ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0001667 ameboidal-type cell migration 24/244 475/18722 1.62390487549521e-08 5.33615142087727e-05 ITGB4/LRP5/NR2F2/NRP2/EPHB4/SEMA6A/ISL1/SEMA6D/KANK1/TACSTD2/BMP7/MET/ITGB1/FOLR1/LAMA5/MIA3/DPP4/GJA1/MACF1/ATP2B4/LGMN/PLPP3/AMOT/HYAL2 24 GO:0030198 extracellular matrix organization 18/244 301/18722 9.11808020417636e-08 8.69465428021885e-05 CCDC80/LAMC1/LRP1/ADAMTSL4/COL14A1/LAMB1/ADAMTS1/SPINT1/APP/CTSV/DAG1/ITGB1/SERPINH1/DPP4/MMP15/VWA1/FOXC1/CST3 18 GO:0043062 extracellular structure organization 18/244 302/18722 9.58461136591265e-08 8.69465428021885e-05 CCDC80/LAMC1/LRP1/ADAMTSL4/COL14A1/LAMB1/ADAMTS1/SPINT1/APP/CTSV/DAG1/ITGB1/SERPINH1/DPP4/MMP15/VWA1/FOXC1/CST3 18 GO:0045229 external encapsulating structure organization 18/244 304/18722 1.05838761779901e-07 8.69465428021885e-05 CCDC80/LAMC1/LRP1/ADAMTSL4/COL14A1/LAMB1/ADAMTS1/SPINT1/APP/CTSV/DAG1/ITGB1/SERPINH1/DPP4/MMP15/VWA1/FOXC1/CST3 18 GO:0031589 cell-substrate adhesion 19/244 363/18722 3.16110935409903e-07 0.000207748106751388 CCDC80/LAMC1/ITGB4/BCAM/EFNA5/LRP1/UTRN/LAMB1/KANK1/TACSTD2/ITGAV/DAG1/ITGB1/LAMA5/VCL/P4HB/MACF1/SLK/GCNT2 19 GO:0007411 axon guidance 14/244 227/18722 1.76672421562375e-06 0.000764305537435023 EFNA5/LRP1/NRP2/EPHB4/SEMA6A/ISL1/SEMA6D/PALLD/BMP7/APP/DAG1/LAMA5/DPYSL2/GLI3 14 GO:0048864 stem cell development 9/244 86/18722 1.79849762891261e-06 0.000764305537435023 NRP2/SEMA6A/ISL1/SEMA6D/BMP7/FOLR1/LAMA5/FOXC1/MSI2 9 GO:0097485 neuron projection guidance 14/244 228/18722 1.8607560254048e-06 0.000764305537435023 EFNA5/LRP1/NRP2/EPHB4/SEMA6A/ISL1/SEMA6D/PALLD/BMP7/APP/DAG1/LAMA5/DPYSL2/GLI3 14 GO:0042060 wound healing 19/244 422/18722 2.99210779778007e-06 0.00107983624568002 F5/DST/IL6ST/KANK1/CLDN4/DAG1/ITGB1/DCBLD2/VCL/MIA3/GJA1/MACF1/GLI3/PLPP3/GNAQ/HPS6/LMAN1/SERPINE2/TSKU 19 GO:0061564 axon development 20/244 467/18722 3.47986117912247e-06 0.00107983624568002 EFNA5/LRP1/NRP2/EPHB4/SEMA6A/ISL1/SEMA6D/PALLD/BMP7/APP/DAG1/ITGB1/FOLR1/LAMA5/VCL/DPYSL2/MACF1/GLI3/MTR/TSKU 20 GO:0035461 vitamin transmembrane transport 5/244 19/18722 3.61478962339631e-06 0.00107983624568002 LRP2/SLC19A3/FOLR1/SLC46A1/SLC19A1 5 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 17/244 355/18722 4.46839555518229e-06 0.00122359564952742 LRP2/FBN1/FBN2/JUN/LRP1/NCEH1/LATS2/BMP7/PEG10/FOLR1/HSPA5/ITGB8/FUT8/SPTBN1/TGFBR3/DDX5/GCNT2 17 GO:0003151 outflow tract morphogenesis 8/244 74/18722 5.3294796962021e-06 0.00126147248272506 LRP2/NRP2/ISL1/BMP7/GJA5/FOLR1/TGFBR3/FOXC1 8 GO:0061337 cardiac conduction 9/244 98/18722 5.37450236097105e-06 0.00126147248272506 ISL1/ATP2B1/CALM1/GJA5/AKAP9/DSC2/GJA1/ATP2B4/DSG2 9 GO:0007369 gastrulation 12/244 185/18722 5.84966745943494e-06 0.00128146715144688 ITGB4/LRP5/LAMB1/BMP7/ITGAV/DAG1/ITGB1/WLS/MMP15/GJA1/AMOT/FOXC1 12 GO:0030111 regulation of Wnt signaling pathway 16/244 328/18722 6.80314042770456e-06 0.00134065873041552 LGR5/LRP1/ISL1/KANK1/LATS2/APP/FOLR1/TLE4/WLS/MACF1/LGR4/GLI3/PLPP3/TBL1X/GNAQ/TSKU 16 GO:0001755 neural crest cell migration 7/244 55/18722 6.97987607260537e-06 0.00134065873041552 NRP2/SEMA6A/ISL1/SEMA6D/BMP7/FOLR1/LAMA5 7 GO:0048638 regulation of developmental growth 16/244 330/18722 7.34383966752263e-06 0.00134065873041552 LRP1/SEMA6A/SEMA6D/ADRB1/SLC6A4/LATS2/APP/JARID2/DPYSL2/GJA1/MACF1/WWC1/LGMN/TGFBR3/HOPX/FOXC1 16 GO:0007409 axonogenesis 18/244 418/18722 1.00853061562415e-05 0.00165237818244681 EFNA5/LRP1/NRP2/EPHB4/SEMA6A/ISL1/SEMA6D/PALLD/BMP7/APP/DAG1/ITGB1/LAMA5/VCL/DPYSL2/MACF1/GLI3/TSKU 18 GO:0014032 neural crest cell development 8/244 81/18722 1.05166952785193e-05 0.00165237818244681 NRP2/SEMA6A/ISL1/SEMA6D/BMP7/FOLR1/LAMA5/FOXC1 8 GO:0072001 renal system development 15/244 302/18722 1.06943910689602e-05 0.00165237818244681 LRP2/LGR5/FBN1/FRAS1/ADAMTS1/TACSTD2/BMP7/PBX1/LAMA5/ENPEP/IFT27/LGR4/GLI3/FOXC1/HYAL2 15 GO:0007229 integrin-mediated signaling pathway 9/244 107/18722 1.10627875878971e-05 0.00165237818244681 ITGB4/DST/ADAMTS1/ITGAV/ITGB1/LAMA5/ITGB8/FUT8/PLPP3 9 GO:0006835 dicarboxylic acid transport 8/244 84/18722 1.37838676962119e-05 0.00196929518477184 LRP2/SLC26A2/ITGB1/FOLR1/SLC46A1/GJA1/SLC19A1/SLC1A3 8 GO:0014031 mesenchymal cell development 8/244 86/18722 1.64055499206412e-05 0.00224619320996779 NRP2/SEMA6A/ISL1/SEMA6D/BMP7/FOLR1/LAMA5/FOXC1 8 GO:0048863 stem cell differentiation 12/244 206/18722 1.73591161746928e-05 0.00228168223000163 NRP2/SEMA6A/ISL1/SEMA6D/TACSTD2/BMP7/FOLR1/LAMA5/JARID2/PUM1/FOXC1/MSI2 12 GO:0098656 anion transmembrane transport 13/244 245/18722 2.09288716976185e-05 0.00264508739993748 LRP2/SLC26A2/TCAF1/SLC35D1/ITGB1/FOLR1/SLC46A1/SLC38A9/GABRE/GJA1/SLC12A9/SLC19A1/SLC1A3 13 GO:0098901 regulation of cardiac muscle cell action potential 5/244 27/18722 2.30472713736212e-05 0.00280493828643405 CALM1/GJA5/AKAP9/DSC2/DSG2 5 GO:0051180 vitamin transport 6/244 45/18722 2.45250700212334e-05 0.00281560317018338 LRP2/SLC19A3/FOLR1/SLC46A1/SLC52A3/SLC19A1 6 GO:0014033 neural crest cell differentiation 8/244 91/18722 2.48485976674735e-05 0.00281560317018338 NRP2/SEMA6A/ISL1/SEMA6D/BMP7/FOLR1/LAMA5/FOXC1 8 GO:0030902 hindbrain development 10/244 151/18722 2.95555431476631e-05 0.00305676523079098 NLGN4X/SLC6A4/BMP7/NAGLU/ITGB1/HSPA5/WLS/RERE/SERPINE2/FOXC1 10 GO:0048592 eye morphogenesis 10/244 151/18722 2.95555431476631e-05 0.00305676523079098 FBN1/FBN2/LRP5/TENM3/BMP7/NAGLU/TUG1/GLI3/EFEMP1/TSKU 10 GO:0001704 formation of primary germ layer 9/244 121/18722 2.97676468001556e-05 0.00305676523079098 ITGB4/LAMB1/BMP7/ITGAV/ITGB1/WLS/MMP15/GJA1/FOXC1 9 GO:0001822 kidney development 14/244 293/18722 3.23476083508998e-05 0.00322103760730475 LRP2/FBN1/FRAS1/ADAMTS1/TACSTD2/BMP7/PBX1/LAMA5/ENPEP/IFT27/LGR4/GLI3/FOXC1/HYAL2 14 GO:0007044 cell-substrate junction assembly 8/244 95/18722 3.39861701396301e-05 0.0032637750215876 LAMC1/ITGB4/EFNA5/DST/LRP1/VCL/MACF1/SLK 8 GO:0010810 regulation of cell-substrate adhesion 12/244 221/18722 3.47632762494114e-05 0.0032637750215876 CCDC80/EFNA5/LRP1/UTRN/KANK1/TACSTD2/DAG1/VCL/P4HB/MACF1/SLK/GCNT2 12 GO:0001655 urogenital system development 15/244 338/18722 3.97472346090672e-05 0.00362803924792763 LRP2/LGR5/FBN1/FRAS1/ADAMTS1/TACSTD2/BMP7/PBX1/LAMA5/ENPEP/IFT27/LGR4/GLI3/FOXC1/HYAL2 15 GO:0033627 cell adhesion mediated by integrin 7/244 72/18722 4.19886003751493e-05 0.00369566289802779 FBN1/ITGB4/ITGAV/ITGB1/ITGB8/DPP4/PLPP3 7 GO:0048880 sensory system development 16/244 381/18722 4.27374285225369e-05 0.00369566289802779 FBN1/FBN2/LRP5/ISL1/TENM3/ATP2B1/BMP7/NAGLU/TUG1/CPAMD8/PBX1/ATP2B4/GLI3/EFEMP1/FOXC1/TSKU 16 GO:0150115 cell-substrate junction organization 8/244 101/18722 5.28456704838084e-05 0.00438414797416409 LAMC1/ITGB4/EFNA5/DST/LRP1/VCL/MACF1/SLK 8 GO:0072337 modified amino acid transport 5/244 32/18722 5.45146640375795e-05 0.00438414797416409 LRP2/FOLR1/SLC46A1/GJA1/SLC19A1 5 GO:0001763 morphogenesis of a branching structure 11/244 196/18722 5.4701785435401e-05 0.00438414797416409 LRP5/TACSTD2/SPINT1/BMP7/MET/DAG1/PBX1/LAMA5/LGR4/RERE/GLI3 11 GO:0007179 transforming growth factor beta receptor signaling pathway 11/244 198/18722 5.9964217785676e-05 0.0046914861819936 FBN1/FBN2/JUN/LATS2/PEG10/FOLR1/HSPA5/ITGB8/FUT8/TGFBR3/GCNT2 11 GO:0021675 nerve development 7/244 77/18722 6.48657283379257e-05 0.00490515546801159 NRP2/ISL1/CTSV/DAG1/GLI3/SERPINE2/SLC1A3 7 GO:0048762 mesenchymal cell differentiation 12/244 236/18722 6.5680718378731e-05 0.00490515546801159 NRP2/SEMA6A/ISL1/SEMA6D/BMP7/DAG1/FOLR1/LAMA5/TGFBR3/DDX5/GCNT2/FOXC1 12 GO:0006766 vitamin metabolic process 8/244 106/18722 7.45811185866497e-05 0.00544607901501624 LRP2/SLC19A3/FOLR1/SLC46A1/SLC52A3/LGMN/MTR/SLC19A1 8 GO:0016055 Wnt signaling pathway 17/244 444/18722 7.76002269819363e-05 0.0054744021489812 LGR5/LRP5/LRP1/ISL1/KANK1/LATS2/APP/FOLR1/TLE4/WLS/MACF1/LGR4/GLI3/PLPP3/TBL1X/GNAQ/TSKU 17 GO:0003229 ventricular cardiac muscle tissue development 6/244 55/18722 7.83009437011919e-05 0.0054744021489812 LRP2/ISL1/DSG2/TGFBR3/HOPX/FOXC1 6 GO:0198738 cell-cell signaling by wnt 17/244 446/18722 8.19661182272842e-05 0.00561126384364283 LGR5/LRP5/LRP1/ISL1/KANK1/LATS2/APP/FOLR1/TLE4/WLS/MACF1/LGR4/GLI3/PLPP3/TBL1X/GNAQ/TSKU 17 GO:0034446 substrate adhesion-dependent cell spreading 8/244 108/18722 8.51363746133583e-05 0.0056251477216288 LAMC1/EFNA5/LAMB1/KANK1/TACSTD2/ITGAV/LAMA5/P4HB 8 GO:0008016 regulation of heart contraction 11/244 206/18722 8.55926311872916e-05 0.0056251477216288 ISL1/ADRB1/ATP2B1/CALM1/GJA5/AKAP9/DSC2/GJA1/ATP2B4/DSG2/HOPX 11 GO:0003014 renal system process 8/244 110/18722 9.69012061581434e-05 0.00624347771442469 CLDN4/GJA5/ATP6V1B1/GJA1/LGMN/MAGED2/MLLT6/HYAL2 8 GO:0051271 negative regulation of cellular component movement 15/244 367/18722 0.000100358136093336 0.0063418622154366 NR2F2/LRP1/TCAF1/SEMA6D/KANK1/TACSTD2/DAG1/VCL/MIA3/DPP4/GJA1/ATP2B4/CDH1/TGFBR3/HYAL2 15 GO:0071692 protein localization to extracellular region 15/244 368/18722 0.000103425846065187 0.00641240245604161 FBN1/FBN2/EFNA5/LRP5/LRP1/ISL1/KCNN4/ARL4D/ERP29/WLS/MIA3/DPP4/GJA1/MYH10/RAB11FIP1 15 GO:0048640 negative regulation of developmental growth 8/244 112/18722 0.000109981211343655 0.00654870175281446 SEMA6A/SEMA6D/ADRB1/SLC6A4/JARID2/GJA1/WWC1/LGMN 8 GO:0003161 cardiac conduction system development 5/244 37/18722 0.000111903428510404 0.00654870175281446 ISL1/GJA5/GJA1/DSG2/HOPX 5 GO:0001654 eye development 15/244 371/18722 0.000113125477806761 0.00654870175281446 FBN1/FBN2/LRP5/TENM3/ATP2B1/BMP7/NAGLU/TUG1/CPAMD8/PBX1/ATP2B4/GLI3/EFEMP1/FOXC1/TSKU 15 GO:0071560 cellular response to transforming growth factor beta stimulus 12/244 250/18722 0.000113595861202198 0.00654870175281446 FBN1/FBN2/JUN/LATS2/PEG10/FOLR1/HSPA5/ITGB8/FUT8/TGFBR3/GCNT2/HYAL2 12 GO:0006767 water-soluble vitamin metabolic process 6/244 59/18722 0.000116530991739464 0.00660208342854966 SLC19A3/FOLR1/SLC46A1/SLC52A3/MTR/SLC19A1 6 GO:0150063 visual system development 15/244 375/18722 0.000127286809545898 0.00708922807064101 FBN1/FBN2/LRP5/TENM3/ATP2B1/BMP7/NAGLU/TUG1/CPAMD8/PBX1/ATP2B4/GLI3/EFEMP1/FOXC1/TSKU 15 GO:0034329 cell junction assembly 16/244 420/18722 0.000133606464857126 0.00731718072534194 NLGN4X/LAMC1/ITGB4/EFNA5/DST/LRP1/PPP1R9A/POF1B/APP/CLDN4/GJA5/VCL/GJA1/MACF1/CDH1/SLK 16 GO:0034113 heterotypic cell-cell adhesion 6/244 61/18722 0.000140523066024593 0.00734050874065323 BMP7/ITGAV/ITGB1/DSC2/DSG2/GCNT2 6 GO:0071559 response to transforming growth factor beta 12/244 256/18722 0.000141902920429787 0.00734050874065323 FBN1/FBN2/JUN/LATS2/PEG10/FOLR1/HSPA5/ITGB8/FUT8/TGFBR3/GCNT2/HYAL2 12 GO:0061138 morphogenesis of a branching epithelium 10/244 182/18722 0.000141931387818318 0.00734050874065323 LRP5/TACSTD2/SPINT1/BMP7/MET/DAG1/PBX1/LAMA5/LGR4/GLI3 10 GO:0050878 regulation of body fluid levels 15/244 379/18722 0.000142967912173404 0.00734050874065323 F5/IL6ST/KCNN4/CLDN4/MET/GJA5/ATP6V1B1/VCL/GJA1/GNAQ/HPS6/LMAN1/SERPINE2/MLLT6/HYAL2 15 GO:0048608 reproductive structure development 16/244 424/18722 0.000148894908239162 0.00752721028421362 LRP2/NR2F2/ADAMTS1/SPINT1/BMP7/CTSV/HSPA5/ITGB8/GJA1/DHCR24/LGR4/GLI3/SF1/SERPINE2/FOXC1/KRT19 16 GO:0061458 reproductive system development 16/244 427/18722 0.000161342523836082 0.00801347803960806 LRP2/NR2F2/ADAMTS1/SPINT1/BMP7/CTSV/HSPA5/ITGB8/GJA1/DHCR24/LGR4/GLI3/SF1/SERPINE2/FOXC1/KRT19 16 GO:0014706 striated muscle tissue development 15/244 384/18722 0.000164912258008564 0.00801347803960806 LRP2/SVIL/NR2F2/ISL1/BMP7/GJA5/ITGB1/JARID2/GJA1/RCAN1/DSG2/TGFBR3/DDX5/HOPX/FOXC1 15 GO:0048754 branching morphogenesis of an epithelial tube 9/244 151/18722 0.000165856657230252 0.00801347803960806 LRP5/TACSTD2/BMP7/MET/DAG1/PBX1/LAMA5/LGR4/GLI3 9 GO:0022617 extracellular matrix disassembly 6/244 63/18722 0.000168268406796396 0.00801347803960806 LAMC1/LRP1/CTSV/DPP4/MMP15/CST3 6 GO:0048675 axon extension 8/244 120/18722 0.000177783508034963 0.00820937123249363 LRP1/NRP2/SEMA6A/SEMA6D/ITGB1/VCL/DPYSL2/MACF1 8 GO:0030336 negative regulation of cell migration 14/244 344/18722 0.000178531704118401 0.00820937123249363 NR2F2/LRP1/TCAF1/SEMA6D/KANK1/TACSTD2/DAG1/VCL/MIA3/DPP4/GJA1/ATP2B4/CDH1/HYAL2 14 GO:0060070 canonical Wnt signaling pathway 13/244 303/18722 0.000181554251727325 0.00820937123249363 LGR5/LRP5/ISL1/KANK1/LATS2/FOLR1/TLE4/WLS/LGR4/GLI3/PLPP3/TBL1X/GNAQ 13 GO:0003018 vascular process in circulatory system 12/244 263/18722 0.000182374954343285 0.00820937123249363 LRP2/LRP1/ADRB1/ATP2B1/SLC6A4/SOD3/GJA5/GJA1/ATP2B4/SLC19A1/FOXC1/SLC1A3 12 GO:0001657 ureteric bud development 7/244 91/18722 0.000187115198643063 0.00830892625325818 TACSTD2/BMP7/PBX1/LAMA5/LGR4/GLI3/FOXC1 7 GO:0072163 mesonephric epithelium development 7/244 92/18722 0.000200308341639028 0.00847559599250356 TACSTD2/BMP7/PBX1/LAMA5/LGR4/GLI3/FOXC1 7 GO:0072164 mesonephric tubule development 7/244 92/18722 0.000200308341639028 0.00847559599250356 TACSTD2/BMP7/PBX1/LAMA5/LGR4/GLI3/FOXC1 7 GO:0040013 negative regulation of locomotion 15/244 391/18722 0.000200521011737626 0.00847559599250356 NR2F2/LRP1/TCAF1/SEMA6A/SEMA6D/KANK1/TACSTD2/DAG1/VCL/MIA3/DPP4/GJA1/ATP2B4/CDH1/HYAL2 15 GO:0098657 import into cell 11/244 227/18722 0.000201185784362531 0.00847559599250356 LRP2/SLC39A10/SLC6A4/ITGB1/FOLR1/SLC46A1/SLC27A2/ATP2B4/SLC12A9/SLC19A1/SLC1A3 11 GO:0060993 kidney morphogenesis 7/244 93/18722 0.000214242391545705 0.00891139871669855 FRAS1/TACSTD2/BMP7/PBX1/LAMA5/LGR4/GLI3 7 GO:0007160 cell-matrix adhesion 11/244 233/18722 0.00025201717921845 0.0103363184447891 ITGB4/BCAM/EFNA5/LRP1/UTRN/ITGAV/DAG1/ITGB1/VCL/MACF1/SLK 11 GO:0035637 multicellular organismal signaling 9/244 160/18722 0.000255971167786781 0.0103363184447891 ISL1/ATP2B1/CALM1/GJA5/AKAP9/DSC2/GJA1/ATP2B4/DSG2 9 GO:0001823 mesonephros development 7/244 96/18722 0.00026079943836479 0.0103363184447891 TACSTD2/BMP7/PBX1/LAMA5/LGR4/GLI3/FOXC1 7 GO:0010631 epithelial cell migration 14/244 357/18722 0.000261081689262781 0.0103363184447891 NR2F2/NRP2/EPHB4/KANK1/TACSTD2/MET/ITGB1/MIA3/DPP4/MACF1/ATP2B4/LGMN/PLPP3/AMOT 14 GO:2000146 negative regulation of cell motility 14/244 359/18722 0.000276321453386664 0.0106131746707303 NR2F2/LRP1/TCAF1/SEMA6D/KANK1/TACSTD2/DAG1/VCL/MIA3/DPP4/GJA1/ATP2B4/CDH1/HYAL2 14 GO:0060537 muscle tissue development 15/244 403/18722 0.000277163114694219 0.0106131746707303 LRP2/SVIL/NR2F2/ISL1/BMP7/GJA5/ITGB1/JARID2/GJA1/RCAN1/DSG2/TGFBR3/DDX5/HOPX/FOXC1 15 GO:0045665 negative regulation of neuron differentiation 6/244 69/18722 0.000278202357155907 0.0106131746707303 ISL1/SLC6A4/BMP7/APP/PBX1/GLI3 6 GO:0048738 cardiac muscle tissue development 11/244 236/18722 0.00028125402780236 0.0106131746707303 LRP2/ISL1/BMP7/GJA5/ITGB1/JARID2/GJA1/DSG2/TGFBR3/HOPX/FOXC1 11 GO:0090132 epithelium migration 14/244 360/18722 0.00028422378911268 0.0106131746707303 NR2F2/NRP2/EPHB4/KANK1/TACSTD2/MET/ITGB1/MIA3/DPP4/MACF1/ATP2B4/LGMN/PLPP3/AMOT 14 GO:0035272 exocrine system development 5/244 45/18722 0.000288164615806899 0.0106394261521513 BMP7/DAG1/LAMA5/WLS/FOXC1 5 GO:0050919 negative chemotaxis 5/244 46/18722 0.000319904357952228 0.0116800635581224 NRP2/SEMA6A/SEMA6D/ITGAV/DPP4 5 GO:0090130 tissue migration 14/244 365/18722 0.000326714045761923 0.0117976082898206 NR2F2/NRP2/EPHB4/KANK1/TACSTD2/MET/ITGB1/MIA3/DPP4/MACF1/ATP2B4/LGMN/PLPP3/AMOT 14 GO:0034975 protein folding in endoplasmic reticulum 3/244 11/18722 0.000333940723512435 0.0118838360843865 HSPA5/P4HB/PDIA3 3 GO:0060047 heart contraction 11/244 241/18722 0.000336334983520371 0.0118838360843865 ISL1/ADRB1/ATP2B1/CALM1/GJA5/AKAP9/DSC2/GJA1/ATP2B4/DSG2/HOPX 11 GO:0001707 mesoderm formation 6/244 72/18722 0.0003510081255659 0.012270347878825 ITGB4/BMP7/ITGB1/WLS/GJA1/FOXC1 6 GO:0060562 epithelial tube morphogenesis 13/244 325/18722 0.000357452021764938 0.0123640773002062 LRP2/LGR5/LRP5/TACSTD2/SPINT1/BMP7/MET/DAG1/FOLR1/PBX1/LAMA5/LGR4/GLI3 13 GO:0051235 maintenance of location 13/244 326/18722 0.000368066173449557 0.0125985983953671 FBN1/FBN2/MCOLN3/CDS1/CALM1/ITGAV/AKAP9/DZIP1/P2RY6/HSPA5/GJA1/HTT/SREBF2 13 GO:0048332 mesoderm morphogenesis 6/244 74/18722 0.000407283145217062 0.0137972413936419 ITGB4/BMP7/ITGB1/WLS/GJA1/FOXC1 6 GO:0061333 renal tubule morphogenesis 6/244 75/18722 0.000437939776613048 0.0146843888362293 LGR5/TACSTD2/PBX1/LAMA5/LGR4/GLI3 6 GO:0045926 negative regulation of growth 11/244 249/18722 0.000443242544527999 0.014712070720394 SEMA6A/SEMA6D/ADRB1/SLC6A4/DCBLD2/JARID2/GJA1/WWC1/LGMN/SERPINE2/HYAL2 11 GO:0060485 mesenchyme development 12/244 291/18722 0.000457501851485318 0.0150335108398076 NRP2/SEMA6A/ISL1/SEMA6D/BMP7/DAG1/FOLR1/LAMA5/TGFBR3/DDX5/GCNT2/FOXC1 12 GO:0072028 nephron morphogenesis 6/244 76/18722 0.000470366934219904 0.0150952059631839 TACSTD2/BMP7/PBX1/LAMA5/LGR4/GLI3 6 GO:0086001 cardiac muscle cell action potential 6/244 76/18722 0.000470366934219904 0.0150952059631839 CALM1/GJA5/AKAP9/DSC2/GJA1/DSG2 6 GO:0003015 heart process 11/244 251/18722 0.000474019409227856 0.0150952059631839 ISL1/ADRB1/ATP2B1/CALM1/GJA5/AKAP9/DSC2/GJA1/ATP2B4/DSG2/HOPX 11 GO:0046620 regulation of organ growth 7/244 106/18722 0.00047775454052682 0.0150952059631839 SLC6A4/LATS2/JARID2/GJA1/WWC1/TGFBR3/FOXC1 7 GO:0060828 regulation of canonical Wnt signaling pathway 11/244 253/18722 0.000506566383700101 0.0158531155889384 LGR5/ISL1/KANK1/LATS2/FOLR1/TLE4/WLS/LGR4/GLI3/TBL1X/GNAQ 11 GO:0098739 import across plasma membrane 9/244 177/18722 0.000536818445156298 0.0166413717998452 LRP2/SLC39A10/ITGB1/FOLR1/SLC46A1/ATP2B4/SLC12A9/SLC19A1/SLC1A3 9 GO:0072006 nephron development 8/244 142/18722 0.000555737190089125 0.0167021239469131 TACSTD2/BMP7/PBX1/LAMA5/ENPEP/LGR4/GLI3/FOXC1 8 GO:0090596 sensory organ morphogenesis 11/244 256/18722 0.000558879578149132 0.0167021239469131 FBN1/FBN2/LRP5/TENM3/BMP7/NAGLU/ATP6V1B1/TUG1/GLI3/EFEMP1/TSKU 11 GO:1903522 regulation of blood circulation 11/244 256/18722 0.000558879578149132 0.0167021239469131 ISL1/ADRB1/ATP2B1/CALM1/GJA5/AKAP9/DSC2/GJA1/ATP2B4/DSG2/HOPX 11 GO:0035265 organ growth 9/244 178/18722 0.000559110386502142 0.0167021239469131 NLGN4X/SLC6A4/LATS2/JARID2/GJA1/WWC1/TGFBR3/FOXC1/TSKU 9 GO:0098814 spontaneous synaptic transmission 3/244 13/18722 0.000567763923119454 0.0167021239469131 PPP1R9A/APP/ITGB1 3 GO:0031103 axon regeneration 5/244 52/18722 0.000569275070619072 0.0167021239469131 LRP1/ISL1/DAG1/FOLR1/MTR 5 GO:0051222 positive regulation of protein transport 12/244 303/18722 0.000654128506630372 0.0190218254228974 LRP1/TCAF1/ISL1/KCNN4/WLS/GJA1/HUWE1/GLI3/CDH1/MYH10/SREBF2/HYAL2 12 GO:0007190 activation of adenylate cyclase activity 4/244 31/18722 0.000671602522749095 0.0193477077191751 LGR5/ADRB1/CALM1/LGR4 4 GO:0010466 negative regulation of peptidase activity 11/244 262/18722 0.000677110890963217 0.0193477077191751 LRP1/APLP2/SPINT1/APP/ITIH5/GAPDH/CPAMD8/SERPINH1/DHCR24/SERPINE2/CST3 11 GO:0043588 skin development 11/244 263/18722 0.000698706507244247 0.0197622252034161 LGR5/ITGB4/FRAS1/PALLD/CLDN4/MET/LAMA5/DHCR24/LGR4/ASAH1/FOXC1 11 GO:0010771 negative regulation of cell morphogenesis involved in differentiation 3/244 14/18722 0.000715674010714095 0.0197622252034161 EFNA5/KANK1/TACSTD2 3 GO:0046655 folic acid metabolic process 3/244 14/18722 0.000715674010714095 0.0197622252034161 FOLR1/SLC46A1/SLC19A1 3 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading 3/244 14/18722 0.000715674010714095 0.0197622252034161 EFNA5/KANK1/TACSTD2 3 GO:0045861 negative regulation of proteolysis 13/244 351/18722 0.000735585461123131 0.0200483656434917 LRP1/APLP2/SPINT1/APP/ITIH5/GAPDH/CPAMD8/SERPINH1/DHCR24/USP25/SERPINE2/SVIP/CST3 13 GO:0098900 regulation of action potential 5/244 55/18722 0.000738238661857119 0.0200483656434917 CALM1/GJA5/AKAP9/DSC2/DSG2 5 GO:0015711 organic anion transport 13/244 354/18722 0.000795511359297905 0.0214266420217452 LRP2/SLC26A2/SLC35D1/ITGB1/FOLR1/SLC22A11/SLC46A1/SLC38A9/GJA1/SLC52A3/SLC19A1/PLEKHA8/SLC1A3 13 GO:0001658 branching involved in ureteric bud morphogenesis 5/244 56/18722 0.000802110064732157 0.0214287290464217 TACSTD2/PBX1/LAMA5/LGR4/GLI3 5 GO:0050708 regulation of protein secretion 11/244 268/18722 0.000815472834430054 0.0216100301123964 EFNA5/LRP5/LRP1/ISL1/KCNN4/ERP29/WLS/DPP4/GJA1/MYH10/RAB11FIP1 11 GO:0042558 pteridine-containing compound metabolic process 4/244 33/18722 0.00085578374820975 0.0223182967985495 FOLR1/SLC46A1/MTR/SLC19A1 4 GO:0048048 embryonic eye morphogenesis 4/244 33/18722 0.00085578374820975 0.0223182967985495 FBN1/FBN2/BMP7/EFEMP1 4 GO:0048569 post-embryonic animal organ development 3/244 15/18722 0.000886012806178347 0.0225692874504035 FBN1/LDHA/EFEMP1 3 GO:0086069 bundle of His cell to Purkinje myocyte communication 3/244 15/18722 0.000886012806178347 0.0225692874504035 GJA5/DSC2/DSG2 3 GO:1901660 calcium ion export 3/244 15/18722 0.000886012806178347 0.0225692874504035 ATP2B1/CALM1/ATP2B4 3 GO:0009306 protein secretion 13/244 359/18722 0.000904505829736543 0.0228631242808791 EFNA5/LRP5/LRP1/ISL1/KCNN4/ARL4D/ERP29/WLS/MIA3/DPP4/GJA1/MYH10/RAB11FIP1 13 GO:0035592 establishment of protein localization to extracellular region 13/244 360/18722 0.000927744061806025 0.0231600799414031 EFNA5/LRP5/LRP1/ISL1/KCNN4/ARL4D/ERP29/WLS/MIA3/DPP4/GJA1/MYH10/RAB11FIP1 13 GO:0010959 regulation of metal ion transport 14/244 406/18722 0.000930350137633967 0.0231600799414031 UTRN/ATP2B1/KCNN4/CALM1/AHNAK/AKAP9/ITGB1/P2RY6/GJA1/ATP2B4/HTT/STIM1/SERPINE2/MLLT6 14 GO:0086065 cell communication involved in cardiac conduction 5/244 58/18722 0.000942107509183445 0.0232764306404271 CALM1/GJA5/DSC2/GJA1/DSG2 5 GO:0086004 regulation of cardiac muscle cell contraction 4/244 34/18722 0.000960055690480806 0.023542858200895 GJA5/AKAP9/DSC2/DSG2 4 GO:0001503 ossification 14/244 408/18722 0.000975149815711994 0.0237358688476268 FBN2/SLC26A2/LRP5/IL6ST/ATP2B1/RRBP1/BMP7/ATP6V1B1/PBX1/LGR4/GLI3/DDX5/RDH14/FOXC1 14 GO:0043270 positive regulation of ion transport 11/244 275/18722 0.00100576951953568 0.0243011664793694 TCAF1/ATP2B1/SLC6A4/KCNN4/CALM1/AKAP9/ITGB1/P2RY6/HTT/STIM1/MLLT6 11 GO:1904951 positive regulation of establishment of protein localization 12/244 319/18722 0.00102251521848757 0.0243919913636968 LRP1/TCAF1/ISL1/KCNN4/WLS/GJA1/HUWE1/GLI3/CDH1/MYH10/SREBF2/HYAL2 12 GO:0010232 vascular transport 6/244 88/18722 0.00102437456122646 0.0243919913636968 LRP2/LRP1/GJA1/ATP2B4/SLC19A1/SLC1A3 6 GO:0003206 cardiac chamber morphogenesis 7/244 121/18722 0.00105013477256641 0.0248254882205268 LRP2/NRP2/ISL1/ADAMTS1/BMP7/TGFBR3/FOXC1 7 GO:0035633 maintenance of blood-brain barrier 4/244 35/18722 0.0010729497658484 0.0249927029514891 LAMC1/ITGB1/VCL/GJA1 4 GO:0010649 regulation of cell communication by electrical coupling 3/244 16/18722 0.00108002550794627 0.0249927029514891 CALM1/GJA5/GJA1 3 GO:0033631 cell-cell adhesion mediated by integrin 3/244 16/18722 0.00108002550794627 0.0249927029514891 ITGB1/DPP4/PLPP3 3 GO:0022898 regulation of transmembrane transporter activity 11/244 278/18722 0.00109786575426596 0.0250900103444134 TCAF1/UTRN/APP/CALM1/AHNAK/AKAP9/ITGB1/P2RY6/GJA1/HTT/STIM1 11 GO:0031102 neuron projection regeneration 5/244 60/18722 0.00109950136627983 0.0250900103444134 LRP1/ISL1/DAG1/FOLR1/MTR 5 GO:0043010 camera-type eye development 12/244 322/18722 0.0011078988974023 0.0251072812197515 FBN1/FBN2/LRP5/TENM3/ATP2B1/BMP7/NAGLU/ATP2B4/GLI3/EFEMP1/FOXC1/TSKU 12 GO:0043542 endothelial cell migration 11/244 279/18722 0.00113006845479051 0.0254342804276822 NR2F2/NRP2/EPHB4/MET/ITGB1/MIA3/DPP4/ATP2B4/LGMN/PLPP3/AMOT 11 GO:0034109 homotypic cell-cell adhesion 6/244 90/18722 0.00115179905719025 0.0255730520400484 IL6ST/DSC2/VCL/DSG2/PLPP3/SERPINE2 6 GO:0042475 odontogenesis of dentin-containing tooth 6/244 90/18722 0.00115179905719025 0.0255730520400484 BMP7/ANKRD11/LAMA5/GLI3/STIM1/FOXC1 6 GO:0031099 regeneration 9/244 198/18722 0.00119044520076729 0.026253710937727 LRP1/ISL1/DAG1/FOLR1/CPQ/GLI3/MTR/TGFBR3/HOPX 9 GO:0003205 cardiac chamber development 8/244 161/18722 0.00125939326919076 0.0275891085504055 LRP2/NRP2/ISL1/ADAMTS1/BMP7/GJA5/TGFBR3/FOXC1 8 GO:0060675 ureteric bud morphogenesis 5/244 62/18722 0.0012755825580331 0.0277154395125691 TACSTD2/PBX1/LAMA5/LGR4/GLI3 5 GO:0010715 regulation of extracellular matrix disassembly 3/244 17/18722 0.00129889765214109 0.0277154395125691 LRP1/DPP4/CST3 3 GO:0042953 lipoprotein transport 3/244 17/18722 0.00129889765214109 0.0277154395125691 LRP1/UNC119B/MIA3 3 GO:0070293 renal absorption 3/244 17/18722 0.00129889765214109 0.0277154395125691 CLDN4/MAGED2/HYAL2 3 GO:0072171 mesonephric tubule morphogenesis 5/244 63/18722 0.00137104067451902 0.0290660622998032 TACSTD2/PBX1/LAMA5/LGR4/GLI3 5 GO:0030048 actin filament-based movement 7/244 127/18722 0.00139172895955496 0.0293155215454973 GJA5/AKAP9/DSC2/SYNE2/GJA1/DSG2/MYH10 7 GO:0061326 renal tubule development 6/244 94/18722 0.00144276722392063 0.0300954766794193 LGR5/TACSTD2/PBX1/LAMA5/LGR4/GLI3 6 GO:0001952 regulation of cell-matrix adhesion 7/244 128/18722 0.00145623274255255 0.0300954766794193 EFNA5/LRP1/UTRN/DAG1/VCL/MACF1/SLK 7 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 7/244 128/18722 0.00145623274255255 0.0300954766794193 FBN1/FBN2/LATS2/PEG10/FOLR1/HSPA5/TGFBR3 7 GO:0048568 embryonic organ development 14/244 427/18722 0.00149911088027769 0.0306172523495971 FBN1/FBN2/NR2F2/SPINT1/BMP7/NAGLU/ATP6V1B1/FOLR1/PBX1/GLI3/EFEMP1/TEAD1/FOXC1/KRT19 14 GO:0003007 heart morphogenesis 10/244 246/18722 0.00150011492035457 0.0306172523495971 LRP2/NRP2/EPHB4/ISL1/ADAMTS1/BMP7/GJA5/FOLR1/TGFBR3/FOXC1 10 GO:0044872 lipoprotein localization 3/244 18/18722 0.00154375674363899 0.0313134855530724 LRP1/UNC119B/MIA3 3 GO:0048645 animal organ formation 5/244 65/18722 0.0015776225814243 0.0314649595777535 LRP2/ISL1/BMP7/FOLR1/GLI3 5 GO:0034767 positive regulation of ion transmembrane transport 8/244 167/18722 0.00158948251602378 0.0314649595777535 TCAF1/KCNN4/CALM1/AKAP9/ITGB1/P2RY6/HTT/STIM1 8 GO:0042476 odontogenesis 7/244 130/18722 0.00159222573453895 0.0314649595777535 LAMB1/BMP7/ANKRD11/LAMA5/GLI3/STIM1/FOXC1 7 GO:0046621 negative regulation of organ growth 4/244 39/18722 0.00161825263805245 0.0314649595777535 SLC6A4/JARID2/GJA1/WWC1 4 GO:0086091 regulation of heart rate by cardiac conduction 4/244 39/18722 0.00161825263805245 0.0314649595777535 ISL1/AKAP9/DSC2/DSG2 4 GO:1901021 positive regulation of calcium ion transmembrane transporter activity 4/244 39/18722 0.00161825263805245 0.0314649595777535 CALM1/P2RY6/HTT/STIM1 4 GO:1903115 regulation of actin filament-based movement 4/244 39/18722 0.00161825263805245 0.0314649595777535 GJA5/AKAP9/DSC2/DSG2 4 GO:0046683 response to organophosphorus 7/244 131/18722 0.00166382809339654 0.031716132797626 JUN/SLC6A4/APP/LDHA/AKAP9/P2RY6/HSPA5 7 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 7/244 131/18722 0.00166382809339654 0.031716132797626 LRP2/FBN1/FBN2/LRP1/PEG10/HSPA5/TGFBR3 7 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 7/244 131/18722 0.00166382809339654 0.031716132797626 FBN1/FBN2/LATS2/PEG10/FOLR1/HSPA5/TGFBR3 7 GO:0014015 positive regulation of gliogenesis 5/244 66/18722 0.00168908193535744 0.031716132797626 LRP2/IL6ST/SPINT1/DAG1/SERPINE2 5 GO:0051893 regulation of focal adhesion assembly 5/244 66/18722 0.00168908193535744 0.031716132797626 EFNA5/LRP1/VCL/MACF1/SLK 5 GO:0090109 regulation of cell-substrate junction assembly 5/244 66/18722 0.00168908193535744 0.031716132797626 EFNA5/LRP1/VCL/MACF1/SLK 5 GO:0042391 regulation of membrane potential 14/244 434/18722 0.00174369779156932 0.0325556303585045 NLGN4X/JUN/PPP1R9A/ADRB1/KCNN4/APP/CALM1/GJA5/AKAP9/DSC2/GABRE/GJA1/DSG2/GNAQ 14 GO:0035329 hippo signaling 4/244 40/18722 0.00177987670477913 0.0327214456073387 LATS2/WWC1/TEAD1/AMOT 4 GO:0071526 semaphorin-plexin signaling pathway 4/244 40/18722 0.00177987670477913 0.0327214456073387 NRP2/SEMA6A/SEMA6D/MET 4 GO:0010951 negative regulation of endopeptidase activity 10/244 252/18722 0.00179241028889865 0.0327214456073387 APLP2/SPINT1/APP/ITIH5/GAPDH/CPAMD8/SERPINH1/DHCR24/SERPINE2/CST3 10 GO:0090257 regulation of muscle system process 10/244 252/18722 0.00179241028889865 0.0327214456073387 IL6ST/ATP2B1/CALM1/GJA5/AKAP9/DAG1/JARID2/DSC2/ATP2B4/DSG2 10 GO:0006491 N-glycan processing 3/244 19/18722 0.00181567385132272 0.0328489400017684 MAN2A2/FUT8/GANAB 3 GO:0048732 gland development 14/244 436/18722 0.00181938742553921 0.0328489400017684 LRP5/ISL1/BMP7/MET/DAG1/PBX1/LAMA5/JARID2/WLS/GLI3/CDH1/TGFBR3/SERPINE2/FOXC1 14 GO:0021549 cerebellum development 6/244 99/18722 0.00188160312568625 0.0331900349049529 NLGN4X/NAGLU/HSPA5/RERE/SERPINE2/FOXC1 6 GO:0001508 action potential 7/244 134/18722 0.00189374955804381 0.0331900349049529 CALM1/GJA5/AKAP9/DSC2/GJA1/DSG2/GNAQ 7 GO:0048511 rhythmic process 11/244 298/18722 0.00190610447399891 0.0331900349049529 JUN/ADRB1/ADAMTS1/SLC6A4/CLDN4/NAGLU/HSPA5/HUWE1/LGR4/GNAQ/DDX5 11 GO:0007219 Notch signaling pathway 8/244 172/18722 0.00191393926459648 0.0331900349049529 IL6ST/GALNT11/BMP7/APP/AAK1/SREBF2/FOXC1/KRT19 8 GO:0048736 appendage development 8/244 172/18722 0.00191393926459648 0.0331900349049529 FBN2/ITGB4/LRP5/NR2F2/FRAS1/BMP7/PBX1/GLI3 8 GO:0060173 limb development 8/244 172/18722 0.00191393926459648 0.0331900349049529 FBN2/ITGB4/LRP5/NR2F2/FRAS1/BMP7/PBX1/GLI3 8 GO:1990138 neuron projection extension 8/244 172/18722 0.00191393926459648 0.0331900349049529 LRP1/NRP2/SEMA6A/SEMA6D/ITGB1/VCL/DPYSL2/MACF1 8 GO:0010812 negative regulation of cell-substrate adhesion 5/244 68/18722 0.00192918340439623 0.0331900349049529 EFNA5/LRP1/KANK1/TACSTD2/GCNT2 5 GO:0060411 cardiac septum morphogenesis 5/244 68/18722 0.00192918340439623 0.0331900349049529 LRP2/NRP2/ISL1/BMP7/TGFBR3 5 GO:0060840 artery development 6/244 100/18722 0.00198031037974006 0.0338921870199263 LRP2/LRP1/GJA5/FOLR1/GLI3/FOXC1 6 GO:0034976 response to endoplasmic reticulum stress 10/244 256/18722 0.00201169886454627 0.0340744457159745 JUN/TBL2/HSPA5/ERP29/P4HB/TMTC3/USP25/SVIP/DNAJB14/PDIA3 10 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 10/244 256/18722 0.00201169886454627 0.0340744457159745 LRP2/FBN1/FBN2/LRP1/LATS2/BMP7/PEG10/FOLR1/HSPA5/TGFBR3 10 GO:0045669 positive regulation of osteoblast differentiation 5/244 69/18722 0.00205816629871188 0.0343797934169884 FBN2/LRP5/IL6ST/BMP7/GLI3 5 GO:0072073 kidney epithelium development 7/244 136/18722 0.00206021268509074 0.0343797934169884 TACSTD2/BMP7/PBX1/LAMA5/LGR4/GLI3/FOXC1 7 GO:0042886 amide transport 11/244 301/18722 0.00206111360412255 0.0343797934169884 LRP2/EFNA5/LRP5/LRP1/ISL1/FOLR1/SLC46A1/DPP4/GJA1/SLC19A1/PLEKHA8 11 GO:0030574 collagen catabolic process 4/244 42/18722 0.00213607107777394 0.0352720078470612 CTSL/ITGB1/MMP15/CST3 4 GO:0045687 positive regulation of glial cell differentiation 4/244 42/18722 0.00213607107777394 0.0352720078470612 IL6ST/SPINT1/DAG1/SERPINE2 4 GO:0032970 regulation of actin filament-based process 13/244 396/18722 0.00216795138916995 0.0356194413240623 SVIL/EFNA5/LRP1/PPP1R9A/KANK1/TACSTD2/IQGAP2/MET/GJA5/AKAP9/DSC2/SPTBN1/DSG2 13 GO:0002027 regulation of heart rate 6/244 103/18722 0.00230001958238725 0.0374151700382401 ISL1/ADRB1/CALM1/AKAP9/DSC2/DSG2 6 GO:0003279 cardiac septum development 6/244 103/18722 0.00230001958238725 0.0374151700382401 LRP2/NRP2/ISL1/BMP7/GJA5/TGFBR3 6 GO:0061383 trabecula morphogenesis 4/244 43/18722 0.0023313710956458 0.0374259873850372 FBN2/ADAMTS1/BMP7/TGFBR3 4 GO:0072078 nephron tubule morphogenesis 5/244 71/18722 0.00233485313875004 0.0374259873850372 TACSTD2/PBX1/LAMA5/LGR4/GLI3 5 GO:0150116 regulation of cell-substrate junction organization 5/244 71/18722 0.00233485313875004 0.0374259873850372 EFNA5/LRP1/VCL/MACF1/SLK 5 GO:0032963 collagen metabolic process 6/244 104/18722 0.00241477366270712 0.0385104443395985 P3H2/CTSL/ITGB1/SERPINH1/MMP15/CST3 6 GO:0060445 branching involved in salivary gland morphogenesis 3/244 21/18722 0.00244469353721626 0.0385104443395985 BMP7/DAG1/LAMA5 3 GO:0044706 multi-multicellular organism process 9/244 220/18722 0.00244938614332809 0.0385104443395985 ITGB4/NR2F2/SLC6A4/CLDN4/CTSV/GJA1/SLC19A1/MAGED2/SERPINE2 9 GO:0048705 skeletal system morphogenesis 9/244 220/18722 0.00244938614332809 0.0385104443395985 FBN2/LRP5/BMP7/ANKRD11/SERPINH1/GLI3/FOXC1/HYAL2/TSKU 9 GO:1903036 positive regulation of response to wounding 5/244 72/18722 0.00248290127406229 0.0388514932693746 LRP1/KANK1/CLDN4/ITGB1/PLPP3 5 GO:0035296 regulation of tube diameter 7/244 141/18722 0.00252601470956446 0.0391532279982491 ADRB1/ATP2B1/SLC6A4/SOD3/GJA5/GJA1/FOXC1 7 GO:0097746 blood vessel diameter maintenance 7/244 141/18722 0.00252601470956446 0.0391532279982491 ADRB1/ATP2B1/SLC6A4/SOD3/GJA5/GJA1/FOXC1 7 GO:0032409 regulation of transporter activity 11/244 310/18722 0.00258871677560552 0.0399367292236607 TCAF1/UTRN/APP/CALM1/AHNAK/AKAP9/ITGB1/P2RY6/GJA1/HTT/STIM1 11 GO:0035150 regulation of tube size 7/244 142/18722 0.00262817724761132 0.0401264608377701 ADRB1/ATP2B1/SLC6A4/SOD3/GJA5/GJA1/FOXC1 7 GO:0072088 nephron epithelium morphogenesis 5/244 73/18722 0.00263764928209322 0.0401264608377701 TACSTD2/PBX1/LAMA5/LGR4/GLI3 5 GO:0086003 cardiac muscle cell contraction 5/244 73/18722 0.00263764928209322 0.0401264608377701 GJA5/AKAP9/DSC2/GJA1/DSG2 5 GO:0032412 regulation of ion transmembrane transporter activity 10/244 267/18722 0.00272825654972798 0.0413135991815952 TCAF1/UTRN/APP/CALM1/AHNAK/AKAP9/ITGB1/P2RY6/HTT/STIM1 10 GO:1904646 cellular response to amyloid-beta 4/244 45/18722 0.0027581777993415 0.0415751020579641 LRP1/APP/GJA1/LGMN 4 GO:0048844 artery morphogenesis 5/244 74/18722 0.00279927001664947 0.0416871467542094 LRP2/LRP1/GJA5/FOLR1/FOXC1 5 GO:0035024 negative regulation of Rho protein signal transduction 3/244 22/18722 0.00280366994299461 0.0416871467542094 KANK1/MET/ITGB1 3 GO:0060343 trabecula formation 3/244 22/18722 0.00280366994299461 0.0416871467542094 FBN2/ADAMTS1/TGFBR3 3 GO:0001890 placenta development 7/244 144/18722 0.00284200526679382 0.0417592885963935 NR2F2/SPINT1/BMP7/CTSV/ITGB8/GJA1/KRT19 7 GO:0046718 viral entry into host cell 7/244 144/18722 0.00284200526679382 0.0417592885963935 CTSL/ITGAV/DAG1/ITGB1/P4HB/DPP4/HYAL2 7 GO:0050769 positive regulation of neurogenesis 9/244 225/18722 0.00284664657504326 0.0417592885963935 LRP2/LRP1/IL6ST/SPINT1/DAG1/MACF1/CUX1/GLI3/SERPINE2 9 GO:0022037 metencephalon development 6/244 108/18722 0.00291732209318923 0.0426058684365325 NLGN4X/NAGLU/HSPA5/RERE/SERPINE2/FOXC1 6 GO:0055010 ventricular cardiac muscle tissue morphogenesis 4/244 46/18722 0.00299039431756905 0.0434798041041234 LRP2/ISL1/TGFBR3/FOXC1 4 GO:0052547 regulation of peptidase activity 14/244 461/18722 0.00301955115674288 0.0436371879151986 LRP1/APLP2/SPINT1/APP/ITIH5/CLDN4/GAPDH/CPAMD8/SERPINH1/PCOLCE2/DHCR24/LGMN/SERPINE2/CST3 14 GO:0006821 chloride transport 6/244 109/18722 0.00305433755949351 0.0436371879151986 SLC26A2/CLDN4/P2RY6/GABRE/SLC12A9/SLC1A3 6 GO:0032414 positive regulation of ion transmembrane transporter activity 6/244 109/18722 0.00305433755949351 0.0436371879151986 TCAF1/CALM1/AKAP9/P2RY6/HTT/STIM1 6 GO:0072009 nephron epithelium development 6/244 109/18722 0.00305433755949351 0.0436371879151986 TACSTD2/PBX1/LAMA5/LGR4/GLI3/FOXC1 6 GO:0050767 regulation of neurogenesis 12/244 364/18722 0.00306868429608166 0.0436523662204517 LRP2/LRP1/SEMA6A/IL6ST/SEMA6D/SPINT1/BMP7/DAG1/MACF1/CUX1/GLI3/SERPINE2 12 GO:0046942 carboxylic acid transport 10/244 273/18722 0.00319763769296969 0.0451265202913126 LRP2/SLC26A2/SLC35D1/ITGB1/FOLR1/SLC46A1/SLC38A9/GJA1/SLC19A1/SLC1A3 10 GO:0001649 osteoblast differentiation 9/244 229/18722 0.00319978065364451 0.0451265202913126 FBN2/LRP5/IL6ST/RRBP1/BMP7/LGR4/GLI3/DDX5/RDH14 9 GO:0008202 steroid metabolic process 11/244 319/18722 0.00322062556972141 0.0452263915474554 LRP2/LRP5/APP/PBX1/SLC27A2/DHCR24/ASAH1/LGMN/SF1/SREBF2/TSKU 11 GO:0014911 positive regulation of smooth muscle cell migration 4/244 47/18722 0.00323561964292379 0.0452436006240323 LRP1/SEMA6D/ADAMTS1/P2RY6 4 GO:0014074 response to purine-containing compound 7/244 148/18722 0.00330946093222223 0.0460800365393316 JUN/SLC6A4/APP/LDHA/AKAP9/P2RY6/HSPA5 7 GO:0055117 regulation of cardiac muscle contraction 5/244 77/18722 0.00332709851531077 0.0461301507228321 CALM1/GJA5/AKAP9/DSC2/DSG2 5 GO:1905039 carboxylic acid transmembrane transport 7/244 149/18722 0.00343499333802441 0.047309142633895 LRP2/ITGB1/FOLR1/SLC46A1/SLC38A9/SLC19A1/SLC1A3 7 GO:0007548 sex differentiation 10/244 276/18722 0.00345532386857419 0.047309142633895 LRP2/NR2F2/ADAMTS1/CTSV/PBX1/HSPA5/DHCR24/LGR4/SF1/FOXC1 10 GO:1903829 positive regulation of cellular protein localization 10/244 276/18722 0.00345532386857419 0.047309142633895 LRP1/TCAF1/ITGB1/ATP2B4/HUWE1/GLI3/SPTBN1/CDH1/SREBF2/HYAL2 10 GO:1903053 regulation of extracellular matrix organization 4/244 48/18722 0.0034941985123737 0.04764288926 LRP1/DAG1/DPP4/CST3 4 GO:1903825 organic acid transmembrane transport 7/244 150/18722 0.00356412377615779 0.0483954988779111 LRP2/ITGB1/FOLR1/SLC46A1/SLC38A9/SLC19A1/SLC1A3 7 GO:0003148 outflow tract septum morphogenesis 3/244 24/18722 0.00361486023329136 0.0486820931417844 LRP2/NRP2/ISL1 3 GO:0060561 apoptotic process involved in morphogenesis 3/244 24/18722 0.00361486023329136 0.0486820931417844 LRP5/BMP7/FOXC1 3 GO:0048588 developmental cell growth 9/244 234/18722 0.00368879792210276 0.0491824817653578 LRP1/NRP2/SEMA6A/SEMA6D/APP/ITGB1/VCL/DPYSL2/MACF1 9 GO:0060560 developmental growth involved in morphogenesis 9/244 234/18722 0.00368879792210276 0.0491824817653578 LRP1/NRP2/SEMA6A/SEMA6D/APP/ITGB1/VCL/DPYSL2/MACF1 9 GO:0044409 entry into host 7/244 151/18722 0.00369691813634917 0.0491824817653578 CTSL/ITGAV/DAG1/ITGB1/P4HB/DPP4/HYAL2 7 GO:0021695 cerebellar cortex development 4/244 49/18722 0.00376647114123749 0.0495064966804256 NAGLU/HSPA5/RERE/SERPINE2 4 GO:0060964 regulation of gene silencing by miRNA 4/244 49/18722 0.00376647114123749 0.0495064966804256 KCNQ1OT1/TNRC6B/PUM1/DDX5 4 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 4/244 49/18722 0.00376647114123749 0.0495064966804256 JUN/ADAMTS1/P2RY6/GJA1 4 GO:0007517 muscle organ development 11/244 327/18722 0.00388135477693933 0.0508132740917237 LRP2/SVIL/NR2F2/UTRN/ISL1/DAG1/LAMA5/RCAN1/TGFBR3/DDX5/FOXC1 11 GO:1901264 carbohydrate derivative transport 5/244 80/18722 0.00392300619588183 0.0511547553955067 SLC35D1/GJA1/SLC35A4/SLC19A1/PLEKHA8 5 GO:0086064 cell communication by electrical coupling involved in cardiac conduction 3/244 25/18722 0.00406864976419486 0.0528442020756692 CALM1/GJA5/GJA1 3 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 5/244 81/18722 0.00413757518079097 0.0530890936869414 FBN1/FBN2/PEG10/HSPA5/TGFBR3 5 GO:0060968 regulation of gene silencing 5/244 81/18722 0.00413757518079097 0.0530890936869414 KCNQ1OT1/MPHOSPH8/TNRC6B/PUM1/DDX5 5 GO:0030326 embryonic limb morphogenesis 6/244 116/18722 0.0041521293601777 0.0530890936869414 FBN2/LRP5/FRAS1/BMP7/PBX1/GLI3 6 GO:0035113 embryonic appendage morphogenesis 6/244 116/18722 0.0041521293601777 0.0530890936869414 FBN2/LRP5/FRAS1/BMP7/PBX1/GLI3 6 GO:0030900 forebrain development 12/244 379/18722 0.00423467054050338 0.0537263606026799 LRP2/NR2F2/LRP1/NRP2/LAMB1/ISL1/APP/PGAP1/ATP2B4/GLI3/CDH1/TSKU 12 GO:0051346 negative regulation of hydrolase activity 12/244 379/18722 0.00423467054050338 0.0537263606026799 LRP1/APLP2/SPINT1/APP/ITIH5/GAPDH/CPAMD8/SERPINH1/DHCR24/AMOT/SERPINE2/CST3 12 GO:0045664 regulation of neuron differentiation 8/244 196/18722 0.00426273691925764 0.0538744366026177 ISL1/SLC6A4/BMP7/APP/TUG1/PBX1/DPYSL2/GLI3 8 GO:0060395 SMAD protein signal transduction 5/244 82/18722 0.00436039666372807 0.0548975610613427 JUN/LRP1/NCEH1/BMP7/SPTBN1 5 GO:0032535 regulation of cellular component size 12/244 382/18722 0.00450580708495192 0.0560655767163219 SVIL/LRP1/PPP1R9A/SEMA6A/SEMA6D/KANK1/KCNN4/IQGAP2/DPYSL2/MACF1/SPTBN1/SLC12A9 12 GO:0030203 glycosaminoglycan metabolic process 6/244 118/18722 0.00451340584184839 0.0560655767163219 ITIH5/NAGLU/GNS/GCNT2/FOXC1/HYAL2 6 GO:0006027 glycosaminoglycan catabolic process 3/244 26/18722 0.00455554138261045 0.0560655767163219 NAGLU/GNS/HYAL2 3 GO:0006760 folic acid-containing compound metabolic process 3/244 26/18722 0.00455554138261045 0.0560655767163219 FOLR1/SLC46A1/SLC19A1 3 GO:0021680 cerebellar Purkinje cell layer development 3/244 26/18722 0.00455554138261045 0.0560655767163219 NAGLU/HSPA5/RERE 3 GO:0060037 pharyngeal system development 3/244 26/18722 0.00455554138261045 0.0560655767163219 ISL1/BMP7/FOLR1 3 GO:0001837 epithelial to mesenchymal transition 7/244 157/18722 0.00457435263714277 0.056087025244967 ISL1/BMP7/DAG1/TGFBR3/DDX5/GCNT2/FOXC1 7 GO:0048678 response to axon injury 5/244 83/18722 0.00459164138476987 0.0560897159492706 LRP1/ISL1/DAG1/FOLR1/MTR 5 GO:0010718 positive regulation of epithelial to mesenchymal transition 4/244 52/18722 0.00466878119416955 0.0564029963383866 ISL1/BMP7/GCNT2/FOXC1 4 GO:0021545 cranial nerve development 4/244 52/18722 0.00466878119416955 0.0564029963383866 NRP2/ISL1/GLI3/SLC1A3 4 GO:0060147 regulation of posttranscriptional gene silencing 4/244 52/18722 0.00466878119416955 0.0564029963383866 KCNQ1OT1/TNRC6B/PUM1/DDX5 4 GO:0045216 cell-cell junction organization 8/244 200/18722 0.00480879336351423 0.0578816666392226 NLGN4X/POF1B/CLDN4/GJA5/VCL/GJA1/DSG2/CDH1 8 GO:0007389 pattern specification process 13/244 436/18722 0.00489537864197989 0.0583067941928266 LRP2/LRP5/NR2F2/NRP2/ISL1/GALNT11/BMP7/PGAP1/FOLR1/PBX1/WLS/GLI3/FOXC1 13 GO:0032411 positive regulation of transporter activity 6/244 120/18722 0.00489734485612299 0.0583067941928266 TCAF1/CALM1/AKAP9/P2RY6/HTT/STIM1 6 GO:0048593 camera-type eye morphogenesis 6/244 120/18722 0.00489734485612299 0.0583067941928266 LRP5/TENM3/BMP7/NAGLU/GLI3/TSKU 6 GO:0009100 glycoprotein metabolic process 12/244 387/18722 0.00498849338704683 0.0590904694074145 GALNT11/CTSL/MANBA/ITM2B/MAN2A2/EXTL2/FUT8/GANAB/TMTC3/RPN2/GCNT2/CST3 12 GO:0060966 regulation of gene silencing by RNA 4/244 53/18722 0.004999132834833 0.0590904694074145 KCNQ1OT1/TNRC6B/PUM1/DDX5 4 GO:0001656 metanephros development 5/244 85/18722 0.005080080058584 0.0598320540233227 FBN1/FRAS1/BMP7/LGR4/GLI3 5 GO:0086002 cardiac muscle cell action potential involved in contraction 4/244 54/18722 0.0053448039157122 0.0627250916679653 GJA5/DSC2/GJA1/DSG2 4 GO:1901888 regulation of cell junction assembly 8/244 204/18722 0.00540699365493165 0.0632291144131865 EFNA5/LRP1/PPP1R9A/APP/VCL/GJA1/MACF1/SLK 8 GO:0060348 bone development 8/244 205/18722 0.00556505497865821 0.0647006397127011 FBN1/LRP5/BBX/SERPINH1/GJA1/GLI3/FOXC1/TSKU 8 GO:0048041 focal adhesion assembly 5/244 87/18722 0.00560424221043064 0.0647006397127011 EFNA5/LRP1/VCL/MACF1/SLK 5 GO:0150104 transport across blood-brain barrier 5/244 87/18722 0.00560424221043064 0.0647006397127011 LRP2/LRP1/ATP2B4/SLC19A1/SLC1A3 5 GO:0006516 glycoprotein catabolic process 3/244 28/18722 0.00563127904985773 0.0647006397127011 CTSL/MANBA/CST3 3 GO:1903779 regulation of cardiac conduction 3/244 28/18722 0.00563127904985773 0.0647006397127011 ATP2B1/GJA5/ATP2B4 3 GO:0061614 pri-miRNA transcription by RNA polymerase II 4/244 55/18722 0.00570610315130868 0.0653318987986074 JUN/TEAD1/SREBF2/DDX5 4 GO:0010720 positive regulation of cell development 10/244 298/18722 0.0058881841596119 0.0671825456544608 LRP2/LRP1/IL6ST/SPINT1/DAG1/P4HB/MACF1/CUX1/GLI3/SERPINE2 10 GO:1904645 response to amyloid-beta 4/244 56/18722 0.00608333338873764 0.069168974101702 LRP1/APP/GJA1/LGMN 4 GO:0042063 gliogenesis 10/244 301/18722 0.00630364893772877 0.0714268634806094 LRP2/ITGB4/LRP1/LAMB1/IL6ST/SPINT1/APP/DAG1/GLI3/SERPINE2 10 GO:1903034 regulation of response to wounding 7/244 167/18722 0.0063746781454611 0.0719834789896398 LRP1/KANK1/CLDN4/ITGB1/GJA1/PLPP3/SERPINE2 7 GO:0007623 circadian rhythm 8/244 210/18722 0.00640888112257989 0.0721218608520463 JUN/ADRB1/SLC6A4/CLDN4/NAGLU/HUWE1/LGR4/GNAQ 8 GO:0050891 multicellular organismal water homeostasis 4/244 57/18722 0.00647679146089841 0.0723902610221503 CLDN4/MET/ATP6V1B1/HYAL2 4 GO:1900024 regulation of substrate adhesion-dependent cell spreading 4/244 57/18722 0.00647679146089841 0.0723902610221503 EFNA5/KANK1/TACSTD2/P4HB 4 GO:0007162 negative regulation of cell adhesion 10/244 303/18722 0.0065930702346607 0.0731919891591049 EFNA5/LRP1/SEMA6A/KANK1/TACSTD2/MIA3/GLI3/CDH1/SERPINE2/GCNT2 10 GO:0015849 organic acid transport 10/244 303/18722 0.0065930702346607 0.0731919891591049 LRP2/SLC26A2/ITGB1/FOLR1/SLC46A1/SLC38A9/SLC27A2/GJA1/SLC19A1/SLC1A3 10 GO:0090287 regulation of cellular response to growth factor stimulus 10/244 304/18722 0.00674160219736793 0.0740100309335228 LRP2/FBN1/FBN2/SEMA6A/LATS2/PEG10/FOLR1/HSPA5/ATP2B4/TGFBR3 10 GO:0072080 nephron tubule development 5/244 91/18722 0.0067650654412761 0.0740100309335228 TACSTD2/PBX1/LAMA5/LGR4/GLI3 5 GO:0000132 establishment of mitotic spindle orientation 3/244 30/18722 0.00684694138885908 0.0740100309335228 ITGB1/GJA1/HTT 3 GO:0010800 positive regulation of peptidyl-threonine phosphorylation 3/244 30/18722 0.00684694138885908 0.0740100309335228 BMP7/APP/CALM1 3 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 3/244 30/18722 0.00684694138885908 0.0740100309335228 CTSL/CTSV/LGMN 3 GO:0060674 placenta blood vessel development 3/244 30/18722 0.00684694138885908 0.0740100309335228 NR2F2/SPINT1/ITGB8 3 GO:0061384 heart trabecula morphogenesis 3/244 30/18722 0.00684694138885908 0.0740100309335228 ADAMTS1/BMP7/TGFBR3 3 GO:2000637 positive regulation of gene silencing by miRNA 3/244 30/18722 0.00684694138885908 0.0740100309335228 TNRC6B/PUM1/DDX5 3 GO:0043666 regulation of phosphoprotein phosphatase activity 4/244 58/18722 0.00688676804991434 0.0741488174444922 SLC39A10/CALM1/RCAN1/HTT 4 GO:0006022 aminoglycan metabolic process 6/244 129/18722 0.00692747624937891 0.0741488174444922 ITIH5/NAGLU/GNS/GCNT2/FOXC1/HYAL2 6 GO:0007498 mesoderm development 6/244 129/18722 0.00692747624937891 0.0741488174444922 ITGB4/BMP7/ITGB1/WLS/GJA1/FOXC1 6 GO:0021932 hindbrain radial glia guided cell migration 2/244 10/18722 0.00710502865081532 0.0750711387349811 ITGB1/RERE 2 GO:0036363 transforming growth factor beta activation 2/244 10/18722 0.00710502865081532 0.0750711387349811 ITGAV/ITGB8 2 GO:0040015 negative regulation of multicellular organism growth 2/244 10/18722 0.00710502865081532 0.0750711387349811 ADRB1/LGMN 2 GO:1904350 regulation of protein catabolic process in the vacuole 2/244 10/18722 0.00710502865081532 0.0750711387349811 LRP2/LRP1 2 GO:0001666 response to hypoxia 10/244 307/18722 0.00720283734534325 0.0758606522974292 TBL2/MALAT1/SLC6A4/BMP7/LDHA/SOD3/P4HB/DPP4/TGFBR3/DNMT3A 10 GO:0090303 positive regulation of wound healing 4/244 59/18722 0.00731354756050322 0.0760333751622368 KANK1/CLDN4/ITGB1/PLPP3 4 GO:1904062 regulation of cation transmembrane transport 11/244 357/18722 0.00737916406888193 0.0760333751622368 UTRN/KCNN4/APP/CALM1/AHNAK/AKAP9/ITGB1/P2RY6/ATP2B4/HTT/STIM1 11 GO:0033273 response to vitamin 5/244 93/18722 0.00740434572486786 0.0760333751622368 ATP2B1/BMP7/FOLR1/SRSF2/DNMT3A 5 GO:0045185 maintenance of protein location 5/244 93/18722 0.00740434572486786 0.0760333751622368 FBN1/FBN2/DZIP1/HSPA5/GJA1 5 GO:0051591 response to cAMP 5/244 93/18722 0.00740434572486786 0.0760333751622368 JUN/APP/LDHA/AKAP9/HSPA5 5 GO:0060349 bone morphogenesis 5/244 93/18722 0.00740434572486786 0.0760333751622368 LRP5/SERPINH1/GLI3/FOXC1/TSKU 5 GO:0097306 cellular response to alcohol 5/244 93/18722 0.00740434572486786 0.0760333751622368 ATP2B1/DAG1/P2RY6/CDH1/DNMT3A 5 GO:1901019 regulation of calcium ion transmembrane transporter activity 5/244 93/18722 0.00740434572486786 0.0760333751622368 CALM1/AHNAK/P2RY6/HTT/STIM1 5 GO:0060148 positive regulation of posttranscriptional gene silencing 3/244 31/18722 0.00750858483879943 0.0766248750940837 TNRC6B/PUM1/DDX5 3 GO:0071711 basement membrane organization 3/244 31/18722 0.00750858483879943 0.0766248750940837 LAMB1/DAG1/ITGB1 3 GO:0045667 regulation of osteoblast differentiation 6/244 132/18722 0.00772271683325287 0.0781927690113077 FBN2/LRP5/IL6ST/BMP7/GLI3/DDX5 6 GO:0031638 zymogen activation 4/244 60/18722 0.00775740800294775 0.0781927690113077 CTSL/DHCR24/LGMN/SERPINE2 4 GO:0055008 cardiac muscle tissue morphogenesis 4/244 60/18722 0.00775740800294775 0.0781927690113077 LRP2/ISL1/TGFBR3/FOXC1 4 GO:0060038 cardiac muscle cell proliferation 4/244 60/18722 0.00775740800294775 0.0781927690113077 JARID2/GJA1/TGFBR3/FOXC1 4 GO:0007584 response to nutrient 7/244 174/18722 0.00791746716190844 0.0795620706239485 ATP2B1/SLC6A4/BMP7/LDHA/FOLR1/SRSF2/DNMT3A 