ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0002181 cytoplasmic translation 16/313 148/18722 3.8039998913132e-09 1.44818275862294e-05 RPS29/RPL37A/RPS27/PKM/RPL23/RPS17/RPL31/RPS21/RPL38/RPS28/RPL4/EIF4H/YBX3/RPL29/EIF4B/TMA7 16 GO:0014706 striated muscle tissue development 24/313 384/18722 3.43200471519197e-08 6.53282097536791e-05 FLNB/IGF2/CAV1/DDX5/LY6E/GPX1/FOS/DSP/YBX3/CAV2/ISL1/PRMT1/RHOA/ITGB1/HMG20B/FHL2/TPM1/BTG2/GJA1/EGR1/TGFBR3/ID2/CCNB1/RGS2 24 GO:0060537 muscle tissue development 24/313 403/18722 8.51037083329498e-08 0.000107996605874513 FLNB/IGF2/CAV1/DDX5/LY6E/GPX1/FOS/DSP/YBX3/CAV2/ISL1/PRMT1/RHOA/ITGB1/HMG20B/FHL2/TPM1/BTG2/GJA1/EGR1/TGFBR3/ID2/CCNB1/RGS2 24 GO:0062197 cellular response to chemical stress 21/313 337/18722 2.65416308346841e-07 0.000252609971469106 CAV1/DHRS2/PAGE4/ANXA1/EFHD1/GPX1/FOS/JUN/YBX3/PRDX1/SOD3/STK24/AKR1B1/HSPA1A/HSPB1/PARP1/TPM1/CLN3/ERRFI1/RHOB/SLC2A1 21 GO:0097193 intrinsic apoptotic signaling pathway 19/313 288/18722 4.19634762448497e-07 0.000319509908128286 CAV1/DDX5/ENO1/PMAIP1/GPX1/MIF/PTTG1IP/YBX3/TNFRSF1A/CEBPB/STK24/HERPUD1/HSPA1A/HSPB1/PARP1/TMBIM6/EIF5A/PPP1R15A/CLU 19 GO:2001242 regulation of intrinsic apoptotic signaling pathway 14/313 164/18722 6.93302479731686e-07 0.000439900423389755 CAV1/ENO1/PMAIP1/GPX1/MIF/PTTG1IP/YBX3/HERPUD1/HSPA1A/HSPB1/PARP1/TMBIM6/EIF5A/CLU 14 GO:2001233 regulation of apoptotic signaling pathway 20/313 356/18722 2.56013451355876e-06 0.00119936491177873 CAV1/ENO1/PMAIP1/GPX1/MIF/TIMP3/PTTG1IP/YBX3/SERPINE1/MAGED1/CTSC/TMBIM1/HERPUD1/HSPA1A/TNFRSF12A/HSPB1/PARP1/TMBIM6/EIF5A/CLU 20 GO:0042060 wound healing 22/313 422/18722 2.74016452956701e-06 0.00119936491177873 CAV1/TFPI2/ACTG1/F5/FN1/ANXA1/GPX1/DSP/SERPINE1/FBLN1/MYH9/CD151/RHOA/CLIC1/ITGB1/DST/TNFRSF12A/HSPB1/TPM1/ACTB/GJA1/FERMT1 22 GO:0006091 generation of precursor metabolites and energy 24/313 490/18722 2.83537804203009e-06 0.00119936491177873 GAPDH/LDHA/ALDOA/CROT/IGF2/PKM/TPI1/DHRS2/PYGL/ENO1/CYP19A1/PHLDA2/IDH1/UGP2/UQCRB/COX4I1/PGAM1/INSR/PGK1/RHOA/AGL/AKR1B1/NDUFB1/CCNB1 24 GO:0071474 cellular hyperosmotic response 5/313 15/18722 3.3108155932367e-06 0.00126042749634521 EFHD1/YBX3/AKR1B1/ERRFI1/SLC2A1 5 GO:0001666 response to hypoxia 18/313 307/18722 4.53134793752181e-06 0.00144792567764992 LDHA/CAV1/MALAT1/STC2/ENO1/PMAIP1/VEGFB/BACH1/SOD3/PGF/PGK1/RHOA/TMBIM6/EGR1/TGFBR3/SLC2A1/DNMT3A/CCNB1 18 GO:0046034 ATP metabolic process 17/313 277/18722 4.56398952765932e-06 0.00144792567764992 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/UQCRB/COX4I1/PGAM1/INSR/PGK1/RHOA/TMSB4X/HSPA1A/PARP1/NDUFB1/CCNB1 17 GO:0001890 placenta development 12/313 144/18722 5.59279607128965e-06 0.00153446708469165 KRT19/HTRA1/KRT8/IGF2/STC2/PHLDA2/BSG/CEBPB/GJA1/ITGB8/MAP3K4/HES1 12 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 10/313 98/18722 5.64290496077832e-06 0.00153446708469165 ENO1/GPX1/MIF/PTTG1IP/YBX3/HERPUD1/HSPA1A/HSPB1/TMBIM6/CLU 10 GO:0051146 striated muscle cell differentiation 17/313 283/18722 6.06895887316452e-06 0.00154030176200916 KRT19/KRT8/IGF2/ACTG1/ADAM12/GPX1/CAV2/ISL1/MYH9/MORF4L2/ITGB1/FHL2/YBX1/TPM1/BHLHE41/CCNB1/RGS2 17 GO:0006096 glycolytic process 9/313 81/18722 8.25786680707325e-06 0.001933419285287 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGAM1/INSR/PGK1 9 GO:0036293 response to decreased oxygen levels 18/313 322/18722 8.74260486861804e-06 0.001933419285287 LDHA/CAV1/MALAT1/STC2/ENO1/PMAIP1/VEGFB/BACH1/SOD3/PGF/PGK1/RHOA/TMBIM6/EGR1/TGFBR3/SLC2A1/DNMT3A/CCNB1 18 GO:0006757 ATP generation from ADP 9/313 82/18722 9.14146234178252e-06 0.001933419285287 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGAM1/INSR/PGK1 9 GO:0007517 muscle organ development 18/313 327/18722 1.07824192634181e-05 0.00215566249700152 FLNB/IGF2/CAV1/DDX5/LY6E/GPX1/FOS/DSP/YBX3/SRI/CAV2/ISL1/RHOA/HMG20B/TPM1/BTG2/EGR1/TGFBR3 18 GO:0006090 pyruvate metabolic process 10/313 106/18722 1.14092847366651e-05 0.00215566249700152 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGAM1/INSR/PGK1/MPC2 10 GO:0007519 skeletal muscle tissue development 12/313 155/18722 1.18909672805442e-05 0.00215566249700152 FLNB/IGF2/CAV1/DDX5/GPX1/FOS/YBX3/CAV2/RHOA/HMG20B/BTG2/EGR1 12 GO:0050673 epithelial cell proliferation 21/313 437/18722 1.59788738020926e-05 0.00276507148020757 HTRA1/IGF2/CAV1/NRP2/GPX1/PDCD6/SERPINB1/CAV2/VEGFB/ISL1/PGF/MAGED1/CEBPB/FLT1/LGR5/GJA1/ERRFI1/TGFBR3/ID2/FERMT1/HES1 21 GO:0003205 cardiac chamber development 12/313 161/18722 1.74470873305507e-05 0.00288787223771333 NRP2/LY6E/DSP/LMO4/ADAMTS6/ISL1/SOX4/FHL2/TPM1/TGFBR3/ADAMTS1/HES1 12 GO:0046031 ADP metabolic process 9/313 90/18722 1.96026965774361e-05 0.0031094777445958 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGAM1/INSR/PGK1 9 GO:0006979 response to oxidative stress 21/313 446/18722 2.1623398158027e-05 0.00313712529331327 GPX3/LDHA/DHRS2/PAGE4/ANXA1/GPX1/FOS/JUN/IDH1/PRDX1/GPX4/SOD3/DHCR24/STK24/HSPA1A/HSPB1/PARP1/TPM1/PRDX6/TRA2B/RHOB 21 GO:0035633 maintenance of blood-brain barrier 6/313 35/18722 2.24513436783284e-05 0.00313712529331327 ACTG1/ITGB1/LSR/ACTB/GJA1/JAM3 6 GO:0060538 skeletal muscle organ development 12/313 166/18722 2.36878572048305e-05 0.00313712529331327 FLNB/IGF2/CAV1/DDX5/GPX1/FOS/YBX3/CAV2/RHOA/HMG20B/BTG2/EGR1 12 GO:0090257 regulation of muscle system process 15/313 252/18722 2.38236048933029e-05 0.00313712529331327 CAV1/ENO1/GSTO1/ATP2B1/DSP/TNFRSF1A/SRI/C12orf57/RHOA/PDE4B/PARP1/TPM1/CALM1/ERRFI1/RGS2 15 GO:0070482 response to oxygen levels 18/313 347/18722 2.38971981891476e-05 0.00313712529331327 LDHA/CAV1/MALAT1/STC2/ENO1/PMAIP1/VEGFB/BACH1/SOD3/PGF/PGK1/RHOA/TMBIM6/EGR1/TGFBR3/SLC2A1/DNMT3A/CCNB1 18 GO:0042692 muscle cell differentiation 19/313 384/18722 2.72938038616578e-05 0.00346358371004438 KRT19/KRT8/IGF2/ACTG1/ADAM12/GPX1/CAV2/ISL1/MYH9/MORF4L2/ITGB1/FHL2/YBX1/TPM1/BHLHE41/ID2/CCNB1/RGS2/HES1 19 GO:0006937 regulation of muscle contraction 12/313 169/18722 2.82983503969647e-05 0.00347521999874982 CAV1/ENO1/GSTO1/ATP2B1/DSP/SRI/C12orf57/RHOA/PDE4B/TPM1/CALM1/RGS2 12 GO:0007179 transforming growth factor beta receptor signaling pathway 13/313 198/18722 3.02084943046581e-05 0.0035938668068073 PEG10/HTRA1/CAV1/FBN1/FOS/JUN/CAV2/NREP/HSPA1A/PARP1/ITGB8/TGFBR3/FERMT1 13 GO:0045216 cell-cell junction organization 13/313 200/18722 3.35532594357986e-05 0.00387082602036622 CAV1/ACTG1/DSP/PKP3/RHOA/LSR/SVEP1/CTNND1/ACTB/GJA1/JAM3/EPB41L3/CLDN7 13 GO:0007043 cell-cell junction assembly 11/313 146/18722 3.53412150075063e-05 0.00395458034969424 CAV1/ACTG1/PKP3/RHOA/LSR/CTNND1/ACTB/GJA1/JAM3/EPB41L3/CLDN7 11 GO:0003206 cardiac chamber morphogenesis 10/313 121/18722 3.63567933384025e-05 0.00395458034969424 NRP2/LY6E/DSP/ISL1/SOX4/FHL2/TPM1/TGFBR3/ADAMTS1/HES1 10 GO:1902850 microtubule cytoskeleton organization involved in mitosis 11/313 147/18722 3.76400947843678e-05 0.0039804400234469 NEK6/CCSAP/RHOA/ITGB1/HSPA1A/TACC2/CDC20/GJA1/STMN1/PLK2/CCNB1 11 GO:0032970 regulation of actin filament-based process 19/313 396/18722 4.14610410083888e-05 0.00422154653248731 CAV1/ACTG1/DSP/COTL1/PFN1/SRI/PHPT1/MYH9/RHOA/TMSB4X/SCIN/S100A10/PDE4B/TPM1/JAM3/STMN1/IQGAP2/RHOB/KANK4 19 GO:0006165 nucleoside diphosphate phosphorylation 9/313 99/18722 4.21378429825368e-05 0.00422154653248731 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGAM1/INSR/PGK1 9 GO:0034637 cellular carbohydrate biosynthetic process 8/313 78/18722 4.73953276424391e-05 0.00440671784604253 IGF2/UGP2/INSR/AGL/AKR1B1/ISYNA1/PGP/B3GNT2 8 GO:0046939 nucleotide phosphorylation 9/313 101/18722 4.93753389787369e-05 0.00440671784604253 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGAM1/INSR/PGK1 9 GO:0006941 striated muscle contraction 12/313 179/18722 4.97623060207497e-05 0.00440671784604253 ALDOA/CAV1/GSTO1/DSP/SRI/VEGFB/C12orf57/PDE4B/TPM1/CALM1/GJA1/RGS2 12 GO:0001667 ameboidal-type cell migration 21/313 475/18722 5.40257477490161e-05 0.00440671784604253 EFNB1/FN1/NRP2/ANXA1/GPX1/PFN1/PDCD6/SEMA6D/ISL1/MYH9/RHOA/ITGB1/TMSB4X/HSPB1/CLN3/GJA1/S100P/RHOB/PLK2/FERMT1/LGMN 21 GO:0015849 organic acid transport 16/313 303/18722 5.47870156559777e-05 0.00440671784604253 CROT/PLIN2/ANXA1/SLC7A5/SLC27A2/SLC16A1/SLC26A2/SERINC5/ITGB1/SLC13A3/SLC43A2/MPC2/CLN3/GJA1/SLC2A1/RGS2 16 GO:0045766 positive regulation of angiogenesis 12/313 181/18722 5.54354282713528e-05 0.00440671784604253 PKM/ADAM12/PDCD6/SERPINE1/VEGFB/ISL1/PGF/ITGB1/FLT1/HSPB1/ITGB8/RHOB 12 GO:1904018 positive regulation of vasculature development 12/313 181/18722 5.54354282713528e-05 0.00440671784604253 PKM/ADAM12/PDCD6/SERPINE1/VEGFB/ISL1/PGF/ITGB1/FLT1/HSPB1/ITGB8/RHOB 12 GO:0071470 cellular response to osmotic stress 6/313 41/18722 5.71685397780675e-05 0.00440671784604253 EFHD1/YBX3/AKR1B1/CLN3/ERRFI1/SLC2A1 6 GO:0009135 purine nucleoside diphosphate metabolic process 9/313 103/18722 5.76349476005503e-05 0.00440671784604253 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGAM1/INSR/PGK1 9 GO:0009179 purine ribonucleoside