089 PPARG/LRP1 2 GO:0035050 embryonic heart tube development 2/389 78/18722 0.484211395320325 0.712638804977089 YAP1/AHI1 2 GO:0090049 regulation of cell migration involved in sprouting angiogenesis 2/389 78/18722 0.484211395320325 0.712638804977089 NRP1/ABL1 2 GO:0016053 organic acid biosynthetic process 7/389 316/18722 0.485467612975305 0.713577989017924 SLC1A3/SLC27A2/SEPHS1/CLN3/SHMT1/MTHFD2L/XBP1 7 GO:0000910 cytokinesis 4/389 173/18722 0.485522940528641 0.713577989017924 MAP10/RACGAP1/RAB11FIP3/ARL3 4 GO:0010469 regulation of signaling receptor activity 4/389 173/18722 0.485522940528641 0.713577989017924 PLAU/PPARG/NRP1/SHC1 4 GO:0071219 cellular response to molecule of bacterial origin 5/389 221/18722 0.487049976904328 0.713577989017924 FZD5/ABL1/PLSCR4/TRIB1/XBP1 5 GO:0032874 positive regulation of stress-activated MAPK cascade 3/389 126/18722 0.488208550926411 0.713577989017924 STK25/HMGCR/STK3 3 GO:0010506 regulation of autophagy 7/389 317/18722 0.488781022590183 0.713577989017924 MET/LZTS1/FZD5/ABL1/CLN3/TRIM27/SLC25A4 7 GO:0006506 GPI anchor biosynthetic process 1/389 32/18722 0.489545415004894 0.713577989017924 PIGV 1 GO:0008156 negative regulation of DNA replication 1/389 32/18722 0.489545415004894 0.713577989017924 BLM 1 GO:0009954 proximal/distal pattern formation 1/389 32/18722 0.489545415004894 0.713577989017924 GLI3 1 GO:0010644 cell communication by electrical coupling 1/389 32/18722 0.489545415004894 0.713577989017924 GJA1 1 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter 1/389 32/18722 0.489545415004894 0.713577989017924 EZH2 1 GO:0045684 positive regulation of epidermis development 1/389 32/18722 0.489545415004894 0.713577989017924 PRKCH 1 GO:0046475 glycerophospholipid catabolic process 1/389 32/18722 0.489545415004894 0.713577989017924 ABHD12 1 GO:0046856 phosphatidylinositol dephosphorylation 1/389 32/18722 0.489545415004894 0.713577989017924 SYNJ2 1 GO:0050850 positive regulation of calcium-mediated signaling 1/389 32/18722 0.489545415004894 0.713577989017924 CHERP 1 GO:0051642 centrosome localization 1/389 32/18722 0.489545415004894 0.713577989017924 ASPM 1 GO:0060323 head morphogenesis 1/389 32/18722 0.489545415004894 0.713577989017924 CRISPLD1 1 GO:0060914 heart formation 1/389 32/18722 0.489545415004894 0.713577989017924 LRP2 1 GO:0071875 adrenergic receptor signaling pathway 1/389 32/18722 0.489545415004894 0.713577989017924 RAPGEF2 1 GO:0090022 regulation of neutrophil chemotaxis 1/389 32/18722 0.489545415004894 0.713577989017924 JAM3 1 GO:1901185 negative regulation of ERBB signaling pathway 1/389 32/18722 0.489545415004894 0.713577989017924 EGFR 1 GO:1901532 regulation of hematopoietic progenitor cell differentiation 1/389 32/18722 0.489545415004894 0.713577989017924 ABL1 1 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/389 32/18722 0.489545415004894 0.713577989017924 XBP1 1 GO:1903955 positive regulation of protein targeting to mitochondrion 1/389 32/18722 0.489545415004894 0.713577989017924 FZD5 1 GO:0045619 regulation of lymphocyte differentiation 4/389 174/18722 0.489997838371069 0.713952104090806 GLI3/ABL1/MMP14/XBP1 4 GO:0032272 negative regulation of protein polymerization 2/389 79/18722 0.490913175545452 0.714429509662516 KANK4/FKBP4 2 GO:0051279 regulation of release of sequestered calcium ion into cytosol 2/389 79/18722 0.490913175545452 0.714429509662516 ABL1/DMD 2 GO:1901184 regulation of ERBB signaling pathway 2/389 79/18722 0.490913175545452 0.714429509662516 RHBDF1/EGFR 2 GO:0006911 phagocytosis, engulfment 3/389 127/18722 0.493455716118204 0.717309748496994 IGLL1/XKR8/ANO6 3 GO:0051224 negative regulation of protein transport 3/389 127/18722 0.493455716118204 0.717309748496994 RHBDF1/RAB11FIP3/HMGCR 3 GO:0007204 positive regulation of cytosolic calcium ion concentration 7/389 319/18722 0.495389130141369 0.717309748496994 GJA1/LRP1/ACKR2/ABL1/CHERP/DMD/ITGAV 7 GO:0008202 steroid metabolic process 7/389 319/18722 0.495389130141369 0.717309748496994 LRP2/SLC27A2/LRP5/HMGCR/CEBPA/PRLR/LIMA1 7 GO:0016032 viral process 9/389 415/18722 0.495529240758824 0.717309748496994 DAG1/SCARB2/TFRC/NRP1/ITGB5/TRIM27/ITGAV/EGFR/ANO6 9 GO:0021766 hippocampus development 2/389 80/18722 0.497559973809875 0.717309748496994 GLI3/EZH2 2 GO:0051303 establishment of chromosome localization 2/389 80/18722 0.497559973809875 0.717309748496994 CENPE/DYNC1H1 2 GO:0044782 cilium organization 8/389 368/18722 0.498554567603321 0.717309748496994 DCDC2/ARL6/YAP1/GALNT11/LAMA5/ARL3/SPAG16/AHI1 8 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 3/389 128/18722 0.498676171136919 0.717309748496994 STK25/HMGCR/STK3 3 GO:0010634 positive regulation of epithelial cell migration 4/389 176/18722 0.498899217363061 0.717309748496994 MET/NRP1/DOCK5/ABL1 4 GO:0043534 blood vessel endothelial cell migration 4/389 176/18722 0.498899217363061 0.717309748496994 EPHB4/PPARG/NRP1/ABL1 4 GO:0002335 mature B cell differentiation 1/389 33/18722 0.500169643659955 0.717309748496994 XBP1 1 GO:0006482 protein demethylation 1/389 33/18722 0.500169643659955 0.717309748496994 KDM5B 1 GO:0006505 GPI anchor metabolic process 1/389 33/18722 0.500169643659955 0.717309748496994 PIGV 1 GO:0006536 glutamate metabolic process 1/389 33/18722 0.500169643659955 0.717309748496994 SLC7A11 1 GO:0006654 phosphatidic acid biosynthetic process 1/389 33/18722 0.500169643659955 0.717309748496994 AGPAT4 1 GO:0006891 intra-Golgi vesicle-mediated transport 1/389 33/18722 0.500169643659955 0.717309748496994 COG1 1 GO:0008214 protein dealkylation 1/389 33/18722 0.500169643659955 0.717309748496994 KDM5B 1 GO:0010165 response to X-ray 1/389 33/18722 0.500169643659955 0.717309748496994 BLM 1 GO:0018345 protein palmitoylation 1/389 33/18722 0.500169643659955 0.717309748496994 ZDHHC13 1 GO:0021696 cerebellar cortex morphogenesis 1/389 33/18722 0.500169643659955 0.717309748496994 SERPINE2 1 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 1/389 33/18722 0.500169643659955 0.717309748496994 HGS 1 GO:0032228 regulation of synaptic transmission, GABAergic 1/389 33/18722 0.500169643659955 0.717309748496994 CLN3 1 GO:0035025 positive regulation of Rho protein signal transduction 1/389 33/18722 0.500169643659955 0.717309748496994 ADGRG1 1 GO:0036336 dendritic cell migration 1/389 33/18722 0.500169643659955 0.717309748496994 ANO6 1 GO:0040020 regulation of meiotic nuclear division 1/389 33/18722 0.500169643659955 0.717309748496994 FZR1 1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 1/389 33/18722 0.500169643659955 0.717309748496994 PTK2 1 GO:0045648 positive regulation of erythrocyte differentiation 1/389 33/18722 0.500169643659955 0.717309748496994 ACVR2A 1 GO:0048730 epidermis morphogenesis 1/389 33/18722 0.500169643659955 0.717309748496994 FGFR2 1 GO:0050974 detection of mechanical stimulus involved in sensory perception 1/389 33/18722 0.500169643659955 0.717309748496994 SERPINE2 1 GO:0061842 microtubule organizing center localization 1/389 33/18722 0.500169643659955 0.717309748496994 ASPM 1 GO:0071295 cellular response to vitamin 1/389 33/18722 0.500169643659955 0.717309748496994 TRIM24 1 GO:0071353 cellular response to interleukin-4 1/389 33/18722 0.500169643659955 0.717309748496994 XBP1 1 GO:0120033 negative regulation of plasma membrane bounded cell projection assembly 1/389 33/18722 0.500169643659955 0.717309748496994 YAP1 1 GO:1900181 negative regulation of protein localization to nucleus 1/389 33/18722 0.500169643659955 0.717309748496994 POLR1A 1 GO:1904031 positive regulation of cyclin-dependent protein kinase activity 1/389 33/18722 0.500169643659955 0.717309748496994 EGFR 1 GO:2000036 regulation of stem cell population maintenance 1/389 33/18722 0.500169643659955 0.717309748496994 YAP1 1 GO:0051648 vesicle localization 4/389 177/18722 0.503324922011104 0.719657130613954 ARL6/CLN3/DYNC1H1/MYO1C 4 GO:0071466 cellular response to xenobiotic stimulus 4/389 177/18722 0.503324922011104 0.719657130613954 TFRC/PCNA/GSTA4/EGFR 4 GO:0098739 import across plasma membrane 4/389 177/18722 0.503324922011104 0.719657130613954 LRP2/SLC7A11/SLC1A3/SLC2A1 4 GO:0001523 retinoid metabolic process 2/389 81/18722 0.504151177411218 0.719657130613954 LRP2/LRP1 2 GO:0044773 mitotic DNA damage checkpoint signaling 2/389 81/18722 0.504151177411218 0.719657130613954 FZR1/BLM 2 GO:0051817 modulation of process of other organism involved in symbiotic interaction 2/389 81/18722 0.504151177411218 0.719657130613954 DAG1/ANO6 2 GO:0060968 regulation of gene silencing 2/389 81/18722 0.504151177411218 0.719657130613954 PPARG/EGFR 2 GO:2000106 regulation of leukocyte apoptotic process 2/389 81/18722 0.504151177411218 0.719657130613954 SLC7A11/RAPGEF2 2 GO:0001819 positive regulation of cytokine production 10/389 467/18722 0.506496306498435 0.719657130613954 FZD5/LRP1/RAB7B/ABL1/POLR3F/TRIM27/SETD4/IL6ST/XBP1/NLRP2 10 GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 3/389 130/18722 0.509034893865244 0.719657130613954 GAS1/TRAPPC8/SEC24C 3 GO:0043270 positive regulation of ion transport 6/389 275/18722 0.509463425009457 0.719657130613954 SYT1/ABL1/TCAF1/PRSS8/DMD/ANO6 6 GO:0001662 behavioral fear response 1/389 34/18722 0.510573304027886 0.719657130613954 GJA1 1 GO:0002446 neutrophil mediated immunity 1/389 34/18722 0.510573304027886 0.719657130613954 IRAK4 1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 1/389 34/18722 0.510573304027886 0.719657130613954 CTSV 1 GO:0006356 regulation of transcription by RNA polymerase I 1/389 34/18722 0.510573304027886 0.719657130613954 IPPK 1 GO:0009112 nucleobase metabolic process 1/389 34/18722 0.510573304027886 0.719657130613954 SHMT1 1 GO:0009303 rRNA transcription 1/389 34/18722 0.510573304027886 0.719657130613954 IPPK 1 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 1/389 34/18722 0.510573304027886 0.719657130613954 DMD 1 GO:0016242 negative regulation of macroautophagy 1/389 34/18722 0.510573304027886 0.719657130613954 LZTS1 1 GO:0019320 hexose catabolic process 1/389 34/18722 0.510573304027886 0.719657130613954 LRP5 1 GO:0031128 developmental induction 1/389 34/18722 0.510573304027886 0.719657130613954 FZD5 1 GO:0032743 positive regulation of interleukin-2 production 1/389 34/18722 0.510573304027886 0.719657130613954 ABL1 1 GO:0035590 purinergic nucleotide receptor signaling pathway 1/389 34/18722 0.510573304027886 0.719657130613954 ANO6 1 GO:0035909 aorta morphogenesis 1/389 34/18722 0.510573304027886 0.719657130613954 LRP1 1 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus 1/389 34/18722 0.510573304027886 0.719657130613954 ANKRD17 1 GO:0043276 anoikis 1/389 34/18722 0.510573304027886 0.719657130613954 PTK2 1 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 1/389 34/18722 0.510573304027886 0.719657130613954 SPRED2 1 GO:0044319 wound healing, spreading of cells 1/389 34/18722 0.510573304027886 0.719657130613954 FERMT2 1 GO:0048261 negative regulation of receptor-mediated endocytosis 1/389 34/18722 0.510573304027886 0.719657130613954 ITGAV 1 GO:0048536 spleen development 1/389 34/18722 0.510573304027886 0.719657130613954 ABL1 1 GO:0048854 brain morphogenesis 1/389 34/18722 0.510573304027886 0.719657130613954 FZD3 1 GO:0050931 pigment cell differentiation 1/389 34/18722 0.510573304027886 0.719657130613954 GLI3 1 GO:0055094 response to lipoprotein particle 1/389 34/18722 0.510573304027886 0.719657130613954 PPARG 1 GO:0070050 neuron cellular homeostasis 1/389 34/18722 0.510573304027886 0.719657130613954 TMEM175 1 GO:0086019 cell-cell signaling involved in cardiac conduction 1/389 34/18722 0.510573304027886 0.719657130613954 GJA1 1 GO:0090505 epiboly involved in wound healing 1/389 34/18722 0.510573304027886 0.719657130613954 FERMT2 1 GO:2000352 negative regulation of endothelial cell apoptotic process 1/389 34/18722 0.510573304027886 0.719657130613954 ABL1 1 GO:2000780 negative regulation of double-strand break repair 1/389 34/18722 0.510573304027886 0.719657130613954 MAGEF1 1 GO:0098657 import into cell 5/389 227/18722 0.510625097488543 0.719657130613954 LRP2/SLC7A11/SLC1A3/SLC27A2/SLC2A1 5 GO:0007032 endosome organization 2/389 82/18722 0.51068622265668 0.719657130613954 HGS/SCARB2 2 GO:0008543 fibroblast growth factor receptor signaling pathway 2/389 82/18722 0.51068622265668 0.719657130613954 FGFR2/GPC1 2 GO:0046364 monosaccharide biosynthetic process 2/389 82/18722 0.51068622265668 0.719657130613954 PDK2/WDR5 2 GO:0050000 chromosome localization 2/389 82/18722 0.51068622265668 0.719657130613954 CENPE/DYNC1H1 2 GO:0072527 pyrimidine-containing compound metabolic process 2/389 82/18722 0.51068622265668 0.719657130613954 SLC19A3/TDG 2 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic 2/389 82/18722 0.51068622265668 0.719657130613954 RCL1/ELAC2 2 GO:1901991 negative regulation of mitotic cell cycle phase transition 4/389 179/18722 0.512124493840457 0.721405186958728 DCUN1D3/FZR1/BLM/EZH2 4 GO:0010038 response to metal ion 8/389 373/18722 0.513840170679495 0.723172367024977 ATP7B/SYT1/CDH1/DNMT3A/MT1A/PCNA/CEBPA/EGFR 8 GO:0019827 stem cell population maintenance 3/389 131/18722 0.514172181984032 0.723172367024977 ASPM/LRP5/YAP1 3 GO:0050853 B cell receptor signaling pathway 3/389 131/18722 0.514172181984032 0.723172367024977 PRKCH/IGLL1/ABL1 3 GO:1904950 negative regulation of establishment of protein localization 3/389 131/18722 0.514172181984032 0.723172367024977 RHBDF1/RAB11FIP3/HMGCR 3 GO:0006816 calcium ion transport 9/389 422/18722 0.515685814246577 0.725021651718299 SLC35G1/GJA1/ABL1/CHERP/TRIM27/CAMK2G/DMD/ITGAV/ANO6 9 GO:0001510 RNA methylation 2/389 83/18722 0.517164593100544 0.725295658277529 MRM1/NSUN4 2 GO:0050886 endocrine process 2/389 83/18722 0.517164593100544 0.725295658277529 GJA1/RAB11FIP3 2 GO:0007281 germ cell development 6/389 278/18722 0.520041517528865 0.725295658277529 ASPM/LGR5/PYGO1/JAM3/ZFX/SPAG16 6 GO:0031349 positive regulation of defense response 6/389 278/18722 0.520041517528865 0.725295658277529 GJA1/POLR3F/CEBPA/SETD4/IL6ST/EGFR 6 GO:0002209 behavioral defense response 1/389 35/18722 0.520760963741775 0.725295658277529 GJA1 1 GO:0003351 epithelial cilium movement involved in extracellular fluid movement 1/389 35/18722 0.520760963741775 0.725295658277529 SPAG16 1 GO:0006084 acetyl-CoA metabolic process 1/389 35/18722 0.520760963741775 0.725295658277529 PDK2 1 GO:0010664 negative regulation of striated muscle cell apoptotic process 1/389 35/18722 0.520760963741775 0.725295658277529 HMGCR 1 GO:0031076 embryonic camera-type eye development 1/389 35/18722 0.520760963741775 0.725295658277529 FZD5 1 GO:0033280 response to vitamin D 1/389 35/18722 0.520760963741775 0.725295658277529 TRIM24 1 GO:0034405 response to fluid shear stress 1/389 35/18722 0.520760963741775 0.725295658277529 GJA1 1 GO:0040001 establishment of mitotic spindle localization 1/389 35/18722 0.520760963741775 0.725295658277529 GJA1 1 GO:0045454 cell redox homeostasis 1/389 35/18722 0.520760963741775 0.725295658277529 TXNRD3 1 GO:0045880 positive regulation of smoothened signaling pathway 1/389 35/18722 0.520760963741775 0.725295658277529 DCDC2 1 GO:0046471 phosphatidylglycerol metabolic process 1/389 35/18722 0.520760963741775 0.725295658277529 SERAC1 1 GO:0060236 regulation of mitotic spindle organization 1/389 35/18722 0.520760963741775 0.725295658277529 DYNC1H1 1 GO:0070536 protein K63-linked deubiquitination 1/389 35/18722 0.520760963741775 0.725295658277529 USP27X 1 GO:0090504 epiboly 1/389 35/18722 0.520760963741775 0.725295658277529 FERMT2 1 GO:0098801 regulation of renal system process 1/389 35/18722 0.520760963741775 0.725295658277529 GJA1 1 GO:1903514 release of sequestered calcium ion into cytosol by endoplasmic reticulum 1/389 35/18722 0.520760963741775 0.725295658277529 DMD 1 GO:1905207 regulation of cardiocyte differentiation 1/389 35/18722 0.520760963741775 0.725295658277529 EGFR 1 GO:1905898 positive regulation of response to endoplasmic reticulum stress 1/389 35/18722 0.520760963741775 0.725295658277529 XBP1 1 GO:0097696 receptor signaling pathway via STAT 4/389 181/18722 0.520852571710679 0.725295658277529 PPARG/HGS/PRLR/IL6ST 4 GO:0099504 synaptic vesicle cycle 4/389 181/18722 0.520852571710679 0.725295658277529 SYNJ2/UNC13B/SYT1/CYFIP1 4 GO:1905952 regulation of lipid localization 4/389 181/18722 0.520852571710679 0.725295658277529 PPARG/LRP1/KDM5B/ITGAV 4 GO:0006112 energy reserve metabolic process 2/389 84/18722 0.523585817833458 