ID Description GeneRatio BgRatio pvalue p.adjust geneID geneName Count hsa04510 Focal adhesion 12/86 200/5868 2.94072996298353e-05 0.0029995445622432 3911/5063/4233/9564/1284/3675/55742/3691/3696/3685/5747/5170 LAMA5/PAK3/MET/BCAR1/COL4A2/ITGA3/PARVA/ITGB4/ITGB8/ITGAV/PTK2/PDPK1 12 hsa04512 ECM-receptor interaction 6/86 85/5868 0.0014411747384115 0.0489999411059912 3911/1284/3675/3691/3696/3685 LAMA5/COL4A2/ITGA3/ITGB4/ITGB8/ITGAV 6 hsa05222 Small cell lung cancer 6/86 85/5868 0.0014411747384115 0.0489999411059912 3911/1284/3675/3685/5747/10401 LAMA5/COL4A2/ITGA3/ITGAV/PTK2/PIAS3 6 hsa00531 Glycosaminoglycan degradation 3/86 19/5868 0.00248573677031413 0.0546858835668922 4669/2588/2799 NAGLU/GALNS/GNS 3 hsa04360 Axon guidance 7/86 129/5868 0.00268068056700452 0.0546858835668922 1946/57715/5063/4233/9901/23365/5747 EFNA5/SEMA4G/PAK3/MET/SRGAP3/ARHGEF12/PTK2 7 hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 5/86 74/5868 0.00438461744747885 0.0717668405825096 2697/3675/3691/3696/3685 GJA1/ITGA3/ITGB4/ITGB8/ITGAV 5 hsa04977 Vitamin digestion and absorption 3/86 24/5868 0.00492517533409379 0.0717668405825096 151056/10560/6573 PLB1/SLC19A2/SLC19A1 3 hsa05410 Hypertrophic cardiomyopathy (HCM) 5/86 83/5868 0.0071329371487885 0.0909449486470534 3675/3691/3696/3685/5564 ITGA3/ITGB4/ITGB8/ITGAV/PRKAB1 5 hsa04142 Lysosome 6/86 121/5868 0.00833726917101413 0.0944890506048268 4669/4126/1203/8722/2588/2799 NAGLU/MANBA/CLN5/CTSF/GALNS/GNS 6 hsa04810 Regulation of actin cytoskeleton 8/86 213/5868 0.0123386053230267 0.120055035499574 5063/9564/3675/3691/23365/3696/3685/5747 PAK3/BCAR1/ITGA3/ITGB4/ARHGEF12/ITGB8/ITGAV/PTK2 8 hsa04514 Cell adhesion molecules (CAMs) 6/86 133/5868 0.0129471116715227 0.120055035499574 9369/149461/83700/3696/3685/5797 NRXN3/CLDN19/JAM3/ITGB8/ITGAV/PTPRM 6 hsa05100 Bacterial invasion of epithelial cells 4/86 70/5868 0.0189419998218956 0.161006998486113 4233/9564/5747/10059 MET/BCAR1/PTK2/DNM1L 4 hsa04670 Leukocyte transendothelial migration 5/86 116/5868 0.0271204801369971 0.212791459536439 149461/83700/9564/1500/5747 CLDN19/JAM3/BCAR1/CTNND1/PTK2 5 hsa00564 Glycerophospholipid metabolism 4/86 80/5868 0.029286262661229 0.213371342246097 151056/8613/23761/81490 PLB1/PLPP3/PISD/PTDSS2 4 hsa05414 Dilated cardiomyopathy 4/86 90/5868 0.0424308595598274 0.288529845006827 3675/3691/3696/3685 ITGA3/ITGB4/ITGB8/ITGAV 4 hsa04340 Hedgehog signaling pathway 3/86 56/5868 0.0483155260960202 0.308011478862129 2737/4036/51715 GLI3/LRP2/RAB23 3 hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series 2/86 26/5868 0.0549771554331907 0.329862932599144 10402/10331 ST3GAL6/B3GNT3 2 hsa04920 Adipocytokine signaling pathway 3/86 68/5868 0.0772253584713274 0.414578240214494 3667/2180/5564 IRS1/ACSL1/PRKAB1 3 hsa05120 Epithelial cell signaling in Helicobacter pylori infection 3/86 68/5868 0.0772253584713274 