diphosphate metabolic process 9/313 103/18722 5.76349476005503e-05 0.00440671784604253 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGAM1/INSR/PGK1 9 GO:0016052 carbohydrate catabolic process 11/313 154/18722 5.76486778522176e-05 0.00440671784604253 GAPDH/LDHA/ALDOA/PKM/TPI1/PYGL/ENO1/PGAM1/INSR/PGK1/AGL 11 GO:0060047 heart contraction 14/313 241/18722 5.78765149204431e-05 0.00440671784604253 CYP2J2/CAV1/GSTO1/GPX1/ATP2B1/DSP/SRI/VEGFB/ISL1/PDE4B/TPM1/CALM1/GJA1/RGS2 14 GO:0055001 muscle cell development 12/313 184/18722 6.49913914725579e-05 0.00485141622227506 KRT19/KRT8/ACTG1/GPX1/CAV2/ISL1/ITGB1/FHL2/TPM1/CCNB1/RGS2/HES1 12 GO:0009185 ribonucleoside diphosphate metabolic process 9/313 106/18722 7.21902308863254e-05 0.00528515786508155 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGAM1/INSR/PGK1 9 GO:0043434 response to peptide hormone 19/313 414/18722 7.50405703143021e-05 0.00539017832427449 IGF2/PKM/CAV1/CYP11A1/FBN1/STC2/ANXA1/ATP2B1/BSG/CAV2/INSR/PTPRA/PARP1/BTG2/GJA1/ERRFI1/EGR1/TGFBR3/SLC2A1 19 GO:0007229 integrin-mediated signaling pathway 9/313 107/18722 7.76810014836134e-05 0.00547651060459474 FN1/CD63/MYH9/ITGB1/DST/PTPRA/ITGB8/ADAMTS1/FERMT1 9 GO:0003012 muscle system process 20/313 452/18722 8.03774259274597e-05 0.00553905641744541 ALDOA/SLC6A8/CAV1/ENO1/GSTO1/ATP2B1/DSP/TNFRSF1A/SRI/VEGFB/C12orf57/RHOA/TPM4/PDE4B/PARP1/TPM1/CALM1/GJA1/ERRFI1/RGS2 20 GO:0006936 muscle contraction 17/313 347/18722 8.1478108583384e-05 0.00553905641744541 ALDOA/SLC6A8/CAV1/ENO1/GSTO1/ATP2B1/DSP/SRI/VEGFB/C12orf57/RHOA/TPM4/PDE4B/TPM1/CALM1/GJA1/RGS2 17 GO:0071560 cellular response to transforming growth factor beta stimulus 14/313 250/18722 8.57608435053873e-05 0.00572792160043876 PEG10/HTRA1/CAV1/FBN1/FOS/JUN/CAV2/NREP/HSPA1A/PARP1/ITGB8/TGFBR3/NR3C1/FERMT1 14 GO:0003015 heart process 14/313 251/18722 8.9483401999772e-05 0.00584887240184239 CYP2J2/CAV1/GSTO1/GPX1/ATP2B1/DSP/SRI/VEGFB/ISL1/PDE4B/TPM1/CALM1/GJA1/RGS2 14 GO:0006972 hyperosmotic response 5/313 28/18722 9.06444632804573e-05 0.00584887240184239 EFHD1/YBX3/AKR1B1/ERRFI1/SLC2A1 5 GO:0050714 positive regulation of protein secretion 10/313 137/18722 0.000104206573160975 0.00644809518507158 WLS/DYNLL1/SRI/ISL1/SOX4/PHPT1/EZR/MPC2/GJA1/EXOC1 10 GO:0060048 cardiac muscle contraction 10/313 137/18722 0.000104206573160975 0.00644809518507158 CAV1/GSTO1/DSP/SRI/VEGFB/PDE4B/TPM1/CALM1/GJA1/RGS2 10 GO:0052547 regulation of peptidase activity 20/313 461/18722 0.000105012319798907 0.00644809518507158 GAPDH/SERPINB9/CAV1/TFPI2/FN1/PMAIP1/TIMP2/ITIH5/GPX1/TIMP3/PDCD6/SERPINB1/SERPINE1/FBLN1/DHCR24/RHOA/PTTG1/HERPUD1/BIRC5/LGMN 20 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 17/313 355/18722 0.00010744549067178 0.00649277750773754 PEG10/HTRA1/CAV1/FBN1/DDX5/FOS/JUN/CAV2/NREP/FKBP8/HSPA1A/PARP1/ITGB8/EGR1/TGFBR3/FERMT1/HES1 17 GO:0071559 response to transforming growth factor beta 14/313 256/18722 0.000110282081069475 0.00656006066611705 PEG10/HTRA1/CAV1/FBN1/FOS/JUN/CAV2/NREP/HSPA1A/PARP1/ITGB8/TGFBR3/NR3C1/FERMT1 14 GO:0031032 actomyosin structure organization 12/313 196/18722 0.00011882557175755 0.00679004744328609 KRT19/KRT8/ACTG1/PFN1/MYH9/RHOA/ITGB1/S100A10/TPM1/FRMD6/STMN1/EPB41L3 12 GO:0010649 regulation of cell communication by electrical coupling 4/313 16/18722 0.000118997236457382 0.00679004744328609 CAV1/SRI/CALM1/GJA1 4 GO:0031960 response to corticosteroid 11/313 167/18722 0.000119499127580816 0.00679004744328609 ANXA1/FOS/ATP2B1/FOSB/ISL1/RHOA/AGL/PARP1/CALM1/ERRFI1/NR3C1 11 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 6/313 47/18722 0.000125508851111169 0.00702664994382675 JUN/BACH1/CEBPB/HSPA1A/TMBIM6/EGR1 6 GO:0019693 ribose phosphate metabolic process 18/313 396/18722 0.000130543867942261 0.00716747860619998 GAPDH/LDHA/ALDOA/CROT/PKM/TPI1/PYGL/ENO1/PGAM1/SLC26A2/INSR/PGK1/RHOA/TMSB4X/PDE4B/PARP1/MPC2/TECR 18 GO:0034109 homotypic cell-cell adhesion 8/313 90/18722 0.000131789730085106 0.00716747860619998 ACTG1/FN1/DSP/CD99/MYH9/CLIC1/HSPB1/ACTB 8 GO:0038084 vascular endothelial growth factor signaling pathway 6/313 49/18722 0.000158939930935185 0.00852231432493307 NRP2/CD63/VEGFB/PGF/FLT1/HSPB1 6 GO:0009150 purine ribonucleotide metabolic process 17/313 368/18722 0.000165257118539844 0.00873797014279424 GAPDH/LDHA/ALDOA/CROT/PKM/TPI1/ENO1/PGAM1/SLC26A2/INSR/PGK1/RHOA/TMSB4X/PDE4B/PARP1/MPC2/TECR 17 GO:0007052 mitotic spindle organization 9/313 120/18722 0.000187529221817145 0.00963280828322163 NEK6/CCSAP/RHOA/HSPA1A/TACC2/CDC20/STMN1/PLK2/CCNB1 9 GO:0008016 regulation of heart contraction 12/313 206/18722 0.000189407625394475 0.00963280828322163 CYP2J2/CAV1/GSTO1/ATP2B1/DSP/SRI/ISL1/PDE4B/TPM1/CALM1/GJA1/RGS2 12 GO:0051222 positive regulation of protein transport 15/313 303/18722 0.000189781411083144 0.00963280828322163 WLS/DYNLL1/TCAF1/SRI/ICE1/ISL1/SOX4/PHPT1/OAZ1/EZR/MPC2/CLN3/GJA1/NMT1/EXOC1 15 GO:0006942 regulation of striated muscle contraction 8/313 95/18722 0.000192301925275767 0.00963280828322163 CAV1/GSTO1/DSP/SRI/C12orf57/PDE4B/CALM1/RGS2 8 GO:0051384 response to glucocorticoid 10/313 148/18722 0.000197001792570764 0.00969701077208254 ANXA1/FOS/ATP2B1/FOSB/ISL1/RHOA/AGL/CALM1/ERRFI1/NR3C1 10 GO:0071453 cellular response to oxygen levels 11/313 177/18722 0.000199381326791414 0.00969701077208254 CAV1/MALAT1/STC2/ENO1/PMAIP1/BACH1/PGK1/TMBIM6/EGR1/DNMT3A/CCNB1 11 GO:0048545 response to steroid hormone 16/313 339/18722 0.000201225072496591 0.00969701077208254 CAV1/LBH/DDX5/ANXA1/FOS/ATP2B1/IDH1/FOSB/ISL1/UBA5/RHOA/AGL/PARP1/CALM1/ERRFI1/NR3C1 16 GO:0035924 cellular response to vascular endothelial growth factor stimulus 7/313 73/18722 0.0002163346677077 0.0102948259995402 NRP2/ANXA1/CD63/VEGFB/PGF/FLT1/HSPB1 7 GO:0071456 cellular response to hypoxia 10/313 151/18722 0.000231902764698892 0.0108545521331652 MALAT1/STC2/ENO1/PMAIP1/BACH1/PGK1/TMBIM6/EGR1/DNMT3A/CCNB1 10 GO:0051346 negative regulation of hydrolase activity 17/313 379/18722 0.000233799126587745 0.0108545521331652 GAPDH/SERPINB9/TFPI2/ANXA1/TIMP2/ITIH5/GPX1/TIMP3/SERPINB1/SERPINE1/DHCR24/PTTG1/HERPUD1/TMBIM6/BIRC5/PPP1R15A/RGS2 17 GO:0009132 nucleoside diphosphate metabolic process 9/313 124/18722 0.000240112394302062 0.0110133480133488 GAPDH/LDHA/ALDOA/PKM/TPI1/ENO1/PGAM1/INSR/PGK1 9 GO:0043620 regulation of DNA-templated transcription in response to stress 6/313 53/18722 0.000246735246293609 0.0111823938409496 JUN/BACH1/CEBPB/HSPA1A/TMBIM6/EGR1 6 GO:0007051 spindle organization 11/313 184/18722 0.000279000555168359 0.0124270525027271 NEK6/CCSAP/EZR/MYH9/RHOA/HSPA1A/TACC2/CDC20/STMN1/PLK2/CCNB1 11 GO:0009259 ribonucleotide metabolic process 17/313 385/18722 0.000280726691682303 0.0124270525027271 GAPDH/LDHA/ALDOA/CROT/PKM/TPI1/ENO1/PGAM1/SLC26A2/INSR/PGK1/RHOA/TMSB4X/PDE4B/PARP1/MPC2/TECR 17 GO:1903364 positive regulation of cellular protein catabolic process 10/313 155/18722 0.000286378719418883 0.0125315377566401 CAV1/PTTG1IP/DDA1/EZR/CTSC/HERPUD1/HSPA1A/CDC20/CLU/PLK2 10 GO:0010523 negative regulation of calcium ion transport into cytosol 4/313 20/18722 0.000300489169438057 0.0125956131769859 GSTO1/SRI/TMBIM6/CALM1 4 GO:0048608 reproductive structure development 18/313 424/18722 0.000301150756248641 0.0125956131769859 KRT19/HTRA1/KRT8/IGF2/STC2/ANXA1/CYP19A1/PHLDA2/YBX3/IDH1/BSG/DHCR24/CEBPB/GJA1/ITGB8/MAP3K4/ADAMTS1/HES1 18 GO:0055117 regulation of cardiac muscle contraction 7/313 77/18722 0.000301653891497232 0.0125956131769859 CAV1/GSTO1/DSP/SRI/PDE4B/CALM1/RGS2 7 GO:0003229 ventricular cardiac muscle tissue development 6/313 55/18722 0.00030297792354472 0.0125956131769859 LY6E/DSP/ISL1/TPM1/TGFBR3/ID2 6 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 9/313 128/18722 0.000304385713759576 0.0125956131769859 PEG10/HTRA1/CAV1/FBN1/CAV2/NREP/HSPA1A/TGFBR3/FERMT1 9 GO:0044262 cellular carbohydrate metabolic process 14/313 283/18722 0.000311069158629475 0.01262291720946 IGF2/TPI1/PYGL/PMAIP1/PHLDA2/IDH1/UGP2/PGAM1/INSR/AGL/AKR1B1/ISYNA1/PGP/B3GNT2 14 GO:0051385 response to mineralocorticoid 5/313 36/18722 0.000311676968134815 0.01262291720946 FOS/ATP2B1/FOSB/PARP1/CALM1 5 GO:0002262 myeloid cell homeostasis 10/313 157/18722 0.000317395539113264 0.012649150491426 RPS17/ANXA1/PRDX1/PRMT1/UBA5/PDE4B/HSPA1A/JAM3/TGFBR3/ID2 10 GO:0015711 organic anion transport 16/313 354/18722 0.000326489712947325 0.012649150491426 SLC6A8/ANXA1/SLC7A5/SLC16A1/SLC26A2/SERINC5/ITGB1/SLC22A11/SLC13A3/SLC43A2/MPC2/CLN3/CYB5R1/GJA1/SLC2A1/RGS2 16 GO:0032024 positive regulation of insulin secretion 7/313 78/18722 0.000326721637229394 0.012649150491426 DYNLL1/SRI/ISL1/SOX4/PHPT1/MPC2/GJA1 7 GO:0061458 reproductive system development 18/313 427/18722 0.000327713259106538 0.012649150491426 KRT19/HTRA1/KRT8/IGF2/STC2/ANXA1/CYP19A1/PHLDA2/YBX3/IDH1/BSG/DHCR24/CEBPB/GJA1/ITGB8/MAP3K4/ADAMTS1/HES1 18 GO:1904951 positive regulation of establishment of protein localization 15/313 319/18722 0.000329316375893683 0.012649150491426 