ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	geneName	Count
hsa05200	Pathways in cancer	44/409	326/5868	1.20863361203434e-05	0.0022843175267449	3912/3915/999/1956/3685/4233/1284/6502/11211/2263/1441/3911/3655/1438/1857/5468/2034/6513/9618/3480/3265/2737/8313/5747/595/1050/8323/5467/4193/5154/1021/6256/10342/3688/1282/2950/675/332/7184/2271/6934/898/5228/572	LAMB1/LAMC1/CDH1/EGFR/ITGAV/MET/COL4A2/SKP2/FZD10/FGFR2/CSF3R/LAMA5/ITGA6/CSF2RA/DVL3/PPARG/EPAS1/SLC2A1/TRAF4/IGF1R/HRAS/GLI3/AXIN2/PTK2/CCND1/CEBPA/FZD6/PPARD/MDM2/PDGFA/CDK6/RXRA/TFG/ITGB1/COL4A1/GSTP1/BRCA2/BIRC5/HSP90B1/FH/TCF7L2/CCNE1/PGF/BAD	44
hsa04520	Adherens junction	15/409	73/5868	0.000117817819425469	0.00685300700257764	999/1956/4233/4008/10580/2241/3480/7082/5792/56288/8976/7525/6885/87/6934	CDH1/EGFR/MET/LMO7/SORBS1/FER/IGF1R/TJP1/PTPRF/PARD3/WASL/YES1/MAP3K7/ACTN1/TCF7L2	15
hsa05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/409	74/5868	0.000138540222709909	0.00685300700257764	3691/2697/1605/3685/1829/1832/3693/1824/3655/3696/87/4000/3688/5318/6934	ITGB4/GJA1/DAG1/ITGAV/DSG2/DSP/ITGB5/DSC2/ITGA6/ITGB8/ACTN1/LMNA/ITGB1/PKP2/TCF7L2	15
hsa04810	Regulation of actin cytoskeleton	30/409	213/5868	0.000145037185239738	0.00685300700257764	3691/1956/4628/3685/2263/8394/85477/3693/3655/2768/3696/23191/1793/22808/56924/7114/3985/55970/3265/10787/8976/5747/87/5154/81624/3688/10451/55740/2934/8395	ITGB4/EGFR/MYH10/ITGAV/FGFR2/PIP5K1A/SCIN/ITGB5/ITGA6/GNA12/ITGB8/CYFIP1/DOCK1/MRAS/PAK6/TMSB4X/LIMK2/GNG12/HRAS/NCKAP1/WASL/PTK2/ACTN1/PDGFA/DIAPH3/ITGB1/VAV3/ENAH/GSN/PIP5K1B	30
hsa04510	Focal adhesion	28/409	200/5868	0.000267407177959837	0.00916640939247444	3912/3691/3915/1956/3685/4233/1284/3911/3693/3655/3696/1793/56924/3480/2321/3265/5747/595/87/5154/2317/3688/1282/394/10451/5228/572/5170	LAMB1/ITGB4/LAMC1/EGFR/ITGAV/MET/COL4A2/LAMA5/ITGB5/ITGA6/ITGB8/DOCK1/PAK6/IGF1R/FLT1/HRAS/PTK2/CCND1/ACTN1/PDGFA/FLNB/ITGB1/COL4A1/ARHGAP5/VAV3/PGF/BAD/PDPK1	28
hsa04144	Endocytosis	28/409	201/5868	0.000290997123570617	0.00916640939247444	1956/4233/153/2263/8394/7037/2348/2065/3106/3105/3480/2321/1601/3949/161/3265/22905/5584/3107/56288/3133/4193/1213/11031/10617/30845/3561/8395	EGFR/MET/ADRB1/FGFR2/PIP5K1A/TFRC/FOLR1/ERBB3/HLA-B/HLA-A/IGF1R/FLT1/DAB2/LDLR/AP2A2/HRAS/EPN2/PRKCI/HLA-C/PARD3/HLA-E/MDM2/CLTC/RAB31/STAMBP/EHD3/IL2RG/PIP5K1B	28
hsa04360	Axon guidance	20/409	129/5868	0.000540340757663781	0.0138145415545767	5364/80031/57556/4233/8829/5921/6405/54910/1946/2770/56924/3985/3265/1942/23654/2050/10725/5747/1808/3688	PLXNB1/SEMA6D/SEMA6A/MET/NRP1/RASA1/SEMA3F/SEMA4C/EFNA5/GNAI1/PAK6/LIMK2/HRAS/EFNA1/PLXNB2/EPHB4/NFAT5/PTK2/DPYSL2/ITGB1	20
hsa04142	Lysosome	19/409	121/5868	0.000629706410366667	0.0138145415545767	1515/4669/138050/2548/1514/2799/1201/4891/1174/1213/5641/4126/2517/51606/5660/950/10053/4758/2990	CTSV/NAGLU/HGSNAT/GAA/CTSL/GNS/CLN3/SLC11A2/AP1S1/CLTC/LGMN/MANBA/FUCA1/ATP6V1H/PSAP/SCARB2/AP1M2/NEU1/GUSB	19
hsa05222	Small cell lung cancer	15/409	85/5868	0.000672690200328629	0.0138145415545767	3912/3915/3685/1284/6502/3911/3655/9618/5747/595/1021/6256/3688/1282/898	LAMB1/LAMC1/ITGAV/COL4A2/SKP2/LAMA5/ITGA6/TRAF4/PTK2/CCND1/CDK6/RXRA/ITGB1/COL4A1/CCNE1	15
hsa04530	Tight junction	20/409	132/5868	0.000730928124580777	0.0138145415545767	4628/154810/1364/149461/83700/22808/2770/2017/3265/5584/7082/9414/56288/7525/5872/87/1366/5516/23136/50848	MYH10/AMOTL1/CLDN4/CLDN19/JAM3/MRAS/GNAI1/CTTN/HRAS/PRKCI/TJP1/TJP2/PARD3/YES1/RAB13/ACTN1/CLDN7/PPP2CB/EPB41L3/F11R	20
hsa05215	Prostate cancer	15/409	89/5868	0.00110395993363765	0.0189680388597741	1956/2263/3480/3265/595/4193/5154/2950/64764/10488/7184/6934/898/572/5170	EGFR/FGFR2/IGF1R/HRAS/CCND1/MDM2/PDGFA/GSTP1/CREB3L2/CREB3/HSP90B1/TCF7L2/CCNE1/BAD/PDPK1	15
