ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	geneName	Count
hsa03010	Ribosome	47/936	91/5868	1.965819271969e-15	4.08890408569553e-13	6227/6235/6193/6218/6228/6201/3921/6232/6222/6168/6188/6141/6217/6175/6208/6125/6157/6167/6206/9349/6192/6130/6176/6147/6223/25873/6158/23521/11224/6122/6144/6233/6210/4736/6160/6187/6203/6181/9045/6194/6202/6129/6138/6224/6191/6230/6132	RPS21/RPS29/RPS5/RPS17/RPS23/RPS7/RPSA/RPS27/RPS18/RPL37A/RPS3/RPL18/RPS16/RPLP0/RPS14/RPL5/RPL27A/RPL37/RPS12/RPL23/RPS4Y1/RPL7A/RPLP1/RPL23A/RPS19/RPL36/RPL28/RPL13A/RPL35/RPL3/RPL21/RPS27A/RPS15A/RPL10A/RPL31/RPS2/RPS9/RPLP2/RPL14/RPS6/RPS8/RPL7/RPL15/RPS20/RPS4X/RPS25/RPL8	47
hsa05140	Leishmaniasis	39/936	72/5868	6.63811641997512e-14	6.90364107677413e-12	3113/3115/3122/3123/2214/3689/3108/4688/2212/1535/653361/2209/3119/3109/3117/7040/3118/7097/2353/3717/3684/3127/7124/7099/3553/3676/6772/718/3716/3460/4792/5777/3688/4689/5579/4615/3725/3459/1432	HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/FCGR3A/ITGB2/HLA-DMA/NCF2/FCGR2A/CYBA/NCF1/FCGR1A/HLA-DQB1/HLA-DMB/HLA-DQA1/TGFB1/HLA-DQA2/TLR2/FOS/JAK2/ITGAM/HLA-DRB5/TNF/TLR4/IL1B/ITGA4/STAT1/C3/JAK1/IFNGR2/NFKBIA/PTPN6/ITGB1/NCF4/PRKCB/MYD88/JUN/IFNGR1/MAPK14	39
hsa04145	Phagosome	61/936	153/5868	4.9246934947533e-13	3.41445415636229e-11	3106/3105/3113/1520/3115/3122/3123/2214/3689/1536/929/3108/11151/4688/3107/2212/1535/3134/653361/2209/3119/3109/64581/3117/4481/3118/3133/7097/7846/60/3684/3678/1514/10376/203068/3127/6891/7099/81035/948/6890/718/4973/10333/3688/10383/9296/811/8685/4689/84790/245973/3693/3685/525/1783/10312/526/7037/8992/8411	HLA-B/HLA-A/HLA-DPA1/CTSS/HLA-DPB1/HLA-DRA/HLA-DRB1/FCGR3A/ITGB2/CYBB/CD14/HLA-DMA/CORO1A/NCF2/HLA-C/FCGR2A/CYBA/HLA-F/NCF1/FCGR1A/HLA-DQB1/HLA-DMB/CLEC7A/HLA-DQA1/MSR1/HLA-DQA2/HLA-E/TLR2/TUBA1A/ACTB/ITGAM/ITGA5/CTSL/TUBA1B/TUBB/HLA-DRB5/TAP2/TLR4/COLEC12/CD36/TAP1/C3/OLR1/TLR6/ITGB1/TUBB4B/ATP6V1F/CALR/MARCO/NCF4/TUBA1C/ATP6V1C2/ITGB5/ITGAV/ATP6V1B1/DYNC1LI2/TCIRG1/ATP6V1B2/TFRC/ATP6V0E1/EEA1	61
hsa03030	DNA replication	24/936	36/5868	1.02443656652567e-11	5.32707014593346e-10	5111/4176/4172/4174/6119/4175/2237/5983/4173/5984/5982/3978/6118/4171/10535/5981/10714/5557/54107/6117/5422/57804/5425/5427	PCNA/MCM7/MCM3/MCM5/RPA3/MCM6/FEN1/RFC3/MCM4/RFC4/RFC2/LIG1/RPA2/MCM2/RNASEH2A/RFC1/POLD3/PRIM1/POLE3/RPA1/POLA1/POLD4/POLD2/POLE2	24
hsa04612	Antigen processing and presentation	37/936	76/5868	2.0409220683061e-11	8.49023580415336e-10	3106/3105/3113/1520/3115/3122/3123/3108/972/3107/10437/3134/3119/3109/3117/3118/567/3133/1508/1514/920/3127/6891/7124/6890/3320/3326/4261/2923/811/5721/3309/3312/3310/6892/4801/3303	HLA-B/HLA-A/HLA-DPA1/CTSS/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/CD74/HLA-C/IFI30/HLA-F/HLA-DQB1/HLA-DMB/HLA-DQA1/HLA-DQA2/B2M/HLA-E/CTSB/CTSL/CD4/HLA-DRB5/TAP2/TNF/TAP1/HSP90AA1/HSP90AB1/CIITA/PDIA3/CALR/PSME2/HSPA5/HSPA8/HSPA6/TAPBP/NFYB/HSPA1A	37
hsa05150	Staphylococcus aureus infection	27/936	55/5868	8.80424238158677e-09	3.05213735895008e-07	3113/3115/3122/3123/2214/3689/3108/2212/2357/2209/3119/3109/3117/728/2359/3118/719/1675/3683/3684/3127/5724/718/6404/712/3383/3858	HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/FCGR3A/ITGB2/HLA-DMA/FCGR2A/FPR1/FCGR1A/HLA-DQB1/HLA-DMB/HLA-DQA1/C5AR1/FPR3/HLA-DQA2/C3AR1/CFD/ITGAL/ITGAM/HLA-DRB5/PTAFR/C3/SELPLG/C1QA/ICAM1/KRT10	27
hsa05323	Rheumatoid arthritis	36/936	91/5868	4.17118946425158e-08	1.2394391550919e-06	3113/3115/3122/414062/3123/3689/3108/6348/10673/3119/3109/3117/7040/942/3118/7097/3683/2353/7422/1514/3127/7124/7099/3553/9296/3383/2321/3576/245973/54/3725/525/10312/526/3606/8992	HLA-DPA1/HLA-DPB1/HLA-DRA/CCL3L3/HLA-DRB1/ITGB2/HLA-DMA/CCL3/TNFSF13B/HLA-DQB1/HLA-DMB/HLA-DQA1/TGFB1/CD86/HLA-DQA2/TLR2/ITGAL/FOS/VEGFA/CTSL/HLA-DRB5/TNF/TLR4/IL1B/ATP6V1F/ICAM1/FLT1/CXCL8/ATP6V1C2/ACP5/JUN/ATP6V1B1/TCIRG1/ATP6V1B2/IL18/ATP6V0E1	36
hsa04110	Cell cycle	44/936	124/5868	6.23675588608068e-08	1.62155653038098e-06	7040/5111/4176/4172/4174/23594/5591/4175/983/9126/7029/4616/4085/990/595/4173/898/51529/7465/1028/1111/4171/896/890/9088/5885/9134/3066/1019/9184/8318/1021/1029/10926/7027/7531/10274/5933/7272/1026/1017/6502/1869/701	TGFB1/PCNA/MCM7/MCM3/MCM5/ORC6/PRKDC/MCM6/CDK1/SMC3/TFDP2/GADD45B/MAD2L1/CDC6/CCND1/MCM4/CCNE1/ANAPC11/WEE1/CDKN1C/CHEK1/MCM2/CCND3/CCNA2/PKMYT1/RAD21/CCNE2/HDAC2/CDK4/BUB3/CDC45/CDK6/CDKN2A/DBF4/TFDP1/YWHAE/STAG1/RBL1/TTK/CDKN1A/CDK2/SKP2/E2F1/BUB1B	44
hsa03430	Mismatch repair	15/936	23/5868	1.37304609962513e-07	3.1732620969114e-06	5111/6119/5983/5984/5982/4436/3978/6118/2956/5981/10714/6117/57804/5425/9156	PCNA/RPA3/RFC3/RFC4/RFC2/MSH2/LIG1/RPA2/MSH6/RFC1/POLD3/RPA1/POLD4/POLD2/EXO1	15
hsa04380	Osteoclast differentiation	44/936	128/5868	1.79779067486805e-07	3.73940460372555e-06	7305/2214/1536/4688/2212/1535/653361/2209/1436/6688/7040/10288/10859/11025/11006/2353/3726/126014/7124/3553/6772/3937/9021/11027/695/3716/3460/4792/6850/10326/79168/54209/4689/23533/2354/6773/140885/2885/54/3725/2274/3459/1432/5468	TYROBP/FCGR3A/CYBB/NCF2/FCGR2A/CYBA/NCF1/FCGR1A/CSF1R/SPI1/TGFB1/LILRB2/LILRB1/LILRB3/LILRB4/FOS/JUNB/OSCAR/TNF/IL1B/STAT1/LCP2/SOCS3/LILRA2/BTK/JAK1/IFNGR2/NFKBIA/SYK/SIRPB1/LILRA6/TREM2/NCF4/PIK3R5/FOSB/STAT2/SIRPA/GRB2/ACP5/JUN/FHL2/IFNGR1/MAPK14/PPARG	44
hsa04514	Cell adhesion molecules (CAMs)	44/936	133/5868	6.16765909464413e-07	1.16624826516907e-05	3106/3105/3113/3115/3122/5788/3123/3689/3108/3107/1462/3134/3119/3109/5175/3117/942/3118/3133/3683/3684/3655/920/999/3127/3676/23705/6404/1364/3688/214/1366/3384/6693/3383/6614/26047/9019/3685/83700/5792/3385/6402/3696	HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/ITGB2/HLA-DMA/HLA-C/VCAN/HLA-F/HLA-DQB1/HLA-DMB/PECAM1/HLA-DQA1/CD86/HLA-DQA2/HLA-E/ITGAL/ITGAM/ITGA6/CD4/CDH1/HLA-DRB5/ITGA4/CADM1/SELPLG/CLDN4/ITGB1/ALCAM/CLDN7/ICAM2/SPN/ICAM1/SIGLEC1/CNTNAP2/MPZL1/ITGAV/JAM3/PTPRF/ICAM3/SELL/ITGB8	44
hsa03050	Proteasome	20/936	44/5868	3.53960709391003e-06	5.91682943057615e-05	5698/5696/5713/5721/5702/5684/5707/5690/5717/5693/5700/5694/5689/10213/5708/5701/5699/5718/5695/5682	PSMB9/PSMB8/PSMD7/PSME2/PSMC3/PSMA3/PSMD1/PSMB2/PSMD11/PSMB5/PSMC1/PSMB6/PSMB1/PSMD14/PSMD2/PSMC2/PSMB10/PSMD12/PSMB7/PSMA1	20