0.727712453368378 GYG1/IL6ST 2 GO:0010660 regulation of muscle cell apoptotic process 2/389 84/18722 0.523585817833458 0.727712453368378 PPARG/HMGCR 2 GO:0032370 positive regulation of lipid transport 2/389 84/18722 0.523585817833458 0.727712453368378 PPARG/LRP1 2 GO:0045445 myoblast differentiation 2/389 84/18722 0.523585817833458 0.727712453368378 HMGCR/XKR8 2 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 2/389 84/18722 0.523585817833458 0.727712453368378 DCUN1D3/EZH2 2 GO:0010595 positive regulation of endothelial cell migration 3/389 133/18722 0.524360305881485 0.727956618024277 MET/NRP1/ABL1 3 GO:0046328 regulation of JNK cascade 3/389 133/18722 0.524360305881485 0.727956618024277 MARVELD3/STK3/EGFR 3 GO:0046887 positive regulation of hormone secretion 3/389 133/18722 0.524360305881485 0.727956618024277 GJA1/LRP1/EGFR 3 GO:0060401 cytosolic calcium ion transport 4/389 182/18722 0.525188944802064 0.728764378547923 SLC35G1/ABL1/CHERP/DMD 4 GO:0001508 action potential 3/389 134/18722 0.529410275251961 0.728764378547923 GJA1/CLN3/DMD 3 GO:0002819 regulation of adaptive immune response 4/389 183/18722 0.529506436600647 0.728764378547923 FZD5/TFRC/TRIM27/IL6ST 4 GO:0001656 metanephros development 2/389 85/18722 0.529949469822099 0.728764378547923 GLI3/YAP1 2 GO:0010507 negative regulation of autophagy 2/389 85/18722 0.529949469822099 0.728764378547923 MET/LZTS1 2 GO:0044774 mitotic DNA integrity checkpoint signaling 2/389 85/18722 0.529949469822099 0.728764378547923 FZR1/BLM 2 GO:0055013 cardiac muscle cell development 2/389 85/18722 0.529949469822099 0.728764378547923 SGCB/FHL2 2 GO:0060021 roof of mouth development 2/389 85/18722 0.529949469822099 0.728764378547923 EPHB3/GLI3 2 GO:0097194 execution phase of apoptosis 2/389 85/18722 0.529949469822099 0.728764378547923 FZD3/XKR8 2 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 1/389 36/18722 0.530737096085353 0.728764378547923 CTSV 1 GO:0002691 regulation of cellular extravasation 1/389 36/18722 0.530737096085353 0.728764378547923 JAM3 1 GO:0006699 bile acid biosynthetic process 1/389 36/18722 0.530737096085353 0.728764378547923 SLC27A2 1 GO:0007031 peroxisome organization 1/389 36/18722 0.530737096085353 0.728764378547923 PEX11A 1 GO:0014046 dopamine secretion 1/389 36/18722 0.530737096085353 0.728764378547923 SYT1 1 GO:0014059 regulation of dopamine secretion 1/389 36/18722 0.530737096085353 0.728764378547923 SYT1 1 GO:0016180 snRNA processing 1/389 36/18722 0.530737096085353 0.728764378547923 INTS1 1 GO:0017004 cytochrome complex assembly 1/389 36/18722 0.530737096085353 0.728764378547923 COX10 1 GO:0030224 monocyte differentiation 1/389 36/18722 0.530737096085353 0.728764378547923 PPARG 1 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 1/389 36/18722 0.530737096085353 0.728764378547923 LRP1 1 GO:0043949 regulation of cAMP-mediated signaling 1/389 36/18722 0.530737096085353 0.728764378547923 RAPGEF2 1 GO:0044060 regulation of endocrine process 1/389 36/18722 0.530737096085353 0.728764378547923 GJA1 1 GO:0045191 regulation of isotype switching 1/389 36/18722 0.530737096085353 0.728764378547923 TFRC 1 GO:0045652 regulation of megakaryocyte differentiation 1/389 36/18722 0.530737096085353 0.728764378547923 RAB7B 1 GO:0045738 negative regulation of DNA repair 1/389 36/18722 0.530737096085353 0.728764378547923 MAGEF1 1 GO:0070670 response to interleukin-4 1/389 36/18722 0.530737096085353 0.728764378547923 XBP1 1 GO:0071402 cellular response to lipoprotein particle stimulus 1/389 36/18722 0.530737096085353 0.728764378547923 PPARG 1 GO:0090322 regulation of superoxide metabolic process 1/389 36/18722 0.530737096085353 0.728764378547923 EGFR 1 GO:1903539 protein localization to postsynaptic membrane 1/389 36/18722 0.530737096085353 0.728764378547923 DAG1 1 GO:1903749 positive regulation of establishment of protein localization to mitochondrion 1/389 36/18722 0.530737096085353 0.728764378547923 FZD5 1 GO:0055001 muscle cell development 4/389 184/18722 0.53380473074884 0.732700735054956 MYOF/DMD/SGCB/FHL2 4 GO:0009581 detection of external stimulus 3/389 135/18722 0.534430302302857 0.733283413280105 CDS1/SERPINE2/PTK2 3 GO:0034103 regulation of tissue remodeling 2/389 86/18722 0.536255164297872 0.733888935526445 TFRC/EGFR 2 GO:0045921 positive regulation of exocytosis 2/389 86/18722 0.536255164297872 0.733888935526445 SYT1/HGS 2 GO:0030099 myeloid cell differentiation 8/389 381/18722 0.537967534769034 0.733888935526445 PPARG/ACVR2A/RAB7B/MEIS2/TFRC/RBFOX2/TRIB1/CEBPA 8 GO:0043401 steroid hormone mediated signaling pathway 3/389 136/18722 0.539419998864041 0.733888935526445 YAP1/RBFOX2/SKP2 3 GO:0099024 plasma membrane invagination 3/389 136/18722 0.539419998864041 0.733888935526445 IGLL1/XKR8/ANO6 3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/389 37/18722 0.540506081936943 0.733888935526445 RCL1 1 GO:0002369 T cell cytokine production 1/389 37/18722 0.540506081936943 0.733888935526445 FZD5 1 GO:0002724 regulation of T cell cytokine production 1/389 37/18722 0.540506081936943 0.733888935526445 FZD5 1 GO:0003016 respiratory system process 1/389 37/18722 0.540506081936943 0.733888935526445 SPAG16 1 GO:0003161 cardiac conduction system development 1/389 37/18722 0.540506081936943 0.733888935526445 GJA1 1 GO:0006904 vesicle docking involved in exocytosis 1/389 37/18722 0.540506081936943 0.733888935526445 UNC13B 1 GO:0007340 acrosome reaction 1/389 37/18722 0.540506081936943 0.733888935526445 UNC13B 1 GO:0016202 regulation of striated muscle tissue development 1/389 37/18722 0.540506081936943 0.733888935526445 HMGCR 1 GO:0021532 neural tube patterning 1/389 37/18722 0.540506081936943 0.733888935526445 GLI3 1 GO:0033120 positive regulation of RNA splicing 1/389 37/18722 0.540506081936943 0.733888935526445 HNRNPLL 1 GO:0033363 secretory granule organization 1/389 37/18722 0.540506081936943 0.733888935526445 SERPINE2 1 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 1/389 37/18722 0.540506081936943 0.733888935526445 GPC1 1 GO:0045616 regulation of keratinocyte differentiation 1/389 37/18722 0.540506081936943 0.733888935526445 PRKCH 1 GO:0046473 phosphatidic acid metabolic process 1/389 37/18722 0.540506081936943 0.733888935526445 AGPAT4 1 GO:0050775 positive regulation of dendrite morphogenesis 1/389 37/18722 0.540506081936943 0.733888935526445 CDKL3 1 GO:0051294 establishment of spindle orientation 1/389 37/18722 0.540506081936943 0.733888935526445 GJA1 1 GO:0051567 histone H3-K9 methylation 1/389 37/18722 0.540506081936943 0.733888935526445 SUV39H1 1 GO:0051954 positive regulation of amine transport 1/389 37/18722 0.540506081936943 0.733888935526445 SYT1 1 GO:0060416 response to growth hormone 1/389 37/18722 0.540506081936943 0.733888935526445 PTK2 1 GO:0062237 protein localization to postsynapse 1/389 37/18722 0.540506081936943 0.733888935526445 DAG1 1 GO:0072529 pyrimidine-containing compound catabolic process 1/389 37/18722 0.540506081936943 0.733888935526445 TDG 1 GO:0090218 positive regulation of lipid kinase activity 1/389 37/18722 0.540506081936943 0.733888935526445 PTK2 1 GO:1902745 positive regulation of lamellipodium organization 1/389 37/18722 0.540506081936943 0.733888935526445 CYFIP1 1 GO:0022409 positive regulation of cell-cell adhesion 6/389 284/18722 0.540923553150987 0.733947843984656 TJP1/GLI3/TFRC/GCNT2/IL6ST/XBP1 6 GO:0007018 microtubule-based movement 8/389 382/18722 0.540951961785236 0.733947843984656 DST/CENPE/WASF1/KIF11/CLN3/ARL3/SPAG16/DYNC1H1 8 GO:0008217 regulation of blood pressure 4/389 186/18722 0.542342506842022 0.734685044962542 PPARG/LRP5/NR2F2/GJA1 4 GO:0071478 cellular response to radiation 4/389 186/18722 0.542342506842022 0.734685044962542 ELK1/YAP1/PCNA/BLM 4 GO:1902115 regulation of organelle assembly 4/389 186/18722 0.542342506842022 0.734685044962542 DCDC2/YAP1/CEP76/DYNC1H1 4 GO:0044070 regulation of anion transport 2/389 87/18722 0.542502557193344 0.734685044962542 GABRE/TCAF1 2 GO:0051262 protein tetramerization 2/389 87/18722 0.542502557193344 0.734685044962542 SHMT1/STK3 2 GO:0000086 G2/M transition of mitotic cell cycle 3/389 137/18722 0.544378994211302 0.736679106452177 FZR1/BLM/SKP2 3 GO:0007586 digestion 3/389 137/18722 0.544378994211302 0.736679106452177 PBLD/TJP2/LIMA1 3 GO:1901617 organic hydroxy compound biosynthetic process 5/389 237/18722 0.548893170141832 0.738356038267593 IPPK/SLC7A11/SLC27A2/HMGCR/RAPGEF2 5 GO:0000724 double-strand break repair via homologous recombination 3/389 138/18722 0.549306934751362 0.738356038267593 MAGEF1/BLM/MCM5 3 GO:0009582 detection of abiotic stimulus 3/389 138/18722 0.549306934751362 0.738356038267593 CDS1/SERPINE2/PTK2 3 GO:0055076 transition metal ion homeostasis 3/389 138/18722 0.549306934751362 0.738356038267593 ATP7B/TFRC/MT1A 3 GO:0001825 blastocyst formation 1/389 38/18722 0.550072211673444 0.738356038267593 YAP1 1 GO:0002478 antigen processing and presentation of exogenous peptide antigen 1/389 38/18722 0.550072211673444 0.738356038267593 CTSV 1 GO:0006858 extracellular transport 1/389 38/18722 0.550072211673444 0.738356038267593 SPAG16 1 GO:0006882 cellular zinc ion homeostasis 1/389 38/18722 0.550072211673444 0.738356038267593 MT1A 1 GO:0009595 detection of biotic stimulus 1/389 38/18722 0.550072211673444 0.738356038267593 YAP1 1 GO:0010613 positive regulation of cardiac muscle hypertrophy 1/389 38/18722 0.550072211673444 0.738356038267593 IL6ST 1 GO:0010719 negative regulation of epithelial to mesenchymal transition 1/389 38/18722 0.550072211673444 0.738356038267593 SPRED2 1 GO:0032941 secretion by tissue 1/389 38/18722 0.550072211673444 0.738356038267593 EGFR 1 GO:0035886 vascular associated smooth muscle cell differentiation 1/389 38/18722 0.550072211673444 0.738356038267593 SGCB 1 GO:0042491 inner ear auditory receptor cell differentiation 1/389 38/18722 0.550072211673444 0.738356038267593 ESRP1 1 GO:0042596 fear response 1/389 38/18722 0.550072211673444 0.738356038267593 GJA1 1 GO:0046329 negative regulation of JNK cascade 1/389 38/18722 0.550072211673444 0.738356038267593 MARVELD3 1 GO:0046676 negative regulation of insulin secretion 1/389 38/18722 0.550072211673444 0.738356038267593 HMGCR 1 GO:0048246 macrophage chemotaxis 1/389 38/18722 0.550072211673444 0.738356038267593 PTK2 1 GO:0048713 regulation of oligodendrocyte differentiation 1/389 38/18722 0.550072211673444 0.738356038267593 DAG1 1 GO:0071392 cellular response to estradiol stimulus 1/389 38/18722 0.550072211673444 0.738356038267593 EGFR 1 GO:1901031 regulation of response to reactive oxygen species 1/389 38/18722 0.550072211673444 0.738356038267593 MET 1 GO:2000279 negative regulation of DNA biosynthetic process 1/389 38/18722 0.550072211673444 0.738356038267593 GJA1 1 GO:0140014 mitotic nuclear division 6/389 287/18722 0.551216892307838 0.739620311349039 MAP10/CENPE/LRP5/KIF11/RACGAP1/SMC2 6 GO:0051259 protein complex oligomerization 5/389 238/18722 0.552641756592028 0.741259465351647 SYT1/SIGMAR1/BLM/SHMT1/STK3 5 GO:0010657 muscle cell apoptotic process 2/389 89/18722 0.554821256421899 0.743656286127662 PPARG/HMGCR 2 GO:0034660 ncRNA metabolic process 10/389 485/18722 0.554836510708355 0.743656286127662 RCL1/TARS2/MRM1/SUV39H1/HARS2/INTS1/RPF1/WDR36/ELAC2/NSUN4 10 GO:0000725 recombinational repair 3/389 140/18722 0.559068320805743 0.745987765490813 MAGEF1/BLM/MCM5 3 GO:0031333 negative regulation of protein-containing complex assembly 3/389 140/18722 0.559068320805743 0.745987765490813 JAM3/KANK4/FKBP4 3 GO:0051216 cartilage development 4/389 190/18722 0.559174783893874 0.745987765490813 CYTL1/GLI3/ZNF219/CHST11 4 GO:0001941 postsynaptic membrane organization 1/389 39/18722 0.559439687035199 0.745987765490813 SLC7A11 1 GO:0014742 positive regulation of muscle hypertrophy 1/389 39/18722 0.559439687035199 0.745987765490813 IL6ST 1 GO:0017158 regulation of calcium ion-dependent exocytosis 1/389 39/18722 0.559439687035199 0.745987765490813 SYT1 1 GO:0032506 cytokinetic process 1/389 39/18722 0.559439687035199 0.745987765490813 RACGAP1 1 GO:0032728 positive regulation of interferon-beta production 1/389 39/18722 0.559439687035199 0.745987765490813 POLR3F 1 GO:0045923 positive regulation of fatty acid metabolic process 1/389 39/18722 0.559439687035199 0.745987765490813 PPARG 1 GO:0046461 neutral lipid catabolic process 1/389 39/18722 0.559439687035199 0.745987765490813 ABHD12 1 GO:0046464 acylglycerol catabolic process 1/389 39/18722 0.559439687035199 0.745987765490813 ABHD12 1 GO:0090207 regulation of triglyceride metabolic process 1/389 39/18722 0.559439687035199 0.745987765490813 MBOAT7 1 GO:0090224 regulation of spindle organization 1/389 39/18722 0.559439687035199 0.745987765490813 DYNC1H1 1 GO:1901861 regulation of muscle tissue development 1/389 39/18722 0.559439687035199 0.745987765490813 HMGCR 1 GO:0048545 response to steroid hormone 7/389 339/18722 0.559794961413526 0.746188678463132 CTSV/CLDN4/YAP1/RBFOX2/PCNA/EGFR/SKP2 7 GO:0045638 negative regulation of myeloid cell differentiation 2/389 90/18722 0.560892064696575 0.7468321869107 MEIS2/TRIB1 2 GO:0061097 regulation of protein tyrosine kinase activity 2/389 90/18722 0.560892064696575 0.7468321869107 ERBB3/SHC1 2 GO:0097581 lamellipodium organization 2/389 90/18722 0.560892064696575 0.7468321869107 WASF1/CYFIP1 2 GO:0006164 purine nucleotide biosynthetic process 4/389 191/18722 0.563330602724923 0.749805367933501 PDK2/SLC26A2/MTHFD2L/COASY 4 GO:0016241 regulation of macroautophagy 3/389 141/18722 0.563901141962589 0.750110289430461 LZTS1/CLN3/SLC25A4 3 GO:0051656 establishment of organelle localization 8/389 390/18722 0.564548623763734 0.750110289430461 CENPE/ARL6/GJA1/WASF1/STK25/CLN3/DYNC1H1/MYO1C 8 GO:0042147 retrograde transport, endosome to Golgi 2/389 91/18722 0.566903572461054 0.750110289430461 RAB7B/TRIM27 2 GO:0045582 positive regulation of T cell differentiation 2/389 91/18722 0.566903572461054 0.750110289430461 GLI3/XBP1 2 GO:0055006 cardiac cell development 2/389 91/18722 0.566903572461054 0.750110289430461 SGCB/FHL2 2 GO:1903320 regulation of protein modification by small protein conjugation or removal 5/389 242/18722 0.567482750879956 0.750110289430461 DCUN1D3/ABL1/FZR1/SPRTN/SKP2 5 GO:0002714 positive regulation of B cell mediated immunity 1/389 40/18722 0.56861262295252 0.750110289430461 TFRC 1 GO:0002891 positive regulation of immunoglobulin mediated immune response 1/389 40/18722 0.56861262295252 0.750110289430461 TFRC 1 GO:0009394 2'-deoxyribonucleotide metabolic process 1/389 40/18722 0.56861262295252 0.750110289430461 TDG 1 GO:0010863 positive regulation of phospholipase C activity 1/389 40/18722 0.56861262295252 0.750110289430461 EGFR 1 GO:0031111 negative regulation of microtubule polymerization or depolymerization 1/389 40/18722 0.56861262295252 0.750110289430461 FKBP4 1 GO:0032094 response to food 1/389 40/18722 0.56861262295252 0.750110289430461 SLC16A1 1 GO:0034122 negative regulation of toll-like receptor signaling pathway 1/389 40/18722 0.56861262295252 0.750110289430461 RAB7B 1 GO:0042073 intraciliary transport 1/389 40/18722 0.56861262295252 0.750110289430461 ARL3 1 GO:0043001 Golgi to plasma membrane protein transport 1/389 40/18722 0.56861262295252 0.750110289430461 CLN3 1 GO:0045777 positive regulation of blood pressure 1/389 40/18722 0.56861262295252 0.750110289430461 NR2F2 1 GO:0046365 monosaccharide catabolic process 1/389 40/18722 0.56861262295252 0.750110289430461 LRP5 1 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 1/389 40/18722 0.56861262295252 0.750110289430461 ABL1 1 GO:0055069 zinc ion homeostasis 1/389 40/18722 0.56861262295252 0.750110289430461 MT1A 1 GO:0055081 anion homeostasis 1/389 40/18722 0.56861262295252 0.750110289430461 SLC7A11 1 GO:0060412 ventricular septum morphogenesis 1/389 40/18722 0.56861262295252 0.750110289430461 FGFR2 1 GO:0070266 necroptotic process 1/389 40/18722 0.56861262295252 0.750110289430461 SLC25A4 1 GO:0097352 autophagosome maturation 1/389 40/18722 0.56861262295252 0.750110289430461 CLN3 1 GO:1901998 toxin transport 1/389 40/18722 0.56861262295252 0.750110289430461 NRP1 1 GO:0097553 calcium ion transmembrane import into cytosol 3/389 142/18722 0.56870165897319 0.750110289430461 ABL1/CHERP/DMD 3 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 4/389 193/18722 0.57157779566011 0.75363131625901 NRP1/ABL1/ERBB3/IL6ST 4 GO:0032496 response to lipopolysaccharide 7/389 343/18722 0.572242845588736 0.754235510611536 