0.414578240214494 3579/4233/83700 CXCR2/MET/JAM3 3 hsa03320 PPAR signaling pathway 3/86 70/5868 0.0826449733457624 0.421489364063388 10062/2180/5170 NR1H3/ACSL1/PDPK1 3 hsa04520 Adherens junction 3/86 73/5868 0.0910734106113398 0.442356565826508 4233/1500/5797 MET/CTNND1/PTPRM 3 hsa00565 Ether lipid metabolism 2/86 36/5868 0.0971212302986678 0.450289340475642 151056/8613 PLB1/PLPP3 2 hsa05200 Pathways in cancer 8/86 326/5868 0.103570303574643 0.459311781070155 3911/4233/2737/1284/3675/3685/5747/10401 LAMA5/MET/GLI3/COL4A2/ITGA3/ITGAV/PTK2/PIAS3 8 hsa04350 TGF-beta signaling pathway 3/86 84/5868 0.1247988938536 0.480240463085061 4052/659/6667 LTBP1/BMPR2/SP1 3 hsa04960 Aldosterone-regulated sodium reabsorption 2/86 42/5868 0.125607729292315 0.480240463085061 3667/5170 IRS1/PDPK1 2 hsa00071 Fatty acid degradation 2/86 43/5868 0.13053437761953 0.480240463085061 35/2180 ACADS/ACSL1 2 hsa05160 Hepatitis C 4/86 134/5868 0.13288662569634 0.480240463085061 7098/10062/149461/10401 TLR3/NR1H3/CLDN19/PIAS3 4 hsa04012 ErbB signaling pathway 3/86 87/5868 0.134691104424494 0.480240463085061 685/5063/5747 BTC/PAK3/PTK2 3 hsa04122 Sulfur relay system 1/86 10/5868 0.137358731143889 0.480240463085061 4337 MOCS1 1 hsa04975 Fat digestion and absorption 2/86 46/5868 0.145572476255941 0.480240463085061 8613/19 PLPP3/ABCA1 2 hsa00790 Folate biosynthesis 1/86 11/5868 0.150022976470216 0.480240463085061 6697 SPR 1 hsa04330 Notch signaling pathway 2/86 47/5868 0.150663674693352 0.480240463085061 4854/5664 NOTCH3/PSEN2 2 hsa04144 Endocytosis 5/86 201/5868 0.171304572185044 0.529486859481046 30845/3579/4233/22905/10059 EHD3/CXCR2/MET/EPN2/DNM1L 5 hsa00603 Glycosphingolipid biosynthesis - globo series 1/86 14/5868 0.18692347754054 0.560770432621619 26301 GBGT1 1 hsa05146 Amoebiasis 3/86 106/5868 0.20275924743202 0.590898378230458 3911/1284/5747 LAMA5/COL4A2/PTK2 3 hsa00450 Selenocompound metabolism 1/86 17/5868 0.222239823072669 0.596538472458218 10587 TXNRD2 1 hsa00511 Other glycan degradation 1/86 17/5868 0.222239823072669 0.596538472458218 4126 MANBA 1 hsa04614 Renin-angiotensin system 1/86 17/5868 0.222239823072669 0.596538472458218 2028 ENPEP 1 hsa04270 Vascular smooth muscle contraction 3/86 116/5868 0.241354513179693 0.622109398877476 94274/23365/4660 PPP1R14A/ARHGEF12/PPP1R12B 3 hsa00592 alpha-Linolenic acid metabolism 1/86 20/5868 0.256039255566868 0.622109398877476 151056 PLB1 1 hsa04610 Complement and coagulation cascades 2/86 69/5868 0.268391143595201 0.622109398877476 5054/2153 SERPINE1/F5 2 hsa05211 Renal cell carcinoma 2/86 70/5868 0.273854266249596 0.622109398877476 5063/4233 PAK3/MET 2 hsa00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 1/86 22/5868 0.277761406398678 0.622109398877476 9469 CHST3 1 hsa04710 Circadian rhythm 1/86 22/5868 0.277761406398678 0.622109398877476 79365 BHLHE41 1 hsa04976 Bile secretion 2/86 71/5868 