WLS/DYNLL1/TCAF1/SRI/ICE1/ISL1/SOX4/PHPT1/OAZ1/EZR/MPC2/CLN3/GJA1/NMT1/EXOC1 15 GO:0009746 response to hexose 12/313 219/18722 0.00033226032286383 0.012649150491426 LDHA/KRT18/DYNLL1/SRI/SOX4/PHPT1/RHOA/MPC2/GJA1/HMGN3/TRA2B/EGR1 12 GO:0010951 negative regulation of endopeptidase activity 13/313 252/18722 0.000340012616130866 0.0128161191050516 GAPDH/SERPINB9/TFPI2/TIMP2/ITIH5/GPX1/TIMP3/SERPINB1/SERPINE1/DHCR24/PTTG1/HERPUD1/BIRC5 13 GO:0097529 myeloid leukocyte migration 12/313 220/18722 0.000346278544242601 0.0129243374307018 ANXA1/MIF/CD99/BSG/SERPINE1/VEGFB/CSF3R/PGF/PDE4B/FLT1/JAM3/LGMN 12 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 9/313 131/18722 0.000361412896463524 0.0133582417168605 PEG10/HTRA1/CAV1/FBN1/CAV2/NREP/HSPA1A/TGFBR3/FERMT1 9 GO:0150105 protein localization to cell-cell junction 4/313 21/18722 0.00036633161106842 0.0134098504167065 ACTG1/DSP/LSR/ACTB 4 GO:0034599 cellular response to oxidative stress 14/313 288/18722 0.00037115604847358 0.0134570578717992 DHRS2/PAGE4/ANXA1/GPX1/FOS/JUN/PRDX1/SOD3/STK24/HSPA1A/HSPB1/PARP1/TPM1/RHOB 14 GO:0036294 cellular response to decreased oxygen levels 10/313 161/18722 0.000387888242018649 0.0138143640985905 MALAT1/STC2/ENO1/PMAIP1/BACH1/PGK1/TMBIM6/EGR1/DNMT3A/CCNB1 10 GO:0006163 purine nucleotide metabolic process 17/313 396/18722 0.00038826817928794 0.0138143640985905 GAPDH/LDHA/ALDOA/CROT/PKM/TPI1/ENO1/PGAM1/SLC26A2/INSR/PGK1/RHOA/TMSB4X/PDE4B/PARP1/MPC2/TECR 17 GO:1903522 regulation of blood circulation 13/313 256/18722 0.000395216613226554 0.013931385616236 CYP2J2/CAV1/GSTO1/ATP2B1/DSP/SRI/ISL1/RHOA/PDE4B/TPM1/CALM1/GJA1/RGS2 13 GO:2001234 negative regulation of apoptotic signaling pathway 12/313 224/18722 0.000407471076431421 0.0140076302644774 ENO1/GPX1/MIF/PTTG1IP/YBX3/SERPINE1/TMBIM1/HERPUD1/HSPA1A/HSPB1/TMBIM6/CLU 12 GO:0005996 monosaccharide metabolic process 13/313 257/18722 0.000410150920772091 0.0140076302644774 GAPDH/ALDOA/IGF2/TPI1/ENO1/PMAIP1/GSTO1/PHLDA2/INSR/PGK1/AKR1B1/PGP/SLC2A1 13 GO:0014032 neural crest cell development 7/313 81/18722 0.000412097344266212 0.0140076302644774 EFNB1/FN1/NRP2/PDCD6/SEMA6D/ISL1/HES1 7 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 7/313 81/18722 0.000412097344266212 0.0140076302644774 PEG10/HTRA1/CAV1/FBN1/CAV2/HSPA1A/TGFBR3 7 GO:0007565 female pregnancy 11/313 193/18722 0.000419363647654813 0.0141284726249723 STC2/FOS/RPL29/BSG/FOSB/FBLN1/PGF/AKR1B1/GJA1/SLC2A1/RGS2 11 GO:0034284 response to monosaccharide 12/313 225/18722 0.000424121650320061 0.0141634309014778 LDHA/KRT18/DYNLL1/SRI/SOX4/PHPT1/RHOA/MPC2/GJA1/HMGN3/TRA2B/EGR1 12 GO:0051098 regulation of binding 16/313 363/18722 0.000430214233123231 0.0142419616130447 CAV1/C4orf3/PHLDA2/JUN/SRI/ISL1/TMSB4X/S100A10/PARP1/TMBIM6/CALM1/ACTB/STMN1/TGFBR3/PLK2/HES1 16 GO:0051412 response to corticosterone 4/313 22/18722 0.000441878545325587 0.0143315065092445 FOS/ATP2B1/FOSB/CALM1 4 GO:0060563 neuroepithelial cell differentiation 4/313 22/18722 0.000441878545325587 0.0143315065092445 SERPINE1/SOX4/CEBPB/HES1 4 GO:1905897 regulation of response to endoplasmic reticulum stress 7/313 82/18722 0.000444212705040939 0.0143315065092445 CAV1/PMAIP1/HERPUD1/HSPA1A/TMBIM6/PPP1R15A/CLU 7 GO:0030073 insulin secretion 11/313 195/18722 0.000457511658610295 0.0146365284397428 DYNLL1/ANXA1/SRI/ISL1/SOX4/SLC16A1/PHPT1/MPC2/GJA1/HMGN3/FAM3B 11 GO:0001701 in utero embryonic development 16/313 367/18722 0.000484730512213261 0.0153780754999657 KRT19/KRT8/IGF2/STMN3/LY6E/MBD3/PHLDA2/YBX3/MYH9/PRMT1/CEBPB/ITGB1/YBX1/NMT1/CCNB1/HES1 16 GO:0010466 negative regulation of peptidase activity 13/313 262/18722 0.000492224122320873 0.0154867539973187 GAPDH/SERPINB9/TFPI2/TIMP2/ITIH5/GPX1/TIMP3/SERPINB1/SERPINE1/DHCR24/PTTG1/HERPUD1/BIRC5 13 GO:0045732 positive regulation of protein catabolic process 12/313 231/18722 0.000536569217563406 0.0167435984529827 CAV1/PTTG1IP/DDA1/OAZ1/EZR/CTSC/HERPUD1/HSPA1A/CDC20/GJA1/CLU/PLK2 12 GO:0045862 positive regulation of proteolysis 16/313 372/18722 0.00056113724204125 0.0173678819548865 CAV1/FN1/ENO1/PMAIP1/PDCD6/DDA1/FBLN1/MYH9/RHOA/CTSC/HERPUD1/HSPA1A/CDC20/CLU/PLK2/LGMN 16 GO:0031333 negative regulation of protein-containing complex assembly 9/313 140/18722 0.000587600248947421 0.0179234312943236 LMO4/PFN1/ISL1/TMSB4X/SCIN/JAM3/STMN1/CLU/KANK4 9 GO:0014031 mesenchymal cell development 7/313 86/18722 0.000593210492010711 0.0179234312943236 EFNB1/FN1/NRP2/PDCD6/SEMA6D/ISL1/HES1 7 GO:0048864 stem cell development 7/313 86/18722 0.000593210492010711 0.0179234312943236 EFNB1/FN1/NRP2/PDCD6/SEMA6D/ISL1/HES1 7 GO:0050708 regulation of protein secretion 13/313 268/18722 0.000608702728084159 0.0182467030379244 WLS/DYNLL1/ANXA1/SRI/ISL1/SOX4/SLC16A1/PHPT1/EZR/MPC2/GJA1/HMGN3/EXOC1 13 GO:0031639 plasminogen activation 4/313 24/18722 0.000625208048079025 0.0185950549924754 ENO1/SERPINE1/PGK1/DHCR24 4 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 6/313 63/18722 0.000635103384338368 0.0187040120272897 PMAIP1/CEBPB/HERPUD1/HSPA1A/TMBIM6/PPP1R15A 6 GO:0014912 negative regulation of smooth muscle cell migration 5/313 42/18722 0.000648042283993595 0.0187040120272897 IGFBP3/SERPINE1/SEMA6D/RHOA/TPM1 5 GO:0045214 sarcomere organization 5/313 42/18722 0.000648042283993595 0.0187040120272897 KRT19/KRT8/ACTG1/ITGB1/TPM1 5 GO:0048738 cardiac muscle tissue development 12/313 236/18722 0.000648523663672772 0.0187040120272897 LY6E/DSP/ISL1/PRMT1/ITGB1/FHL2/TPM1/GJA1/TGFBR3/ID2/CCNB1/RGS2 12 GO:0072521 purine-containing compound metabolic process 17/313 416/18722 0.000676573866364272 0.0189331598905766 GAPDH/LDHA/ALDOA/CROT/PKM/TPI1/ENO1/PGAM1/SLC26A2/INSR/PGK1/RHOA/TMSB4X/PDE4B/PARP1/MPC2/TECR 17 GO:0045765 regulation of angiogenesis 15/313 342/18722 0.000679539405973099 0.0189331598905766 PKM/ADAM12/PDCD6/SERPINE1/VEGFB/ISL1/PGF/PGK1/ITGB1/FLT1/HSPB1/ITGB8/ADAMTS1/RHOB/PLK2 15 GO:0006749 glutathione metabolic process 6/313 64/18722 0.000691105341518304 0.0189331598905766 CLIC3/GSTO1/GPX1/IDH1/GPX4/CLIC1 6 GO:0001765 membrane raft assembly 3/313 11/18722 0.000691281645597622 0.0189331598905766 CAV1/CAV2/S100A10 3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 3/313 11/18722 0.000691281645597622 0.0189331598905766 GSTO1/SRI/CALM1 3 GO:0106049 regulation of cellular response to osmotic stress 3/313 11/18722 0.000691281645597622 0.0189331598905766 EFHD1/YBX3/CLN3 3 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction 3/313 11/18722 0.000691281645597622 0.0189331598905766 CAV1/SRI/CALM1 3 GO:0046942 carboxylic acid transport 13/313 273/18722 0.000722801557425372 0.0191541610457204 SLC6A8/ANXA1/SLC7A5/SLC16A1/SLC26A2/SERINC5/ITGB1/SLC13A3/SLC43A2/MPC2/CLN3/GJA1/RGS2 13 GO:0120178 steroid hormone biosynthetic process 5/313 43/18722 0.000723394127344401 0.0191541610457204 CYP11A1/CYP19A1/HSD17B1/AKR1B1/EGR1 5 GO:0050678 regulation of epithelial cell proliferation 16/313 381/18722 0.000724838054815466 0.0191541610457204 HTRA1/IGF2/CAV1/NRP2/GPX1/PDCD6/CAV2/VEGFB/ISL1/PGF/MAGED1/FLT1/GJA1/ERRFI1/TGFBR3/HES1 16 GO:0031579 membrane raft organization 4/313 25/18722 0.00073456987461917 0.0191541610457204 CAV1/CAV2/S100A10/CLN3 4 GO:0086064 cell communication by electrical coupling involved in cardiac conduction 4/313 25/18722 0.00073456987461917 0.0191541610457204 CAV1/SRI/CALM1/GJA1 4 GO:1901798 positive regulation of signal transduction by p53 class mediator 4/313 25/18722 0.00073456987461917 0.0191541610457204 RPL23/DDX5/PMAIP1/EIF5A 4 GO:1903959 regulation of anion transmembrane transport 4/313 25/18722 0.00073456987461917 0.0191541610457204 TCAF1/ITGB1/SLC43A2/RGS2 4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 7/313 90/18722 0.000779416082741241 0.0201852858979313 CAV1/DDA1/HERPUD1/HSPA1A/CDC20/CLU/PLK2 7 GO:1903573 negative regulation of response to endoplasmic reticulum stress 5/313 44/18722 0.000805104446090531 0.0206724149584477 HERPUD1/HSPA1A/TMBIM6/PPP1R15A/CLU 5 GO:1901342 regulation of vasculature development 15/313 348/18722 0.000811119524475124 0.0206724149584477 PKM/ADAM12/PDCD6/SERPINE1/VEGFB/ISL1/PGF/PGK1/ITGB1/FLT1/HSPB1/ITGB8/ADAMTS1/RHOB/PLK2 15 GO:0042446 hormone biosynthetic process 6/313 66/18722 0.000814515955809602 0.0206724149584477 CYP11A1/STC2/CYP19A1/HSD17B1/AKR1B1/EGR1 6 GO:0009410 response to xenobiotic stimulus 18/313 462/18722 0.000823501753711808 0.0207620607707341 LDHA/CYP2J2/PLIN2/ANXA1/TIMP2/GSTO1/GPX1/FOS/JUN/ADIRF/FOSB/VEGFB/PGF/RHOA/S100A10/PDE4B/DNMT3A/CCNB1 18 GO:0014033 neural crest cell differentiation 7/313 91/18722 0.000832498595527381 0.0208508036392943 EFNB1/FN1/NRP2/PDCD6/SEMA6D/ISL1/HES1 7 GO:0022898 regulation of transmembrane transporter activity 13/313 278/18722 0.000854407568175896 0.0212596706669649 CAV1/FXYD3/C4orf3/GSTO1/TCAF1/SRI/ITGB1/TMSB4X/PDE4B/CALM1/ACTB/GJA1/AHNAK 13 GO:0006898 receptor-mediated endocytosis 12/313 244/18722 0.000868113576388816 0.0214509977914385 CAV1/CD63/CAV2/SERPINE1/AAK1/EZR/INSR/ITGB1/CLTB/CLN3/CLU/AP2A2 12 GO:0070527 platelet aggregation 6/313 