ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0002181 cytoplasmic translation 43/742 148/18722 1.22737047807475e-25 6.06321016168927e-22 RPS21/RPLP0/RPS20/RPL13A/RPL23A/RPS3A/RPS13/RPS11/RPL27A/RPS10/RPS6/RPS16/RPL31/RPL6/RPL14/EIF3A/RPL7/RPL21/RPS25/RPL24/RPL19/RPL13/RPL18A/RPL9/RPL15/RPS26/UBA52/RPL26/RPL23/RPS2/RPL4/RPL3/EIF4G1/RPL17/RPS17/EIF3H/DHX36/PKM/EIF2S2/EIF3F/EIF4H/EIF3I/EIF4B 43 GO:0001667 ameboidal-type cell migration 54/742 475/18722 3.12452013489276e-12 7.71756473318511e-09 ITGB4/NRP2/GRN/LAMA5/ITGB1/SEMA6A/RHOB/MET/SERPINF1/MACF1/PLEC/KANK1/EPHB4/SEMA6D/GJA1/PLPP3/S100P/DPP4/PKN2/RTN4/LRP5/NRP1/BMP7/TACSTD2/ATP2B4/ISL1/FERMT1/NR2F2/CALR/MIA3/FOLR1/PFN1/TMSB4X/ANXA1/FSTL1/LGMN/NF1/WASF2/ROCK1/EMC10/TPBG/FOXP1/ARID5B/GNA12/GATA3/MARVELD3/HSPB1/GPX1/ID1/CLN3/RHOA/RAB11A/ANXA3/CSNK2B 54 GO:0016032 viral process 48/742 415/18722 2.84942694549614e-11 4.69205637025032e-08 JUN/EGFR/CD46/CTSL/ITGAV/ITGB1/DAG1/P4HB/EIF3A/BSG/TFRC/CAV1/SLC3A2/SLC1A5/HACD3/SLC52A1/DPP4/PKN2/EEA1/NRP1/MPHOSPH8/HSPA1A/CD81/DDB1/ITGB5/CANX/MAN2A1/STOM/HSPA1B/CD55/MOGS/CFL1/PPIA/FUT8/LAMP1/RSF1/EIF2AK4/LARP1/SLC52A2/PCBP2/DDX5/ADAR/RAN/CDC42/EIF3F/SSB/DYNLT1/BANF1 48 GO:0061458 reproductive system development 46/742 427/18722 7.90617646642762e-10 9.76412793603811e-07 LRP2/SPINT1/HSPA5/ADGRG1/KRT19/PSAP/RPS6/SPINT2/SERPINF1/SF1/BSG/BPTF/ATRX/LGR4/DHCR24/GJA1/ADAMTS1/CTSV/ZFP36L1/KRT8/BMP7/NR2F2/MME/ANXA1/GLI3/ASH1L/JUNB/KDM5A/DLG1/NIPBL/ST14/HECTD1/ADM/ARID5B/KDM5B/PLEKHA5/CITED2/GATA3/EPAS1/RHOBTB3/PRDX4/HES1/EIF2S2/IGF2/CYP19A1/CGA 46 GO:0048732 gland development 46/742 436/18722 1.55324055491158e-09 1.53460166825264e-06 EGFR/CDH1/LAMA5/DAG1/PSAP/RPS16/MET/SERPINF1/WLS/RPL19/CAV1/TGFBR3/PBX1/PRKDC/LSR/RTN4/LRP5/NRP1/BMP7/LMO4/ISL1/PRLR/SRSF5/ANXA1/GLI3/NF1/UPF2/ASH1L/MAN2A1/SEC63/RB1CC1/ARID5B/PRKCSH/KDM5B/ARHGAP5/CITED2/KRT18/GATA3/GPX1/HES1/CDC42/TGM2/IGF2/CSNK2B/LBH/CGA 46 GO:0048608 reproductive structure development 45/742 424/18722 1.94782836816498e-09 1.6037120231225e-06 LRP2/SPINT1/HSPA5/ADGRG1/KRT19/PSAP/RPS6/SPINT2/SERPINF1/SF1/BSG/BPTF/ATRX/LGR4/DHCR24/GJA1/ADAMTS1/CTSV/ZFP36L1/KRT8/BMP7/NR2F2/MME/ANXA1/GLI3/ASH1L/JUNB/KDM5A/DLG1/NIPBL/ST14/HECTD1/ADM/ARID5B/KDM5B/CITED2/GATA3/EPAS1/RHOBTB3/PRDX4/HES1/EIF2S2/IGF2/CYP19A1/CGA 45 GO:0019058 viral life cycle 37/742 317/18722 4.30158678007878e-09 3.03569124194131e-06 EGFR/CD46/CTSL/ITGAV/ITGB1/DAG1/P4HB/BSG/TFRC/CAV1/SLC3A2/SLC1A5/HACD3/SLC52A1/DPP4/PKN2/EEA1/NRP1/MPHOSPH8/HSPA1A/CD81/DDB1/ITGB5/STOM/HSPA1B/CD55/PPIA/LAMP1/EIF2AK4/LARP1/SLC52A2/PCBP2/DDX5/ADAR/CDC42/DYNLT1/BANF1 37 GO:0010631 epithelial cell migration 39/742 357/18722 1.06658707931718e-08 6.37588225449022e-06 NRP2/GRN/ITGB1/RHOB/MET/SERPINF1/MACF1/KANK1/EPHB4/PLPP3/S100P/DPP4/PKN2/RTN4/NRP1/TACSTD2/ATP2B4/FERMT1/NR2F2/CALR/MIA3/PFN1/TMSB4X/ANXA1/FSTL1/LGMN/NF1/ROCK1/EMC10/FOXP1/GATA3/MARVELD3/HSPB1/GPX1/ID1/RHOA/RAB11A/ANXA3/CSNK2B 39 GO:0046718 viral entry into host cell 23/742 144/18722 1.16159798158729e-08 6.37588225449022e-06 EGFR/CD46/CTSL/ITGAV/ITGB1/DAG1/P4HB/BSG/TFRC/CAV1/SLC3A2/SLC1A5/SLC52A1/DPP4/NRP1/HSPA1A/CD81/ITGB5/HSPA1B/CD55/LAMP1/SLC52A2/DYNLT1 23 GO:0090132 epithelium migration 39/742 360/18722 1.34537330065059e-08 6.6461441052139e-06 NRP2/GRN/ITGB1/RHOB/MET/SERPINF1/MACF1/KANK1/EPHB4/PLPP3/S100P/DPP4/PKN2/RTN4/NRP1/TACSTD2/ATP2B4/FERMT1/NR2F2/CALR/MIA3/PFN1/TMSB4X/ANXA1/FSTL1/LGMN/NF1/ROCK1/EMC10/FOXP1/GATA3/MARVELD3/HSPB1/GPX1/ID1/RHOA/RAB11A/ANXA3/CSNK2B 39 GO:0090130 tissue migration 39/742 365/18722 1.96792018644223e-08 8.15315542392632e-06 NRP2/GRN/ITGB1/RHOB/MET/SERPINF1/MACF1/KANK1/EPHB4/PLPP3/S100P/DPP4/PKN2/RTN4/NRP1/TACSTD2/ATP2B4/FERMT1/NR2F2/CALR/MIA3/PFN1/TMSB4X/ANXA1/FSTL1/LGMN/NF1/ROCK1/EMC10/FOXP1/GATA3/MARVELD3/HSPB1/GPX1/ID1/RHOA/RAB11A/ANXA3/CSNK2B 39 GO:0043484 regulation of RNA splicing 23/742 148/18722 1.98052358475943e-08 8.15315542392632e-06 AHNAK/SON/RPS13/SF1/FUS/RBM39/RPS26/SLC38A2/NPM1/RBM25/SRSF5/HSPA1A/TRA2B/HNRNPA1/DDX17/SRSF7/POLR2A/SRSF6/CELF1/CIRBP/PRDX6/DDX5/MBNL3 23 GO:0006457 protein folding 28/742 212/18722 2.35169043071773e-08 8.93642363672736e-06 HSP90B1/HSPA5/GRN/LMAN1/P4HB/PDIA3/ERP29/NKTR/SIL1/PDIA4/CCDC47/CALR/HSPA1A/CANX/P3H1/PPIG/RANBP2/HSPA1B/DNAJB14/MOGS/ATF6/PPIA/PDIA6/HSPB1/DNAJB1/PRDX4/PTGES3/CCT3 28 GO:0052126 movement in host environment 25/742 175/18722 2.74980726915324e-08 9.60638542281111e-06 EGFR/CD46/CTSL/ITGAV/ITGB1/DAG1/P4HB/BSG/TFRC/CAV1/SLC3A2/SLC1A5/SLC52A1/DPP4/NRP1/HSPA1A/CD81/DDB1/ITGB5/HSPA1B/CD55/PPIA/LAMP1/SLC52A2/DYNLT1 25 GO:0044409 entry into host 23/742 151/18722 2.91691865065115e-08 9.60638542281111e-06 EGFR/CD46/CTSL/ITGAV/ITGB1/DAG1/P4HB/BSG/TFRC/CAV1/SLC3A2/SLC1A5/SLC52A1/DPP4/NRP1/HSPA1A/CD81/ITGB5/HSPA1B/CD55/LAMP1/SLC52A2/DYNLT1 23 GO:0051701 biological process involved in interaction with host 27/742 203/18722 3.60161056662126e-08 1.11199726244431e-05 EGFR/CD46/CTSL/ITGAV/ITGB1/DAG1/P4HB/BSG/TFRC/CAV1/SLC3A2/SLC1A5/SLC52A1/DPP4/NRP1/HSPA1A/CD81/DDB1/ITGB5/HSPA1B/CD55/PPIA/THOC2/LAMP1/SLC52A2/SERPINB9/DYNLT1 27 GO:0044403 biological process involved in symbiotic interaction 33/742 290/18722 5.48804727052713e-08 1.51059294036393e-05 JUN/EGFR/GAPDH/CD46/CTSL/ITGAV/ITGB1/DAG1/P4HB/BSG/TFRC/CAV1/SLC3A2/SLC1A5/SLC52A1/DPP4/NRP1/HSPA1A/CD81/DDB1/ITGB5/STOM/HSPA1B/CD55/CFL1/PPIA/THOC2/LAMP1/EIF2AK4/SLC52A2/GPX1/SERPINB9/DYNLT1 33 GO:0001890 placenta development 22/742 144/18722 5.50418480294548e-08 1.51059294036393e-05 SPINT1/KRT19/RPS6/SPINT2/BSG/BPTF/GJA1/CTSV/ZFP36L1/KRT8/BMP7/NR2F2/MME/ASH1L/JUNB/ST14/HECTD1/ADM/CITED2/EPAS1/HES1/IGF2 22 GO:0032970 regulation of actin filament-based process 40/742 396/18722 6.13108713419599e-08 1.59408265489096e-05 AKAP9/LRP1/RHOB/IQGAP2/MET/KANK1/CAV1/IQGAP1/DSP/DSG2/DSC2/SPTAN1/NRP1/TACSTD2/JAM3/GJA5/PFN1/TMSB4X/SPTBN1/SLC9A1/ACTG1/DLG1/AKAP13/WASF2/RASA1/ROCK1/TRIOBP/PPP1R9A/ATP1A1/KANK4/ID1/RHOBTB3/S100A10/CDC42/ARPC3/DSTN/RHOA/PHPT1/CAPZB/COTL1 40 GO:0022604 regulation of cell morphogenesis 34/742 309/18722 7.88361437361584e-08 1.94725275028311e-05 FBLN1/DAG1/CLDN4/P4HB/RHOB/ALDOA/MACF1/KANK1/MYH10/PRKDC/NRP1/TACSTD2/CALR/CUX1/ANXA1/PHIP/DLG1/DIAPH1/ACTN4/RASA1/TRIOBP/BRWD1/CFL1/DHX36/FMNL2/OBSL1/HEXB/MYL12B/RHOBTB3/S100A10/CDC42/MYL12A/RHOA/CAPZB 34 GO:0001892 embryonic placenta development 16/742 82/18722 1.14311911562948e-07 2.58625754307382e-05 SPINT1/KRT19/SPINT2/BPTF/ZFP36L1/KRT8/BMP7/NR2F2/JUNB/ST14/HECTD1/ADM/CITED2/EPAS1/HES1/IGF2 16 GO:0034976 response to endoplasmic reticulum stress 30/742 256/18722 1.15177461432438e-07 2.58625754307382e-05 JUN/HSP90B1/HSPA5/P4HB/PDIA3/UFL1/ERP29/CAV1/PDIA4/PPP1R15A/CCDC47/CALR/TMEM259/HSPA1A/UBXN4/OS9/CANX/EIF4G1/PMAIP1/DNAJB14/FAF2/CREB3L2/ATF6/MBTPS1/SERINC3/DDIT3/EIF2AK4/HM13/BCAP31/UFC1 30 GO:0072001 renal system development 33/742 302/18722 1.44088405290103e-07 3.09476835710046e-05 LRP2/FBN1/ADAMTS6/LAMA5/LGR5/SERPINF1/ENPEP/IQGAP1/LGR4/SOX4/ADAMTS1/PBX1/EGR1/DLG5/FRAS1/NRP1/BMP7/TACSTD2/MME/GLI3/NF1/MAGED1/DLG1/C1GALT1/NIPBL/IRX2/SEC61A1/IFT27/ARID5B/GATA3/HES1/RHOA/HPGD 33 GO:0051222 positive regulation of protein transport 33/742 303/18722 1.55736936818414e-07 3.20558528284569e-05 EGFR/LRP1/TCAF1/CDH1/KCNN4/WLS/MYH10/SOX4/GJA1/DYNLL1/ANK3/TPR/ISL1/FRMD4A/CD81/GLI3/KIF5B/B3GAT3/STOM/NMT1/TCF7L2/VAMP2/PPIA/PCM1/HUWE1/CLN3/RAN/BCAP31/LEPROT/CDC42/PHPT1/UBE2L3/YWHAE 33 GO:1904951 positive regulation of establishment of protein localization 34/742 319/18722 1.69998300974506e-07 3.35916642725623e-05 EGFR/LRP1/TCAF1/CDH1/KCNN4/WLS/MYH10/SOX4/GJA1/DYNLL1/ANK3/TPR/ISL1/FRMD4A/CD81/GLI3/KIF5B/B3GAT3/STOM/NMT1/TCF7L2/VAMP2/PPIA/PCM1/HUWE1/CLN3/RAN/BCAP31/LEPROT/CDC42/PHPT1/UBE2L3/YWHAE/CCT3 34 GO:0001822 kidney development 32/742 293/18722 2.25089090593396e-07 4.14526708513079e-05 LRP2/FBN1/ADAMTS6/LAMA5/SERPINF1/ENPEP/IQGAP1/LGR4/SOX4/ADAMTS1/PBX1/EGR1/DLG5/FRAS1/NRP1/BMP7/TACSTD2/MME/GLI3/NF1/MAGED1/DLG1/C1GALT1/NIPBL/IRX2/SEC61A1/IFT27/ARID5B/GATA3/HES1/RHOA/HPGD 32 GO:0001655 urogenital system development 35/742 338/18722 2.26563180766258e-07 4.14526708513079e-05 LRP2/FBN1/ADAMTS6/LAMA5/PSAP/LGR5/SERPINF1/ENPEP/IQGAP1/LGR4/SOX4/ADAMTS1/PBX1/EGR1/DLG5/FRAS1/NRP1/BMP7/TACSTD2/MME/ANXA1/GLI3/NF1/MAGED1/DLG1/C1GALT1/NIPBL/IRX2/SEC61A1/IFT27/ARID5B/GATA3/HES1/RHOA/HPGD 35 GO:0060562 epithelial tube morphogenesis 34/742 325/18722 2.64754164869691e-07 4.67101990877241e-05 LRP2/SPINT1/LAMA5/DAG1/RHOB/MET/SPINT2/LGR5/LGR4/SOX4/PBX1/DLG5/LRP5/NRP1/BMP7/TACSTD2/LMO4/FOLR1/PFN1/GLI3/MAGED1/DLG1/BRD2/ST14/IRX2/HECTD1/ADM/FOXP1/KDM5B/CITED2/GATA3/HES1/RHOA/CSNK2B 34 GO:0033157 regulation of intracellular protein transport 27/742 229/18722 4.35908466875004e-07 7.23921001841272e-05 TCAF1/CDH1/LMAN1/ANK3/GCC2/TPR/FERMT1/CD81/GLI3/KIF5B/OS9/B3GAT3/STOM/NUCB1/NMT1/TCF7L2/VAMP2/PTPN14/PCM1/TXN/HUWE1/RAN/BCAP31/LEPROT/CDC42/UBE2L3/YWHAE 27 GO:0031589 cell-substrate adhesion 36/742 363/18722 4.39628138770003e-07 7.23921001841272e-05 FBLN1/ITGB4/LRP1/LAMA5/ITGAV/LAMB1/ITGB1/DAG1/ITGA6/P4HB/BCAM/CCDC80/LAMC1/MACF1/KANK1/UTRN/IQGAP1/NRP1/TACSTD2/JAM3/FERMT1/CALR/SLC9A1/CDK6/ITGB5/ACTG1/NF1/PTPRA/ACTN4/RASA1/ROCK1/TRIOBP/ID1/S100A10/CDC42/RHOA 36 GO:0061008 hepaticobiliary system development 21/742 150/18722 4.97279937531012e-07 7.92439642388129e-05 EGFR/RPS16/MET/RPL19/TGFBR3/LSR/SRSF5/ANXA1/GLI3/NF1/UPF2/MAN2A1/NIPBL/SEC63/RB1CC1/ARID5B/PRKCSH/CITED2/KRT18/HES1/CSNK2B 21 GO:0008380 RNA splicing 40/742 434/18722 6.89873191540077e-07 0.000106499173943999 AHNAK/SON/RPS13/SF1/ZC3H13/FUS/RBM39/RPS26/SLC38A2/SRRM2/PRPF38B/SCAF11/NPM1/PNN/RBM25/SRSF5/HSPA1A/PPIG/LUC7L3/TRA2B/YBX1/HNRNPA1/DDX17/PDCD7/SRSF7/DDX46/THOC2/POLR2A/SRSF11/SRSF6/CELF1/ZNF638/CIRBP/SF3B1/PRDX6/DDX5/SNRPD2/HNRNPC/MBNL3/SNRPC 40 GO:0010810 regulation of cell-substrate adhesion 26/742 221/18722 7.41277373485926e-07 0.000110966976515772 FBLN1/LRP1/DAG1/ITGA6/P4HB/CCDC80/MACF1/KANK1/UTRN/IQGAP1/NRP1/TACSTD2/FERMT1/CALR/SLC9A1/CDK6/ACTG1/NF1/PTPRA/ACTN4/RASA1/ROCK1/TRIOBP/S100A10/CDC42/RHOA 26 GO:0006413 translational initiation 18/742 118/18722 9.02974281453532e-07 0.000131196851481778 RPL13A/RPS3A/EIF3A/PPP1R15A/NPM1/TPR/EIF4G1/RPS17/EIF3H/EIF2AK4/LARP1/HSPB1/EIF1/EIF2S2/EIF3F/EIF4H/EIF3I/EIF4B 18 GO:0007044 cell-substrate junction assembly 16/742 95/18722 9.35162830098608e-07 0.000131991553733918 ITGB4/LRP1/ITGA6/LAMC1/MACF1/PLEC/IQGAP1/DST/NRP1/SLC9A1/ACTG1/PTPRA/ROCK1/S100A10/TLN1/RHOA 16 GO:0031099 regeneration 24/742 198/18722 1.14823337066047e-06 0.000157563134751742 EGFR/LRP1/GRN/DAG1/RPS16/RPL19/TGFBR3/PTPRF/JAM3/ISL1/SRSF5/FOLR1/CD81/ANXA1/GLI3/UPF2/PTPN12/MTR/ADM/CPQ/GPX1/NREP/ANXA3/CSNK2B 24 GO:0071826 ribonucleoprotein complex subunit organization 26/742 227/18722 1.2394019570375e-06 0.000165476909939601 RPLP0/RPL13A/RPL23A/RPL6/SF1/EIF3A/RPL24/PRKDC/SCAF11/SRSF5/RPL3/KIF5B/LUC7L3/EIF3H/SRSF6/CELF1/SF3B1/SNRPD2/ADAR/PTGES3/EIF2S2/EIF3F/EIF4H/SNRPC/EIF3I/EIF4B 26 GO:0043434 response to peptide hormone 38/742 414/18722 1.44725135588816e-06 0.000182731709417972 ATP2B1/FBN1/SLC2A1/DAG1/JUND/BSG/KANK1/CAV1/IQGAP1/TGFBR3/GJA1/EGR1/PRKDC/ZFP36L1/CSH1/LRP5/IGF1R/BMP7/POR/SRSF5/ESRRA/VPS13C/ANXA1/SLC9A1/PHIP/BTG1/PTPRA/ROCK1/VAMP2/ADM/SRSF6/HADHA/PKM/PARP1/LEPROT/CYP11A1/IGF2/CACYBP 38 GO:0001889 liver development 20/742 147/18722 1.46565896156243e-06 0.000182731709417972 EGFR/RPS16/MET/RPL19/TGFBR3/LSR/SRSF5/ANXA1/GLI3/NF1/UPF2/MAN2A1/SEC63/RB1CC1/ARID5B/PRKCSH/CITED2/KRT18/HES1/CSNK2B 20 GO:0034975 protein folding in endoplasmic reticulum 6/742 11/18722 1.47960898314148e-06 0.000182731709417972 HSP90B1/HSPA5/P4HB/PDIA3/CALR/CANX 6 GO:0048545 response to steroid hormone 33/742 339/18722 1.99722027729535e-06 0.000237388570247246 EGFR/ATP2B1/FOS/CLDN4/SERPINF1/FOSB/UFL1/DUSP1/CAV1/CTSV/ZFP36L1/AGL/BMP7/ISL1/CALR/ESRRA/ANXA1/ARID1A/GLB1/ATP1A1/DDX17/NCOR1/PDCD7/ADM/FOXP1/CALM1/DDX5/PARP1/PTGES3/RHOA/ANXA3/UBE2L3/LBH 33 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 34/742 355/18722 2.01828339076606e-06 0.000237388570247246 JUN/LRP2/FBN2/FBN1/FOS/PEG10/HSPA5/LRP1/GLG1/CRIM1/CAV1/TGFBR3/EGR1/LTBP1/BMP7/FERMT1/FOLR1/SPTBN1/HSPA1A/ITGB5/FSTL1/LTBP3/USP9X/FUT8/CITED2/DDX5/ID1/PARP1/HES1/NREP/HPGD/CSNK2B/PDCD4/SDCBP 34 GO:0050821 protein stabilization 23/742 191/18722 2.14180026129373e-06 0.0002438410063203 GAPDH/GRN/AAK1/SOX4/RPL23/PLPP3/RTN4/NPM1/CALR/PFN1/HSPA1A/TRIM44/P3H1/CTNND1/HSPA1B/GNAQ/LAMP2/USP9X/USP27X/LAMP1/TBL1X/PTGES3/CCT3 23 GO:0150115 cell-substrate junction organization 16/742 101/18722 2.17186321418891e-06 0.0002438410063203 ITGB4/LRP1/ITGA6/LAMC1/MACF1/PLEC/IQGAP1/DST/NRP1/SLC9A1/ACTG1/PTPRA/ROCK1/S100A10/TLN1/RHOA 16 GO:0043542 endothelial cell migration 29/742 279/18722 2.26808413067067e-06 0.000245460581058443 NRP2/GRN/ITGB1/RHOB/MET/SERPINF1/EPHB4/PLPP3/S100P/DPP4/NRP1/ATP2B4/NR2F2/CALR/MIA3/TMSB4X/ANXA1/FSTL1/LGMN/NF1/EMC10/FOXP1/GATA3/HSPB1/GPX1/ID1/RHOA/ANXA3/CSNK2B 29 GO:0022618 ribonucleoprotein complex assembly 25/742 220/18722 2.285665329694e-06 0.000245460581058443 RPLP0/RPL13A/RPL23A/RPL6/SF1/EIF3A/RPL24/PRKDC/SCAF11/SRSF5/RPL3/LUC7L3/EIF3H/SRSF6/CELF1/SF3B1/SNRPD2/ADAR/PTGES3/EIF2S2/EIF3F/EIF4H/SNRPC/EIF3I/EIF4B 25 GO:0071559 response to transforming growth factor beta 27/742 256/18722 3.82858419693227e-06 0.000402408636869051 JUN/FBN2/FBN1/FOS/PEG10/HSPA5/GLG1/COL4A2/CAV1/TGFBR3/ZFP36L1/LTBP1/ZFHX3/FERMT1/FOLR1/HSPA1A/ITGB5/LTBP3/ROCK1/USP9X/FUT8/CITED2/ID1/PARP1/NREP/HPGD/SDCBP 27 GO:0007179 transforming growth factor beta receptor signaling pathway 23/742 198/18722 3.97166288011907e-06 0.000408750304745587 JUN/FBN2/FBN1/FOS/PEG10/HSPA5/GLG1/CAV1/TGFBR3/LTBP1/FERMT1/FOLR1/HSPA1A/ITGB5/LTBP3/USP9X/FUT8/CITED2/ID1/PARP1/NREP/HPGD/SDCBP 23 GO:0001649 osteoblast differentiation 25/742 229/18722 4.71402197546158e-06 0.000475250378750617 FBN2/RRBP1/JUND/CRIM1/UFL1/LGR4/IL6ST/ATP6AP1/LRP5/BMP7/CCDC47/SUCO/ESRRA/CDK6/GLI3/NF1/JUNB/SMOC1/DDX5/ADAR/CLTC/HNRNPC/ATRAID/TPM4/IGF2 25 GO:0002183 cytoplasmic translational initiation 9/742 34/18722 4.94127984011695e-06 0.000488198448203554 RPL13A/EIF3A/EIF4G1/EIF3H/EIF2S2/EIF3F/EIF4H/EIF3I/EIF4B 9 GO:0045785 positive regulation of cell adhesion 38/742 437/18722 5.23146070666783e-06 0.000496988767133444 CD46/ADGRG1/ITGAV/DAG1/ITGA6/P4HB/CCDC80/TFRC/UTRN/CAV1/IQGAP1/SOX4/IL6ST/PLPP3/DPP4/ZFHX3/ANK3/NRP1/BMP7/FERMT1/CALR/NFAT5/CD81/ANXA1/CDK6/GLI3/ROCK1/TRIOBP/CD55/CITED2/GATA3/DOCK8/S100A10/HES1/CDC42/TGM2/RHOA/IGF2 38 GO:0050673 epithelial cell proliferation 38/742 437/18722 5.23146070666783e-06 0.000496988767133444 EGFR/NRP2/GRN/LAMB1/LAMC1/LGR5/SERPINF1/CAV1/LGR4/TGFBR3/GJA1/PRKDC/ZFP36L1/FLT1/RTN4/NRP1/ISL1/FERMT1/NR2F2/CDK6/NF1/NCSTN/MYDGF/MAGED1/DLG1/EMC10/TCF7L2/PURA/SRSF6/KDM5B/GATA3/MARVELD3/GPX1/ID1/HES1/CDC42/SERPINB1/IGF2 38 GO:1903829 positive regulation of cellular protein localization 28/742 276/18722 5.39711252987713e-06 0.000503051620709303 EGFR/LRP1/TCAF1/CDH1/ITGB1/TFRC/IQGAP1/ANK3/RTN4/NPM1/TPR/ATP2B4/SPTBN1/CD81/GLI3/KIF5B/DLG1/STOM/SLC5A3/NMT1/HUWE1/PARP1/CLN3/RAN/LEPROT/RAB11A/UBE2L3/CCT3 28 GO:0090316 positive regulation of intracellular protein transport 20/742 160/18722 5.52326142224596e-06 0.000505276137516575 TCAF1/CDH1/ANK3/TPR/CD81/GLI3/KIF5B/B3GAT3/STOM/NMT1/TCF7L2/VAMP2/PCM1/HUWE1/RAN/BCAP31/LEPROT/CDC42/UBE2L3/YWHAE 20 GO:0032956 regulation of actin cytoskeleton organization 33/742 357/18722 6.09302209160967e-06 0.000542220983289878 LRP1/RHOB/IQGAP2/MET/KANK1/IQGAP1/SPTAN1/NRP1/TACSTD2/JAM3/PFN1/TMSB4X/SPTBN1/SLC9A1/ACTG1/DLG1/AKAP13/WASF2/RASA1/ROCK1/TRIOBP/PPP1R9A/KANK4/ID1/RHOBTB3/S100A10/CDC42/ARPC3/DSTN/RHOA/PHPT1/CAPZB/COTL1 33 GO:0007346 regulation of mitotic cell cycle 39/742 457/18722 6.14663462838728e-06 0.000542220983289878 EGFR/APP/DUSP1/IQGAP1/SOX4/RPL26/ADAMTS1/PBX1/PRKDC/ZFP36L1/PKN2/LRP5/PPP1R10/BMP7/TPR/BRD4/ANXA1/DDB1/PHIP/LGMN/EIF4G1/BTG1/DLG1/CTDSPL/BRD7/USP22/OBSL1/HES1/CDC42/NEK6/IGF2/RAB11A/ANAPC11/CKS1B/YWHAE/UBE2C/PSME2/LCMT1/SDCBP 39 GO:0051235 maintenance of location 31/742 326/18722 6.55778947691672e-06 0.000567012238788549 FBN2/AKAP9/HSP90B1/FBN1/HSPA5/ITGAV/FTH1/GAA/CAV1/GJA1/LTBP1/ANK3/GSTO1/CALR/TMSB4X/VPS13C/ARHGAP21/OS9/S100A9/GPAA1/PLIN2/DIAPH1/CDS1/DDIT3/TXN/NFKBIA/CALM1/MEST/SKP1/HEXB/CALM2 31 GO:0098901 regulation of cardiac muscle cell action potential 8/742 27/18722 6.65722871452142e-06 0.000567012238788549 AKAP9/CAV1/DSP/DSG2/DSC2/GJA5/DLG1/CALM1 8 GO:0061337 cardiac conduction 15/742 98/18722 6.94728096809406e-06 0.000581687592921774 AKAP9/ATP2B1/CAV1/GJA1/DSP/DSG2/DSC2/ATP2B4/ISL1/GJA5/SLC9A1/ATP1A1/CALM1/CALM2/YWHAE 15 GO:0060348 bone development 23/742 205/18722 7.13117405659219e-06 0.000587133330659424 FBN1/GLG1/RPL13/GJA1/TRIP11/BBX/SERPINH1/ATP6AP1/LRP5/POR/SLC38A10/GLI3/P3H1/LTBP3/AKAP13/WASF2/FOXP1/TMEM107/CITED2/NOTUM/TGM2/RHOA/HSD17B1 23 GO:0045787 positive regulation of cell cycle 30/742 313/18722 7.8806502454378e-06 0.000638203478892832 EGFR/APP/DYNC1H1/ATRX/ADAMTS1/PBX1/SLC6A4/PKN2/LRP5/PPP1R10/NPM1/TPR/BRD4/CALR/ANXA1/PHIP/LGMN/CCPG1/EIF4G1/CITED2/USP22/HES1/CDC42/RHOA/IGF2/RAB11A/ANAPC11/CKS1B/UBE2C/RANBP1 30 GO:2001242 regulation of intrinsic apoptotic signaling pathway 20/742 164/18722 8.0512980209565e-06 0.000641506648766534 TPT1/P4HB/ERP29/CAV1/MIF/RPL26/HSPA1A/ENO1/S100A9/PMAIP1/SERINC3/PPIA/DDIT3/HSPB1/GPX1/PARP1/BCAP31/SIAH1/VDAC2/EIF5A 20 GO:0031647 regulation of protein stability 29/742 298/18722 8.30642293273496e-06 0.000651329036312869 GAPDH/GRN/AAK1/SOX4/RPL23/PRKDC/PLPP3/DDOST/RTN4/NPM1/CTSA/CALR/PFN1/HSPA1A/CD81/TRIM44/P3H1/CTNND1/HSPA1B/GNAQ/CMTM6/LAMP2/USP9X/USP27X/LAMP1/TBL1X/SIAH1/PTGES3/CCT3 29 GO:0048024 regulation of mRNA splicing, via spliceosome 15/742 101/18722 1.01332588797917e-05 0.00078216091978392 SON/SF1/RBM39/NPM1/RBM25/TRA2B/HNRNPA1/DDX17/SRSF7/SRSF6/CELF1/CIRBP/PRDX6/DDX5/MBNL3 15 GO:0001701 in utero embryonic development 33/742 367/18722 1.08747397360887e-05 0.000826480219942738 SPINT1/KRT19/ITGB1/SPINT2/N4BP2L2/RPL13/BPTF/ZFP36L1/KRT8/RTN4/BMP7/NR2F2/GLI3/KIDINS220/JUNB/BTF3/MAN2A1/RBBP6/YBX1/ST14/NMT1/HECTD1/SLC39A1/FUT8/ADM/RTF1/CITED2/GATA3/EPAS1/HM13/HES1/EIF2S2/IGF2 33 GO:0031032 actomyosin structure organization 22/742 196/18722 1.11398192351654e-05 0.000833798591238134 KRT19/ITGB1/MET/PLEC/MYH10/KRT8/NRP1/TACSTD2/PFN1/SLC9A1/ITGB5/ACTG1/AKAP13/FRMD6/WASF2/ROCK1/PPP1R9A/OBSL1/S100A10/CDC42/RHOA/CNN3 22 GO:0003279 cardiac septum development 15/742 103/18722 1.29215415361905e-05 0.00095272261475793 LRP2/NRP2/ADAMTS6/TGFBR3/SOX4/TRIP11/NRP1/BMP7/LMO4/ISL1/GJA5/HECTD1/CITED2/GATA3/HES1 15 GO:2001233 regulation of apoptotic signaling pathway 32/742 356/18722 1.48399994149468e-05 0.00107808231043878 TPT1/ITGAV/ITGA6/P4HB/CTSC/PDIA3/ERP29/CAV1/MIF/RPL26/NRP1/HSPA1A/ENO1/PHIP/S100A9/PMAIP1/MAGED1/HSPA1B/TIMP3/TCF7L2/SERINC3/PPIA/DDIT3/RB1CC1/HSPB1/GPX1/PARP1/SIAH2/BCAP31/SIAH1/VDAC2/EIF5A 32 GO:0007015 actin filament organization 37/742 441/18722 1.54633607463395e-05 0.00110708698676692 HSP90B1/RHOB/ALDOA/IQGAP2/MET/PLEC/KANK1/SPTAN1/NRP1/TACSTD2/PFN1/TMSB4X/SPTBN1/SLC9A1/ITGB5/ACTG1/FAT1/DLG1/DIAPH1/WASF2/RASA1/ROCK1/TRIOBP/PPP1R9A/KANK4/CFL1/MSRB2/ID1/RHOBTB3/S100A10/TPM4/CDC42/ARPC3/DSTN/RHOA/CAPZB/COTL1 37 GO:0001503 ossification 35/742 408/18722 1.6374636111296e-05 0.00115558146271146 FBN2/EGFR/ATP2B1/RRBP1/SLC26A2/JUND/CRIM1/UFL1/LGR4/IL6ST/PBX1/ATP6AP1/LRP5/BMP7/CCDC47/SUCO/ESRRA/CDK6/GLI3/NF1/JUNB/LTBP3/NIPBL/SMOC1/DHX36/ATP6V1B1/DDX5/ADAR/CLTC/NOTUM/HNRNPC/ATRAID/TPM4/RHOA/IGF2 35 GO:0045185 maintenance of protein location 14/742 93/18722 1.69895002065503e-05 0.00118208635239941 FBN2/FBN1/HSPA5/CAV1/GJA1/LTBP1/ANK3/TMSB4X/VPS13C/OS9/GPAA1/TXN/NFKBIA/SKP1 14 GO:0016055 Wnt signaling pathway 37/742 444/18722 1.79472792719173e-05 0.00121571263407243 EGFR/LRP1/APP/LGR5/MACF1/KANK1/WLS/CAV1/RNF43/LGR4/SOX4/EGR1/TLE4/PLPP3/LRP5/ISL1/FERMT1/FOLR1/GLI3/DDB1/ZNRF3/ATP6AP2/CTNND1/TPBG/TCF7L2/GNAQ/DDIT3/BRD7/RTF1/GATA3/TBL1X/SIAH2/NOTUM/CDC42/RHOA/CSNK2B/CCNE1 37 GO:0032388 positive regulation of intracellular transport 22/742 202/18722 1.79649842686817e-05 0.00121571263407243 TCAF1/CDH1/DYNC1H1/ANK3/TPR/CD81/GLI3/KIF5B/B3GAT3/STOM/PGAP1/NMT1/TCF7L2/VAMP2/PCM1/HUWE1/RAN/BCAP31/LEPROT/CDC42/UBE2L3/YWHAE 22 GO:1905477 positive regulation of protein localization to membrane 15/742 106/18722 1.83816304304758e-05 0.00122709803143987 EGFR/LRP1/TCAF1/ITGB1/ANK3/ATP2B4/SPTBN1/CD81/KIF5B/DLG1/STOM/SLC5A3/NMT1/CLN3/RAB11A 15 GO:0198738 cell-cell signaling by wnt 37/742 446/18722 1.98009367102894e-05 0.0013042216979844 EGFR/LRP1/APP/LGR5/MACF1/KANK1/WLS/CAV1/RNF43/LGR4/SOX4/EGR1/TLE4/PLPP3/LRP5/ISL1/FERMT1/FOLR1/GLI3/DDB1/ZNRF3/ATP6AP2/CTNND1/TPBG/TCF7L2/GNAQ/DDIT3/BRD7/RTF1/GATA3/TBL1X/SIAH2/NOTUM/CDC42/RHOA/CSNK2B/CCNE1 37 GO:0007229 integrin-mediated signaling pathway 15/742 107/18722 2.06090143900181e-05 0.00133958593535118 ITGB4/LAMA5/ITGAV/ITGB1/ITGA6/ADAMTS1/PLPP3/DST/NRP1/FERMT1/ITGB5/PTPRA/FUT8/TLN1/CDC42 15 GO:1905475 regulation of protein localization to membrane 20/742 175/18722 2.12228398526631e-05 0.00135808054407773 EGFR/LRP1/TCAF1/ITGB1/DAG1/ANK3/ATP2B4/TMEM59/SPTBN1/CD81/KIF5B/GPC1/DLG1/STOM/SLC5A3/NMT1/HECTD1/CLTC/CLN3/RAB11A 20 GO:0010649 regulation of cell communication by electrical coupling 6/742 16/18722 2.16243165673344e-05 0.00135808054407773 CAV1/GJA1/ANK3/GJA5/CALM1/CALM2 6 GO:0071560 cellular response to transforming growth factor beta stimulus 25/742 250/18722 2.17182921016479e-05 0.00135808054407773 JUN/FBN2/FBN1/FOS/PEG10/HSPA5/GLG1/COL4A2/CAV1/TGFBR3/ZFP36L1/LTBP1/FERMT1/FOLR1/HSPA1A/ITGB5/LTBP3/USP9X/FUT8/CITED2/ID1/PARP1/NREP/HPGD/SDCBP 25 GO:0044706 multi-multicellular organism process 23/742 220/18722 2.2657896989432e-05 0.0013946809793728 FOS/FBLN1/ITGB4/SLC2A1/CLDN4/FOSB/BSG/SLC38A1/SLC38A2/GJA1/MAGED2/CTSV/SLC19A1/SLC6A4/PRLR/NR2F2/CALR/ASH1L/JUNB/ADM/CITED2/HEXB/HPGD 23 GO:0034446 substrate adhesion-dependent cell spreading 15/742 108/18722 2.30716188549727e-05 0.0013946809793728 FBLN1/LAMA5/ITGAV/LAMB1/P4HB/LAMC1/KANK1/NRP1/TACSTD2/CALR/ACTN4/TRIOBP/S100A10/CDC42/RHOA 15 GO:0003015 heart process 25/742 251/18722 2.32373977583235e-05 0.0013946809793728 AKAP9/ATP2B1/GAA/CAV1/GJA1/DSP/DSG2/DSC2/GSTO1/ATP2B4/ISL1/GJA5/SLC9A1/ADRB1/DLG1/AKAP13/ATP1A1/ADM/CALM1/EPAS1/GPX1/CDC42/CYP2J2/CALM2/YWHAE 25 GO:0051384 response to glucocorticoid 18/742 148/18722 2.34328990461422e-05 0.0013946809793728 EGFR/ATP2B1/FOS/SERPINF1/FOSB/DUSP1/CTSV/ZFP36L1/AGL/ISL1/ANXA1/GLB1/PDCD7/ADM/CALM1/RHOA/ANXA3/UBE2L3 18 GO:0008016 regulation of heart contraction 22/742 206/18722 2.4409206601265e-05 0.00141724942073106 AKAP9/ATP2B1/GAA/CAV1/GJA1/DSP/DSG2/DSC2/GSTO1/ATP2B4/ISL1/GJA5/SLC9A1/ADRB1/DLG1/ATP1A1/ADM/CALM1/EPAS1/CYP2J2/CALM2/YWHAE 22 GO:0010769 regulation of cell morphogenesis involved in differentiation 14/742 96/18722 2.45646341899616e-05 0.00141724942073106 FBLN1/P4HB/KANK1/PRKDC/NRP1/TACSTD2/CALR/CUX1/ACTN4/TRIOBP/DHX36/OBSL1/S100A10/CDC42 14 GO:1902903 regulation of supramolecular fiber organization 33/742 382/18722 2.46727631949133e-05 0.00141724942073106 AKAP9/APP/IQGAP2/MET/CLIP1/KANK1/SPTAN1/NRP1/TACSTD2/PFN1/TMSB4X/SPTBN1/HSPA1A/SLC9A1/ACTG1/DLG1/AKAP13/WASF2/RASA1/HSPA1B/ROCK1/TRIOBP/PPP1R9A/KANK4/GPX1/ID1/S100A10/CDC42/ARPC3/DSTN/RHOA/CAPZB/COTL1 33 GO:0030198 extracellular matrix organization 28/742 301/18722 2.71077375763653e-05 0.0015392209612327 COL14A1/ADAMTSL4/SPINT1/FBLN1/LRP1/ADAMTS6/APP/LAMB1/ITGB1/DAG1/VWA1/CCDC80/LAMC1/SPINT2/COL4A2/CAV1/ADAMTS1/CTSV/DPP4/SERPINH1/MMP15/FERMT1/NF1/LTBP3/CST3/SMOC1/ADAMTS19/PRDX4 28 GO:0007565 female pregnancy 21/742 193/18722 2.80762056744352e-05 0.00157609609126943 FOS/FBLN1/ITGB4/SLC2A1/CLDN4/FOSB/BSG/SLC38A1/SLC38A2/GJA1/MAGED2/CTSV/SLC19A1/PRLR/NR2F2/CALR/ASH1L/JUNB/ADM/CITED2/HPGD 21 GO:0043062 extracellular structure organization 28/742 302/18722 2.87812264480914e-05 0.00159751976015249 COL14A1/ADAMTSL4/SPINT1/FBLN1/LRP1/ADAMTS6/APP/LAMB1/ITGB1/DAG1/VWA1/CCDC80/LAMC1/SPINT2/COL4A2/CAV1/ADAMTS1/CTSV/DPP4/SERPINH1/MMP15/FERMT1/NF1/LTBP3/CST3/SMOC1/ADAMTS19/PRDX4 28 GO:0034329 cell junction assembly 35/742 420/18722 3.00849696892361e-05 0.00164033676314584 ITGB4/LRP1/CDH1/APP/ITGA6/CLDN4/LAMC1/MACF1/PLEC/CAV1/IQGAP1/GJA1/PKN2/LSR/DLG5/DST/NRP1/JAM3/GJA5/SLC9A1/ACTG1/EIF4G1/CTNND1/DLG1/PTPRA/ROCK1/PPP1R9A/TPBG/OBSL1/MARVELD3/S100A10/TLN1/CDC42/RHOA/SDCBP 35 GO:0050684 regulation of mRNA processing 17/742 137/18722 3.02167298474233e-05 0.00164033676314584 SON/SF1/RBM39/ZFP36L1/NPM1/RBM25/TRA2B/HNRNPA1/DDX17/SRSF7/DHX36/SRSF6/CELF1/CIRBP/PRDX6/DDX5/MBNL3 17 GO:0070972 protein localization to endoplasmic reticulum 12/742 74/18722 3.15506690542433e-05 0.00169413375139089 HSPA5/SEC62/GJA1/RTN4/PPP1R15A/MIA3/OS9/GPAA1/SEC61A1/SEC63/SPCS2/BCAP31 12 GO:0045229 external encapsulating structure organization 28/742 304/18722 3.24119795048173e-05 0.00170094281981709 COL14A1/ADAMTSL4/SPINT1/FBLN1/LRP1/ADAMTS6/APP/LAMB1/ITGB1/DAG1/VWA1/CCDC80/LAMC1/SPINT2/COL4A2/CAV1/ADAMTS1/CTSV/DPP4/SERPINH1/MMP15/FERMT1/NF1/LTBP3/CST3/SMOC1/ADAMTS19/PRDX4 28 GO:0032386 regulation of intracellular transport 30/742 337/18722 3.26956417190138e-05 0.00170094281981709 TCAF1/CDH1/LMAN1/DYNC1H1/ANK3/GCC2/TPR/FERMT1/CD81/GLI3/KIF5B/OS9/B3GAT3/STOM/PGAP1/NUCB1/NMT1/TCF7L2/VAMP2/PTPN14/LAMP1/PCM1/TXN/HUWE1/RAN/BCAP31/LEPROT/CDC42/UBE2L3/YWHAE 30 GO:0007623 circadian rhythm 22/742 210/18722 3.28616884757799e-05 0.00170094281981709 JUN/EGFR/JUND/CLDN4/MYCBP2/LGR4/EGR1/PRKDC/SLC6A4/ZFHX3/NAGLU/DDB1/MAGED1/ADRB1/KDM5A/NCOR1/GNAQ/USP9X/HUWE1/NR2F6/ID1/SIAH2 22 GO:0042060 wound healing 35/742 422/18722 3.31932763315619e-05 0.00170094281981709 F5/EGFR/FBLN1/ITGB1/DAG1/LMAN1/CLDN4/MACF1/PLEC/KANK1/CAV1/IL6ST/GJA1/DSP/PLPP3/ANXA5/DST/FERMT1/MIA3/ANXA1/GLI3/ACTG1/NF1/SYT7/GNAQ/PPIA/ERBB3/SRSF6/GNA12/HSPB1/GPX1/TFPI2/TLN1/MYL12A/RHOA 35 GO:0021915 neural tube development 18/742 152/18722 3.36491678663862e-05 0.00170094281981709 LRP2/SPINT1/SPINT2/SOX4/ZFP36L1/BMP7/LMO4/FOLR1/PFN1/GLI3/ATP6AP2/BRD2/ST14/HECTD1/ADM/TMEM107/CITED2/HES1 18 GO:0060047 heart contraction 24/742 241/18722 3.37434000692458e-05 0.00170094281981709 AKAP9/ATP2B1/GAA/CAV1/GJA1/DSP/DSG2/DSC2/GSTO1/ATP2B4/ISL1/GJA5/SLC9A1/ADRB1/DLG1/ATP1A1/ADM/CALM1/EPAS1/GPX1/CDC42/CYP2J2/CALM2/YWHAE 24 GO:0001763 morphogenesis of a branching structure 21/742 196/18722 3.53539099509451e-05 0.00176412439553201 SPINT1/LAMA5/DAG1/MET/SPINT2/LGR4/PBX1/DLG5/RTN4/LRP5/NRP1/BMP7/TACSTD2/GLI3/MAGED1/DLG1/RERE/ST14/ADM/KDM5B/TGM2 21 GO:0031960 response to corticosteroid 19/742 167/18722 3.60695955616298e-05 0.00178183802074451 EGFR/ATP2B1/FOS/SERPINF1/FOSB/DUSP1/CTSV/ZFP36L1/AGL/ISL1/ANXA1/GLB1/PDCD7/ADM/CALM1/PARP1/RHOA/ANXA3/UBE2L3 19 GO:0007568 aging 30/742 339/18722 3.65241191365504e-05 0.00178642721321346 JUN/ATP2B1/FOS/LRP1/APP/DAG1/JUND/RPN2/CTSC/SERPINF1/COL4A2/MIF/CTSV/PRKDC/NPM1/CALR/MME/CDK6/CANX/YBX1/PPP1R9A/ADM/SEC63/YPEL3/CITED2/NEK6/GPX4/PDCD4/HMGA1/CACYBP 30 GO:0016052 carbohydrate catabolic process 18/742 154/18722 4.01099728156952e-05 0.00194219600300617 GAPDH/APP/LDHA/GAA/ALDOA/AGL/LRP5/MANBA/TPI1/ENO1/GUSB/GLB1/NCOR1/FUT8/RB1CC1/PKM/HEXB/PYGL 18 GO:0051651 maintenance of location in cell 22/742 213/18722 4.0833822714202e-05 0.00194219600300617 AKAP9/HSP90B1/HSPA5/FTH1/GAA/CAV1/GJA1/ANK3/GSTO1/CALR/TMSB4X/VPS13C/ARHGAP21/OS9/S100A9/GPAA1/DIAPH1/DDIT3/TXN/CALM1/SKP1/CALM2 22 GO:0010232 vascular transport 13/742 88/18722 4.14138565300328e-05 0.00194219600300617 LRP2/LRP1/SLC2A1/TFRC/SLC38A1/SLC38A2/GJA1/SLC1A5/SLC19A1/ATP2B4/SLC16A12/SLC5A3/SLC16A1 13 GO:0086001 cardiac muscle cell action potential 12/742 76/18722 4.14886421755591e-05 0.00194219600300617 AKAP9/CAV1/GJA1/DSP/DSG2/DSC2/ANK3/GJA5/DLG1/ATP1A1/CALM1/YWHAE 12 GO:0010632 regulation of epithelial cell migration 27/742 292/18722 4.16746510766507e-05 0.00194219600300617 NRP2/GRN/RHOB/MET/SERPINF1/MACF1/PLPP3/RTN4/NRP1/TACSTD2/ATP2B4/NR2F2/CALR/PFN1/TMSB4X/ANXA1/LGMN/NF1/EMC10/FOXP1/GATA3/MARVELD3/HSPB1/RHOA/RAB11A/ANXA3/CSNK2B 27 GO:0086004 regulation of cardiac muscle cell contraction 8/742 34/18722 4.25713855799827e-05 0.00196544527817864 AKAP9/CAV1/DSP/DSG2/DSC2/GJA5/DLG1/ATP1A1 8 GO:0110053 regulation of actin filament organization 26/742 277/18722 4.46684888385847e-05 0.00204316976724638 IQGAP2/MET/KANK1/SPTAN1/NRP1/TACSTD2/PFN1/TMSB4X/SPTBN1/SLC9A1/ACTG1/DLG1/WASF2/RASA1/ROCK1/TRIOBP/PPP1R9A/KANK4/ID1/S100A10/CDC42/ARPC3/DSTN/RHOA/CAPZB/COTL1 26 GO:0001952 regulation of cell-matrix adhesion 16/742 128/18722 4.69393194415635e-05 0.00212148217177479 LRP1/DAG1/MACF1/UTRN/IQGAP1/NRP1/FERMT1/SLC9A1/CDK6/ACTG1/NF1/PTPRA/RASA1/ROCK1/S100A10/RHOA 16 GO:0055117 regulation of cardiac muscle contraction 12/742 77/18722 4.74019187417769e-05 0.00212148217177479 AKAP9/CAV1/DSP/DSG2/DSC2/GSTO1/GJA5/SLC9A1/DLG1/ATP1A1/CALM1/CALM2 12 GO:0045216 cell-cell junction organization 21/742 200/18722 4.76689313900813e-05 0.00212148217177479 CDH1/CLDN4/SVEP1/PLEC/CAV1/GJA1/DSP/DSG2/PKN2/LSR/DLG5/JAM3/GJA5/ACTG1/CTNND1/DLG1/ROCK1/MARVELD3/TLN1/CDC42/RHOA 21 GO:0003018 vascular process in circulatory system 25/742 263/18722 5.06045364745696e-05 0.00219945120284399 LRP2/EGFR/ATP2B1/LRP1/SLC2A1/PLEC/TFRC/CAV1/SLC38A1/SLC38A2/GJA1/SLC1A5/SOD3/SLC19A1/SLC6A4/ATP2B4/GJA5/SLC16A12/ADRB1/ROCK1/SLC5A3/ADM/SLC16A1/GPX1/RHOA 25 GO:0002026 regulation of the force of heart contraction 7/742 26/18722 5.07565662194766e-05 0.00219945120284399 GAA/CAV1/ATP2B4/SLC9A1/ADRB1/ATP1A1/ADM 7 GO:0060669 embryonic placenta morphogenesis 7/742 26/18722 5.07565662194766e-05 0.00219945120284399 SPINT1/SPINT2/ZFP36L1/BMP7/ST14/ADM/IGF2 7 GO:0051098 regulation of binding 31/742 363/18722 5.35949036281426e-05 0.00230225064280891 JUN/LRP1/APP/LRPAP1/MET/CAV1/TGFBR3/C4orf3/NRP1/PTPRF/ISL1/TMSB4X/CCPG1/EIF4G1/ROCK1/TCF7L2/NSD1/DDIT3/RSF1/TXN/NFKBIA/CALM1/GATA3/ID1/PARP1/RAN/S100A10/HES1/CDC42/CALM2/CSNK2B 31 GO:0050678 regulation of epithelial cell proliferation 32/742 381/18722 5.62094839965913e-05 0.00239374871502725 EGFR/NRP2/GRN/LAMB1/LAMC1/SERPINF1/CAV1/TGFBR3/GJA1/PRKDC/ZFP36L1/FLT1/RTN4/NRP1/ISL1/NR2F2/CDK6/NF1/MYDGF/MAGED1/DLG1/EMC10/TCF7L2/SRSF6/KDM5B/GATA3/MARVELD3/GPX1/ID1/HES1/CDC42/IGF2 32 GO:0032535 regulation of cellular component size 32/742 382/18722 5.90928413270302e-05 0.00245711672681969 LRP1/GOLGA4/SEMA6A/IQGAP2/KCNN4/MACF1/KANK1/SLC12A9/SEMA6D/RTN4/PPP1R15A/SPTAN1/NRP1/NPM1/PFN1/TMSB4X/SPTBN1/DLG1/WASF2/RASA1/TRIOBP/PPP1R9A/KANK4/HP1BP3/RB1CC1/CLN3/ARPC3/DSTN/RHOA/RAB11A/CAPZB/COTL1 32 GO:0010720 positive regulation of cell development 27/742 298/18722 5.91896539456565e-05 0.00245711672681969 LRP2/EGFR/SPINT1/LRP1/DAG1/GOLGA4/P4HB/SERPINF1/MACF1/UFL1/IL6ST/PRKDC/ATP6AP1/NRP1/CALR/MME/CUX1/GLI3/MAN2A1/TRIOBP/DHX36/OBSL1/S100A10/HES1/CDC42/TGM2/RAB11A 27 GO:0048511 rhythmic process 27/742 298/18722 5.91896539456565e-05 0.00245711672681969 JUN/EGFR/HSPA5/JUND/CLDN4/SERPINF1/MYCBP2/LGR4/ADAMTS1/EGR1/PRKDC/SLC6A4/ZFHX3/NAGLU/DDB1/MAGED1/ADRB1/KDM5A/NCOR1/GNAQ/USP9X/KDM5B/HUWE1/DDX5/NR2F6/ID1/SIAH2 27 GO:0098911 regulation of ventricular cardiac muscle cell action potential 5/742 12/18722 6.05636609236271e-05 0.00249320404135598 CAV1/DSP/DSG2/DSC2/DLG1 5 GO:0006446 regulation of translational initiation 12/742 79/18722 6.14454899660539e-05 0.00250860099530832 RPL13A/PPP1R15A/NPM1/TPR/EIF4G1/EIF3H/EIF2AK4/LARP1/HSPB1/EIF1/EIF4H/EIF4B 12 GO:0071383 cellular response to steroid hormone stimulus 21/742 204/18722 6.36801552288752e-05 0.00257852431828396 EGFR/ATP2B1/SERPINF1/UFL1/ZFP36L1/BMP7/ISL1/CALR/ESRRA/ANXA1/ARID1A/ATP1A1/DDX17/NCOR1/FOXP1/DDX5/PARP1/PTGES3/RHOA/UBE2L3/LBH 21 GO:0051101 regulation of DNA binding 15/742 118/18722 6.6082840336765e-05 0.00261069592413657 JUN/ISL1/TMSB4X/NSD1/DDIT3/RSF1/TXN/NFKBIA/CALM1/GATA3/ID1/PARP1/HES1/CALM2/CSNK2B 15 GO:0006491 N-glycan processing 6/742 19/18722 6.6157529983465e-05 0.00261069592413657 GANAB/MAN2A1/MAN1A2/FUT8/GNPTAB/PRKCSH 6 GO:0010498 proteasomal protein catabolic process 38/742 490/18722 6.65234458607863e-05 0.00261069592413657 HSP90B1/HSPA5/UFL1/NHLRC3/CAV1/CCDC47/CALR/TMEM259/HSPA1A/UBXN4/DDB1/OS9/CANX/PMAIP1/HSPA1B/DNAJB14/FAF2/NEMF/HECTD1/EIF3H/DDIT3/PSMD1/GNA12/KLHL42/PCBP2/HUWE1/TBL1X/GPX1/SKP1/SIAH2/HM13/BCAP31/SIAH1/DDA1/ANAPC11/UBE2C/PSME2/SDCBP 38 GO:0035637 multicellular organismal signaling 18/742 160/18722 6.65886004941716e-05 0.00261069592413657 AKAP9/ATP2B1/PLEC/CAV1/GJA1/DSP/DSG2/DSC2/ANK3/JAM3/ATP2B4/ISL1/GJA5/SLC9A1/ATP1A1/CALM1/CALM2/YWHAE 18 GO:0072659 protein localization to plasma membrane 26/742 284/18722 6.78824661466962e-05 0.00264046758082424 EGFR/LRP1/CDH1/LAMA5/ITGB1/GOLGA4/MACF1/BSG/ANK3/ATP2B4/ARL6IP5/TMEM59/SPTBN1/CD81/KIF5B/DLG1/ROCK1/TPBG/HECTD1/VAMP2/KRT18/CLTC/CLN3/S100A10/MYL12A/RAB11A 26 GO:0009314 response to radiation 36/742 456/18722 7.16990339296973e-05 0.00275018830638056 JUN/EGFR/FOS/HSPA5/APP/ITGB1/JUND/RHOB/DUSP1/RPL26/EGR1/PRKDC/LRP5/NPM1/MME/ANXA1/DDB1/NF1/NIPBL/NMT1/TP53I13/CDS1/TMEM109/GNAQ/SDF4/DHX36/EIF2AK4/TXN/CIRBP/GATA3/NR2F6/GPX1/PARP1/ADIRF/DYNLRB1/YY1 36 GO:1900024 regulation of substrate adhesion-dependent cell spreading 10/742 57/18722 7.18166582030551e-05 0.00275018830638056 FBLN1/P4HB/KANK1/NRP1/TACSTD2/CALR/ACTN4/TRIOBP/S100A10/CDC42 10 GO:0060993 kidney morphogenesis 13/742 93/18722 7.46602279748491e-05 0.00283708866304427 LAMA5/LGR4/SOX4/PBX1/FRAS1/BMP7/TACSTD2/GLI3/MAGED1/DLG1/IRX2/GATA3/HES1 13 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 9/742 47/18722 8.09293928599802e-05 0.0030518412269336 JUN/HSPA5/EGR1/HSPA1A/ATF6/DDIT3/CITED2/EPAS1/DNAJB1 9 GO:1903522 regulation of blood circulation 24/742 256/18722 8.83285342459044e-05 0.00325867246126132 EGFR/AKAP9/ATP2B1/GAA/CAV1/GJA1/DSP/DSG2/DSC2/GSTO1/ATP2B4/ISL1/GJA5/SLC9A1/ADRB1/DLG1/ATP1A1/ADM/CALM1/EPAS1/CYP2J2/RHOA/CALM2/YWHAE 24 GO:0001838 embryonic epithelial tube formation 15/742 121/18722 8.83931396374527e-05 0.00325867246126132 LRP2/SPINT1/SPINT2/SOX4/BMP7/LMO4/FOLR1/PFN1/BRD2/ST14/IRX2/HECTD1/ADM/CITED2/GATA3 15 GO:0045931 positive regulation of mitotic cell cycle 15/742 121/18722 8.83931396374527e-05 0.00325867246126132 EGFR/APP/ADAMTS1/PBX1/PKN2/PPP1R10/BRD4/ANXA1/LGMN/EIF4G1/USP22/HES1/RAB11A/ANAPC11/UBE2C 15 GO:1905897 regulation of response to endoplasmic reticulum stress 12/742 82/18722 8.91951188256982e-05 0.00326388064443666 HSPA5/UFL1/ERP29/CAV1/PPP1R15A/TMEM259/HSPA1A/PMAIP1/ATF6/SERINC3/DDIT3/BCAP31 12 GO:1900115 extracellular regulation of signal transduction 5/742 13/18722 9.52079420953794e-05 0.00343304550329324 FBN2/FBN1/CD46/LRPAP1/LTBP1 5 GO:1900116 extracellular negative regulation of signal transduction 5/742 13/18722 9.52079420953794e-05 0.00343304550329324 FBN2/FBN1/CD46/LRPAP1/LTBP1 5 GO:0022613 ribonucleoprotein complex biogenesis 36/742 463/18722 9.75445172288064e-05 0.00349181097906017 RPS21/RPLP0/RPL13A/RPL23A/RPS6/RPS16/RPL6/RPL14/SF1/EIF3A/RPL7/RPS25/RPL24/RPL26/PRKDC/SCAF11/NPM1/SRSF5/RPL3/LUC7L3/DDX17/RPS17/EIF3H/SRSF6/CELF1/SF3B1/SNRPD2/ADAR/RAN/PTGES3/EIF2S2/EIF3F/EIF4H/SNRPC/EIF3I/EIF4B 36 GO:0071241 cellular response to inorganic substance 22/742 226/18722 9.91745606234837e-05 0.0035167977399579 JUN/EGFR/FOS/HSPA5/CDH1/APP/JUND/SERPINF1/FOSB/FUS/IQGAP1/ATRX/ANK3/CALR/LGMN/NCSTN/JUNB/MTR/SYT7/PARP1/HSD17B1/CACYBP 22 GO:0097242 amyloid-beta clearance 8/742 38/18722 9.96663327113575e-05 0.0035167977399579 LRP2/LRP1/LRPAP1/IGF1R/MME/ROCK1/CLTC/RAB11A 8 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 33/742 412/18722 0.000108049765532136 0.00378557334559399 HSP90B1/HSPA5/UFL1/NHLRC3/CAV1/CCDC47/CALR/HSPA1A/UBXN4/DDB1/OS9/CANX/HSPA1B/DNAJB14/FAF2/NEMF/HECTD1/EIF3H/DDIT3/PSMD1/GNA12/KLHL42/PCBP2/HUWE1/TBL1X/SKP1/SIAH2/BCAP31/SIAH1/DDA1/ANAPC11/UBE2C/SDCBP 33 GO:0031102 neuron projection regeneration 10/742 60/18722 0.000112658723399958 0.00391925418025205 LRP1/GRN/DAG1/PTPRF/JAM3/ISL1/FOLR1/MTR/ADM/NREP 10 GO:0009409 response to cold 9/742 49/18722 0.000113681259265339 0.00392249840539698 ATP2B1/FOS/SLC9A1/ADRB1/ACADVL/ADM/EIF2AK4/CIRBP/NFKBIA 9 GO:0071248 cellular response to metal ion 20/742 197/18722 0.000114340034489305 0.00392249840539698 JUN/EGFR/FOS/HSPA5/CDH1/APP/JUND/SERPINF1/FOSB/FUS/IQGAP1/ANK3/CALR/LGMN/NCSTN/JUNB/SYT7/PARP1/HSD17B1/CACYBP 20 GO:0061138 morphogenesis of a branching epithelium 19/742 182/18722 0.000116313842696572 0.00396269229600735 SPINT1/LAMA5/DAG1/MET/SPINT2/LGR4/PBX1/DLG5/LRP5/NRP1/BMP7/TACSTD2/GLI3/MAGED1/DLG1/ST14/ADM/KDM5B/TGM2 19 GO:1903115 regulation of actin filament-based movement 8/742 39/18722 0.000121073589780576 0.00409659954463043 AKAP9/CAV1/DSP/DSG2/DSC2/GJA5/DLG1/ATP1A1 8 GO:0030111 regulation of Wnt signaling pathway 28/742 328/18722 0.000122243313933343 0.004108040617896 EGFR/LRP1/APP/LGR5/MACF1/KANK1/WLS/CAV1/RNF43/LGR4/SOX4/EGR1/TLE4/PLPP3/ISL1/FERMT1/FOLR1/GLI3/ZNRF3/ATP6AP2/CTNND1/TPBG/TCF7L2/GNAQ/DDIT3/TBL1X/SIAH2/NOTUM 28 GO:0045056 transcytosis 6/742 21/18722 0.000123628322120879 0.00412651291403474 LRP2/LRP1/LRPAP1/IGF1R/CLTC/RAB11A 6 GO:0001656 metanephros development 12/742 85/18722 0.000127104357240376 0.00421406392461382 FBN1/LGR4/EGR1/DLG5/FRAS1/BMP7/GLI3/NF1/NIPBL/IRX2/GATA3/HES1 12 GO:0051258 protein polymerization 26/742 296/18722 0.000133710730757574 0.00440354006628276 AKAP9/IQGAP2/MET/CLIP1/KANK1/SPTAN1/PFN1/TMSB4X/SPTBN1/HSPA1A/DLG1/DIAPH1/WASF2/RASA1/HSPA1B/TRIOBP/PPP1R9A/KANK4/MSRB2/ARPC3/GPX4/RHOA/UBE2C/CAPZB/VDAC2/COTL1 26 GO:0031333 negative regulation of protein-containing complex assembly 16/742 140/18722 0.000138328513034997 0.00452544936684031 HSPA5/RPL13A/KANK1/SPTAN1/JAM3/LMO4/ISL1/PFN1/TMSB4X/SPTBN1/TRIOBP/KANK4/CDC42/CAPZB/VDAC2/LCMT1 16 GO:0071214 cellular response to abiotic stimulus 28/742 331/18722 0.000142594714932497 0.00460403850827799 EGFR/HSPA5/SLC2A1/DAG1/RHOB/PLEC/RPL26/SLC38A2/GJA1/EGR1/ZFP36L1/NPM1/TMEM150C/MME/SLC9A1/DDB1/NIPBL/NMT1/ATP1A1/TMEM109/DHX36/EIF2AK4/GATA3/PARP1/CLN3/ADIRF/YY1/EFHD1 28 GO:0104004 cellular response to environmental stimulus 28/742 331/18722 0.000142594714932497 0.00460403850827799 EGFR/HSPA5/SLC2A1/DAG1/RHOB/PLEC/RPL26/SLC38A2/GJA1/EGR1/ZFP36L1/NPM1/TMEM150C/MME/SLC9A1/DDB1/NIPBL/NMT1/ATP1A1/TMEM109/DHX36/EIF2AK4/GATA3/PARP1/CLN3/ADIRF/YY1/EFHD1 28 GO:0032271 regulation of protein polymerization 22/742 232/18722 0.000145320915782588 0.00466159301276613 AKAP9/IQGAP2/MET/CLIP1/KANK1/SPTAN1/PFN1/TMSB4X/SPTBN1/HSPA1A/DLG1/WASF2/RASA1/HSPA1B/TRIOBP/PPP1R9A/KANK4/ARPC3/RHOA/CAPZB/VDAC2/COTL1 22 GO:0003151 outflow tract morphogenesis 11/742 74/18722 0.000150798325683655 0.00474486451514175 LRP2/NRP2/TGFBR3/NRP1/BMP7/ISL1/GJA5/FOLR1/NIPBL/CITED2/HES1 11 GO:0007040 lysosome organization 11/742 74/18722 0.000150798325683655 0.00474486451514175 GRN/GAA/NAGLU/HOOK2/ATP6AP2/SYT7/MBTPS1/TMEM165/GNPTAB/CLN3/HEXB 11 GO:0080171 lytic vacuole organization 11/742 74/18722 0.000150798325683655 0.00474486451514175 GRN/GAA/NAGLU/HOOK2/ATP6AP2/SYT7/MBTPS1/TMEM165/GNPTAB/CLN3/HEXB 11 GO:0007160 cell-matrix adhesion 22/742 233/18722 0.000154630333008118 0.00483152320009241 ITGB4/LRP1/ITGAV/ITGB1/DAG1/BCAM/MACF1/UTRN/IQGAP1/NRP1/JAM3/FERMT1/SLC9A1/CDK6/ITGB5/ACTG1/NF1/PTPRA/RASA1/ROCK1/S100A10/RHOA 22 GO:0035051 cardiocyte differentiation 17/742 156/18722 0.000155739854027716 0.00483152320009241 EGFR/ITGB1/PLEC/TGFBR3/BMP7/ISL1/CALR/FOLR1/SLC9A1/AKAP13/DHX36/CITED2/OBSL1/HES1/YY1/PDCD4/CACYBP 17 GO:1990778 protein localization to cell periphery 28/742 333/18722 0.000157793260214186 0.00483152320009241 EGFR/LRP1/CDH1/LAMA5/ITGB1/DAG1/GOLGA4/MACF1/BSG/CAV1/ANK3/ATP2B4/ARL6IP5/TMEM59/SPTBN1/CD81/KIF5B/DLG1/ROCK1/TPBG/HECTD1/VAMP2/KRT18/CLTC/CLN3/S100A10/MYL12A/RAB11A 28 GO:0060840 artery development 13/742 100/18722 0.000158661464778219 0.00483152320009241 LRP2/LRP1/ADAMTS6/SOX4/NRP1/GJA5/FOLR1/GLI3/NF1/HECTD1/CITED2/HES1/HPGD 13 GO:0110020 regulation of actomyosin structure organization 13/742 100/18722 0.000158661464778219 0.00483152320009241 MET/NRP1/TACSTD2/PFN1/SLC9A1/ACTG1/AKAP13/WASF2/ROCK1/PPP1R9A/S100A10/CDC42/RHOA 13 GO:0150104 transport across blood-brain barrier 12/742 87/18722 0.000159420704780377 0.00483152320009241 LRP2/LRP1/SLC2A1/TFRC/SLC38A1/SLC38A2/SLC1A5/SLC19A1/ATP2B4/SLC16A12/SLC5A3/SLC16A1 12 GO:0007163 establishment or maintenance of cell polarity 21/742 218/18722 0.000163976716900741 0.00491965946124424 ITGB1/RHOB/SPINT2/KANK1/GJA1/DLG5/DST/JAM3/FERMT1/FRMD4A/SLC9A1/FAT1/DLG1/ROCK1/GATA3/RHOBTB3/DOCK8/HES1/CDC42/RHOA/DYNLT1 21 GO:0060713 labyrinthine layer morphogenesis 6/742 22/18722 0.000164320609535486 0.00491965946124424 SPINT1/SPINT2/ZFP36L1/BMP7/ST14/ADM 6 GO:0002244 hematopoietic progenitor cell differentiation 14/742 114/18722 0.000166492645025721 0.00495466064112687 PRRC2C/N4BP2L2/RBM47/UFL1/SOX4/PRKDC/FLT1/JAM3/CHD2/DHX36/CITED2/GATA3/ADAR/HES1 14 GO:0061333 renal tubule morphogenesis 11/742 75/18722 0.000170490587338827 0.00504325449972338 LAMA5/LGR5/LGR4/PBX1/TACSTD2/GLI3/MAGED1/DLG1/IRX2/GATA3/HES1 11 GO:0042063 gliogenesis 26/742 301/18722 0.000174904049308431 0.00513347562647598 LRP2/EGFR/SPINT1/ITGB4/LRP1/GRN/ADGRG1/APP/LAMB1/DAG1/PLEC/UFL1/SOX4/IL6ST/RTN4/ANXA1/CDK6/GLI3/GPC1/NF1/NCSTN/S100A9/ERBB3/HEXB/HES1/RHOA 26 GO:0098869 cellular oxidant detoxification 13/742 101/18722 0.000175618903011021 0.00513347562647598 MGST3/SOD3/GSTO1/BMP7/GPX3/S100A9/GPX8/TXN/PRDX6/GPX1/PRDX4/GPX4/HBA2 13 GO:0031103 axon regeneration 9/742 52/18722 0.000183098508791984 0.00528951247621286 LRP1/GRN/DAG1/PTPRF/JAM3/ISL1/FOLR1/MTR/NREP 9 GO:0060147 regulation of posttranscriptional gene silencing 9/742 52/18722 0.000183098508791984 0.00528951247621286 EGFR/NEAT1/KCNQ1OT1/EIF4G1/TNRC6B/PUM1/NCOR1/DDX5/ADAR 9 GO:0090068 positive regulation of cell cycle process 22/742 236/18722 0.000185802048078835 0.00533640765993862 EGFR/APP/DYNC1H1/ATRX/ADAMTS1/PBX1/PKN2/LRP5/PPP1R10/NPM1/TPR/BRD4/ANXA1/PHIP/EIF4G1/CDC42/RHOA/IGF2/RAB11A/ANAPC11/UBE2C/RANBP1 22 GO:0072028 nephron morphogenesis 11/742 76/18722 0.000192321685751072 0.0053927521723673 LAMA5/LGR4/PBX1/BMP7/TACSTD2/GLI3/MAGED1/DLG1/IRX2/GATA3/HES1 11 GO:0052547 regulation of peptidase activity 35/742 461/18722 0.000192354577005766 0.0053927521723673 ITIH5/GAPDH/APLP2/SPINT1/FBLN1/LRP1/GRN/APP/CLDN4/CRIM1/CTSD/SPINT2/SERPINF1/CAV1/DHCR24/SERPINH1/POR/ARL6IP5/ASPH/LGMN/NCSTN/S100A9/PMAIP1/ROCK1/CST3/TIMP3/GPX1/PCOLCE2/TFPI2/SIAH2/BCAP31/SERPINB9/SERPINB1/RHOA/PSME2 35 GO:0062197 cellular response to chemical stress 28/742 337/18722 0.000192594824585279 0.0053927521723673 JUN/EGFR/FOS/SLC2A1/P4HB/RHOB/MET/PLEC/CAV1/SOD3/ZFP36L1/BMP7/ARL6IP5/HSPA1A/ANXA1/HSPA1B/PPIA/FUT8/GPX8/DDIT3/TXN/EPAS1/HSPB1/GPX1/PARP1/CLN3/DHRS2/EFHD1 28 GO:0001841 neural tube formation 13/742 102/18722 0.000194109353849713 0.0053927521723673 LRP2/SPINT1/SPINT2/SOX4/BMP7/LMO4/FOLR1/PFN1/BRD2/ST14/HECTD1/ADM/CITED2 13 GO:0060828 regulation of canonical Wnt signaling pathway 23/742 253/18722 0.000194115497335229 0.0053927521723673 EGFR/LGR5/KANK1/WLS/CAV1/LGR4/SOX4/EGR1/TLE4/ISL1/FERMT1/FOLR1/GLI3/ZNRF3/ATP6AP2/CTNND1/TPBG/TCF7L2/GNAQ/DDIT3/TBL1X/SIAH2/NOTUM 23 GO:0060070 canonical Wnt signaling pathway 26/742 303/18722 0.000194313742243194 0.0053927521723673 EGFR/LGR5/KANK1/WLS/CAV1/LGR4/SOX4/EGR1/TLE4/PLPP3/LRP5/ISL1/FERMT1/FOLR1/GLI3/ZNRF3/ATP6AP2/CTNND1/TPBG/TCF7L2/GNAQ/DDIT3/GATA3/TBL1X/SIAH2/NOTUM 26 GO:0032507 maintenance of protein location in cell 10/742 64/18722 0.000196274444937739 0.00541673607816999 HSPA5/CAV1/GJA1/ANK3/TMSB4X/VPS13C/OS9/GPAA1/TXN/SKP1 10 GO:0042176 regulation of protein catabolic process 31/742 391/18722 0.000207290398994499 0.00563720339510899 LRP2/EGFR/EEF1A1/LRP1/CDH1/CTSC/MYCBP2/UFL1/CAV1/GJA1/RPL23/CTSA/TMEM259/HSPA1A/CD81/DDB1/HSPA1B/ROCK1/CST3/TIMP3/HECTD1/EIF3H/PSMD1/GNA12/HUWE1/GPX1/BCAP31/ATRAID/DDA1/PSME2/SDCBP 31 GO:1901660 calcium ion export 5/742 15/18722 0.000207925810157709 0.00563720339510899 ATP2B1/ATP2B4/CALM1/CALM2/YWHAE 5 GO:0048863 stem cell differentiation 20/742 206/18722 0.000209556853780419 0.00563720339510899 NRP2/LAMA5/SEMA6A/N4BP2L2/UFL1/SEMA6D/PRKDC/NRP1/BMP7/TACSTD2/ISL1/FOLR1/LTBP3/PUM1/CHD2/DHX36/CITED2/KRT18/HES1/LBH 20 GO:0043254 regulation of protein-containing complex assembly 33/742 427/18722 0.000210276000042101 0.00563720339510899 AKAP9/HSPA5/RPL13A/IQGAP2/MET/CLIP1/KANK1/TFRC/SPTAN1/JAM3/LMO4/ISL1/FERMT1/PFN1/TMSB4X/SPTBN1/HSPA1A/EIF4G1/DLG1/WASF2/RASA1/HSPA1B/TRIOBP/PPP1R9A/KANK4/PARP1/CDC42/ARPC3/RHOA/CAPZB/VDAC2/LCMT1/COTL1 33 GO:0010644 cell communication by electrical coupling 7/742 32/18722 0.000211097239419805 0.00563720339510899 CAV1/GJA1/ANK3/GJA5/ATP1A1/CALM1/CALM2 7 GO:0043620 regulation of DNA-templated transcription in response to stress 9/742 53/18722 0.000212898512092162 0.00563720339510899 JUN/HSPA5/EGR1/HSPA1A/ATF6/DDIT3/CITED2/EPAS1/DNAJB1 9 GO:0060966 regulation of gene silencing by RNA 9/742 53/18722 0.000212898512092162 0.00563720339510899 EGFR/NEAT1/KCNQ1OT1/EIF4G1/TNRC6B/PUM1/NCOR1/DDX5/ADAR 9 GO:0097193 intrinsic apoptotic signaling pathway 25/742 288/18722 0.000214533246615484 0.00563720339510899 TPT1/P4HB/ERP29/CAV1/MIF/RPL26/PRKDC/PPP1R15A/ARL6IP5/HSPA1A/ENO1/S100A9/PMAIP1/TMEM109/SERINC3/PPIA/DDIT3/DDX5/HSPB1/GPX1/PARP1/BCAP31/SIAH1/VDAC2/EIF5A 25 GO:1903311 regulation of mRNA metabolic process 25/742 288/18722 0.000214533246615484 0.00563720339510899 SON/SF1/FUS/RBM39/ZFP36L1/NPM1/TNRC6A/RBM25/TRA2B/TNRC6B/YBX1/ROCK1/PUM1/HNRNPA1/DDX17/SRSF7/DHX36/SRSF6/CELF1/LARP1/CIRBP/PRDX6/DDX5/HNRNPC/MBNL3 25 GO:0006979 response to oxidative stress 34/742 446/18722 0.0002190431319767 0.00572525434902063 JUN/EGFR/FOS/APP/LDHA/P4HB/RHOB/MET/DUSP1/DHCR24/SOD3/BMP7/ARL6IP5/HSPA1A/ANXA1/GPX3/BTG1/TRA2B/HSPA1B/PPIA/FUT8/PON2/GPX8/MSRB2/TXN/PRDX6/EPAS1/HSPB1/GPX1/PARP1/PRDX4/DHRS2/GPX4/HBA2 34 GO:0010634 positive regulation of epithelial cell migration 18/742 176/18722 0.000225484960258154 0.00586260896671199 NRP2/GRN/RHOB/MET/PLPP3/RTN4/NRP1/CALR/PFN1/TMSB4X/ANXA1/LGMN/EMC10/FOXP1/GATA3/HSPB1/RAB11A/ANXA3 18 GO:0003205 cardiac chamber development 17/742 161/18722 0.000228157029494786 0.00590102474190704 LRP2/NRP2/ADAMTS6/TGFBR3/SOX4/DSP/TRIP11/ADAMTS1/NRP1/BMP7/LMO4/ISL1/GJA5/HECTD1/CITED2/GATA3/HES1 17 GO:0072175 epithelial tube formation 15/742 132/18722 0.000235931982826761 0.00607033330814687 LRP2/SPINT1/SPINT2/SOX4/BMP7/LMO4/FOLR1/PFN1/BRD2/ST14/IRX2/HECTD1/ADM/CITED2/GATA3 15 GO:0016331 morphogenesis of embryonic epithelium 16/742 147/18722 0.000244190492526697 0.00624766236717061 LRP2/SPINT1/LAMA5/SPINT2/SOX4/BMP7/LMO4/FOLR1/PFN1/BRD2/ST14/IRX2/HECTD1/ADM/CITED2/GATA3 16 GO:0051492 regulation of stress fiber assembly 12/742 91/18722 0.000245497760181104 0.00624766236717061 MET/NRP1/TACSTD2/PFN1/SLC9A1/ACTG1/WASF2/ROCK1/PPP1R9A/S100A10/CDC42/RHOA 12 GO:0070839 metal ion export 9/742 54/18722 0.000246618251335682 0.00624766236717061 ATP2B1/ATP2B4/SLC9A1/SLC40A1/DLG1/ATP1A1/CALM1/CALM2/YWHAE 9 GO:0051893 regulation of focal adhesion assembly 10/742 66/18722 0.000254597945311573 0.00638433426314299 LRP1/MACF1/IQGAP1/NRP1/SLC9A1/ACTG1/PTPRA/ROCK1/S100A10/RHOA 10 GO:0090109 regulation of cell-substrate junction assembly 10/742 66/18722 0.000254597945311573 0.00638433426314299 LRP1/MACF1/IQGAP1/NRP1/SLC9A1/ACTG1/PTPRA/ROCK1/S100A10/RHOA 10 GO:0010595 positive regulation of endothelial cell migration 15/742 133/18722 0.000256396469288644 0.00639696241558536 NRP2/GRN/RHOB/MET/PLPP3/NRP1/CALR/TMSB4X/ANXA1/LGMN/EMC10/FOXP1/GATA3/HSPB1/ANXA3 15 GO:0032231 regulation of actin filament bundle assembly 13/742 105/18722 0.000259928313521791 0.00645249180300325 MET/NRP1/TACSTD2/PFN1/SLC9A1/ACTG1/WASF2/ROCK1/PPP1R9A/ID1/S100A10/CDC42/RHOA 13 GO:0070997 neuron death 29/742 361/18722 0.000263850513486088 0.00648716551664485 JUN/GAPDH/FOS/HSPA5/LRP1/GRN/APP/SERPINF1/DHCR24/EGR1/NRP1/ISL1/ARL6IP5/TMEM259/SLC9A1/LGMN/NF1/NCSTN/EIF4G1/RASA1/ERBB3/DDIT3/GATA3/GPX1/PARP1/CLN3/SIAH1/CDC42/RHOA 29 GO:0035148 tube formation 16/742 148/18722 0.000263951471426238 0.00648716551664485 LRP2/SPINT1/SPINT2/SOX4/BMP7/LMO4/FOLR1/PFN1/BRD2/ST14/IRX2/HECTD1/ADM/CITED2/GATA3/TGM2 16 GO:0001508 action potential 15/742 134/18722 0.000278374035042145 0.00680776105499106 AKAP9/CAV1/GJA1/DSP/DSG2/DSC2/ANK3/GJA5/SLC9A1/DLG1/ATP1A1/GNAQ/CALM1/CLN3/YWHAE 15 GO:0098900 regulation of action potential 9/742 55/18722 0.000284648023580158 0.00685199865392522 AKAP9/CAV1/DSP/DSG2/DSC2/GJA5/SLC9A1/DLG1/CALM1 9 GO:0051592 response to calcium ion 16/742 149/18722 0.000285081624581977 0.00685199865392522 EGFR/FOS/HSPA5/JUND/FOSB/FUS/DUSP1/CAV1/IQGAP1/LGMN/NCSTN/JUNB/SYT7/CALM1/CALM2/CACYBP 16 GO:0030038 contractile actin filament bundle assembly 13/742 106/18722 0.000285731117957206 0.00685199865392522 MET/NRP1/TACSTD2/PFN1/SLC9A1/ITGB5/ACTG1/WASF2/ROCK1/PPP1R9A/S100A10/CDC42/RHOA 13 GO:0043149 stress fiber assembly 13/742 106/18722 0.000285731117957206 0.00685199865392522 MET/NRP1/TACSTD2/PFN1/SLC9A1/ITGB5/ACTG1/WASF2/ROCK1/PPP1R9A/S100A10/CDC42/RHOA 13 GO:0090150 establishment of protein localization to membrane 23/742 260/18722 0.000288592192647353 0.00686561670795294 EGFR/HSPA5/TCAF1/GOLGA4/MACF1/SEC62/NACA/SIL1/ANK3/CCDC47/SPTBN1/EMC1/STOM/EMC10/NMT1/VAMP2/SEC61A1/SEC63/CALM1/KRT18/CLN3/RAB11A/SDCBP 23 GO:0001732 formation of cytoplasmic translation initiation complex 5/742 16/18722 0.000292608307244243 0.00686561670795294 EIF3A/EIF3H/EIF2S2/EIF3F/EIF3I 5 GO:0019081 viral translation 5/742 16/18722 0.000292608307244243 0.00686561670795294 EIF3A/EIF2AK4/PCBP2/EIF3F/SSB 5 GO:0060711 labyrinthine layer development 8/742 44/18722 0.000292858168525193 0.00686561670795294 SPINT1/SPINT2/ZFP36L1/BMP7/JUNB/ST14/ADM/HES1 8 GO:0048880 sensory system development 30/742 381/18722 0.000293248001088678 0.00686561670795294 FBN2/ATP2B1/FBN1/EFEMP1/TENM3/SERPINF1/RPL24/PBX1/FLT1/LRP5/NAGLU/NRP1/BMP7/ATP2B4/ISL1/CRYBG3/GLI3/NF1/FAT1/DLG1/MAN2A1/NIPBL/TUG1/SMOC1/ATF6/KDM5B/CITED2/GATA3/OBSL1/YY1 30 GO:0043409 negative regulation of MAPK cascade 18/742 180/18722 0.000297772069199041 0.00693865104643047 FBLN1/DAG1/SEMA6A/EIF3A/DUSP1/CAV1/DUSP6/IGF1R/BMP7/NF1/ASH1L/DLG1/DUSP9/TIMP3/NCOR1/PPIA/MARVELD3/PDCD4 18 GO:0036503 ERAD pathway 13/742 107/18722 0.000313688471544169 0.00727323887222154 HSP90B1/HSPA5/CAV1/CCDC47/CALR/TMEM259/UBXN4/OS9/CANX/DNAJB14/FAF2/HM13/BCAP31 13 GO:0098656 anion transmembrane transport 22/742 245/18722 0.000315075530092188 0.00727323887222154 LRP2/SLC26A2/TCAF1/ITGB1/SLC12A9/SLC3A2/SLC43A2/GJA1/SLC1A5/SLC19A1/SLC13A4/GABRE/ARL6IP5/SLC38A9/FOLR1/SLC9A1/SLC16A12/PCYOX1/SLC35B4/SLC16A1/VDAC1/VDAC2 22 GO:0031122 cytoplasmic microtubule organization 9/742 56/18722 0.000327403445252474 0.00752266520719638 DYNC1H1/CLIP1/DST/HOOK2/DLG1/PCM1/KPNB1/RHOA/RAB11A 9 GO:0048592 eye morphogenesis 16/742 151/18722 0.000331763670584282 0.00755795431857444 FBN2/FBN1/EFEMP1/TENM3/LRP5/NAGLU/BMP7/GLI3/NF1/FAT1/MAN2A1/NIPBL/TUG1/CITED2/OBSL1/YY1 16 GO:0014020 primary neural tube formation 12/742 94/18722 0.000333529158188103 0.00755795431857444 LRP2/SPINT1/SPINT2/BMP7/LMO4/FOLR1/PFN1/BRD2/ST14/HECTD1/ADM/CITED2 12 GO:1902414 protein localization to cell junction 12/742 94/18722 0.000333529158188103 0.00755795431857444 DAG1/DSP/LSR/DLG5/JAM3/KIF5B/ACTG1/DLG1/VAMP2/MARVELD3/HSPB1/RAB11A 12 GO:0043588 skin development 23/742 263/18722 0.000340150296211807 0.00764292466646825 EGFR/ITGB4/LAMA5/ITGA6/CLDN4/MET/LGR5/PLEC/LGR4/DHCR24/DSP/ZFP36L1/LSR/FRAS1/FERMT1/ANXA1/ASH1L/ROCK1/ST14/NCOA3/ASAH1/SRSF6/PTGES3 23 GO:0060968 regulation of gene silencing 11/742 81/18722 0.000340373163284011 0.00764292466646825 EGFR/NEAT1/KCNQ1OT1/MPHOSPH8/TPR/EIF4G1/TNRC6B/PUM1/NCOR1/DDX5/ADAR 11 GO:0035272 exocrine system development 8/742 45/18722 0.000343964228264444 0.00765397877309168 LAMA5/DAG1/WLS/NRP1/BMP7/CDC42/TGM2/IGF2 8 GO:0051180 vitamin transport 8/742 45/18722 0.000343964228264444 0.00765397877309168 LRP2/SLC2A1/SLC19A1/SLC52A1/FOLR1/SLC19A3/SLC52A3/SLC52A2 8 GO:0051271 negative regulation of cellular component movement 29/742 367/18722 0.000346844716783451 0.0076768650186271 FBLN1/LRP1/TCAF1/CDH1/ADGRG1/DAG1/RHOB/SPINT2/SERPINF1/KANK1/DUSP1/TGFBR3/MIF/SEMA6D/GJA1/DPP4/DLG5/TACSTD2/ATP2B4/NR2F2/CALR/MIA3/NF1/GNA12/CITED2/GATA3/MARVELD3/RHOA/CSNK2B 29 GO:0060706 cell differentiation involved in embryonic placenta development 6/742 25/18722 0.000352354000267786 0.0076768650186271 KRT19/SPINT2/KRT8/NR2F2/ST14/HECTD1 6 GO:0086064 cell communication by electrical coupling involved in cardiac conduction 6/742 25/18722 0.000352354000267786 0.0076768650186271 CAV1/GJA1/GJA5/ATP1A1/CALM1/CALM2 6 GO:1901798 positive regulation of signal transduction by p53 class mediator 6/742 25/18722 0.000352354000267786 0.0076768650186271 RPS20/RPL26/RPL23/PMAIP1/DDX5/EIF5A 6 GO:0006986 response to unfolded protein 15/742 137/18722 0.000354316847013559 0.0076768650186271 HSPA5/UFL1/SERPINH1/PPP1R15A/HSPA1A/UBXN4/OS9/HSPA1B/FAF2/CREB3L2/ATF6/MBTPS1/DDIT3/HSPB1/DNAJB1 15 GO:0007266 Rho protein signal transduction 15/742 137/18722 0.000354316847013559 0.0076768650186271 ADGRG1/ITGB1/RHOB/MET/KANK1/HACD3/NRP1/AKAP13/ROCK1/CFL1/GNA12/ARHGAP5/CDC42/RHOA/EPS8L1 15 GO:0071692 protein localization to extracellular region 29/742 368/18722 0.000362724767615539 0.0078247176944138 FBN2/EGFR/FBN1/LRP1/KCNN4/WLS/ERP29/MYH10/SOX4/GJA1/DPP4/DYNLL1/LTBP1/PDIA4/LRP5/ISL1/MIA3/FRMD4A/ANXA1/KIF5B/CANX/P3H1/TCF7L2/SYT7/PPIA/GNPTAB/SLC16A1/HMGN3/PHPT1 29 GO:0006942 regulation of striated muscle contraction 12/742 95/18722 0.000368253865270327 0.00788712365206029 AKAP9/CAV1/DSP/DSG2/DSC2/GSTO1/GJA5/SLC9A1/DLG1/ATP1A1/CALM1/CALM2 12 GO:0045665 negative regulation of neuron differentiation 10/742 69/18722 0.000368810842839256 0.00788712365206029 APP/PBX1/SLC6A4/BMP7/ISL1/CALR/GLI3/EIF2AK4/HES1/RHOA 10 GO:0010811 positive regulation of cell-substrate adhesion 14/742 123/18722 0.000370502350551904 0.00788914487813107 DAG1/ITGA6/P4HB/CCDC80/UTRN/IQGAP1/NRP1/FERMT1/CALR/CDK6/ROCK1/TRIOBP/S100A10/CDC42 14 GO:0001893 maternal placenta development 7/742 35/18722 0.00038033734981671 0.00802160963235645 BSG/GJA1/CTSV/NR2F2/ASH1L/JUNB/CITED2 7 GO:1905898 positive regulation of response to endoplasmic reticulum stress 7/742 35/18722 0.00038033734981671 0.00802160963235645 CAV1/TMEM259/PMAIP1/ATF6/SERINC3/DDIT3/BCAP31 7 GO:0009100 glycoprotein metabolic process 30/742 387/18722 0.000381594790203191 0.00802160963235645 CTSL/RPN2/GANAB/EXTL2/CHPF/GALNT11/ITM2B/TRIP11/DDOST/MANBA/TMEM59/B4GAT1/GPC1/NCSTN/MAN2A1/B3GAT3/C1GALT1/MAN1A2/CST3/MOGS/TUSC3/TCF7L2/C1GALT1C1/GXYLT1/TET2/TMEM165/FUT8/GNPTAB/PRKCSH/RPN1 30 GO:0010594 regulation of endothelial cell migration 21/742 232/18722 0.000384060339499692 0.0080392291403749 NRP2/GRN/RHOB/MET/SERPINF1/PLPP3/NRP1/ATP2B4/NR2F2/CALR/TMSB4X/ANXA1/LGMN/NF1/EMC10/FOXP1/GATA3/HSPB1/RHOA/ANXA3/CSNK2B 21 GO:0097237 cellular response to toxic substance 14/742 124/18722 0.000402764317333714 0.00839517184653395 MGST3/SOD3/GSTO1/BMP7/GPX3/S100A9/PPP1R9A/GPX8/TXN/PRDX6/GPX1/PRDX4/GPX4/HBA2 14 GO:0008360 regulation of cell shape 16/742 154/18722 0.000414107947661424 0.00854947090459899 DAG1/RHOB/ALDOA/MYH10/ANXA1/PHIP/DLG1/DIAPH1/RASA1/BRWD1/FMNL2/HEXB/MYL12B/RHOBTB3/MYL12A/RHOA 16 GO:0001654 eye development 29/742 371/18722 0.000414293653130952 0.00854947090459899 FBN2/ATP2B1/FBN1/EFEMP1/TENM3/SERPINF1/RPL24/PBX1/FLT1/LRP5/NAGLU/NRP1/BMP7/ATP2B4/CRYBG3/GLI3/NF1/FAT1/DLG1/MAN2A1/NIPBL/TUG1/SMOC1/ATF6/KDM5B/CITED2/GATA3/OBSL1/YY1 29 GO:0008154 actin polymerization or depolymerization 20/742 217/18722 0.00041535891034489 0.00854947090459899 IQGAP2/KANK1/SPTAN1/PFN1/TMSB4X/SPTBN1/DLG1/DIAPH1/WASF2/RASA1/TRIOBP/PPP1R9A/KANK4/CFL1/MSRB2/ARPC3/DSTN/RHOA/CAPZB/COTL1 20 GO:0086065 cell communication involved in cardiac conduction 9/742 58/18722 0.000428883330410707 0.00875489112491277 CAV1/GJA1/DSP/DSG2/DSC2/GJA5/ATP1A1/CALM1/CALM2 9 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 9/742 58/18722 0.000428883330410707 0.00875489112491277 CAV1/RPL26/S100A9/PMAIP1/SERINC3/DDIT3/BCAP31/SIAH1/EIF5A 9 GO:0046697 decidualization 6/742 26/18722 0.000442833230482283 0.00900245332749991 BSG/GJA1/CTSV/ASH1L/JUNB/CITED2 6 GO:0040013 negative regulation of locomotion 30/742 391/18722 0.000452876094823028 0.00916888487059736 FBLN1/LRP1/TCAF1/CDH1/ADGRG1/DAG1/SEMA6A/RHOB/SPINT2/SERPINF1/KANK1/DUSP1/MIF/SEMA6D/GJA1/DPP4/DLG5/NRP1/TACSTD2/ATP2B4/NR2F2/CALR/MIA3/NF1/GNA12/CITED2/GATA3/MARVELD3/RHOA/CSNK2B 30 GO:0003281 ventricular septum development 10/742 71/18722 0.000466468844728276 0.00932937689456552 LRP2/TGFBR3/SOX4/TRIP11/LMO4/GJA5/HECTD1/CITED2/GATA3/HES1 10 GO:0072078 nephron tubule morphogenesis 10/742 71/18722 0.000466468844728276 0.00932937689456552 LAMA5/LGR4/PBX1/TACSTD2/GLI3/MAGED1/DLG1/IRX2/GATA3/HES1 10 GO:0150116 regulation of cell-substrate junction organization 10/742 71/18722 0.000466468844728276 0.00932937689456552 LRP1/MACF1/IQGAP1/NRP1/SLC9A1/ACTG1/PTPRA/ROCK1/S100A10/RHOA 10 GO:0045445 myoblast differentiation 11/742 84/18722 0.000468385767331313 0.00932994230087372 PLEC/ZFP36L1/ISL1/BTG1/DDX17/TCF7L2/IFRD1/DDIT3/DDX5/EPAS1/MBNL3 11 GO:0048762 mesenchymal cell differentiation 21/742 236/18722 0.000482153236358064 0.00956561039200335 NRP2/LAMA5/DAG1/SEMA6A/TGFBR3/SEMA6D/DLG5/RTN4/NRP1/BMP7/ISL1/FOLR1/ROCK1/DDX17/TCF7L2/CITED2/GATA3/DDX5/HES1/PDCD4/SDCBP 21 GO:0006767 water-soluble vitamin metabolic process 9/742 59/18722 0.000488569946329268 0.00965414213946633 SLC2A1/SLC19A1/SLC52A1/GSTO1/FOLR1/SLC19A3/MTR/SLC52A3/SLC52A2 9 GO:0150063 visual system development 29/742 375/18722 0.000493077397803332 0.00970439181334048 FBN2/ATP2B1/FBN1/EFEMP1/TENM3/SERPINF1/RPL24/PBX1/FLT1/LRP5/NAGLU/NRP1/BMP7/ATP2B4/CRYBG3/GLI3/NF1/FAT1/DLG1/MAN2A1/NIPBL/TUG1/SMOC1/ATF6/KDM5B/CITED2/GATA3/OBSL1/YY1 29 GO:0002262 myeloid cell homeostasis 16/742 157/18722 0.000513455355338168 0.0100424057092492 RPS6/UFL1/TGFBR3/PRKDC/ZFP36L1/JAM3/HSPA1A/ANXA1/CDK6/NCSTN/HSPA1B/RPS17/CITED2/GATA3/EPAS1/ADAR 16 GO:0030048 actin filament-based movement 14/742 127/18722 0.000514317539360335 0.0100424057092492 AKAP9/SYNE2/MYH10/CAV1/GJA1/DSP/DSG2/DSC2/GJA5/SLC9A1/DLG1/ACTN4/WASF2/ATP1A1 14 GO:0030433 ubiquitin-dependent ERAD pathway 11/742 85/18722 0.000519116787750235 0.010043641090692 HSP90B1/HSPA5/CAV1/CCDC47/CALR/UBXN4/OS9/CANX/DNAJB14/FAF2/BCAP31 11 GO:0071277 cellular response to calcium ion 11/742 85/18722 0.000519116787750235 0.010043641090692 FOS/HSPA5/JUND/FOSB/FUS/IQGAP1/LGMN/NCSTN/JUNB/SYT7/CACYBP 11 GO:0072006 nephron development 15/742 142/18722 0.000520480186076345 0.010043641090692 LAMA5/ENPEP/IQGAP1/LGR4/PBX1/EGR1/BMP7/TACSTD2/GLI3/MAGED1/DLG1/IRX2/SEC61A1/GATA3/HES1 15 GO:2000146 negative regulation of cell motility 28/742 359/18722 0.000535671867480361 0.0102965720830855 FBLN1/LRP1/TCAF1/CDH1/ADGRG1/DAG1/RHOB/SPINT2/SERPINF1/KANK1/DUSP1/MIF/SEMA6D/GJA1/DPP4/DLG5/TACSTD2/ATP2B4/NR2F2/CALR/MIA3/NF1/GNA12/CITED2/GATA3/MARVELD3/RHOA/CSNK2B 28 GO:0033120 positive regulation of RNA splicing 7/742 37/18722 0.000543603637527664 0.0104085347650646 SLC38A2/SRSF5/HSPA1A/TRA2B/POLR2A/CIRBP/PRDX6 7 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 14/742 128/18722 0.00055690679361359 0.0106220832449851 FBN2/FBN1/PEG10/HSPA5/GLG1/CAV1/TGFBR3/LTBP1/FERMT1/FOLR1/HSPA1A/CITED2/NREP/SDCBP 14 GO:0009755 hormone-mediated signaling pathway 18/742 190/18722 0.000572443486116425 0.0108347541050388 LGR5/UFL1/LGR4/BMP7/ISL1/PRLR/CALR/ESRRA/ARID1A/DDX17/NCOR1/FOXP1/DDX5/PARP1/PTGES3/RHOA/CSNK2B/LBH 18 GO:0030041 actin filament polymerization 18/742 190/18722 0.000572443486116425 0.0108347541050388 IQGAP2/KANK1/SPTAN1/PFN1/TMSB4X/SPTBN1/DLG1/DIAPH1/WASF2/RASA1/TRIOBP/PPP1R9A/KANK4/MSRB2/ARPC3/RHOA/CAPZB/COTL1 18 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 22/742 256/18722 0.000575284511360097 0.0108469675042705 LRP2/FBN2/FBN1/PEG10/HSPA5/LRP1/GLG1/CRIM1/CAV1/TGFBR3/LTBP1/BMP7/FERMT1/FOLR1/HSPA1A/FSTL1/CITED2/PARP1/HES1/NREP/CSNK2B/SDCBP 22 GO:0072088 nephron epithelium morphogenesis 10/742 73/18722 0.00058467373002055 0.0109404857056876 LAMA5/LGR4/PBX1/TACSTD2/GLI3/MAGED1/DLG1/IRX2/GATA3/HES1 10 GO:0086003 cardiac muscle cell contraction 10/742 73/18722 0.00058467373002055 0.0109404857056876 AKAP9/CAV1/GJA1/DSP/DSG2/DSC2/GJA5/SLC9A1/DLG1/ATP1A1 10 GO:0035966 response to topologically incorrect protein 16/742 159/18722 0.000590488550412193 0.0110075978831556 HSPA5/UFL1/SERPINH1/PPP1R15A/HSPA1A/UBXN4/OS9/HSPA1B/DNAJB14/FAF2/CREB3L2/ATF6/MBTPS1/DDIT3/HSPB1/DNAJB1 16 GO:0060964 regulation of gene silencing by miRNA 8/742 49/18722 0.000626001985384418 0.0116257511571392 EGFR/NEAT1/KCNQ1OT1/EIF4G1/TNRC6B/PUM1/NCOR1/DDX5 8 GO:0030865 cortical cytoskeleton organization 9/742 61/18722 0.000628443798599409 0.0116273871351351 RHOB/PLEC/CALR/DLG1/ROCK1/FMNL2/RHOBTB3/TLN1/RHOA 9 GO:0030099 myeloid cell differentiation 29/742 381/18722 0.000636012245929624 0.0117235093092998 JUN/FBN1/FOS/CSF3R/APP/RPS6/UFL1/TFRC/TGFBR3/PRKDC/ZFP36L1/ATP6AP1/ESRRA/HSPA1A/CD81/CDK6/JUNB/WASF2/HSPA1B/TET2/FOXP1/NFKBIA/CITED2/GATA3/EPAS1/ADAR/PARP1/CDC42/DHRS2 29 GO:0001731 formation of translation preinitiation complex 4/742 11/18722 0.000646105215326051 0.0117777113052055 RPL13A/EIF2S2/EIF4H/EIF4B 4 GO:0035581 sequestering of extracellular ligand from receptor 4/742 11/18722 0.000646105215326051 0.0117777113052055 FBN2/FBN1/CD46/LTBP1 4 GO:0075522 IRES-dependent viral translational initiation 4/742 11/18722 0.000646105215326051 0.0117777113052055 EIF3A/PCBP2/EIF3F/SSB 4 GO:0048844 artery morphogenesis 10/742 74/18722 0.000652466761948188 0.0118499478089119 LRP2/LRP1/SOX4/NRP1/GJA5/FOLR1/NF1/CITED2/HES1/HPGD 10 GO:0050769 positive regulation of neurogenesis 20/742 225/18722 0.000659388367774359 0.0119317895121074 LRP2/EGFR/SPINT1/LRP1/DAG1/GOLGA4/SERPINF1/MACF1/UFL1/IL6ST/NRP1/MME/CUX1/GLI3/MAN2A1/DHX36/OBSL1/HES1/TGM2/RAB11A 20 GO:0050767 regulation of neurogenesis 28/742 364/18722 0.000664995863435202 0.0119893414794522 LRP2/EGFR/SPINT1/LRP1/DAG1/GOLGA4/SEMA6A/SERPINF1/MACF1/UFL1/IL6ST/SEMA6D/RTN4/NRP1/BMP7/MME/CUX1/GLI3/NF1/MAN2A1/DHX36/PCM1/OBSL1/ID1/HES1/TGM2/RAB11A/DYNLT1 28 GO:1990748 cellular detoxification 13/742 116/18722 0.000688315491608201 0.0123646491947073 MGST3/SOD3/GSTO1/BMP7/GPX3/S100A9/GPX8/TXN/PRDX6/GPX1/PRDX4/GPX4/HBA2 13 GO:0007043 cell-cell junction assembly 15/742 146/18722 0.000697567469608781 0.0124333097053108 CLDN4/CAV1/GJA1/PKN2/LSR/DLG5/JAM3/GJA5/ACTG1/CTNND1/DLG1/ROCK1/MARVELD3/TLN1/RHOA 15 GO:0001843 neural tube closure 11/742 88/18722 0.000699607633730021 0.0124333097053108 LRP2/SPINT1/SPINT2/LMO4/FOLR1/PFN1/BRD2/ST14/HECTD1/ADM/CITED2 11 GO:0019079 viral genome replication 14/742 131/18722 0.000703082611287009 0.0124333097053108 HACD3/PKN2/EEA1/MPHOSPH8/DDB1/STOM/PPIA/EIF2AK4/LARP1/PCBP2/DDX5/ADAR/CDC42/BANF1 14 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 14/742 131/18722 0.000703082611287009 0.0124333097053108 FBN2/FBN1/PEG10/HSPA5/GLG1/CAV1/TGFBR3/LTBP1/FERMT1/FOLR1/HSPA1A/CITED2/NREP/SDCBP 14 GO:0007039 protein catabolic process in the vacuole 5/742 19/18722 0.000705586202677024 0.0124333097053108 LRP2/LRP1/CD81/LAMP2/CLN3 5 GO:0060675 ureteric bud morphogenesis 9/742 62/18722 0.000709755736214096 0.0124333097053108 LAMA5/LGR4/PBX1/TACSTD2/GLI3/MAGED1/DLG1/GATA3/HES1 9 GO:1903078 positive regulation of protein localization to plasma membrane 9/742 62/18722 0.000709755736214096 0.0124333097053108 EGFR/LRP1/ITGB1/ATP2B4/SPTBN1/KIF5B/DLG1/CLN3/RAB11A 9 GO:0009266 response to temperature stimulus 17/742 178/18722 0.000734942377429261 0.0128290294858677 ATP2B1/FOS/TPR/HSPA1A/SLC9A1/ADRB1/HSPA1B/SLC52A3/ACADVL/ADM/DHX36/EIF2AK4/CIRBP/NFKBIA/NR2F6/DNAJB1/YWHAE 17 GO:0060537 muscle tissue development 30/742 403/18722 0.0007421556776977 0.0129093276331924 LRP2/FOS/ITGB1/PLEC/CAV1/TGFBR3/GJA1/DSP/DSG2/EGR1/BMP7/ISL1/NR2F2/CALR/GJA5/SLC9A1/GPC1/NF1/DLG1/AKAP13/DDX17/CITED2/DDX5/OBSL1/GPX1/YY1/CDC42/RHOA/IGF2/CACYBP 30 GO:0086091 regulation of heart rate by cardiac conduction 7/742 39/18722 0.000758204347785697 0.0130475728409046 AKAP9/CAV1/DSP/DSG2/DSC2/ISL1/YWHAE 7 GO:0045667 regulation of osteoblast differentiation 14/742 132/18722 0.00075850726212128 0.0130475728409046 FBN2/JUND/CRIM1/IL6ST/ATP6AP1/LRP5/BMP7/SUCO/ESRRA/CDK6/GLI3/SMOC1/DDX5/ATRAID 14 GO:0072594 establishment of protein localization to organelle 31/742 422/18722 0.000759838772007779 0.0130475728409046 HSPA5/CDH1/LMAN1/SEC62/RPL23/PPP1R10/GCC2/TPR/FERMT1/VPS13C/GLI3/RANBP2/NIPBL/NMT1/LAMP2/SEC61A1/GNPTAB/LAMP1/SEC63/DDIT3/NFKBIA/CALM1/HUWE1/SPCS2/KPNB1/RAN/BCAP31/LEPROT/RAB11A/UBE2L3/CCT3 31 GO:0048193 Golgi vesicle transport 24/742 296/18722 0.000760668214206587 0.0130475728409046 GOLGA4/LMAN1/MACF1/TMED9/TRIP11/PLPP3/ANK3/GCC2/MIA3/CUX1/SPTBN1/VPS13C/TMED4/PGAP1/CREB3L2/LMAN2/VAMP2/SCAMP2/LAMP1/ERGIC2/TMED1/KRT18/CLN3/BCAP31 24 GO:0060606 tube closure 11/742 89/18722 0.000770274739900577 0.0131637503898583 LRP2/SPINT1/SPINT2/LMO4/FOLR1/PFN1/BRD2/ST14/HECTD1/ADM/CITED2 11 GO:0002027 regulation of heart rate 12/742 103/18722 0.000772770771874273 0.0131637503898583 AKAP9/CAV1/DSP/DSG2/DSC2/ISL1/ADRB1/ADM/CALM1/EPAS1/CALM2/YWHAE 12 GO:0030705 cytoskeleton-dependent intracellular transport 18/742 195/18722 0.000777425872068674 0.0131975388591727 ARMCX3/APP/SYNE2/DYNC1H1/DST/HOOK2/ARHGAP21/KIF5B/ACTN4/PURA/IFT27/LAMP1/PCM1/HSPB1/CLN3/CDC42/TUBA1C/TUBA1B 18 GO:0072171 mesonephric tubule morphogenesis 9/742 63/18722 0.000799446602543682 0.0135248843033075 LAMA5/LGR4/PBX1/TACSTD2/GLI3/MAGED1/DLG1/GATA3/HES1 9 GO:0031100 animal organ regeneration 10/742 76/18722 0.000807570769461297 0.0136156982974021 EGFR/RPS16/RPL19/TGFBR3/SRSF5/GLI3/UPF2/ADM/ANXA3/CSNK2B 10 GO:0051402 neuron apoptotic process 21/742 246/18722 0.000827901883165525 0.0139110044314207 JUN/GAPDH/HSPA5/LRP1/GRN/APP/NRP1/ISL1/LGMN/NF1/NCSTN/RASA1/ERBB3/DDIT3/GATA3/GPX1/PARP1/CLN3/SIAH1/CDC42/RHOA 21 GO:0051960 regulation of nervous system development 32/742 443/18722 0.0008341524231859 0.0139685185441978 LRP2/EGFR/SPINT1/LRP1/DAG1/GOLGA4/SEMA6A/CTSC/SERPINF1/MACF1/UFL1/IL6ST/SEMA6D/DLG5/RTN4/NRP1/BMP7/MME/CUX1/GLI3/NF1/DLG1/MAN2A1/TPBG/DHX36/PCM1/OBSL1/ID1/HES1/TGM2/RAB11A/DYNLT1 32 GO:1903076 regulation of protein localization to plasma membrane 12/742 104/18722 0.000842765695729132 0.0140369559810913 EGFR/LRP1/ITGB1/ATP2B4/TMEM59/SPTBN1/KIF5B/DLG1/HECTD1/CLTC/CLN3/RAB11A 12 GO:0002028 regulation of sodium ion transport 11/742 90/18722 0.000846763741369475 0.0140369559810913 UTRN/ANK3/ATP2B4/PRSS8/SLC9A1/KIF5B/DLG1/STOM/ACTN4/ATP1A1/FXYD3 11 GO:0034109 homotypic cell-cell adhesion 11/742 90/18722 0.000846763741369475 0.0140369559810913 IL6ST/DSP/DSG2/PLPP3/DSC2/ANK3/ACTG1/PPIA/HSPB1/TLN1/MYL12A 11 GO:0031098 stress-activated protein kinase signaling cascade 21/742 247/18722 0.000872054524059674 0.0144078573540294 EGFR/APP/GADD45B/DUSP1/HACD3/ZFP36L1/IGF1R/ARL6IP5/DLG1/EMC10/DUSP9/NCOR1/PPIA/RB1CC1/RNF13/MARVELD3/GADD45G/CDC42/RHOA/PDCD4/SDCBP 21 GO:0043001 Golgi to plasma membrane protein transport 7/742 40/18722 0.000888036458832578 0.0146230003554431 GOLGA4/MACF1/ANK3/SPTBN1/VAMP2/KRT18/CLN3 7 GO:0007492 endoderm development 10/742 77/18722 0.000895794021582 0.0146530545252155 ITGAV/LAMB1/LAMC1/COL4A2/DUSP1/BPTF/ZFP36L1/MMP15/ITGB5/RTF1 10 GO:0021675 nerve development 10/742 77/18722 0.000895794021582 0.0146530545252155 NRP2/DAG1/RPL24/CTSV/NRP1/ISL1/GLI3/ERBB3/CITED2/HES1 10 GO:0048568 embryonic organ development 31/742 427/18722 0.000920753376632873 0.0150116227081399 FBN2/FBN1/SPINT1/KRT19/EFEMP1/SPINT2/BPTF/PBX1/ZFP36L1/KRT8/NAGLU/BMP7/NR2F2/FOLR1/GLI3/JUNB/DLG1/RBBP6/TRA2B/NIPBL/TRIOBP/ST14/HECTD1/SLC39A1/ADM/ATP6V1B1/CITED2/GATA3/EPAS1/HES1/IGF2 31 GO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane 4/742 12/18722 0.000938875992527265 0.0150452642933353 HSPA5/SEC62/SEC61A1/SEC63 4 GO:0061307 cardiac neural crest cell differentiation involved in heart development 4/742 12/18722 0.000938875992527265 0.0150452642933353 BMP7/FOLR1/CITED2/HES1 4 GO:0061308 cardiac neural crest cell development involved in heart development 4/742 12/18722 0.000938875992527265 0.0150452642933353 BMP7/FOLR1/CITED2/HES1 4 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress 4/742 12/18722 0.000938875992527265 0.0150452642933353 JUN/HSPA1A/CITED2/DNAJB1 4 GO:1990034 calcium ion export across plasma membrane 4/742 12/18722 0.000938875992527265 0.0150452642933353 ATP2B1/CALM1/CALM2/YWHAE 4 GO:0021545 cranial nerve development 8/742 52/18722 0.000941090418348299 0.0150452642933353 NRP2/RPL24/NRP1/ISL1/GLI3/ERBB3/CITED2/HES1 8 GO:0051897 positive regulation of protein kinase B signaling 13/742 120/18722 0.000948430672137291 0.0151137016785749 LRP2/EGFR/ITGB1/MET/RTN4/IGF1R/MYDGF/TPBG/TCF7L2/TXN/GATA3/GPX1/IGF2 13 GO:0045070 positive regulation of viral genome replication 6/742 30/18722 0.000997905284486024 0.0158124639260162 HACD3/PKN2/DDB1/PPIA/LARP1/ADAR 6 GO:0006766 vitamin metabolic process 12/742 106/18722 0.000998681932169444 0.0158124639260162 LRP2/SLC2A1/SLC19A1/SLC52A1/GSTO1/FOLR1/LGMN/SLC19A3/MTR/SLC52A3/SLC52A2/CYP11A1 12 GO:0048524 positive regulation of viral process 9/742 65/18722 0.00100651701584124 0.0158733386923226 P4HB/HACD3/PKN2/DDB1/STOM/PPIA/RSF1/LARP1/ADAR 9 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 25/742 320/18722 0.0010161227989685 0.0158733386923226 SON/SF1/RBM39/SRRM2/SCAF11/NPM1/PNN/RBM25/SRSF5/LUC7L3/TRA2B/HNRNPA1/DDX17/SRSF7/DDX46/SRSF6/CELF1/CIRBP/SF3B1/PRDX6/DDX5/SNRPD2/HNRNPC/MBNL3/SNRPC 25 GO:0000398 mRNA splicing, via spliceosome 25/742 320/18722 0.0010161227989685 0.0158733386923226 SON/SF1/RBM39/SRRM2/SCAF11/NPM1/PNN/RBM25/SRSF5/LUC7L3/TRA2B/HNRNPA1/DDX17/SRSF7/DDX46/SRSF6/CELF1/CIRBP/SF3B1/PRDX6/DDX5/SNRPD2/HNRNPC/MBNL3/SNRPC 25 GO:0003158 endothelium development 14/742 136/18722 0.00101859278653163 0.0158733386923226 RHOB/MET/GJA1/NRP1/NR2F2/GJA5/FSTL1/BTG1/ROCK1/FOXP1/GPX1/ID1/RHOA/CSNK2B 14 GO:0043401 steroid hormone mediated signaling pathway 14/742 136/18722 0.00101859278653163 0.0158733386923226 UFL1/BMP7/ISL1/CALR/ESRRA/ARID1A/DDX17/NCOR1/FOXP1/DDX5/PARP1/PTGES3/RHOA/LBH 14 GO:0006417 regulation of translation 33/742 468/18722 0.00104781415645089 0.0162773645687654 GAPDH/RPL13A/APP/SOX4/RPL26/PRKDC/ZFP36L1/PPP1R15A/NPM1/TPR/TNRC6A/CALR/EIF4G1/TNRC6B/YBX1/ROCK1/PUM1/NEMF/PURA/EIF3H/DHX36/EIF2AK4/CELF1/LARP1/CIRBP/PKM/HSPB1/EIF1/IGF2BP3/RHOA/EIF4H/EIF5A/EIF4B 33 GO:0050708 regulation of protein secretion 22/742 268/18722 0.00105559710832754 0.0163468643107776 EGFR/LRP1/KCNN4/WLS/ERP29/MYH10/SOX4/GJA1/DPP4/DYNLL1/LRP5/ISL1/FRMD4A/ANXA1/KIF5B/P3H1/TCF7L2/SYT7/PPIA/SLC16A1/HMGN3/PHPT1 22 GO:0050714 positive regulation of protein secretion 14/742 137/18722 0.00109420143005401 0.0168145431729654 EGFR/LRP1/KCNN4/WLS/MYH10/SOX4/GJA1/DYNLL1/ISL1/FRMD4A/KIF5B/TCF7L2/PPIA/PHPT1 14 GO:0060048 cardiac muscle contraction 14/742 137/18722 0.00109420143005401 0.0168145431729654 AKAP9/GAA/CAV1/GJA1/DSP/DSG2/DSC2/GSTO1/GJA5/SLC9A1/DLG1/ATP1A1/CALM1/CALM2 14 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 10/742 79/18722 0.00109600868455362 0.0168145431729654 P4HB/PRKDC/NRP1/CALR/CUX1/TRIOBP/DHX36/OBSL1/S100A10/CDC42 10 GO:0090257 regulation of muscle system process 21/742 252/18722 0.00112457046260998 0.0171993129575644 AKAP9/ATP2B1/DAG1/CAV1/IL6ST/DSP/DSG2/DSC2/GSTO1/ATP2B4/GJA5/SLC9A1/ENO1/DLG1/ROCK1/ATP1A1/CALM1/PARP1/YY1/RHOA/CALM2 21 GO:0021543 pallium development 16/742 169/18722 0.00114115142935657 0.0173990372253749 LRP1/ADGRG1/SLC2A1/LAMB1/SLC38A2/RTN4/TACC2/ATP2B4/CDK6/GLI3/KIF5B/NF1/TRA2B/CELF1/RHOA/ANXA3 16 GO:1901653 cellular response to peptide 27/742 359/18722 0.00115035315556177 0.0174663657081467 ATP2B1/FBN1/LRP1/APP/KANK1/CAV1/GJA1/RPL23/PRKDC/ZFP36L1/CSH1/IGF1R/POR/SRSF5/ESRRA/SLC9A1/PHIP/LGMN/PTPRA/ROCK1/VAMP2/PKM/ID1/PARP1/LEPROT/CYP11A1/IGF2 27 GO:0048485 sympathetic nervous system development 5/742 21/18722 0.00115617441023562 0.0174663657081467 NRP2/SOX4/NRP1/NF1/GATA3 5 GO:0060445 branching involved in salivary gland morphogenesis 5/742 21/18722 0.00115617441023562 0.0174663657081467 LAMA5/DAG1/NRP1/BMP7/TGM2 5 GO:0006091 generation of precursor metabolites and energy 34/742 490/18722 0.00116498531652375 0.0175458154378881 GAPDH/APP/LDHA/GAA/COX6A1/ALDOA/GLDC/PLEC/ACSS1/IL6ST/AGL/POR/IL10RB/TPI1/DEGS1/CROT/ENO1/ASPH/NCOR1/ACADVL/RB1CC1/NDUFB9/PKM/UQCRH/PTGES3/DHRS2/COX8C/RHOA/IGF2/PYGL/UGP2/CYP19A1/COX5A/ETFA 34 GO:0071711 basement membrane organization 6/742 31/18722 0.00119643287650688 0.0179102376058909 LAMB1/ITGB1/DAG1/SPINT2/CAV1/FERMT1 6 GO:0090162 establishment of epithelial cell polarity 6/742 31/18722 0.00119643287650688 0.0179102376058909 FERMT1/FRMD4A/FAT1/HES1/CDC42/RHOA 6 GO:0051168 nuclear export 15/742 154/18722 0.00120831980263429 0.0179670808392764 NPM1/TPR/CALR/PABPN1/UPF2/AKAP13/HNRNPA1/NEMF/TCF7L2/THOC2/PTPN14/TXN/RAN/YWHAE/SSB 15 GO:0000375 RNA splicing, via transesterification reactions 25/742 324/18722 0.00120973570577589 0.0179670808392764 SON/SF1/RBM39/SRRM2/SCAF11/NPM1/PNN/RBM25/SRSF5/LUC7L3/TRA2B/HNRNPA1/DDX17/SRSF7/DDX46/SRSF6/CELF1/CIRBP/SF3B1/PRDX6/DDX5/SNRPD2/HNRNPC/MBNL3/SNRPC 25 GO:0086002 cardiac muscle cell action potential involved in contraction 8/742 54/18722 0.0012138386713083 0.0179670808392764 CAV1/GJA1/DSP/DSG2/DSC2/GJA5/DLG1/ATP1A1 8 GO:0019080 viral gene expression 11/742 94/18722 0.00121841540104405 0.0179670808392764 JUN/EIF3A/CANX/MAN2A1/MOGS/FUT8/RSF1/EIF2AK4/PCBP2/EIF3F/SSB 11 GO:0061326 renal tubule development 11/742 94/18722 0.00121841540104405 0.0179670808392764 LAMA5/LGR5/LGR4/PBX1/TACSTD2/GLI3/MAGED1/DLG1/IRX2/GATA3/HES1 11 GO:0030900 forebrain development 28/742 379/18722 0.00123075741658297 0.0180950643985711 LRP2/NRP2/LRP1/CDH1/ADGRG1/APP/SLC2A1/LAMB1/ATRX/SLC38A2/RTN4/NRP1/TACC2/ATP2B4/ISL1/NR2F2/CDK6/GLI3/KIF5B/NF1/TRA2B/PGAP1/CELF1/PCM1/DNAJB1/HES1/RHOA/ANXA3 28 GO:0061077 chaperone-mediated protein folding 9/742 67/18722 0.00125503276358625 0.018397216178386 HSPA5/PDIA4/HSPA1A/P3H1/HSPA1B/DNAJB14/HSPB1/DNAJB1/PTGES3 9 GO:0008064 regulation of actin polymerization or depolymerization 17/742 187/18722 0.00127208159460829 0.018591961767352 IQGAP2/KANK1/SPTAN1/PFN1/TMSB4X/SPTBN1/DLG1/WASF2/RASA1/TRIOBP/PPP1R9A/KANK4/ARPC3/DSTN/RHOA/CAPZB/COTL1 17 GO:0051962 positive regulation of nervous system development 22/742 272/18722 0.00127854135236488 0.0186312515654352 LRP2/EGFR/SPINT1/LRP1/DAG1/GOLGA4/SERPINF1/MACF1/UFL1/IL6ST/DLG5/NRP1/MME/CUX1/GLI3/MAN2A1/TPBG/DHX36/OBSL1/HES1/TGM2/RAB11A 22 GO:0030833 regulation of actin filament polymerization 16/742 171/18722 0.00129208987016663 0.0187733057606563 IQGAP2/KANK1/SPTAN1/PFN1/TMSB4X/SPTBN1/DLG1/WASF2/RASA1/TRIOBP/PPP1R9A/KANK4/ARPC3/RHOA/CAPZB/COTL1 16 GO:0032352 positive regulation of hormone metabolic process 4/742 13/18722 0.00131383957049699 0.0189776826849565 EGR1/POR/ADM/GATA3 4 GO:0060670 branching involved in labyrinthine layer morphogenesis 4/742 13/18722 0.00131383957049699 0.0189776826849565 SPINT1/SPINT2/ST14/ADM 4 GO:0014032 neural crest cell development 10/742 81/18722 0.00133137426376545 0.0191748946443188 NRP2/LAMA5/SEMA6A/SEMA6D/NRP1/BMP7/ISL1/FOLR1/CITED2/HES1 10 GO:0030832 regulation of actin filament length 17/742 188/18722 0.00134838254682877 0.0193634005271341 IQGAP2/KANK1/SPTAN1/PFN1/TMSB4X/SPTBN1/DLG1/WASF2/RASA1/TRIOBP/PPP1R9A/KANK4/ARPC3/DSTN/RHOA/CAPZB/COTL1 17 GO:0001755 neural crest cell migration 8/742 55/18722 0.00137199878155989 0.0195558868137338 NRP2/LAMA5/SEMA6A/SEMA6D/NRP1/BMP7/ISL1/FOLR1 8 GO:0048736 appendage development 16/742 172/18722 0.00137366249481086 0.0195558868137338 FBN2/ITGB4/ITGA6/ATRX/SOX4/PBX1/LRP5/FRAS1/BMP7/NR2F2/GLI3/ZNRF3/NIPBL/SMOC1/SLC39A1/TMEM107 16 GO:0060173 limb development 16/742 172/18722 0.00137366249481086 0.0195558868137338 FBN2/ITGB4/ITGA6/ATRX/SOX4/PBX1/LRP5/FRAS1/BMP7/NR2F2/GLI3/ZNRF3/NIPBL/SMOC1/SLC39A1/TMEM107 16 GO:1904375 regulation of protein localization to cell periphery 13/742 125/18722 0.00138474854288947 0.0196037795876778 EGFR/LRP1/ITGB1/DAG1/ATP2B4/TMEM59/SPTBN1/KIF5B/DLG1/HECTD1/CLTC/CLN3/RAB11A 13 GO:0014002 astrocyte development 7/742 43/18722 0.00138496337572865 0.0196037795876778 EGFR/LRP1/GRN/APP/CDK6/NF1/S100A9 7 GO:0060411 cardiac septum morphogenesis 9/742 68/18722 0.00139663198907313 0.0196563020684367 LRP2/NRP2/TGFBR3/SOX4/NRP1/BMP7/ISL1/CITED2/HES1 9 GO:1902305 regulation of sodium ion transmembrane transport 9/742 68/18722 0.00139663198907313 0.0196563020684367 UTRN/ANK3/ATP2B4/SLC9A1/KIF5B/DLG1/STOM/ACTN4/FXYD3 9 GO:0007435 salivary gland morphogenesis 6/742 32/18722 0.00142381802352697 0.0199253853717373 LAMA5/DAG1/NRP1/BMP7/CDC42/TGM2 6 GO:0072337 modified amino acid transport 6/742 32/18722 0.00142381802352697 0.0199253853717373 LRP2/SLC38A2/GJA1/SLC19A1/FOLR1/SLC16A12 6 GO:0032355 response to estradiol 14/742 141/18722 0.00144543216611878 0.0201481882102537 EGFR/DUSP1/GJA1/SLC6A4/MMP15/BMP7/NR2F2/CALR/ESRRA/ANXA1/NCOA3/GPX4/HPGD/CYP19A1 14 GO:0099563 modification of synaptic structure 5/742 22/18722 0.0014478961163239 0.0201481882102537 MYH10/PFN1/CLN3/CDC42/RHOA 5 GO:0051099 positive regulation of binding 16/742 173/18722 0.00145953111616657 0.0202530441400642 LRP1/APP/MET/CAV1/NRP1/ISL1/EIF4G1/TCF7L2/TXN/CALM1/GATA3/PARP1/RAN/S100A10/HES1/CALM2 16 GO:0051017 actin filament bundle assembly 15/742 157/18722 0.00146760426722221 0.0203080254343914 HSP90B1/MET/NRP1/TACSTD2/PFN1/SLC9A1/ITGB5/ACTG1/WASF2/ROCK1/PPP1R9A/ID1/S100A10/CDC42/RHOA 15 GO:0010639 negative regulation of organelle organization 26/742 347/18722 0.00148401784672572 0.0204777881643158 MET/KANK1/TFRC/DUSP1/ATRX/SPTAN1/NPM1/BMP7/TACSTD2/TPR/PFN1/TMSB4X/SPTBN1/HSPA1A/WASF2/TRIOBP/PPP1R9A/HNRNPA1/KANK4/RAD50/HUWE1/GPX1/PARP1/HNRNPC/CAPZB/LCMT1 26 GO:2001235 positive regulation of apoptotic signaling pathway 13/742 126/18722 0.00148946393603877 0.0204956875878315 CTSC/PDIA3/CAV1/RPL26/S100A9/PMAIP1/MAGED1/TIMP3/SERINC3/DDIT3/BCAP31/SIAH1/EIF5A 13 GO:0014706 striated muscle tissue development 28/742 384/18722 0.00149524727591281 0.020518115397248 LRP2/FOS/ITGB1/PLEC/CAV1/TGFBR3/GJA1/DSP/DSG2/EGR1/BMP7/ISL1/NR2F2/CALR/GJA5/SLC9A1/GPC1/AKAP13/DDX17/CITED2/DDX5/OBSL1/GPX1/YY1/CDC42/RHOA/IGF2/CACYBP 28 GO:0010332 response to gamma radiation 8/742 56/18722 0.0015460980042778 0.0210466414708258 HSPA5/RPL26/EGR1/PRKDC/TMEM109/GATA3/GPX1/PARP1 8 GO:0015807 L-amino acid transport 9/742 69/18722 0.00155080516100822 0.0210466414708258 ITGB1/SLC3A2/SLC38A1/SLC43A2/SLC38A2/SLC1A5/ARL6IP5/SLC38A9/SERINC3 9 GO:0045669 positive regulation of osteoblast differentiation 9/742 69/18722 0.00155080516100822 0.0210466414708258 FBN2/JUND/IL6ST/ATP6AP1/LRP5/BMP7/SUCO/GLI3/ATRAID 9 GO:1904377 positive regulation of protein localization to cell periphery 9/742 69/18722 0.00155080516100822 0.0210466414708258 EGFR/LRP1/ITGB1/ATP2B4/SPTBN1/KIF5B/DLG1/CLN3/RAB11A 9 GO:0051604 protein maturation 23/742 294/18722 0.00155893958499184 0.0210990727393417 CTSL/GLG1/ENPEP/SOX4/DHCR24/SERPINH1/TMEM59/CALR/MME/GLI3/ENO1/ASPH/LGMN/ATP6AP2/NCSTN/PISD/CPD/SPCS2/YME1L1/PARP1/CLN3/HM13/PRDX4 23 GO:0021762 substantia nigra development 7/742 44/18722 0.00159157787438877 0.0214819527308211 HSPA5/DYNLL1/CALM1/CDC42/RHOA/CALM2/YWHAE 7 GO:1903320 regulation of protein modification by small protein conjugation or removal 20/742 242/18722 0.00161193182028402 0.0216973928942863 HSPA5/RPS20/MYCBP2/UFL1/CAV1/SOX4/RPL23/EGR1/RPS2/NPM1/HSPA1A/TRIM44/HSPA1B/PPIA/HUWE1/EPAS1/SKP1/SIAH2/UBE2L3/UBE2C 20 GO:0010001 glial cell differentiation 19/742 225/18722 0.00162762534875033 0.0217898894927552 EGFR/SPINT1/ITGB4/LRP1/GRN/APP/DAG1/PLEC/SOX4/IL6ST/CDK6/GLI3/GPC1/NF1/NCSTN/S100A9/ERBB3/HES1/RHOA 19 GO:0016485 protein processing 19/742 225/18722 0.00162762534875033 0.0217898894927552 CTSL/GLG1/ENPEP/DHCR24/TMEM59/MME/GLI3/ENO1/ASPH/LGMN/ATP6AP2/NCSTN/PISD/CPD/SPCS2/YME1L1/PARP1/CLN3/HM13 19 GO:0044772 mitotic cell cycle phase transition 30/742 424/18722 0.00164726876691206 0.0219932640771502 EGFR/APP/ITGB1/RPS6/RPL24/DUSP1/SOX4/RPL26/ADAMTS1/PBX1/PRKDC/ZFP36L1/TPR/BRD4/ANXA1/CDK6/DDB1/EIF4G1/DLG1/CTDSPL/BRD7/CALM1/NEK6/RAB11A/ANAPC11/CALM2/UBE2C/PSME2/LCMT1/CCNE1 30 GO:0030010 establishment of cell polarity 14/742 143/18722 0.00165359713264779 0.0220182475344477 ITGB1/KANK1/GJA1/JAM3/FERMT1/FRMD4A/FAT1/ROCK1/GATA3/DOCK8/HES1/CDC42/RHOA/DYNLT1 14 GO:0022898 regulation of transmembrane transporter activity 22/742 278/18722 0.00168819992891054 0.0224185689484357 AKAP9/AHNAK/TCAF1/APP/ITGB1/UTRN/CAV1/GJA1/ANK3/C4orf3/GSTO1/TMSB4X/SLC9A1/KIF5B/DLG1/STOM/ACTN4/VAMP2/CALM1/FXYD3/CALM2/YWHAE 22 GO:0006486 protein glycosylation 19/742 226/18722 0.00171302356527728 0.0225869375806329 RPN2/EXTL2/GALNT11/TRIP11/DDOST/TMEM59/B4GAT1/MAN2A1/B3GAT3/C1GALT1/MAN1A2/MOGS/TUSC3/C1GALT1C1/GXYLT1/TET2/TMEM165/FUT8/RPN1 19 GO:0043413 macromolecule glycosylation 19/742 226/18722 0.00171302356527728 0.0225869375806329 RPN2/EXTL2/GALNT11/TRIP11/DDOST/TMEM59/B4GAT1/MAN2A1/B3GAT3/C1GALT1/MAN1A2/MOGS/TUSC3/C1GALT1C1/GXYLT1/TET2/TMEM165/FUT8/RPN1 19 GO:1902905 positive regulation of supramolecular fiber organization 18/742 209/18722 0.00171459546411687 0.0225869375806329 AKAP9/APP/IQGAP2/MET/CLIP1/NRP1/PFN1/HSPA1A/DLG1/WASF2/HSPA1B/GPX1/ID1/S100A10/CDC42/ARPC3/DSTN/RHOA 18 GO:0045861 negative regulation of proteolysis 26/742 351/18722 0.00174295068558924 0.0228994052840714 ITIH5/GAPDH/APLP2/SPINT1/LRP1/APP/GLG1/CRIM1/SPINT2/SERPINF1/DHCR24/RPL23/SERPINH1/POR/TMEM59/ROCK1/CST3/TIMP3/EIF3H/GPX1/TFPI2/SIAH2/CLN3/SERPINB9/SERPINB1/SDCBP 26 GO:0010975 regulation of neuron projection development 31/742 445/18722 0.00177248583988515 0.0231060271836873 HSPA5/LRP1/GRN/ITGA6/GOLGA4/SEMA6A/TENM3/SERPINF1/MACF1/KANK1/IQGAP1/SEMA6D/RTN4/NRP1/BMP7/PTPRF/CUX1/S100A9/KIDINS220/P3H1/PPP1R9A/CREB3L2/CFL1/THOC2/DHX36/GATA3/OBSL1/ID1/RHOA/RAB11A/DYNLT1 31 GO:0010771 negative regulation of cell morphogenesis involved in differentiation 4/742 14/18722 0.00178206403987548 0.0231060271836873 FBLN1/KANK1/TACSTD2/ACTN4 4 GO:0035437 maintenance of protein localization in endoplasmic reticulum 4/742 14/18722 0.00178206403987548 0.0231060271836873 HSPA5/GJA1/OS9/GPAA1 4 GO:0061709 reticulophagy 4/742 14/18722 0.00178206403987548 0.0231060271836873 UFL1/RB1CC1/TEX264/UFC1 4 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading 4/742 14/18722 0.00178206403987548 0.0231060271836873 FBLN1/KANK1/TACSTD2/ACTN4 4 GO:0018279 protein N-linked glycosylation via asparagine 5/742 23/18722 0.00179039265269407 0.0231532452992374 RPN2/DDOST/TUSC3/FUT8/RPN1 5 GO:0098657 import into cell 19/742 227/18722 0.00180218495503914 0.0232448921093821 LRP2/SLC39A10/SLC2A1/ITGB1/SLC12A9/SLC3A2/SLC38A1/SLC43A2/SLC1A5/SLC27A2/SLC19A1/SLC6A4/ATP2B4/ARL6IP5/FOLR1/SLC9A1/DLG1/SLC5A3/ATP1A1 19 GO:0031396 regulation of protein ubiquitination 18/742 210/18722 0.00180796819543594 0.023258757514202 HSPA5/RPS20/MYCBP2/UFL1/CAV1/SOX4/RPL23/RPS2/NPM1/HSPA1A/TRIM44/HSPA1B/PPIA/HUWE1/SKP1/SIAH2/UBE2L3/UBE2C 18 GO:0009636 response to toxic substance 21/742 262/18722 0.00182176536012058 0.0233753789064823 FOS/CDH1/MGST3/UBA52/SOD3/SLC6A4/GSTO1/BMP7/GPX3/S100A9/PPP1R9A/PON2/GPX8/KDM5B/TXN/PRDX6/GPX1/PRDX4/DHRS2/GPX4/HBA2 21 GO:0034101 erythrocyte homeostasis 13/742 129/18722 0.00184374630124104 0.0235961314200278 RPS6/UFL1/TGFBR3/PRKDC/ZFP36L1/HSPA1A/CDK6/HSPA1B/RPS17/CITED2/GATA3/EPAS1/ADAR 13 GO:0098739 import across plasma membrane 16/742 177/18722 0.00184955963397446 0.0236093658703717 LRP2/SLC39A10/SLC2A1/ITGB1/SLC12A9/SLC3A2/SLC43A2/SLC1A5/SLC19A1/ATP2B4/ARL6IP5/FOLR1/SLC9A1/DLG1/SLC5A3/ATP1A1 16 GO:0006814 sodium ion transport 20/742 245/18722 0.00186591005634194 0.023756689892601 UTRN/SLC3A2/SLC38A1/SLC38A2/MAGED2/SLC6A4/ANK3/SLC13A4/ATP2B4/SLC38A10/PRSS8/SLC9A1/KIF5B/DLG1/STOM/ACTN4/SLC5A3/ATP1A1/ATP6V1B1/FXYD3 20 GO:0021987 cerebral cortex development 12/742 114/18722 0.00188179739378975 0.0238696842851018 LRP1/ADGRG1/SLC2A1/LAMB1/SLC38A2/RTN4/TACC2/GLI3/NF1/TRA2B/CELF1/RHOA 12 GO:0061572 actin filament bundle organization 15/742 161/18722 0.00188444875935014 0.0238696842851018 HSP90B1/MET/NRP1/TACSTD2/PFN1/SLC9A1/ITGB5/ACTG1/WASF2/ROCK1/PPP1R9A/ID1/S100A10/CDC42/RHOA 15 GO:1901990 regulation of mitotic cell cycle phase transition 23/742 299/18722 0.00193928041566791 0.0244684892231414 