7 GO:0006942 regulation of striated muscle contraction 5/244 95/18722 0.00808458328931303 0.0797850458359821 CALM1/GJA5/AKAP9/DSC2/DSG2 5 GO:0008593 regulation of Notch signaling pathway 5/244 95/18722 0.00808458328931303 0.0797850458359821 IL6ST/GALNT11/BMP7/AAK1/SREBF2 5 GO:0030516 regulation of axon extension 5/244 95/18722 0.00808458328931303 0.0797850458359821 LRP1/SEMA6A/SEMA6D/DPYSL2/MACF1 5 GO:0050954 sensory perception of mechanical stimulus 7/244 175/18722 0.0081585135965989 0.0797850458359821 LRP2/PGAP1/ATP6V1B1/SLC52A3/TBL1X/SERPINE2/SLC1A3 7 GO:0052126 movement in host environment 7/244 175/18722 0.0081585135965989 0.0797850458359821 CTSL/ITGAV/DAG1/ITGB1/P4HB/DPP4/HYAL2 7 GO:0034764 positive regulation of transmembrane transport 8/244 219/18722 0.00816816821511062 0.0797850458359821 TCAF1/KCNN4/CALM1/AKAP9/ITGB1/P2RY6/HTT/STIM1 8 GO:0006026 aminoglycan catabolic process 3/244 32/18722 0.00820673934648872 0.0797850458359821 NAGLU/GNS/HYAL2 3 GO:0007435 salivary gland morphogenesis 3/244 32/18722 0.00820673934648872 0.0797850458359821 BMP7/DAG1/LAMA5 3 GO:0010644 cell communication by electrical coupling 3/244 32/18722 0.00820673934648872 0.0797850458359821 CALM1/GJA5/GJA1 3 GO:0051497 negative regulation of stress fiber assembly 3/244 32/18722 0.00820673934648872 0.0797850458359821 PPP1R9A/TACSTD2/MET 3 GO:0060914 heart formation 3/244 32/18722 0.00820673934648872 0.0797850458359821 LRP2/ISL1/FOLR1 3 GO:0061041 regulation of wound healing 6/244 134/18722 0.0082881606010005 0.0803389254716449 KANK1/CLDN4/ITGB1/GJA1/PLPP3/SERPINE2 6 GO:0003073 regulation of systemic arterial blood pressure 5/244 96/18722 0.0084404540330038 0.0808329229134751 NR2F2/ADRB1/GJA5/GJA1/ENPEP 5 GO:0010769 regulation of cell morphogenesis involved in differentiation 5/244 96/18722 0.0084404540330038 0.0808329229134751 EFNA5/KANK1/TACSTD2/P4HB/CUX1 5 GO:0016032 viral process 12/244 415/18722 0.00850644270136148 0.0808329229134751 JUN/MPHOSPH8/CTSL/ITGAV/DAG1/ITGB1/HACD3/FUT8/P4HB/DPP4/DDX5/HYAL2 12 GO:0003093 regulation of glomerular filtration 2/244 11/18722 0.00860971485688262 0.0808329229134751 GJA5/GJA1 2 GO:0003139 secondary heart field specification 2/244 11/18722 0.00860971485688262 0.0808329229134751 LRP2/ISL1 2 GO:0019048 modulation by virus of host process 2/244 11/18722 0.00860971485688262 0.0808329229134751 DAG1/HYAL2 2 GO:0033690 positive regulation of osteoblast proliferation 2/244 11/18722 0.00860971485688262 0.0808329229134751 LRP5/ITGAV 2 GO:0035581 sequestering of extracellular ligand from receptor 2/244 11/18722 0.00860971485688262 0.0808329229134751 FBN1/FBN2 2 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport 2/244 11/18722 0.00860971485688262 0.0808329229134751 SLC35D1/SLC35A4 2 GO:1902337 regulation of apoptotic process involved in morphogenesis 2/244 11/18722 0.00860971485688262 0.0808329229134751 BMP7/FOXC1 2 GO:1903961 positive regulation of anion transmembrane transport 2/244 11/18722 0.00860971485688262 0.0808329229134751 TCAF1/ITGB1 2 GO:0032835 glomerulus development 4/244 62/18722 0.0086974511148136 0.0809626752500779 BMP7/ENPEP/LGR4/FOXC1 4 GO:0060113 inner ear receptor cell differentiation 4/244 62/18722 0.0086974511148136 0.0809626752500779 MCOLN3/NAGLU/IFT27/TSKU 4 GO:1903078 positive regulation of protein localization to plasma membrane 4/244 62/18722 0.0086974511148136 0.0809626752500779 LRP1/ITGB1/ATP2B4/SPTBN1 4 GO:0070252 actin-mediated cell contraction 5/244 97/18722 0.00880703251549395 0.0817511549319579 GJA5/AKAP9/DSC2/GJA1/DSG2 5 GO:0019058 viral life cycle 10/244 317/18722 0.0089187579005325 0.0823049565886733 MPHOSPH8/CTSL/ITGAV/DAG1/ITGB1/HACD3/P4HB/DPP4/DDX5/HYAL2 10 GO:0003382 epithelial cell morphogenesis 3/244 33/18722 0.00894183490631661 0.0823049565886733 POF1B/PALLD/MET 3 GO:0048333 mesodermal cell differentiation 3/244 33/18722 0.00894183490631661 0.0823049565886733 ITGB4/ITGB1/GJA1 3 GO:0001701 in utero embryonic development 11/244 367/18722 0.00897606521895558 0.0823892466745476 NR2F2/SPINT1/BMP7/ITGB1/FUT8/KIDINS220/GLI3/AMOT/HOPX/FOXC1/KRT19 11 GO:0050714 positive regulation of protein secretion 6/244 137/18722 0.00919124351234551 0.0838956282821315 LRP1/ISL1/KCNN4/WLS/GJA1/MYH10 6 GO:0060048 cardiac muscle contraction 6/244 137/18722 0.00919124351234551 0.0838956282821315 CALM1/GJA5/AKAP9/DSC2/GJA1/DSG2 6 GO:0010721 negative regulation of cell development 7/244 180/18722 0.00944564048121468 0.0853546165999431 FBN1/EFNA5/SEMA6A/SEMA6D/KANK1/TACSTD2/BMP7 7 GO:0015698 inorganic anion transport 7/244 180/18722 0.00944564048121468 0.0853546165999431 SLC26A2/CLDN4/P2RY6/SLC22A11/GABRE/SLC12A9/SLC1A3 7 GO:0071496 cellular response to external stimulus 10/244 320/18722 0.00949020557504015 0.0853546165999431 JUN/TBL2/ATP2B1/CTSV/DAG1/FOLR1/TMEM150C/HSPA5/GJA1/SREBF2 10 GO:0035107 appendage morphogenesis 6/244 138/18722 0.00950731007664169 0.0853546165999431 FBN2/LRP5/FRAS1/BMP7/PBX1/GLI3 6 GO:0035108 limb morphogenesis 6/244 138/18722 0.00950731007664169 0.0853546165999431 FBN2/LRP5/FRAS1/BMP7/PBX1/GLI3 6 GO:0010001 glial cell differentiation 8/244 225/18722 0.00952772459024169 0.0853546165999431 ITGB4/LRP1/IL6ST/SPINT1/APP/DAG1/GLI3/SERPINE2 8 GO:0031667 response to nutrient levels 13/244 474/18722 0.00956677688167056 0.0853546165999431 JUN/TBL2/ADRB1/ATP2B1/SLC6A4/BMP7/LDHA/CTSV/FOLR1/HSPA5/SRSF2/SREBF2/DNMT3A 13 GO:0010717 regulation of epithelial to mesenchymal transition 5/244 99/18722 0.00957292192168731 0.0853546165999431 ISL1/BMP7/DAG1/GCNT2/FOXC1 5 GO:0051962 positive regulation of nervous system development 9/244 272/18722 0.009584861085021 0.0853546165999431 LRP2/LRP1/IL6ST/SPINT1/DAG1/MACF1/CUX1/GLI3/SERPINE2 9 GO:0030104 water homeostasis 4/244 64/18722 0.00970898970617899 0.085400179399262 CLDN4/MET/ATP6V1B1/HYAL2 4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 3/244 34/18722 0.00971426515301041 0.085400179399262 CTSL/CTSV/LGMN 3 GO:0007431 salivary gland development 3/244 34/18722 0.00971426515301041 0.085400179399262 BMP7/DAG1/LAMA5 3 GO:0055094 response to lipoprotein particle 3/244 34/18722 0.00971426515301041 0.085400179399262 ITGB1/MIA3/SREBF2 3 GO:0008361 regulation of cell size 7/244 181/18722 0.00971992303570419 0.085400179399262 LRP1/SEMA6A/SEMA6D/KCNN4/DPYSL2/MACF1/SLC12A9 7 GO:0036293 response to decreased oxygen levels 10/244 322/18722 0.00988646038306933 0.0865296097340812 TBL2/MALAT1/SLC6A4/BMP7/LDHA/SOD3/P4HB/DPP4/TGFBR3/DNMT3A 10 GO:0030177 positive regulation of Wnt signaling pathway 6/244 140/18722 0.01016258679746 0.0865296097340812 LGR5/KANK1/WLS/MACF1/LGR4/TBL1X 6 GO:0031333 negative regulation of protein-containing complex assembly 6/244 140/18722 0.01016258679746 0.0865296097340812 SVIL/ISL1/KANK1/HSPA5/SPTBN1/SVIP 6 GO:1905330 regulation of morphogenesis of an epithelium 4/244 65/18722 0.0102421941078023 0.0865296097340812 TACSTD2/BMP7/GJA1/LGR4 4 GO:0007320 insemination 2/244 12/18722 0.0102434626252458 0.0865296097340812 SLC6A4/SERPINE2 2 GO:0009886 post-embryonic animal morphogenesis 2/244 12/18722 0.0102434626252458 0.0865296097340812 FBN1/EFEMP1 2 GO:0015780 nucleotide-sugar transmembrane transport 2/244 12/18722 0.0102434626252458 0.0865296097340812 SLC35D1/SLC35A4 2 GO:0031223 auditory behavior 2/244 12/18722 0.0102434626252458 0.0865296097340812 HTT/SLC1A3 2 GO:0061307 cardiac neural crest cell differentiation involved in heart development 2/244 12/18722 0.0102434626252458 0.0865296097340812 BMP7/FOLR1 2 GO:0061308 cardiac neural crest cell development involved in heart development 2/244 12/18722 0.0102434626252458 0.0865296097340812 BMP7/FOLR1 2 GO:0070493 thrombin-activated receptor signaling pathway 2/244 12/18722 0.0102434626252458 0.0865296097340812 IQGAP2/MET 2 GO:0071287 cellular response to manganese ion 2/244 12/18722 0.0102434626252458 0.0865296097340812 APP/HSPA5 2 GO:0098911 regulation of ventricular cardiac muscle cell action potential 2/244 12/18722 0.0102434626252458 0.0865296097340812 DSC2/DSG2 2 GO:1904748 regulation of apoptotic process involved in development 2/244 12/18722 0.0102434626252458 0.0865296097340812 BMP7/FOXC1 2 GO:1990034 calcium ion export across plasma membrane 2/244 12/18722 0.0102434626252458 0.0865296097340812 ATP2B1/CALM1 2 GO:0048024 regulation of mRNA splicing, via spliceosome 5/244 101/18722 0.0103834522344246 0.0874872411341515 SON/SRSF2/SF1/DDX5/RBM25 5 GO:0032355 response to estradiol 6/244 141/18722 0.0105019900013664 0.0875522544664551 NR2F2/SLC6A4/BMP7/MMP15/GJA1/DNMT3A 6 GO:0033157 regulation of intracellular protein transport 8/244 229/18722 0.0105234178973308 0.0875522544664551 TCAF1/HUWE1/GLI3/CDH1/LMAN1/SREBF2/SVIP/HYAL2 8 GO:0001893 maternal placenta development 3/244 35/18722 0.0105243884705568 0.0875522544664551 NR2F2/CTSV/GJA1 3 GO:0032232 negative regulation of actin filament bundle assembly 3/244 35/18722 0.0105243884705568 0.0875522544664551 PPP1R9A/TACSTD2/MET 3 GO:0040001 establishment of mitotic spindle localization 3/244 35/18722 0.0105243884705568 0.0875522544664551 ITGB1/GJA1/HTT 3 GO:2001257 regulation of cation channel activity 7/244 184/18722 0.0105777076160482 0.0877736041069047 APP/CALM1/AHNAK/ITGB1/P2RY6/HTT/STIM1 7 GO:1902476 chloride transmembrane transport 4/244 66/18722 0.0107940077963471 0.0893428453873968 SLC26A2/GABRE/SLC12A9/SLC1A3 4 GO:0016049 cell growth 13/244 482/18722 0.0108926673224991 0.0899329266877691 LRP1/NRP2/SEMA6A/SEMA6D/APP/ITGB1/DCBLD2/VCL/DPYSL2/GJA1/MACF1/SERPINE2/HYAL2 13 GO:0008217 regulation of blood pressure 7/244 186/18722 0.0111793518658266 0.0920474648284213 LRP5/NR2F2/ADRB1/ATP2B1/GJA5/GJA1/ENPEP 7 GO:0030010 establishment of cell polarity 6/244 143/18722 0.011204803996156 0.0920474648284213 KANK1/ITGB1/GJA1/WWC1/HTT/AMOT 6 GO:0014013 regulation of gliogenesis 5/244 103/18722 0.0112397945676408 0.0921046507463038 LRP2/IL6ST/SPINT1/DAG1/SERPINE2 5 GO:0042490 mechanoreceptor differentiation 4/244 67/18722 0.0113646614850399 0.0922719272650882 MCOLN3/NAGLU/IFT27/TSKU 4 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 3/244 36/18722 0.0113725290755815 0.0922719272650882 CTSL/CTSV/LGMN 3 GO:0010092 specification of animal organ identity 3/244 36/18722 0.0113725290755815 0.0922719272650882 LRP2/ISL1/GLI3 3 GO:0071402 cellular response to lipoprotein particle stimulus 3/244 36/18722 0.0113725290755815 0.0922719272650882 ITGB1/MIA3/SREBF2 3 GO:0007612 learning 6/244 144/18722 0.0115684039409108 0.0936299885463868 NLGN4X/JUN/APP/ITGB1/LGMN/HTT 6 GO:0048839 inner ear development 7/244 188/18722 0.0118054508055763 0.094809635472576 LGR5/MCOLN3/NAGLU/ATP6V1B1/IFT27/GLI3/TSKU 7 GO:0003002 regionalization 10/244 331/18722 0.0118280313403286 0.094809635472576 LRP2/LRP5/NR2F2/NRP2/ISL1/PGAP1/PBX1/WLS/GLI3/FOXC1 10 GO:0005513 detection of calcium ion 2/244 13/18722 0.0120026805710869 0.094809635472576 CALM1/STIM1 2 GO:0048711 positive regulation of astrocyte differentiation 2/244 13/18722 0.0120026805710869 0.094809635472576 IL6ST/SERPINE2 2 GO:0051481 negative regulation of cytosolic calcium ion concentration 2/244 13/18722 0.0120026805710869 0.094809635472576 LRP1/ATP2B1 2 GO:0060347 heart trabecula formation 2/244 13/18722 0.0120026805710869 0.094809635472576 ADAMTS1/TGFBR3 2 GO:1900115 extracellular regulation of signal transduction 2/244 13/18722 0.0120026805710869 0.094809635472576 FBN1/FBN2 2 GO:1900116 extracellular negative regulation of signal transduction 2/244 13/18722 0.0120026805710869 0.094809635472576 FBN1/FBN2 2 GO:1900272 negative regulation of long-term synaptic potentiation 2/244 13/18722 0.0120026805710869 0.094809635472576 PPP1R9A/APP 2 GO:1903054 negative regulation of extracellular matrix organization 2/244 13/18722 0.0120026805710869 0.094809635472576 DPP4/CST3 2 GO:0048846 axon extension involved in axon guidance 3/244 37/18722 0.0122589780756956 0.0961408161258606 NRP2/SEMA6A/SEMA6D 3 GO:0051294 establishment of spindle orientation 3/244 37/18722 0.0122589780756956 0.0961408161258606 ITGB1/GJA1/HTT 3 GO:1902284 neuron projection extension involved in neuron projection guidance 3/244 37/18722 0.0122589780756956 0.0961408161258606 NRP2/SEMA6A/SEMA6D 3 GO:0051216 cartilage development 7/244 190/18722 0.0124565347912892 0.0974575555337534 BMP7/ITGB8/SERPINH1/GLI3/EFEMP1/HYAL2/TSKU 7 GO:0034765 regulation of ion transmembrane transport 13/244 491/18722 0.0125509195766989 0.097748346964984 TCAF1/UTRN/KCNN4/APP/CALM1/AHNAK/GJA5/AKAP9/ITGB1/P2RY6/ATP2B4/HTT/STIM1 13 GO:1904377 positive regulation of protein localization to cell periphery 4/244 69/18722 0.012563376561472 0.097748346964984 LRP1/ITGB1/ATP2B4/SPTBN1 4 GO:0090263 positive regulation of canonical Wnt signaling pathway 5/244 106/18722 0.0126126899309657 0.097748346964984 LGR5/KANK1/WLS/LGR4/TBL1X 5 GO:1905477 positive regulation of protein localization to membrane 5/244 106/18722 0.0126126899309657 0.097748346964984 LRP1/TCAF1/ITGB1/ATP2B4/SPTBN1 5 GO:0043484 regulation of RNA splicing 6/244 148/18722 0.0131062630556242 0.101281461257233 AHNAK/SON/SRSF2/SF1/DDX5/RBM25 6 GO:0002478 antigen processing and presentation of exogenous peptide antigen 3/244 38/18722 0.013183994503311 0.101281461257233 CTSL/CTSV/LGMN 3 GO:0042596 fear response 3/244 38/18722 0.013183994503311 0.101281461257233 ADRB1/DPP4/GJA1 3 GO:0060415 muscle tissue morphogenesis 4/244 70/18722 0.0131918640955861 0.101281461257233 LRP2/ISL1/TGFBR3/FOXC1 4 GO:0032386 regulation of intracellular transport 10/244 337/18722 0.0132742393765178 0.101676341704516 TCAF1/PGAP1/WWC1/HUWE1/GLI3/CDH1/LMAN1/SREBF2/SVIP/HYAL2 10 GO:0007565 female pregnancy 7/244 193/18722 0.0134811558549167 0.103021111951759 ITGB4/NR2F2/CLDN4/CTSV/GJA1/SLC19A1/MAGED2 7 GO:0022411 cellular component disassembly 12/244 443/18722 0.0137229784776255 0.103923292975298 SVIL/LAMC1/LRP1/CALM1/CTSV/DPP4/MMP15/HUWE1/SPTBN1/HTT/SREBF2/CST3 12 GO:0051960 regulation of nervous system development 12/244 443/18722 0.0137229784776255 0.103923292975298 LRP2/LRP1/SEMA6A/IL6ST/SEMA6D/SPINT1/BMP7/DAG1/MACF1/CUX1/GLI3/SERPINE2 12 GO:0007568 aging 10/244 339/18722 0.0137846870059334 0.103923292975298 JUN/LRP1/PPP1R9A/ATP2B1/APP/CTSV/DAG1/RPN2/DNMT3A/HYAL2 10 GO:0003208 cardiac ventricle morphogenesis 4/244 71/18722 0.0138400438542032 0.103923292975298 LRP2/ISL1/TGFBR3/FOXC1 4 GO:0033555 multicellular organismal response to stress 4/244 71/18722 0.0138400438542032 0.103923292975298 ADRB1/DPP4/GJA1/VWA1 4 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis 2/244 14/18722 0.013883848331149 0.103923292975298 SERPINH1/TSKU 2 GO:0007638 mechanosensory behavior 2/244 14/18722 0.013883848331149 0.103923292975298 HTT/SLC1A3 2 GO:0035437 maintenance of protein localization in endoplasmic reticulum 2/244 14/18722 0.013883848331149 0.103923292975298 HSPA5/GJA1 2 GO:0044764 multi-organism cellular process 2/244 14/18722 0.013883848331149 0.103923292975298 CTSL/HYAL2 2 GO:0044403 biological process involved in symbiotic interaction 9/244 290/18722 0.0141041828392287 0.105070514765387 JUN/CTSL/ITGAV/GAPDH/DAG1/ITGB1/P4HB/DPP4/HYAL2 9 GO:0007618 mating 3/244 39/18722 0.0141478063254159 0.105070514765387 SLC6A4/APP/SERPINE2 3 GO:1902742 apoptotic process involved in development 3/244 39/18722 0.0141478063254159 0.105070514765387 LRP5/BMP7/FOXC1 3 GO:0010975 regulation of neuron projection development 12/244 445/18722 0.0141725252337454 0.105070514765387 LRP1/PPP1R9A/SEMA6A/SEMA6D/TENM3/KANK1/BMP7/HSPA5/KIDINS220/MACF1/CUX1/TSKU 12 GO:0030705 cytoskeleton-dependent intracellular transport 7/244 195/18722 0.0141969898222252 0.105070514765387 ARMCX3/DST/APP/SYNE2/HOOK2/IFT27/HTT 7 GO:1904064 positive regulation of cation transmembrane transport 6/244 151/18722 0.0143498425571572 0.105963107062513 KCNN4/CALM1/AKAP9/P2RY6/HTT/STIM1 6 GO:0006979 response to oxidative stress 12/244 446/18722 0.0144014709781884 0.106105905009702 JUN/SCARA3/BMP7/APP/LDHA/SOD3/MET/FUT8/P4HB/RCAN1/DHCR24/HYAL2 12 GO:0001933 negative regulation of protein phosphorylation 10/244 342/18722 0.0145778014906462 0.107164777848464 LRP5/NR2F2/LRP1/LATS2/BMP7/CALM1/PLPP3/GNAQ/CTDSPL/HYAL2 10 GO:0061387 regulation of extent of cell growth 5/244 110/18722 0.0146139169207256 0.1071904709855 LRP1/SEMA6A/SEMA6D/DPYSL2/MACF1 5 GO:0030501 positive regulation of bone mineralization 3/244 40/18722 0.0151506114297919 0.11023154505673 FBN2/ATP2B1/BMP7 3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 3/244 40/18722 0.0151506114297919 0.11023154505673 CALM1/P2RY6/HTT 3 GO:0035924 cellular response to vascular endothelial growth factor stimulus 4/244 73/18722 0.0151962537768407 0.11023154505673 NRP2/SEMA6A/ATP2B4/FOXC1 4 GO:0050848 regulation of calcium-mediated signaling 4/244 73/18722 0.0151962537768407 0.11023154505673 CALM1/RCAN1/ATP2B4/HTT 4 GO:1904427 positive regulation of calcium ion transmembrane transport 4/244 73/18722 0.0151962537768407 0.11023154505673 CALM1/P2RY6/HTT/STIM1 4 GO:0007605 sensory perception of sound 6/244 154/18722 0.0156733888101073 0.111499708593725 LRP2/PGAP1/ATP6V1B1/SLC52A3/TBL1X/SLC1A3 6 GO:0016052 carbohydrate catabolic process 6/244 154/18722 0.0156733888101073 0.111499708593725 LRP5/MANBA/APP/LDHA/GAPDH/FUT8 6 GO:0003012 muscle system process 12/244 452/18722 0.0158348842495075 0.111499708593725 UTRN/IL6ST/ATP2B1/CALM1/GJA5/AKAP9/DAG1/JARID2/DSC2/GJA1/ATP2B4/DSG2 12 GO:0019511 peptidyl-proline hydroxylation 2/244 15/18722 0.0158835153349907 0.111499708593725 P3H2/P4HB 2 GO:0042074 cell migration involved in gastrulation 2/244 15/18722 0.0158835153349907 0.111499708593725 LRP5/AMOT 2 GO:0050746 regulation of lipoprotein metabolic process 2/244 15/18722 0.0158835153349907 0.111499708593725 ITGAV/SVIP 2 GO:0051938 L-glutamate import 2/244 15/18722 0.0158835153349907 0.111499708593725 ITGB1/SLC1A3 2 GO:0070831 basement membrane assembly 2/244 15/18722 0.0158835153349907 0.111499708593725 LAMB1/DAG1 2 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade 2/244 15/18722 0.0158835153349907 0.111499708593725 RCAN1/ATP2B4 2 GO:0098712 L-glutamate import across plasma membrane 2/244 15/18722 0.0158835153349907 0.111499708593725 ITGB1/SLC1A3 2 GO:0098760 response to interleukin-7 2/244 15/18722 0.0158835153349907 0.111499708593725 P4HB/PDIA3 2 GO:0098761 cellular response to interleukin-7 2/244 15/18722 0.0158835153349907 0.111499708593725 P4HB/PDIA3 2 GO:0106057 negative regulation of calcineurin-mediated signaling 2/244 15/18722 0.0158835153349907 0.111499708593725 RCAN1/ATP2B4 2 GO:1905146 lysosomal protein catabolic process 2/244 15/18722 0.0158835153349907 0.111499708593725 LRP2/LRP1 2 GO:2001028 positive regulation of endothelial cell chemotaxis 2/244 15/18722 0.0158835153349907 0.111499708593725 MET/LGMN 2 GO:0048193 Golgi vesicle transport 9/244 296/18722 0.0159139876233893 0.111499708593725 PGAP1/MIA3/MACF1/CUX1/TMED3/SPTBN1/HTT/PLPP3/LMAN1 9 GO:0070482 response to oxygen levels 10/244 347/18722 0.0159748623532674 0.111688080197525 TBL2/MALAT1/SLC6A4/BMP7/LDHA/SOD3/P4HB/DPP4/TGFBR3/DNMT3A 10 GO:0042307 positive regulation of protein import into nucleus 3/244 41/18722 0.0161925785881485 0.112730536526813 GLI3/CDH1/HYAL2 3 GO:0071634 regulation of transforming growth factor beta production 3/244 41/18722 0.0161925785881485 0.112730536526813 ITGAV/ITGB8/TSKU 3 GO:0033002 muscle cell proliferation 8/244 248/18722 0.0163335468578038 0.113471532716159 JUN/ADAMTS1/P2RY6/JARID2/GJA1/SF1/TGFBR3/FOXC1 8 GO:0009952 anterior/posterior pattern specification 7/244 201/18722 0.0165073045480016 0.114436714651336 LRP5/NR2F2/PGAP1/PBX1/WLS/GLI3/FOXC1 7 GO:2001259 positive regulation of cation channel activity 4/244 75/18722 0.016633481941048 0.115068677175334 CALM1/P2RY6/HTT/STIM1 4 GO:0046660 female sex differentiation 5/244 114/18722 0.0168177949040653 0.116070390396859 LRP2/NR2F2/ADAMTS1/HSPA5/FOXC1 5 GO:0009314 response to radiation 12/244 456/18722 0.0168489276382538 0.116070390396859 JUN/LRP5/SCARA3/APP/CDS1/ITGB1/HSPA5/XRRA1/GNAQ/DNMT3A/HYAL2/SLC1A3 12 GO:0032388 positive regulation of intracellular transport 7/244 202/18722 0.0169167551004282 0.116293843640182 TCAF1/PGAP1/HUWE1/GLI3/CDH1/SREBF2/HYAL2 7 GO:0007030 Golgi organization 6/244 157/18722 0.0170792199983738 0.117165588548343 AKAP9/GOLGB1/HUWE1/TMED3/HTT/LMAN1 6 GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II 3/244 42/18722 0.0172738483966388 0.118253887148657 JUN/TEAD1/SREBF2 3 GO:0051701 biological process involved in interaction with host 7/244 203/18722 0.0173333397245805 0.118261354220959 CTSL/ITGAV/DAG1/ITGB1/P4HB/DPP4/HYAL2 7 GO:0014855 striated muscle cell proliferation 4/244 76/18722 0.0173829075133059 0.118261354220959 JARID2/GJA1/TGFBR3/FOXC1 4 GO:0045685 regulation of glial cell differentiation 4/244 76/18722 0.0173829075133059 0.118261354220959 IL6ST/SPINT1/DAG1/SERPINE2 4 GO:0006066 alcohol metabolic process 10/244 353/18722 0.0177800570129158 0.120208155431801 LRP5/APP/P2RY6/ACSS1/DHCR24/ASAH1/PLPP3/SREBF2/RDH14/TSKU 10 GO:0031346 positive regulation of cell projection organization 10/244 353/18722 0.0177800570129158 0.120208155431801 LRP1/PPP1R9A/TENM3/BMP7/DZIP1/HSPA5/KIDINS220/MACF1/CUX1/HTT 10 GO:0061448 connective tissue development 8/244 252/18722 0.0178043119851538 0.120208155431801 LRP5/BMP7/ITGB8/SERPINH1/GLI3/EFEMP1/HYAL2/TSKU 8 GO:0055074 calcium ion homeostasis 12/244 460/18722 0.0179112821038072 0.120208155431801 LRP1/MCOLN3/ATP2B1/APP/CALM1/ITGAV/ATP6V1B1/P2RY6/GJA1/ATP2B4/HTT/STIM1 12 GO:0001977 renal system process involved in regulation of blood volume 2/244 16/18722 0.0179982995959971 0.120208155431801 GJA5/GJA1 2 GO:0017014 protein nitrosylation 2/244 16/18722 0.0179982995959971 0.120208155431801 GAPDH/ATP2B4 2 GO:0018119 peptidyl-cysteine S-nitrosylation 2/244 16/18722 0.0179982995959971 0.120208155431801 GAPDH/ATP2B4 2 GO:0021535 cell migration in hindbrain 2/244 16/18722 0.0179982995959971 0.120208155431801 ITGB1/RERE 2 GO:0034116 positive regulation of heterotypic cell-cell adhesion 2/244 16/18722 0.0179982995959971 0.120208155431801 BMP7/GCNT2 2 GO:0007492 endoderm development 4/244 77/18722 0.0181530888282645 0.120751113136999 LAMC1/LAMB1/ITGAV/MMP15 4 GO:0048644 muscle organ morphogenesis 4/244 77/18722 0.0181530888282645 0.120751113136999 LRP2/ISL1/TGFBR3/FOXC1 4 GO:0001504 neurotransmitter uptake 3/244 43/18722 0.0183945341942133 0.121618590265966 SLC6A4/ITGB1/SLC1A3 3 GO:0071604 transforming growth factor beta production 3/244 43/18722 0.0183945341942133 0.121618590265966 ITGAV/ITGB8/TSKU 3 GO:1904591 positive regulation of protein import 3/244 43/18722 0.0183945341942133 0.121618590265966 GLI3/CDH1/HYAL2 3 GO:0090316 positive regulation of intracellular protein transport 6/244 160/18722 0.0185695740355444 0.122529357993572 TCAF1/HUWE1/GLI3/CDH1/SREBF2/HYAL2 6 GO:0043297 apical junction assembly 4/244 78/18722 0.0189441779593552 0.124658896047134 POF1B/CLDN4/VCL/GJA1 4 GO:0007611 learning or memory 8/244 255/18722 0.0189681825999899 0.124658896047134 NLGN4X/JUN/SLC6A4/APP/ITGB1/RCAN1/LGMN/HTT 8 GO:0022612 gland morphogenesis 5/244 118/18722 0.0192320103493716 0.126140491034002 LRP5/BMP7/DAG1/LAMA5/GLI3 5 GO:0048806 genitalia development 3/244 44/18722 0.0195547229592594 0.127493689770092 LRP2/DHCR24/LGR4 3 GO:1903214 regulation of protein targeting to mitochondrion 3/244 44/18722 0.0195547229592594 0.127493689770092 HUWE1/LMAN1/SREBF2 3 GO:1903573 negative regulation of response to endoplasmic reticulum stress 3/244 44/18722 0.0195547229592594 0.127493689770092 HSPA5/USP25/SVIP 3 GO:0051494 negative regulation of cytoskeleton organization 6/244 162/18722 0.0196111671148501 0.12760850522653 SVIL/PPP1R9A/KANK1/TACSTD2/MET/SPTBN1 6 GO:0010976 positive regulation of neuron projection development 6/244 163/18722 0.0201466033223124 0.129297620838096 LRP1/PPP1R9A/TENM3/BMP7/HSPA5/KIDINS220 6 GO:0016264 gap junction assembly 2/244 17/18722 0.0202248865218445 0.129297620838096 GJA5/GJA1 2 GO:0021924 cell proliferation in external granule layer 2/244 17/18722 0.0202248865218445 0.129297620838096 SLC6A4/RERE 2 GO:0021930 cerebellar granule cell precursor proliferation 2/244 17/18722 0.0202248865218445 0.129297620838096 SLC6A4/RERE 2 GO:0048532 anatomical structure arrangement 2/244 17/18722 0.0202248865218445 0.129297620838096 NRP2/HSPA5 2 GO:0055064 chloride ion homeostasis 2/244 17/18722 0.0202248865218445 0.129297620838096 ATP6V1B1/SLC12A9 2 GO:0055083 monovalent inorganic anion homeostasis 2/244 17/18722 0.0202248865218445 0.129297620838096 ATP6V1B1/SLC12A9 2 GO:0060977 coronary vasculature morphogenesis 2/244 17/18722 0.0202248865218445 0.129297620838096 LRP2/TGFBR3 2 GO:0061450 trophoblast cell migration 2/244 17/18722 0.0202248865218445 0.129297620838096 ITGB4/GJA1 2 GO:0022604 regulation of cell morphogenesis 9/244 309/18722 0.0204126003645074 0.130244281160721 EFNA5/KANK1/TACSTD2/CLDN4/DAG1/P4HB/MACF1/CUX1/MYH10 9 GO:0071901 negative regulation of protein serine/threonine kinase activity 5/244 120/18722 0.0205202232205369 0.130677235470318 LRP5/NR2F2/LATS2/BMP7/HYAL2 5 GO:0001570 vasculogenesis 4/244 80/18722 0.0205896520986999 0.130865757826553 ITGAV/ITGB8/TGFBR3/AMOT 4 GO:0035987 endodermal cell differentiation 3/244 45/18722 0.0207544761849679 0.131405026481319 LAMB1/ITGAV/MMP15 3 GO:0060119 inner ear receptor cell development 3/244 45/18722 0.0207544761849679 0.131405026481319 NAGLU/IFT27/TSKU 3 GO:0051098 regulation of binding 10/244 363/18722 0.0211173700121876 0.133445534346247 JUN/LRP1/ISL1/APP/CALM1/MET/DZIP1/TGFBR3/HOPX/FOXC1 10 GO:0050796 regulation of insulin secretion 6/244 165/18722 0.021247131226945 0.133495359869486 EFNA5/LRP5/LRP1/ISL1/DPP4/GJA1 6 GO:0071772 response to BMP 6/244 165/18722 0.021247131226945 0.133495359869486 LRP2/FBN1/SPINT1/BMP7/TGFBR3/DDX5 6 GO:0071773 cellular response to BMP stimulus 6/244 165/18722 0.021247131226945 0.133495359869486 LRP2/FBN1/SPINT1/BMP7/TGFBR3/DDX5 6 GO:0006457 protein folding 7/244 212/18722 0.0214133754671444 0.133965756069484 PDIA5/HSPA5/ERP29/P4HB/LMAN1/DNAJB14/PDIA3 7 GO:0048708 astrocyte differentiation 4/244 81/18722 0.0214443054450847 0.133965756069484 LRP1/IL6ST/APP/SERPINE2 4 GO:1903533 regulation of protein targeting 4/244 81/18722 0.0214443054450847 0.133965756069484 TCAF1/HUWE1/LMAN1/SREBF2 4 GO:0070588 calcium ion transmembrane transport 9/244 312/18722 0.0215693120829783 0.134491004752688 MCOLN3/ATP2B1/CALM1/AHNAK/ITGAV/P2RY6/ATP2B4/HTT/STIM1 9 GO:1902904 negative regulation of supramolecular fiber organization 6/244 166/18722 0.0218123698573373 0.135552248411827 SVIL/PPP1R9A/KANK1/TACSTD2/MET/SPTBN1 6 GO:0051928 positive regulation of calcium ion transport 5/244 122/18722 0.0218636125122157 0.135552248411827 ATP2B1/CALM1/P2RY6/HTT/STIM1 5 GO:0043583 ear development 7/244 213/18722 0.0219045173179185 0.135552248411827 LGR5/MCOLN3/NAGLU/ATP6V1B1/IFT27/GLI3/TSKU 7 GO:0051651 maintenance of location in cell 7/244 213/18722 0.0219045173179185 0.135552248411827 MCOLN3/CALM1/AKAP9/P2RY6/HSPA5/GJA1/HTT 7 GO:1900271 regulation of long-term synaptic potentiation 3/244 46/18722 0.0219938307338561 0.135849112389946 PPP1R9A/APP/LGMN 3 GO:0001892 embryonic placenta development 4/244 82/18722 0.0223204033313082 0.137281946605887 NR2F2/SPINT1/BMP7/KRT19 4 GO:1905897 regulation of response to endoplasmic reticulum stress 4/244 82/18722 0.0223204033313082 0.137281946605887 HSPA5/ERP29/USP25/SVIP 4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 6/244 167/18722 0.0223876875608855 0.137281946605887 PALLD/TENM3/ITGB1/DSC2/DSG2/CDH1 6 GO:0003231 cardiac ventricle development 5/244 123/18722 0.022556242785092 0.137281946605887 LRP2/ISL1/GJA5/TGFBR3/FOXC1 5 GO:0003128 heart field specification 2/244 18/18722 0.0225600277441202 0.137281946605887 LRP2/ISL1 2 GO:0021534 cell proliferation in hindbrain 2/244 18/18722 0.0225600277441202 0.137281946605887 SLC6A4/RERE 2 GO:0060973 cell migration involved in heart development 2/244 18/18722 0.0225600277441202 0.137281946605887 BMP7/FOLR1 2 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus 2/244 18/18722 0.0225600277441202 0.137281946605887 SEMA6A/ATP2B4 2 GO:0031669 cellular response to nutrient levels 7/244 215/18722 0.0229101493221633 0.139154807158278 JUN/TBL2/ATP2B1/CTSV/FOLR1/HSPA5/SREBF2 7 GO:0006816 calcium ion transport 11/244 422/18722 0.0229954558368236 0.13941525439078 MCOLN3/ATP2B1/KCNN4/CALM1/AHNAK/ITGAV/P2RY6/GJA1/ATP2B4/HTT/STIM1 11 GO:0010799 regulation of peptidyl-threonine phosphorylation 3/244 47/18722 0.0232727996718742 0.139806983037987 BMP7/APP/CALM1 3 GO:0019884 antigen processing and presentation of exogenous antigen 3/244 47/18722 0.0232727996718742 0.139806983037987 CTSL/CTSV/LGMN 3 GO:0042311 vasodilation 3/244 47/18722 0.0232727996718742 0.139806983037987 ADRB1/GJA5/GJA1 3 GO:0046677 response to antibiotic 3/244 47/18722 0.0232727996718742 0.139806983037987 HSPA5/HYAL2/SLC1A3 3 GO:0050885 neuromuscular process controlling balance 3/244 47/18722 0.0232727996718742 0.139806983037987 APP/IGDCC3/SLC1A3 3 GO:0009612 response to mechanical stimulus 7/244 216/18722 0.0234247463730035 0.140462986462937 JUN/DAG1/TMEM150C/GJA1/HTT/SERPINE2/SLC1A3 7 GO:0006937 regulation of muscle contraction 6/244 169/18722 0.0235688407063486 0.141069600293372 ATP2B1/CALM1/GJA5/AKAP9/DSC2/DSG2 6 GO:0007596 blood coagulation 7/244 217/18722 0.0239472676352732 0.143032483516699 F5/IL6ST/VCL/GNAQ/HPS6/LMAN1/SERPINE2 7 GO:1904375 regulation of protein localization to cell periphery 5/244 125/18722 0.0239838400540783 0.143032483516699 LRP1/DAG1/ITGB1/ATP2B4/SPTBN1 5 GO:0010921 regulation of phosphatase activity 4/244 84/18722 0.0241373913016532 0.143390679557868 SLC39A10/CALM1/RCAN1/HTT 4 GO:0042310 vasoconstriction 4/244 84/18722 0.0241373913016532 0.143390679557868 ATP2B1/SLC6A4/GJA5/GJA1 4 GO:0030178 negative regulation of Wnt signaling pathway 6/244 170/18722 0.0241748132912534 0.143390679557868 LRP1/ISL1/LATS2/TLE4/GLI3/TSKU 6 GO:0007163 establishment or maintenance of cell polarity 7/244 218/18722 0.0244777649126722 0.144926009915389 DST/KANK1/ITGB1/GJA1/WWC1/HTT/AMOT 7 GO:0006670 sphingosine metabolic process 2/244 19/18722 0.0250005399668022 0.146177534396641 ASAH1/PLPP3 2 GO:0007039 protein catabolic process in the vacuole 2/244 19/18722 0.0250005399668022 0.146177534396641 LRP2/LRP1 2 GO:0044003 modulation by symbiont of host process 2/244 19/18722 0.0250005399668022 0.146177534396641 DAG1/HYAL2 2 GO:0086014 atrial cardiac muscle cell action potential 2/244 19/18722 0.0250005399668022 0.146177534396641 GJA5/GJA1 2 GO:0086026 atrial cardiac muscle cell to AV node cell signaling 2/244 19/18722 0.0250005399668022 0.146177534396641 GJA5/GJA1 2 GO:0086066 atrial cardiac muscle cell to AV node cell communication 2/244 19/18722 0.0250005399668022 0.146177534396641 GJA5/GJA1 2 GO:2000738 positive regulation of stem cell differentiation 2/244 19/18722 0.0250005399668022 0.146177534396641 TACSTD2/FOXC1 2 GO:0060021 roof of mouth development 4/244 85/18722 0.0250784930914344 0.146372874419988 FRAS1/ITGB8/GLI3/TGFBR3 4 GO:1901136 carbohydrate derivative catabolic process 6/244 172/18722 0.0254178838324855 0.148090720343169 CTSL/MANBA/NAGLU/GNS/HYAL2/CST3 6 GO:0038084 vascular endothelial growth factor signaling pathway 3/244 49/18722 0.0259495188612861 0.150123448905257 NRP2/SEMA6A/FOXC1 3 GO:0045778 positive regulation of ossification 3/244 49/18722 0.0259495188612861 0.150123448905257 FBN2/ATP2B1/BMP7 3 GO:0046580 negative regulation of Ras protein signal transduction 3/244 49/18722 0.0259495188612861 0.150123448905257 KANK1/MET/ITGB1 3 GO:0070169 positive regulation of biomineral tissue development 3/244 49/18722 0.0259495188612861 0.150123448905257 FBN2/ATP2B1/BMP7 3 GO:0051099 positive regulation of binding 6/244 173/18722 0.0260551112618617 0.150302104165747 LRP1/ISL1/APP/CALM1/MET/FOXC1 6 GO:0072503 cellular divalent inorganic cation homeostasis 12/244 486/18722 0.0260852105990558 0.150302104165747 LRP1/MCOLN3/ATP2B1/SLC39A10/APP/CALM1/ITGAV/P2RY6/GJA1/ATP2B4/HTT/STIM1 12 GO:0008406 gonad development 7/244 221/18722 0.0261176206569207 0.150302104165747 LRP2/NR2F2/ADAMTS1/CTSV/HSPA5/SF1/FOXC1 7 GO:0007599 hemostasis 7/244 222/18722 0.026680526340189 0.152834877557335 F5/IL6ST/VCL/GNAQ/HPS6/LMAN1/SERPINE2 7 GO:0050817 coagulation 7/244 222/18722 0.026680526340189 0.152834877557335 F5/IL6ST/VCL/GNAQ/HPS6/LMAN1/SERPINE2 7 GO:0052548 regulation of endopeptidase activity 11/244 432/18722 0.026697267108311 0.152834877557335 APLP2/SPINT1/APP/ITIH5/GAPDH/CPAMD8/SERPINH1/DHCR24/LGMN/SERPINE2/CST3 11 GO:2000177 regulation of neural precursor cell proliferation 4/244 87/18722 0.0270263892091555 0.154186194882898 LRP2/SPINT1/SLC6A4/GLI3 4 GO:0060688 regulation of morphogenesis of a branching structure 3/244 50/18722 0.0273471834910996 0.154186194882898 TACSTD2/BMP7/LGR4 3 GO:0110151 positive regulation of biomineralization 3/244 50/18722 0.0273471834910996 0.154186194882898 FBN2/ATP2B1/BMP7 3 GO:1903747 regulation of establishment of protein localization to mitochondrion 3/244 50/18722 0.0273471834910996 0.154186194882898 HUWE1/LMAN1/SREBF2 3 GO:1905475 regulation of protein localization to membrane 6/244 175/18722 0.027361264289177 0.154186194882898 LRP1/TCAF1/DAG1/ITGB1/ATP2B4/SPTBN1 6 GO:0006346 DNA methylation-dependent heterochromatin assembly 2/244 20/18722 0.0275433038333113 0.154186194882898 MPHOSPH8/DNMT3A 2 GO:0007620 copulation 2/244 20/18722 0.0275433038333113 0.154186194882898 SLC6A4/SERPINE2 2 GO:0010042 response to manganese ion 2/244 20/18722 0.0275433038333113 0.154186194882898 APP/HSPA5 2 GO:0042359 vitamin D metabolic process 2/244 20/18722 0.0275433038333113 0.154186194882898 LRP2/LGMN 2 GO:0060044 negative regulation of cardiac muscle cell proliferation 2/244 20/18722 0.0275433038333113 0.154186194882898 JARID2/GJA1 2 GO:0071625 vocalization behavior 2/244 20/18722 0.0275433038333113 0.154186194882898 NLGN4X/GLI3 2 GO:1904292 regulation of ERAD pathway 2/244 20/18722 0.0275433038333113 0.154186194882898 USP25/SVIP 2 GO:2000479 regulation of cAMP-dependent protein kinase activity 2/244 20/18722 0.0275433038333113 0.154186194882898 ATP2B4/HTT 2 GO:0045785 positive regulation of cell adhesion 11/244 437/18722 0.0287019722348574 0.160313874807749 CCDC80/UTRN/IL6ST/BMP7/ITGAV/DAG1/P4HB/DPP4/GLI3/PLPP3/GCNT2 11 GO:0051293 establishment of spindle localization 3/244 51/18722 0.0287842927987132 0.160313874807749 ITGB1/GJA1/HTT 3 GO:0060043 regulation of cardiac muscle cell proliferation 3/244 51/18722 0.0287842927987132 0.160313874807749 JARID2/GJA1/TGFBR3 3 GO:0006486 protein glycosylation 7/244 226/18722 0.0290148680870016 0.160772975243047 GALNT11/MAN2A2/EXTL2/FUT8/TMTC3/RPN2/GCNT2 7 GO:0043413 macromolecule glycosylation 7/244 226/18722 0.0290148680870016 0.160772975243047 GALNT11/MAN2A2/EXTL2/FUT8/TMTC3/RPN2/GCNT2 7 GO:0014910 regulation of smooth muscle cell migration 4/244 89/18722 0.0290624307043122 0.160772975243047 LRP1/SEMA6D/ADAMTS1/P2RY6 4 GO:1900407 regulation of cellular response to oxidative stress 4/244 89/18722 0.0290624307043122 0.160772975243047 BMP7/MET/FUT8/P4HB 4 GO:0050804 modulation of chemical synaptic transmission 11/244 439/18722 0.0295334402013013 0.162604546884805 NLGN4X/PPP1R9A/SLC6A4/APP/CALM1/AKAP9/ITGB1/LGMN/CDH1/SERPINE2/SLC1A3 11 GO:0045137 development of primary sexual characteristics 7/244 227/18722 0.0296193656841864 0.162604546884805 LRP2/NR2F2/ADAMTS1/CTSV/HSPA5/SF1/FOXC1 7 GO:0099177 regulation of trans-synaptic signaling 11/244 440/18722 0.0299556000958559 0.162604546884805 NLGN4X/PPP1R9A/SLC6A4/APP/CALM1/AKAP9/ITGB1/LGMN/CDH1/SERPINE2/SLC1A3 11 GO:0042326 negative regulation of phosphorylation 10/244 385/18722 0.0300324341420348 0.162604546884805 LRP5/NR2F2/LRP1/LATS2/BMP7/CALM1/PLPP3/GNAQ/CTDSPL/HYAL2 10 GO:0006941 striated muscle contraction 6/244 179/18722 0.0301020363684692 0.162604546884805 CALM1/GJA5/AKAP9/DSC2/GJA1/DSG2 6 GO:0007626 locomotory behavior 6/244 179/18722 0.0301020363684692 0.162604546884805 MCOLN3/APP/NAGLU/DPP4/RCAN1/PUM1 6 GO:0002028 regulation of sodium ion transport 4/244 90/18722 0.0301136886108805 0.162604546884805 UTRN/ATP2B4/SERPINE2/MLLT6 4 GO:0035304 regulation of protein dephosphorylation 4/244 90/18722 0.0301136886108805 0.162604546884805 SLC39A10/CALM1/RCAN1/HTT 4 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 4/244 90/18722 0.0301136886108805 0.162604546884805 JUN/ADAMTS1/P2RY6/GJA1 4 GO:0003091 renal water homeostasis 2/244 21/18722 0.0301852628118476 0.162604546884805 ATP6V1B1/HYAL2 2 GO:0032516 positive regulation of phosphoprotein phosphatase activity 2/244 21/18722 0.0301852628118476 0.162604546884805 SLC39A10/CALM1 2 GO:0045056 transcytosis 2/244 21/18722 0.0301852628118476 0.162604546884805 LRP2/LRP1 2 GO:0046519 sphingoid metabolic process 2/244 21/18722 0.0301852628118476 0.162604546884805 ASAH1/PLPP3 2 GO:0050849 negative regulation of calcium-mediated signaling 2/244 21/18722 0.0301852628118476 0.162604546884805 RCAN1/ATP2B4 2 GO:0090189 regulation of branching involved in ureteric bud morphogenesis 2/244 21/18722 0.0301852628118476 0.162604546884805 TACSTD2/LGR4 2 GO:2000178 negative regulation of neural precursor cell proliferation 2/244 21/18722 0.0301852628118476 0.162604546884805 SPINT1/SLC6A4 2 GO:0072132 mesenchyme morphogenesis 3/244 52/18722 0.030260752692869 0.162744408099456 ISL1/BMP7/FOXC1 3 GO:0098661 inorganic anion transmembrane transport 4/244 91/18722 0.0311871885267243 0.167179610927922 SLC26A2/GABRE/SLC12A9/SLC1A3 4 GO:1990874 vascular associated smooth muscle cell proliferation 4/244 91/18722 0.0311871885267243 0.167179610927922 JUN/ADAMTS1/P2RY6/GJA1 4 GO:0008347 glial cell migration 3/244 53/18722 0.0317764498843511 0.169234058865442 LRP1/LAMB1/GLI3 3 GO:0031279 regulation of cyclase activity 3/244 53/18722 0.0317764498843511 0.169234058865442 CALM1/AKAP9/STIM1 3 GO:0071320 cellular response to cAMP 3/244 53/18722 0.0317764498843511 0.169234058865442 APP/AKAP9/HSPA5 3 GO:1990090 cellular response to nerve growth factor stimulus 3/244 53/18722 0.0317764498843511 0.169234058865442 APP/HSPA5/KIDINS220 3 GO:0042157 lipoprotein metabolic process 5/244 135/18722 0.031990095877137 0.170096205586201 LRP1/PGAP1/ITGAV/OLR1/SVIP 5 GO:0060401 cytosolic calcium ion transport 6/244 182/18722 0.0322717982055586 0.171316847986212 MCOLN3/ATP2B1/CALM1/P2RY6/ATP2B4/HTT 6 GO:0032271 regulation of protein polymerization 7/244 232/18722 0.0327695464694259 0.172271281873306 SVIL/PPP1R9A/KANK1/IQGAP2/MET/AKAP9/SPTBN1 7 GO:0042176 regulation of protein catabolic process 10/244 391/18722 0.0328677539969599 0.172271281873306 LRP2/LRP1/GJA1/HUWE1/TMTC3/CDH1/USP25/SERPINE2/SVIP/CST3 10 GO:0003158 endothelium development 5/244 136/18722 0.0328720551930901 0.172271281873306 NR2F2/MET/GJA5/VCL/GJA1 5 GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization 2/244 22/18722 0.0329234220987329 0.172271281873306 FOLR1/SPESP1 2 GO:0031061 negative regulation of histone methylation 2/244 22/18722 0.0329234220987329 0.172271281873306 JARID2/MLLT6 2 GO:0035809 regulation of urine volume 2/244 22/18722 0.0329234220987329 0.172271281873306 MLLT6/HYAL2 2 GO:0051412 response to corticosterone 2/244 22/18722 0.0329234220987329 0.172271281873306 ATP2B1/CALM1 2 GO:0060713 labyrinthine layer morphogenesis 2/244 22/18722 0.0329234220987329 0.172271281873306 SPINT1/BMP7 2 GO:0071404 cellular response to low-density lipoprotein particle stimulus 2/244 22/18722 0.0329234220987329 0.172271281873306 ITGB1/SREBF2 2 GO:0001706 endoderm formation 3/244 54/18722 0.0333312525883887 0.172754725560639 LAMB1/ITGAV/MMP15 3 GO:0010524 positive regulation of calcium ion transport into cytosol 3/244 54/18722 0.0333312525883887 0.172754725560639 CALM1/P2RY6/HTT 3 GO:0060350 endochondral bone morphogenesis 3/244 54/18722 0.0333312525883887 0.172754725560639 SERPINH1/FOXC1/TSKU 3 GO:0070839 metal ion export 3/244 54/18722 0.0333312525883887 0.172754725560639 ATP2B1/CALM1/ATP2B4 3 GO:0072348 sulfur compound transport 3/244 54/18722 0.0333312525883887 0.172754725560639 SLC26A2/SLC19A3/GJA1 3 GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II 3/244 54/18722 0.0333312525883887 0.172754725560639 JUN/TEAD1/SREBF2 3 GO:0006874 cellular calcium ion homeostasis 11/244 448/18722 0.0334898662983427 0.173030975874771 LRP1/MCOLN3/ATP2B1/APP/CALM1/ITGAV/P2RY6/GJA1/ATP2B4/HTT/STIM1 11 GO:0022407 regulation of cell-cell adhesion 11/244 448/18722 0.0334898662983427 0.173030975874771 EFNA5/IL6ST/TENM3/BMP7/MIA3/DPP4/GLI3/PLPP3/CDH1/SERPINE2/GCNT2 11 GO:0048562 embryonic organ morphogenesis 8/244 285/18722 0.0337354083654887 0.173112506736962 FBN1/FBN2/BMP7/NAGLU/ATP6V1B1/FOLR1/GLI3/EFEMP1 8 GO:0008203 cholesterol metabolic process 5/244 137/18722 0.0337690556355425 0.173112506736962 LRP5/APP/DHCR24/SREBF2/TSKU 5 GO:0010977 negative regulation of neuron projection development 5/244 137/18722 0.0337690556355425 0.173112506736962 LRP1/SEMA6A/SEMA6D/KANK1/TSKU 5 GO:0050684 regulation of mRNA processing 5/244 137/18722 0.0337690556355425 0.173112506736962 SON/SRSF2/SF1/DDX5/RBM25 5 GO:0060078 regulation of postsynaptic membrane potential 5/244 137/18722 0.0337690556355425 0.173112506736962 NLGN4X/PPP1R9A/ADRB1/APP/GABRE 5 GO:0051896 regulation of protein kinase B signaling 6/244 185/18722 0.0345409961117169 0.176248249365975 LRP2/MET/DAG1/ITGB1/GCNT2/HYAL2 6 GO:0014020 primary neural tube formation 4/244 94/18722 0.034541653253709 0.176248249365975 LRP2/SPINT1/BMP7/FOLR1 4 GO:1990830 cellular response to leukemia inhibitory factor 4/244 94/18722 0.034541653253709 0.176248249365975 NRP2/JARID2/TLE4/PCOLCE2 4 GO:0042220 response to cocaine 3/244 55/18722 0.0349250112097587 0.177928041605065 HSPA5/DNMT3A/SLC1A3 3 GO:0031345 negative regulation of cell projection organization 6/244 186/18722 0.0353197175865799 0.178285931737071 LRP1/SEMA6A/SEMA6D/KANK1/TACSTD2/TSKU 6 GO:0008585 female gonad development 4/244 95/18722 0.0357046013840121 0.178285931737071 NR2F2/ADAMTS1/HSPA5/FOXC1 4 GO:1990823 response to leukemia inhibitory factor 4/244 95/18722 0.0357046013840121 0.178285931737071 NRP2/JARID2/TLE4/PCOLCE2 4 GO:0003283 atrial septum development 2/244 23/18722 0.0357548475394796 0.178285931737071 ISL1/GJA5 2 GO:0018279 protein N-linked glycosylation via asparagine 2/244 23/18722 0.0357548475394796 0.178285931737071 FUT8/RPN2 2 GO:0019430 removal of superoxide radicals 2/244 23/18722 0.0357548475394796 0.178285931737071 BMP7/SOD3 2 GO:0021871 forebrain regionalization 2/244 23/18722 0.0357548475394796 0.178285931737071 PGAP1/GLI3 2 GO:0030539 male genitalia development 2/244 23/18722 0.0357548475394796 0.178285931737071 DHCR24/LGR4 2 GO:0034695 response to prostaglandin E 2/244 23/18722 0.0357548475394796 0.178285931737071 P2RY6/TGFBR3 2 GO:0035812 renal sodium excretion 2/244 23/18722 0.0357548475394796 0.178285931737071 ATP6V1B1/MLLT6 2 GO:0045724 positive regulation of cilium assembly 2/244 23/18722 0.0357548475394796 0.178285931737071 DZIP1/HTT 2 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization 2/244 23/18722 0.0357548475394796 0.178285931737071 GJA5/AKAP9 2 GO:0060384 innervation 2/244 23/18722 0.0357548475394796 0.178285931737071 ISL1/SERPINE2 2 GO:1900273 positive regulation of long-term synaptic potentiation 2/244 23/18722 0.0357548475394796 0.178285931737071 APP/LGMN 2 GO:0045765 regulation of angiogenesis 9/244 342/18722 0.0358369033855109 0.178424340189074 SEMA6A/ISL1/ADAMTS1/ITGB1/ITGB8/ATP2B4/STIM1/AMOT/FOXC1 9 GO:0015800 acidic amino acid transport 3/244 56/18722 0.0365575590109486 0.180102157286322 ITGB1/GJA1/SLC1A3 3 GO:0031122 cytoplasmic microtubule organization 3/244 56/18722 0.0365575590109486 0.180102157286322 DST/HOOK2/SLK 3 GO:0043388 positive regulation of DNA binding 3/244 56/18722 0.0365575590109486 0.180102157286322 ISL1/CALM1/FOXC1 3 GO:0051058 negative regulation of small GTPase mediated signal transduction 3/244 56/18722 0.0365575590109486 0.180102157286322 KANK1/MET/ITGB1 3 GO:0051653 spindle localization 3/244 56/18722 0.0365575590109486 0.180102157286322 ITGB1/GJA1/HTT 3 GO:0055078 sodium ion homeostasis 3/244 56/18722 0.0365575590109486 0.180102157286322 ATP6V1B1/MLLT6/SLC1A3 3 GO:1990089 response to nerve growth factor 3/244 56/18722 0.0365575590109486 0.180102157286322 APP/HSPA5/KIDINS220 3 GO:0055017 cardiac muscle tissue growth 4/244 96/18722 0.0368899990949255 0.181299347364376 JARID2/GJA1/TGFBR3/FOXC1 4 GO:0030308 negative regulation of cell growth 6/244 188/18722 0.0369109139947558 0.181299347364376 SEMA6A/SEMA6D/DCBLD2/GJA1/SERPINE2/HYAL2 6 GO:0010632 regulation of epithelial cell migration 8/244 292/18722 0.0380664089133944 0.18631474631551 NR2F2/NRP2/TACSTD2/MET/MACF1/ATP2B4/LGMN/PLPP3 8 GO:0014909 smooth muscle cell migration 4/244 97/18722 0.0380978686252237 0.18631474631551 LRP1/SEMA6D/ADAMTS1/P2RY6 4 GO:0070085 glycosylation 7/244 240/18722 0.0382624164440818 0.18631474631551 GALNT11/MAN2A2/EXTL2/FUT8/TMTC3/RPN2/GCNT2 7 GO:0097553 calcium ion transmembrane import into cytosol 5/244 142/18722 0.0384814703377575 0.18631474631551 MCOLN3/CALM1/P2RY6/ATP2B4/HTT 5 GO:0009755 hormone-mediated signaling pathway 6/244 190/18722 0.0385473958335837 0.18631474631551 LGR5/ISL1/LATS2/BMP7/LGR4/DDX5 6 GO:0001702 gastrulation with mouth forming second 2/244 24/18722 0.0386766645673149 0.18631474631551 LRP5/AMOT 2 GO:0010288 response to lead ion 2/244 24/18722 0.0386766645673149 0.18631474631551 APP/DNMT3A 2 GO:0016486 peptide hormone processing 2/244 24/18722 0.0386766645673149 0.18631474631551 CTSL/ENPEP 2 GO:0018196 peptidyl-asparagine modification 2/244 24/18722 0.0386766645673149 0.18631474631551 FUT8/RPN2 2 GO:0021801 cerebral cortex radial glia-guided migration 2/244 24/18722 0.0386766645673149 0.18631474631551 LAMB1/GLI3 2 GO:0022030 telencephalon glial cell migration 2/244 24/18722 0.0386766645673149 0.18631474631551 LAMB1/GLI3 2 GO:0031639 plasminogen activation 2/244 24/18722 0.0386766645673149 0.18631474631551 DHCR24/SERPINE2 2 GO:2001026 regulation of endothelial cell chemotaxis 2/244 24/18722 0.0386766645673149 0.18631474631551 MET/LGMN 2 GO:0006936 muscle contraction 9/244 347/18722 0.038725797849511 0.18631474631551 UTRN/ATP2B1/CALM1/GJA5/AKAP9/DSC2/GJA1/ATP2B4/DSG2 9 GO:0043087 regulation of GTPase activity 9/244 348/18722 0.0393220802694522 0.188111427181764 EFNA5/RGL3/ADRB1/SYDE2/IQGAP2/MET/ITGB1/DOCK9/AMOT 9 GO:1901342 regulation of vasculature development 9/244 348/18722 0.0393220802694522 0.188111427181764 SEMA6A/ISL1/ADAMTS1/ITGB1/ITGB8/ATP2B4/STIM1/AMOT/FOXC1 9 GO:0043502 regulation of muscle adaptation 4/244 98/18722 0.039328225950661 0.188111427181764 IL6ST/DAG1/JARID2/ATP2B4 4 GO:1902882 regulation of response to oxidative stress 4/244 98/18722 0.039328225950661 0.188111427181764 BMP7/MET/FUT8/P4HB 4 GO:0016358 dendrite development 7/244 243/18722 0.0404691382010878 0.193287192047637 PPP1R9A/BMP7/APP/ITGB1/KIDINS220/CUX1/RERE 7 GO:0060291 long-term synaptic potentiation 4/244 99/18722 0.0405810808571441 0.193475118395642 PPP1R9A/APP/LGMN/SERPINE2 4 GO:0050890 cognition 8/244 296/18722 0.0407018137206997 0.193475118395642 NLGN4X/JUN/SLC6A4/APP/ITGB1/RCAN1/LGMN/HTT 8 GO:0023061 signal release 11/244 463/18722 0.0408963438514319 0.193475118395642 EFNA5/LRP5/LRP1/PPP1R9A/ISL1/SLC6A4/CALM1/WLS/DPP4/GJA1/RAB11FIP1 11 GO:0006898 receptor-mediated endocytosis 7/244 244/18722 0.0412227879103649 0.193475118395642 LRP2/LRP1/CTSL/ITGAV/ITGB1/FOLR1/AAK1 7 GO:0061351 neural precursor cell proliferation 5/244 145/18722 0.0414924419286962 0.193475118395642 LRP2/SPINT1/SLC6A4/RERE/GLI3 5 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 2/244 25/18722 0.0416860571588906 0.193475118395642 GJA5/GJA1 2 GO:0003094 glomerular filtration 2/244 25/18722 0.0416860571588906 0.193475118395642 GJA5/GJA1 2 GO:0010996 response to auditory stimulus 2/244 25/18722 0.0416860571588906 0.193475118395642 HTT/SLC1A3 2 GO:0030318 melanocyte differentiation 2/244 25/18722 0.0416860571588906 0.193475118395642 GLI3/HPS6 2 GO:0048143 astrocyte activation 2/244 25/18722 0.0416860571588906 0.193475118395642 LRP1/APP 2 GO:0060706 cell differentiation involved in embryonic placenta development 2/244 25/18722 0.0416860571588906 0.193475118395642 NR2F2/KRT19 2 GO:0061436 establishment of skin barrier 2/244 25/18722 0.0416860571588906 0.193475118395642 CLDN4/MET 2 GO:0062009 secondary palate development 2/244 25/18722 0.0416860571588906 0.193475118395642 ITGB8/TGFBR3 2 GO:0071450 cellular response to oxygen radical 2/244 25/18722 0.0416860571588906 0.193475118395642 BMP7/SOD3 2 GO:0071451 cellular response to superoxide 2/244 25/18722 0.0416860571588906 0.193475118395642 BMP7/SOD3 2 GO:0090330 regulation of platelet aggregation 