hsa05416	Viral myocarditis	27/936	70/5868	3.69801839411009e-06	5.91682943057615e-05	3106/3105/3113/3115/3122/3123/3689/3108/3107/3134/3119/3109/3117/942/3118/3133/5880/3683/60/3127/4628/1605/3383/595/1756/1981/5881	HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/ITGB2/HLA-DMA/HLA-C/HLA-F/HLA-DQB1/HLA-DMB/HLA-DQA1/CD86/HLA-DQA2/HLA-E/RAC2/ITGAL/ACTB/HLA-DRB5/MYH10/DAG1/ICAM1/CCND1/DMD/EIF4G1/RAC3	27
hsa04940	Type I diabetes mellitus	19/936	43/5868	1.03544569462932e-05	0.000153837646059213	3106/3105/3113/3115/3122/3123/3108/3107/3134/3119/3109/3117/942/3118/3133/3127/7124/3329/3553	HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/HLA-C/HLA-F/HLA-DQB1/HLA-DMB/HLA-DQA1/CD86/HLA-DQA2/HLA-E/HLA-DRB5/TNF/HSPD1/IL1B	19
hsa04670	Leukocyte transendothelial migration	37/936	116/5868	1.2519376308299e-05	0.000173602018141747	3689/1536/7852/4688/4478/1535/653361/5175/5880/3683/60/83593/3684/3676/7408/1364/3688/1366/7409/2185/3383/4689/23533/5579/2771/387/83700/5906/2770/9564/7414/7430/10451/1500/5747/1432/81	ITGB2/CYBB/CXCR4/NCF2/MSN/CYBA/NCF1/PECAM1/RAC2/ITGAL/ACTB/RASSF5/ITGAM/ITGA4/VASP/CLDN4/ITGB1/CLDN7/VAV1/PTK2B/ICAM1/NCF4/PIK3R5/PRKCB/GNAI2/RHOA/JAM3/RAP1A/GNAI1/BCAR1/VCL/EZR/VAV3/CTNND1/PTK2/MAPK14/ACTN4	37
hsa05330	Allograft rejection	17/936	37/5868	1.61113891534781e-05	0.000209448058995215	3106/3105/3113/3115/3122/3123/3108/3107/3134/3119/3109/3117/942/3118/3133/3127/7124	HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/HLA-C/HLA-F/HLA-DQB1/HLA-DMB/HLA-DQA1/CD86/HLA-DQA2/HLA-E/HLA-DRB5/TNF	17
hsa05332	Graft-versus-host disease	18/936	41/5868	1.97411598875228e-05	0.000241003715927117	3106/3105/3113/3115/3122/3123/3108/3107/3134/3119/3109/3117/942/3118/3133/3127/7124/3553	HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/HLA-C/HLA-F/HLA-DQB1/HLA-DMB/HLA-DQA1/CD86/HLA-DQA2/HLA-E/HLA-DRB5/TNF/IL1B	18
hsa05130	Pathogenic Escherichia coli infection	22/936	56/5868	2.08560908013851e-05	0.000241003715927117	929/7454/23643/7846/60/10376/203068/999/7099/10094/3875/81873/3688/10383/84790/387/10093/10552/4691/3059/9181/7430	CD14/WAS/LY96/TUBA1A/ACTB/TUBA1B/TUBB/CDH1/TLR4/ARPC3/KRT18/ARPC5L/ITGB1/TUBB4B/TUBA1C/RHOA/ARPC4/ARPC1A/NCL/HCLS1/ARHGEF2/EZR	22
hsa05145	Toxoplasmosis	40/936	132/5868	2.20486153235528e-05	0.000241374315121	3113/3115/3122/3123/3108/3119/3109/3117/7040/23643/3118/3587/7097/3717/3655/3127/240/7124/7099/6772/3912/3716/3460/4792/4261/3911/3688/3915/23533/3312/330/2771/3310/6774/4615/2770/3303/572/3459/1432	HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DMB/HLA-DQA1/TGFB1/LY96/HLA-DQA2/IL10RA/TLR2/JAK2/ITGA6/HLA-DRB5/ALOX5/TNF/TLR4/STAT1/LAMB1/JAK1/IFNGR2/NFKBIA/CIITA/LAMA5/ITGB1/LAMC1/PIK3R5/HSPA8/BIRC3/GNAI2/HSPA6/STAT3/MYD88/GNAI1/HSPA1A/BAD/IFNGR1/MAPK14	40
hsa03040	Spliceosome	38/936	127/5868	4.80954496419463e-05	0.000500192676276241	6637/6632/6628/6636/6427/6635/220988/3178/3312/57819/3310/25804/27258/6634/23658/6627/55110/56259/51690/4116/10772/4809/84991/6432/3303/27316/10713/6434/23350/6625/10946/10594/6633/27339/9410/51729/51691/6429	SNRPG/SNRPD1/SNRPB/SNRPF/SRSF2/SNRPE/HNRNPA3/HNRNPA1/HSPA8/LSM2/HSPA6/LSM4/LSM3/SNRPD3/LSM5/SNRPA1/MAGOHB/CTNNBL1/LSM7/MAGOH/SRSF10/SNU13/RBM17/SRSF7/HSPA1A/RBMX/USP39/TRA2B/U2SURP/SNRNP70/SF3A3/PRPF8/SNRPD2/PRPF19/SNRNP40/WBP11/LSM8/SRSF4	38
hsa05016	Huntington's disease	49/936	183/5868	0.000101972751142943	0.00101001582084439	2876/6648/5441/7052/6647/1337/292/5330/9586/7019/4705/27089/4715/4710/4713/5437/54539/4700/3066/291/5435/4706/5438/1211/7416/1347/4723/4728/5440/4729/1345/1537/29796/7419/7385/4726/9377/548644/7386/1173/4718/51079/293/4716/161/6389/23186/5468/4702	GPX1/SOD2/POLR2L/TGM2/SOD1/COX6A1/SLC25A5/PLCB2/CREB5/TFAM/NDUFA10/UQCRQ/NDUFB9/NDUFB4/NDUFB7/POLR2H/NDUFB11/NDUFA6/HDAC2/SLC25A4/POLR2F/NDUFAB1/POLR2I/CLTA/VDAC1/COX7A2/NDUFV1/NDUFS8/POLR2K/NDUFV2/COX6C/CYC1/UQCR10/VDAC3/UQCRC2/NDUFS6/COX5A/POLR2J3/UQCRFS1/AP2M1/NDUFC2/NDUFA13/SLC25A6/NDUFB10/AP2A2/SDHA/RCOR1/PPARG/NDUFA8	49
hsa03420	Nucleotide excision repair	17/936	44/5868	0.000229126513547646	0.00216628703717774	5111/6119/5983/5984/5982/3978/6118/1642/5981/10714/54107/6117/57804/2067/5887/5425/5427	PCNA/RPA3/RFC3/RFC4/RFC2/LIG1/RPA2/DDB1/RFC1/POLD3/POLE3/RPA1/POLD4/ERCC1/RAD23B/POLD2/POLE2	17
hsa05100	Bacterial invasion of epithelial cells	23/936	70/5868	0.000335800261785899	0.00303680236745509	7454/2335/60/3678/999/10094/4233/81873/3688/23533/387/1211/10093/10552/10163/391/3059/9564/7414/79658/23607/2549/5747	WAS/FN1/ACTB/ITGA5/CDH1/ARPC3/MET/ARPC5L/ITGB1/PIK3R5/RHOA/CLTA/ARPC4/ARPC1A/WASF2/RHOG/HCLS1/BCAR1/VCL/ARHGAP10/CD2AP/GAB1/PTK2	23
hsa00240	Pyrimidine metabolism	29/936	99/5868	0.000546863468735817	0.00473948339571041	1890/1854/7378/7298/5441/6240/1806/978/1841/953/6241/7083/7372/5437/51728/10714/4860/5435/5438/5557/54107/4833/5440/5422/57804/5425/4830/548644/5427	TYMP/DUT/UPP1/TYMS/POLR2L/RRM1/DPYD/CDA/DTYMK/ENTPD1/RRM2/TK1/UMPS/POLR2H/POLR3K/POLD3/PNP/POLR2F/POLR2I/PRIM1/POLE3/NME4/POLR2K/POLA1/POLD4/POLD2/NME1/POLR2J3/POLE2	29
hsa03440	Homologous recombination	12/936	28/5868	0.000639042737660059	0.00531683557733169	6119/5888/6118/5889/641/10714/675/10111/6117/57804/5425/7516	RPA3/RAD51/RPA2/RAD51C/BLM/POLD3/BRCA2/RAD50/RPA1/POLD4/POLD2/XRCC2	12
hsa04640	Hematopoietic cell lineage	26/936	88/5868	0.000903737178156011	0.00722989742524809	3122/3123/929/951/960/2209/1436/928/3684/3678/3655/920/3127/7124/3553/948/3676/100133941/4311/912/3570/966/945/290/1438/7037	HLA-DRA/HLA-DRB1/CD14/CD37/CD44/FCGR1A/CSF1R/CD9/ITGAM/ITGA5/ITGA6/CD4/HLA-DRB5/TNF/IL1B/CD36/ITGA4/CD24/MME/CD1D/IL6R/CD59/CD33/ANPEP/CSF2RA/TFRC	26
hsa03410	Base excision repair	13/936	33/5868	0.00100250848147617	0.00772302830174233	3146/5111/142/2237/7374/3978/10714/54107/10038/328/57804/5425/5427	HMGB1/PCNA/PARP1/FEN1/UNG/LIG1/POLD3/POLE3/PARP2/APEX1/POLD4/POLD2/POLE2	13
hsa04666	Fc gamma R-mediated phagocytosis	27/936	94/5868	0.00116658653265863	0.00866607138546409	5788/2214/4082/2212/653361/2209/4067/7454/3055/5880/10094/7408/1794/6850/81873/7409/23533/5579/8877/8613/85477/10093/10552/10163/3635/10451/1072	PTPRC/FCGR3A/MARCKS/FCGR2A/NCF1/FCGR1A/LYN/WAS/HCK/RAC2/ARPC3/VASP/DOCK2/SYK/ARPC5L/VAV1/PIK3R5/PRKCB/SPHK1/PLPP3/SCIN/ARPC4/ARPC1A/WASF2/INPP5D/VAV3/CFL1	27