hsa00510	N-Glycan biosynthesis	10/409	49/5868	0.0016965998355108	0.0267214474092951	4248/7991/7841/29929/1798/2530/3703/6185/1650/23193	MGAT3/TUSC3/MOGS/ALG6/DPAGT1/FUT8/STT3A/RPN2/DDOST/GANAB	10
hsa05216	Thyroid cancer	7/409	29/5868	0.00308905633917007	0.0449101267771649	999/5468/3265/595/6256/10342/6934	CDH1/PPARG/HRAS/CCND1/RXRA/TFG/TCF7L2	7
hsa04514	Cell adhesion molecules (CAMs)	18/409	133/5868	0.00472862702901976	0.0625088305428882	999/3685/3655/23705/1364/3696/149461/83700/3106/3105/3107/5792/9019/3133/1366/3688/2734/50848	CDH1/ITGAV/ITGA6/CADM1/CLDN4/ITGB8/CLDN19/JAM3/HLA-B/HLA-A/HLA-C/PTPRF/MPZL1/HLA-E/CLDN7/ITGB1/GLG1/F11R	18
hsa04141	Protein processing in endoplasmic reticulum	21/409	165/5868	0.00496101829705462	0.0625088305428882	6238/7991/7841/10970/440275/3998/55757/7466/5589/22824/5034/3703/10277/6185/7184/11231/5887/64374/1650/23193/573	RRBP1/TUSC3/MOGS/CKAP4/EIF2AK4/LMAN1/UGGT2/WFS1/PRKCSH/HSPA4L/P4HB/STT3A/UBE4B/RPN2/HSP90B1/SEC63/RAD23B/SIL1/DDOST/GANAB/BAG1	21
hsa04512	ECM-receptor interaction	13/409	85/5868	0.00555060387285343	0.0655665082480811	3912/3691/3915/1605/3685/1284/3911/3693/3655/3696/3688/1282/3161	LAMB1/ITGB4/LAMC1/DAG1/ITGAV/COL4A2/LAMA5/ITGB5/ITGA6/ITGB8/ITGB1/COL4A1/HMMR	13
hsa00480	Glutathione metabolism	9/409	50/5868	0.00687354792471632	0.076417679868905	4259/2937/2954/3417/6611/2950/2730/2941/6240	MGST3/GSS/GSTZ1/IDH1/SMS/GSTP1/GCLM/GSTA4/RRM1	9
hsa05100	Bacterial invasion of epithelial cells	10/409	70/5868	0.0222168177754895	0.23327658664264	999/4233/1793/2549/2017/8976/5747/1213/3688/23607	CDH1/MET/DOCK1/GAB1/CTTN/WASL/PTK2/CLTC/ITGB1/CD2AP	10
hsa05218	Melanoma	10/409	71/5868	0.0243150043247336	0.240820692933014	999/1956/4233/3480/3265/595/4193/5154/1021/572	CDH1/EGFR/MET/IGF1R/HRAS/CCND1/MDM2/PDGFA/CDK6/BAD	10
hsa05213	Endometrial cancer	8/409	52/5868	0.0260969793991843	0.240820692933014	999/1956/3265/8313/595/6934/572/5170	CDH1/EGFR/HRAS/AXIN2/CCND1/TCF7L2/BAD/PDPK1	8
hsa00511	Other glycan degradation	4/409	17/5868	0.0267578547703349	0.240820692933014	23324/4126/2517/4758	MAN2B2/MANBA/FUCA1/NEU1	4
hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	5/409	26/5868	0.0312377817537689	0.268360943248287	2651/84002/10331/11041/10402	GCNT2/B3GNT5/B3GNT3/B4GAT1/ST3GAL6	5
hsa00531	Glycosaminoglycan degradation	4/409	19/5868	0.0390483304365357	0.320875410978489	4669/138050/2799/2990	NAGLU/HGSNAT/GNS/GUSB	4
hsa05120	Epithelial cell signaling in Helicobacter pylori infection	9/409	68/5868	0.0450067412200145	0.354428087107614	1956/4233/525/83700/7082/6352/51606/245973/50848	EGFR/MET/ATP6V1B1/JAM3/TJP1/CCL5/ATP6V1H/ATP6V1C2/F11R	9
hsa04145	Phagosome	16/409	153/5868	0.0658978746295547	0.498187932199433	3685/81035/3693/525/7037/1514/3106/3105/4973/3107/3133/1535/3688/51606/245973/1783	ITGAV/COLEC12/ITGB5/ATP6V1B1/TFRC/CTSL/HLA-B/HLA-A/OLR1/HLA-C/HLA-E/CYBA/ITGB1/ATP6V1H/ATP6V1C2/DYNC1LI2	16
hsa05219	Bladder cancer	6/409	42/5868	0.0688571167743832	0.500538271936862	999/1956/3265/595/4193/5228	CDH1/EGFR/HRAS/CCND1/MDM2/PGF	6
hsa05223	Non-small cell lung cancer	7/409	54/5868	0.0791627916227937	0.538421951048311	1956/3265/595/1021/6256/572/5170	EGFR/HRAS/CCND1/CDK6/RXRA/BAD/PDPK1	7
hsa05214	Glioma	8/409	65/5868	0.0804778635340777	0.538421951048311	1956/818/3480/3265/595/4193/5154/1021	EGFR/CAMK2G/IGF1R/HRAS/CCND1/MDM2/PDGFA/CDK6	8
hsa04962	Vasopressin-regulated water reabsorption	6/409	44/5868	0.0826150083619102	0.538421951048311	51164/64764/10488/140735/10671/1783	DCTN4/CREB3L2/CREB3/DYNLL2/DCTN6/DYNC1LI2	6