2/244 25/18722 0.0416860571588906 0.193475118395642 IL6ST/SERPINE2 2 GO:0140448 signaling receptor ligand precursor processing 2/244 25/18722 0.0416860571588906 0.193475118395642 CTSL/ENPEP 2 GO:1903959 regulation of anion transmembrane transport 2/244 25/18722 0.0416860571588906 0.193475118395642 TCAF1/ITGB1 2 GO:1904754 positive regulation of vascular associated smooth muscle cell migration 2/244 25/18722 0.0416860571588906 0.193475118395642 LRP1/ADAMTS1 2 GO:1905048 regulation of metallopeptidase activity 2/244 25/18722 0.0416860571588906 0.193475118395642 LRP1/CLDN4 2 GO:0046545 development of primary female sexual characteristics 4/244 100/18722 0.0418564370155471 0.193991892853438 NR2F2/ADAMTS1/HSPA5/FOXC1 4 GO:0006814 sodium ion transport 7/244 245/18722 0.04198552714345 0.194316115765319 UTRN/SLC6A4/ATP6V1B1/ATP2B4/MAGED2/SERPINE2/MLLT6 7 GO:0051480 regulation of cytosolic calcium ion concentration 9/244 353/18722 0.0423973226989456 0.195719081958794 LRP1/MCOLN3/ATP2B1/CALM1/ITGAV/P2RY6/GJA1/ATP2B4/HTT 9 GO:0007043 cell-cell junction assembly 5/244 146/18722 0.0425269094700483 0.195719081958794 POF1B/CLDN4/GJA5/VCL/GJA1 5 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 5/244 146/18722 0.0425269094700483 0.195719081958794 LGR5/ADRB1/ATP2B4/LGR4/GNAQ 5 GO:0048813 dendrite morphogenesis 5/244 146/18722 0.0425269094700483 0.195719081958794 PPP1R9A/ITGB1/KIDINS220/CUX1/RERE 5 GO:0031668 cellular response to extracellular stimulus 7/244 246/18722 0.0427573855603963 0.196230124233886 JUN/TBL2/ATP2B1/CTSV/FOLR1/HSPA5/SREBF2 7 GO:0051402 neuron apoptotic process 7/244 246/18722 0.0427573855603963 0.196230124233886 JUN/LRP1/ISL1/APP/GAPDH/HSPA5/LGMN 7 GO:0030073 insulin secretion 6/244 195/18722 0.0428387426285247 0.196329300247325 EFNA5/LRP5/LRP1/ISL1/DPP4/GJA1 6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 3/244 60/18722 0.0434717433194495 0.198603982797529 SRSF2/DDX5/RBM25 3 GO:0042306 regulation of protein import into nucleus 3/244 60/18722 0.0434717433194495 0.198603982797529 GLI3/CDH1/HYAL2 3 GO:0016331 morphogenesis of embryonic epithelium 5/244 147/18722 0.0435768325006143 0.198603982797529 LRP2/SPINT1/BMP7/FOLR1/LAMA5 5 GO:1902652 secondary alcohol metabolic process 5/244 147/18722 0.0435768325006143 0.198603982797529 LRP5/APP/DHCR24/SREBF2/TSKU 5 GO:0031032 actomyosin structure organization 6/244 196/18722 0.0437316000236909 0.198758005086927 PPP1R9A/TACSTD2/MET/ITGB1/MYH10/KRT19 6 GO:0090276 regulation of peptide hormone secretion 6/244 196/18722 0.0437316000236909 0.198758005086927 EFNA5/LRP5/LRP1/ISL1/DPP4/GJA1 6 GO:0001841 neural tube formation 4/244 102/18722 0.0444746376560229 0.200201301670094 LRP2/SPINT1/BMP7/FOLR1 4 GO:0051051 negative regulation of transport 11/244 470/18722 0.0447150690518175 0.200201301670094 PPP1R9A/CALM1/ITGAV/ERP29/GABRE/GJA1/LMAN1/SREBF2/SERPINE2/SVIP/RAB11FIP1 11 GO:0002026 regulation of the force of heart contraction 2/244 26/18722 0.044780266806914 0.200201301670094 ADRB1/ATP2B4 2 GO:0034114 regulation of heterotypic cell-cell adhesion 2/244 26/18722 0.044780266806914 0.200201301670094 BMP7/GCNT2 2 GO:0045026 plasma membrane fusion 2/244 26/18722 0.044780266806914 0.200201301670094 FOLR1/SPESP1 2 GO:0046697 decidualization 2/244 26/18722 0.044780266806914 0.200201301670094 CTSV/GJA1 2 GO:0048668 collateral sprouting 2/244 26/18722 0.044780266806914 0.200201301670094 LRP1/APP 2 GO:0048843 negative regulation of axon extension involved in axon guidance 2/244 26/18722 0.044780266806914 0.200201301670094 SEMA6A/SEMA6D 2 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 2/244 26/18722 0.044780266806914 0.200201301670094 SLC39A10/KCNN4 2 GO:0060669 embryonic placenta morphogenesis 2/244 26/18722 0.044780266806914 0.200201301670094 SPINT1/BMP7 2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway 2/244 26/18722 0.044780266806914 0.200201301670094 ADRB1/ATP2B4 2 GO:0097205 renal filtration 2/244 26/18722 0.044780266806914 0.200201301670094 GJA5/GJA1 2 GO:0032956 regulation of actin cytoskeleton organization 9/244 357/18722 0.0449714610408761 0.20078290894065 SVIL/EFNA5/LRP1/PPP1R9A/KANK1/TACSTD2/IQGAP2/MET/SPTBN1 9 GO:0046883 regulation of hormone secretion 7/244 249/18722 0.0451279592205525 0.201208241517959 EFNA5/LRP5/LRP1/ISL1/DPP4/GJA1/RAB11FIP1 7 GO:0030199 collagen fibril organization 3/244 61/18722 0.0452951806867308 0.201407258100944 COL14A1/SERPINH1/FOXC1 3 GO:0040014 regulation of multicellular organism growth 3/244 61/18722 0.0452951806867308 0.201407258100944 ADRB1/APP/LGMN 3 GO:0016525 negative regulation of angiogenesis 5/244 149/18722 0.0457231462777199 0.203035484687281 SEMA6A/ADAMTS1/ATP2B4/AMOT/FOXC1 5 GO:0071900 regulation of protein serine/threonine kinase activity 9/244 359/18722 0.0462969805752413 0.205306178367399 LRP5/NR2F2/LATS2/BMP7/CALM1/ERP29/ATP2B4/HTT/HYAL2 9 GO:0046824 positive regulation of nucleocytoplasmic transport 3/244 62/18722 0.0471560821903876 0.207553516275563 GLI3/CDH1/HYAL2 3 GO:0048002 antigen processing and presentation of peptide antigen 3/244 62/18722 0.0471560821903876 0.207553516275563 CTSL/CTSV/LGMN 3 GO:0060135 maternal process involved in female pregnancy 3/244 62/18722 0.0471560821903876 0.207553516275563 NR2F2/CTSV/GJA1 3 GO:0048661 positive regulation of smooth muscle cell proliferation 4/244 104/18722 0.0471827378751812 0.207553516275563 JUN/ADAMTS1/P2RY6/GJA1 4 GO:0060419 heart growth 4/244 104/18722 0.0471827378751812 0.207553516275563 JARID2/GJA1/TGFBR3/FOXC1 4 GO:1903076 regulation of protein localization to plasma membrane 4/244 104/18722 0.0471827378751812 0.207553516275563 LRP1/ITGB1/ATP2B4/SPTBN1 4 GO:0002791 regulation of peptide secretion 6/244 200/18722 0.0474193319716187 0.208170884676376 EFNA5/LRP5/LRP1/ISL1/DPP4/GJA1 6 GO:0071456 cellular response to hypoxia 5/244 151/18722 0.0479315580509394 0.208170884676376 TBL2/MALAT1/BMP7/P4HB/DNMT3A 5 GO:2000181 negative regulation of blood vessel morphogenesis 5/244 151/18722 0.0479315580509394 0.208170884676376 SEMA6A/ADAMTS1/ATP2B4/AMOT/FOXC1 5 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 2/244 27/18722 0.0479565915094389 0.208170884676376 APP/PBX1 2 GO:0015813 L-glutamate transmembrane transport 2/244 27/18722 0.0479565915094389 0.208170884676376 ITGB1/SLC1A3 2 GO:0018126 protein hydroxylation 2/244 27/18722 0.0479565915094389 0.208170884676376 P3H2/P4HB 2 GO:0033561 regulation of water loss via skin 2/244 27/18722 0.0479565915094389 0.208170884676376 CLDN4/MET 2 GO:0033688 regulation of osteoblast proliferation 2/244 27/18722 0.0479565915094389 0.208170884676376 LRP5/ITGAV 2 GO:0034698 response to gonadotropin 2/244 27/18722 0.0479565915094389 0.208170884676376 CTSV/TGFBR3 2 GO:0099625 ventricular cardiac muscle cell membrane repolarization 2/244 27/18722 0.0479565915094389 0.208170884676376 GJA5/AKAP9 2 GO:0097305 response to alcohol 7/244 253/18722 0.0484180362621261 0.209896658518927 ATP2B1/CALM1/DAG1/P2RY6/CDH1/TGFBR3/DNMT3A 7 GO:1904589 regulation of protein import 3/244 63/18722 0.0490541784545382 0.211282018872306 GLI3/CDH1/HYAL2 3 GO:0016125 sterol metabolic process 5/244 152/18722 0.0490590932439346 0.211282018872306 LRP5/APP/DHCR24/SREBF2/TSKU 5 GO:0021915 neural tube development 5/244 152/18722 0.0490590932439346 0.211282018872306 LRP2/SPINT1/BMP7/FOLR1/GLI3 5 GO:0030509 BMP signaling pathway 5/244 152/18722 0.0490590932439346 0.211282018872306 LRP2/FBN1/BMP7/TGFBR3/DDX5 5 GO:1901343 negative regulation of vasculature development 5/244 152/18722 0.0490590932439346 0.211282018872306 SEMA6A/ADAMTS1/ATP2B4/AMOT/FOXC1 5 GO:0090087 regulation of peptide transport 6/244 202/18722 0.0493333401395076 0.212185020547673 EFNA5/LRP5/LRP1/ISL1/DPP4/GJA1 6 GO:0002062 chondrocyte differentiation 4/244 106/18722 0.0499805548636777 0.214687716708555 SERPINH1/GLI3/EFEMP1/TSKU 4 GO:0051924 regulation of calcium ion transport 7/244 255/18722 0.0501189273891731 0.215001038382275 ATP2B1/CALM1/AHNAK/P2RY6/GJA1/HTT/STIM1 7 GO:0030837 negative regulation of actin filament polymerization 3/244 64/18722 0.0509891877372444 0.216871888428509 SVIL/KANK1/SPTBN1 3 GO:0045995 regulation of embryonic development 3/244 64/18722 0.0509891877372444 0.216871888428509 DAG1/LAMA5/AMOT 3 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 3/244 64/18722 0.0509891877372444 0.216871888428509 EFNA5/LRP5/LRP1 3 GO:0000303 response to superoxide 2/244 28/18722 0.0512123847755606 0.216871888428509 BMP7/SOD3 2 GO:0001945 lymph vessel development 2/244 28/18722 0.0512123847755606 0.216871888428509 NR2F2/FOXC1 2 GO:0010575 positive regulation of vascular endothelial growth factor production 2/244 28/18722 0.0512123847755606 0.216871888428509 IL6ST/ISL1 2 GO:0051503 adenine nucleotide transport 2/244 28/18722 0.0512123847755606 0.216871888428509 GJA1/SLC19A1 2 GO:0099623 regulation of cardiac muscle cell membrane repolarization 2/244 28/18722 0.0512123847755606 0.216871888428509 GJA5/AKAP9 2 GO:0010927 cellular component assembly involved in morphogenesis 4/244 107/18722 0.0514130252847864 0.216871888428509 ITGB4/DAG1/ITGB1/KRT19 4 GO:0021761 limbic system development 4/244 107/18722 0.0514130252847864 0.216871888428509 NRP2/ATP2B4/GLI3/TSKU 4 GO:0036503 ERAD pathway 4/244 107/18722 0.0514130252847864 0.216871888428509 HSPA5/USP25/SVIP/DNAJB14 4 GO:0042303 molting cycle 4/244 107/18722 0.0514130252847864 0.216871888428509 LGR5/LAMA5/LGR4/TSKU 4 GO:0042633 hair cycle 4/244 107/18722 0.0514130252847864 0.216871888428509 LGR5/LAMA5/LGR4/TSKU 4 GO:0010970 transport along microtubule 5/244 155/18722 0.0525351547245875 0.221321177467942 ARMCX3/DST/APP/IFT27/HTT 5 GO:0060389 pathway-restricted SMAD protein phosphorylation 3/244 65/18722 0.0529608164612497 0.222543788864024 LRP1/BMP7/TGFBR3 3 GO:1902475 L-alpha-amino acid transmembrane transport 3/244 65/18722 0.0529608164612497 0.222543788864024 ITGB1/SLC38A9/SLC1A3 3 GO:0009267 cellular response to starvation 5/244 156/18722 0.0537250165704945 0.225169660264941 JUN/TBL2/CTSV/HSPA5/SREBF2 5 GO:0035051 cardiocyte differentiation 5/244 156/18722 0.0537250165704945 0.225169660264941 ISL1/BMP7/ITGB1/FOLR1/TGFBR3 5 GO:0043254 regulation of protein-containing complex assembly 10/244 427/18722 0.0538884743585646 0.225169660264941 SVIL/PPP1R9A/ISL1/KANK1/IQGAP2/MET/AKAP9/HSPA5/SPTBN1/SVIP 10 GO:0060249 anatomical structure homeostasis 8/244 314/18722 0.0540559651232718 0.225169660264941 LAMC1/ATP2B1/ITGB1/VCL/GJA1/ARMS2/GCNT2/FOXC1 8 GO:0000305 response to oxygen radical 2/244 29/18722 0.0545450546472591 0.225169660264941 BMP7/SOD3 2 GO:0015868 purine ribonucleotide transport 2/244 29/18722 0.0545450546472591 0.225169660264941 GJA1/SLC19A1 2 GO:0021522 spinal cord motor neuron differentiation 2/244 29/18722 0.0545450546472591 0.225169660264941 ISL1/GLI3 2 GO:0021591 ventricular system development 2/244 29/18722 0.0545450546472591 0.225169660264941 SEMA6D/TSKU 2 GO:0021602 cranial nerve morphogenesis 2/244 29/18722 0.0545450546472591 0.225169660264941 NRP2/GLI3 2 GO:0022011 myelination in peripheral nervous system 2/244 29/18722 0.0545450546472591 0.225169660264941 ITGB4/DAG1 2 GO:0032292 peripheral nervous system axon ensheathment 2/244 29/18722 0.0545450546472591 0.225169660264941 ITGB4/DAG1 2 GO:0034311 diol metabolic process 2/244 29/18722 0.0545450546472591 0.225169660264941 ASAH1/PLPP3 2 GO:0048665 neuron fate specification 2/244 29/18722 0.0545450546472591 0.225169660264941 ISL1/GLI3 2 GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus 2/244 29/18722 0.0545450546472591 0.225169660264941 SEMA6A/ATP2B4 2 GO:0019229 regulation of vasoconstriction 3/244 66/18722 0.054968759731007 0.226066764050174 ATP2B1/GJA5/GJA1 3 GO:0045600 positive regulation of fat cell differentiation 3/244 66/18722 0.054968759731007 0.226066764050174 LRP5/BMP7/CDS1 3 GO:0050922 negative regulation of chemotaxis 3/244 66/18722 0.054968759731007 0.226066764050174 SEMA6A/SEMA6D/DPP4 3 GO:0014812 muscle cell migration 4/244 110/18722 0.0558441596627472 0.229379885814734 LRP1/SEMA6D/ADAMTS1/P2RY6 4 GO:0010038 response to metal ion 9/244 373/18722 0.056307407326793 0.230993933178329 JUN/APP/CALM1/SOD3/HSPA5/LGMN/STIM1/CDH1/DNMT3A 9 GO:0009101 glycoprotein biosynthetic process 8/244 317/18722 0.0565251076638416 0.231597885016688 GALNT11/ITM2B/MAN2A2/EXTL2/FUT8/TMTC3/RPN2/GCNT2 8 GO:0009880 embryonic pattern specification 3/244 67/18722 0.0570127018362867 0.232725140663401 NRP2/BMP7/PGAP1 3 GO:0010517 regulation of phospholipase activity 3/244 67/18722 0.0570127018362867 0.232725140663401 LRP1/P2RY6/GNAQ 3 GO:0070527 platelet aggregation 3/244 67/18722 0.0570127018362867 0.232725140663401 IL6ST/VCL/SERPINE2 3 GO:0090288 negative regulation of cellular response to growth factor stimulus 4/244 111/18722 0.0573656020035472 0.233657028410132 LRP2/FBN1/SEMA6A/ATP2B4 4 GO:1903169 regulation of calcium ion transmembrane transport 5/244 159/18722 0.0573881465722895 0.233657028410132 CALM1/AHNAK/P2RY6/HTT/STIM1 5 GO:0006884 cell volume homeostasis 2/244 30/18722 0.0579520627371448 0.233657028410132 KCNN4/SLC12A9 2 GO:0007202 activation of phospholipase C activity 2/244 30/18722 0.0579520627371448 0.233657028410132 P2RY6/GNAQ 2 GO:0015865 purine nucleotide transport 2/244 30/18722 0.0579520627371448 0.233657028410132 GJA1/SLC19A1 2 GO:0034694 response to prostaglandin 2/244 30/18722 0.0579520627371448 0.233657028410132 P2RY6/TGFBR3 2 GO:0060351 cartilage development involved in endochondral bone morphogenesis 2/244 30/18722 0.0579520627371448 0.233657028410132 SERPINH1/TSKU 2 GO:0140058 neuron projection arborization 2/244 30/18722 0.0579520627371448 0.233657028410132 LRP2/MACF1 2 GO:1902751 positive regulation of cell cycle G2/M phase transition 2/244 30/18722 0.0579520627371448 0.233657028410132 APP/PBX1 2 GO:1903019 negative regulation of glycoprotein metabolic process 2/244 30/18722 0.0579520627371448 0.233657028410132 ITM2B/CST3 2 GO:0007204 positive regulation of cytosolic calcium ion concentration 8/244 319/18722 0.0582105143344946 0.234411458459742 LRP1/MCOLN3/CALM1/ITGAV/P2RY6/GJA1/ATP2B4/HTT 8 GO:0009896 positive regulation of catabolic process 11/244 492/18722 0.0582931921474832 0.234457073924884 LRP2/LRP1/KCNQ1OT1/APP/TNRC6B/GJA1/HUWE1/HTT/TMTC3/PUM1/SVIP 11 GO:0043491 protein kinase B signaling 6/244 211/18722 0.0585299393150995 0.235121492163101 LRP2/MET/DAG1/ITGB1/GCNT2/HYAL2 6 GO:0060402 calcium ion transport into cytosol 5/244 160/18722 0.0586403585896039 0.235277433852794 MCOLN3/CALM1/P2RY6/ATP2B4/HTT 5 GO:0006469 negative regulation of protein kinase activity 6/244 212/18722 0.0596110042815448 0.238589232727352 LRP5/NR2F2/LATS2/BMP7/GNAQ/HYAL2 6 GO:0009749 response to glucose 6/244 212/18722 0.0596110042815448 0.238589232727352 EFNA5/LRP5/LRP1/LDHA/CTSV/GJA1 6 GO:0036294 cellular response to decreased oxygen levels 5/244 161/18722 0.0599081420011644 0.239486806101978 TBL2/MALAT1/BMP7/P4HB/DNMT3A 5 GO:0010611 regulation of cardiac muscle hypertrophy 3/244 69/18722 0.0612072685690673 0.240598347919173 IL6ST/JARID2/ATP2B4 3 GO:0015807 L-amino acid transport 3/244 69/18722 0.0612072685690673 0.240598347919173 ITGB1/SLC38A9/SLC1A3 3 GO:0033344 cholesterol efflux 3/244 69/18722 0.0612072685690673 0.240598347919173 LRP1/SREBF2/TSKU 3 GO:0050805 negative regulation of synaptic transmission 3/244 69/18722 0.0612072685690673 0.240598347919173 NLGN4X/PPP1R9A/SLC6A4 3 GO:0002063 chondrocyte development 2/244 31/18722 0.0614309232818582 0.240598347919173 SERPINH1/TSKU 2 GO:0030212 hyaluronan metabolic process 2/244 31/18722 0.0614309232818582 0.240598347919173 ITIH5/HYAL2 2 GO:0043171 peptide catabolic process 2/244 31/18722 0.0614309232818582 0.240598347919173 ENPEP/CPQ 2 GO:0048710 regulation of astrocyte differentiation 2/244 31/18722 0.0614309232818582 0.240598347919173 IL6ST/SERPINE2 2 GO:0055022 negative regulation of cardiac muscle tissue growth 2/244 31/18722 0.0614309232818582 0.240598347919173 JARID2/GJA1 2 GO:0055075 potassium ion homeostasis 2/244 31/18722 0.0614309232818582 0.240598347919173 ATP6V1B1/SLC12A9 2 GO:0060390 regulation of SMAD protein signal transduction 2/244 31/18722 0.0614309232818582 0.240598347919173 LRP1/SPTBN1 2 GO:0061117 negative regulation of heart growth 2/244 31/18722 0.0614309232818582 0.240598347919173 JARID2/GJA1 2 GO:0070633 transepithelial transport 2/244 31/18722 0.0614309232818582 0.240598347919173 P2RY6/SLC1A3 2 GO:0090183 regulation of kidney development 2/244 31/18722 0.0614309232818582 0.240598347919173 TACSTD2/LGR4 2 GO:1900027 regulation of ruffle assembly 2/244 31/18722 0.0614309232818582 0.240598347919173 KANK1/TACSTD2 2 GO:1905144 response to acetylcholine 2/244 31/18722 0.0614309232818582 0.240598347919173 ATP2B4/GNAQ 2 GO:1905145 cellular response to acetylcholine 2/244 31/18722 0.0614309232818582 0.240598347919173 ATP2B4/GNAQ 2 GO:0001894 tissue homeostasis 7/244 268/18722 0.0620940726060432 0.242906098313641 LAMC1/ITGB1/VCL/GJA1/ARMS2/GCNT2/FOXC1 7 GO:0061025 membrane fusion 5/244 163/18722 0.0624903738158562 0.244165717430325 CTSL/FOLR1/HUWE1/SPESP1/HYAL2 5 GO:0003407 neural retina development 3/244 70/18722 0.0633572120529544 0.246965360386724 ATP2B1/NAGLU/ATP2B4 3 GO:0070830 bicellular tight junction assembly 3/244 70/18722 0.0633572120529544 0.246965360386724 POF1B/CLDN4/GJA1 3 GO:1902903 regulation of supramolecular fiber organization 9/244 382/18722 0.063432558127209 0.246966097163517 SVIL/PPP1R9A/KANK1/TACSTD2/APP/IQGAP2/MET/AKAP9/SPTBN1 9 GO:0030278 regulation of ossification 4/244 115/18722 0.0636716360704257 0.247310870126973 FBN2/ATP2B1/BMP7/PBX1 4 GO:0051209 release of sequestered calcium ion into cytosol 4/244 115/18722 0.0636716360704257 0.247310870126973 MCOLN3/CALM1/P2RY6/HTT 4 GO:0050806 positive regulation of synaptic transmission 5/244 164/18722 0.0638047912312683 0.247535471057789 PPP1R9A/APP/LGMN/SERPINE2/SLC1A3 5 GO:0045936 negative regulation of phosphate metabolic process 10/244 441/18722 0.0640382798263963 0.247704940214572 LRP5/NR2F2/LRP1/LATS2/BMP7/CALM1/PLPP3/GNAQ/CTDSPL/HYAL2 10 GO:0010563 negative regulation of phosphorus metabolic process 10/244 442/18722 0.0648073863604832 0.247704940214572 LRP5/NR2F2/LRP1/LATS2/BMP7/CALM1/PLPP3/GNAQ/CTDSPL/HYAL2 10 GO:0003338 metanephros morphogenesis 2/244 32/18722 0.0649792022108829 0.247704940214572 FRAS1/LGR4 2 GO:0009954 proximal/distal pattern formation 2/244 32/18722 0.0649792022108829 0.247704940214572 PBX1/GLI3 2 GO:0014044 Schwann cell development 2/244 32/18722 0.0649792022108829 0.247704940214572 ITGB4/DAG1 2 GO:0021799 cerebral cortex radially oriented cell migration 2/244 32/18722 0.0649792022108829 0.247704940214572 LAMB1/GLI3 2 GO:0033687 osteoblast proliferation 2/244 32/18722 0.0649792022108829 0.247704940214572 LRP5/ITGAV 2 GO:0035767 endothelial cell chemotaxis 2/244 32/18722 0.0649792022108829 0.247704940214572 MET/LGMN 2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity 2/244 32/18722 0.0649792022108829 0.247704940214572 NR2F2/LATS2 2 GO:0045761 regulation of adenylate cyclase activity 2/244 32/18722 0.0649792022108829 0.247704940214572 AKAP9/STIM1 2 GO:0045879 negative regulation of smoothened signaling pathway 2/244 32/18722 0.0649792022108829 0.247704940214572 GLI3/SERPINE2 2 GO:0048841 regulation of axon extension involved in axon guidance 2/244 32/18722 0.0649792022108829 0.247704940214572 SEMA6A/SEMA6D 2 GO:0051642 centrosome localization 2/244 32/18722 0.0649792022108829 0.247704940214572 AKAP9/SYNE2 2 GO:0071875 adrenergic receptor signaling pathway 2/244 32/18722 0.0649792022108829 0.247704940214572 ADRB1/ATP2B4 2 GO:1903955 positive regulation of protein targeting to mitochondrion 2/244 32/18722 0.0649792022108829 0.247704940214572 HUWE1/SREBF2 2 GO:0046661 male sex differentiation 5/244 165/18722 0.0651347181064033 0.248010062222064 LRP2/CTSV/DHCR24/LGR4/SF1 5 GO:0021782 glial cell development 4/244 116/18722 0.0653028318383494 0.248075266382446 ITGB4/LRP1/APP/DAG1 4 GO:0051283 negative regulation of sequestering of calcium ion 4/244 116/18722 0.0653028318383494 0.248075266382446 MCOLN3/CALM1/P2RY6/HTT 4 GO:0000281 mitotic cytokinesis 3/244 71/18722 0.0655417930028993 0.248408687205914 SON/SPTBN1/MYH10 3 GO:0003281 ventricular septum development 3/244 71/18722 0.0655417930028993 0.248408687205914 LRP2/GJA5/TGFBR3 3 GO:0060538 skeletal muscle organ development 5/244 166/18722 0.0664801326482998 0.251674787882849 SVIL/NR2F2/DAG1/RCAN1/DDX5 5 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 7/244 273/18722 0.0671282550388767 0.253835956338031 PALLD/TENM3/CLDN4/ITGB1/DSC2/DSG2/CDH1 7 GO:0009746 response to hexose 6/244 219/18722 0.0675111499118604 0.254990389207326 EFNA5/LRP5/LRP1/LDHA/CTSV/GJA1 6 GO:0014743 regulation of muscle hypertrophy 3/244 72/18722 0.0677606487393384 0.255035442889112 IL6ST/JARID2/ATP2B4 3 GO:0042246 tissue regeneration 3/244 72/18722 0.0677606487393384 0.255035442889112 DAG1/CPQ/HOPX 3 GO:0055021 regulation of cardiac muscle tissue growth 3/244 72/18722 0.0677606487393384 0.255035442889112 JARID2/GJA1/TGFBR3 3 GO:0010259 multicellular organism aging 2/244 33/18722 0.0685945162305323 0.255035442889112 CTSV/HYAL2 2 GO:0031116 positive regulation of microtubule polymerization 2/244 33/18722 0.0685945162305323 0.255035442889112 MET/AKAP9 2 GO:0034110 regulation of homotypic cell-cell adhesion 2/244 33/18722 0.0685945162305323 0.255035442889112 IL6ST/SERPINE2 2 GO:0060122 inner ear receptor cell stereocilium organization 2/244 33/18722 0.0685945162305323 0.255035442889112 IFT27/TSKU 2 GO:0061842 microtubule organizing center localization 2/244 33/18722 0.0685945162305323 0.255035442889112 AKAP9/SYNE2 2 GO:0071295 cellular response to vitamin 2/244 33/18722 0.0685945162305323 0.255035442889112 ATP2B1/FOLR1 2 GO:0120033 negative regulation of plasma membrane bounded cell projection assembly 2/244 33/18722 0.0685945162305323 0.255035442889112 KANK1/TACSTD2 2 GO:1903146 regulation of autophagy of mitochondrion 2/244 33/18722 0.0685945162305323 0.255035442889112 HTT/SREBF2 2 GO:1904030 negative regulation of cyclin-dependent protein kinase activity 2/244 33/18722 0.0685945162305323 0.255035442889112 NR2F2/LATS2 2 GO:0051101 regulation of DNA binding 4/244 118/18722 0.0686302508063641 0.255035442889112 JUN/ISL1/CALM1/FOXC1 4 GO:0051282 regulation of sequestering of calcium ion 4/244 118/18722 0.0686302508063641 0.255035442889112 MCOLN3/CALM1/P2RY6/HTT 4 GO:0002064 epithelial cell development 6/244 220/18722 0.0686872693112795 0.255035442889112 ADAMTSL4/POF1B/IL6ST/PALLD/MET/VCL 6 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 3/244 73/18722 0.0700134085234455 0.259665982401853 EFNA5/LRP5/LRP1 3 GO:0030282 bone mineralization 4/244 119/18722 0.070326284922921 0.260532324979389 FBN2/ATP2B1/BMP7/LGR4 4 GO:0021543 pallium development 5/244 169/18722 0.0706090472659249 0.260991371558863 LRP1/LAMB1/ATP2B4/GLI3/TSKU 5 GO:0031214 biomineral tissue development 5/244 169/18722 0.0706090472659249 0.260991371558863 FBN2/ATP2B1/BMP7/LGR4/STIM1 5 GO:1990778 protein localization to cell periphery 8/244 333/18722 0.0708972715341537 0.261762285686774 LRP1/DAG1/ITGB1/LAMA5/MACF1/ATP2B4/SPTBN1/CDH1 8 GO:0000302 response to reactive oxygen species 6/244 222/18722 0.071075113205343 0.262124379340917 JUN/BMP7/LDHA/SOD3/MET/HYAL2 6 GO:0110053 regulation of actin filament organization 7/244 277/18722 0.071327984328698 0.262226042384279 SVIL/PPP1R9A/KANK1/TACSTD2/IQGAP2/MET/SPTBN1 7 GO:0051897 positive regulation of protein kinase B signaling 4/244 120/18722 0.0720437353264515 0.262226042384279 LRP2/MET/ITGB1/GCNT2 4 GO:0072655 establishment of protein localization to mitochondrion 4/244 120/18722 0.0720437353264515 0.262226042384279 CALM1/HUWE1/LMAN1/SREBF2 4 GO:0000038 very long-chain fatty acid metabolic process 2/244 34/18722 0.0722745319228774 0.262226042384279 HACD3/SLC27A2 2 GO:0001662 behavioral fear response 2/244 34/18722 0.0722745319228774 0.262226042384279 DPP4/GJA1 2 GO:0010614 negative regulation of cardiac muscle hypertrophy 2/244 34/18722 0.0722745319228774 0.262226042384279 JARID2/ATP2B4 2 GO:0010922 positive regulation of phosphatase activity 2/244 34/18722 0.0722745319228774 0.262226042384279 SLC39A10/CALM1 2 GO:0019320 hexose catabolic process 2/244 34/18722 0.0722745319228774 0.262226042384279 LRP5/FUT8 2 GO:0048536 spleen development 2/244 34/18722 0.0722745319228774 0.262226042384279 PBX1/JARID2 2 GO:0050931 pigment cell differentiation 2/244 34/18722 0.0722745319228774 0.262226042384279 GLI3/HPS6 2 GO:0051085 chaperone cofactor-dependent protein refolding 2/244 34/18722 0.0722745319228774 0.262226042384279 HSPA5/DNAJB14 2 GO:0070884 regulation of calcineurin-NFAT signaling cascade 2/244 34/18722 0.0722745319228774 0.262226042384279 RCAN1/ATP2B4 2 GO:0086019 cell-cell signaling involved in cardiac conduction 2/244 34/18722 0.0722745319228774 0.262226042384279 GJA5/GJA1 2 GO:0070972 protein localization to endoplasmic reticulum 3/244 74/18722 0.0722996939744847 0.262226042384279 HSPA5/MIA3/GJA1 3 GO:0120192 tight junction assembly 3/244 74/18722 0.0722996939744847 0.262226042384279 POF1B/CLDN4/GJA1 3 GO:0030833 regulation of actin filament polymerization 5/244 171/18722 0.0734385852067447 0.265770034129255 SVIL/PPP1R9A/KANK1/IQGAP2/SPTBN1 5 GO:0110148 biomineralization 5/244 171/18722 0.0734385852067447 0.265770034129255 FBN2/ATP2B1/BMP7/LGR4/STIM1 5 GO:0001838 embryonic epithelial tube formation 4/244 121/18722 0.0737824964913456 0.26584351257737 LRP2/SPINT1/BMP7/FOLR1 4 GO:0042177 negative regulation of protein catabolic process 4/244 121/18722 0.0737824964913456 0.26584351257737 USP25/SERPINE2/SVIP/CST3 4 GO:0043500 muscle adaptation 4/244 121/18722 0.0737824964913456 0.26584351257737 IL6ST/DAG1/JARID2/ATP2B4 4 GO:0045931 positive regulation of mitotic cell cycle 4/244 121/18722 0.0737824964913456 0.26584351257737 ADAMTS1/APP/PBX1/LGMN 4 GO:0008088 axo-dendritic transport 3/244 75/18722 0.0746191194758779 0.268138177204476 ARMCX3/DST/APP 3 GO:0043627 response to estrogen 3/244 75/18722 0.0746191194758779 0.268138177204476 LDHA/GLI3/KRT19 3 GO:0016485 protein processing 6/244 225/18722 0.0747457609005781 0.268138177204476 CTSL/ENPEP/DHCR24/GLI3/LGMN/SERPINE2 6 GO:0034284 response to monosaccharide 6/244 225/18722 0.0747457609005781 0.268138177204476 EFNA5/LRP5/LRP1/LDHA/CTSV/GJA1 6 GO:0051208 sequestering of calcium ion 4/244 122/18722 0.0755424586601297 0.269462509738865 MCOLN3/CALM1/P2RY6/HTT 4 GO:0071241 cellular response to inorganic substance 6/244 226/18722 0.0759929670682213 0.269462509738865 JUN/APP/HSPA5/LGMN/MTR/CDH1 6 GO:0002209 behavioral defense response 2/244 35/18722 0.0760169648593816 0.269462509738865 DPP4/GJA1 2 GO:0033280 response to vitamin D 2/244 35/18722 0.0760169648593816 0.269462509738865 ATP2B1/BMP7 2 GO:0034405 response to fluid shear stress 2/244 35/18722 0.0760169648593816 0.269462509738865 GJA1/SREBF2 2 GO:0042462 eye photoreceptor cell development 2/244 35/18722 0.0760169648593816 0.269462509738865 NAGLU/TUG1 2 GO:0045907 positive regulation of vasoconstriction 2/244 35/18722 0.0760169648593816 0.269462509738865 GJA5/GJA1 2 GO:0086005 ventricular cardiac muscle cell action potential 2/244 35/18722 0.0760169648593816 0.269462509738865 DSC2/DSG2 2 GO:0098801 regulation of renal system process 2/244 35/18722 0.0760169648593816 0.269462509738865 GJA5/GJA1 2 GO:0098810 neurotransmitter reuptake 2/244 35/18722 0.0760169648593816 0.269462509738865 SLC6A4/ITGB1 2 GO:0106056 regulation of calcineurin-mediated signaling 2/244 35/18722 0.0760169648593816 0.269462509738865 RCAN1/ATP2B4 2 GO:0000910 cytokinesis 5/244 173/18722 0.0763293432418428 0.269987321735948 SVIL/CALM1/SON/SPTBN1/MYH10 5 GO:0006694 steroid biosynthetic process 5/244 173/18722 0.0763293432418428 0.269987321735948 PBX1/SLC27A2/DHCR24/ASAH1/SF1 5 GO:1903532 positive regulation of secretion by cell 7/244 282/18722 0.0767932932683452 0.271090747465998 LRP1/ISL1/SLC6A4/KCNN4/WLS/GJA1/MYH10 7 GO:0008652 cellular amino acid biosynthetic process 3/244 76/18722 0.0769712925702302 0.271090747465998 ATP2B4/MTR/SLC1A3 3 GO:0021536 diencephalon development 3/244 76/18722 0.0769712925702302 0.271090747465998 NRP2/ISL1/CDH1 3 GO:0140115 export across plasma membrane 3/244 76/18722 0.0769712925702302 0.271090747465998 ATP2B1/CALM1/GJA1 3 GO:0010811 positive regulation of cell-substrate adhesion 4/244 123/18722 0.0773235079332403 0.272039664955704 CCDC80/UTRN/DAG1/P4HB 4 GO:0072659 protein localization to plasma membrane 7/244 284/18722 0.0790464533279136 0.277552524554021 LRP1/ITGB1/LAMA5/MACF1/ATP2B4/SPTBN1/CDH1 7 GO:0048771 tissue remodeling 5/244 175/18722 0.0792810027726246 0.277552524554021 LRP5/GJA1/LGR4/FOXC1/CST3 5 GO:0000380 alternative mRNA splicing, via spliceosome 3/244 77/18722 0.079355814343553 0.277552524554021 SRSF2/DDX5/RBM25 3 GO:0031016 pancreas development 3/244 77/18722 0.079355814343553 0.277552524554021 ISL1/MET/WLS 3 GO:0003203 endocardial cushion morphogenesis 2/244 36/18722 0.079819578729017 0.277552524554021 ISL1/BMP7 2 GO:0003230 cardiac atrium development 2/244 36/18722 0.079819578729017 0.277552524554021 ISL1/GJA5 2 GO:0009225 nucleotide-sugar metabolic process 2/244 36/18722 0.079819578729017 0.277552524554021 EXTL2/FUT8 2 GO:0010762 regulation of fibroblast migration 2/244 36/18722 0.079819578729017 0.277552524554021 ITGB1/HYAL2 2 GO:0014741 negative regulation of muscle hypertrophy 2/244 36/18722 0.079819578729017 0.277552524554021 JARID2/ATP2B4 2 GO:0051385 response to mineralocorticoid 2/244 36/18722 0.079819578729017 0.277552524554021 ATP2B1/CALM1 2 GO:1903749 positive regulation of establishment of protein localization to mitochondrion 2/244 36/18722 0.079819578729017 0.277552524554021 HUWE1/SREBF2 2 GO:0043534 blood vessel endothelial cell migration 5/244 176/18722 0.0807795609987386 0.280586936902099 EPHB4/ITGB1/MIA3/ATP2B4/AMOT 5 GO:0018210 peptidyl-threonine modification 4/244 125/18722 0.0809483920216647 0.280586936902099 GALNT11/BMP7/APP/CALM1 4 GO:0070585 protein localization to mitochondrion 4/244 125/18722 0.0809483920216647 0.280586936902099 CALM1/HUWE1/LMAN1/SREBF2 4 GO:0008306 associative learning 3/244 78/18722 0.0817722797989209 0.282548592449268 APP/ITGB1/LGMN 3 GO:0030500 regulation of bone mineralization 3/244 78/18722 0.0817722797989209 0.282548592449268 FBN2/ATP2B1/BMP7 3 GO:0032024 positive regulation of insulin secretion 3/244 78/18722 0.0817722797989209 0.282548592449268 LRP1/ISL1/GJA1 3 GO:0071453 cellular response to oxygen levels 5/244 177/18722 0.0822932085722148 0.284049877487708 TBL2/MALAT1/BMP7/P4HB/DNMT3A 5 GO:1903311 regulation of mRNA metabolic process 7/244 288/18722 0.0836674497087636 0.286877465090341 TNRC6B/SON/SRSF2/PUM1/SF1/DDX5/RBM25 7 GO:0006862 nucleotide transport 2/244 37/18722 0.0836801844806353 0.286877465090341 GJA1/SLC19A1 2 GO:0031112 positive regulation of microtubule polymerization or depolymerization 2/244 37/18722 0.0836801844806353 0.286877465090341 MET/AKAP9 2 GO:0043403 skeletal muscle tissue regeneration 2/244 37/18722 0.0836801844806353 0.286877465090341 DAG1/HOPX 2 GO:0060306 regulation of membrane repolarization 2/244 37/18722 0.0836801844806353 0.286877465090341 GJA5/AKAP9 2 GO:1905332 positive regulation of morphogenesis of an epithelium 2/244 37/18722 0.0836801844806353 0.286877465090341 GJA1/LGR4 2 GO:0010594 regulation of endothelial cell migration 6/244 232/18722 0.0837235207004373 0.286877465090341 NR2F2/NRP2/MET/ATP2B4/LGMN/PLPP3 6 GO:0032272 negative regulation of protein polymerization 3/244 79/18722 0.0842202782197906 0.287679661361987 SVIL/KANK1/SPTBN1 3 GO:0051279 regulation of release of sequestered calcium ion into cytosol 3/244 79/18722 0.0842202782197906 0.287679661361987 CALM1/P2RY6/HTT 3 GO:0060420 regulation of heart growth 3/244 79/18722 0.0842202782197906 0.287679661361987 JARID2/GJA1/TGFBR3 3 GO:0051224 negative regulation of protein transport 4/244 127/18722 0.0846561581222113 0.288868261256061 ERP29/LMAN1/SVIP/RAB11FIP1 4 GO:0010639 negative regulation of organelle organization 8/244 347/18722 0.0851524481309558 0.290260315931868 SVIL/PPP1R9A/KANK1/TACSTD2/BMP7/MET/HUWE1/SPTBN1 8 GO:0035303 regulation of dephosphorylation 4/244 128/18722 0.0865407957187305 0.294312197435193 SLC39A10/CALM1/RCAN1/HTT 4 GO:0007422 peripheral nervous system development 3/244 80/18722 0.0866993935232097 0.294312197435193 ITGB4/ISL1/DAG1 3 GO:0021766 hippocampus development 3/244 80/18722 0.0866993935232097 0.294312197435193 ATP2B4/GLI3/TSKU 3 GO:0120193 tight junction organization 3/244 80/18722 0.0866993935232097 0.294312197435193 POF1B/CLDN4/GJA1 3 GO:0048660 regulation of smooth muscle cell proliferation 5/244 180/18722 0.0869241765796444 0.294770737090518 JUN/ADAMTS1/P2RY6/GJA1/SF1 5 GO:0097242 amyloid-beta clearance 2/244 38/18722 0.0875966394793756 0.296134318239947 LRP2/LRP1 2 GO:0099622 cardiac muscle cell membrane repolarization 2/244 38/18722 0.0875966394793756 0.296134318239947 GJA5/AKAP9 2 GO:1901031 regulation of response to reactive oxygen species 2/244 38/18722 0.0875966394793756 0.296134318239947 BMP7/MET 2 GO:0030072 peptide hormone secretion 6/244 236/18722 0.0891112755660233 0.299123924822357 EFNA5/LRP5/LRP1/ISL1/DPP4/GJA1 6 GO:0000422 autophagy of mitochondrion 3/244 81/18722 0.0892092046031376 0.299123924822357 HUWE1/HTT/SREBF2 3 GO:0001523 retinoid metabolic process 3/244 81/18722 0.0892092046031376 0.299123924822357 LRP2/LRP1/RDH14 3 GO:0001942 hair follicle development 3/244 81/18722 0.0892092046031376 0.299123924822357 LGR5/LAMA5/LGR4 3 GO:0006096 glycolytic process 3/244 81/18722 0.0892092046031376 0.299123924822357 APP/LDHA/GAPDH 3 GO:0051817 modulation of process of other organism involved in symbiotic interaction 3/244 81/18722 0.0892092046031376 0.299123924822357 JUN/DAG1/HYAL2 3 GO:0061726 mitochondrion disassembly 3/244 81/18722 0.0892092046031376 0.299123924822357 HUWE1/HTT/SREBF2 3 GO:0071260 cellular response to mechanical stimulus 3/244 81/18722 0.0892092046031376 0.299123924822357 DAG1/TMEM150C/GJA1 3 GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 4/244 130/18722 0.0903708957161221 0.302401999310771 PGAP1/MIA3/TMED3/LMAN1 4 GO:0030534 adult behavior 4/244 130/18722 0.0903708957161221 0.302401999310771 NLGN4X/APP/ATP6V1B1/PUM1 4 GO:0033673 negative regulation of kinase activity 6/244 237/18722 0.0904872476919459 0.302483312223534 LRP5/NR2F2/LATS2/BMP7/GNAQ/HYAL2 6 GO:0051604 protein maturation 7/244 294/18722 0.0908845094377022 0.303502538630375 CTSL/SERPINH1/ENPEP/DHCR24/GLI3/LGMN/SERPINE2 7 GO:0010463 mesenchymal cell proliferation 2/244 39/18722 0.0915668466768869 0.3045431762958 LRP5/BMP7 2 GO:0021587 cerebellum morphogenesis 2/244 39/18722 0.0915668466768869 0.3045431762958 HSPA5/SERPINE2 2 GO:0031507 heterochromatin assembly 2/244 39/18722 0.0915668466768869 0.3045431762958 MPHOSPH8/DNMT3A 2 GO:0051084 'de novo' posttranslational protein folding 2/244 39/18722 0.0915668466768869 0.3045431762958 HSPA5/DNAJB14 2 GO:0006757 ATP generation from ADP 3/244 82/18722 0.0917492856640931 0.304841408182214 APP/LDHA/GAPDH 3 GO:0046879 hormone secretion 7/244 295/18722 0.0921205110305499 0.305765655804431 EFNA5/LRP5/LRP1/ISL1/DPP4/GJA1/RAB11FIP1 7 GO:0006661 phosphatidylinositol biosynthetic process 4/244 131/18722 0.092316073898033 0.305796994787234 CDS1/PGAP1/SACM1L/PIP5K1B 4 GO:1904950 negative regulation of establishment of protein localization 4/244 131/18722 0.092316073898033 0.305796994787234 ERP29/LMAN1/SVIP/RAB11FIP1 4 GO:0001558 regulation of cell growth 9/244 414/18722 0.0932537476521615 0.308342211603787 LRP1/SEMA6A/SEMA6D/DCBLD2/DPYSL2/GJA1/MACF1/SERPINE2/HYAL2 9 GO:0048659 smooth muscle cell proliferation 5/244 184/18722 0.0933067723486594 0.308342211603787 JUN/ADAMTS1/P2RY6/GJA1/SF1 5 GO:0051258 protein polymerization 7/244 296/18722 0.0933659466055289 0.308342211603787 SVIL/PPP1R9A/KANK1/IQGAP2/MET/AKAP9/SPTBN1 7 GO:0072175 epithelial tube formation 4/244 132/18722 0.0942811424253649 0.310865509235711 LRP2/SPINT1/BMP7/FOLR1 4 GO:0050886 endocrine process 3/244 83/18722 0.094319206545345 0.310865509235711 GJA1/ENPEP/RAB11FIP1 3 GO:0010543 regulation of platelet activation 2/244 40/18722 0.0955887537951551 0.312541935294408 IL6ST/SERPINE2 2 GO:0010863 positive regulation of phospholipase C activity 2/244 40/18722 0.0955887537951551 0.312541935294408 P2RY6/GNAQ 2 GO:0014037 Schwann cell differentiation 2/244 40/18722 0.0955887537951551 0.312541935294408 ITGB4/DAG1 2 GO:0043001 Golgi to plasma membrane protein transport 2/244 40/18722 0.0955887537951551 0.312541935294408 MACF1/SPTBN1 2 GO:0045777 positive regulation of blood pressure 2/244 40/18722 0.0955887537951551 0.312541935294408 NR2F2/ADRB1 2 GO:0046365 monosaccharide catabolic process 2/244 40/18722 0.0955887537951551 0.312541935294408 LRP5/FUT8 2 GO:0055081 anion homeostasis 2/244 40/18722 0.0955887537951551 0.312541935294408 ATP6V1B1/SLC12A9 2 GO:1901998 toxin transport 2/244 40/18722 0.0955887537951551 0.312541935294408 ANTXR2/HSPA5 2 GO:0006813 potassium ion transport 6/244 241/18722 0.0961063906501991 0.313922067272917 KCNN4/GJA5/AKAP9/ITGB1/SLC12A9/SLC1A3 6 GO:0010595 positive regulation of endothelial cell migration 4/244 133/18722 0.0962659508732274 0.314130997586321 NRP2/MET/LGMN/PLPP3 4 GO:0120032 regulation of plasma membrane bounded cell projection assembly 5/244 186/18722 0.0965861008074141 0.314863023068614 PPP1R9A/KANK1/TACSTD2/DZIP1/HTT 5 GO:0022404 molting cycle process 3/244 84/18722 0.0969185330358521 0.315321088669119 LGR5/LAMA5/LGR4 3 GO:0022405 hair cycle process 3/244 84/18722 0.0969185330358521 0.315321088669119 LGR5/LAMA5/LGR4 3 GO:0002790 peptide secretion 6/244 242/18722 0.0975398273410801 0.317028558499297 EFNA5/LRP5/LRP1/ISL1/DPP4/GJA1 6 GO:0008064 regulation of actin polymerization or depolymerization 5/244 187/18722 0.0982475410546543 0.319013260776279 SVIL/PPP1R9A/KANK1/IQGAP2/SPTBN1 5 GO:0030433 ubiquitin-dependent ERAD pathway 3/244 85/18722 0.0995468271801599 0.322009752598763 HSPA5/SVIP/DNAJB14 3 GO:0045069 regulation of viral genome replication 3/244 85/18722 0.0995468271801599 0.322009752598763 MPHOSPH8/HACD3/DDX5 3 GO:0098773 skin epidermis development 3/244 85/18722 0.0995468271801599 0.322009752598763 LGR5/LAMA5/LGR4 3 GO:0051693 actin filament capping 2/244 41/18722 0.0996603525237196 0.322009752598763 SVIL/SPTBN1 2 GO:1901385 regulation of voltage-gated calcium channel activity 2/244 41/18722 0.0996603525237196 0.322009752598763 CALM1/AHNAK 2 GO:0030832 regulation of actin filament length 5/244 188/18722 0.0999234051819739 0.322226015140301 SVIL/PPP1R9A/KANK1/IQGAP2/SPTBN1 5 GO:0060491 regulation of cell projection assembly 5/244 188/18722 0.0999234051819739 0.322226015140301 PPP1R9A/KANK1/TACSTD2/DZIP1/HTT 5 GO:0070997 neuron death 8/244 361/18722 0.100974914832736 0.325297617784678 JUN/LRP1/ISL1/APP/GAPDH/HSPA5/DHCR24/LGMN 8 GO:0072594 establishment of protein localization to organelle 9/244 422/18722 0.101809816717997 0.32766607025988 CALM1/FAM53C/HSPA5/HUWE1/GLI3/CDH1/LMAN1/SREBF2/HYAL2 9 GO:0035023 regulation of Rho protein signal transduction 3/244 86/18722 0.102203647575454 0.328290504333276 KANK1/MET/ITGB1 3 GO:1903510 mucopolysaccharide metabolic process 3/244 86/18722 0.102203647575454 0.328290504333276 ITIH5/GNS/HYAL2 3 GO:1900180 regulation of protein localization to nucleus 4/244 136/18722 0.102337264457345 0.328398682623863 LATS2/GLI3/CDH1/HYAL2 4 GO:0030041 actin filament polymerization 5/244 190/18722 0.103318113269893 0.329169904460446 SVIL/PPP1R9A/KANK1/IQGAP2/SPTBN1 5 GO:0099111 microtubule-based transport 5/244 190/18722 0.103318113269893 0.329169904460446 ARMCX3/DST/APP/IFT27/HTT 5 GO:0014912 negative regulation of smooth muscle cell migration 2/244 42/18722 0.103779677730074 0.329169904460446 LRP1/SEMA6D 2 GO:0021575 hindbrain morphogenesis 2/244 42/18722 0.103779677730074 0.329169904460446 HSPA5/SERPINE2 2 GO:0021795 cerebral cortex cell migration 2/244 42/18722 0.103779677730074 0.329169904460446 LAMB1/GLI3 2 GO:0035019 somatic stem cell population maintenance 2/244 42/18722 0.103779677730074 0.329169904460446 LRP5/BMP7 2 GO:0045214 sarcomere organization 2/244 42/18722 0.103779677730074 0.329169904460446 ITGB1/KRT19 2 GO:0045773 positive regulation of axon extension 2/244 42/18722 0.103779677730074 0.329169904460446 LRP1/MACF1 2 GO:0046688 response to copper ion 2/244 42/18722 0.103779677730074 0.329169904460446 APP/SOD3 2 GO:0072595 maintenance of protein localization in organelle 2/244 42/18722 0.103779677730074 0.329169904460446 HSPA5/GJA1 2 GO:0090317 negative regulation of intracellular protein transport 2/244 42/18722 0.103779677730074 0.329169904460446 LMAN1/SVIP 2 GO:1900274 regulation of phospholipase C activity 2/244 42/18722 0.103779677730074 0.329169904460446 P2RY6/GNAQ 2 GO:0007266 Rho protein signal transduction 4/244 137/18722 0.104399466226422 0.330179640057769 KANK1/MET/ITGB1/HACD3 4 GO:0055123 digestive system development 4/244 137/18722 0.104399466226422 0.330179640057769 IL6ST/WLS/LGR4/GLI3 4 GO:0090090 negative regulation of canonical Wnt signaling pathway 4/244 137/18722 0.104399466226422 0.330179640057769 ISL1/LATS2/TLE4/GLI3 4 GO:0016101 diterpenoid metabolic process 3/244 87/18722 0.104888549659964 0.330454241785852 LRP2/LRP1/RDH14 3 GO:0019915 lipid storage 3/244 87/18722 0.104888549659964 0.330454241785852 CDS1/ITGAV/SREBF2 3 GO:0044070 regulation of anion transport 3/244 87/18722 0.104888549659964 0.330454241785852 TCAF1/ITGB1/GABRE 3 GO:1900182 positive regulation of protein localization to nucleus 3/244 87/18722 0.104888549659964 0.330454241785852 GLI3/CDH1/HYAL2 3 GO:0050821 protein stabilization 5/244 191/18722 0.105036806675055 0.330604355109418 GAPDH/AAK1/PLPP3/TBL1X/GNAQ 5 GO:0050808 synapse organization 9/244 426/18722 0.106251682819855 0.333684510593111 NLGN4X/NRP2/PPP1R9A/APP/DAG1/LGMN/CDH1/PPFIBP1/MYH10 9 GO:0009914 hormone transport 7/244 306/18722 0.106335030496227 0.333684510593111 EFNA5/LRP5/LRP1/ISL1/DPP4/GJA1/RAB11FIP1 7 GO:0007224 smoothened signaling pathway 4/244 138/18722 0.106480609954576 0.333684510593111 DZIP1/IFT27/GLI3/SERPINE2 4 GO:0055076 transition metal ion homeostasis 4/244 138/18722 0.106480609954576 0.333684510593111 SLC39A10/APP/SLC46A1/HYAL2 4 GO:0031331 positive regulation of cellular catabolic process 9/244 427/18722 0.10737912032261 0.333684510593111 LRP2/LRP1/KCNQ1OT1/APP/TNRC6B/HTT/TMTC3/PUM1/SVIP 9 GO:0001843 neural tube closure 3/244 88/18722 0.107601085992922 0.333684510593111 LRP2/SPINT1/FOLR1 3 GO:0006284 base-excision repair 2/244 43/18722 0.107944806683042 0.333684510593111 HUWE1/APEX2 2 GO:0006458 'de novo' protein folding 2/244 43/18722 0.107944806683042 0.333684510593111 HSPA5/DNAJB14 2 GO:0009268 response to pH 2/244 43/18722 0.107944806683042 0.333684510593111 GJA1/LGMN 2 GO:0010171 body morphogenesis 2/244 43/18722 0.107944806683042 0.333684510593111 ANKRD11/DAG1 2 GO:0014002 astrocyte development 2/244 43/18722 0.107944806683042 0.333684510593111 LRP1/APP 2 GO:0021983 pituitary gland development 2/244 43/18722 0.107944806683042 0.333684510593111 ISL1/CDH1 2 GO:0030517 negative regulation of axon extension 2/244 43/18722 0.107944806683042 0.333684510593111 SEMA6A/SEMA6D 2 GO:0033173 calcineurin-NFAT signaling cascade 2/244 43/18722 0.107944806683042 0.333684510593111 RCAN1/ATP2B4 2 GO:0045776 negative regulation of blood pressure 2/244 43/18722 0.107944806683042 0.333684510593111 ADRB1/GJA5 2 GO:0060443 mammary gland morphogenesis 2/244 43/18722 0.107944806683042 0.333684510593111 LRP5/GLI3 2 GO:0098815 modulation of excitatory postsynaptic potential 2/244 43/18722 0.107944806683042 0.333684510593111 NLGN4X/APP 2 GO:1901381 positive regulation of potassium ion transmembrane transport 2/244 43/18722 0.107944806683042 0.333684510593111 KCNN4/AKAP9 2 GO:1903793 positive regulation of anion transport 2/244 43/18722 0.107944806683042 0.333684510593111 TCAF1/ITGB1 2 GO:0045598 regulation of fat cell differentiation 4/244 139/18722 0.108580527476538 0.335334223014948 LRP5/BMP7/CDS1/ANKRD26 4 GO:1901654 response to ketone 5/244 194/18722 0.110277302921336 0.340131229123117 ATP2B1/CALM1/CLDN4/P2RY6/TGFBR3 5 GO:0060606 tube closure 3/244 89/18722 0.110340806526246 0.340131229123117 LRP2/SPINT1/FOLR1 3 GO:0015748 organophosphate ester transport 4/244 140/18722 0.110699047964762 0.340915718474422 KCNN4/GJA1/SLC19A1/PLEKHA8 4 GO:0051047 positive regulation of secretion 7/244 310/18722 0.111781600099199 0.341871594005052 LRP1/ISL1/SLC6A4/KCNN4/WLS/GJA1/MYH10 7 GO:0006775 fat-soluble vitamin metabolic process 2/244 44/18722 0.112153858288937 0.341871594005052 LRP2/LGMN 2 GO:0007528 neuromuscular junction development 2/244 44/18722 0.112153858288937 0.341871594005052 APP/PPFIBP1 2 GO:0008542 visual learning 2/244 44/18722 0.112153858288937 0.341871594005052 APP/ITGB1 2 GO:0021517 ventral spinal cord development 2/244 44/18722 0.112153858288937 0.341871594005052 ISL1/GLI3 2 GO:0021762 substantia nigra development 2/244 44/18722 0.112153858288937 0.341871594005052 CALM1/HSPA5 2 GO:0048066 developmental pigmentation 2/244 44/18722 0.112153858288937 0.341871594005052 GLI3/HPS6 2 GO:0050999 regulation of nitric-oxide synthase activity 2/244 44/18722 0.112153858288937 0.341871594005052 CALM1/ATP2B4 2 GO:0060711 labyrinthine layer development 2/244 44/18722 0.112153858288937 0.341871594005052 SPINT1/BMP7 2 GO:0089718 amino acid import across plasma membrane 2/244 44/18722 0.112153858288937 0.341871594005052 ITGB1/SLC1A3 2 GO:0097178 ruffle assembly 2/244 44/18722 0.112153858288937 0.341871594005052 KANK1/TACSTD2 2 GO:0030901 midbrain development 3/244 90/18722 0.113107258868155 0.343503190980366 CALM1/HSPA5/WLS 3 GO:0046031 ADP metabolic process 3/244 90/18722 0.113107258868155 0.343503190980366 APP/LDHA/GAPDH 3 GO:0046849 bone remodeling 3/244 90/18722 0.113107258868155 0.343503190980366 LRP5/GJA1/LGR4 3 GO:0097581 lamellipodium organization 3/244 90/18722 0.113107258868155 0.343503190980366 KANK1/ITGB1/VCL 3 GO:0043393 regulation of protein binding 5/244 196/18722 0.113840494071507 0.345410769638941 LRP1/APP/DZIP1/TGFBR3/HOPX 5 GO:0009743 response to carbohydrate 6/244 253/18722 0.114050704064163 0.345729348297823 EFNA5/LRP5/LRP1/LDHA/CTSV/GJA1 6 GO:0046467 membrane lipid biosynthetic process 4/244 142/18722 0.1149912017126 0.348259068043875 PGAP1/HACD3/ASAH1/PLPP3 4 GO:0042594 response to starvation 5/244 197/18722 0.115642692875233 0.348366853215094 JUN/TBL2/CTSV/HSPA5/SREBF2 5 GO:0071248 cellular response to metal ion 5/244 197/18722 0.115642692875233 0.348366853215094 JUN/APP/HSPA5/LGMN/CDH1 5 GO:0051492 regulation of stress fiber assembly 3/244 91/18722 0.115899988538885 0.348366853215094 PPP1R9A/TACSTD2/MET 3 GO:0060191 regulation of lipase activity 3/244 91/18722 0.115899988538885 0.348366853215094 LRP1/P2RY6/GNAQ 3 GO:0045787 positive regulation of cell cycle 7/244 313/18722 0.115962087265019 0.348366853215094 SVIL/LRP5/ADAMTS1/SLC6A4/APP/PBX1/LGMN 7 GO:0003197 endocardial cushion development 2/244 45/18722 0.116404992340284 0.348366853215094 ISL1/BMP7 2 GO:0022602 ovulation cycle process 2/244 45/18722 0.116404992340284 0.348366853215094 ADAMTS1/HSPA5 2 GO:0030835 negative regulation of actin filament depolymerization 2/244 45/18722 0.116404992340284 0.348366853215094 SVIL/SPTBN1 2 GO:0030850 prostate gland development 2/244 45/18722 0.116404992340284 0.348366853215094 BMP7/GLI3 2 GO:0031670 cellular response to nutrient 2/244 45/18722 0.116404992340284 0.348366853215094 ATP2B1/FOLR1 2 GO:0035307 positive regulation of protein dephosphorylation 2/244 45/18722 0.116404992340284 0.348366853215094 SLC39A10/CALM1 2 GO:0048538 thymus development 2/244 45/18722 0.116404992340284 0.348366853215094 PBX1/JARID2 2 GO:0085029 extracellular matrix assembly 2/244 45/18722 0.116404992340284 0.348366853215094 LAMB1/DAG1 2 GO:0006865 amino acid transport 4/244 143/18722 0.117164480744613 0.350250317895714 ITGB1/SLC38A9/GJA1/SLC1A3 4 GO:0018108 peptidyl-tyrosine phosphorylation 8/244 375/18722 0.11833959326729 0.350250317895714 EFNA5/EPHB4/IL6ST/ISL1/APP/MET/EFEMP1/HYAL2 8 GO:0001708 cell fate specification 3/244 92/18722 0.118718539218688 0.350250317895714 ISL1/ITGB1/GLI3 3 GO:0050673 epithelial cell proliferation 9/244 437/18722 0.119023749381433 0.350250317895714 LGR5/LAMC1/NR2F2/NRP2/LAMB1/ISL1/GJA1/LGR4/TGFBR3 9 GO:0031644 regulation of nervous system process 4/244 144/18722 0.119355654449195 0.350250317895714 NLGN4X/APP/AKAP9/DAG1 4 GO:0001974 blood vessel remodeling 2/244 46/18722 0.12069640877694 0.350250317895714 FOXC1/CST3 2 GO:0006984 ER-nucleus signaling pathway 2/244 46/18722 0.12069640877694 0.350250317895714 