0.279316269137411 0.622109398877476 6522/760 SLC4A2/CA2 2 hsa00910 Nitrogen metabolism 1/86 23/5868 0.28838619583585 0.622109398877476 760 CA2 1 hsa04964 Proximal tubule bicarbonate reclamation 1/86 23/5868 0.28838619583585 0.622109398877476 760 CA2 1 hsa04971 Gastric acid secretion 2/86 74/5868 0.295684440394483 0.622109398877476 6522/760 SLC4A2/CA2 2 hsa04320 Dorso-ventral axis formation 1/86 24/5868 0.298856475931337 0.622109398877476 4854 NOTCH3 1 hsa04530 Tight junction 3/86 132/5868 0.305219921164596 0.622648639175775 149461/83700/8189 CLDN19/JAM3/SYMPK 3 hsa04146 Peroxisome 2/86 79/5868 0.322843272654917 0.630212863298996 3417/2180 IDH1/ACSL1 2 hsa04966 Collecting duct acid secretion 1/86 27/5868 0.329362311607538 0.630212863298996 760 CA2 1 hsa04910 Insulin signaling pathway 3/86 138/5868 0.329465512469911 0.630212863298996 3667/5170/5564 IRS1/PDPK1/PRKAB1 3 hsa04974 Protein digestion and absorption 2/86 81/5868 0.333642104099469 0.630212863298996 7373/1284 COL14A1/COL4A2 2 hsa00020 Citrate cycle (TCA cycle) 1/86 30/5868 0.358555645540184 0.630563376639634 3417 IDH1 1 hsa00512 Mucin type O-Glycan biosynthesis 1/86 30/5868 0.358555645540184 0.630563376639634 2591 GALNT3 1 hsa00591 Linoleic acid metabolism 1/86 30/5868 0.358555645540184 0.630563376639634 151056 PLB1 1 hsa00650 Butanoate metabolism 1/86 30/5868 0.358555645540184 0.630563376639634 35 ACADS 1 hsa04140 Regulation of autophagy 1/86 34/5868 0.395534584309274 0.683805552534677 10533 ATG7 1 hsa04666 Fc gamma R-mediated phagocytosis 2/86 94/5868 0.402415737515313 0.684106753776032 8613/10059 PLPP3/DNM1L 2 hsa00240 Pyrimidine metabolism 2/86 99/5868 0.42801807732294 0.715702358802294 10587/56474 TXNRD2/CTPS2 2 hsa04972 Pancreatic secretion 2/86 101/5868 0.438102130560118 0.720748666405356 6522/760 SLC4A2/CA2 2 hsa00600 Sphingolipid metabolism 1/86 40/5868 0.447087066808007 0.723855251022488 8613 PLPP3 1 hsa00280 Valine, leucine and isoleucine degradation 1/86 44/5868 0.479015707531142 0.741406647826919 35 ACADS 1 hsa02010 ABC transporters 1/86 44/5868 0.479015707531142 0.741406647826919 19 ABCA1 1 hsa04930 Type II diabetes mellitus 1/86 48/5868 0.509120798443634 0.741406647826919 3667 IRS1 1 hsa00480 Glutathione metabolism 1/86 50/5868 0.523521926568763 0.741406647826919 3417 IDH1 1 hsa00561 Glycerolipid metabolism 1/86 50/5868 0.523521926568763 0.741406647826919 8613 PLPP3 1 hsa04062 Chemokine signaling pathway 3/86 189/5868 0.527714170345049 0.741406647826919 3579/9564/5747 CXCR2/BCAR1/PTK2 3 hsa05144 Malaria 1/86 51/5868 0.530565088190469 0.741406647826919 4233 MET 1 hsa04150 mTOR signaling pathway 1/86 52/5868 0.537505332717823 0.741406647826919 5170 PDPK1 1 hsa05213 Endometrial cancer 1/86 52/5868 0.537505332717823 0.741406647826919 5170 PDPK1 1 hsa04060 Cytokine-cytokine receptor interaction 4/86 265/5868 0.548883275622717 0.741406647826919 