hsa00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	4/409	25/5868	0.0920550097670722	0.556808512973434	80055/128869/5281/8733	PGAP1/PIGU/PIGF/GPAA1	4
hsa04310	Wnt signaling pathway	15/409	150/5868	0.0985945861080446	0.556808512973434	4041/11211/1857/6477/4040/818/10725/8313/595/6885/6907/8323/5467/5516/6934	LRP5/FZD10/DVL3/SIAH1/LRP6/CAMK2G/NFAT5/AXIN2/CCND1/MAP3K7/TBL1X/FZD6/PPARD/PPP2CB/TCF7L2	15
hsa04115	p53 signaling pathway	8/409	68/5868	0.0987112729547703	0.556808512973434	6477/64065/595/4193/1021/545/51512/898	SIAH1/PERP/CCND1/MDM2/CDK6/ATR/GTSE1/CCNE1	8
hsa00270	Cysteine and methionine metabolism	5/409	36/5868	0.102056831623491	0.556808512973434	6611/7263/1786/1036/3945	SMS/TST/DNMT1/CDO1/LDHB	5
hsa00564	Glycerophospholipid metabolism	9/409	80/5868	0.102981769328086	0.556808512973434	8613/23761/57678/1040/10554/81579/10423/56994/10434	PLPP3/PISD/GPAM/CDS1/AGPAT1/PLA2G12A/CDIPT/CHPT1/LYPLA1	9
hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	4/409	26/5868	0.103112687587673	0.556808512973434	2135/26035/64131/2132	EXTL2/GLCE/XYLT1/EXT2	4
hsa04670	Leukocyte transendothelial migration	12/409	116/5868	0.108097833556234	0.567513626170228	1364/149461/83700/2770/5747/87/1535/1366/3688/394/10451/50848	CLDN4/CLDN19/JAM3/GNAI1/PTK2/ACTN1/CYBA/CLDN7/ITGB1/ARHGAP5/VAV3/F11R	12
hsa05211	Renal cell carcinoma	8/409	70/5868	0.112059472884264	0.572411902030428	4233/2034/6513/2549/56924/3265/2271/5228	MET/EPAS1/SLC2A1/GAB1/PAK6/HRAS/FH/PGF	8
hsa04122	Sulfur relay system	2/409	10/5868	0.150561468153304	0.740493913289266	7263/4338	TST/MOCS2	2
hsa00020	Citrate cycle (TCA cycle)	4/409	30/5868	0.152800331313658	0.740493913289266	48/3417/8803/2271	ACO1/IDH1/SUCLA2/FH	4
hsa04612	Antigen processing and presentation	8/409	76/5868	0.157559534381903	0.744468799954493	567/1514/3106/3105/3107/3133/5641/10197	B2M/CTSL/HLA-B/HLA-A/HLA-C/HLA-E/LGMN/PSME3	8
hsa05414	Dilated cardiomyopathy	9/409	90/5868	0.173480087687712	0.748105823698971	3691/1605/3685/153/3693/3655/3696/4000/3688	ITGB4/DAG1/ITGAV/ADRB1/ITGB5/ITGA6/ITGB8/LMNA/ITGB1	9
hsa00071	Fatty acid degradation	5/409	43/5868	0.177314539436368	0.748105823698971	35/1632/501/37/3032	ACADS/ECI1/ALDH7A1/ACADVL/HADHB	5
hsa00250	Alanine, aspartate and glutamate metabolism	4/409	32/5868	0.180467258756902	0.748105823698971	158/2673/5471/445	ADSL/GFPT1/PPAT/ASS1	4
hsa00260	Glycine, serine and threonine metabolism	4/409	32/5868	0.180467258756902	0.748105823698971	2731/29968/501/211	GLDC/PSAT1/ALDH7A1/ALAS1	4
hsa00640	Propanoate metabolism	4/409	32/5868	0.180467258756902	0.748105823698971	84532/501/8803/3945	ACSS1/ALDH7A1/SUCLA2/LDHB	4
hsa05217	Basal cell carcinoma	6/409	55/5868	0.182078666085464	0.748105823698971	11211/1857/2737/8313/8323/6934	FZD10/DVL3/GLI3/AXIN2/FZD6/TCF7L2	6
hsa04974	Protein digestion and absorption	8/409	81/5868	0.201133149764013	0.775537278735383	7373/1284/4311/6510/3783/1282/54407/1803	COL14A1/COL4A2/MME/SLC1A5/KCNN4/COL4A1/SLC38A2/DPP4	8
hsa00562	Inositol phosphate metabolism	6/409	57/5868	0.203871797166418	0.775537278735383	8394/51477/8867/10423/3636/8395	PIP5K1A/ISYNA1/SYNJ1/CDIPT/INPPL1/PIP5K1B	6
hsa05221	Acute myeloid leukemia	6/409	57/5868	0.203871797166418	0.775537278735383	3265/595/1050/5467/6934/572	HRAS/CCND1/CEBPA/PPARD/TCF7L2/BAD	6
hsa03320	PPAR signaling pathway	7/409	70/5868	0.213375335948359	0.775537278735383	11001/10580/5468/4973/5467/6256/5170	SLC27A2/SORBS1/PPARG/OLR1/PPARD/RXRA/PDPK1	7
hsa04730	Long-term depression	7/409	70/5868	0.213375335948359	0.775537278735383	2768/2770/2767/3480/3265/81579/5516	GNA12/GNAI1/GNA11/IGF1R/HRAS/PLA2G12A/PPP2CB	7
hsa05416	Viral myocarditis	7/409	70/5868	0.213375335948359	0.775537278735383	1605/4628/3106/3105/3107/595/3133	DAG1/MYH10/HLA-B/HLA-A/HLA-C/CCND1/HLA-E	7