HSPA5/SREBF2 2 GO:0031057 negative regulation of histone modification 2/244 46/18722 0.12069640877694 0.350250317895714 JARID2/MLLT6 2 GO:0046839 phospholipid dephosphorylation 2/244 46/18722 0.12069640877694 0.350250317895714 SACM1L/PLPP3 2 GO:0060976 coronary vasculature development 2/244 46/18722 0.12069640877694 0.350250317895714 LRP2/TGFBR3 2 GO:0070828 heterochromatin organization 2/244 46/18722 0.12069640877694 0.350250317895714 MPHOSPH8/DNMT3A 2 GO:0032755 positive regulation of interleukin-6 production 3/244 93/18722 0.121562452988284 0.350250317895714 ISL1/APP/HYAL2 3 GO:0106027 neuron projection organization 3/244 93/18722 0.121562452988284 0.350250317895714 PPP1R9A/APP/LGMN 3 GO:1901992 positive regulation of mitotic cell cycle phase transition 3/244 93/18722 0.121562452988284 0.350250317895714 ADAMTS1/APP/PBX1 3 GO:0018212 peptidyl-tyrosine modification 8/244 378/18722 0.12225704339285 0.350250317895714 EFNA5/EPHB4/IL6ST/ISL1/APP/MET/EFEMP1/HYAL2 8 GO:0001820 serotonin secretion 1/244 10/18722 0.122972058642303 0.350250317895714 SLC6A4 1 GO:0002002 regulation of angiotensin levels in blood 1/244 10/18722 0.122972058642303 0.350250317895714 ENPEP 1 GO:0002003 angiotensin maturation 1/244 10/18722 0.122972058642303 0.350250317895714 ENPEP 1 GO:0002934 desmosome organization 1/244 10/18722 0.122972058642303 0.350250317895714 DSG2 1 GO:0003056 regulation of vascular associated smooth muscle contraction 1/244 10/18722 0.122972058642303 0.350250317895714 ATP2B1 1 GO:0003163 sinoatrial node development 1/244 10/18722 0.122972058642303 0.350250317895714 ISL1 1 GO:0010172 embryonic body morphogenesis 1/244 10/18722 0.122972058642303 0.350250317895714 DAG1 1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 1/244 10/18722 0.122972058642303 0.350250317895714 P4HB 1 GO:0019532 oxalate transport 1/244 10/18722 0.122972058642303 0.350250317895714 SLC26A2 1 GO:0021562 vestibulocochlear nerve development 1/244 10/18722 0.122972058642303 0.350250317895714 NRP2 1 GO:0030214 hyaluronan catabolic process 1/244 10/18722 0.122972058642303 0.350250317895714 HYAL2 1 GO:0031118 rRNA pseudouridine synthesis 1/244 10/18722 0.122972058642303 0.350250317895714 NAF1 1 GO:0035376 sterol import 1/244 10/18722 0.122972058642303 0.350250317895714 LRP1 1 GO:0048340 paraxial mesoderm morphogenesis 1/244 10/18722 0.122972058642303 0.350250317895714 FOXC1 1 GO:0048672 positive regulation of collateral sprouting 1/244 10/18722 0.122972058642303 0.350250317895714 LRP1 1 GO:0048755 branching morphogenesis of a nerve 1/244 10/18722 0.122972058642303 0.350250317895714 RERE 1 GO:0050861 positive regulation of B cell receptor signaling pathway 1/244 10/18722 0.122972058642303 0.350250317895714 SLC39A10 1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 1/244 10/18722 0.122972058642303 0.350250317895714 CALM1 1 GO:0060068 vagina development 1/244 10/18722 0.122972058642303 0.350250317895714 LRP2 1 GO:0060272 embryonic skeletal joint morphogenesis 1/244 10/18722 0.122972058642303 0.350250317895714 BMP7 1 GO:0060513 prostatic bud formation 1/244 10/18722 0.122972058642303 0.350250317895714 BMP7 1 GO:0061299 retina vasculature morphogenesis in camera-type eye 1/244 10/18722 0.122972058642303 0.350250317895714 LRP5 1 GO:0070508 cholesterol import 1/244 10/18722 0.122972058642303 0.350250317895714 LRP1 1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum 1/244 10/18722 0.122972058642303 0.350250317895714 SVIP 1 GO:0072124 regulation of glomerular mesangial cell proliferation 1/244 10/18722 0.122972058642303 0.350250317895714 BMP7 1 GO:0072203 cell proliferation involved in metanephros development 1/244 10/18722 0.122972058642303 0.350250317895714 BMP7 1 GO:0090647 modulation of age-related behavioral decline 1/244 10/18722 0.122972058642303 0.350250317895714 APP 1 GO:0097105 presynaptic membrane assembly 1/244 10/18722 0.122972058642303 0.350250317895714 NLGN4X 1 GO:0098885 modification of postsynaptic actin cytoskeleton 1/244 10/18722 0.122972058642303 0.350250317895714 MYH10 1 GO:0098917 retrograde trans-synaptic signaling 1/244 10/18722 0.122972058642303 0.350250317895714 DAG1 1 GO:1900246 positive regulation of RIG-I signaling pathway 1/244 10/18722 0.122972058642303 0.350250317895714 PUM1 1 GO:1901203 positive regulation of extracellular matrix assembly 1/244 10/18722 0.122972058642303 0.350250317895714 DAG1 1 GO:1902023 L-arginine transport 1/244 10/18722 0.122972058642303 0.350250317895714 SLC38A9 1 GO:1903826 arginine transmembrane transport 1/244 10/18722 0.122972058642303 0.350250317895714 SLC38A9 1 GO:1903867 extraembryonic membrane development 1/244 10/18722 0.122972058642303 0.350250317895714 BMP7 1 GO:1990535 neuron projection maintenance 1/244 10/18722 0.122972058642303 0.350250317895714 APP 1 GO:2000121 regulation of removal of superoxide radicals 1/244 10/18722 0.122972058642303 0.350250317895714 BMP7 1 GO:2000169 regulation of peptidyl-cysteine S-nitrosylation 1/244 10/18722 0.122972058642303 0.350250317895714 ATP2B4 1 GO:2000288 positive regulation of myoblast proliferation 1/244 10/18722 0.122972058642303 0.350250317895714 MALAT1 1 GO:2001225 regulation of chloride transport 1/244 10/18722 0.122972058642303 0.350250317895714 GABRE 1 GO:0002042 cell migration involved in sprouting angiogenesis 3/244 94/18722 0.124431270561952 0.350250317895714 EPHB4/ITGB1/MIA3 3 GO:0019722 calcium-mediated signaling 5/244 202/18722 0.124856141280189 0.350250317895714 PPP1R9A/CALM1/RCAN1/ATP2B4/HTT 5 GO:0001754 eye photoreceptor cell differentiation 2/244 47/18722 0.125026346959387 0.350250317895714 NAGLU/TUG1 2 GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 2/244 47/18722 0.125026346959387 0.350250317895714 ADRB1/ENPEP 2 GO:0010712 regulation of collagen metabolic process 2/244 47/18722 0.125026346959387 0.350250317895714 ITGB1/CST3 2 GO:0010761 fibroblast migration 2/244 47/18722 0.125026346959387 0.350250317895714 ITGB1/HYAL2 2 GO:0032369 negative regulation of lipid transport 2/244 47/18722 0.125026346959387 0.350250317895714 ITGAV/SREBF2 2 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 2/244 47/18722 0.125026346959387 0.350250317895714 JUN/HSPA5 2 GO:0045747 positive regulation of Notch signaling pathway 2/244 47/18722 0.125026346959387 0.350250317895714 IL6ST/AAK1 2 GO:0048512 circadian behavior 2/244 47/18722 0.125026346959387 0.350250317895714 ADRB1/NAGLU 2 GO:0009416 response to light stimulus 7/244 320/18722 0.126030081630658 0.350250317895714 SCARA3/APP/CDS1/ITGB1/GNAQ/HYAL2/SLC1A3 7 GO:0009895 negative regulation of catabolic process 7/244 320/18722 0.126030081630658 0.350250317895714 MET/ATP2B4/NAF1/USP25/SERPINE2/SVIP/CST3 7 GO:0001889 liver development 4/244 147/18722 0.126034703631251 0.350250317895714 MET/JARID2/GLI3/TGFBR3 4 GO:0060041 retina development in camera-type eye 4/244 147/18722 0.126034703631251 0.350250317895714 LRP5/ATP2B1/NAGLU/ATP2B4 4 GO:1903531 negative regulation of secretion by cell 4/244 147/18722 0.126034703631251 0.350250317895714 PPP1R9A/ERP29/GJA1/RAB11FIP1 4 GO:0006643 membrane lipid metabolic process 5/244 203/18722 0.126738671124601 0.350250317895714 PGAP1/HACD3/ITGB8/ASAH1/PLPP3 5 GO:1901379 regulation of potassium ion transmembrane transport 3/244 95/18722 0.127324531513406 0.350250317895714 KCNN4/AKAP9/ITGB1 3 GO:0035148 tube formation 4/244 148/18722 0.128295605481379 0.350250317895714 LRP2/SPINT1/BMP7/FOLR1 4 GO:0050905 neuromuscular process 4/244 148/18722 0.128295605481379 0.350250317895714 APP/TMEM150C/IGDCC3/SLC1A3 4 GO:0051384 response to glucocorticoid 4/244 148/18722 0.128295605481379 0.350250317895714 ISL1/ATP2B1/CALM1/CTSV 4 GO:1903900 regulation of viral life cycle 4/244 148/18722 0.128295605481379 0.350250317895714 MPHOSPH8/HACD3/P4HB/DDX5 4 GO:0009636 response to toxic substance 6/244 262/18722 0.128544407626698 0.350250317895714 PPP1R9A/SLC6A4/BMP7/SOD3/CDH1/DNMT3A 6 GO:0031330 negative regulation of cellular catabolic process 6/244 262/18722 0.128544407626698 0.350250317895714 MET/ATP2B4/NAF1/USP25/SVIP/CST3 6 GO:0002686 negative regulation of leukocyte migration 2/244 48/18722 0.129393084954034 0.350250317895714 MIA3/DPP4 2 GO:0035036 sperm-egg recognition 2/244 48/18722 0.129393084954034 0.350250317895714 FOLR1/SPESP1 2 GO:0042149 cellular response to glucose starvation 2/244 48/18722 0.129393084954034 0.350250317895714 TBL2/HSPA5 2 GO:0097720 calcineurin-mediated signaling 2/244 48/18722 0.129393084954034 0.350250317895714 RCAN1/ATP2B4 2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 2/244 48/18722 0.129393084954034 0.350250317895714 PDIA3/HYAL2 2 GO:0042632 cholesterol homeostasis 3/244 96/18722 0.130241774494648 0.350250317895714 LRP5/SREBF2/TSKU 3 GO:0043648 dicarboxylic acid metabolic process 3/244 96/18722 0.130241774494648 0.350250317895714 FOLR1/SLC46A1/SLC19A1 3 GO:0051592 response to calcium ion 4/244 149/18722 0.130573466424928 0.350250317895714 CALM1/HSPA5/LGMN/STIM1 4 GO:0015833 peptide transport 6/244 264/18722 0.131881433070065 0.350250317895714 EFNA5/LRP5/LRP1/ISL1/DPP4/GJA1 6 GO:0008544 epidermis development 7/244 324/18722 0.131976794341072 0.350250317895714 LGR5/MCOLN3/PALLD/LAMA5/LGR4/ASAH1/FOXC1 7 GO:0061008 hepaticobiliary system development 4/244 150/18722 0.132868093430632 0.350250317895714 MET/JARID2/GLI3/TGFBR3 4 GO:0006721 terpenoid metabolic process 3/244 97/18722 0.133182537447927 0.350250317895714 LRP2/LRP1/RDH14 3 GO:0055092 sterol homeostasis 3/244 97/18722 0.133182537447927 0.350250317895714 LRP5/SREBF2/TSKU 3 GO:0070167 regulation of biomineral tissue development 3/244 97/18722 0.133182537447927 0.350250317895714 FBN2/ATP2B1/BMP7 3 GO:0007602 phototransduction 2/244 49/18722 0.133794938830321 0.350250317895714 CDS1/GNAQ 2 GO:0007622 rhythmic behavior 2/244 49/18722 0.133794938830321 0.350250317895714 ADRB1/NAGLU 2 GO:0008038 neuron recognition 2/244 49/18722 0.133794938830321 0.350250317895714 PALLD/APP 2 GO:0009409 response to cold 2/244 49/18722 0.133794938830321 0.350250317895714 ADRB1/ATP2B1 2 GO:0014075 response to amine 2/244 49/18722 0.133794938830321 0.350250317895714 CALM1/GLDC 2 GO:0018198 peptidyl-cysteine modification 2/244 49/18722 0.133794938830321 0.350250317895714 GAPDH/ATP2B4 2 GO:0021515 cell differentiation in spinal cord 2/244 49/18722 0.133794938830321 0.350250317895714 ISL1/GLI3 2 GO:0034332 adherens junction organization 2/244 49/18722 0.133794938830321 0.350250317895714 VCL/CDH1 2 GO:0042461 photoreceptor cell development 2/244 49/18722 0.133794938830321 0.350250317895714 NAGLU/TUG1 2 GO:0052372 modulation by symbiont of entry into host 2/244 49/18722 0.133794938830321 0.350250317895714 ITGAV/P4HB 2 GO:0060986 endocrine hormone secretion 2/244 49/18722 0.133794938830321 0.350250317895714 GJA1/RAB11FIP1 2 GO:0086009 membrane repolarization 2/244 49/18722 0.133794938830321 0.350250317895714 GJA5/AKAP9 2 GO:1901799 negative regulation of proteasomal protein catabolic process 2/244 49/18722 0.133794938830321 0.350250317895714 USP25/SVIP 2 GO:1904752 regulation of vascular associated smooth muscle cell migration 2/244 49/18722 0.133794938830321 0.350250317895714 LRP1/ADAMTS1 2 GO:0001967 suckling behavior 1/244 11/18722 0.134408293020845 0.350250317895714 APP 1 GO:0003174 mitral valve development 1/244 11/18722 0.134408293020845 0.350250317895714 GJA5 1 GO:0003263 cardioblast proliferation 1/244 11/18722 0.134408293020845 0.350250317895714 ISL1 1 GO:0003264 regulation of cardioblast proliferation 1/244 11/18722 0.134408293020845 0.350250317895714 ISL1 1 GO:0006527 arginine catabolic process 1/244 11/18722 0.134408293020845 0.350250317895714 ATP2B4 1 GO:0009235 cobalamin metabolic process 1/244 11/18722 0.134408293020845 0.350250317895714 MTR 1 GO:0009313 oligosaccharide catabolic process 1/244 11/18722 0.134408293020845 0.350250317895714 MANBA 1 GO:0014854 response to inactivity 1/244 11/18722 0.134408293020845 0.350250317895714 DAG1 1 GO:0015886 heme transport 1/244 11/18722 0.134408293020845 0.350250317895714 SLC46A1 1 GO:0021561 facial nerve development 1/244 11/18722 0.134408293020845 0.350250317895714 NRP2 1 GO:0021604 cranial nerve structural organization 1/244 11/18722 0.134408293020845 0.350250317895714 NRP2 1 GO:0021610 facial nerve morphogenesis 1/244 11/18722 0.134408293020845 0.350250317895714 NRP2 1 GO:0032276 regulation of gonadotropin secretion 1/244 11/18722 0.134408293020845 0.350250317895714 GJA1 1 GO:0032610 interleukin-1 alpha production 1/244 11/18722 0.134408293020845 0.350250317895714 ISL1 1 GO:0032650 regulation of interleukin-1 alpha production 1/244 11/18722 0.134408293020845 0.350250317895714 ISL1 1 GO:0032957 inositol trisphosphate metabolic process 1/244 11/18722 0.134408293020845 0.350250317895714 P2RY6 1 GO:0033197 response to vitamin E 1/244 11/18722 0.134408293020845 0.350250317895714 SRSF2 1 GO:0033327 Leydig cell differentiation 1/244 11/18722 0.134408293020845 0.350250317895714 SF1 1 GO:0033632 regulation of cell-cell adhesion mediated by integrin 1/244 11/18722 0.134408293020845 0.350250317895714 DPP4 1 GO:0043589 skin morphogenesis 1/244 11/18722 0.134408293020845 0.350250317895714 ITGB4 1 GO:0045060 negative thymic T cell selection 1/244 11/18722 0.134408293020845 0.350250317895714 GLI3 1 GO:0045657 positive regulation of monocyte differentiation 1/244 11/18722 0.134408293020845 0.350250317895714 JUN 1 GO:0046598 positive regulation of viral entry into host cell 1/244 11/18722 0.134408293020845 0.350250317895714 P4HB 1 GO:0046929 negative regulation of neurotransmitter secretion 1/244 11/18722 0.134408293020845 0.350250317895714 PPP1R9A 1 GO:0048102 autophagic cell death 1/244 11/18722 0.134408293020845 0.350250317895714 CTSV 1 GO:0048680 positive regulation of axon regeneration 1/244 11/18722 0.134408293020845 0.350250317895714 LRP1 1 GO:0051574 positive regulation of histone H3-K9 methylation 1/244 11/18722 0.134408293020845 0.350250317895714 JARID2 1 GO:0051610 serotonin uptake 1/244 11/18722 0.134408293020845 0.350250317895714 SLC6A4 1 GO:0051657 maintenance of organelle location 1/244 11/18722 0.134408293020845 0.350250317895714 AKAP9 1 GO:0060312 regulation of blood vessel remodeling 1/244 11/18722 0.134408293020845 0.350250317895714 CST3 1 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 1/244 11/18722 0.134408293020845 0.350250317895714 CALM1 1 GO:0060379 cardiac muscle cell myoblast differentiation 1/244 11/18722 0.134408293020845 0.350250317895714 ISL1 1 GO:0060579 ventral spinal cord interneuron fate commitment 1/244 11/18722 0.134408293020845 0.350250317895714 GLI3 1 GO:0060581 cell fate commitment involved in pattern specification 1/244 11/18722 0.134408293020845 0.350250317895714 GLI3 1 GO:0061314 Notch signaling involved in heart development 1/244 11/18722 0.134408293020845 0.350250317895714 GALNT11 1 GO:0070778 L-aspartate transmembrane transport 1/244 11/18722 0.134408293020845 0.350250317895714 SLC1A3 1 GO:0071679 commissural neuron axon guidance 1/244 11/18722 0.134408293020845 0.350250317895714 DAG1 1 GO:0071888 macrophage apoptotic process 1/244 11/18722 0.134408293020845 0.350250317895714 CTSL 1 GO:0072110 glomerular mesangial cell proliferation 1/244 11/18722 0.134408293020845 0.350250317895714 BMP7 1 GO:0072173 metanephric tubule morphogenesis 1/244 11/18722 0.134408293020845 0.350250317895714 LGR4 1 GO:0075294 positive regulation by symbiont of entry into host 1/244 11/18722 0.134408293020845 0.350250317895714 P4HB 1 GO:0086016 AV node cell action potential 1/244 11/18722 0.134408293020845 0.350250317895714 GJA5 1 GO:0086027 AV node cell to bundle of His cell signaling 1/244 11/18722 0.134408293020845 0.350250317895714 GJA5 1 GO:0086070 SA node cell to atrial cardiac muscle cell communication 1/244 11/18722 0.134408293020845 0.350250317895714 GJA5 1 GO:0090309 positive regulation of DNA methylation-dependent heterochromatin assembly 1/244 11/18722 0.134408293020845 0.350250317895714 MPHOSPH8 1 GO:0090394 negative regulation of excitatory postsynaptic potential 1/244 11/18722 0.134408293020845 0.350250317895714 NLGN4X 1 GO:0097090 presynaptic membrane organization 1/244 11/18722 0.134408293020845 0.350250317895714 NLGN4X 1 GO:0097104 postsynaptic membrane assembly 1/244 11/18722 0.134408293020845 0.350250317895714 NLGN4X 1 GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 1/244 11/18722 0.134408293020845 0.350250317895714 ATP2B4 1 GO:0140042 lipid droplet formation 1/244 11/18722 0.134408293020845 0.350250317895714 CDS1 1 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction 1/244 11/18722 0.134408293020845 0.350250317895714 CALM1 1 GO:1903897 regulation of PERK-mediated unfolded protein response 1/244 11/18722 0.134408293020845 0.350250317895714 HSPA5 1 GO:1905050 positive regulation of metallopeptidase activity 1/244 11/18722 0.134408293020845 0.350250317895714 CLDN4 1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 1/244 11/18722 0.134408293020845 0.350250317895714 HSPA5 1 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 1/244 11/18722 0.134408293020845 0.350250317895714 LRP1 1 GO:2000392 regulation of lamellipodium morphogenesis 1/244 11/18722 0.134408293020845 0.350250317895714 KANK1 1 GO:2001053 regulation of mesenchymal cell apoptotic process 1/244 11/18722 0.134408293020845 0.350250317895714 BMP7 1 GO:0055067 monovalent inorganic cation homeostasis 4/244 151/18722 0.135179291672257 0.351701625047534 ATP6V1B1/SLC12A9/MLLT6/SLC1A3 4 GO:2001236 regulation of extrinsic apoptotic signaling pathway 4/244 151/18722 0.135179291672257 0.351701625047534 ITGAV/HTT/PDIA3/HYAL2 4 GO:0003333 amino acid transmembrane transport 3/244 98/18722 0.136146357810999 0.35393744601815 ITGB1/SLC38A9/SLC1A3 3 GO:0006836 neurotransmitter transport 5/244 208/18722 0.136345164911647 0.354174080553101 PPP1R9A/SLC6A4/CALM1/ITGB1/SLC1A3 5 GO:0007632 visual behavior 2/244 50/18722 0.138230261969456 0.356748935930863 APP/ITGB1 2 GO:0043268 positive regulation of potassium ion transport 2/244 50/18722 0.138230261969456 0.356748935930863 KCNN4/AKAP9 2 GO:0045058 T cell selection 2/244 50/18722 0.138230261969456 0.356748935930863 CTSL/GLI3 2 GO:0045814 negative regulation of gene expression, epigenetic 2/244 50/18722 0.138230261969456 0.356748935930863 MPHOSPH8/DNMT3A 2 GO:0050873 brown fat cell differentiation 2/244 50/18722 0.138230261969456 0.356748935930863 ADRB1/BMP7 2 GO:0071709 membrane assembly 2/244 50/18722 0.138230261969456 0.356748935930863 NLGN4X/SPTBN1 2 GO:0099054 presynapse assembly 2/244 50/18722 0.138230261969456 0.356748935930863 NLGN4X/APP 2 GO:1904738 vascular associated smooth muscle cell migration 2/244 50/18722 0.138230261969456 0.356748935930863 LRP1/ADAMTS1 2 GO:0051348 negative regulation of transferase activity 6/244 268/18722 0.138678747967697 0.356748935930863 LRP5/NR2F2/LATS2/BMP7/GNAQ/HYAL2 6 GO:0003300 cardiac muscle hypertrophy 3/244 99/18722 0.139132772715807 0.356748935930863 IL6ST/JARID2/ATP2B4 3 GO:0006165 nucleoside diphosphate phosphorylation 3/244 99/18722 0.139132772715807 0.356748935930863 APP/LDHA/GAPDH 3 GO:0110149 regulation of biomineralization 3/244 99/18722 0.139132772715807 0.356748935930863 FBN2/ATP2B1/BMP7 3 GO:0006626 protein targeting to mitochondrion 3/244 100/18722 0.142141319180763 0.356748935930863 HUWE1/LMAN1/SREBF2 3 GO:0051588 regulation of neurotransmitter transport 3/244 100/18722 0.142141319180763 0.356748935930863 PPP1R9A/CALM1/ITGB1 3 GO:0060079 excitatory postsynaptic potential 3/244 100/18722 0.142141319180763 0.356748935930863 NLGN4X/PPP1R9A/APP 3 GO:0061640 cytoskeleton-dependent cytokinesis 3/244 100/18722 0.142141319180763 0.356748935930863 SON/SPTBN1/MYH10 3 GO:0110020 regulation of actomyosin structure organization 3/244 100/18722 0.142141319180763 0.356748935930863 PPP1R9A/TACSTD2/MET 3 GO:0050770 regulation of axonogenesis 4/244 154/18722 0.142210340177167 0.356748935930863 LRP1/SEMA6A/SEMA6D/MACF1 4 GO:0009948 anterior/posterior axis specification 2/244 51/18722 0.142697444384588 0.356748935930863 PGAP1/WLS 2 GO:0010874 regulation of cholesterol efflux 2/244 51/18722 0.142697444384588 0.356748935930863 LRP1/SREBF2 2 GO:0021872 forebrain generation of neurons 2/244 51/18722 0.142697444384588 0.356748935930863 NRP2/GLI3 2 GO:0045104 intermediate filament cytoskeleton organization 2/244 51/18722 0.142697444384588 0.356748935930863 DST/MACF1 2 GO:0048013 ephrin receptor signaling pathway 2/244 51/18722 0.142697444384588 0.356748935930863 EFNA5/EPHB4 2 GO:0051339 regulation of lyase activity 2/244 51/18722 0.142697444384588 0.356748935930863 AKAP9/STIM1 2 GO:0007346 regulation of mitotic cell cycle 9/244 457/18722 0.144285899005753 0.356748935930863 LRP5/ADAMTS1/BMP7/APP/PBX1/BTG3/LGMN/FOXC1/CTDSPL 9 GO:0006606 protein import into nucleus 4/244 155/18722 0.14458584177856 0.356748935930863 FAM53C/GLI3/CDH1/HYAL2 4 GO:0006665 sphingolipid metabolic process 4/244 155/18722 0.14458584177856 0.356748935930863 HACD3/ITGB8/ASAH1/PLPP3 4 GO:0007519 skeletal muscle tissue development 4/244 155/18722 0.14458584177856 0.356748935930863 SVIL/NR2F2/RCAN1/DDX5 4 GO:0034614 cellular response to reactive oxygen species 4/244 155/18722 0.14458584177856 0.356748935930863 JUN/BMP7/SOD3/MET 4 GO:0046939 nucleotide phosphorylation 3/244 101/18722 0.145171534296764 0.356748935930863 APP/LDHA/GAPDH 3 GO:0000491 small nucleolar ribonucleoprotein complex assembly 1/244 12/18722 0.14569600487499 0.356748935930863 NAF1 1 GO:0002024 diet induced thermogenesis 1/244 12/18722 0.14569600487499 0.356748935930863 ADRB1 1 GO:0002903 negative regulation of B cell apoptotic process 1/244 12/18722 0.14569600487499 0.356748935930863 SLC39A10 1 GO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane 1/244 12/18722 0.14569600487499 0.356748935930863 HSPA5 1 GO:0007614 short-term memory 1/244 12/18722 0.14569600487499 0.356748935930863 RCAN1 1 GO:0009086 methionine biosynthetic process 1/244 12/18722 0.14569600487499 0.356748935930863 MTR 1 GO:0010587 miRNA catabolic process 1/244 12/18722 0.14569600487499 0.356748935930863 KCNQ1OT1 1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway 1/244 12/18722 0.14569600487499 0.356748935930863 LRP1 1 GO:0021559 trigeminal nerve development 1/244 12/18722 0.14569600487499 0.356748935930863 ISL1 1 GO:0021670 lateral ventricle development 1/244 12/18722 0.14569600487499 0.356748935930863 TSKU 1 GO:0021936 regulation of cerebellar granule cell precursor proliferation 1/244 12/18722 0.14569600487499 0.356748935930863 SLC6A4 1 GO:0030238 male sex determination 1/244 12/18722 0.14569600487499 0.356748935930863 SF1 1 GO:0031453 positive regulation of heterochromatin assembly 1/244 12/18722 0.14569600487499 0.356748935930863 MPHOSPH8 1 GO:0032908 regulation of transforming growth factor beta1 production 1/244 12/18722 0.14569600487499 0.356748935930863 TSKU 1 GO:0034333 adherens junction assembly 1/244 12/18722 0.14569600487499 0.356748935930863 VCL 1 GO:0038180 nerve growth factor signaling pathway 1/244 12/18722 0.14569600487499 0.356748935930863 KIDINS220 1 GO:0042117 monocyte activation 1/244 12/18722 0.14569600487499 0.356748935930863 HYAL2 1 GO:0043383 negative T cell selection 1/244 12/18722 0.14569600487499 0.356748935930863 GLI3 1 GO:0045117 azole transmembrane transport 1/244 12/18722 0.14569600487499 0.356748935930863 SLC19A3 1 GO:0046541 saliva secretion 1/244 12/18722 0.14569600487499 0.356748935930863 KCNN4 1 GO:0048934 peripheral nervous system neuron differentiation 1/244 12/18722 0.14569600487499 0.356748935930863 ISL1 1 GO:0048935 peripheral nervous system neuron development 1/244 12/18722 0.14569600487499 0.356748935930863 ISL1 1 GO:0051001 negative regulation of nitric-oxide synthase activity 1/244 12/18722 0.14569600487499 0.356748935930863 ATP2B4 1 GO:0060019 radial glial cell differentiation 1/244 12/18722 0.14569600487499 0.356748935930863 GLI3 1 GO:0060221 retinal rod cell differentiation 1/244 12/18722 0.14569600487499 0.356748935930863 NAGLU 1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 1/244 12/18722 0.14569600487499 0.356748935930863 LRP1 1 GO:0060442 branching involved in prostate gland morphogenesis 1/244 12/18722 0.14569600487499 0.356748935930863 BMP7 1 GO:0060601 lateral sprouting from an epithelium 1/244 12/18722 0.14569600487499 0.356748935930863 BMP7 1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1/244 12/18722 0.14569600487499 0.356748935930863 GLI3 1 GO:0061430 bone trabecula morphogenesis 1/244 12/18722 0.14569600487499 0.356748935930863 FBN2 1 GO:0070572 positive regulation of neuron projection regeneration 1/244 12/18722 0.14569600487499 0.356748935930863 LRP1 1 GO:0071107 response to parathyroid hormone 1/244 12/18722 0.14569600487499 0.356748935930863 GJA1 1 GO:0071635 negative regulation of transforming growth factor beta production 1/244 12/18722 0.14569600487499 0.356748935930863 TSKU 1 GO:0071872 cellular response to epinephrine stimulus 1/244 12/18722 0.14569600487499 0.356748935930863 ATP2B4 1 GO:0086067 AV node cell to bundle of His cell communication 1/244 12/18722 0.14569600487499 0.356748935930863 GJA5 1 GO:0090331 negative regulation of platelet aggregation 1/244 12/18722 0.14569600487499 0.356748935930863 SERPINE2 1 GO:0097152 mesenchymal cell apoptotic process 1/244 12/18722 0.14569600487499 0.356748935930863 BMP7 1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress 1/244 12/18722 0.14569600487499 0.356748935930863 JUN 1 GO:0098974 postsynaptic actin cytoskeleton organization 1/244 12/18722 0.14569600487499 0.356748935930863 PPP1R9A 1 GO:0120263 positive regulation of heterochromatin organization 1/244 12/18722 0.14569600487499 0.356748935930863 MPHOSPH8 1 GO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus 1/244 12/18722 0.14569600487499 0.356748935930863 MIA3 1 GO:1901298 regulation of hydrogen peroxide-mediated programmed cell death 1/244 12/18722 0.14569600487499 0.356748935930863 MET 1 GO:1903332 regulation of protein folding 1/244 12/18722 0.14569600487499 0.356748935930863 HSPA5 1 GO:1903599 positive regulation of autophagy of mitochondrion 1/244 12/18722 0.14569600487499 0.356748935930863 HTT 1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA 1/244 12/18722 0.14569600487499 0.356748935930863 DDX5 1 GO:2000628 regulation of miRNA metabolic process 1/244 12/18722 0.14569600487499 0.356748935930863 KCNQ1OT1 1 GO:2001204 regulation of osteoclast development 1/244 12/18722 0.14569600487499 0.356748935930863 FBN1 1 GO:0001505 regulation of neurotransmitter levels 5/244 213/18722 0.146265302573317 0.357876235484676 PPP1R9A/SLC6A4/CALM1/ITGB1/SLC1A3 5 GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 2/244 52/18722 0.147194912052257 0.358283319262012 HTT/PLPP3 2 GO:0030514 negative regulation of BMP signaling pathway 2/244 52/18722 0.147194912052257 0.358283319262012 LRP2/FBN1 2 GO:0035176 social behavior 2/244 52/18722 0.147194912052257 0.358283319262012 NLGN4X/SLC6A4 2 GO:0035196 production of miRNAs involved in gene silencing by miRNA 2/244 52/18722 0.147194912052257 0.358283319262012 PUM1/DDX5 2 GO:0043090 amino acid import 2/244 52/18722 0.147194912052257 0.358283319262012 ITGB1/SLC1A3 2 GO:0043277 apoptotic cell clearance 2/244 52/18722 0.147194912052257 0.358283319262012 LRP1/ITGAV 2 GO:0045103 intermediate filament-based process 2/244 52/18722 0.147194912052257 0.358283319262012 DST/MACF1 2 GO:0006672 ceramide metabolic process 3/244 102/18722 0.148222955407089 0.359985684750699 ITGB8/ASAH1/PLPP3 3 GO:0010522 regulation of calcium ion transport into cytosol 3/244 102/18722 0.148222955407089 0.359985684750699 CALM1/P2RY6/HTT 3 GO:0014897 striated muscle hypertrophy 3/244 102/18722 0.148222955407089 0.359985684750699 IL6ST/JARID2/ATP2B4 3 GO:0009410 response to xenobiotic stimulus 9/244 462/18722 0.150998762494915 0.363702724529126 JUN/NCEH1/SLC6A4/LDHA/HSPA5/CDH1/RPN2/DNMT3A/SLC1A3 9 GO:0009135 purine nucleoside diphosphate metabolic process 3/244 103/18722 0.151295120281332 0.363702724529126 APP/LDHA/GAPDH 3 GO:0009179 purine ribonucleoside diphosphate metabolic process 3/244 103/18722 0.151295120281332 0.363702724529126 APP/LDHA/GAPDH 3 GO:0030148 sphingolipid biosynthetic process 3/244 103/18722 0.151295120281332 0.363702724529126 HACD3/ASAH1/PLPP3 3 GO:0090277 positive regulation of peptide hormone secretion 3/244 103/18722 0.151295120281332 0.363702724529126 LRP1/ISL1/GJA1 3 GO:0007566 embryo implantation 2/244 53/18722 0.15172112625492 0.363702724529126 ITGB4/GJA1 2 GO:0043620 regulation of DNA-templated transcription in response to stress 2/244 53/18722 0.15172112625492 0.363702724529126 JUN/HSPA5 2 GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 2/244 53/18722 0.15172112625492 0.363702724529126 MET/ATP2B4 2 GO:0099172 presynapse organization 2/244 53/18722 0.15172112625492 0.363702724529126 NLGN4X/APP 2 GO:0035966 response to topologically incorrect protein 4/244 159/18722 0.154241528561483 0.363702724529126 TBL2/HSPA5/SERPINH1/DNAJB14 4 GO:0046488 phosphatidylinositol metabolic process 4/244 159/18722 0.154241528561483 0.363702724529126 CDS1/PGAP1/SACM1L/PIP5K1B 4 GO:0051170 import into nucleus 4/244 159/18722 0.154241528561483 0.363702724529126 FAM53C/GLI3/CDH1/HYAL2 4 GO:0014896 muscle hypertrophy 3/244 104/18722 0.154387567283495 0.363702724529126 IL6ST/JARID2/ATP2B4 3 GO:0008154 actin polymerization or depolymerization 5/244 217/18722 0.15441820026067 0.363702724529126 SVIL/PPP1R9A/KANK1/IQGAP2/SPTBN1 5 GO:0048545 response to steroid hormone 7/244 339/18722 0.15548230201062 0.363702724529126 ISL1/ATP2B1/BMP7/CALM1/CLDN4/CTSV/DDX5 7 GO:0006968 cellular defense response 2/244 54/18722 0.156274582934402 0.363702724529126 LGALS3BP/ITGB1 2 GO:0007215 glutamate receptor signaling pathway 2/244 54/18722 0.156274582934402 0.363702724529126 APP/GNAQ 2 GO:0030520 intracellular estrogen receptor signaling pathway 2/244 54/18722 0.156274582934402 0.363702724529126 ISL1/DDX5 2 GO:0030834 regulation of actin filament depolymerization 2/244 54/18722 0.156274582934402 0.363702724529126 SVIL/SPTBN1 2 GO:0031050 dsRNA processing 2/244 54/18722 0.156274582934402 0.363702724529126 PUM1/DDX5 2 GO:0032330 regulation of chondrocyte differentiation 2/244 54/18722 0.156274582934402 0.363702724529126 GLI3/EFEMP1 2 GO:0051703 biological process involved in intraspecies interaction between organisms 2/244 54/18722 0.156274582934402 0.363702724529126 NLGN4X/SLC6A4 2 GO:0070918 production of small RNA involved in gene silencing by RNA 2/244 54/18722 0.156274582934402 0.363702724529126 PUM1/DDX5 2 GO:2000179 positive regulation of neural precursor cell proliferation 2/244 54/18722 0.156274582934402 0.363702724529126 LRP2/GLI3 2 GO:0001886 endothelial cell morphogenesis 1/244 13/18722 0.156837115233649 0.363702724529126 MET 1 GO:0003334 keratinocyte development 1/244 13/18722 0.156837115233649 0.363702724529126 PALLD 1 GO:0006983 ER overload response 1/244 13/18722 0.156837115233649 0.363702724529126 HSPA5 1 GO:0009650 UV protection 1/244 13/18722 0.156837115233649 0.363702724529126 SCARA3 1 GO:0010635 regulation of mitochondrial fusion 1/244 13/18722 0.156837115233649 0.363702724529126 HUWE1 1 GO:0010745 negative regulation of macrophage derived foam cell differentiation 1/244 13/18722 0.156837115233649 0.363702724529126 ITGAV 1 GO:0010755 regulation of plasminogen activation 1/244 13/18722 0.156837115233649 0.363702724529126 SERPINE2 1 GO:0010958 regulation of amino acid import across plasma membrane 1/244 13/18722 0.156837115233649 0.363702724529126 ITGB1 1 GO:0014745 negative regulation of muscle adaptation 1/244 13/18722 0.156837115233649 0.363702724529126 ATP2B4 1 GO:0015809 arginine transport 1/244 13/18722 0.156837115233649 0.363702724529126 SLC38A9 1 GO:0016024 CDP-diacylglycerol biosynthetic process 1/244 13/18722 0.156837115233649 0.363702724529126 CDS1 1 GO:0016322 neuron remodeling 1/244 13/18722 0.156837115233649 0.363702724529126 APP 1 GO:0021514 ventral spinal cord interneuron differentiation 1/244 13/18722 0.156837115233649 0.363702724529126 GLI3 1 GO:0021554 optic nerve development 1/244 13/18722 0.156837115233649 0.363702724529126 GLI3 1 GO:0021681 cerebellar granular layer development 1/244 13/18722 0.156837115233649 0.363702724529126 SERPINE2 1 GO:0021819 layer formation in cerebral cortex 1/244 13/18722 0.156837115233649 0.363702724529126 GLI3 1 GO:0030497 fatty acid elongation 1/244 13/18722 0.156837115233649 0.363702724529126 HACD3 1 GO:0032429 regulation of phospholipase A2 activity 1/244 13/18722 0.156837115233649 0.363702724529126 LRP1 1 GO:0032905 transforming growth factor beta1 production 1/244 13/18722 0.156837115233649 0.363702724529126 TSKU 1 GO:0034112 positive regulation of homotypic cell-cell adhesion 1/244 13/18722 0.156837115233649 0.363702724529126 IL6ST 1 GO:0035331 negative regulation of hippo signaling 1/244 13/18722 0.156837115233649 0.363702724529126 WWC1 1 GO:0042761 very long-chain fatty acid biosynthetic process 1/244 13/18722 0.156837115233649 0.363702724529126 HACD3 1 GO:0046415 urate metabolic process 1/244 13/18722 0.156837115233649 0.363702724529126 SLC22A11 1 GO:0046512 sphingosine biosynthetic process 1/244 13/18722 0.156837115233649 0.363702724529126 ASAH1 1 GO:0046520 sphingoid biosynthetic process 1/244 13/18722 0.156837115233649 0.363702724529126 ASAH1 1 GO:0048012 hepatocyte growth factor receptor signaling pathway 1/244 13/18722 0.156837115233649 0.363702724529126 MET 1 GO:0048266 behavioral response to pain 1/244 13/18722 0.156837115233649 0.363702724529126 VWA1 1 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 1/244 13/18722 0.156837115233649 0.363702724529126 CALM1 1 GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1/244 13/18722 0.156837115233649 0.363702724529126 TNRC6B 1 GO:0060670 branching involved in labyrinthine layer morphogenesis 1/244 13/18722 0.156837115233649 0.363702724529126 SPINT1 1 GO:0060707 trophoblast giant cell differentiation 1/244 13/18722 0.156837115233649 0.363702724529126 NR2F2 1 GO:0061744 motor behavior 1/244 13/18722 0.156837115233649 0.363702724529126 DPP4 1 GO:0070486 leukocyte aggregation 1/244 13/18722 0.156837115233649 0.363702724529126 BMP7 1 GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 1/244 13/18722 0.156837115233649 0.363702724529126 ATP2B4 1 GO:1900452 regulation of long-term synaptic depression 1/244 13/18722 0.156837115233649 0.363702724529126 PPP1R9A 1 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance 1/244 13/18722 0.156837115233649 0.363702724529126 NRP2 1 GO:1903789 regulation of amino acid transmembrane transport 1/244 13/18722 0.156837115233649 0.363702724529126 ITGB1 1 GO:1903977 positive regulation of glial cell migration 1/244 13/18722 0.156837115233649 0.363702724529126 LRP1 1 GO:1904925 positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization 1/244 13/18722 0.156837115233649 0.363702724529126 HUWE1 1 GO:1905269 positive regulation of chromatin organization 1/244 13/18722 0.156837115233649 0.363702724529126 MPHOSPH8 1 GO:0032231 regulation of actin filament bundle assembly 3/244 105/18722 0.157499835534392 0.364981988410446 PPP1R9A/TACSTD2/MET 3 GO:0071805 potassium ion transmembrane transport 5/244 219/18722 0.158564443834248 0.3671901074273 KCNN4/AKAP9/ITGB1/SLC12A9/SLC1A3 5 GO:0002793 positive regulation of peptide secretion 3/244 106/18722 0.16063146506849 0.368852495754571 LRP1/ISL1/GJA1 3 GO:0006090 pyruvate metabolic process 3/244 106/18722 0.16063146506849 0.368852495754571 APP/LDHA/GAPDH 3 GO:0009185 ribonucleoside diphosphate metabolic process 3/244 106/18722 0.16063146506849 0.368852495754571 APP/LDHA/GAPDH 3 GO:0019882 antigen processing and presentation 3/244 106/18722 0.16063146506849 0.368852495754571 CTSL/CTSV/LGMN 3 GO:0030038 contractile actin filament bundle assembly 3/244 106/18722 0.16063146506849 0.368852495754571 PPP1R9A/TACSTD2/MET 3 GO:0035821 modulation of process of other organism 3/244 106/18722 0.16063146506849 0.368852495754571 JUN/DAG1/HYAL2 3 GO:0043149 stress fiber assembly 3/244 106/18722 0.16063146506849 0.368852495754571 PPP1R9A/TACSTD2/MET 3 GO:0046822 regulation of nucleocytoplasmic transport 3/244 106/18722 0.16063146506849 0.368852495754571 GLI3/CDH1/HYAL2 3 GO:0071887 leukocyte apoptotic process 3/244 106/18722 0.16063146506849 0.368852495754571 CTSL/SLC39A10/GLI3 3 GO:0099565 chemical synaptic transmission, postsynaptic 3/244 106/18722 0.16063146506849 0.368852495754571 NLGN4X/PPP1R9A/APP 3 GO:0031113 regulation of microtubule polymerization 2/244 55/18722 0.160853812056086 0.368852495754571 MET/AKAP9 2 GO:0044091 membrane biogenesis 2/244 55/18722 0.160853812056086 0.368852495754571 NLGN4X/SPTBN1 2 GO:0048016 inositol phosphate-mediated signaling 2/244 55/18722 0.160853812056086 0.368852495754571 RCAN1/ATP2B4 2 GO:0051898 negative regulation of protein kinase B signaling 2/244 55/18722 0.160853812056086 0.368852495754571 DAG1/HYAL2 2 GO:0021953 central nervous system neuron differentiation 4/244 162/18722 0.161638875278244 0.370394242792406 NRP2/ISL1/GLI3/TSKU 4 GO:0006470 protein dephosphorylation 6/244 281/18722 0.161859655319911 0.370641691554863 NCEH1/SLC39A10/CALM1/RCAN1/HTT/CTDSPL 6 GO:0010518 positive regulation of phospholipase activity 2/244 56/18722 0.165457376983684 0.371631366555703 P2RY6/GNAQ 2 GO:0022029 telencephalon cell migration 2/244 56/18722 0.165457376983684 0.371631366555703 LAMB1/GLI3 2 GO:0031529 ruffle organization 2/244 56/18722 0.165457376983684 0.371631366555703 KANK1/TACSTD2 2 GO:0042733 embryonic digit morphogenesis 2/244 56/18722 0.165457376983684 0.371631366555703 LRP5/GLI3 2 GO:0071385 cellular response to glucocorticoid stimulus 2/244 56/18722 0.165457376983684 0.371631366555703 ISL1/ATP2B1 2 GO:0050680 negative regulation of epithelial cell proliferation 4/244 164/18722 0.16664138685109 0.371631366555703 NR2F2/ISL1/GJA1/TGFBR3 4 GO:0050792 regulation of viral process 4/244 164/18722 0.16664138685109 0.371631366555703 MPHOSPH8/HACD3/P4HB/DDX5 4 GO:0033138 positive regulation of peptidyl-serine phosphorylation 3/244 108/18722 0.166950973595628 0.371631366555703 APP/AKAP9/ATP2B4 3 GO:0098659 inorganic cation import across plasma membrane 3/244 108/18722 0.166950973595628 0.371631366555703 SLC39A10/ATP2B4/SLC12A9 3 GO:0099587 inorganic ion import across plasma membrane 3/244 108/18722 0.166950973595628 0.371631366555703 SLC39A10/ATP2B4/SLC12A9 3 GO:0050920 regulation of chemotaxis 5/244 223/18722 0.166991878800933 0.371631366555703 SEMA6A/SEMA6D/MET/DPP4/LGMN 5 GO:0022409 positive regulation of cell-cell adhesion 6/244 284/18722 0.167434630117713 0.371631366555703 IL6ST/BMP7/DPP4/GLI3/PLPP3/GCNT2 6 GO:0003188 heart valve formation 1/244 14/18722 0.167833520379995 0.371631366555703 GJA5 1 GO:0006521 regulation of cellular amino acid metabolic process 1/244 14/18722 0.167833520379995 0.371631366555703 ATP2B4 1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity 1/244 14/18722 0.167833520379995 0.371631366555703 EFNA5 1 GO:0009071 serine family amino acid catabolic process 1/244 14/18722 0.167833520379995 0.371631366555703 GLDC 1 GO:0010421 hydrogen peroxide-mediated programmed cell death 1/244 14/18722 0.167833520379995 0.371631366555703 MET 1 GO:0014874 response to stimulus involved in regulation of muscle adaptation 1/244 14/18722 0.167833520379995 0.371631366555703 DAG1 1 GO:0022038 corpus callosum development 1/244 14/18722 0.167833520379995 0.371631366555703 TSKU 1 GO:0034111 negative regulation of homotypic cell-cell adhesion 1/244 14/18722 0.167833520379995 0.371631366555703 SERPINE2 1 GO:0034616 response to laminar fluid shear stress 1/244 14/18722 0.167833520379995 0.371631366555703 SREBF2 1 GO:0035589 G protein-coupled purinergic nucleotide receptor signaling pathway 1/244 14/18722 0.167833520379995 0.371631366555703 P2RY6 1 GO:0035641 locomotory exploration behavior 1/244 14/18722 0.167833520379995 0.371631366555703 DPP4 1 GO:0035672 oligopeptide transmembrane transport 1/244 14/18722 0.167833520379995 0.371631366555703 GJA1 1 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway 1/244 14/18722 0.167833520379995 0.371631366555703 LRP1 1 GO:0035810 positive regulation of urine volume 1/244 14/18722 0.167833520379995 0.371631366555703 HYAL2 1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 1/244 14/18722 0.167833520379995 0.371631366555703 DDX5 1 GO:0043922 negative regulation by host of viral transcription 1/244 14/18722 0.167833520379995 0.371631366555703 JUN 1 GO:0046341 CDP-diacylglycerol metabolic process 1/244 14/18722 0.167833520379995 0.371631366555703 CDS1 1 GO:0051589 negative regulation of neurotransmitter transport 1/244 14/18722 0.167833520379995 0.371631366555703 PPP1R9A 1 GO:0060576 intestinal epithelial cell development 1/244 14/18722 0.167833520379995 0.371631366555703 IL6ST 1 GO:0060732 positive regulation of inositol phosphate biosynthetic process 1/244 14/18722 0.167833520379995 0.371631366555703 P2RY6 1 GO:0060911 cardiac cell fate commitment 1/244 14/18722 0.167833520379995 0.371631366555703 ISL1 1 GO:0071236 cellular response to antibiotic 1/244 14/18722 0.167833520379995 0.371631366555703 HSPA5 1 GO:0071285 cellular response to lithium ion 1/244 14/18722 0.167833520379995 0.371631366555703 CDH1 1 GO:0071415 cellular response to purine-containing compound 1/244 14/18722 0.167833520379995 0.371631366555703 P2RY6 1 GO:0072498 embryonic skeletal joint development 1/244 14/18722 0.167833520379995 0.371631366555703 BMP7 1 GO:0072531 pyrimidine-containing compound transmembrane transport 1/244 14/18722 0.167833520379995 0.371631366555703 SLC19A3 1 GO:0086103 G protein-coupled receptor signaling pathway involved in heart process 1/244 14/18722 0.167833520379995 0.371631366555703 ATP2B4 1 GO:0090308 regulation of DNA methylation-dependent heterochromatin assembly 1/244 14/18722 0.167833520379995 0.371631366555703 MPHOSPH8 1 GO:0099188 postsynaptic cytoskeleton organization 1/244 14/18722 0.167833520379995 0.371631366555703 PPP1R9A 1 GO:1901678 iron coordination entity transport 1/244 14/18722 0.167833520379995 0.371631366555703 SLC46A1 1 GO:1901722 regulation of cell proliferation involved in kidney development 1/244 14/18722 0.167833520379995 0.371631366555703 BMP7 1 GO:1902036 regulation of hematopoietic stem cell differentiation 1/244 14/18722 0.167833520379995 0.371631366555703 FOXC1 1 GO:1903894 regulation of IRE1-mediated unfolded protein response 1/244 14/18722 0.167833520379995 0.371631366555703 HSPA5 1 GO:1904152 regulation of retrograde protein transport, ER to cytosol 1/244 14/18722 0.167833520379995 0.371631366555703 SVIP 1 GO:1904923 regulation of autophagy of mitochondrion in response to mitochondrial depolarization 1/244 14/18722 0.167833520379995 0.371631366555703 HUWE1 1 GO:1905049 negative regulation of metallopeptidase activity 1/244 14/18722 0.167833520379995 0.371631366555703 LRP1 1 GO:2001256 regulation of store-operated calcium entry 1/244 14/18722 0.167833520379995 0.371631366555703 STIM1 1 GO:0002011 morphogenesis of an epithelial sheet 2/244 57/18722 0.17008387386441 0.375216957124522 BMP7/DAG1 2 GO:0010883 regulation of lipid storage 2/244 57/18722 0.17008387386441 0.375216957124522 ITGAV/SREBF2 2 GO:0060042 retina morphogenesis in camera-type eye 2/244 57/18722 0.17008387386441 0.375216957124522 LRP5/NAGLU 2 GO:0061005 cell differentiation involved in kidney development 2/244 57/18722 0.17008387386441 0.375216957124522 LGR4/GLI3 2 GO:1902017 regulation of cilium assembly 2/244 57/18722 0.17008387386441 0.375216957124522 DZIP1/HTT 2 GO:0043266 regulation of potassium ion transport 3/244 109/18722 0.170137938562245 0.375216957124522 KCNN4/AKAP9/ITGB1 3 GO:0043112 receptor metabolic process 4/244 166/18722 0.171698678307001 0.378405001285584 LRP1/ITGB1/FUT8/LGMN 4 GO:0031960 response to corticosteroid 4/244 167/18722 0.174247332729674 0.381559278134508 ISL1/ATP2B1/CALM1/CTSV 4 GO:0043434 response to peptide hormone 8/244 414/18722 0.174361406179661 0.381559278134508 FBN1/LRP5/KANK1/ATP2B1/BMP7/DAG1/GJA1/TGFBR3 8 GO:0001954 positive regulation of cell-matrix adhesion 2/244 58/18722 0.174731931024407 0.381559278134508 UTRN/DAG1 2 GO:0002931 response to ischemia 2/244 58/18722 0.174731931024407 0.381559278134508 GJA1/RCAN1 2 GO:0010574 regulation of vascular endothelial growth factor production 2/244 58/18722 0.174731931024407 0.381559278134508 IL6ST/ISL1 2 GO:0018208 peptidyl-proline modification 2/244 58/18722 0.174731931024407 0.381559278134508 P3H2/P4HB 2 GO:0032387 negative regulation of intracellular transport 2/244 58/18722 0.174731931024407 0.381559278134508 LMAN1/SVIP 2 GO:0035904 aorta development 2/244 58/18722 0.174731931024407 0.381559278134508 LRP2/LRP1 2 GO:2000736 regulation of stem cell differentiation 2/244 58/18722 0.174731931024407 0.381559278134508 TACSTD2/FOXC1 2 GO:0034599 cellular response to oxidative stress 6/244 288/18722 0.174992569698462 0.381559278134508 JUN/BMP7/SOD3/MET/FUT8/P4HB 6 GO:0099173 postsynapse organization 4/244 168/18722 0.176809040230925 0.381559278134508 NLGN4X/NRP2/PPP1R9A/LGMN 4 GO:0006089 lactate metabolic process 1/244 15/18722 0.178687092168924 0.381559278134508 LDHA 1 GO:0006878 cellular copper ion homeostasis 1/244 15/18722 0.178687092168924 0.381559278134508 APP 1 GO:0010713 negative regulation of collagen metabolic process 1/244 15/18722 0.178687092168924 0.381559278134508 CST3 1 GO:0010763 positive regulation of fibroblast migration 1/244 15/18722 0.178687092168924 0.381559278134508 ITGB1 1 GO:0023035 CD40 signaling pathway 1/244 15/18722 0.178687092168924 0.381559278134508 ITGB1 1 GO:0032354 response to follicle-stimulating hormone 1/244 15/18722 0.178687092168924 0.381559278134508 TGFBR3 1 GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 1/244 15/18722 0.178687092168924 0.381559278134508 ISL1 1 GO:0032933 SREBP signaling pathway 1/244 15/18722 0.178687092168924 0.381559278134508 SREBF2 1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway 1/244 15/18722 0.178687092168924 0.381559278134508 ISL1 1 GO:0035627 ceramide transport 1/244 15/18722 0.178687092168924 0.381559278134508 PLEKHA8 1 GO:0043584 nose development 1/244 15/18722 0.178687092168924 0.381559278134508 GLI3 1 GO:0043981 histone H4-K5 acetylation 1/244 15/18722 0.178687092168924 0.381559278134508 PHF20 1 GO:0043982 histone H4-K8 acetylation 1/244 15/18722 0.178687092168924 0.381559278134508 PHF20 1 GO:0045475 locomotor rhythm 1/244 15/18722 0.178687092168924 0.381559278134508 NAGLU 1 GO:0046459 short-chain fatty acid metabolic process 1/244 15/18722 0.178687092168924 0.381559278134508 ACSS1 1 GO:0051284 positive regulation of sequestering of calcium ion 1/244 15/18722 0.178687092168924 0.381559278134508 CALM1 1 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 1/244 15/18722 0.178687092168924 0.381559278134508 TNRC6B 1 GO:0060413 atrial septum morphogenesis 1/244 15/18722 0.178687092168924 0.381559278134508 ISL1 1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport 1/244 15/18722 0.178687092168924 0.381559278134508 PGAP1 1 GO:0070071 proton-transporting two-sector ATPase complex assembly 1/244 15/18722 0.178687092168924 0.381559278134508 ATP6V1B1 1 GO:0071380 cellular response to prostaglandin E stimulus 1/244 15/18722 0.178687092168924 0.381559278134508 P2RY6 1 GO:0071871 response to epinephrine 1/244 15/18722 0.178687092168924 0.381559278134508 ATP2B4 1 GO:0072075 metanephric mesenchyme development 1/244 15/18722 0.178687092168924 0.381559278134508 BMP7 1 GO:0072224 metanephric glomerulus development 1/244 15/18722 0.178687092168924 0.381559278134508 LGR4 1 GO:0090110 COPII-coated vesicle cargo loading 1/244 15/18722 0.178687092168924 0.381559278134508 MIA3 1 GO:0097468 programmed cell death in response to reactive oxygen species 1/244 15/18722 0.178687092168924 0.381559278134508 MET 1 GO:0099170 postsynaptic modulation of chemical synaptic transmission 1/244 15/18722 0.178687092168924 0.381559278134508 CDH1 1 GO:0150011 regulation of neuron projection arborization 1/244 15/18722 0.178687092168924 0.381559278134508 MACF1 1 GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response 1/244 15/18722 0.178687092168924 0.381559278134508 HSPA5 1 GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1/244 15/18722 0.178687092168924 0.381559278134508 TNRC6B 1 GO:1901841 regulation of high voltage-gated calcium channel activity 1/244 15/18722 0.178687092168924 0.381559278134508 CALM1 1 GO:1904424 regulation of GTP binding 1/244 15/18722 0.178687092168924 0.381559278134508 MET 1 GO:1904874 positive regulation of telomerase RNA localization to Cajal body 1/244 15/18722 0.178687092168924 0.381559278134508 