GJA1/ABL1/FGFR2/PLSCR4/GNG12/TRIB1/XBP1 7 GO:0006497 protein lipidation 2/389 92/18722 0.572855617282778 0.754770388811521 ZDHHC13/PIGV 2 GO:0009167 purine ribonucleoside monophosphate metabolic process 1/389 41/18722 0.577595049334678 0.758424077461885 TJP2 1 GO:0010907 positive regulation of glucose metabolic process 1/389 41/18722 0.577595049334678 0.758424077461885 WDR5 1 GO:0031062 positive regulation of histone methylation 1/389 41/18722 0.577595049334678 0.758424077461885 WDR5 1 GO:0048634 regulation of muscle organ development 1/389 41/18722 0.577595049334678 0.758424077461885 HMGCR 1 GO:0070296 sarcoplasmic reticulum calcium ion transport 1/389 41/18722 0.577595049334678 0.758424077461885 DMD 1 GO:1900371 regulation of purine nucleotide biosynthetic process 1/389 41/18722 0.577595049334678 0.758424077461885 PDK2 1 GO:1901385 regulation of voltage-gated calcium channel activity 1/389 41/18722 0.577595049334678 0.758424077461885 DMD 1 GO:1902116 negative regulation of organelle assembly 1/389 41/18722 0.577595049334678 0.758424077461885 YAP1 1 GO:1902622 regulation of neutrophil migration 1/389 41/18722 0.577595049334678 0.758424077461885 JAM3 1 GO:0033135 regulation of peptidyl-serine phosphorylation 3/389 144/18722 0.578204705271335 0.758424077461885 TFRC/DMD/EGFR 3 GO:0106106 cold-induced thermogenesis 3/389 144/18722 0.578204705271335 0.758424077461885 GJA1/DYNC1H1/PRLR 3 GO:0120161 regulation of cold-induced thermogenesis 3/389 144/18722 0.578204705271335 0.758424077461885 GJA1/DYNC1H1/PRLR 3 GO:0019217 regulation of fatty acid metabolic process 2/389 93/18722 0.578748068981745 0.758424077461885 PPARG/PDK2 2 GO:1901796 regulation of signal transduction by p53 class mediator 2/389 93/18722 0.578748068981745 0.758424077461885 SPRED2/TRIM24 2 GO:1902807 negative regulation of cell cycle G1/S phase transition 2/389 93/18722 0.578748068981745 0.758424077461885 DCUN1D3/EZH2 2 GO:0034470 ncRNA processing 8/389 395/18722 0.579026493294468 0.758516386869585 RCL1/MRM1/SUV39H1/INTS1/RPF1/WDR36/ELAC2/NSUN4 8 GO:0051402 neuron apoptotic process 5/389 246/18722 0.582068913019651 0.761954531867432 LRP1/NRP1/CLN3/SIGMAR1/ERBB3 5 GO:0071216 cellular response to biotic stimulus 5/389 246/18722 0.582068913019651 0.761954531867432 FZD5/ABL1/PLSCR4/TRIB1/XBP1 5 GO:0002690 positive regulation of leukocyte chemotaxis 2/389 94/18722 0.584580828366953 0.762956710332591 PTK2/ANO6 2 GO:0010389 regulation of G2/M transition of mitotic cell cycle 2/389 94/18722 0.584580828366953 0.762956710332591 FZR1/BLM 2 GO:0006040 amino sugar metabolic process 1/389 42/18722 0.586390912822115 0.762956710332591 EXTL2 1 GO:0007520 myoblast fusion 1/389 42/18722 0.586390912822115 0.762956710332591 MYOF 1 GO:0010591 regulation of lamellipodium assembly 1/389 42/18722 0.586390912822115 0.762956710332591 CYFIP1 1 GO:0010939 regulation of necrotic cell death 1/389 42/18722 0.586390912822115 0.762956710332591 SLC25A4 1 GO:0019692 deoxyribose phosphate metabolic process 1/389 42/18722 0.586390912822115 0.762956710332591 TDG 1 GO:0030808 regulation of nucleotide biosynthetic process 1/389 42/18722 0.586390912822115 0.762956710332591 PDK2 1 GO:0030890 positive regulation of B cell proliferation 1/389 42/18722 0.586390912822115 0.762956710332591 TFRC 1 GO:0033574 response to testosterone 1/389 42/18722 0.586390912822115 0.762956710332591 ELK1 1 GO:0042168 heme metabolic process 1/389 42/18722 0.586390912822115 0.762956710332591 COX10 1 GO:0043507 positive regulation of JUN kinase activity 1/389 42/18722 0.586390912822115 0.762956710332591 FZD5 1 GO:0045292 mRNA cis splicing, via spliceosome 1/389 42/18722 0.586390912822115 0.762956710332591 WBP4 1 GO:0046596 regulation of viral entry into host cell 1/389 42/18722 0.586390912822115 0.762956710332591 TRIM27 1 GO:0051452 intracellular pH reduction 1/389 42/18722 0.586390912822115 0.762956710332591 CLN3 1 GO:0072595 maintenance of protein localization in organelle 1/389 42/18722 0.586390912822115 0.762956710332591 GJA1 1 GO:1904037 positive regulation of epithelial cell apoptotic process 1/389 42/18722 0.586390912822115 0.762956710332591 ANO6 1 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 3/389 146/18722 0.587575459893474 0.763438769117924 LGR5/RAPGEF2/ADGRG1 3 GO:0010675 regulation of cellular carbohydrate metabolic process 3/389 146/18722 0.587575459893474 0.763438769117924 PDK2/SCARB2/WDR5 3 GO:0045580 regulation of T cell differentiation 3/389 146/18722 0.587575459893474 0.763438769117924 GLI3/ABL1/XBP1 3 GO:0010952 positive regulation of peptidase activity 4/389 197/18722 0.587808078882131 0.763438769117924 PPARG/CLDN4/CLDN3/NLRP2 4 GO:0042594 response to starvation 4/389 197/18722 0.587808078882131 0.763438769117924 CTSV/SIK2/SLC2A1/XBP1 4 GO:0002532 production of molecular mediator involved in inflammatory response 2/389 95/18722 0.5903538260112 0.765382297711642 EZH2/CHID1 2 GO:0032479 regulation of type I interferon production 2/389 95/18722 0.5903538260112 0.765382297711642 POLR3F/DTX4 2 GO:0032606 type I interferon production 2/389 95/18722 0.5903538260112 0.765382297711642 POLR3F/DTX4 2 GO:0048709 oligodendrocyte differentiation 2/389 95/18722 0.5903538260112 0.765382297711642 DAG1/GLI3 2 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 2/389 95/18722 0.5903538260112 0.765382297711642 DCUN1D3/ABL1 2 GO:0042254 ribosome biogenesis 6/389 299/18722 0.591295489819267 0.765590551569689 RCL1/MRM1/SUV39H1/RPF1/WDR36/NSUN4 6 GO:0050864 regulation of B cell activation 4/389 198/18722 0.591809407037533 0.765590551569689 IGLL1/TFRC/MMP14/XBP1 4 GO:0001504 neurotransmitter uptake 1/389 43/18722 0.595004078502639 0.765590551569689 SLC1A3 1 GO:0009268 response to pH 1/389 43/18722 0.595004078502639 0.765590551569689 GJA1 1 GO:0016266 O-glycan processing 1/389 43/18722 0.595004078502639 0.765590551569689 GALNT11 1 GO:0021983 pituitary gland development 1/389 43/18722 0.595004078502639 0.765590551569689 CDH1 1 GO:0032365 intracellular lipid transport 1/389 43/18722 0.595004078502639 0.765590551569689 SERAC1 1 GO:0034142 toll-like receptor 4 signaling pathway 1/389 43/18722 0.595004078502639 0.765590551569689 RAB7B 1 GO:0034661 ncRNA catabolic process 1/389 43/18722 0.595004078502639 0.765590551569689 ELAC2 1 GO:0042181 ketone biosynthetic process 1/389 43/18722 0.595004078502639 0.765590551569689 COQ9 1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/389 43/18722 0.595004078502639 0.765590551569689 AEN 1 GO:0045494 photoreceptor cell maintenance 1/389 43/18722 0.595004078502639 0.765590551569689 SLC2A1 1 GO:0045840 positive regulation of mitotic nuclear division 1/389 43/18722 0.595004078502639 0.765590551569689 LRP5 1 GO:0046636 negative regulation of alpha-beta T cell activation 1/389 43/18722 0.595004078502639 0.765590551569689 GLI3 1 GO:0090278 negative regulation of peptide hormone secretion 1/389 43/18722 0.595004078502639 0.765590551569689 HMGCR 1 GO:0140353 lipid export from cell 1/389 43/18722 0.595004078502639 0.765590551569689 KDM5B 1 GO:1901381 positive regulation of potassium ion transmembrane transport 1/389 43/18722 0.595004078502639 0.765590551569689 ANO6 1 GO:1903793 positive regulation of anion transport 1/389 43/18722 0.595004078502639 0.765590551569689 TCAF1 1 GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation 1/389 43/18722 0.595004078502639 0.765590551569689 PPARG 1 GO:0003073 regulation of systemic arterial blood pressure 2/389 96/18722 0.596067021063196 0.765590551569689 NR2F2/GJA1 2 GO:0006637 acyl-CoA metabolic process 2/389 96/18722 0.596067021063196 0.765590551569689 PDK2/ACSF2 2 GO:0035383 thioester metabolic process 2/389 96/18722 0.596067021063196 0.765590551569689 PDK2/ACSF2 2 GO:0042158 lipoprotein biosynthetic process 2/389 96/18722 0.596067021063196 0.765590551569689 ZDHHC13/PIGV 2 GO:0042472 inner ear morphogenesis 2/389 96/18722 0.596067021063196 0.765590551569689 FZD3/FGFR2 2 GO:0044264 cellular polysaccharide metabolic process 2/389 96/18722 0.596067021063196 0.765590551569689 GYG1/IL6ST 2 GO:1901655 cellular response to ketone 2/389 96/18722 0.596067021063196 0.765590551569689 ELK1/EGFR 2 GO:0045861 negative regulation of proteolysis 7/389 351/18722 0.596632780085417 0.765590551569689 GAS1/LRP1/LRIG2/CLN3/SERPINE2/ITIH5/SPINT1 7 GO:0044839 cell cycle G2/M phase transition 3/389 148/18722 0.596812157420517 0.765590551569689 FZR1/BLM/SKP2 3 GO:0051384 response to glucocorticoid 3/389 148/18722 0.596812157420517 0.765590551569689 CTSV/PCNA/EGFR 3 GO:0097530 granulocyte migration 3/389 148/18722 0.596812157420517 0.765590551569689 JAM3/IRAK4/PTK2 3 GO:0099003 vesicle-mediated transport in synapse 4/389 200/18722 0.599743233300761 0.768155501151954 SYNJ2/UNC13B/SYT1/CYFIP1 4 GO:0010596 negative regulation of endothelial cell migration 2/389 97/18722 0.60172040009597 0.768155501151954 PPARG/NR2F2 2 GO:0043255 regulation of carbohydrate biosynthetic process 2/389 97/18722 0.60172040009597 0.768155501151954 PDK2/WDR5 2 GO:1901216 positive regulation of neuron death 2/389 97/18722 0.60172040009597 0.768155501151954 ELK1/ABL1 2 GO:0006066 alcohol metabolic process 7/389 353/18722 0.602619253218801 0.768155501151954 SYNJ2/IPPK/LRP5/HMGCR/INPP4A/CEBPA/LIMA1 7 GO:0002792 negative regulation of peptide secretion 1/389 44/18722 0.603438331592338 0.768155501151954 HMGCR 1 GO:0005978 glycogen biosynthetic process 1/389 44/18722 0.603438331592338 0.768155501151954 GYG1 1 GO:0006775 fat-soluble vitamin metabolic process 1/389 44/18722 0.603438331592338 0.768155501151954 LRP2 1 GO:0009126 purine nucleoside monophosphate metabolic process 1/389 44/18722 0.603438331592338 0.768155501151954 TJP2 1 GO:0009250 glucan biosynthetic process 1/389 44/18722 0.603438331592338 0.768155501151954 GYG1 1 GO:0009262 deoxyribonucleotide metabolic process 1/389 44/18722 0.603438331592338 0.768155501151954 TDG 1 GO:0021517 ventral spinal cord development 1/389 44/18722 0.603438331592338 0.768155501151954 GLI3 1 GO:0021762 substantia nigra development 1/389 44/18722 0.603438331592338 0.768155501151954 NDRG2 1 GO:0042554 superoxide anion generation 1/389 44/18722 0.603438331592338 0.768155501151954 EGFR 1 GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT 1/389 44/18722 0.603438331592338 0.768155501151954 PRLR 1 GO:0048066 developmental pigmentation 1/389 44/18722 0.603438331592338 0.768155501151954 GLI3 1 GO:0048806 genitalia development 1/389 44/18722 0.603438331592338 0.768155501151954 LRP2 1 GO:0060324 face development 1/389 44/18722 0.603438331592338 0.768155501151954 CRISPLD1 1 GO:0062208 positive regulation of pattern recognition receptor signaling pathway 1/389 44/18722 0.603438331592338 0.768155501151954 ANKRD17 1 GO:1903214 regulation of protein targeting to mitochondrion 1/389 44/18722 0.603438331592338 0.768155501151954 FZD5 1 GO:1903573 negative regulation of response to endoplasmic reticulum stress 1/389 44/18722 0.603438331592338 0.768155501151954 XBP1 1 GO:0090257 regulation of muscle system process 5/389 252/18722 0.603445437565217 0.768155501151954 DAG1/DOCK5/CAMK2G/DMD/IL6ST 5 GO:0070665 positive regulation of leukocyte proliferation 3/389 150/18722 0.605913257159832 0.771027790949723 TFRC/PTK2/IL6ST 3 GO:0043473 pigmentation 2/389 98/18722 0.607313975990586 0.772076416661537 ARL6/GLI3 2 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 2/389 98/18722 0.607313975990586 0.772076416661537 HELLS/XBP1 2 GO:0000819 sister chromatid segregation 4/389 202/18722 0.607584128274914 0.772076416661537 MAP10/CENPE/RACGAP1/SMC2 4 GO:0009913 epidermal cell differentiation 4/389 202/18722 0.607584128274914 0.772076416661537 PRKCH/YAP1/ESRP1/EZH2 4 GO:0010959 regulation of metal ion transport 8/389 406/18722 0.610069374771705 0.772726131455419 GJA1/ABL1/SERPINE2/TRIM27/PRSS8/CAMK2G/DMD/ANO6 8 GO:0043535 regulation of blood vessel endothelial cell migration 3/389 151/18722 0.610412535495891 0.772726131455419 PPARG/NRP1/ABL1 3 GO:1904064 positive regulation of cation transmembrane transport 3/389 151/18722 0.610412535495891 0.772726131455419 ABL1/DMD/ANO6 3 GO:0006310 DNA recombination 6/389 305/18722 0.610620726832482 0.772726131455419 TFRC/NFRKB/MAGEF1/TSN/BLM/MCM5 6 GO:2001233 regulation of apoptotic signaling pathway 7/389 356/18722 0.611512122163456 0.772726131455419 ITGA6/YAP1/NRP1/STK3/ITGAV/HELLS/XBP1 7 GO:0003009 skeletal muscle contraction 1/389 45/18722 0.611697379081929 0.772726131455419 DMD 1 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 1/389 45/18722 0.611697379081929 0.772726131455419 STK25 1 GO:0010824 regulation of centrosome duplication 1/389 45/18722 0.611697379081929 0.772726131455419 CEP76 1 GO:0022602 ovulation cycle process 1/389 45/18722 0.611697379081929 0.772726131455419 ADAMTS1 1 GO:0030835 negative regulation of actin filament depolymerization 1/389 45/18722 0.611697379081929 0.772726131455419 LIMA1 1 GO:0035384 thioester biosynthetic process 1/389 45/18722 0.611697379081929 0.772726131455419 PDK2 1 GO:0044088 regulation of vacuole organization 1/389 45/18722 0.611697379081929 0.772726131455419 SCARB2 1 GO:0048599 oocyte development 1/389 45/18722 0.611697379081929 0.772726131455419 ZFX 1 GO:0071364 cellular response to epidermal growth factor stimulus 1/389 45/18722 0.611697379081929 0.772726131455419 EGFR 1 GO:0071616 acyl-CoA biosynthetic process 1/389 45/18722 0.611697379081929 0.772726131455419 PDK2 1 GO:0085029 extracellular matrix assembly 1/389 45/18722 0.611697379081929 0.772726131455419 DAG1 1 GO:2000273 positive regulation of signaling receptor activity 1/389 45/18722 0.611697379081929 0.772726131455419 NRP1 1 GO:0003300 cardiac muscle hypertrophy 2/389 99/18722 0.612847786854204 0.772840898567525 EZH2/IL6ST 2 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 2/389 99/18722 0.612847786854204 0.772840898567525 ABL1/AEN 2 GO:0021510 spinal cord development 2/389 99/18722 0.612847786854204 0.772840898567525 MPST/GLI3 2 GO:0042100 B cell proliferation 2/389 99/18722 0.612847786854204 0.772840898567525 TFRC/ABL1 2 GO:0060291 long-term synaptic potentiation 2/389 99/18722 0.612847786854204 0.772840898567525 ABL1/SERPINE2 2 GO:0051924 regulation of calcium ion transport 5/389 255/18722 0.613898317260627 0.773898086086936 GJA1/ABL1/TRIM27/CAMK2G/DMD 5 GO:0098754 detoxification 3/389 152/18722 0.614877433627722 0.774864547491465 TXNRD3/ATP7B/MT1A 3 GO:0071383 cellular response to steroid hormone stimulus 4/389 204/18722 0.615330808676322 0.775168034280673 YAP1/RBFOX2/EGFR/SKP2 4 GO:1903522 regulation of blood circulation 5/389 256/18722 0.617346808895523 0.777439161616703 GJA1/DOCK5/HMGCR/DMD/EGFR 5 GO:0009062 fatty acid catabolic process 2/389 100/18722 0.618321894971545 0.777556020939383 CPT1C/SLC27A2 2 GO:0061640 cytoskeleton-dependent cytokinesis 2/389 100/18722 0.618321894971545 0.777556020939383 RACGAP1/ARL3 2 GO:0007338 single fertilization 3/389 153/18722 0.619307817960746 0.777556020939383 UNC13B/UBXN8/KDM5B 3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 1/389 46/18722 0.61978485134927 0.777556020939383 TENM3 1 GO:0031057 negative regulation of histone modification 1/389 46/18722 0.61978485134927 0.777556020939383 WDR5 1 GO:0032924 activin receptor signaling pathway 1/389 46/18722 0.61978485134927 0.777556020939383 ACVR2A 1 GO:0035094 response to nicotine 1/389 46/18722 0.61978485134927 0.777556020939383 SLC7A11 1 GO:0042398 cellular modified amino acid biosynthetic process 1/389 46/18722 0.61978485134927 0.777556020939383 SLC7A11 1 GO:0045851 pH reduction 1/389 46/18722 0.61978485134927 0.777556020939383 CLN3 1 GO:0046839 phospholipid dephosphorylation 1/389 46/18722 0.61978485134927 0.777556020939383 SYNJ2 1 GO:1900271 regulation of long-term synaptic potentiation 1/389 46/18722 0.61978485134927 0.777556020939383 ABL1 1 GO:0051052 regulation of DNA metabolic process 7/389 359/18722 0.620298367054634 0.777932649466386 GJA1/TFRC/WRNIP1/MAGEF1/PCNA/BLM/EGFR 7 GO:0005996 monosaccharide metabolic process 5/389 257/18722 0.620777188922566 0.778265523547817 LRP5/PMM1/PDK2/SLC2A1/WDR5 5 GO:0017038 protein import 4/389 206/18722 0.622982109537432 0.780633699029482 RGPD5/CDH1/GLI3/NUP58 4 GO:0016052 carbohydrate catabolic process 3/389 154/18722 0.623703567190339 0.780633699029482 LRP5/SCARB2/ENOSF1 3 GO:0042102 positive regulation of T cell proliferation 2/389 101/18722 0.623736385788843 0.780633699029482 TFRC/IL6ST 2 GO:0048024 regulation of mRNA splicing, via spliceosome 2/389 101/18722 0.623736385788843 