ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	Count
GO:0001819	positive regulation of cytokine production	131/2053	467/18722	4.46756006545051e-25	2.68053603927031e-21	TYROBP/FCER1G/HLA-A/AIF1/HLA-DPA1/LAPTM5/HLA-DPB1/MNDA/PTPRC/CYBB/CD14/CD74/CCL3/FCN1/SLC11A1/CYBA/ISG15/HLA-F/CSF1R/LGALS9/CLEC7A/TGFB1/CD84/GPSM3/PYCARD/C5AR1/SORL1/CD86/LY96/LILRB2/B2M/HLA-E/HAVCR2/C3AR1/LILRB1/CD83/OAS2/TLR2/POU2F2/GBP5/SCIMP/HMGB1/FGR/JAK2/MBP/LRRK2/TLR1/CD4/TNFRSF14/CASP1/IFI16/TNF/IRAK3/TLR4/HMGB2/HSPD1/IL1B/CD36/APP/STAT1/PTAFR/HMOX1/CEBPB/IRF8/IRF7/CCR2/PTGER4/RUNX1/SASH3/C3/CADM1/RPS3/LILRA2/TLR6/TLR7/CD46/HSP90AA1/SYK/NLRP3/IL27RA/SOD1/RARA/LILRA5/RSAD2/HPSE/TREM2/ADAM8/IL6R/NFAM1/IRF1/AIM2/IL16/SPN/P2RX7/HILPDA/AGPAT2/OAS1/BRCA1/IRF5/TLR8/NLRP12/FERMT1/HRAS/SULF2/SPHK1/ISL1/CCDC88B/NLRP1/STAT3/HDAC2/RGCC/PNP/IL6ST/GATA3/MYD88/IL17RA/SPTBN1/PHB/STOML2/PARK7/ARHGEF2/DDX1/HSPA1A/DDX58/BTN3A1/IFNGR1/MDK/IL18/S100A13/MAPK14/GAPDH	131
GO:0002263	cell activation involved in immune response	92/2053	279/18722	2.78687491733367e-23	7.3183691871747e-20	TYROBP/FCER1G/HLA-DRA/PTPRC/HLA-DRB1/FGL2/LGALS1/ITGB2/CD74/CORO1A/CCL3/SLC11A1/HLA-F/LCP1/SPI1/HLA-DMB/LGALS9/CLEC7A/TGFB1/NCKAP1L/CD84/PYCARD/LYN/LAT2/CD86/APBB1IP/HAVCR2/LILRB1/CD300A/RAC2/ITGAL/HMGB1/FGR/DOCK10/ITGAM/TLR4/HSPD1/APP/GAPT/PTAFR/HMOX1/IRF8/GRN/STXBP2/CCR2/PTGER4/ADGRE2/PRAM1/DOCK2/LILRA2/BTK/STAT6/CD46/SYK/NLRP3/IL27RA/RARA/UNG/LGALS3/SEMA4A/BCL6/LFNG/TREM2/IL6R/PTK2B/GPR183/SPN/ICAM1/MFNG/CX3CR1/MSH2/CD180/MSH6/IFI35/NOTCH2/STAT3/GATA3/SNX4/RPS6/MYD88/ANXA3/EIF2AK4/NFKBIZ/ERCC1/RNF8/RIF1/TFRC/DOCK11/MDK/IL18/EXO1/S100A13	92
GO:0002366	leukocyte activation involved in immune response	91/2053	275/18722	3.65918459358735e-23	7.3183691871747e-20	TYROBP/FCER1G/HLA-DRA/PTPRC/HLA-DRB1/FGL2/LGALS1/ITGB2/CD74/CORO1A/CCL3/SLC11A1/HLA-F/LCP1/SPI1/HLA-DMB/LGALS9/CLEC7A/TGFB1/NCKAP1L/CD84/PYCARD/LYN/LAT2/CD86/APBB1IP/HAVCR2/LILRB1/CD300A/RAC2/ITGAL/HMGB1/FGR/DOCK10/ITGAM/TLR4/HSPD1/GAPT/PTAFR/HMOX1/IRF8/GRN/STXBP2/CCR2/PTGER4/ADGRE2/PRAM1/DOCK2/LILRA2/BTK/STAT6/CD46/SYK/NLRP3/IL27RA/RARA/UNG/LGALS3/SEMA4A/BCL6/LFNG/TREM2/IL6R/PTK2B/GPR183/SPN/ICAM1/MFNG/CX3CR1/MSH2/CD180/MSH6/IFI35/NOTCH2/STAT3/GATA3/SNX4/RPS6/MYD88/ANXA3/EIF2AK4/NFKBIZ/ERCC1/RNF8/RIF1/TFRC/DOCK11/MDK/IL18/EXO1/S100A13	91
GO:0042110	T cell activation	128/2053	487/18722	8.96002771082043e-22	1.08954506045379e-18	FCER1G/HLA-A/AIF1/HLA-DPA1/LAPTM5/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/FGL2/LGALS1/HLA-DMA/CD74/CORO1A/MSN/SLC11A1/TNFSF13B/CD44/CD48/LCP1/TNFRSF1B/HLA-DQB1/SPI1/HLA-DMB/LGALS9/CLEC7A/HLA-DQA1/NCKAP1L/CD84/MAFB/PYCARD/LYN/WAS/ZFP36L2/CD86/LILRB2/HLA-DQA2/B2M/APBB1IP/HLA-E/HAVCR2/LILRB1/CD83/CD300A/LILRB4/RAC2/ITGAL/HMGB1/CTSL/CD4/TNFRSF14/HLA-DRB5/PRDX2/HSPD1/PAG1/SLAMF7/IL1B/CEBPB/CLEC4A/CCR2/PTGER4/RUNX1/DOCK2/SASH3/RPS3/PRKDC/CD24/GPNMB/STAT6/CD46/PREX1/DDOST/SYK/SIRPB1/NLRP3/IL27RA/TNFAIP8L2/SOD1/PTPN6/JAML/RARA/CSK/LGALS3/DPP4/SEMA4A/CD1D/IL4I1/RSAD2/BCL6/ZFP36L1/LFNG/ADAM8/IL6R/VAV1/IRF1/GPR183/SPN/ICAM1/RUNX3/PAWR/CCND3/CD151/RHOA/CCDC88B/STAT3/SOX4/MAP3K8/PNP/IL6ST/GATA3/SIRPA/DLG5/RPS6/STOML2/EIF2AK4/NFKBIZ/PSMB10/DLG1/BAD/TCIRG1/FKBP1A/BTN3A1/YES1/GLI3/TFRC/MDK/IL18/FANCA	128
GO:0022407	regulation of cell-cell adhesion	121/2053	448/18722	1.03954597152318e-21	1.08954506045379e-18	HLA-A/AIF1/HLA-DPA1/LAPTM5/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/FGL2/LGALS1/ITGB2/FXYD5/HLA-DMA/CD74/CORO1A/TNFSF13B/CD44/HLA-DQB1/SPI1/HLA-DMB/LGALS9/HLA-DQA1/TGFB1/NCKAP1L/PYCARD/LYN/PLAUR/CD9/CD86/LILRB2/HLA-DQA2/B2M/FERMT3/HLA-E/HAVCR2/LILRB1/CD83/CD300A/LILRB4/HMGB1/KLF4/SPINT2/JAK2/MBP/VEGFA/CD4/TNFRSF14/CDH1/HLA-DRB5/ALOX5/PRDX2/TNF/HSPD1/PAG1/IL1B/MYADM/ITGA4/PTAFR/CEBPB/IL1RN/CCR2/RUNX1/SASH3/RPS3/CD24/GPNMB/JAK1/CD46/SYK/SIRPB1/NLRP3/IL27RA/TNFAIP8L2/TENM3/PTPN6/RARA/CSK/BMP7/LGALS3/DPP4/CD1D/IL4I1/NOTCH1/BCL6/ADAM8/VAV1/IRF1/SH2B3/SPN/ICAM1/RUNX3/PAWR/RDX/RHOA/CCDC88B/SOX4/MAP3K8/RGCC/PNP/IL6ST/GATA3/SIRPA/DLG5/ASS1/ANK3/PLPP3/TJP1/NFKBIZ/DLG1/BAD/C1QTNF1/YES1/GLI3/TFRC/MDK/UBASH3B/PTK2/IL18/PTPRU/MAPK14/NFAT5	121
GO:0007159	leukocyte cell-cell adhesion	107/2053	371/18722	1.08954506045379e-21	1.08954506045379e-18	HLA-A/AIF1/HLA-DPA1/LAPTM5/HLA-DPB1/S100A8/HLA-DRA/PTPRC/HLA-DRB1/FGL2/LGALS1/ITGB2/HLA-DMA/CD74/CORO1A/MSN/TNFSF13B/CD44/HLA-DQB1/HLA-DMB/PECAM1/LGALS9/HLA-DQA1/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-DQA2/B2M/FERMT3/HLA-E/HAVCR2/LILRB1/CD83/CD300A/LILRB4/RAC2/ITGAL/HMGB1/KLF4/CD4/TNFRSF14/HLA-DRB5/ALOX5/PRDX2/TNF/HSPD1/PAG1/IL1B/ITGA4/PTAFR/CEBPB/CCR2/RUNX1/SASH3/OLR1/RPS3/CD24/GPNMB/SELPLG/CD46/SYK/SIRPB1/NLRP3/IL27RA/TNFAIP8L2/PTPN6/RARA/CSK/BMP7/ITGB1/LGALS3/DPP4/S100A9/CD1D/IL4I1/BCL6/ADAM8/VAV1/IRF1/SPN/ICAM1/CX3CR1/RUNX3/PAWR/RHOA/CCDC88B/SOX4/MAP3K8/PNP/IL6ST/GATA3/SIRPA/DLG5/ASS1/NFKBIZ/EZR/DLG1/BAD/SELL/YES1/GLI3/TFRC/MDK/IL18/NFAT5	107
GO:0045785	positive regulation of cell adhesion	118/2053	437/18722	3.45244876591646e-21	2.95924179935696e-18	HLA-A/AIF1/HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/LGALS1/ITGB2/HLA-DMA/CD74/CORO1A/TNFSF13B/CD44/HLA-DQB1/HLA-DMB/LGALS9/HLA-DQA1/NCKAP1L/FLNA/PYCARD/LYN/PLAUR/CD86/LILRB2/HLA-DQA2/B2M/APBB1IP/HLA-E/HAVCR2/LILRB1/CD83/LILRB4/FN1/HMGB1/JAK2/VEGFA/ITGA6/CD4/TNFRSF14/HLA-DRB5/ALOX5/TNF/HSPD1/IL1B/CD36/MYADM/P4HB/ITGA4/PTAFR/ADGRG1/CCR2/RUNX1/SASH3/RPS3/CD24/TGM2/JAK1/CD46/PREX1/SYK/SIRPB1/DAG1/NLRP3/IL27RA/PTPN6/RARA/CSK/BMP7/DPP4/CD1D/IL4I1/BCL6/CALR/ADAM8/VAV1/PTK2B/EMP2/ICAM1/RRAS/RUNX3/S100A10/LIMS1/FERMT1/PLEKHA2/C1QBP/CCDC80/NRP1/RHOA/CIB1/CCDC88B/SOX4/MAP3K8/PNP/IL6ST/GATA3/ARL2/ITGAV/SIRPA/ANK3/PLPP3/TJP1/CDK6/FERMT2/NFKBIZ/VAV3/BAD/YES1/GLI3/TFRC/STK4/MDK/PTN/TRIOBP/IL18/PTPRU/NFAT5/RAC3	118
GO:0006260	DNA replication	84/2053	260/18722	1.01962071393794e-20	7.64715535453451e-18	SAMHD1/DUT/NASP/EGFR/PCNA/MCM7/RRM1/GMNN/MCM3/MCM5/RBBP7/ORC6/RPA3/MCM6/FEN1/NUCKS1/CDK1/S100A11/SMC3/BCL6/SUPT16H/RAD51/CDC6/RFC3/MCM4/RRM2/GINS2/CCNE1/RMI2/RFC4/RFC2/SET/CCDC88A/ATAD5/DTL/NAP1L1/CHEK1/CDT1/LIG1/RBBP4/RPA2/MCM2/HRAS/RNASEH2A/MCM10/RFC1/FAM111B/CCNA2/FBXO5/CCNE2/TOPBP1/BLM/PTMS/POLD3/HMGA1/CACYBP/DSCC1/SSRP1/BRCA2/ID3/ESCO2/CHAF1A/PRIM1/POLE3/CDC45/DBF4/PNKP/STOML2/RPA1/MMS22L/WDR18/JUN/POLA1/TIPIN/POLD4/MGME1/TIMELESS/CDK2/POLQ/POLD2/PURA/NOC3L/POLE2/E2F7	84
GO:1903039	positive regulation of leukocyte cell-cell adhesion	77/2053	239/18722	5.08955673482235e-19	3.3930378232149e-16	HLA-A/AIF1/HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/LGALS1/ITGB2/HLA-DMA/CD74/CORO1A/TNFSF13B/CD44/HLA-DQB1/HLA-DMB/LGALS9/HLA-DQA1/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-DQA2/B2M/HLA-E/HAVCR2/LILRB1/CD83/LILRB4/HMGB1/CD4/TNFRSF14/HLA-DRB5/ALOX5/TNF/HSPD1/IL1B/ITGA4/PTAFR/CCR2/RUNX1/SASH3/RPS3/CD24/CD46/SYK/SIRPB1/NLRP3/IL27RA/PTPN6/RARA/CSK/DPP4/CD1D/IL4I1/BCL6/ADAM8/VAV1/ICAM1/RUNX3/RHOA/CCDC88B/SOX4/MAP3K8/PNP/IL6ST/GATA3/SIRPA/NFKBIZ/BAD/YES1/GLI3/TFRC/MDK/IL18/NFAT5	77
GO:0022409	positive regulation of cell-cell adhesion	85/2053	284/18722	1.39099569833093e-18	8.34597418998557e-16	HLA-A/AIF1/HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/LGALS1/ITGB2/HLA-DMA/CD74/CORO1A/TNFSF13B/CD44/HLA-DQB1/HLA-DMB/LGALS9/HLA-DQA1/NCKAP1L/PYCARD/LYN/PLAUR/CD86/LILRB2/HLA-DQA2/B2M/HLA-E/HAVCR2/LILRB1/CD83/LILRB4/HMGB1/JAK2/CD4/TNFRSF14/HLA-DRB5/ALOX5/TNF/HSPD1/IL1B/ITGA4/PTAFR/CCR2/RUNX1/SASH3/RPS3/CD24/JAK1/CD46/SYK/SIRPB1/NLRP3/IL27RA/PTPN6/RARA/CSK/BMP7/DPP4/CD1D/IL4I1/BCL6/ADAM8/VAV1/ICAM1/RUNX3/RHOA/CCDC88B/SOX4/MAP3K8/PNP/IL6ST/GATA3/SIRPA/ANK3/PLPP3/TJP1/NFKBIZ/BAD/YES1/GLI3/TFRC/MDK/IL18/PTPRU/NFAT5	85
GO:1903037	regulation of leukocyte cell-cell adhesion	93/2053	336/18722	1.0346916916432e-17	5.64377286350837e-15	HLA-A/AIF1/HLA-DPA1/LAPTM5/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/FGL2/LGALS1/ITGB2/HLA-DMA/CD74/CORO1A/TNFSF13B/CD44/HLA-DQB1/HLA-DMB/LGALS9/HLA-DQA1/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-DQA2/B2M/HLA-E/HAVCR2/LILRB1/CD83/CD300A/LILRB4/HMGB1/KLF4/CD4/TNFRSF14/HLA-DRB5/ALOX5/PRDX2/TNF/HSPD1/PAG1/IL1B/ITGA4/PTAFR/CEBPB/CCR2/RUNX1/SASH3/RPS3/CD24/GPNMB/CD46/SYK/SIRPB1/NLRP3/IL27RA/TNFAIP8L2/PTPN6/RARA/CSK/LGALS3/DPP4/CD1D/IL4I1/BCL6/ADAM8/VAV1/IRF1/SPN/ICAM1/RUNX3/PAWR/RHOA/CCDC88B/SOX4/MAP3K8/PNP/IL6ST/GATA3/SIRPA/DLG5/ASS1/NFKBIZ/DLG1/BAD/YES1/GLI3/TFRC/MDK/IL18/NFAT5	93
GO:0050870	positive regulation of T cell activation	69/2053	216/18722	5.77116167767345e-17	2.88558083883673e-14	HLA-A/AIF1/HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/LGALS1/HLA-DMA/CD74/CORO1A/TNFSF13B/HLA-DQB1/HLA-DMB/LGALS9/HLA-DQA1/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-DQA2/B2M/HLA-E/HAVCR2/LILRB1/CD83/LILRB4/HMGB1/CD4/TNFRSF14/HLA-DRB5/HSPD1/IL1B/CCR2/RUNX1/SASH3/RPS3/CD24/CD46/SYK/SIRPB1/NLRP3/IL27RA/PTPN6/RARA/CSK/DPP4/CD1D/IL4I1/BCL6/ADAM8/VAV1/RUNX3/RHOA/CCDC88B/SOX4/MAP3K8/PNP/IL6ST/GATA3/SIRPA/NFKBIZ/BAD/YES1/GLI3/TFRC/MDK/IL18	69
GO:0002181	cytoplasmic translation	54/2053	148/18722	2.29739556802901e-16	1.06033641601339e-13	RPS21/RPS29/RPS5/RPS17/RPS23/RPS7/RPSA/RPS27/RPS18/RPL37A/RPS3/RPL18/RPS16/RPLP0/RPS14/RPL5/RPL27A/RPL37/RPS12/RPL23/RPL7A/RPLP1/RPL23A/RPS19/RPL36/RPL28/RPL13A/RPL35/RPL3/RPL21/RPS27A/RPS15A/RPL10A/RPL31/TMA7/RPS2/RPS9/RPLP2/RPL14/RPS6/RPS8/RPL7/RPL15/EIF5/EIF3J/DENR/EIF3A/RPS20/RPS4X/RPS25/DRG1/RPL8/EIF4G1/EIF3L	54
GO:0070661	leukocyte proliferation	87/2053	318/18722	2.57232756449871e-16	1.10242609907088e-13	TYROBP/HLA-A/AIF1/HLA-DPA1/HLA-DPB1/LST1/MNDA/PTPRC/HLA-DRB1/CD74/CORO1A/BST2/MSN/SLC11A1/TNFSF13B/TNFRSF1B/CSF1R/HLA-DMB/LGALS9/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-E/HAVCR2/MEF2C/LILRB1/CD300A/LILRB4/RAC2/HMGB1/TNFRSF14/PRDX2/TNFAIP3/TLR4/HELLS/HSPD1/IL1B/GSTP1/GAPT/CEBPB/CCR2/DOCK2/SASH3/RPS3/CD24/BTK/GPNMB/CD46/SYK/IL27RA/PTPN6/LGALS3/CD1D/IL4I1/HHEX/BCL6/TREM2/IRF1/GPR183/SPN/SLC39A10/CD180/PAWR/CCND3/CD151/CCDC88B/PNP/IL6ST/DLG5/RPS6/MYD88/IMPDH2/PSMB10/INPP5D/VAV3/DLG1/CDKN1A/TCIRG1/BTN3A1/TFRC/PTK2/IL18/PURA/PKN1/CD320	87
GO:0002683	negative regulation of immune system process	107/2053	434/18722	2.99327361624656e-16	1.19730944649862e-13	HLA-B/TYROBP/HLA-A/LAPTM5/LST1/CD68/MNDA/PTPRC/HLA-DRB1/FGL2/CD74/CCL3/BST2/ISG15/HLA-F/TSC22D3/SPI1/LGALS9/TGFB1/SAMHD1/NCKAP1L/CD84/MAFB/LYN/CD86/LILRB2/HLA-E/HAVCR2/LILRB1/LILRB3/CD300A/HCK/LILRB4/DUSP1/HMGB1/TMEM176B/GPX1/FGR/TNFRSF14/FBN1/PRDX2/IFI16/TNF/TNFAIP3/IRAK3/TLR4/PAG1/TMEM176A/GBP1/HMOX1/CEBPB/CD300LF/GRN/CCR2/PTGER4/ARRB2/RUNX1/PRKDC/BTK/GPNMB/STAT6/CD46/SYK/IL27RA/TNFAIP8L2/PTPN6/RARA/LGALS3/DPP4/IL4I1/SAMSN1/BCL6/TREM2/CD59/IRF1/SPN/OAS1/RHBDF2/CX3CR1/RUNX3/RPS19/NLRC5/PAWR/C1QBP/TRIB1/STAT2/USP15/RIN3/DLG5/CDK6/INPP5D/PHPT1/EZR/DLG1/PARP14/YES1/GLI3/ID2/MDK/NME1/PLK2/UBASH3B/HSPA9/PKN1/MAPK14/SERPING1/PPARG	107
GO:0032103	positive regulation of response to external stimulus	105/2053	427/18722	6.91523814303858e-16	2.59321430363947e-13	TYROBP/AIF1/S100A8/TMSB4X/MNDA/CD74/CXCR4/CCL3/FCN1/CYBA/HLA-F/CSF1R/SPI1/CCL4/LGALS9/CLEC7A/TGFB1/NCKAP1L/FLNA/GPSM3/PYCARD/C5AR1/LYN/LY96/HLA-E/HAVCR2/C3AR1/TLR2/S100A12/HCK/RAC2/GBP5/SCIMP/HMGB1/LY86/EGFR/ALOX5AP/JAK2/LRRK2/VEGFA/NEAT1/OASL/CCR1/IFI16/TNF/TLR4/HMGB2/HSPD1/IL1B/APP/CEBPB/GRN/IRF7/CCR2/PTGER4/CXCL10/C3/CADM1/PRKDC/LILRA2/BTK/TGM2/MET/TLR7/NFKBIA/HSP90AA1/SYK/CAMK1D/LILRA5/S100A9/CD1D/PARP9/CALR/TREM2/PLA2G7/ADAM8/IL6R/VAV1/PTK2B/AIM2/IL16/CX3CR1/TLR8/CXCL8/NLRP12/TPBG/RPS19/CD180/NLRC5/C1QBP/NRP1/IFI35/USP15/IL6ST/SNX4/PLSCR1/IL17RA/XRCC5/NFKBIZ/XRCC6/PARK7/MDK/PTN/PTK2/IL18	105
GO:0002274	myeloid leukocyte activation	68/2053	223/18722	1.37924969057995e-15	4.86794008439982e-13	TYROBP/FCER1G/AIF1/PTPRC/ITGB2/CD74/CCL3/SLC11A1/SPI1/LGALS9/CD84/PYCARD/C5AR1/LYN/LAT2/HAVCR2/TLR2/CD300A/S100A12/LILRB4/RAC2/HMGB1/FGR/JAK2/LRRK2/TLR1/ITGAM/TNF/TLR4/HSPD1/APP/PTAFR/HMOX1/NAMPT/LCP2/CD300LF/GRN/STXBP2/CCR2/ADGRE2/PRAM1/DOCK2/LILRA2/BTK/TLR6/IFNGR2/PREX1/SYK/CD93/TREM2/C1QA/HAMP/CD33/CX3CR1/CXCL8/SPHK1/IFI35/NOTCH2/SNX4/MYD88/PLSCR1/ANXA3/KMT2E/IFNGR1/IL18/NDRG1/S100A13/ITGB8	68
GO:0050867	positive regulation of cell activation	103/2053	420/18722	1.59497371145194e-15	5.31657903817315e-13	TYROBP/HLA-A/AIF1/HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/LGALS1/ITGB2/HLA-DMA/CD74/CORO1A/CCL3/TNFSF13B/PLEK/HLA-F/HLA-DQB1/HLA-DMB/LGALS9/CLEC7A/HLA-DQA1/TGFB1/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-DQA2/B2M/HLA-E/HAVCR2/MEF2C/LILRB1/CD83/LILRB4/HMGB1/FGR/JAK2/LRRK2/ITGAM/CD4/TNFRSF14/HLA-DRB5/TLR4/HSPD1/IL1B/PTAFR/CCR2/RUNX1/SASH3/RPS3/PRKDC/CD24/LILRA2/BTK/TLR6/STAT6/CD46/SYK/SIRPB1/NLRP3/IL27RA/PTPN6/RARA/CSK/LILRA5/DPP4/CD1D/IL4I1/BCL6/TREM2/ADAM8/VAV1/GPR183/HAMP/SLC39A10/MSH2/RUNX3/RHOA/CCDC88B/RPS6KA1/SOX4/MAP3K8/PNP/IL6ST/GATA3/SNX4/SIRPA/MYD88/NFKBIZ/XRCC6/INPP5D/VAV3/BAD/CDKN1A/YES1/GLI3/RIF1/TFRC/MDK/IL18/CD320	103
GO:0002697	regulation of immune effector process	89/2053	339/18722	1.80611735128741e-15	5.70352847774973e-13	HLA-B/TYROBP/HLA-A/LAPTM5/HLA-DRA/PTPRC/HLA-DRB1/FGL2/ITGB2/CD74/BST2/HLA-F/NCF1/TNFRSF1B/SPI1/HLA-DMB/LGALS9/CLEC7A/TGFB1/NCKAP1L/CD84/LYN/WAS/CD86/B2M/HLA-E/HAVCR2/LILRB1/CD300A/LILRB4/RAC2/SCIMP/HMGB1/FGR/ITGAM/TNFRSF14/TNF/IRAK3/TLR4/HSPD1/IL1B/CD36/PTAFR/HMOX1/GRN/STXBP2/CCR2/ARRB2/ADGRE2/PRAM1/SASH3/C3/CADM1/PRKDC/BTK/STAT6/CD46/SYK/NLRP3/IL27RA/PTPN6/RARA/LGALS3/CD1D/IL4I1/RSAD2/BCL6/TREM2/VAV1/CD59/ICAM1/PHB2/CX3CR1/MSH2/RPS19/C1QBP/GATA3/SNX4/RAP1A/PHB/NFKBIZ/DDX1/DDX58/RIF1/TFRC/IL18/PKN1/DNAJB9/SERPING1	89
GO:0002237	response to molecule of bacterial origin	93/2053	363/18722	2.17861049944075e-15	6.45151619094423e-13	VIM/S100A8/TSPO/CD68/CD14/CCL3/SLC11A1/TNFRSF1B/ZFP36/SPI1/LGALS9/TGFB1/MTDH/PYCARD/C5AR1/LYN/CD86/LY96/LILRB2/B2M/HAVCR2/MEF2C/LILRB1/IL10RA/TLR2/HCK/SCIMP/HMGB1/LY86/FOS/SOD2/JAK2/TLR1/PRDX2/CASP1/TNF/TNFAIP3/IRAK3/TLR4/HMGB2/HSPD1/IL1B/CD36/GSTP1/PTAFR/CEBPB/IRF8/PTGER4/CXCL10/CD24/LILRA2/TLR6/NFKBIA/NLRP3/CARD16/RARA/LITAF/S100A9/NOTCH1/TREM2/NR4A1/COMT/HAMP/ICAM1/ADH5/IRF5/GJA1/CX3CR1/CXCL8/HPGD/CD180/TRIB1/RHOA/GNG12/HDAC2/MAPKAPK3/CSF2RB/PRDX3/CDK4/SIRPA/ASS1/MYD88/MGST1/ACP5/HNRNPA0/JUN/GCH1/PTGES/PABPN1/PRPF8/IL18/MAPK14/ALAD	93
GO:0050900	leukocyte migration	94/2053	369/18722	2.25803066683048e-15	6.45151619094423e-13	FCER1G/AIF1/S100A8/CCL3L3/ITGB2/CD74/CXCR4/CORO1A/CCL3/MSN/CSF1R/SPI1/CCL4/PECAM1/LGALS9/NCKAP1L/GPSM3/PYCARD/C5AR1/LYN/CD9/C3AR1/CD300A/S100A12/HCK/DUSP1/RAC2/MYO1G/ITGAL/HMGB1/VEGFA/TNFRSF14/ALOX5/CCR1/TNF/TREM1/CXCL16/APP/ITGA4/PTAFR/HMOX1/CCR2/PTGER4/ADGRE2/CXCL10/SELPLG/PREX1/SYK/CAMK1D/NLRP3/IL27RA/BSG/JAML/LYST/ITGB1/PPIA/LGALS3/DPP4/S100A9/PPIB/CALR/TREM2/PLA2G7/ADAM8/IL6R/VAV1/PTK2B/GPR183/IL16/SPN/ICAM1/FLT1/CX3CR1/CXCL8/NLRP12/RPS19/C1QBP/TRPM2/RHOA/RIN3/GATA3/SIRPA/JAM3/MYD88/RHOG/EPS8/SBDS/VAV3/SELL/MPP1/YES1/MDK/PTN/PTK2	94
GO:0050863	regulation of T cell activation	87/2053	329/18722	2.36569644604009e-15	6.45189939829116e-13	HLA-A/AIF1/HLA-DPA1/LAPTM5/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/FGL2/LGALS1/HLA-DMA/CD74/CORO1A/TNFSF13B/TNFRSF1B/HLA-DQB1/HLA-DMB/LGALS9/HLA-DQA1/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-DQA2/B2M/HLA-E/HAVCR2/LILRB1/CD83/CD300A/LILRB4/RAC2/HMGB1/CD4/TNFRSF14/HLA-DRB5/PRDX2/HSPD1/PAG1/IL1B/CEBPB/CCR2/RUNX1/SASH3/RPS3/CD24/GPNMB/CD46/SYK/SIRPB1/NLRP3/IL27RA/TNFAIP8L2/SOD1/PTPN6/RARA/CSK/LGALS3/DPP4/CD1D/IL4I1/BCL6/ADAM8/VAV1/IRF1/SPN/RUNX3/PAWR/RHOA/CCDC88B/SOX4/MAP3K8/PNP/IL6ST/GATA3/SIRPA/DLG5/NFKBIZ/DLG1/BAD/YES1/GLI3/TFRC/MDK/IL18/FANCA	87
GO:1903706	regulation of hemopoiesis	93/2053	367/18722	4.52363758457252e-15	1.18007936988848e-12	HLA-B/TYROBP/HLA-DRA/PTPRC/HLA-DRB1/FGL2/CD74/EVI2B/CCL3/ISG15/ZFP36/SPI1/LGALS9/TGFB1/NCKAP1L/MAFB/LYN/ZFP36L2/CD86/LILRB2/B2M/MEF2C/LILRB1/LILRB3/CD83/LILRB4/HMGB1/TMEM176B/FOS/CD4/FBN1/PRDX2/CCR1/TNF/TLR4/HMGB2/TMEM176A/STAT1/CEBPB/IRF7/CCR2/RUNX1/SASH3/PRKDC/BTK/CD46/NFKBIA/SYK/NLRP3/SOD1/PTPN6/RARA/IL4I1/BCL6/ZFP36L1/TREM2/ADAM8/NFAM1/PTK2B/IRF1/RUNX3/TRIB1/RHOA/FAM210B/CIB1/NOTCH2/STAT3/SOX4/PNP/GATA3/SCIN/CDK6/PITHD1/NFKBIZ/XRCC6/RASSF2/HCLS1/JUN/INPP5D/HSPA1A/BAD/GLI3/ID2/MDK/NME1/UBASH3B/PTN/HSPA9/IL18/MAPK14/RCOR1/FANCA/MEIS2	93
GO:0046651	lymphocyte proliferation	79/2053	288/18722	5.24708002395638e-15	1.31177000598909e-12	TYROBP/HLA-A/AIF1/HLA-DPA1/HLA-DPB1/LST1/MNDA/PTPRC/HLA-DRB1/CD74/CORO1A/MSN/SLC11A1/TNFSF13B/TNFRSF1B/HLA-DMB/LGALS9/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-E/HAVCR2/MEF2C/LILRB1/CD300A/LILRB4/RAC2/HMGB1/TNFRSF14/PRDX2/TLR4/HELLS/HSPD1/IL1B/GAPT/CEBPB/CCR2/DOCK2/SASH3/RPS3/CD24/BTK/GPNMB/CD46/SYK/IL27RA/PTPN6/LGALS3/CD1D/IL4I1/BCL6/IRF1/GPR183/SPN/SLC39A10/CD180/PAWR/CCND3/CD151/CCDC88B/PNP/IL6ST/DLG5/RPS6/MYD88/IMPDH2/PSMB10/INPP5D/VAV3/DLG1/CDKN1A/BTN3A1/TFRC/IL18/PURA/PKN1/CD320	79
GO:0002443	leukocyte mediated immunity	105/2053	440/18722	5.99777961378518e-15	1.43946710730844e-12	HLA-B/TYROBP/FCER1G/HLA-A/HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/ITGB2/HLA-DMA/CD74/CORO1A/CCL3/BST2/HLA-F/TNFRSF1B/HLA-DQB1/SPI1/HLA-DMB/LGALS9/CLEC7A/HLA-DQA1/TGFB1/NCKAP1L/CD84/LYN/WAS/LAT2/HLA-DQA2/B2M/HLA-E/HAVCR2/LILRB1/CD300A/LILRB4/RAC2/MYO1G/SCIMP/HMGB1/FGR/ITGAM/TUBB/HLA-DRB5/TNF/TLR4/TREM1/HSPD1/SLAMF7/IL1B/GAPT/PTAFR/HMOX1/IRF7/STXBP2/CCR2/ARRB2/ADGRE2/PRAM1/SASH3/C3/CADM1/BTK/CTSH/STAT6/CD46/SYK/NLRP3/IL27RA/PTPN6/LYST/UNG/TUBB4B/CD1D/IL4I1/RSAD2/BCL6/TREM2/C1QA/VAV1/EMP2/ICAM1/CX3CR1/MSH2/TLR8/C1QBP/MSH6/GATA3/SNX4/MYD88/PRDX1/ANXA3/INPP5D/KMT2E/DDX1/ERCC1/TCIRG1/DDX58/RNF8/RIF1/TFRC/IL18/EXO1/S100A13/SERPING1	105
GO:0002285	lymphocyte activation involved in immune response	61/2053	194/18722	8.37816495089105e-15	1.93342268097486e-12	FCER1G/HLA-DRA/PTPRC/HLA-DRB1/FGL2/LGALS1/CD74/CORO1A/SLC11A1/HLA-F/LCP1/SPI1/HLA-DMB/LGALS9/TGFB1/NCKAP1L/CD86/APBB1IP/HAVCR2/LILRB1/ITGAL/HMGB1/DOCK10/TLR4/HSPD1/GAPT/IRF8/PTGER4/STAT6/CD46/NLRP3/IL27RA/RARA/UNG/LGALS3/SEMA4A/BCL6/LFNG/IL6R/PTK2B/GPR183/SPN/ICAM1/MFNG/MSH2/CD180/MSH6/NOTCH2/STAT3/GATA3/RPS6/EIF2AK4/NFKBIZ/ERCC1/RNF8/RIF1/TFRC/DOCK11/MDK/IL18/EXO1	61
GO:0032943	mononuclear cell proliferation	79/2053	291/18722	9.76163315943577e-15	2.16925181320795e-12	TYROBP/HLA-A/AIF1/HLA-DPA1/HLA-DPB1/LST1/MNDA/PTPRC/HLA-DRB1/CD74/CORO1A/MSN/SLC11A1/TNFSF13B/TNFRSF1B/HLA-DMB/LGALS9/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-E/HAVCR2/MEF2C/LILRB1/CD300A/LILRB4/RAC2/HMGB1/TNFRSF14/PRDX2/TLR4/HELLS/HSPD1/IL1B/GAPT/CEBPB/CCR2/DOCK2/SASH3/RPS3/CD24/BTK/GPNMB/CD46/SYK/IL27RA/PTPN6/LGALS3/CD1D/IL4I1/BCL6/IRF1/GPR183/SPN/SLC39A10/CD180/PAWR/CCND3/CD151/CCDC88B/PNP/IL6ST/DLG5/RPS6/MYD88/IMPDH2/PSMB10/INPP5D/VAV3/DLG1/CDKN1A/BTN3A1/TFRC/IL18/PURA/PKN1/CD320	79
GO:0032496	response to lipopolysaccharide	88/2053	343/18722	1.13913864790303e-14	2.42423082980433e-12	VIM/S100A8/TSPO/CD68/CD14/CCL3/SLC11A1/TNFRSF1B/ZFP36/SPI1/LGALS9/TGFB1/MTDH/PYCARD/C5AR1/LYN/CD86/LY96/LILRB2/HAVCR2/MEF2C/LILRB1/IL10RA/TLR2/HCK/SCIMP/HMGB1/LY86/FOS/SOD2/JAK2/PRDX2/CASP1/TNF/TNFAIP3/IRAK3/TLR4/HMGB2/HSPD1/IL1B/CD36/GSTP1/PTAFR/CEBPB/IRF8/PTGER4/CXCL10/LILRA2/NFKBIA/NLRP3/CARD16/RARA/LITAF/S100A9/NOTCH1/TREM2/NR4A1/COMT/HAMP/ICAM1/ADH5/GJA1/CX3CR1/CXCL8/HPGD/CD180/TRIB1/RHOA/GNG12/HDAC2/MAPKAPK3/CSF2RB/PRDX3/CDK4/SIRPA/ASS1/MYD88/MGST1/ACP5/HNRNPA0/JUN/GCH1/PTGES/PABPN1/PRPF8/IL18/MAPK14/ALAD	88
GO:1903131	mononuclear cell differentiation	102/2053	426/18722	1.17171156773876e-14	2.42423082980433e-12	HLA-B/FCER1G/HLA-DRA/PTPRC/HLA-DRB1/FGL2/LGALS1/CD74/TNFSF13B/CSF1R/SPI1/LGALS9/NCKAP1L/MAFB/LYN/ZFP36L2/CD86/LILRB2/B2M/LILRB1/CD83/LILRB4/HMGB1/TMEM176B/KLF6/LYL1/VEGFA/DOCK10/CTSL/CD4/PRDX2/IFI16/IL1B/TMEM176A/ITGA4/CEBPB/IRF8/IRF7/CCR2/PTGER4/RUNX1/DOCK2/SASH3/PRKDC/BTK/STAT6/CD46/PREX1/SYK/NLRP3/SOD1/PTPN6/RARA/SLC25A5/ITGB1/SEMA4A/CD1D/IL4I1/HHEX/RSAD2/BCL6/ZFP36L1/LFNG/TREM2/IKZF1/ADAM8/IL6R/VAV1/NFAM1/PTK2B/IRF1/GPR183/SPN/MFNG/EZH2/MSH2/RUNX3/TRPM2/RHOA/NOTCH2/STAT3/SOX4/PNP/GATA3/PBX1/RPS6/CDK6/NFKBIZ/XRCC6/JUN/INPP5D/BAD/TCIRG1/GLI3/ID2/DOCK11/MDK/IL18/DNAJB9/ITGB8/FANCA/PPARG	102
GO:0007346	regulation of mitotic cell cycle	107/2053	457/18722	1.28860800645323e-14	2.57721601290647e-12	AIF1/TGFB1/ZFP36L2/DUSP1/KLF4/EGFR/TNF/BTG3/IL1B/APP/PRKDC/PLK3/RPA3/GPNMB/CLSPN/MKI67/PTPN6/CDK1/BMP7/TIMP2/CKS1B/CENPF/ZWINT/NUSAP1/BCL6/ZFP36L1/MAD2L1/PSME2/CDC6/CCND1/CTDSPL/ANAPC11/BRCA1/PHB2/BTG2/WEE1/CDKN1C/EZH2/NAE1/MSH2/DTL/UBE2C/CHEK1/BTG1/ADAMTS1/CDT1/RPA2/RAD51C/CCND3/DDB1/RDX/CKS2/SPHK1/TRIAP1/CDCA5/PKMYT1/FBXO5/RAD21/TOPBP1/BLM/SOX4/BRD7/RGCC/AURKAIP1/CDK4/BRD4/PBX1/GTSE1/LRP5/SDCBP/BUB3/ANLN/BRCA2/KIF20B/TPR/FANCD2/TFDP1/NDC80/OBSL1/YWHAE/USP22/FOXO4/TIPIN/APEX1/RBL1/TTK/KMT2E/DLG1/CDKN1A/CDK2AP2/CDK2/AURKB/LCMT1/ID2/CHMP4C/FOXC1/INSR/PTPN3/PLK2/E2F1/BRCC3/BUB1B/EIF4G1/MDC1/E2F7/KNTC1/MEIS2	107
GO:0030099	myeloid cell differentiation	94/2053	381/18722	1.89288991844944e-14	3.66365790667633e-12	TYROBP/HLA-DRB1/CD74/EVI2B/CCL3/ISG15/ZFP36/CSF1R/SPI1/TGFB1/NCKAP1L/MAFB/LYN/B2M/MEF2C/LILRB1/LILRB3/TLR2/LILRB4/HMGB1/FOS/JUNB/JAK2/VEGFA/SNX10/CD4/FBN1/KLF2/OSCAR/CCR1/IFI16/TNF/TLR4/HMGB2/PARP1/APP/STAT1/CEBPB/IRF8/IRF7/RUNX1/PRKDC/NFKBIA/RPS14/PTPN6/RARA/SLC25A5/BCL6/ZFP36L1/TREM2/IKZF1/FLI1/PTK2B/SH2B3/GPR183/GAB3/RPS19/NBEAL2/EPAS1/TRIB1/FAM210B/CIB1/NOTCH2/STAT3/PRDX3/GATA3/RPS6/SCIN/CDK6/PITHD1/WASF2/RASSF2/HCLS1/JUN/INPP5D/KMT2E/HSPA1A/EIF2AK1/TCIRG1/ID2/TFRC/TGFBR3/NME1/UBASH3B/SMAD5/HSPA9/ITGB8/MAPK14/RCOR1/PPARG/GPC3/MEIS2/NCAPG2/GLO1	94
GO:0070663	regulation of leukocyte proliferation	70/2053	245/18722	2.06938139948122e-14	3.88009012402728e-12	TYROBP/HLA-A/AIF1/HLA-DPA1/HLA-DPB1/LST1/MNDA/PTPRC/HLA-DRB1/CD74/CORO1A/BST2/TNFSF13B/TNFRSF1B/CSF1R/HLA-DMB/LGALS9/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-E/HAVCR2/MEF2C/LILRB1/CD300A/LILRB4/RAC2/HMGB1/TNFRSF14/TNFAIP3/TLR4/IL1B/GSTP1/CEBPB/CCR2/SASH3/RPS3/CD24/BTK/GPNMB/CD46/SYK/IL27RA/PTPN6/LGALS3/CD1D/IL4I1/HHEX/BCL6/IRF1/GPR183/SPN/SLC39A10/PAWR/CCDC88B/PNP/IL6ST/DLG5/MYD88/INPP5D/VAV3/DLG1/CDKN1A/TFRC/PTK2/IL18/PKN1/CD320	70
GO:0048002	antigen processing and presentation of peptide antigen	31/2053	62/18722	2.1484665266625e-14	3.90630277575001e-12	HLA-B/FCER1G/HLA-A/HLA-DPA1/CTSS/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/CD74/HLA-C/SLC11A1/IFI30/HLA-F/HLA-DQB1/HLA-DMB/HLA-DQA1/PYCARD/HLA-DQA2/B2M/HLA-E/CTSL/HLA-DRB5/TAP2/CLEC4A/TAP1/CTSD/CALR/TREM2/CTSV/TAPBP	31
GO:0002703	regulation of leukocyte mediated immunity	66/2053	226/18722	3.65809271346455e-14	6.41278302235835e-12	HLA-B/TYROBP/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/ITGB2/BST2/HLA-F/TNFRSF1B/SPI1/LGALS9/CLEC7A/TGFB1/NCKAP1L/CD84/LYN/WAS/B2M/HLA-E/HAVCR2/LILRB1/CD300A/LILRB4/RAC2/SCIMP/HMGB1/FGR/ITGAM/TNF/TLR4/HSPD1/IL1B/PTAFR/HMOX1/STXBP2/CCR2/ARRB2/ADGRE2/PRAM1/SASH3/C3/CADM1/BTK/STAT6/CD46/SYK/NLRP3/IL27RA/PTPN6/CD1D/IL4I1/RSAD2/BCL6/TREM2/VAV1/ICAM1/CX3CR1/MSH2/GATA3/SNX4/DDX1/DDX58/RIF1/TFRC/IL18	66
GO:0002696	positive regulation of leukocyte activation	98/2053	409/18722	3.74079009637571e-14	6.41278302235835e-12	TYROBP/HLA-A/AIF1/HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/LGALS1/ITGB2/HLA-DMA/CD74/CORO1A/CCL3/TNFSF13B/HLA-F/HLA-DQB1/HLA-DMB/LGALS9/CLEC7A/HLA-DQA1/TGFB1/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-DQA2/B2M/HLA-E/HAVCR2/MEF2C/LILRB1/CD83/LILRB4/HMGB1/FGR/LRRK2/ITGAM/CD4/TNFRSF14/HLA-DRB5/TLR4/HSPD1/IL1B/PTAFR/CCR2/RUNX1/SASH3/RPS3/PRKDC/CD24/BTK/TLR6/STAT6/CD46/SYK/SIRPB1/NLRP3/IL27RA/PTPN6/RARA/CSK/DPP4/CD1D/IL4I1/BCL6/TREM2/ADAM8/VAV1/GPR183/HAMP/SLC39A10/MSH2/RUNX3/RHOA/CCDC88B/SOX4/MAP3K8/PNP/IL6ST/GATA3/SNX4/SIRPA/MYD88/NFKBIZ/XRCC6/INPP5D/VAV3/BAD/CDKN1A/YES1/GLI3/RIF1/TFRC/MDK/IL18/CD320	98
GO:0006261	DNA-dependent DNA replication	51/2053	151/18722	5.60750368156725e-14	9.34583946927876e-12	SAMHD1/PCNA/MCM7/GMNN/MCM3/MCM5/ORC6/MCM6/FEN1/NUCKS1/BCL6/RAD51/CDC6/RFC3/MCM4/CCNE1/RFC4/RFC2/CDT1/LIG1/MCM2/MCM10/RFC1/FBXO5/CCNE2/TOPBP1/BLM/POLD3/HMGA1/DSCC1/BRCA2/PRIM1/POLE3/CDC45/DBF4/PNKP/STOML2/RPA1/MMS22L/WDR18/POLA1/TIPIN/POLD4/MGME1/TIMELESS/POLQ/POLD2/PURA/NOC3L/POLE2/E2F7	51
GO:0048872	homeostasis of number of cells	74/2053	272/18722	6.08565434549494e-14	9.86862866837018e-12	CD74/CORO1A/TNFSF13B/ISG15/TSC22D3/ZFP36/SPI1/LGALS9/NCKAP1L/MAFB/LYN/B2M/MEF2C/HMGB1/SKIL/JAK2/VEGFA/DOCK10/KLF2/PRDX2/TNFAIP3/HMGB2/STAT1/GAPT/HMOX1/RPS17/ADGRG1/CCR2/SASH3/PRKDC/SOD1/RPS14/SLC25A5/NOTCH1/BCL6/ZFP36L1/IKZF1/SH2B3/GPR183/HAMP/FSTL1/EZH2/CX3CR1/RPS19/PMAIP1/EPAS1/FAM210B/STAT3/SOX4/GATA3/FH/RPS6/JAM3/LIPA/LGR4/PRDX1/CDK6/RASSF2/HCLS1/INPP5D/KMT2E/HSPA1A/TCIRG1/ID2/DOCK11/TGFBR3/SMAD5/HSPA9/PKN1/MAPK14/ASXL1/RCOR1/RAC3/NCAPG2	74
GO:0045930	negative regulation of mitotic cell cycle	67/2053	235/18722	8.37165320233035e-14	1.32183997931532e-11	TGFB1/ZFP36L2/DUSP1/KLF4/EGFR/TNF/BTG3/PRKDC/PLK3/GPNMB/CLSPN/CDK1/BMP7/TIMP2/CENPF/ZWINT/BCL6/ZFP36L1/MAD2L1/CDC6/CCND1/CTDSPL/BRCA1/BTG2/WEE1/CDKN1C/EZH2/NAE1/MSH2/DTL/CHEK1/BTG1/CDT1/RPA2/TRIAP1/FBXO5/RAD21/TOPBP1/BLM/SOX4/BRD7/RGCC/AURKAIP1/GTSE1/BUB3/TPR/FANCD2/NDC80/FOXO4/TIPIN/RBL1/TTK/DLG1/CDKN1A/CDK2AP2/CDK2/AURKB/LCMT1/CHMP4C/FOXC1/PTPN3/PLK2/BRCC3/BUB1B/MDC1/E2F7/KNTC1	67
GO:0045786	negative regulation of cell cycle	93/2053	385/18722	1.0142014291746e-13	1.56030989103784e-11	TGFB1/ZFP36L2/LILRB1/DUSP1/KLF4/EGFR/TNF/TNFAIP3/BTG3/GMNN/PRKDC/PLK3/GPNMB/CLSPN/CDK1/BMP7/TIMP2/CENPF/ZWINT/HHEX/NR2F2/BCL6/ZFP36L1/NPM1/MAD2L1/NR4A1/CDC6/CCND1/CTDSPL/BRCA1/BTG2/WEE1/CDKN1C/EZH2/NAE1/MSH2/DTL/RUNX3/CHEK1/BTG1/CDT1/HPGD/RPA2/TRIAP1/FBXO5/RAD21/TOPBP1/BLM/SOX4/FBXO6/BRD7/RGCC/AURKAIP1/GATA3/WDR76/ATF5/GTSE1/BUB3/TPR/FANCD2/CDC45/CDK6/CDKN2A/NDC80/EIF2AK4/FOXO4/TIPIN/RBL1/TTK/DLG1/CDKN1A/IPO5/TIMELESS/IPO7/CDK2AP2/RHOB/CDK2/AURKB/LCMT1/CHMP4C/FOXC1/PTPN3/PLK2/PRPF19/CCP110/E2F1/BRCC3/BUB1B/TP53I13/MAPK14/MDC1/E2F7/KNTC1	93
GO:0002764	immune response-regulating signaling pathway	106/2053	468/18722	1.71098313432403e-13	2.56647470148604e-11	TYROBP/FCER1G/HLA-A/LAPTM5/CTSS/HLA-DPB1/MNDA/PTPRC/HLA-DRB1/CD14/FCN1/CYBA/FPR1/HLA-DQB1/CLEC7A/NCKAP1L/C5AR1/LYN/FPR3/LAT2/LY96/LILRB2/PIK3AP1/HAVCR2/MEF2C/C3AR1/LILRB1/TLR2/CD300A/HCK/LILRB4/MYO1G/SCIMP/HMGB1/THEMIS2/FGR/TLR1/CLEC4E/OASL/FCGR1B/TNFAIP3/IRAK3/TLR4/COLEC12/HSPD1/CD36/GBP1/LCP2/CD300LF/IRF7/ARRB2/PRAM1/RPS3/CD24/LILRA2/BTK/TLR6/CTSH/TLR7/NFKBIA/SYK/PTPN6/CSK/LGALS3/RSAD2/TREM2/VAV1/NFAM1/IRF1/CD33/SLC39A10/CMTM3/OAS1/PRKCB/PHB2/SLC15A3/TLR8/BIRC3/PAWR/C1QBP/HRAS/IFI35/UNC93B1/USP15/MAPKAPK3/GATA3/MYD88/LGR4/PLSCR1/KCNN4/RAP1A/PHB/STOML2/NFKBIZ/BCAR1/INPP5D/PHPT1/EZR/VAV3/HSPA1A/DDX58/BTN3A1/YES1/PTK2/UBE2N/PLEKHA1	106
GO:0071706	tumor necrosis factor superfamily cytokine production	57/2053	186/18722	2.15517204941904e-13	3.07881721345577e-11	TYROBP/TSPO/PTPRC/CYBB/CD14/CCL3/CYBA/ZFP36/LGALS9/CLEC7A/CD84/PYCARD/CD86/LY96/HLA-E/HAVCR2/LILRB1/OAS2/TLR2/HMGB1/JAK2/LRRK2/TLR1/TNFAIP3/IRAK3/TLR4/HSPD1/CD36/GSTP1/APP/PTAFR/CLEC4A/CCR2/ARRB2/SASH3/LILRA2/GPNMB/SYK/IL27RA/PTPN6/RARA/LILRA5/TREM2/ADAM8/SPN/CD33/OAS1/CX3CR1/ISL1/STAT3/HDAC2/SIRPA/MYD88/ACP5/ARHGEF2/DDX58/IFNGR1	57
GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	57/2053	186/18722	2.15517204941904e-13	3.07881721345577e-11	TYROBP/TSPO/PTPRC/CYBB/CD14/CCL3/CYBA/ZFP36/LGALS9/CLEC7A/CD84/PYCARD/CD86/LY96/HLA-E/HAVCR2/LILRB1/OAS2/TLR2/HMGB1/JAK2/LRRK2/TLR1/TNFAIP3/IRAK3/TLR4/HSPD1/CD36/GSTP1/APP/PTAFR/CLEC4A/CCR2/ARRB2/SASH3/LILRA2/GPNMB/SYK/IL27RA/PTPN6/RARA/LILRA5/TREM2/ADAM8/SPN/CD33/OAS1/CX3CR1/ISL1/STAT3/HDAC2/SIRPA/MYD88/ACP5/ARHGEF2/DDX58/IFNGR1	57
GO:0002478	antigen processing and presentation of exogenous peptide antigen	23/2053	38/18722	2.22692847599181e-13	3.10734205952346e-11	FCER1G/HLA-A/HLA-DPA1/CTSS/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/CD74/IFI30/HLA-F/HLA-DQB1/HLA-DMB/HLA-DQA1/HLA-DQA2/B2M/HLA-E/CTSL/HLA-DRB5/CLEC4A/TAP1/CTSD/CTSV	23
GO:0009615	response to virus	89/2053	367/18722	2.72888156389251e-13	3.7212021325807e-11	PTPRC/FGL2/CXCR4/BST2/IFITM2/APOBEC3A/ISG15/IFI44L/CCL4/LGALS9/MX1/SAMHD1/PYCARD/LILRB1/IFI44/OAS2/TRIM22/IFIT2/TLR2/POU2F2/NPC2/IFITM3/FGR/STMN1/MX2/OASL/IFIT1/IFI16/TNF/TNFAIP3/IRAK3/GBP1/STAT1/ISG20/IFIT3/IRF7/RNASE6/CXCL10/TLR7/IFNGR2/HSP90AA1/ITGAX/LYST/IFI6/PARP9/RSAD2/IRF1/AIM2/OAS1/IFI27/IRF5/DDIT4/BNIP3L/PHB2/TLR8/BIRC3/APOBEC3G/PMAIP1/NLRC5/C1QBP/APOBEC3C/STAT2/UNC93B1/NLRP1/USP15/RPS15A/POLR3K/HMGA1/GATA3/MYD88/PLSCR1/IL17RA/CDK6/NCBP3/PHB/DTX3L/EIF2AK4/AP1S1/DDX1/DDX58/BNIP3/HERC5/IFNGR1/SKP2/AKAP1/CFL1/ITGB8/MAPK14/URI1	89
GO:0051251	positive regulation of lymphocyte activation	88/2053	362/18722	3.21358420932904e-13	4.28477894577206e-11	TYROBP/HLA-A/AIF1/HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/LGALS1/HLA-DMA/CD74/CORO1A/TNFSF13B/HLA-F/HLA-DQB1/HLA-DMB/LGALS9/CLEC7A/HLA-DQA1/TGFB1/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-DQA2/B2M/HLA-E/HAVCR2/MEF2C/LILRB1/CD83/LILRB4/HMGB1/CD4/TNFRSF14/HLA-DRB5/TLR4/HSPD1/IL1B/CCR2/RUNX1/SASH3/RPS3/PRKDC/CD24/BTK/STAT6/CD46/SYK/SIRPB1/NLRP3/IL27RA/PTPN6/RARA/CSK/DPP4/CD1D/IL4I1/BCL6/ADAM8/VAV1/GPR183/SLC39A10/MSH2/RUNX3/RHOA/CCDC88B/SOX4/MAP3K8/PNP/IL6ST/GATA3/SIRPA/MYD88/NFKBIZ/XRCC6/INPP5D/VAV3/BAD/CDKN1A/YES1/GLI3/RIF1/TFRC/MDK/IL18/CD320	88
GO:0050670	regulation of lymphocyte proliferation	64/2053	225/18722	3.3816107844807e-13	4.41079667540961e-11	TYROBP/HLA-A/AIF1/HLA-DPA1/HLA-DPB1/LST1/MNDA/PTPRC/HLA-DRB1/CD74/CORO1A/TNFSF13B/TNFRSF1B/HLA-DMB/LGALS9/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-E/HAVCR2/MEF2C/LILRB1/CD300A/LILRB4/RAC2/HMGB1/TNFRSF14/TLR4/IL1B/CEBPB/CCR2/SASH3/RPS3/CD24/BTK/GPNMB/CD46/SYK/IL27RA/PTPN6/LGALS3/CD1D/IL4I1/BCL6/IRF1/GPR183/SPN/SLC39A10/PAWR/CCDC88B/PNP/IL6ST/DLG5/MYD88/INPP5D/VAV3/DLG1/CDKN1A/TFRC/IL18/PKN1/CD320	64
GO:0019058	viral life cycle	80/2053	317/18722	4.7669830249247e-13	6.04729852328791e-11	HLA-DRB1/LGALS1/CD74/CXCR4/FCN1/BST2/IFITM2/APOBEC3A/ISG15/LGALS9/MX1/CD86/OAS2/TRIM22/CTSB/IFITM3/EGFR/ITGA5/CTSL/CD4/TNFRSF14/OASL/IFIT1/CLEC5A/HACD3/IFI16/TNF/P4HB/ISG20/SIVA1/DEK/RPSA/SELPLG/PABPC1/CD46/TOP2A/HSP90AB1/DAG1/BSG/NUCKS1/CIITA/CDK1/ITGB1/PPIA/DPP4/NOTCH1/PPIB/RSAD2/ICAM1/SIGLEC1/OAS1/IFI27/CXCL8/HSPA8/APOBEC3G/APOBEC3C/DDB1/NRP1/STAU1/ITGB5/SLC1A5/ANPEP/ITGAV/PLSCR1/TRIM38/PHB/HTATSF1/SRPK1/EIF2AK4/SLC52A1/HSPA1A/TOP2B/ATG16L2/TFRC/CHMP4C/TRIM28/VCP/EEA1/SLC3A2/DYNLT1	80
GO:0019882	antigen processing and presentation	40/2053	106/18722	4.83783881863033e-13	6.04729852328791e-11	HLA-B/FCER1G/HLA-A/HLA-DPA1/CTSS/HLA-DPB1/HLA-DRA/CD68/HLA-DRB1/FGL2/HLA-DMA/CD74/HLA-C/SLC11A1/IFI30/HLA-F/HLA-DQB1/HLA-DMB/PSMB8/HLA-DQA1/PYCARD/WAS/RAB32/LILRB2/HLA-DQA2/B2M/HLA-E/CTSL/HLA-DRB5/TAP2/CLEC4A/TAP1/CTSH/CTSD/CD1D/CALR/TREM2/ICAM1/CTSV/TAPBP	40
GO:0032944	regulation of mononuclear cell proliferation	64/2053	227/18722	5.26029051627449e-13	6.44117206074427e-11	TYROBP/HLA-A/AIF1/HLA-DPA1/HLA-DPB1/LST1/MNDA/PTPRC/HLA-DRB1/CD74/CORO1A/TNFSF13B/TNFRSF1B/HLA-DMB/LGALS9/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-E/HAVCR2/MEF2C/LILRB1/CD300A/LILRB4/RAC2/HMGB1/TNFRSF14/TLR4/IL1B/CEBPB/CCR2/SASH3/RPS3/CD24/BTK/GPNMB/CD46/SYK/IL27RA/PTPN6/LGALS3/CD1D/IL4I1/BCL6/IRF1/GPR183/SPN/SLC39A10/PAWR/CCDC88B/PNP/IL6ST/DLG5/MYD88/INPP5D/VAV3/DLG1/CDKN1A/TFRC/IL18/PKN1/CD320	64
GO:0031349	positive regulation of defense response	73/2053	278/18722	6.18184368902772e-13	7.41821242683327e-11	TYROBP/S100A8/MNDA/CCL3/FCN1/CYBA/HLA-F/SPI1/CLEC7A/GPSM3/PYCARD/LYN/HLA-E/HAVCR2/MEF2C/TLR2/S100A12/HCK/GBP5/HMGB1/EGFR/ALOX5AP/JAK2/LRRK2/NEAT1/IFI16/TNF/TLR4/HMGB2/HSPD1/IL1B/APP/CEBPB/GRN/IRF7/CCR2/PTGER4/C3/CADM1/PRKDC/LILRA2/BTK/TGM2/TLR7/NFKBIA/HSP90AA1/SYK/LILRA5/S100A9/CD1D/PARP9/TREM2/PLA2G7/ADAM8/VAV1/AIM2/IL16/GJA1/TLR8/NLRP12/RPS19/NLRC5/IFI35/IL6ST/SNX4/PLSCR1/IL17RA/XRCC5/NFKBIZ/XRCC6/PARK7/MDK/IL18	73
GO:0016032	viral process	96/2053	415/18722	6.5162475260931e-13	7.66617356010953e-11	HLA-DRB1/LGALS1/CD74/CXCR4/CCL3/FCN1/BST2/IFITM2/APOBEC3A/ISG15/ZFP36/CCL4/LGALS9/MX1/CD86/OAS2/TRIM22/CTSB/IFITM3/EGFR/ITGA5/CTSL/CD4/TNFRSF14/OASL/IFIT1/CLEC5A/HACD3/IFI16/TNF/P4HB/STAT1/ISG20/SIVA1/DEK/IRF7/RPSA/SELPLG/PABPC1/CD46/TOP2A/RAN/HSP90AB1/DAG1/BSG/NUCKS1/CIITA/CDK1/ITGB1/PPIA/DPP4/NOTCH1/PARP9/PPIB/RSAD2/ICAM1/SIGLEC1/OAS1/IFI27/PHB2/PSMC3/CXCL8/HSPA8/APOBEC3G/APOBEC3C/DDB1/NRP1/STAU1/ITGB5/SLC1A5/ANPEP/ITGAV/PLSCR1/FUT8/TRIM38/PHB/HTATSF1/SRPK1/EIF2AK4/JUN/SLC52A1/HSPA1A/TOP2B/ATG16L2/DENR/TFRC/CHMP4C/INSR/TRIM28/EIF3A/VCP/CFL1/EIF3L/EEA1/SLC3A2/DYNLT1	96
GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	40/2053	107/18722	6.91567874823867e-13	7.96953842083079e-11	TYROBP/PTPRC/CYBB/CD14/CCL3/CYBA/LGALS9/CLEC7A/CD84/PYCARD/CD86/LY96/HLA-E/HAVCR2/OAS2/TLR2/HMGB1/JAK2/LRRK2/TLR1/TLR4/HSPD1/CD36/APP/PTAFR/CCR2/SASH3/LILRA2/SYK/LILRA5/ADAM8/SPN/OAS1/ISL1/STAT3/HDAC2/MYD88/ARHGEF2/DDX58/IFNGR1	40
GO:0032635	interleukin-6 production	52/2053	165/18722	7.17258457874771e-13	7.96953842083079e-11	HLA-B/TYROBP/AIF1/CD74/CYBA/LGALS9/CLEC7A/NCKAP1L/CD84/PYCARD/LILRB2/HAVCR2/TLR2/POU2F2/LILRB4/SCIMP/HMGB1/MBP/TLR1/KLF2/TNF/TNFAIP3/IRAK3/TLR4/HSPD1/IL1B/CD36/APP/PTAFR/CEBPB/ARRB2/LILRA2/TLR6/TLR7/SYK/IL27RA/PTPN6/CSK/LILRA5/TREM2/IL6R/IL16/TLR8/NLRP12/ISL1/STAT3/SIRPA/MYD88/IL17RA/INPP5D/ARHGEF2/DDX58	52
GO:0032675	regulation of interleukin-6 production	52/2053	165/18722	7.17258457874771e-13	7.96953842083079e-11	HLA-B/TYROBP/AIF1/CD74/CYBA/LGALS9/CLEC7A/NCKAP1L/CD84/PYCARD/LILRB2/HAVCR2/TLR2/POU2F2/LILRB4/SCIMP/HMGB1/MBP/TLR1/KLF2/TNF/TNFAIP3/IRAK3/TLR4/HSPD1/IL1B/CD36/APP/PTAFR/CEBPB/ARRB2/LILRA2/TLR6/TLR7/SYK/IL27RA/PTPN6/CSK/LILRA5/TREM2/IL6R/IL16/TLR8/NLRP12/ISL1/STAT3/SIRPA/MYD88/IL17RA/INPP5D/ARHGEF2/DDX58	52
GO:1902105	regulation of leukocyte differentiation	73/2053	279/18722	7.49173263397484e-13	8.17279923706347e-11	HLA-B/TYROBP/HLA-DRA/PTPRC/HLA-DRB1/FGL2/CD74/EVI2B/CCL3/LGALS9/TGFB1/NCKAP1L/MAFB/LYN/ZFP36L2/CD86/LILRB2/LILRB1/LILRB3/CD83/LILRB4/HMGB1/TMEM176B/FOS/CD4/FBN1/PRDX2/CCR1/TNF/TLR4/TMEM176A/CEBPB/IRF7/CCR2/RUNX1/SASH3/PRKDC/BTK/CD46/SYK/NLRP3/SOD1/PTPN6/RARA/IL4I1/BCL6/ZFP36L1/TREM2/ADAM8/NFAM1/IRF1/RUNX3/TRIB1/RHOA/NOTCH2/SOX4/PNP/GATA3/CDK6/NFKBIZ/XRCC6/RASSF2/HCLS1/JUN/INPP5D/BAD/GLI3/ID2/MDK/NME1/UBASH3B/IL18/FANCA	73
GO:0032640	tumor necrosis factor production	55/2053	181/18722	8.33135448408293e-13	8.76984682535045e-11	TYROBP/TSPO/PTPRC/CYBB/CD14/CCL3/CYBA/ZFP36/LGALS9/CLEC7A/CD84/PYCARD/LY96/HLA-E/HAVCR2/LILRB1/OAS2/TLR2/HMGB1/JAK2/LRRK2/TLR1/TNFAIP3/IRAK3/TLR4/HSPD1/CD36/GSTP1/APP/PTAFR/CLEC4A/CCR2/ARRB2/SASH3/LILRA2/GPNMB/SYK/IL27RA/PTPN6/RARA/LILRA5/TREM2/SPN/CD33/OAS1/CX3CR1/ISL1/STAT3/HDAC2/SIRPA/MYD88/ACP5/ARHGEF2/DDX58/IFNGR1	55
GO:0032680	regulation of tumor necrosis factor production	55/2053	181/18722	8.33135448408293e-13	8.76984682535045e-11	TYROBP/TSPO/PTPRC/CYBB/CD14/CCL3/CYBA/ZFP36/LGALS9/CLEC7A/CD84/PYCARD/LY96/HLA-E/HAVCR2/LILRB1/OAS2/TLR2/HMGB1/JAK2/LRRK2/TLR1/TNFAIP3/IRAK3/TLR4/HSPD1/CD36/GSTP1/APP/PTAFR/CLEC4A/CCR2/ARRB2/SASH3/LILRA2/GPNMB/SYK/IL27RA/PTPN6/RARA/LILRA5/TREM2/SPN/CD33/OAS1/CX3CR1/ISL1/STAT3/HDAC2/SIRPA/MYD88/ACP5/ARHGEF2/DDX58/IFNGR1	55
GO:0034341	response to interferon-gamma	47/2053	141/18722	9.34576645478515e-13	9.66803426357084e-11	AIF1/HLA-DPA1/VIM/CCL3L3/CD74/CCL3/BST2/IFITM2/SLC11A1/CCL4/LGALS9/GBP4/GBP2/WAS/TLR2/HCK/GBP5/IFITM3/JAK2/CASP1/TLR4/CXCL16/GBP1/STAT1/IRF8/KYNU/JAK1/IFNGR2/HSP90AB1/CIITA/PARP9/IRF1/ICAM1/RPL13A/NLRC5/ACTR2/ZYX/SIRPA/MYO1C/ASS1/ACTR3/SP100/GCH1/PARP14/IFNGR1/GAPDH/PPARG	47
GO:0060326	cell chemotaxis	78/2053	310/18722	1.10210928226823e-12	1.12078910061176e-10	FCER1G/AIF1/S100A8/TMSB4X/CCL3L3/ITGB2/CD74/CXCR4/CORO1A/CCL3/CSF1R/SPI1/CCL4/LGALS9/NCKAP1L/GPSM3/C5AR1/LYN/C3AR1/S100A12/DUSP1/RAC2/HMGB1/VEGFA/ALOX5/CCR1/TREM1/HMGB2/CXCL16/GSTP1/DOCK4/CCR2/ARRB2/ADGRE2/CXCL10/MET/PREX1/SYK/CAMK1D/BSG/JAML/LYST/PPIA/LGALS3/DPP4/S100A9/CCRL2/NOTCH1/PPIB/CALR/PLA2G7/ADAM8/IL6R/VAV1/PTK2B/NR4A1/GPR183/IL16/FLT1/CX3CR1/HBEGF/CXCL8/TPBG/RPS19/C1QBP/TRPM2/NRP1/RIN3/JAM3/RHOG/BCAR1/SBDS/VAV3/MPP1/GAB1/MDK/PTN/PTK2	78
GO:0019221	cytokine-mediated signaling pathway	104/2053	472/18722	1.78912256700598e-12	1.78912256700598e-10	FCER1G/LAPTM5/TMSB4X/PTPRC/CCL3L3/CD74/CXCR4/CCL3/IFITM2/TNFSF13B/CD44/ISG15/TNFRSF1B/CSF1R/SPI1/CCL4/MX1/SAMHD1/PYCARD/LILRB2/LILRB1/LILRB3/IL10RA/OAS2/PLP2/HCK/LILRB4/IFITM3/JAK2/CD4/TNFRSF14/OASL/CCR1/CASP1/TNF/TNFAIP3/IRAK3/IL1B/GSTP1/P4HB/STAT1/IL1RN/CD300LF/IRF7/CCR2/CXCL10/CD24/LILRA2/JAK1/KRT18/IL2RG/IFNGR2/STAT6/NFKBIA/SYK/HSP90AB1/IL27RA/CARD16/PTPN6/LILRA6/LILRA5/CCRL2/NOTCH1/PARP9/TREM2/IL6R/PTK2B/IRF1/AIM2/SH2B3/STAT5A/AGPAT2/OAS1/IFI27/IRF5/CX3CR1/CXCL8/KRT8/BIRC3/LIMS1/NLRC5/SPHK1/STAT2/CIB1/STAT3/IL13RA1/CSF2RB/IL6ST/DOK1/MYD88/IL17RA/YAP1/CSF2RA/SP100/COMMD7/HSPA1A/PARP14/BAD/IFNGR1/FOXC1/RPS6KA5/IL18/ACTN4/PPARG	104
GO:0044772	mitotic cell cycle phase transition	96/2053	424/18722	2.47948225783471e-12	2.43883500770627e-10	AIF1/ZFP36L2/NASP/DUSP1/KLF4/EGFR/APP/PRKDC/PLK3/GPNMB/CLSPN/PTPN6/CDK1/ITGB1/CENPF/ZWINT/ZFP36L1/MAD2L1/PSME2/CDC6/CCND1/CCNE1/CTDSPL/ANAPC11/BRCA1/PHB2/WEE1/EZH2/NAE1/DTL/UBE2C/CHEK1/ADAMTS1/CDT1/RPA2/RAD51C/CCND3/DDB1/RDX/CKS2/TRIAP1/CDCA5/CALM2/CCNA2/PKMYT1/FBXO5/RAD21/CCNE2/UBE2S/TOPBP1/BLM/SOX4/BRD7/RGCC/CDK4/BRD4/PBX1/GTSE1/RPS6/BUB3/ANLN/TPR/CDK6/CDKN2A/DBF4/TFDP1/NDC80/BACH1/FOXO4/EPS8/APEX1/RBL1/TTK/MASTL/KMT2E/DLG1/CCNI/CDKN1A/CDK2AP2/CDK2/ENSA/AURKB/LCMT1/ID2/SKP2/CHMP4C/RBBP8/PLK2/FOXM1/E2F1/BRCC3/BUB1B/PPAT/EIF4G1/E2F7/KNTC1	96
GO:0071216	cellular response to biotic stimulus	66/2053	246/18722	2.76886916421238e-12	2.6795508040765e-10	VIM/TXNIP/TSPO/CD68/CD14/CCL3/TNFRSF1B/ZFP36/SPI1/CLEC7A/TGFB1/MTDH/PYCARD/LYN/CD86/LY96/LILRB2/HAVCR2/MEF2C/LILRB1/TLR2/HCK/SCIMP/HMGB1/LY86/TLR1/PRDX2/CASP1/TNF/TNFAIP3/TLR4/HMGB2/IL1B/CD36/GSTP1/PTAFR/CEBPB/IRF8/CXCL10/LILRA2/BTK/TLR6/NFKBIA/SYK/NLRP3/CARD16/RARA/LITAF/CCDC47/TREM2/HSPA5/HAMP/ICAM1/CX3CR1/CXCL8/CD180/TRIB1/RHOA/CDK4/SIRPA/ASS1/MYD88/PABPN1/PRPF8/IL18/MAPK14	66
GO:0002699	positive regulation of immune effector process	64/2053	235/18722	2.87923278162784e-12	2.74212645869318e-10	HLA-B/TYROBP/HLA-A/LAPTM5/HLA-DRA/PTPRC/HLA-DRB1/ITGB2/CD74/HLA-F/SPI1/HLA-DMB/LGALS9/CLEC7A/TGFB1/CD84/LYN/CD86/B2M/HLA-E/LILRB1/CD300A/RAC2/SCIMP/FGR/ITGAM/TNFRSF14/TNF/TLR4/HSPD1/IL1B/CD36/PTAFR/HMOX1/STXBP2/CCR2/ADGRE2/SASH3/C3/CADM1/BTK/STAT6/CD46/SYK/NLRP3/RARA/CD1D/RSAD2/TREM2/VAV1/PHB2/MSH2/RPS19/GATA3/SNX4/RAP1A/PHB/NFKBIZ/DDX1/DDX58/RIF1/TFRC/IL18/DNAJB9	64
GO:0030595	leukocyte chemotaxis	63/2053	230/18722	3.2331632661296e-12	3.0310905619965e-10	FCER1G/AIF1/S100A8/CCL3L3/ITGB2/CD74/CXCR4/CORO1A/CCL3/CSF1R/SPI1/CCL4/LGALS9/NCKAP1L/GPSM3/C5AR1/LYN/C3AR1/S100A12/DUSP1/RAC2/HMGB1/VEGFA/ALOX5/CCR1/TREM1/CXCL16/CCR2/ADGRE2/CXCL10/PREX1/SYK/CAMK1D/BSG/JAML/LYST/PPIA/LGALS3/DPP4/S100A9/PPIB/CALR/PLA2G7/ADAM8/IL6R/VAV1/PTK2B/GPR183/IL16/FLT1/CX3CR1/CXCL8/RPS19/C1QBP/TRPM2/RIN3/JAM3/SBDS/VAV3/MPP1/MDK/PTN/PTK2	63
GO:0007229	integrin-mediated signaling pathway	39/2053	107/18722	3.38674862480585e-12	3.12622949982079e-10	TIMP1/ITGB2/PLEK/ISG15/FLNA/FERMT3/HCK/FN1/ITGAL/FGR/ITGAM/ITGA5/ITGA6/ITGA4/PRAM1/SYK/ITGAX/LAMA5/ITGB1/ITGB4/VAV1/PTK2B/EMP2/ADAMTS1/LIMS1/FERMT1/NRP1/ITGB5/ZYX/ITGAV/PLPP3/CD63/FUT8/FERMT2/BCAR1/VAV3/PTN/PTK2/ITGB8	39
GO:0032760	positive regulation of tumor necrosis factor production	38/2053	103/18722	4.15681493749082e-12	3.7789226704462e-10	TYROBP/PTPRC/CYBB/CD14/CCL3/CYBA/LGALS9/CLEC7A/CD84/PYCARD/LY96/HLA-E/HAVCR2/OAS2/TLR2/HMGB1/JAK2/LRRK2/TLR1/TLR4/HSPD1/CD36/APP/PTAFR/CCR2/SASH3/LILRA2/SYK/LILRA5/SPN/OAS1/ISL1/STAT3/HDAC2/MYD88/ARHGEF2/DDX58/IFNGR1	38
GO:0002819	regulation of adaptive immune response	54/2053	183/18722	4.87037534040194e-12	4.36153015558382e-10	HLA-B/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/SLC11A1/TNFSF13B/CD48/HLA-F/TNFRSF1B/CLEC7A/TGFB1/NCKAP1L/PYCARD/WAS/B2M/HLA-E/HAVCR2/MEF2C/LILRB1/LILRB4/HMGB1/CD4/TNFRSF14/TNF/TNFAIP3/HSPD1/IL1B/IRF7/CCR2/SASH3/C3/BTK/STAT6/CD46/NLRP3/IL27RA/PTPN6/CD1D/IL4I1/SAMSN1/RSAD2/BCL6/TREM2/IRF1/MSH2/IL6ST/GATA3/EIF2AK4/NFKBIZ/RIF1/TFRC/IL18/PKN1	54
GO:0032732	positive regulation of interleukin-1 production	31/2053	73/18722	5.30389515763846e-12	4.67990749203394e-10	TYROBP/MNDA/CCL3/LGALS9/CLEC7A/PYCARD/HAVCR2/GBP5/HMGB1/JAK2/CASP1/IFI16/TNF/TLR4/CD36/APP/LILRA2/TLR6/NLRP3/LILRA5/AIM2/IL16/P2RX7/TLR8/NLRP12/ISL1/NLRP1/STAT3/HDAC2/MYD88/S100A13	31
GO:0002831	regulation of response to biotic stimulus	79/2053	327/18722	7.35893477204156e-12	6.39907371481875e-10	HLA-B/TYROBP/HLA-A/MNDA/HLA-DRB1/FGL2/FCN1/CYBA/ISG15/HLA-F/NCF1/SPI1/LGALS9/CLEC7A/SAMHD1/PYCARD/LYN/LY96/HLA-E/HAVCR2/LILRB1/HCK/GBP5/SCIMP/HMGB1/LY86/FGR/OASL/IFIT1/PRDX2/IFI16/TNFAIP3/IRAK3/TLR4/HMGB2/HSPD1/CD36/STAT1/GRN/IRF7/ARRB2/CADM1/PRKDC/LILRA2/HSP90AA1/SYK/HSP90AB1/CARD16/PTPN6/CD1D/IL4I1/PARP9/TREM2/ADAM8/VAV1/IRF1/AIM2/OAS1/TLR8/RPS19/BIRC3/APOBEC3G/CD180/NLRC5/C1QBP/TRIB1/STAT2/IFI35/USP15/PLSCR1/XRCC5/DTX3L/EIF2AK4/XRCC6/PARP14/DDX58/HERC5/SERPING1/PPARG	79
GO:1901990	regulation of mitotic cell cycle phase transition	74/2053	299/18722	9.89352583133896e-12	8.4689561408769e-10	AIF1/ZFP36L2/DUSP1/KLF4/EGFR/APP/PRKDC/PLK3/GPNMB/CLSPN/PTPN6/CDK1/CENPF/ZWINT/ZFP36L1/MAD2L1/PSME2/CDC6/CCND1/CTDSPL/ANAPC11/BRCA1/PHB2/WEE1/EZH2/NAE1/DTL/UBE2C/CHEK1/ADAMTS1/CDT1/RPA2/RAD51C/CCND3/DDB1/RDX/TRIAP1/CDCA5/FBXO5/RAD21/TOPBP1/BLM/SOX4/BRD7/RGCC/CDK4/BRD4/PBX1/GTSE1/BUB3/ANLN/TPR/TFDP1/NDC80/FOXO4/APEX1/RBL1/TTK/KMT2E/DLG1/CDKN1A/CDK2AP2/CDK2/AURKB/LCMT1/ID2/CHMP4C/PLK2/E2F1/BRCC3/BUB1B/EIF4G1/E2F7/KNTC1	74
GO:1901987	regulation of cell cycle phase transition	89/2053	390/18722	1.00215981000377e-11	8.4689561408769e-10	AIF1/ZFP36L2/DUSP1/KLF4/EGFR/APP/PRKDC/PLK3/GPNMB/CLSPN/PTPN6/CDK1/CENPF/ZWINT/ZFP36L1/NPM1/MAD2L1/PSME2/CDC6/CCND1/CTDSPL/ANAPC11/BRCA1/PHB2/WEE1/EZH2/ATAD5/NAE1/MSH2/DTL/UBE2C/CHEK1/ADAMTS1/CDT1/RPA2/RAD51C/CCND3/DDB1/RDX/TRIAP1/CDCA5/FBXO5/RAD21/TOPBP1/BLM/SOX4/FBXO6/BRD7/RGCC/WDR76/ATF5/CDK4/BRD4/PBX1/GTSE1/BUB3/ANLN/TPR/FANCD2/CDC45/DBF4/TFDP1/NDC80/EIF2AK4/FOXO4/TIPIN/APEX1/RBL1/TTK/KMT2E/DLG1/CDKN1A/TIMELESS/CDK2AP2/CDK2/AURKB/LCMT1/ID2/CHMP4C/PLK2/PRPF19/E2F1/BRCC3/BUB1B/EIF4G1/MAPK14/MDC1/E2F7/KNTC1	89
GO:0019884	antigen processing and presentation of exogenous antigen	24/2053	47/18722	1.04512641831329e-11	8.70938681927741e-10	FCER1G/HLA-A/HLA-DPA1/CTSS/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/CD74/IFI30/HLA-F/HLA-DQB1/HLA-DMB/HLA-DQA1/HLA-DQA2/B2M/HLA-E/CTSL/HLA-DRB5/CLEC4A/TAP1/CTSD/CD1D/CTSV	24
GO:0051607	defense response to virus	68/2053	265/18722	1.19493467248817e-11	9.68865950666083e-10	PTPRC/FGL2/BST2/IFITM2/APOBEC3A/ISG15/IFI44L/MX1/SAMHD1/PYCARD/LILRB1/OAS2/TRIM22/IFIT2/TLR2/IFITM3/MX2/OASL/IFIT1/IFI16/TNFAIP3/GBP1/STAT1/ISG20/IFIT3/IRF7/RNASE6/CXCL10/TLR7/IFNGR2/HSP90AA1/ITGAX/LYST/IFI6/PARP9/RSAD2/IRF1/AIM2/OAS1/IFI27/IRF5/DDIT4/BNIP3L/PHB2/TLR8/BIRC3/APOBEC3G/PMAIP1/NLRC5/C1QBP/APOBEC3C/STAT2/UNC93B1/NLRP1/USP15/POLR3K/MYD88/PLSCR1/NCBP3/PHB/DTX3L/EIF2AK4/DDX1/DDX58/BNIP3/HERC5/SKP2/AKAP1	68
GO:0140546	defense response to symbiont	68/2053	265/18722	1.19493467248817e-11	9.68865950666083e-10	PTPRC/FGL2/BST2/IFITM2/APOBEC3A/ISG15/IFI44L/MX1/SAMHD1/PYCARD/LILRB1/OAS2/TRIM22/IFIT2/TLR2/IFITM3/MX2/OASL/IFIT1/IFI16/TNFAIP3/GBP1/STAT1/ISG20/IFIT3/IRF7/RNASE6/CXCL10/TLR7/IFNGR2/HSP90AA1/ITGAX/LYST/IFI6/PARP9/RSAD2/IRF1/AIM2/OAS1/IFI27/IRF5/DDIT4/BNIP3L/PHB2/TLR8/BIRC3/APOBEC3G/PMAIP1/NLRC5/C1QBP/APOBEC3C/STAT2/UNC93B1/NLRP1/USP15/POLR3K/MYD88/PLSCR1/NCBP3/PHB/DTX3L/EIF2AK4/DDX1/DDX58/BNIP3/HERC5/SKP2/AKAP1	68
GO:0050727	regulation of inflammatory response	88/2053	386/18722	1.38703652884219e-11	1.10962922307375e-09	S100A8/TMSB4X/PTPRC/HLA-DRB1/CCL3/NCF1/TNFRSF1B/ZFP36/GPSM3/PYCARD/LYN/PIK3AP1/HLA-E/TLR2/S100A12/HCK/GPX1/KLF4/EGFR/ALOX5AP/FGR/JAK2/LRRK2/NEAT1/ALOX5/CASP1/TNF/AOAH/TNFAIP3/TLR4/METRNL/HSPD1/IL1B/SERPINF1/GSTP1/APP/CEBPB/GRN/CCR2/PTGER4/C3/SOCS3/BTK/TGM2/TLR7/NFKBIA/SYK/NLRP3/TNFAIP8L2/SOD1/LILRA5/S100A9/SIGLEC10/BCL6/TREM2/PLA2G7/ADAM8/IL16/HAMP/RHBDF2/NLRP12/PBK/RPS19/BIRC3/SPHK1/ISL1/IFI35/NLRP1/IL6ST/GATA3/SNX4/ZYX/BRD4/SIRPA/MYD88/IL17RA/ACP5/NFKBIZ/PARK7/PTGES/YES1/MGLL/MDK/PLK2/IL18/MAPK14/FANCA/PPARG	88
GO:0030098	lymphocyte differentiation	86/2053	374/18722	1.46784358404552e-11	1.1588238821412e-09	FCER1G/HLA-DRA/PTPRC/HLA-DRB1/FGL2/LGALS1/CD74/TNFSF13B/SPI1/LGALS9/NCKAP1L/MAFB/ZFP36L2/CD86/LILRB2/B2M/CD83/LILRB4/HMGB1/KLF6/LYL1/DOCK10/CTSL/CD4/PRDX2/IL1B/ITGA4/IRF8/CCR2/PTGER4/RUNX1/DOCK2/SASH3/PRKDC/BTK/STAT6/CD46/PREX1/SYK/NLRP3/SOD1/PTPN6/RARA/SLC25A5/ITGB1/SEMA4A/CD1D/IL4I1/HHEX/RSAD2/BCL6/ZFP36L1/LFNG/IKZF1/ADAM8/IL6R/VAV1/NFAM1/PTK2B/IRF1/GPR183/SPN/MFNG/EZH2/MSH2/RUNX3/RHOA/NOTCH2/STAT3/SOX4/PNP/GATA3/PBX1/RPS6/NFKBIZ/XRCC6/INPP5D/BAD/TCIRG1/GLI3/ID2/DOCK11/MDK/IL18/DNAJB9/FANCA	86
GO:0032755	positive regulation of interleukin-6 production	35/2053	93/18722	1.50193446236136e-11	1.17033854209976e-09	TYROBP/AIF1/CD74/CYBA/LGALS9/CLEC7A/PYCARD/LILRB2/TLR2/POU2F2/SCIMP/HMGB1/MBP/TLR1/TNF/TLR4/HSPD1/IL1B/CD36/APP/PTAFR/LILRA2/TLR6/TLR7/SYK/LILRA5/IL6R/IL16/TLR8/ISL1/STAT3/MYD88/IL17RA/ARHGEF2/DDX58	35
GO:0071219	cellular response to molecule of bacterial origin	60/2053	221/18722	1.58296150910895e-11	1.21766269931458e-09	VIM/TSPO/CD68/CD14/CCL3/TNFRSF1B/ZFP36/SPI1/TGFB1/MTDH/PYCARD/LYN/CD86/LY96/LILRB2/HAVCR2/MEF2C/LILRB1/TLR2/HCK/SCIMP/HMGB1/LY86/TLR1/PRDX2/CASP1/TNF/TNFAIP3/TLR4/HMGB2/IL1B/CD36/GSTP1/PTAFR/CEBPB/IRF8/CXCL10/LILRA2/TLR6/NFKBIA/NLRP3/CARD16/RARA/LITAF/TREM2/HAMP/ICAM1/CX3CR1/CXCL8/CD180/TRIB1/RHOA/CDK4/SIRPA/ASS1/MYD88/PABPN1/PRPF8/IL18/MAPK14	60
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	20/2053	34/18722	1.75784027779805e-11	1.33506856541624e-09	FCER1G/HLA-DPA1/CTSS/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/CD74/IFI30/HLA-DQB1/HLA-DMB/HLA-DQA1/PYCARD/HLA-DQA2/B2M/CTSL/HLA-DRB5/CTSD/TREM2/CTSV	20
GO:1902107	positive regulation of leukocyte differentiation	48/2053	157/18722	1.83930736882784e-11	1.36244990283544e-09	TYROBP/HLA-DRA/PTPRC/HLA-DRB1/CD74/EVI2B/LGALS9/TGFB1/NCKAP1L/CD86/LILRB2/CD83/LILRB4/HMGB1/FOS/CD4/CCR1/TNF/RUNX1/SASH3/PRKDC/BTK/CD46/SYK/NLRP3/RARA/IL4I1/BCL6/ZFP36L1/TREM2/ADAM8/RUNX3/TRIB1/RHOA/NOTCH2/SOX4/PNP/GATA3/NFKBIZ/XRCC6/HCLS1/JUN/INPP5D/BAD/GLI3/ID2/MDK/IL18	48
GO:1903708	positive regulation of hemopoiesis	48/2053	157/18722	1.83930736882784e-11	1.36244990283544e-09	TYROBP/HLA-DRA/PTPRC/HLA-DRB1/CD74/EVI2B/LGALS9/TGFB1/NCKAP1L/CD86/LILRB2/CD83/LILRB4/HMGB1/FOS/CD4/CCR1/TNF/RUNX1/SASH3/PRKDC/BTK/CD46/SYK/NLRP3/RARA/IL4I1/BCL6/ZFP36L1/TREM2/ADAM8/RUNX3/TRIB1/RHOA/NOTCH2/SOX4/PNP/GATA3/NFKBIZ/XRCC6/HCLS1/JUN/INPP5D/BAD/GLI3/ID2/MDK/IL18	48
GO:0007568	aging	80/2053	339/18722	1.92432257512638e-11	1.40804090862906e-09	TSPO/TIMP1/CD68/BCL2A1/TNFRSF1B/SPI1/B2M/FOS/ABI3/UCP2/SOD2/LRRK2/RETN/TYMS/SERPINF1/APP/NAMPT/KYNU/RPN2/PRKDC/VASH1/DAG1/SOD1/MME/CDK1/SERP1/TIMP2/LITAF/BCL6/CALR/ATP2B1/C1QA/NPM1/COL4A2/HAMP/ICAM1/CTSV/MSH2/KCNMB1/CHEK1/LIMS1/PAWR/HRAS/MSH6/EEF1E1/FBXO5/STAT3/HMGA1/CACYBP/GCLM/ASS1/GRB2/BRCA2/BAZ2B/CDK6/CDKN2A/SEC63/FOXO4/JUN/APEX1/RBL1/INPP5D/ERCC1/CDKN1A/CDK2/ING2/AURKB/TFCP2L1/ID2/PICALM/YPEL3/PLK2/FOXM1/LMNA/TBX3/MBD2/YBX1/MBD3/MAPK14/SERPING1	80
GO:0072593	reactive oxygen species metabolic process	63/2053	239/18722	1.97365728366006e-11	1.42674020505546e-09	TYROBP/TSPO/ITGB2/CYBB/NCF2/CYBA/NCF1/CLEC7A/TGFB1/PAGE4/RAC2/GPX1/EGFR/SOD2/LRRK2/ITGAM/ALOX5/PRDX2/TNF/TLR4/HSPD1/CD36/GSTP1/PRDX4/HVCN1/TLR6/PRDX5/PREX1/SYK/SOD1/BMP7/IFI6/VAV1/PTK2B/PDK4/DHFR/NCF4/HK2/BRCA1/DDIT4/GNAI2/PMAIP1/DCXR/TFAP2A/RHOA/STAT3/PRDX3/PRDX6/STK17A/GRB2/PRDX1/ACP5/VDAC1/CYB5R4/SOD3/PARK7/GCH1/CDKN1A/BNIP3/TRAP1/FOXM1/NDUFA13/MAPK14	63
GO:0006979	response to oxidative stress	97/2053	446/18722	2.21233914967234e-11	1.58024224976596e-09	AIF1/TXNIP/NCF1/SLC8A1/PAGE4/DUSP1/FOS/GPX1/KLF4/EGFR/UCP2/SOD2/JAK2/LRRK2/PCNA/KLF2/ALOX5/PRDX2/TNFAIP3/TLR4/NR4A2/HSPD1/PARP1/CD36/GSTP1/P4HB/APP/STAT1/HMOX1/PRDX4/PDLIM1/RPS3/PLK3/BTK/MET/TLR6/STAT6/PRDX5/SOD1/CDK1/BMP7/PSIP1/PPIA/MCTP1/TREM2/PTK2B/DHCR24/DHFR/GPX8/EZH2/BTG1/PON2/MCL1/EPAS1/PAWR/TRPM2/STAU1/SPHK1/LDHA/RBPMS/NDUFB4/SCARA3/PSMB5/NDUFA6/HDAC2/NUDT15/TXN/PRDX3/PRDX6/SIRPA/GCLM/FUT8/PRDX1/PNKP/MGST1/NET1/CHCHD2/SOD3/IDH1/NDUFS8/JUN/APEX1/PARK7/ECT2/GCH1/ERCC1/HSPA1A/PYCR2/BAD/BNIP3/RHOB/TRA2B/TRAP1/KDM6B/SIGMAR1/PLEKHA1/ALAD	97
GO:0032612	interleukin-1 production	42/2053	128/18722	2.6730721538288e-11	1.86493406081079e-09	TYROBP/MNDA/CCL3/LGALS9/CLEC7A/PYCARD/HAVCR2/LILRB4/GBP5/HMGB1/JAK2/CASP1/IFI16/TNF/TNFAIP3/TLR4/CD36/GSTP1/APP/ARRB2/LILRA2/TLR6/NLRP3/CARD16/LILRA5/TREM2/AIM2/IL16/P2RX7/CD33/CX3CR1/TLR8/NLRP12/SPHK1/ISL1/NLRP1/STAT3/HDAC2/SIRPA/MYD88/ACP5/S100A13	42
GO:0032652	regulation of interleukin-1 production	42/2053	128/18722	2.6730721538288e-11	1.86493406081079e-09	TYROBP/MNDA/CCL3/LGALS9/CLEC7A/PYCARD/HAVCR2/LILRB4/GBP5/HMGB1/JAK2/CASP1/IFI16/TNF/TNFAIP3/TLR4/CD36/GSTP1/APP/ARRB2/LILRA2/TLR6/NLRP3/CARD16/LILRA5/TREM2/AIM2/IL16/P2RX7/CD33/CX3CR1/TLR8/NLRP12/SPHK1/ISL1/NLRP1/STAT3/HDAC2/SIRPA/MYD88/ACP5/S100A13	42
GO:0002275	myeloid cell activation involved in immune response	34/2053	91/18722	3.6974720838295e-11	2.54998074746862e-09	TYROBP/FCER1G/ITGB2/CCL3/SPI1/LGALS9/CD84/PYCARD/LYN/LAT2/HAVCR2/CD300A/RAC2/HMGB1/FGR/ITGAM/PTAFR/HMOX1/GRN/STXBP2/CCR2/ADGRE2/PRAM1/DOCK2/LILRA2/BTK/SYK/TREM2/CX3CR1/IFI35/SNX4/MYD88/ANXA3/S100A13	34
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	82/2053	356/18722	3.99901071732912e-11	2.72659821636076e-09	HLA-B/FCER1G/HLA-A/HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/HLA-DMA/CD74/SLC11A1/TNFSF13B/HLA-F/TNFRSF1B/HLA-DQB1/HLA-DMB/CLEC7A/HLA-DQA1/TGFB1/NCKAP1L/WAS/HLA-DQA2/B2M/HLA-E/HAVCR2/MEF2C/LILRB1/LILRB4/MYO1G/HMGB1/CD4/HLA-DRB5/TNF/TNFAIP3/TLR4/HSPD1/IL1B/GAPT/IRF7/CCR2/SASH3/C3/BTK/CTSH/STAT6/CD46/NLRP3/IL27RA/PTPN6/UNG/SEMA4A/CD1D/IL4I1/NOTCH1/RSAD2/BCL6/TREM2/C1QA/IL6R/EMP2/SPN/ICAM1/MSH2/TLR8/C1QBP/HRAS/MSH6/STAT3/GATA3/MYD88/PHB/NFKBIZ/INPP5D/ERCC1/TCIRG1/RNF8/RIF1/TFRC/IL18/EXO1/PKN1/SERPING1	82
GO:0032611	interleukin-1 beta production	38/2053	110/18722	4.138022415111e-11	2.75097940303482e-09	TYROBP/MNDA/CCL3/LGALS9/CLEC7A/PYCARD/LILRB4/GBP5/HMGB1/JAK2/CASP1/IFI16/TNF/TNFAIP3/TLR4/CD36/GSTP1/APP/ARRB2/LILRA2/TLR6/NLRP3/CARD16/LILRA5/TREM2/AIM2/P2RX7/CD33/CX3CR1/TLR8/NLRP12/SPHK1/ISL1/NLRP1/STAT3/SIRPA/MYD88/ACP5	38
GO:0032651	regulation of interleukin-1 beta production	38/2053	110/18722	4.138022415111e-11	2.75097940303482e-09	TYROBP/MNDA/CCL3/LGALS9/CLEC7A/PYCARD/LILRB4/GBP5/HMGB1/JAK2/CASP1/IFI16/TNF/TNFAIP3/TLR4/CD36/GSTP1/APP/ARRB2/LILRA2/TLR6/NLRP3/CARD16/LILRA5/TREM2/AIM2/P2RX7/CD33/CX3CR1/TLR8/NLRP12/SPHK1/ISL1/NLRP1/STAT3/SIRPA/MYD88/ACP5	38
GO:0071222	cellular response to lipopolysaccharide	57/2053	209/18722	4.17231876126947e-11	2.75097940303482e-09	VIM/TSPO/CD68/CD14/CCL3/TNFRSF1B/ZFP36/SPI1/TGFB1/MTDH/PYCARD/LYN/CD86/LY96/LILRB2/HAVCR2/MEF2C/LILRB1/TLR2/HCK/SCIMP/HMGB1/LY86/PRDX2/CASP1/TNF/TNFAIP3/TLR4/HMGB2/IL1B/CD36/GSTP1/PTAFR/CEBPB/IRF8/CXCL10/LILRA2/NFKBIA/NLRP3/CARD16/RARA/LITAF/HAMP/ICAM1/CX3CR1/CXCL8/CD180/TRIB1/RHOA/CDK4/SIRPA/ASS1/MYD88/PABPN1/PRPF8/IL18/MAPK14	57
GO:0050866	negative regulation of cell activation	57/2053	210/18722	5.12461579120518e-11	3.34214073339468e-09	TYROBP/LAPTM5/LST1/MNDA/PTPRC/HLA-DRB1/FGL2/CD74/HLA-F/SPI1/LGALS9/NCKAP1L/CD84/LYN/CD9/CD86/LILRB2/HAVCR2/LILRB1/CD300A/LILRB4/HMGB1/FGR/TNFRSF14/PRDX2/TNFAIP3/PAG1/HMOX1/CEBPB/CD300LF/GRN/CCR2/RUNX1/BTK/GPNMB/TNFAIP8L2/PTPN6/LGALS3/IL4I1/SAMSN1/BCL6/TREM2/IRF1/SH2B3/SPN/RUNX3/PAWR/DLG5/INPP5D/DLG1/C1QTNF1/GLI3/ID2/MDK/UBASH3B/PDGFA/PKN1	57
GO:0042098	T cell proliferation	55/2053	199/18722	5.22864043842184e-11	3.37331641188506e-09	HLA-A/AIF1/HLA-DPA1/HLA-DPB1/PTPRC/HLA-DRB1/CORO1A/MSN/SLC11A1/TNFSF13B/TNFRSF1B/HLA-DMB/LGALS9/NCKAP1L/PYCARD/CD86/LILRB2/HLA-E/HAVCR2/LILRB1/LILRB4/RAC2/HMGB1/TNFRSF14/PRDX2/IL1B/CEBPB/CCR2/DOCK2/SASH3/RPS3/CD24/GPNMB/CD46/SYK/IL27RA/PTPN6/LGALS3/CD1D/IL4I1/IRF1/SPN/PAWR/CCND3/CD151/CCDC88B/PNP/IL6ST/DLG5/RPS6/PSMB10/DLG1/BTN3A1/TFRC/IL18	55
GO:0050777	negative regulation of immune response	54/2053	194/18722	5.82160133867957e-11	3.71591574809334e-09	HLA-B/HLA-A/PTPRC/HLA-DRB1/FGL2/ISG15/HLA-F/SPI1/LGALS9/SAMHD1/NCKAP1L/CD84/LYN/HLA-E/HAVCR2/LILRB1/CD300A/HCK/LILRB4/GPX1/FGR/TNFRSF14/IFI16/TNFAIP3/IRAK3/HMOX1/GRN/CCR2/ARRB2/STAT6/CD46/SYK/IL27RA/PTPN6/LGALS3/IL4I1/SAMSN1/BCL6/TREM2/CD59/OAS1/RHBDF2/RPS19/NLRC5/C1QBP/STAT2/USP15/INPP5D/PARP14/YES1/PLK2/MAPK14/SERPING1/PPARG	54
GO:0032731	positive regulation of interleukin-1 beta production	27/2053	62/18722	6.12192486893285e-11	3.86647886458917e-09	TYROBP/MNDA/CCL3/LGALS9/CLEC7A/PYCARD/GBP5/HMGB1/JAK2/CASP1/IFI16/TNF/TLR4/CD36/APP/LILRA2/TLR6/NLRP3/LILRA5/AIM2/P2RX7/TLR8/NLRP12/ISL1/NLRP1/STAT3/MYD88	27
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	20/2053	36/18722	7.42243120372576e-11	4.6390195023286e-09	FCER1G/HLA-DPA1/CTSS/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/CD74/IFI30/HLA-DQB1/HLA-DMB/HLA-DQA1/PYCARD/HLA-DQA2/B2M/CTSL/HLA-DRB5/CTSD/TREM2/CTSV	20
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	18/2053	30/18722	1.15541503351643e-10	7.14689711453465e-09	FCER1G/HLA-DPA1/CTSS/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/CD74/IFI30/HLA-DQB1/HLA-DMB/HLA-DQA1/HLA-DQA2/B2M/CTSL/HLA-DRB5/CTSD/CTSV	18
GO:0006909	phagocytosis	73/2053	308/18722	1.18359231937255e-10	7.2464835879952e-09	TYROBP/FCER1G/AIF1/PTPRC/ITGB2/CD14/CORO1A/NCF2/FCN1/SLC11A1/CYBA/FCGR1A/PECAM1/CLEC7A/MSR1/NCKAP1L/PYCARD/LYN/TLR2/CD300A/HCK/RAC2/MYO1G/ITGAL/HMGB1/FGR/ITGAM/TNF/TLR4/COLEC12/IL1B/CD36/IRF8/CD300LF/CCR2/DOCK2/C3/CNN2/TGM2/MET/IL2RG/SYK/SIRPB1/CAMK1D/SOD1/RARA/CSK/LYST/ITGB1/CD93/CALR/TREM2/VAV1/ARHGAP25/MARCO/NCF4/CD302/SPHK1/SYT7/ITGAV/SIRPA/MYD88/PLSCR1/RAP1A/ANXA3/ICAM3/RHOG/VAV3/CORO1C/EIF2AK1/YES1/PTK2/MYO7A	73
GO:0044403	biological process involved in symbiotic interaction	70/2053	290/18722	1.19902290792826e-10	7.26680550259551e-09	HLA-DRB1/LGALS1/CD74/CXCR4/CCL3/FCN1/IFITM2/CCL4/LGALS9/CD86/TRIM22/FN1/CTSB/IFITM3/GPX1/EGFR/ITGA5/CTSL/CD4/TNFRSF14/IFIT1/CLEC5A/TREM1/HSPD1/P4HB/SIVA1/RPSA/SELPLG/CD46/HSP90AB1/DAG1/BSG/NUCKS1/CIITA/CDK1/ITGB1/PPIA/DPP4/PPIB/ICAM1/SIGLEC1/IFI27/PHB2/PSMC3/CX3CR1/CXCL8/HSPA8/DDB1/NRP1/ITGB5/SLC1A5/ANPEP/TCP1/ITGAV/MYD88/PLSCR1/TRIM38/PHB/EIF2AK4/JUN/SLC52A1/HSPA1A/TFRC/CHMP4C/INSR/TRIM28/CFL1/GAPDH/SLC3A2/DYNLT1	70
GO:0097529	myeloid leukocyte migration	58/2053	220/18722	1.22462448014625e-10	7.34774688087748e-09	FCER1G/AIF1/S100A8/CCL3L3/ITGB2/CD74/CCL3/CSF1R/SPI1/CCL4/PECAM1/NCKAP1L/C5AR1/LYN/CD9/C3AR1/CD300A/S100A12/DUSP1/RAC2/HMGB1/VEGFA/CCR1/TREM1/CCR2/PTGER4/ADGRE2/CXCL10/PREX1/SYK/CAMK1D/BSG/JAML/PPIA/LGALS3/DPP4/S100A9/PPIB/TREM2/PLA2G7/ADAM8/IL6R/VAV1/PTK2B/FLT1/CX3CR1/CXCL8/RPS19/C1QBP/RIN3/SIRPA/JAM3/MYD88/RHOG/VAV3/MPP1/MDK/PTK2	58
GO:1901988	negative regulation of cell cycle phase transition	63/2053	249/18722	1.2790707523309e-10	7.59844011285684e-09	ZFP36L2/DUSP1/KLF4/PRKDC/PLK3/GPNMB/CLSPN/CDK1/CENPF/ZWINT/ZFP36L1/MAD2L1/CDC6/CCND1/CTDSPL/BRCA1/WEE1/EZH2/NAE1/MSH2/DTL/CHEK1/CDT1/RPA2/TRIAP1/FBXO5/RAD21/TOPBP1/BLM/SOX4/FBXO6/BRD7/RGCC/WDR76/ATF5/GTSE1/BUB3/TPR/FANCD2/CDC45/NDC80/EIF2AK4/FOXO4/TIPIN/RBL1/TTK/DLG1/CDKN1A/TIMELESS/CDK2AP2/CDK2/AURKB/LCMT1/CHMP4C/PLK2/PRPF19/E2F1/BRCC3/BUB1B/MAPK14/MDC1/E2F7/KNTC1	63
GO:0050764	regulation of phagocytosis	34/2053	95/18722	1.45020513777796e-10	8.53061845751742e-09	FCER1G/PTPRC/SLC11A1/CYBA/CLEC7A/NCKAP1L/PYCARD/TLR2/CD300A/HCK/HMGB1/FGR/TNF/IL1B/CD36/CD300LF/DOCK2/C3/CNN2/TGM2/IL2RG/SYK/SIRPB1/CAMK1D/SOD1/CSK/CALR/TREM2/SPHK1/SYT7/ITGAV/SIRPA/PLSCR1/RAP1A	34
GO:0031663	lipopolysaccharide-mediated signaling pathway	26/2053	60/18722	1.58192198396061e-10	9.21507951821713e-09	CD14/CCL3/SPI1/TGFB1/MTDH/LYN/LY96/TLR2/HCK/SCIMP/LY86/PRDX2/TNF/TNFAIP3/TLR4/IL1B/CD36/PTAFR/LILRA2/NFKBIA/CARD16/CD180/TRIB1/MYD88/IL18/MAPK14	26
GO:1901224	positive regulation of NIK/NF-kappaB signaling	28/2053	69/18722	2.04841503291625e-10	1.18177790360553e-08	LAPTM5/CD14/LGALS9/CD86/HAVCR2/TLR2/HMGB1/EGFR/TNF/TLR4/IL1B/APP/RPS3/TLR7/CALR/TREM2/PHB2/NLRP12/LIMS1/SPHK1/IFI35/RHOA/PHB/RTKN2/TRIP6/IL18/NFAT5/ACTN4	28
GO:0045088	regulation of innate immune response	57/2053	218/18722	2.49509959427661e-10	1.42577119672949e-08	HLA-B/TYROBP/HLA-A/MNDA/FCN1/ISG15/HLA-F/NCF1/SPI1/LGALS9/CLEC7A/SAMHD1/PYCARD/LYN/HLA-E/HAVCR2/LILRB1/HCK/GBP5/HMGB1/FGR/IFI16/TNFAIP3/IRAK3/TLR4/HMGB2/GRN/IRF7/ARRB2/CADM1/PRKDC/LILRA2/HSP90AA1/SYK/HSP90AB1/PTPN6/CD1D/PARP9/TREM2/ADAM8/VAV1/IRF1/AIM2/OAS1/TLR8/RPS19/BIRC3/NLRC5/STAT2/IFI35/USP15/PLSCR1/XRCC5/XRCC6/PARP14/SERPING1/PPARG	57
GO:1901991	negative regulation of mitotic cell cycle phase transition	50/2053	179/18722	2.58851815970007e-10	1.46519895832079e-08	ZFP36L2/DUSP1/KLF4/PRKDC/PLK3/GPNMB/CLSPN/CDK1/CENPF/ZWINT/ZFP36L1/MAD2L1/CDC6/CCND1/CTDSPL/BRCA1/WEE1/EZH2/NAE1/DTL/CHEK1/CDT1/RPA2/TRIAP1/FBXO5/RAD21/TOPBP1/BLM/SOX4/BRD7/RGCC/GTSE1/BUB3/TPR/NDC80/FOXO4/RBL1/TTK/DLG1/CDKN1A/CDK2AP2/CDK2/AURKB/LCMT1/CHMP4C/PLK2/BRCC3/BUB1B/E2F7/KNTC1	50
GO:0071346	cellular response to interferon-gamma	38/2053	118/18722	4.31020417711587e-10	2.41693692174722e-08	AIF1/HLA-DPA1/VIM/CCL3L3/CCL3/CCL4/LGALS9/GBP4/GBP2/WAS/TLR2/HCK/GBP5/JAK2/CASP1/TLR4/GBP1/STAT1/IRF8/JAK1/IFNGR2/HSP90AB1/PARP9/IRF1/ICAM1/RPL13A/NLRC5/ACTR2/ZYX/SIRPA/MYO1C/ASS1/ACTR3/SP100/PARP14/IFNGR1/GAPDH/PPARG	38
GO:0002695	negative regulation of leukocyte activation	51/2053	187/18722	4.36689841669181e-10	2.42605467593989e-08	TYROBP/LAPTM5/LST1/MNDA/PTPRC/HLA-DRB1/FGL2/CD74/HLA-F/SPI1/LGALS9/NCKAP1L/CD84/LYN/CD86/LILRB2/HAVCR2/LILRB1/CD300A/LILRB4/HMGB1/FGR/TNFRSF14/PRDX2/TNFAIP3/PAG1/HMOX1/CEBPB/CD300LF/GRN/CCR2/RUNX1/BTK/GPNMB/TNFAIP8L2/PTPN6/LGALS3/IL4I1/SAMSN1/BCL6/IRF1/SPN/RUNX3/PAWR/DLG5/INPP5D/DLG1/GLI3/ID2/MDK/PKN1	51
GO:0046718	viral entry into host cell	43/2053	144/18722	4.68504225521763e-10	2.57892234232163e-08	HLA-DRB1/LGALS1/CD74/CXCR4/FCN1/IFITM2/LGALS9/CD86/TRIM22/CTSB/IFITM3/EGFR/ITGA5/CTSL/CD4/TNFRSF14/CLEC5A/P4HB/SIVA1/RPSA/SELPLG/CD46/DAG1/BSG/CIITA/CDK1/ITGB1/DPP4/ICAM1/SIGLEC1/NRP1/ITGB5/SLC1A5/ANPEP/ITGAV/PLSCR1/TRIM38/PHB/SLC52A1/HSPA1A/TFRC/SLC3A2/DYNLT1	43
GO:0045637	regulation of myeloid cell differentiation	55/2053	210/18722	4.79372824149084e-10	2.61476085899501e-08	TYROBP/HLA-DRB1/CD74/EVI2B/CCL3/ISG15/ZFP36/SPI1/TGFB1/NCKAP1L/MAFB/LYN/B2M/MEF2C/LILRB1/LILRB3/LILRB4/HMGB1/FOS/CD4/FBN1/CCR1/TNF/TLR4/HMGB2/STAT1/CEBPB/IRF7/RUNX1/PRKDC/NFKBIA/RARA/ZFP36L1/TREM2/PTK2B/TRIB1/FAM210B/CIB1/NOTCH2/STAT3/SCIN/CDK6/PITHD1/RASSF2/HCLS1/JUN/INPP5D/HSPA1A/ID2/NME1/UBASH3B/HSPA9/MAPK14/RCOR1/MEIS2	55
GO:0140014	mitotic nuclear division	68/2053	287/18722	5.17856126876254e-10	2.79922230743921e-08	FLNA/DUSP1/IL1B/RANBP1/RAN/MKI67/PRC1/BMP7/SMC2/CENPF/ZWINT/SMC3/NUSAP1/MAD2L1/CDC6/ANAPC11/PHB2/SMC4/UBE2C/CHEK1/CDT1/KPNB1/CENPK/SPHK1/RHOA/CDCA5/KIF23/PKMYT1/FBXO5/RAD21/UBE2S/NUF2/TPX2/NCAPD3/NCAPH/RGCC/AURKAIP1/DSCC1/LRP5/MYBL2/BUB3/ANLN/KIF20B/TPR/KIF22/NDC80/EML4/OBSL1/KMT5A/EPS8/STAG1/TTK/DSN1/NCAPG/HSPA1A/NUDC/AURKB/LCMT1/CHMP4C/INSR/KIF4A/DRG1/CDCA8/BUB1B/KIF11/KNTC1/NCAPG2/KIFC1	68
GO:0000302	response to reactive oxygen species	57/2053	222/18722	5.29342616331952e-10	2.83576401606403e-08	TXNIP/NCF1/SLC8A1/DUSP1/FOS/GPX1/KLF4/EGFR/UCP2/SOD2/LRRK2/PCNA/KLF2/PRDX2/TNFAIP3/HSPD1/CD36/GSTP1/STAT1/HMOX1/RPS3/PLK3/BTK/MET/STAT6/PRDX5/SOD1/CDK1/BMP7/PTK2B/DHFR/EZH2/PAWR/TRPM2/SPHK1/LDHA/HDAC2/NUDT15/TXN/PRDX3/SIRPA/PRDX1/NET1/SOD3/JUN/APEX1/PARK7/ECT2/GCH1/BAD/BNIP3/RHOB/TRA2B/TRAP1/KDM6B/SIGMAR1/PLEKHA1	57
GO:0034101	erythrocyte homeostasis	40/2053	129/18722	5.42168034716207e-10	2.87876832592676e-08	ISG15/ZFP36/SPI1/NCKAP1L/MAFB/LYN/B2M/JAK2/VEGFA/KLF2/HMGB2/STAT1/HMOX1/RPS17/PRKDC/RPS14/SLC25A5/BCL6/ZFP36L1/IKZF1/SH2B3/RPS19/EPAS1/FAM210B/STAT3/GATA3/RPS6/PRDX1/CDK6/HCLS1/INPP5D/KMT2E/HSPA1A/ID2/TGFBR3/SMAD5/HSPA9/MAPK14/RCOR1/NCAPG2	40
GO:0070665	positive regulation of leukocyte proliferation	44/2053	150/18722	5.55655949019109e-10	2.92450499483742e-08	HLA-A/AIF1/HLA-DPA1/HLA-DPB1/PTPRC/CD74/CORO1A/BST2/TNFSF13B/CSF1R/HLA-DMB/LGALS9/NCKAP1L/PYCARD/LYN/CD86/LILRB2/HLA-E/HAVCR2/MEF2C/HMGB1/TLR4/IL1B/CCR2/SASH3/RPS3/CD24/CD46/SYK/IL27RA/CD1D/BCL6/GPR183/SLC39A10/CCDC88B/PNP/IL6ST/MYD88/VAV3/CDKN1A/TFRC/PTK2/IL18/CD320	44
GO:0001774	microglial cell activation	22/2053	47/18722	6.61063665736802e-10	3.44902782123549e-08	TYROBP/AIF1/PTPRC/ITGB2/CCL3/C5AR1/TLR2/JAK2/LRRK2/TLR1/ITGAM/TNF/APP/NAMPT/GRN/TLR6/IFNGR2/TREM2/C1QA/CX3CR1/SPHK1/IFNGR1	22
GO:0002687	positive regulation of leukocyte migration	41/2053	135/18722	6.70235983352706e-10	3.46673784492779e-08	AIF1/CD74/CCL3/CSF1R/SPI1/CCL4/LGALS9/NCKAP1L/GPSM3/PYCARD/C5AR1/C3AR1/RAC2/HMGB1/VEGFA/TNFRSF14/CCR1/TNF/APP/ITGA4/PTAFR/CCR2/CXCL10/CAMK1D/LGALS3/CALR/TREM2/PLA2G7/ADAM8/IL6R/PTK2B/SPN/ICAM1/CX3CR1/CXCL8/C1QBP/RHOA/JAM3/MDK/PTN/PTK2	41
GO:0044409	entry into host	44/2053	151/18722	7.0191310037169e-10	3.59955436088046e-08	HLA-DRB1/LGALS1/CD74/CXCR4/FCN1/IFITM2/LGALS9/CD86/TRIM22/CTSB/IFITM3/EGFR/ITGA5/CTSL/CD4/TNFRSF14/CLEC5A/P4HB/SIVA1/RPSA/SELPLG/CD46/DAG1/BSG/CIITA/CDK1/ITGB1/DPP4/ICAM1/SIGLEC1/CXCL8/NRP1/ITGB5/SLC1A5/ANPEP/ITGAV/PLSCR1/TRIM38/PHB/SLC52A1/HSPA1A/TFRC/SLC3A2/DYNLT1	44
GO:0051054	positive regulation of DNA metabolic process	53/2053	201/18722	7.58804213399709e-10	3.85832650881208e-08	PTPRC/TGFB1/WAS/HMGB1/KLF4/EGFR/PCNA/PARP1/ARRB2/RPS3/PRKDC/FUS/STAT6/HSP90AA1/HSP90AB1/RAD51AP1/PKIB/PARP9/PTK2B/RAD51/RFC3/HNRNPA1/RFC4/BRCA1/RFC2/MSH2/ACTR2/RGCC/HNRNPD/TCP1/DSCC1/CCT6A/CCT2/XRCC5/RAD50/PNKP/ANXA3/DTX3L/GNL3/HNRNPA2B1/ERCC1/TIMELESS/CCT4/RNF8/AURKB/RIF1/TFRC/TRIM28/CCT8/FOXM1/MAP3K4/UBE2N/BRCC3	53
GO:0002262	myeloid cell homeostasis	45/2053	157/18722	8.11787711943093e-10	4.09304728710803e-08	ISG15/ZFP36/SPI1/NCKAP1L/MAFB/LYN/B2M/HMGB1/JAK2/VEGFA/KLF2/HMGB2/STAT1/HMOX1/RPS17/CCR2/PRKDC/SOD1/RPS14/SLC25A5/BCL6/ZFP36L1/IKZF1/SH2B3/HAMP/RPS19/EPAS1/FAM210B/STAT3/GATA3/RPS6/JAM3/PRDX1/CDK6/HCLS1/INPP5D/KMT2E/HSPA1A/ID2/TGFBR3/SMAD5/HSPA9/MAPK14/RCOR1/NCAPG2	45
GO:0007059	chromosome segregation	77/2053	346/18722	8.60101630247466e-10	4.28629834258521e-08	DUSP1/RPS3/FEN1/TOP2A/RAN/CENPW/MKI67/PRC1/SMC2/SLC25A5/CENPF/ZWINT/SMC3/NUSAP1/MAD2L1/CDC6/CCNE1/CENPN/ANAPC11/RMI2/BRCA1/SPC25/PHB2/BIRC5/SMC4/UBE2C/CDT1/RAD51C/KPNB1/CENPK/ACTR2/CDCA5/KIF23/FBXO5/RAD21/CCNE2/NUF2/CENPH/NCAPD3/NCAPH/DSCC1/BEX4/BUB3/PLSCR1/ESCO2/TPR/FANCD2/KIF22/SKA2/PSMC3IP/PMF1/ACTR3/NDC80/EML4/SRPK1/KMT5A/STAG1/TTK/MIS18A/DSN1/ECT2/NCAPG/CIAO1/TOP2B/NUDC/AURKB/TLK1/SKA3/LCMT1/CHMP4C/NTMT1/KIF4A/CDCA8/BUB1B/KNTC1/NCAPG2/KIFC1	77
GO:0022408	negative regulation of cell-cell adhesion	52/2053	196/18722	8.64403499088017e-10	4.28629834258521e-08	LAPTM5/HLA-DRB1/FGL2/FXYD5/CD74/SPI1/LGALS9/TGFB1/NCKAP1L/CD9/CD86/LILRB2/HAVCR2/LILRB1/CD300A/LILRB4/HMGB1/KLF4/SPINT2/JAK2/MBP/VEGFA/TNFRSF14/CDH1/PRDX2/PAG1/MYADM/CEBPB/IL1RN/RUNX1/GPNMB/TNFAIP8L2/PTPN6/LGALS3/IL4I1/NOTCH1/BCL6/IRF1/SH2B3/SPN/RUNX3/PAWR/RDX/RGCC/DLG5/ASS1/DLG1/C1QTNF1/GLI3/MDK/UBASH3B/PTK2	52
GO:0097191	extrinsic apoptotic signaling pathway	56/2053	219/18722	8.83047429619138e-10	4.34285621124166e-08	PTPRC/BCL2A1/TNFSF10/TNFRSF1B/SPI1/TGFB1/PYCARD/SKIL/GPX1/JAK2/ITGA6/PRDX2/TNF/TNFAIP3/HMGB2/IL1B/GSTP1/G0S2/HMOX1/SIVA1/KRT18/LGALS3/PDIA3/IFI6/TIMP3/TNFSF12/IL6R/P2RX7/ICAM1/IFI27/BRCA1/KRT8/PMAIP1/MCL1/ITM2C/NRP1/SIAH2/CIB1/BCL2L12/ITGAV/GCLM/TNFRSF12A/YAP1/CASP8AP2/PARP2/SP100/PARK7/ARHGEF2/HSPA1A/BAD/ATF3/STK4/LMNA/GABARAP/PEA15/NDUFA13	56
GO:0051052	regulation of DNA metabolic process	79/2053	359/18722	9.06626727408109e-10	4.42256940199078e-08	PTPRC/SPI1/TGFB1/WAS/DUSP1/HMGB1/KLF4/EGFR/PCNA/PARP1/DEK/ARRB2/RPS3/PRKDC/FUS/STAT6/HSP90AA1/HSP90AB1/IL27RA/NUCKS1/RAD51AP1/PKIB/PARP9/BCL6/NPM1/PTK2B/RAD51/RFC3/RMI2/HNRNPA1/RFC4/BRCA1/RFC2/GJA1/MSH2/CHEK1/CDT1/RPA2/USP1/MSH6/ACTR2/BLM/RGCC/HNRNPD/TCP1/GATA3/DSCC1/CCT6A/CCT2/XRCC5/RAD50/KDM1B/PNKP/TFDP1/ANXA3/DTX3L/MAGEF1/GNL3/HNRNPA2B1/WDR18/MIS18A/ERCC1/CDKN1A/TIMELESS/CCT4/RNF8/AURKB/RIF1/TFRC/POLQ/TRIM28/CCT8/FOXM1/MAP3K4/MBD2/UBE2N/BRCC3/MBD3/FIGNL1	79
GO:0002573	myeloid leukocyte differentiation	54/2053	208/18722	9.72311766545753e-10	4.70473435425365e-08	TYROBP/HLA-DRB1/CD74/EVI2B/CCL3/CSF1R/SPI1/TGFB1/MAFB/LYN/LILRB1/LILRB3/TLR2/LILRB4/FOS/JUNB/VEGFA/SNX10/CD4/FBN1/OSCAR/CCR1/IFI16/TNF/TLR4/PARP1/APP/CEBPB/IRF7/RUNX1/RARA/ZFP36L1/TREM2/GPR183/GAB3/TRIB1/NOTCH2/GATA3/CDK6/RASSF2/HCLS1/JUN/INPP5D/EIF2AK1/TCIRG1/ID2/TFRC/NME1/UBASH3B/ITGB8/MAPK14/PPARG/GPC3/GLO1	54
GO:0000075	cell cycle checkpoint signaling	47/2053	169/18722	1.03643212803418e-09	4.97487421456404e-08	DUSP1/PRKDC/PLK3/CLSPN/CDK1/CENPF/ZWINT/MAD2L1/CDC6/CCND1/BRCA1/NAE1/MSH2/DTL/CHEK1/CDT1/RPA2/TRIAP1/TOPBP1/BLM/SOX4/FBXO6/WDR76/GTSE1/BUB3/TPR/FANCD2/CDC45/NDC80/EIF2AK4/FOXO4/TIPIN/TTK/CDKN1A/TIMELESS/CDK2/AURKB/LCMT1/CHMP4C/PLK2/PRPF19/E2F1/BRCC3/BUB1B/MAPK14/MDC1/KNTC1	47
GO:0002886	regulation of myeloid leukocyte mediated immunity	24/2053	56/18722	1.05353210033831e-09	5.01681952542052e-08	TYROBP/ITGB2/SPI1/LGALS9/CD84/LYN/HLA-E/CD300A/RAC2/FGR/ITGAM/PTAFR/HMOX1/STXBP2/CCR2/ADGRE2/PRAM1/C3/BTK/SYK/CX3CR1/SNX4/DDX1/DDX58	24
GO:0052126	movement in host environment	48/2053	175/18722	1.1474895793754e-09	5.42121061122237e-08	HLA-DRB1/LGALS1/CD74/CXCR4/FCN1/IFITM2/LGALS9/CD86/TRIM22/CTSB/IFITM3/EGFR/ITGA5/CTSL/CD4/TNFRSF14/CLEC5A/P4HB/SIVA1/RPSA/SELPLG/CD46/DAG1/BSG/CIITA/CDK1/ITGB1/PPIA/DPP4/ICAM1/SIGLEC1/CXCL8/DDB1/NRP1/ITGB5/SLC1A5/ANPEP/ITGAV/PLSCR1/TRIM38/PHB/SLC52A1/HSPA1A/TFRC/CHMP4C/TRIM28/SLC3A2/DYNLT1	48
GO:0070997	neuron death	79/2053	361/18722	1.1904772288717e-09	5.58036201033611e-08	TYROBP/ITGB2/CORO1A/CCL3/HLA-F/TNFRSF1B/C5AR1/SORL1/MEF2C/FOS/GPX1/SOD2/JAK2/LRRK2/ITGAM/TNF/TLR4/NR4A2/HSPD1/PARP1/SERPINF1/APP/HMOX1/CEBPB/NAMPT/GRN/ARRB2/GPNMB/TLR6/CTSZ/HSP90AB1/SOD1/TREM2/C1QA/ADAM8/PTK2B/DHCR24/HSPA5/NAIP/DDIT4/RASA1/PPT1/BTG2/SET/CX3CR1/NAE1/MSH2/UBB/MCL1/HRAS/TFAP2A/CHP1/TRPM2/NRP1/ISL1/RHOA/NLRP1/STAT3/PSMC1/GATA3/GCLM/MYBL2/PARP2/NENF/SIAH1/FIS1/JUN/SLC9A1/PARK7/USP53/BAD/BNIP3/REL/MDK/PICALM/SIGMAR1/EIF4G1/GAPDH/XRCC2	79
GO:1901222	regulation of NIK/NF-kappaB signaling	36/2053	112/18722	1.30670306085729e-09	6.07768865515018e-08	LAPTM5/TMSB4X/CD14/SPI1/LGALS9/CD86/HAVCR2/TLR2/HMGB1/EGFR/TNF/TLR4/IL1B/APP/RPS3/TLR7/NFKBIA/NLRP3/BMP7/LITAF/CALR/TREM2/PHB2/NLRP12/LIMS1/SPHK1/IFI35/RHOA/PRDX1/PHB/RASSF2/RTKN2/TRIP6/IL18/NFAT5/ACTN4	36
GO:0006302	double-strand break repair	61/2053	251/18722	1.3943990490295e-09	6.4356879185977e-08	SAMHD1/WAS/HMGB1/MCM7/HMGB2/PARP1/DEK/MCM3/MCM5/PRKDC/RPA3/MCM6/FEN1/FUS/NUCKS1/RAD51AP1/PARP9/RAD51/MCM4/GINS2/RMI2/BRCA1/MSH2/CHEK1/RPA2/MCM2/RAD51C/ACTR2/CDCA5/CIB1/RAD21/BLM/PSMD14/BRCA2/ESCO2/FANCD2/CDC45/XRCC5/RAD50/PARP2/PNKP/DTX3L/MAGEF1/RPA1/MMS22L/XRCC6/POLA1/DDX1/ERCC1/TIMELESS/RNF8/RIF1/POLQ/RBBP8/VCP/PRPF19/FOXM1/UBE2N/BRCC3/FIGNL1/XRCC2	61
GO:0002685	regulation of leukocyte migration	54/2053	210/18722	1.41351894206785e-09	6.45369883171853e-08	AIF1/CD74/CCL3/MSN/CSF1R/SPI1/CCL4/LGALS9/NCKAP1L/GPSM3/PYCARD/C5AR1/LYN/CD9/C3AR1/CD300A/DUSP1/RAC2/HMGB1/VEGFA/TNFRSF14/CCR1/TNF/APP/ITGA4/PTAFR/HMOX1/CCR2/PTGER4/CXCL10/CAMK1D/IL27RA/LGALS3/DPP4/CALR/TREM2/PLA2G7/ADAM8/IL6R/PTK2B/SPN/ICAM1/CX3CR1/CXCL8/C1QBP/RHOA/RIN3/JAM3/MYD88/RHOG/MPP1/MDK/PTN/PTK2	54
GO:0062197	cellular response to chemical stress	75/2053	337/18722	1.41981374297808e-09	6.45369883171853e-08	AIF1/TSPO/NCF1/PAGE4/FOS/GPX1/KLF4/EGFR/SOD2/JAK2/LRRK2/PCNA/KLF2/ALOX5/PRDX2/TNFAIP3/TLR4/NR4A2/PARP1/CD36/P4HB/HMOX1/SLC2A1/RPS3/BTK/MET/RCSD1/TLR6/STAT6/PRDX5/SOD1/CDK1/BMP7/PPIA/ZFP36L1/TREM2/LRRC8C/DHFR/GPX8/EZH2/AKR1B1/MCL1/EPAS1/PAWR/TRPM2/STAU1/SPHK1/HDAC2/TXN/PRDX3/SIRPA/FUT8/PRDX1/XRCC5/MGST1/NET1/CHCHD2/SOD3/XRCC6/JUN/APEX1/PARK7/ECT2/ARHGEF2/GCH1/HSPA1A/PYCR2/BAD/BNIP3/RHOB/EFHD1/TRAP1/KDM6B/SIGMAR1/PLEKHA1	75
GO:0010948	negative regulation of cell cycle process	68/2053	294/18722	1.53284554670036e-09	6.91509269188134e-08	ZFP36L2/DUSP1/KLF4/PRKDC/PLK3/GPNMB/CLSPN/CDK1/BMP7/CENPF/ZWINT/BCL6/ZFP36L1/NPM1/MAD2L1/CDC6/CCND1/CTDSPL/BRCA1/WEE1/EZH2/NAE1/MSH2/DTL/CHEK1/CDT1/RPA2/TRIAP1/FBXO5/RAD21/TOPBP1/BLM/SOX4/FBXO6/BRD7/RGCC/AURKAIP1/WDR76/ATF5/GTSE1/BUB3/TPR/FANCD2/CDC45/NDC80/EIF2AK4/FOXO4/TIPIN/RBL1/TTK/DLG1/CDKN1A/TIMELESS/CDK2AP2/CDK2/AURKB/LCMT1/CHMP4C/PLK2/PRPF19/CCP110/E2F1/BRCC3/BUB1B/MAPK14/MDC1/E2F7/KNTC1	68
GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	27/2053	70/18722	1.65544877040082e-09	7.41245718089918e-08	HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DMB/HLA-DQA1/TGFB1/HLA-DQA2/B2M/HLA-DRB5/HSPD1/GAPT/BTK/STAT6/IL27RA/UNG/BCL6/MSH2/MSH6/ERCC1/RNF8/RIF1/TFRC/EXO1	27
GO:0006270	DNA replication initiation	18/2053	34/18722	1.90884663569731e-09	8.48376282532139e-08	MCM7/MCM3/MCM5/ORC6/MCM6/CDC6/MCM4/CCNE1/CDT1/MCM2/MCM10/CCNE2/TOPBP1/CDC45/WDR18/POLA1/PURA/NOC3L	18
GO:0002221	pattern recognition receptor signaling pathway	47/2053	172/18722	1.94917240387349e-09	8.59929001708892e-08	CTSS/CD14/FCN1/CYBA/LYN/LY96/PIK3AP1/HAVCR2/TLR2/CD300A/SCIMP/HMGB1/TLR1/CLEC4E/OASL/TNFAIP3/IRAK3/TLR4/COLEC12/HSPD1/CD36/CD300LF/IRF7/ARRB2/LILRA2/BTK/TLR6/TLR7/NFKBIA/RSAD2/TREM2/IRF1/OAS1/PHB2/SLC15A3/TLR8/BIRC3/C1QBP/IFI35/UNC93B1/USP15/MAPKAPK3/MYD88/LGR4/PHB/HSPA1A/DDX58	47
GO:0007093	mitotic cell cycle checkpoint signaling	39/2053	129/18722	2.00939517570593e-09	8.80027084250774e-08	DUSP1/PRKDC/PLK3/CLSPN/CDK1/CENPF/ZWINT/MAD2L1/CDC6/CCND1/BRCA1/NAE1/MSH2/DTL/CHEK1/CDT1/RPA2/TRIAP1/TOPBP1/BLM/SOX4/GTSE1/BUB3/TPR/FANCD2/NDC80/FOXO4/TIPIN/TTK/CDKN1A/CDK2/AURKB/LCMT1/CHMP4C/PLK2/BRCC3/BUB1B/MDC1/KNTC1	39
GO:0006457	protein folding	54/2053	212/18722	2.0415328736236e-09	8.87622988532001e-08	CD74/B2M/HSP90B1/LMAN1/HSPD1/P4HB/PDIA6/GRN/PRDX4/PFDN5/QSOX1/HSP90AA1/HSP90AB1/PPIA/PDIA3/PPIB/CALR/CCDC47/PPIC/HSPE1/PDIA4/HSPA5/ERP29/HSPA8/FKBP5/HSPA6/DNAJC21/TCP1/ARL2/CCT6A/PDCD5/CCT2/BAG2/NUDCD2/SDF2L1/DNAJC19/HSPA14/TBCA/HSPA1A/FKBP1A/SGTB/NUDC/DNAJC1/CCT4/SIL1/SNRNP70/PFDN1/TRAP1/P3H1/CCT8/PDIA5/HSPA9/ST13/DNAJB14	54
GO:0032615	interleukin-12 production	25/2053	62/18722	2.22578828836601e-09	9.53909266442574e-08	HLA-B/LAPTM5/LGALS9/CLEC7A/LILRB1/TLR2/SCIMP/HMGB1/IRAK3/TLR4/HSPD1/CD36/IRF8/ARRB2/SYK/LILRA5/IRF1/IL16/IRF5/TLR8/C1QBP/ISL1/ACP5/MDK/MAPK14	25
GO:0032655	regulation of interleukin-12 production	25/2053	62/18722	2.22578828836601e-09	9.53909266442574e-08	HLA-B/LAPTM5/LGALS9/CLEC7A/LILRB1/TLR2/SCIMP/HMGB1/IRAK3/TLR4/HSPD1/CD36/IRF8/ARRB2/SYK/LILRA5/IRF1/IL16/IRF5/TLR8/C1QBP/ISL1/ACP5/MDK/MAPK14	25
GO:0007162	negative regulation of cell adhesion	69/2053	303/18722	2.33606170953265e-09	9.94068812567084e-08	LAPTM5/PTPRC/HLA-DRB1/FGL2/LGALS1/FXYD5/CD74/SPI1/ARHGDIB/LGALS9/TGFB1/NCKAP1L/TGFBI/CD9/CD86/LILRB2/HAVCR2/LILRB1/FBLN1/CD300A/LILRB4/DUSP1/HMGB1/KLF4/SPINT2/JAK2/MBP/VEGFA/TNFRSF14/PLXNC1/CDH1/PRDX2/PAG1/MYADM/GBP1/CEBPB/IL1RN/RUNX1/GPNMB/TNFAIP8L2/PTPN6/LGALS3/IL4I1/NOTCH1/BCL6/IRF1/SH2B3/SPN/SEMA6A/RASA1/KANK1/TACSTD2/RUNX3/PAWR/RDX/RHOA/RGCC/DLG5/ASS1/JAM3/CDKN2A/CORO1C/DLG1/C1QTNF1/GLI3/MDK/UBASH3B/PTK2/ACTN4	69
GO:0071674	mononuclear cell migration	51/2053	196/18722	2.59153275733449e-09	1.09501384112725e-07	AIF1/CCL3L3/CXCR4/CCL3/MSN/CSF1R/SPI1/CCL4/PECAM1/LGALS9/PYCARD/C5AR1/LYN/C3AR1/S100A12/DUSP1/MYO1G/ITGAL/HMGB1/TNFRSF14/ALOX5/CCR1/TNF/CXCL16/APP/ITGA4/CCR2/CXCL10/IL27RA/JAML/LGALS3/CALR/PLA2G7/ADAM8/IL6R/PTK2B/GPR183/SPN/ICAM1/FLT1/CX3CR1/NLRP12/RPS19/C1QBP/TRPM2/RHOA/GATA3/SIRPA/EPS8/MDK/PTK2	51
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	46/2053	168/18722	2.68963852274854e-09	1.12456941481575e-07	HLA-B/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/SLC11A1/TNFSF13B/HLA-F/TNFRSF1B/CLEC7A/TGFB1/NCKAP1L/WAS/B2M/HLA-E/HAVCR2/MEF2C/LILRB1/LILRB4/HMGB1/CD4/TNF/TNFAIP3/HSPD1/IL1B/CCR2/SASH3/C3/BTK/STAT6/CD46/NLRP3/IL27RA/PTPN6/CD1D/IL4I1/RSAD2/BCL6/TREM2/MSH2/GATA3/NFKBIZ/RIF1/TFRC/IL18/PKN1	46
GO:0051250	negative regulation of lymphocyte activation	44/2053	157/18722	2.69896659555781e-09	1.12456941481575e-07	TYROBP/LAPTM5/LST1/MNDA/HLA-DRB1/FGL2/CD74/HLA-F/LGALS9/NCKAP1L/LYN/CD86/LILRB2/HAVCR2/LILRB1/CD300A/LILRB4/HMGB1/FGR/TNFRSF14/PRDX2/TNFAIP3/PAG1/CEBPB/RUNX1/BTK/GPNMB/TNFAIP8L2/PTPN6/LGALS3/IL4I1/SAMSN1/BCL6/IRF1/SPN/RUNX3/PAWR/DLG5/INPP5D/DLG1/GLI3/ID2/MDK/PKN1	44
GO:0030218	erythrocyte differentiation	37/2053	120/18722	2.83505686655149e-09	1.17312697926269e-07	ISG15/ZFP36/SPI1/NCKAP1L/MAFB/LYN/B2M/JAK2/VEGFA/KLF2/HMGB2/STAT1/PRKDC/RPS14/SLC25A5/BCL6/ZFP36L1/IKZF1/SH2B3/RPS19/EPAS1/FAM210B/STAT3/GATA3/RPS6/CDK6/HCLS1/INPP5D/KMT2E/HSPA1A/ID2/TGFBR3/SMAD5/HSPA9/MAPK14/RCOR1/NCAPG2	37
GO:0071897	DNA biosynthetic process	48/2053	180/18722	3.17280190395282e-09	1.30389119340527e-07	DUSP1/KLF4/PCNA/TYMS/ARRB2/HSP90AA1/HSP90AB1/PKIB/CENPF/PTK2B/RFC3/HNRNPA1/RFC4/TK1/RFC2/GJA1/DTL/LIG1/SPHK1/NHP2/RFC1/USP10/POLD3/RGCC/HNRNPD/TCP1/DSCC1/CCT6A/POLE3/CCT2/XRCC5/RAD50/PNKP/TFDP1/PHB/RPA1/HNRNPA2B1/POLA1/POLD4/CDKN1A/CCT4/AURKB/POLQ/POLD2/VCP/CCT8/MAP3K4/POLE2	48
GO:0051701	biological process involved in interaction with host	52/2053	203/18722	3.27267458389879e-09	1.32833483264818e-07	HLA-DRB1/LGALS1/CD74/CXCR4/FCN1/IFITM2/LGALS9/CD86/TRIM22/CTSB/IFITM3/EGFR/ITGA5/CTSL/CD4/TNFRSF14/IFIT1/CLEC5A/P4HB/SIVA1/RPSA/SELPLG/CD46/DAG1/BSG/CIITA/CDK1/ITGB1/PPIA/DPP4/ICAM1/SIGLEC1/PHB2/CXCL8/DDB1/NRP1/ITGB5/SLC1A5/ANPEP/TCP1/ITGAV/PLSCR1/TRIM38/PHB/SLC52A1/HSPA1A/TFRC/CHMP4C/INSR/TRIM28/SLC3A2/DYNLT1	52
GO:0019079	viral genome replication	39/2053	131/18722	3.27655925386551e-09	1.32833483264818e-07	BST2/IFITM2/APOBEC3A/ISG15/MX1/OAS2/IFITM3/OASL/IFIT1/HACD3/IFI16/TNF/ISG20/DEK/PABPC1/TOP2A/NUCKS1/PPIA/NOTCH1/PPIB/RSAD2/OAS1/IFI27/CXCL8/HSPA8/APOBEC3G/APOBEC3C/DDB1/STAU1/PLSCR1/PHB/HTATSF1/SRPK1/EIF2AK4/TOP2B/ATG16L2/TRIM28/VCP/EEA1	39
GO:0007249	I-kappaB kinase/NF-kappaB signaling	65/2053	281/18722	3.48951462374131e-09	1.39994848441696e-07	HLA-DRB1/LGALS1/CD74/BST2/S100A4/TNFSF10/LGALS9/CLEC7A/MTDH/FLNA/PYCARD/TRIM22/TLR2/S100A12/LILRB4/SECTM1/CD4/HACD3/CASP1/TNF/TNFAIP3/TLR4/IL1B/CD36/GSTP1/STAT1/HMOX1/WLS/PRDX4/BTK/TGM2/TLR6/TLR7/NFKBIA/TMED4/CARD16/LITAF/TREM2/PRKCB/GJA1/CX3CR1/TLR8/NLRP12/BIRC3/CXXC5/RHOA/USP10/APOL3/BRD4/SIRPA/MYD88/SLC20A1/TRIM38/ECT2/DDX1/TLE1/FKBP1A/TFRC/REL/PLK2/SLC44A2/UBE2N/S100A13/TFG/GAPDH	65
GO:0007015	actin filament organization	90/2053	441/18722	3.52394605671272e-09	1.39994848441696e-07	AIF1/TMSB4X/GMFG/CORO1A/MARCKS/PLEK/LCP1/NCKAP1L/FLNA/PHACTR1/CAPG/PYCARD/WAS/WIPF1/COTL1/MYO1F/HCK/RAC2/MYO1G/GPR65/TMSB10/JAK2/STMN1/HSP90B1/MYADM/ARPC3/VASP/PTGER4/PDLIM1/MET/CALD1/PREX1/PSTPIP1/ARPC5L/DIAPH3/DSTN/PTK2B/EMP2/ARHGAP25/ICAM1/IQGAP2/ID1/RASA1/RHOBTB3/CCDC88A/KANK1/TACSTD2/S100A10/FAT1/ALDOA/PAWR/RDX/NRP1/RHOA/ACTR2/TPM3/ITGB5/KANK4/RGCC/ZYX/TWF2/MYO1C/GRB2/SCIN/SPTBN1/TJP1/ARPC4/FERMT2/ACTR3/ARPC1A/WASF2/PFN1/RHOG/HCLS1/EPS8/SLC9A1/BCAR1/ARHGEF2/EZR/CORO1C/DLG1/RHOB/CD2AP/LIMA1/MYO5A/TRIOBP/CFL1/COBL/RAC3/MYO7A	90
GO:0002449	lymphocyte mediated immunity	76/2053	350/18722	3.53100045522754e-09	1.39994848441696e-07	HLA-B/FCER1G/HLA-A/HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/HLA-DMA/CD74/CORO1A/HLA-F/TNFRSF1B/HLA-DQB1/HLA-DMB/LGALS9/HLA-DQA1/TGFB1/NCKAP1L/WAS/HLA-DQA2/B2M/HLA-E/HAVCR2/LILRB1/LILRB4/MYO1G/HMGB1/TUBB/HLA-DRB5/TNF/HSPD1/SLAMF7/IL1B/GAPT/IRF7/CCR2/ARRB2/SASH3/C3/CADM1/BTK/CTSH/STAT6/CD46/NLRP3/IL27RA/PTPN6/LYST/UNG/TUBB4B/CD1D/IL4I1/RSAD2/BCL6/TREM2/C1QA/VAV1/EMP2/ICAM1/MSH2/TLR8/C1QBP/MSH6/GATA3/MYD88/PRDX1/INPP5D/ERCC1/TCIRG1/RNF8/RIF1/TFRC/IL18/EXO1/SERPING1	76
GO:0052547	regulation of peptidase activity	93/2053	461/18722	3.5597866268876e-09	1.39994848441696e-07	LAPTM5/S100A8/TIMP1/SERPINA1/PSMB9/BST2/CD44/TNFSF10/LGALS9/CLEC7A/PSMB8/PYCARD/LYN/PLAUR/SORL1/CST3/FBLN1/ITIH5/FN1/HMGB1/SPINT1/GPX1/KLF4/SPINT2/JAK2/MBP/VEGFA/PERP/CASP1/IFI16/PEBP1/TNF/HSPD1/SERPINF1/APP/GRN/ARRB2/C3/RPS3/CTSH/CTSD/PRDX5/SYK/NLRP3/CLDN4/CARD16/APLP2/TIMP2/S100A9/IFI6/TIMP3/CRIM1/CST6/HSPE1/NR4A1/DHCR24/PSME2/AIM2/SERPINH1/NAIP/CSTB/BIRC5/NLRP12/ASPH/BIRC3/PCOLCE2/PMAIP1/PSMA3/RHOA/TRIAP1/SIAH2/NLRP1/RPS6KA1/STAT3/PRDX3/BCL2L12/PDCD5/PSMD14/CSTA/EFNA1/USP14/CASP8AP2/FIS1/PARK7/BAD/SERPINB8/VCP/PICALM/NDUFA13/SERPING1/GAPDH/PPARG/GPC3	93
GO:0050729	positive regulation of inflammatory response	41/2053	142/18722	3.56986863526323e-09	1.39994848441696e-07	S100A8/CCL3/GPSM3/HLA-E/TLR2/S100A12/EGFR/ALOX5AP/JAK2/LRRK2/NEAT1/TNF/TLR4/HSPD1/IL1B/APP/CEBPB/GRN/CCR2/PTGER4/C3/BTK/TGM2/TLR7/NFKBIA/LILRA5/S100A9/TREM2/PLA2G7/ADAM8/IL16/NLRP12/RPS19/IFI35/IL6ST/SNX4/IL17RA/NFKBIZ/PARK7/MDK/IL18	41
GO:0002224	toll-like receptor signaling pathway	37/2053	121/18722	3.65675831659269e-09	1.42471103243871e-07	CTSS/CD14/CYBA/LYN/LY96/PIK3AP1/HAVCR2/TLR2/CD300A/SCIMP/HMGB1/TLR1/TNFAIP3/IRAK3/TLR4/COLEC12/HSPD1/CD36/CD300LF/IRF7/ARRB2/LILRA2/BTK/TLR6/TLR7/NFKBIA/RSAD2/TREM2/IRF1/OAS1/TLR8/BIRC3/IFI35/UNC93B1/MAPKAPK3/MYD88/LGR4	37
GO:0030217	T cell differentiation	61/2053	257/18722	3.70701571089394e-09	1.43497382357185e-07	FCER1G/HLA-DRA/PTPRC/HLA-DRB1/FGL2/CD74/SPI1/LGALS9/NCKAP1L/MAFB/ZFP36L2/CD86/LILRB2/B2M/CD83/LILRB4/HMGB1/CTSL/CD4/PRDX2/IL1B/CCR2/PTGER4/RUNX1/DOCK2/SASH3/PRKDC/STAT6/CD46/PREX1/SYK/NLRP3/SOD1/RARA/SEMA4A/CD1D/IL4I1/RSAD2/BCL6/ZFP36L1/LFNG/ADAM8/IL6R/VAV1/IRF1/GPR183/SPN/RUNX3/RHOA/STAT3/SOX4/PNP/GATA3/RPS6/NFKBIZ/BAD/TCIRG1/GLI3/MDK/IL18/FANCA	61
GO:0050671	positive regulation of lymphocyte proliferation	40/2053	137/18722	3.86970943838032e-09	1.48834978399243e-07	HLA-A/AIF1/HLA-DPA1/HLA-DPB1/PTPRC/CD74/CORO1A/TNFSF13B/HLA-DMB/LGALS9/NCKAP1L/PYCARD/CD86/LILRB2/HLA-E/HAVCR2/MEF2C/HMGB1/TLR4/IL1B/CCR2/SASH3/RPS3/CD24/CD46/SYK/IL27RA/CD1D/BCL6/GPR183/SLC39A10/CCDC88B/PNP/IL6ST/MYD88/VAV3/CDKN1A/TFRC/IL18/CD320	40
GO:0036230	granulocyte activation	20/2053	43/18722	4.55636325833939e-09	1.74128532165837e-07	TYROBP/FCER1G/ITGB2/CCL3/SPI1/CD300A/ITGAM/PTAFR/GRN/STXBP2/CCR2/PRAM1/LILRA2/PREX1/SYK/CXCL8/MYD88/ANXA3/KMT2E/IL18	20
GO:0002396	MHC protein complex assembly	13/2053	19/18722	4.5863125839921e-09	1.74163769012358e-07	HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DMB/HLA-DQA1/HLA-DQA2/B2M/HLA-DRB5/CALR/TAPBP	13
GO:0032946	positive regulation of mononuclear cell proliferation	40/2053	138/18722	4.87870968079154e-09	1.84102252105341e-07	HLA-A/AIF1/HLA-DPA1/HLA-DPB1/PTPRC/CD74/CORO1A/TNFSF13B/HLA-DMB/LGALS9/NCKAP1L/PYCARD/CD86/LILRB2/HLA-E/HAVCR2/MEF2C/HMGB1/TLR4/IL1B/CCR2/SASH3/RPS3/CD24/CD46/SYK/IL27RA/CD1D/BCL6/GPR183/SLC39A10/CCDC88B/PNP/IL6ST/MYD88/VAV3/CDKN1A/TFRC/IL18/CD320	40
GO:0042129	regulation of T cell proliferation	46/2053	171/18722	4.97086381779422e-09	1.86407393167283e-07	HLA-A/AIF1/HLA-DPA1/HLA-DPB1/PTPRC/HLA-DRB1/CORO1A/TNFSF13B/TNFRSF1B/HLA-DMB/LGALS9/NCKAP1L/PYCARD/CD86/LILRB2/HLA-E/HAVCR2/LILRB1/LILRB4/RAC2/HMGB1/TNFRSF14/IL1B/CEBPB/CCR2/SASH3/RPS3/CD24/GPNMB/CD46/SYK/IL27RA/PTPN6/LGALS3/CD1D/IL4I1/IRF1/SPN/PAWR/CCDC88B/PNP/IL6ST/DLG5/DLG1/TFRC/IL18	46
GO:0002821	positive regulation of adaptive immune response	35/2053	112/18722	5.09163354820999e-09	1.89750318566832e-07	HLA-B/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/SLC11A1/TNFSF13B/HLA-F/CLEC7A/TGFB1/PYCARD/B2M/HLA-E/CD4/TNF/HSPD1/IL1B/CCR2/SASH3/C3/BTK/STAT6/NLRP3/IL27RA/CD1D/RSAD2/TREM2/MSH2/IL6ST/GATA3/EIF2AK4/NFKBIZ/RIF1/TFRC/IL18	35
GO:0042113	B cell activation	73/2053	334/18722	5.34944624938984e-09	1.9812763886629e-07	TYROBP/LAPTM5/MNDA/PTPRC/LGALS1/CD74/BST2/TNFSF13B/SPI1/TGFB1/NCKAP1L/LYN/ZFP36L2/LAT2/CD86/MEF2C/CD300A/THEMIS2/KLF6/LYL1/DOCK10/TNFAIP3/TLR4/HSPD1/ITGA4/GAPT/IRF8/SASH3/PRKDC/BTK/STAT6/SYK/IL27RA/PTPN6/SLC25A5/ITGB1/UNG/IL4I1/SAMSN1/HHEX/BCL6/ZFP36L1/LFNG/NFAM1/PTK2B/GPR183/SLC39A10/SKAP2/PRKCB/MFNG/PHB2/EZH2/MSH2/CD180/PAWR/MSH6/NOTCH2/PHB/INPP5D/VAV3/ERCC1/BAD/CDKN1A/TCIRG1/RNF8/RIF1/ID2/TFRC/DOCK11/EXO1/PKN1/DNAJB9/CD320	73
GO:0000280	nuclear division	89/2053	439/18722	6.02594900103334e-09	2.21814073657669e-07	FLNA/DUSP1/IL1B/RANBP1/TOP2A/RAN/MKI67/PRC1/BMP7/SMC2/RAD51AP1/CENPF/ZWINT/SMC3/NUSAP1/CALR/MAD2L1/RAD51/CDC6/CCNE1/ANAPC11/PHB2/ASPM/SMC4/UBE2C/UBB/CHEK1/CDT1/RAD51C/KPNB1/CENPK/CKS2/SPHK1/RHOA/ACTR2/CDCA5/KIF23/PKMYT1/FBXO5/RAD21/CCNE2/UBE2S/NUF2/MND1/TPX2/NCAPD3/NCAPH/RGCC/AURKAIP1/DSCC1/LRP5/MYBL2/BUB3/ANLN/BRCA2/KIF20B/TPR/FANCD2/RAD50/KIF22/PSMC3IP/ACTR3/NDC80/EML4/OBSL1/KMT5A/EPS8/STAG1/TTK/DSN1/NCAPG/HSPA1A/TOP2B/NUDC/ING2/AURKB/LCMT1/CHMP4C/INSR/KIF4A/DRG1/CDCA8/BUB1B/KIF11/KNTC1/FIGNL1/FANCA/NCAPG2/KIFC1	89
GO:0042119	neutrophil activation	18/2053	36/18722	6.33026728120257e-09	2.3159514443424e-07	TYROBP/FCER1G/ITGB2/SPI1/CD300A/ITGAM/PTAFR/GRN/STXBP2/PRAM1/LILRA2/PREX1/SYK/CXCL8/MYD88/ANXA3/KMT2E/IL18	18
GO:0051090	regulation of DNA-binding transcription factor activity	89/2053	440/18722	6.75909045355937e-09	2.45785107402159e-07	S100A8/TMSB4X/SPI1/LGALS9/CLEC7A/MTDH/FLNA/PYCARD/HAVCR2/TRIM22/TLR2/S100A12/HCK/KLF4/JAK2/VEGFA/PRDX2/TNF/TNFAIP3/IRAK3/TLR4/IL1B/CD36/APP/HMOX1/SGK1/ARRB2/RPS3/BTK/TLR6/NFKBIA/SYK/CAMK1D/NLRP3/CARD16/BMP7/PPIA/S100A9/NPM1/ADAM8/NFAM1/AIM2/ICAM1/ID1/PRKCB/PHB2/EZH2/CX3CR1/NLRP12/NLRC5/TRIB1/CHP1/SPHK1/CIB1/STAT3/HDAC2/RGCC/PRDX3/LRP5/BHLHE40/PLPP3/MYD88/ID3/NFKBIE/CDKN2A/TRIM38/TFDP1/ANXA3/SP100/EIF2AK4/ARID5B/COMMD7/HCLS1/PARK7/ARHGEF2/COMMD1/HSPA1A/DDX58/TAX1BP1/ID2/TFRC/RTKN2/RPS6KA5/UBE2N/IL18/PURA/COMMD6/FANCA/PPARG	89
GO:0006801	superoxide metabolic process	27/2053	74/18722	6.88567996463172e-09	2.48879998721628e-07	TYROBP/ITGB2/CYBB/NCF2/CYBA/NCF1/CLEC7A/TGFB1/EGFR/SOD2/ITGAM/PRDX2/CD36/GSTP1/HVCN1/PREX1/SYK/SOD1/BMP7/DHFR/NCF4/GNAI2/PRDX1/ACP5/CYB5R4/SOD3/GCH1	27
GO:0002253	activation of immune response	79/2053	375/18722	7.36304906033772e-09	2.64540684802553e-07	TYROBP/FCER1G/HLA-A/LAPTM5/HLA-DPB1/MNDA/PTPRC/HLA-DRB1/FCN1/FPR1/HLA-DQB1/CLEC7A/NCKAP1L/PYCARD/C5AR1/LYN/FPR3/LAT2/MEF2C/C3AR1/CFD/CD300A/HCK/LILRB4/MYO1G/HMGB1/CFP/THEMIS2/FGR/IFI16/TLR4/IL1B/GBP1/LCP2/PRAM1/C3/RPS3/PRKDC/LILRA2/BTK/CD46/HSP90AA1/SYK/PTPN6/CSK/LGALS3/TREM2/C1QA/VAV1/NFAM1/CD59/AIM2/SLC39A10/CMTM3/PRKCB/PAWR/C1QBP/HRAS/RGCC/GATA3/PLSCR1/KCNN4/XRCC5/RAP1A/PHB/STOML2/NFKBIZ/XRCC6/BCAR1/INPP5D/PHPT1/EZR/VAV3/BTN3A1/YES1/PTK2/UBE2N/PLEKHA1/SERPING1	79
GO:0048285	organelle fission	96/2053	488/18722	7.62047642528376e-09	2.72159872331563e-07	FLNA/DUSP1/LRRK2/IL1B/RANBP1/TOP2A/RAN/MKI67/PRC1/BMP7/SMC2/RAD51AP1/CENPF/ZWINT/SMC3/NUSAP1/CALR/MAD2L1/RAD51/CDC6/CCNE1/ANAPC11/PHB2/ASPM/SMC4/UBE2C/UBB/CHEK1/CDT1/RAD51C/KPNB1/CENPK/CKS2/SPHK1/STAT2/RHOA/ACTR2/CDCA5/KIF23/PKMYT1/FBXO5/RAD21/CCNE2/UBE2S/NUF2/MND1/TPX2/NCAPD3/NCAPH/RGCC/AURKAIP1/DSCC1/LRP5/MYBL2/BUB3/ANLN/BRCA2/KIF20B/TPR/FANCD2/RAD50/KIF22/PSMC3IP/ACTR3/NDC80/EML4/OBSL1/INF2/FIS1/KMT5A/EPS8/STAG1/TTK/DSN1/NCAPG/CORO1C/HSPA1A/TOP2B/BNIP3/NUDC/ING2/AURKB/LCMT1/CHMP4C/INSR/KIF4A/DRG1/CDCA8/BUB1B/KIF11/KNTC1/FIGNL1/FANCA/PPARG/NCAPG2/KIFC1	96
GO:0000819	sister chromatid segregation	51/2053	202/18722	7.83278546438728e-09	2.78087057907241e-07	DUSP1/FEN1/TOP2A/RAN/PRC1/SMC2/CENPF/ZWINT/SMC3/NUSAP1/MAD2L1/CDC6/ANAPC11/RMI2/PHB2/SMC4/UBE2C/CDT1/RAD51C/KPNB1/CENPK/CDCA5/KIF23/FBXO5/RAD21/NUF2/NCAPD3/NCAPH/DSCC1/BUB3/ESCO2/TPR/KIF22/NDC80/EML4/KMT5A/STAG1/TTK/DSN1/NCAPG/TOP2B/NUDC/AURKB/LCMT1/CHMP4C/KIF4A/CDCA8/BUB1B/KNTC1/NCAPG2/KIFC1	51
GO:0002286	T cell activation involved in immune response	35/2053	114/18722	8.53684552019796e-09	3.01300430124634e-07	FCER1G/HLA-DRA/HLA-DRB1/FGL2/CD74/SLC11A1/LCP1/HLA-DMB/LGALS9/NCKAP1L/CD86/APBB1IP/HAVCR2/LILRB1/ITGAL/HMGB1/PTGER4/STAT6/CD46/NLRP3/RARA/LGALS3/SEMA4A/BCL6/IL6R/GPR183/SPN/ICAM1/STAT3/GATA3/RPS6/EIF2AK4/NFKBIZ/MDK/IL18	35
GO:2000377	regulation of reactive oxygen species metabolic process	43/2053	157/18722	8.69853837819527e-09	3.05211872919132e-07	TYROBP/TSPO/ITGB2/CYBA/CLEC7A/TGFB1/PAGE4/RAC2/EGFR/SOD2/ITGAM/ALOX5/PRDX2/TNF/TLR4/HSPD1/CD36/GSTP1/HVCN1/TLR6/SYK/SOD1/BMP7/PTK2B/DHFR/HK2/BRCA1/GNAI2/DCXR/TFAP2A/RHOA/STAT3/STK17A/GRB2/ACP5/VDAC1/PARK7/GCH1/CDKN1A/BNIP3/TRAP1/FOXM1/MAPK14	43
GO:0045621	positive regulation of lymphocyte differentiation	33/2053	104/18722	9.05461891076338e-09	3.15858799212676e-07	HLA-DRA/PTPRC/HLA-DRB1/CD74/LGALS9/NCKAP1L/CD86/LILRB2/CD83/LILRB4/RUNX1/SASH3/PRKDC/BTK/CD46/SYK/NLRP3/RARA/IL4I1/BCL6/ADAM8/RUNX3/RHOA/SOX4/PNP/GATA3/NFKBIZ/XRCC6/INPP5D/BAD/GLI3/MDK/IL18	33
GO:1904951	positive regulation of establishment of protein localization	70/2053	319/18722	9.24572062605224e-09	3.20660830961349e-07	HLA-DRB1/ITGB2/TGFB1/FLNA/SORL1/TLR2/RAC2/EGFR/JAK2/ITGAM/TCAF1/CDH1/OAZ1/TNF/TLR4/IL1B/MYH10/WLS/PLK3/GLUL/RAN/HSP90AB1/CAMK1/MPC2/CDK1/SERP1/PPIA/TREM2/ADAM8/CD33/GJA1/HRAS/CHP1/TRPM2/ISL1/CIB1/FRMD4A/SOX4/TCP1/ACSL4/CCT6A/PDCD5/MYO1C/ANK3/KIF20B/TMEM30B/TPR/KCNN4/CCT2/SAE1/FIS1/YWHAE/HCLS1/ECT2/PHPT1/EZR/BAD/NMT1/IPO5/CCT4/CD2AP/CENPJ/GLI3/TRIM28/B3GAT3/CCT8/CTDSPL2/HUWE1/TM7SF3/MAPK14	70
GO:0051235	maintenance of location	71/2053	326/18722	1.00929246345908e-08	3.48031883951405e-07	S100A8/SRGN/TSPO/TMSB4X/PTPRC/CORO1A/CCL3/CYBA/MSR1/FLNA/LYN/SORL1/FTH1/FTL/SLC8A1/TMSB10/FBN2/CD4/FBN1/HSP90B1/TNF/IL1B/CD36/CXCL10/C3/NFKBIA/MEST/PTPN6/S100A9/CALR/TREM2/PTK2B/HSPA5/HILPDA/HK2/PLIN2/ASPM/CCDC88A/GJA1/CAMK2D/GPAA1/TRPM2/BARD1/LTBP1/CALM2/SQLE/TXN/MCOLN3/ARL2/ITGAV/TWF2/ANK3/SCIN/NFKBIE/GOPC/CHCHD10/SP100/VPS13C/PARK7/ARHGAP21/DMD/GAA/CDS1/FKBP1A/UBASH3B/AKAP9/HEXB/GPSM2/KDELR2/ASXL1/PPARG	71
GO:1903829	positive regulation of cellular protein localization	63/2053	276/18722	1.04435378525025e-08	3.58064154942944e-07	TYROBP/ITGB2/MSN/TGFB1/FLNA/SORL1/RAC2/EGFR/JAK2/ITGAM/TCAF1/CDH1/TNF/PARP1/RAN/HSP90AB1/CDK1/ITGB1/LGALS3/PARP9/TREM2/NPM1/CCDC88A/CDT1/HRAS/CHP1/RDX/CIB1/TCP1/CCT6A/PDCD5/MYO1C/ANK3/TPR/CCT2/SPTBN1/YAP1/FERMT2/NDC80/DTX3L/GNL3/GNAI1/SAE1/RHOG/FIS1/HCLS1/PARK7/ECT2/EZR/DLG1/NMT1/IPO5/CCT4/CD2AP/GLI3/TFRC/TRIM28/CCT8/PTN/GPSM2/HUWE1/EPB41/MAPK14	63
GO:0000723	telomere maintenance	38/2053	131/18722	1.14632844496956e-08	3.90793788057803e-07	PCNA/PARP1/PRKDC/RPA3/FEN1/HSP90AA1/HSP90AB1/PKIB/RAD51/CCNE1/HNRNPA1/RPA2/RAD51C/NHP2/RFC1/CCNE2/BLM/HNRNPD/TCP1/CCT6A/BRCA2/CCT2/XRCC5/RAD50/PNKP/GNL3/RPA1/SP100/XRCC6/HNRNPA2B1/APEX1/ERCC1/CCT4/AURKB/RIF1/CCT8/MAP3K4/EXO1	38
GO:0046849	bone remodeling	30/2053	90/18722	1.18014942635753e-08	4.00050653002553e-07	CSF1R/TGFB1/RAC2/EGFR/SPP1/SNX10/TNFAIP3/SYK/CSK/ADAM8/PTK2B/PDK4/HAMP/P2RX7/GJA1/TPP1/SYT7/NOTCH2/LRP5/LGR4/RAB3D/ACP5/RASSF2/INPP5D/TCIRG1/TFRC/MDK/UBASH3B/PTN/SUCO	30
GO:0044786	cell cycle DNA replication	19/2053	41/18722	1.19680071136978e-08	4.03415970124643e-07	PCNA/GMNN/MCM3/MCM6/FEN1/BCL6/RAD51/MCM4/CDT1/LIG1/MCM2/FBXO5/BLM/BRCA2/CDC45/DBF4/POLA1/TIPIN/E2F7	19
GO:0052548	regulation of endopeptidase activity	87/2053	432/18722	1.238062683421e-08	4.14993078241677e-07	LAPTM5/S100A8/TIMP1/SERPINA1/PSMB9/BST2/CD44/TNFSF10/LGALS9/CLEC7A/PSMB8/PYCARD/LYN/PLAUR/SORL1/CST3/ITIH5/HMGB1/SPINT1/GPX1/KLF4/SPINT2/JAK2/MBP/VEGFA/PERP/CASP1/IFI16/PEBP1/TNF/HSPD1/SERPINF1/APP/ARRB2/C3/RPS3/CTSH/CTSD/PRDX5/SYK/NLRP3/CARD16/APLP2/TIMP2/S100A9/IFI6/TIMP3/CRIM1/CST6/HSPE1/NR4A1/DHCR24/PSME2/AIM2/SERPINH1/NAIP/CSTB/BIRC5/NLRP12/ASPH/BIRC3/PMAIP1/PSMA3/RHOA/TRIAP1/SIAH2/NLRP1/RPS6KA1/STAT3/PRDX3/BCL2L12/PDCD5/PSMD14/CSTA/EFNA1/USP14/CASP8AP2/FIS1/PARK7/BAD/SERPINB8/VCP/PICALM/NDUFA13/SERPING1/GAPDH/PPARG	87
GO:0045860	positive regulation of protein kinase activity	80/2053	386/18722	1.2765027157748e-08	4.25500905258267e-07	PTPRC/SLC11A1/NCF1/FCGR1A/CSF1R/TGFB1/NCKAP1L/CD86/CD300A/S100A12/HMGB1/EGFR/JAK2/LRRK2/VEGFA/CD4/TNF/TLR4/IL1B/FGD2/LCP2/MAGED1/RPS3/CD24/TLR6/HSP90AA1/CLSPN/SYK/HSP90AB1/DAG1/CAMK1/CSK/LILRA5/CKS1B/PPIA/NPM1/ADAM8/IL6R/PTK2B/EMP2/CDC6/CCND1/RPLP1/PIK3R5/ERP29/PHB2/FLT1/EZH2/CCDC88A/HBEGF/DAZAP2/HRAS/CCND3/CKS2/RHOA/CALM2/CIB1/TPX2/TXN/RGCC/RALB/EFNA1/XRCC5/RAP1A/DBF4/FERMT2/PHB/XRCC6/RASSF2/PARK7/ECT2/DLG1/CDKN1A/STK4/INSR/MAP3K4/PTK2/PDGFA/IL18/PRKAG2	80
GO:0033674	positive regulation of kinase activity	92/2053	467/18722	1.45644330291373e-08	4.82798884943779e-07	PTPRC/HLA-DRB1/CD74/SLC11A1/NCF1/FCGR1A/CSF1R/TGFB1/NCKAP1L/LYN/CD86/CD300A/S100A12/HMGB1/EGFR/FGR/JAK2/LRRK2/VEGFA/CD4/TNF/TLR4/IL1B/FGD2/LCP2/MAGED1/RPS3/CD24/MET/TLR6/HSP90AA1/CLSPN/SYK/HSP90AB1/DAG1/CAMK1/CSK/LILRA5/CKS1B/PPIA/LMO4/TREM2/NPM1/ADAM8/IL6R/PTK2B/EMP2/CDC6/CCND1/RPLP1/PIK3R5/ERP29/PHB2/FLT1/EZH2/CCDC88A/HBEGF/DAZAP2/HRAS/CCND3/CKS2/RHOA/CALM2/CIB1/TPX2/TXN/RGCC/EPHB4/RALB/EFNA1/XRCC5/RAD50/RAP1A/DBF4/FERMT2/PHB/XRCC6/RASSF2/PARK7/ECT2/VAV3/DLG1/BAD/CDKN1A/IGF1R/STK4/INSR/MAP3K4/PTK2/PDGFA/IL18/PRKAG2	92
GO:0042116	macrophage activation	33/2053	106/18722	1.53823926910421e-08	5.07111846957431e-07	TYROBP/AIF1/PTPRC/ITGB2/CD74/CCL3/SLC11A1/CD84/C5AR1/HAVCR2/TLR2/HMGB1/JAK2/LRRK2/TLR1/ITGAM/TNF/TLR4/HSPD1/APP/NAMPT/GRN/TLR6/IFNGR2/SYK/CD93/TREM2/C1QA/HAMP/CX3CR1/SPHK1/IFI35/IFNGR1	33
GO:0034614	cellular response to reactive oxygen species	42/2053	155/18722	1.81413617154182e-08	5.94798744767808e-07	NCF1/FOS/KLF4/EGFR/SOD2/LRRK2/PCNA/KLF2/PRDX2/TNFAIP3/CD36/RPS3/BTK/MET/STAT6/PRDX5/SOD1/CDK1/BMP7/DHFR/EZH2/PAWR/TRPM2/SPHK1/HDAC2/TXN/PRDX3/SIRPA/PRDX1/NET1/SOD3/JUN/APEX1/PARK7/ECT2/GCH1/BNIP3/RHOB/TRAP1/KDM6B/SIGMAR1/PLEKHA1	42
GO:0032970	regulation of actin filament-based process	81/2053	396/18722	1.91849651583226e-08	6.25596689945303e-07	TMSB4X/GMFG/CORO1A/BST2/PLEK/CSF1R/ARHGDIB/NCKAP1L/FLNA/CAPG/PYCARD/WAS/COTL1/HCK/RAC2/GPR65/TMSB10/ABI3/STMN1/DSP/MYADM/ARPC3/VASP/PTGER4/CNN2/MET/PREX1/ARPC5L/DSTN/PTK2B/DSG2/ICAM1/IQGAP2/ID1/RASA1/RHOBTB3/CCDC88A/CAMK2D/KANK1/TACSTD2/S100A10/HRAS/RDX/GJA5/TRPM2/NRP1/DSC2/RHOA/ACTR2/NOTCH2/KANK4/RGCC/TWF2/MYO1C/GRB2/JAM3/SCIN/SPTBN1/TJP1/ARPC4/FERMT2/ACTR3/ARPC1A/WASF2/PFN1/RHOG/HCLS1/EPS8/RHOQ/SLC9A1/ECT2/PHPT1/DLG1/RHOB/CD2AP/LIMA1/MDK/AKAP9/TRIOBP/PDGFA/RAC3	81
GO:0071214	cellular response to abiotic stimulus	71/2053	331/18722	1.95246517096488e-08	6.29827474504801e-07	TSPO/TIMP1/CYBA/CRIP1/EGFR/PCNA/CASP1/IFI16/TLR4/ADIRF/PARP1/IL1B/PTAFR/NAMPT/SLC2A1/PTGER4/HVCN1/CNN2/RCSD1/TLR7/DAG1/CARD16/NUCKS1/MME/RAD51AP1/ENG/ZFP36L1/NPM1/LRRC8C/RAD51/HSPA5/IRF1/HAMP/GJA1/TLR8/PBK/CHEK1/AKR1B1/HRAS/CHP1/DDB1/TRIAP1/MAP3K2/BLM/POLD3/GATA3/GRB2/MYD88/XRCC5/YAP1/CASP8AP2/NET1/TMEM150C/GNA11/EIF2AK4/XRCC6/SLC9A1/ECT2/ARHGEF2/ERCC1/BAD/NMT1/CDKN1A/BNIP3/RHOB/EFHD1/AURKB/PTN/MAPK14/TMEM109/FIGNL1	71
GO:0104004	cellular response to environmental stimulus	71/2053	331/18722	1.95246517096488e-08	6.29827474504801e-07	TSPO/TIMP1/CYBA/CRIP1/EGFR/PCNA/CASP1/IFI16/TLR4/ADIRF/PARP1/IL1B/PTAFR/NAMPT/SLC2A1/PTGER4/HVCN1/CNN2/RCSD1/TLR7/DAG1/CARD16/NUCKS1/MME/RAD51AP1/ENG/ZFP36L1/NPM1/LRRC8C/RAD51/HSPA5/IRF1/HAMP/GJA1/TLR8/PBK/CHEK1/AKR1B1/HRAS/CHP1/DDB1/TRIAP1/MAP3K2/BLM/POLD3/GATA3/GRB2/MYD88/XRCC5/YAP1/CASP8AP2/NET1/TMEM150C/GNA11/EIF2AK4/XRCC6/SLC9A1/ECT2/ARHGEF2/ERCC1/BAD/NMT1/CDKN1A/BNIP3/RHOB/EFHD1/AURKB/PTN/MAPK14/TMEM109/FIGNL1	71
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	9/2053	10/18722	2.03516093362964e-08	6.52992812929296e-07	FGL2/HLA-DMB/LGALS9/APBB1IP/HAVCR2/LILRB1/ITGAL/LGALS3/ICAM1	9
GO:1901214	regulation of neuron death	69/2053	319/18722	2.17126723672107e-08	6.92957628740768e-07	TYROBP/ITGB2/CORO1A/CCL3/HLA-F/TNFRSF1B/C5AR1/SORL1/MEF2C/FOS/SOD2/JAK2/LRRK2/ITGAM/TNF/TLR4/NR4A2/HSPD1/PARP1/SERPINF1/HMOX1/CEBPB/GRN/ARRB2/GPNMB/TLR6/CTSZ/HSP90AB1/SOD1/TREM2/C1QA/ADAM8/PTK2B/DHCR24/NAIP/DDIT4/RASA1/PPT1/BTG2/SET/CX3CR1/NAE1/MSH2/UBB/MCL1/HRAS/TFAP2A/CHP1/TRPM2/NRP1/ISL1/RHOA/STAT3/PSMC1/GATA3/GCLM/MYBL2/PARP2/NENF/FIS1/JUN/PARK7/BAD/REL/MDK/PICALM/SIGMAR1/EIF4G1/XRCC2	69
GO:0046631	alpha-beta T cell activation	42/2053	156/18722	2.22256841941921e-08	7.05577276006098e-07	HLA-A/HLA-DRA/PTPRC/HLA-DRB1/LGALS9/NCKAP1L/CD86/HLA-E/LILRB1/CD83/CD300A/LILRB4/HMGB1/CTSL/TNFRSF14/CLEC4A/CCR2/PTGER4/RUNX1/DOCK2/SASH3/STAT6/SYK/NLRP3/RARA/SEMA4A/RSAD2/BCL6/IL6R/IRF1/GPR183/SPN/RUNX3/RHOA/STAT3/PNP/GATA3/STOML2/NFKBIZ/TCIRG1/GLI3/IL18	42
GO:0043299	leukocyte degranulation	26/2053	73/18722	2.33301646522006e-08	7.36742041648441e-07	ITGB2/CORO1A/CCL3/HLA-F/SPI1/LGALS9/NCKAP1L/CD84/LYN/LAT2/CD300A/HCK/RAC2/FGR/ITGAM/PTAFR/HMOX1/STXBP2/CCR2/ADGRE2/PRAM1/BTK/SYK/SNX4/ANXA3/S100A13	26
GO:0034599	cellular response to oxidative stress	64/2053	288/18722	2.3877657132021e-08	7.50083470115843e-07	AIF1/NCF1/PAGE4/FOS/GPX1/KLF4/EGFR/SOD2/JAK2/LRRK2/PCNA/KLF2/ALOX5/PRDX2/TNFAIP3/TLR4/NR4A2/PARP1/CD36/P4HB/HMOX1/RPS3/BTK/MET/TLR6/STAT6/PRDX5/SOD1/CDK1/BMP7/PPIA/TREM2/DHFR/GPX8/EZH2/MCL1/EPAS1/PAWR/TRPM2/STAU1/SPHK1/HDAC2/TXN/PRDX3/SIRPA/FUT8/PRDX1/MGST1/NET1/CHCHD2/SOD3/JUN/APEX1/PARK7/ECT2/GCH1/HSPA1A/PYCR2/BNIP3/RHOB/TRAP1/KDM6B/SIGMAR1/PLEKHA1	64
GO:0006271	DNA strand elongation involved in DNA replication	11/2053	15/18722	2.41137875636415e-08	7.53555861363797e-07	PCNA/MCM7/MCM3/RFC3/MCM4/RFC4/LIG1/POLD3/POLE3/POLA1/POLD2	11
GO:0002833	positive regulation of response to biotic stimulus	44/2053	168/18722	2.54773750624478e-08	7.88679142562759e-07	TYROBP/MNDA/HLA-DRB1/FCN1/CYBA/HLA-F/SPI1/CLEC7A/PYCARD/LYN/LY96/HLA-E/HAVCR2/HCK/GBP5/SCIMP/HMGB1/LY86/OASL/IFI16/TLR4/HMGB2/HSPD1/GRN/IRF7/CADM1/PRKDC/LILRA2/HSP90AA1/SYK/CD1D/PARP9/ADAM8/VAV1/AIM2/TLR8/RPS19/CD180/NLRC5/IFI35/USP15/PLSCR1/XRCC5/XRCC6	44
GO:0071900	regulation of protein serine/threonine kinase activity	75/2053	359/18722	2.55006256095292e-08	7.88679142562759e-07	CSF1R/TGFB1/PYCARD/LYN/SORL1/SLC8A1/CD300A/S100A12/DUSP1/ACTB/EGFR/LRRK2/VEGFA/TNF/TNFAIP3/IRAK3/TLR4/IL1B/GSTP1/FGD2/MAGED1/RPS3/CD24/TLR6/SYK/HSP90AB1/CAMK1/PTPN6/CSK/BMP7/CKS1B/PKIB/HHEX/NR2F2/ADAM8/PTK2B/SH2B3/CDC6/CCND1/CCNE1/PIK3R5/ERP29/FLT1/CDKN1C/EZH2/DAZAP2/HRAS/TRIB1/CCND3/CKS2/RHOA/CALM2/CIB1/CCNA2/PKMYT1/CCNE2/BLM/RGCC/LRP5/RALB/CDKN2A/DBF4/FERMT2/RGS2/CCNI/CDKN1A/IPO5/IPO7/HERC5/STK4/INSR/MAP3K4/PDGFA/PRKAG2/PPARG	75
GO:0045619	regulation of lymphocyte differentiation	45/2053	174/18722	2.68564414129172e-08	8.26352043474376e-07	HLA-DRA/PTPRC/HLA-DRB1/FGL2/CD74/LGALS9/NCKAP1L/ZFP36L2/CD86/LILRB2/CD83/LILRB4/HMGB1/PRDX2/CCR2/RUNX1/SASH3/PRKDC/BTK/CD46/SYK/NLRP3/SOD1/PTPN6/RARA/IL4I1/BCL6/ZFP36L1/ADAM8/NFAM1/IRF1/RUNX3/RHOA/SOX4/PNP/GATA3/NFKBIZ/XRCC6/INPP5D/BAD/GLI3/ID2/MDK/IL18/FANCA	45
GO:0002367	cytokine production involved in immune response	31/2053	98/18722	2.74439393773861e-08	8.4012059318529e-07	HLA-A/LAPTM5/CD74/BST2/HLA-F/TNFRSF1B/CLEC7A/TGFB1/B2M/HLA-E/LILRB1/LILRB4/SCIMP/TNFRSF14/TNF/IRAK3/TLR4/TREM1/IL1B/CD36/HMOX1/CCR2/SASH3/BTK/NLRP3/RSAD2/BCL6/GATA3/DDX1/DDX58/IL18	31
GO:0042542	response to hydrogen peroxide	40/2053	146/18722	2.81438701768952e-08	8.57173710971426e-07	TXNIP/SLC8A1/DUSP1/GPX1/KLF4/SOD2/LRRK2/PCNA/KLF2/TNFAIP3/HSPD1/STAT1/HMOX1/RPS3/MET/STAT6/SOD1/CDK1/PTK2B/EZH2/PAWR/TRPM2/SPHK1/LDHA/HDAC2/TXN/PRDX3/SIRPA/NET1/JUN/APEX1/PARK7/ECT2/BAD/BNIP3/RHOB/TRAP1/KDM6B/SIGMAR1/PLEKHA1	40
GO:0002283	neutrophil activation involved in immune response	12/2053	18/18722	2.88773530613923e-08	8.70673961650018e-07	TYROBP/FCER1G/ITGB2/SPI1/ITGAM/PTAFR/STXBP2/PRAM1/LILRA2/SYK/MYD88/ANXA3	12
GO:0002501	peptide antigen assembly with MHC protein complex	12/2053	18/18722	2.88773530613923e-08	8.70673961650018e-07	HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DMB/HLA-DQA1/HLA-DQA2/B2M/HLA-DRB5/CALR	12
GO:0043254	regulation of protein-containing complex assembly	85/2053	427/18722	3.1596917528751e-08	9.47907525862531e-07	TMSB4X/GMFG/CORO1A/MSN/PLEK/ISG15/LCP1/CLEC7A/TGFB1/NCKAP1L/CAPG/PYCARD/WAS/SORL1/COTL1/HCK/GBP5/HMGB1/TMSB10/STMN1/VEGFA/TNF/TLR4/PARP1/CD36/MYADM/ARPC3/VASP/PTGER4/RPS3/MET/TLR6/HSP90AA1/PREX1/SYK/ARPC5L/LGALS3/LMO4/TREM2/PTK2B/HSPA5/LDLRAD4/ICAM1/IQGAP2/RASA1/KANK1/HSPA8/CDT1/CLIP1/RPL13A/FERMT1/RDX/ISL1/RHOA/ACTR2/KANK4/ARL2/TWF2/MYO1C/RALB/GRB2/JAM3/MYD88/SCIN/SPTBN1/ARPC4/SVIP/FERMT2/ACTR3/ARPC1A/WASF2/PFN1/HCLS1/EPS8/PARK7/DLG1/HSPA1A/LCMT1/TFRC/VCP/AKAP9/TRIOBP/DRG1/EIF4G1/MPP7	85
GO:0002437	inflammatory response to antigenic stimulus	26/2053	74/18722	3.22375938579674e-08	9.62316234566191e-07	CD68/HLA-DRB1/LYN/HLA-E/HCK/HMGB1/GPX1/FGR/TNF/HMGB2/IL1RN/C3/BTK/SYK/NOTCH1/TREM2/ICAM1/RHBDF2/CYSLTR1/NOTCH2/GATA3/PARK7/YES1/KDM6B/PLK2/MAPK14	26
GO:1900180	regulation of protein localization to nucleus	38/2053	136/18722	3.49784380217391e-08	1.03896350559621e-06	TGFB1/FLNA/LILRB4/RASSF5/JAK2/CDH1/PARP1/CD36/MAGED1/GLUL/RAN/HSP90AB1/CDK1/PARP9/NPM1/FERMT1/CHP1/TRIM29/TCP1/CCT6A/TPR/CCT2/YAP1/FERMT2/DTX3L/HCLS1/PARK7/ECT2/IPO5/CCT4/CD2AP/GLI3/TFRC/TRIM28/CCT8/LMNA/NUP54/MAPK14	38
GO:0002444	myeloid leukocyte mediated immunity	31/2053	99/18722	3.57946406787128e-08	1.05796967523289e-06	TYROBP/ITGB2/CCL3/SPI1/LGALS9/CD84/LYN/LAT2/HLA-E/CD300A/RAC2/FGR/ITGAM/TREM1/PTAFR/HMOX1/STXBP2/CCR2/ADGRE2/PRAM1/C3/BTK/SYK/CX3CR1/SNX4/MYD88/ANXA3/KMT2E/DDX1/DDX58/S100A13	31
GO:0070371	ERK1 and ERK2 cascade	70/2053	330/18722	3.92631047647677e-08	1.15479719896375e-06	PTPRC/CCL3L3/HLA-DRB1/CD74/CCL3/CD44/CSF1R/CCL4/LGALS9/TGFB1/PYCARD/C5AR1/LYN/ZFP36L2/HAVCR2/FBLN1/DUSP1/FN1/SCIMP/HMGB1/KLF4/EGFR/CD4/CCR1/TNF/TLR4/DUSP9/IL1B/CD36/GSTP1/APP/GBP1/PTGER4/ARRB2/GPNMB/GLIPR2/CTSH/GPBAR1/SYK/PTPN6/CSK/CDK1/NOTCH1/TIMP3/ZFP36L1/TREM2/PTK2B/MARCO/GPR183/ICAM1/SEMA6A/RRAS/PHB2/NLRP12/TPBG/GNAI2/HRAS/NRP1/CIB1/NOTCH2/ITGAV/SIRPA/RAP1A/FERMT2/PHB/EZR/DLG1/ATF3/EIF3A/PDGFA	70
GO:0010212	response to ionizing radiation	40/2053	148/18722	4.24795228656107e-08	1.23726765627992e-06	PTPRC/CYBA/GPX1/IFI16/PARP1/RRM1/NAMPT/CXCL10/PRKDC/NUCKS1/RAD51AP1/RAD51/HSPA5/HAMP/ICAM1/CCND1/BRCA1/MSH2/HRAS/TOPBP1/BLM/GATA3/GRB2/BRCA2/FANCD2/XRCC5/YAP1/NET1/XRCC6/ECT2/ERCC1/CDKN1A/RHOB/RNF8/BRCC3/MAPK14/TMEM109/FIGNL1/ALAD/XRCC2	40
GO:0097530	granulocyte migration	40/2053	148/18722	4.24795228656107e-08	1.23726765627992e-06	FCER1G/S100A8/CCL3L3/ITGB2/CD74/CCL3/CSF1R/CCL4/PECAM1/NCKAP1L/C5AR1/C3AR1/CD300A/S100A12/RAC2/TREM1/PTGER4/ADGRE2/CXCL10/PREX1/SYK/CAMK1D/BSG/JAML/PPIA/LGALS3/DPP4/S100A9/PPIB/ADAM8/VAV1/CXCL8/C1QBP/JAM3/MYD88/RHOG/VAV3/MPP1/MDK/PTK2	40
GO:0034113	heterotypic cell-cell adhesion	23/2053	61/18722	4.37191089247816e-08	1.26722054854439e-06	PTPRC/ITGB2/CD44/LILRB2/KLF4/MBP/ITGA5/PERP/TNF/IL1B/DSP/MYADM/ITGA4/IL1RN/ITGAX/BMP7/ITGB1/CD1D/DSG2/DSC2/ITGAV/SIRPA/JAM3	23
GO:0032956	regulation of actin cytoskeleton organization	74/2053	357/18722	4.43034036505008e-08	1.2779827976106e-06	TMSB4X/GMFG/CORO1A/BST2/PLEK/CSF1R/ARHGDIB/NCKAP1L/FLNA/CAPG/PYCARD/WAS/COTL1/HCK/RAC2/GPR65/TMSB10/ABI3/STMN1/MYADM/ARPC3/VASP/PTGER4/MET/PREX1/ARPC5L/DSTN/PTK2B/ICAM1/IQGAP2/ID1/RASA1/RHOBTB3/CCDC88A/KANK1/TACSTD2/S100A10/HRAS/RDX/TRPM2/NRP1/RHOA/ACTR2/NOTCH2/KANK4/RGCC/TWF2/MYO1C/GRB2/JAM3/SCIN/SPTBN1/TJP1/ARPC4/FERMT2/ACTR3/ARPC1A/WASF2/PFN1/RHOG/HCLS1/EPS8/RHOQ/SLC9A1/ECT2/PHPT1/DLG1/RHOB/CD2AP/LIMA1/MDK/TRIOBP/PDGFA/RAC3	74
GO:0038061	NIK/NF-kappaB signaling	39/2053	143/18722	4.78111416320602e-08	1.3725066492287e-06	LAPTM5/TMSB4X/CD14/SPI1/LGALS9/CD86/HAVCR2/TLR2/HMGB1/EGFR/TNF/TLR4/IL1B/APP/RPS3/TLR6/TLR7/NFKBIA/NLRP3/BMP7/LITAF/CALR/TREM2/PHB2/NLRP12/BIRC3/LIMS1/SPHK1/IFI35/RHOA/PRDX1/PHB/RASSF2/REL/RTKN2/TRIP6/IL18/NFAT5/ACTN4	39
GO:0045069	regulation of viral genome replication	28/2053	85/18722	4.80377327230045e-08	1.3725066492287e-06	BST2/IFITM2/APOBEC3A/ISG15/MX1/OAS2/IFITM3/OASL/IFIT1/HACD3/IFI16/TNF/ISG20/PABPC1/TOP2A/PPIA/NOTCH1/RSAD2/OAS1/CXCL8/APOBEC3G/APOBEC3C/DDB1/STAU1/PLSCR1/SRPK1/TOP2B/TRIM28	28
GO:0090322	regulation of superoxide metabolic process	17/2053	36/18722	4.97717187294792e-08	1.41530953733116e-06	TYROBP/ITGB2/CYBA/CLEC7A/TGFB1/EGFR/ITGAM/CD36/GSTP1/HVCN1/SYK/SOD1/BMP7/DHFR/GNAI2/ACP5/GCH1	17
GO:1990266	neutrophil migration	35/2053	122/18722	5.82291616448561e-08	1.64799514089215e-06	FCER1G/S100A8/CCL3L3/ITGB2/CD74/CCL3/CCL4/PECAM1/NCKAP1L/C5AR1/C3AR1/S100A12/RAC2/TREM1/CXCL10/PREX1/SYK/CAMK1D/BSG/JAML/PPIA/LGALS3/DPP4/S100A9/PPIB/ADAM8/VAV1/CXCL8/C1QBP/JAM3/MYD88/RHOG/VAV3/MPP1/MDK	35
GO:0031100	animal organ regeneration	26/2053	76/18722	6.02571509292605e-08	1.69738453321861e-06	LCP1/C5AR1/EGFR/UCP2/PCNA/TYMS/GSTP1/HMOX1/CEBPB/RPS16/CDK1/NOTCH1/HAMP/CCND1/EZH2/SULF2/CCNA2/CDK4/RAP1A/ANXA3/CDKN1A/GLI3/PTPN3/TGFBR3/PPAT/PTPRU	26
GO:0022616	DNA strand elongation	13/2053	22/18722	6.1120792179657e-08	1.71366707045767e-06	PCNA/MCM7/MCM3/NUCKS1/RFC3/MCM4/RFC4/LIG1/POLD3/POLE3/RAD50/POLA1/POLD2	13
GO:0002718	regulation of cytokine production involved in immune response	30/2053	96/18722	6.2279232666817e-08	1.73802509767862e-06	HLA-A/LAPTM5/CD74/BST2/HLA-F/TNFRSF1B/CLEC7A/TGFB1/B2M/HLA-E/LILRB1/LILRB4/SCIMP/TNFRSF14/TNF/IRAK3/TLR4/IL1B/CD36/HMOX1/CCR2/SASH3/BTK/NLRP3/RSAD2/BCL6/GATA3/DDX1/DDX58/IL18	30
GO:0045582	positive regulation of T cell differentiation	29/2053	91/18722	6.36016360741749e-08	1.76671211317153e-06	HLA-DRA/PTPRC/HLA-DRB1/CD74/LGALS9/NCKAP1L/CD86/LILRB2/CD83/LILRB4/RUNX1/SASH3/CD46/SYK/NLRP3/RARA/IL4I1/BCL6/ADAM8/RUNX3/RHOA/SOX4/PNP/GATA3/NFKBIZ/BAD/GLI3/MDK/IL18	29
GO:0032609	interferon-gamma production	33/2053	112/18722	6.83850120871296e-08	1.88215629597604e-06	HLA-A/HLA-DPA1/LAPTM5/HLA-DPB1/HLA-DRB1/CD14/SLC11A1/ISG15/LGALS9/CLEC7A/PYCARD/HAVCR2/LILRB1/LILRB4/HMGB1/TNF/TLR4/HSPD1/IL1B/IRF8/CCR2/SASH3/TLR7/IL27RA/RARA/TLR8/C1QBP/HRAS/ISL1/GATA3/SIRPA/BTN3A1/IL18	33
GO:0032649	regulation of interferon-gamma production	33/2053	112/18722	6.83850120871296e-08	1.88215629597604e-06	HLA-A/HLA-DPA1/LAPTM5/HLA-DPB1/HLA-DRB1/CD14/SLC11A1/ISG15/LGALS9/CLEC7A/PYCARD/HAVCR2/LILRB1/LILRB4/HMGB1/TNF/TLR4/HSPD1/IL1B/IRF8/CCR2/SASH3/TLR7/IL27RA/RARA/TLR8/C1QBP/HRAS/ISL1/GATA3/SIRPA/BTN3A1/IL18	33
GO:0045936	negative regulation of phosphate metabolic process	86/2053	441/18722	6.91537934881855e-08	1.88600113248474e-06	PTPRC/PLEK/TGFB1/NCKAP1L/PYCARD/LYN/SORL1/SLC8A1/FBLN1/CD300A/LILRB4/DUSP1/LRRK2/FBP1/TNF/TNFAIP3/IRAK3/PARP1/IL1B/GSTP1/MYADM/ARRB2/SOCS3/PRKDC/PTPN6/CSK/BMP7/PKIB/PPIA/LGALS3/ENG/SAMSN1/HHEX/GADD45B/NR2F2/NPM1/CDA/SH2B3/LDLRAD4/CTDSPL/DDIT4/CDKN1C/NLRP12/PBK/GNAI2/TRIB1/CHP1/APOC1/CALM2/CIB1/SUZ12/STAT3/PARD3/PRDX3/SIRPA/LRP5/PLPP3/CDKN2A/RASSF2/YWHAE/RGS2/MASTL/PARK7/CORO1C/MVP/PARP14/CDKN1A/DMD/IPO5/IPO7/FKBP1A/PPP1R15A/MIDN/ENSA/VPS25/UBASH3B/PDGFA/MLLT1/PWP1/PKN1/EIF4G1/PPP1R35/PRKAG2/PPARG/URI1/NCAPG2	86
GO:0002399	MHC class II protein complex assembly	11/2053	16/18722	6.94677083798547e-08	1.88600113248474e-06	HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DMB/HLA-DQA1/HLA-DQA2/B2M/HLA-DRB5	11
GO:0002503	peptide antigen assembly with MHC class II protein complex	11/2053	16/18722	6.94677083798547e-08	1.88600113248474e-06	HLA-DPA1/HLA-DPB1/HLA-DRA/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DMB/HLA-DQA1/HLA-DQA2/B2M/HLA-DRB5	11
GO:0031348	negative regulation of defense response	58/2053	258/18722	6.99507767864509e-08	1.89056153476894e-06	HLA-B/HLA-A/PTPRC/HLA-DRB1/FGL2/ISG15/HLA-F/TNFRSF1B/ZFP36/LGALS9/SAMHD1/LYN/HLA-E/HAVCR2/LILRB1/HCK/GPX1/KLF4/FGR/ALOX5/IFI16/AOAH/TNFAIP3/IRAK3/METRNL/SERPINF1/GSTP1/GRN/PTGER4/ARRB2/SOCS3/SYK/NLRP3/TNFAIP8L2/SOD1/SIGLEC10/TREM2/HAMP/OAS1/RHBDF2/NLRP12/PBK/RPS19/NLRC5/C1QBP/STAT2/ISL1/USP15/GATA3/SIRPA/ACP5/PARP14/YES1/MDK/PLK2/MAPK14/SERPING1/PPARG	58
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	32/2053	107/18722	7.31076440351735e-08	1.96702181260556e-06	HLA-B/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/SLC11A1/TNFSF13B/HLA-F/CLEC7A/TGFB1/B2M/HLA-E/CD4/TNF/HSPD1/IL1B/CCR2/SASH3/C3/BTK/STAT6/NLRP3/IL27RA/CD1D/RSAD2/TREM2/MSH2/GATA3/NFKBIZ/RIF1/TFRC/IL18	32
GO:0034504	protein localization to nucleus	63/2053	290/18722	7.4478573400324e-08	1.99496178750868e-06	TXNIP/TGFB1/FLNA/GBP2/LILRB4/RASSF5/JAK2/LRRK2/CDH1/PARP1/CD36/MAGED1/GLUL/NFKBIA/RAN/SYK/HSP90AB1/CDK1/BMP7/NOTCH1/HHEX/PARP9/CALR/RPL23/NPM1/NUP214/PHB2/FERMT1/CHP1/KPNB1/BARD1/TRIM29/STAT3/CSE1L/TXN/TCP1/ARL2/NXT1/CCT6A/TPR/CCT2/YAP1/FERMT2/RANBP17/DTX3L/CHCHD10/SP100/YWHAE/HCLS1/PARK7/ECT2/CDKN1A/IPO5/IPO7/CCT4/CD2AP/GLI3/TFRC/TRIM28/CCT8/LMNA/NUP54/MAPK14	63
GO:0000070	mitotic sister chromatid segregation	43/2053	168/18722	7.49506807596947e-08	1.99868482025853e-06	DUSP1/RAN/PRC1/SMC2/CENPF/ZWINT/SMC3/NUSAP1/MAD2L1/CDC6/ANAPC11/SMC4/UBE2C/CDT1/KPNB1/CENPK/CDCA5/KIF23/FBXO5/RAD21/NUF2/NCAPD3/NCAPH/DSCC1/BUB3/TPR/KIF22/NDC80/EML4/KMT5A/TTK/DSN1/NCAPG/NUDC/AURKB/LCMT1/CHMP4C/KIF4A/CDCA8/BUB1B/KNTC1/NCAPG2/KIFC1	43
GO:0010563	negative regulation of phosphorus metabolic process	86/2053	442/18722	7.68251970415162e-08	2.0396070011022e-06	PTPRC/PLEK/TGFB1/NCKAP1L/PYCARD/LYN/SORL1/SLC8A1/FBLN1/CD300A/LILRB4/DUSP1/LRRK2/FBP1/TNF/TNFAIP3/IRAK3/PARP1/IL1B/GSTP1/MYADM/ARRB2/SOCS3/PRKDC/PTPN6/CSK/BMP7/PKIB/PPIA/LGALS3/ENG/SAMSN1/HHEX/GADD45B/NR2F2/NPM1/CDA/SH2B3/LDLRAD4/CTDSPL/DDIT4/CDKN1C/NLRP12/PBK/GNAI2/TRIB1/CHP1/APOC1/CALM2/CIB1/SUZ12/STAT3/PARD3/PRDX3/SIRPA/LRP5/PLPP3/CDKN2A/RASSF2/YWHAE/RGS2/MASTL/PARK7/CORO1C/MVP/PARP14/CDKN1A/DMD/IPO5/IPO7/FKBP1A/PPP1R15A/MIDN/ENSA/VPS25/UBASH3B/PDGFA/MLLT1/PWP1/PKN1/EIF4G1/PPP1R35/PRKAG2/PPARG/URI1/NCAPG2	86
GO:0032729	positive regulation of interferon-gamma production	25/2053	72/18722	7.71891732469455e-08	2.04024246467697e-06	HLA-A/HLA-DPA1/HLA-DPB1/CD14/SLC11A1/ISG15/LGALS9/CLEC7A/PYCARD/HAVCR2/LILRB1/TNF/TLR4/HSPD1/IL1B/IRF8/CCR2/SASH3/TLR7/IL27RA/TLR8/HRAS/ISL1/BTN3A1/IL18	25
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	46/2053	186/18722	8.15839326655038e-08	2.14694559646063e-06	HLA-DRB1/LGALS1/CD74/BST2/S100A4/TNFSF10/LGALS9/CLEC7A/MTDH/FLNA/TRIM22/S100A12/SECTM1/CD4/CASP1/TNF/TLR4/CD36/HMOX1/WLS/TGM2/TLR6/TMED4/CARD16/LITAF/PRKCB/GJA1/BIRC3/CXXC5/RHOA/APOL3/BRD4/MYD88/SLC20A1/TRIM38/ECT2/DDX1/FKBP1A/TFRC/REL/PLK2/SLC44A2/UBE2N/S100A13/TFG/GAPDH	46
GO:0033260	nuclear DNA replication	17/2053	37/18722	8.26736314781537e-08	2.15670342986488e-06	PCNA/GMNN/MCM3/MCM6/FEN1/BCL6/RAD51/MCM4/CDT1/LIG1/MCM2/BLM/BRCA2/CDC45/DBF4/POLA1/TIPIN	17
GO:0045730	respiratory burst	17/2053	37/18722	8.26736314781537e-08	2.15670342986488e-06	CYBB/CD52/NCF2/SLC11A1/CYBA/NCF1/CLEC7A/HCK/RAC2/PRDX2/GRN/CD24/CAMK1D/TREM2/NCF4/RPS19/INSR	17
GO:0002312	B cell activation involved in immune response	27/2053	82/18722	8.38750908214981e-08	2.17857378757138e-06	PTPRC/LGALS1/SPI1/TGFB1/DOCK10/TLR4/HSPD1/GAPT/IRF8/STAT6/IL27RA/UNG/BCL6/LFNG/PTK2B/GPR183/MFNG/MSH2/CD180/MSH6/NOTCH2/ERCC1/RNF8/RIF1/TFRC/DOCK11/EXO1	27
GO:1900182	positive regulation of protein localization to nucleus	28/2053	87/18722	8.43505478396277e-08	2.18147968550761e-06	TGFB1/FLNA/JAK2/CDH1/PARP1/RAN/HSP90AB1/CDK1/PARP9/NPM1/TCP1/CCT6A/TPR/CCT2/YAP1/FERMT2/DTX3L/HCLS1/PARK7/ECT2/IPO5/CCT4/CD2AP/GLI3/TFRC/TRIM28/CCT8/MAPK14	28
GO:2001233	regulation of apoptotic signaling pathway	73/2053	356/18722	8.61364552057699e-08	2.21810614263785e-06	S100A8/PTPRC/CD74/CD44/TNFSF10/PYCARD/PLAUR/SKIL/GPX1/SOD2/LRRK2/ITGA6/PRDX2/TNF/TNFAIP3/HMGB2/NR4A2/HELLS/PARP1/IL1B/GSTP1/P4HB/G0S2/HMOX1/ARRB2/RPS7/MAGED1/RPS3/CTSH/SOD1/SLC25A5/PPIA/LGALS3/PDIA3/S100A9/IFI6/TIMP3/TREM2/TNFSF12/ICAM1/ERP29/BRCA1/CX3CR1/UBB/GNAI2/PMAIP1/MCL1/ITM2C/NRP1/TRIAP1/SIAH2/BCL2L12/ITGAV/GCLM/TNFRSF12A/YAP1/SP100/SIAH1/FIS1/PARK7/ARHGEF2/HSPA1A/BAD/ING2/ATF3/STK4/TRAP1/RTKN2/LMNA/PEA15/NDUFA13/FIGNL1/URI1	73
GO:2000116	regulation of cysteine-type endopeptidase activity	54/2053	235/18722	9.12877840571294e-08	2.34071241172127e-06	LAPTM5/S100A8/PSMB9/CD44/TNFSF10/LGALS9/CLEC7A/PYCARD/PLAUR/HMGB1/GPX1/KLF4/JAK2/VEGFA/PERP/CASP1/IFI16/TNF/HSPD1/ARRB2/RPS3/CTSH/CTSD/PRDX5/SYK/NLRP3/CARD16/S100A9/IFI6/HSPE1/NR4A1/DHCR24/AIM2/NAIP/BIRC5/NLRP12/ASPH/BIRC3/PMAIP1/RHOA/TRIAP1/SIAH2/NLRP1/RPS6KA1/PRDX3/BCL2L12/PDCD5/CASP8AP2/FIS1/PARK7/BAD/VCP/NDUFA13/PPARG	54
GO:0048771	tissue remodeling	44/2053	175/18722	9.29400842377051e-08	2.37293832096268e-06	TIMP1/CSF1R/TGFB1/FLNA/MEF2C/CST3/RAC2/EGFR/SPP1/SNX10/TNFAIP3/CCR2/RUNX1/TGM2/GPNMB/SYK/CSK/ADAM8/PTK2B/PDK4/HAMP/P2RX7/GJA1/TPP1/EPAS1/SYT7/NOTCH2/VDR/LRP5/LIPA/LGR4/RAB3D/ACP5/RASSF2/INPP5D/TCIRG1/TFRC/FOXC1/MDK/UBASH3B/PTN/CAPN1/IL18/SUCO	44
GO:0051092	positive regulation of NF-kappaB transcription factor activity	40/2053	152/18722	9.3976333058125e-08	2.3892288065625e-06	S100A8/LGALS9/CLEC7A/MTDH/PYCARD/TRIM22/TLR2/S100A12/TNF/IRAK3/TLR4/IL1B/CD36/APP/RPS3/BTK/TLR6/NLRP3/CARD16/PPIA/S100A9/NPM1/ADAM8/AIM2/ICAM1/PRKCB/CX3CR1/SPHK1/CIB1/STAT3/PRDX3/MYD88/TRIM38/ARHGEF2/HSPA1A/TFRC/RTKN2/RPS6KA5/UBE2N/IL18	40
GO:0030593	neutrophil chemotaxis	31/2053	103/18722	9.91038876360732e-08	2.48826712462474e-06	FCER1G/S100A8/CCL3L3/ITGB2/CD74/CCL3/CCL4/NCKAP1L/C5AR1/C3AR1/S100A12/RAC2/TREM1/CXCL10/PREX1/SYK/CAMK1D/BSG/JAML/PPIA/LGALS3/DPP4/S100A9/PPIB/VAV1/CXCL8/C1QBP/JAM3/VAV3/MPP1/MDK	31
GO:0045639	positive regulation of myeloid cell differentiation	31/2053	103/18722	9.91038876360732e-08	2.48826712462474e-06	TYROBP/HLA-DRB1/CD74/EVI2B/ISG15/TGFB1/NCKAP1L/HMGB1/FOS/CD4/CCR1/TNF/HMGB2/STAT1/RUNX1/PRKDC/ZFP36L1/TREM2/TRIB1/FAM210B/NOTCH2/STAT3/SCIN/PITHD1/HCLS1/JUN/INPP5D/HSPA1A/ID2/MAPK14/RCOR1	31
GO:0006310	DNA recombination	65/2053	305/18722	9.91159737975522e-08	2.48826712462474e-06	PTPRC/TGFB1/SAMHD1/WAS/HMGB1/MCM7/HMGB2/HSPD1/PARP1/MCM3/MCM5/PRKDC/RPA3/MCM6/FEN1/FUS/STAT6/TOP2A/IL27RA/NUCKS1/RAD51AP1/UNG/BCL6/RAD51/MCM4/GINS2/RMI2/BRCA1/MSH2/CHEK1/RPA2/MCM2/RAD51C/MSH6/ACTR2/RAD21/BLM/MND1/PSMD14/BRCA2/HMGB3/FANCD2/CDC45/XRCC5/RAD50/PSMC3IP/MAGEF1/RPA1/MMS22L/XRCC6/APEX1/ERCC1/TIMELESS/TOP2B/RNF8/RIF1/TFRC/POLQ/RBBP8/ACTL6A/UBE2N/EXO1/NSMCE4A/FIGNL1/XRCC2	65
GO:0002700	regulation of production of molecular mediator of immune response	42/2053	164/18722	1.04008207869423e-07	2.5894159635541e-06	HLA-A/LAPTM5/PTPRC/CD74/BST2/HLA-F/TNFRSF1B/CLEC7A/TGFB1/CD86/B2M/HLA-E/LILRB1/LILRB4/SCIMP/TNFRSF14/TNF/IRAK3/TLR4/IL1B/CD36/HMOX1/CCR2/SASH3/PRKDC/BTK/STAT6/NLRP3/IL27RA/RSAD2/BCL6/PHB2/MSH2/GATA3/PHB/DDX1/DDX58/RIF1/TFRC/IL18/PKN1/DNAJB9	42
GO:0050792	regulation of viral process	42/2053	164/18722	1.04008207869423e-07	2.5894159635541e-06	HLA-DRB1/LGALS1/CD74/CXCR4/FCN1/BST2/IFITM2/APOBEC3A/ISG15/ZFP36/LGALS9/MX1/OAS2/TRIM22/IFITM3/CD4/OASL/IFIT1/HACD3/IFI16/TNF/P4HB/STAT1/ISG20/PABPC1/TOP2A/CIITA/PPIA/NOTCH1/RSAD2/OAS1/CXCL8/APOBEC3G/APOBEC3C/DDB1/STAU1/PLSCR1/TRIM38/SRPK1/TOP2B/TRIM28/DYNLT1	42
GO:0045185	maintenance of protein location	29/2053	93/18722	1.08371920641301e-07	2.68690712333804e-06	SRGN/TSPO/TMSB4X/FLNA/SORL1/TMSB10/FBN2/CD4/FBN1/NFKBIA/HSPA5/HK2/CCDC88A/GJA1/GPAA1/BARD1/LTBP1/TXN/ARL2/TWF2/ANK3/SCIN/NFKBIE/GOPC/CHCHD10/SP100/VPS13C/PARK7/KDELR2	29
GO:0001906	cell killing	46/2053	188/18722	1.14806179507577e-07	2.83404028236831e-06	HLA-B/TYROBP/HLA-A/LYZ/HLA-DRA/PTPRC/HLA-DRB1/CORO1A/HLA-F/SPI1/LGALS9/CLEC7A/NCKAP1L/B2M/HLA-E/HAVCR2/LILRB1/S100A12/ITGAM/TUBB/TREM1/SLAMF7/STXBP2/ARRB2/C3/CADM1/CTSH/SYK/HSP90AB1/PTPN6/LYST/TUBB4B/CD1D/VAV1/CD59/EMP2/HAMP/P2RX7/ICAM1/HMGN2/CX3CR1/RPS19/MYD88/PRDX1/IL18/GAPDH	46
GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	56/2053	249/18722	1.15250971482978e-07	2.83404028236831e-06	HLA-DRB1/LGALS1/CD74/BST2/S100A4/TNFSF10/LGALS9/CLEC7A/MTDH/FLNA/PYCARD/TRIM22/S100A12/LILRB4/SECTM1/CD4/CASP1/TNF/TNFAIP3/TLR4/IL1B/CD36/GSTP1/STAT1/HMOX1/WLS/TGM2/TLR6/TMED4/CARD16/LITAF/TREM2/PRKCB/GJA1/NLRP12/BIRC3/CXXC5/RHOA/USP10/APOL3/BRD4/MYD88/SLC20A1/TRIM38/ECT2/DDX1/TLE1/FKBP1A/TFRC/REL/PLK2/SLC44A2/UBE2N/S100A13/TFG/GAPDH	56
GO:0043300	regulation of leukocyte degranulation	19/2053	46/18722	1.18249789718164e-07	2.8959132175877e-06	ITGB2/HLA-F/SPI1/LGALS9/NCKAP1L/CD84/LYN/CD300A/RAC2/FGR/ITGAM/PTAFR/HMOX1/STXBP2/CCR2/ADGRE2/PRAM1/SYK/SNX4	19
GO:0031334	positive regulation of protein-containing complex assembly	54/2053	237/18722	1.2281208329436e-07	2.99541666571609e-06	GMFG/CORO1A/MSN/PLEK/ISG15/LCP1/CLEC7A/TGFB1/NCKAP1L/PYCARD/WAS/HCK/GBP5/VEGFA/TNF/TLR4/CD36/ARPC3/VASP/RPS3/MET/TLR6/HSP90AA1/SYK/ARPC5L/LGALS3/PTK2B/ICAM1/IQGAP2/CDT1/CLIP1/FERMT1/RHOA/ACTR2/ARL2/MYO1C/GRB2/MYD88/SCIN/ARPC4/FERMT2/ACTR3/ARPC1A/WASF2/PFN1/PARK7/DLG1/HSPA1A/TFRC/VCP/AKAP9/DRG1/EIF4G1/MPP7	54
GO:0032602	chemokine production	30/2053	99/18722	1.34115897228596e-07	3.25787604603876e-06	AIF1/CD74/CSF1R/LGALS9/CLEC7A/CD84/PYCARD/HAVCR2/TLR2/LILRB4/HMGB1/KLF4/MBP/TNF/TLR4/TREM1/IL1B/GSTP1/APP/HMOX1/TLR7/SYK/TREM2/IL6R/OAS1/SUZ12/SIRPA/MYD88/IL17RA/IL18	30
GO:0002698	negative regulation of immune effector process	32/2053	110/18722	1.49121498574387e-07	3.60777819131581e-06	HLA-B/HLA-A/PTPRC/FGL2/BST2/HLA-F/SPI1/LGALS9/TGFB1/NCKAP1L/CD84/HLA-E/HAVCR2/LILRB1/CD300A/LILRB4/TNF/IRAK3/HMOX1/GRN/CCR2/ARRB2/PRKDC/CD46/PTPN6/LGALS3/IL4I1/BCL6/CD59/CX3CR1/RPS19/SERPING1	32
GO:0042770	signal transduction in response to DNA damage	43/2053	172/18722	1.54025318488841e-07	3.71145345756243e-06	CD74/CD44/PRKDC/PLK3/CLSPN/CDK1/NPM1/CCND1/BRCA1/MSH2/DTL/CHEK1/RPA2/PMAIP1/TRIAP1/EEF1E1/TOPBP1/BLM/USP10/SOX4/FBXO6/SMYD2/WDR76/GTSE1/GRB2/BRCA2/FANCD2/SP100/EIF2AK4/KMT5A/FOXO4/TIPIN/CDKN1A/CDK2/PLK2/PRPF19/FOXM1/E2F1/NDRG1/BRCC3/MAPK14/MDC1/E2F7	43
GO:0007569	cell aging	36/2053	132/18722	1.54883825484874e-07	3.71721181163698e-06	SPI1/B2M/ABI3/NAMPT/PRKDC/VASH1/SOD1/MME/CDK1/BCL6/CALR/NPM1/ICAM1/CHEK1/LIMS1/PAWR/HRAS/EEF1E1/FBXO5/HMGA1/BRCA2/CDK6/CDKN2A/RBL1/ERCC1/CDKN1A/CDK2/ING2/ID2/YPEL3/PLK2/FOXM1/LMNA/TBX3/YBX1/MAPK14	36
GO:0032930	positive regulation of superoxide anion generation	12/2053	20/18722	1.58625808076e-07	3.79185198588048e-06	TYROBP/ITGB2/CYBA/CLEC7A/TGFB1/EGFR/ITGAM/GSTP1/HVCN1/SYK/SOD1/GNAI2	12
GO:1902969	mitotic DNA replication	10/2053	14/18722	1.62543514551551e-07	3.87008367979884e-06	MCM3/MCM6/BCL6/RAD51/MCM4/LIG1/MCM2/BRCA2/CDC45/POLA1	10
GO:0022604	regulation of cell morphogenesis	65/2053	309/18722	1.64352174087489e-07	3.89768001788512e-06	LST1/ITGB2/CXCR4/CORO1A/CCL3/MSN/CD44/CSF1R/FLNA/FMNL1/FBLN1/HCK/FN1/RAC2/PLEKHO1/FGR/VEGFA/PLXNC1/MYH10/MYADM/P4HB/FGD2/GBP1/PRKDC/PREX1/DAG1/CLDN4/SEMA4A/CALR/PTK2B/ICAM1/RASA1/RHOBTB3/KANK1/TACSTD2/S100A10/LIMS1/ALDOA/C1QBP/ITSN2/RDX/NRP1/RHOA/ACTR2/CIB1/FGD3/FERMT2/OBSL1/RHOG/EPS8/RHOQ/EZR/CORO1C/DLG1/FGD4/RHOB/MDK/PTN/HEXB/TRIOBP/PTK2/CFL1/EPB41/ACTN4/RAC3	65
GO:0046034	ATP metabolic process	60/2053	277/18722	1.68307652012424e-07	3.96067546781504e-06	TSPO/TMSB4X/TGFB1/FBP1/PARP1/APP/COX6A1/CDK1/TREM2/HK3/P2RX7/HK2/DDIT4/MSH2/SLC2A6/NDUFA10/HSPA8/UQCRQ/NDUFB9/ALDOA/UQCC2/LDHA/RHOA/NDUFB4/NDUFB7/STAT3/NDUFA6/ARL2/NDUFAB1/DHTKD1/COX7A2/NDUFV1/STOML2/CHCHD10/CHCHD2/FIS1/NUDT5/NDUFS8/NDUFV2/COX6C/PARK7/ATP6V1B1/CYC1/UQCR10/OLA1/UQCRC2/HSPA1A/BAD/NDUFS6/ATP6V1B2/COX5A/INSR/VCP/NDUFC2/NDUFB10/SDHA/GAPDH/PRKAG2/FIGNL1/NDUFA8	60
GO:0000724	double-strand break repair via homologous recombination	37/2053	138/18722	1.68328707382139e-07	3.96067546781504e-06	SAMHD1/WAS/MCM7/PARP1/MCM3/MCM5/RPA3/MCM6/FEN1/FUS/NUCKS1/RAD51AP1/RAD51/MCM4/GINS2/RMI2/BRCA1/CHEK1/RPA2/MCM2/RAD51C/ACTR2/RAD21/BLM/PSMD14/BRCA2/CDC45/MAGEF1/RPA1/MMS22L/TIMELESS/RIF1/POLQ/RBBP8/UBE2N/FIGNL1/XRCC2	37
GO:0071677	positive regulation of mononuclear cell migration	23/2053	65/18722	1.71007989680159e-07	4.00799975812874e-06	AIF1/CCL3/SPI1/CCL4/LGALS9/PYCARD/HMGB1/TNFRSF14/CCR1/TNF/APP/ITGA4/CCR2/CXCL10/LGALS3/CALR/PLA2G7/ADAM8/PTK2B/SPN/CX3CR1/C1QBP/RHOA	23
GO:0051222	positive regulation of protein transport	64/2053	303/18722	1.74604011130694e-07	4.07635823651426e-06	HLA-DRB1/ITGB2/TGFB1/FLNA/SORL1/TLR2/RAC2/EGFR/JAK2/ITGAM/TCAF1/CDH1/OAZ1/TNF/TLR4/IL1B/MYH10/WLS/PLK3/GLUL/RAN/HSP90AB1/CAMK1/MPC2/CDK1/SERP1/PPIA/TREM2/ADAM8/CD33/GJA1/HRAS/CHP1/TRPM2/ISL1/CIB1/FRMD4A/SOX4/ACSL4/PDCD5/MYO1C/ANK3/KIF20B/TMEM30B/TPR/KCNN4/SAE1/FIS1/YWHAE/HCLS1/ECT2/PHPT1/EZR/BAD/NMT1/IPO5/CD2AP/GLI3/TRIM28/B3GAT3/CTDSPL2/HUWE1/TM7SF3/MAPK14	64
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	49/2053	209/18722	1.85317831018329e-07	4.30971700042626e-06	LAPTM5/S100A8/CD44/TNFSF10/LGALS9/CLEC7A/PYCARD/PLAUR/HMGB1/GPX1/KLF4/JAK2/VEGFA/CASP1/TNF/HSPD1/ARRB2/RPS3/CTSH/CTSD/PRDX5/SYK/NLRP3/CARD16/S100A9/IFI6/HSPE1/NR4A1/DHCR24/NAIP/BIRC5/NLRP12/BIRC3/PMAIP1/RHOA/TRIAP1/SIAH2/NLRP1/RPS6KA1/PRDX3/BCL2L12/PDCD5/CASP8AP2/FIS1/PARK7/BAD/VCP/NDUFA13/PPARG	49
GO:0034109	homotypic cell-cell adhesion	28/2053	90/18722	1.88602374692749e-07	4.36916698129921e-06	LGALS1/PLEK/FLNA/LYN/PLAUR/CD9/FERMT3/FN1/ACTB/JAK2/DSP/GNAS/JAK1/SYK/PTPN6/PPIA/SH2B3/DSG2/RDX/DSC2/CLIC1/IL6ST/ANK3/PLPP3/VCL/C1QTNF1/UBASH3B/PTPRU	28
GO:0002688	regulation of leukocyte chemotaxis	34/2053	122/18722	1.93347906527327e-07	4.46187476601524e-06	AIF1/CD74/CCL3/CSF1R/SPI1/CCL4/LGALS9/NCKAP1L/GPSM3/C5AR1/LYN/C3AR1/DUSP1/RAC2/HMGB1/VEGFA/CCR1/CCR2/CXCL10/CAMK1D/DPP4/CALR/PLA2G7/IL6R/PTK2B/CX3CR1/CXCL8/C1QBP/RIN3/JAM3/MPP1/MDK/PTN/PTK2	34
GO:0002706	regulation of lymphocyte mediated immunity	42/2053	168/18722	2.13849096167712e-07	4.91607117626923e-06	HLA-B/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/HLA-F/TNFRSF1B/LGALS9/TGFB1/NCKAP1L/WAS/B2M/HLA-E/HAVCR2/LILRB1/LILRB4/HMGB1/TNF/HSPD1/IL1B/CCR2/ARRB2/SASH3/C3/CADM1/BTK/STAT6/CD46/NLRP3/IL27RA/PTPN6/CD1D/IL4I1/RSAD2/BCL6/TREM2/VAV1/MSH2/GATA3/RIF1/TFRC/IL18	42
GO:0042102	positive regulation of T cell proliferation	30/2053	101/18722	2.18831045887818e-07	5.01139799743095e-06	HLA-A/AIF1/HLA-DPA1/HLA-DPB1/PTPRC/CORO1A/TNFSF13B/HLA-DMB/LGALS9/NCKAP1L/PYCARD/CD86/LILRB2/HLA-E/HAVCR2/HMGB1/IL1B/CCR2/SASH3/RPS3/CD24/CD46/SYK/IL27RA/CD1D/CCDC88B/PNP/IL6ST/TFRC/IL18	30
GO:0042176	regulation of protein catabolic process	77/2053	391/18722	2.20469045445244e-07	5.02971206338959e-06	LAPTM5/TIMP1/MSN/TNFRSF1B/FLNA/SORL1/CST3/GPX1/EGFR/LRRK2/LRP2/CDH1/OAZ1/TNF/TNFAIP3/IRAK3/IL1B/RPS7/PLK3/HSP90AA1/HSP90AB1/RPL5/TIMP2/TIMP3/TREM2/TNFSF12/RPL23/MAD2L1/ADAM8/PTK2B/PSME2/HAMP/PSMC3/GJA1/DTL/UBB/PBK/TRIB1/DDB1/RDX/BARD1/PSMD1/PSMC1/NUDT15/SMARCC1/PSMD14/SDCBP/PSMD2/ATRAID/EFNA1/BAG2/USP14/SVIP/PITHD1/PHB/PSMC2/MAGEF1/TMTC3/UBXN2A/PARK7/EZR/COMMD1/RAD23B/HSPA1A/CDK2/SNRNP70/VCP/PTPN3/PLK2/GABARAP/PTK2/PACSIN3/HUWE1/NDUFA13/MYLIP/GPC3/ALAD	77
GO:0031099	regeneration	47/2053	198/18722	2.21709977392061e-07	5.03886312254685e-06	TSPO/LCP1/FLNA/C5AR1/CD9/GPX1/KLF4/EGFR/UCP2/SPP1/JAK2/PCNA/TYMS/GSTP1/HMOX1/CEBPB/GRN/RUNX1/RPS16/DAG1/CDK1/NREP/NOTCH1/DHFR/HAMP/CCND1/EZH2/SULF2/ISL1/CCNA2/CDK4/FOLR1/JAM3/YAP1/RAP1A/PTPRF/KLF5/ANXA3/CDKN1A/GLI3/MDK/PTPN3/TGFBR3/PTN/MTR/PPAT/PTPRU	47
GO:2001236	regulation of extrinsic apoptotic signaling pathway	39/2053	151/18722	2.30806034488733e-07	5.22579700729207e-06	PTPRC/TNFSF10/PYCARD/SKIL/GPX1/ITGA6/PRDX2/TNF/TNFAIP3/HMGB2/IL1B/GSTP1/G0S2/HMOX1/LGALS3/PDIA3/IFI6/TIMP3/TNFSF12/ICAM1/BRCA1/PMAIP1/MCL1/ITM2C/NRP1/SIAH2/BCL2L12/ITGAV/GCLM/TNFRSF12A/YAP1/SP100/PARK7/ARHGEF2/HSPA1A/ATF3/STK4/LMNA/PEA15	39
GO:0002705	positive regulation of leukocyte mediated immunity	36/2053	134/18722	2.32944192552122e-07	5.25438028313058e-06	HLA-B/TYROBP/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/ITGB2/HLA-F/SPI1/CLEC7A/TGFB1/B2M/HLA-E/SCIMP/ITGAM/TNF/HSPD1/IL1B/PTAFR/SASH3/C3/CADM1/BTK/STAT6/NLRP3/CD1D/RSAD2/TREM2/VAV1/MSH2/GATA3/DDX1/DDX58/RIF1/TFRC/IL18	36
GO:0033157	regulation of intracellular protein transport	52/2053	229/18722	2.34143188390208e-07	5.26164468292603e-06	ITGB2/LCP1/TGFB1/FLNA/SORL1/RAC2/JAK2/LRRK2/ITGAM/TCAF1/CDH1/OAZ1/LMAN1/IL1B/CD36/PLK3/RAN/HSP90AB1/CAMK1/CDK1/IFI27/BNIP3L/FERMT1/HRAS/CHP1/BARD1/CIB1/PTPN14/TXN/PDCD5/MYO1C/ANK3/KIF20B/TMEM30B/TPR/SVIP/SP100/SAE1/FIS1/YWHAE/HCLS1/PARK7/ECT2/NMT1/IPO5/GLI3/TRIM28/B3GAT3/NUP54/CTDSPL2/HUWE1/MAPK14	52
GO:0031570	DNA integrity checkpoint signaling	34/2053	123/18722	2.39363209718379e-07	5.35887782951596e-06	PRKDC/PLK3/CLSPN/CDK1/CDC6/CCND1/BRCA1/NAE1/MSH2/DTL/CHEK1/CDT1/RPA2/TRIAP1/TOPBP1/BLM/SOX4/FBXO6/WDR76/GTSE1/FANCD2/CDC45/EIF2AK4/FOXO4/TIPIN/CDKN1A/TIMELESS/CDK2/PLK2/PRPF19/E2F1/BRCC3/MAPK14/MDC1	34
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	13/2053	24/18722	2.48047883820417e-07	5.51217519600927e-06	TLR2/CD300A/TLR1/IRAK3/TLR4/HSPD1/CD300LF/IRF7/BTK/TLR6/IRF1/TLR8/MYD88	13
GO:0032928	regulation of superoxide anion generation	13/2053	24/18722	2.48047883820417e-07	5.51217519600927e-06	TYROBP/ITGB2/CYBA/CLEC7A/TGFB1/EGFR/ITGAM/GSTP1/HVCN1/SYK/SOD1/GNAI2/ACP5	13
GO:0000725	recombinational repair	37/2053	140/18722	2.50094801016262e-07	5.53715426604269e-06	SAMHD1/WAS/MCM7/PARP1/MCM3/MCM5/RPA3/MCM6/FEN1/FUS/NUCKS1/RAD51AP1/RAD51/MCM4/GINS2/RMI2/BRCA1/CHEK1/RPA2/MCM2/RAD51C/ACTR2/RAD21/BLM/PSMD14/BRCA2/CDC45/MAGEF1/RPA1/MMS22L/TIMELESS/RIF1/POLQ/RBBP8/UBE2N/FIGNL1/XRCC2	37
GO:0006275	regulation of DNA replication	31/2053	107/18722	2.56887279880645e-07	5.66663117383776e-06	EGFR/PCNA/GMNN/NUCKS1/CDK1/S100A11/SMC3/BCL6/CDC6/RFC3/RFC4/RFC2/CCDC88A/ATAD5/CDT1/HRAS/CCNA2/FBXO5/BLM/CACYBP/DSCC1/BRCA2/ID3/ESCO2/DBF4/STOML2/WDR18/JUN/TIPIN/TIMELESS/E2F7	31
GO:0022900	electron transport chain	43/2053	175/18722	2.59075811585083e-07	5.69397388099084e-06	CYBB/NCF2/CYBA/NCF1/ALDH2/SCO2/COX6A1/CDK1/CYB5A/AKR7A2/ADH5/GLDC/NDUFA10/DEGS1/UQCRQ/ASPH/ETFB/NDUFB9/AKR1B1/NDUFB4/NDUFB7/NDUFA6/NDUFAB1/ETFA/COX7A2/NDUFV1/CHCHD2/NDUFS8/NDUFV2/COX6C/PARK7/CYC1/UQCR10/QDPR/NDUFS6/COX5A/PDIA5/UQCRFS1/NDUFC2/NDUFA13/NDUFB10/SDHA/NDUFA8	43
GO:1900024	regulation of substrate adhesion-dependent cell spreading	21/2053	57/18722	2.65958868922924e-07	5.82391683772826e-06	FLNA/FBLN1/MYADM/P4HB/GBP1/PREX1/CALR/KANK1/TACSTD2/S100A10/LIMS1/C1QBP/NRP1/CIB1/FERMT2/CORO1C/MDK/TRIOBP/PTK2/ACTN4/RAC3	21
GO:0061458	reproductive system development	82/2053	427/18722	2.72965129768838e-07	5.9556028313201e-06	TNFSF10/FLNA/CRIP1/NASP/CTSB/PSAP/SPINT1/SPINT2/JUNB/SPP1/RETN/VEGFA/LRP2/PHLDA2/HMGB2/SERPINF1/RRM1/CEBPB/ADGRG1/ARRB2/PRDX4/C3/SOCS3/VASH1/HSP90AB1/BSG/SOD1/PTPN6/MME/RARA/BMP7/NOTCH1/NR2F2/ZFP36L1/DHCR24/HSPA5/ICAM1/CCND1/CTSV/ASPM/RHOBTB3/GJA1/MSH2/UBB/KRT8/ADAMTS1/EPAS1/ASCL2/SF1/NOTCH2/PRDX3/SMARCC1/VDR/GATA3/RPS6/GRB2/BRCA2/LGR4/MGST1/DNAJC19/IDH1/ARID5B/DLG1/ERCC1/PLEKHA5/ING2/GLI3/STK4/FOXC1/TRIM28/PTN/MAP3K4/PTK2/BASP1/TBX3/PLEKHA1/ITGB8/MAPK14/E2F7/FANCA/PPARG/TFAP2C	82
GO:0001909	leukocyte mediated cytotoxicity	34/2053	124/18722	2.95424078229619e-07	6.41801243811656e-06	HLA-B/TYROBP/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/CORO1A/HLA-F/SPI1/LGALS9/NCKAP1L/B2M/HLA-E/HAVCR2/LILRB1/ITGAM/TUBB/TREM1/SLAMF7/STXBP2/ARRB2/CADM1/CTSH/PTPN6/LYST/TUBB4B/CD1D/VAV1/EMP2/ICAM1/CX3CR1/MYD88/PRDX1/IL18	34
GO:0032623	interleukin-2 production	22/2053	62/18722	2.9843757837242e-07	6.41801243811656e-06	LAPTM5/PTPRC/ZFP36/CLEC7A/CD86/HAVCR2/CD83/LILRB4/CD4/TNFAIP3/HOMER3/IL1B/GBP1/CCR2/RUNX1/SASH3/RPS3/PNP/GATA3/SPTBN1/STOML2/EZR	22
GO:0032663	regulation of interleukin-2 production	22/2053	62/18722	2.9843757837242e-07	6.41801243811656e-06	LAPTM5/PTPRC/ZFP36/CLEC7A/CD86/HAVCR2/CD83/LILRB4/CD4/TNFAIP3/HOMER3/IL1B/GBP1/CCR2/RUNX1/SASH3/RPS3/PNP/GATA3/SPTBN1/STOML2/EZR	22
GO:0045428	regulation of nitric oxide biosynthetic process	22/2053	62/18722	2.9843757837242e-07	6.41801243811656e-06	AIF1/TSPO/CLEC7A/KLF4/JAK2/KLF2/TNF/TLR4/IL1B/CD36/TLR6/HSP90AA1/HSP90AB1/PTK2B/ICAM1/DDAH2/CX3CR1/SIRPA/ASS1/KHSRP/ACP5/INSR	22
GO:0009314	response to radiation	86/2053	456/18722	3.16824220296382e-07	6.78909043492247e-06	TIMP1/PTPRC/CYBA/CRIP1/DUSP1/FOS/GPX1/EGFR/SOD2/PCNA/IFI16/ADIRF/PARP1/APP/RRM1/NAMPT/NR2F6/CXCL10/PRKDC/PLK3/FEN1/CARD16/NUCKS1/MME/RAD51AP1/ITGB1/NPM1/RAD51/HSPA5/HAMP/ICAM1/CCND1/BRCA1/MSH2/DTL/PBK/CHEK1/USP1/HRAS/MSH6/DDB1/TRIAP1/TOPBP1/SCARA3/BLM/POLD3/TXN/GATA3/LRP5/BHLHE40/GRB2/BRCA2/FANCD2/XRCC5/YAP1/PNKP/NET1/HMGN1/GNA11/EIF2AK4/XRCC6/JUN/TIPIN/ECT2/BEST1/COPS3/ERCC1/NMT1/CDKN1A/CDS1/RHOB/RNF8/AURKB/ID2/PTN/MAP3K4/BRCC3/TP53I13/MAPK14/UBE4B/TMEM109/FIGNL1/SLC1A3/ALAD/MEIS2/XRCC2	86
GO:0034446	substrate adhesion-dependent cell spreading	31/2053	108/18722	3.22839622758091e-07	6.89337272793077e-06	FLNA/FERMT3/FBLN1/FN1/MYADM/P4HB/GBP1/ITGA4/PARVG/LAMB1/PREX1/LAMA5/CALR/LAMC1/KANK1/TACSTD2/S100A10/LIMS1/C1QBP/NRP1/RHOA/CIB1/ITGAV/EFNA1/FERMT2/CORO1C/MDK/TRIOBP/PTK2/ACTN4/RAC3	31
GO:0006898	receptor-mediated endocytosis	54/2053	244/18722	3.33833941540232e-07	7.07986916088811e-06	FCER1G/ITGB2/CD14/MSR1/SORL1/CD9/ASGR1/B2M/LILRB1/LILRB4/VEGFA/ITGAM/CTSL/LRP2/CXCL16/CD36/ITGA4/ARRB2/C3/LRPAP1/SYK/ITGB1/MARCO/SIGLEC1/BMP2K/PPT1/ARHGAP27/STAB1/CXCL8/AAK1/ITSN2/CAP1/APOC1/RIN3/PDLIM7/AHI1/ITGAV/FOLR1/SDCBP/GRB2/CD63/CLTA/FNBP1L/DGKD/AP1S1/EZR/CD2AP/TFRC/NUMB/INSR/PICALM/AP2M1/AP2A2/LDLRAP1	54
GO:0045429	positive regulation of nitric oxide biosynthetic process	17/2053	40/18722	3.33933828755223e-07	7.07986916088811e-06	AIF1/CLEC7A/KLF4/JAK2/KLF2/TNF/TLR4/IL1B/CD36/TLR6/HSP90AA1/HSP90AB1/PTK2B/ICAM1/DDAH2/ASS1/INSR	17
GO:0048732	gland development	83/2053	436/18722	3.3874882779482e-07	7.15159681716423e-06	TSPO/MSN/CSF1R/TGFB1/MAFB/CRIP1/OAS2/PSAP/GPX1/EGFR/UCP2/JAK2/VEGFA/PCNA/TYMS/CDH1/PRDX2/TNF/TNFAIP3/SERPINF1/HMOX1/WLS/CEBPB/PRKDC/TGM2/MET/KRT18/RPS16/STAT6/DAG1/SOD1/RARA/BMP7/LAMA5/NOTCH1/LMO4/HAMP/CCND1/STAT5A/HK2/SLC29A1/PHB2/EZH2/LSR/HRAS/CDO1/SULF2/NRP1/ISL1/RPS6KA1/UMPS/NOTCH2/HNRNPD/SMARCC1/VDR/GATA3/PBX1/LRP5/ASS1/BRCA2/NCOR2/RAP1A/SEC63/ARID5B/QDPR/TFCP2L1/GLI3/ID2/MTX1/FOXC1/MDK/IGSF3/PTPN3/TGFBR3/NME1/PTN/TBX3/PDGFA/CAPN1/PPAT/ASXL1/COBL/E2F7	83
GO:1901342	regulation of vasculature development	70/2053	348/18722	3.39700848815301e-07	7.15159681716423e-06	CYBB/CXCR4/MTDH/C5AR1/C3AR1/HMGB1/KLF4/VEGFA/ITGA5/KLF2/ALOX5/TNF/TNFAIP3/IL1B/SERPINF1/STAT1/HMOX1/GRN/CCR2/RUNX1/CXCL10/C3/GPNMB/JAK1/CTSH/VASH1/GLUL/ITGAX/ITGB1/ENG/SEMA4A/HHEX/TNFSF12/PTK2B/COL4A2/EMP2/SEMA6A/RRAS/ID1/HK2/BRCA1/PRKCB/FLT1/STAB1/CX3CR1/CXCL8/BTG1/ADAMTS1/AMOT/NRP1/SPHK1/ISL1/STAT3/MYDGF/RGCC/EPN2/EFNA1/TJP1/ANXA3/SP100/FOXO4/AGO2/RHOB/GAB1/FOXC1/MDK/PLK2/PTN/ITGB8/PPARG	70
GO:0051651	maintenance of location in cell	49/2053	213/18722	3.41521858593522e-07	7.16479423622774e-06	S100A8/SRGN/TSPO/TMSB4X/PTPRC/CORO1A/CCL3/CYBA/LYN/SORL1/FTH1/FTL/SLC8A1/TMSB10/CD4/HSP90B1/CXCL10/PTPN6/S100A9/CALR/PTK2B/HSPA5/HK2/ASPM/CCDC88A/GJA1/CAMK2D/GPAA1/TRPM2/BARD1/CALM2/TXN/MCOLN3/ARL2/TWF2/ANK3/SCIN/CHCHD10/SP100/VPS13C/PARK7/ARHGAP21/DMD/GAA/FKBP1A/UBASH3B/AKAP9/GPSM2/KDELR2	49
GO:0071621	granulocyte chemotaxis	34/2053	125/18722	3.63521740415871e-07	7.59619209325703e-06	FCER1G/S100A8/CCL3L3/ITGB2/CD74/CCL3/CSF1R/CCL4/NCKAP1L/C5AR1/C3AR1/S100A12/RAC2/TREM1/ADGRE2/CXCL10/PREX1/SYK/CAMK1D/BSG/JAML/PPIA/LGALS3/DPP4/S100A9/PPIB/VAV1/CXCL8/C1QBP/JAM3/VAV3/MPP1/MDK/PTK2	34
GO:0070372	regulation of ERK1 and ERK2 cascade	64/2053	309/18722	3.65684290394295e-07	7.59619209325703e-06	PTPRC/CCL3L3/HLA-DRB1/CD74/CCL3/CD44/CSF1R/CCL4/LGALS9/TGFB1/PYCARD/C5AR1/LYN/HAVCR2/FBLN1/DUSP1/FN1/SCIMP/HMGB1/KLF4/EGFR/CD4/CCR1/TNF/TLR4/DUSP9/IL1B/CD36/GSTP1/APP/GBP1/ARRB2/GPNMB/GLIPR2/GPBAR1/SYK/PTPN6/CSK/NOTCH1/TIMP3/TREM2/PTK2B/MARCO/GPR183/ICAM1/SEMA6A/RRAS/PHB2/NLRP12/TPBG/GNAI2/HRAS/NRP1/CIB1/NOTCH2/SIRPA/RAP1A/FERMT2/PHB/EZR/DLG1/ATF3/EIF3A/PDGFA	64
GO:0045765	regulation of angiogenesis	69/2053	342/18722	3.65883252491881e-07	7.59619209325703e-06	CYBB/CXCR4/MTDH/C5AR1/C3AR1/HMGB1/KLF4/VEGFA/ITGA5/KLF2/ALOX5/TNF/TNFAIP3/IL1B/SERPINF1/STAT1/HMOX1/GRN/CCR2/RUNX1/CXCL10/C3/GPNMB/JAK1/CTSH/VASH1/GLUL/ITGAX/ITGB1/ENG/SEMA4A/HHEX/TNFSF12/PTK2B/COL4A2/EMP2/SEMA6A/RRAS/HK2/BRCA1/PRKCB/FLT1/STAB1/CX3CR1/CXCL8/BTG1/ADAMTS1/AMOT/NRP1/SPHK1/ISL1/STAT3/MYDGF/RGCC/EPN2/EFNA1/TJP1/ANXA3/SP100/FOXO4/AGO2/RHOB/GAB1/FOXC1/MDK/PLK2/PTN/ITGB8/PPARG	69
GO:0032642	regulation of chemokine production	29/2053	98/18722	3.78476428239498e-07	7.83054679116203e-06	AIF1/CD74/CSF1R/LGALS9/CLEC7A/CD84/PYCARD/HAVCR2/TLR2/LILRB4/HMGB1/KLF4/MBP/TNF/TLR4/IL1B/GSTP1/APP/HMOX1/TLR7/SYK/TREM2/IL6R/OAS1/SUZ12/SIRPA/MYD88/IL17RA/IL18	29
GO:0044839	cell cycle G2/M phase transition	38/2053	148/18722	3.85921860883952e-07	7.92990125104011e-06	APP/PLK3/CLSPN/CDK1/CENPF/NPM1/CDC6/CCND1/BRCA1/WEE1/ATAD5/NAE1/DTL/CHEK1/RAD51C/CALM2/CCNA2/PKMYT1/FBXO5/RAD21/TOPBP1/BLM/ATF5/CDK4/BRD4/PBX1/BACH1/FOXO4/MASTL/CDKN1A/CDK2/ENSA/AURKB/LCMT1/SKP2/CHMP4C/FOXM1/BRCC3	38
GO:1903900	regulation of viral life cycle	38/2053	148/18722	3.85921860883952e-07	7.92990125104011e-06	HLA-DRB1/LGALS1/CD74/FCN1/BST2/IFITM2/APOBEC3A/ISG15/LGALS9/MX1/OAS2/TRIM22/IFITM3/CD4/OASL/IFIT1/HACD3/IFI16/TNF/P4HB/ISG20/PABPC1/TOP2A/CIITA/PPIA/NOTCH1/RSAD2/OAS1/CXCL8/APOBEC3G/APOBEC3C/DDB1/STAU1/PLSCR1/TRIM38/SRPK1/TOP2B/TRIM28	38
GO:0000082	G1/S transition of mitotic cell cycle	49/2053	214/18722	3.96524845261293e-07	8.11996270159644e-06	AIF1/NASP/KLF4/EGFR/PRKDC/PLK3/GPNMB/PTPN6/ITGB1/PSME2/CDC6/CCND1/CCNE1/CTDSPL/WEE1/EZH2/ADAMTS1/RPA2/CCND3/RDX/TRIAP1/CCNE2/SOX4/BRD7/RGCC/CDK4/BRD4/GTSE1/RPS6/CDK6/CDKN2A/DBF4/TFDP1/BACH1/APEX1/RBL1/KMT2E/DLG1/CDKN1A/CDK2AP2/CDK2/ID2/SKP2/RBBP8/PLK2/E2F1/PPAT/EIF4G1/E2F7	49
GO:0008360	regulation of cell shape	39/2053	154/18722	4.00753411546478e-07	8.17864105196894e-06	LST1/ITGB2/CORO1A/CCL3/MSN/CSF1R/FMNL1/HCK/FN1/RAC2/PLEKHO1/FGR/VEGFA/PLXNC1/MYH10/FGD2/DAG1/SEMA4A/PTK2B/ICAM1/RASA1/RHOBTB3/ALDOA/RDX/RHOA/FGD3/FERMT2/RHOG/EPS8/RHOQ/EZR/DLG1/FGD4/RHOB/PTN/HEXB/PTK2/EPB41/RAC3	39
GO:0048608	reproductive structure development	81/2053	424/18722	4.02993638978636e-07	8.19648079278582e-06	TNFSF10/FLNA/CRIP1/NASP/CTSB/PSAP/SPINT1/SPINT2/JUNB/SPP1/RETN/VEGFA/LRP2/PHLDA2/HMGB2/SERPINF1/RRM1/CEBPB/ADGRG1/ARRB2/PRDX4/C3/SOCS3/VASH1/HSP90AB1/BSG/SOD1/PTPN6/MME/RARA/BMP7/NOTCH1/NR2F2/ZFP36L1/DHCR24/HSPA5/ICAM1/CCND1/CTSV/ASPM/RHOBTB3/GJA1/MSH2/UBB/KRT8/ADAMTS1/EPAS1/ASCL2/SF1/NOTCH2/PRDX3/SMARCC1/VDR/GATA3/RPS6/GRB2/BRCA2/LGR4/MGST1/DNAJC19/IDH1/ARID5B/DLG1/ERCC1/ING2/GLI3/STK4/FOXC1/TRIM28/PTN/MAP3K4/PTK2/BASP1/TBX3/PLEKHA1/ITGB8/MAPK14/E2F7/FANCA/PPARG/TFAP2C	81
GO:0031589	cell-substrate adhesion	72/2053	363/18722	4.07154445640609e-07	8.21225850464284e-06	LGALS1/ITGB2/CORO1A/CD44/FLNA/FERMT3/FBLN1/FN1/RAC2/MYO1G/ITGAL/JAK2/VEGFA/ITGA5/ITGA6/CD36/MYADM/P4HB/GBP1/ITGA4/PARVG/LAMB1/PREX1/DAG1/LAMA5/ITGB1/NOTCH1/ITGB4/BCL6/CALR/HPSE/BCAM/PTK2B/EMP2/LAMC1/SIGLEC1/RRAS/ID1/RASA1/KANK1/TACSTD2/S100A10/LIMS1/FERMT1/PLEKHA2/C1QBP/CCDC80/NRP1/RHOA/CIB1/ITGB5/ARL2/ZYX/ITGAV/JAM3/CD63/EFNA1/CDK6/CDKN2A/FERMT2/SLC9A1/VCL/CORO1C/SGCE/STK4/MDK/PTN/TRIOBP/PTK2/TRIP6/ACTN4/RAC3	72
GO:0002761	regulation of myeloid leukocyte differentiation	33/2053	120/18722	4.07875505730595e-07	8.21225850464284e-06	TYROBP/HLA-DRB1/CD74/EVI2B/CCL3/TGFB1/MAFB/LYN/LILRB1/LILRB3/LILRB4/FOS/CD4/FBN1/CCR1/TNF/TLR4/CEBPB/IRF7/RUNX1/RARA/ZFP36L1/TREM2/TRIB1/NOTCH2/CDK6/RASSF2/HCLS1/JUN/INPP5D/ID2/NME1/UBASH3B	33
GO:0051897	positive regulation of protein kinase B signaling	33/2053	120/18722	4.07875505730595e-07	8.21225850464284e-06	CCL3/TGFB1/MTDH/GPX1/EGFR/LRP2/TNF/ARRB2/MET/HSP90AA1/HSP90AB1/ITGB1/ENG/HPSE/ADAM8/PIK3R5/CX3CR1/HBEGF/TPBG/C1QBP/MYDGF/TXN/GATA3/FERMT2/PHB/HCLS1/PARK7/IGF1R/C1QTNF1/INSR/PTK2/PDGFA/IL18	33
GO:0002704	negative regulation of leukocyte mediated immunity	22/2053	63/18722	4.113432493363e-07	8.25437958534382e-06	HLA-B/HLA-A/PTPRC/BST2/HLA-F/SPI1/LGALS9/NCKAP1L/CD84/HLA-E/HAVCR2/LILRB1/CD300A/LILRB4/HMOX1/CCR2/ARRB2/CD46/PTPN6/IL4I1/BCL6/CX3CR1	22
GO:0071675	regulation of mononuclear cell migration	32/2053	115/18722	4.55022667081397e-07	9.10045334162794e-06	AIF1/CCL3/MSN/CSF1R/SPI1/CCL4/LGALS9/PYCARD/C5AR1/LYN/C3AR1/DUSP1/HMGB1/TNFRSF14/CCR1/TNF/APP/ITGA4/CCR2/CXCL10/IL27RA/LGALS3/CALR/PLA2G7/ADAM8/PTK2B/SPN/CX3CR1/C1QBP/RHOA/MDK/PTK2	32
GO:0097305	response to alcohol	55/2053	253/18722	4.80004707227746e-07	9.56820014407468e-06	S100A8/TSPO/CYBB/CD14/CCL3/CYBA/SPI1/TGFB1/RGS19/FOS/KLF4/SOD2/TYMS/GGH/KLF2/CDH1/PARP1/GSTP1/PTGER4/DAG1/NLRP3/SOD1/RARA/TBXAS1/CDK1/ATP2B1/PTK2B/RAD51/HAMP/ICAM1/CCND1/BRCA1/FOSB/KCNMB1/HPGD/CDO1/RHOA/ACTR2/RPL10A/BLM/STAT3/HDAC2/HNRNPD/GATA3/CDK4/PSMD14/PMVK/GNAI1/RPL15/RGS2/EPS8/BAD/CDKN1A/TGFBR3/ALAD	55
GO:0010952	positive regulation of peptidase activity	46/2053	197/18722	4.91995707671e-07	9.77474915902649e-06	LAPTM5/S100A8/TNFSF10/LGALS9/CLEC7A/PYCARD/LYN/FBLN1/FN1/HMGB1/JAK2/MBP/PERP/CASP1/IFI16/TNF/HSPD1/APP/GRN/RPS3/CTSH/CTSD/SYK/NLRP3/CLDN4/S100A9/HSPE1/PSME2/AIM2/NLRP12/ASPH/PCOLCE2/PMAIP1/RHOA/NLRP1/STAT3/PDCD5/PSMD14/EFNA1/CASP8AP2/FIS1/BAD/VCP/PICALM/NDUFA13/PPARG	46
GO:0032735	positive regulation of interleukin-12 production	17/2053	41/18722	5.12300275215765e-07	1.01111896424164e-05	LAPTM5/LGALS9/CLEC7A/TLR2/SCIMP/HMGB1/TLR4/HSPD1/CD36/IRF8/SYK/IRF1/IL16/IRF5/ISL1/MDK/MAPK14	17
GO:1904407	positive regulation of nitric oxide metabolic process	17/2053	41/18722	5.12300275215765e-07	1.01111896424164e-05	AIF1/CLEC7A/KLF4/JAK2/KLF2/TNF/TLR4/IL1B/CD36/TLR6/HSP90AA1/HSP90AB1/PTK2B/ICAM1/DDAH2/ASS1/INSR	17
GO:0002690	positive regulation of leukocyte chemotaxis	28/2053	94/18722	5.14941507768833e-07	1.0129996874141e-05	AIF1/CD74/CCL3/CSF1R/SPI1/CCL4/LGALS9/NCKAP1L/GPSM3/C5AR1/C3AR1/RAC2/HMGB1/VEGFA/CCR1/CCR2/CXCL10/CAMK1D/CALR/PLA2G7/IL6R/PTK2B/CX3CR1/CXCL8/C1QBP/MDK/PTN/PTK2	28
GO:0032102	negative regulation of response to external stimulus	80/2053	420/18722	5.37053144168856e-07	1.05304538072325e-05	HLA-B/HLA-A/AIF1/PTPRC/HLA-DRB1/FGL2/ISG15/HLA-F/TNFRSF1B/ZFP36/LGALS9/SAMHD1/LYN/CD9/HLA-E/HAVCR2/LILRB1/HCK/DUSP1/GPX1/KLF4/FGR/SPP1/ALOX5/PRDX2/IFI16/TNF/AOAH/TNFAIP3/IRAK3/METRNL/SERPINF1/GSTP1/GRN/PTGER4/ARRB2/SOCS3/LILRA2/SYK/NLRP3/TNFAIP8L2/SOD1/CARD16/DPP4/SEMA4A/SIGLEC10/NOTCH1/TREM2/SH2B3/HAMP/SEMA6A/OAS1/RHBDF2/GJA1/NLRP12/PBK/RPS19/NLRC5/C1QBP/TRIB1/NRP1/STAT2/ISL1/USP15/RIN3/GATA3/SIRPA/SEMA6D/ACP5/NENF/PARP14/C1QTNF1/YES1/MDK/PLK2/UBASH3B/PDGFA/MAPK14/SERPING1/PPARG	80
GO:0030888	regulation of B cell proliferation	22/2053	64/18722	5.62267374165132e-07	1.09178130905851e-05	TYROBP/MNDA/PTPRC/CD74/TNFSF13B/NCKAP1L/LYN/MEF2C/CD300A/TLR4/SASH3/BTK/BCL6/GPR183/SLC39A10/PAWR/INPP5D/VAV3/CDKN1A/TFRC/PKN1/CD320	22
GO:0032507	maintenance of protein location in cell	22/2053	64/18722	5.62267374165132e-07	1.09178130905851e-05	SRGN/TSPO/TMSB4X/SORL1/TMSB10/CD4/HSPA5/HK2/CCDC88A/GJA1/GPAA1/BARD1/TXN/ARL2/TWF2/ANK3/SCIN/CHCHD10/SP100/VPS13C/PARK7/KDELR2	22
GO:0080164	regulation of nitric oxide metabolic process	22/2053	64/18722	5.62267374165132e-07	1.09178130905851e-05	AIF1/TSPO/CLEC7A/KLF4/JAK2/KLF2/TNF/TLR4/IL1B/CD36/TLR6/HSP90AA1/HSP90AB1/PTK2B/ICAM1/DDAH2/CX3CR1/SIRPA/ASS1/KHSRP/ACP5/INSR	22
GO:0071353	cellular response to interleukin-4	15/2053	33/18722	5.72262268188957e-07	1.10760439004314e-05	CORO1A/TUBA1B/CD300LF/IL2RG/STAT6/RPLP0/HSP90AB1/HSPA5/MCM2/RPL3/GATA3/CDK4/IMPDH2/PARP14/ALAD	15
GO:0140694	non-membrane-bounded organelle assembly	72/2053	367/18722	6.27921680635456e-07	1.21142446424847e-05	MSN/LCP1/FLNA/HCK/TUBB/TNF/CSRP2/RPS5/RPS23/RPSA/RPS27/RPS3/PRKDC/MEF2A/RPLP0/CENPW/RPS14/RPL5/PRC1/ITGB1/CENPF/SMC3/NPM1/CENPN/BRCA1/ASPM/RPL23A/RPS19/KRT8/C1QBP/RPL3/KPNB1/CENPK/RHOA/LSM4/KIF23/FBXO5/LSM3/TPX2/MRPL20/CENPH/SQLE/CEP152/MYBL2/ANLN/TPR/XRCC5/HAUS8/OBSL1/STAG1/HAUS1/SBDS/EZR/HSPA1A/BRIX1/CDS1/CDK2/AURKB/CENPJ/SASS6/CHMP4C/PLK2/GPSM2/KIF4A/DRG1/CCP110/CCDC69/SAC3D1/MRTO4/KIF11/KNTC1/KIFC1	72
GO:0010639	negative regulation of organelle organization	69/2053	347/18722	6.40832681952101e-07	1.23237054221558e-05	TSPO/TMSB4X/GMFG/CORO1A/CAPG/WAS/LILRB2/DUSP1/TMSB10/GPX1/STMN1/LRRK2/PARP1/MYADM/ARRB2/MET/TOP2A/BMP7/SLC25A5/CENPF/ZWINT/NPM1/MAD2L1/HNRNPA1/BRCA1/KANK1/TACSTD2/CHEK1/CDT1/MCM2/RDX/TRIAP1/CIB1/FBXO5/RAD21/TPX2/KANK4/CKAP2/AURKAIP1/TWF2/BUB3/SCIN/TPR/MID1IP1/SPTBN1/YAP1/TJP1/RAD50/NDC80/WASF2/PFN1/EPS8/TTK/ARHGEF2/ERCC1/HSPA1A/BNIP3/AURKB/LIMA1/LCMT1/TFRC/LMNA/TRIOBP/CCP110/HUWE1/ODF2L/BUB1B/KNTC1/PPARG	69
GO:0042060	wound healing	80/2053	422/18722	6.55082702583824e-07	1.25574958961755e-05	FCER1G/S100A8/TIMP1/SERPINA1/CXCR4/SLC11A1/CD44/PLEK/CLEC7A/TGFB1/FLNA/LYN/PLAUR/WAS/CD9/FERMT3/FBLN1/F5/FN1/HMGB1/GPX1/ACTB/EGFR/JAK2/VEGFA/ITGA5/ALOX5/PRDX2/TNF/TNFAIP3/TLR4/LMAN1/CD36/DSP/HMOX1/GNAS/ELK3/CNN2/SYK/DAG1/CLDN4/PTPN6/JAML/ITGB1/PPIA/HPSE/VAV1/CD59/SH2B3/ENTPD1/GJA1/HBEGF/KANK1/FERMT1/HRAS/ANXA5/CD151/RHOA/CLIC1/SYT7/NOTCH2/IL6ST/TNFRSF12A/PLPP3/PLSCR1/YAP1/FERMT2/DGKD/VCL/VAV3/CDKN1A/C1QTNF1/GLI3/VKORC1/UBASH3B/PTK2/PDGFA/MAPK14/DCBLD2/SERPING1	80