hsa04810	Regulation of actin cytoskeleton	51/936	213/5868	0.00133184885385402	0.00924918701279016	7114/3689/929/4478/3071/7454/2335/5880/3683/60/1956/3684/3678/3655/4628/3676/10094/3687/1445/81873/81624/3688/3691/7409/10788/6237/23533/3265/5962/387/55970/3693/3685/89846/85477/10093/10552/10163/5216/6548/9564/7414/7430/10451/56924/5747/1072/5154/3696/81/5881	TMSB4X/ITGB2/CD14/MSN/NCKAP1L/WAS/FN1/RAC2/ITGAL/ACTB/EGFR/ITGAM/ITGA5/ITGA6/MYH10/ITGA4/ARPC3/ITGAX/CSK/ARPC5L/DIAPH3/ITGB1/ITGB4/VAV1/IQGAP2/RRAS/PIK3R5/HRAS/RDX/RHOA/GNG12/ITGB5/ITGAV/FGD3/SCIN/ARPC4/ARPC1A/WASF2/PFN1/SLC9A1/BCAR1/VCL/EZR/VAV3/PAK6/PTK2/CFL1/PDGFA/ITGB8/ACTN4/RAC3	51
hsa05310	Asthma	12/936	30/5868	0.00133401735761397	0.00924918701279016	2207/3113/3115/3122/3123/3108/3119/3109/3117/3118/3127/7124	FCER1G/HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DMB/HLA-DQA1/HLA-DQA2/HLA-DRB5/TNF	12
hsa05012	Parkinson's disease	34/936	130/5868	0.00176747721777888	0.0118592019773551	9246/120892/1337/292/7314/4705/27089/4715/4710/4713/54539/4700/291/4706/7416/1347/4723/4728/4729/1345/11315/1537/29796/7419/7385/4726/9377/7386/4718/51079/293/4716/6389/4702	UBE2L6/LRRK2/COX6A1/SLC25A5/UBB/NDUFA10/UQCRQ/NDUFB9/NDUFB4/NDUFB7/NDUFB11/NDUFA6/SLC25A4/NDUFAB1/VDAC1/COX7A2/NDUFV1/NDUFS8/NDUFV2/COX6C/PARK7/CYC1/UQCR10/VDAC3/UQCRC2/NDUFS6/COX5A/UQCRFS1/NDUFC2/NDUFA13/SLC25A6/NDUFB10/SDHA/NDUFA8	34
hsa04662	B cell receptor signaling pathway	22/936	75/5868	0.00241891193045093	0.0157229275479311	4067/118788/11025/5880/2353/695/4792/6850/5777/7409/23533/5579/3265/27071/11261/2885/4794/3725/3635/10451/10725/5881	LYN/PIK3AP1/LILRB3/RAC2/FOS/BTK/NFKBIA/SYK/PTPN6/VAV1/PIK3R5/PRKCB/HRAS/DAPP1/CHP1/GRB2/NFKBIE/JUN/INPP5D/VAV3/NFAT5/RAC3	22
hsa05200	Pathways in cancer	71/936	326/5868	0.00270445606233205	0.0170462685140929	1436/6688/7040/2335/5880/2353/1956/83593/7422/3655/999/7184/2950/6772/6513/861/3912/4233/3716/4792/3320/3326/5914/1163/3911/3688/1284/3915/5888/595/898/6776/23533/5579/332/4436/3576/330/2034/3265/2956/387/7170/9134/6774/3066/1019/3685/2271/5899/2885/1282/675/7175/1021/1029/1438/3725/572/1026/3480/1017/2737/6502/6789/5747/5154/1869/10342/5468/5881	CSF1R/SPI1/TGFB1/FN1/RAC2/FOS/EGFR/RASSF5/VEGFA/ITGA6/CDH1/HSP90B1/GSTP1/STAT1/SLC2A1/RUNX1/LAMB1/MET/JAK1/NFKBIA/HSP90AA1/HSP90AB1/RARA/CKS1B/LAMA5/ITGB1/COL4A2/LAMC1/RAD51/CCND1/CCNE1/STAT5A/PIK3R5/PRKCB/BIRC5/MSH2/CXCL8/BIRC3/EPAS1/HRAS/MSH6/RHOA/TPM3/CCNE2/STAT3/HDAC2/CDK4/ITGAV/FH/RALB/GRB2/COL4A1/BRCA2/TPR/CDK6/CDKN2A/CSF2RA/JUN/BAD/CDKN1A/IGF1R/CDK2/GLI3/SKP2/STK4/PTK2/PDGFA/E2F1/TFG/PPARG/RAC3	71
hsa04621	NOD-like receptor signaling pathway	18/936	58/5868	0.00297721071630374	0.0182135243820934	29108/7184/834/7124/7128/3553/4792/3320/3326/114548/9051/4671/3576/330/22861/7205/3606/1432	PYCARD/HSP90B1/CASP1/TNF/TNFAIP3/IL1B/NFKBIA/HSP90AA1/HSP90AB1/NLRP3/PSTPIP1/NAIP/CXCL8/BIRC3/NLRP1/TRIP6/IL18/MAPK14	18
hsa00190	Oxidative phosphorylation	33/936	132/5868	0.00445450088622585	0.0264724624095708	1337/9296/4705/27089/4715/245973/4710/4713/54539/4700/4706/1347/4723/4728/4729/1345/525/1537/29796/7385/5464/10312/4726/526/9377/7386/4718/51079/8992/4716/6389/10063/4702	COX6A1/ATP6V1F/NDUFA10/UQCRQ/NDUFB9/ATP6V1C2/NDUFB4/NDUFB7/NDUFB11/NDUFA6/NDUFAB1/COX7A2/NDUFV1/NDUFS8/NDUFV2/COX6C/ATP6V1B1/CYC1/UQCR10/UQCRC2/PPA1/TCIRG1/NDUFS6/ATP6V1B2/COX5A/UQCRFS1/NDUFC2/NDUFA13/ATP6V0E1/NDUFB10/SDHA/COX17/NDUFA8	33
hsa04062	Chemokine signaling pathway	44/936	189/5868	0.00486229434149897	0.0280932561953274	414062/7852/6348/9560/653361/6351/4067/7454/3055/5880/2268/3717/1230/58191/6772/729230/409/3627/1794/4792/57580/1445/5330/7409/2185/23533/5579/1524/3576/2771/3265/10235/6773/387/55970/6774/56288/2885/5906/2770/9564/10451/59345/5747	CCL3L3/CXCR4/CCL3/CCL4L2/NCF1/CCL4/LYN/WAS/HCK/RAC2/FGR/JAK2/CCR1/CXCL16/STAT1/CCR2/ARRB2/CXCL10/DOCK2/NFKBIA/PREX1/CSK/PLCB2/VAV1/PTK2B/PIK3R5/PRKCB/CX3CR1/CXCL8/GNAI2/HRAS/RASGRP2/STAT2/RHOA/GNG12/STAT3/PARD3/GRB2/RAP1A/GNAI1/BCAR1/VAV3/GNB4/PTK2	44
hsa04510	Focal adhesion	46/936	200/5868	0.00514312384153305	0.0289126961902398	2316/2335/5880/60/1956/6696/7422/3678/3655/3676/7408/64098/3912/4233/3911/3688/3691/7409/1284/3915/595/23533/5579/2321/330/3265/896/387/3693/7791/3685/2885/1282/5906/3725/9564/7414/10451/572/3480/56924/5747/5154/3696/81/5881	FLNA/FN1/RAC2/ACTB/EGFR/SPP1/VEGFA/ITGA5/ITGA6/ITGA4/VASP/PARVG/LAMB1/MET/LAMA5/ITGB1/ITGB4/VAV1/COL4A2/LAMC1/CCND1/PIK3R5/PRKCB/FLT1/BIRC3/HRAS/CCND3/RHOA/ITGB5/ZYX/ITGAV/GRB2/COL4A1/RAP1A/JUN/BCAR1/VCL/VAV3/BAD/IGF1R/PAK6/PTK2/PDGFA/ITGB8/ACTN4/RAC3	46
hsa05131	Shigellosis	18/936	61/5868	0.00541967557198728	0.0291450142226243	960/7454/60/3678/10094/4792/1445/81873/3688/3576/10093/10552/10163/5216/391/3059/7414/1432	CD44/WAS/ACTB/ITGA5/ARPC3/NFKBIA/CSK/ARPC5L/ITGB1/CXCL8/ARPC4/ARPC1A/WASF2/PFN1/RHOG/HCLS1/VCL/MAPK14	18
hsa05320	Autoimmune thyroid disease	16/936	52/5868	0.00546469016674205	0.0291450142226243	3106/3105/3113/3115/3122/3123/3108/3107/3134/3119/3109/3117/942/3118/3133/3127	HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/HLA-C/HLA-F/HLA-DQB1/HLA-DMB/HLA-DQA1/CD86/HLA-DQA2/HLA-E/HLA-DRB5	16
hsa04672	Intestinal immune network for IgA production	15/936	48/5868	0.00600779524341027	0.0312405352657334	3113/3115/3122/3123/3108/7852/10673/3119/3109/3117/7040/942/3118/3127/3676	HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/CXCR4/TNFSF13B/HLA-DQB1/HLA-DMB/HLA-DQA1/TGFB1/CD86/HLA-DQA2/HLA-DRB5/ITGA4	15
hsa00270	Cysteine and methionine metabolism	12/936	36/5868	0.00768388792573292	0.0389816753305475	3945/10993/1786/259307/55256/1036/6611/3939/4507/6723/4548/58478	LDHB/SDS/DNMT1/IL4I1/ADI1/CDO1/SMS/LDHA/MTAP/SRM/MTR/ENOPH1	12
hsa04620	Toll-like receptor signaling pathway	26/936	102/5868	0.00836363390097711	0.0414199012238866	929/6348/6351/942/23643/7097/2353/6696/7096/7124/7099/3553/6772/3665/3627/10333/51284/4792/23533/3663/51311/3576/1326/4615/3725/1432	CD14/CCL3/CCL4/CD86/LY96/TLR2/FOS/SPP1/TLR1/TNF/TLR4/IL1B/STAT1/IRF7/CXCL10/TLR6/TLR7/NFKBIA/PIK3R5/IRF5/TLR8/CXCL8/MAP3K8/MYD88/JUN/MAPK14	26
hsa04520	Adherens junction	20/936	73/5868	0.00860731933442552	0.04163540515257	7454/5880/60/1956/999/4233/5777/4008/387/56288/7082/5792/10163/7414/3480/7525/3643/1500/81/5881	WAS/RAC2/ACTB/EGFR/CDH1/MET/PTPN6/LMO7/RHOA/PARD3/TJP1/PTPRF/WASF2/VCL/IGF1R/YES1/INSR/CTNND1/ACTN4/RAC3	20