0.780633699029482 SRRM4/RBFOX2 2 GO:0051963 regulation of synapse assembly 2/389 101/18722 0.623736385788843 0.780633699029482 EPHB3/TPBG 2 GO:0009410 response to xenobiotic stimulus 9/389 462/18722 0.624764727017348 0.781043191994222 SLC1A3/FZD3/CDH1/DNMT3A/TFRC/BLMH/PCNA/GSTA4/EGFR 9 GO:0010799 regulation of peptidyl-threonine phosphorylation 1/389 47/18722 0.627704303738707 0.781043191994222 SPRED2 1 GO:0016073 snRNA metabolic process 1/389 47/18722 0.627704303738707 0.781043191994222 INTS1 1 GO:0019884 antigen processing and presentation of exogenous antigen 1/389 47/18722 0.627704303738707 0.781043191994222 CTSV 1 GO:0032008 positive regulation of TOR signaling 1/389 47/18722 0.627704303738707 0.781043191994222 SLC38A9 1 GO:0032369 negative regulation of lipid transport 1/389 47/18722 0.627704303738707 0.781043191994222 ITGAV 1 GO:0035315 hair cell differentiation 1/389 47/18722 0.627704303738707 0.781043191994222 ESRP1 1 GO:0035850 epithelial cell differentiation involved in kidney development 1/389 47/18722 0.627704303738707 0.781043191994222 YAP1 1 GO:0045581 negative regulation of T cell differentiation 1/389 47/18722 0.627704303738707 0.781043191994222 GLI3 1 GO:0045911 positive regulation of DNA recombination 1/389 47/18722 0.627704303738707 0.781043191994222 TFRC 1 GO:0050798 activated T cell proliferation 1/389 47/18722 0.627704303738707 0.781043191994222 ABL1 1 GO:0072583 clathrin-dependent endocytosis 1/389 47/18722 0.627704303738707 0.781043191994222 AAK1 1 GO:0090279 regulation of calcium ion import 1/389 47/18722 0.627704303738707 0.781043191994222 TRIM27 1 GO:0097028 dendritic cell differentiation 1/389 47/18722 0.627704303738707 0.781043191994222 AZI2 1 GO:0097300 programmed necrotic cell death 1/389 47/18722 0.627704303738707 0.781043191994222 SLC25A4 1 GO:0101023 vascular endothelial cell proliferation 1/389 47/18722 0.627704303738707 0.781043191994222 PPARG 1 GO:1905562 regulation of vascular endothelial cell proliferation 1/389 47/18722 0.627704303738707 0.781043191994222 PPARG 1 GO:0010522 regulation of calcium ion transport into cytosol 2/389 102/18722 0.629091366929395 0.781702287969848 ABL1/DMD 2 GO:0014897 striated muscle hypertrophy 2/389 102/18722 0.629091366929395 0.781702287969848 EZH2/IL6ST 2 GO:1902106 negative regulation of leukocyte differentiation 2/389 102/18722 0.629091366929395 0.781702287969848 GLI3/TRIB1 2 GO:1902749 regulation of cell cycle G2/M phase transition 2/389 102/18722 0.629091366929395 0.781702287969848 FZR1/BLM 2 GO:0002573 myeloid leukocyte differentiation 4/389 208/18722 0.63053698080725 0.783231733312003 PPARG/TFRC/TRIB1/CEBPA 4 GO:0035051 cardiocyte differentiation 3/389 156/18722 0.632390734875898 0.785067672235671 SGCB/FHL2/EGFR 3 GO:0070588 calcium ion transmembrane transport 6/389 312/18722 0.632516804945763 0.785067672235671 SLC35G1/ABL1/CHERP/DMD/ITGAV/ANO6 6 GO:0071222 cellular response to lipopolysaccharide 4/389 209/18722 0.634277957786769 0.785067672235671 ABL1/PLSCR4/TRIB1/XBP1 4 GO:0019395 fatty acid oxidation 2/389 103/18722 0.634386967239846 0.785067672235671 CPT1C/SLC27A2 2 GO:0032760 positive regulation of tumor necrosis factor production 2/389 103/18722 0.634386967239846 0.785067672235671 FZD5/SETD4 2 GO:0046425 regulation of receptor signaling pathway via JAK-STAT 2/389 103/18722 0.634386967239846 0.785067672235671 HGS/PRLR 2 GO:1905037 autophagosome organization 2/389 103/18722 0.634386967239846 0.785067672235671 TRAPPC8/CLN3 2 GO:0002673 regulation of acute inflammatory response 1/389 48/18722 0.635459218107952 0.785067672235671 IL6ST 1 GO:0010569 regulation of double-strand break repair via homologous recombination 1/389 48/18722 0.635459218107952 0.785067672235671 MAGEF1 1 GO:0015804 neutral amino acid transport 1/389 48/18722 0.635459218107952 0.785067672235671 SLC38A9 1 GO:0030261 chromosome condensation 1/389 48/18722 0.635459218107952 0.785067672235671 SMC2 1 GO:0044458 motile cilium assembly 1/389 48/18722 0.635459218107952 0.785067672235671 SPAG16 1 GO:0061647 histone H3-K9 modification 1/389 48/18722 0.635459218107952 0.785067672235671 SUV39H1 1 GO:0090311 regulation of protein deacetylation 1/389 48/18722 0.635459218107952 0.785067672235671 SPRED2 1 GO:1905710 positive regulation of membrane permeability 1/389 48/18722 0.635459218107952 0.785067672235671 JAM3 1 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 1/389 48/18722 0.635459218107952 0.785067672235671 STK3 1 GO:0072521 purine-containing compound metabolic process 8/389 416/18722 0.63723991456115 0.787001005216564 PDK2/TJP2/SLC26A2/HMGCR/SHMT1/ACSF2/MTHFD2L/COASY 8 GO:0002685 regulation of leukocyte migration 4/389 210/18722 0.637994483936357 0.787666175665502 JAM3/MMP14/PTK2/ANO6 4 GO:0006892 post-Golgi vesicle-mediated transport 2/389 104/18722 0.639623335866347 0.788837641049261 CLN3/ARL3 2 GO:0014896 muscle hypertrophy 2/389 104/18722 0.639623335866347 0.788837641049261 EZH2/IL6ST 2 GO:0002204 somatic recombination of immunoglobulin genes involved in immune response 1/389 49/18722 0.643053004343146 0.788837641049261 TFRC 1 GO:0002208 somatic diversification of immunoglobulins involved in immune response 1/389 49/18722 0.643053004343146 0.788837641049261 TFRC 1 GO:0002762 negative regulation of myeloid leukocyte differentiation 1/389 49/18722 0.643053004343146 0.788837641049261 TRIB1 1 GO:0006778 porphyrin-containing compound metabolic process 1/389 49/18722 0.643053004343146 0.788837641049261 COX10 1 GO:0007602 phototransduction 1/389 49/18722 0.643053004343146 0.788837641049261 CDS1 1 GO:0008206 bile acid metabolic process 1/389 49/18722 0.643053004343146 0.788837641049261 SLC27A2 1 GO:0009066 aspartate family amino acid metabolic process 1/389 49/18722 0.643053004343146 0.788837641049261 MTHFD2L 1 GO:0014075 response to amine 1/389 49/18722 0.643053004343146 0.788837641049261 GLDC 1 GO:0018198 peptidyl-cysteine modification 1/389 49/18722 0.643053004343146 0.788837641049261 DMD 1 GO:0021515 cell differentiation in spinal cord 1/389 49/18722 0.643053004343146 0.788837641049261 GLI3 1 GO:0045190 isotype switching 1/389 49/18722 0.643053004343146 0.788837641049261 TFRC 1 GO:0046580 negative regulation of Ras protein signal transduction 1/389 49/18722 0.643053004343146 0.788837641049261 MET 1 GO:0046605 regulation of centrosome cycle 1/389 49/18722 0.643053004343146 0.788837641049261 CEP76 1 GO:0048168 regulation of neuronal synaptic plasticity 1/389 49/18722 0.643053004343146 0.788837641049261 CLN3 1 GO:0070849 response to epidermal growth factor 1/389 49/18722 0.643053004343146 0.788837641049261 EGFR 1 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 1/389 49/18722 0.643053004343146 0.788837641049261 STK3 1 GO:1904894 positive regulation of receptor signaling pathway via STAT 1/389 49/18722 0.643053004343146 0.788837641049261 PRLR 1 GO:0016079 synaptic vesicle exocytosis 2/389 105/18722 0.644800641359773 0.790449727408099 UNC13B/SYT1 2 GO:0062207 regulation of pattern recognition receptor signaling pathway 2/389 105/18722 0.644800641359773 0.790449727408099 RAB7B/ANKRD17 2 GO:0006457 protein folding 4/389 212/18722 0.645353788454239 0.79059632734048 PPIL1/P3H1/ERO1B/FKBP4 4 GO:0030258 lipid modification 4/389 212/18722 0.645353788454239 0.79059632734048 SYNJ2/CPT1C/SLC27A2/MBOAT7 4 GO:0043271 negative regulation of ion transport 3/389 160/18722 0.649345410199428 0.791564970425802 GABRE/SERPINE2/TRIM27 3 GO:0060402 calcium ion transport into cytosol 3/389 160/18722 0.649345410199428 0.791564970425802 ABL1/CHERP/DMD 3 GO:0001824 blastocyst development 2/389 106/18722 0.649919070809203 0.791564970425802 ELF3/YAP1 2 GO:0007218 neuropeptide signaling pathway 2/389 106/18722 0.649919070809203 0.791564970425802 NPW/RAPGEF2 2 GO:0019882 antigen processing and presentation 2/389 106/18722 0.649919070809203 0.791564970425802 CTSV/RAB5B 2 GO:0035821 modulation of process of other organism 2/389 106/18722 0.649919070809203 0.791564970425802 DAG1/ANO6 2 GO:1903707 negative regulation of hemopoiesis 2/389 106/18722 0.649919070809203 0.791564970425802 GLI3/TRIB1 2 GO:2000278 regulation of DNA biosynthetic process 2/389 106/18722 0.649919070809203 0.791564970425802 GJA1/PCNA 2 GO:0006220 pyrimidine nucleotide metabolic process 1/389 50/18722 0.650489001842771 0.791564970425802 TDG 1 GO:0007080 mitotic metaphase plate congression 1/389 50/18722 0.650489001842771 0.791564970425802 CENPE 1 GO:0010665 regulation of cardiac muscle cell apoptotic process 1/389 50/18722 0.650489001842771 0.791564970425802 HMGCR 1 GO:0015872 dopamine transport 1/389 50/18722 0.650489001842771 0.791564970425802 SYT1 1 GO:0019083 viral transcription 1/389 50/18722 0.650489001842771 0.791564970425802 TRIM27 1 GO:0030490 maturation of SSU-rRNA 1/389 50/18722 0.650489001842771 0.791564970425802 RCL1 1 GO:0043268 positive regulation of potassium ion transport 1/389 50/18722 0.650489001842771 0.791564970425802 ANO6 1 GO:0045058 T cell selection 1/389 50/18722 0.650489001842771 0.791564970425802 GLI3 1 GO:0046638 positive regulation of alpha-beta T cell differentiation 1/389 50/18722 0.650489001842771 0.791564970425802 GLI3 1 GO:0051646 mitochondrion localization 1/389 50/18722 0.650489001842771 0.791564970425802 WASF1 1 GO:0070231 T cell apoptotic process 1/389 50/18722 0.650489001842771 0.791564970425802 GLI3 1 GO:1903747 regulation of establishment of protein localization to mitochondrion 1/389 50/18722 0.650489001842771 0.791564970425802 FZD5 1 GO:0070661 leukocyte proliferation 6/389 318/18722 0.650702435244462 0.791564970425802 TFRC/ABL1/AZI2/HELLS/PTK2/IL6ST 6 GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2/389 107/18722 0.654978829002854 0.795440489301835 FZD5/TFRC 2 GO:0005976 polysaccharide metabolic process 2/389 107/18722 0.654978829002854 0.795440489301835 GYG1/IL6ST 2 GO:0008637 apoptotic mitochondrial changes 2/389 107/18722 0.654978829002854 0.795440489301835 AIFM2/SLC25A4 2 GO:0036503 ERAD pathway 2/389 107/18722 0.654978829002854 0.795440489301835 UGGT2/UBXN8 2 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 2/389 107/18722 0.654978829002854 0.795440489301835 FZD5/SETD4 2 GO:0007601 visual perception 4/389 215/18722 0.656207062890966 0.796179536708068 ARL6/MYO9A/OPA3/WDR36 4 GO:0009895 negative regulation of catabolic process 6/389 320/18722 0.656641398724709 0.796179536708068 MET/LZTS1/LRIG2/HMGCR/SERPINE2/EGFR 6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone 1/389 51/18722 0.657770480971047 0.796179536708068 COQ9 1 GO:0010656 negative regulation of muscle cell apoptotic process 1/389 51/18722 0.657770480971047 0.796179536708068 HMGCR 1 GO:0032873 negative regulation of stress-activated MAPK cascade 1/389 51/18722 0.657770480971047 0.796179536708068 MARVELD3 1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 1/389 51/18722 0.657770480971047 0.796179536708068 ABL1 1 GO:0045104 intermediate filament cytoskeleton organization 1/389 51/18722 0.657770480971047 0.796179536708068 DST 1 GO:0045661 regulation of myoblast differentiation 1/389 51/18722 0.657770480971047 0.796179536708068 XKR8 1 GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 1/389 51/18722 0.657770480971047 0.796179536708068 MARVELD3 1 GO:1903307 positive regulation of regulated secretory pathway 1/389 51/18722 0.657770480971047 0.796179536708068 SYT1 1 GO:0050870 positive regulation of T cell activation 4/389 216/18722 0.659774999636244 0.797795015540144 GLI3/TFRC/IL6ST/XBP1 4 GO:0002832 negative regulation of response to biotic stimulus 2/389 108/18722 0.659980137615743 0.797795015540144 PPARG/TRIB1 2 GO:0033138 positive regulation of peptidyl-serine phosphorylation 2/389 108/18722 0.659980137615743 0.797795015540144 TFRC/EGFR 2 GO:0034440 lipid oxidation 2/389 108/18722 0.659980137615743 0.797795015540144 CPT1C/SLC27A2 2 GO:1903131 mononuclear cell differentiation 8/389 426/18722 0.663329600625707 0.801578215202768 FZD5/PPARG/GLI3/ABL1/MMP14/AZI2/EZH2/XBP1 8 GO:0010662 regulation of striated muscle cell apoptotic process 1/389 52/18722 0.664900644481425 0.802175003619503 HMGCR 1 GO:0035196 production of miRNAs involved in gene silencing by miRNA 1/389 52/18722 0.664900644481425 0.802175003619503 EGFR 1 GO:0045103 intermediate filament-based process 1/389 52/18722 0.664900644481425 0.802175003619503 DST 1 GO:0048260 positive regulation of receptor-mediated endocytosis 1/389 52/18722 0.664900644481425 0.802175003619503 AHI1 1 GO:0032414 positive regulation of ion transmembrane transporter activity 2/389 109/18722 0.664923234423295 0.802175003619503 TCAF1/DMD 2 GO:0002700 regulation of production of molecular mediator of immune response 3/389 164/18722 0.665737671730672 0.802891960582593 FZD5/TFRC/XBP1 3 GO:0007286 spermatid development 3/389 165/18722 0.669747666511444 0.805935709222747 PYGO1/JAM3/SPAG16 3 GO:0032635 interleukin-6 production 3/389 165/18722 0.669747666511444 0.805935709222747 RAB7B/SETD4/XBP1 3 GO:0032675 regulation of interleukin-6 production 3/389 165/18722 0.669747666511444 0.805935709222747 RAB7B/SETD4/XBP1 3 GO:0018958 phenol-containing compound metabolic process 2/389 110/18722 0.66980837254021 0.805935709222747 SLC7A11/RAPGEF2 2 GO:0032611 interleukin-1 beta production 2/389 110/18722 0.66980837254021 0.805935709222747 FZD5/NLRP2 2 GO:0032651 regulation of interleukin-1 beta production 2/389 110/18722 0.66980837254021 0.805935709222747 FZD5/NLRP2 2 GO:1905954 positive regulation of lipid localization 2/389 110/18722 0.66980837254021 0.805935709222747 PPARG/LRP1 2 GO:0034764 positive regulation of transmembrane transport 4/389 219/18722 0.670328465564437 0.806029645207221 ABL1/TCAF1/DMD/ANO6 4 GO:0050953 sensory perception of light stimulus 4/389 219/18722 0.670328465564437 0.806029645207221 ARL6/MYO9A/OPA3/WDR36 4 GO:0016925 protein sumoylation 1/389 53/18722 0.671882628910816 0.806038140670311 TRIM27 1 GO:0032784 regulation of DNA-templated transcription, elongation 1/389 53/18722 0.671882628910816 0.806038140670311 EZH2 1 GO:0033059 cellular pigmentation 1/389 53/18722 0.671882628910816 0.806038140670311 ARL6 1 GO:0043113 receptor clustering 1/389 53/18722 0.671882628910816 0.806038140670311 SLC7A11 1 GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 1/389 53/18722 0.671882628910816 0.806038140670311 MET 1 GO:0071320 cellular response to cAMP 1/389 53/18722 0.671882628910816 0.806038140670311 RAPGEF2 1 GO:2000772 regulation of cellular senescence 1/389 53/18722 0.671882628910816 0.806038140670311 ABL1 1 GO:0001938 positive regulation of endothelial cell proliferation 2/389 111/18722 0.674635819683853 0.809074920877018 EGFL7/NRP1 2 GO:0009451 RNA modification 3/389 167/18722 0.677661973737921 0.810507543609006 MRM1/RBM47/NSUN4 3 GO:0031960 response to corticosteroid 3/389 167/18722 0.677661973737921 0.810507543609006 CTSV/PCNA/EGFR 3 GO:0006968 cellular defense response 1/389 54/18722 0.678719505945134 0.810507543609006 DCDC2 1 GO:0007215 glutamate receptor signaling pathway 1/389 54/18722 0.678719505945134 0.810507543609006 CLN3 1 GO:0010524 positive regulation of calcium ion transport into cytosol 1/389 54/18722 0.678719505945134 0.810507543609006 ABL1 1 GO:0010659 cardiac muscle cell apoptotic process 1/389 54/18722 0.678719505945134 0.810507543609006 HMGCR 1 GO:0030834 regulation of actin filament depolymerization 1/389 54/18722 0.678719505945134 0.810507543609006 LIMA1 1 GO:0031050 dsRNA processing 1/389 54/18722 0.678719505945134 0.810507543609006 EGFR 1 GO:0060350 endochondral bone morphogenesis 1/389 54/18722 0.678719505945134 0.810507543609006 MMP14 1 GO:0070918 production of small RNA involved in gene silencing by RNA 1/389 54/18722 0.678719505945134 0.810507543609006 EGFR 1 GO:0086002 cardiac muscle cell action potential involved in contraction 1/389 54/18722 0.678719505945134 0.810507543609006 GJA1 1 GO:1902743 regulation of lamellipodium organization 1/389 54/18722 0.678719505945134 0.810507543609006 CYFIP1 1 GO:2000300 regulation of synaptic vesicle exocytosis 1/389 54/18722 0.678719505945134 0.810507543609006 SYT1 1 GO:0002526 acute inflammatory response 2/389 112/18722 0.679405857461501 0.810530965705624 IL6ST/ANO6 2 GO:0035601 protein deacylation 2/389 112/18722 0.679405857461501 0.810530965705624 SPRED2/ABHD12 2 GO:0046632 alpha-beta T cell differentiation 2/389 112/18722 0.679405857461501 0.810530965705624 GLI3/ABL1 2 GO:0015931 nucleobase-containing compound transport 4/389 222/18722 0.680655400364132 