EGFR/APP/DUSP1/SOX4/RPL26/ADAMTS1/PBX1/PRKDC/ZFP36L1/TPR/BRD4/ANXA1/DDB1/EIF4G1/DLG1/CTDSPL/BRD7/NEK6/RAB11A/ANAPC11/UBE2C/PSME2/LCMT1 23 GO:0001954 positive regulation of cell-matrix adhesion 8/742 58/18722 0.00194658223981672 0.0244684892231414 DAG1/UTRN/IQGAP1/NRP1/FERMT1/CDK6/ROCK1/S100A10 8 GO:0043666 regulation of phosphoprotein phosphatase activity 8/742 58/18722 0.00194658223981672 0.0244684892231414 HSP90B1/SLC39A10/BOD1L1/PPP1R15A/ROCK1/CALM1/CALM2/CSNK2B 8 GO:0061564 axon development 32/742 467/18722 0.00195742990371357 0.0245423952394544 NRP2/LRP1/GRN/LAMA5/APP/ITGB1/DAG1/GOLGA4/SEMA6A/MYCBP2/MACF1/BSG/RPL24/EPHB4/SEMA6D/ANK3/RTN4/NRP1/BMP7/PTPRF/JAM3/ISL1/FOLR1/GLI3/KIF5B/MTR/USP9X/GATA3/SIAH1/NREP/RAB11A/DYNLT1 32 GO:0007431 salivary gland development 6/742 34/18722 0.00197579317002408 0.0246475208583812 LAMA5/DAG1/NRP1/BMP7/CDC42/TGM2 6 GO:0051085 chaperone cofactor-dependent protein refolding 6/742 34/18722 0.00197579317002408 0.0246475208583812 HSPA5/HSPA1A/HSPA1B/DNAJB14/DNAJB1/PTGES3 6 GO:0070302 regulation of stress-activated protein kinase signaling cascade 17/742 195/18722 0.00199862741145616 0.0248695703087996 EGFR/APP/GADD45B/DUSP1/IGF1R/ARL6IP5/DLG1/EMC10/NCOR1/PPIA/RB1CC1/RNF13/MARVELD3/GADD45G/CDC42/PDCD4/SDCBP 17 GO:1901989 positive regulation of cell cycle phase transition 12/742 115/18722 0.00202721354031106 0.0251618967063735 EGFR/APP/ADAMTS1/PBX1/PPP1R10/NPM1/BRD4/ANXA1/EIF4G1/RAB11A/ANAPC11/UBE2C 12 GO:0030522 intracellular receptor signaling pathway 21/742 265/18722 0.00209184709444941 0.0256998127153453 UFL1/ISL1/NR2F2/CALR/ESRRA/HSPA1A/ARID1A/ACTN4/HSPA1B/PUM1/DDX17/NCOR1/FOXP1/NFKBIA/CITED2/DDX5/NR2F6/PARP1/PTGES3/RHOA/LBH 21 GO:0033627 cell adhesion mediated by integrin 9/742 72/18722 0.00209681980179889 0.0256998127153453 FBN1/ITGB4/ITGAV/ITGB1/PLPP3/DPP4/JAM3/FERMT1/ITGB5 9 GO:0042273 ribosomal large subunit biogenesis 9/742 72/18722 0.00209681980179889 0.0256998127153453 RPLP0/RPL23A/RPL6/RPL14/RPL7/RPL24/RPL26/NPM1/RPL3 9 GO:1903036 positive regulation of response to wounding 9/742 72/18722 0.00209681980179889 0.0256998127153453 LRP1/GRN/ITGB1/CLDN4/KANK1/PLPP3/FERMT1/ANXA1/ACTG1 9 GO:0014031 mesenchymal cell development 10/742 86/18722 0.00210333727998698 0.0256998127153453 NRP2/LAMA5/SEMA6A/SEMA6D/NRP1/BMP7/ISL1/FOLR1/CITED2/HES1 10 GO:0048864 stem cell development 10/742 86/18722 0.00210333727998698 0.0256998127153453 NRP2/LAMA5/SEMA6A/SEMA6D/NRP1/BMP7/ISL1/FOLR1/CITED2/HES1 10 GO:0006913 nucleocytoplasmic transport 23/742 301/18722 0.0021121708425972 0.0256998127153453 CDH1/RPL23/PPP1R10/NPM1/TPR/FERMT1/CALR/GLI3/PABPN1/UPF2/AKAP13/RANBP2/HNRNPA1/NEMF/TCF7L2/THOC2/PTPN14/TXN/NFKBIA/KPNB1/RAN/YWHAE/SSB 23 GO:0051169 nuclear transport 23/742 301/18722 0.0021121708425972 0.0256998127153453 CDH1/RPL23/PPP1R10/NPM1/TPR/FERMT1/CALR/GLI3/PABPN1/UPF2/AKAP13/RANBP2/HNRNPA1/NEMF/TCF7L2/THOC2/PTPN14/TXN/NFKBIA/KPNB1/RAN/YWHAE/SSB 23 GO:0010976 positive regulation of neuron projection development 15/742 163/18722 0.00212729710515027 0.0258202646177945 HSPA5/LRP1/GRN/ITGA6/TENM3/SERPINF1/IQGAP1/BMP7/S100A9/KIDINS220/P3H1/PPP1R9A/CREB3L2/DHX36/DYNLT1 15 GO:1902850 microtubule cytoskeleton organization involved in mitosis 14/742 147/18722 0.00214513658119771 0.0259729772331291 ITGB1/DYNC1H1/GJA1/TACC2/TPR/HSPA1A/HSPA1B/KPNB1/CLTC/RAN/NEK6/RHOA/RAB11A/DYNLT1 14 GO:0021782 glial cell development 12/742 116/18722 0.00218170177669986 0.0262425832170078 EGFR/ITGB4/LRP1/GRN/APP/DAG1/PLEC/SOX4/CDK6/NF1/NCSTN/S100A9 12 GO:0030518 intracellular steroid hormone receptor signaling pathway 12/742 116/18722 0.00218170177669986 0.0262425832170078 UFL1/ISL1/CALR/ARID1A/DDX17/NCOR1/FOXP1/DDX5/PARP1/PTGES3/RHOA/LBH 12 GO:0009416 response to light stimulus 24/742 320/18722 0.00218725857018204 0.0262425832170078 EGFR/FOS/APP/ITGB1/JUND/DUSP1/RPL26/NPM1/MME/DDB1/NF1/NMT1/TP53I13/CDS1/GNAQ/SDF4/DHX36/EIF2AK4/CIRBP/NR2F6/GPX1/PARP1/DYNLRB1/YY1 24 GO:0018196 peptidyl-asparagine modification 5/742 24/18722 0.00218865268935369 0.0262425832170078 RPN2/DDOST/TUSC3/FUT8/RPN1 5 GO:0032412 regulation of ion transmembrane transporter activity 21/742 267/18722 0.00229014217719063 0.0272936813280504 AKAP9/AHNAK/TCAF1/APP/ITGB1/UTRN/CAV1/ANK3/C4orf3/GSTO1/TMSB4X/SLC9A1/KIF5B/DLG1/STOM/ACTN4/VAMP2/CALM1/FXYD3/CALM2/YWHAE 21 GO:0048041 focal adhesion assembly 10/742 87/18722 0.00229410662152522 0.0272936813280504 LRP1/MACF1/IQGAP1/NRP1/SLC9A1/ACTG1/PTPRA/ROCK1/S100A10/RHOA 10 GO:0032350 regulation of hormone metabolic process 6/742 35/18722 0.00230588747765318 0.0272936813280504 EGR1/POR/ATP1A1/TCF7L2/ADM/GATA3 6 GO:0035633 maintenance of blood-brain barrier 6/742 35/18722 0.00230588747765318 0.0272936813280504 ITGB1/LAMC1/GJA1/LSR/JAM3/ACTG1 6 GO:0097421 liver regeneration 6/742 35/18722 0.00230588747765318 0.0272936813280504 EGFR/RPS16/RPL19/SRSF5/GLI3/CSNK2B 6 GO:0072089 stem cell proliferation 9/742 73/18722 0.00230946534314272 0.0272936813280504 FBLN1/N4BP2L2/RNF43/GJA1/ZFP36L1/FERMT1/ZNRF3/LTBP3/CCNE1 9 GO:0033599 regulation of mammary gland epithelial cell proliferation 4/742 15/18722 0.00235447794159103 0.0274967400270915 RTN4/KDM5B/GATA3/GPX1 4 GO:0045475 locomotor rhythm 4/742 15/18722 0.00235447794159103 0.0274967400270915 EGR1/ZFHX3/NAGLU/NCOR1 4 GO:0086069 bundle of His cell to Purkinje myocyte communication 4/742 15/18722 0.00235447794159103 0.0274967400270915 DSP/DSG2/DSC2/GJA5 4 GO:1905146 lysosomal protein catabolic process 4/742 15/18722 0.00235447794159103 0.0274967400270915 LRP2/LRP1/LAMP2/CLN3 4 GO:2001028 positive regulation of endothelial cell chemotaxis 4/742 15/18722 0.00235447794159103 0.0274967400270915 MET/TMSB4X/LGMN/HSPB1 4 GO:0043010 camera-type eye development 24/742 322/18722 0.00237234472992688 0.0276400541647141 FBN2/ATP2B1/FBN1/EFEMP1/TENM3/SERPINF1/RPL24/FLT1/LRP5/NAGLU/NRP1/BMP7/ATP2B4/CRYBG3/GLI3/NF1/FAT1/DLG1/MAN2A1/KDM5B/CITED2/GATA3/OBSL1/YY1 24 GO:0009306 protein secretion 26/742 359/18722 0.00237878763073096 0.0276499079901434 EGFR/LRP1/KCNN4/WLS/ERP29/MYH10/SOX4/GJA1/DPP4/DYNLL1/PDIA4/LRP5/ISL1/MIA3/FRMD4A/ANXA1/KIF5B/CANX/P3H1/TCF7L2/SYT7/PPIA/GNPTAB/SLC16A1/HMGN3/PHPT1 26 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 8/742 60/18722 0.00242457971665153 0.0280501728343292 RBM25/TRA2B/HNRNPA1/DDX17/SRSF6/CELF1/DDX5/MBNL3 8 GO:0061951 establishment of protein localization to plasma membrane 8/742 60/18722 0.00242457971665153 0.0280501728343292 GOLGA4/MACF1/ANK3/SPTBN1/VAMP2/KRT18/CLN3/RAB11A 8 GO:1905039 carboxylic acid transmembrane transport 14/742 149/18722 0.00243288868641102 0.0280805376422206 LRP2/SLC2A1/ITGB1/SLC3A2/SLC38A1/SLC43A2/SLC38A2/SLC1A5/SLC19A1/SLC38A10/ARL6IP5/SLC38A9/FOLR1/SLC16A1 14 GO:0035592 establishment of protein localization to extracellular region 26/742 360/18722 0.00247068564531543 0.028450319552117 EGFR/LRP1/KCNN4/WLS/ERP29/MYH10/SOX4/GJA1/DPP4/DYNLL1/PDIA4/LRP5/ISL1/MIA3/FRMD4A/ANXA1/KIF5B/CANX/P3H1/TCF7L2/SYT7/PPIA/GNPTAB/SLC16A1/HMGN3/PHPT1 26 GO:0140014 mitotic nuclear division 22/742 287/18722 0.00250997425793218 0.0288355182190348 RPL24/DUSP1/ATRX/LRP5/BMP7/TPR/HSPA1A/PHIP/NIPBL/HSPA1B/OBSL1/KPNB1/RAN/CDC42/NEK6/RHOA/IGF2/RAB11A/ANAPC11/UBE2C/RANBP1/LCMT1 22 GO:0030203 glycosaminoglycan metabolic process 12/742 118/18722 0.00251956949097229 0.02887859230952 ITIH5/CHPF/HEXA/NAGLU/FUCA1/B4GAT1/GUSB/GNS/B3GAT3/GLB1/CLTC/HEXB 12 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 9/742 74/18722 0.0025388959159235 0.0290327449644956 UFL1/ISL1/CALR/NCOR1/FOXP1/DDX5/PARP1/RHOA/LBH 9 GO:1903825 organic acid transmembrane transport 14/742 150/18722 0.00258827241855913 0.029529020202499 LRP2/SLC2A1/ITGB1/SLC3A2/SLC38A1/SLC43A2/SLC38A2/SLC1A5/SLC19A1/SLC38A10/ARL6IP5/SLC38A9/FOLR1/SLC16A1 14 GO:0033119 negative regulation of RNA splicing 5/742 25/18722 0.00264772736162516 0.0301377261899269 RPS13/RPS26/NPM1/SRSF7/SRSF6 5 GO:0015804 neutral amino acid transport 7/742 48/18722 0.00266748947800697 0.0302233899572349 SLC3A2/SLC38A1/SLC43A2/SLC38A2/SLC1A5/SLC38A9/SERINC3 7 GO:0032527 protein exit from endoplasmic reticulum 7/742 48/18722 0.00266748947800697 0.0302233899572349 HSP90B1/GCC2/CD81/OS9/FAF2/HM13/BCAP31 7 GO:0009743 response to carbohydrate 20/742 253/18722 0.00271422012692317 0.0306824883913054 LRP1/LDHA/SERPINF1/SOX4/GJA1/EGR1/CTSV/ZFP36L1/DYNLL1/COLEC12/LRP5/IGF1R/KIF5B/TRA2B/TCF7L2/VAMP2/KRT18/HMGN3/RHOA/PHPT1 20 GO:0030336 negative regulation of cell migration 25/742 344/18722 0.00272827278467161 0.0307709304937848 LRP1/TCAF1/CDH1/ADGRG1/DAG1/RHOB/SERPINF1/KANK1/DUSP1/MIF/SEMA6D/GJA1/DPP4/DLG5/TACSTD2/ATP2B4/NR2F2/CALR/MIA3/NF1/GNA12/CITED2/MARVELD3/RHOA/CSNK2B 25 GO:0006403 RNA localization 17/742 201/18722 0.00274836054092387 0.0308243876637575 ZFP36L1/NPM1/TPR/PABPN1/UPF2/RANBP2/YBX1/HNRNPA1/SRSF7/THOC2/DHX36/RAN/YY1/IGF2BP3/SSB/EIF5A/CCT3 17 GO:0048754 branching morphogenesis of an epithelial tube 14/742 151/18722 0.00275173177322208 0.0308243876637575 LAMA5/DAG1/MET/LGR4/PBX1/DLG5/LRP5/NRP1/BMP7/TACSTD2/GLI3/MAGED1/DLG1/KDM5B 14 GO:2001236 regulation of extrinsic apoptotic signaling pathway 14/742 151/18722 0.00275173177322208 0.0308243876637575 ITGAV/ITGA6/PDIA3/CAV1/NRP1/HSPA1A/PHIP/PMAIP1/HSPA1B/TIMP3/TCF7L2/RB1CC1/GPX1/SIAH2 14 GO:0048872 homeostasis of number of cells 21/742 272/18722 0.00285649891859536 0.0318751255248549 ADGRG1/RPS6/UFL1/LGR4/TGFBR3/SOX4/PRKDC/ZFP36L1/JAM3/HSPA1A/ANXA1/CDK6/FSTL1/NCSTN/PMAIP1/HSPA1B/RPS17/CITED2/GATA3/EPAS1/ADAR 21 GO:0009746 response to hexose 18/742 219/18722 0.00285843736994144 0.0318751255248549 LRP1/LDHA/SERPINF1/SOX4/GJA1/EGR1/CTSV/DYNLL1/LRP5/IGF1R/KIF5B/TRA2B/TCF7L2/VAMP2/KRT18/HMGN3/RHOA/PHPT1 18 GO:0051896 regulation of protein kinase B signaling 16/742 185/18722 0.00289391783453678 0.0321805491244431 LRP2/EGFR/ITGB1/DAG1/MET/RTN4/IGF1R/MYDGF/DLG1/TPBG/TCF7L2/DDIT3/TXN/GATA3/GPX1/IGF2 16 GO:0030218 erythrocyte differentiation 12/742 120/18722 0.00289885513367959 0.0321805491244431 RPS6/UFL1/TGFBR3/PRKDC/ZFP36L1/HSPA1A/CDK6/HSPA1B/CITED2/GATA3/EPAS1/ADAR 12 GO:0045727 positive regulation of translation 13/742 136/18722 0.00294625019189101 0.0324688105227505 SOX4/RPL26/PRKDC/PPP1R15A/NPM1/EIF4G1/DHX36/EIF2AK4/LARP1/CIRBP/PKM/RHOA/EIF5A 13 GO:0030901 midbrain development 10/742 90/18722 0.00295111253536741 0.0324688105227505 HSPA5/WLS/DYNLL1/DLG5/CALM1/HES1/CDC42/RHOA/CALM2/YWHAE 10 GO:0035304 regulation of protein dephosphorylation 10/742 90/18722 0.00295111253536741 0.0324688105227505 HSP90B1/SLC39A10/BOD1L1/PPP1R15A/ROCK1/PPIA/CALM1/CALM2/CSNK2B/YWHAE 10 GO:0046849 bone remodeling 10/742 90/18722 0.00295111253536741 0.0324688105227505 EGFR/TFRC/LGR4/GJA1/ATP6AP1/LRP5/SUCO/NF1/LTBP3/SYT7 10 GO:0045936 negative regulation of phosphate metabolic process 30/742 441/18722 0.00296591867144109 0.0325489087398879 FBLN1/LRP1/PLEC/GADD45B/BOD1L1/DUSP1/CAV1/DUSP6/PRKDC/PLPP3/DYNLL1/LRP5/PPP1R15A/NPM1/BMP7/NR2F2/NF1/EIF4G1/ROCK1/NCOR1/GNAQ/CTDSPL/PPIA/CALM1/HSPB1/ADAR/PARP1/CALM2/PDCD4/YWHAE 30 GO:0060485 mesenchyme development 22/742 291/18722 0.00297157041329746 0.0325489087398879 NRP2/LAMA5/DAG1/SEMA6A/TGFBR3/SEMA6D/ZFP36L1/DLG5/RTN4/NRP1/BMP7/ISL1/FOLR1/ROCK1/DDX17/TCF7L2/CITED2/GATA3/DDX5/HES1/PDCD4/SDCBP 22 GO:0070849 response to epidermal growth factor 7/742 49/18722 0.00300773739344407 0.0325691544591728 EGFR/EEF1A1/IQGAP1/ZFP36L1/TPR/PTPN12/ID1 7 GO:0072091 regulation of stem cell proliferation 7/742 49/18722 0.00300773739344407 0.0325691544591728 FBLN1/N4BP2L2/GJA1/ZFP36L1/FERMT1/LTBP3/CCNE1 7 GO:0006937 regulation of muscle contraction 15/742 169/18722 0.00301662114190787 0.0325691544591728 AKAP9/ATP2B1/CAV1/DSP/DSG2/DSC2/GSTO1/GJA5/SLC9A1/ENO1/DLG1/ATP1A1/CALM1/RHOA/CALM2 15 GO:0005980 glycogen catabolic process 4/742 16/18722 0.00304176781970663 0.0325691544591728 GAA/AGL/RB1CC1/PYGL 4 GO:0017014 protein nitrosylation 4/742 16/18722 0.00304176781970663 0.0325691544591728 GAPDH/ATP2B4/S100A9/TXN 4 GO:0018119 peptidyl-cysteine S-nitrosylation 4/742 16/18722 0.00304176781970663 0.0325691544591728 GAPDH/ATP2B4/S100A9/TXN 4 GO:0035751 regulation of lysosomal lumen pH 4/742 16/18722 0.00304176781970663 0.0325691544591728 GRN/ATP6AP2/TMEM165/CLN3 4 GO:0099010 modification of postsynaptic structure 4/742 16/18722 0.00304176781970663 0.0325691544591728 MYH10/PFN1/CDC42/RHOA 4 GO:2000651 positive regulation of sodium ion transmembrane transporter activity 4/742 16/18722 0.00304176781970663 0.0325691544591728 ANK3/SLC9A1/KIF5B/ACTN4 4 GO:0140115 export across plasma membrane 9/742 76/18722 0.00305178735751387 0.0325691544591728 ATP2B1/GJA1/SLC9A1/SLC40A1/DLG1/ATP1A1/CALM1/CALM2/YWHAE 9 GO:0071478 cellular response to radiation 16/742 186/18722 0.00305339539043145 0.0325691544591728 HSPA5/RHOB/RPL26/EGR1/NPM1/MME/DDB1/NIPBL/NMT1/TMEM109/DHX36/EIF2AK4/GATA3/PARP1/ADIRF/YY1 16 GO:0006936 muscle contraction 25/742 347/18722 0.00305776949591911 0.0325691544591728 AKAP9/ATP2B1/GAA/ALDOA/UTRN/CAV1/GJA1/DSP/DSG2/DSC2/GSTO1/ATP2B4/GJA5/SLC9A1/PABPN1/ENO1/ASPH/DLG1/ROCK1/SSPN/ATP1A1/CALM1/TPM4/RHOA/CALM2 25 GO:0032409 regulation of transporter activity 23/742 310/18722 0.00306150269601838 0.0325691544591728 AKAP9/AHNAK/TCAF1/APP/ITGB1/UTRN/CAV1/GJA1/ANK3/C4orf3/GSTO1/TMSB4X/SLC9A1/KIF5B/DLG1/STOM/ACTN4/SLC5A3/VAMP2/CALM1/FXYD3/CALM2/YWHAE 23 GO:0010563 negative regulation of phosphorus metabolic process 30/742 442/18722 0.00306572000476019 0.0325691544591728 FBLN1/LRP1/PLEC/GADD45B/BOD1L1/DUSP1/CAV1/DUSP6/PRKDC/PLPP3/DYNLL1/LRP5/PPP1R15A/NPM1/BMP7/NR2F2/NF1/EIF4G1/ROCK1/NCOR1/GNAQ/CTDSPL/PPIA/CALM1/HSPB1/ADAR/PARP1/CALM2/PDCD4/YWHAE 30 GO:0001704 formation of primary germ layer 12/742 121/18722 0.00310515426483753 0.0328468138507439 ITGB4/ITGAV/LAMB1/ITGB1/COL4A2/WLS/DUSP1/GJA1/MMP15/BMP7/ITGB5/RTF1 12 GO:0003206 cardiac chamber morphogenesis 12/742 121/18722 0.00310515426483753 0.0328468138507439 LRP2/NRP2/TGFBR3/SOX4/DSP/ADAMTS1/NRP1/BMP7/ISL1/CITED2/GATA3/HES1 12 GO:0090090 negative regulation of canonical Wnt signaling pathway 13/742 137/18722 0.00314041659434168 0.0331488418291621 CAV1/EGR1/TLE4/ISL1/FERMT1/GLI3/ZNRF3/CTNND1/TPBG/TCF7L2/DDIT3/SIAH2/NOTUM 13 GO:0006027 glycosaminoglycan catabolic process 5/742 26/18722 0.00317270215475441 0.0332429609263195 NAGLU/FUCA1/GUSB/GNS/GLB1 5 GO:0060037 pharyngeal system development 5/742 26/18722 0.00317270215475441 0.0332429609263195 BMP7/ISL1/FOLR1/GATA3/HES1 5 GO:0030178 negative regulation of Wnt signaling pathway 15/742 170/18722 0.00319100624141846 0.0332429609263195 LRP1/CAV1/RNF43/EGR1/TLE4/ISL1/FERMT1/GLI3/ZNRF3/CTNND1/TPBG/TCF7L2/DDIT3/SIAH2/NOTUM 15 GO:0001657 ureteric bud development 10/742 91/18722 0.00320070200716796 0.0332429609263195 LAMA5/LGR4/PBX1/BMP7/TACSTD2/GLI3/MAGED1/DLG1/GATA3/HES1 10 GO:0014033 neural crest cell differentiation 10/742 91/18722 0.00320070200716796 0.0332429609263195 NRP2/LAMA5/SEMA6A/SEMA6D/NRP1/BMP7/ISL1/FOLR1/CITED2/HES1 10 GO:0072080 nephron tubule development 10/742 91/18722 0.00320070200716796 0.0332429609263195 LAMA5/LGR4/PBX1/TACSTD2/GLI3/MAGED1/DLG1/IRX2/GATA3/HES1 10 GO:0140694 non-membrane-bounded organelle assembly 26/742 367/18722 0.00320263201671166 0.0332429609263195 RPLP0/RPL23A/KRT19/ITGB1/PRRC2C/RPL6/DYNC1H1/PLEC/RPL24/PRKDC/KRT8/NPM1/TPR/RPL3/HSPA1A/ACTG1/AKAP13/HSPA1B/NCOR1/CDS1/CIRBP/OBSL1/KPNB1/NEK6/RHOA/RAB11A 26 GO:1901888 regulation of cell junction assembly 17/742 204/18722 0.00320316789492471 0.0332429609263195 LRP1/APP/MACF1/CAV1/IQGAP1/GJA1/DLG5/NRP1/SLC9A1/ACTG1/EIF4G1/PTPRA/ROCK1/PPP1R9A/TPBG/S100A10/RHOA 17 GO:0051403 stress-activated MAPK cascade 19/742 239/18722 0.00321601567513685 0.0333063258599079 EGFR/APP/GADD45B/DUSP1/HACD3/ZFP36L1/IGF1R/ARL6IP5/DLG1/EMC10/DUSP9/NCOR1/PPIA/RB1CC1/MARVELD3/GADD45G/CDC42/PDCD4/SDCBP 19 GO:0015931 nucleobase-containing compound transport 18/742 222/18722 0.00330561385928439 0.0341626202193826 GJA1/SLC19A1/ZFP36L1/NPM1/TPR/SLC25A36/PABPN1/UPF2/RANBP2/YBX1/HNRNPA1/SRSF7/THOC2/SLC35B4/RAN/IGF2BP3/SSB/EIF5A 18 GO:0031016 pancreas development 9/742 77/18722 0.00333713941668132 0.0344164273870683 MET/WLS/SOX4/ISL1/ANXA1/CDK6/TCF7L2/HES1/IGF2 9 GO:0070085 glycosylation 19/742 240/18722 0.0033670313167364 0.0346523639680788 RPN2/EXTL2/GALNT11/TRIP11/DDOST/TMEM59/B4GAT1/MAN2A1/B3GAT3/C1GALT1/MAN1A2/MOGS/TUSC3/C1GALT1C1/GXYLT1/TET2/TMEM165/FUT8/RPN1 19 GO:0007548 sex differentiation 21/742 276/18722 0.00339042330016691 0.0348205636233358 LRP2/HSPA5/ADGRG1/SF1/ATRX/LGR4/DHCR24/ADAMTS1/PBX1/CTSV/NR2F2/KDM5A/NIPBL/ARID5B/CITED2/GATA3/RHOBTB3/PRDX4/EIF2S2/CYP19A1/CGA 21 GO:0072163 mesonephric epithelium development 10/742 92/18722 0.00346680294435108 0.0354575704867377 LAMA5/LGR4/PBX1/BMP7/TACSTD2/GLI3/MAGED1/DLG1/GATA3/HES1 10 GO:0072164 mesonephric tubule development 10/742 92/18722 0.00346680294435108 0.0354575704867377 LAMA5/LGR4/PBX1/BMP7/TACSTD2/GLI3/MAGED1/DLG1/GATA3/HES1 10 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway 6/742 38/18722 0.00354689442278332 0.0361934111694281 ISL1/CALR/NCOR1/FOXP1/RHOA/LBH 6 GO:0003231 cardiac ventricle development 12/742 123/18722 0.0035534017038811 0.0361934111694281 LRP2/TGFBR3/SOX4/DSP/TRIP11/LMO4/ISL1/GJA5/HECTD1/CITED2/GATA3/HES1 12 GO:0030837 negative regulation of actin filament polymerization 8/742 64/18722 0.00365285922690494 0.0371298859689514 KANK1/SPTAN1/PFN1/TMSB4X/SPTBN1/TRIOBP/KANK4/CAPZB 8 GO:1901987 regulation of cell cycle phase transition 27/742 390/18722 0.00369652557738921 0.0374965838856318 EGFR/APP/DUSP1/SOX4/RPL26/ADAMTS1/PBX1/PRKDC/ZFP36L1/PPP1R10/NPM1/TPR/ATP2B4/BRD4/ANXA1/DDB1/EIF4G1/DLG1/CTDSPL/EIF2AK4/BRD7/NEK6/RAB11A/ANAPC11/UBE2C/PSME2/LCMT1 27 GO:0051591 response to cAMP 10/742 93/18722 0.00375016897580746 0.0378851426185867 JUN/AKAP9/FOS/HSPA5/APP/LDHA/FOSB/BSG/DUSP1/ZFP36L1 10 GO:1901992 positive regulation of mitotic cell cycle phase transition 10/742 93/18722 0.00375016897580746 0.0378851426185867 EGFR/APP/ADAMTS1/PBX1/BRD4/ANXA1/EIF4G1/RAB11A/ANAPC11/UBE2C 10 GO:0006694 steroid biosynthetic process 15/742 173/18722 0.00376452566500737 0.0379169613905957 SF1/DHCR24/SLC27A2/PBX1/EGR1/POR/PRLR/ATP1A1/MBTPS1/ADM/ASAH1/CYP11A1/HSD17B1/CYP19A1/CGA 15 GO:0000027 ribosomal large subunit assembly 5/742 27/18722 0.00376866964428795 0.0379169613905957 RPLP0/RPL23A/RPL6/RPL24/RPL3 5 GO:0046850 regulation of bone remodeling 7/742 51/18722 0.00378679275007035 0.0380218621653405 EGFR/TFRC/ATP6AP1/SUCO/NF1/LTBP3/SYT7 7 GO:0034284 response to monosaccharide 18/742 225/18722 0.00380940823700849 0.0381713523140405 LRP1/LDHA/SERPINF1/SOX4/GJA1/EGR1/CTSV/DYNLL1/LRP5/IGF1R/KIF5B/TRA2B/TCF7L2/VAMP2/KRT18/HMGN3/RHOA/PHPT1 18 GO:0031346 positive regulation of cell projection organization 25/742 353/18722 0.00381847394047295 0.0381847394047295 HSPA5/LRP1/GRN/ITGA6/GOLGA4/TENM3/SERPINF1/MACF1/IQGAP1/NRP1/BMP7/CUX1/PFN1/S100A9/KIDINS220/P3H1/WASF2/PPP1R9A/CREB3L2/DHX36/OBSL1/CDC42/RAB11A/EPS8L1/DYNLT1 25 GO:0009251 glucan catabolic process 4/742 17/18722 0.00385429030315372 0.0384650385809684 GAA/AGL/RB1CC1/PYGL 4 GO:0002573 myeloid leukocyte differentiation 17/742 208/18722 0.00390494689115982 0.0388920113756643 JUN/FBN1/FOS/APP/TFRC/ZFP36L1/ATP6AP1/ESRRA/CD81/CDK6/JUNB/FOXP1/CITED2/GATA3/PARP1/CDC42/DHRS2 17 GO:0007030 Golgi organization 14/742 157/18722 0.00391997520736682 0.0389631338518956 AKAP9/GOLGB1/LMAN1/TMED9/TRIP11/GCC2/ARHGAP21/TMED4/LMAN2/SURF4/TMED1/HUWE1/OBSL1/CDC42 14 GO:0015711 organic anion transport 25/742 354/18722 0.00395956075049508 0.0391066648224691 LRP2/SLC26A2/SLC2A1/ITGB1/PSAP/SLC22A11/SLC3A2/SLC38A1/SLC43A2/SLC38A2/GJA1/SLC1A5/SLC19A1/SLC52A1/ARL6IP5/SLC38A9/FOLR1/ANXA1/SLC16A12/SLC52A3/SERINC3/SLC35B4/SLC52A2/SLC16A1/CLN3 25 GO:0010038 response to metal ion 26/742 373/18722 0.00396873324056525 0.0391066648224691 JUN/EGFR/FOS/HSPA5/CDH1/APP/JUND/SERPINF1/FOSB/BSG/FUS/DUSP1/CAV1/IQGAP1/SOD3/ANK3/CALR/LGMN/NCSTN/JUNB/SYT7/CALM1/PARP1/HSD17B1/CALM2/CACYBP 26 GO:0000245 spliceosomal complex assembly 9/742 79/18722 0.00397053455978637 0.0391066648224691 SF1/SCAF11/SRSF5/LUC7L3/SRSF6/CELF1/SF3B1/SNRPD2/SNRPC 9 GO:0032272 negative regulation of protein polymerization 9/742 79/18722 0.00397053455978637 0.0391066648224691 KANK1/SPTAN1/PFN1/TMSB4X/SPTBN1/TRIOBP/KANK4/CAPZB/VDAC2 9 GO:0072009 nephron epithelium development 11/742 109/18722 0.00397399711353836 0.0391066648224691 LAMA5/IQGAP1/LGR4/PBX1/TACSTD2/GLI3/MAGED1/DLG1/IRX2/GATA3/HES1 11 GO:0009101 glycoprotein biosynthetic process 23/742 317/18722 0.00402848173299136 0.0395403800568623 RPN2/EXTL2/CHPF/GALNT11/ITM2B/TRIP11/DDOST/TMEM59/B4GAT1/NCSTN/MAN2A1/B3GAT3/C1GALT1/MAN1A2/MOGS/TUSC3/TCF7L2/C1GALT1C1/GXYLT1/TET2/TMEM165/FUT8/RPN1 23 GO:0010466 negative regulation of peptidase activity 20/742 262/18722 0.00403407926086206 0.0395403800568623 ITIH5/GAPDH/APLP2/SPINT1/LRP1/APP/CRIM1/SPINT2/SERPINF1/DHCR24/SERPINH1/POR/ROCK1/CST3/TIMP3/GPX1/TFPI2/SIAH2/SERPINB9/SERPINB1 20 GO:1990830 cellular response to leukemia inhibitory factor 10/742 94/18722 0.00405156821089835 0.03957788373608 NRP2/RPS16/TFRC/TLE4/SRSF7/RIF1/ARID5B/KDM5B/PCOLCE2/CACYBP 10 GO:0051084 'de novo' posttranslational protein folding 6/742 39/18722 0.00405392898187378 0.03957788373608 HSPA5/HSPA1A/HSPA1B/DNAJB14/DNAJB1/PTGES3 6 GO:0052548 regulation of endopeptidase activity 29/742 432/18722 0.00415859319908605 0.0404820558412699 ITIH5/GAPDH/APLP2/SPINT1/APP/CRIM1/CTSD/SPINT2/SERPINF1/DHCR24/SERPINH1/POR/ARL6IP5/ASPH/LGMN/NCSTN/S100A9/PMAIP1/ROCK1/CST3/TIMP3/GPX1/TFPI2/SIAH2/BCAP31/SERPINB9/SERPINB1/RHOA/PSME2 29 GO:0032872 regulation of stress-activated MAPK cascade 16/742 192/18722 0.00417000732348698 0.0404820558412699 EGFR/APP/GADD45B/DUSP1/IGF1R/ARL6IP5/DLG1/EMC10/NCOR1/PPIA/RB1CC1/MARVELD3/GADD45G/CDC42/PDCD4/SDCBP 16 GO:0007249 I-kappaB kinase/NF-kappaB signaling 21/742 281/18722 0.0041728990307264 0.0404820558412699 GAPDH/UFL1/TFRC/WLS/GJA1/HACD3/BRD4/TMED4/ASH1L/AKAP13/SLC44A2/ROCK1/ERC1/DHX36/NFKBIA/HSPB1/USP10/PRDX4/TGM2/NEK6/RHOA 21 GO:0007411 axon guidance 18/742 227/18722 0.00417932155446309 0.0404820558412699 NRP2/LRP1/LAMA5/APP/DAG1/SEMA6A/MYCBP2/BSG/RPL24/EPHB4/SEMA6D/NRP1/BMP7/ISL1/GLI3/KIF5B/GATA3/SIAH1 18 GO:0048771 tissue remodeling 15/742 175/18722 0.00419176053840444 0.04052308622254 EGFR/TFRC/CAV1/LGR4/GJA1/ATP6AP1/LRP5/SUCO/NF1/LTBP3/ROCK1/CST3/SYT7/EPAS1/TGM2 15 GO:0003012 muscle system process 30/742 452/18722 0.00423127745412581 0.040825216061292 AKAP9/ATP2B1/DAG1/GAA/ALDOA/UTRN/CAV1/IL6ST/GJA1/DSP/DSG2/DSC2/GSTO1/ATP2B4/GJA5/SLC9A1/PABPN1/ENO1/ASPH/DLG1/AKAP13/ROCK1/SSPN/ATP1A1/CALM1/PARP1/YY1/TPM4/RHOA/CALM2 30 GO:0007422 peripheral nervous system development 9/742 80/18722 0.00432058463018152 0.0415246849671142 ITGB4/DAG1/PLEC/ISL1/GPC1/NF1/SLC5A3/ERBB3/CITED2 9 GO:0120193 tight junction organization 9/742 80/18722 0.00432058463018152 0.0415246849671142 CLDN4/SVEP1/PLEC/GJA1/LSR/ACTG1/DLG1/ROCK1/MARVELD3 9 GO:1990823 response to leukemia inhibitory factor 10/742 95/18722 0.00437178257943369 0.0418856473055736 NRP2/RPS16/TFRC/TLE4/SRSF7/RIF1/ARID5B/KDM5B/PCOLCE2/CACYBP 10 GO:0097485 neuron projection guidance 18/742 228/18722 0.0043751000019587 0.0418856473055736 NRP2/LRP1/LAMA5/APP/DAG1/SEMA6A/MYCBP2/BSG/RPL24/EPHB4/SEMA6D/NRP1/BMP7/ISL1/GLI3/KIF5B/GATA3/SIAH1 18 GO:0032868 response to insulin 20/742 264/18722 0.00439025079454915 0.0419493983076843 ATP2B1/SLC2A1/KANK1/EGR1/PRKDC/ZFP36L1/IGF1R/SRSF5/ESRRA/VPS13C/SLC9A1/PHIP/PTPRA/VAMP2/ADM/SRSF6/HADHA/PKM/PARP1/IGF2 20 GO:0003007 heart morphogenesis 19/742 246/18722 0.00440226612581819 0.0419695686378643 LRP2/NRP2/GAA/TGFBR3/SOX4/EPHB4/DSP/ADAMTS1/RTN4/NRP1/BMP7/ISL1/GJA5/FOLR1/NIPBL/CITED2/GATA3/HES1/PDCD4 19 GO:1904062 regulation of cation transmembrane transport 25/742 357/18722 0.00440935346620477 0.0419695686378643 AKAP9/AHNAK/APP/ITGB1/KCNN4/UTRN/CAV1/SLC43A2/ANK3/C4orf3/GSTO1/ATP2B4/TMSB4X/SLC9A1/KIF5B/DLG1/STOM/DIAPH1/ACTN4/VAMP2/CALM1/VDAC1/FXYD3/CALM2/YWHAE 25 GO:0043491 protein kinase B signaling 17/742 211/18722 0.00451055317797983 0.0428502551908084 LRP2/EGFR/ITGB1/DAG1/MET/ZFP36L1/RTN4/IGF1R/MYDGF/DLG1/TPBG/TCF7L2/DDIT3/TXN/GATA3/GPX1/IGF2 17 GO:0035270 endocrine system development 12/742 127/18722 0.00460617826041542 0.0434853483485891 CDH1/SOX4/PBX1/ISL1/ANXA1/CDK6/NF1/ARID5B/CITED2/GATA3/HES1/CGA 12 GO:0014037 Schwann cell differentiation 6/742 40/18722 0.00461261589770459 0.0434853483485891 ITGB4/DAG1/PLEC/GPC1/NF1/ERBB3 6 GO:0030866 cortical actin cytoskeleton organization 6/742 40/18722 0.00461261589770459 0.0434853483485891 PLEC/CALR/DLG1/ROCK1/FMNL2/TLN1 6 GO:0044275 cellular carbohydrate catabolic process 6/742 40/18722 0.00461261589770459 0.0434853483485891 GAA/AGL/TPI1/GUSB/RB1CC1/PYGL 6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 9/742 81/18722 0.00469423592598354 0.0439987509402958 FBN2/FBN1/PEG10/HSPA5/GLG1/CAV1/TGFBR3/LTBP1/HSPA1A 9 GO:0048708 astrocyte differentiation 9/742 81/18722 0.00469423592598354 0.0439987509402958 EGFR/LRP1/GRN/APP/IL6ST/CDK6/NF1/S100A9/HES1 9 GO:0071260 cellular response to mechanical stimulus 9/742 81/18722 0.00469423592598354 0.0439987509402958 EGFR/SLC2A1/DAG1/PLEC/SLC38A2/GJA1/TMEM150C/SLC9A1/ATP1A1 9 GO:0001823 mesonephros development 10/742 96/18722 0.00471160713510455 0.0439987509402958 LAMA5/LGR4/PBX1/BMP7/TACSTD2/GLI3/MAGED1/DLG1/GATA3/HES1 10 GO:0034620 cellular response to unfolded protein 10/742 96/18722 0.00471160713510455 0.0439987509402958 HSPA5/UFL1/PPP1R15A/HSPA1A/OS9/HSPA1B/CREB3L2/ATF6/MBTPS1/DDIT3 10 GO:0009749 response to glucose 17/742 212/18722 0.00472875781166866 0.0440755916785721 LRP1/LDHA/SERPINF1/SOX4/GJA1/EGR1/CTSV/DYNLL1/LRP5/IGF1R/KIF5B/TRA2B/TCF7L2/VAMP2/HMGN3/RHOA/PHPT1 17 GO:0044247 cellular polysaccharide catabolic process 4/742 18/18722 0.00480199738995859 0.0445348755931845 GAA/AGL/RB1CC1/PYGL 4 GO:0061484 hematopoietic stem cell homeostasis 4/742 18/18722 0.00480199738995859 0.0445348755931845 ADGRG1/SOX4/FSTL1/ADAR 4 GO:0015849 organic acid transport 22/742 303/18722 0.00480507868242254 0.0445348755931845 LRP2/SLC26A2/SLC2A1/ITGB1/SLC3A2/SLC38A1/SLC43A2/SLC38A2/GJA1/SLC1A5/SLC27A2/SLC19A1/SLC38A10/ARL6IP5/SLC38A9/FOLR1/ANXA1/CROT/PLIN2/SERINC3/SLC16A1/CLN3 22 GO:0048640 negative regulation of developmental growth 11/742 112/18722 0.00488738776423652 0.0451284029071559 SEMA6A/SEMA6D/GJA1/SLC6A4/RTN4/NRP1/LGMN/ADRB1/CITED2/YY1/CGA 11 GO:1901222 regulation of NIK/NF-kappaB signaling 11/742 112/18722 0.00488738776423652 0.0451284029071559 EGFR/APP/BMP7/CALR/TMSB4X/NFAT5/TRIM44/ACTN4/NFKBIA/RHOA/PDCD4 11 GO:0090287 regulation of cellular response to growth factor stimulus 22/742 304/18722 0.0049930208998861 0.0460177672489503 LRP2/FBN2/FBN1/PEG10/HSPA5/SEMA6A/GLG1/CRIM1/CAV1/TGFBR3/LTBP1/ATP2B4/FERMT1/FOLR1/HSPA1A/FSTL1/GPC1/CITED2/GATA3/HES1/NREP/SDCBP 22 GO:0070252 actin-mediated cell contraction 10/742 97/18722 0.00507184932376476 0.0465705123780631 AKAP9/CAV1/GJA1/DSP/DSG2/DSC2/GJA5/SLC9A1/DLG1/ATP1A1 10 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 10/742 97/18722 0.00507184932376476 0.0465705123780631 ITGAV/ITGA6/NRP1/HSPA1A/PHIP/HSPA1B/TCF7L2/RB1CC1/GPX1/SIAH2 10 GO:0006941 striated muscle contraction 15/742 179/18722 0.00516493830942144 0.0472801143602632 AKAP9/GAA/ALDOA/CAV1/GJA1/DSP/DSG2/DSC2/GSTO1/GJA5/SLC9A1/DLG1/ATP1A1/CALM1/CALM2 15 GO:0030970 retrograde protein transport, ER to cytosol 5/742 29/18722 0.0051938321841398 0.0472801143602632 HSP90B1/OS9/FAF2/HM13/BCAP31 5 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 5/742 29/18722 0.0051938321841398 0.0472801143602632 P4HB/PPIA/HSPB1/GPX1/PARP1 5 GO:1903513 endoplasmic reticulum to cytosol transport 5/742 29/18722 0.0051938321841398 0.0472801143602632 HSP90B1/OS9/FAF2/HM13/BCAP31 5 GO:0006022 aminoglycan metabolic process 12/742 129/18722 0.00521885078314033 0.0472801143602632 ITIH5/CHPF/HEXA/NAGLU/FUCA1/B4GAT1/GUSB/GNS/B3GAT3/GLB1/CLTC/HEXB 12 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 6/742 41/18722 0.00522596077613606 0.0472801143602632 P4HB/NRP1/CALR/TRIOBP/S100A10/CDC42 6 GO:0001706 endoderm formation 7/742 54/18722 0.00523089028787542 0.0472801143602632 ITGAV/LAMB1/COL4A2/DUSP1/MMP15/ITGB5/RTF1 7 GO:0030520 intracellular estrogen receptor signaling pathway 7/742 54/18722 0.00523089028787542 0.0472801143602632 UFL1/ISL1/ARID1A/DDX17/DDX5/PARP1/LBH 7 GO:0006402 mRNA catabolic process 18/742 232/18722 0.00523526772369716 0.0472801143602632 FUS/ZFP36L1/NPM1/TNRC6A/HSPA1A/UPF2/TNRC6B/YBX1/HSPA1B/ROCK1/PUM1/DHX36/CELF1/LARP1/CIRBP/DDX5/HNRNPC/SSB 18 GO:0009988 cell-cell recognition 8/742 68/18722 0.00531481502623528 0.0478236543344304 ALDOA/SPESP1/FOLR1/CD81/DLG1/DOCK8/VDAC2/CCT3 8 GO:0032922 circadian regulation of gene expression 8/742 68/18722 0.00531481502623528 0.0478236543344304 MYCBP2/LGR4/EGR1/ZFHX3/MAGED1/KDM5A/HUWE1/ID1 8 GO:0010952 positive regulation of peptidase activity 16/742 197/18722 0.00533812780949023 0.0479460934161486 FBLN1/GRN/APP/CLDN4/CTSD/CAV1/ARL6IP5/ASPH/LGMN/NCSTN/S100A9/PMAIP1/PCOLCE2/BCAP31/RHOA/PSME2 16 GO:0010721 negative regulation of cell development 15/742 180/18722 0.0054348151002178 0.0487259284847113 FBN1/FBLN1/SEMA6A/KANK1/SEMA6D/RTN4/NRP1/BMP7/TACSTD2/NF1/ACTN4/PCM1/ID1/HES1/DYNLT1 15 GO:0050657 nucleic acid transport 14/742 163/18722 0.00546299729405196 0.0488014586484931 ZFP36L1/NPM1/TPR/PABPN1/UPF2/RANBP2/YBX1/HNRNPA1/SRSF7/THOC2/RAN/IGF2BP3/SSB/EIF5A 14 GO:0050658 RNA transport 14/742 163/18722 0.00546299729405196 0.0488014586484931 ZFP36L1/NPM1/TPR/PABPN1/UPF2/RANBP2/YBX1/HNRNPA1/SRSF7/THOC2/RAN/IGF2BP3/SSB/EIF5A 14 GO:0034599 cellular response to oxidative stress 21/742 288/18722 0.00551576442906003 0.0490137933051649 JUN/EGFR/FOS/P4HB/RHOB/MET/SOD3/BMP7/ARL6IP5/HSPA1A/ANXA1/HSPA1B/PPIA/FUT8/GPX8/TXN/EPAS1/HSPB1/GPX1/PARP1/DHRS2 21 GO:0031397 negative regulation of protein ubiquitination 9/742 83/18722 0.00551653220195783 0.0490137933051649 RPS20/UFL1/CAV1/SOX4/RPL23/HSPA1A/TRIM44/HSPA1B/PPIA 9 GO:0048678 response to axon injury 9/742 83/18722 0.00551653220195783 0.0490137933051649 LRP1/GRN/DAG1/PTPRF/JAM3/ISL1/FOLR1/MTR/NREP 9 GO:0007041 lysosomal transport 11/742 114/18722 0.00558344397993003 0.0495192338614979 LRP1/GRN/PSAP/RHOB/GCC2/HOOK2/HSPA1A/LAMP2/GNPTAB/LAMP1/CLN3 11 GO:0001666 response to hypoxia 22/742 307/18722 0.00559375678601003 0.049521789467544 MALAT1/HSP90B1/SLC2A1/LDHA/P4HB/CAV1/TGFBR3/SOD3/EGR1/ZFP36L1/SLC6A4/DPP4/BMP7/SLC9A1/ENO1/NF1/PMAIP1/HP1BP3/ADM/CITED2/EPAS1/RHOA 22 GO:0010951 negative regulation of endopeptidase activity 19/742 252/18722 0.00568742055980121 0.050260925877313 ITIH5/GAPDH/APLP2/SPINT1/APP/CRIM1/SPINT2/SERPINF1/DHCR24/SERPINH1/POR/ROCK1/CST3/TIMP3/GPX1/TFPI2/SIAH2/SERPINB9/SERPINB1 19 GO:0016049 cell growth 31/742 482/18722 0.00578545546687332 0.05063464522558 EGFR/NRP2/LRP1/APP/ITGB1/GOLGA4/SEMA6A/MACF1/IQGAP1/SEMA6D/GJA1/RTN4/NRP1/NPM1/HSPA1A/SLC9A1/ENO1/EIF4G1/S100A9/BTG1/AKAP13/KIAA1109/HSPA1B/USP9X/EIF2AK4/SMARCA2/YY1/CDC42/RHOA/RAB11A/SDCBP 31 GO:0043331 response to dsRNA 7/742 55/18722 0.0057936452992131 0.05063464522558 CAV1/SLC3A2/COLEC12/NPM1/PMAIP1/DHX36/NFKBIA 7 GO:0050810 regulation of steroid biosynthetic process 8/742 69/18722 0.00580845566429785 0.05063464522558 SF1/EGR1/POR/ATP1A1/MBTPS1/ADM/ASAH1/CGA 8 GO:1901224 positive regulation of NIK/NF-kappaB signaling 8/742 69/18722 0.00580845566429785 0.05063464522558 EGFR/APP/CALR/NFAT5/TRIM44/ACTN4/RHOA/PDCD4 8 GO:0022411 cellular component disassembly 29/742 443/18722 0.00587460800108579 0.05063464522558 LRP1/LAMC1/UFL1/RPL23/CTSV/DPP4/SPTAN1/IGF1R/MMP15/SPTBN1/VPS13C/KIF5B/ARID1A/TRIOBP/CST3/LAMP2/CFL1/RB1CC1/CALM1/HUWE1/VDAC1/TEX264/CLN3/DSTN/NEK6/CAPZB/HMGA1/EIF5A/UFC1 29 GO:0035461 vitamin transmembrane transport 4/742 19/18722 0.00589437370656702 0.05063464522558 LRP2/SLC19A1/FOLR1/SLC19A3 4 GO:0045780 positive regulation of bone resorption 4/742 19/18722 0.00589437370656702 0.05063464522558 EGFR/TFRC/ATP6AP1/LTBP3 4 GO:0045947 negative regulation of translational initiation 4/742 19/18722 0.00589437370656702 0.05063464522558 RPL13A/TPR/EIF2AK4/LARP1 4 GO:0060065 uterus development 4/742 19/18722 0.00589437370656702 0.05063464522558 ASH1L/NIPBL/KDM5B/GATA3 4 GO:0000723 telomere maintenance 12/742 131/18722 0.00589469793771334 0.05063464522558 ATRX/PRKDC/PPP1R10/HNRNPA1/DHX36/RIF1/RAD50/PARP1/HNRNPC/PTGES3/CCNE1/CCT3 12 GO:0019827 stem cell population maintenance 12/742 131/18722 0.00589469793771334 0.05063464522558 TPT1/ZC3H13/SOX4/LRP5/BMP7/NIPBL/NCOA3/RIF1/PCM1/RTF1/HES1/LBH 12 GO:0046683 response to organophosphorus 12/742 131/18722 0.00589469793771334 0.05063464522558 JUN/AKAP9/HSP90B1/FOS/HSPA5/APP/LDHA/FOSB/BSG/DUSP1/ZFP36L1/SLC6A4 12 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 12/742 131/18722 0.00589469793771334 0.05063464522558 LRP2/FBN2/FBN1/PEG10/HSPA5/LRP1/GLG1/CRIM1/CAV1/TGFBR3/LTBP1/HSPA1A 12 GO:0045214 sarcomere organization 6/742 42/18722 0.00589697146968322 0.05063464522558 KRT19/ITGB1/PLEC/KRT8/ACTG1/AKAP13 6 GO:0072595 maintenance of protein localization in organelle 6/742 42/18722 0.00589697146968322 0.05063464522558 HSPA5/GJA1/OS9/GPAA1/TXN/SKP1 6 GO:0034504 protein localization to nucleus 21/742 290/18722 0.00595898815756253 0.05063464522558 CDH1/TFRC/RPL23/PPP1R10/NPM1/BMP7/TPR/FERMT1/CALR/GLI3/MAGED1/RANBP2/TXN/NFKBIA/TRIM29/KPNB1/SKP1/PARP1/RAN/YWHAE/CCT3 21 GO:0071375 cellular response to peptide hormone stimulus 21/742 290/18722 0.00595898815756253 0.05063464522558 ATP2B1/FBN1/KANK1/CAV1/PRKDC/ZFP36L1/CSH1/IGF1R/POR/SRSF5/ESRRA/SLC9A1/PHIP/PTPRA/ROCK1/VAMP2/PKM/PARP1/LEPROT/CYP11A1/IGF2 21 GO:0042326 negative regulation of phosphorylation 26/742 385/18722 0.00596828149741868 0.05063464522558 FBLN1/LRP1/PLEC/GADD45B/DUSP1/CAV1/DUSP6/PRKDC/PLPP3/DYNLL1/LRP5/NPM1/BMP7/NR2F2/NF1/EIF4G1/ROCK1/NCOR1/GNAQ/CTDSPL/PPIA/CALM1/HSPB1/ADAR/CALM2/PDCD4 26 GO:0046825 regulation of protein export from nucleus 5/742 30/18722 0.00603301756407053 0.05063464522558 TPR/TCF7L2/PTPN14/TXN/YWHAE 5 GO:0140058 neuron projection arborization 5/742 30/18722 0.00603301756407053 0.05063464522558 LRP2/MACF1/NRP1/ROCK1/TPBG 5 GO:1902751 positive regulation of cell cycle G2/M phase transition 5/742 30/18722 0.00603301756407053 0.05063464522558 APP/PBX1/NPM1/BRD4/RAB11A 5 GO:2000637 positive regulation of gene silencing by miRNA 5/742 30/18722 0.00603301756407053 0.05063464522558 EGFR/EIF4G1/TNRC6B/PUM1/DDX5 5 GO:0002002 regulation of angiotensin levels in blood 3/742 10/18722 0.006037207699973 0.05063464522558 ENPEP/MME/ATP6AP2 3 GO:0002003 angiotensin maturation 3/742 10/18722 0.006037207699973 0.05063464522558 ENPEP/MME/ATP6AP2 3 GO:0030953 astral microtubule organization 3/742 10/18722 0.006037207699973 0.05063464522558 DLG1/KPNB1/RAB11A 3 GO:0036363 transforming growth factor beta activation 3/742 10/18722 0.006037207699973 0.05063464522558 ITGAV/LTBP1/LTBP3 3 GO:0050861 positive regulation of B cell receptor signaling pathway 3/742 10/18722 0.006037207699973 0.05063464522558 SLC39A10/CD81/FOXP1 3 GO:0098885 modification of postsynaptic actin cytoskeleton 3/742 10/18722 0.006037207699973 0.05063464522558 MYH10/PFN1/RHOA 3 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 3/742 10/18722 0.006037207699973 0.05063464522558 PMAIP1/SERINC3/DDIT3 3 GO:1904350 regulation of protein catabolic process in the vacuole 3/742 10/18722 0.006037207699973 0.05063464522558 LRP2/LRP1/CD81 3 GO:0046661 male sex differentiation 14/742 165/18722 0.00607424439068031 0.0506871069087175 LRP2/ADGRG1/SF1/ATRX/LGR4/DHCR24/CTSV/KDM5A/ARID5B/CITED2/GATA3/RHOBTB3/PRDX4/EIF2S2 14 GO:0071772 response to BMP 14/742 165/18722 0.00607424439068031 0.0506871069087175 LRP2/FBN1/SPINT1/CRIM1/SPINT2/TGFBR3/EGR1/BMP7/FSTL1/USP9X/GATA3/DDX5/HES1/PDCD4 14 GO:0071773 cellular response to BMP stimulus 14/742 165/18722 0.00607424439068031 0.0506871069087175 LRP2/FBN1/SPINT1/CRIM1/SPINT2/TGFBR3/EGR1/BMP7/FSTL1/USP9X/GATA3/DDX5/HES1/PDCD4 14 GO:0048738 cardiac muscle tissue development 18/742 236/18722 0.00622923465444933 0.0518927811011462 LRP2/ITGB1/PLEC/TGFBR3/GJA1/DSP/DSG2/BMP7/ISL1/CALR/GJA5/SLC9A1/AKAP13/CITED2/OBSL1/YY1/CDC42/CACYBP 18 GO:0007569 cell aging 12/742 132/18722 0.00625767971585502 0.0520419828220939 MIF/PRKDC/NPM1/CALR/MME/CDK6/YBX1/YPEL3/CITED2/NEK6/PDCD4/HMGA1 12 GO:0010959 regulation of metal ion transport 27/742 406/18722 0.00628224518464097 0.0521584726254225 AKAP9/AHNAK/ATP2B1/ITGB1/KCNN4/UTRN/CAV1/GJA1/ANK3/C4orf3/GSTO1/ATP2B4/PRSS8/SLC9A1/KIF5B/DLG1/STOM/DIAPH1/ACTN4/ATP1A1/VAMP2/CALM1/VDAC1/FXYD3/RHOA/CALM2/YWHAE 27 GO:0034249 negative regulation of cellular amide metabolic process 20/742 273/18722 0.00633071149414644 0.0524726758071869 GAPDH/RPL13A/ORMDL1/ZFP36L1/RTN4/TPR/TNRC6A/CALR/EIF4G1/TNRC6B/YBX1/ROCK1/PUM1/PURA/DHX36/EIF2AK4/CELF1/LARP1/CIRBP/IGF2BP3 20 GO:0035967 cellular response to topologically incorrect protein 11/742 116/18722 0.00635536184819462 0.0525218647564712 HSPA5/UFL1/PPP1R15A/HSPA1A/OS9/HSPA1B/DNAJB14/CREB3L2/ATF6/MBTPS1/DDIT3 11 GO:0009411 response to UV 13/742 149/18722 0.00639165694043986 0.0525218647564712 EGFR/RPL26/NPM1/MME/DDB1/TP53I13/SDF4/DHX36/EIF2AK4/CIRBP/GPX1/PARP1/YY1 13 GO:0051236 establishment of RNA localization 14/742 166/18722 0.00639977479787962 0.0525218647564712 ZFP36L1/NPM1/TPR/PABPN1/UPF2/RANBP2/YBX1/HNRNPA1/SRSF7/THOC2/RAN/IGF2BP3/SSB/EIF5A 14 GO:0001658 branching involved in ureteric bud morphogenesis 7/742 56/18722 0.00640043776991815 0.0525218647564712 LAMA5/LGR4/PBX1/TACSTD2/GLI3/MAGED1/DLG1 7 GO:0043388 positive regulation of DNA binding 7/742 56/18722 0.00640043776991815 0.0525218647564712 ISL1/TXN/CALM1/GATA3/PARP1/HES1/CALM2 7 GO:0071385 cellular response to glucocorticoid stimulus 7/742 56/18722 0.00640043776991815 0.0525218647564712 EGFR/ATP2B1/SERPINF1/ZFP36L1/ISL1/ANXA1/UBE2L3 7 GO:1903362 regulation of cellular protein catabolic process 19/742 255/18722 0.00643682030199717 0.0527200629108297 LRP2/LRP1/CTSC/UFL1/CAV1/RPL23/TMEM259/HSPA1A/CD81/HSPA1B/HECTD1/EIF3H/GNA12/GPX1/BCAP31/ATRAID/DDA1/PSME2/SDCBP 19 GO:0045069 regulation of viral genome replication 9/742 85/18722 0.00644593481743748 0.0527200629108297 HACD3/PKN2/MPHOSPH8/DDB1/PPIA/LARP1/DDX5/ADAR/BANF1 9 GO:0048638 regulation of developmental growth 23/742 330/18722 0.00650289898093215 0.0530691505087644 LRP1/APP/GOLGA4/SEMA6A/MACF1/TGFBR3/SEMA6D/GJA1/DUSP6/PRKDC/SLC6A4/RTN4/NRP1/LGMN/ADRB1/NIPBL/DUSP9/CELF1/CITED2/YY1/IGF2/RAB11A/CGA 23 GO:0097191 extrinsic apoptotic signaling pathway 17/742 219/18722 0.00651010226888891 0.0530691505087644 ITGAV/ITGA6/PDIA3/CAV1/KRT8/NRP1/HSPA1A/PHIP/PMAIP1/HSPA1B/TIMP3/TCF7L2/ERBB3/RB1CC1/KRT18/GPX1/SIAH2 17 GO:0006458 'de novo' protein folding 6/742 43/18722 0.00662864845789206 0.053857768720373 HSPA5/HSPA1A/HSPA1B/DNAJB14/DNAJB1/PTGES3 6 GO:0071604 transforming growth factor beta production 6/742 43/18722 0.00662864845789206 0.053857768720373 CD46/ITGAV/LTBP1/FERMT1/ATP6AP2/LTBP3 6 GO:0090596 sensory organ morphogenesis 19/742 256/18722 0.0067038112584785 0.0543790272855235 FBN2/FBN1/EFEMP1/TENM3/LRP5/NAGLU/BMP7/GLI3/NF1/FAT1/MAN2A1/NIPBL/TRIOBP/TUG1/ATP6V1B1/CITED2/GATA3/OBSL1/YY1 19 GO:0000281 mitotic cytokinesis 8/742 71/18722 0.00689953169530469 0.0558748960242708 SON/RHOB/MYH10/ANK3/SPTBN1/RASA1/ROCK1/RHOA 8 GO:0034103 regulation of tissue remodeling 9/742 86/18722 0.00695351115298366 0.0560225769050391 EGFR/TFRC/ATP6AP1/SUCO/NF1/LTBP3/ROCK1/CST3/SYT7 9 GO:0007369 gastrulation 15/742 185/18722 0.00696026646399975 0.0560225769050391 ITGB4/ITGAV/LAMB1/ITGB1/DAG1/RPS6/COL4A2/WLS/DUSP1/GJA1/LRP5/MMP15/BMP7/ITGB5/RTF1 15 GO:0060148 positive regulation of posttranscriptional gene silencing 5/742 31/18722 0.00696313000398664 0.0560225769050391 EGFR/EIF4G1/TNRC6B/PUM1/DDX5 5 GO:1900027 regulation of ruffle assembly 5/742 31/18722 0.00696313000398664 0.0560225769050391 KANK1/CAV1/TACSTD2/PFN1/EPS8L1 5 GO:0098727 maintenance of cell number 12/742 134/18722 0.0070365553114477 0.056472004987167 TPT1/ZC3H13/SOX4/LRP5/BMP7/NIPBL/NCOA3/RIF1/PCM1/RTF1/HES1/LBH 12 GO:0006611 protein export from nucleus 7/742 57/18722 0.00705328483341742 0.056472004987167 TPR/CALR/TCF7L2/PTPN14/TXN/RAN/YWHAE 7 GO:0033619 membrane protein proteolysis 7/742 57/18722 0.00705328483341742 0.056472004987167 DAG1/NCSTN/ROCK1/TIMP3/SPPL2B/MBTPS1/HM13 7 GO:0008406 gonad development 17/742 221/18722 0.00710837505307254 0.0565280448079767 LRP2/HSPA5/ADGRG1/SF1/ATRX/ADAMTS1/CTSV/NR2F2/KDM5A/ARID5B/CITED2/GATA3/RHOBTB3/PRDX4/EIF2S2/CYP19A1/CGA 17 GO:0000272 polysaccharide catabolic process 4/742 20/18722 0.00714038460732337 0.0565280448079767 GAA/AGL/RB1CC1/PYGL 4 GO:0003159 morphogenesis of an endothelium 4/742 20/18722 0.00714038460732337 0.0565280448079767 RHOB/FOXP1/RHOA/CSNK2B 4 GO:0007097 nuclear migration 4/742 20/18722 0.00714038460732337 0.0565280448079767 SYNE2/DYNC1H1/PCM1/CDC42 4 GO:0043555 regulation of translation in response to stress 4/742 20/18722 0.00714038460732337 0.0565280448079767 PPP1R15A/NPM1/EIF4G1/EIF2AK4 4 GO:0061154 endothelial tube morphogenesis 4/742 20/18722 0.00714038460732337 0.0565280448079767 RHOB/FOXP1/RHOA/CSNK2B 4 GO:0071243 cellular response to arsenic-containing substance 4/742 20/18722 0.00714038460732337 0.0565280448079767 SLC38A2/GSTO1/HNRNPA1/DHX36 4 GO:0006605 protein targeting 22/742 314/18722 0.00723009895879987 0.0571467021703542 HSPA5/TCAF1/LMAN1/SEC62/NACA/SIL1/ANK3/GCC2/VPS13C/OS9/STOM/NUCB1/LAMP2/SEC61A1/GNPTAB/SEC63/HUWE1/SPCS2/BCAP31/LEPROT/UBE2L3/SDCBP 22 GO:0030521 androgen receptor signaling pathway 6/742 44/18722 0.00742397539212941 0.058585364915526 ARID1A/DDX17/NCOR1/FOXP1/DDX5/RHOA 6 GO:0005977 glycogen metabolic process 8/742 72/18722 0.00749987068199292 0.0589957980398806 GAA/IL6ST/AGL/RB1CC1/PTGES3/IGF2/PYGL/UGP2 8 GO:0030330 DNA damage response, signal transduction by p53 class mediator 8/742 72/18722 0.00749987068199292 0.0589957980398806 ATRX/MIF/SOX4/RPL26/NPM1/PMAIP1/DDX5/USP10 8 GO:0098754 detoxification 13/742 152/18722 0.00752280694871767 0.0590821404239512 MGST3/SOD3/GSTO1/BMP7/GPX3/S100A9/GPX8/TXN/PRDX6/GPX1/PRDX4/GPX4/HBA2 13 GO:0033044 regulation of chromosome organization 15/742 187/18722 0.00765904187383464 0.0600566140583224 DUSP1/ATRX/PPP1R10/MPHOSPH8/TPR/HNRNPA1/DHX36/RAD50/PARP1/HNRNPC/NEK6/ANAPC11/UBE2C/LCMT1/CCT3 15 GO:0018208 peptidyl-proline modification 7/742 58/18722 0.00775420479724496 0.0605146472328438 P4HB/NKTR/P3H1/PPIG/RANBP2/PPIA/PRDX4 7 GO:2000649 regulation of sodium ion transmembrane transporter activity 7/742 58/18722 0.00775420479724496 0.0605146472328438 UTRN/ANK3/SLC9A1/KIF5B/STOM/ACTN4/FXYD3 7 GO:2000736 regulation of stem cell differentiation 7/742 58/18722 0.00775420479724496 0.0605146472328438 N4BP2L2/PRKDC/TACSTD2/LTBP3/DHX36/HES1/LBH 7 GO:0072073 kidney epithelium development 12/742 136/18722 0.00788977999455932 0.0611533385417436 LAMA5/IQGAP1/LGR4/PBX1/BMP7/TACSTD2/GLI3/MAGED1/DLG1/IRX2/GATA3/HES1 12 GO:0006026 aminoglycan catabolic process 5/742 32/18722 0.00798892851888659 0.0611533385417436 NAGLU/FUCA1/GUSB/GNS/GLB1 5 GO:0033687 osteoblast proliferation 5/742 32/18722 0.00798892851888659 0.0611533385417436 ITGAV/LRP5/JUNB/ATRAID/RHOA 5 GO:0035767 endothelial cell chemotaxis 5/742 32/18722 0.00798892851888659 0.0611533385417436 MET/NRP1/TMSB4X/LGMN/HSPB1 5 GO:0042744 hydrogen peroxide catabolic process 5/742 32/18722 0.00798892851888659 0.0611533385417436 GPX3/PRDX6/GPX1/PRDX4/HBA2 5 GO:0051497 negative regulation of stress fiber assembly 5/742 32/18722 0.00798892851888659 0.0611533385417436 MET/TACSTD2/PFN1/WASF2/PPP1R9A 5 GO:0051642 centrosome localization 5/742 32/18722 0.00798892851888659 0.0611533385417436 AKAP9/SYNE2/KIF5B/DLG1/RANBP2 5 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 5/742 32/18722 0.00798892851888659 0.0611533385417436 ERP29/HSPA1A/PMAIP1/SERINC3/DDIT3 5 GO:0006575 cellular modified amino acid metabolic process 15/742 188/18722 0.00802882773253783 0.0611533385417436 SLC19A1/GSTO1/POR/ARL6IP5/FOLR1/CROT/CLIC3/SERINC1/PCYOX1/SERINC3/CPQ/GATA3/GPX1/GPX4/CGA 15 GO:0007042 lysosomal lumen acidification 3/742 11/18722 0.0080588711317156 0.0611533385417436 GRN/ATP6AP2/CLN3 3 GO:0019372 lipoxygenase pathway 3/742 11/18722 0.0080588711317156 0.0611533385417436 GPX1/GPX4/HPGD 3 GO:0032329 serine transport 3/742 11/18722 0.0080588711317156 0.0611533385417436 SLC38A2/SLC1A5/SERINC3 3 GO:0036490 regulation of translation in response to endoplasmic reticulum stress 3/742 11/18722 0.0080588711317156 0.0611533385417436 PPP1R15A/EIF4G1/EIF2AK4 3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 3/742 11/18722 0.0080588711317156 0.0611533385417436 GSTO1/CALM1/CALM2 3 GO:0070417 cellular response to cold 3/742 11/18722 0.0080588711317156 0.0611533385417436 SLC9A1/EIF2AK4/NFKBIA 3 GO:0090084 negative regulation of inclusion body assembly 3/742 11/18722 0.0080588711317156 0.0611533385417436 HSPA1A/HSPA1B/DNAJB1 3 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction 3/742 11/18722 0.0080588711317156 0.0611533385417436 CAV1/CALM1/CALM2 3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 3/742 11/18722 0.0080588711317156 0.0611533385417436 HSPA5/ATF6/DDIT3 3 GO:0006073 cellular glucan metabolic process 8/742 73/18722 0.00813868980062065 0.061363066235211 GAA/IL6ST/AGL/RB1CC1/PTGES3/IGF2/PYGL/UGP2 8 GO:0044042 glucan metabolic process 8/742 73/18722 0.00813868980062065 0.061363066235211 GAA/IL6ST/AGL/RB1CC1/PTGES3/IGF2/PYGL/UGP2 8 GO:0007052 mitotic spindle organization 11/742 120/18722 0.00814861770248956 0.061363066235211 DYNC1H1/TACC2/TPR/HSPA1A/HSPA1B/KPNB1/CLTC/RAN/NEK6/RHOA/RAB11A 11 GO:0048593 camera-type eye morphogenesis 11/742 120/18722 0.00814861770248956 0.061363066235211 TENM3/LRP5/NAGLU/BMP7/GLI3/NF1/FAT1/MAN2A1/CITED2/OBSL1/YY1 11 GO:0048675 axon extension 11/742 120/18722 0.00814861770248956 0.061363066235211 NRP2/LRP1/ITGB1/GOLGA4/SEMA6A/MACF1/SEMA6D/RTN4/NRP1/USP9X/RAB11A 11 GO:0006892 post-Golgi vesicle-mediated transport 10/742 104/18722 0.00823529828259595 0.0617381517950904 GOLGA4/MACF1/ANK3/SPTBN1/VPS13C/VAMP2/SCAMP2/LAMP1/KRT18/CLN3 10 GO:0007265 Ras protein signal transduction 23/742 337/18722 0.00828486406692331 0.0617381517950904 JUN/ADGRG1/ITGB1/RHOB/MET/KANK1/DHCR24/HACD3/NRP1/NF1/AKAP13/WASF2/RASA1/ROCK1/CFL1/GNA12/ARHGAP5/KPNB1/CDC42/RHOA/EPS8L1/DYNLT1/SDCBP 23 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 6/742 45/18722 0.00828590984618318 0.0617381517950904 P4HB/ARL6IP5/PPIA/HSPB1/GPX1/PARP1 6 GO:0035987 endodermal cell differentiation 6/742 45/18722 0.00828590984618318 0.0617381517950904 ITGAV/LAMB1/COL4A2/MMP15/ITGB5/RTF1 6 GO:0048538 thymus development 6/742 45/18722 0.00828590984618318 0.0617381517950904 PBX1/PRKDC/LMO4/CITED2/GATA3/HES1 6 GO:0071364 cellular response to epidermal growth factor stimulus 6/742 45/18722 0.00828590984618318 0.0617381517950904 EGFR/EEF1A1/IQGAP1/ZFP36L1/PTPN12/ID1 6 GO:1904646 cellular response to amyloid-beta 6/742 45/18722 0.00828590984618318 0.0617381517950904 LRP1/APP/GJA1/IGF1R/LGMN/PARP1 6 GO:0016358 dendrite development 18/742 243/18722 0.0083350689793482 0.0620109047559941 APP/ITGB1/IQGAP1/DLG5/NRP1/BMP7/CUX1/KIDINS220/RERE/PPP1R9A/TPBG/CFL1/DHX36/OBSL1/ID1/CDC42/RHOA/DYNLT1 18 GO:0090303 positive regulation of wound healing 7/742 59/18722 0.00850521255160642 0.062841167088364 ITGB1/CLDN4/KANK1/PLPP3/FERMT1/ANXA1/ACTG1 7 GO:0032516 positive regulation of phosphoprotein phosphatase activity 4/742 21/18722 0.00854843406546166 0.062841167088364 SLC39A10/PPP1R15A/CALM1/CALM2 4 GO:0038083 peptidyl-tyrosine autophosphorylation 4/742 21/18722 0.00854843406546166 0.062841167088364 EGFR/CAV1/IQGAP1/IGF1R 4 GO:0045655 regulation of monocyte differentiation 4/742 21/18722 0.00854843406546166 0.062841167088364 JUN/ZFP36L1/CDK6/FOXP1 4 GO:0046885 regulation of hormone biosynthetic process 4/742 21/18722 0.00854843406546166 0.062841167088364 EGR1/POR/ATP1A1/ADM 4 GO:0150105 protein localization to cell-cell junction 4/742 21/18722 0.00854843406546166 0.062841167088364 DSP/LSR/DLG5/ACTG1 4 GO:1902307 positive regulation of sodium ion transmembrane transport 4/742 21/18722 0.00854843406546166 0.062841167088364 ANK3/SLC9A1/KIF5B/ACTN4 4 GO:2000178 negative regulation of neural precursor cell proliferation 4/742 21/18722 0.00854843406546166 0.062841167088364 SPINT1/SPINT2/SLC6A4/NF1 4 GO:1900407 regulation of cellular response to oxidative stress 9/742 89/18722 0.00866095692108255 0.0635737402528199 P4HB/MET/BMP7/PPIA/FUT8/TXN/HSPB1/GPX1/PARP1 9 GO:0051495 positive regulation of cytoskeleton organization 17/742 226/18722 0.00879966912335594 0.0644352312380666 AKAP9/IQGAP2/MET/DYNC1H1/CLIP1/NRP1/PFN1/HSPA1A/DLG1/WASF2/HSPA1B/ID1/S100A10/CDC42/ARPC3/DSTN/RHOA 17 GO:0010970 transport along microtubule 13/742 155/18722 0.00880653994931778 0.0644352312380666 ARMCX3/APP/DYNC1H1/DST/ARHGAP21/KIF5B/PURA/IFT27/LAMP1/PCM1/HSPB1/CLN3/CDC42 13 GO:0030968 endoplasmic reticulum unfolded protein response 8/742 74/18722 0.00881745269573543 0.0644352312380666 HSPA5/UFL1/PPP1R15A/OS9/CREB3L2/ATF6/MBTPS1/DDIT3 8 GO:1903532 positive regulation of secretion by cell 20/742 282/18722 0.00892279875367986 0.0651087530918442 EGFR/LRP1/KCNN4/WLS/MYH10/SOX4/GJA1/SLC6A4/DYNLL1/ATP6AP1/ISL1/FRMD4A/KIF5B/TCF7L2/SYT7/PPIA/LAMP1/PHPT1/CYP19A1/SDCBP 20 GO:0017148 negative regulation of translation 18/742 245/18722 0.00903184170547526 0.0658072242257342 GAPDH/RPL13A/ZFP36L1/TPR/TNRC6A/CALR/EIF4G1/TNRC6B/YBX1/ROCK1/PUM1/PURA/DHX36/EIF2AK4/CELF1/LARP1/CIRBP/IGF2BP3 18 GO:0000910 cytokinesis 14/742 173/18722 0.00908792562994627 0.0658308511146313 SON/RHOB/PLEC/MYH10/PKN2/ANK3/SPTBN1/RASA1/ROCK1/CALM1/CDC42/RHOA/RAB11A/CALM2 14 GO:0031116 positive regulation of microtubule polymerization 5/742 33/18722 0.00911504092356433 0.0658308511146313 AKAP9/MET/CLIP1/HSPA1A/HSPA1B 5 GO:0046685 response to arsenic-containing substance 5/742 33/18722 0.00911504092356433 0.0658308511146313 SERPINF1/SLC38A2/GSTO1/HNRNPA1/DHX36 5 GO:0048048 embryonic eye morphogenesis 5/742 33/18722 0.00911504092356433 0.0658308511146313 FBN2/FBN1/EFEMP1/BMP7/CITED2 5 GO:0061842 microtubule organizing center localization 5/742 33/18722 0.00911504092356433 0.0658308511146313 AKAP9/SYNE2/KIF5B/DLG1/RANBP2 5 GO:0071353 cellular response to interleukin-4 5/742 33/18722 0.00911504092356433 0.0658308511146313 HSPA5/RPLP0/RPL3/GATA3/TUBA1B 5 GO:0045137 development of primary sexual characteristics 17/742 227/18722 0.00917369725988537 0.0659910566559255 LRP2/HSPA5/ADGRG1/SF1/ATRX/ADAMTS1/CTSV/NR2F2/KDM5A/ARID5B/CITED2/GATA3/RHOBTB3/PRDX4/EIF2S2/CYP19A1/CGA 17 GO:0050878 regulation of body fluid levels 25/742 379/18722 0.00919138691025365 0.0659910566559255 F5/EGFR/FBLN1/LMAN1/CLDN4/MET/KCNN4/PLEC/CAV1/IL6ST/GJA1/ANXA5/LSR/PRLR/GJA5/ACTG1/GNAQ/PPIA/ADM/GNA12/ATP6V1B1/HSPB1/TFPI2/TLN1/MYL12A 25 GO:0051346 negative regulation of hydrolase activity 25/742 379/18722 0.00919138691025365 0.0659910566559255 ITIH5/GAPDH/APLP2/SPINT1/LRP1/APP/CRIM1/SPINT2/SERPINF1/BOD1L1/DHCR24/SERPINH1/PPP1R15A/POR/ANXA1/KDM5A/ROCK1/CST3/TIMP3/GPX1/TFPI2/SIAH2/SERPINB9/SERPINB1/CNN3 25 GO:0006984 ER-nucleus signaling pathway 6/742 46/18722 0.00921737431024061 0.0659910566559255 HSPA5/PPP1R15A/CCDC47/ATF6/MBTPS1/DDIT3 6 GO:0050919 negative chemotaxis 6/742 46/18722 0.00921737431024061 0.0659910566559255 NRP2/ITGAV/SEMA6A/SEMA6D/DPP4/RHOA 6 GO:1900271 regulation of long-term synaptic potentiation 6/742 46/18722 0.00921737431024061 0.0659910566559255 APP/MME/LGMN/NCSTN/PPP1R9A/EIF2AK4 6 GO:0044262 cellular carbohydrate metabolic process 20/742 283/18722 0.00925720532654301 0.0661803101492366 GAA/IL6ST/AGL/TPI1/DDB1/GUSB/PMAIP1/RANBP2/GLB1/SLC5A3/ISYNA1/NCOR1/GNPTAB/RB1CC1/SLC35B4/PTGES3/IGF2/PYGL/UGP2/LCMT1 20 GO:0006893 Golgi to plasma membrane transport 7/742 60/18722 0.00930831500150613 0.0664495319471681 GOLGA4/MACF1/ANK3/SPTBN1/VAMP2/KRT18/CLN3 7 GO:0001659 temperature homeostasis 14/742 174/18722 0.00953544178676487 0.0679727019143124 DYNC1H1/CAV1/LGR4/GJA1/EGR1/IGF1R/PRLR/ADRB1/ACADVL/DDIT3/EPAS1/GPX1/ID1/GADD45G 14 GO:0036293 response to decreased oxygen levels 22/742 322/18722 0.00955966994279187 0.0680472183247721 MALAT1/HSP90B1/SLC2A1/LDHA/P4HB/CAV1/TGFBR3/SOD3/EGR1/ZFP36L1/SLC6A4/DPP4/BMP7/SLC9A1/ENO1/NF1/PMAIP1/HP1BP3/ADM/CITED2/EPAS1/RHOA 22 GO:0022409 positive regulation of cell-cell adhesion 20/742 284/18722 0.00960164259351641 0.0682476466359296 CD46/TFRC/CAV1/SOX4/IL6ST/PLPP3/DPP4/ANK3/BMP7/NFAT5/CD81/ANXA1/GLI3/CD55/CITED2/GATA3/DOCK8/HES1/RHOA/IGF2 20 GO:0001837 epithelial to mesenchymal transition 13/742 157/18722 0.00975370069158252 0.0691295285744873 DAG1/TGFBR3/DLG5/RTN4/BMP7/ISL1/ROCK1/DDX17/TCF7L2/GATA3/DDX5/PDCD4/SDCBP 13 GO:0007034 vacuolar transport 13/742 157/18722 0.00975370069158252 0.0691295285744873 LRP1/GRN/PSAP/RHOB/GCC2/HOOK2/HSPA1A/VPS13C/LAMP2/GNPTAB/LAMP1/CLN3/LEPROT 13 GO:0001933 negative regulation of protein phosphorylation 23/742 342/18722 0.00978707147310739 0.0692666662996426 FBLN1/LRP1/PLEC/GADD45B/DUSP1/CAV1/DUSP6/PRKDC/PLPP3/LRP5/NPM1/BMP7/NR2F2/NF1/EIF4G1/GNAQ/CTDSPL/PPIA/CALM1/HSPB1/ADAR/CALM2/PDCD4 23 GO:0010927 cellular component assembly involved in morphogenesis 10/742 107/18722 0.00998211659144613 0.0705460028065005 ITGB4/KRT19/ITGB1/DAG1/PLEC/KRT8/ACTG1/GPC1/AKAP13/OBSL1 10 GO:0002320 lymphoid progenitor cell differentiation 4/742 22/18722 0.0101263313874923 0.0710291404538465 SOX4/PRKDC/GATA3/HES1 4 GO:0051412 response to corticosterone 4/742 22/18722 0.0101263313874923 0.0710291404538465 ATP2B1/FOS/FOSB/CALM1 4 GO:0140467 integrated stress response signaling 4/742 22/18722 0.0101263313874923 0.0710291404538465 HSPA5/PPP1R15A/DDIT3/EIF2AK4 4 GO:2000114 regulation of establishment of cell polarity 4/742 22/18722 0.0101263313874923 0.0710291404538465 KANK1/ROCK1/GATA3/DOCK8 4 GO:0034113 heterotypic cell-cell adhesion 7/742 61/18722 0.0101655065386375 0.0710291404538465 ITGAV/ITGB1/DSP/DSG2/DSC2/BMP7/JAM3 7 GO:0042255 ribosome assembly 7/742 61/18722 0.0101655065386375 0.0710291404538465 RPLP0/RPL23A/RPL6/RPL24/PRKDC/NPM1/RPL3 7 GO:0071384 cellular response to corticosteroid stimulus 7/742 61/18722 0.0101655065386375 0.0710291404538465 EGFR/ATP2B1/SERPINF1/ZFP36L1/ISL1/ANXA1/UBE2L3 7 GO:0090342 regulation of cell aging 7/742 61/18722 0.0101655065386375 0.0710291404538465 MIF/PRKDC/CDK6/YBX1/YPEL3/NEK6/HMGA1 7 GO:0048483 autonomic nervous system development 6/742 47/18722 0.0102212474620603 0.0712171543900955 NRP2/SOX4/NRP1/NF1/GATA3/HES1 6 GO:1903170 negative regulation of calcium ion transmembrane transport 6/742 47/18722 0.0102212474620603 0.0712171543900955 C4orf3/GSTO1/CALM1/VDAC1/CALM2/YWHAE 6 GO:0043488 regulation of mRNA stability 13/742 158/18722 0.0102561865560008 0.0713599458966818 FUS/ZFP36L1/NPM1/TNRC6A/TNRC6B/YBX1/ROCK1/PUM1/DHX36/CELF1/LARP1/CIRBP/HNRNPC 13 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 5/742 34/18722 0.0103459457086575 0.0715765028516738 MIF/RPL26/NPM1/PMAIP1/DDX5 5 GO:0008584 male gonad development 12/742 141/18722 0.0103787221665435 0.0715765028516738 LRP2/ADGRG1/SF1/ATRX/CTSV/KDM5A/ARID5B/CITED2/GATA3/RHOBTB3/PRDX4/EIF2S2 12 GO:0035296 regulation of tube diameter 12/742 141/18722 0.0103787221665435 0.0715765028516738 EGFR/ATP2B1/CAV1/GJA1/SOD3/SLC6A4/GJA5/ADRB1/ROCK1/ADM/GPX1/RHOA 12 GO:0097746 blood vessel diameter maintenance 12/742 141/18722 0.0103787221665435 0.0715765028516738 EGFR/ATP2B1/CAV1/GJA1/SOD3/SLC6A4/GJA5/ADRB1/ROCK1/ADM/GPX1/RHOA 12 GO:0002328 pro-B cell differentiation 3/742 12/18722 0.0104322028447784 0.0715765028516738 SOX4/PRKDC/HES1 3 GO:0009886 post-embryonic animal morphogenesis 3/742 12/18722 0.0104322028447784 0.0715765028516738 FBN1/EFEMP1/ATRX 3 GO:0048548 regulation of pinocytosis 3/742 12/18722 0.0104322028447784 0.0715765028516738 CAV1/CLN3/CDC42 3 GO:0060019 radial glial cell differentiation 3/742 12/18722 0.0104322028447784 0.0715765028516738 GLI3/HES1/RHOA 3 GO:0070493 thrombin-activated receptor signaling pathway 3/742 12/18722 0.0104322028447784 0.0715765028516738 IQGAP2/MET/HPGD 3 GO:0098974 postsynaptic actin cytoskeleton organization 3/742 12/18722 0.0104322028447784 0.0715765028516738 ACTG1/WASF2/PPP1R9A 3 GO:1901654 response to ketone 15/742 194/18722 0.0105561468681478 0.0723264431742722 EGFR/ATP2B1/FOS/CLDN4/SERPINF1/FOSB/DUSP1/CAV1/TGFBR3/CALR/GLB1/LARP1/CALM1/PARP1/CSNK2B 15 GO:0035150 regulation of tube size 12/742 142/18722 0.0109422661635184 0.0747645848517025 EGFR/ATP2B1/CAV1/GJA1/SOD3/SLC6A4/GJA5/ADRB1/ROCK1/ADM/GPX1/RHOA 12 GO:0046546 development of primary male sexual characteristics 12/742 142/18722 0.0109422661635184 0.0747645848517025 LRP2/ADGRG1/SF1/ATRX/CTSV/KDM5A/ARID5B/CITED2/GATA3/RHOBTB3/PRDX4/EIF2S2 12 GO:0030324 lung development 14/742 177/18722 0.0109826386381076 0.0749367884975853 EGFR/LAMA5/DAG1/DLG5/MME/GLI3/LTBP3/MAN2A1/MAN1A2/SRSF6/EPAS1/HES1/PTGES3/CDC42 14 GO:0060135 maternal process involved in female pregnancy 7/742 62/18722 0.011078764568434 0.0754884096111225 BSG/GJA1/CTSV/NR2F2/ASH1L/JUNB/CITED2 7 GO:0000380 alternative mRNA splicing, via spliceosome 8/742 77/18722 0.0111080277090079 0.07558354942493 RBM25/TRA2B/HNRNPA1/DDX17/SRSF6/CELF1/DDX5/MBNL3 8 GO:0032414 positive regulation of ion transmembrane transporter activity 10/742 109/18722 0.0112945757400992 0.0765802980967258 AKAP9/TCAF1/ANK3/GSTO1/TMSB4X/SLC9A1/KIF5B/ACTN4/CALM1/CALM2 10 GO:0034766 negative regulation of ion transmembrane transport 10/742 109/18722 0.0112945757400992 0.0765802980967258 CAV1/SLC43A2/ANK3/C4orf3/GSTO1/ARL6IP5/CALM1/VDAC1/CALM2/YWHAE 10 GO:0007517 muscle organ development 22/742 327/18722 0.0113010196988893 0.0765802980967258 LRP2/FOS/LAMA5/DAG1/PLEC/UTRN/CAV1/TGFBR3/DSP/EGR1/ZFHX3/ISL1/NR2F2/GPC1/DDX17/CHD2/ARID5B/CITED2/DDX5/GPX1/RHOA/IGF2 22 GO:0060349 bone morphogenesis 9/742 93/18722 0.0114101503543996 0.0772138941790879 GLG1/TRIP11/SERPINH1/LRP5/POR/GLI3/LTBP3/TMEM107/CITED2 9 GO:0000082 G1/S transition of mitotic cell cycle 16/742 214/18722 0.0114280074246008 0.0772289421033215 EGFR/ITGB1/RPS6/SOX4/RPL26/ADAMTS1/PRKDC/BRD4/ANXA1/CDK6/EIF4G1/DLG1/CTDSPL/BRD7/PSME2/CCNE1 16 GO:0050808 synapse organization 27/742 426/18722 0.0114681584035134 0.0773944023406509 NRP2/CDH1/APP/DAG1/MYH10/ANK3/DLG5/IGF1R/NRP1/PTPRF/PFN1/ACTG1/LGMN/EIF4G1/DLG1/WASF2/PPP1R9A/TPBG/ERC1/CFL1/SDF4/DHX36/OBSL1/CLN3/CDC42/RHOA/SDCBP 27 GO:0070482 response to oxygen levels 23/742 347/18722 0.01150277117208 0.0774883026675187 MALAT1/HSP90B1/SLC2A1/LDHA/P4HB/CAV1/TGFBR3/SOD3/EGR1/ZFP36L1/SLC6A4/DPP4/ATP6AP1/BMP7/SLC9A1/ENO1/NF1/PMAIP1/HP1BP3/ADM/CITED2/EPAS1/RHOA 23 GO:0045664 regulation of neuron differentiation 15/742 196/18722 0.0115251150017499 0.0774883026675187 APP/PBX1/SLC6A4/ZFHX3/BMP7/ISL1/CALR/GLI3/EIF4G1/ROCK1/TUG1/EIF2AK4/HES1/NREP/RHOA 15 GO:0006865 amino acid transport 12/742 143/18722 0.0115291300527584 0.0774883026675187 ITGB1/SLC3A2/SLC38A1/SLC43A2/SLC38A2/GJA1/SLC1A5/SLC38A10/ARL6IP5/SLC38A9/SERINC3/CLN3 12 GO:0010765 positive regulation of sodium ion transport 5/742 35/18722 0.0116859554138249 0.077906369425499 ANK3/PRSS8/SLC9A1/KIF5B/ACTN4 5 GO:0032232 negative regulation of actin filament bundle assembly 5/742 35/18722 0.0116859554138249 0.077906369425499 MET/TACSTD2/PFN1/WASF2/PPP1R9A 5 GO:0045454 cell redox homeostasis 5/742 35/18722 0.0116859554138249 0.077906369425499 DDIT3/TXN/PRDX6/GPX1/PRDX4 5 GO:0045907 positive regulation of vasoconstriction 5/742 35/18722 0.0116859554138249 0.077906369425499 EGFR/CAV1/GJA1/GJA5/RHOA 5 GO:0060236 regulation of mitotic spindle organization 5/742 35/18722 0.0116859554138249 0.077906369425499 DYNC1H1/TPR/HSPA1A/HSPA1B/CLTC 5 GO:0086005 ventricular cardiac muscle cell action potential 5/742 35/18722 0.0116859554138249 0.077906369425499 CAV1/DSP/DSG2/DSC2/DLG1 5 GO:0033674 positive regulation of kinase activity 29/742 467/18722 0.0117168807050687 0.0780072650714815 EGFR/DAG1/MET/ERP29/IQGAP1/EPHB4/EGR1/FLT1/IGF1R/NPM1/ATP2B4/LMO4/PRLR/CD81/MAGED1/DLG1/AKAP13/RANBP2/PPP1R9A/PPIA/ERBB3/RAD50/TXN/CALM1/CDC42/RHOA/IGF2/CALM2/CKS1B 29 GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 4/742 23/18722 0.0118812658579761 0.0785722266913012 ENPEP/MME/ATP6AP2/RHOA 4 GO:0021871 forebrain regionalization 4/742 23/18722 0.0118812658579761 0.0785722266913012 ADGRG1/GLI3/TRA2B/PGAP1 4 GO:0030325 adrenal gland development 4/742 23/18722 0.0118812658579761 0.0785722266913012 PBX1/NF1/ARID5B/CITED2 4 GO:1900273 positive regulation of long-term synaptic potentiation 4/742 23/18722 0.0118812658579761 0.0785722266913012 APP/MME/LGMN/EIF2AK4 4 GO:1904666 regulation of ubiquitin protein ligase activity 4/742 23/18722 0.0118812658579761 0.0785722266913012 RPS20/RPL23/SKP1/UBE2C 4 GO:0032024 positive regulation of insulin secretion 8/742 78/18722 0.0119611672267882 0.0787842214671114 LRP1/SOX4/GJA1/DYNLL1/ISL1/KIF5B/TCF7L2/PHPT1 8 GO:0043297 apical junction assembly 8/742 78/18722 0.0119611672267882 0.0787842214671114 CLDN4/GJA1/PKN2/DLG5/DLG1/ROCK1/MARVELD3/RHOA 8 GO:0070373 negative regulation of ERK1 and ERK2 cascade 8/742 78/18722 0.0119611672267882 0.0787842214671114 FBLN1/SEMA6A/EIF3A/DUSP1/DUSP6/DLG1/DUSP9/TIMP3 8 GO:0007088 regulation of mitotic nuclear division 10/742 110/18722 0.0119978437056154 0.0789205697812782 DUSP1/LRP5/BMP7/TPR/PHIP/OBSL1/CDC42/IGF2/ANAPC11/LCMT1 10 GO:0030239 myofibril assembly 7/742 63/18722 0.0120500451068414 0.0791585409944103 KRT19/ITGB1/PLEC/KRT8/ACTG1/AKAP13/OBSL1 7 GO:0009612 response to mechanical stimulus 16/742 216/18722 0.0124074005267468 0.0813807840026613 JUN/EGFR/FOS/SLC2A1/DAG1/JUND/PLEC/FOSB/SLC38A2/GJA1/TMEM150C/SLC9A1/ATP1A1/NFKBIA/CITED2/RHOA 16 GO:0006376 mRNA splice site selection 6/742 49/18722 0.0124574652829921 0.0813807840026613 SF1/SRSF5/LUC7L3/SRSF6/CELF1/SNRPC 6 GO:0034332 adherens junction organization 6/742 49/18722 0.0124574652829921 0.0813807840026613 CDH1/PLEC/DSP/DLG5/JAM3/CDC42 6 GO:0034250 positive regulation of cellular amide metabolic process 13/742 162/18722 0.0124706990870475 0.0813807840026613 SOX4/RPL26/PRKDC/PPP1R15A/NPM1/EIF4G1/DHX36/EIF2AK4/LARP1/CIRBP/PKM/RHOA/EIF5A 13 GO:0051494 negative regulation of cytoskeleton organization 13/742 162/18722 0.0124706990870475 0.0813807840026613 MET/KANK1/SPTAN1/NPM1/TACSTD2/PFN1/TMSB4X/SPTBN1/WASF2/TRIOBP/PPP1R9A/KANK4/CAPZB 13 GO:0046942 carboxylic acid transport 19/742 273/18722 0.0127940937471112 0.0833810331276115 LRP2/SLC26A2/ITGB1/PSAP/SLC3A2/SLC38A1/SLC43A2/SLC38A2/GJA1/SLC1A5/SLC19A1/ARL6IP5/SLC38A9/FOLR1/ANXA1/SLC16A12/SERINC3/SLC16A1/CLN3 19 GO:0034765 regulation of ion transmembrane transport 30/742 491/18722 0.0129209715295725 0.0839657190508755 AKAP9/AHNAK/TCAF1/APP/ITGB1/KCNN4/UTRN/CAV1/SLC43A2/ANK3/C4orf3/GSTO1/ATP2B4/ARL6IP5/GJA5/TMSB4X/CLIC3/SLC9A1/KIF5B/DLG1/STOM/DIAPH1/ACTN4/TMEM109/VAMP2/CALM1/VDAC1/FXYD3/CALM2/YWHAE 30 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 9/742 95/18722 0.0130074060425723 0.0839657190508755 RPS20/UFL1/CAV1/SOX4/RPL23/HSPA1A/TRIM44/HSPA1B/PPIA 9 GO:0048857 neural nucleus development 7/742 64/18722 0.0130812784605178 0.0839657190508755 HSPA5/DYNLL1/CALM1/CDC42/RHOA/CALM2/YWHAE 7 GO:0055002 striated muscle cell development 7/742 64/18722 0.0130812784605178 0.0839657190508755 KRT19/ITGB1/PLEC/KRT8/ACTG1/AKAP13/OBSL1 7 GO:0051385 response to mineralocorticoid 5/742 36/18722 0.0131392014987716 0.0839657190508755 ATP2B1/FOS/FOSB/CALM1/PARP1 5 GO:0070670 response to interleukin-4 5/742 36/18722 0.0131392014987716 0.0839657190508755 HSPA5/RPLP0/RPL3/GATA3/TUBA1B 5 GO:0006983 ER overload response 3/742 13/18722 0.0131677118270629 0.0839657190508755 HSPA5/CCDC47/DDIT3 3 GO:0010958 regulation of amino acid import across plasma membrane 3/742 13/18722 0.0131677118270629 0.0839657190508755 ITGB1/SLC43A2/ARL6IP5 3 GO:0032429 regulation of phospholipase A2 activity 3/742 13/18722 0.0131677118270629 0.0839657190508755 EGFR/LRP1/ANXA1 3 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 3/742 13/18722 0.0131677118270629 0.0839657190508755 GSTO1/CALM1/CALM2 3 GO:0051481 negative regulation of cytosolic calcium ion concentration 3/742 13/18722 0.0131677118270629 0.0839657190508755 ATP2B1/LRP1/GTF2I 3 GO:0098814 spontaneous synaptic transmission 3/742 13/18722 0.0131677118270629 0.0839657190508755 APP/ITGB1/PPP1R9A 3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding 3/742 13/18722 0.0131677118270629 0.0839657190508755 TMSB4X/NSD1/DDIT3 3 GO:1903789 regulation of amino acid transmembrane transport 3/742 13/18722 0.0131677118270629 0.0839657190508755 ITGB1/SLC43A2/ARL6IP5 3 GO:1905244 regulation of modification of synaptic structure 3/742 13/18722 0.0131677118270629 0.0839657190508755 CLN3/CDC42/RHOA 3 GO:0008361 regulation of cell size 14/742 181/18722 0.0131727595676981 0.0839657190508755 LRP1/GOLGA4/SEMA6A/KCNN4/MACF1/SLC12A9/SEMA6D/RTN4/NRP1/NPM1/RB1CC1/CLN3/RHOA/RAB11A 14 GO:0030323 respiratory tube development 14/742 181/18722 0.0131727595676981 0.0839657190508755 EGFR/LAMA5/DAG1/DLG5/MME/GLI3/LTBP3/MAN2A1/MAN1A2/SRSF6/EPAS1/HES1/PTGES3/CDC42 14 GO:0048813 dendrite morphogenesis 12/742 146/18722 0.0134356970000827 0.085521262742678 ITGB1/NRP1/CUX1/KIDINS220/RERE/PPP1R9A/TPBG/CFL1/DHX36/OBSL1/ID1/CDC42 12 GO:0042445 hormone metabolic process 16/742 218/18722 0.0134514212856398 0.085521262742678 CTSL/ENPEP/EGR1/POR/MME/ATP6AP2/ATP1A1/TCF7L2/ADM/CPQ/GATA3/DHRS2/CYP11A1/HSD17B1/CYP19A1/CGA 16 GO:0050680 negative regulation of epithelial cell proliferation 13/742 164/18722 0.0137078803427305 0.0863081607446283 SERPINF1/CAV1/TGFBR3/GJA1/FLT1/ISL1/NR2F2/CDK6/NF1/MAGED1/DLG1/GATA3/MARVELD3 13 GO:0050792 regulation of viral process 13/742 164/18722 0.0137078803427305 0.0863081607446283 P4HB/HACD3/PKN2/MPHOSPH8/DDB1/STOM/PPIA/RSF1/LARP1/DDX5/ADAR/DYNLT1/BANF1 13 GO:0001570 vasculogenesis 8/742 80/18722 0.0138105130448151 0.0863081607446283 ITGAV/CAV1/TGFBR3/ZFP36L1/JUNB/RASA1/ADM/CITED2 8 GO:0009791 post-embryonic development 8/742 80/18722 0.0138105130448151 0.0863081607446283 FBN1/EFEMP1/ATRX/CCDC47/ASH1L/ARID5B/KDM5B/GATA3 8 GO:0032204 regulation of telomere maintenance 8/742 80/18722 0.0138105130448151 0.0863081607446283 ATRX/PPP1R10/HNRNPA1/DHX36/RAD50/PARP1/HNRNPC/CCT3 8 GO:0003148 outflow tract septum morphogenesis 4/742 24/18722 0.0138197884917006 0.0863081607446283 LRP2/NRP2/NRP1/ISL1 4 GO:0016486 peptide hormone processing 4/742 24/18722 0.0138197884917006 0.0863081607446283 CTSL/ENPEP/MME/ATP6AP2 4 GO:0021801 cerebral cortex radial glia-guided migration 4/742 24/18722 0.0138197884917006 0.0863081607446283 ADGRG1/LAMB1/RTN4/GLI3 4 GO:0022030 telencephalon glial cell migration 4/742 24/18722 0.0138197884917006 0.0863081607446283 ADGRG1/LAMB1/RTN4/GLI3 4 GO:0030859 polarized epithelial cell differentiation 4/742 24/18722 0.0138197884917006 0.0863081607446283 DLG5/FAT1/CDC42/RHOA 4 GO:0051647 nucleus localization 4/742 24/18722 0.0138197884917006 0.0863081607446283 SYNE2/DYNC1H1/PCM1/CDC42 4 GO:0060149 negative regulation of posttranscriptional gene silencing 4/742 24/18722 0.0138197884917006 0.0863081607446283 NEAT1/KCNQ1OT1/NCOR1/ADAR 4 GO:0060967 negative regulation of gene silencing by RNA 4/742 24/18722 0.0138197884917006 0.0863081607446283 NEAT1/KCNQ1OT1/NCOR1/ADAR 4 GO:2001026 regulation of endothelial cell chemotaxis 4/742 24/18722 0.0138197884917006 0.0863081607446283 MET/TMSB4X/LGMN/HSPB1 4 GO:0003073 regulation of systemic arterial blood pressure 9/742 96/18722 0.0138655921364483 0.0864848802450185 ENPEP/GJA1/NR2F2/GJA5/MME/ATP6AP2/ADRB1/ADM/RHOA 9 GO:0046879 hormone secretion 20/742 295/18722 0.0141136625799567 0.0878561645122125 EGFR/LRP1/SOX4/GJA1/DPP4/DYNLL1/LRP5/ISL1/ANXA1/KIF5B/TCF7L2/SYT7/ADM/KDM5B/SLC16A1/GATA3/HMGN3/PHPT1/CYP19A1/CGA 20 GO:0006487 protein N-linked glycosylation 7/742 65/18722 0.0141743650032861 0.0878561645122125 RPN2/DDOST/MOGS/TUSC3/TMEM165/FUT8/RPN1 7 GO:0048645 animal organ formation 7/742 65/18722 0.0141743650032861 0.0878561645122125 LRP2/BMP7/ISL1/FOLR1/GLI3/CITED2/HES1 7 GO:1902475 L-alpha-amino acid transmembrane transport 7/742 65/18722 0.0141743650032861 0.0878561645122125 ITGB1/SLC3A2/SLC38A1/SLC43A2/SLC1A5/ARL6IP5/SLC38A9 7 GO:1905330 regulation of morphogenesis of an epithelium 7/742 65/18722 0.0141743650032861 0.0878561645122125 LGR4/GJA1/BMP7/TACSTD2/MAGED1/FOXP1/GATA3 7 GO:0005996 monosaccharide metabolic process 18/742 257/18722 0.0142510665835239 0.0881239529640163 GAPDH/SLC2A1/GAA/ALDOA/LRP5/FUCA1/GSTO1/TPI1/ENO1/DDB1/PMAIP1/MAN2A1/RANBP2/GLB1/FUT8/SLC35B4/IGF2/LCMT1 18 GO:0051054 positive regulation of DNA metabolic process 15/742 201/18722 0.0142532466433702 0.0881239529640163 EGFR/FUS/TFRC/ATRX/PRKDC/PPP1R10/HNRNPA1/USP9X/DHX36/RIF1/RAD50/PARP1/PTGES3/ANXA3/CCT3 15 GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 11/742 130/18722 0.0143509933867143 0.0885669663955433 LMAN1/TMED9/TRIP11/MIA3/TMED4/PGAP1/CREB3L2/LMAN2/ERGIC2/TMED1/BCAP31 11 GO:0050796 regulation of insulin secretion 13/742 165/18722 0.0143607571017875 0.0885669663955433 LRP1/SOX4/GJA1/DPP4/DYNLL1/LRP5/ISL1/KIF5B/TCF7L2/SYT7/SLC16A1/HMGN3/PHPT1 13 GO:0031503 protein-containing complex localization 16/742 220/18722 0.0145628023518937 0.0895893444811392 AKAP9/DAG1/NPM1/TPR/PABPN1/KIF5B/UPF2/DLG1/VAMP2/PURA/THOC2/IFT27/PCM1/RAN/RAB11A/SSB 16 GO:0048705 skeletal system morphogenesis 16/742 220/18722 0.0145628023518937 0.0895893444811392 FBN2/GLG1/ANKRD11/TRIP11/SERPINH1/LRP5/BMP7/POR/GLI3/LTBP3/DLG1/NIPBL/SLC39A1/ARID5B/TMEM107/CITED2 16 GO:0003161 cardiac conduction system development 5/742 37/18722 0.0147096207017069 0.0902480369900685 GJA1/DSG2/ISL1/GJA5/CDC42 5 GO:0031112 positive regulation of microtubule polymerization or depolymerization 5/742 37/18722 0.0147096207017069 0.0902480369900685 AKAP9/MET/CLIP1/HSPA1A/HSPA1B 5 GO:0046034 ATP metabolic process 19/742 277/18722 0.0147246797194322 0.0902480369900685 GAPDH/APP/LDHA/COX6A1/ALDOA/TMSB4X/TPI1/HSPA1A/ENO1/HSPA1B/NCOR1/ATP6V1B1/NDUFB9/PKM/PARP1/UQCRH/COX8C/RHOA/COX5A 19 GO:1901216 positive regulation of neuron death 9/742 97/18722 0.0147649521968364 0.0903827309199157 JUN/FOS/GRN/EGR1/NF1/DDIT3/PARP1/CDC42/RHOA 9 GO:0006096 glycolytic process 8/742 81/18722 0.0148095571126323 0.0904316590066793 GAPDH/APP/LDHA/ALDOA/TPI1/ENO1/NCOR1/PKM 8 GO:1903533 regulation of protein targeting 8/742 81/18722 0.0148095571126323 0.0904316590066793 TCAF1/LMAN1/ANK3/STOM/NUCB1/HUWE1/LEPROT/UBE2L3 8 GO:0014074 response to purine-containing compound 12/742 148/18722 0.0148344572477266 0.0904718750663821 JUN/AKAP9/HSP90B1/FOS/HSPA5/APP/LDHA/FOSB/BSG/DUSP1/ZFP36L1/SLC6A4 12 GO:0032873 negative regulation of stress-activated MAPK cascade 6/742 51/18722 0.0150164049979289 0.0909224863499493 DUSP1/DLG1/NCOR1/PPIA/MARVELD3/PDCD4 6 GO:0051293 establishment of spindle localization 6/742 51/18722 0.0150164049979289 0.0909224863499493 ITGB1/DYNC1H1/GJA1/CFL1/KPNB1/DYNLT1 6 GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 6/742 51/18722 0.0150164049979289 0.0909224863499493 DUSP1/DLG1/NCOR1/PPIA/MARVELD3/PDCD4 6 GO:0007051 spindle organization 14/742 184/18722 0.0150262379249518 0.0909224863499493 DYNC1H1/ATRX/TACC2/TPR/HSPA1A/DLG1/HSPA1B/NCOR1/KPNB1/CLTC/RAN/NEK6/RHOA/RAB11A 14 GO:0043112 receptor metabolic process 13/742 166/18722 0.0150371804347993 0.0909224863499493 LRP1/ITGB1/LRPAP1/TFRC/CAV1/RNF43/CD81/ZNRF3/LGMN/FUT8/ADM/CLTC/SDCBP 13 GO:0060538 skeletal muscle organ development 13/742 166/18722 0.0150371804347993 0.0909224863499493 FOS/DAG1/PLEC/CAV1/EGR1/NR2F2/GPC1/DDX17/CITED2/DDX5/GPX1/RHOA/IGF2 13 GO:0061013 regulation of mRNA catabolic process 13/742 166/18722 0.0150371804347993 0.0909224863499493 FUS/ZFP36L1/NPM1/TNRC6A/TNRC6B/YBX1/ROCK1/PUM1/DHX36/CELF1/LARP1/CIRBP/HNRNPC 13 GO:0006401 RNA catabolic process 19/742 278/18722 0.0152413729580832 0.092044477277422 KCNQ1OT1/FUS/ZFP36L1/NPM1/TNRC6A/HSPA1A/UPF2/TNRC6B/YBX1/HSPA1B/ROCK1/PUM1/DHX36/CELF1/LARP1/CIRBP/DDX5/HNRNPC/SSB 19 GO:0045927 positive regulation of growth 18/742 259/18722 0.0153139639991173 0.0921362348421676 EGFR/LRP1/GOLGA4/MACF1/TGFBR3/PRKDC/CSH1/NRP1/SLC9A1/EIF4G1/S100A9/NIPBL/CELF1/CDC42/RHOA/IGF2/RAB11A/SDCBP 18 GO:0014015 positive regulation of gliogenesis 7/742 66/18722 0.0153311710607817 0.0921362348421676 LRP2/EGFR/SPINT1/DAG1/UFL1/IL6ST/HES1 7 GO:0019229 regulation of vasoconstriction 7/742 66/18722 0.0153311710607817 0.0921362348421676 EGFR/ATP2B1/CAV1/GJA1/GJA5/ADM/RHOA 7 GO:0042446 hormone biosynthetic process 7/742 66/18722 0.0153311710607817 0.0921362348421676 EGR1/POR/ATP1A1/ADM/CYP11A1/HSD17B1/CYP19A1 7 GO:0003333 amino acid transmembrane transport 9/742 98/18722 0.0157065770935682 0.0940120914910393 ITGB1/SLC3A2/SLC38A1/SLC43A2/SLC38A2/SLC1A5/SLC38A10/ARL6IP5/SLC38A9 9 GO:1902882 regulation of response to oxidative stress 9/742 98/18722 0.0157065770935682 0.0940120914910393 P4HB/MET/BMP7/PPIA/FUT8/TXN/HSPB1/GPX1/PARP1 9 GO:0007254 JNK cascade 13/742 167/18722 0.0157376670606681 0.0940120914910393 EGFR/APP/GADD45B/HACD3/IGF1R/DUSP9/NCOR1/RB1CC1/MARVELD3/GADD45G/CDC42/PDCD4/SDCBP 13 GO:1903034 regulation of response to wounding 13/742 167/18722 0.0157376670606681 0.0940120914910393 LRP1/GRN/ITGB1/CLDN4/KANK1/CAV1/GJA1/PLPP3/PTPRF/FERMT1/ANXA1/ACTG1/SRSF6 13 GO:0006757 ATP generation from ADP 8/742 82/18722 0.0158600462639179 0.0940120914910393 GAPDH/APP/LDHA/ALDOA/TPI1/ENO1/NCOR1/PKM 8 GO:2001252 positive regulation of chromosome organization 8/742 82/18722 0.0158600462639179 0.0940120914910393 ATRX/PPP1R10/MPHOSPH8/TPR/HNRNPA1/DHX36/RAD50/CCT3 8 GO:0044843 cell cycle G1/S phase transition 17/742 241/18722 0.0158663681877263 0.0940120914910393 EGFR/ITGB1/RPS6/SOX4/RPL26/ADAMTS1/PRKDC/ATP2B4/BRD4/ANXA1/CDK6/EIF4G1/DLG1/CTDSPL/BRD7/PSME2/CCNE1 17 GO:0035264 multicellular organism growth 11/742 132/18722 0.0159323787198743 0.0940120914910393 APP/PLEC/ATRX/ZFP36L1/LGMN/ADRB1/RBBP6/NIPBL/ARID5B/CELF1/IGF2 11 GO:0031579 membrane raft organization 4/742 25/18722 0.0159478001355245 0.0940120914910393 CAV1/DLG1/CLN3/S100A10 4 GO:0032469 endoplasmic reticulum calcium ion homeostasis 4/742 25/18722 0.0159478001355245 0.0940120914910393 APP/CCDC47/BCAP31/TGM2 4 GO:0032878 regulation of establishment or maintenance of cell polarity 4/742 25/18722 0.0159478001355245 0.0940120914910393 KANK1/ROCK1/GATA3/DOCK8 4 GO:0048143 astrocyte activation 4/742 25/18722 0.0159478001355245 0.0940120914910393 EGFR/LRP1/GRN/APP 4 GO:0061436 establishment of skin barrier 4/742 25/18722 0.0159478001355245 0.0940120914910393 CLDN4/MET/PLEC/LSR 4 GO:0090169 regulation of spindle assembly 4/742 25/18722 0.0159478001355245 0.0940120914910393 DYNC1H1/TPR/HSPA1A/HSPA1B 4 GO:0140448 signaling receptor ligand precursor processing 4/742 25/18722 0.0159478001355245 0.0940120914910393 CTSL/ENPEP/MME/ATP6AP2 4 GO:1903959 regulation of anion transmembrane transport 4/742 25/18722 0.0159478001355245 0.0940120914910393 TCAF1/ITGB1/SLC43A2/ARL6IP5 4 GO:0001771 immunological synapse formation 3/742 14/18722 0.0162728884962957 0.0949091725757979 CD81/DLG1/DOCK8 3 GO:0042921 glucocorticoid receptor signaling pathway 3/742 14/18722 0.0162728884962957 0.0949091725757979 CALR/ARID1A/PTGES3 3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 3/742 14/18722 0.0162728884962957 0.0949091725757979 RPL26/PMAIP1/DDX5 3 GO:0043558 regulation of translational initiation in response to stress 3/742 14/18722 0.0162728884962957 0.0949091725757979 PPP1R15A/NPM1/EIF2AK4 3 GO:0071236 cellular response to antibiotic 3/742 14/18722 0.0162728884962957 0.0949091725757979 HSPA5/RPL23/SLC9A1 3 GO:0086103 G protein-coupled receptor signaling pathway involved in heart process 3/742 14/18722 0.0162728884962957 0.0949091725757979 CAV1/ATP2B4/AKAP13 3 GO:0099188 postsynaptic cytoskeleton organization 3/742 14/18722 0.0162728884962957 0.0949091725757979 ACTG1/WASF2/PPP1R9A 3 GO:1901722 regulation of cell proliferation involved in kidney development 3/742 14/18722 0.0162728884962957 0.0949091725757979 EGR1/BMP7/GATA3 3 GO:1904294 positive regulation of ERAD pathway 3/742 14/18722 0.0162728884962957 0.0949091725757979 CAV1/TMEM259/BCAP31 3 GO:0008202 steroid metabolic process 21/742 319/18722 0.0163660712347841 0.095224867163497 LRP2/APP/SF1/DHCR24/SLC27A2/PBX1/EGR1/LRP5/POR/PRLR/LGMN/ATP1A1/MBTPS1/ACADVL/ADM/ASAH1/DHRS2/CYP11A1/HSD17B1/CYP19A1/CGA 21 GO:1901214 regulation of neuron death 21/742 319/18722 0.0163660712347841 0.095224867163497 JUN/FOS/LRP1/GRN/SERPINF1/DHCR24/EGR1/NRP1/ISL1/TMEM259/LGMN/NF1/EIF4G1/RASA1/ERBB3/DDIT3/GATA3/PARP1/CLN3/CDC42/RHOA 21 GO:0042596 fear response 5/742 38/18722 0.0164009428651801 0.095224867163497 GJA1/DPP4/EIF4G1/ADRB1/VDAC1 5 GO:0032206 positive regulation of telomere maintenance 6/742 52/18722 0.0164233981423683 0.095224867163497 ATRX/PPP1R10/HNRNPA1/DHX36/RAD50/CCT3 6 GO:0043392 negative regulation of DNA binding 6/742 52/18722 0.0164233981423683 0.095224867163497 JUN/TMSB4X/DDIT3/RSF1/NFKBIA/ID1 6 GO:0006165 nucleoside diphosphate phosphorylation 9/742 99/18722 0.0166915474309393 0.0965529792843559 GAPDH/APP/LDHA/ALDOA/TPI1/ENO1/NCOR1/NME3/PKM 9 GO:0033209 tumor necrosis factor-mediated signaling pathway 9/742 99/18722 0.0166915474309393 0.0965529792843559 KRT8/TMSB4X/HSPA1A/ACTN4/HSPA1B/SPPL2B/NFKBIA/KRT18/EIF5A 9 GO:0046328 regulation of JNK cascade 11/742 133/18722 0.0167703865262221 0.09689556659595 EGFR/APP/GADD45B/IGF1R/NCOR1/RB1CC1/MARVELD3/GADD45G/CDC42/PDCD4/SDCBP 11 GO:0006470 protein dephosphorylation 19/742 281/18722 0.0168771371807699 0.097350547200755 HSP90B1/SLC39A10/BOD1L1/DUSP1/DUSP6/PPP1R15A/PTPRF/DLG1/PTPRA/PTPN12/ROCK1/CTDSPL/PPIA/PTPN14/CALM1/PHPT1/CALM2/CSNK2B/YWHAE 19 GO:0071496 cellular response to external stimulus 21/742 320/18722 0.0168885463463658 0.097350547200755 JUN/EGFR/ATP2B1/FOS/HSPA5/SLC2A1/DAG1/PLEC/SLC38A2/GJA1/CTSV/TMEM150C/TNRC6A/FOLR1/SLC9A1/EIF4G1/PMAIP1/ATP1A1/HNRNPA1/LAMP2/EIF2AK4 21 GO:2001234 negative regulation of apoptotic signaling pathway 16/742 224/18722 0.0169986468235574 0.0978709968629061 TPT1/ITGAV/ITGA6/MIF/NRP1/HSPA1A/ENO1/PHIP/HSPA1B/TCF7L2/PPIA/RB1CC1/HSPB1/GPX1/SIAH2/VDAC2 16 GO:0042552 myelination 11/742 134/18722 0.0176408917568117 0.10145053001007 ITGB4/DAG1/CTSC/PLEC/JAM3/DEGS1/GPC1/NF1/NCSTN/DLG1/HEXB 11 GO:0006898 receptor-mediated endocytosis 17/742 244/18722 0.0177002837813983 0.101556153193697 LRP2/CTSL/LRP1/ITGAV/ITGB1/LRPAP1/AAK1/TFRC/CAV1/FOLR1/CD81/CANX/ADM/CLTC/CLN3/CLTA/SDCBP 17 GO:0019218 regulation of steroid metabolic process 9/742 100/18722 0.0177209319945277 0.101556153193697 SF1/EGR1/POR/ATP1A1/MBTPS1/ACADVL/ADM/ASAH1/CGA 9 GO:0061640 cytoskeleton-dependent cytokinesis 9/742 100/18722 0.0177209319945277 0.101556153193697 SON/RHOB/PLEC/MYH10/ANK3/SPTBN1/RASA1/ROCK1/RHOA 9 GO:0010812 negative regulation of cell-substrate adhesion 7/742 68/18722 0.0178432129342885 0.101628475913995 FBLN1/LRP1/KANK1/TACSTD2/ACTN4/RASA1/RHOA 7 GO:0061912 selective autophagy 7/742 68/18722 0.0178432129342885 0.101628475913995 UFL1/VPS13C/RB1CC1/HUWE1/VDAC1/TEX264/UFC1 7 GO:1901016 regulation of potassium ion transmembrane transporter activity 7/742 68/18722 0.0178432129342885 0.101628475913995 AKAP9/ITGB1/CAV1/ANK3/DLG1/VAMP2/YWHAE 7 GO:1903828 negative regulation of cellular protein localization 10/742 117/18722 0.0178813491989565 0.101628475913995 LMAN1/FERMT1/TMEM59/OS9/MAGED1/HECTD1/TXN/TRIM29/CLTC/LEPROT 10 GO:0007566 embryo implantation 6/742 53/18722 0.0179187049637834 0.101628475913995 FBLN1/ITGB4/BSG/GJA1/PRLR/CALR 6 GO:0008347 glial cell migration 6/742 53/18722 0.0179187049637834 0.101628475913995 LRP1/ADGRG1/LAMB1/RTN4/GLI3/HEXB 6 GO:0051438 regulation of ubiquitin-protein transferase activity 6/742 53/18722 0.0179187049637834 0.101628475913995 RPS20/RPL23/RPS2/SKP1/UBE2L3/UBE2C 6 GO:1990090 cellular response to nerve growth factor stimulus 6/742 53/18722 0.0179187049637834 0.101628475913995 HSPA5/APP/BPTF/KIDINS220/ID1/ARPC3 6 GO:2000772 regulation of cellular senescence 6/742 53/18722 0.0179187049637834 0.101628475913995 PRKDC/CDK6/YBX1/YPEL3/NEK6/HMGA1 6 GO:0043487 regulation of RNA stability 13/742 170/18722 0.0179886624829113 0.101908248469704 FUS/ZFP36L1/NPM1/TNRC6A/TNRC6B/YBX1/ROCK1/PUM1/DHX36/CELF1/LARP1/CIRBP/HNRNPC 13 GO:0006112 energy reserve metabolic process 8/742 84/18722 0.0181208332426529 0.102071740272184 GAA/IL6ST/AGL/RB1CC1/PTGES3/IGF2/PYGL/UGP2 8 GO:0006405 RNA export from nucleus 8/742 84/18722 0.0181208332426529 0.102071740272184 NPM1/TPR/PABPN1/UPF2/HNRNPA1/THOC2/RAN/SSB 8 GO:0006835 dicarboxylic acid transport 8/742 84/18722 0.0181208332426529 0.102071740272184 LRP2/SLC26A2/ITGB1/GJA1/SLC1A5/SLC19A1/ARL6IP5/FOLR1 8 GO:0010921 regulation of phosphatase activity 8/742 84/18722 0.0181208332426529 0.102071740272184 HSP90B1/SLC39A10/BOD1L1/PPP1R15A/ROCK1/CALM1/CALM2/CSNK2B 8 GO:0042310 vasoconstriction 8/742 84/18722 0.0181208332426529 0.102071740272184 EGFR/ATP2B1/CAV1/GJA1/SLC6A4/GJA5/ADM/RHOA 8 GO:0050679 positive regulation of epithelial cell proliferation 15/742 207/18722 0.0181590050982025 0.10217025647508 EGFR/NRP2/GRN/LAMB1/LAMC1/RTN4/NRP1/MYDGF/EMC10/TCF7L2/SRSF6/KDM5B/ID1/CDC42/IGF2 15 GO:0046621 negative regulation of organ growth 5/742 39/18722 0.0182166802009605 0.102261818400846 GJA1/SLC6A4/CITED2/YY1/CGA 5 GO:0090224 regulation of spindle organization 5/742 39/18722 0.0182166802009605 0.102261818400846 DYNC1H1/TPR/HSPA1A/HSPA1B/CLTC 5 GO:0033598 mammary gland epithelial cell proliferation 4/742 26/18722 0.0182705452229372 0.102331625171553 RTN4/KDM5B/GATA3/GPX1 4 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 4/742 26/18722 0.0182705452229372 0.102331625171553 SLC39A10/KCNN4/CD81/FOXP1 4 GO:0046939 nucleotide phosphorylation 9/742 101/18722 0.018795786214293 0.105154228650745 GAPDH/APP/LDHA/ALDOA/TPI1/ENO1/NCOR1/NME3/PKM 9 GO:0022612 gland morphogenesis 10/742 118/18722 0.0188695693613245 0.105328443666602 LAMA5/DAG1/CAV1/LRP5/NRP1/BMP7/GLI3/KDM5B/CDC42/TGM2 10 GO:1903313 positive regulation of mRNA metabolic process 10/742 118/18722 0.0188695693613245 0.105328443666602 ZFP36L1/TNRC6A/TRA2B/TNRC6B/ROCK1/PUM1/DHX36/CELF1/CIRBP/PRDX6 10 GO:0034605 cellular response to heat 7/742 69/18722 0.019201975851868 0.107062935336601 TPR/HSPA1A/HSPA1B/SLC52A3/DHX36/DNAJB1/YWHAE 7 GO:0007272 ensheathment of neurons 11/742 136/18722 0.0194822288906178 0.108258954690272 ITGB4/DAG1/CTSC/PLEC/JAM3/DEGS1/GPC1/NF1/NCSTN/DLG1/HEXB 11 GO:0008366 axon ensheathment 11/742 136/18722 0.0194822288906178 0.108258954690272 ITGB4/DAG1/CTSC/PLEC/JAM3/DEGS1/GPC1/NF1/NCSTN/DLG1/HEXB 11 GO:1900180 regulation of protein localization to nucleus 11/742 136/18722 0.0194822288906178 0.108258954690272 CDH1/TFRC/NPM1/TPR/FERMT1/GLI3/MAGED1/TRIM29/PARP1/RAN/CCT3 11 GO:1990138 neuron projection extension 13/742 172/18722 0.0196190701295179 0.108298897010834 NRP2/LRP1/ITGB1/GOLGA4/SEMA6A/MACF1/IQGAP1/SEMA6D/RTN4/NRP1/USP9X/EIF2AK4/RAB11A 13 GO:0007605 sensory perception of sound 12/742 154/18722 0.0196970277491459 0.108298897010834 LRP2/NIPBL/DIAPH1/PGAP1/TRIOBP/SLC52A3/DDIT3/ATP6V1B1/NDUFB9/TBL1X/GPX1/HEXB 12 GO:0045786 negative regulation of cell cycle 24/742 385/18722 0.0197012757763704 0.108298897010834 EGFR/RHOB/DUSP1/ATRX/SOX4/RPL26/PRKDC/ZFP36L1/PPP1R10/NPM1/BMP7/TPR/NR2F2/CDK6/BTG1/DLG1/TP53I13/CTDSPL/EIF2AK4/BRD7/GATA3/HPGD/PDCD4/LCMT1 24 GO:0010452 histone H3-K36 methylation 3/742 15/18722 0.0197524911349719 0.108298897010834 BRD4/ASH1L/NSD1 3 GO:0019511 peptidyl-proline hydroxylation 3/742 15/18722 0.0197524911349719 0.108298897010834 P4HB/P3H1/PRDX4 3 GO:0031958 corticosteroid receptor signaling pathway 3/742 15/18722 0.0197524911349719 0.108298897010834 CALR/ARID1A/PTGES3 3 GO:0048569 post-embryonic animal organ development 3/742 15/18722 0.0197524911349719 0.108298897010834 FBN1/EFEMP1/LDHA 3 GO:0051284 positive regulation of sequestering of calcium ion 3/742 15/18722 0.0197524911349719 0.108298897010834 GSTO1/CALM1/CALM2 3 GO:0098760 response to interleukin-7 3/742 15/18722 0.0197524911349719 0.108298897010834 P4HB/PDIA3/YBX1 3 GO:0098761 cellular response to interleukin-7 3/742 15/18722 0.0197524911349719 0.108298897010834 P4HB/PDIA3/YBX1 3 GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response 3/742 15/18722 0.0197524911349719 