GO:0097193	intrinsic apoptotic signaling pathway	60/2053	288/18722	6.83208942615543e-07	1.30549479480677e-05	S100A8/CD74/BCL2A1/CD44/TNFRSF1B/PYCARD/PLAUR/CRIP1/SKIL/GPX1/SOD2/JAK2/LRRK2/HINT1/PERP/IFI16/TNF/HELLS/PARP1/P4HB/HMOX1/CEBPB/RPS7/RPS3/PRKDC/CD24/SOD1/PPIA/S100A9/IFI6/TREM2/ERP29/BRCA1/DDIT4/MSH2/UBB/PMAIP1/MCL1/HRAS/MSH6/PHLDA3/TRIAP1/BRCA2/SIAH1/FIS1/PARK7/ARHGEF2/HSPA1A/BAD/CDKN1A/BNIP3/PPP1R15A/ING2/TRAP1/RTKN2/E2F1/NDUFA13/TMEM109/FIGNL1/URI1	60
GO:0046822	regulation of nucleocytoplasmic transport	30/2053	106/18722	6.93608538791485e-07	1.32115912150759e-05	TGFB1/FLNA/JAK2/MX2/CDH1/IL1B/CD36/RAN/HSP90AB1/CAMK1/CDK1/NUP214/IFI27/FERMT1/CHP1/BARD1/PTPN14/TXN/TPR/SP100/YWHAE/HCLS1/PARK7/ECT2/IPO5/GLI3/TRIM28/NUP54/CTDSPL2/MAPK14	30
GO:0032392	DNA geometric change	27/2053	90/18722	6.99519071400295e-07	1.32820076848157e-05	HMGB1/MCM7/HMGB2/MCM3/MCM5/MCM6/TOP2A/RAD51/RFC3/MCM4/RFC4/RFC2/MCM2/BLM/HMGA1/DSCC1/CHD9/HMGB3/XRCC5/RAD50/RPA1/XRCC6/HNRNPA2B1/DDX1/POLQ/ASCC3/PURA	27
GO:0002440	production of molecular mediator of immune response	63/2053	308/18722	7.09844306341788e-07	1.3412314392512e-05	HLA-A/HLA-DPA1/LAPTM5/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/HLA-DMA/CD74/BST2/HLA-F/TNFRSF1B/HLA-DQB1/HLA-DMB/CLEC7A/HLA-DQA1/TGFB1/SAMHD1/CD86/HLA-DQA2/B2M/HLA-E/LILRB1/LILRB4/SCIMP/TNFRSF14/HLA-DRB5/TNF/IRAK3/TLR4/TREM1/HSPD1/IL1B/CD36/GAPT/HMOX1/CCR2/SASH3/PRKDC/BTK/STAT6/NLRP3/IL27RA/UNG/RSAD2/BCL6/PHB2/MSH2/MSH6/GATA3/CTNNBL1/PHB/DDX1/ERCC1/DDX58/RNF8/RIF1/TFRC/POLQ/IL18/EXO1/PKN1/DNAJB9	63
GO:0007163	establishment or maintenance of cell polarity	49/2053	218/18722	7.10852662803135e-07	1.3412314392512e-05	MSN/CCL4/NCKAP1L/RAC2/ACTB/SPINT2/DOCK2/PDLIM1/PARVG/HSP90AA1/HSP90AB1/ITGB1/MAD2L1/PTK2B/SPN/WEE1/RHOBTB3/GJA1/KANK1/FAT1/FERMT1/AMOT/CAP1/RHOA/ACTR2/FRMD4A/PARD3/CYTH1/GATA3/DLG5/JAM3/KIF20B/ACTR3/NDC80/RHOG/SLC9A1/PARD6B/DLG1/TCIRG1/RHOB/GPSM2/LMNA/PTK2/AMOTL2/MPP7/AMOTL1/RAC3/MAP7/DYNLT1	49
GO:0046632	alpha-beta T cell differentiation	31/2053	112/18722	7.76914909046187e-07	1.46128196058844e-05	HLA-DRA/HLA-DRB1/LGALS9/NCKAP1L/CD86/CD83/LILRB4/HMGB1/CTSL/PTGER4/RUNX1/SASH3/STAT6/SYK/NLRP3/RARA/SEMA4A/RSAD2/BCL6/IL6R/IRF1/GPR183/SPN/RUNX3/RHOA/STAT3/PNP/GATA3/NFKBIZ/GLI3/IL18	31
GO:0019883	antigen processing and presentation of endogenous antigen	13/2053	26/18722	8.36072195206003e-07	1.56763536601126e-05	HLA-B/HLA-A/HLA-DRA/HLA-DRB1/CD74/HLA-C/HLA-F/B2M/HLA-E/TAP2/TAP1/CD1D/TAPBP	13
GO:0097242	amyloid-beta clearance	16/2053	38/18722	8.63500000190837e-07	1.61401869194549e-05	ITGB2/MSR1/C5AR1/ITGAM/LRP2/TNF/CD36/C3/LRPAP1/MME/TREM2/MARCO/IGF1R/IFNGR1/INSR/PICALM	16
GO:0002483	antigen processing and presentation of endogenous peptide antigen	11/2053	19/18722	8.77502032943847e-07	1.63509695579599e-05	HLA-B/HLA-A/HLA-DRA/HLA-DRB1/HLA-C/HLA-F/B2M/HLA-E/TAP2/TAP1/TAPBP	11
GO:0050921	positive regulation of chemotaxis	36/2053	141/18722	8.94668978034196e-07	1.66192379820594e-05	AIF1/TMSB4X/CD74/CXCR4/CCL3/CSF1R/SPI1/CCL4/LGALS9/TGFB1/NCKAP1L/GPSM3/C5AR1/C3AR1/RAC2/HMGB1/VEGFA/CCR1/CCR2/CXCL10/MET/CAMK1D/CALR/TREM2/PLA2G7/IL6R/PTK2B/IL16/CX3CR1/CXCL8/TPBG/C1QBP/NRP1/MDK/PTN/PTK2	36
GO:0031529	ruffle organization	20/2053	56/18722	9.10035881906933e-07	1.68525163316099e-05	AIF1/PLEK/CSF1R/ABI3/SNX10/ICAM1/KANK1/TACSTD2/HRAS/RDX/SH3YL1/PFN1/RHOG/EPS8/CORO1C/EPS8L2/TCIRG1/LIMA1/PLEKHA1/COBL	20
GO:0001818	negative regulation of cytokine production	70/2053	357/18722	9.13985826626299e-07	1.68735844915624e-05	TYROBP/LAPTM5/SRGN/TSPO/TMSB4X/PTPRC/HLA-DRB1/BST2/SLC11A1/HLA-F/ZFP36/LGALS9/TGFB1/NCKAP1L/CD84/PYCARD/HAVCR2/LILRB1/CD83/LILRB4/FN1/HMGB1/KLF4/KLF2/TNF/TNFAIP3/HOMER3/IRAK3/TLR4/GSTP1/GBP1/HMOX1/CLEC4A/PTGER4/ARRB2/CD24/BTK/GPNMB/TLR6/HSP90AB1/NLRP3/IL27RA/CARD16/PTPN6/RARA/CSK/LILRA5/BCL6/ATP2B1/TREM2/CD33/OAS1/EZH2/CX3CR1/TLR8/NLRP12/C1QBP/SUZ12/RGCC/GATA3/SIRPA/LGR4/ACP5/CHID1/INPP5D/EZR/CD2AP/REL/TIA1/RPS6KA5	70
GO:0045646	regulation of erythrocyte differentiation	18/2053	47/18722	9.71854825569886e-07	1.78868986301206e-05	ISG15/ZFP36/SPI1/NCKAP1L/MAFB/LYN/B2M/HMGB2/STAT1/PRKDC/ZFP36L1/FAM210B/STAT3/CDK6/INPP5D/HSPA1A/HSPA9/MAPK14	18
GO:0046209	nitric oxide metabolic process	25/2053	81/18722	9.95121409639737e-07	1.82591084337566e-05	AIF1/TSPO/CLEC7A/TLR2/KLF4/JAK2/KLF2/TNF/TLR4/IL1B/CD36/TLR6/HSP90AA1/HSP90AB1/PTK2B/ICAM1/DDAH2/CX3CR1/SIRPA/ASS1/KHSRP/ACP5/GCH1/INSR/GCHFR	25
GO:2000573	positive regulation of DNA biosynthetic process	22/2053	66/18722	1.02597390928809e-06	1.87259486157691e-05	KLF4/PCNA/ARRB2/HSP90AA1/HSP90AB1/PKIB/PTK2B/RFC3/HNRNPA1/RFC4/RFC2/RGCC/TCP1/DSCC1/CCT6A/CCT2/XRCC5/PNKP/CCT4/AURKB/CCT8/MAP3K4	22
GO:0006809	nitric oxide biosynthetic process	24/2053	76/18722	1.02680618243134e-06	1.87259486157691e-05	AIF1/TSPO/CLEC7A/KLF4/JAK2/KLF2/TNF/TLR4/IL1B/CD36/TLR6/HSP90AA1/HSP90AB1/PTK2B/ICAM1/DDAH2/CX3CR1/SIRPA/ASS1/KHSRP/ACP5/GCH1/INSR/GCHFR	24
GO:0051402	neuron apoptotic process	53/2053	246/18722	1.03058599048938e-06	1.87379270998069e-05	TYROBP/CORO1A/CCL3/C5AR1/MEF2C/GPX1/SOD2/JAK2/ITGAM/TNF/NR4A2/HSPD1/PARP1/APP/HMOX1/CEBPB/GRN/ARRB2/CTSZ/HSP90AB1/SOD1/TREM2/ADAM8/PTK2B/HSPA5/NAIP/RASA1/PPT1/BTG2/SET/CX3CR1/NAE1/MSH2/MCL1/HRAS/TFAP2A/NRP1/ISL1/RHOA/NLRP1/GATA3/GCLM/MYBL2/SIAH1/FIS1/JUN/PARK7/USP53/BNIP3/MDK/SIGMAR1/GAPDH/XRCC2	53
GO:0032722	positive regulation of chemokine production	23/2053	71/18722	1.03874140450386e-06	1.8829149326354e-05	AIF1/CD74/CSF1R/LGALS9/CLEC7A/CD84/PYCARD/HAVCR2/TLR2/HMGB1/MBP/TNF/TLR4/IL1B/APP/HMOX1/TLR7/SYK/IL6R/OAS1/MYD88/IL17RA/IL18	23
GO:0006091	generation of precursor metabolites and energy	89/2053	490/18722	1.06879613959227e-06	1.93155928841976e-05	CYBB/NCF2/CYBA/NCF1/ALDH2/HMGB1/FBP1/PHLDA2/APP/AGL/SCO2/ACSS1/COX6A1/CDK1/CYB5A/AKR7A2/HK3/P2RX7/ADH5/HK2/ACADVL/DDIT4/GLDC/IDH2/PHB2/MSH2/SLC2A6/NDUFA10/DEGS1/UQCRQ/ASPH/ETFB/NDUFB9/AKR1B1/ALDOA/UQCC2/CISD1/LDHA/RHOA/NDUFB4/NDUFB7/STAT3/NDUFA6/SLC25A4/IL6ST/ARL2/NDUFAB1/FH/DHTKD1/RPIA/ETFA/PDHA1/COX7A2/CYB5R4/NDUFV1/STOML2/MDH1/CHCHD10/CHCHD2/IDH1/NDUFS8/NDUFV2/COX6C/PARK7/CYC1/UQCR10/UQCRC2/UGP2/QDPR/NDUFS6/SUCLG1/GAA/BNIP3/COX5A/INSR/VCP/PHKB/TRAP1/PDIA5/UQCRFS1/GFPT1/NDUFC2/NDUFA13/NDUFB10/SDHA/GAPDH/PRKAG2/COX17/NDUFA8	89
GO:0007051	spindle organization	43/2053	184/18722	1.11914696005684e-06	2.01648100911142e-05	FLNA/STMN1/TUBB/RPS3/RAN/PRC1/SMC3/SPC25/ASPM/KPNB1/RHOA/KIF23/FBXO5/NUF2/TPX2/CENPH/MYBL2/TPR/HAUS8/NDC80/GNAI1/STAG1/TTK/TACC2/HAUS1/SBDS/EZR/DLG1/HSPA1A/NUDC/AURKB/CENPJ/CHMP4C/VCP/NTMT1/PLK2/GPSM2/KIF4A/DRG1/CCDC69/SAC3D1/KIF11/KIFC1	43
GO:0010038	response to metal ion	72/2053	373/18722	1.17911183895301e-06	2.11816498015511e-05	S100A8/TXNIP/TSPO/CYBB/CD14/NCF1/B2M/CRIP1/MEF2C/DUSP1/FOS/EGFR/SOD2/ALOX5AP/JUNB/LRRK2/PCNA/GGH/CDH1/FBP1/AQP9/PARP1/SERPINF1/APP/HMOX1/HVCN1/FUS/MEF2A/BSG/SOD1/MT1X/CDK1/CYB5A/CALR/HSD17B1/C1QA/PTK2B/DTYMK/HSPA5/HAMP/ICAM1/CCND1/FOSB/CAMK2D/KCNMB1/CUTA/TFAP2A/TRPM2/RASGRP2/CALM2/MT2A/SYT7/HNRNPD/CDK4/CACYBP/ASS1/ANK3/PLSCR1/SOD3/JUN/PARK7/ECT2/ERCC1/BAD/QDPR/TCIRG1/BNIP3/PTGES/NDRG1/HOMER1/ALAD/SEC31A	72
GO:0045089	positive regulation of innate immune response	34/2053	131/18722	1.18847791630631e-06	2.12861716353369e-05	TYROBP/MNDA/FCN1/HLA-F/SPI1/CLEC7A/PYCARD/LYN/HLA-E/HAVCR2/HCK/GBP5/HMGB1/IFI16/TLR4/HMGB2/IRF7/CADM1/PRKDC/LILRA2/HSP90AA1/SYK/CD1D/PARP9/ADAM8/VAV1/AIM2/TLR8/RPS19/NLRC5/IFI35/PLSCR1/XRCC5/XRCC6	34
GO:0051091	positive regulation of DNA-binding transcription factor activity	55/2053	260/18722	1.19253773492773e-06	2.1295316695138e-05	S100A8/LGALS9/CLEC7A/MTDH/PYCARD/TRIM22/TLR2/S100A12/JAK2/VEGFA/TNF/IRAK3/TLR4/IL1B/CD36/APP/RPS3/BTK/TLR6/CAMK1D/NLRP3/CARD16/PPIA/S100A9/NPM1/ADAM8/NFAM1/AIM2/ICAM1/PRKCB/PHB2/CX3CR1/SPHK1/CIB1/STAT3/RGCC/PRDX3/LRP5/PLPP3/MYD88/TRIM38/TFDP1/ANXA3/ARID5B/HCLS1/PARK7/ARHGEF2/HSPA1A/DDX58/TFRC/RTKN2/RPS6KA5/UBE2N/IL18/PPARG	55
GO:0042026	protein refolding	12/2053	23/18722	1.24076871896501e-06	2.20585336987779e-05	B2M/HSPD1/HSP90AA1/HSPA5/HSPA8/HSPA6/HSPA14/HSPA1A/FKBP1A/SNRNP70/HSPA9/ST13	12
GO:0000086	G2/M transition of mitotic cell cycle	35/2053	137/18722	1.24263073169782e-06	2.20585336987779e-05	APP/PLK3/CLSPN/CDK1/CENPF/CDC6/CCND1/BRCA1/WEE1/NAE1/DTL/CHEK1/RAD51C/CALM2/CCNA2/PKMYT1/FBXO5/RAD21/TOPBP1/BLM/CDK4/BRD4/PBX1/BACH1/FOXO4/MASTL/CDKN1A/CDK2/ENSA/AURKB/LCMT1/SKP2/CHMP4C/FOXM1/BRCC3	35
GO:0006611	protein export from nucleus	20/2053	57/18722	1.25818561865506e-06	2.22687720115939e-05	TGFB1/IL1B/RAN/CAMK1/CALR/NUP214/IFI27/CHP1/BARD1/PTPN14/CSE1L/TXN/NXT1/TPR/RANBP17/SP100/YWHAE/PARK7/CTDSPL2/HSPA9	20
GO:2001057	reactive nitrogen species metabolic process	25/2053	82/18722	1.28369146373999e-06	2.26533787718821e-05	AIF1/TSPO/CLEC7A/TLR2/KLF4/JAK2/KLF2/TNF/TLR4/IL1B/CD36/TLR6/HSP90AA1/HSP90AB1/PTK2B/ICAM1/DDAH2/CX3CR1/SIRPA/ASS1/KHSRP/ACP5/GCH1/INSR/GCHFR	25
GO:2000249	regulation of actin cytoskeleton reorganization	16/2053	39/18722	1.31544839511043e-06	2.31457195620603e-05	GMFG/CSF1R/ARHGDIB/HCK/ABI3/PTK2B/IQGAP2/HRAS/TRPM2/NRP1/NOTCH2/TJP1/HCLS1/PHPT1/CD2AP/MDK	16
GO:0032757	positive regulation of interleukin-8 production	21/2053	62/18722	1.33525835602302e-06	2.34255851933864e-05	CD14/CD74/FCN1/LGALS9/CLEC7A/PYCARD/TLR2/HMGB1/TLR1/TNF/TLR4/IL1B/LILRA2/TLR7/SYK/TLR8/STAT3/MYD88/PARK7/HSPA1A/DDX58	21
GO:0033627	cell adhesion mediated by integrin	23/2053	72/18722	1.36905429938047e-06	2.39023828167207e-05	ITGB2/NCKAP1L/LYN/FERMT3/ITGA5/FBN1/ITGA4/SYK/PTPN6/ITGB1/DPP4/ITGB4/ICAM1/FERMT1/CIB1/ITGB5/ITGAV/JAM3/PLPP3/EFNA1/PTK2/ITGB8/RAC3	23
GO:0046635	positive regulation of alpha-beta T cell activation	22/2053	67/18722	1.37040328149199e-06	2.39023828167207e-05	HLA-A/HLA-DRA/PTPRC/HLA-DRB1/LGALS9/NCKAP1L/CD86/HLA-E/CD83/LILRB4/CCR2/RUNX1/SASH3/SYK/NLRP3/RARA/RUNX3/RHOA/PNP/NFKBIZ/GLI3/IL18	22
GO:0045839	negative regulation of mitotic nuclear division	18/2053	48/18722	1.39618986020931e-06	2.42815627862488e-05	DUSP1/BMP7/CENPF/ZWINT/MAD2L1/CHEK1/CDT1/FBXO5/RAD21/AURKAIP1/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	18
GO:0098813	nuclear chromosome segregation	58/2053	281/18722	1.4269748307286e-06	2.47452282785306e-05	DUSP1/FEN1/TOP2A/RAN/PRC1/SMC2/CENPF/ZWINT/SMC3/NUSAP1/MAD2L1/CDC6/CCNE1/ANAPC11/RMI2/PHB2/SMC4/UBE2C/CDT1/RAD51C/KPNB1/CENPK/ACTR2/CDCA5/KIF23/FBXO5/RAD21/CCNE2/NUF2/NCAPD3/NCAPH/DSCC1/BUB3/ESCO2/TPR/FANCD2/KIF22/PSMC3IP/ACTR3/NDC80/EML4/KMT5A/STAG1/TTK/DSN1/ECT2/NCAPG/TOP2B/NUDC/AURKB/LCMT1/CHMP4C/KIF4A/CDCA8/BUB1B/KNTC1/NCAPG2/KIFC1	58
GO:0050920	regulation of chemotaxis	49/2053	223/18722	1.43171502247179e-06	2.47558793510972e-05	AIF1/TMSB4X/CD74/CXCR4/CCL3/CSF1R/SPI1/CCL4/LGALS9/TGFB1/NCKAP1L/GPSM3/C5AR1/LYN/C3AR1/DUSP1/RAC2/HMGB1/VEGFA/CCR1/GSTP1/CCR2/CXCL10/MET/CAMK1D/DPP4/SEMA4A/NOTCH1/CALR/TREM2/PLA2G7/IL6R/PTK2B/GPR183/IL16/SEMA6A/CX3CR1/CXCL8/TPBG/C1QBP/NRP1/RIN3/JAM3/SEMA6D/USP14/MPP1/MDK/PTN/PTK2	49
GO:0060333	interferon-gamma-mediated signaling pathway	13/2053	27/18722	1.45039101607645e-06	2.50067416564906e-05	HCK/JAK2/STAT1/JAK1/IFNGR2/HSP90AB1/PARP9/IRF1/NLRC5/SP100/PARP14/IFNGR1/PPARG	13
GO:1902903	regulation of supramolecular fiber organization	73/2053	382/18722	1.46998675266888e-06	2.5271978555912e-05	TMSB4X/GMFG/CORO1A/PLEK/NCKAP1L/FLNA/CAPG/PYCARD/WAS/COTL1/HCK/GPR65/TMSB10/GPX1/STMN1/MYADM/APP/ARPC3/VASP/PTGER4/RPS3/PFDN5/MET/PREX1/ARPC5L/DSTN/TREM2/PTK2B/ICAM1/IQGAP2/ID1/RASA1/CCDC88A/KANK1/TACSTD2/HSPA8/S100A10/CLIP1/RDX/NRP1/RHOA/ACTR2/CIB1/TPX2/KANK4/CKAP2/RGCC/ARL2/TWF2/MYO1C/GRB2/SCIN/MID1IP1/SPTBN1/TJP1/ARPC4/FERMT2/ACTR3/ARPC1A/WASF2/PFN1/HCLS1/EPS8/SLC9A1/PARK7/ARHGEF2/DLG1/HSPA1A/LIMA1/PFDN1/AKAP9/TRIOBP/DRG1	73
GO:0046634	regulation of alpha-beta T cell activation	29/2053	104/18722	1.47815781607111e-06	2.53398482755048e-05	HLA-A/HLA-DRA/PTPRC/HLA-DRB1/LGALS9/NCKAP1L/CD86/HLA-E/LILRB1/CD83/CD300A/LILRB4/HMGB1/TNFRSF14/CCR2/RUNX1/SASH3/SYK/NLRP3/RARA/BCL6/IRF1/RUNX3/RHOA/PNP/GATA3/NFKBIZ/GLI3/IL18	29
GO:0008154	actin polymerization or depolymerization	48/2053	217/18722	1.49500927885231e-06	2.55557141684156e-05	AIF1/TMSB4X/GMFG/CORO1A/PLEK/NCKAP1L/CAPG/PYCARD/WAS/WIPF1/COTL1/HCK/TMSB10/JAK2/MYADM/ARPC3/VASP/PREX1/PSTPIP1/ARPC5L/DIAPH3/DSTN/PTK2B/ICAM1/IQGAP2/RASA1/KANK1/RDX/RHOA/ACTR2/KANK4/TWF2/MYO1C/GRB2/SCIN/SPTBN1/ARPC4/ACTR3/ARPC1A/WASF2/PFN1/HCLS1/EPS8/DLG1/LIMA1/TRIOBP/CFL1/COBL	48
GO:0043409	negative regulation of MAPK cascade	42/2053	180/18722	1.54998743610973e-06	2.6420240388234e-05	PTPRC/LYN/SORL1/FBLN1/CD300A/LILRB4/DUSP1/KLF4/PEBP1/IRAK3/TLR4/DUSP9/IL1B/GSTP1/GBP1/DUSP2/DAG1/PTPN6/CSK/BMP7/PPIA/TIMP3/TREM2/SH2B3/P2RX7/SEMA6A/NLRP12/PBK/MARVELD3/RNF149/SIRPA/EFNA1/PHB/DUSP5/RGS2/EZR/DLG1/IGF1R/ATF3/EIF3A/FOXM1/PPARG	42
GO:0043367	CD4-positive, alpha-beta T cell differentiation	25/2053	83/18722	1.6472824717451e-06	2.79991354970838e-05	HLA-DRA/HLA-DRB1/LGALS9/NCKAP1L/CD86/CD83/HMGB1/CTSL/PTGER4/RUNX1/SASH3/STAT6/NLRP3/RARA/SEMA4A/RSAD2/BCL6/IL6R/GPR183/SPN/RUNX3/STAT3/GATA3/NFKBIZ/IL18	25
GO:0042554	superoxide anion generation	17/2053	44/18722	1.68041260687312e-06	2.84815696080189e-05	TYROBP/ITGB2/CYBB/NCF2/CYBA/NCF1/CLEC7A/TGFB1/EGFR/ITGAM/GSTP1/HVCN1/SYK/SOD1/NCF4/GNAI2/ACP5	17
GO:0032481	positive regulation of type I interferon production	20/2053	58/18722	1.72352929036104e-06	2.91300725131443e-05	CD14/ISG15/OAS2/TLR2/HMGB1/TLR4/HMGB2/HSPD1/STAT1/IRF7/TLR7/HSP90AA1/SYK/IRF1/OAS1/IRF5/TLR8/MYD88/DDX58/GAPDH	20
GO:0030316	osteoclast differentiation	27/2053	94/18722	1.79751782300601e-06	3.02952442079664e-05	TYROBP/CCL3/CSF1R/MAFB/LILRB1/LILRB3/LILRB4/FOS/JUNB/SNX10/FBN1/OSCAR/CCR1/TNF/TLR4/CEBPB/TREM2/GPR183/NOTCH2/RASSF2/INPP5D/TCIRG1/TFRC/UBASH3B/MAPK14/GPC3/GLO1	27
GO:0072331	signal transduction by p53 class mediator	39/2053	163/18722	1.8718174177359e-06	3.14591162644688e-05	CD74/CD44/PYCARD/HINT1/PERP/IFI16/SGK1/RPS7/PLK3/RPL5/RPL37/RPL23/NPM1/DDIT4/MSH2/UBB/CHEK1/PMAIP1/PHLDA3/TRIAP1/EEF1E1/USP10/SOX4/SMYD2/GTSE1/BRCA2/TRIM24/SP100/KMT5A/CDKN1A/ING2/AURKB/RPS20/PLK2/FOXM1/E2F1/NDRG1/TMEM109/E2F7	39
GO:0050868	negative regulation of T cell activation	32/2053	122/18722	1.89159327903776e-06	3.17026806542641e-05	LAPTM5/HLA-DRB1/FGL2/CD74/LGALS9/NCKAP1L/CD86/LILRB2/HAVCR2/LILRB1/CD300A/LILRB4/HMGB1/TNFRSF14/PRDX2/PAG1/CEBPB/RUNX1/GPNMB/TNFAIP8L2/PTPN6/LGALS3/IL4I1/BCL6/IRF1/SPN/RUNX3/PAWR/DLG5/DLG1/GLI3/MDK	32
GO:0045580	regulation of T cell differentiation	36/2053	146/18722	2.17509290690652e-06	3.6352527692031e-05	HLA-DRA/PTPRC/HLA-DRB1/FGL2/CD74/LGALS9/NCKAP1L/CD86/LILRB2/CD83/LILRB4/HMGB1/PRDX2/CCR2/RUNX1/SASH3/CD46/SYK/NLRP3/SOD1/RARA/IL4I1/BCL6/ADAM8/IRF1/RUNX3/RHOA/SOX4/PNP/GATA3/NFKBIZ/BAD/GLI3/MDK/IL18/FANCA	36
GO:0070670	response to interleukin-4	15/2053	36/18722	2.23017682091933e-06	3.71696136819888e-05	CORO1A/TUBA1B/CD300LF/IL2RG/STAT6/RPLP0/HSP90AB1/HSPA5/MCM2/RPL3/GATA3/CDK4/IMPDH2/PARP14/ALAD	15
GO:0002532	production of molecular mediator involved in inflammatory response	27/2053	95/18722	2.25138862755887e-06	3.72130351662623e-05	NCF1/CLEC7A/GPSM3/PYCARD/LYN/LILRB4/GBP5/ALOX5AP/ALOX5/PRDX2/TNF/TLR4/CD36/GRN/BTK/TLR6/SYK/TREM2/EZH2/RPS19/STAT3/SNX4/SIRPA/MYD88/IL17RA/CHID1/MAPK14	27
GO:0032479	regulation of type I interferon production	27/2053	95/18722	2.25138862755887e-06	3.72130351662623e-05	CD14/ISG15/PYCARD/HAVCR2/LILRB1/OAS2/TLR2/HMGB1/TLR4/HMGB2/HSPD1/STAT1/IRF8/IRF7/TLR7/HSP90AA1/SYK/IRF1/OAS1/IRF5/TLR8/SIRPA/MYD88/POLA1/DDX58/REL/GAPDH	27
GO:0032606	type I interferon production	27/2053	95/18722	2.25138862755887e-06	3.72130351662623e-05	CD14/ISG15/PYCARD/HAVCR2/LILRB1/OAS2/TLR2/HMGB1/TLR4/HMGB2/HSPD1/STAT1/IRF8/IRF7/TLR7/HSP90AA1/SYK/IRF1/OAS1/IRF5/TLR8/SIRPA/MYD88/POLA1/DDX58/REL/GAPDH	27
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	13/2053	28/18722	2.43550275348621e-06	4.01456497827397e-05	HLA-B/FCER1G/HLA-A/HLA-C/IFI30/HLA-F/B2M/HLA-E/TAP2/CLEC4A/TAP1/CALR/TAPBP	13
GO:0070664	negative regulation of leukocyte proliferation	26/2053	90/18722	2.46533394536106e-06	4.05260374579901e-05	TYROBP/LST1/MNDA/HLA-DRB1/LGALS9/LYN/CD86/LILRB2/HAVCR2/LILRB1/CD300A/LILRB4/TNFRSF14/TNFAIP3/GSTP1/CEBPB/BTK/GPNMB/PTPN6/IL4I1/SPN/PAWR/DLG5/INPP5D/DLG1/PKN1	26
GO:0043312	neutrophil degranulation	8/2053	11/18722	2.50927753285122e-06	4.1135697259856e-05	ITGB2/SPI1/ITGAM/PTAFR/STXBP2/PRAM1/SYK/ANXA3	8
GO:0030183	B cell differentiation	35/2053	141/18722	2.54214264812123e-06	4.15609152281399e-05	PTPRC/LGALS1/TNFSF13B/SPI1/NCKAP1L/ZFP36L2/KLF6/LYL1/DOCK10/ITGA4/IRF8/PRKDC/BTK/SYK/PTPN6/SLC25A5/ITGB1/IL4I1/HHEX/BCL6/ZFP36L1/LFNG/NFAM1/PTK2B/GPR183/MFNG/EZH2/MSH2/NOTCH2/INPP5D/BAD/TCIRG1/ID2/DOCK11/DNAJB9	35
GO:1902850	microtubule cytoskeleton organization involved in mitosis	36/2053	147/18722	2.58047689363359e-06	4.20729928309825e-05	FLNA/STMN1/RAN/PRC1/ITGB1/SMC3/NUSAP1/MAD2L1/SPC25/GJA1/KPNB1/RHOA/KIF23/NUF2/TPX2/CENPH/MYBL2/TPR/NDC80/GNAI1/STAG1/TTK/TACC2/SBDS/HSPA1A/NUDC/AURKB/CHMP4C/VCP/PLK2/GPSM2/KIF4A/DRG1/KIF11/DYNLT1/KIFC1	36
GO:0032200	telomere organization	38/2053	159/18722	2.59753832893561e-06	4.2236395592449e-05	PCNA/PARP1/PRKDC/RPA3/FEN1/HSP90AA1/HSP90AB1/PKIB/RAD51/CCNE1/HNRNPA1/RPA2/RAD51C/NHP2/RFC1/CCNE2/BLM/HNRNPD/TCP1/CCT6A/BRCA2/CCT2/XRCC5/RAD50/PNKP/GNL3/RPA1/SP100/XRCC6/HNRNPA2B1/APEX1/ERCC1/CCT4/AURKB/RIF1/CCT8/MAP3K4/EXO1	38
GO:0044774	mitotic DNA integrity checkpoint signaling	25/2053	85/18722	2.67185845666389e-06	4.33274344323873e-05	PRKDC/PLK3/CLSPN/CDK1/CDC6/CCND1/BRCA1/NAE1/MSH2/DTL/CHEK1/RPA2/TRIAP1/TOPBP1/BLM/SOX4/GTSE1/FANCD2/FOXO4/TIPIN/CDKN1A/CDK2/PLK2/BRCC3/MDC1	25
GO:0071496	cellular response to external stimulus	63/2053	320/18722	2.74248797103178e-06	4.43529051918886e-05	AIF1/CD68/PTPRC/CYBA/LYN/ASGR1/FOS/EGFR/UCP2/UPP1/LRRK2/CASP1/IFI16/TLR4/NR4A2/IL1B/GSTP1/ITGA4/HMOX1/NAMPT/SLC2A1/PTGER4/CNN2/TLR7/GLUL/DAG1/ENG/ATP2B1/PDK4/COMT/HSPA5/IRF1/ICAM1/CTSV/HNRNPA1/GJA1/TLR8/CHEK1/HSPA8/PMAIP1/MAP3K2/NUDT15/VDR/FOLR1/RALB/MYD88/TRIM24/CASP8AP2/TMEM150C/EIF2AK4/JUN/SLC9A1/BAD/CDKN1A/DCTPP1/BNIP3/ATF3/SKP2/PTN/GABARAP/EIF4G1/WIPI2/PRKAG2	63
GO:0030041	actin filament polymerization	43/2053	190/18722	2.75487102749786e-06	4.44334036693204e-05	AIF1/TMSB4X/GMFG/CORO1A/NCKAP1L/CAPG/PYCARD/WAS/COTL1/HCK/TMSB10/JAK2/MYADM/ARPC3/VASP/PREX1/PSTPIP1/ARPC5L/DIAPH3/PTK2B/ICAM1/IQGAP2/RASA1/KANK1/RDX/RHOA/ACTR2/KANK4/TWF2/MYO1C/GRB2/SCIN/SPTBN1/ARPC4/ACTR3/ARPC1A/WASF2/PFN1/HCLS1/EPS8/DLG1/TRIOBP/COBL	43
GO:0046638	positive regulation of alpha-beta T cell differentiation	18/2053	50/18722	2.7803753646849e-06	4.47245366973443e-05	HLA-DRA/HLA-DRB1/LGALS9/NCKAP1L/CD86/CD83/LILRB4/RUNX1/SASH3/SYK/NLRP3/RARA/RUNX3/RHOA/PNP/NFKBIZ/GLI3/IL18	18
GO:0044843	cell cycle G1/S phase transition	51/2053	241/18722	2.84095290814425e-06	4.55767846226351e-05	AIF1/NASP/KLF4/EGFR/PRKDC/PLK3/GPNMB/PTPN6/ITGB1/PSME2/CDC6/CCND1/CCNE1/CTDSPL/PHB2/WEE1/EZH2/ADAMTS1/RPA2/CCND3/RDX/TRIAP1/CCNA2/CCNE2/SOX4/BRD7/RGCC/CDK4/BRD4/GTSE1/RPS6/CDK6/CDKN2A/DBF4/TFDP1/BACH1/APEX1/RBL1/KMT2E/DLG1/CDKN1A/CDK2AP2/CDK2/ID2/SKP2/RBBP8/PLK2/E2F1/PPAT/EIF4G1/E2F7	51
GO:2000045	regulation of G1/S transition of mitotic cell cycle	35/2053	142/18722	3.02250909818191e-06	4.83601455709106e-05	AIF1/KLF4/EGFR/PRKDC/PLK3/GPNMB/PTPN6/PSME2/CDC6/CCND1/CTDSPL/WEE1/EZH2/ADAMTS1/RPA2/CCND3/RDX/TRIAP1/SOX4/BRD7/RGCC/GTSE1/TFDP1/APEX1/RBL1/KMT2E/DLG1/CDKN1A/CDK2AP2/CDK2/ID2/PLK2/E2F1/EIF4G1/E2F7	35
GO:0090316	positive regulation of intracellular protein transport	38/2053	160/18722	3.05143079361611e-06	4.86930445789805e-05	ITGB2/TGFB1/FLNA/SORL1/RAC2/JAK2/ITGAM/TCAF1/CDH1/OAZ1/IL1B/PLK3/RAN/HSP90AB1/CAMK1/CDK1/HRAS/CHP1/CIB1/PDCD5/MYO1C/ANK3/KIF20B/TMEM30B/TPR/SAE1/FIS1/YWHAE/HCLS1/ECT2/NMT1/IPO5/GLI3/TRIM28/B3GAT3/CTDSPL2/HUWE1/MAPK14	38
GO:0002768	immune response-regulating cell surface receptor signaling pathway	62/2053	315/18722	3.308584042665e-06	5.26565099628382e-05	TYROBP/FCER1G/HLA-A/LAPTM5/HLA-DPB1/MNDA/PTPRC/HLA-DRB1/FCN1/FPR1/HLA-DQB1/CLEC7A/NCKAP1L/C5AR1/LYN/FPR3/LAT2/LILRB2/MEF2C/C3AR1/LILRB1/CD300A/HCK/LILRB4/MYO1G/THEMIS2/FGR/FCGR1B/GBP1/LCP2/PRAM1/RPS3/CD24/LILRA2/BTK/SYK/PTPN6/CSK/LGALS3/VAV1/NFAM1/SLC39A10/CMTM3/PRKCB/PAWR/HRAS/GATA3/PLSCR1/KCNN4/RAP1A/STOML2/NFKBIZ/BCAR1/INPP5D/PHPT1/EZR/VAV3/BTN3A1/YES1/PTK2/UBE2N/PLEKHA1	62
GO:0002832	negative regulation of response to biotic stimulus	29/2053	108/18722	3.40321478386944e-06	5.4019282283642e-05	HLA-B/HLA-A/FGL2/ISG15/HLA-F/LGALS9/SAMHD1/HLA-E/HAVCR2/LILRB1/PRDX2/IFI16/TNFAIP3/IRAK3/GRN/ARRB2/LILRA2/CARD16/IL4I1/OAS1/RPS19/NLRC5/C1QBP/TRIB1/STAT2/USP15/PARP14/SERPING1/PPARG	29
GO:0090068	positive regulation of cell cycle process	50/2053	236/18722	3.41963945486037e-06	5.41251204438627e-05	AIF1/EGFR/IL1B/APP/RANBP1/FEN1/CDK1/RAD51AP1/NUSAP1/NPM1/MAD2L1/CDC6/CCND1/ANAPC11/PHB2/EZH2/ATAD5/DTL/UBE2C/ADAMTS1/CDT1/RAD51C/CCND3/RDX/SPHK1/RHOA/CDCA5/KIF23/FBXO5/RAD21/RGCC/CDK4/BRD4/PBX1/LRP5/PLSCR1/KIF20B/TPR/DBF4/TFDP1/NDC80/APEX1/ECT2/KMT2E/AURKB/CENPJ/INSR/GPSM2/EIF4G1/E2F7	50
GO:0051098	regulation of binding	69/2053	363/18722	3.42792429477797e-06	5.41251204438627e-05	TMSB4X/TGFB1/PLAUR/SORL1/B2M/IFIT2/HMGB1/ACTB/KLF4/JAK2/STMN1/LRRK2/IFIT1/PHLDA2/IFI16/HMGB2/PARP1/APP/ITGA4/HMOX1/GMNN/ARRB2/MET/LRPAP1/CTSZ/NFKBIA/RAN/HSP90AB1/CAMK1/CARD16/NUCKS1/RARA/PARP9/ID1/MFNG/CDT1/S100A10/NRP1/ISL1/CALM2/C4orf3/HDAC2/TXN/GATA3/RALB/BAG2/PTPRF/MSX2/DTX3L/SP100/JUN/PARK7/CDKN1A/FKBP1A/AURKB/STK4/FOXC1/TRIM28/TGFBR3/NME1/PLK2/UBASH3B/AKTIP/MBD2/E2F1/EPB41/EIF4G1/LDLRAP1/PPARG	69
GO:0090329	regulation of DNA-dependent DNA replication	17/2053	46/18722	3.4562182327171e-06	5.44286335860961e-05	PCNA/GMNN/BCL6/RFC3/RFC4/RFC2/CDT1/FBXO5/BLM/DSCC1/BRCA2/DBF4/STOML2/WDR18/TIPIN/TIMELESS/E2F7	17
GO:0002431	Fc receptor mediated stimulatory signaling pathway	14/2053	33/18722	3.76226510178826e-06	5.89388788791894e-05	FCER1G/PTPRC/LYN/HCK/MYO1G/FGR/SYK/CSK/VAV1/PLSCR1/RAP1A/VAV3/YES1/PTK2	14
GO:0010165	response to X-ray	14/2053	33/18722	3.76226510178826e-06	5.89388788791894e-05	NUCKS1/RAD51/HAMP/CCND1/MSH2/BLM/GATA3/BRCA2/XRCC5/XRCC6/ERCC1/CDKN1A/BRCC3/XRCC2	14
GO:0007052	mitotic spindle organization	31/2053	120/18722	3.84476045359006e-06	6.00743820873446e-05	FLNA/STMN1/RAN/PRC1/SMC3/SPC25/KPNB1/RHOA/KIF23/NUF2/TPX2/CENPH/MYBL2/TPR/NDC80/GNAI1/STAG1/TTK/TACC2/SBDS/HSPA1A/NUDC/AURKB/CHMP4C/VCP/PLK2/GPSM2/KIF4A/DRG1/KIF11/KIFC1	31
GO:0098581	detection of external biotic stimulus	12/2053	25/18722	3.86615295218627e-06	6.01292435119651e-05	HLA-B/HLA-A/HLA-DRB1/CLEC7A/LY96/TLR2/TLR1/TLR4/TLR6/CD1D/TREM2/NAIP	12
GO:0034502	protein localization to chromosome	26/2053	92/18722	3.86831466593642e-06	6.01292435119651e-05	SPI1/CDK1/EZH2/TPP1/MSH2/CDT1/RPA2/CDCA5/RAD21/TCP1/CCT6A/BUB3/BRCA2/ESCO2/CCT2/XRCC5/NDC80/GNL3/RPA1/TTK/CCT4/AURKB/VCP/CCT8/BUB1B/KNTC1	26
GO:2000379	positive regulation of reactive oxygen species metabolic process	23/2053	76/18722	3.88394864569662e-06	6.02162580728158e-05	TYROBP/TSPO/ITGB2/CYBA/CLEC7A/TGFB1/EGFR/SOD2/ITGAM/TLR4/CD36/GSTP1/HVCN1/TLR6/SYK/SOD1/PTK2B/GNAI2/DCXR/GRB2/PARK7/CDKN1A/MAPK14	23
GO:0048660	regulation of smooth muscle cell proliferation	41/2053	180/18722	3.9226717959338e-06	6.0659873132997e-05	AIF1/CYBA/TGFB1/MEF2C/KLF4/EGFR/SOD2/JAK2/TNF/TNFAIP3/TLR4/GSTP1/STAT1/PTAFR/HMOX1/NAMPT/PRKDC/TGM2/DNMT1/IL6R/COMT/GJA1/HBEGF/ADAMTS1/GNAI2/HPGD/AKR1B1/TRIB1/RHOA/SF1/MYD88/XRCC5/PHB/XRCC6/JUN/CDKN1A/ID2/SKP2/IL18/LDLRAP1/PPARG	41
GO:0045824	negative regulation of innate immune response	22/2053	71/18722	4.07205789999557e-06	6.28080910025023e-05	HLA-B/HLA-A/ISG15/HLA-F/LGALS9/SAMHD1/HLA-E/HAVCR2/LILRB1/IFI16/TNFAIP3/IRAK3/GRN/ARRB2/OAS1/RPS19/NLRC5/STAT2/USP15/PARP14/SERPING1/PPARG	22
GO:0045071	negative regulation of viral genome replication	19/2053	56/18722	4.10500293507331e-06	6.31538913088201e-05	BST2/IFITM2/APOBEC3A/ISG15/MX1/OAS2/IFITM3/OASL/IFIT1/IFI16/TNF/ISG20/RSAD2/OAS1/APOBEC3G/APOBEC3C/PLSCR1/SRPK1/TRIM28	19
GO:0002456	T cell mediated immunity	29/2053	109/18722	4.15645438193292e-06	6.37819086741625e-05	HLA-B/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/HLA-F/TNFRSF1B/NCKAP1L/WAS/B2M/HLA-E/LILRB1/LILRB4/MYO1G/HMGB1/HSPD1/IL1B/CCR2/SASH3/CTSH/CD46/NLRP3/CD1D/IL4I1/RSAD2/EMP2/ICAM1/GATA3/IL18	29
GO:0014015	positive regulation of gliogenesis	21/2053	66/18722	4.18821523204199e-06	6.39422172830838e-05	TSPO/CXCR4/TNFRSF1B/TGFB1/LYN/TLR2/SPINT1/EGFR/LRP2/TNF/IL1B/DAG1/NOTCH1/RHEB/HDAC2/IL6ST/ID2/MDK/PTN/PRPF19/E2F1	21
GO:0050766	positive regulation of phagocytosis	21/2053	66/18722	4.18821523204199e-06	6.39422172830838e-05	FCER1G/PTPRC/SLC11A1/CYBA/CLEC7A/NCKAP1L/PYCARD/TNF/IL1B/CD36/CD300LF/DOCK2/C3/IL2RG/SIRPB1/CAMK1D/SOD1/CALR/TREM2/SIRPA/RAP1A	21
GO:0007565	female pregnancy	43/2053	193/18722	4.23340518940667e-06	6.44640917118757e-05	TIMP1/ARHGDIB/LGALS9/HAVCR2/FBLN1/CTSB/FOS/UCP2/JUNB/SPP1/VEGFA/IL1B/NAMPT/SLC2A1/SLC38A1/BSG/SOD1/CLDN4/RARA/ITGB4/NR2F2/CALR/EMP2/COMT/CTSV/VMP1/GJA1/FOSB/HPGD/AKR1B1/C1QBP/UMPS/PRDX3/VDR/ACSL4/SLC19A1/MAGED2/RGS2/AGO2/STS/TRIM28/PTN/PPAT	43
GO:0001890	placenta development	35/2053	144/18722	4.24388603769848e-06	6.44640917118757e-05	CTSB/SPINT1/SPINT2/JUNB/SPP1/PHLDA2/CEBPB/SOCS3/VASH1/HSP90AB1/BSG/SOD1/MME/BMP7/NR2F2/ZFP36L1/CTSV/GJA1/KRT8/EPAS1/ASCL2/NOTCH2/PRDX3/VDR/RPS6/GRB2/STK4/TRIM28/PTN/MAP3K4/PTK2/ITGB8/MAPK14/E2F7/PPARG	35
GO:0002429	immune response-activating cell surface receptor signaling pathway	58/2053	291/18722	4.52498898093566e-06	6.83027079742222e-05	TYROBP/FCER1G/HLA-A/LAPTM5/HLA-DPB1/MNDA/PTPRC/HLA-DRB1/FCN1/FPR1/HLA-DQB1/CLEC7A/NCKAP1L/C5AR1/LYN/FPR3/LAT2/MEF2C/C3AR1/CD300A/HCK/LILRB4/MYO1G/THEMIS2/FGR/GBP1/LCP2/PRAM1/RPS3/LILRA2/BTK/SYK/PTPN6/CSK/LGALS3/VAV1/NFAM1/SLC39A10/CMTM3/PRKCB/PAWR/HRAS/GATA3/PLSCR1/KCNN4/RAP1A/STOML2/NFKBIZ/BCAR1/INPP5D/PHPT1/EZR/VAV3/BTN3A1/YES1/PTK2/UBE2N/PLEKHA1	58
GO:0002757	immune response-activating signal transduction	58/2053	291/18722	4.52498898093566e-06	6.83027079742222e-05	TYROBP/FCER1G/HLA-A/LAPTM5/HLA-DPB1/MNDA/PTPRC/HLA-DRB1/FCN1/FPR1/HLA-DQB1/CLEC7A/NCKAP1L/C5AR1/LYN/FPR3/LAT2/MEF2C/C3AR1/CD300A/HCK/LILRB4/MYO1G/THEMIS2/FGR/GBP1/LCP2/PRAM1/RPS3/LILRA2/BTK/SYK/PTPN6/CSK/LGALS3/VAV1/NFAM1/SLC39A10/CMTM3/PRKCB/PAWR/HRAS/GATA3/PLSCR1/KCNN4/RAP1A/STOML2/NFKBIZ/BCAR1/INPP5D/PHPT1/EZR/VAV3/BTN3A1/YES1/PTK2/UBE2N/PLEKHA1	58
GO:0045766	positive regulation of angiogenesis	41/2053	181/18722	4.54213008028578e-06	6.83027079742222e-05	CYBB/CXCR4/MTDH/C5AR1/C3AR1/HMGB1/KLF4/VEGFA/ITGA5/IL1B/HMOX1/GRN/RUNX1/C3/JAK1/CTSH/ITGAX/ITGB1/ENG/TNFSF12/PTK2B/RRAS/HK2/BRCA1/PRKCB/FLT1/CX3CR1/CXCL8/BTG1/NRP1/SPHK1/ISL1/STAT3/MYDGF/TJP1/ANXA3/AGO2/RHOB/GAB1/MDK/ITGB8	41
GO:1904018	positive regulation of vasculature development	41/2053	181/18722	4.54213008028578e-06	6.83027079742222e-05	CYBB/CXCR4/MTDH/C5AR1/C3AR1/HMGB1/KLF4/VEGFA/ITGA5/IL1B/HMOX1/GRN/RUNX1/C3/JAK1/CTSH/ITGAX/ITGB1/ENG/TNFSF12/PTK2B/RRAS/HK2/BRCA1/PRKCB/FLT1/CX3CR1/CXCL8/BTG1/NRP1/SPHK1/ISL1/STAT3/MYDGF/TJP1/ANXA3/AGO2/RHOB/GAB1/MDK/ITGB8	41
GO:0009595	detection of biotic stimulus	15/2053	38/18722	5.0068777286882e-06	7.5103165930323e-05	HLA-B/HLA-A/TSPO/HLA-DRB1/CLEC7A/LY96/TLR2/TLR1/TLR4/TLR6/NLRP3/CD1D/TREM2/NAIP/YAP1	15
GO:0007088	regulation of mitotic nuclear division	29/2053	110/18722	5.05985098211738e-06	7.57084934980157e-05	DUSP1/IL1B/MKI67/BMP7/CENPF/ZWINT/NUSAP1/MAD2L1/ANAPC11/CHEK1/CDT1/SPHK1/PKMYT1/FBXO5/RAD21/RGCC/AURKAIP1/LRP5/BUB3/KIF20B/TPR/NDC80/OBSL1/TTK/AURKB/LCMT1/INSR/BUB1B/KNTC1	29
GO:0044706	multi-multicellular organism process	47/2053	220/18722	5.24197906049758e-06	7.82384934402624e-05	TIMP1/ARHGDIB/LGALS9/HAVCR2/FBLN1/CTSB/FOS/UCP2/JUNB/SPP1/VEGFA/IL1B/PTAFR/NAMPT/SLC2A1/SLC38A1/BSG/SOD1/CLDN4/RARA/ITGB4/NR2F2/CALR/EMP2/COMT/CTSV/VMP1/GJA1/FOSB/HPGD/AKR1B1/C1QBP/SLC6A4/UMPS/PRDX3/VDR/ACSL4/SLC19A1/PITHD1/MAGED2/RGS2/AGO2/STS/TRIM28/PTN/HEXB/PPAT	47
GO:0071479	cellular response to ionizing radiation	22/2053	72/18722	5.26137948426617e-06	7.83331933141365e-05	CYBA/IFI16/NAMPT/NUCKS1/RAD51AP1/RAD51/HSPA5/HAMP/HRAS/BLM/GATA3/GRB2/XRCC5/YAP1/NET1/XRCC6/ECT2/CDKN1A/RHOB/MAPK14/TMEM109/FIGNL1	22
GO:0045787	positive regulation of cell cycle	61/2053	313/18722	5.49737515048037e-06	8.16441854031739e-05	AIF1/EGFR/IL1B/APP/RANBP1/FEN1/RARA/CDK1/CKS1B/RAD51AP1/NUSAP1/CALR/NPM1/MAD2L1/CDC6/CCND1/ANAPC11/PHB2/EZH2/ATAD5/DTL/UBE2C/CHEK1/ADAMTS1/CDT1/RAD51C/CCND3/RDX/SLC6A4/CKS2/SPHK1/RHOA/CDCA5/KIF23/RPS15A/FBXO5/RAD21/RGCC/CDK4/BRD4/PBX1/LRP5/BRCA2/PLSCR1/KIF20B/TPR/DBF4/TFDP1/NDC80/USP22/APEX1/ECT2/KMT2E/AURKB/CENPJ/INSR/GPSM2/TBX3/EIF4G1/E2F7/MEIS2	61
GO:0050672	negative regulation of lymphocyte proliferation	24/2053	83/18722	5.83476440255985e-06	8.64409541119977e-05	TYROBP/LST1/MNDA/HLA-DRB1/LGALS9/LYN/CD86/LILRB2/HAVCR2/LILRB1/CD300A/LILRB4/TNFRSF14/CEBPB/BTK/GPNMB/PTPN6/IL4I1/SPN/PAWR/DLG5/INPP5D/DLG1/PKN1	24
GO:1990830	cellular response to leukemia inhibitory factor	26/2053	94/18722	5.96856140821108e-06	8.82053410080455e-05	KLF4/SNX10/HELLS/SOCS3/NRP2/RPS16/SLC25A5/ICAM1/HK2/PCOLCE2/CACYBP/GCLM/MYBL2/XRCC5/KLF5/SRM/ARID5B/NCL/NFYB/EPS8/UBXN2A/SRSF7/SHMT1/RIF1/TFRC/SMARCA5	26
GO:0002861	regulation of inflammatory response to antigenic stimulus	16/2053	43/18722	6.02946496357117e-06	8.85763531456206e-05	HLA-DRB1/LYN/HLA-E/HCK/GPX1/FGR/TNF/C3/BTK/SYK/TREM2/RHBDF2/PARK7/YES1/PLK2/MAPK14	16
GO:0006268	DNA unwinding involved in DNA replication	9/2053	15/18722	6.08224291599928e-06	8.85763531456206e-05	MCM7/MCM6/RAD51/MCM4/MCM2/BLM/HMGA1/RPA1/PURA	9
GO:0090594	inflammatory response to wounding	9/2053	15/18722	6.08224291599928e-06	8.85763531456206e-05	TIMP1/TGFB1/ALOX5/TLR4/HMOX1/GRN/CCR2/SIGLEC10/MDK	9
GO:0098760	response to interleukin-7	9/2053	15/18722	6.08224291599928e-06	8.85763531456206e-05	LSP1/HMGB1/HSPD1/P4HB/BTK/IL2RG/PDIA3/RAD23B/YBX1	9
GO:0098761	cellular response to interleukin-7	9/2053	15/18722	6.08224291599928e-06	8.85763531456206e-05	LSP1/HMGB1/HSPD1/P4HB/BTK/IL2RG/PDIA3/RAD23B/YBX1	9
GO:0140374	antiviral innate immune response	9/2053	15/18722	6.08224291599928e-06	8.85763531456206e-05	MX1/IFIT1/CXCL10/OAS1/PHB2/NLRP1/PHB/DDX58/AKAP1	9
GO:0001667	ameboidal-type cell migration	84/2053	475/18722	6.27123178693189e-06	9.11074835873882e-05	TIMP1/TMSB4X/ZEB2/ARHGDIB/TGFB1/SLC8A1/MEF2C/FN1/HMGB1/GPX1/KLF4/VEGFA/TNF/SERPINF1/ITGA4/HMOX1/GRN/PDLIM1/MET/GLIPR2/NRP2/CTSH/VASH1/GLUL/BMP7/LAMA5/ITGB1/DPP4/SEMA4A/NOTCH1/ITGB4/NR2F2/CALR/TNFSF12/ARHGAP4/PTK2B/NR4A1/EMP2/FSTL1/STAT5A/SEMA6A/RRAS/ID1/GJA1/HBEGF/KANK1/TACSTD2/TPBG/FERMT1/C1QBP/AMOT/CAP1/NRP1/ISL1/RHOA/CIB1/MARVELD3/RGCC/GATA3/EPHB4/FOLR1/LRP5/PLPP3/ANLN/SEMA6D/EFNA1/RAB25/ANXA3/WASF2/PFN1/SP100/ARID5B/BCAR1/CORO1C/AGO2/RHOB/PLK2/PTN/PTK2/AMOTL2/PKN1/AMOTL1/PPARG/GPC3	84
GO:0002702	positive regulation of production of molecular mediator of immune response	30/2053	117/18722	6.44082189267089e-06	9.33452448213173e-05	HLA-A/LAPTM5/PTPRC/CD74/HLA-F/CLEC7A/TGFB1/CD86/B2M/HLA-E/LILRB1/SCIMP/TNFRSF14/TLR4/IL1B/CD36/SASH3/STAT6/NLRP3/RSAD2/PHB2/MSH2/GATA3/PHB/DDX1/DDX58/RIF1/TFRC/IL18/DNAJB9	30
GO:0001933	negative regulation of protein phosphorylation	65/2053	342/18722	6.5422647655681e-06	9.45869604660449e-05	PTPRC/TGFB1/PYCARD/LYN/SORL1/SLC8A1/FBLN1/CD300A/LILRB4/DUSP1/LRRK2/TNFAIP3/IRAK3/IL1B/GSTP1/MYADM/ARRB2/SOCS3/PRKDC/PTPN6/BMP7/PKIB/PPIA/ENG/SAMSN1/HHEX/GADD45B/NR2F2/NPM1/SH2B3/LDLRAD4/CTDSPL/DDIT4/CDKN1C/NLRP12/PBK/TRIB1/CHP1/CALM2/CIB1/SUZ12/PARD3/SIRPA/LRP5/PLPP3/CDKN2A/RASSF2/RGS2/PARK7/CORO1C/MVP/PARP14/CDKN1A/DMD/IPO5/IPO7/VPS25/UBASH3B/MLLT1/PWP1/PKN1/EIF4G1/PRKAG2/PPARG/NCAPG2	65
GO:0000727	double-strand break repair via break-induced replication	8/2053	12/18722	6.79951594238915e-06	9.73677700580785e-05	MCM7/MCM3/MCM5/MCM6/MCM4/GINS2/MCM2/CDC45	8
GO:0043301	negative regulation of leukocyte degranulation	8/2053	12/18722	6.79951594238915e-06	9.73677700580785e-05	HLA-F/SPI1/LGALS9/NCKAP1L/CD84/CD300A/HMOX1/CCR2	8
GO:1902563	regulation of neutrophil activation	8/2053	12/18722	6.79951594238915e-06	9.73677700580785e-05	ITGB2/SPI1/CD300A/ITGAM/PTAFR/GRN/PRAM1/SYK	8
GO:1904667	negative regulation of ubiquitin protein ligase activity	8/2053	12/18722	6.79951594238915e-06	9.73677700580785e-05	RPS7/RPL5/RPL37/RPL23/MAD2L1/FBXO5/BAG2/RPS20	8
GO:0001894	tissue homeostasis	54/2053	268/18722	6.84372584038213e-06	9.75352851360874e-05	LYZ/CORO1A/CSF1R/PECAM1/B2M/RAC2/ACTB/EGFR/SPP1/MBP/VEGFA/SNX10/TNFAIP3/TLR4/SLC2A1/CCR2/SASH3/CTSH/SYK/SOD1/CSK/ITGB1/NOTCH1/ADAM8/PTK2B/PDK4/LAMC1/HAMP/P2RX7/OAS1/GJA1/TPP1/LSR/AKR1B1/ALDH1A1/EPAS1/BARD1/FH/JAM3/LIPA/RAB3D/PRDX1/YAP1/TJP1/ACP5/INPP5D/VCL/DMD/TCIRG1/TFRC/FOXC1/UBASH3B/HOMER1/RAC3	54
GO:0051348	negative regulation of transferase activity	54/2053	268/18722	6.84372584038213e-06	9.75352851360874e-05	PTPRC/ZFP36/PYCARD/LYN/SORL1/SLC8A1/CD300A/LILRB4/DUSP1/TNFAIP3/IRAK3/IL1B/GSTP1/RPS7/RPL5/PTPN6/CSK/BMP7/PKIB/PPIA/RPL37/HHEX/GADD45B/NR2F2/RPL23/NPM1/MAD2L1/SH2B3/CDKN1C/TRIB1/CHP1/FBXO5/PRDX3/LRP5/BAG2/CDKN2A/DTX3L/RGS2/PARK7/PHPT1/CORO1C/MVP/CDKN1A/IPO5/IPO7/MIDN/VPS25/RPS20/UBASH3B/MLLT1/PKN1/PRKAG2/PPARG/NCAPG2	54
GO:1903038	negative regulation of leukocyte cell-cell adhesion	34/2053	141/18722	6.96298911101245e-06	9.89586478548193e-05	LAPTM5/HLA-DRB1/FGL2/CD74/LGALS9/NCKAP1L/CD86/LILRB2/HAVCR2/LILRB1/CD300A/LILRB4/HMGB1/KLF4/TNFRSF14/PRDX2/PAG1/CEBPB/RUNX1/GPNMB/TNFAIP8L2/PTPN6/LGALS3/IL4I1/BCL6/IRF1/SPN/RUNX3/PAWR/DLG5/ASS1/DLG1/GLI3/MDK	34
GO:0048659	smooth muscle cell proliferation	41/2053	184/18722	6.98508051758608e-06	9.89586478548193e-05	AIF1/CYBA/TGFB1/MEF2C/KLF4/EGFR/SOD2/JAK2/TNF/TNFAIP3/TLR4/GSTP1/STAT1/PTAFR/HMOX1/NAMPT/PRKDC/TGM2/DNMT1/IL6R/COMT/GJA1/HBEGF/ADAMTS1/GNAI2/HPGD/AKR1B1/TRIB1/RHOA/SF1/MYD88/XRCC5/PHB/XRCC6/JUN/CDKN1A/ID2/SKP2/IL18/LDLRAP1/PPARG	41
GO:0009410	response to xenobiotic stimulus	82/2053	462/18722	6.99309876714352e-06	9.89586478548193e-05	TXNIP/TSPO/LGALS1/CYBB/CXCR4/APOBEC3A/CYBA/NCKAP1L/LYN/B2M/SLC8A1/MEF2C/S100A12/FOS/GPX1/EGFR/SOD2/PCNA/TYMS/GGH/CDH1/FBP1/MCM7/ADIRF/HSPD1/IL1B/GSTP1/STAT1/HMOX1/RPN2/HSP90AB1/SOD1/CDK1/TIMP2/CENPF/ENG/CALR/KCNQ1/PTK2B/RAD51/COMT/HSPA5/AIM2/PDE4A/ICAM1/AGPAT2/PLIN2/FOSB/SULT1A1/S100A10/SLC6A4/LDHA/RHOA/UMPS/STAT3/HDAC2/NUDT15/RNF149/PNP/HADH/GATA3/GCLM/ASS1/XRCC5/RAP1A/MGST1/JUN/APEX1/VAV3/UQCRC2/BAD/CDKN1A/QDPR/TFRC/MDK/VKORC1/NME1/PTN/E2F1/PPAT/SLC1A3/ALAD	82
GO:1903707	negative regulation of hemopoiesis	28/2053	106/18722	7.02606399769217e-06	9.89586478548193e-05	FGL2/CD74/CCL3/MAFB/LYN/LILRB1/LILRB3/LILRB4/HMGB1/TMEM176B/FBN1/PRDX2/TLR4/TMEM176A/RUNX1/RARA/BCL6/IRF1/RUNX3/TRIB1/CDK6/INPP5D/GLI3/ID2/MDK/NME1/UBASH3B/HSPA9	28
GO:2000278	regulation of DNA biosynthetic process	28/2053	106/18722	7.02606399769217e-06	9.89586478548193e-05	DUSP1/KLF4/PCNA/ARRB2/HSP90AA1/HSP90AB1/PKIB/PTK2B/RFC3/HNRNPA1/RFC4/RFC2/GJA1/RGCC/HNRNPD/TCP1/DSCC1/CCT6A/CCT2/XRCC5/PNKP/TFDP1/HNRNPA2B1/CDKN1A/CCT4/AURKB/CCT8/MAP3K4	28
GO:0046637	regulation of alpha-beta T cell differentiation	21/2053	68/18722	7.10865472713138e-06	9.98874200533683e-05	HLA-DRA/HLA-DRB1/LGALS9/NCKAP1L/CD86/CD83/LILRB4/HMGB1/RUNX1/SASH3/SYK/NLRP3/RARA/BCL6/RUNX3/RHOA/PNP/GATA3/NFKBIZ/GLI3/IL18	21
GO:0009612	response to mechanical stimulus	46/2053	216/18722	7.1741193082217e-06	0.000100571766003108	TXNIP/CXCR4/CYBA/SLC8A1/FOS/EGFR/RETN/CASP1/TLR4/IL1B/STAT1/SLC2A1/PTGER4/CXCL10/CNN2/TLR7/NFKBIA/DAG1/ENG/KCNQ1/PTK2B/IRF1/BTG2/GJA1/FOSB/TLR8/CHEK1/CNTNAP2/RHOA/MAP3K2/MYD88/CASP8AP2/TMEM150C/JUN/SLC9A1/USP53/BAD/DMD/BNIP3/MDK/PTN/PTK2/MBD2/MAPK14/SLC1A3/MEIS2	46
GO:0032945	negative regulation of mononuclear cell proliferation	24/2053	84/18722	7.32742119468036e-06	0.000102315868749562	TYROBP/LST1/MNDA/HLA-DRB1/LGALS9/LYN/CD86/LILRB2/HAVCR2/LILRB1/CD300A/LILRB4/TNFRSF14/CEBPB/BTK/GPNMB/PTPN6/IL4I1/SPN/PAWR/DLG5/INPP5D/DLG1/PKN1	24
GO:1904589	regulation of protein import	20/2053	63/18722	7.33263726038531e-06	0.000102315868749562	TGFB1/FLNA/JAK2/CDH1/CD36/RAN/HSP90AB1/CDK1/HSPA8/FERMT1/CHP1/PDCD5/TPR/HCLS1/ECT2/IPO5/GLI3/TRIM28/NUP54/MAPK14	20
GO:1990823	response to leukemia inhibitory factor	26/2053	95/18722	7.36923520961623e-06	0.00010258796115475	KLF4/SNX10/HELLS/SOCS3/NRP2/RPS16/SLC25A5/ICAM1/HK2/PCOLCE2/CACYBP/GCLM/MYBL2/XRCC5/KLF5/SRM/ARID5B/NCL/NFYB/EPS8/UBXN2A/SRSF7/SHMT1/RIF1/TFRC/SMARCA5	26
GO:0051258	protein polymerization	58/2053	296/18722	7.8029147537228e-06	0.000108373816023928	AIF1/TMSB4X/GMFG/CORO1A/NCKAP1L/CAPG/PYCARD/WAS/COTL1/HCK/TMSB10/JAK2/STMN1/MYADM/ARPC3/VASP/RPS3/MET/HSP90AA1/PREX1/PSTPIP1/ARPC5L/DIAPH3/PTK2B/ICAM1/IQGAP2/RASA1/KANK1/UBE2C/CLIP1/RDX/RHOA/ACTR2/FBXO5/UBE2S/TPX2/KANK4/ARL2/TWF2/MYO1C/GRB2/SCIN/MID1IP1/SPTBN1/ARPC4/ACTR3/ARPC1A/WASF2/PFN1/HCLS1/EPS8/DLG1/HSPA1A/CENPJ/AKAP9/TRIOBP/DRG1/COBL	58
GO:0007265	Ras protein signal transduction	64/2053	337/18722	7.88312718223991e-06	0.000109235018691546	AIF1/ARHGDIB/WAS/RAC2/GPR65/DOK2/STMN1/LPAR6/HACD3/FBP1/ADGRG1/CYTH4/CTNNAL1/MET/DOK3/DNMT1/TIMP2/ITGB1/NOTCH1/BCL6/ARHGAP4/DENND3/DHCR24/RRAS/RASA1/KANK1/HRAS/RDX/KPNB1/NRP1/RASGRP2/RHOA/CCNA2/NOTCH2/CYTH1/DOK1/SDCBP/RALB/GRB2/RAP1A/CDKN2A/NET1/RIT1/WASF2/RHOG/EPS8/JUN/PARK7/ARHGEF2/CDKN1A/EPS8L2/RHOB/CDK2/TRIM28/PLK2/GPSM2/FOXM1/GABARAP/CFL1/CCDC125/RTKN/ARFGEF3/RALGPS2/DYNLT1	64
GO:0051896	regulation of protein kinase B signaling	41/2053	185/18722	8.03767611145883e-06	0.000111119946241366	CCL3/TGFB1/MTDH/GPX1/KLF4/EGFR/LRP2/TNF/ARRB2/MET/HSP90AA1/HSP90AB1/DAG1/ITGB1/ENG/HPSE/ADAM8/SH2B3/RRAS/PIK3R5/CX3CR1/HBEGF/TPBG/C1QBP/PHLDA3/CIB1/MYDGF/TXN/GATA3/FERMT2/PHB/HCLS1/PARK7/DLG1/IGF1R/C1QTNF1/INSR/PTK2/PDGFA/IL18/PLEKHA1	41
GO:0010950	positive regulation of endopeptidase activity	40/2053	179/18722	8.36060128531826e-06	0.000115318638418183	LAPTM5/S100A8/TNFSF10/LGALS9/CLEC7A/PYCARD/LYN/HMGB1/JAK2/MBP/PERP/CASP1/IFI16/TNF/HSPD1/RPS3/CTSH/CTSD/SYK/NLRP3/S100A9/HSPE1/PSME2/AIM2/NLRP12/ASPH/PMAIP1/RHOA/NLRP1/STAT3/PDCD5/PSMD14/EFNA1/CASP8AP2/FIS1/BAD/VCP/PICALM/NDUFA13/PPARG	40
GO:0031532	actin cytoskeleton reorganization	28/2053	107/18722	8.53199462048695e-06	0.000117412770006701	GMFG/PLEK/CSF1R/ARHGDIB/FLNA/PHACTR1/HCK/GPR65/ABI3/PARVG/PTK2B/IQGAP2/NRK/HRAS/TRPM2/NRP1/RHOA/NOTCH2/GRB2/TJP1/HCLS1/EPS8/BCAR1/PHPT1/EZR/CD2AP/GAB1/MDK	28
GO:0097421	liver regeneration	14/2053	35/18722	8.62111656837908e-06	0.000118367733204289	EGFR/UCP2/PCNA/TYMS/HMOX1/CEBPB/RPS16/HAMP/CCND1/EZH2/SULF2/RAP1A/GLI3/PTPN3	14
GO:0051099	positive regulation of binding	39/2053	173/18722	8.66406750565644e-06	0.000118685856241869	TGFB1/PLAUR/B2M/HMGB1/KLF4/JAK2/STMN1/LRRK2/HMGB2/PARP1/APP/GMNN/MET/RAN/HSP90AB1/RARA/PARP9/MFNG/CDT1/S100A10/NRP1/ISL1/CALM2/TXN/GATA3/RALB/DTX3L/PARK7/FKBP1A/STK4/FOXC1/TRIM28/NME1/PLK2/AKTIP/MBD2/EPB41/EIF4G1/PPARG	39
GO:0110053	regulation of actin filament organization	55/2053	277/18722	8.87835027015148e-06	0.000121344195036239	TMSB4X/GMFG/CORO1A/PLEK/NCKAP1L/FLNA/CAPG/PYCARD/WAS/COTL1/HCK/GPR65/TMSB10/STMN1/MYADM/ARPC3/VASP/PTGER4/MET/PREX1/ARPC5L/DSTN/PTK2B/ICAM1/IQGAP2/ID1/RASA1/CCDC88A/KANK1/TACSTD2/S100A10/RDX/NRP1/RHOA/ACTR2/KANK4/RGCC/TWF2/MYO1C/GRB2/SCIN/SPTBN1/TJP1/ARPC4/FERMT2/ACTR3/ARPC1A/WASF2/PFN1/HCLS1/EPS8/SLC9A1/DLG1/LIMA1/TRIOBP	55
GO:0002888	positive regulation of myeloid leukocyte mediated immunity	10/2053	19/18722	8.92104161910456e-06	0.000121374715906184	TYROBP/ITGB2/SPI1/HLA-E/ITGAM/PTAFR/C3/BTK/DDX1/DDX58	10
GO:0051444	negative regulation of ubiquitin-protein transferase activity	10/2053	19/18722	8.92104161910456e-06	0.000121374715906184	RPS7/RPL5/RPL37/RPL23/MAD2L1/FBXO5/BAG2/DTX3L/PARK7/RPS20	10
GO:0031960	response to corticosteroid	38/2053	167/18722	8.94173218996352e-06	0.000121380979954256	AIF1/CYBB/CYBA/ZFP36/ZFP36L2/DUSP1/HMGB1/FOS/EGFR/PCNA/TYMS/TNF/HSPD1/PARP1/SERPINF1/GSTP1/PTAFR/IL1RN/AGL/ENG/NOTCH1/ZFP36L1/ATP2B1/ICAM1/CCND1/CTSV/DDIT4/FOSB/CDO1/ISL1/RHOA/ASS1/ANXA3/BAD/CDKN1A/MDK/PTPRU/ALAD	38
GO:0002709	regulation of T cell mediated immunity	24/2053	85/18722	9.15911800963761e-06	0.000124051259724211	HLA-B/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/HLA-F/TNFRSF1B/NCKAP1L/WAS/B2M/HLA-E/LILRB1/LILRB4/HMGB1/HSPD1/IL1B/CCR2/SASH3/NLRP3/CD1D/IL4I1/RSAD2/GATA3/IL18	24
GO:0010720	positive regulation of cell development	58/2053	298/18722	9.64762728560839e-06	0.000130373341697411	TYROBP/TSPO/CXCR4/TNFRSF1B/CLEC7A/TGFB1/FLNA/LYN/TLR2/FN1/SPINT1/SKIL/EGFR/VEGFA/PLXNC1/LRP2/TNF/IL1B/SERPINF1/MYADM/P4HB/PRKDC/TGM2/PREX1/DAG1/MME/NOTCH1/CALR/TRPV2/ASPM/CX3CR1/NAP1L1/S100A10/LIMS1/C1QBP/TRIB1/NRP1/ACTR2/CIB1/RHEB/HDAC2/GOLGA4/IL6ST/TWF2/XRCC5/FERMT2/OBSL1/BAD/GLI3/ID2/NUMB/MDK/PTN/PRPF19/TRIOBP/E2F1/RAC3/XRCC2	58
GO:0045471	response to ethanol	33/2053	137/18722	9.67501097743642e-06	0.000130449586212626	S100A8/CYBB/CD14/SPI1/RGS19/SOD2/TYMS/GGH/GSTP1/NLRP3/SOD1/RARA/TBXAS1/CDK1/PTK2B/HAMP/ICAM1/CCND1/KCNMB1/HPGD/CDO1/RHOA/ACTR2/RPL10A/STAT3/HDAC2/GATA3/PSMD14/RPL15/RGS2/EPS8/BAD/ALAD	33
GO:0035710	CD4-positive, alpha-beta T cell activation	27/2053	102/18722	9.75814117913501e-06	0.000130567440361537	HLA-DRA/HLA-DRB1/LGALS9/NCKAP1L/CD86/CD83/HMGB1/CTSL/PTGER4/RUNX1/SASH3/STAT6/NLRP3/RARA/SEMA4A/RSAD2/BCL6/IL6R/GPR183/SPN/RUNX3/STAT3/GATA3/STOML2/NFKBIZ/TCIRG1/IL18	27
GO:1902106	negative regulation of leukocyte differentiation	27/2053	102/18722	9.75814117913501e-06	0.000130567440361537	FGL2/CD74/CCL3/MAFB/LYN/LILRB1/LILRB3/LILRB4/HMGB1/TMEM176B/FBN1/PRDX2/TLR4/TMEM176A/RUNX1/RARA/BCL6/IRF1/RUNX3/TRIB1/CDK6/INPP5D/GLI3/ID2/MDK/NME1/UBASH3B	27
GO:1902749	regulation of cell cycle G2/M phase transition	27/2053	102/18722	9.75814117913501e-06	0.000130567440361537	APP/CLSPN/CDK1/CENPF/NPM1/CDC6/CCND1/BRCA1/ATAD5/NAE1/DTL/CHEK1/RAD51C/FBXO5/RAD21/TOPBP1/BLM/ATF5/CDK4/BRD4/PBX1/FOXO4/CDKN1A/CDK2/AURKB/CHMP4C/BRCC3	27
GO:1900027	regulation of ruffle assembly	13/2053	31/18722	9.77079678705505e-06	0.000130567440361537	ABI3/ICAM1/KANK1/TACSTD2/HRAS/RDX/SH3YL1/PFN1/RHOG/EPS8/CORO1C/EPS8L2/COBL	13
GO:0043523	regulation of neuron apoptotic process	45/2053	212/18722	9.81390173762206e-06	0.000130852023168294	TYROBP/CORO1A/CCL3/C5AR1/MEF2C/SOD2/JAK2/ITGAM/TNF/NR4A2/HSPD1/PARP1/HMOX1/CEBPB/GRN/ARRB2/CTSZ/HSP90AB1/SOD1/TREM2/ADAM8/PTK2B/NAIP/RASA1/PPT1/BTG2/SET/CX3CR1/NAE1/MSH2/MCL1/HRAS/TFAP2A/NRP1/ISL1/RHOA/GATA3/GCLM/MYBL2/FIS1/JUN/PARK7/MDK/SIGMAR1/XRCC2	45
GO:0051383	kinetochore organization	11/2053	23/18722	1.03313107837881e-05	0.000137141293590108	CENPW/SMC2/CENPF/CENPN/SMC4/CDT1/CENPK/NUF2/CENPH/NDC80/KNTC1	11
GO:1903306	negative regulation of regulated secretory pathway	11/2053	23/18722	1.03313107837881e-05	0.000137141293590108	HLA-F/SPI1/LGALS9/NCKAP1L/CD84/CD300A/HMOX1/CCR2/NOTCH1/GNAI2/RAP1A	11
GO:2001020	regulation of response to DNA damage stimulus	46/2053	219/18722	1.04889590430999e-05	0.000138926609842383	CD74/CD44/WAS/HMGB1/SKIL/EGFR/IER3/PCNA/PARP1/DEK/RPS3/PRKDC/FUS/RAD51AP1/PARP9/NPM1/RAD51/RMI2/BRCA1/CHEK1/RPA2/PMAIP1/USP1/MCL1/ACTR2/TRIAP1/EEF1E1/FBXO5/SMYD2/WDR76/PNKP/DTX3L/MAGEF1/KMT5A/ERCC1/TIMELESS/RNF8/ING2/RIF1/POLQ/TRIM28/FOXM1/UBE2N/BRCC3/NSMCE4A/FIGNL1	46
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	15/2053	40/18722	1.05205588358705e-05	0.000139038222500492	DUSP1/CENPF/ZWINT/MAD2L1/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	15
GO:0008064	regulation of actin polymerization or depolymerization	41/2053	187/18722	1.05945259025276e-05	0.000139401656612205	TMSB4X/GMFG/CORO1A/PLEK/NCKAP1L/CAPG/PYCARD/WAS/COTL1/HCK/TMSB10/MYADM/ARPC3/VASP/PREX1/ARPC5L/DSTN/PTK2B/ICAM1/IQGAP2/RASA1/KANK1/RDX/RHOA/ACTR2/KANK4/TWF2/MYO1C/GRB2/SCIN/SPTBN1/ARPC4/ACTR3/ARPC1A/WASF2/PFN1/HCLS1/EPS8/DLG1/LIMA1/TRIOBP	41
GO:0033044	regulation of chromosome organization	41/2053	187/18722	1.05945259025276e-05	0.000139401656612205	DUSP1/PARP1/FEN1/TOP2A/DNMT1/PKIB/CENPF/ZWINT/MAD2L1/CDC6/ANAPC11/RMI2/HNRNPA1/UBE2C/CDT1/MCM2/CDCA5/FBXO5/RAD21/HNRNPD/TCP1/CCT6A/BUB3/TPR/CCT2/XRCC5/RAD50/PNKP/NDC80/GNL3/HNRNPA2B1/TTK/ERCC1/CCT4/AURKB/LCMT1/TRIM28/CCT8/MAP3K4/BUB1B/KNTC1	41
GO:0030832	regulation of actin filament length	41/2053	188/18722	1.21363936725088e-05	0.000159339960689393	TMSB4X/GMFG/CORO1A/PLEK/NCKAP1L/CAPG/PYCARD/WAS/COTL1/HCK/TMSB10/MYADM/ARPC3/VASP/PREX1/ARPC5L/DSTN/PTK2B/ICAM1/IQGAP2/RASA1/KANK1/RDX/RHOA/ACTR2/KANK4/TWF2/MYO1C/GRB2/SCIN/SPTBN1/ARPC4/ACTR3/ARPC1A/WASF2/PFN1/HCLS1/EPS8/DLG1/LIMA1/TRIOBP	41
GO:0002720	positive regulation of cytokine production involved in immune response	20/2053	65/18722	1.24157271545529e-05	0.00016229708698762	HLA-A/LAPTM5/CD74/HLA-F/CLEC7A/B2M/HLA-E/LILRB1/SCIMP/TNFRSF14/TLR4/IL1B/CD36/SASH3/NLRP3/RSAD2/GATA3/DDX1/DDX58/IL18	20
GO:0045453	bone resorption	20/2053	65/18722	1.24157271545529e-05	0.00016229708698762	CSF1R/RAC2/EGFR/SPP1/SNX10/TNFAIP3/SYK/CSK/ADAM8/PTK2B/PDK4/HAMP/P2RX7/TPP1/RAB3D/ACP5/INPP5D/TCIRG1/TFRC/UBASH3B	20
GO:0044773	mitotic DNA damage checkpoint signaling	23/2053	81/18722	1.26236340658609e-05	0.000164656096511229	PRKDC/PLK3/CLSPN/CDK1/CCND1/BRCA1/MSH2/DTL/CHEK1/RPA2/TRIAP1/TOPBP1/BLM/SOX4/GTSE1/FANCD2/FOXO4/TIPIN/CDKN1A/CDK2/PLK2/BRCC3/MDC1	23
GO:0000077	DNA damage checkpoint signaling	29/2053	115/18722	1.29109698790878e-05	0.00016803865352392	PRKDC/PLK3/CLSPN/CDK1/CCND1/BRCA1/MSH2/DTL/CHEK1/RPA2/TRIAP1/TOPBP1/BLM/SOX4/FBXO6/WDR76/GTSE1/FANCD2/EIF2AK4/FOXO4/TIPIN/CDKN1A/CDK2/PLK2/PRPF19/E2F1/BRCC3/MAPK14/MDC1	29
GO:0042063	gliogenesis	58/2053	301/18722	1.31845045836398e-05	0.000171227332255063	VIM/S100A8/TSPO/CXCR4/CCL3/TNFRSF1B/TGFB1/C5AR1/LYN/CD9/TLR2/SPINT1/EGFR/LRP2/TNF/TLR4/IL1B/GSTP1/APP/GRN/ADGRG1/CCR2/LAMB1/DAG1/SOD1/CSK/CDK1/S100A9/NOTCH1/ITGB4/TREM2/C1QA/PTK2B/GPR183/IDH2/EZH2/CX3CR1/ASCL2/RHOA/STAT3/RHEB/PARD3/SOX4/HDAC2/IL6ST/CDK6/GPC1/BNIP3/GLI3/ID2/IFNGR1/MDK/PTN/PRPF19/HEXB/E2F1/ADGRG6/NDRG1	58
GO:0010810	regulation of cell-substrate adhesion	46/2053	221/18722	1.34307546943481e-05	0.000174048656946195	LGALS1/FLNA/FBLN1/FN1/RAC2/JAK2/VEGFA/ITGA6/CD36/MYADM/P4HB/GBP1/PREX1/DAG1/NOTCH1/BCL6/CALR/PTK2B/EMP2/RRAS/RASA1/KANK1/TACSTD2/S100A10/LIMS1/FERMT1/PLEKHA2/C1QBP/CCDC80/NRP1/RHOA/CIB1/ARL2/CDK6/CDKN2A/FERMT2/SLC9A1/VCL/CORO1C/STK4/MDK/PTN/TRIOBP/PTK2/ACTN4/RAC3	46
GO:0070301	cellular response to hydrogen peroxide	26/2053	98/18722	1.35553379106754e-05	0.000175284541948389	KLF4/LRRK2/PCNA/KLF2/TNFAIP3/RPS3/MET/STAT6/CDK1/EZH2/PAWR/TRPM2/SPHK1/HDAC2/TXN/SIRPA/NET1/APEX1/PARK7/ECT2/BNIP3/RHOB/TRAP1/KDM6B/SIGMAR1/PLEKHA1	26
GO:0022613	ribonucleoprotein complex biogenesis	81/2053	463/18722	1.37262522083172e-05	0.000177112931720222	RPS21/CELF2/SNRPG/ISG20/PA2G4/RPS5/RPS17/RPS7/RPSA/RPS27/PRKDC/SNRPD1/GLUL/RPS16/RPLP0/HSP90AA1/RAN/HSP90AB1/RPS14/RPL5/SNRPB/SNRPF/PSIP1/SNRPE/NPM1/RPL7A/POP7/RPL23A/EXOSC8/RPS19/NOP56/LSM2/RPL13A/C1QBP/RPL35/RPL3/LSM4/NHP2/RPL10A/SF1/MRPL20/SNRPD3/NOP58/RPL14/RBFA/RPS6/RPS8/SRSF10/SNU13/MRPL1/XRCC5/RPL7/SRPK1/IMP3/WDR18/SBDS/DDX1/KRR1/BRIX1/EIF5/MRPL36/EIF3J/USP39/AGO2/COIL/DENR/MALSU1/EIF3A/SF3A3/PRPF8/LUC7L3/SNRPD2/PRPF19/WBP11/RPS25/DDX18/FBL/PWP1/MRTO4/EIF3L/BMS1	81
GO:0042326	negative regulation of phosphorylation	70/2053	385/18722	1.41722189064219e-05	0.000182474921541912	PTPRC/TGFB1/PYCARD/LYN/SORL1/SLC8A1/FBLN1/CD300A/LILRB4/DUSP1/LRRK2/FBP1/TNFAIP3/IRAK3/IL1B/GSTP1/MYADM/ARRB2/SOCS3/PRKDC/PTPN6/CSK/BMP7/PKIB/PPIA/ENG/SAMSN1/HHEX/GADD45B/NR2F2/NPM1/SH2B3/LDLRAD4/CTDSPL/DDIT4/CDKN1C/NLRP12/PBK/TRIB1/CHP1/CALM2/CIB1/SUZ12/STAT3/PARD3/PRDX3/SIRPA/LRP5/PLPP3/CDKN2A/RASSF2/RGS2/PARK7/CORO1C/MVP/PARP14/CDKN1A/DMD/IPO5/IPO7/MIDN/VPS25/UBASH3B/MLLT1/PWP1/PKN1/EIF4G1/PRKAG2/PPARG/NCAPG2	70
GO:0018212	peptidyl-tyrosine modification	69/2053	378/18722	1.42201848646354e-05	0.000182700447939641	PTPRC/ITGB2/CD74/CD44/NCF1/FCGR1A/CSF1R/PECAM1/CLEC7A/TGFB1/LYN/CD300A/HCK/LILRB4/EFEMP1/EGFR/FGR/JAK2/VEGFA/ITGA5/CD4/TNFRSF14/TNF/CD36/APP/ARRB2/SOCS3/CD24/BTK/MET/JAK1/SYK/PTPN6/CSK/LILRA5/SAMSN1/PARP9/TREM2/IL6R/PTK2B/SH2B3/ICAM1/FLT1/WEE1/HBEGF/PBK/NRP1/ISL1/BAZ1B/SUZ12/HDAC2/IL6ST/EPHB4/TPST2/EFNA1/HCLS1/TTK/ARHGEF2/CSH1/MVP/PARP14/IGF1R/YES1/VPS25/INSR/PTK2/PDGFA/IL18/NCAPG2	69
GO:0048661	positive regulation of smooth muscle cell proliferation	27/2053	104/18722	1.4363111785547e-05	0.000184142458789065	AIF1/CYBA/TGFB1/EGFR/JAK2/TNF/TLR4/STAT1/PTAFR/HMOX1/NAMPT/TGM2/DNMT1/IL6R/GJA1/HBEGF/ADAMTS1/GNAI2/HPGD/AKR1B1/MYD88/PHB/JUN/ID2/SKP2/IL18/LDLRAP1	27
GO:0032733	positive regulation of interleukin-10 production	15/2053	41/18722	1.4915543288647e-05	0.000190411190918897	ISG15/LGALS9/CLEC7A/PYCARD/CD83/TLR2/HMGB1/TLR4/HSPD1/SASH3/CD46/SYK/LILRA5/TREM2/STAT3	15
GO:1902622	regulation of neutrophil migration	15/2053	41/18722	1.4915543288647e-05	0.000190411190918897	CD74/NCKAP1L/C5AR1/C3AR1/RAC2/CAMK1D/DPP4/ADAM8/CXCL8/C1QBP/JAM3/MYD88/RHOG/MPP1/MDK	15
GO:0090398	cellular senescence	25/2053	93/18722	1.54125732137196e-05	0.000195922540852368	SPI1/B2M/ABI3/NAMPT/PRKDC/VASH1/BCL6/CALR/PAWR/HRAS/EEF1E1/FBXO5/HMGA1/CDK6/CDKN2A/RBL1/CDKN1A/CDK2/ING2/ID2/YPEL3/PLK2/TBX3/YBX1/MAPK14	25
GO:1901992	positive regulation of mitotic cell cycle phase transition	25/2053	93/18722	1.54125732137196e-05	0.000195922540852368	AIF1/EGFR/APP/CDK1/CDC6/CCND1/ANAPC11/PHB2/DTL/UBE2C/ADAMTS1/CDT1/RAD51C/CCND3/RDX/CDCA5/FBXO5/RGCC/CDK4/BRD4/PBX1/TFDP1/APEX1/KMT2E/EIF4G1	25
GO:0030833	regulation of actin filament polymerization	38/2053	171/18722	1.58999672343282e-05	0.00020169091629169	TMSB4X/GMFG/CORO1A/NCKAP1L/CAPG/PYCARD/WAS/COTL1/HCK/TMSB10/MYADM/ARPC3/VASP/PREX1/ARPC5L/PTK2B/ICAM1/IQGAP2/RASA1/KANK1/RDX/RHOA/ACTR2/KANK4/TWF2/MYO1C/GRB2/SCIN/SPTBN1/ARPC4/ACTR3/ARPC1A/WASF2/PFN1/HCLS1/EPS8/DLG1/TRIOBP	38
GO:2001198	regulation of dendritic cell differentiation	8/2053	13/18722	1.59706744366638e-05	0.000202160435907137	HLA-B/LGALS9/LILRB2/LILRB1/HMGB1/TMEM176B/TMEM176A/CEBPB	8
GO:0098543	detection of other organism	10/2053	20/18722	1.60859547082046e-05	0.000203191006840479	HLA-B/HLA-A/HLA-DRB1/CLEC7A/TLR2/TLR1/TLR4/TLR6/CD1D/NAIP	10
GO:0031341	regulation of cell killing	26/2053	99/18722	1.64873213854338e-05	0.000207143414505587	HLA-B/TYROBP/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/HLA-F/SPI1/LGALS9/CLEC7A/NCKAP1L/B2M/HLA-E/HAVCR2/LILRB1/ITGAM/ARRB2/CADM1/SYK/HSP90AB1/CD1D/VAV1/CD59/P2RX7/ICAM1/CX3CR1	26
GO:0031342	negative regulation of cell killing	12/2053	28/18722	1.65024253556118e-05	0.000207143414505587	HLA-B/HLA-A/PTPRC/HLA-F/LGALS9/NCKAP1L/HLA-E/HAVCR2/LILRB1/ARRB2/HSP90AB1/CX3CR1	12
GO:0038094	Fc-gamma receptor signaling pathway	12/2053	28/18722	1.65024253556118e-05	0.000207143414505587	FCER1G/PTPRC/LYN/HCK/MYO1G/FGR/SYK/VAV1/RAP1A/VAV3/YES1/PTK2	12
GO:0030865	cortical cytoskeleton organization	19/2053	61/18722	1.6756281866083e-05	0.000209270544446807	PLEK/LCP1/NCKAP1L/FMNL1/RAC2/TNF/CALR/RHOBTB3/RHOA/ANLN/RHOG/RHOQ/ECT2/EZR/DLG1/RHOB/EPB41/RTKN/RAC3	19
GO:0090342	regulation of cell aging	19/2053	61/18722	1.6756281866083e-05	0.000209270544446807	B2M/ABI3/NAMPT/PRKDC/VASH1/BCL6/PAWR/EEF1E1/FBXO5/HMGA1/CDK6/CDKN2A/RBL1/ING2/YPEL3/PLK2/FOXM1/LMNA/YBX1	19
GO:0002887	negative regulation of myeloid leukocyte mediated immunity	7/2053	10/18722	1.6776521979819e-05	0.000209270544446807	SPI1/LGALS9/CD84/CD300A/HMOX1/CCR2/CX3CR1	7
GO:0010332	response to gamma radiation	18/2053	56/18722	1.71611926226071e-05	0.000212139671145023	PTPRC/CYBA/GPX1/PARP1/CXCL10/PRKDC/RAD51/HSPA5/HRAS/GATA3/BRCA2/FANCD2/XRCC5/YAP1/XRCC6/CDKN1A/TMEM109/XRCC2	18
GO:0032608	interferon-beta production	18/2053	56/18722	1.71611926226071e-05	0.000212139671145023	ISG15/PYCARD/LILRB1/OAS2/TLR2/HMGB1/TLR4/HMGB2/IRF7/TLR7/HSP90AA1/IRF1/OAS1/IRF5/TLR8/SIRPA/DDX58/REL	18
GO:0032648	regulation of interferon-beta production	18/2053	56/18722	1.71611926226071e-05	0.000212139671145023	ISG15/PYCARD/LILRB1/OAS2/TLR2/HMGB1/TLR4/HMGB2/IRF7/TLR7/HSP90AA1/IRF1/OAS1/IRF5/TLR8/SIRPA/DDX58/REL	18
GO:0051784	negative regulation of nuclear division	18/2053	56/18722	1.71611926226071e-05	0.000212139671145023	DUSP1/BMP7/CENPF/ZWINT/MAD2L1/CHEK1/CDT1/FBXO5/RAD21/AURKAIP1/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	18
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	11/2053	24/18722	1.71833133627469e-05	0.000212139671145023	HLA-B/HLA-A/PTPRC/HLA-F/LGALS9/NCKAP1L/HLA-E/HAVCR2/LILRB1/ARRB2/CX3CR1	11
GO:0071103	DNA conformation change	56/2053	290/18722	1.72937773229876e-05	0.00021306501835303	NASP/HMGB1/MCM7/HMGB2/HELLS/MCM3/MCM5/DNAJC9/MCM6/TOP2A/CENPW/CDK1/SMC2/HHEX/NUSAP1/NPM1/RAD51/ASF1B/RFC3/MCM4/RFC4/RFC2/SET/SMC4/NAP1L1/RBBP4/MCM2/HAT1/CDCA5/ITGB3BP/BLM/HMGA1/NCAPD3/NCAPH/DSCC1/CHD9/CHAF1A/HMGB3/XRCC5/RAD50/RPA1/SRPK1/XRCC6/HNRNPA2B1/KMT5A/MIS18A/NCAPG/DDX1/TOP2B/RNF8/POLQ/ASCC3/NAP1L4/PURA/SMARCA5/NCAPG2	56
GO:0010811	positive regulation of cell-substrate adhesion	30/2053	123/18722	1.86310117506625e-05	0.000229069816606506	FLNA/FN1/JAK2/VEGFA/ITGA6/CD36/MYADM/P4HB/PREX1/DAG1/CALR/PTK2B/EMP2/RRAS/S100A10/LIMS1/FERMT1/PLEKHA2/C1QBP/CCDC80/NRP1/CIB1/ARL2/CDK6/FERMT2/STK4/MDK/PTN/TRIOBP/RAC3	30
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	52/2053	264/18722	1.94107650118085e-05	0.000238168895850411	PTPRC/ITGB2/CD74/CD44/NCF1/FCGR1A/CSF1R/PECAM1/CLEC7A/TGFB1/LYN/CD300A/LILRB4/EGFR/JAK2/VEGFA/ITGA5/CD4/TNFRSF14/TNF/CD36/APP/ARRB2/SOCS3/CD24/SYK/PTPN6/LILRA5/SAMSN1/PARP9/TREM2/IL6R/PTK2B/SH2B3/ICAM1/HBEGF/NRP1/ISL1/SUZ12/HDAC2/IL6ST/EFNA1/HCLS1/ARHGEF2/CSH1/MVP/PARP14/YES1/VPS25/PDGFA/IL18/NCAPG2	52
GO:0043491	protein kinase B signaling	44/2053	211/18722	1.95167097424135e-05	0.000238778014219676	CCL3/TGFB1/MTDH/GPX1/KLF4/EGFR/LRP2/TNF/IL1B/ARRB2/PLK3/MET/HSP90AA1/HSP90AB1/DAG1/ITGB1/ENG/ZFP36L1/HPSE/ADAM8/SH2B3/RRAS/PIK3R5/CX3CR1/HBEGF/TPBG/C1QBP/PHLDA3/CIB1/MYDGF/TXN/GATA3/FERMT2/PHB/HCLS1/PARK7/DLG1/IGF1R/C1QTNF1/INSR/PTK2/PDGFA/IL18/PLEKHA1	44
GO:0048678	response to axon injury	23/2053	83/18722	1.95400008303102e-05	0.000238778014219676	TYROBP/AIF1/TSPO/LGALS1/FLNA/LYN/KLF4/SPP1/JAK2/GRN/DAG1/SOD1/CDK1/NREP/TREM2/DHFR/ISL1/FOLR1/JAM3/PTPRF/BNIP3/PTN/MTR	23
GO:0018108	peptidyl-tyrosine phosphorylation	68/2053	375/18722	2.04278846165534e-05	0.000249112916823243	PTPRC/ITGB2/CD74/CD44/NCF1/FCGR1A/CSF1R/PECAM1/CLEC7A/TGFB1/LYN/CD300A/HCK/LILRB4/EFEMP1/EGFR/FGR/JAK2/VEGFA/ITGA5/CD4/TNFRSF14/TNF/CD36/APP/ARRB2/SOCS3/CD24/BTK/MET/JAK1/SYK/PTPN6/CSK/LILRA5/SAMSN1/PARP9/TREM2/IL6R/PTK2B/SH2B3/ICAM1/FLT1/WEE1/HBEGF/PBK/NRP1/ISL1/BAZ1B/SUZ12/HDAC2/IL6ST/EPHB4/EFNA1/HCLS1/TTK/ARHGEF2/CSH1/MVP/PARP14/IGF1R/YES1/VPS25/INSR/PTK2/PDGFA/IL18/NCAPG2	68
GO:0061077	chaperone-mediated protein folding	20/2053	67/18722	2.04687779989765e-05	0.000249112916823243	CD74/PPIB/HSPE1/PDIA4/HSPA5/HSPA8/FKBP5/HSPA6/PDCD5/CCT2/SDF2L1/HSPA14/HSPA1A/FKBP1A/SGTB/TRAP1/P3H1/HSPA9/ST13/DNAJB14	20
GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	15/2053	42/18722	2.08613245561059e-05	0.000253376411612622	DUSP1/CENPF/ZWINT/MAD2L1/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	15
GO:1900407	regulation of cellular response to oxidative stress	24/2053	89/18722	2.13949609547252e-05	0.000259332860057275	PAGE4/GPX1/SOD2/LRRK2/ALOX5/TLR4/PARP1/CD36/P4HB/MET/TLR6/SOD1/BMP7/PPIA/TREM2/DHFR/MCL1/PAWR/TRPM2/TXN/FUT8/PARK7/GCH1/TRAP1	24
GO:0032613	interleukin-10 production	19/2053	62/18722	2.16966889190205e-05	0.000261405890590608	TYROBP/HLA-DRB1/ISG15/LGALS9/CLEC7A/PYCARD/LILRB1/CD83/TLR2/LILRB4/HMGB1/TLR4/HSPD1/SASH3/CD46/SYK/LILRA5/TREM2/STAT3	19
GO:0032653	regulation of interleukin-10 production	19/2053	62/18722	2.16966889190205e-05	0.000261405890590608	TYROBP/HLA-DRB1/ISG15/LGALS9/CLEC7A/PYCARD/LILRB1/CD83/TLR2/LILRB4/HMGB1/TLR4/HSPD1/SASH3/CD46/SYK/LILRA5/TREM2/STAT3	19
GO:0045576	mast cell activation	19/2053	62/18722	2.16966889190205e-05	0.000261405890590608	LGALS9/CD84/LYN/LAT2/CD300A/S100A12/RAC2/FGR/HMOX1/LCP2/CD300LF/STXBP2/ADGRE2/BTK/SYK/SNX4/PLSCR1/NDRG1/S100A13	19
GO:0071478	cellular response to radiation	40/2053	186/18722	2.17547181027986e-05	0.000261579776787157	TIMP1/CYBA/CRIP1/PCNA/IFI16/ADIRF/PARP1/NAMPT/CARD16/NUCKS1/MME/RAD51AP1/NPM1/RAD51/HSPA5/HAMP/PBK/CHEK1/HRAS/DDB1/TRIAP1/BLM/POLD3/GATA3/GRB2/XRCC5/YAP1/NET1/EIF2AK4/XRCC6/ECT2/ERCC1/NMT1/CDKN1A/RHOB/AURKB/PTN/MAPK14/TMEM109/FIGNL1	40
GO:0032633	interleukin-4 production	13/2053	33/18722	2.1987501879043e-05	0.000262276364362342	FCER1G/HLA-DRB1/LGALS9/CD86/HLA-E/HAVCR2/CD83/CEBPB/SASH3/SYK/NLRP3/RARA/GATA3	13
GO:0032673	regulation of interleukin-4 production	13/2053	33/18722	2.1987501879043e-05	0.000262276364362342	FCER1G/HLA-DRB1/LGALS9/CD86/HLA-E/HAVCR2/CD83/CEBPB/SASH3/SYK/NLRP3/RARA/GATA3	13
GO:0034110	regulation of homotypic cell-cell adhesion	13/2053	33/18722	2.1987501879043e-05	0.000262276364362342	LGALS1/LYN/PLAUR/CD9/JAK2/JAK1/SYK/SH2B3/RDX/IL6ST/ANK3/C1QTNF1/UBASH3B	13
GO:0036336	dendritic cell migration	13/2053	33/18722	2.1987501879043e-05	0.000262276364362342	CXCR4/SPI1/LGALS9/HMGB1/ALOX5/CCR1/CCR2/CALR/GPR183/NLRP12/C1QBP/TRPM2/EPS8	13
GO:0032271	regulation of protein polymerization	47/2053	232/18722	2.27253173395715e-05	0.000270290850947319	TMSB4X/GMFG/CORO1A/NCKAP1L/CAPG/PYCARD/WAS/COTL1/HCK/TMSB10/STMN1/MYADM/ARPC3/VASP/RPS3/MET/HSP90AA1/PREX1/ARPC5L/PTK2B/ICAM1/IQGAP2/RASA1/KANK1/CLIP1/RDX/RHOA/ACTR2/KANK4/ARL2/TWF2/MYO1C/GRB2/SCIN/SPTBN1/ARPC4/ACTR3/ARPC1A/WASF2/PFN1/HCLS1/EPS8/DLG1/HSPA1A/AKAP9/TRIOBP/DRG1	47
GO:0002218	activation of innate immune response	17/2053	52/18722	2.27945284298905e-05	0.000270290850947319	TYROBP/MNDA/FCN1/CLEC7A/PYCARD/LYN/HCK/HMGB1/IFI16/TLR4/PRKDC/LILRA2/HSP90AA1/SYK/AIM2/XRCC5/XRCC6	17
GO:0071357	cellular response to type I interferon	17/2053	52/18722	2.27945284298905e-05	0.000270290850947319	IFITM2/ISG15/SAMHD1/OAS2/IFITM3/IFIT1/STAT1/IRF7/JAK1/HSP90AB1/PTPN6/OAS1/IFI27/NLRC5/STAT2/MYD88/SP100	17
GO:0045739	positive regulation of DNA repair	21/2053	73/18722	2.39351629701831e-05	0.000283256366511043	WAS/HMGB1/EGFR/PCNA/PARP1/RPS3/PRKDC/FUS/RAD51AP1/PARP9/BRCA1/ACTR2/PNKP/DTX3L/TIMELESS/RNF8/RIF1/TRIM28/FOXM1/UBE2N/BRCC3	21
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	9/2053	17/18722	2.40570461756147e-05	0.000284138340656867	HLA-B/HLA-A/HLA-C/HLA-F/B2M/HLA-E/TAP2/TAP1/TAPBP	9
GO:0032508	DNA duplex unwinding	23/2053	84/18722	2.41447439716131e-05	0.000284613877857915	MCM7/MCM3/MCM5/MCM6/TOP2A/RAD51/RFC3/MCM4/RFC4/RFC2/MCM2/BLM/HMGA1/DSCC1/CHD9/XRCC5/RAD50/RPA1/XRCC6/DDX1/POLQ/ASCC3/PURA	23
GO:0071902	positive regulation of protein serine/threonine kinase activity	42/2053	200/18722	2.50478742027783e-05	0.000294680872973863	CSF1R/TGFB1/S100A12/EGFR/LRRK2/VEGFA/TNF/TLR4/IL1B/FGD2/MAGED1/RPS3/CD24/TLR6/SYK/HSP90AB1/CAMK1/CSK/CKS1B/ADAM8/PTK2B/CDC6/CCND1/PIK3R5/ERP29/FLT1/EZH2/DAZAP2/HRAS/CCND3/CKS2/RHOA/CALM2/CIB1/RGCC/RALB/DBF4/FERMT2/STK4/INSR/MAP3K4/PDGFA	42
GO:0046683	response to organophosphorus	31/2053	131/18722	2.58373862985135e-05	0.000303374398808378	SLC8A1/DUSP1/FOS/TYMS/HSP90B1/CASP1/AQP9/HSPD1/APP/STAT1/PTAFR/BSG/SOD1/ZFP36L1/KCNQ1/PTK2B/HSPA5/RFC3/P2RX7/FOSB/CDO1/SLC6A4/LDHA/ASS1/RAP1A/P2RY11/JUN/APEX1/EZR/NME1/AKAP9	31
GO:0022618	ribonucleoprotein complex assembly	45/2053	220/18722	2.62009796558636e-05	0.000307042730342152	CELF2/SNRPG/RPS5/RPSA/RPS27/PRKDC/SNRPD1/RPLP0/HSP90AA1/HSP90AB1/RPS14/RPL5/SNRPB/SNRPF/PSIP1/SNRPE/RPL23A/RPS19/LSM2/RPL13A/RPL3/LSM4/SF1/MRPL20/SNRPD3/SRSF10/SNU13/XRCC5/SRPK1/DDX1/BRIX1/EIF5/EIF3J/USP39/AGO2/COIL/DENR/EIF3A/SF3A3/PRPF8/LUC7L3/SNRPD2/PRPF19/MRTO4/EIF3L	45
GO:0016064	immunoglobulin mediated immune response	43/2053	207/18722	2.65987890916415e-05	0.000310649572264547	FCER1G/HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/HLA-DMA/CD74/HLA-DQB1/HLA-DMB/HLA-DQA1/TGFB1/HLA-DQA2/B2M/HLA-E/HLA-DRB5/TNF/HSPD1/GAPT/IRF7/C3/BTK/STAT6/CD46/IL27RA/PTPN6/UNG/BCL6/TREM2/C1QA/MSH2/TLR8/C1QBP/MSH6/MYD88/INPP5D/ERCC1/TCIRG1/RNF8/RIF1/TFRC/EXO1/SERPING1	43
GO:1901654	response to ketone	41/2053	194/18722	2.66123133573295e-05	0.000310649572264547	TXNIP/TSPO/CYBB/MSN/CYBA/TGFB1/TLR2/NASP/DUSP1/FOS/KLF4/EGFR/SPP1/PCNA/TYMS/KLF2/PARP1/SERPINF1/PTAFR/PTGER4/CLDN4/CALR/ATP2B1/ICAM1/CCND1/DDIT4/FOSB/AKR1B1/MTAP/HNRNPD/CDK4/ASS1/YAP1/ABHD2/GNAI1/PARK7/BAD/CDKN1A/TGFBR3/NME1/PTN	41
GO:0071826	ribonucleoprotein complex subunit organization	46/2053	227/18722	2.74255654637764e-05	0.000319121355123626	CELF2/SNRPG/RPS5/RPSA/RPS27/PRKDC/SNRPD1/RPLP0/HSP90AA1/HSP90AB1/RPS14/RPL5/SNRPB/SNRPF/PSIP1/SNRPE/RPL23A/RPS19/LSM2/RPL13A/RPL3/LSM4/SF1/MRPL20/SNRPD3/SRSF10/SNU13/XRCC5/SRPK1/DDX1/BRIX1/EIF5/EIF3J/USP39/AGO2/COIL/DENR/EIF3A/VCP/SF3A3/PRPF8/LUC7L3/SNRPD2/PRPF19/MRTO4/EIF3L	46
GO:0043434	response to peptide hormone	73/2053	414/18722	2.74444365406318e-05	0.000319121355123626	TIMP1/CYBB/CYBA/TNFSF10/LYN/SORL1/TLR2/UCP2/JAK2/RETN/GGH/FBN1/NR4A2/PARP1/IL1B/GSTP1/STAT1/SLC2A1/SOCS3/PRKDC/STAT6/DAG1/BSG/NUCKS1/CSK/BMP7/HHEX/ZFP36L1/ATP2B1/KCNQ1/PDK4/NR4A1/CDC6/ICAM1/STAT5A/PRKCB/BTG2/GJA1/KANK1/BTG1/GNAI2/CDO1/CCND3/STAT2/CCNA2/STAT3/SMARCC1/HADH/CDK4/CACYBP/LRP5/MYO1C/ASS1/GRB2/GNAI1/VPS13C/FOXO4/RHOQ/APEX1/SLC9A1/BCAR1/CSH1/CYC1/IGF1R/QDPR/GAB1/INSR/TGFBR3/MYO5A/PTK2/PPAT/SRSF4/PPARG	73
GO:0032753	positive regulation of interleukin-4 production	11/2053	25/18722	2.76467965424731e-05	0.000320733497128295	FCER1G/LGALS9/CD86/HLA-E/HAVCR2/CEBPB/SASH3/SYK/NLRP3/RARA/GATA3	11
GO:0150105	protein localization to cell-cell junction	10/2053	21/18722	2.76899919187428e-05	0.000320733497128295	PECAM1/FLNA/ACTB/DSP/JAK1/LSR/DLG5/TJP1/VCL/MPP7	10
GO:0033046	negative regulation of sister chromatid segregation	15/2053	43/18722	2.88069636235356e-05	0.000331114524408455	DUSP1/CENPF/ZWINT/MAD2L1/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	15
GO:0033048	negative regulation of mitotic sister chromatid segregation	15/2053	43/18722	2.88069636235356e-05	0.000331114524408455	DUSP1/CENPF/ZWINT/MAD2L1/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	15
GO:1904591	positive regulation of protein import	15/2053	43/18722	2.88069636235356e-05	0.000331114524408455	TGFB1/FLNA/JAK2/CDH1/RAN/HSP90AB1/CDK1/PDCD5/TPR/HCLS1/ECT2/IPO5/GLI3/TRIM28/MAPK14	15
GO:2000816	negative regulation of mitotic sister chromatid separation	15/2053	43/18722	2.88069636235356e-05	0.000331114524408455	DUSP1/CENPF/ZWINT/MAD2L1/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	15
GO:0051056	regulation of small GTPase mediated signal transduction	57/2053	302/18722	2.90486954661701e-05	0.000332693138568284	ARHGDIB/GPR65/STMN1/LPAR6/ARHGAP30/FBP1/FGD2/TAGAP/ADGRG1/CYTH4/DOCK2/TGM2/MET/PREX1/TIMP2/ITGB1/NOTCH1/BCL6/ARHGAP4/VAV1/DENND3/SPATA13/ARHGAP25/GMIP/RASA1/ARHGAP27/KANK1/HRAS/AMOT/RDX/NRP1/ABR/NOTCH2/CYTH1/ARHGAP26/ITGAV/FGD3/NET1/ARHGEF40/EPS8/SYDE2/ECT2/ARHGEF2/ARHGAP21/VAV3/ARHGAP10/ARHGAP23/FGD4/EPS8L2/CD2AP/FAM13A/FOXM1/GABARAP/CCDC125/ARFGEF3/RALGPS2/DYNLT1	57
GO:0032677	regulation of interleukin-8 production	26/2053	102/18722	2.90552007682968e-05	0.000332693138568284	TMSB4X/PTPRC/CD14/CD74/FCN1/LGALS9/CLEC7A/PYCARD/TLR2/HMGB1/KLF4/TLR1/TNF/TLR4/IL1B/LILRA2/TLR6/TLR7/SYK/CD33/TLR8/STAT3/MYD88/PARK7/HSPA1A/DDX58	26
GO:0045862	positive regulation of proteolysis	67/2053	372/18722	2.92403726186334e-05	0.000334175687070096	LAPTM5/S100A8/TNFSF10/TNFRSF1B/LGALS9/CLEC7A/PYCARD/LYN/FBLN1/FN1/HMGB1/JAK2/MBP/LRRK2/PERP/CASP1/IFI16/TNF/HSPD1/IL1B/APP/GRN/RPS3/PLK3/CTSH/CTSD/SYK/NLRP3/CLDN4/S100A9/TREM2/ADAM8/PTK2B/HSPE1/PSME2/AIM2/PSMC3/NLRP12/ASPH/PCOLCE2/PMAIP1/TRIB1/RHOA/NLRP1/STAT3/PSMC1/HDAC2/AURKAIP1/PDCD5/PSMD14/EFNA1/BAG2/CASP8AP2/PSMC2/MAGEF1/FIS1/TMTC3/HSPA1A/BAD/VCP/PICALM/PLK2/GABARAP/PTK2/PACSIN3/NDUFA13/PPARG	67
GO:0034340	response to type I interferon	18/2053	58/18722	2.93468118082496e-05	0.000334754507318436	IFITM2/ISG15/MX1/SAMHD1/OAS2/IFITM3/IFIT1/STAT1/IRF7/JAK1/HSP90AB1/PTPN6/OAS1/IFI27/NLRC5/STAT2/MYD88/SP100	18
GO:2000772	regulation of cellular senescence	17/2053	53/18722	3.01549618783421e-05	0.000343320249089284	B2M/ABI3/NAMPT/PRKDC/VASH1/BCL6/PAWR/EEF1E1/FBXO5/HMGA1/CDK6/CDKN2A/RBL1/ING2/YPEL3/PLK2/YBX1	17
GO:0001503	ossification	72/2053	408/18722	3.02234417516043e-05	0.000343448201722776	SRGN/CCL3/VCAN/ISG15/TGFB1/SLC8A1/MEF2C/EGFR/FBN2/FGR/JUNB/SPP1/SNX10/ALOX5/CLEC5A/CCR1/TNF/RRBP1/CEBPB/PTGER4/RUNX1/SLC26A2/GPNMB/BMP7/NOTCH1/CRIM1/CCDC47/ATP2B1/IL6R/PTK2B/HSPE1/NOTUM/P2RX7/BMP2K/ASGR2/RUNX3/TFAP2A/RHOA/CLIC1/FBXO5/IL6ST/PDLIM7/PBX1/LRP5/LGR4/ID3/ATRAID/YAP1/CDK6/SND1/FERMT2/MSX2/PHB/PSMC2/RASSF2/SBDS/ATP6V1B1/RBMX/FHL2/TCIRG1/GLI3/FOXC1/MDK/PTN/SMAD5/PTK2/FBL/MAPK14/SUCO/FIGNL1/PPARG/GPC3	72
GO:0033002	muscle cell proliferation	49/2053	248/18722	3.06015800629437e-05	0.000347087864608057	AIF1/CYBA/TGFB1/MEF2C/KLF4/EGFR/SOD2/JAK2/TNF/TNFAIP3/TLR4/GSTP1/STAT1/PTAFR/HMOX1/NAMPT/RUNX1/PRKDC/TGM2/DNMT1/CDK1/NOTCH1/IL6R/COMT/GJA1/HBEGF/ADAMTS1/GNAI2/HPGD/AKR1B1/TRIB1/RHOA/SF1/STAT3/MYD88/XRCC5/YAP1/PHB/XRCC6/JUN/CDKN1A/ID2/SKP2/FOXC1/TGFBR3/IL18/MAPK14/LDLRAP1/PPARG	49
GO:0050728	negative regulation of inflammatory response	38/2053	176/18722	3.14680239770558e-05	0.00035624178087233	PTPRC/HLA-DRB1/TNFRSF1B/ZFP36/LYN/HCK/GPX1/KLF4/FGR/ALOX5/AOAH/TNFAIP3/METRNL/SERPINF1/GSTP1/GRN/PTGER4/SOCS3/SYK/NLRP3/TNFAIP8L2/SOD1/SIGLEC10/TREM2/HAMP/RHBDF2/NLRP12/PBK/RPS19/ISL1/GATA3/SIRPA/ACP5/YES1/MDK/PLK2/MAPK14/PPARG	38
GO:0032743	positive regulation of interleukin-2 production	13/2053	34/18722	3.20382716783363e-05	0.000360402937834545	PTPRC/CLEC7A/CD86/CD83/CD4/IL1B/CCR2/RUNX1/SASH3/RPS3/PNP/SPTBN1/STOML2	13
GO:0050869	negative regulation of B cell activation	13/2053	34/18722	3.20382716783363e-05	0.000360402937834545	TYROBP/LAPTM5/MNDA/LYN/CD300A/TNFAIP3/BTK/SAMSN1/BCL6/PAWR/INPP5D/ID2/PKN1	13
GO:0009060	aerobic respiration	40/2053	189/18722	3.20586355545499e-05	0.000360402937834545	COX6A1/CDK1/IDH2/MSH2/NDUFA10/UQCRQ/NDUFB9/UQCC2/RHOA/NDUFB4/NDUFB7/NDUFA6/ARL2/NDUFAB1/FH/DHTKD1/PDHA1/COX7A2/NDUFV1/STOML2/MDH1/CHCHD10/CHCHD2/IDH1/NDUFS8/NDUFV2/COX6C/PARK7/CYC1/UQCR10/UQCRC2/NDUFS6/SUCLG1/BNIP3/COX5A/VCP/NDUFC2/NDUFB10/SDHA/NDUFA8	40
GO:0032388	positive regulation of intracellular transport	42/2053	202/18722	3.20758614672745e-05	0.000360402937834545	ITGB2/MSN/TGFB1/FLNA/SORL1/RAC2/JAK2/ITGAM/TCAF1/CDH1/OAZ1/IL1B/PLK3/RAN/HSP90AB1/CAMK1/CDK1/HRAS/CHP1/RDX/CIB1/PDCD5/MYO1C/ANK3/KIF20B/TMEM30B/TPR/SAE1/FIS1/YWHAE/HCLS1/ECT2/EZR/NMT1/IPO5/GLI3/TRIM28/B3GAT3/CTDSPL2/HUWE1/MAPK14/LDLRAP1	42
GO:1901653	cellular response to peptide	65/2053	359/18722	3.23303721450526e-05	0.000362583612841711	VIM/CYBA/LYN/SORL1/KLF4/UCP2/JAK2/FBN1/KLF2/TLR4/NR4A2/PARP1/IL1B/CD36/GSTP1/APP/ITGA4/STAT1/NAMPT/SOCS3/PRKDC/TLR6/STAT6/NUCKS1/CSK/ZFP36L1/ATP2B1/TREM2/RPL23/PDK4/NR4A1/CDC6/ICAM1/STAT5A/ID1/PRKCB/GJA1/KANK1/GNAI2/AKR1B1/CCND3/CCNA2/STAT3/SMARCC1/CDK4/MYO1C/ASS1/GRB2/KLF5/FIS1/FOXO4/RHOQ/APEX1/SLC9A1/BCAR1/ARHGEF2/CSH1/IGF1R/TIMELESS/GAB1/INSR/MYO5A/PTK2/PPAT/PPARG	65
GO:0071356	cellular response to tumor necrosis factor	46/2053	229/18722	3.44846864093112e-05	0.000386022609059454	LAPTM5/TMSB4X/CCL3L3/CCL3/TNFSF13B/CYBA/TNFRSF1B/ZFP36/CCL4/PYCARD/GBP2/ZFP36L2/JAK2/TNFRSF14/KLF2/CASP1/TNF/TNFAIP3/GSTP1/GBP1/STAT1/RPS3/KRT18/NFKBIA/SYK/CARD16/ZFP36L1/PTK2B/AIM2/HAMP/ICAM1/BRCA1/CXCL8/KRT8/BIRC3/LIMS1/SPHK1/CIB1/GATA3/ASS1/COMMD7/ARHGEF2/HSPA1A/PRPF8/MAPK14/ACTN4	46
GO:0032637	interleukin-8 production	26/2053	103/18722	3.48617618280684e-05	0.000389516891933725	TMSB4X/PTPRC/CD14/CD74/FCN1/LGALS9/CLEC7A/PYCARD/TLR2/HMGB1/KLF4/TLR1/TNF/TLR4/IL1B/LILRA2/TLR6/TLR7/SYK/CD33/TLR8/STAT3/MYD88/PARK7/HSPA1A/DDX58	26
GO:0048545	response to steroid hormone	62/2053	339/18722	3.57522015061574e-05	0.000398723436871644	AIF1/TXNIP/TSPO/CYBB/CYBA/ZFP36/TGFB1/ZFP36L2/TLR2/DUSP1/HMGB1/FOS/EGFR/SPP1/JAK2/PCNA/TYMS/TNF/HMGB2/HSPD1/PARP1/SERPINF1/GSTP1/PTAFR/IL1RN/RBBP7/AGL/CLDN4/BMP7/ENG/NOTCH1/CALR/ZFP36L1/ATP2B1/ICAM1/CCND1/CTSV/BRCA1/DDIT4/PHB2/FOSB/CDO1/ISL1/RHOA/ASS1/NCOR2/YAP1/ANXA3/ABHD2/PHB/IDH1/PGRMC2/PARK7/BAD/CDKN1A/SKP2/MDK/PTN/PKN1/PTPRU/ALAD/URI1	62
GO:1901989	positive regulation of cell cycle phase transition	28/2053	115/18722	3.60902489538333e-05	0.000401668905563201	AIF1/EGFR/APP/CDK1/NPM1/CDC6/CCND1/ANAPC11/PHB2/EZH2/ATAD5/DTL/UBE2C/ADAMTS1/CDT1/RAD51C/CCND3/RDX/CDCA5/FBXO5/RGCC/CDK4/BRD4/PBX1/TFDP1/APEX1/KMT2E/EIF4G1	28
GO:0045931	positive regulation of mitotic cell cycle	29/2053	121/18722	3.61502015006881e-05	0.000401668905563201	AIF1/EGFR/APP/CDK1/CDC6/CCND1/ANAPC11/PHB2/DTL/UBE2C/ADAMTS1/CDT1/RAD51C/CCND3/RDX/SPHK1/CDCA5/FBXO5/RGCC/CDK4/BRD4/PBX1/BRCA2/TFDP1/USP22/APEX1/KMT2E/EIF4G1/MEIS2	29
GO:0032728	positive regulation of interferon-beta production	14/2053	39/18722	3.6694965263237e-05	0.000406968191459191	ISG15/OAS2/TLR2/HMGB1/TLR4/HMGB2/IRF7/TLR7/HSP90AA1/IRF1/OAS1/IRF5/TLR8/DDX58	14
GO:0002292	T cell differentiation involved in immune response	21/2053	75/18722	3.7404939053901e-05	0.000414076816094846	FCER1G/HLA-DRA/HLA-DRB1/FGL2/LGALS9/CD86/HMGB1/PTGER4/STAT6/CD46/NLRP3/RARA/SEMA4A/BCL6/IL6R/GPR183/SPN/STAT3/GATA3/NFKBIZ/IL18	21
GO:0019724	B cell mediated immunity	43/2053	210/18722	3.81505119988432e-05	0.000420777705869595	FCER1G/HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/HLA-DMA/CD74/HLA-DQB1/HLA-DMB/HLA-DQA1/TGFB1/HLA-DQA2/B2M/HLA-E/HLA-DRB5/TNF/HSPD1/GAPT/IRF7/C3/BTK/STAT6/CD46/IL27RA/PTPN6/UNG/BCL6/TREM2/C1QA/MSH2/TLR8/C1QBP/MSH6/MYD88/INPP5D/ERCC1/TCIRG1/RNF8/RIF1/TFRC/EXO1/SERPING1	43
GO:0031396	regulation of protein ubiquitination	43/2053	210/18722	3.81505119988432e-05	0.000420777705869595	LAPTM5/TSPO/ISG15/RASSF5/LRRK2/TNFAIP3/ARRB2/RPS7/RPS3/HSP90AA1/HSP90AB1/RPL5/PPIA/RPL37/RPL23/NPM1/MAD2L1/HSPA5/BRCA1/UBE2C/UBB/BIRC3/FANCI/CHP1/SPHK1/SIAH2/FBXO5/UBE2S/SOX4/RPS2/UBE2D1/BAG2/DTX3L/UBXN2A/PARK7/COMMD1/HSPA1A/FKBP1A/SKP2/RPS20/GABARAP/HUWE1/UBE2N	43
GO:0048525	negative regulation of viral process	24/2053	92/18722	3.87214355598115e-05	0.000426291033685998	FCN1/BST2/IFITM2/APOBEC3A/ISG15/ZFP36/MX1/OAS2/IFITM3/OASL/IFIT1/IFI16/TNF/STAT1/ISG20/CIITA/PPIA/RSAD2/OAS1/APOBEC3G/APOBEC3C/PLSCR1/SRPK1/TRIM28	24
GO:0009262	deoxyribonucleotide metabolic process	15/2053	44/18722	3.93029942535574e-05	0.000431111454335182	TYMP/SAMHD1/DUT/UPP1/TYMS/RRM1/DPYD/UNG/DTYMK/RRM2/NUDT15/PNP/ADK/DCTPP1/DNPH1	15
GO:0097178	ruffle assembly	15/2053	44/18722	3.93029942535574e-05	0.000431111454335182	AIF1/ABI3/SNX10/ICAM1/KANK1/TACSTD2/HRAS/RDX/SH3YL1/PFN1/RHOG/EPS8/CORO1C/EPS8L2/COBL	15
GO:0006968	cellular defense response	17/2053	54/18722	3.95484538299494e-05	0.000433012268211125	TYROBP/MNDA/NCF2/LSP1/NCF1/C5AR1/LY96/LILRB2/CLEC5A/CCR2/CD300C/ITGB1/PTK2B/SPN/CX3CR1/LGALS3BP/TCIRG1	17
GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	16/2053	49/18722	4.01297199265435e-05	0.000438576174060585	SKIL/GPX1/TNFAIP3/HMGB2/HMOX1/LGALS3/TIMP3/ICAM1/BRCA1/PMAIP1/SP100/PARK7/ARHGEF2/ATF3/STK4/PEA15	16
GO:1902882	regulation of response to oxidative stress	25/2053	98/18722	4.04810086374508e-05	0.000441611003317645	PAGE4/GPX1/SOD2/LRRK2/ALOX5/TLR4/PARP1/CD36/P4HB/MET/TLR6/SOD1/BMP7/PPIA/MCTP1/TREM2/DHFR/MCL1/PAWR/TRPM2/TXN/FUT8/PARK7/GCH1/TRAP1	25
GO:0071260	cellular response to mechanical stimulus	22/2053	81/18722	4.12462440052543e-05	0.000449142402961027	CYBA/EGFR/CASP1/TLR4/IL1B/SLC2A1/PTGER4/CNN2/TLR7/DAG1/ENG/IRF1/GJA1/TLR8/CHEK1/MAP3K2/MYD88/CASP8AP2/TMEM150C/SLC9A1/BAD/BNIP3	22
GO:0051170	import into nucleus	35/2053	159/18722	4.16419816331681e-05	0.000452103246519991	TXNIP/TGFB1/FLNA/JAK2/LRRK2/CDH1/CD36/NFKBIA/RAN/SYK/HSP90AB1/CDK1/NOTCH1/RPL23/HNRNPA1/NUP214/PHB2/FERMT1/CHP1/KPNB1/STAT3/CSE1L/NXT1/TPR/RANBP17/HCLS1/ECT2/CDKN1A/IPO5/IPO7/GLI3/TRIM28/LMNA/NUP54/MAPK14	35
GO:0046598	positive regulation of viral entry into host cell	7/2053	11/18722	4.17441997620125e-05	0.000452103246519991	HLA-DRB1/LGALS1/CD74/LGALS9/CD4/P4HB/TRIM38	7
GO:0075294	positive regulation by symbiont of entry into host	7/2053	11/18722	4.17441997620125e-05	0.000452103246519991	HLA-DRB1/LGALS1/CD74/LGALS9/CD4/P4HB/TRIM38	7
GO:0034134	toll-like receptor 2 signaling pathway	9/2053	18/18722	4.34264926195777e-05	0.000469475595887326	CYBA/LYN/PIK3AP1/TLR2/HMGB1/TLR1/TNFAIP3/TLR6/TREM2	9
GO:0001889	liver development	33/2053	147/18722	4.51410549317916e-05	0.000487133686314298	EGFR/UCP2/PCNA/TYMS/TNFAIP3/HMOX1/CEBPB/MET/KRT18/RPS16/RARA/NOTCH1/HAMP/CCND1/EZH2/LSR/HRAS/SULF2/RPS6KA1/NOTCH2/HNRNPD/ASS1/RAP1A/SEC63/ARID5B/QDPR/GLI3/MDK/PTPN3/TGFBR3/PTN/COBL/E2F7	33
GO:2000403	positive regulation of lymphocyte migration	13/2053	35/18722	4.5875681516038e-05	0.00049417251184242	AIF1/CCL3/CCL4/PYCARD/TNFRSF14/APP/ITGA4/CCR2/CXCL10/ADAM8/PTK2B/SPN/RHOA	13
GO:0001666	response to hypoxia	57/2053	307/18722	4.70081038273065e-05	0.000505463482014048	CYBB/CXCR4/CYBA/SLC8A1/TLR2/UCP2/SOD2/VEGFA/HSP90B1/CASP1/NR4A2/HSPD1/P4HB/HMOX1/SLC2A1/PDLIM1/CD24/PLK3/CARD16/MALAT1/BMP7/DPP4/NOTCH1/ZFP36L1/TREM2/ADAM8/PTK2B/ICAM1/HILPDA/HK2/SLC29A1/DDIT4/BNIP3L/PHB2/KCNMB1/PMAIP1/EPAS1/ASCL2/SLC6A4/LDHA/RHOA/CCNA2/RGCC/CHCHD2/SOD3/FIS1/BACH1/SLC9A1/BAD/BNIP3/PLOD2/TGFBR3/PTN/LMNA/E2F1/NDRG1/ALAD	57
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	25/2053	99/18722	4.85869840604295e-05	0.000518916283109131	CD74/BCL2A1/CD44/TNFRSF1B/PYCARD/CRIP1/SKIL/IFI16/TNF/HMOX1/RPS3/PRKDC/BRCA1/DDIT4/MSH2/MCL1/MSH6/PHLDA3/TRIAP1/BRCA2/BAD/CDKN1A/ING2/E2F1/TMEM109	25
GO:0033209	tumor necrosis factor-mediated signaling pathway	25/2053	99/18722	4.85869840604295e-05	0.000518916283109131	LAPTM5/TMSB4X/TNFSF13B/TNFRSF1B/PYCARD/JAK2/TNFRSF14/CASP1/TNF/TNFAIP3/GSTP1/STAT1/KRT18/NFKBIA/SYK/CARD16/PTK2B/AIM2/KRT8/BIRC3/LIMS1/SPHK1/COMMD7/HSPA1A/ACTN4	25
GO:0042100	B cell proliferation	25/2053	99/18722	4.85869840604295e-05	0.000518916283109131	TYROBP/MNDA/PTPRC/CD74/TNFSF13B/NCKAP1L/LYN/MEF2C/CD300A/TLR4/HSPD1/GAPT/SASH3/BTK/BCL6/GPR183/SLC39A10/CD180/PAWR/INPP5D/VAV3/CDKN1A/TFRC/PKN1/CD320	25
GO:0030071	regulation of mitotic metaphase/anaphase transition	18/2053	60/18722	4.86916445650735e-05	0.000518916283109131	DUSP1/CENPF/ZWINT/MAD2L1/CDC6/ANAPC11/UBE2C/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	18
GO:0042306	regulation of protein import into nucleus	18/2053	60/18722	4.86916445650735e-05	0.000518916283109131	TGFB1/FLNA/JAK2/CDH1/CD36/RAN/HSP90AB1/CDK1/FERMT1/CHP1/TPR/HCLS1/ECT2/IPO5/GLI3/TRIM28/NUP54/MAPK14	18
GO:0062207	regulation of pattern recognition receptor signaling pathway	26/2053	105/18722	4.97104990534226e-05	0.000528835096313006	CYBA/LYN/TLR2/CD300A/HMGB1/TLR1/OASL/TNFAIP3/IRAK3/TLR4/CD36/CD300LF/IRF7/ARRB2/LILRA2/TLR6/RSAD2/TREM2/IRF1/SLC15A3/BIRC3/C1QBP/IFI35/USP15/LGR4/HSPA1A	26
GO:2001252	positive regulation of chromosome organization	22/2053	82/18722	5.05977399229027e-05	0.00053732113192463	FEN1/DNMT1/PKIB/HNRNPA1/CDT1/RAD21/HNRNPD/TCP1/CCT6A/TPR/CCT2/XRCC5/RAD50/PNKP/GNL3/HNRNPA2B1/ERCC1/CCT4/AURKB/TRIM28/CCT8/MAP3K4	22
GO:0051384	response to glucocorticoid	33/2053	148/18722	5.20734311659267e-05	0.000549553334601213	AIF1/ZFP36/ZFP36L2/DUSP1/HMGB1/FOS/EGFR/PCNA/TYMS/TNF/HSPD1/SERPINF1/GSTP1/PTAFR/IL1RN/AGL/ZFP36L1/ATP2B1/ICAM1/CCND1/CTSV/DDIT4/FOSB/CDO1/ISL1/RHOA/ASS1/ANXA3/BAD/CDKN1A/MDK/PTPRU/ALAD	33
GO:2001056	positive regulation of cysteine-type endopeptidase activity	33/2053	148/18722	5.20734311659267e-05	0.000549553334601213	LAPTM5/S100A8/TNFSF10/LGALS9/CLEC7A/PYCARD/HMGB1/JAK2/PERP/CASP1/IFI16/TNF/HSPD1/RPS3/CTSH/CTSD/SYK/NLRP3/S100A9/HSPE1/AIM2/NLRP12/ASPH/PMAIP1/RHOA/NLRP1/PDCD5/CASP8AP2/FIS1/BAD/VCP/NDUFA13/PPARG	33
GO:0051495	positive regulation of cytoskeleton organization	45/2053	226/18722	5.21235460040296e-05	0.000549553334601213	GMFG/CORO1A/PLEK/NCKAP1L/FLNA/PYCARD/WAS/HCK/GPR65/ARPC3/VASP/RPS3/MET/ARPC5L/DSTN/PTK2B/P2RX7/ICAM1/IQGAP2/ID1/CCDC88A/S100A10/CLIP1/HRAS/NRP1/RHOA/ACTR2/RGCC/ARL2/MYO1C/GRB2/SCIN/ARPC4/FERMT2/ACTR3/ARPC1A/WASF2/PFN1/HCLS1/DLG1/HSPA1A/CENPJ/AKAP9/GPSM2/DRG1	45
GO:0071241	cellular response to inorganic substance	45/2053	226/18722	5.21235460040296e-05	0.000549553334601213	TSPO/CYBB/NCF1/B2M/MEF2C/FOS/EGFR/ALOX5AP/JUNB/LRRK2/CDH1/FBP1/PARP1/SERPINF1/APP/HMOX1/HVCN1/FUS/MEF2A/SOD1/MT1X/CALR/HSD17B1/RAD51/HSPA5/FOSB/CAMK2D/TFAP2A/TRPM2/RASGRP2/MT2A/CCNA2/BLM/SYT7/HNRNPD/CACYBP/ANK3/JUN/ECT2/BAD/TIMELESS/BNIP3/CDK2/MTR/ALAD	45
GO:0034612	response to tumor necrosis factor	49/2053	253/18722	5.22075667871152e-05	0.000549553334601213	LAPTM5/TMSB4X/CCL3L3/CD14/CCL3/TNFSF13B/CYBA/TNFRSF1B/ZFP36/CCL4/PYCARD/GBP2/ZFP36L2/JAK2/TNFRSF14/KLF2/CASP1/TNF/TNFAIP3/CXCL16/GSTP1/GBP1/STAT1/RPS3/KRT18/NFKBIA/SYK/CARD16/ZFP36L1/PTK2B/AIM2/HAMP/ICAM1/BRCA1/CXCL8/KRT8/BIRC3/LIMS1/SPHK1/CIB1/GATA3/ASS1/COMMD7/ARHGEF2/GCH1/HSPA1A/PRPF8/MAPK14/ACTN4	49
GO:0051985	negative regulation of chromosome segregation	15/2053	45/18722	5.30174779350302e-05	0.000554824873858712	DUSP1/CENPF/ZWINT/MAD2L1/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	15
GO:1905819	negative regulation of chromosome separation	15/2053	45/18722	5.30174779350302e-05	0.000554824873858712	DUSP1/CENPF/ZWINT/MAD2L1/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	15
GO:0060337	type I interferon signaling pathway	16/2053	50/18722	5.30521026132884e-05	0.000554824873858712	IFITM2/ISG15/SAMHD1/OAS2/IFITM3/STAT1/IRF7/JAK1/HSP90AB1/PTPN6/OAS1/IFI27/NLRC5/STAT2/MYD88/SP100	16
GO:0050878	regulation of body fluid levels	67/2053	379/18722	5.31707170781265e-05	0.000554824873858712	FCER1G/SERPINA1/CYBA/PLEK/FLNA/LYN/PLAUR/WAS/CD9/FERMT3/OAS2/FBLN1/F5/FN1/ACTB/EGFR/JAK2/STMN1/VEGFA/PRDX2/TLR4/LMAN1/CD36/GNAS/MET/SYK/CLDN4/PTPN6/PPIA/HPSE/VAV1/FLI1/CD59/EMP2/SH2B3/ENTPD1/CCND1/STAT5A/HK2/SLC29A1/GJA1/LSR/GNAI2/AKR1B1/CDO1/ANXA5/GJA5/CLIC1/UMPS/IL6ST/VDR/PLSCR1/KCNN4/NCOR2/DGKD/VCL/ATP6V1B1/VAV3/C1QTNF1/MTX1/VKORC1/NME1/UBASH3B/PDGFA/PPAT/MAPK14/SERPING1	67
GO:0051346	negative regulation of hydrolase activity	67/2053	379/18722	5.31707170781265e-05	0.000554824873858712	TIMP1/SERPINA1/BST2/CD44/NCKAP1L/PLAUR/SORL1/CST3/ITIH5/SPINT1/GPX1/KLF4/SPINT2/LRRK2/VEGFA/IFI16/PEBP1/TNF/SERPINF1/APP/ARRB2/C3/PRDX5/CARD16/APLP2/TIMP2/LGALS3/IFI6/TIMP3/CRIM1/CST6/NR4A1/DHCR24/SERPINH1/GMIP/NAIP/CSTB/BIRC5/CNN3/BIRC3/GNAI2/HRAS/AMOT/CHP1/RDX/APOC1/TRIAP1/SIAH2/RPS6KA1/PRDX3/BCL2L12/ARL2/CSTA/USP14/RGS2/MASTL/PARK7/FKBP1A/PPP1R15A/SERPINB8/PICALM/GCHFR/PPP1R35/SERPING1/GAPDH/GPC3/URI1	67
GO:0045216	cell-cell junction organization	41/2053	200/18722	5.55680013843035e-05	0.000578833347753161	CSF1R/PECAM1/TGFB1/MTDH/FLNA/CD9/ACTB/VEGFA/CDH1/PERP/TNF/IL1B/DSP/GPBAR1/CLDN4/CSK/CLDN7/SVEP1/DSG2/GJA1/LSR/CNTNAP2/LIMS1/RDX/GJA5/RHOA/MARVELD3/PARD3/ARL2/DLG5/MYO1C/JAM3/TJP1/FERMT2/VCL/ECT2/PARD6B/DLG1/NUMB/CTNND1/MPP7	41
GO:0010389	regulation of G2/M transition of mitotic cell cycle	24/2053	94/18722	5.64269971363348e-05	0.000586762535213187	APP/CLSPN/CDK1/CENPF/CDC6/CCND1/BRCA1/NAE1/DTL/CHEK1/RAD51C/FBXO5/RAD21/TOPBP1/BLM/CDK4/BRD4/PBX1/FOXO4/CDKN1A/CDK2/AURKB/CHMP4C/BRCC3	24
GO:0006282	regulation of DNA repair	30/2053	130/18722	5.72496460394367e-05	0.00059428698310834	WAS/HMGB1/EGFR/PCNA/PARP1/DEK/RPS3/PRKDC/FUS/RAD51AP1/PARP9/RAD51/RMI2/BRCA1/CHEK1/RPA2/USP1/ACTR2/PNKP/DTX3L/MAGEF1/TIMELESS/RNF8/RIF1/POLQ/TRIM28/FOXM1/UBE2N/BRCC3/FIGNL1	30
GO:0006606	protein import into nucleus	34/2053	155/18722	5.73766674159721e-05	0.000594576864414219	TXNIP/TGFB1/FLNA/JAK2/LRRK2/CDH1/CD36/NFKBIA/RAN/SYK/HSP90AB1/CDK1/NOTCH1/RPL23/NUP214/PHB2/FERMT1/CHP1/KPNB1/STAT3/CSE1L/NXT1/TPR/RANBP17/HCLS1/ECT2/CDKN1A/IPO5/IPO7/GLI3/TRIM28/LMNA/NUP54/MAPK14	34
GO:1902806	regulation of cell cycle G1/S phase transition	36/2053	168/18722	5.9287127514314e-05	0.000613315112217042	AIF1/KLF4/EGFR/PRKDC/PLK3/GPNMB/PTPN6/PSME2/CDC6/CCND1/CTDSPL/PHB2/WEE1/EZH2/ADAMTS1/RPA2/CCND3/RDX/TRIAP1/SOX4/BRD7/RGCC/GTSE1/TFDP1/APEX1/RBL1/KMT2E/DLG1/CDKN1A/CDK2AP2/CDK2/ID2/PLK2/E2F1/EIF4G1/E2F7	36
GO:0023035	CD40 signaling pathway	8/2053	15/18722	6.51978404292738e-05	0.000672142684837874	CD86/ITGA5/TNFAIP3/ITGB1/TREM2/PHB2/PHB/FANCA	8
GO:0048569	post-embryonic animal organ development	8/2053	15/18722	6.51978404292738e-05	0.000672142684837874	EFEMP1/KLF4/VEGFA/FBN1/LDHA/HMGN1/ERCC1/MYO7A	8
GO:1901215	negative regulation of neuron death	42/2053	208/18722	6.53551790426949e-05	0.000672609046751577	CORO1A/HLA-F/TNFRSF1B/C5AR1/SORL1/MEF2C/SOD2/JAK2/LRRK2/NR4A2/HSPD1/SERPINF1/HMOX1/CEBPB/GRN/ARRB2/GPNMB/HSP90AB1/SOD1/ADAM8/PTK2B/NAIP/RASA1/PPT1/BTG2/SET/CX3CR1/MSH2/HRAS/NRP1/ISL1/RHOA/STAT3/PSMC1/GCLM/PARP2/NENF/PARK7/REL/MDK/EIF4G1/XRCC2	42
GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	11/2053	27/18722	6.5667766497321e-05	0.000673515553818677	PTPRC/LYN/HCK/MYO1G/FGR/SYK/VAV1/RAP1A/VAV3/YES1/PTK2	11
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	11/2053	27/18722	6.5667766497321e-05	0.000673515553818677	PTPRC/LYN/HCK/MYO1G/FGR/SYK/VAV1/RAP1A/VAV3/YES1/PTK2	11
GO:0042773	ATP synthesis coupled electron transport	24/2053	95/18722	6.7750267642927e-05	0.000692506994646614	COX6A1/CDK1/NDUFA10/UQCRQ/NDUFB9/NDUFB4/NDUFB7/NDUFA6/NDUFAB1/COX7A2/NDUFV1/CHCHD2/NDUFS8/NDUFV2/COX6C/PARK7/CYC1/UQCR10/NDUFS6/COX5A/NDUFC2/NDUFB10/SDHA/NDUFA8	24
GO:0042775	mitochondrial ATP synthesis coupled electron transport	24/2053	95/18722	6.7750267642927e-05	0.000692506994646614	COX6A1/CDK1/NDUFA10/UQCRQ/NDUFB9/NDUFB4/NDUFB7/NDUFA6/NDUFAB1/COX7A2/NDUFV1/CHCHD2/NDUFS8/NDUFV2/COX6C/PARK7/CYC1/UQCR10/NDUFS6/COX5A/NDUFC2/NDUFB10/SDHA/NDUFA8	24
GO:1903320	regulation of protein modification by small protein conjugation or removal	47/2053	242/18722	6.84592191431931e-05	0.000698563460644828	LAPTM5/TSPO/ISG15/RASSF5/LRRK2/TNFAIP3/ARRB2/RPS7/RPS3/HSP90AA1/HSP90AB1/RPL5/PPIA/RPL37/RPL23/NPM1/MAD2L1/HSPA5/BRCA1/UBE2C/UBB/BIRC3/EPAS1/FANCI/CHP1/SPHK1/SIAH2/FBXO5/UBE2S/SOX4/RPS2/UBE2D1/BAG2/DTX3L/GNL3/SAE1/UBXN2A/PARK7/COMMD1/HSPA1A/FKBP1A/SKP2/VCP/RPS20/GABARAP/HUWE1/UBE2N	47
GO:0061008	hepaticobiliary system development	33/2053	150/18722	6.89033032603161e-05	0.000701901221667057	EGFR/UCP2/PCNA/TYMS/TNFAIP3/HMOX1/CEBPB/MET/KRT18/RPS16/RARA/NOTCH1/HAMP/CCND1/EZH2/LSR/HRAS/SULF2/RPS6KA1/NOTCH2/HNRNPD/ASS1/RAP1A/SEC63/ARID5B/QDPR/GLI3/MDK/PTPN3/TGFBR3/PTN/COBL/E2F7	33
GO:0042307	positive regulation of protein import into nucleus	14/2053	41/18722	6.93898639641758e-05	0.000703191071429136	TGFB1/FLNA/JAK2/CDH1/RAN/HSP90AB1/CDK1/TPR/HCLS1/ECT2/IPO5/GLI3/TRIM28/MAPK14	14
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	14/2053	41/18722	6.93898639641758e-05	0.000703191071429136	FLNA/MYADM/P4HB/PREX1/CALR/S100A10/LIMS1/C1QBP/NRP1/CIB1/FERMT2/MDK/TRIOBP/RAC3	14
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	16/2053	51/18722	6.94987175595796e-05	0.000703191071429136	HLA-DRA/HLA-DRB1/LGALS9/NCKAP1L/CD86/CD83/HMGB1/RUNX1/SASH3/NLRP3/RARA/BCL6/RUNX3/GATA3/NFKBIZ/IL18	16
GO:0046850	regulation of bone remodeling	16/2053	51/18722	6.94987175595796e-05	0.000703191071429136	CSF1R/EGFR/SPP1/TNFAIP3/SYK/CSK/ADAM8/PDK4/HAMP/P2RX7/SYT7/INPP5D/TFRC/MDK/UBASH3B/SUCO	16
GO:0002708	positive regulation of lymphocyte mediated immunity	27/2053	113/18722	7.00046390983376e-05	0.000706072343571957	HLA-B/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/HLA-F/TGFB1/B2M/HLA-E/TNF/HSPD1/IL1B/SASH3/C3/CADM1/BTK/STAT6/NLRP3/CD1D/RSAD2/TREM2/VAV1/MSH2/GATA3/RIF1/TFRC/IL18	27
GO:0008637	apoptotic mitochondrial changes	26/2053	107/18722	7.00188407375524e-05	0.000706072343571957	TNFSF10/PYCARD/PLAUR/IFIT2/GPX1/SOD2/GGCT/HSPD1/ARRB2/SLC25A5/IFI6/HK2/BNIP3L/PMAIP1/TRIAP1/SLC25A4/PDCD5/GCLM/CHCHD10/FIS1/JUN/HSPA1A/BAD/NMT1/BNIP3/LMNA	26
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	21/2053	78/18722	7.03788090758908e-05	0.000708511500764001	CD44/PLAUR/GPX1/KLF4/VEGFA/TNF/ARRB2/PRDX5/CARD16/IFI6/NR4A1/DHCR24/NAIP/BIRC5/BIRC3/TRIAP1/SIAH2/RPS6KA1/PRDX3/BCL2L12/PARK7	21
GO:0031294	lymphocyte costimulation	15/2053	46/18722	7.07532616899699e-05	0.000709898946722106	LGALS1/TNFSF13B/LYN/CD86/LILRB2/LILRB4/TNFRSF14/CD24/PTPN6/CSK/DPP4/VAV1/MAP3K8/YES1/CD320	15
GO:0033047	regulation of mitotic sister chromatid segregation	15/2053	46/18722	7.07532616899699e-05	0.000709898946722106	DUSP1/CENPF/ZWINT/MAD2L1/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	15
GO:0071559	response to transforming growth factor beta	49/2053	256/18722	7.11265693943178e-05	0.000712453115802849	ZEB2/SPI1/TGFB1/ZFP36L2/PEG10/MEF2C/FOS/SKIL/FBN2/FBN1/PARP1/ARRB2/HSP90AB1/NREP/ENG/ZFP36L1/COL4A2/HSPA5/LDLRAD4/ID1/CDKN1C/CX3CR1/RUNX3/HPGD/LIMS1/FERMT1/LTBP1/USP15/ITGB5/STAT3/HDAC2/ZYX/PDCD5/FOLR1/SDCBP/FUT8/FERMT2/JUN/HSPA1A/FKBP1A/YES1/ING2/ZNF451/TGFBR3/EID2/SMAD5/PTK2/ITGB8/PPARG	49
GO:0070482	response to oxygen levels	62/2053	347/18722	7.24891149166597e-05	0.000724891149166597	CYBB/CXCR4/CYBA/SLC8A1/TLR2/UCP2/SOD2/VEGFA/HSP90B1/CASP1/NR4A2/HSPD1/P4HB/HMOX1/NAMPT/SLC2A1/PDLIM1/CD24/PLK3/CARD16/MALAT1/BMP7/DPP4/NOTCH1/ZFP36L1/TREM2/ADAM8/PTK2B/ICAM1/HILPDA/HK2/SLC29A1/DDIT4/BNIP3L/PHB2/KCNMB1/PMAIP1/EPAS1/ASCL2/SLC6A4/LDHA/RHOA/CCNA2/HDAC2/RGCC/CDK4/CYB5R4/CHCHD2/SOD3/FIS1/BACH1/SLC9A1/BAD/CDKN1A/BNIP3/PLOD2/TGFBR3/PTN/LMNA/E2F1/NDRG1/ALAD	62
GO:1904666	regulation of ubiquitin protein ligase activity	10/2053	23/18722	7.30457484851832e-05	0.000729242081382861	RPS7/RPL5/RPL37/RPL23/MAD2L1/UBE2C/FBXO5/UBE2S/BAG2/RPS20	10
GO:1902905	positive regulation of supramolecular fiber organization	42/2053	209/18722	7.32735371153556e-05	0.000730301034372315	GMFG/CORO1A/PLEK/NCKAP1L/FLNA/PYCARD/WAS/HCK/GPR65/GPX1/APP/ARPC3/VASP/RPS3/MET/ARPC5L/DSTN/PTK2B/ICAM1/IQGAP2/ID1/CCDC88A/S100A10/CLIP1/NRP1/RHOA/ACTR2/RGCC/ARL2/MYO1C/GRB2/SCIN/ARPC4/FERMT2/ACTR3/ARPC1A/WASF2/PFN1/DLG1/HSPA1A/AKAP9/DRG1	42
GO:0032273	positive regulation of protein polymerization	31/2053	138/18722	7.47240875738598e-05	0.000743523259441391	GMFG/CORO1A/NCKAP1L/PYCARD/WAS/HCK/ARPC3/VASP/RPS3/MET/HSP90AA1/ARPC5L/PTK2B/ICAM1/IQGAP2/CLIP1/RHOA/ACTR2/ARL2/MYO1C/GRB2/SCIN/ARPC4/ACTR3/ARPC1A/WASF2/PFN1/DLG1/HSPA1A/AKAP9/DRG1	31
GO:0006970	response to osmotic stress	22/2053	84/18722	7.51600409302379e-05	0.00074613991098288	TSPO/TSC22D3/EGFR/TNF/AQP9/SLC2A1/PLK3/RCSD1/HSP90AB1/ZFP36L1/LRRC8C/PTK2B/AKR1B1/MARVELD3/XRCC5/XRCC6/ARHGEF2/BAD/EFHD1/PKN1/NFAT5/MAP7	22
GO:0051017	actin filament bundle assembly	34/2053	157/18722	7.52357743574404e-05	0.00074613991098288	AIF1/MARCKS/PLEK/LCP1/FLNA/PHACTR1/WAS/GPR65/STMN1/HSP90B1/PTGER4/PDLIM1/MET/CALD1/PTK2B/ID1/CCDC88A/TACSTD2/S100A10/PAWR/RDX/NRP1/RHOA/ITGB5/RGCC/ZYX/TJP1/FERMT2/WASF2/PFN1/EPS8/SLC9A1/EZR/LIMA1	34
GO:0071560	cellular response to transforming growth factor beta stimulus	48/2053	250/18722	7.7470258411833e-05	0.000767032261503297	ZEB2/SPI1/TGFB1/ZFP36L2/PEG10/MEF2C/FOS/SKIL/FBN2/FBN1/PARP1/ARRB2/HSP90AB1/NREP/ENG/ZFP36L1/COL4A2/HSPA5/LDLRAD4/ID1/CDKN1C/CX3CR1/HPGD/LIMS1/FERMT1/LTBP1/USP15/ITGB5/STAT3/HDAC2/ZYX/PDCD5/FOLR1/SDCBP/FUT8/FERMT2/JUN/HSPA1A/FKBP1A/YES1/ING2/ZNF451/TGFBR3/EID2/SMAD5/PTK2/ITGB8/PPARG	48
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	18/2053	62/18722	7.85721733399775e-05	0.000775383289539251	DUSP1/CENPF/ZWINT/MAD2L1/CDC6/ANAPC11/UBE2C/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	18
GO:0046824	positive regulation of nucleocytoplasmic transport	18/2053	62/18722	7.85721733399775e-05	0.000775383289539251	TGFB1/FLNA/JAK2/CDH1/IL1B/RAN/HSP90AB1/CAMK1/CDK1/TPR/YWHAE/HCLS1/ECT2/IPO5/GLI3/TRIM28/CTDSPL2/MAPK14	18
GO:0035456	response to interferon-beta	12/2053	32/18722	8.05537954718857e-05	0.000792332414477565	MNDA/BST2/IFITM2/XAF1/IFITM3/IFI16/STAT1/IRF1/AIM2/OAS1/PLSCR1/NDUFA13	12
GO:0090022	regulation of neutrophil chemotaxis	12/2053	32/18722	8.05537954718857e-05	0.000792332414477565	CD74/NCKAP1L/C5AR1/C3AR1/RAC2/CAMK1D/DPP4/CXCL8/C1QBP/JAM3/MPP1/MDK	12
GO:0010769	regulation of cell morphogenesis involved in differentiation	24/2053	96/18722	8.10632647316062e-05	0.000796038606202352	FLNA/FBLN1/MYADM/P4HB/GBP1/PRKDC/PREX1/CALR/KANK1/TACSTD2/S100A10/LIMS1/C1QBP/NRP1/ACTR2/CIB1/FERMT2/OBSL1/CORO1C/MDK/TRIOBP/PTK2/ACTN4/RAC3	24
GO:2001242	regulation of intrinsic apoptotic signaling pathway	35/2053	164/18722	8.13303130178395e-05	0.000797356009978819	S100A8/CD74/CD44/PYCARD/PLAUR/SKIL/GPX1/SOD2/LRRK2/HELLS/PARP1/P4HB/RPS7/RPS3/SOD1/PPIA/S100A9/TREM2/ERP29/UBB/PMAIP1/MCL1/TRIAP1/SIAH1/FIS1/PARK7/ARHGEF2/HSPA1A/BAD/ING2/TRAP1/RTKN2/NDUFA13/FIGNL1/URI1	35
GO:0043405	regulation of MAP kinase activity	37/2053	177/18722	8.18723419341384e-05	0.000801360606206902	TGFB1/LYN/SORL1/CD300A/S100A12/DUSP1/EGFR/LRRK2/VEGFA/TNF/IRAK3/TLR4/IL1B/GSTP1/FGD2/MAGED1/RPS3/CD24/TLR6/SYK/PTPN6/CSK/BMP7/ADAM8/PTK2B/SH2B3/PIK3R5/ERP29/FLT1/EZH2/HRAS/TRIB1/RGS2/INSR/MAP3K4/PDGFA/PPARG	37
GO:0070374	positive regulation of ERK1 and ERK2 cascade	43/2053	217/18722	8.49037690624557e-05	0.000829678525040284	PTPRC/CCL3L3/HLA-DRB1/CD74/CCL3/CD44/CSF1R/CCL4/LGALS9/TGFB1/PYCARD/C5AR1/HAVCR2/SCIMP/HMGB1/EGFR/CD4/CCR1/TNF/TLR4/CD36/APP/ARRB2/GPNMB/GLIPR2/GPBAR1/NOTCH1/TREM2/PTK2B/MARCO/GPR183/ICAM1/PHB2/TPBG/GNAI2/HRAS/NRP1/CIB1/NOTCH2/RAP1A/FERMT2/PHB/PDGFA	43
GO:0051783	regulation of nuclear division	31/2053	139/18722	8.6228024336909e-05	0.000841249017921063	DUSP1/IL1B/MKI67/BMP7/RAD51AP1/CENPF/ZWINT/NUSAP1/CALR/MAD2L1/ANAPC11/CHEK1/CDT1/SPHK1/PKMYT1/FBXO5/RAD21/RGCC/AURKAIP1/LRP5/BUB3/KIF20B/TPR/NDC80/OBSL1/TTK/AURKB/LCMT1/INSR/BUB1B/KNTC1	31
GO:0043410	positive regulation of MAPK cascade	80/2053	480/18722	8.69775957665967e-05	0.000847184374349968	LAPTM5/PTPRC/CCL3L3/HLA-DRB1/CD74/CCL3/CD44/NCF1/CSF1R/SPI1/CCL4/LGALS9/CLEC7A/TGFB1/PYCARD/C5AR1/HAVCR2/S100A12/SCIMP/HMGB1/EGFR/LRRK2/VEGFA/CD4/PRDX2/CCR1/TNF/TLR4/IL1B/CD36/APP/FGD2/ARRB2/MAGED1/RPS3/CD24/GPNMB/GLIPR2/TLR6/GPBAR1/SYK/SOD1/CSK/LILRA5/TIMP2/PPIA/NOTCH1/GADD45B/TREM2/ADAM8/PTK2B/MARCO/GPR183/ICAM1/PIK3R5/ERP29/PHB2/FLT1/EZH2/TPBG/GNAI2/HRAS/NRP1/SPHK1/CIB1/NOTCH2/MYDGF/SDCBP/MYD88/EFNA1/RAP1A/FERMT2/PHB/NENF/RASSF2/IGF1R/C1QTNF1/INSR/MAP3K4/PDGFA	80
GO:0060249	anatomical structure homeostasis	57/2053	314/18722	8.94462268889223e-05	0.000869817441383361	LYZ/CORO1A/CSF1R/PECAM1/B2M/RAC2/ACTB/EGFR/SPP1/MBP/VEGFA/SNX10/TNFAIP3/TLR4/SLC2A1/CCR2/SASH3/CTSH/SYK/SOD1/CSK/ITGB1/NOTCH1/ATP2B1/ADAM8/PTK2B/PDK4/LAMC1/HAMP/P2RX7/OAS1/GJA1/TPP1/LSR/AKR1B1/ALDOA/ALDH1A1/EPAS1/BARD1/FH/JAM3/LIPA/RAB3D/PRDX1/YAP1/TJP1/ACP5/INPP5D/VCL/DMD/TCIRG1/GAA/TFRC/FOXC1/UBASH3B/HOMER1/RAC3	57
GO:0032206	positive regulation of telomere maintenance	16/2053	52/18722	9.02561349505528e-05	0.000876273154859736	PKIB/HNRNPA1/HNRNPD/TCP1/CCT6A/CCT2/XRCC5/RAD50/PNKP/GNL3/HNRNPA2B1/ERCC1/CCT4/AURKB/CCT8/MAP3K4	16
GO:0046677	response to antibiotic	15/2053	47/18722	9.3466313576876e-05	0.000903416080400748	CRIP1/MEF2C/JAK2/JAK1/HSP90AA1/SOD1/CIITA/RPL23/HSPA5/EZH2/ACTR2/CYB5R4/SLC9A1/KDM6B/SLC1A3	15
GO:0097028	dendritic cell differentiation	15/2053	47/18722	9.3466313576876e-05	0.000903416080400748	HLA-B/SPI1/LGALS9/LYN/LILRB2/LILRB1/HMGB1/TMEM176B/TMEM176A/CEBPB/IRF8/TREM2/TRPM2/NOTCH2/ITGB8	15
GO:0030890	positive regulation of B cell proliferation	14/2053	42/18722	9.36541336682109e-05	0.000903416080400748	PTPRC/CD74/TNFSF13B/NCKAP1L/MEF2C/TLR4/SASH3/BCL6/GPR183/SLC39A10/VAV3/CDKN1A/TFRC/CD320	14
GO:0045687	positive regulation of glial cell differentiation	14/2053	42/18722	9.36541336682109e-05	0.000903416080400748	CXCR4/TNFRSF1B/TGFB1/TLR2/SPINT1/DAG1/NOTCH1/RHEB/HDAC2/IL6ST/ID2/MDK/PTN/PRPF19	14
GO:0050673	epithelial cell proliferation	74/2053	437/18722	9.45517900113728e-05	0.000910611139756399	CYBA/ZFP36/TGFB1/C5AR1/B2M/MEF2C/HMGB1/GPX1/EGFR/VEGFA/ALOX5/TNF/TNFAIP3/HMGB2/SERPINF1/ITGA4/STAT1/HMOX1/CEBPB/GRN/MAGED1/PRKDC/LAMB1/NRP2/GPBAR1/VASH1/GLUL/STAT6/JAML/NOTCH1/NR2F2/ZFP36L1/TNFSF12/NR4A1/LAMC1/CCND1/LGR5/STAT5A/ID1/PHB2/FLT1/CDKN1C/GJA1/RUNX3/FERMT1/HRAS/SULF2/NRP1/ISL1/MARVELD3/RPS6KA1/SUZ12/NOTCH2/STAT3/MYDGF/RGCC/VDR/GATA3/BRCA2/LGR4/YAP1/CDK6/HMGN1/DLG1/BAD/ID2/UHRF1/MDK/TGFBR3/NME1/PTN/PURA/PPARG/GPC3	74
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	24/2053	97/18722	9.66636098209994e-05	0.000929457786740379	GPX1/ITGA6/PRDX2/TNF/TNFAIP3/HMGB2/IL1B/GSTP1/HMOX1/LGALS3/IFI6/ICAM1/BRCA1/MCL1/NRP1/SIAH2/ITGAV/GCLM/YAP1/PARK7/ARHGEF2/HSPA1A/LMNA/PEA15	24
GO:0036293	response to decreased oxygen levels	58/2053	322/18722	9.71833660973224e-05	0.000932428994245643	CYBB/CXCR4/CYBA/SLC8A1/TLR2/UCP2/SOD2/VEGFA/HSP90B1/CASP1/NR4A2/HSPD1/P4HB/HMOX1/NAMPT/SLC2A1/PDLIM1/CD24/PLK3/CARD16/MALAT1/BMP7/DPP4/NOTCH1/ZFP36L1/TREM2/ADAM8/PTK2B/ICAM1/HILPDA/HK2/SLC29A1/DDIT4/BNIP3L/PHB2/KCNMB1/PMAIP1/EPAS1/ASCL2/SLC6A4/LDHA/RHOA/CCNA2/RGCC/CHCHD2/SOD3/FIS1/BACH1/SLC9A1/BAD/BNIP3/PLOD2/TGFBR3/PTN/LMNA/E2F1/NDRG1/ALAD	58
GO:0045589	regulation of regulatory T cell differentiation	11/2053	28/18722	9.74806342948977e-05	0.000932428994245643	HLA-DRA/HLA-DRB1/LGALS9/LILRB2/LILRB4/CD46/IL4I1/BCL6/IRF1/MDK/FANCA	11
GO:0061082	myeloid leukocyte cytokine production	11/2053	28/18722	9.74806342948977e-05	0.000932428994245643	LAPTM5/CD74/TGFB1/LILRB1/IRAK3/TLR4/CD36/HMOX1/BCL6/DDX1/DDX58	11
GO:0014013	regulation of gliogenesis	25/2053	103/18722	9.7594234731044e-05	0.000932428994245643	TSPO/CXCR4/TNFRSF1B/TGFB1/LYN/TLR2/SPINT1/EGFR/LRP2/TNF/IL1B/DAG1/NOTCH1/TREM2/IDH2/EZH2/ASCL2/RHEB/HDAC2/IL6ST/ID2/MDK/PTN/PRPF19/E2F1	25
GO:0051881	regulation of mitochondrial membrane potential	20/2053	74/18722	9.7924795077414e-05	0.000934099794061183	TSPO/UCP2/LRRK2/CASP1/PARP1/SOD1/IFI6/BNIP3L/UBB/PMAIP1/CLIC1/SLC25A36/PRDX3/GCLM/HEBP2/STOML2/PARK7/BAD/BNIP3/VCP	20
GO:1902099	regulation of metaphase/anaphase transition of cell cycle	18/2053	63/18722	9.88413036400503e-05	0.00094134574895286	DUSP1/CENPF/ZWINT/MAD2L1/CDC6/ANAPC11/UBE2C/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	18
GO:0045861	negative regulation of proteolysis	62/2053	351/18722	0.000101687398123457	0.000966916622410053	TIMP1/SERPINA1/BST2/CD44/PLAUR/SORL1/CST3/ITIH5/SPINT1/GPX1/KLF4/SPINT2/LRRK2/VEGFA/IFI16/PEBP1/TNF/SERPINF1/APP/ARRB2/RPS7/C3/CTSZ/PRDX5/HSP90AB1/RPL5/CARD16/APLP2/TIMP2/IFI6/TIMP3/CRIM1/RPL23/CST6/NR4A1/DHCR24/SERPINH1/NAIP/CSTB/BIRC5/PBK/BIRC3/TRIAP1/SIAH2/RPS6KA1/PRDX3/SMARCC1/BCL2L12/SDCBP/CSTA/EFNA1/USP14/SVIP/PARK7/SERPINB8/DNAJC1/PICALM/PTPN3/SERPING1/GAPDH/GPC3/ALAD	62
GO:0072001	renal system development	55/2053	302/18722	0.000107850092912924	0.00102389328714801	PECAM1/MEF2C/LRRK2/VEGFA/FBN1/LRP2/SERPINF1/STAT1/MAGED1/CD24/CTSH/MME/RARA/BMP7/LAMA5/CENPF/NOTCH1/IL6R/LGR5/HSPB11/ENPEP/TACSTD2/ADAMTS1/HPGD/AKR1B1/TFAP2A/ADAMTS6/SULF2/NRP1/FRAS1/RHOA/NOTCH2/SOX4/AHI1/GATA3/DLG5/PBX1/ASS1/COL4A1/LGR4/ID3/C1GALT1/YAP1/CNTRL/ARID5B/DLG1/GLI3/FOXC1/SMAD5/BASP1/PDGFA/PPAT/IRX2/ASXL1/GPC3	55
GO:0002763	positive regulation of myeloid leukocyte differentiation	17/2053	58/18722	0.000108106332967657	0.00102470457789248	TYROBP/HLA-DRB1/CD74/EVI2B/TGFB1/FOS/CD4/CCR1/TNF/RUNX1/ZFP36L1/TREM2/TRIB1/NOTCH2/HCLS1/JUN/ID2	17
GO:2000117	negative regulation of cysteine-type endopeptidase activity	22/2053	86/18722	0.000109818224019606	0.00103928918630542	CD44/PLAUR/GPX1/KLF4/VEGFA/IFI16/TNF/ARRB2/PRDX5/CARD16/IFI6/NR4A1/DHCR24/NAIP/BIRC5/BIRC3/TRIAP1/SIAH2/RPS6KA1/PRDX3/BCL2L12/PARK7	22
GO:0050678	regulation of epithelial cell proliferation	66/2053	381/18722	0.000112293645156838	0.00106104231644256	CYBA/ZFP36/TGFB1/C5AR1/B2M/MEF2C/HMGB1/GPX1/EGFR/VEGFA/ALOX5/TNF/TNFAIP3/HMGB2/SERPINF1/ITGA4/STAT1/HMOX1/GRN/MAGED1/PRKDC/LAMB1/NRP2/GPBAR1/VASH1/GLUL/JAML/NOTCH1/NR2F2/ZFP36L1/TNFSF12/NR4A1/LAMC1/CCND1/STAT5A/ID1/PHB2/FLT1/CDKN1C/GJA1/RUNX3/HRAS/SULF2/NRP1/ISL1/MARVELD3/SUZ12/NOTCH2/STAT3/MYDGF/RGCC/VDR/GATA3/BRCA2/YAP1/CDK6/HMGN1/DLG1/BAD/UHRF1/MDK/TGFBR3/NME1/PTN/PPARG/GPC3	66
GO:0006213	pyrimidine nucleoside metabolic process	10/2053	24/18722	0.000112947487858351	0.00106554233828633	APOBEC3A/TYMP/UPP1/DPYD/CDA/DTYMK/TK1/APOBEC3G/APOBEC3C/ERH	10
GO:0006119	oxidative phosphorylation	31/2053	141/18722	0.0001141308286405	0.00107501565438461	COX6A1/CDK1/MSH2/NDUFA10/UQCRQ/NDUFB9/UQCC2/RHOA/NDUFB4/NDUFB7/NDUFA6/NDUFAB1/COX7A2/NDUFV1/STOML2/CHCHD10/CHCHD2/NDUFS8/NDUFV2/COX6C/PARK7/CYC1/UQCR10/UQCRC2/NDUFS6/COX5A/VCP/NDUFC2/NDUFB10/SDHA/NDUFA8	31
GO:1904029	regulation of cyclin-dependent protein kinase activity	24/2053	98/18722	0.000114884993988636	0.00108042314095896	ACTB/EGFR/TNFAIP3/HSP90AB1/CKS1B/HHEX/NR2F2/CDC6/CCND1/CCNE1/CDKN1C/CCND3/CKS2/CCNA2/PKMYT1/CCNE2/BLM/RGCC/CDKN2A/CCNI/CDKN1A/IPO5/IPO7/HERC5	24
GO:0007566	embryo implantation	16/2053	53/18722	0.000116245831414211	0.00109151015412405	TIMP1/ARHGDIB/FBLN1/SPP1/VEGFA/IL1B/BSG/SOD1/ITGB4/CALR/EMP2/VMP1/GJA1/C1QBP/AGO2/TRIM28	16
GO:0034121	regulation of toll-like receptor signaling pathway	20/2053	75/18722	0.000119932015449601	0.00112436264484001	CYBA/LYN/TLR2/CD300A/HMGB1/TLR1/TNFAIP3/IRAK3/CD36/CD300LF/IRF7/ARRB2/LILRA2/TLR6/RSAD2/TREM2/IRF1/BIRC3/IFI35/LGR4	20
GO:0051051	negative regulation of transport	78/2053	470/18722	0.000122109050002675	0.00114182439817812	CD74/CORO1A/BST2/HLA-F/TNFRSF1B/SPI1/LGALS9/NCKAP1L/CD84/LILRB2/LILRB1/TLR2/CD300A/HMGB1/UCP2/LRRK2/OAZ1/TNF/LMAN1/IL1B/CD36/HMOX1/CD300LF/CCR2/CNN2/LRPAP1/CSK/LGALS3/NOTCH1/RSAD2/MCTP1/PTK2B/COMT/PNKD/HAMP/ICAM1/CD33/RHBDF2/ERP29/PRKCB/IDH2/GJA1/CAMK2D/KCNE3/GNAI2/FERMT1/CHP1/APOC1/BARD1/KLF7/CALM2/FABP5/FRMD4A/C4orf3/RIN3/TXN/HADH/ITGAV/SIRPA/SDCBP/ANK3/PLSCR1/TPR/RAP1A/SVIP/VDAC1/GOPC/SP100/FIS1/YWHAE/RGS2/PARK7/GABRE/COMMD1/MIDN/PICALM/PACSIN3/PEA15	78
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	15/2053	48/18722	0.000122284975828949	0.00114182439817812	PTPRC/TNFSF10/PYCARD/SKIL/TNF/G0S2/PDIA3/TIMP3/TNFSF12/PMAIP1/ITM2C/TNFRSF12A/ATF3/STK4/PEA15	15
GO:0007094	mitotic spindle assembly checkpoint signaling	13/2053	38/18722	0.000122746122804148	0.00114182439817812	DUSP1/CENPF/ZWINT/MAD2L1/CDT1/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	13
GO:0071173	spindle assembly checkpoint signaling	13/2053	38/18722	0.000122746122804148	0.00114182439817812	DUSP1/CENPF/ZWINT/MAD2L1/CDT1/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	13
GO:0071174	mitotic spindle checkpoint signaling	13/2053	38/18722	0.000122746122804148	0.00114182439817812	DUSP1/CENPF/ZWINT/MAD2L1/CDT1/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	13
GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	29/2053	129/18722	0.000123837142212656	0.00115019017534975	LAPTM5/S100A8/TNFSF10/LGALS9/CLEC7A/PYCARD/HMGB1/JAK2/CASP1/TNF/HSPD1/RPS3/CTSH/CTSD/SYK/NLRP3/S100A9/HSPE1/NLRP12/PMAIP1/RHOA/NLRP1/PDCD5/CASP8AP2/FIS1/BAD/VCP/NDUFA13/PPARG	29
GO:0006284	base-excision repair	14/2053	43/18722	0.000124959664034607	0.00115703392624636	HMGB1/PCNA/RPS3/RPA3/FEN1/UNG/LIG1/RPA2/PARP2/PNKP/RPA1/APEX1/POLQ/HUWE1	14
GO:0006458	'de novo' protein folding	14/2053	43/18722	0.000124959664034607	0.00115703392624636	CD74/HSPD1/HSPE1/HSPA5/HSPA8/HSPA6/CCT2/SDF2L1/HSPA14/HSPA1A/FKBP1A/HSPA9/ST13/DNAJB14	14
GO:0061572	actin filament bundle organization	34/2053	161/18722	0.000126733805217467	0.00117165305285794	AIF1/MARCKS/PLEK/LCP1/FLNA/PHACTR1/WAS/GPR65/STMN1/HSP90B1/PTGER4/PDLIM1/MET/CALD1/PTK2B/ID1/CCDC88A/TACSTD2/S100A10/PAWR/RDX/NRP1/RHOA/ITGB5/RGCC/ZYX/TJP1/FERMT2/WASF2/PFN1/EPS8/SLC9A1/EZR/LIMA1	34
GO:0050852	T cell receptor signaling pathway	28/2053	123/18722	0.000128007978175306	0.00118161210623359	HLA-A/LAPTM5/HLA-DPB1/PTPRC/HLA-DRB1/HLA-DQB1/CD300A/LILRB4/THEMIS2/GBP1/LCP2/PRAM1/RPS3/PTPN6/CSK/LGALS3/PAWR/HRAS/GATA3/KCNN4/STOML2/NFKBIZ/BCAR1/INPP5D/PHPT1/EZR/BTN3A1/UBE2N	28
GO:0001776	leukocyte homeostasis	22/2053	87/18722	0.000131963121879863	0.00121252485647654	CD74/CORO1A/TNFSF13B/TSC22D3/LGALS9/NCKAP1L/LYN/MEF2C/HMGB1/SKIL/DOCK10/TNFAIP3/GAPT/CCR2/SH2B3/GPR183/PMAIP1/RPS6/JAM3/TCIRG1/DOCK11/PKN1	22
GO:0019646	aerobic electron transport chain	22/2053	87/18722	0.000131963121879863	0.00121252485647654	COX6A1/NDUFA10/UQCRQ/NDUFB9/NDUFB4/NDUFB7/NDUFA6/NDUFAB1/COX7A2/NDUFV1/NDUFS8/NDUFV2/COX6C/PARK7/CYC1/UQCR10/NDUFS6/COX5A/NDUFC2/NDUFB10/SDHA/NDUFA8	22
GO:2000177	regulation of neural precursor cell proliferation	22/2053	87/18722	0.000131963121879863	0.00121252485647654	FLNA/LYN/SPINT1/SPINT2/LRRK2/VEGFA/LRP2/ADGRG1/CTSZ/NOTCH1/BTG2/ASPM/CX3CR1/NAP1L1/GNAI2/SLC6A4/RHOA/SHCBP1/GLI3/ID2/MDK/PTN	22
GO:2001022	positive regulation of response to DNA damage stimulus	25/2053	105/18722	0.000135775690513703	0.00124564853682296	WAS/HMGB1/SKIL/EGFR/PCNA/PARP1/RPS3/PRKDC/FUS/RAD51AP1/PARP9/BRCA1/PMAIP1/ACTR2/EEF1E1/PNKP/DTX3L/TIMELESS/RNF8/RIF1/TRIM28/FOXM1/UBE2N/BRCC3/NSMCE4A	25
GO:0045123	cellular extravasation	19/2053	70/18722	0.000136298696994577	0.00124853768239308	PECAM1/ITGAL/TNF/ITGA4/PTAFR/CCR2/PTGER4/SELPLG/IL27RA/JAML/ITGB1/ADAM8/SPN/ICAM1/CX3CR1/SIRPA/JAM3/SELL/MDK	19
GO:0003158	endothelium development	30/2053	136/18722	0.000137106736861247	0.0012540250322675	CXCR4/MSN/PECAM1/GPX1/VEGFA/TNF/IL1B/MYADM/CXCL10/MET/ITGAX/NOTCH1/NR2F2/FSTL1/ICAM1/ID1/GJA1/BTG1/RDX/GJA5/NRP1/RHOA/MYD88/TJP1/RAP1A/VCL/EZR/RHOB/KDM6B/PTN	30
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	11/2053	29/18722	0.000141561743170671	0.00129280130749471	HLA-DRB1/LYN/HCK/GPX1/FGR/SYK/TREM2/RHBDF2/YES1/PLK2/MAPK14	11
GO:0009411	response to UV	32/2053	149/18722	0.000142179443924207	0.0012964690935338	TIMP1/CRIP1/GPX1/EGFR/PCNA/PARP1/FEN1/CARD16/MME/NPM1/CCND1/MSH2/DTL/PBK/CHEK1/USP1/MSH6/DDB1/TRIAP1/SCARA3/POLD3/BRCA2/HMGN1/EIF2AK4/TIPIN/ERCC1/CDKN1A/AURKB/PTN/MAP3K4/TP53I13/UBE4B	32
GO:1905475	regulation of protein localization to membrane	36/2053	175/18722	0.000142547552700593	0.00129785328710706	ITGB2/TGFB1/ACTB/ABI3/EGFR/ITGAM/TCAF1/TNF/GBP1/DAG1/CSK/ITGB1/LGALS3/TREM2/HRAS/CHP1/CIB1/PDCD5/MYO1C/ANK3/SPTBN1/RAP1A/GOPC/RHOG/FIS1/RHOQ/EZR/DLG1/GPC1/NMT1/NUMB/PICALM/PTN/AP2M1/LDLRAP1/GPC3	36
GO:0060759	regulation of response to cytokine stimulus	34/2053	162/18722	0.000143785627298101	0.00130714206634637	LAPTM5/PTPRC/CD74/CXCR4/ISG15/SAMHD1/PYCARD/TLR2/KLF4/CASP1/TNFAIP3/IRAK3/TLR4/GSTP1/IL1RN/CD300LF/IRF7/CD24/SYK/HSP90AB1/CARD16/PTPN6/PARP9/TREM2/SH2B3/AGPAT2/OAS1/NLRC5/SPHK1/STAT2/HSPA1A/PARP14/DDX58/PPARG	34
GO:0001649	osteoblast differentiation	44/2053	229/18722	0.000148201250815375	0.0013452458470382	CCL3/VCAN/MEF2C/FBN2/JUNB/SPP1/CLEC5A/TNF/RRBP1/CEBPB/GPNMB/BMP7/NOTCH1/CRIM1/CCDC47/IL6R/HSPE1/CLIC1/FBXO5/IL6ST/PDLIM7/LRP5/LGR4/ID3/ATRAID/YAP1/CDK6/SND1/FERMT2/MSX2/PHB/PSMC2/RASSF2/RBMX/FHL2/TCIRG1/GLI3/SMAD5/PTK2/FBL/MAPK14/SUCO/FIGNL1/PPARG	44
GO:0051101	regulation of DNA binding	27/2053	118/18722	0.000152987965579295	0.00138358990622643	TMSB4X/TGFB1/PLAUR/HMGB1/KLF4/JAK2/IFI16/HMGB2/PARP1/HMOX1/NFKBIA/ID1/CDT1/ISL1/CALM2/HDAC2/TXN/GATA3/MSX2/SP100/JUN/PARK7/FOXC1/TRIM28/NME1/E2F1/PPARG	27
GO:0001910	regulation of leukocyte mediated cytotoxicity	21/2053	82/18722	0.000153348463163273	0.00138358990622643	HLA-B/TYROBP/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/HLA-F/SPI1/LGALS9/NCKAP1L/B2M/HLA-E/HAVCR2/LILRB1/ITGAM/ARRB2/CADM1/CD1D/VAV1/ICAM1/CX3CR1	21
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	21/2053	82/18722	0.000153348463163273	0.00138358990622643	SPI1/SKIL/GPX1/TNF/TNFAIP3/HMGB2/HMOX1/LGALS3/TIMP3/ICAM1/BRCA1/PMAIP1/CASP8AP2/SP100/PARK7/ARHGEF2/BAD/ATF3/STK4/GABARAP/PEA15	21
GO:0010965	regulation of mitotic sister chromatid separation	18/2053	65/18722	0.000153578479591133	0.00138358990622643	DUSP1/CENPF/ZWINT/MAD2L1/CDC6/ANAPC11/UBE2C/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	18
GO:0044784	metaphase/anaphase transition of cell cycle	18/2053	65/18722	0.000153578479591133	0.00138358990622643	DUSP1/CENPF/ZWINT/MAD2L1/CDC6/ANAPC11/UBE2C/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	18
GO:0002526	acute inflammatory response	26/2053	112/18722	0.000156778591817825	0.00141030217527279	S100A8/SERPINA1/HLA-E/FN1/ALOX5AP/TNF/TREM1/IL1B/GSTP1/CEBPB/C3/BTK/NLRP3/ADAM8/IL6R/HAMP/ICAM1/CD163/STAT3/IL6ST/GATA3/ASS1/PLSCR1/PARK7/EIF2AK1/PTGES	26
GO:0055094	response to lipoprotein particle	12/2053	34/18722	0.000158737691103605	0.00142578764464316	FCER1G/CD68/ITGB2/CD9/TLR4/CD36/TLR6/SYK/ITGB1/TREM2/MYD88/PPARG	12
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	23/2053	94/18722	0.000160333343440176	0.00143796720574149	ACTB/EGFR/TNFAIP3/CKS1B/HHEX/NR2F2/CDC6/CCND1/CCNE1/CDKN1C/CCND3/CKS2/CCNA2/PKMYT1/CCNE2/BLM/RGCC/CDKN2A/CCNI/CDKN1A/IPO5/IPO7/HERC5	23
GO:0045333	cellular respiration	44/2053	230/18722	0.000164175992453451	0.00147023276823986	SCO2/COX6A1/CDK1/IDH2/MSH2/NDUFA10/UQCRQ/NDUFB9/UQCC2/CISD1/RHOA/NDUFB4/NDUFB7/NDUFA6/ARL2/NDUFAB1/FH/DHTKD1/PDHA1/COX7A2/NDUFV1/STOML2/MDH1/CHCHD10/CHCHD2/IDH1/NDUFS8/NDUFV2/COX6C/PARK7/CYC1/UQCR10/UQCRC2/NDUFS6/SUCLG1/BNIP3/COX5A/VCP/TRAP1/UQCRFS1/NDUFC2/NDUFB10/SDHA/NDUFA8	44
GO:0031295	T cell costimulation	14/2053	44/18722	0.000164932776599096	0.00147480873262977	LGALS1/TNFSF13B/LYN/CD86/LILRB2/LILRB4/TNFRSF14/CD24/PTPN6/CSK/DPP4/VAV1/MAP3K8/YES1	14
GO:0031577	spindle checkpoint signaling	13/2053	39/18722	0.000165771701574602	0.00148010447834466	DUSP1/CENPF/ZWINT/MAD2L1/CDT1/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	13
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	10/2053	25/18722	0.000169814615402271	0.00151170280773535	LY96/SCIMP/LY86/PRDX2/TNFAIP3/CD36/LILRA2/CARD16/CD180/TRIB1	10
GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	10/2053	25/18722	0.000169814615402271	0.00151170280773535	ITGB2/ALOX5/TNF/ITGA4/PTAFR/CCR2/ICAM1/RHOA/MDK/NFAT5	10
GO:0001822	kidney development	53/2053	293/18722	0.000170195802325302	0.00151285157622491	PECAM1/MEF2C/LRRK2/VEGFA/FBN1/LRP2/SERPINF1/STAT1/MAGED1/CD24/CTSH/MME/RARA/BMP7/LAMA5/CENPF/NOTCH1/IL6R/HSPB11/ENPEP/TACSTD2/ADAMTS1/HPGD/AKR1B1/TFAP2A/ADAMTS6/SULF2/NRP1/FRAS1/RHOA/NOTCH2/SOX4/AHI1/GATA3/DLG5/PBX1/ASS1/LGR4/ID3/C1GALT1/YAP1/CNTRL/ARID5B/DLG1/GLI3/FOXC1/SMAD5/BASP1/PDGFA/PPAT/IRX2/ASXL1/GPC3	53
GO:0002200	somatic diversification of immune receptors	20/2053	77/18722	0.000177388978109539	0.00157355917605703	PTPRC/TGFB1/SAMHD1/HMGB1/HMGB2/HSPD1/PRKDC/STAT6/IL27RA/UNG/BCL6/MSH2/MSH6/CTNNBL1/ERCC1/RNF8/RIF1/TFRC/POLQ/EXO1	20
GO:0034135	regulation of toll-like receptor 2 signaling pathway	7/2053	13/18722	0.000177812186894444	0.00157355917605703	CYBA/LYN/HMGB1/TLR1/TNFAIP3/TLR6/TREM2	7
GO:0070486	leukocyte aggregation	7/2053	13/18722	0.000177812186894444	0.00157355917605703	S100A8/MSN/CD44/RAC2/IL1B/BMP7/S100A9	7
GO:2001234	negative regulation of apoptotic signaling pathway	43/2053	224/18722	0.000178876767587321	0.00158064890356985	CD74/CD44/PLAUR/GPX1/SOD2/LRRK2/ITGA6/PRDX2/TNF/TNFAIP3/HMGB2/NR4A2/HELLS/IL1B/GSTP1/HMOX1/ARRB2/SLC25A5/PPIA/LGALS3/IFI6/ICAM1/BRCA1/CX3CR1/GNAI2/MCL1/NRP1/TRIAP1/SIAH2/ITGAV/GCLM/YAP1/PARK7/ARHGEF2/HSPA1A/ING2/TRAP1/RTKN2/LMNA/PEA15/NDUFA13/FIGNL1/URI1	43
GO:0071456	cellular response to hypoxia	32/2053	151/18722	0.000184373315742675	0.00162682337420007	CYBB/SLC8A1/VEGFA/P4HB/HMOX1/PLK3/CARD16/MALAT1/BMP7/NOTCH1/ZFP36L1/TREM2/ADAM8/ICAM1/HILPDA/SLC29A1/BNIP3L/PHB2/KCNMB1/PMAIP1/EPAS1/CCNA2/RGCC/CHCHD2/BACH1/SLC9A1/BAD/BNIP3/PTN/LMNA/E2F1/NDRG1	32
GO:0010951	negative regulation of endopeptidase activity	47/2053	252/18722	0.000186988502072262	0.00164747578918292	TIMP1/SERPINA1/BST2/CD44/PLAUR/SORL1/CST3/ITIH5/SPINT1/GPX1/KLF4/SPINT2/VEGFA/IFI16/PEBP1/TNF/SERPINF1/APP/ARRB2/C3/PRDX5/CARD16/APLP2/TIMP2/IFI6/TIMP3/CRIM1/CST6/NR4A1/DHCR24/SERPINH1/NAIP/CSTB/BIRC5/BIRC3/TRIAP1/SIAH2/RPS6KA1/PRDX3/BCL2L12/CSTA/USP14/PARK7/SERPINB8/PICALM/SERPING1/GAPDH	47
GO:0098869	cellular oxidant detoxification	24/2053	101/18722	0.000189221037320312	0.00166470120809658	GPX1/SOD2/ALOX5AP/MGST3/PRDX2/CD36/GSTP1/PRDX4/GLRX/PRDX5/SOD1/BMP7/S100A9/DHFR/GPX8/TXN/PRDX3/PRDX6/PRDX1/MGST1/SOD3/PARK7/GCH1/PTGES	24
GO:0072678	T cell migration	18/2053	66/18722	0.000189778183287393	0.00166715827192439	AIF1/CCL3/MSN/PYCARD/MYO1G/ITGAL/TNFRSF14/CXCL16/APP/ITGA4/CCR2/CXCL10/IL27RA/ADAM8/GPR183/SPN/ICAM1/RHOA	18
GO:2001235	positive regulation of apoptotic signaling pathway	28/2053	126/18722	0.000197726661725204	0.00173444440109828	S100A8/PTPRC/TNFSF10/PYCARD/SKIL/TNF/G0S2/RPS7/MAGED1/RPS3/CTSH/SOD1/PDIA3/S100A9/TIMP3/TNFSF12/UBB/PMAIP1/MCL1/ITM2C/TNFRSF12A/SIAH1/FIS1/PARK7/BAD/ATF3/STK4/PEA15	28
GO:0010001	glial cell differentiation	43/2053	225/18722	0.000198126994974301	0.00173541893408147	VIM/S100A8/CXCR4/TNFRSF1B/TGFB1/C5AR1/LYN/CD9/TLR2/SPINT1/EGFR/TNF/TLR4/GSTP1/APP/GRN/DAG1/SOD1/CSK/CDK1/S100A9/NOTCH1/ITGB4/TREM2/C1QA/RHOA/STAT3/RHEB/PARD3/SOX4/HDAC2/IL6ST/CDK6/GPC1/BNIP3/GLI3/ID2/IFNGR1/MDK/PTN/PRPF19/ADGRG6/NDRG1	43
GO:0000076	DNA replication checkpoint signaling	8/2053	17/18722	0.000201223547757194	0.00173919902097514	CLSPN/CDC6/NAE1/CDT1/TOPBP1/CDC45/TIPIN/TIMELESS	8
GO:0007076	mitotic chromosome condensation	8/2053	17/18722	0.000201223547757194	0.00173919902097514	SMC2/NUSAP1/SMC4/CDCA5/NCAPD3/NCAPH/KMT5A/NCAPG	8
GO:0016045	detection of bacterium	8/2053	17/18722	0.000201223547757194	0.00173919902097514	HLA-B/HLA-A/HLA-DRB1/TLR2/TLR1/TLR6/CD1D/NAIP	8
GO:0045591	positive regulation of regulatory T cell differentiation	8/2053	17/18722	0.000201223547757194	0.00173919902097514	HLA-DRA/HLA-DRB1/LGALS9/LILRB2/LILRB4/CD46/IL4I1/BCL6	8
GO:0061450	trophoblast cell migration	8/2053	17/18722	0.000201223547757194	0.00173919902097514	TIMP1/ARHGDIB/VEGFA/ITGB4/CALR/GJA1/C1QBP/AGO2	8
GO:0043304	regulation of mast cell degranulation	11/2053	30/18722	0.000201493667512811	0.00173919902097514	LGALS9/CD84/LYN/CD300A/RAC2/FGR/HMOX1/STXBP2/ADGRE2/SYK/SNX4	11
GO:0045577	regulation of B cell differentiation	11/2053	30/18722	0.000201493667512811	0.00173919902097514	NCKAP1L/ZFP36L2/BTK/SYK/PTPN6/IL4I1/ZFP36L1/NFAM1/INPP5D/BAD/ID2	11
GO:0046825	regulation of protein export from nucleus	11/2053	30/18722	0.000201493667512811	0.00173919902097514	IL1B/CAMK1/IFI27/BARD1/PTPN14/TXN/TPR/SP100/YWHAE/PARK7/CTDSPL2	11
GO:1902751	positive regulation of cell cycle G2/M phase transition	11/2053	30/18722	0.000201493667512811	0.00173919902097514	APP/CDK1/NPM1/CCND1/ATAD5/DTL/RAD51C/FBXO5/CDK4/BRD4/PBX1	11
GO:0007179	transforming growth factor beta receptor signaling pathway	39/2053	198/18722	0.000201747086433116	0.00173919902097514	ZEB2/SPI1/TGFB1/PEG10/FOS/SKIL/FBN2/FBN1/PARP1/ARRB2/HSP90AB1/NREP/ENG/HSPA5/LDLRAD4/ID1/CDKN1C/HPGD/FERMT1/LTBP1/USP15/ITGB5/STAT3/ZYX/FOLR1/SDCBP/FUT8/FERMT2/JUN/HSPA1A/FKBP1A/ING2/ZNF451/TGFBR3/EID2/SMAD5/PTK2/ITGB8/PPARG	39
GO:0050864	regulation of B cell activation	39/2053	198/18722	0.000201747086433116	0.00173919902097514	TYROBP/LAPTM5/MNDA/PTPRC/CD74/TNFSF13B/TGFB1/NCKAP1L/LYN/ZFP36L2/MEF2C/CD300A/THEMIS2/TNFAIP3/TLR4/SASH3/BTK/STAT6/SYK/IL27RA/PTPN6/IL4I1/SAMSN1/BCL6/ZFP36L1/NFAM1/GPR183/SLC39A10/MSH2/PAWR/INPP5D/VAV3/BAD/CDKN1A/RIF1/ID2/TFRC/PKN1/CD320	39
GO:0030330	DNA damage response, signal transduction by p53 class mediator	19/2053	72/18722	0.000204076492373231	0.00174922707748483	CD74/CD44/PLK3/NPM1/PMAIP1/TRIAP1/EEF1E1/USP10/SOX4/SMYD2/GTSE1/BRCA2/SP100/KMT5A/CDKN1A/PLK2/FOXM1/NDRG1/E2F7	19
GO:0033045	regulation of sister chromatid segregation	19/2053	72/18722	0.000204076492373231	0.00174922707748483	DUSP1/CENPF/ZWINT/MAD2L1/CDC6/ANAPC11/RMI2/UBE2C/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	19
GO:1903036	positive regulation of response to wounding	19/2053	72/18722	0.000204076492373231	0.00174922707748483	CXCR4/CLEC7A/FLNA/HMGB1/PRDX2/CD36/GRN/CLDN4/ITGB1/HPSE/HBEGF/KANK1/FERMT1/HRAS/PLPP3/FERMT2/MDK/PTN/PTK2	19
GO:1905818	regulation of chromosome separation	19/2053	72/18722	0.000204076492373231	0.00174922707748483	DUSP1/CENPF/ZWINT/MAD2L1/CDC6/ANAPC11/UBE2C/CDT1/FBXO5/RAD21/BUB3/PLSCR1/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	19
GO:0001655	urogenital system development	59/2053	338/18722	0.000205122291498972	0.00175568295148906	PECAM1/CRIP1/MEF2C/PSAP/LRRK2/VEGFA/FBN1/LRP2/HELLS/SERPINF1/STAT1/MAGED1/CD24/CTSH/MME/RARA/BMP7/LAMA5/CENPF/NOTCH1/IL6R/LGR5/HSPB11/ENPEP/TACSTD2/ADAMTS1/HPGD/AKR1B1/TFAP2A/ADAMTS6/SULF2/NRP1/FRAS1/RHOA/NOTCH2/SOX4/SMARCC1/AHI1/GATA3/DLG5/PBX1/ASS1/COL4A1/LGR4/ID3/C1GALT1/YAP1/CNTRL/ARID5B/DLG1/GLI3/FOXC1/SMAD5/BASP1/PDGFA/PPAT/IRX2/ASXL1/GPC3	59
GO:0000375	RNA splicing, via transesterification reactions	57/2053	324/18722	0.000211461226504864	0.00180736091029798	CELF2/SNRPG/SNRPD1/PABPC1/SNRPB/SNRPF/SRSF2/PSIP1/SNRPE/MBNL3/NPM1/HNRNPR/HNRNPA3/HNRNPA1/HSPA8/LSM2/C1QBP/LSM4/LSM3/SF1/SNRPD3/LSM5/SNRPA1/MAGOHB/PRDX6/LSM7/RBM39/MAGOH/KHSRP/SRSF10/SNU13/PNN/HTATSF1/SRPK1/NCL/HNRNPA2B1/RBM17/MBNL1/DDX1/SRSF7/RBMX/USP39/COIL/TRA2B/SNRNP70/MFAP1/TIA1/SF3A3/PRPF8/LUC7L3/SNRPD2/PRPF19/SNRNP25/SNRNP40/WBP11/LSM8/SRSF4	57
GO:0022904	respiratory electron transport chain	26/2053	114/18722	0.0002123834680377	0.00181266117813115	SCO2/COX6A1/CDK1/NDUFA10/UQCRQ/NDUFB9/NDUFB4/NDUFB7/NDUFA6/NDUFAB1/COX7A2/NDUFV1/CHCHD2/NDUFS8/NDUFV2/COX6C/PARK7/CYC1/UQCR10/NDUFS6/COX5A/UQCRFS1/NDUFC2/NDUFB10/SDHA/NDUFA8	26
GO:0032535	regulation of cellular component size	65/2053	382/18722	0.000212965602011883	0.00181504774441946	TMSB4X/GMFG/CORO1A/MSN/PLEK/NCKAP1L/CAPG/PYCARD/WAS/COTL1/HCK/FN1/TMSB10/SPP1/VEGFA/MYADM/ARPC3/VASP/PREX1/HSP90AB1/ARPC5L/SEMA4A/DSTN/ARHGAP4/NPM1/VAV1/PTK2B/TRPV2/P2RX7/ICAM1/IQGAP2/SEMA6A/RASA1/KANK1/RDX/NRP1/RHOA/ACTR2/LAMTOR4/KANK4/RIN3/GOLGA4/CDK4/TWF2/MYO1C/GRB2/SCIN/SEMA6D/KCNN4/SPTBN1/ARPC4/ACTR3/ARPC1A/WASF2/PFN1/HCLS1/EPS8/EZR/VAV3/DLG1/PPP1R15A/LIMA1/PICALM/TRIOBP/AP2M1	65
GO:0042255	ribosome assembly	17/2053	61/18722	0.000213403188557763	0.00181619734942777	RPS5/RPSA/RPS27/PRKDC/RPLP0/RPS14/RPL5/NPM1/RPL23A/RPS19/C1QBP/RPL3/MRPL20/XRCC5/SBDS/BRIX1/MRTO4	17
GO:0006298	mismatch repair	12/2053	35/18722	0.000217622217844944	0.0018468646493206	HMGB1/PCNA/RPA3/MSH2/LIG1/RPA2/MSH6/RNASEH2A/POLD3/RPA1/ERCC1/EXO1	12
GO:0035633	maintenance of blood-brain barrier	12/2053	35/18722	0.000217622217844944	0.0018468646493206	PECAM1/ACTB/MBP/VEGFA/ITGB1/LAMC1/GJA1/LSR/JAM3/TJP1/VCL/DMD	12
GO:0009394	2'-deoxyribonucleotide metabolic process	13/2053	40/18722	0.000221133802576685	0.00187137209514825	TYMP/SAMHD1/DUT/UPP1/TYMS/DPYD/UNG/DTYMK/NUDT15/PNP/ADK/DCTPP1/DNPH1	13
GO:0030866	cortical actin cytoskeleton organization	13/2053	40/18722	0.000221133802576685	0.00187137209514825	PLEK/LCP1/NCKAP1L/FMNL1/TNF/CALR/ANLN/RHOQ/ECT2/EZR/DLG1/EPB41/RTKN	13
GO:0031098	stress-activated protein kinase signaling cascade	46/2053	247/18722	0.000225267858733073	0.0019036720456316	NCF1/ZFP36/SPI1/LGALS9/CLEC7A/PYCARD/LYN/PAGE4/DUSP1/SCIMP/HMGB1/EGFR/LRRK2/VEGFA/HACD3/TNF/TLR4/DUSP9/IL1B/GSTP1/APP/PTGER4/TLR7/PPIA/GADD45B/ZFP36L1/TREM2/PTK2B/PBK/AKR1B1/HRAS/TRIB1/SPHK1/RHOA/MARVELD3/SIRPA/SDCBP/MYD88/PRDX1/RASSF2/EZR/DLG1/IGF1R/FOXM1/MAP3K4/MAPK14	46
GO:0017038	protein import	40/2053	206/18722	0.000230430483814157	0.00194456104484521	TXNIP/TGFB1/FLNA/JAK2/LRRK2/CDH1/HSPD1/CD36/NFKBIA/HSP90AA1/RAN/SYK/HSP90AB1/CDK1/NOTCH1/RPL23/NUP214/PHB2/HSPA8/FERMT1/CHP1/KPNB1/TOMM40/STAT3/CSE1L/NXT1/PDCD5/TPR/RANBP17/DNAJC19/HCLS1/ECT2/CDKN1A/IPO5/IPO7/GLI3/TRIM28/LMNA/NUP54/MAPK14	40
GO:0016445	somatic diversification of immunoglobulins	18/2053	67/18722	0.000233218350437147	0.0019598180709004	PTPRC/TGFB1/SAMHD1/HSPD1/PRKDC/STAT6/IL27RA/UNG/BCL6/MSH2/MSH6/CTNNBL1/ERCC1/RNF8/RIF1/TFRC/POLQ/EXO1	18
GO:0051306	mitotic sister chromatid separation	18/2053	67/18722	0.000233218350437147	0.0019598180709004	DUSP1/CENPF/ZWINT/MAD2L1/CDC6/ANAPC11/UBE2C/CDT1/FBXO5/RAD21/BUB3/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	18
GO:0070527	platelet aggregation	18/2053	67/18722	0.000233218350437147	0.0019598180709004	PLEK/FLNA/LYN/CD9/FERMT3/FN1/ACTB/JAK2/GNAS/SYK/PTPN6/PPIA/SH2B3/CLIC1/IL6ST/VCL/C1QTNF1/UBASH3B	18
GO:0043112	receptor metabolic process	34/2053	166/18722	0.000234495032000086	0.0019677904783224	FCER1G/LAPTM5/ITGB2/TGFB1/SORL1/CD9/LILRB1/LILRB4/VEGFA/CD36/ARRB2/LRPAP1/SYK/NSG1/ITGB1/RNF43/CXCL8/RIN3/AHI1/SDCBP/GRB2/CD63/FUT8/DTX3L/EZR/TFRC/NUMB/INSR/PICALM/AP2M1/ZNRF3/CAPN1/MYLIP/LDLRAP1	34
GO:0002711	positive regulation of T cell mediated immunity	16/2053	56/18722	0.000237170946629113	0.00198469411405115	HLA-B/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/HLA-F/B2M/HLA-E/HSPD1/IL1B/SASH3/NLRP3/CD1D/RSAD2/GATA3/IL18	16
GO:0043388	positive regulation of DNA binding	16/2053	56/18722	0.000237170946629113	0.00198469411405115	TGFB1/PLAUR/HMGB1/KLF4/JAK2/HMGB2/PARP1/ISL1/CALM2/TXN/GATA3/PARK7/FOXC1/TRIM28/NME1/PPARG	16
GO:0002064	epithelial cell development	42/2053	220/18722	0.000239122888984936	0.00199824141213038	VIM/CXCR4/MSN/PECAM1/FLNA/GPX1/SPINT2/VEGFA/TYMS/TNF/IL1B/MYADM/MET/SOD1/RARA/ADAMTSL4/NOTCH1/KCNQ1/ICAM1/FAT1/AKR1B1/RDX/NOTCH2/RHEB/IL6ST/MYD88/YAP1/TJP1/RAP1A/RAB25/CDK6/KLF5/VCL/EZR/BAD/CDKN1A/PALLD/RILPL2/TFCP2L1/TRIOBP/ASXL1/MYO7A	42
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	38/2053	193/18722	0.000243801688470895	0.00203450644064724	PTPRC/CD74/CD44/NCF1/FCGR1A/CSF1R/PECAM1/CLEC7A/TGFB1/LYN/JAK2/VEGFA/ITGA5/CD4/TNFRSF14/TNF/CD36/ARRB2/CD24/SYK/LILRA5/PARP9/TREM2/IL6R/PTK2B/ICAM1/HBEGF/NRP1/ISL1/HDAC2/IL6ST/EFNA1/HCLS1/ARHGEF2/CSH1/PARP14/YES1/IL18	38
GO:0070391	response to lipoteichoic acid	6/2053	10/18722	0.00024501061414416	0.00203609928651657	CD14/TLR2/TLR4/CD36/TREM2/MAPK14	6
GO:0071223	cellular response to lipoteichoic acid	6/2053	10/18722	0.00024501061414416	0.00203609928651657	CD14/TLR2/TLR4/CD36/TREM2/MAPK14	6
GO:1902946	protein localization to early endosome	6/2053	10/18722	0.00024501061414416	0.00203609928651657	MSN/SORL1/RDX/NRP1/DTX3L/EZR	6
GO:0051924	regulation of calcium ion transport	47/2053	255/18722	0.000248321204725411	0.00205512348528062	TSPO/CXCR4/CORO1A/CCL3/CYBA/CCL4/CD84/LYN/LILRB2/SLC8A1/LILRB1/CD4/CCR1/HOMER3/ARRB2/CXCL10/LILRA2/PTPN6/LILRA5/LGALS3/ATP2B1/PTK2B/IL16/TRPV2/P2RX7/ICAM1/CD33/VMP1/TSPAN13/GJA1/CAMK2D/KCNE3/GNAI2/RHOA/CALM2/C4orf3/VDAC1/YWHAE/SLC9A1/CAMK2G/BEST1/DMD/FKBP1A/UBASH3B/PACSIN3/EPB41/HOMER1	47
GO:1903362	regulation of cellular protein catabolic process	47/2053	255/18722	0.000248321204725411	0.00205512348528062	LAPTM5/MSN/GPX1/LRRK2/LRP2/TNFAIP3/RPS7/PLK3/HSP90AA1/HSP90AB1/RPL5/TREM2/RPL23/PTK2B/PSME2/HAMP/PSMC3/UBB/PBK/TRIB1/RDX/PSMC1/NUDT15/SMARCC1/PSMD14/SDCBP/ATRAID/EFNA1/BAG2/USP14/SVIP/PITHD1/PSMC2/MAGEF1/TMTC3/PARK7/EZR/COMMD1/RAD23B/HSPA1A/CDK2/VCP/PLK2/GABARAP/PTK2/MYLIP/ALAD	47
GO:0010466	negative regulation of peptidase activity	48/2053	262/18722	0.000248327421138075	0.00205512348528062	TIMP1/SERPINA1/BST2/CD44/PLAUR/SORL1/CST3/ITIH5/SPINT1/GPX1/KLF4/SPINT2/VEGFA/IFI16/PEBP1/TNF/SERPINF1/APP/ARRB2/C3/PRDX5/CARD16/APLP2/TIMP2/IFI6/TIMP3/CRIM1/CST6/NR4A1/DHCR24/SERPINH1/NAIP/CSTB/BIRC5/BIRC3/TRIAP1/SIAH2/RPS6KA1/PRDX3/BCL2L12/CSTA/USP14/PARK7/SERPINB8/PICALM/SERPING1/GAPDH/GPC3	48
GO:0002407	dendritic cell chemotaxis	10/2053	26/18722	0.000248960429412909	0.00205752421002404	CXCR4/SPI1/LGALS9/HMGB1/CCR1/CCR2/CALR/GPR183/C1QBP/TRPM2	10
GO:1903034	regulation of response to wounding	34/2053	167/18722	0.00026397790107003	0.0021756325091544	CXCR4/CLEC7A/FLNA/CD9/HMGB1/KLF4/SPP1/ALOX5/PRDX2/TNF/TNFAIP3/CD36/GRN/CLDN4/ITGB1/SIGLEC10/HPSE/SH2B3/GJA1/HBEGF/KANK1/FERMT1/HRAS/TNFRSF12A/PLPP3/PTPRF/FERMT2/C1QTNF1/MDK/UBASH3B/PTN/PTK2/PDGFA/SERPING1	34
GO:0002260	lymphocyte homeostasis	17/2053	62/18722	0.000264339349862259	0.0021756325091544	CD74/CORO1A/TNFSF13B/TSC22D3/LGALS9/NCKAP1L/LYN/MEF2C/SKIL/DOCK10/TNFAIP3/GAPT/PMAIP1/RPS6/TCIRG1/DOCK11/PKN1	17
GO:0009116	nucleoside metabolic process	17/2053	62/18722	0.000264339349862259	0.0021756325091544	APOBEC3A/TYMP/UPP1/DPYD/CDA/DTYMK/TK1/APOBEC3G/APOBEC3C/MTAP/UMPS/PNP/ERH/NME4/ADK/DNPH1/PPAT	17
GO:0072594	establishment of protein localization to organelle	70/2053	422/18722	0.000269423168117316	0.00221443699822451	LAPTM5/TXNIP/TSPO/CD68/TGFB1/FLNA/SORL1/IL10RA/RAC2/JAK2/LRRK2/CDH1/TNFAIP3/LMAN1/HSPD1/CD36/NFKBIA/HSP90AA1/RAN/SYK/HSP90AB1/CDK1/NOTCH1/RPL23/HSPA5/NUP214/HK2/BNIP3L/PHB2/HSPA8/TIMM13/FERMT1/CHP1/SPCS2/KPNB1/TOMM40/STAT3/CSE1L/TCP1/NXT1/CCT6A/PDCD5/BRCA2/TOMM34/TPR/CCT2/RANBP17/SEC63/DNAJC19/VPS13C/SAE1/FIS1/HCLS1/ECT2/NMT1/CDKN1A/IPO5/IPO7/SGTB/CCT4/GLI3/PMPCB/VPS25/TRIM28/CCT8/LMNA/NUP54/HUWE1/NDUFA13/MAPK14	70
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	56/2053	320/18722	0.000274646428481398	0.00225120023345408	CELF2/SNRPG/SNRPD1/PABPC1/SNRPB/SNRPF/SRSF2/PSIP1/SNRPE/MBNL3/NPM1/HNRNPR/HNRNPA3/HNRNPA1/HSPA8/LSM2/C1QBP/LSM4/LSM3/SF1/SNRPD3/LSM5/SNRPA1/MAGOHB/PRDX6/LSM7/RBM39/MAGOH/SRSF10/SNU13/PNN/HTATSF1/SRPK1/NCL/HNRNPA2B1/RBM17/MBNL1/DDX1/SRSF7/RBMX/USP39/COIL/TRA2B/SNRNP70/MFAP1/TIA1/SF3A3/PRPF8/LUC7L3/SNRPD2/PRPF19/SNRNP25/SNRNP40/WBP11/LSM8/SRSF4	56
GO:0000398	mRNA splicing, via spliceosome	56/2053	320/18722	0.000274646428481398	0.00225120023345408	CELF2/SNRPG/SNRPD1/PABPC1/SNRPB/SNRPF/SRSF2/PSIP1/SNRPE/MBNL3/NPM1/HNRNPR/HNRNPA3/HNRNPA1/HSPA8/LSM2/C1QBP/LSM4/LSM3/SF1/SNRPD3/LSM5/SNRPA1/MAGOHB/PRDX6/LSM7/RBM39/MAGOH/SRSF10/SNU13/PNN/HTATSF1/SRPK1/NCL/HNRNPA2B1/RBM17/MBNL1/DDX1/SRSF7/RBMX/USP39/COIL/TRA2B/SNRNP70/MFAP1/TIA1/SF3A3/PRPF8/LUC7L3/SNRPD2/PRPF19/SNRNP25/SNRNP40/WBP11/LSM8/SRSF4	56
GO:0001659	temperature homeostasis	35/2053	174/18722	0.000275433139613715	0.00225149705406307	CXCR4/PLAC8/GPX1/UCP2/JAK2/VEGFA/TNF/TLR4/IL1B/CD36/G0S2/CEBPB/GNAS/CCR2/STAT6/SYK/NOTCH1/TRPV2/ID1/ACADVL/GJA1/ALDH1A1/EPAS1/TRPM2/ADRB1/FABP5/STAT3/RHEB/HADH/FH/LGR4/IGF1R/PTGES/KDM6B/IL18	35
GO:0007584	response to nutrient	35/2053	174/18722	0.000275433139613715	0.00225149705406307	TSPO/CYBB/SLC8A1/EGFR/SOD2/SPP1/TYMS/GSTP1/STAT1/HMOX1/KYNU/CXCL10/AGL/RARA/BMP7/SRSF2/ATP2B1/HAMP/CCND1/GNAI2/HAT1/SLC6A4/LDHA/VDR/ACSL4/SLC16A1/FOLR1/GCLM/ASS1/TRIM24/ERCC1/ENSA/PTN/PPARG/ALAD	35
GO:0002828	regulation of type 2 immune response	11/2053	31/18722	0.000281570695676995	0.00229229874363904	CD74/CD86/CCR2/STAT6/NLRP3/IL27RA/RARA/RSAD2/BCL6/GATA3/IL18	11
GO:0033006	regulation of mast cell activation involved in immune response	11/2053	31/18722	0.000281570695676995	0.00229229874363904	LGALS9/CD84/LYN/CD300A/RAC2/FGR/HMOX1/STXBP2/ADGRE2/SYK/SNX4	11
GO:0045066	regulatory T cell differentiation	11/2053	31/18722	0.000281570695676995	0.00229229874363904	HLA-DRA/HLA-DRB1/LGALS9/LILRB2/LILRB4/CD46/IL4I1/BCL6/IRF1/MDK/FANCA	11
GO:0036294	cellular response to decreased oxygen levels	33/2053	161/18722	0.000283416413949455	0.00230419848739394	CYBB/SLC8A1/VEGFA/P4HB/HMOX1/NAMPT/PLK3/CARD16/MALAT1/BMP7/NOTCH1/ZFP36L1/TREM2/ADAM8/ICAM1/HILPDA/SLC29A1/BNIP3L/PHB2/KCNMB1/PMAIP1/EPAS1/CCNA2/RGCC/CHCHD2/BACH1/SLC9A1/BAD/BNIP3/PTN/LMNA/E2F1/NDRG1	33
GO:1990748	cellular detoxification	26/2053	116/18722	0.00028481112945822	0.00230832627909669	GPX1/SOD2/ALOX5AP/MGST3/PRDX2/CD36/GSTP1/PRDX4/GLRX/PRDX5/SOD1/BMP7/S100A9/DHFR/GPX8/ADH5/ALDH1A1/TXN/PRDX3/PRDX6/PRDX1/MGST1/SOD3/PARK7/GCH1/PTGES	26
GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	18/2053	68/18722	0.000285078295468441	0.00230832627909669	HLA-DRA/HLA-DRB1/LGALS9/CD86/HMGB1/PTGER4/STAT6/NLRP3/RARA/SEMA4A/BCL6/IL6R/GPR183/SPN/STAT3/GATA3/NFKBIZ/IL18	18
GO:0042267	natural killer cell mediated cytotoxicity	18/2053	68/18722	0.000285078295468441	0.00230832627909669	HLA-B/HLA-A/CORO1A/HLA-F/LGALS9/HLA-E/HAVCR2/LILRB1/TUBB/SLAMF7/ARRB2/CADM1/PTPN6/LYST/TUBB4B/VAV1/PRDX1/IL18	18
GO:0014074	response to purine-containing compound	31/2053	148/18722	0.00028673247580046	0.00231859144852124	SLC8A1/DUSP1/FOS/HSP90B1/CASP1/AQP9/HSPD1/APP/STAT1/PTAFR/BSG/SOD1/ZFP36L1/KCNQ1/PTK2B/HSPA5/P2RX7/FOSB/CDO1/TRPM2/SLC6A4/LDHA/HDAC2/ASS1/RAP1A/P2RY11/JUN/APEX1/EZR/NME1/AKAP9	31
GO:0030224	monocyte differentiation	12/2053	36/18722	0.000294116380731736	0.00237190629622367	HLA-DRB1/CD74/CSF1R/VEGFA/CD4/IFI16/IRF7/ZFP36L1/CDK6/JUN/INPP5D/PPARG	12
GO:0071402	cellular response to lipoprotein particle stimulus	12/2053	36/18722	0.000294116380731736	0.00237190629622367	FCER1G/CD68/ITGB2/CD9/TLR4/CD36/TLR6/SYK/ITGB1/TREM2/MYD88/PPARG	12
GO:0032069	regulation of nuclease activity	9/2053	22/18722	0.000295238310885087	0.00237457086502751	OAS2/HMGB1/PCNA/OASL/HMGB2/RPS3/NPM1/OAS1/HSPA1A	9
GO:0032727	positive regulation of interferon-alpha production	9/2053	22/18722	0.000295238310885087	0.00237457086502751	HMGB1/TLR4/HSPD1/STAT1/IRF7/TLR7/IRF5/TLR8/DDX58	9
GO:0061756	leukocyte adhesion to vascular endothelial cell	16/2053	57/18722	0.000296546283564854	0.00238189785995867	ITGB2/KLF4/ALOX5/TNF/ITGA4/PTAFR/CCR2/SELPLG/ITGB1/SPN/ICAM1/CX3CR1/RHOA/SELL/MDK/NFAT5	16
GO:0019722	calcium-mediated signaling	39/2053	202/18722	0.000309176992241301	0.00248002934952915	PTPRC/CXCR4/CCL3/PLEK/CCL4/CLEC7A/LAT2/SLC8A1/EGFR/LRRK2/CD4/CCR1/TNF/HOMER3/GBP1/CCR2/BTK/SYK/CCRL2/MCTP1/TREM2/PTK2B/P2RX7/CX3CR1/CAMK2D/CXCL8/CHP1/TRPM2/SPHK1/CALM2/CIB1/P2RY11/FIS1/NUDT4/SLC9A1/FHL2/DMD/DEFB1/NFAT5	39
GO:0034103	regulation of tissue remodeling	21/2053	86/18722	0.000312914836482088	0.0025033186918567	CSF1R/TGFB1/CST3/EGFR/SPP1/TNFAIP3/RUNX1/GPNMB/SYK/CSK/ADAM8/PDK4/HAMP/P2RX7/SYT7/INPP5D/TFRC/MDK/UBASH3B/IL18/SUCO	21
GO:2001251	negative regulation of chromosome organization	21/2053	86/18722	0.000312914836482088	0.0025033186918567	DUSP1/PARP1/TOP2A/CENPF/ZWINT/MAD2L1/HNRNPA1/CDT1/MCM2/FBXO5/RAD21/BUB3/TPR/RAD50/NDC80/TTK/ERCC1/AURKB/LCMT1/BUB1B/KNTC1	21
GO:0071236	cellular response to antibiotic	7/2053	14/18722	0.000321954852033361	0.0025722092039949	CRIP1/MEF2C/RPL23/HSPA5/EZH2/ACTR2/SLC9A1	7
GO:0050854	regulation of antigen receptor-mediated signaling pathway	17/2053	63/18722	0.000325501671292204	0.00259708780286333	LAPTM5/PTPRC/LYN/CD300A/LILRB4/GBP1/RPS3/PTPN6/LGALS3/NFAM1/SLC39A10/CMTM3/PRKCB/PAWR/KCNN4/PHPT1/EZR	17
GO:0030889	negative regulation of B cell proliferation	8/2053	18/18722	0.000327461191867287	0.00260579197772377	TYROBP/MNDA/LYN/CD300A/BTK/PAWR/INPP5D/PKN1	8
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	8/2053	18/18722	0.000327461191867287	0.00260579197772377	HLA-B/HLA-A/HLA-F/LGALS9/HLA-E/HAVCR2/LILRB1/ARRB2	8
GO:0031103	axon regeneration	15/2053	52/18722	0.000328346239453255	0.00260801706486827	TSPO/FLNA/KLF4/SPP1/JAK2/GRN/DAG1/NREP/DHFR/ISL1/FOLR1/JAM3/PTPRF/PTN/MTR	15
GO:0051225	spindle assembly	26/2053	117/18722	0.000328610150173402	0.00260801706486827	FLNA/TUBB/RPS3/PRC1/SMC3/ASPM/KPNB1/RHOA/KIF23/FBXO5/TPX2/MYBL2/TPR/HAUS8/STAG1/HAUS1/HSPA1A/AURKB/CHMP4C/GPSM2/KIF4A/DRG1/CCDC69/SAC3D1/KIF11/KIFC1	26
GO:0032386	regulation of intracellular transport	58/2053	337/18722	0.000336757740319898	0.00266914985722508	ITGB2/MSN/LCP1/TGFB1/FLNA/SORL1/RAC2/JAK2/LRRK2/ITGAM/TCAF1/MX2/CDH1/OAZ1/LMAN1/IL1B/CD36/PLK3/RAN/HSP90AB1/CAMK1/CDK1/NUP214/IFI27/BNIP3L/FERMT1/HRAS/CHP1/RDX/BARD1/CIB1/PTPN14/TXN/PDCD5/MYO1C/ANK3/KIF20B/TMEM30B/TPR/SVIP/SP100/SAE1/FIS1/YWHAE/HCLS1/PARK7/ECT2/EZR/NMT1/IPO5/GLI3/TRIM28/B3GAT3/NUP54/CTDSPL2/HUWE1/MAPK14/LDLRAP1	58
GO:0006913	nucleocytoplasmic transport	53/2053	301/18722	0.000338450534572224	0.00267549829701363	TXNIP/TGFB1/FLNA/JAK2/LRRK2/MX2/CDH1/IL1B/CD36/NFKBIA/RAN/SYK/HSP90AB1/CAMK1/CDK1/NOTCH1/HHEX/CALR/RPL23/NPM1/HNRNPA1/NUP214/IFI27/PHB2/FERMT1/CHP1/KPNB1/BARD1/PTPN14/STAT3/CSE1L/TXN/UPF3A/NXT1/TPR/RANBP17/SP100/YWHAE/HNRNPA2B1/HCLS1/PARK7/ECT2/CDKN1A/IPO5/IPO7/GLI3/PABPN1/TRIM28/LMNA/NUP54/CTDSPL2/HSPA9/MAPK14	53
GO:0051169	nuclear transport	53/2053	301/18722	0.000338450534572224	0.00267549829701363	TXNIP/TGFB1/FLNA/JAK2/LRRK2/MX2/CDH1/IL1B/CD36/NFKBIA/RAN/SYK/HSP90AB1/CAMK1/CDK1/NOTCH1/HHEX/CALR/RPL23/NPM1/HNRNPA1/NUP214/IFI27/PHB2/FERMT1/CHP1/KPNB1/BARD1/PTPN14/STAT3/CSE1L/TXN/UPF3A/NXT1/TPR/RANBP17/SP100/YWHAE/HNRNPA2B1/HCLS1/PARK7/ECT2/CDKN1A/IPO5/IPO7/GLI3/PABPN1/TRIM28/LMNA/NUP54/CTDSPL2/HSPA9/MAPK14	53
GO:0002287	alpha-beta T cell activation involved in immune response	18/2053	69/18722	0.000346681556715362	0.0027333631278478	HLA-DRA/HLA-DRB1/LGALS9/CD86/HMGB1/PTGER4/STAT6/NLRP3/RARA/SEMA4A/BCL6/IL6R/GPR183/SPN/STAT3/GATA3/NFKBIZ/IL18	18
GO:0002293	alpha-beta T cell differentiation involved in immune response	18/2053	69/18722	0.000346681556715362	0.0027333631278478	HLA-DRA/HLA-DRB1/LGALS9/CD86/HMGB1/PTGER4/STAT6/NLRP3/RARA/SEMA4A/BCL6/IL6R/GPR183/SPN/STAT3/GATA3/NFKBIZ/IL18	18
GO:0032703	negative regulation of interleukin-2 production	10/2053	27/18722	0.000356779642892667	0.00280928852671391	LAPTM5/PTPRC/ZFP36/HAVCR2/LILRB4/TNFAIP3/HOMER3/GBP1/GATA3/EZR	10
GO:0097237	cellular response to toxic substance	27/2053	124/18722	0.00036061866762136	0.00283579555141305	GPX1/SOD2/ALOX5AP/MGST3/PRDX2/CD36/GSTP1/PRDX4/GLRX/PRDX5/SOD1/BMP7/S100A9/DHFR/GPX8/ADH5/ALDH1A1/TXN/PRDX3/PRDX6/PRDX1/MGST1/SOD3/FIS1/PARK7/GCH1/PTGES	27
GO:0030838	positive regulation of actin filament polymerization	23/2053	99/18722	0.000362006021667853	0.002842979227758	GMFG/CORO1A/NCKAP1L/PYCARD/WAS/HCK/ARPC3/VASP/ARPC5L/PTK2B/ICAM1/IQGAP2/RHOA/ACTR2/MYO1C/GRB2/SCIN/ARPC4/ACTR3/ARPC1A/WASF2/PFN1/DLG1	23
GO:0051591	response to cAMP	22/2053	93/18722	0.000368105761004507	0.00288497167038683	SLC8A1/DUSP1/FOS/AQP9/APP/STAT1/PTAFR/BSG/ZFP36L1/KCNQ1/PTK2B/HSPA5/FOSB/CDO1/LDHA/ASS1/RAP1A/JUN/APEX1/EZR/NME1/AKAP9	22
GO:0010833	telomere maintenance via telomere lengthening	20/2053	81/18722	0.000368314716586052	0.00288497167038683	PARP1/HSP90AA1/HSP90AB1/PKIB/RAD51/HNRNPA1/NHP2/RFC1/TCP1/CCT6A/CCT2/XRCC5/RAD50/PNKP/RPA1/HNRNPA2B1/CCT4/AURKB/CCT8/MAP3K4	20
GO:0022612	gland morphogenesis	26/2053	118/18722	0.000378242506689131	0.00295887228179242	MSN/CSF1R/TGFB1/CRIP1/TNF/TNFAIP3/CEBPB/TGM2/STAT6/DAG1/BMP7/LAMA5/NOTCH1/PHB2/SULF2/NRP1/RPS6KA1/NOTCH2/VDR/LRP5/GLI3/MDK/PTN/TBX3/PDGFA/CAPN1	26
GO:0019692	deoxyribose phosphate metabolic process	13/2053	42/18722	0.000380314578395788	0.00296734391466154	TYMP/SAMHD1/DUT/UPP1/TYMS/DPYD/UNG/DTYMK/NUDT15/PNP/ADK/DCTPP1/DNPH1	13
GO:0033003	regulation of mast cell activation	13/2053	42/18722	0.000380314578395788	0.00296734391466154	LGALS9/CD84/LYN/CD300A/RAC2/FGR/HMOX1/CD300LF/STXBP2/ADGRE2/SYK/SNX4/PLSCR1	13
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	11/2053	32/18722	0.000386865262451101	0.00301453451260598	HLA-DRA/HLA-DRB1/LGALS9/NCKAP1L/CD86/CD83/SASH3/NLRP3/RARA/NFKBIZ/IL18	11
GO:0002369	T cell cytokine production	12/2053	37/18722	0.000392236539749233	0.00303793231893652	HLA-A/HLA-F/TNFRSF1B/B2M/LILRB4/IL1B/CCR2/SASH3/NLRP3/RSAD2/GATA3/IL18	12
GO:0002724	regulation of T cell cytokine production	12/2053	37/18722	0.000392236539749233	0.00303793231893652	HLA-A/HLA-F/TNFRSF1B/B2M/LILRB4/IL1B/CCR2/SASH3/NLRP3/RSAD2/GATA3/IL18	12
GO:0032570	response to progesterone	12/2053	37/18722	0.000392236539749233	0.00303793231893652	TXNIP/TSPO/TGFB1/TLR2/FOS/TYMS/CLDN4/FOSB/YAP1/ABHD2/BAD/PTN	12
GO:1904358	positive regulation of telomere maintenance via telomere lengthening	12/2053	37/18722	0.000392236539749233	0.00303793231893652	PKIB/HNRNPA1/TCP1/CCT6A/CCT2/XRCC5/PNKP/HNRNPA2B1/CCT4/AURKB/CCT8/MAP3K4	12
GO:0010821	regulation of mitochondrion organization	30/2053	144/18722	0.000392399591195967	0.00303793231893652	TSPO/TNFSF10/PYCARD/PLAUR/GPX1/LRRK2/ARRB2/SLC25A5/TREM2/BNIP3L/PMAIP1/STAT2/TRIAP1/SLC25A4/PDCD5/VDAC1/CHCHD10/VPS13C/INF2/FIS1/PARK7/HSPA1A/BAD/NMT1/BNIP3/PISD/TFRC/LMNA/HUWE1/PPARG	30
GO:0009141	nucleoside triphosphate metabolic process	25/2053	112/18722	0.000394748420893815	0.00304825035439239	TMSB4X/TGFB1/SAMHD1/DUT/GIMAP7/LRRK2/TYMS/PARP1/RAN/TREM2/DTYMK/ALDOA/RHOA/STAT3/NUDT15/STOML2/NME4/ADK/IMPDH2/RHOQ/DCTPP1/SMPDL3A/VCP/NME1/PRKAG2	25
GO:0043406	positive regulation of MAP kinase activity	25/2053	112/18722	0.000394748420893815	0.00304825035439239	TGFB1/S100A12/EGFR/LRRK2/VEGFA/TNF/TLR4/IL1B/FGD2/MAGED1/RPS3/CD24/TLR6/SYK/CSK/ADAM8/PTK2B/PIK3R5/ERP29/FLT1/EZH2/HRAS/INSR/MAP3K4/PDGFA	25
GO:0045670	regulation of osteoclast differentiation	17/2053	64/18722	0.000398539472860998	0.00307356919944215	TYROBP/CCL3/MAFB/LILRB1/LILRB3/LILRB4/FOS/FBN1/CCR1/TNF/TLR4/CEBPB/TREM2/NOTCH2/RASSF2/INPP5D/UBASH3B	17
GO:0050821	protein stabilization	37/2053	191/18722	0.000406462487370881	0.00313064816973721	TYROBP/IFI30/FLNA/HSPD1/GRN/RPS7/HSP90AA1/HSP90AB1/RPL5/PPIB/CALR/RPL23/NPM1/PHB2/AAK1/CHP1/SOX4/TCP1/USP27X/CCT6A/MFSD1/PLPP3/CCT2/EFNA1/BAG2/PHB/PFN1/RASSF2/PARK7/HSPA1A/TBL1X/CCT4/STK4/P3H1/CCT8/CTNND1/GAPDH	37
GO:0002707	negative regulation of lymphocyte mediated immunity	15/2053	53/18722	0.000412070084731824	0.00316976988255249	HLA-B/HLA-A/PTPRC/HLA-F/LGALS9/NCKAP1L/HLA-E/HAVCR2/LILRB1/LILRB4/ARRB2/CD46/PTPN6/IL4I1/BCL6	15
GO:1904375	regulation of protein localization to cell periphery	27/2053	125/18722	0.000412739654323703	0.00317085521887608	TGFB1/ACTB/ABI3/EGFR/TNF/GBP1/DAG1/CSK/ITGB1/LGALS3/TREM2/HRAS/CIB1/SPTBN1/RAP1A/GOPC/GNAI1/RHOG/RHOQ/EZR/DLG1/NUMB/PICALM/GPSM2/AP2M1/EPB41/LDLRAP1	27
GO:0010959	regulation of metal ion transport	67/2053	406/18722	0.000417057957494866	0.00319993317770997	TSPO/FXYD5/CXCR4/CORO1A/CCL3/CYBA/CCL4/CD84/FLNA/LYN/LILRB2/B2M/SLC8A1/LILRB1/CD4/CCR1/HOMER3/FXYD3/ARRB2/CXCL10/LILRA2/GLRX/PTPN6/LILRA5/ITGB1/LGALS3/KCNAB2/ATP2B1/TREM2/KCNQ1/PTK2B/IL16/HAMP/TRPV2/P2RX7/ICAM1/CD33/VMP1/TSPAN13/GJA1/CAMK2D/KCNMB1/KCNE3/GNAI2/CHP1/RHOA/CALM2/C4orf3/ANK3/CD63/KCNN4/VDAC1/YWHAE/SLC9A1/CAMK2G/BEST1/COMMD1/DLG1/DMD/FKBP1A/PTPN3/UBASH3B/AKAP9/PACSIN3/EPB41/HOMER1/ACTN4	67
GO:0015980	energy derivation by oxidation of organic compounds	55/2053	318/18722	0.000417840125125958	0.00320184003927937	HMGB1/PHLDA2/AGL/SCO2/COX6A1/CDK1/ACADVL/IDH2/MSH2/NDUFA10/UQCRQ/NDUFB9/UQCC2/CISD1/RHOA/NDUFB4/NDUFB7/NDUFA6/IL6ST/ARL2/NDUFAB1/FH/DHTKD1/PDHA1/COX7A2/NDUFV1/STOML2/MDH1/CHCHD10/CHCHD2/IDH1/NDUFS8/NDUFV2/COX6C/PARK7/CYC1/UQCR10/UQCRC2/UGP2/NDUFS6/SUCLG1/GAA/BNIP3/COX5A/INSR/VCP/PHKB/TRAP1/UQCRFS1/GFPT1/NDUFC2/NDUFB10/SDHA/PRKAG2/NDUFA8	55
GO:0050708	regulation of protein secretion	48/2053	268/18722	0.000424569273518533	0.00324925464427449	HLA-DRB1/TGFB1/TLR2/EGFR/UCP2/JAK2/ALOX5/TNF/TLR4/IL1B/MYH10/WLS/GLUL/MPC2/SERP1/PPIA/DPP4/RSAD2/TREM2/ADAM8/CD33/RHBDF2/ERP29/IDH2/GJA1/HMGN3/UQCC2/TRPM2/KLF7/ISL1/SYT7/FRMD4A/SOX4/HADH/ACSL4/SLC16A1/LRP5/KCNN4/PHPT1/EZR/BAD/TCIRG1/MIDN/DNAJC1/CD2AP/ENSA/P3H1/TM7SF3	48
GO:0006469	negative regulation of protein kinase activity	40/2053	212/18722	0.000425638416592535	0.00325328726057988	PTPRC/PYCARD/LYN/SORL1/SLC8A1/CD300A/LILRB4/DUSP1/TNFAIP3/IRAK3/IL1B/GSTP1/PTPN6/BMP7/PKIB/PPIA/HHEX/GADD45B/NR2F2/NPM1/SH2B3/CDKN1C/TRIB1/CHP1/LRP5/CDKN2A/RGS2/PARK7/CORO1C/MVP/CDKN1A/IPO5/IPO7/VPS25/UBASH3B/MLLT1/PKN1/PRKAG2/PPARG/NCAPG2	40
GO:0006839	mitochondrial transport	46/2053	254/18722	0.000430454356426427	0.00328407613361481	TSPO/RAC2/UCP2/LRRK2/LMAN1/HSPD1/SLC25A37/HSP90AA1/MPC2/SLC25A5/SLC25A3/HK2/BNIP3L/TIMM13/PMAIP1/SLC25A1/TOMM40/SLC25A36/STAT3/SFXN3/SLC25A4/PDCD5/SFXN1/TOMM34/VDAC1/HEBP2/STOML2/CHCHD10/AFG3L2/DNAJC19/SAE1/FIS1/SLC9A1/MCUR1/HSPA1A/BAD/NMT1/BNIP3/PMPCB/MRS2/MTX2/HUWE1/NDUFA13/MPC1/SLC25A6/DYNLT1	46
GO:0009266	response to temperature stimulus	35/2053	178/18722	0.00043076131952581	0.00328407613361481	CD14/CXCR4/LYN/PLAC8/FOS/TFEC/UCP2/SOD2/METRNL/HSPD1/HMOX1/ARRB2/NR2F6/CXCL10/RBBP7/NFKBIA/HSP90AA1/HSP90AB1/SOD1/PSIP1/ATP2B1/TRPV2/ACADVL/HSPA6/TRPM2/ADRB1/HDAC2/TPR/EIF2AK4/YWHAE/SLC9A1/HSPA1A/HSBP1L1/CDKN1A/VCP	35
GO:0019430	removal of superoxide radicals	9/2053	23/18722	0.000438076386713598	0.00333560700543349	SOD2/PRDX2/CD36/SOD1/BMP7/DHFR/PRDX1/SOD3/GCH1	9
GO:0006753	nucleoside phosphate metabolic process	79/2053	497/18722	0.000443637010802407	0.0033706540755355	TMSB4X/TYMP/TGFB1/SAMHD1/DUT/UPP1/GIMAP7/LRRK2/TYMS/HINT1/FBP1/PARP1/APP/RRM1/NAMPT/KYNU/DPYD/SLC26A2/RAN/MPC2/ACSS1/TECR/UNG/QPRT/PARP9/TREM2/HK3/CDA/PDK4/PAICS/DTYMK/ENTPD1/P2RX7/PDE4A/RRM2/TK1/HK2/DDIT4/IDH2/PPT1/SLC2A6/SULT1A1/NUDT8/ALDOA/SLC25A1/LDHA/RHOA/UMPS/STAT3/NUDT15/PNP/ARL2/ACSL4/GMPS/DHTKD1/TPST2/PMVK/PDHA1/STOML2/NME4/ADK/NUDT4/IMPDH2/NUDT5/RHOQ/PARK7/DLG1/BAD/DCTPP1/MPP1/AMPD3/SMPDL3A/INSR/VCP/NME1/DNPH1/PPAT/GAPDH/PRKAG2	79