0.811756129865267 GJA1/NUP58/SLC25A4/MYO1C 4 GO:0016482 cytosolic transport 3/389 168/18722 0.681566322496987 0.812311234688402 RAB7B/CLN3/TRIM27 3 GO:0099173 postsynapse organization 3/389 168/18722 0.681566322496987 0.812311234688402 EPHB3/SLC7A11/NRP1 3 GO:0001578 microtubule bundle formation 2/389 113/18722 0.684118780680768 0.813466739886249 CLIP1/SPAG16 2 GO:0002708 positive regulation of lymphocyte mediated immunity 2/389 113/18722 0.684118780680768 0.813466739886249 FZD5/TFRC 2 GO:0044106 cellular amine metabolic process 2/389 113/18722 0.684118780680768 0.813466739886249 SLC7A11/CLN3 2 GO:0000768 syncytium formation by plasma membrane fusion 1/389 55/18722 0.685414283756755 0.813466739886249 MYOF 1 GO:0002067 glandular epithelial cell differentiation 1/389 55/18722 0.685414283756755 0.813466739886249 FGFR2 1 GO:0008333 endosome to lysosome transport 1/389 55/18722 0.685414283756755 0.813466739886249 RAB7B 1 GO:0010676 positive regulation of cellular carbohydrate metabolic process 1/389 55/18722 0.685414283756755 0.813466739886249 WDR5 1 GO:0044091 membrane biogenesis 1/389 55/18722 0.685414283756755 0.813466739886249 PEX11A 1 GO:0045620 negative regulation of lymphocyte differentiation 1/389 55/18722 0.685414283756755 0.813466739886249 GLI3 1 GO:0046164 alcohol catabolic process 1/389 55/18722 0.685414283756755 0.813466739886249 SYNJ2 1 GO:0061098 positive regulation of protein tyrosine kinase activity 1/389 55/18722 0.685414283756755 0.813466739886249 ERBB3 1 GO:0140253 cell-cell fusion 1/389 55/18722 0.685414283756755 0.813466739886249 MYOF 1 GO:0009152 purine ribonucleotide biosynthetic process 3/389 169/18722 0.685435506353289 0.813466739886249 PDK2/SLC26A2/COASY 3 GO:0022904 respiratory electron transport chain 2/389 114/18722 0.688774896682562 0.816439422718481 AIFM2/COQ9 2 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2/389 114/18722 0.688774896682562 0.816439422718481 PPARG/ACVR2A 2 GO:0022412 cellular process involved in reproduction in multicellular organism 7/389 384/18722 0.689075367459924 0.816439422718481 ASPM/LGR5/PYGO1/DNMT3A/JAM3/ZFX/SPAG16 7 GO:0007259 receptor signaling pathway via JAK-STAT 3/389 170/18722 0.689269564297933 0.816439422718481 HGS/PRLR/IL6ST 3 GO:1902105 regulation of leukocyte differentiation 5/389 279/18722 0.691467703333789 0.816439422718481 GLI3/ABL1/MMP14/TRIB1/XBP1 5 GO:0002090 regulation of receptor internalization 1/389 56/18722 0.691969908314457 0.816439422718481 AHI1 1 GO:0002711 positive regulation of T cell mediated immunity 1/389 56/18722 0.691969908314457 0.816439422718481 FZD5 1 GO:0010658 striated muscle cell apoptotic process 1/389 56/18722 0.691969908314457 0.816439422718481 HMGCR 1 GO:0032608 interferon-beta production 1/389 56/18722 0.691969908314457 0.816439422718481 POLR3F 1 GO:0032648 regulation of interferon-beta production 1/389 56/18722 0.691969908314457 0.816439422718481 POLR3F 1 GO:0043388 positive regulation of DNA binding 1/389 56/18722 0.691969908314457 0.816439422718481 PPARG 1 GO:0043470 regulation of carbohydrate catabolic process 1/389 56/18722 0.691969908314457 0.816439422718481 SCARB2 1 GO:0050433 regulation of catecholamine secretion 1/389 56/18722 0.691969908314457 0.816439422718481 SYT1 1 GO:0051058 negative regulation of small GTPase mediated signal transduction 1/389 56/18722 0.691969908314457 0.816439422718481 MET 1 GO:0055078 sodium ion homeostasis 1/389 56/18722 0.691969908314457 0.816439422718481 SLC1A3 1 GO:0070534 protein K63-linked ubiquitination 1/389 56/18722 0.691969908314457 0.816439422718481 TRIM27 1 GO:0071385 cellular response to glucocorticoid stimulus 1/389 56/18722 0.691969908314457 0.816439422718481 EGFR 1 GO:0098781 ncRNA transcription 1/389 56/18722 0.691969908314457 0.816439422718481 IPPK 1 GO:0000077 DNA damage checkpoint signaling 2/389 115/18722 0.693374524695935 0.817039383381608 FZR1/BLM 2 GO:0042471 ear morphogenesis 2/389 115/18722 0.693374524695935 0.817039383381608 FZD3/FGFR2 2 GO:0071675 regulation of mononuclear cell migration 2/389 115/18722 0.693374524695935 0.817039383381608 PTK2/ANO6 2 GO:0090630 activation of GTPase activity 2/389 115/18722 0.693374524695935 0.817039383381608 RUNDC1/EPHA1 2 GO:0000280 nuclear division 8/389 439/18722 0.69553311487299 0.817927311573032 ASPM/MAP10/CENPE/LRP5/KIF11/RACGAP1/FZR1/SMC2 8 GO:0042113 B cell activation 6/389 334/18722 0.696440145354635 0.817927311573032 IGLL1/TFRC/ABL1/MMP14/EZH2/XBP1 6 GO:0002221 pattern recognition receptor signaling pathway 3/389 172/18722 0.69683249777001 0.817927311573032 RAB7B/ANKRD17/IRAK4 3 GO:0048515 spermatid differentiation 3/389 172/18722 0.69683249777001 0.817927311573032 PYGO1/JAM3/SPAG16 3 GO:0098813 nuclear chromosome segregation 5/389 281/18722 0.697426917551935 0.817927311573032 MAP10/CENPE/RACGAP1/SMC2/DYNC1H1 5 GO:0031123 RNA 3'-end processing 2/389 116/18722 0.697917995214208 0.817927311573032 INTS1/ELAC2 2 GO:0035967 cellular response to topologically incorrect protein 2/389 116/18722 0.697917995214208 0.817927311573032 UGGT2/XBP1 2 GO:0098732 macromolecule deacylation 2/389 116/18722 0.697917995214208 0.817927311573032 SPRED2/ABHD12 2 GO:0006695 cholesterol biosynthetic process 1/389 57/18722 0.698389264666417 0.817927311573032 HMGCR 1 GO:0006949 syncytium formation 1/389 57/18722 0.698389264666417 0.817927311573032 MYOF 1 GO:0016447 somatic recombination of immunoglobulin gene segments 1/389 57/18722 0.698389264666417 0.817927311573032 TFRC 1 GO:0030219 megakaryocyte differentiation 1/389 57/18722 0.698389264666417 0.817927311573032 RAB7B 1 GO:0050879 multicellular organismal movement 1/389 57/18722 0.698389264666417 0.817927311573032 DMD 1 GO:0050881 musculoskeletal movement 1/389 57/18722 0.698389264666417 0.817927311573032 DMD 1 GO:0051155 positive regulation of striated muscle cell differentiation 1/389 57/18722 0.698389264666417 0.817927311573032 MMP14 1 GO:0051289 protein homotetramerization 1/389 57/18722 0.698389264666417 0.817927311573032 SHMT1 1 GO:0051785 positive regulation of nuclear division 1/389 57/18722 0.698389264666417 0.817927311573032 LRP5 1 GO:0097120 receptor localization to synapse 1/389 57/18722 0.698389264666417 0.817927311573032 DAG1 1 GO:1902653 secondary alcohol biosynthetic process 1/389 57/18722 0.698389264666417 0.817927311573032 HMGCR 1 GO:0006694 steroid biosynthetic process 3/389 173/18722 0.700561489956622 0.820207946668315 SLC27A2/HMGCR/PRLR 3 GO:0001659 temperature homeostasis 3/389 174/18722 0.704255589107246 0.821858130759118 GJA1/DYNC1H1/PRLR 3 GO:0002763 positive regulation of myeloid leukocyte differentiation 1/389 58/18722 0.704675178196809 0.821858130759118 TRIB1 1 GO:0002931 response to ischemia 1/389 58/18722 0.704675178196809 0.821858130759118 GJA1 1 GO:0006826 iron ion transport 1/389 58/18722 0.704675178196809 0.821858130759118 TFRC 1 GO:0009161 ribonucleoside monophosphate metabolic process 1/389 58/18722 0.704675178196809 0.821858130759118 TJP2 1 GO:0010043 response to zinc ion 1/389 58/18722 0.704675178196809 0.821858130759118 MT1A 1 GO:0032481 positive regulation of type I interferon production 1/389 58/18722 0.704675178196809 0.821858130759118 POLR3F 1 GO:0042743 hydrogen peroxide metabolic process 1/389 58/18722 0.704675178196809 0.821858130759118 EGFR 1 GO:0043506 regulation of JUN kinase activity 1/389 58/18722 0.704675178196809 0.821858130759118 FZD5 1 GO:0050432 catecholamine secretion 1/389 58/18722 0.704675178196809 0.821858130759118 SYT1 1 GO:0086065 cell communication involved in cardiac conduction 1/389 58/18722 0.704675178196809 0.821858130759118 GJA1 1 GO:2000649 regulation of sodium ion transmembrane transporter activity 1/389 58/18722 0.704675178196809 0.821858130759118 DMD 1 GO:0009308 amine metabolic process 2/389 118/18722 0.706837838460998 0.824116878793881 SLC7A11/CLN3 2 GO:0022900 electron transport chain 3/389 175/18722 0.707914871561887 0.82510883240211 AIFM2/GLDC/COQ9 3 GO:0002820 negative regulation of adaptive immune response 1/389 59/18722 0.710830415856551 0.827185235044302 TRIM27 1 GO:0019369 arachidonic acid metabolic process 1/389 59/18722 0.710830415856551 0.827185235044302 ABHD12 1 GO:0030042 actin filament depolymerization 1/389 59/18722 0.710830415856551 0.827185235044302 LIMA1 1 GO:0043551 regulation of phosphatidylinositol 3-kinase activity 1/389 59/18722 0.710830415856551 0.827185235044302 PTK2 1 GO:0051353 positive regulation of oxidoreductase activity 1/389 59/18722 0.710830415856551 0.827185235044302 ABL1 1 GO:0010906 regulation of glucose metabolic process 2/389 119/18722 0.711214923168602 0.82736868414542 PDK2/WDR5 2 GO:0030218 erythrocyte differentiation 2/389 120/18722 0.715537273231064 0.831810367748572 ACVR2A/RBFOX2 2 GO:0032411 positive regulation of transporter activity 2/389 120/18722 0.715537273231064 0.831810367748572 TCAF1/DMD 2 GO:0002712 regulation of B cell mediated immunity 1/389 60/18722 0.716857687368731 0.831810367748572 TFRC 1 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 1/389 60/18722 0.716857687368731 0.831810367748572 ANKRD17 1 GO:0002889 regulation of immunoglobulin mediated immune response 1/389 60/18722 0.716857687368731 0.831810367748572 TFRC 1 GO:0030071 regulation of mitotic metaphase/anaphase transition 1/389 60/18722 0.716857687368731 0.831810367748572 CENPE 1 GO:0031663 lipopolysaccharide-mediated signaling pathway 1/389 60/18722 0.716857687368731 0.831810367748572 TRIB1 1 GO:0061951 establishment of protein localization to plasma membrane 1/389 60/18722 0.716857687368731 0.831810367748572 CLN3 1 GO:0046651 lymphocyte proliferation 5/389 288/18722 0.717658111102796 0.832474278368924 TFRC/ABL1/AZI2/HELLS/IL6ST 5 GO:0006109 regulation of carbohydrate metabolic process 3/389 178/18722 0.718684683170561 0.833400012566943 PDK2/SCARB2/WDR5 3 GO:0006163 purine nucleotide metabolic process 7/389 396/18722 0.719098420769655 0.833614729989489 PDK2/TJP2/SLC26A2/HMGCR/ACSF2/MTHFD2L/COASY 7 GO:0002224 toll-like receptor signaling pathway 2/389 121/18722 0.719805266808392 0.83390400509854 RAB7B/IRAK4 2 GO:0043244 regulation of protein-containing complex disassembly 2/389 121/18722 0.719805266808392 0.83390400509854 CLN3/LIMA1 2 GO:0006399 tRNA metabolic process 3/389 179/18722 0.722205595488688 0.83548496061784 TARS2/HARS2/ELAC2 3 GO:0006900 vesicle budding from membrane 1/389 61/18722 0.722759646409217 0.83548496061784 SEC24C 1 GO:0043030 regulation of macrophage activation 1/389 61/18722 0.722759646409217 0.83548496061784 CEBPA 1 GO:0043966 histone H3 acetylation 1/389 61/18722 0.722759646409217 0.83548496061784 WDR5 1 GO:0060997 dendritic spine morphogenesis 1/389 61/18722 0.722759646409217 0.83548496061784 EPHB3 1 GO:0071384 cellular response to corticosteroid stimulus 1/389 61/18722 0.722759646409217 0.83548496061784 EGFR 1 GO:0002699 positive regulation of immune effector process 4/389 235/18722 0.722773526391359 0.83548496061784 FZD5/TFRC/ANKRD17/XBP1 4 GO:0072329 monocarboxylic acid catabolic process 2/389 122/18722 0.724019289995815 0.836394789551707 CPT1C/SLC27A2 2 GO:1990266 neutrophil migration 2/389 122/18722 0.724019289995815 0.836394789551707 JAM3/IRAK4 2 GO:0003012 muscle system process 8/389 452/18722 0.725717679931542 0.837921187462374 GJA1/DAG1/DOCK5/MYOF/CAMK2G/EZH2/DMD/IL6ST 8 GO:0016236 macroautophagy 5/389 291/18722 0.726029874521826 0.837921187462374 LZTS1/HGS/TRAPPC8/CLN3/SLC25A4 5 GO:0032943 mononuclear cell proliferation 5/389 291/18722 0.726029874521826 0.837921187462374 TFRC/ABL1/AZI2/HELLS/IL6ST 5 GO:0003231 cardiac ventricle development 2/389 123/18722 0.728179736332849 0.838068098997185 LRP2/FGFR2 2 GO:0031570 DNA integrity checkpoint signaling 2/389 123/18722 0.728179736332849 0.838068098997185 FZR1/BLM 2 GO:0002260 lymphocyte homeostasis 1/389 62/18722 0.728538891762993 0.838068098997185 ABL1 1 GO:0007091 metaphase/anaphase transition of mitotic cell cycle 1/389 62/18722 0.728538891762993 0.838068098997185 CENPE 1 GO:0007588 excretion 1/389 62/18722 0.728538891762993 0.838068098997185 CLN3 1 GO:0019933 cAMP-mediated signaling 1/389 62/18722 0.728538891762993 0.838068098997185 RAPGEF2 1 GO:0046173 polyol biosynthetic process 1/389 62/18722 0.728538891762993 0.838068098997185 IPPK 1 GO:0048002 antigen processing and presentation of peptide antigen 1/389 62/18722 0.728538891762993 0.838068098997185 CTSV 1 GO:0060113 inner ear receptor cell differentiation 1/389 62/18722 0.728538891762993 0.838068098997185 ESRP1 1 GO:0070265 necrotic cell death 1/389 62/18722 0.728538891762993 0.838068098997185 SLC25A4 1 GO:0019318 hexose metabolic process 4/389 237/18722 0.728874002692182 0.838068098997185 LRP5/PMM1/PDK2/WDR5 4 GO:0032640 tumor necrosis factor production 3/389 181/18722 0.729144523750499 0.838068098997185 FZD5/TRIM27/SETD4 3 GO:0032680 regulation of tumor necrosis factor production 3/389 181/18722 0.729144523750499 0.838068098997185 FZD5/TRIM27/SETD4 3 GO:0010508 positive regulation of autophagy 2/389 124/18722 0.732287006329244 0.840961052437661 TRIM27/SLC25A4 2 GO:0009260 ribonucleotide biosynthetic process 3/389 182/18722 0.732562773677009 0.840961052437661 PDK2/SLC26A2/COASY 3 GO:0051260 protein homooligomerization 3/389 182/18722 0.732562773677009 0.840961052437661 SIGMAR1/BLM/SHMT1 3 GO:0001756 somitogenesis 1/389 63/18722 0.73419796845668 0.840961052437661 COBL 1 GO:0001947 heart looping 1/389 63/18722 0.73419796845668 0.840961052437661 AHI1 1 GO:0016239 positive regulation of macroautophagy 1/389 63/18722 0.73419796845668 0.840961052437661 SLC25A4 1 GO:0046902 regulation of mitochondrial membrane permeability 1/389 63/18722 0.73419796845668 0.840961052437661 SLC25A4 1 GO:0050854 regulation of antigen receptor-mediated signaling pathway 1/389 63/18722 0.73419796845668 0.840961052437661 PRKCH 1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 1/389 63/18722 0.73419796845668 0.840961052437661 XBP1 1 GO:1902099 regulation of metaphase/anaphase transition of cell cycle 1/389 63/18722 0.73419796845668 0.840961052437661 CENPE 1 GO:2000242 negative regulation of reproductive process 1/389 63/18722 0.73419796845668 0.840961052437661 GJA1 1 GO:1903039 positive regulation of leukocyte cell-cell adhesion 4/389 239/18722 0.734873946193353 0.84147104608074 GLI3/TFRC/IL6ST/XBP1 4 GO:0018210 peptidyl-threonine modification 2/389 125/18722 0.736341507007321 0.842358053969793 SPRED2/GALNT11 2 GO:0055007 cardiac muscle cell differentiation 2/389 125/18722 0.736341507007321 0.842358053969793 SGCB/FHL2 2 GO:0071621 granulocyte chemotaxis 2/389 125/18722 0.736341507007321 0.842358053969793 JAM3/PTK2 2 GO:0006940 regulation of smooth muscle contraction 1/389 64/18722 0.739739368867761 0.844391073008051 DOCK5 1 GO:0016126 sterol biosynthetic process 1/389 64/18722 0.739739368867761 0.844391073008051 HMGCR 1 GO:0030837 negative regulation of actin filament polymerization 1/389 64/18722 0.739739368867761 0.844391073008051 KANK4 1 GO:0030888 regulation of B cell proliferation 1/389 64/18722 0.739739368867761 0.844391073008051 TFRC 1 GO:0032507 maintenance of protein location in cell 1/389 64/18722 0.739739368867761 0.844391073008051 GJA1 1 GO:0048857 neural nucleus development 1/389 64/18722 0.739739368867761 0.844391073008051 NDRG2 1 GO:0070542 response to fatty acid 1/389 64/18722 0.739739368867761 0.844391073008051 GLDC 1 GO:0043433 negative regulation of DNA-binding transcription factor activity 3/389 185/18722 0.742614184552571 0.847142299362911 TRIB1/EZH2/NLRP2 3 GO:0140013 meiotic nuclear division 3/389 185/18722 0.742614184552571 0.847142299362911 ASPM/FZR1/SMC2 3 GO:0030048 actin filament-based movement 2/389 127/18722 0.744293858425712 0.847930952202376 GJA1/MYO1C 2 GO:0002720 positive regulation of cytokine production involved in immune response 1/389 65/18722 0.745165533810972 0.847930952202376 FZD5 1 GO:0010965 regulation of mitotic sister chromatid separation 1/389 65/18722 0.745165533810972 0.847930952202376 CENPE 1 GO:0033692 cellular polysaccharide biosynthetic process 1/389 65/18722 0.745165533810972 0.847930952202376 GYG1 1 GO:0035418 protein localization to synapse 1/389 65/18722 0.745165533810972 0.847930952202376 DAG1 1 GO:0044784 metaphase/anaphase transition of cell cycle 1/389 65/18722 0.745165533810972 0.847930952202376 CENPE 1 GO:0046503 glycerolipid catabolic process 1/389 65/18722 0.745165533810972 0.847930952202376 ABHD12 1 GO:0071677 positive regulation of mononuclear cell migration 1/389 65/18722 0.745165533810972 