0.108298897010834 HSPA5/UFL1/PPP1R15A 3 GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 3/742 15/18722 0.0197524911349719 0.108298897010834 ZFP36L1/TNRC6B/DHX36 3 GO:1904063 negative regulation of cation transmembrane transport 9/742 102/18722 0.0199171506470958 0.109080625495181 CAV1/SLC43A2/ANK3/C4orf3/GSTO1/CALM1/VDAC1/CALM2/YWHAE 9 GO:0009914 hormone transport 20/742 306/18722 0.0201565794693753 0.109923821981598 EGFR/LRP1/SOX4/GJA1/DPP4/DYNLL1/LRP5/ISL1/ANXA1/KIF5B/TCF7L2/SYT7/ADM/KDM5B/SLC16A1/GATA3/HMGN3/PHPT1/CYP19A1/CGA 20 GO:0045740 positive regulation of DNA replication 5/742 40/18722 0.0201601179585685 0.109923821981598 JUN/EGFR/ATRX/CDC42/CACYBP 5 GO:0071526 semaphorin-plexin signaling pathway 5/742 40/18722 0.0201601179585685 0.109923821981598 NRP2/SEMA6A/MET/SEMA6D/NRP1 5 GO:1901020 negative regulation of calcium ion transmembrane transporter activity 5/742 40/18722 0.0201601179585685 0.109923821981598 C4orf3/GSTO1/CALM1/CALM2/YWHAE 5 GO:0021537 telencephalon development 17/742 248/18722 0.0203949925731786 0.111081877961965 LRP1/ADGRG1/SLC2A1/LAMB1/SLC38A2/RTN4/TACC2/ATP2B4/CDK6/GLI3/KIF5B/NF1/TRA2B/CELF1/HES1/RHOA/ANXA3 17 GO:0045444 fat cell differentiation 16/742 229/18722 0.0204714305388714 0.111375404033067 ZFP36L1/LRP5/BMP7/ANKRD26/ADRB1/NIPBL/TCF7L2/CDS1/SDF4/DDIT3/ARID5B/GATA3/ARL4A/GPX1/ADIRF/HES1 16 GO:2001251 negative regulation of chromosome organization 8/742 86/18722 0.0206035839126136 0.11164727833952 DUSP1/ATRX/TPR/HNRNPA1/RAD50/PARP1/HNRNPC/LCMT1 8 GO:0007519 skeletal muscle tissue development 12/742 155/18722 0.0206109148372433 0.11164727833952 FOS/PLEC/CAV1/EGR1/NR2F2/GPC1/DDX17/CITED2/DDX5/GPX1/RHOA/IGF2 12 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 4/742 27/18722 0.0207926105409632 0.11164727833952 GSTO1/SLC9A1/CALM1/CALM2 4 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 4/742 27/18722 0.0207926105409632 0.11164727833952 APP/PBX1/BRD4/RAB11A 4 GO:0018126 protein hydroxylation 4/742 27/18722 0.0207926105409632 0.11164727833952 P4HB/ASPH/P3H1/PRDX4 4 GO:0031954 positive regulation of protein autophosphorylation 4/742 27/18722 0.0207926105409632 0.11164727833952 IQGAP1/RAD50/CALM1/CALM2 4 GO:0033561 regulation of water loss via skin 4/742 27/18722 0.0207926105409632 0.11164727833952 CLDN4/MET/PLEC/LSR 4 GO:0033688 regulation of osteoblast proliferation 4/742 27/18722 0.0207926105409632 0.11164727833952 ITGAV/LRP5/ATRAID/RHOA 4 GO:0034453 microtubule anchoring 4/742 27/18722 0.0207926105409632 0.11164727833952 DAG1/GCC2/CEP350/PCM1 4 GO:0061437 renal system vasculature development 4/742 27/18722 0.0207926105409632 0.11164727833952 EGR1/NRP1/BMP7/HES1 4 GO:0061440 kidney vasculature development 4/742 27/18722 0.0207926105409632 0.11164727833952 EGR1/NRP1/BMP7/HES1 4 GO:0070861 regulation of protein exit from endoplasmic reticulum 4/742 27/18722 0.0207926105409632 0.11164727833952 GCC2/CD81/OS9/BCAP31 4 GO:0032411 positive regulation of transporter activity 10/742 120/18722 0.0209653536133096 0.112452602442725 AKAP9/TCAF1/ANK3/GSTO1/TMSB4X/SLC9A1/KIF5B/ACTN4/CALM1/CALM2 10 GO:0009135 purine nucleoside diphosphate metabolic process 9/742 103/18722 0.021086049481667 0.112732775367354 GAPDH/APP/LDHA/ALDOA/TPI1/ENO1/DLG1/NCOR1/PKM 9 GO:0009179 purine ribonucleoside diphosphate metabolic process 9/742 103/18722 0.021086049481667 0.112732775367354 GAPDH/APP/LDHA/ALDOA/TPI1/ENO1/DLG1/NCOR1/PKM 9 GO:0090277 positive regulation of peptide hormone secretion 9/742 103/18722 0.021086049481667 0.112732775367354 EGFR/LRP1/SOX4/GJA1/DYNLL1/ISL1/KIF5B/TCF7L2/PHPT1 9 GO:0046883 regulation of hormone secretion 17/742 249/18722 0.0211152690466599 0.112766950368108 EGFR/LRP1/SOX4/GJA1/DPP4/DYNLL1/LRP5/ISL1/ANXA1/KIF5B/TCF7L2/SYT7/KDM5B/SLC16A1/HMGN3/PHPT1/CYP19A1 17 GO:0038066 p38MAPK cascade 6/742 55/18722 0.0211835842267281 0.112887708824204 GADD45B/DUSP1/ZFP36L1/DLG1/EMC10/GADD45G 6 GO:0061614 pri-miRNA transcription by RNA polymerase II 6/742 55/18722 0.0211835842267281 0.112887708824204 JUN/FOS/EGR1/GATA3/DDX5/YY1 6 GO:0032273 positive regulation of protein polymerization 11/742 138/18722 0.0214620010288034 0.114248152028329 AKAP9/IQGAP2/MET/CLIP1/PFN1/HSPA1A/DLG1/WASF2/HSPA1B/ARPC3/RHOA 11 GO:1901342 regulation of vasculature development 22/742 348/18722 0.0215728719206349 0.114714733356229 GRN/ITGB1/SEMA6A/RHOB/SERPINF1/COL4A2/ADAMTS1/FLT1/NRP1/ATP2B4/ISL1/NF1/MYDGF/BTG1/ROCK1/EMC10/GTF2I/ADM/PKM/HSPB1/ID1/ANXA3 22 GO:0007029 endoplasmic reticulum organization 8/742 87/18722 0.0219314268655094 0.116245975016756 LMAN1/RTN4/CCDC47/MIA3/EMC1/EMC10/LMAN2/SEC61A1 8 GO:1900182 positive regulation of protein localization to nucleus 8/742 87/18722 0.0219314268655094 0.116245975016756 CDH1/TFRC/NPM1/TPR/GLI3/PARP1/RAN/CCT3 8 GO:2000177 regulation of neural precursor cell proliferation 8/742 87/18722 0.0219314268655094 0.116245975016756 LRP2/SPINT1/ADGRG1/SPINT2/SLC6A4/GLI3/NF1/RHOA 8 GO:0043523 regulation of neuron apoptotic process 15/742 212/18722 0.0219976145687379 0.116471828477562 JUN/LRP1/GRN/NRP1/ISL1/LGMN/NF1/RASA1/ERBB3/DDIT3/GATA3/PARP1/CLN3/CDC42/RHOA 15 GO:0042177 negative regulation of protein catabolic process 10/742 121/18722 0.0220745778986299 0.11675419145528 EGFR/MYCBP2/RPL23/CTSA/ROCK1/CST3/TIMP3/EIF3H/ATRAID/SDCBP 10 GO:0061515 myeloid cell development 7/742 71/18722 0.0221334397779198 0.116940312837352 FBN1/APP/RPS6/ATP6AP1/WASF2/FOXP1/CITED2 7 GO:0071634 regulation of transforming growth factor beta production 5/742 41/18722 0.0222343064561285 0.117347728518456 CD46/ITGAV/LTBP1/FERMT1/ATP6AP2 5 GO:0022900 electron transport chain 13/742 175/18722 0.0222694592217046 0.117407821296927 COX6A1/GLDC/PLEC/POR/DEGS1/ASPH/NDUFB9/UQCRH/DHRS2/COX8C/CYP19A1/COX5A/ETFA 13 GO:0051783 regulation of nuclear division 11/742 139/18722 0.0225055244187134 0.118525896192371 DUSP1/LRP5/BMP7/TPR/CALR/PHIP/OBSL1/CDC42/IGF2/ANAPC11/LCMT1 11 GO:0051047 positive regulation of secretion 20/742 310/18722 0.0227922983394976 0.119908364001191 EGFR/LRP1/KCNN4/WLS/MYH10/SOX4/GJA1/SLC6A4/DYNLL1/ATP6AP1/ISL1/FRMD4A/KIF5B/TCF7L2/SYT7/PPIA/LAMP1/PHPT1/CYP19A1/SDCBP 20 GO:0051653 spindle localization 6/742 56/18722 0.0229575618015452 0.12039315849218 ITGB1/DYNC1H1/GJA1/CFL1/KPNB1/DYNLT1 6 GO:1904645 response to amyloid-beta 6/742 56/18722 0.0229575618015452 0.12039315849218 LRP1/APP/GJA1/IGF1R/LGMN/PARP1 6 GO:1990089 response to nerve growth factor 6/742 56/18722 0.0229575618015452 0.12039315849218 HSPA5/APP/BPTF/KIDINS220/ID1/ARPC3 6 GO:0043534 blood vessel endothelial cell migration 13/742 176/18722 0.0232095343623116 0.121585471632894 ITGB1/EPHB4/NRP1/ATP2B4/MIA3/TMSB4X/ANXA1/NF1/HSPB1/GPX1/ID1/RHOA/CSNK2B 13 GO:0007159 leukocyte cell-cell adhesion 23/742 371/18722 0.0233750448194418 0.121613692164925 CD46/ITGB1/TFRC/CAV1/SOX4/IL6ST/DPP4/DLG5/BMP7/MIA3/NFAT5/CD81/ANXA1/GLI3/S100A9/DLG1/ROCK1/CD55/GATA3/DOCK8/HES1/RHOA/IGF2 23 GO:0006516 glycoprotein catabolic process 4/742 28/18722 0.0235179284216942 0.121613692164925 CTSL/MANBA/GPC1/CST3 4 GO:0051894 positive regulation of focal adhesion assembly 4/742 28/18722 0.0235179284216942 0.121613692164925 IQGAP1/NRP1/ROCK1/S100A10 4 GO:0090344 negative regulation of cell aging 4/742 28/18722 0.0235179284216942 0.121613692164925 MIF/PRKDC/CDK6/YBX1 4 GO:0003002 regionalization 21/742 331/18722 0.0235393674468003 0.121613692164925 LRP2/NRP2/ADGRG1/WLS/BPTF/PBX1/PRKDC/LRP5/NRP1/ISL1/NR2F2/GLI3/ATP6AP2/TRA2B/PGAP1/IRX2/DDIT3/TMEM107/CITED2/HES1/YY1 21 GO:0030073 insulin secretion 14/742 195/18722 0.0235744945631499 0.121613692164925 LRP1/SOX4/GJA1/DPP4/DYNLL1/LRP5/ISL1/ANXA1/KIF5B/TCF7L2/SYT7/SLC16A1/HMGN3/PHPT1 14 GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin 3/742 16/18722 0.0236088119000331 0.121613692164925 ENPEP/MME/ATP6AP2 3 GO:0009415 response to water 3/742 16/18722 0.0236088119000331 0.121613692164925 PLEC/KRT8/ATP2B4 3 GO:0019377 glycolipid catabolic process 3/742 16/18722 0.0236088119000331 0.121613692164925 HEXA/FUCA1/HEXB 3 GO:0021783 preganglionic parasympathetic fiber development 3/742 16/18722 0.0236088119000331 0.121613692164925 NRP2/NRP1/HES1 3 GO:0033631 cell-cell adhesion mediated by integrin 3/742 16/18722 0.0236088119000331 0.121613692164925 ITGB1/PLPP3/DPP4 3 GO:0061684 chaperone-mediated autophagy 3/742 16/18722 0.0236088119000331 0.121613692164925 EEF1A1/CTSA/LAMP2 3 GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 3/742 16/18722 0.0236088119000331 0.121613692164925 HSPA1A/HSPA1B/NFKBIA 3 GO:0090231 regulation of spindle checkpoint 3/742 16/18722 0.0236088119000331 0.121613692164925 DUSP1/TPR/LCMT1 3 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint 3/742 16/18722 0.0236088119000331 0.121613692164925 DUSP1/TPR/LCMT1 3 GO:1903504 regulation of mitotic spindle checkpoint 3/742 16/18722 0.0236088119000331 0.121613692164925 DUSP1/TPR/LCMT1 3 GO:0071479 cellular response to ionizing radiation 7/742 72/18722 0.023709362603635 0.122004428397872 HSPA5/RHOB/RPL26/EGR1/NIPBL/TMEM109/GATA3 7 GO:0045862 positive regulation of proteolysis 23/742 372/18722 0.0240221694170339 0.123485449448645 FBLN1/GRN/APP/CLDN4/CTSD/CTSC/CAV1/ARL6IP5/TMEM259/HSPA1A/ENO1/ASPH/LGMN/NCSTN/S100A9/PMAIP1/HSPA1B/HECTD1/PCOLCE2/BCAP31/RHOA/DDA1/PSME2 23 GO:0071453 cellular response to oxygen levels 13/742 177/18722 0.0241787395111814 0.124099819509478 MALAT1/P4HB/CAV1/EGR1/ZFP36L1/ATP6AP1/BMP7/SLC9A1/ENO1/PMAIP1/HP1BP3/CITED2/EPAS1 13 GO:0097305 response to alcohol 17/742 253/18722 0.0241919283780623 0.124099819509478 ATP2B1/FOS/CDH1/DAG1/FOSB/TGFBR3/RPL15/EEF1B2/GLB1/SDF4/LARP1/CALM1/TUFM/GATA3/PARP1/RHOA/HPGD 17 GO:0042391 regulation of membrane potential 26/742 434/18722 0.0244404614251941 0.124696996149502 JUN/AKAP9/APP/KCNN4/CAV1/GJA1/DSP/DSG2/DSC2/ANK3/GABRE/ARL6IP5/GJA5/SLC25A36/SLC9A1/KIF5B/PMAIP1/ADRB1/DLG1/PPP1R9A/ATP1A1/GNAQ/CALM1/PARP1/CLN3/YWHAE 26 GO:0021795 cerebral cortex cell migration 5/742 42/18722 0.0244420544272698 0.124696996149502 ADGRG1/LAMB1/RTN4/GLI3/RHOA 5 GO:0035019 somatic stem cell population maintenance 5/742 42/18722 0.0244420544272698 0.124696996149502 SOX4/LRP5/BMP7/HES1/LBH 5 GO:0045047 protein targeting to ER 5/742 42/18722 0.0244420544272698 0.124696996149502 HSPA5/SEC62/SEC61A1/SEC63/SPCS2 5 GO:0045773 positive regulation of axon extension 5/742 42/18722 0.0244420544272698 0.124696996149502 LRP1/GOLGA4/MACF1/NRP1/RAB11A 5 GO:0048588 developmental cell growth 16/742 234/18722 0.0244597953985562 0.124696996149502 NRP2/LRP1/APP/ITGB1/GOLGA4/SEMA6A/MACF1/IQGAP1/SEMA6D/RTN4/NRP1/AKAP13/USP9X/EIF2AK4/YY1/RAB11A 16 GO:0090276 regulation of peptide hormone secretion 14/742 196/18722 0.0245013699140268 0.124780172551848 EGFR/LRP1/SOX4/GJA1/DPP4/DYNLL1/LRP5/ISL1/KIF5B/TCF7L2/SYT7/SLC16A1/HMGN3/PHPT1 14 GO:0032200 telomere organization 12/742 159/18722 0.0245835838988945 0.12506993250313 ATRX/PRKDC/PPP1R10/HNRNPA1/DHX36/RIF1/RAD50/PARP1/HNRNPC/PTGES3/CCNE1/CCT3 12 GO:0002793 positive regulation of peptide secretion 9/742 106/18722 0.024887918098338 0.125840650364166 EGFR/LRP1/SOX4/GJA1/DYNLL1/ISL1/KIF5B/TCF7L2/PHPT1 9 GO:0006090 pyruvate metabolic process 9/742 106/18722 0.024887918098338 0.125840650364166 GAPDH/APP/LDHA/ALDOA/TPI1/ENO1/NCOR1/PKM/VDAC1 9 GO:0009185 ribonucleoside diphosphate metabolic process 9/742 106/18722 0.024887918098338 0.125840650364166 GAPDH/APP/LDHA/ALDOA/TPI1/ENO1/DLG1/NCOR1/PKM 9 GO:0046620 regulation of organ growth 9/742 106/18722 0.024887918098338 0.125840650364166 TGFBR3/GJA1/DUSP6/SLC6A4/DUSP9/CITED2/YY1/IGF2/CGA 9 GO:0046822 regulation of nucleocytoplasmic transport 9/742 106/18722 0.024887918098338 0.125840650364166 CDH1/TPR/FERMT1/GLI3/TCF7L2/PTPN14/TXN/RAN/YWHAE 9 GO:0090263 positive regulation of canonical Wnt signaling pathway 9/742 106/18722 0.024887918098338 0.125840650364166 EGFR/LGR5/KANK1/WLS/CAV1/LGR4/SOX4/ATP6AP2/TBL1X 9 GO:0035924 cellular response to vascular endothelial growth factor stimulus 7/742 73/18722 0.0253607975978941 0.127969703915829 NRP2/SEMA6A/FLT1/NRP1/ATP2B4/ANXA1/HSPB1 7 GO:0042274 ribosomal small subunit biogenesis 7/742 73/18722 0.0253607975978941 0.127969703915829 RPS21/RPS6/RPS16/RPS25/PRKDC/NPM1/RPS17 7 GO:0050870 positive regulation of T cell activation 15/742 216/18722 0.0254853529670032 0.128466983323465 CD46/TFRC/CAV1/SOX4/IL6ST/DPP4/CD81/ANXA1/GLI3/CD55/GATA3/DOCK8/HES1/RHOA/IGF2 15 GO:0009132 nucleoside diphosphate metabolic process 10/742 124/18722 0.0256572867727129 0.129201831454844 GAPDH/APP/LDHA/ALDOA/TPI1/ENO1/DLG1/NCOR1/NME3/PKM 10 GO:0050729 positive regulation of inflammatory response 11/742 142/18722 0.025858724524775 0.129951270755227 EGFR/NEAT1/GRN/APP/CTSC/IL6ST/CD81/S100A9/NFKBIA/TGM2/PDCD4 11 GO:2000045 regulation of G1/S transition of mitotic cell cycle 11/742 142/18722 0.025858724524775 0.129951270755227 EGFR/SOX4/RPL26/ADAMTS1/PRKDC/ANXA1/EIF4G1/DLG1/CTDSPL/BRD7/PSME2 11 GO:0005976 polysaccharide metabolic process 9/742 107/18722 0.0262568182367261 0.131511092651723 GAA/IL6ST/AGL/RB1CC1/CLTC/PTGES3/IGF2/PYGL/UGP2 9 GO:0032392 DNA geometric change 8/742 90/18722 0.0262755968516702 0.131511092651723 ATRX/ANXA1/PURA/CHD2/DHX36/HMGB3/RAD50/HMGA1 8 GO:0034644 cellular response to UV 8/742 90/18722 0.0262755968516702 0.131511092651723 RPL26/NPM1/MME/DDB1/DHX36/EIF2AK4/PARP1/YY1 8 GO:0046031 ADP metabolic process 8/742 90/18722 0.0262755968516702 0.131511092651723 GAPDH/APP/LDHA/ALDOA/TPI1/ENO1/NCOR1/PKM 8 GO:0019082 viral protein processing 4/742 29/18722 0.0264497838197029 0.131583013161463 CANX/MAN2A1/MOGS/FUT8 4 GO:0021522 spinal cord motor neuron differentiation 4/742 29/18722 0.0264497838197029 0.131583013161463 SOX4/LMO4/ISL1/GLI3 4 GO:0021602 cranial nerve morphogenesis 4/742 29/18722 0.0264497838197029 0.131583013161463 NRP2/NRP1/GLI3/CITED2 4 GO:0022011 myelination in peripheral nervous system 4/742 29/18722 0.0264497838197029 0.131583013161463 ITGB4/DAG1/PLEC/NF1 4 GO:0032292 peripheral nervous system axon ensheathment 4/742 29/18722 0.0264497838197029 0.131583013161463 ITGB4/DAG1/PLEC/NF1 4 GO:0060969 negative regulation of gene silencing 4/742 29/18722 0.0264497838197029 0.131583013161463 NEAT1/KCNQ1OT1/NCOR1/ADAR 4 GO:0001709 cell fate determination 5/742 43/18722 0.0267859236337668 0.132121738972303 ISL1/IFRD1/GATA3/HES1/CDC42 5 GO:0006509 membrane protein ectodomain proteolysis 5/742 43/18722 0.0267859236337668 0.132121738972303 DAG1/NCSTN/ROCK1/TIMP3/SPPL2B 5 GO:0010171 body morphogenesis 5/742 43/18722 0.0267859236337668 0.132121738972303 DAG1/ANKRD11/ATP6AP2/NIPBL/ARID5B 5 GO:0031952 regulation of protein autophosphorylation 5/742 43/18722 0.0267859236337668 0.132121738972303 CAV1/IQGAP1/RAD50/CALM1/CALM2 5 GO:0061383 trabecula morphogenesis 5/742 43/18722 0.0267859236337668 0.132121738972303 FBN2/TGFBR3/ADAMTS1/BMP7/RHOA 5 GO:0120178 steroid hormone biosynthetic process 5/742 43/18722 0.0267859236337668 0.132121738972303 EGR1/ADM/CYP11A1/HSD17B1/CYP19A1 5 GO:0035904 aorta development 6/742 58/18722 0.0267987818725198 0.132121738972303 LRP2/LRP1/ADAMTS6/SOX4/HECTD1/HES1 6 GO:0042743 hydrogen peroxide metabolic process 6/742 58/18722 0.0267987818725198 0.132121738972303 EGFR/GPX3/PRDX6/GPX1/PRDX4/HBA2 6 GO:0043525 positive regulation of neuron apoptotic process 6/742 58/18722 0.0267987818725198 0.132121738972303 JUN/GRN/NF1/DDIT3/CDC42/RHOA 6 GO:0038061 NIK/NF-kappaB signaling 11/742 143/18722 0.0270528573974431 0.133154906893408 EGFR/APP/BMP7/CALR/TMSB4X/NFAT5/TRIM44/ACTN4/NFKBIA/RHOA/PDCD4 11 GO:0120192 tight junction assembly 7/742 74/18722 0.0270892067667764 0.133154906893408 CLDN4/GJA1/LSR/ACTG1/DLG1/ROCK1/MARVELD3 7 GO:1903201 regulation of oxidative stress-induced cell death 7/742 74/18722 0.0270892067667764 0.133154906893408 P4HB/MET/PPIA/TXN/HSPB1/GPX1/PARP1 7 GO:0019318 hexose metabolic process 16/742 237/18722 0.0271178884131046 0.133163388430156 GAPDH/GAA/ALDOA/LRP5/FUCA1/TPI1/ENO1/DDB1/PMAIP1/MAN2A1/RANBP2/GLB1/FUT8/SLC35B4/IGF2/LCMT1 16 GO:0007033 vacuole organization 13/742 180/18722 0.0272659842888121 0.13362496268525 GRN/GAA/NAGLU/HOOK2/ATP6AP2/MAN2A1/SYT7/MBTPS1/TMEM165/GNPTAB/RB1CC1/CLN3/HEXB 13 GO:0048660 regulation of smooth muscle cell proliferation 13/742 180/18722 0.0272659842888121 0.13362496268525 JUN/EGFR/SF1/GJA1/ADAMTS1/PRKDC/TCF7L2/FOXP1/GNA12/TGM2/RHOA/HPGD/PDCD4 13 GO:0007409 axonogenesis 25/742 418/18722 0.0274322220095999 0.134306418956812 NRP2/LRP1/LAMA5/APP/ITGB1/DAG1/GOLGA4/SEMA6A/MYCBP2/MACF1/BSG/RPL24/EPHB4/SEMA6D/ANK3/RTN4/NRP1/BMP7/ISL1/GLI3/KIF5B/USP9X/GATA3/SIAH1/RAB11A 25 GO:0033138 positive regulation of peptidyl-serine phosphorylation 9/742 108/18722 0.0276780778016952 0.134842257778154 EGFR/AKAP9/APP/TFRC/CAV1/MIF/ATP2B4/EIF4G1/TXN 9 GO:0010715 regulation of extracellular matrix disassembly 3/742 17/18722 0.027841923670793 0.134842257778154 LRP1/DPP4/CST3 3 GO:0016264 gap junction assembly 3/742 17/18722 0.027841923670793 0.134842257778154 CAV1/GJA1/GJA5 3 GO:0036035 osteoclast development 3/742 17/18722 0.027841923670793 0.134842257778154 FBN1/ATP6AP1/FOXP1 3 GO:0042339 keratan sulfate metabolic process 3/742 17/18722 0.027841923670793 0.134842257778154 B4GAT1/GNS/GLB1 3 GO:0045198 establishment of epithelial cell apical/basal polarity 3/742 17/18722 0.027841923670793 0.134842257778154 FAT1/CDC42/RHOA 3 GO:0046827 positive regulation of protein export from nucleus 3/742 17/18722 0.027841923670793 0.134842257778154 TPR/TCF7L2/YWHAE 3 GO:0048532 anatomical structure arrangement 3/742 17/18722 0.027841923670793 0.134842257778154 NRP2/HSPA5/NRP1 3 GO:0060977 coronary vasculature morphogenesis 3/742 17/18722 0.027841923670793 0.134842257778154 LRP2/TGFBR3/NRP1 3 GO:0061450 trophoblast cell migration 3/742 17/18722 0.027841923670793 0.134842257778154 ITGB4/GJA1/CALR 3 GO:0090083 regulation of inclusion body assembly 3/742 17/18722 0.027841923670793 0.134842257778154 HSPA1A/HSPA1B/DNAJB1 3 GO:0106106 cold-induced thermogenesis 11/742 144/18722 0.0282862583316077 0.136726141054933 DYNC1H1/CAV1/LGR4/GJA1/IGF1R/PRLR/ADRB1/DDIT3/EPAS1/ID1/GADD45G 11 GO:0120161 regulation of cold-induced thermogenesis 11/742 144/18722 0.0282862583316077 0.136726141054933 DYNC1H1/CAV1/LGR4/GJA1/IGF1R/PRLR/ADRB1/DDIT3/EPAS1/ID1/GADD45G 11 GO:0045766 positive regulation of angiogenesis 13/742 181/18722 0.0283565314398506 0.136798110657092 GRN/ITGB1/RHOB/FLT1/NRP1/ISL1/MYDGF/BTG1/EMC10/ADM/PKM/HSPB1/ANXA3 13 GO:1904018 positive regulation of vasculature development 13/742 181/18722 0.0283565314398506 0.136798110657092 GRN/ITGB1/RHOB/FLT1/NRP1/ISL1/MYDGF/BTG1/EMC10/ADM/PKM/HSPB1/ANXA3 13 GO:0002791 regulation of peptide secretion 14/742 200/18722 0.0284813953249132 0.137266432102508 EGFR/LRP1/SOX4/GJA1/DPP4/DYNLL1/LRP5/ISL1/KIF5B/TCF7L2/SYT7/SLC16A1/HMGN3/PHPT1 14 GO:0030042 actin filament depolymerization 6/742 59/18722 0.0288697519843213 0.1385885222363 SPTAN1/SPTBN1/TRIOBP/CFL1/DSTN/CAPZB 6 GO:0032768 regulation of monooxygenase activity 6/742 59/18722 0.0288697519843213 0.1385885222363 EGFR/CAV1/ATP2B4/POR/CALM1/HM13 6 GO:0008088 axo-dendritic transport 7/742 75/18722 0.0288959874298359 0.1385885222363 ARMCX3/APP/DYNC1H1/DST/KIF5B/PURA/HSPB1 7 GO:0036465 synaptic vesicle recycling 7/742 75/18722 0.0288959874298359 0.1385885222363 ACTG1/CANX/KIAA1109/ROCK1/SYT7/VAMP2/CALM1 7 GO:0043627 response to estrogen 7/742 75/18722 0.0288959874298359 0.1385885222363 KRT19/LDHA/CAV1/GLI3/CITED2/GATA3/SERPINB9 7 GO:1903039 positive regulation of leukocyte cell-cell adhesion 16/742 239/18722 0.0290059160320208 0.138980819784852 CD46/TFRC/CAV1/SOX4/IL6ST/DPP4/NFAT5/CD81/ANXA1/GLI3/CD55/GATA3/DOCK8/HES1/RHOA/IGF2 16 GO:0071322 cellular response to carbohydrate stimulus 12/742 163/18722 0.0290908172620084 0.139038233801944 LRP1/SERPINF1/SOX4/ZFP36L1/DYNLL1/COLEC12/LRP5/IGF1R/KIF5B/TRA2B/HMGN3/PHPT1 12 GO:0072331 signal transduction by p53 class mediator 12/742 163/18722 0.0290908172620084 0.139038233801944 RPS20/ATRX/MIF/SOX4/RPL26/RPL23/NPM1/PMAIP1/TMEM109/DDX5/USP10/EIF5A 12 GO:0043266 regulation of potassium ion transport 9/742 109/18722 0.0291525929872388 0.139038233801944 AKAP9/ITGB1/KCNN4/CAV1/ANK3/KIF5B/DLG1/VAMP2/YWHAE 9 GO:0045124 regulation of bone resorption 5/742 44/18722 0.0292682246903871 0.139038233801944 EGFR/TFRC/ATP6AP1/NF1/LTBP3 5 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 5/742 44/18722 0.0292682246903871 0.139038233801944 DLG5/FAT1/DLG1/CDC42/RHOA 5 GO:0062208 positive regulation of pattern recognition receptor signaling pathway 5/742 44/18722 0.0292682246903871 0.139038233801944 CAV1/RTN4/HSPA1A/HSPA1B/PUM1 5 GO:0089718 amino acid import across plasma membrane 5/742 44/18722 0.0292682246903871 0.139038233801944 ITGB1/SLC3A2/SLC43A2/SLC1A5/ARL6IP5 5 GO:0097178 ruffle assembly 5/742 44/18722 0.0292682246903871 0.139038233801944 KANK1/CAV1/TACSTD2/PFN1/EPS8L1 5 GO:0071900 regulation of protein serine/threonine kinase activity 22/742 359/18722 0.0292712071161987 0.139038233801944 EGFR/CCNL1/ERP29/DUSP1/CAV1/IQGAP1/FLT1/LRP5/BMP7/ATP2B4/NR2F2/SERTAD1/NF1/MAGED1/AKAP13/CALM1/RHOA/IGF2/CALM2/CKS1B/PDCD4/CCNE1 22 GO:1903312 negative regulation of mRNA metabolic process 8/742 92/18722 0.0294838552086607 0.139483467961463 FUS/NPM1/YBX1/SRSF7/SRSF6/LARP1/CIRBP/HNRNPC 8 GO:0006884 cell volume homeostasis 4/742 30/18722 0.0295908247821078 0.139483467961463 KCNN4/SLC12A9/NPM1/CLN3 4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation 4/742 30/18722 0.0295908247821078 0.139483467961463 APP/BMP7/CALM1/CALM2 4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 4/742 30/18722 0.0295908247821078 0.139483467961463 CTSL/CTSD/CTSV/LGMN 4 GO:0060218 hematopoietic stem cell differentiation 4/742 30/18722 0.0295908247821078 0.139483467961463 N4BP2L2/UFL1/PRKDC/CHD2 4 GO:0060674 placenta blood vessel development 4/742 30/18722 0.0295908247821078 0.139483467961463 SPINT1/NR2F2/JUNB/HES1 4 GO:1900101 regulation of endoplasmic reticulum unfolded protein response 4/742 30/18722 0.0295908247821078 0.139483467961463 HSPA5/UFL1/PPP1R15A/ATF6 4 GO:2000648 positive regulation of stem cell proliferation 4/742 30/18722 0.0295908247821078 0.139483467961463 N4BP2L2/GJA1/LTBP3/CCNE1 4 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 15/742 221/18722 0.0304055292481446 0.143187144409756 CTSC/UFL1/CAV1/RPL23/TMEM259/HSPA1A/HSPA1B/HECTD1/EIF3H/GNA12/GPX1/BCAP31/DDA1/PSME2/SDCBP 15 GO:0009895 negative regulation of catabolic process 20/742 320/18722 0.0305363874512602 0.143666432389739 EGFR/MET/MYCBP2/FUS/RPL23/ATP2B4/CTSA/EIF4G1/YBX1/ROCK1/CST3/TIMP3/NCOR1/EIF3H/DHX36/LARP1/CIRBP/HNRNPC/ATRAID/SDCBP 20 GO:0090087 regulation of peptide transport 14/742 202/18722 0.0306407062345596 0.143936653391197 EGFR/LRP1/SOX4/GJA1/DPP4/DYNLL1/LRP5/ISL1/KIF5B/TCF7L2/SYT7/SLC16A1/HMGN3/PHPT1 14 GO:0003014 renal system process 9/742 110/18722 0.030681234012334 0.143936653391197 CLDN4/GJA1/MAGED2/GJA5/LGMN/ADM/ATP6V1B1/CLN3/RHOA 9 GO:0014812 muscle cell migration 9/742 110/18722 0.030681234012334 0.143936653391197 LRP1/IQGAP1/SEMA6D/ADAMTS1/NRP1/ANXA1/ROCK1/GNA12/RHOA 9 GO:0071426 ribonucleoprotein complex export from nucleus 7/742 76/18722 0.0307824696496545 0.144274573120771 NPM1/TPR/PABPN1/UPF2/THOC2/RAN/SSB 7 GO:0030071 regulation of mitotic metaphase/anaphase transition 6/742 60/18722 0.0310432449824118 0.145291136525722 DUSP1/TPR/NEK6/ANAPC11/UBE2C/LCMT1 6 GO:0035303 regulation of dephosphorylation 10/742 128/18722 0.031058186269466 0.145291136525722 HSP90B1/SLC39A10/BOD1L1/PPP1R15A/ROCK1/PPIA/CALM1/CALM2/CSNK2B/YWHAE 10 GO:1901796 regulation of signal transduction by p53 class mediator 8/742 93/18722 0.0311849097831794 0.145745935978151 RPS20/MIF/RPL26/RPL23/NPM1/PMAIP1/DDX5/EIF5A 8 GO:0072503 cellular divalent inorganic cation homeostasis 28/742 486/18722 0.0312433282515537 0.145880946656593 ATP2B1/HSP90B1/TPT1/LRP1/ITGAV/SLC39A10/APP/CAV1/GJA1/GSTO1/ATP2B4/CCDC47/CALR/S100A9/DIAPH1/SLC39A7/CD55/TMEM165/GTF2I/ADM/DDIT3/CALM1/CLN3/HEXB/BCAP31/TGM2/CALM2/YWHAE 28 GO:0042886 amide transport 19/742 301/18722 0.0315254865165174 0.14705939885892 LRP2/EGFR/LRP1/PSAP/SOX4/GJA1/SLC19A1/DPP4/DYNLL1/LRP5/ISL1/FOLR1/ANXA1/KIF5B/TCF7L2/SYT7/SLC16A1/HMGN3/PHPT1 19 GO:0006643 membrane lipid metabolic process 14/742 203/18722 0.0317640977305735 0.147510870212367 PSAP/HEXA/ORMDL1/HACD3/PLPP3/FUCA1/DEGS1/SERINC1/GPAA1/GLB1/PGAP1/SERINC3/ASAH1/HEXB 14 GO:0032869 cellular response to insulin stimulus 14/742 203/18722 0.0317640977305735 0.147510870212367 ATP2B1/KANK1/PRKDC/ZFP36L1/IGF1R/SRSF5/ESRRA/SLC9A1/PHIP/PTPRA/VAMP2/PKM/PARP1/IGF2 14 GO:0060541 respiratory system development 14/742 203/18722 0.0317640977305735 0.147510870212367 EGFR/LAMA5/DAG1/DLG5/MME/GLI3/LTBP3/MAN2A1/MAN1A2/SRSF6/EPAS1/HES1/PTGES3/CDC42 14 GO:0048659 smooth muscle cell proliferation 13/742 184/18722 0.0318190704136114 0.147510870212367 JUN/EGFR/SF1/GJA1/ADAMTS1/PRKDC/TCF7L2/FOXP1/GNA12/TGM2/RHOA/HPGD/PDCD4 13 GO:0055001 muscle cell development 13/742 184/18722 0.0318190704136114 0.147510870212367 KRT19/ITGB1/PLEC/KRT8/ISL1/ACTG1/AKAP13/ACTN4/ADM/OBSL1/GPX1/HES1/YY1 13 GO:2001257 regulation of cation channel activity 13/742 184/18722 0.0318190704136114 0.147510870212367 AHNAK/APP/ITGB1/CAV1/ANK3/GSTO1/TMSB4X/KIF5B/DLG1/STOM/VAMP2/CALM1/CALM2 13 GO:0030850 prostate gland development 5/742 45/18722 0.0318910140459125 0.147510870212367 PSAP/SERPINF1/BMP7/ANXA1/GLI3 5 GO:0035307 positive regulation of protein dephosphorylation 5/742 45/18722 0.0318910140459125 0.147510870212367 SLC39A10/PPP1R15A/PPIA/CALM1/CALM2 5 GO:0060119 inner ear receptor cell development 5/742 45/18722 0.0318910140459125 0.147510870212367 TRIP11/NAGLU/TRIOBP/IFT27/HES1 5 GO:0045765 regulation of angiogenesis 21/742 342/18722 0.032039203247567 0.148057683856858 GRN/ITGB1/SEMA6A/RHOB/SERPINF1/COL4A2/ADAMTS1/FLT1/NRP1/ATP2B4/ISL1/NF1/MYDGF/BTG1/ROCK1/EMC10/GTF2I/ADM/PKM/HSPB1/ANXA3 21 GO:0031330 negative regulation of cellular catabolic process 17/742 262/18722 0.0323400453511688 0.149118651255053 MET/FUS/RPL23/ATP2B4/CTSA/EIF4G1/YBX1/ROCK1/CST3/TIMP3/EIF3H/DHX36/LARP1/CIRBP/HNRNPC/ATRAID/SDCBP 17 GO:0036499 PERK-mediated unfolded protein response 3/742 18/18722 0.0324499089269598 0.149118651255053 HSPA5/PPP1R15A/DDIT3 3 GO:0048486 parasympathetic nervous system development 3/742 18/18722 0.0324499089269598 0.149118651255053 NRP2/NRP1/HES1 3 GO:0099558 maintenance of synapse structure 3/742 18/18722 0.0324499089269598 0.149118651255053 DLG1/ERC1/SDF4 3 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 3/742 18/18722 0.0324499089269598 0.149118651255053 ZFP36L1/TNRC6B/DHX36 3 GO:1901673 regulation of mitotic spindle assembly 3/742 18/18722 0.0324499089269598 0.149118651255053 TPR/HSPA1A/HSPA1B 3 GO:0071166 ribonucleoprotein complex localization 7/742 77/18722 0.0327499138437192 0.150030048165906 NPM1/TPR/PABPN1/UPF2/THOC2/RAN/SSB 7 GO:0030307 positive regulation of cell growth 12/742 166/18722 0.0328429747219526 0.150030048165906 EGFR/LRP1/GOLGA4/MACF1/NRP1/SLC9A1/EIF4G1/S100A9/CDC42/RHOA/RAB11A/SDCBP 12 GO:1902904 negative regulation of supramolecular fiber organization 12/742 166/18722 0.0328429747219526 0.150030048165906 MET/KANK1/SPTAN1/TACSTD2/PFN1/TMSB4X/SPTBN1/WASF2/TRIOBP/PPP1R9A/KANK4/CAPZB 12 GO:0006613 cotranslational protein targeting to membrane 4/742 31/18722 0.0329430758603481 0.150030048165906 SEC62/SIL1/SEC61A1/SEC63 4 GO:0007190 activation of adenylate cyclase activity 4/742 31/18722 0.0329430758603481 0.150030048165906 LGR5/LGR4/ADRB1/CALM1 4 GO:0030201 heparan sulfate proteoglycan metabolic process 4/742 31/18722 0.0329430758603481 0.150030048165906 EXTL2/GPC1/B3GAT3/TCF7L2 4 GO:0051443 positive regulation of ubiquitin-protein transferase activity 4/742 31/18722 0.0329430758603481 0.150030048165906 RPS2/SKP1/UBE2L3/UBE2C 4 GO:0071480 cellular response to gamma radiation 4/742 31/18722 0.0329430758603481 0.150030048165906 HSPA5/RPL26/EGR1/TMEM109 4 GO:0090183 regulation of kidney development 4/742 31/18722 0.0329430758603481 0.150030048165906 LGR4/TACSTD2/MAGED1/GATA3 4 GO:0030316 osteoclast differentiation 8/742 94/18722 0.0329519437773296 0.150030048165906 FBN1/FOS/TFRC/ATP6AP1/ESRRA/CD81/JUNB/FOXP1 8 GO:0040014 regulation of multicellular organism growth 6/742 61/18722 0.0333208164490054 0.15156982804612 APP/LGMN/ADRB1/NIPBL/CELF1/IGF2 6 GO:0051146 striated muscle cell differentiation 18/742 283/18722 0.0334530155267869 0.152031183718793 KRT19/ITGB1/PLEC/KRT8/ISL1/CALR/CD81/SLC9A1/ACTG1/PLD3/AKAP13/YBX1/OBSL1/GPX1/YY1/IGF2/MORF4L2/CACYBP 18 GO:0010212 response to ionizing radiation 11/742 148/18722 0.0336248241572749 0.152671536155274 HSPA5/RHOB/RPL26/EGR1/PRKDC/ANXA1/NIPBL/TMEM109/GATA3/GPX1/PARP1 11 GO:0032984 protein-containing complex disassembly 15/742 224/18722 0.0336739440487543 0.152754163086177 RPL23/SPTAN1/IGF1R/SPTBN1/KIF5B/ARID1A/TRIOBP/LAMP2/CFL1/CALM1/CLN3/DSTN/CAPZB/HMGA1/EIF5A 15 GO:0051028 mRNA transport 10/742 130/18722 0.0340392207872845 0.154269496045124 ZFP36L1/TPR/PABPN1/UPF2/RANBP2/HNRNPA1/SRSF7/THOC2/IGF2BP3/EIF5A 10 GO:0031331 positive regulation of cellular catabolic process 25/742 427/18722 0.0341522118241154 0.154566160833983 LRP2/LRP1/APP/CTSC/KCNQ1OT1/UFL1/CAV1/ZFP36L1/TMEM59/TNRC6A/TMEM259/HSPA1A/CD81/TNRC6B/HSPA1B/ROCK1/PUM1/HECTD1/ATF6/DHX36/CELF1/LARP1/VDAC1/BCAP31/DDA1 25 GO:0034767 positive regulation of ion transmembrane transport 12/742 167/18722 0.0341672566054069 0.154566160833983 AKAP9/TCAF1/ITGB1/KCNN4/ANK3/GSTO1/TMSB4X/SLC9A1/KIF5B/ACTN4/CALM1/CALM2 12 GO:0022407 regulation of cell-cell adhesion 26/742 448/18722 0.0342244549121271 0.154683263738251 CD46/CDH1/TENM3/SPINT2/TFRC/CAV1/SOX4/IL6ST/PLPP3/DPP4/ANK3/DLG5/BMP7/MIA3/NFAT5/CD81/ANXA1/GLI3/DLG1/CD55/CITED2/GATA3/DOCK8/HES1/RHOA/IGF2 26 GO:0050727 regulation of inflammatory response 23/742 386/18722 0.0346024460271122 0.155997797085447 EGFR/NEAT1/GRN/APP/CTSC/SERPINF1/UFL1/IL6ST/ISL1/BRD4/TMSB4X/CD81/ANXA1/S100A9/ASH1L/FOXP1/CELF1/NFKBIA/GATA3/GPX1/TGM2/GPX4/PDCD4 23 GO:0045851 pH reduction 5/742 46/18722 0.0346560920624579 0.155997797085447 GRN/ATP6AP1/ATP6AP2/ATP6V1B1/CLN3 5 GO:0061462 protein localization to lysosome 5/742 46/18722 0.0346560920624579 0.155997797085447 RTN4/GCC2/CD81/LAMP2/GNPTAB 5 GO:0072599 establishment of protein localization to endoplasmic reticulum 5/742 46/18722 0.0346560920624579 0.155997797085447 HSPA5/SEC62/SEC61A1/SEC63/SPCS2 5 GO:0030516 regulation of axon extension 8/742 95/18722 0.0347859242586866 0.155997797085447 LRP1/GOLGA4/SEMA6A/MACF1/SEMA6D/RTN4/NRP1/RAB11A 8 GO:0036473 cell death in response to oxidative stress 8/742 95/18722 0.0347859242586866 0.155997797085447 P4HB/MET/ARL6IP5/PPIA/TXN/HSPB1/GPX1/PARP1 8 GO:1901379 regulation of potassium ion transmembrane transport 8/742 95/18722 0.0347859242586866 0.155997797085447 AKAP9/ITGB1/KCNN4/CAV1/ANK3/DLG1/VAMP2/YWHAE 8 GO:0008306 associative learning 7/742 78/18722 0.0347995085805997 0.155997797085447 FOS/APP/ITGB1/LGMN/NF1/TPBG/CLN3 7 GO:0090559 regulation of membrane permeability 7/742 78/18722 0.0347995085805997 0.155997797085447 JAM3/HSPA1A/SLC9A1/PMAIP1/NMT1/VDAC2/DYNLT1 7 GO:0016482 cytosolic transport 12/742 168/18722 0.0355291430288672 0.158185859708408 TMEM87A/EEA1/GCC2/HOOK2/VPS13C/KIF5B/SYT7/ERC1/LAMP1/CLTC/CLN3/RHOBTB3 12 GO:1902806 regulation of cell cycle G1/S phase transition 12/742 168/18722 0.0355291430288672 0.158185859708408 EGFR/SOX4/RPL26/ADAMTS1/PRKDC/ATP2B4/ANXA1/EIF4G1/DLG1/CTDSPL/BRD7/PSME2 12 GO:0061136 regulation of proteasomal protein catabolic process 13/742 187/18722 0.0355773355922907 0.158185859708408 UFL1/CAV1/TMEM259/HSPA1A/HSPA1B/HECTD1/EIF3H/GNA12/GPX1/BCAP31/DDA1/PSME2/SDCBP 13 GO:0031623 receptor internalization 9/742 113/18722 0.0356001993633508 0.158185859708408 LRP1/ITGB1/LRPAP1/TFRC/CAV1/CD81/ADM/CLTC/SDCBP 9 GO:0006612 protein targeting to membrane 10/742 131/18722 0.035602284174426 0.158185859708408 HSPA5/TCAF1/SEC62/NACA/SIL1/ANK3/STOM/SEC61A1/SEC63/SDCBP 10 GO:0009896 positive regulation of catabolic process 28/742 492/18722 0.0356907003199066 0.158185859708408 LRP2/LRP1/APP/CTSC/KCNQ1OT1/UFL1/CAV1/GJA1/ZFP36L1/TMEM59/TNRC6A/TMEM259/HSPA1A/CD81/DDB1/TNRC6B/HSPA1B/ROCK1/PUM1/HECTD1/ATF6/DHX36/CELF1/LARP1/HUWE1/VDAC1/BCAP31/DDA1 28 GO:0007091 metaphase/anaphase transition of mitotic cell cycle 6/742 62/18722 0.0357038934362095 0.158185859708408 DUSP1/TPR/NEK6/ANAPC11/UBE2C/LCMT1 6 GO:0032835 glomerulus development 6/742 62/18722 0.0357038934362095 0.158185859708408 ENPEP/IQGAP1/LGR4/EGR1/BMP7/HES1 6 GO:0046824 positive regulation of nucleocytoplasmic transport 6/742 62/18722 0.0357038934362095 0.158185859708408 CDH1/TPR/GLI3/TCF7L2/RAN/YWHAE 6 GO:0046847 filopodium assembly 6/742 62/18722 0.0357038934362095 0.158185859708408 ITGB4/NRP1/PPP1R9A/CLN3/CDC42/CAPZB 6 GO:0048488 synaptic vesicle endocytosis 6/742 62/18722 0.0357038934362095 0.158185859708408 ACTG1/CANX/KIAA1109/ROCK1/VAMP2/CALM1 6 GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 6/742 62/18722 0.0357038934362095 0.158185859708408 DAG1/CTNND1/DLG1/VAMP2/RAB11A/YWHAE 6 GO:0140238 presynaptic endocytosis 6/742 62/18722 0.0357038934362095 0.158185859708408 ACTG1/CANX/KIAA1109/ROCK1/VAMP2/CALM1 6 GO:0014044 Schwann cell development 4/742 32/18722 0.0365079540519854 0.160595986657888 ITGB4/DAG1/PLEC/NF1 4 GO:0021799 cerebral cortex radially oriented cell migration 4/742 32/18722 0.0365079540519854 0.160595986657888 ADGRG1/LAMB1/RTN4/GLI3 4 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 4/742 32/18722 0.0365079540519854 0.160595986657888 TGFBR3/FERMT1/CITED2/SDCBP 4 GO:0050685 positive regulation of mRNA processing 4/742 32/18722 0.0365079540519854 0.160595986657888 TRA2B/DHX36/CIRBP/PRDX6 4 GO:0060323 head morphogenesis 4/742 32/18722 0.0365079540519854 0.160595986657888 ANKRD11/ATP6AP2/NIPBL/ARID5B 4 GO:0060914 heart formation 4/742 32/18722 0.0365079540519854 0.160595986657888 LRP2/ISL1/FOLR1/HES1 4 GO:1901532 regulation of hematopoietic progenitor cell differentiation 4/742 32/18722 0.0365079540519854 0.160595986657888 N4BP2L2/PRKDC/DHX36/HES1 4 GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 4/742 32/18722 0.0365079540519854 0.160595986657888 TGFBR3/FERMT1/CITED2/SDCBP 4 GO:0044264 cellular polysaccharide metabolic process 8/742 96/18722 0.0366877726334355 0.161243413531291 GAA/IL6ST/AGL/RB1CC1/PTGES3/IGF2/PYGL/UGP2 8 GO:0030011 maintenance of cell polarity 3/742 19/18722 0.0374290717807835 0.162496594169556 DLG5/DST/SLC9A1 3 GO:0031290 retinal ganglion cell axon guidance 3/742 19/18722 0.0374290717807835 0.162496594169556 RPL24/NRP1/ISL1 3 GO:0045019 negative regulation of nitric oxide biosynthetic process 3/742 19/18722 0.0374290717807835 0.162496594169556 CAV1/DYNLL1/ATP2B4 3 GO:0046794 transport of virus 3/742 19/18722 0.0374290717807835 0.162496594169556 CTSL/CAV1/DYNLT1 3 GO:0070262 peptidyl-serine dephosphorylation 3/742 19/18722 0.0374290717807835 0.162496594169556 DUSP1/PPP1R15A/YWHAE 3 GO:1900221 regulation of amyloid-beta clearance 3/742 19/18722 0.0374290717807835 0.162496594169556 LRP1/LRPAP1/ROCK1 3 GO:1904406 negative regulation of nitric oxide metabolic process 3/742 19/18722 0.0374290717807835 0.162496594169556 CAV1/DYNLL1/ATP2B4 3 GO:2000738 positive regulation of stem cell differentiation 3/742 19/18722 0.0374290717807835 0.162496594169556 TACSTD2/LTBP3/DHX36 3 GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 5/742 47/18722 0.0375650021339337 0.162496594169556 ENPEP/MME/ATP6AP2/ADRB1/RHOA 5 GO:0010761 fibroblast migration 5/742 47/18722 0.0375650021339337 0.162496594169556 ITGB1/PLEC/ARID5B/GNA12/CLN3 5 GO:0010799 regulation of peptidyl-threonine phosphorylation 5/742 47/18722 0.0375650021339337 0.162496594169556 APP/BMP7/EIF4G1/CALM1/CALM2 5 GO:0014911 positive regulation of smooth muscle cell migration 5/742 47/18722 0.0375650021339337 0.162496594169556 LRP1/IQGAP1/SEMA6D/ADAMTS1/NRP1 5 GO:0042311 vasodilation 5/742 47/18722 0.0375650021339337 0.162496594169556 EGFR/GJA1/GJA5/ADRB1/GPX1 5 GO:0045646 regulation of erythrocyte differentiation 5/742 47/18722 0.0375650021339337 0.162496594169556 PRKDC/ZFP36L1/HSPA1A/CDK6/HSPA1B 5 GO:0048512 circadian behavior 5/742 47/18722 0.0375650021339337 0.162496594169556 EGR1/ZFHX3/NAGLU/ADRB1/NCOR1 5 GO:0050885 neuromuscular process controlling balance 5/742 47/18722 0.0375650021339337 0.162496594169556 APP/GAA/IGDCC3/CLN3/HEXB 5 GO:0051489 regulation of filopodium assembly 5/742 47/18722 0.0375650021339337 0.162496594169556 NRP1/PPP1R9A/CLN3/CDC42/CAPZB 5 GO:1900744 regulation of p38MAPK cascade 5/742 47/18722 0.0375650021339337 0.162496594169556 GADD45B/DUSP1/DLG1/EMC10/GADD45G 5 GO:0050900 leukocyte migration 22/742 369/18722 0.0379303594400435 0.163933486993714 CSF3R/APP/ITGB1/PLEC/BSG/DUSP1/MIF/DPP4/FLT1/JAM3/CALR/MIA3/CD81/ANXA1/LGMN/S100A9/ROCK1/PPIA/GATA3/DOCK8/CDC42/RHOA 22 GO:0071456 cellular response to hypoxia 11/742 151/18722 0.0380702988713635 0.16406716061404 MALAT1/P4HB/EGR1/ZFP36L1/BMP7/SLC9A1/ENO1/PMAIP1/HP1BP3/CITED2/EPAS1 11 GO:0022617 extracellular matrix disassembly 6/742 63/18722 0.0381937722077219 0.16406716061404 LRP1/LAMC1/CTSV/DPP4/MMP15/CST3 6 GO:0032233 positive regulation of actin filament bundle assembly 6/742 63/18722 0.0381937722077219 0.16406716061404 NRP1/PFN1/ID1/S100A10/CDC42/RHOA 6 GO:0046902 regulation of mitochondrial membrane permeability 6/742 63/18722 0.0381937722077219 0.16406716061404 HSPA1A/SLC9A1/PMAIP1/NMT1/VDAC2/DYNLT1 6 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 6/742 63/18722 0.0381937722077219 0.16406716061404 ERP29/PPP1R15A/HSPA1A/PMAIP1/SERINC3/DDIT3 6 GO:1902099 regulation of metaphase/anaphase transition of cell cycle 6/742 63/18722 0.0381937722077219 0.16406716061404 DUSP1/TPR/NEK6/ANAPC11/UBE2C/LCMT1 6 GO:2000242 negative regulation of reproductive process 6/742 63/18722 0.0381937722077219 0.16406716061404 SERPINF1/DUSP1/GJA1/BMP7/CALR/PRDX4 6 GO:0031667 response to nutrient levels 27/742 474/18722 0.0382521026453881 0.164174967044498 JUN/EGFR/ATP2B1/HSPA5/SLC2A1/LDHA/PLEC/SLC38A2/CTSV/SLC6A4/CSH1/AGL/BMP7/POR/TNRC6A/FOLR1/EIF4G1/PMAIP1/ADRB1/HNRNPA1/LAMP2/ADM/DDIT3/EIF2AK4/LARP1/KRT18/SLC16A1 27 GO:0120162 positive regulation of cold-induced thermogenesis 8/742 97/18722 0.0386583632344781 0.165774578453405 DYNC1H1/CAV1/GJA1/IGF1R/PRLR/ADRB1/EPAS1/GADD45G 8 GO:0051348 negative regulation of transferase activity 17/742 268/18722 0.0387970345549181 0.166224935560534 RPS20/PLEC/GADD45B/DUSP1/CAV1/RPL23/LRP5/NPM1/BMP7/NR2F2/NF1/GNAQ/PPIA/HSPB1/ADAR/PHPT1/PDCD4 17 GO:0046887 positive regulation of hormone secretion 10/742 133/18722 0.0388767003669731 0.166421923581323 EGFR/LRP1/SOX4/GJA1/DYNLL1/ISL1/KIF5B/TCF7L2/PHPT1/CYP19A1 10 GO:0030278 regulation of ossification 9/742 115/18722 0.039164816092549 0.167365217558125 FBN2/ATP2B1/PBX1/BMP7/ESRRA/LTBP3/NIPBL/NOTUM/ATRAID 9 GO:0034968 histone lysine methylation 9/742 115/18722 0.039164816092549 0.167365217558125 ATRX/BRD4/KMT2C/ASH1L/TET2/NSD1/RIF1/RTF1/GATA3 9 GO:0030509 BMP signaling pathway 11/742 152/18722 0.0396391631481797 0.168969486826949 LRP2/FBN1/CRIM1/TGFBR3/EGR1/BMP7/FSTL1/USP9X/DDX5/HES1/PDCD4 11 GO:0031056 regulation of histone modification 11/742 152/18722 0.0396391631481797 0.168969486826949 ATRX/ISL1/BRD4/KDM5A/NIPBL/NSD1/RIF1/BRD7/RTF1/GATA3/IGF2 11 GO:0099111 microtubule-based transport 13/742 190/18722 0.0396428411401688 0.168969486826949 ARMCX3/APP/DYNC1H1/DST/ARHGAP21/KIF5B/PURA/IFT27/LAMP1/PCM1/HSPB1/CLN3/CDC42 13 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 16/742 249/18722 0.03993248872285 0.169910847795762 GAPDH/UFL1/TFRC/WLS/GJA1/BRD4/TMED4/ASH1L/AKAP13/SLC44A2/DHX36/HSPB1/USP10/TGM2/NEK6/RHOA 16 GO:0045926 negative regulation of growth 16/742 249/18722 0.03993248872285 0.169910847795762 SEMA6A/SEMA6D/GJA1/SLC6A4/RTN4/NRP1/HSPA1A/ENO1/LGMN/BTG1/ADRB1/HSPA1B/SMARCA2/CITED2/YY1/CGA 16 GO:0003382 epithelial cell morphogenesis 4/742 33/18722 0.0402862868972849 0.170681181194329 MET/SPINT2/FAT1/ST14 4 GO:0060122 inner ear receptor cell stereocilium organization 4/742 33/18722 0.0402862868972849 0.170681181194329 TRIP11/TRIOBP/IFT27/HES1 4 GO:0150117 positive regulation of cell-substrate junction organization 4/742 33/18722 0.0402862868972849 0.170681181194329 IQGAP1/NRP1/ROCK1/S100A10 4 GO:1901976 regulation of cell cycle checkpoint 4/742 33/18722 0.0402862868972849 0.170681181194329 DUSP1/PPP1R10/TPR/LCMT1 4 GO:2000036 regulation of stem cell population maintenance 4/742 33/18722 0.0402862868972849 0.170681181194329 ZC3H13/BMP7/NCOA3/LBH 4 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 10/742 134/18722 0.0405892655774699 0.171502574420287 UFL1/CAV1/HSPA1A/HSPA1B/HECTD1/EIF3H/GNA12/BCAP31/DDA1/SDCBP 10 GO:0061041 regulation of wound healing 10/742 134/18722 0.0405892655774699 0.171502574420287 ITGB1/CLDN4/KANK1/CAV1/GJA1/PLPP3/FERMT1/ANXA1/ACTG1/SRSF6 10 GO:0035036 sperm-egg recognition 5/742 48/18722 0.0406190307837521 0.171502574420287 ALDOA/SPESP1/FOLR1/VDAC2/CCT3 5 GO:1905710 positive regulation of membrane permeability 5/742 48/18722 0.0406190307837521 0.171502574420287 JAM3/HSPA1A/SLC9A1/NMT1/VDAC2 5 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 8/742 98/18722 0.0406985220025591 0.171644450561352 TPT1/MIF/HSPA1A/ENO1/PPIA/HSPB1/GPX1/VDAC2 8 GO:0030104 water homeostasis 6/742 64/18722 0.0407916163884672 0.171644450561352 CLDN4/MET/PLEC/LSR/ATP6V1B1/CLN3 6 GO:0045995 regulation of embryonic development 6/742 64/18722 0.0407916163884672 0.171644450561352 LAMA5/DAG1/NIPBL/CFL1/DHX36/HES1 6 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 6/742 64/18722 0.0407916163884672 0.171644450561352 LRP1/DYNLL1/LRP5/KIF5B/HMGN3/PHPT1 6 GO:0033559 unsaturated fatty acid metabolic process 9/742 116/18722 0.0410348840347511 0.172521129473762 MIF/DEGS1/ANXA1/ATP6V1B1/GPX1/PTGES3/CYP2J2/GPX4/HPGD 9 GO:0001558 regulation of cell growth 24/742 414/18722 0.041124211386506 0.17274966347733 EGFR/LRP1/GOLGA4/SEMA6A/MACF1/SEMA6D/GJA1/RTN4/NRP1/NPM1/HSPA1A/SLC9A1/ENO1/EIF4G1/S100A9/BTG1/KIAA1109/HSPA1B/SMARCA2/YY1/CDC42/RHOA/RAB11A/SDCBP 24 GO:0007219 Notch signaling pathway 12/742 172/18722 0.0413620966369811 0.173601323183251 CD46/KRT19/APP/AAK1/GALNT11/IL6ST/BMP7/NCSTN/MAML2/NFKBIA/HES1/ANXA4 12 GO:0010833 telomere maintenance via telomere lengthening 7/742 81/18722 0.0414519629209528 0.173830812249157 HNRNPA1/DHX36/RAD50/PARP1/HNRNPC/PTGES3/CCT3 7 GO:0003215 cardiac right ventricle morphogenesis 3/742 20/18722 0.0427741342231588 0.177715915107153 SOX4/ISL1/GATA3 3 GO:0006590 thyroid hormone generation 3/742 20/18722 0.0427741342231588 0.177715915107153 CPQ/GATA3/CGA 3 GO:0006700 C21-steroid hormone biosynthetic process 3/742 20/18722 0.0427741342231588 0.177715915107153 EGR1/ADM/CYP11A1 3 GO:0010523 negative regulation of calcium ion transport into cytosol 3/742 20/18722 0.0427741342231588 0.177715915107153 GSTO1/CALM1/CALM2 3 GO:0010801 negative regulation of peptidyl-threonine phosphorylation 3/742 20/18722 0.0427741342231588 0.177715915107153 EIF4G1/CALM1/CALM2 3 GO:0010893 positive regulation of steroid biosynthetic process 3/742 20/18722 0.0427741342231588 0.177715915107153 POR/ADM/CGA 3 GO:0032986 protein-DNA complex disassembly 3/742 20/18722 0.0427741342231588 0.177715915107153 RPL23/ARID1A/HMGA1 3 GO:0042359 vitamin D metabolic process 3/742 20/18722 0.0427741342231588 0.177715915107153 LRP2/LGMN/CYP11A1 3 GO:0048025 negative regulation of mRNA splicing, via spliceosome 3/742 20/18722 0.0427741342231588 0.177715915107153 NPM1/SRSF7/SRSF6 3 GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 3/742 20/18722 0.0427741342231588 0.177715915107153 PPIA/HSPB1/GPX1 3 GO:1904292 regulation of ERAD pathway 3/742 20/18722 0.0427741342231588 0.177715915107153 CAV1/TMEM259/BCAP31 3 GO:0051225 spindle assembly 9/742 117/18722 0.0429643452710673 0.178356189612666 DYNC1H1/TPR/HSPA1A/HSPA1B/NCOR1/KPNB1/NEK6/RHOA/RAB11A 9 GO:0006469 negative regulation of protein kinase activity 14/742 212/18722 0.0432549840151518 0.179411940415491 PLEC/GADD45B/DUSP1/CAV1/LRP5/NPM1/BMP7/NR2F2/NF1/GNAQ/PPIA/HSPB1/ADAR/PDCD4 14 GO:0010965 regulation of mitotic sister chromatid separation 6/742 65/18722 0.0434984555123839 0.179430220825333 DUSP1/TPR/NEK6/ANAPC11/UBE2C/LCMT1 6 GO:0035418 protein localization to synapse 6/742 65/18722 0.0434984555123839 0.179430220825333 DAG1/KIF5B/DLG1/VAMP2/HSPB1/RAB11A 6 GO:0043489 RNA stabilization 6/742 65/18722 0.0434984555123839 0.179430220825333 FUS/YBX1/DHX36/LARP1/CIRBP/HNRNPC 6 GO:0044784 metaphase/anaphase transition of cell cycle 6/742 65/18722 0.0434984555123839 0.179430220825333 DUSP1/TPR/NEK6/ANAPC11/UBE2C/LCMT1 6 GO:0090307 mitotic spindle assembly 6/742 65/18722 0.0434984555123839 0.179430220825333 TPR/HSPA1A/HSPA1B/KPNB1/RHOA/RAB11A 6 GO:0006692 prostanoid metabolic process 5/742 49/18722 0.0438192086815657 0.179430220825333 MIF/ANXA1/ATP6V1B1/PTGES3/HPGD 5 GO:0006693 prostaglandin metabolic process 5/742 49/18722 0.0438192086815657 0.179430220825333 MIF/ANXA1/ATP6V1B1/PTGES3/HPGD 5 GO:0007622 rhythmic behavior 5/742 49/18722 0.0438192086815657 0.179430220825333 EGR1/ZFHX3/NAGLU/ADRB1/NCOR1 5 GO:0035088 establishment or maintenance of apical/basal cell polarity 5/742 49/18722 0.0438192086815657 0.179430220825333 DLG5/FAT1/DLG1/CDC42/RHOA 5 GO:0038084 vascular endothelial growth factor signaling pathway 5/742 49/18722 0.0438192086815657 0.179430220825333 NRP2/SEMA6A/FLT1/NRP1/HSPB1 5 GO:0043330 response to exogenous dsRNA 5/742 49/18722 0.0438192086815657 0.179430220825333 CAV1/SLC3A2/COLEC12/DHX36/NFKBIA 5 GO:0045778 positive regulation of ossification 5/742 49/18722 0.0438192086815657 0.179430220825333 FBN2/ATP2B1/BMP7/NIPBL/ATRAID 5 GO:0061245 establishment or maintenance of bipolar cell polarity 5/742 49/18722 0.0438192086815657 0.179430220825333 DLG5/FAT1/DLG1/CDC42/RHOA 5 GO:0086009 membrane repolarization 5/742 49/18722 0.0438192086815657 0.179430220825333 AKAP9/CAV1/GJA5/ATP1A1/YWHAE 5 GO:1904752 regulation of vascular associated smooth muscle cell migration 5/742 49/18722 0.0438192086815657 0.179430220825333 LRP1/IQGAP1/ADAMTS1/GNA12/RHOA 5 GO:0009205 purine ribonucleoside triphosphate metabolic process 7/742 82/18722 0.0438405418089427 0.179430220825333 ALDOA/TMSB4X/ENO1/NME3/PARP1/RAN/RHOA 7 GO:0098876 vesicle-mediated transport to the plasma membrane 10/742 136/18722 0.0441679662207241 0.179880725330726 GOLGA4/MACF1/ANK3/SPTBN1/KIAA1109/VAMP2/CMTM6/KRT18/CLN3/RAB11A 10 GO:0001662 behavioral fear response 4/742 34/18722 0.0442783323891019 0.179880725330726 GJA1/DPP4/EIF4G1/VDAC1 4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 4/742 34/18722 0.0442783323891019 0.179880725330726 CTSL/CTSD/CTSV/LGMN 4 GO:0010922 positive regulation of phosphatase activity 4/742 34/18722 0.0442783323891019 0.179880725330726 SLC39A10/PPP1R15A/CALM1/CALM2 4 GO:0019320 hexose catabolic process 4/742 34/18722 0.0442783323891019 0.179880725330726 LRP5/ENO1/GLB1/FUT8 4 GO:0035308 negative regulation of protein dephosphorylation 4/742 34/18722 0.0442783323891019 0.179880725330726 BOD1L1/PPP1R15A/ROCK1/YWHAE 4 GO:0098751 bone cell development 4/742 34/18722 0.0442783323891019 0.179880725330726 FBN1/ATP6AP1/WASF2/FOXP1 4 GO:1990000 amyloid fibril formation 4/742 34/18722 0.0442783323891019 0.179880725330726 APP/USP9X/SIAH2/SIAH1 4 GO:2000758 positive regulation of peptidyl-lysine acetylation 4/742 34/18722 0.0442783323891019 0.179880725330726 SOX4/ISL1/BRD7/GATA3 4 GO:0062012 regulation of small molecule metabolic process 20/742 334/18722 0.044490677116108 0.180594860274095 APP/CAV1/EGR1/ATP2B4/POR/TMSB4X/ANXA1/ENO1/DDB1/PMAIP1/RANBP2/NCOR1/MBTPS1/ACADVL/ADM/SLC35B4/PARP1/CLN3/IGF2/LCMT1 20 GO:0006665 sphingolipid metabolic process 11/742 155/18722 0.0446139511888082 0.180798128689674 PSAP/HEXA/ORMDL1/HACD3/PLPP3/DEGS1/SERINC1/GLB1/SERINC3/ASAH1/HEXB 11 GO:1903364 positive regulation of cellular protein catabolic process 11/742 155/18722 0.0446139511888082 0.180798128689674 LRP2/LRP1/CTSC/CAV1/TMEM259/HSPA1A/CD81/HSPA1B/HECTD1/BCAP31/DDA1 11 GO:0055074 calcium ion homeostasis 26/742 460/18722 0.0447483033595246 0.181193949668895 ATP2B1/HSP90B1/TPT1/LRP1/ITGAV/APP/CAV1/GJA1/GSTO1/ATP2B4/CCDC47/CALR/DIAPH1/CD55/TMEM165/GTF2I/ADM/DDIT3/ATP6V1B1/CALM1/CLN3/HEXB/BCAP31/TGM2/CALM2/YWHAE 26 GO:0000280 nuclear division 25/742 439/18722 0.0449522020310767 0.18187049797995 RPL24/DUSP1/ATRX/LRP5/BMP7/TPR/CALR/HSPA1A/PHIP/NIPBL/HSPA1B/RAD50/OBSL1/KPNB1/RAN/CDC42/NEK6/RHOA/IGF2/RAB11A/ANAPC11/UBE2C/RANBP1/LCMT1/CCNE1 25 GO:0051090 regulation of DNA-binding transcription factor activity 25/742 440/18722 0.0459537464894745 0.185770464531918 APP/UFL1/TFRC/CAV1/PLPP3/LRP5/NPM1/BMP7/TMSB4X/HSPA1A/S100A9/KDM5A/HSPA1B/TCF7L2/PURA/ERC1/PPIA/DDIT3/ARID5B/EIF2AK4/NFKBIA/ID1/HES1/ANXA4/ANXA3 25 GO:0030879 mammary gland development 10/742 137/18722 0.0460351711285402 0.185795543607017 CAV1/RTN4/LRP5/PRLR/GLI3/KDM5B/ARHGAP5/GATA3/GPX1/LBH 10 GO:0050671 positive regulation of lymphocyte proliferation 10/742 137/18722 0.0460351711285402 0.185795543607017 CD46/SLC39A10/TFRC/MIF/IL6ST/CD81/ANXA1/CD55/HES1/IGF2 10 GO:0050954 sensory perception of mechanical stimulus 12/742 175/18722 0.0461538066639471 0.18612228973053 LRP2/NIPBL/DIAPH1/PGAP1/TRIOBP/SLC52A3/DDIT3/ATP6V1B1/NDUFB9/TBL1X/GPX1/HEXB 12 GO:0050922 negative regulation of chemotaxis 6/742 66/18722 0.0463151839575441 0.186472206025555 SEMA6A/DUSP1/MIF/SEMA6D/DPP4/NRP1 6 GO:0050886 endocrine process 7/742 83/18722 0.0463160722253758 0.186472206025555 ENPEP/GJA1/MME/ATP6AP2/GATA3/RHOA/CGA 7 GO:0060560 developmental growth involved in morphogenesis 15/742 234/18722 0.0464133296904845 0.186711603152275 NRP2/LRP1/APP/ITGB1/GOLGA4/SEMA6A/MACF1/IQGAP1/SEMA6D/RTN4/NRP1/USP9X/EIF2AK4/KDM5B/RAB11A 15 GO:0031398 positive regulation of protein ubiquitination 9/742 119/18722 0.0470039018996164 0.188933503160378 HSPA5/MYCBP2/CAV1/RPS2/NPM1/HUWE1/SKP1/UBE2L3/UBE2C 9 GO:0060688 regulation of morphogenesis of a branching structure 5/742 50/18722 0.0471663125189353 0.188971276434339 LGR4/RTN4/BMP7/TACSTD2/MAGED1 5 GO:1903747 regulation of establishment of protein localization to mitochondrion 5/742 50/18722 0.0471663125189353 0.188971276434339 LMAN1/NMT1/HUWE1/LEPROT/UBE2L3 5 GO:1904738 vascular associated smooth muscle cell migration 5/742 50/18722 0.0471663125189353 0.188971276434339 LRP1/IQGAP1/ADAMTS1/GNA12/RHOA 5 GO:2000677 regulation of transcription regulatory region DNA binding 5/742 50/18722 0.0471663125189353 0.188971276434339 TMSB4X/NSD1/DDIT3/GATA3/PARP1 5 GO:0042102 positive regulation of T cell proliferation 8/742 101/18722 0.0472439157827124 0.189128803862722 CD46/TFRC/IL6ST/CD81/ANXA1/CD55/HES1/IGF2 8 GO:0043270 positive regulation of ion transport 17/742 275/18722 0.0474558768590018 0.189823507436007 AKAP9/ATP2B1/TCAF1/ITGB1/KCNN4/CAV1/SLC6A4/ANK3/GSTO1/TMSB4X/PRSS8/SLC9A1/KIF5B/DLG1/ACTN4/CALM1/CALM2 17 GO:0007611 learning or memory 16/742 255/18722 0.0477625020823444 0.190087280878099 JUN/EGFR/FOS/APP/ITGB1/SERPINF1/SLC6A4/ARL6IP5/MME/LGMN/NF1/NCSTN/TPBG/EIF2AK4/VDAC1/CLN3 16 GO:0032946 positive regulation of mononuclear cell proliferation 10/742 138/18722 0.0479549500425821 0.190087280878099 CD46/SLC39A10/TFRC/MIF/IL6ST/CD81/ANXA1/CD55/HES1/IGF2 10 GO:0035107 appendage morphogenesis 10/742 138/18722 0.0479549500425821 0.190087280878099 FBN2/ATRX/SOX4/PBX1/LRP5/FRAS1/BMP7/GLI3/NIPBL/TMEM107 10 GO:0035108 limb morphogenesis 10/742 138/18722 0.0479549500425821 0.190087280878099 FBN2/ATRX/SOX4/PBX1/LRP5/FRAS1/BMP7/GLI3/NIPBL/TMEM107 10 GO:1902107 positive regulation of leukocyte differentiation 11/742 157/18722 0.0481586289984621 0.190087280878099 JUN/FOS/CD46/SOX4/PRKDC/ZFP36L1/ATP6AP1/ANXA1/GLI3/GATA3/RHOA 11 GO:1903708 positive regulation of hemopoiesis 11/742 157/18722 0.0481586289984621 0.190087280878099 JUN/FOS/CD46/SOX4/PRKDC/ZFP36L1/ATP6AP1/ANXA1/GLI3/GATA3/RHOA 11 GO:1990845 adaptive thermogenesis 11/742 157/18722 0.0481586289984621 0.190087280878099 DYNC1H1/CAV1/LGR4/GJA1/IGF1R/PRLR/ADRB1/DDIT3/EPAS1/ID1/GADD45G 11 GO:0050890 cognition 18/742 296/18722 0.0482575095072027 0.190087280878099 JUN/EGFR/FOS/APP/ITGB1/SERPINF1/SLC6A4/ARL6IP5/MME/LGMN/NF1/NCSTN/NIPBL/TUSC3/TPBG/EIF2AK4/VDAC1/CLN3 18 GO:0002689 negative regulation of leukocyte chemotaxis 3/742 21/18722 0.048478417582775 0.190087280878099 DUSP1/MIF/DPP4 3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen 3/742 21/18722 0.048478417582775 0.190087280878099 COX6A1/COX8C/COX5A 3 GO:0008090 retrograde axonal transport 3/742 21/18722 0.048478417582775 0.190087280878099 DYNC1H1/DST/KIF5B 3 GO:0035455 response to interferon-alpha 3/742 21/18722 0.048478417582775 0.190087280878099 TPR/GATA3/ADAR 3 GO:0044766 multi-organism transport 3/742 21/18722 0.048478417582775 0.190087280878099 CTSL/CAV1/DYNLT1 3 GO:0046514 ceramide catabolic process 3/742 21/18722 0.048478417582775 0.190087280878099 HEXA/ASAH1/HEXB 3 GO:0046823 negative regulation of nucleocytoplasmic transport 3/742 21/18722 0.048478417582775 0.190087280878099 TPR/FERMT1/TXN 3 GO:0072111 cell proliferation involved in kidney development 3/742 21/18722 0.048478417582775 0.190087280878099 EGR1/BMP7/GATA3 3 GO:0090189 regulation of branching involved in ureteric bud morphogenesis 3/742 21/18722 0.048478417582775 0.190087280878099 LGR4/TACSTD2/MAGED1 3 GO:1902579 multi-organism localization 3/742 21/18722 0.048478417582775 0.190087280878099 CTSL/CAV1/DYNLT1 3 GO:2001014 regulation of skeletal muscle cell differentiation 3/742 21/18722 0.048478417582775 0.190087280878099 GPC1/DDX17/DDX5 3 GO:0002209 behavioral defense response 4/742 35/18722 0.0484838003859118 0.190087280878099 GJA1/DPP4/EIF4G1/VDAC1 4 GO:0032205 negative regulation of telomere maintenance 4/742 35/18722 0.0484838003859118 0.190087280878099 HNRNPA1/RAD50/PARP1/HNRNPC 4 GO:0033146 regulation of intracellular estrogen receptor signaling pathway 4/742 35/18722 0.0484838003859118 0.190087280878099 UFL1/ISL1/PARP1/LBH 4 GO:0034405 response to fluid shear stress 4/742 35/18722 0.0484838003859118 0.190087280878099 PLEC/GJA1/CITED2/TFPI2 4 GO:0039694 viral RNA genome replication 4/742 35/18722 0.0484838003859118 0.190087280878099 EEA1/MPHOSPH8/PCBP2/CDC42 4 GO:0040001 establishment of mitotic spindle localization 4/742 35/18722 0.0484838003859118 0.190087280878099 ITGB1/GJA1/KPNB1/DYNLT1 4 GO:0010506 regulation of autophagy 19/742 317/18722 0.0488320836528378 0.191031346756442 GAPDH/EEF1A1/PSAP/MET/UFL1/CTSA/TMEM59/VPS13C/EIF4G1/ROCK1/ATF6/DDIT3/LARP1/ATP6V1B1/VDAC1/HSPB1/ATP6V0B/CLN3/USP10 19 GO:0006970 response to osmotic stress 7/742 84/18722 0.0488792757692597 0.191031346756442 EGFR/SLC2A1/ZFP36L1/NFAT5/MARVELD3/CLN3/EFHD1 7 GO:0032508 DNA duplex unwinding 7/742 84/18722 0.0488792757692597 0.191031346756442 ATRX/ANXA1/PURA/CHD2/DHX36/RAD50/HMGA1 7 GO:0061157 mRNA destabilization 7/742 84/18722 0.0488792757692597 0.191031346756442 ZFP36L1/TNRC6A/TNRC6B/ROCK1/PUM1/DHX36/CELF1 7 GO:0035914 skeletal muscle cell differentiation 6/742 67/18722 0.0492425602568755 0.191692866563408 FOS/EGR1/GPC1/DDX17/CITED2/DDX5 6 GO:0051306 mitotic sister chromatid separation 6/742 67/18722 0.0492425602568755 0.191692866563408 DUSP1/TPR/NEK6/ANAPC11/UBE2C/LCMT1 6 GO:0061180 mammary gland epithelium development 6/742 67/18722 0.0492425602568755 0.191692866563408 RTN4/LRP5/KDM5B/GATA3/GPX1/LBH 6 GO:0070527 platelet aggregation 6/742 67/18722 0.0492425602568755 0.191692866563408 IL6ST/ACTG1/PPIA/HSPB1/TLN1/MYL12A 6 GO:0072665 protein localization to vacuole 6/742 67/18722 0.0492425602568755 0.191692866563408 RTN4/GCC2/VPS13C/CD81/LAMP2/GNPTAB 6 GO:0030072 peptide hormone secretion 15/742 236/18722 0.0493202370730098 0.191844071764306 EGFR/LRP1/SOX4/GJA1/DPP4/DYNLL1/LRP5/ISL1/ANXA1/KIF5B/TCF7L2/SYT7/SLC16A1/HMGN3/PHPT1 15 GO:0051052 regulation of DNA metabolic process 21/742 359/18722 0.0494278412988577 0.192111357998707 EGFR/FUS/TFRC/DUSP1/ATRX/GJA1/PRKDC/PPP1R10/MPHOSPH8/NPM1/HNRNPA1/USP9X/DHX36/RIF1/RAD50/GATA3/PARP1/HNRNPC/PTGES3/ANXA3/CCT3 21 GO:0042594 response to starvation 13/742 197/18722 0.0503828548007898 0.195669263141432 JUN/HSPA5/SLC2A1/SLC38A2/CTSV/TNRC6A/PMAIP1/HNRNPA1/LAMP2/ADM/DDIT3/EIF2AK4/LARP1 13 GO:0021872 forebrain generation of neurons 5/742 51/18722 0.050660867684262 0.196440099183873 NRP2/NRP1/GLI3/HES1/RHOA 5 GO:0045104 intermediate filament cytoskeleton organization 5/742 51/18722 0.050660867684262 0.196440099183873 MACF1/PLEC/DSP/DST/KRT18 5 GO:0007596 blood coagulation 14/742 217/18722 0.0507734215549004 0.196722119593104 F5/FBLN1/LMAN1/CAV1/IL6ST/ANXA5/ACTG1/GNAQ/PPIA/GNA12/HSPB1/TFPI2/TLN1/MYL12A 14 GO:0042752 regulation of circadian rhythm 9/742 121/18722 0.0512880374981342 0.198353818621374 PRKDC/ZFHX3/DDB1/MAGED1/ADRB1/GNAQ/USP9X/NR2F6/SIAH2 9 GO:0035265 organ growth 12/742 178/18722 0.0513150162344363 0.198353818621374 PSAP/TGFBR3/GJA1/DUSP6/SLC6A4/POR/AKAP13/DUSP9/CITED2/YY1/IGF2/CGA 12 GO:0035725 sodium ion transmembrane transport 12/742 178/18722 0.0513150162344363 0.198353818621374 UTRN/SLC3A2/SLC6A4/ANK3/ATP2B4/SLC9A1/KIF5B/DLG1/STOM/ACTN4/ATP1A1/FXYD3 12 GO:0072384 organelle transport along microtubule 7/742 85/18722 0.0515307919547456 0.199032144062896 ARMCX3/DYNC1H1/ARHGAP21/KIF5B/LAMP1/CLN3/CDC42 7 GO:0051170 import into nucleus 11/742 159/18722 0.0518898230254922 0.200095845584877 CDH1/RPL23/PPP1R10/TPR/FERMT1/GLI3/RANBP2/HNRNPA1/NFKBIA/KPNB1/RAN 11 GO:0030177 positive regulation of Wnt signaling pathway 10/742 140/18722 0.051954086338238 0.200095845584877 EGFR/LGR5/MACF1/KANK1/WLS/CAV1/LGR4/SOX4/ATP6AP2/TBL1X 10 GO:0050768 negative regulation of neurogenesis 10/742 140/18722 0.051954086338238 0.200095845584877 SEMA6A/SEMA6D/RTN4/NRP1/BMP7/NF1/PCM1/ID1/HES1/DYNLT1 10 GO:0014013 regulation of gliogenesis 8/742 103/18722 0.0519682125274083 0.200095845584877 LRP2/EGFR/SPINT1/DAG1/UFL1/IL6ST/NF1/HES1 8 GO:0045165 cell fate commitment 16/742 258/18722 0.0520588035232167 0.20028854315007 CTSL/ITGB1/PRKDC/NRP1/LMO4/ISL1/NR2F2/GLI3/TCF7L2/IFRD1/RTF1/GATA3/EPAS1/HES1/CDC42/RHOA 16 GO:0051926 negative regulation of calcium ion transport 6/742 68/18722 0.0522812067719646 0.200987674282883 C4orf3/GSTO1/CALM1/VDAC1/CALM2/YWHAE 6 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 4/742 36/18722 0.0529018752468044 0.202271875943664 CTSL/CTSD/CTSV/LGMN 4 GO:0008207 C21-steroid hormone metabolic process 4/742 36/18722 0.0529018752468044 0.202271875943664 EGR1/ADM/DHRS2/CYP11A1 4 GO:0030224 monocyte differentiation 4/742 36/18722 0.0529018752468044 0.202271875943664 JUN/ZFP36L1/CDK6/FOXP1 4 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 4/742 36/18722 0.0529018752468044 0.202271875943664 LRP1/DYNLL1/KIF5B/PHPT1 4 GO:0046466 membrane lipid catabolic process 4/742 36/18722 0.0529018752468044 0.202271875943664 HEXA/FUCA1/ASAH1/HEXB 4 GO:1903539 protein localization to postsynaptic membrane 4/742 36/18722 0.0529018752468044 0.202271875943664 DAG1/DLG1/VAMP2/RAB11A 4 GO:1903749 positive regulation of establishment of protein localization to mitochondrion 4/742 36/18722 0.0529018752468044 0.202271875943664 NMT1/HUWE1/LEPROT/UBE2L3 4 GO:0042098 T cell proliferation 13/742 199/18722 0.0537864212392719 0.205488481543314 CD46/RPS6/TFRC/IL6ST/DLG5/CD81/ANXA1/NCSTN/DLG1/CD55/DOCK8/HES1/IGF2 13 GO:0043271 negative regulation of ion transport 11/742 160/18722 0.0538263350439369 0.205488481543314 CAV1/SLC43A2/ANK3/C4orf3/GABRE/GSTO1/ARL6IP5/CALM1/VDAC1/CALM2/YWHAE 11 GO:0032413 negative regulation of ion transmembrane transporter activity 7/742 86/18722 0.0542711774774662 0.205591861712596 CAV1/ANK3/C4orf3/GSTO1/CALM1/CALM2/YWHAE 7 GO:0035023 regulation of Rho protein signal transduction 7/742 86/18722 0.0542711774774662 0.205591861712596 ADGRG1/ITGB1/MET/KANK1/NRP1/AKAP13/EPS8L1 7 GO:0042692 muscle cell differentiation 22/742 384/18722 0.0542801028484549 0.205591861712596 KRT19/ITGB1/PLEC/KRT8/ISL1/CALR/CD81/SLC9A1/ACTG1/PLD3/AKAP13/YBX1/ACTN4/ADM/OBSL1/GPX1/HES1/YY1/IGF2/MORF4L2/PDCD4/CACYBP 22 GO:0035196 production of miRNAs involved in gene silencing by miRNA 5/742 52/18722 0.0543031516780805 0.205591861712596 EGFR/PUM1/NCOR1/DDX5/ADAR 5 GO:0043090 amino acid import 5/742 52/18722 0.0543031516780805 0.205591861712596 ITGB1/SLC3A2/SLC43A2/SLC1A5/ARL6IP5 5 GO:0045103 intermediate filament-based process 5/742 52/18722 0.0543031516780805 0.205591861712596 MACF1/PLEC/DSP/DST/KRT18 5 GO:0006907 pinocytosis 3/742 22/18722 0.0545340101399248 0.205591861712596 CAV1/CLN3/CDC42 3 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 3/742 22/18722 0.0545340101399248 0.205591861712596 GSTO1/CALM1/CALM2 3 GO:0035024 negative regulation of Rho protein signal transduction 3/742 22/18722 0.0545340101399248 0.205591861712596 ITGB1/MET/KANK1 3 GO:0035089 establishment of apical/basal cell polarity 3/742 22/18722 0.0545340101399248 0.205591861712596 FAT1/CDC42/RHOA 3 GO:0045048 protein insertion into ER membrane 3/742 22/18722 0.0545340101399248 0.205591861712596 CCDC47/EMC1/EMC10 3 GO:0048026 positive regulation of mRNA splicing, via spliceosome 3/742 22/18722 0.0545340101399248 0.205591861712596 TRA2B/CIRBP/PRDX6 3 GO:0060343 trabecula formation 3/742 22/18722 0.0545340101399248 0.205591861712596 FBN2/TGFBR3/ADAMTS1 3 GO:0060965 negative regulation of gene silencing by miRNA 3/742 22/18722 0.0545340101399248 0.205591861712596 NEAT1/KCNQ1OT1/NCOR1 3 GO:0071359 cellular response to dsRNA 3/742 22/18722 0.0545340101399248 0.205591861712596 CAV1/COLEC12/NPM1 3 GO:2000773 negative regulation of cellular senescence 3/742 22/18722 0.0545340101399248 0.205591861712596 PRKDC/CDK6/YBX1 3 GO:0006874 cellular calcium ion homeostasis 25/742 448/18722 0.0545609171468042 0.205591861712596 ATP2B1/HSP90B1/TPT1/LRP1/ITGAV/APP/CAV1/GJA1/GSTO1/ATP2B4/CCDC47/CALR/DIAPH1/CD55/TMEM165/GTF2I/ADM/DDIT3/CALM1/CLN3/HEXB/BCAP31/TGM2/CALM2/YWHAE 25 GO:0010611 regulation of cardiac muscle hypertrophy 6/742 69/18722 0.0554316097167356 0.20855457121148 IL6ST/ATP2B4/SLC9A1/ROCK1/PARP1/YY1 6 GO:0031060 regulation of histone methylation 6/742 69/18722 0.0554316097167356 0.20855457121148 ATRX/BRD4/NSD1/RIF1/RTF1/GATA3 6 GO:0032886 regulation of microtubule-based process 15/742 240/18722 0.0555106996947595 0.208693193677406 AKAP9/MET/DYNC1H1/MACF1/CLIP1/NPM1/TPR/HSPA1A/DIAPH1/HSPA1B/ROCK1/LAMP1/KLHL42/CLTC/RHOA 15 GO:0036294 cellular response to decreased oxygen levels 11/742 161/18722 0.0558106008659182 0.209127537015746 MALAT1/P4HB/EGR1/ZFP36L1/BMP7/SLC9A1/ENO1/PMAIP1/HP1BP3/CITED2/EPAS1 11 GO:0006690 icosanoid metabolic process 9/742 123/18722 0.0558207162674383 0.209127537015746 MGST3/MIF/ANXA1/ATP6V1B1/GPX1/PTGES3/CYP2J2/GPX4/HPGD 9 GO:0071482 cellular response to light stimulus 9/742 123/18722 0.0558207162674383 0.209127537015746 RPL26/NPM1/MME/DDB1/NMT1/DHX36/EIF2AK4/PARP1/YY1 9 GO:0007009 plasma membrane organization 10/742 142/18722 0.0561688184785627 0.209127537015746 PLEC/CAV1/SPESP1/ANK3/FOLR1/SPTBN1/DEGS1/S100A9/SYT7/CLN3 10 GO:0000041 transition metal ion transport 8/742 105/18722 0.0569862370494293 0.209127537015746 SLC39A10/FTH1/TFRC/SLC40A1/SLC39A7/SLC39A1/TMEM165/CLTC 8 GO:2001022 positive regulation of response to DNA damage stimulus 8/742 105/18722 0.0569862370494293 0.209127537015746 EGFR/FUS/RPL26/PRKDC/PMAIP1/RIF1/DDX5/PARP1 8 GO:0019915 lipid storage 7/742 87/18722 0.0571009056560125 0.209127537015746 ITGAV/CAV1/PLIN2/CDS1/NFKBIA/MEST/HEXB 7 GO:0061014 positive regulation of mRNA catabolic process 7/742 87/18722 0.0571009056560125 0.209127537015746 ZFP36L1/TNRC6A/TNRC6B/ROCK1/PUM1/DHX36/CELF1 7 GO:0002934 desmosome organization 2/742 10/18722 0.0571579727469563 0.209127537015746 DSP/DSG2 2 GO:0003056 regulation of vascular associated smooth muscle contraction 2/742 10/18722 0.0571579727469563 0.209127537015746 ATP2B1/RHOA 2 GO:0010968 regulation of microtubule nucleation 2/742 10/18722 0.0571579727469563 0.209127537015746 HSPA1A/HSPA1B 2 GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation 2/742 10/18722 0.0571579727469563 0.209127537015746 NPM1/EIF2AK4 2 GO:0016139 glycoside catabolic process 2/742 10/18722 0.0571579727469563 0.209127537015746 FUCA1/GUSB 2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 2/742 10/18722 0.0571579727469563 0.209127537015746 P4HB/PRDX4 2 GO:0021562 vestibulocochlear nerve development 2/742 10/18722 0.0571579727469563 0.209127537015746 NRP2/NRP1 2 GO:0021903 rostrocaudal neural tube patterning 2/742 10/18722 0.0571579727469563 0.209127537015746 ATP6AP2/HES1 2 GO:0021932 hindbrain radial glia guided cell migration 2/742 10/18722 0.0571579727469563 0.209127537015746 ITGB1/RERE 2 GO:0031340 positive regulation of vesicle fusion 2/742 10/18722 0.0571579727469563 0.209127537015746 ANXA1/KIF5B 2 GO:0033572 transferrin transport 2/742 10/18722 0.0571579727469563 0.209127537015746 TFRC/CLTC 2 GO:0040015 negative regulation of multicellular organism growth 2/742 10/18722 0.0571579727469563 0.209127537015746 LGMN/ADRB1 2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence 2/742 10/18722 0.0571579727469563 0.209127537015746 EMC1/EMC10 2 GO:0048755 branching morphogenesis of a nerve 2/742 10/18722 0.0571579727469563 0.209127537015746 RTN4/RERE 2 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 2/742 10/18722 0.0571579727469563 0.209127537015746 CALM1/CALM2 2 GO:0051409 response to nitrosative stress 2/742 10/18722 0.0571579727469563 0.209127537015746 DUSP6/DDIT3 2 GO:0061299 retina vasculature morphogenesis in camera-type eye 2/742 10/18722 0.0571579727469563 0.209127537015746 LRP5/NRP1 2 GO:0072124 regulation of glomerular mesangial cell proliferation 2/742 10/18722 0.0571579727469563 0.209127537015746 EGR1/BMP7 2 GO:0072203 cell proliferation involved in metanephros development 2/742 10/18722 0.0571579727469563 0.209127537015746 EGR1/BMP7 2 GO:0097084 vascular associated smooth muscle cell development 2/742 10/18722 0.0571579727469563 0.209127537015746 ADM/HES1 2 GO:0140059 dendrite arborization 2/742 10/18722 0.0571579727469563 0.209127537015746 NRP1/TPBG 2 GO:1901524 regulation of mitophagy 2/742 10/18722 0.0571579727469563 0.209127537015746 VPS13C/VDAC1 2 GO:1904668 positive regulation of ubiquitin protein ligase activity 2/742 10/18722 0.0571579727469563 0.209127537015746 SKP1/UBE2C 2 GO:1905383 protein localization to presynapse 2/742 10/18722 0.0571579727469563 0.209127537015746 KIF5B/HSPB1 2 GO:2000169 regulation of peptidyl-cysteine S-nitrosylation 2/742 10/18722 0.0571579727469563 0.209127537015746 ATP2B4/TXN 2 GO:2000674 regulation of type B pancreatic cell apoptotic process 2/742 10/18722 0.0571579727469563 0.209127537015746 TCF7L2/SRSF6 2 GO:0001990 regulation of systemic arterial blood pressure by hormone 4/742 37/18722 0.0575312394340889 0.209127537015746 ENPEP/MME/ATP6AP2/RHOA 4 GO:0006623 protein targeting to vacuole 4/742 37/18722 0.0575312394340889 0.209127537015746 GCC2/VPS13C/LAMP2/GNPTAB 4 GO:0021532 neural tube patterning 4/742 37/18722 0.0575312394340889 0.209127537015746 GLI3/ATP6AP2/TMEM107/HES1 4 GO:0032570 response to progesterone 4/742 37/18722 0.0575312394340889 0.209127537015746 FOS/CLDN4/FOSB/CAV1 4 GO:0043403 skeletal muscle tissue regeneration 4/742 37/18722 0.0575312394340889 0.209127537015746 DAG1/CD81/ANXA1/GPX1 4 GO:0045616 regulation of keratinocyte differentiation 4/742 37/18722 0.0575312394340889 0.209127537015746 ZFP36L1/ROCK1/NCOA3/SRSF6 4 GO:0048846 axon extension involved in axon guidance 4/742 37/18722 0.0575312394340889 0.209127537015746 NRP2/SEMA6A/SEMA6D/NRP1 4 GO:0060306 regulation of membrane repolarization 4/742 37/18722 0.0575312394340889 0.209127537015746 AKAP9/CAV1/GJA5/YWHAE 4 GO:0062237 protein localization to postsynapse 4/742 37/18722 0.0575312394340889 0.209127537015746 DAG1/DLG1/VAMP2/RAB11A 4 GO:1902284 neuron projection extension involved in neuron projection guidance 4/742 37/18722 0.0575312394340889 0.209127537015746 NRP2/SEMA6A/SEMA6D/NRP1 4 GO:1905332 positive regulation of morphogenesis of an epithelium 4/742 37/18722 0.0575312394340889 0.209127537015746 LGR4/GJA1/MAGED1/GATA3 4 GO:0051100 negative regulation of binding 11/742 162/18722 0.0578429520418166 0.210106016975422 JUN/LRPAP1/CAV1/C4orf3/PTPRF/TMSB4X/ROCK1/DDIT3/RSF1/NFKBIA/ID1 11 GO:0007162 negative regulation of cell adhesion 18/742 303/18722 0.0579231921237041 0.210242886914841 FBLN1/LRP1/CDH1/SEMA6A/SPINT2/KANK1/DUSP1/DLG5/TACSTD2/JAM3/MIA3/ANXA1/GLI3/DLG1/ACTN4/RASA1/ERBB3/RHOA 18 GO:1903202 negative regulation of oxidative stress-induced cell death 5/742 53/18722 0.0580931982108198 0.210705138885059 MET/PPIA/TXN/HSPB1/GPX1 5 GO:0034763 negative regulation of transmembrane transport 10/742 143/18722 0.0583579884846618 0.211510244397821 CAV1/SLC43A2/ANK3/C4orf3/GSTO1/ARL6IP5/CALM1/VDAC1/CALM2/YWHAE 10 GO:0002790 peptide secretion 15/742 242/18722 0.0587980992109556 0.212949127640851 EGFR/LRP1/SOX4/GJA1/DPP4/DYNLL1/LRP5/ISL1/ANXA1/KIF5B/TCF7L2/SYT7/SLC16A1/HMGN3/PHPT1 15 GO:0006325 chromatin organization 23/742 409/18722 0.059032610686283 0.213600008194817 BPTF/ATRX/MPHOSPH8/NPM1/TPR/BRD4/KDM5A/RERE/ARID1A/BRD2/ARID4B/NCOR1/CHD2/HP1BP3/BAZ1B/RSF1/KDM5B/SMARCA2/GATA3/HNRNPC/HMGN3/GPX4/HMGA1 23 GO:0000302 response to reactive oxygen species 14/742 222/18722 0.0591507715001032 0.213600008194817 JUN/EGFR/FOS/LDHA/RHOB/MET/DUSP1/SOD3/BMP7/ANXA1/TRA2B/TXN/GPX1/HBA2 14 GO:0007599 hemostasis 14/742 222/18722 0.0591507715001032 0.213600008194817 F5/FBLN1/LMAN1/CAV1/IL6ST/ANXA5/ACTG1/GNAQ/PPIA/GNA12/HSPB1/TFPI2/TLN1/MYL12A 14 GO:0050817 coagulation 14/742 222/18722 0.0591507715001032 0.213600008194817 F5/FBLN1/LMAN1/CAV1/IL6ST/ANXA5/ACTG1/GNAQ/PPIA/GNA12/HSPB1/TFPI2/TLN1/MYL12A 14 GO:0002062 chondrocyte differentiation 8/742 106/18722 0.0596065079842123 0.215088494844418 EFEMP1/GLG1/TRIP11/SERPINH1/POR/GLI3/LTBP3/CREB3L2 8 GO:0009144 purine nucleoside triphosphate metabolic process 7/742 88/18722 0.0600203660451316 0.216265943299015 ALDOA/TMSB4X/ENO1/NME3/PARP1/RAN/RHOA 7 GO:0050779 RNA destabilization 7/742 88/18722 0.0600203660451316 0.216265943299015 ZFP36L1/TNRC6A/TNRC6B/ROCK1/PUM1/DHX36/CELF1 7 GO:0007612 learning 10/742 144/18722 0.0606021474513077 0.217489042231815 JUN/FOS/APP/ITGB1/LGMN/NF1/TPBG/EIF2AK4/VDAC1/CLN3 10 GO:0033135 regulation of peptidyl-serine phosphorylation 10/742 144/18722 0.0606021474513077 0.217489042231815 EGFR/AKAP9/APP/TFRC/CAV1/MIF/ATP2B4/EIF4G1/NSD1/TXN 10 GO:0018210 peptidyl-threonine modification 9/742 125/18722 0.060605294784699 0.217489042231815 APP/GALNT11/PRKDC/BMP7/EIF4G1/ROCK1/CALM1/CALM2/CSNK2B 9 GO:0055007 cardiac muscle cell differentiation 9/742 125/18722 0.060605294784699 0.217489042231815 ITGB1/PLEC/ISL1/CALR/SLC9A1/AKAP13/OBSL1/YY1/CACYBP 9 GO:2000027 regulation of animal organ morphogenesis 9/742 125/18722 0.060605294784699 0.217489042231815 LGR4/BMP7/TACSTD2/ZNRF3/MAGED1/CITED2/GATA3/CDC42/RHOA 9 GO:0003283 atrial septum development 3/742 23/18722 0.0609319217822173 0.217489042231815 SOX4/ISL1/GJA5 3 GO:0006622 protein targeting to lysosome 3/742 23/18722 0.0609319217822173 0.217489042231815 GCC2/LAMP2/GNPTAB 3 GO:0035994 response to muscle stretch 3/742 23/18722 0.0609319217822173 0.217489042231815 FOS/SLC9A1/NFKBIA 3 GO:0042026 protein refolding 3/742 23/18722 0.0609319217822173 0.217489042231815 HSPA5/HSPA1A/HSPA1B 3 GO:0071636 positive regulation of transforming growth factor beta production 3/742 23/18722 0.0609319217822173 0.217489042231815 CD46/FERMT1/ATP6AP2 3 GO:2000737 negative regulation of stem cell differentiation 3/742 23/18722 0.0609319217822173 0.217489042231815 N4BP2L2/HES1/LBH 3 GO:2001169 regulation of ATP biosynthetic process 3/742 23/18722 0.0609319217822173 0.217489042231815 TMSB4X/ENO1/PARP1 3 GO:0050920 regulation of chemotaxis 14/742 223/18722 0.0609321527224357 0.217489042231815 SEMA6A/MET/MYCBP2/DUSP1/MIF/SEMA6D/DPP4/NRP1/JAM3/CALR/TMSB4X/LGMN/TPBG/HSPB1 14 GO:0030834 regulation of actin filament depolymerization 5/742 54/18722 0.0620308019263858 0.220115305366973 SPTAN1/SPTBN1/TRIOBP/DSTN/CAPZB 5 GO:0031050 dsRNA processing 5/742 54/18722 0.0620308019263858 0.220115305366973 EGFR/PUM1/NCOR1/DDX5/ADAR 5 GO:0032330 regulation of chondrocyte differentiation 5/742 54/18722 0.0620308019263858 0.220115305366973 EFEMP1/GLG1/POR/GLI3/LTBP3 5 GO:0070918 production of small RNA involved in gene silencing by RNA 5/742 54/18722 0.0620308019263858 0.220115305366973 EGFR/PUM1/NCOR1/DDX5/ADAR 5 GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II 5/742 54/18722 0.0620308019263858 0.220115305366973 JUN/FOS/EGR1/GATA3/YY1 5 GO:0051656 establishment of organelle localization 22/742 390/18722 0.0620507930946283 0.220115305366973 ARMCX3/ITGB1/SYNE2/DYNC1H1/GJA1/TMED9/TRIP11/ATP6AP1/NPM1/ARHGAP21/KIF5B/DLG1/ACTN4/CFL1/LAMP1/PCM1/KPNB1/CLN3/RAN/CDC42/RAB11A/DYNLT1 22 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 11/742 164/18722 0.0620531288917165 0.220115305366973 UFL1/CAV1/RPL23/HSPA1A/HSPA1B/HECTD1/EIF3H/GNA12/BCAP31/DDA1/SDCBP 11 GO:0003208 cardiac ventricle morphogenesis 6/742 71/18722 0.0620689514931566 0.220115305366973 LRP2/TGFBR3/SOX4/DSP/ISL1/GATA3 6 GO:0033555 multicellular organismal response to stress 6/742 71/18722 0.0620689514931566 0.220115305366973 VWA1/GJA1/DPP4/EIF4G1/ADRB1/VDAC1 6 GO:0002478 antigen processing and presentation of exogenous peptide antigen 4/742 38/18722 0.0623700978539605 0.220549952325387 CTSL/CTSD/CTSV/LGMN 4 GO:0010613 positive regulation of cardiac muscle hypertrophy 4/742 38/18722 0.0623700978539605 0.220549952325387 IL6ST/SLC9A1/ROCK1/PARP1 4 GO:0099622 cardiac muscle cell membrane repolarization 4/742 38/18722 0.0623700978539605 0.220549952325387 AKAP9/GJA5/ATP1A1/YWHAE 4 GO:2000279 negative regulation of DNA biosynthetic process 4/742 38/18722 0.0623700978539605 0.220549952325387 DUSP1/GJA1/HNRNPA1/HNRNPC 4 GO:0051961 negative regulation of nervous system development 10/742 145/18722 0.0629015990417201 0.222111436215938 SEMA6A/SEMA6D/RTN4/NRP1/BMP7/NF1/PCM1/ID1/HES1/DYNLT1 10 GO:0061351 neural precursor cell proliferation 10/742 145/18722 0.0629015990417201 0.222111436215938 LRP2/SPINT1/ADGRG1/SPINT2/SLC6A4/GLI3/NF1/RERE/PCM1/RHOA 10 GO:0009199 ribonucleoside triphosphate metabolic process 7/742 89/18722 0.063029864216862 0.222246630429192 ALDOA/TMSB4X/ENO1/NME3/PARP1/RAN/RHOA 7 GO:0014910 regulation of smooth muscle cell migration 7/742 89/18722 0.063029864216862 0.222246630429192 LRP1/IQGAP1/SEMA6D/ADAMTS1/NRP1/GNA12/RHOA 7 GO:0008037 cell recognition 14/742 225/18722 0.0646026177426939 0.22762976579808 APP/ALDOA/BSG/CADM1/SPESP1/COLEC12/RTN4/NRP1/FOLR1/CD81/DLG1/DOCK8/VDAC2/CCT3 14 GO:0014743 regulation of muscle hypertrophy 6/742 72/18722 0.0655561868467494 0.229216283593748 IL6ST/ATP2B4/SLC9A1/ROCK1/PARP1/YY1 6 GO:0033045 regulation of sister chromatid segregation 6/742 72/18722 0.0655561868467494 0.229216283593748 DUSP1/TPR/NEK6/ANAPC11/UBE2C/LCMT1 6 GO:0042246 tissue regeneration 6/742 72/18722 0.0655561868467494 0.229216283593748 DAG1/CD81/ANXA1/PTPN12/CPQ/GPX1 6 GO:1905818 regulation of chromosome separation 6/742 72/18722 0.0655561868467494 0.229216283593748 DUSP1/TPR/NEK6/ANAPC11/UBE2C/LCMT1 6 GO:0031668 cellular response to extracellular stimulus 15/742 246/18722 0.0657658083091837 0.229216283593748 JUN/ATP2B1/FOS/HSPA5/SLC2A1/PLEC/SLC38A2/CTSV/TNRC6A/FOLR1/EIF4G1/PMAIP1/HNRNPA1/LAMP2/EIF2AK4 15 GO:0003229 ventricular cardiac muscle tissue development 5/742 55/18722 0.0661155236963516 0.229216283593748 LRP2/TGFBR3/DSP/DSG2/ISL1 5 GO:0006414 translational elongation 5/742 55/18722 0.0661155236963516 0.229216283593748 EEF1A1/EEF1B2/NEMF/TUFM/EIF5A 5 GO:0031113 regulation of microtubule polymerization 5/742 55/18722 0.0661155236963516 0.229216283593748 AKAP9/MET/CLIP1/HSPA1A/HSPA1B 5 GO:0044091 membrane biogenesis 5/742 55/18722 0.0661155236963516 0.229216283593748 CAV1/ANK3/SPTBN1/SERINC1/S100A10 5 GO:0042475 odontogenesis of dentin-containing tooth 7/742 90/18722 0.0661296217054928 0.229216283593748 CSF3R/LAMA5/BSG/ANKRD11/BMP7/GLI3/ADM 7 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 7/742 90/18722 0.0661296217054928 0.229216283593748 JUN/GJA1/ADAMTS1/GNA12/RHOA/HPGD/PDCD4 7 GO:0007389 pattern specification process 24/742 436/18722 0.0663301371270863 0.229216283593748 LRP2/NRP2/ADGRG1/GALNT11/WLS/BPTF/PBX1/PRKDC/LRP5/NRP1/BMP7/ISL1/NR2F2/FOLR1/GLI3/ATP6AP2/TRA2B/PGAP1/IRX2/DDIT3/TMEM107/CITED2/HES1/YY1 24 GO:0008217 regulation of blood pressure 12/742 186/18722 0.0669534227290163 0.229216283593748 ATP2B1/ENPEP/GJA1/LRP5/NR2F2/GJA5/MME/ATP6AP2/ADRB1/ATP1A1/ADM/RHOA 12 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 12/742 186/18722 0.0669534227290163 0.229216283593748 GAPDH/TFRC/WLS/GJA1/BRD4/TMED4/AKAP13/SLC44A2/DHX36/TGM2/NEK6/RHOA 12 GO:0014742 positive regulation of muscle hypertrophy 4/742 39/18722 0.0674162027285891 0.229216283593748 IL6ST/SLC9A1/ROCK1/PARP1 4 GO:1901021 positive regulation of calcium ion transmembrane transporter activity 4/742 39/18722 0.0674162027285891 0.229216283593748 GSTO1/SLC9A1/CALM1/CALM2 4 GO:2000249 regulation of actin cytoskeleton reorganization 4/742 39/18722 0.0674162027285891 0.229216283593748 IQGAP2/NRP1/CDC42/PHPT1 4 GO:0002726 positive regulation of T cell cytokine production 3/742 24/18722 0.0676622265380053 0.229216283593748 CD81/CD55/GATA3 3 GO:0007035 vacuolar acidification 3/742 24/18722 0.0676622265380053 0.229216283593748 GRN/ATP6AP2/CLN3 3 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress 3/742 24/18722 0.0676622265380053 0.229216283593748 HSPA5/ATF6/DDIT3 3 GO:0050855 regulation of B cell receptor signaling pathway 3/742 24/18722 0.0676622265380053 0.229216283593748 SLC39A10/CD81/FOXP1 3 GO:0061162 establishment of monopolar cell polarity 3/742 24/18722 0.0676622265380053 0.229216283593748 FAT1/CDC42/RHOA 3 GO:0070841 inclusion body assembly 3/742 24/18722 0.0676622265380053 0.229216283593748 HSPA1A/HSPA1B/DNAJB1 3 GO:0071577 zinc ion transmembrane transport 3/742 24/18722 0.0676622265380053 0.229216283593748 SLC39A10/SLC39A7/SLC39A1 3 GO:0120255 olefinic compound biosynthetic process 3/742 24/18722 0.0676622265380053 0.229216283593748 EGR1/ADM/HSD17B1 3 GO:1903077 negative regulation of protein localization to plasma membrane 3/742 24/18722 0.0676622265380053 0.229216283593748 TMEM59/HECTD1/CLTC 3 GO:0001765 membrane raft assembly 2/742 11/18722 0.0680688842170099 0.229216283593748 CAV1/S100A10 2 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 2/742 11/18722 0.0680688842170099 0.229216283593748 CD46/CD55 2 GO:0003093 regulation of glomerular filtration 2/742 11/18722 0.0680688842170099 0.229216283593748 GJA1/GJA5 2 GO:0003139 secondary heart field specification 2/742 11/18722 0.0680688842170099 0.229216283593748 LRP2/ISL1 2 GO:0003174 mitral valve development 2/742 11/18722 0.0680688842170099 0.229216283593748 SOX4/GJA5 2 GO:0003263 cardioblast proliferation 2/742 11/18722 0.0680688842170099 0.229216283593748 ISL1/HES1 2 GO:0003264 regulation of cardioblast proliferation 2/742 11/18722 0.0680688842170099 0.229216283593748 ISL1/HES1 2 GO:0006020 inositol metabolic process 2/742 11/18722 0.0680688842170099 0.229216283593748 SLC5A3/ISYNA1 2 GO:0009313 oligosaccharide catabolic process 2/742 11/18722 0.0680688842170099 0.229216283593748 MANBA/HEXB 2 GO:0021561 facial nerve development 2/742 11/18722 0.0680688842170099 0.229216283593748 NRP2/NRP1 2 GO:0021604 cranial nerve structural organization 2/742 11/18722 0.0680688842170099 0.229216283593748 NRP2/NRP1 2 GO:0021610 facial nerve morphogenesis 2/742 11/18722 0.0680688842170099 0.229216283593748 NRP2/NRP1 2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase 2/742 11/18722 0.0680688842170099 0.229216283593748 ACADVL/ETFA 2 GO:0033690 positive regulation of osteoblast proliferation 2/742 11/18722 0.0680688842170099 0.229216283593748 ITGAV/LRP5 2 GO:0035457 cellular response to interferon-alpha 2/742 11/18722 0.0680688842170099 0.229216283593748 TPR/GATA3 2 GO:0043589 skin morphogenesis 2/742 11/18722 0.0680688842170099 0.229216283593748 ITGB4/ITGA6 2 GO:0045657 positive regulation of monocyte differentiation 2/742 11/18722 0.0680688842170099 0.229216283593748 JUN/ZFP36L1 2 GO:0048096 chromatin-mediated maintenance of transcription 2/742 11/18722 0.0680688842170099 0.229216283593748 SERTAD1/ARID1A 2 GO:0048102 autophagic cell death 2/742 11/18722 0.0680688842170099 0.229216283593748 CTSV/LAMP1 2 GO:0048680 positive regulation of axon regeneration 2/742 11/18722 0.0680688842170099 0.229216283593748 LRP1/GRN 2 GO:0048715 negative regulation of oligodendrocyte differentiation 2/742 11/18722 0.0680688842170099 0.229216283593748 NF1/HES1 2 GO:0051561 positive regulation of mitochondrial calcium ion concentration 2/742 11/18722 0.0680688842170099 0.229216283593748 BCAP31/TGM2 2 GO:0051657 maintenance of organelle location 2/742 11/18722 0.0680688842170099 0.229216283593748 AKAP9/ARHGAP21 2 GO:0071679 commissural neuron axon guidance 2/742 11/18722 0.0680688842170099 0.229216283593748 DAG1/NRP1 2 GO:0072110 glomerular mesangial cell proliferation 2/742 11/18722 0.0680688842170099 0.229216283593748 EGR1/BMP7 2 GO:0072173 metanephric tubule morphogenesis 2/742 11/18722 0.0680688842170099 0.229216283593748 LGR4/HES1 2 GO:0072497 mesenchymal stem cell differentiation 2/742 11/18722 0.0680688842170099 0.229216283593748 LTBP3/KRT18 2 GO:0090030 regulation of steroid hormone biosynthetic process 2/742 11/18722 0.0680688842170099 0.229216283593748 POR/ATP1A1 2 GO:0090160 Golgi to lysosome transport 2/742 11/18722 0.0680688842170099 0.229216283593748 LAMP1/CLN3 2 GO:0097050 type B pancreatic cell apoptotic process 2/742 11/18722 0.0680688842170099 0.229216283593748 TCF7L2/SRSF6 2 GO:0098935 dendritic transport 2/742 11/18722 0.0680688842170099 0.229216283593748 KIF5B/PURA 2 GO:0106049 regulation of cellular response to osmotic stress 2/742 11/18722 0.0680688842170099 0.229216283593748 CLN3/EFHD1 2 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation 2/742 11/18722 0.0680688842170099 0.229216283593748 N4BP2L2/HES1 2 GO:1902667 regulation of axon guidance 2/742 11/18722 0.0680688842170099 0.229216283593748 MYCBP2/NRP1 2 GO:1902915 negative regulation of protein polyubiquitination 2/742 11/18722 0.0680688842170099 0.229216283593748 TRIM44/PPIA 2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway 2/742 11/18722 0.0680688842170099 0.229216283593748 HSPA1A/HSPA1B 2 GO:1903897 regulation of PERK-mediated unfolded protein response 2/742 11/18722 0.0680688842170099 0.229216283593748 HSPA5/PPP1R15A 2 GO:1903961 positive regulation of anion transmembrane transport 2/742 11/18722 0.0680688842170099 0.229216283593748 TCAF1/ITGB1 2 GO:1904181 positive regulation of membrane depolarization 2/742 11/18722 0.0680688842170099 0.229216283593748 ANK3/PARP1 2 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 9/742 128/18722 0.0682602772999947 0.229704202903252 APP/GADD45B/ARL6IP5/EMC10/RB1CC1/RNF13/GADD45G/CDC42/SDCBP 9 GO:0060326 cell chemotaxis 18/742 310/18722 0.0688585746840897 0.23155980867216 CSF3R/MET/PLEC/BSG/DUSP1/MIF/DPP4/FLT1/NRP1/JAM3/CALR/TMSB4X/ANXA1/LGMN/S100A9/TPBG/PPIA/HSPB1 18 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 6/742 73/18722 0.0691557739436618 0.23200521273234 LRP1/DYNLL1/LRP5/KIF5B/HMGN3/PHPT1 6 GO:0070988 demethylation 6/742 73/18722 0.0691557739436618 0.23200521273234 POR/KDM5A/USP9X/TET2/KDM5B/GATA3 6 GO:0006885 regulation of pH 7/742 91/18722 0.06931977611193 0.23200521273234 GRN/ATP6AP1/SLC9A1/ATP6AP2/TMEM165/ATP6V1B1/CLN3 7 GO:0051983 regulation of chromosome segregation 7/742 91/18722 0.06931977611193 0.23200521273234 DUSP1/TPR/PUM1/NEK6/ANAPC11/UBE2C/LCMT1 7 GO:0055006 cardiac cell development 7/742 91/18722 0.06931977611193 0.23200521273234 PLEC/TGFBR3/ISL1/AKAP13/OBSL1/YY1/PDCD4 7 GO:0060191 regulation of lipase activity 7/742 91/18722 0.06931977611193 0.23200521273234 EGFR/LRP1/FLT1/POR/ANXA1/GNAQ/RHOA 7 GO:1990874 vascular associated smooth muscle cell proliferation 7/742 91/18722 0.06931977611193 0.23200521273234 JUN/GJA1/ADAMTS1/GNA12/RHOA/HPGD/PDCD4 7 GO:0033002 muscle cell proliferation 15/742 248/18722 0.0694491090500655 