hsa05142	Chagas disease (American trypanosomiasis)	26/936	104/5868	0.01085490049117	0.0508820186315813	414062/6348/7040/7097/2353/7124/7099/3553/2778/718/10333/3460/4792/5330/811/712/2769/23533/3576/2771/4615/2767/2770/3725/3459/1432	CCL3L3/CCL3/TGFB1/TLR2/FOS/TNF/TLR4/IL1B/GNAS/C3/TLR6/IFNGR2/NFKBIA/PLCB2/CALR/C1QA/GNA15/PIK3R5/CXCL8/GNAI2/MYD88/GNA11/GNAI1/JUN/IFNGR1/MAPK14	26
hsa05144	Malaria	15/936	51/5868	0.011008129030871	0.0508820186315813	3689/5175/7040/7097/3683/7124/7099/3553/948/2995/4233/3383/3576/4615/3606	ITGB2/PECAM1/TGFB1/TLR2/ITGAL/TNF/TLR4/IL1B/CD36/GYPC/MET/ICAM1/CXCL8/MYD88/IL18	15
hsa05222	Small cell lung cancer	22/936	85/5868	0.0121674950850895	0.0550182386456219	2335/3655/3912/4792/1163/3911/3688/1284/3915/595/898/23533/330/9134/1019/3685/1282/1021/1017/6502/5747/1869	FN1/ITGA6/LAMB1/NFKBIA/CKS1B/LAMA5/ITGB1/COL4A2/LAMC1/CCND1/CCNE1/PIK3R5/BIRC3/CCNE2/CDK4/ITGAV/COL4A1/CDK6/CDK2/SKP2/PTK2/E2F1	22
hsa04650	Natural killer cell mediated cytotoxicity	32/936	136/5868	0.0128246891992175	0.0567560713497287	3106/7305/2207/3105/2214/3689/3107/8743/10870/962/3133/5880/3683/7124/3937/6452/3460/6850/5777/3384/7409/2185/3383/23533/5579/3265/11261/2885/10451/3459/10725/5881	HLA-B/TYROBP/FCER1G/HLA-A/FCGR3A/ITGB2/HLA-C/TNFSF10/HCST/CD48/HLA-E/RAC2/ITGAL/TNF/LCP2/SH3BP2/IFNGR2/SYK/PTPN6/ICAM2/VAV1/PTK2B/ICAM1/PIK3R5/PRKCB/HRAS/CHP1/GRB2/VAV3/IFNGR1/NFAT5/RAC3	32
hsa04115	p53 signaling pathway	18/936	68/5868	0.0176115156710254	0.0763165679077766	64065/983/4616/595/6241/898/1111/5366/896/9134/1019/51512/1021/1029/6477/9538/1026/1017	PERP/CDK1/GADD45B/CCND1/RRM2/CCNE1/CHEK1/PMAIP1/CCND3/CCNE2/CDK4/GTSE1/CDK6/CDKN2A/SIAH1/EI24/CDKN1A/CDK2	18
hsa00480	Glutathione metabolism	14/936	50/5868	0.0212946493424181	0.0903936135351624	2876/79017/4259/2950/6240/51056/6241/3418/6611/290/2730/4257/6723/3417	GPX1/GGCT/MGST3/GSTP1/RRM1/LAP3/RRM2/IDH2/SMS/ANPEP/GCLM/MGST1/SRM/IDH1	14
hsa05212	Pancreatic cancer	18/936	70/5868	0.0234996370170246	0.0977584899908225	7040/5880/1956/7422/6772/3716/5888/595/23533/6774/1019/5899/675/1021/1029/572/1869/5881	TGFB1/RAC2/EGFR/VEGFA/STAT1/JAK1/RAD51/CCND1/PIK3R5/STAT3/CDK4/RALB/BRCA2/CDK6/CDKN2A/BAD/E2F1/RAC3	18
hsa05146	Amoebiasis	25/936	106/5868	0.0251187572222164	0.10244512749453	3689/929/7040/7097/2335/3684/7124/7099/3553/2778/3912/3911/912/5330/1284/3915/2769/23533/5579/3576/1282/2767/7414/5747/81	ITGB2/CD14/TGFB1/TLR2/FN1/ITGAM/TNF/TLR4/IL1B/GNAS/LAMB1/LAMA5/CD1D/PLCB2/COL4A2/LAMC1/GNA15/PIK3R5/PRKCB/CXCL8/COL4A1/GNA11/VCL/PTK2/ACTN4	25
hsa05219	Bladder cancer	12/936	42/5868	0.0272731256901892	0.109092502760757	1890/1956/7422/999/595/3576/3265/1019/1029/1026/9252/1869	TYMP/EGFR/VEGFA/CDH1/CCND1/CXCL8/HRAS/CDK4/CDKN2A/CDKN1A/RPS6KA5/E2F1	12
hsa05010	Alzheimer's disease	36/936	167/5868	0.0322130229282692	0.126420920171321	7124/3553/351/4311/1337/5330/8883/4705/27089/4715/11261/805/4710/4713/54539/4700/4706/1347/4723/4728/4729/1345/1537/29796/7385/572/4726/9377/7386/4718/823/51079/4716/6389/2597/4702	TNF/IL1B/APP/MME/COX6A1/PLCB2/NAE1/NDUFA10/UQCRQ/NDUFB9/CHP1/CALM2/NDUFB4/NDUFB7/NDUFB11/NDUFA6/NDUFAB1/COX7A2/NDUFV1/NDUFS8/NDUFV2/COX6C/CYC1/UQCR10/UQCRC2/BAD/NDUFS6/COX5A/UQCRFS1/NDUFC2/CAPN1/NDUFA13/NDUFB10/SDHA/GAPDH/NDUFA8	36
hsa05120	Epithelial cell signaling in Helicobacter pylori infection	17/936	68/5868	0.0351663068595468	0.135455404199736	4067/1956/4233/4792/1445/9296/1839/3576/245973/83700/7082/3725/525/10312/526/8992/1432	LYN/EGFR/MET/NFKBIA/CSK/ATP6V1F/HBEGF/CXCL8/ATP6V1C2/JAM3/TJP1/JUN/ATP6V1B1/TCIRG1/ATP6V1B2/ATP6V0E1/MAPK14	17
hsa05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/936	74/5868	0.039604117145843	0.149775570297006	6546/60/3678/3655/1832/3676/1605/3688/3691/1829/2697/1824/3693/3685/1756/4000/3696/81	SLC8A1/ACTB/ITGA5/ITGA6/DSP/ITGA4/DAG1/ITGB1/ITGB4/DSG2/GJA1/DSC2/ITGB5/ITGAV/DMD/LMNA/ITGB8/ACTN4	18
hsa04141	Protein processing in endoplasmic reticulum	35/936	165/5868	0.0424666704561292	0.157375865439397	7184/3998/5034/6238/10130/6185/3320/1650/3326/7991/2923/811/9601/3309/10961/3312/3310/26270/7321/9532/258010/23193/10970/11231/440275/5887/3303/27102/23645/64215/64374/7415/823/10277/22872	HSP90B1/LMAN1/P4HB/RRBP1/PDIA6/RPN2/HSP90AA1/DDOST/HSP90AB1/TUSC3/PDIA3/CALR/PDIA4/HSPA5/ERP29/HSPA8/HSPA6/FBXO6/UBE2D1/BAG2/SVIP/GANAB/CKAP4/SEC63/EIF2AK4/RAD23B/HSPA1A/EIF2AK1/PPP1R15A/DNAJC1/SIL1/VCP/CAPN1/UBE4B/SEC31A	35
hsa03450	Non-homologous end-joining	5/936	13/5868	0.0431270400482963	0.157375865439397	5591/2237/7520/10111/2547	PRKDC/FEN1/XRCC5/RAD50/XRCC6	5
hsa00620	Pyruvate metabolism	11/936	40/5868	0.0439150847729714	0.157488579875484	217/3945/84532/501/231/3939/9380/39/5160/4190/2739	ALDH2/LDHB/ACSS1/ALDH7A1/AKR1B1/LDHA/GRHPR/ACAT2/PDHA1/MDH1/GLO1	11
hsa05214	Glioma	16/936	65/5868	0.0457730736630452	0.161369480032431	1956/595/23533/5579/817/3265/805/1019/2885/1021/1029/818/1026/3480/5154/1869	EGFR/CCND1/PIK3R5/PRKCB/CAMK2D/HRAS/CALM2/CDK4/GRB2/CDK6/CDKN2A/CAMK2G/CDKN1A/IGF1R/PDGFA/E2F1	16
hsa04142	Lysosome	26/936	121/5868	0.063885141839276	0.22146849170949	7805/1520/968/6556/8905/10577/1508/5660/1514/1512/1509/1522/1515/5538/1200/2517/967/3423/3988/130340/1211/54/1174/10312/2548/3074	LAPTM5/CTSS/CD68/SLC11A1/AP1S2/NPC2/CTSB/PSAP/CTSL/CTSH/CTSD/CTSZ/CTSV/PPT1/TPP1/FUCA1/CD63/IDS/LIPA/AP1S3/CLTA/ACP5/AP1S1/TCIRG1/GAA/HEXB	26
hsa04540	Gap junction	20/936	90/5868	0.07206265959999	0.245721855685212	7846/1956/10376/203068/2778/983/10383/5330/84790/5579/2697/2771/3265/153/10746/2885/7082/2767/2770/5154	TUBA1A/EGFR/TUBA1B/TUBB/GNAS/CDK1/TUBB4B/PLCB2/TUBA1C/PRKCB/GJA1/GNAI2/HRAS/ADRB1/MAP3K2/GRB2/TJP1/GNA11/GNAI1/PDGFA	20
hsa04512	ECM-receptor interaction	19/936	85/5868	0.0744488167040258	0.249763772168344	960/2335/6696/3678/3655/948/3676/3912/1605/3911/3688/3691/1284/3915/3693/3161/3685/1282/3696	CD44/FN1/SPP1/ITGA5/ITGA6/CD36/ITGA4/LAMB1/DAG1/LAMA5/ITGB1/ITGB4/COL4A2/LAMC1/ITGB5/HMMR/ITGAV/COL4A1/ITGB8	19
hsa05110	Vibrio cholerae infection	13/936	54/5868	0.0783970597548907	0.254790444203395	60/2778/9296/3784/9601/5579/245973/7082/525/10312/526/8992/11014	ACTB/GNAS/ATP6V1F/KCNQ1/PDIA4/PRKCB/ATP6V1C2/TJP1/ATP6V1B1/TCIRG1/ATP6V1B2/ATP6V0E1/KDELR2	13
hsa05223	Non-small cell lung cancer	13/936	54/5868	0.0783970597548907	0.254790444203395	1956/83593/595/23533/5579/3265/1019/2885/1021/1029/572/6789/1869	EGFR/RASSF5/CCND1/PIK3R5/PRKCB/HRAS/CDK4/GRB2/CDK6/CDKN2A/BAD/STK4/E2F1	13