NAF1 1 GO:1990822 basic amino acid transmembrane transport 1/244 15/18722 0.178687092168924 0.381559278134508 SLC38A9 1 GO:2000402 negative regulation of lymphocyte migration 1/244 15/18722 0.178687092168924 0.381559278134508 MIA3 1 GO:0034504 protein localization to nucleus 6/244 290/18722 0.178823552965413 0.381559278134508 LATS2/BMP7/FAM53C/GLI3/CDH1/HYAL2 6 GO:0016311 dephosphorylation 8/244 417/18722 0.179101568449174 0.381559278134508 NCEH1/SLC39A10/CALM1/SACM1L/RCAN1/HTT/PLPP3/CTDSPL 8 GO:0021885 forebrain cell migration 2/244 59/18722 0.179400208374259 0.381559278134508 LAMB1/GLI3 2 GO:0030042 actin filament depolymerization 2/244 59/18722 0.179400208374259 0.381559278134508 SVIL/SPTBN1 2 GO:0032768 regulation of monooxygenase activity 2/244 59/18722 0.179400208374259 0.381559278134508 CALM1/ATP2B4 2 GO:0033013 tetrapyrrole metabolic process 2/244 59/18722 0.179400208374259 0.381559278134508 SLC46A1/MTR 2 GO:0035306 positive regulation of dephosphorylation 2/244 59/18722 0.179400208374259 0.381559278134508 SLC39A10/CALM1 2 GO:0043407 negative regulation of MAP kinase activity 2/244 59/18722 0.179400208374259 0.381559278134508 BMP7/HYAL2 2 GO:0010633 negative regulation of epithelial cell migration 3/244 112/18722 0.179802223330006 0.382166950751876 NR2F2/TACSTD2/ATP2B4 3 GO:0045444 fat cell differentiation 5/244 229/18722 0.179956039296724 0.38224663550681 LRP5/ADRB1/BMP7/CDS1/ANKRD26 5 GO:0006893 Golgi to plasma membrane transport 2/244 60/18722 0.184087396824425 0.387719643801503 MACF1/SPTBN1 2 GO:0033866 nucleoside bisphosphate biosynthetic process 2/244 60/18722 0.184087396824425 0.387719643801503 SLC26A2/ACSS1 2 GO:0034030 ribonucleoside bisphosphate biosynthetic process 2/244 60/18722 0.184087396824425 0.387719643801503 SLC26A2/ACSS1 2 GO:0034033 purine nucleoside bisphosphate biosynthetic process 2/244 60/18722 0.184087396824425 0.387719643801503 SLC26A2/ACSS1 2 GO:0061951 establishment of protein localization to plasma membrane 2/244 60/18722 0.184087396824425 0.387719643801503 MACF1/SPTBN1 2 GO:0045732 positive regulation of protein catabolic process 5/244 231/18722 0.184359641498059 0.387719643801503 LRP2/LRP1/GJA1/HUWE1/TMTC3 5 GO:0051048 negative regulation of secretion 4/244 171/18722 0.184570325625143 0.387719643801503 PPP1R9A/ERP29/GJA1/RAB11FIP1 4 GO:0002244 hematopoietic progenitor cell differentiation 3/244 114/18722 0.186326728302818 0.387719643801503 PRRC2C/FOXC1/HYAL2 3 GO:0019751 polyol metabolic process 3/244 114/18722 0.186326728302818 0.387719643801503 P2RY6/ASAH1/PLPP3 3 GO:0021987 cerebral cortex development 3/244 114/18722 0.186326728302818 0.387719643801503 LRP1/LAMB1/GLI3 3 GO:1903008 organelle disassembly 3/244 114/18722 0.186326728302818 0.387719643801503 HUWE1/HTT/SREBF2 3 GO:0071384 cellular response to corticosteroid stimulus 2/244 61/18722 0.188792217710448 0.387719643801503 ISL1/ATP2B1 2 GO:2000401 regulation of lymphocyte migration 2/244 61/18722 0.188792217710448 0.387719643801503 APP/MIA3 2 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 5/244 233/18722 0.188802684521537 0.387719643801503 LGR5/ADRB1/ATP2B4/LGR4/GNAQ 5 GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin 1/244 16/18722 0.189399678340452 0.387719643801503 ENPEP 1 GO:0003084 positive regulation of systemic arterial blood pressure 1/244 16/18722 0.189399678340452 0.387719643801503 NR2F2 1 GO:0006004 fucose metabolic process 1/244 16/18722 0.189399678340452 0.387719643801503 FUT8 1 GO:0006349 regulation of gene expression by genetic imprinting 1/244 16/18722 0.189399678340452 0.387719643801503 DNMT3A 1 GO:0006544 glycine metabolic process 1/244 16/18722 0.189399678340452 0.387719643801503 GLDC 1 GO:0006555 methionine metabolic process 1/244 16/18722 0.189399678340452 0.387719643801503 MTR 1 GO:0006857 oligopeptide transport 1/244 16/18722 0.189399678340452 0.387719643801503 GJA1 1 GO:0007635 chemosensory behavior 1/244 16/18722 0.189399678340452 0.387719643801503 ATP6V1B1 1 GO:0009299 mRNA transcription 1/244 16/18722 0.189399678340452 0.387719643801503 DDX5 1 GO:0009415 response to water 1/244 16/18722 0.189399678340452 0.387719643801503 ATP2B4 1 GO:0010919 regulation of inositol phosphate biosynthetic process 1/244 16/18722 0.189399678340452 0.387719643801503 P2RY6 1 GO:0021783 preganglionic parasympathetic fiber development 1/244 16/18722 0.189399678340452 0.387719643801503 NRP2 1 GO:0030540 female genitalia development 1/244 16/18722 0.189399678340452 0.387719643801503 LRP2 1 GO:0030575 nuclear body organization 1/244 16/18722 0.189399678340452 0.387719643801503 SF1 1 GO:0032274 gonadotropin secretion 1/244 16/18722 0.189399678340452 0.387719643801503 GJA1 1 GO:0043923 positive regulation by host of viral transcription 1/244 16/18722 0.189399678340452 0.387719643801503 JUN 1 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate 1/244 16/18722 0.189399678340452 0.387719643801503 MPHOSPH8 1 GO:0048557 embryonic digestive tract morphogenesis 1/244 16/18722 0.189399678340452 0.387719643801503 GLI3 1 GO:0050862 positive regulation of T cell receptor signaling pathway 1/244 16/18722 0.189399678340452 0.387719643801503 KCNN4 1 GO:0050884 neuromuscular process controlling posture 1/244 16/18722 0.189399678340452 0.387719643801503 TMEM150C 1 GO:0051014 actin filament severing 1/244 16/18722 0.189399678340452 0.387719643801503 SVIL 1 GO:0060572 morphogenesis of an epithelial bud 1/244 16/18722 0.189399678340452 0.387719643801503 BMP7 1 GO:0061548 ganglion development 1/244 16/18722 0.189399678340452 0.387719643801503 NRP2 1 GO:0070242 thymocyte apoptotic process 1/244 16/18722 0.189399678340452 0.387719643801503 GLI3 1 GO:0071361 cellular response to ethanol 1/244 16/18722 0.189399678340452 0.387719643801503 DNMT3A 1 GO:0071501 cellular response to sterol depletion 1/244 16/18722 0.189399678340452 0.387719643801503 SREBF2 1 GO:0071732 cellular response to nitric oxide 1/244 16/18722 0.189399678340452 0.387719643801503 MTR 1 GO:0072109 glomerular mesangium development 1/244 16/18722 0.189399678340452 0.387719643801503 BMP7 1 GO:0072148 epithelial cell fate commitment 1/244 16/18722 0.189399678340452 0.387719643801503 NR2F2 1 GO:0090336 positive regulation of brown fat cell differentiation 1/244 16/18722 0.189399678340452 0.387719643801503 BMP7 1 GO:0097202 activation of cysteine-type endopeptidase activity 1/244 16/18722 0.189399678340452 0.387719643801503 LGMN 1 GO:0097284 hepatocyte apoptotic process 1/244 16/18722 0.189399678340452 0.387719643801503 DNMT3A 1 GO:0099010 modification of postsynaptic structure 1/244 16/18722 0.189399678340452 0.387719643801503 MYH10 1 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration 1/244 16/18722 0.189399678340452 0.387719643801503 ATP2B1 1 GO:0099633 protein localization to postsynaptic specialization membrane 1/244 16/18722 0.189399678340452 0.387719643801503 DAG1 1 GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane 1/244 16/18722 0.189399678340452 0.387719643801503 DAG1 1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway 1/244 16/18722 0.189399678340452 0.387719643801503 SEMA6A 1 GO:1901163 regulation of trophoblast cell migration 1/244 16/18722 0.189399678340452 0.387719643801503 GJA1 1 GO:1901201 regulation of extracellular matrix assembly 1/244 16/18722 0.189399678340452 0.387719643801503 DAG1 1 GO:1905906 regulation of amyloid fibril formation 1/244 16/18722 0.189399678340452 0.387719643801503 APP 1 GO:2001224 positive regulation of neuron migration 1/244 16/18722 0.189399678340452 0.387719643801503 SEMA6A 1 GO:1901653 cellular response to peptide 7/244 359/18722 0.189571230847237 0.387719643801503 FBN1/LRP1/KANK1/ATP2B1/APP/GJA1/LGMN 7 GO:0043279 response to alkaloid 3/244 115/18722 0.189612132559043 0.387719643801503 HSPA5/DNMT3A/SLC1A3 3 GO:0046916 cellular transition metal ion homeostasis 3/244 115/18722 0.189612132559043 0.387719643801503 SLC39A10/APP/SLC46A1 3 GO:0071675 regulation of mononuclear cell migration 3/244 115/18722 0.189612132559043 0.387719643801503 APP/MIA3/LGMN 3 GO:1901989 positive regulation of cell cycle phase transition 3/244 115/18722 0.189612132559043 0.387719643801503 ADAMTS1/APP/PBX1 3 GO:0010498 proteasomal protein catabolic process 9/244 490/18722 0.191325384624249 0.390979610618956 RNF216/HSPA5/HUWE1/TMTC3/TBL1X/NEMF/USP25/SVIP/DNAJB14 9 GO:0048639 positive regulation of developmental growth 4/244 174/18722 0.192441308981549 0.392037672897964 LRP1/MACF1/TGFBR3/HOPX 4 GO:0006720 isoprenoid metabolic process 3/244 116/18722 0.192912379480832 0.392037672897964 LRP2/LRP1/RDH14 3 GO:0018107 peptidyl-threonine phosphorylation 3/244 116/18722 0.192912379480832 0.392037672897964 BMP7/APP/CALM1 3 GO:0035967 cellular response to topologically incorrect protein 3/244 116/18722 0.192912379480832 0.392037672897964 TBL2/HSPA5/DNAJB14 3 GO:0007588 excretion 2/244 62/18722 0.193513422227784 0.392037672897964 ATP6V1B1/MLLT6 2 GO:0009311 oligosaccharide metabolic process 2/244 62/18722 0.193513422227784 0.392037672897964 MANBA/FUT8 2 GO:0010573 vascular endothelial growth factor production 2/244 62/18722 0.193513422227784 0.392037672897964 IL6ST/ISL1 2 GO:0032731 positive regulation of interleukin-1 beta production 2/244 62/18722 0.193513422227784 0.392037672897964 ISL1/APP 2 GO:0046173 polyol biosynthetic process 2/244 62/18722 0.193513422227784 0.392037672897964 P2RY6/ASAH1 2 GO:0046847 filopodium assembly 2/244 62/18722 0.193513422227784 0.392037672897964 ITGB4/PPP1R9A 2 GO:0048488 synaptic vesicle endocytosis 2/244 62/18722 0.193513422227784 0.392037672897964 NLGN4X/CALM1 2 GO:0048663 neuron fate commitment 2/244 62/18722 0.193513422227784 0.392037672897964 ISL1/GLI3 2 GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 2/244 62/18722 0.193513422227784 0.392037672897964 LRP1/BMP7 2 GO:0140238 presynaptic endocytosis 2/244 62/18722 0.193513422227784 0.392037672897964 NLGN4X/CALM1 2 GO:0031647 regulation of protein stability 6/244 298/18722 0.194479205944774 0.393480009518846 GAPDH/AAK1/HTT/PLPP3/TBL1X/GNAQ 6 GO:0090068 positive regulation of cell cycle process 5/244 236/18722 0.195538977322533 0.393480009518846 SVIL/LRP5/ADAMTS1/APP/PBX1 5 GO:0030301 cholesterol transport 3/244 117/18722 0.196227028041361 0.393480009518846 LRP1/SREBF2/TSKU 3 GO:1903828 negative regulation of cellular protein localization 3/244 117/18722 0.196227028041361 0.393480009518846 LATS2/LMAN1/SVIP 3 GO:0010634 positive regulation of epithelial cell migration 4/244 176/18722 0.197746677239108 0.393480009518846 NRP2/MET/LGMN/PLPP3 4 GO:0030239 myofibril assembly 2/244 63/18722 0.198249790876087 0.393480009518846 ITGB1/KRT19 2 GO:0050854 regulation of antigen receptor-mediated signaling pathway 2/244 63/18722 0.198249790876087 0.393480009518846 SLC39A10/KCNN4 2 GO:0099601 regulation of neurotransmitter receptor activity 2/244 63/18722 0.198249790876087 0.393480009518846 APP/AKAP9 2 GO:2000242 negative regulation of reproductive process 2/244 63/18722 0.198249790876087 0.393480009518846 BMP7/GJA1 2 GO:0032259 methylation 7/244 364/18722 0.198540208509515 0.393480009518846 MPHOSPH8/METTL7A/JARID2/MTR/TARBP1/MLLT6/DNMT3A 7 GO:0007613 memory 3/244 118/18722 0.199555639621404 0.393480009518846 SLC6A4/RCAN1/LGMN 3 GO:0045446 endothelial cell differentiation 3/244 118/18722 0.199555639621404 0.393480009518846 NR2F2/MET/VCL 3 GO:0000097 sulfur amino acid biosynthetic process 1/244 17/18722 0.199973102829115 0.393480009518846 MTR 1 GO:0001829 trophectodermal cell differentiation 1/244 17/18722 0.199973102829115 0.393480009518846 HOPX 1 GO:0003184 pulmonary valve morphogenesis 1/244 17/18722 0.199973102829115 0.393480009518846 GJA5 1 GO:0007158 neuron cell-cell adhesion 1/244 17/18722 0.199973102829115 0.393480009518846 NLGN4X 1 GO:0010224 response to UV-B 1/244 17/18722 0.199973102829115 0.393480009518846 HYAL2 1 GO:0010470 regulation of gastrulation 1/244 17/18722 0.199973102829115 0.393480009518846 DAG1 1 GO:0010612 regulation of cardiac muscle adaptation 1/244 17/18722 0.199973102829115 0.393480009518846 ATP2B4 1 GO:0015867 ATP transport 1/244 17/18722 0.199973102829115 0.393480009518846 GJA1 1 GO:0021513 spinal cord dorsal/ventral patterning 1/244 17/18722 0.199973102829115 0.393480009518846 GLI3 1 GO:0030322 stabilization of membrane potential 1/244 17/18722 0.199973102829115 0.393480009518846 KCNN4 1 GO:0031445 regulation of heterochromatin assembly 1/244 17/18722 0.199973102829115 0.393480009518846 MPHOSPH8 1 GO:0032604 granulocyte macrophage colony-stimulating factor production 1/244 17/18722 0.199973102829115 0.393480009518846 ISL1 1 GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 1/244 17/18722 0.199973102829115 0.393480009518846 ISL1 1 GO:0035269 protein O-linked mannosylation 1/244 17/18722 0.199973102829115 0.393480009518846 TMTC3 1 GO:0035729 cellular response to hepatocyte growth factor stimulus 1/244 17/18722 0.199973102829115 0.393480009518846 LGMN 1 GO:0036035 osteoclast development 1/244 17/18722 0.199973102829115 0.393480009518846 FBN1 1 GO:0036065 fucosylation 1/244 17/18722 0.199973102829115 0.393480009518846 FUT8 1 GO:0042339 keratan sulfate metabolic process 1/244 17/18722 0.199973102829115 0.393480009518846 GNS 1 GO:0044539 long-chain fatty acid import into cell 1/244 17/18722 0.199973102829115 0.393480009518846 SLC27A2 1 GO:0048339 paraxial mesoderm development 1/244 17/18722 0.199973102829115 0.393480009518846 FOXC1 1 GO:0051580 regulation of neurotransmitter uptake 1/244 17/18722 0.199973102829115 0.393480009518846 ITGB1 1 GO:0060033 anatomical structure regression 1/244 17/18722 0.199973102829115 0.393480009518846 LRP5 1 GO:0061298 retina vasculature development in camera-type eye 1/244 17/18722 0.199973102829115 0.393480009518846 LRP5 1 GO:0070593 dendrite self-avoidance 1/244 17/18722 0.199973102829115 0.393480009518846 PALLD 1 GO:0072673 lamellipodium morphogenesis 1/244 17/18722 0.199973102829115 0.393480009518846 KANK1 1 GO:0090136 epithelial cell-cell adhesion 1/244 17/18722 0.199973102829115 0.393480009518846 VCL 1 GO:0097067 cellular response to thyroid hormone stimulus 1/244 17/18722 0.199973102829115 0.393480009518846 CTSL 1 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity 1/244 17/18722 0.199973102829115 0.393480009518846 AKAP9 1 GO:0120261 regulation of heterochromatin organization 1/244 17/18722 0.199973102829115 0.393480009518846 MPHOSPH8 1 GO:0140354 lipid import into cell 1/244 17/18722 0.199973102829115 0.393480009518846 SLC27A2 1 GO:1901550 regulation of endothelial cell development 1/244 17/18722 0.199973102829115 0.393480009518846 VCL 1 GO:1902358 sulfate transmembrane transport 1/244 17/18722 0.199973102829115 0.393480009518846 SLC26A2 1 GO:1903140 regulation of establishment of endothelial barrier 1/244 17/18722 0.199973102829115 0.393480009518846 VCL 1 GO:1903242 regulation of cardiac muscle hypertrophy in response to stress 1/244 17/18722 0.199973102829115 0.393480009518846 ATP2B4 1 GO:1903358 regulation of Golgi organization 1/244 17/18722 0.199973102829115 0.393480009518846 AKAP9 1 GO:2000811 negative regulation of anoikis 1/244 17/18722 0.199973102829115 0.393480009518846 ITGB1 1 GO:0030324 lung development 4/244 177/18722 0.200416121601348 0.394115724465606 DAG1/LAMA5/GLI3/HOPX 4 GO:0051056 regulation of small GTPase mediated signal transduction 6/244 302/18722 0.202496767604655 0.396350823975959 KANK1/SYDE2/MET/ITGAV/ITGB1/AMOT 6 GO:0001885 endothelial cell development 2/244 64/18722 0.203000132912824 0.396350823975959 MET/VCL 2 GO:0032507 maintenance of protein location in cell 2/244 64/18722 0.203000132912824 0.396350823975959 HSPA5/GJA1 2 GO:0046530 photoreceptor cell differentiation 2/244 64/18722 0.203000132912824 0.396350823975959 NAGLU/TUG1 2 GO:0046888 negative regulation of hormone secretion 2/244 64/18722 0.203000132912824 0.396350823975959 GJA1/RAB11FIP1 2 GO:0048857 neural nucleus development 2/244 64/18722 0.203000132912824 0.396350823975959 CALM1/HSPA5 2 GO:0050771 negative regulation of axonogenesis 2/244 64/18722 0.203000132912824 0.396350823975959 SEMA6A/SEMA6D 2 GO:0055002 striated muscle cell development 2/244 64/18722 0.203000132912824 0.396350823975959 ITGB1/KRT19 2 GO:0098930 axonal transport 2/244 64/18722 0.203000132912824 0.396350823975959 ARMCX3/DST 2 GO:1900076 regulation of cellular response to insulin stimulus 2/244 64/18722 0.203000132912824 0.396350823975959 KANK1/ATP2B1 2 GO:1903018 regulation of glycoprotein metabolic process 2/244 64/18722 0.203000132912824 0.396350823975959 ITM2B/CST3 2 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process 2/244 64/18722 0.203000132912824 0.396350823975959 USP25/SVIP 2 GO:0007416 synapse assembly 4/244 179/18722 0.205787440158606 0.400350040361366 NLGN4X/PPP1R9A/APP/CDH1 4 GO:0044843 cell cycle G1/S phase transition 5/244 241/18722 0.206948832006566 0.400350040361366 ADAMTS1/LATS2/ITGB1/ATP2B4/CTDSPL 5 GO:0008380 RNA splicing 8/244 434/18722 0.206996489262493 0.400350040361366 AHNAK/SUGP2/SON/SRSF2/SRRM2/SF1/DDX5/RBM25 8 GO:0006487 protein N-linked glycosylation 2/244 65/18722 0.207763285816048 0.400350040361366 FUT8/RPN2 2 GO:0048524 positive regulation of viral process 2/244 65/18722 0.207763285816048 0.400350040361366 HACD3/P4HB 2 GO:0071677 positive regulation of mononuclear cell migration 2/244 65/18722 0.207763285816048 0.400350040361366 APP/LGMN 2 GO:0043409 negative regulation of MAPK cascade 4/244 180/18722 0.208488877967219 0.400350040361366 SEMA6A/BMP7/DAG1/HYAL2 4 GO:0048706 embryonic skeletal system development 3/244 121/18722 0.209620904381604 0.400350040361366 BMP7/PBX1/GLI3 3 GO:0001522 pseudouridine synthesis 1/244 18/18722 0.210409166069409 0.400350040361366 NAF1 1 GO:0001946 lymphangiogenesis 1/244 18/18722 0.210409166069409 0.400350040361366 FOXC1 1 GO:0002076 osteoblast development 1/244 18/18722 0.210409166069409 0.400350040361366 LRP5 1 GO:0002544 chronic inflammatory response 1/244 18/18722 0.210409166069409 0.400350040361366 GJA1 1 GO:0003417 growth plate cartilage development 1/244 18/18722 0.210409166069409 0.400350040361366 TSKU 1 GO:0006085 acetyl-CoA biosynthetic process 1/244 18/18722 0.210409166069409 0.400350040361366 ACSS1 1 GO:0006991 response to sterol depletion 1/244 18/18722 0.210409166069409 0.400350040361366 SREBF2 1 GO:0008272 sulfate transport 1/244 18/18722 0.210409166069409 0.400350040361366 SLC26A2 1 GO:0019896 axonal transport of mitochondrion 1/244 18/18722 0.210409166069409 0.400350040361366 ARMCX3 1 GO:0021511 spinal cord patterning 1/244 18/18722 0.210409166069409 0.400350040361366 GLI3 1 GO:0030728 ovulation 1/244 18/18722 0.210409166069409 0.400350040361366 ADAMTS1 1 GO:0031643 positive regulation of myelination 1/244 18/18722 0.210409166069409 0.400350040361366 DAG1 1 GO:0031649 heat generation 1/244 18/18722 0.210409166069409 0.400350040361366 ADRB1 1 GO:0032769 negative regulation of monooxygenase activity 1/244 18/18722 0.210409166069409 0.400350040361366 ATP2B4 1 GO:0033189 response to vitamin A 1/244 18/18722 0.210409166069409 0.400350040361366 DNMT3A 1 GO:0036499 PERK-mediated unfolded protein response 1/244 18/18722 0.210409166069409 0.400350040361366 HSPA5 1 GO:0042136 neurotransmitter biosynthetic process 1/244 18/18722 0.210409166069409 0.400350040361366 SLC6A4 1 GO:0045187 regulation of circadian sleep/wake cycle, sleep 1/244 18/18722 0.210409166069409 0.400350040361366 ADRB1 1 GO:0048486 parasympathetic nervous system development 1/244 18/18722 0.210409166069409 0.400350040361366 NRP2 1 GO:0051895 negative regulation of focal adhesion assembly 1/244 18/18722 0.210409166069409 0.400350040361366 LRP1 1 GO:0055070 copper ion homeostasis 1/244 18/18722 0.210409166069409 0.400350040361366 APP 1 GO:0060008 Sertoli cell differentiation 1/244 18/18722 0.210409166069409 0.400350040361366 CTSV 1 GO:0061484 hematopoietic stem cell homeostasis 1/244 18/18722 0.210409166069409 0.400350040361366 OCIAD2 1 GO:0072234 metanephric nephron tubule development 1/244 18/18722 0.210409166069409 0.400350040361366 LGR4 1 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis 1/244 18/18722 0.210409166069409 0.400350040361366 LGR4 1 GO:0097094 craniofacial suture morphogenesis 1/244 18/18722 0.210409166069409 0.400350040361366 GLI3 1 GO:0150118 negative regulation of cell-substrate junction organization 1/244 18/18722 0.210409166069409 0.400350040361366 LRP1 1 GO:1900006 positive regulation of dendrite development 1/244 18/18722 0.210409166069409 0.400350040361366 BMP7 1 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1/244 18/18722 0.210409166069409 0.400350040361366 TNRC6B 1 GO:1900242 regulation of synaptic vesicle endocytosis 1/244 18/18722 0.210409166069409 0.400350040361366 CALM1 1 GO:1900424 regulation of defense response to bacterium 1/244 18/18722 0.210409166069409 0.400350040361366 MAPKBP1 1 GO:1902074 response to salt 1/244 18/18722 0.210409166069409 0.400350040361366 HSPA5 1 GO:1902170 cellular response to reactive nitrogen species 1/244 18/18722 0.210409166069409 0.400350040361366 MTR 1 GO:1902683 regulation of receptor localization to synapse 1/244 18/18722 0.210409166069409 0.400350040361366 DAG1 1 GO:1904872 regulation of telomerase RNA localization to Cajal body 1/244 18/18722 0.210409166069409 0.400350040361366 NAF1 1 GO:2000136 regulation of cell proliferation involved in heart morphogenesis 1/244 18/18722 0.210409166069409 0.400350040361366 ISL1 1 GO:0030323 respiratory tube development 4/244 181/18722 0.211200543911501 0.401158952192597 DAG1/LAMA5/GLI3/HOPX 4 GO:0045766 positive regulation of angiogenesis 4/244 181/18722 0.211200543911501 0.401158952192597 ISL1/ITGB1/ITGB8/STIM1 4 GO:1904018 positive regulation of vasculature development 4/244 181/18722 0.211200543911501 0.401158952192597 ISL1/ITGB1/ITGB8/STIM1 4 GO:0007159 leukocyte cell-cell adhesion 7/244 371/18722 0.211370812377703 0.401250427194184 IL6ST/BMP7/ITGB1/OLR1/MIA3/DPP4/GLI3 7 GO:0050918 positive chemotaxis 2/244 66/18722 0.212538114756206 0.40300071845868 LRP1/MET 2 GO:1905953 negative regulation of lipid localization 2/244 66/18722 0.212538114756206 0.40300071845868 ITGAV/SREBF2 2 GO:0030168 platelet activation 3/244 123/18722 0.216392971398642 0.407903202726115 IL6ST/VCL/SERPINE2 3 GO:0009583 detection of light stimulus 2/244 67/18722 0.217323512076819 0.407903202726115 CDS1/GNAQ 2 GO:0061077 chaperone-mediated protein folding 2/244 67/18722 0.217323512076819 0.407903202726115 HSPA5/DNAJB14 2 GO:1902117 positive regulation of organelle assembly 2/244 67/18722 0.217323512076819 0.407903202726115 DZIP1/HTT 2 GO:0007015 actin filament organization 8/244 441/18722 0.218959821644959 0.407903202726115 SVIL/PPP1R9A/POF1B/KANK1/TACSTD2/IQGAP2/MET/SPTBN1 8 GO:0055001 muscle cell development 4/244 184/18722 0.219394730668155 0.407903202726115 ISL1/ITGB1/RCAN1/KRT19 4 GO:0009132 nucleoside diphosphate metabolic process 3/244 124/18722 0.219796296482276 0.407903202726115 APP/LDHA/GAPDH 3 GO:0097237 cellular response to toxic substance 3/244 124/18722 0.219796296482276 0.407903202726115 PPP1R9A/BMP7/SOD3 3 GO:0002902 regulation of B cell apoptotic process 1/244 19/18722 0.220709645297332 0.407903202726115 SLC39A10 1 GO:0003085 negative regulation of systemic arterial blood pressure 1/244 19/18722 0.220709645297332 0.407903202726115 ADRB1 1 GO:0006007 glucose catabolic process 1/244 19/18722 0.220709645297332 0.407903202726115 LRP5 1 GO:0006044 N-acetylglucosamine metabolic process 1/244 19/18722 0.220709645297332 0.407903202726115 EXTL2 1 GO:0007213 G protein-coupled acetylcholine receptor signaling pathway 1/244 19/18722 0.220709645297332 0.407903202726115 GNAQ 1 GO:0007530 sex determination 1/244 19/18722 0.220709645297332 0.407903202726115 SF1 1 GO:0007603 phototransduction, visible light 1/244 19/18722 0.220709645297332 0.407903202726115 GNAQ 1 GO:0010002 cardioblast differentiation 1/244 19/18722 0.220709645297332 0.407903202726115 ISL1 1 GO:0010544 negative regulation of platelet activation 1/244 19/18722 0.220709645297332 0.407903202726115 SERPINE2 1 GO:0010885 regulation of cholesterol storage 1/244 19/18722 0.220709645297332 0.407903202726115 SREBF2 1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling 1/244 19/18722 0.220709645297332 0.407903202726115 SERPINE2 1 GO:0015802 basic amino acid transport 1/244 19/18722 0.220709645297332 0.407903202726115 SLC38A9 1 GO:0030011 maintenance of cell polarity 1/244 19/18722 0.220709645297332 0.407903202726115 DST 1 GO:0031290 retinal ganglion cell axon guidance 1/244 19/18722 0.220709645297332 0.407903202726115 ISL1 1 GO:0035728 response to hepatocyte growth factor 1/244 19/18722 0.220709645297332 0.407903202726115 LGMN 1 GO:0036498 IRE1-mediated unfolded protein response 1/244 19/18722 0.220709645297332 0.407903202726115 HSPA5 1 GO:0042474 middle ear morphogenesis 1/244 19/18722 0.220709645297332 0.407903202726115 NAGLU 1 GO:0045019 negative regulation of nitric oxide biosynthetic process 1/244 19/18722 0.220709645297332 0.407903202726115 ATP2B4 1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate 1/244 19/18722 0.220709645297332 0.407903202726115 MPHOSPH8 1 GO:0045618 positive regulation of keratinocyte differentiation 1/244 19/18722 0.220709645297332 0.407903202726115 FOXC1 1 GO:0045821 positive regulation of glycolytic process 1/244 19/18722 0.220709645297332 0.407903202726115 APP 1 GO:0046794 transport of virus 1/244 19/18722 0.220709645297332 0.407903202726115 CTSL 1 GO:0051957 positive regulation of amino acid transport 1/244 19/18722 0.220709645297332 0.407903202726115 ITGB1 1 GO:0060039 pericardium development 1/244 19/18722 0.220709645297332 0.407903202726115 BMP7 1 GO:0060216 definitive hemopoiesis 1/244 19/18722 0.220709645297332 0.407903202726115 TGFBR3 1 GO:0061323 cell proliferation involved in heart morphogenesis 1/244 19/18722 0.220709645297332 0.407903202726115 ISL1 1 GO:0072074 kidney mesenchyme development 1/244 19/18722 0.220709645297332 0.407903202726115 BMP7 1 GO:0090670 RNA localization to Cajal body 1/244 19/18722 0.220709645297332 0.407903202726115 NAF1 1 GO:0090671 telomerase RNA localization to Cajal body 1/244 19/18722 0.220709645297332 0.407903202726115 NAF1 1 GO:0090672 telomerase RNA localization 1/244 19/18722 0.220709645297332 0.407903202726115 NAF1 1 GO:0090685 RNA localization to nucleus 1/244 19/18722 0.220709645297332 0.407903202726115 NAF1 1 GO:0097501 stress response to metal ion 1/244 19/18722 0.220709645297332 0.407903202726115 HSPA5 1 GO:0098780 response to mitochondrial depolarisation 1/244 19/18722 0.220709645297332 0.407903202726115 HUWE1 1 GO:1900221 regulation of amyloid-beta clearance 1/244 19/18722 0.220709645297332 0.407903202726115 LRP1 1 GO:1903975 regulation of glial cell migration 1/244 19/18722 0.220709645297332 0.407903202726115 LRP1 1 GO:1904406 negative regulation of nitric oxide metabolic process 1/244 19/18722 0.220709645297332 0.407903202726115 ATP2B4 1 GO:2000369 regulation of clathrin-dependent endocytosis 1/244 19/18722 0.220709645297332 0.407903202726115 AAK1 1 GO:0009988 cell-cell recognition 2/244 68/18722 0.222118396783915 0.408488470960838 FOLR1/SPESP1 2 GO:0032922 circadian regulation of gene expression 2/244 68/18722 0.222118396783915 0.408488470960838 HUWE1/LGR4 2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 2/244 68/18722 0.222118396783915 0.408488470960838 IL6ST/ISL1 2 GO:0042698 ovulation cycle 2/244 68/18722 0.222118396783915 0.408488470960838 ADAMTS1/HSPA5 2 GO:0061912 selective autophagy 2/244 68/18722 0.222118396783915 0.408488470960838 HUWE1/HTT 2 GO:1901016 regulation of potassium ion transmembrane transporter activity 2/244 68/18722 0.222118396783915 0.408488470960838 AKAP9/ITGB1 2 GO:1901607 alpha-amino acid biosynthetic process 2/244 68/18722 0.222118396783915 0.408488470960838 ATP2B4/MTR 2 GO:1902305 regulation of sodium ion transmembrane transport 2/244 68/18722 0.222118396783915 0.408488470960838 UTRN/ATP2B4 2 GO:0002040 sprouting angiogenesis 4/244 185/18722 0.22214513012995 0.408488470960838 EPHB4/SEMA6A/ITGB1/MIA3 4 GO:2000027 regulation of animal organ morphogenesis 3/244 125/18722 0.223210589214914 0.410114293174395 TACSTD2/BMP7/LGR4 3 GO:0021537 telencephalon development 5/244 248/18722 0.223278901548689 0.410114293174395 LRP1/LAMB1/ATP2B4/GLI3/TSKU 5 GO:0031060 regulation of histone methylation 2/244 69/18722 0.22692171404406 0.414794699218566 JARID2/MLLT6 2 GO:0050810 regulation of steroid biosynthetic process 2/244 69/18722 0.22692171404406 0.414794699218566 ASAH1/SF1 2 GO:0060193 positive regulation of lipase activity 2/244 69/18722 0.22692171404406 0.414794699218566 P2RY6/GNAQ 2 GO:0046394 carboxylic acid biosynthetic process 6/244 314/18722 0.227242348213687 0.414794699218566 HACD3/SLC27A2/ACSS1/ATP2B4/MTR/SLC1A3 6 GO:0035270 endocrine system development 3/244 127/18722 0.230070415828744 0.414794699218566 ISL1/PBX1/CDH1 3 GO:0048565 digestive tract development 3/244 127/18722 0.230070415828744 0.414794699218566 IL6ST/LGR4/GLI3 3 GO:0050678 regulation of epithelial cell proliferation 7/244 381/18722 0.230215911360228 0.414794699218566 LAMC1/NR2F2/NRP2/LAMB1/ISL1/GJA1/TGFBR3 7 GO:0006575 cellular modified amino acid metabolic process 4/244 188/18722 0.230450299007852 0.414794699218566 FOLR1/SLC46A1/CPQ/SLC19A1 4 GO:0002115 store-operated calcium entry 1/244 20/18722 0.230876294848069 0.414794699218566 STIM1 1 GO:0003215 cardiac right ventricle morphogenesis 1/244 20/18722 0.230876294848069 0.414794699218566 ISL1 1 GO:0006525 arginine metabolic process 1/244 20/18722 0.230876294848069 0.414794699218566 ATP2B4 1 GO:0006590 thyroid hormone generation 1/244 20/18722 0.230876294848069 0.414794699218566 CPQ 1 GO:0006837 serotonin transport 1/244 20/18722 0.230876294848069 0.414794699218566 SLC6A4 1 GO:0006883 cellular sodium ion homeostasis 1/244 20/18722 0.230876294848069 0.414794699218566 SLC1A3 1 GO:0007097 nuclear migration 1/244 20/18722 0.230876294848069 0.414794699218566 SYNE2 1 GO:0007194 negative regulation of adenylate cyclase activity 1/244 20/18722 0.230876294848069 0.414794699218566 AKAP9 1 GO:0010523 negative regulation of calcium ion transport into cytosol 1/244 20/18722 0.230876294848069 0.414794699218566 CALM1 1 GO:0010801 negative regulation of peptidyl-threonine phosphorylation 1/244 20/18722 0.230876294848069 0.414794699218566 CALM1 1 GO:0014047 glutamate secretion 1/244 20/18722 0.230876294848069 0.414794699218566 GJA1 1 GO:0032332 positive regulation of chondrocyte differentiation 1/244 20/18722 0.230876294848069 0.414794699218566 GLI3 1 GO:0034104 negative regulation of tissue remodeling 1/244 20/18722 0.230876294848069 0.414794699218566 CST3 1 GO:0039535 regulation of RIG-I signaling pathway 1/244 20/18722 0.230876294848069 0.414794699218566 PUM1 1 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate 1/244 20/18722 0.230876294848069 0.414794699218566 MPHOSPH8 1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process 1/244 20/18722 0.230876294848069 0.414794699218566 ITM2B 1 GO:0043011 myeloid dendritic cell differentiation 1/244 20/18722 0.230876294848069 0.414794699218566 ITGB8 1 GO:0043046 DNA methylation involved in gamete generation 1/244 20/18722 0.230876294848069 0.414794699218566 DNMT3A 1 GO:0043586 tongue development 1/244 20/18722 0.230876294848069 0.414794699218566 GLI3 1 GO:0043984 histone H4-K16 acetylation 1/244 20/18722 0.230876294848069 0.414794699218566 PHF20 1 GO:0046485 ether lipid metabolic process 1/244 20/18722 0.230876294848069 0.414794699218566 NCEH1 1 GO:0048670 regulation of collateral sprouting 1/244 20/18722 0.230876294848069 0.414794699218566 LRP1 1 GO:0070166 enamel mineralization 1/244 20/18722 0.230876294848069 0.414794699218566 STIM1 1 GO:0071379 cellular response to prostaglandin stimulus 1/244 20/18722 0.230876294848069 0.414794699218566 P2RY6 1 GO:0071397 cellular response to cholesterol 1/244 20/18722 0.230876294848069 0.414794699218566 DAG1 1 GO:0071731 response to nitric oxide 1/244 20/18722 0.230876294848069 0.414794699218566 MTR 1 GO:0072567 chemokine (C-X-C motif) ligand 2 production 1/244 20/18722 0.230876294848069 0.414794699218566 LRP1 1 GO:0090370 negative regulation of cholesterol efflux 1/244 20/18722 0.230876294848069 0.414794699218566 SREBF2 1 GO:1901386 negative regulation of voltage-gated calcium channel activity 1/244 20/18722 0.230876294848069 0.414794699218566 CALM1 1 GO:1901679 nucleotide transmembrane transport 1/244 20/18722 0.230876294848069 0.414794699218566 SLC19A1 1 GO:1903206 negative regulation of hydrogen peroxide-induced cell death 1/244 20/18722 0.230876294848069 0.414794699218566 MET 1 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production 1/244 20/18722 0.230876294848069 0.414794699218566 LRP1 1 GO:0010876 lipid localization 8/244 448/18722 0.231177633174342 0.415109127109774 LRP1/KCNN4/CDS1/ITGAV/SLC27A2/SREBF2/PLEKHA8/TSKU 8 GO:0016053 organic acid biosynthetic process 6/244 316/18722 0.231460226820482 0.415389571453908 HACD3/SLC27A2/ACSS1/ATP2B4/MTR/SLC1A3 6 GO:0010506 regulation of autophagy 6/244 317/18722 0.23357852176608 0.41896234853894 MET/ATP6V1B1/GAPDH/HTT/SREBF2/SVIP 6 GO:0022412 cellular process involved in reproduction in multicellular organism 7/244 384/18722 0.23597937119083 0.42166331944619 LGR5/ITGB1/DZIP1/FOLR1/SPESP1/FOXC1/DNMT3A 7 GO:0008344 adult locomotory behavior 2/244 71/18722 0.236549554739783 0.42166331944619 APP/PUM1 2 GO:0032722 positive regulation of chemokine production 2/244 71/18722 0.236549554739783 0.42166331944619 LRP1/APP 2 GO:0050795 regulation of behavior 2/244 71/18722 0.236549554739783 0.42166331944619 ADRB1/GJA1 2 GO:0061515 myeloid cell development 2/244 71/18722 0.236549554739783 0.42166331944619 FBN1/APP 2 GO:0071230 cellular response to amino acid stimulus 2/244 71/18722 0.236549554739783 0.42166331944619 SLC38A9/DNMT3A 2 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 6/244 320/18722 0.239969736406692 0.42166331944619 SON/SRSF2/SRRM2/SF1/DDX5/RBM25 6 GO:0000398 mRNA splicing, via spliceosome 6/244 320/18722 0.239969736406692 0.42166331944619 SON/SRSF2/SRRM2/SF1/DDX5/RBM25 6 GO:0043547 positive regulation of GTPase activity 5/244 255/18722 0.239983602887152 0.42166331944619 RGL3/ADRB1/SYDE2/ITGB1/DOCK9 5 GO:1903362 regulation of cellular protein catabolic process 5/244 255/18722 0.239983602887152 0.42166331944619 LRP2/LRP1/TMTC3/USP25/SVIP 5 GO:0015918 sterol transport 3/244 130/18722 0.24043211047997 0.42166331944619 LRP1/SREBF2/TSKU 3 GO:0002689 negative regulation of leukocyte chemotaxis 1/244 21/18722 0.240910846449881 0.42166331944619 DPP4 1 GO:0003177 pulmonary valve development 1/244 21/18722 0.240910846449881 0.42166331944619 GJA5 1 GO:0006067 ethanol metabolic process 1/244 21/18722 0.240910846449881 0.42166331944619 ACSS1 1 GO:0006925 inflammatory cell apoptotic process 1/244 21/18722 0.240910846449881 0.42166331944619 CTSL 1 GO:0007350 blastoderm segmentation 1/244 21/18722 0.240910846449881 0.42166331944619 NRP2 1 GO:0007617 mating behavior 1/244 21/18722 0.240910846449881 0.42166331944619 APP 1 GO:0008090 retrograde axonal transport 1/244 21/18722 0.240910846449881 0.42166331944619 DST 1 GO:0009067 aspartate family amino acid biosynthetic process 1/244 21/18722 0.240910846449881 0.42166331944619 MTR 1 GO:0010766 negative regulation of sodium ion transport 1/244 21/18722 0.240910846449881 0.42166331944619 SERPINE2 1 GO:0010878 cholesterol storage 1/244 21/18722 0.240910846449881 0.42166331944619 SREBF2 1 GO:0032288 myelin assembly 1/244 21/18722 0.240910846449881 0.42166331944619 ITGB4 1 GO:0034035 purine ribonucleoside bisphosphate metabolic process 1/244 21/18722 0.240910846449881 0.42166331944619 SLC26A2 1 GO:0034312 diol biosynthetic process 1/244 21/18722 0.240910846449881 0.42166331944619 ASAH1 1 GO:0035330 regulation of hippo signaling 1/244 21/18722 0.240910846449881 0.42166331944619 WWC1 1 GO:0043373 CD4-positive, alpha-beta T cell lineage commitment 1/244 21/18722 0.240910846449881 0.42166331944619 CTSL 1 GO:0044766 multi-organism transport 1/244 21/18722 0.240910846449881 0.42166331944619 CTSL 1 GO:0045655 regulation of monocyte differentiation 1/244 21/18722 0.240910846449881 0.42166331944619 JUN 1 GO:0046514 ceramide catabolic process 1/244 21/18722 0.240910846449881 0.42166331944619 ASAH1 1 GO:0048485 sympathetic nervous system development 1/244 21/18722 0.240910846449881 0.42166331944619 NRP2 1 GO:0048714 positive regulation of oligodendrocyte differentiation 1/244 21/18722 0.240910846449881 0.42166331944619 DAG1 1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process 1/244 21/18722 0.240910846449881 0.42166331944619 SLC26A2 1 GO:0050802 circadian sleep/wake cycle, sleep 1/244 21/18722 0.240910846449881 0.42166331944619 ADRB1 1 GO:0071498 cellular response to fluid shear stress 1/244 21/18722 0.240910846449881 0.42166331944619 SREBF2 1 GO:0072111 cell proliferation involved in kidney development 1/244 21/18722 0.240910846449881 0.42166331944619 BMP7 1 GO:0072170 metanephric tubule development 1/244 21/18722 0.240910846449881 0.42166331944619 LGR4 1 GO:0072243 metanephric nephron epithelium development 1/244 21/18722 0.240910846449881 0.42166331944619 LGR4 1 GO:0090026 positive regulation of monocyte chemotaxis 1/244 21/18722 0.240910846449881 0.42166331944619 LGMN 1 GO:0099515 actin filament-based transport 1/244 21/18722 0.240910846449881 0.42166331944619 SYNE2 1 GO:0150105 protein localization to cell-cell junction 1/244 21/18722 0.240910846449881 0.42166331944619 VCL 1 GO:1902473 regulation of protein localization to synapse 1/244 21/18722 0.240910846449881 0.42166331944619 DAG1 1 GO:1902579 multi-organism localization 1/244 21/18722 0.240910846449881 0.42166331944619 CTSL 1 GO:2000291 regulation of myoblast proliferation 1/244 21/18722 0.240910846449881 0.42166331944619 MALAT1 1 GO:2001014 regulation of skeletal muscle cell differentiation 1/244 21/18722 0.240910846449881 0.42166331944619 DDX5 1 GO:0030032 lamellipodium assembly 2/244 72/18722 0.241372094911224 0.42166331944619 ITGB1/VCL 2 GO:0043903 regulation of biological process involved in symbiotic interaction 2/244 72/18722 0.241372094911224 0.42166331944619 ITGAV/P4HB 2 GO:0050709 negative regulation of protein secretion 2/244 72/18722 0.241372094911224 0.42166331944619 ERP29/RAB11FIP1 2 GO:0070227 lymphocyte apoptotic process 2/244 72/18722 0.241372094911224 0.42166331944619 SLC39A10/GLI3 2 GO:1901880 negative regulation of protein depolymerization 2/244 72/18722 0.241372094911224 0.42166331944619 SVIL/SPTBN1 2 GO:0019079 viral genome replication 3/244 131/18722 0.24390358008736 0.425859279578674 MPHOSPH8/HACD3/DDX5 3 GO:0032732 positive regulation of interleukin-1 production 2/244 73/18722 0.246199100161584 0.429410957075885 ISL1/APP 2 GO:0061035 regulation of cartilage development 2/244 73/18722 0.246199100161584 0.429410957075885 GLI3/EFEMP1 2 GO:0045165 cell fate commitment 5/244 258/18722 0.247246117580729 0.431008351390067 NR2F2/ISL1/CTSL/ITGB1/GLI3 5 GO:0035264 multicellular organism growth 3/244 132/18722 0.247383171660894 0.431018611918186 ADRB1/APP/LGMN 3 GO:0000375 RNA splicing, via transesterification reactions 6/244 324/18722 0.248572707772897 0.431424369500314 SON/SRSF2/SRRM2/SF1/DDX5/RBM25 6 GO:0002053 positive regulation of mesenchymal cell proliferation 1/244 22/18722 0.250815009514221 0.431424369500314 LRP5 1 GO:0006662 glycerol ether metabolic process 1/244 22/18722 0.250815009514221 0.431424369500314 NCEH1 1 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 1/244 22/18722 0.250815009514221 0.431424369500314 CALM1 1 GO:0021854 hypothalamus development 1/244 22/18722 0.250815009514221 0.431424369500314 NRP2 1 GO:0021904 dorsal/ventral neural tube patterning 1/244 22/18722 0.250815009514221 0.431424369500314 GLI3 1 GO:0031281 positive regulation of cyclase activity 1/244 22/18722 0.250815009514221 0.431424369500314 STIM1 1 GO:0034629 cellular protein-containing complex localization 1/244 22/18722 0.250815009514221 0.431424369500314 AKAP9 1 GO:0035268 protein mannosylation 1/244 22/18722 0.250815009514221 0.431424369500314 TMTC3 1 GO:0042749 regulation of circadian sleep/wake cycle 1/244 22/18722 0.250815009514221 0.431424369500314 ADRB1 1 GO:0045061 thymic T cell selection 1/244 22/18722 0.250815009514221 0.431424369500314 GLI3 1 GO:0048169 regulation of long-term neuronal synaptic plasticity 1/244 22/18722 0.250815009514221 0.431424369500314 APP 1 GO:0051220 cytoplasmic sequestering of protein 1/244 22/18722 0.250815009514221 0.431424369500314 DZIP1 1 GO:0060444 branching involved in mammary gland duct morphogenesis 1/244 22/18722 0.250815009514221 0.431424369500314 LRP5 1 GO:0060965 negative regulation of gene silencing by miRNA 1/244 22/18722 0.250815009514221 0.431424369500314 KCNQ1OT1 1 GO:0099563 modification of synaptic structure 1/244 22/18722 0.250815009514221 0.431424369500314 MYH10 1 GO:0140467 integrated stress response signaling 1/244 22/18722 0.250815009514221 0.431424369500314 HSPA5 1 GO:1901032 negative regulation of response to reactive oxygen species 1/244 22/18722 0.250815009514221 0.431424369500314 MET 1 GO:2000114 regulation of establishment of cell polarity 1/244 22/18722 0.250815009514221 0.431424369500314 KANK1 1 GO:0046887 positive regulation of hormone secretion 3/244 133/18722 0.25087049214061 0.431424369500314 LRP1/ISL1/GJA1 3 GO:0006801 superoxide metabolic process 2/244 74/18722 0.251029639222337 0.431424369500314 BMP7/SOD3 2 GO:0007040 lysosome organization 2/244 74/18722 0.251029639222337 0.431424369500314 NAGLU/HOOK2 2 GO:0030968 endoplasmic reticulum unfolded protein response 2/244 74/18722 0.251029639222337 0.431424369500314 TBL2/HSPA5 2 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 2/244 74/18722 0.251029639222337 0.431424369500314 ISL1/DDX5 2 GO:0080171 lytic vacuole organization 2/244 74/18722 0.251029639222337 0.431424369500314 NAGLU/HOOK2 2 GO:1903201 regulation of oxidative stress-induced cell death 2/244 74/18722 0.251029639222337 0.431424369500314 MET/P4HB 2 GO:0090150 establishment of protein localization to membrane 5/244 260/18722 0.25211957315344 0.433071049337274 TCAF1/CALM1/HSPA5/MACF1/SPTBN1 5 GO:0022408 negative regulation of cell-cell adhesion 4/244 196/18722 0.252955223395771 0.434279448316878 MIA3/GLI3/CDH1/SERPINE2 4 GO:0010952 positive regulation of peptidase activity 4/244 197/18722 0.255801078950601 0.438355148293381 APP/CLDN4/PCOLCE2/LGMN 4 GO:0036465 synaptic vesicle recycling 2/244 75/18722 0.255862804146898 0.438355148293381 NLGN4X/CALM1 2 GO:0045913 positive regulation of carbohydrate metabolic process 2/244 75/18722 0.255862804146898 0.438355148293381 APP/P2RY6 2 GO:1903363 negative regulation of cellular protein catabolic process 2/244 75/18722 0.255862804146898 0.438355148293381 USP25/SVIP 2 GO:0001101 response to acid chemical 3/244 135/18722 0.257866765209361 0.438634241995392 SLC38A9/ATP2B4/DNMT3A 3 GO:0002687 positive regulation of leukocyte migration 3/244 135/18722 0.257866765209361 0.438634241995392 APP/MIA3/LGMN 3 GO:0009581 detection of external stimulus 3/244 135/18722 0.257866765209361 0.438634241995392 CDS1/GNAQ/SERPINE2 3 GO:0048167 regulation of synaptic plasticity 4/244 198/18722 0.258653503052206 0.438634241995392 PPP1R9A/APP/LGMN/SERPINE2 4 GO:0002052 positive regulation of neuroblast proliferation 1/244 23/18722 0.260590471422164 0.438634241995392 GLI3 1 GO:0002363 alpha-beta T cell lineage commitment 1/244 23/18722 0.260590471422164 0.438634241995392 CTSL 1 GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 1/244 23/18722 0.260590471422164 0.438634241995392 ENPEP 1 GO:0006833 water transport 1/244 23/18722 0.260590471422164 0.438634241995392 HYAL2 1 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 1/244 23/18722 0.260590471422164 0.438634241995392 LRP1 1 GO:0010888 negative regulation of lipid storage 1/244 23/18722 0.260590471422164 0.438634241995392 ITGAV 1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules 1/244 23/18722 0.260590471422164 0.438634241995392 CLDN4 1 GO:0021544 subpallium development 1/244 23/18722 0.260590471422164 0.438634241995392 GLI3 1 GO:0021884 forebrain neuron development 1/244 23/18722 0.260590471422164 0.438634241995392 NRP2 1 GO:0030325 adrenal gland development 1/244 23/18722 0.260590471422164 0.438634241995392 PBX1 1 GO:0031280 negative regulation of cyclase activity 1/244 23/18722 0.260590471422164 0.438634241995392 AKAP9 1 GO:0035162 embryonic hemopoiesis 1/244 23/18722 0.260590471422164 0.438634241995392 PBX1 1 GO:0035640 exploration behavior 1/244 23/18722 0.260590471422164 0.438634241995392 DPP4 1 GO:0035988 chondrocyte proliferation 1/244 23/18722 0.260590471422164 0.438634241995392 GOLGB1 1 GO:0036303 lymph vessel morphogenesis 1/244 23/18722 0.260590471422164 0.438634241995392 FOXC1 1 GO:0040019 positive regulation of embryonic development 1/244 23/18722 0.260590471422164 0.438634241995392 AMOT 1 GO:0042026 protein refolding 1/244 23/18722 0.260590471422164 0.438634241995392 HSPA5 1 GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment 1/244 23/18722 0.260590471422164 0.438634241995392 CTSL 1 GO:0051131 chaperone-mediated protein complex assembly 1/244 23/18722 0.260590471422164 0.438634241995392 HOPX 1 GO:0051349 positive regulation of lyase activity 1/244 23/18722 0.260590471422164 0.438634241995392 STIM1 1 GO:0051590 positive regulation of neurotransmitter transport 1/244 23/18722 0.260590471422164 0.438634241995392 ITGB1 1 GO:0060575 intestinal epithelial cell differentiation 1/244 23/18722 0.260590471422164 0.438634241995392 IL6ST 1 GO:0071218 cellular response to misfolded protein 1/244 23/18722 0.260590471422164 0.438634241995392 DNAJB14 1 GO:0071305 cellular response to vitamin D 1/244 23/18722 0.260590471422164 0.438634241995392 ATP2B1 1 GO:0071514 genetic imprinting 1/244 23/18722 0.260590471422164 0.438634241995392 DNMT3A 1 GO:0090335 regulation of brown fat cell differentiation 1/244 23/18722 0.260590471422164 0.438634241995392 BMP7 1 GO:2000810 regulation of bicellular tight junction assembly 1/244 23/18722 0.260590471422164 0.438634241995392 GJA1 1 GO:0001937 negative regulation of endothelial cell proliferation 2/244 76/18722 0.260697709865186 0.438634241995392 NR2F2/GJA1 2 GO:0006305 DNA alkylation 2/244 76/18722 0.260697709865186 0.438634241995392 MPHOSPH8/DNMT3A 2 GO:0006306 DNA methylation 2/244 76/18722 0.260697709865186 0.438634241995392 MPHOSPH8/DNMT3A 2 GO:0031100 animal organ regeneration 2/244 76/18722 0.260697709865186 0.438634241995392 GLI3/TGFBR3 2 GO:0043401 steroid hormone mediated signaling pathway 3/244 136/18722 0.26137494943685 0.439548661130752 ISL1/BMP7/DDX5 3 GO:0070371 ERK1 and ERK2 cascade 6/244 330/18722 0.261639519848982 0.439768522876602 LRP1/SEMA6A/APP/ITGAV/P2RY6/GCNT2 6 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 5/244 264/18722 0.261937943997767 0.440045032707905 EFNA5/IL6ST/ISL1/APP/HYAL2 5 GO:0006869 lipid transport 7/244 398/18722 0.263475196697127 0.442401377795994 LRP1/KCNN4/ITGAV/SLC27A2/SREBF2/PLEKHA8/TSKU 7 GO:0030522 intracellular receptor signaling pathway 5/244 265/18722 0.264406645887078 0.443738630431532 NR2F2/ISL1/DCBLD2/PUM1/DDX5 5 GO:0000086 G2/M transition of mitotic cell cycle 3/244 137/18722 0.264889325926636 0.444095063772921 APP/CALM1/PBX1 3 GO:0006986 response to unfolded protein 3/244 137/18722 0.264889325926636 0.444095063772921 TBL2/HSPA5/SERPINH1 3 GO:0033674 positive regulation of kinase activity 8/244 467/18722 0.265486638352951 0.444869502104945 EFNA5/EPHB4/PPP1R9A/CALM1/MET/DAG1/ERP29/ATP2B4 8 GO:0009582 detection of abiotic stimulus 3/244 138/18722 0.268409519614904 0.446449029966613 CDS1/GNAQ/SERPINE2 3 GO:0032273 positive regulation of protein polymerization 3/244 138/18722 0.268409519614904 0.446449029966613 IQGAP2/MET/AKAP9 3 GO:0009913 epidermal cell differentiation 4/244 202/18722 0.27012469427396 0.446449029966613 MCOLN3/PALLD/ASAH1/FOXC1 4 GO:0001779 natural killer cell differentiation 1/244 24/18722 0.270238897807157 0.446449029966613 PBX1 1 GO:0001783 B cell apoptotic process 1/244 24/18722 0.270238897807157 0.446449029966613 SLC39A10 1 GO:0002021 response to dietary excess 1/244 24/18722 0.270238897807157 0.446449029966613 ADRB1 1 GO:0010226 response to lithium ion 1/244 24/18722 0.270238897807157 0.446449029966613 CDH1 1 GO:0022410 circadian sleep/wake cycle process 1/244 24/18722 0.270238897807157 0.446449029966613 ADRB1 1 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress 1/244 24/18722 0.270238897807157 0.446449029966613 HSPA5 1 GO:0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 1/244 24/18722 0.270238897807157 