67/18722 0.000882262967830993 0.0214509977914385 ACTG1/FN1/MYH9/CLIC1/HSPB1/ACTB 6 GO:0043542 endothelial cell migration 13/313 279/18722 0.000883007914630557 0.0214509977914385 NRP2/ANXA1/GPX1/PDCD6/MYH9/RHOA/ITGB1/TMSB4X/HSPB1/S100P/RHOB/PLK2/LGMN 13 GO:0045861 negative regulation of proteolysis 15/313 351/18722 0.000884635317377424 0.0214509977914385 GAPDH/SERPINB9/TFPI2/RPL23/TIMP2/ITIH5/GPX1/TIMP3/SERPINB1/SERPINE1/DHCR24/PTTG1/HERPUD1/BIRC5/CLN3 15 GO:0098656 anion transmembrane transport 12/313 245/18722 0.000899476715990098 0.0216728345428753 SLC6A8/SLC7A5/TCAF1/SLC16A1/SLC26A2/ITGB1/SLC13A4/SLC13A3/SLC43A2/MPC2/GJA1/RGS2 12 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress 3/313 12/18722 0.000910334437726569 0.0217793181753297 JUN/HSPA1A/TMBIM6 3 GO:0009749 response to glucose 11/313 212/18722 0.000915337774639548 0.0217793181753297 LDHA/DYNLL1/SRI/SOX4/PHPT1/RHOA/MPC2/GJA1/HMGN3/TRA2B/EGR1 11 GO:0042176 regulation of protein catabolic process 16/313 391/18722 0.000952952439908564 0.0225334778803224 CAV1/RPL23/TIMP2/GPX1/TIMP3/PTTG1IP/DDA1/OAZ1/EZR/CTSC/HERPUD1/HSPA1A/CDC20/GJA1/CLU/PLK2 16 GO:0055010 ventricular cardiac muscle tissue morphogenesis 5/313 46/18722 0.000988927173117511 0.0232397885682615 LY6E/DSP/ISL1/TPM1/TGFBR3 5 GO:0052548 regulation of endopeptidase activity 17/313 432/18722 0.00102440452355144 0.0239258160807382 GAPDH/SERPINB9/TFPI2/PMAIP1/TIMP2/ITIH5/GPX1/TIMP3/PDCD6/SERPINB1/SERPINE1/DHCR24/RHOA/PTTG1/HERPUD1/BIRC5/LGMN 17 GO:0010631 epithelial cell migration 15/313 357/18722 0.0010487108887301 0.0243441606914359 NRP2/ANXA1/GPX1/PFN1/PDCD6/MYH9/RHOA/ITGB1/TMSB4X/HSPB1/S100P/RHOB/PLK2/FERMT1/LGMN 15 GO:0003231 cardiac ventricle development 8/313 123/18722 0.00109008457433507 0.0251512240878401 LY6E/DSP/LMO4/ISL1/SOX4/TPM1/TGFBR3/HES1 8 GO:0007596 blood coagulation 11/313 217/18722 0.00110614832747645 0.0252770938671694 CAV1/TFPI2/ACTG1/F5/FN1/SERPINE1/FBLN1/MYH9/CLIC1/HSPB1/ACTB 11 GO:1901653 cellular response to peptide 15/313 359/18722 0.00110881919511881 0.0252770938671694 IGF2/PKM/CAV1/RPL23/CYP11A1/FBN1/ATP2B1/CAV2/INSR/AKR1B1/PTPRA/PARP1/GJA1/ERRFI1/LGMN 15 GO:0090132 epithelium migration 15/313 360/18722 0.00113994737848093 0.0254273334733547 NRP2/ANXA1/GPX1/PFN1/PDCD6/MYH9/RHOA/ITGB1/TMSB4X/HSPB1/S100P/RHOB/PLK2/FERMT1/LGMN 15 GO:0044264 cellular polysaccharide metabolic process 7/313 96/18722 0.0011422226961108 0.0254273334733547 IGF2/PYGL/PHLDA2/UGP2/INSR/AGL/B3GNT2 7 GO:0007163 establishment or maintenance of cell polarity 11/313 218/18722 0.00114799202378684 0.0254273334733547 CLIC4/MYH9/RHOA/ITGB1/DST/ACTB/GJA1/JAM3/RHOB/FERMT1/HES1 11 GO:0008360 regulation of cell shape 9/313 154/18722 0.00115940203152436 0.0254273334733547 ALDOA/FN1/ANXA1/EZR/MYH9/RHOA/TPM1/EPB41L3/RHOB 9 GO:0010958 regulation of amino acid import across plasma membrane 3/313 13/18722 0.00116884248958158 0.0254273334733547 ITGB1/SLC43A2/RGS2 3 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 3/313 13/18722 0.00116884248958158 0.0254273334733547 GSTO1/SRI/CALM1 3 GO:0060347 heart trabecula formation 3/313 13/18722 0.00116884248958158 0.0254273334733547 FHL2/TGFBR3/ADAMTS1 3 GO:1903789 regulation of amino acid transmembrane transport 3/313 13/18722 0.00116884248958158 0.0254273334733547 ITGB1/SLC43A2/RGS2 3 GO:0009743 response to carbohydrate 12/313 253/18722 0.00118606845070739 0.0256143118680833 LDHA/KRT18/DYNLL1/SRI/SOX4/PHPT1/RHOA/MPC2/GJA1/HMGN3/TRA2B/EGR1 12 GO:0097191 extrinsic apoptotic signaling pathway 11/313 219/18722 0.00119113168104719 0.0256143118680833 KRT8/CAV1/KRT18/PMAIP1/GPX1/TIMP3/TNFRSF1A/SERPINE1/TMBIM1/HSPA1A/TNFRSF12A 11 GO:0003208 cardiac ventricle morphogenesis 6/313 71/18722 0.00119762214670839 0.0256143118680833 LY6E/DSP/ISL1/SOX4/TPM1/TGFBR3 6 GO:0044706 multi-multicellular organism process 11/313 220/18722 0.00123559763561585 0.0262788837921204 STC2/FOS/RPL29/BSG/FOSB/FBLN1/PGF/AKR1B1/GJA1/SLC2A1/RGS2 11 GO:0044403 biological process involved in symbiotic interaction 13/313 290/18722 0.00125433157995881 0.0263442802949215 GAPDH/SERPINB9/CAV1/FN1/LY6E/GPX1/JUN/BSG/CAV2/CFL1/INSR/ITGB1/HSPA1A 13 GO:0051924 regulation of calcium ion transport 12/313 255/18722 0.0012684720280567 0.0263442802949215 CAV1/C4orf3/GSTO1/ATP2B1/SRI/RHOA/PDE4B/TMBIM6/SARAF/CALM1/GJA1/AHNAK 12 GO:1903362 regulation of cellular protein catabolic process 12/313 255/18722 0.0012684720280567 0.0263442802949215 CAV1/RPL23/GPX1/PTTG1IP/DDA1/EZR/CTSC/HERPUD1/HSPA1A/CDC20/CLU/PLK2 12 GO:0005977 glycogen metabolic process 6/313 72/18722 0.00128846135274495 0.0263442802949215 IGF2/PYGL/PHLDA2/UGP2/INSR/AGL 6 GO:0030330 DNA damage response, signal transduction by p53 class mediator 6/313 72/18722 0.00128846135274495 0.0263442802949215 DDX5/PMAIP1/MIF/PTTG1IP/SOX4/PLK2 6 GO:0033627 cell adhesion mediated by integrin 6/313 72/18722 0.00128846135274495 0.0263442802949215 FBN1/SERPINE1/ITGB1/ITGB8/JAM3/FERMT1 6 GO:0061337 cardiac conduction 7/313 98/18722 0.00128880949368873 0.0263442802949215 CAV1/ATP2B1/DSP/SRI/ISL1/CALM1/GJA1 7 GO:0090130 tissue migration 15/313 365/18722 0.00130687165788578 0.0263442802949215 NRP2/ANXA1/GPX1/PFN1/PDCD6/MYH9/RHOA/ITGB1/TMSB4X/HSPB1/S100P/RHOB/PLK2/FERMT1/LGMN 15 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 12/313 256/18722 0.00131141901567129 0.0263442802949215 PEG10/HTRA1/CAV1/FBN1/CAV2/NREP/FKBP8/HSPA1A/PARP1/TGFBR3/FERMT1/HES1 12 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 5/313 49/18722 0.00132076529701315 0.0263442802949215 PMAIP1/GPX1/TIMP3/SERPINE1/TMBIM1 5 GO:0000302 response to reactive oxygen species 11/313 222/18722 0.00132863194552795 0.0263442802949215 LDHA/ANXA1/GPX1/FOS/JUN/PRDX1/SOD3/STK24/TPM1/TRA2B/RHOB 11 GO:0007599 hemostasis 11/313 222/18722 0.00132863194552795 0.0263442802949215 CAV1/TFPI2/ACTG1/F5/FN1/SERPINE1/FBLN1/MYH9/CLIC1/HSPB1/ACTB 11 GO:0050817 coagulation 11/313 222/18722 0.00132863194552795 0.0263442802949215 CAV1/TFPI2/ACTG1/F5/FN1/SERPINE1/FBLN1/MYH9/CLIC1/HSPB1/ACTB 11 GO:0140694 non-membrane-bounded organelle assembly 15/313 367/18722 0.00137916830063236 0.0270291669745828 KRT19/KRT8/RPS27/NEK6/ACTG1/RPL38/RPS28/CCSAP/EZR/RHOA/ITGB1/HSPA1A/TPM1/CDC20/PLK2 15 GO:0006073 cellular glucan metabolic process 6/313 73/18722 0.00138447269767366 0.0270291669745828 IGF2/PYGL/PHLDA2/UGP2/INSR/AGL 6 GO:0044042 glucan metabolic process 6/313 73/18722 0.00138447269767366 0.0270291669745828 IGF2/PYGL/PHLDA2/UGP2/INSR/AGL 6 GO:0010959 regulation of metal ion transport 16/313 406/18722 0.00140797280756557 0.0273477167265415 CAV1/FXYD3/C4orf3/CD63/GSTO1/ATP2B1/SRI/RHOA/ITGB1/PDE4B/TMBIM6/SARAF/CALM1/GJA1/PRSS8/AHNAK 16 GO:0071692 protein localization to extracellular region 15/313 368/18722 0.00141655851042803 0.0273748134477132 WLS/FBN1/DYNLL1/ANXA1/SRI/ISL1/SOX4/SLC16A1/PHPT1/EZR/MPC2/GJA1/HMGN3/FAM3B/EXOC1 15 GO:0071214 cellular response to abiotic stimulus 14/313 331/18722 0.00143484853201669 0.0274495897557162 EFHD1/ADIRF/YBX3/TNFRSF1A/AKR1B1/PARP1/CLN3/GJA1/TMEM150C/NMT1/ERRFI1/EGR1/RHOB/SLC2A1 14 GO:0104004 cellular response to environmental stimulus 14/313 331/18722 0.00143484853201669 0.0274495897557162 EFHD1/ADIRF/YBX3/TNFRSF1A/AKR1B1/PARP1/CLN3/GJA1/TMEM150C/NMT1/ERRFI1/EGR1/RHOB/SLC2A1 14 GO:0050900 leukocyte migration 15/313 369/18722 0.00145479634388573 0.0276910219890529 ANXA1/MIF/CD99/BSG/SERPINE1/VEGFB/CSF3R/PGF/MYH9/RHOA/ITGB1/PDE4B/FLT1/JAM3/LGMN 15 GO:0047484 regulation of response to osmotic stress 3/313 14/18722 0.00146928984549217 0.0276910219890529 EFHD1/YBX3/CLN3 3 GO:0086103 G protein-coupled receptor signaling pathway involved in heart process 3/313 14/18722 0.00146928984549217 0.0276910219890529 CAV1/PDE4B/RGS2 3 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 6/313 74/18722 0.00148584694457683 0.0278651197931231 LBH/DDX5/ISL1/UBA5/RHOA/PARP1 6 GO:0098869 cellular oxidant detoxification 7/313 101/18722 0.00153583442098272 0.0286613805915746 GPX3/GSTO1/GPX1/PRDX1/GPX4/SOD3/PRDX6 7 GO:0010038 response to metal ion 15/313 373/18722 0.00161652630544892 0.029902158577782 CAV1/HSD17B1/FOS/JUN/PDCD6/FUS/BSG/FOSB/SOD3/CLIC4/PARP1/CALM1/DNMT3A/LGMN/CCNB1 15 GO:1901654 response to ketone 10/313 194/18722 0.00162571354474601 0.029902158577782 CAV1/FOS/ATP2B1/FOSB/AKR1B1/PARP1/CALM1/ERRFI1/TGFBR3/NR3C1 10 GO:1904063 negative regulation of cation transmembrane transport 7/313 102/18722 0.00162588569099051 0.029902158577782 CAV1/C4orf3/GSTO1/SRI/SLC43A2/CALM1/RGS2 7 GO:0003018 vascular process in circulatory system 12/313 263/18722 0.00164700175957473 0.0301448831668316 CAV1/GPX1/SLC7A5/ATP2B1/SOD3/SLC16A1/INSR/RHOA/SLC13A3/GJA1/SLC2A1/RGS2 12 GO:0071711 basement membrane organization 4/313 31/18722 0.00168874714068161 0.0307610543759564 CAV1/CAV2/ITGB1/FERMT1 4 GO:0015833 peptide transport 12/313 264/18722 0.00170025209774064 0.0308231416004695 DYNLL1/ANXA1/SRI/ISL1/SOX4/SLC16A1/PHPT1/SLC13A3/MPC2/GJA1/HMGN3/FAM3B 12 GO:0003279 cardiac septum development 7/313 103/18722 