0.232280703254789 JUN/EGFR/SF1/TGFBR3/GJA1/ADAMTS1/PRKDC/TCF7L2/FOXP1/GNA12/CITED2/TGM2/RHOA/HPGD/PDCD4 15 GO:0070507 regulation of microtubule cytoskeleton organization 10/742 148/18722 0.0701343046795465 0.234255216441487 AKAP9/MET/DYNC1H1/CLIP1/TPR/HSPA1A/HSPA1B/ROCK1/CLTC/RHOA 10 GO:1903900 regulation of viral life cycle 10/742 148/18722 0.0701343046795465 0.234255216441487 P4HB/HACD3/PKN2/MPHOSPH8/DDB1/PPIA/LARP1/DDX5/ADAR/BANF1 10 GO:0022029 telencephalon cell migration 5/742 56/18722 0.0703466964311366 0.234488988103789 ADGRG1/LAMB1/RTN4/GLI3/RHOA 5 GO:0031529 ruffle organization 5/742 56/18722 0.0703466964311366 0.234488988103789 KANK1/CAV1/TACSTD2/PFN1/EPS8L1 5 GO:0048255 mRNA stabilization 5/742 56/18722 0.0703466964311366 0.234488988103789 FUS/YBX1/LARP1/CIRBP/HNRNPC 5 GO:0061387 regulation of extent of cell growth 8/742 110/18722 0.0708367479521266 0.235963273690833 LRP1/GOLGA4/SEMA6A/MACF1/SEMA6D/RTN4/NRP1/RAB11A 8 GO:0000070 mitotic sister chromatid segregation 11/742 168/18722 0.0710626699728056 0.236397030077885 DUSP1/ATRX/TPR/NIPBL/KPNB1/RAN/NEK6/RAB11A/ANAPC11/UBE2C/LCMT1 11 GO:0099173 postsynapse organization 11/742 168/18722 0.0710626699728056 0.236397030077885 NRP2/IGF1R/NRP1/ACTG1/LGMN/DLG1/WASF2/PPP1R9A/CFL1/DHX36/CDC42 11 GO:0009410 response to xenobiotic stimulus 25/742 462/18722 0.0723008048667732 0.240353954267739 JUN/EGFR/FOS/HSPA5/CDH1/LDHA/RPN2/FOSB/TFRC/DUSP6/SLC6A4/GSTO1/POR/CALR/ANXA1/PLIN2/ATP1A1/GNA12/HADHA/GATA3/GPX1/S100A10/ADIRF/CYP2J2/RHOA 25 GO:0031058 positive regulation of histone modification 7/742 92/18722 0.0726003813627874 0.240599451301532 ISL1/BRD4/NIPBL/RIF1/BRD7/RTF1/GATA3 7 GO:0030501 positive regulation of bone mineralization 4/742 40/18722 0.072666878814147 0.240599451301532 FBN2/ATP2B1/BMP7/ATRAID 4 GO:0046365 monosaccharide catabolic process 4/742 40/18722 0.072666878814147 0.240599451301532 LRP5/ENO1/GLB1/FUT8 4 GO:0060412 ventricular septum morphogenesis 4/742 40/18722 0.072666878814147 0.240599451301532 TGFBR3/SOX4/CITED2/HES1 4 GO:0072210 metanephric nephron development 4/742 40/18722 0.072666878814147 0.240599451301532 LGR4/EGR1/IRX2/HES1 4 GO:2000781 positive regulation of double-strand break repair 4/742 40/18722 0.072666878814147 0.240599451301532 FUS/PRKDC/RIF1/PARP1 4 GO:0042476 odontogenesis 9/742 130/18722 0.0736851614335794 0.2435437932792 CSF3R/LAMA5/LAMB1/BSG/ANKRD11/BMP7/GLI3/ADM/RHOA 9 GO:0016570 histone modification 25/742 463/18722 0.0737040427029158 0.2435437932792 UFL1/ATRX/ISL1/BRD4/KMT2C/DDB1/ASH1L/KDM5A/NIPBL/NCOA3/TET2/NSD1/RIF1/BAZ1B/KDM5B/BRD7/RTF1/HUWE1/GATA3/USP22/TBL1X/SKP1/PHF20/IGF2/MORF4L2 25 GO:0023061 signal release 25/742 463/18722 0.0737040427029158 0.2435437932792 EGFR/LRP1/WLS/SOX4/GJA1/SLC6A4/DPP4/DYNLL1/LRP5/ISL1/ANXA1/KIF5B/PPP1R9A/TCF7L2/SYT7/VAMP2/ADM/KDM5B/CALM1/SLC16A1/GATA3/HMGN3/PHPT1/CYP19A1/CGA 25 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 3/742 25/18722 0.0747141937747072 0.24397471969601 GJA1/GJA5/RHOA 3 GO:0010447 response to acidic pH 3/742 25/18722 0.0747141937747072 0.24397471969601 SERPINF1/SLC9A1/LGMN 3 GO:0015012 heparan sulfate proteoglycan biosynthetic process 3/742 25/18722 0.0747141937747072 0.24397471969601 EXTL2/B3GAT3/TCF7L2 3 GO:0016540 protein autoprocessing 3/742 25/18722 0.0747141937747072 0.24397471969601 CTSL/PISD/PARP1 3 GO:0033622 integrin activation 3/742 25/18722 0.0747141937747072 0.24397471969601 JAM3/FERMT1/TLN1 3 GO:0034389 lipid droplet organization 3/742 25/18722 0.0747141937747072 0.24397471969601 FAF2/CDS1/PPIA 3 GO:0046039 GTP metabolic process 3/742 25/18722 0.0747141937747072 0.24397471969601 NME3/RAN/RHOA 3 GO:0061339 establishment or maintenance of monopolar cell polarity 3/742 25/18722 0.0747141937747072 0.24397471969601 FAT1/CDC42/RHOA 3 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 3/742 25/18722 0.0747141937747072 0.24397471969601 HSPA1A/HSPA1B/NFKBIA 3 GO:0072012 glomerulus vasculature development 3/742 25/18722 0.0747141937747072 0.24397471969601 EGR1/BMP7/HES1 3 GO:1903792 negative regulation of anion transport 3/742 25/18722 0.0747141937747072 0.24397471969601 SLC43A2/GABRE/ARL6IP5 3 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA 3/742 25/18722 0.0747141937747072 0.24397471969601 EGFR/NCOR1/DDX5 3 GO:1904754 positive regulation of vascular associated smooth muscle cell migration 3/742 25/18722 0.0747141937747072 0.24397471969601 LRP1/IQGAP1/ADAMTS1 3 GO:1905048 regulation of metallopeptidase activity 3/742 25/18722 0.0747141937747072 0.24397471969601 LRP1/CLDN4/TIMP3 3 GO:0050891 multicellular organismal water homeostasis 5/742 57/18722 0.0747234313562881 0.24397471969601 CLDN4/MET/PLEC/LSR/ATP6V1B1 5 GO:0051205 protein insertion into membrane 5/742 57/18722 0.0747234313562881 0.24397471969601 EGFR/CCDC47/EMC1/EMC10/NMT1 5 GO:0061005 cell differentiation involved in kidney development 5/742 57/18722 0.0747234313562881 0.24397471969601 IQGAP1/LGR4/GLI3/GATA3/HES1 5 GO:0097120 receptor localization to synapse 5/742 57/18722 0.0747234313562881 0.24397471969601 DAG1/KIF5B/DLG1/VAMP2/RAB11A 5 GO:0070665 positive regulation of leukocyte proliferation 10/742 150/18722 0.0752368060036876 0.245488653671213 CD46/SLC39A10/TFRC/MIF/IL6ST/CD81/ANXA1/CD55/HES1/IGF2 10 GO:0045637 regulation of myeloid cell differentiation 13/742 210/18722 0.0753004761412157 0.245534225833403 JUN/FBN1/FOS/CSF3R/PRKDC/ZFP36L1/ATP6AP1/ESRRA/HSPA1A/CDK6/HSPA1B/FOXP1/NFKBIA 13 GO:0018212 peptidyl-tyrosine modification 21/742 378/18722 0.0758925980286832 0.247069622191692 EGFR/EFEMP1/APP/MET/CAV1/IQGAP1/MIF/IL6ST/EPHB4/CSH1/FLT1/TPST2/IGF1R/NRP1/ISL1/PRLR/CD81/ERBB3/BAZ1B/HES1/IGF2 21 GO:0090398 cellular senescence 7/742 93/18722 0.0759714081192672 0.247069622191692 PRKDC/CALR/CDK6/YBX1/YPEL3/NEK6/HMGA1 7 GO:0106027 neuron projection organization 7/742 93/18722 0.0759714081192672 0.247069622191692 APP/IGF1R/LGMN/PPP1R9A/CFL1/DHX36/CDC42 7 GO:1901019 regulation of calcium ion transmembrane transporter activity 7/742 93/18722 0.0759714081192672 0.247069622191692 AHNAK/C4orf3/GSTO1/SLC9A1/CALM1/CALM2/YWHAE 7 GO:0045732 positive regulation of protein catabolic process 14/742 231/18722 0.0764888958950833 0.248443850657632 LRP2/LRP1/CTSC/CAV1/GJA1/TMEM259/HSPA1A/CD81/DDB1/HSPA1B/HECTD1/HUWE1/BCAP31/DDA1 14 GO:0018022 peptidyl-lysine methylation 9/742 131/18722 0.076494554018271 0.248443850657632 ATRX/BRD4/KMT2C/ASH1L/TET2/NSD1/RIF1/RTF1/GATA3 9 GO:1902369 negative regulation of RNA catabolic process 6/742 75/18722 0.0766911422572253 0.248755248030658 FUS/YBX1/DHX36/LARP1/CIRBP/HNRNPC 6 GO:2001259 positive regulation of cation channel activity 6/742 75/18722 0.0766911422572253 0.248755248030658 ANK3/GSTO1/TMSB4X/KIF5B/CALM1/CALM2 6 GO:0042110 T cell activation 26/742 487/18722 0.0767843819986928 0.248894256609936 CD46/CTSL/RPS6/TFRC/CAV1/SOX4/IL6ST/EGR1/PRKDC/ZFP36L1/DPP4/DDOST/DLG5/CD81/ANXA1/GLI3/NCSTN/DLG1/CD55/FOXP1/EIF2AK4/GATA3/DOCK8/HES1/RHOA/IGF2 26 GO:1903037 regulation of leukocyte cell-cell adhesion 19/742 336/18722 0.0771003855106677 0.24975469142472 CD46/TFRC/CAV1/SOX4/IL6ST/DPP4/DLG5/MIA3/NFAT5/CD81/ANXA1/GLI3/DLG1/CD55/GATA3/DOCK8/HES1/RHOA/IGF2 19 GO:0030902 hindbrain development 10/742 151/18722 0.0778727284953418 0.250768704864664 HSPA5/ITGB1/WLS/SLC6A4/NAGLU/BMP7/NCSTN/RERE/SDF4/HES1 10 GO:0071333 cellular response to glucose stimulus 10/742 151/18722 0.0778727284953418 0.250768704864664 LRP1/SERPINF1/SOX4/DYNLL1/LRP5/IGF1R/KIF5B/TRA2B/HMGN3/PHPT1 10 GO:1904064 positive regulation of cation transmembrane transport 10/742 151/18722 0.0778727284953418 0.250768704864664 AKAP9/KCNN4/ANK3/GSTO1/TMSB4X/SLC9A1/KIF5B/ACTN4/CALM1/CALM2 10 GO:0042307 positive regulation of protein import into nucleus 4/742 41/18722 0.0781190487987976 0.250768704864664 CDH1/TPR/GLI3/RAN 4 GO:0048286 lung alveolus development 4/742 41/18722 0.0781190487987976 0.250768704864664 LTBP3/MAN2A1/MAN1A2/PTGES3 4 GO:0051693 actin filament capping 4/742 41/18722 0.0781190487987976 0.250768704864664 SPTAN1/SPTBN1/TRIOBP/CAPZB 4 GO:0071470 cellular response to osmotic stress 4/742 41/18722 0.0781190487987976 0.250768704864664 SLC2A1/ZFP36L1/CLN3/EFHD1 4 GO:0046890 regulation of lipid biosynthetic process 11/742 171/18722 0.078341773953463 0.250768704864664 SF1/ORMDL1/EGR1/POR/ANXA1/ATP1A1/MBTPS1/ACADVL/ADM/ASAH1/CGA 11 GO:0032387 negative regulation of intracellular transport 5/742 58/18722 0.0792446247038133 0.250768704864664 LMAN1/TPR/FERMT1/OS9/TXN 5 GO:0045604 regulation of epidermal cell differentiation 5/742 58/18722 0.0792446247038133 0.250768704864664 ZFP36L1/ROCK1/NCOA3/SRSF6/HES1 5 GO:0001738 morphogenesis of a polarized epithelium 7/742 94/18722 0.0794327443306874 0.250768704864664 LAMA5/DLG5/ZNRF3/ACTG1/FAT1/CDC42/RHOA 7 GO:0051702 biological process involved in interaction with symbiont 7/742 94/18722 0.0794327443306874 0.250768704864664 JUN/GAPDH/DDB1/STOM/CFL1/EIF2AK4/GPX1 7 GO:0002903 negative regulation of B cell apoptotic process 2/742 12/18722 0.0795962204914561 0.250768704864664 SLC39A10/FOXP1 2 GO:0006703 estrogen biosynthetic process 2/742 12/18722 0.0795962204914561 0.250768704864664 HSD17B1/CYP19A1 2 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway 2/742 12/18722 0.0795962204914561 0.250768704864664 LRP1/PTPN12 2 GO:0021559 trigeminal nerve development 2/742 12/18722 0.0795962204914561 0.250768704864664 NRP1/ISL1 2 GO:0021978 telencephalon regionalization 2/742 12/18722 0.0795962204914561 0.250768704864664 ADGRG1/TRA2B 2 GO:0031453 positive regulation of heterochromatin assembly 2/742 12/18722 0.0795962204914561 0.250768704864664 MPHOSPH8/TPR 2 GO:0034086 maintenance of sister chromatid cohesion 2/742 12/18722 0.0795962204914561 0.250768704864664 ATRX/NIPBL 2 GO:0034088 maintenance of mitotic sister chromatid cohesion 2/742 12/18722 0.0795962204914561 0.250768704864664 ATRX/NIPBL 2 GO:0034333 adherens junction assembly 2/742 12/18722 0.0795962204914561 0.250768704864664 DLG5/JAM3 2 GO:0035739 CD4-positive, alpha-beta T cell proliferation 2/742 12/18722 0.0795962204914561 0.250768704864664 CD81/CD55 2 GO:0042118 endothelial cell activation 2/742 12/18722 0.0795962204914561 0.250768704864664 PPIA/FOXP1 2 GO:0043696 dedifferentiation 2/742 12/18722 0.0795962204914561 0.250768704864664 CDK6/NCOA3 2 GO:0043697 cell dedifferentiation 2/742 12/18722 0.0795962204914561 0.250768704864664 CDK6/NCOA3 2 GO:0045605 negative regulation of epidermal cell differentiation 2/742 12/18722 0.0795962204914561 0.250768704864664 SRSF6/HES1 2 GO:0045683 negative regulation of epidermis development 2/742 12/18722 0.0795962204914561 0.250768704864664 SRSF6/HES1 2 GO:0045916 negative regulation of complement activation 2/742 12/18722 0.0795962204914561 0.250768704864664 CD46/CD55 2 GO:0051001 negative regulation of nitric-oxide synthase activity 2/742 12/18722 0.0795962204914561 0.250768704864664 CAV1/ATP2B4 2 GO:0070572 positive regulation of neuron projection regeneration 2/742 12/18722 0.0795962204914561 0.250768704864664 LRP1/GRN 2 GO:0071287 cellular response to manganese ion 2/742 12/18722 0.0795962204914561 0.250768704864664 HSPA5/APP 2 GO:0071472 cellular response to salt stress 2/742 12/18722 0.0795962204914561 0.250768704864664 ZFP36L1/EFHD1 2 GO:0071872 cellular response to epinephrine stimulus 2/742 12/18722 0.0795962204914561 0.250768704864664 ATP2B4/SLC9A1 2 GO:0072520 seminiferous tubule development 2/742 12/18722 0.0795962204914561 0.250768704864664 ADGRG1/ATRX 2 GO:0072584 caveolin-mediated endocytosis 2/742 12/18722 0.0795962204914561 0.250768704864664 CAV1/CLN3 2 GO:0090385 phagosome-lysosome fusion 2/742 12/18722 0.0795962204914561 0.250768704864664 SYT7/CLN3 2 GO:0120263 positive regulation of heterochromatin organization 2/742 12/18722 0.0795962204914561 0.250768704864664 MPHOSPH8/TPR 2 GO:1903332 regulation of protein folding 2/742 12/18722 0.0795962204914561 0.250768704864664 HSPA5/GRN 2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA 2/742 12/18722 0.0795962204914561 0.250768704864664 EGFR/DDX5 2 GO:1904667 negative regulation of ubiquitin protein ligase activity 2/742 12/18722 0.0795962204914561 0.250768704864664 RPS20/RPL23 2 GO:2000035 regulation of stem cell division 2/742 12/18722 0.0795962204914561 0.250768704864664 NCOA3/LBH 2 GO:2000561 regulation of CD4-positive, alpha-beta T cell proliferation 2/742 12/18722 0.0795962204914561 0.250768704864664 CD81/CD55 2 GO:2001204 regulation of osteoclast development 2/742 12/18722 0.0795962204914561 0.250768704864664 FBN1/ATP6AP1 2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 6/742 76/18722 0.080626171337874 0.253851680311726 MIF/RPL26/PMAIP1/TMEM109/DDX5/EIF5A 6 GO:0042770 signal transduction in response to DNA damage 11/742 172/18722 0.0808683357576948 0.254289992770854 ATRX/MIF/SOX4/RPL26/PRKDC/PPP1R10/NPM1/PMAIP1/EIF2AK4/DDX5/USP10 11 GO:1901136 carbohydrate derivative catabolic process 11/742 172/18722 0.0808683357576948 0.254289992770854 CTSL/HEXA/NAGLU/FUCA1/MANBA/GPC1/GUSB/GNS/GLB1/CST3/HEXB 11 GO:0010875 positive regulation of cholesterol efflux 3/742 26/18722 0.082076408803199 0.256294222179395 LRP1/CAV1/NFKBIA 3 GO:0021680 cerebellar Purkinje cell layer development 3/742 26/18722 0.082076408803199 0.256294222179395 HSPA5/NAGLU/RERE 3 GO:0032515 negative regulation of phosphoprotein phosphatase activity 3/742 26/18722 0.082076408803199 0.256294222179395 BOD1L1/PPP1R15A/ROCK1 3 GO:0034063 stress granule assembly 3/742 26/18722 0.082076408803199 0.256294222179395 PRRC2C/DYNC1H1/CIRBP 3 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 3/742 26/18722 0.082076408803199 0.256294222179395 HSPA1A/HSPA1B/NFKBIA 3 GO:0048843 negative regulation of axon extension involved in axon guidance 3/742 26/18722 0.082076408803199 0.256294222179395 SEMA6A/SEMA6D/NRP1 3 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 3/742 26/18722 0.082076408803199 0.256294222179395 GSTO1/CALM1/CALM2 3 GO:0060352 cell adhesion molecule production 3/742 26/18722 0.082076408803199 0.256294222179395 CAV1/COLEC12/PPIA 3 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA 3/742 26/18722 0.082076408803199 0.256294222179395 EGFR/NCOR1/DDX5 3 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway 3/742 26/18722 0.082076408803199 0.256294222179395 ATP2B4/ADRB1/AKAP13 3 GO:1904376 negative regulation of protein localization to cell periphery 3/742 26/18722 0.082076408803199 0.256294222179395 TMEM59/HECTD1/CLTC 3 GO:0008593 regulation of Notch signaling pathway 7/742 95/18722 0.0829841959273238 0.258801722147083 CD46/AAK1/GALNT11/IL6ST/BMP7/NFKBIA/HES1 7 GO:0042982 amyloid precursor protein metabolic process 7/742 95/18722 0.0829841959273238 0.258801722147083 DHCR24/ITM2B/RTN4/NCSTN/DLG1/ROCK1/CLN3 7 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 8/742 114/18722 0.0832734513189324 0.259068928728712 TGFBR3/BMP7/FERMT1/CITED2/PARP1/HES1/CSNK2B/SDCBP 8 GO:1903008 organelle disassembly 8/742 114/18722 0.0832734513189324 0.259068928728712 UFL1/VPS13C/KIF5B/RB1CC1/HUWE1/VDAC1/TEX264/UFC1 8 GO:0071331 cellular response to hexose stimulus 10/742 153/18722 0.0833143819829737 0.259068928728712 LRP1/SERPINF1/SOX4/DYNLL1/LRP5/IGF1R/KIF5B/TRA2B/HMGN3/PHPT1 10 GO:0006338 chromatin remodeling 15/742 255/18722 0.0834082990271036 0.259068928728712 BPTF/ATRX/NPM1/KDM5A/RERE/ARID1A/BRD2/HP1BP3/BAZ1B/RSF1/KDM5B/SMARCA2/GATA3/HNRNPC/HMGA1 15 GO:0000413 protein peptidyl-prolyl isomerization 4/742 42/18722 0.0837692587326426 0.259068928728712 NKTR/PPIG/RANBP2/PPIA 4 GO:0014912 negative regulation of smooth muscle cell migration 4/742 42/18722 0.0837692587326426 0.259068928728712 LRP1/SEMA6D/GNA12/RHOA 4 GO:0030574 collagen catabolic process 4/742 42/18722 0.0837692587326426 0.259068928728712 CTSL/ITGB1/MMP15/CST3 4 GO:0030890 positive regulation of B cell proliferation 4/742 42/18722 0.0837692587326426 0.259068928728712 SLC39A10/TFRC/MIF/CD81 4 GO:0045687 positive regulation of glial cell differentiation 4/742 42/18722 0.0837692587326426 0.259068928728712 SPINT1/DAG1/IL6ST/HES1 4 GO:0090317 negative regulation of intracellular protein transport 4/742 42/18722 0.0837692587326426 0.259068928728712 LMAN1/FERMT1/OS9/TXN 4 GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II 4/742 42/18722 0.0837692587326426 0.259068928728712 JUN/FOS/EGR1/GATA3 4 GO:0021885 forebrain cell migration 5/742 59/18722 0.0839089647704331 0.259068928728712 ADGRG1/LAMB1/RTN4/GLI3/RHOA 5 GO:0035306 positive regulation of dephosphorylation 5/742 59/18722 0.0839089647704331 0.259068928728712 SLC39A10/PPP1R15A/PPIA/CALM1/CALM2 5 GO:0043407 negative regulation of MAP kinase activity 5/742 59/18722 0.0839089647704331 0.259068928728712 DUSP1/CAV1/BMP7/NF1/PDCD4 5 GO:0051568 histone H3-K4 methylation 5/742 59/18722 0.0839089647704331 0.259068928728712 KMT2C/ASH1L/TET2/RTF1/GATA3 5 GO:2001258 negative regulation of cation channel activity 5/742 59/18722 0.0839089647704331 0.259068928728712 CAV1/ANK3/GSTO1/CALM1/CALM2 5 GO:0051051 negative regulation of transport 25/742 470/18722 0.0840514131212727 0.259346646357956 ITGAV/LMAN1/LRPAP1/ERP29/CAV1/SLC43A2/GJA1/ANK3/C4orf3/GABRE/GSTO1/TPR/FERMT1/ARL6IP5/FRMD4A/ANXA1/OS9/PPP1R9A/ERBB3/TXN/CALM1/VDAC1/CALM2/YWHAE/SDCBP 25 GO:0045930 negative regulation of mitotic cell cycle 14/742 235/18722 0.0851537795151845 0.262419751149112 EGFR/DUSP1/SOX4/RPL26/PRKDC/ZFP36L1/PPP1R10/BMP7/TPR/BTG1/DLG1/CTDSPL/BRD7/LCMT1 14 GO:0051251 positive regulation of lymphocyte activation 20/742 362/18722 0.0851843174495876 0.262419751149112 CD46/SLC39A10/TFRC/CAV1/MIF/SOX4/IL6ST/PRKDC/DPP4/CD81/ANXA1/GLI3/CD55/LAMP1/RIF1/GATA3/DOCK8/HES1/RHOA/IGF2 20 GO:0032103 positive regulation of response to external stimulus 23/742 427/18722 0.0852067370127885 0.262419751149112 EGFR/NEAT1/LRP1/GRN/APP/MET/CTSC/CADM1/IL6ST/PRKDC/NRP1/CALR/TMSB4X/CD81/LGMN/S100A9/PUM1/TPBG/LAMP1/NFKBIA/HSPB1/TGM2/PDCD4 23 GO:0030856 regulation of epithelial cell differentiation 10/742 154/18722 0.086120206433226 0.264902752042426 CAV1/ZFP36L1/BTG1/KIAA1109/ROCK1/NCOA3/SRSF6/GATA3/ID1/HES1 10 GO:0071326 cellular response to monosaccharide stimulus 10/742 154/18722 0.086120206433226 0.264902752042426 LRP1/SERPINF1/SOX4/DYNLL1/LRP5/IGF1R/KIF5B/TRA2B/HMGN3/PHPT1 10 GO:0046916 cellular transition metal ion homeostasis 8/742 115/18722 0.0865712932050171 0.266124572764645 SLC39A10/APP/FTH1/TFRC/ATP6AP1/S100A9/SLC40A1/SLC39A7 8 GO:0031669 cellular response to nutrient levels 13/742 215/18722 0.086689519910162 0.266322281316045 JUN/ATP2B1/HSPA5/SLC2A1/SLC38A2/CTSV/TNRC6A/FOLR1/EIF4G1/PMAIP1/HNRNPA1/LAMP2/EIF2AK4 13 GO:0042254 ribosome biogenesis 17/742 299/18722 0.0873267369403818 0.268113163757294 RPS21/RPLP0/RPL23A/RPS6/RPS16/RPL6/RPL14/RPL7/RPS25/RPL24/RPL26/PRKDC/NPM1/RPL3/DDX17/RPS17/RAN 17 GO:0031638 zymogen activation 5/742 60/18722 0.0887149392966168 0.270714463445622 CTSL/DHCR24/ENO1/ASPH/LGMN 5 GO:0042306 regulation of protein import into nucleus 5/742 60/18722 0.0887149392966168 0.270714463445622 CDH1/TPR/FERMT1/GLI3/RAN 5 GO:0030500 regulation of bone mineralization 6/742 78/18722 0.0888280975588958 0.270714463445622 FBN2/ATP2B1/BMP7/LTBP3/NOTUM/ATRAID 6 GO:0006606 protein import into nucleus 10/742 155/18722 0.0889827067949098 0.270714463445622 CDH1/RPL23/PPP1R10/TPR/FERMT1/GLI3/RANBP2/NFKBIA/KPNB1/RAN 10 GO:0045860 positive regulation of protein kinase activity 21/742 386/18722 0.0894622801280096 0.270714463445622 EGFR/DAG1/ERP29/IQGAP1/EGR1/FLT1/NPM1/ATP2B4/PRLR/MAGED1/DLG1/AKAP13/PPP1R9A/PPIA/ERBB3/TXN/CALM1/RHOA/IGF2/CALM2/CKS1B 21 GO:0009268 response to pH 4/742 43/18722 0.0896137033581683 0.270714463445622 SERPINF1/GJA1/SLC9A1/LGMN 4 GO:0016266 O-glycan processing 4/742 43/18722 0.0896137033581683 0.270714463445622 GALNT11/C1GALT1/C1GALT1C1/GXYLT1 4 GO:0030517 negative regulation of axon extension 4/742 43/18722 0.0896137033581683 0.270714463445622 SEMA6A/SEMA6D/RTN4/NRP1 4 GO:0035794 positive regulation of mitochondrial membrane permeability 4/742 43/18722 0.0896137033581683 0.270714463445622 HSPA1A/SLC9A1/NMT1/VDAC2 4 GO:0042181 ketone biosynthetic process 4/742 43/18722 0.0896137033581683 0.270714463445622 EGR1/TPI1/ADM/HSD17B1 4 GO:0045840 positive regulation of mitotic nuclear division 4/742 43/18722 0.0896137033581683 0.270714463445622 LRP5/PHIP/IGF2/ANAPC11 4 GO:0060443 mammary gland morphogenesis 4/742 43/18722 0.0896137033581683 0.270714463445622 CAV1/LRP5/GLI3/KDM5B 4 GO:1904591 positive regulation of protein import 4/742 43/18722 0.0896137033581683 0.270714463445622 CDH1/TPR/GLI3/RAN 4 GO:0031334 positive regulation of protein-containing complex assembly 14/742 237/18722 0.0897108806850393 0.270714463445622 AKAP9/IQGAP2/MET/CLIP1/TFRC/FERMT1/PFN1/HSPA1A/EIF4G1/DLG1/WASF2/HSPA1B/ARPC3/RHOA 14 GO:0033673 negative regulation of kinase activity 14/742 237/18722 0.0897108806850393 0.270714463445622 PLEC/GADD45B/DUSP1/CAV1/LRP5/NPM1/BMP7/NR2F2/NF1/GNAQ/PPIA/HSPB1/ADAR/PDCD4 14 GO:0034698 response to gonadotropin 3/742 27/18722 0.0897368835859784 0.270714463445622 TGFBR3/CTSV/POR 3 GO:0042403 thyroid hormone metabolic process 3/742 27/18722 0.0897368835859784 0.270714463445622 CPQ/GATA3/CGA 3 GO:1903421 regulation of synaptic vesicle recycling 3/742 27/18722 0.0897368835859784 0.270714463445622 ROCK1/VAMP2/CALM1 3 GO:1904357 negative regulation of telomere maintenance via telomere lengthening 3/742 27/18722 0.0897368835859784 0.270714463445622 HNRNPA1/PARP1/HNRNPC 3 GO:0018107 peptidyl-threonine phosphorylation 8/742 116/18722 0.0899443605509628 0.270714463445622 APP/PRKDC/BMP7/EIF4G1/ROCK1/CALM1/CALM2/CSNK2B 8 GO:0030326 embryonic limb morphogenesis 8/742 116/18722 0.0899443605509628 0.270714463445622 FBN2/PBX1/LRP5/FRAS1/BMP7/GLI3/NIPBL/TMEM107 8 GO:0035113 embryonic appendage morphogenesis 8/742 116/18722 0.0899443605509628 0.270714463445622 FBN2/PBX1/LRP5/FRAS1/BMP7/GLI3/NIPBL/TMEM107 8 GO:0014909 smooth muscle cell migration 7/742 97/18722 0.0903562639902693 0.270714463445622 LRP1/IQGAP1/SEMA6D/ADAMTS1/NRP1/GNA12/RHOA 7 GO:0070167 regulation of biomineral tissue development 7/742 97/18722 0.0903562639902693 0.270714463445622 FBN2/ATP2B1/BMP7/LTBP3/ROCK1/NOTUM/ATRAID 7 GO:0043393 regulation of protein binding 12/742 196/18722 0.09048431581179 0.270714463445622 LRP1/APP/LRPAP1/CAV1/TGFBR3/NRP1/PTPRF/ROCK1/TCF7L2/ID1/RAN/CDC42 12 GO:0071674 mononuclear cell migration 12/742 196/18722 0.09048431581179 0.270714463445622 APP/PLEC/DUSP1/FLT1/CALR/MIA3/ANXA1/LGMN/GATA3/DOCK8/CDC42/RHOA 12 GO:0005513 detection of calcium ion 2/742 13/18722 0.0916741311577094 0.270714463445622 CALM1/CALM2 2 GO:0008298 intracellular mRNA localization 2/742 13/18722 0.0916741311577094 0.270714463445622 ZFP36L1/DHX36 2 GO:0009437 carnitine metabolic process 2/742 13/18722 0.0916741311577094 0.270714463445622 POR/CROT 2 GO:0009650 UV protection 2/742 13/18722 0.0916741311577094 0.270714463445622 SDF4/GPX1 2 GO:0010635 regulation of mitochondrial fusion 2/742 13/18722 0.0916741311577094 0.270714463445622 TFRC/HUWE1 2 GO:0010745 negative regulation of macrophage derived foam cell differentiation 2/742 13/18722 0.0916741311577094 0.270714463445622 ITGAV/NFKBIA 2 GO:0010917 negative regulation of mitochondrial membrane potential 2/742 13/18722 0.0916741311577094 0.270714463445622 ARL6IP5/PMAIP1 2 GO:0010960 magnesium ion homeostasis 2/742 13/18722 0.0916741311577094 0.270714463445622 EGFR/ANK3 2 GO:0015809 arginine transport 2/742 13/18722 0.0916741311577094 0.270714463445622 SLC38A9/CLN3 2 GO:0016246 RNA interference 2/742 13/18722 0.0916741311577094 0.270714463445622 CELF1/ADAR 2 GO:0021514 ventral spinal cord interneuron differentiation 2/742 13/18722 0.0916741311577094 0.270714463445622 LMO4/GLI3 2 GO:0021554 optic nerve development 2/742 13/18722 0.0916741311577094 0.270714463445622 RPL24/GLI3 2 GO:0021819 layer formation in cerebral cortex 2/742 13/18722 0.0916741311577094 0.270714463445622 ADGRG1/GLI3 2 GO:0034112 positive regulation of homotypic cell-cell adhesion 2/742 13/18722 0.0916741311577094 0.270714463445622 IL6ST/ANK3 2 GO:0035745 T-helper 2 cell cytokine production 2/742 13/18722 0.0916741311577094 0.270714463445622 CD81/GATA3 2 GO:0042769 DNA damage response, detection of DNA damage 2/742 13/18722 0.0916741311577094 0.270714463445622 SOX4/PARP1 2 GO:0044794 positive regulation by host of viral process 2/742 13/18722 0.0916741311577094 0.270714463445622 STOM/CFL1 2 GO:0048012 hepatocyte growth factor receptor signaling pathway 2/742 13/18722 0.0916741311577094 0.270714463445622 MET/NRP1 2 GO:0048711 positive regulation of astrocyte differentiation 2/742 13/18722 0.0916741311577094 0.270714463445622 IL6ST/HES1 2 GO:0051451 myoblast migration 2/742 13/18722 0.0916741311577094 0.270714463445622 ANXA1/ROCK1 2 GO:0051956 negative regulation of amino acid transport 2/742 13/18722 0.0916741311577094 0.270714463445622 SLC43A2/ARL6IP5 2 GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 2/742 13/18722 0.0916741311577094 0.270714463445622 TNRC6A/TNRC6B 2 GO:0060347 heart trabecula formation 2/742 13/18722 0.0916741311577094 0.270714463445622 TGFBR3/ADAMTS1 2 GO:0060707 trophoblast giant cell differentiation 2/742 13/18722 0.0916741311577094 0.270714463445622 NR2F2/HECTD1 2 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 2/742 13/18722 0.0916741311577094 0.270714463445622 EGR1/CITED2 2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway 2/742 13/18722 0.0916741311577094 0.270714463445622 HSPA1A/HSPA1B 2 GO:0070486 leukocyte aggregation 2/742 13/18722 0.0916741311577094 0.270714463445622 BMP7/S100A9 2 GO:0090161 Golgi ribbon formation 2/742 13/18722 0.0916741311577094 0.270714463445622 TRIP11/GCC2 2 GO:0098840 protein transport along microtubule 2/742 13/18722 0.0916741311577094 0.270714463445622 KIF5B/HSPB1 2 GO:0099118 microtubule-based protein transport 2/742 13/18722 0.0916741311577094 0.270714463445622 KIF5B/HSPB1 2 GO:1900272 negative regulation of long-term synaptic potentiation 2/742 13/18722 0.0916741311577094 0.270714463445622 APP/PPP1R9A 2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 2/742 13/18722 0.0916741311577094 0.270714463445622 PMAIP1/TIMP3 2 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance 2/742 13/18722 0.0916741311577094 0.270714463445622 NRP2/NRP1 2 GO:1903054 negative regulation of extracellular matrix organization 2/742 13/18722 0.0916741311577094 0.270714463445622 DPP4/CST3 2 GO:1904925 positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization 2/742 13/18722 0.0916741311577094 0.270714463445622 VPS13C/HUWE1 2 GO:1905269 positive regulation of chromatin organization 2/742 13/18722 0.0916741311577094 0.270714463445622 MPHOSPH8/TPR 2 GO:2000551 regulation of T-helper 2 cell cytokine production 2/742 13/18722 0.0916741311577094 0.270714463445622 CD81/GATA3 2 GO:0002696 positive regulation of leukocyte activation 22/742 409/18722 0.0916812342802685 0.270714463445622 CD46/SLC39A10/JUND/CTSC/TFRC/CAV1/MIF/SOX4/IL6ST/PRKDC/DPP4/CD81/ANXA1/GLI3/CD55/LAMP1/RIF1/GATA3/DOCK8/HES1/RHOA/IGF2 22 GO:0009267 cellular response to starvation 10/742 156/18722 0.0919018524740342 0.271203794039265 JUN/HSPA5/SLC2A1/SLC38A2/CTSV/TNRC6A/PMAIP1/HNRNPA1/LAMP2/EIF2AK4 10 GO:0060420 regulation of heart growth 6/742 79/18722 0.0930934999422254 0.274556352068414 TGFBR3/GJA1/DUSP6/DUSP9/CITED2/YY1 6 GO:1904356 regulation of telomere maintenance via telomere lengthening 5/742 61/18722 0.0936608431222964 0.276064776267389 HNRNPA1/DHX36/PARP1/HNRNPC/CCT3 5 GO:0043502 regulation of muscle adaptation 7/742 98/18722 0.0941760902970164 0.277417940409816 DAG1/IL6ST/ATP2B4/SLC9A1/ROCK1/PARP1/YY1 7 GO:0043405 regulation of MAP kinase activity 11/742 177/18722 0.0942556645151552 0.277486878846762 EGFR/ERP29/DUSP1/CAV1/IQGAP1/FLT1/BMP7/NF1/MAGED1/AKAP13/PDCD4 11 GO:0008544 epidermis development 18/742 324/18722 0.0947236217972947 0.278698446503059 EGFR/LAMA5/SVEP1/LGR5/PLEC/LGR4/DSP/ZFP36L1/FERMT1/ANXA1/YBX1/ROCK1/TRIOBP/ST14/NCOA3/ASAH1/SRSF6/HES1 18 GO:1902600 proton transmembrane transport 10/742 157/18722 0.0948775819621685 0.27898527076971 COX6A1/ATP6AP1/TMSB4X/SLC9A1/ACTN4/ATP1A1/ATP6V1B1/ATP6V0B/UQCRH/COX5A 10 GO:0005978 glycogen biosynthetic process 4/742 44/18722 0.0956482512249465 0.27991846033841 AGL/PTGES3/IGF2/UGP2 4 GO:0009250 glucan biosynthetic process 4/742 44/18722 0.0956482512249465 0.27991846033841 AGL/PTGES3/IGF2/UGP2 4 GO:0021517 ventral spinal cord development 4/742 44/18722 0.0956482512249465 0.27991846033841 SOX4/LMO4/ISL1/GLI3 4 GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT 4/742 44/18722 0.0956482512249465 0.27991846033841 CSH1/PRLR/IL10RB/HES1 4 GO:0048806 genitalia development 4/742 44/18722 0.0956482512249465 0.27991846033841 LRP2/LGR4/DHCR24/NIPBL 4 GO:0050999 regulation of nitric-oxide synthase activity 4/742 44/18722 0.0956482512249465 0.27991846033841 EGFR/CAV1/ATP2B4/CALM1 4 GO:1903214 regulation of protein targeting to mitochondrion 4/742 44/18722 0.0956482512249465 0.27991846033841 LMAN1/HUWE1/LEPROT/UBE2L3 4 GO:1903573 negative regulation of response to endoplasmic reticulum stress 4/742 44/18722 0.0956482512249465 0.27991846033841 HSPA5/UFL1/PPP1R15A/HSPA1A 4 GO:2001020 regulation of response to DNA damage stimulus 13/742 219/18722 0.0965387905245553 0.282357386140499 EGFR/TPT1/FUS/MIF/RPL26/PRKDC/PPP1R10/NPM1/PMAIP1/RIF1/DDX5/IER3/PARP1 13 GO:0045446 endothelial cell differentiation 8/742 118/18722 0.0969152432768001 0.2832907111168 MET/NRP1/NR2F2/FSTL1/BTG1/ROCK1/GPX1/ID1 8 GO:0000423 mitophagy 3/742 28/18722 0.0976831582056925 0.283855765609483 VPS13C/HUWE1/VDAC1 3 GO:0001945 lymph vessel development 3/742 28/18722 0.0976831582056925 0.283855765609483 SVEP1/NR2F2/PTPN14 3 GO:0006829 zinc ion transport 3/742 28/18722 0.0976831582056925 0.283855765609483 SLC39A10/SLC39A7/SLC39A1 3 GO:0032801 receptor catabolic process 3/742 28/18722 0.0976831582056925 0.283855765609483 RNF43/ZNRF3/LGMN 3 GO:0060325 face morphogenesis 3/742 28/18722 0.0976831582056925 0.283855765609483 ANKRD11/NIPBL/ARID5B 3 GO:0060765 regulation of androgen receptor signaling pathway 3/742 28/18722 0.0976831582056925 0.283855765609483 NCOR1/FOXP1/DDX5 3 GO:0080111 DNA demethylation 3/742 28/18722 0.0976831582056925 0.283855765609483 USP9X/TET2/GATA3 3 GO:0086011 membrane repolarization during action potential 3/742 28/18722 0.0976831582056925 0.283855765609483 CAV1/ATP1A1/YWHAE 3 GO:1903779 regulation of cardiac conduction 3/742 28/18722 0.0976831582056925 0.283855765609483 ATP2B1/ATP2B4/GJA5 3 GO:1990776 response to angiotensin 3/742 28/18722 0.0976831582056925 0.283855765609483 CAV1/IQGAP1/ROCK1 3 GO:0055076 transition metal ion homeostasis 9/742 138/18722 0.0979726246509112 0.284186042503587 SLC39A10/APP/FTH1/TFRC/ATP6AP1/S100A9/SLC40A1/SLC39A7/EPAS1 9 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 9/742 138/18722 0.0979726246509112 0.284186042503587 HSPA5/MYCBP2/CAV1/RPS2/NPM1/HUWE1/SKP1/UBE2L3/UBE2C 9 GO:0003300 cardiac muscle hypertrophy 7/742 99/18722 0.0980844539410152 0.284186042503587 IL6ST/ATP2B4/SLC9A1/AKAP13/ROCK1/PARP1/YY1 7 GO:0060291 long-term synaptic potentiation 7/742 99/18722 0.0980844539410152 0.284186042503587 APP/MME/LGMN/NCSTN/PPP1R9A/VAMP2/EIF2AK4 7 GO:0110149 regulation of biomineralization 7/742 99/18722 0.0980844539410152 0.284186042503587 FBN2/ATP2B1/BMP7/LTBP3/ROCK1/NOTUM/ATRAID 7 GO:0009311 oligosaccharide metabolic process 5/742 62/18722 0.0987447860772163 0.285596746616773 GAA/MANBA/MOGS/FUT8/HEXB 5 GO:0048002 antigen processing and presentation of peptide antigen 5/742 62/18722 0.0987447860772163 0.285596746616773 CTSL/CTSD/CTSV/CALR/LGMN 5 GO:0060113 inner ear receptor cell differentiation 5/742 62/18722 0.0987447860772163 0.285596746616773 TRIP11/NAGLU/TRIOBP/IFT27/HES1 5 GO:0002064 epithelial cell development 13/742 220/18722 0.099103882540437 0.28646763004667 ADAMTSL4/MET/SPINT2/PLEC/IQGAP1/ATRX/IL6ST/CDK6/FAT1/ROCK1/TRIOBP/ST14/GPX1 13 GO:0006813 potassium ion transport 14/742 241/18722 0.0992764428423081 0.286798612655557 AKAP9/ITGB1/KCNN4/SLC12A9/CAV1/ANK3/GJA5/SLC9A1/KIF5B/DLG1/ATP1A1/VAMP2/FXYD3/YWHAE 14 GO:0043410 positive regulation of MAPK cascade 25/742 480/18722 0.100455994044038 0.290036592973437 EGFR/LRP1/APP/GADD45B/ERP29/IQGAP1/MIF/FLT1/ATP6AP1/IGF1R/NRP1/ARL6IP5/CD81/MYDGF/MAGED1/AKAP13/ROCK1/EMC10/TPBG/PPIA/RB1CC1/GADD45G/CDC42/IGF2/SDCBP 25 GO:0071902 positive regulation of protein serine/threonine kinase activity 12/742 200/18722 0.101160522531797 0.291900105903667 EGFR/ERP29/IQGAP1/FLT1/ATP2B4/MAGED1/AKAP13/CALM1/RHOA/IGF2/CALM2/CKS1B 12 GO:0030216 keratinocyte differentiation 9/742 139/18722 0.101298806637442 0.291958054135918 PLEC/DSP/ZFP36L1/ANXA1/ROCK1/ST14/NCOA3/ASAH1/SRSF6 9 GO:0045598 regulation of fat cell differentiation 9/742 139/18722 0.101298806637442 0.291958054135918 ZFP36L1/LRP5/BMP7/ANKRD26/CDS1/DDIT3/GATA3/ADIRF/HES1 9 GO:0030835 negative regulation of actin filament depolymerization 4/742 45/18722 0.101868469486316 0.292805761958541 SPTAN1/SPTBN1/TRIOBP/CAPZB 4 GO:0035305 negative regulation of dephosphorylation 4/742 45/18722 0.101868469486316 0.292805761958541 BOD1L1/PPP1R15A/ROCK1/YWHAE 4 GO:0045933 positive regulation of muscle contraction 4/742 45/18722 0.101868469486316 0.292805761958541 GSTO1/ENO1/ATP1A1/RHOA 4 GO:1901985 positive regulation of protein acetylation 4/742 45/18722 0.101868469486316 0.292805761958541 SOX4/ISL1/BRD7/GATA3 4 GO:0030641 regulation of cellular pH 6/742 81/18722 0.101948564892448 0.292805761958541 GRN/ATP6AP1/SLC9A1/ATP6AP2/TMEM165/CLN3 6 GO:0051817 modulation of process of other organism involved in symbiotic interaction 6/742 81/18722 0.101948564892448 0.292805761958541 JUN/DAG1/STOM/CFL1/EIF2AK4/SERPINB9 6 GO:0044728 DNA methylation or demethylation 7/742 100/18722 0.102080765634165 0.293015097171861 FOS/ATRX/MPHOSPH8/USP9X/TET2/GATA3/PARP1 7 GO:0015698 inorganic anion transport 11/742 180/18722 0.102891532289777 0.29308512485884 SLC26A2/CLDN4/SLC22A11/SLC12A9/SLC13A4/GABRE/CLIC3/PCYOX1/VDAC1/FXYD3/VDAC2 11 GO:0015833 peptide transport 15/742 264/18722 0.103836666210022 0.29308512485884 EGFR/LRP1/SOX4/GJA1/DPP4/DYNLL1/LRP5/ISL1/ANXA1/KIF5B/TCF7L2/SYT7/SLC16A1/HMGN3/PHPT1 15 GO:0009952 anterior/posterior pattern specification 12/742 201/18722 0.103942562270121 0.29308512485884 WLS/BPTF/PBX1/PRKDC/LRP5/NR2F2/GLI3/ATP6AP2/PGAP1/DDIT3/HES1/YY1 12 GO:0050854 regulation of antigen receptor-mediated signaling pathway 5/742 63/18722 0.103964701065966 0.29308512485884 SLC39A10/KCNN4/CD81/FOXP1/PHPT1 5 GO:1902373 negative regulation of mRNA catabolic process 5/742 63/18722 0.103964701065966 0.29308512485884 FUS/YBX1/LARP1/CIRBP/HNRNPC 5 GO:1904589 regulation of protein import 5/742 63/18722 0.103964701065966 0.29308512485884 CDH1/TPR/FERMT1/GLI3/RAN 5 GO:0002761 regulation of myeloid leukocyte differentiation 8/742 120/18722 0.104183694321557 0.29308512485884 JUN/FBN1/FOS/ZFP36L1/ATP6AP1/ESRRA/CDK6/FOXP1 8 GO:0072655 establishment of protein localization to mitochondrion 8/742 120/18722 0.104183694321557 0.29308512485884 LMAN1/NMT1/DDIT3/CALM1/HUWE1/BCAP31/LEPROT/UBE2L3 8 GO:0000054 ribosomal subunit export from nucleus 2/742 14/18722 0.104241004934612 0.29308512485884 NPM1/RAN 2 GO:0002091 negative regulation of receptor internalization 2/742 14/18722 0.104241004934612 0.29308512485884 LRPAP1/SDCBP 2 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis 2/742 14/18722 0.104241004934612 0.29308512485884 TRIP11/SERPINH1 2 GO:0006465 signal peptide processing 2/742 14/18722 0.104241004934612 0.29308512485884 SPCS2/HM13 2 GO:0006521 regulation of cellular amino acid metabolic process 2/742 14/18722 0.104241004934612 0.29308512485884 ATP2B4/CLN3 2 GO:0006999 nuclear pore organization 2/742 14/18722 0.104241004934612 0.29308512485884 RTN4/TPR 2 GO:0033750 ribosome localization 2/742 14/18722 0.104241004934612 0.29308512485884 NPM1/RAN 2 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway 2/742 14/18722 0.104241004934612 0.29308512485884 LRP1/PTPN12 2 GO:0036295 cellular response to increased oxygen levels 2/742 14/18722 0.104241004934612 0.29308512485884 CAV1/ATP6AP1 2 GO:0038166 angiotensin-activated signaling pathway 2/742 14/18722 0.104241004934612 0.29308512485884 CAV1/ROCK1 2 GO:0042415 norepinephrine metabolic process 2/742 14/18722 0.104241004934612 0.29308512485884 GATA3/EPAS1 2 GO:0044764 multi-organism cellular process 2/742 14/18722 0.104241004934612 0.29308512485884 CTSL/CAV1 2 GO:0045837 negative regulation of membrane potential 2/742 14/18722 0.104241004934612 0.29308512485884 ARL6IP5/PMAIP1 2 GO:0045989 positive regulation of striated muscle contraction 2/742 14/18722 0.104241004934612 0.29308512485884 GSTO1/ATP1A1 2 GO:0046479 glycosphingolipid catabolic process 2/742 14/18722 0.104241004934612 0.29308512485884 HEXA/HEXB 2 GO:0046655 folic acid metabolic process 2/742 14/18722 0.104241004934612 0.29308512485884 SLC19A1/FOLR1 2 GO:0047484 regulation of response to osmotic stress 2/742 14/18722 0.104241004934612 0.29308512485884 CLN3/EFHD1 2 GO:0051645 Golgi localization 2/742 14/18722 0.104241004934612 0.29308512485884 ARHGAP21/CDC42 2 GO:0070141 response to UV-A 2/742 14/18722 0.104241004934612 0.29308512485884 EGFR/MME 2 GO:0071285 cellular response to lithium ion 2/742 14/18722 0.104241004934612 0.29308512485884 CDH1/CALR 2 GO:0071481 cellular response to X-ray 2/742 14/18722 0.104241004934612 0.29308512485884 NIPBL/GATA3 2 GO:0072531 pyrimidine-containing compound transmembrane transport 2/742 14/18722 0.104241004934612 0.29308512485884 SLC25A36/SLC19A3 2 GO:1902036 regulation of hematopoietic stem cell differentiation 2/742 14/18722 0.104241004934612 0.29308512485884 N4BP2L2/PRKDC 2 GO:1903894 regulation of IRE1-mediated unfolded protein response 2/742 14/18722 0.104241004934612 0.29308512485884 HSPA5/UFL1 2 GO:1904152 regulation of retrograde protein transport, ER to cytosol 2/742 14/18722 0.104241004934612 0.29308512485884 OS9/BCAP31 2 GO:1904923 regulation of autophagy of mitochondrion in response to mitochondrial depolarization 2/742 14/18722 0.104241004934612 0.29308512485884 VPS13C/HUWE1 2 GO:1905049 negative regulation of metallopeptidase activity 2/742 14/18722 0.104241004934612 0.29308512485884 LRP1/TIMP3 2 GO:2001171 positive regulation of ATP biosynthetic process 2/742 14/18722 0.104241004934612 0.29308512485884 TMSB4X/ENO1 2 GO:0006479 protein methylation 11/742 181/18722 0.105870347109258 0.295903747135823 ATRX/BRD4/KMT2C/BTG1/ASH1L/TET2/NSD1/RIF1/RTF1/GATA3/LCMT1 11 GO:0008213 protein alkylation 11/742 181/18722 0.105870347109258 0.295903747135823 ATRX/BRD4/KMT2C/BTG1/ASH1L/TET2/NSD1/RIF1/RTF1/GATA3/LCMT1 11 GO:0002360 T cell lineage commitment 3/742 29/18722 0.105902393711768 0.295903747135823 CTSL/PRKDC/RHOA 3 GO:0034067 protein localization to Golgi apparatus 3/742 29/18722 0.105902393711768 0.295903747135823 GCC2/VPS13C/OBSL1 3 GO:0035066 positive regulation of histone acetylation 3/742 29/18722 0.105902393711768 0.295903747135823 ISL1/BRD7/GATA3 3 GO:0040018 positive regulation of multicellular organism growth 3/742 29/18722 0.105902393711768 0.295903747135823 NIPBL/CELF1/IGF2 3 GO:0048679 regulation of axon regeneration 3/742 29/18722 0.105902393711768 0.295903747135823 LRP1/GRN/PTPRF 3 GO:0050686 negative regulation of mRNA processing 3/742 29/18722 0.105902393711768 0.295903747135823 NPM1/SRSF7/SRSF6 3 GO:0070979 protein K11-linked ubiquitination 3/742 29/18722 0.105902393711768 0.295903747135823 ANAPC11/UBE2L3/UBE2C 3 GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 3/742 29/18722 0.105902393711768 0.295903747135823 MIF/RPL26/EIF5A 3 GO:2000406 positive regulation of T cell migration 3/742 29/18722 0.105902393711768 0.295903747135823 APP/DOCK8/RHOA 3 GO:0060395 SMAD protein signal transduction 6/742 82/18722 0.10653604039904 0.297505957926092 JUN/FOS/LRP1/BMP7/SPTBN1/PARP1 6 GO:0043244 regulation of protein-containing complex disassembly 8/742 121/18722 0.107928519583392 0.301224229797717 SPTAN1/IGF1R/SPTBN1/TRIOBP/CLN3/DSTN/CAPZB/EIF5A 8 GO:0016571 histone methylation 9/742 141/18722 0.108142624455082 0.301325105659506 ATRX/BRD4/KMT2C/ASH1L/TET2/NSD1/RIF1/RTF1/GATA3 9 GO:0031018 endocrine pancreas development 4/742 46/18722 0.108269648288588 0.301325105659506 SOX4/ANXA1/CDK6/HES1 4 GO:0055010 ventricular cardiac muscle tissue morphogenesis 4/742 46/18722 0.108269648288588 0.301325105659506 LRP2/TGFBR3/DSP/ISL1 4 GO:0060976 coronary vasculature development 4/742 46/18722 0.108269648288588 0.301325105659506 LRP2/ADAMTS6/TGFBR3/NRP1 4 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 4/742 46/18722 0.108269648288588 0.301325105659506 EGFR/ADAMTS1/ANXA1/EIF4G1 4 GO:0006749 glutathione metabolic process 5/742 64/18722 0.109318352309822 0.303730405180269 GSTO1/ARL6IP5/CLIC3/GPX1/GPX4 5 GO:0098930 axonal transport 5/742 64/18722 0.109318352309822 0.303730405180269 ARMCX3/DYNC1H1/DST/KIF5B/HSPB1 5 GO:1903018 regulation of glycoprotein metabolic process 5/742 64/18722 0.109318352309822 0.303730405180269 ITM2B/TMEM59/NCSTN/CST3/TCF7L2 5 GO:0046651 lymphocyte proliferation 16/742 288/18722 0.110196490345297 0.305998123836857 CD46/SLC39A10/RPS6/TFRC/MIF/IL6ST/DLG5/CD81/ANXA1/NCSTN/DLG1/CD55/PURA/DOCK8/HES1/IGF2 16 GO:0014897 striated muscle hypertrophy 7/742 102/18722 0.110334501261107 0.306209233837005 IL6ST/ATP2B4/SLC9A1/AKAP13/ROCK1/PARP1/YY1 7 GO:0018108 peptidyl-tyrosine phosphorylation 20/742 375/18722 0.110494161802687 0.306480156824972 EGFR/EFEMP1/APP/MET/CAV1/IQGAP1/MIF/IL6ST/EPHB4/CSH1/FLT1/IGF1R/NRP1/ISL1/PRLR/CD81/ERBB3/BAZ1B/HES1/IGF2 20 GO:0050867 positive regulation of cell activation 22/742 420/18722 0.112475402463772 0.311800498412477 CD46/SLC39A10/JUND/CTSC/TFRC/CAV1/MIF/SOX4/IL6ST/PRKDC/DPP4/CD81/ANXA1/GLI3/CD55/LAMP1/RIF1/GATA3/DOCK8/HES1/RHOA/IGF2 22 GO:0018205 peptidyl-lysine modification 20/742 376/18722 0.112615717466411 0.312014382660725 ATRX/SOX4/EGR1/ISL1/POR/BRD4/KMT2C/ASH1L/RANBP2/NCOA3/TET2/NSD1/RIF1/BRD7/RTF1/GATA3/USP22/PHF20/TGM2/MORF4L2 20 GO:0061025 membrane fusion 10/742 163/18722 0.113912900938064 0.313449344693278 CTSL/SPESP1/EEA1/FOLR1/ANXA1/KIF5B/SYT7/VAMP2/HUWE1/CLN3 10 GO:0000132 establishment of mitotic spindle orientation 3/742 30/18722 0.114381456926175 0.313449344693278 ITGB1/GJA1/DYNLT1 3 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 3/742 30/18722 0.114381456926175 0.313449344693278 GSTO1/CALM1/CALM2 3 GO:0031571 mitotic G1 DNA damage checkpoint signaling 3/742 30/18722 0.114381456926175 0.313449344693278 SOX4/RPL26/PRKDC 3 GO:0044788 modulation by host of viral process 3/742 30/18722 0.114381456926175 0.313449344693278 STOM/CFL1/EIF2AK4 3 GO:0045940 positive regulation of steroid metabolic process 3/742 30/18722 0.114381456926175 0.313449344693278 POR/ADM/CGA 3 GO:0045948 positive regulation of translational initiation 3/742 30/18722 0.114381456926175 0.313449344693278 PPP1R15A/EIF2AK4/LARP1 3 GO:0060351 cartilage development involved in endochondral bone morphogenesis 3/742 30/18722 0.114381456926175 0.313449344693278 TRIP11/SERPINH1/POR 3 GO:0061384 heart trabecula morphogenesis 3/742 30/18722 0.114381456926175 0.313449344693278 TGFBR3/ADAMTS1/BMP7 3 GO:0070229 negative regulation of lymphocyte apoptotic process 3/742 30/18722 0.114381456926175 0.313449344693278 SLC39A10/FOXP1/DOCK8 3 GO:0090314 positive regulation of protein targeting to membrane 3/742 30/18722 0.114381456926175 0.313449344693278 TCAF1/ANK3/STOM 3 GO:1903019 negative regulation of glycoprotein metabolic process 3/742 30/18722 0.114381456926175 0.313449344693278 ITM2B/TMEM59/CST3 3 GO:1903579 negative regulation of ATP metabolic process 3/742 30/18722 0.114381456926175 0.313449344693278 NCOR1/PARP1/RHOA 3 GO:0030004 cellular monovalent inorganic cation homeostasis 7/742 103/18722 0.114590376481273 0.313449344693278 GRN/ATP6AP1/SLC9A1/ATP6AP2/ATP1A1/TMEM165/CLN3 7 GO:0045639 positive regulation of myeloid cell differentiation 7/742 103/18722 0.114590376481273 0.313449344693278 JUN/FOS/PRKDC/ZFP36L1/ATP6AP1/HSPA1A/HSPA1B 7 GO:0050773 regulation of dendrite development 7/742 103/18722 0.114590376481273 0.313449344693278 IQGAP1/BMP7/CUX1/DHX36/OBSL1/ID1/RHOA 7 GO:0003170 heart valve development 5/742 65/18722 0.114803343709608 0.313449344693278 SOX4/GJA5/ROCK1/HECTD1/GATA3 5 GO:0045453 bone resorption 5/742 65/18722 0.114803343709608 0.313449344693278 EGFR/TFRC/ATP6AP1/NF1/LTBP3 5 GO:0045682 regulation of epidermis development 5/742 65/18722 0.114803343709608 0.313449344693278 ZFP36L1/ROCK1/NCOA3/SRSF6/HES1 5 GO:0060389 pathway-restricted SMAD protein phosphorylation 5/742 65/18722 0.114803343709608 0.313449344693278 LRP1/TGFBR3/BMP7/CSNK2B/SDCBP 5 GO:0070936 protein K48-linked ubiquitination 5/742 65/18722 0.114803343709608 0.313449344693278 TTC3/TRIM44/PPIA/SKP1/UBE2C 5 GO:0071677 positive regulation of mononuclear cell migration 5/742 65/18722 0.114803343709608 0.313449344693278 APP/CALR/LGMN/DOCK8/RHOA 5 GO:0016574 histone ubiquitination 4/742 47/18722 0.114846824675067 0.313449344693278 DDB1/HUWE1/USP22/SKP1 4 GO:0019884 antigen processing and presentation of exogenous antigen 4/742 47/18722 0.114846824675067 0.313449344693278 CTSL/CTSD/CTSV/LGMN 4 GO:0045911 positive regulation of DNA recombination 4/742 47/18722 0.114846824675067 0.313449344693278 FUS/TFRC/RIF1/PARP1 4 GO:0046677 response to antibiotic 4/742 47/18722 0.114846824675067 0.313449344693278 HSPA5/RPL23/SLC9A1/KDM5B 4 GO:0072583 clathrin-dependent endocytosis 4/742 47/18722 0.114846824675067 0.313449344693278 AAK1/CANX/CLTC/CLTA 4 GO:0048285 organelle fission 25/742 488/18722 0.114977149736433 0.313631761290988 RPL24/DUSP1/ATRX/LRP5/BMP7/TPR/CALR/HSPA1A/PHIP/NIPBL/HSPA1B/RAD50/OBSL1/KPNB1/RAN/CDC42/NEK6/RHOA/IGF2/RAB11A/ANAPC11/UBE2C/RANBP1/LCMT1/CCNE1 25 GO:0062013 positive regulation of small molecule metabolic process 9/742 143/18722 0.115239611187681 0.314174215931095 APP/POR/TMSB4X/ANXA1/ENO1/DDB1/PMAIP1/ADM/IGF2 9 GO:0002088 lens development in camera-type eye 6/742 84/18722 0.116024600042477 0.314590893462634 CRYBG3/FAT1/DLG1/KDM5B/CITED2/GATA3 6 GO:0097061 dendritic spine organization 6/742 84/18722 0.116024600042477 0.314590893462634 IGF1R/LGMN/PPP1R9A/CFL1/DHX36/CDC42 6 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 6/742 84/18722 0.116024600042477 0.314590893462634 SOX4/RPL26/PRKDC/DLG1/CTDSPL/BRD7 6 GO:0006268 DNA unwinding involved in DNA replication 2/742 15/18722 0.117239237826864 0.314590893462634 PURA/HMGA1 2 GO:0006704 glucocorticoid biosynthetic process 2/742 15/18722 0.117239237826864 0.314590893462634 ATP1A1/CYP11A1 2 GO:0032328 alanine transport 2/742 15/18722 0.117239237826864 0.314590893462634 SLC3A2/SLC38A2 2 GO:0032354 response to follicle-stimulating hormone 2/742 15/18722 0.117239237826864 0.314590893462634 TGFBR3/POR 2 GO:0032488 Cdc42 protein signal transduction 2/742 15/18722 0.117239237826864 0.314590893462634 NRP1/CDC42 2 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway 2/742 15/18722 0.117239237826864 0.314590893462634 ISL1/LBH 2 GO:0036376 sodium ion export across plasma membrane 2/742 15/18722 0.117239237826864 0.314590893462634 SLC9A1/ATP1A1 2 GO:0042159 lipoprotein catabolic process 2/742 15/18722 0.117239237826864 0.314590893462634 CTSD/NOTUM 2 GO:0042994 cytoplasmic sequestering of transcription factor 2/742 15/18722 0.117239237826864 0.314590893462634 TMSB4X/NFKBIA 2 GO:0045064 T-helper 2 cell differentiation 2/742 15/18722 0.117239237826864 0.314590893462634 ANXA1/GATA3 2 GO:0045176 apical protein localization 2/742 15/18722 0.117239237826864 0.314590893462634 DLG5/JAM3 2 GO:0051938 L-glutamate import 2/742 15/18722 0.117239237826864 0.314590893462634 ITGB1/ARL6IP5 2 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 2/742 15/18722 0.117239237826864 0.314590893462634 TNRC6A/TNRC6B 2 GO:0060413 atrial septum morphogenesis 2/742 15/18722 0.117239237826864 0.314590893462634 SOX4/ISL1 2 GO:0060766 negative regulation of androgen receptor signaling pathway 2/742 15/18722 0.117239237826864 0.314590893462634 NCOR1/FOXP1 2 GO:0070207 protein homotrimerization 2/742 15/18722 0.117239237826864 0.314590893462634 MIF/SLC1A5 2 GO:0070831 basement membrane assembly 2/742 15/18722 0.117239237826864 0.314590893462634 LAMB1/DAG1 2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum 2/742 15/18722 0.117239237826864 0.314590893462634 CD81/BCAP31 2 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus 2/742 15/18722 0.117239237826864 0.314590893462634 NPM1/RAN 2 GO:0071474 cellular hyperosmotic response 2/742 15/18722 0.117239237826864 0.314590893462634 SLC2A1/EFHD1 2 GO:0071871 response to epinephrine 2/742 15/18722 0.117239237826864 0.314590893462634 ATP2B4/SLC9A1 2 GO:0072224 metanephric glomerulus development 2/742 15/18722 0.117239237826864 0.314590893462634 LGR4/EGR1 2 GO:0098712 L-glutamate import across plasma membrane 2/742 15/18722 0.117239237826864 0.314590893462634 ITGB1/ARL6IP5 2 GO:1900029 positive regulation of ruffle assembly 2/742 15/18722 0.117239237826864 0.314590893462634 PFN1/EPS8L1 2 GO:1904424 regulation of GTP binding 2/742 15/18722 0.117239237826864 0.314590893462634 MET/CCPG1 2 GO:1905168 positive regulation of double-strand break repair via homologous recombination 2/742 15/18722 0.117239237826864 0.314590893462634 FUS/PARP1 2 GO:0032943 mononuclear cell proliferation 16/742 291/18722 0.117586688997291 0.31535192380381 CD46/SLC39A10/RPS6/TFRC/MIF/IL6ST/DLG5/CD81/ANXA1/NCSTN/DLG1/CD55/PURA/DOCK8/HES1/IGF2 16 GO:0043433 negative regulation of DNA-binding transcription factor activity 11/742 185/18722 0.118282768403642 0.317046595721102 UFL1/BMP7/TMSB4X/TCF7L2/PURA/DDIT3/EIF2AK4/NFKBIA/ID1/HES1/ANXA4 11 GO:0010821 regulation of mitochondrion organization 9/742 144/18722 0.118882108770106 0.317578195525521 TFRC/HSPA1A/VPS13C/PISD/PMAIP1/NMT1/HUWE1/VDAC1/GPX1 9 GO:0014896 muscle hypertrophy 7/742 104/18722 0.118931105611784 0.317578195525521 IL6ST/ATP2B4/SLC9A1/AKAP13/ROCK1/PARP1/YY1 7 GO:0032963 collagen metabolic process 7/742 104/18722 0.118931105611784 0.317578195525521 CTSL/ITGB1/SERPINH1/MMP15/SUCO/P3H1/CST3 7 GO:0045621 positive regulation of lymphocyte differentiation 7/742 104/18722 0.118931105611784 0.317578195525521 CD46/SOX4/PRKDC/ANXA1/GLI3/GATA3/RHOA 7 GO:0048661 positive regulation of smooth muscle cell proliferation 7/742 104/18722 0.118931105611784 0.317578195525521 JUN/EGFR/GJA1/ADAMTS1/FOXP1/TGM2/HPGD 7 GO:0060419 heart growth 7/742 104/18722 0.118931105611784 0.317578195525521 TGFBR3/GJA1/DUSP6/AKAP13/DUSP9/CITED2/YY1 7 GO:1901890 positive regulation of cell junction assembly 7/742 104/18722 0.118931105611784 0.317578195525521 CAV1/IQGAP1/DLG5/NRP1/ROCK1/TPBG/S100A10 7 GO:0045600 positive regulation of fat cell differentiation 5/742 66/18722 0.120417127295843 0.32137256015206 ZFP36L1/LRP5/BMP7/CDS1/ADIRF 5 GO:0060249 anatomical structure homeostasis 17/742 314/18722 0.120839238573316 0.322200079774812 EGFR/ATP2B1/SLC2A1/ITGB1/GAA/ALDOA/LAMC1/TFRC/GJA1/LSR/ATP6AP1/JAM3/ACTG1/NF1/LTBP3/EPAS1/HSPB1 17 GO:0032092 positive regulation of protein binding 6/742 85/18722 0.120922863947875 0.322200079774812 LRP1/APP/CAV1/NRP1/TCF7L2/RAN 6 GO:0060021 roof of mouth development 6/742 85/18722 0.120922863947875 0.322200079774812 TGFBR3/FRAS1/GLI3/DLG1/ARID5B/TMEM107 6 GO:0031345 negative regulation of cell projection organization 11/742 186/18722 0.121509184417475 0.322598464733242 LRP1/SEMA6A/KANK1/SEMA6D/RTN4/NRP1/TACSTD2/THOC2/ID1/RHOA/CAPZB 11 GO:0120032 regulation of plasma membrane bounded cell projection assembly 11/742 186/18722 0.121509184417475 0.322598464733242 KANK1/CAV1/NRP1/TACSTD2/PFN1/WASF2/PPP1R9A/CLN3/CDC42/EPS8L1/CAPZB 11 GO:0002686 negative regulation of leukocyte migration 4/742 48/18722 0.121594805937914 0.322598464733242 DUSP1/MIF/DPP4/MIA3 4 GO:0042149 cellular response to glucose starvation 4/742 48/18722 0.121594805937914 0.322598464733242 HSPA5/SLC2A1/PMAIP1/HNRNPA1 4 GO:0045839 negative regulation of mitotic nuclear division 4/742 48/18722 0.121594805937914 0.322598464733242 DUSP1/BMP7/TPR/LCMT1 4 GO:0061647 histone H3-K9 modification 4/742 48/18722 0.121594805937914 0.322598464733242 ATRX/ASH1L/RIF1/GATA3 4 GO:1903053 regulation of extracellular matrix organization 4/742 48/18722 0.121594805937914 0.322598464733242 LRP1/DAG1/DPP4/CST3 4 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 4/742 48/18722 0.121594805937914 0.322598464733242 PDIA3/CAV1/PMAIP1/TIMP3 4 GO:0043524 negative regulation of neuron apoptotic process 9/742 145/18722 0.12258670132566 0.324692241808864 LRP1/GRN/NRP1/ISL1/LGMN/RASA1/ERBB3/CLN3/RHOA 9 GO:0001516 prostaglandin biosynthetic process 3/742 31/18722 0.123106997754656 0.324692241808864 MIF/ANXA1/PTGES3 3 GO:0002828 regulation of type 2 immune response 3/742 31/18722 0.123106997754656 0.324692241808864 CD81/ANXA1/GATA3 3 GO:0030149 sphingolipid catabolic process 3/742 31/18722 0.123106997754656 0.324692241808864 HEXA/ASAH1/HEXB 3 GO:0035510 DNA dealkylation 3/742 31/18722 0.123106997754656 0.324692241808864 USP9X/TET2/GATA3 3 GO:0044819 mitotic G1/S transition checkpoint signaling 3/742 31/18722 0.123106997754656 0.324692241808864 SOX4/RPL26/PRKDC 3 GO:0046457 prostanoid biosynthetic process 3/742 31/18722 0.123106997754656 0.324692241808864 MIF/ANXA1/PTGES3 3 GO:0055022 negative regulation of cardiac muscle tissue growth 3/742 31/18722 0.123106997754656 0.324692241808864 GJA1/CITED2/YY1 3 GO:0055075 potassium ion homeostasis 3/742 31/18722 0.123106997754656 0.324692241808864 SLC12A9/ATP1A1/ATP6V1B1 3 GO:0060390 regulation of SMAD protein signal transduction 3/742 31/18722 0.123106997754656 0.324692241808864 LRP1/SPTBN1/PARP1 3 GO:0061117 negative regulation of heart growth 3/742 31/18722 0.123106997754656 0.324692241808864 GJA1/CITED2/YY1 3 GO:0051053 negative regulation of DNA metabolic process 8/742 125/18722 0.123633169290643 0.325732190024415 DUSP1/GJA1/HNRNPA1/RIF1/RAD50/GATA3/PARP1/HNRNPC 8 GO:0070585 protein localization to mitochondrion 8/742 125/18722 0.123633169290643 0.325732190024415 LMAN1/NMT1/DDIT3/CALM1/HUWE1/BCAP31/LEPROT/UBE2L3 8 GO:1901215 negative regulation of neuron death 12/742 208/18722 0.124671704596501 0.328293294619783 LRP1/GRN/SERPINF1/NRP1/ISL1/TMEM259/LGMN/EIF4G1/RASA1/ERBB3/CLN3/RHOA 12 GO:0006493 protein O-linked glycosylation 6/742 86/18722 0.125921740433155 0.331145397432666 GALNT11/B4GAT1/C1GALT1/C1GALT1C1/GXYLT1/TET2 6 GO:1903510 mucopolysaccharide metabolic process 6/742 86/18722 0.125921740433155 0.331145397432666 ITIH5/CHPF/B4GAT1/GNS/GLB1/CLTC 6 GO:0010517 regulation of phospholipase activity 5/742 67/18722 0.126157011734469 0.331145397432666 EGFR/LRP1/FLT1/ANXA1/GNAQ 5 GO:0042490 mechanoreceptor differentiation 5/742 67/18722 0.126157011734469 0.331145397432666 TRIP11/NAGLU/TRIOBP/IFT27/HES1 5 GO:0046635 positive regulation of alpha-beta T cell activation 5/742 67/18722 0.126157011734469 0.331145397432666 CD81/ANXA1/GLI3/CD55/RHOA 5 GO:1903317 regulation of protein maturation 5/742 67/18722 0.126157011734469 0.331145397432666 GLG1/SOX4/TMEM59/ENO1/CLN3 5 GO:0042542 response to hydrogen peroxide 9/742 146/18722 0.126352911204681 0.331483473898633 JUN/LDHA/RHOB/MET/DUSP1/ANXA1/TXN/GPX1/HBA2 9 GO:0030595 leukocyte chemotaxis 13/742 230/18722 0.127002989647126 0.333012085380468 CSF3R/PLEC/BSG/DUSP1/MIF/DPP4/FLT1/JAM3/CALR/ANXA1/LGMN/S100A9/PPIA 13 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 10/742 167/18722 0.127711565350277 0.333628833515401 CDH1/ITGB1/TENM3/DSC3/BSG/CADM1/DSG2/DSC2/FAT1/OBSL1 10 GO:0032874 positive regulation of stress-activated MAPK cascade 8/742 126/18722 0.127737592629562 0.333628833515401 APP/GADD45B/ARL6IP5/EMC10/RB1CC1/GADD45G/CDC42/SDCBP 8 GO:0035821 modulation of process of other organism 7/742 106/18722 0.127863260471172 0.333628833515401 JUN/DAG1/S100A9/STOM/CFL1/EIF2AK4/SERPINB9 7 GO:0071887 leukocyte apoptotic process 7/742 106/18722 0.127863260471172 0.333628833515401 CTSL/SLC39A10/RPS6/ANXA1/GLI3/FOXP1/DOCK8 7 GO:0030308 negative regulation of cell growth 11/742 188/18722 0.128108289228617 0.333628833515401 SEMA6A/SEMA6D/GJA1/RTN4/NRP1/HSPA1A/ENO1/BTG1/HSPA1B/SMARCA2/YY1 11 GO:0060491 regulation of cell projection assembly 11/742 188/18722 0.128108289228617 0.333628833515401 KANK1/CAV1/NRP1/TACSTD2/PFN1/WASF2/PPP1R9A/CLN3/CDC42/EPS8L1/CAPZB 11 GO:0008038 neuron recognition 4/742 49/18722 0.128508192360701 0.333628833515401 APP/BSG/RTN4/NRP1 4 GO:0010823 negative regulation of mitochondrion organization 4/742 49/18722 0.128508192360701 0.333628833515401 TFRC/HSPA1A/HUWE1/GPX1 4 GO:0018198 peptidyl-cysteine modification 4/742 49/18722 0.128508192360701 0.333628833515401 GAPDH/ATP2B4/S100A9/TXN 4 GO:0021515 cell differentiation in spinal cord 4/742 49/18722 0.128508192360701 0.333628833515401 SOX4/LMO4/ISL1/GLI3 4 GO:0030857 negative regulation of epithelial cell differentiation 4/742 49/18722 0.128508192360701 0.333628833515401 CAV1/SRSF6/ID1/HES1 4 GO:0046580 negative regulation of Ras protein signal transduction 4/742 49/18722 0.128508192360701 0.333628833515401 ITGB1/MET/KANK1/RASA1 4 GO:0051932 synaptic transmission, GABAergic 4/742 49/18722 0.128508192360701 0.333628833515401 GABRE/KIF5B/TPBG/CLN3 4 GO:0070169 positive regulation of biomineral tissue development 4/742 49/18722 0.128508192360701 0.333628833515401 FBN2/ATP2B1/BMP7/ATRAID 4 GO:0072666 establishment of protein localization to vacuole 4/742 49/18722 0.128508192360701 0.333628833515401 GCC2/VPS13C/LAMP2/GNPTAB 4 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 4/742 49/18722 0.128508192360701 0.333628833515401 JUN/GJA1/ADAMTS1/HPGD 4 GO:1904894 positive regulation of receptor signaling pathway via STAT 4/742 49/18722 0.128508192360701 0.333628833515401 CSH1/PRLR/IL10RB/HES1 4 GO:0060041 retina development in camera-type eye 9/742 147/18722 0.130180224029715 0.333628833515401 ATP2B1/SERPINF1/RPL24/LRP5/NAGLU/NRP1/ATP2B4/MAN2A1/OBSL1 9 GO:0001845 phagolysosome assembly 2/742 16/18722 0.130615012959268 0.333628833515401 SYT7/CLN3 2 GO:0001977 renal system process involved in regulation of blood volume 2/742 16/18722 0.130615012959268 0.333628833515401 GJA1/GJA5 2 GO:0002713 negative regulation of B cell mediated immunity 2/742 16/18722 0.130615012959268 0.333628833515401 CD46/CD55 2 GO:0002830 positive regulation of type 2 immune response 2/742 16/18722 0.130615012959268 0.333628833515401 CD81/GATA3 2 GO:0002890 negative regulation of immunoglobulin mediated immune response 2/742 16/18722 0.130615012959268 0.333628833515401 CD46/CD55 2 GO:0002921 negative regulation of humoral immune response 2/742 16/18722 0.130615012959268 0.333628833515401 CD46/CD55 2 GO:0003084 positive regulation of systemic arterial blood pressure 2/742 16/18722 0.130615012959268 0.333628833515401 NR2F2/RHOA 2 GO:0006004 fucose metabolic process 2/742 16/18722 0.130615012959268 0.333628833515401 FUCA1/FUT8 2 GO:0007635 chemosensory behavior 2/742 16/18722 0.130615012959268 0.333628833515401 TPBG/ATP6V1B1 2 GO:0021535 cell migration in hindbrain 2/742 16/18722 0.130615012959268 0.333628833515401 ITGB1/RERE 2 GO:0032274 gonadotropin secretion 2/742 16/18722 0.130615012959268 0.333628833515401 GJA1/CGA 2 GO:0034138 toll-like receptor 3 signaling pathway 2/742 16/18722 0.130615012959268 0.333628833515401 CAV1/COLEC12 2 GO:0048557 embryonic digestive tract morphogenesis 2/742 16/18722 0.130615012959268 0.333628833515401 GLI3/NIPBL 2 GO:0050862 positive regulation of T cell receptor signaling pathway 2/742 16/18722 0.130615012959268 0.333628833515401 KCNN4/CD81 2 GO:0050884 neuromuscular process controlling posture 2/742 16/18722 0.130615012959268 0.333628833515401 GAA/TMEM150C 2 GO:0051014 actin filament severing 2/742 16/18722 0.130615012959268 0.333628833515401 CFL1/DSTN 2 GO:0051238 sequestering of metal ion 2/742 16/18722 0.130615012959268 0.333628833515401 FTH1/S100A9 2 GO:0061548 ganglion development 2/742 16/18722 0.130615012959268 0.333628833515401 NRP2/NRP1 2 GO:0070365 hepatocyte differentiation 2/742 16/18722 0.130615012959268 0.333628833515401 ANXA1/KRT18 2 GO:0072109 glomerular mesangium development 2/742 16/18722 0.130615012959268 0.333628833515401 EGR1/BMP7 2 GO:0072148 epithelial cell fate commitment 2/742 16/18722 0.130615012959268 0.333628833515401 NRP1/NR2F2 2 GO:0097202 activation of cysteine-type endopeptidase activity 2/742 16/18722 0.130615012959268 0.333628833515401 ASPH/LGMN 2 GO:0097284 hepatocyte apoptotic process 2/742 16/18722 0.130615012959268 0.333628833515401 KRT8/KRT18 2 GO:0098969 neurotransmitter receptor transport to postsynaptic membrane 2/742 16/18722 0.130615012959268 0.333628833515401 VAMP2/RAB11A 2 GO:0099633 protein localization to postsynaptic specialization membrane 2/742 16/18722 0.130615012959268 0.333628833515401 DAG1/DLG1 2 GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane 2/742 16/18722 0.130615012959268 0.333628833515401 DAG1/DLG1 2 GO:1901163 regulation of trophoblast cell migration 2/742 16/18722 0.130615012959268 0.333628833515401 GJA1/CALR 2 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2/742 16/18722 0.130615012959268 0.333628833515401 MIF/RPL26 2 GO:1902570 protein localization to nucleolus 2/742 16/18722 0.130615012959268 0.333628833515401 NPM1/RAN 2 GO:2000765 regulation of cytoplasmic translation 2/742 16/18722 0.130615012959268 0.333628833515401 DHX36/PKM 2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining 2/742 16/18722 0.130615012959268 0.333628833515401 PRKDC/RIF1 2 GO:2001224 positive regulation of neuron migration 2/742 16/18722 0.130615012959268 0.333628833515401 SEMA6A/NIPBL 2 GO:0015980 energy derivation by oxidation of organic compounds 17/742 318/18722 0.130912442045491 0.334143895420035 GAA/COX6A1/PLEC/IL6ST/AGL/IL10RB/ACADVL/RB1CC1/NDUFB9/UQCRH/PTGES3/COX8C/RHOA/IGF2/PYGL/UGP2/COX5A 17 GO:0002685 regulation of leukocyte migration 12/742 210/18722 0.130992811065674 0.334143895420035 APP/DUSP1/MIF/DPP4/JAM3/CALR/MIA3/CD81/ANXA1/LGMN/DOCK8/RHOA 12 GO:1903578 regulation of ATP metabolic process 6/742 87/18722 0.131019580046277 0.334143895420035 APP/TMSB4X/ENO1/NCOR1/PARP1/RHOA 6 GO:0007585 respiratory gaseous exchange by respiratory system 5/742 68/18722 0.132020170858478 0.334223189761264 GAA/MAN2A1/MAN1A2/SLC5A3/FUT8 5 GO:0009206 purine ribonucleoside triphosphate biosynthetic process 5/742 68/18722 0.132020170858478 0.334223189761264 ALDOA/TMSB4X/ENO1/NME3/PARP1 5 GO:0042267 natural killer cell mediated cytotoxicity 5/742 68/18722 0.132020170858478 0.334223189761264 CADM1/KIF5B/LAMP1/SERPINB9/TUBB4B 5 GO:0042698 ovulation cycle 5/742 68/18722 0.132020170858478 0.334223189761264 EGFR/HSPA5/SERPINF1/ADAMTS1/EGR1 5 GO:0042987 amyloid precursor protein catabolic process 5/742 68/18722 0.132020170858478 0.334223189761264 DHCR24/RTN4/NCSTN/ROCK1/CLN3 5 GO:0003338 metanephros morphogenesis 3/742 32/18722 0.132065519517002 0.334223189761264 LGR4/FRAS1/HES1 3 GO:0009954 proximal/distal pattern formation 3/742 32/18722 0.132065519517002 0.334223189761264 PBX1/GLI3/IRX2 3 GO:0048841 regulation of axon extension involved in axon guidance 3/742 32/18722 0.132065519517002 0.334223189761264 SEMA6A/SEMA6D/NRP1 3 GO:0060317 cardiac epithelial to mesenchymal transition 3/742 32/18722 0.132065519517002 0.334223189761264 TGFBR3/RTN4/PDCD4 3 GO:0071875 adrenergic receptor signaling pathway 3/742 32/18722 0.132065519517002 0.334223189761264 ATP2B4/ADRB1/AKAP13 3 GO:0097345 mitochondrial outer membrane permeabilization 3/742 32/18722 0.132065519517002 0.334223189761264 HSPA1A/NMT1/VDAC2 3 GO:1900745 positive regulation of p38MAPK cascade 3/742 32/18722 0.132065519517002 0.334223189761264 GADD45B/EMC10/GADD45G 3 GO:1901185 negative regulation of ERBB signaling pathway 3/742 32/18722 0.132065519517002 0.334223189761264 EGFR/LGMN/PTPN12 3 GO:1903955 positive regulation of protein targeting to mitochondrion 3/742 32/18722 0.132065519517002 0.334223189761264 HUWE1/LEPROT/UBE2L3 3 GO:1905476 negative regulation of protein localization to membrane 3/742 32/18722 0.132065519517002 0.334223189761264 TMEM59/HECTD1/CLTC 3 GO:0021761 limbic system development 7/742 107/18722 0.132452588435576 0.334859665748079 NRP2/NRP1/ATP2B4/CDK6/GLI3/KIF5B/ANXA3 7 GO:0031532 actin cytoskeleton reorganization 7/742 107/18722 0.132452588435576 0.334859665748079 IQGAP2/PLEC/NRP1/ANXA1/CDC42/RHOA/PHPT1 7 GO:0042180 cellular ketone metabolic process 12/742 211/18722 0.134218710766078 0.338977725554411 CAV1/EGR1/ATP2B4/TPI1/ANXA1/NMT1/NCOR1/ACADVL/ADM/CLN3/CYP11A1/HSD17B1 12 GO:0050807 regulation of synapse organization 12/742 211/18722 0.134218710766078 0.338977725554411 NRP2/APP/DAG1/DLG5/EIF4G1/PPP1R9A/TPBG/CFL1/DHX36/CLN3/CDC42/RHOA 12 GO:0007632 visual behavior 4/742 50/18722 0.135581399303463 0.341198223412688 APP/ITGB1/NF1/DYNLRB1 4 GO:0018023 peptidyl-lysine trimethylation 4/742 50/18722 0.135581399303463 0.341198223412688 ATRX/BRD4/TET2/RTF1 4 GO:0043268 positive regulation of potassium ion transport 4/742 50/18722 0.135581399303463 0.341198223412688 AKAP9/KCNN4/KIF5B/DLG1 4 GO:0045058 T cell selection 4/742 50/18722 0.135581399303463 0.341198223412688 CTSL/GLI3/GATA3/RHOA 4 GO:0060425 lung morphogenesis 4/742 50/18722 0.135581399303463 0.341198223412688 DAG1/DLG5/SRSF6/CDC42 4 GO:0071709 membrane assembly 4/742 50/18722 0.135581399303463 0.341198223412688 CAV1/ANK3/SPTBN1/S100A10 4 GO:0110151 positive regulation of biomineralization 4/742 50/18722 0.135581399303463 0.341198223412688 FBN2/ATP2B1/BMP7/ATRAID 4 GO:0007004 telomere maintenance via telomerase 5/742 69/18722 0.138003652197676 0.346940479316295 HNRNPA1/RAD50/HNRNPC/PTGES3/CCT3 5 GO:0009145 purine nucleoside triphosphate biosynthetic process 5/742 69/18722 0.138003652197676 0.346940479316295 ALDOA/TMSB4X/ENO1/NME3/PARP1 5 GO:0007498 mesoderm development 8/742 129/18722 0.140467090651978 0.352412937302749 ITGB4/ITGB1/WLS/GJA1/ZFP36L1/BMP7/CITED2/MEST 8 GO:0031349 positive regulation of defense response 15/742 278/18722 0.141172329601052 0.352412937302749 EGFR/NEAT1/GRN/APP/CTSC/CADM1/IL6ST/GJA1/PRKDC/CD81/S100A9/LAMP1/NFKBIA/TGM2/PDCD4 15 GO:0010165 response to X-ray 3/742 33/18722 0.141243442778973 0.352412937302749 ANXA1/NIPBL/GATA3 3 GO:0036336 dendritic cell migration 3/742 33/18722 0.141243442778973 0.352412937302749 CALR/DOCK8/CDC42 3 GO:0042558 pteridine-containing compound metabolic process 3/742 33/18722 0.141243442778973 0.352412937302749 SLC19A1/FOLR1/MTR 3 GO:0045648 positive regulation of erythrocyte differentiation 3/742 33/18722 0.141243442778973 0.352412937302749 PRKDC/HSPA1A/HSPA1B 3 GO:0048333 mesodermal cell differentiation 3/742 33/18722 0.141243442778973 0.352412937302749 ITGB4/ITGB1/GJA1 3 GO:0070570 regulation of neuron projection regeneration 3/742 33/18722 0.141243442778973 0.352412937302749 LRP1/GRN/PTPRF 3 GO:0071539 protein localization to centrosome 3/742 33/18722 0.141243442778973 0.352412937302749 GOLGB1/CEP350/PCM1 3 GO:0120033 negative regulation of plasma membrane bounded cell projection assembly 3/742 33/18722 0.141243442778973 0.352412937302749 KANK1/TACSTD2/CAPZB 3 GO:1900181 negative regulation of protein localization to nucleus 3/742 33/18722 0.141243442778973 0.352412937302749 FERMT1/MAGED1/TRIM29 3 GO:0046330 positive regulation of JNK cascade 6/742 89/18722 0.141505110528893 0.352412937302749 APP/GADD45B/RB1CC1/GADD45G/CDC42/SDCBP 6 GO:0051781 positive regulation of cell division 6/742 89/18722 0.141505110528893 0.352412937302749 PKN2/YBX1/CDC42/RHOA/IGF2/LBH 6 GO:0006821 chloride transport 7/742 109/18722 0.141872025945014 0.352412937302749 SLC26A2/CLDN4/SLC12A9/GABRE/CLIC3/PCYOX1/FXYD3 7 GO:0032410 negative regulation of transporter activity 7/742 109/18722 0.141872025945014 0.352412937302749 CAV1/ANK3/C4orf3/GSTO1/CALM1/CALM2/YWHAE 7 GO:0042129 regulation of T cell proliferation 10/742 171/18722 0.142372167437482 0.352412937302749 CD46/TFRC/IL6ST/DLG5/CD81/ANXA1/DLG1/CD55/HES1/IGF2 10 GO:2000116 regulation of cysteine-type endopeptidase activity 13/742 235/18722 0.142460257522814 0.352412937302749 CTSD/DHCR24/POR/ARL6IP5/ASPH/LGMN/S100A9/PMAIP1/GPX1/SIAH2/BCAP31/SERPINB9/RHOA 13 GO:0006636 unsaturated fatty acid biosynthetic process 4/742 51/18722 0.142808678590203 0.352412937302749 MIF/DEGS1/ANXA1/PTGES3 4 GO:0014009 glial cell proliferation 4/742 51/18722 0.142808678590203 0.352412937302749 EGFR/UFL1/SOX4/HES1 4 GO:0045661 regulation of myoblast differentiation 4/742 51/18722 0.142808678590203 0.352412937302749 ZFP36L1/BTG1/DDIT3/MBNL3 4 GO:0065002 intracellular protein transmembrane transport 4/742 51/18722 0.142808678590203 0.352412937302749 HSPA5/SEC62/SEC61A1/SEC63 4 GO:0009615 response to virus 19/742 367/18722 0.143210496005661 0.352412937302749 TPT1/IL10RB/CDK6/ENO1/TRIM44/PMAIP1/PUM1/DDX17/SERINC3/CFL1/DHX36/EIF2AK4/PCBP2/GATA3/HSPB1/ADAR/HMGA1/EIF5A/BANF1 19 GO:1903706 regulation of hemopoiesis 19/742 367/18722 0.143210496005661 0.352412937302749 JUN/FBN1/FOS/CSF3R/CD46/SOX4/PRKDC/ZFP36L1/ATP6AP1/ESRRA/HSPA1A/ANXA1/CDK6/GLI3/HSPA1B/FOXP1/NFKBIA/GATA3/RHOA 19 GO:0002263 cell activation involved in immune response 15/742 279/18722 0.144093310631214 0.352412937302749 CD46/LRP1/GRN/APP/RPS6/TFRC/CD81/ANXA1/VAMP2/FOXP1/LAMP1/RIF1/EIF2AK4/GATA3/ANXA3 15 GO:1902105 regulation of leukocyte differentiation 15/742 279/18722 0.144093310631214 0.352412937302749 JUN/FBN1/FOS/CD46/SOX4/PRKDC/ZFP36L1/ATP6AP1/ESRRA/ANXA1/CDK6/GLI3/FOXP1/GATA3/RHOA 15 GO:0070830 bicellular tight junction assembly 5/742 70/18722 0.144104385480788 0.352412937302749 CLDN4/GJA1/DLG1/ROCK1/MARVELD3 5 GO:0044242 cellular lipid catabolic process 12/742 214/18722 0.144154506434839 0.352412937302749 LRP1/HEXA/SLC27A2/FUCA1/CROT/ACADVL/ASAH1/HADHA/PLBD1/PRDX6/HEXB/ETFA 12 GO:0001780 neutrophil homeostasis 2/742 17/18722 0.144318091531065 0.352412937302749 JAM3/ANXA1 2 GO:0001829 trophectodermal cell differentiation 2/742 17/18722 0.144318091531065 0.352412937302749 JUNB/CITED2 2 GO:0006577 amino-acid betaine metabolic process 2/742 17/18722 0.144318091531065 0.352412937302749 POR/CROT 2 GO:0010566 regulation of ketone biosynthetic process 2/742 17/18722 0.144318091531065 0.352412937302749 EGR1/ADM 2 GO:0021924 cell proliferation in external granule layer 2/742 17/18722 0.144318091531065 0.352412937302749 SLC6A4/RERE 2 GO:0021930 cerebellar granule cell precursor proliferation 2/742 17/18722 0.144318091531065 0.352412937302749 SLC6A4/RERE 2 GO:0031445 regulation of heterochromatin assembly 2/742 17/18722 0.144318091531065 0.352412937302749 MPHOSPH8/TPR 2 GO:0033151 V(D)J recombination 2/742 17/18722 0.144318091531065 0.352412937302749 PRKDC/YY1 2 GO:0033623 regulation of integrin activation 2/742 17/18722 0.144318091531065 0.352412937302749 JAM3/FERMT1 2 GO:0035518 histone H2A monoubiquitination 2/742 17/18722 0.144318091531065 0.352412937302749 DDB1/SKP1 2 GO:0035729 cellular response to hepatocyte growth factor stimulus 2/742 17/18722 0.144318091531065 0.352412937302749 NRP1/LGMN 2 GO:0042448 progesterone metabolic process 2/742 17/18722 0.144318091531065 0.352412937302749 EGR1/ADM 2 GO:0042953 lipoprotein transport 2/742 17/18722 0.144318091531065 0.352412937302749 LRP1/MIA3 2 GO:0044539 long-chain fatty acid import into cell 2/742 17/18722 0.144318091531065 0.352412937302749 SLC2A1/SLC27A2 2 GO:0045815 positive regulation of gene expression, epigenetic 2/742 17/18722 0.144318091531065 0.352412937302749 SERTAD1/ARID1A 2 GO:0055064 chloride ion homeostasis 2/742 17/18722 0.144318091531065 0.352412937302749 SLC12A9/ATP6V1B1 2 GO:0055083 monovalent inorganic anion homeostasis 2/742 17/18722 0.144318091531065 0.352412937302749 SLC12A9/ATP6V1B1 2 GO:0060033 anatomical structure regression 2/742 17/18722 0.144318091531065 0.352412937302749 FLT1/LRP5 2 GO:0061158 3'-UTR-mediated mRNA destabilization 2/742 17/18722 0.144318091531065 0.352412937302749 ZFP36L1/DHX36 2 GO:0061298 retina vasculature development in camera-type eye 2/742 17/18722 0.144318091531065 0.352412937302749 LRP5/NRP1 2 GO:0070206 protein trimerization 2/742 17/18722 0.144318091531065 0.352412937302749 MIF/SLC1A5 2 GO:0070293 renal absorption 2/742 17/18722 0.144318091531065 0.352412937302749 CLDN4/MAGED2 2 GO:0071816 tail-anchored membrane protein insertion into ER membrane 2/742 17/18722 0.144318091531065 0.352412937302749 EMC1/EMC10 2 GO:0072673 lamellipodium morphogenesis 2/742 17/18722 0.144318091531065 0.352412937302749 KANK1/WASF2 2 GO:0090136 epithelial cell-cell adhesion 2/742 17/18722 0.144318091531065 0.352412937302749 DSP/ITGB5 2 GO:0090713 immunological memory process 2/742 17/18722 0.144318091531065 0.352412937302749 CD46/CD81 2 GO:0120261 regulation of heterochromatin organization 2/742 17/18722 0.144318091531065 0.352412937302749 MPHOSPH8/TPR 2 GO:0140354 lipid import into cell 2/742 17/18722 0.144318091531065 0.352412937302749 SLC2A1/SLC27A2 2 GO:1902358 sulfate transmembrane transport 2/742 17/18722 0.144318091531065 0.352412937302749 SLC26A2/SLC13A4 2 GO:1903540 establishment of protein localization to postsynaptic membrane 2/742 17/18722 0.144318091531065 0.352412937302749 VAMP2/RAB11A 2 GO:2000811 negative regulation of anoikis 2/742 17/18722 0.144318091531065 0.352412937302749 ITGB1/CAV1 2 GO:0006631 fatty acid metabolic process 20/742 390/18722 0.144924162037877 0.353718063471894 ACSS1/CAV1/MIF/SLC27A2/HACD3/POR/DEGS1/ANXA1/CROT/NCOR1/ACADVL/ASAH1/ATP6V1B1/HADHA/GPX1/PTGES3/CYP2J2/GPX4/HPGD/ETFA 20 GO:0001935 endothelial cell proliferation 11/742 193/18722 0.14544476576753 0.354813403897086 NRP2/CAV1/GJA1/FLT1/NRP1/NR2F2/NF1/MYDGF/DLG1/EMC10/IGF2 11 GO:0055067 monovalent inorganic cation homeostasis 9/742 151/18722 0.146088967188552 0.356209031545629 GRN/SLC12A9/ATP6AP1/SLC9A1/ATP6AP2/ATP1A1/TMEM165/ATP6V1B1/CLN3 9 GO:0001678 cellular glucose homeostasis 10/742 172/18722 0.146168700257222 0.356227616808425 LRP1/SERPINF1/SOX4/DYNLL1/LRP5/IGF1R/KIF5B/TRA2B/HMGN3/PHPT1 10 GO:0042593 glucose homeostasis 14/742 258/18722 0.146592545058178 0.357084404628894 LRP1/RPS6/SERPINF1/SOX4/DYNLL1/LRP5/IGF1R/KIF5B/TRA2B/TCF7L2/SLC16A1/HMGN3/PHPT1/PYGL 14 GO:0009408 response to heat 7/742 110/18722 0.146699666196957 0.357169221790522 TPR/HSPA1A/HSPA1B/SLC52A3/DHX36/DNAJB1/YWHAE 7 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 6/742 90/18722 0.146889074016279 0.357454199822866 CAV1/HSPA1A/HSPA1B/HECTD1/BCAP31/DDA1 6 GO:0033500 carbohydrate homeostasis 14/742 259/18722 0.149704070869823 0.364125115754272 LRP1/RPS6/SERPINF1/SOX4/DYNLL1/LRP5/IGF1R/KIF5B/TRA2B/TCF7L2/SLC16A1/HMGN3/PHPT1/PYGL 14 GO:0010718 positive regulation of epithelial to mesenchymal transition 4/742 52/18722 0.150184139166213 0.364396760973585 BMP7/ISL1/TCF7L2/SDCBP 4 GO:0043277 apoptotic cell clearance 4/742 52/18722 0.150184139166213 0.364396760973585 LRP1/ITGAV/ANXA1/TGM2 4 GO:0051496 positive regulation of stress fiber assembly 4/742 52/18722 0.150184139166213 0.364396760973585 NRP1/S100A10/CDC42/RHOA 4 GO:0051092 positive regulation of NF-kappaB transcription factor activity 9/742 152/18722 0.150212838564927 0.364396760973585 APP/TFRC/CAV1/NPM1/HSPA1A/S100A9/HSPA1B/ERC1/PPIA 9 GO:0002228 natural killer cell mediated immunity 5/742 71/18722 0.150319191085912 0.364396760973585 CADM1/KIF5B/LAMP1/SERPINB9/TUBB4B 5 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 3/742 34/18722 0.150627163139284 0.364396760973585 GSTO1/CALM1/CALM2 3 GO:0035909 aorta morphogenesis 3/742 34/18722 0.150627163139284 0.364396760973585 LRP1/SOX4/HES1 3 GO:0048261 negative regulation of receptor-mediated endocytosis 3/742 34/18722 0.150627163139284 0.364396760973585 ITGAV/LRPAP1/SDCBP 3 GO:0048536 spleen development 3/742 34/18722 0.150627163139284 0.364396760973585 PBX1/PRKDC/CITED2 3 GO:0055094 response to lipoprotein particle 3/742 34/18722 0.150627163139284 0.364396760973585 ITGB1/MIA3/CD81 3 GO:0070884 regulation of calcineurin-NFAT signaling cascade 3/742 34/18722 0.150627163139284 0.364396760973585 ATP2B4/NFAT5/SLC9A1 3 GO:0090288 negative regulation of cellular response to growth factor stimulus 7/742 111/18722 0.151604178652858 0.366580833355418 LRP2/FBN1/SEMA6A/CRIM1/ATP2B4/GPC1/GATA3 7 GO:0045582 positive regulation of T cell differentiation 6/742 91/18722 0.152364553868351 0.368239185963626 CD46/SOX4/ANXA1/GLI3/GATA3/RHOA 6 GO:0051091 positive regulation of DNA-binding transcription factor activity 14/742 260/18722 0.152850855266965 0.369233850864943 APP/TFRC/CAV1/PLPP3/LRP5/NPM1/HSPA1A/S100A9/HSPA1B/ERC1/PPIA/DDIT3/ARID5B/ANXA3 14 GO:0048639 positive regulation of developmental growth 10/742 174/18722 0.153915826076162 0.37162472180657 LRP1/GOLGA4/MACF1/TGFBR3/PRKDC/NRP1/NIPBL/CELF1/IGF2/RAB11A 10 GO:0007338 single fertilization 9/742 153/18722 0.154393992101299 0.372597127982617 CD46/ALDOA/SPESP1/FOLR1/ASH1L/KDM5B/HEXB/VDAC2/CCT3 9 GO:0016311 dephosphorylation 21/742 417/18722 0.15623675056356 0.373634682023728 HSP90B1/SLC39A10/BOD1L1/DUSP1/DUSP6/PLPP3/PPP1R15A/PTPRF/DLG1/PTPRA/PTPN12/ROCK1/ATP1A1/CTDSPL/PPIA/PTPN14/CALM1/PHPT1/CALM2/CSNK2B/YWHAE 21 GO:0006006 glucose metabolic process 11/742 196/18722 0.156406865449661 0.373634682023728 GAPDH/GAA/LRP5/TPI1/ENO1/DDB1/PMAIP1/RANBP2/SLC35B4/IGF2/LCMT1 11 GO:0000956 nuclear-transcribed mRNA catabolic process 7/742 112/18722 0.156584188005979 0.373634682023728 ZFP36L1/TNRC6A/UPF2/TNRC6B/DHX36/DDX5/SSB 7 GO:0002821 positive regulation of adaptive immune response 7/742 112/18722 0.156584188005979 0.373634682023728 TFRC/IL6ST/CD81/CD55/RIF1/EIF2AK4/GATA3 7 GO:0009141 nucleoside triphosphate metabolic process 7/742 112/18722 0.156584188005979 0.373634682023728 ALDOA/TMSB4X/ENO1/NME3/PARP1/RAN/RHOA 7 GO:0010633 negative regulation of epithelial cell migration 7/742 112/18722 0.156584188005979 0.373634682023728 SERPINF1/TACSTD2/ATP2B4/NR2F2/MARVELD3/RHOA/CSNK2B 7 GO:0000271 polysaccharide biosynthetic process 5/742 72/18722 0.156644788417193 0.373634682023728 AGL/CLTC/PTGES3/IGF2/UGP2 5 GO:0001707 mesoderm formation 5/742 72/18722 0.156644788417193 0.373634682023728 ITGB4/ITGB1/WLS/GJA1/BMP7 5 GO:0051057 positive regulation of small GTPase mediated signal transduction 5/742 72/18722 0.156644788417193 0.373634682023728 ADGRG1/ITGAV/AKAP13/TGM2/DYNLT1 5 GO:0070227 lymphocyte apoptotic process 5/742 72/18722 0.156644788417193 0.373634682023728 SLC39A10/RPS6/GLI3/FOXP1/DOCK8 5 GO:0031279 regulation of cyclase activity 4/742 53/18722 0.157701766999307 0.373634682023728 AKAP9/NF1/CALM1/CALM2 4 GO:0045806 negative regulation of endocytosis 4/742 53/18722 0.157701766999307 0.373634682023728 ITGAV/LRPAP1/CAV1/SDCBP 4 GO:0071320 cellular response to cAMP 4/742 53/18722 0.157701766999307 0.373634682023728 AKAP9/HSPA5/APP/ZFP36L1 4 GO:0032465 regulation of cytokinesis 6/742 92/18722 0.15792949613618 0.373634682023728 PKN2/CALM1/CDC42/RHOA/RAB11A/CALM2 6 GO:0050803 regulation of synapse structure or activity 12/742 218/18722 0.157992551686509 0.373634682023728 NRP2/APP/DAG1/DLG5/EIF4G1/PPP1R9A/TPBG/CFL1/DHX36/CLN3/CDC42/RHOA 12 GO:0002076 osteoblast development 2/742 18/18722 0.158301614356578 0.373634682023728 JUND/LRP5 2 GO:0002544 chronic inflammatory response 2/742 18/18722 0.158301614356578 0.373634682023728 GJA1/S100A9 2 GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 2/742 18/18722 0.158301614356578 0.373634682023728 CD46/CD55 2 GO:0003128 heart field specification 2/742 18/18722 0.158301614356578 0.373634682023728 LRP2/ISL1 2 GO:0006337 nucleosome disassembly 2/742 18/18722 0.158301614356578 0.373634682023728 ARID1A/HMGA1 2 GO:0008272 sulfate transport 2/742 18/18722 0.158301614356578 0.373634682023728 SLC26A2/SLC13A4 2 GO:0021534 cell proliferation in hindbrain 2/742 18/18722 0.158301614356578 0.373634682023728 SLC6A4/RERE 2 GO:0030728 ovulation 2/742 18/18722 0.158301614356578 0.373634682023728 ADAMTS1/HPGD 2 GO:0032769 negative regulation of monooxygenase activity 2/742 18/18722 0.158301614356578 0.373634682023728 CAV1/ATP2B4 2 GO:0035743 CD4-positive, alpha-beta T cell cytokine production 2/742 18/18722 0.158301614356578 0.373634682023728 CD81/GATA3 2 GO:0043217 myelin maintenance 2/742 18/18722 0.158301614356578 0.373634682023728 PLEC/DEGS1 2 GO:0044872 lipoprotein localization 2/742 18/18722 0.158301614356578 0.373634682023728 LRP1/MIA3 2 GO:0048268 clathrin coat assembly 2/742 18/18722 0.158301614356578 0.373634682023728 CLTC/CLTA 2 GO:0060008 Sertoli cell differentiation 2/742 18/18722 0.158301614356578 0.373634682023728 ATRX/CTSV 2 GO:0060192 negative regulation of lipase activity 2/742 18/18722 0.158301614356578 0.373634682023728 POR/ANXA1 2 GO:0060716 labyrinthine layer blood vessel development 2/742 18/18722 0.158301614356578 0.373634682023728 JUNB/HES1 2 GO:0060973 cell migration involved in heart development 2/742 18/18722 0.158301614356578 0.373634682023728 BMP7/FOLR1 2 GO:0071360 cellular response to exogenous dsRNA 2/742 18/18722 0.158301614356578 0.373634682023728 CAV1/COLEC12 2 GO:0072079 nephron tubule formation 2/742 18/18722 0.158301614356578 0.373634682023728 IRX2/GATA3 2 GO:0072234 metanephric nephron tubule development 2/742 18/18722 0.158301614356578 0.373634682023728 LGR4/HES1 2 GO:0080182 histone H3-K4 trimethylation 2/742 18/18722 0.158301614356578 0.373634682023728 TET2/RTF1 2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis 2/742 18/18722 0.158301614356578 0.373634682023728 LGR4/MAGED1 2 GO:0097094 craniofacial suture morphogenesis 2/742 18/18722 0.158301614356578 0.373634682023728 GLI3/TMEM107 2 GO:0098877 neurotransmitter receptor transport to plasma membrane 2/742 18/18722 0.158301614356578 0.373634682023728 VAMP2/RAB11A 2 GO:1900006 positive regulation of dendrite development 2/742 18/18722 0.158301614356578 0.373634682023728 IQGAP1/BMP7 2 GO:1900242 regulation of synaptic vesicle endocytosis 2/742 18/18722 0.158301614356578 0.373634682023728 ROCK1/CALM1 2 GO:1900424 regulation of defense response to bacterium 2/742 18/18722 0.158301614356578 0.373634682023728 GRN/FOXP1 2 GO:1902074 response to salt 2/742 18/18722 0.158301614356578 0.373634682023728 HSPA5/HNRNPA1 2 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus 2/742 18/18722 0.158301614356578 0.373634682023728 SEMA6A/ATP2B4 2 GO:2000136 regulation of cell proliferation involved in heart morphogenesis 2/742 18/18722 0.158301614356578 0.373634682023728 ISL1/HES1 2 GO:0010565 regulation of cellular ketone metabolic process 8/742 133/18722 0.158378749829491 0.373634682023728 CAV1/EGR1/ATP2B4/ANXA1/NCOR1/ACADVL/ADM/CLN3 8 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 8/742 133/18722 0.158378749829491 0.373634682023728 CTSC/CAV1/TMEM259/HSPA1A/HSPA1B/HECTD1/BCAP31/DDA1 8 GO:0007020 microtubule nucleation 3/742 35/18722 0.160203103397412 0.376142267482517 AKAP9/HSPA1A/HSPA1B 3 GO:0015695 organic cation transport 3/742 35/18722 0.160203103397412 0.376142267482517 SLC38A2/SLC44A2/SLC19A3 3 GO:0018149 peptide cross-linking 3/742 35/18722 0.160203103397412 0.376142267482517 DSP/ANXA1/TGM2 3 GO:0034331 cell junction maintenance 3/742 35/18722 0.160203103397412 0.376142267482517 DLG1/ERC1/SDF4 3 GO:0043243 positive regulation of protein-containing complex disassembly 3/742 35/18722 0.160203103397412 0.376142267482517 IGF1R/DSTN/EIF5A 3 GO:0090181 regulation of cholesterol metabolic process 3/742 35/18722 0.160203103397412 0.376142267482517 POR/MBTPS1/ACADVL 3 GO:0106056 regulation of calcineurin-mediated signaling 3/742 35/18722 0.160203103397412 0.376142267482517 ATP2B4/NFAT5/SLC9A1 3 GO:1903514 release of sequestered calcium ion into cytosol by endoplasmic reticulum 3/742 35/18722 0.160203103397412 0.376142267482517 GSTO1/CALM1/CALM2 3 GO:1905508 protein localization to microtubule organizing center 3/742 35/18722 0.160203103397412 0.376142267482517 GOLGB1/CEP350/PCM1 3 GO:2000403 positive regulation of lymphocyte migration 3/742 35/18722 0.160203103397412 0.376142267482517 APP/DOCK8/RHOA 3 GO:0050863 regulation of T cell activation 17/742 329/18722 0.161020909917544 0.377882800471576 CD46/TFRC/CAV1/SOX4/IL6ST/DPP4/DLG5/CD81/ANXA1/GLI3/DLG1/CD55/GATA3/DOCK8/HES1/RHOA/IGF2 