0.446449029966613 PUM1 1 GO:0044321 response to leptin 1/244 24/18722 0.270238897807157 0.446449029966613 LRP2 1 GO:0050855 regulation of B cell receptor signaling pathway 1/244 24/18722 0.270238897807157 0.446449029966613 SLC39A10 1 GO:0051000 positive regulation of nitric-oxide synthase activity 1/244 24/18722 0.270238897807157 0.446449029966613 CALM1 1 GO:0051570 regulation of histone H3-K9 methylation 1/244 24/18722 0.270238897807157 0.446449029966613 JARID2 1 GO:0051647 nucleus localization 1/244 24/18722 0.270238897807157 0.446449029966613 SYNE2 1 GO:0060149 negative regulation of posttranscriptional gene silencing 1/244 24/18722 0.270238897807157 0.446449029966613 KCNQ1OT1 1 GO:0060571 morphogenesis of an epithelial fold 1/244 24/18722 0.270238897807157 0.446449029966613 BMP7 1 GO:0060967 negative regulation of gene silencing by RNA 1/244 24/18722 0.270238897807157 0.446449029966613 KCNQ1OT1 1 GO:0071577 zinc ion transmembrane transport 1/244 24/18722 0.270238897807157 0.446449029966613 SLC39A10 1 GO:0071676 negative regulation of mononuclear cell migration 1/244 24/18722 0.270238897807157 0.446449029966613 MIA3 1 GO:0072010 glomerular epithelium development 1/244 24/18722 0.270238897807157 0.446449029966613 FOXC1 1 GO:0072530 purine-containing compound transmembrane transport 1/244 24/18722 0.270238897807157 0.446449029966613 SLC19A1 1 GO:2000209 regulation of anoikis 1/244 24/18722 0.270238897807157 0.446449029966613 ITGB1 1 GO:2000310 regulation of NMDA receptor activity 1/244 24/18722 0.270238897807157 0.446449029966613 APP 1 GO:2000679 positive regulation of transcription regulatory region DNA binding 1/244 24/18722 0.270238897807157 0.446449029966613 FOXC1 1 GO:0032371 regulation of sterol transport 2/244 78/18722 0.270369315165417 0.446449029966613 LRP1/SREBF2 2 GO:0032374 regulation of cholesterol transport 2/244 78/18722 0.270369315165417 0.446449029966613 LRP1/SREBF2 2 GO:0035050 embryonic heart tube development 2/244 78/18722 0.270369315165417 0.446449029966613 FOLR1/FOXC1 2 GO:0061045 negative regulation of wound healing 2/244 78/18722 0.270369315165417 0.446449029966613 GJA1/SERPINE2 2 GO:0030216 keratinocyte differentiation 3/244 139/18722 0.271935159147368 0.448809107462707 PALLD/ASAH1/FOXC1 3 GO:0060541 respiratory system development 4/244 203/18722 0.27300682539254 0.450351620602352 DAG1/LAMA5/GLI3/HOPX 4 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 2/244 79/18722 0.275204355086082 0.453497430625186 P4HB/CUX1 2 GO:0050772 positive regulation of axonogenesis 2/244 79/18722 0.275204355086082 0.453497430625186 LRP1/MACF1 2 GO:0046165 alcohol biosynthetic process 3/244 140/18722 0.27546587691049 0.453497430625186 P2RY6/DHCR24/ASAH1 3 GO:0050768 negative regulation of neurogenesis 3/244 140/18722 0.27546587691049 0.453497430625186 SEMA6A/SEMA6D/BMP7 3 GO:0071383 cellular response to steroid hormone stimulus 4/244 204/18722 0.275894276758017 0.453975259602826 ISL1/ATP2B1/BMP7/DDX5 4 GO:0007265 Ras protein signal transduction 6/244 337/18722 0.277106500190405 0.454421857871445 JUN/KANK1/MET/ITGB1/HACD3/DHCR24 6 GO:0062197 cellular response to chemical stress 6/244 337/18722 0.277106500190405 0.454421857871445 JUN/BMP7/SOD3/MET/FUT8/P4HB 6 GO:0008584 male gonad development 3/244 141/18722 0.27900130906046 0.454421857871445 LRP2/CTSV/SF1 3 GO:0016241 regulation of macroautophagy 3/244 141/18722 0.27900130906046 0.454421857871445 ATP6V1B1/GAPDH/HTT 3 GO:0010447 response to acidic pH 1/244 25/18722 0.279761932834168 0.454421857871445 LGMN 1 GO:0015012 heparan sulfate proteoglycan biosynthetic process 1/244 25/18722 0.279761932834168 0.454421857871445 EXTL2 1 GO:0016540 protein autoprocessing 1/244 25/18722 0.279761932834168 0.454421857871445 CTSL 1 GO:0021846 cell proliferation in forebrain 1/244 25/18722 0.279761932834168 0.454421857871445 GLI3 1 GO:0032331 negative regulation of chondrocyte differentiation 1/244 25/18722 0.279761932834168 0.454421857871445 EFEMP1 1 GO:0032469 endoplasmic reticulum calcium ion homeostasis 1/244 25/18722 0.279761932834168 0.454421857871445 APP 1 GO:0032878 regulation of establishment or maintenance of cell polarity 1/244 25/18722 0.279761932834168 0.454421857871445 KANK1 1 GO:0034389 lipid droplet organization 1/244 25/18722 0.279761932834168 0.454421857871445 CDS1 1 GO:0036315 cellular response to sterol 1/244 25/18722 0.279761932834168 0.454421857871445 DAG1 1 GO:0048596 embryonic camera-type eye morphogenesis 1/244 25/18722 0.279761932834168 0.454421857871445 BMP7 1 GO:0051450 myoblast proliferation 1/244 25/18722 0.279761932834168 0.454421857871445 MALAT1 1 GO:0051788 response to misfolded protein 1/244 25/18722 0.279761932834168 0.454421857871445 DNAJB14 1 GO:0060740 prostate gland epithelium morphogenesis 1/244 25/18722 0.279761932834168 0.454421857871445 BMP7 1 GO:0072012 glomerulus vasculature development 1/244 25/18722 0.279761932834168 0.454421857871445 BMP7 1 GO:0072202 cell differentiation involved in metanephros development 1/244 25/18722 0.279761932834168 0.454421857871445 LGR4 1 GO:0072207 metanephric epithelium development 1/244 25/18722 0.279761932834168 0.454421857871445 LGR4 1 GO:0098703 calcium ion import across plasma membrane 1/244 25/18722 0.279761932834168 0.454421857871445 ATP2B4 1 GO:1901798 positive regulation of signal transduction by p53 class mediator 1/244 25/18722 0.279761932834168 0.454421857871445 DDX5 1 GO:1902932 positive regulation of alcohol biosynthetic process 1/244 25/18722 0.279761932834168 0.454421857871445 P2RY6 1 GO:1903055 positive regulation of extracellular matrix organization 1/244 25/18722 0.279761932834168 0.454421857871445 DAG1 1 GO:1903792 negative regulation of anion transport 1/244 25/18722 0.279761932834168 0.454421857871445 GABRE 1 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA 1/244 25/18722 0.279761932834168 0.454421857871445 DDX5 1 GO:0009791 post-embryonic development 2/244 80/18722 0.280037815638976 0.454421857871445 FBN1/EFEMP1 2 GO:0071229 cellular response to acid chemical 2/244 80/18722 0.280037815638976 0.454421857871445 SLC38A9/DNMT3A 2 GO:0017038 protein import 4/244 206/18722 0.28168432152446 0.456868055542634 FAM53C/GLI3/CDH1/HYAL2 4 GO:0007009 plasma membrane organization 3/244 142/18722 0.282541095549982 0.45758010841658 FOLR1/SPTBN1/SPESP1 3 GO:0046546 development of primary male sexual characteristics 3/244 142/18722 0.282541095549982 0.45758010841658 LRP2/CTSV/SF1 3 GO:0050729 positive regulation of inflammatory response 3/244 142/18722 0.282541095549982 0.45758010841658 IL6ST/APP/HYAL2 3 GO:0008589 regulation of smoothened signaling pathway 2/244 81/18722 0.284868919715833 0.460895750953337 GLI3/SERPINE2 2 GO:0021954 central nervous system neuron development 2/244 81/18722 0.284868919715833 0.460895750953337 NRP2/TSKU 2 GO:0002573 myeloid leukocyte differentiation 4/244 208/18722 0.287493201028163 0.461436765934842 FBN1/JUN/APP/ITGB8 4 GO:0001573 ganglioside metabolic process 1/244 26/18722 0.289161199475258 0.461436765934842 ITGB8 1 GO:0001963 synaptic transmission, dopaminergic 1/244 26/18722 0.289161199475258 0.461436765934842 SLC6A4 1 GO:0003416 endochondral bone growth 1/244 26/18722 0.289161199475258 0.461436765934842 TSKU 1 GO:0006517 protein deglycosylation 1/244 26/18722 0.289161199475258 0.461436765934842 MAN2A2 1 GO:0007214 gamma-aminobutyric acid signaling pathway 1/244 26/18722 0.289161199475258 0.461436765934842 GABRE 1 GO:0010875 positive regulation of cholesterol efflux 1/244 26/18722 0.289161199475258 0.461436765934842 LRP1 1 GO:0014829 vascular associated smooth muscle contraction 1/244 26/18722 0.289161199475258 0.461436765934842 ATP2B1 1 GO:0021952 central nervous system projection neuron axonogenesis 1/244 26/18722 0.289161199475258 0.461436765934842 TSKU 1 GO:0034063 stress granule assembly 1/244 26/18722 0.289161199475258 0.461436765934842 PRRC2C 1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated 1/244 26/18722 0.289161199475258 0.461436765934842 ARMCX3 1 GO:0042634 regulation of hair cycle 1/244 26/18722 0.289161199475258 0.461436765934842 TSKU 1 GO:0046639 negative regulation of alpha-beta T cell differentiation 1/244 26/18722 0.289161199475258 0.461436765934842 GLI3 1 GO:0047497 mitochondrion transport along microtubule 1/244 26/18722 0.289161199475258 0.461436765934842 ARMCX3 1 GO:0051016 barbed-end actin filament capping 1/244 26/18722 0.289161199475258 0.461436765934842 SVIL 1 GO:0051350 negative regulation of lyase activity 1/244 26/18722 0.289161199475258 0.461436765934842 AKAP9 1 GO:0060219 camera-type eye photoreceptor cell differentiation 1/244 26/18722 0.289161199475258 0.461436765934842 NAGLU 1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 1/244 26/18722 0.289161199475258 0.461436765934842 CALM1 1 GO:0070102 interleukin-6-mediated signaling pathway 1/244 26/18722 0.289161199475258 0.461436765934842 IL6ST 1 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA 1/244 26/18722 0.289161199475258 0.461436765934842 DDX5 1 GO:0072273 metanephric nephron morphogenesis 1/244 26/18722 0.289161199475258 0.461436765934842 LGR4 1 GO:0097066 response to thyroid hormone 1/244 26/18722 0.289161199475258 0.461436765934842 CTSL 1 GO:0097186 amelogenesis 1/244 26/18722 0.289161199475258 0.461436765934842 STIM1 1 GO:1901071 glucosamine-containing compound metabolic process 1/244 26/18722 0.289161199475258 0.461436765934842 EXTL2 1 GO:1902656 calcium ion import into cytosol 1/244 26/18722 0.289161199475258 0.461436765934842 ATP2B4 1 GO:0010821 regulation of mitochondrion organization 3/244 144/18722 0.289632310487077 0.461436765934842 HUWE1/HTT/SREBF2 3 GO:0033135 regulation of peptidyl-serine phosphorylation 3/244 144/18722 0.289632310487077 0.461436765934842 APP/AKAP9/ATP2B4 3 GO:0106106 cold-induced thermogenesis 3/244 144/18722 0.289632310487077 0.461436765934842 ADRB1/GJA1/LGR4 3 GO:0120161 regulation of cold-induced thermogenesis 3/244 144/18722 0.289632310487077 0.461436765934842 ADRB1/GJA1/LGR4 3 GO:0016575 histone deacetylation 2/244 82/18722 0.289696910567127 0.461436765934842 TBL1X/HOPX 2 GO:0043242 negative regulation of protein-containing complex disassembly 2/244 82/18722 0.289696910567127 0.461436765934842 SVIL/SPTBN1 2 GO:2001252 positive regulation of chromosome organization 2/244 82/18722 0.289696910567127 0.461436765934842 MPHOSPH8/NAF1 2 GO:1902905 positive regulation of supramolecular fiber organization 4/244 209/18722 0.290404199652269 0.462339244213836 APP/IQGAP2/MET/AKAP9 4 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 7/244 412/18722 0.291820637827268 0.464369305520776 RNF216/HSPA5/HUWE1/TBL1X/NEMF/SVIP/DNAJB14 7 GO:0043524 negative regulation of neuron apoptotic process 3/244 145/18722 0.293183038034463 0.466076998669629 LRP1/ISL1/LGMN 3 GO:0051961 negative regulation of nervous system development 3/244 145/18722 0.293183038034463 0.466076998669629 SEMA6A/SEMA6D/BMP7 3 GO:0002685 regulation of leukocyte migration 4/244 210/18722 0.293319304092755 0.466076998669629 APP/MIA3/DPP4/LGMN 4 GO:0046785 microtubule polymerization 2/244 83/18722 0.29452105140717 0.466097078461244 MET/AKAP9 2 GO:0051899 membrane depolarization 2/244 83/18722 0.29452105140717 0.466097078461244 JUN/GJA5 2 GO:0030100 regulation of endocytosis 4/244 211/18722 0.296238315641518 0.466097078461244 LRP1/CALM1/ITGAV/AAK1 4 GO:0046474 glycerophospholipid biosynthetic process 4/244 211/18722 0.296238315641518 0.466097078461244 CDS1/PGAP1/SACM1L/PIP5K1B 4 GO:0050807 regulation of synapse organization 4/244 211/18722 0.296238315641518 0.466097078461244 NRP2/PPP1R9A/APP/DAG1 4 GO:0042542 response to hydrogen peroxide 3/244 146/18722 0.296736718160308 0.466097078461244 JUN/LDHA/MET 3 GO:0006401 RNA catabolic process 5/244 278/18722 0.296940954647255 0.466097078461244 KCNQ1OT1/TNRC6B/NAF1/PUM1/DDX5 5 GO:0001958 endochondral ossification 1/244 27/18722 0.298438299781636 0.466097078461244 FOXC1 1 GO:0003171 atrioventricular valve development 1/244 27/18722 0.298438299781636 0.466097078461244 GJA5 1 GO:0003272 endocardial cushion formation 1/244 27/18722 0.298438299781636 0.466097078461244 BMP7 1 GO:0007263 nitric oxide mediated signal transduction 1/244 27/18722 0.298438299781636 0.466097078461244 ATP2B4 1 GO:0008053 mitochondrial fusion 1/244 27/18722 0.298438299781636 0.466097078461244 HUWE1 1 GO:0010561 negative regulation of glycoprotein biosynthetic process 1/244 27/18722 0.298438299781636 0.466097078461244 ITM2B 1 GO:0010586 miRNA metabolic process 1/244 27/18722 0.298438299781636 0.466097078461244 KCNQ1OT1 1 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 1/244 27/18722 0.298438299781636 0.466097078461244 CALM1 1 GO:0018904 ether metabolic process 1/244 27/18722 0.298438299781636 0.466097078461244 NCEH1 1 GO:0031954 positive regulation of protein autophosphorylation 1/244 27/18722 0.298438299781636 0.466097078461244 CALM1 1 GO:0034453 microtubule anchoring 1/244 27/18722 0.298438299781636 0.466097078461244 DAG1 1 GO:0034505 tooth mineralization 1/244 27/18722 0.298438299781636 0.466097078461244 STIM1 1 GO:0035235 ionotropic glutamate receptor signaling pathway 1/244 27/18722 0.298438299781636 0.466097078461244 APP 1 GO:0035459 vesicle cargo loading 1/244 27/18722 0.298438299781636 0.466097078461244 MIA3 1 GO:0036075 replacement ossification 1/244 27/18722 0.298438299781636 0.466097078461244 FOXC1 1 GO:0039529 RIG-I signaling pathway 1/244 27/18722 0.298438299781636 0.466097078461244 PUM1 1 GO:0042403 thyroid hormone metabolic process 1/244 27/18722 0.298438299781636 0.466097078461244 CPQ 1 GO:0042745 circadian sleep/wake cycle 1/244 27/18722 0.298438299781636 0.466097078461244 ADRB1 1 GO:0045606 positive regulation of epidermal cell differentiation 1/244 27/18722 0.298438299781636 0.466097078461244 FOXC1 1 GO:0048520 positive regulation of behavior 1/244 27/18722 0.298438299781636 0.466097078461244 GJA1 1 GO:0060512 prostate gland morphogenesis 1/244 27/18722 0.298438299781636 0.466097078461244 BMP7 1 GO:0061437 renal system vasculature development 1/244 27/18722 0.298438299781636 0.466097078461244 BMP7 1 GO:0061440 kidney vasculature development 1/244 27/18722 0.298438299781636 0.466097078461244 BMP7 1 GO:0070861 regulation of protein exit from endoplasmic reticulum 1/244 27/18722 0.298438299781636 0.466097078461244 SVIP 1 GO:1900746 regulation of vascular endothelial growth factor signaling pathway 1/244 27/18722 0.298438299781636 0.466097078461244 SEMA6A 1 GO:1901018 positive regulation of potassium ion transmembrane transporter activity 1/244 27/18722 0.298438299781636 0.466097078461244 AKAP9 1 GO:1902883 negative regulation of response to oxidative stress 1/244 27/18722 0.298438299781636 0.466097078461244 MET 1 GO:1903205 regulation of hydrogen peroxide-induced cell death 1/244 27/18722 0.298438299781636 0.466097078461244 MET 1 GO:1903421 regulation of synaptic vesicle recycling 1/244 27/18722 0.298438299781636 0.466097078461244 CALM1 1 GO:0043523 regulation of neuron apoptotic process 4/244 212/18722 0.299161036711104 0.466619209599327 JUN/LRP1/ISL1/LGMN 4 GO:0045445 myoblast differentiation 2/244 84/18722 0.299340625025983 0.466619209599327 ISL1/DDX5 2 GO:0061157 mRNA destabilization 2/244 84/18722 0.299340625025983 0.466619209599327 TNRC6B/PUM1 2 GO:0097061 dendritic spine organization 2/244 84/18722 0.299340625025983 0.466619209599327 PPP1R9A/LGMN 2 GO:1902850 microtubule cytoskeleton organization involved in mitosis 3/244 147/18722 0.300293010129664 0.467881854569026 ITGB1/GJA1/HTT 3 GO:0010212 response to ionizing radiation 3/244 148/18722 0.303851577122387 0.471875145933816 HSPA5/XRRA1/DNMT3A 3 GO:0044272 sulfur compound biosynthetic process 3/244 148/18722 0.303851577122387 0.471875145933816 SLC26A2/ACSS1/MTR 3 GO:0044839 cell cycle G2/M phase transition 3/244 148/18722 0.303851577122387 0.471875145933816 APP/CALM1/PBX1 3 GO:0070507 regulation of microtubule cytoskeleton organization 3/244 148/18722 0.303851577122387 0.471875145933816 EFNA5/MET/AKAP9 3 GO:0032092 positive regulation of protein binding 2/244 85/18722 0.304154933407811 0.471875145933816 LRP1/APP 2 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 2/244 85/18722 0.304154933407811 0.471875145933816 IL6ST/ISL1 2 GO:0055072 iron ion homeostasis 2/244 85/18722 0.304154933407811 0.471875145933816 SLC46A1/HYAL2 2 GO:0071277 cellular response to calcium ion 2/244 85/18722 0.304154933407811 0.471875145933816 HSPA5/LGMN 2 GO:0072384 organelle transport along microtubule 2/244 85/18722 0.304154933407811 0.471875145933816 ARMCX3/HTT 2 GO:0007249 I-kappaB kinase/NF-kappaB signaling 5/244 281/18722 0.304547374311446 0.471875145933816 MAPKBP1/GAPDH/HACD3/WLS/GJA1 5 GO:0000082 G1/S transition of mitotic cell cycle 4/244 214/18722 0.305016822800948 0.471875145933816 ADAMTS1/LATS2/ITGB1/CTDSPL 4 GO:0032368 regulation of lipid transport 3/244 149/18722 0.307412086246307 0.471875145933816 LRP1/ITGAV/SREBF2 3 GO:0000423 mitophagy 1/244 28/18722 0.307594815152232 0.471875145933816 HUWE1 1 GO:0002675 positive regulation of acute inflammatory response 1/244 28/18722 0.307594815152232 0.471875145933816 IL6ST 1 GO:0003156 regulation of animal organ formation 1/244 28/18722 0.307594815152232 0.471875145933816 BMP7 1 GO:0006829 zinc ion transport 1/244 28/18722 0.307594815152232 0.471875145933816 SLC39A10 1 GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway 1/244 28/18722 0.307594815152232 0.471875145933816 LRP1 1 GO:0009065 glutamine family amino acid catabolic process 1/244 28/18722 0.307594815152232 0.471875145933816 ATP2B4 1 GO:0009312 oligosaccharide biosynthetic process 1/244 28/18722 0.307594815152232 0.471875145933816 FUT8 1 GO:0010460 positive regulation of heart rate 1/244 28/18722 0.307594815152232 0.471875145933816 ADRB1 1 GO:0010464 regulation of mesenchymal cell proliferation 1/244 28/18722 0.307594815152232 0.471875145933816 LRP5 1 GO:0010884 positive regulation of lipid storage 1/244 28/18722 0.307594815152232 0.471875145933816 SREBF2 1 GO:0015740 C4-dicarboxylate transport 1/244 28/18722 0.307594815152232 0.471875145933816 SLC1A3 1 GO:0019098 reproductive behavior 1/244 28/18722 0.307594815152232 0.471875145933816 APP 1 GO:0032801 receptor catabolic process 1/244 28/18722 0.307594815152232 0.471875145933816 LGMN 1 GO:0032958 inositol phosphate biosynthetic process 1/244 28/18722 0.307594815152232 0.471875145933816 P2RY6 1 GO:0042983 amyloid precursor protein biosynthetic process 1/244 28/18722 0.307594815152232 0.471875145933816 ITM2B 1 GO:0042984 regulation of amyloid precursor protein biosynthetic process 1/244 28/18722 0.307594815152232 0.471875145933816 ITM2B 1 GO:0045671 negative regulation of osteoclast differentiation 1/244 28/18722 0.307594815152232 0.471875145933816 FBN1 1 GO:0060325 face morphogenesis 1/244 28/18722 0.307594815152232 0.471875145933816 ANKRD11 1 GO:0060765 regulation of androgen receptor signaling pathway 1/244 28/18722 0.307594815152232 0.471875145933816 DDX5 1 GO:0071280 cellular response to copper ion 1/244 28/18722 0.307594815152232 0.471875145933816 APP 1 GO:1903671 negative regulation of sprouting angiogenesis 1/244 28/18722 0.307594815152232 0.471875145933816 SEMA6A 1 GO:0032102 negative regulation of response to external stimulus 7/244 420/18722 0.308326524921818 0.47277692995478 SEMA6A/ISL1/SEMA6D/MAPKBP1/DPP4/GJA1/SERPINE2 7 GO:0006493 protein O-linked glycosylation 2/244 86/18722 0.3089632973562 0.473091050844582 GALNT11/TMTC3 2 GO:0009798 axis specification 2/244 86/18722 0.3089632973562 0.473091050844582 PGAP1/WLS 2 GO:0046928 regulation of neurotransmitter secretion 2/244 86/18722 0.3089632973562 0.473091050844582 PPP1R9A/CALM1 2 GO:0051146 striated muscle cell differentiation 5/244 283/18722 0.309634949898581 0.473898670408354 ISL1/ITGB1/RCAN1/HOPX/KRT19 5 GO:0007029 endoplasmic reticulum organization 2/244 87/18722 0.313765056125523 0.475943135529241 MIA3/LMAN1 2 GO:0061014 positive regulation of mRNA catabolic process 2/244 87/18722 0.313765056125523 0.475943135529241 TNRC6B/PUM1 2 GO:1901606 alpha-amino acid catabolic process 2/244 87/18722 0.313765056125523 0.475943135529241 ATP2B4/GLDC 2 GO:1901879 regulation of protein depolymerization 2/244 87/18722 0.313765056125523 0.475943135529241 SVIL/SPTBN1 2 GO:0070374 positive regulation of ERK1 and ERK2 cascade 4/244 217/18722 0.313823450544059 0.475943135529241 LRP1/APP/P2RY6/GCNT2 4 GO:0071333 cellular response to glucose stimulus 3/244 151/18722 0.314537619025893 0.475943135529241 EFNA5/LRP5/LRP1 3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 1/244 29/18722 0.316632306598838 0.475943135529241 TNRC6B 1 GO:0001773 myeloid dendritic cell activation 1/244 29/18722 0.316632306598838 0.475943135529241 ITGB8 1 GO:0002360 T cell lineage commitment 1/244 29/18722 0.316632306598838 0.475943135529241 CTSL 1 GO:0003209 cardiac atrium morphogenesis 1/244 29/18722 0.316632306598838 0.475943135529241 ISL1 1 GO:0006656 phosphatidylcholine biosynthetic process 1/244 29/18722 0.316632306598838 0.475943135529241 CDS1 1 GO:0009310 amine catabolic process 1/244 29/18722 0.316632306598838 0.475943135529241 ATP2B4 1 GO:0010955 negative regulation of protein processing 1/244 29/18722 0.316632306598838 0.475943135529241 SERPINE2 1 GO:0015701 bicarbonate transport 1/244 29/18722 0.316632306598838 0.475943135529241 SLC26A2 1 GO:0019082 viral protein processing 1/244 29/18722 0.316632306598838 0.475943135529241 FUT8 1 GO:0030970 retrograde protein transport, ER to cytosol 1/244 29/18722 0.316632306598838 0.475943135529241 SVIP 1 GO:0032372 negative regulation of sterol transport 1/244 29/18722 0.316632306598838 0.475943135529241 SREBF2 1 GO:0032375 negative regulation of cholesterol transport 1/244 29/18722 0.316632306598838 0.475943135529241 SREBF2 1 GO:0033028 myeloid cell apoptotic process 1/244 29/18722 0.316632306598838 0.475943135529241 CTSL 1 GO:0035066 positive regulation of histone acetylation 1/244 29/18722 0.316632306598838 0.475943135529241 ISL1 1 GO:0048265 response to pain 1/244 29/18722 0.316632306598838 0.475943135529241 VWA1 1 GO:0048679 regulation of axon regeneration 1/244 29/18722 0.316632306598838 0.475943135529241 LRP1 1 GO:0051654 establishment of mitochondrion localization 1/244 29/18722 0.316632306598838 0.475943135529241 ARMCX3 1 GO:0051873 killing by host of symbiont cells 1/244 29/18722 0.316632306598838 0.475943135529241 GAPDH 1 GO:0051883 killing of cells in other organism involved in symbiotic interaction 1/244 29/18722 0.316632306598838 0.475943135529241 GAPDH 1 GO:0060441 epithelial tube branching involved in lung morphogenesis 1/244 29/18722 0.316632306598838 0.475943135529241 DAG1 1 GO:0060969 negative regulation of gene silencing 1/244 29/18722 0.316632306598838 0.475943135529241 KCNQ1OT1 1 GO:0062098 regulation of programmed necrotic cell death 1/244 29/18722 0.316632306598838 0.475943135529241 ASAH1 1 GO:0090025 regulation of monocyte chemotaxis 1/244 29/18722 0.316632306598838 0.475943135529241 LGMN 1 GO:0090114 COPII-coated vesicle budding 1/244 29/18722 0.316632306598838 0.475943135529241 MIA3 1 GO:0095500 acetylcholine receptor signaling pathway 1/244 29/18722 0.316632306598838 0.475943135529241 GNAQ 1 GO:0098868 bone growth 1/244 29/18722 0.316632306598838 0.475943135529241 TSKU 1 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 1/244 29/18722 0.316632306598838 0.475943135529241 P4HB 1 GO:1903318 negative regulation of protein maturation 1/244 29/18722 0.316632306598838 0.475943135529241 SERPINE2 1 GO:1903513 endoplasmic reticulum to cytosol transport 1/244 29/18722 0.316632306598838 0.475943135529241 SVIP 1 GO:1903902 positive regulation of viral life cycle 1/244 29/18722 0.316632306598838 0.475943135529241 P4HB 1 GO:2000406 positive regulation of T cell migration 1/244 29/18722 0.316632306598838 0.475943135529241 APP 1 GO:0044772 mitotic cell cycle phase transition 7/244 424/18722 0.316649163474147 0.475943135529241 ADAMTS1/LATS2/APP/CALM1/ITGB1/PBX1/CTDSPL 7 GO:0042445 hormone metabolic process 4/244 218/18722 0.316764344918579 0.475943135529241 CTSL/ENPEP/CPQ/RDH14 4 GO:0050803 regulation of synapse structure or activity 4/244 218/18722 0.316764344918579 0.475943135529241 NRP2/PPP1R9A/APP/DAG1 4 GO:0031056 regulation of histone modification 3/244 152/18722 0.318101996631727 0.477734534246735 ISL1/JARID2/MLLT6 3 GO:0007260 tyrosine phosphorylation of STAT protein 2/244 88/18722 0.318559567058839 0.477766653288611 IL6ST/ISL1 2 GO:0031110 regulation of microtubule polymerization or depolymerization 2/244 88/18722 0.318559567058839 0.477766653288611 MET/AKAP9 2 GO:0050779 RNA destabilization 2/244 88/18722 0.318559567058839 0.477766653288611 TNRC6B/PUM1 2 GO:0097191 extrinsic apoptotic signaling pathway 4/244 219/18722 0.319707598892241 0.479269694324773 ITGAV/HTT/PDIA3/HYAL2 4 GO:2001233 regulation of apoptotic signaling pathway 6/244 356/18722 0.320051207640494 0.479566013819727 ITGAV/ERP29/P4HB/HTT/PDIA3/HYAL2 6 GO:0071331 cellular response to hexose stimulus 3/244 153/18722 0.32166702428381 0.481767475750502 EFNA5/LRP5/LRP1 3 GO:0032103 positive regulation of response to external stimulus 7/244 427/18722 0.322917999516212 0.482963840684349 LRP1/IL6ST/APP/MET/LGMN/PUM1/HYAL2 7 GO:0071326 cellular response to monosaccharide stimulus 3/244 154/18722 0.325232388868711 0.482963840684349 EFNA5/LRP5/LRP1 3 GO:0003299 muscle hypertrophy in response to stress 1/244 30/18722 0.325552315007862 0.482963840684349 ATP2B4 1 GO:0007176 regulation of epidermal growth factor-activated receptor activity 1/244 30/18722 0.325552315007862 0.482963840684349 APP 1 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 1/244 30/18722 0.325552315007862 0.482963840684349 CALM1 1 GO:0014887 cardiac muscle adaptation 1/244 30/18722 0.325552315007862 0.482963840684349 ATP2B4 1 GO:0014898 cardiac muscle hypertrophy in response to stress 1/244 30/18722 0.325552315007862 0.482963840684349 ATP2B4 1 GO:0019674 NAD metabolic process 1/244 30/18722 0.325552315007862 0.482963840684349 LDHA 1 GO:0032480 negative regulation of type I interferon production 1/244 30/18722 0.325552315007862 0.482963840684349 RNF216 1 GO:0044030 regulation of DNA methylation 1/244 30/18722 0.325552315007862 0.482963840684349 MPHOSPH8 1 GO:0045070 positive regulation of viral genome replication 1/244 30/18722 0.325552315007862 0.482963840684349 HACD3 1 GO:0060218 hematopoietic stem cell differentiation 1/244 30/18722 0.325552315007862 0.482963840684349 FOXC1 1 GO:0060292 long-term synaptic depression 1/244 30/18722 0.325552315007862 0.482963840684349 PPP1R9A 1 GO:0060603 mammary gland duct morphogenesis 1/244 30/18722 0.325552315007862 0.482963840684349 LRP5 1 GO:0061311 cell surface receptor signaling pathway involved in heart development 1/244 30/18722 0.325552315007862 0.482963840684349 GALNT11 1 GO:0070229 negative regulation of lymphocyte apoptotic process 1/244 30/18722 0.325552315007862 0.482963840684349 SLC39A10 1 GO:0090151 establishment of protein localization to mitochondrial membrane 1/244 30/18722 0.325552315007862 0.482963840684349 CALM1 1 GO:0090314 positive regulation of protein targeting to membrane 1/244 30/18722 0.325552315007862 0.482963840684349 TCAF1 1 GO:0099068 postsynapse assembly 1/244 30/18722 0.325552315007862 0.482963840684349 NLGN4X 1 GO:1900101 regulation of endoplasmic reticulum unfolded protein response 1/244 30/18722 0.325552315007862 0.482963840684349 HSPA5 1 GO:2000648 positive regulation of stem cell proliferation 1/244 30/18722 0.325552315007862 0.482963840684349 GJA1 1 GO:0061097 regulation of protein tyrosine kinase activity 2/244 90/18722 0.328124363103908 0.48634039565153 APP/HYAL2 2 GO:0099175 regulation of postsynapse organization 2/244 90/18722 0.328124363103908 0.48634039565153 NRP2/PPP1R9A 2 GO:0015931 nucleobase-containing compound transport 4/244 222/18722 0.328549646273473 0.486751189204073 SLC35D1/GJA1/SLC35A4/SLC19A1 4 GO:1903364 positive regulation of cellular protein catabolic process 3/244 155/18722 0.32879778124549 0.486899283088184 LRP2/LRP1/TMTC3 3 GO:0016236 macroautophagy 5/244 291/18722 0.330096255341566 0.488601934708281 CALM1/ATP6V1B1/GAPDH/HUWE1/HTT 5 GO:0001764 neuron migration 3/244 156/18722 0.33236289624783 0.491586131345065 NR2F2/NRP2/SEMA6A 3 GO:0055006 cardiac cell development 2/244 91/18722 0.332893450172785 0.491586131345065 ISL1/TGFBR3 2 GO:0016577 histone demethylation 1/244 31/18722 0.334356361398728 0.491586131345065 JARID2 1 GO:0030149 sphingolipid catabolic process 1/244 31/18722 0.334356361398728 0.491586131345065 ASAH1 1 GO:0030201 heparan sulfate proteoglycan metabolic process 1/244 31/18722 0.334356361398728 0.491586131345065 EXTL2 1 GO:0033238 regulation of cellular amine metabolic process 1/244 31/18722 0.334356361398728 0.491586131345065 ATP2B4 1 GO:0036474 cell death in response to hydrogen peroxide 1/244 31/18722 0.334356361398728 0.491586131345065 MET 1 GO:0042133 neurotransmitter metabolic process 1/244 31/18722 0.334356361398728 0.491586131345065 SLC6A4 1 GO:0048566 embryonic digestive tract development 1/244 31/18722 0.334356361398728 0.491586131345065 GLI3 1 GO:0060045 positive regulation of cardiac muscle cell proliferation 1/244 31/18722 0.334356361398728 0.491586131345065 TGFBR3 1 GO:0060055 angiogenesis involved in wound healing 1/244 31/18722 0.334356361398728 0.491586131345065 DAG1 1 GO:0061099 negative regulation of protein tyrosine kinase activity 1/244 31/18722 0.334356361398728 0.491586131345065 HYAL2 1 GO:0070723 response to cholesterol 1/244 31/18722 0.334356361398728 0.491586131345065 DAG1 1 GO:0071480 cellular response to gamma radiation 1/244 31/18722 0.334356361398728 0.491586131345065 HSPA5 1 GO:2000144 positive regulation of DNA-templated transcription, initiation 1/244 31/18722 0.334356361398728 0.491586131345065 JUN 1 GO:0051017 actin filament bundle assembly 3/244 157/18722 0.335927432684771 0.493454422799356 PPP1R9A/TACSTD2/MET 3 GO:1990845 adaptive thermogenesis 3/244 157/18722 0.335927432684771 0.493454422799356 ADRB1/GJA1/LGR4 3 GO:0008037 cell recognition 4/244 225/18722 0.337406245799942 0.495103706028508 PALLD/APP/FOLR1/SPESP1 4 GO:0006497 protein lipidation 2/244 92/18722 0.337652892638431 0.495103706028508 PGAP1/SVIP 2 GO:0031058 positive regulation of histone modification 2/244 92/18722 0.337652892638431 0.495103706028508 ISL1/JARID2 2 GO:0032465 regulation of cytokinesis 2/244 92/18722 0.337652892638431 0.495103706028508 SVIL/CALM1 2 GO:0006506 GPI anchor biosynthetic process 1/244 32/18722 0.343045947178981 0.49922452720555 PGAP1 1 GO:0010743 regulation of macrophage derived foam cell differentiation 1/244 32/18722 0.343045947178981 0.49922452720555 ITGAV 1 GO:0030431 sleep 1/244 32/18722 0.343045947178981 0.49922452720555 ADRB1 1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 1/244 32/18722 0.343045947178981 0.49922452720555 TGFBR3 1 GO:0042044 fluid transport 1/244 32/18722 0.343045947178981 0.49922452720555 HYAL2 1 GO:0045684 positive regulation of epidermis development 1/244 32/18722 0.343045947178981 0.49922452720555 FOXC1 1 GO:0046856 phosphatidylinositol dephosphorylation 1/244 32/18722 0.343045947178981 0.49922452720555 SACM1L 1 GO:0060317 cardiac epithelial to mesenchymal transition 1/244 32/18722 0.343045947178981 0.49922452720555 TGFBR3 1 GO:0060323 head morphogenesis 1/244 32/18722 0.343045947178981 0.49922452720555 ANKRD11 1 GO:0061036 positive regulation of cartilage development 1/244 32/18722 0.343045947178981 0.49922452720555 GLI3 1 GO:0061037 negative regulation of cartilage development 1/244 32/18722 0.343045947178981 0.49922452720555 EFEMP1 1 GO:0090022 regulation of neutrophil chemotaxis 1/244 32/18722 0.343045947178981 0.49922452720555 DPP4 1 GO:1901185 negative regulation of ERBB signaling pathway 1/244 32/18722 0.343045947178981 0.49922452720555 LGMN 1 GO:1901532 regulation of hematopoietic progenitor cell differentiation 1/244 32/18722 0.343045947178981 0.49922452720555 FOXC1 1 GO:1901889 negative regulation of cell junction assembly 1/244 32/18722 0.343045947178981 0.49922452720555 LRP1 1 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/244 32/18722 0.343045947178981 0.49922452720555 ERP29 1 GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 1/244 32/18722 0.343045947178981 0.49922452720555 TGFBR3 1 GO:0046777 protein autophosphorylation 4/244 227/18722 0.343316309568437 0.499396809757363 EPHB4/CALM1/AAK1/SLK 4 GO:0043271 negative regulation of ion transport 3/244 160/18722 0.346614618302152 0.503177816694896 CALM1/GABRE/SERPINE2 3 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 2/244 94/18722 0.347140630081354 0.503177816694896 NR2F2/LATS2 2 GO:0010389 regulation of G2/M transition of mitotic cell cycle 2/244 94/18722 0.347140630081354 0.503177816694896 APP/PBX1 2 GO:0019080 viral gene expression 2/244 94/18722 0.347140630081354 0.503177816694896 JUN/FUT8 2 GO:0048704 embryonic skeletal system morphogenesis 2/244 94/18722 0.347140630081354 0.503177816694896 BMP7/GLI3 2 GO:0051702 biological process involved in interaction with symbiont 2/244 94/18722 0.347140630081354 0.503177816694896 JUN/GAPDH 2 GO:1902414 protein localization to cell junction 2/244 94/18722 0.347140630081354 0.503177816694896 DAG1/VCL 2 GO:1903035 negative regulation of response to wounding 2/244 94/18722 0.347140630081354 0.503177816694896 GJA1/SERPINE2 2 GO:0044782 cilium organization 6/244 368/18722 0.347683191147309 0.503742048549408 GALNT11/DZIP1/LAMA5/UNC119B/IFT27/HTT 6 GO:0061572 actin filament bundle organization 3/244 161/18722 0.350173908026763 0.504246742875184 PPP1R9A/TACSTD2/MET 3 GO:0001975 response to amphetamine 1/244 33/18722 0.35162255439612 0.504246742875184 CALM1 1 GO:0006482 protein demethylation 1/244 33/18722 0.35162255439612 0.504246742875184 JARID2 1 GO:0006505 GPI anchor metabolic process 1/244 33/18722 0.35162255439612 0.504246742875184 PGAP1 1 GO:0006891 intra-Golgi vesicle-mediated transport 1/244 33/18722 0.35162255439612 0.504246742875184 CUX1 1 GO:0008214 protein dealkylation 1/244 33/18722 0.35162255439612 0.504246742875184 JARID2 1 GO:0010165 response to X-ray 1/244 33/18722 0.35162255439612 0.504246742875184 XRRA1 1 GO:0021696 cerebellar cortex morphogenesis 1/244 33/18722 0.35162255439612 0.504246742875184 SERPINE2 1 GO:0050901 leukocyte tethering or rolling 1/244 33/18722 0.35162255439612 0.504246742875184 ITGB1 1 GO:0050974 detection of mechanical stimulus involved in sensory perception 1/244 33/18722 0.35162255439612 0.504246742875184 SERPINE2 1 GO:0070570 regulation of neuron projection regeneration 1/244 33/18722 0.35162255439612 0.504246742875184 LRP1 1 GO:0071353 cellular response to interleukin-4 1/244 33/18722 0.35162255439612 0.504246742875184 HSPA5 1 GO:0071539 protein localization to centrosome 1/244 33/18722 0.35162255439612 0.504246742875184 GOLGB1 1 GO:0099174 regulation of presynapse organization 1/244 33/18722 0.35162255439612 0.504246742875184 APP 1 GO:1900181 negative regulation of protein localization to nucleus 1/244 33/18722 0.35162255439612 0.504246742875184 LATS2 1 GO:1902275 regulation of chromatin organization 1/244 33/18722 0.35162255439612 0.504246742875184 MPHOSPH8 1 GO:1902692 regulation of neuroblast proliferation 1/244 33/18722 0.35162255439612 0.504246742875184 GLI3 1 GO:1905606 regulation of presynapse assembly 1/244 33/18722 0.35162255439612 0.504246742875184 APP 1 GO:2000036 regulation of stem cell population maintenance 1/244 33/18722 0.35162255439612 0.504246742875184 BMP7 1 GO:0032479 regulation of type I interferon production 2/244 95/18722 0.351867858007546 0.504246742875184 GAPDH/RNF216 2 GO:0032606 type I interferon production 2/244 95/18722 0.351867858007546 0.504246742875184 GAPDH/RNF216 2 GO:0036473 cell death in response to oxidative stress 2/244 95/18722 0.351867858007546 0.504246742875184 MET/P4HB 2 GO:0042982 amyloid precursor protein metabolic process 2/244 95/18722 0.351867858007546 0.504246742875184 ITM2B/DHCR24 2 GO:0048709 oligodendrocyte differentiation 2/244 95/18722 0.351867858007546 0.504246742875184 DAG1/GLI3 2 GO:0050764 regulation of phagocytosis 2/244 95/18722 0.351867858007546 0.504246742875184 LRP1/ITGAV 2 GO:0006913 nucleocytoplasmic transport 5/244 301/18722 0.355848126081787 0.50922761645561 FAM53C/GLI3/CDH1/NEMF/HYAL2 5 GO:0051169 nuclear transport 5/244 301/18722 0.355848126081787 0.50922761645561 FAM53C/GLI3/CDH1/NEMF/HYAL2 5 GO:0015914 phospholipid transport 2/244 96/18722 0.356583306592927 0.50922761645561 KCNN4/PLEKHA8 2 GO:0030510 regulation of BMP signaling pathway 2/244 96/18722 0.356583306592927 0.50922761645561 LRP2/FBN1 2 GO:0034620 cellular response to unfolded protein 2/244 96/18722 0.356583306592927 0.50922761645561 TBL2/HSPA5 2 GO:0035282 segmentation 2/244 96/18722 0.356583306592927 0.50922761645561 NRP2/FOXC1 2 GO:0042158 lipoprotein biosynthetic process 2/244 96/18722 0.356583306592927 0.50922761645561 PGAP1/SVIP 2 GO:1901655 cellular response to ketone 2/244 96/18722 0.356583306592927 0.50922761645561 ATP2B1/P2RY6 2 GO:0071322 cellular response to carbohydrate stimulus 3/244 163/18722 0.357286135212987 0.509581397377569 EFNA5/LRP5/LRP1 3 GO:0000096 sulfur amino acid metabolic process 1/244 34/18722 0.360087645986219 0.509581397377569 MTR 1 GO:0009649 entrainment of circadian clock 1/244 34/18722 0.360087645986219 0.509581397377569 GNAQ 1 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 1/244 34/18722 0.360087645986219 0.509581397377569 CALM1 1 GO:0032212 positive regulation of telomere maintenance via telomerase 1/244 34/18722 0.360087645986219 0.509581397377569 NAF1 1 GO:0032743 positive regulation of interleukin-2 production 1/244 34/18722 0.360087645986219 0.509581397377569 SPTBN1 1 GO:0032770 positive regulation of monooxygenase activity 1/244 34/18722 0.360087645986219 0.509581397377569 CALM1 1 GO:0034383 low-density lipoprotein particle clearance 1/244 34/18722 0.360087645986219 0.509581397377569 NCEH1 1 GO:0035590 purinergic nucleotide receptor signaling pathway 1/244 34/18722 0.360087645986219 0.509581397377569 P2RY6 1 GO:0035909 aorta morphogenesis 1/244 34/18722 0.360087645986219 0.509581397377569 LRP1 1 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus 1/244 34/18722 0.360087645986219 0.509581397377569 PUM1 1 GO:0043276 anoikis 1/244 34/18722 0.360087645986219 0.509581397377569 ITGB1 1 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 1/244 34/18722 0.360087645986219 0.509581397377569 DDX5 1 GO:0048261 negative regulation of receptor-mediated endocytosis 1/244 34/18722 0.360087645986219 0.509581397377569 ITGAV 1 GO:0048741 skeletal muscle fiber development 1/244 34/18722 0.360087645986219 0.509581397377569 RCAN1 1 GO:0048854 brain morphogenesis 1/244 34/18722 0.360087645986219 0.509581397377569 SLC6A4 1 GO:0051973 positive regulation of telomerase activity 1/244 34/18722 0.360087645986219 0.509581397377569 NAF1 1 GO:0070050 neuron cellular homeostasis 1/244 34/18722 0.360087645986219 0.509581397377569 ATP2B1 1 GO:0098751 bone cell development 1/244 34/18722 0.360087645986219 0.509581397377569 FBN1 1 GO:1990000 amyloid fibril formation 1/244 34/18722 0.360087645986219 0.509581397377569 APP 1 GO:2000758 positive regulation of peptidyl-lysine acetylation 1/244 34/18722 0.360087645986219 0.509581397377569 ISL1 1 GO:0010596 negative regulation of endothelial cell migration 2/244 97/18722 0.36128648068019 0.510618226028002 NR2F2/ATP2B4 2 GO:0120162 positive regulation of cold-induced thermogenesis 2/244 97/18722 0.36128648068019 0.510618226028002 ADRB1/GJA1 2 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 2/244 97/18722 0.36128648068019 0.510618226028002 ITGAV/HTT 2 GO:0032635 interleukin-6 production 3/244 165/18722 0.364388063127755 0.514559164348003 ISL1/APP/HYAL2 3 GO:0032675 regulation of interleukin-6 production 3/244 165/18722 0.364388063127755 0.514559164348003 ISL1/APP/HYAL2 3 GO:0032642 regulation of chemokine production 2/244 98/18722 0.365976899906632 0.515192595974306 LRP1/APP 2 GO:0043473 pigmentation 2/244 98/18722 0.365976899906632 0.515192595974306 GLI3/HPS6 2 GO:1904029 regulation of cyclin-dependent protein kinase activity 2/244 98/18722 0.365976899906632 0.515192595974306 NR2F2/LATS2 2 GO:0045930 negative regulation of mitotic cell cycle 4/244 235/18722 0.366971381449565 0.515192595974306 BMP7/BTG3/FOXC1/CTDSPL 4 GO:0006084 acetyl-CoA metabolic process 1/244 35/18722 0.368442666019361 0.515192595974306 ACSS1 1 GO:0007020 microtubule nucleation 1/244 35/18722 0.368442666019361 0.515192595974306 AKAP9 1 GO:0010664 negative regulation of striated muscle cell apoptotic process 1/244 35/18722 0.368442666019361 0.515192595974306 BMP7 1 GO:0010765 positive regulation of sodium ion transport 1/244 35/18722 0.368442666019361 0.515192595974306 MLLT6 1 GO:0015695 organic cation transport 1/244 35/18722 0.368442666019361 0.515192595974306 SLC19A3 1 GO:0021955 central nervous system neuron axonogenesis 1/244 35/18722 0.368442666019361 0.515192595974306 TSKU 1 GO:0031076 embryonic camera-type eye development 1/244 35/18722 0.368442666019361 0.515192595974306 BMP7 1 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 1/244 35/18722 0.368442666019361 0.515192595974306 SVIP 1 GO:0033146 regulation of intracellular estrogen receptor signaling pathway 1/244 35/18722 0.368442666019361 0.515192595974306 ISL1 1 GO:0039694 viral RNA genome replication 1/244 35/18722 0.368442666019361 0.515192595974306 MPHOSPH8 1 GO:0044273 sulfur compound catabolic process 1/244 35/18722 0.368442666019361 0.515192595974306 GNS 1 GO:0046627 negative regulation of insulin receptor signaling pathway 1/244 35/18722 0.368442666019361 0.515192595974306 KANK1 1 GO:0070536 protein K63-linked deubiquitination 1/244 35/18722 0.368442666019361 0.515192595974306 USP25 1 GO:0071108 protein K48-linked deubiquitination 1/244 35/18722 0.368442666019361 0.515192595974306 USP25 1 GO:0097421 liver regeneration 1/244 35/18722 0.368442666019361 0.515192595974306 GLI3 1 GO:0097502 mannosylation 1/244 35/18722 0.368442666019361 0.515192595974306 TMTC3 1 GO:1903514 release of sequestered calcium ion into cytosol by endoplasmic reticulum 1/244 35/18722 0.368442666019361 0.515192595974306 CALM1 1 GO:1905508 protein localization to microtubule organizing center 1/244 35/18722 0.368442666019361 0.515192595974306 GOLGB1 1 GO:2000403 positive regulation of lymphocyte migration 1/244 35/18722 0.368442666019361 0.515192595974306 APP 1 GO:0021510 spinal cord development 2/244 99/18722 0.370654098405412 0.517844118775588 ISL1/GLI3 2 GO:0032602 chemokine production 2/244 99/18722 0.370654098405412 0.517844118775588 LRP1/APP 2 GO:0055088 lipid homeostasis 3/244 167/18722 0.371477551342623 0.518774004977416 LRP5/SREBF2/TSKU 3 GO:0019318 hexose metabolic process 4/244 237/18722 0.372882032543795 0.520293146046246 LRP5/GAPDH/MAN2A2/FUT8 4 GO:1901617 organic hydroxy compound biosynthetic process 4/244 237/18722 0.372882032543795 0.520293146046246 P2RY6/SLC27A2/DHCR24/ASAH1 4 GO:0006909 phagocytosis 5/244 308/18722 0.373930631171672 0.52095967392644 LRP1/MET/ITGAV/ITGB1/P2RY6 5 GO:1902806 regulation of cell cycle G1/S phase transition 3/244 168/18722 0.375016978817381 0.52095967392644 ADAMTS1/ATP2B4/CTDSPL 3 GO:0006664 glycolipid metabolic process 2/244 100/18722 0.375317624512037 0.52095967392644 PGAP1/ITGB8 2 GO:0019218 regulation of steroid metabolic process 2/244 100/18722 0.375317624512037 0.52095967392644 ASAH1/SF1 2 GO:0044728 DNA methylation or demethylation 2/244 100/18722 0.375317624512037 0.52095967392644 MPHOSPH8/DNMT3A 2 GO:0070372 regulation of ERK1 and ERK2 cascade 5/244 309/18722 0.376514835289147 0.52095967392644 LRP1/SEMA6A/APP/P2RY6/GCNT2 5 GO:0006699 bile acid biosynthetic process 1/244 36/18722 0.376689039941942 0.52095967392644 SLC27A2 1 GO:0030224 monocyte differentiation 1/244 36/18722 0.376689039941942 0.52095967392644 JUN 1 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 1/244 36/18722 0.376689039941942 0.52095967392644 LRP1 1 GO:0036314 response to sterol 1/244 36/18722 0.376689039941942 0.52095967392644 DAG1 1 GO:0038179 neurotrophin signaling pathway 1/244 36/18722 0.376689039941942 0.52095967392644 KIDINS220 1 GO:0044060 regulation of endocrine process 1/244 36/18722 0.376689039941942 0.52095967392644 GJA1 1 GO:0045746 negative regulation of Notch signaling pathway 1/244 36/18722 0.376689039941942 0.52095967392644 BMP7 1 GO:0046466 membrane lipid catabolic process 1/244 36/18722 0.376689039941942 0.52095967392644 ASAH1 1 GO:0051354 negative regulation of oxidoreductase activity 1/244 36/18722 0.376689039941942 0.52095967392644 ATP2B4 1 GO:0051955 regulation of amino acid transport 1/244 36/18722 0.376689039941942 0.52095967392644 ITGB1 1 GO:0070670 response to interleukin-4 1/244 36/18722 0.376689039941942 0.52095967392644 HSPA5 1 GO:0090313 regulation of protein targeting to membrane 1/244 36/18722 0.376689039941942 0.52095967392644 TCAF1 1 GO:0090322 regulation of superoxide metabolic process 1/244 36/18722 0.376689039941942 0.52095967392644 BMP7 1 GO:0097009 energy homeostasis 1/244 36/18722 0.376689039941942 0.52095967392644 TSKU 1 GO:1903539 protein localization to postsynaptic membrane 1/244 36/18722 0.376689039941942 0.52095967392644 DAG1 1 GO:0006476 protein deacetylation 2/244 101/18722 0.379967040475982 0.524609955884066 TBL1X/HOPX 2 GO:0051963 regulation of synapse assembly 2/244 101/18722 0.379967040475982 0.524609955884066 PPP1R9A/APP 2 GO:0098869 cellular oxidant detoxification 2/244 101/18722 0.379967040475982 0.524609955884066 BMP7/SOD3 2 GO:1903509 liposaccharide metabolic process 2/244 101/18722 0.379967040475982 0.524609955884066 PGAP1/ITGB8 2 GO:0007018 microtubule-based movement 6/244 382/18722 0.380175182417398 0.524676879220315 ARMCX3/DST/APP/ATP2B4/IFT27/HTT 6 GO:0032886 regulation of microtubule-based process 4/244 240/18722 0.38174030980937 0.525579959453425 EFNA5/MET/AKAP9/MACF1 4 GO:0007259 receptor signaling pathway via JAK-STAT 3/244 170/18722 0.382083931099536 0.525579959453425 IL6ST/ISL1/OCIAD2 3 GO:0043487 regulation of RNA stability 3/244 170/18722 0.382083931099536 0.525579959453425 TNRC6B/NAF1/PUM1 3 GO:0019932 second-messenger-mediated signaling 5/244 312/18722 0.384266454326579 0.525579959453425 PPP1R9A/CALM1/RCAN1/ATP2B4/HTT 5 GO:0032677 regulation of interleukin-8 production 2/244 102/18722 0.38460192217736 0.525579959453425 MAPKBP1/HYAL2 2 GO:0034308 primary alcohol metabolic process 2/244 102/18722 0.38460192217736 0.525579959453425 ACSS1/RDH14 2 GO:1902106 negative regulation of leukocyte differentiation 2/244 102/18722 0.38460192217736 0.525579959453425 FBN1/GLI3 2 GO:1902749 regulation of cell cycle G2/M phase transition 2/244 102/18722 0.38460192217736 0.525579959453425 APP/PBX1 2 GO:0000154 rRNA modification 1/244 37/18722 0.384828174815868 0.525579959453425 NAF1 1 GO:0001990 regulation of systemic arterial blood pressure by hormone 1/244 37/18722 0.384828174815868 0.525579959453425 ENPEP 1 GO:0007340 acrosome reaction 1/244 37/18722 0.384828174815868 0.525579959453425 SPESP1 1 GO:0014904 myotube cell development 1/244 37/18722 0.384828174815868 0.525579959453425 RCAN1 1 GO:0021532 neural tube patterning 1/244 37/18722 0.384828174815868 0.525579959453425 GLI3 1 GO:0031646 positive regulation of nervous system process 1/244 37/18722 0.384828174815868 0.525579959453425 DAG1 1 GO:0032570 response to progesterone 1/244 37/18722 0.384828174815868 0.525579959453425 CLDN4 1 GO:0033363 secretory granule organization 1/244 37/18722 0.384828174815868 0.525579959453425 SERPINE2 1 GO:0034260 negative regulation of GTPase activity 1/244 37/18722 0.384828174815868 0.525579959453425 AMOT 1 GO:0043368 positive T cell selection 1/244 37/18722 0.384828174815868 0.525579959453425 CTSL 1 GO:0045616 regulation of keratinocyte differentiation 1/244 37/18722 0.384828174815868 0.525579959453425 FOXC1 1 GO:0050775 positive regulation of dendrite morphogenesis 1/244 37/18722 0.384828174815868 0.525579959453425 CUX1 1 GO:0051567 histone H3-K9 methylation 1/244 37/18722 0.384828174815868 0.525579959453425 JARID2 1 GO:0051954 positive regulation of amine transport 1/244 37/18722 0.384828174815868 0.525579959453425 ITGB1 1 GO:0062237 protein localization to postsynapse 1/244 37/18722 0.384828174815868 0.525579959453425 DAG1 1 GO:1900077 negative regulation of cellular response to insulin stimulus 1/244 37/18722 0.384828174815868 0.525579959453425 KANK1 1 GO:1904358 positive regulation of telomere maintenance via telomere lengthening 1/244 37/18722 0.384828174815868 0.525579959453425 NAF1 1 GO:0045786 negative regulation of cell cycle 6/244 385/18722 