0.00171999277444138 0.0308868513787657 NRP2/LMO4/ADAMTS6/ISL1/SOX4/TGFBR3/HES1 7 GO:0090277 positive regulation of peptide hormone secretion 7/313 103/18722 0.00171999277444138 0.0308868513787657 DYNLL1/SRI/ISL1/SOX4/PHPT1/MPC2/GJA1 7 GO:0030595 leukocyte chemotaxis 11/313 230/18722 0.00176018643267576 0.031390505232233 ANXA1/MIF/BSG/SERPINE1/VEGFB/CSF3R/PGF/PDE4B/FLT1/JAM3/LGMN 11 GO:0007568 aging 14/313 339/18722 0.00179238258534131 0.031390505232233 NEK6/TIMP2/MBD3/MIF/FOS/ATP2B1/JUN/GPX4/SERPINE1/CTSC/YBX1/PLK2/ID2/DNMT3A 14 GO:0010595 positive regulation of endothelial cell migration 8/313 133/18722 0.00179749533032979 0.031390505232233 NRP2/ANXA1/PDCD6/TMSB4X/HSPB1/RHOB/PLK2/LGMN 8 GO:0046887 positive regulation of hormone secretion 8/313 133/18722 0.00179749533032979 0.031390505232233 DYNLL1/CYP19A1/SRI/ISL1/SOX4/PHPT1/MPC2/GJA1 8 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 8/313 133/18722 0.00179749533032979 0.031390505232233 CAV1/DDA1/CTSC/HERPUD1/HSPA1A/CDC20/CLU/PLK2 8 GO:0051284 positive regulation of sequestering of calcium ion 3/313 15/18722 0.00181400345445003 0.031390505232233 GSTO1/SRI/CALM1 3 GO:1901841 regulation of high voltage-gated calcium channel activity 3/313 15/18722 0.00181400345445003 0.031390505232233 SRI/PDE4B/CALM1 3 GO:2001028 positive regulation of endothelial cell chemotaxis 3/313 15/18722 0.00181400345445003 0.031390505232233 TMSB4X/HSPB1/LGMN 3 GO:0031016 pancreas development 6/313 77/18722 0.00182409076177792 0.0314222331678215 IGF2/WLS/ANXA1/ISL1/SOX4/HES1 6 GO:0050796 regulation of insulin secretion 9/313 165/18722 0.00187054866521108 0.031565384407026 DYNLL1/SRI/ISL1/SOX4/SLC16A1/PHPT1/MPC2/GJA1/HMGN3 9 GO:0007566 embryo implantation 5/313 53/18722 0.0018826316901076 0.031565384407026 STC2/RPL29/BSG/FBLN1/GJA1 5 GO:0061041 regulation of wound healing 8/313 134/18722 0.00188451217369541 0.031565384407026 CAV1/ACTG1/ANXA1/SERPINE1/ITGB1/TNFRSF12A/GJA1/FERMT1 8 GO:0050878 regulation of body fluid levels 15/313 379/18722 0.00188717764784258 0.031565384407026 CAV1/TFPI2/ACTG1/F5/FN1/SERPINE1/FBLN1/MYH9/CLIC1/AKR1B1/HSPB1/LSR/ACTB/GJA1/STMN1 15 GO:0031099 regeneration 10/313 198/18722 0.00189031484613664 0.031565384407026 ANXA1/GPX1/ISL1/PGF/NREP/CEBPB/STK24/JAM3/TGFBR3/CCNB1 10 GO:0010644 cell communication by electrical coupling 4/313 32/18722 0.00190487697144257 0.031565384407026 CAV1/SRI/CALM1/GJA1 4 GO:0042744 hydrogen peroxide catabolic process 4/313 32/18722 0.00190487697144257 0.031565384407026 GPX3/GPX1/PRDX1/PRDX6 4 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 4/313 32/18722 0.00190487697144257 0.031565384407026 PMAIP1/HERPUD1/HSPA1A/TMBIM6 4 GO:0090287 regulation of cellular response to growth factor stimulus 13/313 304/18722 0.00190702348663409 0.031565384407026 PEG10/HTRA1/CAV1/FBN1/CD63/PDCD6/CAV2/NREP/FKBP8/HSPA1A/TGFBR3/FERMT1/HES1 13 GO:0007160 cell-matrix adhesion 11/313 233/18722 0.00194893670715101 0.0321194893685018 PLEKHA2/ACTG1/FN1/CD63/SERPINE1/RHOA/ITGB1/S100A10/PTPRA/JAM3/FERMT1 11 GO:0030099 myeloid cell differentiation 15/313 381/18722 0.00198539512442013 0.0324499118111626 DHRS2/FBN1/FOS/JUN/CSF3R/MYH9/PRMT1/UBA5/CEBPB/SCIN/HSPA1A/PARP1/ITGB8/TGFBR3/ID2 15 GO:0034329 cell junction assembly 16/313 420/18722 0.00198603347832962 0.0324499118111626 CAV1/ACTG1/FN1/RAB17/PKP3/RHOA/S100A10/DST/PTPRA/LSR/CTNND1/ACTB/GJA1/JAM3/EPB41L3/CLDN7 16 GO:0009914 hormone transport 13/313 306/18722 0.00201981449976819 0.0327631019499938 DYNLL1/ANXA1/CYP19A1/SLC7A5/SRI/ISL1/SOX4/SLC16A1/PHPT1/MPC2/GJA1/HMGN3/FAM3B 13 GO:0002793 positive regulation of peptide secretion 7/313 106/18722 0.00202788580164779 0.0327631019499938 DYNLL1/SRI/ISL1/SOX4/PHPT1/MPC2/GJA1 7 GO:1903034 regulation of response to wounding 9/313 167/18722 0.00203101971636421 0.0327631019499938 CAV1/ACTG1/ANXA1/SERPINE1/STK24/ITGB1/TNFRSF12A/GJA1/FERMT1 9 GO:0030520 intracellular estrogen receptor signaling pathway 5/313 54/18722 0.00204680592746533 0.0328784395183988 LBH/DDX5/ISL1/UBA5/PARP1 5 GO:0005976 polysaccharide metabolic process 7/313 107/18722 0.0021394603847847 0.0340791869660056 IGF2/PYGL/PHLDA2/UGP2/INSR/AGL/B3GNT2 7 GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 7/313 107/18722 0.0021394603847847 0.0340791869660056 CAV1/DDA1/HERPUD1/HSPA1A/CDC20/CLU/PLK2 7 GO:0030072 peptide hormone secretion 11/313 236/18722 0.00215385492238909 0.0341655237063969 DYNLL1/ANXA1/SRI/ISL1/SOX4/SLC16A1/PHPT1/MPC2/GJA1/HMGN3/FAM3B 11 GO:0048872 homeostasis of number of cells 12/313 272/18722 0.00217937890694446 0.0341697637471138 RPS17/ANXA1/PMAIP1/PRDX1/SOX4/PRMT1/UBA5/PDE4B/HSPA1A/JAM3/TGFBR3/ID2 12 GO:0016051 carbohydrate biosynthetic process 10/313 202/18722 0.00218867781879009 0.0341697637471138 IGF2/TPI1/UGP2/INSR/PGK1/AGL/AKR1B1/ISYNA1/PGP/B3GNT2 10 GO:0051014 actin filament severing 3/313 16/18722 0.00220515873552526 0.0341697637471138 CFL1/MYH9/SCIN 3 GO:0051238 sequestering of metal ion 3/313 16/18722 0.00220515873552526 0.0341697637471138 FTL/FTH1/SRI 3 GO:0097284 hepatocyte apoptotic process 3/313 16/18722 0.00220515873552526 0.0341697637471138 KRT8/KRT18/DNMT3A 3 GO:0001755 neural crest cell migration 5/313 55/18722 0.00222118872785739 0.0341697637471138 EFNB1/FN1/NRP2/SEMA6D/ISL1 5 GO:0061614 pri-miRNA transcription by RNA polymerase II 5/313 55/18722 0.00222118872785739 0.0341697637471138 DDX5/FOS/JUN/EGR1/NR3C1 5 GO:0019318 hexose metabolic process 11/313 237/18722 0.00222592629610828 0.0341697637471138 GAPDH/ALDOA/IGF2/TPI1/ENO1/PMAIP1/PHLDA2/INSR/PGK1/AKR1B1/PGP 11 GO:0032409 regulation of transporter activity 13/313 310/18722 0.00226193368638807 0.0344447261763176 CAV1/FXYD3/C4orf3/GSTO1/TCAF1/SRI/ITGB1/TMSB4X/PDE4B/CALM1/ACTB/GJA1/AHNAK 13 GO:0060326 cell chemotaxis 13/313 310/18722 0.00226193368638807 0.0344447261763176 ANXA1/MIF/BSG/SERPINE1/VEGFB/CSF3R/PGF/TMSB4X/PDE4B/FLT1/HSPB1/JAM3/LGMN 13 GO:0043254 regulation of protein-containing complex assembly 16/313 427/18722 0.00234247094724347 0.0355238999186512 LMO4/COTL1/PFN1/ICE1/ISL1/RHOA/TMSB4X/SCIN/HSPA1A/PARP1/JAM3/STMN1/IQGAP2/CLU/KANK4/FERMT1 16 GO:0071383 cellular response to steroid hormone stimulus 10/313 204/18722 0.00235146382440244 0.0355238999186512 LBH/DDX5/ANXA1/ATP2B1/ISL1/UBA5/RHOA/PARP1/ERRFI1/NR3C1 10 GO:0034766 negative regulation of ion transmembrane transport 7/313 109/18722 0.00237679497929153 0.0357284136335276 CAV1/C4orf3/GSTO1/SRI/SLC43A2/CALM1/RGS2 7 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 4/313 34/18722 0.00239315615354598 0.0357284136335276 DDX5/PMAIP1/MIF/PTTG1IP 4 GO:0086004 regulation of cardiac muscle cell contraction 4/313 34/18722 0.00239315615354598 0.0357284136335276 CAV1/DSP/SRI/PDE4B 4 GO:0071385 cellular response to glucocorticoid stimulus 5/313 56/18722 0.00240614567797685 0.0357820179533511 ANXA1/ATP2B1/ISL1/ERRFI1/NR3C1 5 GO:0014812 muscle cell migration 7/313 110/18722 0.00250281632598268 0.0369463178013636 IGFBP3/ANXA1/SERPINE1/SEMA6D/RHOA/TPM1/ADAMTS1 7 GO:0001892 embryonic placenta development 6/313 82/18722 0.00251355301038959 0.0369463178013636 KRT19/KRT8/IGF2/PHLDA2/CEBPB/HES1 6 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 6/313 82/18722 0.00251355301038959 0.0369463178013636 PMAIP1/GPX1/TIMP3/TNFRSF1A/SERPINE1/TMBIM1 6 GO:0002790 peptide secretion 11/313 242/18722 0.00261624108059431 0.0381610336928066 DYNLL1/ANXA1/SRI/ISL1/SOX4/SLC16A1/PHPT1/MPC2/GJA1/HMGN3/FAM3B 11 GO:1903320 regulation of protein modification by small protein conjugation or removal 11/313 242/18722 0.00261624108059431 0.0381610336928066 CAV1/RPL23/PDCD6/PTTG1IP/SOX4/HERPUD1/HMG20B/HSPA1A/CDC20/ARRDC3/EGR1 11 GO:0001780 neutrophil homeostasis 3/313 17/18722 0.00264478498535555 0.0382840168792721 ANXA1/PDE4B/JAM3 3 GO:0060644 mammary gland epithelial cell differentiation 3/313 17/18722 0.00264478498535555 0.0382840168792721 LBH/CEBPB/ID2 3 GO:0033146 regulation of intracellular estrogen receptor signaling pathway 4/313 35/18722 0.00266684363380236 0.0384570974010818 LBH/ISL1/UBA5/PARP1 4 GO:0086065 cell communication involved in cardiac conduction 5/313 58/18722 0.00280924933769151 0.0403161680135837 CAV1/DSP/SRI/CALM1/GJA1 5 GO:0034763 negative regulation of transmembrane transport 8/313 143/18722 0.00282622963320571 0.0403161680135837 CAV1/C4orf3/GSTO1/SRI/OAZ1/SLC43A2/CALM1/RGS2 8 GO:0006112 energy reserve metabolic process 6/313 84/18722 0.00283812267602848 0.0403161680135837 IGF2/PYGL/PHLDA2/UGP2/INSR/AGL 6 GO:0006970 response to osmotic stress 6/313 84/18722 0.00283812267602848 0.0403161680135837 EFHD1/YBX3/AKR1B1/CLN3/ERRFI1/SLC2A1 6 GO:0032956 regulation of actin cytoskeleton organization 14/313 357/18722 0.0028729616213119 0.0406593490421353 ACTG1/COTL1/PFN1/PHPT1/RHOA/TMSB4X/SCIN/S100A10/TPM1/JAM3/STMN1/IQGAP2/RHOB/KANK4 14 GO:0010634 positive regulation of epithelial cell migration 9/313 176/18722 0.00289424352067743 0.0408088336415518 NRP2/ANXA1/PFN1/PDCD6/TMSB4X/HSPB1/RHOB/PLK2/LGMN 9 GO:0008207 C21-steroid hormone metabolic process 4/313 