17 GO:0034764 positive regulation of transmembrane transport 12/742 219/18722 0.161555088565463 0.378956380585655 AKAP9/TCAF1/ITGB1/KCNN4/ANK3/GSTO1/TMSB4X/SLC9A1/KIF5B/ACTN4/CALM1/CALM2 12 GO:0002708 positive regulation of lymphocyte mediated immunity 7/742 113/18722 0.161638266623149 0.378971541109804 CADM1/TFRC/CD81/CD55/LAMP1/RIF1/GATA3 7 GO:0048562 embryonic organ morphogenesis 15/742 285/18722 0.162306913517593 0.380358706250906 FBN2/FBN1/EFEMP1/NAGLU/BMP7/FOLR1/GLI3/DLG1/NIPBL/TRIOBP/SLC39A1/ATP6V1B1/CITED2/GATA3/HES1 15 GO:0034614 cellular response to reactive oxygen species 9/742 155/18722 0.162925104918106 0.381260933594551 JUN/EGFR/FOS/RHOB/MET/SOD3/BMP7/ANXA1/TXN 9 GO:0002705 positive regulation of leukocyte mediated immunity 8/742 134/18722 0.163017949372262 0.381260933594551 CADM1/TFRC/CD81/CD55/LAMP1/DHX36/RIF1/GATA3 8 GO:0045739 positive regulation of DNA repair 5/742 73/18722 0.163077804187305 0.381260933594551 EGFR/FUS/PRKDC/RIF1/PARP1 5 GO:0050848 regulation of calcium-mediated signaling 5/742 73/18722 0.163077804187305 0.381260933594551 ATP2B4/NFAT5/SLC9A1/CALM1/CALM2 5 GO:0061035 regulation of cartilage development 5/742 73/18722 0.163077804187305 0.381260933594551 EFEMP1/GLG1/POR/GLI3/LTBP3 5 GO:0032088 negative regulation of NF-kappaB transcription factor activity 6/742 93/18722 0.163581778068381 0.382077533644352 UFL1/BMP7/TMSB4X/DDIT3/NFKBIA/ANXA4 6 GO:1902807 negative regulation of cell cycle G1/S phase transition 6/742 93/18722 0.163581778068381 0.382077533644352 SOX4/RPL26/PRKDC/DLG1/CTDSPL/BRD7 6 GO:0070371 ERK1 and ERK2 cascade 17/742 330/18722 0.16392872221754 0.382554987159234 EGFR/FBLN1/LRP1/ITGAV/APP/SEMA6A/EIF3A/DUSP1/MIF/DUSP6/ZFP36L1/ATP6AP1/NRP1/DLG1/DUSP9/TIMP3/TPBG 17 GO:0048167 regulation of synaptic plasticity 11/742 198/18722 0.1639410744567 0.382554987159234 APP/MME/LGMN/NCSTN/PPP1R9A/SYT7/VAMP2/ERC1/EIF2AK4/CLN3/RAB11A 11 GO:0097529 myeloid leukocyte migration 12/742 220/18722 0.165158042759215 0.384764905498537 CSF3R/BSG/DUSP1/MIF/DPP4/FLT1/JAM3/CD81/ANXA1/LGMN/S100A9/PPIA 12 GO:0007215 glutamate receptor signaling pathway 4/742 54/18722 0.165355444205141 0.384764905498537 APP/NCSTN/GNAQ/CLN3 4 GO:0010524 positive regulation of calcium ion transport into cytosol 4/742 54/18722 0.165355444205141 0.384764905498537 CAV1/GSTO1/CALM1/CALM2 4 GO:0072348 sulfur compound transport 4/742 54/18722 0.165355444205141 0.384764905498537 SLC26A2/GJA1/SLC13A4/SLC19A3 4 GO:0072698 protein localization to microtubule cytoskeleton 4/742 54/18722 0.165355444205141 0.384764905498537 GOLGB1/CEP350/DIAPH1/PCM1 4 GO:1902743 regulation of lamellipodium organization 4/742 54/18722 0.165355444205141 0.384764905498537 KANK1/WASF2/CDC42/CAPZB 4 GO:0051480 regulation of cytosolic calcium ion concentration 18/742 353/18722 0.165672943873149 0.385322195260525 ATP2B1/LRP1/ITGAV/CAV1/GJA1/GSTO1/ATP2B4/DIAPH1/CD55/GTF2I/ADM/DDIT3/CALM1/CLN3/BCAP31/TGM2/CALM2/YWHAE 18 GO:0051302 regulation of cell division 10/742 177/18722 0.16591298549635 0.385698893342103 PKN2/YBX1/NCOA3/CALM1/CDC42/RHOA/IGF2/RAB11A/CALM2/LBH 10 GO:0002286 T cell activation involved in immune response 7/742 114/18722 0.166764936783238 0.387314897841653 CD46/RPS6/CD81/ANXA1/FOXP1/EIF2AK4/GATA3 7 GO:1901800 positive regulation of proteasomal protein catabolic process 7/742 114/18722 0.166764936783238 0.387314897841653 CAV1/TMEM259/HSPA1A/HSPA1B/HECTD1/BCAP31/DDA1 7 GO:0019216 regulation of lipid metabolic process 17/742 331/18722 0.166864238623234 0.38736341108965 PSAP/SF1/CAV1/ORMDL1/EGR1/FLT1/POR/CD81/ANXA1/ATP1A1/NCOR1/MBTPS1/ACADVL/ADM/ASAH1/CDC42/CGA 17 GO:0001764 neuron migration 9/742 156/18722 0.167273467312641 0.388131013867753 NRP2/ADGRG1/SEMA6A/NRP1/NR2F2/NIPBL/USP9X/PCM1/GATA3 9 GO:0006816 calcium ion transport 21/742 422/18722 0.169087412519825 0.391235478508827 AHNAK/ATP2B1/TPT1/ITGAV/KCNN4/CAV1/SLC3A2/GJA1/C4orf3/GSTO1/ATP2B4/SLC9A1/DIAPH1/TMEM165/SEC61A1/DDIT3/CALM1/VDAC1/RHOA/CALM2/YWHAE 21 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 6/742 94/18722 0.16931921218686 0.391235478508827 EGFR/CCNL1/NR2F2/SERTAD1/CKS1B/CCNE1 6 GO:0002042 cell migration involved in sprouting angiogenesis 6/742 94/18722 0.16931921218686 0.391235478508827 ITGB1/EPHB4/NRP1/MIA3/ANXA1/RHOA 6 GO:0006635 fatty acid beta-oxidation 5/742 74/18722 0.169614780587035 0.391235478508827 SLC27A2/CROT/ACADVL/HADHA/ETFA 5 GO:0009201 ribonucleoside triphosphate biosynthetic process 5/742 74/18722 0.169614780587035 0.391235478508827 ALDOA/TMSB4X/ENO1/NME3/PARP1 5 GO:0048332 mesoderm morphogenesis 5/742 74/18722 0.169614780587035 0.391235478508827 ITGB4/ITGB1/WLS/GJA1/BMP7 5 GO:0003230 cardiac atrium development 3/742 36/18722 0.169957760502013 0.391235478508827 SOX4/ISL1/GJA5 3 GO:0009225 nucleotide-sugar metabolic process 3/742 36/18722 0.169957760502013 0.391235478508827 EXTL2/FUT8/UGP2 3 GO:0010092 specification of animal organ identity 3/742 36/18722 0.169957760502013 0.391235478508827 LRP2/ISL1/GLI3 3 GO:0010762 regulation of fibroblast migration 3/742 36/18722 0.169957760502013 0.391235478508827 ITGB1/GNA12/CLN3 3 GO:0010923 negative regulation of phosphatase activity 3/742 36/18722 0.169957760502013 0.391235478508827 BOD1L1/PPP1R15A/ROCK1 3 GO:0042092 type 2 immune response 3/742 36/18722 0.169957760502013 0.391235478508827 CD81/ANXA1/GATA3 3 GO:0051955 regulation of amino acid transport 3/742 36/18722 0.169957760502013 0.391235478508827 ITGB1/SLC43A2/ARL6IP5 3 GO:0060251 regulation of glial cell proliferation 3/742 36/18722 0.169957760502013 0.391235478508827 EGFR/UFL1/HES1 3 GO:0071402 cellular response to lipoprotein particle stimulus 3/742 36/18722 0.169957760502013 0.391235478508827 ITGB1/MIA3/CD81 3 GO:0090313 regulation of protein targeting to membrane 3/742 36/18722 0.169957760502013 0.391235478508827 TCAF1/ANK3/STOM 3 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 3/742 36/18722 0.169957760502013 0.391235478508827 TPT1/MIF/RPL26 3 GO:0071675 regulation of mononuclear cell migration 7/742 115/18722 0.171962672941086 0.392564833075414 APP/DUSP1/CALR/MIA3/LGMN/DOCK8/RHOA 7 GO:0002523 leukocyte migration involved in inflammatory response 2/742 19/18722 0.172521913483142 0.392564833075414 JAM3/S100A9 2 GO:0002902 regulation of B cell apoptotic process 2/742 19/18722 0.172521913483142 0.392564833075414 SLC39A10/FOXP1 2 GO:0006007 glucose catabolic process 2/742 19/18722 0.172521913483142 0.392564833075414 LRP5/ENO1 2 GO:0006670 sphingosine metabolic process 2/742 19/18722 0.172521913483142 0.392564833075414 PLPP3/ASAH1 2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 2/742 19/18722 0.172521913483142 0.392564833075414 SOX4/RPL26 2 GO:0007530 sex determination 2/742 19/18722 0.172521913483142 0.392564833075414 SF1/CITED2 2 GO:0007603 phototransduction, visible light 2/742 19/18722 0.172521913483142 0.392564833075414 NMT1/GNAQ 2 GO:0010002 cardioblast differentiation 2/742 19/18722 0.172521913483142 0.392564833075414 ISL1/DHX36 2 GO:0015802 basic amino acid transport 2/742 19/18722 0.172521913483142 0.392564833075414 SLC38A9/CLN3 2 GO:0033194 response to hydroperoxide 2/742 19/18722 0.172521913483142 0.392564833075414 GPX3/GPX1 2 GO:0035728 response to hepatocyte growth factor 2/742 19/18722 0.172521913483142 0.392564833075414 NRP1/LGMN 2 GO:0036498 IRE1-mediated unfolded protein response 2/742 19/18722 0.172521913483142 0.392564833075414 HSPA5/UFL1 2 GO:0044003 modulation by symbiont of host process 2/742 19/18722 0.172521913483142 0.392564833075414 DAG1/SERPINB9 2 GO:0044827 modulation by host of viral genome replication 2/742 19/18722 0.172521913483142 0.392564833075414 STOM/EIF2AK4 2 GO:0046716 muscle cell cellular homeostasis 2/742 19/18722 0.172521913483142 0.392564833075414 GAA/ALDOA 2 GO:0051444 negative regulation of ubiquitin-protein transferase activity 2/742 19/18722 0.172521913483142 0.392564833075414 RPS20/RPL23 2 GO:0060216 definitive hemopoiesis 2/742 19/18722 0.172521913483142 0.392564833075414 TGFBR3/ADAR 2 GO:0061323 cell proliferation involved in heart morphogenesis 2/742 19/18722 0.172521913483142 0.392564833075414 ISL1/HES1 2 GO:0086014 atrial cardiac muscle cell action potential 2/742 19/18722 0.172521913483142 0.392564833075414 GJA1/GJA5 2 GO:0086026 atrial cardiac muscle cell to AV node cell signaling 2/742 19/18722 0.172521913483142 0.392564833075414 GJA1/GJA5 2 GO:0086066 atrial cardiac muscle cell to AV node cell communication 2/742 19/18722 0.172521913483142 0.392564833075414 GJA1/GJA5 2 GO:0098780 response to mitochondrial depolarisation 2/742 19/18722 0.172521913483142 0.392564833075414 VPS13C/HUWE1 2 GO:1903978 regulation of microglial cell activation 2/742 19/18722 0.172521913483142 0.392564833075414 GRN/CTSC 2 GO:2000251 positive regulation of actin cytoskeleton reorganization 2/742 19/18722 0.172521913483142 0.392564833075414 NRP1/CDC42 2 GO:0003179 heart valve morphogenesis 4/742 55/18722 0.173138967382301 0.393787522499339 SOX4/GJA5/ROCK1/GATA3 4 GO:0001936 regulation of endothelial cell proliferation 10/742 179/18722 0.174154748327116 0.395551474361358 NRP2/CAV1/GJA1/FLT1/NRP1/NR2F2/NF1/MYDGF/EMC10/IGF2 10 GO:0010950 positive regulation of endopeptidase activity 10/742 179/18722 0.174154748327116 0.395551474361358 CTSD/ARL6IP5/ASPH/LGMN/NCSTN/S100A9/PMAIP1/BCAP31/RHOA/PSME2 10 GO:1901991 negative regulation of mitotic cell cycle phase transition 10/742 179/18722 0.174154748327116 0.395551474361358 DUSP1/SOX4/RPL26/PRKDC/ZFP36L1/TPR/DLG1/CTDSPL/BRD7/LCMT1 10 GO:0050764 regulation of phagocytosis 6/742 95/18722 0.175139550361661 0.397605413045314 LRP1/ITGAV/CALR/LMAN2/SYT7/TGM2 6 GO:0006024 glycosaminoglycan biosynthetic process 5/742 75/18722 0.176252183324878 0.39939714936922 CHPF/HEXA/B4GAT1/B3GAT3/CLTC 5 GO:0006278 RNA-dependent DNA biosynthetic process 5/742 75/18722 0.176252183324878 0.39939714936922 HNRNPA1/RAD50/HNRNPC/PTGES3/CCT3 5 GO:0033077 T cell differentiation in thymus 5/742 75/18722 0.176252183324878 0.39939714936922 RPS6/PRKDC/ZFP36L1/GLI3/GATA3 5 GO:0051453 regulation of intracellular pH 5/742 75/18722 0.176252183324878 0.39939714936922 GRN/SLC9A1/ATP6AP2/TMEM165/CLN3 5 GO:0007006 mitochondrial membrane organization 7/742 116/18722 0.177229904012011 0.401231957793063 HSPA1A/SLC9A1/PMAIP1/NMT1/CALM1/VDAC2/DYNLT1 7 GO:0010977 negative regulation of neuron projection development 8/742 137/18722 0.177305539243372 0.401231957793063 LRP1/SEMA6A/KANK1/SEMA6D/RTN4/NRP1/THOC2/RHOA 8 GO:0055123 digestive system development 8/742 137/18722 0.177305539243372 0.401231957793063 EGFR/WLS/LGR4/IL6ST/GLI3/NIPBL/HES1/IGF2 8 GO:0001894 tissue homeostasis 14/742 268/18722 0.179261414503382 0.404458840881211 EGFR/SLC2A1/ITGB1/LAMC1/TFRC/GJA1/LSR/ATP6AP1/JAM3/ACTG1/NF1/LTBP3/EPAS1/HSPB1 14 GO:0000819 sister chromatid segregation 11/742 202/18722 0.179533954260274 0.404458840881211 DUSP1/ATRX/TPR/NIPBL/KPNB1/RAN/NEK6/RAB11A/ANAPC11/UBE2C/LCMT1 11 GO:0009913 epidermal cell differentiation 11/742 202/18722 0.179533954260274 0.404458840881211 PLEC/DSP/ZFP36L1/ANXA1/ROCK1/TRIOBP/ST14/NCOA3/ASAH1/SRSF6/HES1 11 GO:0016051 carbohydrate biosynthetic process 11/742 202/18722 0.179533954260274 0.404458840881211 AGL/TPI1/DDB1/RANBP2/ISYNA1/FUT8/SLC35B4/CLTC/PTGES3/IGF2/UGP2 11 GO:0002369 T cell cytokine production 3/742 37/18722 0.179877747655065 0.404458840881211 CD81/CD55/GATA3 3 GO:0002724 regulation of T cell cytokine production 3/742 37/18722 0.179877747655065 0.404458840881211 CD81/CD55/GATA3 3 GO:0006862 nucleotide transport 3/742 37/18722 0.179877747655065 0.404458840881211 GJA1/SLC19A1/SLC25A36 3 GO:0048009 insulin-like growth factor receptor signaling pathway 3/742 37/18722 0.179877747655065 0.404458840881211 CRIM1/IGF1R/PHIP 3 GO:0050775 positive regulation of dendrite morphogenesis 3/742 37/18722 0.179877747655065 0.404458840881211 CUX1/DHX36/OBSL1 3 GO:0051294 establishment of spindle orientation 3/742 37/18722 0.179877747655065 0.404458840881211 ITGB1/GJA1/DYNLT1 3 GO:0051567 histone H3-K9 methylation 3/742 37/18722 0.179877747655065 0.404458840881211 ATRX/ASH1L/RIF1 3 GO:0060416 response to growth hormone 3/742 37/18722 0.179877747655065 0.404458840881211 CSH1/LEPROT/CACYBP 3 GO:0090218 positive regulation of lipid kinase activity 3/742 37/18722 0.179877747655065 0.404458840881211 FLT1/CD81/CDC42 3 GO:1904358 positive regulation of telomere maintenance via telomere lengthening 3/742 37/18722 0.179877747655065 0.404458840881211 HNRNPA1/DHX36/CCT3 3 GO:1903169 regulation of calcium ion transmembrane transport 9/742 159/18722 0.180639583239553 0.405608871578234 AHNAK/C4orf3/GSTO1/SLC9A1/DIAPH1/CALM1/VDAC1/CALM2/YWHAE 9 GO:0051304 chromosome separation 6/742 96/18722 0.181040487875967 0.405608871578234 DUSP1/TPR/NEK6/ANAPC11/UBE2C/LCMT1 6 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 4/742 56/18722 0.181046065147775 0.405608871578234 ZFP36L1/TNRC6A/TNRC6B/DHX36 4 GO:0030166 proteoglycan biosynthetic process 4/742 56/18722 0.181046065147775 0.405608871578234 EXTL2/CHPF/B3GAT3/TCF7L2 4 GO:0046456 icosanoid biosynthetic process 4/742 56/18722 0.181046065147775 0.405608871578234 MGST3/MIF/ANXA1/PTGES3 4 GO:0048008 platelet-derived growth factor receptor signaling pathway 4/742 56/18722 0.181046065147775 0.405608871578234 LRP1/NRP1/PTPN12/ARID5B 4 GO:0051058 negative regulation of small GTPase mediated signal transduction 4/742 56/18722 0.181046065147775 0.405608871578234 ITGB1/MET/KANK1/RASA1 4 GO:0051784 negative regulation of nuclear division 4/742 56/18722 0.181046065147775 0.405608871578234 DUSP1/BMP7/TPR/LCMT1 4 GO:0001937 negative regulation of endothelial cell proliferation 5/742 76/18722 0.182986409521146 0.409398941591694 CAV1/GJA1/FLT1/NR2F2/NF1 5 GO:0021536 diencephalon development 5/742 76/18722 0.182986409521146 0.409398941591694 NRP2/CDH1/NRP1/ISL1/HES1 5 GO:0045685 regulation of glial cell differentiation 5/742 76/18722 0.182986409521146 0.409398941591694 SPINT1/DAG1/IL6ST/NF1/HES1 5 GO:0050670 regulation of lymphocyte proliferation 12/742 225/18722 0.183763635365473 0.410951724176295 CD46/SLC39A10/TFRC/MIF/IL6ST/DLG5/CD81/ANXA1/DLG1/CD55/HES1/IGF2 12 GO:0007018 microtubule-based movement 19/742 382/18722 0.184105631712771 0.411530235593253 ARMCX3/APP/KTN1/DYNC1H1/DST/ATP2B4/ARHGAP21/KIF5B/ASH1L/PURA/IFT27/LAMP1/PCM1/KPNB1/HSPB1/CLN3/DYNLRB1/CDC42/DYNLT1 19 GO:0044270 cellular nitrogen compound catabolic process 22/742 451/18722 0.185494558049931 0.413367855622264 KCNQ1OT1/FUS/ZFP36L1/NPM1/POR/TNRC6A/HSPA1A/UPF2/TNRC6B/YBX1/HSPA1B/ROCK1/PUM1/TET2/DHX36/CELF1/LARP1/CIRBP/DDX5/HNRNPC/SSB/BLVRA 22 GO:0060401 cytosolic calcium ion transport 10/742 182/18722 0.186869157359502 0.413367855622264 ATP2B1/CAV1/GSTO1/ATP2B4/DIAPH1/DDIT3/CALM1/VDAC1/CALM2/YWHAE 10 GO:0006525 arginine metabolic process 2/742 20/18722 0.186938333400918 0.413367855622264 ATP2B4/CLN3 2 GO:0006607 NLS-bearing protein import into nucleus 2/742 20/18722 0.186938333400918 0.413367855622264 RANBP2/KPNB1 2 GO:0006883 cellular sodium ion homeostasis 2/742 20/18722 0.186938333400918 0.413367855622264 SLC9A1/ATP1A1 2 GO:0006896 Golgi to vacuole transport 2/742 20/18722 0.186938333400918 0.413367855622264 LAMP1/CLN3 2 GO:0010042 response to manganese ion 2/742 20/18722 0.186938333400918 0.413367855622264 HSPA5/APP 2 GO:0016553 base conversion or substitution editing 2/742 20/18722 0.186938333400918 0.413367855622264 RBM47/ADAR 2 GO:0031498 chromatin disassembly 2/742 20/18722 0.186938333400918 0.413367855622264 ARID1A/HMGA1 2 GO:0032211 negative regulation of telomere maintenance via telomerase 2/742 20/18722 0.186938333400918 0.413367855622264 HNRNPA1/HNRNPC 2 GO:0032332 positive regulation of chondrocyte differentiation 2/742 20/18722 0.186938333400918 0.413367855622264 POR/GLI3 2 GO:0043586 tongue development 2/742 20/18722 0.186938333400918 0.413367855622264 EGFR/GLI3 2 GO:0046931 pore complex assembly 2/742 20/18722 0.186938333400918 0.413367855622264 RTN4/CCT3 2 GO:0060044 negative regulation of cardiac muscle cell proliferation 2/742 20/18722 0.186938333400918 0.413367855622264 GJA1/CITED2 2 GO:0060252 positive regulation of glial cell proliferation 2/742 20/18722 0.186938333400918 0.413367855622264 EGFR/UFL1 2 GO:0071731 response to nitric oxide 2/742 20/18722 0.186938333400918 0.413367855622264 MTR/TXN 2 GO:0072567 chemokine (C-X-C motif) ligand 2 production 2/742 20/18722 0.186938333400918 0.413367855622264 LRP1/FOXP1 2 GO:0097150 neuronal stem cell population maintenance 2/742 20/18722 0.186938333400918 0.413367855622264 PCM1/HES1 2 GO:1901679 nucleotide transmembrane transport 2/742 20/18722 0.186938333400918 0.413367855622264 SLC19A1/SLC25A36 2 GO:1903206 negative regulation of hydrogen peroxide-induced cell death 2/742 20/18722 0.186938333400918 0.413367855622264 MET/TXN 2 GO:1903817 negative regulation of voltage-gated potassium channel activity 2/742 20/18722 0.186938333400918 0.413367855622264 CAV1/ANK3 2 GO:1990182 exosomal secretion 2/742 20/18722 0.186938333400918 0.413367855622264 RAB11A/SDCBP 2 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production 2/742 20/18722 0.186938333400918 0.413367855622264 LRP1/FOXP1 2 GO:2000678 negative regulation of transcription regulatory region DNA binding 2/742 20/18722 0.186938333400918 0.413367855622264 TMSB4X/DDIT3 2 GO:0035335 peptidyl-tyrosine dephosphorylation 6/742 97/18722 0.187019667472826 0.413367855622264 DUSP1/DUSP6/PTPRF/PTPRA/PTPN12/PTPN14 6 GO:0002011 morphogenesis of an epithelial sheet 4/742 57/18722 0.189070414867887 0.415567834235266 DAG1/BMP7/FERMT1/RHOA 4 GO:0006754 ATP biosynthetic process 4/742 57/18722 0.189070414867887 0.415567834235266 ALDOA/TMSB4X/ENO1/PARP1 4 GO:0010883 regulation of lipid storage 4/742 57/18722 0.189070414867887 0.415567834235266 ITGAV/PLIN2/NFKBIA/MEST 4 GO:0016447 somatic recombination of immunoglobulin gene segments 4/742 57/18722 0.189070414867887 0.415567834235266 TFRC/PRKDC/RIF1/YY1 4 GO:0051785 positive regulation of nuclear division 4/742 57/18722 0.189070414867887 0.415567834235266 LRP5/PHIP/IGF2/ANAPC11 4 GO:0060042 retina morphogenesis in camera-type eye 4/742 57/18722 0.189070414867887 0.415567834235266 LRP5/NAGLU/MAN2A1/OBSL1 4 GO:0061756 leukocyte adhesion to vascular endothelial cell 4/742 57/18722 0.189070414867887 0.415567834235266 ITGB1/NFAT5/ROCK1/RHOA 4 GO:0002200 somatic diversification of immune receptors 5/742 77/18722 0.189813795442554 0.415567834235266 TFRC/PRKDC/RIF1/ADAR/YY1 5 GO:0048644 muscle organ morphogenesis 5/742 77/18722 0.189813795442554 0.415567834235266 LRP2/TGFBR3/DSP/ISL1/ARID5B 5 GO:0001825 blastocyst formation 3/742 38/18722 0.189949831923731 0.415567834235266 RTN4/JUNB/CITED2 3 GO:0006882 cellular zinc ion homeostasis 3/742 38/18722 0.189949831923731 0.415567834235266 SLC39A10/S100A9/SLC39A7 3 GO:0007094 mitotic spindle assembly checkpoint signaling 3/742 38/18722 0.189949831923731 0.415567834235266 DUSP1/TPR/LCMT1 3 GO:0032373 positive regulation of sterol transport 3/742 38/18722 0.189949831923731 0.415567834235266 LRP1/CAV1/NFKBIA 3 GO:0032376 positive regulation of cholesterol transport 3/742 38/18722 0.189949831923731 0.415567834235266 LRP1/CAV1/NFKBIA 3 GO:0032717 negative regulation of interleukin-8 production 3/742 38/18722 0.189949831923731 0.415567834235266 TMSB4X/ANXA1/ANXA4 3 GO:0035886 vascular associated smooth muscle cell differentiation 3/742 38/18722 0.189949831923731 0.415567834235266 ADM/HES1/PDCD4 3 GO:0046329 negative regulation of JNK cascade 3/742 38/18722 0.189949831923731 0.415567834235266 NCOR1/MARVELD3/PDCD4 3 GO:0048713 regulation of oligodendrocyte differentiation 3/742 38/18722 0.189949831923731 0.415567834235266 DAG1/NF1/HES1 3 GO:0071173 spindle assembly checkpoint signaling 3/742 38/18722 0.189949831923731 0.415567834235266 DUSP1/TPR/LCMT1 3 GO:0071174 mitotic spindle checkpoint signaling 3/742 38/18722 0.189949831923731 0.415567834235266 DUSP1/TPR/LCMT1 3 GO:1901031 regulation of response to reactive oxygen species 3/742 38/18722 0.189949831923731 0.415567834235266 MET/BMP7/TXN 3 GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 3/742 38/18722 0.189949831923731 0.415567834235266 HSPA1A/NMT1/VDAC2 3 GO:1903580 positive regulation of ATP metabolic process 3/742 38/18722 0.189949831923731 0.415567834235266 APP/TMSB4X/ENO1 3 GO:0032944 regulation of mononuclear cell proliferation 12/742 227/18722 0.191472706209403 0.418528835696659 CD46/SLC39A10/TFRC/MIF/IL6ST/DLG5/CD81/ANXA1/DLG1/CD55/HES1/IGF2 12 GO:0046777 protein autophosphorylation 12/742 227/18722 0.191472706209403 0.418528835696659 EGFR/AAK1/CAV1/IQGAP1/EPHB4/FLT1/IGF1R/EIF2AK4/RAD50/CALM1/NEK6/CALM2 12 GO:0010948 negative regulation of cell cycle process 15/742 294/18722 0.191750705692332 0.418951121680725 DUSP1/ATRX/SOX4/RPL26/PRKDC/ZFP36L1/PPP1R10/NPM1/BMP7/TPR/DLG1/CTDSPL/EIF2AK4/BRD7/LCMT1 15 GO:1904029 regulation of cyclin-dependent protein kinase activity 6/742 98/18722 0.193074683375596 0.421657354498429 EGFR/CCNL1/NR2F2/SERTAD1/CKS1B/CCNE1 6 GO:0030282 bone mineralization 7/742 119/18722 0.193432221145078 0.422251512353815 FBN2/ATP2B1/LGR4/BMP7/LTBP3/NOTUM/ATRAID 7 GO:0017038 protein import 11/742 206/18722 0.195795763398103 0.427222204587733 CDH1/RPL23/PPP1R10/TPR/FERMT1/GLI3/RANBP2/LAMP2/NFKBIA/KPNB1/RAN 11 GO:0070661 leukocyte proliferation 16/742 318/18722 0.196624368158903 0.428594788123052 CD46/SLC39A10/RPS6/TFRC/MIF/IL6ST/DLG5/CD81/ANXA1/NCSTN/DLG1/CD55/PURA/DOCK8/HES1/IGF2 16 GO:0034637 cellular carbohydrate biosynthetic process 5/742 78/18722 0.196730624064722 0.428594788123052 AGL/ISYNA1/PTGES3/IGF2/UGP2 5 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 5/742 78/18722 0.196730624064722 0.428594788123052 DHCR24/POR/GPX1/SIAH2/SERPINB9 5 GO:0048284 organelle fusion 8/742 141/18722 0.197175092542679 0.428594788123052 TFRC/EEA1/ANXA1/KIF5B/SYT7/VAMP2/HUWE1/CLN3 8 GO:0002763 positive regulation of myeloid leukocyte differentiation 4/742 58/18722 0.197205658583744 0.428594788123052 JUN/FOS/ZFP36L1/ATP6AP1 4 GO:0006826 iron ion transport 4/742 58/18722 0.197205658583744 0.428594788123052 FTH1/TFRC/SLC40A1/CLTC 4 GO:0010559 regulation of glycoprotein biosynthetic process 4/742 58/18722 0.197205658583744 0.428594788123052 ITM2B/TMEM59/NCSTN/TCF7L2 4 GO:0044380 protein localization to cytoskeleton 4/742 58/18722 0.197205658583744 0.428594788123052 GOLGB1/CEP350/DIAPH1/PCM1 4 GO:1902808 positive regulation of cell cycle G1/S phase transition 4/742 58/18722 0.197205658583744 0.428594788123052 EGFR/ADAMTS1/ANXA1/EIF4G1 4 GO:0006304 DNA modification 7/742 120/18722 0.198960890948305 0.431876148904977 FOS/ATRX/MPHOSPH8/USP9X/TET2/GATA3/PARP1 7 GO:0071901 negative regulation of protein serine/threonine kinase activity 7/742 120/18722 0.198960890948305 0.431876148904977 DUSP1/CAV1/LRP5/BMP7/NR2F2/NF1/PDCD4 7 GO:0010717 regulation of epithelial to mesenchymal transition 6/742 99/18722 0.199203085274601 0.431876148904977 DAG1/BMP7/ISL1/TCF7L2/GATA3/SDCBP 6 GO:0030838 positive regulation of actin filament polymerization 6/742 99/18722 0.199203085274601 0.431876148904977 IQGAP2/PFN1/DLG1/WASF2/ARPC3/RHOA 6 GO:0071356 cellular response to tumor necrosis factor 12/742 229/18722 0.19932810031786 0.431876148904977 ZFP36L1/KRT8/TMSB4X/HSPA1A/ACTN4/HSPA1B/SPPL2B/ASAH1/NFKBIA/KRT18/GATA3/EIF5A 12 GO:0007618 mating 3/742 39/18722 0.200160967689993 0.431876148904977 APP/SLC6A4/HEXB 3 GO:0031577 spindle checkpoint signaling 3/742 39/18722 0.200160967689993 0.431876148904977 DUSP1/TPR/LCMT1 3 GO:0034314 Arp2/3 complex-mediated actin nucleation 3/742 39/18722 0.200160967689993 0.431876148904977 IQGAP2/WASF2/ARPC3 3 GO:0045823 positive regulation of heart contraction 3/742 39/18722 0.200160967689993 0.431876148904977 ADRB1/ATP1A1/ADM 3 GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 3/742 39/18722 0.200160967689993 0.431876148904977 CD81/ANXA1/CD55 3 GO:0000002 mitochondrial genome maintenance 2/742 21/18722 0.201513061381776 0.431876148904977 SLC25A36/PARP1 2 GO:0006925 inflammatory cell apoptotic process 2/742 21/18722 0.201513061381776 0.431876148904977 CTSL/ANXA1 2 GO:0007252 I-kappaB phosphorylation 2/742 21/18722 0.201513061381776 0.431876148904977 ERC1/PRDX4 2 GO:0007350 blastoderm segmentation 2/742 21/18722 0.201513061381776 0.431876148904977 NRP2/NRP1 2 GO:0007617 mating behavior 2/742 21/18722 0.201513061381776 0.431876148904977 APP/HEXB 2 GO:0030449 regulation of complement activation 2/742 21/18722 0.201513061381776 0.431876148904977 CD46/CD55 2 GO:0031145 anaphase-promoting complex-dependent catabolic process 2/742 21/18722 0.201513061381776 0.431876148904977 ANAPC11/UBE2C 2 GO:0032288 myelin assembly 2/742 21/18722 0.201513061381776 0.431876148904977 ITGB4/GPC1 2 GO:0034035 purine ribonucleoside bisphosphate metabolic process 2/742 21/18722 0.201513061381776 0.431876148904977 SLC26A2/TPST2 2 GO:0046519 sphingoid metabolic process 2/742 21/18722 0.201513061381776 0.431876148904977 PLPP3/ASAH1 2 GO:0046641 positive regulation of alpha-beta T cell proliferation 2/742 21/18722 0.201513061381776 0.431876148904977 CD81/CD55 2 GO:0048745 smooth muscle tissue development 2/742 21/18722 0.201513061381776 0.431876148904977 NF1/DLG1 2 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process 2/742 21/18722 0.201513061381776 0.431876148904977 SLC26A2/TPST2 2 GO:0071498 cellular response to fluid shear stress 2/742 21/18722 0.201513061381776 0.431876148904977 PLEC/TFPI2 2 GO:0072170 metanephric tubule development 2/742 21/18722 0.201513061381776 0.431876148904977 LGR4/HES1 2 GO:0072243 metanephric nephron epithelium development 2/742 21/18722 0.201513061381776 0.431876148904977 LGR4/HES1 2 GO:0097734 extracellular exosome biogenesis 2/742 21/18722 0.201513061381776 0.431876148904977 RAB11A/SDCBP 2 GO:0099515 actin filament-based transport 2/742 21/18722 0.201513061381776 0.431876148904977 SYNE2/ACTN4 2 GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2/742 21/18722 0.201513061381776 0.431876148904977 HSPA1A/NMT1 2 GO:1902259 regulation of delayed rectifier potassium channel activity 2/742 21/18722 0.201513061381776 0.431876148904977 ANK3/VAMP2 2 GO:1902473 regulation of protein localization to synapse 2/742 21/18722 0.201513061381776 0.431876148904977 DAG1/DLG1 2 GO:2000774 positive regulation of cellular senescence 2/742 21/18722 0.201513061381776 0.431876148904977 YPEL3/HMGA1 2 GO:0061448 connective tissue development 13/742 252/18722 0.202032824503456 0.432802321356059 EFEMP1/GLG1/TRIP11/EGR1/SERPINH1/LRP5/BMP7/POR/ESRRA/GLI3/LTBP3/CREB3L2/ARID5B 13 GO:0006023 aminoglycan biosynthetic process 5/742 79/18722 0.203733132451378 0.435877728154962 CHPF/HEXA/B4GAT1/B3GAT3/CLTC 5 GO:0006029 proteoglycan metabolic process 5/742 79/18722 0.203733132451378 0.435877728154962 EXTL2/CHPF/GPC1/B3GAT3/TCF7L2 5 GO:0050772 positive regulation of axonogenesis 5/742 79/18722 0.203733132451378 0.435877728154962 LRP1/GOLGA4/MACF1/NRP1/RAB11A 5 GO:0050806 positive regulation of synaptic transmission 9/742 164/18722 0.203931095573939 0.43611238620574 EGFR/APP/MME/KIF5B/LGMN/NCSTN/PPP1R9A/VAMP2/EIF2AK4 9 GO:0043500 muscle adaptation 7/742 121/18722 0.20455059796194 0.436869846057926 DAG1/IL6ST/ATP2B4/SLC9A1/ROCK1/PARP1/YY1 7 GO:0048706 embryonic skeletal system development 7/742 121/18722 0.20455059796194 0.436869846057926 PBX1/BMP7/GLI3/KIAA1217/DLG1/NIPBL/SLC39A1 7 GO:1904019 epithelial cell apoptotic process 7/742 121/18722 0.20455059796194 0.436869846057926 ZFP36L1/KRT8/TCF7L2/SRSF6/KRT18/GATA3/PDCD4 7 GO:0006664 glycolipid metabolic process 6/742 100/18722 0.205402382272927 0.437834497662204 HEXA/FUCA1/GPAA1/GLB1/PGAP1/HEXB 6 GO:0006406 mRNA export from nucleus 4/742 59/18722 0.205445418133803 0.437834497662204 TPR/PABPN1/UPF2/THOC2 4 GO:0019369 arachidonic acid metabolic process 4/742 59/18722 0.205445418133803 0.437834497662204 GPX1/PTGES3/CYP2J2/GPX4 4 GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus 4/742 59/18722 0.205445418133803 0.437834497662204 TPR/PABPN1/UPF2/THOC2 4 GO:0071806 protein transmembrane transport 4/742 59/18722 0.205445418133803 0.437834497662204 HSPA5/SEC62/SEC61A1/SEC63 4 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 11/742 209/18722 0.208407006854358 0.443954555351672 CTSD/DHCR24/POR/ARL6IP5/S100A9/PMAIP1/GPX1/SIAH2/BCAP31/SERPINB9/RHOA 11 GO:0006839 mitochondrial transport 13/742 254/18722 0.209697989503367 0.446101128984393 LMAN1/HSPA1A/SLC25A36/SLC9A1/PMAIP1/NMT1/HUWE1/VDAC1/BCAP31/LEPROT/UBE2L3/VDAC2/DYNLT1 13 GO:0051208 sequestering of calcium ion 7/742 122/18722 0.210199546413135 0.446101128984393 HSP90B1/GSTO1/CALR/DIAPH1/DDIT3/CALM1/CALM2 7 GO:0007339 binding of sperm to zona pellucida 3/742 40/18722 0.210498326247494 0.446101128984393 ALDOA/VDAC2/CCT3 3 GO:0010863 positive regulation of phospholipase C activity 3/742 40/18722 0.210498326247494 0.446101128984393 EGFR/FLT1/GNAQ 3 GO:0045777 positive regulation of blood pressure 3/742 40/18722 0.210498326247494 0.446101128984393 NR2F2/ADRB1/RHOA 3 GO:0045841 negative regulation of mitotic metaphase/anaphase transition 3/742 40/18722 0.210498326247494 0.446101128984393 DUSP1/TPR/LCMT1 3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 3/742 40/18722 0.210498326247494 0.446101128984393 GSTO1/CALM1/CALM2 3 GO:0055069 zinc ion homeostasis 3/742 40/18722 0.210498326247494 0.446101128984393 SLC39A10/S100A9/SLC39A7 3 GO:0071276 cellular response to cadmium ion 3/742 40/18722 0.210498326247494 0.446101128984393 JUN/EGFR/FOS 3 GO:0097352 autophagosome maturation 3/742 40/18722 0.210498326247494 0.446101128984393 LAMP2/CALM1/CLN3 3 GO:1901998 toxin transport 3/742 40/18722 0.210498326247494 0.446101128984393 HSPA5/NRP1/CCT3 3 GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 3/742 40/18722 0.210498326247494 0.446101128984393 HSPA1A/NMT1/VDAC2 3 GO:0021766 hippocampus development 5/742 80/18722 0.210817518940351 0.446203317722936 ATP2B4/CDK6/GLI3/KIF5B/ANXA3 5 GO:0048145 regulation of fibroblast proliferation 5/742 80/18722 0.210817518940351 0.446203317722936 FTH1/MIF/PRKDC/CDK6/NF1 5 GO:1901264 carbohydrate derivative transport 5/742 80/18722 0.210817518940351 0.446203317722936 PSAP/GJA1/SLC19A1/SLC35B4/CLN3 5 GO:0009150 purine ribonucleotide metabolic process 18/742 368/18722 0.211093057083839 0.446595161453604 GAPDH/SLC26A2/APP/LDHA/ALDOA/ACSS1/TPST2/TMSB4X/TPI1/CROT/ENO1/DLG1/NCOR1/NME3/PKM/PARP1/RAN/RHOA 18 GO:1903509 liposaccharide metabolic process 6/742 101/18722 0.211670046784741 0.447624157156088 HEXA/FUCA1/GPAA1/GLB1/PGAP1/HEXB 6 GO:0014065 phosphatidylinositol 3-kinase signaling 8/742 144/18722 0.212647668030459 0.449499135674141 EGFR/ZFP36L1/FLT1/IGF1R/NF1/MYDGF/ERBB3/GATA3 8 GO:0048839 inner ear development 10/742 188/18722 0.213489024669306 0.45055014881733 LGR5/TRIP11/NAGLU/GLI3/LRP10/TRIOBP/IFT27/ATP6V1B1/GATA3/HES1 10 GO:0051924 regulation of calcium ion transport 13/742 255/18722 0.213577904656581 0.45055014881733 AHNAK/ATP2B1/CAV1/GJA1/C4orf3/GSTO1/SLC9A1/DIAPH1/CALM1/VDAC1/RHOA/CALM2/YWHAE 13 GO:0002712 regulation of B cell mediated immunity 4/742 60/18722 0.213783309479316 0.45055014881733 CD46/TFRC/CD55/RIF1 4 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 4/742 60/18722 0.213783309479316 0.45055014881733 HSPA1A/HSPA1B/PUM1/NFKBIA 4 GO:0002889 regulation of immunoglobulin mediated immune response 4/742 60/18722 0.213783309479316 0.45055014881733 CD46/TFRC/CD55/RIF1 4 GO:0051851 modulation by host of symbiont process 4/742 60/18722 0.213783309479316 0.45055014881733 JUN/STOM/CFL1/EIF2AK4 4 GO:0055008 cardiac muscle tissue morphogenesis 4/742 60/18722 0.213783309479316 0.45055014881733 LRP2/TGFBR3/DSP/ISL1 4 GO:0007059 chromosome segregation 17/742 346/18722 0.214068606512338 0.450959026085693 DYNC1H1/DUSP1/ATRX/TPR/NIPBL/PUM1/USP9X/KPNB1/RAN/CDC42/NEK6/RAB11A/ANAPC11/UBE2C/LCMT1/CCNE1/BANF1 17 GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization 2/742 22/18722 0.216210966505961 0.451238772513496 SPESP1/FOLR1 2 GO:0007398 ectoderm development 2/742 22/18722 0.216210966505961 0.451238772513496 TPT1/ITGA6 2 GO:0007413 axonal fasciculation 2/742 22/18722 0.216210966505961 0.451238772513496 RTN4/NRP1 2 GO:0008211 glucocorticoid metabolic process 2/742 22/18722 0.216210966505961 0.451238772513496 ATP1A1/CYP11A1 2 GO:0016137 glycoside metabolic process 2/742 22/18722 0.216210966505961 0.451238772513496 FUCA1/GUSB 2 GO:0021854 hypothalamus development 2/742 22/18722 0.216210966505961 0.451238772513496 NRP2/NRP1 2 GO:0032069 regulation of nuclease activity 2/742 22/18722 0.216210966505961 0.451238772513496 NPM1/HSPA1A 2 GO:0032891 negative regulation of organic acid transport 2/742 22/18722 0.216210966505961 0.451238772513496 SLC43A2/ARL6IP5 2 GO:0034629 cellular protein-containing complex localization 2/742 22/18722 0.216210966505961 0.451238772513496 AKAP9/DLG1 2 GO:0035357 peroxisome proliferator activated receptor signaling pathway 2/742 22/18722 0.216210966505961 0.451238772513496 ACTN4/CITED2 2 GO:0045061 thymic T cell selection 2/742 22/18722 0.216210966505961 0.451238772513496 GLI3/GATA3 2 GO:0045540 regulation of cholesterol biosynthetic process 2/742 22/18722 0.216210966505961 0.451238772513496 POR/MBTPS1 2 GO:0048169 regulation of long-term neuronal synaptic plasticity 2/742 22/18722 0.216210966505961 0.451238772513496 APP/RAB11A 2 GO:0051220 cytoplasmic sequestering of protein 2/742 22/18722 0.216210966505961 0.451238772513496 TMSB4X/NFKBIA 2 GO:0060444 branching involved in mammary gland duct morphogenesis 2/742 22/18722 0.216210966505961 0.451238772513496 LRP5/KDM5B 2 GO:0060563 neuroepithelial cell differentiation 2/742 22/18722 0.216210966505961 0.451238772513496 SOX4/HES1 2 GO:0071404 cellular response to low-density lipoprotein particle stimulus 2/742 22/18722 0.216210966505961 0.451238772513496 ITGB1/CD81 2 GO:0106030 neuron projection fasciculation 2/742 22/18722 0.216210966505961 0.451238772513496 RTN4/NRP1 2 GO:0106118 regulation of sterol biosynthetic process 2/742 22/18722 0.216210966505961 0.451238772513496 POR/MBTPS1 2 GO:1900120 regulation of receptor binding 2/742 22/18722 0.216210966505961 0.451238772513496 NRP1/PTPRF 2 GO:1900543 negative regulation of purine nucleotide metabolic process 2/742 22/18722 0.216210966505961 0.451238772513496 NCOR1/PARP1 2 GO:1901032 negative regulation of response to reactive oxygen species 2/742 22/18722 0.216210966505961 0.451238772513496 MET/TXN 2 GO:0001942 hair follicle development 5/742 81/18722 0.217979950127713 0.454020818211234 EGFR/LAMA5/LGR5/LGR4/FERMT1 5 GO:0048144 fibroblast proliferation 5/742 81/18722 0.217979950127713 0.454020818211234 FTH1/MIF/PRKDC/CDK6/NF1 5 GO:0006672 ceramide metabolic process 6/742 102/18722 0.218003518379969 0.454020818211234 HEXA/ORMDL1/PLPP3/DEGS1/ASAH1/HEXB 6 GO:0032677 regulation of interleukin-8 production 6/742 102/18722 0.218003518379969 0.454020818211234 TMSB4X/HSPA1A/ANXA1/HSPA1B/DDIT3/ANXA4 6 GO:0035710 CD4-positive, alpha-beta T cell activation 6/742 102/18722 0.218003518379969 0.454020818211234 CTSL/CD81/ANXA1/CD55/FOXP1/GATA3 6 GO:0051056 regulation of small GTPase mediated signal transduction 15/742 302/18722 0.219905327760717 0.457788587921595 ADGRG1/ITGAV/ITGB1/MET/KANK1/NRP1/ARHGAP21/AKAP13/RASA1/SYDE2/ARHGAP5/DOCK8/TGM2/EPS8L1/DYNLT1 15 GO:0010907 positive regulation of glucose metabolic process 3/742 41/18722 0.220949321835549 0.45860909658303 DDB1/PMAIP1/IGF2 3 GO:0031062 positive regulation of histone methylation 3/742 41/18722 0.220949321835549 0.45860909658303 BRD4/RIF1/RTF1 3 GO:0050856 regulation of T cell receptor signaling pathway 3/742 41/18722 0.220949321835549 0.45860909658303 KCNN4/CD81/PHPT1 3 GO:0070296 sarcoplasmic reticulum calcium ion transport 3/742 41/18722 0.220949321835549 0.45860909658303 GSTO1/CALM1/CALM2 3 GO:1900371 regulation of purine nucleotide biosynthetic process 3/742 41/18722 0.220949321835549 0.45860909658303 TMSB4X/ENO1/PARP1 3 GO:1903524 positive regulation of blood circulation 3/742 41/18722 0.220949321835549 0.45860909658303 ADRB1/ATP1A1/ADM 3 GO:1905314 semi-lunar valve development 3/742 41/18722 0.220949321835549 0.45860909658303 GJA5/ROCK1/GATA3 3 GO:0043030 regulation of macrophage activation 4/742 61/18722 0.222212956241213 0.460458055298486 GRN/JUND/CTSC/MIF 4 GO:0043954 cellular component maintenance 4/742 61/18722 0.222212956241213 0.460458055298486 IGF1R/DLG1/ERC1/SDF4 4 GO:0060997 dendritic spine morphogenesis 4/742 61/18722 0.222212956241213 0.460458055298486 PPP1R9A/CFL1/DHX36/CDC42 4 GO:2000401 regulation of lymphocyte migration 4/742 61/18722 0.222212956241213 0.460458055298486 APP/MIA3/DOCK8/RHOA 4 GO:0009566 fertilization 10/742 190/18722 0.222691070576042 0.461061981829692 CD46/ALDOA/SPESP1/NR2F2/FOLR1/ASH1L/KDM5B/HEXB/VDAC2/CCT3 10 GO:0051216 cartilage development 10/742 190/18722 0.222691070576042 0.461061981829692 EFEMP1/GLG1/TRIP11/SERPINH1/BMP7/POR/ESRRA/GLI3/LTBP3/CREB3L2 10 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 8/742 146/18722 0.223214168749398 0.461951400763313 ADGRG1/LGR5/LGR4/ATP2B4/ADRB1/AKAP13/GNAQ/ADM 8 GO:0002706 regulation of lymphocyte mediated immunity 9/742 168/18722 0.223405283885769 0.462153309210929 CD46/CADM1/TFRC/CD81/CD55/LAMP1/RIF1/GATA3/SERPINB9 9 GO:0019395 fatty acid oxidation 6/742 103/18722 0.224400207569579 0.463435211285 SLC27A2/POR/CROT/ACADVL/HADHA/ETFA 6 GO:0030593 neutrophil chemotaxis 6/742 103/18722 0.224400207569579 0.463435211285 CSF3R/BSG/DPP4/JAM3/S100A9/PPIA 6 GO:0032637 interleukin-8 production 6/742 103/18722 0.224400207569579 0.463435211285 TMSB4X/HSPA1A/ANXA1/HSPA1B/DDIT3/ANXA4 6 GO:0046425 regulation of receptor signaling pathway via JAK-STAT 6/742 103/18722 0.224400207569579 0.463435211285 CAV1/CSH1/PRLR/IL10RB/LEPROT/HES1 6 GO:0043583 ear development 11/742 213/18722 0.225739990710539 0.46600733560805 LGR5/TRIP11/NAGLU/GLI3/LRP10/NIPBL/TRIOBP/IFT27/ATP6V1B1/GATA3/HES1 11 GO:0098813 nuclear chromosome segregation 14/742 281/18722 0.226525472994725 0.467433515703401 DYNC1H1/DUSP1/ATRX/TPR/NIPBL/KPNB1/RAN/CDC42/NEK6/RAB11A/ANAPC11/UBE2C/LCMT1/CCNE1 14 GO:0019693 ribose phosphate metabolic process 19/742 396/18722 0.2270178583418 0.468253954158035 GAPDH/SLC26A2/APP/LDHA/ALDOA/ACSS1/TPST2/TMSB4X/TPI1/CROT/ENO1/DLG1/NCOR1/NME3/PKM/PARP1/RAN/RHOA/PYGL 19 GO:0071621 granulocyte chemotaxis 7/742 125/18722 0.227483456139455 0.469018478017073 CSF3R/BSG/DPP4/JAM3/ANXA1/S100A9/PPIA 7 GO:0000209 protein polyubiquitination 12/742 236/18722 0.227908772598255 0.469272906789789 NHLRC3/TTC3/TRIM44/HECTD1/PPIA/KLHL42/HUWE1/SKP1/DDA1/ANAPC11/UBE2L3/UBE2C 12 GO:0018394 peptidyl-lysine acetylation 9/742 169/18722 0.228381692413586 0.469272906789789 SOX4/ISL1/POR/NCOA3/BRD7/GATA3/USP22/PHF20/MORF4L2 9 GO:0032731 positive regulation of interleukin-1 beta production 4/742 62/18722 0.230728002459419 0.469272906789789 APP/EGR1/ISL1/HSPB1 4 GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 4/742 62/18722 0.230728002459419 0.469272906789789 LRP1/BMP7/CSNK2B/SDCBP 4 GO:0046634 regulation of alpha-beta T cell activation 6/742 104/18722 0.230857499526178 0.469272906789789 CD81/ANXA1/GLI3/CD55/GATA3/RHOA 6 GO:0001819 positive regulation of cytokine production 22/742 467/18722 0.230907549608719 0.469272906789789 GAPDH/CD46/LRP1/APP/CADM1/MIF/IL6ST/EGR1/ISL1/FERMT1/SPTBN1/HSPA1A/CD81/ANXA1/ATP6AP2/HSPA1B/CD55/FOXP1/DHX36/DDIT3/GATA3/HSPB1 22 GO:0019439 aromatic compound catabolic process 22/742 467/18722 0.230907549608719 0.469272906789789 KCNQ1OT1/FUS/ZFP36L1/NPM1/TNRC6A/HSPA1A/UPF2/TNRC6B/YBX1/HSPA1B/ROCK1/PUM1/TET2/PON2/DHX36/CELF1/LARP1/CIRBP/DDX5/HNRNPC/SSB/BLVRA 22 GO:0002363 alpha-beta T cell lineage commitment 2/742 23/18722 0.230999446955841 0.469272906789789 CTSL/RHOA 2 GO:0006929 substrate-dependent cell migration 2/742 23/18722 0.230999446955841 0.469272906789789 NRP1/SDCBP 2 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 2/742 23/18722 0.230999446955841 0.469272906789789 LRP1/PTPN12 2 GO:0010888 negative regulation of lipid storage 2/742 23/18722 0.230999446955841 0.469272906789789 ITGAV/NFKBIA 2 GO:0016973 poly(A)+ mRNA export from nucleus 2/742 23/18722 0.230999446955841 0.469272906789789 PABPN1/THOC2 2 GO:0019430 removal of superoxide radicals 2/742 23/18722 0.230999446955841 0.469272906789789 SOD3/BMP7 2 GO:0021884 forebrain neuron development 2/742 23/18722 0.230999446955841 0.469272906789789 NRP2/NRP1 2 GO:0030539 male genitalia development 2/742 23/18722 0.230999446955841 0.469272906789789 LGR4/DHCR24 2 GO:0031338 regulation of vesicle fusion 2/742 23/18722 0.230999446955841 0.469272906789789 ANXA1/KIF5B 2 GO:0035162 embryonic hemopoiesis 2/742 23/18722 0.230999446955841 0.469272906789789 PBX1/GATA3 2 GO:0036303 lymph vessel morphogenesis 2/742 23/18722 0.230999446955841 0.469272906789789 SVEP1/PTPN14 2 GO:0045662 negative regulation of myoblast differentiation 2/742 23/18722 0.230999446955841 0.469272906789789 DDIT3/MBNL3 2 GO:0045980 negative regulation of nucleotide metabolic process 2/742 23/18722 0.230999446955841 0.469272906789789 NCOR1/PARP1 2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process 2/742 23/18722 0.230999446955841 0.469272906789789 CHPF/B3GAT3 2 GO:0051131 chaperone-mediated protein complex assembly 2/742 23/18722 0.230999446955841 0.469272906789789 HSPA1A/PTGES3 2 GO:0051457 maintenance of protein location in nucleus 2/742 23/18722 0.230999446955841 0.469272906789789 TXN/SKP1 2 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization 2/742 23/18722 0.230999446955841 0.469272906789789 AKAP9/GJA5 2 GO:0060353 regulation of cell adhesion molecule production 2/742 23/18722 0.230999446955841 0.469272906789789 CAV1/COLEC12 2 GO:0060384 innervation 2/742 23/18722 0.230999446955841 0.469272906789789 NRP1/ISL1 2 GO:0060396 growth hormone receptor signaling pathway 2/742 23/18722 0.230999446955841 0.469272906789789 CSH1/LEPROT 2 GO:0140112 extracellular vesicle biogenesis 2/742 23/18722 0.230999446955841 0.469272906789789 RAB11A/SDCBP 2 GO:2000810 regulation of bicellular tight junction assembly 2/742 23/18722 0.230999446955841 0.469272906789789 GJA1/ROCK1 2 GO:0010591 regulation of lamellipodium assembly 3/742 42/18722 0.231501634381926 0.469272906789789 WASF2/CDC42/CAPZB 3 GO:0016601 Rac protein signal transduction 3/742 42/18722 0.231501634381926 0.469272906789789 HACD3/WASF2/DYNLT1 3 GO:0021879 forebrain neuron differentiation 3/742 42/18722 0.231501634381926 0.469272906789789 NRP2/NRP1/HES1 3 GO:0030808 regulation of nucleotide biosynthetic process 3/742 42/18722 0.231501634381926 0.469272906789789 TMSB4X/ENO1/PARP1 3 GO:0032467 positive regulation of cytokinesis 3/742 42/18722 0.231501634381926 0.469272906789789 PKN2/CDC42/RHOA 3 GO:0033574 response to testosterone 3/742 42/18722 0.231501634381926 0.469272906789789 DUSP1/CALR/CSNK2B 3 GO:0051452 intracellular pH reduction 3/742 42/18722 0.231501634381926 0.469272906789789 GRN/ATP6AP2/CLN3 3 GO:0060999 positive regulation of dendritic spine development 3/742 42/18722 0.231501634381926 0.469272906789789 DLG5/PPP1R9A/DHX36 3 GO:1900274 regulation of phospholipase C activity 3/742 42/18722 0.231501634381926 0.469272906789789 EGFR/FLT1/GNAQ 3 GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle 3/742 42/18722 0.231501634381926 0.469272906789789 DUSP1/TPR/LCMT1 3 GO:2000404 regulation of T cell migration 3/742 42/18722 0.231501634381926 0.469272906789789 APP/DOCK8/RHOA 3 GO:2001222 regulation of neuron migration 3/742 42/18722 0.231501634381926 0.469272906789789 ADGRG1/SEMA6A/NIPBL 3 GO:0046785 microtubule polymerization 5/742 83/18722 0.232523494706089 0.470957795755671 AKAP9/MET/CLIP1/HSPA1A/HSPA1B 5 GO:0051899 membrane depolarization 5/742 83/18722 0.232523494706089 0.470957795755671 JUN/CAV1/ANK3/GJA5/PARP1 5 GO:0044839 cell cycle G2/M phase transition 8/742 148/18722 0.233968671878031 0.473302718704943 APP/PBX1/NPM1/BRD4/CALM1/RAB11A/CALM2/LCMT1 8 GO:0050905 neuromuscular process 8/742 148/18722 0.233968671878031 0.473302718704943 APP/GAA/MYCBP2/GSTO1/IGDCC3/TMEM150C/CLN3/HEXB 8 GO:2001056 positive regulation of cysteine-type endopeptidase activity 8/742 148/18722 0.233968671878031 0.473302718704943 CTSD/ARL6IP5/ASPH/LGMN/S100A9/PMAIP1/BCAP31/RHOA 8 GO:0046700 heterocycle catabolic process 21/742 445/18722 0.234955425722283 0.475104299250134 KCNQ1OT1/FUS/ZFP36L1/NPM1/TNRC6A/HSPA1A/UPF2/TNRC6B/YBX1/HSPA1B/ROCK1/PUM1/TET2/DHX36/CELF1/LARP1/CIRBP/DDX5/HNRNPC/SSB/BLVRA 21 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 10/742 193/18722 0.23677806924293 0.478593969746347 IQGAP1/MIF/IL6ST/CSH1/NRP1/ISL1/CD81/ERBB3/HES1/IGF2 10 GO:0040029 regulation of gene expression, epigenetic 6/742 105/18722 0.237372757735006 0.479403688966038 MPHOSPH8/TPR/SERTAD1/ARID1A/GPX1/IGF2 6 GO:0062207 regulation of pattern recognition receptor signaling pathway 6/742 105/18722 0.237372757735006 0.479403688966038 CAV1/LGR4/RTN4/HSPA1A/HSPA1B/PUM1 6 GO:0051224 negative regulation of protein transport 7/742 127/18722 0.239268131494648 0.482945790630587 LMAN1/ERP29/FERMT1/FRMD4A/ANXA1/OS9/TXN 7 GO:2000756 regulation of peptidyl-lysine acetylation 4/742 63/18722 0.239322124587789 0.482945790630587 SOX4/ISL1/BRD7/GATA3 4 GO:0022404 molting cycle process 5/742 84/18722 0.239896842469609 0.483513015830219 EGFR/LAMA5/LGR5/LGR4/FERMT1 5 GO:0022405 hair cycle process 5/742 84/18722 0.239896842469609 0.483513015830219 EGFR/LAMA5/LGR5/LGR4/FERMT1 5 GO:1900542 regulation of purine nucleotide metabolic process 5/742 84/18722 0.239896842469609 0.483513015830219 APP/TMSB4X/ENO1/NCOR1/PARP1 5 GO:0072593 reactive oxygen species metabolic process 12/742 239/18722 0.240638563492586 0.484810156465487 EGFR/SOD3/BMP7/GPX3/PMAIP1/SLC5A3/PRDX6/VDAC1/GPX1/PRDX4/RHOA/HBA2 12 GO:0002285 lymphocyte activation involved in immune response 10/742 194/18722 0.241545738964987 0.485465727390835 CD46/RPS6/TFRC/CD81/ANXA1/FOXP1/LAMP1/RIF1/EIF2AK4/GATA3 10 GO:0001504 neurotransmitter uptake 3/742 43/18722 0.242143229208708 0.485465727390835 ITGB1/SLC38A1/SLC6A4 3 GO:0021983 pituitary gland development 3/742 43/18722 0.242143229208708 0.485465727390835 CDH1/ISL1/HES1 3 GO:0033046 negative regulation of sister chromatid segregation 3/742 43/18722 0.242143229208708 0.485465727390835 DUSP1/TPR/LCMT1 3 GO:0033048 negative regulation of mitotic sister chromatid segregation 3/742 43/18722 0.242143229208708 0.485465727390835 DUSP1/TPR/LCMT1 3 GO:0033173 calcineurin-NFAT signaling cascade 3/742 43/18722 0.242143229208708 0.485465727390835 ATP2B4/NFAT5/SLC9A1 3 GO:0036230 granulocyte activation 3/742 43/18722 0.242143229208708 0.485465727390835 GRN/VAMP2/ANXA3 3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 3/742 43/18722 0.242143229208708 0.485465727390835 MIF/RPL26/TMEM109 3 GO:0045981 positive regulation of nucleotide metabolic process 3/742 43/18722 0.242143229208708 0.485465727390835 APP/TMSB4X/ENO1 3 GO:1900544 positive regulation of purine nucleotide metabolic process 3/742 43/18722 0.242143229208708 0.485465727390835 APP/TMSB4X/ENO1 3 GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation 3/742 43/18722 0.242143229208708 0.485465727390835 GNA12/RHOA/PDCD4 3 GO:2000816 negative regulation of mitotic sister chromatid separation 3/742 43/18722 0.242143229208708 0.485465727390835 DUSP1/TPR/LCMT1 3 GO:0001824 blastocyst development 6/742 106/18722 0.243943327570836 0.488282025202565 N4BP2L2/RPL13/RTN4/JUNB/RTF1/CITED2 6 GO:0006906 vesicle fusion 6/742 106/18722 0.243943327570836 0.488282025202565 EEA1/ANXA1/KIF5B/SYT7/VAMP2/CLN3 6 GO:0042116 macrophage activation 6/742 106/18722 0.243943327570836 0.488282025202565 GRN/APP/JUND/CTSC/MIF/FOXP1 6 GO:2000278 regulation of DNA biosynthetic process 6/742 106/18722 0.243943327570836 0.488282025202565 DUSP1/GJA1/HNRNPA1/HNRNPC/PTGES3/CCT3 6 GO:0032612 interleukin-1 production 7/742 128/18722 0.245233333120591 0.488471857594993 APP/EGR1/ISL1/ANXA1/FOXP1/HSPB1/SERPINB1 7 GO:0032652 regulation of interleukin-1 production 7/742 128/18722 0.245233333120591 0.488471857594993 APP/EGR1/ISL1/ANXA1/FOXP1/HSPB1/SERPINB1 7 GO:0001779 natural killer cell differentiation 2/742 24/18722 0.245848285175644 0.488471857594993 PBX1/HECTD1 2 GO:0001783 B cell apoptotic process 2/742 24/18722 0.245848285175644 0.488471857594993 SLC39A10/FOXP1 2 GO:0010155 regulation of proton transport 2/742 24/18722 0.245848285175644 0.488471857594993 TMSB4X/ACTN4 2 GO:0010226 response to lithium ion 2/742 24/18722 0.245848285175644 0.488471857594993 CDH1/CALR 2 GO:0030810 positive regulation of nucleotide biosynthetic process 2/742 24/18722 0.245848285175644 0.488471857594993 TMSB4X/ENO1 2 GO:0031639 plasminogen activation 2/742 24/18722 0.245848285175644 0.488471857594993 DHCR24/ENO1 2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 2/742 24/18722 0.245848285175644 0.488471857594993 GPC1/GATA3 2 GO:0051043 regulation of membrane protein ectodomain proteolysis 2/742 24/18722 0.245848285175644 0.488471857594993 ROCK1/TIMP3 2 GO:0051570 regulation of histone H3-K9 methylation 2/742 24/18722 0.245848285175644 0.488471857594993 ATRX/RIF1 2 GO:0060561 apoptotic process involved in morphogenesis 2/742 24/18722 0.245848285175644 0.488471857594993 LRP5/BMP7 2 GO:0071378 cellular response to growth hormone stimulus 2/742 24/18722 0.245848285175644 0.488471857594993 CSH1/LEPROT 2 GO:0071676 negative regulation of mononuclear cell migration 2/742 24/18722 0.245848285175644 0.488471857594993 DUSP1/MIA3 2 GO:0090343 positive regulation of cell aging 2/742 24/18722 0.245848285175644 0.488471857594993 YPEL3/HMGA1 2 GO:1900373 positive regulation of purine nucleotide biosynthetic process 2/742 24/18722 0.245848285175644 0.488471857594993 TMSB4X/ENO1 2 GO:2000209 regulation of anoikis 2/742 24/18722 0.245848285175644 0.488471857594993 ITGB1/CAV1 2 GO:2000679 positive regulation of transcription regulatory region DNA binding 2/742 24/18722 0.245848285175644 0.488471857594993 GATA3/PARP1 2 GO:0070372 regulation of ERK1 and ERK2 cascade 15/742 309/18722 0.245916904825657 0.488471857594993 EGFR/FBLN1/LRP1/APP/SEMA6A/EIF3A/DUSP1/MIF/DUSP6/ATP6AP1/NRP1/DLG1/DUSP9/TIMP3/TPBG 15 GO:0009142 nucleoside triphosphate biosynthetic process 5/742 85/18722 0.247332716127217 0.490298401953633 ALDOA/TMSB4X/ENO1/NME3/PARP1 5 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 5/742 85/18722 0.247332716127217 0.490298401953633 CAV1/IL6ST/CSH1/ISL1/HES1 5 GO:0055013 cardiac muscle cell development 5/742 85/18722 0.247332716127217 0.490298401953633 PLEC/ISL1/AKAP13/OBSL1/YY1 5 GO:0055072 iron ion homeostasis 5/742 85/18722 0.247332716127217 0.490298401953633 FTH1/TFRC/ATP6AP1/SLC40A1/EPAS1 5 GO:0098773 skin epidermis development 5/742 85/18722 0.247332716127217 0.490298401953633 EGFR/LAMA5/LGR5/LGR4/FERMT1 5 GO:0030888 regulation of B cell proliferation 4/742 64/18722 0.247989042739654 0.490811647088898 SLC39A10/TFRC/MIF/CD81 4 GO:0045670 regulation of osteoclast differentiation 4/742 64/18722 0.247989042739654 0.490811647088898 FBN1/FOS/ATP6AP1/ESRRA 4 GO:0050771 negative regulation of axonogenesis 4/742 64/18722 0.247989042739654 0.490811647088898 SEMA6A/SEMA6D/RTN4/NRP1 4 GO:1900076 regulation of cellular response to insulin stimulus 4/742 64/18722 0.247989042739654 0.490811647088898 ATP2B1/KANK1/ESRRA/IGF2 4 GO:1903131 mononuclear cell differentiation 20/742 426/18722 0.248762108690996 0.492144500173616 JUN/CD46/CTSL/ITGB1/RPS6/SOX4/PBX1/EGR1/PRKDC/ZFP36L1/ANXA1/CDK6/GLI3/HECTD1/FOXP1/GATA3/YY1/DHRS2/RHOA/TPD52 20 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 13/742 264/18722 0.249821693364975 0.493737018985107 EGFR/APP/CAV1/IQGAP1/MIF/IL6ST/CSH1/NRP1/ISL1/CD81/ERBB3/HES1/IGF2 13 GO:0043535 regulation of blood vessel endothelial cell migration 8/742 151/18722 0.250427407693547 0.493737018985107 NRP1/ATP2B4/TMSB4X/ANXA1/NF1/HSPB1/RHOA/CSNK2B 8 GO:0006275 regulation of DNA replication 6/742 107/18722 0.250566539796693 0.493737018985107 JUN/EGFR/ATRX/RBBP6/CDC42/CACYBP 6 GO:0008637 apoptotic mitochondrial changes 6/742 107/18722 0.250566539796693 0.493737018985107 JUN/HSPA1A/PMAIP1/NMT1/GPX1/VDAC2 6 GO:0042303 molting cycle 6/742 107/18722 0.250566539796693 0.493737018985107 EGFR/LAMA5/LGR5/LGR4/FERMT1/NIPBL 6 GO:0042633 hair cycle 6/742 107/18722 0.250566539796693 0.493737018985107 EGFR/LAMA5/LGR5/LGR4/FERMT1/NIPBL 6 GO:0051341 regulation of oxidoreductase activity 6/742 107/18722 0.250566539796693 0.493737018985107 EGFR/CAV1/ATP2B4/POR/CALM1/HM13 6 GO:0071868 cellular response to monoamine stimulus 6/742 107/18722 0.250566539796693 0.493737018985107 APP/ATP2B4/SLC9A1/NCSTN/ID1/TGM2 6 GO:0071870 cellular response to catecholamine stimulus 6/742 107/18722 0.250566539796693 0.493737018985107 APP/ATP2B4/SLC9A1/NCSTN/ID1/TGM2 6 GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 6/742 107/18722 0.250566539796693 0.493737018985107 CAV1/HSPA1A/HSPA1B/HECTD1/BCAP31/DDA1 6 GO:0007093 mitotic cell cycle checkpoint signaling 7/742 129/18722 0.251244510967151 0.494875551904995 DUSP1/SOX4/RPL26/PRKDC/PPP1R10/TPR/LCMT1 7 GO:0071805 potassium ion transmembrane transport 11/742 219/18722 0.252752710243965 0.496675994934307 AKAP9/ITGB1/KCNN4/SLC12A9/CAV1/ANK3/SLC9A1/DLG1/ATP1A1/VAMP2/YWHAE 11 GO:0006775 fat-soluble vitamin metabolic process 3/742 44/18722 0.252862373939227 0.496675994934307 LRP2/LGMN/CYP11A1 3 GO:0008542 visual learning 3/742 44/18722 0.252862373939227 0.496675994934307 APP/ITGB1/NF1 3 GO:0031295 T cell costimulation 3/742 44/18722 0.252862373939227 0.496675994934307 CAV1/DPP4/CD81 3 GO:0042269 regulation of natural killer cell mediated cytotoxicity 3/742 44/18722 0.252862373939227 0.496675994934307 CADM1/LAMP1/SERPINB9 3 GO:0060324 face development 3/742 44/18722 0.252862373939227 0.496675994934307 ANKRD11/NIPBL/ARID5B 3 GO:0150076 neuroinflammatory response 3/742 44/18722 0.252862373939227 0.496675994934307 GRN/ITGB1/CTSC 3 GO:0007584 response to nutrient 9/742 174/18722 0.253853884780578 0.498425354060435 EGFR/ATP2B1/LDHA/SLC6A4/AGL/BMP7/POR/FOLR1/SLC16A1 9 GO:0006140 regulation of nucleotide metabolic process 5/742 86/18722 0.25482722079969 0.499740560043855 APP/TMSB4X/ENO1/NCOR1/PARP1 5 GO:0015908 fatty acid transport 5/742 86/18722 0.25482722079969 0.499740560043855 SLC2A1/SLC27A2/ANXA1/CROT/PLIN2 5 GO:2000117 negative regulation of cysteine-type endopeptidase activity 5/742 86/18722 0.25482722079969 0.499740560043855 DHCR24/POR/GPX1/SIAH2/SERPINB9 5 GO:0016125 sterol metabolic process 8/742 152/18722 0.255994883756248 0.501831240379312 APP/DHCR24/LRP5/POR/MBTPS1/ACADVL/CYP11A1/CYP19A1 8 GO:0002720 positive regulation of cytokine production involved in immune response 4/742 65/18722 0.25672253120064 0.502062274002835 CD81/CD55/DHX36/GATA3 4 GO:0015909 long-chain fatty acid transport 4/742 65/18722 0.25672253120064 0.502062274002835 SLC2A1/SLC27A2/ANXA1/PLIN2 4 GO:0033692 cellular polysaccharide biosynthetic process 4/742 65/18722 0.25672253120064 0.502062274002835 AGL/PTGES3/IGF2/UGP2 4 GO:0038034 signal transduction in absence of ligand 4/742 65/18722 0.25672253120064 0.502062274002835 ITGAV/HSPA1A/HSPA1B/ERBB3 4 GO:0070613 regulation of protein processing 4/742 65/18722 0.25672253120064 0.502062274002835 GLG1/TMEM59/ENO1/CLN3 4 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 4/742 65/18722 0.25672253120064 0.502062274002835 ITGAV/HSPA1A/HSPA1B/ERBB3 4 GO:0034440 lipid oxidation 6/742 108/18722 0.257239713980654 0.502476942295148 SLC27A2/POR/CROT/ACADVL/HADHA/ETFA 6 GO:0098659 inorganic cation import across plasma membrane 6/742 108/18722 0.257239713980654 0.502476942295148 SLC39A10/SLC12A9/ATP2B4/SLC9A1/DLG1/ATP1A1 6 GO:0099587 inorganic ion import across plasma membrane 6/742 108/18722 0.257239713980654 0.502476942295148 SLC39A10/SLC12A9/ATP2B4/SLC9A1/DLG1/ATP1A1 6 GO:0070588 calcium ion transmembrane transport 15/742 312/18722 0.25742019588859 0.502630738217248 AHNAK/ATP2B1/ITGAV/C4orf3/GSTO1/ATP2B4/SLC9A1/DIAPH1/TMEM165/SEC61A1/DDIT3/CALM1/VDAC1/CALM2/YWHAE 15 GO:0003094 glomerular filtration 2/742 25/18722 0.260729510514856 0.505297678283008 GJA1/GJA5 2 GO:0006658 phosphatidylserine metabolic process 2/742 25/18722 0.260729510514856 0.505297678283008 SERINC1/SERINC3 2 GO:0010560 positive regulation of glycoprotein biosynthetic process 2/742 25/18722 0.260729510514856 0.505297678283008 NCSTN/TCF7L2 2 GO:0021846 cell proliferation in forebrain 2/742 25/18722 0.260729510514856 0.505297678283008 GLI3/PCM1 2 GO:0032331 negative regulation of chondrocyte differentiation 2/742 25/18722 0.260729510514856 0.505297678283008 EFEMP1/LTBP3 2 GO:0045109 intermediate filament organization 2/742 25/18722 0.260729510514856 0.505297678283008 PLEC/DSP 2 GO:0048596 embryonic camera-type eye morphogenesis 2/742 25/18722 0.260729510514856 0.505297678283008 BMP7/CITED2 2 GO:0051450 myoblast proliferation 2/742 25/18722 0.260729510514856 0.505297678283008 MALAT1/GPX1 2 GO:0062009 secondary palate development 2/742 25/18722 0.260729510514856 0.505297678283008 TGFBR3/DLG1 2 GO:0070199 establishment of protein localization to chromosome 2/742 25/18722 0.260729510514856 0.505297678283008 NIPBL/CCT3 2 GO:0071450 cellular response to oxygen radical 2/742 25/18722 0.260729510514856 0.505297678283008 SOD3/BMP7 2 GO:0071451 cellular response to superoxide 2/742 25/18722 0.260729510514856 0.505297678283008 SOD3/BMP7 2 GO:0072207 metanephric epithelium development 2/742 25/18722 0.260729510514856 0.505297678283008 LGR4/HES1 2 GO:0086013 membrane repolarization during cardiac muscle cell action potential 2/742 25/18722 0.260729510514856 0.505297678283008 ATP1A1/YWHAE 2 GO:0090382 phagosome maturation 2/742 25/18722 0.260729510514856 0.505297678283008 SYT7/CLN3 2 GO:1900078 positive regulation of cellular response to insulin stimulus 2/742 25/18722 0.260729510514856 0.505297678283008 ESRRA/IGF2 2 GO:1904385 cellular response to angiotensin 2/742 25/18722 0.260729510514856 0.505297678283008 CAV1/ROCK1 2 GO:1904753 negative regulation of vascular associated smooth muscle cell migration 2/742 25/18722 0.260729510514856 0.505297678283008 GNA12/RHOA 2 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell 2/742 25/18722 0.260729510514856 0.505297678283008 NFAT5/RHOA 2 GO:0120254 olefinic compound metabolic process 8/742 153/18722 0.261600450192384 0.506786754490343 EGR1/ADM/GPX1/PTGES3/CYP11A1/CYP2J2/GPX4/HSD17B1 8 GO:0019646 aerobic electron transport chain 5/742 87/18722 0.262376467187094 0.507692811556695 COX6A1/NDUFB9/UQCRH/COX8C/COX5A 5 GO:0044070 regulation of anion transport 5/742 87/18722 0.262376467187094 0.507692811556695 TCAF1/ITGB1/SLC43A2/GABRE/ARL6IP5 5 GO:1901879 regulation of protein depolymerization 5/742 87/18722 0.262376467187094 0.507692811556695 SPTAN1/SPTBN1/TRIOBP/DSTN/CAPZB 5 GO:1904950 negative regulation of establishment of protein localization 7/742 131/18722 0.263396913484269 0.508360423487073 LMAN1/ERP29/FERMT1/FRMD4A/ANXA1/OS9/TXN 7 GO:0034655 nucleobase-containing compound catabolic process 19/742 407/18722 0.263533142375539 0.508360423487073 KCNQ1OT1/FUS/ZFP36L1/NPM1/TNRC6A/HSPA1A/UPF2/TNRC6B/YBX1/HSPA1B/ROCK1/PUM1/DHX36/CELF1/LARP1/CIRBP/DDX5/HNRNPC/SSB 19 GO:0003197 endocardial cushion development 3/742 45/18722 0.263647652828721 0.508360423487073 BMP7/ISL1/CITED2 3 GO:0003254 regulation of membrane depolarization 3/742 45/18722 0.263647652828721 0.508360423487073 ANK3/GJA5/PARP1 3 GO:0051985 negative regulation of chromosome segregation 3/742 45/18722 0.263647652828721 0.508360423487073 DUSP1/TPR/LCMT1 3 GO:0085029 extracellular matrix assembly 3/742 45/18722 0.263647652828721 0.508360423487073 LAMB1/DAG1/LTBP3 3 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process 3/742 45/18722 0.263647652828721 0.508360423487073 HSPA1A/NMT1/VDAC2 3 GO:1905819 negative regulation of chromosome separation 3/742 45/18722 0.263647652828721 0.508360423487073 DUSP1/TPR/LCMT1 3 GO:2000273 positive regulation of signaling receptor activity 3/742 45/18722 0.263647652828721 0.508360423487073 ITGB1/NRP1/NCOA3 3 GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 4/742 66/18722 0.265516428226756 0.510966558410665 TFRC/PRKDC/RIF1/YY1 4 GO:0016444 somatic cell DNA recombination 4/742 66/18722 0.265516428226756 0.510966558410665 TFRC/PRKDC/RIF1/YY1 4 GO:0050918 positive chemotaxis 4/742 66/18722 0.265516428226756 0.510966558410665 LRP1/MET/MIF/NRP1 4 GO:0072678 T cell migration 4/742 66/18722 0.265516428226756 0.510966558410665 APP/PLEC/DOCK8/RHOA 4 GO:1902476 chloride transmembrane transport 4/742 66/18722 0.265516428226756 0.510966558410665 SLC26A2/SLC12A9/GABRE/PCYOX1 4 GO:0016236 macroautophagy 14/742 291/18722 0.26604456779773 0.511783553318062 GAPDH/UFL1/VPS13C/LAMP2/RB1CC1/LARP1/ATP6V1B1/CALM1/HUWE1/VDAC1/TEX264/ATP6V0B/CLN3/UFC1 14 GO:0070663 regulation of leukocyte proliferation 12/742 245/18722 0.266869108952513 0.51316987085458 CD46/SLC39A10/TFRC/MIF/IL6ST/DLG5/CD81/ANXA1/DLG1/CD55/HES1/IGF2 12 GO:0050770 regulation of axonogenesis 8/742 154/18722 0.2672425748413 0.513688062146312 LRP1/GOLGA4/SEMA6A/MACF1/SEMA6D/RTN4/NRP1/RAB11A 8 GO:0009259 ribonucleotide metabolic process 18/742 385/18722 0.268638488533034 0.516170413595172 GAPDH/SLC26A2/APP/LDHA/ALDOA/ACSS1/TPST2/TMSB4X/TPI1/CROT/ENO1/DLG1/NCOR1/NME3/PKM/PARP1/RAN/RHOA 18 GO:0007260 tyrosine phosphorylation of STAT protein 5/742 88/18722 0.269976576988401 0.518338239534668 CAV1/IL6ST/CSH1/ISL1/HES1 5 GO:0031110 regulation of microtubule polymerization or depolymerization 5/742 88/18722 0.269976576988401 0.518338239534668 AKAP9/MET/CLIP1/HSPA1A/HSPA1B 5 GO:0002698 negative regulation of immune effector process 6/742 110/18722 0.270725190421454 0.51876743238246 CD46/GRN/PRKDC/ANXA1/CD55/SERPINB9 6 GO:0006939 smooth muscle contraction 6/742 110/18722 0.270725190421454 0.51876743238246 ATP2B1/CAV1/ATP2B4/DLG1/ROCK1/RHOA 6 GO:0032611 interleukin-1 beta production 6/742 110/18722 0.270725190421454 0.51876743238246 APP/EGR1/ISL1/FOXP1/HSPB1/SERPINB1 6 GO:0032651 regulation of interleukin-1 beta production 6/742 110/18722 0.270725190421454 0.51876743238246 APP/EGR1/ISL1/FOXP1/HSPB1/SERPINB1 6 GO:0090174 organelle membrane fusion 6/742 110/18722 0.270725190421454 0.51876743238246 EEA1/ANXA1/KIF5B/SYT7/VAMP2/CLN3 6 GO:0043414 macromolecule methylation 15/742 316/18722 0.273059929175136 0.521266963558457 FOS/ZC3H13/ATRX/MPHOSPH8/BRD4/KMT2C/BTG1/ASH1L/TET2/NSD1/RIF1/RTF1/GATA3/PARP1/LCMT1 15 GO:0006879 cellular iron ion homeostasis 4/742 67/18722 0.274364645146901 0.521266963558457 FTH1/TFRC/ATP6AP1/SLC40A1 4 GO:0009880 embryonic pattern specification 4/742 67/18722 0.274364645146901 0.521266963558457 NRP2/NRP1/BMP7/PGAP1 4 GO:0016445 somatic diversification of immunoglobulins 4/742 67/18722 0.274364645146901 0.521266963558457 TFRC/PRKDC/RIF1/YY1 4 GO:0048814 regulation of dendrite morphogenesis 4/742 67/18722 0.274364645146901 0.521266963558457 CUX1/DHX36/OBSL1/ID1 4 GO:0050435 amyloid-beta metabolic process 4/742 67/18722 0.274364645146901 0.521266963558457 RTN4/MME/NCSTN/ROCK1 4 GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 4/742 67/18722 0.274364645146901 0.521266963558457 CD81/ANXA1/CD55/GATA3 4 GO:0001974 blood vessel remodeling 3/742 46/18722 0.27448797872687 0.521266963558457 CST3/EPAS1/TGM2 3 GO:0031294 lymphocyte costimulation 3/742 46/18722 0.27448797872687 0.521266963558457 CAV1/DPP4/CD81 3 GO:0033047 regulation of mitotic sister chromatid segregation 3/742 46/18722 0.27448797872687 0.521266963558457 DUSP1/TPR/LCMT1 3 GO:0043462 regulation of ATPase activity 3/742 46/18722 0.27448797872687 0.521266963558457 PFN1/DNAJB1/CNN3 3 GO:0043616 keratinocyte proliferation 3/742 46/18722 0.27448797872687 0.521266963558457 ZFP36L1/FERMT1/SRSF6 3 GO:0048701 embryonic cranial skeleton morphogenesis 3/742 46/18722 0.27448797872687 0.521266963558457 GLI3/NIPBL/SLC39A1 3 GO:0070828 heterochromatin organization 3/742 46/18722 0.27448797872687 0.521266963558457 MPHOSPH8/TPR/HP1BP3 3 GO:2000107 negative regulation of leukocyte apoptotic process 3/742 46/18722 0.27448797872687 0.521266963558457 SLC39A10/FOXP1/DOCK8 3 GO:0006109 regulation of carbohydrate metabolic process 9/742 178/18722 0.274868415660443 0.521266963558457 APP/DDB1/PMAIP1/RANBP2/NCOR1/SLC35B4/CLTC/IGF2/LCMT1 9 GO:0001573 ganglioside metabolic process 2/742 26/18722 0.275617268990828 0.521266963558457 HEXA/HEXB 2 GO:0006517 protein deglycosylation 2/742 26/18722 0.275617268990828 0.521266963558457 MAN2A1/MAN1A2 2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane 2/742 26/18722 0.275617268990828 0.521266963558457 SEC61A1/SEC63 2 GO:0006760 folic acid-containing compound metabolic process 2/742 26/18722 0.275617268990828 0.521266963558457 SLC19A1/FOLR1 2 GO:0014829 vascular associated smooth muscle contraction 2/742 26/18722 0.275617268990828 0.521266963558457 ATP2B1/RHOA 2 GO:0033522 histone H2A ubiquitination 2/742 26/18722 0.275617268990828 0.521266963558457 DDB1/SKP1 2 GO:0042634 regulation of hair cycle 2/742 26/18722 0.275617268990828 0.521266963558457 FERMT1/NIPBL 2 GO:0045026 plasma membrane fusion 2/742 26/18722 0.275617268990828 0.521266963558457 SPESP1/FOLR1 2 GO:0045672 positive regulation of osteoclast differentiation 2/742 26/18722 0.275617268990828 0.521266963558457 FOS/ATP6AP1 2 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity 2/742 26/18722 0.275617268990828 0.521266963558457 CADM1/LAMP1 2 GO:0046639 negative regulation of alpha-beta T cell differentiation 2/742 26/18722 0.275617268990828 0.521266963558457 ANXA1/GLI3 2 GO:0048668 collateral sprouting 2/742 26/18722 0.275617268990828 0.521266963558457 LRP1/APP 2 GO:0051016 barbed-end actin filament capping 2/742 26/18722 0.275617268990828 0.521266963558457 TRIOBP/CAPZB 2 GO:0051350 negative regulation of lyase activity 2/742 26/18722 0.275617268990828 0.521266963558457 AKAP9/PHPT1 2 GO:0051560 mitochondrial calcium ion homeostasis 2/742 26/18722 0.275617268990828 0.521266963558457 BCAP31/TGM2 2 GO:0072273 metanephric nephron morphogenesis 2/742 26/18722 0.275617268990828 0.521266963558457 LGR4/HES1 2 GO:0097205 renal filtration 2/742 26/18722 0.275617268990828 0.521266963558457 GJA1/GJA5 2 GO:0099637 neurotransmitter receptor transport 2/742 26/18722 0.275617268990828 0.521266963558457 VAMP2/RAB11A 2 GO:0071867 response to monoamine 6/742 111/18722 0.277532105379659 0.524427755632101 APP/ATP2B4/SLC9A1/NCSTN/ID1/TGM2 6 GO:0071869 response to catecholamine 6/742 111/18722 0.277532105379659 0.524427755632101 APP/ATP2B4/SLC9A1/NCSTN/ID1/TGM2 6 GO:0032259 methylation 17/742 364/18722 0.277607000197964 0.524427755632101 FOS/ZC3H13/ATRX/MPHOSPH8/BRD4/KMT2C/METTL7A/BTG1/ASH1L/MTR/TET2/NSD1/RIF1/RTF1/GATA3/PARP1/LCMT1 17 GO:0046631 alpha-beta T cell activation 8/742 156/18722 0.278630324102094 0.526159709886982 CTSL/CD81/ANXA1/GLI3/CD55/FOXP1/GATA3/RHOA 8 GO:0007626 locomotory behavior 9/742 179/18722 0.280200315695736 0.528922261955268 APP/GAA/EGR1/DPP4/ZFHX3/NAGLU/PUM1/NCOR1/HEXB 9 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 4/742 68/18722 0.283261174789928 0.533680474241893 IL6ST/CSH1/ISL1/HES1 4 GO:0046637 regulation of alpha-beta T cell differentiation 4/742 68/18722 0.283261174789928 0.533680474241893 ANXA1/GLI3/GATA3/RHOA 4 GO:0051148 negative regulation of muscle cell differentiation 4/742 68/18722 0.283261174789928 0.533680474241893 YBX1/YY1/IGF2/PDCD4 4 GO:1901607 alpha-amino acid biosynthetic process 4/742 68/18722 0.283261174789928 0.533680474241893 ATP2B4/MTR/SERINC3/CLN3 4 GO:1904888 cranial skeletal system development 4/742 68/18722 0.283261174789928 0.533680474241893 GLI3/NIPBL/SLC39A1/TMEM107 4 GO:0043406 positive regulation of MAP kinase activity 6/742 112/18722 0.284378213910245 0.534802981093255 EGFR/ERP29/IQGAP1/FLT1/MAGED1/AKAP13 6 GO:0046632 alpha-beta T cell differentiation 6/742 112/18722 0.284378213910245 0.534802981093255 CTSL/ANXA1/GLI3/FOXP1/GATA3/RHOA 6 GO:1901988 negative regulation of cell cycle phase transition 12/742 249/18722 0.284866373840713 0.534802981093255 DUSP1/SOX4/RPL26/PRKDC/ZFP36L1/PPP1R10/TPR/DLG1/CTDSPL/EIF2AK4/BRD7/LCMT1 12 GO:0097581 lamellipodium organization 5/742 90/18722 0.285313959503117 0.534802981093255 ITGB1/KANK1/WASF2/CDC42/CAPZB 5 GO:0001774 microglial cell activation 3/742 47/18722 0.285372602866765 0.534802981093255 GRN/APP/CTSC 3 GO:0010712 regulation of collagen metabolic process 3/742 47/18722 0.285372602866765 0.534802981093255 ITGB1/SUCO/CST3 3 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 3/742 47/18722 0.285372602866765 0.534802981093255 HSPA1A/HSPA1B/SPPL2B 3 GO:0031641 regulation of myelination 3/742 47/18722 0.285372602866765 0.534802981093255 DAG1/CTSC/DLG1 3 GO:0045601 regulation of endothelial cell differentiation 3/742 47/18722 0.285372602866765 0.534802981093255 BTG1/ROCK1/ID1 3 GO:0045747 positive regulation of Notch signaling pathway 3/742 47/18722 0.285372602866765 0.534802981093255 AAK1/IL6ST/HES1 3 GO:0047496 vesicle transport along microtubule 3/742 47/18722 0.285372602866765 0.534802981093255 DYNC1H1/KIF5B/CLN3 3 GO:0061001 regulation of dendritic spine morphogenesis 3/742 47/18722 0.285372602866765 0.534802981093255 PPP1R9A/CFL1/DHX36 3 GO:0097300 programmed necrotic cell death 3/742 47/18722 0.285372602866765 0.534802981093255 CAV1/ASAH1/PYGL 3 GO:0120163 negative regulation of cold-induced thermogenesis 3/742 47/18722 0.285372602866765 0.534802981093255 LGR4/DDIT3/ID1 3 GO:0002687 positive regulation of leukocyte migration 7/742 135/18722 0.288166195992684 0.53962888862921 APP/JAM3/CALR/MIA3/LGMN/DOCK8/RHOA 7 GO:0042157 lipoprotein metabolic process 7/742 135/18722 0.288166195992684 0.53962888862921 LRP1/ITGAV/CTSD/GPAA1/PGAP1/NMT1/NOTUM 7 GO:0018393 internal peptidyl-lysine acetylation 8/742 158/18722 0.290145709182561 0.540493121328317 ISL1/POR/NCOA3/BRD7/GATA3/USP22/PHF20/MORF4L2 8 GO:0003171 atrioventricular valve development 2/742 27/18722 0.290487699823215 0.540493121328317 SOX4/GJA5 2 GO:0007263 nitric oxide mediated signal transduction 2/742 27/18722 0.290487699823215 0.540493121328317 EGFR/ATP2B4 2 GO:0008053 mitochondrial fusion 2/742 27/18722 0.290487699823215 0.540493121328317 TFRC/HUWE1 2 GO:0009651 response to salt stress 2/742 27/18722 0.290487699823215 0.540493121328317 ZFP36L1/EFHD1 2 GO:0010561 negative regulation of glycoprotein biosynthetic process 2/742 27/18722 0.290487699823215 0.540493121328317 ITM2B/TMEM59 2 GO:0010586 miRNA metabolic process 2/742 27/18722 0.290487699823215 0.540493121328317 KCNQ1OT1/DDX17 2 GO:0015813 L-glutamate transmembrane transport 2/742 27/18722 0.290487699823215 0.540493121328317 ITGB1/ARL6IP5 2 GO:0032781 positive regulation of ATPase activity 2/742 27/18722 0.290487699823215 0.540493121328317 PFN1/DNAJB1 2 GO:0035235 ionotropic glutamate receptor signaling pathway 2/742 27/18722 0.290487699823215 0.540493121328317 APP/CLN3 2 GO:0045830 positive regulation of isotype switching 2/742 27/18722 0.290487699823215 0.540493121328317 TFRC/RIF1 2 GO:0051953 negative regulation of amine transport 2/742 27/18722 0.290487699823215 0.540493121328317 SLC43A2/ARL6IP5 2 GO:0099625 ventricular cardiac muscle cell membrane repolarization 2/742 27/18722 0.290487699823215 0.540493121328317 AKAP9/GJA5 2 GO:1902883 negative regulation of response to oxidative stress 2/742 27/18722 0.290487699823215 0.540493121328317 MET/TXN 2 GO:1902914 regulation of protein polyubiquitination 2/742 27/18722 0.290487699823215 0.540493121328317 TRIM44/PPIA 2 GO:1903205 regulation of hydrogen peroxide-induced cell death 2/742 27/18722 0.290487699823215 0.540493121328317 MET/TXN 2 GO:1903319 positive regulation of protein maturation 2/742 27/18722 0.290487699823215 0.540493121328317 SOX4/ENO1 2 GO:0006368 transcription elongation from RNA polymerase II promoter 4/742 69/18722 0.292200099257143 0.543270037760741 BRD4/SERTAD1/ARID1A/RTF1 4 GO:0060193 positive regulation of lipase activity 4/742 69/18722 0.292200099257143 0.543270037760741 EGFR/FLT1/GNAQ/RHOA 4 GO:0042147 retrograde transport, endosome to Golgi 5/742 91/18722 0.29304357610979 0.544428456555984 TMEM87A/GCC2/ERC1/CLTC/RHOBTB3 5 GO:0098661 inorganic anion transmembrane transport 5/742 91/18722 0.29304357610979 0.544428456555984 SLC26A2/SLC12A9/SLC13A4/GABRE/PCYOX1 5 GO:0043624 cellular protein complex disassembly 7/742 136/18722 0.294443607087923 0.546823841734714 SPTAN1/SPTBN1/TRIOBP/CFL1/DSTN/CAPZB/EIF5A 7 GO:0002715 regulation of natural killer cell mediated immunity 3/742 48/18722 0.296291122662022 0.548810703393471 CADM1/LAMP1/SERPINB9 3 GO:0006111 regulation of gluconeogenesis 3/742 48/18722 0.296291122662022 0.548810703393471 DDB1/RANBP2/SLC35B4 3 GO:0010569 regulation of double-strand break repair via homologous recombination 3/742 48/18722 0.296291122662022 0.548810703393471 FUS/RIF1/PARP1 3 GO:0033628 regulation of cell adhesion mediated by integrin 3/742 48/18722 0.296291122662022 0.548810703393471 DPP4/JAM3/FERMT1 3 GO:0048146 positive regulation of fibroblast proliferation 3/742 48/18722 0.296291122662022 0.548810703393471 MIF/PRKDC/CDK6 3 GO:0097720 calcineurin-mediated signaling 3/742 48/18722 0.296291122662022 0.548810703393471 ATP2B4/NFAT5/SLC9A1 3 GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 3/742 48/18722 0.296291122662022 0.548810703393471 RPL23/EIF3H/SDCBP 3 GO:0002366 leukocyte activation involved in immune response 13/742 275/18722 0.296911149857307 0.549753028596362 CD46/GRN/RPS6/TFRC/CD81/ANXA1/VAMP2/FOXP1/LAMP1/RIF1/EIF2AK4/GATA3/ANXA3 13 GO:0022904 respiratory electron transport chain 6/742 114/18722 0.298177266165343 0.551270843883531 COX6A1/PLEC/NDUFB9/UQCRH/COX8C/COX5A 6 GO:0046660 female sex differentiation 6/742 114/18722 0.298177266165343 0.551270843883531 LRP2/HSPA5/ADAMTS1/NR2F2/ARID5B/CYP19A1 6 GO:0051261 protein depolymerization 6/742 114/18722 0.298177266165343 0.551270843883531 SPTAN1/SPTBN1/TRIOBP/CFL1/DSTN/CAPZB 6 GO:1904892 regulation of receptor signaling pathway via STAT 6/742 114/18722 0.298177266165343 0.551270843883531 CAV1/CSH1/PRLR/IL10RB/LEPROT/HES1 6 GO:0000086 G2/M transition of mitotic cell cycle 7/742 137/18722 0.300751041510322 0.555304648883277 APP/PBX1/BRD4/CALM1/RAB11A/CALM2/LCMT1 7 GO:0008203 cholesterol metabolic process 7/742 137/18722 0.300751041510322 0.555304648883277 APP/DHCR24/LRP5/POR/MBTPS1/ACADVL/CYP11A1 7 GO:0045471 response to ethanol 7/742 137/18722 0.300751041510322 0.555304648883277 RPL15/EEF1B2/SDF4/TUFM/GATA3/RHOA/HPGD 7 GO:0001708 cell fate specification 5/742 92/18722 0.300808753119767 0.555304648883277 ITGB1/NRP1/LMO4/ISL1/GLI3 5 GO:0002548 monocyte chemotaxis 4/742 70/18722 0.301175597061771 0.555359256993336 DUSP1/FLT1/ANXA1/LGMN 4 GO:0003407 neural retina development 4/742 70/18722 0.301175597061771 0.555359256993336 ATP2B1/NAGLU/ATP2B4/OBSL1 4 GO:0060415 muscle tissue morphogenesis 4/742 70/18722 0.301175597061771 0.555359256993336 LRP2/TGFBR3/DSP/ISL1 4 GO:0006475 internal protein amino acid acetylation 8/742 160/18722 0.301776220748515 0.556101916258215 ISL1/POR/NCOA3/BRD7/GATA3/USP22/PHF20/MORF4L2 8 GO:0002819 regulation of adaptive immune response 9/742 183/18722 0.301803489370096 0.556101916258215 CD46/TFRC/IL6ST/CD81/ANXA1/CD55/RIF1/EIF2AK4/GATA3 9 GO:0034612 response to tumor necrosis factor 12/742 253/18722 0.303217211151457 0.558498517184265 ZFP36L1/KRT8/TMSB4X/HSPA1A/ACTN4/HSPA1B/SPPL2B/ASAH1/NFKBIA/KRT18/GATA3/EIF5A 12 GO:0016197 endosomal transport 11/742 230/18722 0.304904236984345 0.558620356644942 TINAGL1/TMEM87A/EEA1/GCC2/KIAA1109/CMTM6/ERC1/CLTC/RHOBTB3/LEPROT/RAB11A 11 GO:0000303 response to superoxide 2/742 28/18722 0.305318818409179 0.558620356644942 SOD3/BMP7 2 GO:0003156 regulation of animal organ formation 2/742 28/18722 0.305318818409179 0.558620356644942 BMP7/CITED2 2 GO:0006972 hyperosmotic response 2/742 28/18722 0.305318818409179 0.558620356644942 SLC2A1/EFHD1 2 GO:0007064 mitotic sister chromatid cohesion 2/742 28/18722 0.305318818409179 0.558620356644942 ATRX/NIPBL 2 GO:0010460 positive regulation of heart rate 2/742 28/18722 0.305318818409179 0.558620356644942 ADRB1/ADM 2 GO:0010575 positive regulation of vascular endothelial growth factor production 2/742 28/18722 0.305318818409179 0.558620356644942 IL6ST/ISL1 2 GO:0019098 reproductive behavior 2/742 28/18722 0.305318818409179 0.558620356644942 APP/HEXB 2 GO:0031440 regulation of mRNA 3'-end processing 2/742 28/18722 0.305318818409179 0.558620356644942 ZFP36L1/DHX36 2 GO:0034123 positive regulation of toll-like receptor signaling pathway 2/742 28/18722 0.305318818409179 0.558620356644942 CAV1/RTN4 2 GO:0042983 amyloid precursor protein biosynthetic process 2/742 28/18722 0.305318818409179 0.558620356644942 ITM2B/NCSTN 2 GO:0042984 regulation of amyloid precursor protein biosynthetic process 2/742 28/18722 0.305318818409179 0.558620356644942 ITM2B/NCSTN 2 GO:0045686 negative regulation of glial cell differentiation 2/742 28/18722 0.305318818409179 0.558620356644942 NF1/HES1 2 GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT 2/742 28/18722 0.305318818409179 0.558620356644942 CAV1/LEPROT 2 GO:0051503 adenine nucleotide transport 2/742 28/18722 0.305318818409179 0.558620356644942 GJA1/SLC19A1 2 GO:0070076 histone lysine demethylation 2/742 28/18722 0.305318818409179 0.558620356644942 KDM5A/KDM5B 2 GO:0099623 regulation of cardiac muscle cell membrane repolarization 2/742 28/18722 0.305318818409179 0.558620356644942 AKAP9/GJA5 2 GO:1903020 positive regulation of glycoprotein metabolic process 2/742 28/18722 0.305318818409179 0.558620356644942 NCSTN/TCF7L2 2 GO:0007602 phototransduction 3/742 49/18722 0.307233487681673 0.559636220187119 NMT1/CDS1/GNAQ 3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 3/742 49/18722 0.307233487681673 0.559636220187119 BMP7/CSNK2B/SDCBP 3 GO:0014075 response to amine 3/742 49/18722 0.307233487681673 0.559636220187119 GLDC/RANBP2/CALM1 3 GO:0021695 cerebellar cortex development 3/742 49/18722 0.307233487681673 0.559636220187119 HSPA5/NAGLU/RERE 3 GO:0030225 macrophage differentiation 3/742 49/18722 0.307233487681673 0.559636220187119 APP/PARP1/CDC42 3 GO:0048168 regulation of neuronal synaptic plasticity 3/742 49/18722 0.307233487681673 0.559636220187119 APP/CLN3/RAB11A 3 GO:0050832 defense response to fungus 3/742 49/18722 0.307233487681673 0.559636220187119 GAPDH/S100A9/COTL1 3 GO:0052372 modulation by symbiont of entry into host 3/742 49/18722 0.307233487681673 0.559636220187119 ITGAV/P4HB/CAV1 3 GO:0060986 endocrine hormone secretion 3/742 49/18722 0.307233487681673 0.559636220187119 GJA1/GATA3/CGA 3 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 3/742 49/18722 0.307233487681673 0.559636220187119 PMAIP1/TIMP3/GPX1 3 GO:1990573 potassium ion import across plasma membrane 3/742 49/18722 0.307233487681673 0.559636220187119 SLC12A9/DLG1/ATP1A1 3 GO:1990928 response to amino acid starvation 3/742 49/18722 0.307233487681673 0.559636220187119 SLC38A2/EIF2AK4/LARP1 3 GO:0006163 purine nucleotide metabolic process 18/742 396/18722 0.308634783944488 0.561981508546174 GAPDH/SLC26A2/APP/LDHA/ALDOA/ACSS1/TPST2/TMSB4X/TPI1/CROT/ENO1/DLG1/NCOR1/NME3/PKM/PARP1/RAN/RHOA 18 GO:0050795 regulation of behavior 4/742 71/18722 0.310181949657345 0.564590578963627 GJA1/ZFHX3/ADRB1/EIF2AK4 4 GO:0002040 sprouting angiogenesis 9/742 185/18722 0.312752720772638 0.569060199122222 ITGB1/SEMA6A/EPHB4/NRP1/MIA3/ANXA1/PKM/CDC42/RHOA 9 GO:0021953 central nervous system neuron differentiation 8/742 162/18722 0.313509304060457 0.570226790154144 NRP2/MYCBP2/SOX4/NRP1/LMO4/ISL1/GLI3/HES1 8 GO:0030098 lymphocyte differentiation 17/742 374/18722 0.315458926431657 0.57124095292118 CD46/CTSL/ITGB1/RPS6/SOX4/PBX1/EGR1/PRKDC/ZFP36L1/ANXA1/GLI3/HECTD1/FOXP1/GATA3/YY1/RHOA/TPD52 17 GO:0032091 negative regulation of protein binding 5/742 94/18722 0.316430826189817 0.57124095292118 LRPAP1/CAV1/PTPRF/ROCK1/ID1 5 GO:0048704 embryonic skeletal system morphogenesis 5/742 94/18722 0.316430826189817 0.57124095292118 BMP7/GLI3/DLG1/NIPBL/SLC39A1 5 GO:0001961 positive regulation of cytokine-mediated signaling pathway 3/742 50/18722 0.318190003961134 0.57124095292118 HSPA1A/TRIM44/HSPA1B 3 GO:0046638 positive regulation of alpha-beta T cell differentiation 3/742 50/18722 0.318190003961134 0.57124095292118 ANXA1/GLI3/RHOA 3 GO:0050873 brown fat cell differentiation 3/742 50/18722 0.318190003961134 0.57124095292118 BMP7/ADRB1/ARL4A 3 GO:0070231 T cell apoptotic process 3/742 50/18722 0.318190003961134 0.57124095292118 RPS6/GLI3/DOCK8 3 GO:0090102 cochlea development 3/742 50/18722 0.318190003961134 0.57124095292118 IFT27/GATA3/HES1 3 GO:0099054 presynapse assembly 3/742 50/18722 0.318190003961134 0.57124095292118 APP/EIF4G1/SDCBP 3 GO:1904036 negative regulation of epithelial cell apoptotic process 3/742 50/18722 0.318190003961134 0.57124095292118 TCF7L2/SRSF6/GATA3 3 GO:0002702 positive regulation of production of molecular mediator of immune response 6/742 117/18722 0.319102889104253 0.57124095292118 TFRC/CD81/CD55/DHX36/RIF1/GATA3 6 GO:0072676 lymphocyte migration 6/742 117/18722 0.319102889104253 0.57124095292118 APP/PLEC/MIA3/GATA3/DOCK8/RHOA 6 GO:0030032 lamellipodium assembly 4/742 72/18722 0.319213547377353 0.57124095292118 ITGB1/WASF2/CDC42/CAPZB 4 GO:0043903 regulation of biological process involved in symbiotic interaction 4/742 72/18722 0.319213547377353 0.57124095292118 ITGAV/P4HB/CAV1/DDB1 4 GO:0055021 regulation of cardiac muscle tissue growth 4/742 72/18722 0.319213547377353 0.57124095292118 TGFBR3/GJA1/CITED2/YY1 4 GO:1901880 negative regulation of protein depolymerization 4/742 72/18722 0.319213547377353 0.57124095292118 SPTAN1/SPTBN1/TRIOBP/CAPZB 4 GO:0006633 fatty acid biosynthetic process 8/742 163/18722 0.319410384244414 0.57124095292118 ACSS1/MIF/HACD3/DEGS1/ANXA1/ACADVL/PTGES3/GPX4 8 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 11/742 233/18722 0.319597650011938 0.57124095292118 ADGRG1/PSAP/LGR5/LGR4/ATP2B4/ADRB1/AKAP13/WASF2/GNAQ/ADM/GNA12 11 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 2/742 29/18722 0.320090405423802 0.57124095292118 TNRC6A/TNRC6B 2 GO:0000305 response to oxygen radical 2/742 29/18722 0.320090405423802 0.57124095292118 SOD3/BMP7 2 GO:0003209 cardiac atrium morphogenesis 2/742 29/18722 0.320090405423802 0.57124095292118 SOX4/ISL1 2 GO:0006656 phosphatidylcholine biosynthetic process 2/742 29/18722 0.320090405423802 0.57124095292118 SLC44A2/CDS1 2 GO:0010390 histone monoubiquitination 2/742 29/18722 0.320090405423802 0.57124095292118 DDB1/SKP1 2 GO:0010458 exit from mitosis 2/742 29/18722 0.320090405423802 0.57124095292118 RPL24/UBE2C 2 GO:0010592 positive regulation of lamellipodium assembly 2/742 29/18722 0.320090405423802 0.57124095292118 WASF2/CDC42 2 GO:0010955 negative regulation of protein processing 2/742 29/18722 0.320090405423802 0.57124095292118 GLG1/TMEM59 2 GO:0015868 purine ribonucleotide transport 2/742 29/18722 0.320090405423802 0.57124095292118 GJA1/SLC19A1 2 GO:0021591 ventricular system development 2/742 29/18722 0.320090405423802 0.57124095292118 SEMA6D/CDK6 2 GO:0033028 myeloid cell apoptotic process 2/742 29/18722 0.320090405423802 0.57124095292118 CTSL/ANXA1 2 GO:0034311 diol metabolic process 2/742 29/18722 0.320090405423802 0.57124095292118 PLPP3/ASAH1 2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity 2/742 29/18722 0.320090405423802 0.57124095292118 EGFR/CKS1B 2 GO:0048665 neuron fate specification 2/742 29/18722 0.320090405423802 0.57124095292118 ISL1/GLI3 2 GO:0060441 epithelial tube branching involved in lung morphogenesis 2/742 29/18722 0.320090405423802 0.57124095292118 DAG1/DLG5 2 GO:0062098 regulation of programmed necrotic cell death 2/742 29/18722 0.320090405423802 0.57124095292118 CAV1/ASAH1 2 GO:0070198 protein localization to chromosome, telomeric region 2/742 29/18722 0.320090405423802 0.57124095292118 ATRX/CCT3 2 GO:0071549 cellular response to dexamethasone stimulus 2/742 29/18722 0.320090405423802 0.57124095292118 EGFR/SERPINF1 2 GO:0090025 regulation of monocyte chemotaxis 2/742 29/18722 0.320090405423802 0.57124095292118 DUSP1/LGMN 2 GO:1901017 negative regulation of