GO:0043524	negative regulation of neuron apoptotic process	30/2053	145/18722	0.000443802786612174	0.0033706540755355	CORO1A/C5AR1/MEF2C/SOD2/JAK2/NR4A2/HSPD1/HMOX1/CEBPB/GRN/ARRB2/HSP90AB1/SOD1/ADAM8/PTK2B/NAIP/RASA1/PPT1/BTG2/SET/CX3CR1/MSH2/HRAS/NRP1/ISL1/RHOA/GCLM/PARK7/MDK/XRCC2	30
GO:0010569	regulation of double-strand break repair via homologous recombination	14/2053	48/18722	0.000454231269150682	0.00343954738866564	WAS/PARP1/FUS/RAD51AP1/RAD51/RMI2/CHEK1/RPA2/ACTR2/MAGEF1/TIMELESS/RIF1/POLQ/FIGNL1	14
GO:0043303	mast cell degranulation	14/2053	48/18722	0.000454231269150682	0.00343954738866564	LGALS9/CD84/LYN/LAT2/CD300A/RAC2/FGR/HMOX1/STXBP2/ADGRE2/BTK/SYK/SNX4/S100A13	14
GO:0001836	release of cytochrome c from mitochondria	16/2053	59/18722	0.000454593513201975	0.00343954738866564	TNFSF10/PYCARD/PLAUR/GPX1/SOD2/GGCT/ARRB2/IFI6/PMAIP1/TRIAP1/PDCD5/FIS1/JUN/BAD/BNIP3/LMNA	16
GO:0000018	regulation of DNA recombination	24/2053	107/18722	0.000474041730944607	0.00358217932703733	PTPRC/TGFB1/WAS/PARP1/FUS/STAT6/IL27RA/RAD51AP1/BCL6/RAD51/RMI2/MSH2/CHEK1/RPA2/MSH6/ACTR2/BLM/RAD50/MAGEF1/TIMELESS/RIF1/TFRC/POLQ/FIGNL1	24
GO:0048524	positive regulation of viral process	17/2053	65/18722	0.00048529649131074	0.00365801375359854	HLA-DRB1/LGALS1/CD74/LGALS9/CD4/IFIT1/HACD3/P4HB/PABPC1/TOP2A/PPIA/NOTCH1/DDB1/STAU1/TRIM38/SRPK1/TOP2B	17
GO:0090307	mitotic spindle assembly	17/2053	65/18722	0.00048529649131074	0.00365801375359854	FLNA/PRC1/SMC3/KPNB1/RHOA/KIF23/TPX2/MYBL2/TPR/STAG1/HSPA1A/AURKB/CHMP4C/KIF4A/DRG1/KIF11/KIFC1	17
GO:0071888	macrophage apoptotic process	6/2053	11/18722	0.000488930311402737	0.00368078026150116	MEF2C/CTSL/IRF7/PLEKHO2/TCP1/CDKN2A	6
GO:0014002	astrocyte development	13/2053	43/18722	0.00049096837461897	0.00368226280964227	VIM/S100A8/C5AR1/EGFR/TNF/TLR4/APP/GRN/S100A9/TREM2/C1QA/CDK6/IFNGR1	13
GO:0034142	toll-like receptor 4 signaling pathway	13/2053	43/18722	0.00049096837461897	0.00368226280964227	CD14/LYN/LY96/PIK3AP1/SCIMP/HMGB1/TNFAIP3/TLR4/LILRA2/NFKBIA/TREM2/OAS1/IFI35	13
GO:0042088	T-helper 1 type immune response	13/2053	43/18722	0.00049096837461897	0.00368226280964227	HLA-DRB1/SLC11A1/HAVCR2/HMGB1/TLR4/IL1B/CCR2/STAT6/IL27RA/SEMA4A/SPN/HRAS/IL18	13
GO:0000303	response to superoxide	10/2053	28/18722	0.000500834647669204	0.00372367767783795	UCP2/SOD2/PRDX2/CD36/SOD1/BMP7/DHFR/PRDX1/SOD3/GCH1	10
GO:0002313	mature B cell differentiation involved in immune response	10/2053	28/18722	0.000500834647669204	0.00372367767783795	LGALS1/SPI1/DOCK10/IRF8/LFNG/PTK2B/GPR183/MFNG/NOTCH2/DOCK11	10
GO:0002507	tolerance induction	10/2053	28/18722	0.000500834647669204	0.00372367767783795	HLA-B/LGALS9/LYN/LILRB2/HLA-E/HAVCR2/LILRB4/HMGB1/TNFAIP3/IRAK3	10
GO:0010575	positive regulation of vascular endothelial growth factor production	10/2053	28/18722	0.000500834647669204	0.00372367767783795	TGFB1/C5AR1/C3AR1/IL1B/C3/HPSE/BRCA1/SULF2/ISL1/IL6ST	10
GO:0032607	interferon-alpha production	10/2053	28/18722	0.000500834647669204	0.00372367767783795	HAVCR2/HMGB1/TLR4/HSPD1/STAT1/IRF7/TLR7/IRF5/TLR8/DDX58	10
GO:0032647	regulation of interferon-alpha production	10/2053	28/18722	0.000500834647669204	0.00372367767783795	HAVCR2/HMGB1/TLR4/HSPD1/STAT1/IRF7/TLR7/IRF5/TLR8/DDX58	10
GO:1902624	positive regulation of neutrophil migration	10/2053	28/18722	0.000500834647669204	0.00372367767783795	CD74/NCKAP1L/C5AR1/C3AR1/RAC2/CAMK1D/ADAM8/CXCL8/C1QBP/MDK	10
GO:0002228	natural killer cell mediated immunity	18/2053	71/18722	0.000505196147377625	0.00375145653993286	HLA-B/HLA-A/CORO1A/HLA-F/LGALS9/HLA-E/HAVCR2/LILRB1/TUBB/SLAMF7/ARRB2/CADM1/PTPN6/LYST/TUBB4B/VAV1/PRDX1/IL18	18
GO:0002281	macrophage activation involved in immune response	8/2053	19/18722	0.000511446496119856	0.00377916130137825	TYROBP/HAVCR2/HMGB1/GRN/SYK/TREM2/CX3CR1/IFI35	8
GO:0002523	leukocyte migration involved in inflammatory response	8/2053	19/18722	0.000511446496119856	0.00377916130137825	S100A8/ALOX5/NLRP3/S100A9/ADAM8/JAM3/MDK/PTN	8
GO:0002716	negative regulation of natural killer cell mediated immunity	8/2053	19/18722	0.000511446496119856	0.00377916130137825	HLA-B/HLA-A/HLA-F/LGALS9/HLA-E/HAVCR2/LILRB1/ARRB2	8
GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	8/2053	19/18722	0.000511446496119856	0.00377916130137825	HLA-A/NCKAP1L/HLA-E/LILRB1/LILRB4/RUNX1/IRF1/RUNX3	8
GO:0045920	negative regulation of exocytosis	11/2053	33/18722	0.000523287769199897	0.0038619023557188	HLA-F/SPI1/LGALS9/NCKAP1L/CD84/CD300A/HMOX1/CCR2/NOTCH1/GNAI2/RAP1A	11
GO:0002468	dendritic cell antigen processing and presentation	7/2053	15/18722	0.000546617237186936	0.00401924439108041	HLA-DRA/CD68/HLA-DRB1/FGL2/CD74/SLC11A1/CLEC4A	7
GO:0071474	cellular hyperosmotic response	7/2053	15/18722	0.000546617237186936	0.00401924439108041	SLC2A1/RCSD1/AKR1B1/XRCC5/XRCC6/ARHGEF2/EFHD1	7
GO:2000104	negative regulation of DNA-dependent DNA replication	7/2053	15/18722	0.000546617237186936	0.00401924439108041	GMNN/BCL6/FBXO5/BLM/BRCA2/TIPIN/TIMELESS	7
GO:0009620	response to fungus	16/2053	60/18722	0.000557636404993409	0.00409524899627962	S100A8/SPI1/CLEC7A/COTL1/S100A12/SCIMP/CLEC4E/TLR4/BTK/SYK/S100A9/HAMP/CX3CR1/USP15/MYD88/GAPDH	16
GO:0007599	hemostasis	41/2053	222/18722	0.000571883417237807	0.00415365272171943	FCER1G/SERPINA1/PLEK/FLNA/LYN/PLAUR/WAS/CD9/FERMT3/FBLN1/F5/FN1/ACTB/JAK2/PRDX2/TLR4/LMAN1/CD36/GNAS/SYK/PTPN6/PPIA/HPSE/VAV1/FLI1/CD59/SH2B3/ENTPD1/ANXA5/CLIC1/IL6ST/PLSCR1/DGKD/VCL/VAV3/C1QTNF1/VKORC1/UBASH3B/PDGFA/MAPK14/SERPING1	41
GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	14/2053	49/18722	0.000572511800143661	0.00415365272171943	PTPRC/TGFB1/HSPD1/STAT6/IL27RA/UNG/BCL6/MSH2/MSH6/ERCC1/RNF8/RIF1/TFRC/EXO1	14
GO:0002208	somatic diversification of immunoglobulins involved in immune response	14/2053	49/18722	0.000572511800143661	0.00415365272171943	PTPRC/TGFB1/HSPD1/STAT6/IL27RA/UNG/BCL6/MSH2/MSH6/ERCC1/RNF8/RIF1/TFRC/EXO1	14
GO:0002279	mast cell activation involved in immune response	14/2053	49/18722	0.000572511800143661	0.00415365272171943	LGALS9/CD84/LYN/LAT2/CD300A/RAC2/FGR/HMOX1/STXBP2/ADGRE2/BTK/SYK/SNX4/S100A13	14
GO:0002762	negative regulation of myeloid leukocyte differentiation	14/2053	49/18722	0.000572511800143661	0.00415365272171943	CCL3/MAFB/LYN/LILRB1/LILRB3/LILRB4/FBN1/TLR4/RARA/TRIB1/CDK6/INPP5D/NME1/UBASH3B	14
GO:0009409	response to cold	14/2053	49/18722	0.000572511800143661	0.00415365272171943	PLAC8/FOS/UCP2/SOD2/METRNL/HSPD1/CXCL10/NFKBIA/HSP90AA1/ATP2B1/ACADVL/ADRB1/EIF2AK4/SLC9A1	14
GO:0030225	macrophage differentiation	14/2053	49/18722	0.000572511800143661	0.00415365272171943	HLA-DRB1/CSF1R/SPI1/TGFB1/TLR2/VEGFA/CD4/PARP1/APP/GAB3/TRIB1/HCLS1/EIF2AK1/ID2	14
GO:0045190	isotype switching	14/2053	49/18722	0.000572511800143661	0.00415365272171943	PTPRC/TGFB1/HSPD1/STAT6/IL27RA/UNG/BCL6/MSH2/MSH6/ERCC1/RNF8/RIF1/TFRC/EXO1	14
GO:0052372	modulation by symbiont of entry into host	14/2053	49/18722	0.000572511800143661	0.00415365272171943	HLA-DRB1/LGALS1/CD74/FCN1/IFITM2/LGALS9/TRIM22/IFITM3/CD4/P4HB/CIITA/CXCL8/ITGAV/TRIM38	14
GO:0070169	positive regulation of biomineral tissue development	14/2053	49/18722	0.000572511800143661	0.00415365272171943	ISG15/TGFB1/SLC8A1/MEF2C/FBN2/ALOX5/CEBPB/BMP7/ATP2B1/P2RX7/TFAP2A/FBXO5/ATRAID/PTN	14
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	17/2053	66/18722	0.000587823251237211	0.00424932470773887	PTPRC/TGFB1/HMGB1/HMGB2/HSPD1/PRKDC/STAT6/IL27RA/UNG/BCL6/MSH2/MSH6/ERCC1/RNF8/RIF1/TFRC/EXO1	17
GO:0016444	somatic cell DNA recombination	17/2053	66/18722	0.000587823251237211	0.00424932470773887	PTPRC/TGFB1/HMGB1/HMGB2/HSPD1/PRKDC/STAT6/IL27RA/UNG/BCL6/MSH2/MSH6/ERCC1/RNF8/RIF1/TFRC/EXO1	17
GO:0042093	T-helper cell differentiation	17/2053	66/18722	0.000587823251237211	0.00424932470773887	HLA-DRA/HLA-DRB1/CD86/HMGB1/PTGER4/STAT6/NLRP3/RARA/SEMA4A/BCL6/IL6R/GPR183/SPN/STAT3/GATA3/NFKBIZ/IL18	17
GO:0045638	negative regulation of myeloid cell differentiation	21/2053	90/18722	0.000602160808350722	0.00434773146823626	CCL3/ZFP36/MAFB/LYN/LILRB1/LILRB3/LILRB4/FBN1/TLR4/NFKBIA/RARA/ZFP36L1/PTK2B/TRIB1/CIB1/CDK6/INPP5D/NME1/UBASH3B/HSPA9/MEIS2	21
GO:0042273	ribosomal large subunit biogenesis	18/2053	72/18722	0.00060556936571242	0.00436708677196457	RPLP0/RPL5/NPM1/RPL7A/RPL23A/RPL35/RPL3/NHP2/RPL10A/MRPL20/RPL14/SNU13/MRPL1/RPL7/BRIX1/MALSU1/DDX18/MRTO4	18
GO:0010921	regulation of phosphatase activity	20/2053	84/18722	0.000610982962456465	0.00439556088098176	PTPRC/PLEK/NCKAP1L/MEF2C/CD300A/JAK2/HSP90B1/TNF/HSP90AB1/LGALS3/CD33/SLC39A10/GNAI2/CHP1/CALM2/MASTL/FKBP1A/PPP1R15A/PPP1R35/URI1	20
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	20/2053	84/18722	0.000610982962456465	0.00439556088098176	KLF4/PRKDC/PLK3/GPNMB/CCND1/CTDSPL/WEE1/EZH2/RPA2/TRIAP1/SOX4/BRD7/GTSE1/RBL1/DLG1/CDKN1A/CDK2AP2/CDK2/PLK2/E2F7	20
GO:0051271	negative regulation of cellular component movement	61/2053	367/18722	0.000612254309161873	0.00439725775807379	AIF1/TIMP1/CD74/BST2/ARHGDIB/TGFB1/WAS/CD9/MEF2C/FBLN1/CD300A/DUSP1/HMGB1/KLF4/SPINT2/TCAF1/CDH1/TNF/SERPINF1/GSTP1/HMOX1/ADGRG1/PTGER4/CNN2/VASH1/DAG1/IL27RA/DPP4/ENG/NOTCH1/NR2F2/CALR/MCTP1/ARHGAP4/LDLRAD4/RRAS/IDH2/GJA1/CX3CR1/KANK1/TACSTD2/TRIB1/RHOA/MARVELD3/STAT3/RIN3/RGCC/GATA3/DLG5/SEMA6D/ABHD2/SP100/APEX1/VCL/CORO1C/RHOB/TGFBR3/PTN/CCDC125/PTPRU/PPARG	61
GO:0070373	negative regulation of ERK1 and ERK2 cascade	19/2053	78/18722	0.000612684580958281	0.00439725775807379	PTPRC/LYN/FBLN1/DUSP1/KLF4/TLR4/DUSP9/GSTP1/GBP1/CSK/TIMP3/SEMA6A/NLRP12/SIRPA/PHB/EZR/DLG1/ATF3/EIF3A	19
GO:0033673	negative regulation of kinase activity	43/2053	237/18722	0.000625237305581727	0.00448198785363245	PTPRC/PYCARD/LYN/SORL1/SLC8A1/CD300A/LILRB4/DUSP1/TNFAIP3/IRAK3/IL1B/GSTP1/PTPN6/CSK/BMP7/PKIB/PPIA/HHEX/GADD45B/NR2F2/NPM1/SH2B3/CDKN1C/TRIB1/CHP1/PRDX3/LRP5/CDKN2A/RGS2/PARK7/CORO1C/MVP/CDKN1A/IPO5/IPO7/MIDN/VPS25/UBASH3B/MLLT1/PKN1/PRKAG2/PPARG/NCAPG2	43
GO:0045124	regulation of bone resorption	13/2053	44/18722	0.000627692980240207	0.00449422181556234	CSF1R/EGFR/SPP1/TNFAIP3/SYK/CSK/ADAM8/PDK4/HAMP/P2RX7/INPP5D/TFRC/UBASH3B	13
GO:0051043	regulation of membrane protein ectodomain proteolysis	9/2053	24/18722	0.000633153726026747	0.00451714905607667	TIMP1/TNFRSF1B/TNF/IL1B/TIMP2/TIMP3/ADAM8/PTPN3/PACSIN3	9
GO:0090023	positive regulation of neutrophil chemotaxis	9/2053	24/18722	0.000633153726026747	0.00451714905607667	CD74/NCKAP1L/C5AR1/C3AR1/RAC2/CAMK1D/CXCL8/C1QBP/MDK	9
GO:1903077	negative regulation of protein localization to plasma membrane	9/2053	24/18722	0.000633153726026747	0.00451714905607667	TGFB1/ABI3/GBP1/CSK/GOPC/RHOQ/NUMB/PICALM/AP2M1	9
GO:0038066	p38MAPK cascade	15/2053	55/18722	0.00063532303559014	0.00452724253389649	NCF1/ZFP36/SPI1/LGALS9/DUSP1/VEGFA/IL1B/GADD45B/ZFP36L1/TREM2/SPHK1/EZR/DLG1/MAP3K4/MAPK14	15
GO:0002347	response to tumor cell	12/2053	39/18722	0.000672547856901346	0.00477548774131133	HLA-A/LAPTM5/TXNIP/HLA-DRB1/SPI1/HAVCR2/HMGB1/ABI3/KLF4/PRDX2/HSPD1/IL4I1	12
GO:0016572	histone phosphorylation	12/2053	39/18722	0.000672547856901346	0.00477548774131133	JAK2/IL1B/CDK1/VRK1/PRKCB/CHEK1/BAZ1B/CCNA2/CDK2/AURKB/RPS6KA5/PKN1	12
GO:0051084	'de novo' posttranslational protein folding	12/2053	39/18722	0.000672547856901346	0.00477548774131133	CD74/HSPE1/HSPA5/HSPA8/HSPA6/CCT2/SDF2L1/HSPA14/HSPA1A/HSPA9/ST13/DNAJB14	12
GO:0120162	positive regulation of cold-induced thermogenesis	22/2053	97/18722	0.000682747536601484	0.00483646424983342	CXCR4/PLAC8/UCP2/JAK2/VEGFA/CD36/G0S2/CEBPB/GNAS/CCR2/STAT6/SYK/TRPV2/GJA1/EPAS1/ADRB1/FABP5/HADH/FH/IGF1R/KDM6B/IL18	22
GO:1901216	positive regulation of neuron death	22/2053	97/18722	0.000682747536601484	0.00483646424983342	TYROBP/ITGB2/CCL3/FOS/ITGAM/TNF/TLR4/PARP1/GRN/TLR6/CTSZ/C1QA/DDIT4/MCL1/TFAP2A/TRPM2/RHOA/MYBL2/FIS1/JUN/BAD/PICALM	22
GO:0021782	glial cell development	25/2053	116/18722	0.000686647707084799	0.00485835641805282	VIM/S100A8/C5AR1/LYN/CD9/TLR2/EGFR/TNF/TLR4/GSTP1/APP/GRN/DAG1/SOD1/S100A9/ITGB4/TREM2/C1QA/PARD3/SOX4/CDK6/IFNGR1/MDK/ADGRG6/NDRG1	25
GO:0007596	blood coagulation	40/2053	217/18722	0.000689098767803033	0.00485863133828772	FCER1G/SERPINA1/PLEK/FLNA/LYN/PLAUR/WAS/CD9/FERMT3/FBLN1/F5/FN1/ACTB/JAK2/PRDX2/TLR4/LMAN1/CD36/GNAS/SYK/PTPN6/PPIA/HPSE/VAV1/CD59/SH2B3/ENTPD1/ANXA5/CLIC1/IL6ST/PLSCR1/DGKD/VCL/VAV3/C1QTNF1/VKORC1/UBASH3B/PDGFA/MAPK14/SERPING1	40
GO:0000305	response to oxygen radical	10/2053	29/18722	0.000689925650036856	0.00485863133828772	UCP2/SOD2/PRDX2/CD36/SOD1/BMP7/DHFR/PRDX1/SOD3/GCH1	10
GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	10/2053	29/18722	0.000689925650036856	0.00485863133828772	GPX1/SOD2/PARP1/P4HB/SOD1/PPIA/TREM2/MCL1/PARK7/TRAP1	10
GO:2000406	positive regulation of T cell migration	10/2053	29/18722	0.000689925650036856	0.00485863133828772	AIF1/PYCARD/TNFRSF14/APP/ITGA4/CCR2/CXCL10/ADAM8/SPN/RHOA	10
GO:0002446	neutrophil mediated immunity	11/2053	34/18722	0.000697637806550297	0.00488817871621394	ITGB2/SPI1/ITGAM/TREM1/PTAFR/STXBP2/PRAM1/SYK/MYD88/ANXA3/KMT2E	11
GO:0032212	positive regulation of telomere maintenance via telomerase	11/2053	34/18722	0.000697637806550297	0.00488817871621394	PKIB/HNRNPA1/TCP1/CCT6A/CCT2/XRCC5/PNKP/CCT4/AURKB/CCT8/MAP3K4	11
GO:0051085	chaperone cofactor-dependent protein refolding	11/2053	34/18722	0.000697637806550297	0.00488817871621394	CD74/HSPE1/HSPA5/HSPA8/HSPA6/SDF2L1/HSPA14/HSPA1A/HSPA9/ST13/DNAJB14	11
GO:0051973	positive regulation of telomerase activity	11/2053	34/18722	0.000697637806550297	0.00488817871621394	KLF4/HSP90AA1/HSP90AB1/PKIB/TCP1/CCT2/XRCC5/PNKP/CCT4/AURKB/MAP3K4	11
GO:0031667	response to nutrient levels	75/2053	474/18722	0.000698194859965891	0.00488817871621394	TSPO/CD68/CYBB/CYBA/ZFP36/SORL1/SLC8A1/PAGE4/EGFR/UCP2/SOD2/SPP1/UPP1/LRRK2/TYMS/IFI16/GSTP1/STAT1/HMOX1/NAMPT/SLC2A1/KYNU/CXCL10/KRT18/GLUL/AGL/SOD1/RARA/BMP7/SRSF2/ATP2B1/PDK4/COMT/HSPA5/HAMP/ICAM1/CCND1/CTSV/HNRNPA1/HSPA8/GNAI2/PMAIP1/HAT1/SLC6A4/ADRB1/LDHA/VDR/ACSL4/SLC16A1/FOLR1/GCLM/RALB/ASS1/TRIM24/EIF2AK4/NENF/FIS1/FOXO4/JUN/CSH1/ERCC1/EIF2AK1/CDKN1A/BNIP3/ENSA/ATF3/PTN/GABARAP/MBD2/EIF4G1/MBD3/WIPI2/PRKAG2/PPARG/ALAD	75
GO:0051983	regulation of chromosome segregation	21/2053	91/18722	0.000703261289812425	0.00491791111756941	DUSP1/MKI67/CENPF/ZWINT/MAD2L1/CDC6/ANAPC11/RMI2/UBE2C/CDT1/FBXO5/RAD21/BUB3/PLSCR1/TPR/NDC80/TTK/AURKB/LCMT1/BUB1B/KNTC1	21
GO:0002448	mast cell mediated immunity	14/2053	50/18722	0.000715925105263828	0.00498323739162757	LGALS9/CD84/LYN/LAT2/CD300A/RAC2/FGR/HMOX1/STXBP2/ADGRE2/BTK/SYK/SNX4/S100A13	14
GO:0038093	Fc receptor signaling pathway	14/2053	50/18722	0.000715925105263828	0.00498323739162757	FCER1G/PTPRC/LYN/HCK/MYO1G/FGR/FCGR1B/BTK/SYK/VAV1/RAP1A/VAV3/YES1/PTK2	14
GO:0045058	T cell selection	14/2053	50/18722	0.000715925105263828	0.00498323739162757	PTPRC/CD74/CTSL/CD4/DOCK2/STAT6/SYK/CD1D/IL6R/SPN/RHOA/STAT3/GATA3/GLI3	14
GO:0110151	positive regulation of biomineralization	14/2053	50/18722	0.000715925105263828	0.00498323739162757	ISG15/TGFB1/SLC8A1/MEF2C/FBN2/ALOX5/CEBPB/BMP7/ATP2B1/P2RX7/TFAP2A/FBXO5/ATRAID/PTN	14
GO:2000779	regulation of double-strand break repair	20/2053	85/18722	0.00071795572702	0.00499158095263036	WAS/PARP1/DEK/PRKDC/FUS/RAD51AP1/PARP9/RAD51/RMI2/CHEK1/RPA2/ACTR2/PNKP/DTX3L/MAGEF1/TIMELESS/RIF1/POLQ/FOXM1/FIGNL1	20
GO:0050848	regulation of calcium-mediated signaling	18/2053	73/18722	0.000722629539857732	0.00501826069345647	CCL3/PLEK/CCL4/CLEC7A/LRRK2/CD4/TNF/HOMER3/GBP1/SYK/TREM2/PTK2B/CHP1/CALM2/CIB1/SLC9A1/FHL2/NFAT5	18
GO:0030168	platelet activation	26/2053	123/18722	0.00073856445930316	0.00512299046915487	FCER1G/PLEK/FLNA/LYN/CD9/FERMT3/FN1/ACTB/JAK2/TLR4/GNAS/SYK/PTPN6/PPIA/VAV1/SH2B3/CLIC1/IL6ST/PLSCR1/DGKD/VCL/VAV3/C1QTNF1/UBASH3B/PDGFA/MAPK14	26
GO:0034655	nucleobase-containing compound catabolic process	66/2053	407/18722	0.000740340822227539	0.00512938214014461	VIM/SLC11A1/APOBEC3A/TYMP/TNFRSF1B/ZFP36/SAMHD1/ZFP36L2/OAS2/DUT/UPP1/HINT1/ISG20/RNASE6/DPYD/FEN1/FUS/CARHSP1/PABPC1/RNASET2/UNG/LIN28B/ZFP36L1/NPM1/CDA/HNRNPR/ENTPD1/PDE4A/SERBP1/BTG2/EXOSC8/APOBEC3G/LSM2/NUDT8/APOBEC3C/RNASEH2A/LSM4/SLIRP/LSM5/NUDT15/HNRNPD/UPF3A/PNP/MAGOHB/LSM7/MYD88/MAGOH/KHSRP/SND1/HNRNPA0/DNASE1L1/NUDT4/NUDT5/APEX1/HSPA1A/DCTPP1/AGO2/AMPD3/SMPDL3A/VCP/LRPPRC/DNPH1/E2F1/MRTO4/YBX1/MAPK14	66
GO:0051403	stress-activated MAPK cascade	43/2053	239/18722	0.000747300902071993	0.00517163254029061	NCF1/ZFP36/SPI1/LGALS9/CLEC7A/PYCARD/PAGE4/DUSP1/SCIMP/HMGB1/EGFR/LRRK2/VEGFA/HACD3/TNF/TLR4/DUSP9/IL1B/GSTP1/APP/PTGER4/TLR7/PPIA/GADD45B/ZFP36L1/TREM2/PTK2B/PBK/HRAS/TRIB1/SPHK1/MARVELD3/SIRPA/SDCBP/MYD88/PRDX1/RASSF2/EZR/DLG1/IGF1R/FOXM1/MAP3K4/MAPK14	43
GO:0071248	cellular response to metal ion	37/2053	197/18722	0.000748403045393198	0.00517329294050598	TSPO/CYBB/NCF1/B2M/MEF2C/FOS/EGFR/ALOX5AP/JUNB/LRRK2/CDH1/FBP1/PARP1/SERPINF1/APP/HMOX1/HVCN1/FUS/MEF2A/SOD1/MT1X/CALR/HSD17B1/HSPA5/FOSB/CAMK2D/TFAP2A/TRPM2/RASGRP2/MT2A/SYT7/CACYBP/ANK3/JUN/ECT2/BNIP3/ALAD	37
GO:0050769	positive regulation of neurogenesis	41/2053	225/18722	0.00075509345842921	0.00521353366004057	TSPO/CXCR4/TNFRSF1B/TGFB1/LYN/TLR2/FN1/SPINT1/SKIL/EGFR/VEGFA/PLXNC1/LRP2/TNF/IL1B/SERPINF1/TGM2/DAG1/MME/NOTCH1/TRPV2/ASPM/CX3CR1/NAP1L1/NRP1/ACTR2/RHEB/HDAC2/GOLGA4/IL6ST/TWF2/XRCC5/OBSL1/GLI3/ID2/NUMB/MDK/PTN/PRPF19/E2F1/XRCC2	41
GO:0002577	regulation of antigen processing and presentation	8/2053	20/18722	0.000770904500925443	0.00529225057843554	CD68/FGL2/CD74/SLC11A1/PYCARD/WAS/LILRB2/TREM2	8
GO:0032495	response to muramyl dipeptide	8/2053	20/18722	0.000770904500925443	0.00529225057843554	VIM/TNFAIP3/NFKBIA/NOTCH1/IRF5/NLRP1/ARHGEF2/MAPK14	8
GO:0072567	chemokine (C-X-C motif) ligand 2 production	8/2053	20/18722	0.000770904500925443	0.00529225057843554	CD74/HMGB1/KLF4/MBP/TNF/TLR4/OAS1/MYD88	8
GO:0140632	inflammasome complex assembly	8/2053	20/18722	0.000770904500925443	0.00529225057843554	GBP5/TLR4/CD36/TLR6/TREM2/AIM2/NLRP1/MYD88	8
GO:2000341	regulation of chemokine (C-X-C motif) ligand 2 production	8/2053	20/18722	0.000770904500925443	0.00529225057843554	CD74/HMGB1/KLF4/MBP/TNF/TLR4/OAS1/MYD88	8
GO:1903828	negative regulation of cellular protein localization	25/2053	117/18722	0.000783940521462897	0.00537559214717415	SPI1/TGFB1/LILRB4/ABI3/LRRK2/LMAN1/CD36/GBP1/MAGED1/CSK/CDT1/FERMT1/CHP1/BARD1/TRIM29/TXN/SVIP/GOPC/SP100/RHOQ/PARK7/COMMD1/NUMB/PICALM/AP2M1	25
GO:0001959	regulation of cytokine-mediated signaling pathway	30/2053	150/18722	0.000800392981854074	0.00548214371132928	LAPTM5/PTPRC/CD74/CXCR4/ISG15/SAMHD1/PYCARD/CASP1/TNFAIP3/IRAK3/GSTP1/IL1RN/CD300LF/IRF7/CD24/SYK/HSP90AB1/CARD16/PTPN6/PARP9/TREM2/SH2B3/AGPAT2/OAS1/NLRC5/SPHK1/STAT2/HSPA1A/PARP14/PPARG	30
GO:1902750	negative regulation of cell cycle G2/M phase transition	16/2053	62/18722	0.000824618641900941	0.00564163266978979	CLSPN/CDK1/CDC6/BRCA1/NAE1/DTL/CHEK1/RAD21/TOPBP1/BLM/ATF5/FOXO4/CDKN1A/AURKB/CHMP4C/BRCC3	16
GO:1990845	adaptive thermogenesis	31/2053	157/18722	0.000827263569387546	0.00565328179535909	CXCR4/SORL1/PLAC8/UCP2/JAK2/VEGFA/TLR4/CD36/G0S2/CEBPB/GNAS/CCR2/STAT6/SYK/SLC25A5/NOTCH1/TRPV2/ID1/GJA1/ALDH1A1/EPAS1/ADRB1/FABP5/RHEB/SLC25A4/HADH/FH/LGR4/IGF1R/KDM6B/IL18	31
GO:0050767	regulation of neurogenesis	60/2053	364/18722	0.000834939377029091	0.00569924489439653	TSPO/CXCR4/TNFRSF1B/TGFB1/LYN/SORL1/B2M/TLR2/FN1/SPINT1/SKIL/EGFR/SPP1/VEGFA/PLXNC1/LRP2/TNF/HMGB2/IL1B/SERPINF1/TGM2/DAG1/MME/BMP7/SEMA4A/NOTCH1/TREM2/ARHGAP4/TRPV2/SEMA6A/ID1/IDH2/ASPM/EZH2/CX3CR1/NAP1L1/ASCL2/NRP1/ACTR2/RHEB/HDAC2/GOLGA4/IL6ST/TWF2/BHLHE40/SEMA6D/XRCC5/YAP1/OBSL1/PRTG/GLI3/ID2/NUMB/MDK/BHLHE41/PTN/PRPF19/E2F1/XRCC2/DYNLT1	60
GO:0031647	regulation of protein stability	51/2053	298/18722	0.00084756832519823	0.00577887494453339	TYROBP/IFI30/FLNA/PYCARD/LRRK2/HSPD1/GRN/RPS7/PRKDC/CTSH/HSP90AA1/DDOST/HSP90AB1/RPL5/PPIB/CALR/RPL23/NPM1/PHB2/ASGR2/HSPA8/AAK1/CHP1/SOX4/RNF149/TCP1/USP27X/CCT6A/MFSD1/PLPP3/CCT2/TRIM24/EFNA1/BAG2/USP3/PHB/PFN1/SIAH1/RASSF2/PARK7/HSPA1A/TBL1X/CCT4/STK4/P3H1/CCT8/CTNND1/LMNA/DPM2/MYLIP/GAPDH	51
GO:0046686	response to cadmium ion	17/2053	68/18722	0.000849492458189494	0.00578541969255047	CYBB/NCF1/B2M/FOS/EGFR/SOD2/PCNA/HMOX1/SOD1/MT1X/CDK1/CYB5A/DTYMK/MT2A/JUN/ERCC1/ALAD	17
GO:0009636	response to toxic substance	46/2053	262/18722	0.000857479157620307	0.00583319154843746	CCL3/CCL4/LYN/TLR2/FOS/GPX1/SOD2/ALOX5AP/MBP/TYMS/MGST3/CDH1/PRDX2/CD36/GSTP1/PRDX4/GLRX/PRDX5/SOD1/MT1X/CDK1/BMP7/S100A9/DHFR/RAD51/GPX8/ADH5/PON2/ALDH1A1/SLC6A4/MT2A/TXN/PRDX3/CDK4/PRDX6/ASS1/PRDX1/MGST1/SOD3/FIS1/PARK7/GCH1/CDKN1A/PTGES/KDM6B/ALAD	46
GO:1903201	regulation of oxidative stress-induced cell death	18/2053	74/18722	0.000858574357396075	0.00583402734357469	PAGE4/GPX1/SOD2/LRRK2/TLR4/PARP1/P4HB/MET/TLR6/SOD1/PPIA/TREM2/MCL1/PAWR/TRPM2/TXN/PARK7/TRAP1	18
GO:0010631	epithelial cell migration	59/2053	357/18722	0.000859956231011728	0.00583680699781716	TMSB4X/ZEB2/TGFB1/MEF2C/HMGB1/GPX1/KLF4/VEGFA/TNF/SERPINF1/HMOX1/GRN/MET/GLIPR2/NRP2/CTSH/VASH1/GLUL/ITGB1/DPP4/SEMA4A/NOTCH1/NR2F2/CALR/TNFSF12/PTK2B/NR4A1/EMP2/FSTL1/STAT5A/RRAS/ID1/HBEGF/KANK1/TACSTD2/FERMT1/AMOT/NRP1/RHOA/CIB1/MARVELD3/RGCC/GATA3/EPHB4/PLPP3/ANLN/EFNA1/RAB25/ANXA3/PFN1/SP100/BCAR1/CORO1C/RHOB/PLK2/PTN/PTK2/PKN1/PPARG	59
GO:0010543	regulation of platelet activation	12/2053	40/18722	0.000866011023040491	0.00585802270376882	FCER1G/PLEK/LYN/CD9/JAK2/TLR4/SYK/SH2B3/IL6ST/C1QTNF1/UBASH3B/PDGFA	12
GO:0030501	positive regulation of bone mineralization	12/2053	40/18722	0.000866011023040491	0.00585802270376882	ISG15/TGFB1/SLC8A1/MEF2C/FBN2/ALOX5/BMP7/ATP2B1/P2RX7/TFAP2A/ATRAID/PTN	12
GO:2000781	positive regulation of double-strand break repair	12/2053	40/18722	0.000866011023040491	0.00585802270376882	WAS/PARP1/PRKDC/FUS/RAD51AP1/PARP9/ACTR2/PNKP/DTX3L/TIMELESS/RIF1/FOXM1	12
GO:0002830	positive regulation of type 2 immune response	7/2053	16/18722	0.000880102028890909	0.00593327210488253	CD74/CD86/NLRP3/RARA/RSAD2/GATA3/IL18	7
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	7/2053	16/18722	0.000880102028890909	0.00593327210488253	LGALS9/CLEC7A/CD84/HMGB1/IL1B/SYK/OAS1	7
GO:1901163	regulation of trophoblast cell migration	7/2053	16/18722	0.000880102028890909	0.00593327210488253	TIMP1/ARHGDIB/VEGFA/CALR/GJA1/C1QBP/AGO2	7
GO:0032490	detection of molecule of bacterial origin	6/2053	12/18722	0.000887193865695987	0.00593695011361564	LY96/TLR2/TLR1/TLR4/TLR6/TREM2	6
GO:0034154	toll-like receptor 7 signaling pathway	6/2053	12/18722	0.000887193865695987	0.00593695011361564	PIK3AP1/HAVCR2/SCIMP/TLR7/RSAD2/UNC93B1	6
GO:0071635	negative regulation of transforming growth factor beta production	6/2053	12/18722	0.000887193865695987	0.00593695011361564	TYROBP/LILRB1/FN1/CD24/HSP90AB1/CD2AP	6
GO:0140052	cellular response to oxidised low-density lipoprotein particle stimulus	6/2053	12/18722	0.000887193865695987	0.00593695011361564	CD68/TLR4/CD36/TLR6/TREM2/MYD88	6
GO:1903332	regulation of protein folding	6/2053	12/18722	0.000887193865695987	0.00593695011361564	GRN/HSPA5/PDCD5/SGTB/SNRNP70/ST13	6
GO:1904816	positive regulation of protein localization to chromosome, telomeric region	6/2053	12/18722	0.000887193865695987	0.00593695011361564	TCP1/CCT6A/CCT2/GNL3/CCT4/CCT8	6
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	14/2053	51/18722	0.000888563533671141	0.00593695011361564	NDUFA10/NDUFB9/NDUFB4/NDUFB7/NDUFA6/NDUFAB1/NDUFV1/NDUFS8/NDUFV2/PARK7/NDUFS6/NDUFC2/NDUFB10/NDUFA8	14
GO:0071622	regulation of granulocyte chemotaxis	14/2053	51/18722	0.000888563533671141	0.00593695011361564	CD74/CSF1R/NCKAP1L/C5AR1/C3AR1/RAC2/CAMK1D/DPP4/CXCL8/C1QBP/JAM3/MPP1/MDK/PTK2	14
GO:0042832	defense response to protozoan	9/2053	25/18722	0.000893781975753011	0.00595193324585801	SLC11A1/CLEC7A/GBP4/GBP2/IRF8/LYST/HRAS/CCDC88B/MYD88	9
GO:0071450	cellular response to oxygen radical	9/2053	25/18722	0.000893781975753011	0.00595193324585801	SOD2/PRDX2/CD36/SOD1/BMP7/DHFR/PRDX1/SOD3/GCH1	9
GO:0071451	cellular response to superoxide	9/2053	25/18722	0.000893781975753011	0.00595193324585801	SOD2/PRDX2/CD36/SOD1/BMP7/DHFR/PRDX1/SOD3/GCH1	9
GO:0043433	negative regulation of DNA-binding transcription factor activity	35/2053	185/18722	0.000895284804056221	0.00595533129083961	TMSB4X/SPI1/FLNA/PYCARD/HAVCR2/KLF4/PRDX2/TNFAIP3/IRAK3/HMOX1/ARRB2/NFKBIA/NLRP3/BMP7/AIM2/ID1/PHB2/EZH2/NLRP12/NLRC5/TRIB1/CHP1/HDAC2/BHLHE40/ID3/NFKBIE/CDKN2A/SP100/EIF2AK4/COMMD7/COMMD1/TAX1BP1/ID2/PURA/COMMD6	35
GO:0046777	protein autophosphorylation	41/2053	227/18722	0.000904400281215097	0.00600930419412025	PTPRC/CSF1R/LYN/HCK/EGFR/FGR/JAK2/LRRK2/VEGFA/IRAK3/BTK/GPNMB/SYK/CSK/ENG/PTK2B/VRK1/FLT1/CAMK2D/NLRP12/AAK1/CHP1/CALM2/MAPKAPK3/EPHB4/TRIM24/RAD50/EIF2AK4/RASSF2/TTK/STK17B/MVP/EIF2AK1/IGF1R/YES1/AURKB/STK4/INSR/TRIM28/PTK2/PDGFA	41
GO:0042254	ribosome biogenesis	51/2053	299/18722	0.000915432935459812	0.00607588231499875	RPS21/ISG20/PA2G4/RPS5/RPS17/RPS7/RPSA/RPS27/PRKDC/GLUL/RPS16/RPLP0/RAN/RPS14/RPL5/NPM1/RPL7A/POP7/RPL23A/EXOSC8/RPS19/NOP56/C1QBP/RPL35/RPL3/NHP2/RPL10A/MRPL20/NOP58/RPL14/RBFA/RPS6/RPS8/SNU13/MRPL1/XRCC5/RPL7/IMP3/WDR18/SBDS/KRR1/BRIX1/MRPL36/MALSU1/WBP11/RPS25/DDX18/FBL/PWP1/MRTO4/BMS1	51
GO:0045454	cell redox homeostasis	11/2053	35/18722	0.000917644951373578	0.00608383393175853	SLC11A1/GPX1/PRDX2/PRDX4/HVCN1/PRDX5/TXN/PRDX3/PRDX6/PRDX1/APEX1	11
GO:0009264	deoxyribonucleotide catabolic process	10/2053	30/18722	0.00093414164129888	0.00616595142771538	TYMP/SAMHD1/DUT/UPP1/DPYD/UNG/NUDT15/PNP/DCTPP1/DNPH1	10
GO:0031571	mitotic G1 DNA damage checkpoint signaling	10/2053	30/18722	0.00093414164129888	0.00616595142771538	PRKDC/PLK3/CCND1/RPA2/TRIAP1/SOX4/GTSE1/CDKN1A/CDK2/PLK2	10
GO:0034508	centromere complex assembly	10/2053	30/18722	0.00093414164129888	0.00616595142771538	NASP/HELLS/CENPW/CENPF/CENPN/CENPK/ITGB3BP/CENPH/MIS18A/KNTC1	10
GO:0045070	positive regulation of viral genome replication	10/2053	30/18722	0.00093414164129888	0.00616595142771538	IFIT1/HACD3/PABPC1/TOP2A/PPIA/NOTCH1/DDB1/STAU1/SRPK1/TOP2B	10
GO:0032088	negative regulation of NF-kappaB transcription factor activity	21/2053	93/18722	0.000950133812662227	0.006257741905569	TMSB4X/SPI1/PYCARD/HAVCR2/KLF4/PRDX2/TNFAIP3/IRAK3/ARRB2/NFKBIA/NLRP3/BMP7/AIM2/NLRP12/NLRC5/CHP1/CDKN2A/COMMD7/COMMD1/TAX1BP1/COMMD6	21
GO:0033108	mitochondrial respiratory chain complex assembly	21/2053	93/18722	0.000950133812662227	0.006257741905569	SCO2/TFAM/NDUFA10/NDUFB9/COX20/UQCC2/NDUFB4/NDUFB7/NDUFB11/NDUFA6/NDUFAB1/COA4/NDUFS8/SCO1/TTC19/UQCRFS1/NDUFC2/NDUFA13/NDUFB10/COX17/NDUFA8	21
GO:0016447	somatic recombination of immunoglobulin gene segments	15/2053	57/18722	0.000954003487713962	0.00626946432232615	PTPRC/TGFB1/HSPD1/PRKDC/STAT6/IL27RA/UNG/BCL6/MSH2/MSH6/ERCC1/RNF8/RIF1/TFRC/EXO1	15
GO:0060760	positive regulation of response to cytokine stimulus	15/2053	57/18722	0.000954003487713962	0.00626946432232615	LAPTM5/CD74/CXCR4/TLR2/CASP1/TLR4/CD300LF/IRF7/PARP9/TREM2/AGPAT2/NLRC5/HSPA1A/PARP14/DDX58	15
GO:0061351	neural precursor cell proliferation	29/2053	145/18722	0.000969326808919463	0.00636319568218466	FLNA/C5AR1/LYN/SPINT1/SPINT2/LRRK2/VEGFA/LRP2/RRM1/ADGRG1/CTSZ/NOTCH1/BTG2/ASPM/CX3CR1/PSMG1/NAP1L1/GNAI2/SLC6A4/RHOA/ATF5/ARHGEF2/SHCBP1/RERE/GLI3/ID2/NUMB/MDK/PTN	29
GO:2000146	negative regulation of cell motility	59/2053	359/18722	0.00098827210959145	0.00648047284978	AIF1/TIMP1/CD74/BST2/ARHGDIB/TGFB1/WAS/MEF2C/FBLN1/CD300A/DUSP1/HMGB1/KLF4/SPINT2/TCAF1/CDH1/TNF/SERPINF1/GSTP1/HMOX1/ADGRG1/PTGER4/CNN2/VASH1/DAG1/IL27RA/DPP4/ENG/NOTCH1/NR2F2/CALR/MCTP1/ARHGAP4/LDLRAD4/RRAS/IDH2/GJA1/CX3CR1/KANK1/TACSTD2/TRIB1/RHOA/MARVELD3/STAT3/RIN3/RGCC/GATA3/DLG5/SEMA6D/ABHD2/SP100/APEX1/VCL/CORO1C/RHOB/PTN/CCDC125/PTPRU/PPARG	59
GO:0031343	positive regulation of cell killing	16/2053	63/18722	0.00099453080210817	0.00651439390027186	HLA-B/TYROBP/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/HLA-F/SPI1/CLEC7A/B2M/HLA-E/ITGAM/CADM1/SYK/CD1D/VAV1	16
GO:0061028	establishment of endothelial barrier	13/2053	46/18722	0.000998573162831425	0.00653373934240845	MSN/PECAM1/VEGFA/TNF/IL1B/MYADM/ICAM1/RDX/MYD88/TJP1/RAP1A/VCL/EZR	13
GO:0007004	telomere maintenance via telomerase	17/2053	69/18722	0.00101387294520989	0.00662662055692736	HSP90AA1/HSP90AB1/PKIB/HNRNPA1/NHP2/RFC1/TCP1/CCT6A/CCT2/XRCC5/RAD50/PNKP/RPA1/CCT4/AURKB/CCT8/MAP3K4	17
GO:0030282	bone mineralization	25/2053	119/18722	0.00101497881148904	0.00662662989002638	SRGN/CCL3/ISG15/TGFB1/SLC8A1/MEF2C/FBN2/FGR/SNX10/ALOX5/CCR1/GPNMB/BMP7/ATP2B1/PTK2B/NOTUM/P2RX7/BMP2K/ASGR2/TFAP2A/LGR4/ATRAID/SBDS/PTN/GPC3	25
GO:0090132	epithelium migration	59/2053	360/18722	0.00105859085242386	0.00690385338537297	TMSB4X/ZEB2/TGFB1/MEF2C/HMGB1/GPX1/KLF4/VEGFA/TNF/SERPINF1/HMOX1/GRN/MET/GLIPR2/NRP2/CTSH/VASH1/GLUL/ITGB1/DPP4/SEMA4A/NOTCH1/NR2F2/CALR/TNFSF12/PTK2B/NR4A1/EMP2/FSTL1/STAT5A/RRAS/ID1/HBEGF/KANK1/TACSTD2/FERMT1/AMOT/NRP1/RHOA/CIB1/MARVELD3/RGCC/GATA3/EPHB4/PLPP3/ANLN/EFNA1/RAB25/ANXA3/PFN1/SP100/BCAR1/CORO1C/RHOB/PLK2/PTN/PTK2/PKN1/PPARG	59
GO:0031623	receptor internalization	24/2053	113/18722	0.00107999619299127	0.00703580581753269	FCER1G/ITGB2/CD9/LILRB1/LILRB4/VEGFA/CD36/ARRB2/LRPAP1/SYK/ITGB1/CXCL8/RIN3/AHI1/SDCBP/GRB2/CD63/EZR/TFRC/NUMB/INSR/PICALM/AP2M1/LDLRAP1	24
GO:0009117	nucleotide metabolic process	76/2053	489/18722	0.00108379754383513	0.00705291243276657	TMSB4X/TYMP/TGFB1/SAMHD1/DUT/UPP1/GIMAP7/LRRK2/TYMS/HINT1/FBP1/PARP1/APP/RRM1/NAMPT/KYNU/DPYD/SLC26A2/RAN/MPC2/ACSS1/TECR/UNG/QPRT/PARP9/TREM2/HK3/CDA/PDK4/PAICS/DTYMK/P2RX7/PDE4A/RRM2/HK2/DDIT4/IDH2/PPT1/SLC2A6/SULT1A1/NUDT8/ALDOA/SLC25A1/LDHA/RHOA/UMPS/STAT3/NUDT15/PNP/ARL2/ACSL4/GMPS/DHTKD1/TPST2/PMVK/PDHA1/STOML2/NME4/ADK/NUDT4/IMPDH2/NUDT5/RHOQ/PARK7/DLG1/BAD/DCTPP1/MPP1/AMPD3/INSR/VCP/NME1/DNPH1/PPAT/GAPDH/PRKAG2	76
GO:0050817	coagulation	40/2053	222/18722	0.00108767834091392	0.00707049842414251	FCER1G/SERPINA1/PLEK/FLNA/LYN/PLAUR/WAS/CD9/FERMT3/FBLN1/F5/FN1/ACTB/JAK2/PRDX2/TLR4/LMAN1/CD36/GNAS/SYK/PTPN6/PPIA/HPSE/VAV1/CD59/SH2B3/ENTPD1/ANXA5/CLIC1/IL6ST/PLSCR1/DGKD/VCL/VAV3/C1QTNF1/VKORC1/UBASH3B/PDGFA/MAPK14/SERPING1	40
GO:0010718	positive regulation of epithelial to mesenchymal transition	14/2053	52/18722	0.00109495937890931	0.00710243921454686	TGFB1/IL1B/GLIPR2/BMP7/ENG/NOTCH1/EZH2/ISL1/HDAC2/RGCC/SDCBP/FERMT2/FOXC1/MDK	14
GO:0043277	apoptotic cell clearance	14/2053	52/18722	0.00109495937890931	0.00710243921454686	TYROBP/FCN1/RAC2/HMGB1/CD36/CD300LF/CCR2/C3/TGM2/RARA/TREM2/MARCO/ITGAV/RHOG	14
GO:0071692	protein localization to extracellular region	60/2053	368/18722	0.00109804452117494	0.00711475931646827	HLA-DRB1/PLEK/TGFB1/TLR2/EGFR/FBN2/UCP2/JAK2/FBN1/ALOX5/TNF/TLR4/IL1B/MYH10/WLS/IL1RN/GLUL/MPC2/SERP1/PPIA/DPP4/RSAD2/TREM2/ADAM8/PDIA4/CD33/RHBDF2/ERP29/IDH2/GJA1/FAM3B/HMGN3/UQCC2/TRPM2/KLF7/LTBP1/ISL1/SYT7/FRMD4A/SOX4/HADH/ACSL4/SLC16A1/LRP5/RAB3D/KCNN4/CYB5R4/CAMK2G/PARK7/PHPT1/EZR/BAD/TCIRG1/MIDN/DNAJC1/CD2AP/ENSA/P3H1/TM7SF3/CCDC186	60
GO:0071634	regulation of transforming growth factor beta production	12/2053	41/18722	0.00110370399305562	0.00714371516540852	TYROBP/LGALS9/LILRB1/FN1/CD24/CD46/HSP90AB1/FERMT1/LTBP1/ITGAV/CD2AP/ITGB8	12
GO:0030449	regulation of complement activation	8/2053	21/18722	0.00112642320201432	0.00722066155137382	IL1B/C3/CD46/TREM2/CD59/C1QBP/PHB/SERPING1	8
GO:0032516	positive regulation of phosphoprotein phosphatase activity	8/2053	21/18722	0.00112642320201432	0.00722066155137382	PTPRC/CD300A/JAK2/HSP90AB1/CD33/SLC39A10/CALM2/PPP1R15A	8
GO:0035455	response to interferon-alpha	8/2053	21/18722	0.00112642320201432	0.00722066155137382	BST2/IFITM2/IFIT2/IFITM3/MX2/IFIT3/GATA3/TPR	8
GO:0045655	regulation of monocyte differentiation	8/2053	21/18722	0.00112642320201432	0.00722066155137382	HLA-DRB1/CD74/CD4/IRF7/ZFP36L1/CDK6/JUN/INPP5D	8
GO:0046823	negative regulation of nucleocytoplasmic transport	8/2053	21/18722	0.00112642320201432	0.00722066155137382	CD36/FERMT1/CHP1/BARD1/TXN/TPR/SP100/PARK7	8
GO:0048714	positive regulation of oligodendrocyte differentiation	8/2053	21/18722	0.00112642320201432	0.00722066155137382	CXCR4/TNFRSF1B/TLR2/DAG1/RHEB/HDAC2/MDK/PTN	8
GO:0071605	monocyte chemotactic protein-1 production	8/2053	21/18722	0.00112642320201432	0.00722066155137382	LGALS9/CLEC7A/CD84/HMGB1/IL1B/GSTP1/SYK/OAS1	8
GO:0071637	regulation of monocyte chemotactic protein-1 production	8/2053	21/18722	0.00112642320201432	0.00722066155137382	LGALS9/CLEC7A/CD84/HMGB1/IL1B/GSTP1/SYK/OAS1	8
GO:0099515	actin filament-based transport	8/2053	21/18722	0.00112642320201432	0.00722066155137382	MYO1F/MYO1G/SYNE2/MYO1C/FNBP1L/MYO5A/ACTN4/MYO7A	8
GO:0009144	purine nucleoside triphosphate metabolic process	20/2053	88/18722	0.00114104176397017	0.00729877460961731	TMSB4X/TGFB1/SAMHD1/GIMAP7/LRRK2/PARP1/RAN/TREM2/ALDOA/RHOA/STAT3/NUDT15/STOML2/NME4/ADK/IMPDH2/RHOQ/VCP/NME1/PRKAG2	20
GO:1901657	glycosyl compound metabolic process	20/2053	88/18722	0.00114104176397017	0.00729877460961731	APOBEC3A/TYMP/UPP1/DPYD/AKR7A2/CDA/DTYMK/TK1/APOBEC3G/AKR1B1/APOBEC3C/FUCA1/MTAP/UMPS/PNP/ERH/NME4/ADK/DNPH1/PPAT	20
GO:0071901	negative regulation of protein serine/threonine kinase activity	25/2053	120/18722	0.00115111745241266	0.00735538308250898	PYCARD/LYN/SORL1/SLC8A1/CD300A/DUSP1/TNFAIP3/IRAK3/IL1B/GSTP1/PTPN6/BMP7/PKIB/HHEX/NR2F2/SH2B3/CDKN1C/LRP5/CDKN2A/RGS2/CDKN1A/IPO5/IPO7/PRKAG2/PPARG	25
GO:0043666	regulation of phosphoprotein phosphatase activity	15/2053	58/18722	0.00115830717014509	0.0073934500222027	PTPRC/NCKAP1L/CD300A/JAK2/HSP90B1/TNF/HSP90AB1/LGALS3/CD33/SLC39A10/GNAI2/CALM2/MASTL/FKBP1A/PPP1R15A	15
GO:0072527	pyrimidine-containing compound metabolic process	19/2053	82/18722	0.00117458170677146	0.00748936263616235	APOBEC3A/TYMP/DUT/UPP1/TYMS/RRM1/DPYD/UNG/CDA/DTYMK/TK1/APOBEC3G/APOBEC3C/UMPS/ERH/NME4/DCTPP1/NME1/SLC19A3	19
GO:0042092	type 2 immune response	11/2053	36/18722	0.001191997522456	0.00757551036532446	CD74/CD86/CCR2/STAT6/NLRP3/IL27RA/RARA/RSAD2/BCL6/GATA3/IL18	11
GO:0097696	receptor signaling pathway via STAT	34/2053	181/18722	0.00119467236865652	0.00757551036532446	PTPRC/CSF1R/TGFB1/LYN/IL10RA/CD300A/JAK2/TNF/STAT1/CCR2/SOCS3/JAK1/STAT6/NOTCH1/PARP9/IL6R/PTK2B/SH2B3/HAMP/STAT5A/AKR1B1/STAT2/ISL1/SUZ12/STAT3/HDAC2/IL6ST/HCLS1/CSH1/PARP14/CENPJ/PWP1/IL18/PPARG	34
GO:0002377	immunoglobulin production	39/2053	216/18722	0.00119682033553837	0.00757551036532446	HLA-DPA1/HLA-DPB1/HLA-DRA/PTPRC/HLA-DRB1/HLA-DMA/HLA-DQB1/HLA-DMB/HLA-DQA1/TGFB1/SAMHD1/CD86/HLA-DQA2/B2M/HLA-E/HLA-DRB5/TNF/HSPD1/GAPT/SASH3/PRKDC/BTK/STAT6/IL27RA/UNG/BCL6/PHB2/MSH2/MSH6/CTNNBL1/PHB/ERCC1/RNF8/RIF1/TFRC/POLQ/EXO1/PKN1/DNAJB9	39
GO:0008652	cellular amino acid biosynthetic process	18/2053	76/18722	0.00119693063772126	0.00757551036532446	SDS/DPYD/GLUL/DHFR/SDSL/ADI1/ALDH1A1/MTAP/OAT/ASS1/PARK7/PYCR2/PLOD2/SHMT1/ASNSD1/MTR/SLC1A3/ENOPH1	18
GO:0009123	nucleoside monophosphate metabolic process	18/2053	76/18722	0.00119693063772126	0.00757551036532446	TYMP/DUT/UPP1/TYMS/DPYD/PAICS/DTYMK/TK1/UMPS/PNP/GMPS/ADK/IMPDH2/DLG1/MPP1/AMPD3/DNPH1/PPAT	18
GO:0032720	negative regulation of tumor necrosis factor production	18/2053	76/18722	0.00119693063772126	0.00757551036532446	TSPO/LGALS9/HAVCR2/LILRB1/TNFAIP3/IRAK3/TLR4/GSTP1/CLEC4A/ARRB2/GPNMB/IL27RA/PTPN6/RARA/TREM2/CD33/SIRPA/ACP5	18
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	18/2053	76/18722	0.00119693063772126	0.00757551036532446	CD74/CD44/PYCARD/HINT1/PERP/IFI16/RPS7/DDIT4/MSH2/UBB/PMAIP1/PHLDA3/TRIAP1/BRCA2/CDKN1A/ING2/E2F1/TMEM109	18
GO:0002548	monocyte chemotaxis	17/2053	70/18722	0.00120451882051997	0.00761550360708093	AIF1/CCL3L3/CCL3/CCL4/LYN/S100A12/DUSP1/HMGB1/CCR1/CCR2/CXCL10/LGALS3/PLA2G7/IL6R/FLT1/CX3CR1/RPS19	17
GO:0048024	regulation of mRNA splicing, via spliceosome	22/2053	101/18722	0.00120806289201603	0.00762987089694333	CELF2/SRSF2/MBNL3/NPM1/HNRNPA1/HSPA8/C1QBP/SF1/PRDX6/RBM39/MAGOH/SRSF10/SRPK1/NCL/MBNL1/SRSF7/RBMX/TRA2B/SNRNP70/TIA1/PRPF19/SRSF4	22
GO:0046700	heterocycle catabolic process	70/2053	445/18722	0.0012100435147829	0.00763434394184792	VIM/SLC11A1/APOBEC3A/TYMP/TNFRSF1B/ZFP36/SAMHD1/ZFP36L2/OAS2/DUT/UPP1/HINT1/HMOX1/ISG20/KYNU/RNASE6/DPYD/FEN1/FUS/CARHSP1/PABPC1/RNASET2/UNG/QPRT/IL4I1/LIN28B/ZFP36L1/NPM1/CDA/HNRNPR/ENTPD1/PDE4A/SERBP1/BTG2/EXOSC8/APOBEC3G/LSM2/NUDT8/APOBEC3C/RNASEH2A/LSM4/SLIRP/LSM5/NUDT15/HNRNPD/UPF3A/PNP/MAGOHB/LSM7/MYD88/MAGOH/KHSRP/SND1/HNRNPA0/DNASE1L1/NUDT4/NUDT5/APEX1/HSPA1A/DCTPP1/AGO2/AMPD3/SMPDL3A/VCP/LRPPRC/DNPH1/E2F1/MRTO4/YBX1/MAPK14	70
GO:0030048	actin filament-based movement	26/2053	127/18722	0.00121390907258092	0.00765068743223271	FLNA/WAS/WIPF1/MYO1F/MYO1G/SYNE2/MYH10/DSP/KCNQ1/EMP2/DSG2/GJA1/CAMK2D/KCNE3/GJA5/DSC2/MYL6/MYO1C/FNBP1L/WASF2/SLC9A1/DLG1/AKAP9/MYO5A/ACTN4/MYO7A	26
GO:0001562	response to protozoan	9/2053	26/18722	0.0012351580885213	0.00776015552997675	SLC11A1/CLEC7A/GBP4/GBP2/IRF8/LYST/HRAS/CCDC88B/MYD88	9
GO:1900017	positive regulation of cytokine production involved in inflammatory response	9/2053	26/18722	0.0012351580885213	0.00776015552997675	CLEC7A/GPSM3/GBP5/TNF/TLR4/TLR6/STAT3/MYD88/IL17RA	9
GO:1904376	negative regulation of protein localization to cell periphery	9/2053	26/18722	0.0012351580885213	0.00776015552997675	TGFB1/ABI3/GBP1/CSK/GOPC/RHOQ/NUMB/PICALM/AP2M1	9
GO:0007595	lactation	13/2053	47/18722	0.00124372240734205	0.00777246437445975	OAS2/VEGFA/CCND1/STAT5A/HK2/SLC29A1/CDO1/UMPS/VDR/NCOR2/MTX1/NME1/PPAT	13
GO:0051972	regulation of telomerase activity	13/2053	47/18722	0.00124372240734205	0.00777246437445975	KLF4/HSP90AA1/HSP90AB1/PKIB/HNRNPD/TCP1/CCT2/XRCC5/PNKP/HNRNPA2B1/CCT4/AURKB/MAP3K4	13
GO:0001782	B cell homeostasis	10/2053	31/18722	0.00124488971064264	0.00777246437445975	CD74/TNFSF13B/NCKAP1L/LYN/MEF2C/DOCK10/TNFAIP3/GAPT/DOCK11/PKN1	10
GO:0002230	positive regulation of defense response to virus by host	10/2053	31/18722	0.00124488971064264	0.00777246437445975	PYCARD/LILRB1/STAT1/HSP90AA1/PARP9/AIM2/APOBEC3G/DTX3L/EIF2AK4/DDX58	10
GO:0044819	mitotic G1/S transition checkpoint signaling	10/2053	31/18722	0.00124488971064264	0.00777246437445975	PRKDC/PLK3/CCND1/RPA2/TRIAP1/SOX4/GTSE1/CDKN1A/CDK2/PLK2	10
GO:0046386	deoxyribose phosphate catabolic process	10/2053	31/18722	0.00124488971064264	0.00777246437445975	TYMP/SAMHD1/DUT/UPP1/DPYD/UNG/NUDT15/PNP/DCTPP1/DNPH1	10
GO:0032355	response to estradiol	28/2053	141/18722	0.00131513854137055	0.0082025272850554	TXNIP/TGFB1/DUSP1/EGFR/PCNA/GSTP1/RARA/BMP7/NR2F2/CALR/CCND1/EZH2/GJA1/HPGD/SLC6A4/FAM210B/CCNA2/STAT3/HNRNPD/ASS1/NCOR2/BAD/RBBP8/PTN/MMP15/DDX18/MBD2/MBD3	28
GO:0051438	regulation of ubiquitin-protein transferase activity	14/2053	53/18722	0.00134009912553713	0.00834952726191356	RPS7/RPL5/RPL37/RPL23/MAD2L1/UBE2C/FBXO5/UBE2S/RPS2/BAG2/DTX3L/PARK7/RPS20/UBE2N	14
GO:0009200	deoxyribonucleoside triphosphate metabolic process	7/2053	17/18722	0.00135531696568451	0.00837477012781365	SAMHD1/DUT/TYMS/DTYMK/NUDT15/ADK/DCTPP1	7
GO:0010934	macrophage cytokine production	7/2053	17/18722	0.00135531696568451	0.00837477012781365	LAPTM5/CD74/TGFB1/LILRB1/IRAK3/TLR4/CD36	7
GO:0010935	regulation of macrophage cytokine production	7/2053	17/18722	0.00135531696568451	0.00837477012781365	LAPTM5/CD74/TGFB1/LILRB1/IRAK3/TLR4/CD36	7
GO:0032604	granulocyte macrophage colony-stimulating factor production	7/2053	17/18722	0.00135531696568451	0.00837477012781365	CD84/IL1B/LILRA2/SYK/ISL1/DDX58/IL18	7
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	7/2053	17/18722	0.00135531696568451	0.00837477012781365	CD84/IL1B/LILRA2/SYK/ISL1/DDX58/IL18	7
GO:0060263	regulation of respiratory burst	7/2053	17/18722	0.00135531696568451	0.00837477012781365	NCF1/CLEC7A/RAC2/GRN/CAMK1D/RPS19/INSR	7
GO:0097067	cellular response to thyroid hormone stimulus	7/2053	17/18722	0.00135531696568451	0.00837477012781365	CTSS/CTSB/LMO2/CTSL/CTSH/RDX/GCLM	7
GO:2000811	negative regulation of anoikis	7/2053	17/18722	0.00135531696568451	0.00837477012781365	ITGA5/ITGB1/NOTCH1/PDK4/MCL1/TLE1/PTK2	7
GO:0031397	negative regulation of protein ubiquitination	19/2053	83/18722	0.00136948307416333	0.00844491104314487	TSPO/ISG15/TNFAIP3/ARRB2/RPS7/RPS3/RPL5/PPIA/RPL37/RPL23/MAD2L1/CHP1/FBXO5/SOX4/BAG2/DTX3L/PARK7/HSPA1A/RPS20	19
GO:1901292	nucleoside phosphate catabolic process	19/2053	83/18722	0.00136948307416333	0.00844491104314487	TYMP/SAMHD1/DUT/UPP1/HINT1/DPYD/UNG/ENTPD1/PDE4A/NUDT8/NUDT15/PNP/NUDT4/NUDT5/DCTPP1/AMPD3/SMPDL3A/VCP/DNPH1	19
GO:0046596	regulation of viral entry into host cell	12/2053	42/18722	0.00139305975891955	0.00856389196057101	HLA-DRB1/LGALS1/CD74/FCN1/IFITM2/LGALS9/TRIM22/IFITM3/CD4/P4HB/CIITA/TRIM38	12
GO:0072595	maintenance of protein localization in organelle	12/2053	42/18722	0.00139305975891955	0.00856389196057101	TSPO/HSPA5/HK2/GJA1/GPAA1/BARD1/TXN/ARL2/CHCHD10/SP100/PARK7/KDELR2	12
GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	12/2053	42/18722	0.00139305975891955	0.00856389196057101	SPI1/TGFB1/FOS/KLF4/TNF/STAT3/GATA3/KLF5/GNL3/TEAD1/JUN/PPARG	12
GO:0048010	vascular endothelial growth factor receptor signaling pathway	15/2053	59/18722	0.00139820955319388	0.00857797271898084	VEGFA/ITGA5/IL1B/HHEX/VAV1/PTK2B/PRKCB/FLT1/NRP1/MAPKAPK3/EPN2/BCAR1/FOXC1/PTK2/MAPK14	15
GO:0090303	positive regulation of wound healing	15/2053	59/18722	0.00139820955319388	0.00857797271898084	CXCR4/CLEC7A/HMGB1/PRDX2/CD36/CLDN4/ITGB1/HPSE/HBEGF/KANK1/FERMT1/HRAS/PLPP3/FERMT2/PTK2	15
GO:0000281	mitotic cytokinesis	17/2053	71/18722	0.00142467595836108	0.00873141547514453	STMN1/MYH10/NUSAP1/RASA1/RHOA/KIF23/CKAP2/ANK3/ANLN/KIF20B/SPTBN1/ECT2/TTC19/RHOB/CHMP4C/KIF4A/RTKN	17
GO:0009895	negative regulation of catabolic process	53/2053	320/18722	0.0014561168223636	0.00891500095324652	TSPO/TIMP1/SLC11A1/ZFP36/FLNA/SORL1/CST3/IL10RA/EGFR/LRRK2/FBP1/TNF/IRAK3/IL1B/HMOX1/NAMPT/RPS7/MET/FUS/PABPC1/QSOX1/HSP90AB1/RPL5/TIMP2/TIMP3/TREM2/RPL23/MAD2L1/DDIT4/PBK/MCL1/APOC1/SLIRP/STAT3/HNRNPD/SMARCC1/SDCBP/MYD88/ATRAID/EFNA1/USP14/SVIP/PHB/HNRNPA0/PARK7/SNRNP70/PTPN3/LRPPRC/E2F1/EIF4G1/YBX1/MAPK14/ALAD	53
GO:0051304	chromosome separation	21/2053	96/18722	0.00145862626038789	0.00892126153142437	DUSP1/TOP2A/CENPF/ZWINT/MAD2L1/CDC6/ANAPC11/UBE2C/CDT1/FBXO5/RAD21/BUB3/PLSCR1/TPR/NDC80/TTK/TOP2B/AURKB/LCMT1/BUB1B/KNTC1	21
GO:0090130	tissue migration	59/2053	365/18722	0.00148101932593396	0.00904899791813008	TMSB4X/ZEB2/TGFB1/MEF2C/HMGB1/GPX1/KLF4/VEGFA/TNF/SERPINF1/HMOX1/GRN/MET/GLIPR2/NRP2/CTSH/VASH1/GLUL/ITGB1/DPP4/SEMA4A/NOTCH1/NR2F2/CALR/TNFSF12/PTK2B/NR4A1/EMP2/FSTL1/STAT5A/RRAS/ID1/HBEGF/KANK1/TACSTD2/FERMT1/AMOT/NRP1/RHOA/CIB1/MARVELD3/RGCC/GATA3/EPHB4/PLPP3/ANLN/EFNA1/RAB25/ANXA3/PFN1/SP100/BCAR1/CORO1C/RHOB/PLK2/PTN/PTK2/PKN1/PPARG	59
GO:0034112	positive regulation of homotypic cell-cell adhesion	6/2053	13/18722	0.00149523530466874	0.00910803231270296	LGALS1/PLAUR/JAK2/JAK1/IL6ST/ANK3	6
GO:0042769	DNA damage response, detection of DNA damage	6/2053	13/18722	0.00149523530466874	0.00910803231270296	PARP1/RPS3/MRPS26/USP1/SOX4/PNKP	6
GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	6/2053	13/18722	0.00149523530466874	0.00910803231270296	SKIL/TIMP3/PMAIP1/ATF3/STK4/PEA15	6
GO:0007160	cell-matrix adhesion	41/2053	233/18722	0.00151957018512697	0.00924687739428177	ITGB2/CD44/FERMT3/FN1/ITGAL/VEGFA/CD36/ITGA4/PARVG/DAG1/ITGB1/ITGB4/BCL6/HPSE/BCAM/PTK2B/EMP2/SIGLEC1/RRAS/RASA1/S100A10/LIMS1/FERMT1/PLEKHA2/NRP1/RHOA/CIB1/ITGB5/ZYX/ITGAV/JAM3/CD63/CDK6/CDKN2A/FERMT2/SLC9A1/VCL/CORO1C/SGCE/PTK2/TRIP6	41
GO:0035304	regulation of protein dephosphorylation	20/2053	90/18722	0.00152872459123041	0.00929315860930343	PTPRC/TGFB1/NCKAP1L/LILRB2/CD300A/JAK2/HSP90B1/TNF/HSP90AB1/PPIA/LGALS3/CD33/SLC39A10/GNAI2/CALM2/YWHAE/MASTL/FKBP1A/PPP1R15A/ENSA	20
GO:0007259	receptor signaling pathway via JAK-STAT	32/2053	170/18722	0.00158066430012967	0.00959917591171863	PTPRC/CSF1R/LYN/IL10RA/CD300A/JAK2/TNF/STAT1/CCR2/SOCS3/JAK1/STAT6/NOTCH1/PARP9/IL6R/PTK2B/SH2B3/HAMP/STAT5A/AKR1B1/STAT2/ISL1/SUZ12/STAT3/HDAC2/IL6ST/HCLS1/CSH1/PARP14/CENPJ/PWP1/IL18	32
GO:0071453	cellular response to oxygen levels	33/2053	177/18722	0.00159161908530148	0.00965592973893719	CYBB/SLC8A1/VEGFA/P4HB/HMOX1/NAMPT/PLK3/CARD16/MALAT1/BMP7/NOTCH1/ZFP36L1/TREM2/ADAM8/ICAM1/HILPDA/SLC29A1/BNIP3L/PHB2/KCNMB1/PMAIP1/EPAS1/CCNA2/RGCC/CHCHD2/BACH1/SLC9A1/BAD/BNIP3/PTN/LMNA/E2F1/NDRG1	33
GO:1903305	regulation of regulated secretory pathway	27/2053	136/18722	0.00159417458551004	0.00966166415460633	ITGB2/HLA-F/SPI1/LGALS9/NCKAP1L/CD84/LYN/CD300A/RAC2/FGR/LRRK2/ITGAM/PTAFR/HMOX1/STXBP2/CCR2/ADGRE2/PRAM1/SYK/NOTCH1/PRKCB/GNAI2/SYT7/SNX4/RAB3D/RAP1A/CHRNA5	27
GO:0050860	negative regulation of T cell receptor signaling pathway	8/2053	22/18722	0.0016013859969453	0.00968580240087885	LAPTM5/LILRB4/GBP1/PTPN6/LGALS3/PAWR/PHPT1/EZR	8
GO:2000773	negative regulation of cellular senescence	8/2053	22/18722	0.0016013859969453	0.00968580240087885	NAMPT/PRKDC/BCL6/FBXO5/CDK6/RBL1/PLK2/YBX1	8
GO:0030010	establishment of cell polarity	28/2053	143/18722	0.00164099120420098	0.00989404483995434	MSN/DOCK2/HSP90AA1/HSP90AB1/ITGB1/MAD2L1/PTK2B/WEE1/GJA1/KANK1/FAT1/FERMT1/AMOT/RHOA/FRMD4A/PARD3/CYTH1/GATA3/JAM3/KIF20B/NDC80/TCIRG1/GPSM2/PTK2/AMOTL2/MPP7/AMOTL1/DYNLT1	28
GO:0030500	regulation of bone mineralization	18/2053	78/18722	0.00164241144343242	0.00989404483995434	SRGN/CCL3/ISG15/TGFB1/SLC8A1/MEF2C/FBN2/ALOX5/CCR1/BMP7/ATP2B1/PTK2B/NOTUM/P2RX7/BMP2K/TFAP2A/ATRAID/PTN	18
GO:0043297	apical junction assembly	18/2053	78/18722	0.00164241144343242	0.00989404483995434	PECAM1/MTDH/TNF/GPBAR1/CLDN4/CLDN7/GJA1/RHOA/MARVELD3/PARD3/ARL2/DLG5/MYO1C/TJP1/VCL/ECT2/DLG1/MPP7	18
GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	18/2053	78/18722	0.00164241144343242	0.00989404483995434	TSPO/LGALS9/HAVCR2/LILRB1/TNFAIP3/IRAK3/TLR4/GSTP1/CLEC4A/ARRB2/GPNMB/IL27RA/PTPN6/RARA/TREM2/CD33/SIRPA/ACP5	18
GO:0003018	vascular process in circulatory system	45/2053	263/18722	0.00166019365922663	0.00999047977734542	TGFB1/SLC2A3/SLC8A1/GPX1/EGFR/SOD2/VEGFA/LRP2/KLF2/CD36/SLC2A1/DOCK4/SLC38A1/SOD1/TBXAS1/ATP2B1/ICAM1/SLC29A1/GJA1/KCNMB1/HRH2/SLC6A6/GJA5/SLC6A4/ADRB1/SCPEP1/RHOA/FABP5/SLC1A5/SLC16A12/SLC16A1/GCLM/SLC19A1/TJP1/FERMT2/SOD3/RGS2/SLC13A3/GCH1/SLC44A1/YES1/TFRC/FOXC1/INSR/SLC1A3	45
GO:0070167	regulation of biomineral tissue development	21/2053	97/18722	0.00167301380248676	0.00999047977734542	SRGN/CCL3/ISG15/TGFB1/SLC8A1/MEF2C/FBN2/ALOX5/CCR1/CEBPB/BMP7/NOTCH1/ATP2B1/PTK2B/NOTUM/P2RX7/BMP2K/TFAP2A/FBXO5/ATRAID/PTN	21
GO:0002719	negative regulation of cytokine production involved in immune response	9/2053	27/18722	0.00167434731133562	0.00999047977734542	BST2/HLA-F/TGFB1/LILRB1/LILRB4/TNF/IRAK3/HMOX1/BCL6	9
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	9/2053	27/18722	0.00167434731133562	0.00999047977734542	APP/CDK1/CCND1/DTL/RAD51C/FBXO5/CDK4/BRD4/PBX1	9
GO:0036037	CD8-positive, alpha-beta T cell activation	9/2053	27/18722	0.00167434731133562	0.00999047977734542	HLA-A/NCKAP1L/HLA-E/LILRB1/LILRB4/CLEC4A/RUNX1/IRF1/RUNX3	9
GO:0071624	positive regulation of granulocyte chemotaxis	9/2053	27/18722	0.00167434731133562	0.00999047977734542	CD74/NCKAP1L/C5AR1/C3AR1/RAC2/CAMK1D/CXCL8/C1QBP/MDK	9
GO:0002534	cytokine production involved in inflammatory response	17/2053	72/18722	0.00167785435972521	0.00999047977734542	CLEC7A/GPSM3/PYCARD/LILRB4/GBP5/ALOX5/TNF/TLR4/TLR6/TREM2/EZH2/STAT3/SIRPA/MYD88/IL17RA/CHID1/MAPK14	17
GO:1900015	regulation of cytokine production involved in inflammatory response	17/2053	72/18722	0.00167785435972521	0.00999047977734542	CLEC7A/GPSM3/PYCARD/LILRB4/GBP5/ALOX5/TNF/TLR4/TLR6/TREM2/EZH2/STAT3/SIRPA/MYD88/IL17RA/CHID1/MAPK14	17
GO:0002712	regulation of B cell mediated immunity	15/2053	60/18722	0.00167840060259403	0.00999047977734542	PTPRC/TGFB1/HLA-E/TNF/C3/BTK/STAT6/CD46/IL27RA/PTPN6/BCL6/TREM2/MSH2/RIF1/TFRC	15
GO:0002889	regulation of immunoglobulin mediated immune response	15/2053	60/18722	0.00167840060259403	0.00999047977734542	PTPRC/TGFB1/HLA-E/TNF/C3/BTK/STAT6/CD46/IL27RA/PTPN6/BCL6/TREM2/MSH2/RIF1/TFRC	15
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	15/2053	60/18722	0.00167840060259403	0.00999047977734542	CLSPN/CDK1/CDC6/BRCA1/NAE1/DTL/CHEK1/RAD21/TOPBP1/BLM/FOXO4/CDKN1A/AURKB/CHMP4C/BRCC3	15
GO:0031102	neuron projection regeneration	15/2053	60/18722	0.00167840060259403	0.00999047977734542	TSPO/FLNA/KLF4/SPP1/JAK2/GRN/DAG1/NREP/DHFR/ISL1/FOLR1/JAM3/PTPRF/PTN/MTR	15
GO:0006303	double-strand break repair via nonhomologous end joining	16/2053	66/18722	0.00169203192574424	0.0100516748064015	HMGB1/HMGB2/DEK/PRKDC/PARP9/PSMD14/XRCC5/PNKP/DTX3L/XRCC6/POLA1/ERCC1/RNF8/RIF1/POLQ/PRPF19	16
GO:0032715	negative regulation of interleukin-6 production	16/2053	66/18722	0.00169203192574424	0.0100516748064015	NCKAP1L/CD84/HAVCR2/LILRB4/KLF2/TNF/TNFAIP3/IRAK3/TLR4/ARRB2/IL27RA/PTPN6/CSK/NLRP12/SIRPA/INPP5D	16
GO:0044270	cellular nitrogen compound catabolic process	70/2053	451/18722	0.00172604030942728	0.0102435626672242	VIM/SLC11A1/APOBEC3A/TYMP/TNFRSF1B/ZFP36/SAMHD1/ZFP36L2/OAS2/DUT/UPP1/HINT1/HMOX1/ISG20/KYNU/RNASE6/DPYD/FEN1/FUS/CARHSP1/PABPC1/RNASET2/UNG/QPRT/IL4I1/LIN28B/ZFP36L1/NPM1/CDA/HNRNPR/ENTPD1/PDE4A/SERBP1/BTG2/EXOSC8/APOBEC3G/LSM2/NUDT8/APOBEC3C/RNASEH2A/LSM4/SLIRP/LSM5/NUDT15/HNRNPD/UPF3A/PNP/MAGOHB/LSM7/MYD88/MAGOH/KHSRP/SND1/HNRNPA0/DNASE1L1/NUDT4/NUDT5/APEX1/HSPA1A/DCTPP1/AGO2/AMPD3/SMPDL3A/VCP/LRPPRC/DNPH1/E2F1/MRTO4/YBX1/MAPK14	70
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	12/2053	43/18722	0.0017422564238101	0.010319386518125	CD74/CD44/PYCARD/IFI16/DDIT4/MSH2/PHLDA3/TRIAP1/BRCA2/CDKN1A/ING2/TMEM109	12
GO:0071604	transforming growth factor beta production	12/2053	43/18722	0.0017422564238101	0.010319386518125	TYROBP/LGALS9/LILRB1/FN1/CD24/CD46/HSP90AB1/FERMT1/LTBP1/ITGAV/CD2AP/ITGB8	12
GO:0050714	positive regulation of protein secretion	27/2053	137/18722	0.00178238623008021	0.0105466640833148	HLA-DRB1/TGFB1/TLR2/EGFR/JAK2/TLR4/MYH10/WLS/GLUL/MPC2/SERP1/PPIA/TREM2/ADAM8/CD33/GJA1/TRPM2/ISL1/FRMD4A/SOX4/ACSL4/KCNN4/PHPT1/EZR/BAD/CD2AP/TM7SF3	27
GO:0019439	aromatic compound catabolic process	72/2053	467/18722	0.00178936479775726	0.0105775258980725	VIM/SLC11A1/APOBEC3A/TYMP/TNFRSF1B/ZFP36/SAMHD1/ZFP36L2/OAS2/DUT/UPP1/HINT1/HMOX1/ISG20/KYNU/RNASE6/DPYD/FEN1/FUS/CARHSP1/PABPC1/RNASET2/UNG/IL4I1/LIN28B/ZFP36L1/NPM1/CDA/COMT/HNRNPR/ENTPD1/PDE4A/SERBP1/BTG2/EXOSC8/PON2/APOBEC3G/LSM2/NUDT8/APOBEC3C/RNASEH2A/LSM4/SLIRP/LSM5/NUDT15/HNRNPD/UPF3A/PNP/MAGOHB/LSM7/MYD88/MAGOH/KHSRP/SND1/HNRNPA0/DNASE1L1/NUDT4/NUDT5/APEX1/HSPA1A/QDPR/DCTPP1/AGO2/AMPD3/SMPDL3A/VCP/LRPPRC/DNPH1/E2F1/MRTO4/YBX1/MAPK14	72
GO:0106106	cold-induced thermogenesis	28/2053	144/18722	0.00182848721793207	0.0107875352090387	CXCR4/PLAC8/UCP2/JAK2/VEGFA/TLR4/CD36/G0S2/CEBPB/GNAS/CCR2/STAT6/SYK/NOTCH1/TRPV2/ID1/GJA1/ALDH1A1/EPAS1/ADRB1/FABP5/RHEB/HADH/FH/LGR4/IGF1R/KDM6B/IL18	28
GO:0120161	regulation of cold-induced thermogenesis	28/2053	144/18722	0.00182848721793207	0.0107875352090387	CXCR4/PLAC8/UCP2/JAK2/VEGFA/TLR4/CD36/G0S2/CEBPB/GNAS/CCR2/STAT6/SYK/NOTCH1/TRPV2/ID1/GJA1/ALDH1A1/EPAS1/ADRB1/FABP5/RHEB/HADH/FH/LGR4/IGF1R/KDM6B/IL18	28
GO:0040013	negative regulation of locomotion	62/2053	391/18722	0.00183656766244797	0.010824563825823	AIF1/TIMP1/CD74/BST2/ARHGDIB/TGFB1/WAS/MEF2C/FBLN1/CD300A/DUSP1/HMGB1/KLF4/SPINT2/TCAF1/CDH1/TNF/SERPINF1/GSTP1/HMOX1/ADGRG1/PTGER4/CNN2/VASH1/DAG1/IL27RA/DPP4/ENG/SEMA4A/NOTCH1/NR2F2/CALR/MCTP1/ARHGAP4/LDLRAD4/SEMA6A/RRAS/IDH2/GJA1/CX3CR1/KANK1/TACSTD2/TRIB1/NRP1/RHOA/MARVELD3/STAT3/RIN3/RGCC/GATA3/DLG5/SEMA6D/ABHD2/SP100/APEX1/VCL/CORO1C/RHOB/PTN/CCDC125/PTPRU/PPARG	62
GO:0001913	T cell mediated cytotoxicity	13/2053	49/18722	0.00188523564647156	0.0111005042971829	HLA-B/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/HLA-F/NCKAP1L/B2M/HLA-E/LILRB1/CTSH/CD1D/EMP2	13
GO:0002637	regulation of immunoglobulin production	17/2053	73/18722	0.00196783332289927	0.0115641527300643	PTPRC/TGFB1/CD86/HLA-E/TNF/SASH3/PRKDC/STAT6/IL27RA/BCL6/PHB2/MSH2/PHB/RIF1/TFRC/PKN1/DNAJB9	17
GO:0042274	ribosomal small subunit biogenesis	17/2053	73/18722	0.00196783332289927	0.0115641527300643	RPS21/RPS5/RPS17/RPS7/RPSA/RPS27/PRKDC/RPS16/RPS14/NPM1/RPS19/RPS6/RPS8/SNU13/XRCC5/RPS25/BMS1	17
GO:0042130	negative regulation of T cell proliferation	16/2053	67/18722	0.00200062581068071	0.0117338757224675	HLA-DRB1/LGALS9/CD86/LILRB2/HAVCR2/LILRB1/LILRB4/TNFRSF14/CEBPB/GPNMB/PTPN6/IL4I1/SPN/PAWR/DLG5/DLG1	16
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	16/2053	67/18722	0.00200062581068071	0.0117338757224675	HLA-DRA/HLA-DRB1/LGALS9/NCKAP1L/CD86/CD83/HMGB1/RUNX1/SASH3/NLRP3/RARA/BCL6/RUNX3/GATA3/NFKBIZ/IL18	16
GO:2000401	regulation of lymphocyte migration	15/2053	61/18722	0.00200395609121039	0.0117419302219359	AIF1/CCL3/MSN/CCL4/PYCARD/TNFRSF14/APP/ITGA4/CCR2/CXCL10/IL27RA/ADAM8/PTK2B/SPN/RHOA	15
GO:0051782	negative regulation of cell division	7/2053	18/18722	0.0020094070035682	0.0117509181495216	TXNIP/ORC6/ASPM/BLM/AURKB/CHMP4C/E2F7	7
GO:1903209	positive regulation of oxidative stress-induced cell death	7/2053	18/18722	0.0020094070035682	0.0117509181495216	TLR4/TLR6/SOD1/MCL1/PAWR/TRPM2/PARK7	7
GO:0045446	endothelial cell differentiation	24/2053	118/18722	0.00201143680099698	0.0117513347672657	CXCR4/MSN/PECAM1/GPX1/VEGFA/TNF/IL1B/MYADM/MET/NOTCH1/NR2F2/FSTL1/ICAM1/ID1/BTG1/RDX/NRP1/MYD88/TJP1/RAP1A/VCL/EZR/KDM6B/PTN	24
GO:0060562	epithelial tube morphogenesis	53/2053	325/18722	0.00205916585930843	0.0120184777780648	CXCR4/CSF1R/TGFB1/MEF2C/SPINT1/SPINT2/VEGFA/LRP2/TNF/VASP/RPS7/MAGED1/CXCL10/MET/CTSH/CTSZ/DAG1/ITGAX/RARA/BMP7/LAMA5/ENG/NOTCH1/LMO4/LGR5/PHB2/TACSTD2/NRP1/RHOA/NOTCH2/SOX4/AHI1/VDR/GATA3/DLG5/FOLR1/PBX1/LRP5/COL4A1/LGR4/KIF20B/YAP1/PFN1/DLG1/RHOB/LUZP1/GLI3/STK4/MDK/TBX3/IRX2/COBL/GPC3	53
GO:1902904	negative regulation of supramolecular fiber organization	31/2053	166/18722	0.00210888505224388	0.0122967058439876	TMSB4X/GMFG/CORO1A/CAPG/WAS/TMSB10/STMN1/MYADM/PFDN5/MET/TREM2/KANK1/TACSTD2/HSPA8/RDX/CIB1/TPX2/KANK4/CKAP2/TWF2/SCIN/MID1IP1/SPTBN1/TJP1/WASF2/PFN1/EPS8/ARHGEF2/LIMA1/PFDN1/TRIOBP	31
GO:0002335	mature B cell differentiation	10/2053	33/18722	0.002118210847047	0.0123271242311174	LGALS1/SPI1/DOCK10/IRF8/LFNG/PTK2B/GPR183/MFNG/NOTCH2/DOCK11	10
GO:0045648	positive regulation of erythrocyte differentiation	10/2053	33/18722	0.002118210847047	0.0123271242311174	ISG15/NCKAP1L/HMGB2/STAT1/PRKDC/FAM210B/STAT3/INPP5D/HSPA1A/MAPK14	10
GO:0043087	regulation of GTPase activity	56/2053	348/18722	0.00212981249210449	0.0123826307680494	CCL3L3/CCL3/CCL4/PYCARD/GPR65/STMN1/LRRK2/DOCK10/ITGA6/PLXNC1/FGD2/ADAP2/ARRB2/RGS1/TGM2/MET/RGS10/PREX1/SOD1/ITGB1/BCL6/VAV1/PTK2B/ARHGAP25/ICAM1/GMIP/IQGAP2/RASA1/ARHGAP27/EZH2/S100A10/LIMS1/HRAS/AMOT/RDX/ADRB1/RASGRP2/ABR/ARL2/DOCK9/FGD3/RAP1A/NET1/FERMT2/RHOG/SYDE2/ECT2/VAV3/CORO1C/FGD4/EIF5/DOCK11/PICALM/PTK2/CCDC125/DYNLT1	56
GO:0006325	chromatin organization	64/2053	409/18722	0.00217510653431143	0.0126337262399502	NASP/HMGB1/ACTB/HMGB2/HELLS/DEK/RBBP7/DNAJC9/CENPW/MKI67/DNMT1/NUCKS1/ATAD2/SUPT16H/IKZF1/NPM1/ASF1B/HMGN2/SET/EZH2/NAP1L1/HMGN3/RBBP4/MCM2/HAT1/CBX3/BAZ1B/ITGB3BP/SMARCA1/HDAC2/HMGA1/SMARCC1/GATA3/CBX4/BRD4/CHD9/SSRP1/CHAF1A/BAZ2B/TPR/POLE3/SMARCA2/HMGN1/SRPK1/NUDT5/RBL1/MIS18A/KMT2E/HIRIP3/PHF21A/RERE/RNF8/ING2/TLK1/RCCD1/TRIM28/NAP1L4/KDM6B/ACTL6A/MBD2/HLTF/ACTR6/MBD3/SMARCA5	64
GO:0110149	regulation of biomineralization	21/2053	99/18722	0.00218293997050228	0.0126669630783498	SRGN/CCL3/ISG15/TGFB1/SLC8A1/MEF2C/FBN2/ALOX5/CCR1/CEBPB/BMP7/NOTCH1/ATP2B1/PTK2B/NOTUM/P2RX7/BMP2K/TFAP2A/FBXO5/ATRAID/PTN	21
GO:0009162	deoxyribonucleoside monophosphate metabolic process	8/2053	23/18722	0.00222181778906888	0.0128552620389714	TYMP/DUT/UPP1/TYMS/DPYD/TK1/PNP/DNPH1	8
GO:0045662	negative regulation of myoblast differentiation	8/2053	23/18722	0.00222181778906888	0.0128552620389714	TGFB1/TNF/CXCL10/MBNL3/NOTCH1/ID3/TBX3/IL18	8
GO:0050765	negative regulation of phagocytosis	8/2053	23/18722	0.00222181778906888	0.0128552620389714	TLR2/CD300A/HMGB1/CD300LF/CNN2/CSK/SIRPA/PLSCR1	8
GO:0002675	positive regulation of acute inflammatory response	9/2053	28/18722	0.00223022173096708	0.0128666638325024	HLA-E/ALOX5AP/TNF/IL1B/C3/BTK/ADAM8/IL6ST/PARK7	9
GO:0045671	negative regulation of osteoclast differentiation	9/2053	28/18722	0.00223022173096708	0.0128666638325024	CCL3/MAFB/LILRB1/LILRB3/LILRB4/FBN1/TLR4/INPP5D/UBASH3B	9
GO:0090344	negative regulation of cell aging	9/2053	28/18722	0.00223022173096708	0.0128666638325024	NAMPT/PRKDC/BCL6/FBXO5/CDK6/RBL1/PLK2/FOXM1/YBX1	9
GO:0000387	spliceosomal snRNP assembly	13/2053	50/18722	0.00229607448527426	0.0132338587047508	SNRPG/SNRPD1/SNRPB/SNRPF/SNRPE/LSM2/LSM4/SNRPD3/SRSF10/COIL/PRPF8/SNRPD2/PRPF19	13
GO:1901796	regulation of signal transduction by p53 class mediator	20/2053	93/18722	0.00231702066615915	0.0133289779453067	CD74/CD44/SGK1/RPS7/PLK3/RPL5/RPL37/RPL23/NPM1/UBB/CHEK1/PMAIP1/TRIAP1/EEF1E1/SMYD2/TRIM24/KMT5A/ING2/AURKB/RPS20	20
GO:1902807	negative regulation of cell cycle G1/S phase transition	20/2053	93/18722	0.00231702066615915	0.0133289779453067	KLF4/PRKDC/PLK3/GPNMB/CCND1/CTDSPL/WEE1/EZH2/RPA2/TRIAP1/SOX4/BRD7/GTSE1/RBL1/DLG1/CDKN1A/CDK2AP2/CDK2/PLK2/E2F7	20
GO:0071887	leukocyte apoptotic process	22/2053	106/18722	0.00232215910928131	0.0133457420073638	CD74/TSC22D3/LGALS9/LYN/MEF2C/LILRB1/CTSL/IRF7/BTK/LGALS3/PLEKHO2/BCL6/ADAM8/SLC39A10/TCP1/RPS6/EFNA1/CDKN2A/HCLS1/AURKB/GLI3/PKN1	22
GO:0045732	positive regulation of protein catabolic process	40/2053	231/18722	0.00232972787477793	0.0133688130424589	LAPTM5/MSN/TNFRSF1B/SORL1/LRRK2/LRP2/OAZ1/TNF/TNFAIP3/IL1B/PLK3/HSP90AA1/TREM2/TNFSF12/ADAM8/PTK2B/HAMP/PSMC3/GJA1/DTL/TRIB1/DDB1/RDX/BARD1/PSMC1/BAG2/PSMC2/MAGEF1/TMTC3/EZR/HSPA1A/VCP/PLK2/GABARAP/PTK2/PACSIN3/HUWE1/NDUFA13/MYLIP/GPC3	40
GO:1901361	organic cyclic compound catabolic process	75/2053	495/18722	0.002330629740402	0.0133688130424589	VIM/SLC11A1/APOBEC3A/TYMP/TNFRSF1B/ZFP36/SAMHD1/ZFP36L2/OAS2/DUT/SPP1/UPP1/HINT1/HMOX1/ISG20/KYNU/RNASE6/DPYD/FEN1/FUS/CARHSP1/PABPC1/RNASET2/UNG/QPRT/IL4I1/LIN28B/ZFP36L1/NPM1/CDA/COMT/HNRNPR/ENTPD1/PDE4A/SERBP1/BTG2/EXOSC8/APOBEC3G/LSM2/NUDT8/APOBEC3C/RNASEH2A/LSM4/SLIRP/LSM5/NUDT15/HNRNPD/UPF3A/PNP/MAGOHB/LSM7/MYD88/HSD17B11/MAGOH/KHSRP/SND1/HNRNPA0/DNASE1L1/NUDT4/NUDT5/APEX1/HSPA1A/QDPR/DCTPP1/AGO2/AMPD3/SMPDL3A/STS/VCP/LRPPRC/DNPH1/E2F1/MRTO4/YBX1/MAPK14	75
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	14/2053	56/18722	0.002364852579553	0.0135521637796734	HLA-B/TYROBP/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/HLA-F/SPI1/B2M/HLA-E/ITGAM/CADM1/CD1D/VAV1	14
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	6/2053	14/18722	0.00237519564414528	0.013572546537973	FBLN1/GBP1/KANK1/TACSTD2/CORO1C/ACTN4	6
GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	6/2053	14/18722	0.00237519564414528	0.013572546537973	FBLN1/GBP1/KANK1/TACSTD2/CORO1C/ACTN4	6
GO:1904814	regulation of protein localization to chromosome, telomeric region	6/2053	14/18722	0.00237519564414528	0.013572546537973	TCP1/CCT6A/CCT2/GNL3/CCT4/CCT8	6
GO:0060135	maternal process involved in female pregnancy	15/2053	62/18722	0.00238034038354319	0.0135890031410648	LGALS9/HAVCR2/CTSB/JUNB/SPP1/BSG/NR2F2/CTSV/GJA1/AKR1B1/PRDX3/VDR/RGS2/PTN/PPAT	15
GO:0031668	cellular response to extracellular stimulus	42/2053	246/18722	0.00241939156294161	0.0137988111954844	AIF1/CD68/PTPRC/LYN/ASGR1/FOS/UCP2/UPP1/LRRK2/IFI16/NR4A2/GSTP1/ITGA4/HMOX1/NAMPT/SLC2A1/GLUL/ATP2B1/PDK4/COMT/HSPA5/ICAM1/CTSV/HNRNPA1/HSPA8/PMAIP1/NUDT15/VDR/FOLR1/RALB/TRIM24/EIF2AK4/JUN/CDKN1A/DCTPP1/ATF3/SKP2/PTN/GABARAP/EIF4G1/WIPI2/PRKAG2	42
GO:0001914	regulation of T cell mediated cytotoxicity	11/2053	39/18722	0.00244261266247313	0.0139045749568807	HLA-B/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/HLA-F/NCKAP1L/B2M/HLA-E/LILRB1/CD1D	11
GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	11/2053	39/18722	0.00244261266247313	0.0139045749568807	HLA-DRA/HLA-DRB1/LGALS9/NCKAP1L/CD86/CD83/SASH3/NLRP3/RARA/NFKBIZ/IL18	11
GO:0008380	RNA splicing	67/2053	434/18722	0.00244488776325152	0.0139045749568807	CELF2/SNRPG/SNRPD1/FUS/PABPC1/SNRPB/SNRPF/SRSF2/PSIP1/SNRPE/LGALS3/MBNL3/NPM1/HNRNPR/HNRNPA3/HNRNPA1/HSPA8/LSM2/C1QBP/LSM4/LSM3/SF1/SNRPD3/LSM5/SNRPA1/MAGOHB/TSEN34/PRDX6/CTNNBL1/LSM7/RBM39/MAGOH/KHSRP/SRSF10/SNU13/ESRP1/ZNF326/PNN/HTATSF1/SRPK1/NCL/HNRNPA2B1/RBM17/MBNL1/DDX1/SRSF7/HSPA1A/RBMX/USP39/COIL/TRA2B/SNRNP70/MFAP1/SRSF11/TIA1/SF3A3/PRPF8/LUC7L3/SNRPD2/PRPF19/TTF2/SNRNP25/SNRNP40/WBP11/LSM8/YBX1/SRSF4	67
GO:0031333	negative regulation of protein-containing complex assembly	27/2053	140/18722	0.00246560715754415	0.013988518108846	TMSB4X/CAPG/SORL1/HMGB1/TMSB10/STMN1/MYADM/PTGER4/LMO4/TREM2/HSPA5/LDLRAD4/KANK1/RPL13A/RDX/ISL1/KANK4/TWF2/JAM3/SCIN/SPTBN1/SVIP/PFN1/EPS8/PARK7/LCMT1/TRIOBP	27
GO:0002765	immune response-inhibiting signal transduction	5/2053	10/18722	0.00247363628558093	0.013988518108846	LYN/LILRB2/LILRB1/LILRB4/CD33	5
GO:0031055	chromatin remodeling at centromere	5/2053	10/18722	0.00247363628558093	0.013988518108846	NASP/HELLS/CENPW/ITGB3BP/MIS18A	5
GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	5/2053	10/18722	0.00247363628558093	0.013988518108846	PTPRC/LYN/CSK/PLSCR1/RAP1A	5
GO:1904851	positive regulation of establishment of protein localization to telomere	5/2053	10/18722	0.00247363628558093	0.013988518108846	TCP1/CCT6A/CCT2/CCT4/CCT8	5
GO:2000425	regulation of apoptotic cell clearance	5/2053	10/18722	0.00247363628558093	0.013988518108846	HMGB1/CD300LF/C3/TGM2/TREM2	5
GO:0001763	morphogenesis of a branching structure	35/2053	196/18722	0.00250768333261309	0.0141677024441417	SPINT1/SPINT2/LRRK2/VEGFA/TNF/MAGED1/SOCS3/TGM2/MET/CTSH/CTSZ/DAG1/BMP7/LAMA5/ENG/NOTCH1/PHB2/TACSTD2/NRP1/VDR/DLG5/PBX1/LRP5/GRB2/COL4A1/LGR4/YAP1/DLG1/RERE/GLI3/STK4/MDK/TBX3/PDGFA/GPC3	35
GO:0061138	morphogenesis of a branching epithelium	33/2053	182/18722	0.00254617680762013	0.0143716470796997	SPINT1/SPINT2/VEGFA/TNF/MAGED1/SOCS3/TGM2/MET/CTSH/CTSZ/DAG1/BMP7/LAMA5/ENG/NOTCH1/PHB2/TACSTD2/NRP1/VDR/DLG5/PBX1/LRP5/GRB2/COL4A1/LGR4/YAP1/DLG1/GLI3/STK4/MDK/TBX3/PDGFA/GPC3	33
GO:0048708	astrocyte differentiation	18/2053	81/18722	0.00256793902230931	0.0144808591483608	VIM/S100A8/C5AR1/EGFR/TNF/TLR4/APP/GRN/S100A9/NOTCH1/TREM2/C1QA/STAT3/IL6ST/CDK6/ID2/IFNGR1/PRPF19	18
GO:0051960	regulation of nervous system development	68/2053	443/18722	0.0026308956378759	0.0148219472556389	TSPO/CXCR4/TYMP/TNFRSF1B/TGFB1/LYN/SORL1/B2M/TLR2/FN1/SPINT1/SKIL/EGFR/SPP1/VEGFA/PLXNC1/LRP2/TNF/HMGB2/IL1B/SERPINF1/TGM2/DAG1/ITGAX/MME/RARA/BMP7/SEMA4A/NOTCH1/TREM2/ARHGAP4/TRPV2/SEMA6A/ID1/IDH2/ASPM/EZH2/CX3CR1/NAP1L1/TPBG/ASCL2/NRP1/ACTR2/RHEB/PARD3/HDAC2/GOLGA4/IL6ST/DLG5/TWF2/BHLHE40/SEMA6D/XRCC5/YAP1/OBSL1/DLG1/PRTG/GLI3/ID2/NUMB/MDK/BHLHE41/PTN/PRPF19/E2F1/CLSTN1/XRCC2/DYNLT1	68
GO:0061326	renal tubule development	20/2053	94/18722	0.00264613343019656	0.0148798505915458	MEF2C/VEGFA/STAT1/MAGED1/CD24/LAMA5/NOTCH1/LGR5/TACSTD2/NOTCH2/AHI1/GATA3/PBX1/COL4A1/LGR4/YAP1/DLG1/GLI3/IRX2/GPC3	20
GO:1902414	protein localization to cell junction	20/2053	94/18722	0.00264613343019656	0.0148798505915458	PECAM1/FLNA/ACTB/DSP/JAK1/NSG1/DAG1/ZDHHC12/LSR/HRAS/MARVELD3/DLG5/JAM3/TJP1/RAP1A/FERMT2/VCL/DLG1/CLSTN1/MPP7	20
GO:0009306	protein secretion	57/2053	359/18722	0.00265488264947016	0.0148968427513459	HLA-DRB1/PLEK/TGFB1/TLR2/EGFR/UCP2/JAK2/ALOX5/TNF/TLR4/IL1B/MYH10/WLS/IL1RN/GLUL/MPC2/SERP1/PPIA/DPP4/RSAD2/TREM2/ADAM8/PDIA4/CD33/RHBDF2/ERP29/IDH2/GJA1/FAM3B/HMGN3/UQCC2/TRPM2/KLF7/ISL1/SYT7/FRMD4A/SOX4/HADH/ACSL4/SLC16A1/LRP5/RAB3D/KCNN4/CYB5R4/CAMK2G/PARK7/PHPT1/EZR/BAD/TCIRG1/MIDN/DNAJC1/CD2AP/ENSA/P3H1/TM7SF3/CCDC186	57
GO:0035272	exocrine system development	12/2053	45/18722	0.00265660362399002	0.0148968427513459	TGFB1/TNF/WLS/TGM2/DAG1/BMP7/LAMA5/NRP1/TFCP2L1/FOXC1/IGSF3/PDGFA	12
GO:0035305	negative regulation of dephosphorylation	12/2053	45/18722	0.00265660362399002	0.0148968427513459	NCKAP1L/TNF/LGALS3/GNAI2/CHP1/YWHAE/MASTL/FKBP1A/PPP1R15A/ENSA/PPP1R35/URI1	12
GO:0050851	antigen receptor-mediated signaling pathway	41/2053	240/18722	0.00267370572429616	0.0149702004590475	HLA-A/LAPTM5/HLA-DPB1/MNDA/PTPRC/HLA-DRB1/HLA-DQB1/NCKAP1L/LYN/LAT2/MEF2C/CD300A/LILRB4/THEMIS2/GBP1/LCP2/PRAM1/RPS3/BTK/SYK/PTPN6/CSK/LGALS3/NFAM1/SLC39A10/CMTM3/PRKCB/PAWR/HRAS/GATA3/KCNN4/STOML2/NFKBIZ/BCAR1/INPP5D/PHPT1/EZR/VAV3/BTN3A1/UBE2N/PLEKHA1	41
GO:0006278	RNA-dependent DNA biosynthetic process	17/2053	75/18722	0.00267467581534983	0.0149702004590475	HSP90AA1/HSP90AB1/PKIB/HNRNPA1/NHP2/RFC1/TCP1/CCT6A/CCT2/XRCC5/RAD50/PNKP/RPA1/CCT4/AURKB/CCT8/MAP3K4	17
GO:0031330	negative regulation of cellular catabolic process	44/2053	262/18722	0.00268154795463617	0.0149946763539767	TSPO/TIMP1/SLC11A1/ZFP36/SORL1/CST3/IL10RA/LRRK2/HMOX1/NAMPT/RPS7/MET/FUS/PABPC1/QSOX1/HSP90AB1/RPL5/TIMP2/TIMP3/TREM2/RPL23/PBK/MCL1/APOC1/SLIRP/STAT3/HNRNPD/SMARCC1/SDCBP/MYD88/ATRAID/EFNA1/USP14/SVIP/HNRNPA0/PARK7/SNRNP70/PTPN3/LRPPRC/E2F1/EIF4G1/YBX1/MAPK14/ALAD	44
GO:0032147	activation of protein kinase activity	26/2053	134/18722	0.00268827259613662	0.0150043121644835	SLC11A1/NCKAP1L/CD86/CD300A/HMGB1/JAK2/VEGFA/TLR6/CLSPN/PPIA/IL6R/PTK2B/EMP2/RPLP1/PHB2/CCDC88A/TPX2/TXN/RGCC/PHB/PARK7/ECT2/DLG1/INSR/IL18/PRKAG2	26
GO:0061041	regulation of wound healing	26/2053	134/18722	0.00268827259613662	0.0150043121644835	CXCR4/CLEC7A/CD9/HMGB1/ALOX5/PRDX2/TNF/TNFAIP3/CD36/CLDN4/ITGB1/HPSE/SH2B3/GJA1/HBEGF/KANK1/FERMT1/HRAS/TNFRSF12A/PLPP3/FERMT2/C1QTNF1/UBASH3B/PTK2/PDGFA/SERPING1	26
GO:0007095	mitotic G2 DNA damage checkpoint signaling	10/2053	34/18722	0.0027101162805873	0.0150841351424154	CLSPN/CDK1/BRCA1/DTL/CHEK1/TOPBP1/BLM/FOXO4/CDKN1A/BRCC3	10
GO:0009112	nucleobase metabolic process	10/2053	34/18722	0.0027101162805873	0.0150841351424154	TYMP/TYMS/RRM1/DPYD/CDA/PAICS/UMPS/GMPS/SHMT1/PPAT	10
GO:0010922	positive regulation of phosphatase activity	10/2053	34/18722	0.0027101162805873	0.0150841351424154	PTPRC/PLEK/MEF2C/CD300A/JAK2/HSP90AB1/CD33/SLC39A10/CALM2/PPP1R15A	10
GO:0051656	establishment of organelle localization	61/2053	390/18722	0.00274793387822605	0.0152804478863357	LGALS9/CD84/LYN/LAT2/MYO1F/CD300A/RAC2/MYO1G/FGR/LRRK2/SYNE2/ITGA4/HMOX1/STXBP2/ADGRE2/BTK/RAN/SYK/ITGB1/CENPF/NUSAP1/NPM1/MAD2L1/TMED9/GJA1/UBB/CDT1/CHP1/KPNB1/ACTR2/CDCA5/NUF2/PARD3/SNX4/MYO1C/KIF22/ARMCX3/ACTR3/NDC80/FNBP1L/EML4/ARHGAP21/EZR/DLG1/TCIRG1/NUDC/AURKB/CHMP4C/PICALM/MYO5A/GPSM2/LRPPRC/CFL1/CDCA8/S100A13/TFG/CCDC186/ACTN4/MYO7A/DYNLT1/KIFC1	61
GO:0034605	cellular response to heat	16/2053	69/18722	0.00275963510139989	0.0153171235970391	LYN/TFEC/HSPD1/HMOX1/CXCL10/RBBP7/HSP90AA1/HSP90AB1/HSPA6/HDAC2/TPR/YWHAE/HSPA1A/HSBP1L1/CDKN1A/VCP	16
GO:0045669	positive regulation of osteoblast differentiation	16/2053	69/18722	0.00275963510139989	0.0153171235970391	MEF2C/FBN2/CEBPB/BMP7/IL6R/CLIC1/FBXO5/IL6ST/PDLIM7/LRP5/ATRAID/YAP1/FERMT2/GLI3/SMAD5/SUCO	16
GO:0014009	glial cell proliferation	13/2053	51/18722	0.00277759138977009	0.0154025400541779	TSPO/LYN/EGFR/TNF/IL1B/NOTCH1/TREM2/PTK2B/IDH2/ASCL2/SOX4/PTN/E2F1	13
GO:0051100	negative regulation of binding	30/2053	162/18722	0.00280871688686454	0.0155546931274438	TMSB4X/SORL1/B2M/IFIT2/ACTB/JAK2/LRRK2/IFIT1/IFI16/ITGA4/HMOX1/ARRB2/LRPAP1/CTSZ/NFKBIA/CAMK1/CARD16/ID1/C4orf3/HDAC2/RALB/BAG2/PTPRF/MSX2/SP100/JUN/PARK7/CDKN1A/AURKB/E2F1	30
GO:0031214	biomineral tissue development	31/2053	169/18722	0.00281021455835818	0.0155546931274438	SRGN/CCL3/ISG15/TGFB1/SLC8A1/MEF2C/FBN2/FGR/SPP1/SNX10/ALOX5/CCR1/CEBPB/GPNMB/BMP7/NOTCH1/ATP2B1/PTK2B/NOTUM/P2RX7/BMP2K/ASGR2/TFAP2A/FBXO5/LGR4/ATRAID/SLC20A1/SBDS/TCIRG1/PTN/GPC3	31
GO:2000756	regulation of peptidyl-lysine acetylation	15/2053	63/18722	0.00281340587774163	0.0155580048538707	SPI1/IL1B/BRCA1/HINT2/SET/CHEK1/ISL1/SOX4/HDAC2/BRD7/GATA3/EID1/PARK7/ZNF451/RPS6KA5	15
GO:0033619	membrane protein proteolysis	14/2053	57/18722	0.00282419879550059	0.0155977909703381	TIMP1/TNFRSF1B/TGFB1/TNF/IL1B/CTSH/DAG1/TIMP2/TIMP3/ADAM8/AFG3L2/RBMX/PTPN3/PACSIN3	14
GO:0035592	establishment of protein localization to extracellular region	57/2053	360/18722	0.00282579979745959	0.0155977909703381	HLA-DRB1/PLEK/TGFB1/TLR2/EGFR/UCP2/JAK2/ALOX5/TNF/TLR4/IL1B/MYH10/WLS/IL1RN/GLUL/MPC2/SERP1/PPIA/DPP4/RSAD2/TREM2/ADAM8/PDIA4/CD33/RHBDF2/ERP29/IDH2/GJA1/FAM3B/HMGN3/UQCC2/TRPM2/KLF7/ISL1/SYT7/FRMD4A/SOX4/HADH/ACSL4/SLC16A1/LRP5/RAB3D/KCNN4/CYB5R4/CAMK2G/PARK7/PHPT1/EZR/BAD/TCIRG1/MIDN/DNAJC1/CD2AP/ENSA/P3H1/TM7SF3/CCDC186	57
GO:0042177	negative regulation of protein catabolic process	24/2053	121/18722	0.00284760800604268	0.0157037206215589	TIMP1/FLNA/CST3/EGFR/IRAK3/RPS7/HSP90AB1/RPL5/TIMP2/TIMP3/RPL23/MAD2L1/PBK/SMARCC1/SDCBP/ATRAID/EFNA1/USP14/SVIP/PHB/PARK7/SNRNP70/PTPN3/ALAD	24
GO:0000028	ribosomal small subunit assembly	7/2053	19/18722	0.00288321729957973	0.0157984509566012	RPS5/RPSA/RPS27/PRKDC/RPS14/RPS19/XRCC5	7
GO:0030050	vesicle transport along actin filament	7/2053	19/18722	0.00288321729957973	0.0157984509566012	MYO1F/MYO1G/MYO1C/FNBP1L/MYO5A/ACTN4/MYO7A	7
GO:0032695	negative regulation of interleukin-12 production	7/2053	19/18722	0.00288321729957973	0.0157984509566012	LILRB1/IRAK3/ARRB2/LILRA5/TLR8/C1QBP/ACP5	7
GO:0034501	protein localization to kinetochore	7/2053	19/18722	0.00288321729957973	0.0157984509566012	CDK1/CDT1/BUB3/NDC80/TTK/AURKB/KNTC1	7
GO:0044546	NLRP3 inflammasome complex assembly	7/2053	19/18722	0.00288321729957973	0.0157984509566012	GBP5/TLR4/CD36/TLR6/TREM2/AIM2/MYD88	7
GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate	7/2053	19/18722	0.00288321729957973	0.0157984509566012	APOBEC3A/TOP2A/CXCL8/APOBEC3G/APOBEC3C/TOP2B/TRIM28	7
GO:1903083	protein localization to condensed chromosome	7/2053	19/18722	0.00288321729957973	0.0157984509566012	CDK1/CDT1/BUB3/NDC80/TTK/AURKB/KNTC1	7
GO:0001916	positive regulation of T cell mediated cytotoxicity	9/2053	29/18722	0.00292335496738569	0.0159746173081185	HLA-B/HLA-A/HLA-DRA/PTPRC/HLA-DRB1/HLA-F/B2M/HLA-E/CD1D	9
GO:0070198	protein localization to chromosome, telomeric region	9/2053	29/18722	0.00292335496738569	0.0159746173081185	TPP1/TCP1/CCT6A/BRCA2/CCT2/XRCC5/GNL3/CCT4/CCT8	9
GO:0090025	regulation of monocyte chemotaxis	9/2053	29/18722	0.00292335496738569	0.0159746173081185	AIF1/LYN/DUSP1/HMGB1/CCR1/CCR2/CXCL10/PLA2G7/CX3CR1	9
GO:0035303	regulation of dephosphorylation	25/2053	128/18722	0.0029278223661712	0.0159844715168582	PTPRC/PLEK/TGFB1/NCKAP1L/LILRB2/MEF2C/CD300A/JAK2/HSP90B1/TNF/HSP90AB1/PPIA/LGALS3/CD33/SLC39A10/GNAI2/CHP1/CALM2/YWHAE/MASTL/FKBP1A/PPP1R15A/ENSA/PPP1R35/URI1	25
GO:0060348	bone development	36/2053	205/18722	0.00293894102386838	0.0160305874029184	TYROBP/PTPRC/MEF2C/LILRB1/SNX10/FBN1/GNAS/PTGER4/TGM2/PTPN6/RARA/ENG/PPIB/HSD17B1/FLI1/NOTUM/SH2B3/SERPINH1/GJA1/TFAP2A/SULF2/BBX/RHOA/NOTCH2/LRP5/ACP5/MSX2/WASF2/SBDS/GLI3/FOXC1/VKORC1/P3H1/SMAD5/MAPK14/ASXL1	36
GO:0001101	response to acid chemical	26/2053	135/18722	0.00299000433556785	0.0162943015562281	CYBB/CYBA/LYN/CD9/VEGFA/PCNA/KLF2/TNF/GSTP1/CEBPB/DNMT1/ICAM1/KRT8/AKR1B1/CDO1/RHOA/LAMTOR4/HNRNPD/GCLM/ASS1/COL4A1/BAD/IPO5/SLC38A9/PTN/ALAD	26
GO:0036473	cell death in response to oxidative stress	20/2053	95/18722	0.00301360381456765	0.0163476955045526	PAGE4/GPX1/SOD2/JAK2/LRRK2/TLR4/PARP1/P4HB/MET/TLR6/SOD1/PPIA/TREM2/MCL1/PAWR/TRPM2/TXN/PARK7/TRAP1/SIGMAR1	20
GO:0002726	positive regulation of T cell cytokine production	8/2053	24/18722	0.00301614982058995	0.0163476955045526	HLA-A/B2M/IL1B/SASH3/NLRP3/RSAD2/GATA3/IL18	8
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	8/2053	24/18722	0.00301614982058995	0.0163476955045526	TYMP/DUT/UPP1/TYMS/DPYD/UNG/DTYMK/DCTPP1	8
GO:0035458	cellular response to interferon-beta	8/2053	24/18722	0.00301614982058995	0.0163476955045526	MNDA/IFITM2/IFI16/STAT1/IRF1/AIM2/OAS1/NDUFA13	8
GO:0072530	purine-containing compound transmembrane transport	8/2053	24/18722	0.00301614982058995	0.0163476955045526	AQP9/SLC25A5/LRRC8C/SLC29A1/SLC25A4/SLC19A1/SLC25A17/SLC25A6	8
GO:0090343	positive regulation of cell aging	8/2053	24/18722	0.00301614982058995	0.0163476955045526	B2M/ABI3/PAWR/EEF1E1/HMGA1/CDKN2A/YPEL3/LMNA	8
GO:0002714	positive regulation of B cell mediated immunity	11/2053	40/18722	0.00304063397398205	0.0164062984207665	PTPRC/TGFB1/HLA-E/TNF/C3/BTK/STAT6/TREM2/MSH2/RIF1/TFRC	11
GO:0002891	positive regulation of immunoglobulin mediated immune response	11/2053	40/18722	0.00304063397398205	0.0164062984207665	PTPRC/TGFB1/HLA-E/TNF/C3/BTK/STAT6/TREM2/MSH2/RIF1/TFRC	11
GO:0010863	positive regulation of phospholipase C activity	11/2053	40/18722	0.00304063397398205	0.0164062984207665	C5AR1/CD86/EGFR/PTAFR/S1PR4/PLCB2/GNA15/PHB2/FLT1/HRAS/PHB	11
GO:0045740	positive regulation of DNA replication	11/2053	40/18722	0.00304063397398205	0.0164062984207665	EGFR/PCNA/CDK1/ATAD5/CDT1/HRAS/CACYBP/DBF4/STOML2/JUN/E2F7	11
GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	11/2053	40/18722	0.00304063397398205	0.0164062984207665	ITGB2/KLF4/ALOX5/TNF/ITGA4/PTAFR/CCR2/ICAM1/RHOA/MDK/NFAT5	11
GO:0030278	regulation of ossification	23/2053	115/18722	0.00308617888815122	0.0166370829549931	SRGN/CCL3/ISG15/TGFB1/SLC8A1/MEF2C/FBN2/ALOX5/CCR1/PTGER4/BMP7/NOTCH1/ATP2B1/PTK2B/NOTUM/P2RX7/BMP2K/TFAP2A/PBX1/ATRAID/MDK/PTN/MAPK14	23
GO:0032543	mitochondrial translation	17/2053	76/18722	0.00310046679873431	0.0166991030452477	C1QBP/IARS2/UQCC2/MRPS34/MRPS15/MRPL16/MRPL51/TSFM/MRPL57/MRPL2/MRPS6/MRPL43/CHCHD1/MALSU1/LRPPRC/MRPL47/MRPS21	17
GO:0043542	endothelial cell migration	46/2053	279/18722	0.00314761734800574	0.0169378512000309	TMSB4X/TGFB1/MEF2C/HMGB1/GPX1/KLF4/VEGFA/TNF/SERPINF1/HMOX1/GRN/MET/NRP2/VASH1/GLUL/ITGB1/DPP4/SEMA4A/NOTCH1/NR2F2/CALR/TNFSF12/PTK2B/NR4A1/EMP2/FSTL1/STAT5A/RRAS/ID1/AMOT/NRP1/RHOA/CIB1/RGCC/GATA3/EPHB4/PLPP3/EFNA1/ANXA3/SP100/BCAR1/RHOB/PLK2/PTN/PTK2/PPARG	46
GO:0044818	mitotic G2/M transition checkpoint	12/2053	46/18722	0.00324179084557539	0.017401885292893	CLSPN/CDK1/CDC6/BRCA1/NAE1/DTL/CHEK1/TOPBP1/BLM/FOXO4/CDKN1A/BRCC3	12
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	12/2053	46/18722	0.00324179084557539	0.017401885292893	AIF1/EGFR/CDC6/CCND1/ADAMTS1/CCND3/RDX/RGCC/TFDP1/APEX1/KMT2E/EIF4G1	12
GO:0051962	positive regulation of nervous system development	45/2053	272/18722	0.00324255129290907	0.017401885292893	TSPO/CXCR4/TNFRSF1B/TGFB1/LYN/TLR2/FN1/SPINT1/SKIL/EGFR/VEGFA/PLXNC1/LRP2/TNF/IL1B/SERPINF1/TGM2/DAG1/MME/SEMA4A/NOTCH1/TRPV2/ASPM/CX3CR1/NAP1L1/TPBG/NRP1/ACTR2/RHEB/HDAC2/GOLGA4/IL6ST/DLG5/TWF2/XRCC5/OBSL1/GLI3/ID2/NUMB/MDK/PTN/PRPF19/E2F1/CLSTN1/XRCC2	45
GO:0001885	endothelial cell development	15/2053	64/18722	0.00330938892852258	0.0177288692599424	MSN/PECAM1/GPX1/VEGFA/TNF/IL1B/MYADM/MET/ICAM1/RDX/MYD88/TJP1/RAP1A/VCL/EZR	15
GO:0070542	response to fatty acid	15/2053	64/18722	0.00330938892852258	0.0177288692599424	TLR2/UCP2/CD36/PTAFR/TBXAS1/PDK4/GLDC/CDK4/ASS1/ID3/XRCC5/BAD/NME1/E2F1/ALAD	15
GO:1903050	regulation of proteolysis involved in cellular protein catabolic process	38/2053	221/18722	0.00333714598545164	0.0178514357249674	LAPTM5/GPX1/LRRK2/RPS7/PLK3/HSP90AB1/RPL5/TREM2/RPL23/PTK2B/PSME2/PSMC3/UBB/PBK/TRIB1/PSMC1/NUDT15/SMARCC1/PSMD14/SDCBP/EFNA1/BAG2/USP14/SVIP/PITHD1/PSMC2/MAGEF1/TMTC3/PARK7/COMMD1/RAD23B/HSPA1A/CDK2/VCP/PLK2/GABARAP/PTK2/ALAD	38
GO:0072009	nephron epithelium development	22/2053	109/18722	0.0033382184805689	0.0178514357249674	PECAM1/MEF2C/VEGFA/STAT1/MAGED1/CD24/LAMA5/NOTCH1/TACSTD2/NOTCH2/AHI1/GATA3/PBX1/LGR4/YAP1/DLG1/GLI3/FOXC1/BASP1/IRX2/ASXL1/GPC3	22
GO:0001954	positive regulation of cell-matrix adhesion	14/2053	58/18722	0.00335425522175008	0.0178893611826671	VEGFA/CD36/DAG1/PTK2B/EMP2/RRAS/S100A10/LIMS1/FERMT1/PLEKHA2/NRP1/CIB1/CDK6/FERMT2	14
GO:0042743	hydrogen peroxide metabolic process	14/2053	58/18722	0.00335425522175008	0.0178893611826671	CYBA/RAC2/GPX1/EGFR/SOD2/PRDX2/PRDX4/PRDX5/SOD1/STAT3/PRDX3/PRDX6/PRDX1/PARK7	14
GO:1902808	positive regulation of cell cycle G1/S phase transition	14/2053	58/18722	0.00335425522175008	0.0178893611826671	AIF1/EGFR/CDC6/CCND1/PHB2/EZH2/ADAMTS1/CCND3/RDX/RGCC/TFDP1/APEX1/KMT2E/EIF4G1	14
GO:0110148	biomineralization	31/2053	171/18722	0.00338111620814039	0.0180166050167339	SRGN/CCL3/ISG15/TGFB1/SLC8A1/MEF2C/FBN2/FGR/SPP1/SNX10/ALOX5/CCR1/CEBPB/GPNMB/BMP7/NOTCH1/ATP2B1/PTK2B/NOTUM/P2RX7/BMP2K/ASGR2/TFAP2A/FBXO5/LGR4/ATRAID/SLC20A1/SBDS/TCIRG1/PTN/GPC3	31
GO:0001893	maternal placenta development	10/2053	35/18722	0.00342710481227278	0.0182292809163445	CTSB/JUNB/SPP1/BSG/NR2F2/CTSV/GJA1/PRDX3/VDR/PTN	10
GO:0039694	viral RNA genome replication	10/2053	35/18722	0.00342710481227278	0.0182292809163445	APOBEC3A/TOP2A/CXCL8/APOBEC3G/APOBEC3C/PHB/TOP2B/ATG16L2/TRIM28/EEA1	10
GO:0048738	cardiac muscle tissue development	40/2053	236/18722	0.00344792170877392	0.0183237646170447	TGFB1/SLC8A1/MEF2C/VEGFA/LRP2/DSP/ARRB2/RUNX1/MEF2A/RARA/CDK1/BMP7/ITGB1/ENG/NOTCH1/CALR/HAMP/DSG2/GJA1/GJA5/ISL1/NOTCH2/CACYBP/YAP1/PARP2/MSX2/OBSL1/RGS2/SLC9A1/NDUFV2/FHL2/FKBP1A/ID2/FOXC1/TGFBR3/KDM6B/LMNA/SMAD5/TBX3/MAPK14	40
GO:0007006	mitochondrial membrane organization	23/2053	116/18722	0.0034589650438797	0.0183661860736975	HSP90AA1/SLC25A5/HK2/BNIP3L/TIMM13/PMAIP1/STAT3/SLC25A4/PDCD5/IMMT/HEBP2/CHCHD10/AFG3L2/SLC9A1/HSPA1A/BAD/NMT1/BNIP3/MTX1/MTX2/HSPA9/NDUFA13/DYNLT1	23
GO:0045444	fat cell differentiation	39/2053	229/18722	0.00353061879164518	0.0187300731652264	ZFP36/PSMB8/TGFB1/MAFB/ZFP36L2/PLAC8/GPX1/KLF4/RETN/ALOX5/TNF/ADIRF/NR4A2/METRNL/CEBPB/BMP7/ZFP36L1/NR4A1/CCND1/JDP2/ADRB1/GATA3/ATF5/LRP5/YAP1/KLF5/ANKRD26/FERMT2/ARID5B/RGS2/CDS1/BNIP3/ID2/STK4/E2F1/NOC3L/MAPK14/ASXL1/PPARG	39
GO:0002679	respiratory burst involved in defense response	6/2053	15/18722	0.00359424791545084	0.0189005148928177	NCF1/HCK/PRDX2/GRN/TREM2/RPS19	6
GO:0002730	regulation of dendritic cell cytokine production	6/2053	15/18722	0.00359424791545084	0.0189005148928177	BST2/CLEC7A/SCIMP/TLR4/DDX1/DDX58	6
GO:0009263	deoxyribonucleotide biosynthetic process	6/2053	15/18722	0.00359424791545084	0.0189005148928177	DUT/TYMS/RRM1/DTYMK/RRM2/ADK	6
GO:0016446	somatic hypermutation of immunoglobulin genes	6/2053	15/18722	0.00359424791545084	0.0189005148928177	SAMHD1/UNG/MSH2/MSH6/POLQ/EXO1	6
GO:0030852	regulation of granulocyte differentiation	6/2053	15/18722	0.00359424791545084	0.0189005148928177	EVI2B/RUNX1/RARA/TRIB1/HCLS1/INPP5D	6
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	6/2053	15/18722	0.00359424791545084	0.0189005148928177	IL1B/LILRA2/SYK/ISL1/DDX58/IL18	6
GO:0045064	T-helper 2 cell differentiation	6/2053	15/18722	0.00359424791545084	0.0189005148928177	CD86/NLRP3/RARA/BCL6/GATA3/IL18	6
GO:0055012	ventricular cardiac muscle cell differentiation	6/2053	15/18722	0.00359424791545084	0.0189005148928177	MEF2C/MEF2A/RARA/CDK1/FHL2/LMNA	6
GO:1904874	positive regulation of telomerase RNA localization to Cajal body	6/2053	15/18722	0.00359424791545084	0.0189005148928177	NHP2/TCP1/CCT6A/CCT2/CCT4/CCT8	6
GO:1905168	positive regulation of double-strand break repair via homologous recombination	6/2053	15/18722	0.00359424791545084	0.0189005148928177	WAS/PARP1/FUS/RAD51AP1/ACTR2/TIMELESS	6
GO:0120032	regulation of plasma membrane bounded cell projection assembly	33/2053	186/18722	0.00362979880278982	0.0190707467747276	WAS/RAC2/ABI3/P2RX7/ICAM1/CCDC88A/KANK1/TACSTD2/HRAS/RDX/TRPM2/NRP1/ACTR2/SH3YL1/TWF2/ANLN/YAP1/KLF5/ACTR3/FNBP1L/WASF2/PFN1/RHOG/EPS8/RHOQ/CORO1C/VDAC3/EPS8L2/ATMIN/DOCK11/CCP110/ODF2L/COBL	33
GO:0030879	mammary gland development	26/2053	137/18722	0.00368007258711579	0.0193179663365658	CSF1R/OAS2/GPX1/JAK2/VEGFA/CEBPB/STAT6/CCND1/STAT5A/HK2/SLC29A1/PHB2/CDO1/UMPS/VDR/GATA3/LRP5/BRCA2/NCOR2/GLI3/ID2/MTX1/NME1/TBX3/CAPN1/PPAT	26
GO:1901136	carbohydrate derivative catabolic process	31/2053	172/18722	0.00370170802633692	0.0194145525856831	APOBEC3A/TYMP/CD44/TGFB1/SAMHD1/CST3/DUT/UPP1/CTSL/HINT1/AOAH/DPYD/UNG/HPSE/CDA/PDE4A/APOBEC3G/NUDT8/ALDH1A1/APOBEC3C/FUCA1/FBXO6/NUDT15/PNP/IDS/NUDT4/GPC1/DCTPP1/AMPD3/HEXB/DNPH1	31
GO:0046661	male sex differentiation	30/2053	165/18722	0.00372343298890893	0.0195114392431909	TNFSF10/FLNA/NASP/LRP2/HMGB2/RRM1/LHFPL2/ADGRG1/PRDX4/RARA/DHCR24/ICAM1/CCND1/CTSV/ASPM/RHOBTB3/MSH2/UBB/SF1/GATA3/LGR4/MGST1/ARID5B/ERCC1/ING2/SMAD5/TBX3/PLEKHA1/FANCA/TFAP2C	30
GO:0061515	myeloid cell development	16/2053	71/18722	0.00374280573933426	0.0195696085234177	TYROBP/EVI2B/NCKAP1L/LILRB1/TLR2/FBN1/KLF2/APP/PTPN6/BCL6/FLI1/SH2B3/FAM210B/NOTCH2/RPS6/WASF2	16
GO:0048259	regulation of receptor-mediated endocytosis	22/2053	110/18722	0.00375042889747235	0.0195696085234177	B2M/VEGFA/ARRB2/C3/LRPAP1/SYK/BMP2K/PPT1/AAK1/APOC1/RIN3/AHI1/ITGAV/SDCBP/CD63/DGKD/CD2AP/NUMB/INSR/PICALM/AP2M1/LDLRAP1	22
GO:0050691	regulation of defense response to virus by host	11/2053	41/18722	0.00375084163365507	0.0195696085234177	PYCARD/LILRB1/TNFAIP3/STAT1/HSP90AA1/PARP9/AIM2/APOBEC3G/DTX3L/EIF2AK4/DDX58	11
GO:0050856	regulation of T cell receptor signaling pathway	11/2053	41/18722	0.00375084163365507	0.0195696085234177	LAPTM5/CD300A/LILRB4/GBP1/RPS3/PTPN6/LGALS3/PAWR/KCNN4/PHPT1/EZR	11
GO:0071470	cellular response to osmotic stress	11/2053	41/18722	0.00375084163365507	0.0195696085234177	TSPO/SLC2A1/RCSD1/ZFP36L1/LRRC8C/AKR1B1/XRCC5/XRCC6/ARHGEF2/BAD/EFHD1	11
GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	9/2053	30/18722	0.00377587496428003	0.0196660154389585	LAPTM5/CD300A/LILRB4/GBP1/PTPN6/LGALS3/PAWR/PHPT1/EZR	9
GO:0090314	positive regulation of protein targeting to membrane	9/2053	30/18722	0.00377587496428003	0.0196660154389585	ITGB2/ITGAM/TCAF1/HRAS/CHP1/CIB1/MYO1C/ANK3/FIS1	9
GO:0006403	RNA localization	35/2053	201/18722	0.00383250971652828	0.0199436758882651	ZFP36/MX2/SLBP/RAN/HHEX/ZFP36L1/NPM1/HNRNPA3/HNRNPA1/NUP214/IGF2BP3/NHP2/UPF3A/TCP1/NOP58/NXT1/MAGOHB/CCT6A/MYO1C/MAGOH/KHSRP/TPR/CCT2/NCBP3/RANBP17/HNRNPA2B1/SRSF7/MVP/CCT4/PABPN1/CCT8/LRPPRC/NUP54/FBL/YBX1	35
GO:0010712	regulation of collagen metabolic process	12/2053	47/18722	0.00392684288154112	0.0203815374474453	VIM/TGFB1/CST3/ARRB2/RUNX1/CIITA/ITGB1/ENG/HDAC2/RGCC/RAP1A/SUCO	12
GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	12/2053	47/18722	0.00392684288154112	0.0203815374474453	VEGFA/KLF2/HMOX1/CEBPB/NOTCH1/HSPA5/CHEK1/EPAS1/BACH1/JUN/HSPA1A/ATF3	12
GO:0045911	positive regulation of DNA recombination	12/2053	47/18722	0.00392684288154112	0.0203815374474453	PTPRC/TGFB1/WAS/PARP1/FUS/STAT6/RAD51AP1/MSH2/ACTR2/TIMELESS/RIF1/TFRC	12
GO:0043620	regulation of DNA-templated transcription in response to stress	13/2053	53/18722	0.00398793884710931	0.0206807546090371	VEGFA/KLF2/HMOX1/CEBPB/NOTCH1/HSPA5/CHEK1/EPAS1/RPS6KA1/BACH1/JUN/HSPA1A/ATF3	13
GO:0046039	GTP metabolic process	8/2053	25/18722	0.00401491115933674	0.0207070377623439	GIMAP7/LRRK2/RAN/RHOA/NME4/IMPDH2/RHOQ/NME1	8
GO:0048143	astrocyte activation	8/2053	25/18722	0.00401491115933674	0.0207070377623439	C5AR1/EGFR/TNF/APP/GRN/TREM2/C1QA/IFNGR1	8
GO:0071459	protein localization to chromosome, centromeric region	8/2053	25/18722	0.00401491115933674	0.0207070377623439	CDK1/CDT1/BUB3/NDC80/TTK/AURKB/BUB1B/KNTC1	8
GO:0090330	regulation of platelet aggregation	8/2053	25/18722	0.00401491115933674	0.0207070377623439	LYN/CD9/JAK2/SYK/SH2B3/IL6ST/C1QTNF1/UBASH3B	8
GO:1905048	regulation of metallopeptidase activity	8/2053	25/18722	0.00401491115933674	0.0207070377623439	TIMP1/SORL1/MBP/CLDN4/TIMP2/TIMP3/STAT3/PICALM	8
GO:0034104	negative regulation of tissue remodeling	7/2053	20/18722	0.00402061649885511	0.0207070377623439	CST3/TNFAIP3/CSK/HAMP/P2RX7/INPP5D/UBASH3B	7
GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate	7/2053	20/18722	0.00402061649885511	0.0207070377623439	APOBEC3A/TOP2A/CXCL8/APOBEC3G/APOBEC3C/TOP2B/TRIM28	7
GO:1901679	nucleotide transmembrane transport	7/2053	20/18722	0.00402061649885511	0.0207070377623439	SLC25A5/LRRC8C/SLC25A36/SLC25A4/SLC19A1/SLC25A17/SLC25A6	7
GO:0010498	proteasomal protein catabolic process	73/2053	490/18722	0.00405417698278856	0.0208619741824454	PSMB9/PSMB8/GPX1/LRRK2/HSP90B1/ARRB2/PLK3/HSP90AB1/PSMD7/CALR/CCDC47/TREM2/PSME2/HSPA5/ANAPC11/IFI27/PSMC3/UBE2C/UBB/PBK/KLHL42/PMAIP1/PSMA3/TRIB1/DDB1/PSMD1/PSMB2/SIAH2/UBE2S/PSMB5/PSMC1/PSMB6/FBXO6/NUDT15/SMARCC1/PSMB1/PSMD14/SDCBP/UBXN4/PSMD2/BAG2/USP14/SVIP/ANKRD9/SDF2L1/PITHD1/PSMC2/SIAH1/TMTC3/UBXN2A/PSMB10/PARK7/COMMD1/RAD23B/HSPA1A/PSMD12/SGTB/TBL1X/CDK2/CD2AP/PSMB7/PSMA1/ASCC3/SKP2/VCP/PLK2/PRPF19/GABARAP/HUWE1/DNAJB14/DNAJB9/UBE4B/ALAD	73
GO:1903076	regulation of protein localization to plasma membrane	21/2053	104/18722	0.0040582417091556	0.020864995933962	TGFB1/ACTB/ABI3/EGFR/TNF/GBP1/CSK/ITGB1/LGALS3/TREM2/CIB1/SPTBN1/GOPC/RHOG/RHOQ/EZR/DLG1/NUMB/PICALM/AP2M1/LDLRAP1	21
GO:0009743	response to carbohydrate	42/2053	253/18722	0.0040830842917615	0.0209166787030207	TXNIP/HLA-DRB1/LGALS1/CYBA/CLEC7A/LYN/SLC8A1/UCP2/SOD2/COLEC12/SERPINF1/GSTP1/NAMPT/KRT18/GLUL/MPC2/ZFP36L1/TREM2/PTK2B/ICAM1/CTSV/SLC29A1/PRKCB/GJA1/HMGN3/CDT1/KLF7/LDHA/RHOA/SOX4/GCLM/LRP5/RAP1A/FIS1/PHPT1/ERCC1/BAD/IGF1R/TRA2B/ENSA/NME1/CCDC186	42
GO:0098754	detoxification	28/2053	152/18722	0.00410665845366225	0.0209166787030207	GPX1/SOD2/ALOX5AP/MGST3/PRDX2/CD36/GSTP1/PRDX4/GLRX/PRDX5/SOD1/MT1X/BMP7/S100A9/DHFR/GPX8/ADH5/ALDH1A1/MT2A/TXN/PRDX3/PRDX6/PRDX1/MGST1/SOD3/PARK7/GCH1/PTGES	28
GO:0002357	defense response to tumor cell	5/2053	11/18722	0.00412755793072941	0.0209166787030207	LAPTM5/SPI1/ABI3/KLF4/PRDX2	5
GO:0032493	response to bacterial lipoprotein	5/2053	11/18722	0.00412755793072941	0.0209166787030207	CD14/TLR2/TLR1/CD36/TLR6	5
GO:0034975	protein folding in endoplasmic reticulum	5/2053	11/18722	0.00412755793072941	0.0209166787030207	HSP90B1/P4HB/PDIA3/CALR/HSPA5	5
GO:0045628	regulation of T-helper 2 cell differentiation	5/2053	11/18722	0.00412755793072941	0.0209166787030207	CD86/NLRP3/RARA/BCL6/IL18	5
GO:0045657	positive regulation of monocyte differentiation	5/2053	11/18722	0.00412755793072941	0.0209166787030207	HLA-DRB1/CD74/CD4/ZFP36L1/JUN	5
GO:0046643	regulation of gamma-delta T cell activation	5/2053	11/18722	0.00412755793072941	0.0209166787030207	PTPRC/NCKAP1L/LILRB1/SYK/SOX4	5
GO:0048102	autophagic cell death	5/2053	11/18722	0.00412755793072941	0.0209166787030207	LAPTM5/TREM2/CTSV/PHB2/BNIP3	5
GO:0070203	regulation of establishment of protein localization to telomere	5/2053	11/18722	0.00412755793072941	0.0209166787030207	TCP1/CCT6A/CCT2/CCT4/CCT8	5
GO:0098883	synapse pruning	5/2053	11/18722	0.00412755793072941	0.0209166787030207	ITGAM/C3/TREM2/C1QA/CX3CR1	5
GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	5/2053	11/18722	0.00412755793072941	0.0209166787030207	GBP5/TLR4/CD36/TLR6/MYD88	5
GO:1902337	regulation of apoptotic process involved in morphogenesis	5/2053	11/18722	0.00412755793072941	0.0209166787030207	TNFRSF1B/BMP7/NOTCH1/VDR/FOXC1	5
GO:1904869	regulation of protein localization to Cajal body	5/2053	11/18722	0.00412755793072941	0.0209166787030207	TCP1/CCT6A/CCT2/CCT4/CCT8	5
GO:1904871	positive regulation of protein localization to Cajal body	5/2053	11/18722	0.00412755793072941	0.0209166787030207	TCP1/CCT6A/CCT2/CCT4/CCT8	5
GO:1905668	positive regulation of protein localization to endosome	5/2053	11/18722	0.00412755793072941	0.0209166787030207	MSN/SORL1/RDX/DTX3L/EZR	5
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	5/2053	11/18722	0.00412755793072941	0.0209166787030207	CD74/HMGB1/MBP/TNF/TLR4	5
GO:0048511	rhythmic process	48/2053	298/18722	0.00414758525796372	0.0210004316858923	EGFR/RETN/PCNA/TYMS/SERPINF1/NAMPT/ARRB2/NR2F6/MAGED1/PRKDC/TOP2A/CLDN4/CDK1/KCNQ1/HNRNPR/HSPA5/ID1/EZH2/DTL/ADAMTS1/DDB1/TRPM2/SLC6A4/ADRB1/CBX3/SIAH2/HDAC2/HNRNPD/ATF5/CDK4/BHLHE40/ASS1/LGR4/ID3/NCOR2/ID4/GNA11/IMPDH2/JUN/TIMELESS/ID2/MDK/BHLHE41/PTN/GFPT1/HUWE1/PLEKHA1/PPARG	48
GO:0030073	insulin secretion	34/2053	195/18722	0.00423491391644162	0.021406473040143	HLA-DRB1/UCP2/JAK2/ALOX5/TNF/IL1B/IL1RN/GLUL/MPC2/SERP1/DPP4/GJA1/FAM3B/HMGN3/UQCC2/TRPM2/KLF7/ISL1/SYT7/SOX4/HADH/ACSL4/SLC16A1/LRP5/CYB5R4/CAMK2G/PARK7/PHPT1/BAD/TCIRG1/MIDN/ENSA/TM7SF3/CCDC186	34
GO:0070302	regulation of stress-activated protein kinase signaling cascade	34/2053	195/18722	0.00423491391644162	0.021406473040143	NCF1/SPI1/CLEC7A/PYCARD/LYN/PAGE4/DUSP1/SCIMP/HMGB1/EGFR/VEGFA/TNF/TLR4/IL1B/GSTP1/APP/PPIA/GADD45B/TREM2/PTK2B/PBK/HRAS/SPHK1/MARVELD3/SIRPA/SDCBP/MYD88/PRDX1/RASSF2/EZR/DLG1/IGF1R/FOXM1/MAP3K4	34
GO:0010923	negative regulation of phosphatase activity	10/2053	36/18722	0.00428676146220229	0.0216321015754531	NCKAP1L/TNF/LGALS3/GNAI2/CHP1/MASTL/FKBP1A/PPP1R15A/PPP1R35/URI1	10
GO:0060251	regulation of glial cell proliferation	10/2053	36/18722	0.00428676146220229	0.0216321015754531	TSPO/LYN/EGFR/TNF/IL1B/NOTCH1/IDH2/ASCL2/PTN/E2F1	10
GO:0030336	negative regulation of cell migration	54/2053	344/18722	0.00429668649811979	0.0216639655367385	AIF1/TIMP1/CD74/BST2/ARHGDIB/TGFB1/MEF2C/CD300A/DUSP1/HMGB1/KLF4/TCAF1/CDH1/TNF/SERPINF1/GSTP1/HMOX1/ADGRG1/PTGER4/CNN2/VASH1/DAG1/IL27RA/DPP4/ENG/NOTCH1/NR2F2/CALR/MCTP1/ARHGAP4/LDLRAD4/RRAS/IDH2/GJA1/CX3CR1/KANK1/TACSTD2/TRIB1/RHOA/MARVELD3/STAT3/RIN3/RGCC/DLG5/SEMA6D/ABHD2/SP100/APEX1/VCL/CORO1C/RHOB/PTN/PTPRU/PPARG	54
GO:0060491	regulation of cell projection assembly	33/2053	188/18722	0.00430465894243658	0.0216859392566074	WAS/RAC2/ABI3/P2RX7/ICAM1/CCDC88A/KANK1/TACSTD2/HRAS/RDX/TRPM2/NRP1/ACTR2/SH3YL1/TWF2/ANLN/YAP1/KLF5/ACTR3/FNBP1L/WASF2/PFN1/RHOG/EPS8/RHOQ/CORO1C/VDAC3/EPS8L2/ATMIN/DOCK11/CCP110/ODF2L/COBL	33
GO:0043903	regulation of biological process involved in symbiotic interaction	16/2053	72/18722	0.00433279184779401	0.0218093549385605	HLA-DRB1/LGALS1/CD74/FCN1/IFITM2/LGALS9/TRIM22/IFITM3/CD4/P4HB/CIITA/CXCL8/DDB1/ITGAV/TRIM38/TRIM28	16
GO:0045667	regulation of osteoblast differentiation	25/2053	132/18722	0.00446324250745492	0.0224471542705193	MEF2C/FBN2/TNF/CEBPB/BMP7/NOTCH1/CRIM1/IL6R/CLIC1/FBXO5/IL6ST/PDLIM7/LRP5/ID3/ATRAID/YAP1/CDK6/FERMT2/RASSF2/TCIRG1/GLI3/SMAD5/PTK2/SUCO/PPARG	25
GO:0007043	cell-cell junction assembly	27/2053	146/18722	0.00451552080720018	0.0226910593326642	PECAM1/MTDH/CD9/ACTB/TNF/IL1B/GPBAR1/CLDN4/CLDN7/GJA1/LSR/CNTNAP2/GJA5/RHOA/MARVELD3/PARD3/ARL2/DLG5/MYO1C/JAM3/TJP1/VCL/ECT2/PARD6B/DLG1/CTNND1/MPP7	27
GO:0006364	rRNA processing	38/2053	225/18722	0.00455105776104509	0.0228504992186364	RPS21/ISG20/PA2G4/RPS17/RPS7/RPS27/PRKDC/RPS16/RPS14/RPL5/RPL7A/POP7/EXOSC8/RPS19/NOP56/RPL35/NHP2/RPL10A/NOP58/RPL14/RBFA/RPS6/RPS8/SNU13/MRPL1/RPL7/IMP3/WDR18/SBDS/KRR1/BRIX1/WBP11/RPS25/DDX18/FBL/PWP1/MRTO4/BMS1	38
GO:0009124	nucleoside monophosphate biosynthetic process	11/2053	42/18722	0.00458747391178703	0.0229564999755815	DUT/UPP1/TYMS/PAICS/TK1/UMPS/GMPS/ADK/IMPDH2/AMPD3/PPAT	11
GO:0032689	negative regulation of interferon-gamma production	11/2053	42/18722	0.00458747391178703	0.0229564999755815	LAPTM5/HLA-DRB1/LGALS9/HAVCR2/LILRB1/LILRB4/HMGB1/TLR4/RARA/C1QBP/GATA3	11
GO:1900274	regulation of phospholipase C activity	11/2053	42/18722	0.00458747391178703	0.0229564999755815	C5AR1/CD86/EGFR/PTAFR/S1PR4/PLCB2/GNA15/PHB2/FLT1/HRAS/PHB	11
GO:2000404	regulation of T cell migration	11/2053	42/18722	0.00458747391178703	0.0229564999755815	AIF1/PYCARD/TNFRSF14/APP/ITGA4/CCR2/CXCL10/IL27RA/ADAM8/SPN/RHOA	11
GO:0031032	actomyosin structure organization	34/2053	196/18722	0.00459741910070195	0.0229679555405593	PHACTR1/WAS/GPR65/STMN1/MYH10/CSRP2/PTGER4/PDLIM1/CNN2/MET/MEF2A/ITGB1/PTK2B/CCDC88A/TACSTD2/KRT8/CNN3/S100A10/NRP1/RHOA/FRMD6/ITGB5/RGCC/ZYX/ANLN/TJP1/FERMT2/WASF2/PFN1/OBSL1/SLC9A1/ECT2/EPB41/RTKN	34
GO:0043393	regulation of protein binding	34/2053	196/18722	0.00459741910070195	0.0229679555405593	SORL1/B2M/IFIT2/ACTB/LRRK2/IFIT1/PHLDA2/APP/ITGA4/ARRB2/LRPAP1/CTSZ/RAN/HSP90AB1/CAMK1/CARD16/ID1/MFNG/NRP1/RALB/BAG2/PTPRF/DTX3L/PARK7/CDKN1A/FKBP1A/AURKB/STK4/TGFBR3/PLK2/UBASH3B/AKTIP/EPB41/LDLRAP1	34
GO:0002673	regulation of acute inflammatory response	12/2053	48/18722	0.0047234698510695	0.0235025183758874	HLA-E/ALOX5AP/TNF/IL1B/GSTP1/C3/BTK/NLRP3/ADAM8/IL6ST/PARK7/PTGES	12
GO:0033628	regulation of cell adhesion mediated by integrin	12/2053	48/18722	0.0047234698510695	0.0235025183758874	NCKAP1L/LYN/FERMT3/SYK/PTPN6/DPP4/FERMT1/CIB1/JAM3/EFNA1/PTK2/RAC3	12
GO:0048146	positive regulation of fibroblast proliferation	12/2053	48/18722	0.0047234698510695	0.0235025183758874	CD74/S100A6/FN1/PRKDC/CDC6/SPHK1/CCNA2/CDK4/CDK6/CDKN1A/PDGFA/E2F1	12
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	17/2053	79/18722	0.0047265810300175	0.0235025183758874	FLNA/MYADM/P4HB/PRKDC/PREX1/CALR/S100A10/LIMS1/C1QBP/NRP1/ACTR2/CIB1/FERMT2/OBSL1/MDK/TRIOBP/RAC3	17
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	17/2053	79/18722	0.0047265810300175	0.0235025183758874	HCST/NCF1/PIK3AP1/FN1/FGR/JAK2/TNF/PTPN6/TREM2/FLT1/MYDGF/HCLS1/IGF1R/INSR/PTK2/PDGFA/IL18	17
GO:0001706	endoderm formation	13/2053	54/18722	0.00473575745274132	0.0235025183758874	ITGB2/DUSP1/FN1/ITGA5/ITGA4/DUSP2/LAMB1/COL4A2/RTF1/ITGB5/ITGAV/DUSP5/MMP15	13
GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	13/2053	54/18722	0.00473575745274132	0.0235025183758874	SPI1/TGFB1/LILRB4/FOS/KLF4/TNF/STAT3/GATA3/KLF5/GNL3/TEAD1/JUN/PPARG	13
GO:2000179	positive regulation of neural precursor cell proliferation	13/2053	54/18722	0.00473575745274132	0.0235025183758874	FLNA/LYN/VEGFA/LRP2/ADGRG1/CTSZ/NOTCH1/ASPM/CX3CR1/NAP1L1/GNAI2/GLI3/MDK	13
GO:0006301	postreplication repair	9/2053	31/18722	0.00481127802258622	0.0238182080326051	PCNA/BRCA1/MSH2/DTL/USP10/WDR33/VCP/UBE2N/POLE2	9
GO:0071480	cellular response to gamma radiation	9/2053	31/18722	0.00481127802258622	0.0238182080326051	CYBA/RAD51/HSPA5/HRAS/XRCC5/YAP1/XRCC6/CDKN1A/TMEM109	9
GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	9/2053	31/18722	0.00481127802258622	0.0238182080326051	GPX1/TNFAIP3/HMGB2/HMOX1/ICAM1/BRCA1/PARK7/ARHGEF2/PEA15	9
GO:0009166	nucleotide catabolic process	16/2053	73/18722	0.00499663985478199	0.0247154485809497	TYMP/SAMHD1/DUT/UPP1/HINT1/DPYD/UNG/PDE4A/NUDT8/NUDT15/PNP/NUDT4/DCTPP1/AMPD3/VCP/DNPH1	16
GO:0042886	amide transport	48/2053	301/18722	0.00503959644958189	0.0249073959616897	S100A8/HLA-DRB1/CD74/PSAP/EGFR/UCP2/JAK2/LRP2/ALOX5/TAP2/TNF/AQP9/IL1B/IL1RN/TAP1/GLUL/MPC2/SERP1/DPP4/GJA1/SLC15A3/FAM3B/HMGN3/TAPBP/UQCC2/TRPM2/KLF7/ISL1/SYT7/SOX4/HADH/ACSL4/SLC16A1/FOLR1/LRP5/SLC19A1/MGST1/CYB5R4/CAMK2G/PARK7/SLC13A3/PHPT1/BAD/TCIRG1/MIDN/ENSA/TM7SF3/CCDC186	48
GO:0030038	contractile actin filament bundle assembly	21/2053	106/18722	0.0051139173128211	0.0251917109005965	PHACTR1/WAS/GPR65/STMN1/PTGER4/PDLIM1/MET/PTK2B/CCDC88A/TACSTD2/S100A10/NRP1/RHOA/ITGB5/RGCC/ZYX/TJP1/FERMT2/WASF2/PFN1/SLC9A1	21
GO:0035821	modulation of process of other organism	21/2053	106/18722	0.0051139173128211	0.0251917109005965	CCL3/CCL4/CLEC7A/CD4/MPEG1/SYK/DAG1/NUCKS1/S100A9/PPIB/P2RX7/IFI27/PHB2/PSMC3/CX3CR1/HSPA8/PHB/EIF2AK4/JUN/INSR/CFL1	21
GO:0043149	stress fiber assembly	21/2053	106/18722	0.0051139173128211	0.0251917109005965	PHACTR1/WAS/GPR65/STMN1/PTGER4/PDLIM1/MET/PTK2B/CCDC88A/TACSTD2/S100A10/NRP1/RHOA/ITGB5/RGCC/ZYX/TJP1/FERMT2/WASF2/PFN1/SLC9A1	21
GO:1905477	positive regulation of protein localization to membrane	21/2053	106/18722	0.0051139173128211	0.0251917109005965	ITGB2/EGFR/ITGAM/TCAF1/TNF/ITGB1/LGALS3/TREM2/HRAS/CHP1/CIB1/PDCD5/MYO1C/ANK3/SPTBN1/RHOG/FIS1/EZR/DLG1/NMT1/PTN	21
GO:0002371	dendritic cell cytokine production	6/2053	16/18722	0.0052227354473868	0.025302925149822	BST2/CLEC7A/SCIMP/TLR4/DDX1/DDX58	6
GO:0002566	somatic diversification of immune receptors via somatic mutation	6/2053	16/18722	0.0052227354473868	0.025302925149822	SAMHD1/UNG/MSH2/MSH6/POLQ/EXO1	6
GO:0002693	positive regulation of cellular extravasation	6/2053	16/18722	0.0052227354473868	0.025302925149822	PTAFR/CCR2/ADAM8/ICAM1/JAM3/MDK	6
GO:0006206	pyrimidine nucleobase metabolic process	6/2053	16/18722	0.0052227354473868	0.025302925149822	TYMP/TYMS/RRM1/DPYD/CDA/UMPS	6
GO:0006266	DNA ligation	6/2053	16/18722	0.0052227354473868	0.025302925149822	HMGB1/TOP2A/RAD51/LIG1/PNKP/XRCC6	6
GO:0010649	regulation of cell communication by electrical coupling	6/2053	16/18722	0.0052227354473868	0.025302925149822	SLC8A1/GJA1/CAMK2D/GJA5/CALM2/ANK3	6
GO:0017014	protein nitrosylation	6/2053	16/18722	0.0052227354473868	0.025302925149822	S100A8/S100A9/ADH5/TXN/DMD/GAPDH	6
GO:0018119	peptidyl-cysteine S-nitrosylation	6/2053	16/18722	0.0052227354473868	0.025302925149822	S100A8/S100A9/ADH5/TXN/DMD/GAPDH	6
GO:0034138	toll-like receptor 3 signaling pathway	6/2053	16/18722	0.0052227354473868	0.025302925149822	HAVCR2/SCIMP/TNFAIP3/COLEC12/OAS1/UNC93B1	6
GO:0045342	MHC class II biosynthetic process	6/2053	16/18722	0.0052227354473868	0.025302925149822	SLC11A1/SPI1/JAK2/TLR4/CIITA/HDAC2	6
GO:0045779	negative regulation of bone resorption	6/2053	16/18722	0.0052227354473868	0.025302925149822	TNFAIP3/CSK/HAMP/P2RX7/INPP5D/UBASH3B	6
GO:0046135	pyrimidine nucleoside catabolic process	6/2053	16/18722	0.0052227354473868	0.025302925149822	APOBEC3A/UPP1/DPYD/CDA/APOBEC3G/APOBEC3C	6
GO:0051014	actin filament severing	6/2053	16/18722	0.0052227354473868	0.025302925149822	GMFG/CAPG/FMNL1/DSTN/SCIN/CFL1	6
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	6/2053	16/18722	0.0052227354473868	0.025302925149822	TLR2/JAK2/LRRK2/TLR4/STAT1/NAMPT	6
GO:0070200	establishment of protein localization to telomere	6/2053	16/18722	0.0052227354473868	0.025302925149822	TCP1/CCT6A/BRCA2/CCT2/CCT4/CCT8	6
GO:0090231	regulation of spindle checkpoint	6/2053	16/18722	0.0052227354473868	0.025302925149822	DUSP1/MAD2L1/CDT1/TPR/NDC80/LCMT1	6
GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	6/2053	16/18722	0.0052227354473868	0.025302925149822	DUSP1/MAD2L1/CDT1/TPR/NDC80/LCMT1	6
GO:1903504	regulation of mitotic spindle checkpoint	6/2053	16/18722	0.0052227354473868	0.025302925149822	DUSP1/MAD2L1/CDT1/TPR/NDC80/LCMT1	6
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	6/2053	16/18722	0.0052227354473868	0.025302925149822	GLRX/CHP1/ANK3/SLC9A1/DMD/ACTN4	6
GO:0015833	peptide transport	43/2053	264/18722	0.00524249414585266	0.025302925149822	S100A8/HLA-DRB1/CD74/EGFR/UCP2/JAK2/ALOX5/TAP2/TNF/IL1B/IL1RN/TAP1/GLUL/MPC2/SERP1/DPP4/GJA1/SLC15A3/FAM3B/HMGN3/TAPBP/UQCC2/TRPM2/KLF7/ISL1/SYT7/SOX4/HADH/ACSL4/SLC16A1/LRP5/MGST1/CYB5R4/CAMK2G/PARK7/SLC13A3/PHPT1/BAD/TCIRG1/MIDN/ENSA/TM7SF3/CCDC186	43
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	55/2053	355/18722	0.00524497945097772	0.025302925149822	VIM/ZEB2/SPI1/TGFB1/SORL1/PEG10/FOS/SKIL/FBN2/JAK2/FBN1/LRP2/PARP1/ARRB2/HSP90AB1/BMP7/NREP/ENG/NOTCH1/CRIM1/HSPA5/FSTL1/LDLRAD4/ID1/CDKN1C/HPGD/FERMT1/LTBP1/RBPMS/USP15/ITGB5/NOTCH2/STAT3/ZYX/FOLR1/UBE2D1/SDCBP/FUT8/SPTBN1/FERMT2/JUN/TTK/HSPA1A/FKBP1A/ING2/ZNF451/TGFBR3/EID2/SMAD5/CTDSPL2/PTK2/ITGB8/MAPK14/PPARG/GPC3	55
GO:0033598	mammary gland epithelial cell proliferation	8/2053	26/18722	0.00525035696858807	0.025302925149822	GPX1/CEBPB/STAT6/CCND1/PHB2/GATA3/BRCA2/ID2	8
GO:0034114	regulation of heterotypic cell-cell adhesion	8/2053	26/18722	0.00525035696858807	0.025302925149822	CD44/KLF4/MBP/TNF/IL1B/MYADM/IL1RN/BMP7	8
GO:0043094	cellular metabolic compound salvage	8/2053	26/18722	0.00525035696858807	0.025302925149822	UPP1/CDA/ADI1/MTAP/PNP/ADK/AMPD3/ENOPH1	8
GO:0046697	decidualization	8/2053	26/18722	0.00525035696858807	0.025302925149822	CTSB/JUNB/SPP1/BSG/CTSV/GJA1/VDR/PTN	8
GO:0097066	response to thyroid hormone	8/2053	26/18722	0.00525035696858807	0.025302925149822	CTSS/CTSB/LMO2/CTSL/CTSH/AKR1B1/RDX/GCLM	8
GO:1905523	positive regulation of macrophage migration	8/2053	26/18722	0.00525035696858807	0.025302925149822	CCL3/CSF1R/C5AR1/C3AR1/TREM2/CX3CR1/MDK/PTK2	8
GO:0045137	development of primary sexual characteristics	38/2053	227/18722	0.00528686888805295	0.0254584376631763	TNFSF10/FLNA/NASP/RETN/VEGFA/LRP2/HMGB2/RRM1/CEBPB/LHFPL2/ADGRG1/ARRB2/PRDX4/SOD1/RARA/NR2F2/HSPA5/ICAM1/CCND1/CTSV/ASPM/RHOBTB3/MSH2/UBB/ADAMTS1/SF1/GATA3/BRCA2/MGST1/IDH1/ARID5B/ERCC1/ING2/FOXC1/BASP1/PLEKHA1/FANCA/TFAP2C	38
GO:0003161	cardiac conduction system development	10/2053	37/18722	0.00530765165627111	0.025517556039765	NOTCH1/DSG2/GJA1/GJA5/ISL1/NOTCH2/MSX2/ID2/SMAD5/TBX3	10
GO:0072529	pyrimidine-containing compound catabolic process	10/2053	37/18722	0.00530765165627111	0.025517556039765	APOBEC3A/TYMP/DUT/UPP1/DPYD/UNG/CDA/APOBEC3G/APOBEC3C/DCTPP1	10
GO:0033273	response to vitamin	19/2053	93/18722	0.00533129877886944	0.0255902341385733	TSPO/EGFR/SOD2/SPP1/TYMS/GSTP1/KYNU/CXCL10/RARA/BMP7/SRSF2/ATP2B1/HAMP/CCND1/VDR/FOLR1/TRIM24/PTN/ALAD	19
GO:0060993	kidney morphogenesis	19/2053	93/18722	0.00533129877886944	0.0255902341385733	LRRK2/VEGFA/STAT1/MAGED1/BMP7/LAMA5/TACSTD2/FRAS1/SOX4/AHI1/GATA3/PBX1/LGR4/DLG1/GLI3/BASP1/IRX2/ASXL1/GPC3	19
GO:0051494	negative regulation of cytoskeleton organization	29/2053	162/18722	0.0053841112826823	0.025823075696318	TMSB4X/GMFG/CORO1A/CAPG/WAS/TMSB10/STMN1/MYADM/MET/NPM1/BRCA1/KANK1/TACSTD2/RDX/CIB1/TPX2/KANK4/CKAP2/TWF2/SCIN/MID1IP1/SPTBN1/TJP1/WASF2/PFN1/EPS8/ARHGEF2/LIMA1/TRIOBP	29
GO:0032204	regulation of telomere maintenance	17/2053	80/18722	0.0054028630256864	0.0258510192616574	PARP1/PKIB/HNRNPA1/HNRNPD/TCP1/CCT6A/CCT2/XRCC5/RAD50/PNKP/GNL3/HNRNPA2B1/ERCC1/CCT4/AURKB/CCT8/MAP3K4	17
GO:0048145	regulation of fibroblast proliferation	17/2053	80/18722	0.0054028630256864	0.0258510192616574	CD74/IFI30/FTH1/S100A6/CD300A/FN1/GSTP1/PRKDC/CDC6/PAWR/SPHK1/CCNA2/CDK4/CDK6/CDKN1A/PDGFA/E2F1	17
GO:0120193	tight junction organization	17/2053	80/18722	0.0054028630256864	0.0258510192616574	PECAM1/MTDH/TNF/GPBAR1/CLDN4/CLDN7/SVEP1/GJA1/LSR/MARVELD3/PARD3/ARL2/MYO1C/TJP1/ECT2/DLG1/MPP7	17
GO:0007252	I-kappaB phosphorylation	7/2053	21/18722	0.0054677131472755	0.0259748843100974	TLR2/TNF/TLR4/PRDX4/TLR7/CX3CR1/SIRPA	7
GO:0045056	transcytosis	7/2053	21/18722	0.0054677131472755	0.0259748843100974	FCGRT/LRP2/PTAFR/LRPAP1/MAL2/IGF1R/PICALM	7
GO:0046641	positive regulation of alpha-beta T cell proliferation	7/2053	21/18722	0.0054677131472755	0.0259748843100974	HLA-A/PTPRC/LGALS9/HLA-E/CCR2/SYK/IL18	7
GO:0051767	nitric-oxide synthase biosynthetic process	7/2053	21/18722	0.0054677131472755	0.0259748843100974	TLR2/JAK2/LRRK2/TLR4/GSTP1/STAT1/NAMPT	7
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	7/2053	21/18722	0.0054677131472755	0.0259748843100974	TLR2/JAK2/LRRK2/TLR4/GSTP1/STAT1/NAMPT	7
GO:0060445	branching involved in salivary gland morphogenesis	7/2053	21/18722	0.0054677131472755	0.0259748843100974	TNF/TGM2/DAG1/BMP7/LAMA5/NRP1/PDGFA	7
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	7/2053	21/18722	0.0054677131472755	0.0259748843100974	LAPTM5/CD74/LILRB1/TLR4/CD36/DDX1/DDX58	7
GO:0090026	positive regulation of monocyte chemotaxis	7/2053	21/18722	0.0054677131472755	0.0259748843100974	AIF1/HMGB1/CCR1/CCR2/CXCL10/PLA2G7/CX3CR1	7
GO:2000774	positive regulation of cellular senescence	7/2053	21/18722	0.0054677131472755	0.0259748843100974	B2M/ABI3/PAWR/EEF1E1/HMGA1/CDKN2A/YPEL3	7
GO:0061640	cytoskeleton-dependent cytokinesis	20/2053	100/18722	0.00555063415494343	0.0263479469380226	STMN1/MYH10/NUSAP1/RASA1/RHOA/ACTR2/KIF23/CKAP2/ANK3/ANLN/KIF20B/SPTBN1/ACTR3/ECT2/TTC19/RHOB/AURKB/CHMP4C/KIF4A/RTKN	20
GO:0006509	membrane protein ectodomain proteolysis	11/2053	43/18722	0.00556551742327912	0.0263768598259674	TIMP1/TNFRSF1B/TNF/IL1B/DAG1/TIMP2/TIMP3/ADAM8/RBMX/PTPN3/PACSIN3	11
GO:0031952	regulation of protein autophosphorylation	11/2053	43/18722	0.00556551742327912	0.0263768598259674	PTPRC/VEGFA/GPNMB/ENG/NLRP12/CHP1/CALM2/RAD50/RASSF2/MVP/PDGFA	11
GO:0061614	pri-miRNA transcription by RNA polymerase II	13/2053	55/18722	0.00559216987713479	0.0264822567188703	SPI1/TGFB1/LILRB4/FOS/KLF4/TNF/STAT3/GATA3/KLF5/GNL3/TEAD1/JUN/PPARG	13
GO:0006953	acute-phase response	12/2053	49/18722	0.00564397824174989	0.0266644641342515	SERPINA1/FN1/TNF/IL1B/CEBPB/IL6R/HAMP/CD163/STAT3/ASS1/PLSCR1/PTGES	12
GO:0034332	adherens junction organization	12/2053	49/18722	0.00564397824174989	0.0266644641342515	ACTB/VEGFA/CDH1/DSP/CSK/RDX/DLG5/JAM3/TJP1/FERMT2/VCL/NUMB	12
GO:0045778	positive regulation of ossification	12/2053	49/18722	0.00564397824174989	0.0266644641342515	ISG15/TGFB1/SLC8A1/MEF2C/FBN2/ALOX5/BMP7/ATP2B1/P2RX7/TFAP2A/ATRAID/PTN	12
GO:1903578	regulation of ATP metabolic process	18/2053	87/18722	0.00573939493457437	0.0270797584699767	TSPO/TMSB4X/FBP1/PARP1/APP/TREM2/P2RX7/DDIT4/SLC2A6/UQCC2/RHOA/STAT3/ARL2/COX7A2/FIS1/INSR/VCP/PRKAG2	18
GO:0120192	tight junction assembly	16/2053	74/18722	0.00574090879563505	0.0270797584699767	PECAM1/MTDH/TNF/GPBAR1/CLDN4/CLDN7/GJA1/LSR/MARVELD3/PARD3/ARL2/MYO1C/TJP1/ECT2/DLG1/MPP7	16
GO:0008406	gonad development	37/2053	221/18722	0.00585129180793474	0.0275787516477678	TNFSF10/FLNA/NASP/RETN/VEGFA/LRP2/HMGB2/RRM1/CEBPB/ADGRG1/ARRB2/PRDX4/SOD1/RARA/NR2F2/HSPA5/ICAM1/CCND1/CTSV/ASPM/RHOBTB3/MSH2/UBB/ADAMTS1/SF1/GATA3/BRCA2/MGST1/IDH1/ARID5B/ERCC1/ING2/FOXC1/BASP1/PLEKHA1/FANCA/TFAP2C	37
GO:0032872	regulation of stress-activated MAPK cascade	33/2053	192/18722	0.00597599053517532	0.0281443824262574	NCF1/SPI1/CLEC7A/PYCARD/PAGE4/DUSP1/SCIMP/HMGB1/EGFR/VEGFA/TNF/TLR4/IL1B/GSTP1/APP/PPIA/GADD45B/TREM2/PTK2B/PBK/HRAS/SPHK1/MARVELD3/SIRPA/SDCBP/MYD88/PRDX1/RASSF2/EZR/DLG1/IGF1R/FOXM1/MAP3K4	33
GO:0019693	ribose phosphate metabolic process	60/2053	396/18722	0.00599613056466789	0.0282011290095382	TMSB4X/TGFB1/UPP1/GIMAP7/LRRK2/HINT1/FBP1/PARP1/APP/KYNU/DPYD/SLC26A2/RAN/MPC2/ACSS1/TECR/TREM2/HK3/PDK4/PAICS/P2RX7/PDE4A/HK2/DDIT4/PPT1/SLC2A6/SULT1A1/NUDT8/ALDOA/SLC25A1/LDHA/RHOA/UMPS/STAT3/PNP/ARL2/ACSL4/GMPS/DHTKD1/RPIA/TPST2/PMVK/PDHA1/STOML2/NME4/ADK/NUDT4/IMPDH2/NUDT5/RHOQ/DLG1/BAD/MPP1/AMPD3/INSR/VCP/NME1/PPAT/GAPDH/PRKAG2	60
GO:0046546	development of primary male sexual characteristics	26/2053	142/18722	0.00601148037083561	0.0282011290095382	TNFSF10/FLNA/NASP/LRP2/HMGB2/RRM1/LHFPL2/ADGRG1/PRDX4/RARA/ICAM1/CCND1/CTSV/ASPM/RHOBTB3/MSH2/UBB/SF1/GATA3/MGST1/ARID5B/ERCC1/ING2/PLEKHA1/FANCA/TFAP2C	26
GO:0072006	nephron development	26/2053	142/18722	0.00601148037083561	0.0282011290095382	PECAM1/MEF2C/VEGFA/STAT1/MAGED1/CD24/BMP7/LAMA5/NOTCH1/IL6R/ENPEP/TACSTD2/SULF2/NOTCH2/AHI1/GATA3/PBX1/LGR4/YAP1/DLG1/GLI3/FOXC1/BASP1/IRX2/ASXL1/GPC3	26
GO:0032091	negative regulation of protein binding	19/2053	94/18722	0.0060115406671999	0.0282011290095382	SORL1/B2M/IFIT2/ACTB/LRRK2/IFIT1/ITGA4/ARRB2/LRPAP1/CTSZ/CAMK1/CARD16/ID1/RALB/BAG2/PTPRF/PARK7/CDKN1A/AURKB	19
GO:0051702	biological process involved in interaction with symbiont	19/2053	94/18722	0.0060115406671999	0.0282011290095382	CCL3/CCL4/FN1/GPX1/TREM1/HSPD1/NUCKS1/PPIB/IFI27/PSMC3/CX3CR1/HSPA8/DDB1/MYD88/PHB/EIF2AK4/JUN/CFL1/GAPDH	19
GO:0008156	negative regulation of DNA replication	9/2053	32/18722	0.00605420823094114	0.0283127430909173	GMNN/S100A11/BCL6/CDC6/FBXO5/BLM/BRCA2/TIPIN/TIMELESS	9
GO:0050850	positive regulation of calcium-mediated signaling	9/2053	32/18722	0.00605420823094114	0.0283127430909173	CCL3/CCL4/CLEC7A/CD4/TNF/SYK/TREM2/CIB1/SLC9A1	9
GO:0051642	centrosome localization	9/2053	32/18722	0.00605420823094114	0.0283127430909173	SYNE2/MAD2L1/ASPM/PARD3/EZR/DLG1/DYNC1LI2/AKAP9/GPSM2	9
GO:1905476	negative regulation of protein localization to membrane	9/2053	32/18722	0.00605420823094114	0.0283127430909173	TGFB1/ABI3/GBP1/CSK/GOPC/RHOQ/NUMB/PICALM/AP2M1	9
GO:1901607	alpha-amino acid biosynthetic process	15/2053	68/18722	0.00606012395660072	0.0283183362457978	SDS/GLUL/DHFR/SDSL/ADI1/MTAP/OAT/ASS1/PARK7/PYCR2/PLOD2/SHMT1/ASNSD1/MTR/ENOPH1	15
GO:0048144	fibroblast proliferation	17/2053	81/18722	0.00615588971408347	0.0287211028650862	CD74/IFI30/FTH1/S100A6/CD300A/FN1/GSTP1/PRKDC/CDC6/PAWR/SPHK1/CCNA2/CDK4/CDK6/CDKN1A/PDGFA/E2F1	17
GO:2000106	regulation of leukocyte apoptotic process	17/2053	81/18722	0.00615588971408347	0.0287211028650862	CD74/TSC22D3/LGALS9/LYN/MEF2C/LILRB1/IRF7/BTK/LGALS3/BCL6/ADAM8/SLC39A10/TCP1/EFNA1/CDKN2A/HCLS1/AURKB	17
GO:0006576	cellular biogenic amine metabolic process	20/2053	101/18722	0.00622524814073221	0.0289996031400569	ITGB2/ITGAM/OAZ1/NR4A2/KYNU/SAT1/IL4I1/ALDH7A1/COMT/PNKD/SULT1A1/AKR1B1/EPAS1/SMS/GATA3/SRM/PARK7/GCH1/SAT2/SLC44A1	20
GO:0050830	defense response to Gram-positive bacterium	20/2053	101/18722	0.00622524814073221	0.0289996031400569	HLA-A/LYZ/PYCARD/C5AR1/GBP4/GBP2/HLA-E/HAVCR2/TLR2/FGR/TNFRSF14/TNF/HMGB2/CD36/MPEG1/RNASE6/IL27RA/MYD88/ACP5/DEFB1	20
GO:0019932	second-messenger-mediated signaling	49/2053	312/18722	0.00623786857967665	0.0290358506424049	PTPRC/CXCR4/CCL3/FPR1/PLEK/CCL4/CLEC7A/LAT2/SLC8A1/EGFR/LRRK2/VEGFA/CD4/CCR1/TNF/HOMER3/CD36/GBP1/CCR2/BTK/SYK/CCRL2/MCTP1/TREM2/PTK2B/P2RX7/PDE4A/DDAH2/CX3CR1/CAMK2D/CXCL8/CHP1/CAP1/TRPM2/SPHK1/CALM2/CIB1/P2RY11/GNAI1/FIS1/NUDT4/DGKD/RGS2/SLC9A1/FHL2/DMD/DEFB1/ADGRG6/NFAT5	49
GO:0015931	nucleobase-containing compound transport	37/2053	222/18722	0.00629932914519908	0.0292992053265074	ZFP36/MX2/SLBP/RAN/SLC25A5/HHEX/ZFP36L1/NPM1/LRRC8C/HNRNPA3/HNRNPA1/NUP214/SLC29A1/GJA1/IGF2BP3/SLC35B4/SLC25A36/SLC25A4/UPF3A/NXT1/MAGOHB/SLC19A1/MYO1C/MAGOH/KHSRP/TPR/NCBP3/RANBP17/HNRNPA2B1/SRSF7/MVP/PABPN1/SLC25A17/LRPPRC/NUP54/SLC25A6/YBX1	37
GO:0010573	vascular endothelial growth factor production	14/2053	62/18722	0.00634355868748775	0.0294820698101677	TGFB1/C5AR1/C3AR1/TNF/IL1B/ADGRG1/CCR2/C3/HPSE/IL6R/BRCA1/SULF2/ISL1/IL6ST	14
GO:0002424	T cell mediated immune response to tumor cell	5/2053	12/18722	0.00644210369146757	0.0295283591663907	HLA-A/HLA-DRB1/HMGB1/HSPD1/IL4I1	5
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	5/2053	12/18722	0.00644210369146757	0.0295283591663907	HLA-E/TNF/C3/BTK/PARK7	5
GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process	5/2053	12/18722	0.00644210369146757	0.0295283591663907	TYMP/DUT/UPP1/TYMS/DPYD	5
GO:0031953	negative regulation of protein autophosphorylation	5/2053	12/18722	0.00644210369146757	0.0295283591663907	PTPRC/ENG/NLRP12/CHP1/MVP	5
GO:0032736	positive regulation of interleukin-13 production	5/2053	12/18722	0.00644210369146757	0.0295283591663907	LGALS9/HLA-E/RARA/GATA3/IL18	5
GO:0033004	negative regulation of mast cell activation	5/2053	12/18722	0.00644210369146757	0.0295283591663907	LGALS9/CD84/CD300A/HMOX1/CD300LF	5
GO:0043380	regulation of memory T cell differentiation	5/2053	12/18722	0.00644210369146757	0.0295283591663907	HLA-DRA/HLA-DRB1/FGL2/CD46/BCL6	5
GO:0051255	spindle midzone assembly	5/2053	12/18722	0.00644210369146757	0.0295283591663907	PRC1/KIF23/AURKB/KIF4A/CCDC69	5
GO:0060907	positive regulation of macrophage cytokine production	5/2053	12/18722	0.00644210369146757	0.0295283591663907	LAPTM5/CD74/LILRB1/TLR4/CD36	5
GO:0070202	regulation of establishment of protein localization to chromosome	5/2053	12/18722	0.00644210369146757	0.0295283591663907	TCP1/CCT6A/CCT2/CCT4/CCT8	5
GO:0070493	thrombin-activated receptor signaling pathway	5/2053	12/18722	0.00644210369146757	0.0295283591663907	PLEK/STMN1/MET/IQGAP2/HPGD	5
GO:0071472	cellular response to salt stress	5/2053	12/18722	0.00644210369146757	0.0295283591663907	ZFP36L1/AKR1B1/XRCC5/XRCC6/EFHD1	5
GO:1903405	protein localization to nuclear body	5/2053	12/18722	0.00644210369146757	0.0295283591663907	TCP1/CCT6A/CCT2/CCT4/CCT8	5
GO:1903599	positive regulation of autophagy of mitochondrion	5/2053	12/18722	0.00644210369146757	0.0295283591663907	SLC25A5/SLC25A4/VDAC1/PARK7/BNIP3	5
GO:1904748	regulation of apoptotic process involved in development	5/2053	12/18722	0.00644210369146757	0.0295283591663907	TNFRSF1B/BMP7/NOTCH1/VDR/FOXC1	5
GO:1904867	protein localization to Cajal body	5/2053	12/18722	0.00644210369146757	0.0295283591663907	TCP1/CCT6A/CCT2/CCT4/CCT8	5
GO:1905245	regulation of aspartic-type peptidase activity	5/2053	12/18722	0.00644210369146757	0.0295283591663907	LYN/SORL1/GRN/EFNA1/PICALM	5
GO:1905666	regulation of protein localization to endosome	5/2053	12/18722	0.00644210369146757	0.0295283591663907	MSN/SORL1/RDX/DTX3L/EZR	5
GO:0010232	vascular transport	18/2053	88/18722	0.00649360052486706	0.0297416817932842	SLC2A3/LRP2/CD36/SLC2A1/SLC38A1/SLC29A1/GJA1/SLC6A6/FABP5/SLC1A5/SLC16A12/SLC16A1/SLC19A1/SLC13A3/SLC44A1/TFRC/INSR/SLC1A3	18
GO:0046633	alpha-beta T cell proliferation	10/2053	38/18722	0.0065091830996723	0.0297676056387453	HLA-A/PTPRC/LGALS9/HLA-E/TNFRSF14/CCR2/DOCK2/SYK/IRF1/IL18	10
GO:1901031	regulation of response to reactive oxygen species	10/2053	38/18722	0.0065091830996723	0.0297676056387453	LRRK2/CD36/MET/BMP7/DHFR/PAWR/TXN/PARK7/GCH1/TRAP1	10
GO:0071375	cellular response to peptide hormone stimulus	46/2053	290/18722	0.00655912403060629	0.0299731486547127	CYBA/LYN/SORL1/UCP2/JAK2/FBN1/NR4A2/PARP1/IL1B/GSTP1/STAT1/SOCS3/PRKDC/STAT6/NUCKS1/CSK/ZFP36L1/ATP2B1/PDK4/NR4A1/CDC6/STAT5A/PRKCB/KANK1/GNAI2/CCND3/CCNA2/STAT3/SMARCC1/CDK4/MYO1C/ASS1/GRB2/FOXO4/RHOQ/APEX1/SLC9A1/BCAR1/CSH1/IGF1R/GAB1/INSR/MYO5A/PTK2/PPAT/PPARG	46
GO:0072073	kidney epithelium development	25/2053	136/18722	0.00662054523354993	0.030230800153196	PECAM1/MEF2C/VEGFA/STAT1/MAGED1/CD24/RARA/BMP7/LAMA5/NOTCH1/TACSTD2/NOTCH2/AHI1/GATA3/PBX1/LGR4/YAP1/DLG1/GLI3/FOXC1/SMAD5/BASP1/IRX2/ASXL1/GPC3	25
GO:0062208	positive regulation of pattern recognition receptor signaling pathway	11/2053	44/18722	0.00670061732598924	0.0304831433219987	CYBA/TLR2/HMGB1/TLR1/OASL/TLR4/RSAD2/SLC15A3/IFI35/USP15/HSPA1A	11
GO:0150076	neuroinflammatory response	11/2053	44/18722	0.00670061732598924	0.0304831433219987	PTPRC/CCL3/TNFRSF1B/LRRK2/TNF/IL1B/GRN/ITGB1/TREM2/SPHK1/IL18	11
GO:0001961	positive regulation of cytokine-mediated signaling pathway	12/2053	50/18722	0.00670121100695272	0.0304831433219987	LAPTM5/CD74/CXCR4/CASP1/CD300LF/IRF7/PARP9/TREM2/AGPAT2/NLRC5/HSPA1A/PARP14	12
GO:0002639	positive regulation of immunoglobulin production	12/2053	50/18722	0.00670121100695272	0.0304831433219987	PTPRC/TGFB1/CD86/HLA-E/SASH3/STAT6/PHB2/MSH2/PHB/RIF1/TFRC/DNAJB9	12
GO:0007080	mitotic metaphase plate congression	12/2053	50/18722	0.00670121100695272	0.0304831433219987	CDT1/KPNB1/CDCA5/NUF2/KIF22/NDC80/EML4/NUDC/AURKB/CHMP4C/CDCA8/KIFC1	12
GO:0032967	positive regulation of collagen biosynthetic process	8/2053	27/18722	0.00675604524532592	0.0307086671325872	VIM/TGFB1/ARRB2/RUNX1/ENG/HDAC2/RGCC/SUCO	8
GO:1903321	negative regulation of protein modification by small protein conjugation or removal	19/2053	95/18722	0.00676102488035795	0.0307086671325872	TSPO/ISG15/TNFAIP3/ARRB2/RPS7/RPS3/RPL5/PPIA/RPL37/RPL23/MAD2L1/CHP1/FBXO5/SOX4/BAG2/DTX3L/PARK7/HSPA1A/RPS20	19
GO:1990542	mitochondrial transmembrane transport	20/2053	102/18722	0.00696545633500974	0.031613266270846	UCP2/HSPD1/SLC25A37/MPC2/SLC25A5/SLC25A3/SLC25A1/TOMM40/SLC25A36/SFXN3/SLC25A4/SFXN1/VDAC1/STOML2/AFG3L2/DNAJC19/MCUR1/MRS2/MPC1/SLC25A6	20
GO:0050688	regulation of defense response to virus	15/2053	69/18722	0.00697692641637872	0.0316413896434409	FGL2/PYCARD/LILRB1/IFIT1/TNFAIP3/STAT1/HSP90AA1/PARP9/AIM2/APOBEC3G/C1QBP/DTX3L/EIF2AK4/DDX58/HERC5	15
GO:0001892	embryonic placenta development	17/2053	82/18722	0.00699178466939489	0.0316609117104674	SPINT1/SPINT2/JUNB/PHLDA2/CEBPB/SOCS3/VASH1/BMP7/NR2F2/ZFP36L1/KRT8/EPAS1/ASCL2/GRB2/STK4/TRIM28/E2F7	17
GO:0009205	purine ribonucleoside triphosphate metabolic process	17/2053	82/18722	0.00699178466939489	0.0316609117104674	TMSB4X/TGFB1/GIMAP7/LRRK2/PARP1/RAN/TREM2/ALDOA/RHOA/STAT3/STOML2/NME4/IMPDH2/RHOQ/VCP/NME1/PRKAG2	17
GO:0007548	sex differentiation	44/2053	276/18722	0.00705572357418929	0.0319263510144312	TNFSF10/FLNA/NASP/RETN/VEGFA/LRP2/HMGB2/RRM1/CEBPB/LHFPL2/ADGRG1/ARRB2/PRDX4/SOD1/RARA/NR2F2/DHCR24/HSPA5/ICAM1/CCND1/CTSV/ASPM/RHOBTB3/MSH2/UBB/ADAMTS1/SF1/GATA3/PBX1/BRCA2/LGR4/MGST1/DNAJC19/IDH1/ARID5B/ERCC1/ING2/FOXC1/SMAD5/BASP1/TBX3/PLEKHA1/FANCA/TFAP2C	44
GO:0048754	branching morphogenesis of an epithelial tube	27/2053	151/18722	0.00717292655763046	0.0324322225665281	VEGFA/TNF/MAGED1/MET/CTSH/CTSZ/DAG1/BMP7/LAMA5/ENG/NOTCH1/PHB2/TACSTD2/NRP1/VDR/DLG5/PBX1/LRP5/COL4A1/LGR4/YAP1/DLG1/GLI3/STK4/MDK/TBX3/GPC3	27
GO:0048026	positive regulation of mRNA splicing, via spliceosome	7/2053	22/18722	0.00727199915076295	0.0327567529313646	HSPA8/PRDX6/NCL/RBMX/TRA2B/SNRNP70/PRPF19	7
GO:0060965	negative regulation of gene silencing by miRNA	7/2053	22/18722	0.00727199915076295	0.0327567529313646	TGFB1/NEAT1/TNF/LIN28B/STAT3/NCOR2/PPARG	7
GO:0071404	cellular response to low-density lipoprotein particle stimulus	7/2053	22/18722	0.00727199915076295	0.0327567529313646	FCER1G/ITGB2/CD9/CD36/SYK/ITGB1/PPARG	7
GO:0072574	hepatocyte proliferation	7/2053	22/18722	0.00727199915076295	0.0327567529313646	TNFAIP3/CEBPB/SULF2/RPS6KA1/NOTCH2/MDK/PTN	7
GO:0072575	epithelial cell proliferation involved in liver morphogenesis	7/2053	22/18722	0.00727199915076295	0.0327567529313646	TNFAIP3/CEBPB/SULF2/RPS6KA1/NOTCH2/MDK/PTN	7
GO:0007096	regulation of exit from mitosis	6/2053	17/18722	0.00733223643740623	0.032904576383274	PHB2/UBE2C/CDCA5/RGCC/ANLN/KNTC1	6
GO:0038065	collagen-activated signaling pathway	6/2053	17/18722	0.00733223643740623	0.032904576383274	JAK2/OSCAR/SYK/COL4A2/COL4A1/UBASH3B	6
GO:0042053	regulation of dopamine metabolic process	6/2053	17/18722	0.00733223643740623	0.032904576383274	ITGB2/ITGAM/NR4A2/COMT/PNKD/PARK7	6
GO:0042069	regulation of catecholamine metabolic process	6/2053	17/18722	0.00733223643740623	0.032904576383274	ITGB2/ITGAM/NR4A2/COMT/PNKD/PARK7	6
GO:0090713	immunological memory process	6/2053	17/18722	0.00733223643740623	0.032904576383274	HLA-DRA/HLA-DRB1/FGL2/TNFRSF14/CD46/BCL6	6
GO:0046902	regulation of mitochondrial membrane permeability	14/2053	63/18722	0.00735217377598664	0.0329693891299849	SLC25A5/HK2/BNIP3L/PMAIP1/STAT3/SLC25A4/HEBP2/CHCHD10/SLC9A1/HSPA1A/BAD/NMT1/BNIP3/DYNLT1	14
GO:0016570	histone modification	68/2053	463/18722	0.00748350371305201	0.0335332503945572	SPI1/JAK2/LRRK2/VEGFA/IL1B/DNMT1/CDK1/BCL6/VRK1/RTF1/MORF4L2/BRCA1/PRKCB/SET/EZH2/CAMK2D/CHEK1/JDP2/DDB1/HAT1/ISL1/BAZ1B/CCNA2/USP15/SUZ12/HDAC2/BRD7/SMYD2/GATA3/BRD4/BRCA2/POLE3/PARP2/USP3/KDM1B/PHB/DTX3L/EID1/USP22/KMT5A/PARK7/KMT2E/DPY30/TBL1X/CDK2/RNF8/ING2/AURKB/RIF1/ZNF451/PHF20/UHRF1/YEATS4/NTMT1/KDM6B/ACTL6A/LMNA/RPS6KA5/FBL/HUWE1/PWP1/UBE2N/BRCC3/PKN1/MBD3/ASXL1/RCOR1/NCAPG2	68
GO:0045685	regulation of glial cell differentiation	16/2053	76/18722	0.00749828635187831	0.0335744165009476	CXCR4/TNFRSF1B/TGFB1/TLR2/SPINT1/DAG1/CDK1/NOTCH1/TREM2/RHEB/HDAC2/IL6ST/ID2/MDK/PTN/PRPF19	16
GO:0010259	multicellular organism aging	9/2053	33/18722	0.00753020724990146	0.0335920026017909	LRRK2/SERP1/CTSV/MSH2/MSH6/SEC63/INPP5D/ERCC1/TFCP2L1	9
GO:0042558	pteridine-containing compound metabolic process	9/2053	33/18722	0.00753020724990146	0.0335920026017909	TYMS/GGH/DHFR/FOLR1/SLC19A1/GCH1/QDPR/SHMT1/MTR	9
GO:0050901	leukocyte tethering or rolling	9/2053	33/18722	0.00753020724990146	0.0335920026017909	TNF/ITGA4/PTAFR/CCR2/SELPLG/ITGB1/SPN/CX3CR1/SELL	9
GO:0061842	microtubule organizing center localization	9/2053	33/18722	0.00753020724990146	0.0335920026017909	SYNE2/MAD2L1/ASPM/PARD3/EZR/DLG1/DYNC1LI2/AKAP9/GPSM2	9
GO:1904031	positive regulation of cyclin-dependent protein kinase activity	9/2053	33/18722	0.00753020724990146	0.0335920026017909	EGFR/HSP90AB1/CKS1B/CDC6/CCND1/CCND3/CKS2/RGCC/CDKN1A	9
GO:0009259	ribonucleotide metabolic process	58/2053	385/18722	0.00766201358252242	0.0341545924926705	TMSB4X/TGFB1/UPP1/GIMAP7/LRRK2/HINT1/FBP1/PARP1/APP/KYNU/DPYD/SLC26A2/RAN/MPC2/ACSS1/TECR/TREM2/HK3/PDK4/PAICS/P2RX7/PDE4A/HK2/DDIT4/PPT1/SLC2A6/SULT1A1/NUDT8/ALDOA/SLC25A1/LDHA/RHOA/UMPS/STAT3/PNP/ARL2/ACSL4/GMPS/DHTKD1/TPST2/PMVK/PDHA1/STOML2/NME4/ADK/NUDT4/IMPDH2/RHOQ/DLG1/BAD/MPP1/AMPD3/INSR/VCP/NME1/PPAT/GAPDH/PRKAG2	58
GO:0009408	response to heat	21/2053	110/18722	0.00790770297014321	0.0351359678801125	CD14/LYN/TFEC/HSPD1/HMOX1/CXCL10/RBBP7/HSP90AA1/HSP90AB1/SOD1/PSIP1/TRPV2/HSPA6/TRPM2/HDAC2/TPR/YWHAE/HSPA1A/HSBP1L1/CDKN1A/VCP	21
GO:0045661	regulation of myoblast differentiation	12/2053	51/18722	0.00790847858147048	0.0351359678801125	TGFB1/MEF2C/TNF/CXCL10/MBNL3/NOTCH1/ZFP36L1/BTG1/ID3/TBX3/IL18/MAPK14	12
GO:0002701	negative regulation of production of molecular mediator of immune response	10/2053	39/18722	0.00791144876767201	0.0351359678801125	BST2/HLA-F/TGFB1/LILRB1/LILRB4/TNF/IRAK3/HMOX1/PRKDC/BCL6	10
GO:0034314	Arp2/3 complex-mediated actin nucleation	10/2053	39/18722	0.00791144876767201	0.0351359678801125	GMFG/WAS/ARPC3/ARPC5L/IQGAP2/ACTR2/ARPC4/ACTR3/ARPC1A/WASF2	10
GO:0036297	interstrand cross-link repair	10/2053	39/18722	0.00791144876767201	0.0351359678801125	NUCKS1/RAD51AP1/RAD51/MSH6/FANCD2/FANCL/ERCC1/RNF8/VCP/FANCA	10
GO:0072676	lymphocyte migration	22/2053	117/18722	0.0079880984858918	0.0353857497798179	AIF1/CCL3L3/CCL3/MSN/CCL4/PYCARD/MYO1G/ITGAL/TNFRSF14/CXCL16/APP/ITGA4/CCR2/CXCL10/IL27RA/ADAM8/PTK2B/GPR183/SPN/ICAM1/RHOA/GATA3	22
GO:0070830	bicellular tight junction assembly	15/2053	70/18722	0.00800143081291799	0.0353857497798179	PECAM1/MTDH/TNF/GPBAR1/CLDN4/CLDN7/GJA1/MARVELD3/PARD3/ARL2/MYO1C/TJP1/ECT2/DLG1/MPP7	15
GO:0002920	regulation of humoral immune response	11/2053	45/18722	0.00800897470016545	0.0353857497798179	PTPRC/TNF/IL1B/C3/CD46/PTPN6/TREM2/CD59/C1QBP/PHB/SERPING1	11
GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	11/2053	45/18722	0.00800897470016545	0.0353857497798179	GPX1/SOD2/JAK2/PARP1/P4HB/SOD1/PPIA/TREM2/MCL1/PARK7/TRAP1	11
GO:0035307	positive regulation of protein dephosphorylation	11/2053	45/18722	0.00800897470016545	0.0353857497798179	PTPRC/TGFB1/LILRB2/CD300A/JAK2/HSP90AB1/PPIA/CD33/SLC39A10/CALM2/PPP1R15A	11
GO:0071354	cellular response to interleukin-6	11/2053	45/18722	0.00800897470016545	0.0353857497798179	SPI1/JAK2/JAK1/SELPLG/IL6R/HAMP/ICAM1/STAT3/IL6ST/YAP1/PHB	11
GO:1904646	cellular response to amyloid-beta	11/2053	45/18722	0.00800897470016545	0.0353857497798179	TLR4/PARP1/CD36/APP/ITGA4/NAMPT/TLR6/TREM2/ICAM1/GJA1/IGF1R	11
GO:0009132	nucleoside diphosphate metabolic process	23/2053	124/18722	0.0080238940616051	0.0354255808459387	FBP1/APP/HK3/DTYMK/ENTPD1/P2RX7/HK2/DDIT4/SLC2A6/ALDOA/LDHA/STAT3/ARL2/DHTKD1/NME4/NUDT5/DLG1/BAD/MPP1/INSR/NME1/GAPDH/PRKAG2	23
GO:0030100	regulation of endocytosis	35/2053	211/18722	0.00830912720267262	0.036657914129438	CD14/NCKAP1L/B2M/LILRB1/CD300A/LRRK2/VEGFA/CD36/ARRB2/C3/LRPAP1/SYK/LGALS3/MCTP1/TREM2/BMP2K/PPT1/AAK1/APOC1/CD151/SPHK1/RIN3/AHI1/ITGAV/SDCBP/CD63/DGKD/CD2AP/NUMB/INSR/PICALM/PACSIN3/AP2M1/LDLRAP1/GPC3	35
GO:1903409	reactive oxygen species biosynthetic process	14/2053	64/18722	0.00848415353327659	0.0374025872150327	CYBA/NCF1/PAGE4/SOD2/ALOX5/TLR4/HSPD1/CD36/TLR6/SOD1/RHOA/STAT3/PARK7/TRAP1	14
GO:0007492	endoderm development	16/2053	77/18722	0.00852579469923247	0.0375034957444243	ITGB2/DUSP1/FN1/ITGA5/ITGA4/DUSP2/LAMB1/NOTCH1/ZFP36L1/COL4A2/LAMC1/RTF1/ITGB5/ITGAV/DUSP5/MMP15	16
GO:0010827	regulation of glucose transmembrane transport	16/2053	77/18722	0.00852579469923247	0.0375034957444243	TNF/IL1B/C3/MEF2A/HK2/PRKCB/FABP5/RAP1A/ASPSCR1/RHOQ/YES1/INSR/PEA15/MAPK14/PRKAG2/GPC3	16
GO:1901983	regulation of protein acetylation	16/2053	77/18722	0.00852579469923247	0.0375034957444243	SPI1/IL1B/CAMK1/BRCA1/HINT2/SET/CHEK1/ISL1/SOX4/HDAC2/BRD7/GATA3/EID1/PARK7/ZNF451/RPS6KA5	16
GO:0000470	maturation of LSU-rRNA	8/2053	28/18722	0.00856637465106943	0.0375718186450414	RPL7A/RPL35/NHP2/RPL10A/SNU13/MRPL1/RPL7/DDX18	8
GO:0006972	hyperosmotic response	8/2053	28/18722	0.00856637465106943	0.0375718186450414	SLC2A1/RCSD1/AKR1B1/XRCC5/XRCC6/ARHGEF2/EFHD1/PKN1	8
GO:0010714	positive regulation of collagen metabolic process	8/2053	28/18722	0.00856637465106943	0.0375718186450414	VIM/TGFB1/ARRB2/RUNX1/ENG/HDAC2/RGCC/SUCO	8
GO:0051503	adenine nucleotide transport	8/2053	28/18722	0.00856637465106943	0.0375718186450414	SLC25A5/LRRC8C/SLC29A1/GJA1/SLC25A4/SLC19A1/SLC25A17/SLC25A6	8
GO:0051047	positive regulation of secretion	48/2053	310/18722	0.00875375066298473	0.0383655982307585	S100A8/HLA-DRB1/ITGB2/CYBA/HLA-F/TGFB1/TLR2/EGFR/FGR/SPP1/JAK2/RETN/ITGAM/TLR4/IL1B/MYH10/PTAFR/WLS/GLUL/SYK/MPC2/SERP1/PPIA/TREM2/ADAM8/CD33/GJA1/GNAI2/TRPM2/SLC6A4/ISL1/SYT7/FRMD4A/SOX4/RGCC/SNX4/ACSL4/SDCBP/RAB3D/SCIN/KCNN4/PHPT1/EZR/BAD/PTGES/C1QTNF1/CD2AP/TM7SF3	48
GO:0006413	translational initiation	22/2053	118/18722	0.00882905126589512	0.0386673778068399	TNF/EIF1/RPS5/RPS17/RPS3/NPM1/RPL13A/EIF1AY/TPR/EIF5B/EIF2AK4/DDX1/EIF2AK1/EIF5/EIF3J/PPP1R15A/AGO2/DENR/EIF3A/EIF1AX/EIF4G1/EIF3L	22
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	13/2053	58/18722	0.0089218686096701	0.0390453768475716	S100A8/SKIL/RPS7/RPS3/SOD1/S100A9/UBB/PMAIP1/MCL1/SIAH1/FIS1/PARK7/BAD	13
GO:0045445	myoblast differentiation	17/2053	84/18722	0.00893771946943463	0.0390862367467987	LGALS1/TGFB1/MEF2C/TNF/CXCL10/MBNL3/NOTCH1/ZFP36L1/DTYMK/BTG1/EPAS1/ISL1/ID3/MBNL1/TBX3/IL18/MAPK14	17
GO:0072080	nephron tubule development	18/2053	91/18722	0.0092501549762347	0.0402871846797157	MEF2C/VEGFA/STAT1/MAGED1/CD24/LAMA5/NOTCH1/TACSTD2/NOTCH2/AHI1/GATA3/PBX1/LGR4/YAP1/DLG1/GLI3/IRX2/GPC3	18
GO:0007431	salivary gland development	9/2053	34/18722	0.00926543999885458	0.0402871846797157	TGFB1/TNF/TGM2/DAG1/BMP7/LAMA5/NRP1/TFCP2L1/PDGFA	9
GO:0034383	low-density lipoprotein particle clearance	9/2053	34/18722	0.00926543999885458	0.0402871846797157	CD36/HMOX1/CSK/TREM2/LIPA/KHSRP/CNPY2/MYLIP/LDLRAP1	9
GO:0035308	negative regulation of protein dephosphorylation	9/2053	34/18722	0.00926543999885458	0.0402871846797157	NCKAP1L/TNF/LGALS3/GNAI2/YWHAE/MASTL/FKBP1A/PPP1R15A/ENSA	9
GO:0043276	anoikis	9/2053	34/18722	0.00926543999885458	0.0402871846797157	ITGA5/ITGB1/NOTCH1/PDK4/MCL1/TFDP1/TLE1/PTK2/E2F1	9
GO:1990000	amyloid fibril formation	9/2053	34/18722	0.00926543999885458	0.0402871846797157	B2M/CD36/APP/PFDN5/TREM2/SIAH2/SIAH1/FKBP1A/PFDN1	9
GO:0045010	actin nucleation	12/2053	52/18722	0.00927948153789452	0.0402871846797157	GMFG/CORO1A/WAS/ARPC3/ARPC5L/IQGAP2/ACTR2/SCIN/ARPC4/ACTR3/ARPC1A/WASF2	12
GO:0048260	positive regulation of receptor-mediated endocytosis	12/2053	52/18722	0.00927948153789452	0.0402871846797157	B2M/VEGFA/ARRB2/C3/SYK/PPT1/AHI1/CD63/DGKD/INSR/AP2M1/LDLRAP1	12
GO:1903426	regulation of reactive oxygen species biosynthetic process	12/2053	52/18722	0.00927948153789452	0.0402871846797157	CYBA/PAGE4/SOD2/ALOX5/TLR4/HSPD1/CD36/TLR6/RHOA/STAT3/PARK7/TRAP1	12
GO:2000378	negative regulation of reactive oxygen species metabolic process	12/2053	52/18722	0.00927948153789452	0.0402871846797157	PAGE4/HSPD1/HK2/BRCA1/TFAP2A/RHOA/STAT3/ACP5/VDAC1/PARK7/BNIP3/TRAP1	12
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	19/2053	98/18722	0.00947560098426128	0.0407771362747058	CD74/CD44/PLAUR/GPX1/SOD2/LRRK2/HELLS/PPIA/MCL1/TRIAP1/PARK7/ARHGEF2/HSPA1A/ING2/TRAP1/RTKN2/NDUFA13/FIGNL1/URI1	19
GO:0002758	innate immune response-activating signal transduction	7/2053	23/18722	0.00948145349650411	0.0407771362747058	TYROBP/FCN1/CLEC7A/LYN/HCK/LILRA2/SYK	7
GO:0006929	substrate-dependent cell migration	7/2053	23/18722	0.00948145349650411	0.0407771362747058	PTPRC/FN1/ADAM8/NRP1/SDCBP/CD2AP/STK4	7
GO:0035994	response to muscle stretch	7/2053	23/18722	0.00948145349650411	0.0407771362747058	SLC8A1/FOS/NFKBIA/SLC9A1/DMD/PTK2/MAPK14	7
GO:0060396	growth hormone receptor signaling pathway	7/2053	23/18722	0.00948145349650411	0.0407771362747058	LYN/JAK2/STAT6/STAT5A/STAT3/CSH1/PTK2	7
GO:0072576	liver morphogenesis	7/2053	23/18722	0.00948145349650411	0.0407771362747058	TNFAIP3/CEBPB/SULF2/RPS6KA1/NOTCH2/MDK/PTN	7
GO:0007183	SMAD protein complex assembly	5/2053	13/18722	0.00953389643321684	0.0407771362747058	TGFB1/PARP1/LDLRAD4/FKBP1A/EID2	5
GO:0009143	nucleoside triphosphate catabolic process	5/2053	13/18722	0.00953389643321684	0.0407771362747058	SAMHD1/DUT/NUDT15/DCTPP1/SMPDL3A	5
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	5/2053	13/18722	0.00953389643321684	0.0407771362747058	PRDX2/TNFAIP3/LILRA2/CARD16/TRIB1	5
GO:0032494	response to peptidoglycan	5/2053	13/18722	0.00953389643321684	0.0407771362747058	C5AR1/IRAK3/TREM2/IRF5/MYD88	5
GO:0036005	response to macrophage colony-stimulating factor	5/2053	13/18722	0.00953389643321684	0.0407771362747058	CSF1R/TLR2/TLR4/TREM2/DOK1	5
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	5/2053	13/18722	0.00953389643321684	0.0407771362747058	CSF1R/TLR2/TLR4/TREM2/DOK1	5
GO:0043379	memory T cell differentiation	5/2053	13/18722	0.00953389643321684	0.0407771362747058	HLA-DRA/HLA-DRB1/FGL2/CD46/BCL6	5
GO:0060347	heart trabecula formation	5/2053	13/18722	0.00953389643321684	0.0407771362747058	ADAMTS1/FHL2/FKBP1A/TGFBR3/ADGRG6	5
GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway	5/2053	13/18722	0.00953389643321684	0.0407771362747058	TNFAIP3/TLR4/SLC15A3/BIRC3/HSPA1A	5
GO:0071801	regulation of podosome assembly	5/2053	13/18722	0.00953389643321684	0.0407771362747058	MSN/LCP1/HCK/TNF/RHOA	5
GO:1900115	extracellular regulation of signal transduction	5/2053	13/18722	0.00953389643321684	0.0407771362747058	FBN2/FBN1/LRPAP1/CD46/LTBP1	5
GO:1900116	extracellular negative regulation of signal transduction	5/2053	13/18722	0.00953389643321684	0.0407771362747058	FBN2/FBN1/LRPAP1/CD46/LTBP1	5
GO:1903054	negative regulation of extracellular matrix organization	5/2053	13/18722	0.00953389643321684	0.0407771362747058	TNFRSF1B/TGFB1/CST3/DPP4/NOTCH1	5
GO:0034122	negative regulation of toll-like receptor signaling pathway	10/2053	40/18722	0.00953505369890204	0.0407771362747058	LYN/CD300A/TNFAIP3/IRAK3/CD300LF/ARRB2/LILRA2/TLR6/TREM2/LGR4	10
GO:0150077	regulation of neuroinflammatory response	10/2053	40/18722	0.00953505369890204	0.0407771362747058	PTPRC/CCL3/TNFRSF1B/LRRK2/TNF/IL1B/GRN/TREM2/SPHK1/IL18	10
GO:0009896	positive regulation of catabolic process	71/2053	492/18722	0.00955699699854894	0.0408418675151664	LAPTM5/MSN/TNFRSF1B/ZFP36/MTDH/ZFP36L2/SORL1/TRIM22/HMGB1/LRRK2/LRP2/OAZ1/TNF/TNFAIP3/IL1B/APP/HMOX1/PLK3/PABPC1/HSP90AA1/SLC25A5/LIN28B/ZFP36L1/TREM2/TNFSF12/ADAM8/PTK2B/HNRNPR/HAMP/P2RX7/BNIP3L/PHB2/PSMC3/BTG2/GJA1/DTL/EXOSC8/TRIB1/DDB1/RDX/BARD1/PSMC1/SLC25A4/HNRNPD/RALB/KHSRP/BAG2/SVIP/TRIM38/VDAC1/PSMC2/DTX3L/MAGEF1/TMTC3/SCOC/PARK7/EZR/HSPA1A/BAD/BNIP3/AGO2/INSR/VCP/PLK2/GABARAP/PTK2/PACSIN3/HUWE1/NDUFA13/MYLIP/GPC3	71
GO:0032231	regulation of actin filament bundle assembly	20/2053	105/18722	0.00962564771866051	0.0410767327965598	PLEK/FLNA/WAS/GPR65/STMN1/PTGER4/MET/ID1/CCDC88A/TACSTD2/S100A10/RDX/NRP1/RHOA/RGCC/TJP1/FERMT2/WASF2/PFN1/SLC9A1	20
GO:0040029	regulation of gene expression, epigenetic	20/2053	105/18722	0.00962564771866051	0.0410767327965598	XIST/SPI1/GPX1/KLF2/IFI16/HELLS/DNMT1/CDCA4/KCNQ1/BRCA1/EZH2/CHEK1/TPR/POLE3/KDM1B/TRIM28/MBD2/MBD3/SMARCA5/TFAP2C	20
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	16/2053	78/18722	0.00966247764175795	0.041175330859764	LAPTM5/S100A8/PYCARD/JAK2/TNF/HSPD1/CTSH/S100A9/HSPE1/NLRP12/PMAIP1/NLRP1/CASP8AP2/BAD/VCP/PPARG	16
GO:0090559	regulation of membrane permeability	16/2053	78/18722	0.00966247764175795	0.041175330859764	LAPTM5/SLC25A5/HK2/BNIP3L/PMAIP1/STAT3/SLC25A4/JAM3/HEBP2/CHCHD10/SLC9A1/HSPA1A/BAD/NMT1/BNIP3/DYNLT1	16
GO:0016072	rRNA metabolic process	38/2053	236/18722	0.00995875678074729	0.0422862531212633	RPS21/ISG20/PA2G4/RPS17/RPS7/RPS27/PRKDC/RPS16/RPS14/RPL5/RPL7A/POP7/EXOSC8/RPS19/NOP56/RPL35/NHP2/RPL10A/NOP58/RPL14/RBFA/RPS6/RPS8/SNU13/MRPL1/RPL7/IMP3/WDR18/SBDS/KRR1/BRIX1/WBP11/RPS25/DDX18/FBL/PWP1/MRTO4/BMS1	38
GO:0002544	chronic inflammatory response	6/2053	18/18722	0.00999365115432524	0.0422862531212633	S100A8/TNF/TNFAIP3/S100A9/GJA1/PTGES	6
GO:0002643	regulation of tolerance induction	6/2053	18/18722	0.00999365115432524	0.0422862531212633	HLA-B/LILRB2/HAVCR2/LILRB4/HMGB1/IRAK3	6
GO:0009125	nucleoside monophosphate catabolic process	6/2053	18/18722	0.00999365115432524	0.0422862531212633	TYMP/UPP1/DPYD/PNP/AMPD3/DNPH1	6
GO:0046851	negative regulation of bone remodeling	6/2053	18/18722	0.00999365115432524	0.0422862531212633	TNFAIP3/CSK/HAMP/P2RX7/INPP5D/UBASH3B	6
GO:0051382	kinetochore assembly	6/2053	18/18722	0.00999365115432524	0.0422862531212633	CENPW/CENPF/CENPN/CENPK/CENPH/KNTC1	6
GO:0055070	copper ion homeostasis	6/2053	18/18722	0.00999365115432524	0.0422862531212633	APP/SCO2/MT2A/ANKRD9/COMMD1/SCO1	6
GO:0150078	positive regulation of neuroinflammatory response	6/2053	18/18722	0.00999365115432524	0.0422862531212633	CCL3/LRRK2/TNF/IL1B/TREM2/IL18	6
GO:1900225	regulation of NLRP3 inflammasome complex assembly	6/2053	18/18722	0.00999365115432524	0.0422862531212633	GBP5/TLR4/CD36/TLR6/TREM2/MYD88	6
GO:1904872	regulation of telomerase RNA localization to Cajal body	6/2053	18/18722	0.00999365115432524	0.0422862531212633	NHP2/TCP1/CCT6A/CCT2/CCT4/CCT8	6
GO:0006816	calcium ion transport	62/2053	422/18722	0.0102106396080378	0.0431739518310264	TSPO/PTPRC/CXCR4/CORO1A/CCL3/CYBA/CCL4/CD84/LYN/LILRB2/SLC8A1/LILRB1/CD4/CCR1/HOMER3/ARRB2/CXCL10/LILRA2/ORAI2/PTPN6/LILRA5/LGALS3/ATP2B1/CATSPER1/PTK2B/IL16/TRPV2/P2RX7/ICAM1/CD33/VMP1/TSPAN13/CYSLTR1/PRKCB/GJA1/CAMK2D/KCNE3/GNAI2/TRPM2/RHOA/CALM2/C4orf3/MCOLN3/VDR/ITGAV/KCNN4/VDAC1/STOML2/AFG3L2/YWHAE/SLC9A1/CAMK2G/BEST1/MCUR1/DMD/FKBP1A/PMPCB/UBASH3B/PACSIN3/EPB41/HOMER1/SLC3A2	62
GO:1903532	positive regulation of secretion by cell	44/2053	282/18722	0.0102571240080286	0.0433399605973039	HLA-DRB1/ITGB2/HLA-F/TGFB1/TLR2/EGFR/FGR/SPP1/JAK2/RETN/ITGAM/TLR4/IL1B/MYH10/PTAFR/WLS/GLUL/SYK/MPC2/SERP1/PPIA/TREM2/ADAM8/CD33/GJA1/TRPM2/SLC6A4/ISL1/SYT7/FRMD4A/SOX4/RGCC/SNX4/ACSL4/SDCBP/RAB3D/KCNN4/PHPT1/EZR/BAD/PTGES/C1QTNF1/CD2AP/TM7SF3	44
GO:0043484	regulation of RNA splicing	26/2053	148/18722	0.0103057353360064	0.0435147164081901	CELF2/FUS/SRSF2/MBNL3/NPM1/HNRNPA1/HSPA8/C1QBP/SF1/PRDX6/RBM39/MAGOH/SRSF10/ESRP1/ZNF326/SRPK1/NCL/MBNL1/SRSF7/HSPA1A/RBMX/TRA2B/SNRNP70/TIA1/PRPF19/SRSF4	26
GO:0002820	negative regulation of adaptive immune response	13/2053	59/18722	0.0103233437402286	0.0435278021372955	PTPRC/HLA-F/NCKAP1L/HAVCR2/LILRB1/LILRB4/TNFRSF14/CD46/IL27RA/PTPN6/IL4I1/SAMSN1/BCL6	13
GO:0035306	positive regulation of dephosphorylation	13/2053	59/18722	0.0103233437402286	0.0435278021372955	PTPRC/PLEK/TGFB1/LILRB2/MEF2C/CD300A/JAK2/HSP90AB1/PPIA/CD33/SLC39A10/CALM2/PPP1R15A	13
GO:0031058	positive regulation of histone modification	18/2053	92/18722	0.0103531843846823	0.0436229679129874	LRRK2/VEGFA/IL1B/DNMT1/BCL6/RTF1/BRCA1/JDP2/ISL1/BRD7/GATA3/BRD4/KMT2E/ING2/RIF1/LMNA/RPS6KA5/UBE2N	18
GO:0008584	male gonad development	25/2053	141/18722	0.0104586980568129	0.0440366233971071	TNFSF10/FLNA/NASP/LRP2/HMGB2/RRM1/ADGRG1/PRDX4/RARA/ICAM1/CCND1/CTSV/ASPM/RHOBTB3/MSH2/UBB/SF1/GATA3/MGST1/ARID5B/ERCC1/ING2/PLEKHA1/FANCA/TFAP2C	25