hsa00790	Folate biosynthesis	4/936	11/5868	0.0835933181656876	0.2674986181302	8836/1719/2643/5860	GGH/DHFR/GCH1/QDPR	4
hsa05215	Prostate cancer	19/936	89/5868	0.107312215573266	0.338196073321807	1956/7184/2950/4792/3320/3326/9586/595/898/23533/3265/9134/2885/572/1026/3480/1017/5154/1869	EGFR/HSP90B1/GSTP1/NFKBIA/HSP90AA1/HSP90AB1/CREB5/CCND1/CCNE1/PIK3R5/HRAS/CCNE2/GRB2/BAD/CDKN1A/IGF1R/CDK2/PDGFA/E2F1	19
hsa00410	beta-Alanine metabolism	6/936	22/5868	0.125184061752698	0.383315753571758	217/1806/1892/501/6611/6723	ALDH2/DPYD/ECHS1/ALDH7A1/SMS/SRM	6
hsa00640	Propanoate metabolism	8/936	32/5868	0.125314765590767	0.383315753571758	217/3945/84532/1892/501/3939/39/8802	ALDH2/LDHB/ACSS1/ECHS1/ALDH7A1/LDHA/ACAT2/SUCLG1	8
hsa04660	T cell receptor signaling pathway	22/936	108/5868	0.129792695362974	0.391259139644908	5788/2353/920/7124/3937/4792/5777/7409/23533/3265/11261/387/1326/1019/2885/4794/3725/10451/1739/56924/1432/10725	PTPRC/FOS/CD4/TNF/LCP2/NFKBIA/PTPN6/VAV1/PIK3R5/HRAS/CHP1/RHOA/MAP3K8/CDK4/GRB2/NFKBIE/JUN/VAV3/DLG1/PAK6/MAPK14/NFAT5	22
hsa00071	Fatty acid degradation	10/936	43/5868	0.135958139919352	0.403989901474646	217/1632/1892/501/128/37/3033/2182/39/10455	ALDH2/ECI1/ECHS1/ALDH7A1/ADH5/ACADVL/HADH/ACSL4/ACAT2/ECI2	10
hsa00330	Arginine and proline metabolism	12/936	54/5868	0.141285249570033	0.41390608324742	217/51056/6303/2752/501/6611/4942/445/6723/29920/112483/1159	ALDH2/LAP3/SAT1/GLUL/ALDH7A1/SMS/OAT/ASS1/SRM/PYCR2/SAT2/CKMT1B	12
hsa05410	Hypertrophic cardiomyopathy (HCM)	17/936	83/5868	0.16181179375768	0.467456293077741	7040/6546/60/3678/3655/7124/3676/1605/3688/3691/7170/3693/3685/1756/4000/3696/51422	TGFB1/SLC8A1/ACTB/ITGA5/ITGA6/TNF/ITGA4/DAG1/ITGB1/ITGB4/TPM3/ITGB5/ITGAV/DMD/LMNA/ITGB8/PRKAG2	17
hsa03020	RNA polymerase	7/936	29/5868	0.168053894626123	0.472367703813968	5441/5437/51728/5435/5438/5440/548644	POLR2L/POLR2H/POLR3K/POLR2F/POLR2I/POLR2K/POLR2J3	7
hsa05216	Thyroid cancer	7/936	29/5868	0.168053894626123	0.472367703813968	999/595/3265/7170/7175/10342/5468	CDH1/CCND1/HRAS/TPM3/TPR/TFG/PPARG	7
hsa04623	Cytosolic DNA-sensing pathway	12/936	56/5868	0.17156459385351	0.475805806953734	9560/6351/29108/834/3553/3665/3627/4792/9447/51728/23586/3606	CCL4L2/CCL4/PYCARD/CASP1/IL1B/IRF7/CXCL10/NFKBIA/AIM2/POLR3K/DDX58/IL18	12
hsa00100	Steroid biosynthesis	5/936	19/5868	0.174238640979151	0.476863648995571	1718/6713/2222/3988/10682	DHCR24/SQLE/FDFT1/LIPA/EBP	5
hsa05220	Chronic myeloid leukemia	15/936	73/5868	0.177381517321394	0.477819121670497	7040/861/4792/595/6776/23533/3265/3066/1019/2885/1021/1029/572/1026/1869	TGFB1/RUNX1/NFKBIA/CCND1/STAT5A/PIK3R5/HRAS/HDAC2/CDK4/GRB2/CDK6/CDKN2A/BAD/CDKN1A/E2F1	15
hsa05414	Dilated cardiomyopathy	18/936	90/5868	0.179182170626436	0.477819121670497	7040/6546/60/3678/3655/7124/3676/2778/1605/3688/3691/153/7170/3693/3685/1756/4000/3696	TGFB1/SLC8A1/ACTB/ITGA5/ITGA6/TNF/ITGA4/GNAS/DAG1/ITGB1/ITGB4/ADRB1/TPM3/ITGB5/ITGAV/DMD/LMNA/ITGB8	18
hsa04664	Fc epsilon RI signaling pathway	16/936	79/5868	0.182877871846209	0.477934369964774	2207/4067/5880/7124/3937/695/6850/7409/23533/5579/3265/2885/3635/10451/1432/5881	FCER1G/LYN/RAC2/TNF/LCP2/BTK/SYK/VAV1/PIK3R5/PRKCB/HRAS/GRB2/INPP5D/VAV3/MAPK14/RAC3	16
hsa05340	Primary immunodeficiency	8/936	35/5868	0.183820911524913	0.477934369964774	5788/920/6891/6890/695/3561/4261/7374	PTPRC/CD4/TAP2/TAP1/BTK/IL2RG/CIITA/UNG	8
hsa00020	Citrate cycle (TCA cycle)	7/936	30/5868	0.190996371413669	0.49045981795115	3418/2271/5160/4190/3417/8802/6389	IDH2/FH/PDHA1/MDH1/IDH1/SUCLG1/SDHA	7
hsa05160	Hepatitis C	25/936	134/5868	0.224344530563482	0.569069053136638	4939/1956/3434/7124/6772/3665/9021/3716/4792/1364/1366/3659/4938/23533/3576/3265/6773/6774/2885/440275/27102/572/1026/23586/1432	OAS2/EGFR/IFIT1/TNF/STAT1/IRF7/SOCS3/JAK1/NFKBIA/CLDN4/CLDN7/IRF1/OAS1/PIK3R5/CXCL8/HRAS/STAT2/STAT3/GRB2/EIF2AK4/EIF2AK1/BAD/CDKN1A/DDX58/MAPK14	25
hsa05218	Melanoma	14/936	71/5868	0.233521711246447	0.585211035412782	1956/999/4233/595/23533/3265/1019/1021/1029/572/1026/3480/5154/1869	EGFR/CDH1/MET/CCND1/PIK3R5/HRAS/CDK4/CDK6/CDKN2A/BAD/CDKN1A/IGF1R/PDGFA/E2F1	14
hsa04966	Collecting duct acid secretion	6/936	27/5868	0.253178617706682	0.626918481940354	9296/245973/525/10312/526/8992	ATP6V1F/ATP6V1C2/ATP6V1B1/TCIRG1/ATP6V1B2/ATP6V0E1	6
hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	5/936	22/5868	0.267085528933447	0.653574000213611	79586/51363/113189/29940/26229	CHPF/CHST15/CHST14/DSE/B3GAT3	5
hsa05210	Colorectal cancer	12/936	62/5868	0.278325301930275	0.673158869784852	7040/5880/2353/595/23533/332/4436/2956/387/3725/572/5881	TGFB1/RAC2/FOS/CCND1/PIK3R5/BIRC5/MSH2/MSH6/RHOA/JUN/BAD/RAC3	12
hsa05211	Renal cell carcinoma	13/936	70/5868	0.32015511456638	0.732845552888205	7040/7422/6513/4233/23533/2034/3265/2271/2885/5906/3725/56924/2549	TGFB1/VEGFA/SLC2A1/MET/PIK3R5/EPAS1/HRAS/FH/GRB2/RAP1A/JUN/PAK6/GAB1	13
hsa05020	Prion diseases	7/936	35/5868	0.320308620083184	0.732845552888205	3553/6647/4851/712/3915/3309/3303	IL1B/SOD1/NOTCH1/C1QA/LAMC1/HSPA5/HSPA1A	7
hsa05143	African trypanosomiasis	7/936	35/5868	0.320308620083184	0.732845552888205	7124/3553/5330/3383/5579/4615/3606	TNF/IL1B/PLCB2/ICAM1/PRKCB/MYD88/IL18	7
hsa00630	Glyoxylate and dicarboxylate metabolism	4/936	18/5868	0.32061992938859	0.732845552888205	283871/9380/39/4190	PGP/GRHPR/ACAT2/MDH1	4
hsa00670	One carbon pool by folate	4/936	18/5868	0.32061992938859	0.732845552888205	7298/1719/6470/4548	TYMS/DHFR/SHMT1/MTR	4
hsa00010	Glycolysis / Gluconeogenesis	12/936	65/5868	0.338177696644604	0.759474976771583	217/2203/3945/84532/3101/501/128/3099/226/3939/5160/2597	ALDH2/FBP1/LDHB/ACSS1/HK3/ALDH7A1/ADH5/HK2/ALDOA/LDHA/PDHA1/GAPDH	12
hsa03018	RNA degradation	13/936	71/5868	0.339572946344987	0.759474976771583	10950/3329/26986/7832/11340/694/57819/25804/27258/23658/51690/51691/3313	BTG3/HSPD1/PABPC1/BTG2/EXOSC8/BTG1/LSM2/LSM4/LSM3/LSM5/LSM7/LSM8/HSPA9	13
hsa00230	Purine metabolism	28/936	162/5868	0.351518772040434	0.777828772174578	5441/6240/10606/953/5141/6241/5437/51728/10714/4860/5435/8833/5438/5557/54107/4833/132/3615/11164/5440/5422/57804/272/5425/4830/548644/5471/5427	POLR2L/RRM1/PAICS/ENTPD1/PDE4A/RRM2/POLR2H/POLR3K/POLD3/PNP/POLR2F/GMPS/POLR2I/PRIM1/POLE3/NME4/ADK/IMPDH2/NUDT5/POLR2K/POLA1/POLD4/AMPD3/POLD2/NME1/POLR2J3/PPAT/POLE2	28