36/18722 0.00296123946701081 0.0413723519281897 DHRS2/CYP11A1/AKR1B1/EGR1 4 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 4/313 36/18722 0.00296123946701081 0.0413723519281897 DYNLL1/SRI/PHPT1/MPC2 4 GO:0003007 heart morphogenesis 11/313 246/18722 0.00296681168279375 0.0413723519281897 NRP2/LY6E/DSP/ISL1/SOX4/INSR/FHL2/TPM1/TGFBR3/ADAMTS1/HES1 11 GO:0030100 regulation of endocytosis 10/313 211/18722 0.00299938885521495 0.0416176726833567 CAV1/CD63/RAB17/SERPINE1/AAK1/INSR/CD151/CALM1/CLN3/CLU 10 GO:0009306 protein secretion 14/313 359/18722 0.0030205477271546 0.0416176726833567 WLS/DYNLL1/ANXA1/SRI/ISL1/SOX4/SLC16A1/PHPT1/EZR/MPC2/GJA1/HMGN3/FAM3B/EXOC1 14 GO:0048010 vascular endothelial growth factor receptor signaling pathway 5/313 59/18722 0.00302813116188332 0.0416176726833567 PDCD6/VEGFB/PGF/FLT1/HSPB1 5 GO:0090303 positive regulation of wound healing 5/313 59/18722 0.00302813116188332 0.0416176726833567 ACTG1/ANXA1/SERPINE1/ITGB1/FERMT1 5 GO:1901800 positive regulation of proteasomal protein catabolic process 7/313 114/18722 0.00305903472019254 0.0418911697114137 CAV1/DDA1/HERPUD1/HSPA1A/CDC20/CLU/PLK2 7 GO:0035592 establishment of protein localization to extracellular region 14/313 360/18722 0.00309664138288128 0.0422541711277026 WLS/DYNLL1/ANXA1/SRI/ISL1/SOX4/SLC16A1/PHPT1/EZR/MPC2/GJA1/HMGN3/FAM3B/EXOC1 14 GO:0070997 neuron death 14/313 361/18722 0.00317430030779744 0.0431591473992316 GAPDH/GPX1/FOS/JUN/ISL1/DHCR24/RHOA/CEBPB/PARP1/BTG2/CLN3/EGR1/CLU/LGMN 14 GO:0051651 maintenance of location in cell 10/313 213/18722 0.00320854088951938 0.0433819190102563 CAV1/FTL/GSTO1/FTH1/SRI/TMSB4X/SCIN/CALM1/GJA1/MCOLN3 10 GO:0007015 actin filament organization 16/313 441/18722 0.00321637563640666 0.0433819190102563 ALDOA/ACTG1/COTL1/PFN1/CFL1/EZR/RHOA/TMSB4X/SCIN/S100A10/TPM4/TPM1/STMN1/IQGAP2/RHOB/KANK4 16 GO:0001936 regulation of endothelial cell proliferation 9/313 179/18722 0.00323885409289678 0.0433819190102563 IGF2/CAV1/NRP2/PDCD6/CAV2/VEGFB/PGF/FLT1/GJA1 9 GO:0046883 regulation of hormone secretion 11/313 249/18722 0.00325380423176432 0.0433819190102563 DYNLL1/ANXA1/CYP19A1/SRI/ISL1/SOX4/SLC16A1/PHPT1/MPC2/GJA1/HMGN3 11 GO:0031638 zymogen activation 5/313 60/18722 0.00325905669475526 0.0433819190102563 ENO1/SERPINE1/PGK1/DHCR24/LGMN 5 GO:0055008 cardiac muscle tissue morphogenesis 5/313 60/18722 0.00325905669475526 0.0433819190102563 LY6E/DSP/ISL1/TPM1/TGFBR3 5 GO:0030518 intracellular steroid hormone receptor signaling pathway 7/313 116/18722 0.00337032277238608 0.0443972968666914 LBH/DDX5/ISL1/UBA5/RHOA/PARP1/NR3C1 7 GO:0033559 unsaturated fatty acid metabolic process 7/313 116/18722 0.00337032277238608 0.0443972968666914 CYP2J2/ANXA1/GPX1/MIF/TNFRSF1A/GPX4/AKR1B1 7 GO:1990748 cellular detoxification 7/313 116/18722 0.00337032277238608 0.0443972968666914 GPX3/GSTO1/GPX1/PRDX1/GPX4/SOD3/PRDX6 7 GO:1903578 regulation of ATP metabolic process 6/313 87/18722 0.00338249616728054 0.0444040100304725 ENO1/PGAM1/INSR/RHOA/TMSB4X/PARP1 6 GO:0051235 maintenance of location 13/313 326/18722 0.00348113854243244 0.0455419052613069 CAV1/PLIN2/FBN1/FTL/GSTO1/FTH1/MEST/SRI/TMSB4X/SCIN/CALM1/GJA1/MCOLN3 13 GO:0071384 cellular response to corticosteroid stimulus 5/313 61/18722 0.00350239345415548 0.0456630543834585 ANXA1/ATP2B1/ISL1/ERRFI1/NR3C1 5 GO:0009612 response to mechanical stimulus 10/313 216/18722 0.00354388681428728 0.0460463382320534 FOS/JUN/TNFRSF1A/FOSB/RHOA/BTG2/GJA1/TMEM150C/SLC2A1/CCNB1 10 GO:0010232 vascular transport 6/313 88/18722 0.00358014571582932 0.0463592338100755 SLC7A5/SLC16A1/INSR/SLC13A3/GJA1/SLC2A1 6 GO:0051592 response to calcium ion 8/313 149/18722 0.00363444162136879 0.0467443217991587 CAV1/FOS/PDCD6/FUS/FOSB/CLIC4/CALM1/LGMN 8 GO:1905039 carboxylic acid transmembrane transport 8/313 149/18722 0.00363444162136879 0.0467443217991587 SLC7A5/SLC16A1/ITGB1/SLC13A3/SLC43A2/MPC2/SLC2A1/RGS2 8 GO:0000028 ribosomal small subunit assembly 3/313 19/18722 0.00367686833674579 0.0471307668619233 RPS27/RPL38/RPS28 3 GO:0051101 regulation of DNA binding 7/313 118/18722 0.00370520128177758 0.047334568052776 JUN/SRI/ISL1/TMSB4X/PARP1/CALM1/HES1 7 GO:0009117 nucleotide metabolic process 17/313 489/18722 0.00373639825028857 0.0475717866591352 GAPDH/LDHA/ALDOA/CROT/PKM/TPI1/ENO1/PGAM1/SLC26A2/INSR/PGK1/RHOA/TMSB4X/PDE4B/PARP1/MPC2/TECR 17 GO:0060135 maternal process involved in female pregnancy 5/313 62/18722 0.00375850835770382 0.0475717866591352 STC2/BSG/AKR1B1/GJA1/RGS2 5 GO:1903825 organic acid transmembrane transport 8/313 150/18722 0.00378494087249854 0.0475717866591352 SLC7A5/SLC16A1/ITGB1/SLC13A3/SLC43A2/MPC2/SLC2A1/RGS2 8 GO:0014910 regulation of smooth muscle cell migration 6/313 89/18722 0.00378624937160966 0.0475717866591352 IGFBP3/SERPINE1/SEMA6D/RHOA/TPM1/ADAMTS1 6 GO:0051781 positive regulation of cell division 6/313 89/18722 0.00378624937160966 0.0475717866591352 IGF2/LBH/VEGFB/PGF/RHOA/YBX1 6 GO:0034765 regulation of ion transmembrane transport 17/313 491/18722 0.0038918177106227 0.0487373356063836 CAV1/FXYD3/CLIC3/C4orf3/CD63/GSTO1/TCAF1/SRI/CLIC4/CLIC1/ITGB1/TMSB4X/PDE4B/SLC43A2/CALM1/AHNAK/RGS2 17 GO:2001236 regulation of extrinsic apoptotic signaling pathway 8/313 151/18722 0.00394021464844296 0.0491816300544994 CAV1/PMAIP1/GPX1/TIMP3/SERPINE1/TMBIM1/HSPA1A/TNFRSF12A 8 GO:1903115 regulation of actin filament-based movement 4/313 39/18722 0.00397605846599254 0.0494668450327895 CAV1/DSP/SRI/PDE4B 4 GO:0030901 midbrain development 6/313 90/18722 0.0040010231779574 0.0496152939364294 WLS/DYNLL1/RHOA/CALM1/ACTB/HES1 6 GO:0030239 myofibril assembly 5/313 63/18722 0.00402776740713188 0.0497847744121788 KRT19/KRT8/ACTG1/ITGB1/TPM1 5 GO:0010810 regulation of cell-substrate adhesion 10/313 221/18722 0.00416411391376571 0.0511380053861486 PLEKHA2/ACTG1/FN1/CCDC80/SERPINE1/FBLN1/RHOA/S100A10/PTPRA/FERMT1 10 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 10/313 221/18722 0.00416411391376571 0.0511380053861486 CAV1/RPL23/GPX1/DDA1/CTSC/HERPUD1/HSPA1A/CDC20/CLU/PLK2 10 GO:0046879 hormone secretion 12/313 295/18722 0.00420057618806427 0.0512819005845905 DYNLL1/ANXA1/CYP19A1/SRI/ISL1/SOX4/SLC16A1/PHPT1/MPC2/GJA1/HMGN3/FAM3B 12 GO:0051492 regulation of stress fiber assembly 6/313 91/18722 0.00422468373671717 0.0512819005845905 ACTG1/PFN1/RHOA/S100A10/TPM1/STMN1 6 GO:0042593 glucose homeostasis 11/313 258/18722 0.0042508491654179 0.0512819005845905 DYNLL1/PYGL/SRI/SOX4/SLC16A1/PHPT1/INSR/MPC2/HMGN3/TRA2B/FAM3B 11 GO:0120254 olefinic compound metabolic process 8/313 153/18722 0.00426548403562423 0.0512819005845905 CYP2J2/RDH13/CYP11A1/GPX1/HSD17B1/GPX4/AKR1B1/EGR1 8 GO:0062012 regulation of small molecule metabolic process 13/313 334/18722 0.00426594664575356 0.0512819005845905 IGF2/CAV1/ANXA1/ENO1/PMAIP1/PHLDA2/PGAM1/INSR/TMSB4X/PARP1/CLN3/PGP/EGR1 13 GO:0006700 C21-steroid hormone biosynthetic process 3/313 20/18722 0.00427269995450598 0.0512819005845905 CYP11A1/AKR1B1/EGR1 3 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 3/313 20/18722 0.00427269995450598 0.0512819005845905 HERPUD1/HSPA1A/TMBIM6 3 GO:0045995 regulation of embryonic development 5/313 64/18722 0.00431053537879405 0.0512819005845905 PHLDA2/CCSAP/CFL1/INSR/HES1 5 GO:0055002 striated muscle cell development 5/313 64/18722 0.00431053537879405 0.0512819005845905 KRT19/KRT8/ACTG1/ITGB1/TPM1 5 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 5/313 64/18722 0.00431053537879405 0.0512819005845905 DYNLL1/SRI/PHPT1/MPC2/HMGN3 5 GO:0044275 cellular carbohydrate catabolic process 4/313 40/18722 0.00436060723324191 0.0515553780650681 TPI1/PYGL/PGAM1/AGL 4 GO:1901020 negative regulation of calcium ion transmembrane transporter activity 4/313 40/18722 0.00436060723324191 0.0515553780650681 C4orf3/GSTO1/SRI/CALM1 4 GO:0033500 carbohydrate homeostasis 11/313 259/18722 0.0043751893859345 0.051567634650937 DYNLL1/PYGL/SRI/SOX4/SLC16A1/PHPT1/INSR/MPC2/HMGN3/TRA2B/FAM3B 11 GO:0006753 nucleoside phosphate metabolic process 17/313 497/18722 0.00439040359721418 0.0515872422672667 GAPDH/LDHA/ALDOA/CROT/PKM/TPI1/ENO1/PGAM1/SLC26A2/INSR/PGK1/RHOA/TMSB4X/PDE4B/PARP1/MPC2/TECR 17 GO:0006575 cellular modified amino acid metabolic process 9/313 188/18722 0.00446969135019607 0.0523572768313736 CROT/SLC6A8/CLIC3/GSTO1/GPX1/IDH1/GPX4/SERINC5/CLIC1 9 GO:0007346 regulation of mitotic cell cycle 16/313 457/18722 0.00452875972357814 0.0528864670787177 IGF2/NEK6/ANXA1/TIMP2/CAV2/BTG3/SOX4/INSR/PPP1R10/BTG2/ADAMTS1/PLK2/ID2/LGMN/CCNB1/HES1 16 GO:0032984 protein-containing complex disassembly 10/313 224/18722 0.00457552408190613 0.0532691748618245 STMN3/RPL23/CCSAP/CFL1/INSR/SCIN/CALM1/EIF5A/CLN3/STMN1 10 GO:0033692 cellular polysaccharide biosynthetic process 5/313 65/18722 0.0046071755205742 0.053474137825689 IGF2/UGP2/INSR/AGL/B3GNT2 5 GO:0006690 icosanoid metabolic process 7/313 123/18722 0.00465299477862489 0.0537271001094976 CYP2J2/ANXA1/GPX1/MIF/TNFRSF1A/GPX4/AKR1B1 7 GO:0045185 maintenance of protein location 6/313 