hsa05410	Hypertrophic cardiomyopathy (HCM)	8/409	83/5868	0.219805298261521	0.783833988140141	3691/1605/3685/3693/3655/3696/4000/3688	ITGB4/DAG1/ITGAV/ITGB5/ITGA6/ITGB8/LMNA/ITGB1	8
hsa03450	Non-homologous end-joining	2/409	13/5868	0.228240433768138	0.797567677255086	2237/10111	FEN1/RAD50	2
hsa04977	Vitamin digestion and absorption	3/409	24/5868	0.23209641401603	0.797567677255086	80704/6573/113278	SLC19A3/SLC19A1/SLC52A3	3
hsa04110	Cell cycle	11/409	124/5868	0.245138552341302	0.827342614151896	6502/7465/4171/1028/595/4193/1021/545/7029/898/890	SKP2/WEE1/MCM2/CDKN1C/CCND1/MDM2/CDK6/ATR/TFDP2/CCNE1/CCNA2	11
hsa05330	Allograft rejection	4/409	37/5868	0.255600390913211	0.843774266204439	3106/3105/3107/3133	HLA-B/HLA-A/HLA-C/HLA-E	4
hsa04012	ErbB signaling pathway	8/409	87/5868	0.258936018200304	0.843774266204439	1956/2549/56924/818/2065/3265/5747/572	EGFR/GAB1/PAK6/CAMK2G/ERBB3/HRAS/PTK2/BAD	8
hsa00561	Glycerolipid metabolism	5/409	50/5868	0.267578288106856	0.851131813516687	8613/57678/10554/501/231	PLPP3/GPAM/AGPAT1/ALDH7A1/AKR1B1	5
hsa04916	Melanogenesis	9/409	101/5868	0.270200575719583	0.851131813516687	11211/1857/2770/818/3265/8323/64764/10488/6934	FZD10/DVL3/GNAI1/CAMK2G/HRAS/FZD6/CREB3L2/CREB3/TCF7L2	9
hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	2/409	15/5868	0.281424697321447	0.857891416028281	2530/11041	FUT8/B4GAT1	2
hsa00900	Terpenoid backbone biosynthesis	2/409	15/5868	0.281424697321447	0.857891416028281	57107/4598	PDSS2/MVK	2
hsa04540	Gap junction	8/409	90/5868	0.289578538775744	0.865516848026415	2697/1956/153/2770/2767/3265/7082/5154	GJA1/EGFR/ADRB1/GNAI1/GNA11/HRAS/TJP1/PDGFA	8
hsa00600	Sphingolipid metabolism	4/409	40/5868	0.30333407579386	0.865516848026415	8613/8560/55304/4758	PLPP3/DEGS1/SPTLC3/NEU1	4
hsa00620	Pyruvate metabolism	4/409	40/5868	0.30333407579386	0.865516848026415	84532/501/231/3945	ACSS1/ALDH7A1/AKR1B1/LDHB	4
hsa04146	Peroxisome	7/409	79/5868	0.31140266555022	0.865516848026415	11001/4598/3417/10478/5052/26063/25824	SLC27A2/MVK/IDH1/SLC25A17/PRDX1/DECR2/PRDX5	7
hsa05145	Toxoplasmosis	11/409	132/5868	0.313166510125705	0.865516848026415	3912/3915/3911/3655/2770/3949/81579/3588/6885/3688/572	LAMB1/LAMC1/LAMA5/ITGA6/GNAI1/LDLR/PLA2G12A/IL10RB/MAP3K7/ITGB1/BAD	11
hsa05332	Graft-versus-host disease	4/409	41/5868	0.31948053510213	0.865516848026415	3106/3105/3107/3133	HLA-B/HLA-A/HLA-C/HLA-E	4
hsa05110	Vibrio cholerae infection	5/409	54/5868	0.323067855350723	0.865516848026415	525/7082/9414/51606/245973	ATP6V1B1/TJP1/TJP2/ATP6V1H/ATP6V1C2	5
hsa05160	Hepatitis C	11/409	134/5868	0.330879462877206	0.865516848026415	1956/1364/440275/149461/3949/3265/6256/1366/5516/10197/572	EGFR/CLDN4/EIF2AK4/CLDN19/LDLR/HRAS/RXRA/CLDN7/PPP2CB/PSME3/BAD	11
hsa04666	Fc gamma R-mediated phagocytosis	8/409	94/5868	0.331705173703348	0.865516848026415	8613/8394/85477/3985/8976/10451/2934/8395	PLPP3/PIP5K1A/SCIN/LIMK2/WASL/VAV3/GSN/PIP5K1B	8
hsa00450	Selenocompound metabolism	2/409	17/5868	0.334300158232425	0.865516848026415	10587/7296	TXNRD2/TXNRD1	2
hsa04614	Renin-angiotensin system	2/409	17/5868	0.334300158232425	0.865516848026415	2028/4311	ENPEP/MME	2
hsa05130	Pathogenic Escherichia coli infection	5/409	56/5868	0.351314772125368	0.875205779365432	999/2017/8976/3875/3688	CDH1/CTTN/WASL/KRT18/ITGB1	5
hsa00860	Porphyrin and chlorophyll metabolism	4/409	43/5868	0.351934599109909	0.875205779365432	210/5498/211/2990	ALAD/PPOX/ALAS1/GUSB	4
hsa04940	Type I diabetes mellitus	4/409	43/5868	0.351934599109909	0.875205779365432	3106/3105/3107/3133	HLA-B/HLA-A/HLA-C/HLA-E	4
hsa05212	Pancreatic cancer	6/409	70/5868	0.361750908980968	0.88793404931692	1956/595/1021/675/5228/572	EGFR/CCND1/CDK6/BRCA2/PGF/BAD	6