0.847930952202376 ANO6 1 GO:0052547 regulation of peptidase activity 8/389 461/18722 0.745404223851734 0.847937992634833 PPARG/CLDN4/LRP1/CLDN3/SERPINE2/ITIH5/SPINT1/NLRP2 8 GO:0071706 tumor necrosis factor superfamily cytokine production 3/389 186/18722 0.745897326810121 0.84796993481188 FZD5/TRIM27/SETD4 3 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 3/389 186/18722 0.745897326810121 0.84796993481188 FZD5/TRIM27/SETD4 3 GO:0006639 acylglycerol metabolic process 2/389 128/18722 0.74819255187474 0.849784564524191 MBOAT7/ABHD12 2 GO:0032612 interleukin-1 production 2/389 128/18722 0.74819255187474 0.849784564524191 FZD5/NLRP2 2 GO:0032652 regulation of interleukin-1 production 2/389 128/18722 0.74819255187474 0.849784564524191 FZD5/NLRP2 2 GO:0002696 positive regulation of leukocyte activation 7/389 409/18722 0.749347837312893 0.850527153228009 IGLL1/GLI3/TFRC/MMP14/CEBPA/IL6ST/XBP1 7 GO:0006325 chromatin organization 7/389 409/18722 0.749347837312893 0.850527153228009 DNMT3A/SMARCA1/KDM5B/SUV39H1/TDG/EZH2/HELLS 7 GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 1/389 66/18722 0.750478853602339 0.850527153228009 TFRC 1 GO:0016444 somatic cell DNA recombination 1/389 66/18722 0.750478853602339 0.850527153228009 TFRC 1 GO:0046626 regulation of insulin receptor signaling pathway 1/389 66/18722 0.750478853602339 0.850527153228009 SIK2 1 GO:2000272 negative regulation of signaling receptor activity 1/389 66/18722 0.750478853602339 0.850527153228009 PPARG 1 GO:2000573 positive regulation of DNA biosynthetic process 1/389 66/18722 0.750478853602339 0.850527153228009 PCNA 1 GO:0006638 neutral lipid metabolic process 2/389 129/18722 0.752040160614918 0.851238505823279 MBOAT7/ABHD12 2 GO:0007093 mitotic cell cycle checkpoint signaling 2/389 129/18722 0.752040160614918 0.851238505823279 FZR1/BLM 2 GO:0034101 erythrocyte homeostasis 2/389 129/18722 0.752040160614918 0.851238505823279 ACVR2A/RBFOX2 2 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 2/389 129/18722 0.752040160614918 0.851238505823279 PPARG/NLRP2 2 GO:0006814 sodium ion transport 4/389 245/18722 0.752274503802977 0.851239564185373 SERPINE2/PRSS8/DMD/ANO6 4 GO:0006879 cellular iron ion homeostasis 1/389 67/18722 0.755681669101304 0.852098290265856 TFRC 1 GO:0009583 detection of light stimulus 1/389 67/18722 0.755681669101304 0.852098290265856 CDS1 1 GO:0016445 somatic diversification of immunoglobulins 1/389 67/18722 0.755681669101304 0.852098290265856 TFRC 1 GO:0035914 skeletal muscle cell differentiation 1/389 67/18722 0.755681669101304 0.852098290265856 GPC1 1 GO:0042490 mechanoreceptor differentiation 1/389 67/18722 0.755681669101304 0.852098290265856 ESRP1 1 GO:0043967 histone H4 acetylation 1/389 67/18722 0.755681669101304 0.852098290265856 WDR5 1 GO:0046635 positive regulation of alpha-beta T cell activation 1/389 67/18722 0.755681669101304 0.852098290265856 GLI3 1 GO:0051306 mitotic sister chromatid separation 1/389 67/18722 0.755681669101304 0.852098290265856 CENPE 1 GO:0061371 determination of heart left/right asymmetry 1/389 67/18722 0.755681669101304 0.852098290265856 AHI1 1 GO:1902117 positive regulation of organelle assembly 1/389 67/18722 0.755681669101304 0.852098290265856 DYNC1H1 1 GO:0030534 adult behavior 2/389 130/18722 0.755837117907881 0.852098290265856 SLC7A11/ABHD12 2 GO:0051028 mRNA transport 2/389 130/18722 0.755837117907881 0.852098290265856 NUP58/MYO1C 2 GO:0046390 ribose phosphate biosynthetic process 3/389 190/18722 0.758697153264329 0.855023441186886 PDK2/SLC26A2/COASY 3 GO:0000723 telomere maintenance 2/389 131/18722 0.759583861100499 0.855023441186886 PCNA/BLM 2 GO:0009247 glycolipid biosynthetic process 1/389 68/18722 0.760776272731408 0.855023441186886 PIGV 1 GO:0042267 natural killer cell mediated cytotoxicity 1/389 68/18722 0.760776272731408 0.855023441186886 RNF19B 1 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 1/389 68/18722 0.760776272731408 0.855023441186886 IL6ST 1 GO:0042987 amyloid precursor protein catabolic process 1/389 68/18722 0.760776272731408 0.855023441186886 CLN3 1 GO:0046637 regulation of alpha-beta T cell differentiation 1/389 68/18722 0.760776272731408 0.855023441186886 GLI3 1 GO:0051926 negative regulation of calcium ion transport 1/389 68/18722 0.760776272731408 0.855023441186886 TRIM27 1 GO:0061912 selective autophagy 1/389 68/18722 0.760776272731408 0.855023441186886 SLC25A4 1 GO:1902305 regulation of sodium ion transmembrane transport 1/389 68/18722 0.760776272731408 0.855023441186886 DMD 1 GO:0007569 cell aging 2/389 132/18722 0.763280831269387 0.857421690891547 ABL1/FZR1 2 GO:1901988 negative regulation of cell cycle phase transition 4/389 249/18722 0.763380375740294 0.857421690891547 DCUN1D3/FZR1/BLM/EZH2 4 GO:0006368 transcription elongation from RNA polymerase II promoter 1/389 69/18722 0.76576490947996 0.858513564363177 EZH2 1 GO:0010611 regulation of cardiac muscle hypertrophy 1/389 69/18722 0.76576490947996 0.858513564363177 IL6ST 1 GO:0019226 transmission of nerve impulse 1/389 69/18722 0.76576490947996 0.858513564363177 JAM3 1 GO:0031060 regulation of histone methylation 1/389 69/18722 0.76576490947996 0.858513564363177 WDR5 1 GO:0070192 chromosome organization involved in meiotic cell cycle 1/389 69/18722 0.76576490947996 0.858513564363177 SMC2 1 GO:1901224 positive regulation of NIK/NF-kappaB signaling 1/389 69/18722 0.76576490947996 0.858513564363177 EGFR 1 GO:0051251 positive regulation of lymphocyte activation 6/389 362/18722 0.766444800385651 0.85901173540457 IGLL1/GLI3/TFRC/MMP14/IL6ST/XBP1 6 GO:0006997 nucleus organization 2/389 133/18722 0.766928472878362 0.85928975133253 PYGO1/SUV39H1 2 GO:0002705 positive regulation of leukocyte mediated immunity 2/389 134/18722 0.770527233448459 0.861870512087663 FZD5/TFRC 2 GO:0032147 activation of protein kinase activity 2/389 134/18722 0.770527233448459 0.861870512087663 ABL1/PRLR 2 GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response 1/389 70/18722 0.770649777877124 0.861870512087663 TFRC 1 GO:0002548 monocyte chemotaxis 1/389 70/18722 0.770649777877124 0.861870512087663 ANO6 1 GO:0003407 neural retina development 1/389 70/18722 0.770649777877124 0.861870512087663 AHI1 1 GO:0045123 cellular extravasation 1/389 70/18722 0.770649777877124 0.861870512087663 JAM3 1 GO:0002285 lymphocyte activation involved in immune response 3/389 194/18722 0.77097222767126 0.861966803898555 TFRC/ABL1/XBP1 3 GO:0050867 positive regulation of cell activation 7/389 420/18722 0.773086055807861 0.864065230012648 IGLL1/GLI3/TFRC/MMP14/CEBPA/IL6ST/XBP1 7 GO:0002228 natural killer cell mediated immunity 1/389 71/18722 0.775433030954852 0.865097664084536 RNF19B 1 GO:0008344 adult locomotory behavior 1/389 71/18722 0.775433030954852 0.865097664084536 ABHD12 1 GO:0032722 positive regulation of chemokine production 1/389 71/18722 0.775433030954852 0.865097664084536 LRP1 1 GO:0033555 multicellular organismal response to stress 1/389 71/18722 0.775433030954852 0.865097664084536 GJA1 1 GO:0043550 regulation of lipid kinase activity 1/389 71/18722 0.775433030954852 0.865097664084536 PTK2 1 GO:0045824 negative regulation of innate immune response 1/389 71/18722 0.775433030954852 0.865097664084536 PPARG 1 GO:0009165 nucleotide biosynthetic process 4/389 254/18722 0.776714788362539 0.866222569929249 PDK2/SLC26A2/MTHFD2L/COASY 4 GO:0006006 glucose metabolic process 3/389 196/18722 0.776916376813428 0.866222569929249 LRP5/PDK2/WDR5 3 GO:0072594 establishment of protein localization to organelle 7/389 422/18722 0.777220115770644 0.866296382095214 RGPD5/FZD5/CDH1/GLI3/HGS/SCARB2/NUP58 7 GO:0043624 cellular protein complex disassembly 2/389 136/18722 0.777579914947228 0.866432615280336 MTRF1L/LIMA1 2 GO:0009150 purine ribonucleotide metabolic process 6/389 368/18722 0.77977481057033 0.866575512378823 PDK2/TJP2/SLC26A2/HMGCR/ACSF2/COASY 6 GO:0000271 polysaccharide biosynthetic process 1/389 72/18722 0.780116777186077 0.866575512378823 GYG1 1 GO:0014743 regulation of muscle hypertrophy 1/389 72/18722 0.780116777186077 0.866575512378823 IL6ST 1 GO:0030032 lamellipodium assembly 1/389 72/18722 0.780116777186077 0.866575512378823 CYFIP1 1 GO:0030330 DNA damage response, signal transduction by p53 class mediator 1/389 72/18722 0.780116777186077 0.866575512378823 SPRED2 1 GO:0033045 regulation of sister chromatid segregation 1/389 72/18722 0.780116777186077 0.866575512378823 CENPE 1 GO:0042273 ribosomal large subunit biogenesis 1/389 72/18722 0.780116777186077 0.866575512378823 RPF1 1 GO:0070227 lymphocyte apoptotic process 1/389 72/18722 0.780116777186077 0.866575512378823 GLI3 1 GO:1901880 negative regulation of protein depolymerization 1/389 72/18722 0.780116777186077 0.866575512378823 LIMA1 1 GO:1905818 regulation of chromosome separation 1/389 72/18722 0.780116777186077 0.866575512378823 CENPE 1 GO:0050671 positive regulation of lymphocyte proliferation 2/389 137/18722 0.781034743402575 0.866575512378823 TFRC/IL6ST 2 GO:0050684 regulation of mRNA processing 2/389 137/18722 0.781034743402575 0.866575512378823 SRRM4/RBFOX2 2 GO:0060048 cardiac muscle contraction 2/389 137/18722 0.781034743402575 0.866575512378823 GJA1/DMD 2 GO:0060078 regulation of postsynaptic membrane potential 2/389 137/18722 0.781034743402575 0.866575512378823 GABRE/UNC13B 2 GO:0034976 response to endoplasmic reticulum stress 4/389 256/18722 0.781880309101697 0.866986162144691 UGGT2/UBXN8/TMTC3/XBP1 4 GO:1901293 nucleoside phosphate biosynthetic process 4/389 256/18722 0.781880309101697 0.866986162144691 PDK2/SLC26A2/MTHFD2L/COASY 4 GO:0030217 T cell differentiation 4/389 257/18722 0.784427394005715 0.86800489471714 FZD5/GLI3/ABL1/XBP1 4 GO:0032946 positive regulation of mononuclear cell proliferation 2/389 138/18722 0.784442505294505 0.86800489471714 TFRC/IL6ST 2 GO:0009166 nucleotide catabolic process 1/389 73/18722 0.784703081404555 0.86800489471714 TDG 1 GO:0042274 ribosomal small subunit biogenesis 1/389 73/18722 0.784703081404555 0.86800489471714 RCL1 1 GO:0051865 protein autoubiquitination 1/389 73/18722 0.784703081404555 0.86800489471714 RNF19B 1 GO:0051937 catecholamine transport 1/389 73/18722 0.784703081404555 0.86800489471714 SYT1 1 GO:0086003 cardiac muscle cell contraction 1/389 73/18722 0.784703081404555 0.86800489471714 GJA1 1 GO:1904427 positive regulation of calcium ion transmembrane transport 1/389 73/18722 0.784703081404555 0.86800489471714 ABL1 1 GO:0006323 DNA packaging 3/389 199/18722 0.78559493486453 0.868464603652907 SUV39H1/SMC2/HELLS 3 GO:0042098 T cell proliferation 3/389 199/18722 0.78559493486453 0.868464603652907 TFRC/ABL1/IL6ST 3 GO:0030216 keratinocyte differentiation 2/389 139/18722 0.787803658894316 0.870378656161033 PRKCH/YAP1 2 GO:0051783 regulation of nuclear division 2/389 139/18722 0.787803658894316 0.870378656161033 LRP5/FZR1 2 GO:0006801 superoxide metabolic process 1/389 74/18722 0.789193965705784 0.870596005120688 EGFR 1 GO:0030968 endoplasmic reticulum unfolded protein response 1/389 74/18722 0.789193965705784 0.870596005120688 XBP1 1 GO:0046323 glucose import 1/389 74/18722 0.789193965705784 0.870596005120688 SLC2A1 1 GO:0051881 regulation of mitochondrial membrane potential 1/389 74/18722 0.789193965705784 0.870596005120688 ABL1 1 GO:0070972 protein localization to endoplasmic reticulum 1/389 74/18722 0.789193965705784 0.870596005120688 GJA1 1 GO:0046165 alcohol biosynthetic process 2/389 140/18722 0.79111866379415 0.872308161313148 IPPK/HMGCR 2 GO:0051054 positive regulation of DNA metabolic process 3/389 201/18722 0.79122440296789 0.872308161313148 TFRC/PCNA/EGFR 3 GO:0030098 lymphocyte differentiation 6/389 374/18722 0.792525406186413 0.873478439517029 FZD5/GLI3/ABL1/MMP14/EZH2/XBP1 6 GO:0015980 energy derivation by oxidation of organic compounds 5/389 318/18722 0.793393433003914 0.873861072907964 AIFM2/COX10/GYG1/IL6ST/COQ9 5 GO:0034121 regulation of toll-like receptor signaling pathway 1/389 75/18722 0.79359141032936 0.873861072907964 RAB7B 1 GO:0045913 positive regulation of carbohydrate metabolic process 1/389 75/18722 0.79359141032936 0.873861072907964 WDR5 1 GO:1903046 meiotic cell cycle process 3/389 202/18722 0.793992849320046 0.874039215656567 ASPM/FZR1/SMC2 3 GO:0090305 nucleic acid phosphodiester bond hydrolysis 4/389 261/18722 0.79438025755039 0.874201810285538 RCL1/TSN/AEN/ELAC2 4 GO:0010466 negative regulation of peptidase activity 4/389 262/18722 0.796810131474479 0.876485437333128 LRP1/SERPINE2/ITIH5/SPINT1 4 GO:0016042 lipid catabolic process 5/389 320/18722 0.79782415474353 0.876485437333128 CPT1C/SLC27A2/PLBD1/LRP1/ABHD12 5 GO:0009123 nucleoside monophosphate metabolic process 1/389 76/18722 0.797897354523165 0.876485437333128 TJP2 1 GO:0014823 response to activity 1/389 76/18722 0.797897354523165 0.876485437333128 COL4A2 1 GO:0032720 negative regulation of tumor necrosis factor production 1/389 76/18722 0.797897354523165 0.876485437333128 TRIM27 1 GO:2000379 positive regulation of reactive oxygen species metabolic process 1/389 76/18722 0.797897354523165 0.876485437333128 EGFR 1 GO:0009117 nucleotide metabolic process 8/389 489/18722 0.800284684564456 0.8788431931968 PDK2/TJP2/SLC26A2/HMGCR/ACSF2/TDG/MTHFD2L/COASY 8 GO:0062013 positive regulation of small molecule metabolic process 2/389 143/18722 0.800791396805391 0.878949014381357 PPARG/WDR5 2 GO:0008380 RNA splicing 7/389 434/18722 0.800863058620578 0.878949014381357 SRRM4/RBFOX2/PPIL1/HNRNPLL/ESRP1/WBP4/ECD 7 GO:0006091 generation of precursor metabolites and energy 8/389 490/18722 0.802068374202204 0.879527556939401 AIFM2/COX10/GLDC/CEBPA/GYG1/SLC25A4/IL6ST/COQ9 8 GO:0002200 somatic diversification of immune receptors 1/389 77/18722 0.802113697389758 0.879527556939401 TFRC 1 GO:0055117 regulation of cardiac muscle contraction 1/389 77/18722 0.802113697389758 0.879527556939401 DMD 1 GO:0031644 regulation of nervous system process 2/389 144/18722 0.803926420629814 0.880759253475092 UNC13B/DAG1 2 GO:0051607 defense response to virus 4/389 265/18722 0.803961490216227 0.880759253475092 ATAD3A/POLR3F/ANKRD17/SKP2 4 GO:0140546 defense response to symbiont 4/389 265/18722 0.803961490216227 0.880759253475092 ATAD3A/POLR3F/ANKRD17/SKP2 4 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 1/389 78/18722 0.806242298715335 0.881933312361976 PPARG 1 GO:0034637 cellular carbohydrate biosynthetic process 1/389 78/18722 0.806242298715335 0.881933312361976 GYG1 1 GO:0043537 negative regulation of blood vessel endothelial cell migration 1/389 78/18722 0.806242298715335 0.881933312361976 PPARG 1 GO:1901616 organic hydroxy compound catabolic process 1/389 78/18722 0.806242298715335 0.881933312361976 SYNJ2 1 GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 1/389 78/18722 0.806242298715335 0.881933312361976 TRIM27 1 GO:0007269 neurotransmitter secretion 2/389 145/18722 0.807017605047572 0.882252159954585 UNC13B/SYT1 2 GO:0099643 signal release from synapse 2/389 145/18722 0.807017605047572 0.882252159954585 UNC13B/SYT1 2 GO:0006836 neurotransmitter transport 3/389 208/18722 0.809968192721305 0.885212465943841 UNC13B/SYT1/SLC1A3 3 GO:0001895 retina homeostasis 1/389 79/18722 0.810284979781616 0.885293385639171 SLC2A1 1 GO:0006753 nucleoside phosphate metabolic process 8/389 497/18722 0.814220732860887 0.889018771195707 PDK2/TJP2/SLC26A2/HMGCR/ACSF2/TDG/MTHFD2L/COASY 8 GO:0048145 regulation of fibroblast proliferation 1/389 80/18722 0.814243524161005 0.889018771195707 MED31 1 GO:0009259 ribonucleotide metabolic process 6/389 385/18722 0.814426025381096 0.889018771195707 PDK2/TJP2/SLC26A2/HMGCR/ACSF2/COASY 6 GO:2001056 positive regulation of cysteine-type endopeptidase activity 2/389 148/18722 0.816032746045669 0.890506111558514 PPARG/NLRP2 2 GO:0050727 regulation of inflammatory response 6/389 386/18722 0.816324050824226 0.89055752717797 PPARG/ABHD12/CEBPA/SETD4/IL6ST/EGFR 6 GO:0050863 regulation of T cell activation 5/389 329/18722 0.816845584982185 0.890860002520942 GLI3/TFRC/ABL1/IL6ST/XBP1 5 GO:0001960 negative regulation of cytokine-mediated signaling pathway 1/389 81/18722 0.818119678495377 0.891183532697921 PPARG 1 GO:0048144 fibroblast proliferation 1/389 81/18722 0.818119678495377 0.891183532697921 MED31 1 GO:0051149 positive regulation of muscle cell differentiation 1/389 81/18722 0.818119678495377 0.891183532697921 MMP14 1 GO:2001021 negative regulation of response to DNA damage stimulus 1/389 81/18722 0.818119678495377 0.891183532697921 