93/18722 0.00469953357931776 0.0537271001094976 CAV1/FBN1/SRI/TMSB4X/SCIN/GJA1 6 GO:0051591 response to cAMP 6/313 93/18722 0.00469953357931776 0.0537271001094976 LDHA/FOS/JUN/BSG/FOSB/EZR 6 GO:1901019 regulation of calcium ion transmembrane transporter activity 6/313 93/18722 0.00469953357931776 0.0537271001094976 C4orf3/GSTO1/SRI/PDE4B/CALM1/AHNAK 6 GO:1901796 regulation of signal transduction by p53 class mediator 6/313 93/18722 0.00469953357931776 0.0537271001094976 RPL23/DDX5/PMAIP1/MIF/PTTG1IP/EIF5A 6 GO:0009636 response to toxic substance 11/313 262/18722 0.00476566433902665 0.0542009918624125 GPX3/DHRS2/GSTO1/GPX1/FOS/PRDX1/GPX4/SOD3/PRDX6/DNMT3A/CCNB1 11 GO:1901385 regulation of voltage-gated calcium channel activity 4/313 41/18722 0.00476945948881224 0.0542009918624125 SRI/PDE4B/CALM1/AHNAK 4 GO:0097237 cellular response to toxic substance 7/313 124/18722 0.00486265324044344 0.0550955978760958 GPX3/GSTO1/GPX1/PRDX1/GPX4/SOD3/PRDX6 7 GO:0043588 skin development 11/313 263/18722 0.00490179643574877 0.0552662352530617 FLNB/ANXA1/DSP/CLIC4/DHCR24/LGR5/LSR/ARRDC3/ERRFI1/STMN1/FERMT1 11 GO:0030198 extracellular matrix organization 12/313 301/18722 0.00492126444727815 0.0552662352530617 CAV1/CCDC80/P4HA1/COL14A1/TNFRSF1A/CAV2/FBLN1/ADAMTS6/ITGB1/ADAMTSL4/ADAMTS1/FERMT1 12 GO:0042886 amide transport 12/313 301/18722 0.00492126444727815 0.0552662352530617 DYNLL1/ANXA1/SRI/ISL1/SOX4/SLC16A1/PHPT1/SLC13A3/MPC2/GJA1/HMGN3/FAM3B 12 GO:0051702 biological process involved in interaction with symbiont 6/313 94/18722 0.00495115776233834 0.0552758287425867 GAPDH/FN1/GPX1/JUN/CAV2/CFL1 6 GO:1902414 protein localization to cell junction 6/313 94/18722 0.00495115776233834 0.0552758287425867 ACTG1/DSP/HSPB1/LSR/ACTB/JAM3 6 GO:0043062 extracellular structure organization 12/313 302/18722 0.00505044146686259 0.0562193879074441 CAV1/CCDC80/P4HA1/COL14A1/TNFRSF1A/CAV2/FBLN1/ADAMTS6/ITGB1/ADAMTSL4/ADAMTS1/FERMT1 12 GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II 4/313 42/18722 0.00520329287879315 0.057519226470319 FOS/JUN/EGR1/NR3C1 4 GO:1902903 regulation of supramolecular fiber organization 14/313 382/18722 0.00521077787293739 0.057519226470319 ACTG1/GPX1/COTL1/PFN1/RHOA/TMSB4X/SCIN/S100A10/HSPA1A/TPM1/STMN1/IQGAP2/CLU/KANK4 14 GO:0007044 cell-substrate junction assembly 6/313 95/18722 0.00521253825381141 0.057519226470319 ACTG1/FN1/RHOA/S100A10/DST/PTPRA 6 GO:0035914 skeletal muscle cell differentiation 5/313 67/18722 0.00524351589148453 0.0575275648382756 DDX5/FOS/HMG20B/BTG2/EGR1 5 GO:1903317 regulation of protein maturation 5/313 67/18722 0.00524351589148453 0.0575275648382756 ENO1/SERPINE1/SOX4/MYH9/CLN3 5 GO:0001935 endothelial cell proliferation 9/313 193/18722 0.00529575636662653 0.0578328075707228 IGF2/CAV1/NRP2/PDCD6/CAV2/VEGFB/PGF/FLT1/GJA1 9 GO:2001235 positive regulation of apoptotic signaling pathway 7/313 126/18722 0.00530322181027 0.0578328075707228 CAV1/PMAIP1/TIMP3/MAGED1/CTSC/TNFRSF12A/EIF5A 7 GO:0045229 external encapsulating structure organization 12/313 304/18722 0.00531691164952797 0.0578328075707228 CAV1/CCDC80/P4HA1/COL14A1/TNFRSF1A/CAV2/FBLN1/ADAMTS6/ITGB1/ADAMTSL4/ADAMTS1/FERMT1 12 GO:0032412 regulation of ion transmembrane transporter activity 11/313 267/18722 0.00547745701875416 0.0593799732319597 CAV1/FXYD3/C4orf3/GSTO1/TCAF1/SRI/ITGB1/TMSB4X/PDE4B/CALM1/AHNAK 11 GO:0030048 actin filament-based movement 7/313 127/18722 0.00553442195399952 0.0593799732319597 CAV1/DSP/SRI/MYH9/PDE4B/TPM1/GJA1 7 GO:0061564 axon development 16/313 467/18722 0.00555146331058681 0.0593799732319597 EFNB1/FN1/NRP2/BSG/S100A6/LAMC2/SEMA6D/ISL1/C12orf57/NREP/STK24/ITGB1/ACTB/JAM3/STMN1/B3GNT2 16 GO:0035637 multicellular organismal signaling 8/313 160/18722 0.00556912776890635 0.0593799732319597 CAV1/ATP2B1/DSP/SRI/ISL1/CALM1/GJA1/JAM3 8 GO:0043271 negative regulation of ion transport 8/313 160/18722 0.00556912776890635 0.0593799732319597 CAV1/C4orf3/GSTO1/SRI/TMBIM6/SLC43A2/CALM1/RGS2 8 GO:0051148 negative regulation of muscle cell differentiation 5/313 68/18722 0.00558393233964843 0.0593799732319597 IGF2/YBX1/BHLHE41/ID2/RGS2 5 GO:0051926 negative regulation of calcium ion transport 5/313 68/18722 0.00558393233964843 0.0593799732319597 C4orf3/GSTO1/SRI/TMBIM6/CALM1 5 GO:0060411 cardiac septum morphogenesis 5/313 68/18722 0.00558393233964843 0.0593799732319597 NRP2/ISL1/SOX4/TGFBR3/HES1 5 GO:0019400 alditol metabolic process 3/313 22/18722 0.00563142705030311 0.0593873761232796 TPI1/AKR1B1/PGP 3 GO:0060343 trabecula formation 3/313 22/18722 0.00563142705030311 0.0593873761232796 FHL2/TGFBR3/ADAMTS1 3 GO:0099563 modification of synaptic structure 3/313 22/18722 0.00563142705030311 0.0593873761232796 PFN1/RHOA/CLN3 3 GO:0061383 trabecula morphogenesis 4/313 43/18722 0.00566276967381354 0.0595529396359341 RHOA/FHL2/TGFBR3/ADAMTS1 4 GO:0014909 smooth muscle cell migration 6/313 97/18722 0.00576543827685688 0.0600496340943868 IGFBP3/SERPINE1/SEMA6D/RHOA/TPM1/ADAMTS1 6 GO:0070252 actin-mediated cell contraction 6/313 97/18722 0.00576543827685688 0.0600496340943868 CAV1/DSP/SRI/PDE4B/TPM1/GJA1 6 GO:1901216 positive regulation of neuron death 6/313 97/18722 0.00576543827685688 0.0600496340943868 FOS/JUN/RHOA/PARP1/EGR1/CLU 6 GO:0001952 regulation of cell-matrix adhesion 7/313 128/18722 0.00577309326990953 0.0600496340943868 PLEKHA2/ACTG1/SERPINE1/RHOA/S100A10/PTPRA/FERMT1 7 GO:0006006 glucose metabolic process 9/313 196/18722 0.00584533377170714 0.0604706132306768 GAPDH/IGF2/TPI1/ENO1/PMAIP1/PHLDA2/INSR/PGK1/PGP 9 GO:0090276 regulation of peptide hormone secretion 9/313 196/18722 0.00584533377170714 0.0604706132306768 DYNLL1/SRI/ISL1/SOX4/SLC16A1/PHPT1/MPC2/GJA1/HMGN3 9 GO:0034101 erythrocyte homeostasis 7/313 129/18722 0.00601938155400542 0.0619584893419721 RPS17/PRDX1/PRMT1/UBA5/HSPA1A/TGFBR3/ID2 7 GO:0022604 regulation of cell morphogenesis 12/313 309/18722 0.00603227669345295 0.0619584893419721 ALDOA/FN1/ANXA1/FBLN1/CFL1/EZR/MYH9/RHOA/S100A10/TPM1/EPB41L3/RHOB 12 GO:0071248 cellular response to metal ion 9/313 197/18722 0.00603798254422686 0.0619584893419721 HSD17B1/FOS/JUN/FUS/FOSB/CLIC4/PARP1/LGMN/CCNB1 9 GO:0005978 glycogen biosynthetic process 4/313 44/18722 0.00614853619658583 0.0624199394677394 IGF2/UGP2/INSR/AGL 4 GO:0009250 glucan biosynthetic process 4/313 44/18722 0.00614853619658583 0.0624199394677394 IGF2/UGP2/INSR/AGL 4 GO:0021762 substantia nigra development 4/313 44/18722 0.00614853619658583 0.0624199394677394 DYNLL1/RHOA/CALM1/ACTB 4 GO:0089718 amino acid import across plasma membrane 4/313 44/18722 0.00614853619658583 0.0624199394677394 SLC7A5/ITGB1/SLC43A2/RGS2 4 GO:0051047 positive regulation of secretion 12/313 310/18722 0.00618410258635488 0.0626140386868431 WLS/DYNLL1/CYP19A1/SRI/ISL1/SOX4/PHPT1/EZR/SCIN/MPC2/GJA1/EXOC1 12 GO:0072331 signal transduction by p53 class mediator 8/313 163/18722 0.00621266611885119 0.062736392346065 RPL23/DDX5/PMAIP1/MIF/PTTG1IP/SOX4/EIF5A/PLK2 8 GO:0060415 muscle tissue morphogenesis 5/313 70/18722 0.00631102868127978 0.0635610745757464 LY6E/DSP/ISL1/TPM1/TGFBR3 5 GO:0033209 tumor necrosis factor-mediated signaling pathway 6/313 99/18722 0.00635997148966281 0.0638849906626552 KRT8/KRT18/TNFRSF1A/TMSB4X/HSPA1A/EIF5A 6 GO:2001169 regulation of ATP biosynthetic process 3/313 23/18722 0.00639695483377801 0.0640873869794549 ENO1/TMSB4X/PARP1 3 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 8/313 164/18722 0.00643925373965397 0.064341834611188 CAV1/RPL23/DDA1/HERPUD1/HSPA1A/CDC20/CLU/PLK2 8 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 7/313 131/18722 0.00653539319521377 0.0651158255496229 PEG10/HTRA1/CAV1/FBN1/CAV2/HSPA1A/TGFBR3 7 GO:0048762 mesenchymal cell differentiation 10/313 236/18722 0.00655092229721712 0.0651158255496229 EFNB1/FN1/DDX5/NRP2/PDCD6/SEMA6D/ISL1/HNRNPAB/TGFBR3/HES1 10 GO:0002791 regulation of peptide secretion 9/313 200/18722 0.00664540084221365 0.0654783586703833 DYNLL1/SRI/ISL1/SOX4/SLC16A1/PHPT1/MPC2/GJA1/HMGN3 9 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 4/313 45/18722 0.00666122229827244 0.0654783586703833 GPX1/STK24/HSPB1/PARP1 4 GO:0045933 positive regulation of muscle contraction 4/313 45/18722 0.00666122229827244 0.0654783586703833 ENO1/GSTO1/RHOA/RGS2 4 GO:0045807 positive regulation of endocytosis 6/313 100/18722 0.00667339195274723 0.0654783586703833 CD63/SERPINE1/INSR/CD151/CLN3/CLU 6 GO:0110020 regulation of actomyosin structure organization 6/313 100/18722 0.00667339195274723 0.0654783586703833 ACTG1/PFN1/RHOA/S100A10/TPM1/STMN1 6 GO:0060249 anatomical structure homeostasis 12/313 314/18722 0.00682193855170057 0.0667638047977483 ALDOA/ACTG1/ATP2B1/PRDX1/ITGB1/AKR1B1/HSPB1/LSR/ACTB/GJA1/JAM3/SLC2A1 12 GO:0048732 gland development 15/313 436/18722 0.00688250001909817 0.0671837886479659 IGF2/CAV1/WLS/KRT18/LBH/ANXA1/LY6E/GPX1/LMO4/ISL1/CEBPB/LSR/TGFBR3/ID2/HES1 15 GO:0150115 cell-substrate junction organization 6/313 101/18722 0.00699786927054289 0.068135264227511 ACTG1/FN1/RHOA/S100A10/DST/PTPRA 