hsa03050	Proteasome	4/409	44/5868	0.368182508525026	0.892134539887564	5707/5693/10197/9861	PSMD1/PSMB5/PSME3/PSMD6	4
hsa04621	NOD-like receptor signaling pathway	5/409	58/5868	0.379679133393858	0.904651965992118	6885/257397/7205/6352/7184	MAP3K7/TAB3/TRIP6/CCL5/HSP90B1	5
hsa00100	Steroid biosynthesis	2/409	19/5868	0.385988707126802	0.904651965992118	6713/1718	SQLE/DHCR24	2
hsa00040	Pentose and glucuronate interconversions	3/409	32/5868	0.387707985425193	0.904651965992118	231/6120/2990	AKR1B1/RPE/GUSB	3
hsa03410	Base excision repair	3/409	33/5868	0.406990321713899	0.92649954967423	10038/27301/2237	PARP2/APEX2/FEN1	3
hsa04010	MAPK signaling pathway	20/409	268/5868	0.408230389282077	0.92649954967423	1956/2263/2768/5921/4763/1852/22808/55970/3265/81579/6885/5154/9175/1848/2317/9448/1847/51295/11072/8986	EGFR/FGFR2/GNA12/RASA1/NF1/DUSP9/MRAS/GNG12/HRAS/PLA2G12A/MAP3K7/PDGFA/MAP3K13/DUSP6/FLNB/MAP4K4/DUSP5/ECSIT/DUSP14/RPS6KA4	20
hsa04640	Hematopoietic cell lineage	7/409	88/5868	0.415944788480198	0.92649954967423	1441/3655/1438/7037/4311/100133941/966	CSF3R/ITGA6/CSF2RA/TFRC/MME/CD24/CD59	7
hsa04330	Notch signaling pathway	4/409	47/5868	0.416679691652431	0.92649954967423	23220/4854/1857/3516	DTX4/NOTCH3/DVL3/RBPJ	4
hsa05210	Colorectal cancer	5/409	62/5868	0.436165062039186	0.952391897684717	8313/595/332/6934/572	AXIN2/CCND1/BIRC5/TCF7L2/BAD	5
hsa05323	Rheumatoid arthritis	7/409	91/5868	0.450859789441314	0.952391897684717	525/1514/2321/6352/51606/245973/5228	ATP6V1B1/CTSL/FLT1/CCL5/ATP6V1H/ATP6V1C2/PGF	7
hsa00410	beta-Alanine metabolism	2/409	22/5868	0.459955842025318	0.952391897684717	501/6611	ALDH7A1/SMS	2
hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	2/409	22/5868	0.459955842025318	0.952391897684717	79586/64131	CHPF/XYLT1	2
hsa05146	Amoebiasis	8/409	106/5868	0.461415275518767	0.952391897684717	3912/3915/1284/3911/2767/5747/87/1282	LAMB1/LAMC1/COL4A2/LAMA5/GNA11/PTK2/ACTN1/COL4A1	8
hsa04070	Phosphatidylinositol signaling system	6/409	78/5868	0.463319724036451	0.952391897684717	8394/1040/8867/10423/3636/8395	PIP5K1A/CDS1/SYNJ1/CDIPT/INPPL1/PIP5K1B	6
hsa00565	Ether lipid metabolism	3/409	36/5868	0.463598172417957	0.952391897684717	8613/81579/56994	PLPP3/PLA2G12A/CHPT1	3
hsa05320	Autoimmune thyroid disease	4/409	52/5868	0.495270611700087	0.999999999999755	3106/3105/3107/3133	HLA-B/HLA-A/HLA-C/HLA-E	4
hsa04320	Dorso-ventral axis formation	2/409	24/5868	0.506298547061902	0.999999999999755	1956/4854	EGFR/NOTCH3	2
hsa00430	Taurine and hypotaurine metabolism	1/409	10/5868	0.514733752771018	0.999999999999755	1036	CDO1	1
hsa00330	Arginine and proline metabolism	4/409	54/5868	0.52546566927374	0.999999999999755	501/1159/6611/445	ALDH7A1/CKMT1B/SMS/ASS1	4
hsa04350	TGF-beta signaling pathway	6/409	84/5868	0.536781119028963	0.999999999999755	655/4052/93/3397/5516/4090	BMP7/LTBP1/ACVR2B/ID1/PPP2CB/SMAD5	6
hsa00240	Pyrimidine metabolism	7/409	99/5868	0.541370041756067	0.999999999999755	7083/4833/1841/10587/4830/7296/6240	TK1/NME4/DTYMK/TXNRD2/NME1/TXNRD1/RRM1	7
hsa00350	Tyrosine metabolism	3/409	41/5868	0.552134812853428	0.999999999999755	1312/2954/51451	COMT/GSTZ1/LCMT1	3
hsa04976	Bile secretion	5/409	71/5868	0.557539994273124	0.999999999999755	9429/6522/6513/3949/6256	ABCG2/SLC4A2/SLC2A1/LDLR/RXRA	5
hsa00030	Pentose phosphate pathway	2/409	27/5868	0.570779578830651	0.999999999999755	22934/6120	RPIA/RPE	2
hsa00052	Galactose metabolism	2/409	27/5868	0.570779578830651	0.999999999999755	2548/231	GAA/AKR1B1	2
hsa04966	Collecting duct acid secretion	2/409	27/5868	0.570779578830651	0.999999999999755	525/245973	ATP6V1B1/ATP6V1C2	2