potassium ion transmembrane transporter activity 2/742 29/18722 0.320090405423802 0.57124095292118 CAV1/ANK3 2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 2/742 29/18722 0.320090405423802 0.57124095292118 TPT1/MIF 2 GO:1902430 negative regulation of amyloid-beta formation 2/742 29/18722 0.320090405423802 0.57124095292118 RTN4/ROCK1 2 GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus 2/742 29/18722 0.320090405423802 0.57124095292118 SEMA6A/ATP2B4 2 GO:1903318 negative regulation of protein maturation 2/742 29/18722 0.320090405423802 0.57124095292118 GLG1/TMEM59 2 GO:1903902 positive regulation of viral life cycle 2/742 29/18722 0.320090405423802 0.57124095292118 P4HB/DDB1 2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining 2/742 29/18722 0.320090405423802 0.57124095292118 PRKDC/RIF1 2 GO:1901361 organic cyclic compound catabolic process 22/742 495/18722 0.320378685056297 0.57124095292118 KCNQ1OT1/FUS/ZFP36L1/NPM1/TNRC6A/HSPA1A/UPF2/TNRC6B/YBX1/HSPA1B/ROCK1/PUM1/TET2/DHX36/CELF1/LARP1/CIRBP/DDX5/HNRNPC/CYP19A1/SSB/BLVRA 22 GO:0030217 T cell differentiation 12/742 257/18722 0.321873318806286 0.57124095292118 CD46/CTSL/RPS6/SOX4/EGR1/PRKDC/ZFP36L1/ANXA1/GLI3/FOXP1/GATA3/RHOA 12 GO:0010876 lipid localization 20/742 448/18722 0.323927043324852 0.57124095292118 LRP1/ITGAV/SLC2A1/PSAP/KCNN4/CAV1/SLC27A2/ANXA1/CROT/LRP10/PLIN2/ATP10D/CDS1/SYT7/KDM5B/NFKBIA/MEST/CLN3/HEXB/CYP19A1 20 GO:0008585 female gonad development 5/742 95/18722 0.324280341513603 0.57124095292118 HSPA5/ADAMTS1/NR2F2/ARID5B/CYP19A1 5 GO:0042773 ATP synthesis coupled electron transport 5/742 95/18722 0.324280341513603 0.57124095292118 COX6A1/NDUFB9/UQCRH/COX8C/COX5A 5 GO:0042775 mitochondrial ATP synthesis coupled electron transport 5/742 95/18722 0.324280341513603 0.57124095292118 COX6A1/NDUFB9/UQCRH/COX8C/COX5A 5 GO:0048709 oligodendrocyte differentiation 5/742 95/18722 0.324280341513603 0.57124095292118 DAG1/GLI3/NF1/NCSTN/HES1 5 GO:0016241 regulation of macroautophagy 7/742 141/18722 0.326240984142585 0.57124095292118 GAPDH/VPS13C/LARP1/ATP6V1B1/VDAC1/ATP6V0B/CLN3 7 GO:0050921 positive regulation of chemotaxis 7/742 141/18722 0.326240984142585 0.57124095292118 MET/NRP1/CALR/TMSB4X/LGMN/TPBG/HSPB1 7 GO:0030100 regulation of endocytosis 10/742 211/18722 0.327044136004043 0.57124095292118 LRP1/ITGAV/LRPAP1/AAK1/CAV1/ROCK1/CALM1/CLN3/CDC42/SDCBP 10 GO:0032732 positive regulation of interleukin-1 production 4/742 73/18722 0.328264894808661 0.57124095292118 APP/EGR1/ISL1/HSPB1 4 GO:0099518 vesicle cytoskeletal trafficking 4/742 73/18722 0.328264894808661 0.57124095292118 DYNC1H1/KIF5B/ACTN4/CLN3 4 GO:1904427 positive regulation of calcium ion transmembrane transport 4/742 73/18722 0.328264894808661 0.57124095292118 GSTO1/SLC9A1/CALM1/CALM2 4 GO:0009948 anterior/posterior axis specification 3/742 51/18722 0.329151336796817 0.57124095292118 WLS/PGAP1/DDIT3 3 GO:0010874 regulation of cholesterol efflux 3/742 51/18722 0.329151336796817 0.57124095292118 LRP1/CAV1/NFKBIA 3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 3/742 51/18722 0.329151336796817 0.57124095292118 ASH1L/USP10/RHOA 3 GO:0045668 negative regulation of osteoblast differentiation 3/742 51/18722 0.329151336796817 0.57124095292118 CRIM1/LRP5/CDK6 3 GO:0051339 regulation of lyase activity 3/742 51/18722 0.329151336796817 0.57124095292118 AKAP9/NF1/PHPT1 3 GO:0060043 regulation of cardiac muscle cell proliferation 3/742 51/18722 0.329151336796817 0.57124095292118 TGFBR3/GJA1/CITED2 3 GO:0030510 regulation of BMP signaling pathway 5/742 96/18722 0.332150663142045 0.57124095292118 LRP2/FBN1/CRIM1/FSTL1/HES1 5 GO:0055017 cardiac muscle tissue growth 5/742 96/18722 0.332150663142045 0.57124095292118 TGFBR3/GJA1/AKAP13/CITED2/YY1 5 GO:1904035 regulation of epithelial cell apoptotic process 5/742 96/18722 0.332150663142045 0.57124095292118 ZFP36L1/TCF7L2/SRSF6/GATA3/PDCD4 5 GO:0046467 membrane lipid biosynthetic process 7/742 142/18722 0.332668565208247 0.57124095292118 ORMDL1/HACD3/PLPP3/DEGS1/GPAA1/PGAP1/ASAH1 7 GO:0001820 serotonin secretion 1/742 10/18722 0.332684255375351 0.57124095292118 SLC6A4 1 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 1/742 10/18722 0.332684255375351 0.57124095292118 CD81 1 GO:0002524 hypersensitivity 1/742 10/18722 0.332684255375351 0.57124095292118 GATA3 1 GO:0003163 sinoatrial node development 1/742 10/18722 0.332684255375351 0.57124095292118 ISL1 1 GO:0003183 mitral valve morphogenesis 1/742 10/18722 0.332684255375351 0.57124095292118 SOX4 1 GO:0005984 disaccharide metabolic process 1/742 10/18722 0.332684255375351 0.57124095292118 GAA 1 GO:0006012 galactose metabolic process 1/742 10/18722 0.332684255375351 0.57124095292118 GLB1 1 GO:0006228 UTP biosynthetic process 1/742 10/18722 0.332684255375351 0.57124095292118 NME3 1 GO:0006646 phosphatidylethanolamine biosynthetic process 1/742 10/18722 0.332684255375351 0.57124095292118 PISD 1 GO:0006735 NADH regeneration 1/742 10/18722 0.332684255375351 0.57124095292118 ENO1 1 GO:0007028 cytoplasm organization 1/742 10/18722 0.332684255375351 0.57124095292118 KIF5B 1 GO:0009750 response to fructose 1/742 10/18722 0.332684255375351 0.57124095292118 KRT18 1 GO:0010172 embryonic body morphogenesis 1/742 10/18722 0.332684255375351 0.57124095292118 DAG1 1 GO:0010992 ubiquitin recycling 1/742 10/18722 0.332684255375351 0.57124095292118 UBE2C 1 GO:0015808 L-alanine transport 1/742 10/18722 0.332684255375351 0.57124095292118 SLC3A2 1 GO:0015911 long-chain fatty acid import across plasma membrane 1/742 10/18722 0.332684255375351 0.57124095292118 SLC2A1 1 GO:0017085 response to insecticide 1/742 10/18722 0.332684255375351 0.57124095292118 UBA52 1 GO:0019062 virion attachment to host cell 1/742 10/18722 0.332684255375351 0.57124095292118 CD81 1 GO:0019532 oxalate transport 1/742 10/18722 0.332684255375351 0.57124095292118 SLC26A2 1 GO:0022400 regulation of rhodopsin mediated signaling pathway 1/742 10/18722 0.332684255375351 0.57124095292118 NMT1 1 GO:0030388 fructose 1,6-bisphosphate metabolic process 1/742 10/18722 0.332684255375351 0.57124095292118 ALDOA 1 GO:0031125 rRNA 3'-end processing 1/742 10/18722 0.332684255375351 0.57124095292118 RPS21 1 GO:0031642 negative regulation of myelination 1/742 10/18722 0.332684255375351 0.57124095292118 CTSC 1 GO:0031943 regulation of glucocorticoid metabolic process 1/742 10/18722 0.332684255375351 0.57124095292118 ATP1A1 1 GO:0032025 response to cobalt ion 1/742 10/18722 0.332684255375351 0.57124095292118 SERPINF1 1 GO:0032070 regulation of deoxyribonuclease activity 1/742 10/18722 0.332684255375351 0.57124095292118 NPM1 1 GO:0032253 dense core granule localization 1/742 10/18722 0.332684255375351 0.57124095292118 KIF5B 1 GO:0032275 luteinizing hormone secretion 1/742 10/18722 0.332684255375351 0.57124095292118 CGA 1 GO:0033131 regulation of glucokinase activity 1/742 10/18722 0.332684255375351 0.57124095292118 RANBP2 1 GO:0034085 establishment of sister chromatid cohesion 1/742 10/18722 0.332684255375351 0.57124095292118 NIPBL 1 GO:0035376 sterol import 1/742 10/18722 0.332684255375351 0.57124095292118 LRP1 1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway 1/742 10/18722 0.332684255375351 0.57124095292118 GATA3 1 GO:0042989 sequestering of actin monomers 1/742 10/18722 0.332684255375351 0.57124095292118 TMSB4X 1 GO:0042996 regulation of Golgi to plasma membrane protein transport 1/742 10/18722 0.332684255375351 0.57124095292118 CLN3 1 GO:0044848 biological phase 1/742 10/18722 0.332684255375351 0.57124095292118 FERMT1 1 GO:0045625 regulation of T-helper 1 cell differentiation 1/742 10/18722 0.332684255375351 0.57124095292118 ANXA1 1 GO:0045792 negative regulation of cell size 1/742 10/18722 0.332684255375351 0.57124095292118 RHOA 1 GO:0048194 Golgi vesicle budding 1/742 10/18722 0.332684255375351 0.57124095292118 TMED9 1 GO:0048251 elastic fiber assembly 1/742 10/18722 0.332684255375351 0.57124095292118 LTBP3 1 GO:0048262 determination of dorsal/ventral asymmetry 1/742 10/18722 0.332684255375351 0.57124095292118 DDIT3 1 GO:0048672 positive regulation of collateral sprouting 1/742 10/18722 0.332684255375351 0.57124095292118 LRP1 1 GO:0048703 embryonic viscerocranium morphogenesis 1/742 10/18722 0.332684255375351 0.57124095292118 NIPBL 1 GO:0051351 positive regulation of ligase activity 1/742 10/18722 0.332684255375351 0.57124095292118 TMSB4X 1 GO:0051660 establishment of centrosome localization 1/742 10/18722 0.332684255375351 0.57124095292118 DLG1 1 GO:0060068 vagina development 1/742 10/18722 0.332684255375351 0.57124095292118 LRP2 1 GO:0060272 embryonic skeletal joint morphogenesis 1/742 10/18722 0.332684255375351 0.57124095292118 BMP7 1 GO:0060513 prostatic bud formation 1/742 10/18722 0.332684255375351 0.57124095292118 BMP7 1 GO:0060736 prostate gland growth 1/742 10/18722 0.332684255375351 0.57124095292118 PSAP 1 GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 1/742 10/18722 0.332684255375351 0.57124095292118 SERPINF1 1 GO:0061085 regulation of histone H3-K27 methylation 1/742 10/18722 0.332684255375351 0.57124095292118 GATA3 1 GO:0061621 canonical glycolysis 1/742 10/18722 0.332684255375351 0.57124095292118 ENO1 1 GO:0061718 glucose catabolic process to pyruvate 1/742 10/18722 0.332684255375351 0.57124095292118 ENO1 1 GO:0070091 glucagon secretion 1/742 10/18722 0.332684255375351 0.57124095292118 SYT7 1 GO:0070092 regulation of glucagon secretion 1/742 10/18722 0.332684255375351 0.57124095292118 SYT7 1 GO:0070508 cholesterol import 1/742 10/18722 0.332684255375351 0.57124095292118 LRP1 1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum 1/742 10/18722 0.332684255375351 0.57124095292118 OS9 1 GO:0071372 cellular response to follicle-stimulating hormone stimulus 1/742 10/18722 0.332684255375351 0.57124095292118 POR 1 GO:0071421 manganese ion transmembrane transport 1/742 10/18722 0.332684255375351 0.57124095292118 TMEM165 1 GO:0071803 positive regulation of podosome assembly 1/742 10/18722 0.332684255375351 0.57124095292118 RHOA 1 GO:0072070 loop of Henle development 1/742 10/18722 0.332684255375351 0.57124095292118 IRX2 1 GO:0072178 nephric duct morphogenesis 1/742 10/18722 0.332684255375351 0.57124095292118 GATA3 1 GO:0072378 blood coagulation, fibrin clot formation 1/742 10/18722 0.332684255375351 0.57124095292118 FBLN1 1 GO:0090647 modulation of age-related behavioral decline 1/742 10/18722 0.332684255375351 0.57124095292118 APP 1 GO:0097278 complement-dependent cytotoxicity 1/742 10/18722 0.332684255375351 0.57124095292118 CD55 1 GO:0098903 regulation of membrane repolarization during action potential 1/742 10/18722 0.332684255375351 0.57124095292118 CAV1 1 GO:0098917 retrograde trans-synaptic signaling 1/742 10/18722 0.332684255375351 0.57124095292118 DAG1 1 GO:0099519 dense core granule cytoskeletal transport 1/742 10/18722 0.332684255375351 0.57124095292118 KIF5B 1 GO:0099532 synaptic vesicle endosomal processing 1/742 10/18722 0.332684255375351 0.57124095292118 EEA1 1 GO:0099639 neurotransmitter receptor transport, endosome to plasma membrane 1/742 10/18722 0.332684255375351 0.57124095292118 RAB11A 1 GO:1900246 positive regulation of RIG-I signaling pathway 1/742 10/18722 0.332684255375351 0.57124095292118 PUM1 1 GO:1901203 positive regulation of extracellular matrix assembly 1/742 10/18722 0.332684255375351 0.57124095292118 DAG1 1 GO:1901725 regulation of histone deacetylase activity 1/742 10/18722 0.332684255375351 0.57124095292118 KDM5A 1 GO:1901950 dense core granule transport 1/742 10/18722 0.332684255375351 0.57124095292118 KIF5B 1 GO:1901978 positive regulation of cell cycle checkpoint 1/742 10/18722 0.332684255375351 0.57124095292118 TPR 1 GO:1902023 L-arginine transport 1/742 10/18722 0.332684255375351 0.57124095292118 SLC38A9 1 GO:1902513 regulation of organelle transport along microtubule 1/742 10/18722 0.332684255375351 0.57124095292118 LAMP1 1 GO:1902946 protein localization to early endosome 1/742 10/18722 0.332684255375351 0.57124095292118 NRP1 1 GO:1903826 arginine transmembrane transport 1/742 10/18722 0.332684255375351 0.57124095292118 SLC38A9 1 GO:1903867 extraembryonic membrane development 1/742 10/18722 0.332684255375351 0.57124095292118 BMP7 1 GO:1903980 positive regulation of microglial cell activation 1/742 10/18722 0.332684255375351 0.57124095292118 CTSC 1 GO:1904851 positive regulation of establishment of protein localization to telomere 1/742 10/18722 0.332684255375351 0.57124095292118 CCT3 1 GO:1905456 regulation of lymphoid progenitor cell differentiation 1/742 10/18722 0.332684255375351 0.57124095292118 HES1 1 GO:1905941 positive regulation of gonad development 1/742 10/18722 0.332684255375351 0.57124095292118 CITED2 1 GO:1990253 cellular response to leucine starvation 1/742 10/18722 0.332684255375351 0.57124095292118 EIF2AK4 1 GO:1990535 neuron projection maintenance 1/742 10/18722 0.332684255375351 0.57124095292118 APP 1 GO:2000018 regulation of male gonad development 1/742 10/18722 0.332684255375351 0.57124095292118 CITED2 1 GO:2000121 regulation of removal of superoxide radicals 1/742 10/18722 0.332684255375351 0.57124095292118 BMP7 1 GO:2000288 positive regulation of myoblast proliferation 1/742 10/18722 0.332684255375351 0.57124095292118 MALAT1 1 GO:2000425 regulation of apoptotic cell clearance 1/742 10/18722 0.332684255375351 0.57124095292118 TGM2 1 GO:2000434 regulation of protein neddylation 1/742 10/18722 0.332684255375351 0.57124095292118 EPAS1 1 GO:2000510 positive regulation of dendritic cell chemotaxis 1/742 10/18722 0.332684255375351 0.57124095292118 CALR 1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation 1/742 10/18722 0.332684255375351 0.57124095292118 WASF2 1 GO:2001223 negative regulation of neuron migration 1/742 10/18722 0.332684255375351 0.57124095292118 ADGRG1 1 GO:2001225 regulation of chloride transport 1/742 10/18722 0.332684255375351 0.57124095292118 GABRE 1 GO:0010906 regulation of glucose metabolic process 6/742 119/18722 0.333173857489413 0.571265333399243 DDB1/PMAIP1/RANBP2/SLC35B4/IGF2/LCMT1 6 GO:0007202 activation of phospholipase C activity 2/742 30/18722 0.33478390174506 0.571265333399243 EGFR/GNAQ 2 GO:0008209 androgen metabolic process 2/742 30/18722 0.33478390174506 0.571265333399243 ADM/CYP19A1 2 GO:0010453 regulation of cell fate commitment 2/742 30/18722 0.33478390174506 0.571265333399243 LMO4/HES1 2 GO:0015865 purine nucleotide transport 2/742 30/18722 0.33478390174506 0.571265333399243 GJA1/SLC19A1 2 GO:0017145 stem cell division 2/742 30/18722 0.33478390174506 0.571265333399243 NCOA3/LBH 2 GO:0019674 NAD metabolic process 2/742 30/18722 0.33478390174506 0.571265333399243 LDHA/ENO1 2 GO:0031365 N-terminal protein amino acid modification 2/742 30/18722 0.33478390174506 0.571265333399243 SOX4/NMT1 2 GO:0034694 response to prostaglandin 2/742 30/18722 0.33478390174506 0.571265333399243 TGFBR3/YY1 2 GO:0036296 response to increased oxygen levels 2/742 30/18722 0.33478390174506 0.571265333399243 CAV1/ATP6AP1 2 GO:0043032 positive regulation of macrophage activation 2/742 30/18722 0.33478390174506 0.571265333399243 JUND/CTSC 2 GO:0044030 regulation of DNA methylation 2/742 30/18722 0.33478390174506 0.571265333399243 MPHOSPH8/PARP1 2 GO:0048147 negative regulation of fibroblast proliferation 2/742 30/18722 0.33478390174506 0.571265333399243 FTH1/NF1 2 GO:0048799 animal organ maturation 2/742 30/18722 0.33478390174506 0.571265333399243 GATA3/RHOA 2 GO:0051491 positive regulation of filopodium assembly 2/742 30/18722 0.33478390174506 0.571265333399243 NRP1/CDC42 2 GO:0060603 mammary gland duct morphogenesis 2/742 30/18722 0.33478390174506 0.571265333399243 LRP5/KDM5B 2 GO:0070168 negative regulation of biomineral tissue development 2/742 30/18722 0.33478390174506 0.571265333399243 LTBP3/ROCK1 2 GO:0090151 establishment of protein localization to mitochondrial membrane 2/742 30/18722 0.33478390174506 0.571265333399243 NMT1/CALM1 2 GO:0046578 regulation of Ras protein signal transduction 9/742 189/18722 0.334895628648625 0.571265333399243 ADGRG1/ITGB1/MET/KANK1/NRP1/AKAP13/RASA1/EPS8L1/DYNLT1 9 GO:0051881 regulation of mitochondrial membrane potential 4/742 74/18722 0.337330615621325 0.575220311069847 ARL6IP5/SLC25A36/PMAIP1/PARP1 4 GO:0006909 phagocytosis 14/742 308/18722 0.337962045774095 0.576098173265711 LRP1/ITGAV/ITGB1/MET/COLEC12/CALR/ANXA1/KIAA1109/LMAN2/SYT7/CLN3/CDC42/TGM2/ANXA3 14 GO:0010596 negative regulation of endothelial cell migration 5/742 97/18722 0.340038217254502 0.578559245895338 SERPINF1/ATP2B4/NR2F2/RHOA/CSNK2B 5 GO:0043255 regulation of carbohydrate biosynthetic process 5/742 97/18722 0.340038217254502 0.578559245895338 DDB1/RANBP2/SLC35B4/CLTC/IGF2 5 GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 3/742 52/18722 0.340108512161956 0.578559245895338 PLPP3/LMAN2/ERGIC2 3 GO:0030514 negative regulation of BMP signaling pathway 3/742 52/18722 0.340108512161956 0.578559245895338 LRP2/FBN1/CRIM1 3 GO:0045010 actin nucleation 3/742 52/18722 0.340108512161956 0.578559245895338 IQGAP2/WASF2/ARPC3 3 GO:0060071 Wnt signaling pathway, planar cell polarity pathway 3/742 52/18722 0.340108512161956 0.578559245895338 ZNRF3/CDC42/RHOA 3 GO:0034728 nucleosome organization 8/742 167/18722 0.343208428851533 0.583419998325044 BPTF/ATRX/NPM1/ARID1A/BRD2/HP1BP3/RSF1/HMGA1 8 GO:0002292 T cell differentiation involved in immune response 4/742 75/18722 0.346405456877463 0.583419998325044 CD46/ANXA1/FOXP1/GATA3 4 GO:0006094 gluconeogenesis 4/742 75/18722 0.346405456877463 0.583419998325044 TPI1/DDB1/RANBP2/SLC35B4 4 GO:0045913 positive regulation of carbohydrate metabolic process 4/742 75/18722 0.346405456877463 0.583419998325044 APP/DDB1/PMAIP1/IGF2 4 GO:0048662 negative regulation of smooth muscle cell proliferation 4/742 75/18722 0.346405456877463 0.583419998325044 SF1/GNA12/RHOA/PDCD4 4 GO:1903363 negative regulation of cellular protein catabolic process 4/742 75/18722 0.346405456877463 0.583419998325044 RPL23/EIF3H/ATRAID/SDCBP 4 GO:0038127 ERBB signaling pathway 6/742 121/18722 0.347317024783512 0.583419998325044 EGFR/EFEMP1/IQGAP1/RTN4/LGMN/PTPN12 6 GO:0002230 positive regulation of defense response to virus by host 2/742 31/18722 0.349382308916813 0.583419998325044 TRIM44/EIF2AK4 2 GO:0002717 positive regulation of natural killer cell mediated immunity 2/742 31/18722 0.349382308916813 0.583419998325044 CADM1/LAMP1 2 GO:0008045 motor neuron axon guidance 2/742 31/18722 0.349382308916813 0.583419998325044 MYCBP2/NRP1 2 GO:0016577 histone demethylation 2/742 31/18722 0.349382308916813 0.583419998325044 KDM5A/KDM5B 2 GO:0030212 hyaluronan metabolic process 2/742 31/18722 0.349382308916813 0.583419998325044 ITIH5/CLTC 2 GO:0031063 regulation of histone deacetylation 2/742 31/18722 0.349382308916813 0.583419998325044 KDM5A/NIPBL 2 GO:0032148 activation of protein kinase B activity 2/742 31/18722 0.349382308916813 0.583419998325044 PPIA/TXN 2 GO:0033238 regulation of cellular amine metabolic process 2/742 31/18722 0.349382308916813 0.583419998325044 ATP2B4/CLN3 2 GO:0036474 cell death in response to hydrogen peroxide 2/742 31/18722 0.349382308916813 0.583419998325044 MET/TXN 2 GO:0036475 neuron death in response to oxidative stress 2/742 31/18722 0.349382308916813 0.583419998325044 ARL6IP5/PARP1 2 GO:0042133 neurotransmitter metabolic process 2/742 31/18722 0.349382308916813 0.583419998325044 SLC6A4/CLN3 2 GO:0043171 peptide catabolic process 2/742 31/18722 0.349382308916813 0.583419998325044 ENPEP/CPQ 2 GO:0048384 retinoic acid receptor signaling pathway 2/742 31/18722 0.349382308916813 0.583419998325044 CALR/ACTN4 2 GO:0048566 embryonic digestive tract development 2/742 31/18722 0.349382308916813 0.583419998325044 GLI3/NIPBL 2 GO:0048710 regulation of astrocyte differentiation 2/742 31/18722 0.349382308916813 0.583419998325044 IL6ST/HES1 2 GO:0051569 regulation of histone H3-K4 methylation 2/742 31/18722 0.349382308916813 0.583419998325044 RTF1/GATA3 2 GO:0060055 angiogenesis involved in wound healing 2/742 31/18722 0.349382308916813 0.583419998325044 DAG1/GPX1 2 GO:0110150 negative regulation of biomineralization 2/742 31/18722 0.349382308916813 0.583419998325044 LTBP3/ROCK1 2 GO:1905144 response to acetylcholine 2/742 31/18722 0.349382308916813 0.583419998325044 ATP2B4/GNAQ 2 GO:1905145 cellular response to acetylcholine 2/742 31/18722 0.349382308916813 0.583419998325044 ATP2B4/GNAQ 2 GO:2000144 positive regulation of DNA-templated transcription, initiation 2/742 31/18722 0.349382308916813 0.583419998325044 JUN/DHX36 2 GO:0002707 negative regulation of lymphocyte mediated immunity 3/742 53/18722 0.351052916871715 0.583419998325044 CD46/CD55/SERPINB9 3 GO:0032210 regulation of telomere maintenance via telomerase 3/742 53/18722 0.351052916871715 0.583419998325044 HNRNPA1/HNRNPC/CCT3 3 GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 3/742 53/18722 0.351052916871715 0.583419998325044 MET/ATP2B4/ADM 3 GO:0099172 presynapse organization 3/742 53/18722 0.351052916871715 0.583419998325044 APP/EIF4G1/SDCBP 3 GO:0002688 regulation of leukocyte chemotaxis 6/742 122/18722 0.354409308147497 0.583419998325044 DUSP1/MIF/DPP4/JAM3/CALR/LGMN 6 GO:0051928 positive regulation of calcium ion transport 6/742 122/18722 0.354409308147497 0.583419998325044 ATP2B1/CAV1/GSTO1/SLC9A1/CALM1/CALM2 6 GO:1990266 neutrophil migration 6/742 122/18722 0.354409308147497 0.583419998325044 CSF3R/BSG/DPP4/JAM3/S100A9/PPIA 6 GO:0000075 cell cycle checkpoint signaling 8/742 169/18722 0.355201910009696 0.583419998325044 DUSP1/SOX4/RPL26/PRKDC/PPP1R10/TPR/EIF2AK4/LCMT1 8 GO:0031214 biomineral tissue development 8/742 169/18722 0.355201910009696 0.583419998325044 FBN2/ATP2B1/LGR4/BMP7/LTBP3/ROCK1/NOTUM/ATRAID 8 GO:0006305 DNA alkylation 4/742 76/18722 0.355484292841704 0.583419998325044 FOS/ATRX/MPHOSPH8/PARP1 4 GO:0006306 DNA methylation 4/742 76/18722 0.355484292841704 0.583419998325044 FOS/ATRX/MPHOSPH8/PARP1 4 GO:0008652 cellular amino acid biosynthetic process 4/742 76/18722 0.355484292841704 0.583419998325044 ATP2B4/MTR/SERINC3/CLN3 4 GO:0043536 positive regulation of blood vessel endothelial cell migration 4/742 76/18722 0.355484292841704 0.583419998325044 NRP1/TMSB4X/ANXA1/HSPB1 4 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 5/742 99/18722 0.355850993008416 0.583419998325044 TPT1/MIF/RPL26/PRKDC/TMEM109 5 GO:0021510 spinal cord development 5/742 99/18722 0.355850993008416 0.583419998325044 SOX4/LMO4/ISL1/GLI3/NF1 5 GO:0021549 cerebellum development 5/742 99/18722 0.355850993008416 0.583419998325044 HSPA5/NAGLU/NCSTN/RERE/SDF4 5 GO:0060996 dendritic spine development 5/742 99/18722 0.355850993008416 0.583419998325044 DLG5/PPP1R9A/CFL1/DHX36/CDC42 5 GO:0010675 regulation of cellular carbohydrate metabolic process 7/742 146/18722 0.358540243793716 0.583419998325044 DDB1/PMAIP1/RANBP2/NCOR1/SLC35B4/IGF2/LCMT1 7 GO:0001967 suckling behavior 1/742 11/18722 0.359145792491186 0.583419998325044 APP 1 GO:0002732 positive regulation of dendritic cell cytokine production 1/742 11/18722 0.359145792491186 0.583419998325044 DHX36 1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 1/742 11/18722 0.359145792491186 0.583419998325044 UQCRH 1 GO:0006183 GTP biosynthetic process 1/742 11/18722 0.359145792491186 0.583419998325044 NME3 1 GO:0006449 regulation of translational termination 1/742 11/18722 0.359145792491186 0.583419998325044 EIF5A 1 GO:0006527 arginine catabolic process 1/742 11/18722 0.359145792491186 0.583419998325044 ATP2B4 1 GO:0009235 cobalamin metabolic process 1/742 11/18722 0.359145792491186 0.583419998325044 MTR 1 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient 1/742 11/18722 0.359145792491186 0.583419998325044 ATP1A1 1 GO:0010269 response to selenium ion 1/742 11/18722 0.359145792491186 0.583419998325044 GPX1 1 GO:0010739 positive regulation of protein kinase A signaling 1/742 11/18722 0.359145792491186 0.583419998325044 MIF 1 GO:0014854 response to inactivity 1/742 11/18722 0.359145792491186 0.583419998325044 DAG1 1 GO:0019048 modulation by virus of host process 1/742 11/18722 0.359145792491186 0.583419998325044 DAG1 1 GO:0030432 peristalsis 1/742 11/18722 0.359145792491186 0.583419998325044 DLG1 1 GO:0031442 positive regulation of mRNA 3'-end processing 1/742 11/18722 0.359145792491186 0.583419998325044 DHX36 1 GO:0032276 regulation of gonadotropin secretion 1/742 11/18722 0.359145792491186 0.583419998325044 GJA1 1 GO:0032351 negative regulation of hormone metabolic process 1/742 11/18722 0.359145792491186 0.583419998325044 ATP1A1 1 GO:0032610 interleukin-1 alpha production 1/742 11/18722 0.359145792491186 0.583419998325044 ISL1 1 GO:0032650 regulation of interleukin-1 alpha production 1/742 11/18722 0.359145792491186 0.583419998325044 ISL1 1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway 1/742 11/18722 0.359145792491186 0.583419998325044 PARP1 1 GO:0033327 Leydig cell differentiation 1/742 11/18722 0.359145792491186 0.583419998325044 SF1 1 GO:0033483 gas homeostasis 1/742 11/18722 0.359145792491186 0.583419998325044 CAV1 1 GO:0033625 positive regulation of integrin activation 1/742 11/18722 0.359145792491186 0.583419998325044 FERMT1 1 GO:0033632 regulation of cell-cell adhesion mediated by integrin 1/742 11/18722 0.359145792491186 0.583419998325044 DPP4 1 GO:0034163 regulation of toll-like receptor 9 signaling pathway 1/742 11/18722 0.359145792491186 0.583419998325044 RTN4 1 GO:0034454 microtubule anchoring at centrosome 1/742 11/18722 0.359145792491186 0.583419998325044 PCM1 1 GO:0034650 cortisol metabolic process 1/742 11/18722 0.359145792491186 0.583419998325044 CYP11A1 1 GO:0034770 histone H4-K20 methylation 1/742 11/18722 0.359145792491186 0.583419998325044 NSD1 1 GO:0034776 response to histamine 1/742 11/18722 0.359145792491186 0.583419998325044 DIAPH1 1 GO:0042167 heme catabolic process 1/742 11/18722 0.359145792491186 0.583419998325044 BLVRA 1 GO:0042447 hormone catabolic process 1/742 11/18722 0.359145792491186 0.583419998325044 CYP19A1 1 GO:0043312 neutrophil degranulation 1/742 11/18722 0.359145792491186 0.583419998325044 ANXA3 1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress 1/742 11/18722 0.359145792491186 0.583419998325044 EPAS1 1 GO:0044068 modulation by symbiont of host cellular process 1/742 11/18722 0.359145792491186 0.583419998325044 SERPINB9 1 GO:0045060 negative thymic T cell selection 1/742 11/18722 0.359145792491186 0.583419998325044 GLI3 1 GO:0045628 regulation of T-helper 2 cell differentiation 1/742 11/18722 0.359145792491186 0.583419998325044 ANXA1 1 GO:0045793 positive regulation of cell size 1/742 11/18722 0.359145792491186 0.583419998325044 RB1CC1 1 GO:0046149 pigment catabolic process 1/742 11/18722 0.359145792491186 0.583419998325044 BLVRA 1 GO:0046598 positive regulation of viral entry into host cell 1/742 11/18722 0.359145792491186 0.583419998325044 P4HB 1 GO:0046643 regulation of gamma-delta T cell activation 1/742 11/18722 0.359145792491186 0.583419998325044 SOX4 1 GO:0046710 GDP metabolic process 1/742 11/18722 0.359145792491186 0.583419998325044 DLG1 1 GO:0046929 negative regulation of neurotransmitter secretion 1/742 11/18722 0.359145792491186 0.583419998325044 PPP1R9A 1 GO:0048103 somatic stem cell division 1/742 11/18722 0.359145792491186 0.583419998325044 LBH 1 GO:0048853 forebrain morphogenesis 1/742 11/18722 0.359145792491186 0.583419998325044 NF1 1 GO:0051081 nuclear membrane disassembly 1/742 11/18722 0.359145792491186 0.583419998325044 NEK6 1 GO:0051574 positive regulation of histone H3-K9 methylation 1/742 11/18722 0.359145792491186 0.583419998325044 RIF1 1 GO:0051610 serotonin uptake 1/742 11/18722 0.359145792491186 0.583419998325044 SLC6A4 1 GO:0060174 limb bud formation 1/742 11/18722 0.359145792491186 0.583419998325044 SOX4 1 GO:0060312 regulation of blood vessel remodeling 1/742 11/18722 0.359145792491186 0.583419998325044 CST3 1 GO:0060379 cardiac muscle cell myoblast differentiation 1/742 11/18722 0.359145792491186 0.583419998325044 ISL1 1 GO:0060579 ventral spinal cord interneuron fate commitment 1/742 11/18722 0.359145792491186 0.583419998325044 GLI3 1 GO:0060581 cell fate commitment involved in pattern specification 1/742 11/18722 0.359145792491186 0.583419998325044 GLI3 1 GO:0060742 epithelial cell differentiation involved in prostate gland development 1/742 11/18722 0.359145792491186 0.583419998325044 PSAP 1 GO:0060767 epithelial cell proliferation involved in prostate gland development 1/742 11/18722 0.359145792491186 0.583419998325044 SERPINF1 1 GO:0060837 blood vessel endothelial cell differentiation 1/742 11/18722 0.359145792491186 0.583419998325044 NRP1 1 GO:0061314 Notch signaling involved in heart development 1/742 11/18722 0.359145792491186 0.583419998325044 GALNT11 1 GO:0070203 regulation of establishment of protein localization to telomere 1/742 11/18722 0.359145792491186 0.583419998325044 CCT3 1 GO:0070778 L-aspartate transmembrane transport 1/742 11/18722 0.359145792491186 0.583419998325044 SLC1A5 1 GO:0071044 histone mRNA catabolic process 1/742 11/18722 0.359145792491186 0.583419998325044 SSB 1 GO:0071492 cellular response to UV-A 1/742 11/18722 0.359145792491186 0.583419998325044 MME 1 GO:0071888 macrophage apoptotic process 1/742 11/18722 0.359145792491186 0.583419998325044 CTSL 1 GO:0072205 metanephric collecting duct development 1/742 11/18722 0.359145792491186 0.583419998325044 DLG5 1 GO:0075294 positive regulation by symbiont of entry into host 1/742 11/18722 0.359145792491186 0.583419998325044 P4HB 1 GO:0075733 intracellular transport of virus 1/742 11/18722 0.359145792491186 0.583419998325044 DYNLT1 1 GO:0086016 AV node cell action potential 1/742 11/18722 0.359145792491186 0.583419998325044 GJA5 1 GO:0086027 AV node cell to bundle of His cell signaling 1/742 11/18722 0.359145792491186 0.583419998325044 GJA5 1 GO:0086070 SA node cell to atrial cardiac muscle cell communication 1/742 11/18722 0.359145792491186 0.583419998325044 GJA5 1 GO:0090205 positive regulation of cholesterol metabolic process 1/742 11/18722 0.359145792491186 0.583419998325044 POR 1 GO:0090309 positive regulation of DNA methylation-dependent heterochromatin assembly 1/742 11/18722 0.359145792491186 0.583419998325044 MPHOSPH8 1 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport 1/742 11/18722 0.359145792491186 0.583419998325044 SLC35B4 1 GO:0097494 regulation of vesicle size 1/742 11/18722 0.359145792491186 0.583419998325044 RAB11A 1 GO:0099022 vesicle tethering 1/742 11/18722 0.359145792491186 0.583419998325044 TRIP11 1 GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 1/742 11/18722 0.359145792491186 0.583419998325044 ATP2B4 1 GO:0140042 lipid droplet formation 1/742 11/18722 0.359145792491186 0.583419998325044 CDS1 1 GO:1900112 regulation of histone H3-K9 trimethylation 1/742 11/18722 0.359145792491186 0.583419998325044 ATRX 1 GO:1900222 negative regulation of amyloid-beta clearance 1/742 11/18722 0.359145792491186 0.583419998325044 LRPAP1 1 GO:1900426 positive regulation of defense response to bacterium 1/742 11/18722 0.359145792491186 0.583419998325044 GRN 1 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1/742 11/18722 0.359145792491186 0.583419998325044 NMT1 1 GO:1902033 regulation of hematopoietic stem cell proliferation 1/742 11/18722 0.359145792491186 0.583419998325044 N4BP2L2 1 GO:1902065 response to L-glutamate 1/742 11/18722 0.359145792491186 0.583419998325044 UFL1 1 GO:1902188 positive regulation of viral release from host cell 1/742 11/18722 0.359145792491186 0.583419998325044 DDB1 1 GO:1902337 regulation of apoptotic process involved in morphogenesis 1/742 11/18722 0.359145792491186 0.583419998325044 BMP7 1 GO:1903299 regulation of hexokinase activity 1/742 11/18722 0.359145792491186 0.583419998325044 RANBP2 1 GO:1904869 regulation of protein localization to Cajal body 1/742 11/18722 0.359145792491186 0.583419998325044 CCT3 1 GO:1904871 positive regulation of protein localization to Cajal body 1/742 11/18722 0.359145792491186 0.583419998325044 CCT3 1 GO:1905050 positive regulation of metallopeptidase activity 1/742 11/18722 0.359145792491186 0.583419998325044 CLDN4 1 GO:1905150 regulation of voltage-gated sodium channel activity 1/742 11/18722 0.359145792491186 0.583419998325044 KIF5B 1 GO:1905522 negative regulation of macrophage migration 1/742 11/18722 0.359145792491186 0.583419998325044 MIF 1 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 1/742 11/18722 0.359145792491186 0.583419998325044 LRP1 1 GO:2000392 regulation of lamellipodium morphogenesis 1/742 11/18722 0.359145792491186 0.583419998325044 KANK1 1 GO:2000615 regulation of histone H3-K9 acetylation 1/742 11/18722 0.359145792491186 0.583419998325044 GATA3 1 GO:2001053 regulation of mesenchymal cell apoptotic process 1/742 11/18722 0.359145792491186 0.583419998325044 BMP7 1 GO:0002683 negative regulation of immune system process 19/742 434/18722 0.360931562755882 0.586128178834338 FBN1/CD46/GRN/DUSP1/MIF/PRKDC/DPP4/DLG5/MIA3/ANXA1/CDK6/GLI3/DLG1/CD55/PCBP2/ADAR/GPX1/SERPINB9/PHPT1 19 GO:0007259 receptor signaling pathway via JAK-STAT 8/742 170/18722 0.361216868709518 0.586398728697015 CAV1/IL6ST/CSH1/ISL1/PRLR/IL10RB/LEPROT/HES1 8 GO:0030168 platelet activation 6/742 123/18722 0.361512046453598 0.586667621465561 IL6ST/ACTG1/PPIA/HSPB1/TLN1/MYL12A 6 GO:0035065 regulation of histone acetylation 3/742 54/18722 0.361976297616807 0.586667621465561 ISL1/BRD7/GATA3 3 GO:0060350 endochondral bone morphogenesis 3/742 54/18722 0.361976297616807 0.586667621465561 TRIP11/SERPINH1/POR 3 GO:0070228 regulation of lymphocyte apoptotic process 3/742 54/18722 0.361976297616807 0.586667621465561 SLC39A10/FOXP1/DOCK8 3 GO:2000179 positive regulation of neural precursor cell proliferation 3/742 54/18722 0.361976297616807 0.586667621465561 LRP2/ADGRG1/GLI3 3 GO:0006626 protein targeting to mitochondrion 5/742 100/18722 0.363769340941863 0.58704230689474 LMAN1/HUWE1/BCAP31/LEPROT/UBE2L3 5 GO:0009062 fatty acid catabolic process 5/742 100/18722 0.363769340941863 0.58704230689474 SLC27A2/CROT/ACADVL/HADHA/ETFA 5 GO:0046545 development of primary female sexual characteristics 5/742 100/18722 0.363769340941863 0.58704230689474 HSPA5/ADAMTS1/NR2F2/ARID5B/CYP19A1 5 GO:0003180 aortic valve morphogenesis 2/742 32/18722 0.3638700948768 0.58704230689474 ROCK1/GATA3 2 GO:0006506 GPI anchor biosynthetic process 2/742 32/18722 0.3638700948768 0.58704230689474 GPAA1/PGAP1 2 GO:0010743 regulation of macrophage derived foam cell differentiation 2/742 32/18722 0.3638700948768 0.58704230689474 ITGAV/NFKBIA 2 GO:0030431 sleep 2/742 32/18722 0.3638700948768 0.58704230689474 FOS/ADRB1 2 GO:0035883 enteroendocrine cell differentiation 2/742 32/18722 0.3638700948768 0.58704230689474 CDK6/HES1 2 GO:0045761 regulation of adenylate cyclase activity 2/742 32/18722 0.3638700948768 0.58704230689474 AKAP9/NF1 2 GO:0061036 positive regulation of cartilage development 2/742 32/18722 0.3638700948768 0.58704230689474 POR/GLI3 2 GO:0061037 negative regulation of cartilage development 2/742 32/18722 0.3638700948768 0.58704230689474 EFEMP1/LTBP3 2 GO:0090022 regulation of neutrophil chemotaxis 2/742 32/18722 0.3638700948768 0.58704230689474 DPP4/JAM3 2 GO:1901889 negative regulation of cell junction assembly 2/742 32/18722 0.3638700948768 0.58704230689474 LRP1/ROCK1 2 GO:0018209 peptidyl-serine modification 15/742 338/18722 0.363871162694675 0.58704230689474 EGFR/AKAP9/APP/TFRC/CAV1/MIF/PRKDC/PKN2/ATP2B4/EIF4G1/ROCK1/NSD1/TXN/PARP1/NEK6 15 GO:0046394 carboxylic acid biosynthetic process 14/742 314/18722 0.364332799719588 0.587595178130841 ACSS1/MGST3/MIF/SLC27A2/HACD3/ATP2B4/DEGS1/ANXA1/MTR/SERINC3/ACADVL/CLN3/PTGES3/GPX4 14 GO:1901983 regulation of protein acetylation 4/742 77/18722 0.364562128315629 0.587687052095536 SOX4/ISL1/BRD7/GATA3 4 GO:0071103 DNA conformation change 13/742 290/18722 0.364627695277898 0.587687052095536 ATRX/NPM1/ANXA1/BRD2/PURA/CHD2/HP1BP3/DHX36/RSF1/HMGB3/RAD50/HMGA1/BANF1 13 GO:1902652 secondary alcohol metabolic process 7/742 147/18722 0.365038823964005 0.588157792035938 APP/DHCR24/LRP5/POR/MBTPS1/ACADVL/CYP11A1 7 GO:0110148 biomineralization 8/742 171/18722 0.367241939940004 0.591514569058891 FBN2/ATP2B1/LGR4/BMP7/LTBP3/ROCK1/NOTUM/ATRAID 8 GO:0001909 leukocyte mediated cytotoxicity 6/742 124/18722 0.368622768811785 0.591814139044172 CTSC/CADM1/KIF5B/LAMP1/SERPINB9/TUBB4B 6 GO:0010508 positive regulation of autophagy 6/742 124/18722 0.368622768811785 0.591814139044172 UFL1/TMEM59/ROCK1/ATF6/LARP1/VDAC1 6 GO:0018105 peptidyl-serine phosphorylation 14/742 315/18722 0.368761345766558 0.591814139044172 EGFR/AKAP9/APP/TFRC/CAV1/MIF/PRKDC/PKN2/ATP2B4/EIF4G1/ROCK1/NSD1/TXN/NEK6 14 GO:0097530 granulocyte migration 7/742 148/18722 0.371545852790968 0.591814139044172 CSF3R/BSG/DPP4/JAM3/ANXA1/S100A9/PPIA 7 GO:0051963 regulation of synapse assembly 5/742 101/18722 0.371691179179213 0.591814139044172 APP/DLG5/EIF4G1/PPP1R9A/TPBG 5 GO:0010676 positive regulation of cellular carbohydrate metabolic process 3/742 55/18722 0.37287075897649 0.591814139044172 DDB1/PMAIP1/IGF2 3 GO:0048016 inositol phosphate-mediated signaling 3/742 55/18722 0.37287075897649 0.591814139044172 ATP2B4/NFAT5/SLC9A1 3 GO:0051898 negative regulation of protein kinase B signaling 3/742 55/18722 0.37287075897649 0.591814139044172 DAG1/DLG1/DDIT3 3 GO:0016053 organic acid biosynthetic process 14/742 316/18722 0.373197835277418 0.591814139044172 ACSS1/MGST3/MIF/SLC27A2/HACD3/ATP2B4/DEGS1/ANXA1/MTR/SERINC3/ACADVL/CLN3/PTGES3/GPX4 14 GO:0002221 pattern recognition receptor signaling pathway 8/742 172/18722 0.373275612009953 0.591814139044172 CAV1/LGR4/COLEC12/RTN4/HSPA1A/HSPA1B/PUM1/NFKBIA 8 GO:0019319 hexose biosynthetic process 4/742 78/18722 0.373634101518381 0.591814139044172 TPI1/DDB1/RANBP2/SLC35B4 4 GO:0016525 negative regulation of angiogenesis 7/742 149/18722 0.378059454005502 0.591814139044172 SEMA6A/SERPINF1/COL4A2/ADAMTS1/ATP2B4/ROCK1/GTF2I 7 GO:0045834 positive regulation of lipid metabolic process 7/742 149/18722 0.378059454005502 0.591814139044172 FLT1/POR/CD81/ANXA1/ADM/CDC42/CGA 7 GO:0001975 response to amphetamine 2/742 33/18722 0.378233104689563 0.591814139044172 RANBP2/CALM1 2 GO:0006482 protein demethylation 2/742 33/18722 0.378233104689563 0.591814139044172 KDM5A/KDM5B 2 GO:0006505 GPI anchor metabolic process 2/742 33/18722 0.378233104689563 0.591814139044172 GPAA1/PGAP1 2 GO:0008214 protein dealkylation 2/742 33/18722 0.378233104689563 0.591814139044172 KDM5A/KDM5B 2 GO:0010259 multicellular organism aging 2/742 33/18722 0.378233104689563 0.591814139044172 CTSV/SEC63 2 GO:0010984 regulation of lipoprotein particle clearance 2/742 33/18722 0.378233104689563 0.591814139044172 LRPAP1/CNPY2 2 GO:0032228 regulation of synaptic transmission, GABAergic 2/742 33/18722 0.378233104689563 0.591814139044172 KIF5B/CLN3 2 GO:0032633 interleukin-4 production 2/742 33/18722 0.378233104689563 0.591814139044172 DDIT3/GATA3 2 GO:0032673 regulation of interleukin-4 production 2/742 33/18722 0.378233104689563 0.591814139044172 DDIT3/GATA3 2 GO:0034110 regulation of homotypic cell-cell adhesion 2/742 33/18722 0.378233104689563 0.591814139044172 IL6ST/ANK3 2 GO:0035025 positive regulation of Rho protein signal transduction 2/742 33/18722 0.378233104689563 0.591814139044172 ADGRG1/AKAP13 2 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 2/742 33/18722 0.378233104689563 0.591814139044172 FLT1/CDC42 2 GO:0050901 leukocyte tethering or rolling 2/742 33/18722 0.378233104689563 0.591814139044172 ITGB1/ROCK1 2 GO:0071295 cellular response to vitamin 2/742 33/18722 0.378233104689563 0.591814139044172 ATP2B1/FOLR1 2 GO:0099174 regulation of presynapse organization 2/742 33/18722 0.378233104689563 0.591814139044172 APP/EIF4G1 2 GO:1901099 negative regulation of signal transduction in absence of ligand 2/742 33/18722 0.378233104689563 0.591814139044172 HSPA1A/HSPA1B 2 GO:1901380 negative regulation of potassium ion transmembrane transport 2/742 33/18722 0.378233104689563 0.591814139044172 CAV1/ANK3 2 GO:1902275 regulation of chromatin organization 2/742 33/18722 0.378233104689563 0.591814139044172 MPHOSPH8/TPR 2 GO:1902692 regulation of neuroblast proliferation 2/742 33/18722 0.378233104689563 0.591814139044172 GLI3/NF1 2 GO:1902992 negative regulation of amyloid precursor protein catabolic process 2/742 33/18722 0.378233104689563 0.591814139044172 RTN4/ROCK1 2 GO:1903146 regulation of autophagy of mitochondrion 2/742 33/18722 0.378233104689563 0.591814139044172 VPS13C/VDAC1 2 GO:1904031 positive regulation of cyclin-dependent protein kinase activity 2/742 33/18722 0.378233104689563 0.591814139044172 EGFR/CKS1B 2 GO:1905606 regulation of presynapse assembly 2/742 33/18722 0.378233104689563 0.591814139044172 APP/EIF4G1 2 GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 2/742 33/18722 0.378233104689563 0.591814139044172 HSPA1A/HSPA1B 2 GO:0010522 regulation of calcium ion transport into cytosol 5/742 102/18722 0.379613223550307 0.591814139044172 CAV1/GSTO1/DIAPH1/CALM1/CALM2 5 GO:1902749 regulation of cell cycle G2/M phase transition 5/742 102/18722 0.379613223550307 0.591814139044172 APP/PBX1/NPM1/BRD4/RAB11A 5 GO:0050804 modulation of chemical synaptic transmission 19/742 439/18722 0.379786455691643 0.591814139044172 EGFR/AKAP9/CDH1/APP/ITGB1/SLC6A4/MME/KIF5B/LGMN/NCSTN/PTPRA/PPP1R9A/SYT7/VAMP2/ERC1/EIF2AK4/CALM1/CLN3/RAB11A 19 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 4/742 79/18722 0.382695486535288 0.591814139044172 FLT1/IGF1R/MYDGF/ERBB3 4 GO:0051279 regulation of release of sequestered calcium ion into cytosol 4/742 79/18722 0.382695486535288 0.591814139044172 GSTO1/DIAPH1/CALM1/CALM2 4 GO:1901184 regulation of ERBB signaling pathway 4/742 79/18722 0.382695486535288 0.591814139044172 EGFR/RTN4/LGMN/PTPN12 4 GO:0099177 regulation of trans-synaptic signaling 19/742 440/18722 0.38357615913362 0.591814139044172 EGFR/AKAP9/CDH1/APP/ITGB1/SLC6A4/MME/KIF5B/LGMN/NCSTN/PTPRA/PPP1R9A/SYT7/VAMP2/ERC1/EIF2AK4/CALM1/CLN3/RAB11A 19 GO:0002711 positive regulation of T cell mediated immunity 3/742 56/18722 0.383728760513965 0.591814139044172 CD81/CD55/GATA3 3 GO:0006687 glycosphingolipid metabolic process 3/742 56/18722 0.383728760513965 0.591814139044172 HEXA/GLB1/HEXB 3 GO:0010518 positive regulation of phospholipase activity 3/742 56/18722 0.383728760513965 0.591814139044172 EGFR/FLT1/GNAQ 3 GO:0015800 acidic amino acid transport 3/742 56/18722 0.383728760513965 0.591814139044172 ITGB1/GJA1/ARL6IP5 3 GO:0042733 embryonic digit morphogenesis 3/742 56/18722 0.383728760513965 0.591814139044172 LRP5/GLI3/TMEM107 3 GO:0045599 negative regulation of fat cell differentiation 3/742 56/18722 0.383728760513965 0.591814139044172 ANKRD26/DDIT3/GATA3 3 GO:0055078 sodium ion homeostasis 3/742 56/18722 0.383728760513965 0.591814139044172 SLC9A1/ATP1A1/ATP6V1B1 3 GO:0090175 regulation of establishment of planar polarity 3/742 56/18722 0.383728760513965 0.591814139044172 ZNRF3/CDC42/RHOA 3 GO:0000012 single strand break repair 1/742 12/18722 0.384559389945707 0.591814139044172 PARP1 1 GO:0002024 diet induced thermogenesis 1/742 12/18722 0.384559389945707 0.591814139044172 ADRB1 1 GO:0002674 negative regulation of acute inflammatory response 1/742 12/18722 0.384559389945707 0.591814139044172 ASH1L 1 GO:0002863 positive regulation of inflammatory response to antigenic stimulus 1/742 12/18722 0.384559389945707 0.591814139044172 CD81 1 GO:0003207 cardiac chamber formation 1/742 12/18722 0.384559389945707 0.591814139044172 SOX4 1 GO:0006563 L-serine metabolic process 1/742 12/18722 0.384559389945707 0.591814139044172 SERINC3 1 GO:0006787 porphyrin-containing compound catabolic process 1/742 12/18722 0.384559389945707 0.591814139044172 BLVRA 1 GO:0007320 insemination 1/742 12/18722 0.384559389945707 0.591814139044172 SLC6A4 1 GO:0007614 short-term memory 1/742 12/18722 0.384559389945707 0.591814139044172 SERPINF1 1 GO:0009086 methionine biosynthetic process 1/742 12/18722 0.384559389945707 0.591814139044172 MTR 1 GO:0010454 negative regulation of cell fate commitment 1/742 12/18722 0.384559389945707 0.591814139044172 HES1 1 GO:0010587 miRNA catabolic process 1/742 12/18722 0.384559389945707 0.591814139044172 KCNQ1OT1 1 GO:0010623 programmed cell death involved in cell development 1/742 12/18722 0.384559389945707 0.591814139044172 PRKDC 1 GO:0010826 negative regulation of centrosome duplication 1/742 12/18722 0.384559389945707 0.591814139044172 NPM1 1 GO:0015780 nucleotide-sugar transmembrane transport 1/742 12/18722 0.384559389945707 0.591814139044172 SLC35B4 1 GO:0016554 cytidine to uridine editing 1/742 12/18722 0.384559389945707 0.591814139044172 RBM47 1 GO:0021527 spinal cord association neuron differentiation 1/742 12/18722 0.384559389945707 0.591814139044172 LMO4 1 GO:0021670 lateral ventricle development 1/742 12/18722 0.384559389945707 0.591814139044172 CDK6 1 GO:0021936 regulation of cerebellar granule cell precursor proliferation 1/742 12/18722 0.384559389945707 0.591814139044172 SLC6A4 1 GO:0030238 male sex determination 1/742 12/18722 0.384559389945707 0.591814139044172 SF1 1 GO:0030397 membrane disassembly 1/742 12/18722 0.384559389945707 0.591814139044172 NEK6 1 GO:0031953 negative regulation of protein autophosphorylation 1/742 12/18722 0.384559389945707 0.591814139044172 CAV1 1 GO:0032736 positive regulation of interleukin-13 production 1/742 12/18722 0.384559389945707 0.591814139044172 GATA3 1 GO:0032780 negative regulation of ATPase activity 1/742 12/18722 0.384559389945707 0.591814139044172 CNN3 1 GO:0032908 regulation of transforming growth factor beta1 production 1/742 12/18722 0.384559389945707 0.591814139044172 ATP6AP2 1 GO:0033015 tetrapyrrole catabolic process 1/742 12/18722 0.384559389945707 0.591814139044172 BLVRA 1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 1/742 12/18722 0.384559389945707 0.591814139044172 CROT 1 GO:0033629 negative regulation of cell adhesion mediated by integrin 1/742 12/18722 0.384559389945707 0.591814139044172 JAM3 1 GO:0035112 genitalia morphogenesis 1/742 12/18722 0.384559389945707 0.591814139044172 NIPBL 1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway 1/742 12/18722 0.384559389945707 0.591814139044172 COL4A2 1 GO:0038180 nerve growth factor signaling pathway 1/742 12/18722 0.384559389945707 0.591814139044172 KIDINS220 1 GO:0042117 monocyte activation 1/742 12/18722 0.384559389945707 0.591814139044172 FOXP1 1 GO:0043129 surfactant homeostasis 1/742 12/18722 0.384559389945707 0.591814139044172 EPAS1 1 GO:0043248 proteasome assembly 1/742 12/18722 0.384559389945707 0.591814139044172 POMP 1 GO:0043380 regulation of memory T cell differentiation 1/742 12/18722 0.384559389945707 0.591814139044172 CD46 1 GO:0043383 negative T cell selection 1/742 12/18722 0.384559389945707 0.591814139044172 GLI3 1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 1/742 12/18722 0.384559389945707 0.591814139044172 PHIP 1 GO:0044650 adhesion of symbiont to host cell 1/742 12/18722 0.384559389945707 0.591814139044172 CD81 1 GO:0045117 azole transmembrane transport 1/742 12/18722 0.384559389945707 0.591814139044172 SLC19A3 1 GO:0045602 negative regulation of endothelial cell differentiation 1/742 12/18722 0.384559389945707 0.591814139044172 ID1 1 GO:0046051 UTP metabolic process 1/742 12/18722 0.384559389945707 0.591814139044172 NME3 1 GO:0046322 negative regulation of fatty acid oxidation 1/742 12/18722 0.384559389945707 0.591814139044172 ACADVL 1 GO:0046541 saliva secretion 1/742 12/18722 0.384559389945707 0.591814139044172 KCNN4 1 GO:0046606 negative regulation of centrosome cycle 1/742 12/18722 0.384559389945707 0.591814139044172 NPM1 1 GO:0046831 regulation of RNA export from nucleus 1/742 12/18722 0.384559389945707 0.591814139044172 TPR 1 GO:0048934 peripheral nervous system neuron differentiation 1/742 12/18722 0.384559389945707 0.591814139044172 ISL1 1 GO:0048935 peripheral nervous system neuron development 1/742 12/18722 0.384559389945707 0.591814139044172 ISL1 1 GO:0051340 regulation of ligase activity 1/742 12/18722 0.384559389945707 0.591814139044172 TMSB4X 1 GO:0060009 Sertoli cell development 1/742 12/18722 0.384559389945707 0.591814139044172 ATRX 1 GO:0060221 retinal rod cell differentiation 1/742 12/18722 0.384559389945707 0.591814139044172 NAGLU 1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 1/742 12/18722 0.384559389945707 0.591814139044172 LRP1 1 GO:0060442 branching involved in prostate gland morphogenesis 1/742 12/18722 0.384559389945707 0.591814139044172 BMP7 1 GO:0060601 lateral sprouting from an epithelium 1/742 12/18722 0.384559389945707 0.591814139044172 BMP7 1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1/742 12/18722 0.384559389945707 0.591814139044172 GLI3 1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development 1/742 12/18722 0.384559389945707 0.591814139044172 YY1 1 GO:0061430 bone trabecula morphogenesis 1/742 12/18722 0.384559389945707 0.591814139044172 FBN2 1 GO:0061620 glycolytic process through glucose-6-phosphate 1/742 12/18722 0.384559389945707 0.591814139044172 ENO1 1 GO:0070202 regulation of establishment of protein localization to chromosome 1/742 12/18722 0.384559389945707 0.591814139044172 CCT3 1 GO:0070213 protein auto-ADP-ribosylation 1/742 12/18722 0.384559389945707 0.591814139044172 PARP1 1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain 1/742 12/18722 0.384559389945707 0.591814139044172 BRD4 1 GO:0071107 response to parathyroid hormone 1/742 12/18722 0.384559389945707 0.591814139044172 GJA1 1 GO:0071257 cellular response to electrical stimulus 1/742 12/18722 0.384559389945707 0.591814139044172 SLC9A1 1 GO:0071468 cellular response to acidic pH 1/742 12/18722 0.384559389945707 0.591814139044172 SLC9A1 1 GO:0072015 glomerular visceral epithelial cell development 1/742 12/18722 0.384559389945707 0.591814139044172 IQGAP1 1 GO:0072182 regulation of nephron tubule epithelial cell differentiation 1/742 12/18722 0.384559389945707 0.591814139044172 GATA3 1 GO:0072376 protein activation cascade 1/742 12/18722 0.384559389945707 0.591814139044172 FBLN1 1 GO:0072711 cellular response to hydroxyurea 1/742 12/18722 0.384559389945707 0.591814139044172 ATRX 1 GO:0086067 AV node cell to bundle of His cell communication 1/742 12/18722 0.384559389945707 0.591814139044172 GJA5 1 GO:0097152 mesenchymal cell apoptotic process 1/742 12/18722 0.384559389945707 0.591814139044172 BMP7 1 GO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus 1/742 12/18722 0.384559389945707 0.591814139044172 MIA3 1 GO:0150065 regulation of deacetylase activity 1/742 12/18722 0.384559389945707 0.591814139044172 KDM5A 1 GO:1901298 regulation of hydrogen peroxide-mediated programmed cell death 1/742 12/18722 0.384559389945707 0.591814139044172 MET 1 GO:1901894 regulation of ATPase-coupled calcium transmembrane transporter activity 1/742 12/18722 0.384559389945707 0.591814139044172 C4orf3 1 GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance 1/742 12/18722 0.384559389945707 0.591814139044172 NRP1 1 GO:1902563 regulation of neutrophil activation 1/742 12/18722 0.384559389945707 0.591814139044172 GRN 1 GO:1903405 protein localization to nuclear body 1/742 12/18722 0.384559389945707 0.591814139044172 CCT3 1 GO:1903599 positive regulation of autophagy of mitochondrion 1/742 12/18722 0.384559389945707 0.591814139044172 VDAC1 1 GO:1903909 regulation of receptor clustering 1/742 12/18722 0.384559389945707 0.591814139044172 CD81 1 GO:1904748 regulation of apoptotic process involved in development 1/742 12/18722 0.384559389945707 0.591814139044172 BMP7 1 GO:1904816 positive regulation of protein localization to chromosome, telomeric region 1/742 12/18722 0.384559389945707 0.591814139044172 CCT3 1 GO:1904867 protein localization to Cajal body 1/742 12/18722 0.384559389945707 0.591814139044172 CCT3 1 GO:1905205 positive regulation of connective tissue replacement 1/742 12/18722 0.384559389945707 0.591814139044172 ROCK1 1 GO:1905214 regulation of RNA binding 1/742 12/18722 0.384559389945707 0.591814139044172 EIF4G1 1 GO:1905245 regulation of aspartic-type peptidase activity 1/742 12/18722 0.384559389945707 0.591814139044172 GRN 1 GO:1905709 negative regulation of membrane permeability 1/742 12/18722 0.384559389945707 0.591814139044172 DYNLT1 1 GO:2000009 negative regulation of protein localization to cell surface 1/742 12/18722 0.384559389945707 0.591814139044172 LEPROT 1 GO:2000105 positive regulation of DNA-dependent DNA replication 1/742 12/18722 0.384559389945707 0.591814139044172 ATRX 1 GO:2000303 regulation of ceramide biosynthetic process 1/742 12/18722 0.384559389945707 0.591814139044172 ORMDL1 1 GO:2000508 regulation of dendritic cell chemotaxis 1/742 12/18722 0.384559389945707 0.591814139044172 CALR 1 GO:2000628 regulation of miRNA metabolic process 1/742 12/18722 0.384559389945707 0.591814139044172 KCNQ1OT1 1 GO:2001214 positive regulation of vasculogenesis 1/742 12/18722 0.384559389945707 0.591814139044172 ADM 1 GO:0072521 purine-containing compound metabolic process 18/742 416/18722 0.385098496055898 0.592459224701382 GAPDH/SLC26A2/APP/LDHA/ALDOA/ACSS1/TPST2/TMSB4X/TPI1/CROT/ENO1/DLG1/NCOR1/NME3/PKM/PARP1/RAN/RHOA 18 GO:0045619 regulation of lymphocyte differentiation 8/742 174/18722 0.385362770260146 0.592681222006576 CD46/SOX4/PRKDC/ZFP36L1/ANXA1/GLI3/GATA3/RHOA 8 GO:0007204 positive regulation of cytosolic calcium ion concentration 14/742 319/18722 0.386548958746352 0.594320527920006 LRP1/ITGAV/CAV1/GJA1/GSTO1/ATP2B4/DIAPH1/CD55/ADM/DDIT3/CALM1/BCAP31/TGM2/CALM2 14 GO:0030148 sphingolipid biosynthetic process 5/742 103/18722 0.387532254977896 0.595646963158309 ORMDL1/HACD3/PLPP3/DEGS1/ASAH1 5 GO:0048565 digestive tract development 6/742 127/18722 0.389978626378379 0.59922065763894 EGFR/LGR4/IL6ST/GLI3/NIPBL/HES1 6 GO:2000181 negative regulation of blood vessel morphogenesis 7/742 151/18722 0.391098969544462 0.599673637989511 SEMA6A/SERPINF1/COL4A2/ADAMTS1/ATP2B4/ROCK1/GTF2I 7 GO:0000038 very long-chain fatty acid metabolic process 2/742 34/18722 0.392458476036456 0.599673637989511 SLC27A2/HACD3 2 GO:0006270 DNA replication initiation 2/742 34/18722 0.392458476036456 0.599673637989511 PURA/CCNE1 2 GO:0009649 entrainment of circadian clock 2/742 34/18722 0.392458476036456 0.599673637989511 GNAQ/NR2F6 2 GO:0010614 negative regulation of cardiac muscle hypertrophy 2/742 34/18722 0.392458476036456 0.599673637989511 ATP2B4/YY1 2 GO:0019076 viral release from host cell 2/742 34/18722 0.392458476036456 0.599673637989511 DDB1/PPIA 2 GO:0032212 positive regulation of telomere maintenance via telomerase 2/742 34/18722 0.392458476036456 0.599673637989511 HNRNPA1/CCT3 2 GO:0032743 positive regulation of interleukin-2 production 2/742 34/18722 0.392458476036456 0.599673637989511 SPTBN1/ANXA1 2 GO:0032770 positive regulation of monooxygenase activity 2/742 34/18722 0.392458476036456 0.599673637989511 POR/CALM1 2 GO:0035890 exit from host 2/742 34/18722 0.392458476036456 0.599673637989511 DDB1/PPIA 2 GO:0035891 exit from host cell 2/742 34/18722 0.392458476036456 0.599673637989511 DDB1/PPIA 2 GO:0043276 anoikis 2/742 34/18722 0.392458476036456 0.599673637989511 ITGB1/CAV1 2 GO:0044319 wound healing, spreading of cells 2/742 34/18722 0.392458476036456 0.599673637989511 FERMT1/RHOA 2 GO:0048741 skeletal muscle fiber development 2/742 34/18722 0.392458476036456 0.599673637989511 PLEC/GPX1 2 GO:0048854 brain morphogenesis 2/742 34/18722 0.392458476036456 0.599673637989511 SLC6A4/NF1 2 GO:0086019 cell-cell signaling involved in cardiac conduction 2/742 34/18722 0.392458476036456 0.599673637989511 GJA1/GJA5 2 GO:0090505 epiboly involved in wound healing 2/742 34/18722 0.392458476036456 0.599673637989511 FERMT1/RHOA 2 GO:1904893 negative regulation of receptor signaling pathway via STAT 2/742 34/18722 0.392458476036456 0.599673637989511 CAV1/LEPROT 2 GO:0006695 cholesterol biosynthetic process 3/742 57/18722 0.394543113049859 0.602113987786933 DHCR24/POR/MBTPS1 3 GO:0034205 amyloid-beta formation 3/742 57/18722 0.394543113049859 0.602113987786933 RTN4/NCSTN/ROCK1 3 GO:0060760 positive regulation of response to cytokine stimulus 3/742 57/18722 0.394543113049859 0.602113987786933 HSPA1A/TRIM44/HSPA1B 3 GO:1902653 secondary alcohol biosynthetic process 3/742 57/18722 0.394543113049859 0.602113987786933 DHCR24/POR/MBTPS1 3 GO:0016573 histone acetylation 7/742 152/18722 0.397621235754928 0.602174212975514 ISL1/NCOA3/BRD7/GATA3/USP22/PHF20/MORF4L2 7 GO:1901343 negative regulation of vasculature development 7/742 152/18722 0.397621235754928 0.602174212975514 SEMA6A/SERPINF1/COL4A2/ADAMTS1/ATP2B4/ROCK1/GTF2I 7 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 12/742 273/18722 0.398562614657299 0.602174212975514 CDH1/ITGB1/CLDN4/TENM3/DSC3/BSG/CADM1/DSG2/DSC2/PTPRF/FAT1/OBSL1 12 GO:0000422 autophagy of mitochondrion 4/742 81/18722 0.400768279523781 0.602174212975514 VPS13C/RB1CC1/HUWE1/VDAC1 4 GO:0044773 mitotic DNA damage checkpoint signaling 4/742 81/18722 0.400768279523781 0.602174212975514 SOX4/RPL26/PRKDC/PPP1R10 4 GO:0046209 nitric oxide metabolic process 4/742 81/18722 0.400768279523781 0.602174212975514 CAV1/DYNLL1/ATP2B4/POR 4 GO:0061726 mitochondrion disassembly 4/742 81/18722 0.400768279523781 0.602174212975514 VPS13C/RB1CC1/HUWE1/VDAC1 4 GO:2000106 regulation of leukocyte apoptotic process 4/742 81/18722 0.400768279523781 0.602174212975514 SLC39A10/ANXA1/FOXP1/DOCK8 4 GO:2001021 negative regulation of response to DNA damage stimulus 4/742 81/18722 0.400768279523781 0.602174212975514 TPT1/MIF/PPP1R10/RIF1 4 GO:0006364 rRNA processing 10/742 225/18722 0.401357396252928 0.602174212975514 RPS21/RPS6/RPS16/RPL14/RPL7/RPS25/RPL26/PRKDC/DDX17/RPS17 10 GO:0006473 protein acetylation 9/742 201/18722 0.402552258383668 0.602174212975514 SOX4/ISL1/POR/NCOA3/BRD7/GATA3/USP22/PHF20/MORF4L2 9 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 5/742 105/18722 0.403348739598844 0.602174212975514 NRP1/PFN1/WASF2/CDC42/EPS8L1 5 GO:0006333 chromatin assembly or disassembly 8/742 177/18722 0.403520929385934 0.602174212975514 ATRX/NPM1/ARID1A/BRD2/HP1BP3/BAZ1B/RSF1/HMGA1 8 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 6/742 129/18722 0.404212014987106 0.602174212975514 CTSD/ARL6IP5/S100A9/PMAIP1/BCAP31/RHOA 6 GO:0002931 response to ischemia 3/742 58/18722 0.405306974202555 0.602174212975514 CAV1/GJA1/EGR1 3 GO:0000460 maturation of 5.8S rRNA 2/742 35/18722 0.4065345592267 0.602174212975514 RPS21/PRKDC 2 GO:0003298 physiological muscle hypertrophy 2/742 35/18722 0.4065345592267 0.602174212975514 AKAP13/YY1 2 GO:0003301 physiological cardiac muscle hypertrophy 2/742 35/18722 0.4065345592267 0.602174212975514 AKAP13/YY1 2 GO:0010664 negative regulation of striated muscle cell apoptotic process 2/742 35/18722 0.4065345592267 0.602174212975514 PPP1R10/BMP7 2 GO:0010837 regulation of keratinocyte proliferation 2/742 35/18722 0.4065345592267 0.602174212975514 ZFP36L1/SRSF6 2 GO:0031076 embryonic camera-type eye development 2/742 35/18722 0.4065345592267 0.602174212975514 BMP7/CITED2 2 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 2/742 35/18722 0.4065345592267 0.602174212975514 EIF3H/SDCBP 2 GO:0033280 response to vitamin D 2/742 35/18722 0.4065345592267 0.602174212975514 ATP2B1/BMP7 2 GO:0042462 eye photoreceptor cell development 2/742 35/18722 0.4065345592267 0.602174212975514 NAGLU/TUG1 2 GO:0044273 sulfur compound catabolic process 2/742 35/18722 0.4065345592267 0.602174212975514 GNS/GLB1 2 GO:0045880 positive regulation of smoothened signaling pathway 2/742 35/18722 0.4065345592267 0.602174212975514 DLG5/POR 2 GO:0045922 negative regulation of fatty acid metabolic process 2/742 35/18722 0.4065345592267 0.602174212975514 NCOR1/ACADVL 2 GO:0046640 regulation of alpha-beta T cell proliferation 2/742 35/18722 0.4065345592267 0.602174212975514 CD81/CD55 2 GO:0048821 erythrocyte development 2/742 35/18722 0.4065345592267 0.602174212975514 RPS6/CITED2 2 GO:0050654 chondroitin sulfate proteoglycan metabolic process 2/742 35/18722 0.4065345592267 0.602174212975514 CHPF/B3GAT3 2 GO:0061049 cell growth involved in cardiac muscle cell development 2/742 35/18722 0.4065345592267 0.602174212975514 AKAP13/YY1 2 GO:0071108 protein K48-linked deubiquitination 2/742 35/18722 0.4065345592267 0.602174212975514 USP9X/USP27X 2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 2/742 35/18722 0.4065345592267 0.602174212975514 NRP1/ANXA1 2 GO:0090504 epiboly 2/742 35/18722 0.4065345592267 0.602174212975514 FERMT1/RHOA 2 GO:0098801 regulation of renal system process 2/742 35/18722 0.4065345592267 0.602174212975514 GJA1/GJA5 2 GO:0098810 neurotransmitter reuptake 2/742 35/18722 0.4065345592267 0.602174212975514 ITGB1/SLC6A4 2 GO:1905207 regulation of cardiocyte differentiation 2/742 35/18722 0.4065345592267 0.602174212975514 EGFR/DHX36 2 GO:0002703 regulation of leukocyte mediated immunity 10/742 226/18722 0.406716633501277 0.602174212975514 CD46/CADM1/TFRC/CD81/CD55/LAMP1/DHX36/RIF1/GATA3/SERPINB9 10 GO:0043087 regulation of GTPase activity 15/742 348/18722 0.406822500496205 0.602174212975514 ITGB1/ITGA6/IQGAP2/MET/IQGAP1/NF1/CCPG1/ADRB1/RASA1/SYDE2/RABGAP1/DOCK8/S100A10/TGM2/DYNLT1 15 GO:0019722 calcium-mediated signaling 9/742 202/18722 0.408227798196015 0.602174212975514 EGFR/GSTO1/ATP2B4/NFAT5/SLC9A1/PPP1R9A/CALM1/BCAP31/CALM2 9 GO:0001682 tRNA 5'-leader removal 1/742 13/18722 0.408966494844707 0.602174212975514 SSB 1 GO:0001768 establishment of T cell polarity 1/742 13/18722 0.408966494844707 0.602174212975514 DOCK8 1 GO:0001778 plasma membrane repair 1/742 13/18722 0.408966494844707 0.602174212975514 SYT7 1 GO:0001886 endothelial cell morphogenesis 1/742 13/18722 0.408966494844707 0.602174212975514 MET 1 GO:0002638 negative regulation of immunoglobulin production 1/742 13/18722 0.408966494844707 0.602174212975514 PRKDC 1 GO:0003334 keratinocyte development 1/742 13/18722 0.408966494844707 0.602174212975514 PLEC 1 GO:0006000 fructose metabolic process 1/742 13/18722 0.408966494844707 0.602174212975514 ALDOA 1 GO:0007183 SMAD protein complex assembly 1/742 13/18722 0.408966494844707 0.602174212975514 PARP1 1 GO:0007494 midgut development 1/742 13/18722 0.408966494844707 0.602174212975514 EGFR 1 GO:0007567 parturition 1/742 13/18722 0.408966494844707 0.602174212975514 HPGD 1 GO:0010755 regulation of plasminogen activation 1/742 13/18722 0.408966494844707 0.602174212975514 ENO1 1 GO:0014745 negative regulation of muscle adaptation 1/742 13/18722 0.408966494844707 0.602174212975514 ATP2B4 1 GO:0015791 polyol transport 1/742 13/18722 0.408966494844707 0.602174212975514 SLC5A3 1 GO:0015801 aromatic amino acid transport 1/742 13/18722 0.408966494844707 0.602174212975514 SLC3A2 1 GO:0016024 CDP-diacylglycerol biosynthetic process 1/742 13/18722 0.408966494844707 0.602174212975514 CDS1 1 GO:0016056 rhodopsin mediated signaling pathway 1/742 13/18722 0.408966494844707 0.602174212975514 NMT1 1 GO:0016322 neuron remodeling 1/742 13/18722 0.408966494844707 0.602174212975514 APP 1 GO:0021984 adenohypophysis development 1/742 13/18722 0.408966494844707 0.602174212975514 HES1 1 GO:0030497 fatty acid elongation 1/742 13/18722 0.408966494844707 0.602174212975514 HACD3 1 GO:0030836 positive regulation of actin filament depolymerization 1/742 13/18722 0.408966494844707 0.602174212975514 DSTN 1 GO:0031272 regulation of pseudopodium assembly 1/742 13/18722 0.408966494844707 0.602174212975514 CDC42 1 GO:0031274 positive regulation of pseudopodium assembly 1/742 13/18722 0.408966494844707 0.602174212975514 CDC42 1 GO:0031392 regulation of prostaglandin biosynthetic process 1/742 13/18722 0.408966494844707 0.602174212975514 ANXA1 1 GO:0032042 mitochondrial DNA metabolic process 1/742 13/18722 0.408966494844707 0.602174212975514 PARP1 1 GO:0032230 positive regulation of synaptic transmission, GABAergic 1/742 13/18722 0.408966494844707 0.602174212975514 KIF5B 1 GO:0032252 secretory granule localization 1/742 13/18722 0.408966494844707 0.602174212975514 KIF5B 1 GO:0032905 transforming growth factor beta1 production 1/742 13/18722 0.408966494844707 0.602174212975514 ATP6AP2 1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter 1/742 13/18722 0.408966494844707 0.602174212975514 BRD4 1 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway 1/742 13/18722 0.408966494844707 0.602174212975514 PARP1 1 GO:0033262 regulation of nuclear cell cycle DNA replication 1/742 13/18722 0.408966494844707 0.602174212975514 ATRX 1 GO:0033689 negative regulation of osteoblast proliferation 1/742 13/18722 0.408966494844707 0.602174212975514 ATRAID 1 GO:0034982 mitochondrial protein processing 1/742 13/18722 0.408966494844707 0.602174212975514 YME1L1 1 GO:0035331 negative regulation of hippo signaling 1/742 13/18722 0.408966494844707 0.602174212975514 DLG5 1 GO:0036462 TRAIL-activated apoptotic signaling pathway 1/742 13/18722 0.408966494844707 0.602174212975514 TIMP3 1 GO:0042308 negative regulation of protein import into nucleus 1/742 13/18722 0.408966494844707 0.602174212975514 FERMT1 1 GO:0042492 gamma-delta T cell differentiation 1/742 13/18722 0.408966494844707 0.602174212975514 SOX4 1 GO:0042538 hyperosmotic salinity response 1/742 13/18722 0.408966494844707 0.602174212975514 EFHD1 1 GO:0042659 regulation of cell fate specification 1/742 13/18722 0.408966494844707 0.602174212975514 LMO4 1 GO:0042761 very long-chain fatty acid biosynthetic process 1/742 13/18722 0.408966494844707 0.602174212975514 HACD3 1 GO:0043247 telomere maintenance in response to DNA damage 1/742 13/18722 0.408966494844707 0.602174212975514 RIF1 1 GO:0043379 memory T cell differentiation 1/742 13/18722 0.408966494844707 0.602174212975514 CD46 1 GO:0043970 histone H3-K9 acetylation 1/742 13/18722 0.408966494844707 0.602174212975514 GATA3 1 GO:0044090 positive regulation of vacuole organization 1/742 13/18722 0.408966494844707 0.602174212975514 GRN 1 GO:0046415 urate metabolic process 1/742 13/18722 0.408966494844707 0.602174212975514 SLC22A11 1 GO:0046512 sphingosine biosynthetic process 1/742 13/18722 0.408966494844707 0.602174212975514 ASAH1 1 GO:0046520 sphingoid biosynthetic process 1/742 13/18722 0.408966494844707 0.602174212975514 ASAH1 1 GO:0046689 response to mercury ion 1/742 13/18722 0.408966494844707 0.602174212975514 BSG 1 GO:0048266 behavioral response to pain 1/742 13/18722 0.408966494844707 0.602174212975514 VWA1 1 GO:0048820 hair follicle maturation 1/742 13/18722 0.408966494844707 0.602174212975514 FERMT1 1 GO:0051709 regulation of killing of cells of other organism 1/742 13/18722 0.408966494844707 0.602174212975514 SERPINB9 1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore 1/742 13/18722 0.408966494844707 0.602174212975514 CDC42 1 GO:0061615 glycolytic process through fructose-6-phosphate 1/742 13/18722 0.408966494844707 0.602174212975514 ENO1 1 GO:0061744 motor behavior 1/742 13/18722 0.408966494844707 0.602174212975514 DPP4 1 GO:0070254 mucus secretion 1/742 13/18722 0.408966494844707 0.602174212975514 EGFR 1 GO:0070914 UV-damage excision repair 1/742 13/18722 0.408966494844707 0.602174212975514 DDB1 1 GO:0071696 ectodermal placode development 1/742 13/18722 0.408966494844707 0.602174212975514 NRP1 1 GO:0071801 regulation of podosome assembly 1/742 13/18722 0.408966494844707 0.602174212975514 RHOA 1 GO:0072310 glomerular epithelial cell development 1/742 13/18722 0.408966494844707 0.602174212975514 IQGAP1 1 GO:0072393 microtubule anchoring at microtubule organizing center 1/742 13/18722 0.408966494844707 0.602174212975514 PCM1 1 GO:0072710 response to hydroxyurea 1/742 13/18722 0.408966494844707 0.602174212975514 ATRX 1 GO:0090153 regulation of sphingolipid biosynthetic process 1/742 13/18722 0.408966494844707 0.602174212975514 ORMDL1 1 GO:0090158 endoplasmic reticulum membrane organization 1/742 13/18722 0.408966494844707 0.602174212975514 RTN4 1 GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 1/742 13/18722 0.408966494844707 0.602174212975514 ATP2B4 1 GO:0106074 aminoacyl-tRNA metabolism involved in translational fidelity 1/742 13/18722 0.408966494844707 0.602174212975514 IARS2 1 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response 1/742 13/18722 0.408966494844707 0.602174212975514 ATF6 1 GO:1900121 negative regulation of receptor binding 1/742 13/18722 0.408966494844707 0.602174212975514 PTPRF 1 GO:1900452 regulation of long-term synaptic depression 1/742 13/18722 0.408966494844707 0.602174212975514 PPP1R9A 1 GO:1901096 regulation of autophagosome maturation 1/742 13/18722 0.408966494844707 0.602174212975514 CLN3 1 GO:1902260 negative regulation of delayed rectifier potassium channel activity 1/742 13/18722 0.408966494844707 0.602174212975514 ANK3 1 GO:1902947 regulation of tau-protein kinase activity 1/742 13/18722 0.408966494844707 0.602174212975514 EGR1 1 GO:1903977 positive regulation of glial cell migration 1/742 13/18722 0.408966494844707 0.602174212975514 LRP1 1 GO:1904590 negative regulation of protein import 1/742 13/18722 0.408966494844707 0.602174212975514 FERMT1 1 GO:1905038 regulation of membrane lipid metabolic process 1/742 13/18722 0.408966494844707 0.602174212975514 ORMDL1 1 GO:1905064 negative regulation of vascular associated smooth muscle cell differentiation 1/742 13/18722 0.408966494844707 0.602174212975514 PDCD4 1 GO:1905203 regulation of connective tissue replacement 1/742 13/18722 0.408966494844707 0.602174212975514 ROCK1 1 GO:1905939 regulation of gonad development 1/742 13/18722 0.408966494844707 0.602174212975514 CITED2 1 GO:1990403 embryonic brain development 1/742 13/18722 0.408966494844707 0.602174212975514 TRA2B 1 GO:2001023 regulation of response to drug 1/742 13/18722 0.408966494844707 0.602174212975514 ADIRF 1 GO:0048015 phosphatidylinositol-mediated signaling 8/742 178/18722 0.409575165325957 0.602281583216519 EGFR/ZFP36L1/FLT1/IGF1R/NF1/MYDGF/ERBB3/GATA3 8 GO:0016575 histone deacetylation 4/742 82/18722 0.409770931415126 0.602281583216519 KDM5A/NIPBL/TBL1X/MORF4L2 4 GO:0043242 negative regulation of protein-containing complex disassembly 4/742 82/18722 0.409770931415126 0.602281583216519 SPTAN1/SPTBN1/TRIOBP/CAPZB 4 GO:0046364 monosaccharide biosynthetic process 4/742 82/18722 0.409770931415126 0.602281583216519 TPI1/DDB1/RANBP2/SLC35B4 4 GO:0046889 positive regulation of lipid biosynthetic process 4/742 82/18722 0.409770931415126 0.602281583216519 POR/ANXA1/ADM/CGA 4 GO:2001057 reactive nitrogen species metabolic process 4/742 82/18722 0.409770931415126 0.602281583216519 CAV1/DYNLL1/ATP2B4/POR 4 GO:0006869 lipid transport 17/742 398/18722 0.41083555977188 0.603666765399491 LRP1/ITGAV/SLC2A1/PSAP/KCNN4/CAV1/SLC27A2/ANXA1/CROT/LRP10/PLIN2/ATP10D/SYT7/KDM5B/NFKBIA/CLN3/CYP19A1 17 GO:0016050 vesicle organization 13/742 300/18722 0.411011210557825 0.603745281045393 CAV1/TMED9/EEA1/HOOK2/MIA3/ANXA1/KIF5B/SYT7/VAMP2/CLN3/S100A10/RAB11A/SDCBP 13 GO:0019882 antigen processing and presentation 5/742 106/18722 0.411240096629933 0.603901925491043 CTSL/CTSD/CTSV/CALR/LGMN 5 GO:0007416 synapse assembly 8/742 179/18722 0.415627789870061 0.610163828219346 CDH1/APP/DLG5/EIF4G1/PPP1R9A/TPBG/OBSL1/SDCBP 8 GO:0001836 release of cytochrome c from mitochondria 3/742 59/18722 0.416013843277667 0.610186575353823 JUN/PMAIP1/GPX1 3 GO:0048010 vascular endothelial growth factor receptor signaling pathway 3/742 59/18722 0.416013843277667 0.610186575353823 FLT1/NRP1/HSPB1 3 GO:0051055 negative regulation of lipid biosynthetic process 3/742 59/18722 0.416013843277667 0.610186575353823 ORMDL1/ATP1A1/ACADVL 3 GO:0043367 CD4-positive, alpha-beta T cell differentiation 4/742 83/18722 0.418745485172545 0.614010892476216 CTSL/ANXA1/FOXP1/GATA3 4 GO:0000018 regulation of DNA recombination 5/742 107/18722 0.419116251376661 0.614189938238121 FUS/TFRC/RIF1/RAD50/PARP1 5 GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 5/742 107/18722 0.419116251376661 0.614189938238121 TFRC/CD81/CD55/RIF1/GATA3 5 GO:0003203 endocardial cushion morphogenesis 2/742 36/18722 0.420450841504624 0.614686936085481 BMP7/ISL1 2 GO:0014741 negative regulation of muscle hypertrophy 2/742 36/18722 0.420450841504624 0.614686936085481 ATP2B4/YY1 2 GO:0042119 neutrophil activation 2/742 36/18722 0.420450841504624 0.614686936085481 GRN/ANXA3 2 GO:0045191 regulation of isotype switching 2/742 36/18722 0.420450841504624 0.614686936085481 TFRC/RIF1 2 GO:0045746 negative regulation of Notch signaling pathway 2/742 36/18722 0.420450841504624 0.614686936085481 BMP7/NFKBIA 2 GO:0051354 negative regulation of oxidoreductase activity 2/742 36/18722 0.420450841504624 0.614686936085481 CAV1/ATP2B4 2 GO:0090322 regulation of superoxide metabolic process 2/742 36/18722 0.420450841504624 0.614686936085481 EGFR/BMP7 2 GO:1901658 glycosyl compound catabolic process 2/742 36/18722 0.420450841504624 0.614686936085481 FUCA1/GUSB 2 GO:0071897 DNA biosynthetic process 8/742 180/18722 0.421677406506115 0.616297747970476 DUSP1/GJA1/HNRNPA1/RAD50/USP10/HNRNPC/PTGES3/CCT3 8 GO:0071695 anatomical structure maturation 10/742 229/18722 0.422798657364424 0.617753731848641 APP/DAG1/FERMT1/ATP6AP2/RERE/DDIT3/GATA3/EPAS1/HES1/RHOA 10 GO:0009620 response to fungus 3/742 60/18722 0.426657555582843 0.622403895891225 GAPDH/S100A9/COTL1 3 GO:0060038 cardiac muscle cell proliferation 3/742 60/18722 0.426657555582843 0.622403895891225 TGFBR3/GJA1/CITED2 3 GO:0022037 metencephalon development 5/742 108/18722 0.426974335716273 0.622403895891225 HSPA5/NAGLU/NCSTN/RERE/SDF4 5 GO:0032370 positive regulation of lipid transport 4/742 84/18722 0.427687917307692 0.622403895891225 LRP1/CAV1/NFKBIA/CYP19A1 4 GO:0097696 receptor signaling pathway via STAT 8/742 181/18722 0.427722636472974 0.622403895891225 CAV1/IL6ST/CSH1/ISL1/PRLR/IL10RB/LEPROT/HES1 8 GO:0000212 meiotic spindle organization 1/742 14/18722 0.432406917145483 0.622403895891225 ATRX 1 GO:0001711 endodermal cell fate commitment 1/742 14/18722 0.432406917145483 0.622403895891225 RTF1 1 GO:0001767 establishment of lymphocyte polarity 1/742 14/18722 0.432406917145483 0.622403895891225 DOCK8 1 GO:0002829 negative regulation of type 2 immune response 1/742 14/18722 0.432406917145483 0.622403895891225 ANXA1 1 GO:0003188 heart valve formation 1/742 14/18722 0.432406917145483 0.622403895891225 GJA5 1 GO:0006241 CTP biosynthetic process 1/742 14/18722 0.432406917145483 0.622403895891225 NME3 1 GO:0007100 mitotic centrosome separation 1/742 14/18722 0.432406917145483 0.622403895891225 RANBP1 1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity 1/742 14/18722 0.432406917145483 0.622403895891225 PRLR 1 GO:0009071 serine family amino acid catabolic process 1/742 14/18722 0.432406917145483 0.622403895891225 GLDC 1 GO:0010421 hydrogen peroxide-mediated programmed cell death 1/742 14/18722 0.432406917145483 0.622403895891225 MET 1 GO:0014874 response to stimulus involved in regulation of muscle adaptation 1/742 14/18722 0.432406917145483 0.622403895891225 DAG1 1 GO:0018158 protein oxidation 1/742 14/18722 0.432406917145483 0.622403895891225 GPX1 1 GO:0030007 cellular potassium ion homeostasis 1/742 14/18722 0.432406917145483 0.622403895891225 ATP1A1 1 GO:0030213 hyaluronan biosynthetic process 1/742 14/18722 0.432406917145483 0.622403895891225 CLTC 1 GO:0031054 pre-miRNA processing 1/742 14/18722 0.432406917145483 0.622403895891225 ADAR 1 GO:0032688 negative regulation of interferon-beta production 1/742 14/18722 0.432406917145483 0.622403895891225 YY1 1 GO:0035641 locomotory exploration behavior 1/742 14/18722 0.432406917145483 0.622403895891225 DPP4 1 GO:0035672 oligopeptide transmembrane transport 1/742 14/18722 0.432406917145483 0.622403895891225 GJA1 1 GO:0036444 calcium import into the mitochondrion 1/742 14/18722 0.432406917145483 0.622403895891225 VDAC1 1 GO:0043922 negative regulation by host of viral transcription 1/742 14/18722 0.432406917145483 0.622403895891225 JUN 1 GO:0044154 histone H3-K14 acetylation 1/742 14/18722 0.432406917145483 0.622403895891225 GATA3 1 GO:0045472 response to ether 1/742 14/18722 0.432406917145483 0.622403895891225 LARP1 1 GO:0045820 negative regulation of glycolytic process 1/742 14/18722 0.432406917145483 0.622403895891225 NCOR1 1 GO:0046341 CDP-diacylglycerol metabolic process 1/742 14/18722 0.432406917145483 0.622403895891225 CDS1 1 GO:0048172 regulation of short-term neuronal synaptic plasticity 1/742 14/18722 0.432406917145483 0.622403895891225 CLN3 1 GO:0048368 lateral mesoderm development 1/742 14/18722 0.432406917145483 0.622403895891225 CITED2 1 GO:0048875 chemical homeostasis within a tissue 1/742 14/18722 0.432406917145483 0.622403895891225 EPAS1 1 GO:0051589 negative regulation of neurotransmitter transport 1/742 14/18722 0.432406917145483 0.622403895891225 PPP1R9A 1 GO:0060081 membrane hyperpolarization 1/742 14/18722 0.432406917145483 0.622403895891225 ATP1A1 1 GO:0060088 auditory receptor cell stereocilium organization 1/742 14/18722 0.432406917145483 0.622403895891225 TRIOBP 1 GO:0060576 intestinal epithelial cell development 1/742 14/18722 0.432406917145483 0.622403895891225 IL6ST 1 GO:0060911 cardiac cell fate commitment 1/742 14/18722 0.432406917145483 0.622403895891225 ISL1 1 GO:0070986 left/right axis specification 1/742 14/18722 0.432406917145483 0.622403895891225 CITED2 1 GO:0072160 nephron tubule epithelial cell differentiation 1/742 14/18722 0.432406917145483 0.622403895891225 GATA3 1 GO:0072176 nephric duct development 1/742 14/18722 0.432406917145483 0.622403895891225 GATA3 1 GO:0072498 embryonic skeletal joint development 1/742 14/18722 0.432406917145483 0.622403895891225 BMP7 1 GO:0090281 negative regulation of calcium ion import 1/742 14/18722 0.432406917145483 0.622403895891225 VDAC1 1 GO:0090308 regulation of DNA methylation-dependent heterochromatin assembly 1/742 14/18722 0.432406917145483 0.622403895891225 MPHOSPH8 1 GO:0090715 immunological memory formation process 1/742 14/18722 0.432406917145483 0.622403895891225 CD46 1 GO:0099638 endosome to plasma membrane protein transport 1/742 14/18722 0.432406917145483 0.622403895891225 RAB11A 1 GO:1900037 regulation of cellular response to hypoxia 1/742 14/18722 0.432406917145483 0.622403895891225 ENO1 1 GO:1901857 positive regulation of cellular respiration 1/742 14/18722 0.432406917145483 0.622403895891225 IL10RB 1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/742 14/18722 0.432406917145483 0.622403895891225 MIF 1 GO:1904814 regulation of protein localization to chromosome, telomeric region 1/742 14/18722 0.432406917145483 0.622403895891225 CCT3 1 GO:1905208 negative regulation of cardiocyte differentiation 1/742 14/18722 0.432406917145483 0.622403895891225 EGFR 1 GO:1990173 protein localization to nucleoplasm 1/742 14/18722 0.432406917145483 0.622403895891225 CCT3 1 GO:0048017 inositol lipid-mediated signaling 8/742 182/18722 0.433762119400093 0.622623368553871 EGFR/ZFP36L1/FLT1/IGF1R/NF1/MYDGF/ERBB3/GATA3 8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2/742 37/18722 0.434197875438884 0.622623368553871 RPS21/RPS16 2 GO:0003176 aortic valve development 2/742 37/18722 0.434197875438884 0.622623368553871 ROCK1/GATA3 2 GO:0014904 myotube cell development 2/742 37/18722 0.434197875438884 0.622623368553871 PLEC/GPX1 2 GO:0032885 regulation of polysaccharide biosynthetic process 2/742 37/18722 0.434197875438884 0.622623368553871 CLTC/IGF2 2 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 2/742 37/18722 0.434197875438884 0.622623368553871 GPC1/GATA3 2 GO:0042178 xenobiotic catabolic process 2/742 37/18722 0.434197875438884 0.622623368553871 GSTO1/CYP2J2 2 GO:0043029 T cell homeostasis 2/742 37/18722 0.434197875438884 0.622623368553871 RPS6/PMAIP1 2 GO:0043687 post-translational protein modification 2/742 37/18722 0.434197875438884 0.622623368553871 P3H1/LCMT1 2 GO:0045730 respiratory burst 2/742 37/18722 0.434197875438884 0.622623368553871 GRN/CD55 2 GO:0060428 lung epithelium development 2/742 37/18722 0.434197875438884 0.622623368553871 SRSF6/CDC42 2 GO:1900016 negative regulation of cytokine production involved in inflammatory response 2/742 37/18722 0.434197875438884 0.622623368553871 CHID1/PDCD4 2 GO:1902745 positive regulation of lamellipodium organization 2/742 37/18722 0.434197875438884 0.622623368553871 WASF2/CDC42 2 GO:0002456 T cell mediated immunity 5/742 109/18722 0.434811555614777 0.623322427375797 CD46/CTSC/CD81/CD55/GATA3 5 GO:0044774 mitotic DNA integrity checkpoint signaling 4/742 85/18722 0.436594346995617 0.625515102714138 SOX4/RPL26/PRKDC/PPP1R10 4 GO:2000779 regulation of double-strand break repair 4/742 85/18722 0.436594346995617 0.625515102714138 FUS/PRKDC/RIF1/PARP1 4 GO:0006900 vesicle budding from membrane 3/742 61/18722 0.437232276238445 0.625703199483754 TMED9/MIA3/S100A10 3 GO:0030199 collagen fibril organization 3/742 61/18722 0.437232276238445 0.625703199483754 COL14A1/SERPINH1/NF1 3 GO:0060998 regulation of dendritic spine development 3/742 61/18722 0.437232276238445 0.625703199483754 DLG5/PPP1R9A/DHX36 3 GO:1905515 non-motile cilium assembly 3/742 61/18722 0.437232276238445 0.625703199483754 CEP350/TMEM107/PCM1 3 GO:0008277 regulation of G protein-coupled receptor signaling pathway 6/742 134/18722 0.439650625979704 0.628981781737544 MET/ATP2B4/ROCK1/NMT1/ADM/DYNLT1 6 GO:1905954 positive regulation of lipid localization 5/742 110/18722 0.442625192052554 0.633053980526814 LRP1/CAV1/PLIN2/NFKBIA/CYP19A1 5 GO:0009798 axis specification 4/742 86/18722 0.445461036078345 0.633577484506335 WLS/PGAP1/DDIT3/CITED2 4 GO:0045921 positive regulation of exocytosis 4/742 86/18722 0.445461036078345 0.633577484506335 ATP6AP1/SYT7/LAMP1/SDCBP 4 GO:0001101 response to acid chemical 6/742 135/18722 0.446696413420961 0.633577484506335 PLEC/UFL1/KRT8/ATP2B4/SLC38A9/RHOA 6 GO:0007588 excretion 3/742 62/18722 0.447732493549243 0.633577484506335 NFAT5/ATP6V1B1/CLN3 3 GO:0010573 vascular endothelial growth factor production 3/742 62/18722 0.447732493549243 0.633577484506335 ADGRG1/IL6ST/ISL1 3 GO:0031124 mRNA 3'-end processing 3/742 62/18722 0.447732493549243 0.633577484506335 APP/ZFP36L1/DHX36 3 GO:0032623 interleukin-2 production 3/742 62/18722 0.447732493549243 0.633577484506335 SPTBN1/ANXA1/GATA3 3 GO:0032663 regulation of interleukin-2 production 3/742 62/18722 0.447732493549243 0.633577484506335 SPTBN1/ANXA1/GATA3 3 GO:0032757 positive regulation of interleukin-8 production 3/742 62/18722 0.447732493549243 0.633577484506335 HSPA1A/HSPA1B/DDIT3 3 GO:0045428 regulation of nitric oxide biosynthetic process 3/742 62/18722 0.447732493549243 0.633577484506335 CAV1/DYNLL1/ATP2B4 3 GO:0048663 neuron fate commitment 3/742 62/18722 0.447732493549243 0.633577484506335 ISL1/GLI3/CDC42 3 GO:0070265 necrotic cell death 3/742 62/18722 0.447732493549243 0.633577484506335 CAV1/ASAH1/PYGL 3 GO:0008210 estrogen metabolic process 2/742 38/18722 0.447767211189726 0.633577484506335 HSD17B1/CYP19A1 2 GO:0010742 macrophage derived foam cell differentiation 2/742 38/18722 0.447767211189726 0.633577484506335 ITGAV/NFKBIA 2 GO:0032941 secretion by tissue 2/742 38/18722 0.447767211189726 0.633577484506335 EGFR/KCNN4 2 GO:0035136 forelimb morphogenesis 2/742 38/18722 0.447767211189726 0.633577484506335 ATRX/NIPBL 2 GO:0042491 inner ear auditory receptor cell differentiation 2/742 38/18722 0.447767211189726 0.633577484506335 TRIOBP/HES1 2 GO:0046633 alpha-beta T cell proliferation 2/742 38/18722 0.447767211189726 0.633577484506335 CD81/CD55 2 GO:0071392 cellular response to estradiol stimulus 2/742 38/18722 0.447767211189726 0.633577484506335 EGFR/NCOA3 2 GO:0090077 foam cell differentiation 2/742 38/18722 0.447767211189726 0.633577484506335 ITGAV/NFKBIA 2 GO:0060402 calcium ion transport into cytosol 7/742 160/18722 0.449628372549069 0.633577484506335 CAV1/GSTO1/ATP2B4/DIAPH1/DDIT3/CALM1/CALM2 7 GO:0001938 positive regulation of