MAGEF1 1 GO:0045834 positive regulation of lipid metabolic process 2/389 149/18722 0.818953195042346 0.891558896214757 PPARG/PTK2 2 GO:0051592 response to calcium ion 2/389 149/18722 0.818953195042346 0.891558896214757 SYT1/EGFR 2 GO:0019216 regulation of lipid metabolic process 5/389 331/18722 0.82087244265798 0.893381616942301 MBOAT7/PPARG/PDK2/OPA3/PTK2 5 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 1/389 82/18722 0.821915153258818 0.893449944540956 STK3 1 GO:0035082 axoneme assembly 1/389 82/18722 0.821915153258818 0.893449944540956 SPAG16 1 GO:0043242 negative regulation of protein-containing complex disassembly 1/389 82/18722 0.821915153258818 0.893449944540956 LIMA1 1 GO:1905897 regulation of response to endoplasmic reticulum stress 1/389 82/18722 0.821915153258818 0.893449944540956 XBP1 1 GO:0031497 chromatin assembly 2/389 151/18722 0.824669959801383 0.895887691437507 SUV39H1/HELLS 2 GO:0071456 cellular response to hypoxia 2/389 151/18722 0.824669959801383 0.895887691437507 DNMT3A/SUV39H1 2 GO:0031397 negative regulation of protein ubiquitination 1/389 83/18722 0.825631623504651 0.895887691437507 ABL1 1 GO:0051899 membrane depolarization 1/389 83/18722 0.825631623504651 0.895887691437507 ABL1 1 GO:0061053 somite development 1/389 83/18722 0.825631623504651 0.895887691437507 COBL 1 GO:1901292 nucleoside phosphate catabolic process 1/389 83/18722 0.825631623504651 0.895887691437507 TDG 1 GO:0062012 regulation of small molecule metabolic process 5/389 334/18722 0.826779102212407 0.896865968402334 SLC7A11/PPARG/PDK2/CLN3/WDR5 5 GO:0090501 RNA phosphodiester bond hydrolysis 2/389 152/18722 0.827467193483698 0.897345481604237 RCL1/ELAC2 2 GO:0009953 dorsal/ventral pattern formation 1/389 84/18722 0.829270729597075 0.897966256187806 GLI3 1 GO:0015844 monoamine transport 1/389 84/18722 0.829270729597075 0.897966256187806 SYT1 1 GO:0097061 dendritic spine organization 1/389 84/18722 0.829270729597075 0.897966256187806 EPHB3 1 GO:0098586 cellular response to virus 1/389 84/18722 0.829270729597075 0.897966256187806 ANKRD17 1 GO:1900542 regulation of purine nucleotide metabolic process 1/389 84/18722 0.829270729597075 0.897966256187806 PDK2 1 GO:0002709 regulation of T cell mediated immunity 1/389 85/18722 0.832834077927729 0.900221067635574 FZD5 1 GO:0030433 ubiquitin-dependent ERAD pathway 1/389 85/18722 0.832834077927729 0.900221067635574 UBXN8 1 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 1/389 85/18722 0.832834077927729 0.900221067635574 IL6ST 1 GO:0055072 iron ion homeostasis 1/389 85/18722 0.832834077927729 0.900221067635574 TFRC 1 GO:0071277 cellular response to calcium ion 1/389 85/18722 0.832834077927729 0.900221067635574 SYT1 1 GO:2000779 regulation of double-strand break repair 1/389 85/18722 0.832834077927729 0.900221067635574 MAGEF1 1 GO:0019693 ribose phosphate metabolic process 6/389 396/18722 0.834474865213899 0.901678951946435 PDK2/TJP2/SLC26A2/HMGCR/ACSF2/COASY 6 GO:0002263 cell activation involved in immune response 4/389 279/18722 0.834677307861575 0.901678951946435 LRP1/TFRC/ABL1/XBP1 4 GO:0006140 regulation of nucleotide metabolic process 1/389 86/18722 0.836323241617492 0.902627803376472 PDK2 1 GO:0046928 regulation of neurotransmitter secretion 1/389 86/18722 0.836323241617492 0.902627803376472 SYT1 1 GO:0060761 negative regulation of response to cytokine stimulus 1/389 86/18722 0.836323241617492 0.902627803376472 PPARG 1 GO:0071805 potassium ion transmembrane transport 3/389 219/18722 0.836545647220312 0.902627803376472 SLC1A3/TMEM175/ANO6 3 GO:0046631 alpha-beta T cell activation 2/389 156/18722 0.838259118973705 0.904209111770808 GLI3/ABL1 2 GO:0007029 endoplasmic reticulum organization 1/389 87/18722 0.839739761203819 0.905003223732367 EMC1 1 GO:0019646 aerobic electron transport chain 1/389 87/18722 0.839739761203819 0.905003223732367 COQ9 1 GO:1901879 regulation of protein depolymerization 1/389 87/18722 0.839739761203819 0.905003223732367 LIMA1 1 GO:0007260 tyrosine phosphorylation of STAT protein 1/389 88/18722 0.843085145313919 0.908071921134041 IL6ST 1 GO:0070098 chemokine-mediated signaling pathway 1/389 88/18722 0.843085145313919 0.908071921134041 ACKR2 1 GO:0032200 telomere organization 2/389 159/18722 0.845948870037254 0.910349816767738 PCNA/BLM 2 GO:0035966 response to topologically incorrect protein 2/389 159/18722 0.845948870037254 0.910349816767738 UGGT2/XBP1 2 GO:1903169 regulation of calcium ion transmembrane transport 2/389 159/18722 0.845948870037254 0.910349816767738 ABL1/DMD 2 GO:0046330 positive regulation of JNK cascade 1/389 89/18722 0.846360871324056 0.910524512601425 STK3 1 GO:0032984 protein-containing complex disassembly 3/389 224/18722 0.847530570084208 0.911514004452111 CLN3/MTRF1L/LIMA1 3 GO:0035637 multicellular organismal signaling 2/389 160/18722 0.848437521427606 0.912220412926439 GJA1/JAM3 2 GO:0007059 chromosome segregation 5/389 346/18722 0.848846766267913 0.912391440194247 MAP10/CENPE/RACGAP1/SMC2/DYNC1H1 5 GO:0034644 cellular response to UV 1/389 90/18722 0.849568386005264 0.912715902389032 PCNA 1 GO:0008037 cell recognition 3/389 225/18722 0.849649160573283 0.912715902389032 EPHB3/IGLL1/NRP1 3 GO:0036294 cellular response to decreased oxygen levels 2/389 161/18722 0.850889612377991 0.913779274541382 DNMT3A/SUV39H1 2 GO:0006354 DNA-templated transcription, elongation 1/389 91/18722 0.852709106155755 0.914655914750011 EZH2 1 GO:0019935 cyclic-nucleotide-mediated signaling 1/389 91/18722 0.852709106155755 0.914655914750011 RAPGEF2 1 GO:0051952 regulation of amine transport 1/389 91/18722 0.852709106155755 0.914655914750011 SYT1 1 GO:0051983 regulation of chromosome segregation 1/389 91/18722 0.852709106155755 0.914655914750011 CENPE 1 GO:0050657 nucleic acid transport 2/389 163/18722 0.855685870333656 0.916068616641153 NUP58/MYO1C 2 GO:0050658 RNA transport 2/389 163/18722 0.855685870333656 0.916068616641153 NUP58/MYO1C 2 GO:0031058 positive regulation of histone modification 1/389 92/18722 0.855784419220293 0.916068616641153 WDR5 1 GO:0034502 protein localization to chromosome 1/389 92/18722 0.855784419220293 0.916068616641153 EZH2 1 GO:0048525 negative regulation of viral process 1/389 92/18722 0.855784419220293 0.916068616641153 TRIM27 1 GO:0070509 calcium ion import 1/389 92/18722 0.855784419220293 0.916068616641153 TRIM27 1 GO:1903351 cellular response to dopamine 1/389 92/18722 0.855784419220293 0.916068616641153 ABL1 1 GO:0002764 immune response-regulating signaling pathway 7/389 468/18722 0.857484005649233 0.916333487177187 PRKCH/IGLL1/RAB7B/ABL1/ANKRD17/IRAK4/PTK2 7 GO:0002429 immune response-activating cell surface receptor signaling pathway 4/389 291/18722 0.857715828028809 0.916333487177187 PRKCH/IGLL1/ABL1/PTK2 4 GO:0002757 immune response-activating signal transduction 4/389 291/18722 0.857715828028809 0.916333487177187 PRKCH/IGLL1/ABL1/PTK2 4 GO:2001242 regulation of intrinsic apoptotic signaling pathway 2/389 164/18722 0.858030909822582 0.916333487177187 HELLS/XBP1 2 GO:0032088 negative regulation of NF-kappaB transcription factor activity 1/389 93/18722 0.858795683896799 0.916333487177187 NLRP2 1 GO:0045132 meiotic chromosome segregation 1/389 93/18722 0.858795683896799 0.916333487177187 SMC2 1 GO:0051591 response to cAMP 1/389 93/18722 0.858795683896799 0.916333487177187 RAPGEF2 1 GO:0090398 cellular senescence 1/389 93/18722 0.858795683896799 0.916333487177187 ABL1 1 GO:0106027 neuron projection organization 1/389 93/18722 0.858795683896799 0.916333487177187 EPHB3 1 GO:1901019 regulation of calcium ion transmembrane transporter activity 1/389 93/18722 0.858795683896799 0.916333487177187 DMD 1 GO:1903350 response to dopamine 1/389 93/18722 0.858795683896799 0.916333487177187 ABL1 1 GO:0030595 leukocyte chemotaxis 3/389 230/18722 0.859862510177278 0.916935255735828 JAM3/PTK2/ANO6 3 GO:0045333 cellular respiration 3/389 230/18722 0.859862510177278 0.916935255735828 AIFM2/COX10/COQ9 3 GO:0019080 viral gene expression 1/389 94/18722 0.861744230730453 0.91840479528754 TRIM27 1 GO:0030316 osteoclast differentiation 1/389 94/18722 0.861744230730453 0.91840479528754 TFRC 1 GO:0051236 establishment of RNA localization 2/389 166/18722 0.862616971525863 0.919066343895653 NUP58/MYO1C 2 GO:0010948 negative regulation of cell cycle process 4/389 294/18722 0.863030646317703 0.919145905352133 DCUN1D3/FZR1/BLM/EZH2 4 GO:0019221 cytokine-mediated signaling pathway 7/389 472/18722 0.863195702174679 0.919145905352133 PPARG/YAP1/ACKR2/CEBPA/IRAK4/PRLR/IL6ST 7 GO:0006942 regulation of striated muscle contraction 1/389 95/18722 0.864631362695552 0.919332530539556 DMD 1 GO:0042773 ATP synthesis coupled electron transport 1/389 95/18722 0.864631362695552 0.919332530539556 COQ9 1 GO:0042775 mitochondrial ATP synthesis coupled electron transport 1/389 95/18722 0.864631362695552 0.919332530539556 COQ9 1 GO:0042982 amyloid precursor protein metabolic process 1/389 95/18722 0.864631362695552 0.919332530539556 CLN3 1 GO:1901379 regulation of potassium ion transmembrane transport 1/389 95/18722 0.864631362695552 0.919332530539556 ANO6 1 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 3/389 233/18722 0.865694937654696 0.920195114435056 LGR5/RAPGEF2/ADGRG1 3 GO:0002706 regulation of lymphocyte mediated immunity 2/389 168/18722 0.867067193995241 0.920459884630867 FZD5/TFRC 2 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2/389 168/18722 0.867067193995241 0.920459884630867 FZD5/TFRC 2 GO:0002833 positive regulation of response to biotic stimulus 2/389 168/18722 0.867067193995241 0.920459884630867 POLR3F/ANKRD17 2 GO:0002718 regulation of cytokine production involved in immune response 1/389 96/18722 0.867458355765366 0.920459884630867 FZD5 1 GO:0034620 cellular response to unfolded protein 1/389 96/18722 0.867458355765366 0.920459884630867 XBP1 1 GO:0051304 chromosome separation 1/389 96/18722 0.867458355765366 0.920459884630867 CENPE 1 GO:0000075 cell cycle checkpoint signaling 2/389 169/18722 0.86924242378736 0.921816551192935 FZR1/BLM 2 GO:0006937 regulation of muscle contraction 2/389 169/18722 0.86924242378736 0.921816551192935 DOCK5/DMD 2 GO:0070252 actin-mediated cell contraction 1/389 97/18722 0.870226459470256 0.922055751797798 GJA1 1 GO:1990868 response to chemokine 1/389 97/18722 0.870226459470256 0.922055751797798 ACKR2 1 GO:1990869 cellular response to chemokine 1/389 97/18722 0.870226459470256 0.922055751797798 ACKR2 1 GO:0002367 cytokine production involved in immune response 1/389 98/18722 0.872936897444273 0.924122166902544 FZD5 1 GO:0032642 regulation of chemokine production 1/389 98/18722 0.872936897444273 0.924122166902544 LRP1 1 GO:0061337 cardiac conduction 1/389 98/18722 0.872936897444273 0.924122166902544 GJA1 1 GO:0042129 regulation of T cell proliferation 2/389 171/18722 0.873495211256012 0.924248884356566 TFRC/IL6ST 2 GO:0006913 nucleocytoplasmic transport 4/389 301/18722 0.874776217960938 0.924248884356566 RGPD5/CDH1/GLI3/NUP58 4 GO:0051169 nuclear transport 4/389 301/18722 0.874776217960938 0.924248884356566 RGPD5/CDH1/GLI3/NUP58 4 GO:1901136 carbohydrate derivative catabolic process 2/389 172/18722 0.875573596120554 0.924248884356566 TDG/GPC1 2 GO:0000045 autophagosome assembly 1/389 99/18722 0.875590867960498 0.924248884356566 TRAPPC8 1 GO:0002444 myeloid leukocyte mediated immunity 1/389 99/18722 0.875590867960498 0.924248884356566 IRAK4 1 GO:0007631 feeding behavior 1/389 99/18722 0.875590867960498 0.924248884356566 NPW 1 GO:0015837 amine transport 1/389 99/18722 0.875590867960498 0.924248884356566 SYT1 1 GO:0032602 chemokine production 1/389 99/18722 0.875590867960498 0.924248884356566 LRP1 1 GO:0060996 dendritic spine development 1/389 99/18722 0.875590867960498 0.924248884356566 EPHB3 1 GO:0006626 protein targeting to mitochondrion 1/389 100/18722 0.878189544455336 0.925652389777055 FZD5 1 GO:0006641 triglyceride metabolic process 1/389 100/18722 0.878189544455336 0.925652389777055 MBOAT7 1 GO:0006664 glycolipid metabolic process 1/389 100/18722 0.878189544455336 0.925652389777055 PIGV 1 GO:0006910 phagocytosis, recognition 1/389 100/18722 0.878189544455336 0.925652389777055 IGLL1 1 GO:0051588 regulation of neurotransmitter transport 1/389 100/18722 0.878189544455336 0.925652389777055 SYT1 1 GO:0050851 antigen receptor-mediated signaling pathway 3/389 240/18722 0.878481045644131 0.925692104439221 PRKCH/IGLL1/ABL1 3 GO:0006813 potassium ion transport 3/389 241/18722 0.880216852264299 0.926994855793702 SLC1A3/TMEM175/ANO6 3 GO:0006476 protein deacetylation 1/389 101/18722 0.880734076042001 0.926994855793702 SPRED2 1 GO:0098869 cellular oxidant detoxification 1/389 101/18722 0.880734076042001 0.926994855793702 TXNRD3 1 GO:1903509 liposaccharide metabolic process 1/389 101/18722 0.880734076042001 0.926994855793702 PIGV 1 GO:0042110 T cell activation 7/389 487/18722 0.882972635151899 0.929080968989015 FZD5/GLI3/TFRC/ABL1/AZI2/IL6ST/XBP1 7 GO:1990542 mitochondrial transmembrane transport 1/389 102/18722 0.883225588013413 0.929080968989015 SLC25A4 1 GO:0050900 leukocyte migration 5/389 369/18722 0.88465294365794 0.929769982721569 JAM3/MMP14/IRAK4/PTK2/ANO6 5 GO:0006333 chromatin assembly or disassembly 2/389 177/18722 0.885501691747228 0.929769982721569 SUV39H1/HELLS 2 GO:0071453 cellular response to oxygen levels 2/389 177/18722 0.885501691747228 0.929769982721569 DNMT3A/SUV39H1 2 GO:0002027 regulation of heart rate 1/389 103/18722 0.885665182334722 0.929769982721569 DMD 1 GO:0009135 purine nucleoside diphosphate metabolic process 1/389 103/18722 0.885665182334722 0.929769982721569 TJP2 1 GO:0009179 purine ribonucleoside diphosphate metabolic process 1/389 103/18722 0.885665182334722 0.929769982721569 TJP2 1 GO:0030593 neutrophil chemotaxis 1/389 103/18722 0.885665182334722 0.929769982721569 JAM3 1 GO:0070663 regulation of leukocyte proliferation 3/389 245/18722 0.886941942714616 0.930842378440346 TFRC/PTK2/IL6ST 3 GO:0035725 sodium ion transmembrane transport 2/389 178/18722 0.887397339571963 0.931052387059537 DMD/ANO6 2 GO:0032006 regulation of TOR signaling 1/389 104/18722 0.888053938125677 0.93120549521114 SLC38A9 1 GO:0046634 regulation of alpha-beta T cell activation 1/389 104/18722 0.888053938125677 0.93120549521114 GLI3 1 GO:0032409 regulation of transporter activity 4/389 310/18722 0.888594035469115 0.931504009012895 PPARG/GJA1/TCAF1/DMD 4 GO:0006941 striated muscle contraction 2/389 179/18722 0.889263912951435 0.931670637901145 GJA1/DMD 2 GO:0010950 positive regulation of endopeptidase activity 2/389 179/18722 0.889263912951435 0.931670637901145 PPARG/NLRP2 2 GO:0042391 regulation of membrane potential 6/389 434/18722 0.890693142966779 0.932900026536428 GABRE/UNC13B/GJA1/ABL1/CLN3/DMD 6 GO:0006090 pyruvate metabolic process 1/389 106/18722 0.892683139193269 0.933911476947175 PDK2 1 GO:0009185 ribonucleoside diphosphate metabolic process 1/389 106/18722 0.892683139193269 0.933911476947175 TJP2 1 GO:0042116 macrophage activation 1/389 106/18722 0.892683139193269 0.933911476947175 CEBPA 1 GO:0099565 chemical synaptic transmission, postsynaptic 1/389 106/18722 0.892683139193269 0.933911476947175 UNC13B 1 GO:0071868 cellular response to monoamine stimulus 1/389 107/18722 0.894925632685631 0.935720694496702 ABL1 1 GO:0071870 cellular response to catecholamine stimulus 1/389 107/18722 0.894925632685631 0.935720694496702 ABL1 1 GO:0002768 immune response-regulating cell surface receptor signaling pathway 4/389 315/18722 0.895681601519498 0.93597444147324 PRKCH/IGLL1/ABL1/PTK2 4 GO:0018105 peptidyl-serine phosphorylation 4/389 315/18722 0.895681601519498 0.93597444147324 PRKCH/TFRC/DMD/EGFR 4 GO:0003015 heart process 3/389 251/18722 0.896399034126697 0.936187651048128 GJA1/YAP1/DMD 3 GO:0006302 double-strand break repair 3/389 251/18722 0.896399034126697 0.936187651048128 MAGEF1/BLM/MCM5 3 GO:0006958 complement activation, classical pathway 1/389 108/18722 0.897121384976004 0.936673830806609 IGLL1 1 GO:0051346 negative regulation of hydrolase activity 5/389 379/18722 0.897807351652162 0.936954893975313 LRP1/ABL1/SERPINE2/ITIH5/SPINT1 5 GO:0010951 negative regulation of endopeptidase activity 3/389 252/18722 0.897904402095892 0.936954893975313 SERPINE2/ITIH5/SPINT1 3 GO:0002456 T cell mediated immunity 1/389 109/18722 0.899271367851492 0.937844632128794 FZD5 1 GO:0043266 regulation of potassium ion transport 1/389 109/18722 0.899271367851492 0.937844632128794 ANO6 1 GO:0006939 