GO:0006090	pyruvate metabolic process	20/2053	106/18722	0.0106748873479255	0.0449153745354509	FBP1/APP/SDS/MPC2/HK3/PDK4/P2RX7/HK2/DDIT4/SLC2A6/ALDOA/LDHA/STAT3/ARL2/DHTKD1/VDAC1/PDHA1/INSR/GAPDH/PRKAG2	20
GO:0010458	exit from mitosis	8/2053	29/18722	0.0107160964353299	0.0449941067963467	PHB2/UBE2C/CDCA5/UBE2S/RGCC/ANLN/EPS8/KNTC1	8
GO:0015868	purine ribonucleotide transport	8/2053	29/18722	0.0107160964353299	0.0449941067963467	SLC25A5/LRRC8C/SLC29A1/GJA1/SLC25A4/SLC19A1/SLC25A17/SLC25A6	8
GO:1903902	positive regulation of viral life cycle	8/2053	29/18722	0.0107160964353299	0.0449941067963467	HLA-DRB1/LGALS1/CD74/LGALS9/CD4/P4HB/DDB1/TRIM38	8
GO:0044106	cellular amine metabolic process	21/2053	113/18722	0.0107290590985276	0.0450170311826335	ITGB2/SLC7A7/ITGAM/OAZ1/NR4A2/KYNU/SAT1/IL4I1/ALDH7A1/COMT/PNKD/SULT1A1/AKR1B1/EPAS1/SMS/GATA3/SRM/PARK7/GCH1/SAT2/SLC44A1	21
GO:0009150	purine ribonucleotide metabolic process	55/2053	368/18722	0.0107523329550375	0.0450831570441825	TMSB4X/TGFB1/GIMAP7/LRRK2/HINT1/FBP1/PARP1/APP/KYNU/SLC26A2/RAN/MPC2/ACSS1/TECR/TREM2/HK3/PDK4/PAICS/P2RX7/PDE4A/HK2/DDIT4/PPT1/SLC2A6/SULT1A1/NUDT8/ALDOA/SLC25A1/LDHA/RHOA/STAT3/PNP/ARL2/ACSL4/GMPS/DHTKD1/TPST2/PMVK/PDHA1/STOML2/NME4/ADK/NUDT4/IMPDH2/RHOQ/DLG1/BAD/MPP1/AMPD3/INSR/VCP/NME1/PPAT/GAPDH/PRKAG2	55
GO:0008347	glial cell migration	12/2053	53/18722	0.0108282257400756	0.0453063838496885	TSPO/CCL3/CD9/ADGRG1/CCR2/LAMB1/TREM2/GPR183/IDH2/CX3CR1/GLI3/HEXB	12
GO:0034381	plasma lipoprotein particle clearance	12/2053	53/18722	0.0108282257400756	0.0453063838496885	MSR1/CD36/HMOX1/LRPAP1/CSK/TREM2/APOC1/LIPA/KHSRP/CNPY2/MYLIP/LDLRAP1	12
GO:0071320	cellular response to cAMP	12/2053	53/18722	0.0108282257400756	0.0453063838496885	SLC8A1/AQP9/APP/PTAFR/ZFP36L1/KCNQ1/HSPA5/ASS1/RAP1A/APEX1/EZR/AKAP9	12
GO:0014706	striated muscle tissue development	57/2053	384/18722	0.0109329090588986	0.0457125117445237	TGFB1/SLC8A1/MEF2C/VAMP5/FOS/GPX1/VEGFA/LRP2/DSP/HIVEP3/ARRB2/RUNX1/GPCPD1/MEF2A/RARA/CDK1/BMP7/ITGB1/CENPF/ENG/NOTCH1/NR2F2/CALR/NR4A1/HAMP/DSG2/BTG2/GJA1/GJA5/UQCC2/ISL1/RHOA/NOTCH2/MYL6/CACYBP/YAP1/PARP2/KLF5/MSX2/OBSL1/RGS2/SLC9A1/NDUFV2/GPC1/FHL2/DMD/FKBP1A/ID2/ATF3/FOXC1/TGFBR3/KDM6B/LMNA/SMAD5/TBX3/HOMER1/MAPK14	57
GO:0045055	regulated exocytosis	37/2053	230/18722	0.011026507158585	0.0460717569300209	ITGB2/CORO1A/CCL3/PLEK/HLA-F/SPI1/LGALS9/NCKAP1L/CD84/LYN/LAT2/CD300A/HCK/RAC2/FGR/LRRK2/ITGAM/PTAFR/HMOX1/STXBP2/CCR2/ADGRE2/PRAM1/BTK/STX11/SYK/NOTCH1/PRKCB/GNAI2/SYT7/SNX4/RAB3D/SCIN/RAP1A/ANXA3/CHRNA5/S100A13	37
GO:0072521	purine-containing compound metabolic process	61/2053	416/18722	0.0112016359642067	0.0466476019678915	TMSB4X/TGFB1/SAMHD1/GIMAP7/LRRK2/HINT1/FBP1/PARP1/APP/KYNU/DPYD/SLC26A2/RAN/MPC2/ACSS1/TECR/TREM2/HK3/PDK4/PAICS/P2RX7/PDE4A/HK2/DDIT4/PPT1/SLC2A6/SULT1A1/NUDT8/ALDOA/SLC25A1/LDHA/RHOA/MTAP/STAT3/NUDT15/PNP/ARL2/ACSL4/GMPS/DHTKD1/TPST2/PMVK/PDHA1/STOML2/NME4/ADK/NUDT4/IMPDH2/RHOQ/DLG1/BAD/MPP1/AMPD3/SHMT1/INSR/VCP/NME1/DNPH1/PPAT/GAPDH/PRKAG2	61
GO:0042311	vasodilation	11/2053	47/18722	0.011212351527938	0.0466476019678915	GPX1/EGFR/SOD2/KLF2/SOD1/GJA1/KCNMB1/GJA5/ADRB1/RGS2/GCH1	11
GO:0045581	negative regulation of T cell differentiation	11/2053	47/18722	0.011212351527938	0.0466476019678915	FGL2/CD74/LILRB4/HMGB1/PRDX2/RUNX1/BCL6/IRF1/RUNX3/GLI3/MDK	11
GO:0072583	clathrin-dependent endocytosis	11/2053	47/18722	0.011212351527938	0.0466476019678915	ITGA4/SIGLEC1/BMP2K/AAK1/ITSN2/CLTA/FNBP1L/DGKD/PICALM/AP2M1/AP2A2	11
GO:1900744	regulation of p38MAPK cascade	11/2053	47/18722	0.011212351527938	0.0466476019678915	NCF1/SPI1/DUSP1/VEGFA/IL1B/GADD45B/TREM2/SPHK1/EZR/DLG1/MAP3K4	11
GO:0051592	response to calcium ion	26/2053	149/18722	0.0112187482732779	0.0466476019678915	TXNIP/MEF2C/DUSP1/FOS/EGFR/ALOX5AP/JUNB/FUS/MEF2A/PTK2B/HSPA5/CCND1/FOSB/CAMK2D/KCNMB1/TRPM2/RASGRP2/CALM2/SYT7/HNRNPD/CACYBP/ECT2/BAD/PTGES/HOMER1/SEC31A	26
GO:1905039	carboxylic acid transmembrane transport	26/2053	149/18722	0.0112187482732779	0.0466476019678915	SLC7A7/SLC16A3/LRP2/AQP9/CD36/SLC2A1/SLC38A1/MPC2/ITGB1/LRRC8C/SLC6A6/SLC25A1/SLC1A5/SFXN3/SLC16A1/FOLR1/SLC19A1/SFXN1/RGS2/SLC13A3/SLC7A6/SLC38A9/MPC1/SLC38A6/SLC3A2/SLC1A3	26
GO:0000731	DNA synthesis involved in DNA repair	9/2053	35/18722	0.0112864021788252	0.0468639536837032	PCNA/RFC3/DTL/USP10/POLD3/POLA1/POLD4/VCP/POLE2	9
GO:0046640	regulation of alpha-beta T cell proliferation	9/2053	35/18722	0.0112864021788252	0.0468639536837032	HLA-A/PTPRC/LGALS9/HLA-E/TNFRSF14/CCR2/SYK/IRF1/IL18	9
GO:1905521	regulation of macrophage migration	10/2053	41/18722	0.0114009285586591	0.0473067575048094	CCL3/CSF1R/C5AR1/CD9/C3AR1/TREM2/PTK2B/CX3CR1/MDK/PTK2	10
GO:0050680	negative regulation of epithelial cell proliferation	28/2053	164/18722	0.0116744541560398	0.0484082411446019	TGFB1/B2M/MEF2C/ALOX5/TNF/SERPINF1/STAT1/MAGED1/VASH1/NR2F2/PHB2/FLT1/CDKN1C/GJA1/RUNX3/ISL1/MARVELD3/SUZ12/RGCC/VDR/GATA3/BRCA2/CDK6/DLG1/TGFBR3/PTN/PPARG/GPC3	28
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	23/2053	128/18722	0.0117014541853594	0.0484866886133677	ZEB2/TGFB1/PEG10/SKIL/FBN2/FBN1/HSP90AB1/NREP/ENG/HSPA5/LDLRAD4/CDKN1C/FERMT1/LTBP1/FOLR1/SDCBP/HSPA1A/FKBP1A/ING2/ZNF451/TGFBR3/EID2/PPARG	23
GO:0045807	positive regulation of endocytosis	19/2053	100/18722	0.0117269673129366	0.0485588708610212	CD14/NCKAP1L/B2M/LRRK2/VEGFA/CD36/ARRB2/C3/SYK/TREM2/PPT1/CD151/AHI1/CD63/DGKD/INSR/AP2M1/LDLRAP1/GPC3	19
GO:0010632	regulation of epithelial cell migration	45/2053	292/18722	0.0117736684343631	0.0487186280042612	TMSB4X/TGFB1/MEF2C/HMGB1/KLF4/VEGFA/TNF/SERPINF1/HMOX1/GRN/MET/GLIPR2/NRP2/CTSH/VASH1/GLUL/SEMA4A/NOTCH1/NR2F2/CALR/PTK2B/EMP2/STAT5A/RRAS/HBEGF/TACSTD2/NRP1/RHOA/CIB1/MARVELD3/RGCC/GATA3/PLPP3/EFNA1/RAB25/ANXA3/PFN1/SP100/BCAR1/CORO1C/RHOB/PLK2/PTN/PTK2/PPARG	45
GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	13/2053	60/18722	0.0118903383337195	0.0491336294781799	OASL/TNFAIP3/TLR4/IRF7/NFKBIA/PHB2/SLC15A3/BIRC3/C1QBP/USP15/PHB/HSPA1A/DDX58	13
GO:0006289	nucleotide-excision repair	13/2053	60/18722	0.0118903383337195	0.0491336294781799	HMGB1/RPA3/RPA2/DDB1/POLD3/POLR2I/BRCA2/PNKP/HMGN1/RPA1/COMMD1/ERCC1/RAD23B	13
GO:0001783	B cell apoptotic process	7/2053	24/18722	0.012143637363057	0.0498712006696384	CD74/LYN/BTK/BCL6/SLC39A10/AURKB/PKN1	7
GO:0010155	regulation of proton transport	7/2053	24/18722	0.012143637363057	0.0498712006696384	TMSB4X/PHB2/CHP1/PARK7/TCIRG1/ACTN4/COX17	7
GO:0043302	positive regulation of leukocyte degranulation	7/2053	24/18722	0.012143637363057	0.0498712006696384	ITGB2/HLA-F/FGR/ITGAM/PTAFR/SYK/SNX4	7
GO:0060149	negative regulation of posttranscriptional gene silencing	7/2053	24/18722	0.012143637363057	0.0498712006696384	TGFB1/NEAT1/TNF/LIN28B/STAT3/NCOR2/PPARG	7
GO:0060561	apoptotic process involved in morphogenesis	7/2053	24/18722	0.012143637363057	0.0498712006696384	TNFRSF1B/SPI1/BMP7/NOTCH1/VDR/LRP5/FOXC1	7
GO:0060967	negative regulation of gene silencing by RNA	7/2053	24/18722	0.012143637363057	0.0498712006696384	TGFB1/NEAT1/TNF/LIN28B/STAT3/NCOR2/PPARG	7
GO:0071378	cellular response to growth hormone stimulus	7/2053	24/18722	0.012143637363057	0.0498712006696384	LYN/JAK2/STAT6/STAT5A/STAT3/CSH1/PTK2	7
GO:1901984	negative regulation of protein acetylation	7/2053	24/18722	0.012143637363057	0.0498712006696384	SPI1/BRCA1/HINT2/SET/HDAC2/PARK7/ZNF451	7
GO:2000209	regulation of anoikis	7/2053	24/18722	0.012143637363057	0.0498712006696384	ITGA5/ITGB1/NOTCH1/PDK4/MCL1/TLE1/PTK2	7
GO:1903825	organic acid transmembrane transport	26/2053	150/18722	0.0121961035813447	0.0500524086785693	SLC7A7/SLC16A3/LRP2/AQP9/CD36/SLC2A1/SLC38A1/MPC2/ITGB1/LRRC8C/SLC6A6/SLC25A1/SLC1A5/SFXN3/SLC16A1/FOLR1/SLC19A1/SFXN1/RGS2/SLC13A3/SLC7A6/SLC38A9/MPC1/SLC38A6/SLC3A2/SLC1A3	26
GO:0009791	post-embryonic development	16/2053	80/18722	0.0122943326010903	0.0504210496285315	EFEMP1/KLF4/VEGFA/FBN1/NR4A2/C12orf57/SERP1/CCDC47/GATA3/ATF5/HMGN1/ARID5B/ERCC1/AGO2/PLEKHA1/MYO7A	16
GO:0016049	cell growth	69/2053	482/18722	0.0125019126035035	0.0512373467356702	S100A8/CXCR4/BST2/CYBA/TGFB1/FN1/EGFR/SPP1/VEGFA/FBP1/CXCL16/APP/ITGA4/SGK1/RBBP7/NRP2/HSP90AA1/HSP90AB1/ITGB1/ALCAM/S100A9/SEMA4A/BCL6/ARHGAP4/NPM1/CDA/PTK2B/TMEM97/HAMP/TRPV2/SEMA6A/PPT1/CHPT1/GJA1/HBEGF/CAMK2D/BTG1/ITSN2/NRP1/SPHK1/RASGRP2/RHOA/CIB1/RPS6KA1/GOLGA4/TWF2/SDCBP/SEMA6D/SMARCA2/PARP2/CDKN2A/NET1/PHB/EIF2AK4/RGS2/SLC9A1/BCAR1/VCL/EI24/HSPA1A/CDKN1A/PAK6/DNPH1/NDUFA13/EIF4G1/CLSTN1/DCBLD2/COBL/URI1	69
GO:0035065	regulation of histone acetylation	12/2053	54/18722	0.0125689309650282	0.0514768503687161	SPI1/IL1B/BRCA1/SET/CHEK1/ISL1/BRD7/GATA3/EID1/PARK7/ZNF451/RPS6KA5	12
GO:0010594	regulation of endothelial cell migration	37/2053	232/18722	0.012580458636606	0.0514889166573235	TMSB4X/TGFB1/MEF2C/HMGB1/KLF4/VEGFA/TNF/SERPINF1/HMOX1/GRN/MET/NRP2/VASH1/GLUL/SEMA4A/NOTCH1/NR2F2/CALR/PTK2B/EMP2/STAT5A/RRAS/NRP1/RHOA/CIB1/RGCC/GATA3/PLPP3/EFNA1/ANXA3/SP100/BCAR1/RHOB/PLK2/PTN/PTK2/PPARG	37
GO:0050796	regulation of insulin secretion	28/2053	165/18722	0.0126321083301135	0.0516650647448406	HLA-DRB1/UCP2/JAK2/ALOX5/TNF/IL1B/GLUL/MPC2/SERP1/DPP4/GJA1/HMGN3/UQCC2/TRPM2/KLF7/ISL1/SYT7/SOX4/HADH/ACSL4/SLC16A1/LRP5/PHPT1/BAD/TCIRG1/MIDN/ENSA/TM7SF3	28
GO:0150104	transport across blood-brain barrier	17/2053	87/18722	0.0126424505215606	0.0516721410962965	SLC2A3/LRP2/CD36/SLC2A1/SLC38A1/SLC29A1/SLC6A6/FABP5/SLC1A5/SLC16A12/SLC16A1/SLC19A1/SLC13A3/SLC44A1/TFRC/INSR/SLC1A3	17
GO:0010517	regulation of phospholipase activity	14/2053	67/18722	0.0127207547918843	0.0519567928872063	C5AR1/CD86/EGFR/PTAFR/S1PR4/PLCB2/GNA15/PHB2/FLT1/PPT1/HRAS/PHB/RGS2/ARL1	14
GO:0060537	muscle tissue development	59/2053	403/18722	0.0128411980753547	0.0524130533687946	TGFB1/SLC8A1/MEF2C/VAMP5/FOS/GPX1/VEGFA/LRP2/DSP/CSRP2/HIVEP3/ARRB2/RUNX1/GPCPD1/MEF2A/RARA/CDK1/BMP7/ITGB1/CENPF/ENG/NOTCH1/NR2F2/CALR/NR4A1/HAMP/DSG2/BTG2/GJA1/GJA5/UQCC2/ISL1/RHOA/NOTCH2/MYL6/CACYBP/YAP1/PARP2/KLF5/MSX2/OBSL1/RGS2/SLC9A1/NDUFV2/DLG1/GPC1/FHL2/DMD/FKBP1A/ID2/ATF3/FOXC1/TGFBR3/KDM6B/LMNA/SMAD5/TBX3/HOMER1/MAPK14	59
GO:0046939	nucleotide phosphorylation	19/2053	101/18722	0.0130017559016181	0.0530323150303935	FBP1/APP/HK3/DTYMK/P2RX7/HK2/DDIT4/SLC2A6/ALDOA/LDHA/STAT3/ARL2/DHTKD1/PNKP/NME4/INSR/NME1/GAPDH/PRKAG2	19
GO:0022411	cellular component disassembly	64/2053	443/18722	0.0130326465761573	0.0531089078098316	CTSS/TSPO/PLEK/LCP1/TGFB1/CAPG/CST3/STMN1/ITGAM/TNF/IRAK3/C3/PLK3/TOP2A/CDK1/SLC25A5/DPP4/DSTN/SUPT16H/TREM2/C1QA/RPL23/ADAM8/VRK1/LAMC1/CTSV/VMP1/HK2/PRKCB/DDIT4/BNIP3L/PHB2/SET/CX3CR1/HSPA8/RDX/CIB1/TPX2/HMGA1/CKAP2/SLC25A4/SMARCC1/TWF2/SCIN/MID1IP1/SPTBN1/VDAC1/VPS13C/FIS1/EPS8/PARK7/ARHGEF2/IGF1R/BNIP3/DENR/LIMA1/INSR/VCP/GABARAP/MMP15/TRIOBP/CFL1/HUWE1/WIPI2	64
GO:0007173	epidermal growth factor receptor signaling pathway	20/2053	108/18722	0.0130470883519486	0.0531089078098316	NCF1/TGFB1/PLAUR/EFEMP1/EGFR/IFI6/PTK2B/RHBDF2/CCDC88A/HBEGF/GRB2/RASSF2/DGKD/BCAR1/MVP/GAB1/VPS25/PTPN3/PTK2/RPS6KA5	20
GO:0140053	mitochondrial gene expression	20/2053	108/18722	0.0130470883519486	0.0531089078098316	TFAM/MRPL12/C1QBP/IARS2/UQCC2/MRPS34/MRPS15/MRPL16/MRPL51/TSFM/MRPL57/CHCHD10/MRPL2/MRPS6/MRPL43/CHCHD1/MALSU1/LRPPRC/MRPL47/MRPS21	20
GO:0007623	circadian rhythm	34/2053	210/18722	0.0130969767271939	0.0531724560341074	EGFR/TYMS/NAMPT/NR2F6/MAGED1/PRKDC/TOP2A/CLDN4/CDK1/HNRNPR/ID1/EZH2/DDB1/SLC6A4/ADRB1/SIAH2/HDAC2/HNRNPD/ATF5/CDK4/BHLHE40/ASS1/LGR4/ID3/ID4/GNA11/IMPDH2/JUN/TIMELESS/ID2/BHLHE41/GFPT1/HUWE1/PPARG	34
GO:0030261	chromosome condensation	11/2053	48/18722	0.013141478512953	0.0531724560341074	TOP2A/CDK1/SMC2/NUSAP1/SMC4/CDCA5/NCAPD3/NCAPH/KMT5A/NCAPG/NCAPG2	11
GO:0090199	regulation of release of cytochrome c from mitochondria	11/2053	48/18722	0.013141478512953	0.0531724560341074	TNFSF10/PYCARD/PLAUR/GPX1/ARRB2/PMAIP1/TRIAP1/PDCD5/BAD/BNIP3/LMNA	11
GO:0006099	tricarboxylic acid cycle	8/2053	30/18722	0.0132398133338935	0.0531724560341074	IDH2/FH/DHTKD1/PDHA1/MDH1/IDH1/SUCLG1/SDHA	8
GO:0007202	activation of phospholipase C activity	8/2053	30/18722	0.0132398133338935	0.0531724560341074	C5AR1/CD86/EGFR/S1PR4/PLCB2/GNA15/PHB2/PHB	8
GO:0015865	purine nucleotide transport	8/2053	30/18722	0.0132398133338935	0.0531724560341074	SLC25A5/LRRC8C/SLC29A1/GJA1/SLC25A4/SLC19A1/SLC25A17/SLC25A6	8
GO:0043032	positive regulation of macrophage activation	8/2053	30/18722	0.0132398133338935	0.0531724560341074	CCL3/HAVCR2/LRRK2/TLR4/HSPD1/TLR6/TREM2/HAMP	8
GO:0044788	modulation by host of viral process	8/2053	30/18722	0.0132398133338935	0.0531724560341074	NUCKS1/PPIB/IFI27/PSMC3/HSPA8/PHB/EIF2AK4/CFL1	8
GO:0061384	heart trabecula morphogenesis	8/2053	30/18722	0.0132398133338935	0.0531724560341074	BMP7/ENG/NOTCH1/ADAMTS1/FHL2/FKBP1A/TGFBR3/ADGRG6	8
GO:0002902	regulation of B cell apoptotic process	6/2053	19/18722	0.0132753898565155	0.0531724560341074	CD74/LYN/BTK/BCL6/SLC39A10/AURKB	6
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	6/2053	19/18722	0.0132753898565155	0.0531724560341074	PLK3/TRIAP1/SOX4/GTSE1/CDKN1A/PLK2	6
GO:0008356	asymmetric cell division	6/2053	19/18722	0.0132753898565155	0.0531724560341074	ASPM/ACTR2/PARD3/ACTR3/ARHGEF2/ING2	6
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	6/2053	19/18722	0.0132753898565155	0.0531724560341074	PAICS/GMPS/ADK/IMPDH2/AMPD3/PPAT	6
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	6/2053	19/18722	0.0132753898565155	0.0531724560341074	TYMP/DUT/UPP1/DPYD/UNG/DCTPP1	6
GO:0032616	interleukin-13 production	6/2053	19/18722	0.0132753898565155	0.0531724560341074	LGALS9/HLA-E/RARA/LILRA5/GATA3/IL18	6
GO:0032656	regulation of interleukin-13 production	6/2053	19/18722	0.0132753898565155	0.0531724560341074	LGALS9/HLA-E/RARA/LILRA5/GATA3/IL18	6
GO:0033194	response to hydroperoxide	6/2053	19/18722	0.0132753898565155	0.0531724560341074	AIF1/GPX1/JAK2/CD36/TRPM2/MGST1	6
GO:0044827	modulation by host of viral genome replication	6/2053	19/18722	0.0132753898565155	0.0531724560341074	NUCKS1/PPIB/IFI27/HSPA8/PHB/EIF2AK4	6
GO:0090670	RNA localization to Cajal body	6/2053	19/18722	0.0132753898565155	0.0531724560341074	NHP2/TCP1/CCT6A/CCT2/CCT4/CCT8	6
GO:0090671	telomerase RNA localization to Cajal body	6/2053	19/18722	0.0132753898565155	0.0531724560341074	NHP2/TCP1/CCT6A/CCT2/CCT4/CCT8	6
GO:0090672	telomerase RNA localization	6/2053	19/18722	0.0132753898565155	0.0531724560341074	NHP2/TCP1/CCT6A/CCT2/CCT4/CCT8	6
GO:0090685	RNA localization to nucleus	6/2053	19/18722	0.0132753898565155	0.0531724560341074	NHP2/TCP1/CCT6A/CCT2/CCT4/CCT8	6
GO:1903975	regulation of glial cell migration	6/2053	19/18722	0.0132753898565155	0.0531724560341074	CCL3/CCR2/TREM2/GPR183/IDH2/CX3CR1	6
GO:1903978	regulation of microglial cell activation	6/2053	19/18722	0.0132753898565155	0.0531724560341074	PTPRC/CCL3/LRRK2/GRN/TREM2/SPHK1	6
GO:0010822	positive regulation of mitochondrion organization	15/2053	74/18722	0.0133494465932577	0.0531984264841674	TNFSF10/PYCARD/PLAUR/SLC25A5/TREM2/PMAIP1/SLC25A4/PDCD5/VDAC1/CHCHD10/FIS1/PARK7/BAD/NMT1/BNIP3	15
GO:0006163	purine nucleotide metabolic process	58/2053	396/18722	0.013420407893925	0.0531984264841674	TMSB4X/TGFB1/SAMHD1/GIMAP7/LRRK2/HINT1/FBP1/PARP1/APP/KYNU/SLC26A2/RAN/MPC2/ACSS1/TECR/TREM2/HK3/PDK4/PAICS/P2RX7/PDE4A/HK2/DDIT4/PPT1/SLC2A6/SULT1A1/NUDT8/ALDOA/SLC25A1/LDHA/RHOA/STAT3/NUDT15/PNP/ARL2/ACSL4/GMPS/DHTKD1/TPST2/PMVK/PDHA1/STOML2/NME4/ADK/NUDT4/IMPDH2/RHOQ/DLG1/BAD/MPP1/AMPD3/INSR/VCP/NME1/DNPH1/PPAT/GAPDH/PRKAG2	58
GO:0001771	immunological synapse formation	5/2053	14/18722	0.0135109524271455	0.0531984264841674	MSN/HAVCR2/DOCK2/LGALS3/DLG1	5
GO:0002467	germinal center formation	5/2053	14/18722	0.0135109524271455	0.0531984264841674	TNFSF13B/MEF2C/TNFAIP3/BCL6/PKN1	5
GO:0002475	antigen processing and presentation via MHC class Ib	5/2053	14/18722	0.0135109524271455	0.0531984264841674	HLA-F/B2M/HLA-E/TAP2/CD1D	5
GO:0006287	base-excision repair, gap-filling	5/2053	14/18722	0.0135109524271455	0.0531984264841674	PCNA/FEN1/LIG1/PNKP/APEX1	5
GO:0009071	serine family amino acid catabolic process	5/2053	14/18722	0.0135109524271455	0.0531984264841674	SDS/GCSH/GLDC/CDO1/SHMT1	5
GO:0009159	deoxyribonucleoside monophosphate catabolic process	5/2053	14/18722	0.0135109524271455	0.0531984264841674	TYMP/UPP1/DPYD/PNP/DNPH1	5
GO:0034111	negative regulation of homotypic cell-cell adhesion	5/2053	14/18722	0.0135109524271455	0.0531984264841674	CD9/SH2B3/RDX/C1QTNF1/UBASH3B	5
GO:0035563	positive regulation of chromatin binding	5/2053	14/18722	0.0135109524271455	0.0531984264841674	GMNN/PARP9/CDT1/DTX3L/MBD2	5
GO:0043374	CD8-positive, alpha-beta T cell differentiation	5/2053	14/18722	0.0135109524271455	0.0531984264841674	NCKAP1L/LILRB4/RUNX1/IRF1/RUNX3	5
GO:0043922	negative regulation by host of viral transcription	5/2053	14/18722	0.0135109524271455	0.0531984264841674	CCL3/CCL4/NUCKS1/PSMC3/JUN	5
GO:0045579	positive regulation of B cell differentiation	5/2053	14/18722	0.0135109524271455	0.0531984264841674	NCKAP1L/BTK/SYK/INPP5D/BAD	5
GO:0045837	negative regulation of membrane potential	5/2053	14/18722	0.0135109524271455	0.0531984264841674	BNIP3L/PMAIP1/HEBP2/BNIP3/PTN	5
GO:0046131	pyrimidine ribonucleoside metabolic process	5/2053	14/18722	0.0135109524271455	0.0531984264841674	APOBEC3A/UPP1/CDA/APOBEC3G/APOBEC3C	5
GO:0046133	pyrimidine ribonucleoside catabolic process	5/2053	14/18722	0.0135109524271455	0.0531984264841674	APOBEC3A/UPP1/CDA/APOBEC3G/APOBEC3C	5
GO:0048875	chemical homeostasis within a tissue	5/2053	14/18722	0.0135109524271455	0.0531984264841674	VEGFA/CTSH/OAS1/EPAS1/HOMER1	5
GO:0051764	actin crosslink formation	5/2053	14/18722	0.0135109524271455	0.0531984264841674	AIF1/MARCKS/LCP1/FLNA/EPS8	5
GO:0060576	intestinal epithelial cell development	5/2053	14/18722	0.0135109524271455	0.0531984264841674	TYMS/IL6ST/YAP1/KLF5/CDKN1A	5
GO:0071481	cellular response to X-ray	5/2053	14/18722	0.0135109524271455	0.0531984264841674	NUCKS1/HAMP/GATA3/XRCC5/XRCC6	5
GO:0072160	nephron tubule epithelial cell differentiation	5/2053	14/18722	0.0135109524271455	0.0531984264841674	MEF2C/STAT1/CD24/GATA3/YAP1	5
GO:0090715	immunological memory formation process	5/2053	14/18722	0.0135109524271455	0.0531984264841674	HLA-DRA/HLA-DRB1/FGL2/CD46/BCL6	5
GO:1905049	negative regulation of metallopeptidase activity	5/2053	14/18722	0.0135109524271455	0.0531984264841674	TIMP1/SORL1/TIMP2/TIMP3/PICALM	5
GO:1990173	protein localization to nucleoplasm	5/2053	14/18722	0.0135109524271455	0.0531984264841674	TCP1/CCT6A/CCT2/CCT4/CCT8	5
GO:0032691	negative regulation of interleukin-1 beta production	10/2053	42/18722	0.0135301331358066	0.0531984264841674	LILRB4/TNFAIP3/GSTP1/ARRB2/NLRP3/CARD16/TREM2/CD33/CX3CR1/ACP5	10
GO:0032965	regulation of collagen biosynthetic process	10/2053	42/18722	0.0135301331358066	0.0531984264841674	VIM/TGFB1/ARRB2/RUNX1/CIITA/ENG/HDAC2/RGCC/RAP1A/SUCO	10
GO:0033574	response to testosterone	10/2053	42/18722	0.0135301331358066	0.0531984264841674	TSPO/MSN/NASP/DUSP1/SPP1/CALR/MTAP/CDK4/BAD/NME1	10
GO:0090317	negative regulation of intracellular protein transport	10/2053	42/18722	0.0135301331358066	0.0531984264841674	LRRK2/LMAN1/CD36/FERMT1/CHP1/BARD1/TXN/SVIP/SP100/PARK7	10
GO:1901293	nucleoside phosphate biosynthetic process	40/2053	256/18722	0.0135566831669623	0.0532679102827597	TMSB4X/TGFB1/DUT/UPP1/TYMS/PARP1/RRM1/NAMPT/KYNU/SLC26A2/MPC2/ACSS1/TECR/QPRT/PARP9/TREM2/PDK4/PAICS/DTYMK/RRM2/TK1/IDH2/PPT1/ALDOA/SLC25A1/UMPS/STAT3/PNP/ACSL4/GMPS/PDHA1/STOML2/NME4/ADK/IMPDH2/AMPD3/VCP/NME1/PPAT/PRKAG2	40
GO:0002691	regulation of cellular extravasation	9/2053	36/18722	0.0136196157510328	0.0534006477503184	ITGA4/PTAFR/CCR2/PTGER4/IL27RA/ADAM8/ICAM1/JAM3/MDK	9
GO:0017004	cytochrome complex assembly	9/2053	36/18722	0.0136196157510328	0.0534006477503184	CYBA/SCO2/COX20/UQCC2/COA4/SCO1/TTC19/UQCRFS1/COX17	9
GO:0090313	regulation of protein targeting to membrane	9/2053	36/18722	0.0136196157510328	0.0534006477503184	ITGB2/ITGAM/TCAF1/HRAS/CHP1/CIB1/MYO1C/ANK3/FIS1	9
GO:0043030	regulation of macrophage activation	13/2053	61/18722	0.013634965392248	0.0534006477503184	PTPRC/CD74/CCL3/CD84/HAVCR2/LRRK2/TLR4/HSPD1/GRN/TLR6/TREM2/HAMP/SPHK1	13
GO:1904356	regulation of telomere maintenance via telomere lengthening	13/2053	61/18722	0.013634965392248	0.0534006477503184	PARP1/PKIB/HNRNPA1/TCP1/CCT6A/CCT2/XRCC5/PNKP/HNRNPA2B1/CCT4/AURKB/CCT8/MAP3K4	13
GO:0007266	Rho protein signal transduction	24/2053	137/18722	0.0137704307929825	0.0538608766348728	ARHGDIB/WAS/GPR65/STMN1/LPAR6/HACD3/ADGRG1/CTNNAL1/MET/ITGB1/BCL6/ARHGAP4/KANK1/NRP1/RHOA/NET1/RHOG/EPS8/ARHGEF2/EPS8L2/RHOB/CFL1/CCDC125/RTKN	24
GO:0050684	regulation of mRNA processing	24/2053	137/18722	0.0137704307929825	0.0538608766348728	CELF2/SRSF2/MBNL3/ZFP36L1/NPM1/HNRNPA1/HSPA8/C1QBP/BARD1/SF1/PRDX6/RBM39/MAGOH/SRSF10/SRPK1/NCL/MBNL1/SRSF7/RBMX/TRA2B/SNRNP70/TIA1/PRPF19/SRSF4	24
GO:0051817	modulation of process of other organism involved in symbiotic interaction	16/2053	81/18722	0.0138053339271227	0.0539270856528231	CCL3/CCL4/CD4/DAG1/NUCKS1/PPIB/IFI27/PHB2/PSMC3/CX3CR1/HSPA8/PHB/EIF2AK4/JUN/INSR/CFL1	16
GO:1903533	regulation of protein targeting	16/2053	81/18722	0.0138053339271227	0.0539270856528231	ITGB2/RAC2/LRRK2/ITGAM/TCAF1/LMAN1/BNIP3L/HRAS/CHP1/CIB1/PDCD5/MYO1C/ANK3/SAE1/FIS1/HUWE1	16
GO:0032868	response to insulin	41/2053	264/18722	0.0138407392090764	0.0540302116164334	TNFSF10/LYN/SORL1/TLR2/UCP2/RETN/GGH/PARP1/IL1B/GSTP1/STAT1/SLC2A1/SOCS3/PRKDC/NUCKS1/ZFP36L1/ATP2B1/KCNQ1/PDK4/ICAM1/PRKCB/KANK1/GNAI2/CCND3/SMARCC1/HADH/CDK4/MYO1C/GRB2/VPS13C/FOXO4/RHOQ/SLC9A1/BCAR1/IGF1R/GAB1/INSR/MYO5A/PPAT/SRSF4/PPARG	41
GO:0007098	centrosome cycle	23/2053	130/18722	0.0139910857771447	0.0545107238070571	RANBP1/CDK1/NPM1/BRCA1/CHEK1/CEP152/ARL2/ATF5/SLC16A1/BRCA2/HAUS8/NDC80/HAUS1/PARD6B/CDK2/CENPJ/SASS6/CHMP4C/PLK2/CCP110/SAC3D1/KIF11/XRCC2	23
GO:0043467	regulation of generation of precursor metabolites and energy	23/2053	130/18722	0.0139910857771447	0.0545107238070571	HMGB1/FBP1/PHLDA2/APP/CDK1/P2RX7/DDIT4/PHB2/SLC2A6/UQCC2/CISD1/RHOA/STAT3/ARL2/COX7A2/CHCHD2/PARK7/BNIP3/INSR/VCP/TRAP1/PRKAG2/COX17	23
GO:0051028	mRNA transport	23/2053	130/18722	0.0139910857771447	0.0545107238070571	ZFP36/MX2/SLBP/HHEX/ZFP36L1/HNRNPA3/HNRNPA1/NUP214/IGF2BP3/UPF3A/MAGOHB/MYO1C/MAGOH/KHSRP/TPR/NCBP3/RANBP17/HNRNPA2B1/SRSF7/MVP/PABPN1/LRPPRC/NUP54	23
GO:0042742	defense response to bacterium	52/2053	350/18722	0.0143019739397215	0.0556648093200964	FCER1G/HLA-A/LYZ/S100A8/SLC11A1/CYBA/ISG15/PYCARD/C5AR1/GBP4/GBP2/HLA-E/HAVCR2/PLAC8/OAS2/TLR2/S100A12/CFP/FGR/CD4/TNFRSF14/CASP1/TNF/TLR4/TREM1/HMGB2/COLEC12/CD36/MPEG1/CEBPB/IRF8/GRN/RNASE6/TLR6/SYK/IL27RA/LYST/S100A9/TREM2/IL6R/HAMP/SPN/NAIP/OAS1/STAB1/RPS19/NLRP1/NOTCH2/MYD88/ACP5/ANXA3/DEFB1	52
GO:0043200	response to amino acid	21/2053	116/18722	0.0143058559952648	0.0556648093200964	CYBB/CYBA/LYN/PCNA/TNF/GSTP1/CEBPB/DNMT1/ICAM1/CDO1/RHOA/LAMTOR4/HNRNPD/GCLM/ASS1/COL4A1/BAD/IPO5/SLC38A9/PTN/ALAD	21
GO:0031056	regulation of histone modification	26/2053	152/18722	0.0143563829918721	0.0558252093008637	SPI1/LRRK2/VEGFA/IL1B/DNMT1/BCL6/RTF1/BRCA1/SET/CAMK2D/CHEK1/JDP2/ISL1/BRD7/GATA3/BRD4/EID1/PARK7/KMT2E/ING2/RIF1/ZNF451/LMNA/RPS6KA5/UBE2N/NCAPG2	26
GO:0005996	monosaccharide metabolic process	40/2053	257/18722	0.0144061210000199	0.0559823354923054	SLC2A3/HMGB1/FBP1/PHLDA2/TNF/SDS/PGP/SLC2A1/SERP1/HK3/KCNQ1/PDK4/OAS1/HK2/SLC35B4/PMAIP1/AKR1B1/ALDOA/DCXR/DDB1/SLC25A1/UXS1/FUCA1/FABP5/CHST15/LRP5/RPIA/FUOM/FUT8/PDHA1/NUDT5/BAD/GAA/MIDN/C1QTNF1/LCMT1/ATF3/INSR/MAPK14/GAPDH	40
GO:0003229	ventricular cardiac muscle tissue development	12/2053	55/18722	0.014515934059324	0.0562633103074574	TGFB1/LRP2/DSP/ENG/NOTCH1/DSG2/ISL1/FKBP1A/ID2/FOXC1/TGFBR3/TBX3	12
GO:0045620	negative regulation of lymphocyte differentiation	12/2053	55/18722	0.014515934059324	0.0562633103074574	FGL2/CD74/LILRB4/HMGB1/PRDX2/RUNX1/BCL6/IRF1/RUNX3/GLI3/ID2/MDK	12
GO:0098900	regulation of action potential	12/2053	55/18722	0.014515934059324	0.0562633103074574	FLNA/CD36/DSP/KCNAB2/DSG2/CAMK2D/KCNE3/GJA5/DSC2/SLC9A1/DLG1/AKAP9	12
GO:1905517	macrophage migration	12/2053	55/18722	0.014515934059324	0.0562633103074574	CCL3/CSF1R/C5AR1/CD9/C3AR1/CCR2/LGALS3/TREM2/PTK2B/CX3CR1/MDK/PTK2	12
GO:1903311	regulation of mRNA metabolic process	44/2053	288/18722	0.0145788596539118	0.0564707281623439	VIM/SLC11A1/ZFP36/ZFP36L2/CELF2/FUS/CARHSP1/PABPC1/SRSF2/MBNL3/ZFP36L1/NPM1/HNRNPR/HNRNPA1/SERBP1/BTG2/EXOSC8/HSPA8/C1QBP/BARD1/SF1/HNRNPD/PRDX6/RBM39/MYD88/MAGOH/KHSRP/SRSF10/HNRNPA0/SRPK1/NCL/APEX1/MBNL1/SRSF7/RBMX/AGO2/TRA2B/SNRNP70/TIA1/PRPF19/E2F1/YBX1/MAPK14/SRSF4	44
GO:0055076	transition metal ion homeostasis	24/2053	138/18722	0.0149882423687036	0.0580190027175623	S100A8/SLC11A1/B2M/FTH1/FTL/APP/HMOX1/SLC40A1/SLC25A37/SCO2/SOD1/MT1X/S100A9/HAMP/SLC39A10/EPAS1/MT2A/ANKRD9/SLC39A7/COMMD1/EIF2AK1/SCO1/TFRC/PICALM	24
GO:0061333	renal tubule morphogenesis	15/2053	75/18722	0.0150437008406101	0.0581961347799232	MEF2C/VEGFA/MAGED1/LAMA5/LGR5/TACSTD2/AHI1/GATA3/PBX1/COL4A1/LGR4/DLG1/GLI3/IRX2/GPC3	15
GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	23/2053	131/18722	0.0152624299992516	0.0587409496374457	ZEB2/TGFB1/PEG10/SKIL/FBN2/FBN1/HSP90AB1/NREP/ENG/HSPA5/LDLRAD4/CDKN1C/FERMT1/LTBP1/FOLR1/SDCBP/HSPA1A/FKBP1A/ING2/ZNF451/TGFBR3/EID2/PPARG	23
GO:0031579	membrane raft organization	7/2053	25/18722	0.0153048086645037	0.0587409496374457	PTPRC/MYADM/DOCK2/EMP2/PPT1/S100A10/DLG1	7
GO:0033622	integrin activation	7/2053	25/18722	0.0153048086645037	0.0587409496374457	PLEK/FERMT3/FN1/PTGER4/FERMT1/JAM3/FERMT2	7
GO:0035902	response to immobilization stress	7/2053	25/18722	0.0153048086645037	0.0587409496374457	SLC8A1/FOS/SOD2/PTK2B/ACTR2/FOXO4/ERCC1	7
GO:1901798	positive regulation of signal transduction by p53 class mediator	7/2053	25/18722	0.0153048086645037	0.0587409496374457	RPS7/RPL37/RPL23/UBB/PMAIP1/EEF1E1/RPS20	7
GO:0009066	aspartate family amino acid metabolic process	11/2053	49/18722	0.0153118075388275	0.0587409496374457	SDS/SDSL/ADI1/SMS/MTAP/ASS1/NIT2/PLOD2/ASNSD1/MTR/ENOPH1	11
GO:0010823	negative regulation of mitochondrion organization	11/2053	49/18722	0.0153118075388275	0.0587409496374457	TSPO/GPX1/ARRB2/SLC25A5/TRIAP1/HSPA1A/BNIP3/TFRC/LMNA/HUWE1/PPARG	11
GO:0014075	response to amine	11/2053	49/18722	0.0153118075388275	0.0587409496374457	NR4A2/RGS10/SOD1/CDK1/NR4A1/ICAM1/GLDC/HDAC2/ASS1/RGS2/NME1	11
GO:0032692	negative regulation of interleukin-1 production	11/2053	49/18722	0.0153118075388275	0.0587409496374457	LILRB4/TNFAIP3/GSTP1/ARRB2/NLRP3/CARD16/TREM2/CD33/CX3CR1/NLRP12/ACP5	11
GO:0050832	defense response to fungus	11/2053	49/18722	0.0153118075388275	0.0587409496374457	S100A8/SPI1/CLEC7A/COTL1/S100A12/CLEC4E/S100A9/HAMP/CX3CR1/USP15/GAPDH	11
GO:0060964	regulation of gene silencing by miRNA	11/2053	49/18722	0.0153118075388275	0.0587409496374457	ZFP36/TGFB1/EGFR/NEAT1/TNF/LIN28B/STAT3/NCOR2/AGO2/EIF4G1/PPARG	11
GO:0070741	response to interleukin-6	11/2053	49/18722	0.0153118075388275	0.0587409496374457	SPI1/JAK2/JAK1/SELPLG/IL6R/HAMP/ICAM1/STAT3/IL6ST/YAP1/PHB	11
GO:1904894	positive regulation of receptor signaling pathway via STAT	11/2053	49/18722	0.0153118075388275	0.0587409496374457	TGFB1/IL10RA/CD300A/JAK2/TNF/NOTCH1/IL6R/PTK2B/AKR1B1/CSH1/CENPJ	11
GO:0050000	chromosome localization	16/2053	82/18722	0.0154571034441476	0.0592604604887449	CENPF/CDT1/KPNB1/ACTR2/CDCA5/NUF2/KIF22/ACTR3/NDC80/EML4/NUDC/AURKB/CHMP4C/LMNA/CDCA8/KIFC1	16
GO:0032835	glomerulus development	13/2053	62/18722	0.0155694202322864	0.0596529510815571	PECAM1/MEF2C/CD24/BMP7/NOTCH1/IL6R/ENPEP/SULF2/NOTCH2/LGR4/FOXC1/BASP1/ASXL1	13
GO:0009199	ribonucleoside triphosphate metabolic process	17/2053	89/18722	0.0157175287669835	0.0601819863445443	TMSB4X/TGFB1/GIMAP7/LRRK2/PARP1/RAN/TREM2/ALDOA/RHOA/STAT3/STOML2/NME4/IMPDH2/RHOQ/VCP/NME1/PRKAG2	17
GO:0043648	dicarboxylic acid metabolic process	18/2053	96/18722	0.0158506059320784	0.0606528288217284	KYNU/GLUL/QPRT/DHFR/IDH2/GRHPR/OAT/FOLR1/FH/GCLM/SLC19A1/ASS1/MDH1/IDH1/MRPS36/NIT2/SHMT1/SDHA	18
GO:0061383	trabecula morphogenesis	10/2053	43/18722	0.0159436530486937	0.0609311581478741	FBN2/BMP7/ENG/NOTCH1/ADAMTS1/RHOA/FHL2/FKBP1A/TGFBR3/ADGRG6	10
GO:0098927	vesicle-mediated transport between endosomal compartments	10/2053	43/18722	0.0159436530486937	0.0609311581478741	CORO1A/MSN/FLNA/SORL1/EMP2/RDX/HOOK2/EZR/AKTIP/EEA1	10
GO:0060055	angiogenesis involved in wound healing	8/2053	31/18722	0.0161714777900004	0.0617624867854884	CXCR4/GPX1/VEGFA/ALOX5/TNF/TNFAIP3/DAG1/HPSE	8
GO:0048762	mesenchymal cell differentiation	37/2053	236/18722	0.0162248838256836	0.0619257916690512	S100A4/TGFB1/FLNA/MEF2C/FN1/HNRNPAB/IL1B/STAT1/GLIPR2/NRP2/DAG1/BMP7/LAMA5/ENG/SEMA4A/NOTCH1/LDLRAD4/SEMA6A/EZH2/NRP1/ISL1/HDAC2/RGCC/GATA3/DLG5/FOLR1/SDCBP/SEMA6D/TCOF1/EFNA1/FERMT2/CORO1C/FOXC1/TRIM28/MDK/TGFBR3/TBX3	37
GO:0045927	positive regulation of growth	40/2053	259/18722	0.0162348783825696	0.0619257916690512	S100A8/CXCR4/CYBA/MEF2C/FN1/EGFR/VEGFA/CXCL16/SASH3/PRKDC/CDK1/SERP1/S100A9/NOTCH1/PPIB/PTK2B/HAMP/TRPV2/HBEGF/ITSN2/NRP1/SPHK1/RHOA/CIB1/RPS6KA1/GOLGA4/TWF2/SDCBP/YAP1/PARP2/SLC9A1/CSH1/EZR/TFCP2L1/INSR/TGFBR3/BASP1/DNPH1/EIF4G1/MAPK14	40
GO:0045598	regulation of fat cell differentiation	24/2053	139/18722	0.0162900635462367	0.0620227861514377	ZFP36/TGFB1/ZFP36L2/ALOX5/TNF/ADIRF/METRNL/CEBPB/BMP7/ZFP36L1/JDP2/GATA3/LRP5/YAP1/KLF5/ANKRD26/FERMT2/CDS1/ID2/STK4/E2F1/MAPK14/ASXL1/PPARG	24
GO:0006862	nucleotide transport	9/2053	37/18722	0.0162913184957776	0.0620227861514377	SLC25A5/LRRC8C/SLC29A1/GJA1/SLC25A36/SLC25A4/SLC19A1/SLC25A17/SLC25A6	9
GO:0060416	response to growth hormone	9/2053	37/18722	0.0162913184957776	0.0620227861514377	LYN/JAK2/STAT6/STAT5A/STAT3/CACYBP/ASS1/CSH1/PTK2	9
GO:0010518	positive regulation of phospholipase activity	12/2053	56/18722	0.0166835877694651	0.063395520339956	C5AR1/CD86/EGFR/PTAFR/S1PR4/PLCB2/GNA15/PHB2/FLT1/HRAS/PHB/ARL1	12
GO:0031122	cytoplasmic microtubule organization	12/2053	56/18722	0.0166835877694651	0.063395520339956	PLK3/CCDC88A/CLIP1/CHP1/KPNB1/RHOA/CIB1/CCDC88B/HOOK2/EZR/DLG1/CENPJ	12
GO:0051653	spindle localization	12/2053	56/18722	0.0166835877694651	0.063395520339956	ITGB1/NUSAP1/MAD2L1/ASPM/GJA1/KPNB1/ACTR2/ACTR3/NDC80/GPSM2/CFL1/DYNLT1	12
GO:0043270	positive regulation of ion transport	42/2053	275/18722	0.0167798909466778	0.0637211048608016	CTSS/TSPO/TMSB4X/CCL3/CCL4/FLNA/TCAF1/CCR1/IL1B/PTAFR/CEBPB/CCR2/ARRB2/CXCL10/LILRA2/GLRX/IFNGR2/LILRA5/ITGB1/LGALS3/ATP2B1/TREM2/KCNQ1/TRPV2/P2RX7/VMP1/KCNMB1/KCNE3/CHP1/SLC6A4/CALM2/SNX4/ANK3/KCNN4/SLC9A1/DLG1/DMD/PTGES/AKAP9/HOMER1/ACTN4/COX17	42
GO:0016052	carbohydrate catabolic process	26/2053	154/18722	0.0168121114264792	0.0638030794173784	HMGB1/FBP1/AOAH/APP/AGL/HK3/P2RX7/HK2/DDIT4/SLC2A6/ALDOA/LDHA/STAT3/ARL2/LRP5/DHTKD1/FUT8/NUDT5/BAD/GAA/INSR/GK/HEXB/ENOSF1/GAPDH/PRKAG2	26
GO:0014823	response to activity	15/2053	76/18722	0.0168991306329212	0.0640522955132833	CXCR4/CYBA/SOD2/METRNL/HSPD1/PRKDC/SCO2/CDK1/COL4A2/HADH/GCLM/FIS1/KDM6B/PTN/ALAD	15
GO:0086001	cardiac muscle cell action potential	15/2053	76/18722	0.0168991306329212	0.0640522955132833	FLNA/SLC8A1/DSP/KCNQ1/DSG2/GJA1/CAMK2D/KCNE3/GJA5/DSC2/ANK3/YWHAE/DLG1/DMD/AKAP9	15
GO:0009308	amine metabolic process	21/2053	118/18722	0.0171727633666818	0.0650483460859159	ITGB2/SLC7A7/ITGAM/OAZ1/NR4A2/KYNU/SAT1/IL4I1/ALDH7A1/COMT/PNKD/SULT1A1/AKR1B1/EPAS1/SMS/GATA3/SRM/PARK7/GCH1/SAT2/SLC44A1	21
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	6/2053	20/18722	0.0172417212955128	0.0650630992283502	TYMP/DUT/UPP1/TYMS/DPYD/UMPS	6
GO:0043555	regulation of translation in response to stress	6/2053	20/18722	0.0172417212955128	0.0650630992283502	NPM1/RPS6KA1/EIF2AK4/EIF2AK1/PPP1R15A/EIF4G1	6
GO:0046629	gamma-delta T cell activation	6/2053	20/18722	0.0172417212955128	0.0650630992283502	PTPRC/NCKAP1L/LILRB1/SYK/JAML/SOX4	6
GO:0048025	negative regulation of mRNA splicing, via spliceosome	6/2053	20/18722	0.0172417212955128	0.0650630992283502	NPM1/C1QBP/SRSF10/SRSF7/RBMX/SRSF4	6
GO:0060252	positive regulation of glial cell proliferation	6/2053	20/18722	0.0172417212955128	0.0650630992283502	TSPO/LYN/EGFR/TNF/IL1B/E2F1	6
GO:2000757	negative regulation of peptidyl-lysine acetylation	6/2053	20/18722	0.0172417212955128	0.0650630992283502	SPI1/BRCA1/HINT2/SET/HDAC2/ZNF451	6
GO:1903531	negative regulation of secretion by cell	25/2053	147/18722	0.0172553034850161	0.0650734260905699	HLA-F/TNFRSF1B/SPI1/LGALS9/NCKAP1L/CD84/LILRB1/CD300A/UCP2/IL1B/HMOX1/CCR2/NOTCH1/RSAD2/PNKD/RHBDF2/ERP29/IDH2/GJA1/GNAI2/KLF7/FRMD4A/HADH/RAP1A/MIDN	25
GO:0034644	cellular response to UV	17/2053	90/18722	0.0174581259344282	0.0655068751728742	TIMP1/CRIP1/PCNA/PARP1/CARD16/MME/NPM1/PBK/CHEK1/DDB1/TRIAP1/POLD3/EIF2AK4/ERCC1/CDKN1A/AURKB/PTN	17
GO:0002524	hypersensitivity	4/2053	10/18722	0.0175776781713879	0.0655068751728742	HLA-E/C3/BTK/GATA3	4
GO:0009113	purine nucleobase biosynthetic process	4/2053	10/18722	0.0175776781713879	0.0655068751728742	PAICS/GMPS/SHMT1/PPAT	4
GO:0010944	negative regulation of transcription by competitive promoter binding	4/2053	10/18722	0.0175776781713879	0.0655068751728742	HHEX/TFAP2A/PHB/BHLHE41	4
GO:0030953	astral microtubule organization	4/2053	10/18722	0.0175776781713879	0.0655068751728742	KPNB1/EZR/DLG1/CENPJ	4
GO:0032070	regulation of deoxyribonuclease activity	4/2053	10/18722	0.0175776781713879	0.0655068751728742	HMGB1/PCNA/RPS3/NPM1	4
GO:0033314	mitotic DNA replication checkpoint signaling	4/2053	10/18722	0.0175776781713879	0.0655068751728742	CLSPN/CDC6/NAE1/TOPBP1	4
GO:0036363	transforming growth factor beta activation	4/2053	10/18722	0.0175776781713879	0.0655068751728742	HSP90AB1/LTBP1/ITGAV/ITGB8	4
GO:0042989	sequestering of actin monomers	4/2053	10/18722	0.0175776781713879	0.0655068751728742	TMSB4X/TMSB10/TWF2/SCIN	4
GO:0043101	purine-containing compound salvage	4/2053	10/18722	0.0175776781713879	0.0655068751728742	MTAP/PNP/ADK/AMPD3	4
GO:0050861	positive regulation of B cell receptor signaling pathway	4/2053	10/18722	0.0175776781713879	0.0655068751728742	NFAM1/SLC39A10/CMTM3/PRKCB	4
GO:0051660	establishment of centrosome localization	4/2053	10/18722	0.0175776781713879	0.0655068751728742	MAD2L1/PARD3/EZR/DLG1	4
GO:0071803	positive regulation of podosome assembly	4/2053	10/18722	0.0175776781713879	0.0655068751728742	MSN/LCP1/TNF/RHOA	4
GO:0090647	modulation of age-related behavioral decline	4/2053	10/18722	0.0175776781713879	0.0655068751728742	B2M/APP/BAZ2B/PICALM	4
GO:0140059	dendrite arborization	4/2053	10/18722	0.0175776781713879	0.0655068751728742	PHACTR1/TPBG/NRP1/PTN	4
GO:1901524	regulation of mitophagy	4/2053	10/18722	0.0175776781713879	0.0655068751728742	SLC25A5/SLC25A4/VDAC1/VPS13C	4
GO:1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	4/2053	10/18722	0.0175776781713879	0.0655068751728742	LYN/SORL1/EFNA1/PICALM	4
GO:2000121	regulation of removal of superoxide radicals	4/2053	10/18722	0.0175776781713879	0.0655068751728742	CD36/BMP7/DHFR/GCH1	4
GO:2000510	positive regulation of dendritic cell chemotaxis	4/2053	10/18722	0.0175776781713879	0.0655068751728742	SPI1/LGALS9/CALR/C1QBP	4
GO:0098656	anion transmembrane transport	38/2053	245/18722	0.0176141980237056	0.0656022272763709	SLC16A3/TCAF1/LRP2/PTAFR/SLC26A2/MPC2/SLC25A5/ITGB1/SLC25A3/LRRC8C/GJA1/SLC35B4/SLC25A1/SLC13A4/SLC1A5/SLC16A12/SFXN3/SLC25A4/SLC16A1/FOLR1/SLC19A1/SFXN1/SLC20A1/VDAC1/GOPC/RGS2/SLC9A1/SLC13A3/GABRE/BEST1/VDAC3/PCYOX1/SLC38A9/SLC25A17/MPC1/SLC25A6/SLC3A2/SLC1A3	38
GO:0006220	pyrimidine nucleotide metabolic process	11/2053	50/18722	0.0177404373298691	0.066031404453607	TYMP/DUT/UPP1/TYMS/DPYD/UNG/DTYMK/UMPS/NME4/DCTPP1/NME1	11
GO:0051302	regulation of cell division	29/2053	177/18722	0.0178245579130822	0.0663033772340317	TXNIP/EVI2B/TGFB1/VEGFA/IL1B/ORC6/PLK3/PRC1/CDC6/ASPM/RHOA/CALM2/CIB1/KIF23/BLM/BRCA2/KIF20B/RBL1/ECT2/CDK2AP2/AURKB/CHMP4C/MDK/PLK2/PTN/CCP110/PDGFA/YBX1/E2F7	29
GO:0051321	meiotic cell cycle	40/2053	261/18722	0.0182468952044693	0.0678323241801832	DUSP1/TOP2A/SMC2/RAD51AP1/SMC3/CALR/RAD51/CCNE1/ASPM/SMC4/UBB/RAD51C/MSH6/CKS2/ACTR2/PKMYT1/FBXO5/RAD21/CCNE2/NUF2/MND1/NCAPD3/BUB3/BRCA2/FANCD2/RAD50/PSMC3IP/ACTR3/RPA1/TTK/ERCC1/TOP2B/CDK2/ING2/RBBP8/EXO1/BUB1B/FIGNL1/FANCA/XRCC2	40
GO:0000722	telomere maintenance via recombination	5/2053	15/18722	0.0184693046829928	0.0682363473509587	RAD51/RAD51C/BRCA2/RAD50/ERCC1	5
GO:0006878	cellular copper ion homeostasis	5/2053	15/18722	0.0184693046829928	0.0682363473509587	APP/SCO2/MT2A/ANKRD9/SCO1	5
GO:0033599	regulation of mammary gland epithelial cell proliferation	5/2053	15/18722	0.0184693046829928	0.0682363473509587	GPX1/CCND1/PHB2/GATA3/BRCA2	5
GO:0045176	apical protein localization	5/2053	15/18722	0.0184693046829928	0.0682363473509587	ACTB/RDX/DLG5/JAM3/GOPC	5
GO:0045346	regulation of MHC class II biosynthetic process	5/2053	15/18722	0.0184693046829928	0.0682363473509587	SPI1/JAK2/TLR4/CIITA/HDAC2	5
GO:0060099	regulation of phagocytosis, engulfment	5/2053	15/18722	0.0184693046829928	0.0682363473509587	NCKAP1L/CD300A/CD36/C3/TREM2	5
GO:0060253	negative regulation of glial cell proliferation	5/2053	15/18722	0.0184693046829928	0.0682363473509587	TSPO/NOTCH1/IDH2/ASCL2/PTN	5
GO:1900029	positive regulation of ruffle assembly	5/2053	15/18722	0.0184693046829928	0.0682363473509587	HRAS/PFN1/EPS8/EPS8L2/COBL	5
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	5/2053	15/18722	0.0184693046829928	0.0682363473509587	ZFP36/ZFP36L2/PABPC1/ZFP36L1/AGO2	5
GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	5/2053	15/18722	0.0184693046829928	0.0682363473509587	TGFB1/TNF/LIN28B/STAT3/NCOR2	5
GO:0061564	axon development	66/2053	467/18722	0.018551904203433	0.068499338597291	TSPO/FLNA/S100A6/FN1/RAC2/SKIL/ACTB/KLF4/SPP1/JAK2/STMN1/VEGFA/PLXNC1/NR4A2/APP/ITGA4/GRN/VASP/NRP2/HSP90AA1/HSP90AB1/DAG1/BSG/C12orf57/BMP7/LAMA5/ITGB1/ALCAM/NREP/SEMA4A/NOTCH1/ARHGAP4/DHFR/TRPV2/SEMA6A/NRP1/KLF7/ISL1/NOTCH2/PARD3/GOLGA4/GATA3/EPHB4/TWF2/FOLR1/ANK3/JAM3/SEMA6D/EFNA1/PTPRF/AFG3L2/SIAH1/RHOG/VCL/PARD6B/TOP2B/PALLD/GLI3/NUMB/PICALM/PTN/PTK2/RPS6KA5/MTR/COBL/DYNLT1	66
GO:0009126	purine nucleoside monophosphate metabolic process	10/2053	44/18722	0.0186621929671362	0.0687795809599614	PAICS/PNP/GMPS/ADK/IMPDH2/DLG1/MPP1/AMPD3/DNPH1/PPAT	10
GO:0042269	regulation of natural killer cell mediated cytotoxicity	10/2053	44/18722	0.0186621929671362	0.0687795809599614	HLA-B/HLA-A/HLA-F/LGALS9/HLA-E/HAVCR2/LILRB1/ARRB2/CADM1/VAV1	10
GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	10/2053	44/18722	0.0186621929671362	0.0687795809599614	IL10RA/CD300A/JAK2/TNF/NOTCH1/IL6R/PTK2B/AKR1B1/CSH1/CENPJ	10
GO:0050657	nucleic acid transport	27/2053	163/18722	0.0190023140032003	0.0695878474994985	ZFP36/MX2/SLBP/RAN/HHEX/ZFP36L1/NPM1/HNRNPA3/HNRNPA1/NUP214/IGF2BP3/UPF3A/NXT1/MAGOHB/MYO1C/MAGOH/KHSRP/TPR/NCBP3/RANBP17/HNRNPA2B1/SRSF7/MVP/PABPN1/LRPPRC/NUP54/YBX1	27
GO:0050658	RNA transport	27/2053	163/18722	0.0190023140032003	0.0695878474994985	ZFP36/MX2/SLBP/RAN/HHEX/ZFP36L1/NPM1/HNRNPA3/HNRNPA1/NUP214/IGF2BP3/UPF3A/NXT1/MAGOHB/MYO1C/MAGOH/KHSRP/TPR/NCBP3/RANBP17/HNRNPA2B1/SRSF7/MVP/PABPN1/LRPPRC/NUP54/YBX1	27
GO:0002092	positive regulation of receptor internalization	7/2053	26/18722	0.0190090803419463	0.0695878474994985	VEGFA/ARRB2/SYK/AHI1/CD63/INSR/AP2M1	7
GO:0006760	folic acid-containing compound metabolic process	7/2053	26/18722	0.0190090803419463	0.0695878474994985	TYMS/GGH/DHFR/FOLR1/SLC19A1/GCH1/SHMT1	7
GO:0009164	nucleoside catabolic process	7/2053	26/18722	0.0190090803419463	0.0695878474994985	APOBEC3A/UPP1/DPYD/CDA/APOBEC3G/APOBEC3C/PNP	7
GO:0032515	negative regulation of phosphoprotein phosphatase activity	7/2053	26/18722	0.0190090803419463	0.0695878474994985	NCKAP1L/TNF/LGALS3/GNAI2/MASTL/FKBP1A/PPP1R15A	7
GO:0032682	negative regulation of chemokine production	7/2053	26/18722	0.0190090803419463	0.0695878474994985	LGALS9/LILRB4/KLF4/GSTP1/OAS1/SUZ12/SIRPA	7
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	7/2053	26/18722	0.0190090803419463	0.0695878474994985	PTPRC/RPS3/NFAM1/SLC39A10/CMTM3/PRKCB/KCNN4	7
GO:0060669	embryonic placenta morphogenesis	7/2053	26/18722	0.0190090803419463	0.0695878474994985	SPINT1/SPINT2/SOCS3/BMP7/ZFP36L1/GRB2/TRIM28	7
GO:0070102	interleukin-6-mediated signaling pathway	7/2053	26/18722	0.0190090803419463	0.0695878474994985	SPI1/JAK2/JAK1/IL6R/STAT3/IL6ST/YAP1	7
GO:1904353	regulation of telomere capping	7/2053	26/18722	0.0190090803419463	0.0695878474994985	PKIB/HNRNPD/RAD50/PNKP/ERCC1/AURKB/MAP3K4	7
GO:0009165	nucleotide biosynthetic process	39/2053	254/18722	0.0190252308813737	0.069604503224538	TMSB4X/TGFB1/DUT/UPP1/TYMS/PARP1/RRM1/NAMPT/KYNU/SLC26A2/MPC2/ACSS1/TECR/QPRT/PARP9/TREM2/PDK4/PAICS/DTYMK/RRM2/IDH2/PPT1/ALDOA/SLC25A1/UMPS/STAT3/PNP/ACSL4/GMPS/PDHA1/STOML2/NME4/ADK/IMPDH2/AMPD3/VCP/NME1/PPAT/PRKAG2	39
GO:0002011	morphogenesis of an epithelial sheet	12/2053	57/18722	0.0190861564375619	0.0696575052465763	CD44/FLNA/ITGA5/DAG1/BMP7/NOTCH1/HBEGF/FERMT1/CD151/RHOA/NOTCH2/FERMT2	12
GO:0010257	NADH dehydrogenase complex assembly	12/2053	57/18722	0.0190861564375619	0.0696575052465763	NDUFA10/NDUFB9/NDUFB4/NDUFB7/NDUFB11/NDUFA6/NDUFAB1/NDUFS8/NDUFC2/NDUFA13/NDUFB10/NDUFA8	12
GO:0010883	regulation of lipid storage	12/2053	57/18722	0.0190861564375619	0.0696575052465763	MSR1/TNF/CD36/C3/NFKBIA/MEST/TREM2/HILPDA/PLIN2/ITGAV/ASXL1/PPARG	12
GO:0032981	mitochondrial respiratory chain complex I assembly	12/2053	57/18722	0.0190861564375619	0.0696575052465763	NDUFA10/NDUFB9/NDUFB4/NDUFB7/NDUFB11/NDUFA6/NDUFAB1/NDUFS8/NDUFC2/NDUFA13/NDUFB10/NDUFA8	12
GO:0098586	cellular response to virus	16/2053	84/18722	0.0192154077352746	0.0700865935633117	LGALS9/POU2F2/OASL/IRF7/CXCL10/TLR7/HSP90AA1/IFI6/OAS1/PHB2/BIRC3/C1QBP/USP15/PHB/DDX58/MAPK14	16
GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	19/2053	105/18722	0.0192292338435505	0.0700944125524319	RAC2/P2RX7/CCDC88A/HRAS/NRP1/ACTR2/TWF2/ANLN/ACTR3/FNBP1L/WASF2/PFN1/EPS8/RHOQ/EPS8L2/ATMIN/DOCK11/CCP110/COBL	19
GO:0048713	regulation of oligodendrocyte differentiation	9/2053	38/18722	0.0193271536187069	0.0704085742029394	CXCR4/TNFRSF1B/TLR2/DAG1/NOTCH1/RHEB/HDAC2/MDK/PTN	9
GO:0007435	salivary gland morphogenesis	8/2053	32/18722	0.0195439009763535	0.0711118289012255	TGFB1/TNF/TGM2/DAG1/BMP7/LAMA5/NRP1/PDGFA	8
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	8/2053	32/18722	0.0195439009763535	0.0711118289012255	TNFAIP3/HHEX/NR2F2/CDKN1C/CDKN2A/CDKN1A/IPO5/IPO7	8
GO:0035051	cardiocyte differentiation	26/2053	156/18722	0.0195894102971539	0.071234219262378	TGFB1/SLC8A1/MEF2C/EGFR/VEGFA/ARRB2/MEF2A/RARA/CDK1/BMP7/ITGB1/NOTCH1/CALR/HAMP/ISL1/CACYBP/FOLR1/PARP2/OBSL1/RGS2/SLC9A1/FHL2/TGFBR3/KDM6B/LMNA/TBX3	26
GO:0042552	myelination	23/2053	134/18722	0.0196314665854658	0.0713439124850364	CXCR4/TYMP/TNFRSF1B/CD9/TLR2/MBP/DAG1/ITGAX/SOD1/RARA/ITGB4/DEGS1/PARD3/MAL2/JAM3/CMTM8/AFG3L2/DLG1/GPC1/PTN/HEXB/ADGRG6/NDRG1	23
GO:0006401	RNA catabolic process	42/2053	278/18722	0.019850306730644	0.0720955450265522	VIM/SLC11A1/TNFRSF1B/ZFP36/ZFP36L2/OAS2/ISG20/RNASE6/FEN1/FUS/CARHSP1/PABPC1/RNASET2/LIN28B/ZFP36L1/NPM1/HNRNPR/SERBP1/BTG2/EXOSC8/LSM2/RNASEH2A/LSM4/SLIRP/LSM5/HNRNPD/UPF3A/MAGOHB/LSM7/MYD88/MAGOH/KHSRP/SND1/HNRNPA0/APEX1/HSPA1A/AGO2/LRPPRC/E2F1/MRTO4/YBX1/MAPK14	42
GO:0030837	negative regulation of actin filament polymerization	13/2053	64/18722	0.020056546666011	0.0728005323630165	TMSB4X/CAPG/TMSB10/MYADM/KANK1/RDX/KANK4/TWF2/SCIN/SPTBN1/PFN1/EPS8/TRIOBP	13
GO:0051224	negative regulation of protein transport	22/2053	127/18722	0.0200713532529765	0.0728102294545702	UCP2/LRRK2/LMAN1/IL1B/CD36/CSK/RSAD2/RHBDF2/ERP29/IDH2/FERMT1/CHP1/BARD1/KLF7/FRMD4A/TXN/HADH/SVIP/GOPC/SP100/PARK7/MIDN	22
GO:0032964	collagen biosynthetic process	11/2053	51/18722	0.0204442259856788	0.0741180398272341	VIM/TGFB1/ARRB2/RUNX1/CIITA/ENG/SERPINH1/HDAC2/RGCC/RAP1A/SUCO	11
GO:0006304	DNA modification	21/2053	120/18722	0.020470707693192	0.0741692307724349	APOBEC3A/SPI1/FOS/HELLS/PARP1/DNMT1/UNG/BRCA1/EZH2/APOBEC3G/APOBEC3C/GATA3/PARP2/KDM1B/APEX1/MIS18A/KMT2E/ASCC3/TRIM28/MBD2/MBD3	21
GO:0009185	ribonucleoside diphosphate metabolic process	19/2053	106/18722	0.0210974244575375	0.0762900613283487	FBP1/APP/HK3/P2RX7/HK2/DDIT4/SLC2A6/ALDOA/LDHA/STAT3/ARL2/DHTKD1/NUDT5/DLG1/BAD/MPP1/INSR/GAPDH/PRKAG2	19
GO:0046620	regulation of organ growth	19/2053	106/18722	0.0210974244575375	0.0762900613283487	MEF2C/DUSP9/RUNX1/SASH3/SOD1/CDK1/SERP1/NOTCH1/HAMP/GJA1/SLC6A4/YAP1/PARP2/RGS2/STK4/FOXC1/TGFBR3/BASP1/MAPK14	19
GO:0001837	epithelial to mesenchymal transition	26/2053	157/18722	0.0211069169675098	0.0762900613283487	S100A4/TGFB1/FLNA/HNRNPAB/IL1B/GLIPR2/DAG1/BMP7/ENG/NOTCH1/LDLRAD4/EZH2/ISL1/HDAC2/RGCC/GATA3/DLG5/SDCBP/TCOF1/EFNA1/FERMT2/FOXC1/TRIM28/MDK/TGFBR3/TBX3	26
GO:1902600	proton transmembrane transport	26/2053	157/18722	0.0211069169675098	0.0762900613283487	TMSB4X/UCP2/HVCN1/COX6A1/CYB5A/SLC25A5/ATP6V1F/SLC25A3/PHB2/SLC15A3/ATP6V1C2/CHP1/SLC25A4/STOML2/SLC9A1/PARK7/ATP6V1B1/CYC1/UQCR10/TCIRG1/ATP6V1B2/COX5A/UQCRFS1/ATP6V0E1/ACTN4/COX17	26
GO:0061136	regulation of proteasomal protein catabolic process	30/2053	187/18722	0.0211912082990237	0.0765486151680567	GPX1/LRRK2/PLK3/HSP90AB1/TREM2/PSME2/PSMC3/UBB/PBK/TRIB1/PSMC1/NUDT15/SMARCC1/PSMD14/SDCBP/BAG2/USP14/SVIP/PITHD1/PSMC2/TMTC3/PARK7/COMMD1/RAD23B/HSPA1A/CDK2/VCP/PLK2/GABARAP/ALAD	30
GO:0006165	nucleoside diphosphate phosphorylation	18/2053	99/18722	0.0212926050233593	0.0768223873362331	FBP1/APP/HK3/DTYMK/P2RX7/HK2/DDIT4/SLC2A6/ALDOA/LDHA/STAT3/ARL2/DHTKD1/NME4/INSR/NME1/GAPDH/PRKAG2	18
GO:0010717	regulation of epithelial to mesenchymal transition	18/2053	99/18722	0.0212926050233593	0.0768223873362331	TGFB1/IL1B/GLIPR2/DAG1/BMP7/ENG/NOTCH1/LDLRAD4/EZH2/ISL1/HDAC2/RGCC/GATA3/SDCBP/EFNA1/FERMT2/FOXC1/MDK	18
GO:0001656	metanephros development	16/2053	85/18722	0.0213381695903745	0.0768943048301785	FBN1/STAT1/CTSH/BMP7/AKR1B1/FRAS1/GATA3/DLG5/LGR4/ID3/YAP1/GLI3/BASP1/PDGFA/IRX2/GPC3	16
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	16/2053	85/18722	0.0213381695903745	0.0768943048301785	CSF1R/LYN/JAK2/TNF/SOCS3/PARP9/IL6R/SH2B3/ISL1/SUZ12/HDAC2/IL6ST/HCLS1/CSH1/PARP14/IL18	16
GO:1903312	negative regulation of mRNA metabolic process	17/2053	92/18722	0.0213816003575264	0.0769775860312234	SLC11A1/ZFP36/FUS/PABPC1/NPM1/C1QBP/BARD1/HNRNPD/MYD88/SRSF10/HNRNPA0/SRSF7/RBMX/E2F1/YBX1/MAPK14/SRSF4	17
GO:0046879	hormone secretion	44/2053	295/18722	0.0213869393190082	0.0769775860312234	HLA-DRB1/LYN/EGFR/UCP2/SPP1/JAK2/RETN/ALOX5/TNF/IL1B/IL1RN/BTK/GLUL/MPC2/SERP1/DPP4/KCNQ1/GJA1/FAM3B/HMGN3/UQCC2/TRPM2/KLF7/ISL1/SYT7/SOX4/HADH/GATA3/SNX4/ACSL4/SLC16A1/LRP5/CYB5R4/CAMK2G/PARK7/PHPT1/BAD/TCIRG1/MIDN/C1QTNF1/ENSA/TBX3/TM7SF3/CCDC186	44
GO:0035987	endodermal cell differentiation	10/2053	45/18722	0.0217059696148421	0.0780061355884036	ITGB2/FN1/ITGA5/ITGA4/LAMB1/COL4A2/RTF1/ITGB5/ITGAV/MMP15	10
GO:0051180	vitamin transport	10/2053	45/18722	0.0217059696148421	0.0780061355884036	SLC2A3/LRP2/SLC2A1/TCN2/SLC2A6/FOLR1/SLC19A1/SLC52A1/SLC19A3/CD320	10
GO:0009161	ribonucleoside monophosphate metabolic process	12/2053	58/18722	0.0217377097839685	0.0780061355884036	UPP1/DPYD/PAICS/UMPS/PNP/GMPS/ADK/IMPDH2/DLG1/MPP1/AMPD3/PPAT	12
GO:0010043	response to zinc ion	12/2053	58/18722	0.0217377097839685	0.0780061355884036	S100A8/TSPO/CRIP1/SOD2/GGH/PARP1/HVCN1/MT1X/HAMP/MT2A/ASS1/ALAD	12
GO:0043525	positive regulation of neuron apoptotic process	12/2053	58/18722	0.0217377097839685	0.0780061355884036	TYROBP/CCL3/ITGAM/TNF/GRN/CTSZ/MCL1/TFAP2A/RHOA/MYBL2/FIS1/JUN	12
GO:0001952	regulation of cell-matrix adhesion	22/2053	128/18722	0.0218085021160669	0.0781891638676109	VEGFA/CD36/DAG1/BCL6/PTK2B/EMP2/RRAS/RASA1/S100A10/LIMS1/FERMT1/PLEKHA2/NRP1/RHOA/CIB1/CDK6/CDKN2A/FERMT2/SLC9A1/VCL/CORO1C/PTK2	22
GO:1901605	alpha-amino acid metabolic process	31/2053	195/18722	0.0218147767190634	0.0781891638676109	SLC7A7/SDS/GCSH/KYNU/GLUL/IL4I1/DHFR/COMT/DDAH2/GLDC/SDSL/ADI1/CDO1/SMS/MTAP/OAT/GCLM/GMPS/ASS1/PARK7/PYCR2/NIT2/QDPR/PLOD2/SHMT1/RIMKLB/ASNSD1/GFPT1/MTR/PPAT/ENOPH1	31
GO:0000002	mitochondrial genome maintenance	6/2053	21/18722	0.0219513245548077	0.078211370147771	TYMP/PARP1/MEF2A/SLC25A36/SLC25A4/MGME1	6
GO:0006244	pyrimidine nucleotide catabolic process	6/2053	21/18722	0.0219513245548077	0.078211370147771	TYMP/DUT/UPP1/DPYD/UNG/DCTPP1	6
GO:0006925	inflammatory cell apoptotic process	6/2053	21/18722	0.0219513245548077	0.078211370147771	MEF2C/CTSL/IRF7/PLEKHO2/TCP1/CDKN2A	6
GO:0009067	aspartate family amino acid biosynthetic process	6/2053	21/18722	0.0219513245548077	0.078211370147771	ADI1/MTAP/PLOD2/ASNSD1/MTR/ENOPH1	6
GO:0009127	purine nucleoside monophosphate biosynthetic process	6/2053	21/18722	0.0219513245548077	0.078211370147771	PAICS/GMPS/ADK/IMPDH2/AMPD3/PPAT	6
GO:0010988	regulation of low-density lipoprotein particle clearance	6/2053	21/18722	0.0219513245548077	0.078211370147771	CSK/TREM2/KHSRP/CNPY2/MYLIP/LDLRAP1	6
GO:0033630	positive regulation of cell adhesion mediated by integrin	6/2053	21/18722	0.0219513245548077	0.078211370147771	NCKAP1L/SYK/PTPN6/FERMT1/CIB1/RAC3	6
GO:0042454	ribonucleoside catabolic process	6/2053	21/18722	0.0219513245548077	0.078211370147771	APOBEC3A/UPP1/CDA/APOBEC3G/APOBEC3C/PNP	6
GO:1902307	positive regulation of sodium ion transmembrane transport	6/2053	21/18722	0.0219513245548077	0.078211370147771	GLRX/CHP1/ANK3/SLC9A1/DMD/ACTN4	6
GO:1903427	negative regulation of reactive oxygen species biosynthetic process	6/2053	21/18722	0.0219513245548077	0.078211370147771	PAGE4/HSPD1/RHOA/STAT3/PARK7/TRAP1	6
GO:0010721	negative regulation of cell development	29/2053	180/18722	0.0219769432573313	0.0782561777709127	TSPO/SORL1/B2M/LILRB1/FBLN1/SPP1/VEGFA/FBN1/TNF/IL1B/GBP1/BMP7/SEMA4A/NOTCH1/TREM2/ARHGAP4/SEMA6A/ID1/IDH2/KANK1/TACSTD2/ASCL2/NRP1/SEMA6D/CORO1C/PRTG/PTN/ACTN4/DYNLT1	29
GO:0001704	formation of primary germ layer	21/2053	121/18722	0.0222935232888837	0.0793363818109739	ITGB2/DUSP1/FN1/KLF4/ITGA5/ITGA4/WLS/DUSP2/LAMB1/BMP7/ITGB1/ITGB4/COL4A2/RTF1/GJA1/ITGB5/ITGAV/DUSP5/FOXC1/KDM6B/MMP15	21
GO:0001701	in utero embryonic development	53/2053	367/18722	0.0223320075356005	0.0794262271568482	NASP/SPINT1/SKIL/KLF4/SPINT2/JUNB/LPAR6/VEGFA/KLF2/PHLDA2/CEBPB/SOCS3/VASH1/SCO2/BMP7/ITGB1/NOTCH1/NR2F2/ZFP36L1/ASF1B/RRM2/RTF1/CMTM3/MFNG/SLC39A1/MSH2/CHEK1/KRT8/EPAS1/ASCL2/AMOT/NOTCH2/GATA3/GRB2/BRCA2/FUT8/YAP1/SBDS/MBNL1/COPS3/NMT1/GLI3/STK4/RBBP8/FOXC1/TRIM28/ACTL6A/TBX3/YBX1/MBD3/E2F7/XRCC2/NCAPG2	53
GO:0051310	metaphase plate congression	13/2053	65/18722	0.0226333237734151	0.0804025711311372	CENPF/CDT1/KPNB1/CDCA5/NUF2/KIF22/NDC80/EML4/NUDC/AURKB/CHMP4C/CDCA8/KIFC1	13
GO:1905330	regulation of morphogenesis of an epithelium	13/2053	65/18722	0.0226333237734151	0.0804025711311372	VEGFA/TNF/MAGED1/CXCL10/ITGAX/BMP7/PHB2/GJA1/TACSTD2/GATA3/LGR4/MDK/PDGFA	13
GO:0002244	hematopoietic progenitor cell differentiation	20/2053	114/18722	0.0227295634263692	0.0806966748865179	PTPRC/PLEK/CSF1R/SPI1/TGFB1/PRKDC/TOP2A/PTPN6/NOTCH1/FLT1/SOX4/GATA3/JAM3/DHTKD1/ESCO2/XRCC5/ZFAT/SBDS/FOXC1/HSPA9	20
GO:0086091	regulation of heart rate by cardiac conduction	9/2053	39/18722	0.0227518650740174	0.080728084236608	DSP/KCNQ1/DSG2/CAMK2D/KCNE3/ISL1/DSC2/YWHAE/AKAP9	9
GO:0000910	cytokinesis	28/2053	173/18722	0.0227780263976406	0.0807731432540447	STMN1/MYH10/PLK3/PRC1/NUSAP1/CDC6/RASA1/RHOA/ACTR2/CALM2/KIF23/CKAP2/ANK3/ANLN/BRCA2/KIF20B/SPTBN1/ACTR3/ECT2/TTC19/RHOB/AURKB/CHMP4C/PLK2/KIF4A/CCP110/RTKN/E2F7	28
GO:0007272	ensheathment of neurons	23/2053	136/18722	0.0230479296508606	0.0816337531907697	CXCR4/TYMP/TNFRSF1B/CD9/TLR2/MBP/DAG1/ITGAX/SOD1/RARA/ITGB4/DEGS1/PARD3/MAL2/JAM3/CMTM8/AFG3L2/DLG1/GPC1/PTN/HEXB/ADGRG6/NDRG1	23
GO:0008366	axon ensheathment	23/2053	136/18722	0.0230479296508606	0.0816337531907697	CXCR4/TYMP/TNFRSF1B/CD9/TLR2/MBP/DAG1/ITGAX/SOD1/RARA/ITGB4/DEGS1/PARD3/MAL2/JAM3/CMTM8/AFG3L2/DLG1/GPC1/PTN/HEXB/ADGRG6/NDRG1	23
GO:0032526	response to retinoic acid	19/2053	107/18722	0.0231018730359111	0.0817765417200392	LYN/DUSP1/KLF4/SERPINF1/CTSH/RARA/PTK2B/PHB2/GJA1/SLC6A4/SUZ12/HDAC2/TWF2/YAP1/PTGES/YES1/NDUFA13/ASXL1/SLC10A3	19
GO:0070227	lymphocyte apoptotic process	14/2053	72/18722	0.0232077887567617	0.0820339529076179	CD74/TSC22D3/LGALS9/LYN/BTK/LGALS3/BCL6/ADAM8/SLC39A10/RPS6/EFNA1/AURKB/GLI3/PKN1	14
GO:0002790	peptide secretion	37/2053	242/18722	0.0232398420869809	0.0820339529076179	S100A8/HLA-DRB1/CD74/EGFR/UCP2/JAK2/ALOX5/TNF/IL1B/IL1RN/GLUL/MPC2/SERP1/DPP4/GJA1/FAM3B/HMGN3/UQCC2/TRPM2/KLF7/ISL1/SYT7/SOX4/HADH/ACSL4/SLC16A1/LRP5/CYB5R4/CAMK2G/PARK7/PHPT1/BAD/TCIRG1/MIDN/ENSA/TM7SF3/CCDC186	37
GO:0000027	ribosomal large subunit assembly	7/2053	27/18722	0.0232976426257635	0.0820339529076179	RPLP0/RPL5/RPL23A/RPL3/MRPL20/BRIX1/MRTO4	7
GO:0009651	response to salt stress	7/2053	27/18722	0.0232976426257635	0.0820339529076179	TNF/HSP90AB1/ZFP36L1/AKR1B1/XRCC5/XRCC6/EFHD1	7
GO:0039529	RIG-I signaling pathway	7/2053	27/18722	0.0232976426257635	0.0820339529076179	OASL/PHB2/BIRC3/C1QBP/USP15/PHB/DDX58	7
GO:0048873	homeostasis of number of cells within a tissue	7/2053	27/18722	0.0232976426257635	0.0820339529076179	CORO1A/CCR2/SASH3/NOTCH1/FH/LIPA/RAC3	7
GO:0060142	regulation of syncytium formation by plasma membrane fusion	7/2053	27/18722	0.0232976426257635	0.0820339529076179	TYROBP/CD53/PLEKHO1/CXCL10/CAMK1/TREM2/MAPK14	7
GO:0098901	regulation of cardiac muscle cell action potential	7/2053	27/18722	0.0232976426257635	0.0820339529076179	DSP/DSG2/CAMK2D/GJA5/DSC2/DLG1/AKAP9	7
GO:1903203	regulation of oxidative stress-induced neuron death	7/2053	27/18722	0.0232976426257635	0.0820339529076179	TLR4/PARP1/TLR6/TREM2/MCL1/TRPM2/PARK7	7
GO:0009156	ribonucleoside monophosphate biosynthetic process	8/2053	33/18722	0.0233882829688181	0.0820785233505808	UPP1/PAICS/UMPS/GMPS/ADK/IMPDH2/AMPD3/PPAT	8
GO:0010984	regulation of lipoprotein particle clearance	8/2053	33/18722	0.0233882829688181	0.0820785233505808	LRPAP1/CSK/TREM2/APOC1/KHSRP/CNPY2/MYLIP/LDLRAP1	8
GO:1901976	regulation of cell cycle checkpoint	8/2053	33/18722	0.0233882829688181	0.0820785233505808	DUSP1/MAD2L1/CDT1/RPA2/WDR76/TPR/NDC80/LCMT1	8
GO:1903146	regulation of autophagy of mitochondrion	8/2053	33/18722	0.0233882829688181	0.0820785233505808	TSPO/SLC25A5/BNIP3L/SLC25A4/VDAC1/VPS13C/PARK7/BNIP3	8
GO:1904030	negative regulation of cyclin-dependent protein kinase activity	8/2053	33/18722	0.0233882829688181	0.0820785233505808	TNFAIP3/HHEX/NR2F2/CDKN1C/CDKN2A/CDKN1A/IPO5/IPO7	8
GO:0044728	DNA methylation or demethylation	18/2053	100/18722	0.0233923791549155	0.0820785233505808	APOBEC3A/SPI1/FOS/HELLS/PARP1/DNMT1/BRCA1/EZH2/APOBEC3G/APOBEC3C/GATA3/KDM1B/APEX1/MIS18A/KMT2E/TRIM28/MBD2/MBD3	18
GO:0043392	negative regulation of DNA binding	11/2053	52/18722	0.0234396452277671	0.0821482893496512	TMSB4X/JAK2/IFI16/HMOX1/NFKBIA/ID1/HDAC2/MSX2/SP100/JUN/E2F1	11
GO:0060147	regulation of posttranscriptional gene silencing	11/2053	52/18722	0.0234396452277671	0.0821482893496512	ZFP36/TGFB1/EGFR/NEAT1/TNF/LIN28B/STAT3/NCOR2/AGO2/EIF4G1/PPARG	11
GO:0051236	establishment of RNA localization	27/2053	166/18722	0.0235921303986729	0.0826344322195198	ZFP36/MX2/SLBP/RAN/HHEX/ZFP36L1/NPM1/HNRNPA3/HNRNPA1/NUP214/IGF2BP3/UPF3A/NXT1/MAGOHB/MYO1C/MAGOH/KHSRP/TPR/NCBP3/RANBP17/HNRNPA2B1/SRSF7/MVP/PABPN1/LRPPRC/NUP54/YBX1	27
GO:0014065	phosphatidylinositol 3-kinase signaling	24/2053	144/18722	0.0241925823388411	0.084658693103131	HCST/NCF1/PIK3AP1/FN1/KLF4/EGFR/FGR/JAK2/TNF/PTPN6/ZFP36L1/TREM2/PIK3R5/FLT1/C1QBP/MYDGF/GATA3/HCLS1/IGF1R/INSR/PTK2/PDGFA/IL18/PLEKHA1	24
GO:0046578	regulation of Ras protein signal transduction	30/2053	189/18722	0.0241982764453116	0.084658693103131	ARHGDIB/GPR65/STMN1/LPAR6/FBP1/ADGRG1/CYTH4/MET/TIMP2/ITGB1/NOTCH1/BCL6/DENND3/RASA1/KANK1/HRAS/RDX/NRP1/NOTCH2/CYTH1/NET1/EPS8/ARHGEF2/EPS8L2/FOXM1/GABARAP/CCDC125/ARFGEF3/RALGPS2/DYNLT1	30
GO:0002827	positive regulation of T-helper 1 type immune response	5/2053	16/18722	0.0244904725173592	0.0848889861953525	SLC11A1/IL1B/CCR2/IL27RA/IL18	5
GO:0006555	methionine metabolic process	5/2053	16/18722	0.0244904725173592	0.0848889861953525	ADI1/SMS/MTAP/MTR/ENOPH1	5
GO:0033631	cell-cell adhesion mediated by integrin	5/2053	16/18722	0.0244904725173592	0.0848889861953525	FERMT3/ITGA4/ITGB1/DPP4/PLPP3	5
GO:0044849	estrous cycle	5/2053	16/18722	0.0244904725173592	0.0848889861953525	PCNA/TRPM2/NCOR2/MDK/PTN	5
GO:0045838	positive regulation of membrane potential	5/2053	16/18722	0.0244904725173592	0.0848889861953525	GLRX/ANK3/STOML2/BAD/VCP	5
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	5/2053	16/18722	0.0244904725173592	0.0848889861953525	TNFRSF1B/TNF/IL1B/ADAM8/PACSIN3	5
GO:0060330	regulation of response to interferon-gamma	5/2053	16/18722	0.0244904725173592	0.0848889861953525	HSP90AB1/PARP9/NLRC5/PARP14/PPARG	5
GO:0060334	regulation of interferon-gamma-mediated signaling pathway	5/2053	16/18722	0.0244904725173592	0.0848889861953525	HSP90AB1/PARP9/NLRC5/PARP14/PPARG	5
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	5/2053	16/18722	0.0244904725173592	0.0848889861953525	TNFAIP3/TLR4/NFKBIA/SLC15A3/HSPA1A	5
GO:0072148	epithelial cell fate commitment	5/2053	16/18722	0.0244904725173592	0.0848889861953525	RARA/NOTCH1/NR2F2/NRP1/ESRP1	5
GO:0097202	activation of cysteine-type endopeptidase activity	5/2053	16/18722	0.0244904725173592	0.0848889861953525	PYCARD/PERP/IFI16/ASPH/BAD	5
GO:1904683	regulation of metalloendopeptidase activity	5/2053	16/18722	0.0244904725173592	0.0848889861953525	SORL1/MBP/TIMP3/STAT3/PICALM	5
GO:1905153	regulation of membrane invagination	5/2053	16/18722	0.0244904725173592	0.0848889861953525	NCKAP1L/CD300A/CD36/C3/TREM2	5
GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	5/2053	16/18722	0.0244904725173592	0.0848889861953525	PRKDC/PARP9/PNKP/DTX3L/RIF1	5
GO:2001044	regulation of integrin-mediated signaling pathway	5/2053	16/18722	0.0244904725173592	0.0848889861953525	TIMP1/FLNA/EMP2/LIMS1/CD63	5
GO:2001224	positive regulation of neuron migration	5/2053	16/18722	0.0244904725173592	0.0848889861953525	FLNA/SEMA6A/KIF20B/ARHGEF2/MDK	5
GO:0043407	negative regulation of MAP kinase activity	12/2053	59/18722	0.0246520160079021	0.0853503150879472	LYN/SORL1/CD300A/DUSP1/IRAK3/IL1B/GSTP1/PTPN6/BMP7/SH2B3/RGS2/PPARG	12
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	12/2053	59/18722	0.0246520160079021	0.0853503150879472	PTPRC/CD300A/LILRB4/SOCS3/PTPN6/SAMSN1/SH2B3/SUZ12/MVP/PARP14/VPS25/NCAPG2	12
GO:1900271	regulation of long-term synaptic potentiation	10/2053	46/18722	0.0250945077070103	0.0862234169489758	TYROBP/LILRB2/APP/NSG1/MME/CX3CR1/STAU1/NRGN/EIF2AK4/PTN	10
GO:0048017	inositol lipid-mediated signaling	29/2053	182/18722	0.0251419259471852	0.0862234169489758	HCST/NCF1/CSF1R/PIK3AP1/FN1/KLF4/EGFR/FGR/JAK2/TNF/PTAFR/ADAP2/PTPN6/PLCB2/ZFP36L1/TREM2/PIK3R5/FLT1/C1QBP/MYDGF/GATA3/HCLS1/EZR/IGF1R/INSR/PTK2/PDGFA/IL18/PLEKHA1	29
GO:0002604	regulation of dendritic cell antigen processing and presentation	4/2053	11/18722	0.0252634611660499	0.0862234169489758	CD68/FGL2/CD74/SLC11A1	4
GO:0002732	positive regulation of dendritic cell cytokine production	4/2053	11/18722	0.0252634611660499	0.0862234169489758	CLEC7A/SCIMP/DDX1/DDX58	4
GO:0003093	regulation of glomerular filtration	4/2053	11/18722	0.0252634611660499	0.0862234169489758	CYBA/EMP2/GJA1/GJA5	4
GO:0003174	mitral valve development	4/2053	11/18722	0.0252634611660499	0.0862234169489758	NOTCH1/GJA5/SOX4/EFNA1	4
GO:0006002	fructose 6-phosphate metabolic process	4/2053	11/18722	0.0252634611660499	0.0862234169489758	FBP1/HK3/HK2/GFPT1	4
GO:0009120	deoxyribonucleoside metabolic process	4/2053	11/18722	0.0252634611660499	0.0862234169489758	DPYD/DTYMK/TK1/PNP	4
GO:0009155	purine deoxyribonucleotide catabolic process	4/2053	11/18722	0.0252634611660499	0.0862234169489758	SAMHD1/NUDT15/PNP/DNPH1	4
GO:0019048	modulation by virus of host process	4/2053	11/18722	0.0252634611660499	0.0862234169489758	CD4/DAG1/PHB2/INSR	4
GO:0019372	lipoxygenase pathway	4/2053	11/18722	0.0252634611660499	0.0862234169489758	GPX1/ALOX5AP/ALOX5/HPGD	4
GO:0032610	interleukin-1 alpha production	4/2053	11/18722	0.0252634611660499	0.0862234169489758	CASP1/IL16/ISL1/S100A13	4
GO:0032650	regulation of interleukin-1 alpha production	4/2053	11/18722	0.0252634611660499	0.0862234169489758	CASP1/IL16/ISL1/S100A13	4
GO:0033327	Leydig cell differentiation	4/2053	11/18722	0.0252634611660499	0.0862234169489758	CCND1/SF1/MGST1/PLEKHA1	4
GO:0034115	negative regulation of heterotypic cell-cell adhesion	4/2053	11/18722	0.0252634611660499	0.0862234169489758	KLF4/MBP/MYADM/IL1RN	4
GO:0035457	cellular response to interferon-alpha	4/2053	11/18722	0.0252634611660499	0.0862234169489758	IFIT2/IFIT3/GATA3/TPR	4
GO:0035581	sequestering of extracellular ligand from receptor	4/2053	11/18722	0.0252634611660499	0.0862234169489758	FBN2/FBN1/CD46/LTBP1	4
GO:0045060	negative thymic T cell selection	4/2053	11/18722	0.0252634611660499	0.0862234169489758	PTPRC/CD74/DOCK2/GLI3	4
GO:0045654	positive regulation of megakaryocyte differentiation	4/2053	11/18722	0.0252634611660499	0.0862234169489758	HMGB2/SCIN/PITHD1/RCOR1	4
GO:0051561	positive regulation of mitochondrial calcium ion concentration	4/2053	11/18722	0.0252634611660499	0.0862234169489758	TGM2/FIS1/MCUR1/BNIP3	4
GO:0051657	maintenance of organelle location	4/2053	11/18722	0.0252634611660499	0.0862234169489758	ASPM/ARHGAP21/AKAP9/GPSM2	4
GO:0055015	ventricular cardiac muscle cell development	4/2053	11/18722	0.0252634611660499	0.0862234169489758	MEF2A/CDK1/FHL2/LMNA	4
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	4/2053	11/18722	0.0252634611660499	0.0862234169489758	KLF4/MBP/MYADM/IL1RN	4
GO:0072697	protein localization to cell cortex	4/2053	11/18722	0.0252634611660499	0.0862234169489758	GNAI1/EZR/GPSM2/EPB41	4
GO:2000615	regulation of histone H3-K9 acetylation	4/2053	11/18722	0.0252634611660499	0.0862234169489758	BRCA1/CHEK1/GATA3/ZNF451	4
GO:0045600	positive regulation of fat cell differentiation	13/2053	66/18722	0.0254479786377362	0.0868037929655582	ZFP36/ADIRF/METRNL/CEBPB/BMP7/ZFP36L1/LRP5/KLF5/CDS1/ID2/STK4/MAPK14/PPARG	13
GO:0019915	lipid storage	16/2053	87/18722	0.0261110624315256	0.0889299727887266	MSR1/TNF/IL1B/CD36/C3/NFKBIA/MEST/TREM2/HILPDA/PLIN2/SQLE/ITGAV/CDS1/HEXB/ASXL1/PPARG	16
GO:0001570	vasculogenesis	15/2053	80/18722	0.0261157686756227	0.0889299727887266	TGFB1/JUNB/VEGFA/ENG/NOTCH1/ZFP36L1/EMP2/RRAS/RASA1/AMOT/ITGAV/YAP1/RAP1A/TGFBR3/ITGB8	15
GO:0051303	establishment of chromosome localization	15/2053	80/18722	0.0261157686756227	0.0889299727887266	CENPF/CDT1/KPNB1/ACTR2/CDCA5/NUF2/KIF22/ACTR3/NDC80/EML4/NUDC/AURKB/CHMP4C/CDCA8/KIFC1	15
GO:0031331	positive regulation of cellular catabolic process	60/2053	427/18722	0.0264527400664972	0.0900263416897237	LAPTM5/MSN/TNFRSF1B/ZFP36/MTDH/ZFP36L2/TRIM22/HMGB1/LRRK2/LRP2/TNF/TNFAIP3/IL1B/APP/HMOX1/PLK3/PABPC1/HSP90AA1/SLC25A5/LIN28B/ZFP36L1/TREM2/ADAM8/PTK2B/HNRNPR/HAMP/P2RX7/BNIP3L/PHB2/PSMC3/BTG2/EXOSC8/TRIB1/RDX/PSMC1/SLC25A4/HNRNPD/RALB/KHSRP/BAG2/SVIP/TRIM38/VDAC1/PSMC2/DTX3L/MAGEF1/TMTC3/SCOC/PARK7/EZR/HSPA1A/BAD/BNIP3/AGO2/INSR/VCP/PLK2/GABARAP/PTK2/PACSIN3	60
GO:0035329	hippo signaling	9/2053	40/18722	0.0265890038603412	0.0903875485337378	AMOT/DLG5/YAP1/MOB1A/TEAD1/STK4/AMOTL2/MAPK14/AMOTL1	9
GO:0071276	cellular response to cadmium ion	9/2053	40/18722	0.0265890038603412	0.0903875485337378	CYBB/NCF1/FOS/EGFR/HMOX1/SOD1/MT1X/MT2A/JUN	9
GO:0032210	regulation of telomere maintenance via telomerase	11/2053	53/18722	0.0267426360459722	0.0907555521922132	PKIB/HNRNPA1/TCP1/CCT6A/CCT2/XRCC5/PNKP/CCT4/AURKB/CCT8/MAP3K4	11
GO:0045806	negative regulation of endocytosis	11/2053	53/18722	0.0267426360459722	0.0907555521922132	LILRB1/CD300A/LRPAP1/LGALS3/MCTP1/APOC1/RIN3/ITGAV/SDCBP/PICALM/PACSIN3	11
GO:0060966	regulation of gene silencing by RNA	11/2053	53/18722	0.0267426360459722	0.0907555521922132	ZFP36/TGFB1/EGFR/NEAT1/TNF/LIN28B/STAT3/NCOR2/AGO2/EIF4G1/PPARG	11
GO:1903322	positive regulation of protein modification by small protein conjugation or removal	23/2053	138/18722	0.0269059984097257	0.0912583326502849	LAPTM5/RASSF5/LRRK2/NPM1/HSPA5/BRCA1/UBE2C/UBB/BIRC3/FANCI/SPHK1/UBE2S/RPS2/UBE2D1/GNL3/SAE1/COMMD1/FKBP1A/SKP2/VCP/GABARAP/HUWE1/UBE2N	23
GO:0072659	protein localization to plasma membrane	42/2053	284/18722	0.0273331358441886	0.0926546977769105	TGFB1/FLNA/VAMP5/ACTB/ABI3/EGFR/CDH1/TNF/MYADM/GBP1/PRAM1/KRT18/NSG1/BSG/CSK/LAMA5/ITGB1/LGALS3/TREM2/EMP2/CCDC88A/TPBG/S100A10/RDX/CIB1/GOLGA4/ANK3/RAB3D/SPTBN1/RAP1A/GOPC/RHOG/RHOQ/EZR/DLG1/RILPL2/NUMB/PICALM/MYO5A/AP2M1/LDLRAP1/MAP7	42
GO:0002220	innate immune response activating cell surface receptor signaling pathway	6/2053	22/18722	0.0274560715813245	0.0927569985855556	TYROBP/FCN1/CLEC7A/LYN/LILRA2/SYK	6
GO:0035024	negative regulation of Rho protein signal transduction	6/2053	22/18722	0.0274560715813245	0.0927569985855556	STMN1/MET/ITGB1/BCL6/KANK1/CCDC125	6
GO:0043486	histone exchange	6/2053	22/18722	0.0274560715813245	0.0927569985855556	NASP/CENPW/ITGB3BP/MIS18A/RNF8/ACTR6	6
GO:0060343	trabecula formation	6/2053	22/18722	0.0274560715813245	0.0927569985855556	FBN2/ADAMTS1/FHL2/FKBP1A/TGFBR3/ADGRG6	6
GO:0060713	labyrinthine layer morphogenesis	6/2053	22/18722	0.0274560715813245	0.0927569985855556	SPINT1/SPINT2/SOCS3/BMP7/ZFP36L1/GRB2	6
GO:0061042	vascular wound healing	6/2053	22/18722	0.0274560715813245	0.0927569985855556	CXCR4/VEGFA/ALOX5/TNF/TNFAIP3/HPSE	6
GO:1904950	negative regulation of establishment of protein localization	22/2053	131/18722	0.0277214701420063	0.0932750216819136	UCP2/LRRK2/LMAN1/IL1B/CD36/CSK/RSAD2/RHBDF2/ERP29/IDH2/FERMT1/CHP1/BARD1/KLF7/FRMD4A/TXN/HADH/SVIP/GOPC/SP100/PARK7/MIDN	22
GO:0000096	sulfur amino acid metabolic process	8/2053	34/18722	0.0277337731134223	0.0932750216819136	COMT/ADI1/CDO1/SMS/MTAP/GCLM/MTR/ENOPH1	8
GO:0034724	DNA replication-independent nucleosome organization	8/2053	34/18722	0.0277337731134223	0.0932750216819136	NASP/CENPW/SUPT16H/ASF1B/RBBP4/HAT1/ITGB3BP/MIS18A	8
GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	8/2053	34/18722	0.0277337731134223	0.0932750216819136	OASL/IRF7/PHB2/BIRC3/C1QBP/USP15/PHB/DDX58	8
GO:0044319	wound healing, spreading of cells	8/2053	34/18722	0.0277337731134223	0.0932750216819136	CD44/FLNA/ITGA5/HBEGF/FERMT1/CD151/RHOA/FERMT2	8
GO:0070884	regulation of calcineurin-NFAT signaling cascade	8/2053	34/18722	0.0277337731134223	0.0932750216819136	CLEC7A/TNF/HOMER3/CHP1/CIB1/SLC9A1/FHL2/NFAT5	8
GO:0090505	epiboly involved in wound healing	8/2053	34/18722	0.0277337731134223	0.0932750216819136	CD44/FLNA/ITGA5/HBEGF/FERMT1/CD151/RHOA/FERMT2	8
GO:0098751	bone cell development	8/2053	34/18722	0.0277337731134223	0.0932750216819136	TYROBP/LILRB1/FBN1/PTPN6/FLI1/SH2B3/NOTCH2/WASF2	8
GO:0051851	modulation by host of symbiont process	12/2053	60/18722	0.0278424354264477	0.0935880182401603	CCL3/CCL4/NUCKS1/PPIB/IFI27/PSMC3/CX3CR1/HSPA8/PHB/EIF2AK4/JUN/CFL1	12
GO:0016053	organic acid biosynthetic process	46/2053	316/18722	0.0278703533797316	0.0936294066508341	CD74/ALOX5AP/MGST3/ALOX5/HACD3/IL1B/GSTP1/SDS/KYNU/SLC27A2/DPYD/GLUL/SYK/ACSS1/TECR/TBXAS1/PDK4/DHFR/BRCA1/ACADVL/SDSL/DEGS1/ADI1/ALDH1A1/CDO1/APOC1/FABP5/MTAP/LTA4H/NDUFAB1/OAT/ASS1/MID1IP1/ABHD2/PARK7/PYCR2/PTGES/PLOD2/SHMT1/MGLL/HACD4/ASNSD1/MTR/PRKAG2/SLC1A3/ENOPH1	46
GO:0006323	DNA packaging	31/2053	199/18722	0.0281434499269015	0.0944939561059927	NASP/HMGB1/HMGB2/HELLS/DNAJC9/TOP2A/CENPW/CDK1/SMC2/NUSAP1/NPM1/ASF1B/SET/SMC4/NAP1L1/RBBP4/MCM2/HAT1/CDCA5/ITGB3BP/NCAPD3/NCAPH/CHAF1A/SRPK1/KMT5A/MIS18A/NCAPG/RNF8/NAP1L4/SMARCA5/NCAPG2	31
GO:0001945	lymph vessel development	7/2053	28/18722	0.0282080652839949	0.0945521741362957	VEGFA/VASH1/SYK/NR2F2/SVEP1/PTPN14/FOXC1	7
GO:0032801	receptor catabolic process	7/2053	28/18722	0.0282080652839949	0.0945521741362957	LAPTM5/TGFB1/RNF43/DTX3L/ZNRF3/CAPN1/MYLIP	7
GO:0090200	positive regulation of release of cytochrome c from mitochondria	7/2053	28/18722	0.0282080652839949	0.0945521741362957	TNFSF10/PYCARD/PLAUR/PMAIP1/PDCD5/BAD/BNIP3	7
GO:0061180	mammary gland epithelium development	13/2053	67/18722	0.0285119399339596	0.0955173867134325	CSF1R/GPX1/JAK2/CEBPB/STAT6/CCND1/PHB2/VDR/GATA3/LRP5/BRCA2/ID2/TBX3	13
GO:0050679	positive regulation of epithelial cell proliferation	32/2053	207/18722	0.0287014595238302	0.0960986367985385	CYBA/C5AR1/HMGB1/EGFR/VEGFA/TNFAIP3/HMGB2/ITGA4/HMOX1/GRN/LAMB1/NRP2/GPBAR1/GLUL/JAML/NOTCH1/TNFSF12/NR4A1/LAMC1/CCND1/STAT5A/ID1/HRAS/NRP1/NOTCH2/STAT3/MYDGF/YAP1/BAD/MDK/NME1/PTN	32
GO:0007260	tyrosine phosphorylation of STAT protein	16/2053	88/18722	0.0287769184429927	0.0962975519564729	CSF1R/LYN/JAK2/TNF/SOCS3/PARP9/IL6R/SH2B3/ISL1/SUZ12/HDAC2/IL6ST/HCLS1/CSH1/PARP14/IL18	16
GO:0003151	outflow tract morphogenesis	14/2053	74/18722	0.0288445192782151	0.0964699641411876	MEF2C/VEGFA/LRP2/NRP2/BMP7/ENG/NOTCH1/GJA5/NRP1/ISL1/FOLR1/FOXC1/TGFBR3/TBX3	14
GO:0006096	glycolytic process	15/2053	81/18722	0.0289135947548271	0.0965933009626742	FBP1/APP/HK3/P2RX7/HK2/DDIT4/SLC2A6/ALDOA/LDHA/STAT3/ARL2/DHTKD1/INSR/GAPDH/PRKAG2	15
GO:0060968	regulation of gene silencing	15/2053	81/18722	0.0289135947548271	0.0965933009626742	ZFP36/TGFB1/EGFR/NEAT1/TNF/DNMT1/LIN28B/STAT3/TPR/NCOR2/AGO2/CDK2/TRIM28/EIF4G1/PPARG	15
GO:0051168	nuclear export	25/2053	154/18722	0.0291432014423452	0.0973061817774464	TGFB1/IL1B/RAN/CAMK1/HHEX/CALR/NPM1/HNRNPA1/NUP214/IFI27/CHP1/BARD1/PTPN14/CSE1L/TXN/NXT1/TPR/RANBP17/SP100/YWHAE/HNRNPA2B1/PARK7/PABPN1/CTDSPL2/HSPA9	25
GO:1990778	protein localization to cell periphery	48/2053	333/18722	0.0293590404654366	0.0979723263585202	TGFB1/FLNA/VAMP5/ACTB/ABI3/EGFR/CDH1/TNF/MYADM/GBP1/PRAM1/KRT18/NSG1/DAG1/BSG/CSK/LAMA5/ITGB1/LGALS3/TREM2/EMP2/CCDC88A/TPBG/S100A10/HRAS/RDX/CIB1/GOLGA4/ANK3/RAB3D/SPTBN1/RAP1A/GOPC/GNAI1/RHOG/RHOQ/EZR/DLG1/RILPL2/NUMB/PICALM/MYO5A/GPSM2/AP2M1/EPB41/CLSTN1/LDLRAP1/MAP7	48
GO:1904062	regulation of cation transmembrane transport	51/2053	357/18722	0.029386993772127	0.0980110965162657	CTSS/TMSB4X/FXYD5/CORO1A/CYBA/FLNA/LYN/SLC8A1/MEF2C/APP/FXYD3/CCR2/CXCL10/GLRX/IFNGR2/PTPN6/ITGB1/KCNAB2/TREM2/KCNQ1/PTK2B/HAMP/VMP1/TSPAN13/PHB2/CAMK2D/KCNMB1/KCNE3/CHP1/CALM2/C4orf3/ANK3/CD63/KCNN4/VDAC1/YWHAE/RGS2/SLC9A1/PARK7/COMMD1/DLG1/DMD/TCIRG1/FKBP1A/PTPN3/UBASH3B/AKAP9/CAPN1/HOMER1/ACTN4/COX17	51
GO:0002791	regulation of peptide secretion	31/2053	200/18722	0.029927816704595	0.0997593890153167	S100A8/HLA-DRB1/CD74/EGFR/UCP2/JAK2/ALOX5/TNF/IL1B/GLUL/MPC2/SERP1/DPP4/GJA1/HMGN3/UQCC2/TRPM2/KLF7/ISL1/SYT7/SOX4/HADH/ACSL4/SLC16A1/LRP5/PHPT1/BAD/TCIRG1/MIDN/ENSA/TM7SF3	31
GO:1904659	glucose transmembrane transport	19/2053	110/18722	0.0299906411324362	0.099913296387905	SLC2A3/TNF/IL1B/SLC2A1/C3/MEF2A/HK2/PRKCB/SLC2A6/FABP5/RAP1A/ASPSCR1/RHOQ/YES1/INSR/PEA15/MAPK14/PRKAG2/GPC3	19
GO:0001558	regulation of cell growth	58/2053	414/18722	0.0302002085131081	0.100555633228995	S100A8/CXCR4/BST2/CYBA/TGFB1/FN1/EGFR/SPP1/VEGFA/FBP1/CXCL16/SGK1/RBBP7/S100A9/SEMA4A/BCL6/ARHGAP4/NPM1/CDA/PTK2B/TMEM97/HAMP/TRPV2/SEMA6A/PPT1/CHPT1/GJA1/HBEGF/CAMK2D/BTG1/ITSN2/NRP1/SPHK1/RASGRP2/RHOA/CIB1/RPS6KA1/GOLGA4/TWF2/SDCBP/SEMA6D/SMARCA2/PARP2/CDKN2A/NET1/PHB/RGS2/SLC9A1/BCAR1/EI24/HSPA1A/CDKN1A/DNPH1/NDUFA13/EIF4G1/CLSTN1/DCBLD2/URI1	58
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	11/2053	54/18722	0.0303684675783066	0.100891918864806	PTPRC/HLA-F/NCKAP1L/HAVCR2/LILRB1/LILRB4/CD46/IL27RA/PTPN6/IL4I1/BCL6	11
GO:0006584	catecholamine metabolic process	11/2053	54/18722	0.0303684675783066	0.100891918864806	ITGB2/ITGAM/NR4A2/COMT/PNKD/SULT1A1/AKR1B1/EPAS1/GATA3/PARK7/GCH1	11
GO:0009712	catechol-containing compound metabolic process	11/2053	54/18722	0.0303684675783066	0.100891918864806	ITGB2/ITGAM/NR4A2/COMT/PNKD/SULT1A1/AKR1B1/EPAS1/GATA3/PARK7/GCH1	11
GO:0070228	regulation of lymphocyte apoptotic process	11/2053	54/18722	0.0303684675783066	0.100891918864806	CD74/TSC22D3/LGALS9/LYN/BTK/LGALS3/BCL6/ADAM8/SLC39A10/EFNA1/AURKB	11
GO:0007369	gastrulation	29/2053	185/18722	0.0305392865547295	0.101403275776633	ITGB2/DUSP1/FN1/KLF4/MBP/ITGA5/MYADM/ITGA4/WLS/DUSP2/IL1RN/LAMB1/DAG1/BMP7/ITGB1/ITGB4/COL4A2/RTF1/GJA1/AMOT/ITGB5/ITGAV/RPS6/LRP5/DUSP5/FOXC1/KDM6B/MMP15/GPC3	29
GO:0009135	purine nucleoside diphosphate metabolic process	18/2053	103/18722	0.0306385873384901	0.101620521852372	FBP1/APP/HK3/P2RX7/HK2/DDIT4/SLC2A6/ALDOA/LDHA/STAT3/ARL2/DHTKD1/DLG1/BAD/MPP1/INSR/GAPDH/PRKAG2	18
GO:0009179	purine ribonucleoside diphosphate metabolic process	18/2053	103/18722	0.0306385873384901	0.101620521852372	FBP1/APP/HK3/P2RX7/HK2/DDIT4/SLC2A6/ALDOA/LDHA/STAT3/ARL2/DHTKD1/DLG1/BAD/MPP1/INSR/GAPDH/PRKAG2	18
GO:0055007	cardiac muscle cell differentiation	21/2053	125/18722	0.0308568969930588	0.102244008963907	TGFB1/SLC8A1/MEF2C/VEGFA/ARRB2/MEF2A/RARA/CDK1/ITGB1/CALR/HAMP/ISL1/CACYBP/PARP2/OBSL1/RGS2/SLC9A1/FHL2/KDM6B/LMNA/TBX3	21
GO:0009167	purine ribonucleoside monophosphate metabolic process	9/2053	41/18722	0.0308606500389392	0.102244008963907	PAICS/PNP/GMPS/ADK/IMPDH2/DLG1/MPP1/AMPD3/PPAT	9
GO:0043547	positive regulation of GTPase activity	38/2053	255/18722	0.031032558680648	0.102756816823338	CCL3L3/CCL3/CCL4/GPR65/DOCK10/ITGA6/ADAP2/RGS1/TGM2/RGS10/PREX1/ITGB1/VAV1/PTK2B/ARHGAP25/ICAM1/GMIP/RASA1/ARHGAP27/EZH2/S100A10/LIMS1/HRAS/ADRB1/RASGRP2/ABR/DOCK9/RAP1A/NET1/FERMT2/RHOG/SYDE2/ECT2/CORO1C/EIF5/DOCK11/PICALM/CCDC125	38
GO:0046434	organophosphate catabolic process	25/2053	155/18722	0.0312555642010865	0.103438160621356	TYMP/SAMHD1/DUT/UPP1/HINT1/DPYD/GPCPD1/UNG/PLA2G7/ENTPD1/PDE4A/NUDT8/APOC1/NUDT15/PNP/PRDX6/IMPA2/IDH1/NUDT4/NUDT5/DCTPP1/AMPD3/SMPDL3A/VCP/DNPH1	25
GO:0014910	regulation of smooth muscle cell migration	16/2053	89/18722	0.0316392504267755	0.10390718407446	AIF1/SORL1/MEF2C/TLR4/GSTP1/DOCK4/S100A11/ADAMTS1/TRIB1/NRP1/RHOA/SEMA6D/FOXO4/APEX1/MDK/PDGFA	16
GO:0000097	sulfur amino acid biosynthetic process	5/2053	17/18722	0.0316397375506729	0.10390718407446	ADI1/CDO1/MTAP/MTR/ENOPH1	5
GO:0008340	determination of adult lifespan	5/2053	17/18722	0.0316397375506729	0.10390718407446	LRRK2/MSH2/MSH6/INPP5D/TFCP2L1	5
GO:0009151	purine deoxyribonucleotide metabolic process	5/2053	17/18722	0.0316397375506729	0.10390718407446	SAMHD1/NUDT15/PNP/ADK/DNPH1	5
GO:0010224	response to UV-B	5/2053	17/18722	0.0316397375506729	0.10390718407446	CRIP1/MME/MSH2/HMGN1/CDKN1A	5
GO:0015867	ATP transport	5/2053	17/18722	0.0316397375506729	0.10390718407446	SLC25A5/GJA1/SLC25A4/SLC25A17/SLC25A6	5
GO:0033623	regulation of integrin activation	5/2053	17/18722	0.0316397375506729	0.10390718407446	PLEK/PTGER4/FERMT1/JAM3/FERMT2	5
GO:0042953	lipoprotein transport	5/2053	17/18722	0.0316397375506729	0.10390718407446	MSR1/CD36/VMP1/PRKCB/PPARG	5
GO:0046827	positive regulation of protein export from nucleus	5/2053	17/18722	0.0316397375506729	0.10390718407446	IL1B/CAMK1/TPR/YWHAE/CTDSPL2	5
GO:0060977	coronary vasculature morphogenesis	5/2053	17/18722	0.0316397375506729	0.10390718407446	VEGFA/LRP2/NOTCH1/NRP1/TGFBR3	5
GO:0061158	3'-UTR-mediated mRNA destabilization	5/2053	17/18722	0.0316397375506729	0.10390718407446	ZFP36/ZFP36L2/ZFP36L1/HNRNPD/KHSRP	5
GO:0072673	lamellipodium morphogenesis	5/2053	17/18722	0.0316397375506729	0.10390718407446	CD44/PLEKHO1/KANK1/WASF2/CORO1C	5
GO:0090399	replicative senescence	5/2053	17/18722	0.0316397375506729	0.10390718407446	MME/CHEK1/CDKN2A/ERCC1/CDKN1A	5
GO:1904355	positive regulation of telomere capping	5/2053	17/18722	0.0316397375506729	0.10390718407446	PKIB/HNRNPD/PNKP/AURKB/MAP3K4	5
GO:0048015	phosphatidylinositol-mediated signaling	28/2053	178/18722	0.0317998342494617	0.104267168146062	HCST/NCF1/CSF1R/PIK3AP1/FN1/KLF4/EGFR/FGR/JAK2/TNF/PTAFR/PTPN6/PLCB2/ZFP36L1/TREM2/PIK3R5/FLT1/C1QBP/MYDGF/GATA3/HCLS1/EZR/IGF1R/INSR/PTK2/PDGFA/IL18/PLEKHA1	28
GO:0009988	cell-cell recognition	13/2053	68/18722	0.0318362420072644	0.104267168146062	MSN/CD9/HAVCR2/DOCK2/LGALS3/SPESP1/ALDOA/TCP1/FOLR1/CCT2/DLG1/CCT4/CCT8	13
GO:0034394	protein localization to cell surface	13/2053	68/18722	0.0318362420072644	0.104267168146062	TYROBP/FCN1/FLNA/TNF/HSP90AB1/KCNAB2/EMP2/JAM3/GOPC/VCL/COMMD1/PICALM/PTPRU	13
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	13/2053	68/18722	0.0318362420072644	0.104267168146062	CSF1R/LYN/JAK2/TNF/PARP9/IL6R/ISL1/HDAC2/IL6ST/HCLS1/CSH1/PARP14/IL18	13
GO:1902305	regulation of sodium ion transmembrane transport	13/2053	68/18722	0.0318362420072644	0.104267168146062	FXYD5/FXYD3/GLRX/KCNQ1/CAMK2D/CHP1/ANK3/SLC9A1/COMMD1/DLG1/DMD/PTPN3/ACTN4	13
GO:0006757	ATP generation from ADP	15/2053	82/18722	0.0319262420631882	0.104447902060594	FBP1/APP/HK3/P2RX7/HK2/DDIT4/SLC2A6/ALDOA/LDHA/STAT3/ARL2/DHTKD1/INSR/GAPDH/PRKAG2	15
GO:0043242	negative regulation of protein-containing complex disassembly	15/2053	82/18722	0.0319262420631882	0.104447902060594	CAPG/TNF/IRAK3/RDX/CIB1/TPX2/CKAP2/TWF2/SCIN/MID1IP1/SPTBN1/EPS8/ARHGEF2/LIMA1/TRIOBP	15
GO:0033077	T cell differentiation in thymus	14/2053	75/18722	0.032011920231108	0.104671128821061	PTPRC/CD74/MAFB/ZFP36L2/B2M/IL1B/DOCK2/PRKDC/SOD1/ZFP36L1/ADAM8/GATA3/RPS6/GLI3	14
GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	19/2053	111/18722	0.032597595570222	0.106327396321157	HCST/NCF1/PIK3AP1/FN1/KLF4/EGFR/FGR/JAK2/TNF/PTPN6/TREM2/FLT1/MYDGF/HCLS1/IGF1R/INSR/PTK2/PDGFA/IL18	19
GO:0009119	ribonucleoside metabolic process	8/2053	35/18722	0.0326070682051548	0.106327396321157	APOBEC3A/UPP1/CDA/APOBEC3G/APOBEC3C/MTAP/PNP/ADK	8
GO:0040001	establishment of mitotic spindle localization	8/2053	35/18722	0.0326070682051548	0.106327396321157	ITGB1/NUSAP1/MAD2L1/GJA1/KPNB1/NDC80/GPSM2/DYNLT1	8
GO:0090504	epiboly	8/2053	35/18722	0.0326070682051548	0.106327396321157	CD44/FLNA/ITGA5/HBEGF/FERMT1/CD151/RHOA/FERMT2	8
GO:0106056	regulation of calcineurin-mediated signaling	8/2053	35/18722	0.0326070682051548	0.106327396321157	CLEC7A/TNF/HOMER3/CHP1/CIB1/SLC9A1/FHL2/NFAT5	8
GO:0002715	regulation of natural killer cell mediated immunity	10/2053	48/18722	0.0329793268874911	0.107366229693406	HLA-B/HLA-A/HLA-F/LGALS9/HLA-E/HAVCR2/LILRB1/ARRB2/CADM1/VAV1	10
GO:1905710	positive regulation of membrane permeability	10/2053	48/18722	0.0329793268874911	0.107366229693406	LAPTM5/SLC25A5/BNIP3L/JAM3/HEBP2/CHCHD10/SLC9A1/HSPA1A/NMT1/BNIP3	10
GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	10/2053	48/18722	0.0329793268874911	0.107366229693406	RPS7/HSP90AB1/RPL5/RPL23/PBK/SMARCC1/SDCBP/USP14/SVIP/PARK7	10
GO:0051048	negative regulation of secretion	27/2053	171/18722	0.0331017555232378	0.107706362873876	CD74/HLA-F/TNFRSF1B/SPI1/LGALS9/NCKAP1L/CD84/LILRB1/CD300A/UCP2/IL1B/HMOX1/CCR2/NOTCH1/RSAD2/COMT/PNKD/RHBDF2/ERP29/IDH2/GJA1/GNAI2/KLF7/FRMD4A/HADH/RAP1A/MIDN	27
GO:0034284	response to monosaccharide	34/2053	225/18722	0.033238091323413	0.108091353897278	TXNIP/HLA-DRB1/LGALS1/CYBA/SLC8A1/UCP2/SOD2/SERPINF1/GSTP1/NAMPT/KRT18/GLUL/MPC2/TREM2/PTK2B/ICAM1/CTSV/SLC29A1/GJA1/HMGN3/KLF7/LDHA/RHOA/SOX4/GCLM/LRP5/FIS1/PHPT1/BAD/IGF1R/TRA2B/ENSA/NME1/CCDC186	34
GO:0032963	collagen metabolic process	18/2053	104/18722	0.0333903154182408	0.108527569073372	VIM/CTSS/TGFB1/CST3/CTSB/CTSL/ARRB2/RUNX1/CIITA/ITGB1/ENG/SERPINH1/HDAC2/RGCC/RAP1A/P3H1/MMP15/SUCO	18
GO:0035296	regulation of tube diameter	23/2053	141/18722	0.0335924671747406	0.108856858083061	SLC8A1/GPX1/EGFR/SOD2/KLF2/DOCK4/SOD1/TBXAS1/ATP2B1/ICAM1/GJA1/KCNMB1/HRH2/GJA5/SLC6A4/ADRB1/SCPEP1/RHOA/GCLM/SOD3/RGS2/GCH1/FOXC1	23
GO:0097746	blood vessel diameter maintenance	23/2053	141/18722	0.0335924671747406	0.108856858083061	SLC8A1/GPX1/EGFR/SOD2/KLF2/DOCK4/SOD1/TBXAS1/ATP2B1/ICAM1/GJA1/KCNMB1/HRH2/GJA5/SLC6A4/ADRB1/SCPEP1/RHOA/GCLM/SOD3/RGS2/GCH1/FOXC1	23
GO:0009416	response to light stimulus	46/2053	320/18722	0.0337134282869439	0.108856858083061	TIMP1/CRIP1/DUSP1/FOS/GPX1/EGFR/PCNA/PARP1/APP/NR2F6/FEN1/CARD16/MME/ITGB1/NPM1/CCND1/MSH2/DTL/PBK/CHEK1/USP1/MSH6/DDB1/TRIAP1/SCARA3/POLD3/BHLHE40/BRCA2/HMGN1/GNA11/EIF2AK4/TIPIN/BEST1/COPS3/ERCC1/NMT1/CDKN1A/CDS1/AURKB/ID2/PTN/MAP3K4/TP53I13/UBE4B/SLC1A3/MEIS2	46
GO:0090087	regulation of peptide transport	31/2053	202/18722	0.0337560894544366	0.108856858083061	S100A8/HLA-DRB1/CD74/EGFR/UCP2/JAK2/ALOX5/TNF/IL1B/GLUL/MPC2/SERP1/DPP4/GJA1/HMGN3/UQCC2/TRPM2/KLF7/ISL1/SYT7/SOX4/HADH/ACSL4/SLC16A1/LRP5/PHPT1/BAD/TCIRG1/MIDN/ENSA/TM7SF3	31
GO:1903046	meiotic cell cycle process	31/2053	202/18722	0.0337560894544366	0.108856858083061	TOP2A/SMC2/RAD51AP1/CALR/RAD51/CCNE1/ASPM/SMC4/UBB/RAD51C/MSH6/CKS2/ACTR2/FBXO5/RAD21/CCNE2/NUF2/MND1/NCAPD3/BRCA2/FANCD2/RAD50/PSMC3IP/ACTR3/TTK/ERCC1/TOP2B/ING2/BUB1B/FIGNL1/FANCA	31
GO:0001773	myeloid dendritic cell activation	7/2053	29/18722	0.0337736917358428	0.108856858083061	SPI1/PYCARD/HAVCR2/HMGB1/DOCK2/NOTCH2/ITGB8	7
GO:0002360	T cell lineage commitment	7/2053	29/18722	0.0337736917358428	0.108856858083061	CTSL/PRKDC/STAT6/IL6R/SPN/RHOA/STAT3	7
GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	7/2053	29/18722	0.0337736917358428	0.108856858083061	EGFR/CKS1B/CDC6/CCND1/CCND3/CKS2/RGCC	7
GO:0050686	negative regulation of mRNA processing	7/2053	29/18722	0.0337736917358428	0.108856858083061	NPM1/C1QBP/BARD1/SRSF10/SRSF7/RBMX/SRSF4	7
GO:0060969	negative regulation of gene silencing	7/2053	29/18722	0.0337736917358428	0.108856858083061	TGFB1/NEAT1/TNF/LIN28B/STAT3/NCOR2/PPARG	7
GO:0002363	alpha-beta T cell lineage commitment	6/2053	23/18722	0.0338000544347905	0.108856858083061	CTSL/STAT6/IL6R/SPN/RHOA/STAT3	6
GO:0006541	glutamine metabolic process	6/2053	23/18722	0.0338000544347905	0.108856858083061	GLUL/GMPS/NIT2/ASNSD1/GFPT1/PPAT	6
GO:0010888	negative regulation of lipid storage	6/2053	23/18722	0.0338000544347905	0.108856858083061	TNF/NFKBIA/TREM2/ITGAV/ASXL1/PPARG	6
GO:0051131	chaperone-mediated protein complex assembly	6/2053	23/18722	0.0338000544347905	0.108856858083061	HSPD1/HSP90AA1/HSP90AB1/PSMG1/CCT2/HSPA1A	6
GO:0051457	maintenance of protein location in nucleus	6/2053	23/18722	0.0338000544347905	0.108856858083061	BARD1/TXN/ARL2/CHCHD10/SP100/PARK7	6
GO:0051882	mitochondrial depolarization	6/2053	23/18722	0.0338000544347905	0.108856858083061	TSPO/LRRK2/CASP1/PARP1/IFI6/GCLM	6
GO:0072677	eosinophil migration	6/2053	23/18722	0.0338000544347905	0.108856858083061	CCL3/CCL4/CD300A/PTGER4/LGALS3/ADAM8	6
GO:0071824	protein-DNA complex subunit organization	36/2053	241/18722	0.0339448042672489	0.109264391418183	NASP/HMGB1/HMGB2/HELLS/GMNN/DNAJC9/CENPW/CENPF/SUPT16H/RPL23/NPM1/RAD51/ASF1B/CENPN/SET/NAP1L1/CDT1/RBBP4/MCM2/RAD51C/HAT1/CENPK/ITGB3BP/CENPH/HMGA1/SMARCC1/CHAF1A/POLE3/CDC45/MIS18A/RNF8/BDP1/NAP1L4/ACTR6/SMARCA5/KNTC1	36
GO:1990868	response to chemokine	17/2053	97/18722	0.0341025705501151	0.109654567685258	CCL3L3/CXCR4/CCL3/CCL4/DUSP1/CCR1/CCR2/CXCL10/CCRL2/TREM2/PTK2B/SH2B3/CX3CR1/CXCL8/RHOA/CIB1/FOXC1	17
GO:1990869	cellular response to chemokine	17/2053	97/18722	0.0341025705501151	0.109654567685258	CCL3L3/CXCR4/CCL3/CCL4/DUSP1/CCR1/CCR2/CXCL10/CCRL2/TREM2/PTK2B/SH2B3/CX3CR1/CXCL8/RHOA/CIB1/FOXC1	17
GO:0001755	neural crest cell migration	11/2053	55/18722	0.0343316009580523	0.109769444932637	FN1/NRP2/BMP7/LAMA5/SEMA4A/SEMA6A/NRP1/ISL1/FOLR1/SEMA6D/CORO1C	11
GO:0031398	positive regulation of protein ubiquitination	20/2053	119/18722	0.0343697139692443	0.109769444932637	LAPTM5/RASSF5/LRRK2/NPM1/HSPA5/BRCA1/UBE2C/UBB/BIRC3/FANCI/SPHK1/UBE2S/RPS2/UBE2D1/COMMD1/FKBP1A/SKP2/GABARAP/HUWE1/UBE2N	20
GO:0002903	negative regulation of B cell apoptotic process	4/2053	12/18722	0.0346741399033411	0.109769444932637	CD74/BCL6/SLC39A10/AURKB	4
GO:0006216	cytidine catabolic process	4/2053	12/18722	0.0346741399033411	0.109769444932637	APOBEC3A/CDA/APOBEC3G/APOBEC3C	4
GO:0009086	methionine biosynthetic process	4/2053	12/18722	0.0346741399033411	0.109769444932637	ADI1/MTAP/MTR/ENOPH1	4
GO:0009265	2'-deoxyribonucleotide biosynthetic process	4/2053	12/18722	0.0346741399033411	0.109769444932637	DUT/TYMS/DTYMK/ADK	4
GO:0009886	post-embryonic animal morphogenesis	4/2053	12/18722	0.0346741399033411	0.109769444932637	EFEMP1/FBN1/HMGN1/MYO7A	4
GO:0009972	cytidine deamination	4/2053	12/18722	0.0346741399033411	0.109769444932637	APOBEC3A/CDA/APOBEC3G/APOBEC3C	4
GO:0032621	interleukin-18 production	4/2053	12/18722	0.0346741399033411	0.109769444932637	CD84/TLR2/GBP5/NLRP12	4
GO:0032661	regulation of interleukin-18 production	4/2053	12/18722	0.0346741399033411	0.109769444932637	CD84/TLR2/GBP5/NLRP12	4
GO:0034333	adherens junction assembly	4/2053	12/18722	0.0346741399033411	0.109769444932637	ACTB/DLG5/JAM3/VCL	4
GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	4/2053	12/18722	0.0346741399033411	0.109769444932637	SYK/COL4A2/COL4A1/UBASH3B	4
GO:0043129	surfactant homeostasis	4/2053	12/18722	0.0346741399033411	0.109769444932637	VEGFA/CTSH/OAS1/EPAS1	4
GO:0043383	negative T cell selection	4/2053	12/18722	0.0346741399033411	0.109769444932637	PTPRC/CD74/DOCK2/GLI3	4
GO:0046087	cytidine metabolic process	4/2053	12/18722	0.0346741399033411	0.109769444932637	APOBEC3A/CDA/APOBEC3G/APOBEC3C	4
GO:0046385	deoxyribose phosphate biosynthetic process	4/2053	12/18722	0.0346741399033411	0.109769444932637	DUT/TYMS/DTYMK/ADK	4
GO:0051095	regulation of helicase activity	4/2053	12/18722	0.0346741399033411	0.109769444932637	IFIT1/MSH2/MCM2/MSH6	4
GO:0070586	cell-cell adhesion involved in gastrulation	4/2053	12/18722	0.0346741399033411	0.109769444932637	KLF4/MBP/MYADM/IL1RN	4
GO:0072182	regulation of nephron tubule epithelial cell differentiation	4/2053	12/18722	0.0346741399033411	0.109769444932637	STAT1/CD24/GATA3/YAP1	4
GO:0072537	fibroblast activation	4/2053	12/18722	0.0346741399033411	0.109769444932637	RPS6KA1/RGCC/GCLM/IL17RA	4
GO:0072683	T cell extravasation	4/2053	12/18722	0.0346741399033411	0.109769444932637	ITGAL/CCR2/IL27RA/ICAM1	4
GO:0090331	negative regulation of platelet aggregation	4/2053	12/18722	0.0346741399033411	0.109769444932637	CD9/SH2B3/C1QTNF1/UBASH3B	4
GO:0098911	regulation of ventricular cardiac muscle cell action potential	4/2053	12/18722	0.0346741399033411	0.109769444932637	DSP/DSG2/DSC2/DLG1	4
GO:1901298	regulation of hydrogen peroxide-mediated programmed cell death	4/2053	12/18722	0.0346741399033411	0.109769444932637	MET/PAWR/PARK7/TRAP1	4
GO:2000105	positive regulation of DNA-dependent DNA replication	4/2053	12/18722	0.0346741399033411	0.109769444932637	CDT1/DBF4/STOML2/E2F7	4
GO:2000508	regulation of dendritic cell chemotaxis	4/2053	12/18722	0.0346741399033411	0.109769444932637	SPI1/LGALS9/CALR/C1QBP	4
GO:2001204	regulation of osteoclast development	4/2053	12/18722	0.0346741399033411	0.109769444932637	TYROBP/LILRB1/FBN1/NOTCH2	4
GO:0030522	intracellular receptor signaling pathway	39/2053	265/18722	0.0346900442454884	0.109769444932637	JAK2/OASL/KLF2/TNFAIP3/TLR4/NR4A2/PARP1/IRF7/NR2F6/NFKBIA/RARA/NR2F2/CALR/NR4A1/BRCA1/PHB2/EZH2/SLC15A3/BIRC3/C1QBP/ISL1/RHOA/FABP5/USP15/STAT3/VDR/TRIM24/NCOR2/YAP1/PHB/PARK7/HSPA1A/DDX58/SKP2/PKN1/DCBLD2/ASXL1/ACTN4/PPARG	39
GO:0046031	ADP metabolic process	16/2053	90/18722	0.034705439506202	0.109769444932637	FBP1/APP/HK3/P2RX7/HK2/DDIT4/SLC2A6/ALDOA/LDHA/STAT3/ARL2/DHTKD1/BAD/INSR/GAPDH/PRKAG2	16
GO:0097581	lamellipodium organization	16/2053	90/18722	0.034705439506202	0.109769444932637	CD44/WAS/RAC2/ABI3/PLEKHO1/ITGB1/SPATA13/CCDC88A/KANK1/ACTR2/TWF2/ACTR3/WASF2/VCL/VAV3/CORO1C	16
GO:1904705	regulation of vascular associated smooth muscle cell proliferation	16/2053	90/18722	0.034705439506202	0.109769444932637	MEF2C/SOD2/JAK2/TNF/GSTP1/HMOX1/DNMT1/GJA1/ADAMTS1/GNAI2/HPGD/RHOA/JUN/CDKN1A/LDLRAP1/PPARG	16
GO:0001508	action potential	22/2053	134/18722	0.0347791220276342	0.109944537495155	FLNA/SLC8A1/CD36/DSP/KCNAB2/KCNQ1/DSG2/GNA15/GJA1/CAMK2D/KCNE3/GJA5/DSC2/ANK3/GNA11/YWHAE/SLC9A1/USP53/DLG1/DMD/PTPN3/AKAP9	22
GO:0006470	protein dephosphorylation	41/2053	281/18722	0.0350089239914783	0.110612714033107	PTPRC/TGFB1/NCKAP1L/LILRB2/CD300A/DUSP1/JAK2/LRRK2/HSP90B1/TNF/PGP/HSP90AB1/PTPN6/PPIA/LGALS3/CD33/SLC39A10/CTDSPL/PPM1G/GNAI2/DAPP1/CALM2/PTPN14/DUSP14/DUSP18/PTPRF/DUSP5/YWHAE/CAMK2G/MASTL/PHPT1/DLG1/PTP4A2/FKBP1A/PPP1R15A/ENSA/PTPN3/UBASH3B/CTDSPL2/PTPRU/ILKAP	41
GO:0042391	regulation of membrane potential	60/2053	434/18722	0.0351720315688941	0.111069573375455	TSPO/FLNA/SLC8A1/MEF2C/UCP2/SOD2/LRRK2/CASP1/PARP1/CD36/DSP/APP/ARRB2/GLRX/SOD1/KCNAB2/IFI6/TREM2/KCNQ1/PTK2B/DSG2/KCNK6/P2RX7/GNA15/SLC29A1/BNIP3L/GJA1/CAMK2D/KCNE3/UBB/PMAIP1/GJA5/ADRB1/DSC2/CLIC1/SLC25A36/PRDX3/GCLM/ANK3/KCNN4/HEBP2/STOML2/CHCHD10/GNA11/YWHAE/JUN/SLC9A1/PARK7/GABRE/USP53/DLG1/BAD/DMD/BNIP3/CHRNB1/CHRNA5/VCP/PTPN3/PTN/AKAP9	60
GO:0072028	nephron morphogenesis	14/2053	76/18722	0.035424485624247	0.111653718016186	VEGFA/STAT1/MAGED1/BMP7/LAMA5/TACSTD2/AHI1/GATA3/PBX1/LGR4/DLG1/GLI3/IRX2/GPC3	14
GO:0009145	purine nucleoside triphosphate biosynthetic process	13/2053	69/18722	0.0354314465171362	0.111653718016186	TMSB4X/TGFB1/PARP1/TREM2/ALDOA/STAT3/STOML2/NME4/ADK/IMPDH2/VCP/NME1/PRKAG2	13
GO:0060193	positive regulation of lipase activity	13/2053	69/18722	0.0354314465171362	0.111653718016186	C5AR1/CD86/EGFR/PTAFR/S1PR4/PLCB2/GNA15/PHB2/FLT1/HRAS/RHOA/PHB/ARL1	13
GO:1904377	positive regulation of protein localization to cell periphery	13/2053	69/18722	0.0354314465171362	0.111653718016186	EGFR/TNF/ITGB1/LGALS3/TREM2/CIB1/SPTBN1/GNAI1/RHOG/EZR/DLG1/GPSM2/EPB41	13
GO:0035150	regulation of tube size	23/2053	142/18722	0.0360770259530979	0.113628428198734	SLC8A1/GPX1/EGFR/SOD2/KLF2/DOCK4/SOD1/TBXAS1/ATP2B1/ICAM1/GJA1/KCNMB1/HRH2/GJA5/SLC6A4/ADRB1/SCPEP1/RHOA/GCLM/SOD3/RGS2/GCH1/FOXC1	23
GO:0048568	embryonic organ development	59/2053	427/18722	0.0368029801483251	0.11585408231372	TGFB1/MAFB/MEF2C/EFEMP1/SPINT1/SPINT2/FBN2/JUNB/VEGFA/FBN1/PHLDA2/TNF/CEBPB/SOCS3/VASH1/SOD1/RARA/BMP7/ENG/NOTCH1/NR2F2/ZFP36L1/KCNQ1/SH2B3/SLC39A1/CXCL8/KRT8/MFAP5/EPAS1/ASCL2/TFAP2A/NOTCH2/AHI1/GATA3/FOLR1/PBX1/GRB2/ID3/EFNA1/YAP1/TEAD1/ATP6V1B1/DLG1/ERCC1/RAD23B/TRA2B/GLI3/ID2/STK4/FOXC1/TRIM28/TRIOBP/TBX3/MBD2/PDGFA/MBD3/COBL/E2F7/MYO7A	59
GO:0009914	hormone transport	44/2053	306/18722	0.0369671090708114	0.116227928652665	HLA-DRB1/LYN/EGFR/UCP2/SPP1/JAK2/RETN/ALOX5/TNF/IL1B/IL1RN/BTK/GLUL/MPC2/SERP1/DPP4/KCNQ1/GJA1/FAM3B/HMGN3/UQCC2/TRPM2/KLF7/ISL1/SYT7/SOX4/HADH/GATA3/SNX4/ACSL4/SLC16A1/LRP5/CYB5R4/CAMK2G/PARK7/PHPT1/BAD/TCIRG1/MIDN/C1QTNF1/ENSA/TBX3/TM7SF3/CCDC186	44
GO:0006605	protein targeting	45/2053	314/18722	0.0369798526329895	0.116227928652665	LAPTM5/TSPO/ITGB2/NCF1/SORL1/RAC2/LRRK2/ITGAM/TCAF1/HOMER3/LMAN1/HSPD1/HSP90AA1/HSPA5/ZDHHC12/BNIP3L/HSPA8/TIMM13/HRAS/CHP1/SPCS2/CIB1/TOMM40/PARD3/PDCD5/MYO1C/SDCBP/ANK3/RAB3IP/AP1S3/TOMM34/ICMT/SEC63/DNAJC19/VPS13C/SAE1/FIS1/SGTB/SIL1/PMPCB/NACA/GABARAP/NUP54/HUWE1/NDUFA13	45
GO:0046394	carboxylic acid biosynthetic process	45/2053	314/18722	0.0369798526329895	0.116227928652665	CD74/ALOX5AP/MGST3/ALOX5/HACD3/IL1B/GSTP1/SDS/KYNU/SLC27A2/DPYD/GLUL/SYK/ACSS1/TECR/TBXAS1/PDK4/DHFR/BRCA1/ACADVL/SDSL/DEGS1/ADI1/ALDH1A1/APOC1/FABP5/MTAP/LTA4H/NDUFAB1/OAT/ASS1/MID1IP1/ABHD2/PARK7/PYCR2/PTGES/PLOD2/SHMT1/MGLL/HACD4/ASNSD1/MTR/PRKAG2/SLC1A3/ENOPH1	45
GO:0032411	positive regulation of transporter activity	20/2053	120/18722	0.0371495152244546	0.116700047825512	CTSS/TMSB4X/TCAF1/PTAFR/SGK1/CCR2/GLRX/IFNGR2/TREM2/VMP1/KCNE3/CHP1/CALM2/ANK3/SLC9A1/PARK7/DMD/AKAP9/ACTN4/COX17	20
GO:0061337	cardiac conduction	17/2053	98/18722	0.0372008807048383	0.116800253390387	FLNA/SLC8A1/DSP/MEF2A/ATP2B1/KCNQ1/DSG2/GJA1/CAMK2D/KCNE3/GJA5/ISL1/DSC2/CALM2/YWHAE/SLC9A1/AKAP9	17
GO:0018198	peptidyl-cysteine modification	10/2053	49/18722	0.0375094600538151	0.117584514275283	S100A8/S100A9/ZDHHC12/ADH5/TXN/PRDX3/RAB3D/PARK7/DMD/GAPDH	10
GO:0070849	response to epidermal growth factor	10/2053	49/18722	0.0375094600538151	0.117584514275283	ZFP36/ZFP36L2/EGFR/MCM7/GSTP1/ZFP36L1/ID1/TPR/NCL/FOXC1	10
GO:0072091	regulation of stem cell proliferation	10/2053	49/18722	0.0375094600538151	0.117584514275283	PTPRC/FBLN1/HMGB2/ZFP36L1/CCNE1/GJA1/FERMT1/YAP1/FERMT2/TBX3	10
GO:0051492	regulation of stress fiber assembly	16/2053	91/18722	0.0379826018788779	0.118788301782254	WAS/GPR65/STMN1/PTGER4/MET/CCDC88A/TACSTD2/S100A10/NRP1/RHOA/RGCC/TJP1/FERMT2/WASF2/PFN1/SLC9A1	16
GO:0060191	regulation of lipase activity	16/2053	91/18722	0.0379826018788779	0.118788301782254	C5AR1/CD86/EGFR/PTAFR/S1PR4/PLCB2/GNA15/PHB2/FLT1/PPT1/HRAS/APOC1/RHOA/PHB/RGS2/ARL1	16
GO:1990874	vascular associated smooth muscle cell proliferation	16/2053	91/18722	0.0379826018788779	0.118788301782254	MEF2C/SOD2/JAK2/TNF/GSTP1/HMOX1/DNMT1/GJA1/ADAMTS1/GNAI2/HPGD/RHOA/JUN/CDKN1A/LDLRAP1/PPARG	16
GO:0045191	regulation of isotype switching	8/2053	36/18722	0.0380320546206182	0.118788301782254	PTPRC/TGFB1/STAT6/IL27RA/BCL6/MSH2/RIF1/TFRC	8
GO:0051385	response to mineralocorticoid	8/2053	36/18722	0.0380320546206182	0.118788301782254	CYBB/CYBA/FOS/PARP1/ATP2B1/CCND1/FOSB/CDKN1A	8
GO:0060338	regulation of type I interferon-mediated signaling pathway	8/2053	36/18722	0.0380320546206182	0.118788301782254	ISG15/SAMHD1/IRF7/HSP90AB1/PTPN6/OAS1/NLRC5/STAT2	8
GO:1901658	glycosyl compound catabolic process	8/2053	36/18722	0.0380320546206182	0.118788301782254	APOBEC3A/UPP1/DPYD/CDA/APOBEC3G/APOBEC3C/FUCA1/PNP	8
GO:0002090	regulation of receptor internalization	11/2053	56/18722	0.0386455597374846	0.12039115183017	VEGFA/ARRB2/LRPAP1/SYK/RIN3/AHI1/SDCBP/CD63/NUMB/INSR/AP2M1	11
GO:0046622	positive regulation of organ growth	11/2053	56/18722	0.0386455597374846	0.12039115183017	MEF2C/SASH3/CDK1/SERP1/NOTCH1/HAMP/YAP1/PARP2/TGFBR3/BASP1/MAPK14	11
GO:0051058	negative regulation of small GTPase mediated signal transduction	11/2053	56/18722	0.0386455597374846	0.12039115183017	STMN1/FBP1/MET/TIMP2/ITGB1/BCL6/ARHGAP25/RASA1/KANK1/CD2AP/CCDC125	11
GO:0071385	cellular response to glucocorticoid stimulus	11/2053	56/18722	0.0386455597374846	0.12039115183017	ZFP36/ZFP36L2/EGFR/SERPINF1/GSTP1/ZFP36L1/ATP2B1/ICAM1/DDIT4/ISL1/ASS1	11
GO:1904645	response to amyloid-beta	11/2053	56/18722	0.0386455597374846	0.12039115183017	TLR4/PARP1/CD36/APP/ITGA4/NAMPT/TLR6/TREM2/ICAM1/GJA1/IGF1R	11
GO:0031023	microtubule organizing center organization	23/2053	143/18722	0.0386958641236296	0.1204853060414	RANBP1/CDK1/NPM1/BRCA1/CHEK1/CEP152/ARL2/ATF5/SLC16A1/BRCA2/HAUS8/NDC80/HAUS1/PARD6B/CDK2/CENPJ/SASS6/CHMP4C/PLK2/CCP110/SAC3D1/KIF11/XRCC2	23
GO:0032418	lysosome localization	14/2053	77/18722	0.0390910518266014	0.12165265091266	LGALS9/CD84/LYN/LAT2/CD300A/RAC2/FGR/HMOX1/STXBP2/ADGRE2/BTK/SYK/SNX4/S100A13	14
GO:0030072	peptide hormone secretion	35/2053	236/18722	0.0395267307551925	0.122944730187224	HLA-DRB1/EGFR/UCP2/JAK2/ALOX5/TNF/IL1B/IL1RN/GLUL/MPC2/SERP1/DPP4/GJA1/FAM3B/HMGN3/UQCC2/TRPM2/KLF7/ISL1/SYT7/SOX4/HADH/ACSL4/SLC16A1/LRP5/CYB5R4/CAMK2G/PARK7/PHPT1/BAD/TCIRG1/MIDN/ENSA/TM7SF3/CCDC186	35
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	5/2053	18/18722	0.0399651553954219	0.123337852045023	PTPRC/TNF/CD46/PTPN6/TREM2	5
GO:0006595	polyamine metabolic process	5/2053	18/18722	0.0399651553954219	0.123337852045023	OAZ1/SAT1/SMS/SRM/SAT2	5
GO:0010985	negative regulation of lipoprotein particle clearance	5/2053	18/18722	0.0399651553954219	0.123337852045023	LRPAP1/CSK/APOC1/KHSRP/MYLIP	5
GO:0021534	cell proliferation in hindbrain	5/2053	18/18722	0.0399651553954219	0.123337852045023	C5AR1/PSMG1/SLC6A4/ATF5/RERE	5
GO:0030730	sequestering of triglyceride	5/2053	18/18722	0.0399651553954219	0.123337852045023	TNF/IL1B/TREM2/PLIN2/PPARG	5
GO:0034162	toll-like receptor 9 signaling pathway	5/2053	18/18722	0.0399651553954219	0.123337852045023	PIK3AP1/HAVCR2/HMGB1/RSAD2/UNC93B1	5
GO:0035743	CD4-positive, alpha-beta T cell cytokine production	5/2053	18/18722	0.0399651553954219	0.123337852045023	IL1B/NLRP3/RSAD2/GATA3/IL18	5
GO:0044872	lipoprotein localization	5/2053	18/18722	0.0399651553954219	0.123337852045023	MSR1/CD36/VMP1/PRKCB/PPARG	5
GO:0046112	nucleobase biosynthetic process	5/2053	18/18722	0.0399651553954219	0.123337852045023	PAICS/UMPS/GMPS/SHMT1/PPAT	5
GO:0060391	positive regulation of SMAD protein signal transduction	5/2053	18/18722	0.0399651553954219	0.123337852045023	TGFB1/JAK2/PARP1/RBPMS/PPARG	5
GO:0071800	podosome assembly	5/2053	18/18722	0.0399651553954219	0.123337852045023	MSN/LCP1/HCK/TNF/RHOA	5
GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	5/2053	18/18722	0.0399651553954219	0.123337852045023	ZFP36/ZFP36L2/PABPC1/ZFP36L1/AGO2	5
GO:1902170	cellular response to reactive nitrogen species	5/2053	18/18722	0.0399651553954219	0.123337852045023	STAT6/CCNA2/HNRNPD/CDK2/MTR	5
GO:0006221	pyrimidine nucleotide biosynthetic process	7/2053	30/18722	0.04002313298861	0.123337852045023	DUT/UPP1/TYMS/DTYMK/UMPS/NME4/NME1	7
GO:0044030	regulation of DNA methylation	7/2053	30/18722	0.04002313298861	0.123337852045023	SPI1/PARP1/BRCA1/KDM1B/MIS18A/MBD2/MBD3	7
GO:0060674	placenta blood vessel development	7/2053	30/18722	0.04002313298861	0.123337852045023	SPINT1/JUNB/SOCS3/VASH1/NR2F2/NOTCH2/ITGB8	7
GO:0140058	neuron projection arborization	7/2053	30/18722	0.04002313298861	0.123337852045023	PHACTR1/LRRK2/LRP2/TPBG/NRP1/PAK6/PTN	7
GO:1903579	negative regulation of ATP metabolic process	7/2053	30/18722	0.04002313298861	0.123337852045023	TSPO/FBP1/PARP1/DDIT4/RHOA/STAT3/FIS1	7
GO:0003206	cardiac chamber morphogenesis	20/2053	121/18722	0.0400912958057559	0.12335783324848	TGFB1/MEF2C/LRP2/DSP/NRP2/BMP7/ENG/NOTCH1/ADAMTS1/NRP1/ISL1/NOTCH2/SOX4/GATA3/FHL2/FKBP1A/FOXC1/TGFBR3/TBX3/ADGRG6	20
GO:0038127	ERBB signaling pathway	20/2053	121/18722	0.0400912958057559	0.12335783324848	NCF1/TGFB1/PLAUR/EFEMP1/EGFR/IFI6/PTK2B/RHBDF2/CCDC88A/HBEGF/GRB2/RASSF2/DGKD/BCAR1/MVP/GAB1/VPS25/PTPN3/PTK2/RPS6KA5	20
GO:0043244	regulation of protein-containing complex disassembly	20/2053	121/18722	0.0400912958057559	0.12335783324848	PLEK/CAPG/TNF/IRAK3/DSTN/RDX/CIB1/TPX2/CKAP2/TWF2/SCIN/MID1IP1/SPTBN1/EPS8/ARHGEF2/IGF1R/BNIP3/LIMA1/INSR/TRIOBP	20
GO:0045727	positive regulation of translation	22/2053	136/18722	0.0401768465994213	0.123557703534868	VIM/TNF/PTAFR/PRKDC/PABPC1/RPL5/SERP1/NPM1/PTK2B/C1QBP/UQCC2/RHOA/SOX4/HNRNPD/UPF3A/RPS9/CDK4/EIF2AK4/PPP1R15A/AGO2/RPS4X/EIF4G1	22
GO:0046636	negative regulation of alpha-beta T cell activation	9/2053	43/18722	0.0407869050724645	0.125312199975667	LGALS9/LILRB1/CD300A/HMGB1/TNFRSF14/RUNX1/BCL6/RUNX3/GLI3	9
GO:0009260	ribonucleotide biosynthetic process	28/2053	182/18722	0.0407955545863149	0.125312199975667	TMSB4X/TGFB1/UPP1/PARP1/SLC26A2/MPC2/ACSS1/TECR/TREM2/PDK4/PAICS/PPT1/ALDOA/SLC25A1/UMPS/STAT3/ACSL4/GMPS/PDHA1/STOML2/NME4/ADK/IMPDH2/AMPD3/VCP/NME1/PPAT/PRKAG2	28
GO:0002438	acute inflammatory response to antigenic stimulus	6/2053	24/18722	0.0410188601253684	0.125312199975667	HLA-E/C3/BTK/ICAM1/GATA3/PARK7	6
GO:0002922	positive regulation of humoral immune response	6/2053	24/18722	0.0410188601253684	0.125312199975667	PTPRC/TNF/IL1B/C3/TREM2/PHB	6
GO:0007035	vacuolar acidification	6/2053	24/18722	0.0410188601253684	0.125312199975667	SLC11A1/GRN/PPT1/DMXL2/TCIRG1/ATP6V0E1	6
GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	6/2053	24/18722	0.0410188601253684	0.125312199975667	VEGFA/KLF2/CEBPB/NOTCH1/HSPA5/ATF3	6
GO:0036010	protein localization to endosome	6/2053	24/18722	0.0410188601253684	0.125312199975667	MSN/SORL1/RDX/NRP1/DTX3L/EZR	6
GO:0038095	Fc-epsilon receptor signaling pathway	6/2053	24/18722	0.0410188601253684	0.125312199975667	FCER1G/LYN/BTK/SYK/VAV1/VAV3	6
GO:0050855	regulation of B cell receptor signaling pathway	6/2053	24/18722	0.0410188601253684	0.125312199975667	LYN/CD300A/NFAM1/SLC39A10/CMTM3/PRKCB	6
GO:0072010	glomerular epithelium development	6/2053	24/18722	0.0410188601253684	0.125312199975667	PECAM1/CD24/NOTCH2/FOXC1/BASP1/ASXL1	6
GO:1903428	positive regulation of reactive oxygen species biosynthetic process	6/2053	24/18722	0.0410188601253684	0.125312199975667	CYBA/SOD2/TLR4/CD36/TLR6/PARK7	6
GO:2000310	regulation of NMDA receptor activity	6/2053	24/18722	0.0410188601253684	0.125312199975667	MEF2C/APP/CCR2/IFNGR2/PTK2B/CAPN1	6
GO:2000679	positive regulation of transcription regulatory region DNA binding	6/2053	24/18722	0.0410188601253684	0.125312199975667	TGFB1/KLF4/PARP1/GATA3/PARK7/FOXC1	6
GO:0008645	hexose transmembrane transport	19/2053	114/18722	0.041426472816828	0.126364431571412	SLC2A3/TNF/IL1B/SLC2A1/C3/MEF2A/HK2/PRKCB/SLC2A6/FABP5/RAP1A/ASPSCR1/RHOQ/YES1/INSR/PEA15/MAPK14/PRKAG2/GPC3	19
GO:0046660	female sex differentiation	19/2053	114/18722	0.041426472816828	0.126364431571412	RETN/VEGFA/LRP2/CEBPB/LHFPL2/ARRB2/SOD1/NR2F2/HSPA5/ICAM1/UBB/ADAMTS1/BRCA2/IDH1/ARID5B/FOXC1/TBX3/PLEKHA1/FANCA	19
GO:1903008	organelle disassembly	19/2053	114/18722	0.041426472816828	0.126364431571412	TSPO/PLK3/CDK1/SLC25A5/VRK1/HK2/BNIP3L/PHB2/SLC25A4/VDAC1/VPS13C/FIS1/PARK7/BNIP3/DENR/VCP/GABARAP/HUWE1/WIPI2	19
GO:0019318	hexose metabolic process	35/2053	237/18722	0.0416623593185856	0.12701938816642	HMGB1/FBP1/PHLDA2/TNF/SDS/PGP/SERP1/HK3/KCNQ1/PDK4/OAS1/HK2/SLC35B4/PMAIP1/AKR1B1/ALDOA/DCXR/DDB1/SLC25A1/FUCA1/FABP5/CHST15/LRP5/FUOM/FUT8/PDHA1/BAD/GAA/MIDN/C1QTNF1/LCMT1/ATF3/INSR/MAPK14/GAPDH	35
GO:0009142	nucleoside triphosphate biosynthetic process	15/2053	85/18722	0.042333662213016	0.129000494300709	TMSB4X/TGFB1/TYMS/PARP1/TREM2/DTYMK/ALDOA/STAT3/STOML2/NME4/ADK/IMPDH2/VCP/NME1/PRKAG2	15
GO:0045814	negative regulation of gene expression, epigenetic	10/2053	50/18722	0.0424517157348016	0.129228967229228	SPI1/HELLS/DNMT1/EZH2/TPR/POLE3/TRIM28/MBD2/MBD3/SMARCA5	10
GO:0060688	regulation of morphogenesis of a branching structure	10/2053	50/18722	0.0424517157348016	0.129228967229228	LRRK2/VEGFA/TNF/MAGED1/BMP7/PHB2/TACSTD2/LGR4/MDK/PDGFA	10
GO:0006949	syncytium formation	11/2053	57/18722	0.0433228083526835	0.13174700968885	TYROBP/CD53/CD9/PLEKHO1/CXCL10/CAMK1/ERVW-1/TREM2/ERVH48-1/ERCC1/MAPK14	11
GO:0061005	cell differentiation involved in kidney development	11/2053	57/18722	0.0433228083526835	0.13174700968885	MEF2C/STAT1/CD24/NOTCH1/NOTCH2/GATA3/LGR4/YAP1/GLI3/BASP1/ASXL1	11
GO:1903051	negative regulation of proteolysis involved in cellular protein catabolic process	12/2053	64/18722	0.0436124052010162	0.132560502130748	RPS7/HSP90AB1/RPL5/RPL23/PBK/SMARCC1/SDCBP/EFNA1/USP14/SVIP/PARK7/ALAD	12
GO:0051259	protein complex oligomerization	35/2053	238/18722	0.0438834846208624	0.133316915303886	HLA-DRB1/CD74/ISG15/SAMHD1/PYCARD/KCTD12/B2M/GBP5/SOD2/ALOX5AP/RRM1/VASP/FUS/LRRC8C/RRM2/TK1/ALDOA/RNF213/CHP1/TRPM2/NLRP1/BLM/SLC1A5/STOML2/SLC9A1/ECT2/RBMX/SHMT1/POLQ/STK4/KRT10/SIGMAR1/KCTD1/HOMER1/ALAD	35
GO:0006626	protein targeting to mitochondrion	17/2053	100/18722	0.044002690845759	0.133355373252448	TSPO/RAC2/LRRK2/LMAN1/HSPD1/HSP90AA1/BNIP3L/TIMM13/TOMM40/PDCD5/TOMM34/DNAJC19/SAE1/FIS1/PMPCB/HUWE1/NDUFA13	17
GO:0046545	development of primary female sexual characteristics	17/2053	100/18722	0.044002690845759	0.133355373252448	RETN/VEGFA/CEBPB/LHFPL2/ARRB2/SOD1/NR2F2/HSPA5/ICAM1/UBB/ADAMTS1/BRCA2/IDH1/ARID5B/FOXC1/PLEKHA1/FANCA	17
GO:0110020	regulation of actomyosin structure organization	17/2053	100/18722	0.044002690845759	0.133355373252448	WAS/GPR65/STMN1/PTGER4/MET/CCDC88A/TACSTD2/S100A10/NRP1/RHOA/RGCC/TJP1/FERMT2/WASF2/PFN1/SLC9A1/ECT2	17
GO:0033120	positive regulation of RNA splicing	8/2053	37/18722	0.04402949906885	0.133355373252448	HSPA8/PRDX6/NCL/HSPA1A/RBMX/TRA2B/SNRNP70/PRPF19	8
GO:0042401	cellular biogenic amine biosynthetic process	8/2053	37/18722	0.04402949906885	0.133355373252448	OAZ1/NR4A2/SAT1/SMS/GATA3/SRM/PARK7/GCH1	8
GO:0043368	positive T cell selection	8/2053	37/18722	0.04402949906885	0.133355373252448	PTPRC/CD74/CTSL/DOCK2/STAT6/IL6R/SPN/STAT3	8
GO:0007589	body fluid secretion	16/2053	93/18722	0.0451967521969689	0.136821651453993	CYBA/OAS2/EGFR/VEGFA/CCND1/STAT5A/HK2/SLC29A1/CDO1/UMPS/VDR/KCNN4/NCOR2/MTX1/NME1/PPAT	16
GO:0001833	inner cell mass cell proliferation	4/2053	13/18722	0.0458475814456186	0.137063023753718	CHEK1/BRCA2/SBDS/NCAPG2	4
GO:0002430	complement receptor mediated signaling pathway	4/2053	13/18722	0.0458475814456186	0.137063023753718	FPR1/C5AR1/FPR3/C3AR1	4
GO:0009650	UV protection	4/2053	13/18722	0.0458475814456186	0.137063023753718	GPX1/FEN1/SCARA3/ERCC1	4
GO:0010917	negative regulation of mitochondrial membrane potential	4/2053	13/18722	0.0458475814456186	0.137063023753718	BNIP3L/PMAIP1/HEBP2/BNIP3	4
GO:0033262	regulation of nuclear cell cycle DNA replication	4/2053	13/18722	0.0458475814456186	0.137063023753718	BCL6/CDT1/DBF4/TIPIN	4
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	4/2053	13/18722	0.0458475814456186	0.137063023753718	LYN/TNFAIP3/LILRA2/TREM2	4
GO:0034982	mitochondrial protein processing	4/2053	13/18722	0.0458475814456186	0.137063023753718	LRRK2/STOML2/AFG3L2/PMPCB	4
GO:0036462	TRAIL-activated apoptotic signaling pathway	4/2053	13/18722	0.0458475814456186	0.137063023753718	SPI1/TIMP3/PARK7/ATF3	4
GO:0042492	gamma-delta T cell differentiation	4/2053	13/18722	0.0458475814456186	0.137063023753718	PTPRC/NCKAP1L/SYK/SOX4	4
GO:0042538	hyperosmotic salinity response	4/2053	13/18722	0.0458475814456186	0.137063023753718	AKR1B1/XRCC5/XRCC6/EFHD1	4
GO:0043970	histone H3-K9 acetylation	4/2053	13/18722	0.0458475814456186	0.137063023753718	BRCA1/CHEK1/GATA3/ZNF451	4
GO:0044794	positive regulation by host of viral process	4/2053	13/18722	0.0458475814456186	0.137063023753718	NUCKS1/PPIB/HSPA8/CFL1	4
GO:0046689	response to mercury ion	4/2053	13/18722	0.0458475814456186	0.137063023753718	AQP9/BSG/PARK7/ALAD	4
GO:0048012	hepatocyte growth factor receptor signaling pathway	4/2053	13/18722	0.0458475814456186	0.137063023753718	STMN1/MET/NRP1/BCAR1	4
GO:0048711	positive regulation of astrocyte differentiation	4/2053	13/18722	0.0458475814456186	0.137063023753718	NOTCH1/IL6ST/ID2/PRPF19	4
GO:0060100	positive regulation of phagocytosis, engulfment	4/2053	13/18722	0.0458475814456186	0.137063023753718	NCKAP1L/CD36/C3/TREM2	4
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	4/2053	13/18722	0.0458475814456186	0.137063023753718	ZFP36/PABPC1/BTG2/AGO2	4
GO:0060670	branching involved in labyrinthine layer morphogenesis	4/2053	13/18722	0.0458475814456186	0.137063023753718	SPINT1/SPINT2/SOCS3/GRB2	4
GO:0072672	neutrophil extravasation	4/2053	13/18722	0.0458475814456186	0.137063023753718	PECAM1/JAML/ADAM8/MDK	4
GO:0110096	cellular response to aldehyde	4/2053	13/18722	0.0458475814456186	0.137063023753718	ADH5/AKR1B1/ALDH1A1/PARK7	4
GO:1900272	negative regulation of long-term synaptic potentiation	4/2053	13/18722	0.0458475814456186	0.137063023753718	TYROBP/APP/CX3CR1/PTN	4
GO:1902947	regulation of tau-protein kinase activity	4/2053	13/18722	0.0458475814456186	0.137063023753718	C5AR1/SORL1/HSP90AA1/HSP90AB1	4
GO:1903651	positive regulation of cytoplasmic transport	4/2053	13/18722	0.0458475814456186	0.137063023753718	MSN/SORL1/RDX/EZR	4
GO:1903977	positive regulation of glial cell migration	4/2053	13/18722	0.0458475814456186	0.137063023753718	CCL3/CCR2/TREM2/CX3CR1	4
GO:1905155	positive regulation of membrane invagination	4/2053	13/18722	0.0458475814456186	0.137063023753718	NCKAP1L/CD36/C3/TREM2	4
GO:0034440	lipid oxidation	18/2053	108/18722	0.0462347895540106	0.138024688712328	ALOX5/SLC27A2/ECI1/ECHS1/PLA2G7/PDK4/ADH5/ACADVL/ECHDC2/ETFB/HADH/ETFA/ACAT2/ECI2/SLC25A17/ECH1/MAPK14/PRKAG2	18
GO:0006140	regulation of nucleotide metabolic process	15/2053	86/18722	0.0462842789482008	0.138024688712328	TMSB4X/FBP1/PARP1/APP/TREM2/CDA/PDK4/P2RX7/DDIT4/SLC2A6/STAT3/ARL2/INSR/VCP/PRKAG2	15
GO:0035023	regulation of Rho protein signal transduction	15/2053	86/18722	0.0462842789482008	0.138024688712328	ARHGDIB/GPR65/STMN1/LPAR6/ADGRG1/MET/ITGB1/BCL6/KANK1/NRP1/NET1/EPS8/ARHGEF2/EPS8L2/CCDC125	15
GO:0048864	stem cell development	15/2053	86/18722	0.0462842789482008	0.138024688712328	PTPRC/FN1/NRP2/BMP7/LAMA5/SEMA4A/SEMA6A/MSI2/NRP1/ISL1/FOLR1/SEMA6D/TCOF1/CORO1C/FOXC1	15
GO:0060761	negative regulation of response to cytokine stimulus	15/2053	86/18722	0.0462842789482008	0.138024688712328	PTPRC/ISG15/SAMHD1/KLF4/IRAK3/GSTP1/IL1RN/CARD16/TREM2/SH2B3/OAS1/NLRC5/STAT2/PARP14/PPARG	15
GO:0003205	cardiac chamber development	25/2053	161/18722	0.0464397441349411	0.138321776061582	TGFB1/MEF2C/LRP2/DSP/NRP2/BMP7/ENG/NOTCH1/LMO4/ADAMTS1/ADAMTS6/GJA5/NRP1/ISL1/NOTCH2/SOX4/GATA3/CNTRL/FHL2/FKBP1A/LUZP1/FOXC1/TGFBR3/TBX3/ADGRG6	25
GO:0002066	columnar/cuboidal epithelial cell development	9/2053	44/18722	0.0464761167566917	0.138321776061582	TYMS/RARA/RHEB/IL6ST/YAP1/CDK6/KLF5/BAD/CDKN1A	9
GO:0021762	substantia nigra development	9/2053	44/18722	0.0464761167566917	0.138321776061582	ACTB/MBP/HSPA5/RHOA/CALM2/CCDC14/YWHAE/GNB4/BASP1	9
GO:1903573	negative regulation of response to endoplasmic reticulum stress	9/2053	44/18722	0.0464761167566917	0.138321776061582	LRRK2/ALOX5/HSPA5/USP14/SVIP/PARK7/HSPA1A/PPP1R15A/DNAJB9	9
GO:0006338	chromatin remodeling	37/2053	255/18722	0.0465009867316971	0.138327179172128	NASP/ACTB/HMGB2/HELLS/DNAJC9/CENPW/SUPT16H/NPM1/ASF1B/SET/NAP1L1/RBBP4/MCM2/HAT1/CBX3/BAZ1B/ITGB3BP/SMARCA1/HDAC2/HMGA1/SMARCC1/GATA3/CHAF1A/BAZ2B/POLE3/SMARCA2/NUDT5/MIS18A/RERE/RNF8/NAP1L4/KDM6B/ACTL6A/MBD2/ACTR6/MBD3/SMARCA5	37
GO:0030201	heparan sulfate proteoglycan metabolic process	7/2053	31/18722	0.046979865754871	0.138925182123818	HPSE/EXTL2/SULF2/DSE/GPC1/B3GAT3/HS6ST2	7
GO:0031063	regulation of histone deacetylation	7/2053	31/18722	0.046979865754871	0.138925182123818	LRRK2/VEGFA/BCL6/CAMK2D/JDP2/ING2/NCAPG2	7
GO:0033238	regulation of cellular amine metabolic process	7/2053	31/18722	0.046979865754871	0.138925182123818	ITGB2/SLC7A7/ITGAM/NR4A2/COMT/PNKD/PARK7	7
GO:0034656	nucleobase-containing small molecule catabolic process	7/2053	31/18722	0.046979865754871	0.138925182123818	APOBEC3A/UPP1/DPYD/CDA/APOBEC3G/APOBEC3C/PNP	7
GO:0035510	DNA dealkylation	7/2053	31/18722	0.046979865754871	0.138925182123818	APOBEC3A/APOBEC3G/APOBEC3C/GATA3/APEX1/ASCC3/TRIM28	7
GO:0036474	cell death in response to hydrogen peroxide	7/2053	31/18722	0.046979865754871	0.138925182123818	LRRK2/MET/PAWR/TXN/PARK7/TRAP1/SIGMAR1	7
GO:0036475	neuron death in response to oxidative stress	7/2053	31/18722	0.046979865754871	0.138925182123818	TLR4/PARP1/TLR6/TREM2/MCL1/TRPM2/PARK7	7
GO:0048384	retinoic acid receptor signaling pathway	7/2053	31/18722	0.046979865754871	0.138925182123818	KLF2/RARA/CALR/EZH2/ASXL1/ACTN4/PPARG	7
GO:0071168	protein localization to chromatin	7/2053	31/18722	0.046979865754871	0.138925182123818	SPI1/EZH2/MSH2/CDCA5/RAD21/ESCO2/VCP	7
GO:0071711	basement membrane organization	7/2053	31/18722	0.046979865754871	0.138925182123818	CTSS/SPINT2/LAMB1/DAG1/ITGB1/FERMT1/COL4A1	7
GO:0090162	establishment of epithelial cell polarity	7/2053	31/18722	0.046979865754871	0.138925182123818	MSN/FAT1/FERMT1/RHOA/FRMD4A/PARD3/CYTH1	7
GO:0090183	regulation of kidney development	7/2053	31/18722	0.046979865754871	0.138925182123818	VEGFA/STAT1/MAGED1/TACSTD2/GATA3/LGR4/BASP1	7
GO:0000245	spliceosomal complex assembly	14/2053	79/18722	0.0472190476648516	0.139494970944909	CELF2/SNRPG/SNRPD1/PSIP1/SNRPE/SF1/SRSF10/SRPK1/DDX1/USP39/SF3A3/LUC7L3/SNRPD2/PRPF19	14
GO:0032272	negative regulation of protein polymerization	14/2053	79/18722	0.0472190476648516	0.139494970944909	TMSB4X/CAPG/TMSB10/STMN1/MYADM/KANK1/RDX/KANK4/TWF2/SCIN/SPTBN1/PFN1/EPS8/TRIOBP	14
GO:0009152	purine ribonucleotide biosynthetic process	26/2053	169/18722	0.0472976813070493	0.139658507796405	TMSB4X/TGFB1/PARP1/SLC26A2/MPC2/ACSS1/TECR/TREM2/PDK4/PAICS/PPT1/ALDOA/SLC25A1/STAT3/ACSL4/GMPS/PDHA1/STOML2/NME4/ADK/IMPDH2/AMPD3/VCP/NME1/PPAT/PRKAG2	26
GO:0032873	negative regulation of stress-activated MAPK cascade	10/2053	51/18722	0.0478193961614171	0.140990848633171	DUSP1/GSTP1/PPIA/TREM2/PBK/MARVELD3/SIRPA/EZR/DLG1/FOXM1	10
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	10/2053	51/18722	0.0478193961614171	0.140990848633171	PYCARD/LILRB4/TNFAIP3/GSTP1/STAT1/TREM2/NLRP12/RHOA/USP10/TLE1	10
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	10/2053	51/18722	0.0478193961614171	0.140990848633171	DUSP1/GSTP1/PPIA/TREM2/PBK/MARVELD3/SIRPA/EZR/DLG1/FOXM1	10
GO:1901880	negative regulation of protein depolymerization	13/2053	72/18722	0.0479394283607329	0.141275329157366	CAPG/RDX/CIB1/TPX2/CKAP2/TWF2/SCIN/MID1IP1/SPTBN1/EPS8/ARHGEF2/LIMA1/TRIOBP	13
GO:0015749	monosaccharide transmembrane transport	19/2053	116/18722	0.0482028292480956	0.141981824000282	SLC2A3/TNF/IL1B/SLC2A1/C3/MEF2A/HK2/PRKCB/SLC2A6/FABP5/RAP1A/ASPSCR1/RHOQ/YES1/INSR/PEA15/MAPK14/PRKAG2/GPC3	19
GO:0010574	regulation of vascular endothelial growth factor production	11/2053	58/18722	0.0483746399325956	0.142278352742928	TGFB1/C5AR1/C3AR1/IL1B/CCR2/C3/HPSE/BRCA1/SULF2/ISL1/IL6ST	11
GO:0032387	negative regulation of intracellular transport	11/2053	58/18722	0.0483746399325956	0.142278352742928	LRRK2/LMAN1/CD36/FERMT1/CHP1/BARD1/TXN/TPR/SVIP/SP100/PARK7	11
GO:2000649	regulation of sodium ion transmembrane transporter activity	11/2053	58/18722	0.0483746399325956	0.142278352742928	FXYD5/FXYD3/GLRX/KCNQ1/CAMK2D/CHP1/ANK3/SLC9A1/DMD/PTPN3/ACTN4	11
GO:0090287	regulation of cellular response to growth factor stimulus	43/2053	304/18722	0.0486539176708227	0.143029645284143	ZEB2/TGFB1/SORL1/PEG10/SKIL/FBN2/ITGA5/FBN1/LRP2/IL1B/HSP90AB1/NREP/ENG/NOTCH1/HHEX/CRIM1/HSPA5/FSTL1/LDLRAD4/SEMA6A/PRKCB/CDKN1C/FERMT1/SULF2/LTBP1/NOTCH2/GATA3/EPN2/FOLR1/UBE2D1/MYO1C/SDCBP/CD63/HSPA1A/GPC1/FKBP1A/ING2/ZNF451/TGFBR3/EID2/CTDSPL2/PPARG/GPC3	43
GO:0140013	meiotic nuclear division	28/2053	185/18722	0.0486943447716975	0.143078388163656	TOP2A/SMC2/RAD51AP1/CALR/RAD51/CCNE1/ASPM/SMC4/UBB/RAD51C/CKS2/ACTR2/FBXO5/RAD21/CCNE2/NUF2/MND1/BRCA2/FANCD2/RAD50/PSMC3IP/ACTR3/TTK/TOP2B/ING2/BUB1B/FIGNL1/FANCA	28
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	37/2053	256/18722	0.0488290766171004	0.143404042928342	ZEB2/TGFB1/SORL1/PEG10/SKIL/FBN2/JAK2/FBN1/LRP2/PARP1/HSP90AB1/BMP7/NREP/ENG/NOTCH1/CRIM1/HSPA5/FSTL1/LDLRAD4/CDKN1C/FERMT1/LTBP1/RBPMS/NOTCH2/FOLR1/UBE2D1/SDCBP/TTK/HSPA1A/FKBP1A/ING2/ZNF451/TGFBR3/EID2/CTDSPL2/PPARG/GPC3	37
GO:0009147	pyrimidine nucleoside triphosphate metabolic process	6/2053	25/18722	0.0491390869024835	0.143751595034081	DUT/TYMS/DTYMK/NME4/DCTPP1/NME1	6
GO:0010996	response to auditory stimulus	6/2053	25/18722	0.0491390869024835	0.143751595034081	CXCL10/CNTNAP2/USP53/MDK/PTN/SLC1A3	6
GO:0033119	negative regulation of RNA splicing	6/2053	25/18722	0.0491390869024835	0.143751595034081	NPM1/C1QBP/SRSF10/SRSF7/RBMX/SRSF4	6
GO:0060706	cell differentiation involved in embryonic placenta development	6/2053	25/18722	0.0491390869024835	0.143751595034081	SPINT2/SOCS3/NR2F2/KRT8/STK4/E2F7	6
GO:0070199	establishment of protein localization to chromosome	6/2053	25/18722	0.0491390869024835	0.143751595034081	TCP1/CCT6A/BRCA2/CCT2/CCT4/CCT8	6
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	6/2053	25/18722	0.0491390869024835	0.143751595034081	TNFAIP3/TLR4/NFKBIA/SLC15A3/BIRC3/HSPA1A	6
GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA	6/2053	25/18722	0.0491390869024835	0.143751595034081	TGFB1/EGFR/TNF/LIN28B/STAT3/NCOR2	6
GO:1903901	negative regulation of viral life cycle	6/2053	25/18722	0.0491390869024835	0.143751595034081	FCN1/BST2/IFITM2/IFITM3/CIITA/PPIA	6
GO:0034250	positive regulation of cellular amide metabolic process	25/2053	162/18722	0.0494185481695985	0.144026812366033	VIM/TNF/PTAFR/PRKDC/PABPC1/RPL5/SERP1/NPM1/PTK2B/C1QBP/UQCC2/RHOA/SOX4/HNRNPD/UPF3A/RPS9/CDK4/EFNA1/EIF2AK4/PPP1R15A/AGO2/IFNGR1/PICALM/RPS4X/EIF4G1	25
GO:0006144	purine nucleobase metabolic process	5/2053	19/18722	0.0494972145164601	0.144026812366033	DPYD/PAICS/GMPS/SHMT1/PPAT	5
GO:0010544	negative regulation of platelet activation	5/2053	19/18722	0.0494972145164601	0.144026812366033	CD9/SH2B3/C1QTNF1/UBASH3B/PDGFA	5
GO:0010759	positive regulation of macrophage chemotaxis	5/2053	19/18722	0.0494972145164601	0.144026812366033	CSF1R/C5AR1/C3AR1/MDK/PTK2	5
GO:0010829	negative regulation of glucose transmembrane transport	5/2053	19/18722	0.0494972145164601	0.144026812366033	TNF/IL1B/PRKCB/FABP5/PEA15	5
GO:0030220	platelet formation	5/2053	19/18722	0.0494972145164601	0.144026812366033	MEF2C/PRKDC/PTPN6/NBEAL2/CIB1	5
GO:0031065	positive regulation of histone deacetylation	5/2053	19/18722	0.0494972145164601	0.144026812366033	LRRK2/VEGFA/BCL6/JDP2/ING2	5
GO:0036344	platelet morphogenesis	5/2053	19/18722	0.0494972145164601	0.144026812366033	MEF2C/PRKDC/PTPN6/NBEAL2/CIB1	5
GO:0045780	positive regulation of bone resorption	5/2053	19/18722	0.0494972145164601	0.144026812366033	EGFR/SPP1/SYK/ADAM8/TFRC	5
GO:0045947	negative regulation of translational initiation	5/2053	19/18722	0.0494972145164601	0.144026812366033	RPL13A/TPR/EIF2AK4/EIF2AK1/AGO2	5
GO:0061760	antifungal innate immune response	5/2053	19/18722	0.0494972145164601	0.144026812366033	SPI1/CLEC7A/CLEC4E/CX3CR1/USP15	5
GO:0032414	positive regulation of ion transmembrane transporter activity	18/2053	109/18722	0.0499321131522638	0.145221851145702	CTSS/TMSB4X/TCAF1/PTAFR/CCR2/GLRX/IFNGR2/TREM2/VMP1/KCNE3/CHP1/CALM2/ANK3/SLC9A1/DMD/AKAP9/ACTN4/COX17	18
GO:0051262	protein tetramerization	15/2053	87/18722	0.0504870323891747	0.146644494028648	HLA-DRB1/SAMHD1/B2M/GBP5/SOD2/RRM1/VASP/RRM2/TK1/ALDOA/TRPM2/SHMT1/STK4/KRT10/HOMER1	15
GO:1901879	regulation of protein depolymerization	15/2053	87/18722	0.0504870323891747	0.146644494028648	PLEK/CAPG/DSTN/RDX/CIB1/TPX2/CKAP2/TWF2/SCIN/MID1IP1/SPTBN1/EPS8/ARHGEF2/LIMA1/TRIOBP	15
GO:0007007	inner mitochondrial membrane organization	8/2053	38/18722	0.0506167911888882	0.146644494028648	TIMM13/IMMT/CHCHD10/AFG3L2/MTX1/MTX2/HSPA9/NDUFA13	8
GO:0009309	amine biosynthetic process	8/2053	38/18722	0.0506167911888882	0.146644494028648	OAZ1/NR4A2/SAT1/SMS/GATA3/SRM/PARK7/GCH1	8
GO:0010742	macrophage derived foam cell differentiation	8/2053	38/18722	0.0506167911888882	0.146644494028648	TGFB1/MSR1/CD36/STAT1/NFKBIA/ITGAV/IL18/PPARG	8
GO:0048246	macrophage chemotaxis	8/2053	38/18722	0.0506167911888882	0.146644494028648	CCL3/CSF1R/C5AR1/C3AR1/LGALS3/PTK2B/MDK/PTK2	8
GO:0071398	cellular response to fatty acid	8/2053	38/18722	0.0506167911888882	0.146644494028648	PTAFR/PDK4/CDK4/ASS1/ID3/XRCC5/NME1/E2F1	8
GO:0090077	foam cell differentiation	8/2053	38/18722	0.0506167911888882	0.146644494028648	TGFB1/MSR1/CD36/STAT1/NFKBIA/ITGAV/IL18/PPARG	8
GO:0015711	organic anion transport	49/2053	354/18722	0.051621185056625	0.149431596894603	SLC11A1/SLC2A3/SLC7A7/SLC16A3/PSAP/LRP2/AQP9/IL1B/CD36/SLC2A1/SLC38A1/SLC26A2/SYK/MPC2/SLC25A5/ITGB1/LRRC8C/SLC29A1/GJA1/SLC2A6/SLC35B4/SLC6A6/SLC22A11/SLC25A1/SLC1A5/SLC16A12/SFXN3/SLC25A4/SLC16A1/FOLR1/SLC19A1/SFXN1/MGST1/CYB5R4/RGS2/SLC52A1/SLC13A3/BEST1/CYB5R1/PTGES/SLC7A6/SLC38A9/SLC25A17/MPC1/SLC25A6/SLC38A6/SLC3A2/SLC1A3/SLC10A3	49
GO:1903364	positive regulation of cellular protein catabolic process	24/2053	155/18722	0.0516286167270852	0.149431596894603	LAPTM5/MSN/LRRK2/LRP2/TNFAIP3/PLK3/HSP90AA1/TREM2/PTK2B/HAMP/PSMC3/TRIB1/RDX/PSMC1/BAG2/PSMC2/MAGEF1/TMTC3/EZR/HSPA1A/VCP/PLK2/GABARAP/PTK2	24
GO:0071229	cellular response to acid chemical	14/2053	80/18722	0.0516955007837789	0.149553039875927	CYBB/CYBA/VEGFA/KLF2/TNF/CEBPB/DNMT1/LAMTOR4/HNRNPD/GCLM/ASS1/COL4A1/IPO5/SLC38A9	14
GO:0071322	cellular response to carbohydrate stimulus	25/2053	163/18722	0.0525333131717669	0.151688682149004	HLA-DRB1/LGALS1/CYBA/CLEC7A/UCP2/COLEC12/SERPINF1/MPC2/ZFP36L1/TREM2/ICAM1/SLC29A1/PRKCB/HMGN3/KLF7/SOX4/GCLM/LRP5/FIS1/PHPT1/BAD/IGF1R/TRA2B/NME1/CCDC186	25
GO:0072503	cellular divalent inorganic cation homeostasis	65/2053	486/18722	0.0525525182424924	0.151688682149004	S100A8/PTPRC/CXCR4/CD52/CORO1A/CCL3/SLC11A1/CYBA/FPR1/C5AR1/LYN/FPR3/SLC8A1/C3AR1/GPR65/HMGB1/JAK2/LPAR6/CCR1/HSP90B1/CD36/APP/CCR2/PTGER4/CXCL10/CD24/S1PR4/TGM2/MT1X/PTPN6/S100A9/CCRL2/CALR/CCDC47/ATP2B1/PTK2B/TRPV2/P2RX7/GNA15/SLC39A10/CYSLTR1/PRKCB/GJA1/CX3CR1/CAMK2D/TRPM2/CALM2/MT2A/MCOLN3/VDR/ITGAV/IMMT/STOML2/AFG3L2/SLC39A7/FIS1/YWHAE/MCUR1/DMD/TCIRG1/BNIP3/FKBP1A/C1QTNF1/UBASH3B/HEXB	65
GO:0003254	regulation of membrane depolarization	9/2053	45/18722	0.052668653542154	0.151688682149004	TSPO/LRRK2/PARP1/IFI6/CAMK2D/GJA5/GCLM/ANK3/PTPN3	9
GO:0006110	regulation of glycolytic process	9/2053	45/18722	0.052668653542154	0.151688682149004	FBP1/APP/P2RX7/DDIT4/SLC2A6/STAT3/ARL2/INSR/PRKAG2	9
GO:0060421	positive regulation of heart growth	9/2053	45/18722	0.052668653542154	0.151688682149004	MEF2C/CDK1/NOTCH1/HAMP/YAP1/PARP2/TGFBR3/BASP1/MAPK14	9
GO:0071364	cellular response to epidermal growth factor stimulus	9/2053	45/18722	0.052668653542154	0.151688682149004	ZFP36/ZFP36L2/EGFR/MCM7/GSTP1/ZFP36L1/ID1/NCL/FOXC1	9
GO:2000273	positive regulation of signaling receptor activity	9/2053	45/18722	0.052668653542154	0.151688682149004	NCF1/JAK2/CCR2/IFNGR2/ITGB1/HBEGF/NRP1/HDAC2/PARK7	9
GO:0030900	forebrain development	52/2053	379/18722	0.0526856814799284	0.151688682149004	TYROBP/CXCR4/BCL2A1/FLNA/PHACTR1/B2M/SLC8A1/LRRK2/ITGAM/LRP2/CDH1/NR4A2/APP/RRM1/SLC2A1/ADGRG1/LAMB1/NRP2/RARA/C12orf57/NOTCH1/NR2F2/BTG2/ASPM/EZH2/UBB/UQCRQ/CNTNAP2/NRP1/ISL1/ZSWIM6/RHOA/GNG12/ATF5/CDK6/ANXA3/NRGN/TACC2/BAD/TOP2B/BNIP3/TRA2B/GLI3/ID2/NUMB/MDK/KDM6B/NME1/PTN/TBX3/E2F1/RAC3	52
GO:0035924	cellular response to vascular endothelial growth factor stimulus	13/2053	73/18722	0.0527118170467789	0.151688682149004	VEGFA/NRP2/NOTCH1/NR4A1/SEMA6A/FLT1/NRP1/SPHK1/MYO1C/CD63/GAB1/FOXC1/MAPK14	13
GO:0072088	nephron epithelium morphogenesis	13/2053	73/18722	0.0527118170467789	0.151688682149004	VEGFA/STAT1/MAGED1/LAMA5/TACSTD2/AHI1/GATA3/PBX1/LGR4/DLG1/GLI3/IRX2/GPC3	13
GO:0072089	stem cell proliferation	13/2053	73/18722	0.0527118170467789	0.151688682149004	PTPRC/FBLN1/HMGB2/RUNX1/ZFP36L1/RNF43/CCNE1/GJA1/FERMT1/YAP1/FERMT2/TBX3/ZNRF3	13
GO:0007044	cell-substrate junction assembly	16/2053	95/18722	0.0533318688107259	0.153325928540659	FN1/VEGFA/ITGA6/ITGB4/PTK2B/LAMC1/S100A10/LIMS1/NRP1/RHOA/FERMT2/SLC9A1/VCL/CORO1C/PTK2/TRIP6	16
GO:0008585	female gonad development	16/2053	95/18722	0.0533318688107259	0.153325928540659	RETN/VEGFA/CEBPB/ARRB2/SOD1/NR2F2/HSPA5/ICAM1/UBB/ADAMTS1/BRCA2/IDH1/ARID5B/FOXC1/PLEKHA1/FANCA	16
GO:0050918	positive chemotaxis	12/2053	66/18722	0.0534544764046871	0.153604817254848	CORO1A/CCL3/HMGB1/VEGFA/HMGB2/CXCL10/MET/GPNMB/LGALS3/IL16/CXCL8/NRP1	12
GO:0070585	protein localization to mitochondrion	20/2053	125/18722	0.0535670592725598	0.153854646067668	TSPO/ISG15/RAC2/LRRK2/LMAN1/HSPD1/HSP90AA1/HK2/BNIP3L/TIMM13/TOMM40/PDCD5/TOMM34/DNAJC19/SAE1/FIS1/NMT1/PMPCB/HUWE1/NDUFA13	20
GO:0072523	purine-containing compound catabolic process	10/2053	52/18722	0.053624098764667	0.153944781142585	SAMHD1/HINT1/DPYD/PDE4A/NUDT8/NUDT15/PNP/NUDT4/AMPD3/DNPH1	10
GO:0042593	glucose homeostasis	37/2053	258/18722	0.0537423763747652	0.15417767686101	HLA-DRB1/LGALS1/CYBA/UCP2/ALOX5/SERPINF1/MPC2/NUCKS1/TREM2/HK3/PDK4/ICAM1/OAS1/HK2/SLC29A1/FAM3B/HMGN3/KLF7/FABP5/STAT3/SOX4/SLC16A1/GCLM/RPS6/LRP5/CYB5R4/FIS1/ASPSCR1/PARK7/PHPT1/BAD/IGF1R/TRA2B/INSR/NME1/CCDC186/PPARG	37
GO:0006767	water-soluble vitamin metabolic process	11/2053	59/18722	0.0538110745820045	0.15417767686101	SLC2A3/SLC2A1/DHFR/FOLR1/SLC19A1/SLC52A1/SHMT1/MMAB/SLC19A3/MTR/CD320	11
GO:0030042	actin filament depolymerization	11/2053	59/18722	0.0538110745820045	0.15417767686101	PLEK/CAPG/DSTN/RDX/TWF2/SCIN/SPTBN1/EPS8/LIMA1/TRIOBP/CFL1	11
GO:0046324	regulation of glucose import	11/2053	59/18722	0.0538110745820045	0.15417767686101	TNF/MEF2A/HK2/RAP1A/ASPSCR1/RHOQ/INSR/PEA15/MAPK14/PRKAG2/GPC3	11
GO:0014812	muscle cell migration	18/2053	110/18722	0.0538337055039693	0.15417767686101	AIF1/SORL1/MEF2C/PLEKHO1/TLR4/GSTP1/DOCK4/S100A11/ADAMTS1/TRIB1/NRP1/RHOA/SEMA6D/NET1/FOXO4/APEX1/MDK/PDGFA	18
GO:0010039	response to iron ion	7/2053	32/18722	0.054661935892856	0.15580599304377	B2M/HMOX1/C1QA/HAMP/CCND1/TFAP2A/ALAD	7
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	7/2053	32/18722	0.054661935892856	0.15580599304377	ZEB2/HSP90AB1/CDKN1C/FERMT1/SDCBP/ING2/TGFBR3	7
GO:0033687	osteoblast proliferation	7/2053	32/18722	0.054661935892856	0.15580599304377	JUNB/HPSE/RHOA/ITGAV/LRP5/ATRAID/FIGNL1	7
GO:0035767	endothelial cell chemotaxis	7/2053	32/18722	0.054661935892856	0.15580599304377	TMSB4X/HMGB1/VEGFA/MET/NOTCH1/NR4A1/NRP1	7
GO:0042744	hydrogen peroxide catabolic process	7/2053	32/18722	0.054661935892856	0.15580599304377	GPX1/PRDX2/PRDX4/PRDX5/PRDX3/PRDX6/PRDX1	7
GO:0050685	positive regulation of mRNA processing	7/2053	32/18722	0.054661935892856	0.15580599304377	HSPA8/PRDX6/NCL/RBMX/TRA2B/SNRNP70/PRPF19	7
GO:0051497	negative regulation of stress fiber assembly	7/2053	32/18722	0.054661935892856	0.15580599304377	WAS/STMN1/MET/TACSTD2/TJP1/WASF2/PFN1	7
GO:0072337	modified amino acid transport	7/2053	32/18722	0.054661935892856	0.15580599304377	LRP2/GJA1/SLC16A12/FOLR1/SLC19A1/MGST1/SLC13A3	7
GO:1900745	positive regulation of p38MAPK cascade	7/2053	32/18722	0.054661935892856	0.15580599304377	NCF1/SPI1/VEGFA/IL1B/GADD45B/SPHK1/MAP3K4	7
GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	7/2053	32/18722	0.054661935892856	0.15580599304377	ZEB2/HSP90AB1/CDKN1C/FERMT1/SDCBP/ING2/TGFBR3	7
GO:0031110	regulation of microtubule polymerization or depolymerization	15/2053	88/18722	0.0549480147068836	0.156398523833635	STMN1/RPS3/MET/CLIP1/CIB1/TPX2/CKAP2/ARL2/MID1IP1/SKA2/ARHGEF2/HSPA1A/SKA3/AKAP9/DRG1	15
GO:0050829	defense response to Gram-negative bacterium	15/2053	88/18722	0.0549480147068836	0.156398523833635	LYZ/SLC11A1/PYCARD/CD4/TNFRSF14/CASP1/TLR4/TREM1/HMGB2/MPEG1/RNASE6/TREM2/IL6R/RPS19/DEFB1	15
GO:0070098	chemokine-mediated signaling pathway	15/2053	88/18722	0.0549480147068836	0.156398523833635	CCL3L3/CXCR4/CCL3/CCL4/CCR1/CCR2/CXCL10/CCRL2/TREM2/PTK2B/SH2B3/CX3CR1/CXCL8/CIB1/FOXC1	15
GO:0032869	cellular response to insulin stimulus	30/2053	203/18722	0.0554079253427872	0.157632789026422	SORL1/UCP2/PARP1/IL1B/GSTP1/STAT1/SOCS3/PRKDC/NUCKS1/ZFP36L1/ATP2B1/PDK4/PRKCB/KANK1/GNAI2/CCND3/SMARCC1/CDK4/MYO1C/GRB2/FOXO4/RHOQ/SLC9A1/BCAR1/IGF1R/GAB1/INSR/MYO5A/PPAT/PPARG	30
GO:0034219	carbohydrate transmembrane transport	19/2053	118/18722	0.0557345135324182	0.15848676833863	SLC2A3/TNF/IL1B/SLC2A1/C3/MEF2A/HK2/PRKCB/SLC2A6/FABP5/RAP1A/ASPSCR1/RHOQ/YES1/INSR/PEA15/MAPK14/PRKAG2/GPC3	19
GO:0003279	cardiac septum development	17/2053	103/18722	0.055802843289805	0.158605902292198	LRP2/NRP2/BMP7/ENG/NOTCH1/LMO4/ADAMTS6/GJA5/NRP1/ISL1/NOTCH2/SOX4/GATA3/CNTRL/LUZP1/TGFBR3/TBX3	17
GO:0060485	mesenchyme development	41/2053	291/18722	0.0558725224094976	0.158728756845164	S100A4/TGFB1/FLNA/MEF2C/FN1/HNRNPAB/IL1B/STAT1/GLIPR2/NRP2/DAG1/BMP7/LAMA5/ENG/SEMA4A/NOTCH1/ZFP36L1/LDLRAD4/SEMA6A/EZH2/NRP1/ISL1/HDAC2/RGCC/GATA3/DLG5/FOLR1/SDCBP/SEMA6D/TCOF1/EFNA1/YAP1/FERMT2/CORO1C/FOXC1/TRIM28/MDK/TGFBR3/DPPA4/BASP1/TBX3	41
GO:0009746	response to hexose	32/2053	219/18722	0.0559626867794715	0.158834494170685	TXNIP/HLA-DRB1/LGALS1/CYBA/SLC8A1/UCP2/SERPINF1/NAMPT/KRT18/GLUL/MPC2/TREM2/PTK2B/ICAM1/CTSV/SLC29A1/GJA1/HMGN3/KLF7/LDHA/RHOA/SOX4/GCLM/LRP5/FIS1/PHPT1/BAD/IGF1R/TRA2B/ENSA/NME1/CCDC186	32
GO:0034764	positive regulation of transmembrane transport	32/2053	219/18722	0.0559626867794715	0.158834494170685	CTSS/TMSB4X/FLNA/TCAF1/PTAFR/CCR2/CXCL10/C3/GLRX/MEF2A/IFNGR2/ITGB1/TREM2/KCNQ1/P2RX7/VMP1/KCNMB1/KCNE3/CHP1/CALM2/ANK3/KCNN4/RAP1A/RHOQ/SLC9A1/DMD/INSR/AKAP9/MAPK14/ACTN4/GPC3/COX17	32
GO:0033500	carbohydrate homeostasis	37/2053	259/18722	0.0563305605361543	0.159803008613204	HLA-DRB1/LGALS1/CYBA/UCP2/ALOX5/SERPINF1/MPC2/NUCKS1/TREM2/HK3/PDK4/ICAM1/OAS1/HK2/SLC29A1/FAM3B/HMGN3/KLF7/FABP5/STAT3/SOX4/SLC16A1/GCLM/RPS6/LRP5/CYB5R4/FIS1/ASPSCR1/PARK7/PHPT1/BAD/IGF1R/TRA2B/INSR/NME1/CCDC186/PPARG	37
GO:0000422	autophagy of mitochondrion	14/2053	81/18722	0.0564558990584852	0.159931725378145	TSPO/SLC25A5/HK2/BNIP3L/PHB2/SLC25A4/VDAC1/VPS13C/FIS1/PARK7/BNIP3/GABARAP/HUWE1/WIPI2	14
GO:0001960	negative regulation of cytokine-mediated signaling pathway	14/2053	81/18722	0.0564558990584852	0.159931725378145	PTPRC/ISG15/SAMHD1/IRAK3/GSTP1/IL1RN/CARD16/TREM2/SH2B3/OAS1/NLRC5/STAT2/PARP14/PPARG	14
GO:0061726	mitochondrion disassembly	14/2053	81/18722	0.0564558990584852	0.159931725378145	TSPO/SLC25A5/HK2/BNIP3L/PHB2/SLC25A4/VDAC1/VPS13C/FIS1/PARK7/BNIP3/GABARAP/HUWE1/WIPI2	14
GO:0016525	negative regulation of angiogenesis	23/2053	149/18722	0.0574275838303986	0.162607599331001	KLF4/KLF2/ALOX5/TNF/SERPINF1/STAT1/CCR2/CXCL10/VASH1/SEMA4A/HHEX/COL4A2/SEMA6A/STAB1/ADAMTS1/AMOT/RGCC/EPN2/FOXO4/FOXC1/PLK2/PTN/PPARG	23
GO:0007040	lysosome organization	13/2053	74/18722	0.0577982903417186	0.163145079577686	LAPTM5/CORO1A/LRRK2/GRN/LYST/PPT1/TPP1/SYT7/HOOK2/GAA/AKTIP/HEXB/MYO7A	13
GO:0046323	glucose import	13/2053	74/18722	0.0577982903417186	0.163145079577686	SLC2A3/TNF/SLC2A1/MEF2A/HK2/RAP1A/ASPSCR1/RHOQ/INSR/PEA15/MAPK14/PRKAG2/GPC3	13
GO:0080171	lytic vacuole organization	13/2053	74/18722	0.0577982903417186	0.163145079577686	LAPTM5/CORO1A/LRRK2/GRN/LYST/PPT1/TPP1/SYT7/HOOK2/GAA/AKTIP/HEXB/MYO7A	13
GO:0016233	telomere capping	8/2053	39/18722	0.0578077398636935	0.163145079577686	PRKDC/PKIB/HNRNPD/RAD50/PNKP/ERCC1/AURKB/MAP3K4	8
GO:0031507	heterochromatin assembly	8/2053	39/18722	0.0578077398636935	0.163145079577686	HELLS/DNMT1/TPR/POLE3/TRIM28/MBD2/MBD3/SMARCA5	8
GO:0045622	regulation of T-helper cell differentiation	8/2053	39/18722	0.0578077398636935	0.163145079577686	HLA-DRA/HLA-DRB1/CD86/NLRP3/RARA/BCL6/NFKBIZ/IL18	8
GO:1902742	apoptotic process involved in development	8/2053	39/18722	0.0578077398636935	0.163145079577686	TNFRSF1B/SPI1/BMP7/NOTCH1/CHEK1/VDR/LRP5/FOXC1	8
GO:0006006	glucose metabolic process	29/2053	196/18722	0.0580790794497252	0.163498142025231	HMGB1/FBP1/PHLDA2/TNF/SDS/PGP/SERP1/HK3/KCNQ1/PDK4/OAS1/HK2/SLC35B4/PMAIP1/DCXR/DDB1/SLC25A1/FABP5/LRP5/PDHA1/BAD/GAA/MIDN/C1QTNF1/LCMT1/ATF3/INSR/MAPK14/GAPDH	29
GO:0090276	regulation of peptide hormone secretion	29/2053	196/18722	0.0580790794497252	0.163498142025231	HLA-DRB1/EGFR/UCP2/JAK2/ALOX5/TNF/IL1B/GLUL/MPC2/SERP1/DPP4/GJA1/HMGN3/UQCC2/TRPM2/KLF7/ISL1/SYT7/SOX4/HADH/ACSL4/SLC16A1/LRP5/PHPT1/BAD/TCIRG1/MIDN/ENSA/TM7SF3	29
GO:0002418	immune response to tumor cell	6/2053	26/18722	0.0581780888706446	0.163498142025231	HLA-A/HLA-DRB1/HAVCR2/HMGB1/HSPD1/IL4I1	6
GO:0002710	negative regulation of T cell mediated immunity	6/2053	26/18722	0.0581780888706446	0.163498142025231	PTPRC/HLA-F/NCKAP1L/LILRB1/LILRB4/IL4I1	6
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	6/2053	26/18722	0.0581780888706446	0.163498142025231	TNFAIP3/TLR4/NFKBIA/SLC15A3/BIRC3/HSPA1A	6
GO:0045672	positive regulation of osteoclast differentiation	6/2053	26/18722	0.0581780888706446	0.163498142025231	TYROBP/FOS/CCR1/TNF/TREM2/NOTCH2	6
GO:0051016	barbed-end actin filament capping	6/2053	26/18722	0.0581780888706446	0.163498142025231	CAPG/RDX/TWF2/SCIN/EPS8/TRIOBP	6
GO:0051560	mitochondrial calcium ion homeostasis	6/2053	26/18722	0.0581780888706446	0.163498142025231	TGM2/IMMT/AFG3L2/FIS1/MCUR1/BNIP3	6
GO:0070920	regulation of production of small RNA involved in gene silencing by RNA	6/2053	26/18722	0.0581780888706446	0.163498142025231	TGFB1/EGFR/TNF/LIN28B/STAT3/NCOR2	6
GO:0002756	MyD88-independent toll-like receptor signaling pathway	4/2053	14/18722	0.0587822330530078	0.163662829845961	TLR4/CD300LF/IRF7/TLR6	4
GO:0002829	negative regulation of type 2 immune response	4/2053	14/18722	0.0587822330530078	0.163662829845961	CCR2/STAT6/IL27RA/BCL6	4
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	4/2053	14/18722	0.0587822330530078	0.163662829845961	HLA-E/C3/BTK/PARK7	4
GO:0006596	polyamine biosynthetic process	4/2053	14/18722	0.0587822330530078	0.163662829845961	OAZ1/SAT1/SMS/SRM	4
GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	4/2053	14/18722	0.0587822330530078	0.163662829845961	DUT/UPP1/TYMS/UMPS	4
GO:0009158	ribonucleoside monophosphate catabolic process	4/2053	14/18722	0.0587822330530078	0.163662829845961	UPP1/DPYD/PNP/AMPD3	4
GO:0010421	hydrogen peroxide-mediated programmed cell death	4/2053	14/18722	0.0587822330530078	0.163662829845961	MET/PAWR/PARK7/TRAP1	4
GO:0019321	pentose metabolic process	4/2053	14/18722	0.0587822330530078	0.163662829845961	DCXR/UXS1/RPIA/NUDT5	4
GO:0032688	negative regulation of interferon-beta production	4/2053	14/18722	0.0587822330530078	0.163662829845961	PYCARD/LILRB1/SIRPA/REL	4
GO:0035437	maintenance of protein localization in endoplasmic reticulum	4/2053	14/18722	0.0587822330530078	0.163662829845961	HSPA5/GJA1/GPAA1/KDELR2	4
GO:0043558	regulation of translational initiation in response to stress	4/2053	14/18722	0.0587822330530078	0.163662829845961	NPM1/EIF2AK4/EIF2AK1/PPP1R15A	4
GO:0046655	folic acid metabolic process	4/2053	14/18722	0.0587822330530078	0.163662829845961	DHFR/FOLR1/SLC19A1/SHMT1	4
GO:0048291	isotype switching to IgG isotypes	4/2053	14/18722	0.0587822330530078	0.163662829845961	PTPRC/HSPD1/IL27RA/MSH2	4
GO:0061043	regulation of vascular wound healing	4/2053	14/18722	0.0587822330530078	0.163662829845961	CXCR4/ALOX5/TNF/TNFAIP3	4
GO:0070141	response to UV-A	4/2053	14/18722	0.0587822330530078	0.163662829845961	TIMP1/EGFR/MME/CCND1	4
GO:0070278	extracellular matrix constituent secretion	4/2053	14/18722	0.0587822330530078	0.163662829845961	TNFRSF1B/ENG/NOTCH1/RGCC	4
GO:0070986	left/right axis specification	4/2053	14/18722	0.0587822330530078	0.163662829845961	NOTCH1/HSPB11/NOTCH2/AHI1	4
GO:0072531	pyrimidine-containing compound transmembrane transport	4/2053	14/18722	0.0587822330530078	0.163662829845961	AQP9/SLC29A1/SLC25A36/SLC19A3	4
GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	4/2053	14/18722	0.0587822330530078	0.163662829845961	CD74/CD44/TRIAP1/ING2	4
GO:2001171	positive regulation of ATP biosynthetic process	4/2053	14/18722	0.0587822330530078	0.163662829845961	TMSB4X/TREM2/STAT3/VCP	4
GO:0090150	establishment of protein localization to membrane	37/2053	260/18722	0.0590083381030951	0.164216154275775	ITGB2/NCF1/VAMP5/EGFR/ITGAM/TCAF1/CD24/KRT18/HSP90AA1/NSG1/CSK/CCDC47/HSPA5/ZDHHC12/TIMM13/HRAS/CHP1/CIB1/PARD3/GOLGA4/PDCD5/MYO1C/SDCBP/ANK3/RAB3IP/SPTBN1/ICMT/SEC63/GOPC/FIS1/NMT1/SGTB/RILPL2/SIL1/NACA/NDUFA13/CLSTN1	37
GO:0006195	purine nucleotide catabolic process	9/2053	46/18722	0.0593758782047567	0.165009388248513	SAMHD1/HINT1/PDE4A/NUDT8/NUDT15/PNP/NUDT4/AMPD3/DNPH1	9