endothelial cell proliferation 5/742 111/18722 0.450412601801275 0.633577484506335 NRP2/NRP1/MYDGF/EMC10/IGF2 5 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 5/742 111/18722 0.450412601801275 0.633577484506335 EGFR/FLT1/IGF1R/MYDGF/ERBB3 5 GO:0001776 leukocyte homeostasis 4/742 87/18722 0.454284388795995 0.633577484506335 RPS6/JAM3/ANXA1/PMAIP1 4 GO:0002699 positive regulation of immune effector process 10/742 235/18722 0.454894746695583 0.633577484506335 CD46/CADM1/TFRC/CD81/ANXA1/CD55/LAMP1/DHX36/RIF1/GATA3 10 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/742 15/18722 0.45491889423967 0.633577484506335 RPL7 1 GO:0000478 endonucleolytic cleavage involved in rRNA processing 1/742 15/18722 0.45491889423967 0.633577484506335 RPS21 1 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/742 15/18722 0.45491889423967 0.633577484506335 RPS21 1 GO:0000722 telomere maintenance via recombination 1/742 15/18722 0.45491889423967 0.633577484506335 RAD50 1 GO:0002679 respiratory burst involved in defense response 1/742 15/18722 0.45491889423967 0.633577484506335 GRN 1 GO:0002730 regulation of dendritic cell cytokine production 1/742 15/18722 0.45491889423967 0.633577484506335 DHX36 1 GO:0006089 lactate metabolic process 1/742 15/18722 0.45491889423967 0.633577484506335 LDHA 1 GO:0006878 cellular copper ion homeostasis 1/742 15/18722 0.45491889423967 0.633577484506335 APP 1 GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process 1/742 15/18722 0.45491889423967 0.633577484506335 NME3 1 GO:0010713 negative regulation of collagen metabolic process 1/742 15/18722 0.45491889423967 0.633577484506335 CST3 1 GO:0010763 positive regulation of fibroblast migration 1/742 15/18722 0.45491889423967 0.633577484506335 ITGB1 1 GO:0010889 regulation of sequestering of triglyceride 1/742 15/18722 0.45491889423967 0.633577484506335 PLIN2 1 GO:0015671 oxygen transport 1/742 15/18722 0.45491889423967 0.633577484506335 HBA2 1 GO:0015697 quaternary ammonium group transport 1/742 15/18722 0.45491889423967 0.633577484506335 SLC38A2 1 GO:0018146 keratan sulfate biosynthetic process 1/742 15/18722 0.45491889423967 0.633577484506335 B4GAT1 1 GO:0018410 C-terminal protein amino acid modification 1/742 15/18722 0.45491889423967 0.633577484506335 LCMT1 1 GO:0021542 dentate gyrus development 1/742 15/18722 0.45491889423967 0.633577484506335 CDK6 1 GO:0023035 CD40 signaling pathway 1/742 15/18722 0.45491889423967 0.633577484506335 ITGB1 1 GO:0031269 pseudopodium assembly 1/742 15/18722 0.45491889423967 0.633577484506335 CDC42 1 GO:0032239 regulation of nucleobase-containing compound transport 1/742 15/18722 0.45491889423967 0.633577484506335 TPR 1 GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 1/742 15/18722 0.45491889423967 0.633577484506335 ISL1 1 GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway 1/742 15/18722 0.45491889423967 0.633577484506335 CITED2 1 GO:0035493 SNARE complex assembly 1/742 15/18722 0.45491889423967 0.633577484506335 VAMP2 1 GO:0035627 ceramide transport 1/742 15/18722 0.45491889423967 0.633577484506335 PSAP 1 GO:0036124 histone H3-K9 trimethylation 1/742 15/18722 0.45491889423967 0.633577484506335 ATRX 1 GO:0042074 cell migration involved in gastrulation 1/742 15/18722 0.45491889423967 0.633577484506335 LRP5 1 GO:0042976 activation of Janus kinase activity 1/742 15/18722 0.45491889423967 0.633577484506335 PRLR 1 GO:0043508 negative regulation of JUN kinase activity 1/742 15/18722 0.45491889423967 0.633577484506335 PDCD4 1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 1/742 15/18722 0.45491889423967 0.633577484506335 MIF 1 GO:0043584 nose development 1/742 15/18722 0.45491889423967 0.633577484506335 GLI3 1 GO:0043981 histone H4-K5 acetylation 1/742 15/18722 0.45491889423967 0.633577484506335 PHF20 1 GO:0043982 histone H4-K8 acetylation 1/742 15/18722 0.45491889423967 0.633577484506335 PHF20 1 GO:0044406 adhesion of symbiont to host 1/742 15/18722 0.45491889423967 0.633577484506335 CD81 1 GO:0044793 negative regulation by host of viral process 1/742 15/18722 0.45491889423967 0.633577484506335 EIF2AK4 1 GO:0045725 positive regulation of glycogen biosynthetic process 1/742 15/18722 0.45491889423967 0.633577484506335 IGF2 1 GO:0045842 positive regulation of mitotic metaphase/anaphase transition 1/742 15/18722 0.45491889423967 0.633577484506335 ANAPC11 1 GO:0046184 aldehyde biosynthetic process 1/742 15/18722 0.45491889423967 0.633577484506335 TPI1 1 GO:0046459 short-chain fatty acid metabolic process 1/742 15/18722 0.45491889423967 0.633577484506335 ACSS1 1 GO:0050746 regulation of lipoprotein metabolic process 1/742 15/18722 0.45491889423967 0.633577484506335 ITGAV 1 GO:0051127 positive regulation of actin nucleation 1/742 15/18722 0.45491889423967 0.633577484506335 WASF2 1 GO:0051299 centrosome separation 1/742 15/18722 0.45491889423967 0.633577484506335 RANBP1 1 GO:0051791 medium-chain fatty acid metabolic process 1/742 15/18722 0.45491889423967 0.633577484506335 CROT 1 GO:0060049 regulation of protein glycosylation 1/742 15/18722 0.45491889423967 0.633577484506335 TMEM59 1 GO:0060253 negative regulation of glial cell proliferation 1/742 15/18722 0.45491889423967 0.633577484506335 HES1 1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport 1/742 15/18722 0.45491889423967 0.633577484506335 PGAP1 1 GO:0070071 proton-transporting two-sector ATPase complex assembly 1/742 15/18722 0.45491889423967 0.633577484506335 ATP6V1B1 1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade 1/742 15/18722 0.45491889423967 0.633577484506335 ATP2B4 1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade 1/742 15/18722 0.45491889423967 0.633577484506335 SLC9A1 1 GO:0071599 otic vesicle development 1/742 15/18722 0.45491889423967 0.633577484506335 GATA3 1 GO:0072044 collecting duct development 1/742 15/18722 0.45491889423967 0.633577484506335 DLG5 1 GO:0072075 metanephric mesenchyme development 1/742 15/18722 0.45491889423967 0.633577484506335 BMP7 1 GO:0090110 COPII-coated vesicle cargo loading 1/742 15/18722 0.45491889423967 0.633577484506335 MIA3 1 GO:0090594 inflammatory response to wounding 1/742 15/18722 0.45491889423967 0.633577484506335 GRN 1 GO:0097468 programmed cell death in response to reactive oxygen species 1/742 15/18722 0.45491889423967 0.633577484506335 MET 1 GO:0099170 postsynaptic modulation of chemical synaptic transmission 1/742 15/18722 0.45491889423967 0.633577484506335 CDH1 1 GO:0106057 negative regulation of calcineurin-mediated signaling 1/742 15/18722 0.45491889423967 0.633577484506335 ATP2B4 1 GO:0106058 positive regulation of calcineurin-mediated signaling 1/742 15/18722 0.45491889423967 0.633577484506335 SLC9A1 1 GO:0150011 regulation of neuron projection arborization 1/742 15/18722 0.45491889423967 0.633577484506335 MACF1 1 GO:1901841 regulation of high voltage-gated calcium channel activity 1/742 15/18722 0.45491889423967 0.633577484506335 CALM1 1 GO:1901970 positive regulation of mitotic sister chromatid separation 1/742 15/18722 0.45491889423967 0.633577484506335 ANAPC11 1 GO:1903543 positive regulation of exosomal secretion 1/742 15/18722 0.45491889423967 0.633577484506335 SDCBP 1 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA 1/742 15/18722 0.45491889423967 0.633577484506335 NCOR1 1 GO:1904874 positive regulation of telomerase RNA localization to Cajal body 1/742 15/18722 0.45491889423967 0.633577484506335 CCT3 1 GO:1905288 vascular associated smooth muscle cell apoptotic process 1/742 15/18722 0.45491889423967 0.633577484506335 PDCD4 1 GO:1905459 regulation of vascular associated smooth muscle cell apoptotic process 1/742 15/18722 0.45491889423967 0.633577484506335 PDCD4 1 GO:1990822 basic amino acid transmembrane transport 1/742 15/18722 0.45491889423967 0.633577484506335 SLC38A9 1 GO:2000402 negative regulation of lymphocyte migration 1/742 15/18722 0.45491889423967 0.633577484506335 MIA3 1 GO:2001279 regulation of unsaturated fatty acid biosynthetic process 1/742 15/18722 0.45491889423967 0.633577484506335 ANXA1 1 GO:0006260 DNA replication 11/742 260/18722 0.45598495594516 0.634840542806286 JUN/EGFR/BOD1L1/ATRX/RBBP6/PURA/CDC42/HMGA1/PTMS/CCNE1/CACYBP 11 GO:0051650 establishment of vesicle localization 7/742 161/18722 0.456082811016095 0.634840542806286 DYNC1H1/TMED9/TRIP11/KIF5B/ACTN4/CLN3/RAB11A 7 GO:0002704 negative regulation of leukocyte mediated immunity 3/742 63/18722 0.458153011997316 0.63720884493408 CD46/CD55/SERPINB9 3 GO:0001676 long-chain fatty acid metabolic process 5/742 112/18722 0.458171218057865 0.63720884493408 SLC27A2/GPX1/PTGES3/CYP2J2/GPX4 5 GO:0035601 protein deacylation 5/742 112/18722 0.458171218057865 0.63720884493408 KDM5A/NIPBL/TBL1X/NOTUM/MORF4L2 5 GO:0016072 rRNA metabolic process 10/742 236/18722 0.460224276102482 0.639552942827712 RPS21/RPS6/RPS16/RPL14/RPL7/RPS25/RPL26/PRKDC/DDX17/RPS17 10 GO:0034754 cellular hormone metabolic process 6/742 137/18722 0.46072983660922 0.639552942827712 EGR1/ADM/DHRS2/CYP11A1/HSD17B1/CYP19A1 6 GO:0010463 mesenchymal cell proliferation 2/742 39/18722 0.461151332459982 0.639552942827712 LRP5/BMP7 2 GO:0016233 telomere capping 2/742 39/18722 0.461151332459982 0.639552942827712 PRKDC/RAD50 2 GO:0031507 heterochromatin assembly 2/742 39/18722 0.461151332459982 0.639552942827712 MPHOSPH8/TPR 2 GO:0032506 cytokinetic process 2/742 39/18722 0.461151332459982 0.639552942827712 PLEC/RHOA 2 GO:0043267 negative regulation of potassium ion transport 2/742 39/18722 0.461151332459982 0.639552942827712 CAV1/ANK3 2 GO:0051154 negative regulation of striated muscle cell differentiation 2/742 39/18722 0.461151332459982 0.639552942827712 YBX1/YY1 2 GO:0071548 response to dexamethasone 2/742 39/18722 0.461151332459982 0.639552942827712 EGFR/SERPINF1 2 GO:1902742 apoptotic process involved in development 2/742 39/18722 0.461151332459982 0.639552942827712 LRP5/BMP7 2 GO:0001885 endothelial cell development 3/742 64/18722 0.468488944911627 0.647621297325717 MET/ROCK1/GPX1 3 GO:0006940 regulation of smooth muscle contraction 3/742 64/18722 0.468488944911627 0.647621297325717 ATP2B1/CAV1/RHOA 3 GO:0016126 sterol biosynthetic process 3/742 64/18722 0.468488944911627 0.647621297325717 DHCR24/POR/MBTPS1 3 GO:0017156 calcium-ion regulated exocytosis 3/742 64/18722 0.468488944911627 0.647621297325717 SYT7/VAMP2/SDF4 3 GO:0046579 positive regulation of Ras protein signal transduction 3/742 64/18722 0.468488944911627 0.647621297325717 ADGRG1/AKAP13/DYNLT1 3 GO:0080164 regulation of nitric oxide metabolic process 3/742 64/18722 0.468488944911627 0.647621297325717 CAV1/DYNLL1/ATP2B4 3 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process 3/742 64/18722 0.468488944911627 0.647621297325717 RPL23/EIF3H/SDCBP 3 GO:0001906 cell killing 8/742 188/18722 0.469804612349105 0.647621297325717 GAPDH/CTSC/CADM1/KIF5B/CD55/LAMP1/SERPINB9/TUBB4B 8 GO:0019751 polyol metabolic process 5/742 114/18722 0.473592187857573 0.647621297325717 PLPP3/TPI1/SLC5A3/ISYNA1/ASAH1 5 GO:0002714 positive regulation of B cell mediated immunity 2/742 40/18722 0.474343595944849 0.647621297325717 TFRC/RIF1 2 GO:0002891 positive regulation of immunoglobulin mediated immune response 2/742 40/18722 0.474343595944849 0.647621297325717 TFRC/RIF1 2 GO:0009069 serine family amino acid metabolic process 2/742 40/18722 0.474343595944849 0.647621297325717 GLDC/SERINC3 2 GO:0031297 replication fork processing 2/742 40/18722 0.474343595944849 0.647621297325717 BOD1L1/ATRX 2 GO:0032094 response to food 2/742 40/18722 0.474343595944849 0.647621297325717 PLEC/SLC16A1 2 GO:0042073 intraciliary transport 2/742 40/18722 0.474343595944849 0.647621297325717 IFT27/PCM1 2 GO:0045022 early endosome to late endosome transport 2/742 40/18722 0.474343595944849 0.647621297325717 EEA1/HOOK2 2 GO:0055081 anion homeostasis 2/742 40/18722 0.474343595944849 0.647621297325717 SLC12A9/ATP6V1B1 2 GO:0070266 necroptotic process 2/742 40/18722 0.474343595944849 0.647621297325717 CAV1/PYGL 2 GO:0150077 regulation of neuroinflammatory response 2/742 40/18722 0.474343595944849 0.647621297325717 GRN/CTSC 2 GO:1901223 negative regulation of NIK/NF-kappaB signaling 2/742 40/18722 0.474343595944849 0.647621297325717 BMP7/TMSB4X 2 GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell 2/742 40/18722 0.474343595944849 0.647621297325717 NFAT5/RHOA 2 GO:2000142 regulation of DNA-templated transcription, initiation 2/742 40/18722 0.474343595944849 0.647621297325717 JUN/DHX36 2 GO:0016579 protein deubiquitination 6/742 139/18722 0.474672977967078 0.647621297325717 USP9X/USP27X/USP22/USP48/USP10/EIF3F 6 GO:0002700 regulation of production of molecular mediator of immune response 7/742 164/18722 0.475346304892972 0.647621297325717 TFRC/PRKDC/CD81/CD55/DHX36/RIF1/GATA3 7 GO:0072330 monocarboxylic acid biosynthetic process 9/742 214/18722 0.476021881879402 0.647621297325717 ACSS1/MIF/SLC27A2/HACD3/DEGS1/ANXA1/ACADVL/PTGES3/GPX4 9 GO:0006790 sulfur compound metabolic process 14/742 339/18722 0.476069793893879 0.647621297325717 SLC26A2/CHPF/ACSS1/TPST2/GSTO1/ARL6IP5/CLIC3/B4GAT1/GNS/SLC19A3/GLB1/MTR/GPX1/GPX4 14 GO:0002093 auditory receptor cell morphogenesis 1/742 16/18722 0.476539152991697 0.647621297325717 TRIOBP 1 GO:0002371 dendritic cell cytokine production 1/742 16/18722 0.476539152991697 0.647621297325717 DHX36 1 GO:0002566 somatic diversification of immune receptors via somatic mutation 1/742 16/18722 0.476539152991697 0.647621297325717 ADAR 1 GO:0002693 positive regulation of cellular extravasation 1/742 16/18722 0.476539152991697 0.647621297325717 JAM3 1 GO:0006349 regulation of gene expression by genetic imprinting 1/742 16/18722 0.476539152991697 0.647621297325717 IGF2 1 GO:0006544 glycine metabolic process 1/742 16/18722 0.476539152991697 0.647621297325717 GLDC 1 GO:0006555 methionine metabolic process 1/742 16/18722 0.476539152991697 0.647621297325717 MTR 1 GO:0006828 manganese ion transport 1/742 16/18722 0.476539152991697 0.647621297325717 TMEM165 1 GO:0006857 oligopeptide transport 1/742 16/18722 0.476539152991697 0.647621297325717 GJA1 1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 1/742 16/18722 0.476539152991697 0.647621297325717 RPL26 1 GO:0009299 mRNA transcription 1/742 16/18722 0.476539152991697 0.647621297325717 DDX5 1 GO:0010225 response to UV-C 1/742 16/18722 0.476539152991697 0.647621297325717 YY1 1 GO:0014819 regulation of skeletal muscle contraction 1/742 16/18722 0.476539152991697 0.647621297325717 GSTO1 1 GO:0016584 nucleosome positioning 1/742 16/18722 0.476539152991697 0.647621297325717 RSF1 1 GO:0030540 female genitalia development 1/742 16/18722 0.476539152991697 0.647621297325717 LRP2 1 GO:0030575 nuclear body organization 1/742 16/18722 0.476539152991697 0.647621297325717 SF1 1 GO:0031268 pseudopodium organization 1/742 16/18722 0.476539152991697 0.647621297325717 CDC42 1 GO:0034116 positive regulation of heterotypic cell-cell adhesion 1/742 16/18722 0.476539152991697 0.647621297325717 BMP7 1 GO:0034393 positive regulation of smooth muscle cell apoptotic process 1/742 16/18722 0.476539152991697 0.647621297325717 PDCD4 1 GO:0035970 peptidyl-threonine dephosphorylation 1/742 16/18722 0.476539152991697 0.647621297325717 DUSP1 1 GO:0043923 positive regulation by host of viral transcription 1/742 16/18722 0.476539152991697 0.647621297325717 JUN 1 GO:0044804 autophagy of nucleus 1/742 16/18722 0.476539152991697 0.647621297325717 RB1CC1 1 GO:0044849 estrous cycle 1/742 16/18722 0.476539152991697 0.647621297325717 EGR1 1 GO:0045722 positive regulation of gluconeogenesis 1/742 16/18722 0.476539152991697 0.647621297325717 DDB1 1 GO:0045838 positive regulation of membrane potential 1/742 16/18722 0.476539152991697 0.647621297325717 ANK3 1 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate 1/742 16/18722 0.476539152991697 0.647621297325717 MPHOSPH8 1 GO:0046036 CTP metabolic process 1/742 16/18722 0.476539152991697 0.647621297325717 NME3 1 GO:0046037 GMP metabolic process 1/742 16/18722 0.476539152991697 0.647621297325717 DLG1 1 GO:0048385 regulation of retinoic acid receptor signaling pathway 1/742 16/18722 0.476539152991697 0.647621297325717 CALR 1 GO:0050965 detection of temperature stimulus involved in sensory perception of pain 1/742 16/18722 0.476539152991697 0.647621297325717 NR2F6 1 GO:0060572 morphogenesis of an epithelial bud 1/742 16/18722 0.476539152991697 0.647621297325717 BMP7 1 GO:0070200 establishment of protein localization to telomere 1/742 16/18722 0.476539152991697 0.647621297325717 CCT3 1 GO:0070242 thymocyte apoptotic process 1/742 16/18722 0.476539152991697 0.647621297325717 GLI3 1 GO:0071391 cellular response to estrogen stimulus 1/742 16/18722 0.476539152991697 0.647621297325717 SERPINB9 1 GO:0071732 cellular response to nitric oxide 1/742 16/18722 0.476539152991697 0.647621297325717 MTR 1 GO:0080009 mRNA methylation 1/742 16/18722 0.476539152991697 0.647621297325717 ZC3H13 1 GO:0090336 positive regulation of brown fat cell differentiation 1/742 16/18722 0.476539152991697 0.647621297325717 BMP7 1 GO:0099116 tRNA 5'-end processing 1/742 16/18722 0.476539152991697 0.647621297325717 SSB 1 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration 1/742 16/18722 0.476539152991697 0.647621297325717 ATP2B1 1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway 1/742 16/18722 0.476539152991697 0.647621297325717 SEMA6A 1 GO:1901201 regulation of extracellular matrix assembly 1/742 16/18722 0.476539152991697 0.647621297325717 DAG1 1 GO:1902101 positive regulation of metaphase/anaphase transition of cell cycle 1/742 16/18722 0.476539152991697 0.647621297325717 ANAPC11 1 GO:1904683 regulation of metalloendopeptidase activity 1/742 16/18722 0.476539152991697 0.647621297325717 TIMP3 1 GO:1905906 regulation of amyloid fibril formation 1/742 16/18722 0.476539152991697 0.647621297325717 APP 1 GO:2000001 regulation of DNA damage checkpoint 1/742 16/18722 0.476539152991697 0.647621297325717 PPP1R10 1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway 1/742 16/18722 0.476539152991697 0.647621297325717 ZNRF3 1 GO:2001212 regulation of vasculogenesis 1/742 16/18722 0.476539152991697 0.647621297325717 ADM 1 GO:0046513 ceramide biosynthetic process 3/742 65/18722 0.478735706865384 0.650248664260379 ORMDL1/DEGS1/ASAH1 3 GO:0051310 metaphase plate congression 3/742 65/18722 0.478735706865384 0.650248664260379 DYNC1H1/KPNB1/RAB11A 3 GO:0045638 negative regulation of myeloid cell differentiation 4/742 90/18722 0.480460594483498 0.652232848790459 FBN1/ZFP36L1/CDK6/NFKBIA 4 GO:0099175 regulation of postsynapse organization 4/742 90/18722 0.480460594483498 0.652232848790459 NRP2/PPP1R9A/CFL1/DHX36 4 GO:0000077 DNA damage checkpoint signaling 5/742 115/18722 0.481249793739603 0.652766057406271 SOX4/RPL26/PRKDC/PPP1R10/EIF2AK4 5 GO:0042471 ear morphogenesis 5/742 115/18722 0.481249793739603 0.652766057406271 NAGLU/NIPBL/TRIOBP/ATP6V1B1/GATA3 5 GO:0051209 release of sequestered calcium ion into cytosol 5/742 115/18722 0.481249793739603 0.652766057406271 GSTO1/DIAPH1/DDIT3/CALM1/CALM2 5 GO:0007292 female gamete generation 6/742 140/18722 0.481606090818921 0.653037588540036 RPS6/LGR5/ADAMTS1/USP9X/HEXB/HPGD 6 GO:0046390 ribose phosphate biosynthetic process 8/742 190/18722 0.481714366931152 0.653037588540036 SLC26A2/ALDOA/ACSS1/TMSB4X/ENO1/NME3/PARP1/PYGL 8 GO:0071824 protein-DNA complex subunit organization 10/742 241/18722 0.486732836417443 0.659394845268486 BPTF/ATRX/RPL23/NPM1/BDP1/ARID1A/BRD2/HP1BP3/RSF1/HMGA1 10 GO:0001953 negative regulation of cell-matrix adhesion 2/742 41/18722 0.4873381741043 0.659394845268486 LRP1/RASA1 2 GO:0050691 regulation of defense response to virus by host 2/742 41/18722 0.4873381741043 0.659394845268486 TRIM44/EIF2AK4 2 GO:0060612 adipose tissue development 2/742 41/18722 0.4873381741043 0.659394845268486 LRP5/ARID5B 2 GO:1901385 regulation of voltage-gated calcium channel activity 2/742 41/18722 0.4873381741043 0.659394845268486 AHNAK/CALM1 2 GO:1902622 regulation of neutrophil migration 2/742 41/18722 0.4873381741043 0.659394845268486 DPP4/JAM3 2 GO:1905521 regulation of macrophage migration 2/742 41/18722 0.4873381741043 0.659394845268486 MIF/CD81 2 GO:0006119 oxidative phosphorylation 6/742 141/18722 0.488511206671203 0.65958031567675 COX6A1/NDUFB9/UQCRH/COX8C/RHOA/COX5A 6 GO:0034341 response to interferon-gamma 6/742 141/18722 0.488511206671203 0.65958031567675 GAPDH/RPL13A/KIF5B/ACTG1/SEC61A1/CDC42 6 GO:0008286 insulin receptor signaling pathway 5/742 116/18722 0.488869111165848 0.65958031567675 KANK1/IGF1R/PHIP/PTPRA/IGF2 5 GO:0031123 RNA 3'-end processing 5/742 116/18722 0.488869111165848 0.65958031567675 RPS21/APP/ZFP36L1/DHX36/SSB 5 GO:0051283 negative regulation of sequestering of calcium ion 5/742 116/18722 0.488869111165848 0.65958031567675 GSTO1/DIAPH1/DDIT3/CALM1/CALM2 5 GO:0098732 macromolecule deacylation 5/742 116/18722 0.488869111165848 0.65958031567675 KDM5A/NIPBL/TBL1X/NOTUM/MORF4L2 5 GO:0042093 T-helper cell differentiation 3/742 66/18722 0.488889005848176 0.65958031567675 ANXA1/FOXP1/GATA3 3 GO:0050766 positive regulation of phagocytosis 3/742 66/18722 0.488889005848176 0.65958031567675 LRP1/CALR/LMAN2 3 GO:2000573 positive regulation of DNA biosynthetic process 3/742 66/18722 0.488889005848176 0.65958031567675 HNRNPA1/PTGES3/CCT3 3 GO:0002065 columnar/cuboidal epithelial cell differentiation 4/742 91/18722 0.489077468891485 0.65958031567675 SOX4/IL6ST/CDK6/HES1 4 GO:0006354 DNA-templated transcription, elongation 4/742 91/18722 0.489077468891485 0.65958031567675 BRD4/SERTAD1/ARID1A/RTF1 4 GO:0051952 regulation of amine transport 4/742 91/18722 0.489077468891485 0.65958031567675 ITGB1/SLC43A2/ARL6IP5/SYT7 4 GO:0097553 calcium ion transmembrane import into cytosol 6/742 142/18722 0.49538661732398 0.660929961932998 GSTO1/ATP2B4/DIAPH1/DDIT3/CALM1/CALM2 6 GO:0043543 protein acylation 10/742 243/18722 0.497255294979905 0.660929961932998 SOX4/ISL1/POR/NMT1/NCOA3/BRD7/GATA3/USP22/PHF20/MORF4L2 10 GO:0000097 sulfur amino acid biosynthetic process 1/742 17/18722 0.497302969332986 0.660929961932998 MTR 1 GO:0002031 G protein-coupled receptor internalization 1/742 17/18722 0.497302969332986 0.660929961932998 ADM 1 GO:0003184 pulmonary valve morphogenesis 1/742 17/18722 0.497302969332986 0.660929961932998 GJA5 1 GO:0006474 N-terminal protein amino acid acetylation 1/742 17/18722 0.497302969332986 0.660929961932998 SOX4 1 GO:0006895 Golgi to endosome transport 1/742 17/18722 0.497302969332986 0.660929961932998 VPS13C 1 GO:0006901 vesicle coating 1/742 17/18722 0.497302969332986 0.660929961932998 TMED9 1 GO:0007096 regulation of exit from mitosis 1/742 17/18722 0.497302969332986 0.660929961932998 UBE2C 1 GO:0007379 segment specification 1/742 17/18722 0.497302969332986 0.660929961932998 IRX2 1 GO:0008334 histone mRNA metabolic process 1/742 17/18722 0.497302969332986 0.660929961932998 SSB 1 GO:0009084 glutamine family amino acid biosynthetic process 1/742 17/18722 0.497302969332986 0.660929961932998 CLN3 1 GO:0009812 flavonoid metabolic process 1/742 17/18722 0.497302969332986 0.660929961932998 POR 1 GO:0010224 response to UV-B 1/742 17/18722 0.497302969332986 0.660929961932998 MME 1 GO:0010470 regulation of gastrulation 1/742 17/18722 0.497302969332986 0.660929961932998 DAG1 1 GO:0010612 regulation of cardiac muscle adaptation 1/742 17/18722 0.497302969332986 0.660929961932998 ATP2B4 1 GO:0015867 ATP transport 1/742 17/18722 0.497302969332986 0.660929961932998 GJA1 1 GO:0021513 spinal cord dorsal/ventral patterning 1/742 17/18722 0.497302969332986 0.660929961932998 GLI3 1 GO:0030322 stabilization of membrane potential 1/742 17/18722 0.497302969332986 0.660929961932998 KCNN4 1 GO:0032048 cardiolipin metabolic process 1/742 17/18722 0.497302969332986 0.660929961932998 HADHA 1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway 1/742 17/18722 0.497302969332986 0.660929961932998 LEPROT 1 GO:0032604 granulocyte macrophage colony-stimulating factor production 1/742 17/18722 0.497302969332986 0.660929961932998 ISL1 1 GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 1/742 17/18722 0.497302969332986 0.660929961932998 ISL1 1 GO:0035269 protein O-linked mannosylation 1/742 17/18722 0.497302969332986 0.660929961932998 B4GAT1 1 GO:0035855 megakaryocyte development 1/742 17/18722 0.497302969332986 0.660929961932998 WASF2 1 GO:0036065 fucosylation 1/742 17/18722 0.497302969332986 0.660929961932998 FUT8 1 GO:0038065 collagen-activated signaling pathway 1/742 17/18722 0.497302969332986 0.660929961932998 COL4A2 1 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 1/742 17/18722 0.497302969332986 0.660929961932998 CAV1 1 GO:0042772 DNA damage response, signal transduction resulting in transcription 1/742 17/18722 0.497302969332986 0.660929961932998 RPL26 1 GO:0043968 histone H2A acetylation 1/742 17/18722 0.497302969332986 0.660929961932998 MORF4L2 1 GO:0045591 positive regulation of regulatory T cell differentiation 1/742 17/18722 0.497302969332986 0.660929961932998 CD46 1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter 1/742 17/18722 0.497302969332986 0.660929961932998 SYT7 1 GO:0051580 regulation of neurotransmitter uptake 1/742 17/18722 0.497302969332986 0.660929961932998 ITGB1 1 GO:0051797 regulation of hair follicle development 1/742 17/18722 0.497302969332986 0.660929961932998 FERMT1 1 GO:0055003 cardiac myofibril assembly 1/742 17/18722 0.497302969332986 0.660929961932998 OBSL1 1 GO:0055119 relaxation of cardiac muscle 1/742 17/18722 0.497302969332986 0.660929961932998 ATP1A1 1 GO:0060263 regulation of respiratory burst 1/742 17/18722 0.497302969332986 0.660929961932998 GRN 1 GO:0060644 mammary gland epithelial cell differentiation 1/742 17/18722 0.497302969332986 0.660929961932998 LBH 1 GO:0070593 dendrite self-avoidance 1/742 17/18722 0.497302969332986 0.660929961932998 BSG 1 GO:0070875 positive regulation of glycogen metabolic process 1/742 17/18722 0.497302969332986 0.660929961932998 IGF2 1 GO:0071371 cellular response to gonadotropin stimulus 1/742 17/18722 0.497302969332986 0.660929961932998 POR 1 GO:0090399 replicative senescence 1/742 17/18722 0.497302969332986 0.660929961932998 MME 1 GO:0097067 cellular response to thyroid hormone stimulus 1/742 17/18722 0.497302969332986 0.660929961932998 CTSL 1 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity 1/742 17/18722 0.497302969332986 0.660929961932998 AKAP9 1 GO:1900034 regulation of cellular response to heat 1/742 17/18722 0.497302969332986 0.660929961932998 DNAJB1 1 GO:1901550 regulation of endothelial cell development 1/742 17/18722 0.497302969332986 0.660929961932998 ROCK1 1 GO:1901569 fatty acid derivative catabolic process 1/742 17/18722 0.497302969332986 0.660929961932998 HPGD 1 GO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II 1/742 17/18722 0.497302969332986 0.660929961932998 YY1 1 GO:1903140 regulation of establishment of endothelial barrier 1/742 17/18722 0.497302969332986 0.660929961932998 ROCK1 1 GO:1903242 regulation of cardiac muscle hypertrophy in response to stress 1/742 17/18722 0.497302969332986 0.660929961932998 ATP2B4 1 GO:1903358 regulation of Golgi organization 1/742 17/18722 0.497302969332986 0.660929961932998 AKAP9 1 GO:1903541 regulation of exosomal secretion 1/742 17/18722 0.497302969332986 0.660929961932998 SDCBP 1 GO:1903830 magnesium ion transmembrane transport 1/742 17/18722 0.497302969332986 0.660929961932998 TUSC3 1 GO:2000696 regulation of epithelial cell differentiation involved in kidney development 1/742 17/18722 0.497302969332986 0.660929961932998 GATA3 1 GO:0006513 protein monoubiquitination 3/742 67/18722 0.498944835256048 0.662221248297926 DDB1/HUWE1/SKP1 3 GO:0009583 detection of light stimulus 3/742 67/18722 0.498944835256048 0.662221248297926 NMT1/CDS1/GNAQ 3 GO:0032890 regulation of organic acid transport 3/742 67/18722 0.498944835256048 0.662221248297926 ITGB1/SLC43A2/ARL6IP5 3 GO:0043967 histone H4 acetylation 3/742 67/18722 0.498944835256048 0.662221248297926 USP22/PHF20/MORF4L2 3 GO:1902117 positive regulation of organelle assembly 3/742 67/18722 0.498944835256048 0.662221248297926 DYNC1H1/RHOA/SDCBP 3 GO:0010939 regulation of necrotic cell death 2/742 42/18722 0.500130001090419 0.662903730986496 CAV1/ASAH1 2 GO:0021575 hindbrain morphogenesis 2/742 42/18722 0.500130001090419 0.662903730986496 HSPA5/HES1 2 GO:0032689 negative regulation of interferon-gamma production 2/742 42/18722 0.500130001090419 0.662903730986496 DDIT3/GATA3 2 GO:0046688 response to copper ion 2/742 42/18722 0.500130001090419 0.662903730986496 APP/SOD3 2 GO:0051602 response to electrical stimulus 2/742 42/18722 0.500130001090419 0.662903730986496 AKAP9/SLC9A1 2 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 7/742 168/18722 0.500743717832913 0.663361213755588 CD46/TFRC/CD81/ANXA1/CD55/RIF1/GATA3 7 GO:2000241 regulation of reproductive process 7/742 168/18722 0.500743717832913 0.663361213755588 SERPINF1/DUSP1/GJA1/BMP7/CALR/CITED2/PRDX4 7 GO:0016042 lipid catabolic process 13/742 320/18722 0.503776155766131 0.667117401181642 LRP1/HEXA/SLC27A2/FUCA1/CROT/ACADVL/ASAH1/HADHA/PLBD1/PRDX6/HEXB/CYP19A1/ETFA 13 GO:0051282 regulation of sequestering of calcium ion 5/742 118/18722 0.503984239111313 0.667117401181642 GSTO1/DIAPH1/DDIT3/CALM1/CALM2 5 GO:0071346 cellular response to interferon-gamma 5/742 118/18722 0.503984239111313 0.667117401181642 GAPDH/RPL13A/KIF5B/ACTG1/CDC42 5 GO:0050777 negative regulation of immune response 8/742 194/18722 0.505319983920431 0.668706327502526 CD46/GRN/ANXA1/CD55/PCBP2/ADAR/GPX1/SERPINB9 8 GO:0019221 cytokine-mediated signaling pathway 19/742 472/18722 0.505710326482079 0.668883454994508 CSF3R/P4HB/CAV1/IL6ST/EGR1/KRT8/PRLR/IL10RB/TMSB4X/HSPA1A/TRIM44/ACTN4/HSPA1B/SPPL2B/NFKBIA/KRT18/ADAR/CSNK2B/EIF5A 19 GO:0007589 body fluid secretion 4/742 93/18722 0.506130841046452 0.668883454994508 EGFR/KCNN4/CAV1/PRLR 4 GO:0019217 regulation of fatty acid metabolic process 4/742 93/18722 0.506130841046452 0.668883454994508 CAV1/ANXA1/NCOR1/ACADVL 4 GO:0033273 response to vitamin 4/742 93/18722 0.506130841046452 0.668883454994508 EGFR/ATP2B1/BMP7/FOLR1 4 GO:0097306 cellular response to alcohol 4/742 93/18722 0.506130841046452 0.668883454994508 ATP2B1/CDH1/DAG1/LARP1 4 GO:0009152 purine ribonucleotide biosynthetic process 7/742 169/18722 0.50703256138083 0.66989592223089 SLC26A2/ALDOA/ACSS1/TMSB4X/ENO1/NME3/PARP1 7 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 3/742 68/18722 0.5088994657391 0.671823452899827 ANXA1/FOXP1/GATA3 3 GO:0034394 protein localization to cell surface 3/742 68/18722 0.5088994657391 0.671823452899827 JAM3/LEPROT/RAB11A 3 GO:0046686 response to cadmium ion 3/742 68/18722 0.5088994657391 0.671823452899827 JUN/EGFR/FOS 3 GO:0002861 regulation of inflammatory response to antigenic stimulus 2/742 43/18722 0.512714721670015 0.67241749316049 CD81/GPX1 2 GO:0014014 negative regulation of gliogenesis 2/742 43/18722 0.512714721670015 0.67241749316049 NF1/HES1 2 GO:0045776 negative regulation of blood pressure 2/742 43/18722 0.512714721670015 0.67241749316049 GJA5/ADRB1 2 GO:0046636 negative regulation of alpha-beta T cell activation 2/742 43/18722 0.512714721670015 0.67241749316049 ANXA1/GLI3 2 GO:0098927 vesicle-mediated transport between endosomal compartments 2/742 43/18722 0.512714721670015 0.67241749316049 EEA1/HOOK2 2 GO:0140353 lipid export from cell 2/742 43/18722 0.512714721670015 0.67241749316049 KDM5B/CYP19A1 2 GO:1901381 positive regulation of potassium ion transmembrane transport 2/742 43/18722 0.512714721670015 0.67241749316049 AKAP9/KCNN4 2 GO:1903793 positive regulation of anion transport 2/742 43/18722 0.512714721670015 0.67241749316049 TCAF1/ITGB1 2 GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 2/742 43/18722 0.512714721670015 0.67241749316049 HSPA1A/HSPA1B 2 GO:0010389 regulation of G2/M transition of mitotic cell cycle 4/742 94/18722 0.514561952817857 0.67241749316049 APP/PBX1/BRD4/RAB11A 4 GO:0001946 lymphangiogenesis 1/742 18/18722 0.517244225508069 0.67241749316049 PTPN14 1 GO:0002283 neutrophil activation involved in immune response 1/742 18/18722 0.517244225508069 0.67241749316049 ANXA3 1 GO:0002501 peptide antigen assembly with MHC protein complex 1/742 18/18722 0.517244225508069 0.67241749316049 CALR 1 GO:0003417 growth plate cartilage development 1/742 18/18722 0.517244225508069 0.67241749316049 POR 1 GO:0006085 acetyl-CoA biosynthetic process 1/742 18/18722 0.517244225508069 0.67241749316049 ACSS1 1 GO:0006415 translational termination 1/742 18/18722 0.517244225508069 0.67241749316049 EIF5A 1 GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process 1/742 18/18722 0.517244225508069 0.67241749316049 NME3 1 GO:0010985 negative regulation of lipoprotein particle clearance 1/742 18/18722 0.517244225508069 0.67241749316049 LRPAP1 1 GO:0015693 magnesium ion transport 1/742 18/18722 0.517244225508069 0.67241749316049 TUSC3 1 GO:0015936 coenzyme A metabolic process 1/742 18/18722 0.517244225508069 0.67241749316049 CROT 1 GO:0019896 axonal transport of mitochondrion 1/742 18/18722 0.517244225508069 0.67241749316049 ARMCX3 1 GO:0021511 spinal cord patterning 1/742 18/18722 0.517244225508069 0.67241749316049 GLI3 1 GO:0030206 chondroitin sulfate biosynthetic process 1/742 18/18722 0.517244225508069 0.67241749316049 CHPF 1 GO:0030730 sequestering of triglyceride 1/742 18/18722 0.517244225508069 0.67241749316049 PLIN2 1 GO:0031643 positive regulation of myelination 1/742 18/18722 0.517244225508069 0.67241749316049 DAG1 1 GO:0031649 heat generation 1/742 18/18722 0.517244225508069 0.67241749316049 ADRB1 1 GO:0032634 interleukin-5 production 1/742 18/18722 0.517244225508069 0.67241749316049 GATA3 1 GO:0032674 regulation of interleukin-5 production 1/742 18/18722 0.517244225508069 0.67241749316049 GATA3 1 GO:0034162 toll-like receptor 9 signaling pathway 1/742 18/18722 0.517244225508069 0.67241749316049 RTN4 1 GO:0035372 protein localization to microtubule 1/742 18/18722 0.517244225508069 0.67241749316049 DIAPH1 1 GO:0036507 protein demannosylation 1/742 18/18722 0.517244225508069 0.67241749316049 MAN1A2 1 GO:0036508 protein alpha-1,2-demannosylation 1/742 18/18722 0.517244225508069 0.67241749316049 MAN1A2 1 GO:0042136 neurotransmitter biosynthetic process 1/742 18/18722 0.517244225508069 0.67241749316049 SLC6A4 1 GO:0043116 negative regulation of vascular permeability 1/742 18/18722 0.517244225508069 0.67241749316049 ADM 1 GO:0045116 protein neddylation 1/742 18/18722 0.517244225508069 0.67241749316049 EPAS1 1 GO:0045187 regulation of circadian sleep/wake cycle, sleep 1/742 18/18722 0.517244225508069 0.67241749316049 ADRB1 1 GO:0045623 negative regulation of T-helper cell differentiation 1/742 18/18722 0.517244225508069 0.67241749316049 ANXA1 1 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 1/742 18/18722 0.517244225508069 0.67241749316049 SERPINB9 1 GO:0045956 positive regulation of calcium ion-dependent exocytosis 1/742 18/18722 0.517244225508069 0.67241749316049 SYT7 1 GO:0048643 positive regulation of skeletal muscle tissue development 1/742 18/18722 0.517244225508069 0.67241749316049 IGF2 1 GO:0051447 negative regulation of meiotic cell cycle 1/742 18/18722 0.517244225508069 0.67241749316049 DUSP1 1 GO:0051895 negative regulation of focal adhesion assembly 1/742 18/18722 0.517244225508069 0.67241749316049 LRP1 1 GO:0055070 copper ion homeostasis 1/742 18/18722 0.517244225508069 0.67241749316049 APP 1 GO:0060391 positive regulation of SMAD protein signal transduction 1/742 18/18722 0.517244225508069 0.67241749316049 PARP1 1 GO:0060546 negative regulation of necroptotic process 1/742 18/18722 0.517244225508069 0.67241749316049 CAV1 1 GO:0071318 cellular response to ATP 1/742 18/18722 0.517244225508069 0.67241749316049 HSP90B1 1 GO:0071786 endoplasmic reticulum tubular network organization 1/742 18/18722 0.517244225508069 0.67241749316049 RTN4 1 GO:0071800 podosome assembly 1/742 18/18722 0.517244225508069 0.67241749316049 RHOA 1 GO:0072189 ureter development 1/742 18/18722 0.517244225508069 0.67241749316049 GATA3 1 GO:0097709 connective tissue replacement 1/742 18/18722 0.517244225508069 0.67241749316049 ROCK1 1 GO:0150078 positive regulation of neuroinflammatory response 1/742 18/18722 0.517244225508069 0.67241749316049 CTSC 1 GO:0150079 negative regulation of neuroinflammatory response 1/742 18/18722 0.517244225508069 0.67241749316049 GRN 1 GO:0150118 negative regulation of cell-substrate junction organization 1/742 18/18722 0.517244225508069 0.67241749316049 LRP1 1 GO:1902001 fatty acid transmembrane transport 1/742 18/18722 0.517244225508069 0.67241749316049 SLC2A1 1 GO:1902170 cellular response to reactive nitrogen species 1/742 18/18722 0.517244225508069 0.67241749316049 MTR 1 GO:1902683 regulation of receptor localization to synapse 1/742 18/18722 0.517244225508069 0.67241749316049 DAG1 1 GO:1904872 regulation of telomerase RNA localization to Cajal body 1/742 18/18722 0.517244225508069 0.67241749316049 CCT3 1 GO:1905820 positive regulation of chromosome separation 1/742 18/18722 0.517244225508069 0.67241749316049 ANAPC11 1 GO:0002287 alpha-beta T cell activation involved in immune response 3/742 69/18722 0.518749436942825 0.673134283818638 ANXA1/FOXP1/GATA3 3 GO:0002293 alpha-beta T cell differentiation involved in immune response 3/742 69/18722 0.518749436942825 0.673134283818638 ANXA1/FOXP1/GATA3 3 GO:0003143 embryonic heart tube morphogenesis 3/742 69/18722 0.518749436942825 0.673134283818638 FOLR1/CITED2/HES1 3 GO:0019226 transmission of nerve impulse 3/742 69/18722 0.518749436942825 0.673134283818638 PLEC/ANK3/JAM3 3 GO:0033344 cholesterol efflux 3/742 69/18722 0.518749436942825 0.673134283818638 LRP1/CAV1/NFKBIA 3 GO:0050688 regulation of defense response to virus 3/742 69/18722 0.518749436942825 0.673134283818638 TRIM44/EIF2AK4/PCBP2 3 GO:0070192 chromosome organization involved in meiotic cell cycle 3/742 69/18722 0.518749436942825 0.673134283818638 ATRX/RAD50/CCNE1 3 GO:0071774 response to fibroblast growth factor 5/742 120/18722 0.518921062719352 0.673180160145378 IER2/ZFP36L1/GPC1/KDM5B/GATA3 5 GO:0045580 regulation of T cell differentiation 6/742 146/18722 0.522558756352526 0.67772125397256 CD46/SOX4/ANXA1/GLI3/GATA3/RHOA 6 GO:0002532 production of molecular mediator involved in inflammatory response 4/742 95/18722 0.522925979688374 0.678019511721934 GRN/PLD3/CHID1/PDCD4 4 GO:0002066 columnar/cuboidal epithelial cell development 2/742 44/18722 0.525088642990528 0.680109569054329 IL6ST/CDK6 2 GO:0007528 neuromuscular junction development 2/742 44/18722 0.525088642990528 0.680109569054329 APP/ANK3 2 GO:0032881 regulation of polysaccharide metabolic process 2/742 44/18722 0.525088642990528 0.680109569054329 CLTC/IGF2 2 GO:0048066 developmental pigmentation 2/742 44/18722 0.525088642990528 0.680109569054329 GLI3/ATP6AP2 2 GO:0002274 myeloid leukocyte activation 9/742 223/18722 0.525754771664597 0.680793858983778 GRN/APP/JUND/CTSC/MIF/VAMP2/FOXP1/DHRS2/ANXA3 9 GO:0002224 toll-like receptor signaling pathway 5/742 121/18722 0.526317788492449 0.681344306905843 CAV1/LGR4/COLEC12/RTN4/NFKBIA 5 GO:0045123 cellular extravasation 3/742 70/18722 0.528491549176305 0.683979107396109 ITGB1/JAM3/ROCK1 3 GO:0002718 regulation of cytokine production involved in immune response 4/742 96/18722 0.531220558668649 0.684199155421541 CD81/CD55/DHX36/GATA3 4 GO:0035282 segmentation 4/742 96/18722 0.531220558668649 0.684199155421541 NRP2/PRKDC/NRP1/IRX2 4 GO:1901655 cellular response to ketone 4/742 96/18722 0.531220558668649 0.684199155421541 EGFR/ATP2B1/SERPINF1/LARP1 4 GO:0010469 regulation of signaling receptor activity 7/742 173/18722 0.531907412432828 0.684199155421541 AKAP9/APP/ITGB1/LRPAP1/NRP1/NCOA3/CGA 7 GO:0031109 microtubule polymerization or depolymerization 5/742 122/18722 0.533664304746506 0.684199155421541 AKAP9/MET/CLIP1/HSPA1A/HSPA1B 5 GO:0072329 monocarboxylic acid catabolic process 5/742 122/18722 0.533664304746506 0.684199155421541 SLC27A2/CROT/ACADVL/HADHA/ETFA 5 GO:0000028 ribosomal small subunit assembly 1/742 19/18722 0.53639546506501 0.684199155421541 PRKDC 1 GO:0002281 macrophage activation involved in immune response 1/742 19/18722 0.53639546506501 0.684199155421541 GRN 1 GO:0002396 MHC protein complex assembly 1/742 19/18722 0.53639546506501 0.684199155421541 CALR 1 GO:0002716 negative regulation of natural killer cell mediated immunity 1/742 19/18722 0.53639546506501 0.684199155421541 SERPINB9 1 GO:0002888 positive regulation of myeloid leukocyte mediated immunity 1/742 19/18722 0.53639546506501 0.684199155421541 DHX36 1 GO:0003085 negative regulation of systemic arterial blood pressure 1/742 19/18722 0.53639546506501 0.684199155421541 ADRB1 1 GO:0006044 N-acetylglucosamine metabolic process 1/742 19/18722 0.53639546506501 0.684199155421541 EXTL2 1 GO:0006071 glycerol metabolic process 1/742 19/18722 0.53639546506501 0.684199155421541 TPI1 1 GO:0007213 G protein-coupled acetylcholine receptor signaling pathway 1/742 19/18722 0.53639546506501 0.684199155421541 GNAQ 1 GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process 1/742 19/18722 0.53639546506501 0.684199155421541 NME3 1 GO:0010738 regulation of protein kinase A signaling 1/742 19/18722 0.53639546506501 0.684199155421541 MIF 1 GO:0019373 epoxygenase P450 pathway 1/742 19/18722 0.53639546506501 0.684199155421541 CYP2J2 1 GO:0030050 vesicle transport along actin filament 1/742 19/18722 0.53639546506501 0.684199155421541 ACTN4 1 GO:0030220 platelet formation 1/742 19/18722 0.53639546506501 0.684199155421541 PRKDC 1 GO:0031065 positive regulation of histone deacetylation 1/742 19/18722 0.53639546506501 0.684199155421541 NIPBL 1 GO:0032026 response to magnesium ion 1/742 19/18722 0.53639546506501 0.684199155421541 ANK3 1 GO:0032616 interleukin-13 production 1/742 19/18722 0.53639546506501 0.684199155421541 GATA3 1 GO:0032656 regulation of interleukin-13 production 1/742 19/18722 0.53639546506501 0.684199155421541 GATA3 1 GO:0035313 wound healing, spreading of epidermal cells 1/742 19/18722 0.53639546506501 0.684199155421541 FERMT1 1 GO:0036344 platelet morphogenesis 1/742 19/18722 0.53639546506501 0.684199155421541 PRKDC 1 GO:0038092 nodal signaling pathway 1/742 19/18722 0.53639546506501 0.684199155421541 CITED2 1 GO:0042474 middle ear morphogenesis 1/742 19/18722 0.53639546506501 0.684199155421541 NAGLU 1 GO:0043031 negative regulation of macrophage activation 1/742 19/18722 0.53639546506501 0.684199155421541 GRN 1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate 1/742 19/18722 0.53639546506501 0.684199155421541 MPHOSPH8 1 GO:0045603 positive regulation of endothelial cell differentiation 1/742 19/18722 0.53639546506501 0.684199155421541 BTG1 1 GO:0045618 positive regulation of keratinocyte differentiation 1/742 19/18722 0.53639546506501 0.684199155421541 NCOA3 1 GO:0045821 positive regulation of glycolytic process 1/742 19/18722 0.53639546506501 0.684199155421541 APP 1 GO:0046782 regulation of viral transcription 1/742 19/18722 0.53639546506501 0.684199155421541 RSF1 1 GO:0050961 detection of temperature stimulus involved in sensory perception 1/742 19/18722 0.53639546506501 0.684199155421541 NR2F6 1 GO:0051546 keratinocyte migration 1/742 19/18722 0.53639546506501 0.684199155421541 FERMT1 1 GO:0051571 positive regulation of histone H3-K4 methylation 1/742 19/18722 0.53639546506501 0.684199155421541 RTF1 1 GO:0051957 positive regulation of amino acid transport 1/742 19/18722 0.53639546506501 0.684199155421541 ITGB1 1 GO:0060039 pericardium development 1/742 19/18722 0.53639546506501 0.684199155421541 BMP7 1 GO:0062099 negative regulation of programmed necrotic cell death 1/742 19/18722 0.53639546506501 0.684199155421541 CAV1 1 GO:0070233 negative regulation of T cell apoptotic process 1/742 19/18722 0.53639546506501 0.684199155421541 DOCK8 1 GO:0070734 histone H3-K27 methylation 1/742 19/18722 0.53639546506501 0.684199155421541 GATA3 1 GO:0070989 oxidative demethylation 1/742 19/18722 0.53639546506501 0.684199155421541 TET2 1 GO:0072074 kidney mesenchyme development 1/742 19/18722 0.53639546506501 0.684199155421541 BMP7 1 GO:0090670 RNA localization to Cajal body 1/742 19/18722 0.53639546506501 0.684199155421541 CCT3 1 GO:0090671 telomerase RNA localization to Cajal body 1/742 19/18722 0.53639546506501 0.684199155421541 CCT3 1 GO:0090672 telomerase RNA localization 1/742 19/18722 0.53639546506501 0.684199155421541 CCT3 1 GO:0090685 RNA localization to nucleus 1/742 19/18722 0.53639546506501 0.684199155421541 CCT3 1 GO:0097501 stress response to metal ion 1/742 19/18722 0.53639546506501 0.684199155421541 HSPA5 1 GO:0097623 potassium ion export across plasma membrane 1/742 19/18722 0.53639546506501 0.684199155421541 DLG1 1 GO:1901881 positive regulation of protein depolymerization 1/742 19/18722 0.53639546506501 0.684199155421541 DSTN 1 GO:1903975 regulation of glial cell migration 1/742 19/18722 0.53639546506501 0.684199155421541 LRP1 1 GO:2000042 negative regulation of double-strand break repair via homologous recombination 1/742 19/18722 0.53639546506501 0.684199155421541 RIF1 1 GO:2000269 regulation of fibroblast apoptotic process 1/742 19/18722 0.53639546506501 0.684199155421541 BTG1 1 GO:2000369 regulation of clathrin-dependent endocytosis 1/742 19/18722 0.53639546506501 0.684199155421541 AAK1 1 GO:0002920 regulation of humoral immune response 2/742 45/18722 0.537248689044566 0.684199155421541 CD46/CD55 2 GO:0003009 skeletal muscle contraction 2/742 45/18722 0.537248689044566 0.684199155421541 GAA/GSTO1 2 GO:0006110 regulation of glycolytic process 2/742 45/18722 0.537248689044566 0.684199155421541 APP/NCOR1 2 GO:0006903 vesicle targeting 2/742 45/18722 0.537248689044566 0.684199155421541 TMED9/TRIP11 2 GO:0022602 ovulation cycle process 2/742 45/18722 0.537248689044566 0.684199155421541 HSPA5/ADAMTS1 2 GO:0031670 cellular response to nutrient 2/742 45/18722 0.537248689044566 0.684199155421541 ATP2B1/FOLR1 2 GO:0048546 digestive tract morphogenesis 2/742 45/18722 0.537248689044566 0.684199155421541 GLI3/NIPBL 2 GO:0032722 positive regulation of chemokine production 3/742 71/18722 0.538122855037436 0.684782819135737 LRP1/APP/EGR1 3 GO:0043550 regulation of lipid kinase activity 3/742 71/18722 0.538122855037436 0.684782819135737 FLT1/CD81/CDC42 3 GO:0045824 negative regulation of innate immune response 3/742 71/18722 0.538122855037436 0.684782819135737 GRN/ADAR/SERPINB9 3 GO:0099003 vesicle-mediated transport in synapse 8/742 200/18722 0.540063054965059 0.687074811106719 ACTG1/CANX/KIAA1109/ROCK1/SYT7/VAMP2/CALM1/RAB11A 8 GO:0031570 DNA integrity checkpoint signaling 5/742 123/18722 0.540958891962307 0.688037313669876 SOX4/RPL26/PRKDC/PPP1R10/EIF2AK4 5 GO:0032368 regulation of lipid transport 6/742 149/18722 0.542549545515667 0.68988281978054 LRP1/ITGAV/CAV1/KDM5B/NFKBIA/CYP19A1 6 GO:0002367 cytokine production involved in immune response 4/742 98/18722 0.547592560288739 0.69456863056532 CD81/CD55/DHX36/GATA3 4 GO:0032642 regulation of chemokine production 4/742 98/18722 0.547592560288739 0.69456863056532 LRP1/APP/EGR1/FOXP1 4 GO:0043473 pigmentation 4/742 98/18722 0.547592560288739 0.69456863056532 GLI3/ATP6AP2/NF1/RAB11A 4 GO:0070301 cellular response to hydrogen peroxide 4/742 98/18722 0.547592560288739 0.69456863056532 RHOB/MET/ANXA1/TXN 4 GO:0001736 establishment of planar polarity 3/742 72/18722 0.547640651022656 0.69456863056532 ZNRF3/CDC42/RHOA 3 GO:0002534 cytokine production involved in inflammatory response 3/742 72/18722 0.547640651022656 0.69456863056532 PLD3/CHID1/PDCD4 3 GO:0007164 establishment of tissue polarity 3/742 72/18722 0.547640651022656 0.69456863056532 ZNRF3/CDC42/RHOA 3 GO:0035567 non-canonical Wnt signaling pathway 3/742 72/18722 0.547640651022656 0.69456863056532 ZNRF3/CDC42/RHOA 3 GO:0050709 negative regulation of protein secretion 3/742 72/18722 0.547640651022656 0.69456863056532 ERP29/FRMD4A/ANXA1 3 GO:1900015 regulation of cytokine production involved in inflammatory response 3/742 72/18722 0.547640651022656 0.69456863056532 PLD3/CHID1/PDCD4 3 GO:0001959 regulation of cytokine-mediated signaling pathway 6/742 150/18722 0.549131702774113 0.695420566265875 CAV1/HSPA1A/TRIM44/HSPA1B/SPPL2B/ADAR 6 GO:0006383 transcription by RNA polymerase III 2/742 46/18722 0.549192357695371 0.695420566265875 BDP1/DHX36 2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 2/742 46/18722 0.549192357695371 0.695420566265875 TENM3/CADM1 2 GO:0031648 protein destabilization 2/742 46/18722 0.549192357695371 0.695420566265875 PRKDC/SIAH1 2 GO:0032924 activin receptor signaling pathway 2/742 46/18722 0.549192357695371 0.695420566265875 CITED2/CSNK2B 2 GO:0034198 cellular response to amino acid starvation 2/742 46/18722 0.549192357695371 0.695420566265875 SLC38A2/EIF2AK4 2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle 1/742 20/18722 0.554787945678909 0.695420566265875 BRD4 1 GO:0001832 blastocyst growth 1/742 20/18722 0.554787945678909 0.695420566265875 RTF1 1 GO:0006346 DNA methylation-dependent heterochromatin assembly 1/742 20/18722 0.554787945678909 0.695420566265875 MPHOSPH8 1 GO:0006448 regulation of translational elongation 1/742 20/18722 0.554787945678909 0.695420566265875 EIF5A 1 GO:0006837 serotonin transport 1/742 20/18722 0.554787945678909 0.695420566265875 SLC6A4 1 GO:0006851 mitochondrial calcium ion transmembrane transport 1/742 20/18722 0.554787945678909 0.695420566265875 VDAC1 1 GO:0007194 negative regulation of adenylate cyclase activity 1/742 20/18722 0.554787945678909 0.695420566265875 AKAP9 1 GO:0007620 copulation 1/742 20/18722 0.554787945678909 0.695420566265875 SLC6A4 1 GO:0009713 catechol-containing compound biosynthetic process 1/742 20/18722 0.554787945678909 0.695420566265875 GATA3 1 GO:0014047 glutamate secretion 1/742 20/18722 0.554787945678909 0.695420566265875 GJA1 1 GO:0015669 gas transport 1/742 20/18722 0.554787945678909 0.695420566265875 HBA2 1 GO:0021516 dorsal spinal cord development 1/742 20/18722 0.554787945678909 0.695420566265875 LMO4 1 GO:0031645 negative regulation of nervous system process 1/742 20/18722 0.554787945678909 0.695420566265875 CTSC 1 GO:0032495 response to muramyl dipeptide 1/742 20/18722 0.554787945678909 0.695420566265875 NFKBIA 1 GO:0032930 positive regulation of superoxide anion generation 1/742 20/18722 0.554787945678909 0.695420566265875 EGFR 1 GO:0034104 negative regulation of tissue remodeling 1/742 20/18722 0.554787945678909 0.695420566265875 CST3 1 GO:0039535 regulation of RIG-I signaling pathway 1/742 20/18722 0.554787945678909 0.695420566265875 PUM1 1 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate 1/742 20/18722 0.554787945678909 0.695420566265875 MPHOSPH8 1 GO:0042423 catecholamine biosynthetic process 1/742 20/18722 0.554787945678909 0.695420566265875 GATA3 1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process 1/742 20/18722 0.554787945678909 0.695420566265875 ITM2B 1 GO:0043011 myeloid dendritic cell differentiation 1/742 20/18722 0.554787945678909 0.695420566265875 DHRS2 1 GO:0043651 linoleic acid metabolic process 1/742 20/18722 0.554787945678909 0.695420566265875 CYP2J2 1 GO:0043984 histone H4-K16 acetylation 1/742 20/18722 0.554787945678909 0.695420566265875 PHF20 1 GO:0045063 T-helper 1 cell differentiation 1/742 20/18722 0.554787945678909 0.695420566265875 ANXA1 1 GO:0045844 positive regulation of striated muscle tissue development 1/742 20/18722 0.554787945678909 0.695420566265875 IGF2 1 GO:0046629 gamma-delta T cell activation 1/742 20/18722 0.554787945678909 0.695420566265875 SOX4 1 GO:0048636 positive regulation of muscle organ development 1/742 20/18722 0.554787945678909 0.695420566265875 IGF2 1 GO:0048670 regulation of collateral sprouting 1/742 20/18722 0.554787945678909 0.695420566265875 LRP1 1 GO:0051900 regulation of mitochondrial depolarization 1/742 20/18722 0.554787945678909 0.695420566265875 PARP1 1 GO:0060231 mesenchymal to epithelial transition 1/742 20/18722 0.554787945678909 0.695420566265875 GATA3 1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway 1/742 20/18722 0.554787945678909 0.695420566265875 ADAR 1 GO:0061003 positive regulation of dendritic spine morphogenesis 1/742 20/18722 0.554787945678909 0.695420566265875 DHX36 1 GO:0061318 renal filtration cell differentiation 1/742 20/18722 0.554787945678909 0.695420566265875 IQGAP1 1 GO:0071397 cellular response to cholesterol 1/742 20/18722 0.554787945678909 0.695420566265875 DAG1 1 GO:0071625 vocalization behavior 1/742 20/18722 0.554787945678909 0.695420566265875 GLI3 1 GO:0072112 glomerular visceral epithelial cell differentiation 1/742 20/18722 0.554787945678909 0.695420566265875 IQGAP1 1 GO:0090201 negative regulation of release of cytochrome c from mitochondria 1/742 20/18722 0.554787945678909 0.695420566265875 GPX1 1 GO:1901386 negative regulation of voltage-gated calcium channel activity 1/742 20/18722 0.554787945678909 0.695420566265875 CALM1 1 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/742 20/18722 0.554787945678909 0.695420566265875 HSPA1A 1 GO:2000479 regulation of cAMP-dependent protein kinase activity 1/742 20/18722 0.554787945678909 0.695420566265875 ATP2B4 1 GO:0021700 developmental maturation 11/742 280/18722 0.555245933587308 0.695462248244408 APP/DAG1/FERMT1/PFN1/ATP6AP2/RERE/DDIT3/GATA3/EPAS1/HES1/RHOA 11 GO:0002444 myeloid leukocyte mediated immunity 4/742 99/18722 0.555665889437385 0.695462248244408 VAMP2/DHX36/SERPINB9/ANXA3 4 GO:0015837 amine transport 4/742 99/18722 0.555665889437385 0.695462248244408 ITGB1/SLC43A2/ARL6IP5/SYT7 4 GO:0031341 regulation of cell killing 4/742 99/18722 0.555665889437385 0.695462248244408 CADM1/CD55/LAMP1/SERPINB9 4 GO:0032602 chemokine production 4/742 99/18722 0.555665889437385 0.695462248244408 LRP1/APP/EGR1/FOXP1 4 GO:0042100 B cell proliferation 4/742 99/18722 0.555665889437385 0.695462248244408 SLC39A10/TFRC/MIF/CD81 4 GO:0006644 phospholipid metabolic process 15/742 383/18722 0.556230413672982 0.695874654124292 PLPP3/SERINC1/PISD/GPAA1/SLC44A2/PGAP1/ISYNA1/CDS1/SERINC3/HADHA/PLBD1/PRDX6/CLN3/HEXB/GPX4 15 GO:0051648 vesicle localization 7/742 177/18722 0.556277127355633 0.695874654124292 DYNC1H1/TMED9/TRIP11/KIF5B/ACTN4/CLN3/RAB11A 7 GO:0002637 regulation of immunoglobulin production 3/742 73/18722 0.557042469146114 0.696126940951633 TFRC/PRKDC/RIF1 3 GO:0032456 endocytic recycling 3/742 73/18722 0.557042469146114 0.696126940951633 KIAA1109/CMTM6/RAB11A 3 GO:0043299 leukocyte degranulation 3/742 73/18722 0.557042469146114 0.696126940951633 VAMP2/LAMP1/ANXA3 3 GO:0051145 smooth muscle cell differentiation 3/742 73/18722 0.557042469146114 0.696126940951633 ADM/HES1/PDCD4 3 GO:0043547 positive regulation of GTPase activity 10/742 255/18722 0.558996339092079 0.698391986624904 ITGB1/ITGA6/NF1/ADRB1/RASA1/SYDE2/RABGAP1/DOCK8/S100A10/TGM2 10 GO:0001754 eye photoreceptor cell differentiation 2/742 47/18722 0.560917680132197 0.699200943692419 NAGLU/TUG1 2 GO:0007595 lactation 2/742 47/18722 0.560917680132197 0.699200943692419 CAV1/PRLR 2 GO:0035315 hair cell differentiation 2/742 47/18722 0.560917680132197 0.699200943692419 TRIOBP/HES1 2 GO:0035850 epithelial cell differentiation involved in kidney development 2/742 47/18722 0.560917680132197 0.699200943692419 IQGAP1/GATA3 2 GO:0043114 regulation of vascular permeability 2/742 47/18722 0.560917680132197 0.699200943692419 PLEC/ADM 2 GO:0045332 phospholipid translocation 2/742 47/18722 0.560917680132197 0.699200943692419 KCNN4/ATP10D 2 GO:0045581 negative regulation of T cell differentiation 2/742 47/18722 0.560917680132197 0.699200943692419 ANXA1/GLI3 2 GO:0101023 vascular endothelial cell proliferation 2/742 47/18722 0.560917680132197 0.699200943692419 FLT1/IGF2 2 GO:1905562 regulation of vascular endothelial cell proliferation 2/742 47/18722 0.560917680132197 0.699200943692419 FLT1/IGF2 2 GO:0031929 TOR signaling 5/742 126/18722 0.562515003570139 0.701015165902241 RPS6/SLC38A9/LARP1/GNA12/GATA3 5 GO:0002437 inflammatory response to antigenic stimulus 3/742 74/18722 0.566326068590823 0.703460534347065 CD81/GATA3/GPX1 3 GO:0006801 superoxide metabolic process 3/742 74/18722 0.566326068590823 0.703460534347065 EGFR/SOD3/BMP7 3 GO:0010822 positive regulation of mitochondrion organization 3/742 74/18722 0.566326068590823 0.703460534347065 PMAIP1/NMT1/VDAC1 3 GO:0006476 protein deacetylation 4/742 101/18722 0.57157788410355 0.703460534347065 KDM5A/NIPBL/TBL1X/MORF4L2 4 GO:0002673 regulation of acute inflammatory response 2/742 48/18722 0.572423182630901 0.703460534347065 IL6ST/ASH1L 2 GO:0042908 xenobiotic transport 2/742 48/18722 0.572423182630901 0.703460534347065 SLC2A1/GJA1 2 GO:0045005 DNA-dependent DNA replication maintenance of fidelity 2/742 48/18722 0.572423182630901 0.703460534347065 BOD1L1/ATRX 2 GO:0045912 negative regulation of carbohydrate metabolic process 2/742 48/18722 0.572423182630901 0.703460534347065 NCOR1/CLTC 2 GO:0090199 regulation of release of cytochrome c from mitochondria 2/742 48/18722 0.572423182630901 0.703460534347065 PMAIP1/GPX1 2 GO:0090311 regulation of protein deacetylation 2/742 48/18722 0.572423182630901 0.703460534347065 KDM5A/NIPBL 2 GO:1902003 regulation of amyloid-beta formation 2/742 48/18722 0.572423182630901 0.703460534347065 RTN4/ROCK1 2 GO:0003091 renal water homeostasis 1/742 21/18722 0.572451689893766 0.703460534347065 ATP6V1B1 1 GO:0003177 pulmonary valve development 1/742 21/18722 0.572451689893766 0.703460534347065 GJA5 1 GO:0006067 ethanol metabolic process 1/742 21/18722 0.572451689893766 0.703460534347065 ACSS1 1 GO:0006353 DNA-templated transcription, termination 1/742 21/18722 0.572451689893766 0.703460534347065 POLR2A 1 GO:0006450 regulation of translational fidelity 1/742 21/18722 0.572451689893766 0.703460534347065 IARS2 1 GO:0007063 regulation of sister chromatid cohesion 1/742 21/18722 0.572451689893766 0.703460534347065 ATRX 1 GO:0009067 aspartate family amino acid biosynthetic process 1/742 21/18722 0.572451689893766 0.703460534347065 MTR 1 GO:0009070 serine family amino acid biosynthetic process 1/742 21/18722 0.572451689893766 0.703460534347065 SERINC3 1 GO:0010988 regulation of low-density lipoprotein particle clearance 1/742 21/18722 0.572451689893766 0.703460534347065 CNPY2 1 GO:0019370 leukotriene biosynthetic process 1/742 21/18722 0.572451689893766 0.703460534347065 MGST3 1 GO:0019985 translesion synthesis 1/742 21/18722 0.572451689893766 0.703460534347065 USP10 1 GO:0022010 central nervous system myelination 1/742 21/18722 0.572451689893766 0.703460534347065 NCSTN 1 GO:0023019 signal transduction involved in regulation of gene expression 1/742 21/18722 0.572451689893766 0.703460534347065 PARP1 1 GO:0030502 negative regulation of bone mineralization 1/742 21/18722 0.572451689893766 0.703460534347065 LTBP3 1 GO:0032291 axon ensheathment in central nervous system 1/742 21/18722 0.572451689893766 0.703460534347065 NCSTN 1 GO:0033630 positive regulation of cell adhesion mediated by integrin 1/742 21/18722 0.572451689893766 0.703460534347065 FERMT1 1 GO:0033962 P-body assembly 1/742 21/18722 0.572451689893766 0.703460534347065 DYNC1H1 1 GO:0034312 diol biosynthetic process 1/742 21/18722 0.572451689893766 0.703460534347065 ASAH1 1 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation 1/742 21/18722 0.572451689893766 0.703460534347065 WASF2 1 GO:0034471 ncRNA 5'-end processing 1/742 21/18722 0.572451689893766 0.703460534347065 SSB 1 GO:0035020 regulation of Rac protein signal transduction 1/742 21/18722 0.572451689893766 0.703460534347065 DYNLT1 1 GO:0035330 regulation of hippo signaling 1/742 21/18722 0.572451689893766 0.703460534347065 DLG5 1 GO:0043373 CD4-positive, alpha-beta T cell lineage commitment 1/742 21/18722 0.572451689893766 0.703460534347065 CTSL 1 GO:0043576 regulation of respiratory gaseous exchange 1/742 21/18722 0.572451689893766 0.703460534347065 SLC5A3 1 GO:0044342 type B pancreatic cell proliferation 1/742 21/18722 0.572451689893766 0.703460534347065 SERPINB1 1 GO:0045717 negative regulation of fatty acid biosynthetic process 1/742 21/18722 0.572451689893766 0.703460534347065 ACADVL 1 GO:0046599 regulation of centriole replication 1/742 21/18722 0.572451689893766 0.703460534347065 NPM1 1 GO:0048199 vesicle targeting, to, from or within Golgi 1/742 21/18722 0.572451689893766 0.703460534347065 TMED9 1 GO:0048714 positive regulation of oligodendrocyte differentiation 1/742 21/18722 0.572451689893766 0.703460534347065 DAG1 1 GO:0050802 circadian sleep/wake cycle, sleep 1/742 21/18722 0.572451689893766 0.703460534347065 ADRB1 1 GO:0050849 negative regulation of calcium-mediated signaling 1/742 21/18722 0.572451689893766 0.703460534347065 ATP2B4 1 GO:0060117 auditory receptor cell development 1/742 21/18722 0.572451689893766 0.703460534347065 TRIOBP 1 GO:0060972 left/right pattern formation 1/742 21/18722 0.572451689893766 0.703460534347065 CITED2 1 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 1/742 21/18722 0.572451689893766 0.703460534347065 DHX36 1 GO:0070584 mitochondrion morphogenesis 1/742 21/18722 0.572451689893766 0.703460534347065 PLEC 1 GO:0072311 glomerular epithelial cell differentiation 1/742 21/18722 0.572451689893766 0.703460534347065 IQGAP1 1 GO:0090026 positive regulation of monocyte chemotaxis 1/742 21/18722 0.572451689893766 0.703460534347065 LGMN 1 GO:0097062 dendritic spine maintenance 1/742 21/18722 0.572451689893766 0.703460534347065 IGF1R 1 GO:0098719 sodium ion import across plasma membrane 1/742 21/18722 0.572451689893766 0.703460534347065 SLC9A1 1 GO:1901863 positive regulation of muscle tissue development 1/742 21/18722 0.572451689893766 0.703460534347065 IGF2 1 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1/742 21/18722 0.572451689893766 0.703460534347065 MIF 1 GO:1902644 tertiary alcohol metabolic process 1/742 21/18722 0.572451689893766 0.703460534347065 CYP11A1 1 GO:1903427 negative regulation of reactive oxygen species biosynthetic process 1/742 21/18722 0.572451689893766 0.703460534347065 RHOA 1 GO:1905209 positive regulation of cardiocyte differentiation 1/742 21/18722 0.572451689893766 0.703460534347065 DHX36 1 GO:2000291 regulation of myoblast proliferation 1/742 21/18722 0.572451689893766 0.703460534347065 MALAT1 1 GO:0034121 regulation of toll-like receptor signaling pathway 3/742 75/18722 0.575489427412213 0.707017600451711 CAV1/LGR4/RTN4 3 GO:0045833 negative regulation of lipid metabolic process 4/742 102/18722 0.579413176371029 0.711307428248728 ORMDL1/ATP1A1/NCOR1/ACADVL 4 GO:0062014 negative regulation of small molecule metabolic process 4/742 102/18722 0.579413176371029 0.711307428248728 ATP2B4/NCOR1/ACADVL/PARP1 4 GO:1902106 negative regulation of leukocyte differentiation 4/742 102/18722 0.579413176371029 0.711307428248728 FBN1/ANXA1/CDK6/GLI3 4 GO:0099504 synaptic vesicle cycle 7/742 181/18722 0.58007372892427 0.711764585416268 ACTG1/CANX/KIAA1109/ROCK1/SYT7/VAMP2/CALM1 7 GO:1905952 regulation of lipid localization 7/742 181/18722 0.58007372892427 0.711764585416268 LRP1/ITGAV/CAV1/PLIN2/KDM5B/NFKBIA/CYP19A1 7 GO:0006334 nucleosome assembly 5/742 129/18722 0.583548955457475 0.714272177724879 ATRX/NPM1/BRD2/HP1BP3/RSF1 5 GO:0002204 somatic recombination of immunoglobulin genes involved in immune response 2/742 49/18722 0.583707850501081 0.714272177724879 TFRC/RIF1 2 GO:0002208 somatic diversification of immunoglobulins involved in immune response 2/742 49/18722 0.583707850501081 0.714272177724879 TFRC/RIF1 2 GO:0002762 negative regulation of myeloid leukocyte differentiation 2/742 49/18722 0.583707850501081 0.714272177724879 FBN1/CDK6 2 GO:0009395 phospholipid catabolic process 2/742 49/18722 0.583707850501081 0.714272177724879 PLBD1/PRDX6 2 GO:0042304 regulation of fatty acid biosynthetic process 2/742 49/18722 0.583707850501081 0.714272177724879 ANXA1/ACADVL 2 GO:0042461 photoreceptor cell development 2/742 49/18722 0.583707850501081 0.714272177724879 NAGLU/TUG1 2 GO:0043457 regulation of cellular respiration 2/742 49/18722 0.583707850501081 0.714272177724879 IL10RB/RHOA 2 GO:0045190 isotype switching 2/742 49/18722 0.583707850501081 0.714272177724879 TFRC/RIF1 2 GO:0051445 regulation of meiotic cell cycle 2/742 49/18722 0.583707850501081 0.714272177724879 DUSP1/CALR 2 GO:1901799 negative regulation of proteasomal protein catabolic process 2/742 49/18722 0.583707850501081 0.714272177724879 EIF3H/SDCBP 2 GO:0006809 nitric oxide biosynthetic process 3/742 76/18722 0.58453073431237 0.714355431131303 CAV1/DYNLL1/ATP2B4 3 GO:0014855 striated muscle cell proliferation 3/742 76/18722 0.58453073431237 0.714355431131303 TGFBR3/GJA1/CITED2 3 GO:0032543 mitochondrial translation 3/742 76/18722 0.58453073431237 0.714355431131303 IARS2/TUFM/MRPS6 3 GO:0006836 neurotransmitter transport 8/742 208/18722 0.584820507080032 0.714355431131303 ITGB1/SLC38A1/SLC38A2/SLC6A4/PPP1R9A/SYT7/VAMP2/CALM1 8 GO:0009260 ribonucleotide biosynthetic process 7/742 182/18722 0.585926193305237 0.714355431131303 SLC26A2/ALDOA/ACSS1/TMSB4X/ENO1/NME3/PARP1 7 GO:0032760 positive regulation of tumor necrosis factor production 4/742 103/18722 0.587165940871762 0.714355431131303 APP/MIF/ISL1/HSPB1 4 GO:0002697 regulation of immune effector process 13/742 339/18722 0.588323662291369 0.714355431131303 CD46/GRN/CADM1/TFRC/PRKDC/CD81/ANXA1/CD55/LAMP1/DHX36/RIF1/GATA3/SERPINB9 13 GO:0002029 desensitization of G protein-coupled receptor signaling pathway 1/742 22/18722 0.589415533864614 0.714355431131303 ADM 1 GO:0002053 positive regulation of mesenchymal cell proliferation 1/742 22/18722 0.589415533864614 0.714355431131303 LRP5 1 GO:0002089 lens morphogenesis in camera-type eye 1/742 22/18722 0.589415533864614 0.714355431131303 CITED2 1 GO:0006359 regulation of transcription by RNA polymerase III 1/742 22/18722 0.589415533864614 0.714355431131303 DHX36 1 GO:0006662 glycerol ether metabolic process 1/742 22/18722 0.589415533864614 0.714355431131303 TXN 1 GO:0009220 pyrimidine ribonucleotide biosynthetic process 1/742 22/18722 0.589415533864614 0.714355431131303 NME3 1 GO:0014821 phasic smooth muscle contraction 1/742 22/18722 0.589415533864614 0.714355431131303 DLG1 1 GO:0019400 alditol metabolic process 1/742 22/18722 0.589415533864614 0.714355431131303 TPI1 1 GO:0021904 dorsal/ventral neural tube patterning 1/742 22/18722 0.589415533864614 0.714355431131303 GLI3 1 GO:0022401 negative adaptation of signaling pathway 1/742 22/18722 0.589415533864614 0.714355431131303 ADM 1 GO:0022616 DNA strand elongation 1/742 22/18722 0.589415533864614 0.714355431131303 RAD50 1 GO:0031281 positive regulation of cyclase activity 1/742 22/18722 0.589415533864614 0.714355431131303 NF1 1 GO:0032402 melanosome transport 1/742 22/18722 0.589415533864614 0.714355431131303 RAB11A 1 GO:0032700 negative regulation of interleukin-17 production 1/742 22/18722 0.589415533864614 0.714355431131303 DDIT3 1 GO:0032727 positive regulation of interferon-alpha production 1/742 22/18722 0.589415533864614 0.714355431131303 DHX36 1 GO:0032816 positive regulation of natural killer cell activation 1/742 22/18722 0.589415533864614 0.714355431131303 LAMP1 1 GO:0033617 mitochondrial cytochrome c oxidase assembly 1/742 22/18722 0.589415533864614 0.714355431131303 COX20 1 GO:0034755 iron ion transmembrane transport 1/742 22/18722 0.589415533864614 0.714355431131303 SLC40A1 1 GO:0035268 protein mannosylation 1/742 22/18722 0.589415533864614 0.714355431131303 B4GAT1 1 GO:0035584 calcium-mediated signaling using intracellular calcium source 1/742 22/18722 0.589415533864614 0.714355431131303 BCAP31 1 GO:0035809 regulation of urine volume 1/742 22/18722 0.589415533864614 0.714355431131303 ADM 1 GO:0042749 regulation of circadian sleep/wake cycle 1/742 22/18722 0.589415533864614 0.714355431131303 ADRB1 1 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation 1/742 22/18722 0.589415533864614 0.714355431131303 ANXA1 1 GO:0044346 fibroblast apoptotic process 1/742 22/18722 0.589415533864614 0.714355431131303 BTG1 1 GO:0045624 positive regulation of T-helper cell differentiation 1/742 22/18722 0.589415533864614 0.714355431131303 ANXA1 1 GO:0045663 positive regulation of myoblast differentiation 1/742 22/18722 0.589415533864614 0.714355431131303 BTG1 1 GO:0046628 positive regulation of insulin receptor signaling pathway 1/742 22/18722 0.589415533864614 0.714355431131303 IGF2 1 GO:0050860 negative regulation of T cell receptor signaling pathway 1/742 22/18722 0.589415533864614 0.714355431131303 PHPT1 1 GO:0051151 negative regulation of smooth muscle cell differentiation 1/742 22/18722 0.589415533864614 0.714355431131303 PDCD4 1 GO:0055093 response to hyperoxia 1/742 22/18722 0.589415533864614 0.714355431131303 CAV1 1 GO:0071467 cellular response to pH 1/742 22/18722 0.589415533864614 0.714355431131303 SLC9A1 1 GO:0086012 membrane depolarization during cardiac muscle cell action potential 1/742 22/18722 0.589415533864614 0.714355431131303 ANK3 1 GO:0006282 regulation of DNA repair 5/742 130/18722 0.59043808665532 0.715243783246023 EGFR/FUS/PRKDC/RIF1/PARP1 5 GO:0043467 regulation of generation of precursor metabolites and energy 5/742 130/18722 0.59043808665532 0.715243783246023 APP/IL10RB/NCOR1/RHOA/IGF2 5 GO:0070646 protein modification by small protein removal 6/742 157/18722 0.593941514048169 0.718730236029389 USP9X/USP27X/USP22/USP48/USP10/EIF3F 6 GO:0000387 spliceosomal snRNP assembly 2/742 50/18722 0.594771094106912 0.718730236029389 SNRPD2/SNRPC 2 GO:0002639 positive regulation of immunoglobulin production 2/742 50/18722 0.594771094106912 0.718730236029389 TFRC/RIF1 2 GO:0007080 mitotic metaphase plate congression 2/742 50/18722 0.594771094106912 0.718730236029389 KPNB1/RAB11A 2 GO:0008089 anterograde axonal transport 2/742 50/18722 0.594771094106912 0.718730236029389 KIF5B/HSPB1 2 GO:0019083 viral transcription 2/742 50/18722 0.594771094106912 0.718730236029389 JUN/RSF1 2 GO:0030490 maturation of SSU-rRNA 2/742 50/18722 0.594771094106912 0.718730236029389 RPS21/RPS16 2 GO:0043628 ncRNA 3'-end processing 2/742 50/18722 0.594771094106912 0.718730236029389 RPS21/SSB 2 GO:0045814 negative regulation of gene expression, epigenetic 2/742 50/18722 0.594771094106912 0.718730236029389 MPHOSPH8/TPR 2 GO:1902930 regulation of alcohol biosynthetic process 2/742 50/18722 0.594771094106912 0.718730236029389 POR/MBTPS1 2 GO:0032102 negative regulation of response to external stimulus 16/742 420/18722 0.600693518109352 0.723976153022629 GRN/SEMA6A/SERPINF1/DUSP1/MIF/SEMA6D/GJA1/DPP4/NRP1/ISL1/ASH1L/PCBP2/GATA3/ADAR/GPX1/SERPINB9 16 GO:0032371 regulation of sterol transport 3/742 78/18722 0.60224095166075 0.723976153022629 LRP1/CAV1/NFKBIA 3 GO:0032374 regulation of cholesterol transport 3/742 78/18722 0.60224095166075 0.723976153022629 LRP1/CAV1/NFKBIA 3 GO:0035050 embryonic heart tube development 3/742 78/18722 0.60224095166075 0.723976153022629 FOLR1/CITED2/HES1 3 GO:0043537 negative regulation of blood vessel endothelial cell migration 3/742 78/18722 0.60224095166075 0.723976153022629 ATP2B4/RHOA/CSNK2B 3 GO:0090049 regulation of cell migration involved in sprouting angiogenesis 3/742 78/18722 0.60224095166075 0.723976153022629 NRP1/ANXA1/RHOA 3 GO:0032496 response to lipopolysaccharide 13/742 343/18722 0.605348706402428 0.723976153022629 JUN/FOS/JUND/GJA1/PABPN1/S100A9/CD55/ADM/FOXP1/NFKBIA/RHOA/HPGD/PDCD4 13 GO:0009584 detection of visible light 2/742 51/18722 0.605612716854263 0.723976153022629 NMT1/GNAQ 2 GO:0010656 negative regulation of muscle cell apoptotic process 2/742 51/18722 0.605612716854263 0.723976153022629 PPP1R10/BMP7 2 GO:0032964 collagen biosynthetic process 2/742 51/18722 0.605612716854263 0.723976153022629 SERPINH1/SUCO 2 GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 2/742 51/18722 0.605612716854263 0.723976153022629 ANXA1/GATA3 2 GO:0048013 ephrin receptor signaling pathway 2/742 51/18722 0.605612716854263 0.723976153022629 EPHB4/RASA1 2 GO:0071622 regulation of granulocyte chemotaxis 2/742 51/18722 0.605612716854263 0.723976153022629 DPP4/JAM3 2 GO:1903307 positive regulation of regulated secretory pathway 2/742 51/18722 0.605612716854263 0.723976153022629 SYT7/LAMP1 2 GO:0000966 RNA 5'-end processing 1/742 23/18722 0.605707174178649 0.723976153022629 SSB 1 GO:0002052 positive regulation of neuroblast proliferation 1/742 23/18722 0.605707174178649 0.723976153022629 GLI3 1 GO:0002082 regulation of oxidative phosphorylation 1/742 23/18722 0.605707174178649 0.723976153022629 RHOA 1 GO:0003323 type B pancreatic cell development 1/742 23/18722 0.605707174178649 0.723976153022629 CDK6 1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules 1/742 23/18722 0.605707174178649 0.723976153022629 CLDN4 1 GO:0016578 histone deubiquitination 1/742 23/18722 0.605707174178649 0.723976153022629 USP22 1 GO:0021544 subpallium development 1/742 23/18722 0.605707174178649 0.723976153022629 GLI3 1 GO:0023058 adaptation of signaling pathway 1/742 23/18722 0.605707174178649 0.723976153022629 ADM 1 GO:0031280 negative regulation of cyclase activity 1/742 23/18722 0.605707174178649 0.723976153022629 AKAP9 1 GO:0032401 establishment of melanosome localization 1/742 23/18722 0.605707174178649 0.723976153022629 RAB11A 1 GO:0034105 positive regulation of tissue remodeling 1/742 23/18722 0.605707174178649 0.723976153022629 ROCK1 1 GO:0034695 response to prostaglandin E 1/742 23/18722 0.605707174178649 0.723976153022629 TGFBR3 1 GO:0035640 exploration behavior 1/742 23/18722 0.605707174178649 0.723976153022629 DPP4 1 GO:0035812 renal sodium excretion 1/742 23/18722 0.605707174178649 0.723976153022629 ATP6V1B1 1 GO:0035988 chondrocyte proliferation 1/742 23/18722 0.605707174178649 0.723976153022629 GOLGB1 1 GO:0040019 positive regulation of embryonic development 1/742 23/18722 0.605707174178649 0.723976153022629 CFL1 1 GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment 1/742 23/18722 0.605707174178649 0.723976153022629 CTSL 1 GO:0043931 ossification involved in bone maturation 1/742 23/18722 0.605707174178649 0.723976153022629 RHOA 1 GO:0045723 positive regulation of fatty acid biosynthetic process 1/742 23/18722 0.605707174178649 0.723976153022629 ANXA1 1 GO:0051349 positive regulation of lyase activity 1/742 23/18722 0.605707174178649 0.723976153022629 NF1 1 GO:0051590 positive regulation of neurotransmitter transport 1/742 23/18722 0.605707174178649 0.723976153022629 ITGB1 1 GO:0051882 mitochondrial depolarization 1/742 23/18722 0.605707174178649 0.723976153022629 PARP1 1 GO:0051904 pigment granule transport 1/742 23/18722 0.605707174178649 0.723976153022629 RAB11A 1 GO:0060547 negative regulation of necrotic cell death 1/742 23/18722 0.605707174178649 0.723976153022629 CAV1 1 GO:0060575 intestinal epithelial cell differentiation 1/742 23/18722 0.605707174178649 0.723976153022629 IL6ST 1 GO:0061050 regulation of cell growth involved in cardiac muscle cell development 1/742 23/18722 0.605707174178649 0.723976153022629 YY1 1 GO:0071218 cellular response to misfolded protein 1/742 23/18722 0.605707174178649 0.723976153022629 DNAJB14 1 GO:0071305 cellular response to vitamin D 1/742 23/18722 0.605707174178649 0.723976153022629 ATP2B1 1 GO:0071514 genetic imprinting 1/742 23/18722 0.605707174178649 0.723976153022629 IGF2 1 GO:0090335 regulation of brown fat cell differentiation 1/742 23/18722 0.605707174178649 0.723976153022629 BMP7 1 GO:1902410 mitotic cytokinetic process 1/742 23/18722 0.605707174178649 0.723976153022629 RHOA 1 GO:0051607 defense response to virus 10/742 265/18722 0.608015691831124 0.726383922042504 IL10RB/TRIM44/PMAIP1/PUM1/DDX17/SERINC3/DHX36/EIF2AK4/PCBP2/ADAR 10 GO:0140546 defense response to symbiont 10/742 265/18722 0.608015691831124 0.726383922042504 IL10RB/TRIM44/PMAIP1/PUM1/DDX17/SERINC3/DHX36/EIF2AK4/PCBP2/ADAR 10 GO:1902115 regulation of organelle assembly 7/742 186/18722 0.608924037241893 0.727293216628373 DYNC1H1/NPM1/TPR/HSPA1A/HSPA1B/RHOA/SDCBP 7 GO:1903707 negative regulation of hemopoiesis 4/742 106/18722 0.609915566501313 0.728301401623516 FBN1/ANXA1/CDK6/GLI3 4 GO:0006997 nucleus organization 5/742 133/18722 0.610722898682599 0.72891305133898 SF1/PLEC/RTN4/TPR/NEK6 5 GO:0009855 determination of bilateral symmetry 5/742 133/18722 0.610722898682599 0.72891305133898 GALNT11/FOLR1/DDIT3/TMEM107/CITED2 5 GO:0001895 retina homeostasis 3/742 79/18722 0.610907220020966 0.728956924372843 SLC2A1/ACTG1/HSPB1 3 GO:0001505 regulation of neurotransmitter levels 8/742 213/18722 0.611715377885725 0.729744981104922 ITGB1/SLC38A1/SLC6A4/PPP1R9A/SYT7/VAMP2/CALM1/CLN3 8 GO:0010662 regulation of striated muscle cell apoptotic process 2/742 52/18722 0.616232885041955 0.733975339881614 PPP1R10/BMP7 2 GO:0034204 lipid translocation 2/742 52/18722 0.616232885041955 0.733975339881614 KCNN4/ATP10D 2 GO:0035176 social behavior 2/742 52/18722 0.616232885041955 0.733975339881614 SLC6A4/PCM1 2 GO:0072132 mesenchyme morphogenesis 2/742 52/18722 0.616232885041955 0.733975339881614 BMP7/ISL1 2 GO:1903426 regulation of reactive oxygen species biosynthetic process 2/742 52/18722 0.616232885041955 0.733975339881614 SLC5A3/RHOA 2 GO:2000378 negative regulation of reactive oxygen species metabolic process 2/742 52/18722 0.616232885041955 0.733975339881614 VDAC1/RHOA 2 GO:0032526 response to retinoic acid 4/742 107/18722 0.617325248642075 0.733975339881614 SERPINF1/DUSP1/GJA1/SLC6A4 4 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 4/742 107/18722 0.617325248642075 0.733975339881614 APP/MIF/ISL1/HSPB1 4 GO:0009799 specification of symmetry 5/742 134/18722 0.617353606926897 0.733975339881614 GALNT11/FOLR1/DDIT3/TMEM107/CITED2 5 GO:0051303 establishment of chromosome localization 3/742 80/18722 0.619446136566351 0.733975339881614 DYNC1H1/KPNB1/RAB11A 3 GO:0000395 mRNA 5'-splice site recognition 1/742 24/18722 0.621353212830953 0.733975339881614 SNRPC 1 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/742 24/18722 0.621353212830953 0.733975339881614 RPS21 1 GO:0001702 gastrulation with mouth forming second 1/742 24/18722 0.621353212830953 0.733975339881614 LRP5 1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity 1/742 24/18722 0.621353212830953 0.733975339881614 SERPINB9 1 GO:0002021 response to dietary excess 1/742 24/18722 0.621353212830953 0.733975339881614 ADRB1 1 GO:0002438 acute inflammatory response to antigenic stimulus 1/742 24/18722 0.621353212830953 0.733975339881614 GATA3 1 GO:0003181 atrioventricular valve morphogenesis 1/742 24/18722 0.621353212830953 0.733975339881614 SOX4 1 GO:0010288 response to lead ion 1/742 24/18722 0.621353212830953 0.733975339881614 APP 1 GO:0016048 detection of temperature stimulus 1/742 24/18722 0.621353212830953 0.733975339881614 NR2F6 1 GO:0022410 circadian sleep/wake cycle process 1/742 24/18722 0.621353212830953 0.733975339881614 ADRB1 1 GO:0030878 thyroid gland development 1/742 24/18722 0.621353212830953 0.733975339881614 CGA 1 GO:0032928 regulation of superoxide anion generation 1/742 24/18722 0.621353212830953 0.733975339881614 EGFR 1 GO:0033032 regulation of myeloid cell apoptotic process 1/742 24/18722 0.621353212830953 0.733975339881614 ANXA1 1 GO:0036010 protein localization to endosome 1/742 24/18722 0.621353212830953 0.733975339881614 NRP1 1 GO:0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 1/742 24/18722 0.621353212830953 0.733975339881614 PUM1 1 GO:0043302 positive regulation of leukocyte degranulation 1/742 24/18722 0.621353212830953 0.733975339881614 LAMP1 1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 1/742 24/18722 0.621353212830953 0.733975339881614 PHIP 1 GO:0044321 response to leptin 1/742 24/18722 0.621353212830953 0.733975339881614 LRP2 1 GO:0048641 regulation of skeletal muscle tissue development 1/742 24/18722 0.621353212830953 0.733975339881614 IGF2 1 GO:0050687 negative regulation of defense response to virus 1/742 24/18722 0.621353212830953 0.733975339881614 PCBP2 1 GO:0051000 positive regulation of nitric-oxide synthase activity 1/742 24/18722 0.621353212830953 0.733975339881614 CALM1 1 GO:0051905 establishment of pigment granule localization 1/742 24/18722 0.621353212830953 0.733975339881614 RAB11A 1 GO:0051923 sulfation 1/742 24/18722 0.621353212830953 0.733975339881614 TPST2 1 GO:0060571 morphogenesis of an epithelial fold 1/742 24/18722 0.621353212830953 0.733975339881614 BMP7 1 GO:0070935 3'-UTR-mediated mRNA stabilization 1/742 24/18722 0.621353212830953 0.733975339881614 HNRNPC 1 GO:0071294 cellular response to zinc ion 1/742 24/18722 0.621353212830953 0.733975339881614 PARP1 1 GO:0072010 glomerular epithelium development 1/742 24/18722 0.621353212830953 0.733975339881614 IQGAP1 1 GO:0072530 purine-containing compound transmembrane transport 1/742 24/18722 0.621353212830953 0.733975339881614 SLC19A1 1 GO:1903428 positive regulation of reactive oxygen species biosynthetic process 1/742 24/18722 0.621353212830953 0.733975339881614 SLC5A3 1 GO:2000310 regulation of NMDA receptor activity 1/742 24/18722 0.621353212830953 0.733975339881614 APP 1 GO:2000353 positive regulation of endothelial cell apoptotic process 1/742 24/18722 0.621353212830953 0.733975339881614 PDCD4 1 GO:0060759 regulation of response to cytokine stimulus 6/742 162/18722 0.624459071374629 0.737336535662546 CAV1/HSPA1A/TRIM44/HSPA1B/SPPL2B/ADAR 6 GO:0002832 negative regulation of response to biotic stimulus 4/742 108/18722 0.62464643760076 0.737336535662546 GRN/PCBP2/ADAR/SERPINB9 4 GO:0007173 epidermal growth factor receptor signaling pathway 4/742 108/18722 0.62464643760076 0.737336535662546 EGFR/EFEMP1/IQGAP1/PTPN12 4 GO:0016925 protein sumoylation 2/742 53/18722 0.626632099480003 0.739150566244321 EGR1/RANBP2 2 GO:0034381 plasma lipoprotein particle clearance 2/742 53/18722 0.626632099480003 0.739150566244321 LRPAP1/CNPY2 2 GO:0043113 receptor clustering 2/742 53/18722 0.626632099480003 0.739150566244321 CD81/DLG1 2 GO:0008589 regulation of smoothened signaling pathway 3/742 81/18722 0.627856823375681 0.740241696294955 DLG5/POR/GLI3 3 GO:0021954 central nervous system neuron development 3/742 81/18722 0.627856823375681 0.740241696294955 NRP2/MYCBP2/NRP1 3 GO:0001910 regulation of leukocyte mediated cytotoxicity 3/742 82/18722 0.63613856610836 0.742996498295991 CADM1/LAMP1/SERPINB9 3 GO:0007032 endosome organization 3/742 82/18722 0.63613856610836 0.742996498295991 EEA1/HOOK2/RAB11A 3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 3/742 82/18722 0.63613856610836 0.742996498295991 PMAIP1/TIMP3/GPX1 3 GO:0050000 chromosome localization 3/742 82/18722 0.63613856610836 0.742996498295991 DYNC1H1/KPNB1/RAB11A 3 GO:0072527 pyrimidine-containing compound metabolic process 3/742 82/18722 0.63613856610836 0.742996498295991 SLC19A3/TET2/NME3 3 GO:0006312 mitotic recombination 1/742 25/18722 0.636379200427458 0.742996498295991 RAD50 1 GO:0007274 neuromuscular synaptic transmission 1/742 25/18722 0.636379200427458 0.742996498295991 ERC1 1 GO:0009147 pyrimidine nucleoside triphosphate metabolic process 1/742 25/18722 0.636379200427458 0.742996498295991 NME3 1 GO:0010842 retina layer formation 1/742 25/18722 0.636379200427458 0.742996498295991 OBSL1 1 GO:0010954 positive regulation of protein processing 1/742 25/18722 0.636379200427458 0.742996498295991 ENO1 1 GO:0030318 melanocyte differentiation 1/742 25/18722 0.636379200427458 0.742996498295991 GLI3 1 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 1/742 25/18722 0.636379200427458 0.742996498295991 CD55 1 GO:0032400 melanosome localization 1/742 25/18722 0.636379200427458 0.742996498295991 RAB11A 1 GO:0032753 positive regulation of interleukin-4 production 1/742 25/18722 0.636379200427458 0.742996498295991 GATA3 1 GO:0032925 regulation of activin receptor signaling pathway 1/742 25/18722 0.636379200427458 0.742996498295991 CSNK2B 1 GO:0033233 regulation of protein sumoylation 