hsa04722	Neurotrophin signaling pathway	22/936	127/5868	0.371323879283752	0.813003862010741	397/11213/9500/4792/1445/10019/23533/817/3265/387/805/6195/2885/5906/4794/7531/3725/818/572/2549/9252/1432	ARHGDIB/IRAK3/MAGED1/NFKBIA/CSK/SH2B3/PIK3R5/CAMK2D/HRAS/RHOA/CALM2/RPS6KA1/GRB2/RAP1A/NFKBIE/YWHAE/JUN/CAMK2G/BAD/GAB1/RPS6KA5/MAPK14	22
hsa04144	Endocytosis	34/936	201/5868	0.381720539862663	0.827061169702435	3106/3105/7852/3107/3134/1436/7040/3133/1956/409/4233/3561/2321/3312/3265/3310/153/64744/387/56288/22905/2348/56904/1211/84612/3303/3480/7037/92421/84313/1173/161/8411/26119	HLA-B/HLA-A/CXCR4/HLA-C/HLA-F/CSF1R/TGFB1/HLA-E/EGFR/ARRB2/MET/IL2RG/FLT1/HSPA8/HRAS/HSPA6/ADRB1/SMAP2/RHOA/PARD3/EPN2/FOLR1/SH3GLB2/CLTA/PARD6B/HSPA1A/IGF1R/TFRC/CHMP4C/VPS25/AP2M1/AP2A2/EEA1/LDLRAP1	34
hsa04971	Gastric acid secretion	13/936	74/5868	0.398983994163717	0.847822813248898	60/2778/5330/3784/5579/817/3274/2771/805/2770/6548/818/7430	ACTB/GNAS/PLCB2/KCNQ1/PRKCB/CAMK2D/HRH2/GNAI2/CALM2/GNAI1/SLC9A1/CAMK2G/EZR	13
hsa04360	Axon guidance	22/936	129/5868	0.401506966679568	0.847822813248898	7852/5880/10154/4233/3688/64218/57556/5921/2771/3265/11261/8829/387/2050/80031/1942/2770/56924/5747/1072/10725/5881	CXCR4/RAC2/PLXNC1/MET/ITGB1/SEMA4A/SEMA6A/RASA1/GNAI2/HRAS/CHP1/NRP1/RHOA/EPHB4/SEMA6D/EFNA1/GNAI1/PAK6/PTK2/CFL1/NFAT5/RAC3	22
hsa00250	Alanine, aspartate and glutamate metabolism	6/936	32/5868	0.403531050536735	0.847822813248898	2752/259307/445/56954/2673/5471	GLUL/IL4I1/ASS1/NIT2/GFPT1/PPAT	6
hsa04012	ErbB signaling pathway	15/936	87/5868	0.414865982764364	0.862921244149878	1956/6776/23533/5579/1839/817/3265/2885/3725/818/572/1026/56924/2549/5747	EGFR/STAT5A/PIK3R5/PRKCB/HBEGF/CAMK2D/HRAS/GRB2/JUN/CAMK2G/BAD/CDKN1A/PAK6/GAB1/PTK2	15
hsa05221	Acute myeloid leukemia	10/936	57/5868	0.425438326472767	0.876150216894412	6688/861/5914/595/6776/23533/3265/6774/2885/572	SPI1/RUNX1/RARA/CCND1/STAT5A/PIK3R5/HRAS/STAT3/GRB2/BAD	10
hsa00052	Galactose metabolism	5/936	27/5868	0.435857255751225	0.878043220965051	3101/3099/231/7360/2548	HK3/HK2/AKR1B1/UGP2/GAA	5
hsa00900	Terpenoid backbone biosynthesis	3/936	15/5868	0.437184012421111	0.878043220965051	2224/39/10654	FDPS/ACAT2/PMVK	3
hsa04370	VEGF signaling pathway	13/936	76/5868	0.439021610482526	0.878043220965051	5880/7422/23533/5579/3265/11261/8877/7867/572/5747/1432/10725/5881	RAC2/VEGFA/PIK3R5/PRKCB/HRAS/CHP1/SPHK1/MAPKAPK3/BAD/PTK2/MAPK14/NFAT5/RAC3	13
hsa05014	Amyotrophic lateral sclerosis (ALS)	9/936	53/5868	0.476104416615447	0.943140177676314	7133/2876/834/7124/6647/11261/10452/572/1432	TNFRSF1B/GPX1/CASP1/TNF/SOD1/CHP1/TOMM40/BAD/MAPK14	9
hsa04330	Notch signaling pathway	8/936	47/5868	0.481379598682374	0.944593929489941	4851/3955/4242/4853/3066/9612/151636/8650	NOTCH1/LFNG/MFNG/NOTCH2/HDAC2/NCOR2/DTX3L/NUMB	8
hsa03008	Ribosome biogenesis in eukaryotes	13/936	79/5868	0.498698893419032	0.960457128066285	5901/10248/10528/55651/51602/29107/4809/6949/26354/55272/51119/2091/9790	RAN/POP7/NOP56/NHP2/NOP58/NXT1/SNU13/TCOF1/GNL3/IMP3/SBDS/FBL/BMS1	13
hsa04146	Peroxisome	13/936	79/5868	0.498698893419032	0.960457128066285	6648/11001/25824/6647/5827/3418/2182/10654/5052/3417/10455/10478/1891	SOD2/SLC27A2/PRDX5/SOD1/PXMP2/IDH2/ACSL4/PMVK/PRDX1/IDH1/ECI2/SLC25A17/ECH1	13
hsa04914	Progesterone-mediated oocyte maturation	14/936	86/5868	0.512604549178133	0.972610521984293	3320/3326/983/4085/51529/23533/2771/890/9088/6195/2770/3480/1017/1432	HSP90AA1/HSP90AB1/CDK1/MAD2L1/ANAPC11/PIK3R5/GNAI2/CCNA2/PKMYT1/RPS6KA1/GNAI1/IGF1R/CDK2/MAPK14	14
hsa00380	Tryptophan metabolism	7/936	42/5868	0.514361333741693	0.972610521984293	217/8942/259307/1892/501/3033/39	ALDH2/KYNU/IL4I1/ECHS1/ALDH7A1/HADH/ACAT2	7
hsa00051	Fructose and mannose metabolism	6/936	36/5868	0.523238386510952	0.974221849283988	2203/3101/3099/231/226/29085	FBP1/HK3/HK2/AKR1B1/ALDOA/PHPT1	6
hsa04614	Renin-angiotensin system	3/936	17/5868	0.524580995768301	0.974221849283988	4311/2028/290	MME/ENPEP/ANPEP	3
hsa04920	Adipocytokine signaling pathway	11/936	68/5868	0.531185141471771	0.977756720585207	7133/3717/7124/948/6513/9021/4792/6774/2182/4794/51422	TNFRSF1B/JAK2/TNF/CD36/SLC2A1/SOCS3/NFKBIA/STAT3/ACSL4/NFKBIE/PRKAG2	11
hsa00290	Valine, leucine and isoleucine biosynthesis	2/936	11/5868	0.543642670267613	0.980320718395445	55699/5160	IARS2/PDHA1	2
hsa04320	Dorso-ventral axis formation	4/936	24/5868	0.547298744929615	0.980320718395445	1956/4851/4853/2885	EGFR/NOTCH1/NOTCH2/GRB2	4
hsa04610	Complement and coagulation cascades	11/936	69/5868	0.552061038722545	0.980320718395445	5265/728/5329/719/1675/2153/718/4179/712/966/710	SERPINA1/C5AR1/PLAUR/C3AR1/CFD/F5/C3/CD46/C1QA/CD59/SERPING1	11
hsa04912	GnRH signaling pathway	16/936	101/5868	0.554714498680372	0.980320718395445	1956/2778/5330/2185/5579/1839/817/3265/805/10746/2885/2767/3725/818/4216/1432	EGFR/GNAS/PLCB2/PTK2B/PRKCB/HBEGF/CAMK2D/HRAS/CALM2/MAP3K2/GRB2/GNA11/JUN/CAMK2G/MAP3K4/MAPK14	16
hsa00561	Glycerolipid metabolism	8/936	50/5868	0.556143484474339	0.980320718395445	217/501/10555/231/8613/8527/11343/2710	ALDH2/ALDH7A1/AGPAT2/AKR1B1/PLPP3/DGKD/MGLL/GK	8
hsa00310	Lysine degradation	7/936	44/5868	0.566851914810822	0.990799985551689	217/1892/501/3033/39/387893/5352	ALDH2/ECHS1/ALDH7A1/HADH/ACAT2/KMT5A/PLOD2	7
hsa04260	Cardiac muscle contraction	12/936	77/5868	0.583784146136848	1	6546/1337/27089/7170/1347/6548/1345/1537/29796/7385/9377/7386	SLC8A1/COX6A1/UQCRQ/TPM3/COX7A2/SLC9A1/COX6C/CYC1/UQCR10/UQCRC2/COX5A/UQCRFS1	12
hsa05322	Systemic lupus erythematosus	21/936	136/5868	0.602047790907163	1	3113/3115/3122/3123/2214/3108/2212/2209/3119/3109/3117/942/3118/3127/7124/718/6632/6628/712/6634/81	HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/FCGR3A/HLA-DMA/FCGR2A/FCGR1A/HLA-DQB1/HLA-DMB/HLA-DQA1/CD86/HLA-DQA2/HLA-DRB5/TNF/C3/SNRPD1/SNRPB/C1QA/SNRPD3/ACTN4	21
hsa00983	Drug metabolism - other enzymes	8/936	52/5868	0.603344561852369	1	1890/7378/1806/978/7083/7372/8833/3615	TYMP/UPP1/DPYD/CDA/TK1/UMPS/GMPS/IMPDH2	8
hsa00531	Glycosaminoglycan degradation	3/936	19/5868	0.603945384559206	1	10855/3423/3074	HPSE/IDS/HEXB	3
hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	4/936	26/5868	0.614078546642718	1	2135/9957/26229/90161	EXTL2/HS3ST1/B3GAT3/HS6ST2	4