GO:0055010	ventricular cardiac muscle tissue morphogenesis	9/2053	46/18722	0.0593758782047567	0.165009388248513	TGFB1/LRP2/DSP/ENG/NOTCH1/ISL1/FKBP1A/FOXC1/TGFBR3	9
GO:2000107	negative regulation of leukocyte apoptotic process	9/2053	46/18722	0.0593758782047567	0.165009388248513	CD74/TSC22D3/LILRB1/IRF7/BCL6/SLC39A10/EFNA1/HCLS1/AURKB	9
GO:0031638	zymogen activation	11/2053	60/18722	0.0596407690863132	0.16551554788061	PYCARD/CTSL/PERP/IFI16/RUNX1/CTSH/CTSZ/DHCR24/ASPH/BAD/PRSS12	11
GO:0035825	homologous recombination	11/2053	60/18722	0.0596407690863132	0.16551554788061	TOP2A/NUCKS1/RAD51AP1/RAD51/RAD51C/RAD21/MND1/FANCD2/RAD50/PSMC3IP/TOP2B	11
GO:1903670	regulation of sprouting angiogenesis	11/2053	60/18722	0.0596407690863132	0.16551554788061	HMGB1/KLF4/VEGFA/ITGA5/KLF2/ALOX5/JAK1/GLUL/SEMA6A/EPN2/TJP1	11
GO:0010506	regulation of autophagy	44/2053	317/18722	0.0600569999214862	0.165975332204158	TSPO/MTDH/PYCARD/IL10RA/TRIM22/PSAP/HMGB1/LRRK2/CASP1/IFI16/HMOX1/NAMPT/PLK3/MET/QSOX1/SLC25A5/TREM2/BNIP3L/PHB2/MCL1/ATP6V1C2/CISD1/STAT3/USP10/RHEB/SLC25A4/RALB/SVIP/CAPNS1/TRIM38/VDAC1/VPS13C/SCOC/PARK7/ATP6V1B1/BAD/BNIP3/ATP6V1B2/SNRNP70/PLK2/CAPN1/ATP6V0E1/EIF4G1/GAPDH	44
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	5/2053	20/18722	0.0602490455901093	0.165975332204158	BRD4/BACH1/ID2/E2F1/E2F7	5
GO:0001832	blastocyst growth	5/2053	20/18722	0.0602490455901093	0.165975332204158	RTF1/CHEK1/BRCA2/SBDS/NCAPG2	5
GO:0002834	regulation of response to tumor cell	5/2053	20/18722	0.0602490455901093	0.165975332204158	HLA-DRB1/HAVCR2/HMGB1/HSPD1/IL4I1	5
GO:0002837	regulation of immune response to tumor cell	5/2053	20/18722	0.0602490455901093	0.165975332204158	HLA-DRB1/HAVCR2/HMGB1/HSPD1/IL4I1	5
GO:0003159	morphogenesis of an endothelium	5/2053	20/18722	0.0602490455901093	0.165975332204158	CXCR4/CXCL10/ITGAX/RHOA/RHOB	5
GO:0006346	DNA methylation-dependent heterochromatin assembly	5/2053	20/18722	0.0602490455901093	0.165975332204158	HELLS/DNMT1/TRIM28/MBD2/MBD3	5
GO:0006851	mitochondrial calcium ion transmembrane transport	5/2053	20/18722	0.0602490455901093	0.165975332204158	VDAC1/STOML2/AFG3L2/MCUR1/PMPCB	5
GO:0010042	response to manganese ion	5/2053	20/18722	0.0602490455901093	0.165975332204158	TSPO/SOD2/LRRK2/APP/HSPA5	5
GO:0032986	protein-DNA complex disassembly	5/2053	20/18722	0.0602490455901093	0.165975332204158	SUPT16H/RPL23/SET/HMGA1/SMARCC1	5
GO:0051900	regulation of mitochondrial depolarization	5/2053	20/18722	0.0602490455901093	0.165975332204158	TSPO/LRRK2/PARP1/IFI6/GCLM	5
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	5/2053	20/18722	0.0602490455901093	0.165975332204158	ISG15/SAMHD1/OAS1/NLRC5/STAT2	5
GO:0061154	endothelial tube morphogenesis	5/2053	20/18722	0.0602490455901093	0.165975332204158	CXCR4/CXCL10/ITGAX/RHOA/RHOB	5
GO:0071731	response to nitric oxide	5/2053	20/18722	0.0602490455901093	0.165975332204158	CCNA2/TXN/HNRNPD/CDK2/MTR	5
GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	5/2053	20/18722	0.0602490455901093	0.165975332204158	GPX1/SOD2/PPIA/PARK7/TRAP1	5
GO:1903206	negative regulation of hydrogen peroxide-induced cell death	5/2053	20/18722	0.0602490455901093	0.165975332204158	LRRK2/MET/TXN/PARK7/TRAP1	5
GO:0014909	smooth muscle cell migration	16/2053	97/18722	0.062431498695289	0.171908670110938	AIF1/SORL1/MEF2C/TLR4/GSTP1/DOCK4/S100A11/ADAMTS1/TRIB1/NRP1/RHOA/SEMA6D/FOXO4/APEX1/MDK/PDGFA	16
GO:0030307	positive regulation of cell growth	25/2053	166/18722	0.0627198165363433	0.172623348265165	S100A8/CXCR4/CYBA/FN1/EGFR/VEGFA/CXCL16/S100A9/PTK2B/HAMP/TRPV2/HBEGF/ITSN2/NRP1/SPHK1/RHOA/CIB1/RPS6KA1/GOLGA4/TWF2/SDCBP/PARP2/SLC9A1/DNPH1/EIF4G1	25
GO:0001975	response to amphetamine	7/2053	33/18722	0.0630817655262507	0.17298473179045	NR4A2/RGS10/SOD1/NR4A1/ICAM1/HDAC2/RGS2	7
GO:0006336	DNA replication-independent nucleosome assembly	7/2053	33/18722	0.0630817655262507	0.17298473179045	NASP/CENPW/ASF1B/RBBP4/HAT1/ITGB3BP/MIS18A	7
GO:0031116	positive regulation of microtubule polymerization	7/2053	33/18722	0.0630817655262507	0.17298473179045	RPS3/MET/CLIP1/ARL2/HSPA1A/AKAP9/DRG1	7
GO:0033198	response to ATP	7/2053	33/18722	0.0630817655262507	0.17298473179045	SLC8A1/HSP90B1/CASP1/HSPD1/SOD1/P2RX7/P2RY11	7
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	7/2053	33/18722	0.0630817655262507	0.17298473179045	TGFB1/LYN/FGR/PTK2B/FLT1/VAV3/PTK2	7
GO:0046685	response to arsenic-containing substance	7/2053	33/18722	0.0630817655262507	0.17298473179045	SERPINF1/HMOX1/HNRNPA1/CDKN1A/ATF3/VCP/ALAD	7
GO:1902692	regulation of neuroblast proliferation	7/2053	33/18722	0.0630817655262507	0.17298473179045	LRRK2/VEGFA/NOTCH1/ASPM/CX3CR1/GLI3/PTN	7
GO:1903715	regulation of aerobic respiration	7/2053	33/18722	0.0630817655262507	0.17298473179045	UQCC2/RHOA/ARL2/COX7A2/PARK7/BNIP3/VCP	7
GO:0043627	response to estrogen	13/2053	75/18722	0.0632051098810402	0.173085650062182	HSPD1/HMOX1/CD24/RARA/DTYMK/COMT/CCND1/BRCA1/LDHA/GATA3/TRIM24/GLI3/ARID5A	13
GO:0048662	negative regulation of smooth muscle cell proliferation	13/2053	75/18722	0.0632051098810402	0.173085650062182	AIF1/MEF2C/KLF4/SOD2/TNFAIP3/GSTP1/HMOX1/COMT/TRIB1/RHOA/SF1/CDKN1A/PPARG	13
GO:1903363	negative regulation of cellular protein catabolic process	13/2053	75/18722	0.0632051098810402	0.173085650062182	RPS7/HSP90AB1/RPL5/RPL23/PBK/SMARCC1/SDCBP/ATRAID/EFNA1/USP14/SVIP/PARK7/ALAD	13
GO:0051604	protein maturation	41/2053	294/18722	0.0636222941695059	0.17414861542748	CTSS/SRGN/PYCARD/SORL1/LRRK2/CTSL/PERP/CASP1/IFI16/HSPD1/PARP1/GCSH/PRDX4/RUNX1/CTSH/CTSZ/CARD16/MME/CALR/ADAM8/DHCR24/SERPINH1/ENPEP/ASPH/SPCS2/GLRX5/SOX4/BCL2L12/NDUFAB1/BAG2/STOML2/MAGEF1/AFG3L2/CIAO1/BAD/FKBP1A/PRSS12/ISCA1/PISD/GLI3/PMPCB	41
GO:0072655	establishment of protein localization to mitochondrion	19/2053	120/18722	0.064053646184811	0.175249373966651	TSPO/RAC2/LRRK2/LMAN1/HSPD1/HSP90AA1/HK2/BNIP3L/TIMM13/TOMM40/PDCD5/TOMM34/DNAJC19/SAE1/FIS1/NMT1/PMPCB/HUWE1/NDUFA13	19
GO:0046390	ribose phosphate biosynthetic process	28/2053	190/18722	0.06424944094483	0.175704943331349	TMSB4X/TGFB1/UPP1/PARP1/SLC26A2/MPC2/ACSS1/TECR/TREM2/PDK4/PAICS/PPT1/ALDOA/SLC25A1/UMPS/STAT3/ACSL4/GMPS/PDHA1/STOML2/NME4/ADK/IMPDH2/AMPD3/VCP/NME1/PPAT/PRKAG2	28
GO:0002028	regulation of sodium ion transport	15/2053	90/18722	0.0646662291665054	0.176521439900825	FXYD5/SLC8A1/FXYD3/GLRX/KCNQ1/P2RX7/CAMK2D/CHP1/ANK3/SLC9A1/COMMD1/DLG1/DMD/PTPN3/ACTN4	15
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	12/2053	68/18722	0.0646951077236522	0.176521439900825	TMSB4X/TGFB1/PARP1/TREM2/ALDOA/STAT3/STOML2/NME4/IMPDH2/VCP/NME1/PRKAG2	12
GO:0010812	negative regulation of cell-substrate adhesion	12/2053	68/18722	0.0646951077236522	0.176521439900825	LGALS1/FBLN1/GBP1/NOTCH1/BCL6/RASA1/KANK1/TACSTD2/RHOA/CDKN2A/CORO1C/ACTN4	12
GO:0032922	circadian regulation of gene expression	12/2053	68/18722	0.0646951077236522	0.176521439900825	NAMPT/MAGED1/ID1/HDAC2/BHLHE40/LGR4/ID3/ID4/ID2/BHLHE41/GFPT1/HUWE1	12
GO:0042698	ovulation cycle	12/2053	68/18722	0.0646951077236522	0.176521439900825	EGFR/RETN/PCNA/SERPINF1/ARRB2/HSPA5/ADAMTS1/TRPM2/NCOR2/MDK/PTN/PLEKHA1	12
GO:2000181	negative regulation of blood vessel morphogenesis	23/2053	151/18722	0.0648982237295163	0.176995155625953	KLF4/KLF2/ALOX5/TNF/SERPINF1/STAT1/CCR2/CXCL10/VASH1/SEMA4A/HHEX/COL4A2/SEMA6A/STAB1/ADAMTS1/AMOT/RGCC/EPN2/FOXO4/FOXC1/PLK2/PTN/PPARG	23
GO:0050808	synapse organization	57/2053	426/18722	0.0653246067801343	0.178077074366563	SRGN/FLNA/C5AR1/LILRB2/MEF2C/IL10RA/TLR2/TUBA1A/ACTB/ABI3/LRRK2/DOCK10/ITGAM/TUBB/CDH1/TNF/MYH10/APP/C3/NRP2/DAG1/CAMK1/SEMA4A/TREM2/C1QA/ZDHHC12/CX3CR1/TPBG/HSPA8/NRP1/STAU1/RHOA/ACTR2/DLG5/SDCBP/ANK3/COL4A1/EFNA1/PTPRF/CHCHD10/AFG3L2/WASF2/PFN1/OBSL1/DLG1/IGF1R/CHRNB1/INSR/VCP/PTN/CFL1/PPFIBP1/NDRG1/EIF4G1/CLSTN1/HOMER1/MAPK14	57
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	20/2053	128/18722	0.0655789206342069	0.178375416034069	NCF1/SPI1/CLEC7A/PYCARD/LYN/SCIMP/HMGB1/VEGFA/TNF/TLR4/IL1B/APP/GADD45B/PTK2B/HRAS/SPHK1/SDCBP/MYD88/RASSF2/MAP3K4	20
GO:0014037	Schwann cell differentiation	8/2053	40/18722	0.0656124238645318	0.178375416034069	DAG1/SOD1/CDK1/ITGB4/PARD3/GPC1/ADGRG6/NDRG1	8
GO:0045022	early endosome to late endosome transport	8/2053	40/18722	0.0656124238645318	0.178375416034069	MSN/FLNA/EMP2/RDX/HOOK2/EZR/AKTIP/EEA1	8
GO:0071526	semaphorin-plexin signaling pathway	8/2053	40/18722	0.0656124238645318	0.178375416034069	FLNA/PLXNC1/MET/NRP2/SEMA4A/SEMA6A/NRP1/SEMA6D	8
GO:1901223	negative regulation of NIK/NF-kappaB signaling	8/2053	40/18722	0.0656124238645318	0.178375416034069	TMSB4X/SPI1/NLRP3/BMP7/LITAF/NLRP12/IFI35/RASSF2	8
GO:1901998	toxin transport	8/2053	40/18722	0.0656124238645318	0.178375416034069	CASP1/HSPA5/NRP1/TCP1/CCT2/BNIP3/CCT4/CCT8	8
GO:0071384	cellular response to corticosteroid stimulus	11/2053	61/18722	0.0658709387998452	0.178997116303927	ZFP36/ZFP36L2/EGFR/SERPINF1/GSTP1/ZFP36L1/ATP2B1/ICAM1/DDIT4/ISL1/ASS1	11
GO:0006417	regulation of translation	62/2053	468/18722	0.0663741803839353	0.180179984291567	VIM/ZFP36/ZFP36L2/TYMS/TNF/APP/PTAFR/EIF1/PA2G4/RPS3/PRKDC/PABPC1/RPS14/RPL5/RARA/SERP1/CALR/ZFP36L1/NPM1/PTK2B/DHFR/HNRNPR/BTG2/IGF2BP3/EXOSC8/RPL13A/C1QBP/UQCC2/RHOA/RPS6KA1/STAT3/SOX4/HNRNPD/UPF3A/RPS9/CDK4/TSFM/MAGOH/KHSRP/TPR/TCOF1/EIF5B/EIF2AK4/NCL/RGS2/DDX1/EIF2AK1/EIF5/PPP1R15A/AGO2/DNAJC1/SHMT1/MALSU1/ASCC3/TIA1/RPS4X/TRAP1/LRPPRC/PURA/EIF4G1/YBX1/GAPDH	62
GO:0034767	positive regulation of ion transmembrane transport	25/2053	167/18722	0.0664041545547612	0.180179984291567	CTSS/TMSB4X/FLNA/TCAF1/PTAFR/CCR2/CXCL10/GLRX/IFNGR2/ITGB1/TREM2/KCNQ1/P2RX7/VMP1/KCNMB1/KCNE3/CHP1/CALM2/ANK3/KCNN4/SLC9A1/DMD/AKAP9/ACTN4/COX17	25
GO:0030834	regulation of actin filament depolymerization	10/2053	54/18722	0.0665817685734567	0.180179984291567	PLEK/CAPG/DSTN/RDX/TWF2/SCIN/SPTBN1/EPS8/LIMA1/TRIOBP	10
GO:0070839	metal ion export	10/2053	54/18722	0.0665817685734567	0.180179984291567	SLC11A1/SLC8A1/SLC40A1/ATP2B1/KCNQ1/KCNE3/CALM2/YWHAE/SLC9A1/DLG1	10
GO:1902743	regulation of lamellipodium organization	10/2053	54/18722	0.0665817685734567	0.180179984291567	CD44/WAS/RAC2/ABI3/KANK1/ACTR2/TWF2/ACTR3/WASF2/CORO1C	10
GO:0010799	regulation of peptidyl-threonine phosphorylation	9/2053	47/18722	0.0666065341931158	0.180179984291567	TGFB1/APP/BMP7/DDIT4/SPHK1/CALM2/PARD3/EIF4G1/PRKAG2	9
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	9/2053	47/18722	0.0666065341931158	0.180179984291567	LAPTM5/PYCARD/CASP1/TNFAIP3/GSTP1/SYK/CARD16/SPHK1/HSPA1A	9
GO:0014911	positive regulation of smooth muscle cell migration	9/2053	47/18722	0.0666065341931158	0.180179984291567	AIF1/TLR4/DOCK4/S100A11/ADAMTS1/NRP1/SEMA6D/FOXO4/MDK	9
GO:0035850	epithelial cell differentiation involved in kidney development	9/2053	47/18722	0.0666065341931158	0.180179984291567	MEF2C/STAT1/CD24/NOTCH1/NOTCH2/GATA3/YAP1/BASP1/ASXL1	9
GO:0050798	activated T cell proliferation	9/2053	47/18722	0.0666065341931158	0.180179984291567	LGALS9/PYCARD/LILRB4/HMGB1/RPS3/CD24/IL27RA/BTN3A1/IL18	9
GO:0071347	cellular response to interleukin-1	18/2053	113/18722	0.0668058811900849	0.180637804029071	CCL3L3/CCL3/CCL4/PYCARD/GBP2/KLF2/IRAK3/IL1B/GBP1/CEBPB/IL1RN/ICAM1/CXCL8/USP10/SIRPA/MYD88/RBMX/RPS6KA5	18
GO:0051899	membrane depolarization	14/2053	83/18722	0.0668513193800032	0.180679241567576	TSPO/SLC8A1/LRRK2/CASP1/PARP1/IFI6/P2RX7/CAMK2D/GJA5/GCLM/ANK3/JUN/PARK7/PTPN3	14
GO:0055074	calcium ion homeostasis	61/2053	460/18722	0.0670950039886966	0.181256201680405	PTPRC/CXCR4/CD52/CORO1A/CCL3/CYBA/FPR1/C5AR1/LYN/FPR3/SLC8A1/C3AR1/GPR65/HMGB1/JAK2/LPAR6/SNX10/CCR1/HSP90B1/CD36/APP/CCR2/PTGER4/CXCL10/CD24/S1PR4/TGM2/PTPN6/CCRL2/CALR/CCDC47/ATP2B1/PTK2B/TRPV2/P2RX7/GNA15/CYSLTR1/PRKCB/GJA1/CX3CR1/CAMK2D/TRPM2/CALM2/MCOLN3/VDR/ITGAV/IMMT/TRIM24/STOML2/AFG3L2/FIS1/YWHAE/ATP6V1B1/MCUR1/DMD/TCIRG1/BNIP3/FKBP1A/C1QTNF1/UBASH3B/HEXB	61
GO:0002825	regulation of T-helper 1 type immune response	6/2053	27/18722	0.0681439306548964	0.183018614113419	SLC11A1/HAVCR2/IL1B/CCR2/IL27RA/IL18	6
GO:0008053	mitochondrial fusion	6/2053	27/18722	0.0681439306548964	0.183018614113419	STOML2/AFG3L2/FIS1/BNIP3/TFRC/HUWE1	6
GO:0010758	regulation of macrophage chemotaxis	6/2053	27/18722	0.0681439306548964	0.183018614113419	CSF1R/C5AR1/C3AR1/PTK2B/MDK/PTK2	6
GO:0031954	positive regulation of protein autophosphorylation	6/2053	27/18722	0.0681439306548964	0.183018614113419	VEGFA/GPNMB/CALM2/RAD50/RASSF2/PDGFA	6
GO:0034143	regulation of toll-like receptor 4 signaling pathway	6/2053	27/18722	0.0681439306548964	0.183018614113419	LYN/HMGB1/TNFAIP3/LILRA2/TREM2/IFI35	6
GO:0034698	response to gonadotropin	6/2053	27/18722	0.0681439306548964	0.183018614113419	NOTCH1/ICAM1/CTSV/CCNA2/GCLM/TGFBR3	6
GO:0042104	positive regulation of activated T cell proliferation	6/2053	27/18722	0.0681439306548964	0.183018614113419	PYCARD/HMGB1/RPS3/CD24/IL27RA/IL18	6
GO:0042402	cellular biogenic amine catabolic process	6/2053	27/18722	0.0681439306548964	0.183018614113419	KYNU/SAT1/IL4I1/ALDH7A1/COMT/SLC44A1	6
GO:0045830	positive regulation of isotype switching	6/2053	27/18722	0.0681439306548964	0.183018614113419	PTPRC/TGFB1/STAT6/MSH2/RIF1/TFRC	6
GO:0061437	renal system vasculature development	6/2053	27/18722	0.0681439306548964	0.183018614113419	PECAM1/BMP7/NOTCH1/IL6R/NRP1/NOTCH2	6
GO:0061440	kidney vasculature development	6/2053	27/18722	0.0681439306548964	0.183018614113419	PECAM1/BMP7/NOTCH1/IL6R/NRP1/NOTCH2	6
GO:1902883	negative regulation of response to oxidative stress	6/2053	27/18722	0.0681439306548964	0.183018614113419	LRRK2/MET/MCTP1/TXN/PARK7/TRAP1	6
GO:1903205	regulation of hydrogen peroxide-induced cell death	6/2053	27/18722	0.0681439306548964	0.183018614113419	LRRK2/MET/PAWR/TXN/PARK7/TRAP1	6
GO:0031669	cellular response to nutrient levels	31/2053	215/18722	0.0682414573696308	0.183198543274177	CD68/UCP2/UPP1/LRRK2/IFI16/HMOX1/NAMPT/SLC2A1/GLUL/ATP2B1/PDK4/COMT/HSPA5/ICAM1/CTSV/HNRNPA1/HSPA8/PMAIP1/VDR/FOLR1/RALB/TRIM24/EIF2AK4/JUN/CDKN1A/ATF3/PTN/GABARAP/EIF4G1/WIPI2/PRKAG2	31
GO:0043500	muscle adaptation	19/2053	121/18722	0.0685172212554194	0.183774397645291	AIF1/CYBA/TNFRSF1B/KLF4/PARP1/IL1B/HMOX1/MEF2A/DAG1/NOTCH1/HAMP/EZH2/CAMK2D/IL6ST/PARP2/RGS2/SLC9A1/CAMK2G/LMNA	19
GO:1904019	epithelial cell apoptotic process	19/2053	121/18722	0.0685172212554194	0.183774397645291	ZFP36/JAK2/TNF/TNFAIP3/ITGA4/HMOX1/ARRB2/KRT18/ZFP36L1/ICAM1/KRT8/RGCC/GATA3/YAP1/BAD/STK4/TIA1/MDK/E2F1	19
GO:1901343	negative regulation of vasculature development	23/2053	152/18722	0.0688760622577114	0.184654322406733	KLF4/KLF2/ALOX5/TNF/SERPINF1/STAT1/CCR2/CXCL10/VASH1/SEMA4A/HHEX/COL4A2/SEMA6A/STAB1/ADAMTS1/AMOT/RGCC/EPN2/FOXO4/FOXC1/PLK2/PTN/PPARG	23
GO:0006305	DNA alkylation	13/2053	76/18722	0.0689376196483153	0.184654338343702	SPI1/FOS/HELLS/PARP1/DNMT1/BRCA1/EZH2/KDM1B/MIS18A/KMT2E/TRIM28/MBD2/MBD3	13
GO:0006306	DNA methylation	13/2053	76/18722	0.0689376196483153	0.184654338343702	SPI1/FOS/HELLS/PARP1/DNMT1/BRCA1/EZH2/KDM1B/MIS18A/KMT2E/TRIM28/MBD2/MBD3	13
GO:0001824	blastocyst development	17/2053	106/18722	0.0696357074949904	0.186357825588734	NASP/SKIL/KLF4/JUNB/LPAR6/ASF1B/RRM2/RTF1/CMTM3/MFNG/CHEK1/BRCA2/YAP1/SBDS/RBBP8/ACTL6A/NCAPG2	17
GO:0090263	positive regulation of canonical Wnt signaling pathway	17/2053	106/18722	0.0696357074949904	0.186357825588734	ZEB2/TGFB1/EGFR/LRRK2/WLS/HHEX/RPS12/LGR5/ASPM/KANK1/SULF2/SOX4/LGR4/YAP1/TBL1X/VCP/GPC3	17
GO:0001657	ureteric bud development	15/2053	91/18722	0.0699327345522213	0.187069285471836	VEGFA/MAGED1/RARA/BMP7/LAMA5/TACSTD2/GATA3/PBX1/LGR4/DLG1/GLI3/FOXC1/SMAD5/BASP1/GPC3	15
GO:0043534	blood vessel endothelial cell migration	26/2053	176/18722	0.0707192470838833	0.189088895946212	TMSB4X/TGFB1/MEF2C/HMGB1/GPX1/KLF4/VEGFA/TNF/HMOX1/VASH1/ITGB1/NOTCH1/PTK2B/NR4A1/EMP2/STAT5A/ID1/AMOT/NRP1/RHOA/CIB1/RGCC/EPHB4/EFNA1/PLK2/PPARG	26
GO:0045665	negative regulation of neuron differentiation	12/2053	69/18722	0.0708558785039714	0.189285516929576	B2M/APP/BMP7/NOTCH1/CALR/ASPM/SLC6A4/ISL1/RHOA/PBX1/EIF2AK4/GLI3	12
GO:0070192	chromosome organization involved in meiotic cell cycle	12/2053	69/18722	0.0708558785039714	0.189285516929576	SMC2/RAD51/CCNE1/SMC4/RAD51C/RAD21/CCNE2/NCAPD3/FANCD2/RAD50/PSMC3IP/BUB1B	12
GO:0006986	response to unfolded protein	21/2053	137/18722	0.0711783661252138	0.190062392857714	HSPD1/HSP90AA1/HSP90AB1/SERP1/HSPE1/HSPA5/SERPINH1/CCND1/HSPA8/HSPA6/FBXO6/UBXN4/MANF/HSPA14/HSPA1A/PPP1R15A/ATF3/VCP/HSPA9/TM7SF3/DNAJB9	21
GO:0072522	purine-containing compound biosynthetic process	29/2053	200/18722	0.0715362011773428	0.190753941164115	TMSB4X/TGFB1/PARP1/SLC26A2/MPC2/ACSS1/TECR/TREM2/PDK4/PAICS/PPT1/ALDOA/SLC25A1/MTAP/STAT3/PNP/ACSL4/GMPS/PDHA1/STOML2/NME4/ADK/IMPDH2/AMPD3/SHMT1/VCP/NME1/PPAT/PRKAG2	29
GO:0051261	protein depolymerization	18/2053	114/18722	0.0715645202600705	0.190753941164115	PLEK/CAPG/STMN1/DSTN/HSPA8/RDX/CIB1/TPX2/CKAP2/TWF2/SCIN/MID1IP1/SPTBN1/EPS8/ARHGEF2/LIMA1/TRIOBP/CFL1	18
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	18/2053	114/18722	0.0715645202600705	0.190753941164115	ZEB2/TGFB1/JAK2/PARP1/HSP90AB1/BMP7/ENG/NOTCH1/CDKN1C/FERMT1/RBPMS/NOTCH2/SDCBP/TTK/ING2/TGFBR3/PPARG/GPC3	18
GO:1904892	regulation of receptor signaling pathway via STAT	18/2053	114/18722	0.0715645202600705	0.190753941164115	PTPRC/TGFB1/IL10RA/CD300A/JAK2/TNF/SOCS3/NOTCH1/IL6R/PTK2B/SH2B3/AKR1B1/SUZ12/CSH1/PARP14/CENPJ/PWP1/PPARG	18
GO:0019370	leukotriene biosynthetic process	5/2053	21/18722	0.0722170834136409	0.191042908388284	ALOX5AP/MGST3/ALOX5/SYK/LTA4H	5
GO:0019985	translesion synthesis	5/2053	21/18722	0.0722170834136409	0.191042908388284	PCNA/DTL/USP10/VCP/POLE2	5
GO:0033762	response to glucagon	5/2053	21/18722	0.0722170834136409	0.191042908388284	CDO1/CCNA2/ASS1/CYC1/QDPR	5
GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	5/2053	21/18722	0.0722170834136409	0.191042908388284	CTSL/STAT6/IL6R/SPN/STAT3	5
GO:0044766	multi-organism transport	5/2053	21/18722	0.0722170834136409	0.191042908388284	BST2/CTSL/IFIT1/SIGLEC1/DYNLT1	5
GO:0070269	pyroptosis	5/2053	21/18722	0.0722170834136409	0.191042908388284	CASP1/TREM2/AIM2/NAIP/NLRP1	5
GO:0071498	cellular response to fluid shear stress	5/2053	21/18722	0.0722170834136409	0.191042908388284	MEF2C/KLF4/KLF2/PTK2B/ASS1	5
GO:0072111	cell proliferation involved in kidney development	5/2053	21/18722	0.0722170834136409	0.191042908388284	STAT1/BMP7/IL6R/GATA3/GPC3	5
GO:0150146	cell junction disassembly	5/2053	21/18722	0.0722170834136409	0.191042908388284	ITGAM/C3/TREM2/C1QA/CX3CR1	5
GO:1902579	multi-organism localization	5/2053	21/18722	0.0722170834136409	0.191042908388284	BST2/CTSL/IFIT1/SIGLEC1/DYNLT1	5
GO:2000047	regulation of cell-cell adhesion mediated by cadherin	5/2053	21/18722	0.0722170834136409	0.191042908388284	VEGFA/NOTCH1/RGCC/TJP1/PTPRU	5
GO:2000178	negative regulation of neural precursor cell proliferation	5/2053	21/18722	0.0722170834136409	0.191042908388284	SPINT1/SPINT2/BTG2/SLC6A4/PTN	5
GO:0002183	cytoplasmic translational initiation	7/2053	34/18722	0.0722460598555029	0.191042908388284	RPL13A/EIF5/EIF3J/DENR/EIF3A/EIF4G1/EIF3L	7
GO:0030851	granulocyte differentiation	7/2053	34/18722	0.0722460598555029	0.191042908388284	EVI2B/SPI1/RUNX1/RARA/TRIB1/HCLS1/INPP5D	7
GO:0032770	positive regulation of monooxygenase activity	7/2053	34/18722	0.0722460598555029	0.191042908388284	TNF/IL1B/PTK2B/DHFR/VDR/PARK7/GCH1	7
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	7/2053	34/18722	0.0722460598555029	0.191042908388284	CD74/CD44/NPM1/PMAIP1/EEF1E1/SMYD2/KMT5A	7
GO:0086004	regulation of cardiac muscle cell contraction	7/2053	34/18722	0.0722460598555029	0.191042908388284	DSP/DSG2/CAMK2D/GJA5/DSC2/DLG1/AKAP9	7
GO:2000758	positive regulation of peptidyl-lysine acetylation	7/2053	34/18722	0.0722460598555029	0.191042908388284	IL1B/BRCA1/ISL1/SOX4/BRD7/GATA3/RPS6KA5	7
GO:1900542	regulation of purine nucleotide metabolic process	14/2053	84/18722	0.0724958682000822	0.191312116866123	TMSB4X/FBP1/PARP1/APP/TREM2/PDK4/P2RX7/DDIT4/SLC2A6/STAT3/ARL2/INSR/VCP/PRKAG2	14
GO:0007062	sister chromatid cohesion	11/2053	62/18722	0.0725072922922608	0.191312116866123	FEN1/SMC3/PHB2/RAD51C/CDCA5/RAD21/DSCC1/ESCO2/KIF22/STAG1/BUB1B	11
GO:0046173	polyol biosynthetic process	11/2053	62/18722	0.0725072922922608	0.191312116866123	PLEK/ISYNA1/PGP/PTAFR/PTK2B/DHFR/AKR1B1/SPHK1/IMPA2/GCH1/QDPR	11
GO:0046847	filopodium assembly	11/2053	62/18722	0.0725072922922608	0.191312116866123	FGD2/ITGB4/SPATA13/TRPM2/NRP1/FGD3/FNBP1L/RHOQ/EZR/FGD4/DOCK11	11
GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	11/2053	62/18722	0.0725072922922608	0.191312116866123	NSG1/DAG1/HRAS/RAP1A/YWHAE/EPS8/DLG1/NUMB/CTNND1/AP2M1/CLSTN1	11
GO:0001325	formation of extrachromosomal circular DNA	4/2053	15/18722	0.0734414797330132	0.192255182547155	BLM/XRCC5/ERCC1/EXO1	4
GO:0002070	epithelial cell maturation	4/2053	15/18722	0.0734414797330132	0.192255182547155	TYMS/AKR1B1/CDKN1A/TFCP2L1	4
GO:0006089	lactate metabolic process	4/2053	15/18722	0.0734414797330132	0.192255182547155	PNKD/LDHA/PARK7/MRS2	4
GO:0009163	nucleoside biosynthetic process	4/2053	15/18722	0.0734414797330132	0.192255182547155	DTYMK/MTAP/PNP/ADK	4
GO:0010763	positive regulation of fibroblast migration	4/2053	15/18722	0.0734414797330132	0.192255182547155	TGFB1/SLC8A1/ITGB1/PTK2	4
GO:0010940	positive regulation of necrotic cell death	4/2053	15/18722	0.0734414797330132	0.192255182547155	TSPO/SLC6A6/HEBP2/BNIP3	4
GO:0032486	Rap protein signal transduction	4/2053	15/18722	0.0734414797330132	0.192255182547155	TIMP2/RDX/RAP1A/PLK2	4
GO:0034404	nucleobase-containing small molecule biosynthetic process	4/2053	15/18722	0.0734414797330132	0.192255182547155	DTYMK/MTAP/PNP/ADK	4
GO:0042976	activation of Janus kinase activity	4/2053	15/18722	0.0734414797330132	0.192255182547155	CD300A/JAK2/IL6R/PTK2B	4
GO:0051315	attachment of mitotic spindle microtubules to kinetochore	4/2053	15/18722	0.0734414797330132	0.192255182547155	CDT1/NUF2/NDC80/AURKB	4
GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening	4/2053	15/18722	0.0734414797330132	0.192255182547155	ZFP36/PABPC1/BTG2/AGO2	4
GO:0086069	bundle of His cell to Purkinje myocyte communication	4/2053	15/18722	0.0734414797330132	0.192255182547155	DSP/DSG2/GJA5/DSC2	4
GO:0090656	t-circle formation	4/2053	15/18722	0.0734414797330132	0.192255182547155	BLM/XRCC5/ERCC1/EXO1	4
GO:0090737	telomere maintenance via telomere trimming	4/2053	15/18722	0.0734414797330132	0.192255182547155	BLM/XRCC5/ERCC1/EXO1	4
GO:0097468	programmed cell death in response to reactive oxygen species	4/2053	15/18722	0.0734414797330132	0.192255182547155	MET/PAWR/PARK7/TRAP1	4
GO:1905288	vascular associated smooth muscle cell apoptotic process	4/2053	15/18722	0.0734414797330132	0.192255182547155	SOD2/DNMT1/STK4/PPARG	4
GO:1905459	regulation of vascular associated smooth muscle cell apoptotic process	4/2053	15/18722	0.0734414797330132	0.192255182547155	SOD2/DNMT1/STK4/PPARG	4
GO:2000345	regulation of hepatocyte proliferation	4/2053	15/18722	0.0734414797330132	0.192255182547155	TNFAIP3/SULF2/MDK/PTN	4
GO:0043331	response to dsRNA	10/2053	55/18722	0.073748472487991	0.192974633636261	IFIT1/IRAK3/COLEC12/NFKBIA/NPM1/PMAIP1/RALB/DDX1/DDX58/SLC3A2	10
GO:0007099	centriole replication	8/2053	41/18722	0.0740370963070995	0.193476732509842	NPM1/BRCA1/CEP152/CDK2/CENPJ/SASS6/PLK2/CCP110	8
GO:0055023	positive regulation of cardiac muscle tissue growth	8/2053	41/18722	0.0740370963070995	0.193476732509842	MEF2C/CDK1/NOTCH1/HAMP/YAP1/PARP2/TGFBR3/MAPK14	8
GO:0060612	adipose tissue development	8/2053	41/18722	0.0740370963070995	0.193476732509842	SPI1/SORL1/UBB/KLF7/CDK4/LRP5/ARID5B/PGRMC2	8
GO:0015804	neutral amino acid transport	9/2053	48/18722	0.0743666589559524	0.194168822339301	SLC38A1/SLC6A6/SLC1A5/SFXN3/SFXN1/RGS2/SLC38A9/SLC38A6/SLC3A2	9
GO:0045005	DNA-dependent DNA replication maintenance of fidelity	9/2053	48/18722	0.0743666589559524	0.194168822339301	SAMHD1/PCNA/NUCKS1/RAD51/BLM/BRCA2/MMS22L/TIPIN/TIMELESS	9
GO:0021675	nerve development	13/2053	77/18722	0.0750002037371007	0.195652705401132	MAFB/ITGA4/NRP2/DAG1/CTSV/TFAP2A/SULF2/NRP1/ISL1/AFG3L2/TCIRG1/GLI3/SLC1A3	13
GO:0055117	regulation of cardiac muscle contraction	13/2053	77/18722	0.0750002037371007	0.195652705401132	SLC8A1/DSP/KCNQ1/DSG2/CAMK2D/GJA5/DSC2/CALM2/RGS2/SLC9A1/DLG1/DMD/AKAP9	13
GO:0065004	protein-DNA complex assembly	29/2053	201/18722	0.0752135810399273	0.196124070508285	NASP/HMGB1/HMGB2/HELLS/GMNN/DNAJC9/CENPW/CENPF/NPM1/RAD51/ASF1B/CENPN/SET/NAP1L1/CDT1/RBBP4/MCM2/RAD51C/HAT1/CENPK/ITGB3BP/CENPH/CHAF1A/CDC45/MIS18A/BDP1/NAP1L4/SMARCA5/KNTC1	29
GO:0072163	mesonephric epithelium development	15/2053	92/18722	0.0754759524063715	0.196637305444303	VEGFA/MAGED1/RARA/BMP7/LAMA5/TACSTD2/GATA3/PBX1/LGR4/DLG1/GLI3/FOXC1/SMAD5/BASP1/GPC3	15
GO:0072164	mesonephric tubule development	15/2053	92/18722	0.0754759524063715	0.196637305444303	VEGFA/MAGED1/RARA/BMP7/LAMA5/TACSTD2/GATA3/PBX1/LGR4/DLG1/GLI3/FOXC1/SMAD5/BASP1/GPC3	15
GO:0046916	cellular transition metal ion homeostasis	18/2053	115/18722	0.0765455291405117	0.199337315470082	S100A8/SLC11A1/FTH1/FTL/APP/HMOX1/SLC40A1/SCO2/SOD1/MT1X/S100A9/HAMP/SLC39A10/MT2A/ANKRD9/SLC39A7/SCO1/TFRC	18
GO:0030856	regulation of epithelial cell differentiation	23/2053	154/18722	0.0773279938896446	0.201287619669357	ZFP36/VEGFA/TNF/IL1B/STAT1/CEBPB/CD24/NOTCH1/ZFP36L1/CCND1/ID1/EZH2/BTG1/KLF7/AHI1/VDR/GATA3/YAP1/ESRP1/VCL/BAD/FOXC1/TBX3	23
GO:0032092	positive regulation of protein binding	14/2053	85/18722	0.0784433454369683	0.20401390230681	B2M/LRRK2/APP/RAN/HSP90AB1/MFNG/NRP1/RALB/DTX3L/FKBP1A/STK4/PLK2/AKTIP/EPB41	14
GO:0071277	cellular response to calcium ion	14/2053	85/18722	0.0784433454369683	0.20401390230681	MEF2C/FOS/ALOX5AP/JUNB/FUS/MEF2A/HSPA5/FOSB/CAMK2D/TRPM2/RASGRP2/SYT7/CACYBP/ECT2	14
GO:0000423	mitophagy	6/2053	28/18722	0.0790355303015059	0.205020830872908	SLC25A5/PHB2/SLC25A4/VDAC1/VPS13C/HUWE1	6
GO:0034123	positive regulation of toll-like receptor signaling pathway	6/2053	28/18722	0.0790355303015059	0.205020830872908	CYBA/TLR2/HMGB1/TLR1/RSAD2/IFI35	6
GO:0044331	cell-cell adhesion mediated by cadherin	6/2053	28/18722	0.0790355303015059	0.205020830872908	VEGFA/NOTCH1/RGCC/TJP1/CTNND1/PTPRU	6
GO:0062125	regulation of mitochondrial gene expression	6/2053	28/18722	0.0790355303015059	0.205020830872908	C1QBP/UQCC2/TSFM/CHCHD10/MALSU1/LRPPRC	6
GO:0080111	DNA demethylation	6/2053	28/18722	0.0790355303015059	0.205020830872908	APOBEC3A/APOBEC3G/APOBEC3C/GATA3/APEX1/TRIM28	6
GO:1903672	positive regulation of sprouting angiogenesis	6/2053	28/18722	0.0790355303015059	0.205020830872908	HMGB1/KLF4/VEGFA/ITGA5/JAK1/TJP1	6
GO:0006612	protein targeting to membrane	20/2053	131/18722	0.0793215121996594	0.205673756783905	ITGB2/NCF1/ITGAM/TCAF1/HSPA5/ZDHHC12/HRAS/CHP1/CIB1/PARD3/MYO1C/SDCBP/ANK3/RAB3IP/ICMT/SEC63/FIS1/SGTB/SIL1/NACA	20
GO:0032233	positive regulation of actin filament bundle assembly	11/2053	63/18722	0.0795539791428788	0.206187418944826	PLEK/FLNA/GPR65/ID1/CCDC88A/S100A10/NRP1/RHOA/RGCC/FERMT2/PFN1	11
GO:0033138	positive regulation of peptidyl-serine phosphorylation	17/2053	108/18722	0.0800373344743873	0.207350607446599	CD44/TGFB1/EGFR/VEGFA/TNF/APP/ARRB2/HSP90AA1/HSP90AB1/CAMK1/TXN/HCLS1/PARK7/TFRC/STK4/AKAP9/EIF4G1	17
GO:0045132	meiotic chromosome segregation	15/2053	93/18722	0.0812988755235643	0.210054840221526	TOP2A/SMC2/CCNE1/SMC4/RAD51C/ACTR2/RAD21/CCNE2/NUF2/FANCD2/PSMC3IP/ACTR3/TTK/TOP2B/BUB1B	15
GO:0097306	cellular response to alcohol	15/2053	93/18722	0.0812988755235643	0.210054840221526	CYBB/SPI1/KLF4/SOD2/KLF2/CDH1/PTGER4/DAG1/ATP2B1/RAD51/BRCA1/KCNMB1/BLM/CDK4/GNAI1	15
GO:0043470	regulation of carbohydrate catabolic process	10/2053	56/18722	0.0813795404772316	0.210054840221526	HMGB1/FBP1/APP/P2RX7/DDIT4/SLC2A6/STAT3/ARL2/INSR/PRKAG2	10
GO:0045599	negative regulation of fat cell differentiation	10/2053	56/18722	0.0813795404772316	0.210054840221526	TGFB1/ZFP36L2/TNF/JDP2/GATA3/YAP1/ANKRD26/FERMT2/E2F1/ASXL1	10
GO:0046456	icosanoid biosynthetic process	10/2053	56/18722	0.0813795404772316	0.210054840221526	CD74/ALOX5AP/MGST3/ALOX5/IL1B/SYK/TBXAS1/FABP5/LTA4H/PTGES	10
GO:0048255	mRNA stabilization	10/2053	56/18722	0.0813795404772316	0.210054840221526	SLC11A1/ZFP36/FUS/PABPC1/HNRNPD/MYD88/HNRNPA0/E2F1/YBX1/MAPK14	10
GO:1990089	response to nerve growth factor	10/2053	56/18722	0.0813795404772316	0.210054840221526	CORO1A/APP/ARPC3/HSPA5/ID1/CIB1/RAP1A/DYNC1LI2/PTN/E2F1	10
GO:0009064	glutamine family amino acid metabolic process	13/2053	78/18722	0.0813962505858413	0.210054840221526	SLC7A7/GLUL/DDAH2/OAT/GCLM/GMPS/ASS1/PYCR2/NIT2/RIMKLB/ASNSD1/GFPT1/PPAT	13
GO:0032024	positive regulation of insulin secretion	13/2053	78/18722	0.0813962505858413	0.210054840221526	HLA-DRB1/JAK2/GLUL/MPC2/SERP1/GJA1/TRPM2/ISL1/SOX4/ACSL4/PHPT1/BAD/TM7SF3	13
GO:0008286	insulin receptor signaling pathway	18/2053	116/18722	0.0817513311615679	0.210789852586767	SORL1/IL1B/SOCS3/NUCKS1/PDK4/PRKCB/KANK1/GNAI2/CCND3/SMARCC1/CDK4/GRB2/FOXO4/RHOQ/BCAR1/IGF1R/GAB1/INSR	18
GO:0018107	peptidyl-threonine phosphorylation	18/2053	116/18722	0.0817513311615679	0.210789852586767	TGFB1/LRRK2/APP/PRKDC/CDK1/BMP7/VRK1/PRKCB/DDIT4/CAMK2D/CHEK1/SPHK1/CALM2/PARD3/TTK/PKN1/EIF4G1/PRKAG2	18
GO:0006084	acetyl-CoA metabolic process	7/2053	35/18722	0.0821558077680896	0.211016629541326	KYNU/MPC2/ACSS1/PDK4/NUDT8/PMVK/PDHA1	7
GO:0006691	leukotriene metabolic process	7/2053	35/18722	0.0821558077680896	0.211016629541326	TLR2/ALOX5AP/MGST3/ALOX5/SYK/LTA4H/DPEP2	7
GO:0008608	attachment of spindle microtubules to kinetochore	7/2053	35/18722	0.0821558077680896	0.211016629541326	CDT1/NUF2/BUB3/NDC80/EML4/ECT2/AURKB	7
GO:0032232	negative regulation of actin filament bundle assembly	7/2053	35/18722	0.0821558077680896	0.211016629541326	WAS/STMN1/MET/TACSTD2/TJP1/WASF2/PFN1	7
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	7/2053	35/18722	0.0821558077680896	0.211016629541326	HSP90AB1/PBK/SMARCC1/SDCBP/USP14/SVIP/PARK7	7
GO:0033280	response to vitamin D	7/2053	35/18722	0.0821558077680896	0.211016629541326	SPP1/CXCL10/BMP7/ATP2B1/VDR/TRIM24/PTN	7
GO:0045907	positive regulation of vasoconstriction	7/2053	35/18722	0.0821558077680896	0.211016629541326	EGFR/TBXAS1/ICAM1/GJA1/HRH2/GJA5/RHOA	7
GO:0060236	regulation of mitotic spindle organization	7/2053	35/18722	0.0821558077680896	0.211016629541326	TPX2/TPR/GNAI1/HSPA1A/CHMP4C/GPSM2/DRG1	7
GO:0072528	pyrimidine-containing compound biosynthetic process	7/2053	35/18722	0.0821558077680896	0.211016629541326	DUT/UPP1/TYMS/DTYMK/UMPS/NME4/NME1	7
GO:0006692	prostanoid metabolic process	9/2053	49/18722	0.0826595287089332	0.211766512490862	CD74/IL1B/GSTP1/TBXAS1/HPGD/AKR1B1/FABP5/ATP6V1B1/PTGES	9
GO:0006693	prostaglandin metabolic process	9/2053	49/18722	0.0826595287089332	0.211766512490862	CD74/IL1B/GSTP1/TBXAS1/HPGD/AKR1B1/FABP5/ATP6V1B1/PTGES	9
GO:0038084	vascular endothelial growth factor signaling pathway	9/2053	49/18722	0.0826595287089332	0.211766512490862	VEGFA/NRP2/SEMA6A/FLT1/NRP1/MYO1C/CD63/GAB1/FOXC1	9
GO:0043457	regulation of cellular respiration	9/2053	49/18722	0.0826595287089332	0.211766512490862	UQCC2/CISD1/RHOA/ARL2/COX7A2/PARK7/BNIP3/VCP/TRAP1	9
GO:0046580	negative regulation of Ras protein signal transduction	9/2053	49/18722	0.0826595287089332	0.211766512490862	STMN1/FBP1/MET/TIMP2/ITGB1/BCL6/RASA1/KANK1/CCDC125	9
GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	9/2053	49/18722	0.0826595287089332	0.211766512490862	JAK2/TNF/DNMT1/GJA1/ADAMTS1/GNAI2/HPGD/JUN/LDLRAP1	9
GO:0006941	striated muscle contraction	26/2053	179/18722	0.082868385368489	0.212210974055029	CXCR4/FLNA/SLC8A1/DSP/RCSD1/C12orf57/KCNQ1/TNNI2/NR4A1/DSG2/GJA1/CAMK2D/KCNE3/ALDOA/GJA5/DSC2/CALM2/RGS2/SLC9A1/DLG1/DMD/GAA/CHRNB1/AKAP9/SMAD5/HOMER1	26
GO:0016601	Rac protein signal transduction	8/2053	42/18722	0.0830841414031502	0.212310412444166	AIF1/RAC2/HACD3/WASF2/RHOG/EPS8/GABARAP/DYNLT1	8
GO:0046688	response to copper ion	8/2053	42/18722	0.0830841414031502	0.212310412444166	APP/SOD1/MT1X/CDK1/ICAM1/MT2A/SOD3/PARK7	8
GO:0051602	response to electrical stimulus	8/2053	42/18722	0.0830841414031502	0.212310412444166	AIF1/CD14/SOD2/NR4A1/BTG2/HNRNPD/SLC9A1/AKAP9	8
GO:0071312	cellular response to alkaloid	8/2053	42/18722	0.0830841414031502	0.212310412444166	AIF1/SLC8A1/TGM2/RAD51/ICAM1/CCNA2/BLM/SLC1A3	8
GO:2001222	regulation of neuron migration	8/2053	42/18722	0.0830841414031502	0.212310412444166	FLNA/PHACTR1/ADGRG1/SEMA6A/STAT3/KIF20B/ARHGEF2/MDK	8
GO:0010508	positive regulation of autophagy	19/2053	124/18722	0.0831577084759154	0.212407939912939	MTDH/TRIM22/HMGB1/LRRK2/HMOX1/PLK3/SLC25A5/BNIP3L/PHB2/SLC25A4/RALB/SVIP/TRIM38/VDAC1/SCOC/PARK7/BAD/BNIP3/PLK2	19
GO:0006959	humoral immune response	43/2053	317/18722	0.0832050205016403	0.212438350216954	HLA-A/LYZ/PTPRC/HLA-DRB1/FCN1/SLC11A1/HLA-DQB1/HLA-E/MEF2C/CD83/CFD/POU2F2/S100A12/CFP/ALOX5/TNF/TREM1/IL1B/CCR2/RNASE6/CXCL10/C3/CD46/PTPN6/S100A9/NOTCH1/TREM2/C1QA/CD59/GPR183/HMGN2/CXCL8/RPS19/C1QBP/NOTCH2/RGCC/GATA3/PHB/PSMB10/DEFB1/EXO1/SERPING1/GAPDH	43
GO:0150115	cell-substrate junction organization	16/2053	101/18722	0.0836593015815781	0.213507362607175	FN1/VEGFA/ITGA6/ITGB4/PTK2B/LAMC1/S100A10/LIMS1/NRP1/RHOA/FERMT2/SLC9A1/VCL/CORO1C/PTK2/TRIP6	16
GO:0003208	cardiac ventricle morphogenesis	12/2053	71/18722	0.0842798860590663	0.214725824354309	TGFB1/MEF2C/LRP2/DSP/ENG/NOTCH1/ISL1/SOX4/GATA3/FKBP1A/FOXC1/TGFBR3	12
GO:0033555	multicellular organismal response to stress	12/2053	71/18722	0.0842798860590663	0.214725824354309	TSPO/MEF2C/NR4A2/VWA1/DPP4/COMT/GJA1/ADRB1/VDAC1/GCH1/MDK/EIF4G1	12
GO:0071230	cellular response to amino acid stimulus	12/2053	71/18722	0.0842798860590663	0.214725824354309	CYBB/CYBA/TNF/CEBPB/DNMT1/LAMTOR4/HNRNPD/GCLM/ASS1/COL4A1/IPO5/SLC38A9	12
GO:0072078	nephron tubule morphogenesis	12/2053	71/18722	0.0842798860590663	0.214725824354309	VEGFA/MAGED1/LAMA5/TACSTD2/AHI1/GATA3/PBX1/LGR4/DLG1/GLI3/IRX2/GPC3	12
GO:0014031	mesenchymal cell development	14/2053	86/18722	0.0846964972542288	0.215695663635557	FN1/NRP2/BMP7/LAMA5/SEMA4A/NOTCH1/SEMA6A/NRP1/ISL1/FOLR1/SEMA6D/TCOF1/CORO1C/FOXC1	14
GO:0030177	positive regulation of Wnt signaling pathway	21/2053	140/18722	0.085208864454306	0.216339747196961	ZEB2/TGFB1/TLR2/EGFR/LRRK2/TNFAIP3/WLS/HHEX/RPS12/LGR5/ASPM/KANK1/ATP6V1C2/SULF2/SOX4/LGR4/YAP1/TBL1X/VCP/MBD2/GPC3	21
GO:0002320	lymphoid progenitor cell differentiation	5/2053	22/18722	0.085382086893734	0.216339747196961	SPI1/PRKDC/NOTCH1/SOX4/GATA3	5
GO:0033617	mitochondrial cytochrome c oxidase assembly	5/2053	22/18722	0.085382086893734	0.216339747196961	SCO2/COX20/COA4/SCO1/COX17	5
GO:0034629	cellular protein-containing complex localization	5/2053	22/18722	0.085382086893734	0.216339747196961	TNFAIP2/RALB/EZR/DLG1/AKAP9	5
GO:0035561	regulation of chromatin binding	5/2053	22/18722	0.085382086893734	0.216339747196961	GMNN/PARP9/CDT1/DTX3L/MBD2	5
GO:0036120	cellular response to platelet-derived growth factor stimulus	5/2053	22/18722	0.085382086893734	0.216339747196961	TLR4/RDX/CCNA2/YES1/PTN	5
GO:0045061	thymic T cell selection	5/2053	22/18722	0.085382086893734	0.216339747196961	PTPRC/CD74/DOCK2/GATA3/GLI3	5
GO:0045624	positive regulation of T-helper cell differentiation	5/2053	22/18722	0.085382086893734	0.216339747196961	CD86/NLRP3/RARA/NFKBIZ/IL18	5
GO:0051220	cytoplasmic sequestering of protein	5/2053	22/18722	0.085382086893734	0.216339747196961	TMSB4X/FLNA/NFKBIA/NFKBIE/GOPC	5
GO:0051412	response to corticosterone	5/2053	22/18722	0.085382086893734	0.216339747196961	FOS/ATP2B1/CCND1/FOSB/CDKN1A	5
GO:0071359	cellular response to dsRNA	5/2053	22/18722	0.085382086893734	0.216339747196961	IFIT1/COLEC12/NPM1/RALB/DDX58	5
GO:1901032	negative regulation of response to reactive oxygen species	5/2053	22/18722	0.085382086893734	0.216339747196961	LRRK2/MET/TXN/PARK7/TRAP1	5
GO:0009749	response to glucose	30/2053	212/18722	0.0867990353512765	0.21923866476057	TXNIP/HLA-DRB1/LGALS1/CYBA/SLC8A1/UCP2/SERPINF1/GLUL/MPC2/TREM2/PTK2B/ICAM1/CTSV/SLC29A1/GJA1/HMGN3/KLF7/LDHA/RHOA/SOX4/GCLM/LRP5/FIS1/PHPT1/BAD/IGF1R/TRA2B/ENSA/NME1/CCDC186	30
GO:2000058	regulation of ubiquitin-dependent protein catabolic process	24/2053	164/18722	0.086835869678075	0.21923866476057	LAPTM5/LRRK2/RPS7/PLK3/HSP90AB1/RPL5/RPL23/PTK2B/PBK/TRIB1/SMARCC1/SDCBP/USP14/SVIP/MAGEF1/PARK7/COMMD1/RAD23B/HSPA1A/CDK2/VCP/PLK2/GABARAP/PTK2	24
GO:0001820	serotonin secretion	3/2053	10/18722	0.0877320056816882	0.21923866476057	LILRB1/SYK/SLC6A4	3
GO:0001915	negative regulation of T cell mediated cytotoxicity	3/2053	10/18722	0.0877320056816882	0.21923866476057	PTPRC/NCKAP1L/LILRB1	3
GO:0002002	regulation of angiotensin levels in blood	3/2053	10/18722	0.0877320056816882	0.21923866476057	CTSZ/MME/ENPEP	3
GO:0002003	angiotensin maturation	3/2053	10/18722	0.0877320056816882	0.21923866476057	CTSZ/MME/ENPEP	3
GO:0002934	desmosome organization	3/2053	10/18722	0.0877320056816882	0.21923866476057	PERP/DSP/DSG2	3
GO:0003056	regulation of vascular associated smooth muscle contraction	3/2053	10/18722	0.0877320056816882	0.21923866476057	DOCK4/ATP2B1/RHOA	3
GO:0003183	mitral valve morphogenesis	3/2053	10/18722	0.0877320056816882	0.21923866476057	NOTCH1/SOX4/EFNA1	3
GO:0003330	regulation of extracellular matrix constituent secretion	3/2053	10/18722	0.0877320056816882	0.21923866476057	TNFRSF1B/NOTCH1/RGCC	3
GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation	3/2053	10/18722	0.0877320056816882	0.21923866476057	NPM1/EIF2AK4/EIF2AK1	3
GO:0021932	hindbrain radial glia guided cell migration	3/2053	10/18722	0.0877320056816882	0.21923866476057	FLNA/ITGB1/RERE	3
GO:0032025	response to cobalt ion	3/2053	10/18722	0.0877320056816882	0.21923866476057	SERPINF1/BNIP3/ALAD	3
GO:0035520	monoubiquitinated protein deubiquitination	3/2053	10/18722	0.0877320056816882	0.21923866476057	USP1/USP15/ASXL1	3
GO:0044351	macropinocytosis	3/2053	10/18722	0.0877320056816882	0.21923866476057	PYCARD/DOCK2/MAPKAPK3	3
GO:0044557	relaxation of smooth muscle	3/2053	10/18722	0.0877320056816882	0.21923866476057	SLC8A1/SOD1/RGS2	3
GO:0045348	positive regulation of MHC class II biosynthetic process	3/2053	10/18722	0.0877320056816882	0.21923866476057	JAK2/TLR4/CIITA	3
GO:0051351	positive regulation of ligase activity	3/2053	10/18722	0.0877320056816882	0.21923866476057	TMSB4X/GCLM/MID1IP1	3
GO:0051409	response to nitrosative stress	3/2053	10/18722	0.0877320056816882	0.21923866476057	ADH5/GCLM/PARK7	3
GO:0061299	retina vasculature morphogenesis in camera-type eye	3/2053	10/18722	0.0877320056816882	0.21923866476057	NRP1/LRP5/COL4A1	3
GO:0070383	DNA cytosine deamination	3/2053	10/18722	0.0877320056816882	0.21923866476057	APOBEC3A/APOBEC3G/APOBEC3C	3
GO:0072178	nephric duct morphogenesis	3/2053	10/18722	0.0877320056816882	0.21923866476057	AHI1/GATA3/GPC3	3
GO:0072203	cell proliferation involved in metanephros development	3/2053	10/18722	0.0877320056816882	0.21923866476057	STAT1/BMP7/GPC3	3
GO:0097084	vascular associated smooth muscle cell development	3/2053	10/18722	0.0877320056816882	0.21923866476057	VEGFA/ENG/NOTCH1	3
GO:0097278	complement-dependent cytotoxicity	3/2053	10/18722	0.0877320056816882	0.21923866476057	C3/HSP90AB1/CD59	3
GO:0098885	modification of postsynaptic actin cytoskeleton	3/2053	10/18722	0.0877320056816882	0.21923866476057	MYH10/RHOA/PFN1	3
GO:0099532	synaptic vesicle endosomal processing	3/2053	10/18722	0.0877320056816882	0.21923866476057	ITSN2/EEA1/STX6	3
GO:1901203	positive regulation of extracellular matrix assembly	3/2053	10/18722	0.0877320056816882	0.21923866476057	TGFB1/DAG1/RGCC	3
GO:1901725	regulation of histone deacetylase activity	3/2053	10/18722	0.0877320056816882	0.21923866476057	LRRK2/VEGFA/CAMK2D	3
GO:1901978	positive regulation of cell cycle checkpoint	3/2053	10/18722	0.0877320056816882	0.21923866476057	MAD2L1/TPR/NDC80	3
GO:1903867	extraembryonic membrane development	3/2053	10/18722	0.0877320056816882	0.21923866476057	BMP7/MAP3K4/E2F7	3
GO:1903980	positive regulation of microglial cell activation	3/2053	10/18722	0.0877320056816882	0.21923866476057	CCL3/LRRK2/TREM2	3
GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin	3/2053	10/18722	0.0877320056816882	0.21923866476057	VEGFA/NOTCH1/RGCC	3
GO:0006446	regulation of translational initiation	13/2053	79/18722	0.0881281238884608	0.220045253154709	TNF/EIF1/NPM1/RPL13A/TPR/EIF5B/EIF2AK4/DDX1/EIF2AK1/EIF5/PPP1R15A/AGO2/EIF4G1	13
GO:0060420	regulation of heart growth	13/2053	79/18722	0.0881281238884608	0.220045253154709	MEF2C/DUSP9/RUNX1/CDK1/NOTCH1/HAMP/GJA1/YAP1/PARP2/RGS2/TGFBR3/BASP1/MAPK14	13
GO:0018210	peptidyl-threonine modification	19/2053	125/18722	0.0884616927670827	0.22069445180977	TGFB1/LRRK2/APP/PRKDC/CDK1/BMP7/GALNT11/VRK1/PRKCB/DDIT4/CAMK2D/CHEK1/SPHK1/CALM2/PARD3/TTK/PKN1/EIF4G1/PRKAG2	19
GO:0051053	negative regulation of DNA metabolic process	19/2053	125/18722	0.0884616927670827	0.22069445180977	DUSP1/PARP1/RPS3/BCL6/RMI2/HNRNPA1/GJA1/MSH2/MSH6/BLM/GATA3/XRCC5/RAD50/MAGEF1/ERCC1/CDKN1A/RIF1/POLQ/TRIM28	19
GO:0010595	positive regulation of endothelial cell migration	20/2053	133/18722	0.0894764050247577	0.220898643490314	TMSB4X/TGFB1/HMGB1/VEGFA/HMOX1/GRN/MET/NRP2/CALR/PTK2B/STAT5A/RRAS/NRP1/CIB1/GATA3/PLPP3/ANXA3/BCAR1/RHOB/PLK2	20
GO:0030219	megakaryocyte differentiation	10/2053	57/18722	0.0894767175250079	0.220898643490314	MEF2C/HMGB2/PTPN6/FLI1/SH2B3/CIB1/SCIN/PITHD1/WASF2/RCOR1	10
GO:0001841	neural tube formation	16/2053	102/18722	0.0896146098773106	0.220898643490314	TGFB1/SPINT1/SPINT2/LRP2/VASP/RPS7/RARA/BMP7/LMO4/SOX4/FOLR1/KIF20B/PFN1/LUZP1/STK4/COBL	16
GO:0007204	positive regulation of cytosolic calcium ion concentration	43/2053	319/18722	0.0897383908838406	0.220898643490314	PTPRC/CXCR4/CD52/CORO1A/CCL3/CYBA/FPR1/C5AR1/LYN/FPR3/SLC8A1/C3AR1/GPR65/HMGB1/JAK2/LPAR6/CCR1/CD36/CCR2/PTGER4/CXCL10/CD24/S1PR4/TGM2/PTPN6/CCRL2/PTK2B/TRPV2/P2RX7/GNA15/CYSLTR1/GJA1/CX3CR1/CAMK2D/TRPM2/CALM2/MCOLN3/ITGAV/FIS1/DMD/FKBP1A/C1QTNF1/UBASH3B	43
GO:0001732	formation of cytoplasmic translation initiation complex	4/2053	16/18722	0.0897584821382311	0.220898643490314	EIF5/EIF3J/EIF3A/EIF3L	4
GO:0001977	renal system process involved in regulation of blood volume	4/2053	16/18722	0.0897584821382311	0.220898643490314	CYBA/EMP2/GJA1/GJA5	4
GO:0002921	negative regulation of humoral immune response	4/2053	16/18722	0.0897584821382311	0.220898643490314	CD46/PTPN6/CD59/SERPING1	4
GO:0006544	glycine metabolic process	4/2053	16/18722	0.0897584821382311	0.220898643490314	GCSH/DHFR/GLDC/SHMT1	4
GO:0006857	oligopeptide transport	4/2053	16/18722	0.0897584821382311	0.220898643490314	GJA1/SLC15A3/MGST1/SLC13A3	4
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	4/2053	16/18722	0.0897584821382311	0.220898643490314	BRCA2/SP100/CDKN1A/FOXM1	4
GO:0010225	response to UV-C	4/2053	16/18722	0.0897584821382311	0.220898643490314	CARD16/BRCA2/HMGN1/MAP3K4	4
GO:0019081	viral translation	4/2053	16/18722	0.0897584821382311	0.220898643490314	EIF2AK4/DENR/EIF3A/EIF3L	4
GO:0034116	positive regulation of heterotypic cell-cell adhesion	4/2053	16/18722	0.0897584821382311	0.220898643490314	CD44/TNF/IL1B/BMP7	4
GO:0034393	positive regulation of smooth muscle cell apoptotic process	4/2053	16/18722	0.0897584821382311	0.220898643490314	SOD2/CDKN2A/STK4/PPARG	4
GO:0035067	negative regulation of histone acetylation	4/2053	16/18722	0.0897584821382311	0.220898643490314	SPI1/BRCA1/SET/ZNF451	4
GO:0035970	peptidyl-threonine dephosphorylation	4/2053	16/18722	0.0897584821382311	0.220898643490314	DUSP1/PPM1G/DUSP18/DUSP5	4
GO:0045651	positive regulation of macrophage differentiation	4/2053	16/18722	0.0897584821382311	0.220898643490314	TGFB1/TRIB1/HCLS1/ID2	4
GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	4/2053	16/18722	0.0897584821382311	0.220898643490314	APOBEC3A/APOBEC3G/APOBEC3C/TRIM28	4
GO:0046037	GMP metabolic process	4/2053	16/18722	0.0897584821382311	0.220898643490314	GMPS/IMPDH2/DLG1/MPP1	4
GO:0048385	regulation of retinoic acid receptor signaling pathway	4/2053	16/18722	0.0897584821382311	0.220898643490314	KLF2/CALR/EZH2/ASXL1	4
GO:0050884	neuromuscular process controlling posture	4/2053	16/18722	0.0897584821382311	0.220898643490314	PNKD/TMEM150C/GCH1/GAA	4
GO:0051238	sequestering of metal ion	4/2053	16/18722	0.0897584821382311	0.220898643490314	S100A8/FTH1/FTL/S100A9	4
GO:0061684	chaperone-mediated autophagy	4/2053	16/18722	0.0897584821382311	0.220898643490314	PLK3/HSP90AA1/HSPA8/SNRNP70	4
GO:0071361	cellular response to ethanol	4/2053	16/18722	0.0897584821382311	0.220898643490314	CYBB/SPI1/SOD2/KCNMB1	4
GO:0071732	cellular response to nitric oxide	4/2053	16/18722	0.0897584821382311	0.220898643490314	CCNA2/HNRNPD/CDK2/MTR	4
GO:0097428	protein maturation by iron-sulfur cluster transfer	4/2053	16/18722	0.0897584821382311	0.220898643490314	GLRX5/MAGEF1/CIAO1/ISCA1	4
GO:0099010	modification of postsynaptic structure	4/2053	16/18722	0.0897584821382311	0.220898643490314	MYH10/STAU1/RHOA/PFN1	4
GO:0099633	protein localization to postsynaptic specialization membrane	4/2053	16/18722	0.0897584821382311	0.220898643490314	DAG1/HRAS/RAP1A/DLG1	4
GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	4/2053	16/18722	0.0897584821382311	0.220898643490314	DAG1/HRAS/RAP1A/DLG1	4
GO:1901201	regulation of extracellular matrix assembly	4/2053	16/18722	0.0897584821382311	0.220898643490314	TGFB1/DAG1/NOTCH1/RGCC	4
GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	4/2053	16/18722	0.0897584821382311	0.220898643490314	CD74/CD44/TRIAP1/ING2	4
GO:1905906	regulation of amyloid fibril formation	4/2053	16/18722	0.0897584821382311	0.220898643490314	APP/PFDN5/TREM2/PFDN1	4
GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	4/2053	16/18722	0.0897584821382311	0.220898643490314	LGALS9/PLAUR/JAK2/PARK7	4
GO:0016055	Wnt signaling pathway	58/2053	444/18722	0.0900361871016333	0.22149123518237	ZEB2/TGFB1/TLR2/KLF4/EGFR/LRRK2/TNFAIP3/NR4A2/APP/WLS/CD24/PFDN5/NOTCH1/HHEX/RPS12/NOTUM/CCND1/RNF43/CCNE1/LGR5/RTF1/ASPM/KANK1/TPBG/FERMT1/ATP6V1C2/RNF213/DDB1/SULF2/ISL1/RHOA/SIAH2/SOX4/BRD7/GATA3/FOLR1/LRP5/PLPP3/LGR4/YAP1/FERMT2/HMGXB4/TLE1/TBL1X/GLI3/STK4/VCP/MDK/CTNND1/MBD2/ZNRF3/DAAM1/AMOTL2/PTPRU/MAPK14/AMOTL1/RAC3/GPC3	58
GO:0022898	regulation of transmembrane transporter activity	38/2053	278/18722	0.090266879215944	0.221967735776911	CTSS/TMSB4X/FXYD5/MEF2C/ACTB/TCAF1/APP/PTAFR/FXYD3/CCR2/GLRX/IFNGR2/ITGB1/TREM2/KCNQ1/PTK2B/VMP1/PHB2/GJA1/CAMK2D/KCNE3/CHP1/CALM2/C4orf3/ANK3/GOPC/YWHAE/SLC9A1/PARK7/DLG1/DMD/FKBP1A/PTPN3/AKAP9/CAPN1/HOMER1/ACTN4/COX17	38
GO:0009310	amine catabolic process	6/2053	29/18722	0.0908429664490702	0.222563413105113	KYNU/SAT1/IL4I1/ALDH7A1/COMT/SLC44A1	6
GO:0022011	myelination in peripheral nervous system	6/2053	29/18722	0.0908429664490702	0.222563413105113	DAG1/SOD1/ITGB4/PARD3/ADGRG6/NDRG1	6
GO:0032292	peripheral nervous system axon ensheathment	6/2053	29/18722	0.0908429664490702	0.222563413105113	DAG1/SOD1/ITGB4/PARD3/ADGRG6/NDRG1	6
GO:0033028	myeloid cell apoptotic process	6/2053	29/18722	0.0908429664490702	0.222563413105113	MEF2C/CTSL/IRF7/PLEKHO2/TCP1/CDKN2A	6
GO:0035066	positive regulation of histone acetylation	6/2053	29/18722	0.0908429664490702	0.222563413105113	IL1B/BRCA1/ISL1/BRD7/GATA3/RPS6KA5	6
GO:0048679	regulation of axon regeneration	6/2053	29/18722	0.0908429664490702	0.222563413105113	FLNA/KLF4/SPP1/GRN/PTPRF/PTN	6
GO:0060441	epithelial tube branching involved in lung morphogenesis	6/2053	29/18722	0.0908429664490702	0.222563413105113	TNF/CTSH/CTSZ/DAG1/DLG5/YAP1	6
GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	6/2053	29/18722	0.0908429664490702	0.222563413105113	CD74/CD44/RPS7/UBB/TRIAP1/ING2	6
GO:2001032	regulation of double-strand break repair via nonhomologous end joining	6/2053	29/18722	0.0908429664490702	0.222563413105113	DEK/PRKDC/PARP9/PNKP/DTX3L/RIF1	6
GO:0030032	lamellipodium assembly	12/2053	72/18722	0.091547977598733	0.224199128813224	WAS/RAC2/ABI3/ITGB1/SPATA13/CCDC88A/ACTR2/TWF2/ACTR3/WASF2/VCL/VAV3	12
GO:0031346	positive regulation of cell projection organization	47/2053	353/18722	0.0925978748934595	0.226593032090908	FLNA/LYN/FN1/RAC2/SKIL/VEGFA/ITGA6/PLXNC1/SERPINF1/GRN/CAMK1D/CAMK1/TENM3/BMP7/S100A9/PTK2B/HSPA5/TRPV2/P2RX7/EZH2/CCDC88A/HRAS/NRP1/ACTR2/GOLGA4/TWF2/ANLN/RAP1A/ACTR3/FNBP1L/WASF2/PFN1/OBSL1/RGS2/EPS8/RHOQ/CORO1C/EPS8L2/ATMIN/DOCK11/MDK/NME1/P3H1/PTN/CCP110/COBL/DYNLT1	47
GO:0009268	response to pH	8/2053	43/18722	0.0927520811358782	0.226593032090908	CTSS/GPR65/SERPINF1/HVCN1/GJA1/CHP1/GNA11/SLC9A1	8
GO:0033173	calcineurin-NFAT signaling cascade	8/2053	43/18722	0.0927520811358782	0.226593032090908	CLEC7A/TNF/HOMER3/CHP1/CIB1/SLC9A1/FHL2/NFAT5	8
GO:0035794	positive regulation of mitochondrial membrane permeability	8/2053	43/18722	0.0927520811358782	0.226593032090908	SLC25A5/BNIP3L/HEBP2/CHCHD10/SLC9A1/HSPA1A/NMT1/BNIP3	8
GO:0045840	positive regulation of mitotic nuclear division	8/2053	43/18722	0.0927520811358782	0.226593032090908	IL1B/NUSAP1/ANAPC11/CDT1/SPHK1/RGCC/LRP5/INSR	8
GO:0060443	mammary gland morphogenesis	8/2053	43/18722	0.0927520811358782	0.226593032090908	CSF1R/STAT6/PHB2/VDR/LRP5/GLI3/TBX3/CAPN1	8
GO:0034329	cell junction assembly	55/2053	420/18722	0.0933765114374833	0.228025668956003	PECAM1/MTDH/CD9/MEF2C/TLR2/FN1/ACTB/ABI3/VEGFA/ITGA6/CDH1/TNF/IL1B/APP/GPBAR1/CLDN4/SEMA4A/ITGB4/CLDN7/PTK2B/LAMC1/ZDHHC12/VMP1/GJA1/LSR/TPBG/CNTNAP2/S100A10/LIMS1/GJA5/NRP1/RHOA/MARVELD3/PARD3/ARL2/DLG5/MYO1C/SDCBP/JAM3/TJP1/RAP1A/FERMT2/OBSL1/SLC9A1/VCL/ECT2/CORO1C/PARD6B/DLG1/CTNND1/PTK2/TRIP6/EIF4G1/CLSTN1/MPP7	55
GO:0006942	regulation of striated muscle contraction	15/2053	95/18722	0.0937922810575922	0.228854691478468	SLC8A1/DSP/C12orf57/KCNQ1/NR4A1/DSG2/CAMK2D/GJA5/DSC2/CALM2/RGS2/SLC9A1/DLG1/DMD/AKAP9	15
GO:0048709	oligodendrocyte differentiation	15/2053	95/18722	0.0937922810575922	0.228854691478468	CXCR4/TNFRSF1B/LYN/CD9/TLR2/GSTP1/DAG1/CSK/NOTCH1/RHEB/HDAC2/BNIP3/GLI3/MDK/PTN	15
GO:0032874	positive regulation of stress-activated MAPK cascade	19/2053	126/18722	0.0939802376016307	0.229220091711294	NCF1/SPI1/CLEC7A/PYCARD/SCIMP/HMGB1/VEGFA/TNF/TLR4/IL1B/APP/GADD45B/PTK2B/HRAS/SPHK1/SDCBP/MYD88/RASSF2/MAP3K4	19
GO:0048863	stem cell differentiation	29/2053	206/18722	0.0955484174767138	0.23295022546131	PTPRC/ZFP36L2/MEF2C/FN1/PRKDC/NRP2/KRT18/BMP7/LAMA5/SEMA4A/NOTCH1/SEMA6A/TACSTD2/MSI2/NRP1/ISL1/PSMD11/STAT3/FOLR1/SEMA6D/TCOF1/XRCC5/YAP1/FOXO4/CORO1C/FOXC1/PTN/HSPA9/PWP1	29
GO:0019395	fatty acid oxidation	16/2053	103/18722	0.0958328658014495	0.233369596739727	SLC27A2/ECI1/ECHS1/PDK4/ADH5/ACADVL/ECHDC2/ETFB/HADH/ETFA/ACAT2/ECI2/SLC25A17/ECH1/MAPK14/PRKAG2	16
GO:0046425	regulation of receptor signaling pathway via JAK-STAT	16/2053	103/18722	0.0958328658014495	0.233369596739727	PTPRC/IL10RA/CD300A/JAK2/TNF/SOCS3/NOTCH1/IL6R/PTK2B/SH2B3/AKR1B1/SUZ12/CSH1/PARP14/CENPJ/PWP1	16
GO:0198738	cell-cell signaling by wnt	58/2053	446/18722	0.0958371143944477	0.233369596739727	ZEB2/TGFB1/TLR2/KLF4/EGFR/LRRK2/TNFAIP3/NR4A2/APP/WLS/CD24/PFDN5/NOTCH1/HHEX/RPS12/NOTUM/CCND1/RNF43/CCNE1/LGR5/RTF1/ASPM/KANK1/TPBG/FERMT1/ATP6V1C2/RNF213/DDB1/SULF2/ISL1/RHOA/SIAH2/SOX4/BRD7/GATA3/FOLR1/LRP5/PLPP3/LGR4/YAP1/FERMT2/HMGXB4/TLE1/TBL1X/GLI3/STK4/VCP/MDK/CTNND1/MBD2/ZNRF3/DAAM1/AMOTL2/PTPRU/MAPK14/AMOTL1/RAC3/GPC3	58
GO:0023061	signal release	60/2053	463/18722	0.0963478048119425	0.234517983315073	HLA-DRB1/LYN/MEF2C/LILRB1/EGFR/UCP2/SPP1/JAK2/LRRK2/RETN/ALOX5/TNF/IL1B/WLS/IL1RN/STXBP2/BTK/STX11/GLUL/SYK/MPC2/SERP1/DPP4/MCTP1/KCNQ1/NR4A1/PNKD/PRKCB/PPT1/GJA1/FAM3B/HMGN3/UQCC2/TRPM2/SLC6A4/KLF7/ISL1/SYT7/SOX4/HADH/GATA3/SNX4/ACSL4/SLC16A1/LRP5/RAP1A/CYB5R4/CAMK2G/PARK7/PHPT1/BAD/TCIRG1/PTGES/MIDN/C1QTNF1/ENSA/CHRNA5/TBX3/TM7SF3/CCDC186	60
GO:0018209	peptidyl-serine modification	45/2053	338/18722	0.0980337095864369	0.238056617620624	CD44/TGFB1/EGFR/LRRK2/VEGFA/TNF/PARP1/APP/SGK1/ARRB2/PRKDC/HSP90AA1/CLSPN/SYK/HSP90AB1/CAMK1D/CAMK1/CDK1/VRK1/PRKCB/DDIT4/CAMK2D/RPS6KA1/MAPKAPK3/TXN/PARP2/RASSF2/HCLS1/TTK/MASTL/PARK7/DMD/CDK2/AURKB/TLK1/TFRC/STK4/NTMT1/PLK2/AKAP9/RPS6KA5/PWP1/PKN1/EIF4G1/MAPK14	45
GO:0007131	reciprocal meiotic recombination	10/2053	58/18722	0.0980396503567603	0.238056617620624	TOP2A/RAD51AP1/RAD51/RAD51C/RAD21/MND1/FANCD2/RAD50/PSMC3IP/TOP2B	10
GO:0018208	peptidyl-proline modification	10/2053	58/18722	0.0980396503567603	0.238056617620624	P4HB/PRDX4/PPIA/PPIB/PPIC/FKBP5/FKBP3/FKBP1A/NTMT1/P3H1	10
GO:0086065	cell communication involved in cardiac conduction	10/2053	58/18722	0.0980396503567603	0.238056617620624	FLNA/SLC8A1/DSP/KCNQ1/DSG2/GJA1/CAMK2D/GJA5/DSC2/CALM2	10
GO:0140527	reciprocal homologous recombination	10/2053	58/18722	0.0980396503567603	0.238056617620624	TOP2A/RAD51AP1/RAD51/RAD51C/RAD21/MND1/FANCD2/RAD50/PSMC3IP/TOP2B	10
GO:2000736	regulation of stem cell differentiation	10/2053	58/18722	0.0980396503567603	0.238056617620624	ZFP36L2/PRKDC/NOTCH1/TACSTD2/STAT3/YAP1/FOXC1/PTN/HSPA9/PWP1	10
GO:0048638	regulation of developmental growth	44/2053	330/18722	0.0991071309799975	0.240266094562507	CXCR4/MEF2C/PLAC8/FN1/SPP1/VEGFA/DUSP9/APP/RUNX1/SASH3/PRKDC/SOD1/CDK1/SERP1/SEMA4A/NOTCH1/PPIB/ARHGAP4/HAMP/TRPV2/STAT5A/SEMA6A/GJA1/ITSN2/NRP1/SLC6A4/ADRB1/STAT3/GOLGA4/CDK4/TWF2/SEMA6D/YAP1/PARP2/AFG3L2/RGS2/EZR/CDKN1A/STK4/FOXC1/INSR/TGFBR3/BASP1/MAPK14	44
GO:0051298	centrosome duplication	12/2053	73/18722	0.099187878035183	0.240266094562507	NPM1/BRCA1/CEP152/BRCA2/NDC80/CDK2/CENPJ/SASS6/CHMP4C/PLK2/CCP110/SAC3D1	12
GO:0086003	cardiac muscle cell contraction	12/2053	73/18722	0.099187878035183	0.240266094562507	FLNA/DSP/KCNQ1/DSG2/GJA1/CAMK2D/KCNE3/GJA5/DSC2/SLC9A1/DLG1/AKAP9	12
GO:0002052	positive regulation of neuroblast proliferation	5/2053	23/18722	0.0997104292434406	0.240266094562507	VEGFA/NOTCH1/ASPM/CX3CR1/GLI3	5
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	5/2053	23/18722	0.0997104292434406	0.240266094562507	CYBA/CTSZ/MME/ENPEP/RHOA	5
GO:0016578	histone deubiquitination	5/2053	23/18722	0.0997104292434406	0.240266094562507	USP15/USP3/USP22/BRCC3/ASXL1	5
GO:0018279	protein N-linked glycosylation via asparagine	5/2053	23/18722	0.0997104292434406	0.240266094562507	RPN2/DDOST/TUSC3/FUT8/ALG8	5
GO:0032740	positive regulation of interleukin-17 production	5/2053	23/18722	0.0997104292434406	0.240266094562507	TGFB1/SPHK1/MYD88/PHB/IL18	5
GO:0035162	embryonic hemopoiesis	5/2053	23/18722	0.0997104292434406	0.240266094562507	VEGFA/SH2B3/GATA3/PBX1/STK4	5
GO:0036119	response to platelet-derived growth factor	5/2053	23/18722	0.0997104292434406	0.240266094562507	TLR4/RDX/CCNA2/YES1/PTN	5
GO:0036303	lymph vessel morphogenesis	5/2053	23/18722	0.0997104292434406	0.240266094562507	VEGFA/VASH1/SVEP1/PTPN14/FOXC1	5
GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	5/2053	23/18722	0.0997104292434406	0.240266094562507	CTSL/STAT6/IL6R/SPN/STAT3	5
GO:0045980	negative regulation of nucleotide metabolic process	5/2053	23/18722	0.0997104292434406	0.240266094562507	FBP1/PARP1/CDA/DDIT4/STAT3	5
GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	5/2053	23/18722	0.0997104292434406	0.240266094562507	TYROBP/CD53/CAMK1/TREM2/MAPK14	5
GO:0060575	intestinal epithelial cell differentiation	5/2053	23/18722	0.0997104292434406	0.240266094562507	TYMS/IL6ST/YAP1/KLF5/CDKN1A	5
GO:1900273	positive regulation of long-term synaptic potentiation	5/2053	23/18722	0.0997104292434406	0.240266094562507	APP/MME/STAU1/NRGN/EIF2AK4	5
GO:2000737	negative regulation of stem cell differentiation	5/2053	23/18722	0.0997104292434406	0.240266094562507	ZFP36L2/NOTCH1/STAT3/YAP1/HSPA9	5
GO:2000810	regulation of bicellular tight junction assembly	5/2053	23/18722	0.0997104292434406	0.240266094562507	TNF/GPBAR1/GJA1/MYO1C/TJP1	5
GO:2001169	regulation of ATP biosynthetic process	5/2053	23/18722	0.0997104292434406	0.240266094562507	TMSB4X/PARP1/TREM2/STAT3/VCP	5
GO:0001823	mesonephros development	15/2053	96/18722	0.100465169067264	0.241793427358036	VEGFA/MAGED1/RARA/BMP7/LAMA5/TACSTD2/GATA3/PBX1/LGR4/DLG1/GLI3/FOXC1/SMAD5/BASP1/GPC3	15
GO:1901655	cellular response to ketone	15/2053	96/18722	0.100465169067264	0.241793427358036	MSN/KLF4/EGFR/SPP1/KLF2/SERPINF1/PTGER4/ATP2B1/ICAM1/DDIT4/AKR1B1/CDK4/ASS1/GNAI1/PARK7	15
GO:1904035	regulation of epithelial cell apoptotic process	15/2053	96/18722	0.100465169067264	0.241793427358036	ZFP36/JAK2/TNF/TNFAIP3/ITGA4/HMOX1/ARRB2/ZFP36L1/ICAM1/RGCC/GATA3/YAP1/BAD/TIA1/MDK	15
GO:0021872	forebrain generation of neurons	9/2053	51/18722	0.100842684960478	0.242410300385764	B2M/NRP2/ASPM/UBB/UQCRQ/NRP1/ZSWIM6/RHOA/GLI3	9
GO:0051293	establishment of spindle localization	9/2053	51/18722	0.100842684960478	0.242410300385764	ITGB1/NUSAP1/MAD2L1/GJA1/KPNB1/NDC80/GPSM2/CFL1/DYNLT1	9
GO:1903307	positive regulation of regulated secretory pathway	9/2053	51/18722	0.100842684960478	0.242410300385764	ITGB2/HLA-F/FGR/ITGAM/PTAFR/SYK/SYT7/SNX4/RAB3D	9
GO:0070555	response to interleukin-1	21/2053	143/18722	0.100948918386879	0.242568486312085	CCL3L3/CCL3/CYBA/CCL4/LGALS9/PYCARD/GBP2/KLF2/IRAK3/IL1B/APP/GBP1/CEBPB/IL1RN/ICAM1/CXCL8/USP10/SIRPA/MYD88/RBMX/RPS6KA5	21
GO:0035966	response to topologically incorrect protein	23/2053	159/18722	0.101430926796244	0.24358040310888	HSPD1/HSP90AA1/HSP90AB1/SERP1/HSPE1/HSPA5/SERPINH1/CCND1/HSPA8/HSPA6/FBXO6/UBXN4/SDF2L1/MANF/HSPA14/HSPA1A/PPP1R15A/ATF3/VCP/HSPA9/TM7SF3/DNAJB14/DNAJB9	23
GO:0007254	JNK cascade	24/2053	167/18722	0.101451237894849	0.24358040310888	NCF1/PYCARD/HMGB1/EGFR/LRRK2/HACD3/TNF/TLR4/DUSP9/IL1B/GSTP1/APP/PTGER4/TLR7/GADD45B/PTK2B/HRAS/TRIB1/MARVELD3/SIRPA/SDCBP/MYD88/RASSF2/IGF1R	24
GO:0006874	cellular calcium ion homeostasis	58/2053	448/18722	0.101888663953886	0.244532793489327	PTPRC/CXCR4/CD52/CORO1A/CCL3/CYBA/FPR1/C5AR1/LYN/FPR3/SLC8A1/C3AR1/GPR65/HMGB1/JAK2/LPAR6/CCR1/HSP90B1/CD36/APP/CCR2/PTGER4/CXCL10/CD24/S1PR4/TGM2/PTPN6/CCRL2/CALR/CCDC47/ATP2B1/PTK2B/TRPV2/P2RX7/GNA15/CYSLTR1/PRKCB/GJA1/CX3CR1/CAMK2D/TRPM2/CALM2/MCOLN3/VDR/ITGAV/IMMT/STOML2/AFG3L2/FIS1/YWHAE/MCUR1/DMD/TCIRG1/BNIP3/FKBP1A/C1QTNF1/UBASH3B/HEXB	58
GO:0014032	neural crest cell development	13/2053	81/18722	0.102603554080765	0.245961259928227	FN1/NRP2/BMP7/LAMA5/SEMA4A/SEMA6A/NRP1/ISL1/FOLR1/SEMA6D/TCOF1/CORO1C/FOXC1	13
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	13/2053	81/18722	0.102603554080765	0.245961259928227	PEG10/SKIL/FBN2/FBN1/HSPA5/LDLRAD4/LTBP1/HSPA1A/FKBP1A/ZNF451/TGFBR3/EID2/PPARG	13
GO:0006402	mRNA catabolic process	32/2053	232/18722	0.102606838933392	0.245961259928227	VIM/SLC11A1/ZFP36/ZFP36L2/FUS/CARHSP1/PABPC1/ZFP36L1/NPM1/HNRNPR/SERBP1/BTG2/EXOSC8/LSM2/LSM4/LSM5/HNRNPD/UPF3A/MAGOHB/LSM7/MYD88/MAGOH/KHSRP/SND1/HNRNPA0/APEX1/HSPA1A/AGO2/E2F1/MRTO4/YBX1/MAPK14	32
GO:0032620	interleukin-17 production	8/2053	44/18722	0.103035628775697	0.246595042941438	TGFB1/NCKAP1L/TLR4/IL27RA/SPHK1/MYD88/PHB/IL18	8
GO:0032660	regulation of interleukin-17 production	8/2053	44/18722	0.103035628775697	0.246595042941438	TGFB1/NCKAP1L/TLR4/IL27RA/SPHK1/MYD88/PHB/IL18	8
GO:0046006	regulation of activated T cell proliferation	8/2053	44/18722	0.103035628775697	0.246595042941438	LGALS9/PYCARD/LILRB4/HMGB1/RPS3/CD24/IL27RA/IL18	8
GO:0060711	labyrinthine layer development	8/2053	44/18722	0.103035628775697	0.246595042941438	SPINT1/SPINT2/JUNB/SOCS3/VASH1/BMP7/ZFP36L1/GRB2	8
GO:0071300	cellular response to retinoic acid	11/2053	66/18722	0.103173428633115	0.246826384289748	LYN/KLF4/SERPINF1/PTK2B/PHB2/SLC6A4/HDAC2/TWF2/YAP1/YES1/NDUFA13	11
GO:0032984	protein-containing complex disassembly	31/2053	224/18722	0.103320183787696	0.246836531142277	PLEK/CAPG/STMN1/TNF/IRAK3/DSTN/SUPT16H/RPL23/VMP1/DDIT4/SET/HSPA8/RDX/CIB1/TPX2/HMGA1/CKAP2/SMARCC1/TWF2/SCIN/MID1IP1/SPTBN1/EPS8/ARHGEF2/IGF1R/BNIP3/LIMA1/INSR/VCP/TRIOBP/CFL1	31
GO:0000132	establishment of mitotic spindle orientation	6/2053	30/18722	0.103547924814185	0.246836531142277	ITGB1/MAD2L1/GJA1/NDC80/GPSM2/DYNLT1	6
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	6/2053	30/18722	0.103547924814185	0.246836531142277	TGFB1/APP/BMP7/SPHK1/CALM2/PRKAG2	6
GO:0017145	stem cell division	6/2053	30/18722	0.103547924814185	0.246836531142277	EVI2B/ZFP36L2/NOTCH1/GNL3/CDK2AP2/ING2	6
GO:0034390	smooth muscle cell apoptotic process	6/2053	30/18722	0.103547924814185	0.246836531142277	SOD2/ARRB2/DNMT1/CDKN2A/STK4/PPARG	6
GO:0034391	regulation of smooth muscle cell apoptotic process	6/2053	30/18722	0.103547924814185	0.246836531142277	SOD2/ARRB2/DNMT1/CDKN2A/STK4/PPARG	6
GO:0070168	negative regulation of biomineral tissue development	6/2053	30/18722	0.103547924814185	0.246836531142277	SRGN/CCL3/TGFB1/CCR1/NOTCH1/PTK2B	6
GO:0070229	negative regulation of lymphocyte apoptotic process	6/2053	30/18722	0.103547924814185	0.246836531142277	CD74/TSC22D3/BCL6/SLC39A10/EFNA1/AURKB	6
GO:2000637	positive regulation of gene silencing by miRNA	6/2053	30/18722	0.103547924814185	0.246836531142277	ZFP36/TGFB1/EGFR/STAT3/AGO2/EIF4G1	6
GO:0031112	positive regulation of microtubule polymerization or depolymerization	7/2053	37/18722	0.104187638493539	0.2475745865193	RPS3/MET/CLIP1/ARL2/HSPA1A/AKAP9/DRG1	7
GO:0034260	negative regulation of GTPase activity	7/2053	37/18722	0.104187638493539	0.2475745865193	LRRK2/ARRB2/GMIP/HRAS/AMOT/RDX/ARL2	7
GO:0043029	T cell homeostasis	7/2053	37/18722	0.104187638493539	0.2475745865193	CORO1A/TSC22D3/LGALS9/NCKAP1L/PMAIP1/RPS6/TCIRG1	7
GO:0043687	post-translational protein modification	7/2053	37/18722	0.104187638493539	0.2475745865193	FN3KRP/DSCC1/ESCO2/ICMT/LCMT1/P3H1/WIPI2	7
GO:0048846	axon extension involved in axon guidance	7/2053	37/18722	0.104187638493539	0.2475745865193	VEGFA/NRP2/ALCAM/SEMA4A/SEMA6A/NRP1/SEMA6D	7
GO:0090218	positive regulation of lipid kinase activity	7/2053	37/18722	0.104187638493539	0.2475745865193	TGFB1/LYN/FGR/PTK2B/FLT1/VAV3/PTK2	7
GO:1902284	neuron projection extension involved in neuron projection guidance	7/2053	37/18722	0.104187638493539	0.2475745865193	VEGFA/NRP2/ALCAM/SEMA4A/SEMA6A/NRP1/SEMA6D	7
GO:1905332	positive regulation of morphogenesis of an epithelium	7/2053	37/18722	0.104187638493539	0.2475745865193	VEGFA/MAGED1/ITGAX/GJA1/GATA3/LGR4/MDK	7
GO:0018105	peptidyl-serine phosphorylation	42/2053	315/18722	0.104984255831946	0.249368778698208	CD44/TGFB1/EGFR/LRRK2/VEGFA/TNF/APP/SGK1/ARRB2/PRKDC/HSP90AA1/CLSPN/SYK/HSP90AB1/CAMK1D/CAMK1/CDK1/VRK1/PRKCB/DDIT4/CAMK2D/RPS6KA1/MAPKAPK3/TXN/RASSF2/HCLS1/TTK/MASTL/PARK7/DMD/CDK2/AURKB/TLK1/TFRC/STK4/PLK2/AKAP9/RPS6KA5/PWP1/PKN1/EIF4G1/MAPK14	42
GO:0010634	positive regulation of epithelial cell migration	25/2053	176/18722	0.106421262860963	0.252579990881244	TMSB4X/TGFB1/HMGB1/VEGFA/HMOX1/GRN/MET/GLIPR2/NRP2/CTSH/CALR/PTK2B/STAT5A/RRAS/HBEGF/NRP1/CIB1/GATA3/PLPP3/RAB25/ANXA3/PFN1/BCAR1/RHOB/PLK2	25
GO:0033135	regulation of peptidyl-serine phosphorylation	21/2053	144/18722	0.106580325644725	0.252579990881244	CD44/TGFB1/EGFR/VEGFA/TNF/APP/ARRB2/HSP90AA1/HSP90AB1/CAMK1/DDIT4/TXN/RASSF2/HCLS1/PARK7/DMD/TFRC/STK4/AKAP9/PWP1/EIF4G1	21
GO:2000241	regulation of reproductive process	24/2053	168/18722	0.106653681973518	0.252579990881244	TIMP1/ARHGDIB/DUSP1/RETN/VEGFA/PHLDA2/SERPINF1/PTAFR/LHFPL2/PRDX4/BMP7/RAD51AP1/NOTCH1/CALR/ASPM/GJA1/C1QBP/CIB1/FBXO5/HDAC2/TTK/AGO2/STK4/DEFB1	24
GO:0008643	carbohydrate transport	22/2053	152/18722	0.106752834923567	0.252579990881244	SLC2A3/TNF/AQP9/IL1B/SLC2A1/C3/MEF2A/HK2/PRKCB/SLC2A6/SLC35B4/FABP5/RAP1A/ASPSCR1/RHOQ/EZR/YES1/INSR/PEA15/MAPK14/PRKAG2/GPC3	22
GO:0050871	positive regulation of B cell activation	22/2053	152/18722	0.106752834923567	0.252579990881244	PTPRC/CD74/TNFSF13B/TGFB1/NCKAP1L/MEF2C/TLR4/SASH3/BTK/STAT6/SYK/BCL6/GPR183/SLC39A10/MSH2/INPP5D/VAV3/BAD/CDKN1A/RIF1/TFRC/CD320	22
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	10/2053	59/18722	0.107065890310792	0.252579990881244	TGFB1/LYN/KLF4/FGR/SOCS3/PTK2B/PIK3R5/FLT1/VAV3/PTK2	10
GO:0051353	positive regulation of oxidoreductase activity	10/2053	59/18722	0.107065890310792	0.252579990881244	CYBA/TNF/IL1B/PTK2B/DHFR/GNAI2/VDR/PARK7/GCH1/COX17	10
GO:0006635	fatty acid beta-oxidation	12/2053	74/18722	0.107198765975854	0.252579990881244	SLC27A2/ECI1/ECHS1/ACADVL/ECHDC2/ETFB/HADH/ETFA/ACAT2/ECI2/SLC25A17/ECH1	12
GO:0009201	ribonucleoside triphosphate biosynthetic process	12/2053	74/18722	0.107198765975854	0.252579990881244	TMSB4X/TGFB1/PARP1/TREM2/ALDOA/STAT3/STOML2/NME4/IMPDH2/VCP/NME1/PRKAG2	12
GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	12/2053	74/18722	0.107198765975854	0.252579990881244	PARP1/CALR/BRCA1/PHB2/ISL1/RHOA/NCOR2/YAP1/PHB/PARK7/SKP2/PKN1	12
GO:0001780	neutrophil homeostasis	4/2053	17/18722	0.107641172780557	0.252579990881244	HMGB1/CCR2/SH2B3/JAM3	4
GO:0009084	glutamine family amino acid biosynthetic process	4/2053	17/18722	0.107641172780557	0.252579990881244	GLUL/OAT/ASS1/PYCR2	4
GO:0016264	gap junction assembly	4/2053	17/18722	0.107641172780557	0.252579990881244	IL1B/GJA1/CNTNAP2/GJA5	4
GO:0021924	cell proliferation in external granule layer	4/2053	17/18722	0.107641172780557	0.252579990881244	PSMG1/SLC6A4/ATF5/RERE	4
GO:0021930	cerebellar granule cell precursor proliferation	4/2053	17/18722	0.107641172780557	0.252579990881244	PSMG1/SLC6A4/ATF5/RERE	4
GO:0030903	notochord development	4/2053	17/18722	0.107641172780557	0.252579990881244	ID3/EFNA1/YAP1/COBL	4
GO:0031573	mitotic intra-S DNA damage checkpoint signaling	4/2053	17/18722	0.107641172780557	0.252579990881244	MSH2/FANCD2/TIPIN/MDC1	4
GO:0035855	megakaryocyte development	4/2053	17/18722	0.107641172780557	0.252579990881244	PTPN6/FLI1/SH2B3/WASF2	4
GO:0036035	osteoclast development	4/2053	17/18722	0.107641172780557	0.252579990881244	TYROBP/LILRB1/FBN1/NOTCH2	4
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	4/2053	17/18722	0.107641172780557	0.252579990881244	SOCS3/SH2B3/SUZ12/PARP14	4
GO:0042772	DNA damage response, signal transduction resulting in transcription	4/2053	17/18722	0.107641172780557	0.252579990881244	BRCA2/SP100/CDKN1A/FOXM1	4
GO:0048532	anatomical structure arrangement	4/2053	17/18722	0.107641172780557	0.252579990881244	NRP2/HSPA5/TFAP2A/NRP1	4
GO:0055064	chloride ion homeostasis	4/2053	17/18722	0.107641172780557	0.252579990881244	TBXAS1/KCNQ1/KCNE3/ATP6V1B1	4
GO:0055083	monovalent inorganic anion homeostasis	4/2053	17/18722	0.107641172780557	0.252579990881244	TBXAS1/KCNQ1/KCNE3/ATP6V1B1	4
GO:0060033	anatomical structure regression	4/2053	17/18722	0.107641172780557	0.252579990881244	SPI1/FLT1/LRP5/SMAD5	4
GO:0070206	protein trimerization	4/2053	17/18722	0.107641172780557	0.252579990881244	CD74/ALOX5AP/SLC1A5/SIGMAR1	4
GO:0070293	renal absorption	4/2053	17/18722	0.107641172780557	0.252579990881244	SGK1/CLDN4/KCNQ1/MAGED2	4
GO:0090136	epithelial cell-cell adhesion	4/2053	17/18722	0.107641172780557	0.252579990881244	DSP/ITGB5/VCL/SERPINB8	4
GO:1901550	regulation of endothelial cell development	4/2053	17/18722	0.107641172780557	0.252579990881244	VEGFA/TNF/IL1B/VCL	4
GO:1903140	regulation of establishment of endothelial barrier	4/2053	17/18722	0.107641172780557	0.252579990881244	VEGFA/TNF/IL1B/VCL	4
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	4/2053	17/18722	0.107641172780557	0.252579990881244	STAT1/CD24/GATA3/YAP1	4
GO:0006473	protein acetylation	28/2053	201/18722	0.110020725417872	0.255534965230006	SPI1/IL1B/CAMK1/MORF4L2/BRCA1/HINT2/SET/CHEK1/HAT1/SPHK1/ISL1/SOX4/HDAC2/BRD7/GATA3/DSCC1/BRCA2/ESCO2/POLE3/EID1/USP22/PARK7/ZNF451/PHF20/YEATS4/ACTL6A/RPS6KA5/MBD3	28
GO:0030514	negative regulation of BMP signaling pathway	9/2053	52/18722	0.110725644861927	0.255534965230006	SORL1/SKIL/FBN1/LRP2/NOTCH1/CRIM1/UBE2D1/CTDSPL2/PPARG	9
GO:0001660	fever generation	3/2053	11/18722	0.111157709875052	0.255534965230006	TNF/IL1B/PTGES	3
GO:0001731	formation of translation preinitiation complex	3/2053	11/18722	0.111157709875052	0.255534965230006	RPL13A/EIF5/DENR	3
GO:0002645	positive regulation of tolerance induction	3/2053	11/18722	0.111157709875052	0.255534965230006	LILRB2/LILRB4/IRAK3	3
GO:0003139	secondary heart field specification	3/2053	11/18722	0.111157709875052	0.255534965230006	MEF2C/LRP2/ISL1	3
GO:0006086	acetyl-CoA biosynthetic process from pyruvate	3/2053	11/18722	0.111157709875052	0.255534965230006	MPC2/PDK4/PDHA1	3
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	3/2053	11/18722	0.111157709875052	0.255534965230006	UQCRQ/CYC1/UQCR10	3
GO:0006183	GTP biosynthetic process	3/2053	11/18722	0.111157709875052	0.255534965230006	NME4/IMPDH2/NME1	3
GO:0006188	IMP biosynthetic process	3/2053	11/18722	0.111157709875052	0.255534965230006	PAICS/AMPD3/PPAT	3
GO:0009128	purine nucleoside monophosphate catabolic process	3/2053	11/18722	0.111157709875052	0.255534965230006	PNP/AMPD3/DNPH1	3
GO:0009235	cobalamin metabolic process	3/2053	11/18722	0.111157709875052	0.255534965230006	MMAB/MTR/CD320	3
GO:0010269	response to selenium ion	3/2053	11/18722	0.111157709875052	0.255534965230006	GPX1/SOD2/ALAD	3
GO:0010918	positive regulation of mitochondrial membrane potential	3/2053	11/18722	0.111157709875052	0.255534965230006	STOML2/BAD/VCP	3
GO:0032329	serine transport	3/2053	11/18722	0.111157709875052	0.255534965230006	SLC1A5/SFXN3/SFXN1	3
GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	3/2053	11/18722	0.111157709875052	0.255534965230006	PARP1/YAP1/SKP2	3
GO:0033197	response to vitamin E	3/2053	11/18722	0.111157709875052	0.255534965230006	SRSF2/CCND1/ALAD	3
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	3/2053	11/18722	0.111157709875052	0.255534965230006	ACADVL/ETFB/ETFA	3
GO:0033625	positive regulation of integrin activation	3/2053	11/18722	0.111157709875052	0.255534965230006	PLEK/FERMT1/FERMT2	3
GO:0033690	positive regulation of osteoblast proliferation	3/2053	11/18722	0.111157709875052	0.255534965230006	HPSE/ITGAV/LRP5	3
GO:0033860	regulation of NAD(P)H oxidase activity	3/2053	11/18722	0.111157709875052	0.255534965230006	CYBA/GNAI2/PARK7	3
GO:0034770	histone H4-K20 methylation	3/2053	11/18722	0.111157709875052	0.255534965230006	BRCA1/KMT5A/PWP1	3
GO:0035404	histone-serine phosphorylation	3/2053	11/18722	0.111157709875052	0.255534965230006	VRK1/AURKB/RPS6KA5	3
GO:0036490	regulation of translation in response to endoplasmic reticulum stress	3/2053	11/18722	0.111157709875052	0.255534965230006	EIF2AK4/PPP1R15A/EIF4G1	3
GO:0042416	dopamine biosynthetic process	3/2053	11/18722	0.111157709875052	0.255534965230006	NR4A2/PARK7/GCH1	3
GO:0042451	purine nucleoside biosynthetic process	3/2053	11/18722	0.111157709875052	0.255534965230006	MTAP/PNP/ADK	3
GO:0042455	ribonucleoside biosynthetic process	3/2053	11/18722	0.111157709875052	0.255534965230006	MTAP/PNP/ADK	3
GO:0042789	mRNA transcription by RNA polymerase II	3/2053	11/18722	0.111157709875052	0.255534965230006	FLNA/C5AR1/STAT3	3
GO:0046129	purine ribonucleoside biosynthetic process	3/2053	11/18722	0.111157709875052	0.255534965230006	MTAP/PNP/ADK	3
GO:0048680	positive regulation of axon regeneration	3/2053	11/18722	0.111157709875052	0.255534965230006	FLNA/GRN/PTN	3
GO:0051574	positive regulation of histone H3-K9 methylation	3/2053	11/18722	0.111157709875052	0.255534965230006	BRCA1/RIF1/LMNA	3
GO:0061314	Notch signaling involved in heart development	3/2053	11/18722	0.111157709875052	0.255534965230006	GALNT11/NOTCH1/NOTCH2	3
GO:0061635	regulation of protein complex stability	3/2053	11/18722	0.111157709875052	0.255534965230006	HSPA8/TAPBP/SCOC	3
GO:0070341	fat cell proliferation	3/2053	11/18722	0.111157709875052	0.255534965230006	TREM2/TFDP1/E2F1	3
GO:0070344	regulation of fat cell proliferation	3/2053	11/18722	0.111157709875052	0.255534965230006	TREM2/TFDP1/E2F1	3
GO:0070417	cellular response to cold	3/2053	11/18722	0.111157709875052	0.255534965230006	NFKBIA/EIF2AK4/SLC9A1	3
GO:0071679	commissural neuron axon guidance	3/2053	11/18722	0.111157709875052	0.255534965230006	VEGFA/DAG1/NRP1	3
GO:0097048	dendritic cell apoptotic process	3/2053	11/18722	0.111157709875052	0.255534965230006	LGALS9/LYN/LILRB1	3
GO:0097494	regulation of vesicle size	3/2053	11/18722	0.111157709875052	0.255534965230006	RIN3/PICALM/AP2M1	3
GO:0106049	regulation of cellular response to osmotic stress	3/2053	11/18722	0.111157709875052	0.255534965230006	ARHGEF2/BAD/EFHD1	3
GO:1900222	negative regulation of amyloid-beta clearance	3/2053	11/18722	0.111157709875052	0.255534965230006	TNF/LRPAP1/IFNGR1	3
GO:1900426	positive regulation of defense response to bacterium	3/2053	11/18722	0.111157709875052	0.255534965230006	CYBA/HAVCR2/GRN	3
GO:1903238	positive regulation of leukocyte tethering or rolling	3/2053	11/18722	0.111157709875052	0.255534965230006	ITGA4/PTAFR/CCR2	3
GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	3/2053	11/18722	0.111157709875052	0.255534965230006	LAPTM5/CASP1/HSPA1A	3
GO:1903961	positive regulation of anion transmembrane transport	3/2053	11/18722	0.111157709875052	0.255534965230006	TCAF1/PTAFR/ITGB1	3
GO:1904181	positive regulation of membrane depolarization	3/2053	11/18722	0.111157709875052	0.255534965230006	TSPO/PARP1/ANK3	3
GO:1904464	regulation of matrix metallopeptidase secretion	3/2053	11/18722	0.111157709875052	0.255534965230006	TLR2/TLR4/IDH2	3
GO:1905050	positive regulation of metallopeptidase activity	3/2053	11/18722	0.111157709875052	0.255534965230006	MBP/CLDN4/STAT3	3
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	3/2053	11/18722	0.111157709875052	0.255534965230006	CEBPB/HSPA5/ATF3	3
GO:1990773	matrix metallopeptidase secretion	3/2053	11/18722	0.111157709875052	0.255534965230006	TLR2/TLR4/IDH2	3
GO:2000392	regulation of lamellipodium morphogenesis	3/2053	11/18722	0.111157709875052	0.255534965230006	CD44/KANK1/CORO1C	3
GO:2000644	regulation of receptor catabolic process	3/2053	11/18722	0.111157709875052	0.255534965230006	LAPTM5/DTX3L/MYLIP	3
GO:2000668	regulation of dendritic cell apoptotic process	3/2053	11/18722	0.111157709875052	0.255534965230006	LGALS9/LYN/LILRB1	3
GO:0001838	embryonic epithelial tube formation	18/2053	121/18722	0.111205677311176	0.255547324345867	TGFB1/SPINT1/SPINT2/LRP2/VASP/RPS7/RARA/BMP7/LMO4/SOX4/GATA3/FOLR1/KIF20B/PFN1/LUZP1/STK4/IRX2/COBL	18
GO:0071466	cellular response to xenobiotic stimulus	25/2053	177/18722	0.111651198744125	0.256472891448985	CXCR4/APOBEC3A/MEF2C/S100A12/EGFR/PCNA/FBP1/MCM7/IL1B/GSTP1/KCNQ1/HSPA5/AIM2/PDE4A/SULT1A1/UMPS/NUDT15/RNF149/RAP1A/QDPR/TFRC/VKORC1/NME1/E2F1/PPAT	25
GO:1902117	positive regulation of organelle assembly	11/2053	67/18722	0.111870685543524	0.256878726850802	MSN/LCP1/TNF/CCDC88A/RHOA/SDCBP/RALB/ATMIN/CENPJ/GPSM2/CCP110	11
GO:0018394	peptidyl-lysine acetylation	24/2053	169/18722	0.112022177753293	0.257029853353636	SPI1/IL1B/MORF4L2/BRCA1/HINT2/SET/CHEK1/HAT1/ISL1/SOX4/HDAC2/BRD7/GATA3/BRCA2/POLE3/EID1/USP22/PARK7/ZNF451/PHF20/YEATS4/ACTL6A/RPS6KA5/MBD3	24
GO:0021543	pallium development	24/2053	169/18722	0.112022177753293	0.257029853353636	BCL2A1/FLNA/PHACTR1/SLC2A1/ADGRG1/LAMB1/RARA/BTG2/ASPM/EZH2/UQCRQ/CNTNAP2/RHOA/GNG12/CDK6/ANXA3/TACC2/BAD/BNIP3/TRA2B/GLI3/MDK/KDM6B/NME1	24
GO:0060048	cardiac muscle contraction	20/2053	137/18722	0.112218861191272	0.257382709154293	CXCR4/FLNA/SLC8A1/DSP/KCNQ1/TNNI2/DSG2/GJA1/CAMK2D/KCNE3/GJA5/DSC2/CALM2/RGS2/SLC9A1/DLG1/DMD/GAA/AKAP9/SMAD5	20
GO:0051961	negative regulation of nervous system development	21/2053	145/18722	0.112404733844467	0.257710509387391	TSPO/SORL1/B2M/TLR2/SPP1/TNF/IL1B/BMP7/SEMA4A/NOTCH1/TREM2/ARHGAP4/SEMA6A/ID1/IDH2/ASCL2/NRP1/SEMA6D/PRTG/PTN/DYNLT1	21
GO:0050803	regulation of synapse structure or activity	30/2053	218/18722	0.113359466554826	0.259800152532068	SRGN/LILRB2/MEF2C/IL10RA/TLR2/TUBA1A/ABI3/LRRK2/TUBB/TNF/APP/NRP2/DAG1/CAMK1/SEMA4A/TREM2/PPT1/TPBG/HSPA8/RHOA/ACTR2/DLG5/EFNA1/VCP/PTN/CFL1/EIF4G1/CLSTN1/HOMER1/MAPK14	30
GO:0003009	skeletal muscle contraction	8/2053	45/18722	0.11392578558295	0.260203545297945	RCSD1/C12orf57/TNNI2/NR4A1/DMD/GAA/CHRNB1/HOMER1	8
GO:0030835	negative regulation of actin filament depolymerization	8/2053	45/18722	0.11392578558295	0.260203545297945	CAPG/RDX/TWF2/SCIN/SPTBN1/EPS8/LIMA1/TRIOBP	8
GO:0030850	prostate gland development	8/2053	45/18722	0.11392578558295	0.260203545297945	CRIP1/PSAP/SERPINF1/RARA/BMP7/NOTCH1/SMARCC1/GLI3	8
GO:0035384	thioester biosynthetic process	8/2053	45/18722	0.11392578558295	0.260203545297945	MPC2/ACSS1/TECR/PDK4/PPT1/SLC25A1/ACSL4/PDHA1	8
GO:0045910	negative regulation of DNA recombination	8/2053	45/18722	0.11392578558295	0.260203545297945	BCL6/RMI2/MSH2/MSH6/BLM/MAGEF1/RIF1/POLQ	8
GO:0048538	thymus development	8/2053	45/18722	0.11392578558295	0.260203545297945	MAFB/PRDX2/PRKDC/SOD1/LMO4/GATA3/PBX1/ASXL1	8
GO:0071616	acyl-CoA biosynthetic process	8/2053	45/18722	0.11392578558295	0.260203545297945	MPC2/ACSS1/TECR/PDK4/PPT1/SLC25A1/ACSL4/PDHA1	8
GO:0098534	centriole assembly	8/2053	45/18722	0.11392578558295	0.260203545297945	NPM1/BRCA1/CEP152/CDK2/CENPJ/SASS6/PLK2/CCP110	8
GO:1901985	positive regulation of protein acetylation	8/2053	45/18722	0.11392578558295	0.260203545297945	IL1B/CAMK1/BRCA1/ISL1/SOX4/BRD7/GATA3/RPS6KA5	8
GO:0003015	heart process	34/2053	251/18722	0.114047828347335	0.260383169742774	CXCR4/FLNA/SLC8A1/GPX1/JAK2/CELF2/DSP/MEF2A/SOD1/ATP2B1/KCNQ1/TNNI2/DSG2/GJA1/HBEGF/CAMK2D/KCNE3/GNAI2/EPAS1/GJA5/ADRB1/ISL1/DSC2/CALM2/YAP1/YWHAE/RGS2/SLC9A1/GCH1/DLG1/DMD/GAA/AKAP9/SMAD5	34
GO:0044282	small molecule catabolic process	49/2053	376/18722	0.114366206202516	0.261010740667591	APOBEC3A/ALDH2/UPP1/SDS/GCSH/KYNU/SLC27A2/DPYD/GLUL/ECI1/QPRT/IL4I1/ECHS1/HK3/CDA/PNKD/ADH5/DDAH2/HK2/ACADVL/GLDC/SDSL/ECHDC2/SULT1A1/ETFB/APOBEC3G/NUDT8/APOBEC3C/CDO1/PNP/HADH/OAT/LRP5/FUT8/ETFA/ACAT2/IMPA2/ABHD2/NUDT5/PARK7/BAD/QDPR/ECI2/SHMT1/GK/SLC25A17/ECH1/PPAT/ENOSF1	49
GO:0043502	regulation of muscle adaptation	15/2053	98/18722	0.114663752917782	0.261590310839047	AIF1/TNFRSF1B/KLF4/PARP1/MEF2A/DAG1/NOTCH1/HAMP/CAMK2D/IL6ST/PARP2/RGS2/SLC9A1/CAMK2G/LMNA	15
GO:0017157	regulation of exocytosis	28/2053	202/18722	0.11500947143356	0.262014969309111	ITGB2/HLA-F/SPI1/LGALS9/NCKAP1L/CD84/LYN/CD300A/RAC2/FGR/LRRK2/ITGAM/PTAFR/HMOX1/STXBP2/CCR2/ADGRE2/PRAM1/SYK/NOTCH1/PRKCB/GNAI2/SYT7/SNX4/SDCBP/RAB3D/RAP1A/CHRNA5	28
GO:0003148	outflow tract septum morphogenesis	5/2053	24/18722	0.115155579011354	0.262014969309111	LRP2/NRP2/ENG/NRP1/ISL1	5
GO:0010288	response to lead ion	5/2053	24/18722	0.115155579011354	0.262014969309111	APP/CDK4/PLSCR1/QDPR/ALAD	5
GO:0018196	peptidyl-asparagine modification	5/2053	24/18722	0.115155579011354	0.262014969309111	RPN2/DDOST/TUSC3/FUT8/ALG8	5
GO:0030859	polarized epithelial cell differentiation	5/2053	24/18722	0.115155579011354	0.262014969309111	MSN/FAT1/RHOA/AHI1/DLG5	5
GO:0070129	regulation of mitochondrial translation	5/2053	24/18722	0.115155579011354	0.262014969309111	C1QBP/UQCC2/TSFM/MALSU1/LRPPRC	5
GO:0071294	cellular response to zinc ion	5/2053	24/18722	0.115155579011354	0.262014969309111	TSPO/PARP1/HVCN1/MT1X/MT2A	5
GO:1902369	negative regulation of RNA catabolic process	12/2053	75/18722	0.115578509993913	0.262877581487293	SLC11A1/ZFP36/FUS/PABPC1/SLIRP/HNRNPD/MYD88/HNRNPA0/LRPPRC/E2F1/YBX1/MAPK14	12
GO:0010613	positive regulation of cardiac muscle hypertrophy	7/2053	38/18722	0.116284281433299	0.263683177853285	PARP1/MEF2A/HAMP/CAMK2D/IL6ST/PARP2/SLC9A1	7
GO:0030279	negative regulation of ossification	7/2053	38/18722	0.116284281433299	0.263683177853285	SRGN/CCL3/MEF2C/CCR1/NOTCH1/PTK2B/MDK	7
GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway	7/2053	38/18722	0.116284281433299	0.263683177853285	CALR/BRCA1/PHB2/ISL1/RHOA/NCOR2/PHB	7
GO:0042491	inner ear auditory receptor cell differentiation	7/2053	38/18722	0.116284281433299	0.263683177853285	SOD1/NOTCH1/KCNQ1/MCOLN3/ESRP1/TRIOBP/MYO7A	7
GO:0042596	fear response	7/2053	38/18722	0.116284281433299	0.263683177853285	MEF2C/DPP4/GJA1/ADRB1/VDAC1/MDK/EIF4G1	7
GO:0072538	T-helper 17 type immune response	7/2053	38/18722	0.116284281433299	0.263683177853285	CLEC7A/IL27RA/NOTCH1/IL6R/STAT3/PHB/NFKBIZ	7
GO:1903580	positive regulation of ATP metabolic process	7/2053	38/18722	0.116284281433299	0.263683177853285	TMSB4X/APP/TREM2/P2RX7/STAT3/INSR/VCP	7
GO:1903725	regulation of phospholipid metabolic process	7/2053	38/18722	0.116284281433299	0.263683177853285	PHB2/CHP1/APOC1/STOML2/DNAJC19/IDH1/PDGFA	7
GO:0008217	regulation of blood pressure	26/2053	186/18722	0.11643507455717	0.263825697637092	CYBA/SOD2/PTAFR/HMOX1/NAMPT/SGK1/CTSZ/SOD1/MME/NR2F2/ATP2B1/KCNQ1/EMP2/KCNK6/ADH5/ENPEP/GJA1/GJA5/ADRB1/SCPEP1/RHOA/ANPEP/LRP5/GCH1/ID2/PPARG	26
GO:1902115	regulation of organelle assembly	26/2053	186/18722	0.11643507455717	0.263825697637092	MSN/LCP1/HCK/ABI3/LRRK2/TNF/NPM1/BRCA1/CCDC88A/RDX/RHOA/SDCBP/RALB/TPR/YAP1/EZR/VDAC3/HSPA1A/ATMIN/CENPJ/CHMP4C/PLK2/GPSM2/DRG1/CCP110/ODF2L	26
GO:0006081	cellular aldehyde metabolic process	10/2053	60/18722	0.116550914555688	0.263988481439836	AKR7A2/ALDH7A1/PNKD/ADH5/IDH2/ALDH1A1/GRHPR/IDH1/PARK7/GLO1	10
GO:0032148	activation of protein kinase B activity	6/2053	31/18722	0.117124258988421	0.264787322505849	PPIA/CCDC88A/TXN/PARK7/INSR/IL18	6
GO:0060045	positive regulation of cardiac muscle cell proliferation	6/2053	31/18722	0.117124258988421	0.264787322505849	MEF2C/CDK1/NOTCH1/YAP1/TGFBR3/MAPK14	6
GO:0060148	positive regulation of posttranscriptional gene silencing	6/2053	31/18722	0.117124258988421	0.264787322505849	ZFP36/TGFB1/EGFR/STAT3/AGO2/EIF4G1	6
GO:0060390	regulation of SMAD protein signal transduction	6/2053	31/18722	0.117124258988421	0.264787322505849	TGFB1/JAK2/PARP1/RBPMS/SPTBN1/PPARG	6
GO:0110150	negative regulation of biomineralization	6/2053	31/18722	0.117124258988421	0.264787322505849	SRGN/CCL3/TGFB1/CCR1/NOTCH1/PTK2B	6
GO:0043487	regulation of RNA stability	24/2053	170/18722	0.117556793910627	0.265665070984469	VIM/SLC11A1/TNFRSF1B/ZFP36/ZFP36L2/FUS/CARHSP1/PABPC1/LIN28B/ZFP36L1/NPM1/HNRNPR/SERBP1/BTG2/EXOSC8/HNRNPD/MYD88/KHSRP/HNRNPA0/APEX1/AGO2/E2F1/YBX1/MAPK14	24
GO:0051208	sequestering of calcium ion	18/2053	122/18722	0.117785754340924	0.266082276372568	PTPRC/CORO1A/CCL3/CYBA/LYN/SLC8A1/HSP90B1/CXCL10/PTPN6/CALR/PTK2B/CAMK2D/TRPM2/CALM2/MCOLN3/DMD/FKBP1A/UBASH3B	18
GO:0090257	regulation of muscle system process	34/2053	252/18722	0.118599481626381	0.267819679999354	AIF1/TNFRSF1B/SLC8A1/KLF4/PARP1/DSP/PTAFR/DOCK4/MEF2A/DAG1/SOD1/C12orf57/NOTCH1/ATP2B1/KCNQ1/TNNI2/NR4A1/HAMP/DSG2/CAMK2D/GJA5/SPHK1/DSC2/RHOA/CALM2/IL6ST/PARP2/RGS2/SLC9A1/CAMK2G/DLG1/DMD/AKAP9/LMNA	34
GO:0050807	regulation of synapse organization	29/2053	211/18722	0.119209836504457	0.269096696398323	SRGN/LILRB2/MEF2C/IL10RA/TLR2/TUBA1A/ABI3/LRRK2/TUBB/TNF/APP/NRP2/DAG1/CAMK1/SEMA4A/TREM2/TPBG/HSPA8/RHOA/ACTR2/DLG5/EFNA1/VCP/PTN/CFL1/EIF4G1/CLSTN1/HOMER1/MAPK14	29
GO:0010975	regulation of neuron projection development	57/2053	445/18722	0.119749806257146	0.270213929124813	VIM/LGALS1/FLNA/LYN/B2M/FN1/SKIL/ABI3/KLF4/SPP1/LRRK2/VEGFA/ITGA6/PLXNC1/SERPINF1/GRN/CTSZ/PREX1/CAMK1D/CAMK1/TENM3/BMP7/S100A9/SEMA4A/ARHGAP4/PTK2B/HSPA5/TRPV2/SEMA6A/ID1/EZH2/CCDC88A/KANK1/ITM2C/NRP1/RHOA/ACTR2/CIB1/HDAC2/GOLGA4/GATA3/TWF2/SEMA6D/EFNA1/RAP1A/PTPRF/OBSL1/RGS2/CAMK2G/MDK/NME1/P3H1/PTN/CFL1/COBL/MYLIP/DYNLT1	57
GO:0006354	DNA-templated transcription, elongation	14/2053	91/18722	0.120582902203361	0.271787157483157	CDCA4/SUPT16H/RTF1/EZH2/CHEK1/BRD4/POLR2I/TSFM/ZNF326/HMGN1/HTATSF1/ELL2/RNF8/NELFCD	14
GO:0014033	neural crest cell differentiation	14/2053	91/18722	0.120582902203361	0.271787157483157	MEF2C/FN1/NRP2/BMP7/LAMA5/SEMA4A/SEMA6A/NRP1/ISL1/FOLR1/SEMA6D/TCOF1/CORO1C/FOXC1	14
GO:0055006	cardiac cell development	14/2053	91/18722	0.120582902203361	0.271787157483157	SLC8A1/VEGFA/MEF2A/CDK1/NOTCH1/HAMP/ISL1/PARP2/OBSL1/RGS2/FHL2/TGFBR3/LMNA/TBX3	14
GO:0031640	killing of cells of other organism	11/2053	68/18722	0.120974744421044	0.27239907807242	LYZ/CLEC7A/S100A12/TREM1/SYK/HAMP/P2RX7/HMGN2/RPS19/MYD88/GAPDH	11
GO:0060411	cardiac septum morphogenesis	11/2053	68/18722	0.120974744421044	0.27239907807242	LRP2/NRP2/BMP7/ENG/NOTCH1/NRP1/ISL1/NOTCH2/SOX4/TGFBR3/TBX3	11
GO:0031279	regulation of cyclase activity	9/2053	53/18722	0.121126790049536	0.27239907807242	GNAS/CCR2/P2RY13/TIMP2/GNAI2/CAP1/CALM2/AKAP9/MAPK14	9
GO:0032784	regulation of DNA-templated transcription, elongation	9/2053	53/18722	0.121126790049536	0.27239907807242	SUPT16H/EZH2/BRD4/TSFM/ZNF326/HMGN1/HTATSF1/RNF8/NELFCD	9
GO:1903202	negative regulation of oxidative stress-induced cell death	9/2053	53/18722	0.121126790049536	0.27239907807242	PAGE4/GPX1/SOD2/LRRK2/MET/PPIA/TXN/PARK7/TRAP1	9
GO:1990090	cellular response to nerve growth factor stimulus	9/2053	53/18722	0.121126790049536	0.27239907807242	CORO1A/APP/ARPC3/HSPA5/ID1/CIB1/RAP1A/DYNC1LI2/E2F1	9
GO:0048469	cell maturation	24/2053	171/18722	0.123257350489414	0.277086587836823	CLEC7A/LRRK2/VEGFA/TYMS/KLF2/NR4A2/APP/C3/BTK/C1QA/PTK2B/CNTNAP2/AKR1B1/EPAS1/FAM210B/FBXO5/GATA3/BRCA2/ABHD2/CDKN1A/TFCP2L1/DEFB1/PPARG/RAC3	24
GO:0015849	organic acid transport	40/2053	303/18722	0.123788372264345	0.278172059299899	SLC11A1/SLC7A7/SLC16A3/LRP2/AQP9/IL1B/CD36/SLC2A1/SLC27A2/SLC38A1/SLC26A2/SYK/MPC2/ITGB1/LRRC8C/PLIN2/GJA1/SLC6A6/SLC25A1/FABP5/SLC1A5/SFXN3/ACSL4/SLC16A1/FOLR1/SLC19A1/SFXN1/FIS1/RGS2/SLC13A3/PTGES/SLC7A6/SLC38A9/SLC25A17/MPC1/SLC38A6/SLC3A2/PPARG/SLC1A3/SLC10A3	40
GO:0010976	positive regulation of neuron projection development	23/2053	163/18722	0.123832928398338	0.278172059299899	FLNA/LYN/ITGA6/SERPINF1/GRN/CAMK1D/CAMK1/TENM3/BMP7/S100A9/PTK2B/HSPA5/EZH2/ACTR2/TWF2/RAP1A/RGS2/MDK/NME1/P3H1/PTN/COBL/DYNLT1	23
GO:0043279	response to alkaloid	17/2053	115/18722	0.124121343583434	0.278715591878968	AIF1/CXCR4/SLC8A1/HSPD1/TGM2/HSP90AB1/PTK2B/RAD51/HSPA5/ICAM1/FOSB/CCNA2/BLM/HDAC2/PEA15/HOMER1/SLC1A3	17
GO:0006690	icosanoid metabolic process	18/2053	123/18722	0.124594702150308	0.279569264361199	CD74/TLR2/GPX1/ALOX5AP/MGST3/ALOX5/IL1B/GSTP1/SYK/TBXAS1/HPGD/AKR1B1/FABP5/LTA4H/ATP6V1B1/DPEP2/PTGES/MGLL	18
GO:0071482	cellular response to light stimulus	18/2053	123/18722	0.124594702150308	0.279569264361199	TIMP1/CRIP1/PCNA/PARP1/CARD16/MME/NPM1/PBK/CHEK1/DDB1/TRIAP1/POLD3/EIF2AK4/ERCC1/NMT1/CDKN1A/AURKB/PTN	18
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	19/2053	131/18722	0.124811220896246	0.279950402010271	SORL1/PEG10/SKIL/FBN2/FBN1/LRP2/NOTCH1/CRIM1/HSPA5/LDLRAD4/LTBP1/UBE2D1/HSPA1A/FKBP1A/ZNF451/TGFBR3/EID2/CTDSPL2/PPARG	19
GO:0001974	blood vessel remodeling	8/2053	46/18722	0.125409976609938	0.280663879022614	TGFB1/FLNA/MEF2C/CST3/CCR2/TGM2/EPAS1/FOXC1	8
GO:0035094	response to nicotine	8/2053	46/18722	0.125409976609938	0.280663879022614	B2M/TNF/HMOX1/KCNQ1/HDAC2/BAD/CHRNB1/CHRNA5	8
GO:0042398	cellular modified amino acid biosynthetic process	8/2053	46/18722	0.125409976609938	0.280663879022614	ALDH7A1/DHFR/GCLM/PLSCR1/PARK7/GCH1/PLOD2/CKMT1B	8
GO:0050919	negative chemotaxis	8/2053	46/18722	0.125409976609938	0.280663879022614	NRP2/DPP4/SEMA4A/SEMA6A/RHOA/ITGAV/SEMA6D/PDGFA	8
GO:0060976	coronary vasculature development	8/2053	46/18722	0.125409976609938	0.280663879022614	VEGFA/LRP2/NOTCH1/ADAMTS6/NRP1/CNTRL/TGFBR3/GPC3	8
GO:0070828	heterochromatin organization	8/2053	46/18722	0.125409976609938	0.280663879022614	HELLS/DNMT1/TPR/POLE3/TRIM28/MBD2/MBD3/SMARCA5	8
GO:0040014	regulation of multicellular organism growth	10/2053	61/18722	0.126488164703892	0.281441842071086	PLAC8/APP/SOD1/PPIB/STAT5A/ADRB1/STAT3/CDK4/AFG3L2/EZR	10
GO:0010660	regulation of muscle cell apoptotic process	13/2053	84/18722	0.126833652877085	0.281441842071086	SOD2/JAK2/HMOX1/ARRB2/DNMT1/BMP7/PTK2B/CAMK2D/CDKN2A/BNIP3/STK4/MDK/PPARG	13
GO:0002223	stimulatory C-type lectin receptor signaling pathway	4/2053	18/18722	0.126977177747738	0.281441842071086	TYROBP/CLEC7A/LYN/SYK	4
GO:0002295	T-helper cell lineage commitment	4/2053	18/18722	0.126977177747738	0.281441842071086	STAT6/IL6R/SPN/STAT3	4
GO:0006085	acetyl-CoA biosynthetic process	4/2053	18/18722	0.126977177747738	0.281441842071086	MPC2/ACSS1/PDK4/PDHA1	4
GO:0006337	nucleosome disassembly	4/2053	18/18722	0.126977177747738	0.281441842071086	SUPT16H/SET/HMGA1/SMARCC1	4
GO:0031643	positive regulation of myelination	4/2053	18/18722	0.126977177747738	0.281441842071086	TNFRSF1B/DAG1/ITGAX/PARD3	4
GO:0031649	heat generation	4/2053	18/18722	0.126977177747738	0.281441842071086	TNF/IL1B/ADRB1/PTGES	4
GO:0043217	myelin maintenance	4/2053	18/18722	0.126977177747738	0.281441842071086	CXCR4/SOD1/DEGS1/NDRG1	4
GO:0044247	cellular polysaccharide catabolic process	4/2053	18/18722	0.126977177747738	0.281441842071086	HMGB1/AOAH/AGL/GAA	4
GO:0045116	protein neddylation	4/2053	18/18722	0.126977177747738	0.281441842071086	RPL5/NAE1/EPAS1/NEDD8	4
GO:0046040	IMP metabolic process	4/2053	18/18722	0.126977177747738	0.281441842071086	PAICS/PNP/AMPD3/PPAT	4
GO:0050665	hydrogen peroxide biosynthetic process	4/2053	18/18722	0.126977177747738	0.281441842071086	CYBA/SOD2/SOD1/STAT3	4
GO:0060008	Sertoli cell differentiation	4/2053	18/18722	0.126977177747738	0.281441842071086	FLNA/RARA/ICAM1/CTSV	4
GO:0060749	mammary gland alveolus development	4/2053	18/18722	0.126977177747738	0.281441842071086	VEGFA/CCND1/PHB2/ID2	4
GO:0060973	cell migration involved in heart development	4/2053	18/18722	0.126977177747738	0.281441842071086	BMP7/ENG/NOTCH1/FOLR1	4
GO:0061377	mammary gland lobule development	4/2053	18/18722	0.126977177747738	0.281441842071086	VEGFA/CCND1/PHB2/ID2	4
GO:0061484	hematopoietic stem cell homeostasis	4/2053	18/18722	0.126977177747738	0.281441842071086	ADGRG1/FSTL1/SOX4/TCIRG1	4
GO:0071318	cellular response to ATP	4/2053	18/18722	0.126977177747738	0.281441842071086	HSP90B1/SOD1/P2RX7/P2RY11	4
GO:0071360	cellular response to exogenous dsRNA	4/2053	18/18722	0.126977177747738	0.281441842071086	IFIT1/COLEC12/RALB/DDX58	4
GO:0150079	negative regulation of neuroinflammatory response	4/2053	18/18722	0.126977177747738	0.281441842071086	PTPRC/TNFRSF1B/GRN/TREM2	4
GO:1900006	positive regulation of dendrite development	4/2053	18/18722	0.126977177747738	0.281441842071086	BMP7/EZH2/PTN/COBL	4
GO:1901673	regulation of mitotic spindle assembly	4/2053	18/18722	0.126977177747738	0.281441842071086	TPR/HSPA1A/CHMP4C/DRG1	4
GO:1902683	regulation of receptor localization to synapse	4/2053	18/18722	0.126977177747738	0.281441842071086	TYROBP/DAG1/HRAS/RAP1A	4
GO:1990840	response to lectin	4/2053	18/18722	0.126977177747738	0.281441842071086	TYROBP/CLEC7A/LYN/SYK	4
GO:1990858	cellular response to lectin	4/2053	18/18722	0.126977177747738	0.281441842071086	TYROBP/CLEC7A/LYN/SYK	4
GO:0071695	anatomical structure maturation	31/2053	229/18722	0.127132525771122	0.28168211027575	CLEC7A/LYL1/LRRK2/VEGFA/SNX10/TYMS/KLF2/NR4A2/APP/C3/BTK/DAG1/C1QA/PTK2B/CX3CR1/CNTNAP2/AKR1B1/FERMT1/EPAS1/RHOA/FAM210B/FBXO5/GATA3/BRCA2/ABHD2/CDKN1A/RERE/TFCP2L1/DEFB1/PPARG/RAC3	31
GO:0032465	regulation of cytokinesis	14/2053	92/18722	0.128679021397692	0.285003369651588	PLK3/PRC1/CDC6/RHOA/CALM2/KIF23/BRCA2/KIF20B/ECT2/AURKB/CHMP4C/PLK2/CCP110/E2F7	14
GO:0010463	mesenchymal cell proliferation	7/2053	39/18722	0.12907602490165	0.285145564655767	STAT1/BMP7/LRP5/PTN/LMNA/PDGFA/GPC3	7
GO:0014742	positive regulation of muscle hypertrophy	7/2053	39/18722	0.12907602490165	0.285145564655767	PARP1/MEF2A/HAMP/CAMK2D/IL6ST/PARP2/SLC9A1	7
GO:0032506	cytokinetic process	7/2053	39/18722	0.12907602490165	0.285145564655767	RHOA/ANLN/KIF20B/ECT2/AURKB/CHMP4C/RTKN	7
GO:0042417	dopamine metabolic process	7/2053	39/18722	0.12907602490165	0.285145564655767	ITGB2/ITGAM/NR4A2/COMT/PNKD/PARK7/GCH1	7
GO:0071548	response to dexamethasone	7/2053	39/18722	0.12907602490165	0.285145564655767	EGFR/PCNA/SERPINF1/PTAFR/ICAM1/DDIT4/ASS1	7
GO:0090224	regulation of spindle organization	7/2053	39/18722	0.12907602490165	0.285145564655767	TPX2/TPR/GNAI1/HSPA1A/CHMP4C/GPSM2/DRG1	7
GO:1903115	regulation of actin filament-based movement	7/2053	39/18722	0.12907602490165	0.285145564655767	DSP/DSG2/CAMK2D/GJA5/DSC2/DLG1/AKAP9	7
GO:0001678	cellular glucose homeostasis	24/2053	172/18722	0.129123416528287	0.285145564655767	HLA-DRB1/LGALS1/CYBA/UCP2/SERPINF1/MPC2/NUCKS1/TREM2/HK3/ICAM1/HK2/SLC29A1/HMGN3/KLF7/SOX4/GCLM/LRP5/FIS1/PHPT1/BAD/IGF1R/TRA2B/NME1/CCDC186	24
GO:0060840	artery development	15/2053	100/18722	0.12999120548968	0.286956303509228	VEGFA/LRP2/ENG/NOTCH1/HPGD/ADAMTS6/GJA5/NRP1/SOX4/FOLR1/CNTRL/LUZP1/GLI3/FOXC1/MDK	15
GO:0010611	regulation of cardiac muscle hypertrophy	11/2053	69/18722	0.13048004657773	0.287780769483217	TNFRSF1B/PARP1/MEF2A/NOTCH1/HAMP/CAMK2D/IL6ST/PARP2/RGS2/SLC9A1/LMNA	11
GO:0035148	tube formation	21/2053	148/18722	0.131033075403133	0.287780769483217	TGFB1/SPINT1/SPINT2/VEGFA/LRP2/VASP/RPS7/TGM2/RARA/BMP7/NOTCH1/LMO4/SOX4/GATA3/FOLR1/KIF20B/PFN1/LUZP1/STK4/IRX2/COBL	21
GO:0070507	regulation of microtubule cytoskeleton organization	21/2053	148/18722	0.131033075403133	0.287780769483217	STMN1/RPS3/MET/CLIP1/RHOA/CIB1/TPX2/CKAP2/ARL2/TPR/MID1IP1/SKA2/GNAI1/ARHGEF2/HSPA1A/CDK2AP2/SKA3/CHMP4C/AKAP9/GPSM2/DRG1	21
GO:0050768	negative regulation of neurogenesis	20/2053	140/18722	0.131412848358234	0.287780769483217	TSPO/SORL1/B2M/SPP1/TNF/IL1B/BMP7/SEMA4A/NOTCH1/TREM2/ARHGAP4/SEMA6A/ID1/IDH2/ASCL2/NRP1/SEMA6D/PRTG/PTN/DYNLT1	20
GO:0010644	cell communication by electrical coupling	6/2053	32/18722	0.131538641241243	0.287780769483217	SLC8A1/GJA1/CAMK2D/GJA5/CALM2/ANK3	6
GO:0010743	regulation of macrophage derived foam cell differentiation	6/2053	32/18722	0.131538641241243	0.287780769483217	MSR1/CD36/NFKBIA/ITGAV/IL18/PPARG	6
GO:0014044	Schwann cell development	6/2053	32/18722	0.131538641241243	0.287780769483217	DAG1/SOD1/ITGB4/PARD3/ADGRG6/NDRG1	6
GO:0045761	regulation of adenylate cyclase activity	6/2053	32/18722	0.131538641241243	0.287780769483217	CCR2/P2RY13/TIMP2/GNAI2/CAP1/AKAP9	6
GO:0090140	regulation of mitochondrial fission	6/2053	32/18722	0.131538641241243	0.287780769483217	LRRK2/STAT2/INF2/FIS1/BNIP3/PPARG	6
GO:0097345	mitochondrial outer membrane permeabilization	6/2053	32/18722	0.131538641241243	0.287780769483217	SLC25A5/BNIP3L/CHCHD10/HSPA1A/NMT1/BNIP3	6
GO:0035264	multicellular organism growth	19/2053	132/18722	0.131623104384878	0.287780769483217	PLAC8/KLF2/APP/SOD1/RARA/PPIB/ZFP36L1/STAT5A/ADRB1/NOTCH2/STAT3/ATF5/CDK4/AFG3L2/ARID5B/EZR/ERCC1/PLEKHA1/XRCC2	19
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	5/2053	25/18722	0.131659702038572	0.287780769483217	CYBA/EMP2/GJA1/GJA5/RHOA	5
GO:0003094	glomerular filtration	5/2053	25/18722	0.131659702038572	0.287780769483217	CYBA/EMP2/GJA1/GJA5/SULF2	5
GO:0006312	mitotic recombination	5/2053	25/18722	0.131659702038572	0.287780769483217	RAD51/RAD51C/BRCA2/RAD50/ERCC1	5
GO:0010447	response to acidic pH	5/2053	25/18722	0.131659702038572	0.287780769483217	CTSS/GPR65/SERPINF1/CHP1/SLC9A1	5
GO:0016540	protein autoprocessing	5/2053	25/18722	0.131659702038572	0.287780769483217	CTSL/CASP1/PARP1/AFG3L2/PISD	5
GO:0032469	endoplasmic reticulum calcium ion homeostasis	5/2053	25/18722	0.131659702038572	0.287780769483217	APP/TGM2/CCDC47/CAMK2D/FIS1	5
GO:0051204	protein insertion into mitochondrial membrane	5/2053	25/18722	0.131659702038572	0.287780769483217	HSP90AA1/TIMM13/PDCD5/NMT1/NDUFA13	5
GO:0072012	glomerulus vasculature development	5/2053	25/18722	0.131659702038572	0.287780769483217	PECAM1/BMP7/NOTCH1/IL6R/NOTCH2	5
GO:0086064	cell communication by electrical coupling involved in cardiac conduction	5/2053	25/18722	0.131659702038572	0.287780769483217	SLC8A1/GJA1/CAMK2D/GJA5/CALM2	5
GO:0090169	regulation of spindle assembly	5/2053	25/18722	0.131659702038572	0.287780769483217	TPR/HSPA1A/CHMP4C/GPSM2/DRG1	5
GO:0090312	positive regulation of protein deacetylation	5/2053	25/18722	0.131659702038572	0.287780769483217	LRRK2/VEGFA/BCL6/JDP2/ING2	5
GO:0090382	phagosome maturation	5/2053	25/18722	0.131659702038572	0.287780769483217	CORO1A/RAB32/SYT7/TCIRG1/MYO7A	5
GO:0140448	signaling receptor ligand precursor processing	5/2053	25/18722	0.131659702038572	0.287780769483217	CTSL/CASP1/CTSZ/MME/ENPEP	5
GO:1901623	regulation of lymphocyte chemotaxis	5/2053	25/18722	0.131659702038572	0.287780769483217	CCL3/CCL4/CCR2/CXCL10/PTK2B	5
GO:1902993	positive regulation of amyloid precursor protein catabolic process	5/2053	25/18722	0.131659702038572	0.287780769483217	LYN/TNF/EFNA1/IFNGR1/PICALM	5
GO:1903959	regulation of anion transmembrane transport	5/2053	25/18722	0.131659702038572	0.287780769483217	TCAF1/PTAFR/ITGB1/GOPC/RGS2	5
GO:0034765	regulation of ion transmembrane transport	62/2053	491/18722	0.131979763665621	0.288375302983877	CTSS/TMSB4X/CYBB/FXYD5/CORO1A/CYBA/FLNA/LYN/SLC8A1/MEF2C/TCAF1/APP/PTAFR/FXYD3/CCR2/CXCL10/HVCN1/GLRX/IFNGR2/PTPN6/ITGB1/KCNAB2/TREM2/CATSPER1/KCNQ1/PTK2B/HAMP/KCNK6/P2RX7/VMP1/TSPAN13/PHB2/CAMK2D/KCNMB1/KCNE3/CHP1/GJA5/CALM2/CLIC1/C4orf3/ANK3/CD63/KCNN4/VDAC1/GOPC/YWHAE/RGS2/SLC9A1/PARK7/COMMD1/DLG1/DMD/TCIRG1/FKBP1A/PTPN3/UBASH3B/AKAP9/CAPN1/HOMER1/TMEM109/ACTN4/COX17	62
GO:0086002	cardiac muscle cell action potential involved in contraction	9/2053	54/18722	0.132035794344752	0.288392706977979	FLNA/DSP/KCNQ1/DSG2/GJA1/KCNE3/GJA5/DSC2/DLG1	9
GO:0030433	ubiquitin-dependent ERAD pathway	13/2053	85/18722	0.13557079172044	0.294932877407819	HSP90B1/CALR/CCDC47/HSPA5/FBXO6/UBXN4/USP14/SVIP/SGTB/VCP/DNAJB14/DNAJB9/UBE4B	13
GO:0055072	iron ion homeostasis	13/2053	85/18722	0.13557079172044	0.294932877407819	SLC11A1/B2M/FTH1/FTL/HMOX1/SLC40A1/SLC25A37/SOD1/HAMP/EPAS1/EIF2AK1/TFRC/PICALM	13
GO:0097006	regulation of plasma lipoprotein particle levels	13/2053	85/18722	0.13557079172044	0.294932877407819	MSR1/CD36/HMOX1/LRPAP1/CSK/TREM2/PLA2G7/APOC1/LIPA/KHSRP/CNPY2/MYLIP/LDLRAP1	13
GO:0001821	histamine secretion	3/2053	12/18722	0.136652233198956	0.294932877407819	LYN/BTK/SNX4	3
GO:0002328	pro-B cell differentiation	3/2053	12/18722	0.136652233198956	0.294932877407819	PRKDC/NOTCH1/SOX4	3
GO:0002664	regulation of T cell tolerance induction	3/2053	12/18722	0.136652233198956	0.294932877407819	HLA-B/LILRB2/LILRB4	3
GO:0003207	cardiac chamber formation	3/2053	12/18722	0.136652233198956	0.294932877407819	MEF2C/NOTCH1/SOX4	3
GO:0006620	posttranslational protein targeting to endoplasmic reticulum membrane	3/2053	12/18722	0.136652233198956	0.294932877407819	HSPA5/SEC63/SGTB	3
GO:0007614	short-term memory	3/2053	12/18722	0.136652233198956	0.294932877407819	SERPINF1/COMT/MDK	3
GO:0016554	cytidine to uridine editing	3/2053	12/18722	0.136652233198956	0.294932877407819	APOBEC3A/APOBEC3G/APOBEC3C	3
GO:0021559	trigeminal nerve development	3/2053	12/18722	0.136652233198956	0.294932877407819	TFAP2A/NRP1/ISL1	3
GO:0031453	positive regulation of heterochromatin assembly	3/2053	12/18722	0.136652233198956	0.294932877407819	DNMT1/TPR/TRIM28	3
GO:0045916	negative regulation of complement activation	3/2053	12/18722	0.136652233198956	0.294932877407819	CD46/CD59/SERPING1	3
GO:0046185	aldehyde catabolic process	3/2053	12/18722	0.136652233198956	0.294932877407819	PNKD/ADH5/PARK7	3
GO:0048934	peripheral nervous system neuron differentiation	3/2053	12/18722	0.136652233198956	0.294932877407819	RUNX1/RUNX3/ISL1	3
GO:0048935	peripheral nervous system neuron development	3/2053	12/18722	0.136652233198956	0.294932877407819	RUNX1/RUNX3/ISL1	3
GO:0051340	regulation of ligase activity	3/2053	12/18722	0.136652233198956	0.294932877407819	TMSB4X/GCLM/MID1IP1	3
GO:0060019	radial glial cell differentiation	3/2053	12/18722	0.136652233198956	0.294932877407819	RHOA/STAT3/GLI3	3
GO:0061517	macrophage proliferation	3/2053	12/18722	0.136652233198956	0.294932877407819	CSF1R/TREM2/PTK2	3
GO:0070213	protein auto-ADP-ribosylation	3/2053	12/18722	0.136652233198956	0.294932877407819	PARP1/PARP2/PARP12	3
GO:0070572	positive regulation of neuron projection regeneration	3/2053	12/18722	0.136652233198956	0.294932877407819	FLNA/GRN/PTN	3
GO:0071287	cellular response to manganese ion	3/2053	12/18722	0.136652233198956	0.294932877407819	LRRK2/APP/HSPA5	3
GO:0072520	seminiferous tubule development	3/2053	12/18722	0.136652233198956	0.294932877407819	ADGRG1/UBB/ING2	3
GO:0072711	cellular response to hydroxyurea	3/2053	12/18722	0.136652233198956	0.294932877407819	RAD51/BLM/TIMELESS	3
GO:0090557	establishment of endothelial intestinal barrier	3/2053	12/18722	0.136652233198956	0.294932877407819	ICAM1/MYD88/TJP1	3
GO:0120263	positive regulation of heterochromatin organization	3/2053	12/18722	0.136652233198956	0.294932877407819	DNMT1/TPR/TRIM28	3
GO:0140289	protein mono-ADP-ribosylation	3/2053	12/18722	0.136652233198956	0.294932877407819	PARP9/PARP14/PARP12	3
GO:0150065	regulation of deacetylase activity	3/2053	12/18722	0.136652233198956	0.294932877407819	LRRK2/VEGFA/CAMK2D	3
GO:1901503	ether biosynthetic process	3/2053	12/18722	0.136652233198956	0.294932877407819	LPCAT2/ALOX5/CHPT1	3
GO:1905709	negative regulation of membrane permeability	3/2053	12/18722	0.136652233198956	0.294932877407819	HK2/BNIP3/DYNLT1	3
GO:1990034	calcium ion export across plasma membrane	3/2053	12/18722	0.136652233198956	0.294932877407819	ATP2B1/CALM2/YWHAE	3
GO:2000009	negative regulation of protein localization to cell surface	3/2053	12/18722	0.136652233198956	0.294932877407819	GOPC/COMMD1/PICALM	3
GO:2000727	positive regulation of cardiac muscle cell differentiation	3/2053	12/18722	0.136652233198956	0.294932877407819	TGFB1/MEF2C/ARRB2	3
GO:0060675	ureteric bud morphogenesis	10/2053	62/18722	0.136869101706129	0.295188573054197	VEGFA/MAGED1/LAMA5/TACSTD2/GATA3/PBX1/LGR4/DLG1/GLI3/GPC3	10
GO:1903078	positive regulation of protein localization to plasma membrane	10/2053	62/18722	0.136869101706129	0.295188573054197	EGFR/TNF/ITGB1/LGALS3/TREM2/CIB1/SPTBN1/RHOG/EZR/DLG1	10
GO:0009261	ribonucleotide catabolic process	8/2053	47/18722	0.137472221208261	0.295851265154076	UPP1/HINT1/DPYD/PDE4A/NUDT8/PNP/NUDT4/AMPD3	8
GO:0010761	fibroblast migration	8/2053	47/18722	0.137472221208261	0.295851265154076	TGFB1/SLC8A1/PDLIM1/ITGB1/ARHGAP4/ARID5B/CORO1C/PTK2	8
GO:0016574	histone ubiquitination	8/2053	47/18722	0.137472221208261	0.295851265154076	DDB1/DTX3L/USP22/PARK7/RNF8/UHRF1/HUWE1/UBE2N	8
GO:0031641	regulation of myelination	8/2053	47/18722	0.137472221208261	0.295851265154076	TYMP/TNFRSF1B/DAG1/ITGAX/RARA/PARD3/DLG1/PTN	8
GO:0045747	positive regulation of Notch signaling pathway	8/2053	47/18722	0.137472221208261	0.295851265154076	NOTCH1/BMP2K/MFNG/AAK1/STAT3/IL6ST/EPN2/YAP1	8
GO:0050885	neuromuscular process controlling balance	8/2053	47/18722	0.137472221208261	0.295851265154076	APP/TPP1/IGDCC3/GAA/HEXB/RAC3/SLC1A3/MYO7A	8
GO:0034976	response to endoplasmic reticulum stress	34/2053	256/18722	0.137938363975662	0.296748004250258	LRRK2/ALOX5/HSP90B1/P4HB/CEBPB/SERP1/PDIA3/CALR/CCDC47/PDIA4/HSPA5/CCND1/ERP29/CXCL8/PMAIP1/FBXO6/UBXN4/USP14/SVIP/SDF2L1/MANF/EIF2AK4/TMTC3/JUN/PARK7/HSPA1A/PPP1R15A/SGTB/ATF3/VCP/DNAJB14/EIF4G1/DNAJB9/UBE4B	34
GO:0021537	telencephalon development	33/2053	248/18722	0.139596720921106	0.300208001980873	CXCR4/BCL2A1/FLNA/PHACTR1/SLC8A1/LRRK2/SLC2A1/ADGRG1/LAMB1/RARA/C12orf57/BTG2/ASPM/EZH2/UQCRQ/CNTNAP2/ZSWIM6/RHOA/GNG12/ATF5/CDK6/ANXA3/NRGN/TACC2/BAD/BNIP3/TRA2B/GLI3/ID2/NUMB/MDK/KDM6B/NME1	33
GO:0016311	dephosphorylation	53/2053	417/18722	0.142016838815604	0.305303128947912	PTPRC/PLEK/TGFB1/NCKAP1L/LILRB2/MEF2C/CD300A/DUSP1/JAK2/LRRK2/FBP1/HSP90B1/TNF/PGP/HSP90AB1/PTPN6/PPIA/LGALS3/CD33/SLC39A10/CTDSPL/PPM1G/GNAI2/DAPP1/CHP1/CALM2/PTPN14/DUSP14/PLPP3/DUSP18/PTPRF/IMPA2/PNKP/ACP5/DUSP5/YWHAE/CAMK2G/INPP5D/MASTL/PHPT1/DLG1/PTP4A2/FKBP1A/PPP1R15A/ENSA/PTPN3/UBASH3B/CTDSPL2/PTPRU/PPP1R35/ILKAP/ENOPH1/URI1	53
GO:0060538	skeletal muscle organ development	23/2053	166/18722	0.142454495564766	0.305984975053782	TGFB1/MEF2C/VAMP5/FOS/GPX1/HIVEP3/GPCPD1/DAG1/NOTCH1/NR2F2/NR4A1/BTG2/UQCC2/RHOA/MYL6/ASS1/KLF5/GPC1/DMD/ATF3/BASP1/HOMER1/MAPK14	23
GO:0009069	serine family amino acid metabolic process	7/2053	40/18722	0.14253800087922	0.305984975053782	SDS/GCSH/DHFR/GLDC/CDO1/GCLM/SHMT1	7
GO:0031297	replication fork processing	7/2053	40/18722	0.14253800087922	0.305984975053782	SAMHD1/PCNA/NUCKS1/RAD51/BLM/BRCA2/MMS22L	7
GO:0043001	Golgi to plasma membrane protein transport	7/2053	40/18722	0.14253800087922	0.305984975053782	VAMP5/KRT18/CSK/GOLGA4/ANK3/SPTBN1/GOPC	7
GO:0000768	syncytium formation by plasma membrane fusion	9/2053	55/18722	0.143439835577596	0.307564593676659	TYROBP/CD53/CD9/PLEKHO1/CXCL10/CAMK1/ERVW-1/TREM2/MAPK14	9
GO:0042220	response to cocaine	9/2053	55/18722	0.143439835577596	0.307564593676659	HSPD1/TGM2/HSP90AB1/PTK2B/HSPA5/CCNA2/HDAC2/HOMER1/SLC1A3	9
GO:0140253	cell-cell fusion	9/2053	55/18722	0.143439835577596	0.307564593676659	TYROBP/CD53/CD9/PLEKHO1/CXCL10/CAMK1/ERVW-1/TREM2/MAPK14	9
GO:0043488	regulation of mRNA stability	22/2053	158/18722	0.143478882950162	0.307564593676659	VIM/SLC11A1/ZFP36/ZFP36L2/FUS/CARHSP1/PABPC1/ZFP36L1/NPM1/HNRNPR/SERBP1/BTG2/EXOSC8/HNRNPD/MYD88/KHSRP/HNRNPA0/APEX1/AGO2/E2F1/YBX1/MAPK14	22
GO:0022406	membrane docking	13/2053	86/18722	0.144630597584285	0.309922709109183	MSN/PLEK/STXBP2/STX11/ICAM1/VMP1/CHP1/RALB/RAB3IP/RAB3D/STX10/EZR/STX6	13
GO:0045926	negative regulation of growth	33/2053	249/18722	0.144838912071356	0.310147563321962	BST2/TGFB1/PLAC8/SPP1/FBP1/RBBP7/MT1X/SEMA4A/NOTCH1/BCL6/ARHGAP4/CDA/SEMA6A/PPT1/GJA1/BTG1/NRP1/SLC6A4/ADRB1/MT2A/NOTCH2/SEMA6D/SMARCA2/CDKN2A/PHB/RGS2/EI24/HSPA1A/CDKN1A/STK4/NDUFA13/DCBLD2/GPC3	33
GO:0046883	regulation of hormone secretion	33/2053	249/18722	0.144838912071356	0.310147563321962	HLA-DRB1/EGFR/UCP2/SPP1/JAK2/RETN/ALOX5/TNF/IL1B/GLUL/MPC2/SERP1/DPP4/GJA1/HMGN3/UQCC2/TRPM2/KLF7/ISL1/SYT7/SOX4/HADH/SNX4/ACSL4/SLC16A1/LRP5/PHPT1/BAD/TCIRG1/MIDN/C1QTNF1/ENSA/TM7SF3	33
GO:0006164	purine nucleotide biosynthetic process	26/2053	191/18722	0.144952772621634	0.310280640645667	TMSB4X/TGFB1/PARP1/SLC26A2/MPC2/ACSS1/TECR/TREM2/PDK4/PAICS/PPT1/ALDOA/SLC25A1/STAT3/ACSL4/GMPS/PDHA1/STOML2/NME4/ADK/IMPDH2/AMPD3/VCP/NME1/PPAT/PRKAG2	26
GO:0003012	muscle system process	57/2053	452/18722	0.145652551198891	0.310476403170288	AIF1/CXCR4/CYBA/TNFRSF1B/FLNA/SLC8A1/KLF4/PARP1/IL1B/DSP/PTAFR/HMOX1/DOCK4/RCSD1/MEF2A/CALD1/DAG1/SCO2/SOD1/C12orf57/NOTCH1/ATP2B1/KCNQ1/TNNI2/NR4A1/HAMP/DSG2/EZH2/GJA1/CAMK2D/KCNE3/ASPH/ALDOA/GJA5/SULF2/SPHK1/DSC2/RHOA/CALM2/TPM3/HDAC2/MYL6/IL6ST/PARP2/RGS2/SLC9A1/CAMK2G/DLG1/DMD/GAA/CHRNB1/PABPN1/AKAP9/LMNA/SMAD5/TBX3/HOMER1	57
GO:0014020	primary neural tube formation	14/2053	94/18722	0.145768051850545	0.310476403170288	TGFB1/SPINT1/SPINT2/LRP2/VASP/RPS7/RARA/BMP7/LMO4/FOLR1/KIF20B/PFN1/LUZP1/COBL	14
GO:0098727	maintenance of cell number	19/2053	134/18722	0.145882566635672	0.310476403170288	SPI1/ZFP36L2/KLF4/BMP7/SMC3/NOTCH1/RTF1/ASPM/EZH2/ASCL2/NOTCH2/STAT3/SOX4/LRP5/YAP1/GNL3/RIF1/PTN/TBX3	19
GO:0007409	axonogenesis	53/2053	418/18722	0.146076513541264	0.310476403170288	S100A6/FN1/RAC2/SKIL/ACTB/SPP1/STMN1/VEGFA/PLXNC1/NR4A2/APP/ITGA4/VASP/NRP2/HSP90AA1/HSP90AB1/DAG1/BSG/C12orf57/BMP7/LAMA5/ITGB1/ALCAM/SEMA4A/NOTCH1/ARHGAP4/TRPV2/SEMA6A/NRP1/KLF7/ISL1/NOTCH2/PARD3/GOLGA4/GATA3/EPHB4/TWF2/ANK3/SEMA6D/EFNA1/AFG3L2/SIAH1/RHOG/VCL/PARD6B/TOP2B/PALLD/GLI3/NUMB/PICALM/PTK2/RPS6KA5/COBL	53
GO:0060047	heart contraction	32/2053	241/18722	0.146631167282862	0.310476403170288	CXCR4/FLNA/SLC8A1/GPX1/JAK2/CELF2/DSP/MEF2A/SOD1/ATP2B1/KCNQ1/TNNI2/DSG2/GJA1/HBEGF/CAMK2D/KCNE3/EPAS1/GJA5/ADRB1/ISL1/DSC2/CALM2/YWHAE/RGS2/SLC9A1/GCH1/DLG1/DMD/GAA/AKAP9/SMAD5	32
GO:1903313	positive regulation of mRNA metabolic process	17/2053	118/18722	0.146667319053263	0.310476403170288	ZFP36/ZFP36L2/PABPC1/ZFP36L1/HNRNPR/BTG2/EXOSC8/HSPA8/HNRNPD/PRDX6/KHSRP/NCL/RBMX/AGO2/TRA2B/SNRNP70/PRPF19	17
GO:1905954	positive regulation of lipid localization	16/2053	110/18722	0.146702516437884	0.310476403170288	MSR1/SPP1/RETN/IL1B/CD36/C3/NFKBIA/TREM2/DBI/HILPDA/PLIN2/TRIAP1/PTGES/C1QTNF1/LDLRAP1/PPARG	16
GO:0003382	epithelial cell morphogenesis	6/2053	33/18722	0.14675128028902	0.310476403170288	SPINT2/MET/FAT1/RAB25/PALLD/RILPL2	6
GO:0048048	embryonic eye morphogenesis	6/2053	33/18722	0.14675128028902	0.310476403170288	EFEMP1/FBN2/FBN1/BMP7/MFAP5/TFAP2A	6
GO:0070570	regulation of neuron projection regeneration	6/2053	33/18722	0.14675128028902	0.310476403170288	FLNA/KLF4/SPP1/GRN/PTPRF/PTN	6
GO:0120033	negative regulation of plasma membrane bounded cell projection assembly	6/2053	33/18722	0.14675128028902	0.310476403170288	ABI3/KANK1/TACSTD2/YAP1/CCP110/ODF2L	6
GO:1900181	negative regulation of protein localization to nucleus	6/2053	33/18722	0.14675128028902	0.310476403170288	LILRB4/CD36/MAGED1/FERMT1/CHP1/TRIM29	6
GO:1901099	negative regulation of signal transduction in absence of ligand	6/2053	33/18722	0.14675128028902	0.310476403170288	PRDX2/TNF/IL1B/IFI6/MCL1/HSPA1A	6
GO:1902275	regulation of chromatin organization	6/2053	33/18722	0.14675128028902	0.310476403170288	MKI67/DNMT1/SSRP1/TPR/TLK1/TRIM28	6
GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	6/2053	33/18722	0.14675128028902	0.310476403170288	PRDX2/TNF/IL1B/IFI6/MCL1/HSPA1A	6
GO:0051146	striated muscle cell differentiation	37/2053	283/18722	0.147616854073174	0.310476403170288	CD53/TGFB1/CD9/SLC8A1/MEF2C/GPX1/PLEKHO1/VEGFA/CSRP2/ARRB2/CXCL10/MEF2A/RARA/CDK1/ITGB1/ERVW-1/NOTCH1/CALR/HAMP/MORF4L2/EZH2/KRT8/ISL1/CACYBP/PARP2/KLF5/OBSL1/RGS2/SLC9A1/FHL2/KDM6B/BHLHE41/LMNA/TBX3/YBX1/HOMER1/MAPK14	37
GO:0001696	gastric acid secretion	4/2053	19/18722	0.147638501276079	0.310476403170288	SNX10/SGK1/KCNQ1/HRH2	4
GO:0006007	glucose catabolic process	4/2053	19/18722	0.147638501276079	0.310476403170288	HK3/HK2/LRP5/BAD	4
GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	4/2053	19/18722	0.147638501276079	0.310476403170288	RGS10/GNA15/GNAI2/GNA11	4
GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	4/2053	19/18722	0.147638501276079	0.310476403170288	TYMS/DTYMK/NME4/NME1	4
GO:0010885	regulation of cholesterol storage	4/2053	19/18722	0.147638501276079	0.310476403170288	MSR1/CD36/TREM2/PPARG	4
GO:0015802	basic amino acid transport	4/2053	19/18722	0.147638501276079	0.310476403170288	SLC11A1/SLC7A7/SLC7A6/SLC38A9	4
GO:0030011	maintenance of cell polarity	4/2053	19/18722	0.147638501276079	0.310476403170288	NCKAP1L/PDLIM1/DLG5/SLC9A1	4
GO:0031290	retinal ganglion cell axon guidance	4/2053	19/18722	0.147638501276079	0.310476403170288	VEGFA/ALCAM/NRP1/ISL1	4
GO:0032026	response to magnesium ion	4/2053	19/18722	0.147638501276079	0.310476403170288	CD14/FBP1/CCND1/ANK3	4
GO:0035313	wound healing, spreading of epidermal cells	4/2053	19/18722	0.147638501276079	0.310476403170288	ITGA5/HBEGF/FERMT1/FERMT2	4
GO:0035461	vitamin transmembrane transport	4/2053	19/18722	0.147638501276079	0.310476403170288	LRP2/FOLR1/SLC19A1/SLC19A3	4
GO:0035728	response to hepatocyte growth factor	4/2053	19/18722	0.147638501276079	0.310476403170288	NRP1/GCLM/BCAR1/GAB1	4
GO:0044003	modulation by symbiont of host process	4/2053	19/18722	0.147638501276079	0.310476403170288	CD4/DAG1/PHB2/INSR	4
GO:0045019	negative regulation of nitric oxide biosynthetic process	4/2053	19/18722	0.147638501276079	0.310476403170288	TSPO/SIRPA/KHSRP/ACP5	4
GO:0046653	tetrahydrofolate metabolic process	4/2053	19/18722	0.147638501276079	0.310476403170288	TYMS/DHFR/GCH1/SHMT1	4
GO:0046716	muscle cell cellular homeostasis	4/2053	19/18722	0.147638501276079	0.310476403170288	SOD1/ALDOA/DMD/GAA	4
GO:0046794	transport of virus	4/2053	19/18722	0.147638501276079	0.310476403170288	BST2/CTSL/SIGLEC1/DYNLT1	4
GO:0051571	positive regulation of histone H3-K4 methylation	4/2053	19/18722	0.147638501276079	0.310476403170288	DNMT1/RTF1/BRCA1/KMT2E	4
GO:0060216	definitive hemopoiesis	4/2053	19/18722	0.147638501276079	0.310476403170288	ZFP36L2/LYL1/MFAP5/TGFBR3	4
GO:0086014	atrial cardiac muscle cell action potential	4/2053	19/18722	0.147638501276079	0.310476403170288	FLNA/KCNQ1/GJA1/GJA5	4
GO:0086026	atrial cardiac muscle cell to AV node cell signaling	4/2053	19/18722	0.147638501276079	0.310476403170288	FLNA/KCNQ1/GJA1/GJA5	4
GO:0086066	atrial cardiac muscle cell to AV node cell communication	4/2053	19/18722	0.147638501276079	0.310476403170288	FLNA/KCNQ1/GJA1/GJA5	4
GO:0097501	stress response to metal ion	4/2053	19/18722	0.147638501276079	0.310476403170288	MT1X/HSPA5/MT2A/PARK7	4
GO:0140131	positive regulation of lymphocyte chemotaxis	4/2053	19/18722	0.147638501276079	0.310476403170288	CCL3/CCL4/CCR2/PTK2B	4
GO:1900221	regulation of amyloid-beta clearance	4/2053	19/18722	0.147638501276079	0.310476403170288	TNF/LRPAP1/TREM2/IFNGR1	4
GO:1901659	glycosyl compound biosynthetic process	4/2053	19/18722	0.147638501276079	0.310476403170288	DTYMK/MTAP/PNP/ADK	4
GO:1901739	regulation of myoblast fusion	4/2053	19/18722	0.147638501276079	0.310476403170288	CD53/PLEKHO1/CXCL10/MAPK14	4
GO:1904406	negative regulation of nitric oxide metabolic process	4/2053	19/18722	0.147638501276079	0.310476403170288	TSPO/SIRPA/KHSRP/ACP5	4
GO:2000042	negative regulation of double-strand break repair via homologous recombination	4/2053	19/18722	0.147638501276079	0.310476403170288	RMI2/MAGEF1/RIF1/POLQ	4
GO:2000251	positive regulation of actin cytoskeleton reorganization	4/2053	19/18722	0.147638501276079	0.310476403170288	HCK/HRAS/NRP1/HCLS1	4
GO:2000269	regulation of fibroblast apoptotic process	4/2053	19/18722	0.147638501276079	0.310476403170288	BTG1/STK17A/STK17B/XRCC2	4
GO:2000738	positive regulation of stem cell differentiation	4/2053	19/18722	0.147638501276079	0.310476403170288	TACSTD2/FOXC1/PTN/PWP1	4
GO:0072171	mesonephric tubule morphogenesis	10/2053	63/18722	0.147683275774667	0.310476403170288	VEGFA/MAGED1/LAMA5/TACSTD2/GATA3/PBX1/LGR4/DLG1/GLI3/GPC3	10
GO:1902373	negative regulation of mRNA catabolic process	10/2053	63/18722	0.147683275774667	0.310476403170288	SLC11A1/ZFP36/FUS/PABPC1/HNRNPD/MYD88/HNRNPA0/E2F1/YBX1/MAPK14	10
GO:2000242	negative regulation of reproductive process	10/2053	63/18722	0.147683275774667	0.310476403170288	TIMP1/ARHGDIB/DUSP1/SERPINF1/PRDX4/BMP7/CALR/GJA1/FBXO5/TTK	10
GO:0002026	regulation of the force of heart contraction	5/2053	26/18722	0.149155324221412	0.312585380834254	SLC8A1/CAMK2D/ADRB1/SLC9A1/GAA	5
GO:0008535	respiratory chain complex IV assembly	5/2053	26/18722	0.149155324221412	0.312585380834254	SCO2/COX20/COA4/SCO1/COX17	5
GO:0016226	iron-sulfur cluster assembly	5/2053	26/18722	0.149155324221412	0.312585380834254	GLRX5/CIAO1/NUBP2/ISCA1/HSPA9	5
GO:0031163	metallo-sulfur cluster assembly	5/2053	26/18722	0.149155324221412	0.312585380834254	GLRX5/CIAO1/NUBP2/ISCA1/HSPA9	5
GO:0046639	negative regulation of alpha-beta T cell differentiation	5/2053	26/18722	0.149155324221412	0.312585380834254	HMGB1/RUNX1/BCL6/RUNX3/GLI3	5
GO:0051350	negative regulation of lyase activity	5/2053	26/18722	0.149155324221412	0.312585380834254	CCR2/P2RY13/GNAI2/PHPT1/AKAP9	5
GO:0060352	cell adhesion molecule production	5/2053	26/18722	0.149155324221412	0.312585380834254	COLEC12/IL1B/PPIA/NOTCH1/CXCL8	5
GO:0097205	renal filtration	5/2053	26/18722	0.149155324221412	0.312585380834254	CYBA/EMP2/GJA1/GJA5/SULF2	5
GO:2000108	positive regulation of leukocyte apoptotic process	5/2053	26/18722	0.149155324221412	0.312585380834254	LGALS9/LYN/MEF2C/ADAM8/CDKN2A	5
GO:0062012	regulation of small molecule metabolic process	43/2053	334/18722	0.149825997844751	0.313881280401015	TMSB4X/CD74/PLEK/SLC7A7/HMGB1/FBP1/PHLDA2/TNF/PARP1/IL1B/APP/PGP/PTAFR/SOD1/TREM2/CDA/PTK2B/PDK4/COMT/P2RX7/BRCA1/ACADVL/DDIT4/SLC2A6/SLC35B4/PMAIP1/DDB1/APOC1/FABP5/STAT3/ARL2/MID1IP1/NCOR2/PARK7/BAD/MIDN/C1QTNF1/LCMT1/INSR/VCP/PRKAG2/LDLRAP1/PPARG	43
GO:0035036	sperm-egg recognition	8/2053	48/18722	0.150093333658722	0.314002790081009	CD9/SPESP1/ALDOA/TCP1/FOLR1/CCT2/CCT4/CCT8	8
GO:0090311	regulation of protein deacetylation	8/2053	48/18722	0.150093333658722	0.314002790081009	LRRK2/VEGFA/BCL6/CAMK2D/JDP2/BEX4/ING2/NCAPG2	8
GO:0097720	calcineurin-mediated signaling	8/2053	48/18722	0.150093333658722	0.314002790081009	CLEC7A/TNF/HOMER3/CHP1/CIB1/SLC9A1/FHL2/NFAT5	8
GO:1903053	regulation of extracellular matrix organization	8/2053	48/18722	0.150093333658722	0.314002790081009	TNFRSF1B/TGFB1/CST3/RUNX1/DAG1/DPP4/NOTCH1/RGCC	8
GO:0043550	regulation of lipid kinase activity	11/2053	71/18722	0.150664398941693	0.314977837508766	TGFB1/LYN/KLF4/FGR/SOCS3/PTK2B/PIK3R5/FLT1/RBL1/VAV3/PTK2	11
GO:0050795	regulation of behavior	11/2053	71/18722	0.150664398941693	0.314977837508766	CCL3/MEF2C/RETN/GJA1/ADRB1/STAT3/HDAC2/AHI1/CFAP20/EIF2AK4/MDK	11
GO:0071333	cellular response to glucose stimulus	21/2053	151/18722	0.151373660751934	0.31635038819631	HLA-DRB1/LGALS1/CYBA/UCP2/SERPINF1/MPC2/TREM2/ICAM1/SLC29A1/HMGN3/KLF7/SOX4/GCLM/LRP5/FIS1/PHPT1/BAD/IGF1R/TRA2B/NME1/CCDC186	21
GO:0032412	regulation of ion transmembrane transporter activity	35/2053	267/18722	0.151599246579467	0.316711517923678	CTSS/TMSB4X/FXYD5/MEF2C/TCAF1/APP/PTAFR/FXYD3/CCR2/GLRX/IFNGR2/ITGB1/TREM2/KCNQ1/PTK2B/VMP1/PHB2/CAMK2D/KCNE3/CHP1/CALM2/C4orf3/ANK3/GOPC/YWHAE/SLC9A1/DLG1/DMD/FKBP1A/PTPN3/AKAP9/CAPN1/HOMER1/ACTN4/COX17	35
GO:0006520	cellular amino acid metabolic process	37/2053	284/18722	0.15269313233	0.318785537438527	SLC7A7/SDS/GCSH/KYNU/DPYD/GLUL/IL4I1/ECHS1/DHFR/COMT/DDAH2/GLDC/SDSL/ADI1/ALDH1A1/CDO1/IARS2/SMS/MTAP/OAT/GCLM/GMPS/ASS1/PARK7/PYCR2/NIT2/QDPR/PLOD2/SHMT1/RIMKLB/ASNSD1/GFPT1/MTR/PPAT/ENOSF1/SLC1A3/ENOPH1	37
GO:0051279	regulation of release of sequestered calcium ion into cytosol	12/2053	79/18722	0.152698272433054	0.318785537438527	CORO1A/CYBA/LYN/SLC8A1/CXCL10/PTPN6/PTK2B/CAMK2D/CALM2/DMD/FKBP1A/UBASH3B	12
GO:0061982	meiosis I cell cycle process	19/2053	135/18722	0.153325709816534	0.319984090051897	TOP2A/RAD51AP1/RAD51/CCNE1/UBB/RAD51C/MSH6/CKS2/FBXO5/RAD21/CCNE2/MND1/BRCA2/FANCD2/RAD50/PSMC3IP/ERCC1/TOP2B/ING2	19
GO:1901606	alpha-amino acid catabolic process	13/2053	87/18722	0.154007002361735	0.321294163480672	SDS/GCSH/KYNU/GLUL/IL4I1/DDAH2/GLDC/SDSL/CDO1/OAT/QDPR/SHMT1/PPAT	13
GO:0008593	regulation of Notch signaling pathway	14/2053	95/18722	0.154751518407352	0.322548264110377	CD46/NFKBIA/BMP7/GALNT11/NOTCH1/BCL6/LFNG/BMP2K/MFNG/AAK1/STAT3/IL6ST/EPN2/YAP1	14
GO:0042982	amyloid precursor protein metabolic process	14/2053	95/18722	0.154751518407352	0.322548264110377	LYN/SORL1/TNF/NSG1/DHCR24/PAWR/ITM2C/EFNA1/DLG1/FKBP1A/AGO2/IFNGR1/PICALM/LDLRAP1	14
GO:0006887	exocytosis	45/2053	352/18722	0.154769408728963	0.322548264110377	ITGB2/CORO1A/CCL3/PLEK/HLA-F/SPI1/LGALS9/NCKAP1L/CD84/LYN/LAT2/CD300A/TNFAIP2/HCK/RAC2/MYO1G/FGR/LRRK2/ITGAM/CCR1/PTAFR/HMOX1/STXBP2/CCR2/ADGRE2/PRAM1/BTK/STX11/SYK/NOTCH1/PRKCB/GNAI2/SYT7/SNX4/SDCBP/RALB/RAB3IP/RAB3D/SCIN/RAP1A/RAB25/ANXA3/PRSS12/CHRNA5/S100A13	45
GO:0002027	regulation of heart rate	15/2053	103/18722	0.155051157646225	0.323023245096302	SLC8A1/DSP/KCNQ1/DSG2/CAMK2D/KCNE3/EPAS1/ADRB1/ISL1/DSC2/CALM2/YWHAE/GCH1/DMD/AKAP9	15
GO:0001658	branching involved in ureteric bud morphogenesis	9/2053	56/18722	0.155323721873411	0.32347876821953	VEGFA/MAGED1/LAMA5/TACSTD2/PBX1/LGR4/DLG1/GLI3/GPC3	9
GO:0032409	regulation of transporter activity	40/2053	310/18722	0.156327906970552	0.325457127627797	CTSS/TMSB4X/FXYD5/MEF2C/ACTB/TCAF1/APP/PTAFR/FXYD3/SGK1/CCR2/GLRX/IFNGR2/ITGB1/TREM2/KCNQ1/PTK2B/VMP1/PHB2/GJA1/CAMK2D/KCNE3/CHP1/CALM2/C4orf3/ANK3/GOPC/YWHAE/SLC9A1/PARK7/DLG1/DMD/FKBP1A/PTPN3/AKAP9/CAPN1/HOMER1/ACTN4/PPARG/COX17	40
GO:0031062	positive regulation of histone methylation	7/2053	41/18722	0.156641128291127	0.325543363719807	DNMT1/RTF1/BRCA1/BRD4/KMT2E/RIF1/LMNA	7
GO:0050892	intestinal absorption	7/2053	41/18722	0.156641128291127	0.325543363719807	CD36/KCNQ1/HAMP/VDR/EZR/LIMA1/EPB41	7
GO:0051693	actin filament capping	7/2053	41/18722	0.156641128291127	0.325543363719807	CAPG/RDX/TWF2/SCIN/SPTBN1/EPS8/TRIOBP	7
GO:1905314	semi-lunar valve development	7/2053	41/18722	0.156641128291127	0.325543363719807	TNFRSF1B/TGFB1/NOTCH1/GJA5/NOTCH2/GATA3/EFNA1	7
GO:2000008	regulation of protein localization to cell surface	7/2053	41/18722	0.156641128291127	0.325543363719807	TYROBP/TNF/HSP90AB1/KCNAB2/GOPC/COMMD1/PICALM	7
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	52/2053	412/18722	0.1566948724038	0.325543363719807	LRRK2/HSP90B1/ARRB2/PLK3/HSP90AB1/PSMD7/CALR/CCDC47/HSPA5/ANAPC11/IFI27/PSMC3/UBE2C/PBK/KLHL42/TRIB1/DDB1/PSMD1/SIAH2/UBE2S/PSMB5/PSMC1/FBXO6/SMARCC1/PSMD14/SDCBP/UBXN4/PSMD2/USP14/SVIP/ANKRD9/PSMC2/SIAH1/UBXN2A/PARK7/COMMD1/RAD23B/HSPA1A/PSMD12/SGTB/TBL1X/CDK2/CD2AP/ASCC3/SKP2/VCP/PLK2/GABARAP/HUWE1/DNAJB14/DNAJB9/UBE4B	52
GO:0007517	muscle organ development	42/2053	327/18722	0.156767561015271	0.325581642814685	TGFB1/MEF2C/VAMP5/FOS/GPX1/LRP2/DSP/HIVEP3/CXCL10/GPCPD1/MEF2A/DAG1/SERP1/LAMA5/FHL3/CENPF/ENG/NOTCH1/NR2F2/NR4A1/BTG2/HBEGF/UQCC2/ISL1/RHOA/MYL6/ASS1/ID3/KLF5/ARID5B/FOXO4/SGCE/GPC1/DMD/FKBP1A/ATF3/FOXC1/TGFBR3/EID2/BASP1/HOMER1/MAPK14	42
GO:0035637	multicellular organismal signaling	22/2053	160/18722	0.157159658190291	0.326283027384687	TYMP/FLNA/SLC8A1/DSP/MEF2A/SOD1/ATP2B1/KCNQ1/DSG2/GJA1/CAMK2D/KCNE3/CNTNAP2/GJA5/ISL1/DSC2/CALM2/ANK3/JAM3/YWHAE/SLC9A1/AKAP9	22
GO:0016358	dendrite development	32/2053	243/18722	0.157733295204671	0.327360695685931	LST1/PHACTR1/MEF2C/ABI3/LRRK2/DOCK10/APP/MEF2A/PREX1/CAMK1D/CAMK1/BMP7/ITGB1/ID1/EZH2/TPBG/NRP1/KLF7/RHOA/ACTR2/HDAC2/ACSL4/DLG5/EFNA1/OBSL1/RERE/PICALM/PLK2/PTN/CFL1/COBL/DYNLT1	32
GO:0016573	histone acetylation	21/2053	152/18722	0.158526617564114	0.328893397435922	SPI1/IL1B/MORF4L2/BRCA1/SET/CHEK1/HAT1/ISL1/BRD7/GATA3/BRCA2/POLE3/EID1/USP22/PARK7/ZNF451/PHF20/YEATS4/ACTL6A/RPS6KA5/MBD3	21
GO:0051480	regulation of cytosolic calcium ion concentration	45/2053	353/18722	0.159447362346331	0.330689310085718	PTPRC/CXCR4/CD52/CORO1A/CCL3/CYBA/FPR1/C5AR1/LYN/FPR3/SLC8A1/C3AR1/GPR65/HMGB1/JAK2/LPAR6/CCR1/CD36/CCR2/PTGER4/CXCL10/CD24/S1PR4/TGM2/PTPN6/CCRL2/ATP2B1/PTK2B/TRPV2/P2RX7/GNA15/CYSLTR1/GJA1/CX3CR1/CAMK2D/TRPM2/CALM2/MCOLN3/ITGAV/FIS1/YWHAE/DMD/FKBP1A/C1QTNF1/UBASH3B	45
GO:0006333	chromatin assembly or disassembly	24/2053	177/18722	0.160903590127386	0.333594174417526	NASP/HMGB1/HMGB2/HELLS/DNAJC9/CENPW/SUPT16H/NPM1/ASF1B/SET/NAP1L1/RBBP4/MCM2/HAT1/BAZ1B/ITGB3BP/HMGA1/SMARCC1/CHAF1A/MIS18A/HIRIP3/TLK1/NAP1L4/SMARCA5	24
GO:0014743	regulation of muscle hypertrophy	11/2053	72/18722	0.161324737216653	0.334120960752474	TNFRSF1B/PARP1/MEF2A/NOTCH1/HAMP/CAMK2D/IL6ST/PARP2/RGS2/SLC9A1/LMNA	11
GO:0042246	tissue regeneration	11/2053	72/18722	0.161324737216653	0.334120960752474	CD9/GPX1/RUNX1/DAG1/NOTCH1/EZH2/YAP1/KLF5/CDKN1A/MDK/PTN	11
GO:0055021	regulation of cardiac muscle tissue growth	11/2053	72/18722	0.161324737216653	0.334120960752474	MEF2C/RUNX1/CDK1/NOTCH1/HAMP/GJA1/YAP1/PARP2/RGS2/TGFBR3/MAPK14	11
GO:0030111	regulation of Wnt signaling pathway	42/2053	328/18722	0.161664640482415	0.334363064382776	ZEB2/TGFB1/TLR2/EGFR/LRRK2/TNFAIP3/APP/WLS/PFDN5/NOTCH1/HHEX/RPS12/NOTUM/RNF43/LGR5/ASPM/KANK1/TPBG/FERMT1/ATP6V1C2/RNF213/SULF2/ISL1/SIAH2/SOX4/FOLR1/PLPP3/LGR4/YAP1/HMGXB4/TLE1/TBL1X/GLI3/STK4/VCP/MDK/CTNND1/MBD2/ZNRF3/PTPRU/MAPK14/GPC3	42
GO:0098657	import into cell	30/2053	227/18722	0.161917096854857	0.334363064382776	SLC2A3/SLC8A1/IL10RA/ACTB/LRP2/CD36/ITGA4/SLC2A1/SLC27A2/SLC38A1/ITGB1/TREM2/KCNQ1/LRRC8C/TRPV2/SLC39A10/SLC29A1/SLC15A3/SLC6A6/TRPM2/SLC6A4/SLC1A5/FOLR1/SLC19A1/RGS2/SLC9A1/PARK7/DLG1/SLC3A2/SLC1A3	30
GO:0001662	behavioral fear response	6/2053	34/18722	0.16271668466763	0.334363064382776	MEF2C/DPP4/GJA1/VDAC1/MDK/EIF4G1	6
GO:0010661	positive regulation of muscle cell apoptotic process	6/2053	34/18722	0.16271668466763	0.334363064382776	SOD2/CAMK2D/CDKN2A/BNIP3/STK4/PPARG	6
GO:0048261	negative regulation of receptor-mediated endocytosis	6/2053	34/18722	0.16271668466763	0.334363064382776	LRPAP1/APOC1/RIN3/ITGAV/SDCBP/PICALM	6
GO:0050931	pigment cell differentiation	6/2053	34/18722	0.16271668466763	0.334363064382776	ZEB2/RAB32/MEF2C/CD63/GNA11/GLI3	6
GO:1901264	carbohydrate derivative transport	12/2053	80/18722	0.162845531042695	0.334363064382776	NPC2/PSAP/SLC25A5/LRRC8C/SLC29A1/GJA1/SLC15A3/SLC35B4/SLC25A4/SLC19A1/SLC25A17/SLC25A6	12
GO:0030857	negative regulation of epithelial cell differentiation	8/2053	49/18722	0.163251149258681	0.334363064382776	VEGFA/STAT1/NOTCH1/CCND1/ID1/EZH2/YAP1/TBX3	8
GO:0042304	regulation of fatty acid biosynthetic process	8/2053	49/18722	0.163251149258681	0.334363064382776	CD74/IL1B/PDK4/BRCA1/ACADVL/APOC1/FABP5/MID1IP1	8
GO:0043330	response to exogenous dsRNA	8/2053	49/18722	0.163251149258681	0.334363064382776	IFIT1/IRAK3/COLEC12/NFKBIA/RALB/DDX1/DDX58/SLC3A2	8
GO:1901799	negative regulation of proteasomal protein catabolic process	8/2053	49/18722	0.163251149258681	0.334363064382776	HSP90AB1/PBK/SMARCC1/SDCBP/USP14/SVIP/PARK7/ALAD	8
GO:0010633	negative regulation of epithelial cell migration	16/2053	112/18722	0.163536139962513	0.334363064382776	TGFB1/MEF2C/HMGB1/KLF4/TNF/SERPINF1/VASH1/NOTCH1/NR2F2/TACSTD2/RHOA/MARVELD3/RGCC/SP100/CORO1C/PPARG	16
GO:0035601	protein deacylation	16/2053	112/18722	0.163536139962513	0.334363064382776	FLNA/LRRK2/VEGFA/BCL6/NOTUM/MORF4L2/PPT1/CAMK2D/JDP2/HDAC2/BEX4/PHB/TBL1X/ING2/RCOR1/NCAPG2	16
GO:0002551	mast cell chemotaxis	3/2053	13/18722	0.163893628724958	0.334363064382776	RAC2/VEGFA/RIN3	3
GO:0006000	fructose metabolic process	3/2053	13/18722	0.163893628724958	0.334363064382776	FBP1/AKR1B1/ALDOA	3
GO:0010635	regulation of mitochondrial fusion	3/2053	13/18722	0.163893628724958	0.334363064382776	BNIP3/TFRC/HUWE1	3
GO:0010745	negative regulation of macrophage derived foam cell differentiation	3/2053	13/18722	0.163893628724958	0.334363064382776	NFKBIA/ITGAV/PPARG	3
GO:0016322	neuron remodeling	3/2053	13/18722	0.163893628724958	0.334363064382776	APP/C3/C1QA	3
GO:0021794	thalamus development	3/2053	13/18722	0.163893628724958	0.334363064382776	UQCRQ/CNTNAP2/PTN	3
GO:0030497	fatty acid elongation	3/2053	13/18722	0.163893628724958	0.334363064382776	HACD3/TECR/HACD4	3
GO:0031053	primary miRNA processing	3/2053	13/18722	0.163893628724958	0.334363064382776	LIN28B/STAT3/HNRNPA2B1	3
GO:0031392	regulation of prostaglandin biosynthetic process	3/2053	13/18722	0.163893628724958	0.334363064382776	CD74/IL1B/FABP5	3
GO:0032530	regulation of microvillus organization	3/2053	13/18722	0.163893628724958	0.334363064382776	TWF2/KLF5/EZR	3
GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway	3/2053	13/18722	0.163893628724958	0.334363064382776	PARP1/YAP1/SKP2	3
GO:0035745	T-helper 2 cell cytokine production	3/2053	13/18722	0.163893628724958	0.334363064382776	NLRP3/RSAD2/GATA3	3
GO:0042308	negative regulation of protein import into nucleus	3/2053	13/18722	0.163893628724958	0.334363064382776	CD36/FERMT1/CHP1	3
GO:0042541	hemoglobin biosynthetic process	3/2053	13/18722	0.163893628724958	0.334363064382776	KLF4/SLC25A37/EIF2AK1	3
GO:0042761	very long-chain fatty acid biosynthetic process	3/2053	13/18722	0.163893628724958	0.334363064382776	HACD3/TECR/HACD4	3
GO:0043247	telomere maintenance in response to DNA damage	3/2053	13/18722	0.163893628724958	0.334363064382776	APEX1/ERCC1/RIF1	3
GO:0048302	regulation of isotype switching to IgG isotypes	3/2053	13/18722	0.163893628724958	0.334363064382776	PTPRC/IL27RA/MSH2	3
GO:0051709	regulation of killing of cells of other organism	3/2053	13/18722	0.163893628724958	0.334363064382776	CLEC7A/SYK/P2RX7	3
GO:0060707	trophoblast giant cell differentiation	3/2053	13/18722	0.163893628724958	0.334363064382776	SOCS3/NR2F2/E2F7	3
GO:0061000	negative regulation of dendritic spine development	3/2053	13/18722	0.163893628724958	0.334363064382776	HDAC2/EFNA1/PLK2	3
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	3/2053	13/18722	0.163893628724958	0.334363064382776	VEGFA/NOTCH1/BACH1	3
GO:0070914	UV-damage excision repair	3/2053	13/18722	0.163893628724958	0.334363064382776	DDB1/POLD3/ERCC1	3
GO:0071696	ectodermal placode development	3/2053	13/18722	0.163893628724958	0.334363064382776	NRP1/HDAC2/TBX3	3
GO:0072710	response to hydroxyurea	3/2053	13/18722	0.163893628724958	0.334363064382776	RAD51/BLM/TIMELESS	3
GO:0098814	spontaneous synaptic transmission	3/2053	13/18722	0.163893628724958	0.334363064382776	APP/NSG1/ITGB1	3
GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	3/2053	13/18722	0.163893628724958	0.334363064382776	PLXNC1/NRP2/NRP1	3
GO:1904590	negative regulation of protein import	3/2053	13/18722	0.163893628724958	0.334363064382776	CD36/FERMT1/CHP1	3
GO:1904925	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	3/2053	13/18722	0.163893628724958	0.334363064382776	HK2/VPS13C/HUWE1	3
GO:1905269	positive regulation of chromatin organization	3/2053	13/18722	0.163893628724958	0.334363064382776	DNMT1/TPR/TRIM28	3
GO:1905907	negative regulation of amyloid fibril formation	3/2053	13/18722	0.163893628724958	0.334363064382776	PFDN5/TREM2/PFDN1	3
GO:2000551	regulation of T-helper 2 cell cytokine production	3/2053	13/18722	0.163893628724958	0.334363064382776	NLRP3/RSAD2/GATA3	3
GO:0034620	cellular response to unfolded protein	14/2053	96/18722	0.164019919514196	0.33450697385628	HSPD1/SERP1/HSPA5/CCND1/HSPA8/HSPA6/HSPA14/HSPA1A/PPP1R15A/ATF3/VCP/HSPA9/TM7SF3/DNAJB9	14
GO:0031345	negative regulation of cell projection organization	25/2053	186/18722	0.165803124350183	0.338028795820964	VIM/LGALS1/FLNA/B2M/ABI3/SPP1/LRRK2/CTSZ/SEMA4A/ARHGAP4/SEMA6A/ID1/KANK1/TACSTD2/ITM2C/NRP1/RHOA/CIB1/HDAC2/SEMA6D/EFNA1/YAP1/CCP110/ODF2L/MYLIP	25
GO:0071331	cellular response to hexose stimulus	21/2053	153/18722	0.165862060508705	0.338034090710677	HLA-DRB1/LGALS1/CYBA/UCP2/SERPINF1/MPC2/TREM2/ICAM1/SLC29A1/HMGN3/KLF7/SOX4/GCLM/LRP5/FIS1/PHPT1/BAD/IGF1R/TRA2B/NME1/CCDC186	21
GO:0060828	regulation of canonical Wnt signaling pathway	33/2053	253/18722	0.166952596936112	0.340141114301077	ZEB2/TGFB1/EGFR/LRRK2/WLS/PFDN5/NOTCH1/HHEX/RPS12/NOTUM/LGR5/ASPM/KANK1/TPBG/FERMT1/SULF2/ISL1/SIAH2/SOX4/FOLR1/LGR4/YAP1/TLE1/TBL1X/GLI3/STK4/VCP/MDK/CTNND1/ZNRF3/PTPRU/MAPK14/GPC3	33
GO:0007026	negative regulation of microtubule depolymerization	5/2053	27/18722	0.167567004577438	0.340446771956824	CIB1/TPX2/CKAP2/MID1IP1/ARHGEF2	5
GO:0007263	nitric oxide mediated signal transduction	5/2053	27/18722	0.167567004577438	0.340446771956824	FPR1/EGFR/VEGFA/CD36/DDAH2	5
GO:0010586	miRNA metabolic process	5/2053	27/18722	0.167567004577438	0.340446771956824	LIN28B/HRAS/KHSRP/SND1/AGO2	5
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	5/2053	27/18722	0.167567004577438	0.340446771956824	SLC8A1/CAMK2D/CALM2/SLC9A1/DMD	5
GO:0018126	protein hydroxylation	5/2053	27/18722	0.167567004577438	0.340446771956824	P4HB/PRDX4/ASPH/PLOD2/P3H1	5
GO:0018904	ether metabolic process	5/2053	27/18722	0.167567004577438	0.340446771956824	LPCAT2/ALOX5/PLA2G7/CHPT1/TXN	5
GO:0033688	regulation of osteoblast proliferation	5/2053	27/18722	0.167567004577438	0.340446771956824	HPSE/RHOA/ITGAV/LRP5/ATRAID	5
GO:0006754	ATP biosynthetic process	9/2053	57/18722	0.167670035188736	0.340446771956824	TMSB4X/TGFB1/PARP1/TREM2/ALDOA/STAT3/STOML2/VCP/PRKAG2	9
GO:0051289	protein homotetramerization	9/2053	57/18722	0.167670035188736	0.340446771956824	SAMHD1/B2M/GBP5/SOD2/VASP/TK1/ALDOA/TRPM2/SHMT1	9
GO:0051785	positive regulation of nuclear division	9/2053	57/18722	0.167670035188736	0.340446771956824	IL1B/RAD51AP1/NUSAP1/ANAPC11/CDT1/SPHK1/RGCC/LRP5/INSR	9
GO:0006109	regulation of carbohydrate metabolic process	24/2053	178/18722	0.16773949293525	0.340472583765731	PLEK/TGFB1/HMGB1/FBP1/PHLDA2/APP/PGP/PTAFR/PTK2B/PDK4/P2RX7/DDIT4/SLC2A6/SLC35B4/PMAIP1/DDB1/STAT3/ARL2/BAD/MIDN/C1QTNF1/LCMT1/INSR/PRKAG2	24
GO:0010977	negative regulation of neuron projection development	19/2053	137/18722	0.168824553767759	0.341935168522337	VIM/LGALS1/FLNA/B2M/SPP1/LRRK2/CTSZ/SEMA4A/ARHGAP4/SEMA6A/KANK1/ITM2C/NRP1/RHOA/CIB1/HDAC2/SEMA6D/EFNA1/MYLIP	19
GO:0000272	polysaccharide catabolic process	4/2053	20/18722	0.169485865197571	0.341935168522337	HMGB1/AOAH/AGL/GAA	4
GO:0002115	store-operated calcium entry	4/2053	20/18722	0.169485865197571	0.341935168522337	CD84/HOMER3/ORAI2/HOMER1	4
GO:0003215	cardiac right ventricle morphogenesis	4/2053	20/18722	0.169485865197571	0.341935168522337	NOTCH1/ISL1/SOX4/GATA3	4
GO:0006525	arginine metabolic process	4/2053	20/18722	0.169485865197571	0.341935168522337	SLC7A7/DDAH2/OAT/ASS1	4
GO:0007194	negative regulation of adenylate cyclase activity	4/2053	20/18722	0.169485865197571	0.341935168522337	CCR2/P2RY13/GNAI2/AKAP9	4
GO:0009713	catechol-containing compound biosynthetic process	4/2053	20/18722	0.169485865197571	0.341935168522337	NR4A2/GATA3/PARK7/GCH1	4
GO:0010801	negative regulation of peptidyl-threonine phosphorylation	4/2053	20/18722	0.169485865197571	0.341935168522337	DDIT4/CALM2/PARD3/EIF4G1	4
GO:0031498	chromatin disassembly	4/2053	20/18722	0.169485865197571	0.341935168522337	SUPT16H/SET/HMGA1/SMARCC1	4
GO:0039535	regulation of RIG-I signaling pathway	4/2053	20/18722	0.169485865197571	0.341935168522337	OASL/BIRC3/C1QBP/USP15	4
GO:0042423	catecholamine biosynthetic process	4/2053	20/18722	0.169485865197571	0.341935168522337	NR4A2/GATA3/PARK7/GCH1	4
GO:0045063	T-helper 1 cell differentiation	4/2053	20/18722	0.169485865197571	0.341935168522337	HMGB1/STAT6/SEMA4A/SPN	4
GO:0046931	pore complex assembly	4/2053	20/18722	0.169485865197571	0.341935168522337	P2RX7/TMEM170A/BAD/CCT8	4
GO:0061318	renal filtration cell differentiation	4/2053	20/18722	0.169485865197571	0.341935168522337	CD24/NOTCH2/BASP1/ASXL1	4
GO:0071243	cellular response to arsenic-containing substance	4/2053	20/18722	0.169485865197571	0.341935168522337	HMOX1/HNRNPA1/ATF3/VCP	4
GO:0072112	glomerular visceral epithelial cell differentiation	4/2053	20/18722	0.169485865197571	0.341935168522337	CD24/NOTCH2/BASP1/ASXL1	4
GO:0090201	negative regulation of release of cytochrome c from mitochondria	4/2053	20/18722	0.169485865197571	0.341935168522337	GPX1/ARRB2/TRIAP1/LMNA	4
GO:1902004	positive regulation of amyloid-beta formation	4/2053	20/18722	0.169485865197571	0.341935168522337	TNF/EFNA1/IFNGR1/PICALM	4
GO:0007498	mesoderm development	18/2053	129/18722	0.170145091862471	0.343149765100783	HCK/KLF4/SECTM1/JAK2/VEGFA/WLS/BTK/MEST/BMP7/ITGB1/ITGB4/ZFP36L1/IKZF1/GJA1/YAP1/FOXC1/KDM6B/TBX3	18
GO:0030705	cytoskeleton-dependent intracellular transport	26/2053	195/18722	0.170442187367957	0.343525671790609	MYO1F/MYO1G/TUBA1A/SYNE2/TUBA1B/TUBB/APP/SOD1/TUBA1C/HSPB11/CCDC88A/UBB/HSPA8/CCDC88B/MYO1C/ARMCX3/FNBP1L/HOOK2/ARHGAP21/MYO5A/LRPPRC/KIF4A/PURA/CCDC186/ACTN4/MYO7A	26
GO:0043489	RNA stabilization	10/2053	65/18722	0.170560496044037	0.343525671790609	SLC11A1/ZFP36/FUS/PABPC1/HNRNPD/MYD88/HNRNPA0/E2F1/YBX1/MAPK14	10
GO:0060389	pathway-restricted SMAD protein phosphorylation	10/2053	65/18722	0.170560496044037	0.343525671790609	TGFB1/BMP7/ENG/LDLRAD4/RBPMS/USP15/SDCBP/TTK/TGFBR3/PPARG	10