smooth muscle contraction 1/389 110/18722 0.901376532946091 0.938697948502111 DOCK5 1 GO:0007088 regulation of mitotic nuclear division 1/389 110/18722 0.901376532946091 0.938697948502111 LRP5 1 GO:0030317 flagellated sperm motility 1/389 110/18722 0.901376532946091 0.938697948502111 SPAG16 1 GO:0097722 sperm motility 1/389 110/18722 0.901376532946091 0.938697948502111 SPAG16 1 GO:1904659 glucose transmembrane transport 1/389 110/18722 0.901376532946091 0.938697948502111 SLC2A1 1 GO:0006338 chromatin remodeling 3/389 255/18722 0.902303326314611 0.938929128734214 SMARCA1/KDM5B/HELLS 3 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 4/389 320/18722 0.902370879137214 0.938929128734214 SRRM4/RBFOX2/PPIL1/WBP4 4 GO:0000398 mRNA splicing, via spliceosome 4/389 320/18722 0.902370879137214 0.938929128734214 SRRM4/RBFOX2/PPIL1/WBP4 4 GO:0006805 xenobiotic metabolic process 1/389 111/18722 0.903437812157566 0.938967711866242 GSTA4 1 GO:0015718 monocarboxylic acid transport 1/389 111/18722 0.903437812157566 0.938967711866242 SLC16A1 1 GO:0071867 response to monoamine 1/389 111/18722 0.903437812157566 0.938967711866242 ABL1 1 GO:0071869 response to catecholamine 1/389 111/18722 0.903437812157566 0.938967711866242 ABL1 1 GO:1901222 regulation of NIK/NF-kappaB signaling 1/389 112/18722 0.905456118055729 0.940797282777562 EGFR 1 GO:0009060 aerobic respiration 2/389 189/18722 0.906413714447368 0.941524014978511 COX10/COQ9 2 GO:0071347 cellular response to interleukin-1 1/389 113/18722 0.907432344282291 0.942060975749147 IRAK4 1 GO:0000375 RNA splicing, via transesterification reactions 4/389 324/18722 0.907447273870785 0.942060975749147 SRRM4/RBFOX2/PPIL1/WBP4 4 GO:0008645 hexose transmembrane transport 1/389 114/18722 0.909367365942465 0.943517150381841 SLC2A1 1 GO:0051261 protein depolymerization 1/389 114/18722 0.909367365942465 0.943517150381841 LIMA1 1 GO:0051321 meiotic cell cycle 3/389 261/18722 0.910592440225528 0.944519519198663 ASPM/FZR1/SMC2 3 GO:0002831 regulation of response to biotic stimulus 4/389 327/18722 0.911099930394029 0.944777209595401 PPARG/POLR3F/TRIB1/ANKRD17 4 GO:0031330 negative regulation of cellular catabolic process 3/389 262/18722 0.911910382025733 0.945256443033145 MET/LZTS1/LRIG2 3 GO:0007006 mitochondrial membrane organization 1/389 116/18722 0.91311720559522 0.945256443033145 SLC25A4 1 GO:0015749 monosaccharide transmembrane transport 1/389 116/18722 0.91311720559522 0.945256443033145 SLC2A1 1 GO:0018107 peptidyl-threonine phosphorylation 1/389 116/18722 0.91311720559522 0.945256443033145 SPRED2 1 GO:0033559 unsaturated fatty acid metabolic process 1/389 116/18722 0.91311720559522 0.945256443033145 ABHD12 1 GO:1990748 cellular detoxification 1/389 116/18722 0.91311720559522 0.945256443033145 TXNRD3 1 GO:0050777 negative regulation of immune response 2/389 194/18722 0.914027641824485 0.945930422739472 PPARG/TRIM27 2 GO:1903828 negative regulation of cellular protein localization 1/389 117/18722 0.914933684528009 0.946599474460609 POLR1A 1 GO:0034219 carbohydrate transmembrane transport 1/389 118/18722 0.91671228150294 0.947835037897872 SLC2A1 1 GO:0051101 regulation of DNA binding 1/389 118/18722 0.91671228150294 0.947835037897872 PPARG 1 GO:0071674 mononuclear cell migration 2/389 196/18722 0.91690759904132 0.947835037897872 PTK2/ANO6 2 GO:0002761 regulation of myeloid leukocyte differentiation 1/389 120/18722 0.920158965306971 0.950657151975786 TRIB1 1 GO:0072655 establishment of protein localization to mitochondrion 1/389 120/18722 0.920158965306971 0.950657151975786 FZD5 1 GO:1903037 regulation of leukocyte cell-cell adhesion 4/389 336/18722 0.921301546923398 0.951568037844699 GLI3/TFRC/IL6ST/XBP1 4 GO:0002455 humoral immune response mediated by circulating immunoglobulin 1/389 121/18722 0.921828579461126 0.951624650361554 IGLL1 1 GO:0022613 ribonucleoprotein complex biogenesis 6/389 463/18722 0.921878225864374 0.951624650361554 RCL1/MRM1/SUV39H1/RPF1/WDR36/NSUN4 6 GO:0018209 peptidyl-serine modification 4/389 338/18722 0.923421304739174 0.952174572005943 PRKCH/TFRC/DMD/EGFR 4 GO:0050868 negative regulation of T cell activation 1/389 122/18722 0.923463366977368 0.952174572005943 GLI3 1 GO:0051928 positive regulation of calcium ion transport 1/389 122/18722 0.923463366977368 0.952174572005943 ABL1 1 GO:0006403 RNA localization 2/389 201/18722 0.923716379423369 0.952174572005943 NUP58/MYO1C 2 GO:0065004 protein-DNA complex assembly 2/389 201/18722 0.923716379423369 0.952174572005943 CENPE/HELLS 2 GO:0002697 regulation of immune effector process 4/389 339/18722 0.924461882530115 0.952218063611159 FZD5/TFRC/ANKRD17/XBP1 4 GO:0017157 regulation of exocytosis 2/389 202/18722 0.925013614724403 0.952218063611159 SYT1/HGS 2 GO:0006690 icosanoid metabolic process 1/389 123/18722 0.925064052474455 0.952218063611159 ABHD12 1 GO:0050852 T cell receptor signaling pathway 1/389 123/18722 0.925064052474455 0.952218063611159 ABL1 1 GO:0071482 cellular response to light stimulus 1/389 123/18722 0.925064052474455 0.952218063611159 PCNA 1 GO:0001909 leukocyte mediated cytotoxicity 1/389 124/18722 0.926631345532546 0.953024398521487 RNF19B 1 GO:0009132 nucleoside diphosphate metabolic process 1/389 124/18722 0.926631345532546 0.953024398521487 TJP2 1 GO:0097237 cellular response to toxic substance 1/389 124/18722 0.926631345532546 0.953024398521487 TXNRD3 1 GO:0002366 leukocyte activation involved in immune response 3/389 275/18722 0.927509425582472 0.953658549506421 TFRC/ABL1/XBP1 3 GO:0060294 cilium movement involved in cell motility 1/389 125/18722 0.928165941004523 0.95379576975021 SPAG16 1 GO:0070585 protein localization to mitochondrion 1/389 125/18722 0.928165941004523 0.95379576975021 FZD5 1 GO:0031929 TOR signaling 1/389 126/18722 0.929668519320878 0.954801771321667 SLC38A9 1 GO:2001235 positive regulation of apoptotic signaling pathway 1/389 126/18722 0.929668519320878 0.954801771321667 STK3 1 GO:0008016 regulation of heart contraction 2/389 206/18722 0.929997663481841 0.954870911801315 GJA1/DMD 2 GO:0022898 regulation of transmembrane transporter activity 3/389 278/18722 0.930730162749045 0.955023696953999 GJA1/TCAF1/DMD 3 GO:0008033 tRNA processing 1/389 127/18722 0.9311397467883 0.955023696953999 ELAC2 1 GO:0035270 endocrine system development 1/389 127/18722 0.9311397467883 0.955023696953999 CDH1 1 GO:0016064 immunoglobulin mediated immune response 2/389 207/18722 0.931193931003132 0.955023696953999 IGLL1/TFRC 2 GO:0006936 muscle contraction 4/389 347/18722 0.932340003553653 0.955930276345283 GJA1/DOCK5/MYOF/DMD 4 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 2/389 209/18722 0.933528793846439 0.956880132422137 PPARG/NLRP2 2 GO:0019724 B cell mediated immunity 2/389 210/18722 0.934667952998201 0.957509557467539 IGLL1/TFRC 2 GO:0050866 negative regulation of cell activation 2/389 210/18722 0.934667952998201 0.957509557467539 GLI3/SERPINE2 2 GO:0002449 lymphocyte mediated immunity 4/389 350/18722 0.935097846663874 0.957680945460025 IGLL1/FZD5/TFRC/RNF19B 4 GO:0006956 complement activation 1/389 130/18722 0.935371781405692 0.957692556649792 IGLL1 1 GO:0045089 positive regulation of innate immune response 1/389 131/18722 0.936723996177271 0.958538836716752 POLR3F 1 GO:0046683 response to organophosphorus 1/389 131/18722 0.936723996177271 0.958538836716752 RAPGEF2 1 GO:0035264 multicellular organism growth 1/389 132/18722 0.938047989802522 0.959624409203309 ZFX 1 GO:0072330 monocarboxylic acid biosynthetic process 2/389 214/18722 0.939042527880614 0.96037243387005 SLC27A2/XBP1 2 GO:0008277 regulation of G protein-coupled receptor signaling pathway 1/389 134/18722 0.940613651405767 0.9617095561191 MET 1 GO:0002377 immunoglobulin production 2/389 216/18722 0.94112432498024 0.961709926149032 TFRC/XBP1 2 GO:0001818 negative regulation of cytokine production 4/389 357/18722 0.941141411139538 0.961709926149032 NDRG2/TRIM27/EZH2/CHID1 4 GO:1903305 regulation of regulated secretory pathway 1/389 136/18722 0.943073321315992 0.963210968130071 SYT1 1 GO:0045088 regulation of innate immune response 2/389 218/18722 0.943138570658756 0.963210968130071 PPARG/POLR3F 2 GO:0006986 response to unfolded protein 1/389 137/18722 0.944264781447708 0.964091169636 XBP1 1 GO:0031503 protein-containing complex localization 2/389 220/18722 0.945087281545655 0.964472222916405 DAG1/ARL3 2 GO:0001539 cilium or flagellum-dependent cell motility 1/389 138/18722 0.945431367405031 0.964472222916405 SPAG16 1 GO:0060285 cilium-dependent cell motility 1/389 138/18722 0.945431367405031 0.964472222916405 SPAG16 1 GO:0052548 regulation of endopeptidase activity 5/389 432/18722 0.947916519288776 0.966737009464812 PPARG/SERPINE2/ITIH5/SPINT1/NLRP2 5 GO:0006119 oxidative phosphorylation 1/389 141/18722 0.948787006544961 0.966918331422193 COQ9 1 GO:1903038 negative regulation of leukocyte cell-cell adhesion 1/389 141/18722 0.948787006544961 0.966918331422193 GLI3 1 GO:0009615 response to virus 4/389 367/18722 0.948889692393756 0.966918331422193 ATAD3A/POLR3F/ANKRD17/SKP2 4 GO:0050670 regulation of lymphocyte proliferation 2/389 225/18722 0.949685119348025 0.967365649289011 TFRC/IL6ST 2 GO:0046467 membrane lipid biosynthetic process 1/389 142/18722 0.949859169208651 0.967365649289011 PIGV 1 GO:0002703 regulation of leukocyte mediated immunity 2/389 226/18722 0.950559610198573 0.967624138504298 FZD5/TFRC 2 GO:0038061 NIK/NF-kappaB signaling 1/389 143/18722 0.950908942253744 0.967624138504298 EGFR 1 GO:0070555 response to interleukin-1 1/389 143/18722 0.950908942253744 0.967624138504298 IRAK4 1 GO:0032944 regulation of mononuclear cell proliferation 2/389 227/18722 0.951419608994143 0.96787372775499 TFRC/IL6ST 2 GO:0007159 leukocyte cell-cell adhesion 4/389 371/18722 0.951718929892413 0.967908236842619 GLI3/TFRC/IL6ST/XBP1 4 GO:0002443 leukocyte mediated immunity 5/389 440/18722 0.9531581011374 0.969101643392277 IGLL1/FZD5/TFRC/IRAK4/RNF19B 5 GO:0045055 regulated exocytosis 2/389 230/18722 0.95391486452139 0.969600755548916 UNC13B/SYT1 2 GO:0002253 activation of immune response 4/389 375/18722 0.954403911563254 0.969827546801668 PRKCH/IGLL1/ABL1/PTK2 4 GO:0014074 response to purine-containing compound 1/389 148/18722 0.955837951366014 0.970743806358077 RAPGEF2 1 GO:1903900 regulation of viral life cycle 1/389 148/18722 0.955837951366014 0.970743806358077 TRIM27 1 GO:0002440 production of molecular mediator of immune response 3/389 308/18722 0.956420100760355 0.971064617893378 FZD5/TFRC/XBP1 3 GO:0001959 regulation of cytokine-mediated signaling pathway 1/389 150/18722 0.957668423772539 0.971928528873067 PPARG 1 GO:2000116 regulation of cysteine-type endopeptidase activity 2/389 235/18722 0.957803984855992 0.971928528873067 PPARG/NLRP2 2 GO:0008643 carbohydrate transport 1/389 152/18722 0.959423211899115 0.97275964798334 SLC2A1 1 GO:0016573 histone acetylation 1/389 152/18722 0.959423211899115 0.97275964798334 WDR5 1 GO:0031056 regulation of histone modification 1/389 152/18722 0.959423211899115 0.97275964798334 WDR5 1 GO:0120254 olefinic compound metabolic process 1/389 153/18722 0.960273204929339 0.973350855580127 ABHD12 1 GO:0060047 heart contraction 2/389 241/18722 0.962057320309017 0.97461751310194 GJA1/DMD 2 GO:0071824 protein-DNA complex subunit organization 2/389 241/18722 0.962057320309017 0.97461751310194 CENPE/HELLS 2 GO:0043543 protein acylation 2/389 243/18722 0.963381494668822 0.974994924158352 ZDHHC13/WDR5 2 GO:0051250 negative regulation of lymphocyte activation 1/389 157/18722 0.963499234073677 0.974994924158352 GLI3 1 GO:1902600 proton transmembrane transport 1/389 157/18722 0.963499234073677 0.974994924158352 SLC25A4 1 GO:2000377 regulation of reactive oxygen species metabolic process 1/389 157/18722 0.963499234073677 0.974994924158352 EGFR 1 GO:0018393 internal peptidyl-lysine acetylation 1/389 158/18722 0.964264049476065 0.975498193741806 WDR5 1 GO:0016570 histone modification 5/389 463/18722 0.965667828060103 0.976455745444098 KDM5B/SUV39H1/EZH2/SETD4/WDR5 5 GO:0006475 internal protein amino acid acetylation 1/389 160/18722 0.965746058079754 0.976455745444098 WDR5 1 GO:0060759 regulation of response to cytokine stimulus 1/389 162/18722 0.967166757623289 0.977621165480081 PPARG 1 GO:0006633 fatty acid biosynthetic process 1/389 163/18722 0.967854911248533 0.97804568061053 XBP1 1 GO:0050792 regulation of viral process 1/389 164/18722 0.968528678128447 0.978455426353033 TRIM27 1 GO:0006839 mitochondrial transport 2/389 254/18722 0.969907881987841 0.979577415012367 FZD5/SLC25A4 2 GO:0018394 peptidyl-lysine acetylation 1/389 169/18722 0.971691996139697 0.98110761625733 WDR5 1 GO:0003341 cilium movement 1/389 175/18722 0.975072092934663 0.984230896104216 SPAG16 1 GO:0016311 dephosphorylation 4/389 417/18722 0.975376444853648 0.984230896104216 SYNJ2/PPP4R1/INPP4A/CAMK2G 4 GO:0050728 negative regulation of inflammatory response 1/389 176/18722 0.975594924435629 0.984230896104216 PPARG 1 GO:0032412 regulation of ion transmembrane transporter activity 2/389 267/18722 0.976183236977878 0.984552064507279 TCAF1/DMD 2 GO:0007626 locomotory behavior 1/389 179/18722 0.97709869842154 0.985202917650914 ABHD12 1 GO:0042742 defense response to bacterium 3/389 350/18722 0.977764784645897 0.98560203692747 IGLL1/ANKRD17/SHC1 3 GO:0006887 exocytosis 3/389 352/18722 0.978479419806732 0.986049860192084 UNC13B/SYT1/HGS 3 GO:2001257 regulation of cation channel activity 1/389 184/18722 0.979402390968827 0.986707325929092 DMD 1 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3/389 356/18722 0.97984371198035 0.98675965377829 IGLL1/FZD5/TFRC 3 GO:1904062 regulation of cation transmembrane transport 3/389 357/18722 0.980171697580696 0.98675965377829 ABL1/DMD/ANO6 3 GO:0002695 negative regulation of leukocyte activation 1/389 187/18722 0.980672095443415 0.98675965377829 GLI3 1 GO:0033044 regulation of chromosome organization 1/389 187/18722 0.980672095443415 0.98675965377829 CENPE 1 GO:0002683 negative regulation of immune system process 4/389 434/18722 0.980951840816672 0.98675965377829 PPARG/GLI3/TRIB1/TRIM27 4 GO:0001906 cell killing 1/389 188/18722 0.981077736386092 0.98675965377829 RNF19B 1 GO:0006470 protein dephosphorylation 2/389 281/18722 0.981525446531585 0.986937773228754 PPP4R1/CAMK2G 2 GO:1903311 regulation of mRNA metabolic process 2/389 288/18722 0.983741454180856 0.988893352645419 SRRM4/RBFOX2 2 GO:0006473 protein acetylation 1/389 201/18722 0.985639304708 0.99052811911548 WDR5 1 GO:0006643 membrane lipid metabolic process 1/389 203/18722 0.986236226360343 0.990854963508587 PIGV 1 GO:0002274 myeloid leukocyte activation 1/389 223/18722 0.990999900750266 0.99536674140353 CEBPA 1 GO:0071356 cellular response to tumor necrosis factor 1/389 229/18722 0.992077524212115 0.995983551091003 CEBPA 1 GO:0034765 regulation of ion transmembrane transport 4/389 491/18722 0.992160197727889 0.995983551091003 ABL1/TCAF1/DMD/ANO6 4 GO:0072593 reactive oxygen species metabolic process 1/389 239/18722 0.993595135913196 0.997149548892522 EGFR 1 GO:0017148 negative regulation of translation 1/389 245/18722 0.994362649026298 0.997645276753483 SHMT1 1 GO:0034612 response to tumor necrosis factor 1/389 253/18722 0.995245184816261 0.998256102592107 CEBPA 1 GO:0031348 negative regulation of defense response 1/389 258/18722 0.995725318073795 0.998433714539828 PPARG 1 GO:0044270 cellular nitrogen compound catabolic process 3/389 451/18722 0.995969798052069 0.998433714539828 MPST/TDG/ELAC2 3 GO:0034249 negative regulation of cellular amide metabolic process 1/389 273/18722 0.996894451313148 0.998851668670557 SHMT1 1 GO:0046034 ATP metabolic process 1/389 277/18722 0.997148226952884 0.998851668670557 COQ9 1 GO:0006401 RNA catabolic process 1/389 278/18722 0.99720837006567 0.998851668670557 ELAC2 1 GO:0034655 nucleobase-containing compound catabolic process 2/389 407/18722 0.998262046801171 0.999632532862128 TDG/ELAC2 2 GO:0006959 humoral immune response 1/389 317/18722 0.998785397466047 0.99968621472491 IGLL1 1 GO:0046700 heterocycle catabolic process 2/389 445/18722 0.999165946683508 0.99968621472491 TDG/ELAC2 2 GO:0019439 aromatic compound catabolic process 2/389 467/18722 0.999456689004498 0.99968621472491 TDG/ELAC2 2 GO:0006417 regulation of translation 2/389 468/18722 0.999467202730677 0.99968621472491 SHMT1/CYFIP1 2 GO:1901361 organic cyclic compound catabolic process 2/389 495/18722 0.99968621472491 0.99968621472491 TDG/ELAC2 2