hsa04530	Tight junction	20/936	132/5868	0.637180516189959	1	60/4628/1364/1366/6237/5579/2771/3265/387/56288/1019/83700/7082/2770/3059/84612/7525/2035/154810/81	ACTB/MYH10/CLDN4/CLDN7/RRAS/PRKCB/GNAI2/HRAS/RHOA/PARD3/CDK4/JAM3/TJP1/GNAI1/HCLS1/PARD6B/YES1/EPB41/AMOTL1/ACTN4	20
hsa04010	MAPK signaling pathway	41/936	268/5868	0.643830358674788	1	929/7040/2316/4208/1843/5880/2353/1956/3925/7124/1852/3553/1844/409/4616/3164/6237/5579/5921/3312/3265/11261/3310/10235/10746/55970/6195/11072/7867/1326/2885/5906/1847/3725/3303/6789/4216/9252/5154/1432/5881	CD14/TGFB1/FLNA/MEF2C/DUSP1/RAC2/FOS/EGFR/STMN1/TNF/DUSP9/IL1B/DUSP2/ARRB2/GADD45B/NR4A1/RRAS/PRKCB/RASA1/HSPA8/HRAS/CHP1/HSPA6/RASGRP2/MAP3K2/GNG12/RPS6KA1/DUSP14/MAPKAPK3/MAP3K8/GRB2/RAP1A/DUSP5/JUN/HSPA1A/STK4/MAP3K4/RPS6KA5/PDGFA/MAPK14/RAC3	41
hsa04974	Protein digestion and absorption	12/936	81/5868	0.657461323394536	1	6546/9056/7373/4311/1803/3784/1284/10008/6510/1282/3783/6520	SLC8A1/SLC7A7/COL14A1/MME/DPP4/KCNQ1/COL4A2/KCNE3/SLC1A5/COL4A1/KCNN4/SLC3A2	12
hsa00520	Amino sugar and nucleotide sugar metabolism	7/936	48/5868	0.66302475363955	1	3101/3099/80146/7360/51706/3074/2673	HK3/HK2/UXS1/UGP2/CYB5R1/HEXB/GFPT1	7
hsa04060	Cytokine-cytokine receptor interaction	40/936	265/5868	0.677817329498947	1	414062/7852/6348/10673/9560/8743/7133/1436/6351/7040/3587/1956/7422/8764/1230/7124/58191/3553/729230/3627/4233/3561/3460/655/80301/8742/3570/2321/1524/3576/84957/3597/1439/3572/51330/23765/1438/3459/5154/3606	CCL3L3/CXCR4/CCL3/TNFSF13B/CCL4L2/TNFSF10/TNFRSF1B/CSF1R/CCL4/TGFB1/IL10RA/EGFR/VEGFA/TNFRSF14/CCR1/TNF/CXCL16/IL1B/CCR2/CXCL10/MET/IL2RG/IFNGR2/BMP7/PLEKHO2/TNFSF12/IL6R/FLT1/CX3CR1/CXCL8/RELT/IL13RA1/CSF2RB/IL6ST/TNFRSF12A/IL17RA/CSF2RA/IFNGR1/PDGFA/IL18	40
hsa04630	Jak-STAT signaling pathway	23/936	155/5868	0.682925840331407	1	3587/3717/6772/9021/3716/3561/3460/6778/5777/3570/595/6776/23533/896/6773/6774/3597/1439/3572/2885/1438/1442/3459	IL10RA/JAK2/STAT1/SOCS3/JAK1/IL2RG/IFNGR2/STAT6/PTPN6/IL6R/CCND1/STAT5A/PIK3R5/CCND3/STAT2/STAT3/IL13RA1/CSF2RB/IL6ST/GRB2/CSF2RA/CSH1/IFNGR1	23
hsa00510	N-Glycan biosynthesis	7/936	49/5868	0.68491564467726	1	6185/1650/7991/2530/23193/8818/79053	RPN2/DDOST/TUSC3/FUT8/GANAB/DPM2/ALG8	7
hsa04350	TGF-beta signaling pathway	12/936	84/5868	0.707682681525238	1	7040/7124/655/3397/4052/387/3399/3400/7027/5933/3398/4090	TGFB1/TNF/BMP7/ID1/LTBP1/RHOA/ID3/ID4/TFDP1/RBL1/ID2/SMAD5	12
hsa00604	Glycosphingolipid biosynthesis - ganglio series	2/936	15/5868	0.716520955921587	1	8869/3074	ST3GAL5/HEXB	2
hsa00280	Valine, leucine and isoleucine degradation	6/936	44/5868	0.724928099363991	1	217/259307/1892/501/3033/39	ALDH2/IL4I1/ECHS1/ALDH7A1/HADH/ACAT2	6
hsa04114	Oocyte meiosis	16/936	112/5868	0.72508478198429	1	983/9126/4085/898/51529/817/11261/805/9088/6195/26271/9134/7531/818/3480/1017	CDK1/SMC3/MAD2L1/CCNE1/ANAPC11/CAMK2D/CHP1/CALM2/PKMYT1/RPS6KA1/FBXO5/CCNE2/YWHAE/CAMK2G/IGF1R/CDK2	16
hsa00512	Mucin type O-Glycan biosynthesis	4/936	30/5868	0.727819323939047	1	63917/56913/29071/374378	GALNT11/C1GALT1/C1GALT1C1/GALNT18	4
hsa00650	Butanoate metabolism	4/936	30/5868	0.727819323939047	1	1892/3033/39/5160	ECHS1/HADH/ACAT2/PDHA1	4
hsa03060	Protein export	3/936	23/5868	0.734501195585251	1	3309/9789/11231	HSPA5/SPCS2/SEC63	3
hsa05213	Endometrial cancer	7/936	52/5868	0.744959906370574	1	1956/999/595/23533/3265/2885/572	EGFR/CDH1/CCND1/PIK3R5/HRAS/GRB2/BAD	7
hsa04210	Apoptosis	12/936	87/5868	0.753084679512595	1	8743/7124/11213/3553/4792/23533/330/11261/1439/4615/572/823	TNFSF10/TNF/IRAK3/IL1B/NFKBIA/PIK3R5/BIRC3/CHP1/CSF2RB/MYD88/BAD/CAPN1	12
hsa00760	Nicotinate and nicotinamide metabolism	3/936	24/5868	0.761244402821771	1	10135/23475/4860	NAMPT/QPRT/PNP	3
hsa04977	Vitamin digestion and absorption	3/936	24/5868	0.761244402821771	1	6948/6573/80704	TCN2/SLC19A1/SLC19A3	3
hsa00040	Pentose and glucuronate interconversions	4/936	32/5868	0.774423222113624	1	217/231/51181/7360	ALDH2/AKR1B1/DCXR/UGP2	4
hsa00260	Glycine, serine and threonine metabolism	4/936	32/5868	0.774423222113624	1	10993/501/2731/6470	SDS/ALDH7A1/GLDC/SHMT1	4
hsa04020	Calcium signaling pathway	25/936	177/5868	0.779154473177577	1	6546/1956/5724/2778/292/5330/490/2185/5027/2769/10800/5579/817/3274/11261/153/8877/805/291/7416/2767/818/7419/5257/293	SLC8A1/EGFR/PTAFR/GNAS/SLC25A5/PLCB2/ATP2B1/PTK2B/P2RX7/GNA15/CYSLTR1/PRKCB/CAMK2D/HRH2/CHP1/ADRB1/SPHK1/CALM2/SLC25A4/VDAC1/GNA11/CAMK2G/VDAC3/PHKB/SLC25A6	25
hsa00360	Phenylalanine metabolism	2/936	17/5868	0.780121937821339	1	259307/9588	IL4I1/PRDX6	2
hsa00511	Other glycan degradation	2/936	17/5868	0.780121937821339	1	2517/3074	FUCA1/HEXB	2
hsa04930	Type II diabetes mellitus	6/936	48/5868	0.800019362069086	1	7124/9021/3101/3099/23533/3643	TNF/SOCS3/HK3/HK2/PIK3R5/INSR	6
hsa04720	Long-term potentiation	9/936	70/5868	0.807106122624966	1	5330/5579/817/3265/11261/805/6195/5906/818	PLCB2/PRKCB/CAMK2D/HRAS/CHP1/CALM2/RPS6KA1/RAP1A/CAMK2G	9
hsa04730	Long-term depression	9/936	70/5868	0.807106122624966	1	4067/2778/5330/5579/2771/3265/2767/2770/3480	LYN/GNAS/PLCB2/PRKCB/GNAI2/HRAS/GNA11/GNAI1/IGF1R	9
hsa04622	RIG-I-like receptor signaling pathway	9/936	71/5868	0.820343297585377	1	9636/7124/3665/3627/4792/3576/23586/1432/8653	ISG15/TNF/IRF7/CXCL10/NFKBIA/CXCL8/DDX58/MAPK14/DDX3Y	9
hsa00430	Taurine and hypotaurine metabolism	1/936	10/5868	0.824330316889714	1	1036	CDO1	1
hsa04122	Sulfur relay system	1/936	10/5868	0.824330316889714	1	4338	MOCS2	1
hsa00030	Pentose phosphate pathway	3/936	27/5868	0.828539578566181	1	2203/226/22934	FBP1/ALDOA/RPIA	3
hsa00860	Porphyrin and chlorophyll metabolism	5/936	43/5868	0.83824098587945	1	2495/2512/3162/326625/210	FTH1/FTL/HMOX1/MMAB/ALAD	5
hsa00565	Ether lipid metabolism	4/936	36/5868	0.84854377987865	1	54947/7941/56994/8613	LPCAT2/PLA2G7/CHPT1/PLPP3	4
hsa04130	SNARE interactions in vesicular transport	4/936	36/5868	0.84854377987865	1	10791/8676/8677/10228	VAMP5/STX11/STX10/STX6	4
hsa03013	RNA transport	20/936	151/5868	0.849723280103151	1	10209/26986/5901/8021/10248/3837/65110/9086/29107/55110/4116/7175/5411/9669/1983/8669/8661/1964/53371/1981	EIF1/PABPC1/RAN/NUP214/POP7/KPNB1/UPF3A/EIF1AY/NXT1/MAGOHB/MAGOH/TPR/PNN/EIF5B/EIF5/EIF3J/EIF3A/EIF1AX/NUP54/EIF4G1	20
hsa00740	Riboflavin metabolism	1/936	11/5868	0.852399081551924	1	54	ACP5	1