GO:0070936	protein K48-linked ubiquitination	10/2053	65/18722	0.170560496044037	0.343525671790609	TNFAIP3/UBE2T/PPIA/IFI27/UBE2C/UBE2D1/DTX3L/RNF8/SKP2/GABARAP	10
GO:0007212	dopamine receptor signaling pathway	7/2053	42/18722	0.171352525668723	0.344427187273815	FLNA/LRRK2/GNAS/ARRB2/NSG1/GNA15/GNA11	7
GO:0010591	regulation of lamellipodium assembly	7/2053	42/18722	0.171352525668723	0.344427187273815	WAS/RAC2/ABI3/ACTR2/TWF2/ACTR3/WASF2	7
GO:0010939	regulation of necrotic cell death	7/2053	42/18722	0.171352525668723	0.344427187273815	TSPO/BIRC3/SLC6A6/SLC25A4/HEBP2/ARHGEF2/BNIP3	7
GO:0014912	negative regulation of smooth muscle cell migration	7/2053	42/18722	0.171352525668723	0.344427187273815	AIF1/MEF2C/GSTP1/TRIB1/RHOA/SEMA6D/APEX1	7
GO:0035019	somatic stem cell population maintenance	7/2053	42/18722	0.171352525668723	0.344427187273815	SPI1/ZFP36L2/BMP7/ASCL2/SOX4/LRP5/YAP1	7
GO:0043507	positive regulation of JUN kinase activity	7/2053	42/18722	0.171352525668723	0.344427187273815	TNF/FGD2/RPS3/TLR6/SYK/PTK2B/MAP3K4	7
GO:0050890	cognition	38/2053	296/18722	0.171446220320787	0.344500107811361	HLA-DRA/C5AR1/LILRB2/B2M/MEF2C/TLR2/FOS/EGFR/TNF/SERPINF1/APP/CEBPB/SGK1/FEN1/TUSC3/MME/C12orf57/ITGB1/TREM2/COMT/PPT1/BTG2/CX3CR1/TPBG/CNTNAP2/SLC6A4/ACTR2/VDAC1/NRGN/EIF2AK4/JUN/PAK6/INSR/MDK/PICALM/PLK2/PTN/MEIS2	38
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	11/2053	73/18722	0.172349018684333	0.346198229697355	NCF1/PLAUR/EGFR/IFI6/RHBDF2/CCDC88A/HBEGF/DGKD/MVP/VPS25/PTPN3	11
GO:0000041	transition metal ion transport	15/2053	105/18722	0.173085786673946	0.347561820630413	SLC11A1/B2M/FTH1/FTL/SLC40A1/SLC25A37/TCN2/HAMP/SLC39A10/SLC39A1/TRPM2/SLC39A7/PGRMC2/TFRC/COX17	15
GO:0071326	cellular response to monosaccharide stimulus	21/2053	154/18722	0.173377153233838	0.348030418000344	HLA-DRB1/LGALS1/CYBA/UCP2/SERPINF1/MPC2/TREM2/ICAM1/SLC29A1/HMGN3/KLF7/SOX4/GCLM/LRP5/FIS1/PHPT1/BAD/IGF1R/TRA2B/NME1/CCDC186	21
GO:0070252	actin-mediated cell contraction	14/2053	97/18722	0.173566464141725	0.348173283886291	FLNA/DSP/KCNQ1/EMP2/DSG2/GJA1/CAMK2D/KCNE3/GJA5/DSC2/MYL6/SLC9A1/DLG1/AKAP9	14
GO:0010657	muscle cell apoptotic process	13/2053	89/18722	0.173680439778611	0.348173283886291	SOD2/JAK2/HMOX1/ARRB2/DNMT1/BMP7/PTK2B/CAMK2D/CDKN2A/BNIP3/STK4/MDK/PPARG	13
GO:0046330	positive regulation of JNK cascade	13/2053	89/18722	0.173680439778611	0.348173283886291	NCF1/PYCARD/HMGB1/TNF/TLR4/IL1B/APP/GADD45B/PTK2B/HRAS/SDCBP/MYD88/RASSF2	13
GO:0051781	positive regulation of cell division	13/2053	89/18722	0.173680439778611	0.348173283886291	TGFB1/VEGFA/IL1B/CDC6/RHOA/KIF23/KIF20B/ECT2/AURKB/MDK/PTN/PDGFA/YBX1	13
GO:0001936	regulation of endothelial cell proliferation	24/2053	179/18722	0.174730815546231	0.350148750186197	CYBA/MEF2C/HMGB1/VEGFA/ALOX5/TNF/HMGB2/ITGA4/STAT1/HMOX1/NRP2/VASH1/NR2F2/TNFSF12/NR4A1/STAT5A/FLT1/GJA1/NRP1/STAT3/MYDGF/RGCC/MDK/PPARG	24
GO:0071383	cellular response to steroid hormone stimulus	27/2053	204/18722	0.174840942592974	0.350148750186197	ZFP36/ZFP36L2/EGFR/JAK2/PARP1/SERPINF1/GSTP1/BMP7/CALR/ZFP36L1/ATP2B1/ICAM1/BRCA1/DDIT4/PHB2/ISL1/RHOA/ASS1/NCOR2/YAP1/ABHD2/PHB/PGRMC2/PARK7/SKP2/PKN1/URI1	27
GO:1901888	regulation of cell junction assembly	27/2053	204/18722	0.174840942592974	0.350148750186197	MEF2C/TLR2/ABI3/VEGFA/TNF/IL1B/APP/GPBAR1/SEMA4A/GJA1/TPBG/CNTNAP2/S100A10/LIMS1/NRP1/RHOA/DLG5/MYO1C/TJP1/RAP1A/FERMT2/SLC9A1/VCL/CORO1C/PTK2/EIF4G1/CLSTN1	27
GO:0003007	heart morphogenesis	32/2053	246/18722	0.175261384606047	0.350873642854949	TGFB1/FLNA/MEF2C/VEGFA/LRP2/DSP/NRP2/BMP7/ENG/NOTCH1/ADAMTS1/GJA5/NRP1/ISL1/NOTCH2/SOX4/AHI1/GATA3/EPHB4/FOLR1/EFNA1/YAP1/FHL2/GAA/FKBP1A/FOXC1/INSR/TGFBR3/PTK2/TBX3/ADGRG6/ASXL1	32
GO:0021700	developmental maturation	36/2053	280/18722	0.176607565380211	0.35345076460349	CLEC7A/RAB32/LYL1/LRRK2/VEGFA/SNX10/TYMS/KLF2/NR4A2/APP/C3/BTK/DAG1/C1QA/PTK2B/CX3CR1/CNTNAP2/AKR1B1/FERMT1/EPAS1/RHOA/FAM210B/FBXO5/GATA3/CD63/BRCA2/ABHD2/PFN1/CDKN1A/RERE/TFCP2L1/PICALM/DEFB1/CLSTN1/PPARG/RAC3	36
GO:0050873	brown fat cell differentiation	8/2053	50/18722	0.176920771213489	0.353723634548796	PLAC8/METRNL/CEBPB/BMP7/ADRB1/RGS2/BNIP3/MAPK14	8
GO:1903747	regulation of establishment of protein localization to mitochondrion	8/2053	50/18722	0.176920771213489	0.353723634548796	RAC2/LRRK2/LMAN1/BNIP3L/PDCD5/SAE1/NMT1/HUWE1	8
GO:2000677	regulation of transcription regulatory region DNA binding	8/2053	50/18722	0.176920771213489	0.353723634548796	TMSB4X/TGFB1/KLF4/PARP1/GATA3/MSX2/PARK7/FOXC1	8
GO:0007611	learning or memory	33/2053	255/18722	0.178683119971915	0.356983984680633	LILRB2/B2M/MEF2C/TLR2/FOS/EGFR/SERPINF1/APP/CEBPB/SGK1/FEN1/MME/ITGB1/TREM2/COMT/PPT1/BTG2/CX3CR1/TPBG/CNTNAP2/SLC6A4/ACTR2/VDAC1/NRGN/EIF2AK4/JUN/PAK6/INSR/MDK/PICALM/PLK2/PTN/MEIS2	33
GO:0001569	branching involved in blood vessel morphogenesis	6/2053	35/18722	0.179384452302018	0.356983984680633	VEGFA/ENG/NRP1/COL4A1/STK4/MDK	6
GO:0002209	behavioral defense response	6/2053	35/18722	0.179384452302018	0.356983984680633	MEF2C/DPP4/GJA1/VDAC1/MDK/EIF4G1	6
GO:0006471	protein ADP-ribosylation	6/2053	35/18722	0.179384452302018	0.356983984680633	PARP1/PARP9/PARP2/PNKP/PARP14/PARP12	6
GO:0010765	positive regulation of sodium ion transport	6/2053	35/18722	0.179384452302018	0.356983984680633	GLRX/CHP1/ANK3/SLC9A1/DMD/ACTN4	6
GO:0010837	regulation of keratinocyte proliferation	6/2053	35/18722	0.179384452302018	0.356983984680633	ZFP36/ZFP36L1/NOTCH2/VDR/YAP1/MDK	6
GO:0032814	regulation of natural killer cell activation	6/2053	35/18722	0.179384452302018	0.356983984680633	TYROBP/HLA-F/HLA-E/HAVCR2/FGR/IL18	6
GO:0033146	regulation of intracellular estrogen receptor signaling pathway	6/2053	35/18722	0.179384452302018	0.356983984680633	PARP1/BRCA1/PHB2/ISL1/YAP1/SKP2	6
GO:0034405	response to fluid shear stress	6/2053	35/18722	0.179384452302018	0.356983984680633	MEF2C/KLF4/KLF2/PTK2B/GJA1/ASS1	6
GO:0043243	positive regulation of protein-containing complex disassembly	6/2053	35/18722	0.179384452302018	0.356983984680633	PLEK/TNF/DSTN/IGF1R/BNIP3/INSR	6
GO:0048821	erythrocyte development	6/2053	35/18722	0.179384452302018	0.356983984680633	NCKAP1L/KLF2/BCL6/SH2B3/FAM210B/RPS6	6
GO:0070536	protein K63-linked deubiquitination	6/2053	35/18722	0.179384452302018	0.356983984680633	TNFAIP3/USP27X/PSMD14/VCP/DESI2/BRCC3	6
GO:0086005	ventricular cardiac muscle cell action potential	6/2053	35/18722	0.179384452302018	0.356983984680633	DSP/KCNQ1/DSG2/KCNE3/DSC2/DLG1	6
GO:0098801	regulation of renal system process	6/2053	35/18722	0.179384452302018	0.356983984680633	CYBA/EMP2/COMT/GJA1/GNAI2/GJA5	6
GO:0031109	microtubule polymerization or depolymerization	17/2053	122/18722	0.179989305055335	0.357950225499506	STMN1/RPS3/MET/CLIP1/CIB1/FBXO5/TPX2/CKAP2/ARL2/MID1IP1/SKA2/ARHGEF2/HSPA1A/CENPJ/SKA3/AKAP9/DRG1	17
GO:0051928	positive regulation of calcium ion transport	17/2053	122/18722	0.179989305055335	0.357950225499506	TSPO/CCL3/CCL4/CCR1/ARRB2/CXCL10/LILRA2/LILRA5/LGALS3/ATP2B1/TRPV2/P2RX7/VMP1/KCNE3/CALM2/SLC9A1/HOMER1	17
GO:0006826	iron ion transport	9/2053	58/18722	0.18045928954563	0.358647147159251	SLC11A1/B2M/FTH1/FTL/SLC40A1/SLC25A37/HAMP/PGRMC2/TFRC	9
GO:0007405	neuroblast proliferation	9/2053	58/18722	0.18045928954563	0.358647147159251	LRRK2/VEGFA/NOTCH1/ASPM/CX3CR1/ARHGEF2/GLI3/NUMB/PTN	9
GO:0021987	cerebral cortex development	16/2053	114/18722	0.181334380484556	0.360266981095144	BCL2A1/FLNA/PHACTR1/SLC2A1/ADGRG1/LAMB1/ASPM/CNTNAP2/RHOA/GNG12/TACC2/BAD/BNIP3/TRA2B/GLI3/MDK	16
GO:0002793	positive regulation of peptide secretion	15/2053	106/18722	0.182484109646049	0.362289485989773	S100A8/HLA-DRB1/EGFR/JAK2/GLUL/MPC2/SERP1/GJA1/TRPM2/ISL1/SOX4/ACSL4/PHPT1/BAD/TM7SF3	15
GO:0050922	negative regulation of chemotaxis	10/2053	66/18722	0.182593900938846	0.362289485989773	AIF1/DUSP1/GSTP1/DPP4/SEMA4A/NOTCH1/SEMA6A/NRP1/RIN3/SEMA6D	10
GO:0051893	regulation of focal adhesion assembly	10/2053	66/18722	0.182593900938846	0.362289485989773	VEGFA/S100A10/LIMS1/NRP1/RHOA/FERMT2/SLC9A1/VCL/CORO1C/PTK2	10
GO:0090109	regulation of cell-substrate junction assembly	10/2053	66/18722	0.182593900938846	0.362289485989773	VEGFA/S100A10/LIMS1/NRP1/RHOA/FERMT2/SLC9A1/VCL/CORO1C/PTK2	10
GO:0016331	morphogenesis of embryonic epithelium	20/2053	147/18722	0.183119112135058	0.363211462086066	TGFB1/SPINT1/SPINT2/LRP2/VASP/RPS7/RARA/BMP7/LAMA5/LMO4/TFAP2A/SOX4/GATA3/FOLR1/KIF20B/PFN1/LUZP1/STK4/IRX2/COBL	20
GO:0003333	amino acid transmembrane transport	14/2053	98/18722	0.183383582679049	0.363615828180533	SLC7A7/SLC38A1/ITGB1/LRRC8C/SLC6A6/SLC1A5/SFXN3/SFXN1/RGS2/SLC7A6/SLC38A9/SLC38A6/SLC3A2/SLC1A3	14
GO:0048844	artery morphogenesis	11/2053	74/18722	0.183724459633433	0.36417137687499	VEGFA/LRP2/ENG/NOTCH1/HPGD/GJA5/NRP1/SOX4/FOLR1/FOXC1/MDK	11
GO:0030901	midbrain development	13/2053	90/18722	0.183960547879658	0.364350111388915	ACTB/MBP/NR4A2/WLS/HSPA5/UQCRQ/RHOA/CALM2/DLG5/CCDC14/YWHAE/GNB4/BASP1	13
GO:0061097	regulation of protein tyrosine kinase activity	13/2053	90/18722	0.183960547879658	0.364350111388915	PTPRC/NCF1/FCGR1A/CSF1R/LILRB4/APP/CD24/LILRA5/HBEGF/EFNA1/MVP/VPS25/NCAPG2	13
GO:0016575	histone deacetylation	12/2053	82/18722	0.184118256288532	0.364350111388915	LRRK2/VEGFA/BCL6/MORF4L2/CAMK2D/JDP2/HDAC2/PHB/TBL1X/ING2/RCOR1/NCAPG2	12
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	12/2053	82/18722	0.184118256288532	0.364350111388915	RPS21/FEN1/RNASET2/POP7/RNASEH2A/TSEN34/SND1/APEX1/AGO2/EXO1/LACTB2/BMS1	12
GO:1905897	regulation of response to endoplasmic reticulum stress	12/2053	82/18722	0.184118256288532	0.364350111388915	LRRK2/ALOX5/HSPA5/ERP29/PMAIP1/USP14/SVIP/MANF/PARK7/HSPA1A/PPP1R15A/DNAJB9	12
GO:1903522	regulation of blood circulation	33/2053	256/18722	0.18471261301172	0.36540576263446	FLNA/SLC8A1/EGFR/JAK2/CELF2/DSP/DOCK4/MEF2A/TBXAS1/ATP2B1/KCNQ1/DSG2/ICAM1/GJA1/HBEGF/CAMK2D/HRH2/KCNE3/EPAS1/GJA5/ADRB1/ISL1/DSC2/RHOA/CALM2/YWHAE/RGS2/SLC9A1/GCH1/DLG1/DMD/GAA/AKAP9	33
GO:0045776	negative regulation of blood pressure	7/2053	43/18722	0.186635945438998	0.36822531651666	SOD2/PTAFR/KCNK6/GJA5/ADRB1/SCPEP1/GCH1	7
GO:0045981	positive regulation of nucleotide metabolic process	7/2053	43/18722	0.186635945438998	0.36822531651666	TMSB4X/APP/TREM2/P2RX7/STAT3/INSR/VCP	7
GO:1900544	positive regulation of purine nucleotide metabolic process	7/2053	43/18722	0.186635945438998	0.36822531651666	TMSB4X/APP/TREM2/P2RX7/STAT3/INSR/VCP	7
GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	7/2053	43/18722	0.186635945438998	0.36822531651666	MEF2C/SOD2/GSTP1/HMOX1/RHOA/CDKN1A/PPARG	7
GO:0006516	glycoprotein catabolic process	5/2053	28/18722	0.186812977246119	0.36822531651666	CST3/CTSL/HPSE/FBXO6/GPC1	5
GO:0010464	regulation of mesenchymal cell proliferation	5/2053	28/18722	0.186812977246119	0.36822531651666	STAT1/LRP5/PTN/LMNA/PDGFA	5
GO:0010818	T cell chemotaxis	5/2053	28/18722	0.186812977246119	0.36822531651666	CCL3/CXCL16/CCR2/CXCL10/GPR183	5
GO:0010884	positive regulation of lipid storage	5/2053	28/18722	0.186812977246119	0.36822531651666	MSR1/CD36/C3/HILPDA/PLIN2	5
GO:0051894	positive regulation of focal adhesion assembly	5/2053	28/18722	0.186812977246119	0.36822531651666	VEGFA/S100A10/LIMS1/NRP1/FERMT2	5
GO:0099623	regulation of cardiac muscle cell membrane repolarization	5/2053	28/18722	0.186812977246119	0.36822531651666	FLNA/KCNQ1/KCNE3/GJA5/AKAP9	5
GO:1903649	regulation of cytoplasmic transport	5/2053	28/18722	0.186812977246119	0.36822531651666	MSN/SORL1/LRRK2/RDX/EZR	5
GO:0019827	stem cell population maintenance	18/2053	131/18722	0.187042044452587	0.368555752615935	SPI1/ZFP36L2/KLF4/BMP7/SMC3/NOTCH1/RTF1/ASPM/ASCL2/NOTCH2/STAT3/SOX4/LRP5/YAP1/GNL3/RIF1/PTN/TBX3	18
GO:0008016	regulation of heart contraction	27/2053	206/18722	0.188330191724295	0.370972143908656	FLNA/SLC8A1/JAK2/CELF2/DSP/MEF2A/ATP2B1/KCNQ1/DSG2/GJA1/HBEGF/CAMK2D/KCNE3/EPAS1/GJA5/ADRB1/ISL1/DSC2/CALM2/YWHAE/RGS2/SLC9A1/GCH1/DLG1/DMD/GAA/AKAP9	27
GO:0003231	cardiac ventricle development	17/2053	123/18722	0.188873345143877	0.371021913293113	TGFB1/MEF2C/LRP2/DSP/ENG/NOTCH1/LMO4/GJA5/ISL1/SOX4/GATA3/CNTRL/FKBP1A/LUZP1/FOXC1/TGFBR3/TBX3	17
GO:0009267	cellular response to starvation	21/2053	156/18722	0.188933322268539	0.371021913293113	UCP2/UPP1/LRRK2/IFI16/SLC2A1/GLUL/PDK4/COMT/HSPA5/CTSV/HNRNPA1/HSPA8/PMAIP1/RALB/EIF2AK4/JUN/CDKN1A/ATF3/GABARAP/WIPI2/PRKAG2	21
GO:0051209	release of sequestered calcium ion into cytosol	16/2053	115/18722	0.190580931902919	0.371021913293113	PTPRC/CORO1A/CCL3/CYBA/LYN/SLC8A1/CXCL10/PTPN6/PTK2B/CAMK2D/TRPM2/CALM2/MCOLN3/DMD/FKBP1A/UBASH3B	16
GO:0051339	regulation of lyase activity	8/2053	51/18722	0.191074833772189	0.371021913293113	CCR2/P2RY13/TIMP2/GNAI2/CAP1/PARK7/PHPT1/AKAP9	8
GO:0060043	regulation of cardiac muscle cell proliferation	8/2053	51/18722	0.191074833772189	0.371021913293113	MEF2C/RUNX1/CDK1/NOTCH1/GJA1/YAP1/TGFBR3/MAPK14	8
GO:0044272	sulfur compound biosynthetic process	20/2053	148/18722	0.191257555374421	0.371021913293113	GSTP1/SLC26A2/MPC2/ACSS1/TECR/PDK4/CHPF/PPT1/ADI1/CDO1/SLC25A1/MTAP/CHST15/ACSL4/GCLM/CHST14/DSE/PDHA1/MTR/ENOPH1	20
GO:0021761	limbic system development	15/2053	107/18722	0.192127154089199	0.371021913293113	NRP2/RARA/BTG2/EZH2/UBB/UQCRQ/CNTNAP2/NRP1/CDK6/ANXA3/GLI3/MDK/KDM6B/NME1/TBX3	15
GO:0003177	pulmonary valve development	4/2053	21/18722	0.192372637382026	0.371021913293113	TNFRSF1B/NOTCH1/GJA5/NOTCH2	4
GO:0006067	ethanol metabolic process	4/2053	21/18722	0.192372637382026	0.371021913293113	ALDH2/ACSS1/ADH5/SULT1A1	4
GO:0006123	mitochondrial electron transport, cytochrome c to oxygen	4/2053	21/18722	0.192372637382026	0.371021913293113	COX6A1/COX7A2/COX6C/COX5A	4
GO:0007350	blastoderm segmentation	4/2053	21/18722	0.192372637382026	0.371021913293113	NRP2/NRP1/BASP1/TBX3	4
GO:0010878	cholesterol storage	4/2053	21/18722	0.192372637382026	0.371021913293113	MSR1/CD36/TREM2/PPARG	4
GO:0030502	negative regulation of bone mineralization	4/2053	21/18722	0.192372637382026	0.371021913293113	SRGN/CCL3/CCR1/PTK2B	4
GO:0031145	anaphase-promoting complex-dependent catabolic process	4/2053	21/18722	0.192372637382026	0.371021913293113	ANAPC11/UBE2C/UBE2S/CDK2	4
GO:0032288	myelin assembly	4/2053	21/18722	0.192372637382026	0.371021913293113	CD9/TLR2/ITGB4/GPC1	4
GO:0034312	diol biosynthetic process	4/2053	21/18722	0.192372637382026	0.371021913293113	DHFR/SPHK1/GCH1/QDPR	4
GO:0038083	peptidyl-tyrosine autophosphorylation	4/2053	21/18722	0.192372637382026	0.371021913293113	EGFR/VEGFA/PTK2B/IGF1R	4
GO:0046597	negative regulation of viral entry into host cell	4/2053	21/18722	0.192372637382026	0.371021913293113	FCN1/IFITM2/IFITM3/CIITA	4
GO:0046599	regulation of centriole replication	4/2053	21/18722	0.192372637382026	0.371021913293113	NPM1/BRCA1/CENPJ/PLK2	4
GO:0048485	sympathetic nervous system development	4/2053	21/18722	0.192372637382026	0.371021913293113	NRP2/NRP1/SOX4/GATA3	4
GO:0050849	negative regulation of calcium-mediated signaling	4/2053	21/18722	0.192372637382026	0.371021913293113	PLEK/HOMER3/CHP1/FHL2	4
GO:0060117	auditory receptor cell development	4/2053	21/18722	0.192372637382026	0.371021913293113	SOD1/KCNQ1/TRIOBP/MYO7A	4
GO:0060972	left/right pattern formation	4/2053	21/18722	0.192372637382026	0.371021913293113	NOTCH1/HSPB11/NOTCH2/AHI1	4
GO:0072311	glomerular epithelial cell differentiation	4/2053	21/18722	0.192372637382026	0.371021913293113	CD24/NOTCH2/BASP1/ASXL1	4
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	4/2053	21/18722	0.192372637382026	0.371021913293113	VEGFA/MAGED1/TACSTD2/LGR4	4
GO:0097062	dendritic spine maintenance	4/2053	21/18722	0.192372637382026	0.371021913293113	TREM2/IGF1R/INSR/HOMER1	4
GO:1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	4/2053	21/18722	0.192372637382026	0.371021913293113	SLC25A5/CHCHD10/HSPA1A/NMT1	4
GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	4/2053	21/18722	0.192372637382026	0.371021913293113	CD74/CD44/TRIAP1/ING2	4
GO:1902473	regulation of protein localization to synapse	4/2053	21/18722	0.192372637382026	0.371021913293113	DAG1/HRAS/RAP1A/DLG1	4
GO:0002091	negative regulation of receptor internalization	3/2053	14/18722	0.192560372999126	0.371021913293113	LRPAP1/RIN3/SDCBP	3
GO:0002517	T cell tolerance induction	3/2053	14/18722	0.192560372999126	0.371021913293113	HLA-B/LILRB2/LILRB4	3
GO:0003188	heart valve formation	3/2053	14/18722	0.192560372999126	0.371021913293113	NOTCH1/GJA5/EFNA1	3
GO:0003376	sphingosine-1-phosphate receptor signaling pathway	3/2053	14/18722	0.192560372999126	0.371021913293113	S1PR4/SPHK1/EZR	3
GO:0006521	regulation of cellular amino acid metabolic process	3/2053	14/18722	0.192560372999126	0.371021913293113	SLC7A7/COMT/PARK7	3
GO:0006999	nuclear pore organization	3/2053	14/18722	0.192560372999126	0.371021913293113	TPR/TMEM170A/NUP54	3
GO:0007100	mitotic centrosome separation	3/2053	14/18722	0.192560372999126	0.371021913293113	RANBP1/CHEK1/KIF11	3
GO:0009173	pyrimidine ribonucleoside monophosphate metabolic process	3/2053	14/18722	0.192560372999126	0.371021913293113	UPP1/DPYD/UMPS	3
GO:0010989	negative regulation of low-density lipoprotein particle clearance	3/2053	14/18722	0.192560372999126	0.371021913293113	CSK/KHSRP/MYLIP	3
GO:0031650	regulation of heat generation	3/2053	14/18722	0.192560372999126	0.371021913293113	TNF/IL1B/PTGES	3
GO:0033008	positive regulation of mast cell activation involved in immune response	3/2053	14/18722	0.192560372999126	0.371021913293113	FGR/SYK/SNX4	3
GO:0034616	response to laminar fluid shear stress	3/2053	14/18722	0.192560372999126	0.371021913293113	KLF4/KLF2/ASS1	3
GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	3/2053	14/18722	0.192560372999126	0.371021913293113	PTAFR/P2RY13/P2RY11	3
GO:0035672	oligopeptide transmembrane transport	3/2053	14/18722	0.192560372999126	0.371021913293113	GJA1/SLC15A3/SLC13A3	3
GO:0036444	calcium import into the mitochondrion	3/2053	14/18722	0.192560372999126	0.371021913293113	VDAC1/AFG3L2/MCUR1	3
GO:0042415	norepinephrine metabolic process	3/2053	14/18722	0.192560372999126	0.371021913293113	AKR1B1/EPAS1/GATA3	3
GO:0043173	nucleotide salvage	3/2053	14/18722	0.192560372999126	0.371021913293113	UPP1/ADK/AMPD3	3
GO:0043306	positive regulation of mast cell degranulation	3/2053	14/18722	0.192560372999126	0.371021913293113	FGR/SYK/SNX4	3
GO:0045006	DNA deamination	3/2053	14/18722	0.192560372999126	0.371021913293113	APOBEC3A/APOBEC3G/APOBEC3C	3
GO:0045059	positive thymic T cell selection	3/2053	14/18722	0.192560372999126	0.371021913293113	PTPRC/CD74/DOCK2	3
GO:0045472	response to ether	3/2053	14/18722	0.192560372999126	0.371021913293113	PTAFR/HNRNPD/CDK4	3
GO:0045820	negative regulation of glycolytic process	3/2053	14/18722	0.192560372999126	0.371021913293113	FBP1/DDIT4/STAT3	3
GO:0046049	UMP metabolic process	3/2053	14/18722	0.192560372999126	0.371021913293113	UPP1/DPYD/UMPS	3
GO:0046341	CDP-diacylglycerol metabolic process	3/2053	14/18722	0.192560372999126	0.371021913293113	AGPAT2/CDS1/CDIPT	3
GO:0047484	regulation of response to osmotic stress	3/2053	14/18722	0.192560372999126	0.371021913293113	ARHGEF2/BAD/EFHD1	3
GO:0050930	induction of positive chemotaxis	3/2053	14/18722	0.192560372999126	0.371021913293113	VEGFA/IL16/CXCL8	3
GO:0051984	positive regulation of chromosome segregation	3/2053	14/18722	0.192560372999126	0.371021913293113	CDC6/CDT1/AURKB	3
GO:0055057	neuroblast division	3/2053	14/18722	0.192560372999126	0.371021913293113	ASPM/ARHGEF2/NUMB	3
GO:0060081	membrane hyperpolarization	3/2053	14/18722	0.192560372999126	0.371021913293113	SOD2/CASP1/PARK7	3
GO:0060088	auditory receptor cell stereocilium organization	3/2053	14/18722	0.192560372999126	0.371021913293113	SOD1/TRIOBP/MYO7A	3
GO:0060841	venous blood vessel development	3/2053	14/18722	0.192560372999126	0.371021913293113	VEGFA/ENG/NOTCH1	3
GO:0072176	nephric duct development	3/2053	14/18722	0.192560372999126	0.371021913293113	AHI1/GATA3/GPC3	3
GO:0072350	tricarboxylic acid metabolic process	3/2053	14/18722	0.192560372999126	0.371021913293113	IDH2/ASS1/IDH1	3
GO:0097531	mast cell migration	3/2053	14/18722	0.192560372999126	0.371021913293113	RAC2/VEGFA/RIN3	3
GO:1901722	regulation of cell proliferation involved in kidney development	3/2053	14/18722	0.192560372999126	0.371021913293113	BMP7/IL6R/GATA3	3
GO:1902036	regulation of hematopoietic stem cell differentiation	3/2053	14/18722	0.192560372999126	0.371021913293113	PRKDC/FOXC1/HSPA9	3
GO:1902916	positive regulation of protein polyubiquitination	3/2053	14/18722	0.192560372999126	0.371021913293113	UBE2D1/SKP2/GABARAP	3
GO:1904923	regulation of autophagy of mitochondrion in response to mitochondrial depolarization	3/2053	14/18722	0.192560372999126	0.371021913293113	HK2/VPS13C/HUWE1	3
GO:2001256	regulation of store-operated calcium entry	3/2053	14/18722	0.192560372999126	0.371021913293113	CD84/HOMER3/HOMER1	3
GO:0032768	regulation of monooxygenase activity	9/2053	59/18722	0.1936701014079	0.373040323739133	EGFR/TNF/IL1B/PTK2B/DHFR/DDAH2/VDR/PARK7/GCH1	9
GO:0035914	skeletal muscle cell differentiation	10/2053	67/18722	0.195001482587147	0.375484241181926	MEF2C/FOS/HIVEP3/NOTCH1/NR4A1/BTG2/UQCC2/KLF5/GPC1/ATF3	10
GO:0050886	endocrine process	12/2053	83/18722	0.195221471353647	0.375787240334259	CYBA/RETN/IL1B/CTSZ/MME/KCNQ1/ENPEP/GJA1/RHOA/GATA3/C1QTNF1/TBX3	12
GO:0072175	epithelial tube formation	18/2053	132/18722	0.195792403410646	0.376765368974945	TGFB1/SPINT1/SPINT2/LRP2/VASP/RPS7/RARA/BMP7/LMO4/SOX4/GATA3/FOLR1/KIF20B/PFN1/LUZP1/STK4/IRX2/COBL	18
GO:0003230	cardiac atrium development	6/2053	36/18722	0.196700068987891	0.377905992291818	ENG/NOTCH1/GJA5/ISL1/NOTCH2/SOX4	6
GO:0010762	regulation of fibroblast migration	6/2053	36/18722	0.196700068987891	0.377905992291818	TGFB1/SLC8A1/ITGB1/ARHGAP4/CORO1C/PTK2	6
GO:0045652	regulation of megakaryocyte differentiation	6/2053	36/18722	0.196700068987891	0.377905992291818	MEF2C/HMGB2/CIB1/SCIN/PITHD1/RCOR1	6
GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	6/2053	36/18722	0.196700068987891	0.377905992291818	CD74/CD44/SKIL/RPS3/TRIAP1/ING2	6
GO:1903539	protein localization to postsynaptic membrane	6/2053	36/18722	0.196700068987891	0.377905992291818	NSG1/DAG1/HRAS/RAP1A/DLG1/CLSTN1	6
GO:0048639	positive regulation of developmental growth	23/2053	174/18722	0.199437025079058	0.383041661483467	CXCR4/MEF2C/FN1/VEGFA/SASH3/PRKDC/CDK1/SERP1/NOTCH1/PPIB/HAMP/TRPV2/ITSN2/NRP1/GOLGA4/TWF2/YAP1/PARP2/EZR/INSR/TGFBR3/BASP1/MAPK14	23
GO:0030198	extracellular matrix organization	38/2053	301/18722	0.199620221036727	0.383270824390516	CTSS/LCP1/TNFRSF1B/TGFB1/TGFBI/CST3/FBLN1/SPINT1/COL14A1/SPINT2/TNF/APP/VWA1/PRDX4/RUNX1/LAMB1/QSOX1/DAG1/ADAMTSL4/ITGB1/DPP4/ENG/NOTCH1/ADAM8/COL4A2/LAMC1/SERPINH1/CTSV/ADAMTS1/FERMT1/ADAMTS6/CCDC80/SULF2/RGCC/COL4A1/ADAMTS19/FOXC1/MMP15	38
GO:0035967	cellular response to topologically incorrect protein	16/2053	116/18722	0.200050360642244	0.383728313252387	HSPD1/SERP1/HSPA5/CCND1/HSPA8/HSPA6/SDF2L1/HSPA14/HSPA1A/PPP1R15A/ATF3/VCP/HSPA9/TM7SF3/DNAJB14/DNAJB9	16
GO:0051283	negative regulation of sequestering of calcium ion	16/2053	116/18722	0.200050360642244	0.383728313252387	PTPRC/CORO1A/CCL3/CYBA/LYN/SLC8A1/CXCL10/PTPN6/PTK2B/CAMK2D/TRPM2/CALM2/MCOLN3/DMD/FKBP1A/UBASH3B	16
GO:0098732	macromolecule deacylation	16/2053	116/18722	0.200050360642244	0.383728313252387	FLNA/LRRK2/VEGFA/BCL6/NOTUM/MORF4L2/PPT1/CAMK2D/JDP2/HDAC2/BEX4/PHB/TBL1X/ING2/RCOR1/NCAPG2	16
GO:0016241	regulation of macroautophagy	19/2053	141/18722	0.202166778383501	0.387664004570473	LRRK2/HMOX1/QSOX1/SLC25A5/BNIP3L/ATP6V1C2/RHEB/SLC25A4/RALB/CAPNS1/VDAC1/VPS13C/SCOC/ATP6V1B1/BNIP3/ATP6V1B2/CAPN1/ATP6V0E1/GAPDH	19
GO:0061013	regulation of mRNA catabolic process	22/2053	166/18722	0.202289888414582	0.38771571317808	VIM/SLC11A1/ZFP36/ZFP36L2/FUS/CARHSP1/PABPC1/ZFP36L1/NPM1/HNRNPR/SERBP1/BTG2/EXOSC8/HNRNPD/MYD88/KHSRP/HNRNPA0/APEX1/AGO2/E2F1/YBX1/MAPK14	22
GO:0007528	neuromuscular junction development	7/2053	44/18722	0.202452221564487	0.38771571317808	LRRK2/APP/ANK3/COL4A1/AFG3L2/PTN/PPFIBP1	7
GO:0050999	regulation of nitric-oxide synthase activity	7/2053	44/18722	0.202452221564487	0.38771571317808	EGFR/TNF/IL1B/PTK2B/DHFR/DDAH2/GCH1	7
GO:1903214	regulation of protein targeting to mitochondrion	7/2053	44/18722	0.202452221564487	0.38771571317808	RAC2/LRRK2/LMAN1/BNIP3L/PDCD5/SAE1/HUWE1	7
GO:0009062	fatty acid catabolic process	14/2053	100/18722	0.203795571051061	0.390163824603179	SLC27A2/ECI1/ECHS1/ACADVL/ECHDC2/ETFB/NUDT8/HADH/ETFA/ACAT2/ABHD2/ECI2/SLC25A17/ECH1	14
GO:0006997	nucleus organization	18/2053	133/18722	0.204736814579198	0.391590974649406	HMGB2/CDK1/VRK1/PRKCB/SERBP1/CHEK1/RPS19/SF1/TPR/TMEM170A/SRPK1/UBXN2A/RNF8/CHMP4C/LMNA/NUP54/PITPNB/SMARCA5	18
GO:0046328	regulation of JNK cascade	18/2053	133/18722	0.204736814579198	0.391590974649406	NCF1/PYCARD/HMGB1/EGFR/TNF/TLR4/IL1B/GSTP1/APP/GADD45B/PTK2B/HRAS/MARVELD3/SIRPA/SDCBP/MYD88/RASSF2/IGF1R	18
GO:0046887	positive regulation of hormone secretion	18/2053	133/18722	0.204736814579198	0.391590974649406	HLA-DRB1/EGFR/SPP1/JAK2/RETN/GLUL/MPC2/SERP1/GJA1/TRPM2/ISL1/SOX4/SNX4/ACSL4/PHPT1/BAD/C1QTNF1/TM7SF3	18
GO:0018393	internal peptidyl-lysine acetylation	21/2053	158/18722	0.205166054902965	0.392286911860354	SPI1/IL1B/MORF4L2/BRCA1/SET/CHEK1/HAT1/ISL1/BRD7/GATA3/BRCA2/POLE3/EID1/USP22/PARK7/ZNF451/PHF20/YEATS4/ACTL6A/RPS6KA5/MBD3	21
GO:0043062	extracellular structure organization	38/2053	302/18722	0.205529630451246	0.392776149988069	CTSS/LCP1/TNFRSF1B/TGFB1/TGFBI/CST3/FBLN1/SPINT1/COL14A1/SPINT2/TNF/APP/VWA1/PRDX4/RUNX1/LAMB1/QSOX1/DAG1/ADAMTSL4/ITGB1/DPP4/ENG/NOTCH1/ADAM8/COL4A2/LAMC1/SERPINH1/CTSV/ADAMTS1/FERMT1/ADAMTS6/CCDC80/SULF2/RGCC/COL4A1/ADAMTS19/FOXC1/MMP15	38
GO:0021545	cranial nerve development	8/2053	52/18722	0.205683777210419	0.392776149988069	MAFB/NRP2/TFAP2A/NRP1/ISL1/TCIRG1/GLI3/SLC1A3	8
GO:0035196	production of miRNAs involved in gene silencing by miRNA	8/2053	52/18722	0.205683777210419	0.392776149988069	TGFB1/EGFR/TNF/LIN28B/STAT3/NCOR2/HNRNPA2B1/AGO2	8
GO:0043090	amino acid import	8/2053	52/18722	0.205683777210419	0.392776149988069	ITGB1/SLC6A6/SLC1A5/SFXN3/SFXN1/RGS2/SLC3A2/SLC1A3	8
GO:0003209	cardiac atrium morphogenesis	5/2053	29/18722	0.206806729495504	0.393418001576736	ENG/NOTCH1/ISL1/NOTCH2/SOX4	5
GO:0006656	phosphatidylcholine biosynthetic process	5/2053	29/18722	0.206806729495504	0.393418001576736	CHPT1/FABP5/CDS1/SLC44A1/SLC44A2	5
GO:0007143	female meiotic nuclear division	5/2053	29/18722	0.206806729495504	0.393418001576736	TOP2A/UBB/RAD51C/FBXO5/TTK	5
GO:0009218	pyrimidine ribonucleotide metabolic process	5/2053	29/18722	0.206806729495504	0.393418001576736	UPP1/DPYD/UMPS/NME4/NME1	5
GO:0010592	positive regulation of lamellipodium assembly	5/2053	29/18722	0.206806729495504	0.393418001576736	RAC2/ACTR2/TWF2/ACTR3/WASF2	5
GO:0019359	nicotinamide nucleotide biosynthetic process	5/2053	29/18722	0.206806729495504	0.393418001576736	NAMPT/KYNU/QPRT/PARP9/IDH2	5
GO:0019363	pyridine nucleotide biosynthetic process	5/2053	29/18722	0.206806729495504	0.393418001576736	NAMPT/KYNU/QPRT/PARP9/IDH2	5
GO:0021591	ventricular system development	5/2053	29/18722	0.206806729495504	0.393418001576736	C12orf57/CENPF/SEMA6D/CDK6/NUMB	5
GO:0021602	cranial nerve morphogenesis	5/2053	29/18722	0.206806729495504	0.393418001576736	MAFB/NRP2/TFAP2A/NRP1/GLI3	5
GO:0034067	protein localization to Golgi apparatus	5/2053	29/18722	0.206806729495504	0.393418001576736	SORL1/GBP5/OBSL1/VPS13C/ARL1	5
GO:0034311	diol metabolic process	5/2053	29/18722	0.206806729495504	0.393418001576736	DHFR/SPHK1/PLPP3/GCH1/QDPR	5
GO:0071549	cellular response to dexamethasone stimulus	5/2053	29/18722	0.206806729495504	0.393418001576736	EGFR/SERPINF1/ICAM1/DDIT4/ASS1	5
GO:0033866	nucleoside bisphosphate biosynthetic process	9/2053	60/18722	0.207279369675938	0.393568423435326	SLC26A2/MPC2/ACSS1/TECR/PDK4/PPT1/SLC25A1/ACSL4/PDHA1	9
GO:0034030	ribonucleoside bisphosphate biosynthetic process	9/2053	60/18722	0.207279369675938	0.393568423435326	SLC26A2/MPC2/ACSS1/TECR/PDK4/PPT1/SLC25A1/ACSL4/PDHA1	9
GO:0034033	purine nucleoside bisphosphate biosynthetic process	9/2053	60/18722	0.207279369675938	0.393568423435326	SLC26A2/MPC2/ACSS1/TECR/PDK4/PPT1/SLC25A1/ACSL4/PDHA1	9
GO:0055008	cardiac muscle tissue morphogenesis	9/2053	60/18722	0.207279369675938	0.393568423435326	TGFB1/LRP2/DSP/ENG/NOTCH1/ISL1/FKBP1A/FOXC1/TGFBR3	9
GO:0060038	cardiac muscle cell proliferation	9/2053	60/18722	0.207279369675938	0.393568423435326	MEF2C/RUNX1/CDK1/NOTCH1/GJA1/YAP1/FOXC1/TGFBR3/MAPK14	9
GO:0061951	establishment of protein localization to plasma membrane	9/2053	60/18722	0.207279369675938	0.393568423435326	VAMP5/KRT18/NSG1/CSK/GOLGA4/ANK3/SPTBN1/GOPC/RILPL2	9
GO:0014855	striated muscle cell proliferation	11/2053	76/18722	0.207471614662096	0.393808822515843	MEF2C/JAK2/RUNX1/CDK1/NOTCH1/GJA1/STAT3/YAP1/FOXC1/TGFBR3/MAPK14	11
GO:0043543	protein acylation	31/2053	243/18722	0.210073474014931	0.398621392817706	SPI1/IL1B/GLUL/CAMK1/ZDHHC12/MORF4L2/BRCA1/HINT2/SET/CHEK1/HAT1/SPHK1/ISL1/SOX4/HDAC2/BRD7/GATA3/DSCC1/BRCA2/ESCO2/POLE3/EID1/USP22/PARK7/NMT1/ZNF451/PHF20/YEATS4/ACTL6A/RPS6KA5/MBD3	31
GO:0034728	nucleosome organization	22/2053	167/18722	0.210374700491557	0.399066772984301	NASP/HMGB2/DNAJC9/CENPW/SUPT16H/NPM1/ASF1B/SET/NAP1L1/RBBP4/MCM2/HAT1/ITGB3BP/HMGA1/SMARCC1/CHAF1A/POLE3/MIS18A/RNF8/NAP1L4/ACTR6/SMARCA5	22
GO:0060070	canonical Wnt signaling pathway	38/2053	303/18722	0.211527427381663	0.401126600597338	ZEB2/TGFB1/KLF4/EGFR/LRRK2/NR4A2/WLS/PFDN5/NOTCH1/HHEX/RPS12/NOTUM/LGR5/ASPM/KANK1/TPBG/FERMT1/SULF2/ISL1/SIAH2/SOX4/GATA3/FOLR1/LRP5/PLPP3/LGR4/YAP1/TLE1/TBL1X/GLI3/STK4/VCP/MDK/CTNND1/ZNRF3/PTPRU/MAPK14/GPC3	38
GO:0006476	protein deacetylation	14/2053	101/18722	0.2143717213204	0.406065658839121	FLNA/LRRK2/VEGFA/BCL6/MORF4L2/CAMK2D/JDP2/HDAC2/BEX4/PHB/TBL1X/ING2/RCOR1/NCAPG2	14
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	6/2053	37/18722	0.214605700696476	0.406065658839121	RPS21/RPS16/RPS14/RPS19/RPS8/BMS1	6
GO:0051294	establishment of spindle orientation	6/2053	37/18722	0.214605700696476	0.406065658839121	ITGB1/MAD2L1/GJA1/NDC80/GPSM2/DYNLT1	6
GO:0060306	regulation of membrane repolarization	6/2053	37/18722	0.214605700696476	0.406065658839121	FLNA/KCNQ1/KCNE3/GJA5/YWHAE/AKAP9	6
GO:0062237	protein localization to postsynapse	6/2053	37/18722	0.214605700696476	0.406065658839121	NSG1/DAG1/HRAS/RAP1A/DLG1/CLSTN1	6
GO:1900016	negative regulation of cytokine production involved in inflammatory response	6/2053	37/18722	0.214605700696476	0.406065658839121	PYCARD/LILRB4/TREM2/EZH2/SIRPA/CHID1	6
GO:1902745	positive regulation of lamellipodium organization	6/2053	37/18722	0.214605700696476	0.406065658839121	RAC2/ACTR2/TWF2/ACTR3/WASF2/CORO1C	6
GO:0048880	sensory system development	47/2053	381/18722	0.214711332961632	0.40613745200813	VIM/EFEMP1/HMGB1/SKIL/KLF4/FBN2/VEGFA/ITGAM/FBN1/SERPINF1/RRM1/C3/PFDN5/SCO2/TENM3/RARA/C12orf57/BMP7/ATP2B1/C1QA/FLT1/MFAP5/FAT1/TFAP2A/NRP1/ISL1/NOTCH2/STAT3/HDAC2/AHI1/GATA3/CDK4/PBX1/LRP5/COL4A1/HMGN1/OBSL1/IMPDH2/DLG1/TCIRG1/GLI3/FOXC1/FJX1/PTN/ACTL6A/MYO7A/MEIS2	47
GO:0006662	glycerol ether metabolic process	4/2053	22/18722	0.216148315268313	0.406293825692317	LPCAT2/PLA2G7/CHPT1/TXN	4
GO:0006907	pinocytosis	4/2053	22/18722	0.216148315268313	0.406293825692317	PYCARD/DOCK2/PPT1/MAPKAPK3	4
GO:0009220	pyrimidine ribonucleotide biosynthetic process	4/2053	22/18722	0.216148315268313	0.406293825692317	UPP1/UMPS/NME4/NME1	4
GO:0010310	regulation of hydrogen peroxide metabolic process	4/2053	22/18722	0.216148315268313	0.406293825692317	RAC2/SOD2/PRDX2/STAT3	4
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	4/2053	22/18722	0.216148315268313	0.406293825692317	SLC8A1/CAMK2D/CALM2/DMD	4
GO:0021854	hypothalamus development	4/2053	22/18722	0.216148315268313	0.406293825692317	NRP2/UBB/UQCRQ/NRP1	4
GO:0032816	positive regulation of natural killer cell activation	4/2053	22/18722	0.216148315268313	0.406293825692317	TYROBP/HLA-F/HLA-E/IL18	4
GO:0034755	iron ion transmembrane transport	4/2053	22/18722	0.216148315268313	0.406293825692317	SLC11A1/SLC40A1/SLC25A37/HAMP	4
GO:0035357	peroxisome proliferator activated receptor signaling pathway	4/2053	22/18722	0.216148315268313	0.406293825692317	FABP5/ASXL1/ACTN4/PPARG	4
GO:0035584	calcium-mediated signaling using intracellular calcium source	4/2053	22/18722	0.216148315268313	0.406293825692317	PTPRC/TRPM2/FIS1/DEFB1	4
GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	4/2053	22/18722	0.216148315268313	0.406293825692317	HMGB1/RUNX1/BCL6/RUNX3	4
GO:0044346	fibroblast apoptotic process	4/2053	22/18722	0.216148315268313	0.406293825692317	BTG1/STK17A/STK17B/XRCC2	4
GO:0055093	response to hyperoxia	4/2053	22/18722	0.216148315268313	0.406293825692317	HDAC2/CDK4/CDKN1A/BNIP3	4
GO:0060444	branching involved in mammary gland duct morphogenesis	4/2053	22/18722	0.216148315268313	0.406293825692317	PHB2/VDR/LRP5/TBX3	4
GO:0071467	cellular response to pH	4/2053	22/18722	0.216148315268313	0.406293825692317	HVCN1/CHP1/GNA11/SLC9A1	4
GO:0099563	modification of synaptic structure	4/2053	22/18722	0.216148315268313	0.406293825692317	MYH10/STAU1/RHOA/PFN1	4
GO:0140467	integrated stress response signaling	4/2053	22/18722	0.216148315268313	0.406293825692317	HSPA5/EIF2AK4/EIF2AK1/PPP1R15A	4
GO:1900120	regulation of receptor binding	4/2053	22/18722	0.216148315268313	0.406293825692317	B2M/PHLDA2/NRP1/PTPRF	4
GO:1900543	negative regulation of purine nucleotide metabolic process	4/2053	22/18722	0.216148315268313	0.406293825692317	FBP1/PARP1/DDIT4/STAT3	4
GO:2000114	regulation of establishment of cell polarity	4/2053	22/18722	0.216148315268313	0.406293825692317	PTK2B/KANK1/GATA3/KIF20B	4
GO:0001935	endothelial cell proliferation	25/2053	193/18722	0.216300899757254	0.406453303646578	CYBA/MEF2C/HMGB1/VEGFA/ALOX5/TNF/HMGB2/ITGA4/STAT1/HMOX1/NRP2/VASH1/NR2F2/TNFSF12/NR4A1/STAT5A/FLT1/GJA1/NRP1/STAT3/MYDGF/RGCC/DLG1/MDK/PPARG	25
GO:0048592	eye morphogenesis	20/2053	151/18722	0.216714320348104	0.406975249480008	EFEMP1/FBN2/VEGFA/FBN1/TENM3/C12orf57/BMP7/MFAP5/FAT1/TFAP2A/NOTCH2/STAT3/AHI1/LRP5/HMGN1/OBSL1/GLI3/FJX1/PTN/MYO7A	20
GO:1904064	positive regulation of cation transmembrane transport	20/2053	151/18722	0.216714320348104	0.406975249480008	CTSS/TMSB4X/FLNA/CCR2/CXCL10/GLRX/IFNGR2/TREM2/KCNQ1/VMP1/KCNMB1/KCNE3/CHP1/CALM2/ANK3/KCNN4/SLC9A1/DMD/AKAP9/ACTN4	20
GO:0045229	external encapsulating structure organization	38/2053	304/18722	0.21761208943513	0.408533334358818	CTSS/LCP1/TNFRSF1B/TGFB1/TGFBI/CST3/FBLN1/SPINT1/COL14A1/SPINT2/TNF/APP/VWA1/PRDX4/RUNX1/LAMB1/QSOX1/DAG1/ADAMTSL4/ITGB1/DPP4/ENG/NOTCH1/ADAM8/COL4A2/LAMC1/SERPINH1/CTSV/ADAMTS1/FERMT1/ADAMTS6/CCDC80/SULF2/RGCC/COL4A1/ADAMTS19/FOXC1/MMP15	38
GO:0010507	negative regulation of autophagy	12/2053	85/18722	0.218298671134695	0.409565987119502	TSPO/IL10RA/LRRK2/HMOX1/NAMPT/MET/QSOX1/TREM2/MCL1/STAT3/SNRNP70/EIF4G1	12
GO:0055013	cardiac muscle cell development	12/2053	85/18722	0.218298671134695	0.409565987119502	SLC8A1/VEGFA/MEF2A/CDK1/HAMP/ISL1/PARP2/OBSL1/RGS2/FHL2/LMNA/TBX3	12
GO:0099173	postsynapse organization	22/2053	168/18722	0.218610158793942	0.410022179669788	SRGN/LILRB2/ACTB/ABI3/LRRK2/DOCK10/NRP2/TREM2/ZDHHC12/HSPA8/NRP1/ACTR2/EFNA1/WASF2/DLG1/IGF1R/CHRNB1/INSR/PTN/CFL1/NDRG1/HOMER1	22
GO:0042551	neuron maturation	7/2053	45/18722	0.218759722929507	0.410174480492826	LRRK2/NR4A2/APP/C3/C1QA/CNTNAP2/RAC3	7
GO:0051282	regulation of sequestering of calcium ion	16/2053	118/18722	0.219628491307747	0.410666327757478	PTPRC/CORO1A/CCL3/CYBA/LYN/SLC8A1/CXCL10/PTPN6/PTK2B/CAMK2D/TRPM2/CALM2/MCOLN3/DMD/FKBP1A/UBASH3B	16
GO:0048644	muscle organ morphogenesis	11/2053	77/18722	0.219811958954367	0.410666327757478	TGFB1/LRP2/DSP/SERP1/ENG/NOTCH1/ISL1/ARID5B/FKBP1A/FOXC1/TGFBR3	11
GO:0062013	positive regulation of small molecule metabolic process	19/2053	143/18722	0.21993580802763	0.410666327757478	TMSB4X/CD74/HMGB1/TNF/IL1B/APP/PTAFR/TREM2/COMT/P2RX7/PMAIP1/DDB1/STAT3/MID1IP1/PARK7/INSR/VCP/LDLRAP1/PPARG	19
GO:0006368	transcription elongation from RNA polymerase II promoter	10/2053	69/18722	0.220863809360985	0.410666327757478	CDCA4/SUPT16H/RTF1/EZH2/CHEK1/BRD4/POLR2I/ELL2/RNF8/NELFCD	10
GO:0015807	L-amino acid transport	10/2053	69/18722	0.220863809360985	0.410666327757478	SLC11A1/SLC7A7/SLC38A1/ITGB1/SLC1A5/SFXN1/SLC7A6/SLC38A9/SLC3A2/SLC1A3	10
GO:0050805	negative regulation of synaptic transmission	10/2053	69/18722	0.220863809360985	0.410666327757478	LILRB2/LRRK2/IL1B/PTK2B/PNKD/GNAI2/SLC6A4/RAP1A/GNAI1/PLK2	10
GO:0043954	cellular component maintenance	9/2053	61/18722	0.221262462844177	0.410666327757478	CSF1R/TREM2/TJP1/FERMT2/CHCHD10/DLG1/IGF1R/INSR/HOMER1	9
GO:0006475	internal protein amino acid acetylation	21/2053	160/18722	0.222041456543822	0.410666327757478	SPI1/IL1B/MORF4L2/BRCA1/SET/CHEK1/HAT1/ISL1/BRD7/GATA3/BRCA2/POLE3/EID1/USP22/PARK7/ZNF451/PHF20/YEATS4/ACTL6A/RPS6KA5/MBD3	21
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3/2053	15/18722	0.222340096315654	0.410666327757478	RPL35/RPL7/DDX18	3
GO:0010273	detoxification of copper ion	3/2053	15/18722	0.222340096315654	0.410666327757478	MT1X/MT2A/PARK7	3
GO:0010713	negative regulation of collagen metabolic process	3/2053	15/18722	0.222340096315654	0.410666327757478	CST3/CIITA/RAP1A	3
GO:0010889	regulation of sequestering of triglyceride	3/2053	15/18722	0.222340096315654	0.410666327757478	TREM2/PLIN2/PPARG	3
GO:0018410	C-terminal protein amino acid modification	3/2053	15/18722	0.222340096315654	0.410666327757478	ICMT/LCMT1/WIPI2	3
GO:0019511	peptidyl-proline hydroxylation	3/2053	15/18722	0.222340096315654	0.410666327757478	P4HB/PRDX4/P3H1	3
GO:0021542	dentate gyrus development	3/2053	15/18722	0.222340096315654	0.410666327757478	BTG2/CDK6/MDK	3
GO:0031958	corticosteroid receptor signaling pathway	3/2053	15/18722	0.222340096315654	0.410666327757478	JAK2/CALR/PHB	3
GO:0032354	response to follicle-stimulating hormone	3/2053	15/18722	0.222340096315654	0.410666327757478	NOTCH1/GCLM/TGFBR3	3
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	3/2053	15/18722	0.222340096315654	0.410666327757478	BRCA1/PHB2/ISL1	3
GO:0042074	cell migration involved in gastrulation	3/2053	15/18722	0.222340096315654	0.410666327757478	AMOT/LRP5/GPC3	3
GO:0042159	lipoprotein catabolic process	3/2053	15/18722	0.222340096315654	0.410666327757478	CTSD/NOTUM/PPT1	3
GO:0042182	ketone catabolic process	3/2053	15/18722	0.222340096315654	0.410666327757478	KYNU/PNKD/PARK7	3
GO:0042559	pteridine-containing compound biosynthetic process	3/2053	15/18722	0.222340096315654	0.410666327757478	DHFR/GCH1/QDPR	3
GO:0042994	cytoplasmic sequestering of transcription factor	3/2053	15/18722	0.222340096315654	0.410666327757478	TMSB4X/NFKBIA/NFKBIE	3
GO:0044793	negative regulation by host of viral process	3/2053	15/18722	0.222340096315654	0.410666327757478	NUCKS1/PSMC3/EIF2AK4	3
GO:0045217	cell-cell junction maintenance	3/2053	15/18722	0.222340096315654	0.410666327757478	CSF1R/TJP1/FERMT2	3
GO:0045986	negative regulation of smooth muscle contraction	3/2053	15/18722	0.222340096315654	0.410666327757478	DOCK4/SOD1/RGS2	3
GO:0048308	organelle inheritance	3/2053	15/18722	0.222340096315654	0.410666327757478	PLK3/CDK1/VRK1	3
GO:0048313	Golgi inheritance	3/2053	15/18722	0.222340096315654	0.410666327757478	PLK3/CDK1/VRK1	3
GO:0050746	regulation of lipoprotein metabolic process	3/2053	15/18722	0.222340096315654	0.410666327757478	DBI/ITGAV/SVIP	3
GO:0051127	positive regulation of actin nucleation	3/2053	15/18722	0.222340096315654	0.410666327757478	WAS/SCIN/WASF2	3
GO:0051290	protein heterotetramerization	3/2053	15/18722	0.222340096315654	0.410666327757478	RRM1/RRM2/KRT10	3
GO:0051299	centrosome separation	3/2053	15/18722	0.222340096315654	0.410666327757478	RANBP1/CHEK1/KIF11	3
GO:0051608	histamine transport	3/2053	15/18722	0.222340096315654	0.410666327757478	LYN/BTK/SNX4	3
GO:0060413	atrial septum morphogenesis	3/2053	15/18722	0.222340096315654	0.410666327757478	ISL1/NOTCH2/SOX4	3
GO:0070207	protein homotrimerization	3/2053	15/18722	0.222340096315654	0.410666327757478	ALOX5AP/SLC1A5/SIGMAR1	3
GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	3/2053	15/18722	0.222340096315654	0.410666327757478	HOMER3/CHP1/FHL2	3
GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	3/2053	15/18722	0.222340096315654	0.410666327757478	TNF/CIB1/SLC9A1	3
GO:0072044	collecting duct development	3/2053	15/18722	0.222340096315654	0.410666327757478	NOTCH1/AKR1B1/DLG5	3
GO:0072075	metanephric mesenchyme development	3/2053	15/18722	0.222340096315654	0.410666327757478	STAT1/BMP7/BASP1	3
GO:0106057	negative regulation of calcineurin-mediated signaling	3/2053	15/18722	0.222340096315654	0.410666327757478	HOMER3/CHP1/FHL2	3
GO:0106058	positive regulation of calcineurin-mediated signaling	3/2053	15/18722	0.222340096315654	0.410666327757478	TNF/CIB1/SLC9A1	3
GO:1900102	negative regulation of endoplasmic reticulum unfolded protein response	3/2053	15/18722	0.222340096315654	0.410666327757478	HSPA5/PPP1R15A/DNAJB9	3
GO:1901660	calcium ion export	3/2053	15/18722	0.222340096315654	0.410666327757478	ATP2B1/CALM2/YWHAE	3
GO:1902018	negative regulation of cilium assembly	3/2053	15/18722	0.222340096315654	0.410666327757478	YAP1/CCP110/ODF2L	3
GO:1990169	stress response to copper ion	3/2053	15/18722	0.222340096315654	0.410666327757478	MT1X/MT2A/PARK7	3
GO:1990822	basic amino acid transmembrane transport	3/2053	15/18722	0.222340096315654	0.410666327757478	SLC7A7/SLC7A6/SLC38A9	3
GO:2001028	positive regulation of endothelial cell chemotaxis	3/2053	15/18722	0.222340096315654	0.410666327757478	TMSB4X/VEGFA/MET	3
GO:2001279	regulation of unsaturated fatty acid biosynthetic process	3/2053	15/18722	0.222340096315654	0.410666327757478	CD74/IL1B/FABP5	3
GO:0003014	renal system process	15/2053	110/18722	0.222444260868634	0.410666327757478	CYBA/SGK1/CLDN4/KCNQ1/EMP2/COMT/GJA1/GNAI2/AKR1B1/GJA5/SULF2/RHOA/MAGED2/ATP6V1B1/PKN1	15
GO:0009063	cellular amino acid catabolic process	15/2053	110/18722	0.222444260868634	0.410666327757478	SDS/GCSH/KYNU/GLUL/IL4I1/ECHS1/DDAH2/GLDC/SDSL/CDO1/OAT/QDPR/SHMT1/PPAT/ENOSF1	15
GO:0090501	RNA phosphodiester bond hydrolysis	20/2053	152/18722	0.225530638951738	0.416236183854331	SAMHD1/RPS21/ISG20/RNASE6/FEN1/RNASET2/POP7/EXOSC8/RNASEH2A/NHP2/POLR3K/TSEN34/POLR2I/SND1/APEX1/AGO2/EXO1/TOE1/LACTB2/BMS1	20
GO:0006937	regulation of muscle contraction	22/2053	169/18722	0.226991838680008	0.418635258463376	SLC8A1/DSP/PTAFR/DOCK4/SOD1/C12orf57/ATP2B1/KCNQ1/TNNI2/NR4A1/DSG2/CAMK2D/GJA5/SPHK1/DSC2/RHOA/CALM2/RGS2/SLC9A1/DLG1/DMD/AKAP9	22
GO:0019674	NAD metabolic process	5/2053	30/18722	0.227458490431767	0.418635258463376	QPRT/HK3/HK2/LDHA/MDH1	5
GO:0032480	negative regulation of type I interferon production	5/2053	30/18722	0.227458490431767	0.418635258463376	PYCARD/HAVCR2/LILRB1/SIRPA/REL	5
GO:0048147	negative regulation of fibroblast proliferation	5/2053	30/18722	0.227458490431767	0.418635258463376	IFI30/FTH1/CD300A/GSTP1/PAWR	5
GO:0051125	regulation of actin nucleation	5/2053	30/18722	0.227458490431767	0.418635258463376	GMFG/CORO1A/WAS/SCIN/WASF2	5
GO:0060603	mammary gland duct morphogenesis	5/2053	30/18722	0.227458490431767	0.418635258463376	CSF1R/PHB2/VDR/LRP5/TBX3	5
GO:0070498	interleukin-1-mediated signaling pathway	5/2053	30/18722	0.227458490431767	0.418635258463376	IRAK3/IL1B/IL1RN/MYD88/RPS6KA5	5
GO:0090151	establishment of protein localization to mitochondrial membrane	5/2053	30/18722	0.227458490431767	0.418635258463376	HSP90AA1/TIMM13/PDCD5/NMT1/NDUFA13	5
GO:2000648	positive regulation of stem cell proliferation	5/2053	30/18722	0.227458490431767	0.418635258463376	PTPRC/CCNE1/GJA1/FERMT2/TBX3	5
GO:0019080	viral gene expression	13/2053	94/18722	0.227799431762406	0.419134189075264	CCL3/ZFP36/CCL4/IFITM3/NUCKS1/PARP9/PSMC3/FUT8/EIF2AK4/JUN/DENR/EIF3A/EIF3L	13
GO:0150063	visual system development	46/2053	375/18722	0.229413085193305	0.421973792507612	VIM/EFEMP1/HMGB1/SKIL/KLF4/FBN2/VEGFA/ITGAM/FBN1/SERPINF1/RRM1/C3/PFDN5/SCO2/TENM3/RARA/C12orf57/BMP7/ATP2B1/C1QA/FLT1/MFAP5/FAT1/TFAP2A/NRP1/NOTCH2/STAT3/HDAC2/AHI1/GATA3/CDK4/PBX1/LRP5/COL4A1/HMGN1/OBSL1/IMPDH2/DLG1/TCIRG1/GLI3/FOXC1/FJX1/PTN/ACTL6A/MYO7A/MEIS2	46
GO:0015908	fatty acid transport	12/2053	86/18722	0.23024484522395	0.423373910923598	IL1B/CD36/SLC2A1/SLC27A2/SYK/PLIN2/FABP5/ACSL4/FIS1/PTGES/SLC25A17/PPARG	12
GO:0042692	muscle cell differentiation	47/2053	384/18722	0.231304808598081	0.425192662864119	CD53/TGFB1/CD9/SLC8A1/MEF2C/GPX1/PLEKHO1/SOD2/VEGFA/CSRP2/ARRB2/CXCL10/MEF2A/CAMK1/DNMT1/RARA/CDK1/ITGB1/ERVW-1/ENG/NOTCH1/CALR/HAMP/MORF4L2/EZH2/KRT8/ISL1/CACYBP/PARP2/KLF5/AFG3L2/OBSL1/FOXO4/RGS2/SLC9A1/FHL2/DMD/CHRNB1/ID2/KDM6B/BHLHE41/LMNA/TBX3/YBX1/HOMER1/MAPK14/ACTN4	47
GO:0043624	cellular protein complex disassembly	18/2053	136/18722	0.232673387279248	0.427336736201078	PLEK/CAPG/STMN1/DSTN/HSPA8/RDX/CIB1/TPX2/CKAP2/TWF2/SCIN/MID1IP1/SPTBN1/EPS8/ARHGEF2/LIMA1/TRIOBP/CFL1	18
GO:0090288	negative regulation of cellular response to growth factor stimulus	15/2053	111/18722	0.232983023429374	0.427336736201078	SORL1/SKIL/FBN1/LRP2/NOTCH1/HHEX/CRIM1/SEMA6A/SULF2/GATA3/EPN2/UBE2D1/GPC1/CTDSPL2/PPARG	15
GO:0006882	cellular zinc ion homeostasis	6/2053	38/18722	0.233040966808321	0.427336736201078	S100A8/MT1X/S100A9/SLC39A10/MT2A/SLC39A7	6
GO:0051930	regulation of sensory perception of pain	6/2053	38/18722	0.233040966808321	0.427336736201078	CCL3/PTAFR/COMT/FABP5/SLC9A1/MGLL	6
GO:0072524	pyridine-containing compound metabolic process	6/2053	38/18722	0.233040966808321	0.427336736201078	NAMPT/KYNU/QPRT/PARP9/IDH2/PNP	6
GO:0098926	postsynaptic signal transduction	6/2053	38/18722	0.233040966808321	0.427336736201078	JAK2/RGS10/GNA15/GNAI2/STAT3/GNA11	6
GO:0099622	cardiac muscle cell membrane repolarization	6/2053	38/18722	0.233040966808321	0.427336736201078	FLNA/KCNQ1/KCNE3/GJA5/YWHAE/AKAP9	6
GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	6/2053	38/18722	0.233040966808321	0.427336736201078	SLC25A5/BNIP3L/CHCHD10/HSPA1A/NMT1/BNIP3	6
GO:0010828	positive regulation of glucose transmembrane transport	7/2053	46/18722	0.235514805602251	0.431477506446871	C3/MEF2A/RAP1A/RHOQ/INSR/MAPK14/GPC3	7
GO:0043616	keratinocyte proliferation	7/2053	46/18722	0.235514805602251	0.431477506446871	ZFP36/ZFP36L1/FERMT1/NOTCH2/VDR/YAP1/MDK	7
GO:0045851	pH reduction	7/2053	46/18722	0.235514805602251	0.431477506446871	SLC11A1/GRN/PPT1/DMXL2/ATP6V1B1/TCIRG1/ATP6V0E1	7
GO:0070265	necrotic cell death	9/2053	62/18722	0.235593410961959	0.431489763666591	TSPO/CASP1/TNF/BIRC3/SLC6A6/SLC25A4/HEBP2/ARHGEF2/BNIP3	9
GO:0031050	dsRNA processing	8/2053	54/18722	0.236138797638023	0.432092950847252	TGFB1/EGFR/TNF/LIN28B/STAT3/NCOR2/HNRNPA2B1/AGO2	8
GO:0070918	production of small RNA involved in gene silencing by RNA	8/2053	54/18722	0.236138797638023	0.432092950847252	TGFB1/EGFR/TNF/LIN28B/STAT3/NCOR2/HNRNPA2B1/AGO2	8
GO:0072348	sulfur compound transport	8/2053	54/18722	0.236138797638023	0.432092950847252	SLC26A2/LRRC8C/GJA1/SLC6A6/SLC13A4/MGST1/SLC13A3/SLC19A3	8
GO:0090277	positive regulation of peptide hormone secretion	14/2053	103/18722	0.236212761738193	0.432096515374742	HLA-DRB1/EGFR/JAK2/GLUL/MPC2/SERP1/GJA1/TRPM2/ISL1/SOX4/ACSL4/PHPT1/BAD/TM7SF3	14
GO:1901379	regulation of potassium ion transmembrane transport	13/2053	95/18722	0.239380198513817	0.437716335027577	FLNA/ITGB1/KCNAB2/TREM2/KCNQ1/KCNMB1/KCNE3/ANK3/CD63/KCNN4/YWHAE/DLG1/AKAP9	13
GO:0046942	carboxylic acid transport	34/2053	273/18722	0.239430835260085	0.437716335027577	SLC11A1/SLC7A7/SLC16A3/PSAP/LRP2/AQP9/IL1B/CD36/SLC38A1/SLC26A2/SYK/MPC2/ITGB1/LRRC8C/GJA1/SLC6A6/SLC25A1/SLC1A5/SLC16A12/SFXN3/SLC16A1/FOLR1/SLC19A1/SFXN1/RGS2/SLC13A3/PTGES/SLC7A6/SLC38A9/MPC1/SLC38A6/SLC3A2/SLC1A3/SLC10A3	34
GO:0045664	regulation of neuron differentiation	25/2053	196/18722	0.23995184135069	0.438097489863065	B2M/MEF2C/LRRK2/APP/RARA/BMP7/TIMP2/NREP/NOTCH1/BCL6/CALR/ASPM/SLC6A4/ISL1/RHOA/PBX1/ESRP1/EIF2AK4/ECT2/ARHGEF2/GLI3/ID2/PRPF19/EIF4G1/RAC3	25
GO:0048675	axon extension	16/2053	120/18722	0.240005261817263	0.438097489863065	FN1/VEGFA/NRP2/HSP90AA1/HSP90AB1/ITGB1/ALCAM/SEMA4A/ARHGAP4/TRPV2/SEMA6A/NRP1/GOLGA4/TWF2/SEMA6D/VCL	16
GO:0002082	regulation of oxidative phosphorylation	4/2053	23/18722	0.240661554431444	0.438097489863065	UQCC2/RHOA/COX7A2/VCP	4
GO:0003283	atrial septum development	4/2053	23/18722	0.240661554431444	0.438097489863065	GJA5/ISL1/NOTCH2/SOX4	4
GO:0021544	subpallium development	4/2053	23/18722	0.240661554431444	0.438097489863065	LRRK2/CNTNAP2/ZSWIM6/GLI3	4
GO:0021884	forebrain neuron development	4/2053	23/18722	0.240661554431444	0.438097489863065	NRP2/UBB/UQCRQ/NRP1	4
GO:0030325	adrenal gland development	4/2053	23/18722	0.240661554431444	0.438097489863065	TSPO/PBX1/ARID5B/MDK	4
GO:0031280	negative regulation of cyclase activity	4/2053	23/18722	0.240661554431444	0.438097489863065	CCR2/P2RY13/GNAI2/AKAP9	4
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	4/2053	23/18722	0.240661554431444	0.438097489863065	CHPF/CHST15/DSE/B3GAT3	4
GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	4/2053	23/18722	0.240661554431444	0.438097489863065	KCNQ1/KCNE3/GJA5/AKAP9	4
GO:0060353	regulation of cell adhesion molecule production	4/2053	23/18722	0.240661554431444	0.438097489863065	COLEC12/IL1B/NOTCH1/CXCL8	4
GO:0060384	innervation	4/2053	23/18722	0.240661554431444	0.438097489863065	ITGA4/SULF2/NRP1/ISL1	4
GO:0071305	cellular response to vitamin D	4/2053	23/18722	0.240661554431444	0.438097489863065	ATP2B1/VDR/TRIM24/PTN	4
GO:0071514	genetic imprinting	4/2053	23/18722	0.240661554431444	0.438097489863065	KCNQ1/BRCA1/KDM1B/TRIM28	4
GO:0048041	focal adhesion assembly	12/2053	87/18722	0.242442900081905	0.441206369575806	VEGFA/PTK2B/S100A10/LIMS1/NRP1/RHOA/FERMT2/SLC9A1/VCL/CORO1C/PTK2/TRIP6	12
GO:0006575	cellular modified amino acid metabolic process	24/2053	188/18722	0.244168096263147	0.444076561860831	CTSB/GPX1/TYMS/GGH/GSTP1/SOD1/ALDH7A1/DHFR/CLIC1/GATA3/FOLR1/GCLM/SLC19A1/ASS1/PLSCR1/SERINC2/IDH1/PARK7/GCH1/PCYOX1/PLOD2/SHMT1/CKMT1B/GLO1	24
GO:0030308	negative regulation of cell growth	24/2053	188/18722	0.244168096263147	0.444076561860831	BST2/TGFB1/SPP1/FBP1/RBBP7/SEMA4A/BCL6/ARHGAP4/CDA/SEMA6A/PPT1/GJA1/BTG1/NRP1/SEMA6D/SMARCA2/CDKN2A/PHB/RGS2/EI24/HSPA1A/CDKN1A/NDUFA13/DCBLD2	24
GO:1901184	regulation of ERBB signaling pathway	11/2053	79/18722	0.245340457672786	0.446073559405065	NCF1/PLAUR/EGFR/IFI6/RHBDF2/CCDC88A/HBEGF/DGKD/MVP/VPS25/PTPN3	11
GO:0007127	meiosis I	17/2053	129/18722	0.246363172265055	0.447797344316974	TOP2A/RAD51AP1/RAD51/CCNE1/UBB/RAD51C/CKS2/FBXO5/RAD21/CCNE2/MND1/BRCA2/FANCD2/RAD50/PSMC3IP/TOP2B/ING2	17
GO:0014896	muscle hypertrophy	14/2053	104/18722	0.247455298657962	0.449510079306016	CYBA/TNFRSF1B/PARP1/MEF2A/NOTCH1/HAMP/EZH2/CAMK2D/HDAC2/IL6ST/PARP2/RGS2/SLC9A1/LMNA	14
GO:0060419	heart growth	14/2053	104/18722	0.247455298657962	0.449510079306016	MEF2C/DUSP9/RUNX1/CDK1/NOTCH1/HAMP/GJA1/YAP1/PARP2/RGS2/FOXC1/TGFBR3/BASP1/MAPK14	14
GO:0003281	ventricular septum development	10/2053	71/18722	0.247984990799882	0.449822029297282	LRP2/NOTCH1/LMO4/GJA5/SOX4/GATA3/CNTRL/LUZP1/TGFBR3/TBX3	10
GO:0050818	regulation of coagulation	10/2053	71/18722	0.247984990799882	0.449822029297282	CD9/PRDX2/CD36/HPSE/SH2B3/ANXA5/C1QTNF1/UBASH3B/PDGFA/SERPING1	10
GO:0150116	regulation of cell-substrate junction organization	10/2053	71/18722	0.247984990799882	0.449822029297282	VEGFA/S100A10/LIMS1/NRP1/RHOA/FERMT2/SLC9A1/VCL/CORO1C/PTK2	10
GO:0042594	response to starvation	25/2053	197/18722	0.248077623687595	0.449822029297282	ZFP36/PAGE4/UCP2/UPP1/LRRK2/IFI16/SLC2A1/GLUL/PDK4/COMT/HSPA5/HAMP/CTSV/HNRNPA1/HSPA8/PMAIP1/RALB/EIF2AK4/JUN/EIF2AK1/CDKN1A/ATF3/GABARAP/WIPI2/PRKAG2	25
GO:0006633	fatty acid biosynthetic process	21/2053	163/18722	0.248474432331194	0.449822029297282	CD74/ALOX5/HACD3/IL1B/GSTP1/ACSS1/TECR/TBXAS1/PDK4/BRCA1/ACADVL/DEGS1/APOC1/FABP5/NDUFAB1/MID1IP1/ABHD2/PTGES/MGLL/HACD4/PRKAG2	21
GO:0001516	prostaglandin biosynthetic process	5/2053	31/18722	0.248676611863181	0.449822029297282	CD74/IL1B/TBXAS1/FABP5/PTGES	5
GO:0007190	activation of adenylate cyclase activity	5/2053	31/18722	0.248676611863181	0.449822029297282	LGR5/CAP1/ADRB1/LGR4/P2RY11	5
GO:0031114	regulation of microtubule depolymerization	5/2053	31/18722	0.248676611863181	0.449822029297282	CIB1/TPX2/CKAP2/MID1IP1/ARHGEF2	5
GO:0043171	peptide catabolic process	5/2053	31/18722	0.248676611863181	0.449822029297282	CTSH/ENPEP/TPP1/ANPEP/LTA4H	5
GO:0046457	prostanoid biosynthetic process	5/2053	31/18722	0.248676611863181	0.449822029297282	CD74/IL1B/TBXAS1/FABP5/PTGES	5
GO:0048710	regulation of astrocyte differentiation	5/2053	31/18722	0.248676611863181	0.449822029297282	NOTCH1/TREM2/IL6ST/ID2/PRPF19	5
GO:0051569	regulation of histone H3-K4 methylation	5/2053	31/18722	0.248676611863181	0.449822029297282	DNMT1/RTF1/BRCA1/GATA3/KMT2E	5
GO:0061099	negative regulation of protein tyrosine kinase activity	5/2053	31/18722	0.248676611863181	0.449822029297282	PTPRC/LILRB4/MVP/VPS25/NCAPG2	5
GO:0070528	protein kinase C signaling	5/2053	31/18722	0.248676611863181	0.449822029297282	PLEK/VEGFA/MYADM/ADGRG1/DGKD	5
GO:0032886	regulation of microtubule-based process	30/2053	240/18722	0.249361145579407	0.450924313886812	STMN1/RPS3/MET/CATSPER1/NPM1/BRCA1/KLHL42/CLIP1/RHOA/CIB1/TPX2/CKAP2/ARL2/ATF5/TPR/MID1IP1/CFAP20/SKA2/GNAI1/ARHGEF2/HSPA1A/CDK2AP2/CENPJ/SKA3/CHMP4C/PLK2/AKAP9/GPSM2/DEFB1/DRG1	30
GO:0022617	extracellular matrix disassembly	9/2053	63/18722	0.25024510015984	0.451134102437908	CTSS/LCP1/TGFB1/CST3/DPP4/ADAM8/LAMC1/CTSV/MMP15	9
GO:0030510	regulation of BMP signaling pathway	13/2053	96/18722	0.251183615706528	0.451134102437908	SORL1/SKIL/FBN1/LRP2/ENG/NOTCH1/CRIM1/FSTL1/NOTCH2/UBE2D1/CTDSPL2/PPARG/GPC3	13
GO:0003179	heart valve morphogenesis	8/2053	55/18722	0.251917344371713	0.451134102437908	TGFB1/MEF2C/NOTCH1/GJA5/NOTCH2/SOX4/GATA3/EFNA1	8
GO:0008333	endosome to lysosome transport	8/2053	55/18722	0.251917344371713	0.451134102437908	LYST/DENND3/DTX3L/HMGXB4/HOOK2/RHOB/VCP/AKTIP	8
GO:0031113	regulation of microtubule polymerization	8/2053	55/18722	0.251917344371713	0.451134102437908	STMN1/RPS3/MET/CLIP1/ARL2/HSPA1A/AKAP9/DRG1	8
GO:0048016	inositol phosphate-mediated signaling	8/2053	55/18722	0.251917344371713	0.451134102437908	CLEC7A/TNF/HOMER3/CHP1/CIB1/SLC9A1/FHL2/NFAT5	8
GO:0051898	negative regulation of protein kinase B signaling	8/2053	55/18722	0.251917344371713	0.451134102437908	KLF4/ARRB2/DAG1/SH2B3/PHLDA3/CIB1/DLG1/PLEKHA1	8
GO:0046326	positive regulation of glucose import	6/2053	39/18722	0.251943683518625	0.451134102437908	MEF2A/RAP1A/RHOQ/INSR/MAPK14/GPC3	6
GO:0051931	regulation of sensory perception	6/2053	39/18722	0.251943683518625	0.451134102437908	CCL3/PTAFR/COMT/FABP5/SLC9A1/MGLL	6
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	7/2053	47/18722	0.252672257871199	0.451134102437908	CYBA/SOD2/CTSZ/MME/ENPEP/ADRB1/RHOA	7
GO:0035315	hair cell differentiation	7/2053	47/18722	0.252672257871199	0.451134102437908	SOD1/NOTCH1/KCNQ1/MCOLN3/ESRP1/TRIOBP/MYO7A	7
GO:0045601	regulation of endothelial cell differentiation	7/2053	47/18722	0.252672257871199	0.451134102437908	VEGFA/TNF/IL1B/NOTCH1/ID1/BTG1/VCL	7
GO:0101023	vascular endothelial cell proliferation	7/2053	47/18722	0.252672257871199	0.451134102437908	MEF2C/HMGB1/ITGA4/FLT1/STAT3/MDK/PPARG	7
GO:1905562	regulation of vascular endothelial cell proliferation	7/2053	47/18722	0.252672257871199	0.451134102437908	MEF2C/HMGB1/ITGA4/FLT1/STAT3/MDK/PPARG	7
GO:0007519	skeletal muscle tissue development	20/2053	155/18722	0.252894514198568	0.451134102437908	TGFB1/MEF2C/VAMP5/FOS/GPX1/HIVEP3/GPCPD1/NOTCH1/NR2F2/NR4A1/BTG2/UQCC2/RHOA/MYL6/KLF5/GPC1/DMD/ATF3/HOMER1/MAPK14	20
GO:0001845	phagolysosome assembly	3/2053	16/18722	0.25293585343352	0.451134102437908	CORO1A/SYT7/MYO7A	3
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	3/2053	16/18722	0.25293585343352	0.451134102437908	CTSZ/MME/ENPEP	3
GO:0002093	auditory receptor cell morphogenesis	3/2053	16/18722	0.25293585343352	0.451134102437908	SOD1/TRIOBP/MYO7A	3
GO:0002713	negative regulation of B cell mediated immunity	3/2053	16/18722	0.25293585343352	0.451134102437908	CD46/PTPN6/BCL6	3
GO:0002890	negative regulation of immunoglobulin mediated immune response	3/2053	16/18722	0.25293585343352	0.451134102437908	CD46/PTPN6/BCL6	3
GO:0003084	positive regulation of systemic arterial blood pressure	3/2053	16/18722	0.25293585343352	0.451134102437908	CYBA/NR2F2/RHOA	3
GO:0005980	glycogen catabolic process	3/2053	16/18722	0.25293585343352	0.451134102437908	HMGB1/AGL/GAA	3
GO:0006004	fucose metabolic process	3/2053	16/18722	0.25293585343352	0.451134102437908	FUCA1/FUOM/FUT8	3
GO:0006349	regulation of gene expression by genetic imprinting	3/2053	16/18722	0.25293585343352	0.451134102437908	KCNQ1/BRCA1/KDM1B	3
GO:0009074	aromatic amino acid family catabolic process	3/2053	16/18722	0.25293585343352	0.451134102437908	KYNU/IL4I1/QDPR	3
GO:0009299	mRNA transcription	3/2053	16/18722	0.25293585343352	0.451134102437908	FLNA/C5AR1/STAT3	3
GO:0009415	response to water	3/2053	16/18722	0.25293585343352	0.451134102437908	CD9/KRT8/AKR1B1	3
GO:0010919	regulation of inositol phosphate biosynthetic process	3/2053	16/18722	0.25293585343352	0.451134102437908	PLEK/PTAFR/PTK2B	3
GO:0014819	regulation of skeletal muscle contraction	3/2053	16/18722	0.25293585343352	0.451134102437908	C12orf57/NR4A1/DMD	3
GO:0021535	cell migration in hindbrain	3/2053	16/18722	0.25293585343352	0.451134102437908	FLNA/ITGB1/RERE	3
GO:0021783	preganglionic parasympathetic fiber development	3/2053	16/18722	0.25293585343352	0.451134102437908	NRP2/TFAP2A/NRP1	3
GO:0030033	microvillus assembly	3/2053	16/18722	0.25293585343352	0.451134102437908	FXYD5/KLF5/EZR	3
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	3/2053	16/18722	0.25293585343352	0.451134102437908	ITGA5/IL1B/PRKCB	3
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	3/2053	16/18722	0.25293585343352	0.451134102437908	EZH2/RNF8/NELFCD	3
GO:0035751	regulation of lysosomal lumen pH	3/2053	16/18722	0.25293585343352	0.451134102437908	LRRK2/GRN/PPT1	3
GO:0042407	cristae formation	3/2053	16/18722	0.25293585343352	0.451134102437908	IMMT/CHCHD10/AFG3L2	3
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	3/2053	16/18722	0.25293585343352	0.451134102437908	CXCR4/ARRB2/NR2F6	3
GO:0070242	thymocyte apoptotic process	3/2053	16/18722	0.25293585343352	0.451134102437908	ADAM8/EFNA1/GLI3	3
GO:0071391	cellular response to estrogen stimulus	3/2053	16/18722	0.25293585343352	0.451134102437908	RARA/TRIM24/ARID5A	3
GO:0072109	glomerular mesangium development	3/2053	16/18722	0.25293585343352	0.451134102437908	BMP7/NOTCH1/IL6R	3
GO:0090336	positive regulation of brown fat cell differentiation	3/2053	16/18722	0.25293585343352	0.451134102437908	METRNL/BMP7/MAPK14	3
GO:0090520	sphingolipid mediated signaling pathway	3/2053	16/18722	0.25293585343352	0.451134102437908	S1PR4/SPHK1/EZR	3
GO:0097284	hepatocyte apoptotic process	3/2053	16/18722	0.25293585343352	0.451134102437908	KRT18/KRT8/STK4	3
GO:1902570	protein localization to nucleolus	3/2053	16/18722	0.25293585343352	0.451134102437908	GLUL/RAN/NPM1	3
GO:1903236	regulation of leukocyte tethering or rolling	3/2053	16/18722	0.25293585343352	0.451134102437908	ITGA4/PTAFR/CCR2	3
GO:2001212	regulation of vasculogenesis	3/2053	16/18722	0.25293585343352	0.451134102437908	EMP2/RRAS/RAP1A	3
GO:0001843	neural tube closure	12/2053	88/18722	0.25487710244674	0.454326385823066	TGFB1/SPINT1/SPINT2/LRP2/VASP/RPS7/RARA/LMO4/FOLR1/KIF20B/PFN1/COBL	12
GO:0050779	RNA destabilization	12/2053	88/18722	0.25487710244674	0.454326385823066	TNFRSF1B/ZFP36/ZFP36L2/PABPC1/LIN28B/ZFP36L1/HNRNPR/BTG2/EXOSC8/HNRNPD/KHSRP/AGO2	12
GO:0006479	protein methylation	23/2053	181/18722	0.257141328053015	0.457818388224952	DNMT1/SNRPB/RTF1/BRCA1/BTG2/EZH2/BTG1/SUZ12/SNRPD3/SMYD2/GATA3/BRD4/RAB3D/ICMT/KMT5A/KMT2E/DPY30/RIF1/LCMT1/NTMT1/LMNA/FBL/PWP1	23
GO:0008213	protein alkylation	23/2053	181/18722	0.257141328053015	0.457818388224952	DNMT1/SNRPB/RTF1/BRCA1/BTG2/EZH2/BTG1/SUZ12/SNRPD3/SMYD2/GATA3/BRD4/RAB3D/ICMT/KMT5A/KMT2E/DPY30/RIF1/LCMT1/NTMT1/LMNA/FBL/PWP1	23
GO:0008361	regulation of cell size	23/2053	181/18722	0.257141328053015	0.457818388224952	MSN/PLEK/FN1/SPP1/VEGFA/HSP90AB1/SEMA4A/ARHGAP4/NPM1/VAV1/TRPV2/P2RX7/SEMA6A/RDX/NRP1/RHOA/LAMTOR4/GOLGA4/CDK4/TWF2/SEMA6D/KCNN4/VAV3	23
GO:1905952	regulation of lipid localization	23/2053	181/18722	0.257141328053015	0.457818388224952	TSPO/MSR1/SPP1/RETN/TNF/IL1B/CD36/C3/NFKBIA/SYK/TREM2/DBI/HILPDA/PLIN2/APOC1/TRIAP1/ITGAV/FIS1/PTGES/C1QTNF1/ASXL1/LDLRAP1/PPARG	23
GO:0050806	positive regulation of synaptic transmission	21/2053	164/18722	0.25756255583297	0.458432315336049	TYROBP/LILRB2/EGFR/RETN/TNF/APP/CCR2/ARRB2/GLUL/NSG1/MME/PTK2B/ZDHHC12/CX3CR1/STAU1/NRGN/EIF2AK4/PLK2/PTN/CLSTN1/SLC1A3	21
GO:0007422	peripheral nervous system development	11/2053	80/18722	0.258491822787728	0.459949862611615	RUNX1/DAG1/SOD1/CDK1/ITGB4/RUNX3/ISL1/PARD3/GPC1/ADGRG6/NDRG1	11
GO:0010469	regulation of signaling receptor activity	22/2053	173/18722	0.261884095884438	0.465711024098205	NCF1/MEF2C/LILRB4/JAK2/PHLDA2/TNF/APP/CCR2/LRPAP1/IFNGR2/ITGB1/PTK2B/HBEGF/NRP1/HDAC2/PARK7/VPS25/AKAP9/CAPN1/HOMER1/PPARG/NCAPG2	22
GO:0050709	negative regulation of protein secretion	10/2053	72/18722	0.26196245105524	0.465711024098205	UCP2/IL1B/RSAD2/RHBDF2/ERP29/IDH2/KLF7/FRMD4A/HADH/MIDN	10
GO:0051057	positive regulation of small GTPase mediated signal transduction	10/2053	72/18722	0.26196245105524	0.465711024098205	GPR65/LPAR6/ADGRG1/TGM2/NOTCH1/HRAS/NOTCH2/ITGAV/NET1/DYNLT1	10
GO:0016579	protein deubiquitination	18/2053	139/18722	0.262121814936034	0.465856306165937	TNFAIP3/CDK1/USP1/USP48/USP15/USP10/USP27X/PSMD14/USP14/USP3/USP22/PARK7/USP53/USP39/VCP/DESI2/BRCC3/ASXL1	18
GO:0010596	negative regulation of endothelial cell migration	13/2053	97/18722	0.263195793924891	0.467488088676538	TGFB1/MEF2C/HMGB1/KLF4/TNF/SERPINF1/VASH1/NOTCH1/NR2F2/RHOA/RGCC/SP100/PPARG	13
GO:0035335	peptidyl-tyrosine dephosphorylation	13/2053	97/18722	0.263195793924891	0.467488088676538	PTPRC/DUSP1/PGP/PTPN6/PTPN14/DUSP14/DUSP18/PTPRF/DUSP5/PTP4A2/PTPN3/UBASH3B/PTPRU	13
GO:0016126	sterol biosynthetic process	9/2053	64/18722	0.265189467644639	0.469506496871917	SOD1/FDPS/DHCR24/SQLE/FDFT1/PMVK/EBP/CYB5R1/PRKAG2	9
GO:0048247	lymphocyte chemotaxis	9/2053	64/18722	0.265189467644639	0.469506496871917	CCL3L3/CCL3/CCL4/CXCL16/CCR2/CXCL10/ADAM8/PTK2B/GPR183	9
GO:0048857	neural nucleus development	9/2053	64/18722	0.265189467644639	0.469506496871917	ACTB/MBP/HSPA5/RHOA/CALM2/CCDC14/YWHAE/GNB4/BASP1	9
GO:1900076	regulation of cellular response to insulin stimulus	9/2053	64/18722	0.265189467644639	0.469506496871917	SORL1/IL1B/SOCS3/NUCKS1/ATP2B1/PRKCB/KANK1/GNAI2/MYO1C	9
GO:0007041	lysosomal transport	15/2053	114/18722	0.265760204229847	0.469506496871917	LAPTM5/SORL1/PSAP/LRRK2/GRN/LYST/DENND3/HSPA8/DTX3L/HMGXB4/HOOK2/HSPA1A/RHOB/VCP/AKTIP	15
GO:0016486	peptide hormone processing	4/2053	24/18722	0.265762749515461	0.469506496871917	CTSL/CTSZ/MME/ENPEP	4
GO:0030810	positive regulation of nucleotide biosynthetic process	4/2053	24/18722	0.265762749515461	0.469506496871917	TMSB4X/TREM2/STAT3/VCP	4
GO:0032528	microvillus organization	4/2053	24/18722	0.265762749515461	0.469506496871917	FXYD5/TWF2/KLF5/EZR	4
GO:0033032	regulation of myeloid cell apoptotic process	4/2053	24/18722	0.265762749515461	0.469506496871917	MEF2C/IRF7/TCP1/CDKN2A	4
GO:0039531	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	4/2053	24/18722	0.265762749515461	0.469506496871917	OASL/BIRC3/C1QBP/USP15	4
GO:0044321	response to leptin	4/2053	24/18722	0.265762749515461	0.469506496871917	LRP2/CCND1/CCNA2/STAT3	4
GO:0045649	regulation of macrophage differentiation	4/2053	24/18722	0.265762749515461	0.469506496871917	TGFB1/TRIB1/HCLS1/ID2	4
GO:0051000	positive regulation of nitric-oxide synthase activity	4/2053	24/18722	0.265762749515461	0.469506496871917	TNF/PTK2B/DHFR/GCH1	4
GO:0051570	regulation of histone H3-K9 methylation	4/2053	24/18722	0.265762749515461	0.469506496871917	DNMT1/BRCA1/RIF1/LMNA	4
GO:0070935	3'-UTR-mediated mRNA stabilization	4/2053	24/18722	0.265762749515461	0.469506496871917	ZFP36/MYD88/HNRNPA0/MAPK14	4
GO:0071577	zinc ion transmembrane transport	4/2053	24/18722	0.265762749515461	0.469506496871917	SLC39A10/SLC39A1/TRPM2/SLC39A7	4
GO:1900373	positive regulation of purine nucleotide biosynthetic process	4/2053	24/18722	0.265762749515461	0.469506496871917	TMSB4X/TREM2/STAT3/VCP	4
GO:2001026	regulation of endothelial cell chemotaxis	4/2053	24/18722	0.265762749515461	0.469506496871917	TMSB4X/VEGFA/MET/NOTCH1	4
GO:0051260	protein homooligomerization	23/2053	182/18722	0.265897179395129	0.469506496871917	SAMHD1/PYCARD/KCTD12/B2M/GBP5/SOD2/ALOX5AP/VASP/FUS/TK1/ALDOA/RNF213/TRPM2/NLRP1/BLM/SLC1A5/ECT2/RBMX/SHMT1/POLQ/SIGMAR1/KCTD1/ALAD	23
GO:0060401	cytosolic calcium ion transport	23/2053	182/18722	0.265897179395129	0.469506496871917	PTPRC/CORO1A/CCL3/CYBA/LYN/SLC8A1/CXCL10/PTPN6/ATP2B1/PTK2B/TRPV2/P2RX7/CAMK2D/TRPM2/CALM2/MCOLN3/VDAC1/AFG3L2/YWHAE/MCUR1/DMD/FKBP1A/UBASH3B	23
GO:0016485	protein processing	28/2053	225/18722	0.266307995208793	0.47009354847095	CTSS/SRGN/PYCARD/LRRK2/CTSL/PERP/CASP1/IFI16/PARP1/RUNX1/CTSH/CTSZ/CARD16/MME/ADAM8/DHCR24/ENPEP/ASPH/SPCS2/BCL2L12/BAG2/STOML2/AFG3L2/BAD/PRSS12/PISD/GLI3/PMPCB	28
GO:0071772	response to BMP	21/2053	165/18722	0.266779610305741	0.470649121386195	TGFB1/SORL1/SPINT1/SKIL/SPINT2/FBN1/LRP2/BMP7/ENG/NOTCH1/CRIM1/FSTL1/USP15/NOTCH2/GATA3/UBE2D1/TGFBR3/SMAD5/CTDSPL2/PPARG/GPC3	21
GO:0071773	cellular response to BMP stimulus	21/2053	165/18722	0.266779610305741	0.470649121386195	TGFB1/SORL1/SPINT1/SKIL/SPINT2/FBN1/LRP2/BMP7/ENG/NOTCH1/CRIM1/FSTL1/USP15/NOTCH2/GATA3/UBE2D1/TGFBR3/SMAD5/CTDSPL2/PPARG/GPC3	21
GO:0050853	B cell receptor signaling pathway	17/2053	131/18722	0.266942792679149	0.470798576153703	MNDA/PTPRC/NCKAP1L/LYN/LAT2/MEF2C/CD300A/BTK/SYK/PTPN6/NFAM1/SLC39A10/CMTM3/PRKCB/BCAR1/VAV3/PLEKHA1	17
GO:0050905	neuromuscular process	19/2053	148/18722	0.267189436130639	0.471095097497454	APP/RCSD1/C12orf57/KCNQ1/TNNI2/NR4A1/PNKD/TPP1/IGDCC3/TMEM150C/GCH1/DMD/GAA/CHRNB1/HEXB/HOMER1/RAC3/SLC1A3/MYO7A	19
GO:0060606	tube closure	12/2053	89/18722	0.267531127797617	0.471558979666775	TGFB1/SPINT1/SPINT2/LRP2/VASP/RPS7/RARA/LMO4/FOLR1/KIF20B/PFN1/COBL	12
GO:0048008	platelet-derived growth factor receptor signaling pathway	8/2053	56/18722	0.268016281454764	0.472275385823373	TXNIP/JAK2/VEGFA/NRP1/ARID5B/BCAR1/PDGFA/PLEKHA1	8
GO:0002686	negative regulation of leukocyte migration	7/2053	48/18722	0.270185732736744	0.474470012246307	CD300A/DUSP1/HMOX1/PTGER4/IL27RA/DPP4/RIN3	7
GO:0042149	cellular response to glucose starvation	7/2053	48/18722	0.270185732736744	0.474470012246307	UPP1/IFI16/SLC2A1/HSPA5/HNRNPA1/PMAIP1/PRKAG2	7
GO:0045912	negative regulation of carbohydrate metabolic process	7/2053	48/18722	0.270185732736744	0.474470012246307	PLEK/TGFB1/FBP1/PGP/DDIT4/STAT3/MIDN	7
GO:0061647	histone H3-K9 modification	7/2053	48/18722	0.270185732736744	0.474470012246307	DNMT1/BRCA1/CHEK1/GATA3/RIF1/ZNF451/LMNA	7
GO:0006335	DNA replication-dependent nucleosome assembly	5/2053	32/18722	0.270368828645021	0.474470012246307	NASP/ASF1B/RBBP4/HAT1/CHAF1A	5
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	5/2053	32/18722	0.270368828645021	0.474470012246307	SUPT16H/EZH2/BRD4/RNF8/NELFCD	5
GO:0034723	DNA replication-dependent nucleosome organization	5/2053	32/18722	0.270368828645021	0.474470012246307	NASP/ASF1B/RBBP4/HAT1/CHAF1A	5
GO:0048841	regulation of axon extension involved in axon guidance	5/2053	32/18722	0.270368828645021	0.474470012246307	VEGFA/SEMA4A/SEMA6A/NRP1/SEMA6D	5
GO:0060317	cardiac epithelial to mesenchymal transition	5/2053	32/18722	0.270368828645021	0.474470012246307	ENG/NOTCH1/EFNA1/TGFBR3/TBX3	5
GO:0060914	heart formation	5/2053	32/18722	0.270368828645021	0.474470012246307	MEF2C/LRP2/NOTCH1/ISL1/FOLR1	5
GO:0072525	pyridine-containing compound biosynthetic process	5/2053	32/18722	0.270368828645021	0.474470012246307	NAMPT/KYNU/QPRT/PARP9/IDH2	5
GO:1901532	regulation of hematopoietic progenitor cell differentiation	5/2053	32/18722	0.270368828645021	0.474470012246307	SPI1/PRKDC/NOTCH1/FOXC1/HSPA9	5
GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	5/2053	32/18722	0.270368828645021	0.474470012246307	LRRK2/ERP29/PMAIP1/PARK7/HSPA1A	5
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	5/2053	32/18722	0.270368828645021	0.474470012246307	LGALS9/HMGB1/RUNX1/BCL6/RUNX3	5
GO:0006766	vitamin metabolic process	14/2053	106/18722	0.270524774360955	0.474604867299922	SLC2A3/LRP2/TNF/SLC2A1/DHFR/FOLR1/SLC19A1/SLC52A1/SHMT1/MMAB/VKORC1/SLC19A3/MTR/CD320	14
GO:0031111	negative regulation of microtubule polymerization or depolymerization	6/2053	40/18722	0.271250568690285	0.475044778792093	STMN1/CIB1/TPX2/CKAP2/MID1IP1/ARHGEF2	6
GO:0044275	cellular carbohydrate catabolic process	6/2053	40/18722	0.271250568690285	0.475044778792093	HMGB1/AOAH/AGL/GAA/GK/ENOSF1	6
GO:0045777	positive regulation of blood pressure	6/2053	40/18722	0.271250568690285	0.475044778792093	CYBA/NR2F2/ADH5/ADRB1/RHOA/ID2	6
GO:0046365	monosaccharide catabolic process	6/2053	40/18722	0.271250568690285	0.475044778792093	HK3/HK2/LRP5/FUT8/NUDT5/BAD	6
GO:0055069	zinc ion homeostasis	6/2053	40/18722	0.271250568690285	0.475044778792093	S100A8/MT1X/S100A9/SLC39A10/MT2A/SLC39A7	6
GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	6/2053	40/18722	0.271250568690285	0.475044778792093	SLC25A5/BNIP3L/CHCHD10/HSPA1A/NMT1/BNIP3	6
GO:0070646	protein modification by small protein removal	20/2053	157/18722	0.271838301010541	0.475861592345184	HINT1/TNFAIP3/CDK1/USP1/USP48/USP15/USP10/USP27X/PSMD14/USP14/USP3/USP22/PARK7/USP53/COPS3/USP39/VCP/DESI2/BRCC3/ASXL1	20
GO:2001021	negative regulation of response to DNA damage stimulus	11/2053	81/18722	0.271875589759882	0.475861592345184	CD74/CD44/RPS3/RMI2/TRIAP1/FBXO5/MAGEF1/ERCC1/ING2/RIF1/POLQ	11
GO:0015748	organophosphate ester transport	18/2053	140/18722	0.272239104849149	0.476220008482476	NPC2/SLC25A5/DBI/LRRC8C/P2RX7/SLC29A1/GJA1/APOC1/TRIAP1/SLC25A36/SLC25A4/SLC19A1/PLSCR1/TMEM30B/KCNN4/SLC25A17/PITPNB/SLC25A6	18
GO:0046165	alcohol biosynthetic process	18/2053	140/18722	0.272239104849149	0.476220008482476	PLEK/ISYNA1/PGP/PTAFR/SOD1/FDPS/PTK2B/DHCR24/DHFR/AKR1B1/SPHK1/FDFT1/PMVK/IMPA2/EBP/PARK7/GCH1/QDPR	18
GO:0061448	connective tissue development	31/2053	252/18722	0.274676705301888	0.480343990618282	TIMP1/CD44/SPI1/TGFB1/SORL1/TGFBI/CRIP1/MEF2C/EFEMP1/TYMS/RUNX1/RARA/BMP7/NOTCH1/IL6R/TRPS1/SERPINH1/RUNX3/UBB/SULF2/KLF7/CDK4/LRP5/SCIN/ARID5B/PGRMC2/GLI3/MDK/SMAD5/ITGB8/MAPK14	31
GO:0006790	sulfur compound metabolic process	41/2053	339/18722	0.274948300209679	0.480678846520418	GPX1/GSTP1/KYNU/SLC26A2/SOD1/TSTD1/MPC2/ACSS1/TECR/PDK4/COMT/CHPF/STAT5A/PPT1/SULT1A1/ADI1/NUDT8/CDO1/SLC25A1/SMS/CLIC1/MTAP/CHST15/GLRX5/ACSL4/GCLM/TPST2/CHST14/PMVK/DSE/PDHA1/IDH1/PARK7/CIAO1/NUBP2/ISCA1/SLC19A3/HSPA9/MTR/ENOPH1/GLO1	41
GO:0003170	heart valve development	9/2053	65/18722	0.280397695223307	0.489492630590585	TNFRSF1B/TGFB1/MEF2C/NOTCH1/GJA5/NOTCH2/SOX4/GATA3/EFNA1	9
GO:0038034	signal transduction in absence of ligand	9/2053	65/18722	0.280397695223307	0.489492630590585	BCL2A1/PRDX2/TNF/IL1B/IFI6/MCL1/ITGAV/HSPA1A/BAD	9
GO:0045682	regulation of epidermis development	9/2053	65/18722	0.280397695223307	0.489492630590585	ZFP36/NOTCH1/ZFP36L1/EZH2/KLF7/VDR/ESRP1/FOXC1/KRT10	9
GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	9/2053	65/18722	0.280397695223307	0.489492630590585	BCL2A1/PRDX2/TNF/IL1B/IFI6/MCL1/ITGAV/HSPA1A/BAD	9
GO:1902475	L-alpha-amino acid transmembrane transport	9/2053	65/18722	0.280397695223307	0.489492630590585	SLC7A7/SLC38A1/ITGB1/SLC1A5/RGS2/SLC7A6/SLC38A9/SLC3A2/SLC1A3	9
GO:0036503	ERAD pathway	14/2053	107/18722	0.282326566659929	0.491471328476048	HSP90B1/CALR/CCDC47/HSPA5/FBXO6/UBXN4/USP14/SVIP/SDF2L1/SGTB/VCP/DNAJB14/DNAJB9/UBE4B	14
GO:0051341	regulation of oxidoreductase activity	14/2053	107/18722	0.282326566659929	0.491471328476048	CYBA/EGFR/LRRK2/TNF/IL1B/PTK2B/DHFR/DDAH2/PHB2/GNAI2/VDR/PARK7/GCH1/COX17	14
GO:0071868	cellular response to monoamine stimulus	14/2053	107/18722	0.282326566659929	0.491471328476048	FLNA/LRRK2/APP/GNAS/ARRB2/TGM2/NSG1/KCNQ1/GNA15/ID1/HRH2/HDAC2/GNA11/SLC9A1	14
GO:0071870	cellular response to catecholamine stimulus	14/2053	107/18722	0.282326566659929	0.491471328476048	FLNA/LRRK2/APP/GNAS/ARRB2/TGM2/NSG1/KCNQ1/GNA15/ID1/HRH2/HDAC2/GNA11/SLC9A1	14
GO:0007411	axon guidance	28/2053	227/18722	0.282329957574293	0.491471328476048	RAC2/VEGFA/PLXNC1/APP/VASP/NRP2/DAG1/BSG/BMP7/LAMA5/ALCAM/SEMA4A/NOTCH1/SEMA6A/NRP1/KLF7/ISL1/NOTCH2/GATA3/EPHB4/SEMA6D/EFNA1/SIAH1/RHOG/PALLD/GLI3/PTK2/RPS6KA5	28
GO:0055001	muscle cell development	23/2053	184/18722	0.283743756170488	0.491471328476048	SLC8A1/GPX1/VEGFA/CSRP2/MEF2A/CDK1/ITGB1/ENG/NOTCH1/HAMP/KRT8/ISL1/PARP2/AFG3L2/OBSL1/RGS2/FHL2/DMD/CHRNB1/LMNA/TBX3/HOMER1/ACTN4	23
GO:0003184	pulmonary valve morphogenesis	3/2053	17/18722	0.284070427859156	0.491471328476048	NOTCH1/GJA5/NOTCH2	3
GO:0006390	mitochondrial transcription	3/2053	17/18722	0.284070427859156	0.491471328476048	TFAM/MRPL12/CHCHD10	3
GO:0007379	segment specification	3/2053	17/18722	0.284070427859156	0.491471328476048	MAFB/IRX2/COBL	3
GO:0009251	glucan catabolic process	3/2053	17/18722	0.284070427859156	0.491471328476048	HMGB1/AGL/GAA	3
GO:0010715	regulation of extracellular matrix disassembly	3/2053	17/18722	0.284070427859156	0.491471328476048	TGFB1/CST3/DPP4	3
GO:0020027	hemoglobin metabolic process	3/2053	17/18722	0.284070427859156	0.491471328476048	KLF4/SLC25A37/EIF2AK1	3
GO:0021756	striatum development	3/2053	17/18722	0.284070427859156	0.491471328476048	LRRK2/CNTNAP2/ZSWIM6	3
GO:0030002	cellular anion homeostasis	3/2053	17/18722	0.284070427859156	0.491471328476048	TBXAS1/KCNQ1/KCNE3	3
GO:0030322	stabilization of membrane potential	3/2053	17/18722	0.284070427859156	0.491471328476048	KCNK6/KCNN4/CHCHD10	3
GO:0031445	regulation of heterochromatin assembly	3/2053	17/18722	0.284070427859156	0.491471328476048	DNMT1/TPR/TRIM28	3
GO:0032048	cardiolipin metabolic process	3/2053	17/18722	0.284070427859156	0.491471328476048	PHB2/STOML2/DNAJC19	3
GO:0033151	V(D)J recombination	3/2053	17/18722	0.284070427859156	0.491471328476048	HMGB1/HMGB2/PRKDC	3
GO:0035729	cellular response to hepatocyte growth factor stimulus	3/2053	17/18722	0.284070427859156	0.491471328476048	NRP1/GCLM/BCAR1	3
GO:0043117	positive regulation of vascular permeability	3/2053	17/18722	0.284070427859156	0.491471328476048	TGFB1/VEGFA/TJP1	3
GO:0043968	histone H2A acetylation	3/2053	17/18722	0.284070427859156	0.491471328476048	MORF4L2/YEATS4/ACTL6A	3
GO:0044539	long-chain fatty acid import into cell	3/2053	17/18722	0.284070427859156	0.491471328476048	CD36/SLC2A1/SLC27A2	3
GO:0045198	establishment of epithelial cell apical/basal polarity	3/2053	17/18722	0.284070427859156	0.491471328476048	MSN/FAT1/RHOA	3
GO:0051797	regulation of hair follicle development	3/2053	17/18722	0.284070427859156	0.491471328476048	TNF/HPSE/FERMT1	3
GO:0055119	relaxation of cardiac muscle	3/2053	17/18722	0.284070427859156	0.491471328476048	SLC8A1/CAMK2D/RGS2	3
GO:0061298	retina vasculature development in camera-type eye	3/2053	17/18722	0.284070427859156	0.491471328476048	NRP1/LRP5/COL4A1	3
GO:0071371	cellular response to gonadotropin stimulus	3/2053	17/18722	0.284070427859156	0.491471328476048	NOTCH1/CCNA2/GCLM	3
GO:0090036	regulation of protein kinase C signaling	3/2053	17/18722	0.284070427859156	0.491471328476048	VEGFA/MYADM/DGKD	3
GO:0120261	regulation of heterochromatin organization	3/2053	17/18722	0.284070427859156	0.491471328476048	DNMT1/TPR/TRIM28	3
GO:0140354	lipid import into cell	3/2053	17/18722	0.284070427859156	0.491471328476048	CD36/SLC2A1/SLC27A2	3
GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II	3/2053	17/18722	0.284070427859156	0.491471328476048	TGFB1/LILRB4/PPARG	3
GO:0050879	multicellular organismal movement	8/2053	57/18722	0.284399342069625	0.491756787440274	RCSD1/C12orf57/TNNI2/NR4A1/DMD/GAA/CHRNB1/HOMER1	8
GO:0050881	musculoskeletal movement	8/2053	57/18722	0.284399342069625	0.491756787440274	RCSD1/C12orf57/TNNI2/NR4A1/DMD/GAA/CHRNB1/HOMER1	8
GO:0046395	carboxylic acid catabolic process	29/2053	236/18722	0.285040245849516	0.492722983318092	SDS/GCSH/KYNU/SLC27A2/GLUL/ECI1/QPRT/IL4I1/ECHS1/DDAH2/ACADVL/GLDC/SDSL/ECHDC2/ETFB/NUDT8/CDO1/HADH/OAT/ETFA/ACAT2/ABHD2/QDPR/ECI2/SHMT1/SLC25A17/ECH1/PPAT/ENOSF1	29
GO:0060395	SMAD protein signal transduction	11/2053	82/18722	0.285471796354035	0.493326837017342	VIM/TGFB1/FOS/JAK2/PARP1/BMP7/RBPMS/SPTBN1/JUN/SMAD5/PPARG	11
GO:0017148	negative regulation of translation	30/2053	245/18722	0.287596721010419	0.496855838198247	ZFP36/ZFP36L2/TYMS/RPS3/PABPC1/RARA/CALR/ZFP36L1/DHFR/HNRNPR/BTG2/IGF2BP3/EXOSC8/RPL13A/STAT3/HNRNPD/KHSRP/TPR/EIF2AK4/NCL/RGS2/EIF2AK1/AGO2/SHMT1/MALSU1/TIA1/PURA/EIF4G1/YBX1/GAPDH	30
GO:0003300	cardiac muscle hypertrophy	13/2053	99/18722	0.287788556920968	0.496994242133599	TNFRSF1B/PARP1/MEF2A/NOTCH1/HAMP/EZH2/CAMK2D/HDAC2/IL6ST/PARP2/RGS2/SLC9A1/LMNA	13
GO:0018205	peptidyl-lysine modification	45/2053	376/18722	0.287883956939047	0.496994242133599	SPI1/HINT1/IL1B/GCSH/TGM2/DNMT1/RTF1/MORF4L2/BRCA1/HINT2/SET/EZH2/CHEK1/HAT1/ISL1/SUZ12/SOX4/HDAC2/BRD7/SMYD2/GATA3/CBX4/BRD4/NDUFAB1/BRCA2/POLE3/GNL3/SAE1/EID1/USP22/KMT5A/PARK7/KMT2E/DPY30/PLOD2/RIF1/ZNF451/PHF20/TRIM28/YEATS4/ACTL6A/LMNA/RPS6KA5/PWP1/MBD3	45
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	7/2053	49/18722	0.288008163316421	0.496994242133599	TGFB1/BMP7/ENG/RBPMS/SDCBP/TTK/PPARG	7
GO:0060986	endocrine hormone secretion	7/2053	49/18722	0.288008163316421	0.496994242133599	RETN/IL1B/KCNQ1/GJA1/GATA3/C1QTNF1/TBX3	7
GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process	17/2053	133/18722	0.288118483632784	0.497041662391232	LAPTM5/LRRK2/PLK3/TREM2/PTK2B/PSMC3/TRIB1/PSMC1/BAG2/PSMC2/MAGEF1/TMTC3/HSPA1A/VCP/PLK2/GABARAP/PTK2	17
GO:0097485	neuron projection guidance	28/2053	228/18722	0.290472549864459	0.50052609472527	RAC2/VEGFA/PLXNC1/APP/VASP/NRP2/DAG1/BSG/BMP7/LAMA5/ALCAM/SEMA4A/NOTCH1/SEMA6A/NRP1/KLF7/ISL1/NOTCH2/GATA3/EPHB4/SEMA6D/EFNA1/SIAH1/RHOG/PALLD/GLI3/PTK2/RPS6KA5	28
GO:1900371	regulation of purine nucleotide biosynthetic process	6/2053	41/18722	0.290897901330141	0.50052609472527	TMSB4X/PARP1/TREM2/PDK4/STAT3/VCP	6
GO:0000244	spliceosomal tri-snRNP complex assembly	4/2053	25/18722	0.291306187130107	0.50052609472527	LSM2/SRSF10/PRPF8/PRPF19	4
GO:0010842	retina layer formation	4/2053	25/18722	0.291306187130107	0.50052609472527	TFAP2A/AHI1/OBSL1/FJX1	4
GO:0015012	heparan sulfate proteoglycan biosynthetic process	4/2053	25/18722	0.291306187130107	0.50052609472527	EXTL2/DSE/B3GAT3/HS6ST2	4
GO:0030318	melanocyte differentiation	4/2053	25/18722	0.291306187130107	0.50052609472527	ZEB2/MEF2C/GNA11/GLI3	4
GO:0032878	regulation of establishment or maintenance of cell polarity	4/2053	25/18722	0.291306187130107	0.50052609472527	PTK2B/KANK1/GATA3/KIF20B	4
GO:0046949	fatty-acyl-CoA biosynthetic process	4/2053	25/18722	0.291306187130107	0.50052609472527	TECR/PPT1/SLC25A1/ACSL4	4
GO:0050995	negative regulation of lipid catabolic process	4/2053	25/18722	0.291306187130107	0.50052609472527	SORL1/TNF/IL1B/APOC1	4
GO:0061436	establishment of skin barrier	4/2053	25/18722	0.291306187130107	0.50052609472527	STMN1/MET/CLDN4/LSR	4
GO:0086013	membrane repolarization during cardiac muscle cell action potential	4/2053	25/18722	0.291306187130107	0.50052609472527	FLNA/KCNQ1/KCNE3/YWHAE	4
GO:1900078	positive regulation of cellular response to insulin stimulus	4/2053	25/18722	0.291306187130107	0.50052609472527	SORL1/NUCKS1/GNAI2/MYO1C	4
GO:1903055	positive regulation of extracellular matrix organization	4/2053	25/18722	0.291306187130107	0.50052609472527	TGFB1/RUNX1/DAG1/RGCC	4
GO:1905564	positive regulation of vascular endothelial cell proliferation	4/2053	25/18722	0.291306187130107	0.50052609472527	HMGB1/ITGA4/STAT3/MDK	4
GO:0008544	epidermis development	39/2053	324/18722	0.291530911034672	0.500768813686811	TXNIP/HLA-DRB1/ZFP36/WAS/KLF4/EGFR/TNF/DSP/SOD1/LAMA5/NOTCH1/ZFP36L1/HPSE/SVEP1/CST6/KCNQ1/LGR5/AGPAT2/EZH2/FERMT1/KLF7/FABP5/HDAC2/MCOLN3/VDR/CSTA/LGR4/YAP1/ESRP1/TFDP1/PALLD/STS/STK4/FOXC1/KRT10/TRIOBP/PDGFA/YBX1/MYO7A	39
GO:0010737	protein kinase A signaling	5/2053	33/18722	0.29244339085145	0.501331527173913	LCP1/LRRK2/PDE4A/RDX/EZR	5
GO:0019362	pyridine nucleotide metabolic process	5/2053	33/18722	0.29244339085145	0.501331527173913	NAMPT/KYNU/QPRT/PARP9/IDH2	5
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	5/2053	33/18722	0.29244339085145	0.501331527173913	ITGA5/IL1B/HHEX/PRKCB/EPN2	5
GO:0046496	nicotinamide nucleotide metabolic process	5/2053	33/18722	0.29244339085145	0.501331527173913	NAMPT/KYNU/QPRT/PARP9/IDH2	5
GO:0048333	mesodermal cell differentiation	5/2053	33/18722	0.29244339085145	0.501331527173913	KLF4/ITGB1/ITGB4/GJA1/KDM6B	5
GO:0071295	cellular response to vitamin	5/2053	33/18722	0.29244339085145	0.501331527173913	ATP2B1/VDR/FOLR1/TRIM24/PTN	5
GO:0150117	positive regulation of cell-substrate junction organization	5/2053	33/18722	0.29244339085145	0.501331527173913	VEGFA/S100A10/LIMS1/NRP1/FERMT2	5
GO:0002040	sprouting angiogenesis	23/2053	185/18722	0.292823658895838	0.501840032383613	HMGB1/KLF4/VEGFA/ITGA5/KLF2/ALOX5/HMOX1/JAK1/GLUL/ITGB1/NOTCH1/PTK2B/NR4A1/SEMA6A/RNF213/NRP1/RHOA/CIB1/EPN2/EPHB4/TJP1/PLK2/E2F7	23
GO:0002065	columnar/cuboidal epithelial cell differentiation	12/2053	91/18722	0.29343087193071	0.502593557403443	TYMS/CEBPB/RARA/NOTCH1/RHEB/SOX4/IL6ST/YAP1/CDK6/KLF5/BAD/CDKN1A	12
GO:0006885	regulation of pH	12/2053	91/18722	0.29343087193071	0.502593557403443	SLC11A1/LRRK2/GRN/HVCN1/PDK4/PPT1/CHP1/DMXL2/SLC9A1/ATP6V1B1/TCIRG1/ATP6V0E1	12
GO:0019229	regulation of vasoconstriction	9/2053	66/18722	0.295840399584011	0.504946412967957	EGFR/DOCK4/TBXAS1/ATP2B1/ICAM1/GJA1/HRH2/GJA5/RHOA	9
GO:0030193	regulation of blood coagulation	9/2053	66/18722	0.295840399584011	0.504946412967957	CD9/PRDX2/CD36/HPSE/SH2B3/C1QTNF1/UBASH3B/PDGFA/SERPING1	9
GO:0046626	regulation of insulin receptor signaling pathway	9/2053	66/18722	0.295840399584011	0.504946412967957	SORL1/IL1B/SOCS3/NUCKS1/PRKCB/KANK1/GNAI2/CCND3/CDK4	9
GO:0034470	ncRNA processing	47/2053	395/18722	0.296953888064134	0.504946412967957	RPS21/ISG20/PA2G4/RPS17/RPS7/RPS27/PRKDC/RPS16/RPS14/RPL5/LIN28B/RPL7A/POP7/EXOSC8/RPS19/TRMT1/NOP56/RPL35/NHP2/RPL10A/STAT3/POLR3K/NOP58/RPL14/TSEN34/RBFA/RPS6/RPS8/SNU13/MRPL1/RPL7/HNRNPA2B1/IMP3/WDR18/SBDS/DDX1/KRR1/BRIX1/AGO2/WBP11/RPS25/DDX18/FBL/PWP1/TOE1/MRTO4/BMS1	47
GO:0030902	hindbrain development	19/2053	151/18722	0.297209823193777	0.504946412967957	AIF1/FLNA/MAFB/C5AR1/WLS/BMP7/ITGB1/HSPA5/EZH2/PSMG1/UQCRQ/SLC6A4/HNRNPD/AHI1/ATF5/RERE/FOXC1/MDK/PTN	19
GO:0030324	lung development	22/2053	177/18722	0.29870418664378	0.504946412967957	HMGB1/EGFR/VEGFA/KLF2/TNF/CTSH/CTSZ/DAG1/MME/LAMA5/NOTCH1/HSPB11/EPAS1/DLG5/LIPA/YAP1/GLI3/PTN/DPPA4/PDGFA/ASXL1/GPC3	22
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	17/2053	134/18722	0.298906816340046	0.504946412967957	LRRK2/PLK3/HSP90AB1/PBK/TRIB1/SMARCC1/SDCBP/USP14/SVIP/PARK7/COMMD1/RAD23B/HSPA1A/CDK2/VCP/PLK2/GABARAP	17
GO:0060541	respiratory system development	25/2053	203/18722	0.299077323000951	0.504946412967957	HMGB1/EGFR/VEGFA/KLF2/TNF/CTSH/CTSZ/DAG1/MME/RARA/LAMA5/NOTCH1/HSPB11/EPAS1/DLG5/ASS1/LIPA/YAP1/GLI3/PTN/DPPA4/BASP1/PDGFA/ASXL1/GPC3	25
GO:0046785	microtubule polymerization	11/2053	83/18722	0.299260040451316	0.504946412967957	STMN1/RPS3/MET/CLIP1/FBXO5/TPX2/ARL2/HSPA1A/CENPJ/AKAP9/DRG1	11
GO:0002931	response to ischemia	8/2053	58/18722	0.301029750473465	0.504946412967957	CSF1R/HSPD1/TREM2/P2RX7/HK2/GJA1/CX3CR1/CIB1	8
GO:0043506	regulation of JUN kinase activity	8/2053	58/18722	0.301029750473465	0.504946412967957	TNF/GSTP1/FGD2/RPS3/TLR6/SYK/PTK2B/MAP3K4	8
GO:0045604	regulation of epidermal cell differentiation	8/2053	58/18722	0.301029750473465	0.504946412967957	ZFP36/NOTCH1/ZFP36L1/EZH2/KLF7/VDR/ESRP1/FOXC1	8
GO:0000255	allantoin metabolic process	2/2053	10/18722	0.30145300854187	0.504946412967957	PNP/DNPH1	2
GO:0001553	luteinization	2/2053	10/18722	0.30145300854187	0.504946412967957	RETN/PLEKHA1	2
GO:0003163	sinoatrial node development	2/2053	10/18722	0.30145300854187	0.504946412967957	ISL1/TBX3	2
GO:0005984	disaccharide metabolic process	2/2053	10/18722	0.30145300854187	0.504946412967957	FBP1/GAA	2
GO:0006222	UMP biosynthetic process	2/2053	10/18722	0.30145300854187	0.504946412967957	UPP1/UMPS	2
GO:0006228	UTP biosynthetic process	2/2053	10/18722	0.30145300854187	0.504946412967957	NME4/NME1	2
GO:0006283	transcription-coupled nucleotide-excision repair	2/2053	10/18722	0.30145300854187	0.504946412967957	POLR2I/HMGN1	2
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	2/2053	10/18722	0.30145300854187	0.504946412967957	TSEN34/DDX1	2
GO:0006560	proline metabolic process	2/2053	10/18722	0.30145300854187	0.504946412967957	OAT/PYCR2	2
GO:0006735	NADH regeneration	2/2053	10/18722	0.30145300854187	0.504946412967957	HK3/HK2	2
GO:0009169	purine ribonucleoside monophosphate catabolic process	2/2053	10/18722	0.30145300854187	0.504946412967957	PNP/AMPD3	2
GO:0009170	purine deoxyribonucleoside monophosphate metabolic process	2/2053	10/18722	0.30145300854187	0.504946412967957	PNP/DNPH1	2
GO:0009174	pyrimidine ribonucleoside monophosphate biosynthetic process	2/2053	10/18722	0.30145300854187	0.504946412967957	UPP1/UMPS	2
GO:0009396	folic acid-containing compound biosynthetic process	2/2053	10/18722	0.30145300854187	0.504946412967957	DHFR/GCH1	2
GO:0010728	regulation of hydrogen peroxide biosynthetic process	2/2053	10/18722	0.30145300854187	0.504946412967957	SOD2/STAT3	2
GO:0010992	ubiquitin recycling	2/2053	10/18722	0.30145300854187	0.504946412967957	UBE2C/UBE2S	2
GO:0014041	regulation of neuron maturation	2/2053	10/18722	0.30145300854187	0.504946412967957	LRRK2/RAC3	2
GO:0015911	long-chain fatty acid import across plasma membrane	2/2053	10/18722	0.30145300854187	0.504946412967957	CD36/SLC2A1	2
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	2/2053	10/18722	0.30145300854187	0.504946412967957	P4HB/PRDX4	2
GO:0019062	virion attachment to host cell	2/2053	10/18722	0.30145300854187	0.504946412967957	HSP90AB1/ICAM1	2
GO:0021562	vestibulocochlear nerve development	2/2053	10/18722	0.30145300854187	0.504946412967957	NRP2/NRP1	2
GO:0030214	hyaluronan catabolic process	2/2053	10/18722	0.30145300854187	0.504946412967957	CD44/TGFB1	2
GO:0030388	fructose 1,6-bisphosphate metabolic process	2/2053	10/18722	0.30145300854187	0.504946412967957	FBP1/ALDOA	2
GO:0030638	polyketide metabolic process	2/2053	10/18722	0.30145300854187	0.504946412967957	AKR7A2/AKR1B1	2
GO:0030647	aminoglycoside antibiotic metabolic process	2/2053	10/18722	0.30145300854187	0.504946412967957	AKR7A2/AKR1B1	2
GO:0031125	rRNA 3'-end processing	2/2053	10/18722	0.30145300854187	0.504946412967957	RPS21/EXOSC8	2
GO:0033131	regulation of glucokinase activity	2/2053	10/18722	0.30145300854187	0.504946412967957	BAD/MIDN	2
GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway	2/2053	10/18722	0.30145300854187	0.504946412967957	NAMPT/PARP9	2
GO:0034756	regulation of iron ion transport	2/2053	10/18722	0.30145300854187	0.504946412967957	B2M/HAMP	2
GO:0035646	endosome to melanosome transport	2/2053	10/18722	0.30145300854187	0.504946412967957	RAB32/CD63	2
GO:0035747	natural killer cell chemotaxis	2/2053	10/18722	0.30145300854187	0.504946412967957	CCL3/CCL4	2
GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	2/2053	10/18722	0.30145300854187	0.504946412967957	SULF2/GATA3	2
GO:0035999	tetrahydrofolate interconversion	2/2053	10/18722	0.30145300854187	0.504946412967957	TYMS/SHMT1	2
GO:0040015	negative regulation of multicellular organism growth	2/2053	10/18722	0.30145300854187	0.504946412967957	PLAC8/ADRB1	2
GO:0042996	regulation of Golgi to plasma membrane protein transport	2/2053	10/18722	0.30145300854187	0.504946412967957	CSK/GOPC	2
GO:0043485	endosome to pigment granule transport	2/2053	10/18722	0.30145300854187	0.504946412967957	RAB32/CD63	2
GO:0044598	doxorubicin metabolic process	2/2053	10/18722	0.30145300854187	0.504946412967957	AKR7A2/AKR1B1	2
GO:0045792	negative regulation of cell size	2/2053	10/18722	0.30145300854187	0.504946412967957	RDX/RHOA	2
GO:0048755	branching morphogenesis of a nerve	2/2053	10/18722	0.30145300854187	0.504946412967957	LRRK2/RERE	2
GO:0048757	pigment granule maturation	2/2053	10/18722	0.30145300854187	0.504946412967957	RAB32/CD63	2
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	2/2053	10/18722	0.30145300854187	0.504946412967957	SERPINF1/NOTCH1	2
GO:0060947	cardiac vascular smooth muscle cell differentiation	2/2053	10/18722	0.30145300854187	0.504946412967957	VEGFA/NOTCH1	2
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	2/2053	10/18722	0.30145300854187	0.504946412967957	UCP2/KLF7	2
GO:0061621	canonical glycolysis	2/2053	10/18722	0.30145300854187	0.504946412967957	HK3/HK2	2
GO:0061718	glucose catabolic process to pyruvate	2/2053	10/18722	0.30145300854187	0.504946412967957	HK3/HK2	2
GO:0070099	regulation of chemokine-mediated signaling pathway	2/2053	10/18722	0.30145300854187	0.504946412967957	TREM2/SH2B3	2
GO:0070561	vitamin D receptor signaling pathway	2/2053	10/18722	0.30145300854187	0.504946412967957	VDR/TRIM24	2
GO:0071372	cellular response to follicle-stimulating hormone stimulus	2/2053	10/18722	0.30145300854187	0.504946412967957	NOTCH1/GCLM	2
GO:0071421	manganese ion transmembrane transport	2/2053	10/18722	0.30145300854187	0.504946412967957	SLC11A1/TRPM2	2
GO:0072124	regulation of glomerular mesangial cell proliferation	2/2053	10/18722	0.30145300854187	0.504946412967957	BMP7/IL6R	2
GO:0072378	blood coagulation, fibrin clot formation	2/2053	10/18722	0.30145300854187	0.504946412967957	FBLN1/FN1	2
GO:0098903	regulation of membrane repolarization during action potential	2/2053	10/18722	0.30145300854187	0.504946412967957	FLNA/KCNE3	2
GO:0098917	retrograde trans-synaptic signaling	2/2053	10/18722	0.30145300854187	0.504946412967957	DAG1/FABP5	2
GO:1900246	positive regulation of RIG-I signaling pathway	2/2053	10/18722	0.30145300854187	0.504946412967957	OASL/USP15	2
GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	2/2053	10/18722	0.30145300854187	0.504946412967957	NCL/PWP1	2
GO:1902023	L-arginine transport	2/2053	10/18722	0.30145300854187	0.504946412967957	SLC11A1/SLC38A9	2
GO:1904668	positive regulation of ubiquitin protein ligase activity	2/2053	10/18722	0.30145300854187	0.504946412967957	UBE2C/UBE2S	2
GO:1905651	regulation of artery morphogenesis	2/2053	10/18722	0.30145300854187	0.504946412967957	NOTCH1/MDK	2
GO:1905809	negative regulation of synapse organization	2/2053	10/18722	0.30145300854187	0.504946412967957	TLR2/PTN	2
GO:1990535	neuron projection maintenance	2/2053	10/18722	0.30145300854187	0.504946412967957	APP/INSR	2
GO:2000169	regulation of peptidyl-cysteine S-nitrosylation	2/2053	10/18722	0.30145300854187	0.504946412967957	TXN/DMD	2
GO:2000288	positive regulation of myoblast proliferation	2/2053	10/18722	0.30145300854187	0.504946412967957	MALAT1/MEIS2	2
GO:2000434	regulation of protein neddylation	2/2053	10/18722	0.30145300854187	0.504946412967957	RPL5/EPAS1	2
GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	2/2053	10/18722	0.30145300854187	0.504946412967957	WAS/WASF2	2
GO:2001223	negative regulation of neuron migration	2/2053	10/18722	0.30145300854187	0.504946412967957	ADGRG1/STAT3	2
GO:2001225	regulation of chloride transport	2/2053	10/18722	0.30145300854187	0.504946412967957	PTAFR/GABRE	2
GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	2/2053	10/18722	0.30145300854187	0.504946412967957	LGALS9/JAK2	2
GO:0034249	negative regulation of cellular amide metabolic process	33/2053	273/18722	0.302030103526112	0.505771873055169	ZFP36/ZFP36L2/SORL1/TYMS/RPS3/PABPC1/RARA/CALR/ZFP36L1/DHFR/HNRNPR/ORMDL1/BTG2/IGF2BP3/EXOSC8/RPL13A/SPHK1/STAT3/HNRNPD/KHSRP/TPR/EIF2AK4/NCL/RGS2/EIF2AK1/AGO2/SHMT1/MALSU1/TIA1/PURA/EIF4G1/YBX1/GAPDH	33
GO:0051453	regulation of intracellular pH	10/2053	75/18722	0.305279739571691	0.511070992586536	SLC11A1/LRRK2/GRN/HVCN1/PPT1/CHP1/DMXL2/SLC9A1/TCIRG1/ATP6V0E1	10
GO:0019083	viral transcription	7/2053	50/18722	0.306092157379689	0.511859794949312	CCL3/ZFP36/CCL4/IFITM3/NUCKS1/PSMC3/JUN	7
GO:0030490	maturation of SSU-rRNA	7/2053	50/18722	0.306092157379689	0.511859794949312	RPS21/RPS16/RPS14/RPS19/RPS8/SNU13/BMS1	7
GO:0043268	positive regulation of potassium ion transport	7/2053	50/18722	0.306092157379689	0.511859794949312	FLNA/TREM2/KCNQ1/KCNMB1/KCNN4/DLG1/AKAP9	7
GO:0070231	T cell apoptotic process	7/2053	50/18722	0.306092157379689	0.511859794949312	TSC22D3/LGALS9/LGALS3/ADAM8/RPS6/EFNA1/GLI3	7
GO:0043266	regulation of potassium ion transport	14/2053	109/18722	0.306398762107782	0.512229749971216	FLNA/ITGB1/KCNAB2/TREM2/KCNQ1/PTK2B/KCNMB1/KCNE3/ANK3/CD63/KCNN4/YWHAE/DLG1/AKAP9	14
GO:0021915	neural tube development	19/2053	152/18722	0.307449706656926	0.513843520875085	TGFB1/SPINT1/SPINT2/LRP2/VASP/RPS7/RARA/BMP7/NOTCH1/LMO4/ZFP36L1/SOX4/FOLR1/KIF20B/PFN1/LUZP1/GLI3/STK4/COBL	19
GO:0042157	lipoprotein metabolic process	17/2053	135/18722	0.309816067395975	0.517605546389748	OLR1/CTSD/GLUL/APOL6/DBI/NOTUM/ZDHHC12/PPT1/GPAA1/APOC1/PGAP2/APOL3/ITGAV/SVIP/NMT1/DPM2/WIPI2	17
GO:0000266	mitochondrial fission	6/2053	42/18722	0.310822130607044	0.517605546389748	LRRK2/STAT2/INF2/FIS1/BNIP3/PPARG	6
GO:0000413	protein peptidyl-prolyl isomerization	6/2053	42/18722	0.310822130607044	0.517605546389748	PPIA/PPIB/PPIC/FKBP5/FKBP3/FKBP1A	6
GO:0007520	myoblast fusion	6/2053	42/18722	0.310822130607044	0.517605546389748	CD53/CD9/PLEKHO1/CXCL10/ERVW-1/MAPK14	6
GO:0009154	purine ribonucleotide catabolic process	6/2053	42/18722	0.310822130607044	0.517605546389748	HINT1/PDE4A/NUDT8/PNP/NUDT4/AMPD3	6
GO:0010677	negative regulation of cellular carbohydrate metabolic process	6/2053	42/18722	0.310822130607044	0.517605546389748	PLEK/FBP1/PGP/DDIT4/STAT3/MIDN	6
GO:0021879	forebrain neuron differentiation	6/2053	42/18722	0.310822130607044	0.517605546389748	B2M/NRP2/UBB/UQCRQ/NRP1/ZSWIM6	6
GO:0030574	collagen catabolic process	6/2053	42/18722	0.310822130607044	0.517605546389748	CTSS/CST3/CTSB/CTSL/ITGB1/MMP15	6
GO:0030808	regulation of nucleotide biosynthetic process	6/2053	42/18722	0.310822130607044	0.517605546389748	TMSB4X/PARP1/TREM2/PDK4/STAT3/VCP	6
GO:0032467	positive regulation of cytokinesis	6/2053	42/18722	0.310822130607044	0.517605546389748	CDC6/RHOA/KIF23/KIF20B/ECT2/AURKB	6
GO:0045773	positive regulation of axon extension	6/2053	42/18722	0.310822130607044	0.517605546389748	FN1/VEGFA/TRPV2/NRP1/GOLGA4/TWF2	6
GO:0051452	intracellular pH reduction	6/2053	42/18722	0.310822130607044	0.517605546389748	SLC11A1/GRN/PPT1/DMXL2/TCIRG1/ATP6V0E1	6
GO:1904037	positive regulation of epithelial cell apoptotic process	6/2053	42/18722	0.310822130607044	0.517605546389748	JAK2/ITGA4/ARRB2/RGCC/BAD/TIA1	6
GO:0043967	histone H4 acetylation	9/2053	67/18722	0.311487817738697	0.518324523909321	SPI1/MORF4L2/BRCA1/HAT1/BRCA2/USP22/PHF20/YEATS4/ACTL6A	9
GO:0072665	protein localization to vacuole	9/2053	67/18722	0.311487817738697	0.518324523909321	LAPTM5/SORL1/TNFAIP3/GBP1/HSPA8/LAMTOR4/MFSD1/VPS13C/VPS25	9
GO:0044262	cellular carbohydrate metabolic process	34/2053	283/18722	0.311513038869502	0.518324523909321	PLEK/HMGB1/ISYNA1/FBP1/PHLDA2/AOAH/PGP/PTAFR/AGL/HK3/PTK2B/PDK4/HK2/DDIT4/IDH2/SLC35B4/PMAIP1/AKR1B1/DDB1/STAT3/IL6ST/IMPA2/IDH1/UGP2/BAD/GAA/MIDN/C1QTNF1/LCMT1/INSR/PHKB/GK/ENOSF1/PRKAG2	34
GO:0030203	glycosaminoglycan metabolic process	15/2053	118/18722	0.311761287842712	0.518593769630239	CD44/TGFB1/ITIH5/IL1B/CHPF/HS3ST1/FUCA1/CHST15/IDS/CHST14/DSE/FOXC1/B3GAT3/HEXB/HS6ST2	15
GO:0032370	positive regulation of lipid transport	11/2053	84/18722	0.313219582819362	0.519751363890344	SPP1/RETN/IL1B/NFKBIA/TREM2/DBI/TRIAP1/PTGES/C1QTNF1/LDLRAP1/PPARG	11
GO:0042310	vasoconstriction	11/2053	84/18722	0.313219582819362	0.519751363890344	SLC8A1/EGFR/DOCK4/TBXAS1/ATP2B1/ICAM1/GJA1/HRH2/GJA5/SLC6A4/RHOA	11
GO:0007612	learning	18/2053	144/18722	0.313995364866613	0.519751363890344	TLR2/FOS/APP/ITGB1/COMT/PPT1/BTG2/TPBG/CNTNAP2/ACTR2/VDAC1/NRGN/EIF2AK4/JUN/PAK6/INSR/PTN/MEIS2	18
GO:0006356	regulation of transcription by RNA polymerase I	5/2053	34/18722	0.314810064331418	0.519751363890344	FLNA/POLR2L/NCL/POLR2K/PWP1	5
GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	5/2053	34/18722	0.314810064331418	0.519751363890344	CCL3/SLC8A1/CAMK2D/CALM2/DMD	5
GO:0019320	hexose catabolic process	5/2053	34/18722	0.314810064331418	0.519751363890344	HK3/HK2/LRP5/FUT8/BAD	5
GO:0035590	purinergic nucleotide receptor signaling pathway	5/2053	34/18722	0.314810064331418	0.519751363890344	PTAFR/P2RY13/P2RX7/GNAI2/P2RY11	5
GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	5/2053	34/18722	0.314810064331418	0.519751363890344	C3AR1/GPR65/LPAR6/TGM2/GNA15	5
GO:0070232	regulation of T cell apoptotic process	5/2053	34/18722	0.314810064331418	0.519751363890344	TSC22D3/LGALS9/LGALS3/ADAM8/EFNA1	5
GO:1904893	negative regulation of receptor signaling pathway via STAT	5/2053	34/18722	0.314810064331418	0.519751363890344	SOCS3/SH2B3/SUZ12/PARP14/PPARG	5
GO:0001946	lymphangiogenesis	3/2053	18/18722	0.315489077881439	0.519751363890344	VASH1/PTPN14/FOXC1	3
GO:0003128	heart field specification	3/2053	18/18722	0.315489077881439	0.519751363890344	MEF2C/LRP2/ISL1	3
GO:0006103	2-oxoglutarate metabolic process	3/2053	18/18722	0.315489077881439	0.519751363890344	IDH2/IDH1/MRPS36	3
GO:0006957	complement activation, alternative pathway	3/2053	18/18722	0.315489077881439	0.519751363890344	CFD/CFP/C3	3
GO:0030206	chondroitin sulfate biosynthetic process	3/2053	18/18722	0.315489077881439	0.519751363890344	CHPF/CHST15/DSE	3
GO:0030728	ovulation	3/2053	18/18722	0.315489077881439	0.519751363890344	ADAMTS1/HPGD/RGS2	3
GO:0032634	interleukin-5 production	3/2053	18/18722	0.315489077881439	0.519751363890344	LILRB4/RARA/GATA3	3
GO:0032674	regulation of interleukin-5 production	3/2053	18/18722	0.315489077881439	0.519751363890344	LILRB4/RARA/GATA3	3
GO:0032785	negative regulation of DNA-templated transcription, elongation	3/2053	18/18722	0.315489077881439	0.519751363890344	EZH2/RNF8/NELFCD	3
GO:0033189	response to vitamin A	3/2053	18/18722	0.315489077881439	0.519751363890344	TYMS/RARA/HAMP	3
GO:0042790	nucleolar large rRNA transcription by RNA polymerase I	3/2053	18/18722	0.315489077881439	0.519751363890344	TCOF1/NCL/PWP1	3
GO:0048268	clathrin coat assembly	3/2053	18/18722	0.315489077881439	0.519751363890344	NSG1/CLTA/PICALM	3
GO:0048486	parasympathetic nervous system development	3/2053	18/18722	0.315489077881439	0.519751363890344	NRP2/TFAP2A/NRP1	3
GO:0051447	negative regulation of meiotic cell cycle	3/2053	18/18722	0.315489077881439	0.519751363890344	DUSP1/FBXO5/TTK	3
GO:0060546	negative regulation of necroptotic process	3/2053	18/18722	0.315489077881439	0.519751363890344	BIRC3/SLC25A4/ARHGEF2	3
GO:0061687	detoxification of inorganic compound	3/2053	18/18722	0.315489077881439	0.519751363890344	MT1X/MT2A/PARK7	3
GO:0071071	regulation of phospholipid biosynthetic process	3/2053	18/18722	0.315489077881439	0.519751363890344	CHP1/IDH1/PDGFA	3
GO:0072234	metanephric nephron tubule development	3/2053	18/18722	0.315489077881439	0.519751363890344	STAT1/LGR4/YAP1	3
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	3/2053	18/18722	0.315489077881439	0.519751363890344	VEGFA/MAGED1/LGR4	3
GO:0097709	connective tissue replacement	3/2053	18/18722	0.315489077881439	0.519751363890344	TIMP1/TGFB1/RUNX1	3
GO:1900424	regulation of defense response to bacterium	3/2053	18/18722	0.315489077881439	0.519751363890344	CYBA/HAVCR2/GRN	3
GO:1902074	response to salt	3/2053	18/18722	0.315489077881439	0.519751363890344	HSPA5/HNRNPA1/HNRNPD	3
GO:1905820	positive regulation of chromosome separation	3/2053	18/18722	0.315489077881439	0.519751363890344	ANAPC11/CDT1/PLSCR1	3
GO:2000136	regulation of cell proliferation involved in heart morphogenesis	3/2053	18/18722	0.315489077881439	0.519751363890344	NOTCH1/ISL1/TBX3	3
GO:2000641	regulation of early endosome to late endosome transport	3/2053	18/18722	0.315489077881439	0.519751363890344	MSN/RDX/EZR	3
GO:0048565	digestive tract development	16/2053	127/18722	0.316543438218741	0.521202627063356	EGFR/TYMS/TNF/NOTCH1/KCNQ1/CXCL8/IL6ST/AHI1/ASS1/LGR4/YAP1/KLF5/CDKN1A/GLI3/ID2/COBL	16
GO:0001963	synaptic transmission, dopaminergic	4/2053	26/18722	0.317151798568052	0.521202627063356	ARRB2/PNKD/SLC6A4/PARK7	4
GO:0006027	glycosaminoglycan catabolic process	4/2053	26/18722	0.317151798568052	0.521202627063356	CD44/TGFB1/FUCA1/IDS	4
GO:0009435	NAD biosynthetic process	4/2053	26/18722	0.317151798568052	0.521202627063356	NAMPT/KYNU/QPRT/PARP9	4
GO:0014829	vascular associated smooth muscle contraction	4/2053	26/18722	0.317151798568052	0.521202627063356	SLC8A1/DOCK4/ATP2B1/RHOA	4
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	4/2053	26/18722	0.317151798568052	0.521202627063356	HLA-F/HLA-E/CADM1/VAV1	4
GO:0048843	negative regulation of axon extension involved in axon guidance	4/2053	26/18722	0.317151798568052	0.521202627063356	SEMA4A/SEMA6A/NRP1/SEMA6D	4
GO:0060037	pharyngeal system development	4/2053	26/18722	0.317151798568052	0.521202627063356	BMP7/ISL1/GATA3/FOLR1	4
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	4/2053	26/18722	0.317151798568052	0.521202627063356	CAMK2D/CALM2/DMD/FKBP1A	4
GO:0016054	organic acid catabolic process	29/2053	240/18722	0.317564899723643	0.521738608527344	SDS/GCSH/KYNU/SLC27A2/GLUL/ECI1/QPRT/IL4I1/ECHS1/DDAH2/ACADVL/GLDC/SDSL/ECHDC2/ETFB/NUDT8/CDO1/HADH/OAT/ETFA/ACAT2/ABHD2/QDPR/ECI2/SHMT1/SLC25A17/ECH1/PPAT/ENOSF1	29
GO:0044242	cellular lipid catabolic process	26/2053	214/18722	0.319314022979475	0.524468693642718	SORL1/AOAH/SLC27A2/GPCPD1/ECI1/ECHS1/PLA2G7/ACADVL/PPT1/ECHDC2/ETFB/NUDT8/APOC1/SPHK1/FUCA1/HADH/PRDX6/ETFA/ACAT2/ABHD2/IDH1/ECI2/MGLL/SLC25A17/HEXB/ECH1	26
GO:0001937	negative regulation of endothelial cell proliferation	10/2053	76/18722	0.320099152436781	0.525470564875701	MEF2C/ALOX5/TNF/STAT1/VASH1/NR2F2/FLT1/GJA1/RGCC/PPARG	10
GO:0140115	export across plasma membrane	10/2053	76/18722	0.320099152436781	0.525470564875701	SLC8A1/SLC40A1/ATP2B1/KCNQ1/GJA1/KCNE3/CALM2/YWHAE/SLC9A1/DLG1	10
GO:0010656	negative regulation of muscle cell apoptotic process	7/2053	51/18722	0.324390367953609	0.532223737413633	JAK2/HMOX1/ARRB2/DNMT1/BMP7/PTK2B/MDK	7
GO:0045668	negative regulation of osteoblast differentiation	7/2053	51/18722	0.324390367953609	0.532223737413633	TNF/NOTCH1/CRIM1/LRP5/ID3/CDK6/PPARG	7
GO:0010522	regulation of calcium ion transport into cytosol	13/2053	102/18722	0.325872154189303	0.534362646935179	CORO1A/CYBA/LYN/SLC8A1/CXCL10/PTPN6/PTK2B/P2RX7/CAMK2D/CALM2/DMD/FKBP1A/UBASH3B	13
GO:0014897	striated muscle hypertrophy	13/2053	102/18722	0.325872154189303	0.534362646935179	TNFRSF1B/PARP1/MEF2A/NOTCH1/HAMP/EZH2/CAMK2D/HDAC2/IL6ST/PARP2/RGS2/SLC9A1/LMNA	13
GO:0051926	negative regulation of calcium ion transport	9/2053	68/18722	0.327309986211567	0.536427183083693	LILRB2/LILRB1/ICAM1/CD33/CALM2/C4orf3/VDAC1/YWHAE/PACSIN3	9
GO:1900046	regulation of hemostasis	9/2053	68/18722	0.327309986211567	0.536427183083693	CD9/PRDX2/CD36/HPSE/SH2B3/C1QTNF1/UBASH3B/PDGFA/SERPING1	9
GO:0007605	sensory perception of sound	19/2053	154/18722	0.32823104799911	0.537789811030765	GPX1/MBP/LRP2/SOD1/ALDH7A1/KCNQ1/ICAM1/BIRC5/TIMM13/NDUFB9/TFAP2A/ATP6V1B1/USP53/EPS8L2/TBL1X/HEXB/TRIOBP/SLC1A3/MYO7A	19
GO:0001504	neurotransmitter uptake	6/2053	43/18722	0.330960430904565	0.540711075046291	SLC38A1/ITGB1/SLC29A1/SLC6A4/PARK7/SLC1A3	6
GO:0001709	cell fate determination	6/2053	43/18722	0.330960430904565	0.540711075046291	MEF2C/KLF4/MCL1/ISL1/NOTCH2/GATA3	6
GO:0010171	body morphogenesis	6/2053	43/18722	0.330960430904565	0.540711075046291	DAG1/RRAS/ARID5B/PLEKHA1/CRISPLD1/GPC3	6
GO:0014014	negative regulation of gliogenesis	6/2053	43/18722	0.330960430904565	0.540711075046291	TSPO/NOTCH1/TREM2/IDH2/ASCL2/PTN	6
GO:0140353	lipid export from cell	6/2053	43/18722	0.330960430904565	0.540711075046291	SPP1/RETN/IL1B/KCNQ1/PTGES/C1QTNF1	6
GO:1901381	positive regulation of potassium ion transmembrane transport	6/2053	43/18722	0.330960430904565	0.540711075046291	FLNA/TREM2/KCNQ1/KCNMB1/KCNN4/AKAP9	6
GO:1903793	positive regulation of anion transport	6/2053	43/18722	0.330960430904565	0.540711075046291	TCAF1/IL1B/PTAFR/CEBPB/ITGB1/PTGES	6
GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	6/2053	43/18722	0.330960430904565	0.540711075046291	PRDX2/TNF/IL1B/IFI6/MCL1/HSPA1A	6
GO:0001938	positive regulation of endothelial cell proliferation	14/2053	111/18722	0.331005296440838	0.540711075046291	CYBA/HMGB1/VEGFA/HMGB2/ITGA4/HMOX1/NRP2/TNFSF12/NR4A1/STAT5A/NRP1/STAT3/MYDGF/MDK	14
GO:0071867	response to monoamine	14/2053	111/18722	0.331005296440838	0.540711075046291	FLNA/LRRK2/APP/GNAS/ARRB2/TGM2/NSG1/KCNQ1/GNA15/ID1/HRH2/HDAC2/GNA11/SLC9A1	14
GO:0071869	response to catecholamine	14/2053	111/18722	0.331005296440838	0.540711075046291	FLNA/LRRK2/APP/GNAS/ARRB2/TGM2/NSG1/KCNQ1/GNA15/ID1/HRH2/HDAC2/GNA11/SLC9A1	14
GO:0055123	digestive system development	17/2053	137/18722	0.331958028237256	0.542119806593232	EGFR/TYMS/TNF/WLS/NOTCH1/KCNQ1/CXCL8/IL6ST/AHI1/ASS1/LGR4/YAP1/KLF5/CDKN1A/GLI3/ID2/COBL	17
GO:1903035	negative regulation of response to wounding	12/2053	94/18722	0.33349591537107	0.544483127136441	CD9/SPP1/ALOX5/TNF/SIGLEC10/SH2B3/GJA1/C1QTNF1/MDK/UBASH3B/PDGFA/SERPING1	12
GO:0048736	appendage development	21/2053	172/18722	0.334375322274104	0.545473608930023	FBN2/ITGA6/RARA/BMP7/NOTCH1/ITGB4/NR2F2/SLC39A1/TFAP2A/FRAS1/NOTCH2/SOX4/HDAC2/PBX1/LRP5/FERMT2/MBNL1/GLI3/TBX3/ZNRF3/GPC3	21
GO:0060173	limb development	21/2053	172/18722	0.334375322274104	0.545473608930023	FBN2/ITGA6/RARA/BMP7/NOTCH1/ITGB4/NR2F2/SLC39A1/TFAP2A/FRAS1/NOTCH2/SOX4/HDAC2/PBX1/LRP5/FERMT2/MBNL1/GLI3/TBX3/ZNRF3/GPC3	21
GO:1990138	neuron projection extension	21/2053	172/18722	0.334375322274104	0.545473608930023	CXCR4/FN1/VEGFA/ITGA4/NRP2/HSP90AA1/HSP90AB1/ITGB1/ALCAM/SEMA4A/ARHGAP4/TRPV2/SEMA6A/ITSN2/NRP1/GOLGA4/TWF2/SEMA6D/EIF2AK4/VCL/PAK6	21
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	8/2053	60/18722	0.334884496671376	0.545620401095321	CELF2/SRSF2/MBNL3/HNRNPA1/MAGOH/MBNL1/RBMX/TRA2B	8
GO:0006893	Golgi to plasma membrane transport	8/2053	60/18722	0.334884496671376	0.545620401095321	VAMP5/KRT18/CSK/GOLGA4/ANK3/SPTBN1/GOPC/COMMD1	8
GO:0010675	regulation of cellular carbohydrate metabolic process	18/2053	146/18722	0.33552376568478	0.545620401095321	PLEK/HMGB1/FBP1/PHLDA2/PGP/PTAFR/PTK2B/PDK4/DDIT4/SLC35B4/PMAIP1/DDB1/STAT3/BAD/MIDN/C1QTNF1/LCMT1/INSR	18
GO:0030323	respiratory tube development	22/2053	181/18722	0.337073499266281	0.545620401095321	HMGB1/EGFR/VEGFA/KLF2/TNF/CTSH/CTSZ/DAG1/MME/LAMA5/NOTCH1/HSPB11/EPAS1/DLG5/LIPA/YAP1/GLI3/PTN/DPPA4/PDGFA/ASXL1/GPC3	22
GO:0006739	NADP metabolic process	5/2053	35/18722	0.337380999669652	0.545620401095321	KCNAB2/IDH2/DCXR/RPIA/IDH1	5
GO:0015695	organic cation transport	5/2053	35/18722	0.337380999669652	0.545620401095321	SLC29A1/SLC44A1/SLC25A17/SLC44A2/SLC19A3	5
GO:0018149	peptide cross-linking	5/2053	35/18722	0.337380999669652	0.545620401095321	FN1/DSP/TGM2/CSTA/KRT10	5
GO:0034331	cell junction maintenance	5/2053	35/18722	0.337380999669652	0.545620401095321	CSF1R/TJP1/FERMT2/CHCHD10/DLG1	5
GO:0071108	protein K48-linked deubiquitination	5/2053	35/18722	0.337380999669652	0.545620401095321	TNFAIP3/USP15/USP27X/PARK7/DESI2	5
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	5/2053	35/18722	0.337380999669652	0.545620401095321	VEGFA/HMOX1/NRP1/CIB1/PLK2	5
GO:1903514	release of sequestered calcium ion into cytosol by endoplasmic reticulum	5/2053	35/18722	0.337380999669652	0.545620401095321	CCL3/SLC8A1/CAMK2D/CALM2/DMD	5
GO:0019233	sensory perception of pain	13/2053	103/18722	0.33882295532113	0.545620401095321	CXCR4/CCL3/PTAFR/CCR2/ARRB2/NR2F6/MME/COMT/P2RX7/FABP5/SLC9A1/PTGES/MGLL	13
GO:0008037	cell recognition	27/2053	225/18722	0.339034364513367	0.545620401095321	CXCR4/FCN1/MSN/VCAN/PECAM1/CLEC7A/CD9/HAVCR2/COLEC12/CD36/APP/DOCK2/CADM1/BSG/LGALS3/TREM2/SPESP1/CNTNAP2/ALDOA/NRP1/TCP1/FOLR1/CCT2/DLG1/PALLD/CCT4/CCT8	27
GO:0006334	nucleosome assembly	16/2053	129/18722	0.339563857260059	0.545620401095321	NASP/HMGB2/DNAJC9/CENPW/NPM1/ASF1B/SET/NAP1L1/RBBP4/MCM2/HAT1/ITGB3BP/CHAF1A/MIS18A/NAP1L4/SMARCA5	16
GO:0051496	positive regulation of stress fiber assembly	7/2053	52/18722	0.342855837624772	0.545620401095321	GPR65/CCDC88A/S100A10/NRP1/RHOA/RGCC/FERMT2	7
GO:0000469	cleavage involved in rRNA processing	4/2053	27/18722	0.343166545349028	0.545620401095321	RPS21/EXOSC8/NHP2/BMS1	4
GO:0001835	blastocyst hatching	4/2053	27/18722	0.343166545349028	0.545620401095321	LPAR6/ASF1B/CMTM3/RBBP8	4
GO:0003171	atrioventricular valve development	4/2053	27/18722	0.343166545349028	0.545620401095321	NOTCH1/GJA5/SOX4/EFNA1	4
GO:0003272	endocardial cushion formation	4/2053	27/18722	0.343166545349028	0.545620401095321	BMP7/ENG/NOTCH1/TBX3	4
GO:0033561	regulation of water loss via skin	4/2053	27/18722	0.343166545349028	0.545620401095321	STMN1/MET/CLDN4/LSR	4
GO:0035188	hatching	4/2053	27/18722	0.343166545349028	0.545620401095321	LPAR6/ASF1B/CMTM3/RBBP8	4
GO:0048520	positive regulation of behavior	4/2053	27/18722	0.343166545349028	0.545620401095321	MEF2C/GJA1/HDAC2/CFAP20	4
GO:0071684	organism emergence from protective structure	4/2053	27/18722	0.343166545349028	0.545620401095321	LPAR6/ASF1B/CMTM3/RBBP8	4
GO:0099625	ventricular cardiac muscle cell membrane repolarization	4/2053	27/18722	0.343166545349028	0.545620401095321	KCNQ1/KCNE3/GJA5/AKAP9	4
GO:1902914	regulation of protein polyubiquitination	4/2053	27/18722	0.343166545349028	0.545620401095321	PPIA/UBE2D1/SKP2/GABARAP	4
GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation	2/2053	11/18722	0.343740852690052	0.545620401095321	TSEN34/DDX1	2
GO:0001765	membrane raft assembly	2/2053	11/18722	0.343740852690052	0.545620401095321	EMP2/S100A10	2
GO:0001787	natural killer cell proliferation	2/2053	11/18722	0.343740852690052	0.545620401095321	HLA-E/IL18	2
GO:0001867	complement activation, lectin pathway	2/2053	11/18722	0.343740852690052	0.545620401095321	FCN1/SERPING1	2
GO:0002725	negative regulation of T cell cytokine production	2/2053	11/18722	0.343740852690052	0.545620401095321	HLA-F/LILRB4	2
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	2/2053	11/18722	0.343740852690052	0.545620401095321	CD46/PTPN6	2
GO:0003157	endocardium development	2/2053	11/18722	0.343740852690052	0.545620401095321	NOTCH1/STK4	2
GO:0003263	cardioblast proliferation	2/2053	11/18722	0.343740852690052	0.545620401095321	NOTCH1/ISL1	2
GO:0003264	regulation of cardioblast proliferation	2/2053	11/18722	0.343740852690052	0.545620401095321	NOTCH1/ISL1	2
GO:0006020	inositol metabolic process	2/2053	11/18722	0.343740852690052	0.545620401095321	ISYNA1/IMPA2	2
GO:0006527	arginine catabolic process	2/2053	11/18722	0.343740852690052	0.545620401095321	DDAH2/OAT	2
GO:0006568	tryptophan metabolic process	2/2053	11/18722	0.343740852690052	0.545620401095321	KYNU/IL4I1	2
GO:0007042	lysosomal lumen acidification	2/2053	11/18722	0.343740852690052	0.545620401095321	GRN/PPT1	2
GO:0007144	female meiosis I	2/2053	11/18722	0.343740852690052	0.545620401095321	UBB/FBXO5	2
GO:0008611	ether lipid biosynthetic process	2/2053	11/18722	0.343740852690052	0.545620401095321	LPCAT2/CHPT1	2
GO:0010887	negative regulation of cholesterol storage	2/2053	11/18722	0.343740852690052	0.545620401095321	TREM2/PPARG	2
GO:0010986	positive regulation of lipoprotein particle clearance	2/2053	11/18722	0.343740852690052	0.545620401095321	TREM2/LDLRAP1	2
GO:0018026	peptidyl-lysine monomethylation	2/2053	11/18722	0.343740852690052	0.545620401095321	SMYD2/KMT5A	2
GO:0021561	facial nerve development	2/2053	11/18722	0.343740852690052	0.545620401095321	NRP2/NRP1	2
GO:0021604	cranial nerve structural organization	2/2053	11/18722	0.343740852690052	0.545620401095321	NRP2/NRP1	2
GO:0021610	facial nerve morphogenesis	2/2053	11/18722	0.343740852690052	0.545620401095321	NRP2/NRP1	2
GO:0030432	peristalsis	2/2053	11/18722	0.343740852690052	0.545620401095321	DLG1/TBX3	2
GO:0031652	positive regulation of heat generation	2/2053	11/18722	0.343740852690052	0.545620401095321	TNF/IL1B	2
GO:0032308	positive regulation of prostaglandin secretion	2/2053	11/18722	0.343740852690052	0.545620401095321	IL1B/PTGES	2
GO:0032957	inositol trisphosphate metabolic process	2/2053	11/18722	0.343740852690052	0.545620401095321	PTAFR/PTK2B	2
GO:0033483	gas homeostasis	2/2053	11/18722	0.343740852690052	0.545620401095321	SOD2/GSTP1	2
GO:0033632	regulation of cell-cell adhesion mediated by integrin	2/2053	11/18722	0.343740852690052	0.545620401095321	FERMT3/DPP4	2
GO:0034163	regulation of toll-like receptor 9 signaling pathway	2/2053	11/18722	0.343740852690052	0.545620401095321	HMGB1/RSAD2	2
GO:0039530	MDA-5 signaling pathway	2/2053	11/18722	0.343740852690052	0.545620401095321	IRF7/C1QBP	2
GO:0042447	hormone catabolic process	2/2053	11/18722	0.343740852690052	0.545620401095321	SPP1/HSD17B11	2
GO:0043589	skin morphogenesis	2/2053	11/18722	0.343740852690052	0.545620401095321	ITGA6/ITGB4	2
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	2/2053	11/18722	0.343740852690052	0.545620401095321	HMOX1/EPAS1	2
GO:0044068	modulation by symbiont of host cellular process	2/2053	11/18722	0.343740852690052	0.545620401095321	CD4/PHB2	2
GO:0045793	positive regulation of cell size	2/2053	11/18722	0.343740852690052	0.545620401095321	HSP90AB1/CDK4	2
GO:0046501	protoporphyrinogen IX metabolic process	2/2053	11/18722	0.343740852690052	0.545620401095321	EIF2AK1/ALAD	2
GO:0046504	glycerol ether biosynthetic process	2/2053	11/18722	0.343740852690052	0.545620401095321	LPCAT2/CHPT1	2
GO:0046710	GDP metabolic process	2/2053	11/18722	0.343740852690052	0.545620401095321	DLG1/MPP1	2
GO:0046929	negative regulation of neurotransmitter secretion	2/2053	11/18722	0.343740852690052	0.545620401095321	PNKD/RAP1A	2
GO:0048096	chromatin-mediated maintenance of transcription	2/2053	11/18722	0.343740852690052	0.545620401095321	CDCA4/CHEK1	2
GO:0048103	somatic stem cell division	2/2053	11/18722	0.343740852690052	0.545620401095321	ZFP36L2/NOTCH1	2
GO:0051081	nuclear membrane disassembly	2/2053	11/18722	0.343740852690052	0.545620401095321	VRK1/PRKCB	2
GO:0051132	NK T cell activation	2/2053	11/18722	0.343740852690052	0.545620401095321	CD300A/IL18	2
GO:0051573	negative regulation of histone H3-K9 methylation	2/2053	11/18722	0.343740852690052	0.545620401095321	DNMT1/BRCA1	2
GO:0051798	positive regulation of hair follicle development	2/2053	11/18722	0.343740852690052	0.545620401095321	TNF/HPSE	2
GO:0060312	regulation of blood vessel remodeling	2/2053	11/18722	0.343740852690052	0.545620401095321	TGFB1/CST3	2
GO:0060379	cardiac muscle cell myoblast differentiation	2/2053	11/18722	0.343740852690052	0.545620401095321	NOTCH1/ISL1	2
GO:0060742	epithelial cell differentiation involved in prostate gland development	2/2053	11/18722	0.343740852690052	0.545620401095321	PSAP/NOTCH1	2
GO:0060767	epithelial cell proliferation involved in prostate gland development	2/2053	11/18722	0.343740852690052	0.545620401095321	SERPINF1/NOTCH1	2
GO:0060837	blood vessel endothelial cell differentiation	2/2053	11/18722	0.343740852690052	0.545620401095321	NOTCH1/NRP1	2
GO:0061029	eyelid development in camera-type eye	2/2053	11/18722	0.343740852690052	0.545620401095321	TFAP2A/HDAC2	2
GO:0070243	regulation of thymocyte apoptotic process	2/2053	11/18722	0.343740852690052	0.545620401095321	ADAM8/EFNA1	2
GO:0070778	L-aspartate transmembrane transport	2/2053	11/18722	0.343740852690052	0.545620401095321	SLC1A5/SLC1A3	2
GO:0070933	histone H4 deacetylation	2/2053	11/18722	0.343740852690052	0.545620401095321	HDAC2/RCOR1	2
GO:0070944	neutrophil-mediated killing of bacterium	2/2053	11/18722	0.343740852690052	0.545620401095321	TREM1/MYD88	2
GO:0071492	cellular response to UV-A	2/2053	11/18722	0.343740852690052	0.545620401095321	TIMP1/MME	2
GO:0072110	glomerular mesangial cell proliferation	2/2053	11/18722	0.343740852690052	0.545620401095321	BMP7/IL6R	2
GO:0072205	metanephric collecting duct development	2/2053	11/18722	0.343740852690052	0.545620401095321	AKR1B1/DLG5	2
GO:0075522	IRES-dependent viral translational initiation	2/2053	11/18722	0.343740852690052	0.545620401095321	DENR/EIF3A	2
GO:0075733	intracellular transport of virus	2/2053	11/18722	0.343740852690052	0.545620401095321	BST2/DYNLT1	2
GO:0090084	negative regulation of inclusion body assembly	2/2053	11/18722	0.343740852690052	0.545620401095321	SORL1/HSPA1A	2
GO:0090309	positive regulation of DNA methylation-dependent heterochromatin assembly	2/2053	11/18722	0.343740852690052	0.545620401095321	DNMT1/TRIM28	2
GO:0090649	response to oxygen-glucose deprivation	2/2053	11/18722	0.343740852690052	0.545620401095321	NAMPT/BNIP3	2
GO:0097384	cellular lipid biosynthetic process	2/2053	11/18722	0.343740852690052	0.545620401095321	LPCAT2/CHPT1	2
GO:0097396	response to interleukin-17	2/2053	11/18722	0.343740852690052	0.545620401095321	NOTCH1/IL17RA	2
GO:0097398	cellular response to interleukin-17	2/2053	11/18722	0.343740852690052	0.545620401095321	NOTCH1/IL17RA	2
GO:0097400	interleukin-17-mediated signaling pathway	2/2053	11/18722	0.343740852690052	0.545620401095321	NOTCH1/IL17RA	2
GO:0099624	atrial cardiac muscle cell membrane repolarization	2/2053	11/18722	0.343740852690052	0.545620401095321	FLNA/KCNQ1	2
GO:0140042	lipid droplet formation	2/2053	11/18722	0.343740852690052	0.545620401095321	SQLE/CDS1	2
GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	2/2053	11/18722	0.343740852690052	0.545620401095321	CHCHD10/NMT1	2
GO:1901533	negative regulation of hematopoietic progenitor cell differentiation	2/2053	11/18722	0.343740852690052	0.545620401095321	NOTCH1/HSPA9	2
GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction	2/2053	11/18722	0.343740852690052	0.545620401095321	CAMK2D/CALM2	2
GO:1902667	regulation of axon guidance	2/2053	11/18722	0.343740852690052	0.545620401095321	VEGFA/NRP1	2
GO:1903299	regulation of hexokinase activity	2/2053	11/18722	0.343740852690052	0.545620401095321	BAD/MIDN	2
GO:1903423	positive regulation of synaptic vesicle recycling	2/2053	11/18722	0.343740852690052	0.545620401095321	LRRK2/AP2M1	2
GO:1903897	regulation of PERK-mediated unfolded protein response	2/2053	11/18722	0.343740852690052	0.545620401095321	HSPA5/PPP1R15A	2
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	2/2053	11/18722	0.343740852690052	0.545620401095321	TJP1/PTPRU	2
GO:2000480	negative regulation of cAMP-dependent protein kinase activity	2/2053	11/18722	0.343740852690052	0.545620401095321	PKIB/PRKAG2	2
GO:0000729	DNA double-strand break processing	3/2053	19/18722	0.346961060994944	0.547833254202543	BLM/RBBP8/UBE2N	3
GO:0003085	negative regulation of systemic arterial blood pressure	3/2053	19/18722	0.346961060994944	0.547833254202543	SOD2/KCNK6/ADRB1	3
GO:0007039	protein catabolic process in the vacuole	3/2053	19/18722	0.346961060994944	0.547833254202543	LRP2/TPP1/TCIRG1	3
GO:0009081	branched-chain amino acid metabolic process	3/2053	19/18722	0.346961060994944	0.547833254202543	SDS/ECHS1/SDSL	3
GO:0010744	positive regulation of macrophage derived foam cell differentiation	3/2053	19/18722	0.346961060994944	0.547833254202543	MSR1/CD36/IL18	3
GO:0032011	ARF protein signal transduction	3/2053	19/18722	0.346961060994944	0.547833254202543	CYTH4/CYTH1/ARFGEF3	3
GO:0032012	regulation of ARF protein signal transduction	3/2053	19/18722	0.346961060994944	0.547833254202543	CYTH4/CYTH1/ARFGEF3	3
GO:0043652	engulfment of apoptotic cell	3/2053	19/18722	0.346961060994944	0.547833254202543	RAC2/TREM2/RHOG	3
GO:0045618	positive regulation of keratinocyte differentiation	3/2053	19/18722	0.346961060994944	0.547833254202543	NOTCH1/VDR/FOXC1	3
GO:0045821	positive regulation of glycolytic process	3/2053	19/18722	0.346961060994944	0.547833254202543	APP/P2RX7/INSR	3
GO:0048245	eosinophil chemotaxis	3/2053	19/18722	0.346961060994944	0.547833254202543	CCL3/CCL4/LGALS3	3
GO:0050961	detection of temperature stimulus involved in sensory perception	3/2053	19/18722	0.346961060994944	0.547833254202543	CXCR4/ARRB2/NR2F6	3
GO:0061323	cell proliferation involved in heart morphogenesis	3/2053	19/18722	0.346961060994944	0.547833254202543	NOTCH1/ISL1/TBX3	3
GO:0062099	negative regulation of programmed necrotic cell death	3/2053	19/18722	0.346961060994944	0.547833254202543	BIRC3/SLC25A4/ARHGEF2	3
GO:0070262	peptidyl-serine dephosphorylation	3/2053	19/18722	0.346961060994944	0.547833254202543	DUSP1/YWHAE/PPP1R15A	3
GO:0070734	histone H3-K27 methylation	3/2053	19/18722	0.346961060994944	0.547833254202543	EZH2/SUZ12/GATA3	3
GO:0072074	kidney mesenchyme development	3/2053	19/18722	0.346961060994944	0.547833254202543	STAT1/BMP7/BASP1	3
GO:0097623	potassium ion export across plasma membrane	3/2053	19/18722	0.346961060994944	0.547833254202543	KCNQ1/KCNE3/DLG1	3
GO:0098780	response to mitochondrial depolarisation	3/2053	19/18722	0.346961060994944	0.547833254202543	HK2/VPS13C/HUWE1	3
GO:2000369	regulation of clathrin-dependent endocytosis	3/2053	19/18722	0.346961060994944	0.547833254202543	BMP2K/AAK1/DGKD	3
GO:0042752	regulation of circadian rhythm	15/2053	121/18722	0.347572564804371	0.548654403795377	NR2F6/MAGED1/PRKDC/TOP2A/CDK1/EZH2/DDB1/ADRB1/SIAH2/HNRNPD/BHLHE40/GNA11/TIMELESS/ID2/PPARG	15
GO:0001764	neuron migration	19/2053	156/18722	0.349359313166134	0.551329794580959	CXCR4/FLNA/PHACTR1/MEF2C/VEGFA/NR4A2/ADGRG1/NRP2/NR2F2/SEMA6A/DDIT4/ASPM/NRP1/STAT3/GATA3/KIF20B/ARHGEF2/TOP2B/MDK	19
GO:0043537	negative regulation of blood vessel endothelial cell migration	10/2053	78/18722	0.350159519296066	0.552447308907809	TGFB1/MEF2C/HMGB1/KLF4/TNF/VASH1/NOTCH1/RHOA/RGCC/PPARG	10
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	6/2053	44/18722	0.351251200800366	0.553732844141408	MSN/FAT1/RHOA/PARD3/DLG5/DLG1	6
GO:0048066	developmental pigmentation	6/2053	44/18722	0.351251200800366	0.553732844141408	ZEB2/RAB32/MEF2C/CD63/GNA11/GLI3	6
GO:0089718	amino acid import across plasma membrane	6/2053	44/18722	0.351251200800366	0.553732844141408	ITGB1/SLC6A6/SLC1A5/RGS2/SLC3A2/SLC1A3	6
GO:0022600	digestive system process	13/2053	104/18722	0.351875477701583	0.554571280853559	TYMP/SNX10/TLR4/CD36/SGK1/KCNQ1/HAMP/HRH2/VDR/KCNN4/EZR/LIMA1/EPB41	13
GO:0006900	vesicle budding from membrane	8/2053	61/18722	0.352034992343406	0.554648686930482	TMED9/S100A10/FNBP1L/CHMP4C/PICALM/AP2M1/TFG/SEC31A	8
GO:0010876	lipid localization	52/2053	448/18722	0.352109474753034	0.554648686930482	TSPO/MSR1/NPC2/PSAP/SPP1/RETN/TNF/AQP9/IL1B/CD36/SLC2A1/SLC27A2/C3/APOBR/APOL6/NFKBIA/SYK/MEST/TREM2/DBI/KCNQ1/P2RX7/HILPDA/PLIN2/APOC1/TRIAP1/FABP5/SYT7/SQLE/APOL3/ACSL4/ITGAV/PLSCR1/TMEM30B/KCNN4/STARD10/STOML2/NME4/FIS1/CDS1/PTGES/C1QTNF1/LIMA1/SLC25A17/HEXB/SIGMAR1/PITPNB/HDLBP/ASXL1/LDLRAP1/PPARG/SLC10A3	52
GO:0060415	muscle tissue morphogenesis	9/2053	70/18722	0.359358739427317	0.565919274688688	TGFB1/LRP2/DSP/ENG/NOTCH1/ISL1/FKBP1A/FOXC1/TGFBR3	9
GO:0003203	endocardial cushion morphogenesis	5/2053	36/18722	0.360071472360258	0.566150113773991	BMP7/ENG/NOTCH1/ISL1/TBX3	5
GO:0009225	nucleotide-sugar metabolic process	5/2053	36/18722	0.360071472360258	0.566150113773991	EXTL2/UXS1/FUT8/UGP2/GFPT1	5
GO:0045738	negative regulation of DNA repair	5/2053	36/18722	0.360071472360258	0.566150113773991	RPS3/RMI2/MAGEF1/RIF1/POLQ	5
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	5/2053	36/18722	0.360071472360258	0.566150113773991	NCF1/PLAUR/CCDC88A/HBEGF/DGKD	5
GO:0097009	energy homeostasis	5/2053	36/18722	0.360071472360258	0.566150113773991	METRNL/CD36/UBB/STAT3/EIF4G1	5
GO:1903749	positive regulation of establishment of protein localization to mitochondrion	5/2053	36/18722	0.360071472360258	0.566150113773991	RAC2/PDCD5/SAE1/NMT1/HUWE1	5
GO:0003073	regulation of systemic arterial blood pressure	12/2053	96/18722	0.360805777144656	0.566859037147927	CYBA/SOD2/CTSZ/MME/NR2F2/EMP2/KCNK6/ENPEP/GJA1/GJA5/ADRB1/RHOA	12
GO:0035282	segmentation	12/2053	96/18722	0.360805777144656	0.566859037147927	MAFB/PRKDC/NRP2/NOTCH1/LFNG/NRP1/FOXC1/BASP1/TBX3/IRX2/COBL/XRCC2	12
GO:0055017	cardiac muscle tissue growth	12/2053	96/18722	0.360805777144656	0.566859037147927	MEF2C/RUNX1/CDK1/NOTCH1/HAMP/GJA1/YAP1/PARP2/RGS2/FOXC1/TGFBR3/MAPK14	12
GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	7/2053	53/18722	0.361442314798449	0.567561865687174	PLEK/STMN1/ARRB2/MET/CXCL8/GNAI2/RGS2	7
GO:0050819	negative regulation of coagulation	7/2053	53/18722	0.361442314798449	0.567561865687174	CD9/SH2B3/ANXA5/C1QTNF1/UBASH3B/PDGFA/SERPING1	7
GO:0006029	proteoglycan metabolic process	10/2053	79/18722	0.365350687647266	0.57354896019979	HPSE/EXTL2/CHPF/SULF2/CHST15/CHST14/DSE/GPC1/B3GAT3/HS6ST2	10
GO:0007292	female gamete generation	17/2053	140/18722	0.36582892494484	0.574149502921537	TOP2A/PTK2B/LGR5/ASPM/UBB/ADAMTS1/HPGD/RAD51C/FBXO5/RPS6/BRCA2/RGS2/TTK/ERCC1/MDK/PTN/HEXB	17
GO:0019751	polyol metabolic process	14/2053	114/18722	0.368673585749669	0.577159047135988	PLEK/ISYNA1/PGP/PTAFR/PTK2B/DHFR/AKR1B1/SPHK1/PLPP3/IMPA2/NUDT4/GCH1/QDPR/GK	14
GO:0006829	zinc ion transport	4/2053	28/18722	0.36922547336618	0.577159047135988	SLC39A10/SLC39A1/TRPM2/SLC39A7	4
GO:0007064	mitotic sister chromatid cohesion	4/2053	28/18722	0.36922547336618	0.577159047135988	SMC3/CDCA5/RAD21/DSCC1	4
GO:0007141	male meiosis I	4/2053	28/18722	0.36922547336618	0.577159047135988	UBB/RAD51C/BRCA2/ING2	4
GO:0009065	glutamine family amino acid catabolic process	4/2053	28/18722	0.36922547336618	0.577159047135988	GLUL/DDAH2/OAT/PPAT	4
GO:0015740	C4-dicarboxylate transport	4/2053	28/18722	0.36922547336618	0.577159047135988	LRRC8C/SLC1A5/SLC13A3/SLC1A3	4
GO:0019098	reproductive behavior	4/2053	28/18722	0.36922547336618	0.577159047135988	APP/HDAC2/HEXB/MBD2	4
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	4/2053	28/18722	0.36922547336618	0.577159047135988	EGFR/MVP/VPS25/PTPN3	4
GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	4/2053	28/18722	0.36922547336618	0.577159047135988	SOCS3/SH2B3/SUZ12/PARP14	4
GO:0060259	regulation of feeding behavior	4/2053	28/18722	0.36922547336618	0.577159047135988	RETN/STAT3/CFAP20/EIF2AK4	4
GO:0060325	face morphogenesis	4/2053	28/18722	0.36922547336618	0.577159047135988	RRAS/ARID5B/PLEKHA1/CRISPLD1	4
GO:0060765	regulation of androgen receptor signaling pathway	4/2053	28/18722	0.36922547336618	0.577159047135988	NCOR2/PHB/PARK7/PKN1	4
GO:0086011	membrane repolarization during action potential	4/2053	28/18722	0.36922547336618	0.577159047135988	FLNA/KCNQ1/KCNE3/YWHAE	4
GO:1903671	negative regulation of sprouting angiogenesis	4/2053	28/18722	0.36922547336618	0.577159047135988	KLF2/ALOX5/SEMA6A/EPN2	4
GO:0007588	excretion	8/2053	62/18722	0.36928559699251	0.577159047135988	AQP9/HMOX1/COMT/GNAI2/GRHPR/ATP6V1B1/MDK/NFAT5	8
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	8/2053	62/18722	0.36928559699251	0.577159047135988	TGFB1/BMP7/ENG/LDLRAD4/RBPMS/SDCBP/TTK/PPARG	8
GO:0030101	natural killer cell activation	11/2053	88/18722	0.370349731432169	0.578671455362764	TYROBP/PTPRC/CORO1A/HLA-F/HLA-E/HAVCR2/FGR/SLAMF7/PBX1/PRDX1/IL18	11
GO:0031670	cellular response to nutrient	6/2053	45/18722	0.371634505088191	0.580225612940188	HMOX1/ATP2B1/VDR/FOLR1/TRIM24/PTN	6
GO:0085029	extracellular matrix assembly	6/2053	45/18722	0.371634505088191	0.580225612940188	TGFB1/LAMB1/QSOX1/DAG1/NOTCH1/RGCC	6
GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	6/2053	45/18722	0.371634505088191	0.580225612940188	SLC25A5/BNIP3L/CHCHD10/HSPA1A/NMT1/BNIP3	6
GO:0001654	eye development	43/2053	371/18722	0.373008300965002	0.582218992141003	VIM/EFEMP1/HMGB1/SKIL/KLF4/FBN2/VEGFA/FBN1/SERPINF1/RRM1/PFDN5/SCO2/TENM3/RARA/C12orf57/BMP7/ATP2B1/FLT1/MFAP5/FAT1/TFAP2A/NRP1/NOTCH2/STAT3/HDAC2/AHI1/GATA3/CDK4/PBX1/LRP5/COL4A1/HMGN1/OBSL1/IMPDH2/DLG1/TCIRG1/GLI3/FOXC1/FJX1/PTN/ACTL6A/MYO7A/MEIS2	43
GO:0048284	organelle fusion	17/2053	141/18722	0.377253930316043	0.586833788605797	CORO1A/STX11/CDK1/SAMD9/CHP1/SPHK1/SYT7/STOML2/AFG3L2/FIS1/STX10/VAV3/BNIP3/TFRC/HUWE1/EEA1/STX6	17
GO:0002062	chondrocyte differentiation	13/2053	106/18722	0.378221914281397	0.586833788605797	TGFB1/TGFBI/MEF2C/EFEMP1/RUNX1/TRPS1/SERPINH1/RUNX3/SULF2/SCIN/GLI3/MDK/MAPK14	13
GO:0006607	NLS-bearing protein import into nucleus	3/2053	20/18722	0.37828021319448	0.586833788605797	KPNB1/IPO5/NUP54	3
GO:0006837	serotonin transport	3/2053	20/18722	0.37828021319448	0.586833788605797	LILRB1/SYK/SLC6A4	3
GO:0006883	cellular sodium ion homeostasis	3/2053	20/18722	0.37828021319448	0.586833788605797	SLC8A1/SLC9A1/SLC1A3	3
GO:0016553	base conversion or substitution editing	3/2053	20/18722	0.37828021319448	0.586833788605797	APOBEC3A/APOBEC3G/APOBEC3C	3
GO:0032793	positive regulation of CREB transcription factor activity	3/2053	20/18722	0.37828021319448	0.586833788605797	VEGFA/CAMK1D/RPS6KA5	3
GO:0033005	positive regulation of mast cell activation	3/2053	20/18722	0.37828021319448	0.586833788605797	FGR/SYK/SNX4	3
GO:0043011	myeloid dendritic cell differentiation	3/2053	20/18722	0.37828021319448	0.586833788605797	SPI1/NOTCH2/ITGB8	3
GO:0043586	tongue development	3/2053	20/18722	0.37828021319448	0.586833788605797	EGFR/HDAC2/GLI3	3
GO:0046485	ether lipid metabolic process	3/2053	20/18722	0.37828021319448	0.586833788605797	LPCAT2/PLA2G7/CHPT1	3
GO:0060231	mesenchymal to epithelial transition	3/2053	20/18722	0.37828021319448	0.586833788605797	STAT1/GATA3/BASP1	3
GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	3/2053	20/18722	0.37828021319448	0.586833788605797	LRRK2/PARK7/HSPA1A	3
GO:2000010	positive regulation of protein localization to cell surface	3/2053	20/18722	0.37828021319448	0.586833788605797	TYROBP/TNF/HSP90AB1	3
GO:0021766	hippocampus development	10/2053	80/18722	0.380616239770058	0.586833788605797	RARA/BTG2/EZH2/UQCRQ/CDK6/ANXA3/GLI3/MDK/KDM6B/NME1	10
GO:0006631	fatty acid metabolic process	45/2053	390/18722	0.381089489778787	0.586833788605797	CD74/GPX1/ALOX5AP/ALOX5/HACD3/AOAH/IL1B/CD36/GSTP1/SLC27A2/C3/ACSS1/ECI1/TECR/TBXAS1/ECHS1/PDK4/ADH5/BRCA1/ACADVL/DEGS1/ECHDC2/ETFB/HPGD/AKR1B1/NUDT8/APOC1/FABP5/HADH/ACSL4/NDUFAB1/ETFA/ACAT2/MID1IP1/ABHD2/ATP6V1B1/ECI2/PTGES/MGLL/SLC25A17/HACD4/ECH1/MAPK14/PRKAG2/PPARG	45
GO:0034968	histone lysine methylation	14/2053	115/18722	0.381375673565421	0.586833788605797	DNMT1/RTF1/BRCA1/EZH2/SUZ12/SMYD2/GATA3/BRD4/KMT5A/KMT2E/DPY30/RIF1/LMNA/PWP1	14
GO:1903169	regulation of calcium ion transmembrane transport	19/2053	159/18722	0.381554338455035	0.586833788605797	CORO1A/CYBA/LYN/SLC8A1/CXCL10/PTPN6/PTK2B/VMP1/TSPAN13/CAMK2D/KCNE3/CALM2/C4orf3/VDAC1/YWHAE/SLC9A1/DMD/FKBP1A/UBASH3B	19
GO:0001990	regulation of systemic arterial blood pressure by hormone	5/2053	37/18722	0.382800499182724	0.586833788605797	CYBA/CTSZ/MME/ENPEP/RHOA	5
GO:0003176	aortic valve development	5/2053	37/18722	0.382800499182724	0.586833788605797	TNFRSF1B/TGFB1/NOTCH1/GATA3/EFNA1	5
GO:0031646	positive regulation of nervous system process	5/2053	37/18722	0.382800499182724	0.586833788605797	TNFRSF1B/PTAFR/DAG1/ITGAX/PARD3	5
GO:0043403	skeletal muscle tissue regeneration	5/2053	37/18722	0.382800499182724	0.586833788605797	CD9/GPX1/DAG1/EZH2/KLF5	5
GO:0045616	regulation of keratinocyte differentiation	5/2053	37/18722	0.382800499182724	0.586833788605797	ZFP36/NOTCH1/ZFP36L1/VDR/FOXC1	5
GO:0016482	cytosolic transport	20/2053	168/18722	0.383395132281845	0.586833788605797	LAPTM5/CORO1A/MSN/FLNA/SORL1/LRRK2/EMP2/RHOBTB3/RDX/ACTR2/SYT7/SRSF10/VPS13C/STX10/HOOK2/EZR/AKTIP/ARL1/EEA1/STX6	20
GO:0098739	import across plasma membrane	21/2053	177/18722	0.385065279738982	0.586833788605797	SLC2A3/SLC8A1/LRP2/CD36/SLC2A1/ITGB1/KCNQ1/LRRC8C/TRPV2/SLC39A10/SLC15A3/SLC6A6/TRPM2/SLC1A5/FOLR1/SLC19A1/RGS2/SLC9A1/DLG1/SLC3A2/SLC1A3	21
GO:0002024	diet induced thermogenesis	2/2053	12/18722	0.385158576588271	0.586833788605797	SORL1/ADRB1	2
GO:0002674	negative regulation of acute inflammatory response	2/2053	12/18722	0.385158576588271	0.586833788605797	GSTP1/NLRP3	2
GO:0006068	ethanol catabolic process	2/2053	12/18722	0.385158576588271	0.586833788605797	ALDH2/SULT1A1	2
GO:0006534	cysteine metabolic process	2/2053	12/18722	0.385158576588271	0.586833788605797	CDO1/GCLM	2
GO:0006563	L-serine metabolic process	2/2053	12/18722	0.385158576588271	0.586833788605797	SDS/SHMT1	2
GO:0006703	estrogen biosynthetic process	2/2053	12/18722	0.385158576588271	0.586833788605797	HSD17B1/HSD17B11	2
GO:0010587	miRNA catabolic process	2/2053	12/18722	0.385158576588271	0.586833788605797	LIN28B/SND1	2
GO:0010826	negative regulation of centrosome duplication	2/2053	12/18722	0.385158576588271	0.586833788605797	NPM1/BRCA1	2
GO:0014831	gastro-intestinal system smooth muscle contraction	2/2053	12/18722	0.385158576588271	0.586833788605797	PTAFR/SULF2	2
GO:0021670	lateral ventricle development	2/2053	12/18722	0.385158576588271	0.586833788605797	CDK6/NUMB	2
GO:0021978	telencephalon regionalization	2/2053	12/18722	0.385158576588271	0.586833788605797	ADGRG1/TRA2B	2
GO:0030238	male sex determination	2/2053	12/18722	0.385158576588271	0.586833788605797	SF1/MAP3K4	2
GO:0030397	membrane disassembly	2/2053	12/18722	0.385158576588271	0.586833788605797	VRK1/PRKCB	2
GO:0031223	auditory behavior	2/2053	12/18722	0.385158576588271	0.586833788605797	CNTNAP2/SLC1A3	2
GO:0032306	regulation of prostaglandin secretion	2/2053	12/18722	0.385158576588271	0.586833788605797	IL1B/PTGES	2
GO:0032536	regulation of cell projection size	2/2053	12/18722	0.385158576588271	0.586833788605797	TWF2/EZR	2
GO:0032908	regulation of transforming growth factor beta1 production	2/2053	12/18722	0.385158576588271	0.586833788605797	TYROBP/CD2AP	2
GO:0033127	regulation of histone phosphorylation	2/2053	12/18722	0.385158576588271	0.586833788605797	IL1B/RPS6KA5	2
GO:0033182	regulation of histone ubiquitination	2/2053	12/18722	0.385158576588271	0.586833788605797	PARK7/UBE2N	2
GO:0033235	positive regulation of protein sumoylation	2/2053	12/18722	0.385158576588271	0.586833788605797	GNL3/SAE1	2