1/742 25/18722 0.636379200427458 0.742996498295991 EGR1 1 GO:0035902 response to immobilization stress 1/742 25/18722 0.636379200427458 0.742996498295991 FOS 1 GO:0036315 cellular response to sterol 1/742 25/18722 0.636379200427458 0.742996498295991 DAG1 1 GO:0045324 late endosome to vacuole transport 1/742 25/18722 0.636379200427458 0.742996498295991 LEPROT 1 GO:0045822 negative regulation of heart contraction 1/742 25/18722 0.636379200427458 0.742996498295991 ATP1A1 1 GO:0046835 carbohydrate phosphorylation 1/742 25/18722 0.636379200427458 0.742996498295991 GNPTAB 1 GO:0050951 sensory perception of temperature stimulus 1/742 25/18722 0.636379200427458 0.742996498295991 NR2F6 1 GO:0051204 protein insertion into mitochondrial membrane 1/742 25/18722 0.636379200427458 0.742996498295991 NMT1 1 GO:0051788 response to misfolded protein 1/742 25/18722 0.636379200427458 0.742996498295991 DNAJB14 1 GO:0060074 synapse maturation 1/742 25/18722 0.636379200427458 0.742996498295991 PFN1 1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 1/742 25/18722 0.636379200427458 0.742996498295991 DHX36 1 GO:0060740 prostate gland epithelium morphogenesis 1/742 25/18722 0.636379200427458 0.742996498295991 BMP7 1 GO:0062149 detection of stimulus involved in sensory perception of pain 1/742 25/18722 0.636379200427458 0.742996498295991 NR2F6 1 GO:0072202 cell differentiation involved in metanephros development 1/742 25/18722 0.636379200427458 0.742996498295991 LGR4 1 GO:0090312 positive regulation of protein deacetylation 1/742 25/18722 0.636379200427458 0.742996498295991 NIPBL 1 GO:0090330 regulation of platelet aggregation 1/742 25/18722 0.636379200427458 0.742996498295991 IL6ST 1 GO:0098703 calcium ion import across plasma membrane 1/742 25/18722 0.636379200427458 0.742996498295991 ATP2B4 1 GO:0099560 synaptic membrane adhesion 1/742 25/18722 0.636379200427458 0.742996498295991 PTPRF 1 GO:1902932 positive regulation of alcohol biosynthetic process 1/742 25/18722 0.636379200427458 0.742996498295991 POR 1 GO:1903055 positive regulation of extracellular matrix organization 1/742 25/18722 0.636379200427458 0.742996498295991 DAG1 1 GO:1903901 negative regulation of viral life cycle 1/742 25/18722 0.636379200427458 0.742996498295991 PPIA 1 GO:1905563 negative regulation of vascular endothelial cell proliferation 1/742 25/18722 0.636379200427458 0.742996498295991 FLT1 1 GO:1905564 positive regulation of vascular endothelial cell proliferation 1/742 25/18722 0.636379200427458 0.742996498295991 IGF2 1 GO:0006164 purine nucleotide biosynthetic process 7/742 191/18722 0.636689767477142 0.742996498295991 SLC26A2/ALDOA/ACSS1/TMSB4X/ENO1/NME3/PARP1 7 GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2/742 54/18722 0.636811168782434 0.742996498295991 CD46/CD55 2 GO:0006584 catecholamine metabolic process 2/742 54/18722 0.636811168782434 0.742996498295991 GATA3/EPAS1 2 GO:0006968 cellular defense response 2/742 54/18722 0.636811168782434 0.742996498295991 ITGB1/LGALS3BP 2 GO:0009712 catechol-containing compound metabolic process 2/742 54/18722 0.636811168782434 0.742996498295991 GATA3/EPAS1 2 GO:0051703 biological process involved in intraspecies interaction between organisms 2/742 54/18722 0.636811168782434 0.742996498295991 SLC6A4/PCM1 2 GO:0018958 phenol-containing compound metabolic process 4/742 110/18722 0.639019867178845 0.745221469278445 CPQ/GATA3/EPAS1/CGA 4 GO:0048259 regulation of receptor-mediated endocytosis 4/742 110/18722 0.639019867178845 0.745221469278445 ITGAV/LRPAP1/AAK1/SDCBP 4 GO:0000724 double-strand break repair via homologous recombination 5/742 138/18722 0.643198859099576 0.749741001404414 FUS/NIPBL/RIF1/PARP1/YY1 5 GO:0007224 smoothened signaling pathway 5/742 138/18722 0.643198859099576 0.749741001404414 DLG5/POR/GLI3/IFT27/HES1 5 GO:0006066 alcohol metabolic process 13/742 353/18722 0.64643080423842 0.752398738067755 APP/ACSS1/DHCR24/PLPP3/LRP5/POR/TPI1/SLC5A3/ISYNA1/MBTPS1/ACADVL/ASAH1/CYP11A1 13 GO:0002067 glandular epithelial cell differentiation 2/742 55/18722 0.646771184246809 0.752398738067755 CDK6/HES1 2 GO:0008333 endosome to lysosome transport 2/742 55/18722 0.646771184246809 0.752398738067755 RHOB/HOOK2 2 GO:0042220 response to cocaine 2/742 55/18722 0.646771184246809 0.752398738067755 HSPA5/TGM2 2 GO:0045620 negative regulation of lymphocyte differentiation 2/742 55/18722 0.646771184246809 0.752398738067755 ANXA1/GLI3 2 GO:1902991 regulation of amyloid precursor protein catabolic process 2/742 55/18722 0.646771184246809 0.752398738067755 RTN4/ROCK1 2 GO:1905517 macrophage migration 2/742 55/18722 0.646771184246809 0.752398738067755 MIF/CD81 2 GO:0002831 regulation of response to biotic stimulus 12/742 327/18722 0.648567734844207 0.752398738067755 GRN/CADM1/PRKDC/TRIM44/CD55/PUM1/FOXP1/LAMP1/EIF2AK4/PCBP2/ADAR/SERPINB9 12 GO:0001963 synaptic transmission, dopaminergic 1/742 26/18722 0.650809677684923 0.752398738067755 SLC6A4 1 GO:0002407 dendritic cell chemotaxis 1/742 26/18722 0.650809677684923 0.752398738067755 CALR 1 GO:0003416 endochondral bone growth 1/742 26/18722 0.650809677684923 0.752398738067755 POR 1 GO:0006706 steroid catabolic process 1/742 26/18722 0.650809677684923 0.752398738067755 CYP19A1 1 GO:0007214 gamma-aminobutyric acid signaling pathway 1/742 26/18722 0.650809677684923 0.752398738067755 GABRE 1 GO:0008535 respiratory chain complex IV assembly 1/742 26/18722 0.650809677684923 0.752398738067755 COX20 1 GO:0018027 peptidyl-lysine dimethylation 1/742 26/18722 0.650809677684923 0.752398738067755 ASH1L 1 GO:0021952 central nervous system projection neuron axonogenesis 1/742 26/18722 0.650809677684923 0.752398738067755 MYCBP2 1 GO:0034114 regulation of heterotypic cell-cell adhesion 1/742 26/18722 0.650809677684923 0.752398738067755 BMP7 1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated 1/742 26/18722 0.650809677684923 0.752398738067755 ARMCX3 1 GO:0047497 mitochondrion transport along microtubule 1/742 26/18722 0.650809677684923 0.752398738067755 ARMCX3 1 GO:0051875 pigment granule localization 1/742 26/18722 0.650809677684923 0.752398738067755 RAB11A 1 GO:0060219 camera-type eye photoreceptor cell differentiation 1/742 26/18722 0.650809677684923 0.752398738067755 NAGLU 1 GO:0060544 regulation of necroptotic process 1/742 26/18722 0.650809677684923 0.752398738067755 CAV1 1 GO:0070102 interleukin-6-mediated signaling pathway 1/742 26/18722 0.650809677684923 0.752398738067755 IL6ST 1 GO:0070977 bone maturation 1/742 26/18722 0.650809677684923 0.752398738067755 RHOA 1 GO:0071425 hematopoietic stem cell proliferation 1/742 26/18722 0.650809677684923 0.752398738067755 N4BP2L2 1 GO:0097066 response to thyroid hormone 1/742 26/18722 0.650809677684923 0.752398738067755 CTSL 1 GO:0097186 amelogenesis 1/742 26/18722 0.650809677684923 0.752398738067755 CSF3R 1 GO:1901071 glucosamine-containing compound metabolic process 1/742 26/18722 0.650809677684923 0.752398738067755 EXTL2 1 GO:1902186 regulation of viral release from host cell 1/742 26/18722 0.650809677684923 0.752398738067755 DDB1 1 GO:1902656 calcium ion import into cytosol 1/742 26/18722 0.650809677684923 0.752398738067755 ATP2B4 1 GO:1903523 negative regulation of blood circulation 1/742 26/18722 0.650809677684923 0.752398738067755 ATP1A1 1 GO:1904353 regulation of telomere capping 1/742 26/18722 0.650809677684923 0.752398738067755 RAD50 1 GO:1905063 regulation of vascular associated smooth muscle cell differentiation 1/742 26/18722 0.650809677684923 0.752398738067755 PDCD4 1 GO:2000050 regulation of non-canonical Wnt signaling pathway 1/742 26/18722 0.650809677684923 0.752398738067755 ZNRF3 1 GO:2000108 positive regulation of leukocyte apoptotic process 1/742 26/18722 0.650809677684923 0.752398738067755 ANXA1 1 GO:0010660 regulation of muscle cell apoptotic process 3/742 84/18722 0.652313135878111 0.753784068125817 PPP1R10/BMP7/PDCD4 3 GO:0098586 cellular response to virus 3/742 84/18722 0.652313135878111 0.753784068125817 PUM1/ADAR/EIF5A 3 GO:0000725 recombinational repair 5/742 140/18722 0.655704954817696 0.757044040945461 FUS/NIPBL/RIF1/PARP1/YY1 5 GO:0015748 organophosphate ester transport 5/742 140/18722 0.655704954817696 0.757044040945461 KCNN4/GJA1/SLC19A1/SLC25A36/ATP10D 5 GO:0046165 alcohol biosynthetic process 5/742 140/18722 0.655704954817696 0.757044040945461 DHCR24/POR/ISYNA1/MBTPS1/ASAH1 5 GO:0001912 positive regulation of leukocyte mediated cytotoxicity 2/742 56/18722 0.656513496236914 0.757044040945461 CADM1/LAMP1 2 GO:0002090 regulation of receptor internalization 2/742 56/18722 0.656513496236914 0.757044040945461 LRPAP1/SDCBP 2 GO:0010658 striated muscle cell apoptotic process 2/742 56/18722 0.656513496236914 0.757044040945461 PPP1R10/BMP7 2 GO:0043470 regulation of carbohydrate catabolic process 2/742 56/18722 0.656513496236914 0.757044040945461 APP/NCOR1 2 GO:0045071 negative regulation of viral genome replication 2/742 56/18722 0.656513496236914 0.757044040945461 MPHOSPH8/BANF1 2 GO:0046622 positive regulation of organ growth 2/742 56/18722 0.656513496236914 0.757044040945461 TGFBR3/IGF2 2 GO:0044106 cellular amine metabolic process 4/742 113/18722 0.659897046030554 0.760590622349728 ATP2B4/GATA3/EPAS1/CLN3 4 GO:0044344 cellular response to fibroblast growth factor stimulus 4/742 113/18722 0.659897046030554 0.760590622349728 ZFP36L1/GPC1/KDM5B/GATA3 4 GO:0002709 regulation of T cell mediated immunity 3/742 85/18722 0.660205286690885 0.760590978603771 CD81/CD55/GATA3 3 GO:0010507 negative regulation of autophagy 3/742 85/18722 0.660205286690885 0.760590978603771 MET/CTSA/EIF4G1 3 GO:0009117 nucleotide metabolic process 18/742 489/18722 0.660391348651637 0.760627946453506 GAPDH/SLC26A2/APP/LDHA/ALDOA/ACSS1/TPST2/TMSB4X/TPI1/CROT/ENO1/DLG1/NCOR1/NME3/PKM/PARP1/RAN/RHOA 18 GO:0030183 B cell differentiation 5/742 141/18722 0.66185178379367 0.761117520527873 ITGB1/PRKDC/ZFP36L1/YY1/TPD52 5 GO:1903038 negative regulation of leukocyte cell-cell adhesion 5/742 141/18722 0.66185178379367 0.761117520527873 DLG5/MIA3/ANXA1/GLI3/DLG1 5 GO:0022408 negative regulation of cell-cell adhesion 7/742 196/18722 0.663293908027099 0.761117520527873 CDH1/SPINT2/DLG5/MIA3/ANXA1/GLI3/DLG1 7 GO:0000469 cleavage involved in rRNA processing 1/742 27/18722 0.664668215294988 0.761117520527873 RPS21 1 GO:0002825 regulation of T-helper 1 type immune response 1/742 27/18722 0.664668215294988 0.761117520527873 ANXA1 1 GO:0003272 endocardial cushion formation 1/742 27/18722 0.664668215294988 0.761117520527873 BMP7 1 GO:0010758 regulation of macrophage chemotaxis 1/742 27/18722 0.664668215294988 0.761117520527873 MIF 1 GO:0010894 negative regulation of steroid biosynthetic process 1/742 27/18722 0.664668215294988 0.761117520527873 ATP1A1 1 GO:0016556 mRNA modification 1/742 27/18722 0.664668215294988 0.761117520527873 ZC3H13 1 GO:0018904 ether metabolic process 1/742 27/18722 0.664668215294988 0.761117520527873 TXN 1 GO:0032703 negative regulation of interleukin-2 production 1/742 27/18722 0.664668215294988 0.761117520527873 GATA3 1 GO:0032786 positive regulation of DNA-templated transcription, elongation 1/742 27/18722 0.664668215294988 0.761117520527873 BRD4 1 GO:0032967 positive regulation of collagen biosynthetic process 1/742 27/18722 0.664668215294988 0.761117520527873 SUCO 1 GO:0035459 vesicle cargo loading 1/742 27/18722 0.664668215294988 0.761117520527873 MIA3 1 GO:0039529 RIG-I signaling pathway 1/742 27/18722 0.664668215294988 0.761117520527873 PUM1 1 GO:0042104 positive regulation of activated T cell proliferation 1/742 27/18722 0.664668215294988 0.761117520527873 IGF2 1 GO:0042745 circadian sleep/wake cycle 1/742 27/18722 0.664668215294988 0.761117520527873 ADRB1 1 GO:0045606 positive regulation of epidermal cell differentiation 1/742 27/18722 0.664668215294988 0.761117520527873 NCOA3 1 GO:0046174 polyol catabolic process 1/742 27/18722 0.664668215294988 0.761117520527873 TPI1 1 GO:0046337 phosphatidylethanolamine metabolic process 1/742 27/18722 0.664668215294988 0.761117520527873 PISD 1 GO:0048520 positive regulation of behavior 1/742 27/18722 0.664668215294988 0.761117520527873 GJA1 1 GO:0060512 prostate gland morphogenesis 1/742 27/18722 0.664668215294988 0.761117520527873 BMP7 1 GO:1900746 regulation of vascular endothelial growth factor signaling pathway 1/742 27/18722 0.664668215294988 0.761117520527873 SEMA6A 1 GO:1901018 positive regulation of potassium ion transmembrane transporter activity 1/742 27/18722 0.664668215294988 0.761117520527873 AKAP9 1 GO:1903203 regulation of oxidative stress-induced neuron death 1/742 27/18722 0.664668215294988 0.761117520527873 PARP1 1 GO:0050879 multicellular organismal movement 2/742 57/18722 0.666039691989171 0.762334587216521 GAA/GSTO1 2 GO:0050881 musculoskeletal movement 2/742 57/18722 0.666039691989171 0.762334587216521 GAA/GSTO1 2 GO:0022406 membrane docking 3/742 86/18722 0.667967127074471 0.764363587618227 ROCK1/CALM1/CLN3 3 GO:0031023 microtubule organizing center organization 5/742 143/18722 0.673930650899012 0.769756059285319 GCC2/NPM1/PCM1/SLC16A1/RANBP1 5 GO:0070555 response to interleukin-1 5/742 143/18722 0.673930650899012 0.769756059285319 APP/EGR1/ANXA1/USP10/YY1 5 GO:0007405 neuroblast proliferation 2/742 58/18722 0.675351574767264 0.769756059285319 GLI3/NF1 2 GO:0010574 regulation of vascular endothelial growth factor production 2/742 58/18722 0.675351574767264 0.769756059285319 IL6ST/ISL1 2 GO:0032481 positive regulation of type I interferon production 2/742 58/18722 0.675351574767264 0.769756059285319 GAPDH/DHX36 2 GO:0097035 regulation of membrane lipid distribution 2/742 58/18722 0.675351574767264 0.769756059285319 KCNN4/ATP10D 2 GO:0016101 diterpenoid metabolic process 3/742 87/18722 0.675598653441559 0.769756059285319 LRP2/EGFR/LRP1 3 GO:0051048 negative regulation of secretion 6/742 171/18722 0.675918249385584 0.769756059285319 ERP29/GJA1/FRMD4A/ANXA1/PPP1R9A/ERBB3 6 GO:0008654 phospholipid biosynthetic process 9/742 253/18722 0.67635708529749 0.769756059285319 SERINC1/PISD/GPAA1/SLC44A2/PGAP1/ISYNA1/CDS1/CLN3/HEXB 9 GO:0000470 maturation of LSU-rRNA 1/742 28/18722 0.677977452216685 0.769756059285319 RPL7 1 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1/742 28/18722 0.677977452216685 0.769756059285319 CALR 1 GO:0002675 positive regulation of acute inflammatory response 1/742 28/18722 0.677977452216685 0.769756059285319 IL6ST 1 GO:0006515 protein quality control for misfolded or incompletely synthesized proteins 1/742 28/18722 0.677977452216685 0.769756059285319 YME1L1 1 GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway 1/742 28/18722 0.677977452216685 0.769756059285319 LRP1 1 GO:0009065 glutamine family amino acid catabolic process 1/742 28/18722 0.677977452216685 0.769756059285319 ATP2B4 1 GO:0009312 oligosaccharide biosynthetic process 1/742 28/18722 0.677977452216685 0.769756059285319 FUT8 1 GO:0010464 regulation of mesenchymal cell proliferation 1/742 28/18722 0.677977452216685 0.769756059285319 LRP5 1 GO:0010714 positive regulation of collagen metabolic process 1/742 28/18722 0.677977452216685 0.769756059285319 SUCO 1 GO:0010818 T cell chemotaxis 1/742 28/18722 0.677977452216685 0.769756059285319 PLEC 1 GO:0010884 positive regulation of lipid storage 1/742 28/18722 0.677977452216685 0.769756059285319 PLIN2 1 GO:0015740 C4-dicarboxylate transport 1/742 28/18722 0.677977452216685 0.769756059285319 SLC1A5 1 GO:0031342 negative regulation of cell killing 1/742 28/18722 0.677977452216685 0.769756059285319 SERPINB9 1 GO:0032607 interferon-alpha production 1/742 28/18722 0.677977452216685 0.769756059285319 DHX36 1 GO:0032647 regulation of interferon-alpha production 1/742 28/18722 0.677977452216685 0.769756059285319 DHX36 1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 1/742 28/18722 0.677977452216685 0.769756059285319 EGFR 1 GO:0044331 cell-cell adhesion mediated by cadherin 1/742 28/18722 0.677977452216685 0.769756059285319 CTNND1 1 GO:0045589 regulation of regulatory T cell differentiation 1/742 28/18722 0.677977452216685 0.769756059285319 CD46 1 GO:0045671 negative regulation of osteoclast differentiation 1/742 28/18722 0.677977452216685 0.769756059285319 FBN1 1 GO:0060259 regulation of feeding behavior 1/742 28/18722 0.677977452216685 0.769756059285319 EIF2AK4 1 GO:0061082 myeloid leukocyte cytokine production 1/742 28/18722 0.677977452216685 0.769756059285319 DHX36 1 GO:0071280 cellular response to copper ion 1/742 28/18722 0.677977452216685 0.769756059285319 APP 1 GO:0090200 positive regulation of release of cytochrome c from mitochondria 1/742 28/18722 0.677977452216685 0.769756059285319 PMAIP1 1 GO:1903671 negative regulation of sprouting angiogenesis 1/742 28/18722 0.677977452216685 0.769756059285319 SEMA6A 1 GO:1903672 positive regulation of sprouting angiogenesis 1/742 28/18722 0.677977452216685 0.769756059285319 PKM 1 GO:0031644 regulation of nervous system process 5/742 144/18722 0.679861906882905 0.771718249081238 AKAP9/APP/DAG1/CTSC/SLC9A1 5 GO:0030101 natural killer cell activation 3/742 88/18722 0.683099984106684 0.775215695264649 PBX1/HECTD1/LAMP1 3 GO:0072522 purine-containing compound biosynthetic process 7/742 200/18722 0.683701275642822 0.7756798928214 SLC26A2/ALDOA/ACSS1/TMSB4X/ENO1/NME3/PARP1 7 GO:0002820 negative regulation of adaptive immune response 2/742 59/18722 0.684451144293215 0.7756798928214 CD46/CD55 2 GO:0033013 tetrapyrrole metabolic process 2/742 59/18722 0.684451144293215 0.7756798928214 MTR/BLVRA 2 GO:0043551 regulation of phosphatidylinositol 3-kinase activity 2/742 59/18722 0.684451144293215 0.7756798928214 FLT1/CDC42 2 GO:0051353 positive regulation of oxidoreductase activity 2/742 59/18722 0.684451144293215 0.7756798928214 POR/CALM1 2 GO:2000351 regulation of endothelial cell apoptotic process 2/742 59/18722 0.684451144293215 0.7756798928214 GATA3/PDCD4 2 GO:0002237 response to molecule of bacterial origin 13/742 363/18722 0.685159126558721 0.77630414798167 JUN/FOS/JUND/GJA1/PABPN1/S100A9/CD55/ADM/FOXP1/NFKBIA/RHOA/HPGD/PDCD4 13 GO:0014902 myotube differentiation 4/742 117/18722 0.686437751794115 0.777396261775087 PLEC/CD81/PLD3/GPX1 4 GO:0030301 cholesterol transport 4/742 117/18722 0.686437751794115 0.777396261775087 LRP1/CAV1/SYT7/NFKBIA 4 GO:0006753 nucleoside phosphate metabolic process 18/742 497/18722 0.686700905889536 0.777516038298031 GAPDH/SLC26A2/APP/LDHA/ALDOA/ACSS1/TPST2/TMSB4X/TPI1/CROT/ENO1/DLG1/NCOR1/NME3/PKM/PARP1/RAN/RHOA 18 GO:0010657 muscle cell apoptotic process 3/742 89/18722 0.690471352946222 0.778187027217533 PPP1R10/BMP7/PDCD4 3 GO:0001773 myeloid dendritic cell activation 1/742 29/18722 0.690759132459288 0.778187027217533 DHRS2 1 GO:0002068 glandular epithelial cell development 1/742 29/18722 0.690759132459288 0.778187027217533 CDK6 1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus 1/742 29/18722 0.690759132459288 0.778187027217533 GPX1 1 GO:0003309 type B pancreatic cell differentiation 1/742 29/18722 0.690759132459288 0.778187027217533 CDK6 1 GO:0005979 regulation of glycogen biosynthetic process 1/742 29/18722 0.690759132459288 0.778187027217533 IGF2 1 GO:0006734 NADH metabolic process 1/742 29/18722 0.690759132459288 0.778187027217533 ENO1 1 GO:0009218 pyrimidine ribonucleotide metabolic process 1/742 29/18722 0.690759132459288 0.778187027217533 NME3 1 GO:0009310 amine catabolic process 1/742 29/18722 0.690759132459288 0.778187027217533 ATP2B4 1 GO:0010962 regulation of glucan biosynthetic process 1/742 29/18722 0.690759132459288 0.778187027217533 IGF2 1 GO:0015701 bicarbonate transport 1/742 29/18722 0.690759132459288 0.778187027217533 SLC26A2 1 GO:0032366 intracellular sterol transport 1/742 29/18722 0.690759132459288 0.778187027217533 SYT7 1 GO:0032367 intracellular cholesterol transport 1/742 29/18722 0.690759132459288 0.778187027217533 SYT7 1 GO:0042759 long-chain fatty acid biosynthetic process 1/742 29/18722 0.690759132459288 0.778187027217533 GPX4 1 GO:0043153 entrainment of circadian clock by photoperiod 1/742 29/18722 0.690759132459288 0.778187027217533 NR2F6 1 GO:0048265 response to pain 1/742 29/18722 0.690759132459288 0.778187027217533 VWA1 1 GO:0051654 establishment of mitochondrion localization 1/742 29/18722 0.690759132459288 0.778187027217533 ARMCX3 1 GO:0051873 killing by host of symbiont cells 1/742 29/18722 0.690759132459288 0.778187027217533 GAPDH 1 GO:0051883 killing of cells in other organism involved in symbiotic interaction 1/742 29/18722 0.690759132459288 0.778187027217533 GAPDH 1 GO:0090114 COPII-coated vesicle budding 1/742 29/18722 0.690759132459288 0.778187027217533 MIA3 1 GO:0095500 acetylcholine receptor signaling pathway 1/742 29/18722 0.690759132459288 0.778187027217533 GNAQ 1 GO:0098868 bone growth 1/742 29/18722 0.690759132459288 0.778187027217533 POR 1 GO:0007613 memory 4/742 118/18722 0.692839629432108 0.779672765133208 SERPINF1/SLC6A4/LGMN/EIF2AK4 4 GO:0009308 amine metabolic process 4/742 118/18722 0.692839629432108 0.779672765133208 ATP2B4/GATA3/EPAS1/CLN3 4 GO:0031663 lipopolysaccharide-mediated signaling pathway 2/742 60/18722 0.693340578386676 0.779672765133208 CD55/NFKBIA 2 GO:0033866 nucleoside bisphosphate biosynthetic process 2/742 60/18722 0.693340578386676 0.779672765133208 SLC26A2/ACSS1 2 GO:0034030 ribonucleoside bisphosphate biosynthetic process 2/742 60/18722 0.693340578386676 0.779672765133208 SLC26A2/ACSS1 2 GO:0034033 purine nucleoside bisphosphate biosynthetic process 2/742 60/18722 0.693340578386676 0.779672765133208 SLC26A2/ACSS1 2 GO:0051965 positive regulation of synapse assembly 2/742 60/18722 0.693340578386676 0.779672765133208 DLG5/TPBG 2 GO:1903670 regulation of sprouting angiogenesis 2/742 60/18722 0.693340578386676 0.779672765133208 SEMA6A/PKM 2 GO:0017157 regulation of exocytosis 7/742 202/18722 0.69360513430048 0.779792754539001 ATP6AP1/ANXA1/SYT7/VAMP2/LAMP1/CALM1/SDCBP 7 GO:0045333 cellular respiration 8/742 230/18722 0.695828516786704 0.782114419323394 COX6A1/PLEC/IL10RB/NDUFB9/UQCRH/COX8C/RHOA/COX5A 8 GO:1903531 negative regulation of secretion by cell 5/742 147/18722 0.697219333055076 0.783341529544527 ERP29/GJA1/FRMD4A/ANXA1/PPP1R9A 5 GO:0035278 miRNA mediated inhibition of translation 3/742 90/18722 0.69771310323804 0.783341529544527 TNRC6A/EIF4G1/TNRC6B 3 GO:0040033 negative regulation of translation, ncRNA-mediated 3/742 90/18722 0.69771310323804 0.783341529544527 TNRC6A/EIF4G1/TNRC6B 3 GO:0048477 oogenesis 3/742 90/18722 0.69771310323804 0.783341529544527 RPS6/LGR5/HEXB 3 GO:0061097 regulation of protein tyrosine kinase activity 3/742 90/18722 0.69771310323804 0.783341529544527 APP/CAV1/ERBB3 3 GO:0031348 negative regulation of defense response 9/742 258/18722 0.698455353664235 0.783996693274556 GRN/SERPINF1/ISL1/ASH1L/PCBP2/GATA3/ADAR/GPX1/SERPINB9 9 GO:0050728 negative regulation of inflammatory response 6/742 176/18722 0.702464452343984 0.785388659803224 GRN/SERPINF1/ISL1/ASH1L/GATA3/GPX1 6 GO:0044272 sulfur compound biosynthetic process 5/742 148/18722 0.702858967656952 0.785388659803224 SLC26A2/CHPF/ACSS1/B4GAT1/MTR 5 GO:0003299 muscle hypertrophy in response to stress 1/742 30/18722 0.703034140414951 0.785388659803224 ATP2B4 1 GO:0006221 pyrimidine nucleotide biosynthetic process 1/742 30/18722 0.703034140414951 0.785388659803224 NME3 1 GO:0007176 regulation of epidermal growth factor-activated receptor activity 1/742 30/18722 0.703034140414951 0.785388659803224 APP 1 GO:0014887 cardiac muscle adaptation 1/742 30/18722 0.703034140414951 0.785388659803224 ATP2B4 1 GO:0014898 cardiac muscle hypertrophy in response to stress 1/742 30/18722 0.703034140414951 0.785388659803224 ATP2B4 1 GO:0030204 chondroitin sulfate metabolic process 1/742 30/18722 0.703034140414951 0.785388659803224 CHPF 1 GO:0032480 negative regulation of type I interferon production 1/742 30/18722 0.703034140414951 0.785388659803224 YY1 1 GO:0033137 negative regulation of peptidyl-serine phosphorylation 1/742 30/18722 0.703034140414951 0.785388659803224 CAV1 1 GO:0034390 smooth muscle cell apoptotic process 1/742 30/18722 0.703034140414951 0.785388659803224 PDCD4 1 GO:0034391 regulation of smooth muscle cell apoptotic process 1/742 30/18722 0.703034140414951 0.785388659803224 PDCD4 1 GO:0036258 multivesicular body assembly 1/742 30/18722 0.703034140414951 0.785388659803224 RAB11A 1 GO:0045577 regulation of B cell differentiation 1/742 30/18722 0.703034140414951 0.785388659803224 ZFP36L1 1 GO:0045939 negative regulation of steroid metabolic process 1/742 30/18722 0.703034140414951 0.785388659803224 ATP1A1 1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway 1/742 30/18722 0.703034140414951 0.785388659803224 PHPT1 1 GO:0051125 regulation of actin nucleation 1/742 30/18722 0.703034140414951 0.785388659803224 WASF2 1 GO:0051968 positive regulation of synaptic transmission, glutamatergic 1/742 30/18722 0.703034140414951 0.785388659803224 EGFR 1 GO:0060292 long-term synaptic depression 1/742 30/18722 0.703034140414951 0.785388659803224 PPP1R9A 1 GO:0061311 cell surface receptor signaling pathway involved in heart development 1/742 30/18722 0.703034140414951 0.785388659803224 GALNT11 1 GO:0070498 interleukin-1-mediated signaling pathway 1/742 30/18722 0.703034140414951 0.785388659803224 EGR1 1 GO:0002275 myeloid cell activation involved in immune response 3/742 91/18722 0.704825681681673 0.787034102058649 GRN/VAMP2/ANXA3 3 GO:0045974 regulation of translation, ncRNA-mediated 3/742 91/18722 0.704825681681673 0.787034102058649 TNRC6A/EIF4G1/TNRC6B 3 GO:0071466 cellular response to xenobiotic stimulus 6/742 177/18722 0.707593832168136 0.789946560657761 EGFR/HSPA5/TFRC/GSTO1/POR/CYP2J2 6 GO:0002260 lymphocyte homeostasis 2/742 62/18722 0.710498539820913 0.79229408277998 RPS6/PMAIP1 2 GO:0007062 sister chromatid cohesion 2/742 62/18722 0.710498539820913 0.79229408277998 ATRX/NIPBL 2 GO:0032615 interleukin-12 production 2/742 62/18722 0.710498539820913 0.79229408277998 ISL1/FOXP1 2 GO:0032655 regulation of interleukin-12 production 2/742 62/18722 0.710498539820913 0.79229408277998 ISL1/FOXP1 2 GO:0046173 polyol biosynthetic process 2/742 62/18722 0.710498539820913 0.79229408277998 ISYNA1/ASAH1 2 GO:0006497 protein lipidation 3/742 92/18722 0.711809632599363 0.79264272096593 GPAA1/PGAP1/NMT1 3 GO:0034502 protein localization to chromosome 3/742 92/18722 0.711809632599363 0.79264272096593 ATRX/NIPBL/CCT3 3 GO:0048525 negative regulation of viral process 3/742 92/18722 0.711809632599363 0.79264272096593 MPHOSPH8/PPIA/BANF1 3 GO:1903351 cellular response to dopamine 3/742 92/18722 0.711809632599363 0.79264272096593 NCSTN/ID1/TGM2 3 GO:0002063 chondrocyte development 1/742 31/18722 0.714822534798222 0.79264272096593 SERPINH1 1 GO:0002323 natural killer cell activation involved in immune response 1/742 31/18722 0.714822534798222 0.79264272096593 LAMP1 1 GO:0006301 postreplication repair 1/742 31/18722 0.714822534798222 0.79264272096593 USP10 1 GO:0018200 peptidyl-glutamic acid modification 1/742 31/18722 0.714822534798222 0.79264272096593 PARP1 1 GO:0032509 endosome transport via multivesicular body sorting pathway 1/742 31/18722 0.714822534798222 0.79264272096593 LEPROT 1 GO:0035115 embryonic forelimb morphogenesis 1/742 31/18722 0.714822534798222 0.79264272096593 NIPBL 1 GO:0036257 multivesicular body organization 1/742 31/18722 0.714822534798222 0.79264272096593 RAB11A 1 GO:0045066 regulatory T cell differentiation 1/742 31/18722 0.714822534798222 0.79264272096593 CD46 1 GO:0045987 positive regulation of smooth muscle contraction 1/742 31/18722 0.714822534798222 0.79264272096593 RHOA 1 GO:0050482 arachidonic acid secretion 1/742 31/18722 0.714822534798222 0.79264272096593 ANXA1 1 GO:0060045 positive regulation of cardiac muscle cell proliferation 1/742 31/18722 0.714822534798222 0.79264272096593 TGFBR3 1 GO:0060795 cell fate commitment involved in formation of primary germ layer 1/742 31/18722 0.714822534798222 0.79264272096593 RTF1 1 GO:0061099 negative regulation of protein tyrosine kinase activity 1/742 31/18722 0.714822534798222 0.79264272096593 CAV1 1 GO:0070528 protein kinase C signaling 1/742 31/18722 0.714822534798222 0.79264272096593 ADGRG1 1 GO:0070633 transepithelial transport 1/742 31/18722 0.714822534798222 0.79264272096593 ACTG1 1 GO:0070723 response to cholesterol 1/742 31/18722 0.714822534798222 0.79264272096593 DAG1 1 GO:0071168 protein localization to chromatin 1/742 31/18722 0.714822534798222 0.79264272096593 NIPBL 1 GO:0097106 postsynaptic density organization 1/742 31/18722 0.714822534798222 0.79264272096593 DLG1 1 GO:1901797 negative regulation of signal transduction by p53 class mediator 1/742 31/18722 0.714822534798222 0.79264272096593 MIF 1 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 1/742 31/18722 0.714822534798222 0.79264272096593 GPX1 1 GO:1903963 arachidonate transport 1/742 31/18722 0.714822534798222 0.79264272096593 ANXA1 1 GO:0050868 negative regulation of T cell activation 4/742 122/18722 0.717511624819544 0.795446011357394 DLG5/ANXA1/GLI3/DLG1 4 GO:1903350 response to dopamine 3/742 93/18722 0.718665592317793 0.795950344899993 NCSTN/ID1/TGM2 3 GO:0001947 heart looping 2/742 63/18722 0.718772163683982 0.795950344899993 FOLR1/CITED2 2 GO:0016239 positive regulation of macroautophagy 2/742 63/18722 0.718772163683982 0.795950344899993 LARP1/VDAC1 2 GO:0031343 positive regulation of cell killing 2/742 63/18722 0.718772163683982 0.795950344899993 CADM1/LAMP1 2 GO:0099601 regulation of neurotransmitter receptor activity 2/742 63/18722 0.718772163683982 0.795950344899993 AKAP9/APP 2 GO:0006261 DNA-dependent DNA replication 5/742 151/18722 0.719337571860286 0.796219494732201 BOD1L1/ATRX/PURA/HMGA1/CCNE1 5 GO:0031497 chromatin assembly 5/742 151/18722 0.719337571860286 0.796219494732201 ATRX/NPM1/BRD2/HP1BP3/RSF1 5 GO:0050852 T cell receptor signaling pathway 4/742 123/18722 0.723446170461804 0.800587832007462 KCNN4/CD81/GATA3/PHPT1 4 GO:0050871 positive regulation of B cell activation 5/742 152/18722 0.724683537447486 0.801239511137294 SLC39A10/TFRC/MIF/CD81/RIF1 5 GO:0010667 negative regulation of cardiac muscle cell apoptotic process 1/742 32/18722 0.7261435812473 0.801239511137294 PPP1R10 1 GO:0019228 neuronal action potential 1/742 32/18722 0.7261435812473 0.801239511137294 ANK3 1 GO:0032196 transposition 1/742 32/18722 0.7261435812473 0.801239511137294 L1TD1 1 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter 1/742 32/18722 0.7261435812473 0.801239511137294 BRD4 1 GO:0042219 cellular modified amino acid catabolic process 1/742 32/18722 0.7261435812473 0.801239511137294 PCYOX1 1 GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 1/742 32/18722 0.7261435812473 0.801239511137294 ANXA1 1 GO:0045684 positive regulation of epidermis development 1/742 32/18722 0.7261435812473 0.801239511137294 NCOA3 1 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity 1/742 32/18722 0.7261435812473 0.801239511137294 NR2F2 1 GO:0045879 negative regulation of smoothened signaling pathway 1/742 32/18722 0.7261435812473 0.801239511137294 GLI3 1 GO:0046475 glycerophospholipid catabolic process 1/742 32/18722 0.7261435812473 0.801239511137294 PRDX6 1 GO:0050850 positive regulation of calcium-mediated signaling 1/742 32/18722 0.7261435812473 0.801239511137294 SLC9A1 1 GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 1/742 32/18722 0.7261435812473 0.801239511137294 ANXA1 1 GO:0030858 positive regulation of epithelial cell differentiation 2/742 64/18722 0.726845815902445 0.801310983575744 BTG1/NCOA3 2 GO:0046530 photoreceptor cell differentiation 2/742 64/18722 0.726845815902445 0.801310983575744 NAGLU/TUG1 2 GO:1903409 reactive oxygen species biosynthetic process 2/742 64/18722 0.726845815902445 0.801310983575744 SLC5A3/RHOA 2 GO:1901617 organic hydroxy compound biosynthetic process 8/742 237/18722 0.726857189757673 0.801310983575744 DHCR24/SLC27A2/POR/ISYNA1/MBTPS1/ASAH1/GATA3/HSD17B1 8 GO:0007368 determination of left/right symmetry 4/742 124/18722 0.729287712625862 0.803811088882588 GALNT11/FOLR1/TMEM107/CITED2 4 GO:0032479 regulation of type I interferon production 3/742 95/18722 0.73199651103558 0.806257026647885 GAPDH/DHX36/YY1 3 GO:0032606 type I interferon production 3/742 95/18722 0.73199651103558 0.806257026647885 GAPDH/DHX36/YY1 3 GO:0045666 positive regulation of neuron differentiation 3/742 95/18722 0.73199651103558 0.806257026647885 BMP7/EIF4G1/RHOA 3 GO:0072577 endothelial cell apoptotic process 2/742 65/18722 0.734722327300447 0.808899793641472 GATA3/PDCD4 2 GO:0002449 lymphocyte mediated immunity 12/742 350/18722 0.736346692278762 0.808899793641472 CD46/CTSC/CADM1/TFRC/CD81/KIF5B/CD55/LAMP1/RIF1/GATA3/SERPINB9/TUBB4B 12 GO:0006336 DNA replication-independent nucleosome assembly 1/742 33/18722 0.73701578363973 0.808899793641472 ATRX 1 GO:0006891 intra-Golgi vesicle-mediated transport 1/742 33/18722 0.73701578363973 0.808899793641472 CUX1 1 GO:0009648 photoperiodism 1/742 33/18722 0.73701578363973 0.808899793641472 NR2F6 1 GO:0010737 protein kinase A signaling 1/742 33/18722 0.73701578363973 0.808899793641472 MIF 1 GO:0033198 response to ATP 1/742 33/18722 0.73701578363973 0.808899793641472 HSP90B1 1 GO:0040020 regulation of meiotic nuclear division 1/742 33/18722 0.73701578363973 0.808899793641472 CALR 1 GO:0045920 negative regulation of exocytosis 1/742 33/18722 0.73701578363973 0.808899793641472 ANXA1 1 GO:0046320 regulation of fatty acid oxidation 1/742 33/18722 0.73701578363973 0.808899793641472 ACADVL 1 GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 1/742 33/18722 0.73701578363973 0.808899793641472 DHX36 1 GO:0071763 nuclear membrane organization 1/742 33/18722 0.73701578363973 0.808899793641472 NEK6 1 GO:0099084 postsynaptic specialization organization 1/742 33/18722 0.73701578363973 0.808899793641472 DLG1 1 GO:0110110 positive regulation of animal organ morphogenesis 1/742 33/18722 0.73701578363973 0.808899793641472 GATA3 1 GO:1903715 regulation of aerobic respiration 1/742 33/18722 0.73701578363973 0.808899793641472 RHOA 1 GO:1904030 negative regulation of cyclin-dependent protein kinase activity 1/742 33/18722 0.73701578363973 0.808899793641472 NR2F2 1 GO:0042158 lipoprotein biosynthetic process 3/742 96/18722 0.73847315466032 0.810139325787693 GPAA1/PGAP1/NMT1 3 GO:0042472 inner ear morphogenesis 3/742 96/18722 0.73847315466032 0.810139325787693 TRIOBP/ATP6V1B1/GATA3 3 GO:0030258 lipid modification 7/742 212/18722 0.740056263457238 0.811695812939333 SLC27A2/PLPP3/POR/CROT/ACADVL/HADHA/ETFA 7 GO:0051147 regulation of muscle cell differentiation 5/742 155/18722 0.74028127826347 0.811762378384359 YBX1/YY1/IGF2/MORF4L2/PDCD4 5 GO:0006303 double-strand break repair via nonhomologous end joining 2/742 66/18722 0.742404618595831 0.813368555303483 PRKDC/RIF1 2 GO:0046626 regulation of insulin receptor signaling pathway 2/742 66/18722 0.742404618595831 0.813368555303483 KANK1/IGF2 2 GO:0071300 cellular response to retinoic acid 2/742 66/18722 0.742404618595831 0.813368555303483 SERPINF1/SLC6A4 2 GO:1905953 negative regulation of lipid localization 2/742 66/18722 0.742404618595831 0.813368555303483 ITGAV/NFKBIA 2 GO:0006721 terpenoid metabolic process 3/742 97/18722 0.744825166349259 0.815107539959254 LRP2/EGFR/LRP1 3 GO:1990868 response to chemokine 3/742 97/18722 0.744825166349259 0.815107539959254 DUSP1/DOCK8/RHOA 3 GO:1990869 cellular response to chemokine 3/742 97/18722 0.744825166349259 0.815107539959254 DUSP1/DOCK8/RHOA 3 GO:0000096 sulfur amino acid metabolic process 1/742 34/18722 0.747456914173162 0.815107539959254 MTR 1 GO:0002446 neutrophil mediated immunity 1/742 34/18722 0.747456914173162 0.815107539959254 ANXA3 1 GO:0007616 long-term memory 1/742 34/18722 0.747456914173162 0.815107539959254 EIF2AK4 1 GO:0010661 positive regulation of muscle cell apoptotic process 1/742 34/18722 0.747456914173162 0.815107539959254 PDCD4 1 GO:0014072 response to isoquinoline alkaloid 1/742 34/18722 0.747456914173162 0.815107539959254 FOSB 1 GO:0030851 granulocyte differentiation 1/742 34/18722 0.747456914173162 0.815107539959254 CITED2 1 GO:0034383 low-density lipoprotein particle clearance 1/742 34/18722 0.747456914173162 0.815107539959254 CNPY2 1 GO:0034724 DNA replication-independent nucleosome organization 1/742 34/18722 0.747456914173162 0.815107539959254 ATRX 1 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus 1/742 34/18722 0.747456914173162 0.815107539959254 PUM1 1 GO:0043278 response to morphine 1/742 34/18722 0.747456914173162 0.815107539959254 FOSB 1 GO:0050931 pigment cell differentiation 1/742 34/18722 0.747456914173162 0.815107539959254 GLI3 1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 1/742 34/18722 0.747456914173162 0.815107539959254 TGM2 1 GO:0051973 positive regulation of telomerase activity 1/742 34/18722 0.747456914173162 0.815107539959254 PTGES3 1 GO:0070050 neuron cellular homeostasis 1/742 34/18722 0.747456914173162 0.815107539959254 ATP2B1 1 GO:0070232 regulation of T cell apoptotic process 1/742 34/18722 0.747456914173162 0.815107539959254 DOCK8 1 GO:0090075 relaxation of muscle 1/742 34/18722 0.747456914173162 0.815107539959254 ATP1A1 1 GO:2000352 negative regulation of endothelial cell apoptotic process 1/742 34/18722 0.747456914173162 0.815107539959254 GATA3 1 GO:2000780 negative regulation of double-strand break repair 1/742 34/18722 0.747456914173162 0.815107539959254 RIF1 1 GO:0042130 negative regulation of T cell proliferation 2/742 67/18722 0.749895688852439 0.817406156869164 DLG5/DLG1 2 GO:0061371 determination of heart left/right asymmetry 2/742 67/18722 0.749895688852439 0.817406156869164 FOLR1/CITED2 2 GO:2000377 regulation of reactive oxygen species metabolic process 5/742 157/18722 0.750314211246318 0.817681933279685 EGFR/BMP7/SLC5A3/VDAC1/RHOA 5 GO:0033865 nucleoside bisphosphate metabolic process 4/742 128/18722 0.751730317668294 0.81868337065286 SLC26A2/ACSS1/TPST2/CROT 4 GO:0033875 ribonucleoside bisphosphate metabolic process 4/742 128/18722 0.751730317668294 0.81868337065286 SLC26A2/ACSS1/TPST2/CROT 4 GO:0034032 purine nucleoside bisphosphate metabolic process 4/742 128/18722 0.751730317668294 0.81868337065286 SLC26A2/ACSS1/TPST2/CROT 4 GO:0007631 feeding behavior 3/742 99/18722 0.757159429279068 0.821869354000335 FOS/APP/EIF2AK4 3 GO:0051153 regulation of striated muscle cell differentiation 3/742 99/18722 0.757159429279068 0.821869354000335 YBX1/YY1/MORF4L2 3 GO:0009247 glycolipid biosynthetic process 2/742 68/18722 0.757198604704359 0.821869354000335 GPAA1/PGAP1 2 GO:0031640 killing of cells of other organism 2/742 68/18722 0.757198604704359 0.821869354000335 GAPDH/SERPINB9 2 GO:0000731 DNA synthesis involved in DNA repair 1/742 35/18722 0.757484042259823 0.821869354000335 USP10 1 GO:0001569 branching involved in blood vessel morphogenesis 1/742 35/18722 0.757484042259823 0.821869354000335 NRP1 1 GO:0006084 acetyl-CoA metabolic process 1/742 35/18722 0.757484042259823 0.821869354000335 ACSS1 1 GO:0006471 protein ADP-ribosylation 1/742 35/18722 0.757484042259823 0.821869354000335 PARP1 1 GO:0006691 leukotriene metabolic process 1/742 35/18722 0.757484042259823 0.821869354000335 MGST3 1 GO:0008608 attachment of spindle microtubules to kinetochore 1/742 35/18722 0.757484042259823 0.821869354000335 CDC42 1 GO:0021955 central nervous system neuron axonogenesis 1/742 35/18722 0.757484042259823 0.821869354000335 MYCBP2 1 GO:0032814 regulation of natural killer cell activation 1/742 35/18722 0.757484042259823 0.821869354000335 LAMP1 1 GO:0046471 phosphatidylglycerol metabolic process 1/742 35/18722 0.757484042259823 0.821869354000335 HADHA 1 GO:0046627 negative regulation of insulin receptor signaling pathway 1/742 35/18722 0.757484042259823 0.821869354000335 KANK1 1 GO:0070536 protein K63-linked deubiquitination 1/742 35/18722 0.757484042259823 0.821869354000335 USP27X 1 GO:0072528 pyrimidine-containing compound biosynthetic process 1/742 35/18722 0.757484042259823 0.821869354000335 NME3 1 GO:0097502 mannosylation 1/742 35/18722 0.757484042259823 0.821869354000335 B4GAT1 1 GO:0022412 cellular process involved in reproduction in multicellular organism 13/742 384/18722 0.757924787172163 0.822166984767344 ITGB1/RPS6/LGR5/SPESP1/DYNLL1/JAM3/FOLR1/AFF4/CELF1/SMARCA2/HEXB/PRDX4/EIF2S2 13 GO:0002443 leukocyte mediated immunity 15/742 440/18722 0.760978782094916 0.825298613292839 CD46/CTSC/CADM1/TFRC/CD81/KIF5B/CD55/VAMP2/LAMP1/DHX36/RIF1/GATA3/SERPINB9/ANXA3/TUBB4B 15 GO:0070374 positive regulation of ERK1 and ERK2 cascade 7/742 217/18722 0.761344217168933 0.825513703427246 EGFR/LRP1/APP/MIF/ATP6AP1/NRP1/TPBG 7 GO:0006352 DNA-templated transcription, initiation 4/742 130/18722 0.762403360452809 0.825936973823877 JUN/BDP1/DHX36/RSF1 4 GO:0007098 centrosome cycle 4/742 130/18722 0.762403360452809 0.825936973823877 NPM1/PCM1/SLC16A1/RANBP1 4 GO:0015918 sterol transport 4/742 130/18722 0.762403360452809 0.825936973823877 LRP1/CAV1/SYT7/NFKBIA 4 GO:0030534 adult behavior 4/742 130/18722 0.762403360452809 0.825936973823877 APP/NCSTN/PUM1/ATP6V1B1 4 GO:0045807 positive regulation of endocytosis 3/742 100/18722 0.763143898876626 0.826376777827824 LRP1/CLN3/CDC42 3 GO:0051588 regulation of neurotransmitter transport 3/742 100/18722 0.763143898876626 0.826376777827824 ITGB1/PPP1R9A/CALM1 3 GO:0071216 cellular response to biotic stimulus 8/742 246/18722 0.763510019320237 0.826592043708519 HSPA5/CCDC47/PABPN1/CD55/DDIT3/NFKBIA/RHOA/PDCD4 8 GO:0050805 negative regulation of synaptic transmission 2/742 69/18722 0.76431649030918 0.82703750157823 SLC6A4/PPP1R9A 2 GO:0051966 regulation of synaptic transmission, glutamatergic 2/742 69/18722 0.76431649030918 0.82703750157823 EGFR/CLN3 2 GO:0009060 aerobic respiration 6/742 189/18722 0.76442373121583 0.82703750157823 COX6A1/NDUFB9/UQCRH/COX8C/RHOA/COX5A 6 GO:0002691 regulation of cellular extravasation 1/742 36/18722 0.7671135622814 0.827230080259793 JAM3 1 GO:0006699 bile acid biosynthetic process 1/742 36/18722 0.7671135622814 0.827230080259793 SLC27A2 1 GO:0014046 dopamine secretion 1/742 36/18722 0.7671135622814 0.827230080259793 SYT7 1 GO:0014059 regulation of dopamine secretion 1/742 36/18722 0.7671135622814 0.827230080259793 SYT7 1 GO:0017004 cytochrome complex assembly 1/742 36/18722 0.7671135622814 0.827230080259793 COX20 1 GO:0036314 response to sterol 1/742 36/18722 0.7671135622814 0.827230080259793 DAG1 1 GO:0038179 neurotrophin signaling pathway 1/742 36/18722 0.7671135622814 0.827230080259793 KIDINS220 1 GO:0044060 regulation of endocrine process 1/742 36/18722 0.7671135622814 0.827230080259793 GJA1 1 GO:0045738 negative regulation of DNA repair 1/742 36/18722 0.7671135622814 0.827230080259793 RIF1 1 GO:0060338 regulation of type I interferon-mediated signaling pathway 1/742 36/18722 0.7671135622814 0.827230080259793 ADAR 1 GO:0070306 lens fiber cell differentiation 1/742 36/18722 0.7671135622814 0.827230080259793 KDM5B 1 GO:0070873 regulation of glycogen metabolic process 1/742 36/18722 0.7671135622814 0.827230080259793 IGF2 1 GO:0070897 transcription preinitiation complex assembly 1/742 36/18722 0.7671135622814 0.827230080259793 BDP1 1 GO:0086010 membrane depolarization during action potential 1/742 36/18722 0.7671135622814 0.827230080259793 ANK3 1 GO:0097009 energy homeostasis 1/742 36/18722 0.7671135622814 0.827230080259793 EIF4G1 1 GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response 2/742 70/18722 0.771252517989559 0.831511881027591 TFRC/RIF1 2 GO:0006650 glycerophospholipid metabolic process 10/742 306/18722 0.776089875320171 0.834470067021602 SERINC1/PISD/GPAA1/SLC44A2/PGAP1/CDS1/SERINC3/HADHA/PRDX6/CLN3 10 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 1/742 37/18722 0.776361220249247 0.834470067021602 UPF2 1 GO:0003016 respiratory system process 1/742 37/18722 0.776361220249247 0.834470067021602 GAA 1 GO:0007340 acrosome reaction 1/742 37/18722 0.776361220249247 0.834470067021602 SPESP1 1 GO:0016202 regulation of striated muscle tissue development 1/742 37/18722 0.776361220249247 0.834470067021602 IGF2 1 GO:0030513 positive regulation of BMP signaling pathway 1/742 37/18722 0.776361220249247 0.834470067021602 HES1 1 GO:0031646 positive regulation of nervous system process 1/742 37/18722 0.776361220249247 0.834470067021602 DAG1 1 GO:0033260 nuclear DNA replication 1/742 37/18722 0.776361220249247 0.834470067021602 ATRX 1 GO:0042401 cellular biogenic amine biosynthetic process 1/742 37/18722 0.776361220249247 0.834470067021602 GATA3 1 GO:0043368 positive T cell selection 1/742 37/18722 0.776361220249247 0.834470067021602 CTSL 1 GO:0051954 positive regulation of amine transport 1/742 37/18722 0.776361220249247 0.834470067021602 ITGB1 1 GO:0071985 multivesicular body sorting pathway 1/742 37/18722 0.776361220249247 0.834470067021602 LEPROT 1 GO:0072529 pyrimidine-containing compound catabolic process 1/742 37/18722 0.776361220249247 0.834470067021602 TET2 1 GO:1900077 negative regulation of cellular response to insulin stimulus 1/742 37/18722 0.776361220249247 0.834470067021602 KANK1 1 GO:0008344 adult locomotory behavior 2/742 71/18722 0.778009899524403 0.835878404447706 APP/PUM1 2 GO:0050818 regulation of coagulation 2/742 71/18722 0.778009899524403 0.835878404447706 CAV1/ANXA5 2 GO:0019233 sensory perception of pain 3/742 103/18722 0.780381093102788 0.838243661649874 MME/SLC9A1/NR2F6 3 GO:0032147 activation of protein kinase activity 4/742 134/18722 0.782674427902941 0.840524276921854 PRLR/DLG1/PPIA/TXN 4 GO:0009309 amine biosynthetic process 1/742 38/18722 0.785242139413018 0.842000470740245 GATA3 1 GO:0010719 negative regulation of epithelial to mesenchymal transition 1/742 38/18722 0.785242139413018 0.842000470740245 GATA3 1 GO:0030279 negative regulation of ossification 1/742 38/18722 0.785242139413018 0.842000470740245 LTBP3 1 GO:0048246 macrophage chemotaxis 1/742 38/18722 0.785242139413018 0.842000470740245 MIF 1 GO:0051930 regulation of sensory perception of pain 1/742 38/18722 0.785242139413018 0.842000470740245 SLC9A1 1 GO:0098926 postsynaptic signal transduction 1/742 38/18722 0.785242139413018 0.842000470740245 GNAQ 1 GO:1901186 positive regulation of ERBB signaling pathway 1/742 38/18722 0.785242139413018 0.842000470740245 RTN4 1 GO:0009581 detection of external stimulus 4/742 135/18722 0.787521972414827 0.844122528106532 NMT1/CDS1/GNAQ/NR2F6 4 GO:0007286 spermatid development 5/742 165/18722 0.787562901223281 0.844122528106532 DYNLL1/JAM3/AFF4/CELF1/SMARCA2 5 GO:0042058 regulation of epidermal growth factor receptor signaling pathway 2/742 73/18722 0.791001720557445 0.847440576784597 EGFR/PTPN12 2 GO:0051865 protein autoubiquitination 2/742 73/18722 0.791001720557445 0.847440576784597 HECTD1/RNF13 2 GO:0016079 synaptic vesicle exocytosis 3/742 105/18722 0.791288663769958 0.847564180187249 SYT7/VAMP2/CALM1 3 GO:0002701 negative regulation of production of molecular mediator of immune response 1/742 39/18722 0.793770844859151 0.848750643637274 PRKDC 1 GO:0016572 histone phosphorylation 1/742 39/18722 0.793770844859151 0.848750643637274 BAZ1B 1 GO:0017158 regulation of calcium ion-dependent exocytosis 1/742 39/18722 0.793770844859151 0.848750643637274 SYT7 1 GO:0021587 cerebellum morphogenesis 1/742 39/18722 0.793770844859151 0.848750643637274 HSPA5 1 GO:0045622 regulation of T-helper cell differentiation 1/742 39/18722 0.793770844859151 0.848750643637274 ANXA1 1 GO:0045923 positive regulation of fatty acid metabolic process 1/742 39/18722 0.793770844859151 0.848750643637274 ANXA1 1 GO:0051931 regulation of sensory perception 1/742 39/18722 0.793770844859151 0.848750643637274 SLC9A1 1 GO:1901861 regulation of muscle tissue development 1/742 39/18722 0.793770844859151 0.848750643637274 IGF2 1 GO:0019932 second-messenger-mediated signaling 10/742 312/18722 0.795699208015766 0.850628454360071 EGFR/GSTO1/ATP2B4/NFAT5/SLC9A1/PPP1R9A/ADM/CALM1/BCAP31/CALM2 10 GO:0060078 regulation of postsynaptic membrane potential 4/742 137/18722 0.796957793104836 0.851789592803524 APP/GABRE/ADRB1/PPP1R9A 4 GO:0046470 phosphatidylcholine metabolic process 2/742 74/18722 0.797242710889851 0.851891352280194 SLC44A2/CDS1 2 GO:0015850 organic hydroxy compound transport 9/742 284/18722 0.797397897357008 0.851891352280194 LRP1/CAV1/SLC6A4/SLC5A3/SYT7/KDM5B/NFKBIA/SLC16A1/CYP19A1 9 GO:0002833 positive regulation of response to biotic stimulus 5/742 168/18722 0.800367237616965 0.854878735962769 GRN/CADM1/PRKDC/PUM1/LAMP1 5 GO:0050864 regulation of B cell activation 6/742 198/18722 0.80138276530811 0.855471552249338 SLC39A10/TFRC/MIF/ZFP36L1/CD81/RIF1 6 GO:0009582 detection of abiotic stimulus 4/742 138/18722 0.801547612030366 0.855471552249338 NMT1/CDS1/GNAQ/NR2F6 4 GO:0010543 regulation of platelet activation 1/742 40/18722 0.801961287139005 0.855471552249338 IL6ST 1 GO:0032892 positive regulation of organic acid transport 1/742 40/18722 0.801961287139005 0.855471552249338 ITGB1 1 GO:0034122 negative regulation of toll-like receptor signaling pathway 1/742 40/18722 0.801961287139005 0.855471552249338 LGR4 1 GO:0035329 hippo signaling 1/742 40/18722 0.801961287139005 0.855471552249338 DLG5 1 GO:0006323 DNA packaging 6/742 199/18722 0.805197547506732 0.858738317073242 ATRX/NPM1/BRD2/HP1BP3/RSF1/BANF1 6 GO:0140053 mitochondrial gene expression 3/742 108/18722 0.806801808090462 0.860263529455403 IARS2/TUFM/MRPS6 3 GO:0014823 response to activity 2/742 76/18722 0.809231316530153 0.861443736633607 COL4A2/PRKDC 2 GO:2000379 positive regulation of reactive oxygen species metabolic process 2/742 76/18722 0.809231316530153 0.861443736633607 EGFR/SLC5A3 2 GO:0006418 tRNA aminoacylation for protein translation 1/742 41/18722 0.809826864964872 0.861443736633607 IARS2 1 GO:0007099 centriole replication 1/742 41/18722 0.809826864964872 0.861443736633607 NPM1 1 GO:0009167 purine ribonucleoside monophosphate metabolic process 1/742 41/18722 0.809826864964872 0.861443736633607 DLG1 1 GO:0032733 positive regulation of interleukin-10 production 1/742 41/18722 0.809826864964872 0.861443736633607 CD46 1 GO:0032735 positive regulation of interleukin-12 production 1/742 41/18722 0.809826864964872 0.861443736633607 ISL1 1 GO:0044786 cell cycle DNA replication 1/742 41/18722 0.809826864964872 0.861443736633607 ATRX 1 GO:0048634 regulation of muscle organ development 1/742 41/18722 0.809826864964872 0.861443736633607 IGF2 1 GO:0055023 positive regulation of cardiac muscle tissue growth 1/742 41/18722 0.809826864964872 0.861443736633607 TGFBR3 1 GO:2000008 regulation of protein localization to cell surface 1/742 41/18722 0.809826864964872 0.861443736633607 LEPROT 1 GO:0065004 protein-DNA complex assembly 6/742 201/18722 0.812655986737064 0.864267077390978 ATRX/NPM1/BDP1/BRD2/HP1BP3/RSF1 6 GO:0140056 organelle localization by membrane tethering 2/742 77/18722 0.814985528157586 0.866121709187541 CALM1/CLN3 2 GO:0048515 spermatid differentiation 5/742 172/18722 0.816484091211721 0.866121709187541 DYNLL1/JAM3/AFF4/CELF1/SMARCA2 5 GO:0044282 small molecule catabolic process 12/742 376/18722 0.816682990203078 0.866121709187541 GLDC/SLC27A2/LRP5/ATP2B4/TPI1/CROT/ENO1/GLB1/ACADVL/FUT8/HADHA/ETFA 12 GO:0006040 amino sugar metabolic process 1/742 42/18722 0.817380447010591 0.866121709187541 EXTL2 1 GO:0007212 dopamine receptor signaling pathway 1/742 42/18722 0.817380447010591 0.866121709187541 NCSTN 1 GO:0007520 myoblast fusion 1/742 42/18722 0.817380447010591 0.866121709187541 CD81 1 GO:0010677 negative regulation of cellular carbohydrate metabolic process 1/742 42/18722 0.817380447010591 0.866121709187541 NCOR1 1 GO:0014003 oligodendrocyte development 1/742 42/18722 0.817380447010591 0.866121709187541 NCSTN 1 GO:0032691 negative regulation of interleukin-1 beta production 1/742 42/18722 0.817380447010591 0.866121709187541 SERPINB1 1 GO:0032965 regulation of collagen biosynthetic process 1/742 42/18722 0.817380447010591 0.866121709187541 SUCO 1 GO:0042168 heme metabolic process 1/742 42/18722 0.817380447010591 0.866121709187541 BLVRA 1 GO:0045292 mRNA cis splicing, via spliceosome 1/742 42/18722 0.817380447010591 0.866121709187541 SNRPC 1 GO:0046596 regulation of viral entry into host cell 1/742 42/18722 0.817380447010591 0.866121709187541 P4HB 1 GO:0048489 synaptic vesicle transport 1/742 42/18722 0.817380447010591 0.866121709187541 KIF5B 1 GO:0071312 cellular response to alkaloid 1/742 42/18722 0.817380447010591 0.866121709187541 TGM2 1 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis 1/742 42/18722 0.817380447010591 0.866121709187541 RHOA 1 GO:1904037 positive regulation of epithelial cell apoptotic process 1/742 42/18722 0.817380447010591 0.866121709187541 PDCD4 1 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 2/742 78/18722 0.820584069644344 0.869143504297397 S100A9/PMAIP1 2 GO:0009064 glutamine family amino acid metabolic process 2/742 78/18722 0.820584069644344 0.869143504297397 ATP2B4/CLN3 2 GO:0006805 xenobiotic metabolic process 3/742 111/18722 0.82133224644239 0.869563072744408 GSTO1/POR/CYP2J2 3 GO:0015718 monocarboxylic acid transport 3/742 111/18722 0.82133224644239 0.869563072744408 ANXA1/SLC16A12/SLC16A1 3 GO:0006284 base-excision repair 1/742 43/18722 0.824634392852033 0.871751316218498 HUWE1 1 GO:0032365 intracellular lipid transport 1/742 43/18722 0.824634392852033 0.871751316218498 SYT7 1 GO:0034142 toll-like receptor 4 signaling pathway 1/742 43/18722 0.824634392852033 0.871751316218498 NFKBIA 1 GO:0034661 ncRNA catabolic process 1/742 43/18722 0.824634392852033 0.871751316218498 KCNQ1OT1 1 GO:0042088 T-helper 1 type immune response 1/742 43/18722 0.824634392852033 0.871751316218498 ANXA1 1 GO:0045494 photoreceptor cell maintenance 1/742 43/18722 0.824634392852033 0.871751316218498 SLC2A1 1 GO:0098815 modulation of excitatory postsynaptic potential 1/742 43/18722 0.824634392852033 0.871751316218498 APP 1 GO:0002526 acute inflammatory response 3/742 112/18722 0.825964422693156 0.87248007154546 IL6ST/ASH1L/GATA3 3 GO:0032609 interferon-gamma production 3/742 112/18722 0.825964422693156 0.87248007154546 ISL1/DDIT3/GATA3 3 GO:0032649 regulation of interferon-gamma production 3/742 112/18722 0.825964422693156 0.87248007154546 ISL1/DDIT3/GATA3 3 GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 2/742 79/18722 0.826030221582614 0.87248007154546 GAPDH/S100A9 2 GO:0006887 exocytosis 11/742 352/18722 0.828873487355147 0.875296072581109 ATP6AP1/MIA3/ANXA1/SYT7/VAMP2/SDF4/LAMP1/CALM1/RAB11A/ANXA3/SDCBP 11 GO:0071347 cellular response to interleukin-1 3/742 113/18722 0.830493532965772 0.87574223641483 EGR1/USP10/YY1 3 GO:0046395 carboxylic acid catabolic process 7/742 236/18722 0.830668562808811 0.87574223641483 GLDC/SLC27A2/ATP2B4/CROT/ACADVL/HADHA/ETFA 7 GO:0071229 cellular response to acid chemical 2/742 80/18722 0.831327249403544 0.87574223641483 PLEC/SLC38A9 2 GO:0007269 neurotransmitter secretion 4/742 145/18722 0.831363313346676 0.87574223641483 PPP1R9A/SYT7/VAMP2/CALM1 4 GO:0099643 signal release from synapse 4/742 145/18722 0.831363313346676 0.87574223641483 PPP1R9A/SYT7/VAMP2/CALM1 4 GO:0006378 mRNA polyadenylation 1/742 44/18722 0.83160057308137 0.87574223641483 APP 1 GO:0009126 purine nucleoside monophosphate metabolic process 1/742 44/18722 0.83160057308137 0.87574223641483 DLG1 1 GO:0032620 interleukin-17 production 1/742 44/18722 0.83160057308137 0.87574223641483 DDIT3 1 GO:0032660 regulation of interleukin-17 production 1/742 44/18722 0.83160057308137 0.87574223641483 DDIT3 1 GO:0042554 superoxide anion generation 1/742 44/18722 0.83160057308137 0.87574223641483 EGFR 1 GO:0043039 tRNA aminoacylation 1/742 44/18722 0.83160057308137 0.87574223641483 IARS2 1 GO:0046006 regulation of activated T cell proliferation 1/742 44/18722 0.83160057308137 0.87574223641483 IGF2 1 GO:0051150 regulation of smooth muscle cell differentiation 1/742 44/18722 0.83160057308137 0.87574223641483 PDCD4 1 GO:0001523 retinoid metabolic process 2/742 81/18722 0.836478399429566 0.879973336128484 LRP2/LRP1 2 GO:0001960 negative regulation of cytokine-mediated signaling pathway 2/742 81/18722 0.836478399429566 0.879973336128484 CAV1/ADAR 2 GO:0010824 regulation of centrosome duplication 1/742 45/18722 0.838290388627661 0.879973336128484 NPM1 1 GO:0032309 icosanoid secretion 1/742 45/18722 0.838290388627661 0.879973336128484 ANXA1 1 GO:0035384 thioester biosynthetic process 1/742 45/18722 0.838290388627661 0.879973336128484 ACSS1 1 GO:0042551 neuron maturation 1/742 45/18722 0.838290388627661 0.879973336128484 APP 1 GO:0043038 amino acid activation 1/742 45/18722 0.838290388627661 0.879973336128484 IARS2 1 GO:0043631 RNA polyadenylation 1/742 45/18722 0.838290388627661 0.879973336128484 APP 1 GO:0044088 regulation of vacuole organization 1/742 45/18722 0.838290388627661 0.879973336128484 GRN 1 GO:0045910 negative regulation of DNA recombination 1/742 45/18722 0.838290388627661 0.879973336128484 RIF1 1 GO:0046189 phenol-containing compound biosynthetic process 1/742 45/18722 0.838290388627661 0.879973336128484 GATA3 1 GO:0060421 positive regulation of heart growth 1/742 45/18722 0.838290388627661 0.879973336128484 TGFBR3 1 GO:0071354 cellular response to interleukin-6 1/742 45/18722 0.838290388627661 0.879973336128484 IL6ST 1 GO:0071616 acyl-CoA biosynthetic process 1/742 45/18722 0.838290388627661 0.879973336128484 ACSS1 1 GO:0098534 centriole assembly 1/742 45/18722 0.838290388627661 0.879973336128484 NPM1 1 GO:0043279 response to alkaloid 3/742 115/18722 0.839248849315111 0.88079229139933 HSPA5/FOSB/TGM2 3 GO:0002312 B cell activation involved in immune response 2/742 82/18722 0.841486895262596 0.88276603580319 TFRC/RIF1 2 GO:0008543 fibroblast growth factor receptor signaling pathway 2/742 82/18722 0.841486895262596 0.88276603580319 GPC1/GATA3 2 GO:0001818 negative regulation of cytokine production 11/742 357/18722 0.841784655894893 0.882890912976809 ATP2B1/LGR4/TMSB4X/ANXA1/DDIT3/GATA3/CHID1/YY1/SERPINB1/ANXA4/PDCD4 11 GO:0016054 organic acid catabolic process 7/742 240/18722 0.843026932541759 0.884006165730479 GLDC/SLC27A2/ATP2B4/CROT/ACADVL/HADHA/ETFA 7 GO:0006720 isoprenoid metabolic process 3/742 116/18722 0.843478224757741 0.884104059050126 LRP2/EGFR/LRP1 3 GO:0043200 response to amino acid 3/742 116/18722 0.843478224757741 0.884104059050126 UFL1/SLC38A9/RHOA 3 GO:0031057 negative regulation of histone modification 1/742 46/18722 0.844714789315046 0.88446186079193 KDM5A 1 GO:0043300 regulation of leukocyte degranulation 1/742 46/18722 0.844714789315046 0.88446186079193 LAMP1 1 GO:0046839 phospholipid dephosphorylation 1/742 46/18722 0.844714789315046 0.88446186079193 PLPP3 1 GO:0061028 establishment of endothelial barrier 1/742 46/18722 0.844714789315046 0.88446186079193 ROCK1 1 GO:0090329 regulation of DNA-dependent DNA replication 1/742 46/18722 0.844714789315046 0.88446186079193 ATRX 1 GO:0050672 negative regulation of lymphocyte proliferation 2/742 83/18722 0.84635593448776 0.885804728044393 DLG5/DLG1 2 GO:0061053 somite development 2/742 83/18722 0.84635593448776 0.885804728044393 PRKDC/RBBP6 2 GO:0046474 glycerophospholipid biosynthetic process 6/742 211/18722 0.846631379737879 0.885905320039213 PISD/GPAA1/SLC44A2/PGAP1/CDS1/CLN3 6 GO:0032640 tumor necrosis factor production 5/742 181/18722 0.84893127326397 0.887935737862378 APP/MIF/ISL1/FOXP1/HSPB1 5 GO:0032680 regulation of tumor necrosis factor production 5/742 181/18722 0.84893127326397 0.887935737862378 APP/MIF/ISL1/FOXP1/HSPB1 5 GO:0006998 nuclear envelope organization 1/742 47/18722 0.850884291688586 0.888311453037482 NEK6 1 GO:0032008 positive regulation of TOR signaling 1/742 47/18722 0.850884291688586 0.888311453037482 SLC38A9 1 GO:0032369 negative regulation of lipid transport 1/742 47/18722 0.850884291688586 0.888311453037482 ITGAV 1 GO:0050798 activated T cell proliferation 1/742 47/18722 0.850884291688586 0.888311453037482 IGF2 1 GO:0051972 regulation of telomerase activity 1/742 47/18722 0.850884291688586 0.888311453037482 PTGES3 1 GO:0090279 regulation of calcium ion import 1/742 47/18722 0.850884291688586 0.888311453037482 VDAC1 1 GO:0097028 dendritic cell differentiation 1/742 47/18722 0.850884291688586 0.888311453037482 DHRS2 1 GO:0009953 dorsal/ventral pattern formation 2/742 84/18722 0.851088685673361 0.888311453037482 GLI3/DDIT3 2 GO:0015844 monoamine transport 2/742 84/18722 0.851088685673361 0.888311453037482 SLC6A4/SYT7 2 GO:0032945 negative regulation of mononuclear cell proliferation 2/742 84/18722 0.851088685673361 0.888311453037482 DLG5/DLG1 2 GO:0097006 regulation of plasma lipoprotein particle levels 2/742 85/18722 0.855688285648843 0.892923559591314 LRPAP1/CNPY2 2 GO:0046486 glycerolipid metabolic process 12/742 392/18722 0.856188964379724 0.89325733559363 CAV1/SERINC1/PISD/GPAA1/SLC44A2/PGAP1/CDS1/SERINC3/HADHA/PRDX6/GPX1/CLN3 12 GO:0030261 chromosome condensation 1/742 48/18722 0.856808996136622 0.893542718544633 BANF1 1 GO:0042113 B cell activation 10/742 334/18722 0.856824262701605 0.893542718544633 SLC39A10/ITGB1/TFRC/MIF/PRKDC/ZFP36L1/CD81/RIF1/YY1/TPD52 10 GO:0006310 DNA recombination 9/742 305/18722 0.857981569962828 0.894560775773822 FUS/TFRC/PRKDC/NIPBL/RIF1/HMGB3/RAD50/PARP1/YY1 9 GO:0007601 visual perception 6/742 215/18722 0.858741346461263 0.895164011715265 EFEMP1/TACSTD2/CRYBG3/TIMP3/ATF6/EPAS1 6 GO:0046928 regulation of neurotransmitter secretion 2/742 86/18722 0.860157837043471 0.896262331785434 PPP1R9A/CALM1 2 GO:0060761 negative regulation of response to cytokine stimulus 2/742 86/18722 0.860157837043471 0.896262331785434 CAV1/ADAR 2 GO:0001913 T cell mediated cytotoxicity 1/742 49/18722 0.862498603337362 0.896998547470856 CTSC 1 GO:0006778 porphyrin-containing compound metabolic process 1/742 49/18722 0.862498603337362 0.896998547470856 BLVRA 1 GO:0008206 bile acid metabolic process 1/742 49/18722 0.862498603337362 0.896998547470856 SLC27A2 1 GO:0009066 aspartate family amino acid metabolic process 1/742 49/18722 0.862498603337362 0.896998547470856 MTR 1 GO:0009994 oocyte differentiation 1/742 49/18722 0.862498603337362 0.896998547470856 LGR5 1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 1/742 49/18722 0.862498603337362 0.896998547470856 SKP1 1 GO:0032692 negative regulation of interleukin-1 production 1/742 49/18722 0.862498603337362 0.896998547470856 SERPINB1 1 GO:0046605 regulation of centrosome cycle 1/742 49/18722 0.862498603337362 0.896998547470856 NPM1 1 GO:0070741 response to interleukin-6 1/742 49/18722 0.862498603337362 0.896998547470856 IL6ST 1 GO:0034470 ncRNA processing 12/742 395/18722 0.862799151757009 0.897122249985187 RPS21/RPS6/RPS16/RPL14/RPL7/RPS25/RPL26/PRKDC/DDX17/RPS17/ADAR/SSB 12 GO:0002455 humoral immune response mediated by circulating immunoglobulin 3/742 121/18722 0.863206109220023 0.897356519264923 CD46/CD81/CD55 3 GO:1901606 alpha-amino acid catabolic process 2/742 87/18722 0.864500406069398 0.898454887027758 GLDC/ATP2B4 2 GO:0071706 tumor necrosis factor superfamily cytokine production 5/742 186/18722 0.864808297128945 0.898454887027758 APP/MIF/ISL1/FOXP1/HSPB1 5 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 5/742 186/18722 0.864808297128945 0.898454887027758 APP/MIF/ISL1/FOXP1/HSPB1 5 GO:0007281 germ cell development 8/742 278/18722 0.865031456616752 0.898497770329426 RPS6/LGR5/DYNLL1/JAM3/AFF4/CELF1/SMARCA2/HEXB 8 GO:0045088 regulation of innate immune response 6/742 218/18722 0.867298152502056 0.899839329376363 GRN/CADM1/PRKDC/LAMP1/ADAR/SERPINB9 6 GO:0002695 negative regulation of leukocyte activation 5/742 187/18722 0.867809707954033 0.899839329376363 GRN/DLG5/ANXA1/GLI3/DLG1 5 GO:0002448 mast cell mediated immunity 1/742 50/18722 0.867962430056351 0.899839329376363 SERPINB9 1 GO:0006220 pyrimidine nucleotide metabolic process 1/742 50/18722 0.867962430056351 0.899839329376363 NME3 1 GO:0010665 regulation of cardiac muscle cell apoptotic process 1/742 50/18722 0.867962430056351 0.899839329376363 PPP1R10 1 GO:0015872 dopamine transport 1/742 50/18722 0.867962430056351 0.899839329376363 SYT7 1 GO:0038202 TORC1 signaling 1/742 50/18722 0.867962430056351 0.899839329376363 LARP1 1 GO:0051646 mitochondrion localization 1/742 50/18722 0.867962430056351 0.899839329376363 ARMCX3 1 GO:0060337 type I interferon signaling pathway 1/742 50/18722 0.867962430056351 0.899839329376363 ADAR 1 GO:1901657 glycosyl compound metabolic process 2/742 88/18722 0.868719020533647 0.900434738026902 FUCA1/GUSB 2 GO:0050953 sensory perception of light stimulus 6/742 219/18722 0.870053086714239 0.901628329844418 EFEMP1/TACSTD2/CRYBG3/TIMP3/ATF6/EPAS1 6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone 1/742 51/18722 0.873209424320392 0.904438285205946 NDUFB9 1 GO:0060632 regulation of microtubule-based movement 1/742 51/18722 0.873209424320392 0.904438285205946 LAMP1 1 GO:0006302 double-strand break repair 7/742 251/18722 0.873313890775782 0.904438285205946 FUS/PRKDC/NIPBL/RIF1/RAD50/PARP1/YY1 7 GO:0051250 negative regulation of lymphocyte activation 4/742 157/18722 0.873762696183907 0.904713418392056 DLG5/ANXA1/GLI3/DLG1 4 GO:0070664 negative regulation of leukocyte proliferation 2/742 90/18722 0.876796294537719 0.907664227790513 DLG5/DLG1 2 GO:0002218 activation of innate immune response 1/742 52/18722 0.878248179992519 0.90859602286137 PRKDC 1 GO:0007129 homologous chromosome pairing at meiosis 1/742 52/18722 0.878248179992519 0.90859602286137 CCNE1 1 GO:0071357 cellular response to type I interferon 1/742 52/18722 0.878248179992519 0.90859602286137 ADAR 1 GO:0009165 nucleotide biosynthetic process 7/742 254/18722 0.880683052400939 0.910924262743015 SLC26A2/ALDOA/ACSS1/TMSB4X/ENO1/NME3/PARP1 7 GO:0032784 regulation of DNA-templated transcription, elongation 1/742 53/18722 0.883086950771605 0.912455456350498 BRD4 1 GO:0033059 cellular pigmentation 1/742 53/18722 0.883086950771605 0.912455456350498 RAB11A 1 GO:0050819 negative regulation of coagulation 1/742 53/18722 0.883086950771605 0.912455456350498 ANXA5 1 GO:0071715 icosanoid transport 1/742 53/18722 0.883086950771605 0.912455456350498 ANXA1 1 GO:0097479 synaptic vesicle localization 1/742 53/18722 0.883086950771605 0.912455456350498 KIF5B 1 GO:0035249 synaptic transmission, glutamatergic 2/742 92/18722 0.884413050916063 0.913443544119873 EGFR/CLN3 2 GO:0070509 calcium ion import 2/742 92/18722 0.884413050916063 0.913443544119873 ATP2B4/VDAC1 2 GO:1901293 nucleoside phosphate biosynthetic process 7/742 256/18722 0.885394985484876 0.914266561098513 SLC26A2/ALDOA/ACSS1/TMSB4X/ENO1/NME3/PARP1 7 GO:0010659 cardiac muscle cell apoptotic process 1/742 54/18722 0.887733663639326 0.91605677800949 PPP1R10 1 GO:0014888 striated muscle adaptation 1/742 54/18722 0.887733663639326 0.91605677800949 ATP2B4 1 GO:2000300 regulation of synaptic vesicle exocytosis 1/742 54/18722 0.887733663639326 0.91605677800949 CALM1 1 GO:0032755 positive regulation of interleukin-6 production 2/742 93/18722 0.888055852203937 0.91605677800949 APP/ISL1 2 GO:0033108 mitochondrial respiratory chain complex assembly 2/742 93/18722 0.888055852203937 0.91605677800949 NDUFB9/COX20 2 GO:1901605 alpha-amino acid metabolic process 5/742 195/18722 0.889852884930884 0.917718841661496 GLDC/ATP2B4/MTR/SERINC3/CLN3 5 GO:0002764 immune response-regulating signaling pathway 14/742 468/18722 0.89106879905571 0.918781020107536 SLC39A10/KCNN4/CAV1/LGR4/COLEC12/RTN4/HSPA1A/CD81/HSPA1B/PUM1/FOXP1/NFKBIA/GATA3/PHPT1 14 GO:0002690 positive regulation of leukocyte chemotaxis 2/742 94/18722 0.891591973257721 0.918984133230723 CALR/LGMN 2 GO:0000768 syncytium formation by plasma membrane fusion 1/742 55/18722 0.892195931776224 0.918984133230723 CD81 1 GO:0046164 alcohol catabolic process 1/742 55/18722 0.892195931776224 0.918984133230723 TPI1 1 GO:0061098 positive regulation of protein tyrosine kinase activity 1/742 55/18722 0.892195931776224 0.918984133230723 ERBB3 1 GO:0140253 cell-cell fusion 1/742 55/18722 0.892195931776224 0.918984133230723 CD81 1 GO:0006661 phosphatidylinositol biosynthetic process 3/742 131/18722 0.896202690982462 0.921860214575597 GPAA1/PGAP1/CDS1 3 GO:0045089 positive regulation of innate immune response 3/742 131/18722 0.896202690982462 0.921860214575597 CADM1/PRKDC/LAMP1 3 GO:0050853 B cell receptor signaling pathway 3/742 131/18722 0.896202690982462 0.921860214575597 SLC39A10/CD81/FOXP1 3 GO:0002886 regulation of myeloid leukocyte mediated immunity 1/742 56/18722 0.896481066967848 0.921860214575597 DHX36 1 GO:0032608 interferon-beta production 1/742 56/18722 0.896481066967848 0.921860214575597 YY1 1 GO:0032648 regulation of interferon-beta production 1/742 56/18722 0.896481066967848 0.921860214575597 YY1 1 GO:0050433 regulation of catecholamine secretion 1/742 56/18722 0.896481066967848 0.921860214575597 SYT7 1 GO:0070534 protein K63-linked ubiquitination 1/742 56/18722 0.896481066967848 0.921860214575597 HECTD1 1 GO:0045055 regulated exocytosis 6/742 230/18722 0.8973242378147 0.922535220562876 SYT7/VAMP2/SDF4/LAMP1/CALM1/ANXA3 6 GO:0015914 phospholipid transport 2/742 96/18722 0.898355005630836 0.923018662191416 KCNN4/ATP10D 2 GO:0042632 cholesterol homeostasis 2/742 96/18722 0.898355005630836 0.923018662191416 CAV1/LRP5 2 GO:0043648 dicarboxylic acid metabolic process 2/742 96/18722 0.898355005630836 0.923018662191416 SLC19A1/FOLR1 2 GO:0006949 syncytium formation 1/742 57/18722 0.900596091521039 0.924167987560019 CD81 1 GO:0010257 NADH dehydrogenase complex assembly 1/742 57/18722 0.900596091521039 0.924167987560019 NDUFB9 1 GO:0030219 megakaryocyte differentiation 1/742 57/18722 0.900596091521039 0.924167987560019 WASF2 1 GO:0032981 mitochondrial respiratory chain complex I assembly 1/742 57/18722 0.900596091521039 0.924167987560019 NDUFB9 1 GO:0051155 positive regulation of striated muscle cell differentiation 1/742 57/18722 0.900596091521039 0.924167987560019 MORF4L2 1 GO:0051289 protein homotetramerization 1/742 57/18722 0.900596091521039 0.924167987560019 ALDOA 1 GO:0055092 sterol homeostasis 2/742 97/18722 0.901587212773606 0.924766328902788 CAV1/LRP5 2 GO:0009451 RNA modification 4/742 167/18722 0.901740770511079 0.924766328902788 RBM47/ZC3H13/ADAR/SSB 4 GO:0055088 lipid homeostasis 4/742 167/18722 0.901740770511079 0.924766328902788 CAV1/ORMDL1/RTN4/LRP5 4 GO:0007131 reciprocal meiotic recombination 1/742 58/18722 0.904547749709701 0.926298897919968 RAD50 1 GO:0009161 ribonucleoside monophosphate metabolic process 1/742 58/18722 0.904547749709701 0.926298897919968 DLG1 1 GO:0010043 response to zinc ion 1/742 58/18722 0.904547749709701 0.926298897919968 PARP1 1 GO:0034340 response to type I interferon 1/742 58/18722 0.904547749709701 0.926298897919968 ADAR 1 GO:0043506 regulation of JUN kinase activity 1/742 58/18722 0.904547749709701 0.926298897919968 PDCD4 1 GO:0050432 catecholamine secretion 1/742 58/18722 0.904547749709701 0.926298897919968 SYT7 1 GO:0140527 reciprocal homologous recombination 1/742 58/18722 0.904547749709701 0.926298897919968 RAD50 1 GO:0048278 vesicle docking 1/742 59/18722 0.908342518768606 0.929799428660778 CLN3 1 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 1/742 59/18722 0.908342518768606 0.929799428660778 CAV1 1 GO:1903305 regulation of regulated secretory pathway 3/742 136/18722 0.909858824820124 0.931158606714608 SYT7/LAMP1/CALM1 3 GO:0006641 triglyceride metabolic process 2/742 100/18722 0.910717354217397 0.931651217609017 CAV1/GPX1 2 GO:0060079 excitatory postsynaptic potential 2/742 100/18722 0.910717354217397 0.931651217609017 APP/PPP1R9A 2 GO:0048469 cell maturation 4/742 171/18722 0.91130367341844 0.932058001384491 APP/GATA3/EPAS1/HES1 4 GO:0006081 cellular aldehyde metabolic process 1/742 60/18722 0.911986619453046 0.932177508813997 TPI1 1 GO:0006289 nucleotide-excision repair 1/742 60/18722 0.911986619453046 0.932177508813997 DDB1 1 GO:0035825 homologous recombination 1/742 60/18722 0.911986619453046 0.932177508813997 RAD50 1 GO:0006576 cellular biogenic amine metabolic process 2/742 101/18722 0.913580166128153 0.933613161082556 GATA3/EPAS1 2 GO:0051259 protein complex oligomerization 6/742 238/18722 0.913945074939992 0.933792899731864 ALDOA/FUS/MIF/SLC1A5/SLC9A1/YME1L1 6 GO:0043966 histone H3 acetylation 1/742 61/18722 0.915486026181469 0.935173897712253 GATA3 1 GO:0034308 primary alcohol metabolic process 2/742 102/18722 0.916356700104523 0.935676332888868 ACSS1/CYP11A1 2 GO:1990542 mitochondrial transmembrane transport 2/742 102/18722 0.916356700104523 0.935676332888868 SLC25A36/VDAC1 2 GO:0034660 ncRNA metabolic process 14/742 485/18722 0.91687842681546 0.935909843853328 RPS21/RPS6/RPS16/RPL14/RPL7/KCNQ1OT1/RPS25/RPL26/PRKDC/IARS2/DDX17/RPS17/ADAR/SSB 14 GO:0016064 immunoglobulin mediated immune response 5/742 207/18722 0.916964300455487 0.935909843853328 CD46/TFRC/CD81/CD55/RIF1 5 GO:0050851 antigen receptor-mediated signaling pathway 6/742 240/18722 0.917716297222431 0.936483889336668 SLC39A10/KCNN4/CD81/FOXP1/GATA3/PHPT1 6 GO:0019933 cAMP-mediated signaling 1/742 62/18722 0.918846476777544 0.937056481271896 ADM 1 GO:0032613 interleukin-10 production 1/742 62/18722 0.918846476777544 0.937056481271896 CD46 1 GO:0032653 regulation of interleukin-10 production 1/742 62/18722 0.918846476777544 0.937056481271896 CD46 1 GO:1905037 autophagosome organization 2/742 103/18722 0.919049286381785 0.937069860624565 RB1CC1/CLN3 2 GO:0071222 cellular response to lipopolysaccharide 5/742 209/18722 0.920861839651768 0.938724203029248 PABPN1/CD55/NFKBIA/RHOA/PDCD4 5 GO:0032006 regulation of TOR signaling 2/742 104/18722 0.921660206312443 0.939344216873008 SLC38A9/GNA12 2 GO:0001756 somitogenesis 1/742 63/18722 0.92207348182744 0.939377809904631 PRKDC 1 GO:0045143 homologous chromosome segregation 1/742 63/18722 0.92207348182744 0.939377809904631 CCNE1 1 GO:0019724 B cell mediated immunity 5/742 210/18722 0.922749315681764 0.939678750663351 CD46/TFRC/CD81/CD55/RIF1 5 GO:0050866 negative regulation of cell activation 5/742 210/18722 0.922749315681764 0.939678750663351 GRN/DLG5/ANXA1/GLI3/DLG1 5 GO:0002440 production of molecular mediator of immune response 8/742 308/18722 0.92497876881276 0.941369995533995 TFRC/PRKDC/CD81/CD55/DHX36/RIF1/GATA3/YY1 8 GO:0046888 negative regulation of hormone secretion 1/742 64/18722 0.925172333667519 0.941369995533995 GJA1 1 GO:0048247 lymphocyte chemotaxis 1/742 64/18722 0.925172333667519 0.941369995533995 PLEC 1 GO:0070542 response to fatty acid 1/742 64/18722 0.925172333667519 0.941369995533995 GLDC 1 GO:0099565 chemical synaptic transmission, postsynaptic 2/742 106/18722 0.926645929445298 0.942675224765192 APP/PPP1R9A 2 GO:0046503 glycerolipid catabolic process 1/742 65/18722 0.928148115017005 0.943814674389462 PRDX6 1 GO:0061512 protein localization to cilium 1/742 65/18722 0.928148115017005 0.943814674389462 TMEM107 1 GO:0030193 regulation of blood coagulation 1/742 66/18722 0.931005707269638 0.946330904097122 CAV1 1 GO:2000272 negative regulation of signaling receptor activity 1/742 66/18722 0.931005707269638 0.946330904097122 LRPAP1 1 GO:0006958 complement activation, classical pathway 2/742 108/18722 0.931331152079629 0.946466959735315 CD46/CD55 2 GO:0051260 protein homooligomerization 4/742 182/18722 0.933466252276558 0.948441646698107 ALDOA/FUS/MIF/SLC1A5 4 GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 1/742 67/18722 0.933749798457778 0.94853465029435 ANXA1 1 GO:0009063 cellular amino acid catabolic process 2/742 110/18722 0.935732393875158 0.94976741848023 GLDC/ATP2B4 2 GO:0030317 flagellated sperm motility 2/742 110/18722 0.935732393875158 0.94976741848023 ATP2B4/ASH1L 2 GO:0097722 sperm motility 2/742 110/18722 0.935732393875158 0.94976741848023 ATP2B4/ASH1L 2 GO:1904659 glucose transmembrane transport 2/742 110/18722 0.935732393875158 0.94976741848023 SLC2A1/SLC5A3 2 GO:1900046 regulation of hemostasis 1/742 68/18722 0.936384890901859 0.950234462008049 CAV1 1 GO:0045017 glycerolipid biosynthetic process 6/742 252/18722 0.937450720488631 0.951120673488157 PISD/GPAA1/SLC44A2/PGAP1/CDS1/CLN3 6 GO:0071219 cellular response to molecule of bacterial origin 5/742 221/18722 0.941020336861797 0.954546296529215 PABPN1/CD55/NFKBIA/RHOA/PDCD4 5 GO:0008643 carbohydrate transport 3/742 152/18722 0.943296553481127 0.956658791664292 SLC2A1/SLC5A3/SLC35B4 3 GO:0071230 cellular response to amino acid stimulus 1/742 71/18722 0.943678565566666 0.956721057181383 SLC38A9 1 GO:0008645 hexose transmembrane transport 2/742 114/18722 0.943745285758073 0.956721057181383 SLC2A1/SLC5A3 2 GO:0090630 activation of GTPase activity 2/742 115/18722 0.945594780208391 0.95839930534047 SYDE2/RABGAP1 2 GO:0032729 positive regulation of interferon-gamma production 1/742 72/18722 0.94591922313728 0.958531479445777 ISL1 1 GO:0015749 monosaccharide transmembrane transport 2/742 116/18722 0.947386298725069 0.959821229635324 SLC2A1/SLC5A3 2 GO:0051298 centrosome duplication 1/742 73/18722 0.948070855117556 0.960120956187111 NPM1 1 GO:0051937 catecholamine transport 1/742 73/18722 0.948070855117556 0.960120956187111 SYT7 1 GO:0046323 glucose import 1/742 74/18722 0.950136994079579 0.961819006301869 SLC2A1 1 GO:1901568 fatty acid derivative metabolic process 1/742 74/18722 0.950136994079579 0.961819006301869 HPGD 1 GO:0034219 carbohydrate transmembrane transport 2/742 118/18722 0.950802095045672 0.962295093121414 SLC2A1/SLC5A3 2 GO:0046488 phosphatidylinositol metabolic process 3/742 159/18722 0.953947904982045 0.965162721761148 GPAA1/PGAP1/CDS1 3 GO:0009123 nucleoside monophosphate metabolic process 1/742 76/18722 0.95402622881775 0.965162721761148 DLG1 1 GO:0006367 transcription initiation from RNA polymerase II promoter 1/742 77/18722 0.955855711721173 0.96661764911005 DHX36 1 GO:0032418 lysosome localization 1/742 77/18722 0.955855711721173 0.96661764911005 KIF5B 1 GO:0019730 antimicrobial humoral response 2/742 122/18722 0.957009218149092 0.967586069925607 GAPDH/S100A9 2 GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 1/742 78/18722 0.9576124862936 0.967601898607156 PSAP 1 GO:0061045 negative regulation of wound healing 1/742 78/18722 0.9576124862936 0.967601898607156 GJA1 1 GO:1901616 organic hydroxy compound catabolic process 1/742 78/18722 0.9576124862936 0.967601898607156 TPI1 1 GO:0060294 cilium movement involved in cell motility 2/742 125/18722 0.961165069287514 0.970973309477369 ATP2B4/ASH1L 2 GO:1903046 meiotic cell cycle process 4/742 202/18722 0.961342197703201 0.970973309477369 ATRX/CALR/RAD50/CCNE1 4 GO:0051149 positive regulation of muscle cell differentiation 1/742 81/18722 0.962474851283162 0.971719960216395 MORF4L2 1 GO:2000243 positive regulation of reproductive process 1/742 81/18722 0.962474851283162 0.971719960216395 CITED2 1 GO:0002253 activation of immune response 9/742 375/18722 0.963957511931286 0.97283034463281 CD46/SLC39A10/KCNN4/PRKDC/CD81/CD55/FOXP1/GATA3/PHPT1 9 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic 1/742 82/18722 0.963968529752552 0.97283034463281 RPS21 1 GO:0006639 acylglycerol metabolic process 2/742 128/18722 0.964934055750149 0.973605848734832 CAV1/GPX1 2 GO:0001510 RNA methylation 1/742 83/18722 0.965402829694806 0.973879922134437 ZC3H13 1 GO:0006638 neutral lipid metabolic process 2/742 129/18722 0.966110371888348 0.974195802638996 CAV1/GPX1 2 GO:0007127 meiosis I 2/742 129/18722 0.966110371888348 0.974195802638996 RAD50/CCNE1 2 GO:0042440 pigment metabolic process 1/742 84/18722 0.966780108538438 0.974672191057119 BLVRA 1 GO:0006956 complement activation 2/742 130/18722 0.967248694942542 0.974945634159592 CD46/CD55 2 GO:0051262 protein tetramerization 1/742 87/18722 0.970592012737796 0.978115981828787 ALDOA 1 GO:0006520 cellular amino acid metabolic process 6/742 284/18722 0.971102023594903 0.97843034806421 GLDC/ATP2B4/IARS2/MTR/SERINC3/CLN3 6 GO:0061982 meiosis I cell cycle process 2/742 135/18722 0.972409855487663 0.97954826388847 RAD50/CCNE1 2 GO:0099024 plasma membrane invagination 2/742 136/18722 0.973343452960313 0.980288819087451 CDC42/RHOA 2 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 8/742 356/18722 0.973583866199378 0.980317264573557 CD46/CTSC/TFRC/CD81/ANXA1/CD55/RIF1/GATA3 8 GO:0002377 immunoglobulin production 4/742 216/18722 0.973926278770382 0.980317264573557 TFRC/PRKDC/RIF1/YY1 4 GO:0006400 tRNA modification 1/742 90/18722 0.973967031280773 0.980317264573557 SSB 1 GO:0019935 cyclic-nucleotide-mediated signaling 1/742 91/18722 0.975003767153984 0.980878196279393 ADM 1 GO:0001539 cilium or flagellum-dependent cell motility 2/742 138/18722 0.975120004438886 0.980878196279393 ATP2B4/ASH1L 2 GO:0060285 cilium-dependent cell motility 2/742 138/18722 0.975120004438886 0.980878196279393 ATP2B4/ASH1L 2 GO:0002429 immune response-activating cell surface receptor signaling pathway 6/742 291/18722 0.975768343492025 0.98113079927755 SLC39A10/KCNN4/CD81/FOXP1/GATA3/PHPT1 6 GO:0002757 immune response-activating signal transduction 6/742 291/18722 0.975768343492025 0.98113079927755 SLC39A10/KCNN4/CD81/FOXP1/GATA3/PHPT1 6 GO:0045132 meiotic chromosome segregation 1/742 93/18722 0.976955176240293 0.982124251246856 CCNE1 1 GO:1903035 negative regulation of response to wounding 1/742 94/18722 0.977873060143332 0.982846982117611 GJA1 1 GO:0051321 meiotic cell cycle 5/742 261/18722 0.979172524981458 0.983772402543066 DUSP1/ATRX/CALR/RAD50/CCNE1 5 GO:0140013 meiotic nuclear division 3/742 185/18722 0.979237740159362 0.983772402543066 CALR/RAD50/CCNE1 3 GO:0006637 acyl-CoA metabolic process 1/742 96/18722 0.979600741448966 0.983772402543066 ACSS1 1 GO:0035383 thioester metabolic process 1/742 96/18722 0.979600741448966 0.983772402543066 ACSS1 1 GO:0010324 membrane invagination 2/742 144/18722 0.979789518322244 0.983772402543066 CDC42/RHOA 2 GO:0000045 autophagosome assembly 1/742 99/18722 0.981942955523839 0.985734241066402 RB1CC1 1 GO:0006910 phagocytosis, recognition 1/742 100/18722 0.982662406042085 0.986256051574137 COLEC12 1 GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 1/742 104/18722 0.985265079785865 0.988466591011814 TGM2 1 GO:0022600 digestive system process 1/742 104/18722 0.985265079785865 0.988466591011814 KCNN4 1 GO:0046434 organophosphate catabolic process 2/742 155/18722 0.986241337980988 0.989245118705803 PLBD1/PRDX6 2 GO:0002768 immune response-regulating cell surface receptor signaling pathway 6/742 315/18722 0.986981433373546 0.989786496318578 SLC39A10/KCNN4/CD81/FOXP1/GATA3/PHPT1 6 GO:0006959 humoral immune response 6/742 317/18722 0.987652538060493 0.990258481432684 GAPDH/CD46/CD81/S100A9/CD55/GATA3 6 GO:0001578 microtubule bundle formation 1/742 113/18722 0.989782402251447 0.992192586672514 CLIP1 1 GO:0032635 interleukin-6 production 2/742 165/18722 0.990334400973419 0.992343192861803 APP/ISL1 2 GO:0032675 regulation of interleukin-6 production 2/742 165/18722 0.990334400973419 0.992343192861803 APP/ISL1 2 GO:0044782 cilium organization 7/742 368/18722 0.991596120051258 0.993405968982603 LAMA5/GALNT11/DYNLL1/CEP350/IFT27/TMEM107/PCM1 7 GO:0060271 cilium assembly 6/742 337/18722 0.992792142547676 0.99440251098652 LAMA5/GALNT11/DYNLL1/CEP350/TMEM107/PCM1 6 GO:0090305 nucleic acid phosphodiester bond hydrolysis 4/742 261/18722 0.993097681731166 0.994438111583015 RPS21/PLD3/N4BP2/RAD50 4 GO:0003341 cilium movement 2/742 175/18722 0.99323029201429 0.994438111583015 ATP2B4/ASH1L 2 GO:0006399 tRNA metabolic process 2/742 179/18722 0.99413367093652 0.994825034481825 IARS2/SSB 2 GO:0006911 phagocytosis, engulfment 1/742 127/18722 0.994220889724043 0.994825034481825 CDC42 1 GO:0008033 tRNA processing 1/742 127/18722 0.994220889724043 0.994825034481825 SSB 1 GO:0007586 digestion 1/742 137/18722 0.996154369900754 0.996557834611123 KCNN4 1 GO:0090501 RNA phosphodiester bond hydrolysis 1/742 152/18722 0.997913371809857 0.998115419465619 RPS21 1 GO:0042742 defense response to bacterium 5/742 350/18722 0.998406475735222 0.998406475735222 GRN/COLEC12/S100A9/FOXP1/ANXA3 5