hsa04962	Vasopressin-regulated water reabsorption	5/936	44/5868	0.852768279022458	1	397/2778/9586/140735/1783	ARHGDIB/GNAS/CREB5/DYNLL2/DYNC1LI2	5
hsa04973	Carbohydrate digestion and absorption	5/936	44/5868	0.852768279022458	1	5330/3101/3099/23533/5579	PLCB2/HK3/HK2/PIK3R5/PRKCB	5
hsa04150	mTOR signaling pathway	6/936	52/5868	0.858202527236008	1	7422/23533/54541/6195/6009/6194	VEGFA/PIK3R5/DDIT4/RPS6KA1/RHEB/RPS6	6
hsa00340	Histidine metabolism	3/936	29/5868	0.863778320625976	1	217/501/51451	ALDH2/ALDH7A1/LCMT1	3
hsa00500	Starch and sucrose metabolism	6/936	54/5868	0.881612659585842	1	178/3101/3099/80146/7360/2548	AGL/HK3/HK2/UXS1/UGP2/GAA	6
hsa04120	Ubiquitin mediated proteolysis	17/936	135/5868	0.887011618851183	1	9246/9021/51529/672/11065/330/1642/27338/7321/6477/10055/55120/6502/27339/10075/7334/10277	UBE2L6/SOCS3/ANAPC11/BRCA1/UBE2C/BIRC3/DDB1/UBE2S/UBE2D1/SIAH1/SAE1/FANCL/SKP2/PRPF19/HUWE1/UBE2N/UBE4B	17
hsa04710	Circadian rhythm	2/936	22/5868	0.887307962750626	1	8553/79365	BHLHE40/BHLHE41	2
hsa03320	PPAR signaling pathway	8/936	70/5868	0.889809937733223	1	948/11001/4973/1622/2171/2182/2710/5468	CD36/SLC27A2/OLR1/DBI/FABP5/ACSL4/GK/PPARG	8
hsa04070	Phosphatidylinositol signaling system	9/936	78/5868	0.894310054559201	1	5330/23533/5579/805/3613/8527/3635/1040/10423	PLCB2/PIK3R5/PRKCB/CALM2/IMPA2/DGKD/INPP5D/CDS1/CDIPT	9
hsa00920	Sulfur metabolism	1/936	13/5868	0.895808753057844	1	6817	SULT1A1	1
hsa04910	Insulin signaling pathway	17/936	138/5868	0.906222979087306	1	2203/9021/3101/3099/23533/3265/805/6009/6194/2885/5792/23433/3635/572/3643/5257/51422	FBP1/SOCS3/HK3/HK2/PIK3R5/HRAS/CALM2/RHEB/RPS6/GRB2/PTPRF/RHOQ/INPP5D/BAD/INSR/PHKB/PRKAG2	17
hsa00350	Tyrosine metabolism	4/936	41/5868	0.91125409669885	1	259307/1312/128/51451	IL4I1/COMT/ADH5/LCMT1	4
hsa00603	Glycosphingolipid biosynthesis - globo series	1/936	14/5868	0.912465116360638	1	3074	HEXB	1
hsa04970	Salivary secretion	10/936	89/5868	0.920086581498931	1	4069/1471/2778/5330/490/5579/153/805/3783/6548	LYZ/CST3/GNAS/PLCB2/ATP2B1/PRKCB/ADRB1/CALM2/KCNN4/SLC9A1	10
hsa04960	Aldosterone-regulated sodium reabsorption	4/936	42/5868	0.920590467358708	1	6446/23533/5579/3643	SGK1/PIK3R5/PRKCB/INSR	4
hsa00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	2/936	25/5868	0.925851551059704	1	8733/8818	GPAA1/DPM2	2
hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/936	15/5868	0.92646112782057	1	2530	FUT8	1
hsa00053	Ascorbate and aldarate metabolism	2/936	26/5868	0.93565964158983	1	217/501	ALDH2/ALDH7A1	2
hsa00770	Pantothenate and CoA biosynthesis	1/936	16/5868	0.938221316503288	1	1806	DPYD	1
hsa00450	Selenocompound metabolism	1/936	17/5868	0.948102527670909	1	4548	MTR	1
hsa04975	Fat digestion and absorption	4/936	46/5868	0.949725648610408	1	948/10555/8613/39	CD36/AGPAT2/PLPP3/ACAT2	4
hsa00564	Glycerophospholipid metabolism	8/936	80/5868	0.954395443921447	1	54947/10555/56994/8613/8527/1040/23761/10423	LPCAT2/AGPAT2/CHPT1/PLPP3/DGKD/CDS1/PISD/CDIPT	8
hsa04744	Phototransduction	2/936	29/5868	0.95821855161039	1	409/805	ARRB2/CALM2	2
hsa04310	Wnt signaling pathway	17/936	150/5868	0.958279939485134	1	5880/5330/595/5579/817/896/11261/387/27101/4041/6477/3725/818/6907/23002/10725/5881	RAC2/PLCB2/CCND1/PRKCB/CAMK2D/CCND3/CHP1/RHOA/CACYBP/LRP5/SIAH1/JUN/CAMK2G/TBL1X/DAAM1/NFAT5/RAC3	17
hsa00600	Sphingolipid metabolism	3/936	40/5868	0.965297314478628	1	8560/8877/8613	DEGS1/SPHK1/PLPP3	3
hsa03015	mRNA surveillance pathway	8/936	83/5868	0.965662985969609	1	26986/124540/65110/29107/55110/4116/5411/8106	PABPC1/MSI2/UPF3A/NXT1/MAGOHB/MAGOH/PNN/PABPN1	8
hsa00590	Arachidonic acid metabolism	5/936	59/5868	0.969341622692329	1	2876/240/6916/4048/9536	GPX1/ALOX5/TBXAS1/LTA4H/PTGES	5
hsa01040	Biosynthesis of unsaturated fatty acids	1/936	21/5868	0.974163418350896	1	9524	TECR	1
hsa00910	Nitrogen metabolism	1/936	23/5868	0.981773865346743	1	2752	GLUL	1
hsa04964	Proximal tubule bicarbonate reclamation	1/936	23/5868	0.981773865346743	1	4190	MDH1	1
hsa00514	Other types of O-glycan biosynthesis	3/936	46/5868	0.984415991531421	1	3955/4242/283464	LFNG/MFNG/GXYLT1	3
hsa04916	Melanogenesis	9/936	101/5868	0.986809050742152	1	2778/5330/5579/817/2771/3265/805/2770/818	GNAS/PLCB2/PRKCB/CAMK2D/GNAI2/HRAS/CALM2/GNAI1/CAMK2G	9
hsa04972	Pancreatic secretion	9/936	101/5868	0.986809050742152	1	2778/5330/490/3784/5579/387/9545/5906/6548	GNAS/PLCB2/ATP2B1/KCNQ1/PRKCB/RHOA/RAB3D/RAP1A/SLC9A1	9
hsa00562	Inositol phosphate metabolism	4/936	57/5868	0.986876114788977	1	51477/5330/3613/10423	ISYNA1/PLCB2/IMPA2/CDIPT	4
hsa04950	Maturity onset diabetes of the young	1/936	25/5868	0.987144249420695	1	3087	HHEX	1
hsa02010	ABC transporters	2/936	44/5868	0.995631652954441	1	6891/6890	TAP2/TAP1	2
hsa00140	Steroid hormone biosynthesis	3/936	56/5868	0.996135289057109	1	3292/1312/412	HSD17B1/COMT/STS	3
hsa04340	Hedgehog signaling pathway	3/936	56/5868	0.996135289057109	1	4036/655/2737	LRP2/BMP7/GLI3	3
hsa04270	Vascular smooth muscle contraction	9/936	116/5868	0.997264303313714	1	2778/800/5330/5579/3779/387/805/4637/2767	GNAS/CALD1/PLCB2/PRKCB/KCNMB1/RHOA/CALM2/MYL6/GNA11	9
hsa04140	Regulation of autophagy	1/936	34/5868	0.997331863524675	1	11337	GABARAP	1
hsa00980	Metabolism of xenobiotics by cytochrome P450	4/936	71/5868	0.997926781785763	1	4259/2950/128/4257	MGST3/GSTP1/ADH5/MGST1	4
hsa04976	Bile secretion	4/936	71/5868	0.997926781785763	1	366/6513/2778/6548	AQP9/SLC2A1/GNAS/SLC9A1	4
hsa00982	Drug metabolism - cytochrome P450	4/936	73/5868	0.998422507780729	1	4259/2950/128/4257	MGST3/GSTP1/ADH5/MGST1	4
hsa04742	Taste transduction	2/936	52/5868	0.998749037974989	1	2778/5330	GNAS/PLCB2	2
hsa00830	Retinol metabolism	2/936	64/5868	0.999815701495968	1	128/216	ADH5/ALDH1A1	2
hsa05217	Basal cell carcinoma	1/936	55/5868	0.999932653904653	1	2737	GLI3	1
hsa00970	Aminoacyl-tRNA biosynthesis	1/936	63/5868	0.999983483043615	1	55699	IARS2	1
hsa04080	Neuroactive ligand-receptor interaction	20/936	272/5868	0.999995138424493	1	706/2357/728/2359/719/10161/5724/5734/8698/53829/5027/10800/3274/153/56288/5032/1442/2564/1140/1138	TSPO/FPR1/C5AR1/FPR3/C3AR1/LPAR6/PTAFR/PTGER4/S1PR4/P2RY13/P2RX7/CYSLTR1/HRH2/ADRB1/PARD3/P2RY11/CSH1/GABRE/CHRNB1/CHRNA5	20
hsa04740	Olfactory transduction	4/936	388/5868	1	1	409/817/805/818	ARRB2/CAMK2D/CALM2/CAMK2G	4