GO:0033523	histone H2B ubiquitination	2/2053	12/18722	0.385158576588271	0.586833788605797	DTX3L/RNF8	2
GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	2/2053	12/18722	0.385158576588271	0.586833788605797	HMGB1/IFI35	2
GO:0034392	negative regulation of smooth muscle cell apoptotic process	2/2053	12/18722	0.385158576588271	0.586833788605797	ARRB2/DNMT1	2
GO:0035092	sperm chromatin condensation	2/2053	12/18722	0.385158576588271	0.586833788605797	SRPK1/RNF8	2
GO:0038180	nerve growth factor signaling pathway	2/2053	12/18722	0.385158576588271	0.586833788605797	CORO1A/RAP1A	2
GO:0042117	monocyte activation	2/2053	12/18722	0.385158576588271	0.586833788605797	LILRB4/CD33	2
GO:0042118	endothelial cell activation	2/2053	12/18722	0.385158576588271	0.586833788605797	CXCL10/PPIA	2
GO:0042762	regulation of sulfur metabolic process	2/2053	12/18722	0.385158576588271	0.586833788605797	PDK4/COMT	2
GO:0043248	proteasome assembly	2/2053	12/18722	0.385158576588271	0.586833788605797	PSMG1/PSMD11	2
GO:0043476	pigment accumulation	2/2053	12/18722	0.385158576588271	0.586833788605797	RAB32/CD63	2
GO:0043482	cellular pigment accumulation	2/2053	12/18722	0.385158576588271	0.586833788605797	RAB32/CD63	2
GO:0043696	dedifferentiation	2/2053	12/18722	0.385158576588271	0.586833788605797	HNRNPD/CDK6	2
GO:0043697	cell dedifferentiation	2/2053	12/18722	0.385158576588271	0.586833788605797	HNRNPD/CDK6	2
GO:0044650	adhesion of symbiont to host cell	2/2053	12/18722	0.385158576588271	0.586833788605797	HSP90AB1/ICAM1	2
GO:0045039	protein insertion into mitochondrial inner membrane	2/2053	12/18722	0.385158576588271	0.586833788605797	TIMM13/NDUFA13	2
GO:0045602	negative regulation of endothelial cell differentiation	2/2053	12/18722	0.385158576588271	0.586833788605797	VEGFA/ID1	2
GO:0045605	negative regulation of epidermal cell differentiation	2/2053	12/18722	0.385158576588271	0.586833788605797	NOTCH1/EZH2	2
GO:0045683	negative regulation of epidermis development	2/2053	12/18722	0.385158576588271	0.586833788605797	NOTCH1/EZH2	2
GO:0046051	UTP metabolic process	2/2053	12/18722	0.385158576588271	0.586833788605797	NME4/NME1	2
GO:0046606	negative regulation of centrosome cycle	2/2053	12/18722	0.385158576588271	0.586833788605797	NPM1/BRCA1	2
GO:0051639	actin filament network formation	2/2053	12/18722	0.385158576588271	0.586833788605797	LCP1/COBL	2
GO:0060009	Sertoli cell development	2/2053	12/18722	0.385158576588271	0.586833788605797	FLNA/ICAM1	2
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	2/2053	12/18722	0.385158576588271	0.586833788605797	LDLRAD4/PPARG	2
GO:0060453	regulation of gastric acid secretion	2/2053	12/18722	0.385158576588271	0.586833788605797	SGK1/KCNQ1	2
GO:0060788	ectodermal placode formation	2/2053	12/18722	0.385158576588271	0.586833788605797	HDAC2/TBX3	2
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	2/2053	12/18722	0.385158576588271	0.586833788605797	HAMP/PARP2	2
GO:0061307	cardiac neural crest cell differentiation involved in heart development	2/2053	12/18722	0.385158576588271	0.586833788605797	BMP7/FOLR1	2
GO:0061308	cardiac neural crest cell development involved in heart development	2/2053	12/18722	0.385158576588271	0.586833788605797	BMP7/FOLR1	2
GO:0061620	glycolytic process through glucose-6-phosphate	2/2053	12/18722	0.385158576588271	0.586833788605797	HK3/HK2	2
GO:0070943	neutrophil-mediated killing of symbiont cell	2/2053	12/18722	0.385158576588271	0.586833788605797	TREM1/MYD88	2
GO:0071107	response to parathyroid hormone	2/2053	12/18722	0.385158576588271	0.586833788605797	MEF2C/GJA1	2
GO:0071468	cellular response to acidic pH	2/2053	12/18722	0.385158576588271	0.586833788605797	CHP1/SLC9A1	2
GO:0071697	ectodermal placode morphogenesis	2/2053	12/18722	0.385158576588271	0.586833788605797	HDAC2/TBX3	2
GO:0071712	ER-associated misfolded protein catabolic process	2/2053	12/18722	0.385158576588271	0.586833788605797	SDF2L1/VCP	2
GO:0071872	cellular response to epinephrine stimulus	2/2053	12/18722	0.385158576588271	0.586833788605797	KCNQ1/SLC9A1	2
GO:0072015	glomerular visceral epithelial cell development	2/2053	12/18722	0.385158576588271	0.586833788605797	NOTCH2/ASXL1	2
GO:0072376	protein activation cascade	2/2053	12/18722	0.385158576588271	0.586833788605797	FBLN1/FN1	2
GO:0090085	regulation of protein deubiquitination	2/2053	12/18722	0.385158576588271	0.586833788605797	PARK7/VCP	2
GO:0090677	reversible differentiation	2/2053	12/18722	0.385158576588271	0.586833788605797	SOD2/DNMT1	2
GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress	2/2053	12/18722	0.385158576588271	0.586833788605797	JUN/HSPA1A	2
GO:0098974	postsynaptic actin cytoskeleton organization	2/2053	12/18722	0.385158576588271	0.586833788605797	ACTB/WASF2	2
GO:1901894	regulation of ATPase-coupled calcium transmembrane transporter activity	2/2053	12/18722	0.385158576588271	0.586833788605797	VMP1/C4orf3	2
GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	2/2053	12/18722	0.385158576588271	0.586833788605797	PLXNC1/NRP1	2
GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA	2/2053	12/18722	0.385158576588271	0.586833788605797	TGFB1/EGFR	2
GO:1905214	regulation of RNA binding	2/2053	12/18722	0.385158576588271	0.586833788605797	NUCKS1/EIF4G1	2
GO:2000035	regulation of stem cell division	2/2053	12/18722	0.385158576588271	0.586833788605797	EVI2B/CDK2AP2	2
GO:2000303	regulation of ceramide biosynthetic process	2/2053	12/18722	0.385158576588271	0.586833788605797	ORMDL1/SPHK1	2
GO:2000628	regulation of miRNA metabolic process	2/2053	12/18722	0.385158576588271	0.586833788605797	LIN28B/HRAS	2
GO:2001214	positive regulation of vasculogenesis	2/2053	12/18722	0.385158576588271	0.586833788605797	RRAS/RAP1A	2
GO:0016239	positive regulation of macroautophagy	8/2053	63/18722	0.386600578349989	0.588731845203028	HMOX1/SLC25A5/BNIP3L/SLC25A4/RALB/VDAC1/SCOC/BNIP3	8
GO:0099601	regulation of neurotransmitter receptor activity	8/2053	63/18722	0.386600578349989	0.588731845203028	MEF2C/APP/CCR2/IFNGR2/PTK2B/AKAP9/CAPN1/HOMER1	8
GO:0007009	plasma membrane organization	17/2053	142/18722	0.388729207924433	0.591673071422272	PTPRC/CXCR4/CD9/SOD1/SERP1/S100A9/SPESP1/P2RX7/DEGS1/SYT7/FOLR1/ANK3/PLSCR1/SPTBN1/FNBP1L/PACSIN3/NDRG1	17
GO:0097553	calcium ion transmembrane import into cytosol	17/2053	142/18722	0.388729207924433	0.591673071422272	PTPRC/CORO1A/CCL3/CYBA/LYN/SLC8A1/CXCL10/PTPN6/PTK2B/TRPV2/CAMK2D/TRPM2/CALM2/MCOLN3/DMD/FKBP1A/UBASH3B	17
GO:0031497	chromatin assembly	18/2053	151/18722	0.390656936606125	0.594305684492077	NASP/HMGB1/HMGB2/HELLS/DNAJC9/CENPW/NPM1/ASF1B/SET/NAP1L1/RBBP4/MCM2/HAT1/ITGB3BP/CHAF1A/MIS18A/NAP1L4/SMARCA5	18
GO:0043535	regulation of blood vessel endothelial cell migration	18/2053	151/18722	0.390656936606125	0.594305684492077	TMSB4X/TGFB1/MEF2C/HMGB1/KLF4/VEGFA/TNF/HMOX1/VASH1/NOTCH1/STAT5A/NRP1/RHOA/CIB1/RGCC/EFNA1/PLK2/PPARG	18
GO:0005977	glycogen metabolic process	9/2053	72/18722	0.391749245833409	0.595816343472865	HMGB1/PHLDA2/AGL/IL6ST/UGP2/GAA/INSR/PHKB/PRKAG2	9
GO:0007019	microtubule depolymerization	6/2053	46/18722	0.392052460011081	0.595975363584111	STMN1/CIB1/TPX2/CKAP2/MID1IP1/ARHGEF2	6
GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	6/2053	46/18722	0.392052460011081	0.595975363584111	ITGAL/CADM1/TENM3/JAML/ALCAM/ICAM1	6
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	4/2053	29/18722	0.395212472385488	0.599109356824893	ZFP36/PABPC1/BTG2/AGO2	4
GO:0002068	glandular epithelial cell development	4/2053	29/18722	0.395212472385488	0.599109356824893	RARA/RHEB/CDK6/BAD	4
GO:0006734	NADH metabolic process	4/2053	29/18722	0.395212472385488	0.599109356824893	HK3/HK2/MDH1/VCP	4
GO:0010955	negative regulation of protein processing	4/2053	29/18722	0.395212472385488	0.599109356824893	LRRK2/CTSZ/CARD16/BCL2L12	4
GO:0015701	bicarbonate transport	4/2053	29/18722	0.395212472385488	0.599109356824893	SLC26A2/CYB5R4/BEST1/CYB5R1	4
GO:0021522	spinal cord motor neuron differentiation	4/2053	29/18722	0.395212472385488	0.599109356824893	LMO4/ISL1/SOX4/GLI3	4
GO:0048265	response to pain	4/2053	29/18722	0.395212472385488	0.599109356824893	TSPO/VWA1/COMT/GCH1	4
GO:0070979	protein K11-linked ubiquitination	4/2053	29/18722	0.395212472385488	0.599109356824893	UBE2T/ANAPC11/UBE2C/UBE2S	4
GO:0095500	acetylcholine receptor signaling pathway	4/2053	29/18722	0.395212472385488	0.599109356824893	RGS10/GNA15/GNAI2/GNA11	4
GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	4/2053	29/18722	0.395212472385488	0.599109356824893	CD74/CD44/TRIAP1/ING2	4
GO:1903318	negative regulation of protein maturation	4/2053	29/18722	0.395212472385488	0.599109356824893	LRRK2/CTSZ/CARD16/BCL2L12	4
GO:0035265	organ growth	21/2053	178/18722	0.395351052282581	0.599168050946068	MEF2C/PSAP/DUSP9/RUNX1/SASH3/SOD1/RARA/CDK1/SERP1/NOTCH1/HAMP/GJA1/SLC6A4/YAP1/PARP2/RGS2/STK4/FOXC1/TGFBR3/BASP1/MAPK14	21
GO:0001942	hair follicle development	10/2053	81/18722	0.395931824278533	0.59929135864561	EGFR/TNF/LAMA5/NOTCH1/HPSE/LGR5/FERMT1/HDAC2/LGR4/PDGFA	10
GO:0021954	central nervous system neuron development	10/2053	81/18722	0.395931824278533	0.59929135864561	NR4A2/NRP2/HSP90AA1/HSP90AB1/C12orf57/BTG2/UBB/UQCRQ/NRP1/RAC3	10
GO:0030641	regulation of cellular pH	10/2053	81/18722	0.395931824278533	0.59929135864561	SLC11A1/LRRK2/GRN/HVCN1/PPT1/CHP1/DMXL2/SLC9A1/TCIRG1/ATP6V0E1	10
GO:0051149	positive regulation of muscle cell differentiation	10/2053	81/18722	0.395931824278533	0.59929135864561	TGFB1/MEF2C/SOD2/ARRB2/CAMK1/ENG/HAMP/MORF4L2/PARP2/MAPK14	10
GO:2000243	positive regulation of reproductive process	10/2053	81/18722	0.395931824278533	0.59929135864561	RETN/VEGFA/PTAFR/LHFPL2/RAD51AP1/C1QBP/CIB1/HDAC2/AGO2/DEFB1	10
GO:2000027	regulation of animal organ morphogenesis	15/2053	125/18722	0.39643179685935	0.599896792220958	VEGFA/TNF/MAGED1/BMP7/PHB2/TACSTD2/RHOA/AHI1/GATA3/LGR4/SP6/ZNRF3/PDGFA/DAAM1/GPC3	15
GO:0061098	positive regulation of protein tyrosine kinase activity	7/2053	55/18722	0.398798506898254	0.603173945396905	NCF1/FCGR1A/CSF1R/CD24/LILRA5/HBEGF/EFNA1	7
GO:1902991	regulation of amyloid precursor protein catabolic process	7/2053	55/18722	0.398798506898254	0.603173945396905	LYN/SORL1/TNF/EFNA1/FKBP1A/IFNGR1/PICALM	7
GO:0034763	negative regulation of transmembrane transport	17/2053	143/18722	0.400244522638562	0.605208451570407	OAZ1/TNF/IL1B/HAMP/PRKCB/CAMK2D/KCNE3/CALM2/FABP5/C4orf3/ANK3/VDAC1/GOPC/YWHAE/RGS2/COMMD1/PEA15	17
GO:0016125	sterol metabolic process	18/2053	152/18722	0.401834027196316	0.607305834553627	NPC2/APP/APOBR/SOD1/FDPS/DHCR24/ACADVL/SQLE/FDFT1/LRP5/LIPA/PMVK/EBP/CYB5R1/LIMA1/HDLBP/PRKAG2/LDLRAP1	18
GO:0030509	BMP signaling pathway	18/2053	152/18722	0.401834027196316	0.607305834553627	TGFB1/SORL1/SKIL/FBN1/LRP2/BMP7/ENG/NOTCH1/CRIM1/FSTL1/USP15/NOTCH2/UBE2D1/TGFBR3/SMAD5/CTDSPL2/PPARG/GPC3	18
GO:0051153	regulation of striated muscle cell differentiation	12/2053	99/18722	0.402306557935339	0.60756087279437	TGFB1/MEF2C/ARRB2/NOTCH1/HAMP/MORF4L2/EZH2/PARP2/RGS2/BHLHE41/YBX1/MAPK14	12
GO:0060291	long-term synaptic potentiation	12/2053	99/18722	0.402306557935339	0.60756087279437	TYROBP/LILRB2/APP/NSG1/MME/PTK2B/CX3CR1/STAU1/NRGN/EIF2AK4/PLK2/PTN	12
GO:0060996	dendritic spine development	12/2053	99/18722	0.402306557935339	0.60756087279437	MEF2C/ABI3/LRRK2/DOCK10/CAMK1/ACTR2/HDAC2/ACSL4/DLG5/EFNA1/PLK2/CFL1	12
GO:0006749	glutathione metabolic process	8/2053	64/18722	0.403945022736467	0.609574984008753	GPX1/GSTP1/SOD1/CLIC1/GCLM/IDH1/PARK7/GLO1	8
GO:0046579	positive regulation of Ras protein signal transduction	8/2053	64/18722	0.403945022736467	0.609574984008753	GPR65/LPAR6/ADGRG1/NOTCH1/HRAS/NOTCH2/NET1/DYNLT1	8
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	8/2053	64/18722	0.403945022736467	0.609574984008753	HLA-DRB1/UCP2/MPC2/HMGN3/KLF7/LRP5/PHPT1/BAD	8
GO:0001825	blastocyst formation	5/2053	38/18722	0.40549133742127	0.610986445135013	SKIL/JUNB/MFNG/YAP1/ACTL6A	5
GO:0008210	estrogen metabolic process	5/2053	38/18722	0.40549133742127	0.610986445135013	HSD17B1/COMT/SULT1A1/HSD17B11/PLEKHA1	5
GO:0035337	fatty-acyl-CoA metabolic process	5/2053	38/18722	0.40549133742127	0.610986445135013	TECR/PPT1/NUDT8/SLC25A1/ACSL4	5
GO:0035886	vascular associated smooth muscle cell differentiation	5/2053	38/18722	0.40549133742127	0.610986445135013	SOD2/VEGFA/DNMT1/ENG/NOTCH1	5
GO:0071392	cellular response to estradiol stimulus	5/2053	38/18722	0.40549133742127	0.610986445135013	EGFR/FAM210B/CCNA2/HNRNPD/DDX18	5
GO:1901186	positive regulation of ERBB signaling pathway	5/2053	38/18722	0.40549133742127	0.610986445135013	NCF1/PLAUR/CCDC88A/HBEGF/DGKD	5
GO:0019216	regulation of lipid metabolic process	38/2053	331/18722	0.407184013966143	0.613382898266848	TSPO/CD74/TGFB1/LYN/SORL1/NPC2/PSAP/FGR/TNF/IL1B/C3/LACTB/SOD1/TREM2/PTK2B/PDK4/ORMDL1/BRCA1/ACADVL/PHB2/FLT1/CHP1/APOC1/SPHK1/FABP5/SF1/CDK4/MID1IP1/STOML2/DNAJC19/IDH1/VAV3/ID2/PTK2/PDGFA/PRKAG2/LDLRAP1/PPARG	38
GO:0006073	cellular glucan metabolic process	9/2053	73/18722	0.408000214019381	0.613590418535566	HMGB1/PHLDA2/AGL/IL6ST/UGP2/GAA/INSR/PHKB/PRKAG2	9
GO:0035773	insulin secretion involved in cellular response to glucose stimulus	9/2053	73/18722	0.408000214019381	0.613590418535566	HLA-DRB1/UCP2/MPC2/HMGN3/KLF7/LRP5/PHPT1/BAD/CCDC186	9
GO:0044042	glucan metabolic process	9/2053	73/18722	0.408000214019381	0.613590418535566	HMGB1/PHLDA2/AGL/IL6ST/UGP2/GAA/INSR/PHKB/PRKAG2	9
GO:0002689	negative regulation of leukocyte chemotaxis	3/2053	21/18722	0.409264809163222	0.613590418535566	DUSP1/DPP4/RIN3	3
GO:0006450	regulation of translational fidelity	3/2053	21/18722	0.409264809163222	0.613590418535566	RPS5/IARS2/RPS9	3
GO:0007063	regulation of sister chromatid cohesion	3/2053	21/18722	0.409264809163222	0.613590418535566	FEN1/CDCA5/RAD21	3
GO:0007289	spermatid nucleus differentiation	3/2053	21/18722	0.409264809163222	0.613590418535566	HMGB2/SRPK1/RNF8	3
GO:0007617	mating behavior	3/2053	21/18722	0.409264809163222	0.613590418535566	APP/HDAC2/HEXB	3
GO:0032303	regulation of icosanoid secretion	3/2053	21/18722	0.409264809163222	0.613590418535566	IL1B/SYK/PTGES	3
GO:0034035	purine ribonucleoside bisphosphate metabolic process	3/2053	21/18722	0.409264809163222	0.613590418535566	SLC26A2/SULT1A1/TPST2	3
GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	3/2053	21/18722	0.409264809163222	0.613590418535566	GMFG/WAS/WASF2	3
GO:0045717	negative regulation of fatty acid biosynthetic process	3/2053	21/18722	0.409264809163222	0.613590418535566	BRCA1/ACADVL/APOC1	3
GO:0046128	purine ribonucleoside metabolic process	3/2053	21/18722	0.409264809163222	0.613590418535566	MTAP/PNP/ADK	3
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	3/2053	21/18722	0.409264809163222	0.613590418535566	SLC26A2/SULT1A1/TPST2	3
GO:0072170	metanephric tubule development	3/2053	21/18722	0.409264809163222	0.613590418535566	STAT1/LGR4/YAP1	3
GO:0072243	metanephric nephron epithelium development	3/2053	21/18722	0.409264809163222	0.613590418535566	STAT1/LGR4/YAP1	3
GO:1903429	regulation of cell maturation	3/2053	21/18722	0.409264809163222	0.613590418535566	CLEC7A/LRRK2/RAC3	3
GO:1905209	positive regulation of cardiocyte differentiation	3/2053	21/18722	0.409264809163222	0.613590418535566	TGFB1/MEF2C/ARRB2	3
GO:2001014	regulation of skeletal muscle cell differentiation	3/2053	21/18722	0.409264809163222	0.613590418535566	MEF2C/UQCC2/GPC1	3
GO:0010324	membrane invagination	17/2053	144/18722	0.411789685489926	0.617221612025869	AIF1/ITGB2/FCGR1A/MSR1/NCKAP1L/CD300A/RAC2/ITGAM/CD36/C3/TREM2/ARHGAP25/MARCO/RHOA/FNBP1L/RHOG/AURKB	17
GO:0048483	autonomic nervous system development	6/2053	47/18722	0.41244956276326	0.617901966686531	FN1/NRP2/TFAP2A/NRP1/SOX4/GATA3	6
GO:0120163	negative regulation of cold-induced thermogenesis	6/2053	47/18722	0.41244956276326	0.617901966686531	TLR4/NOTCH1/ID1/ALDH1A1/RHEB/LGR4	6
GO:0007033	vacuole organization	21/2053	180/18722	0.416012038516951	0.622927933891117	LAPTM5/CORO1A/LRRK2/GRN/LYST/VMP1/PPT1/TPP1/SYT7/RALB/UBXN2A/HOOK2/TCIRG1/GAA/ATG16L2/AKTIP/HEXB/GABARAP/TMEM41B/WIPI2/MYO7A	21
GO:0015698	inorganic anion transport	21/2053	180/18722	0.416012038516951	0.622927933891117	TSPO/SLC11A1/PTAFR/CEBPB/FXYD3/SLC26A2/CLDN4/SLC25A3/KCNQ1/LRRC8C/SLC22A11/SLC13A4/CLIC1/SLC20A1/VDAC1/TTYH3/GABRE/BEST1/VDAC3/PCYOX1/SLC1A3	21
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	7/2053	56/18722	0.417481681961609	0.624816685400263	ZFP36/ZFP36L2/PABPC1/ZFP36L1/BTG2/EXOSC8/AGO2	7
GO:0030166	proteoglycan biosynthetic process	7/2053	56/18722	0.417481681961609	0.624816685400263	EXTL2/CHPF/CHST15/CHST14/DSE/B3GAT3/HS6ST2	7
GO:0048588	developmental cell growth	27/2053	234/18722	0.419674509426298	0.625724786137103	CXCR4/FN1/SPP1/VEGFA/APP/ITGA4/NRP2/HSP90AA1/HSP90AB1/ITGB1/ALCAM/SEMA4A/ARHGAP4/HAMP/TRPV2/SEMA6A/ITSN2/NRP1/GOLGA4/TWF2/SEMA6D/PARP2/EIF2AK4/RGS2/VCL/PAK6/COBL	27
GO:0060560	developmental growth involved in morphogenesis	27/2053	234/18722	0.419674509426298	0.625724786137103	CXCR4/FN1/SPP1/VEGFA/APP/ITGA4/NRP2/HSP90AA1/HSP90AB1/ITGB1/ALCAM/SEMA4A/NOTCH1/ARHGAP4/TRPV2/SEMA6A/ITSN2/NRP1/GOLGA4/TWF2/SEMA6D/YAP1/EIF2AK4/VCL/PAK6/TRIM28/COBL	27
GO:0007613	memory	14/2053	118/18722	0.419723706312236	0.625724786137103	SERPINF1/CEBPB/SGK1/FEN1/TREM2/COMT/CX3CR1/SLC6A4/EIF2AK4/PAK6/INSR/MDK/PLK2/PTN	14
GO:0090305	nucleic acid phosphodiester bond hydrolysis	30/2053	261/18722	0.420793336848013	0.625724786137103	ZFP36/SAMHD1/RPS21/ISG20/RNASE6/FEN1/RNASET2/POP7/EXOSC8/RNASEH2A/NHP2/POLR3K/N4BP2/TSEN34/POLR2I/PLSCR1/RAD50/PNKP/SND1/DNASE1L1/APEX1/MGME1/DDX1/ERCC1/AGO2/RBBP8/EXO1/TOE1/LACTB2/BMS1	30
GO:0007176	regulation of epidermal growth factor-activated receptor activity	4/2053	30/18722	0.421020777301445	0.625724786137103	NCF1/APP/HBEGF/VPS25	4
GO:0009072	aromatic amino acid family metabolic process	4/2053	30/18722	0.421020777301445	0.625724786137103	KYNU/IL4I1/PARK7/QDPR	4
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	4/2053	30/18722	0.421020777301445	0.625724786137103	SLC8A1/CAMK2D/CALM2/DMD	4
GO:0033137	negative regulation of peptidyl-serine phosphorylation	4/2053	30/18722	0.421020777301445	0.625724786137103	DDIT4/RASSF2/DMD/PWP1	4
GO:0036296	response to increased oxygen levels	4/2053	30/18722	0.421020777301445	0.625724786137103	HDAC2/CDK4/CDKN1A/BNIP3	4
GO:0051491	positive regulation of filopodium assembly	4/2053	30/18722	0.421020777301445	0.625724786137103	NRP1/FNBP1L/RHOQ/DOCK11	4
GO:0051968	positive regulation of synaptic transmission, glutamatergic	4/2053	30/18722	0.421020777301445	0.625724786137103	EGFR/CCR2/GLUL/PTK2B	4
GO:0060218	hematopoietic stem cell differentiation	4/2053	30/18722	0.421020777301445	0.625724786137103	PRKDC/XRCC5/FOXC1/HSPA9	4
GO:0061311	cell surface receptor signaling pathway involved in heart development	4/2053	30/18722	0.421020777301445	0.625724786137103	TGFB1/GALNT11/NOTCH1/NOTCH2	4
GO:1903019	negative regulation of glycoprotein metabolic process	4/2053	30/18722	0.421020777301445	0.625724786137103	CST3/HBEGF/ITM2C/AGO2	4
GO:0043401	steroid hormone mediated signaling pathway	16/2053	136/18722	0.422311977075513	0.625724786137103	JAK2/PARP1/BMP7/CALR/BRCA1/PHB2/ISL1/RHOA/NCOR2/YAP1/ABHD2/PHB/PGRMC2/PARK7/SKP2/PKN1	16
GO:0099024	plasma membrane invagination	16/2053	136/18722	0.422311977075513	0.625724786137103	AIF1/ITGB2/FCGR1A/MSR1/NCKAP1L/CD300A/RAC2/ITGAM/CD36/C3/TREM2/ARHGAP25/MARCO/RHOA/RHOG/AURKB	16
GO:0046470	phosphatidylcholine metabolic process	9/2053	74/18722	0.424250914078488	0.625724786137103	LPCAT2/PLA2G7/DBI/CHPT1/APOC1/FABP5/CDS1/SLC44A1/SLC44A2	9
GO:0048332	mesoderm morphogenesis	9/2053	74/18722	0.424250914078488	0.625724786137103	KLF4/WLS/BMP7/ITGB1/ITGB4/GJA1/FOXC1/KDM6B/TBX3	9
GO:0070972	protein localization to endoplasmic reticulum	9/2053	74/18722	0.424250914078488	0.625724786137103	LRRK2/HSPA5/GJA1/SPCS2/GPAA1/SEC63/PPP1R15A/SGTB/KDELR2	9
GO:0002638	negative regulation of immunoglobulin production	2/2053	13/18722	0.425388567108874	0.625724786137103	PRKDC/BCL6	2
GO:0003222	ventricular trabecula myocardium morphogenesis	2/2053	13/18722	0.425388567108874	0.625724786137103	ENG/NOTCH1	2
GO:0005513	detection of calcium ion	2/2053	13/18722	0.425388567108874	0.625724786137103	KCNMB1/CALM2	2
GO:0006264	mitochondrial DNA replication	2/2053	13/18722	0.425388567108874	0.625724786137103	STOML2/MGME1	2
GO:0006586	indolalkylamine metabolic process	2/2053	13/18722	0.425388567108874	0.625724786137103	KYNU/IL4I1	2
GO:0006983	ER overload response	2/2053	13/18722	0.425388567108874	0.625724786137103	CCDC47/HSPA5	2
GO:0007494	midgut development	2/2053	13/18722	0.425388567108874	0.625724786137103	EGFR/ASS1	2
GO:0007567	parturition	2/2053	13/18722	0.425388567108874	0.625724786137103	PTAFR/HPGD	2
GO:0008298	intracellular mRNA localization	2/2053	13/18722	0.425388567108874	0.625724786137103	ZFP36/ZFP36L1	2
GO:0009134	nucleoside diphosphate catabolic process	2/2053	13/18722	0.425388567108874	0.625724786137103	ENTPD1/NUDT5	2
GO:0010755	regulation of plasminogen activation	2/2053	13/18722	0.425388567108874	0.625724786137103	RUNX1/CTSZ	2
GO:0010958	regulation of amino acid import across plasma membrane	2/2053	13/18722	0.425388567108874	0.625724786137103	ITGB1/RGS2	2
GO:0010960	magnesium ion homeostasis	2/2053	13/18722	0.425388567108874	0.625724786137103	EGFR/ANK3	2
GO:0014745	negative regulation of muscle adaptation	2/2053	13/18722	0.425388567108874	0.625724786137103	KLF4/LMNA	2
GO:0014842	regulation of skeletal muscle satellite cell proliferation	2/2053	13/18722	0.425388567108874	0.625724786137103	JAK2/STAT3	2
GO:0015809	arginine transport	2/2053	13/18722	0.425388567108874	0.625724786137103	SLC11A1/SLC38A9	2
GO:0016024	CDP-diacylglycerol biosynthetic process	2/2053	13/18722	0.425388567108874	0.625724786137103	AGPAT2/CDS1	2
GO:0021514	ventral spinal cord interneuron differentiation	2/2053	13/18722	0.425388567108874	0.625724786137103	LMO4/GLI3	2
GO:0021554	optic nerve development	2/2053	13/18722	0.425388567108874	0.625724786137103	TCIRG1/GLI3	2
GO:0021819	layer formation in cerebral cortex	2/2053	13/18722	0.425388567108874	0.625724786137103	ADGRG1/GLI3	2
GO:0030836	positive regulation of actin filament depolymerization	2/2053	13/18722	0.425388567108874	0.625724786137103	PLEK/DSTN	2
GO:0032042	mitochondrial DNA metabolic process	2/2053	13/18722	0.425388567108874	0.625724786137103	PARP1/MGME1	2
GO:0032429	regulation of phospholipase A2 activity	2/2053	13/18722	0.425388567108874	0.625724786137103	EGFR/PPT1	2
GO:0032905	transforming growth factor beta1 production	2/2053	13/18722	0.425388567108874	0.625724786137103	TYROBP/CD2AP	2
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	2/2053	13/18722	0.425388567108874	0.625724786137103	SUPT16H/BRD4	2
GO:0035331	negative regulation of hippo signaling	2/2053	13/18722	0.425388567108874	0.625724786137103	DLG5/MAPK14	2
GO:0036302	atrioventricular canal development	2/2053	13/18722	0.425388567108874	0.625724786137103	ENG/TBX3	2
GO:0042659	regulation of cell fate specification	2/2053	13/18722	0.425388567108874	0.625724786137103	LMO4/ESRP1	2
GO:0044090	positive regulation of vacuole organization	2/2053	13/18722	0.425388567108874	0.625724786137103	GRN/RALB	2
GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	2/2053	13/18722	0.425388567108874	0.625724786137103	NCF1/HBEGF	2
GO:0046415	urate metabolic process	2/2053	13/18722	0.425388567108874	0.625724786137103	SLC22A11/PNP	2
GO:0046642	negative regulation of alpha-beta T cell proliferation	2/2053	13/18722	0.425388567108874	0.625724786137103	LGALS9/TNFRSF14	2
GO:0048266	behavioral response to pain	2/2053	13/18722	0.425388567108874	0.625724786137103	TSPO/VWA1	2
GO:0051451	myoblast migration	2/2053	13/18722	0.425388567108874	0.625724786137103	PLEKHO1/NET1	2
GO:0051481	negative regulation of cytosolic calcium ion concentration	2/2053	13/18722	0.425388567108874	0.625724786137103	SLC8A1/ATP2B1	2
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	2/2053	13/18722	0.425388567108874	0.625724786137103	ECT2/AURKB	2
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	2/2053	13/18722	0.425388567108874	0.625724786137103	IRF7/NLRC5	2
GO:0061615	glycolytic process through fructose-6-phosphate	2/2053	13/18722	0.425388567108874	0.625724786137103	HK3/HK2	2
GO:0061744	motor behavior	2/2053	13/18722	0.425388567108874	0.625724786137103	C12orf57/DPP4	2
GO:0070234	positive regulation of T cell apoptotic process	2/2053	13/18722	0.425388567108874	0.625724786137103	LGALS9/ADAM8	2
GO:0070254	mucus secretion	2/2053	13/18722	0.425388567108874	0.625724786137103	CYBA/EGFR	2
GO:0070316	regulation of G0 to G1 transition	2/2053	13/18722	0.425388567108874	0.625724786137103	CHEK1/FOXO4	2
GO:0072310	glomerular epithelial cell development	2/2053	13/18722	0.425388567108874	0.625724786137103	NOTCH2/ASXL1	2
GO:0090042	tubulin deacetylation	2/2053	13/18722	0.425388567108874	0.625724786137103	FLNA/BEX4	2
GO:0090153	regulation of sphingolipid biosynthetic process	2/2053	13/18722	0.425388567108874	0.625724786137103	ORMDL1/SPHK1	2
GO:1900121	negative regulation of receptor binding	2/2053	13/18722	0.425388567108874	0.625724786137103	B2M/PTPRF	2
GO:1902260	negative regulation of delayed rectifier potassium channel activity	2/2053	13/18722	0.425388567108874	0.625724786137103	KCNE3/ANK3	2
GO:1903789	regulation of amino acid transmembrane transport	2/2053	13/18722	0.425388567108874	0.625724786137103	ITGB1/RGS2	2
GO:1904478	regulation of intestinal absorption	2/2053	13/18722	0.425388567108874	0.625724786137103	HAMP/EPB41	2
GO:1905038	regulation of membrane lipid metabolic process	2/2053	13/18722	0.425388567108874	0.625724786137103	ORMDL1/SPHK1	2
GO:2000318	positive regulation of T-helper 17 type immune response	2/2053	13/18722	0.425388567108874	0.625724786137103	CLEC7A/NFKBIZ	2
GO:0007219	Notch signaling pathway	20/2053	172/18722	0.425758801576453	0.626115884671255	CFD/PERP/APP/CD46/NFKBIA/BMP7/GALNT11/NOTCH1/BCL6/LFNG/BMP2K/MFNG/AAK1/NOTCH2/STAT3/IL6ST/EPN2/YAP1/DTX3L/FOXC1	20
GO:0051154	negative regulation of striated muscle cell differentiation	5/2053	39/18722	0.428071874759894	0.62936320719416	NOTCH1/EZH2/RGS2/BHLHE41/YBX1	5
GO:1903351	cellular response to dopamine	11/2053	92/18722	0.428539953925711	0.629897041537058	FLNA/LRRK2/GNAS/ARRB2/TGM2/NSG1/GNA15/ID1/HRH2/HDAC2/GNA11	11
GO:0018958	phenol-containing compound metabolic process	13/2053	110/18722	0.431437868057353	0.634001275616977	ITGB2/ZEB2/CTSB/ITGAM/NR4A2/COMT/PNKD/SULT1A1/AKR1B1/EPAS1/GATA3/PARK7/GCH1	13
GO:0090090	negative regulation of canonical Wnt signaling pathway	16/2053	137/18722	0.43425960667396	0.637991586690441	PFDN5/NOTCH1/NOTUM/TPBG/FERMT1/ISL1/SIAH2/TLE1/GLI3/STK4/MDK/CTNND1/ZNRF3/PTPRU/MAPK14/GPC3	16
GO:0048813	dendrite morphogenesis	17/2053	146/18722	0.434929182472212	0.638818872664203	PHACTR1/ABI3/LRRK2/DOCK10/MEF2A/ITGB1/ID1/TPBG/NRP1/KLF7/ACTR2/EFNA1/OBSL1/RERE/PICALM/PTN/CFL1	17
GO:0051147	regulation of muscle cell differentiation	18/2053	155/18722	0.435498817739731	0.639498998149385	TGFB1/MEF2C/SOD2/ARRB2/CAMK1/DNMT1/ENG/NOTCH1/HAMP/MORF4L2/EZH2/PARP2/FOXO4/RGS2/ID2/BHLHE41/YBX1/MAPK14	18
GO:0051155	positive regulation of striated muscle cell differentiation	7/2053	57/18722	0.436113209546487	0.639931341961096	TGFB1/MEF2C/ARRB2/HAMP/MORF4L2/PARP2/MAPK14	7
GO:0051205	protein insertion into membrane	7/2053	57/18722	0.436113209546487	0.639931341961096	EGFR/HSP90AA1/CCDC47/TIMM13/PDCD5/NMT1/NDUFA13	7
GO:0097120	receptor localization to synapse	7/2053	57/18722	0.436113209546487	0.639931341961096	TYROBP/NSG1/DAG1/HRAS/RAP1A/DLG1/CLSTN1	7
GO:0006814	sodium ion transport	28/2053	245/18722	0.437969791587067	0.642498471765869	FXYD5/SLC8A1/FXYD3/SGK1/SLC38A1/GLRX/KCNQ1/P2RX7/CAMK2D/KCNE3/SLC6A6/CHP1/TRPM2/SLC6A4/SLC13A4/ANK3/SLC20A1/MAGED2/SLC9A1/SLC13A3/ATP6V1B1/COMMD1/DLG1/DMD/PTPN3/SLC38A6/ACTN4/SLC3A2	28
GO:1905953	negative regulation of lipid localization	8/2053	66/18722	0.438587701830377	0.643076120614131	TNF/NFKBIA/TREM2/APOC1/ITGAV/FIS1/ASXL1/PPARG	8
GO:0002053	positive regulation of mesenchymal cell proliferation	3/2053	22/18722	0.43975688714663	0.643076120614131	STAT1/LRP5/PDGFA	3
GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	3/2053	22/18722	0.43975688714663	0.643076120614131	CD9/SPESP1/FOLR1	3
GO:0016137	glycoside metabolic process	3/2053	22/18722	0.43975688714663	0.643076120614131	AKR7A2/AKR1B1/FUCA1	3
GO:0019400	alditol metabolic process	3/2053	22/18722	0.43975688714663	0.643076120614131	PGP/AKR1B1/GK	3
GO:0032693	negative regulation of interleukin-10 production	3/2053	22/18722	0.43975688714663	0.643076120614131	TYROBP/LILRB1/LILRB4	3
GO:0032700	negative regulation of interleukin-17 production	3/2053	22/18722	0.43975688714663	0.643076120614131	NCKAP1L/TLR4/IL27RA	3
GO:0035089	establishment of apical/basal cell polarity	3/2053	22/18722	0.43975688714663	0.643076120614131	MSN/FAT1/RHOA	3
GO:0045663	positive regulation of myoblast differentiation	3/2053	22/18722	0.43975688714663	0.643076120614131	MEF2C/BTG1/MAPK14	3
GO:0046628	positive regulation of insulin receptor signaling pathway	3/2053	22/18722	0.43975688714663	0.643076120614131	SORL1/NUCKS1/GNAI2	3
GO:0090280	positive regulation of calcium ion import	3/2053	22/18722	0.43975688714663	0.643076120614131	CCL3/LGALS3/TRPV2	3
GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	3/2053	22/18722	0.43975688714663	0.643076120614131	VEGFA/NOTCH1/SMAD5	3
GO:2000725	regulation of cardiac muscle cell differentiation	3/2053	22/18722	0.43975688714663	0.643076120614131	TGFB1/MEF2C/ARRB2	3
GO:0006024	glycosaminoglycan biosynthetic process	9/2053	75/18722	0.440474256056688	0.643968210609193	TGFB1/IL1B/CHPF/HS3ST1/CHST15/CHST14/DSE/B3GAT3/HS6ST2	9
GO:0006112	energy reserve metabolic process	10/2053	84/18722	0.441941887536638	0.645170638739617	HMGB1/PHLDA2/AGL/IL6ST/UGP2/GAA/INSR/PHKB/GFPT1/PRKAG2	10
GO:0006835	dicarboxylic acid transport	10/2053	84/18722	0.441941887536638	0.645170638739617	LRP2/SLC26A2/ITGB1/LRRC8C/GJA1/SLC1A5/FOLR1/SLC19A1/SLC13A3/SLC1A3	10
GO:0022404	molting cycle process	10/2053	84/18722	0.441941887536638	0.645170638739617	EGFR/TNF/LAMA5/NOTCH1/HPSE/LGR5/FERMT1/HDAC2/LGR4/PDGFA	10
GO:0022405	hair cycle process	10/2053	84/18722	0.441941887536638	0.645170638739617	EGFR/TNF/LAMA5/NOTCH1/HPSE/LGR5/FERMT1/HDAC2/LGR4/PDGFA	10
GO:0061157	mRNA destabilization	10/2053	84/18722	0.441941887536638	0.645170638739617	ZFP36/ZFP36L2/PABPC1/ZFP36L1/HNRNPR/BTG2/EXOSC8/HNRNPD/KHSRP/AGO2	10
GO:0097061	dendritic spine organization	10/2053	84/18722	0.441941887536638	0.645170638739617	ABI3/LRRK2/DOCK10/TREM2/ACTR2/EFNA1/IGF1R/INSR/CFL1/HOMER1	10
GO:0106027	neuron projection organization	11/2053	93/18722	0.443099823113807	0.646546434504582	ABI3/LRRK2/DOCK10/APP/TREM2/ACTR2/EFNA1/IGF1R/INSR/CFL1/HOMER1	11
GO:1903350	response to dopamine	11/2053	93/18722	0.443099823113807	0.646546434504582	FLNA/LRRK2/GNAS/ARRB2/TGM2/NSG1/GNA15/ID1/HRH2/HDAC2/GNA11	11
GO:0048593	camera-type eye morphogenesis	14/2053	120/18722	0.445353087546723	0.649374570414826	VEGFA/TENM3/C12orf57/BMP7/FAT1/TFAP2A/NOTCH2/AHI1/LRP5/HMGN1/OBSL1/GLI3/FJX1/PTN	14
GO:0006022	aminoglycan metabolic process	15/2053	129/18722	0.445827689415923	0.649374570414826	CD44/TGFB1/ITIH5/IL1B/CHPF/HS3ST1/FUCA1/CHST15/IDS/CHST14/DSE/FOXC1/B3GAT3/HEXB/HS6ST2	15
GO:1902652	secondary alcohol metabolic process	17/2053	147/18722	0.446503594075393	0.649374570414826	NPC2/APP/APOBR/SOD1/FDPS/DHCR24/ACADVL/IDH2/SQLE/FDFT1/LRP5/PMVK/IDH1/EBP/LIMA1/HDLBP/LDLRAP1	17
GO:0002717	positive regulation of natural killer cell mediated immunity	4/2053	31/18722	0.446553246255262	0.649374570414826	HLA-F/HLA-E/CADM1/VAV1	4
GO:0008045	motor neuron axon guidance	4/2053	31/18722	0.446553246255262	0.649374570414826	RAC2/ALCAM/NRP1/RHOG	4
GO:0030212	hyaluronan metabolic process	4/2053	31/18722	0.446553246255262	0.649374570414826	CD44/TGFB1/ITIH5/IL1B	4
GO:0032509	endosome transport via multivesicular body sorting pathway	4/2053	31/18722	0.446553246255262	0.649374570414826	LYST/CHMP4C/VPS25/VCP	4
GO:0048566	embryonic digestive tract development	4/2053	31/18722	0.446553246255262	0.649374570414826	TNF/CXCL8/GLI3/ID2	4
GO:0051443	positive regulation of ubiquitin-protein transferase activity	4/2053	31/18722	0.446553246255262	0.649374570414826	UBE2C/UBE2S/RPS2/UBE2N	4
GO:0070723	response to cholesterol	4/2053	31/18722	0.446553246255262	0.649374570414826	CCL3/TGFB1/DAG1/PMVK	4
GO:0097106	postsynaptic density organization	4/2053	31/18722	0.446553246255262	0.649374570414826	LILRB2/ABI3/ZDHHC12/DLG1	4
GO:1901797	negative regulation of signal transduction by p53 class mediator	4/2053	31/18722	0.446553246255262	0.649374570414826	CD74/CD44/TRIAP1/ING2	4
GO:1905144	response to acetylcholine	4/2053	31/18722	0.446553246255262	0.649374570414826	RGS10/GNA15/GNAI2/GNA11	4
GO:1905145	cellular response to acetylcholine	4/2053	31/18722	0.446553246255262	0.649374570414826	RGS10/GNA15/GNAI2/GNA11	4
GO:1901617	organic hydroxy compound biosynthetic process	27/2053	237/18722	0.447012121864021	0.649884354539406	ZEB2/PLEK/ISYNA1/TNF/NR4A2/PGP/PTAFR/SLC27A2/SOD1/FDPS/HSD17B1/PTK2B/DHCR24/DHFR/AKR1B1/SPHK1/SQLE/GATA3/FDFT1/PMVK/IMPA2/EBP/PARK7/GCH1/CYB5R1/QDPR/PRKAG2	27
GO:0006730	one-carbon metabolic process	5/2053	40/18722	0.450474918484124	0.654442980848607	TYMS/DHFR/SFXN3/SFXN1/SHMT1	5
GO:0007339	binding of sperm to zona pellucida	5/2053	40/18722	0.450474918484124	0.654442980848607	ALDOA/TCP1/CCT2/CCT4/CCT8	5
GO:2000142	regulation of DNA-templated transcription, initiation	5/2053	40/18722	0.450474918484124	0.654442980848607	HMGB1/CDK4/JUN/ERCC1/ZNF451	5
GO:0006376	mRNA splice site selection	6/2053	49/18722	0.452972707108995	0.656640793103158	CELF2/PSIP1/SF1/SRSF10/SF3A3/LUC7L3	6
GO:0008038	neuron recognition	6/2053	49/18722	0.452972707108995	0.656640793103158	CXCR4/APP/BSG/CNTNAP2/NRP1/PALLD	6
GO:0030195	negative regulation of blood coagulation	6/2053	49/18722	0.452972707108995	0.656640793103158	CD9/SH2B3/C1QTNF1/UBASH3B/PDGFA/SERPING1	6
GO:0035088	establishment or maintenance of apical/basal cell polarity	6/2053	49/18722	0.452972707108995	0.656640793103158	MSN/FAT1/RHOA/PARD3/DLG5/DLG1	6
GO:0046605	regulation of centrosome cycle	6/2053	49/18722	0.452972707108995	0.656640793103158	NPM1/BRCA1/ATF5/CENPJ/CHMP4C/PLK2	6
GO:0051445	regulation of meiotic cell cycle	6/2053	49/18722	0.452972707108995	0.656640793103158	DUSP1/RAD51AP1/CALR/ASPM/FBXO5/TTK	6
GO:0061245	establishment or maintenance of bipolar cell polarity	6/2053	49/18722	0.452972707108995	0.656640793103158	MSN/FAT1/RHOA/PARD3/DLG5/DLG1	6
GO:0072666	establishment of protein localization to vacuole	6/2053	49/18722	0.452972707108995	0.656640793103158	LAPTM5/SORL1/TNFAIP3/HSPA8/VPS13C/VPS25	6
GO:0086009	membrane repolarization	6/2053	49/18722	0.452972707108995	0.656640793103158	FLNA/KCNQ1/KCNE3/GJA5/YWHAE/AKAP9	6
GO:0006513	protein monoubiquitination	8/2053	67/18722	0.45582158441908	0.660132634929877	UBE2T/DTL/UBB/DDB1/DTX3L/FANCL/UHRF1/HUWE1	8
GO:0006879	cellular iron ion homeostasis	8/2053	67/18722	0.45582158441908	0.660132634929877	SLC11A1/FTH1/FTL/HMOX1/SLC40A1/SOD1/HAMP/TFRC	8
GO:0009880	embryonic pattern specification	8/2053	67/18722	0.45582158441908	0.660132634929877	NRP2/BMP7/NRP1/SMAD5/BASP1/TBX3/COBL/MEIS2	8
GO:1903317	regulation of protein maturation	8/2053	67/18722	0.45582158441908	0.660132634929877	LRRK2/RUNX1/CTSZ/CARD16/ADAM8/SOX4/BCL2L12/BAG2	8
GO:0021536	diencephalon development	9/2053	76/18722	0.456644046095182	0.660845218661624	CDH1/NR4A2/NRP2/UBB/UQCRQ/CNTNAP2/NRP1/ISL1/PTN	9
GO:0043536	positive regulation of blood vessel endothelial cell migration	9/2053	76/18722	0.456644046095182	0.660845218661624	TMSB4X/TGFB1/HMGB1/VEGFA/HMOX1/STAT5A/NRP1/CIB1/PLK2	9
GO:0140029	exocytic process	9/2053	76/18722	0.456644046095182	0.660845218661624	PLEK/LYN/STXBP2/BTK/STX11/SYK/SNX4/RALB/RAB3D	9
GO:0098773	skin epidermis development	10/2053	85/18722	0.457223546132218	0.661524301131736	EGFR/TNF/LAMA5/NOTCH1/HPSE/LGR5/FERMT1/HDAC2/LGR4/PDGFA	10
GO:0002042	cell migration involved in sprouting angiogenesis	11/2053	94/18722	0.457625642212242	0.661615774755314	KLF4/VEGFA/HMOX1/ITGB1/NOTCH1/NR4A1/NRP1/RHOA/CIB1/EPHB4/PLK2	11
GO:0050954	sensory perception of mechanical stimulus	20/2053	175/18722	0.457668371821989	0.661615774755314	CXCR4/GPX1/MBP/LRP2/SOD1/ALDH7A1/KCNQ1/ICAM1/BIRC5/TIMM13/NDUFB9/TFAP2A/ATP6V1B1/USP53/EPS8L2/TBL1X/HEXB/TRIOBP/SLC1A3/MYO7A	20
GO:0030004	cellular monovalent inorganic cation homeostasis	12/2053	103/18722	0.4578944468457	0.661615774755314	SLC11A1/SLC8A1/LRRK2/GRN/HVCN1/PPT1/CHP1/DMXL2/SLC9A1/TCIRG1/ATP6V0E1/SLC1A3	12
GO:0007030	Golgi organization	18/2053	157/18722	0.457961990668966	0.661615774755314	LRRK2/LMAN1/PLK3/TMED4/CDK1/VRK1/VMP1/TMED9/GOLGB1/TMED3/PDE4DIP/OBSL1/UBXN2A/ARHGAP21/AKAP9/HUWE1/ARL1/STX6	18
GO:0007034	vacuolar transport	18/2053	157/18722	0.457961990668966	0.661615774755314	LAPTM5/SORL1/PSAP/LRRK2/GRN/LYST/DENND3/HSPA8/DTX3L/VPS13C/HMGXB4/HOOK2/HSPA1A/RHOB/CHMP4C/VPS25/VCP/AKTIP	18
GO:0000956	nuclear-transcribed mRNA catabolic process	13/2053	112/18722	0.458060770842717	0.661615774755314	ZFP36/ZFP36L2/PABPC1/ZFP36L1/BTG2/EXOSC8/LSM4/UPF3A/MAGOHB/LSM7/MAGOH/AGO2/MRTO4	13
GO:0048640	negative regulation of developmental growth	13/2053	112/18722	0.458060770842717	0.661615774755314	PLAC8/SPP1/SEMA4A/ARHGAP4/SEMA6A/GJA1/NRP1/SLC6A4/ADRB1/SEMA6D/RGS2/CDKN1A/STK4	13
GO:0042476	odontogenesis	15/2053	130/18722	0.458168924018055	0.661615774755314	SNX10/PERP/LAMB1/BSG/BMP7/LAMA5/TFAP2A/RHOA/RELT/HDAC2/ID3/TCIRG1/GLI3/SP6/FOXC1	15
GO:0006936	muscle contraction	39/2053	347/18722	0.460379150075588	0.664398758769796	CXCR4/FLNA/SLC8A1/DSP/PTAFR/DOCK4/RCSD1/CALD1/SOD1/C12orf57/ATP2B1/KCNQ1/TNNI2/NR4A1/DSG2/GJA1/CAMK2D/KCNE3/ASPH/ALDOA/GJA5/SULF2/SPHK1/DSC2/RHOA/CALM2/TPM3/MYL6/RGS2/SLC9A1/DLG1/DMD/GAA/CHRNB1/PABPN1/AKAP9/SMAD5/TBX3/HOMER1	39
GO:0000054	ribosomal subunit export from nucleus	2/2053	14/18722	0.464193266127164	0.664398758769796	RAN/NPM1	2
GO:0000212	meiotic spindle organization	2/2053	14/18722	0.464193266127164	0.664398758769796	ASPM/FBXO5	2
GO:0006241	CTP biosynthetic process	2/2053	14/18722	0.464193266127164	0.664398758769796	NME4/NME1	2
GO:0007638	mechanosensory behavior	2/2053	14/18722	0.464193266127164	0.664398758769796	CNTNAP2/SLC1A3	2
GO:0010838	positive regulation of keratinocyte proliferation	2/2053	14/18722	0.464193266127164	0.664398758769796	NOTCH2/MDK	2
GO:0018158	protein oxidation	2/2053	14/18722	0.464193266127164	0.664398758769796	GPX1/PRDX3	2
GO:0030213	hyaluronan biosynthetic process	2/2053	14/18722	0.464193266127164	0.664398758769796	TGFB1/IL1B	2
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	2/2053	14/18722	0.464193266127164	0.664398758769796	HHEX/EPN2	2
GO:0031054	pre-miRNA processing	2/2053	14/18722	0.464193266127164	0.664398758769796	LIN28B/AGO2	2
GO:0032966	negative regulation of collagen biosynthetic process	2/2053	14/18722	0.464193266127164	0.664398758769796	CIITA/RAP1A	2
GO:0033750	ribosome localization	2/2053	14/18722	0.464193266127164	0.664398758769796	RAN/NPM1	2
GO:0035641	locomotory exploration behavior	2/2053	14/18722	0.464193266127164	0.664398758769796	LRRK2/DPP4	2
GO:0036151	phosphatidylcholine acyl-chain remodeling	2/2053	14/18722	0.464193266127164	0.664398758769796	LPCAT2/DBI	2
GO:0038183	bile acid signaling pathway	2/2053	14/18722	0.464193266127164	0.664398758769796	GPBAR1/VDR	2
GO:0042921	glucocorticoid receptor signaling pathway	2/2053	14/18722	0.464193266127164	0.664398758769796	CALR/PHB	2
GO:0043249	erythrocyte maturation	2/2053	14/18722	0.464193266127164	0.664398758769796	KLF2/FAM210B	2
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	2/2053	14/18722	0.464193266127164	0.664398758769796	PMAIP1/EEF1E1	2
GO:0044764	multi-organism cellular process	2/2053	14/18722	0.464193266127164	0.664398758769796	CTSL/SIGLEC1	2
GO:0045023	G0 to G1 transition	2/2053	14/18722	0.464193266127164	0.664398758769796	CHEK1/FOXO4	2
GO:0045989	positive regulation of striated muscle contraction	2/2053	14/18722	0.464193266127164	0.664398758769796	KCNQ1/RGS2	2
GO:0046325	negative regulation of glucose import	2/2053	14/18722	0.464193266127164	0.664398758769796	TNF/PEA15	2
GO:0051589	negative regulation of neurotransmitter transport	2/2053	14/18722	0.464193266127164	0.664398758769796	PNKD/RAP1A	2
GO:0060354	negative regulation of cell adhesion molecule production	2/2053	14/18722	0.464193266127164	0.664398758769796	NOTCH1/CXCL8	2
GO:0060911	cardiac cell fate commitment	2/2053	14/18722	0.464193266127164	0.664398758769796	ISL1/TBX3	2
GO:0070942	neutrophil mediated cytotoxicity	2/2053	14/18722	0.464193266127164	0.664398758769796	TREM1/MYD88	2
GO:0071285	cellular response to lithium ion	2/2053	14/18722	0.464193266127164	0.664398758769796	CDH1/CALR	2
GO:0071415	cellular response to purine-containing compound	2/2053	14/18722	0.464193266127164	0.664398758769796	SLC8A1/TRPM2	2
GO:0072540	T-helper 17 cell lineage commitment	2/2053	14/18722	0.464193266127164	0.664398758769796	IL6R/STAT3	2
GO:0086103	G protein-coupled receptor signaling pathway involved in heart process	2/2053	14/18722	0.464193266127164	0.664398758769796	GNAI2/RGS2	2
GO:0090239	regulation of histone H4 acetylation	2/2053	14/18722	0.464193266127164	0.664398758769796	SPI1/BRCA1	2
GO:0090308	regulation of DNA methylation-dependent heterochromatin assembly	2/2053	14/18722	0.464193266127164	0.664398758769796	DNMT1/TRIM28	2
GO:0099188	postsynaptic cytoskeleton organization	2/2053	14/18722	0.464193266127164	0.664398758769796	ACTB/WASF2	2
GO:1901857	positive regulation of cellular respiration	2/2053	14/18722	0.464193266127164	0.664398758769796	PARK7/VCP	2
GO:1903894	regulation of IRE1-mediated unfolded protein response	2/2053	14/18722	0.464193266127164	0.664398758769796	HSPA5/DNAJB9	2
GO:1905065	positive regulation of vascular associated smooth muscle cell differentiation	2/2053	14/18722	0.464193266127164	0.664398758769796	SOD2/ENG	2
GO:2001140	positive regulation of phospholipid transport	2/2053	14/18722	0.464193266127164	0.664398758769796	DBI/TRIAP1	2
GO:0003323	type B pancreatic cell development	3/2053	23/18722	0.469621187053907	0.669276943591934	RHEB/CDK6/BAD	3
GO:0006622	protein targeting to lysosome	3/2053	23/18722	0.469621187053907	0.669276943591934	LAPTM5/SORL1/HSPA8	3
GO:0021871	forebrain regionalization	3/2053	23/18722	0.469621187053907	0.669276943591934	ADGRG1/TRA2B/GLI3	3
GO:0030194	positive regulation of blood coagulation	3/2053	23/18722	0.469621187053907	0.669276943591934	PRDX2/CD36/HPSE	3
GO:0030539	male genitalia development	3/2053	23/18722	0.469621187053907	0.669276943591934	DHCR24/LGR4/TBX3	3
GO:0035812	renal sodium excretion	3/2053	23/18722	0.469621187053907	0.669276943591934	COMT/GNAI2/ATP6V1B1	3
GO:0035929	steroid hormone secretion	3/2053	23/18722	0.469621187053907	0.669276943591934	RETN/KCNQ1/C1QTNF1	3
GO:0045723	positive regulation of fatty acid biosynthetic process	3/2053	23/18722	0.469621187053907	0.669276943591934	CD74/IL1B/MID1IP1	3
GO:0045724	positive regulation of cilium assembly	3/2053	23/18722	0.469621187053907	0.669276943591934	CCDC88A/ATMIN/CCP110	3
GO:0045932	negative regulation of muscle contraction	3/2053	23/18722	0.469621187053907	0.669276943591934	DOCK4/SOD1/RGS2	3
GO:0060547	negative regulation of necrotic cell death	3/2053	23/18722	0.469621187053907	0.669276943591934	BIRC3/SLC25A4/ARHGEF2	3
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	3/2053	23/18722	0.469621187053907	0.669276943591934	HAMP/PARP2/RGS2	3
GO:0071218	cellular response to misfolded protein	3/2053	23/18722	0.469621187053907	0.669276943591934	SDF2L1/VCP/DNAJB14	3
GO:0071636	positive regulation of transforming growth factor beta production	3/2053	23/18722	0.469621187053907	0.669276943591934	LGALS9/CD46/FERMT1	3
GO:0090335	regulation of brown fat cell differentiation	3/2053	23/18722	0.469621187053907	0.669276943591934	METRNL/BMP7/MAPK14	3
GO:1900048	positive regulation of hemostasis	3/2053	23/18722	0.469621187053907	0.669276943591934	PRDX2/CD36/HPSE	3
GO:1902410	mitotic cytokinetic process	3/2053	23/18722	0.469621187053907	0.669276943591934	RHOA/KIF20B/CHMP4C	3
GO:0072329	monocarboxylic acid catabolic process	14/2053	122/18722	0.470909270240091	0.669276943591934	SLC27A2/ECI1/ECHS1/ACADVL/ECHDC2/ETFB/NUDT8/HADH/ETFA/ACAT2/ABHD2/ECI2/SLC25A17/ECH1	14
GO:0003180	aortic valve morphogenesis	4/2053	32/18722	0.471722448771011	0.669276943591934	TGFB1/NOTCH1/GATA3/EFNA1	4
GO:0003338	metanephros morphogenesis	4/2053	32/18722	0.471722448771011	0.669276943591934	STAT1/FRAS1/LGR4/BASP1	4
GO:0006026	aminoglycan catabolic process	4/2053	32/18722	0.471722448771011	0.669276943591934	CD44/TGFB1/FUCA1/IDS	4
GO:0030431	sleep	4/2053	32/18722	0.471722448771011	0.669276943591934	FOS/SLC29A1/ADRB1/IL18	4
GO:0032196	transposition	4/2053	32/18722	0.471722448771011	0.669276943591934	APOBEC3A/L1TD1/APOBEC3G/APOBEC3C	4
GO:0045684	positive regulation of epidermis development	4/2053	32/18722	0.471722448771011	0.669276943591934	NOTCH1/VDR/FOXC1/KRT10	4
GO:0046475	glycerophospholipid catabolic process	4/2053	32/18722	0.471722448771011	0.669276943591934	GPCPD1/PLA2G7/APOC1/PRDX6	4
GO:0060323	head morphogenesis	4/2053	32/18722	0.471722448771011	0.669276943591934	RRAS/ARID5B/PLEKHA1/CRISPLD1	4
GO:0071875	adrenergic receptor signaling pathway	4/2053	32/18722	0.471722448771011	0.669276943591934	KCNQ1/GNAI2/ADRB1/RGS2	4
GO:1901185	negative regulation of ERBB signaling pathway	4/2053	32/18722	0.471722448771011	0.669276943591934	EGFR/MVP/VPS25/PTPN3	4
GO:1901889	negative regulation of cell junction assembly	4/2053	32/18722	0.471722448771011	0.669276943591934	TLR2/TNF/IL1B/CORO1C	4
GO:1903955	positive regulation of protein targeting to mitochondrion	4/2053	32/18722	0.471722448771011	0.669276943591934	RAC2/PDCD5/SAE1/HUWE1	4
GO:2000191	regulation of fatty acid transport	4/2053	32/18722	0.471722448771011	0.669276943591934	IL1B/SYK/FIS1/PTGES	4
GO:0006892	post-Golgi vesicle-mediated transport	12/2053	104/18722	0.471723008038411	0.669276943591934	LAPTM5/SORL1/VAMP5/KRT18/CSK/GOLGA4/ANK3/SPTBN1/GOPC/VPS13C/COMMD1/MYO5A	12
GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	12/2053	104/18722	0.471723008038411	0.669276943591934	FPR1/C5AR1/FPR3/C3AR1/GPR65/LPAR6/TGM2/GNA15/CX3CR1/P2RY11/GNA11/HOMER1	12
GO:0045921	positive regulation of exocytosis	10/2053	86/18722	0.472441312313583	0.669276943591934	ITGB2/HLA-F/FGR/ITGAM/PTAFR/SYK/SYT7/SNX4/SDCBP/RAB3D	10
GO:0070296	sarcoplasmic reticulum calcium ion transport	5/2053	41/18722	0.472638393088844	0.669276943591934	CCL3/SLC8A1/CAMK2D/CALM2/DMD	5
GO:1902116	negative regulation of organelle assembly	5/2053	41/18722	0.472638393088844	0.669276943591934	LRRK2/BRCA1/YAP1/CCP110/ODF2L	5
GO:0000380	alternative mRNA splicing, via spliceosome	9/2053	77/18722	0.472735074072048	0.669276943591934	CELF2/SRSF2/MBNL3/HNRNPA1/MAGOH/RBM17/MBNL1/RBMX/TRA2B	9
GO:0031016	pancreas development	9/2053	77/18722	0.472735074072048	0.669276943591934	WLS/MET/IL6R/ISL1/RHEB/SOX4/CDK6/BAD/MEIS2	9
GO:0140056	organelle localization by membrane tethering	9/2053	77/18722	0.472735074072048	0.669276943591934	PLEK/STXBP2/STX11/VMP1/RALB/RAB3IP/RAB3D/STX10/STX6	9
GO:0042987	amyloid precursor protein catabolic process	8/2053	68/18722	0.472956464180082	0.669276943591934	LYN/SORL1/TNF/DHCR24/EFNA1/FKBP1A/IFNGR1/PICALM	8
GO:0051148	negative regulation of muscle cell differentiation	8/2053	68/18722	0.472956464180082	0.669276943591934	DNMT1/NOTCH1/EZH2/FOXO4/RGS2/ID2/BHLHE41/YBX1	8
GO:0007140	male meiotic nuclear division	6/2053	50/18722	0.473001872981173	0.669276943591934	UBB/RAD51C/BRCA2/ING2/FIGNL1/FANCA	6
GO:0060425	lung morphogenesis	6/2053	50/18722	0.473001872981173	0.669276943591934	TNF/CTSH/CTSZ/DAG1/DLG5/YAP1	6
GO:0071709	membrane assembly	6/2053	50/18722	0.473001872981173	0.669276943591934	EMP2/S100A10/ANK3/SPTBN1/UBXN2A/PICALM	6
GO:1900047	negative regulation of hemostasis	6/2053	50/18722	0.473001872981173	0.669276943591934	CD9/SH2B3/C1QTNF1/UBASH3B/PDGFA/SERPING1	6
GO:1904036	negative regulation of epithelial cell apoptotic process	6/2053	50/18722	0.473001872981173	0.669276943591934	TNFAIP3/HMOX1/ICAM1/GATA3/YAP1/MDK	6
GO:0033013	tetrapyrrole metabolic process	7/2053	59/18722	0.473067252962232	0.669276943591934	TSPO/HMOX1/EIF2AK1/MMAB/MTR/CD320/ALAD	7
GO:0048278	vesicle docking	7/2053	59/18722	0.473067252962232	0.669276943591934	PLEK/STXBP2/STX11/RALB/RAB3D/STX10/STX6	7
GO:0051055	negative regulation of lipid biosynthetic process	7/2053	59/18722	0.473067252962232	0.669276943591934	SOD1/ORMDL1/BRCA1/ACADVL/APOC1/SPHK1/PDGFA	7
GO:0045165	cell fate commitment	29/2053	258/18722	0.473193897694763	0.669298299426821	MEF2C/KLF4/CTSL/PRKDC/STAT6/RARA/ITGB1/NOTCH1/LMO4/NR2F2/IL6R/SPN/RTF1/MCL1/EPAS1/NRP1/ISL1/RHOA/NOTCH2/STAT3/GATA3/ESRP1/ARHGEF2/GLI3/ID2/KDM6B/SMAD5/TBX3/PPARG	29
GO:0043010	camera-type eye development	36/2053	322/18722	0.477316350704732	0.674970092912654	VIM/EFEMP1/SKIL/KLF4/FBN2/VEGFA/FBN1/SERPINF1/RRM1/PFDN5/TENM3/RARA/C12orf57/BMP7/ATP2B1/FLT1/FAT1/TFAP2A/NRP1/NOTCH2/HDAC2/AHI1/GATA3/CDK4/LRP5/COL4A1/HMGN1/OBSL1/IMPDH2/DLG1/TCIRG1/GLI3/FOXC1/FJX1/PTN/ACTL6A	36
GO:0016571	histone methylation	16/2053	141/18722	0.481928517081624	0.681331551010779	DNMT1/RTF1/BRCA1/EZH2/SUZ12/SMYD2/GATA3/BRD4/KMT5A/KMT2E/DPY30/RIF1/NTMT1/LMNA/FBL/PWP1	16
GO:1901800	positive regulation of proteasomal protein catabolic process	13/2053	114/18722	0.484536551472962	0.684857316569557	LRRK2/PLK3/TREM2/PSMC3/TRIB1/PSMC1/BAG2/PSMC2/TMTC3/HSPA1A/VCP/PLK2/GABARAP	13
GO:0072330	monocarboxylic acid biosynthetic process	24/2053	214/18722	0.485854125654195	0.686557878927266	CD74/ALOX5/HACD3/IL1B/GSTP1/SDS/SLC27A2/ACSS1/TECR/TBXAS1/PDK4/BRCA1/ACADVL/DEGS1/APOC1/FABP5/NDUFAB1/MID1IP1/ABHD2/PARK7/PTGES/MGLL/HACD4/PRKAG2	24
GO:0006637	acyl-CoA metabolic process	11/2053	96/18722	0.486501476686143	0.687148978370258	KYNU/MPC2/ACSS1/TECR/PDK4/PPT1/NUDT8/SLC25A1/ACSL4/PMVK/PDHA1	11
GO:0035383	thioester metabolic process	11/2053	96/18722	0.486501476686143	0.687148978370258	KYNU/MPC2/ACSS1/TECR/PDK4/PPT1/NUDT8/SLC25A1/ACSL4/PMVK/PDHA1	11
GO:0044070	regulation of anion transport	10/2053	87/18722	0.487574514846647	0.688340491548207	TCAF1/IL1B/PTAFR/CEBPB/SYK/ITGB1/GOPC/RGS2/GABRE/PTGES	10
GO:0061014	positive regulation of mRNA catabolic process	10/2053	87/18722	0.487574514846647	0.688340491548207	ZFP36/ZFP36L2/PABPC1/ZFP36L1/HNRNPR/BTG2/EXOSC8/HNRNPD/KHSRP/AGO2	10
GO:0008306	associative learning	9/2053	78/18722	0.488723189912394	0.689313384925802	FOS/APP/ITGB1/PPT1/BTG2/TPBG/ACTR2/NRGN/MEIS2	9
GO:0019319	hexose biosynthetic process	9/2053	78/18722	0.488723189912394	0.689313384925802	FBP1/SDS/PGP/SLC35B4/AKR1B1/DDB1/SLC25A1/CHST15/ATF3	9
GO:0035050	embryonic heart tube development	9/2053	78/18722	0.488723189912394	0.689313384925802	MEF2C/ENG/NOTCH1/NOTCH2/AHI1/FOLR1/YAP1/FOXC1/TBX3	9
GO:0061045	negative regulation of wound healing	9/2053	78/18722	0.488723189912394	0.689313384925802	CD9/ALOX5/TNF/SH2B3/GJA1/C1QTNF1/UBASH3B/PDGFA/SERPING1	9
GO:0003143	embryonic heart tube morphogenesis	8/2053	69/18722	0.489963618467416	0.69057592454886	MEF2C/ENG/NOTCH1/NOTCH2/AHI1/FOLR1/YAP1/TBX3	8
GO:0031060	regulation of histone methylation	8/2053	69/18722	0.489963618467416	0.69057592454886	DNMT1/RTF1/BRCA1/GATA3/BRD4/KMT2E/RIF1/LMNA	8
GO:0051966	regulation of synaptic transmission, glutamatergic	8/2053	69/18722	0.489963618467416	0.69057592454886	MEF2C/EGFR/LRRK2/TNF/CCR2/GLUL/PTK2B/HOMER1	8
GO:0043271	negative regulation of ion transport	18/2053	160/18722	0.491509514311312	0.692429463692856	LILRB2/LILRB1/PTK2B/HAMP/ICAM1/CD33/CAMK2D/KCNE3/CALM2/C4orf3/ANK3/VDAC1/GOPC/YWHAE/RGS2/GABRE/COMMD1/PACSIN3	18
GO:0060402	calcium ion transport into cytosol	18/2053	160/18722	0.491509514311312	0.692429463692856	PTPRC/CORO1A/CCL3/CYBA/LYN/SLC8A1/CXCL10/PTPN6/PTK2B/TRPV2/P2RX7/CAMK2D/TRPM2/CALM2/MCOLN3/DMD/FKBP1A/UBASH3B	18
GO:0006636	unsaturated fatty acid biosynthetic process	6/2053	51/18722	0.492816740318182	0.69394518702396	CD74/IL1B/TBXAS1/DEGS1/FABP5/PTGES	6
GO:0048013	ephrin receptor signaling pathway	6/2053	51/18722	0.492816740318182	0.69394518702396	LYN/RASA1/EPHB4/EFNA1/YES1/PTK2	6
GO:0035025	positive regulation of Rho protein signal transduction	4/2053	33/18722	0.49645059469095	0.695746687462765	GPR65/LPAR6/ADGRG1/NET1	4
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	4/2053	33/18722	0.49645059469095	0.695746687462765	HMGB1/CDK4/ERCC1/ZNF451	4
GO:0099084	postsynaptic specialization organization	4/2053	33/18722	0.49645059469095	0.695746687462765	LILRB2/ABI3/ZDHHC12/DLG1	4
GO:0003181	atrioventricular valve morphogenesis	3/2053	24/18722	0.498743820987971	0.695746687462765	NOTCH1/SOX4/EFNA1	3
GO:0006817	phosphate ion transport	3/2053	24/18722	0.498743820987971	0.695746687462765	CEBPB/SLC25A3/SLC20A1	3
GO:0010226	response to lithium ion	3/2053	24/18722	0.498743820987971	0.695746687462765	CDH1/CALR/PTK2B	3
GO:0016048	detection of temperature stimulus	3/2053	24/18722	0.498743820987971	0.695746687462765	CXCR4/ARRB2/NR2F6	3
GO:0021801	cerebral cortex radial glia-guided migration	3/2053	24/18722	0.498743820987971	0.695746687462765	ADGRG1/LAMB1/GLI3	3
GO:0022030	telencephalon glial cell migration	3/2053	24/18722	0.498743820987971	0.695746687462765	ADGRG1/LAMB1/GLI3	3
GO:0031639	plasminogen activation	3/2053	24/18722	0.498743820987971	0.695746687462765	RUNX1/CTSZ/DHCR24	3
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	3/2053	24/18722	0.498743820987971	0.695746687462765	SULF2/GATA3/GPC1	3
GO:0050820	positive regulation of coagulation	3/2053	24/18722	0.498743820987971	0.695746687462765	PRDX2/CD36/HPSE	3
GO:0051156	glucose 6-phosphate metabolic process	3/2053	24/18722	0.498743820987971	0.695746687462765	HK3/HK2/RPIA	3
GO:0061162	establishment of monopolar cell polarity	3/2053	24/18722	0.498743820987971	0.695746687462765	MSN/FAT1/RHOA	3
GO:0070841	inclusion body assembly	3/2053	24/18722	0.498743820987971	0.695746687462765	SORL1/HSPA1A/VCP	3
GO:0030178	negative regulation of Wnt signaling pathway	19/2053	170/18722	0.50127841405701	0.695746687462765	PFDN5/NOTCH1/NOTUM/RNF43/TPBG/FERMT1/RNF213/ISL1/SIAH2/HMGXB4/TLE1/GLI3/STK4/MDK/CTNND1/ZNRF3/PTPRU/MAPK14/GPC3	19
GO:0000478	endonucleolytic cleavage involved in rRNA processing	2/2053	15/18722	0.501401446098166	0.695746687462765	RPS21/BMS1	2
GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2/2053	15/18722	0.501401446098166	0.695746687462765	RPS21/BMS1	2
GO:0002836	positive regulation of response to tumor cell	2/2053	15/18722	0.501401446098166	0.695746687462765	HLA-DRB1/HSPD1	2
GO:0002839	positive regulation of immune response to tumor cell	2/2053	15/18722	0.501401446098166	0.695746687462765	HLA-DRB1/HSPD1	2
GO:0003356	regulation of cilium beat frequency	2/2053	15/18722	0.501401446098166	0.695746687462765	CATSPER1/CFAP20	2
GO:0007000	nucleolus organization	2/2053	15/18722	0.501401446098166	0.695746687462765	RPS19/SMARCA5	2
GO:0007216	G protein-coupled glutamate receptor signaling pathway	2/2053	15/18722	0.501401446098166	0.695746687462765	HOMER3/HOMER1	2
GO:0009209	pyrimidine ribonucleoside triphosphate biosynthetic process	2/2053	15/18722	0.501401446098166	0.695746687462765	NME4/NME1	2
GO:0010452	histone H3-K36 methylation	2/2053	15/18722	0.501401446098166	0.695746687462765	SMYD2/BRD4	2
GO:0010832	negative regulation of myotube differentiation	2/2053	15/18722	0.501401446098166	0.695746687462765	NOTCH1/BHLHE41	2
GO:0014841	skeletal muscle satellite cell proliferation	2/2053	15/18722	0.501401446098166	0.695746687462765	JAK2/STAT3	2
GO:0014857	regulation of skeletal muscle cell proliferation	2/2053	15/18722	0.501401446098166	0.695746687462765	JAK2/STAT3	2
GO:0032310	prostaglandin secretion	2/2053	15/18722	0.501401446098166	0.695746687462765	IL1B/PTGES	2
GO:0032328	alanine transport	2/2053	15/18722	0.501401446098166	0.695746687462765	SLC6A6/SLC3A2	2
GO:0032488	Cdc42 protein signal transduction	2/2053	15/18722	0.501401446098166	0.695746687462765	WAS/NRP1	2
GO:0032897	negative regulation of viral transcription	2/2053	15/18722	0.501401446098166	0.695746687462765	ZFP36/IFITM3	2
GO:0034310	primary alcohol catabolic process	2/2053	15/18722	0.501401446098166	0.695746687462765	ALDH2/SULT1A1	2
GO:0034638	phosphatidylcholine catabolic process	2/2053	15/18722	0.501401446098166	0.695746687462765	PLA2G7/APOC1	2
GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	2/2053	15/18722	0.501401446098166	0.695746687462765	FABP5/ASXL1	2
GO:0035435	phosphate ion transmembrane transport	2/2053	15/18722	0.501401446098166	0.695746687462765	SLC25A3/SLC20A1	2
GO:0036376	sodium ion export across plasma membrane	2/2053	15/18722	0.501401446098166	0.695746687462765	SLC8A1/SLC9A1	2
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	2/2053	15/18722	0.501401446098166	0.695746687462765	CD74/CD44	2
GO:0044406	adhesion of symbiont to host	2/2053	15/18722	0.501401446098166	0.695746687462765	HSP90AB1/ICAM1	2
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	2/2053	15/18722	0.501401446098166	0.695746687462765	ANAPC11/CDT1	2
GO:0046007	negative regulation of activated T cell proliferation	2/2053	15/18722	0.501401446098166	0.695746687462765	LGALS9/LILRB4	2
GO:0046834	lipid phosphorylation	2/2053	15/18722	0.501401446098166	0.695746687462765	SPHK1/DGKD	2
GO:0051775	response to redox state	2/2053	15/18722	0.501401446098166	0.695746687462765	ARHGDIB/ADH5	2
GO:0051938	L-glutamate import	2/2053	15/18722	0.501401446098166	0.695746687462765	ITGB1/SLC1A3	2
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	2/2053	15/18722	0.501401446098166	0.695746687462765	SORL1/LRRK2	2
GO:0060766	negative regulation of androgen receptor signaling pathway	2/2053	15/18722	0.501401446098166	0.695746687462765	NCOR2/PHB	2
GO:0070071	proton-transporting two-sector ATPase complex assembly	2/2053	15/18722	0.501401446098166	0.695746687462765	ATP6V1B1/ATPAF1	2
GO:0070131	positive regulation of mitochondrial translation	2/2053	15/18722	0.501401446098166	0.695746687462765	C1QBP/UQCC2	2
GO:0070831	basement membrane assembly	2/2053	15/18722	0.501401446098166	0.695746687462765	LAMB1/DAG1	2
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	2/2053	15/18722	0.501401446098166	0.695746687462765	SORL1/TMEM30B	2
GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus	2/2053	15/18722	0.501401446098166	0.695746687462765	RAN/NPM1	2
GO:0071599	otic vesicle development	2/2053	15/18722	0.501401446098166	0.695746687462765	AHI1/GATA3	2
GO:0071871	response to epinephrine	2/2053	15/18722	0.501401446098166	0.695746687462765	KCNQ1/SLC9A1	2
GO:0098712	L-glutamate import across plasma membrane	2/2053	15/18722	0.501401446098166	0.695746687462765	ITGB1/SLC1A3	2
GO:0099170	postsynaptic modulation of chemical synaptic transmission	2/2053	15/18722	0.501401446098166	0.695746687462765	CDH1/NRGN	2
GO:1901741	positive regulation of myoblast fusion	2/2053	15/18722	0.501401446098166	0.695746687462765	CD53/MAPK14	2
GO:1901836	regulation of transcription of nucleolar large rRNA by RNA polymerase I	2/2053	15/18722	0.501401446098166	0.695746687462765	NCL/PWP1	2
GO:1901970	positive regulation of mitotic sister chromatid separation	2/2053	15/18722	0.501401446098166	0.695746687462765	ANAPC11/CDT1	2
GO:1903727	positive regulation of phospholipid metabolic process	2/2053	15/18722	0.501401446098166	0.695746687462765	CHP1/STOML2	2
GO:1904424	regulation of GTP binding	2/2053	15/18722	0.501401446098166	0.695746687462765	STMN1/MET	2
GO:1904889	regulation of excitatory synapse assembly	2/2053	15/18722	0.501401446098166	0.695746687462765	ABI3/SEMA4A	2
GO:1905146	lysosomal protein catabolic process	2/2053	15/18722	0.501401446098166	0.695746687462765	LRP2/TPP1	2
GO:2001138	regulation of phospholipid transport	2/2053	15/18722	0.501401446098166	0.695746687462765	DBI/TRIAP1	2
GO:0006023	aminoglycan biosynthetic process	9/2053	79/18722	0.504585368775053	0.699841010783707	TGFB1/IL1B/CHPF/HS3ST1/CHST15/CHST14/DSE/B3GAT3/HS6ST2	9
GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	9/2053	79/18722	0.504585368775053	0.699841010783707	S100A12/RNASE6/CXCL10/S100A9/HMGN2/CXCL8/RPS19/DEFB1/GAPDH	9
GO:0006865	amino acid transport	16/2053	143/18722	0.505545249499377	0.701010283567428	SLC11A1/SLC7A7/SLC38A1/ITGB1/LRRC8C/GJA1/SLC6A6/SLC1A5/SFXN3/SFXN1/RGS2/SLC7A6/SLC38A9/SLC38A6/SLC3A2/SLC1A3	16
GO:0006066	alcohol metabolic process	39/2053	353/18722	0.505716465346878	0.701085672846873	PLEK/ALDH2/NPC2/ISYNA1/APP/PGP/PTAFR/APOBR/SOD1/ACSS1/AKR7A2/FDPS/PTK2B/DHCR24/DHFR/ADH5/ACADVL/IDH2/SULT1A1/AKR1B1/ALDH1A1/SPHK1/SQLE/FDFT1/LRP5/PLPP3/PMVK/IMPA2/IDH1/EBP/NUDT4/PARK7/GCH1/QDPR/LIMA1/GK/HDLBP/DPM2/LDLRAP1	39
GO:0008277	regulation of G protein-coupled receptor signaling pathway	15/2053	134/18722	0.507155767419966	0.70291859656267	PLEK/STMN1/RGS18/ARRB2/C3/RGS1/MET/RGS10/CXCL8/GNAI2/PHB/RGS2/NMT1/MGLL/DYNLT1	15
GO:0043966	histone H3 acetylation	7/2053	61/18722	0.509372985186475	0.705665645605829	SPI1/BRCA1/CHEK1/GATA3/BRCA2/POLE3/ZNF451	7
GO:0060998	regulation of dendritic spine development	7/2053	61/18722	0.509372985186475	0.705665645605829	MEF2C/CAMK1/ACTR2/HDAC2/DLG5/EFNA1/PLK2	7
GO:0030326	embryonic limb morphogenesis	13/2053	116/18722	0.510754830101354	0.706927100486304	FBN2/BMP7/NOTCH1/TFAP2A/FRAS1/NOTCH2/HDAC2/PBX1/LRP5/MBNL1/GLI3/TBX3/GPC3	13
GO:0030518	intracellular steroid hormone receptor signaling pathway	13/2053	116/18722	0.510754830101354	0.706927100486304	JAK2/PARP1/CALR/BRCA1/PHB2/ISL1/RHOA/NCOR2/YAP1/PHB/PARK7/SKP2/PKN1	13
GO:0033559	unsaturated fatty acid metabolic process	13/2053	116/18722	0.510754830101354	0.706927100486304	CD74/GPX1/ALOX5/IL1B/GSTP1/TBXAS1/DEGS1/HPGD/AKR1B1/FABP5/ATP6V1B1/PTGES/MGLL	13
GO:0035113	embryonic appendage morphogenesis	13/2053	116/18722	0.510754830101354	0.706927100486304	FBN2/BMP7/NOTCH1/TFAP2A/FRAS1/NOTCH2/HDAC2/PBX1/LRP5/MBNL1/GLI3/TBX3/GPC3	13
GO:0046890	regulation of lipid biosynthetic process	19/2053	171/18722	0.512046613862754	0.70855158744846	TSPO/CD74/TNF/IL1B/C3/SOD1/PDK4/ORMDL1/BRCA1/ACADVL/CHP1/APOC1/SPHK1/FABP5/SF1/CDK4/MID1IP1/IDH1/PDGFA	19
GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	6/2053	52/18722	0.512376858060801	0.708681684731398	ERGIC2/TAPBP/ERGIC3/PLPP3/PITPNB/KDELR2	6
GO:0072132	mesenchyme morphogenesis	6/2053	52/18722	0.512376858060801	0.708681684731398	BMP7/ENG/NOTCH1/ISL1/FOXC1/TBX3	6
GO:0007338	single fertilization	17/2053	153/18722	0.51541207905922	0.712715481529227	CD9/LHFPL2/CD46/CDK1/SPESP1/ALDOA/SLIRP/TCP1/FOLR1/SNU13/CCT2/PITHD1/ABHD2/PARK7/CCT4/CCT8/HEXB	17
GO:0030517	negative regulation of axon extension	5/2053	43/18722	0.516024537781361	0.713397978499578	SEMA4A/ARHGAP4/SEMA6A/NRP1/SEMA6D	5
GO:0043588	skin development	29/2053	263/18722	0.516884947844571	0.714422871934444	TXNIP/ZFP36/EGFR/STMN1/ITGA6/TNF/DSP/MET/CLDN4/LAMA5/NOTCH1/ITGB4/ZFP36L1/HPSE/DHCR24/LGR5/LSR/FERMT1/FRAS1/HDAC2/VDR/CSTA/LGR4/YAP1/PALLD/STK4/FOXC1/KRT10/PDGFA	29
GO:0031644	regulation of nervous system process	16/2053	144/18722	0.517264695000558	0.714783088439279	CCL3/TYMP/TNFRSF1B/LRRK2/APP/PTAFR/DAG1/ITGAX/PTK2B/COMT/FABP5/PARD3/SLC9A1/MGLL/AKAP9/HOMER1	16
GO:0000038	very long-chain fatty acid metabolic process	4/2053	34/18722	0.520669332072221	0.717669651374529	HACD3/SLC27A2/TECR/HACD4	4
GO:0009649	entrainment of circadian clock	4/2053	34/18722	0.520669332072221	0.717669651374529	NR2F6/BHLHE40/GNA11/ID2	4
GO:0010614	negative regulation of cardiac muscle hypertrophy	4/2053	34/18722	0.520669332072221	0.717669651374529	TNFRSF1B/NOTCH1/RGS2/LMNA	4
GO:0014072	response to isoquinoline alkaloid	4/2053	34/18722	0.520669332072221	0.717669651374529	AIF1/CXCR4/FOSB/PEA15	4
GO:0019076	viral release from host cell	4/2053	34/18722	0.520669332072221	0.717669651374529	PPIA/DDB1/CHMP4C/TRIM28	4
GO:0035890	exit from host	4/2053	34/18722	0.520669332072221	0.717669651374529	PPIA/DDB1/CHMP4C/TRIM28	4
GO:0035891	exit from host cell	4/2053	34/18722	0.520669332072221	0.717669651374529	PPIA/DDB1/CHMP4C/TRIM28	4
GO:0043278	response to morphine	4/2053	34/18722	0.520669332072221	0.717669651374529	AIF1/CXCR4/FOSB/PEA15	4
GO:0086019	cell-cell signaling involved in cardiac conduction	4/2053	34/18722	0.520669332072221	0.717669651374529	FLNA/KCNQ1/GJA1/GJA5	4
GO:0090075	relaxation of muscle	4/2053	34/18722	0.520669332072221	0.717669651374529	SLC8A1/SOD1/CAMK2D/RGS2	4
GO:2000780	negative regulation of double-strand break repair	4/2053	34/18722	0.520669332072221	0.717669651374529	RMI2/MAGEF1/RIF1/POLQ	4
GO:0016236	macroautophagy	32/2053	291/18722	0.521414355532037	0.718531495910019	LRRK2/HMOX1/QSOX1/SLC25A5/VMP1/BNIP3L/PHB2/ATP6V1C2/RHEB/SLC25A4/RALB/CAPNS1/VDAC1/VPS13C/SCOC/UBXN2A/ATP6V1B1/EI24/TCIRG1/BNIP3/ATP6V1B2/ATG16L2/CHMP4C/VPS25/VCP/GABARAP/HUWE1/CAPN1/ATP6V0E1/TMEM41B/WIPI2/GAPDH	32
GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	30/2053	273/18722	0.524117779665863	0.722091085647573	ITGB2/FXYD5/PECAM1/CD84/ITGAL/KLF4/MBP/ITGAM/CDH1/MYADM/IL1RN/CADM1/BSG/TENM3/CLDN4/JAML/ITGB1/ALCAM/CLDN7/DSG2/ICAM1/DSC3/FAT1/DSC2/PTPRF/OBSL1/SELL/PALLD/CLSTN1/MAPK14	30
GO:0021846	cell proliferation in forebrain	3/2053	25/18722	0.527030771059498	0.722855058233684	RRM1/GLI3/NUMB	3
GO:0033233	regulation of protein sumoylation	3/2053	25/18722	0.527030771059498	0.722855058233684	GNL3/SAE1/PARK7	3
GO:0034389	lipid droplet organization	3/2053	25/18722	0.527030771059498	0.722855058233684	PPIA/SQLE/CDS1	3
GO:0050927	positive regulation of positive chemotaxis	3/2053	25/18722	0.527030771059498	0.722855058233684	VEGFA/IL16/CXCL8	3
GO:0050951	sensory perception of temperature stimulus	3/2053	25/18722	0.527030771059498	0.722855058233684	CXCR4/ARRB2/NR2F6	3
GO:0051291	protein heterooligomerization	3/2053	25/18722	0.527030771059498	0.722855058233684	RRM1/RRM2/KRT10	3
GO:0051307	meiotic chromosome separation	3/2053	25/18722	0.527030771059498	0.722855058233684	TOP2A/TTK/TOP2B	3
GO:0051450	myoblast proliferation	3/2053	25/18722	0.527030771059498	0.722855058233684	GPX1/MALAT1/MEIS2	3
GO:0051788	response to misfolded protein	3/2053	25/18722	0.527030771059498	0.722855058233684	SDF2L1/VCP/DNAJB14	3
GO:0060074	synapse maturation	3/2053	25/18722	0.527030771059498	0.722855058233684	CX3CR1/PFN1/CLSTN1	3
GO:0061339	establishment or maintenance of monopolar cell polarity	3/2053	25/18722	0.527030771059498	0.722855058233684	MSN/FAT1/RHOA	3
GO:0062009	secondary palate development	3/2053	25/18722	0.527030771059498	0.722855058233684	DLG1/TGFBR3/ITGB8	3
GO:0062149	detection of stimulus involved in sensory perception of pain	3/2053	25/18722	0.527030771059498	0.722855058233684	CXCR4/ARRB2/NR2F6	3
GO:0072202	cell differentiation involved in metanephros development	3/2053	25/18722	0.527030771059498	0.722855058233684	STAT1/LGR4/YAP1	3
GO:0072207	metanephric epithelium development	3/2053	25/18722	0.527030771059498	0.722855058233684	STAT1/LGR4/YAP1	3
GO:0098703	calcium ion import across plasma membrane	3/2053	25/18722	0.527030771059498	0.722855058233684	SLC8A1/TRPV2/TRPM2	3
GO:1903792	negative regulation of anion transport	3/2053	25/18722	0.527030771059498	0.722855058233684	GOPC/RGS2/GABRE	3
GO:1905563	negative regulation of vascular endothelial cell proliferation	3/2053	25/18722	0.527030771059498	0.722855058233684	MEF2C/FLT1/PPARG	3
GO:2000316	regulation of T-helper 17 type immune response	3/2053	25/18722	0.527030771059498	0.722855058233684	CLEC7A/IL27RA/NFKBIZ	3
GO:0046148	pigment biosynthetic process	7/2053	62/18722	0.527202289138433	0.722855058233684	TSPO/ZEB2/PAICS/GMPS/SHMT1/PPAT/ALAD	7
GO:0060113	inner ear receptor cell differentiation	7/2053	62/18722	0.527202289138433	0.722855058233684	SOD1/NOTCH1/KCNQ1/MCOLN3/ESRP1/TRIOBP/MYO7A	7
GO:0001541	ovarian follicle development	6/2053	53/18722	0.531645097626208	0.72828095565234	VEGFA/CEBPB/ARRB2/SOD1/ICAM1/FOXC1	6
GO:0016925	protein sumoylation	6/2053	53/18722	0.531645097626208	0.72828095565234	CBX4/GNL3/SAE1/PARK7/ZNF451/TRIM28	6
GO:0033059	cellular pigmentation	6/2053	53/18722	0.531645097626208	0.72828095565234	ZEB2/RAB32/LYST/CD63/MYO5A/MYO7A	6
GO:0043113	receptor clustering	6/2053	53/18722	0.531645097626208	0.72828095565234	ITGB2/FLNA/ITGAL/ITGA4/DLG1/PTN	6
GO:0048477	oogenesis	10/2053	90/18722	0.532273065024226	0.728808395742892	PTK2B/LGR5/ASPM/FBXO5/RPS6/BRCA2/ERCC1/MDK/PTN/HEXB	10
GO:0099175	regulation of postsynapse organization	10/2053	90/18722	0.532273065024226	0.728808395742892	SRGN/LILRB2/ABI3/LRRK2/NRP2/HSPA8/ACTR2/EFNA1/CFL1/HOMER1	10
GO:0016042	lipid catabolic process	35/2053	320/18722	0.533442898139361	0.729822451866571	SORL1/SPP1/TNF/AOAH/IL1B/SLC27A2/GPCPD1/ECI1/PLCB2/ECHS1/PLA2G7/ACADVL/HINT2/PPT1/ECHDC2/ETFB/NUDT8/APOC1/SPHK1/FUCA1/HADH/CDK4/PRDX6/LIPA/HSD17B11/ETFA/ACAT2/ABHD2/IDH1/ECI2/STS/MGLL/SLC25A17/HEXB/ECH1	35
GO:0006911	phagocytosis, engulfment	14/2053	127/18722	0.533826080866253	0.729822451866571	AIF1/ITGB2/FCGR1A/MSR1/NCKAP1L/CD300A/RAC2/ITGAM/CD36/C3/TREM2/ARHGAP25/MARCO/RHOG	14
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	2/2053	16/18722	0.536896530764544	0.729822451866571	ENG/NOTCH1	2
GO:0006828	manganese ion transport	2/2053	16/18722	0.536896530764544	0.729822451866571	SLC11A1/TRPM2	2
GO:0007635	chemosensory behavior	2/2053	16/18722	0.536896530764544	0.729822451866571	TPBG/ATP6V1B1	2
GO:0009048	dosage compensation by inactivation of X chromosome	2/2053	16/18722	0.536896530764544	0.729822451866571	XIST/BRCA1	2
GO:0010819	regulation of T cell chemotaxis	2/2053	16/18722	0.536896530764544	0.729822451866571	CCR2/CXCL10	2
GO:0019377	glycolipid catabolic process	2/2053	16/18722	0.536896530764544	0.729822451866571	FUCA1/HEXB	2
GO:0030540	female genitalia development	2/2053	16/18722	0.536896530764544	0.729822451866571	LRP2/TBX3	2
GO:0030575	nuclear body organization	2/2053	16/18722	0.536896530764544	0.729822451866571	SERBP1/SF1	2
GO:0032274	gonadotropin secretion	2/2053	16/18722	0.536896530764544	0.729822451866571	GJA1/TBX3	2
GO:0043923	positive regulation by host of viral transcription	2/2053	16/18722	0.536896530764544	0.729822451866571	NUCKS1/JUN	2
GO:0046036	CTP metabolic process	2/2053	16/18722	0.536896530764544	0.729822451866571	NME4/NME1	2
GO:0048311	mitochondrion distribution	2/2053	16/18722	0.536896530764544	0.729822451866571	LRRK2/MEF2A	2
GO:0048557	embryonic digestive tract morphogenesis	2/2053	16/18722	0.536896530764544	0.729822451866571	GLI3/ID2	2
GO:0050862	positive regulation of T cell receptor signaling pathway	2/2053	16/18722	0.536896530764544	0.729822451866571	RPS3/KCNN4	2
GO:0061548	ganglion development	2/2053	16/18722	0.536896530764544	0.729822451866571	NRP2/NRP1	2
GO:0070230	positive regulation of lymphocyte apoptotic process	2/2053	16/18722	0.536896530764544	0.729822451866571	LGALS9/ADAM8	2
GO:0070365	hepatocyte differentiation	2/2053	16/18722	0.536896530764544	0.729822451866571	KRT18/E2F7	2
GO:0098884	postsynaptic neurotransmitter receptor internalization	2/2053	16/18722	0.536896530764544	0.729822451866571	NUMB/AP2M1	2
GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential	2/2053	16/18722	0.536896530764544	0.729822451866571	KCNQ1/KCNE3	2
GO:0098969	neurotransmitter receptor transport to postsynaptic membrane	2/2053	16/18722	0.536896530764544	0.729822451866571	NSG1/CLSTN1	2
GO:0140239	postsynaptic endocytosis	2/2053	16/18722	0.536896530764544	0.729822451866571	NUMB/AP2M1	2
GO:1902101	positive regulation of metaphase/anaphase transition of cell cycle	2/2053	16/18722	0.536896530764544	0.729822451866571	ANAPC11/CDT1	2
GO:1902306	negative regulation of sodium ion transmembrane transport	2/2053	16/18722	0.536896530764544	0.729822451866571	CAMK2D/COMMD1	2
GO:1902931	negative regulation of alcohol biosynthetic process	2/2053	16/18722	0.536896530764544	0.729822451866571	PLEK/SOD1	2
GO:1905874	regulation of postsynaptic density organization	2/2053	16/18722	0.536896530764544	0.729822451866571	LILRB2/ABI3	2
GO:2000001	regulation of DNA damage checkpoint	2/2053	16/18722	0.536896530764544	0.729822451866571	RPA2/WDR76	2
GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	2/2053	16/18722	0.536896530764544	0.729822451866571	ZNRF3/GPC3	2
GO:0002792	negative regulation of peptide secretion	5/2053	44/18722	0.537149324573796	0.729822451866571	CD74/UCP2/KLF7/HADH/MIDN	5
GO:0030521	androgen receptor signaling pathway	5/2053	44/18722	0.537149324573796	0.729822451866571	RHOA/NCOR2/PHB/PARK7/PKN1	5
GO:0044058	regulation of digestive system process	5/2053	44/18722	0.537149324573796	0.729822451866571	TYMP/SGK1/KCNQ1/HAMP/EPB41	5
GO:0048806	genitalia development	5/2053	44/18722	0.537149324573796	0.729822451866571	LRP2/DHCR24/LGR4/DNAJC19/TBX3	5
GO:0060324	face development	5/2053	44/18722	0.537149324573796	0.729822451866571	RARA/RRAS/ARID5B/PLEKHA1/CRISPLD1	5
GO:0001707	mesoderm formation	8/2053	72/18722	0.539954897015991	0.73346827758568	KLF4/WLS/BMP7/ITGB1/ITGB4/GJA1/FOXC1/KDM6B	8
GO:0008203	cholesterol metabolic process	15/2053	137/18722	0.543198715731094	0.737707626615338	NPC2/APP/APOBR/SOD1/FDPS/DHCR24/ACADVL/SQLE/FDFT1/LRP5/PMVK/EBP/LIMA1/HDLBP/LDLRAP1	15
GO:0007020	microtubule nucleation	4/2053	35/18722	0.544319439479004	0.738060256920684	TPX2/HSPA1A/CENPJ/AKAP9	4
GO:0021955	central nervous system neuron axonogenesis	4/2053	35/18722	0.544319439479004	0.738060256920684	NR4A2/HSP90AA1/HSP90AB1/C12orf57	4
GO:0032205	negative regulation of telomere maintenance	4/2053	35/18722	0.544319439479004	0.738060256920684	PARP1/HNRNPA1/RAD50/ERCC1	4
GO:0046627	negative regulation of insulin receptor signaling pathway	4/2053	35/18722	0.544319439479004	0.738060256920684	IL1B/SOCS3/PRKCB/KANK1	4
GO:0050654	chondroitin sulfate proteoglycan metabolic process	4/2053	35/18722	0.544319439479004	0.738060256920684	CHPF/CHST15/DSE/B3GAT3	4
GO:0098810	neurotransmitter reuptake	4/2053	35/18722	0.544319439479004	0.738060256920684	ITGB1/SLC29A1/SLC6A4/PARK7	4
GO:1905207	regulation of cardiocyte differentiation	4/2053	35/18722	0.544319439479004	0.738060256920684	TGFB1/MEF2C/EGFR/ARRB2	4
GO:0001947	heart looping	7/2053	63/18722	0.544777502986989	0.738347643533304	MEF2C/ENG/NOTCH1/NOTCH2/AHI1/FOLR1/TBX3	7
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	7/2053	63/18722	0.544777502986989	0.738347643533304	LRRK2/CEBPB/ERP29/PMAIP1/PARK7/HSPA1A/PPP1R15A	7
GO:0042180	cellular ketone metabolic process	23/2053	211/18722	0.545118817125595	0.738643383639018	CD74/SLC7A7/IL1B/KYNU/AKR7A2/HSD17B1/PDK4/COMT/PNKD/BRCA1/ACADVL/AKR1B1/APOC1/FABP5/MID1IP1/NCOR2/COQ4/PARK7/NMT1/VKORC1/PRKAG2/PPARG/GLO1	23
GO:0033865	nucleoside bisphosphate metabolic process	14/2053	128/18722	0.546150336252628	0.739540062630505	KYNU/SLC26A2/MPC2/ACSS1/TECR/PDK4/PPT1/SULT1A1/NUDT8/SLC25A1/ACSL4/TPST2/PMVK/PDHA1	14
GO:0033875	ribonucleoside bisphosphate metabolic process	14/2053	128/18722	0.546150336252628	0.739540062630505	KYNU/SLC26A2/MPC2/ACSS1/TECR/PDK4/PPT1/SULT1A1/NUDT8/SLC25A1/ACSL4/TPST2/PMVK/PDHA1	14
GO:0034032	purine nucleoside bisphosphate metabolic process	14/2053	128/18722	0.546150336252628	0.739540062630505	KYNU/SLC26A2/MPC2/ACSS1/TECR/PDK4/PPT1/SULT1A1/NUDT8/SLC25A1/ACSL4/TPST2/PMVK/PDHA1	14
GO:0009913	epidermal cell differentiation	22/2053	202/18722	0.547272806929826	0.740892789164927	TXNIP/ZFP36/KLF4/DSP/SOD1/NOTCH1/ZFP36L1/KCNQ1/EZH2/KLF7/HDAC2/MCOLN3/VDR/CSTA/YAP1/ESRP1/PALLD/STK4/FOXC1/KRT10/TRIOBP/MYO7A	22
GO:0010906	regulation of glucose metabolic process	13/2053	119/18722	0.549375906079177	0.743572171548627	HMGB1/FBP1/PHLDA2/PGP/PDK4/SLC35B4/PMAIP1/DDB1/BAD/MIDN/C1QTNF1/LCMT1/INSR	13
GO:0030520	intracellular estrogen receptor signaling pathway	6/2053	54/18722	0.55058766723467	0.745044204647726	PARP1/BRCA1/PHB2/ISL1/YAP1/SKP2	6
GO:0046364	monosaccharide biosynthetic process	9/2053	82/18722	0.551203982284356	0.745710009854822	FBP1/SDS/PGP/SLC35B4/AKR1B1/DDB1/SLC25A1/CHST15/ATF3	9
GO:0001556	oocyte maturation	3/2053	26/18722	0.554406289210556	0.7465075707503	PTK2B/FBXO5/BRCA2	3
GO:0001573	ganglioside metabolic process	3/2053	26/18722	0.554406289210556	0.7465075707503	ST3GAL5/HEXB/ITGB8	3
GO:0006706	steroid catabolic process	3/2053	26/18722	0.554406289210556	0.7465075707503	SPP1/HSD17B11/STS	3
GO:0010875	positive regulation of cholesterol efflux	3/2053	26/18722	0.554406289210556	0.7465075707503	NFKBIA/TREM2/PPARG	3
GO:0021680	cerebellar Purkinje cell layer development	3/2053	26/18722	0.554406289210556	0.7465075707503	HSPA5/UQCRQ/RERE	3
GO:0033522	histone H2A ubiquitination	3/2053	26/18722	0.554406289210556	0.7465075707503	DDB1/DTX3L/RNF8	3
GO:0034643	establishment of mitochondrion localization, microtubule-mediated	3/2053	26/18722	0.554406289210556	0.7465075707503	UBB/ARMCX3/LRPPRC	3
GO:0042278	purine nucleoside metabolic process	3/2053	26/18722	0.554406289210556	0.7465075707503	MTAP/PNP/ADK	3
GO:0042634	regulation of hair cycle	3/2053	26/18722	0.554406289210556	0.7465075707503	TNF/HPSE/FERMT1	3
GO:0045026	plasma membrane fusion	3/2053	26/18722	0.554406289210556	0.7465075707503	CD9/SPESP1/FOLR1	3
GO:0047497	mitochondrion transport along microtubule	3/2053	26/18722	0.554406289210556	0.7465075707503	UBB/ARMCX3/LRPPRC	3
GO:0048668	collateral sprouting	3/2053	26/18722	0.554406289210556	0.7465075707503	SPP1/APP/COBL	3
GO:0050926	regulation of positive chemotaxis	3/2053	26/18722	0.554406289210556	0.7465075707503	VEGFA/IL16/CXCL8	3
GO:0060295	regulation of cilium movement involved in cell motility	3/2053	26/18722	0.554406289210556	0.7465075707503	CATSPER1/CFAP20/DEFB1	3
GO:0060544	regulation of necroptotic process	3/2053	26/18722	0.554406289210556	0.7465075707503	BIRC3/SLC25A4/ARHGEF2	3
GO:0097186	amelogenesis	3/2053	26/18722	0.554406289210556	0.7465075707503	PERP/RELT/TCIRG1	3
GO:1902019	regulation of cilium-dependent cell motility	3/2053	26/18722	0.554406289210556	0.7465075707503	CATSPER1/CFAP20/DEFB1	3
GO:1902656	calcium ion import into cytosol	3/2053	26/18722	0.554406289210556	0.7465075707503	SLC8A1/TRPV2/TRPM2	3
GO:1904861	excitatory synapse assembly	3/2053	26/18722	0.554406289210556	0.7465075707503	ABI3/SEMA4A/ZDHHC12	3
GO:1905063	regulation of vascular associated smooth muscle cell differentiation	3/2053	26/18722	0.554406289210556	0.7465075707503	SOD2/DNMT1/ENG	3
GO:2000050	regulation of non-canonical Wnt signaling pathway	3/2053	26/18722	0.554406289210556	0.7465075707503	RNF213/ZNRF3/GPC3	3
GO:0030258	lipid modification	23/2053	212/18722	0.554681493900705	0.746710559435547	ALOX5/SLC27A2/ECI1/ECHS1/PLA2G7/PDK4/ADH5/ACADVL/ECHDC2/ETFB/APOC1/SPHK1/HADH/PLPP3/ETFA/ACAT2/DGKD/INPP5D/ECI2/SLC25A17/ECH1/MAPK14/PRKAG2	23
GO:0051145	smooth muscle cell differentiation	8/2053	73/18722	0.556195473384804	0.748245031459378	MEF2C/SOD2/VEGFA/DNMT1/ENG/NOTCH1/FOXO4/TBX3	8
GO:0070988	demethylation	8/2053	73/18722	0.556195473384804	0.748245031459378	APOBEC3A/APOBEC3G/APOBEC3C/GATA3/KDM1B/APEX1/TRIM28/KDM6B	8
GO:0099518	vesicle cytoskeletal trafficking	8/2053	73/18722	0.556195473384804	0.748245031459378	MYO1F/MYO1G/MYO1C/FNBP1L/MYO5A/CCDC186/ACTN4/MYO7A	8
GO:0003197	endocardial cushion development	5/2053	45/18722	0.557838677009497	0.74961524346181	BMP7/ENG/NOTCH1/ISL1/TBX3	5
GO:0010824	regulation of centrosome duplication	5/2053	45/18722	0.557838677009497	0.74961524346181	NPM1/BRCA1/CENPJ/CHMP4C/PLK2	5
GO:0022602	ovulation cycle process	5/2053	45/18722	0.557838677009497	0.74961524346181	RETN/ARRB2/HSPA5/ADAMTS1/PLEKHA1	5
GO:0045933	positive regulation of muscle contraction	5/2053	45/18722	0.557838677009497	0.74961524346181	PTAFR/KCNQ1/SPHK1/RHOA/RGS2	5
GO:0046189	phenol-containing compound biosynthetic process	5/2053	45/18722	0.557838677009497	0.74961524346181	ZEB2/NR4A2/GATA3/PARK7/GCH1	5
GO:0006940	regulation of smooth muscle contraction	7/2053	64/18722	0.56207271985986	0.754628847428767	PTAFR/DOCK4/SOD1/ATP2B1/SPHK1/RHOA/RGS2	7
GO:0030104	water homeostasis	7/2053	64/18722	0.56207271985986	0.754628847428767	STMN1/AQP9/MET/CLDN4/LSR/AKR1B1/ATP6V1B1	7
GO:0030858	positive regulation of epithelial cell differentiation	7/2053	64/18722	0.56207271985986	0.754628847428767	CD24/NOTCH1/BTG1/AHI1/VDR/BAD/FOXC1	7
GO:0045995	regulation of embryonic development	7/2053	64/18722	0.56207271985986	0.754628847428767	PHLDA2/DAG1/CDK1/LAMA5/AMOT/INSR/CFL1	7
GO:0006869	lipid transport	43/2053	398/18722	0.565821141479308	0.759491465072897	TSPO/MSR1/NPC2/PSAP/SPP1/RETN/AQP9/IL1B/CD36/SLC2A1/SLC27A2/APOBR/APOL6/NFKBIA/SYK/TREM2/DBI/KCNQ1/P2RX7/PLIN2/APOC1/TRIAP1/FABP5/SYT7/APOL3/ACSL4/ITGAV/PLSCR1/TMEM30B/KCNN4/STARD10/NME4/FIS1/PTGES/C1QTNF1/LIMA1/SLC25A17/SIGMAR1/PITPNB/HDLBP/LDLRAP1/PPARG/SLC10A3	43
GO:0010092	specification of animal organ identity	4/2053	36/18722	0.567350435368848	0.760302035734306	MEF2C/LRP2/ISL1/GLI3	4
GO:0014741	negative regulation of muscle hypertrophy	4/2053	36/18722	0.567350435368848	0.760302035734306	TNFRSF1B/NOTCH1/RGS2/LMNA	4
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	4/2053	36/18722	0.567350435368848	0.760302035734306	HLA-DRB1/MPC2/PHPT1/BAD	4
GO:0036314	response to sterol	4/2053	36/18722	0.567350435368848	0.760302035734306	CCL3/TGFB1/DAG1/PMVK	4
GO:0038179	neurotrophin signaling pathway	4/2053	36/18722	0.567350435368848	0.760302035734306	CORO1A/DDIT4/RAP1A/BCAR1	4
GO:0045746	negative regulation of Notch signaling pathway	4/2053	36/18722	0.567350435368848	0.760302035734306	NFKBIA/BMP7/BCL6/LFNG	4
GO:0046466	membrane lipid catabolic process	4/2053	36/18722	0.567350435368848	0.760302035734306	PPT1/SPHK1/FUCA1/HEXB	4
GO:0006360	transcription by RNA polymerase I	6/2053	55/18722	0.569174095030966	0.760302035734306	FLNA/POLR2L/TCOF1/NCL/POLR2K/PWP1	6
GO:0044091	membrane biogenesis	6/2053	55/18722	0.569174095030966	0.760302035734306	EMP2/S100A10/ANK3/SPTBN1/UBXN2A/PICALM	6
GO:0062014	negative regulation of small molecule metabolic process	11/2053	102/18722	0.570517737536969	0.760302035734306	PLEK/FBP1/PARP1/PGP/SOD1/CDA/BRCA1/ACADVL/DDIT4/APOC1/STAT3	11
GO:0001829	trophectodermal cell differentiation	2/2053	17/18722	0.570606677818596	0.760302035734306	JUNB/YAP1	2
GO:0006901	vesicle coating	2/2053	17/18722	0.570606677818596	0.760302035734306	TMED9/TFG	2
GO:0007351	tripartite regional subdivision	2/2053	17/18722	0.570606677818596	0.760302035734306	BASP1/TBX3	2
GO:0008595	anterior/posterior axis specification, embryo	2/2053	17/18722	0.570606677818596	0.760302035734306	BASP1/TBX3	2
GO:0014856	skeletal muscle cell proliferation	2/2053	17/18722	0.570606677818596	0.760302035734306	JAK2/STAT3	2
GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway	2/2053	17/18722	0.570606677818596	0.760302035734306	CHMP4C/VPS25	2
GO:0035269	protein O-linked mannosylation	2/2053	17/18722	0.570606677818596	0.760302035734306	TMTC3/DPM2	2
GO:0036065	fucosylation	2/2053	17/18722	0.570606677818596	0.760302035734306	FUOM/FUT8	2
GO:0036166	phenotypic switching	2/2053	17/18722	0.570606677818596	0.760302035734306	SOD2/DNMT1	2
GO:0043649	dicarboxylic acid catabolic process	2/2053	17/18722	0.570606677818596	0.760302035734306	GLUL/QPRT	2
GO:0045815	positive regulation of gene expression, epigenetic	2/2053	17/18722	0.570606677818596	0.760302035734306	CDCA4/CHEK1	2
GO:0048339	paraxial mesoderm development	2/2053	17/18722	0.570606677818596	0.760302035734306	YAP1/FOXC1	2
GO:0055003	cardiac myofibril assembly	2/2053	17/18722	0.570606677818596	0.760302035734306	MEF2A/OBSL1	2
GO:0060644	mammary gland epithelial cell differentiation	2/2053	17/18722	0.570606677818596	0.760302035734306	CEBPB/ID2	2
GO:0070593	dendrite self-avoidance	2/2053	17/18722	0.570606677818596	0.760302035734306	BSG/PALLD	2
GO:0070875	positive regulation of glycogen metabolic process	2/2053	17/18722	0.570606677818596	0.760302035734306	HMGB1/INSR	2
GO:0090083	regulation of inclusion body assembly	2/2053	17/18722	0.570606677818596	0.760302035734306	SORL1/HSPA1A	2
GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	2/2053	17/18722	0.570606677818596	0.760302035734306	AKAP9/HOMER1	2
GO:1901569	fatty acid derivative catabolic process	2/2053	17/18722	0.570606677818596	0.760302035734306	HPGD/NUDT8	2
GO:1902358	sulfate transmembrane transport	2/2053	17/18722	0.570606677818596	0.760302035734306	SLC26A2/SLC13A4	2
GO:1903358	regulation of Golgi organization	2/2053	17/18722	0.570606677818596	0.760302035734306	PDE4DIP/AKAP9	2
GO:1903540	establishment of protein localization to postsynaptic membrane	2/2053	17/18722	0.570606677818596	0.760302035734306	NSG1/CLSTN1	2
GO:1903830	magnesium ion transmembrane transport	2/2053	17/18722	0.570606677818596	0.760302035734306	TUSC3/MRS2	2
GO:0032368	regulation of lipid transport	16/2053	149/18722	0.574613390540187	0.765300853105687	TSPO/SPP1/RETN/IL1B/NFKBIA/SYK/TREM2/DBI/APOC1/TRIAP1/ITGAV/FIS1/PTGES/C1QTNF1/LDLRAP1/PPARG	16
GO:0045834	positive regulation of lipid metabolic process	16/2053	149/18722	0.574613390540187	0.765300853105687	CD74/TGFB1/LYN/FGR/TNF/IL1B/PTK2B/FLT1/CHP1/APOC1/MID1IP1/STOML2/VAV3/PTK2/LDLRAP1/PPARG	16
GO:0019217	regulation of fatty acid metabolic process	10/2053	93/18722	0.575552825553722	0.766381924838511	CD74/IL1B/PDK4/BRCA1/ACADVL/APOC1/FABP5/MID1IP1/PRKAG2/PPARG	10
GO:0006383	transcription by RNA polymerase III	5/2053	46/18722	0.578056508350767	0.769033048803682	POLR2L/PRDX5/POLR3K/POLR2K/BDP1	5
GO:0031018	endocrine pancreas development	5/2053	46/18722	0.578056508350767	0.769033048803682	IL6R/RHEB/SOX4/CDK6/BAD	5
GO:0031057	negative regulation of histone modification	5/2053	46/18722	0.578056508350767	0.769033048803682	SPI1/DNMT1/BRCA1/SET/ZNF451	5
GO:0061462	protein localization to lysosome	5/2053	46/18722	0.578056508350767	0.769033048803682	LAPTM5/SORL1/HSPA8/LAMTOR4/MFSD1	5
GO:0015909	long-chain fatty acid transport	7/2053	65/18722	0.579064341399938	0.769520719468356	CD36/SLC2A1/SLC27A2/SYK/PLIN2/FABP5/PPARG	7
GO:0035418	protein localization to synapse	7/2053	65/18722	0.579064341399938	0.769520719468356	NSG1/DAG1/ZDHHC12/HRAS/RAP1A/DLG1/CLSTN1	7
GO:0046503	glycerolipid catabolic process	7/2053	65/18722	0.579064341399938	0.769520719468356	SORL1/GPCPD1/PLA2G7/APOC1/PRDX6/ABHD2/MGLL	7
GO:0048645	animal organ formation	7/2053	65/18722	0.579064341399938	0.769520719468356	MEF2C/LRP2/BMP7/NOTCH1/ISL1/FOLR1/GLI3	7
GO:0070613	regulation of protein processing	7/2053	65/18722	0.579064341399938	0.769520719468356	LRRK2/RUNX1/CTSZ/CARD16/ADAM8/BCL2L12/BAG2	7
GO:0010528	regulation of transposition	3/2053	27/18722	0.580811257193248	0.770136473626406	APOBEC3A/APOBEC3G/APOBEC3C	3
GO:0010529	negative regulation of transposition	3/2053	27/18722	0.580811257193248	0.770136473626406	APOBEC3A/APOBEC3G/APOBEC3C	3
GO:0010561	negative regulation of glycoprotein biosynthetic process	3/2053	27/18722	0.580811257193248	0.770136473626406	HBEGF/ITM2C/AGO2	3
GO:0032786	positive regulation of DNA-templated transcription, elongation	3/2053	27/18722	0.580811257193248	0.770136473626406	SUPT16H/BRD4/HMGN1	3
GO:0035116	embryonic hindlimb morphogenesis	3/2053	27/18722	0.580811257193248	0.770136473626406	NOTCH1/TBX3/GPC3	3
GO:0045606	positive regulation of epidermal cell differentiation	3/2053	27/18722	0.580811257193248	0.770136473626406	NOTCH1/VDR/FOXC1	3
GO:0060512	prostate gland morphogenesis	3/2053	27/18722	0.580811257193248	0.770136473626406	CRIP1/BMP7/NOTCH1	3
GO:0070861	regulation of protein exit from endoplasmic reticulum	3/2053	27/18722	0.580811257193248	0.770136473626406	SORL1/TMEM30B/SVIP	3
GO:1900746	regulation of vascular endothelial growth factor signaling pathway	3/2053	27/18722	0.580811257193248	0.770136473626406	SEMA6A/MYO1C/CD63	3
GO:1903319	positive regulation of protein maturation	3/2053	27/18722	0.580811257193248	0.770136473626406	ADAM8/SOX4/BAG2	3
GO:0006405	RNA export from nucleus	9/2053	84/18722	0.581286091501619	0.770595790766619	RAN/HHEX/NPM1/HNRNPA1/NUP214/NXT1/TPR/HNRNPA2B1/PABPN1	9
GO:0018022	peptidyl-lysine methylation	14/2053	131/18722	0.58241849467956	0.771926434300279	DNMT1/RTF1/BRCA1/EZH2/SUZ12/SMYD2/GATA3/BRD4/KMT5A/KMT2E/DPY30/RIF1/LMNA/PWP1	14
GO:0035725	sodium ion transmembrane transport	19/2053	178/18722	0.585565446840332	0.775925945459804	FXYD5/SLC8A1/FXYD3/GLRX/KCNQ1/CAMK2D/SLC6A6/CHP1/TRPM2/SLC6A4/ANK3/SLC20A1/SLC9A1/COMMD1/DLG1/DMD/PTPN3/ACTN4/SLC3A2	19
GO:0019730	antimicrobial humoral response	13/2053	122/18722	0.586873604090415	0.777487662738462	HLA-A/LYZ/SLC11A1/HLA-E/S100A12/RNASE6/CXCL10/S100A9/HMGN2/CXCL8/RPS19/DEFB1/GAPDH	13
GO:0022029	telencephalon cell migration	6/2053	56/18722	0.587377184599289	0.777811323680365	CXCR4/LRRK2/ADGRG1/LAMB1/RHOA/GLI3	6
GO:0055078	sodium ion homeostasis	6/2053	56/18722	0.587377184599289	0.777811323680365	SLC8A1/COMT/GNAI2/SLC9A1/ATP6V1B1/SLC1A3	6
GO:2001259	positive regulation of cation channel activity	8/2053	75/18722	0.587915857449263	0.778352856287639	CTSS/TMSB4X/CCR2/IFNGR2/TREM2/KCNE3/CALM2/ANK3	8
GO:0001738	morphogenesis of a polarized epithelium	10/2053	94/18722	0.589591775951518	0.779365803440787	MSN/ACTB/LAMA5/FAT1/RHOA/AHI1/DLG5/ZNRF3/DAAM1/GPC3	10
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	4/2053	37/18722	0.589720124603529	0.779365803440787	PABPC1/UPF3A/MAGOHB/MAGOH	4
GO:0006623	protein targeting to vacuole	4/2053	37/18722	0.589720124603529	0.779365803440787	LAPTM5/SORL1/HSPA8/VPS13C	4
GO:0006904	vesicle docking involved in exocytosis	4/2053	37/18722	0.589720124603529	0.779365803440787	PLEK/STXBP2/RALB/RAB3D	4
GO:0030513	positive regulation of BMP signaling pathway	4/2053	37/18722	0.589720124603529	0.779365803440787	ENG/NOTCH1/NOTCH2/GPC3	4
GO:0051567	histone H3-K9 methylation	4/2053	37/18722	0.589720124603529	0.779365803440787	DNMT1/BRCA1/RIF1/LMNA	4
GO:0071985	multivesicular body sorting pathway	4/2053	37/18722	0.589720124603529	0.779365803440787	LYST/CHMP4C/VPS25/VCP	4
GO:1900077	negative regulation of cellular response to insulin stimulus	4/2053	37/18722	0.589720124603529	0.779365803440787	IL1B/SOCS3/PRKCB/KANK1	4
GO:0060021	roof of mouth development	9/2053	85/18722	0.595977708716417	0.787462288548448	TFAP2A/FRAS1/ARID5B/DLG1/GLI3/TGFBR3/TBX3/PLEKHA1/ITGB8	9
GO:0055067	monovalent inorganic cation homeostasis	16/2053	151/18722	0.596817966496407	0.78827026934599	SLC11A1/SLC8A1/LRRK2/GRN/HVCN1/PDK4/COMT/PPT1/GNAI2/CHP1/DMXL2/SLC9A1/ATP6V1B1/TCIRG1/ATP6V0E1/SLC1A3	16
GO:0008202	steroid metabolic process	34/2053	319/18722	0.59724860321915	0.78827026934599	TSPO/NPC2/SPP1/LRP2/TNF/APP/SLC27A2/APOBR/SOD1/FDPS/HSD17B1/DHCR24/COMT/ACADVL/HINT2/SULT1A1/AKR1B1/APOC1/SF1/SQLE/FDFT1/PBX1/LRP5/LIPA/HSD17B11/PMVK/EBP/CYB5R1/LIMA1/STS/HDLBP/PLEKHA1/PRKAG2/LDLRAP1	34
GO:0006998	nuclear envelope organization	5/2053	47/18722	0.597771620920709	0.78827026934599	VRK1/PRKCB/TMEM170A/UBXN2A/LMNA	5
GO:0032008	positive regulation of TOR signaling	5/2053	47/18722	0.597771620920709	0.78827026934599	NCKAP1L/TREM2/LAMTOR4/RHEB/SLC38A9	5
GO:0043114	regulation of vascular permeability	5/2053	47/18722	0.597771620920709	0.78827026934599	TGFB1/VEGFA/TJP1/FERMT2/YES1	5
GO:0051489	regulation of filopodium assembly	5/2053	47/18722	0.597771620920709	0.78827026934599	TRPM2/NRP1/FNBP1L/RHOQ/DOCK11	5
GO:0061001	regulation of dendritic spine morphogenesis	5/2053	47/18722	0.597771620920709	0.78827026934599	ABI3/LRRK2/ACTR2/EFNA1/CFL1	5
GO:0090279	regulation of calcium ion import	5/2053	47/18722	0.597771620920709	0.78827026934599	CCL3/LGALS3/TRPV2/VDAC1/HOMER1	5
GO:0097300	programmed necrotic cell death	5/2053	47/18722	0.597771620920709	0.78827026934599	CASP1/TNF/BIRC3/SLC25A4/ARHGEF2	5
GO:0000712	resolution of meiotic recombination intermediates	2/2053	18/18722	0.60249637781074	0.78964138638367	TOP2A/TOP2B	2
GO:0002076	osteoblast development	2/2053	18/18722	0.60249637781074	0.78964138638367	CLEC5A/LRP5	2
GO:0007549	dosage compensation	2/2053	18/18722	0.60249637781074	0.78964138638367	XIST/BRCA1	2
GO:0008272	sulfate transport	2/2053	18/18722	0.60249637781074	0.78964138638367	SLC26A2/SLC13A4	2
GO:0009068	aspartate family amino acid catabolic process	2/2053	18/18722	0.60249637781074	0.78964138638367	SDS/SDSL	2
GO:0009208	pyrimidine ribonucleoside triphosphate metabolic process	2/2053	18/18722	0.60249637781074	0.78964138638367	NME4/NME1	2
GO:0010663	positive regulation of striated muscle cell apoptotic process	2/2053	18/18722	0.60249637781074	0.78964138638367	CAMK2D/BNIP3	2
GO:0010666	positive regulation of cardiac muscle cell apoptotic process	2/2053	18/18722	0.60249637781074	0.78964138638367	CAMK2D/BNIP3	2
GO:0015693	magnesium ion transport	2/2053	18/18722	0.60249637781074	0.78964138638367	TUSC3/MRS2	2
GO:0015732	prostaglandin transport	2/2053	18/18722	0.60249637781074	0.78964138638367	IL1B/PTGES	2
GO:0030299	intestinal cholesterol absorption	2/2053	18/18722	0.60249637781074	0.78964138638367	CD36/LIMA1	2
GO:0031000	response to caffeine	2/2053	18/18722	0.60249637781074	0.78964138638367	SLC8A1/HDAC2	2
GO:0032305	positive regulation of icosanoid secretion	2/2053	18/18722	0.60249637781074	0.78964138638367	IL1B/PTGES	2
GO:0035930	corticosteroid hormone secretion	2/2053	18/18722	0.60249637781074	0.78964138638367	KCNQ1/C1QTNF1	2
GO:0036499	PERK-mediated unfolded protein response	2/2053	18/18722	0.60249637781074	0.78964138638367	HSPA5/PPP1R15A	2
GO:0042693	muscle cell fate commitment	2/2053	18/18722	0.60249637781074	0.78964138638367	MEF2C/TBX3	2
GO:0043116	negative regulation of vascular permeability	2/2053	18/18722	0.60249637781074	0.78964138638367	VEGFA/FERMT2	2
GO:0060192	negative regulation of lipase activity	2/2053	18/18722	0.60249637781074	0.78964138638367	APOC1/RGS2	2
GO:0060716	labyrinthine layer blood vessel development	2/2053	18/18722	0.60249637781074	0.78964138638367	JUNB/VASH1	2
GO:0072079	nephron tubule formation	2/2053	18/18722	0.60249637781074	0.78964138638367	GATA3/IRX2	2
GO:0080182	histone H3-K4 trimethylation	2/2053	18/18722	0.60249637781074	0.78964138638367	RTF1/KMT2E	2
GO:0090493	catecholamine uptake	2/2053	18/18722	0.60249637781074	0.78964138638367	ACTB/PARK7	2
GO:0097094	craniofacial suture morphogenesis	2/2053	18/18722	0.60249637781074	0.78964138638367	MSX2/GLI3	2
GO:0097107	postsynaptic density assembly	2/2053	18/18722	0.60249637781074	0.78964138638367	ABI3/ZDHHC12	2
GO:0098877	neurotransmitter receptor transport to plasma membrane	2/2053	18/18722	0.60249637781074	0.78964138638367	NSG1/CLSTN1	2
GO:0099558	maintenance of synapse structure	2/2053	18/18722	0.60249637781074	0.78964138638367	CHCHD10/DLG1	2
GO:1900242	regulation of synaptic vesicle endocytosis	2/2053	18/18722	0.60249637781074	0.78964138638367	LRRK2/AP2M1	2
GO:1902001	fatty acid transmembrane transport	2/2053	18/18722	0.60249637781074	0.78964138638367	CD36/SLC2A1	2
GO:0030516	regulation of axon extension	10/2053	95/18722	0.603414473775577	0.790499310623026	FN1/VEGFA/SEMA4A/ARHGAP4/TRPV2/SEMA6A/NRP1/GOLGA4/TWF2/SEMA6D	10
GO:0045666	positive regulation of neuron differentiation	10/2053	95/18722	0.603414473775577	0.790499310623026	MEF2C/RARA/BMP7/TIMP2/BCL6/RHOA/ECT2/ARHGEF2/PRPF19/EIF4G1	10
GO:0000209	protein polyubiquitination	25/2053	236/18722	0.604244253712656	0.791413560854821	TRIM22/UBE2L6/TNFAIP3/UBE2T/PPIA/ANAPC11/IFI27/BRCA1/DTL/UBE2C/KLHL42/BARD1/UBE2S/UBE2D1/TRIM38/DTX3L/RNF8/RUSC1/SKP2/PRPF19/AKTIP/GABARAP/HUWE1/UBE2N/UBE4B	25
GO:0006695	cholesterol biosynthetic process	6/2053	57/18722	0.605172946370206	0.791558064747546	SOD1/FDPS/DHCR24/FDFT1/PMVK/EBP	6
GO:0050891	multicellular organismal water homeostasis	6/2053	57/18722	0.605172946370206	0.791558064747546	STMN1/MET/CLDN4/LSR/AKR1B1/ATP6V1B1	6
GO:0060042	retina morphogenesis in camera-type eye	6/2053	57/18722	0.605172946370206	0.791558064747546	TFAP2A/AHI1/LRP5/OBSL1/FJX1/PTN	6
GO:1902017	regulation of cilium assembly	6/2053	57/18722	0.605172946370206	0.791558064747546	CCDC88A/YAP1/VDAC3/ATMIN/CCP110/ODF2L	6
GO:1902653	secondary alcohol biosynthetic process	6/2053	57/18722	0.605172946370206	0.791558064747546	SOD1/FDPS/DHCR24/FDFT1/PMVK/EBP	6
GO:0010565	regulation of cellular ketone metabolic process	14/2053	133/18722	0.605919361181225	0.791558064747546	CD74/SLC7A7/IL1B/PDK4/COMT/BRCA1/ACADVL/APOC1/FABP5/MID1IP1/NCOR2/PARK7/PRKAG2/PPARG	14
GO:0010460	positive regulation of heart rate	3/2053	28/18722	0.606201551252495	0.791558064747546	KCNQ1/ADRB1/GCH1	3
GO:0032438	melanosome organization	3/2053	28/18722	0.606201551252495	0.791558064747546	ZEB2/RAB32/LYST	3
GO:0032958	inositol phosphate biosynthetic process	3/2053	28/18722	0.606201551252495	0.791558064747546	PLEK/PTAFR/PTK2B	3
GO:0042983	amyloid precursor protein biosynthetic process	3/2053	28/18722	0.606201551252495	0.791558064747546	PAWR/ITM2C/AGO2	3
GO:0042984	regulation of amyloid precursor protein biosynthetic process	3/2053	28/18722	0.606201551252495	0.791558064747546	PAWR/ITM2C/AGO2	3
GO:0071280	cellular response to copper ion	3/2053	28/18722	0.606201551252495	0.791558064747546	APP/MT1X/MT2A	3
GO:1903779	regulation of cardiac conduction	3/2053	28/18722	0.606201551252495	0.791558064747546	SLC8A1/ATP2B1/GJA5	3
GO:1990776	response to angiotensin	3/2053	28/18722	0.606201551252495	0.791558064747546	CYBB/CYBA/CDC6	3
GO:0009798	axis specification	9/2053	86/18722	0.610417027776489	0.796889070204294	WLS/NOTCH1/HSPB11/NOTCH2/AHI1/BASP1/TBX3/COBL/GPC3	9
GO:0032373	positive regulation of sterol transport	4/2053	38/18722	0.611394099566148	0.797297239164723	NFKBIA/TREM2/LDLRAP1/PPARG	4
GO:0032376	positive regulation of cholesterol transport	4/2053	38/18722	0.611394099566148	0.797297239164723	NFKBIA/TREM2/LDLRAP1/PPARG	4
GO:0032717	negative regulation of interleukin-8 production	4/2053	38/18722	0.611394099566148	0.797297239164723	TMSB4X/KLF4/TLR6/CD33	4
GO:0046676	negative regulation of insulin secretion	4/2053	38/18722	0.611394099566148	0.797297239164723	UCP2/KLF7/HADH/MIDN	4
GO:2000279	negative regulation of DNA biosynthetic process	4/2053	38/18722	0.611394099566148	0.797297239164723	DUSP1/HNRNPA1/GJA1/CDKN1A	4
GO:0009755	hormone-mediated signaling pathway	20/2053	190/18722	0.611832973754936	0.797464278380904	JAK2/PARP1/RARA/BMP7/CALR/LGR5/BRCA1/PHB2/ISL1/RHOA/LGR4/NCOR2/YAP1/ABHD2/PHB/PGRMC2/PARK7/SKP2/PKN1/PPARG	20
GO:0051216	cartilage development	20/2053	190/18722	0.611832973754936	0.797464278380904	TIMP1/CD44/TGFB1/TGFBI/MEF2C/EFEMP1/TYMS/RUNX1/RARA/BMP7/TRPS1/SERPINH1/RUNX3/SULF2/SCIN/GLI3/MDK/SMAD5/ITGB8/MAPK14	20
GO:0042490	mechanoreceptor differentiation	7/2053	67/18722	0.612053833657344	0.797464278380904	SOD1/NOTCH1/KCNQ1/MCOLN3/ESRP1/TRIOBP/MYO7A	7
GO:0061371	determination of heart left/right asymmetry	7/2053	67/18722	0.612053833657344	0.797464278380904	MEF2C/ENG/NOTCH1/NOTCH2/AHI1/FOLR1/TBX3	7
GO:0070588	calcium ion transmembrane transport	33/2053	312/18722	0.614841042526927	0.800921896474503	PTPRC/CORO1A/CCL3/CYBA/LYN/SLC8A1/CXCL10/ORAI2/PTPN6/ATP2B1/CATSPER1/PTK2B/TRPV2/P2RX7/VMP1/TSPAN13/CAMK2D/KCNE3/TRPM2/CALM2/C4orf3/MCOLN3/ITGAV/VDAC1/STOML2/AFG3L2/YWHAE/SLC9A1/MCUR1/DMD/FKBP1A/PMPCB/UBASH3B	33
GO:0090596	sensory organ morphogenesis	27/2053	256/18722	0.615366557190006	0.801432459982644	MAFB/EFEMP1/FBN2/VEGFA/FBN1/SOD1/TENM3/C12orf57/BMP7/KCNQ1/MFAP5/FAT1/TFAP2A/NOTCH2/STAT3/HDAC2/AHI1/GATA3/LRP5/HMGN1/OBSL1/ATP6V1B1/GLI3/FJX1/PTN/TRIOBP/MYO7A	27
GO:0032527	protein exit from endoplasmic reticulum	5/2053	48/18722	0.616957510905354	0.803048600851445	SORL1/HSP90B1/TMEM30B/SVIP/VCP	5
GO:1902003	regulation of amyloid-beta formation	5/2053	48/18722	0.616957510905354	0.803048600851445	SORL1/TNF/EFNA1/IFNGR1/PICALM	5
GO:0044264	cellular polysaccharide metabolic process	10/2053	96/18722	0.61700900832086	0.803048600851445	HMGB1/PHLDA2/AOAH/AGL/IL6ST/UGP2/GAA/INSR/PHKB/PRKAG2	10
GO:0035904	aorta development	6/2053	58/18722	0.622540508280836	0.810072229383001	LRP2/ENG/NOTCH1/ADAMTS6/SOX4/CNTRL	6
GO:0007585	respiratory gaseous exchange by respiratory system	7/2053	68/18722	0.628015826876046	0.81462891984502	MAFB/NR4A2/ADH5/CYSLTR1/CSF2RB/FUT8/GAA	7
GO:0061912	selective autophagy	7/2053	68/18722	0.628015826876046	0.81462891984502	SLC25A5/PHB2/SLC25A4/VDAC1/VPS13C/HUWE1/WIPI2	7
GO:1901016	regulation of potassium ion transmembrane transporter activity	7/2053	68/18722	0.628015826876046	0.81462891984502	ITGB1/TREM2/KCNE3/ANK3/YWHAE/DLG1/AKAP9	7
GO:0031503	protein-containing complex localization	23/2053	220/18722	0.628537110853255	0.81462891984502	TYROBP/TNFAIP2/RAN/NSG1/DAG1/HHEX/NPM1/NUP214/HSPB11/BIRC5/HRAS/RALB/TPR/RAP1A/HNRNPA2B1/EZR/DLG1/NUMB/PABPN1/AKAP9/AP2M1/PURA/CLSTN1	23
GO:0031123	RNA 3'-end processing	12/2053	116/18722	0.62908231742718	0.81462891984502	RPS21/APP/PABPC1/SLBP/LIN28B/ZFP36L1/EXOSC8/BARD1/POLR3K/WDR33/FBL/TOE1	12
GO:0006694	steroid biosynthetic process	18/2053	173/18722	0.629935879507406	0.81462891984502	TSPO/TNF/SLC27A2/SOD1/FDPS/HSD17B1/DHCR24/HINT2/AKR1B1/SF1/SQLE/FDFT1/PBX1/HSD17B11/PMVK/EBP/CYB5R1/PRKAG2	18
GO:0003309	type B pancreatic cell differentiation	3/2053	29/18722	0.630546444967919	0.81462891984502	RHEB/CDK6/BAD	3
GO:0010390	histone monoubiquitination	3/2053	29/18722	0.630546444967919	0.81462891984502	DDB1/DTX3L/UHRF1	3
GO:0021772	olfactory bulb development	3/2053	29/18722	0.630546444967919	0.81462891984502	LRRK2/ATF5/ID2	3
GO:0030970	retrograde protein transport, ER to cytosol	3/2053	29/18722	0.630546444967919	0.81462891984502	HSP90B1/SVIP/VCP	3
GO:0032366	intracellular sterol transport	3/2053	29/18722	0.630546444967919	0.81462891984502	NPC2/SYT7/LDLRAP1	3
GO:0032367	intracellular cholesterol transport	3/2053	29/18722	0.630546444967919	0.81462891984502	NPC2/SYT7/LDLRAP1	3
GO:0043153	entrainment of circadian clock by photoperiod	3/2053	29/18722	0.630546444967919	0.81462891984502	NR2F6/BHLHE40/ID2	3
GO:0048665	neuron fate specification	3/2053	29/18722	0.630546444967919	0.81462891984502	ISL1/ESRP1/GLI3	3
GO:0048753	pigment granule organization	3/2053	29/18722	0.630546444967919	0.81462891984502	ZEB2/RAB32/LYST	3
GO:0051654	establishment of mitochondrion localization	3/2053	29/18722	0.630546444967919	0.81462891984502	UBB/ARMCX3/LRPPRC	3
GO:0051873	killing by host of symbiont cells	3/2053	29/18722	0.630546444967919	0.81462891984502	TREM1/MYD88/GAPDH	3
GO:0051883	killing of cells in other organism involved in symbiotic interaction	3/2053	29/18722	0.630546444967919	0.81462891984502	TREM1/MYD88/GAPDH	3
GO:0062098	regulation of programmed necrotic cell death	3/2053	29/18722	0.630546444967919	0.81462891984502	BIRC3/SLC25A4/ARHGEF2	3
GO:0072539	T-helper 17 cell differentiation	3/2053	29/18722	0.630546444967919	0.81462891984502	IL6R/STAT3/NFKBIZ	3
GO:1902547	regulation of cellular response to vascular endothelial growth factor stimulus	3/2053	29/18722	0.630546444967919	0.81462891984502	SEMA6A/MYO1C/CD63	3
GO:1903513	endoplasmic reticulum to cytosol transport	3/2053	29/18722	0.630546444967919	0.81462891984502	HSP90B1/SVIP/VCP	3
GO:0007618	mating	4/2053	39/18722	0.632345210972577	0.81462891984502	APP/SLC6A4/HDAC2/HEXB	4
GO:0045823	positive regulation of heart contraction	4/2053	39/18722	0.632345210972577	0.81462891984502	KCNQ1/ADRB1/RGS2/GCH1	4
GO:0045923	positive regulation of fatty acid metabolic process	4/2053	39/18722	0.632345210972577	0.81462891984502	CD74/IL1B/MID1IP1/PPARG	4
GO:0046621	negative regulation of organ growth	4/2053	39/18722	0.632345210972577	0.81462891984502	GJA1/SLC6A4/RGS2/STK4	4
GO:1901021	positive regulation of calcium ion transmembrane transporter activity	4/2053	39/18722	0.632345210972577	0.81462891984502	VMP1/KCNE3/CALM2/SLC9A1	4
GO:0006071	glycerol metabolic process	2/2053	19/18722	0.632559356259658	0.81462891984502	PGP/GK	2
GO:0006491	N-glycan processing	2/2053	19/18722	0.632559356259658	0.81462891984502	FUT8/GANAB	2
GO:0006670	sphingosine metabolic process	2/2053	19/18722	0.632559356259658	0.81462891984502	SPHK1/PLPP3	2
GO:0007530	sex determination	2/2053	19/18722	0.632559356259658	0.81462891984502	SF1/MAP3K4	2
GO:0007603	phototransduction, visible light	2/2053	19/18722	0.632559356259658	0.81462891984502	GNA11/NMT1	2
GO:0009226	nucleotide-sugar biosynthetic process	2/2053	19/18722	0.632559356259658	0.81462891984502	UXS1/GFPT1	2
GO:0010002	cardioblast differentiation	2/2053	19/18722	0.632559356259658	0.81462891984502	NOTCH1/ISL1	2
GO:0010738	regulation of protein kinase A signaling	2/2053	19/18722	0.632559356259658	0.81462891984502	LRRK2/PDE4A	2
GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling	2/2053	19/18722	0.632559356259658	0.81462891984502	KLF4/TREM2	2
GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	2/2053	19/18722	0.632559356259658	0.81462891984502	TECR/ACSL4	2
GO:0036498	IRE1-mediated unfolded protein response	2/2053	19/18722	0.632559356259658	0.81462891984502	HSPA5/DNAJB9	2
GO:0043031	negative regulation of macrophage activation	2/2053	19/18722	0.632559356259658	0.81462891984502	PTPRC/GRN	2
GO:0044320	cellular response to leptin stimulus	2/2053	19/18722	0.632559356259658	0.81462891984502	CCNA2/STAT3	2
GO:0045603	positive regulation of endothelial cell differentiation	2/2053	19/18722	0.632559356259658	0.81462891984502	NOTCH1/BTG1	2
GO:0046033	AMP metabolic process	2/2053	19/18722	0.632559356259658	0.81462891984502	ADK/AMPD3	2
GO:0046782	regulation of viral transcription	2/2053	19/18722	0.632559356259658	0.81462891984502	ZFP36/IFITM3	2
GO:0051546	keratinocyte migration	2/2053	19/18722	0.632559356259658	0.81462891984502	HBEGF/FERMT1	2
GO:0060039	pericardium development	2/2053	19/18722	0.632559356259658	0.81462891984502	BMP7/NOTCH1	2
GO:0070233	negative regulation of T cell apoptotic process	2/2053	19/18722	0.632559356259658	0.81462891984502	TSC22D3/EFNA1	2
GO:1901881	positive regulation of protein depolymerization	2/2053	19/18722	0.632559356259658	0.81462891984502	PLEK/DSTN	2
GO:2000831	regulation of steroid hormone secretion	2/2053	19/18722	0.632559356259658	0.81462891984502	RETN/C1QTNF1	2
GO:0034637	cellular carbohydrate biosynthetic process	8/2053	78/18722	0.633336619113088	0.815279921621653	ISYNA1/FBP1/PGP/AGL/AKR1B1/IMPA2/UGP2/INSR	8
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	8/2053	78/18722	0.633336619113088	0.815279921621653	KLF4/VEGFA/HMOX1/NOTCH1/NRP1/RHOA/CIB1/PLK2	8
GO:0000959	mitochondrial RNA metabolic process	5/2053	49/18722	0.635592147700394	0.816956108288556	TFAM/MRPL12/SLIRP/CHCHD10/LRPPRC	5
GO:0009395	phospholipid catabolic process	5/2053	49/18722	0.635592147700394	0.816956108288556	GPCPD1/PLA2G7/APOC1/PRDX6/IDH1	5
GO:0021515	cell differentiation in spinal cord	5/2053	49/18722	0.635592147700394	0.816956108288556	NOTCH1/LMO4/ISL1/SOX4/GLI3	5
GO:0021695	cerebellar cortex development	5/2053	49/18722	0.635592147700394	0.816956108288556	HSPA5/EZH2/UQCRQ/RERE/MDK	5
GO:0051932	synaptic transmission, GABAergic	5/2053	49/18722	0.635592147700394	0.816956108288556	ZDHHC12/EZH2/TPBG/GABRE/RAC3	5
GO:0005976	polysaccharide metabolic process	11/2053	107/18722	0.635864170951259	0.816956108288556	TGFB1/HMGB1/PHLDA2/AOAH/AGL/IL6ST/UGP2/GAA/INSR/PHKB/PRKAG2	11
GO:0042303	molting cycle	11/2053	107/18722	0.635864170951259	0.816956108288556	EGFR/TNF/LAMA5/SNRPE/NOTCH1/HPSE/LGR5/FERMT1/HDAC2/LGR4/PDGFA	11
GO:0042633	hair cycle	11/2053	107/18722	0.635864170951259	0.816956108288556	EGFR/TNF/LAMA5/SNRPE/NOTCH1/HPSE/LGR5/FERMT1/HDAC2/LGR4/PDGFA	11
GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	11/2053	107/18722	0.635864170951259	0.816956108288556	LAPTM5/LRRK2/PLK3/PTK2B/TRIB1/MAGEF1/HSPA1A/VCP/PLK2/GABARAP/PTK2	11
GO:0021885	forebrain cell migration	6/2053	59/18722	0.639462008882942	0.8208754927894	CXCR4/LRRK2/ADGRG1/LAMB1/RHOA/GLI3	6
GO:0051568	histone H3-K4 methylation	6/2053	59/18722	0.639462008882942	0.8208754927894	DNMT1/RTF1/BRCA1/GATA3/KMT2E/DPY30	6
GO:0071806	protein transmembrane transport	6/2053	59/18722	0.639462008882942	0.8208754927894	HSPD1/HSPA5/MCL1/TOMM40/SEC63/DNAJC19	6
GO:2000351	regulation of endothelial cell apoptotic process	6/2053	59/18722	0.639462008882942	0.8208754927894	TNF/TNFAIP3/ITGA4/ICAM1/RGCC/GATA3	6
GO:0006650	glycerophospholipid metabolic process	32/2053	306/18722	0.640159040768038	0.82159449082529	PLEK/CSF1R/LPCAT2/PGP/SOCS3/GPCPD1/PLCB2/PLA2G7/DBI/AGPAT2/PHB2/CHPT1/GPAA1/APOC1/PGAP2/FABP5/SH3YL1/PRDX6/PLSCR1/SERINC2/IMPA2/STOML2/DNAJC19/DGKD/INPP5D/CDS1/SLC44A1/PISD/CDIPT/SLC44A2/PDGFA/DPM2	32
GO:0014902	myotube differentiation	12/2053	117/18722	0.641122027060337	0.822654440197182	CD53/CD9/MEF2C/GPX1/PLEKHO1/CXCL10/ERVW-1/NOTCH1/KLF5/BHLHE41/HOMER1/MAPK14	12
GO:0043414	macromolecule methylation	33/2053	316/18722	0.644689173878599	0.82705474519384	SPI1/FOS/HELLS/PARP1/DNMT1/SNRPB/RTF1/BRCA1/BTG2/EZH2/BTG1/TRMT1/SUZ12/SNRPD3/SMYD2/GATA3/BRD4/RAB3D/KDM1B/ICMT/KMT5A/MIS18A/KMT2E/DPY30/RIF1/LCMT1/TRIM28/NTMT1/LMNA/MBD2/FBL/PWP1/MBD3	33
GO:2001257	regulation of cation channel activity	19/2053	184/18722	0.644878207513217	0.82712040296693	CTSS/TMSB4X/MEF2C/APP/CCR2/IFNGR2/ITGB1/TREM2/KCNQ1/PTK2B/CAMK2D/KCNE3/CALM2/ANK3/DLG1/DMD/FKBP1A/CAPN1/HOMER1	19
GO:0050772	positive regulation of axonogenesis	8/2053	79/18722	0.647843802249768	0.830627127722923	FN1/SKIL/VEGFA/PLXNC1/TRPV2/NRP1/GOLGA4/TWF2	8
GO:0034660	ncRNA metabolic process	51/2053	485/18722	0.64788915962388	0.830627127722923	RPS21/ISG20/PA2G4/RPS17/RPS7/RPS27/PRKDC/RPS16/RPS14/RPL5/LIN28B/RPL7A/POP7/EXOSC8/RPS19/TRMT1/NOP56/HRAS/RPL35/IARS2/NHP2/RPL10A/STAT3/POLR3K/NOP58/RPL14/TSEN34/RBFA/RPS6/RPS8/KHSRP/SNU13/MRPL1/RPL7/SND1/HNRNPA2B1/IMP3/WDR18/SBDS/DDX1/KRR1/BRIX1/AGO2/WBP11/RPS25/DDX18/FBL/PWP1/TOE1/MRTO4/BMS1	51
GO:0032259	methylation	38/2053	364/18722	0.652184135102944	0.834850489093814	SPI1/FOS/TYMS/HELLS/PARP1/DNMT1/SNRPB/COMT/RTF1/BRCA1/BTG2/EZH2/BTG1/TRMT1/MTAP/SUZ12/SNRPD3/SMYD2/GATA3/BRD4/RAB3D/KDM1B/ICMT/COMTD1/KMT5A/MIS18A/KMT2E/DPY30/RIF1/LCMT1/TRIM28/NTMT1/LMNA/MBD2/FBL/PWP1/MTR/MBD3	38
GO:0055081	anion homeostasis	4/2053	40/18722	0.652553021249072	0.834850489093814	TBXAS1/KCNQ1/KCNE3/ATP6V1B1	4
GO:0060412	ventricular septum morphogenesis	4/2053	40/18722	0.652553021249072	0.834850489093814	NOTCH1/SOX4/TGFBR3/TBX3	4
GO:0070266	necroptotic process	4/2053	40/18722	0.652553021249072	0.834850489093814	TNF/BIRC3/SLC25A4/ARHGEF2	4
GO:1901661	quinone metabolic process	4/2053	40/18722	0.652553021249072	0.834850489093814	AKR7A2/AKR1B1/COQ4/VKORC1	4
GO:0018023	peptidyl-lysine trimethylation	5/2053	50/18722	0.653657733780308	0.834850489093814	RTF1/BRD4/KMT2E/LMNA/PWP1	5
GO:0043628	ncRNA 3'-end processing	5/2053	50/18722	0.653657733780308	0.834850489093814	RPS21/EXOSC8/POLR3K/FBL/TOE1	5
GO:0051646	mitochondrion localization	5/2053	50/18722	0.653657733780308	0.834850489093814	LRRK2/MEF2A/UBB/ARMCX3/LRPPRC	5
GO:1901570	fatty acid derivative biosynthetic process	5/2053	50/18722	0.653657733780308	0.834850489093814	ALOX5/TECR/PPT1/SLC25A1/ACSL4	5
GO:0006644	phospholipid metabolic process	40/2053	383/18722	0.65376176514898	0.834850489093814	PLEK/CSF1R/LPCAT2/ISYNA1/PGP/SOCS3/GPCPD1/PLCB2/FDPS/PLA2G7/DBI/AGPAT2/PHB2/CHPT1/CHP1/GPAA1/APOC1/PGAP2/FABP5/SH3YL1/FDFT1/PRDX6/PLPP3/PLSCR1/PMVK/SERINC2/IMPA2/STOML2/DNAJC19/IDH1/DGKD/INPP5D/CDS1/SLC44A1/PISD/CDIPT/HEXB/SLC44A2/PDGFA/DPM2	40
GO:0006884	cell volume homeostasis	3/2053	30/18722	0.653827074708639	0.834850489093814	NPM1/P2RX7/KCNN4	3
GO:0008209	androgen metabolic process	3/2053	30/18722	0.653827074708639	0.834850489093814	SPP1/HSD17B11/PLEKHA1	3
GO:0030204	chondroitin sulfate metabolic process	3/2053	30/18722	0.653827074708639	0.834850489093814	CHPF/CHST15/DSE	3
GO:0031365	N-terminal protein amino acid modification	3/2053	30/18722	0.653827074708639	0.834850489093814	SOX4/NMT1/NTMT1	3
GO:0045940	positive regulation of steroid metabolic process	3/2053	30/18722	0.653827074708639	0.834850489093814	TNF/APOC1/LDLRAP1	3
GO:0045948	positive regulation of translational initiation	3/2053	30/18722	0.653827074708639	0.834850489093814	TNF/EIF2AK4/PPP1R15A	3
GO:0048799	animal organ maturation	3/2053	30/18722	0.653827074708639	0.834850489093814	SNX10/RHOA/GATA3	3
GO:0060292	long-term synaptic depression	3/2053	30/18722	0.653827074708639	0.834850489093814	LILRB2/PTK2B/PLK2	3
GO:1900101	regulation of endoplasmic reticulum unfolded protein response	3/2053	30/18722	0.653827074708639	0.834850489093814	HSPA5/PPP1R15A/DNAJB9	3
GO:0060041	retina development in camera-type eye	15/2053	147/18722	0.655683721310946	0.837043048482059	SERPINF1/RRM1/PFDN5/ATP2B1/TFAP2A/NRP1/AHI1/LRP5/COL4A1/OBSL1/IMPDH2/TCIRG1/FJX1/PTN/ACTL6A	15
GO:0003407	neural retina development	7/2053	70/18722	0.658800867158516	0.8403720996753	ATP2B1/TFAP2A/AHI1/OBSL1/FJX1/PTN/ACTL6A	7
GO:0006821	chloride transport	11/2053	109/18722	0.660481475914988	0.8403720996753	TSPO/PTAFR/FXYD3/SLC26A2/CLDN4/CLIC1/TTYH3/GABRE/BEST1/PCYOX1/SLC1A3	11
GO:0034766	negative regulation of ion transmembrane transport	11/2053	109/18722	0.660481475914988	0.8403720996753	HAMP/CAMK2D/KCNE3/CALM2/C4orf3/ANK3/VDAC1/GOPC/YWHAE/RGS2/COMMD1	11
GO:0006590	thyroid hormone generation	2/2053	20/18722	0.660812594378011	0.8403720996753	CTSB/GATA3	2
GO:0006700	C21-steroid hormone biosynthetic process	2/2053	20/18722	0.660812594378011	0.8403720996753	TSPO/AKR1B1	2
GO:0017121	plasma membrane phospholipid scrambling	2/2053	20/18722	0.660812594378011	0.8403720996753	P2RX7/PLSCR1	2
GO:0030150	protein import into mitochondrial matrix	2/2053	20/18722	0.660812594378011	0.8403720996753	TOMM40/DNAJC19	2
GO:0042359	vitamin D metabolic process	2/2053	20/18722	0.660812594378011	0.8403720996753	LRP2/TNF	2
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	2/2053	20/18722	0.660812594378011	0.8403720996753	ITM2C/AGO2	2
GO:0043651	linoleic acid metabolic process	2/2053	20/18722	0.660812594378011	0.8403720996753	ALOX5/GSTP1	2
GO:0043984	histone H4-K16 acetylation	2/2053	20/18722	0.660812594378011	0.8403720996753	BRCA1/PHF20	2
GO:0071625	vocalization behavior	2/2053	20/18722	0.660812594378011	0.8403720996753	CNTNAP2/GLI3	2
GO:0097150	neuronal stem cell population maintenance	2/2053	20/18722	0.660812594378011	0.8403720996753	NOTCH1/ASPM	2
GO:0097320	plasma membrane tubulation	2/2053	20/18722	0.660812594378011	0.8403720996753	FNBP1L/PACSIN3	2
GO:1903817	negative regulation of voltage-gated potassium channel activity	2/2053	20/18722	0.660812594378011	0.8403720996753	KCNE3/ANK3	2
GO:1904292	regulation of ERAD pathway	2/2053	20/18722	0.660812594378011	0.8403720996753	USP14/SVIP	2
GO:2000479	regulation of cAMP-dependent protein kinase activity	2/2053	20/18722	0.660812594378011	0.8403720996753	PKIB/PRKAG2	2
GO:2000678	negative regulation of transcription regulatory region DNA binding	2/2053	20/18722	0.660812594378011	0.8403720996753	TMSB4X/MSX2	2
GO:0035107	appendage morphogenesis	14/2053	138/18722	0.661848926948906	0.841333381714711	FBN2/BMP7/NOTCH1/TFAP2A/FRAS1/NOTCH2/SOX4/HDAC2/PBX1/LRP5/MBNL1/GLI3/TBX3/GPC3	14
GO:0035108	limb morphogenesis	14/2053	138/18722	0.661848926948906	0.841333381714711	FBN2/BMP7/NOTCH1/TFAP2A/FRAS1/NOTCH2/SOX4/HDAC2/PBX1/LRP5/MBNL1/GLI3/TBX3/GPC3	14
GO:0042475	odontogenesis of dentin-containing tooth	9/2053	90/18722	0.665412686319568	0.845559857973326	PERP/BSG/BMP7/LAMA5/RELT/HDAC2/TCIRG1/GLI3/FOXC1	9
GO:0016050	vesicle organization	31/2053	300/18722	0.665455608225007	0.845559857973326	SRGN/CORO1A/ZEB2/RAB32/SNX10/STX11/LYST/TMED9/S100A10/SAMD9/CHP1/SPHK1/FBXO5/SYT7/SDCBP/FNBP1L/STX10/HOOK2/VAV3/CORO1C/CD2AP/CHMP4C/VPS25/PICALM/AKTIP/AP2M1/TFG/EEA1/MYO7A/SEC31A/STX6	31
GO:0065002	intracellular protein transmembrane transport	5/2053	51/18722	0.671140450460974	0.851286758863561	HSPD1/HSPA5/TOMM40/SEC63/DNAJC19	5
GO:0050994	regulation of lipid catabolic process	6/2053	61/18722	0.671909693074852	0.851286758863561	SORL1/TNF/IL1B/APOC1/CDK4/IDH1	6
GO:0060997	dendritic spine morphogenesis	6/2053	61/18722	0.671909693074852	0.851286758863561	ABI3/LRRK2/DOCK10/ACTR2/EFNA1/CFL1	6
GO:0001953	negative regulation of cell-matrix adhesion	4/2053	41/18722	0.672003251320448	0.851286758863561	BCL6/RASA1/CDKN2A/CORO1C	4
GO:0010907	positive regulation of glucose metabolic process	4/2053	41/18722	0.672003251320448	0.851286758863561	HMGB1/PMAIP1/DDB1/INSR	4
GO:1903524	positive regulation of blood circulation	4/2053	41/18722	0.672003251320448	0.851286758863561	KCNQ1/ADRB1/RGS2/GCH1	4
GO:0006939	smooth muscle contraction	11/2053	110/18722	0.67243183430408	0.851286758863561	SLC8A1/PTAFR/DOCK4/SOD1/ATP2B1/SULF2/SPHK1/RHOA/RGS2/DLG1/TBX3	11
GO:0061387	regulation of extent of cell growth	11/2053	110/18722	0.67243183430408	0.851286758863561	FN1/SPP1/VEGFA/SEMA4A/ARHGAP4/TRPV2/SEMA6A/NRP1/GOLGA4/TWF2/SEMA6D	11
GO:0008344	adult locomotory behavior	7/2053	71/18722	0.673600755487088	0.851286758863561	NR4A2/APP/ARRB2/CSTB/PPT1/EPS8/PARK7	7
GO:0018200	peptidyl-glutamic acid modification	3/2053	31/18722	0.676034984900072	0.851286758863561	PARP1/CFAP20/VKORC1	3
GO:0021988	olfactory lobe development	3/2053	31/18722	0.676034984900072	0.851286758863561	LRRK2/ATF5/ID2	3
GO:0030149	sphingolipid catabolic process	3/2053	31/18722	0.676034984900072	0.851286758863561	PPT1/SPHK1/HEXB	3
GO:0042133	neurotransmitter metabolic process	3/2053	31/18722	0.676034984900072	0.851286758863561	COMT/SLC6A4/GCHFR	3
GO:0045987	positive regulation of smooth muscle contraction	3/2053	31/18722	0.676034984900072	0.851286758863561	PTAFR/SPHK1/RHOA	3
GO:0070633	transepithelial transport	3/2053	31/18722	0.676034984900072	0.851286758863561	ACTB/BEST1/SLC1A3	3
GO:0019935	cyclic-nucleotide-mediated signaling	9/2053	91/18722	0.678422483483655	0.851286758863561	CD36/PTK2B/PDE4A/CAP1/GNAI1/NUDT4/RGS2/DEFB1/ADGRG6	9
GO:0098661	inorganic anion transmembrane transport	9/2053	91/18722	0.678422483483655	0.851286758863561	PTAFR/SLC26A2/SLC25A3/SLC13A4/SLC20A1/GABRE/BEST1/PCYOX1/SLC1A3	9
GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	13/2053	130/18722	0.679479052924085	0.851286758863561	SORL1/LRRK2/LMAN1/TMED4/TMED9/ERGIC2/ERGIC3/TMED3/GOPC/VCP/TFG/KDELR2/SEC31A	13
GO:0006956	complement activation	13/2053	130/18722	0.679479052924085	0.851286758863561	FCN1/CFD/CFP/IL1B/C3/CD46/TREM2/C1QA/CD59/C1QBP/RGCC/PHB/SERPING1	13
GO:0030534	adult behavior	13/2053	130/18722	0.679479052924085	0.851286758863561	NR4A2/APP/ARRB2/CSTB/PPT1/CNTNAP2/HDAC2/EPS8/PARK7/ATP6V1B1/CHRNB1/CHRNA5/HOMER1	13
GO:0015718	monocarboxylic acid transport	11/2053	111/18722	0.68413499260829	0.851286758863561	SLC16A3/AQP9/IL1B/CD36/SYK/MPC2/SLC16A12/SLC16A1/PTGES/MPC1/SLC10A3	11
GO:0000050	urea cycle	1/2053	10/18722	0.687071985004237	0.851286758863561	ASS1	1
GO:0000098	sulfur amino acid catabolic process	1/2053	10/18722	0.687071985004237	0.851286758863561	CDO1	1
GO:0000338	protein deneddylation	1/2053	10/18722	0.687071985004237	0.851286758863561	COPS3	1
GO:0000492	box C/D snoRNP assembly	1/2053	10/18722	0.687071985004237	0.851286758863561	SNU13	1
GO:0001672	regulation of chromatin assembly or disassembly	1/2053	10/18722	0.687071985004237	0.851286758863561	TLK1	1
GO:0002084	protein depalmitoylation	1/2053	10/18722	0.687071985004237	0.851286758863561	PPT1	1
GO:0006646	phosphatidylethanolamine biosynthetic process	1/2053	10/18722	0.687071985004237	0.851286758863561	PISD	1
GO:0007028	cytoplasm organization	1/2053	10/18722	0.687071985004237	0.851286758863561	TFCP2L1	1
GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	1/2053	10/18722	0.687071985004237	0.851286758863561	GNAS	1
GO:0009133	nucleoside diphosphate biosynthetic process	1/2053	10/18722	0.687071985004237	0.851286758863561	DTYMK	1
GO:0009750	response to fructose	1/2053	10/18722	0.687071985004237	0.851286758863561	KRT18	1
GO:0010172	embryonic body morphogenesis	1/2053	10/18722	0.687071985004237	0.851286758863561	DAG1	1
GO:0010968	regulation of microtubule nucleation	1/2053	10/18722	0.687071985004237	0.851286758863561	HSPA1A	1
GO:0015808	L-alanine transport	1/2053	10/18722	0.687071985004237	0.851286758863561	SLC3A2	1
GO:0016139	glycoside catabolic process	1/2053	10/18722	0.687071985004237	0.851286758863561	FUCA1	1
GO:0016559	peroxisome fission	1/2053	10/18722	0.687071985004237	0.851286758863561	FIS1	1
GO:0019532	oxalate transport	1/2053	10/18722	0.687071985004237	0.851286758863561	SLC26A2	1
GO:0019614	catechol-containing compound catabolic process	1/2053	10/18722	0.687071985004237	0.851286758863561	COMT	1
GO:0021548	pons development	1/2053	10/18722	0.687071985004237	0.851286758863561	UQCRQ	1
GO:0022400	regulation of rhodopsin mediated signaling pathway	1/2053	10/18722	0.687071985004237	0.851286758863561	NMT1	1
GO:0031118	rRNA pseudouridine synthesis	1/2053	10/18722	0.687071985004237	0.851286758863561	NHP2	1
GO:0031848	protection from non-homologous end joining at telomere	1/2053	10/18722	0.687071985004237	0.851286758863561	ERCC1	1
GO:0032275	luteinizing hormone secretion	1/2053	10/18722	0.687071985004237	0.851286758863561	TBX3	1
GO:0032380	regulation of intracellular sterol transport	1/2053	10/18722	0.687071985004237	0.851286758863561	LDLRAP1	1
GO:0032383	regulation of intracellular cholesterol transport	1/2053	10/18722	0.687071985004237	0.851286758863561	LDLRAP1	1
GO:0033080	immature T cell proliferation in thymus	1/2053	10/18722	0.687071985004237	0.851286758863561	IL1B	1
GO:0033089	positive regulation of T cell differentiation in thymus	1/2053	10/18722	0.687071985004237	0.851286758863561	ADAM8	1
GO:0033572	transferrin transport	1/2053	10/18722	0.687071985004237	0.851286758863561	TFRC	1
GO:0034085	establishment of sister chromatid cohesion	1/2053	10/18722	0.687071985004237	0.851286758863561	CDCA5	1
GO:0035376	sterol import	1/2053	10/18722	0.687071985004237	0.851286758863561	CD36	1
GO:0035871	protein K11-linked deubiquitination	1/2053	10/18722	0.687071985004237	0.851286758863561	TNFAIP3	1
GO:0035907	dorsal aorta development	1/2053	10/18722	0.687071985004237	0.851286758863561	ENG	1
GO:0038003	G protein-coupled opioid receptor signaling pathway	1/2053	10/18722	0.687071985004237	0.851286758863561	SIGMAR1	1
GO:0038007	netrin-activated signaling pathway	1/2053	10/18722	0.687071985004237	0.851286758863561	PTK2	1
GO:0042368	vitamin D biosynthetic process	1/2053	10/18722	0.687071985004237	0.851286758863561	TNF	1
GO:0042424	catecholamine catabolic process	1/2053	10/18722	0.687071985004237	0.851286758863561	COMT	1
GO:0042711	maternal behavior	1/2053	10/18722	0.687071985004237	0.851286758863561	MBD2	1
GO:0044848	biological phase	1/2053	10/18722	0.687071985004237	0.851286758863561	FERMT1	1
GO:0045835	negative regulation of meiotic nuclear division	1/2053	10/18722	0.687071985004237	0.851286758863561	FBXO5	1
GO:0045843	negative regulation of striated muscle tissue development	1/2053	10/18722	0.687071985004237	0.851286758863561	TGFB1	1
GO:0045898	regulation of RNA polymerase II transcription preinitiation complex assembly	1/2053	10/18722	0.687071985004237	0.851286758863561	HMGB1	1
GO:0048194	Golgi vesicle budding	1/2053	10/18722	0.687071985004237	0.851286758863561	TMED9	1
GO:0048340	paraxial mesoderm morphogenesis	1/2053	10/18722	0.687071985004237	0.851286758863561	FOXC1	1
GO:0048671	negative regulation of collateral sprouting	1/2053	10/18722	0.687071985004237	0.851286758863561	SPP1	1
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	1/2053	10/18722	0.687071985004237	0.851286758863561	CALM2	1
GO:0060068	vagina development	1/2053	10/18722	0.687071985004237	0.851286758863561	LRP2	1
GO:0060272	embryonic skeletal joint morphogenesis	1/2053	10/18722	0.687071985004237	0.851286758863561	BMP7	1
GO:0060513	prostatic bud formation	1/2053	10/18722	0.687071985004237	0.851286758863561	BMP7	1
GO:0060525	prostate glandular acinus development	1/2053	10/18722	0.687071985004237	0.851286758863561	NOTCH1	1
GO:0060736	prostate gland growth	1/2053	10/18722	0.687071985004237	0.851286758863561	PSAP	1
GO:0060923	cardiac muscle cell fate commitment	1/2053	10/18722	0.687071985004237	0.851286758863561	TBX3	1
GO:0061085	regulation of histone H3-K27 methylation	1/2053	10/18722	0.687071985004237	0.851286758863561	GATA3	1
GO:0070091	glucagon secretion	1/2053	10/18722	0.687071985004237	0.851286758863561	SYT7	1
GO:0070092	regulation of glucagon secretion	1/2053	10/18722	0.687071985004237	0.851286758863561	SYT7	1
GO:0070508	cholesterol import	1/2053	10/18722	0.687071985004237	0.851286758863561	CD36	1
GO:0070862	negative regulation of protein exit from endoplasmic reticulum	1/2053	10/18722	0.687071985004237	0.851286758863561	SVIP	1
GO:0071073	positive regulation of phospholipid biosynthetic process	1/2053	10/18722	0.687071985004237	0.851286758863561	CHP1	1
GO:0072070	loop of Henle development	1/2053	10/18722	0.687071985004237	0.851286758863561	IRX2	1
GO:0090037	positive regulation of protein kinase C signaling	1/2053	10/18722	0.687071985004237	0.851286758863561	VEGFA	1
GO:0090043	regulation of tubulin deacetylation	1/2053	10/18722	0.687071985004237	0.851286758863561	BEX4	1
GO:0090209	negative regulation of triglyceride metabolic process	1/2053	10/18722	0.687071985004237	0.851286758863561	SORL1	1
GO:0090527	actin filament reorganization	1/2053	10/18722	0.687071985004237	0.851286758863561	BCAR1	1
GO:0097250	mitochondrial respirasome assembly	1/2053	10/18722	0.687071985004237	0.851286758863561	COX7A2	1
GO:0099171	presynaptic modulation of chemical synaptic transmission	1/2053	10/18722	0.687071985004237	0.851286758863561	PRKCB	1
GO:0099639	neurotransmitter receptor transport, endosome to plasma membrane	1/2053	10/18722	0.687071985004237	0.851286758863561	NSG1	1
GO:0150172	regulation of phosphatidylcholine metabolic process	1/2053	10/18722	0.687071985004237	0.851286758863561	APOC1	1
GO:1901993	regulation of meiotic cell cycle phase transition	1/2053	10/18722	0.687071985004237	0.851286758863561	TTK	1
GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	1/2053	10/18722	0.687071985004237	0.851286758863561	PMAIP1	1
GO:1902855	regulation of non-motile cilium assembly	1/2053	10/18722	0.687071985004237	0.851286758863561	ATMIN	1
GO:1903826	arginine transmembrane transport	1/2053	10/18722	0.687071985004237	0.851286758863561	SLC38A9	1
GO:1904350	regulation of protein catabolic process in the vacuole	1/2053	10/18722	0.687071985004237	0.851286758863561	LRP2	1
GO:1905456	regulation of lymphoid progenitor cell differentiation	1/2053	10/18722	0.687071985004237	0.851286758863561	NOTCH1	1
GO:1905941	positive regulation of gonad development	1/2053	10/18722	0.687071985004237	0.851286758863561	RETN	1
GO:1990253	cellular response to leucine starvation	1/2053	10/18722	0.687071985004237	0.851286758863561	EIF2AK4	1
GO:1990700	nucleolar chromatin organization	1/2053	10/18722	0.687071985004237	0.851286758863561	SMARCA5	1
GO:2000252	negative regulation of feeding behavior	1/2053	10/18722	0.687071985004237	0.851286758863561	RETN	1
GO:2000253	positive regulation of feeding behavior	1/2053	10/18722	0.687071985004237	0.851286758863561	CFAP20	1
GO:2000659	regulation of interleukin-1-mediated signaling pathway	1/2053	10/18722	0.687071985004237	0.851286758863561	IL1RN	1
GO:0003091	renal water homeostasis	2/2053	21/18722	0.687291308611147	0.851286758863561	AKR1B1/ATP6V1B1	2
GO:0006353	DNA-templated transcription, termination	2/2053	21/18722	0.687291308611147	0.851286758863561	POLR3K/TTF2	2
GO:0009070	serine family amino acid biosynthetic process	2/2053	21/18722	0.687291308611147	0.851286758863561	DHFR/SHMT1	2
GO:0010766	negative regulation of sodium ion transport	2/2053	21/18722	0.687291308611147	0.851286758863561	CAMK2D/COMMD1	2
GO:0033962	P-body assembly	2/2053	21/18722	0.687291308611147	0.851286758863561	LSM4/LSM3	2
GO:0035020	regulation of Rac protein signal transduction	2/2053	21/18722	0.687291308611147	0.851286758863561	GABARAP/DYNLT1	2
GO:0035330	regulation of hippo signaling	2/2053	21/18722	0.687291308611147	0.851286758863561	DLG5/MAPK14	2
GO:0035813	regulation of renal sodium excretion	2/2053	21/18722	0.687291308611147	0.851286758863561	COMT/GNAI2	2
GO:0044241	lipid digestion	2/2053	21/18722	0.687291308611147	0.851286758863561	CD36/LIMA1	2
GO:0044342	type B pancreatic cell proliferation	2/2053	21/18722	0.687291308611147	0.851286758863561	NR4A1/BAD	2
GO:0046519	sphingoid metabolic process	2/2053	21/18722	0.687291308611147	0.851286758863561	SPHK1/PLPP3	2
GO:0048199	vesicle targeting, to, from or within Golgi	2/2053	21/18722	0.687291308611147	0.851286758863561	TMED9/TFG	2
GO:0048745	smooth muscle tissue development	2/2053	21/18722	0.687291308611147	0.851286758863561	ENG/DLG1	2
GO:0051152	positive regulation of smooth muscle cell differentiation	2/2053	21/18722	0.687291308611147	0.851286758863561	SOD2/ENG	2
GO:0070584	mitochondrion morphogenesis	2/2053	21/18722	0.687291308611147	0.851286758863561	SLIRP/FIS1	2
GO:0090141	positive regulation of mitochondrial fission	2/2053	21/18722	0.687291308611147	0.851286758863561	FIS1/BNIP3	2
GO:0098698	postsynaptic specialization assembly	2/2053	21/18722	0.687291308611147	0.851286758863561	ABI3/ZDHHC12	2
GO:0098719	sodium ion import across plasma membrane	2/2053	21/18722	0.687291308611147	0.851286758863561	SLC8A1/SLC9A1	2
GO:0098856	intestinal lipid absorption	2/2053	21/18722	0.687291308611147	0.851286758863561	CD36/LIMA1	2
GO:1902259	regulation of delayed rectifier potassium channel activity	2/2053	21/18722	0.687291308611147	0.851286758863561	KCNE3/ANK3	2
GO:1902644	tertiary alcohol metabolic process	2/2053	21/18722	0.687291308611147	0.851286758863561	AKR7A2/AKR1B1	2
GO:2000291	regulation of myoblast proliferation	2/2053	21/18722	0.687291308611147	0.851286758863561	MALAT1/MEIS2	2
GO:0019933	cAMP-mediated signaling	6/2053	62/18722	0.687414057782326	0.851286758863561	PDE4A/CAP1/GNAI1/RGS2/DEFB1/ADGRG6	6
GO:0031124	mRNA 3'-end processing	6/2053	62/18722	0.687414057782326	0.851286758863561	APP/PABPC1/SLBP/ZFP36L1/BARD1/WDR33	6
GO:0007129	homologous chromosome pairing at meiosis	5/2053	52/18722	0.688030194333332	0.851522517739272	CCNE1/RAD21/CCNE2/FANCD2/PSMC3IP	5
GO:0010662	regulation of striated muscle cell apoptotic process	5/2053	52/18722	0.688030194333332	0.851522517739272	JAK2/BMP7/CAMK2D/BNIP3/MDK	5
GO:0035176	social behavior	5/2053	52/18722	0.688030194333332	0.851522517739272	TREM2/KCNQ1/CX3CR1/CNTNAP2/SLC6A4	5
GO:0007032	endosome organization	8/2053	82/18722	0.689316566233924	0.85293862598547	SNX10/HOOK2/CORO1C/CHMP4C/VPS25/AKTIP/EEA1/STX6	8
GO:0014003	oligodendrocyte development	4/2053	42/18722	0.690687229818771	0.854106219891307	LYN/CD9/TLR2/GSTP1	4
GO:0021795	cerebral cortex cell migration	4/2053	42/18722	0.690687229818771	0.854106219891307	ADGRG1/LAMB1/RHOA/GLI3	4
GO:0045047	protein targeting to ER	4/2053	42/18722	0.690687229818771	0.854106219891307	HSPA5/SPCS2/SEC63/SGTB	4
GO:0006497	protein lipidation	9/2053	92/18722	0.691121365969333	0.854290934449114	GLUL/DBI/ZDHHC12/GPAA1/PGAP2/SVIP/NMT1/DPM2/WIPI2	9
GO:0070509	calcium ion import	9/2053	92/18722	0.691121365969333	0.854290934449114	CCL3/SLC8A1/LGALS3/TRPV2/TRPM2/VDAC1/AFG3L2/MCUR1/HOMER1	9
GO:0045833	negative regulation of lipid metabolic process	10/2053	102/18722	0.693245942007088	0.856564178756699	SORL1/TNF/IL1B/SOD1/ORMDL1/BRCA1/ACADVL/APOC1/SPHK1/PDGFA	10
GO:1904063	negative regulation of cation transmembrane transport	10/2053	102/18722	0.693245942007088	0.856564178756699	HAMP/CAMK2D/KCNE3/CALM2/C4orf3/ANK3/VDAC1/YWHAE/RGS2/COMMD1	10
GO:0006308	DNA catabolic process	3/2053	32/18722	0.69717076449963	0.860350593788108	ISG20/DNASE1L1/APEX1	3
GO:0006506	GPI anchor biosynthetic process	3/2053	32/18722	0.69717076449963	0.860350593788108	GPAA1/PGAP2/DPM2	3
GO:0009954	proximal/distal pattern formation	3/2053	32/18722	0.69717076449963	0.860350593788108	PBX1/GLI3/IRX2	3
GO:0021799	cerebral cortex radially oriented cell migration	3/2053	32/18722	0.69717076449963	0.860350593788108	ADGRG1/LAMB1/GLI3	3
GO:0035883	enteroendocrine cell differentiation	3/2053	32/18722	0.69717076449963	0.860350593788108	RHEB/CDK6/BAD	3
GO:0045879	negative regulation of smoothened signaling pathway	3/2053	32/18722	0.69717076449963	0.860350593788108	GLI3/VCP/GPC3	3
GO:0051865	protein autoubiquitination	7/2053	73/18722	0.701971952931207	0.866097412623327	LRRK2/UBE2T/BRCA1/RNF213/DTX3L/RNF8/UHRF1	7
GO:0001756	somitogenesis	6/2053	63/18722	0.702428431971309	0.866482440754081	PRKDC/NOTCH1/LFNG/FOXC1/COBL/XRCC2	6
GO:0060349	bone morphogenesis	9/2053	93/18722	0.703503709585292	0.866726189309958	MEF2C/RARA/SERPINH1/TFAP2A/LRP5/ACP5/MSX2/GLI3/FOXC1	9
GO:1901019	regulation of calcium ion transmembrane transporter activity	9/2053	93/18722	0.703503709585292	0.866726189309958	VMP1/CAMK2D/KCNE3/CALM2/C4orf3/YWHAE/SLC9A1/DMD/FKBP1A	9
GO:0050773	regulation of dendrite development	10/2053	103/18722	0.704994584613034	0.866726189309958	PREX1/CAMK1D/BMP7/ID1/EZH2/RHOA/ACTR2/OBSL1/PTN/COBL	10
GO:0044344	cellular response to fibroblast growth factor stimulus	11/2053	113/18722	0.706779351191294	0.866726189309958	CD44/ZFP36/ZFP36L2/ZFP36L1/NR4A1/CXCL8/SULF2/GATA3/GCLM/SHCBP1/GPC1	11
GO:0016266	O-glycan processing	4/2053	43/18722	0.708601352079018	0.866726189309958	GALNT11/C1GALT1/GXYLT1/C1GALT1C1	4
GO:0046717	acid secretion	4/2053	43/18722	0.708601352079018	0.866726189309958	SNX10/SGK1/KCNQ1/HRH2	4
GO:0090278	negative regulation of peptide hormone secretion	4/2053	43/18722	0.708601352079018	0.866726189309958	UCP2/KLF7/HADH/MIDN	4
GO:0120178	steroid hormone biosynthetic process	4/2053	43/18722	0.708601352079018	0.866726189309958	TSPO/HSD17B1/AKR1B1/HSD17B11	4
GO:0021953	central nervous system neuron differentiation	16/2053	162/18722	0.708680189043479	0.866726189309958	B2M/NR4A2/NRP2/HSP90AA1/HSP90AB1/C12orf57/LMO4/BTG2/UBB/UQCRQ/NRP1/ISL1/ZSWIM6/SOX4/GLI3/RAC3	16
GO:0046486	glycerolipid metabolic process	40/2053	392/18722	0.710705794663247	0.866726189309958	PLEK/CSF1R/SORL1/LPCAT2/GPX1/PGP/C3/SOCS3/GPCPD1/APOBR/PLCB2/PLA2G7/DBI/AGPAT2/PHB2/CHPT1/GPAA1/APOC1/PGAP2/FABP5/SH3YL1/PRDX6/ACSL4/PLSCR1/SERINC2/IMPA2/ABHD2/STOML2/DNAJC19/DGKD/INPP5D/CDS1/SLC44A1/PISD/MGLL/CDIPT/GK/SLC44A2/PDGFA/DPM2	40
GO:0006379	mRNA cleavage	2/2053	22/18722	0.712044750757598	0.866726189309958	POLR2I/AGO2	2
GO:0007398	ectoderm development	2/2053	22/18722	0.712044750757598	0.866726189309958	ITGAM/ITGA6	2
GO:0014821	phasic smooth muscle contraction	2/2053	22/18722	0.712044750757598	0.866726189309958	DLG1/TBX3	2
GO:0031061	negative regulation of histone methylation	2/2053	22/18722	0.712044750757598	0.866726189309958	DNMT1/BRCA1	2
GO:0031281	positive regulation of cyclase activity	2/2053	22/18722	0.712044750757598	0.866726189309958	TIMP2/MAPK14	2
GO:0032891	negative regulation of organic acid transport	2/2053	22/18722	0.712044750757598	0.866726189309958	FIS1/RGS2	2
GO:0035268	protein mannosylation	2/2053	22/18722	0.712044750757598	0.866726189309958	TMTC3/DPM2	2
GO:0035809	regulation of urine volume	2/2053	22/18722	0.712044750757598	0.866726189309958	GNAI2/AKR1B1	2
GO:0042430	indole-containing compound metabolic process	2/2053	22/18722	0.712044750757598	0.866726189309958	KYNU/IL4I1	2