3579/4233/3977/659 CXCR2/MET/LIFR/BMPR2 4 hsa05110 Vibrio cholerae infection 1/86 54/5868 0.551082994964954 0.741406647826919 11015 KDELR3 1 hsa05223 Non-small cell lung cancer 1/86 54/5868 0.551082994964954 0.741406647826919 5170 PDPK1 1 hsa05217 Basal cell carcinoma 1/86 55/5868 0.557723322180815 0.741406647826919 2737 GLI3 1 hsa04722 Neurotrophin signaling pathway 2/86 127/5868 0.559689332183066 0.741406647826919 3667/5664 IRS1/PSEN2 2 hsa00590 Arachidonic acid metabolism 1/86 59/5868 0.583327589390373 0.762813001510487 151056 PLB1 1 hsa00970 Aminoacyl-tRNA biosynthesis 1/86 63/5868 0.60746581961903 0.784322956976469 51067 YARS2 1 hsa04115 p53 signaling pathway 1/86 68/5868 0.635703007628105 0.810521334725833 5054 SERPINE1 1 hsa05218 Melanoma 1/86 71/5868 0.651671562812057 0.820623449467035 4233 MET 1 hsa04630 Jak-STAT signaling pathway 2/86 155/5868 0.668716061224939 0.831683849842605 3977/10401 LIFR/PIAS3 2 hsa04370 VEGF signaling pathway 1/86 76/5868 0.676762348401336 0.831683849842605 5747 PTK2 1 hsa04141 Protein processing in endoplasmic reticulum 2/86 165/5868 0.702082912500814 0.845685277727298 23640/6238 HSPBP1/RRBP1 2 hsa03015 mRNA surveillance pathway 1/86 83/5868 0.708914420084285 0.845685277727298 8189 SYMPK 1 hsa04640 Hematopoietic cell lineage 1/86 88/5868 0.729924104199399 0.845685277727298 3675 ITGA3 1 hsa04970 Salivary secretion 1/86 89/5868 0.733942534482937 0.845685277727298 6522 SLC4A2 1 hsa05215 Prostate cancer 1/86 89/5868 0.733942534482937 0.845685277727298 5170 PDPK1 1 hsa04540 Gap junction 1/86 90/5868 0.737901859977741 0.845685277727298 2697 GJA1 1 hsa04620 Toll-like receptor signaling pathway 1/86 102/5868 0.781104348911157 0.88278856583696 7098 TLR3 1 hsa05142 Chagas disease (American trypanosomiasis) 1/86 104/5868 0.787585877364347 0.88278856583696 5054 SERPINE1 1 hsa04660 T cell receptor signaling pathway 1/86 108/5868 0.799985167797794 0.886940077341032 5063 PAK3 1 hsa04110 Cell cycle 1/86 124/5868 0.842821048942505 0.924384376259521 7465 WEE1 1 hsa05145 Toxoplasmosis 1/86 132/5868 0.860700269990032 0.930748317871476 3911 LAMA5 1 hsa04120 Ubiquitin mediated proteolysis 1/86 135/5868 0.866873433311669 0.930748317871476 10401 PIAS3 1 hsa03013 RNA transport 1/86 151/5868 0.895504022149051 0.935749471339683 11260 XPOT 1 hsa04145 Phagosome 1/86 153/5868 0.898624482495669 0.935749471339683 3685 ITGAV 1 hsa00230 Purine metabolism 1/86 162/5868 0.911564553780933 0.935749471339683 10846 PDE10A 1 hsa04080 Neuroactive ligand-receptor interaction 2/86 272/5868 0.914145025127918 0.935749471339683 2564/5027 GABRE/P2RX7 2 hsa05010 Alzheimer's disease 1/86 167/5868 0.918033298320564 0.935749471339683 5664 PSEN2 1 hsa04020 Calcium signaling pathway 1/86 177/5868 0.92960009187567 0.935749471339683 5027 P2RX7 1 hsa05016 Huntington's disease 1/86 183/5868 0.935749471339683 0.935749471339683 6667 SP1 1