0.387152308537027 0.528534476881043 NR2F2/LATS2/BMP7/BTG3/FOXC1/CTDSPL 6 GO:0001678 cellular glucose homeostasis 3/244 172/18722 0.389133365786964 0.530387584847074 EFNA5/LRP5/LRP1 3 GO:0032637 interleukin-8 production 2/244 103/18722 0.389221858848568 0.530387584847074 MAPKBP1/HYAL2 2 GO:0032760 positive regulation of tumor necrosis factor production 2/244 103/18722 0.389221858848568 0.530387584847074 ISL1/APP 2 GO:0050773 regulation of dendrite development 2/244 103/18722 0.389221858848568 0.530387584847074 BMP7/CUX1 2 GO:0006605 protein targeting 5/244 314/18722 0.389432270234958 0.530387584847074 TCAF1/HSPA5/HUWE1/LMAN1/SREBF2 5 GO:0045860 positive regulation of protein kinase activity 6/244 386/18722 0.389478162579425 0.530387584847074 EFNA5/PPP1R9A/CALM1/DAG1/ERP29/ATP2B4 6 GO:0010469 regulation of signaling receptor activity 3/244 173/18722 0.392650910695014 0.531470875297125 APP/AKAP9/ITGB1 3 GO:0001825 blastocyst formation 1/244 38/18722 0.392861459554691 0.531470875297125 HOPX 1 GO:0006882 cellular zinc ion homeostasis 1/244 38/18722 0.392861459554691 0.531470875297125 SLC39A10 1 GO:0010613 positive regulation of cardiac muscle hypertrophy 1/244 38/18722 0.392861459554691 0.531470875297125 IL6ST 1 GO:0010742 macrophage derived foam cell differentiation 1/244 38/18722 0.392861459554691 0.531470875297125 ITGAV 1 GO:0032373 positive regulation of sterol transport 1/244 38/18722 0.392861459554691 0.531470875297125 LRP1 1 GO:0032376 positive regulation of cholesterol transport 1/244 38/18722 0.392861459554691 0.531470875297125 LRP1 1 GO:0032717 negative regulation of interleukin-8 production 1/244 38/18722 0.392861459554691 0.531470875297125 MAPKBP1 1 GO:0032941 secretion by tissue 1/244 38/18722 0.392861459554691 0.531470875297125 KCNN4 1 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway 1/244 38/18722 0.392861459554691 0.531470875297125 ISL1 1 GO:0042491 inner ear auditory receptor cell differentiation 1/244 38/18722 0.392861459554691 0.531470875297125 MCOLN3 1 GO:0048713 regulation of oligodendrocyte differentiation 1/244 38/18722 0.392861459554691 0.531470875297125 DAG1 1 GO:0090077 foam cell differentiation 1/244 38/18722 0.392861459554691 0.531470875297125 ITGAV 1 GO:0098926 postsynaptic signal transduction 1/244 38/18722 0.392861459554691 0.531470875297125 GNAQ 1 GO:1903580 positive regulation of ATP metabolic process 1/244 38/18722 0.392861459554691 0.531470875297125 APP 1 GO:2000279 negative regulation of DNA biosynthetic process 1/244 38/18722 0.392861459554691 0.531470875297125 GJA1 1 GO:0006892 post-Golgi vesicle-mediated transport 2/244 104/18722 0.393826452800825 0.532338018882563 MACF1/SPTBN1 2 GO:0022600 digestive system process 2/244 104/18722 0.393826452800825 0.532338018882563 KCNN4/SLC46A1 2 GO:0043414 macromolecule methylation 5/244 316/18722 0.394595527107791 0.533158265656333 MPHOSPH8/JARID2/TARBP1/MLLT6/DNMT3A 5 GO:0001659 temperature homeostasis 3/244 174/18722 0.396163359847882 0.535056638084727 ADRB1/GJA1/LGR4 3 GO:0000041 transition metal ion transport 2/244 105/18722 0.398415319155513 0.537214911261804 SLC39A10/SLC46A1 2 GO:0040029 regulation of gene expression, epigenetic 2/244 105/18722 0.398415319155513 0.537214911261804 MPHOSPH8/DNMT3A 2 GO:0062207 regulation of pattern recognition receptor signaling pathway 2/244 105/18722 0.398415319155513 0.537214911261804 LGR4/PUM1 2 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 2/244 105/18722 0.398415319155513 0.537214911261804 DZIP1/HTT 2 GO:0016570 histone modification 7/244 463/18722 0.399256585016794 0.53812844067481 ISL1/JARID2/PHF20/HUWE1/TBL1X/HOPX/MLLT6 7 GO:0001941 postsynaptic membrane organization 1/244 39/18722 0.400790265156739 0.53908997597423 NLGN4X 1 GO:0014742 positive regulation of muscle hypertrophy 1/244 39/18722 0.400790265156739 0.53908997597423 IL6ST 1 GO:0034314 Arp2/3 complex-mediated actin nucleation 1/244 39/18722 0.400790265156739 0.53908997597423 IQGAP2 1 GO:0045823 positive regulation of heart contraction 1/244 39/18722 0.400790265156739 0.53908997597423 ADRB1 1 GO:2000249 regulation of actin cytoskeleton reorganization 1/244 39/18722 0.400790265156739 0.53908997597423 IQGAP2 1 GO:1901214 regulation of neuron death 5/244 319/18722 0.402333744462542 0.54094463351224 JUN/LRP1/ISL1/DHCR24/LGMN 5 GO:1903707 negative regulation of hemopoiesis 2/244 106/18722 0.402988085580263 0.541381377439389 FBN1/GLI3 2 GO:2000278 regulation of DNA biosynthetic process 2/244 106/18722 0.402988085580263 0.541381377439389 GJA1/NAF1 2 GO:0043405 regulation of MAP kinase activity 3/244 177/18722 0.406667843163639 0.544048620363534 BMP7/ERP29/HYAL2 3 GO:0032526 response to retinoic acid 2/244 107/18722 0.407544392029691 0.544048620363534 SLC6A4/GJA1 2 GO:0051341 regulation of oxidoreductase activity 2/244 107/18722 0.407544392029691 0.544048620363534 CALM1/ATP2B4 2 GO:0071868 cellular response to monoamine stimulus 2/244 107/18722 0.407544392029691 0.544048620363534 APP/ATP2B4 2 GO:0071870 cellular response to catecholamine stimulus 2/244 107/18722 0.407544392029691 0.544048620363534 APP/ATP2B4 2 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 2/244 107/18722 0.407544392029691 0.544048620363534 ISL1/APP 2 GO:0001819 positive regulation of cytokine production 7/244 467/18722 0.407789816538115 0.544048620363534 LRP1/IL6ST/ISL1/APP/GAPDH/SPTBN1/HYAL2 7 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 4/244 249/18722 0.408220238208606 0.544048620363534 MAPKBP1/GAPDH/WLS/GJA1 4 GO:0009069 serine family amino acid metabolic process 1/244 40/18722 0.408615944935241 0.544048620363534 GLDC 1 GO:0032892 positive regulation of organic acid transport 1/244 40/18722 0.408615944935241 0.544048620363534 ITGB1 1 GO:0034122 negative regulation of toll-like receptor signaling pathway 1/244 40/18722 0.408615944935241 0.544048620363534 LGR4 1 GO:0042073 intraciliary transport 1/244 40/18722 0.408615944935241 0.544048620363534 IFT27 1 GO:0045022 early endosome to late endosome transport 1/244 40/18722 0.408615944935241 0.544048620363534 HOOK2 1 GO:0045740 positive regulation of DNA replication 1/244 40/18722 0.408615944935241 0.544048620363534 JUN 1 GO:0055069 zinc ion homeostasis 1/244 40/18722 0.408615944935241 0.544048620363534 SLC39A10 1 GO:0060412 ventricular septum morphogenesis 1/244 40/18722 0.408615944935241 0.544048620363534 TGFBR3 1 GO:0071276 cellular response to cadmium ion 1/244 40/18722 0.408615944935241 0.544048620363534 JUN 1 GO:0072210 metanephric nephron development 1/244 40/18722 0.408615944935241 0.544048620363534 LGR4 1 GO:0097352 autophagosome maturation 1/244 40/18722 0.408615944935241 0.544048620363534 CALM1 1 GO:1901020 negative regulation of calcium ion transmembrane transporter activity 1/244 40/18722 0.408615944935241 0.544048620363534 CALM1 1 GO:1901223 negative regulation of NIK/NF-kappaB signaling 1/244 40/18722 0.408615944935241 0.544048620363534 BMP7 1 GO:2000142 regulation of DNA-templated transcription, initiation 1/244 40/18722 0.408615944935241 0.544048620363534 JUN 1 GO:0009266 response to temperature stimulus 3/244 178/18722 0.410157638498363 0.545659109354502 ADRB1/ATP2B1/SLC52A3 3 GO:0035725 sodium ion transmembrane transport 3/244 178/18722 0.410157638498363 0.545659109354502 UTRN/SLC6A4/ATP2B4 3 GO:0001936 regulation of endothelial cell proliferation 3/244 179/18722 0.413641221424608 0.550070843221879 NR2F2/NRP2/GJA1 3 GO:0001953 negative regulation of cell-matrix adhesion 1/244 41/18722 0.416339834745529 0.550318864430333 LRP1 1 GO:0030488 tRNA methylation 1/244 41/18722 0.416339834745529 0.550318864430333 TARBP1 1 GO:0031062 positive regulation of histone methylation 1/244 41/18722 0.416339834745529 0.550318864430333 JARID2 1 GO:0032735 positive regulation of interleukin-12 production 1/244 41/18722 0.416339834745529 0.550318864430333 ISL1 1 GO:0048286 lung alveolus development 1/244 41/18722 0.416339834745529 0.550318864430333 HOPX 1 GO:0050691 regulation of defense response to virus by host 1/244 41/18722 0.416339834745529 0.550318864430333 RNF216 1 GO:0050856 regulation of T cell receptor signaling pathway 1/244 41/18722 0.416339834745529 0.550318864430333 KCNN4 1 GO:0050892 intestinal absorption 1/244 41/18722 0.416339834745529 0.550318864430333 SLC46A1 1 GO:0055023 positive regulation of cardiac muscle tissue growth 1/244 41/18722 0.416339834745529 0.550318864430333 TGFBR3 1 GO:0060612 adipose tissue development 1/244 41/18722 0.416339834745529 0.550318864430333 LRP5 1 GO:0070296 sarcoplasmic reticulum calcium ion transport 1/244 41/18722 0.416339834745529 0.550318864430333 CALM1 1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 1/244 41/18722 0.416339834745529 0.550318864430333 P4HB 1 GO:1902622 regulation of neutrophil migration 1/244 41/18722 0.416339834745529 0.550318864430333 DPP4 1 GO:1903524 positive regulation of blood circulation 1/244 41/18722 0.416339834745529 0.550318864430333 ADRB1 1 GO:1905314 semi-lunar valve development 1/244 41/18722 0.416339834745529 0.550318864430333 GJA5 1 GO:0045017 glycerolipid biosynthetic process 4/244 252/18722 0.417001743785124 0.550972147196589 CDS1/PGAP1/SACM1L/PIP5K1B 4 GO:0008654 phospholipid biosynthetic process 4/244 253/18722 0.41992265106823 0.554173477523989 CDS1/PGAP1/SACM1L/PIP5K1B 4 GO:0097696 receptor signaling pathway via STAT 3/244 181/18722 0.420588905112059 0.554173477523989 IL6ST/ISL1/OCIAD2 3 GO:1905952 regulation of lipid localization 3/244 181/18722 0.420588905112059 0.554173477523989 LRP1/ITGAV/SREBF2 3 GO:0006939 smooth muscle contraction 2/244 110/18722 0.421111130060074 0.554173477523989 ATP2B1/ATP2B4 2 GO:0007088 regulation of mitotic nuclear division 2/244 110/18722 0.421111130060074 0.554173477523989 LRP5/BMP7 2 GO:0009063 cellular amino acid catabolic process 2/244 110/18722 0.421111130060074 0.554173477523989 ATP2B4/GLDC 2 GO:0032611 interleukin-1 beta production 2/244 110/18722 0.421111130060074 0.554173477523989 ISL1/APP 2 GO:0032651 regulation of interleukin-1 beta production 2/244 110/18722 0.421111130060074 0.554173477523989 ISL1/APP 2 GO:0048259 regulation of receptor-mediated endocytosis 2/244 110/18722 0.421111130060074 0.554173477523989 ITGAV/AAK1 2 GO:1905954 positive regulation of lipid localization 2/244 110/18722 0.421111130060074 0.554173477523989 LRP1/SREBF2 2 GO:0006040 amino sugar metabolic process 1/244 42/18722 0.423963253209321 0.554816109138124 EXTL2 1 GO:0010939 regulation of necrotic cell death 1/244 42/18722 0.423963253209321 0.554816109138124 ASAH1 1 GO:0016601 Rac protein signal transduction 1/244 42/18722 0.423963253209321 0.554816109138124 HACD3 1 GO:0021879 forebrain neuron differentiation 1/244 42/18722 0.423963253209321 0.554816109138124 NRP2 1 GO:0030890 positive regulation of B cell proliferation 1/244 42/18722 0.423963253209321 0.554816109138124 SLC39A10 1 GO:0032467 positive regulation of cytokinesis 1/244 42/18722 0.423963253209321 0.554816109138124 SVIL 1 GO:0042168 heme metabolic process 1/244 42/18722 0.423963253209321 0.554816109138124 SLC46A1 1 GO:0045047 protein targeting to ER 1/244 42/18722 0.423963253209321 0.554816109138124 HSPA5 1 GO:0046596 regulation of viral entry into host cell 1/244 42/18722 0.423963253209321 0.554816109138124 P4HB 1 GO:0051602 response to electrical stimulus 1/244 42/18722 0.423963253209321 0.554816109138124 AKAP9 1 GO:0060999 positive regulation of dendritic spine development 1/244 42/18722 0.423963253209321 0.554816109138124 PPP1R9A 1 GO:0071312 cellular response to alkaloid 1/244 42/18722 0.423963253209321 0.554816109138124 SLC1A3 1 GO:2000404 regulation of T cell migration 1/244 42/18722 0.423963253209321 0.554816109138124 APP 1 GO:2001222 regulation of neuron migration 1/244 42/18722 0.423963253209321 0.554816109138124 SEMA6A 1 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 2/244 111/18722 0.425598233074259 0.556291087463013 PIP5K1B/SERPINE2 2 GO:0071867 response to monoamine 2/244 111/18722 0.425598233074259 0.556291087463013 APP/ATP2B4 2 GO:0071869 response to catecholamine 2/244 111/18722 0.425598233074259 0.556291087463013 APP/ATP2B4 2 GO:0000956 nuclear-transcribed mRNA catabolic process 2/244 112/18722 0.430067251433246 0.560530969868512 TNRC6B/DDX5 2 GO:0035601 protein deacylation 2/244 112/18722 0.430067251433246 0.560530969868512 TBL1X/HOPX 2 GO:0046632 alpha-beta T cell differentiation 2/244 112/18722 0.430067251433246 0.560530969868512 CTSL/GLI3 2 GO:1901222 regulation of NIK/NF-kappaB signaling 2/244 112/18722 0.430067251433246 0.560530969868512 BMP7/APP 2 GO:0001709 cell fate determination 1/244 43/18722 0.431487501936137 0.560530969868512 ISL1 1 GO:0006509 membrane protein ectodomain proteolysis 1/244 43/18722 0.431487501936137 0.560530969868512 DAG1 1 GO:0016266 O-glycan processing 1/244 43/18722 0.431487501936137 0.560530969868512 GALNT11 1 GO:0031952 regulation of protein autophosphorylation 1/244 43/18722 0.431487501936137 0.560530969868512 CALM1 1 GO:0032365 intracellular lipid transport 1/244 43/18722 0.431487501936137 0.560530969868512 PLEKHA8 1 GO:0034661 ncRNA catabolic process 1/244 43/18722 0.431487501936137 0.560530969868512 KCNQ1OT1 1 GO:0045840 positive regulation of mitotic nuclear division 1/244 43/18722 0.431487501936137 0.560530969868512 LRP5 1 GO:0045981 positive regulation of nucleotide metabolic process 1/244 43/18722 0.431487501936137 0.560530969868512 APP 1 GO:0046636 negative regulation of alpha-beta T cell activation 1/244 43/18722 0.431487501936137 0.560530969868512 GLI3 1 GO:0098927 vesicle-mediated transport between endosomal compartments 1/244 43/18722 0.431487501936137 0.560530969868512 HOOK2 1 GO:1900544 positive regulation of purine nucleotide metabolic process 1/244 43/18722 0.431487501936137 0.560530969868512 APP 1 GO:0005996 monosaccharide metabolic process 4/244 257/18722 0.431571318857984 0.560530969868512 LRP5/GAPDH/MAN2A2/FUT8 4 GO:0071214 cellular response to abiotic stimulus 5/244 331/18722 0.433154010373383 0.562142210934809 DAG1/TMEM150C/HSPA5/GJA1/HYAL2 5 GO:0104004 cellular response to environmental stimulus 5/244 331/18722 0.433154010373383 0.562142210934809 DAG1/TMEM150C/HSPA5/GJA1/HYAL2 5 GO:0031623 receptor internalization 2/244 113/18722 0.434517893620387 0.56368961643766 LRP1/ITGB1 2 GO:0045927 positive regulation of growth 4/244 259/18722 0.437372812385814 0.566531540242977 LRP1/MACF1/TGFBR3/HOPX 4 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 3/244 186/18722 0.43783499397288 0.566531540242977 GAPDH/WLS/GJA1 3 GO:0002066 columnar/cuboidal epithelial cell development 1/244 44/18722 0.438913865741886 0.566531540242977 IL6ST 1 GO:0006378 mRNA polyadenylation 1/244 44/18722 0.438913865741886 0.566531540242977 APP 1 GO:0030521 androgen receptor signaling pathway 1/244 44/18722 0.438913865741886 0.566531540242977 DDX5 1 GO:0031295 T cell costimulation 1/244 44/18722 0.438913865741886 0.566531540242977 DPP4 1 GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT 1/244 44/18722 0.438913865741886 0.566531540242977 OCIAD2 1 GO:0060324 face development 1/244 44/18722 0.438913865741886 0.566531540242977 ANKRD11 1 GO:0062208 positive regulation of pattern recognition receptor signaling pathway 1/244 44/18722 0.438913865741886 0.566531540242977 PUM1 1 GO:0150076 neuroinflammatory response 1/244 44/18722 0.438913865741886 0.566531540242977 ITGB1 1 GO:0007041 lysosomal transport 2/244 114/18722 0.438949878715344 0.566531540242977 LRP1/HOOK2 2 GO:0051261 protein depolymerization 2/244 114/18722 0.438949878715344 0.566531540242977 SVIL/SPTBN1 2 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2/244 114/18722 0.438949878715344 0.566531540242977 BMP7/TGFBR3 2 GO:0061136 regulation of proteasomal protein catabolic process 3/244 187/18722 0.441261546085685 0.569291496049298 TMTC3/USP25/SVIP 3 GO:0034968 histone lysine methylation 2/244 115/18722 0.443362936169438 0.571553789036003 JARID2/MLLT6 2 GO:0042471 ear morphogenesis 2/244 115/18722 0.443362936169438 0.571553789036003 NAGLU/ATP6V1B1 2 GO:0003254 regulation of membrane depolarization 1/244 45/18722 0.44624361286465 0.572348365290101 GJA5 1 GO:0006110 regulation of glycolytic process 1/244 45/18722 0.44624361286465 0.572348365290101 APP 1 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 1/244 45/18722 0.44624361286465 0.572348365290101 P4HB 1 GO:0035384 thioester biosynthetic process 1/244 45/18722 0.44624361286465 0.572348365290101 ACSS1 1 GO:0042551 neuron maturation 1/244 45/18722 0.44624361286465 0.572348365290101 APP 1 GO:0043631 RNA polyadenylation 1/244 45/18722 0.44624361286465 0.572348365290101 APP 1 GO:0048546 digestive tract morphogenesis 1/244 45/18722 0.44624361286465 0.572348365290101 GLI3 1 GO:0060421 positive regulation of heart growth 1/244 45/18722 0.44624361286465 0.572348365290101 TGFBR3 1 GO:0071354 cellular response to interleukin-6 1/244 45/18722 0.44624361286465 0.572348365290101 IL6ST 1 GO:0071364 cellular response to epidermal growth factor stimulus 1/244 45/18722 0.44624361286465 0.572348365290101 FOXC1 1 GO:0071616 acyl-CoA biosynthetic process 1/244 45/18722 0.44624361286465 0.572348365290101 ACSS1 1 GO:1901985 positive regulation of protein acetylation 1/244 45/18722 0.44624361286465 0.572348365290101 ISL1 1 GO:2000273 positive regulation of signaling receptor activity 1/244 45/18722 0.44624361286465 0.572348365290101 ITGB1 1 GO:0030518 intracellular steroid hormone receptor signaling pathway 2/244 116/18722 0.447756805585027 0.573393945110054 ISL1/DDX5 2 GO:0043200 response to amino acid 2/244 116/18722 0.447756805585027 0.573393945110054 SLC38A9/DNMT3A 2 GO:0098732 macromolecule deacylation 2/244 116/18722 0.447756805585027 0.573393945110054 TBL1X/HOPX 2 GO:1990748 cellular detoxification 2/244 116/18722 0.447756805585027 0.573393945110054 BMP7/SOD3 2 GO:0046578 regulation of Ras protein signal transduction 3/244 189/18722 0.448090496364142 0.57359772927642 KANK1/MET/ITGB1 3 GO:0060271 cilium assembly 5/244 337/18722 0.448447362920212 0.573831010341051 GALNT11/DZIP1/LAMA5/UNC119B/HTT 5 GO:0009566 fertilization 3/244 190/18722 0.451492538192895 0.57750271720586 NR2F2/FOLR1/SPESP1 3 GO:0072676 lymphocyte migration 2/244 117/18722 0.45213123649883 0.57762638860011 APP/MIA3 2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 1/244 46/18722 0.453477995177709 0.57762638860011 TENM3 1 GO:0031294 lymphocyte costimulation 1/244 46/18722 0.453477995177709 0.57762638860011 DPP4 1 GO:0031648 protein destabilization 1/244 46/18722 0.453477995177709 0.57762638860011 HTT 1 GO:0045851 pH reduction 1/244 46/18722 0.453477995177709 0.57762638860011 ATP6V1B1 1 GO:0048701 embryonic cranial skeleton morphogenesis 1/244 46/18722 0.453477995177709 0.57762638860011 GLI3 1 GO:0061028 establishment of endothelial barrier 1/244 46/18722 0.453477995177709 0.57762638860011 VCL 1 GO:0072599 establishment of protein localization to endoplasmic reticulum 1/244 46/18722 0.453477995177709 0.57762638860011 HSPA5 1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 1/244 46/18722 0.453477995177709 0.57762638860011 ADAMTS1 1 GO:2000107 negative regulation of leukocyte apoptotic process 1/244 46/18722 0.453477995177709 0.57762638860011 SLC39A10 1 GO:0006790 sulfur compound metabolic process 5/244 339/18722 0.453522849235631 0.57762638860011 SLC26A2/SLC19A3/GNS/ACSS1/MTR 5 GO:1903313 positive regulation of mRNA metabolic process 2/244 118/18722 0.456485988169131 0.581157595611996 TNRC6B/PUM1 2 GO:0006091 generation of precursor metabolites and energy 7/244 490/18722 0.456649090648257 0.581157595611996 IL6ST/APP/PDIA5/LDHA/GAPDH/ACSS1/GLDC 7 GO:0001774 microglial cell activation 1/244 47/18722 0.460618248399847 0.582150601631499 APP 1 GO:0016574 histone ubiquitination 1/244 47/18722 0.460618248399847 0.582150601631499 HUWE1 1 GO:0031641 regulation of myelination 1/244 47/18722 0.460618248399847 0.582150601631499 DAG1 1 GO:0032008 positive regulation of TOR signaling 1/244 47/18722 0.460618248399847 0.582150601631499 SLC38A9 1 GO:0035315 hair cell differentiation 1/244 47/18722 0.460618248399847 0.582150601631499 MCOLN3 1 GO:0045332 phospholipid translocation 1/244 47/18722 0.460618248399847 0.582150601631499 KCNN4 1 GO:0045581 negative regulation of T cell differentiation 1/244 47/18722 0.460618248399847 0.582150601631499 GLI3 1 GO:0045601 regulation of endothelial cell differentiation 1/244 47/18722 0.460618248399847 0.582150601631499 VCL 1 GO:0047496 vesicle transport along microtubule 1/244 47/18722 0.460618248399847 0.582150601631499 HTT 1 GO:0048483 autonomic nervous system development 1/244 47/18722 0.460618248399847 0.582150601631499 NRP2 1 GO:0051489 regulation of filopodium assembly 1/244 47/18722 0.460618248399847 0.582150601631499 PPP1R9A 1 GO:0051972 regulation of telomerase activity 1/244 47/18722 0.460618248399847 0.582150601631499 NAF1 1 GO:0061001 regulation of dendritic spine morphogenesis 1/244 47/18722 0.460618248399847 0.582150601631499 PPP1R9A 1 GO:0072583 clathrin-dependent endocytosis 1/244 47/18722 0.460618248399847 0.582150601631499 AAK1 1 GO:0097028 dendritic cell differentiation 1/244 47/18722 0.460618248399847 0.582150601631499 ITGB8 1 GO:0097300 programmed necrotic cell death 1/244 47/18722 0.460618248399847 0.582150601631499 ASAH1 1 GO:0120163 negative regulation of cold-induced thermogenesis 1/244 47/18722 0.460618248399847 0.582150601631499 LGR4 1 GO:1903170 negative regulation of calcium ion transmembrane transport 1/244 47/18722 0.460618248399847 0.582150601631499 CALM1 1 GO:0031398 positive regulation of protein ubiquitination 2/244 119/18722 0.460820829366808 0.582182716378059 HSPA5/HUWE1 2 GO:0001935 endothelial cell proliferation 3/244 193/18722 0.46164686455089 0.582778177838733 NR2F2/NRP2/GJA1 3 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 3/244 193/18722 0.46164686455089 0.582778177838733 EFNA5/IL6ST/ISL1 3 GO:0002761 regulation of myeloid leukocyte differentiation 2/244 120/18722 0.465135538170125 0.586506284891416 FBN1/JUN 2 GO:0006304 DNA modification 2/244 120/18722 0.465135538170125 0.586506284891416 MPHOSPH8/DNMT3A 2 GO:0071774 response to fibroblast growth factor 2/244 120/18722 0.465135538170125 0.586506284891416 IER2/HYAL2 2 GO:0002673 regulation of acute inflammatory response 1/244 48/18722 0.46766559230295 0.587666973731355 IL6ST 1 GO:0015804 neutral amino acid transport 1/244 48/18722 0.46766559230295 0.587666973731355 SLC38A9 1 GO:0032527 protein exit from endoplasmic reticulum 1/244 48/18722 0.46766559230295 0.587666973731355 SVIP 1 GO:0033628 regulation of cell adhesion mediated by integrin 1/244 48/18722 0.46766559230295 0.587666973731355 DPP4 1 GO:0042908 xenobiotic transport 1/244 48/18722 0.46766559230295 0.587666973731355 GJA1 1 GO:0045839 negative regulation of mitotic nuclear division 1/244 48/18722 0.46766559230295 0.587666973731355 BMP7 1 GO:0061647 histone H3-K9 modification 1/244 48/18722 0.46766559230295 0.587666973731355 JARID2 1 GO:0120009 intermembrane lipid transfer 1/244 48/18722 0.46766559230295 0.587666973731355 PLEKHA8 1 GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 1/244 48/18722 0.46766559230295 0.587666973731355 SVIP 1 GO:1901605 alpha-amino acid metabolic process 3/244 195/18722 0.46837159569008 0.588329152690215 ATP2B4/GLDC/MTR 3 GO:0038127 ERBB signaling pathway 2/244 121/18722 0.46942990176321 0.588983068802561 EFEMP1/LGMN 2 GO:0042752 regulation of circadian rhythm 2/244 121/18722 0.46942990176321 0.588983068802561 ADRB1/GNAQ 2 GO:0043244 regulation of protein-containing complex disassembly 2/244 121/18722 0.46942990176321 0.588983068802561 SVIL/SPTBN1 2 GO:0071674 mononuclear cell migration 3/244 196/18722 0.471720036710199 0.590312401511408 APP/MIA3/LGMN 3 GO:0002688 regulation of leukocyte chemotaxis 2/244 122/18722 0.473703716238174 0.590312401511408 DPP4/LGMN 2 GO:0031109 microtubule polymerization or depolymerization 2/244 122/18722 0.473703716238174 0.590312401511408 MET/AKAP9 2 GO:0002762 negative regulation of myeloid leukocyte differentiation 1/244 49/18722 0.474621230916963 0.590312401511408 FBN1 1 GO:0006376 mRNA splice site selection 1/244 49/18722 0.474621230916963 0.590312401511408 SF1 1 GO:0006692 prostanoid metabolic process 1/244 49/18722 0.474621230916963 0.590312401511408 ATP6V1B1 1 GO:0006693 prostaglandin metabolic process 1/244 49/18722 0.474621230916963 0.590312401511408 ATP6V1B1 1 GO:0006778 porphyrin-containing compound metabolic process 1/244 49/18722 0.474621230916963 0.590312401511408 SLC46A1 1 GO:0008206 bile acid metabolic process 1/244 49/18722 0.474621230916963 0.590312401511408 SLC27A2 1 GO:0009066 aspartate family amino acid metabolic process 1/244 49/18722 0.474621230916963 0.590312401511408 MTR 1 GO:0009994 oocyte differentiation 1/244 49/18722 0.474621230916963 0.590312401511408 LGR5 1 GO:0010823 negative regulation of mitochondrion organization 1/244 49/18722 0.474621230916963 0.590312401511408 HUWE1 1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 1/244 49/18722 0.474621230916963 0.590312401511408 BMP7 1 GO:0030195 negative regulation of blood coagulation 1/244 49/18722 0.474621230916963 0.590312401511408 SERPINE2 1 GO:0030225 macrophage differentiation 1/244 49/18722 0.474621230916963 0.590312401511408 APP 1 GO:0048168 regulation of neuronal synaptic plasticity 1/244 49/18722 0.474621230916963 0.590312401511408 APP 1 GO:0050832 defense response to fungus 1/244 49/18722 0.474621230916963 0.590312401511408 GAPDH 1 GO:0051932 synaptic transmission, GABAergic 1/244 49/18722 0.474621230916963 0.590312401511408 GABRE 1 GO:0070741 response to interleukin-6 1/244 49/18722 0.474621230916963 0.590312401511408 IL6ST 1 GO:0070849 response to epidermal growth factor 1/244 49/18722 0.474621230916963 0.590312401511408 FOXC1 1 GO:0072091 regulation of stem cell proliferation 1/244 49/18722 0.474621230916963 0.590312401511408 GJA1 1 GO:1904894 positive regulation of receptor signaling pathway via STAT 1/244 49/18722 0.474621230916963 0.590312401511408 OCIAD2 1 GO:1990573 potassium ion import across plasma membrane 1/244 49/18722 0.474621230916963 0.590312401511408 SLC12A9 1 GO:0019083 viral transcription 1/244 50/18722 0.481486352732218 0.596569046949458 JUN 1 GO:0042572 retinol metabolic process 1/244 50/18722 0.481486352732218 0.596569046949458 RDH14 1 GO:0046638 positive regulation of alpha-beta T cell differentiation 1/244 50/18722 0.481486352732218 0.596569046949458 GLI3 1 GO:0051646 mitochondrion localization 1/244 50/18722 0.481486352732218 0.596569046949458 ARMCX3 1 GO:0060425 lung morphogenesis 1/244 50/18722 0.481486352732218 0.596569046949458 DAG1 1 GO:0070231 T cell apoptotic process 1/244 50/18722 0.481486352732218 0.596569046949458 GLI3 1 GO:0090102 cochlea development 1/244 50/18722 0.481486352732218 0.596569046949458 IFT27 1 GO:1900047 negative regulation of hemostasis 1/244 50/18722 0.481486352732218 0.596569046949458 SERPINE2 1 GO:1902930 regulation of alcohol biosynthetic process 1/244 50/18722 0.481486352732218 0.596569046949458 P2RY6 1 GO:2000677 regulation of transcription regulatory region DNA binding 1/244 50/18722 0.481486352732218 0.596569046949458 FOXC1 1 GO:1903131 mononuclear cell differentiation 6/244 426/18722 0.481648716237648 0.596569046949458 JUN/CTSL/ITGB1/PBX1/ITGB8/GLI3 6 GO:0007368 determination of left/right symmetry 2/244 124/18722 0.482188925579804 0.596788252148864 GALNT11/FOLR1 2 GO:0010508 positive regulation of autophagy 2/244 124/18722 0.482188925579804 0.596788252148864 HTT/SVIP 2 GO:0071902 positive regulation of protein serine/threonine kinase activity 3/244 200/18722 0.485017439080374 0.600062991271878 CALM1/ERP29/ATP2B4 3 GO:0055007 cardiac muscle cell differentiation 2/244 125/18722 0.486399955439395 0.601546952794073 ISL1/ITGB1 2 GO:0009584 detection of visible light 1/244 51/18722 0.488262130899171 0.602037284103068 GNAQ 1 GO:0010656 negative regulation of muscle cell apoptotic process 1/244 51/18722 0.488262130899171 0.602037284103068 BMP7 1 GO:0032964 collagen biosynthetic process 1/244 51/18722 0.488262130899171 0.602037284103068 SERPINH1 1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 1/244 51/18722 0.488262130899171 0.602037284103068 MAPKBP1 1 GO:0045668 negative regulation of osteoblast differentiation 1/244 51/18722 0.488262130899171 0.602037284103068 LRP5 1 GO:0050982 detection of mechanical stimulus 1/244 51/18722 0.488262130899171 0.602037284103068 SERPINE2 1 GO:0065002 intracellular protein transmembrane transport 1/244 51/18722 0.488262130899171 0.602037284103068 HSPA5 1 GO:0071622 regulation of granulocyte chemotaxis 1/244 51/18722 0.488262130899171 0.602037284103068 DPP4 1 GO:0046034 ATP metabolic process 4/244 277/18722 0.488723574859699 0.602380220175909 APP/LDHA/ATP6V1B1/GAPDH 4 GO:2001235 positive regulation of apoptotic signaling pathway 2/244 126/18722 0.490589705795462 0.604453608265425 PDIA3/HYAL2 2 GO:0031349 positive regulation of defense response 4/244 278/18722 0.491523321140173 0.605376924012971 IL6ST/APP/GJA1/HYAL2 4 GO:0010662 regulation of striated muscle cell apoptotic process 1/244 52/18722 0.494949723425581 0.608456712000171 BMP7 1 GO:0032206 positive regulation of telomere maintenance 1/244 52/18722 0.494949723425581 0.608456712000171 NAF1 1 GO:0034204 lipid translocation 1/244 52/18722 0.494949723425581 0.608456712000171 KCNN4 1 GO:0043392 negative regulation of DNA binding 1/244 52/18722 0.494949723425581 0.608456712000171 JUN 1 GO:0045010 actin nucleation 1/244 52/18722 0.494949723425581 0.608456712000171 IQGAP2 1 GO:0001818 negative regulation of cytokine production 5/244 357/18722 0.498566971835411 0.611945103665487 ATP2B1/MAPKBP1/RNF216/LGR4/TSKU 5 GO:0032612 interleukin-1 production 2/244 128/18722 0.498904726938478 0.611945103665487 ISL1/APP 2 GO:0032652 regulation of interleukin-1 production 2/244 128/18722 0.498904726938478 0.611945103665487 ISL1/APP 2 GO:0033865 nucleoside bisphosphate metabolic process 2/244 128/18722 0.498904726938478 0.611945103665487 SLC26A2/ACSS1 2 GO:0033875 ribonucleoside bisphosphate metabolic process 2/244 128/18722 0.498904726938478 0.611945103665487 SLC26A2/ACSS1 2 GO:0034032 purine nucleoside bisphosphate metabolic process 2/244 128/18722 0.498904726938478 0.611945103665487 SLC26A2/ACSS1 2 GO:0001541 ovarian follicle development 1/244 53/18722 0.50155027337117 0.613815343872501 FOXC1 1 GO:0032210 regulation of telomere maintenance via telomerase 1/244 53/18722 0.50155027337117 0.613815343872501 NAF1 1 GO:0034381 plasma lipoprotein particle clearance 1/244 53/18722 0.50155027337117 0.613815343872501 NCEH1 1 GO:0045806 negative regulation of endocytosis 1/244 53/18722 0.50155027337117 0.613815343872501 ITGAV 1 GO:0050819 negative regulation of coagulation 1/244 53/18722 0.50155027337117 0.613815343872501 SERPINE2 1 GO:1903202 negative regulation of oxidative stress-induced cell death 1/244 53/18722 0.50155027337117 0.613815343872501 MET 1 GO:0050679 positive regulation of epithelial cell proliferation 3/244 207/18722 0.507895308592256 0.619629198191315 LAMC1/NRP2/LAMB1 3 GO:0014888 striated muscle adaptation 1/244 54/18722 0.508064909039788 0.619629198191315 ATP2B4 1 GO:0035065 regulation of histone acetylation 1/244 54/18722 0.508064909039788 0.619629198191315 ISL1 1 GO:0043647 inositol phosphate metabolic process 1/244 54/18722 0.508064909039788 0.619629198191315 P2RY6 1 GO:0070228 regulation of lymphocyte apoptotic process 1/244 54/18722 0.508064909039788 0.619629198191315 SLC39A10 1 GO:0072698 protein localization to microtubule cytoskeleton 1/244 54/18722 0.508064909039788 0.619629198191315 GOLGB1 1 GO:1902743 regulation of lamellipodium organization 1/244 54/18722 0.508064909039788 0.619629198191315 KANK1 1 GO:2000300 regulation of synaptic vesicle exocytosis 1/244 54/18722 0.508064909039788 0.619629198191315 CALM1 1 GO:0006520 cellular amino acid metabolic process 4/244 284/18722 0.508186454390016 0.619629198191315 ATP2B4/GLDC/MTR/SLC1A3 4 GO:0015850 organic hydroxy compound transport 4/244 284/18722 0.508186454390016 0.619629198191315 LRP1/SLC6A4/SREBF2/TSKU 4 GO:1901215 negative regulation of neuron death 3/244 208/18722 0.511120705288316 0.622396714768936 LRP1/ISL1/LGMN 3 GO:0006612 protein targeting to membrane 2/244 131/18722 0.511213856713743 0.622396714768936 TCAF1/HSPA5 2 GO:0018022 peptidyl-lysine methylation 2/244 131/18722 0.511213856713743 0.622396714768936 JARID2/MLLT6 2 GO:0019827 stem cell population maintenance 2/244 131/18722 0.511213856713743 0.622396714768936 LRP5/BMP7 2 GO:0003179 heart valve morphogenesis 1/244 55/18722 0.514494744169116 0.625232888069422 GJA5 1 GO:0006414 translational elongation 1/244 55/18722 0.514494744169116 0.625232888069422 NEMF 1 GO:0008333 endosome to lysosome transport 1/244 55/18722 0.514494744169116 0.625232888069422 HOOK2 1 GO:0010676 positive regulation of cellular carbohydrate metabolic process 1/244 55/18722 0.514494744169116 0.625232888069422 P2RY6 1 GO:0045620 negative regulation of lymphocyte differentiation 1/244 55/18722 0.514494744169116 0.625232888069422 GLI3 1 GO:0009855 determination of bilateral symmetry 2/244 133/18722 0.519309466638175 0.629684740800426 GALNT11/FOLR1 2 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1/244 56/18722 0.520840878117942 0.629684740800426 TNRC6B 1 GO:0006687 glycosphingolipid metabolic process 1/244 56/18722 0.520840878117942 0.629684740800426 ITGB8 1 GO:0010332 response to gamma radiation 1/244 56/18722 0.520840878117942 0.629684740800426 HSPA5 1 GO:0010658 striated muscle cell apoptotic process 1/244 56/18722 0.520840878117942 0.629684740800426 BMP7 1 GO:0030166 proteoglycan biosynthetic process 1/244 56/18722 0.520840878117942 0.629684740800426 EXTL2 1 GO:0032608 interferon-beta production 1/244 56/18722 0.520840878117942 0.629684740800426 RNF216 1 GO:0032648 regulation of interferon-beta production 1/244 56/18722 0.520840878117942 0.629684740800426 RNF216 1 GO:0043470 regulation of carbohydrate catabolic process 1/244 56/18722 0.520840878117942 0.629684740800426 APP 1 GO:0045071 negative regulation of viral genome replication 1/244 56/18722 0.520840878117942 0.629684740800426 MPHOSPH8 1 GO:0045599 negative regulation of fat cell differentiation 1/244 56/18722 0.520840878117942 0.629684740800426 ANKRD26 1 GO:0046622 positive regulation of organ growth 1/244 56/18722 0.520840878117942 0.629684740800426 TGFBR3 1 GO:0048008 platelet-derived growth factor receptor signaling pathway 1/244 56/18722 0.520840878117942 0.629684740800426 LRP1 1 GO:0051784 negative regulation of nuclear division 1/244 56/18722 0.520840878117942 0.629684740800426 BMP7 1 GO:0008277 regulation of G protein-coupled receptor signaling pathway 2/244 134/18722 0.523323774435965 0.631756768110427 MET/ATP2B4 2 GO:0009799 specification of symmetry 2/244 134/18722 0.523323774435965 0.631756768110427 GALNT11/FOLR1 2 GO:0042552 myelination 2/244 134/18722 0.523323774435965 0.631756768110427 ITGB4/DAG1 2 GO:0098727 maintenance of cell number 2/244 134/18722 0.523323774435965 0.631756768110427 LRP5/BMP7 2 GO:0030258 lipid modification 3/244 212/18722 0.523910389598032 0.632232662585065 SACM1L/SLC27A2/PLPP3 3 GO:0009150 purine ribonucleotide metabolic process 5/244 368/18722 0.525403102215642 0.633801245917988 SLC26A2/APP/LDHA/GAPDH/ACSS1 5 GO:0006695 cholesterol biosynthetic process 1/244 57/18722 0.527104396051041 0.634223744204951 DHCR24 1 GO:0033619 membrane protein proteolysis 1/244 57/18722 0.527104396051041 0.634223744204951 DAG1 1 GO:0051155 positive regulation of striated muscle cell differentiation 1/244 57/18722 0.527104396051041 0.634223744204951 HOPX 1 GO:0051785 positive regulation of nuclear division 1/244 57/18722 0.527104396051041 0.634223744204951 LRP5 1 GO:0061756 leukocyte adhesion to vascular endothelial cell 1/244 57/18722 0.527104396051041 0.634223744204951 ITGB1 1 GO:0097120 receptor localization to synapse 1/244 57/18722 0.527104396051041 0.634223744204951 DAG1 1 GO:1902653 secondary alcohol biosynthetic process 1/244 57/18722 0.527104396051041 0.634223744204951 DHCR24 1 GO:0050900 leukocyte migration 5/244 369/18722 0.527812521150134 0.634843317898733 APP/ITGB1/MIA3/DPP4/LGMN 5 GO:0044242 cellular lipid catabolic process 3/244 214/18722 0.530236577576225 0.637292389873985 LRP1/SLC27A2/ASAH1 3 GO:0072330 monocarboxylic acid biosynthetic process 3/244 214/18722 0.530236577576225 0.637292389873985 HACD3/SLC27A2/ACSS1 3 GO:0007272 ensheathment of neurons 2/244 136/18722 0.531284872739152 0.637460534352075 ITGB4/DAG1 2 GO:0008366 axon ensheathment 2/244 136/18722 0.531284872739152 0.637460534352075 ITGB4/DAG1 2 GO:0043624 cellular protein complex disassembly 2/244 136/18722 0.531284872739152 0.637460534352075 SVIL/SPTBN1 2 GO:0098876 vesicle-mediated transport to the plasma membrane 2/244 136/18722 0.531284872739152 0.637460534352075 MACF1/SPTBN1 2 GO:0002763 positive regulation of myeloid leukocyte differentiation 1/244 58/18722 0.533286369121684 0.637460534352075 JUN 1 GO:0006826 iron ion transport 1/244 58/18722 0.533286369121684 0.637460534352075 SLC46A1 1 GO:0007405 neuroblast proliferation 1/244 58/18722 0.533286369121684 0.637460534352075 GLI3 1 GO:0010559 regulation of glycoprotein biosynthetic process 1/244 58/18722 0.533286369121684 0.637460534352075 ITM2B 1 GO:0032481 positive regulation of type I interferon production 1/244 58/18722 0.533286369121684 0.637460534352075 GAPDH 1 GO:0043525 positive regulation of neuron apoptotic process 1/244 58/18722 0.533286369121684 0.637460534352075 JUN 1 GO:0044380 protein localization to cytoskeleton 1/244 58/18722 0.533286369121684 0.637460534352075 GOLGB1 1 GO:0045604 regulation of epidermal cell differentiation 1/244 58/18722 0.533286369121684 0.637460534352075 FOXC1 1 GO:0097035 regulation of membrane lipid distribution 1/244 58/18722 0.533286369121684 0.637460534352075 KCNN4 1 GO:1902808 positive regulation of cell cycle G1/S phase transition 1/244 58/18722 0.533286369121684 0.637460534352075 ADAMTS1 1 GO:2000649 regulation of sodium ion transmembrane transporter activity 1/244 58/18722 0.533286369121684 0.637460534352075 UTRN 1 GO:0045862 positive regulation of proteolysis 5/244 372/18722 0.535008640645018 0.638856019505906 APP/CLDN4/PCOLCE2/LGMN/TMTC3 5 GO:0007586 digestion 2/244 137/18722 0.535231473432671 0.638856019505906 KCNN4/SLC46A1 2 GO:0030879 mammary gland development 2/244 137/18722 0.535231473432671 0.638856019505906 LRP5/GLI3 2 GO:0050671 positive regulation of lymphocyte proliferation 2/244 137/18722 0.535231473432671 0.638856019505906 IL6ST/SLC39A10 2 GO:0050870 positive regulation of T cell activation 3/244 216/18722 0.536515910641281 0.640156602166757 IL6ST/DPP4/GLI3 3 GO:0032946 positive regulation of mononuclear cell proliferation 2/244 138/18722 0.539155325694697 0.641719221718267 IL6ST/SLC39A10 2 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 2/244 138/18722 0.539155325694697 0.641719221718267 HSPA5/HUWE1 2 GO:0001836 release of cytochrome c from mitochondria 1/244 59/18722 0.539387854651812 0.641719221718267 JUN 1 GO:0048010 vascular endothelial growth factor receptor signaling pathway 1/244 59/18722 0.539387854651812 0.641719221718267 FOXC1 1 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 1/244 59/18722 0.539387854651812 0.641719221718267 HYAL2 1 GO:0051353 positive regulation of oxidoreductase activity 1/244 59/18722 0.539387854651812 0.641719221718267 CALM1 1 GO:0071806 protein transmembrane transport 1/244 59/18722 0.539387854651812 0.641719221718267 HSPA5 1 GO:2001258 negative regulation of cation channel activity 1/244 59/18722 0.539387854651812 0.641719221718267 CALM1 1 GO:0051783 regulation of nuclear division 2/244 139/18722 0.543056350023855 0.645849861085193 LRP5/BMP7 2 GO:0044282 small molecule catabolic process 5/244 376/18722 0.544526255773263 0.647363703498894 LRP5/SLC27A2/FUT8/ATP2B4/GLDC 5 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 1/244 60/18722 0.545409896309903 0.647477210720499 PUM1 1 GO:0009620 response to fungus 1/244 60/18722 0.545409896309903 0.647477210720499 GAPDH 1 GO:0051851 modulation by host of symbiont process 1/244 60/18722 0.545409896309903 0.647477210720499 JUN 1 GO:1903670 regulation of sprouting angiogenesis 1/244 60/18722 0.545409896309903 0.647477210720499 SEMA6A 1 GO:0007292 female gamete generation 2/244 140/18722 0.5469344728226 0.649052610218513 LGR5/ADAMTS1 2 GO:1901990 regulation of mitotic cell cycle phase transition 4/244 299/18722 0.54872762921899 0.650945483615018 ADAMTS1/APP/PBX1/CTDSPL 4 GO:0031503 protein-containing complex localization 3/244 220/18722 0.54893101644924 0.65095175750711 AKAP9/DAG1/IFT27 3 GO:0016571 histone methylation 2/244 141/18722 0.550789626258026 0.652176990930755 JARID2/MLLT6 2 GO:0050921 positive regulation of chemotaxis 2/244 141/18722 0.550789626258026 0.652176990930755 MET/LGMN 2 GO:1903038 negative regulation of leukocyte cell-cell adhesion 2/244 141/18722 0.550789626258026 0.652176990930755 MIA3/GLI3 2 GO:0006900 vesicle budding from membrane 1/244 61/18722 0.551353524286561 0.652176990930755 MIA3 1 GO:0060997 dendritic spine morphogenesis 1/244 61/18722 0.551353524286561 0.652176990930755 PPP1R9A 1 GO:0060998 regulation of dendritic spine development 1/244 61/18722 0.551353524286561 0.652176990930755 PPP1R9A 1 GO:1904356 regulation of telomere maintenance via telomere lengthening 1/244 61/18722 0.551353524286561 0.652176990930755 NAF1 1 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 3/244 221/18722 0.552004373068134 0.652711899928711 TMTC3/USP25/SVIP 3 GO:2000045 regulation of G1/S transition of mitotic cell cycle 2/244 142/18722 0.554621748125284 0.655570886453124 ADAMTS1/CTDSPL 2 GO:0030099 myeloid cell differentiation 5/244 381/18722 0.556294070223006 0.656281045328804 FBN1/JUN/APP/ITGB8/TGFBR3 5 GO:0031124 mRNA 3'-end processing 1/244 62/18722 0.557219755467852 0.656281045328804 APP 1 GO:0032615 interleukin-12 production 1/244 62/18722 0.557219755467852 0.656281045328804 ISL1 1 GO:0032623 interleukin-2 production 1/244 62/18722 0.557219755467852 0.656281045328804 SPTBN1 1 GO:0032655 regulation of interleukin-12 production 1/244 62/18722 0.557219755467852 0.656281045328804 ISL1 1 GO:0032663 regulation of interleukin-2 production 1/244 62/18722 0.557219755467852 0.656281045328804 SPTBN1 1 GO:0032757 positive regulation of interleukin-8 production 1/244 62/18722 0.557219755467852 0.656281045328804 HYAL2 1 GO:0045428 regulation of nitric oxide biosynthetic process 1/244 62/18722 0.557219755467852 0.656281045328804 ATP2B4 1 GO:0070265 necrotic cell death 1/244 62/18722 0.557219755467852 0.656281045328804 ASAH1 1 GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 1/244 62/18722 0.557219755467852 0.656281045328804 DAG1 1 GO:0002274 myeloid leukocyte activation 3/244 223/18722 0.558114009318032 0.656765765465535 APP/ITGB8/HYAL2 3 GO:0038061 NIK/NF-kappaB signaling 2/244 143/18722 0.558430781713544 0.656765765465535 BMP7/APP 2 GO:0062013 positive regulation of small molecule metabolic process 2/244 143/18722 0.558430781713544 0.656765765465535 APP/P2RY6 2 GO:0070555 response to interleukin-1 2/244 143/18722 0.558430781713544 0.656765765465535 APP/HYAL2 2 GO:0006644 phospholipid metabolic process 5/244 383/18722 0.560959614856085 0.659491897134243 CDS1/PGAP1/SACM1L/PIP5K1B/PLPP3 5 GO:0032984 protein-containing complex disassembly 3/244 224/18722 0.561150135236563 0.659491897134243 SVIL/CALM1/SPTBN1 3 GO:0014065 phosphatidylinositol 3-kinase signaling 2/244 144/18722 0.56221667567448 0.660260358526312 PIP5K1B/SERPINE2 2 GO:0001756 somitogenesis 1/244 63/18722 0.563009593606429 0.660260358526312 FOXC1 1 GO:0001947 heart looping 1/244 63/18722 0.563009593606429 0.660260358526312 FOLR1 1 GO:0016239 positive regulation of macroautophagy 1/244 63/18722 0.563009593606429 0.660260358526312 HTT 1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 1/244 63/18722 0.563009593606429 0.660260358526312 ERP29 1 GO:2000756 regulation of peptidyl-lysine acetylation 1/244 63/18722 0.563009593606429 0.660260358526312 ISL1 1 GO:0042692 muscle cell differentiation 5/244 384/18722 0.563283271083042 0.660345639949652 ISL1/ITGB1/RCAN1/HOPX/KRT19 5 GO:0009259 ribonucleotide metabolic process 5/244 385/18722 0.565600783748121 0.662796954908456 SLC26A2/APP/LDHA/GAPDH/ACSS1 5 GO:0007269 neurotransmitter secretion 2/244 145/18722 0.565979383893222 0.662796954908456 PPP1R9A/CALM1 2 GO:0099643 signal release from synapse 2/244 145/18722 0.565979383893222 0.662796954908456 PPP1R9A/CALM1 2 GO:0006650 glycerophospholipid metabolic process 4/244 306/18722 0.567045234923929 0.66364600884433 CDS1/PGAP1/SACM1L/PIP5K1B 4 GO:0051495 positive regulation of cytoskeleton organization 3/244 226/18722 0.567184636789175 0.66364600884433 IQGAP2/MET/AKAP9 3 GO:0006940 regulation of smooth muscle contraction 1/244 64/18722 0.568724029490454 0.66364600884433 ATP2B1 1 GO:0016126 sterol biosynthetic process 1/244 64/18722 0.568724029490454 0.66364600884433 DHCR24 1 GO:0030858 positive regulation of epithelial cell differentiation 1/244 64/18722 0.568724029490454 0.66364600884433 FOXC1 1 GO:0030888 regulation of B cell proliferation 1/244 64/18722 0.568724029490454 0.66364600884433 SLC39A10 1 GO:0045670 regulation of osteoclast differentiation 1/244 64/18722 0.568724029490454 0.66364600884433 FBN1 1 GO:0046854 phosphatidylinositol phosphate biosynthetic process 1/244 64/18722 0.568724029490454 0.66364600884433 PIP5K1B 1 GO:0070542 response to fatty acid 1/244 64/18722 0.568724029490454 0.66364600884433 GLDC 1 GO:0080164 regulation of nitric oxide metabolic process 1/244 64/18722 0.568724029490454 0.66364600884433 ATP2B4 1 GO:0003170 heart valve development 1/244 65/18722 0.574364041110367 0.667619469079825 GJA5 1 GO:0015909 long-chain fatty acid transport 1/244 65/18722 0.574364041110367 0.667619469079825 SLC27A2 1 GO:0035418 protein localization to synapse 1/244 65/18722 0.574364041110367 0.667619469079825 DAG1 1 GO:0038034 signal transduction in absence of ligand 1/244 65/18722 0.574364041110367 0.667619469079825 ITGAV 1 GO:0043489 RNA stabilization 1/244 65/18722 0.574364041110367 0.667619469079825 NAF1 1 GO:0045682 regulation of epidermis development 1/244 65/18722 0.574364041110367 0.667619469079825 FOXC1 1 GO:0046513 ceramide biosynthetic process 1/244 65/18722 0.574364041110367 0.667619469079825 ASAH1 1 GO:0061512 protein localization to cilium 1/244 65/18722 0.574364041110367 0.667619469079825 DZIP1 1 GO:0070613 regulation of protein processing 1/244 65/18722 0.574364041110367 0.667619469079825 SERPINE2 1 GO:0070936 protein K48-linked ubiquitination 1/244 65/18722 0.574364041110367 0.667619469079825 RNF216 1 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 1/244 65/18722 0.574364041110367 0.667619469079825 ITGAV 1 GO:0071695 anatomical structure maturation 3/244 229/18722 0.576140987837745 0.669448120945838 APP/DAG1/RERE 3 GO:0006631 fatty acid metabolic process 5/244 390/18722 0.577094520209794 0.669845493963046 ATP6V1B1/HACD3/SLC27A2/ACSS1/ASAH1 5 GO:0051656 establishment of organelle localization 5/244 390/18722 0.577094520209794 0.669845493963046 ARMCX3/ITGB1/SYNE2/GJA1/HTT 5 GO:1901987 regulation of cell cycle phase transition 5/244 390/18722 0.577094520209794 0.669845493963046 ADAMTS1/APP/PBX1/ATP2B4/CTDSPL 5 GO:0030193 regulation of blood coagulation 1/244 66/18722 0.579930593823508 0.671713757949964 SERPINE2 1 GO:0046626 regulation of insulin receptor signaling pathway 1/244 66/18722 0.579930593823508 0.671713757949964 KANK1 1 GO:0050766 positive regulation of phagocytosis 1/244 66/18722 0.579930593823508 0.671713757949964 LRP1 1 GO:0071300 cellular response to retinoic acid 1/244 66/18722 0.579930593823508 0.671713757949964 SLC6A4 1 GO:0072678 T cell migration 1/244 66/18722 0.579930593823508 0.671713757949964 APP 1 GO:2000573 positive regulation of DNA biosynthetic process 1/244 66/18722 0.579930593823508 0.671713757949964 NAF1 1 GO:0009411 response to UV 2/244 149/18722 0.580797613195669 0.672480957350588 SCARA3/HYAL2 2 GO:0070665 positive regulation of leukocyte proliferation 2/244 150/18722 0.584443875420628 0.674984339907957 IL6ST/SLC39A10 2 GO:0006402 mRNA catabolic process 3/244 232/18722 0.584981342637452 0.674984339907957 TNRC6B/PUM1/DDX5 3 GO:0006513 protein monoubiquitination 1/244 67/18722 0.585424640516639 0.674984339907957 HUWE1 1 GO:0006879 cellular iron ion homeostasis 1/244 67/18722 0.585424640516639 0.674984339907957 SLC46A1 1 GO:0032890 regulation of organic acid transport 1/244 67/18722 0.585424640516639 0.674984339907957 ITGB1 1 GO:0035914 skeletal muscle cell differentiation 1/244 67/18722 0.585424640516639 