GO:0048169	regulation of long-term neuronal synaptic plasticity	2/2053	22/18722	0.712044750757598	0.866726189309958	APP/HRAS	2
GO:0051151	negative regulation of smooth muscle cell differentiation	2/2053	22/18722	0.712044750757598	0.866726189309958	DNMT1/FOXO4	2
GO:0060563	neuroepithelial cell differentiation	2/2053	22/18722	0.712044750757598	0.866726189309958	CEBPB/SOX4	2
GO:0086012	membrane depolarization during cardiac muscle cell action potential	2/2053	22/18722	0.712044750757598	0.866726189309958	SLC8A1/ANK3	2
GO:0097164	ammonium ion metabolic process	2/2053	22/18722	0.712044750757598	0.866726189309958	ALDH7A1/SLC44A1	2
GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	2/2053	22/18722	0.712044750757598	0.866726189309958	VEGFA/HMOX1	2
GO:2000193	positive regulation of fatty acid transport	2/2053	22/18722	0.712044750757598	0.866726189309958	IL1B/PTGES	2
GO:0099177	regulation of trans-synaptic signaling	45/2053	440/18722	0.714286403846487	0.866726189309958	TYROBP/SRGN/LILRB2/MEF2C/EGFR/JAK2/LRRK2/RETN/CDH1/TNF/IL1B/APP/CCR2/ARRB2/GLUL/NSG1/MME/RARA/ITGB1/MCTP1/PTK2B/PNKD/ZDHHC12/PRKCB/CX3CR1/GNAI2/SLC6A6/HRAS/SLC6A4/STAU1/ABR/FABP5/SYT7/STAT3/RAP1A/NRGN/GNAI1/EIF2AK4/CHRNA5/PLK2/PTN/AKAP9/CLSTN1/HOMER1/SLC1A3	45
GO:0042440	pigment metabolic process	8/2053	84/18722	0.715184556855849	0.866726189309958	TSPO/ZEB2/HMOX1/PAICS/GMPS/SHMT1/PPAT/ALAD	8
GO:0030968	endoplasmic reticulum unfolded protein response	7/2053	74/18722	0.715531391698571	0.866726189309958	SERP1/HSPA5/CCND1/PPP1R15A/ATF3/VCP/DNAJB9	7
GO:1901568	fatty acid derivative metabolic process	7/2053	74/18722	0.715531391698571	0.866726189309958	ALOX5/TECR/PPT1/HPGD/NUDT8/SLC25A1/ACSL4	7
GO:1901890	positive regulation of cell junction assembly	10/2053	104/18722	0.716455530182889	0.866726189309958	VEGFA/SEMA4A/TPBG/CNTNAP2/S100A10/LIMS1/NRP1/DLG5/FERMT2/CLSTN1	10
GO:0046530	photoreceptor cell differentiation	6/2053	64/18722	0.716947988396631	0.866726189309958	VEGFA/NOTCH1/STAT3/AHI1/PTN/MYO7A	6
GO:0046888	negative regulation of hormone secretion	6/2053	64/18722	0.716947988396631	0.866726189309958	UCP2/IL1B/GJA1/KLF7/HADH/MIDN	6
GO:0050771	negative regulation of axonogenesis	6/2053	64/18722	0.716947988396631	0.866726189309958	SPP1/SEMA4A/ARHGAP4/SEMA6A/NRP1/SEMA6D	6
GO:1903018	regulation of glycoprotein metabolic process	6/2053	64/18722	0.716947988396631	0.866726189309958	CST3/HBEGF/PAWR/ITM2C/CHP1/AGO2	6
GO:0006505	GPI anchor metabolic process	3/2053	33/18722	0.717242781480498	0.866726189309958	GPAA1/PGAP2/DPM2	3
GO:0006536	glutamate metabolic process	3/2053	33/18722	0.717242781480498	0.866726189309958	GLUL/OAT/GCLM	3
GO:0009648	photoperiodism	3/2053	33/18722	0.717242781480498	0.866726189309958	NR2F6/BHLHE40/ID2	3
GO:0040020	regulation of meiotic nuclear division	3/2053	33/18722	0.717242781480498	0.866726189309958	RAD51AP1/CALR/FBXO5	3
GO:0046320	regulation of fatty acid oxidation	3/2053	33/18722	0.717242781480498	0.866726189309958	PDK4/ACADVL/PRKAG2	3
GO:0060122	inner ear receptor cell stereocilium organization	3/2053	33/18722	0.717242781480498	0.866726189309958	SOD1/TRIOBP/MYO7A	3
GO:0071539	protein localization to centrosome	3/2053	33/18722	0.717242781480498	0.866726189309958	SNX10/GOLGB1/CCDC14	3
GO:0071763	nuclear membrane organization	3/2053	33/18722	0.717242781480498	0.866726189309958	VRK1/PRKCB/UBXN2A	3
GO:2000036	regulation of stem cell population maintenance	3/2053	33/18722	0.717242781480498	0.866726189309958	BMP7/YAP1/PTN	3
GO:0061025	membrane fusion	16/2053	163/18722	0.717858383837548	0.866726189309958	CORO1A/CD9/CTSL/STX11/SPESP1/SAMD9/CHP1/SPHK1/SYT7/FOLR1/STX10/UBXN2A/VAV3/HUWE1/EEA1/STX6	16
GO:0016051	carbohydrate biosynthetic process	20/2053	202/18722	0.719472450642965	0.866726189309958	PLEK/TGFB1/ISYNA1/FBP1/SDS/PGP/PTAFR/AGL/PTK2B/SLC35B4/AKR1B1/DDB1/SLC25A1/CHST15/CHST14/FUT8/IMPA2/UGP2/ATF3/INSR	20
GO:0022412	cellular process involved in reproduction in multicellular organism	39/2053	384/18722	0.719704310892395	0.866726189309958	CD9/RETN/HMGB2/ARRB2/PRDX4/TOP2A/RARA/ITGB1/SPESP1/PTK2B/LGR5/ASPM/MSH2/UBB/RAD51C/CIB1/SLIRP/FBXO5/FOLR1/RPS6/JAM3/BRCA2/SMARCA2/KDM1B/PITHD1/ABHD2/SRPK1/TTK/ERCC1/RNF8/ING2/FOXC1/MDK/PTN/HEXB/SMAD5/DEFB1/FIGNL1/FANCA	39
GO:0032330	regulation of chondrocyte differentiation	5/2053	54/18722	0.720007312791922	0.866726189309958	EFEMP1/TRPS1/SCIN/GLI3/MDK	5
GO:0043647	inositol phosphate metabolic process	5/2053	54/18722	0.720007312791922	0.866726189309958	PLEK/PTAFR/PTK2B/IMPA2/NUDT4	5
GO:0051703	biological process involved in intraspecies interaction between organisms	5/2053	54/18722	0.720007312791922	0.866726189309958	TREM2/KCNQ1/CX3CR1/CNTNAP2/SLC6A4	5
GO:0072698	protein localization to microtubule cytoskeleton	5/2053	54/18722	0.720007312791922	0.866726189309958	SNX10/GOLGB1/KIF20B/CCDC14/TTK	5
GO:0001967	suckling behavior	1/2053	11/18722	0.721405098235655	0.866726189309958	APP	1
GO:0002327	immature B cell differentiation	1/2053	11/18722	0.721405098235655	0.866726189309958	SPI1	1
GO:0006971	hypotonic response	1/2053	11/18722	0.721405098235655	0.866726189309958	TSPO	1
GO:0009313	oligosaccharide catabolic process	1/2053	11/18722	0.721405098235655	0.866726189309958	HEXB	1
GO:0014010	Schwann cell proliferation	1/2053	11/18722	0.721405098235655	0.866726189309958	ASCL2	1
GO:0014854	response to inactivity	1/2053	11/18722	0.721405098235655	0.866726189309958	DAG1	1
GO:0015810	aspartate transmembrane transport	1/2053	11/18722	0.721405098235655	0.866726189309958	LRRC8C	1
GO:0015886	heme transport	1/2053	11/18722	0.721405098235655	0.866726189309958	PGRMC2	1
GO:0021860	pyramidal neuron development	1/2053	11/18722	0.721405098235655	0.866726189309958	UQCRQ	1
GO:0021889	olfactory bulb interneuron differentiation	1/2053	11/18722	0.721405098235655	0.866726189309958	ATF5	1
GO:0021892	cerebral cortex GABAergic interneuron differentiation	1/2053	11/18722	0.721405098235655	0.866726189309958	RAC3	1
GO:0030656	regulation of vitamin metabolic process	1/2053	11/18722	0.721405098235655	0.866726189309958	TNF	1
GO:0032276	regulation of gonadotropin secretion	1/2053	11/18722	0.721405098235655	0.866726189309958	GJA1	1
GO:0032377	regulation of intracellular lipid transport	1/2053	11/18722	0.721405098235655	0.866726189309958	LDLRAP1	1
GO:0032836	glomerular basement membrane development	1/2053	11/18722	0.721405098235655	0.866726189309958	SULF2	1
GO:0033033	negative regulation of myeloid cell apoptotic process	1/2053	11/18722	0.721405098235655	0.866726189309958	IRF7	1
GO:0033083	regulation of immature T cell proliferation	1/2053	11/18722	0.721405098235655	0.866726189309958	IL1B	1
GO:0033210	leptin-mediated signaling pathway	1/2053	11/18722	0.721405098235655	0.866726189309958	STAT3	1
GO:0033234	negative regulation of protein sumoylation	1/2053	11/18722	0.721405098235655	0.866726189309958	PARK7	1
GO:0034350	regulation of glial cell apoptotic process	1/2053	11/18722	0.721405098235655	0.866726189309958	TREM2	1
GO:0034379	very-low-density lipoprotein particle assembly	1/2053	11/18722	0.721405098235655	0.866726189309958	APOC1	1
GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'	1/2053	11/18722	0.721405098235655	0.866726189309958	EXOSC8	1
GO:0035865	cellular response to potassium ion	1/2053	11/18722	0.721405098235655	0.866726189309958	SOD1	1
GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	1/2053	11/18722	0.721405098235655	0.866726189309958	C1QBP	1
GO:0042135	neurotransmitter catabolic process	1/2053	11/18722	0.721405098235655	0.866726189309958	COMT	1
GO:0042167	heme catabolic process	1/2053	11/18722	0.721405098235655	0.866726189309958	HMOX1	1
GO:0044771	meiotic cell cycle phase transition	1/2053	11/18722	0.721405098235655	0.866726189309958	TTK	1
GO:0045161	neuronal ion channel clustering	1/2053	11/18722	0.721405098235655	0.866726189309958	CNTNAP2	1
GO:0046149	pigment catabolic process	1/2053	11/18722	0.721405098235655	0.866726189309958	HMOX1	1
GO:0046349	amino sugar biosynthetic process	1/2053	11/18722	0.721405098235655	0.866726189309958	GFPT1	1
GO:0046940	nucleoside monophosphate phosphorylation	1/2053	11/18722	0.721405098235655	0.866726189309958	DTYMK	1
GO:0048635	negative regulation of muscle organ development	1/2053	11/18722	0.721405098235655	0.866726189309958	TGFB1	1
GO:0048715	negative regulation of oligodendrocyte differentiation	1/2053	11/18722	0.721405098235655	0.866726189309958	NOTCH1	1
GO:0051610	serotonin uptake	1/2053	11/18722	0.721405098235655	0.866726189309958	SLC6A4	1
GO:0051673	membrane disruption in other organism	1/2053	11/18722	0.721405098235655	0.866726189309958	MPEG1	1
GO:0052646	alditol phosphate metabolic process	1/2053	11/18722	0.721405098235655	0.866726189309958	GK	1
GO:0060159	regulation of dopamine receptor signaling pathway	1/2053	11/18722	0.721405098235655	0.866726189309958	LRRK2	1
GO:0060174	limb bud formation	1/2053	11/18722	0.721405098235655	0.866726189309958	SOX4	1
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	1/2053	11/18722	0.721405098235655	0.866726189309958	CALM2	1
GO:0060579	ventral spinal cord interneuron fate commitment	1/2053	11/18722	0.721405098235655	0.866726189309958	GLI3	1
GO:0060581	cell fate commitment involved in pattern specification	1/2053	11/18722	0.721405098235655	0.866726189309958	GLI3	1
GO:0060746	parental behavior	1/2053	11/18722	0.721405098235655	0.866726189309958	MBD2	1
GO:0060900	embryonic camera-type eye formation	1/2053	11/18722	0.721405098235655	0.866726189309958	TFAP2A	1
GO:0070189	kynurenine metabolic process	1/2053	11/18722	0.721405098235655	0.866726189309958	KYNU	1
GO:0070314	G1 to G0 transition	1/2053	11/18722	0.721405098235655	0.866726189309958	EZH2	1
GO:0070601	centromeric sister chromatid cohesion	1/2053	11/18722	0.721405098235655	0.866726189309958	BUB1B	1
GO:0071313	cellular response to caffeine	1/2053	11/18722	0.721405098235655	0.866726189309958	SLC8A1	1
GO:0071340	skeletal muscle acetylcholine-gated channel clustering	1/2053	11/18722	0.721405098235655	0.866726189309958	PTN	1
GO:0071377	cellular response to glucagon stimulus	1/2053	11/18722	0.721405098235655	0.866726189309958	ASS1	1
GO:0071609	chemokine (C-C motif) ligand 5 production	1/2053	11/18722	0.721405098235655	0.866726189309958	SIRPA	1
GO:0071649	regulation of chemokine (C-C motif) ligand 5 production	1/2053	11/18722	0.721405098235655	0.866726189309958	SIRPA	1
GO:0072017	distal tubule development	1/2053	11/18722	0.721405098235655	0.866726189309958	NOTCH1	1
GO:0072173	metanephric tubule morphogenesis	1/2053	11/18722	0.721405098235655	0.866726189309958	LGR4	1
GO:0072497	mesenchymal stem cell differentiation	1/2053	11/18722	0.721405098235655	0.866726189309958	KRT18	1
GO:0086016	AV node cell action potential	1/2053	11/18722	0.721405098235655	0.866726189309958	GJA5	1
GO:0086027	AV node cell to bundle of His cell signaling	1/2053	11/18722	0.721405098235655	0.866726189309958	GJA5	1
GO:0086070	SA node cell to atrial cardiac muscle cell communication	1/2053	11/18722	0.721405098235655	0.866726189309958	GJA5	1
GO:0090160	Golgi to lysosome transport	1/2053	11/18722	0.721405098235655	0.866726189309958	LAPTM5	1
GO:0090205	positive regulation of cholesterol metabolic process	1/2053	11/18722	0.721405098235655	0.866726189309958	LDLRAP1	1
GO:0090394	negative regulation of excitatory postsynaptic potential	1/2053	11/18722	0.721405098235655	0.866726189309958	LRRK2	1
GO:0090481	pyrimidine nucleotide-sugar transmembrane transport	1/2053	11/18722	0.721405098235655	0.866726189309958	SLC35B4	1
GO:0090657	telomeric loop disassembly	1/2053	11/18722	0.721405098235655	0.866726189309958	BLM	1
GO:0098792	xenophagy	1/2053	11/18722	0.721405098235655	0.866726189309958	WIPI2	1
GO:0098935	dendritic transport	1/2053	11/18722	0.721405098235655	0.866726189309958	PURA	1
GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	1/2053	11/18722	0.721405098235655	0.866726189309958	NUMB	1
GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration	1/2053	11/18722	0.721405098235655	0.866726189309958	SLC8A1	1
GO:0106072	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	1/2053	11/18722	0.721405098235655	0.866726189309958	GNAI2	1
GO:1900112	regulation of histone H3-K9 trimethylation	1/2053	11/18722	0.721405098235655	0.866726189309958	LMNA	1
GO:1901862	negative regulation of muscle tissue development	1/2053	11/18722	0.721405098235655	0.866726189309958	TGFB1	1
GO:1902065	response to L-glutamate	1/2053	11/18722	0.721405098235655	0.866726189309958	PCNA	1
GO:1902093	positive regulation of flagellated sperm motility	1/2053	11/18722	0.721405098235655	0.866726189309958	DEFB1	1
GO:1902188	positive regulation of viral release from host cell	1/2053	11/18722	0.721405098235655	0.866726189309958	DDB1	1
GO:1902915	negative regulation of protein polyubiquitination	1/2053	11/18722	0.721405098235655	0.866726189309958	PPIA	1
GO:1904321	response to forskolin	1/2053	11/18722	0.721405098235655	0.866726189309958	GNAI1	1
GO:1904322	cellular response to forskolin	1/2053	11/18722	0.721405098235655	0.866726189309958	GNAI1	1
GO:1905150	regulation of voltage-gated sodium channel activity	1/2053	11/18722	0.721405098235655	0.866726189309958	KCNQ1	1
GO:2000155	positive regulation of cilium-dependent cell motility	1/2053	11/18722	0.721405098235655	0.866726189309958	DEFB1	1
GO:2000786	positive regulation of autophagosome assembly	1/2053	11/18722	0.721405098235655	0.866726189309958	RALB	1
GO:2001053	regulation of mesenchymal cell apoptotic process	1/2053	11/18722	0.721405098235655	0.866726189309958	BMP7	1
GO:0021517	ventral spinal cord development	4/2053	44/18722	0.72574655482954	0.871418717025663	LMO4/ISL1/SOX4/GLI3	4
GO:0032881	regulation of polysaccharide metabolic process	4/2053	44/18722	0.72574655482954	0.871418717025663	TGFB1/HMGB1/PHLDA2/INSR	4
GO:0051150	regulation of smooth muscle cell differentiation	4/2053	44/18722	0.72574655482954	0.871418717025663	SOD2/DNMT1/ENG/FOXO4	4
GO:0090630	activation of GTPase activity	11/2053	115/18722	0.728381254957269	0.874401941916141	GPR65/PTK2B/ARHGAP25/GMIP/ABR/RHOG/SYDE2/ECT2/CORO1C/EIF5/CCDC125	11
GO:0006094	gluconeogenesis	7/2053	75/18722	0.728668284930117	0.874401941916141	FBP1/SDS/PGP/SLC35B4/DDB1/SLC25A1/ATF3	7
GO:0045913	positive regulation of carbohydrate metabolic process	7/2053	75/18722	0.728668284930117	0.874401941916141	HMGB1/APP/PTAFR/P2RX7/PMAIP1/DDB1/INSR	7
GO:0006487	protein N-linked glycosylation	6/2053	65/18722	0.730970054192905	0.876813339695607	RPN2/DDOST/TUSC3/FUT8/GFPT1/ALG8	6
GO:0072577	endothelial cell apoptotic process	6/2053	65/18722	0.730970054192905	0.876813339695607	TNF/TNFAIP3/ITGA4/ICAM1/RGCC/GATA3	6
GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	23/2053	233/18722	0.734849910233201	0.878819736049694	FPR1/FLNA/PSAP/GPR65/GNAS/ADGRG1/PTGER4/ADGRE5/ADGRE2/CXCL10/S1PR4/RGS1/MARCO/GNA15/LGR5/GNAI2/ADRB1/LGR4/GNA11/WASF2/GNAI1/RGS2/ADGRG6	23
GO:0002067	glandular epithelial cell differentiation	5/2053	55/18722	0.735090634568017	0.878819736049694	RARA/NOTCH1/RHEB/CDK6/BAD	5
GO:0010676	positive regulation of cellular carbohydrate metabolic process	5/2053	55/18722	0.735090634568017	0.878819736049694	HMGB1/PTAFR/PMAIP1/DDB1/INSR	5
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	2/2053	23/18722	0.735132709205569	0.878819736049694	GSTP1/CARD16	2
GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	2/2053	23/18722	0.735132709205569	0.878819736049694	CLDN4/CLDN7	2
GO:0016973	poly(A)+ mRNA export from nucleus	2/2053	23/18722	0.735132709205569	0.878819736049694	HHEX/PABPN1	2
GO:0031338	regulation of vesicle fusion	2/2053	23/18722	0.735132709205569	0.878819736049694	CORO1A/SPHK1	2
GO:0033081	regulation of T cell differentiation in thymus	2/2053	23/18722	0.735132709205569	0.878819736049694	SOD1/ADAM8	2
GO:0034695	response to prostaglandin E	2/2053	23/18722	0.735132709205569	0.878819736049694	PTGER4/TGFBR3	2
GO:0035640	exploration behavior	2/2053	23/18722	0.735132709205569	0.878819736049694	LRRK2/DPP4	2
GO:0040019	positive regulation of embryonic development	2/2053	23/18722	0.735132709205569	0.878819736049694	AMOT/CFL1	2
GO:0043931	ossification involved in bone maturation	2/2053	23/18722	0.735132709205569	0.878819736049694	SNX10/RHOA	2
GO:0045943	positive regulation of transcription by RNA polymerase I	2/2053	23/18722	0.735132709205569	0.878819736049694	NCL/PWP1	2
GO:0051349	positive regulation of lyase activity	2/2053	23/18722	0.735132709205569	0.878819736049694	TIMP2/PARK7	2
GO:0051904	pigment granule transport	2/2053	23/18722	0.735132709205569	0.878819736049694	MYO5A/MYO7A	2
GO:0060487	lung epithelial cell differentiation	2/2053	23/18722	0.735132709205569	0.878819736049694	KLF2/YAP1	2
GO:0099590	neurotransmitter receptor internalization	2/2053	23/18722	0.735132709205569	0.878819736049694	NUMB/AP2M1	2
GO:0009303	rRNA transcription	3/2053	34/18722	0.736266018520009	0.879123604202996	TCOF1/NCL/PWP1	3
GO:0016242	negative regulation of macroautophagy	3/2053	34/18722	0.736266018520009	0.879123604202996	LRRK2/HMOX1/QSOX1	3
GO:0035137	hindlimb morphogenesis	3/2053	34/18722	0.736266018520009	0.879123604202996	NOTCH1/TBX3/GPC3	3
GO:0035909	aorta morphogenesis	3/2053	34/18722	0.736266018520009	0.879123604202996	ENG/NOTCH1/SOX4	3
GO:0048536	spleen development	3/2053	34/18722	0.736266018520009	0.879123604202996	PRKDC/PBX1/PKN1	3
GO:2000352	negative regulation of endothelial cell apoptotic process	3/2053	34/18722	0.736266018520009	0.879123604202996	TNFAIP3/ICAM1/GATA3	3
GO:0006906	vesicle fusion	10/2053	106/18722	0.738501897145179	0.881428515562244	CORO1A/STX11/SAMD9/CHP1/SPHK1/SYT7/STX10/VAV3/EEA1/STX6	10
GO:0015914	phospholipid transport	9/2053	96/18722	0.73871123727797	0.881428515562244	NPC2/DBI/P2RX7/APOC1/TRIAP1/PLSCR1/TMEM30B/KCNN4/PITPNB	9
GO:0042158	lipoprotein biosynthetic process	9/2053	96/18722	0.73871123727797	0.881428515562244	GLUL/DBI/ZDHHC12/GPAA1/PGAP2/SVIP/NMT1/DPM2/WIPI2	9
GO:0006720	isoprenoid metabolic process	11/2053	116/18722	0.738784000793754	0.881428515562244	NPC2/EGFR/LRP2/FDPS/ADH5/AKR1B1/ALDH1A1/SCPEP1/FDFT1/PMVK/DPM2	11
GO:1903510	mucopolysaccharide metabolic process	8/2053	86/18722	0.739585340977196	0.882088258761367	CD44/TGFB1/ITIH5/IL1B/CHPF/CHST15/CHST14/DSE	8
GO:0008654	phospholipid biosynthetic process	25/2053	253/18722	0.739631004971406	0.882088258761367	LPCAT2/ISYNA1/SOCS3/FDPS/AGPAT2/CHPT1/CHP1/GPAA1/PGAP2/FABP5/SH3YL1/PLSCR1/PMVK/IMPA2/IDH1/DGKD/INPP5D/CDS1/SLC44A1/PISD/CDIPT/HEXB/SLC44A2/PDGFA/DPM2	25
GO:0098876	vesicle-mediated transport to the plasma membrane	13/2053	136/18722	0.740371762431698	0.882796219115698	SORL1/VAMP5/KRT18/NSG1/CSK/GOLGA4/SNX4/ANK3/SPTBN1/GOPC/COMMD1/CLSTN1/STX6	13
GO:0071426	ribonucleoprotein complex export from nucleus	7/2053	76/18722	0.741380760216788	0.883823675998555	RAN/HHEX/NPM1/NUP214/TPR/HNRNPA2B1/PABPN1	7
GO:0048546	digestive tract morphogenesis	4/2053	45/18722	0.742127811202227	0.88398075686516	NOTCH1/AHI1/GLI3/ID2	4
GO:0060119	inner ear receptor cell development	4/2053	45/18722	0.742127811202227	0.88398075686516	SOD1/KCNQ1/TRIOBP/MYO7A	4
GO:2000272	negative regulation of signaling receptor activity	6/2053	66/18722	0.744493953477309	0.88398075686516	LILRB4/TNF/LRPAP1/VPS25/PPARG/NCAPG2	6
GO:0003002	regionalization	33/2053	331/18722	0.745859559874841	0.88398075686516	MAFB/MEF2C/ITGAM/LRP2/WLS/ADGRG1/C3/PRKDC/NRP2/NOTCH1/HHEX/NR2F2/LFNG/C1QA/HSPB11/BTG2/NRP1/ISL1/NOTCH2/AHI1/PBX1/LRP5/BHLHE40/TRA2B/GLI3/FOXC1/BHLHE41/BASP1/TBX3/IRX2/COBL/GPC3/XRCC2	33
GO:0030301	cholesterol transport	11/2053	117/18722	0.748918733917034	0.88398075686516	TSPO/MSR1/NPC2/CD36/NFKBIA/TREM2/APOC1/SYT7/LIMA1/LDLRAP1/PPARG	11
GO:0010927	cellular component assembly involved in morphogenesis	10/2053	107/18722	0.749083106031151	0.88398075686516	CD9/TLR2/CSRP2/MEF2A/DAG1/ITGB1/ITGB4/KRT8/OBSL1/GPC1	10
GO:0035270	endocrine system development	12/2053	127/18722	0.749169106685036	0.88398075686516	TSPO/CDH1/IL6R/ISL1/RHEB/SOX4/GATA3/PBX1/CDK6/ARID5B/BAD/MDK	12
GO:0010658	striated muscle cell apoptotic process	5/2053	56/18722	0.749572345349265	0.88398075686516	JAK2/BMP7/CAMK2D/BNIP3/MDK	5
GO:0015800	acidic amino acid transport	5/2053	56/18722	0.749572345349265	0.88398075686516	ITGB1/LRRC8C/GJA1/SLC6A6/SLC1A3	5
GO:0042733	embryonic digit morphogenesis	5/2053	56/18722	0.749572345349265	0.88398075686516	NOTCH1/HDAC2/LRP5/GLI3/TBX3	5
GO:0070534	protein K63-linked ubiquitination	5/2053	56/18722	0.749572345349265	0.88398075686516	UBE2T/UBE2S/RNF8/PRPF19/UBE2N	5
GO:0098781	ncRNA transcription	5/2053	56/18722	0.749572345349265	0.88398075686516	POLR2L/TCOF1/NCL/ELL2/PWP1	5
GO:0007586	digestion	13/2053	137/18722	0.749740131599437	0.88398075686516	TYMP/SNX10/TLR4/CD36/SGK1/KCNQ1/HAMP/HRH2/VDR/KCNN4/EZR/LIMA1/EPB41	13
GO:0043255	regulation of carbohydrate biosynthetic process	9/2053	97/18722	0.749792153766347	0.88398075686516	PLEK/TGFB1/FBP1/PGP/PTAFR/PTK2B/SLC35B4/DDB1/INSR	9
GO:0000012	single strand break repair	1/2053	12/18722	0.751972963839963	0.88398075686516	PARP1	1
GO:0000491	small nucleolar ribonucleoprotein complex assembly	1/2053	12/18722	0.751972963839963	0.88398075686516	SNU13	1
GO:0001976	nervous system process involved in regulation of systemic arterial blood pressure	1/2053	12/18722	0.751972963839963	0.88398075686516	SOD2	1
GO:0002182	cytoplasmic translational elongation	1/2053	12/18722	0.751972963839963	0.88398075686516	RPLP2	1
GO:0003353	positive regulation of cilium movement	1/2053	12/18722	0.751972963839963	0.88398075686516	DEFB1	1
GO:0006285	base-excision repair, AP site formation	1/2053	12/18722	0.751972963839963	0.88398075686516	UNG	1
GO:0006787	porphyrin-containing compound catabolic process	1/2053	12/18722	0.751972963839963	0.88398075686516	HMOX1	1
GO:0007320	insemination	1/2053	12/18722	0.751972963839963	0.88398075686516	SLC6A4	1
GO:0010623	programmed cell death involved in cell development	1/2053	12/18722	0.751972963839963	0.88398075686516	PRKDC	1
GO:0015780	nucleotide-sugar transmembrane transport	1/2053	12/18722	0.751972963839963	0.88398075686516	SLC35B4	1
GO:0016188	synaptic vesicle maturation	1/2053	12/18722	0.751972963839963	0.88398075686516	PICALM	1
GO:0019627	urea metabolic process	1/2053	12/18722	0.751972963839963	0.88398075686516	ASS1	1
GO:0021527	spinal cord association neuron differentiation	1/2053	12/18722	0.751972963839963	0.88398075686516	LMO4	1
GO:0021936	regulation of cerebellar granule cell precursor proliferation	1/2053	12/18722	0.751972963839963	0.88398075686516	SLC6A4	1
GO:0031126	sno(s)RNA 3'-end processing	1/2053	12/18722	0.751972963839963	0.88398075686516	FBL	1
GO:0032096	negative regulation of response to food	1/2053	12/18722	0.751972963839963	0.88398075686516	NENF	1
GO:0032099	negative regulation of appetite	1/2053	12/18722	0.751972963839963	0.88398075686516	NENF	1
GO:0032105	negative regulation of response to extracellular stimulus	1/2053	12/18722	0.751972963839963	0.88398075686516	NENF	1
GO:0032108	negative regulation of response to nutrient levels	1/2053	12/18722	0.751972963839963	0.88398075686516	NENF	1
GO:0032780	negative regulation of ATPase activity	1/2053	12/18722	0.751972963839963	0.88398075686516	CNN3	1
GO:0033015	tetrapyrrole catabolic process	1/2053	12/18722	0.751972963839963	0.88398075686516	HMOX1	1
GO:0033079	immature T cell proliferation	1/2053	12/18722	0.751972963839963	0.88398075686516	IL1B	1
GO:0033629	negative regulation of cell adhesion mediated by integrin	1/2053	12/18722	0.751972963839963	0.88398075686516	JAM3	1
GO:0034086	maintenance of sister chromatid cohesion	1/2053	12/18722	0.751972963839963	0.88398075686516	DSCC1	1
GO:0034088	maintenance of mitotic sister chromatid cohesion	1/2053	12/18722	0.751972963839963	0.88398075686516	DSCC1	1
GO:0035739	CD4-positive, alpha-beta T cell proliferation	1/2053	12/18722	0.751972963839963	0.88398075686516	LGALS9	1
GO:0035933	glucocorticoid secretion	1/2053	12/18722	0.751972963839963	0.88398075686516	KCNQ1	1
GO:0038203	TORC2 signaling	1/2053	12/18722	0.751972963839963	0.88398075686516	NCKAP1L	1
GO:0043471	regulation of cellular carbohydrate catabolic process	1/2053	12/18722	0.751972963839963	0.88398075686516	HMGB1	1
GO:0045117	azole transmembrane transport	1/2053	12/18722	0.751972963839963	0.88398075686516	SLC19A3	1
GO:0046322	negative regulation of fatty acid oxidation	1/2053	12/18722	0.751972963839963	0.88398075686516	ACADVL	1
GO:0046541	saliva secretion	1/2053	12/18722	0.751972963839963	0.88398075686516	KCNN4	1
GO:0046831	regulation of RNA export from nucleus	1/2053	12/18722	0.751972963839963	0.88398075686516	TPR	1
GO:0048548	regulation of pinocytosis	1/2053	12/18722	0.751972963839963	0.88398075686516	PPT1	1
GO:0051013	microtubule severing	1/2053	12/18722	0.751972963839963	0.88398075686516	FIGNL1	1
GO:0051549	positive regulation of keratinocyte migration	1/2053	12/18722	0.751972963839963	0.88398075686516	HBEGF	1
GO:0051583	dopamine uptake involved in synaptic transmission	1/2053	12/18722	0.751972963839963	0.88398075686516	PARK7	1
GO:0051934	catecholamine uptake involved in synaptic transmission	1/2053	12/18722	0.751972963839963	0.88398075686516	PARK7	1
GO:0060123	regulation of growth hormone secretion	1/2053	12/18722	0.751972963839963	0.88398075686516	SERP1	1
GO:0060221	retinal rod cell differentiation	1/2053	12/18722	0.751972963839963	0.88398075686516	PTN	1
GO:0060442	branching involved in prostate gland morphogenesis	1/2053	12/18722	0.751972963839963	0.88398075686516	BMP7	1
GO:0060601	lateral sprouting from an epithelium	1/2053	12/18722	0.751972963839963	0.88398075686516	BMP7	1
GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	1/2053	12/18722	0.751972963839963	0.88398075686516	GLI3	1
GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	1/2053	12/18722	0.751972963839963	0.88398075686516	RGS2	1
GO:0061430	bone trabecula morphogenesis	1/2053	12/18722	0.751972963839963	0.88398075686516	FBN2	1
GO:0070170	regulation of tooth mineralization	1/2053	12/18722	0.751972963839963	0.88398075686516	TFAP2A	1
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	1/2053	12/18722	0.751972963839963	0.88398075686516	BRD4	1
GO:0071257	cellular response to electrical stimulus	1/2053	12/18722	0.751972963839963	0.88398075686516	SLC9A1	1
GO:0071941	nitrogen cycle metabolic process	1/2053	12/18722	0.751972963839963	0.88398075686516	ASS1	1
GO:0086067	AV node cell to bundle of His cell communication	1/2053	12/18722	0.751972963839963	0.88398075686516	GJA5	1
GO:0090385	phagosome-lysosome fusion	1/2053	12/18722	0.751972963839963	0.88398075686516	SYT7	1
GO:0097152	mesenchymal cell apoptotic process	1/2053	12/18722	0.751972963839963	0.88398075686516	BMP7	1
GO:0099151	regulation of postsynaptic density assembly	1/2053	12/18722	0.751972963839963	0.88398075686516	ABI3	1
GO:1902950	regulation of dendritic spine maintenance	1/2053	12/18722	0.751972963839963	0.88398075686516	HOMER1	1
GO:1903909	regulation of receptor clustering	1/2053	12/18722	0.751972963839963	0.88398075686516	PTN	1
GO:2000317	negative regulation of T-helper 17 type immune response	1/2053	12/18722	0.751972963839963	0.88398075686516	IL27RA	1
GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation	1/2053	12/18722	0.751972963839963	0.88398075686516	LGALS9	1
GO:0071166	ribonucleoprotein complex localization	7/2053	77/18722	0.753668388985626	0.884590707941872	RAN/HHEX/NPM1/NUP214/TPR/HNRNPA2B1/PABPN1	7
GO:0000460	maturation of 5.8S rRNA	3/2053	35/18722	0.754261010305103	0.884590707941872	RPS21/PRKDC/EXOSC8	3
GO:0003298	physiological muscle hypertrophy	3/2053	35/18722	0.754261010305103	0.884590707941872	HAMP/PARP2/RGS2	3
GO:0003301	physiological cardiac muscle hypertrophy	3/2053	35/18722	0.754261010305103	0.884590707941872	HAMP/PARP2/RGS2	3
GO:0010664	negative regulation of striated muscle cell apoptotic process	3/2053	35/18722	0.754261010305103	0.884590707941872	JAK2/BMP7/MDK	3
GO:0031076	embryonic camera-type eye development	3/2053	35/18722	0.754261010305103	0.884590707941872	RARA/BMP7/TFAP2A	3
GO:0045922	negative regulation of fatty acid metabolic process	3/2053	35/18722	0.754261010305103	0.884590707941872	BRCA1/ACADVL/APOC1	3
GO:0046471	phosphatidylglycerol metabolic process	3/2053	35/18722	0.754261010305103	0.884590707941872	PHB2/STOML2/DNAJC19	3
GO:0061049	cell growth involved in cardiac muscle cell development	3/2053	35/18722	0.754261010305103	0.884590707941872	HAMP/PARP2/RGS2	3
GO:0090181	regulation of cholesterol metabolic process	3/2053	35/18722	0.754261010305103	0.884590707941872	SOD1/ACADVL/LDLRAP1	3
GO:0097502	mannosylation	3/2053	35/18722	0.754261010305103	0.884590707941872	TMTC3/DPM2/ALG8	3
GO:1905508	protein localization to microtubule organizing center	3/2053	35/18722	0.754261010305103	0.884590707941872	SNX10/GOLGB1/CCDC14	3
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2/2053	24/18722	0.756622608134441	0.884766253908916	RPS21/EXOSC8	2
GO:0001702	gastrulation with mouth forming second	2/2053	24/18722	0.756622608134441	0.884766253908916	AMOT/LRP5	2
GO:0001779	natural killer cell differentiation	2/2053	24/18722	0.756622608134441	0.884766253908916	PTPRC/PBX1	2
GO:0002021	response to dietary excess	2/2053	24/18722	0.756622608134441	0.884766253908916	SORL1/ADRB1	2
GO:0044062	regulation of excretion	2/2053	24/18722	0.756622608134441	0.884766253908916	COMT/GNAI2	2
GO:0048011	neurotrophin TRK receptor signaling pathway	2/2053	24/18722	0.756622608134441	0.884766253908916	DDIT4/BCAR1	2
GO:0048641	regulation of skeletal muscle tissue development	2/2053	24/18722	0.756622608134441	0.884766253908916	TGFB1/MEF2C	2
GO:0050687	negative regulation of defense response to virus	2/2053	24/18722	0.756622608134441	0.884766253908916	FGL2/C1QBP	2
GO:0051905	establishment of pigment granule localization	2/2053	24/18722	0.756622608134441	0.884766253908916	MYO5A/MYO7A	2
GO:0051923	sulfation	2/2053	24/18722	0.756622608134441	0.884766253908916	SULT1A1/TPST2	2
GO:0060479	lung cell differentiation	2/2053	24/18722	0.756622608134441	0.884766253908916	KLF2/YAP1	2
GO:0060571	morphogenesis of an epithelial fold	2/2053	24/18722	0.756622608134441	0.884766253908916	BMP7/LUZP1	2
GO:0071676	negative regulation of mononuclear cell migration	2/2053	24/18722	0.756622608134441	0.884766253908916	DUSP1/IL27RA	2
GO:1903861	positive regulation of dendrite extension	2/2053	24/18722	0.756622608134441	0.884766253908916	CXCR4/ITSN2	2
GO:2000353	positive regulation of endothelial cell apoptotic process	2/2053	24/18722	0.756622608134441	0.884766253908916	ITGA4/RGCC	2
GO:0032890	regulation of organic acid transport	6/2053	67/18722	0.75752085050878	0.88505390255289	IL1B/SYK/ITGB1/FIS1/RGS2/PTGES	6
GO:0050435	amyloid-beta metabolic process	6/2053	67/18722	0.75752085050878	0.88505390255289	SORL1/TNF/MME/EFNA1/IFNGR1/PICALM	6
GO:0031648	protein destabilization	4/2053	46/18722	0.757753649569032	0.88505390255289	PRKDC/CTSH/SIAH1/MYLIP	4
GO:0034198	cellular response to amino acid starvation	4/2053	46/18722	0.757753649569032	0.88505390255289	UCP2/EIF2AK4/CDKN1A/ATF3	4
GO:0043462	regulation of ATPase activity	4/2053	46/18722	0.757753649569032	0.88505390255289	DNAJC9/CNN3/PFN1/SNRNP70	4
GO:0072599	establishment of protein localization to endoplasmic reticulum	4/2053	46/18722	0.757753649569032	0.88505390255289	HSPA5/SPCS2/SEC63/SGTB	4
GO:0050804	modulation of chemical synaptic transmission	44/2053	439/18722	0.760451470234752	0.887966985158892	TYROBP/SRGN/LILRB2/MEF2C/EGFR/JAK2/LRRK2/RETN/CDH1/TNF/IL1B/APP/CCR2/ARRB2/GLUL/NSG1/MME/RARA/ITGB1/MCTP1/PTK2B/PNKD/ZDHHC12/PRKCB/CX3CR1/GNAI2/SLC6A6/HRAS/SLC6A4/STAU1/ABR/SYT7/STAT3/RAP1A/NRGN/GNAI1/EIF2AK4/CHRNA5/PLK2/PTN/AKAP9/CLSTN1/HOMER1/SLC1A3	44
GO:0043473	pigmentation	9/2053	98/18722	0.760543722788591	0.887966985158892	ZEB2/RAB32/MEF2C/LYST/CD63/GNA11/GLI3/MYO5A/MYO7A	9
GO:0034205	amyloid-beta formation	5/2053	57/18722	0.763456902943406	0.891194828338606	SORL1/TNF/EFNA1/IFNGR1/PICALM	5
GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	7/2053	78/18722	0.765532084606862	0.893443397712736	FLNA/PSAP/RGS1/MARCO/GNAI2/GNAI1/RGS2	7
GO:0000045	autophagosome assembly	9/2053	99/18722	0.77096610454815	0.893735419882493	LRRK2/VMP1/RALB/UBXN2A/TCIRG1/ATG16L2/GABARAP/TMEM41B/WIPI2	9
GO:0021549	cerebellum development	9/2053	99/18722	0.77096610454815	0.893735419882493	AIF1/HSPA5/EZH2/UQCRQ/HNRNPD/RERE/FOXC1/MDK/PTN	9
GO:0003352	regulation of cilium movement	3/2053	36/18722	0.771252880753853	0.893735419882493	CATSPER1/CFAP20/DEFB1	3
GO:0043949	regulation of cAMP-mediated signaling	3/2053	36/18722	0.771252880753853	0.893735419882493	PDE4A/GNAI1/RGS2	3
GO:0044060	regulation of endocrine process	3/2053	36/18722	0.771252880753853	0.893735419882493	RETN/GJA1/C1QTNF1	3
GO:0044743	protein transmembrane import into intracellular organelle	3/2053	36/18722	0.771252880753853	0.893735419882493	HSPD1/TOMM40/DNAJC19	3
GO:0070873	regulation of glycogen metabolic process	3/2053	36/18722	0.771252880753853	0.893735419882493	HMGB1/PHLDA2/INSR	3
GO:0086010	membrane depolarization during action potential	3/2053	36/18722	0.771252880753853	0.893735419882493	SLC8A1/ANK3/PTPN3	3
GO:0001754	eye photoreceptor cell differentiation	4/2053	47/18722	0.77263569874562	0.893735419882493	VEGFA/STAT3/PTN/MYO7A	4
GO:0045332	phospholipid translocation	4/2053	47/18722	0.77263569874562	0.893735419882493	P2RX7/PLSCR1/TMEM30B/KCNN4	4
GO:1903170	negative regulation of calcium ion transmembrane transport	4/2053	47/18722	0.77263569874562	0.893735419882493	CALM2/C4orf3/VDAC1/YWHAE	4
GO:0006658	phosphatidylserine metabolic process	2/2053	25/18722	0.776587115706176	0.893735419882493	PLSCR1/SERINC2	2
GO:0010560	positive regulation of glycoprotein biosynthetic process	2/2053	25/18722	0.776587115706176	0.893735419882493	PAWR/CHP1	2
GO:0010954	positive regulation of protein processing	2/2053	25/18722	0.776587115706176	0.893735419882493	ADAM8/BAG2	2
GO:0032104	regulation of response to extracellular stimulus	2/2053	25/18722	0.776587115706176	0.893735419882493	TRIM24/NENF	2
GO:0032107	regulation of response to nutrient levels	2/2053	25/18722	0.776587115706176	0.893735419882493	TRIM24/NENF	2
GO:0035336	long-chain fatty-acyl-CoA metabolic process	2/2053	25/18722	0.776587115706176	0.893735419882493	TECR/ACSL4	2
GO:0045109	intermediate filament organization	2/2053	25/18722	0.776587115706176	0.893735419882493	VIM/DSP	2
GO:0045324	late endosome to vacuole transport	2/2053	25/18722	0.776587115706176	0.893735419882493	CHMP4C/VPS25	2
GO:0046835	carbohydrate phosphorylation	2/2053	25/18722	0.776587115706176	0.893735419882493	HK3/HK2	2
GO:0048596	embryonic camera-type eye morphogenesis	2/2053	25/18722	0.776587115706176	0.893735419882493	BMP7/TFAP2A	2
GO:0060740	prostate gland epithelium morphogenesis	2/2053	25/18722	0.776587115706176	0.893735419882493	BMP7/NOTCH1	2
GO:0099560	synaptic membrane adhesion	2/2053	25/18722	0.776587115706176	0.893735419882493	PTPRF/MAPK14	2
GO:1904385	cellular response to angiotensin	2/2053	25/18722	0.776587115706176	0.893735419882493	CYBA/CDC6	2
GO:1904753	negative regulation of vascular associated smooth muscle cell migration	2/2053	25/18722	0.776587115706176	0.893735419882493	MEF2C/RHOA	2
GO:1904754	positive regulation of vascular associated smooth muscle cell migration	2/2053	25/18722	0.776587115706176	0.893735419882493	DOCK4/ADAMTS1	2
GO:0010559	regulation of glycoprotein biosynthetic process	5/2053	58/18722	0.776750902439874	0.893735419882493	HBEGF/PAWR/ITM2C/CHP1/AGO2	5
GO:0044380	protein localization to cytoskeleton	5/2053	58/18722	0.776750902439874	0.893735419882493	SNX10/GOLGB1/KIF20B/CCDC14/TTK	5
GO:0097035	regulation of membrane lipid distribution	5/2053	58/18722	0.776750902439874	0.893735419882493	P2RX7/TRIAP1/PLSCR1/TMEM30B/KCNN4	5
GO:0071774	response to fibroblast growth factor	11/2053	120/18722	0.777706665264094	0.893735419882493	CD44/ZFP36/ZFP36L2/ZFP36L1/NR4A1/CXCL8/SULF2/GATA3/GCLM/SHCBP1/GPC1	11
GO:0009566	fertilization	18/2053	190/18722	0.778323359973473	0.893735419882493	CD9/LHFPL2/CD46/CDK1/NR2F2/SPESP1/ALDOA/SLIRP/TCP1/FOLR1/SNU13/CCT2/PITHD1/ABHD2/PARK7/CCT4/CCT8/HEXB	18
GO:0090174	organelle membrane fusion	10/2053	110/18722	0.779049153128339	0.893735419882493	CORO1A/STX11/SAMD9/CHP1/SPHK1/SYT7/STX10/VAV3/EEA1/STX6	10
GO:0001682	tRNA 5'-leader removal	1/2053	13/18722	0.77918833023422	0.893735419882493	POP7	1
GO:0001768	establishment of T cell polarity	1/2053	13/18722	0.77918833023422	0.893735419882493	DOCK2	1
GO:0001778	plasma membrane repair	1/2053	13/18722	0.77918833023422	0.893735419882493	SYT7	1
GO:0001886	endothelial cell morphogenesis	1/2053	13/18722	0.77918833023422	0.893735419882493	MET	1
GO:0001973	G protein-coupled adenosine receptor signaling pathway	1/2053	13/18722	0.77918833023422	0.893735419882493	GNAI2	1
GO:0003334	keratinocyte development	1/2053	13/18722	0.77918833023422	0.893735419882493	PALLD	1
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	1/2053	13/18722	0.77918833023422	0.893735419882493	STAT1	1
GO:0006995	cellular response to nitrogen starvation	1/2053	13/18722	0.77918833023422	0.893735419882493	GABARAP	1
GO:0014029	neural crest formation	1/2053	13/18722	0.77918833023422	0.893735419882493	TCOF1	1
GO:0015791	polyol transport	1/2053	13/18722	0.77918833023422	0.893735419882493	AQP9	1
GO:0015801	aromatic amino acid transport	1/2053	13/18722	0.77918833023422	0.893735419882493	SLC3A2	1
GO:0015816	glycine transport	1/2053	13/18722	0.77918833023422	0.893735419882493	RGS2	1
GO:0016056	rhodopsin mediated signaling pathway	1/2053	13/18722	0.77918833023422	0.893735419882493	NMT1	1
GO:0016078	tRNA catabolic process	1/2053	13/18722	0.77918833023422	0.893735419882493	EXOSC8	1
GO:0016246	RNA interference	1/2053	13/18722	0.77918833023422	0.893735419882493	AGO2	1
GO:0018095	protein polyglutamylation	1/2053	13/18722	0.77918833023422	0.893735419882493	CFAP20	1
GO:0019336	phenol-containing compound catabolic process	1/2053	13/18722	0.77918833023422	0.893735419882493	COMT	1
GO:0019755	one-carbon compound transport	1/2053	13/18722	0.77918833023422	0.893735419882493	AQP9	1
GO:0021681	cerebellar granular layer development	1/2053	13/18722	0.77918833023422	0.893735419882493	MDK	1
GO:0021859	pyramidal neuron differentiation	1/2053	13/18722	0.77918833023422	0.893735419882493	UQCRQ	1
GO:0032230	positive regulation of synaptic transmission, GABAergic	1/2053	13/18722	0.77918833023422	0.893735419882493	ZDHHC12	1
GO:0032352	positive regulation of hormone metabolic process	1/2053	13/18722	0.77918833023422	0.893735419882493	GATA3	1
GO:0033689	negative regulation of osteoblast proliferation	1/2053	13/18722	0.77918833023422	0.893735419882493	ATRAID	1
GO:0033700	phospholipid efflux	1/2053	13/18722	0.77918833023422	0.893735419882493	APOC1	1
GO:0034309	primary alcohol biosynthetic process	1/2053	13/18722	0.77918833023422	0.893735419882493	PARK7	1
GO:0034497	protein localization to phagophore assembly site	1/2053	13/18722	0.77918833023422	0.893735419882493	WIPI2	1
GO:0035588	G protein-coupled purinergic receptor signaling pathway	1/2053	13/18722	0.77918833023422	0.893735419882493	GNAI2	1
GO:0035845	photoreceptor cell outer segment organization	1/2053	13/18722	0.77918833023422	0.893735419882493	AHI1	1
GO:0042362	fat-soluble vitamin biosynthetic process	1/2053	13/18722	0.77918833023422	0.893735419882493	TNF	1
GO:0043562	cellular response to nitrogen levels	1/2053	13/18722	0.77918833023422	0.893735419882493	GABARAP	1
GO:0043928	exonucleolytic catabolism of deadenylated mRNA	1/2053	13/18722	0.77918833023422	0.893735419882493	EXOSC8	1
GO:0046512	sphingosine biosynthetic process	1/2053	13/18722	0.77918833023422	0.893735419882493	SPHK1	1
GO:0046520	sphingoid biosynthetic process	1/2053	13/18722	0.77918833023422	0.893735419882493	SPHK1	1
GO:0048070	regulation of developmental pigmentation	1/2053	13/18722	0.77918833023422	0.893735419882493	ZEB2	1
GO:0048207	vesicle targeting, rough ER to cis-Golgi	1/2053	13/18722	0.77918833023422	0.893735419882493	TFG	1
GO:0048208	COPII vesicle coating	1/2053	13/18722	0.77918833023422	0.893735419882493	TFG	1
GO:0048820	hair follicle maturation	1/2053	13/18722	0.77918833023422	0.893735419882493	FERMT1	1
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	1/2053	13/18722	0.77918833023422	0.893735419882493	CALM2	1
GO:0051956	negative regulation of amino acid transport	1/2053	13/18722	0.77918833023422	0.893735419882493	RGS2	1
GO:0061469	regulation of type B pancreatic cell proliferation	1/2053	13/18722	0.77918833023422	0.893735419882493	NR4A1	1
GO:0071027	nuclear RNA surveillance	1/2053	13/18722	0.77918833023422	0.893735419882493	EXOSC8	1
GO:0071028	nuclear mRNA surveillance	1/2053	13/18722	0.77918833023422	0.893735419882493	EXOSC8	1
GO:0090161	Golgi ribbon formation	1/2053	13/18722	0.77918833023422	0.893735419882493	STX6	1
GO:0097154	GABAergic neuron differentiation	1/2053	13/18722	0.77918833023422	0.893735419882493	RAC3	1
GO:0099150	regulation of postsynaptic specialization assembly	1/2053	13/18722	0.77918833023422	0.893735419882493	ABI3	1
GO:0106070	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	1/2053	13/18722	0.77918833023422	0.893735419882493	GNAI2	1
GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity	1/2053	13/18722	0.77918833023422	0.893735419882493	IARS2	1
GO:0120305	regulation of pigmentation	1/2053	13/18722	0.77918833023422	0.893735419882493	ZEB2	1
GO:1900452	regulation of long-term synaptic depression	1/2053	13/18722	0.77918833023422	0.893735419882493	LILRB2	1
GO:1901387	positive regulation of voltage-gated calcium channel activity	1/2053	13/18722	0.77918833023422	0.893735419882493	KCNE3	1
GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	1/2053	13/18722	0.77918833023422	0.893735419882493	TMSB4X	1
GO:1904995	negative regulation of leukocyte adhesion to vascular endothelial cell	1/2053	13/18722	0.77918833023422	0.893735419882493	KLF4	1
GO:1905064	negative regulation of vascular associated smooth muscle cell differentiation	1/2053	13/18722	0.77918833023422	0.893735419882493	DNMT1	1
GO:1905203	regulation of connective tissue replacement	1/2053	13/18722	0.77918833023422	0.893735419882493	RUNX1	1
GO:1905244	regulation of modification of synaptic structure	1/2053	13/18722	0.77918833023422	0.893735419882493	RHOA	1
GO:1905939	regulation of gonad development	1/2053	13/18722	0.77918833023422	0.893735419882493	RETN	1
GO:1990403	embryonic brain development	1/2053	13/18722	0.77918833023422	0.893735419882493	TRA2B	1
GO:2001023	regulation of response to drug	1/2053	13/18722	0.77918833023422	0.893735419882493	ADIRF	1
GO:0060079	excitatory postsynaptic potential	9/2053	100/18722	0.781060247883835	0.895711293444765	MEF2C/LRRK2/APP/ARRB2/PTK2B/P2RX7/SLC29A1/CHRNB1/CHRNA5	9
GO:0051650	establishment of vesicle localization	15/2053	161/18722	0.784526311544826	0.899514211593532	MYO1F/MYO1G/LRRK2/ITGA4/TMED9/CHP1/MYO1C/FNBP1L/TCIRG1/PICALM/MYO5A/TFG/CCDC186/ACTN4/MYO7A	15
GO:0006111	regulation of gluconeogenesis	4/2053	48/18722	0.786788261276554	0.901763050173701	FBP1/PGP/SLC35B4/DDB1	4
GO:0120009	intermembrane lipid transfer	4/2053	48/18722	0.786788261276554	0.901763050173701	TSPO/NPC2/TRIAP1/PITPNB	4
GO:0016202	regulation of striated muscle tissue development	3/2053	37/18722	0.787270476884764	0.901798942594232	TGFB1/MEF2C/CENPF	3
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	3/2053	37/18722	0.787270476884764	0.901798942594232	SULF2/GATA3/GPC1	3
GO:0071542	dopaminergic neuron differentiation	3/2053	37/18722	0.787270476884764	0.901798942594232	VEGFA/NR4A2/MANF	3
GO:0006406	mRNA export from nucleus	5/2053	59/18722	0.789462837028479	0.90396508056696	HHEX/NUP214/TPR/HNRNPA2B1/PABPN1	5
GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus	5/2053	59/18722	0.789462837028479	0.90396508056696	HHEX/NUP214/TPR/HNRNPA2B1/PABPN1	5
GO:0051963	regulation of synapse assembly	9/2053	101/18722	0.79082783859112	0.90535528172996	MEF2C/TLR2/ABI3/APP/SEMA4A/TPBG/DLG5/EIF4G1/CLSTN1	9
GO:0007214	gamma-aminobutyric acid signaling pathway	2/2053	26/18722	0.79510218458081	0.907475963607963	GNAI2/GABRE	2
GO:0021952	central nervous system projection neuron axonogenesis	2/2053	26/18722	0.79510218458081	0.907475963607963	NR4A2/C12orf57	2
GO:0045745	positive regulation of G protein-coupled receptor signaling pathway	2/2053	26/18722	0.79510218458081	0.907475963607963	C3/PHB	2
GO:0051875	pigment granule localization	2/2053	26/18722	0.79510218458081	0.907475963607963	MYO5A/MYO7A	2
GO:0070977	bone maturation	2/2053	26/18722	0.79510218458081	0.907475963607963	SNX10/RHOA	2
GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	2/2053	26/18722	0.79510218458081	0.907475963607963	GNAI2/ADRB1	2
GO:0072273	metanephric nephron morphogenesis	2/2053	26/18722	0.79510218458081	0.907475963607963	STAT1/LGR4	2
GO:0099637	neurotransmitter receptor transport	2/2053	26/18722	0.79510218458081	0.907475963607963	NSG1/CLSTN1	2
GO:1902186	regulation of viral release from host cell	2/2053	26/18722	0.79510218458081	0.907475963607963	DDB1/TRIM28	2
GO:0006778	porphyrin-containing compound metabolic process	4/2053	49/18722	0.800227915816657	0.907475963607963	TSPO/HMOX1/EIF2AK1/ALAD	4
GO:0009994	oocyte differentiation	4/2053	49/18722	0.800227915816657	0.907475963607963	PTK2B/LGR5/FBXO5/BRCA2	4
GO:1904752	regulation of vascular associated smooth muscle cell migration	4/2053	49/18722	0.800227915816657	0.907475963607963	MEF2C/DOCK4/ADAMTS1/RHOA	4
GO:1990928	response to amino acid starvation	4/2053	49/18722	0.800227915816657	0.907475963607963	UCP2/EIF2AK4/CDKN1A/ATF3	4
GO:0001505	regulation of neurotransmitter levels	20/2053	213/18722	0.80044200072846	0.907475963607963	MEF2C/LRRK2/STXBP2/SLC38A1/STX11/ITGB1/MCTP1/NR4A1/COMT/PNKD/SLC29A1/PRKCB/PPT1/SLC6A4/SYT7/RAP1A/PARK7/CHRNA5/GCHFR/SLC1A3	20
GO:0000578	embryonic axis specification	3/2053	38/18722	0.802345594940646	0.907475963607963	BASP1/TBX3/COBL	3
GO:0010719	negative regulation of epithelial to mesenchymal transition	3/2053	38/18722	0.802345594940646	0.907475963607963	LDLRAD4/GATA3/EFNA1	3
GO:0032941	secretion by tissue	3/2053	38/18722	0.802345594940646	0.907475963607963	CYBA/EGFR/KCNN4	3
GO:0046329	negative regulation of JNK cascade	3/2053	38/18722	0.802345594940646	0.907475963607963	GSTP1/MARVELD3/SIRPA	3
GO:0001711	endodermal cell fate commitment	1/2053	14/18722	0.803418719780917	0.907475963607963	RTF1	1
GO:0001767	establishment of lymphocyte polarity	1/2053	14/18722	0.803418719780917	0.907475963607963	DOCK2	1
GO:0001921	positive regulation of receptor recycling	1/2053	14/18722	0.803418719780917	0.907475963607963	NSG1	1
GO:0003214	cardiac left ventricle morphogenesis	1/2053	14/18722	0.803418719780917	0.907475963607963	NOTCH1	1
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	1/2053	14/18722	0.803418719780917	0.907475963607963	SERPINH1	1
GO:0006047	UDP-N-acetylglucosamine metabolic process	1/2053	14/18722	0.803418719780917	0.907475963607963	GFPT1	1
GO:0006465	signal peptide processing	1/2053	14/18722	0.803418719780917	0.907475963607963	SPCS2	1
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	1/2053	14/18722	0.803418719780917	0.907475963607963	VPS25	1
GO:0009214	cyclic nucleotide catabolic process	1/2053	14/18722	0.803418719780917	0.907475963607963	PDE4A	1
GO:0010839	negative regulation of keratinocyte proliferation	1/2053	14/18722	0.803418719780917	0.907475963607963	VDR	1
GO:0010872	regulation of cholesterol esterification	1/2053	14/18722	0.803418719780917	0.907475963607963	APOC1	1
GO:0010896	regulation of triglyceride catabolic process	1/2053	14/18722	0.803418719780917	0.907475963607963	SORL1	1
GO:0014874	response to stimulus involved in regulation of muscle adaptation	1/2053	14/18722	0.803418719780917	0.907475963607963	DAG1	1
GO:0015812	gamma-aminobutyric acid transport	1/2053	14/18722	0.803418719780917	0.907475963607963	SLC6A6	1
GO:0022038	corpus callosum development	1/2053	14/18722	0.803418719780917	0.907475963607963	C12orf57	1
GO:0030049	muscle filament sliding	1/2053	14/18722	0.803418719780917	0.907475963607963	MYL6	1
GO:0031115	negative regulation of microtubule polymerization	1/2053	14/18722	0.803418719780917	0.907475963607963	STMN1	1
GO:0031468	nuclear membrane reassembly	1/2053	14/18722	0.803418719780917	0.907475963607963	UBXN2A	1
GO:0035630	bone mineralization involved in bone maturation	1/2053	14/18722	0.803418719780917	0.907475963607963	SNX10	1
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	1/2053	14/18722	0.803418719780917	0.907475963607963	PDGFA	1
GO:0035810	positive regulation of urine volume	1/2053	14/18722	0.803418719780917	0.907475963607963	GNAI2	1
GO:0035815	positive regulation of renal sodium excretion	1/2053	14/18722	0.803418719780917	0.907475963607963	GNAI2	1
GO:0043144	sno(s)RNA processing	1/2053	14/18722	0.803418719780917	0.907475963607963	FBL	1
GO:0043455	regulation of secondary metabolic process	1/2053	14/18722	0.803418719780917	0.907475963607963	ZEB2	1
GO:0043650	dicarboxylic acid biosynthetic process	1/2053	14/18722	0.803418719780917	0.907475963607963	KYNU	1
GO:0043951	negative regulation of cAMP-mediated signaling	1/2053	14/18722	0.803418719780917	0.907475963607963	RGS2	1
GO:0044154	histone H3-K14 acetylation	1/2053	14/18722	0.803418719780917	0.907475963607963	GATA3	1
GO:0046348	amino sugar catabolic process	1/2053	14/18722	0.803418719780917	0.907475963607963	ALDH1A1	1
GO:0046462	monoacylglycerol metabolic process	1/2053	14/18722	0.803418719780917	0.907475963607963	MGLL	1
GO:0046479	glycosphingolipid catabolic process	1/2053	14/18722	0.803418719780917	0.907475963607963	HEXB	1
GO:0048021	regulation of melanin biosynthetic process	1/2053	14/18722	0.803418719780917	0.907475963607963	ZEB2	1
GO:0048148	behavioral response to cocaine	1/2053	14/18722	0.803418719780917	0.907475963607963	HOMER1	1
GO:0048368	lateral mesoderm development	1/2053	14/18722	0.803418719780917	0.907475963607963	YAP1	1
GO:0048681	negative regulation of axon regeneration	1/2053	14/18722	0.803418719780917	0.907475963607963	SPP1	1
GO:0050667	homocysteine metabolic process	1/2053	14/18722	0.803418719780917	0.907475963607963	COMT	1
GO:0050872	white fat cell differentiation	1/2053	14/18722	0.803418719780917	0.907475963607963	PPARG	1
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	1/2053	14/18722	0.803418719780917	0.907475963607963	CXCR4	1
GO:0051547	regulation of keratinocyte migration	1/2053	14/18722	0.803418719780917	0.907475963607963	HBEGF	1
GO:0051645	Golgi localization	1/2053	14/18722	0.803418719780917	0.907475963607963	ARHGAP21	1
GO:0060732	positive regulation of inositol phosphate biosynthetic process	1/2053	14/18722	0.803418719780917	0.907475963607963	PTAFR	1
GO:0070307	lens fiber cell development	1/2053	14/18722	0.803418719780917	0.907475963607963	VIM	1
GO:0072498	embryonic skeletal joint development	1/2053	14/18722	0.803418719780917	0.907475963607963	BMP7	1
GO:0090128	regulation of synapse maturation	1/2053	14/18722	0.803418719780917	0.907475963607963	CLSTN1	1
GO:0090281	negative regulation of calcium ion import	1/2053	14/18722	0.803418719780917	0.907475963607963	VDAC1	1
GO:0098734	macromolecule depalmitoylation	1/2053	14/18722	0.803418719780917	0.907475963607963	PPT1	1
GO:0099638	endosome to plasma membrane protein transport	1/2053	14/18722	0.803418719780917	0.907475963607963	NSG1	1
GO:1900037	regulation of cellular response to hypoxia	1/2053	14/18722	0.803418719780917	0.907475963607963	CHCHD2	1
GO:1900376	regulation of secondary metabolite biosynthetic process	1/2053	14/18722	0.803418719780917	0.907475963607963	ZEB2	1
GO:1901077	regulation of relaxation of muscle	1/2053	14/18722	0.803418719780917	0.907475963607963	CAMK2D	1
GO:1901678	iron coordination entity transport	1/2053	14/18722	0.803418719780917	0.907475963607963	PGRMC2	1
GO:1902187	negative regulation of viral release from host cell	1/2053	14/18722	0.803418719780917	0.907475963607963	TRIM28	1
GO:1904152	regulation of retrograde protein transport, ER to cytosol	1/2053	14/18722	0.803418719780917	0.907475963607963	SVIP	1
GO:1905208	negative regulation of cardiocyte differentiation	1/2053	14/18722	0.803418719780917	0.907475963607963	EGFR	1
GO:0001708	cell fate specification	8/2053	92/18722	0.803924819057501	0.907705855164661	ITGB1/NOTCH1/LMO4/NRP1/ISL1/ESRP1/GLI3/TBX3	8
GO:0035249	synaptic transmission, glutamatergic	8/2053	92/18722	0.803924819057501	0.907705855164661	MEF2C/EGFR/LRRK2/TNF/CCR2/GLUL/PTK2B/HOMER1	8
GO:0050770	regulation of axonogenesis	14/2053	154/18722	0.80787554657865	0.911994972619361	FN1/SKIL/SPP1/VEGFA/PLXNC1/SEMA4A/ARHGAP4/TRPV2/SEMA6A/NRP1/GOLGA4/TWF2/SEMA6D/EFNA1	14
GO:1905037	autophagosome organization	9/2053	103/18722	0.809393481660561	0.913536661016435	LRRK2/VMP1/RALB/UBXN2A/TCIRG1/ATG16L2/GABARAP/TMEM41B/WIPI2	9
GO:0000737	DNA catabolic process, endonucleolytic	2/2053	27/18722	0.812245458771816	0.913833255696774	DNASE1L1/APEX1	2
GO:0001958	endochondral ossification	2/2053	27/18722	0.812245458771816	0.913833255696774	MEF2C/FOXC1	2
GO:0003401	axis elongation	2/2053	27/18722	0.812245458771816	0.913833255696774	YAP1/TRIM28	2
GO:0006783	heme biosynthetic process	2/2053	27/18722	0.812245458771816	0.913833255696774	TSPO/ALAD	2
GO:0014850	response to muscle activity	2/2053	27/18722	0.812245458771816	0.913833255696774	METRNL/FIS1	2
GO:0015813	L-glutamate transmembrane transport	2/2053	27/18722	0.812245458771816	0.913833255696774	ITGB1/SLC1A3	2
GO:0032781	positive regulation of ATPase activity	2/2053	27/18722	0.812245458771816	0.913833255696774	DNAJC9/PFN1	2
GO:0034505	tooth mineralization	2/2053	27/18722	0.812245458771816	0.913833255696774	TFAP2A/TCIRG1	2
GO:0035235	ionotropic glutamate receptor signaling pathway	2/2053	27/18722	0.812245458771816	0.913833255696774	APP/PTK2B	2
GO:0035459	vesicle cargo loading	2/2053	27/18722	0.812245458771816	0.913833255696774	PICALM/SEC31A	2
GO:0036075	replacement ossification	2/2053	27/18722	0.812245458771816	0.913833255696774	MEF2C/FOXC1	2
GO:0042403	thyroid hormone metabolic process	2/2053	27/18722	0.812245458771816	0.913833255696774	CTSB/GATA3	2
GO:0046174	polyol catabolic process	2/2053	27/18722	0.812245458771816	0.913833255696774	IMPA2/GK	2
GO:1901018	positive regulation of potassium ion transmembrane transporter activity	2/2053	27/18722	0.812245458771816	0.913833255696774	TREM2/AKAP9	2
GO:1903421	regulation of synaptic vesicle recycling	2/2053	27/18722	0.812245458771816	0.913833255696774	LRRK2/AP2M1	2
GO:1903859	regulation of dendrite extension	2/2053	27/18722	0.812245458771816	0.913833255696774	CXCR4/ITSN2	2
GO:1904357	negative regulation of telomere maintenance via telomere lengthening	2/2053	27/18722	0.812245458771816	0.913833255696774	PARP1/HNRNPA1	2
GO:0010665	regulation of cardiac muscle cell apoptotic process	4/2053	50/18722	0.812973149037209	0.913966440738852	JAK2/CAMK2D/BNIP3/MDK	4
GO:0090102	cochlea development	4/2053	50/18722	0.812973149037209	0.913966440738852	KCNQ1/MCM2/CCNA2/GATA3	4
GO:1902930	regulation of alcohol biosynthetic process	4/2053	50/18722	0.812973149037209	0.913966440738852	PLEK/PTAFR/SOD1/PTK2B	4
GO:1904738	vascular associated smooth muscle cell migration	4/2053	50/18722	0.812973149037209	0.913966440738852	MEF2C/DOCK4/ADAMTS1/RHOA	4
GO:0017158	regulation of calcium ion-dependent exocytosis	3/2053	39/18722	0.816512293604651	0.917086065448878	NOTCH1/GNAI2/SYT7	3
GO:0043267	negative regulation of potassium ion transport	3/2053	39/18722	0.816512293604651	0.917086065448878	PTK2B/KCNE3/ANK3	3
GO:0046461	neutral lipid catabolic process	3/2053	39/18722	0.816512293604651	0.917086065448878	SORL1/ABHD2/MGLL	3
GO:0046464	acylglycerol catabolic process	3/2053	39/18722	0.816512293604651	0.917086065448878	SORL1/ABHD2/MGLL	3
GO:1901861	regulation of muscle tissue development	3/2053	39/18722	0.816512293604651	0.917086065448878	TGFB1/MEF2C/CENPF	3
GO:0048193	Golgi vesicle transport	28/2053	296/18722	0.823054656714365	0.918245984419749	LAPTM5/SORL1/VAMP5/LRRK2/LMAN1/KRT18/TMED4/CSK/TMED9/ERGIC2/TAPBP/ERGIC3/GOLGA4/ANK3/PLPP3/SPTBN1/TMED3/GOPC/VPS13C/COMMD1/VCP/MYO5A/PITPNB/TFG/ARL1/KDELR2/SEC31A/STX6	28
GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	13/2053	146/18722	0.823807107775181	0.918245984419749	GPR65/GNAS/ADGRG1/PTGER4/ADGRE5/ADGRE2/CXCL10/S1PR4/LGR5/GNAI2/ADRB1/LGR4/ADGRG6	13
GO:0048488	synaptic vesicle endocytosis	5/2053	62/18722	0.824214947609679	0.918245984419749	ACTB/LRRK2/ITSN2/PICALM/AP2M1	5
GO:0048663	neuron fate commitment	5/2053	62/18722	0.824214947609679	0.918245984419749	NOTCH1/ISL1/ESRP1/GLI3/ID2	5
GO:0140238	presynaptic endocytosis	5/2053	62/18722	0.824214947609679	0.918245984419749	ACTB/LRRK2/ITSN2/PICALM/AP2M1	5
GO:0006098	pentose-phosphate shunt	1/2053	15/18722	0.824991382186827	0.918245984419749	RPIA	1
GO:0006570	tyrosine metabolic process	1/2053	15/18722	0.824991382186827	0.918245984419749	IL4I1	1
GO:0006825	copper ion transport	1/2053	15/18722	0.824991382186827	0.918245984419749	COX17	1
GO:0009083	branched-chain amino acid catabolic process	1/2053	15/18722	0.824991382186827	0.918245984419749	ECHS1	1
GO:0010752	regulation of cGMP-mediated signaling	1/2053	15/18722	0.824991382186827	0.918245984419749	PTK2B	1
GO:0010820	positive regulation of T cell chemotaxis	1/2053	15/18722	0.824991382186827	0.918245984419749	CCR2	1
GO:0014733	regulation of skeletal muscle adaptation	1/2053	15/18722	0.824991382186827	0.918245984419749	CAMK2G	1
GO:0014744	positive regulation of muscle adaptation	1/2053	15/18722	0.824991382186827	0.918245984419749	AIF1	1
GO:0016114	terpenoid biosynthetic process	1/2053	15/18722	0.824991382186827	0.918245984419749	FDPS	1
GO:0030252	growth hormone secretion	1/2053	15/18722	0.824991382186827	0.918245984419749	SERP1	1
GO:0032239	regulation of nucleobase-containing compound transport	1/2053	15/18722	0.824991382186827	0.918245984419749	TPR	1
GO:0033275	actin-myosin filament sliding	1/2053	15/18722	0.824991382186827	0.918245984419749	MYL6	1
GO:0034384	high-density lipoprotein particle clearance	1/2053	15/18722	0.824991382186827	0.918245984419749	TREM2	1
GO:0035627	ceramide transport	1/2053	15/18722	0.824991382186827	0.918245984419749	PSAP	1
GO:0036124	histone H3-K9 trimethylation	1/2053	15/18722	0.824991382186827	0.918245984419749	LMNA	1
GO:0043508	negative regulation of JUN kinase activity	1/2053	15/18722	0.824991382186827	0.918245984419749	GSTP1	1
GO:0043584	nose development	1/2053	15/18722	0.824991382186827	0.918245984419749	GLI3	1
GO:0043981	histone H4-K5 acetylation	1/2053	15/18722	0.824991382186827	0.918245984419749	PHF20	1
GO:0043982	histone H4-K8 acetylation	1/2053	15/18722	0.824991382186827	0.918245984419749	PHF20	1
GO:0045475	locomotor rhythm	1/2053	15/18722	0.824991382186827	0.918245984419749	ID2	1
GO:0045725	positive regulation of glycogen biosynthetic process	1/2053	15/18722	0.824991382186827	0.918245984419749	INSR	1
GO:0045836	positive regulation of meiotic nuclear division	1/2053	15/18722	0.824991382186827	0.918245984419749	RAD51AP1	1
GO:0046459	short-chain fatty acid metabolic process	1/2053	15/18722	0.824991382186827	0.918245984419749	ACSS1	1
GO:0046500	S-adenosylmethionine metabolic process	1/2053	15/18722	0.824991382186827	0.918245984419749	ENOPH1	1
GO:0048712	negative regulation of astrocyte differentiation	1/2053	15/18722	0.824991382186827	0.918245984419749	TREM2	1
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	1/2053	15/18722	0.824991382186827	0.918245984419749	KCNQ1	1
GO:0051284	positive regulation of sequestering of calcium ion	1/2053	15/18722	0.824991382186827	0.918245984419749	CALM2	1
GO:0051791	medium-chain fatty acid metabolic process	1/2053	15/18722	0.824991382186827	0.918245984419749	ABHD2	1
GO:0060026	convergent extension	1/2053	15/18722	0.824991382186827	0.918245984419749	TRIM28	1
GO:0060049	regulation of protein glycosylation	1/2053	15/18722	0.824991382186827	0.918245984419749	CHP1	1
GO:0071025	RNA surveillance	1/2053	15/18722	0.824991382186827	0.918245984419749	EXOSC8	1
GO:0071380	cellular response to prostaglandin E stimulus	1/2053	15/18722	0.824991382186827	0.918245984419749	PTGER4	1
GO:0072224	metanephric glomerulus development	1/2053	15/18722	0.824991382186827	0.918245984419749	LGR4	1
GO:0080154	regulation of fertilization	1/2053	15/18722	0.824991382186827	0.918245984419749	LHFPL2	1
GO:0090110	COPII-coated vesicle cargo loading	1/2053	15/18722	0.824991382186827	0.918245984419749	SEC31A	1
GO:0110156	methylguanosine-cap decapping	1/2053	15/18722	0.824991382186827	0.918245984419749	ZFP36	1
GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	1/2053	15/18722	0.824991382186827	0.918245984419749	CAMK2D	1
GO:1902902	negative regulation of autophagosome assembly	1/2053	15/18722	0.824991382186827	0.918245984419749	LRRK2	1
GO:1903543	positive regulation of exosomal secretion	1/2053	15/18722	0.824991382186827	0.918245984419749	SDCBP	1
GO:2000052	positive regulation of non-canonical Wnt signaling pathway	1/2053	15/18722	0.824991382186827	0.918245984419749	GPC3	1
GO:2000402	negative regulation of lymphocyte migration	1/2053	15/18722	0.824991382186827	0.918245984419749	IL27RA	1
GO:2000650	negative regulation of sodium ion transmembrane transporter activity	1/2053	15/18722	0.824991382186827	0.918245984419749	CAMK2D	1
GO:0009948	anterior/posterior axis specification	4/2053	51/18722	0.825044017001144	0.918245984419749	WLS/BASP1/TBX3/GPC3	4
GO:0045104	intermediate filament cytoskeleton organization	4/2053	51/18722	0.825044017001144	0.918245984419749	VIM/DSP/KRT18/SOD1	4
GO:0061035	regulation of cartilage development	6/2053	73/18722	0.825503938066806	0.91858746817523	EFEMP1/RARA/TRPS1/SCIN/GLI3/MDK	6
GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	2/2053	28/18722	0.828094990119455	0.919935186209356	SDF2L1/VCP	2
GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	2/2053	28/18722	0.828094990119455	0.919935186209356	PARD3/DGKD	2
GO:0007271	synaptic transmission, cholinergic	2/2053	28/18722	0.828094990119455	0.919935186209356	CHRNB1/CHRNA5	2
GO:0008299	isoprenoid biosynthetic process	2/2053	28/18722	0.828094990119455	0.919935186209356	FDPS/PMVK	2
GO:0009312	oligosaccharide biosynthetic process	2/2053	28/18722	0.828094990119455	0.919935186209356	FBP1/FUT8	2
GO:0031440	regulation of mRNA 3'-end processing	2/2053	28/18722	0.828094990119455	0.919935186209356	ZFP36L1/BARD1	2
GO:0045686	negative regulation of glial cell differentiation	2/2053	28/18722	0.828094990119455	0.919935186209356	NOTCH1/TREM2	2
GO:0070076	histone lysine demethylation	2/2053	28/18722	0.828094990119455	0.919935186209356	KDM1B/KDM6B	2
GO:1903020	positive regulation of glycoprotein metabolic process	2/2053	28/18722	0.828094990119455	0.919935186209356	PAWR/CHP1	2
GO:0032892	positive regulation of organic acid transport	3/2053	40/18722	0.829806288660509	0.921324524789611	IL1B/ITGB1/PTGES	3
GO:0072210	metanephric nephron development	3/2053	40/18722	0.829806288660509	0.921324524789611	STAT1/LGR4/IRX2	3
GO:1901020	negative regulation of calcium ion transmembrane transporter activity	3/2053	40/18722	0.829806288660509	0.921324524789611	CALM2/C4orf3/YWHAE	3
GO:0006836	neurotransmitter transport	19/2053	208/18722	0.831538409628334	0.923076865452359	MEF2C/LRRK2/STXBP2/SLC38A1/STX11/ITGB1/MCTP1/NR4A1/PNKD/SLC29A1/PRKCB/PPT1/SLC6A6/SLC6A4/SYT7/RAP1A/PARK7/CHRNA5/SLC1A3	19
GO:0030239	myofibril assembly	5/2053	63/18722	0.834713785164711	0.926259055111571	CSRP2/MEF2A/ITGB1/KRT8/OBSL1	5
GO:0045143	homologous chromosome segregation	5/2053	63/18722	0.834713785164711	0.926259055111571	CCNE1/RAD21/CCNE2/FANCD2/PSMC3IP	5
GO:0099565	chemical synaptic transmission, postsynaptic	9/2053	106/18722	0.834871654787664	0.926262930607616	MEF2C/LRRK2/APP/ARRB2/PTK2B/P2RX7/SLC29A1/CHRNB1/CHRNA5	9
GO:0034204	lipid translocation	4/2053	52/18722	0.836461835556795	0.927512661863014	P2RX7/PLSCR1/TMEM30B/KCNN4	4
GO:0045103	intermediate filament-based process	4/2053	52/18722	0.836461835556795	0.927512661863014	VIM/DSP/KRT18/SOD1	4
GO:0060071	Wnt signaling pathway, planar cell polarity pathway	4/2053	52/18722	0.836461835556795	0.927512661863014	RHOA/ZNRF3/DAAM1/GPC3	4
GO:0042472	inner ear morphogenesis	8/2053	96/18722	0.839636983249859	0.93020562006138	MAFB/SOD1/KCNQ1/TFAP2A/GATA3/ATP6V1B1/TRIOBP/MYO7A	8
GO:0042632	cholesterol homeostasis	8/2053	96/18722	0.839636983249859	0.93020562006138	NPC2/CD24/TMEM97/LRP5/LIMA1/IL18/MYLIP/LDLRAP1	8
GO:0048634	regulation of muscle organ development	3/2053	41/18722	0.842264423187356	0.93020562006138	TGFB1/MEF2C/CENPF	3
GO:0019082	viral protein processing	2/2053	29/18722	0.842728215686236	0.93020562006138	PARP9/FUT8	2
GO:0019433	triglyceride catabolic process	2/2053	29/18722	0.842728215686236	0.93020562006138	SORL1/MGLL	2
GO:0040018	positive regulation of multicellular organism growth	2/2053	29/18722	0.842728215686236	0.93020562006138	PPIB/EZR	2
GO:0042759	long-chain fatty acid biosynthetic process	2/2053	29/18722	0.842728215686236	0.93020562006138	ALOX5/GSTP1	2
GO:0090114	COPII-coated vesicle budding	2/2053	29/18722	0.842728215686236	0.93020562006138	TFG/SEC31A	2
GO:1901017	negative regulation of potassium ion transmembrane transporter activity	2/2053	29/18722	0.842728215686236	0.93020562006138	KCNE3/ANK3	2
GO:0001574	ganglioside biosynthetic process	1/2053	16/18722	0.84419770561498	0.93020562006138	ST3GAL5	1
GO:0006740	NADPH regeneration	1/2053	16/18722	0.84419770561498	0.93020562006138	RPIA	1
GO:0006750	glutathione biosynthetic process	1/2053	16/18722	0.84419770561498	0.93020562006138	GCLM	1
GO:0016074	sno(s)RNA metabolic process	1/2053	16/18722	0.84419770561498	0.93020562006138	FBL	1
GO:0016584	nucleosome positioning	1/2053	16/18722	0.84419770561498	0.93020562006138	SMARCA5	1
GO:0031268	pseudopodium organization	1/2053	16/18722	0.84419770561498	0.93020562006138	RAB25	1
GO:0034374	low-density lipoprotein particle remodeling	1/2053	16/18722	0.84419770561498	0.93020562006138	PLA2G7	1
GO:0034375	high-density lipoprotein particle remodeling	1/2053	16/18722	0.84419770561498	0.93020562006138	APOC1	1
GO:0035864	response to potassium ion	1/2053	16/18722	0.84419770561498	0.93020562006138	SOD1	1
GO:0042481	regulation of odontogenesis	1/2053	16/18722	0.84419770561498	0.93020562006138	SP6	1
GO:0042795	snRNA transcription by RNA polymerase II	1/2053	16/18722	0.84419770561498	0.93020562006138	ELL2	1
GO:0044804	autophagy of nucleus	1/2053	16/18722	0.84419770561498	0.93020562006138	WIPI2	1
GO:0045721	negative regulation of gluconeogenesis	1/2053	16/18722	0.84419770561498	0.93020562006138	PGP	1
GO:0045722	positive regulation of gluconeogenesis	1/2053	16/18722	0.84419770561498	0.93020562006138	DDB1	1
GO:0051969	regulation of transmission of nerve impulse	1/2053	16/18722	0.84419770561498	0.93020562006138	TYMP	1
GO:0060004	reflex	1/2053	16/18722	0.84419770561498	0.93020562006138	AFG3L2	1
GO:0060572	morphogenesis of an epithelial bud	1/2053	16/18722	0.84419770561498	0.93020562006138	BMP7	1
GO:0070571	negative regulation of neuron projection regeneration	1/2053	16/18722	0.84419770561498	0.93020562006138	SPP1	1
GO:0072283	metanephric renal vesicle morphogenesis	1/2053	16/18722	0.84419770561498	0.93020562006138	STAT1	1
GO:0099116	tRNA 5'-end processing	1/2053	16/18722	0.84419770561498	0.93020562006138	POP7	1
GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	1/2053	16/18722	0.84419770561498	0.93020562006138	ATP2B1	1
GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway	1/2053	16/18722	0.84419770561498	0.93020562006138	SEMA6A	1
GO:1904862	inhibitory synapse assembly	1/2053	16/18722	0.84419770561498	0.93020562006138	SEMA4A	1
GO:1904948	midbrain dopaminergic neuron differentiation	1/2053	16/18722	0.84419770561498	0.93020562006138	NR4A2	1
GO:2000846	regulation of corticosteroid hormone secretion	1/2053	16/18722	0.84419770561498	0.93020562006138	C1QTNF1	1
GO:0008088	axo-dendritic transport	6/2053	75/18722	0.844471668745723	0.93020562006138	APP/SOD1/HSPA8/ARMCX3/KIF4A/PURA	6
GO:0036465	synaptic vesicle recycling	6/2053	75/18722	0.844471668745723	0.93020562006138	ACTB/LRRK2/ITSN2/SYT7/PICALM/AP2M1	6
GO:0055002	striated muscle cell development	5/2053	64/18722	0.844693937433193	0.930279666776644	CSRP2/MEF2A/ITGB1/KRT8/OBSL1	5
GO:0006493	protein O-linked glycosylation	7/2053	86/18722	0.845653692156426	0.930824097035141	GALNT11/C1GALT1/TMTC3/GXYLT1/C1GALT1C1/GALNT18/DPM2	7
GO:0032413	negative regulation of ion transmembrane transporter activity	7/2053	86/18722	0.845653692156426	0.930824097035141	CAMK2D/KCNE3/CALM2/C4orf3/ANK3/GOPC/YWHAE	7
GO:0046928	regulation of neurotransmitter secretion	7/2053	86/18722	0.845653692156426	0.930824097035141	MEF2C/LRRK2/MCTP1/PNKD/PRKCB/RAP1A/CHRNA5	7
GO:0030216	keratinocyte differentiation	12/2053	139/18722	0.846855669908067	0.931976159106457	TXNIP/ZFP36/DSP/NOTCH1/ZFP36L1/VDR/CSTA/YAP1/PALLD/STK4/FOXC1/KRT10	12
GO:0099172	presynapse organization	4/2053	53/18722	0.84724889898399	0.932237922960561	C5AR1/APP/SDCBP/EIF4G1	4
GO:0006721	terpenoid metabolic process	8/2053	97/18722	0.847712922978714	0.932406514733691	EGFR/LRP2/FDPS/ADH5/AKR1B1/ALDH1A1/SCPEP1/FDFT1	8
GO:0055092	sterol homeostasis	8/2053	97/18722	0.847712922978714	0.932406514733691	NPC2/CD24/TMEM97/LRP5/LIMA1/IL18/MYLIP/LDLRAP1	8
GO:0046474	glycerophospholipid biosynthetic process	19/2053	211/18722	0.848619793655729	0.933232910911725	LPCAT2/SOCS3/AGPAT2/CHPT1/GPAA1/PGAP2/FABP5/SH3YL1/PLSCR1/IMPA2/DGKD/INPP5D/CDS1/SLC44A1/PISD/CDIPT/SLC44A2/PDGFA/DPM2	19
GO:0009952	anterior/posterior pattern specification	18/2053	201/18722	0.849407751875943	0.933928259346831	WLS/PRKDC/NOTCH1/HHEX/NR2F2/LFNG/BTG2/PBX1/LRP5/BHLHE40/GLI3/FOXC1/BHLHE41/BASP1/TBX3/COBL/GPC3/XRCC2	18
GO:0022037	metencephalon development	9/2053	108/18722	0.850330383639587	0.934771400116805	AIF1/HSPA5/EZH2/UQCRQ/HNRNPD/RERE/FOXC1/MDK/PTN	9
GO:0006040	amino sugar metabolic process	3/2053	42/18722	0.853924207292632	0.937348196808597	EXTL2/ALDH1A1/GFPT1	3
GO:0019432	triglyceride biosynthetic process	3/2053	42/18722	0.853924207292632	0.937348196808597	C3/ACSL4/GK	3
GO:0042168	heme metabolic process	3/2053	42/18722	0.853924207292632	0.937348196808597	TSPO/HMOX1/ALAD	3
GO:0045214	sarcomere organization	3/2053	42/18722	0.853924207292632	0.937348196808597	CSRP2/ITGB1/KRT8	3
GO:0045292	mRNA cis splicing, via spliceosome	3/2053	42/18722	0.853924207292632	0.937348196808597	PSIP1/RBM17/WBP11	3
GO:0060999	positive regulation of dendritic spine development	3/2053	42/18722	0.853924207292632	0.937348196808597	CAMK1/ACTR2/DLG5	3
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	3/2053	42/18722	0.853924207292632	0.937348196808597	KLF4/NOTCH1/RHOA	3
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	3/2053	42/18722	0.853924207292632	0.937348196808597	ISG20/EXOSC8/TOE1	3
GO:0003299	muscle hypertrophy in response to stress	2/2053	30/18722	0.856221154327493	0.937810683819817	EZH2/LMNA	2
GO:0010453	regulation of cell fate commitment	2/2053	30/18722	0.856221154327493	0.937810683819817	LMO4/ESRP1	2
GO:0014887	cardiac muscle adaptation	2/2053	30/18722	0.856221154327493	0.937810683819817	EZH2/LMNA	2
GO:0014898	cardiac muscle hypertrophy in response to stress	2/2053	30/18722	0.856221154327493	0.937810683819817	EZH2/LMNA	2
GO:0015721	bile acid and bile salt transport	2/2053	30/18722	0.856221154327493	0.937810683819817	AQP9/SLC10A3	2
GO:0034368	protein-lipid complex remodeling	2/2053	30/18722	0.856221154327493	0.937810683819817	PLA2G7/APOC1	2
GO:0034369	plasma lipoprotein particle remodeling	2/2053	30/18722	0.856221154327493	0.937810683819817	PLA2G7/APOC1	2
GO:0034694	response to prostaglandin	2/2053	30/18722	0.856221154327493	0.937810683819817	PTGER4/TGFBR3	2
GO:0036258	multivesicular body assembly	2/2053	30/18722	0.856221154327493	0.937810683819817	CHMP4C/VPS25	2
GO:0048240	sperm capacitation	2/2053	30/18722	0.856221154327493	0.937810683819817	ABHD2/DEFB1	2
GO:0060351	cartilage development involved in endochondral bone morphogenesis	2/2053	30/18722	0.856221154327493	0.937810683819817	RARA/SERPINH1	2
GO:0099068	postsynapse assembly	2/2053	30/18722	0.856221154327493	0.937810683819817	ABI3/ZDHHC12	2
GO:0015918	sterol transport	11/2053	130/18722	0.856499501064594	0.937944334073291	TSPO/MSR1/NPC2/CD36/NFKBIA/TREM2/APOC1/SYT7/LIMA1/LDLRAP1/PPARG	11
GO:0007215	glutamate receptor signaling pathway	4/2053	54/18722	0.857428225879355	0.938061874952536	HOMER3/APP/PTK2B/HOMER1	4
GO:0010659	cardiac muscle cell apoptotic process	4/2053	54/18722	0.857428225879355	0.938061874952536	JAK2/CAMK2D/BNIP3/MDK	4
GO:0060350	endochondral bone morphogenesis	4/2053	54/18722	0.857428225879355	0.938061874952536	MEF2C/RARA/SERPINH1/FOXC1	4
GO:2000300	regulation of synaptic vesicle exocytosis	4/2053	54/18722	0.857428225879355	0.938061874952536	LRRK2/PRKCB/RAP1A/CHRNA5	4
GO:0001710	mesodermal cell fate commitment	1/2053	17/18722	0.861297144852254	0.938061874952536	KLF4	1
GO:0002031	G protein-coupled receptor internalization	1/2053	17/18722	0.861297144852254	0.938061874952536	ARRB2	1
GO:0006474	N-terminal protein amino acid acetylation	1/2053	17/18722	0.861297144852254	0.938061874952536	SOX4	1
GO:0006577	amino-acid betaine metabolic process	1/2053	17/18722	0.861297144852254	0.938061874952536	ALDH7A1	1
GO:0006744	ubiquinone biosynthetic process	1/2053	17/18722	0.861297144852254	0.938061874952536	COQ4	1
GO:0006895	Golgi to endosome transport	1/2053	17/18722	0.861297144852254	0.938061874952536	VPS13C	1
GO:0007625	grooming behavior	1/2053	17/18722	0.861297144852254	0.938061874952536	PPT1	1
GO:0008334	histone mRNA metabolic process	1/2053	17/18722	0.861297144852254	0.938061874952536	SLBP	1
GO:0009812	flavonoid metabolic process	1/2053	17/18722	0.861297144852254	0.938061874952536	SULT1A1	1
GO:0010470	regulation of gastrulation	1/2053	17/18722	0.861297144852254	0.938061874952536	DAG1	1
GO:0010612	regulation of cardiac muscle adaptation	1/2053	17/18722	0.861297144852254	0.938061874952536	LMNA	1
GO:0010831	positive regulation of myotube differentiation	1/2053	17/18722	0.861297144852254	0.938061874952536	MAPK14	1
GO:0021513	spinal cord dorsal/ventral patterning	1/2053	17/18722	0.861297144852254	0.938061874952536	GLI3	1
GO:0034349	glial cell apoptotic process	1/2053	17/18722	0.861297144852254	0.938061874952536	TREM2	1
GO:0035518	histone H2A monoubiquitination	1/2053	17/18722	0.861297144852254	0.938061874952536	DDB1	1
GO:0046855	inositol phosphate dephosphorylation	1/2053	17/18722	0.861297144852254	0.938061874952536	IMPA2	1
GO:0048521	negative regulation of behavior	1/2053	17/18722	0.861297144852254	0.938061874952536	RETN	1
GO:0048791	calcium ion-regulated exocytosis of neurotransmitter	1/2053	17/18722	0.861297144852254	0.938061874952536	SYT7	1
GO:0051580	regulation of neurotransmitter uptake	1/2053	17/18722	0.861297144852254	0.938061874952536	ITGB1	1
GO:0061577	calcium ion transmembrane transport via high voltage-gated calcium channel	1/2053	17/18722	0.861297144852254	0.938061874952536	CAMK2D	1
GO:0061952	midbody abscission	1/2053	17/18722	0.861297144852254	0.938061874952536	CHMP4C	1
GO:0090494	dopamine uptake	1/2053	17/18722	0.861297144852254	0.938061874952536	PARK7	1
GO:1901663	quinone biosynthetic process	1/2053	17/18722	0.861297144852254	0.938061874952536	COQ4	1
GO:1903242	regulation of cardiac muscle hypertrophy in response to stress	1/2053	17/18722	0.861297144852254	0.938061874952536	LMNA	1
GO:1903541	regulation of exosomal secretion	1/2053	17/18722	0.861297144852254	0.938061874952536	SDCBP	1
GO:1903818	positive regulation of voltage-gated potassium channel activity	1/2053	17/18722	0.861297144852254	0.938061874952536	TREM2	1
GO:0021510	spinal cord development	8/2053	99/18722	0.86288944505693	0.939625530007546	NOTCH1/LMO4/ISL1/SUZ12/SOX4/GLI3/PTN/ACTL6A	8
GO:1902476	chloride transmembrane transport	5/2053	66/18722	0.863160843623373	0.939750510205087	SLC26A2/GABRE/BEST1/PCYOX1/SLC1A3	5
GO:0032365	intracellular lipid transport	3/2053	43/18722	0.864823421433653	0.941048336706913	NPC2/SYT7/LDLRAP1	3
GO:0034661	ncRNA catabolic process	3/2053	43/18722	0.864823421433653	0.941048336706913	LIN28B/EXOSC8/SND1	3
GO:0098815	modulation of excitatory postsynaptic potential	3/2053	43/18722	0.864823421433653	0.941048336706913	LRRK2/APP/PTK2B	3
GO:0048562	embryonic organ morphogenesis	26/2053	285/18722	0.865484561547104	0.941596984457412	MAFB/MEF2C/EFEMP1/FBN2/FBN1/SOD1/BMP7/ENG/NOTCH1/KCNQ1/SLC39A1/MFAP5/TFAP2A/NOTCH2/AHI1/GATA3/FOLR1/EFNA1/YAP1/ATP6V1B1/DLG1/GLI3/ID2/TRIOBP/TBX3/MYO7A	26
GO:0002455	humoral immune response mediated by circulating immunoglobulin	10/2053	121/18722	0.866789794722985	0.942304595952049	PTPRC/TNF/C3/CD46/PTPN6/TREM2/C1QA/C1QBP/EXO1/SERPING1	10
GO:0006414	translational elongation	4/2053	55/18722	0.867023331080245	0.942304595952049	RPLP1/RPLP2/TSFM/ASCC3	4
GO:0046164	alcohol catabolic process	4/2053	55/18722	0.867023331080245	0.942304595952049	ALDH2/SULT1A1/IMPA2/GK	4
GO:0002063	chondrocyte development	2/2053	31/18722	0.868647786701798	0.942304595952049	SERPINH1/SULF2	2
GO:0002323	natural killer cell activation involved in immune response	2/2053	31/18722	0.868647786701798	0.942304595952049	CORO1A/HLA-F	2
GO:0006613	cotranslational protein targeting to membrane	2/2053	31/18722	0.868647786701798	0.942304595952049	SEC63/SIL1	2
GO:0006779	porphyrin-containing compound biosynthetic process	2/2053	31/18722	0.868647786701798	0.942304595952049	TSPO/ALAD	2
GO:0016577	histone demethylation	2/2053	31/18722	0.868647786701798	0.942304595952049	KDM1B/KDM6B	2
GO:0033014	tetrapyrrole biosynthetic process	2/2053	31/18722	0.868647786701798	0.942304595952049	TSPO/ALAD	2
GO:0034472	snRNA 3'-end processing	2/2053	31/18722	0.868647786701798	0.942304595952049	EXOSC8/TOE1	2
GO:0035115	embryonic forelimb morphogenesis	2/2053	31/18722	0.868647786701798	0.942304595952049	TFAP2A/TBX3	2
GO:0036257	multivesicular body organization	2/2053	31/18722	0.868647786701798	0.942304595952049	CHMP4C/VPS25	2
GO:0055022	negative regulation of cardiac muscle tissue growth	2/2053	31/18722	0.868647786701798	0.942304595952049	GJA1/RGS2	2
GO:0060795	cell fate commitment involved in formation of primary germ layer	2/2053	31/18722	0.868647786701798	0.942304595952049	KLF4/RTF1	2
GO:0061117	negative regulation of heart growth	2/2053	31/18722	0.868647786701798	0.942304595952049	GJA1/RGS2	2
GO:2000144	positive regulation of DNA-templated transcription, initiation	2/2053	31/18722	0.868647786701798	0.942304595952049	JUN/ERCC1	2
GO:0032371	regulation of sterol transport	6/2053	78/18722	0.869744633824278	0.943051387167737	TSPO/NFKBIA/TREM2/APOC1/LDLRAP1/PPARG	6
GO:0032374	regulation of cholesterol transport	6/2053	78/18722	0.869744633824278	0.943051387167737	TSPO/NFKBIA/TREM2/APOC1/LDLRAP1/PPARG	6
GO:0006641	triglyceride metabolic process	8/2053	100/18722	0.870005027419808	0.943051387167737	SORL1/GPX1/C3/APOBR/APOC1/ACSL4/MGLL/GK	8
GO:0051588	regulation of neurotransmitter transport	8/2053	100/18722	0.870005027419808	0.943051387167737	MEF2C/LRRK2/ITGB1/MCTP1/PNKD/PRKCB/RAP1A/CHRNA5	8
GO:0009100	glycoprotein metabolic process	36/2053	387/18722	0.874479072603538	0.943051387167737	CST3/CTSL/RPN2/DDOST/TUSC3/SERP1/ST3GAL5/GALNT11/HPSE/EXTL2/CHPF/HBEGF/ASGR2/PAWR/ITM2C/CHP1/SULF2/CHST15/FBXO6/CHST14/FUT8/C1GALT1/DSE/GANAB/TMTC3/PARK7/GXYLT1/GPC1/AGO2/C1GALT1C1/B3GAT3/GALNT18/GFPT1/DPM2/HS6ST2/ALG8	36
GO:0005978	glycogen biosynthetic process	3/2053	44/18722	0.874999777526637	0.943051387167737	AGL/UGP2/INSR	3
GO:0006378	mRNA polyadenylation	3/2053	44/18722	0.874999777526637	0.943051387167737	APP/PABPC1/WDR33	3
GO:0006775	fat-soluble vitamin metabolic process	3/2053	44/18722	0.874999777526637	0.943051387167737	LRP2/TNF/VKORC1	3
GO:0008542	visual learning	3/2053	44/18722	0.874999777526637	0.943051387167737	APP/ITGB1/MEIS2	3
GO:0009250	glucan biosynthetic process	3/2053	44/18722	0.874999777526637	0.943051387167737	AGL/UGP2/INSR	3
GO:0090175	regulation of establishment of planar polarity	4/2053	56/18722	0.87605802229032	0.943051387167737	RHOA/ZNRF3/DAAM1/GPC3	4
GO:0001522	pseudouridine synthesis	1/2053	18/18722	0.876520719384107	0.943051387167737	NHP2	1
GO:0003417	growth plate cartilage development	1/2053	18/18722	0.876520719384107	0.943051387167737	RARA	1
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	1/2053	18/18722	0.876520719384107	0.943051387167737	ALG8	1
GO:0006991	response to sterol depletion	1/2053	18/18722	0.876520719384107	0.943051387167737	LYN	1
GO:0007250	activation of NF-kappaB-inducing kinase activity	1/2053	18/18722	0.876520719384107	0.943051387167737	TLR6	1
GO:0009404	toxin metabolic process	1/2053	18/18722	0.876520719384107	0.943051387167737	ARL1	1
GO:0015936	coenzyme A metabolic process	1/2053	18/18722	0.876520719384107	0.943051387167737	NUDT8	1
GO:0019184	nonribosomal peptide biosynthetic process	1/2053	18/18722	0.876520719384107	0.943051387167737	GCLM	1
GO:0019896	axonal transport of mitochondrion	1/2053	18/18722	0.876520719384107	0.943051387167737	ARMCX3	1
GO:0021511	spinal cord patterning	1/2053	18/18722	0.876520719384107	0.943051387167737	GLI3	1
GO:0032095	regulation of response to food	1/2053	18/18722	0.876520719384107	0.943051387167737	NENF	1
GO:0034433	steroid esterification	1/2053	18/18722	0.876520719384107	0.943051387167737	APOC1	1
GO:0034434	sterol esterification	1/2053	18/18722	0.876520719384107	0.943051387167737	APOC1	1
GO:0034435	cholesterol esterification	1/2053	18/18722	0.876520719384107	0.943051387167737	APOC1	1
GO:0035372	protein localization to microtubule	1/2053	18/18722	0.876520719384107	0.943051387167737	KIF20B	1
GO:0042136	neurotransmitter biosynthetic process	1/2053	18/18722	0.876520719384107	0.943051387167737	SLC6A4	1
GO:0045187	regulation of circadian sleep/wake cycle, sleep	1/2053	18/18722	0.876520719384107	0.943051387167737	ADRB1	1
GO:0045623	negative regulation of T-helper cell differentiation	1/2053	18/18722	0.876520719384107	0.943051387167737	BCL6	1
GO:0045653	negative regulation of megakaryocyte differentiation	1/2053	18/18722	0.876520719384107	0.943051387167737	CIB1	1
GO:0045956	positive regulation of calcium ion-dependent exocytosis	1/2053	18/18722	0.876520719384107	0.943051387167737	SYT7	1
GO:0046838	phosphorylated carbohydrate dephosphorylation	1/2053	18/18722	0.876520719384107	0.943051387167737	IMPA2	1
GO:0048535	lymph node development	1/2053	18/18722	0.876520719384107	0.943051387167737	TGFB1	1
GO:0048643	positive regulation of skeletal muscle tissue development	1/2053	18/18722	0.876520719384107	0.943051387167737	MEF2C	1
GO:0051895	negative regulation of focal adhesion assembly	1/2053	18/18722	0.876520719384107	0.943051387167737	CORO1C	1
GO:0060438	trachea development	1/2053	18/18722	0.876520719384107	0.943051387167737	RARA	1
GO:0060457	negative regulation of digestive system process	1/2053	18/18722	0.876520719384107	0.943051387167737	HAMP	1
GO:0060602	branch elongation of an epithelium	1/2053	18/18722	0.876520719384107	0.943051387167737	YAP1	1
GO:0071786	endoplasmic reticulum tubular network organization	1/2053	18/18722	0.876520719384107	0.943051387167737	TMEM170A	1
GO:0072189	ureter development	1/2053	18/18722	0.876520719384107	0.943051387167737	GATA3	1
GO:0110154	RNA decapping	1/2053	18/18722	0.876520719384107	0.943051387167737	ZFP36	1
GO:0150118	negative regulation of cell-substrate junction organization	1/2053	18/18722	0.876520719384107	0.943051387167737	CORO1C	1
GO:1901317	regulation of flagellated sperm motility	1/2053	18/18722	0.876520719384107	0.943051387167737	DEFB1	1
GO:1902548	negative regulation of cellular response to vascular endothelial growth factor stimulus	1/2053	18/18722	0.876520719384107	0.943051387167737	SEMA6A	1
GO:2001135	regulation of endocytic recycling	1/2053	18/18722	0.876520719384107	0.943051387167737	SORL1	1
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	7/2053	90/18722	0.876566264372412	0.943051387167737	LRRK2/PLK3/TRIB1/HSPA1A/VCP/PLK2/GABARAP	7
GO:1903509	liposaccharide metabolic process	8/2053	101/18722	0.876815968394319	0.943150916164559	AOAH/ST3GAL5/GPAA1/PGAP2/FUCA1/HEXB/DPM2/ITGB8	8
GO:0001895	retina homeostasis	6/2053	79/18722	0.877369617348427	0.943577290570095	LYZ/B2M/ACTB/SLC2A1/SOD1/PRDX1	6
GO:0010667	negative regulation of cardiac muscle cell apoptotic process	2/2053	32/18722	0.880079588181942	0.945387302942382	JAK2/MDK	2
GO:0019835	cytolysis	2/2053	32/18722	0.880079588181942	0.945387302942382	LYZ/TGFB1	2
GO:0019934	cGMP-mediated signaling	2/2053	32/18722	0.880079588181942	0.945387302942382	CD36/PTK2B	2
GO:0034367	protein-containing complex remodeling	2/2053	32/18722	0.880079588181942	0.945387302942382	PLA2G7/APOC1	2
GO:0061036	positive regulation of cartilage development	2/2053	32/18722	0.880079588181942	0.945387302942382	GLI3/MDK	2
GO:0061037	negative regulation of cartilage development	2/2053	32/18722	0.880079588181942	0.945387302942382	EFEMP1/RARA	2
GO:0006665	sphingolipid metabolic process	13/2053	155/18722	0.880155579039358	0.945387302942382	PSAP/HACD3/TECR/ST3GAL5/ORMDL1/PPT1/DEGS1/SPHK1/PLPP3/SERINC2/HEXB/HACD4/ITGB8	13
GO:0007269	neurotransmitter secretion	12/2053	145/18722	0.88316491501936	0.948280152132455	MEF2C/LRRK2/STXBP2/STX11/MCTP1/NR4A1/PNKD/PRKCB/PPT1/SYT7/RAP1A/CHRNA5	12
GO:0099643	signal release from synapse	12/2053	145/18722	0.88316491501936	0.948280152132455	MEF2C/LRRK2/STXBP2/STX11/MCTP1/NR4A1/PNKD/PRKCB/PPT1/SYT7/RAP1A/CHRNA5	12
GO:0034308	primary alcohol metabolic process	8/2053	102/18722	0.883330412688477	0.948288151034328	ALDH2/ACSS1/AKR7A2/ADH5/SULT1A1/AKR1B1/ALDH1A1/PARK7	8
GO:0006903	vesicle targeting	3/2053	45/18722	0.884490632264095	0.948684982764492	TMED9/CHP1/TFG	3
GO:0032309	icosanoid secretion	3/2053	45/18722	0.884490632264095	0.948684982764492	IL1B/SYK/PTGES	3
GO:0043631	RNA polyadenylation	3/2053	45/18722	0.884490632264095	0.948684982764492	APP/PABPC1/WDR33	3
GO:0044088	regulation of vacuole organization	3/2053	45/18722	0.884490632264095	0.948684982764492	LRRK2/GRN/RALB	3
GO:0048599	oocyte development	3/2053	45/18722	0.884490632264095	0.948684982764492	PTK2B/FBXO5/BRCA2	3
GO:0051648	vesicle localization	15/2053	177/18722	0.885424182406799	0.949516549497907	MYO1F/MYO1G/LRRK2/ITGA4/TMED9/CHP1/MYO1C/FNBP1L/TCIRG1/PICALM/MYO5A/TFG/CCDC186/ACTN4/MYO7A	15
GO:0048167	regulation of synaptic plasticity	17/2053	198/18722	0.886295851884955	0.9502814709274	TYROBP/LILRB2/MEF2C/APP/NSG1/MME/RARA/MCTP1/PTK2B/CX3CR1/HRAS/STAU1/SYT7/NRGN/EIF2AK4/PLK2/PTN	17
GO:0019226	transmission of nerve impulse	5/2053	69/18722	0.887374647621576	0.950295417336966	TYMP/SOD1/CNTNAP2/ANK3/JAM3	5
GO:0033344	cholesterol efflux	5/2053	69/18722	0.887374647621576	0.950295417336966	NPC2/NFKBIA/TREM2/APOC1/PPARG	5
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	14/2053	167/18722	0.887771220395798	0.950295417336966	PECAM1/CD84/CDH1/CADM1/BSG/TENM3/ITGB1/DSG2/DSC3/FAT1/DSC2/OBSL1/PALLD/CLSTN1	14
GO:0048839	inner ear development	16/2053	188/18722	0.88811511542009	0.950295417336966	MAFB/SOD1/NOTCH1/KCNQ1/LGR5/MCM2/TFAP2A/CCNA2/MCOLN3/AHI1/GATA3/ESRP1/ATP6V1B1/GLI3/TRIOBP/MYO7A	16
GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic	1/2053	19/18722	0.890074128446577	0.950295417336966	EXOSC8	1
GO:0006044	N-acetylglucosamine metabolic process	1/2053	19/18722	0.890074128446577	0.950295417336966	EXTL2	1
GO:0006490	oligosaccharide-lipid intermediate biosynthetic process	1/2053	19/18722	0.890074128446577	0.950295417336966	ALG8	1
GO:0006743	ubiquinone metabolic process	1/2053	19/18722	0.890074128446577	0.950295417336966	COQ4	1
GO:0009301	snRNA transcription	1/2053	19/18722	0.890074128446577	0.950295417336966	ELL2	1
GO:0042776	mitochondrial ATP synthesis coupled proton transport	1/2053	19/18722	0.890074128446577	0.950295417336966	STOML2	1
GO:0051957	positive regulation of amino acid transport	1/2053	19/18722	0.890074128446577	0.950295417336966	ITGB1	1
GO:0060065	uterus development	1/2053	19/18722	0.890074128446577	0.950295417336966	GATA3	1
GO:0071545	inositol phosphate catabolic process	1/2053	19/18722	0.890074128446577	0.950295417336966	IMPA2	1
GO:0072077	renal vesicle morphogenesis	1/2053	19/18722	0.890074128446577	0.950295417336966	STAT1	1
GO:1903204	negative regulation of oxidative stress-induced neuron death	1/2053	19/18722	0.890074128446577	0.950295417336966	PARK7	1
GO:2000319	regulation of T-helper 17 cell differentiation	1/2053	19/18722	0.890074128446577	0.950295417336966	NFKBIZ	1
GO:0001881	receptor recycling	2/2053	33/18722	0.890585188614294	0.950295417336966	SORL1/NSG1	2
GO:0006482	protein demethylation	2/2053	33/18722	0.890585188614294	0.950295417336966	KDM1B/KDM6B	2
GO:0006654	phosphatidic acid biosynthetic process	2/2053	33/18722	0.890585188614294	0.950295417336966	AGPAT2/DGKD	2
GO:0008214	protein dealkylation	2/2053	33/18722	0.890585188614294	0.950295417336966	KDM1B/KDM6B	2
GO:0018345	protein palmitoylation	2/2053	33/18722	0.890585188614294	0.950295417336966	GLUL/ZDHHC12	2
GO:0048730	epidermis morphogenesis	2/2053	33/18722	0.890585188614294	0.950295417336966	KLF4/NOTCH1	2
GO:0050974	detection of mechanical stimulus involved in sensory perception	2/2053	33/18722	0.890585188614294	0.950295417336966	CXCR4/KCNQ1	2
GO:0099174	regulation of presynapse organization	2/2053	33/18722	0.890585188614294	0.950295417336966	APP/EIF4G1	2
GO:1901380	negative regulation of potassium ion transmembrane transport	2/2053	33/18722	0.890585188614294	0.950295417336966	KCNE3/ANK3	2
GO:1902992	negative regulation of amyloid precursor protein catabolic process	2/2053	33/18722	0.890585188614294	0.950295417336966	SORL1/PICALM	2
GO:1905606	regulation of presynapse assembly	2/2053	33/18722	0.890585188614294	0.950295417336966	APP/EIF4G1	2
GO:0006984	ER-nucleus signaling pathway	3/2053	46/18722	0.893332747335843	0.952718891577508	CCDC47/HSPA5/PPP1R15A	3
GO:0010830	regulation of myotube differentiation	3/2053	46/18722	0.893332747335843	0.952718891577508	NOTCH1/BHLHE41/MAPK14	3
GO:0048701	embryonic cranial skeleton morphogenesis	3/2053	46/18722	0.893332747335843	0.952718891577508	SLC39A1/TFAP2A/GLI3	3
GO:0007626	locomotory behavior	15/2053	179/18722	0.894826397748054	0.954142240356908	LRRK2/NR4A2/APP/ARRB2/SOD1/DPP4/CSTB/PPT1/MCOLN3/EPS8/PARK7/PAK6/GAA/ID2/HEXB	15
GO:0045017	glycerolipid biosynthetic process	22/2053	252/18722	0.896518671112884	0.955776834875142	LPCAT2/C3/SOCS3/AGPAT2/CHPT1/GPAA1/PGAP2/FABP5/SH3YL1/ACSL4/PLSCR1/IMPA2/DGKD/INPP5D/CDS1/SLC44A1/PISD/CDIPT/GK/SLC44A2/PDGFA/DPM2	22
GO:0034754	cellular hormone metabolic process	11/2053	137/18722	0.897197137365266	0.956160359536696	TSPO/SPP1/IL4I1/HSD17B1/COMT/SULT1A1/AKR1B1/ALDH1A1/SCPEP1/HSD17B11/PLEKHA1	11
GO:0060078	regulation of postsynaptic membrane potential	11/2053	137/18722	0.897197137365266	0.956160359536696	MEF2C/LRRK2/APP/ARRB2/PTK2B/P2RX7/SLC29A1/ADRB1/GABRE/CHRNB1/CHRNA5	11
GO:0019369	arachidonic acid metabolic process	4/2053	59/18722	0.900038450837347	0.956332711989224	GPX1/ALOX5/TBXAS1/MGLL	4
GO:0046488	phosphatidylinositol metabolic process	13/2053	159/18722	0.900065403760545	0.956332711989224	PLEK/CSF1R/SOCS3/PLCB2/GPAA1/PGAP2/SH3YL1/IMPA2/INPP5D/CDS1/CDIPT/PDGFA/DPM2	13
GO:0007616	long-term memory	2/2053	34/18722	0.900230136745186	0.956332711989224	SGK1/EIF2AK4	2
GO:0048741	skeletal muscle fiber development	2/2053	34/18722	0.900230136745186	0.956332711989224	GPX1/HOMER1	2
GO:0016073	snRNA metabolic process	3/2053	47/18722	0.901562091557904	0.956332711989224	EXOSC8/NHP2/TOE1	3
GO:0032369	negative regulation of lipid transport	3/2053	47/18722	0.901562091557904	0.956332711989224	APOC1/ITGAV/FIS1	3
GO:0006896	Golgi to vacuole transport	1/2053	20/18722	0.902140524976501	0.956332711989224	LAPTM5	1
GO:0007097	nuclear migration	1/2053	20/18722	0.902140524976501	0.956332711989224	SYNE2	1
GO:0007620	copulation	1/2053	20/18722	0.902140524976501	0.956332711989224	SLC6A4	1
GO:0009110	vitamin biosynthetic process	1/2053	20/18722	0.902140524976501	0.956332711989224	TNF	1
GO:0010523	negative regulation of calcium ion transport into cytosol	1/2053	20/18722	0.902140524976501	0.956332711989224	CALM2	1
GO:0010893	positive regulation of steroid biosynthetic process	1/2053	20/18722	0.902140524976501	0.956332711989224	TNF	1
GO:0014047	glutamate secretion	1/2053	20/18722	0.902140524976501	0.956332711989224	GJA1	1
GO:0021516	dorsal spinal cord development	1/2053	20/18722	0.902140524976501	0.956332711989224	LMO4	1
GO:0032211	negative regulation of telomere maintenance via telomerase	1/2053	20/18722	0.902140524976501	0.956332711989224	HNRNPA1	1
GO:0032332	positive regulation of chondrocyte differentiation	1/2053	20/18722	0.902140524976501	0.956332711989224	GLI3	1
GO:0043046	DNA methylation involved in gamete generation	1/2053	20/18722	0.902140524976501	0.956332711989224	KDM1B	1
GO:0045844	positive regulation of striated muscle tissue development	1/2053	20/18722	0.902140524976501	0.956332711989224	MEF2C	1
GO:0048636	positive regulation of muscle organ development	1/2053	20/18722	0.902140524976501	0.956332711989224	MEF2C	1
GO:0048670	regulation of collateral sprouting	1/2053	20/18722	0.902140524976501	0.956332711989224	SPP1	1
GO:0051004	regulation of lipoprotein lipase activity	1/2053	20/18722	0.902140524976501	0.956332711989224	APOC1	1
GO:0060044	negative regulation of cardiac muscle cell proliferation	1/2053	20/18722	0.902140524976501	0.956332711989224	GJA1	1
GO:0061003	positive regulation of dendritic spine morphogenesis	1/2053	20/18722	0.902140524976501	0.956332711989224	ACTR2	1
GO:0070166	enamel mineralization	1/2053	20/18722	0.902140524976501	0.956332711989224	TCIRG1	1
GO:0070932	histone H3 deacetylation	1/2053	20/18722	0.902140524976501	0.956332711989224	HDAC2	1
GO:0071379	cellular response to prostaglandin stimulus	1/2053	20/18722	0.902140524976501	0.956332711989224	PTGER4	1
GO:0071397	cellular response to cholesterol	1/2053	20/18722	0.902140524976501	0.956332711989224	DAG1	1
GO:0072087	renal vesicle development	1/2053	20/18722	0.902140524976501	0.956332711989224	STAT1	1
GO:0097503	sialylation	1/2053	20/18722	0.902140524976501	0.956332711989224	ST3GAL5	1
GO:1990182	exosomal secretion	1/2053	20/18722	0.902140524976501	0.956332711989224	SDCBP	1
GO:0007389	pattern specification process	40/2053	436/18722	0.903779255280156	0.957900641526397	MAFB/MEF2C/ITGAM/LRP2/WLS/ADGRG1/C3/PRKDC/NRP2/BMP7/GALNT11/ENG/NOTCH1/HHEX/NR2F2/LFNG/C1QA/HSPB11/MFNG/BTG2/NRP1/ISL1/NOTCH2/AHI1/FOLR1/PBX1/LRP5/BHLHE40/TRA2B/GLI3/FOXC1/BHLHE41/SMAD5/BASP1/TBX3/IRX2/COBL/GPC3/MEIS2/XRCC2	40
GO:0061053	somite development	6/2053	83/18722	0.904213460277038	0.958191586305586	PRKDC/NOTCH1/LFNG/FOXC1/COBL/XRCC2	6
GO:0006639	acylglycerol metabolic process	10/2053	128/18722	0.906318795552143	0.960253006059131	SORL1/GPX1/C3/APOBR/APOC1/ACSL4/ABHD2/DGKD/MGLL/GK	10
GO:0019731	antibacterial humoral response	4/2053	60/18722	0.907069563764455	0.960709158444259	HLA-A/HLA-E/RNASE6/DEFB1	4
GO:0051965	positive regulation of synapse assembly	4/2053	60/18722	0.907069563764455	0.960709158444259	SEMA4A/TPBG/DLG5/CLSTN1	4
GO:0006643	membrane lipid metabolic process	17/2053	203/18722	0.907456526912415	0.960949375480849	PSAP/HACD3/TECR/ST3GAL5/ORMDL1/PPT1/DEGS1/GPAA1/SPHK1/PGAP2/FUCA1/PLPP3/SERINC2/HEXB/HACD4/DPM2/ITGB8	17
GO:0035567	non-canonical Wnt signaling pathway	5/2053	72/18722	0.907811221506229	0.96115534304524	RNF213/RHOA/ZNRF3/DAAM1/GPC3	5
GO:0042462	eye photoreceptor cell development	2/2053	35/18722	0.909076750468828	0.961961220500787	VEGFA/MYO7A	2
GO:0044273	sulfur compound catabolic process	2/2053	35/18722	0.909076750468828	0.961961220500787	NUDT8/CDO1	2
GO:0045880	positive regulation of smoothened signaling pathway	2/2053	35/18722	0.909076750468828	0.961961220500787	DLG5/GPC3	2
GO:0042908	xenobiotic transport	3/2053	48/18722	0.909213680243327	0.961961220500787	SLC2A1/GJA1/EBP	3
GO:0002088	lens development in camera-type eye	6/2053	84/18722	0.910075522758935	0.962280027190551	VIM/SKIL/FAT1/GATA3/CDK4/DLG1	6
GO:0015844	monoamine transport	6/2053	84/18722	0.910075522758935	0.962280027190551	LILRB1/ACTB/SYK/SLC6A4/SYT7/PARK7	6
GO:0006638	neutral lipid metabolic process	10/2053	129/18722	0.911071389893951	0.962280027190551	SORL1/GPX1/C3/APOBR/APOC1/ACSL4/ABHD2/DGKD/MGLL/GK	10
GO:0001502	cartilage condensation	1/2053	21/18722	0.912882985794769	0.962280027190551	MAPK14	1
GO:0008090	retrograde axonal transport	1/2053	21/18722	0.912882985794769	0.962280027190551	SOD1	1
GO:0016075	rRNA catabolic process	1/2053	21/18722	0.912882985794769	0.962280027190551	EXOSC8	1
GO:0022010	central nervous system myelination	1/2053	21/18722	0.912882985794769	0.962280027190551	TLR2	1
GO:0023019	signal transduction involved in regulation of gene expression	1/2053	21/18722	0.912882985794769	0.962280027190551	PARP1	1
GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	1/2053	21/18722	0.912882985794769	0.962280027190551	STX11	1
GO:0032291	axon ensheathment in central nervous system	1/2053	21/18722	0.912882985794769	0.962280027190551	TLR2	1
GO:0032482	Rab protein signal transduction	1/2053	21/18722	0.912882985794769	0.962280027190551	DENND3	1
GO:0034471	ncRNA 5'-end processing	1/2053	21/18722	0.912882985794769	0.962280027190551	POP7	1
GO:0039702	viral budding via host ESCRT complex	1/2053	21/18722	0.912882985794769	0.962280027190551	CHMP4C	1
GO:0043576	regulation of respiratory gaseous exchange	1/2053	21/18722	0.912882985794769	0.962280027190551	NR4A2	1
GO:0046514	ceramide catabolic process	1/2053	21/18722	0.912882985794769	0.962280027190551	HEXB	1
GO:0050802	circadian sleep/wake cycle, sleep	1/2053	21/18722	0.912882985794769	0.962280027190551	ADRB1	1
GO:0050908	detection of light stimulus involved in visual perception	1/2053	21/18722	0.912882985794769	0.962280027190551	BEST1	1
GO:0050962	detection of light stimulus involved in sensory perception	1/2053	21/18722	0.912882985794769	0.962280027190551	BEST1	1
GO:0097734	extracellular exosome biogenesis	1/2053	21/18722	0.912882985794769	0.962280027190551	SDCBP	1
GO:0099500	vesicle fusion to plasma membrane	1/2053	21/18722	0.912882985794769	0.962280027190551	STX11	1
GO:1901863	positive regulation of muscle tissue development	1/2053	21/18722	0.912882985794769	0.962280027190551	MEF2C	1
GO:0019748	secondary metabolic process	4/2053	61/18722	0.913658121377056	0.962927934000059	ZEB2/AKR7A2/AKR1B1/ARL1	4
GO:1904427	positive regulation of calcium ion transmembrane transport	5/2053	73/18722	0.91386322764148	0.962974950096396	CXCL10/VMP1/KCNE3/CALM2/SLC9A1	5
GO:0007281	germ cell development	24/2053	278/18722	0.915354385911386	0.964376877167395	HMGB2/RARA/PTK2B/LGR5/ASPM/MSH2/CIB1/SLIRP/FBXO5/RPS6/JAM3/BRCA2/SMARCA2/PITHD1/ABHD2/SRPK1/ERCC1/RNF8/ING2/MDK/PTN/HEXB/SMAD5/DEFB1	24
GO:0006352	DNA-templated transcription, initiation	10/2053	130/18722	0.915619047296397	0.964486356000419	HMGB1/TFAM/CDK4/POLR2I/JUN/ERCC1/NAT14/BDP1/ZNF451/SMARCA5	10
GO:0007602	phototransduction	3/2053	49/18722	0.916321447488545	0.964548892093205	GNA11/NMT1/CDS1	3
GO:0007622	rhythmic behavior	3/2053	49/18722	0.916321447488545	0.964548892093205	KCNQ1/ADRB1/ID2	3
GO:0042461	photoreceptor cell development	3/2053	49/18722	0.916321447488545	0.964548892093205	VEGFA/AHI1/MYO7A	3
GO:0048168	regulation of neuronal synaptic plasticity	3/2053	49/18722	0.916321447488545	0.964548892093205	APP/MCTP1/HRAS	3
GO:0008207	C21-steroid hormone metabolic process	2/2053	36/18722	0.91718403692265	0.964610731206994	TSPO/AKR1B1	2
GO:0016180	snRNA processing	2/2053	36/18722	0.91718403692265	0.964610731206994	EXOSC8/TOE1	2
GO:0051955	regulation of amino acid transport	2/2053	36/18722	0.91718403692265	0.964610731206994	ITGB1/RGS2	2
GO:0070306	lens fiber cell differentiation	2/2053	36/18722	0.91718403692265	0.964610731206994	VIM/SKIL	2
GO:0070897	transcription preinitiation complex assembly	2/2053	36/18722	0.91718403692265	0.964610731206994	HMGB1/BDP1	2
GO:0009311	oligosaccharide metabolic process	4/2053	62/18722	0.919826616119633	0.966994250226405	FBP1/FUT8/GAA/HEXB	4
GO:0006661	phosphatidylinositol biosynthetic process	10/2053	131/18722	0.919968066916451	0.966994250226405	SOCS3/GPAA1/PGAP2/SH3YL1/IMPA2/INPP5D/CDS1/CDIPT/PDGFA/DPM2	10
GO:0002029	desensitization of G protein-coupled receptor signaling pathway	1/2053	22/18722	0.922446711272729	0.966994250226405	ARRB2	1
GO:0006359	regulation of transcription by RNA polymerase III	1/2053	22/18722	0.922446711272729	0.966994250226405	PRDX5	1
GO:0007413	axonal fasciculation	1/2053	22/18722	0.922446711272729	0.966994250226405	NRP1	1
GO:0010866	regulation of triglyceride biosynthetic process	1/2053	22/18722	0.922446711272729	0.966994250226405	C3	1
GO:0021904	dorsal/ventral neural tube patterning	1/2053	22/18722	0.922446711272729	0.966994250226405	GLI3	1
GO:0022401	negative adaptation of signaling pathway	1/2053	22/18722	0.922446711272729	0.966994250226405	ARRB2	1
GO:0030277	maintenance of gastrointestinal epithelium	1/2053	22/18722	0.922446711272729	0.966994250226405	TLR4	1
GO:0032098	regulation of appetite	1/2053	22/18722	0.922446711272729	0.966994250226405	NENF	1
GO:0032402	melanosome transport	1/2053	22/18722	0.922446711272729	0.966994250226405	MYO5A	1
GO:0042749	regulation of circadian sleep/wake cycle	1/2053	22/18722	0.922446711272729	0.966994250226405	ADRB1	1
GO:0045048	protein insertion into ER membrane	1/2053	22/18722	0.922446711272729	0.966994250226405	CCDC47	1
GO:0045540	regulation of cholesterol biosynthetic process	1/2053	22/18722	0.922446711272729	0.966994250226405	SOD1	1
GO:0046058	cAMP metabolic process	1/2053	22/18722	0.922446711272729	0.966994250226405	PDE4A	1
GO:0106030	neuron projection fasciculation	1/2053	22/18722	0.922446711272729	0.966994250226405	NRP1	1
GO:0106118	regulation of sterol biosynthetic process	1/2053	22/18722	0.922446711272729	0.966994250226405	SOD1	1
GO:0007632	visual behavior	3/2053	50/18722	0.922918147389694	0.966994250226405	APP/ITGB1/MEIS2	3
GO:0046460	neutral lipid biosynthetic process	3/2053	50/18722	0.922918147389694	0.966994250226405	C3/ACSL4/GK	3
GO:0046463	acylglycerol biosynthetic process	3/2053	50/18722	0.922918147389694	0.966994250226405	C3/ACSL4/GK	3
GO:0099054	presynapse assembly	3/2053	50/18722	0.922918147389694	0.966994250226405	APP/SDCBP/EIF4G1	3
GO:0000154	rRNA modification	2/2053	37/18722	0.924607668924815	0.966994250226405	NHP2/FBL	2
GO:0003016	respiratory system process	2/2053	37/18722	0.924607668924815	0.966994250226405	ADH5/GAA	2
GO:0007340	acrosome reaction	2/2053	37/18722	0.924607668924815	0.966994250226405	SPESP1/ABHD2	2
GO:0014904	myotube cell development	2/2053	37/18722	0.924607668924815	0.966994250226405	GPX1/HOMER1	2
GO:0032885	regulation of polysaccharide biosynthetic process	2/2053	37/18722	0.924607668924815	0.966994250226405	TGFB1/INSR	2
GO:0033363	secretory granule organization	2/2053	37/18722	0.924607668924815	0.966994250226405	SRGN/LYST	2
GO:0046473	phosphatidic acid metabolic process	2/2053	37/18722	0.924607668924815	0.966994250226405	AGPAT2/DGKD	2
GO:0048009	insulin-like growth factor receptor signaling pathway	2/2053	37/18722	0.924607668924815	0.966994250226405	CRIM1/IGF1R	2
GO:0050775	positive regulation of dendrite morphogenesis	2/2053	37/18722	0.924607668924815	0.966994250226405	ACTR2/OBSL1	2
GO:0060428	lung epithelium development	2/2053	37/18722	0.924607668924815	0.966994250226405	KLF2/YAP1	2
GO:0097484	dendrite extension	2/2053	37/18722	0.924607668924815	0.966994250226405	CXCR4/ITSN2	2
GO:0016101	diterpenoid metabolic process	6/2053	87/18722	0.925831510209592	0.968105448110414	EGFR/LRP2/ADH5/AKR1B1/ALDH1A1/SCPEP1	6
GO:0016197	endosomal transport	19/2053	230/18722	0.927937879998801	0.969781784945257	WAS/SORL1/LRRK2/TINAGL1/NSG1/LYST/RHOBTB3/ITSN2/SNX4/STX10/CORO1C/DPY30/CHMP4C/VPS25/VCP/PICALM/ARL1/EEA1/STX6	19
GO:0009584	detection of visible light	3/2053	51/18722	0.929035280538978	0.969781784945257	GNA11/BEST1/NMT1	3
GO:0010874	regulation of cholesterol efflux	3/2053	51/18722	0.929035280538978	0.969781784945257	NFKBIA/TREM2/PPARG	3
GO:0050982	detection of mechanical stimulus	3/2053	51/18722	0.929035280538978	0.969781784945257	CXCR4/KCNQ1/PTK2	3
GO:0060632	regulation of microtubule-based movement	3/2053	51/18722	0.929035280538978	0.969781784945257	CATSPER1/CFAP20/DEFB1	3
GO:0006813	potassium ion transport	20/2053	241/18722	0.929332115870001	0.969781784945257	FLNA/FXYD3/ITGB1/KCNAB2/TREM2/KCNQ1/PTK2B/KCNK6/KCNMB1/KCNE3/CHP1/GJA5/ANK3/CD63/KCNN4/YWHAE/SLC9A1/DLG1/AKAP9/SLC1A3	20
GO:0000966	RNA 5'-end processing	1/2053	23/18722	0.930960984093964	0.969781784945257	POP7	1
GO:0001919	regulation of receptor recycling	1/2053	23/18722	0.930960984093964	0.969781784945257	NSG1	1
GO:0006833	water transport	1/2053	23/18722	0.930960984093964	0.969781784945257	AQP9	1
GO:0007130	synaptonemal complex assembly	1/2053	23/18722	0.930960984093964	0.969781784945257	RAD21	1
GO:0021895	cerebral cortex neuron differentiation	1/2053	23/18722	0.930960984093964	0.969781784945257	RAC3	1
GO:0023058	adaptation of signaling pathway	1/2053	23/18722	0.930960984093964	0.969781784945257	ARRB2	1
GO:0032401	establishment of melanosome localization	1/2053	23/18722	0.930960984093964	0.969781784945257	MYO5A	1
GO:0033139	regulation of peptidyl-serine phosphorylation of STAT protein	1/2053	23/18722	0.930960984093964	0.969781784945257	PWP1	1
GO:0034105	positive regulation of tissue remodeling	1/2053	23/18722	0.930960984093964	0.969781784945257	IL18	1
GO:0035988	chondrocyte proliferation	1/2053	23/18722	0.930960984093964	0.969781784945257	GOLGB1	1
GO:0042438	melanin biosynthetic process	1/2053	23/18722	0.930960984093964	0.969781784945257	ZEB2	1
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	1/2053	23/18722	0.930960984093964	0.969781784945257	VPS25	1
GO:0051446	positive regulation of meiotic cell cycle	1/2053	23/18722	0.930960984093964	0.969781784945257	RAD51AP1	1
GO:0051590	positive regulation of neurotransmitter transport	1/2053	23/18722	0.930960984093964	0.969781784945257	ITGB1	1
GO:0140112	extracellular vesicle biogenesis	1/2053	23/18722	0.930960984093964	0.969781784945257	SDCBP	1
GO:0017156	calcium-ion regulated exocytosis	4/2053	64/18722	0.930990513547447	0.969781784945257	NOTCH1/GNAI2/SYT7/SCIN	4
GO:0035136	forelimb morphogenesis	2/2053	38/18722	0.93140000636838	0.970039930256948	TFAP2A/TBX3	2
GO:0006664	glycolipid metabolic process	7/2053	100/18722	0.93199590856709	0.970323694499834	ST3GAL5/GPAA1/PGAP2/FUCA1/HEXB/DPM2/ITGB8	7
GO:0019218	regulation of steroid metabolic process	7/2053	100/18722	0.93199590856709	0.970323694499834	TSPO/TNF/SOD1/ACADVL/APOC1/SF1/LDLRAP1	7
GO:0006367	transcription initiation from RNA polymerase II promoter	5/2053	77/18722	0.934709165050294	0.972979699913561	HMGB1/CDK4/POLR2I/ERCC1/ZNF451	5
GO:0046513	ceramide biosynthetic process	4/2053	65/18722	0.936027863438872	0.974183379121115	ST3GAL5/ORMDL1/DEGS1/SPHK1	4
GO:0009101	glycoprotein biosynthetic process	27/2053	317/18722	0.937081144819665	0.974601156265325	RPN2/DDOST/TUSC3/SERP1/ST3GAL5/GALNT11/EXTL2/CHPF/HBEGF/PAWR/ITM2C/CHP1/CHST15/CHST14/FUT8/C1GALT1/DSE/TMTC3/GXYLT1/AGO2/C1GALT1C1/B3GAT3/GALNT18/GFPT1/DPM2/HS6ST2/ALG8	27
GO:0001941	postsynaptic membrane organization	2/2053	39/18722	0.937610153004257	0.974601156265325	CHRNB1/PTN	2
GO:0090207	regulation of triglyceride metabolic process	2/2053	39/18722	0.937610153004257	0.974601156265325	SORL1/C3	2
GO:2000785	regulation of autophagosome assembly	2/2053	39/18722	0.937610153004257	0.974601156265325	LRRK2/RALB	2
GO:0000395	mRNA 5'-splice site recognition	1/2053	24/18722	0.938540913483508	0.974601156265325	PSIP1	1
GO:0006582	melanin metabolic process	1/2053	24/18722	0.938540913483508	0.974601156265325	ZEB2	1
GO:0018230	peptidyl-L-cysteine S-palmitoylation	1/2053	24/18722	0.938540913483508	0.974601156265325	ZDHHC12	1
GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine	1/2053	24/18722	0.938540913483508	0.974601156265325	ZDHHC12	1
GO:0022410	circadian sleep/wake cycle process	1/2053	24/18722	0.938540913483508	0.974601156265325	ADRB1	1
GO:0051123	RNA polymerase II preinitiation complex assembly	1/2053	24/18722	0.938540913483508	0.974601156265325	HMGB1	1
GO:0051647	nucleus localization	1/2053	24/18722	0.938540913483508	0.974601156265325	SYNE2	1
GO:0098743	cell aggregation	1/2053	24/18722	0.938540913483508	0.974601156265325	MAPK14	1
GO:0120255	olefinic compound biosynthetic process	1/2053	24/18722	0.938540913483508	0.974601156265325	HSD17B1	1
GO:1901616	organic hydroxy compound catabolic process	5/2053	78/18722	0.939158790476734	0.975074016760755	ALDH2/COMT/SULT1A1/IMPA2/GK	5
GO:0071715	icosanoid transport	3/2053	53/18722	0.939950291086223	0.975603228602746	IL1B/SYK/PTGES	3
GO:0006672	ceramide metabolic process	7/2053	102/18722	0.939993710758746	0.975603228602746	ST3GAL5/ORMDL1/DEGS1/SPHK1/PLPP3/HEXB/ITGB8	7
GO:0042446	hormone biosynthetic process	4/2053	66/18722	0.940728961491485	0.976197469551869	TSPO/HSD17B1/AKR1B1/HSD17B11	4
GO:0032094	response to food	2/2053	40/18722	0.943284040601296	0.977129136978547	SLC16A1/NENF	2
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	2/2053	40/18722	0.943284040601296	0.977129136978547	CXCL10/CALM2	2
GO:0097352	autophagosome maturation	2/2053	40/18722	0.943284040601296	0.977129136978547	VMP1/VCP	2
GO:0031929	TOR signaling	9/2053	126/18722	0.943312501149407	0.977129136978547	NCKAP1L/TREM2/DDIT4/CCDC88A/LAMTOR4/RHEB/GATA3/RPS6/SLC38A9	9
GO:0030148	sphingolipid biosynthetic process	7/2053	103/18722	0.943671410877076	0.977129136978547	HACD3/ST3GAL5/ORMDL1/DEGS1/SPHK1/PLPP3/HACD4	7
GO:0010524	positive regulation of calcium ion transport into cytosol	3/2053	54/18722	0.944804530216039	0.977129136978547	CXCL10/P2RX7/CALM2	3
GO:0014888	striated muscle adaptation	3/2053	54/18722	0.944804530216039	0.977129136978547	EZH2/CAMK2G/LMNA	3
GO:0042471	ear morphogenesis	8/2053	115/18722	0.944903359209879	0.977129136978547	MAFB/SOD1/KCNQ1/TFAP2A/GATA3/ATP6V1B1/TRIOBP/MYO7A	8
GO:0009583	detection of light stimulus	4/2053	67/18722	0.945113009973051	0.977129136978547	GNA11/BEST1/NMT1/CDS1	4
GO:0007274	neuromuscular synaptic transmission	1/2053	25/18722	0.945288988390897	0.977129136978547	CHRNB1	1
GO:0015874	norepinephrine transport	1/2053	25/18722	0.945288988390897	0.977129136978547	ACTB	1
GO:0032331	negative regulation of chondrocyte differentiation	1/2053	25/18722	0.945288988390897	0.977129136978547	EFEMP1	1
GO:0032400	melanosome localization	1/2053	25/18722	0.945288988390897	0.977129136978547	MYO5A	1
GO:0032925	regulation of activin receptor signaling pathway	1/2053	25/18722	0.945288988390897	0.977129136978547	FKBP1A	1
GO:0036315	cellular response to sterol	1/2053	25/18722	0.945288988390897	0.977129136978547	DAG1	1
GO:0042730	fibrinolysis	1/2053	25/18722	0.945288988390897	0.977129136978547	SERPING1	1
GO:0044550	secondary metabolite biosynthetic process	1/2053	25/18722	0.945288988390897	0.977129136978547	ZEB2	1
GO:0045822	negative regulation of heart contraction	1/2053	25/18722	0.945288988390897	0.977129136978547	JAK2	1
GO:0046339	diacylglycerol metabolic process	1/2053	25/18722	0.945288988390897	0.977129136978547	DGKD	1
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	1/2053	25/18722	0.945288988390897	0.977129136978547	ERCC1	1
GO:1902932	positive regulation of alcohol biosynthetic process	1/2053	25/18722	0.945288988390897	0.977129136978547	PTAFR	1
GO:2000311	regulation of AMPA receptor activity	1/2053	25/18722	0.945288988390897	0.977129136978547	MEF2C	1
GO:0009582	detection of abiotic stimulus	10/2053	138/18722	0.945372440026744	0.977129136978547	CXCR4/ARRB2/NR2F6/KCNQ1/GNA11/BEST1/NMT1/TIMELESS/CDS1/PTK2	10
GO:0006486	protein glycosylation	18/2053	226/18722	0.945941483392693	0.977380558008637	RPN2/DDOST/TUSC3/SERP1/ST3GAL5/GALNT11/EXTL2/CHP1/FUT8/C1GALT1/TMTC3/GXYLT1/C1GALT1C1/B3GAT3/GALNT18/GFPT1/DPM2/ALG8	18
GO:0043413	macromolecule glycosylation	18/2053	226/18722	0.945941483392693	0.977380558008637	RPN2/DDOST/TUSC3/SERP1/ST3GAL5/GALNT11/EXTL2/CHP1/FUT8/C1GALT1/TMTC3/GXYLT1/C1GALT1C1/B3GAT3/GALNT18/GFPT1/DPM2/ALG8	18
GO:0002251	organ or tissue specific immune response	2/2053	41/18722	0.948464533802011	0.979035808449366	IL6R/DEFB1	2
GO:0048286	lung alveolus development	2/2053	41/18722	0.948464533802011	0.979035808449366	PDGFA/ASXL1	2
GO:1901385	regulation of voltage-gated calcium channel activity	2/2053	41/18722	0.948464533802011	0.979035808449366	KCNE3/DMD	2
GO:0009247	glycolipid biosynthetic process	4/2053	68/18722	0.949198460513027	0.979035808449366	ST3GAL5/GPAA1/PGAP2/DPM2	4
GO:1904888	cranial skeletal system development	4/2053	68/18722	0.949198460513027	0.979035808449366	SLC39A1/TFAP2A/MSX2/GLI3	4
GO:0001523	retinoid metabolic process	5/2053	81/18722	0.950916111046163	0.979035808449366	LRP2/ADH5/AKR1B1/ALDH1A1/SCPEP1	5
GO:0003416	endochondral bone growth	1/2053	26/18722	0.951296460543301	0.979035808449366	RARA	1
GO:0006517	protein deglycosylation	1/2053	26/18722	0.951296460543301	0.979035808449366	PARK7	1
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1/2053	26/18722	0.951296460543301	0.979035808449366	SEC63	1
GO:0015985	energy coupled proton transport, down electrochemical gradient	1/2053	26/18722	0.951296460543301	0.979035808449366	STOML2	1
GO:0015986	ATP synthesis coupled proton transport	1/2053	26/18722	0.951296460543301	0.979035808449366	STOML2	1
GO:0018027	peptidyl-lysine dimethylation	1/2053	26/18722	0.951296460543301	0.979035808449366	SMYD2	1
GO:0031167	rRNA methylation	1/2053	26/18722	0.951296460543301	0.979035808449366	FBL	1
GO:0034063	stress granule assembly	1/2053	26/18722	0.951296460543301	0.979035808449366	RPS23	1
GO:0042537	benzene-containing compound metabolic process	1/2053	26/18722	0.951296460543301	0.979035808449366	KYNU	1
GO:0043501	skeletal muscle adaptation	1/2053	26/18722	0.951296460543301	0.979035808449366	CAMK2G	1
GO:0046755	viral budding	1/2053	26/18722	0.951296460543301	0.979035808449366	CHMP4C	1
GO:0048499	synaptic vesicle membrane organization	1/2053	26/18722	0.951296460543301	0.979035808449366	STX11	1
GO:0060219	camera-type eye photoreceptor cell differentiation	1/2053	26/18722	0.951296460543301	0.979035808449366	PTN	1
GO:0070193	synaptonemal complex organization	1/2053	26/18722	0.951296460543301	0.979035808449366	RAD21	1
GO:0071425	hematopoietic stem cell proliferation	1/2053	26/18722	0.951296460543301	0.979035808449366	RUNX1	1
GO:1901071	glucosamine-containing compound metabolic process	1/2053	26/18722	0.951296460543301	0.979035808449366	EXTL2	1
GO:1903523	negative regulation of blood circulation	1/2053	26/18722	0.951296460543301	0.979035808449366	JAK2	1
GO:0042445	hormone metabolic process	17/2053	218/18722	0.952394988518961	0.979998273214502	TSPO/CTSB/SPP1/CTSL/CTSZ/MME/IL4I1/HSD17B1/COMT/ENPEP/SULT1A1/AKR1B1/ALDH1A1/SCPEP1/GATA3/HSD17B11/PLEKHA1	17
GO:0050810	regulation of steroid biosynthetic process	4/2053	69/18722	0.953003002844809	0.980395985934515	TSPO/TNF/SOD1/SF1	4
GO:0048489	synaptic vesicle transport	2/2053	42/18722	0.95319155012748	0.980395985934515	LRRK2/PICALM	2
GO:0070085	glycosylation	19/2053	240/18722	0.953271696990327	0.980395985934515	RPN2/DDOST/TUSC3/SERP1/ST3GAL5/GALNT11/EXTL2/CHP1/FUOM/FUT8/C1GALT1/TMTC3/GXYLT1/C1GALT1C1/B3GAT3/GALNT18/GFPT1/DPM2/ALG8	19
GO:0006687	glycosphingolipid metabolic process	3/2053	56/18722	0.95343722132316	0.980398171026385	ST3GAL5/HEXB/ITGB8	3
GO:0046889	positive regulation of lipid biosynthetic process	5/2053	82/18722	0.954350606377883	0.981169232054026	CD74/TNF/IL1B/CHP1/MID1IP1	5
GO:0015850	organic hydroxy compound transport	23/2053	284/18722	0.955759189122759	0.981182654679017	TSPO/MSR1/LILRB1/SLC16A3/NPC2/ACTB/SPP1/AQP9/CD36/NFKBIA/SYK/TREM2/KCNQ1/APOC1/SLC6A4/SYT7/SLC16A1/PARK7/C1QTNF1/LIMA1/LDLRAP1/PPARG/SLC10A3	23
GO:0046467	membrane lipid biosynthetic process	10/2053	142/18722	0.956459460833306	0.981182654679017	HACD3/ST3GAL5/ORMDL1/DEGS1/GPAA1/SPHK1/PGAP2/PLPP3/HACD4/DPM2	10
GO:0002227	innate immune response in mucosa	1/2053	27/18722	0.95664457599605	0.981182654679017	DEFB1	1
GO:0007628	adult walking behavior	1/2053	27/18722	0.95664457599605	0.981182654679017	ARRB2	1
GO:0010894	negative regulation of steroid biosynthetic process	1/2053	27/18722	0.95664457599605	0.981182654679017	SOD1	1
GO:0018195	peptidyl-arginine modification	1/2053	27/18722	0.95664457599605	0.981182654679017	PARK7	1
GO:0034377	plasma lipoprotein particle assembly	1/2053	27/18722	0.95664457599605	0.981182654679017	APOC1	1
GO:0034453	microtubule anchoring	1/2053	27/18722	0.95664457599605	0.981182654679017	DAG1	1
GO:0042501	serine phosphorylation of STAT protein	1/2053	27/18722	0.95664457599605	0.981182654679017	PWP1	1
GO:0042745	circadian sleep/wake cycle	1/2053	27/18722	0.95664457599605	0.981182654679017	ADRB1	1
GO:0046337	phosphatidylethanolamine metabolic process	1/2053	27/18722	0.95664457599605	0.981182654679017	PISD	1
GO:0051953	negative regulation of amine transport	1/2053	27/18722	0.95664457599605	0.981182654679017	RGS2	1
GO:2000463	positive regulation of excitatory postsynaptic potential	1/2053	27/18722	0.95664457599605	0.981182654679017	PTK2B	1
GO:0048705	skeletal system morphogenesis	17/2053	220/18722	0.956653088312041	0.981182654679017	MEF2C/FBN2/FGR/RARA/BMP7/SERPINH1/SLC39A1/TFAP2A/LRP5/ACP5/MSX2/ARID5B/DLG1/GLI3/FOXC1/PLEKHA1/MAPK14	17
GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	2/2053	43/18722	0.957502190551569	0.981550169709451	FXYD5/SELL	2
GO:0021983	pituitary gland development	2/2053	43/18722	0.957502190551569	0.981550169709451	CDH1/ISL1	2
GO:0042181	ketone biosynthetic process	2/2053	43/18722	0.957502190551569	0.981550169709451	HSD17B1/COQ4	2
GO:0098659	inorganic cation import across plasma membrane	7/2053	108/18722	0.959213174984704	0.982968240804137	SLC8A1/KCNQ1/TRPV2/SLC39A10/TRPM2/SLC9A1/DLG1	7
GO:0099587	inorganic ion import across plasma membrane	7/2053	108/18722	0.959213174984704	0.982968240804137	SLC8A1/KCNQ1/TRPV2/SLC39A10/TRPM2/SLC9A1/DLG1	7
GO:0003156	regulation of animal organ formation	1/2053	28/18722	0.961405671769257	0.98454241860651	BMP7	1
GO:0030262	apoptotic nuclear changes	1/2053	28/18722	0.961405671769257	0.98454241860651	TOP2A	1
GO:0050996	positive regulation of lipid catabolic process	1/2053	28/18722	0.961405671769257	0.98454241860651	IL1B	1
GO:0090659	walking behavior	1/2053	28/18722	0.961405671769257	0.98454241860651	ARRB2	1
GO:0055088	lipid homeostasis	12/2053	167/18722	0.96160619080946	0.984579717552348	NPC2/CD24/TREM2/TMEM97/ORMDL1/ASGR2/LRP5/LIMA1/IL18/MYLIP/LDLRAP1/PPARG	12
GO:0032410	negative regulation of transporter activity	7/2053	109/18722	0.961812260043423	0.984622685592994	CAMK2D/KCNE3/CALM2/C4orf3/ANK3/GOPC/YWHAE	7
GO:0048706	embryonic skeletal system development	8/2053	121/18722	0.96199542696305	0.984642197505681	BMP7/SLC39A1/TFAP2A/SULF2/KIAA1217/PBX1/DLG1/GLI3	8
GO:0000271	polysaccharide biosynthetic process	4/2053	72/18722	0.962896587256567	0.985060447321296	TGFB1/AGL/UGP2/INSR	4
GO:0001736	establishment of planar polarity	4/2053	72/18722	0.962896587256567	0.985060447321296	RHOA/ZNRF3/DAAM1/GPC3	4
GO:0007164	establishment of tissue polarity	4/2053	72/18722	0.962896587256567	0.985060447321296	RHOA/ZNRF3/DAAM1/GPC3	4
GO:0007416	synapse assembly	13/2053	179/18722	0.963078362750918	0.985078448091631	MEF2C/TLR2/ABI3/CDH1/APP/SEMA4A/ZDHHC12/TPBG/DLG5/SDCBP/OBSL1/EIF4G1/CLSTN1	13
GO:2001258	negative regulation of cation channel activity	3/2053	59/18722	0.964049016963498	0.985884530241294	KCNE3/CALM2/ANK3	3
GO:0043583	ear development	16/2053	213/18722	0.964195070575986	0.985884530241294	MAFB/SOD1/NOTCH1/KCNQ1/LGR5/MCM2/TFAP2A/CCNA2/MCOLN3/AHI1/GATA3/ESRP1/ATP6V1B1/GLI3/TRIOBP/MYO7A	16
GO:0005979	regulation of glycogen biosynthetic process	1/2053	29/18722	0.965644152343651	0.985951098374111	INSR	1
GO:0006688	glycosphingolipid biosynthetic process	1/2053	29/18722	0.965644152343651	0.985951098374111	ST3GAL5	1
GO:0010962	regulation of glucan biosynthetic process	1/2053	29/18722	0.965644152343651	0.985951098374111	INSR	1
GO:0031069	hair follicle morphogenesis	1/2053	29/18722	0.965644152343651	0.985951098374111	NOTCH1	1
GO:0032372	negative regulation of sterol transport	1/2053	29/18722	0.965644152343651	0.985951098374111	APOC1	1
GO:0032375	negative regulation of cholesterol transport	1/2053	29/18722	0.965644152343651	0.985951098374111	APOC1	1
GO:0098868	bone growth	1/2053	29/18722	0.965644152343651	0.985951098374111	RARA	1
GO:1902430	negative regulation of amyloid-beta formation	1/2053	29/18722	0.965644152343651	0.985951098374111	SORL1	1
GO:0032456	endocytic recycling	4/2053	73/18722	0.965739100857441	0.985951098374111	SORL1/NSG1/SNX4/STX6	4
GO:0009581	detection of external stimulus	9/2053	135/18722	0.966870049964231	0.98693778492436	CXCR4/ARRB2/NR2F6/KCNQ1/GNA11/BEST1/NMT1/CDS1/PTK2	9
GO:0007631	feeding behavior	6/2053	99/18722	0.967134774816633	0.987040083160367	FOS/RETN/APP/STAT3/CFAP20/EIF2AK4	6
GO:0046839	phospholipid dephosphorylation	2/2053	46/18722	0.968267526804982	0.98783180947803	PLPP3/INPP5D	2
GO:0071827	plasma lipoprotein particle organization	2/2053	46/18722	0.968267526804982	0.98783180947803	PLA2G7/APOC1	2
GO:0007029	endoplasmic reticulum organization	5/2053	87/18722	0.9684527055593	0.98783180947803	LRRK2/LMAN1/CCDC47/TMEM170A/SEC31A	5
GO:0007368	determination of left/right symmetry	8/2053	124/18722	0.968605451770592	0.98783180947803	MEF2C/GALNT11/ENG/NOTCH1/NOTCH2/AHI1/FOLR1/TBX3	8
GO:0001676	long-chain fatty acid metabolic process	7/2053	112/18722	0.968733727828121	0.98783180947803	GPX1/ALOX5/GSTP1/SLC27A2/TBXAS1/ACSL4/MGLL	7
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	1/2053	30/18722	0.969417359171795	0.988025166473716	TOP2A	1
GO:0010669	epithelial structure maintenance	1/2053	30/18722	0.969417359171795	0.988025166473716	TLR4	1
GO:0045939	negative regulation of steroid metabolic process	1/2053	30/18722	0.969417359171795	0.988025166473716	SOD1	1
GO:0030199	collagen fibril organization	3/2053	61/18722	0.969809477665466	0.988256940555842	COL14A1/SERPINH1/FOXC1	3
GO:0048512	circadian behavior	2/2053	47/18722	0.971232212815964	0.98937067519453	ADRB1/ID2	2
GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	2/2053	47/18722	0.971232212815964	0.98937067519453	VEGFA/HMOX1	2
GO:0050482	arachidonic acid secretion	1/2053	31/18722	0.972776344920794	0.990271134971966	SYK	1
GO:0055075	potassium ion homeostasis	1/2053	31/18722	0.972776344920794	0.990271134971966	ATP6V1B1	1
GO:0065005	protein-lipid complex assembly	1/2053	31/18722	0.972776344920794	0.990271134971966	APOC1	1
GO:1903963	arachidonate transport	1/2053	31/18722	0.972776344920794	0.990271134971966	SYK	1
GO:0071805	potassium ion transmembrane transport	16/2053	219/18722	0.973512917508445	0.990852842247782	FLNA/ITGB1/KCNAB2/TREM2/KCNQ1/KCNK6/KCNMB1/KCNE3/ANK3/CD63/KCNN4/YWHAE/SLC9A1/DLG1/AKAP9/SLC1A3	16
GO:0019228	neuronal action potential	1/2053	32/18722	0.975766562880112	0.992473194995876	ANK3	1
GO:0042044	fluid transport	1/2053	32/18722	0.975766562880112	0.992473194995876	AQP9	1
GO:0042219	cellular modified amino acid catabolic process	1/2053	32/18722	0.975766562880112	0.992473194995876	PCYOX1	1
GO:0046856	phosphatidylinositol dephosphorylation	1/2053	32/18722	0.975766562880112	0.992473194995876	INPP5D	1
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	2/2053	49/18722	0.976380041956685	0.992760591720066	FBXO6/SKP2	2
GO:1990573	potassium ion import across plasma membrane	2/2053	49/18722	0.976380041956685	0.992760591720066	KCNQ1/DLG1	2
GO:0042147	retrograde transport, endosome to Golgi	5/2053	91/18722	0.976705221810653	0.992889482592881	LRRK2/RHOBTB3/STX10/ARL1/STX6	5
GO:0098930	axonal transport	3/2053	64/18722	0.976837769290962	0.992889482592881	SOD1/ARMCX3/KIF4A	3
GO:0032006	regulation of TOR signaling	6/2053	104/18722	0.977011668363698	0.992898036954978	NCKAP1L/TREM2/DDIT4/LAMTOR4/RHEB/SLC38A9	6
GO:0007286	spermatid development	11/2053	165/18722	0.977661018304568	0.993189398486175	HMGB2/CIB1/SLIRP/JAM3/SMARCA2/PITHD1/ABHD2/SRPK1/RNF8/ING2/DEFB1	11
GO:0032228	regulation of synaptic transmission, GABAergic	1/2053	33/18722	0.978428480825919	0.993189398486175	ZDHHC12	1
GO:0110110	positive regulation of animal organ morphogenesis	1/2053	33/18722	0.978428480825919	0.993189398486175	GATA3	1
GO:0008089	anterograde axonal transport	2/2053	50/18722	0.978607620896977	0.993189398486175	SOD1/KIF4A	2
GO:0015872	dopamine transport	2/2053	50/18722	0.978607620896977	0.993189398486175	SYT7/PARK7	2
GO:0042572	retinol metabolic process	2/2053	50/18722	0.978607620896977	0.993189398486175	AKR1B1/ALDH1A1	2
GO:0071825	protein-lipid complex subunit organization	2/2053	50/18722	0.978607620896977	0.993189398486175	PLA2G7/APOC1	2
GO:0016079	synaptic vesicle exocytosis	6/2053	105/18722	0.978622620641711	0.993189398486175	LRRK2/STX11/PRKCB/SYT7/RAP1A/CHRNA5	6
GO:0033692	cellular polysaccharide biosynthetic process	3/2053	65/18722	0.978812442154773	0.993214045819151	AGL/UGP2/INSR	3
GO:0010970	transport along microtubule	10/2053	155/18722	0.979979851748111	0.994230488753579	APP/SOD1/HSPB11/UBB/HSPA8/ARMCX3/ARHGAP21/LRPPRC/KIF4A/PURA	10
GO:0042573	retinoic acid metabolic process	1/2053	34/18722	0.980798127616244	0.994388098292914	SCPEP1	1
GO:0048854	brain morphogenesis	1/2053	34/18722	0.980798127616244	0.994388098292914	SLC6A4	1
GO:0070050	neuron cellular homeostasis	1/2053	34/18722	0.980798127616244	0.994388098292914	ATP2B1	1
GO:0098664	G protein-coupled serotonin receptor signaling pathway	1/2053	34/18722	0.980798127616244	0.994388098292914	HRH2	1
GO:0048704	embryonic skeletal system morphogenesis	5/2053	94/18722	0.981520881060963	0.994952743092715	BMP7/SLC39A1/TFAP2A/DLG1/GLI3	5
GO:0008589	regulation of smoothened signaling pathway	4/2053	81/18722	0.982161805276803	0.995181484865291	DLG5/GLI3/VCP/GPC3	4
GO:0048814	regulation of dendrite morphogenesis	3/2053	67/18722	0.982290609886833	0.995181484865291	ID1/ACTR2/OBSL1	3
GO:0009855	determination of bilateral symmetry	8/2053	133/18722	0.982651479110412	0.995181484865291	MEF2C/GALNT11/ENG/NOTCH1/NOTCH2/AHI1/FOLR1/TBX3	8
GO:0006958	complement activation, classical pathway	6/2053	108/18722	0.982847454067752	0.995181484865291	C3/CD46/TREM2/C1QA/C1QBP/SERPING1	6
GO:0019068	virion assembly	1/2053	35/18722	0.982907579885286	0.995181484865291	CHMP4C	1
GO:0032350	regulation of hormone metabolic process	1/2053	35/18722	0.982907579885286	0.995181484865291	GATA3	1
GO:1905898	positive regulation of response to endoplasmic reticulum stress	1/2053	35/18722	0.982907579885286	0.995181484865291	PMAIP1	1
GO:0008543	fibroblast growth factor receptor signaling pathway	4/2053	82/18722	0.983588020604952	0.995570745137493	SULF2/GATA3/SHCBP1/GPC1	4
GO:0009799	specification of symmetry	8/2053	134/18722	0.98378624498243	0.995570745137493	MEF2C/GALNT11/ENG/NOTCH1/NOTCH2/AHI1/FOLR1/TBX3	8
GO:0097479	synaptic vesicle localization	2/2053	53/18722	0.984135464325877	0.995570745137493	LRRK2/PICALM	2
GO:0006699	bile acid biosynthetic process	1/2053	36/18722	0.984785395398504	0.995570745137493	SLC27A2	1
GO:0007031	peroxisome organization	1/2053	36/18722	0.984785395398504	0.995570745137493	FIS1	1
GO:0014046	dopamine secretion	1/2053	36/18722	0.984785395398504	0.995570745137493	SYT7	1
GO:0014059	regulation of dopamine secretion	1/2053	36/18722	0.984785395398504	0.995570745137493	SYT7	1
GO:0042755	eating behavior	1/2053	36/18722	0.984785395398504	0.995570745137493	STAT3	1
GO:0051354	negative regulation of oxidoreductase activity	1/2053	36/18722	0.984785395398504	0.995570745137493	LRRK2	1
GO:0048515	spermatid differentiation	11/2053	172/18722	0.985371892727476	0.995995848444214	HMGB2/CIB1/SLIRP/JAM3/SMARCA2/PITHD1/ABHD2/SRPK1/RNF8/ING2/DEFB1	11
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	2/2053	54/18722	0.985648192560871	0.996107319414726	VEGFA/HMOX1	2
GO:0021532	neural tube patterning	1/2053	37/18722	0.986456998911662	0.996421211021881	GLI3	1
GO:0042178	xenobiotic catabolic process	1/2053	37/18722	0.986456998911662	0.996421211021881	NUDT15	1
GO:0051954	positive regulation of amine transport	1/2053	37/18722	0.986456998911662	0.996421211021881	ITGB1	1
GO:0072384	organelle transport along microtubule	4/2053	85/18722	0.987245559702131	0.99704988355711	UBB/ARMCX3/ARHGAP21/LRPPRC	4
GO:0002385	mucosal immune response	1/2053	38/18722	0.987945025737156	0.997588380077909	DEFB1	1
GO:0006910	phagocytosis, recognition	5/2053	100/18722	0.988485500281007	0.99796617898133	FCN1/CLEC7A/COLEC12/CD36/TREM2	5
GO:0099003	vesicle-mediated transport in synapse	13/2053	200/18722	0.988692628498881	0.998007363895237	ACTB/LRRK2/STX11/NSG1/PRKCB/ITSN2/SYT7/RAP1A/NUMB/CHRNA5/PICALM/AP2M1/CLSTN1	13
GO:0007210	serotonin receptor signaling pathway	1/2053	39/18722	0.98926962765118	0.998253912866983	HRH2	1
GO:0021587	cerebellum morphogenesis	1/2053	39/18722	0.98926962765118	0.998253912866983	HSPA5	1
GO:0051937	catecholamine transport	3/2053	73/18722	0.989742989230541	0.998563634670127	ACTB/SYT7/PARK7	3
GO:0009187	cyclic nucleotide metabolic process	1/2053	40/18722	0.990448745267844	0.998939732998329	PDE4A	1
GO:0042073	intraciliary transport	1/2053	40/18722	0.990448745267844	0.998939732998329	HSPB11	1
GO:0006418	tRNA aminoacylation for protein translation	1/2053	41/18722	0.991498350554489	0.999339302666251	IARS2	1
GO:0030488	tRNA methylation	1/2053	41/18722	0.991498350554489	0.999339302666251	TRMT1	1
GO:0050913	sensory perception of bitter taste	1/2053	41/18722	0.991498350554489	0.999339302666251	PLCB2	1
GO:0035278	miRNA mediated inhibition of translation	4/2053	90/18722	0.99167770134581	0.999339302666251	ZFP36/STAT3/AGO2/EIF4G1	4
GO:0040033	negative regulation of translation, ncRNA-mediated	4/2053	90/18722	0.99167770134581	0.999339302666251	ZFP36/STAT3/AGO2/EIF4G1	4
GO:0045974	regulation of translation, ncRNA-mediated	4/2053	91/18722	0.992366091209495	0.999428663403853	ZFP36/STAT3/AGO2/EIF4G1	4
GO:0021575	hindbrain morphogenesis	1/2053	42/18722	0.992432662760026	0.999428663403853	HSPA5	1
GO:0055090	acylglycerol homeostasis	1/2053	42/18722	0.992432662760026	0.999428663403853	IL18	1
GO:0070328	triglyceride homeostasis	1/2053	42/18722	0.992432662760026	0.999428663403853	IL18	1
GO:1905515	non-motile cilium assembly	2/2053	61/18722	0.992933299347493	0.999765027032213	KCNQ1/ATMIN	2
GO:0045494	photoreceptor cell maintenance	1/2053	43/18722	0.993264340669751	0.999930544298408	SLC2A1	1
GO:0032007	negative regulation of TOR signaling	1/2053	44/18722	0.994004653780999	1	DDIT4	1
GO:0043039	tRNA aminoacylation	1/2053	44/18722	0.994004653780999	1	IARS2	1
GO:0043038	amino acid activation	1/2053	45/18722	0.994663634709772	1	IARS2	1
GO:0046854	phosphatidylinositol phosphate biosynthetic process	2/2053	64/18722	0.994801419360676	1	SOCS3/IMPA2	2
GO:0032924	activin receptor signaling pathway	1/2053	46/18722	0.995250214885434	1	FKBP1A	1
GO:0006805	xenobiotic metabolic process	5/2053	111/18722	0.995307869002783	1	S100A12/GSTP1/SULT1A1/NUDT15/VKORC1	5
GO:0061512	protein localization to cilium	2/2053	65/18722	0.995309005938641	1	SNX10/CCDC88A	2
GO:0050909	sensory perception of taste	2/2053	66/18722	0.995767851710662	1	CD36/PLCB2	2
GO:0120254	olefinic compound metabolic process	8/2053	153/18722	0.995772474045808	1	GPX1/ALOX5/GSTP1/TBXAS1/HSD17B1/AKR1B1/ALDH1A1/MGLL	8
GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	2/2053	67/18722	0.996182536074472	1	CCR1/HRH2	2
GO:0015837	amine transport	4/2053	99/18722	0.99621348939512	1	AQP9/ITGB1/SYT7/RGS2	4
GO:0044458	motile cilium assembly	1/2053	48/18722	0.996237104399488	1	ATMIN	1
GO:0099504	synaptic vesicle cycle	10/2053	181/18722	0.996382665814743	1	ACTB/LRRK2/STX11/PRKCB/ITSN2/SYT7/RAP1A/CHRNA5/PICALM/AP2M1	10
GO:0008206	bile acid metabolic process	1/2053	49/18722	0.996650793200379	1	SLC27A2	1
GO:0007018	microtubule-based movement	26/2053	382/18722	0.997972460149462	1	APP/SOD1/CATSPER1/HSPB11/UBB/HSPA8/KPNB1/ACTR2/KIF23/SLIRP/KIF21A/KIF20B/CFAP20/KIF22/ARMCX3/ACTR3/ARHGAP21/DYNC1LI2/ING2/LRPPRC/KIF4A/DEFB1/PURA/KIF11/DYNLT1/KIFC1	26
GO:0099111	microtubule-based transport	10/2053	190/18722	0.998080764064779	1	APP/SOD1/HSPB11/UBB/HSPA8/ARMCX3/ARHGAP21/LRPPRC/KIF4A/PURA	10
GO:0051952	regulation of amine transport	3/2053	91/18722	0.998124151882923	1	ITGB1/SYT7/RGS2	3
GO:0050433	regulation of catecholamine secretion	1/2053	56/18722	0.998518164233082	1	SYT7	1
GO:0060294	cilium movement involved in cell motility	5/2053	125/18722	0.998573948795736	1	CATSPER1/SLIRP/CFAP20/ING2/DEFB1	5
GO:0030317	flagellated sperm motility	4/2053	110/18722	0.998594517207722	1	CATSPER1/SLIRP/ING2/DEFB1	4
GO:0097722	sperm motility	4/2053	110/18722	0.998594517207722	1	CATSPER1/SLIRP/ING2/DEFB1	4
GO:0008033	tRNA processing	5/2053	127/18722	0.998801693074249	1	POP7/TRMT1/POLR3K/TSEN34/DDX1	5
GO:0050432	catecholamine secretion	1/2053	58/18722	0.998826208920013	1	SYT7	1
GO:0060271	cilium assembly	21/2053	337/18722	0.999043086543356	1	FLNA/SNX10/GALNT11/LAMA5/NOTCH1/KCNQ1/CCDC88A/DYNLL2/ACTR2/AHI1/RAB3IP/CFAP20/YAP1/ACTR3/FNBP1L/VDAC3/ATMIN/RILPL2/CENPJ/CCP110/ODF2L	21
GO:0001510	RNA methylation	2/2053	83/18722	0.999282957674131	1	TRMT1/FBL	2
GO:0097194	execution phase of apoptosis	2/2053	85/18722	0.999419688400843	1	TOP2A/PLSCR1	2
GO:0001539	cilium or flagellum-dependent cell motility	5/2053	138/18722	0.999546736599206	1	CATSPER1/SLIRP/CFAP20/ING2/DEFB1	5
GO:0007224	smoothened signaling pathway	5/2053	138/18722	0.999546736599206	1	HSPB11/DLG5/GLI3/VCP/GPC3	5
GO:0060285	cilium-dependent cell motility	5/2053	138/18722	0.999546736599206	1	CATSPER1/SLIRP/CFAP20/ING2/DEFB1	5
GO:0007218	neuropeptide signaling pathway	3/2053	106/18722	0.999568196112473	1	SORL1/CYSLTR1/GPR84	3
GO:0044782	cilium organization	22/2053	368/18722	0.999692657154469	1	FLNA/SNX10/GALNT11/LAMA5/NOTCH1/KCNQ1/HSPB11/CCDC88A/DYNLL2/ACTR2/AHI1/RAB3IP/CFAP20/YAP1/ACTR3/FNBP1L/VDAC3/ATMIN/RILPL2/CENPJ/CCP110/ODF2L	22
GO:0007601	visual perception	10/2053	215/18722	0.999699301986922	1	TGFBI/EFEMP1/TIMP3/PPT1/TACSTD2/EPAS1/OAT/DNAJC19/BEST1/MYO7A	10
GO:0050953	sensory perception of light stimulus	10/2053	219/18722	0.999778997259824	1	TGFBI/EFEMP1/TIMP3/PPT1/TACSTD2/EPAS1/OAT/DNAJC19/BEST1/MYO7A	10
GO:0001578	microtubule bundle formation	3/2053	113/18722	0.999785212027554	1	PRC1/CLIP1/CHP1	3
GO:0006399	tRNA metabolic process	7/2053	179/18722	0.999823320909947	1	POP7/EXOSC8/TRMT1/IARS2/POLR3K/TSEN34/DDX1	7
GO:0009451	RNA modification	6/2053	167/18722	0.999864721500302	1	APOBEC3A/TRMT1/APOBEC3G/APOBEC3C/NHP2/FBL	6
GO:0009953	dorsal/ventral pattern formation	1/2053	84/18722	0.999943399196268	1	GLI3	1
GO:0006400	tRNA modification	1/2053	90/18722	0.999971901940125	1	TRMT1	1
GO:0003341	cilium movement	5/2053	175/18722	0.999985233830548	1	CATSPER1/SLIRP/CFAP20/ING2/DEFB1	5
GO:0007608	sensory perception of smell	1/2053	456/18722	1	1	PDE4A	1