hsa05220	Chronic myeloid leukemia	5/409	73/5868	0.582765783363497	0.999999999999755	3265/595/4193/1021/572	HRAS/CCND1/MDM2/CDK6/BAD	5
hsa03440	Homologous recombination	2/409	28/5868	0.590874607128254	0.999999999999755	675/10111	BRCA2/RAD50	2
hsa04970	Salivary secretion	6/409	89/5868	0.59455122138876	0.999999999999755	153/6522/55503/490/3783/1471	ADRB1/SLC4A2/TRPV6/ATP2B1/KCNN4/CST3	6
hsa00280	Valine, leucine and isoleucine degradation	3/409	44/5868	0.600916290172446	0.999999999999755	35/501/3032	ACADS/ALDH7A1/HADHB	3
hsa00310	Lysine degradation	3/409	44/5868	0.600916290172446	0.999999999999755	5352/501/387893	PLOD2/ALDH7A1/KMT5A	3
hsa04120	Ubiquitin mediated proteolysis	9/409	135/5868	0.60536973209758	0.999999999999755	6502/1642/6477/9886/4193/10277/4591/55236/10075	SKP2/DDB1/SIAH1/RHOBTB1/MDM2/UBE4B/TRIM37/UBA6/HUWE1	9
hsa00340	Histidine metabolism	2/409	29/5868	0.610261568599236	0.999999999999755	501/51451	ALDH7A1/LCMT1	2
hsa04370	VEGF signaling pathway	5/409	76/5868	0.619107881024866	0.999999999999755	3265/81579/10725/5747/572	HRAS/PLA2G12A/NFAT5/PTK2/BAD	5
hsa05131	Shigellosis	4/409	61/5868	0.623536179190495	0.999999999999755	1793/2017/8976/3688	DOCK1/CTTN/WASL/ITGB1	4
hsa00512	Mucin type O-Glycan biosynthesis	2/409	30/5868	0.628941316027862	0.999999999999755	374378/63917	GALNT18/GALNT11	2
hsa00591	Linoleic acid metabolism	2/409	30/5868	0.628941316027862	0.999999999999755	81579/1573	PLA2G12A/CYP2J2	2
hsa05016	Huntington's disease	12/409	183/5868	0.631150188733507	0.999999999999755	5468/161/23186/291/7052/1537/51164/1213/7019/1337/64764/10488	PPARG/AP2A2/RCOR1/SLC25A4/TGM2/CYC1/DCTN4/CLTC/TFAM/COX6A1/CREB3L2/CREB3	12
hsa04975	Fat digestion and absorption	3/409	46/5868	0.631437102930452	0.999999999999755	8613/10554/81579	PLPP3/AGPAT1/PLA2G12A	3
hsa00520	Amino sugar and nucleotide sugar metabolism	3/409	48/5868	0.660306313431234	0.999999999999755	51706/2673/5373	CYB5R1/GFPT1/PMM2	3
hsa04140	Regulation of autophagy	2/409	34/5868	0.696711792529678	0.999999999999755	23710/84938	GABARAPL1/ATG4C	2
hsa05020	Prion diseases	2/409	35/5868	0.711968987679155	0.999999999999755	3915/6352	LAMC1/CCL5	2
hsa00983	Drug metabolism - other enzymes	3/409	52/5868	0.713050114469052	0.999999999999755	7083/3615/2990	TK1/IMPDH2/GUSB	3
hsa04150	mTOR signaling pathway	3/409	52/5868	0.713050114469052	0.999999999999755	253260/5228/5170	RICTOR/PGF/PDPK1	3
hsa04912	GnRH signaling pathway	6/409	101/5868	0.715864650136144	0.999999999999755	1956/4323/818/2767/3265/81579	EGFR/MMP14/CAMK2G/GNA11/HRAS/PLA2G12A	6
hsa00051	Fructose and mannose metabolism	2/409	36/5868	0.726579035635696	0.999999999999755	5373/231	PMM2/AKR1B1	2
hsa03030	DNA replication	2/409	36/5868	0.726579035635696	0.999999999999755	4171/2237	MCM2/FEN1	2
hsa00630	Glyoxylate and dicarboxylate metabolism	1/409	18/5868	0.728128514735982	0.999999999999755	48	ACO1	1
hsa00670	One carbon pool by folate	1/409	18/5868	0.728128514735982	0.999999999999755	471	ATIC	1
hsa00500	Starch and sucrose metabolism	3/409	54/5868	0.73695408335847	0.999999999999755	2548/178/2990	GAA/AGL/GUSB	3
hsa00980	Metabolism of xenobiotics by cytochrome P450	4/409	71/5868	0.739438080517824	0.999999999999755	4259/2954/2950/2941	MGST3/GSTZ1/GSTP1/GSTA4	4
hsa04650	Natural killer cell mediated cytotoxicity	8/409	136/5868	0.741535323087503	0.999999999999755	3106/3105/3265/3107/10725/3133/10451/10870	HLA-B/HLA-A/HRAS/HLA-C/NFAT5/HLA-E/VAV3/HCST	8
hsa04910	Insulin signaling pathway	8/409	138/5868	0.75605837355841	0.999999999999755	10580/3265/5584/5792/8660/2319/572/5170	SORBS1/HRAS/PRKCI/PTPRF/IRS2/FLOT2/BAD/PDPK1	8
hsa00982	Drug metabolism - cytochrome P450	4/409	73/5868	0.759049834012383	0.999999999999755	4259/2954/2950/2941	MGST3/GSTZ1/GSTP1/GSTA4	4