0.674984339907957 DDX5 1 GO:0043967 histone H4 acetylation 1/244 67/18722 0.585424640516639 0.674984339907957 PHF20 1 GO:0046635 positive regulation of alpha-beta T cell activation 1/244 67/18722 0.585424640516639 0.674984339907957 GLI3 1 GO:0048814 regulation of dendrite morphogenesis 1/244 67/18722 0.585424640516639 0.674984339907957 CUX1 1 GO:0061180 mammary gland epithelium development 1/244 67/18722 0.585424640516639 0.674984339907957 LRP5 1 GO:0061371 determination of heart left/right asymmetry 1/244 67/18722 0.585424640516639 0.674984339907957 FOLR1 1 GO:1903317 regulation of protein maturation 1/244 67/18722 0.585424640516639 0.674984339907957 SERPINE2 1 GO:0018105 peptidyl-serine phosphorylation 4/244 315/18722 0.589985756559237 0.678143081426591 LATS2/APP/AKAP9/ATP2B4 4 GO:0006163 purine nucleotide metabolic process 5/244 396/18722 0.590674615110839 0.678143081426591 SLC26A2/APP/LDHA/GAPDH/ACSS1 5 GO:0019693 ribose phosphate metabolic process 5/244 396/18722 0.590674615110839 0.678143081426591 SLC26A2/APP/LDHA/GAPDH/ACSS1 5 GO:0007585 respiratory gaseous exchange by respiratory system 1/244 68/18722 0.590847121766382 0.678143081426591 FUT8 1 GO:0009247 glycolipid biosynthetic process 1/244 68/18722 0.590847121766382 0.678143081426591 PGAP1 1 GO:0031640 killing of cells of other organism 1/244 68/18722 0.590847121766382 0.678143081426591 GAPDH 1 GO:0034394 protein localization to cell surface 1/244 68/18722 0.590847121766382 0.678143081426591 VCL 1 GO:0042987 amyloid precursor protein catabolic process 1/244 68/18722 0.590847121766382 0.678143081426591 DHCR24 1 GO:0046637 regulation of alpha-beta T cell differentiation 1/244 68/18722 0.590847121766382 0.678143081426591 GLI3 1 GO:0046686 response to cadmium ion 1/244 68/18722 0.590847121766382 0.678143081426591 JUN 1 GO:0051926 negative regulation of calcium ion transport 1/244 68/18722 0.590847121766382 0.678143081426591 CALM1 1 GO:1900046 regulation of hemostasis 1/244 68/18722 0.590847121766382 0.678143081426591 SERPINE2 1 GO:1904888 cranial skeletal system development 1/244 68/18722 0.590847121766382 0.678143081426591 GLI3 1 GO:0008643 carbohydrate transport 2/244 152/18722 0.591666308611817 0.678372466887101 SLC35D1/SLC35A4 2 GO:0016573 histone acetylation 2/244 152/18722 0.591666308611817 0.678372466887101 ISL1/PHF20 2 GO:0098754 detoxification 2/244 152/18722 0.591666308611817 0.678372466887101 BMP7/SOD3 2 GO:0007338 single fertilization 2/244 153/18722 0.595242458073116 0.681903864346707 FOLR1/SPESP1 2 GO:0003143 embryonic heart tube morphogenesis 1/244 69/18722 0.596198965997592 0.681903864346707 FOLR1 1 GO:0007004 telomere maintenance via telomerase 1/244 69/18722 0.596198965997592 0.681903864346707 NAF1 1 GO:0034605 cellular response to heat 1/244 69/18722 0.596198965997592 0.681903864346707 SLC52A3 1 GO:0050688 regulation of defense response to virus 1/244 69/18722 0.596198965997592 0.681903864346707 RNF216 1 GO:0051966 regulation of synaptic transmission, glutamatergic 1/244 69/18722 0.596198965997592 0.681903864346707 SERPINE2 1 GO:1901224 positive regulation of NIK/NF-kappaB signaling 1/244 69/18722 0.596198965997592 0.681903864346707 APP 1 GO:0046395 carboxylic acid catabolic process 3/244 236/18722 0.596585415082607 0.682108446054783 SLC27A2/ATP2B4/GLDC 3 GO:0043410 positive regulation of MAPK cascade 6/244 480/18722 0.598232423277888 0.683753649701266 LRP1/APP/P2RY6/ERP29/WWC1/GCNT2 6 GO:0008360 regulation of cell shape 2/244 154/18722 0.598795222141595 0.683921133109934 DAG1/MYH10 2 GO:0030856 regulation of epithelial cell differentiation 2/244 154/18722 0.598795222141595 0.683921133109934 VCL/FOXC1 2 GO:0031334 positive regulation of protein-containing complex assembly 3/244 237/18722 0.599453407166438 0.68443498816849 IQGAP2/MET/AKAP9 3 GO:0002548 monocyte chemotaxis 1/244 70/18722 0.601481089639719 0.686273215470874 LGMN 1 GO:0045123 cellular extravasation 1/244 70/18722 0.601481089639719 0.686273215470874 ITGB1 1 GO:0016042 lipid catabolic process 4/244 320/18722 0.602420660826324 0.687106661393718 LRP1/NCEH1/SLC27A2/ASAH1 4 GO:1903039 positive regulation of leukocyte cell-cell adhesion 3/244 239/18722 0.60514944485442 0.689979554403756 IL6ST/DPP4/GLI3 3 GO:0046631 alpha-beta T cell activation 2/244 156/18722 0.605830596612484 0.690516593988422 CTSL/GLI3 2 GO:0050818 regulation of coagulation 1/244 71/18722 0.606694397281147 0.691261369440308 SERPINE2 1 GO:0016054 organic acid catabolic process 3/244 240/18722 0.607977408589167 0.692483107322012 SLC27A2/ATP2B4/GLDC 3 GO:0007034 vacuolar transport 2/244 157/18722 0.609313218082519 0.693043694918365 LRP1/HOOK2 2 GO:1902107 positive regulation of leukocyte differentiation 2/244 157/18722 0.609313218082519 0.693043694918365 JUN/GLI3 2 GO:1902600 proton transmembrane transport 2/244 157/18722 0.609313218082519 0.693043694918365 ATP6V1B1/SLC46A1 2 GO:1903708 positive regulation of hemopoiesis 2/244 157/18722 0.609313218082519 0.693043694918365 JUN/GLI3 2 GO:0005977 glycogen metabolic process 1/244 72/18722 0.611839781821568 0.694715108177496 IL6ST 1 GO:0030330 DNA damage response, signal transduction by p53 class mediator 1/244 72/18722 0.611839781821568 0.694715108177496 DDX5 1 GO:0032729 positive regulation of interferon-gamma production 1/244 72/18722 0.611839781821568 0.694715108177496 ISL1 1 GO:0051057 positive regulation of small GTPase mediated signal transduction 1/244 72/18722 0.611839781821568 0.694715108177496 ITGAV 1 GO:0071479 cellular response to ionizing radiation 1/244 72/18722 0.611839781821568 0.694715108177496 HSPA5 1 GO:0018393 internal peptidyl-lysine acetylation 2/244 158/18722 0.612772476092037 0.695293631366862 ISL1/PHF20 2 GO:0043488 regulation of mRNA stability 2/244 158/18722 0.612772476092037 0.695293631366862 TNRC6B/PUM1 2 GO:0034655 nucleobase-containing compound catabolic process 5/244 407/18722 0.614941746282978 0.697514179594707 KCNQ1OT1/TNRC6B/NAF1/PUM1/DDX5 5 GO:0006073 cellular glucan metabolic process 1/244 73/18722 0.616918124622401 0.698550295489045 IL6ST 1 GO:0044042 glucan metabolic process 1/244 73/18722 0.616918124622401 0.698550295489045 IL6ST 1 GO:0070988 demethylation 1/244 73/18722 0.616918124622401 0.698550295489045 JARID2 1 GO:0072089 stem cell proliferation 1/244 73/18722 0.616918124622401 0.698550295489045 GJA1 1 GO:0099518 vesicle cytoskeletal trafficking 1/244 73/18722 0.616918124622401 0.698550295489045 HTT 1 GO:0006325 chromatin organization 5/244 409/18722 0.619263418431639 0.700964379251246 MPHOSPH8/JARID2/HLTF/RERE/DNMT3A 5 GO:0006475 internal protein amino acid acetylation 2/244 160/18722 0.619620964865113 0.70112757938938 ISL1/PHF20 2 GO:0017148 negative regulation of translation 3/244 245/18722 0.621915216797479 0.702772679340869 TNRC6B/GAPDH/PUM1 3 GO:0006635 fatty acid beta-oxidation 1/244 74/18722 0.621930295655279 0.702772679340869 SLC27A2 1 GO:0010822 positive regulation of mitochondrion organization 1/244 74/18722 0.621930295655279 0.702772679340869 HTT 1 GO:0046470 phosphatidylcholine metabolic process 1/244 74/18722 0.621930295655279 0.702772679340869 CDS1 1 GO:0006024 glycosaminoglycan biosynthetic process 1/244 75/18722 0.626877153648635 0.706904024327184 GCNT2 1 GO:0006278 RNA-dependent DNA biosynthetic process 1/244 75/18722 0.626877153648635 0.706904024327184 NAF1 1 GO:0033077 T cell differentiation in thymus 1/244 75/18722 0.626877153648635 0.706904024327184 GLI3 1 GO:0034121 regulation of toll-like receptor signaling pathway 1/244 75/18722 0.626877153648635 0.706904024327184 LGR4 1 GO:0048662 negative regulation of smooth muscle cell proliferation 1/244 75/18722 0.626877153648635 0.706904024327184 SF1 1 GO:1902369 negative regulation of RNA catabolic process 1/244 75/18722 0.626877153648635 0.706904024327184 NAF1 1 GO:0006633 fatty acid biosynthetic process 2/244 163/18722 0.629718958336679 0.709865007579529 HACD3/ACSS1 2 GO:0006809 nitric oxide biosynthetic process 1/244 76/18722 0.631759546232415 0.711677020541554 ATP2B4 1 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 1/244 76/18722 0.631759546232415 0.711677020541554 DDX5 1 GO:2001242 regulation of intrinsic apoptotic signaling pathway 2/244 164/18722 0.633038469898509 0.712873342044723 ERP29/P4HB 2 GO:0072521 purine-containing compound metabolic process 5/244 416/18722 0.634163299755091 0.713895376154583 SLC26A2/APP/LDHA/GAPDH/ACSS1 5 GO:0032418 lysosome localization 1/244 77/18722 0.636578310080923 0.715878277524269 HPS6 1 GO:0140056 organelle localization by membrane tethering 1/244 77/18722 0.636578310080923 0.715878277524269 CALM1 1 GO:1901983 regulation of protein acetylation 1/244 77/18722 0.636578310080923 0.715878277524269 ISL1 1 GO:0030307 positive regulation of cell growth 2/244 166/18722 0.639607968302902 0.718793359727543 LRP1/MACF1 2 GO:0061013 regulation of mRNA catabolic process 2/244 166/18722 0.639607968302902 0.718793359727543 TNRC6B/PUM1 2 GO:1903037 regulation of leukocyte cell-cell adhesion 4/244 336/18722 0.640655034476536 0.719503043592679 IL6ST/MIA3/DPP4/GLI3 4 GO:0009064 glutamine family amino acid metabolic process 1/244 78/18722 0.641334271053852 0.719503043592679 ATP2B4 1 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 1/244 78/18722 0.641334271053852 0.719503043592679 DHCR24 1 GO:0043537 negative regulation of blood vessel endothelial cell migration 1/244 78/18722 0.641334271053852 0.719503043592679 ATP2B4 1 GO:0070373 negative regulation of ERK1 and ERK2 cascade 1/244 78/18722 0.641334271053852 0.719503043592679 SEMA6A 1 GO:0007254 JNK cascade 2/244 167/18722 0.642858033963026 0.720720402457354 APP/HACD3 2 GO:0009451 RNA modification 2/244 167/18722 0.642858033963026 0.720720402457354 NAF1/TARBP1 2 GO:0018209 peptidyl-serine modification 4/244 338/18722 0.645262963851075 0.721943308009814 LATS2/APP/AKAP9/ATP2B4 4 GO:0000245 spliceosomal complex assembly 1/244 79/18722 0.64602824433549 0.721943308009814 SF1 1 GO:0001895 retina homeostasis 1/244 79/18722 0.64602824433549 0.721943308009814 ARMS2 1 GO:0006023 aminoglycan biosynthetic process 1/244 79/18722 0.64602824433549 0.721943308009814 GCNT2 1 GO:0006029 proteoglycan metabolic process 1/244 79/18722 0.64602824433549 0.721943308009814 EXTL2 1 GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 1/244 79/18722 0.64602824433549 0.721943308009814 GAPDH 1 GO:1901184 regulation of ERBB signaling pathway 1/244 79/18722 0.64602824433549 0.721943308009814 LGMN 1 GO:0016482 cytosolic transport 2/244 168/18722 0.646085034627432 0.721943308009814 HOOK2/TMEM87A 2 GO:2000241 regulation of reproductive process 2/244 168/18722 0.646085034627432 0.721943308009814 BMP7/GJA1 2 GO:0006839 mitochondrial transport 3/244 254/18722 0.646145851751937 0.721943308009814 HUWE1/LMAN1/SREBF2 3 GO:0009152 purine ribonucleotide biosynthetic process 2/244 169/18722 0.64928901681375 0.724962184590548 SLC26A2/ACSS1 2 GO:0018394 peptidyl-lysine acetylation 2/244 169/18722 0.64928901681375 0.724962184590548 ISL1/PHF20 2 GO:0032204 regulation of telomere maintenance 1/244 80/18722 0.650661034572155 0.726247336822045 NAF1 1 GO:0010833 telomere maintenance via telomere lengthening 1/244 81/18722 0.655233436007858 0.730358572158013 NAF1 1 GO:0046209 nitric oxide metabolic process 1/244 81/18722 0.655233436007858 0.730358572158013 ATP2B4 1 GO:0051149 positive regulation of muscle cell differentiation 1/244 81/18722 0.655233436007858 0.730358572158013 HOPX 1 GO:2000106 regulation of leukocyte apoptotic process 1/244 81/18722 0.655233436007858 0.730358572158013 SLC39A10 1 GO:0046890 regulation of lipid biosynthetic process 2/244 171/18722 0.655628125241525 0.730550701778112 ASAH1/SF1 2 GO:0042593 glucose homeostasis 3/244 258/18722 0.656558032011076 0.731338879046914 EFNA5/LRP5/LRP1 3 GO:0002221 pattern recognition receptor signaling pathway 2/244 172/18722 0.658763357705697 0.733546727692619 LGR4/PUM1 2 GO:0033500 carbohydrate homeostasis 3/244 259/18722 0.65912660880356 0.733646741246542 EFNA5/LRP5/LRP1 3 GO:0007032 endosome organization 1/244 82/18722 0.659746232618238 0.733646741246542 HOOK2 1 GO:0072527 pyrimidine-containing compound metabolic process 1/244 82/18722 0.659746232618238 0.733646741246542 SLC19A3 1 GO:2001057 reactive nitrogen species metabolic process 1/244 82/18722 0.659746232618238 0.733646741246542 ATP2B4 1 GO:0051091 positive regulation of DNA-binding transcription factor activity 3/244 260/18722 0.661681385627156 0.735549740585533 LRP5/APP/PLPP3 3 GO:0001510 RNA methylation 1/244 83/18722 0.664200198242763 0.737601166416262 TARBP1 1 GO:0043367 CD4-positive, alpha-beta T cell differentiation 1/244 83/18722 0.664200198242763 0.737601166416262 CTSL 1 GO:0061053 somite development 1/244 83/18722 0.664200198242763 0.737601166416262 FOXC1 1 GO:0022900 electron transport chain 2/244 175/18722 0.668032457336277 0.739982072686536 PDIA5/GLDC 2 GO:0006112 energy reserve metabolic process 1/244 84/18722 0.668596096715254 0.739982072686536 IL6ST 1 GO:0009953 dorsal/ventral pattern formation 1/244 84/18722 0.668596096715254 0.739982072686536 GLI3 1 GO:0010660 regulation of muscle cell apoptotic process 1/244 84/18722 0.668596096715254 0.739982072686536 BMP7 1 GO:0015844 monoamine transport 1/244 84/18722 0.668596096715254 0.739982072686536 SLC6A4 1 GO:0032370 positive regulation of lipid transport 1/244 84/18722 0.668596096715254 0.739982072686536 LRP1 1 GO:0042440 pigment metabolic process 1/244 84/18722 0.668596096715254 0.739982072686536 SLC46A1 1 GO:0098586 cellular response to virus 1/244 84/18722 0.668596096715254 0.739982072686536 PUM1 1 GO:1900542 regulation of purine nucleotide metabolic process 1/244 84/18722 0.668596096715254 0.739982072686536 APP 1 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 1/244 84/18722 0.668596096715254 0.739982072686536 CTDSPL 1 GO:0002683 negative regulation of immune system process 5/244 434/18722 0.670812876518901 0.742185559677141 FBN1/MAPKBP1/MIA3/DPP4/GLI3 5 GO:0010507 negative regulation of autophagy 1/244 85/18722 0.672934681992724 0.743781824765588 MET 1 GO:0055013 cardiac muscle cell development 1/244 85/18722 0.672934681992724 0.743781824765588 ISL1 1 GO:0097006 regulation of plasma lipoprotein particle levels 1/244 85/18722 0.672934681992724 0.743781824765588 NCEH1 1 GO:0051302 regulation of cell division 2/244 177/18722 0.674098646810121 0.74423229803097 SVIL/CALM1 2 GO:0071466 cellular response to xenobiotic stimulus 2/244 177/18722 0.674098646810121 0.74423229803097 NCEH1/HSPA5 2 GO:0051607 defense response to virus 3/244 265/18722 0.674248189664698 0.74423229803097 RNF216/PUM1/HYAL2 3 GO:0140546 defense response to symbiont 3/244 265/18722 0.674248189664698 0.74423229803097 RNF216/PUM1/HYAL2 3 GO:0006109 regulation of carbohydrate metabolic process 2/244 178/18722 0.677097976450028 0.745505551275213 APP/P2RY6 2 GO:0048015 phosphatidylinositol-mediated signaling 2/244 178/18722 0.677097976450028 0.745505551275213 PIP5K1B/SERPINE2 2 GO:0006140 regulation of nucleotide metabolic process 1/244 86/18722 0.677216698282566 0.745505551275213 APP 1 GO:0015908 fatty acid transport 1/244 86/18722 0.677216698282566 0.745505551275213 SLC27A2 1 GO:0022406 membrane docking 1/244 86/18722 0.677216698282566 0.745505551275213 CALM1 1 GO:0032413 negative regulation of ion transmembrane transporter activity 1/244 86/18722 0.677216698282566 0.745505551275213 CALM1 1 GO:0034103 regulation of tissue remodeling 1/244 86/18722 0.677216698282566 0.745505551275213 CST3 1 GO:2000117 negative regulation of cysteine-type endopeptidase activity 1/244 86/18722 0.677216698282566 0.745505551275213 DHCR24 1 GO:1903578 regulation of ATP metabolic process 1/244 87/18722 0.681442880168112 0.749906665851446 APP 1 GO:0007033 vacuole organization 2/244 180/18722 0.683029456454706 0.751149529421072 NAGLU/HOOK2 2 GO:0071897 DNA biosynthetic process 2/244 180/18722 0.683029456454706 0.751149529421072 GJA1/NAF1 2 GO:0030101 natural killer cell activation 1/244 88/18722 0.685613952732587 0.752611125457407 PBX1 1 GO:0070098 chemokine-mediated signaling pathway 1/244 88/18722 0.685613952732587 0.752611125457407 FOXC1 1 GO:0006479 protein methylation 2/244 181/18722 0.685961753117752 0.752611125457407 JARID2/MLLT6 2 GO:0008213 protein alkylation 2/244 181/18722 0.685961753117752 0.752611125457407 JARID2/MLLT6 2 GO:0032640 tumor necrosis factor production 2/244 181/18722 0.685961753117752 0.752611125457407 ISL1/APP 2 GO:0032680 regulation of tumor necrosis factor production 2/244 181/18722 0.685961753117752 0.752611125457407 ISL1/APP 2 GO:0099504 synaptic vesicle cycle 2/244 181/18722 0.685961753117752 0.752611125457407 NLGN4X/CALM1 2 GO:0009260 ribonucleotide biosynthetic process 2/244 182/18722 0.688871854901581 0.755299604673538 SLC26A2/ACSS1 2 GO:0048017 inositol lipid-mediated signaling 2/244 182/18722 0.688871854901581 0.755299604673538 PIP5K1B/SERPINE2 2 GO:0010657 muscle cell apoptotic process 1/244 89/18722 0.689730631681457 0.755484951901756 BMP7 1 GO:0046330 positive regulation of JNK cascade 1/244 89/18722 0.689730631681457 0.755484951901756 APP 1 GO:0051781 positive regulation of cell division 1/244 89/18722 0.689730631681457 0.755484951901756 SVIL 1 GO:0048872 homeostasis of number of cells 3/244 272/18722 0.691262351279853 0.756910391971208 LGR4/TGFBR3/OCIAD2 3 GO:0046700 heterocycle catabolic process 5/244 445/18722 0.691994152969426 0.757459289359604 KCNQ1OT1/TNRC6B/NAF1/PUM1/DDX5 5 GO:0034249 negative regulation of cellular amide metabolic process 3/244 273/18722 0.693637891633778 0.757662295347346 TNRC6B/GAPDH/PUM1 3 GO:0006400 tRNA modification 1/244 90/18722 0.693793623463227 0.757662295347346 TARBP1 1 GO:0034644 cellular response to UV 1/244 90/18722 0.693793623463227 0.757662295347346 HYAL2 1 GO:0035278 miRNA mediated inhibition of translation 1/244 90/18722 0.693793623463227 0.757662295347346 TNRC6B 1 GO:0040033 negative regulation of translation, ncRNA-mediated 1/244 90/18722 0.693793623463227 0.757662295347346 TNRC6B 1 GO:0045638 negative regulation of myeloid cell differentiation 1/244 90/18722 0.693793623463227 0.757662295347346 FBN1 1 GO:0048477 oogenesis 1/244 90/18722 0.693793623463227 0.757662295347346 LGR5 1 GO:0051251 positive regulation of lymphocyte activation 4/244 362/18722 0.697497210421564 0.760020786551936 IL6ST/SLC39A10/DPP4/GLI3 4 GO:0002065 columnar/cuboidal epithelial cell differentiation 1/244 91/18722 0.697803625388677 0.760020786551936 IL6ST 1 GO:0006885 regulation of pH 1/244 91/18722 0.697803625388677 0.760020786551936 ATP6V1B1 1 GO:0042147 retrograde transport, endosome to Golgi 1/244 91/18722 0.697803625388677 0.760020786551936 TMEM87A 1 GO:0045582 positive regulation of T cell differentiation 1/244 91/18722 0.697803625388677 0.760020786551936 GLI3 1 GO:0045974 regulation of translation, ncRNA-mediated 1/244 91/18722 0.697803625388677 0.760020786551936 TNRC6B 1 GO:0051952 regulation of amine transport 1/244 91/18722 0.697803625388677 0.760020786551936 ITGB1 1 GO:0051983 regulation of chromosome segregation 1/244 91/18722 0.697803625388677 0.760020786551936 PUM1 1 GO:0071478 cellular response to radiation 2/244 186/18722 0.700291894646319 0.761721008211786 HSPA5/HYAL2 2 GO:0071706 tumor necrosis factor superfamily cytokine production 2/244 186/18722 0.700291894646319 0.761721008211786 ISL1/APP 2 GO:1902115 regulation of organelle assembly 2/244 186/18722 0.700291894646319 0.761721008211786 DZIP1/HTT 2 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 2/244 186/18722 0.700291894646319 0.761721008211786 ISL1/APP 2 GO:0035249 synaptic transmission, glutamatergic 1/244 92/18722 0.70176132574857 0.762562075532341 SERPINE2 1 GO:0048525 negative regulation of viral process 1/244 92/18722 0.70176132574857 0.762562075532341 MPHOSPH8 1 GO:0070509 calcium ion import 1/244 92/18722 0.70176132574857 0.762562075532341 ATP2B4 1 GO:0033044 regulation of chromosome organization 2/244 187/18722 0.703092222738866 0.763567687338333 MPHOSPH8/NAF1 2 GO:0044270 cellular nitrogen compound catabolic process 5/244 451/18722 0.703151497834995 0.763567687338333 KCNQ1OT1/TNRC6B/NAF1/PUM1/DDX5 5 GO:0007589 body fluid secretion 1/244 93/18722 0.705667403929855 0.765288148288285 KCNN4 1 GO:0032088 negative regulation of NF-kappaB transcription factor activity 1/244 93/18722 0.705667403929855 0.765288148288285 BMP7 1 GO:1901796 regulation of signal transduction by p53 class mediator 1/244 93/18722 0.705667403929855 0.765288148288285 DDX5 1 GO:1902807 negative regulation of cell cycle G1/S phase transition 1/244 93/18722 0.705667403929855 0.765288148288285 CTDSPL 1 GO:1902105 regulation of leukocyte differentiation 3/244 279/18722 0.707603365764628 0.766690631304635 FBN1/JUN/GLI3 3 GO:0009615 response to virus 4/244 367/18722 0.707660585741618 0.766690631304635 RNF216/ITGB8/PUM1/HYAL2 4 GO:0140694 non-membrane-bounded organelle assembly 4/244 367/18722 0.707660585741618 0.766690631304635 CDS1/PRRC2C/ITGB1/KRT19 4 GO:0001738 morphogenesis of a polarized epithelium 1/244 94/18722 0.709522530530377 0.767948298854683 LAMA5 1 GO:0002690 positive regulation of leukocyte chemotaxis 1/244 94/18722 0.709522530530377 0.767948298854683 LGMN 1 GO:0030316 osteoclast differentiation 1/244 94/18722 0.709522530530377 0.767948298854683 FBN1 1 GO:0021700 developmental maturation 3/244 280/18722 0.70988314381976 0.768085614287695 APP/DAG1/RERE 3 GO:0046390 ribose phosphate biosynthetic process 2/244 190/18722 0.711363338857733 0.76943381549918 SLC26A2/ACSS1 2 GO:0045666 positive regulation of neuron differentiation 1/244 95/18722 0.713327367472109 0.771304287434468 BMP7 1 GO:0006164 purine nucleotide biosynthetic process 2/244 191/18722 0.714077384143713 0.771861277729026 SLC26A2/ACSS1 2 GO:0006637 acyl-CoA metabolic process 1/244 96/18722 0.717082568112942 0.774091103422841 ACSS1 1 GO:0035383 thioester metabolic process 1/244 96/18722 0.717082568112942 0.774091103422841 ACSS1 1 GO:0042472 inner ear morphogenesis 1/244 96/18722 0.717082568112942 0.774091103422841 ATP6V1B1 1 GO:0044264 cellular polysaccharide metabolic process 1/244 96/18722 0.717082568112942 0.774091103422841 IL6ST 1 GO:0043255 regulation of carbohydrate biosynthetic process 1/244 97/18722 0.720788777357034 0.777070840680844 P2RY6 1 GO:1901216 positive regulation of neuron death 1/244 97/18722 0.720788777357034 0.777070840680844 JUN 1 GO:1990868 response to chemokine 1/244 97/18722 0.720788777357034 0.777070840680844 FOXC1 1 GO:1990869 cellular response to chemokine 1/244 97/18722 0.720788777357034 0.777070840680844 FOXC1 1 GO:0030098 lymphocyte differentiation 4/244 374/18722 0.721471744715026 0.77755203448133 CTSL/ITGB1/PBX1/GLI3 4 GO:0070301 cellular response to hydrogen peroxide 1/244 98/18722 0.724446631763739 0.780502174418244 MET 1 GO:0018205 peptidyl-lysine modification 4/244 376/18722 0.725328503838516 0.781196153265606 ISL1/JARID2/PHF20/MLLT6 4 GO:0006006 glucose metabolic process 2/244 196/18722 0.727329303012553 0.782083854928677 LRP5/GAPDH 2 GO:0097193 intrinsic apoptotic signaling pathway 3/244 288/18722 0.727633543790549 0.782083854928677 ERP29/P4HB/DDX5 3 GO:0007631 feeding behavior 1/244 99/18722 0.72805675965515 0.782083854928677 APP 1 GO:0015837 amine transport 1/244 99/18722 0.72805675965515 0.782083854928677 ITGB1 1 GO:0030838 positive regulation of actin filament polymerization 1/244 99/18722 0.72805675965515 0.782083854928677 IQGAP2 1 GO:0042100 B cell proliferation 1/244 99/18722 0.72805675965515 0.782083854928677 SLC39A10 1 GO:0051153 regulation of striated muscle cell differentiation 1/244 99/18722 0.72805675965515 0.782083854928677 HOPX 1 GO:0060996 dendritic spine development 1/244 99/18722 0.72805675965515 0.782083854928677 PPP1R9A 1 GO:0019439 aromatic compound catabolic process 5/244 467/18722 0.731527053052135 0.785141280567055 KCNQ1OT1/TNRC6B/NAF1/PUM1/DDX5 5 GO:0009062 fatty acid catabolic process 1/244 100/18722 0.731619781222252 0.785141280567055 SLC27A2 1 GO:0045807 positive regulation of endocytosis 1/244 100/18722 0.731619781222252 0.785141280567055 LRP1 1 GO:0071375 cellular response to peptide hormone stimulus 3/244 290/18722 0.731936570993166 0.785224803226752 FBN1/KANK1/ATP2B1 3 GO:0006417 regulation of translation 5/244 468/18722 0.733233924216155 0.786359880866282 APP/TNRC6B/GAPDH/PUM1/NEMF 5 GO:0042102 positive regulation of T cell proliferation 1/244 101/18722 0.735136308629715 0.788142874439557 IL6ST 1 GO:0072522 purine-containing compound biosynthetic process 2/244 200/18722 0.737554622732734 0.79021991858486 SLC26A2/ACSS1 2 GO:0099003 vesicle-mediated transport in synapse 2/244 200/18722 0.737554622732734 0.79021991858486 NLGN4X/CALM1 2 GO:0035710 CD4-positive, alpha-beta T cell activation 1/244 102/18722 0.738606946119342 0.790574079787674 CTSL 1 GO:0062014 negative regulation of small molecule metabolic process 1/244 102/18722 0.738606946119342 0.790574079787674 ATP2B4 1 GO:1904063 negative regulation of cation transmembrane transport 1/244 102/18722 0.738606946119342 0.790574079787674 CALM1 1 GO:0006473 protein acetylation 2/244 201/18722 0.740059523718152 0.791870919875561 ISL1/PHF20 2 GO:0019395 fatty acid oxidation 1/244 103/18722 0.742032290112193 0.792691191582792 SLC27A2 1 GO:0030004 cellular monovalent inorganic cation homeostasis 1/244 103/18722 0.742032290112193 0.792691191582792 SLC1A3 1 GO:0030593 neutrophil chemotaxis 1/244 103/18722 0.742032290112193 0.792691191582792 DPP4 1 GO:0045639 positive regulation of myeloid cell differentiation 1/244 103/18722 0.742032290112193 0.792691191582792 JUN 1 GO:0046425 regulation of receptor signaling pathway via JAK-STAT 1/244 103/18722 0.742032290112193 0.792691191582792 OCIAD2 1 GO:0016051 carbohydrate biosynthetic process 2/244 202/18722 0.742544055899893 0.792980099995791 P2RY6/FUT8 2 GO:0050727 regulation of inflammatory response 4/244 386/18722 0.744020254440808 0.794298426280862 IL6ST/ISL1/APP/HYAL2 4 GO:0032869 cellular response to insulin stimulus 2/244 203/18722 0.745008322150177 0.79449461099924 KANK1/ATP2B1 2 GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 1/244 104/18722 0.745412929309391 0.79449461099924 P2RY6 1 GO:0032006 regulation of TOR signaling 1/244 104/18722 0.745412929309391 0.79449461099924 SLC38A9 1 GO:0045621 positive regulation of lymphocyte differentiation 1/244 104/18722 0.745412929309391 0.79449461099924 GLI3 1 GO:0046634 regulation of alpha-beta T cell activation 1/244 104/18722 0.745412929309391 0.79449461099924 GLI3 1 GO:0016079 synaptic vesicle exocytosis 1/244 105/18722 0.74874944479164 0.797533444274012 CALM1 1 GO:2001022 positive regulation of response to DNA damage stimulus 1/244 105/18722 0.74874944479164 0.797533444274012 DDX5 1 GO:0001824 blastocyst development 1/244 106/18722 0.752042410117462 0.800521982392608 HOPX 1 GO:0042116 macrophage activation 1/244 106/18722 0.752042410117462 0.800521982392608 APP 1 GO:0016050 vesicle organization 3/244 300/18722 0.75265628540094 0.800915982457089 MIA3/HOOK2/SERPINE2 3 GO:0046486 glycerolipid metabolic process 4/244 392/18722 0.754765146902532 0.802421855223635 CDS1/PGAP1/SACM1L/PIP5K1B 4 GO:0005976 polysaccharide metabolic process 1/244 107/18722 0.755292391420177 0.802421855223635 IL6ST 1 GO:0006275 regulation of DNA replication 1/244 107/18722 0.755292391420177 0.802421855223635 JUN 1 GO:0008637 apoptotic mitochondrial changes 1/244 107/18722 0.755292391420177 0.802421855223635 JUN 1 GO:0031532 actin cytoskeleton reorganization 1/244 107/18722 0.755292391420177 0.802421855223635 IQGAP2 1 GO:0002832 negative regulation of response to biotic stimulus 1/244 108/18722 0.75849994750363 0.805048716891773 MAPKBP1 1 GO:0007173 epidermal growth factor receptor signaling pathway 1/244 108/18722 0.75849994750363 0.805048716891773 EFEMP1 1 GO:0034440 lipid oxidation 1/244 108/18722 0.75849994750363 0.805048716891773 SLC27A2 1 GO:0032410 negative regulation of transporter activity 1/244 109/18722 0.761665629936697 0.8071411409596 CALM1 1 GO:0034766 negative regulation of ion transmembrane transport 1/244 109/18722 0.761665629936697 0.8071411409596 CALM1 1 GO:0031396 regulation of protein ubiquitination 2/244 210/18722 0.761699536858101 0.8071411409596 HSPA5/HUWE1 2 GO:0045637 regulation of myeloid cell differentiation 2/244 210/18722 0.761699536858101 0.8071411409596 FBN1/JUN 2 GO:0050866 negative regulation of cell activation 2/244 210/18722 0.761699536858101 0.8071411409596 GLI3/SERPINE2 2 GO:0009408 response to heat 1/244 110/18722 0.764789983146575 0.809371943516794 SLC52A3 1 GO:0018958 phenol-containing compound metabolic process 1/244 110/18722 0.764789983146575 0.809371943516794 CPQ 1 GO:0030317 flagellated sperm motility 1/244 110/18722 0.764789983146575 0.809371943516794 ATP2B4 1 GO:0097722 sperm motility 1/244 110/18722 0.764789983146575 0.809371943516794 ATP2B4 1 GO:0009117 nucleotide metabolic process 5/244 489/18722 0.767278731834135 0.811744337671271 SLC26A2/APP/LDHA/GAPDH/ACSS1 5 GO:0001938 positive regulation of endothelial cell proliferation 1/244 111/18722 0.767873544510868 0.811850858192636 NRP2 1 GO:0006805 xenobiotic metabolic process 1/244 111/18722 0.767873544510868 0.811850858192636 NCEH1 1 GO:0001676 long-chain fatty acid metabolic process 1/244 112/18722 0.770916844448505 0.813497993210593 SLC27A2 1 GO:0002526 acute inflammatory response 1/244 112/18722 0.770916844448505 0.813497993210593 IL6ST 1 GO:0002821 positive regulation of adaptive immune response 1/244 112/18722 0.770916844448505 0.813497993210593 IL6ST 1 GO:0032609 interferon-gamma production 1/244 112/18722 0.770916844448505 0.813497993210593 ISL1 1 GO:0032649 regulation of interferon-gamma production 1/244 112/18722 0.770916844448505 0.813497993210593 ISL1 1 GO:0043406 positive regulation of MAP kinase activity 1/244 112/18722 0.770916844448505 0.813497993210593 ERP29 1 GO:0060326 cell chemotaxis 3/244 310/18722 0.772076511486888 0.814460165889539 MET/DPP4/LGMN 3 GO:0007601 visual perception 2/244 215/18722 0.773037183974567 0.815211869878186 TACSTD2/EFEMP1 2 GO:0044106 cellular amine metabolic process 1/244 113/18722 0.77392040650947 0.815358273738416 ATP2B4 1 GO:0044344 cellular response to fibroblast growth factor stimulus 1/244 113/18722 0.77392040650947 0.815358273738416 HYAL2 1 GO:0071347 cellular response to interleukin-1 1/244 113/18722 0.77392040650947 0.815358273738416 HYAL2 1 GO:1901361 organic cyclic compound catabolic process 5/244 495/18722 0.776380788703769 0.817688228102751 KCNQ1OT1/TNRC6B/NAF1/PUM1/DDX5 5 GO:1901800 positive regulation of proteasomal protein catabolic process 1/244 114/18722 0.7768847474634 0.817694836695943 TMTC3 1 GO:1904892 regulation of receptor signaling pathway via STAT 1/244 114/18722 0.7768847474634 0.817694836695943 OCIAD2 1 GO:0006753 nucleoside phosphate metabolic process 5/244 497/18722 0.779353887193698 0.820031019314279 SLC26A2/APP/LDHA/GAPDH/ACSS1 5 GO:0090630 activation of GTPase activity 1/244 115/18722 0.779810377387032 0.820248687610047 SYDE2 1 GO:0050953 sensory perception of light stimulus 2/244 219/18722 0.781766989918199 0.821970268450058 TACSTD2/EFEMP1 2 GO:0007006 mitochondrial membrane organization 1/244 116/18722 0.782697799750527 0.821970268450058 CALM1 1 GO:0008286 insulin receptor signaling pathway 1/244 116/18722 0.782697799750527 0.821970268450058 KANK1 1 GO:0031123 RNA 3'-end processing 1/244 116/18722 0.782697799750527 0.821970268450058 APP 1 GO:0033559 unsaturated fatty acid metabolic process 1/244 116/18722 0.782697799750527 0.821970268450058 ATP6V1B1 1 GO:0002696 positive regulation of leukocyte activation 4/244 409/18722 0.783329763866118 0.822371119509285 IL6ST/SLC39A10/DPP4/GLI3 4 GO:0022618 ribonucleoprotein complex assembly 2/244 220/18722 0.783903099766539 0.822447505055187 NAF1/SF1 2 GO:0097529 myeloid leukocyte migration 2/244 220/18722 0.783903099766539 0.822447505055187 DPP4/LGMN 2 GO:0014902 myotube differentiation 1/244 117/18722 0.785547511502697 0.823909710436598 RCAN1 1 GO:0009308 amine metabolic process 1/244 118/18722 0.788360003155121 0.826332047964187 ATP2B4 1 GO:0071346 cellular response to interferon-gamma 1/244 118/18722 0.788360003155121 0.826332047964187 GAPDH 1 GO:2001234 negative regulation of apoptotic signaling pathway 2/244 224/18722 0.792265528736596 0.830160882470808 ITGAV/HTT 2 GO:0030218 erythrocyte differentiation 1/244 120/18722 0.793875256518091 0.831582433190452 TGFBR3 1 GO:0050670 regulation of lymphocyte proliferation 2/244 225/18722 0.794311195350287 0.831773928591792 IL6ST/SLC39A10 2 GO:0002224 toll-like receptor signaling pathway 1/244 121/18722 0.796578967807715 0.83361735293508 LGR4 1 GO:1904019 epithelial cell apoptotic process 1/244 121/18722 0.796578967807715 0.83361735293508 DNMT3A 1 GO:0032944 regulation of mononuclear cell proliferation 2/244 227/18722 0.798349388720502 0.834814627917418 IL6ST/SLC39A10 2 GO:0071826 ribonucleoprotein complex subunit organization 2/244 227/18722 0.798349388720502 0.834814627917418 NAF1/SF1 2 GO:0019730 antimicrobial humoral response 1/244 122/18722 0.799247358316554 0.834814627917418 GAPDH 1 GO:0050868 negative regulation of T cell activation 1/244 122/18722 0.799247358316554 0.834814627917418 GLI3 1 GO:0072329 monocarboxylic acid catabolic process 1/244 122/18722 0.799247358316554 0.834814627917418 SLC27A2 1 GO:1990266 neutrophil migration 1/244 122/18722 0.799247358316554 0.834814627917418 DPP4 1 GO:0050867 positive regulation of cell activation 4/244 420/18722 0.80036987020326 0.835721446929746 IL6ST/SLC39A10/DPP4/GLI3 4 GO:0006690 icosanoid metabolic process 1/244 123/18722 0.801880887594552 0.836426156553961 ATP6V1B1 1 GO:0050852 T cell receptor signaling pathway 1/244 123/18722 0.801880887594552 0.836426156553961 KCNN4 1 GO:0071482 cellular response to light stimulus 1/244 123/18722 0.801880887594552 0.836426156553961 HYAL2 1 GO:0002831 regulation of response to biotic stimulus 3/244 327/18722 0.802226635640685 0.836426156553961 MAPKBP1/RNF216/PUM1 3 GO:0071356 cellular response to tumor necrosis factor 2/244 229/18722 0.802317481880123 0.836426156553961 ASAH1/HYAL2 2 GO:0030595 leukocyte chemotaxis 2/244 230/18722 0.804275523468532 0.837935754634621 DPP4/LGMN 2 GO:0045055 regulated exocytosis 2/244 230/18722 0.804275523468532 0.837935754634621 CALM1/RAB11FIP1 2 GO:0050863 regulation of T cell activation 3/244 329/18722 0.805545126804945 0.838992483892567 IL6ST/DPP4/GLI3 3 GO:0051053 negative regulation of DNA metabolic process 1/244 125/18722 0.807045170961122 0.839756311519394 GJA1 1 GO:0060294 cilium movement involved in cell motility 1/244 125/18722 0.807045170961122 0.839756311519394 ATP2B4 1 GO:0071621 granulocyte chemotaxis 1/244 125/18722 0.807045170961122 0.839756311519394 DPP4 1 GO:0031929 TOR signaling 1/244 126/18722 0.809576814682447 0.841857409191937 SLC38A9 1 GO:0032874 positive regulation of stress-activated MAPK cascade 1/244 126/18722 0.809576814682447 0.841857409191937 APP 1 GO:0008033 tRNA processing 1/244 127/18722 0.812075376589174 0.844188449057901 TARBP1 1 GO:0062012 regulation of small molecule metabolic process 3/244 334/18722 0.81363778501333 0.845456950011496 APP/P2RY6/ATP2B4 3 GO:2000116 regulation of cysteine-type endopeptidase activity 2/244 235/18722 0.813810204773695 0.845456950011496 DHCR24/LGMN 2 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 1/244 128/18722 0.814541287216345 0.845949010680439 APP 1 GO:0000209 protein polyubiquitination 2/244 236/18722 0.815666826907807 0.846850298015498 RNF216/HUWE1 2 GO:0034101 erythrocyte homeostasis 1/244 129/18722 0.816974971518765 0.847940542138554 TGFBR3 1 GO:0006352 DNA-templated transcription, initiation 1/244 130/18722 0.819376848943034 0.849896567432705 JUN 1 GO:0043467 regulation of generation of precursor metabolites and energy 1/244 130/18722 0.819376848943034 0.849896567432705 APP 1 GO:0051403 stress-activated MAPK cascade 2/244 239/18722 0.821138096545897 0.85118605212928 APP/HACD3 2 GO:0072593 reactive oxygen species metabolic process 2/244 239/18722 0.821138096545897 0.85118605212928 BMP7/SOD3 2 GO:0000723 telomere maintenance 1/244 131/18722 0.821747333498644 0.851280497439011 NAF1 1 GO:0050853 B cell receptor signaling pathway 1/244 131/18722 0.821747333498644 0.851280497439011 SLC39A10 1 GO:0050851 antigen receptor-mediated signaling pathway 2/244 240/18722 0.822929362831248 0.852236333521425 SLC39A10/KCNN4 2 GO:0006997 nucleus organization 1/244 133/18722 0.826395753276585 0.854550081442652 SF1 1 GO:0010565 regulation of cellular ketone metabolic process 1/244 133/18722 0.826395753276585 0.854550081442652 ATP2B4 1 GO:0046328 regulation of JNK cascade 1/244 133/18722 0.826395753276585 0.854550081442652 APP 1 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 1/244 133/18722 0.826395753276585 0.854550081442652 TMTC3 1 GO:1903320 regulation of protein modification by small protein conjugation or removal 2/244 242/18722 0.826463834091524 0.854550081442652 HSPA5/HUWE1 2 GO:0043543 protein acylation 2/244 243/18722 0.828207263171883 0.855758759901708 ISL1/PHF20 2 GO:0051090 regulation of DNA-binding transcription factor activity 4/244 440/18722 0.82857721013315 0.855758759901708 LRP5/BMP7/APP/PLPP3 4 GO:0032147 activation of protein kinase activity 1/244 134/18722 0.828674489959597 0.855758759901708 EFNA5 1 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 1/244 134/18722 0.828674489959597 0.855758759901708 SVIP 1 GO:0070663 regulation of leukocyte proliferation 2/244 245/18722 0.831647067040413 0.858558674927677 IL6ST/SLC39A10 2 GO:1903305 regulation of regulated secretory pathway 1/244 136/18722 0.833142981750427 0.859832863703488 CALM1 1 GO:0031098 stress-activated protein kinase signaling cascade 2/244 247/18722 0.835024874406664 0.861282053906198 APP/HACD3 2 GO:0034754 cellular hormone metabolic process 1/244 137/18722 0.835333507546882 0.861282053906198 RDH14 1 GO:0045471 response to ethanol 1/244 137/18722 0.835333507546882 0.861282053906198 DNMT3A 1 GO:0001539 cilium or flagellum-dependent cell motility 1/244 138/18722 0.837495392085949 0.862969538536979 ATP2B4 1 GO:0060285 cilium-dependent cell motility 1/244 138/18722 0.837495392085949 0.862969538536979 ATP2B4 1 GO:0016579 protein deubiquitination 1/244 139/18722 0.839629008332775 0.864896840558464 USP25 1 GO:0006887 exocytosis 3/244 352/18722 0.840454028547866 0.865475380071541 CALM1/MIA3/RAB11FIP1 3 GO:0030183 B cell differentiation 1/244 141/18722 0.843812903688136 0.868118096906455 ITGB1 1 GO:0034341 response to interferon-gamma 1/244 141/18722 0.843812903688136 0.868118096906455 GAPDH 1 GO:0048284 organelle fusion 1/244 141/18722 0.843812903688136 0.868118096906455 HUWE1 1 GO:0034612 response to tumor necrosis factor 2/244 253/18722 0.844795173198625 0.868856631965784 ASAH1/HYAL2 2 GO:0009165 nucleotide biosynthetic process 2/244 254/18722 0.846371755114868 0.870205753225112 SLC26A2/ACSS1 2 GO:0034763 negative regulation of transmembrane transport 1/244 143/18722 0.847888081714503 0.871266591034287 CALM1 1 GO:0006338 chromatin remodeling 2/244 255/18722 0.847933827792955 0.871266591034287 JARID2/RERE 2 GO:1901293 nucleoside phosphate biosynthetic process 2/244 256/18722 0.849481499658864 0.872583997461403 SLC26A2/ACSS1 2 GO:0051052 regulation of DNA metabolic process 3/244 359/18722 0.849950166328845 0.872792577048933 MPHOSPH8/GJA1/NAF1 3 GO:0030217 T cell differentiation 2/244 257/18722 0.851014878789898 0.873612899626243 CTSL/GLI3 2 GO:0031348 negative regulation of defense response 2/244 258/18722 0.852534072905358 0.874899114168334 ISL1/MAPKBP1 2 GO:0010675 regulation of cellular carbohydrate metabolic process 1/244 146/18722 0.853803138771182 0.875654529963204 P2RY6 1 GO:0045580 regulation of T cell differentiation 1/244 146/18722 0.853803138771182 0.875654529963204 GLI3 1 GO:0097530 granulocyte migration 1/244 148/18722 0.857618675117879 0.879019016356005 DPP4 1 GO:2001056 positive regulation of cysteine-type endopeptidase activity 1/244 148/18722 0.857618675117879 0.879019016356005 LGMN 1 GO:1903706 regulation of hemopoiesis 3/244 367/18722 0.86019973626459 0.881389564504348 FBN1/JUN/GLI3 3 GO:0032868 response to insulin 2/244 264/18722 0.861357337229337 0.882300564256733 KANK1/ATP2B1 2 GO:0002764 immune response-regulating signaling pathway 4/244 468/18722 0.862460441109825 0.88315519148859 SLC39A10/KCNN4/LGR4/PUM1 4 GO:0043535 regulation of blood vessel endothelial cell migration 1/244 151/18722 0.863156817057296 0.883592928613793 ATP2B4 1 GO:0050871 positive regulation of B cell activation 1/244 152/18722 0.864954767444352 0.884882118873643 SLC39A10 1 GO:0051092 positive regulation of NF-kappaB transcription factor activity 1/244 152/18722 0.864954767444352 0.884882118873643 APP 1 GO:0120254 olefinic compound metabolic process 1/244 153/18722 0.866729190532321 0.886421450385685 RDH14 1 GO:0051168 nuclear export 1/244 154/18722 0.868480392940103 0.887936083136646 NEMF 1 GO:0051147 regulation of muscle cell differentiation 1/244 155/18722 0.870208677306897 0.889426349496256 HOPX 1 GO:0002262 myeloid cell homeostasis 1/244 157/18722 0.87359768288377 0.891780672866129 TGFBR3 1 GO:0051250 negative regulation of lymphocyte activation 1/244 157/18722 0.87359768288377 0.891780672866129 GLI3 1 GO:0070646 protein modification by small protein removal 1/244 157/18722 0.87359768288377 0.891780672866129 USP25 1 GO:2000377 regulation of reactive oxygen species metabolic process 1/244 157/18722 0.87359768288377 0.891780672866129 BMP7 1 GO:0032200 telomere organization 1/244 159/18722 0.876898550720743 0.894872247723094 NAF1 1 GO:0007281 germ cell development 2/244 278/18722 0.88010147334794 0.897595645787516 LGR5/DZIP1 2 GO:0051650 establishment of vesicle localization 1/244 161/18722 0.880113563824521 0.897595645787516 HTT 1 GO:0002263 cell activation involved in immune response 2/244 279/18722 0.881346947048902 0.898574641018521 LRP1/APP 2 GO:0051100 negative regulation of binding 1/244 162/18722 0.881689572144484 0.89864514083957 JUN 1 GO:0042110 T cell activation 4/244 487/18722 0.882062963801146 0.898746945442036 IL6ST/CTSL/DPP4/GLI3 4 GO:0072331 signal transduction by p53 class mediator 1/244 163/18722 0.883244946303791 0.89967231666282 DDX5 1 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 1/244 164/18722 0.884779955361492 0.900956595388244 SVIP 1 GO:0044262 cellular carbohydrate metabolic process 2/244 283/18722 0.886210603009978 0.902133841849686 IL6ST/P2RY6 2 GO:0002833 positive regulation of response to biotic stimulus 1/244 168/18722 0.890721600409135 0.906335469006313 PUM1 1 GO:0140014 mitotic nuclear division 2/244 287/18722 0.890889703253314 0.906335469006313 LRP5/BMP7 2 GO:0046651 lymphocyte proliferation 2/244 288/18722 0.892031354718089 0.907216041969557 IL6ST/SLC39A10 2 GO:0042129 regulation of T cell proliferation 1/244 171/18722 0.894976674389023 0.909225140729559 IL6ST 1 GO:0048469 cell maturation 1/244 171/18722 0.894976674389023 0.909225140729559 APP 1 GO:0002429 immune response-activating cell surface receptor signaling pathway 2/244 291/18722 0.895390309008171 0.909225140729559 SLC39A10/KCNN4 2 GO:0002757 immune response-activating signal transduction 2/244 291/18722 0.895390309008171 0.909225140729559 SLC39A10/KCNN4 2 GO:0032943 mononuclear cell proliferation 2/244 291/18722 0.895390309008171 0.909225140729559 IL6ST/SLC39A10 2 GO:0042770 signal transduction in response to DNA damage 1/244 172/18722 0.896358038814072 0.909926634396985 DDX5 1 GO:0010948 negative regulation of cell cycle process 2/244 294/18722 0.898652196790991 0.911973785872513 BMP7/CTDSPL 2 GO:0045619 regulation of lymphocyte differentiation 1/244 174/18722 0.899066717242693 0.912112760993977 GLI3 1 GO:0003341 cilium movement 1/244 175/18722 0.900394500345604 0.913177879054214 ATP2B4 1 GO:0050728 negative regulation of inflammatory response 1/244 176/18722 0.901704887034323 0.914224701880526 ISL1 1 GO:0051648 vesicle localization 1/244 177/18722 0.902998104308324 0.915253476482774 HTT 1 GO:0006399 tRNA metabolic process 1/244 179/18722 0.905533923898481 0.916975184570234 TARBP1 1 GO:0010950 positive regulation of endopeptidase activity 1/244 179/18722 0.905533923898481 0.916975184570234 LGMN 1 GO:1901991 negative regulation of mitotic cell cycle phase transition 1/244 179/18722 0.905533923898481 0.916975184570234 CTDSPL 1 GO:0002819 regulation of adaptive immune response 1/244 183/18722 0.910409195289151 0.921628039346935 IL6ST 1 GO:0043433 negative regulation of DNA-binding transcription factor activity 1/244 185/18722 0.912752027436261 0.92371517159087 BMP7 1 GO:0002695 negative regulation of leukocyte activation 1/244 187/18722 0.915033838209314 0.925739283360777 GLI3 1 GO:0001906 cell killing 1/244 188/18722 0.916152356875455 0.926585609323713 GAPDH 1 GO:0002768 immune response-regulating cell surface receptor signaling pathway 2/244 315/18722 0.918967828928641 0.92914716487985 SLC39A10/KCNN4 2 GO:0032872 regulation of stress-activated MAPK cascade 1/244 192/18722 0.920481684617676 0.930391515119559 APP 1 GO:0070661 leukocyte proliferation 2/244 318/18722 0.921537696802675 0.931172469770477 IL6ST/SLC39A10 2 GO:0050777 negative regulation of immune response 1/244 194/18722 0.922562120814687 0.931921035658488 MAPKBP1 1 GO:0070302 regulation of stress-activated protein kinase signaling cascade 1/244 195/18722 0.923581920173561 0.932664471324622 APP 1 GO:0050864 regulation of B cell activation 1/244 198/18722 0.926561760781636 0.935386158503366 SLC39A10 1 GO:0042098 T cell proliferation 1/244 199/18722 0.927529096690148 0.936075126450807 IL6ST 1 GO:0006403 RNA localization 1/244 201/18722 0.929425863380773 0.937413562636347 NAF1 1 GO:0051054 positive regulation of DNA metabolic process 1/244 201/18722 0.929425863380773 0.937413562636347 NAF1 1 GO:0017157 regulation of exocytosis 1/244 202/18722 0.930355623616996 0.938063387298389 CALM1 1 GO:0019216 regulation of lipid metabolic process 2/244 331/18722 0.931814670039611 0.939246320782258 ASAH1/SF1 2 GO:0042113 B cell activation 2/244 334/18722 0.933999174041851 0.941159547961215 SLC39A10/ITGB1 2 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 1/244 209/18722 0.936531147417659 0.94342162796273 DHCR24 1 GO:0042180 cellular ketone metabolic process 1/244 211/18722 0.938193196570307 0.944806265378495 ATP2B4 1 GO:0032496 response to lipopolysaccharide 2/244 343/18722 0.940163054812667 0.946499938147801 JUN/GJA1 2 GO:2001020 regulation of response to DNA damage stimulus 1/244 219/18722 0.944419008534734 0.950493372755019 DDX5 1 GO:0019221 cytokine-mediated signaling pathway 3/244 472/18722 0.947634161521805 0.953437187618081 IL6ST/P4HB/FOXC1 3 GO:0006364 rRNA processing 1/244 225/18722 0.948674803290649 0.954192042734335 NAF1 1 GO:0002237 response to molecule of bacterial origin 2/244 363/18722 0.951965844286127 0.956922852012289 JUN/GJA1 2 GO:0016197 endosomal transport 1/244 230/18722 0.951972246874064 0.956922852012289 TMEM87A 1 GO:0034660 ncRNA metabolic process 3/244 485/18722 0.953905032697404 0.958572457933844 KCNQ1OT1/NAF1/TARBP1 3 GO:0016072 rRNA metabolic process 1/244 236/18722 0.955651811667073 0.960034195395292 NAF1 1 GO:0002253 activation of immune response 2/244 375/18722 0.957946754081754 0.96204554826181 SLC39A10/KCNN4 2 GO:0071216 cellular response to biotic stimulus 1/244 246/18722 0.961170950057803 0.964988616526104 HSPA5 1 GO:1901988 negative regulation of cell cycle phase transition 1/244 249/18722 0.962689171186997 0.966217659291531 CTDSPL 1 GO:0034470 ncRNA processing 2/244 395/18722 0.966366564851387 0.969612376214247 NAF1/TARBP1 2 GO:0006260 DNA replication 1/244 260/18722 0.967767266016036 0.970721378549662 JUN 1 GO:0090305 nucleic acid phosphodiester bond hydrolysis 1/244 261/18722 0.968193264666891 0.970852324594264 APEX2 1 GO:0000280 nuclear division 2/244 439/18722 0.979573710269105 0.981964372161159 LRP5/BMP7 2 GO:0042254 ribosome biogenesis 1/244 299/18722 0.980825703016589 0.982919566975453 NAF1 1 GO:0006310 DNA recombination 1/244 305/18722 0.982300030095361 0.984096920394315 APEX2 1 GO:0022613 ribonucleoprotein complex biogenesis 2/244 463/18722 0.984496894176668 0.985997194228751 NAF1/SF1 2 GO:0006959 humoral immune response 1/244 317/18722 0.984918501870994 0.986018640930477 GAPDH 1 GO:0015980 energy derivation by oxidation of organic compounds 1/244 318/18722 0.985118441319158 0.986018640930477 IL6ST 1 GO:0048285 organelle fission 2/244 488/18722 0.988397656580925 0.988999603996626 LRP5/BMP7 2 GO:0007059 chromosome segregation 1/244 346/18722 0.989761654064441 0.990062951371614 PUM1 1 GO:0042742 defense response to bacterium 1/244 350/18722 0.990294748282261 0.990294748282261 MAPKBP1 1