hsa00140	Steroid hormone biosynthesis	3/409	56/5868	0.759258221854201	0.999999999999755	3292/1312/51144	HSD17B1/COMT/HSD17B12	3
hsa04340	Hedgehog signaling pathway	3/409	56/5868	0.759258221854201	0.999999999999755	4036/655/2737	LRP2/BMP7/GLI3	3
hsa04630	Jak-STAT signaling pathway	9/409	155/5868	0.763062887433798	0.999999999999755	3977/5618/1441/1438/3572/30837/3588/595/3561	LIFR/PRLR/CSF3R/CSF2RA/IL6ST/SOCS7/IL10RB/CCND1/IL2RG	9
hsa00592	alpha-Linolenic acid metabolism	1/409	20/5868	0.76481815235597	0.999999999999755	81579	PLA2G12A	1
hsa04660	T cell receptor signaling pathway	6/409	108/5868	0.773952347248618	0.999999999999755	56924/3265/10725/6885/10451/8915	PAK6/HRAS/NFAT5/MAP3K7/VAV3/BCL10	6
hsa04662	B cell receptor signaling pathway	4/409	75/5868	0.777501868376374	0.999999999999755	3265/10725/10451/8915	HRAS/NFAT5/VAV3/BCL10	4
hsa01040	Biosynthesis of unsaturated fatty acids	1/409	21/5868	0.781266404012333	0.999999999999755	51144	HSD17B12	1
hsa00590	Arachidonic acid metabolism	3/409	59/5868	0.789824166406211	0.999999999999755	9536/81579/1573	PTGES/PLA2G12A/CYP2J2	3
hsa04722	Neurotrophin signaling pathway	7/409	127/5868	0.792158534760777	0.999999999999755	9500/2549/818/3265/8660/8986/572	MAGED1/GAB1/CAMK2G/HRAS/IRS2/RPS6KA4/BAD	7
hsa04710	Circadian rhythm	1/409	22/5868	0.796566906964095	0.999999999999755	79365	BHLHE41	1
hsa04960	Aldosterone-regulated sodium reabsorption	2/409	42/5868	0.801591465185823	0.999999999999755	8660/5170	IRS2/PDPK1	2
hsa00230	Purine metabolism	9/409	162/5868	0.806276443082113	0.999999999999755	158/4833/5471/3615/5150/132/4830/471/6240	ADSL/NME4/PPAT/IMPDH2/PDE7A/ADK/NME1/ATIC/RRM1	9
hsa03060	Protein export	1/409	23/5868	0.810799567766642	0.999999999999755	11231	SEC63	1
hsa03008	Ribosome biogenesis in eukaryotes	4/409	79/5868	0.811044353135432	0.999999999999755	23160/55341/55127/10199	WDR43/LSG1/HEATR1/MPHOSPH10	4
hsa02010	ABC transporters	2/409	44/5868	0.822213522353162	0.999999999999755	9429/11194	ABCG2/ABCB8	2
hsa03420	Nucleotide excision repair	2/409	44/5868	0.822213522353162	0.999999999999755	1642/5887	DDB1/RAD23B	2
hsa00760	Nicotinate and nicotinamide metabolism	1/409	24/5868	0.824038742579891	0.999999999999755	23475	QPRT	1
hsa04270	Vascular smooth muscle contraction	6/409	116/5868	0.828930742009361	0.999999999999755	2768/2767/800/4660/81579/9826	GNA12/GNA11/CALD1/PPP1R12B/PLA2G12A/ARHGEF11	6
hsa04060	Cytokine-cytokine receptor interaction	15/409	265/5868	0.836536412720639	0.999999999999755	3977/1956/4233/5618/655/1441/1438/3572/93/27242/2321/3588/6352/5154/3561	LIFR/EGFR/MET/PRLR/BMP7/CSF3R/CSF2RA/IL6ST/ACVR2B/TNFRSF21/FLT1/IL10RB/CCL5/PDGFA/IL2RG	15
hsa03015	mRNA surveillance pathway	4/409	83/5868	0.840347947214355	0.999999999999755	124540/5516/65110/1477	MSI2/PPP2CB/UPF3A/CSTF1	4
hsa00010	Glycolysis / Gluconeogenesis	3/409	65/5868	0.841318509665363	0.999999999999755	84532/501/3945	ACSS1/ALDH7A1/LDHB	3
hsa00053	Ascorbate and aldarate metabolism	1/409	26/5868	0.847808588220968	0.999999999999755	501	ALDH7A1	1
hsa04920	Adipocytokine signaling pathway	3/409	68/5868	0.862716005295739	0.999999999999755	6513/6256/8660	SLC2A1/RXRA/IRS2	3
hsa04610	Complement and coagulation cascades	3/409	69/5868	0.869264682216804	0.999999999999755	2153/4179/966	F5/CD46/CD59	3
hsa05144	Malaria	2/409	51/5868	0.880058304316922	0.999999999999755	4233/4035	MET/LRP1	2
hsa00650	Butanoate metabolism	1/409	30/5868	0.886166742713632	0.999999999999755	35	ACADS	1
hsa05140	Leishmaniasis	3/409	72/5868	0.887286696553378	0.999999999999755	6885/1535/3688	MAP3K7/CYBA/ITGB1	3
hsa05014	Amyotrophic lateral sclerosis (ALS)	2/409	53/5868	0.893073294847715	0.999999999999755	57679/572	ALS2/BAD	2
hsa04971	Gastric acid secretion	3/409	74/5868	0.898037351953029	0.999999999999755	6522/2770/818	SLC4A2/GNAI1/CAMK2G	3
hsa04062	Chemokine signaling pathway	9/409	189/5868	0.919161484207856	0.999999999999755	2770/55970/3265/56288/8976/5747/6352/10451/2787	GNAI1/GNG12/HRAS/PARD3/WASL/PTK2/CCL5/VAV3/GNG5	9
hsa05340	Primary immunodeficiency	1/409	35/5868	0.920842540940193	0.999999999999755	3561	IL2RG	1
hsa04664	Fc epsilon RI signaling pathway	3/409	79/5868	0.92099052955344	0.999999999999755	3265/81579/10451	HRAS/PLA2G12A/VAV3	3
hsa03022	Basal transcription factors	1/409	36/5868	0.926392926806036	0.999999999999755	6882	TAF11	1
hsa05142	Chagas disease (American trypanosomiasis)	4/409	104/5868	0.938642589193972	0.999999999999755	2770/2767/6352/5516	GNAI1/GNA11/CCL5/PPP2CB	4
hsa04914	Progesterone-mediated oocyte maturation	3/409	86/5868	0.945249822420628	0.999999999999755	2770/3480/890	GNAI1/IGF1R/CCNA2	3
hsa05010	Alzheimer's disease	7/409	167/5868	0.952412360277928	0.999999999999755	4035/351/4311/1537/1337/572/25825	LRP1/APP/MME/CYC1/COX6A1/BAD/BACE2	7
hsa00380	Tryptophan metabolism	1/409	42/5868	0.952426206336378	0.999999999999755	501	ALDH7A1	1
hsa04114	Oocyte meiosis	4/409	112/5868	0.958497293196073	0.999999999999755	818/3480/5516/898	CAMK2G/IGF1R/PPP2CB/CCNE1	4
hsa00190	Oxidative phosphorylation	5/409	132/5868	0.958524483807772	0.999999999999755	525/1537/51606/1337/245973	ATP6V1B1/CYC1/ATP6V1H/COX6A1/ATP6V1C2	5
hsa04720	Long-term potentiation	2/409	70/5868	0.961072832739815	0.999999999999755	818/3265	CAMK2G/HRAS	2
hsa04622	RIG-I-like receptor signaling pathway	2/409	71/5868	0.963378102704852	0.999999999999755	6885/8653	MAP3K7/DDX3Y	2
hsa00514	Other types of O-glycan biosynthesis	1/409	46/5868	0.964446085648276	0.999999999999755	283464	GXYLT1	1
hsa04020	Calcium signaling pathway	7/409	177/5868	0.968664241044074	0.999999999999755	1956/153/818/2767/2065/490/291	EGFR/ADRB1/CAMK2G/GNA11/ERBB3/ATP2B1/SLC25A4	7
hsa04930	Type II diabetes mellitus	1/409	48/5868	0.969266399864821	0.999999999999755	8660	IRS2	1
hsa04260	Cardiac muscle contraction	2/409	77/5868	0.974688550499463	0.999999999999755	1537/1337	CYC1/COX6A1	2
hsa04972	Pancreatic secretion	3/409	101/5868	0.975851345745946	0.999999999999755	6522/490/81579	SLC4A2/ATP2B1/PLA2G12A	3
hsa04623	Cytosolic DNA-sensing pathway	1/409	56/5868	0.982848908667084	0.999999999999755	6352	CCL5	1
hsa05012	Parkinson's disease	4/409	130/5868	0.983504301635134	0.999999999999755	291/1537/65018/1337	SLC25A4/CYC1/PINK1/COX6A1	4
hsa04210	Apoptosis	2/409	87/5868	0.986468597417913	0.999999999999755	572/1676	BAD/DFFA	2
hsa03010	Ribosome	2/409	91/5868	0.989501342468561	0.999999999999755	6192/6134	RPS4Y1/RPL10	2
hsa00830	Retinol metabolism	1/409	64/5868	0.990436692251208	0.999999999999755	157506	RDH10	1
hsa03040	Spliceosome	3/409	127/5868	0.994616395643239	0.999999999999755	9716/10713/1665	AQR/USP39/DHX15	3
hsa03013	RNA transport	4/409	151/5868	0.99471615747074	0.999999999999755	9086/9972/5903/65110	EIF1AY/NUP153/RANBP2/UPF3A	4
hsa04620	Toll-like receptor signaling pathway	2/409	102/5868	0.994818769909435	0.999999999999755	6885/6352	MAP3K7/CCL5	2
hsa04380	Osteoclast differentiation	3/409	128/5868	0.994926988160069	0.999999999999755	5468/6885/1535	PPARG/MAP3K7/CYBA	3
hsa05322	Systemic lupus erythematosus	1/409	136/5868	0.999952027183968	0.999999999999755	87	ACTN1	1
hsa04080	Neuroactive ligand-receptor interaction	5/409	272/5868	0.999981421936811	0.999999999999755	5618/153/2564/56288/5031	PRLR/ADRB1/GABRE/PARD3/P2RY6	5
hsa04740	Olfactory transduction	1/409	388/5868	0.999999999999755	0.999999999999755	818	CAMK2G	1