6 GO:0090087 regulation of peptide transport 9/313 202/18722 0.00707570086876946 0.0686239319179517 DYNLL1/SRI/ISL1/SOX4/SLC16A1/PHPT1/MPC2/GJA1/HMGN3 9 GO:0000271 polysaccharide biosynthetic process 5/313 72/18722 0.00710213532326582 0.0686239319179517 IGF2/UGP2/INSR/AGL/B3GNT2 5 GO:1903036 positive regulation of response to wounding 5/313 72/18722 0.00710213532326582 0.0686239319179517 ACTG1/ANXA1/SERPINE1/ITGB1/FERMT1 5 GO:0110053 regulation of actin filament organization 11/313 277/18722 0.00715154505831718 0.0689264102202874 ACTG1/COTL1/PFN1/RHOA/TMSB4X/SCIN/S100A10/TPM1/STMN1/IQGAP2/KANK4 11 GO:2001026 regulation of endothelial cell chemotaxis 3/313 24/18722 0.00722149008887785 0.0694247797180757 TMSB4X/HSPB1/LGMN 3 GO:1904062 regulation of cation transmembrane transport 13/313 357/18722 0.00734386077138477 0.0704233701679139 CAV1/FXYD3/C4orf3/CD63/GSTO1/SRI/ITGB1/TMSB4X/PDE4B/SLC43A2/CALM1/AHNAK/RGS2 13 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 7/313 134/18722 0.00737019173038272 0.0704982912501684 CAV1/DDA1/HERPUD1/HSPA1A/CDC20/CLU/PLK2 7 GO:0015980 energy derivation by oxidation of organic compounds 12/313 318/18722 0.00751061216435762 0.0712396872996747 IGF2/PYGL/PHLDA2/IDH1/UGP2/UQCRB/COX4I1/INSR/RHOA/AGL/NDUFB1/CCNB1 12 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 5/313 73/18722 0.00752255169279465 0.0712396872996747 DYNLL1/SRI/PHPT1/MPC2/HMGN3 5 GO:0042274 ribosomal small subunit biogenesis 5/313 73/18722 0.00752255169279465 0.0712396872996747 RPS27/RPS17/RPS21/RPL38/RPS28 5 GO:0086003 cardiac muscle cell contraction 5/313 73/18722 0.00752255169279465 0.0712396872996747 CAV1/DSP/SRI/PDE4B/GJA1 5 GO:0002687 positive regulation of leukocyte migration 7/313 135/18722 0.0076652511922951 0.0719404921002238 CD99/SERPINE1/VEGFB/PGF/RHOA/JAM3/LGMN 7 GO:0071900 regulation of protein serine/threonine kinase activity 13/313 359/18722 0.00767824039418466 0.0719404921002238 IGF2/CAV1/INSR/MAGED1/RHOA/FLT1/CALM1/ACTB/MAP3K4/SERTAD1/CCNL1/CCNB1/RGS2 13 GO:0002027 regulation of heart rate 6/313 103/18722 0.00768085280940863 0.0719404921002238 CAV1/DSP/SRI/ISL1/TPM1/CALM1 6 GO:0045639 positive regulation of myeloid cell differentiation 6/313 103/18722 0.00768085280940863 0.0719404921002238 FOS/JUN/PRMT1/SCIN/HSPA1A/ID2 6 GO:1901214 regulation of neuron death 12/313 319/18722 0.0076910376371923 0.0719404921002238 FOS/JUN/ISL1/DHCR24/RHOA/CEBPB/PARP1/BTG2/CLN3/EGR1/CLU/LGMN 12 GO:0048483 autonomic nervous system development 4/313 47/18722 0.00776978746887876 0.0721453192537108 FN1/NRP2/SOX4/HES1 4 GO:1900744 regulation of p38MAPK cascade 4/313 47/18722 0.00776978746887876 0.0721453192537108 GADD45B/EZR/PRMT1/MAP3K4 4 GO:1903170 negative regulation of calcium ion transmembrane transport 4/313 47/18722 0.00776978746887876 0.0721453192537108 C4orf3/GSTO1/SRI/CALM1 4 GO:0003158 endothelium development 7/313 136/18722 0.00796895081611934 0.0736354265945785 GPX1/TNFRSF1A/CLIC4/EZR/RHOA/GJA1/RHOB 7 GO:0043401 steroid hormone mediated signaling pathway 7/313 136/18722 0.00796895081611934 0.0736354265945785 LBH/DDX5/ISL1/UBA5/RHOA/PARP1/NR3C1 7 GO:0048863 stem cell differentiation 9/313 206/18722 0.00800003412060836 0.0737436559253173 EFNB1/FN1/KRT18/LBH/NRP2/PDCD6/SEMA6D/ISL1/HES1 9 GO:0033622 integrin activation 3/313 25/18722 0.00810607011809495 0.0745406013033514 FN1/JAM3/FERMT1 3 GO:1903532 positive regulation of secretion by cell 11/313 282/18722 0.00812627856571457 0.0745463674690973 WLS/DYNLL1/CYP19A1/SRI/ISL1/SOX4/PHPT1/EZR/MPC2/GJA1/EXOC1 11 GO:0007266 Rho protein signal transduction 7/313 137/18722 0.00828143645907516 0.0756053443637869 EPS8L1/CFL1/RHOA/ITGB1/HACD3/STMN1/RHOB 7 GO:0034754 cellular hormone metabolic process 7/313 137/18722 0.00828143645907516 0.0756053443637869 RDH13/DHRS2/CYP11A1/CYP19A1/HSD17B1/AKR1B1/EGR1 7 GO:0015804 neutral amino acid transport 4/313 48/18722 0.00836683981257413 0.0758060538778971 SLC7A5/SERINC5/SLC43A2/RGS2 4 GO:0048146 positive regulation of fibroblast proliferation 4/313 48/18722 0.00836683981257413 0.0758060538778971 FN1/MIF/S100A6/CCNB1 4 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 4/313 48/18722 0.00836683981257413 0.0758060538778971 CAV1/PMAIP1/TIMP3/TNFRSF12A 4 GO:0031589 cell-substrate adhesion 13/313 363/18722 0.00838307031326364 0.0758060538778971 PLEKHA2/ACTG1/FN1/CCDC80/CD63/SERPINE1/FBLN1/RHOA/ITGB1/S100A10/PTPRA/JAM3/FERMT1 13 GO:0032231 regulation of actin filament bundle assembly 6/313 105/18722 0.00841062945500875 0.0758750387090481 ACTG1/PFN1/RHOA/S100A10/TPM1/STMN1 6 GO:0002573 myeloid leukocyte differentiation 9/313 208/18722 0.00849535729883026 0.0764582156894724 DHRS2/FBN1/FOS/JUN/MYH9/CEBPB/PARP1/ITGB8/ID2 9 GO:0072659 protein localization to plasma membrane 11/313 284/18722 0.00854389366105703 0.0767136867161418 KRT18/TNFRSF1A/PKP3/BSG/EZR/TMBIM1/ITGB1/S100A10/ACTB/CLN3/EPB41L3 11 GO:0008544 epidermis development 12/313 324/18722 0.00864482767958337 0.0773565044541055 FLNB/ANXA1/DSP/LAMC2/CLIC4/LGR5/YBX1/SVEP1/ERRFI1/MCOLN3/FERMT1/HES1 12 GO:0051402 neuron apoptotic process 10/313 246/18722 0.00865612579391882 0.0773565044541055 GAPDH/GPX1/JUN/ISL1/RHOA/CEBPB/PARP1/BTG2/CLN3/LGMN 10 GO:1902905 positive regulation of supramolecular fiber organization 9/313 209/18722 0.00875159143639614 0.0774935477789792 GPX1/PFN1/RHOA/SCIN/S100A10/HSPA1A/TPM1/IQGAP2/CLU 9 GO:0006694 steroid biosynthetic process 8/313 173/18722 0.0087708081851644 0.0774935477789792 CYP11A1/CYP19A1/HSD17B1/SLC27A2/DHCR24/AKR1B1/CYB5R1/EGR1 8 GO:0051099 positive regulation of binding 8/313 173/18722 0.0087708081851644 0.0774935477789792 CAV1/ISL1/S100A10/PARP1/CALM1/STMN1/PLK2/HES1 8 GO:0030038 contractile actin filament bundle assembly 6/313 106/18722 0.00879359407421041 0.0774935477789792 ACTG1/PFN1/RHOA/S100A10/TPM1/STMN1 6 GO:0043149 stress fiber assembly 6/313 106/18722 0.00879359407421041 0.0774935477789792 ACTG1/PFN1/RHOA/S100A10/TPM1/STMN1 6 GO:0046620 regulation of organ growth 6/313 106/18722 0.00879359407421041 0.0774935477789792 IGF2/YBX3/GJA1/TGFBR3/CCNB1/RGS2 6 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 5/313 76/18722 0.00888728371013532 0.0779627802909297 DDX5/PMAIP1/MIF/PTTG1IP/EIF5A 5 GO:0006692 prostanoid metabolic process 4/313 49/18722 0.00899315754729066 0.0779627802909297 ANXA1/MIF/TNFRSF1A/AKR1B1 4 GO:0006693 prostaglandin metabolic process 4/313 49/18722 0.00899315754729066 0.0779627802909297 ANXA1/MIF/TNFRSF1A/AKR1B1 4 GO:0046580 negative regulation of Ras protein signal transduction 4/313 49/18722 0.00899315754729066 0.0779627802909297 STMN3/TIMP2/ITGB1/STMN1 4 GO:0002685 regulation of leukocyte migration 9/313 210/18722 0.00901364888772483 0.0779627802909297 ANXA1/MIF/CD99/SERPINE1/VEGFB/PGF/RHOA/JAM3/LGMN 9 GO:0031396 regulation of protein ubiquitination 9/313 210/18722 0.00901364888772483 0.0779627802909297 CAV1/RPL23/PDCD6/PTTG1IP/SOX4/HERPUD1/HSPA1A/CDC20/ARRDC3 9 GO:0045637 regulation of myeloid cell differentiation 9/313 210/18722 0.00901364888772483 0.0779627802909297 FBN1/FOS/JUN/CSF3R/PRMT1/CEBPB/SCIN/HSPA1A/ID2 9 GO:0033598 mammary gland epithelial cell proliferation 3/313 26/18722 0.00905162828699525 0.0779627802909297 GPX1/CEBPB/ID2 3 GO:0046697 decidualization 3/313 26/18722 0.00905162828699525 0.0779627802909297 STC2/BSG/GJA1 3 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 3/313 26/18722 0.00905162828699525 0.0779627802909297 GSTO1/SRI/CALM1 3 GO:0033002 muscle cell proliferation 10/313 248/18722 0.00913327298117174 0.078259733723753 IGFBP3/JUN/RHOA/AKR1B1/TPM1/GJA1/TGFBR3/ADAMTS1/ID2/CCNB1 10 GO:0051271 negative regulation of cellular component movement 13/313 367/18722 0.00913791686711066 0.078259733723753 IGFBP3/MIF/TCAF1/SERPINE1/SEMA6D/FBLN1/CLIC4/RHOA/STK24/TPM1/GJA1/TGFBR3/RHOB 13 GO:0008637 apoptotic mitochondrial changes 6/313 107/18722 0.00918888914486934 0.078259733723753 PMAIP1/GPX1/JUN/HSPA1A/NMT1/CLU 6 GO:0010927 cellular component assembly involved in morphogenesis 6/313 107/18722 0.00918888914486934 0.078259733723753 KRT19/KRT8/ACTG1/ITGB1/TPM1/EPB41L3 6 GO:0031532 actin cytoskeleton reorganization 6/313 107/18722 0.00918888914486934 0.078259733723753 ANXA1/PHPT1/EZR/MYH9/RHOA/IQGAP2 6 GO:0042180 cellular ketone metabolic process 9/313 211/18722 0.00928161096838121 0.0788729753496144 CAV1/TPI1/CYP11A1/ANXA1/HSD17B1/AKR1B1/CLN3/NMT1/EGR1 9 GO:0048644 muscle organ morphogenesis 5/313 77/18722 0.00937778322043792 0.0795127410249603 LY6E/DSP/ISL1/TPM1/TGFBR3 5 GO:0035296 regulation of tube diameter 7/313 141/18722 0.00962214643882483 0.0812228636199693 CAV1/GPX1/ATP2B1/SOD3/RHOA/GJA1/RGS2 7 GO:0097746 blood vessel diameter maintenance 7/313 141/18722 0.00962214643882483 0.0812228636199693 CAV1/GPX1/ATP2B1/SOD3/RHOA/GJA1/RGS2 7 GO:0050873 brown fat cell differentiation 4/313 50/18722 0.00964928188065317 0.0812717170788642 PLAC8/CEBPB/ARL4A/RGS2 4 GO:0043534 blood vessel endothelial cell migration 8/313 176/18722 0.00967317562054546 0.0812931116720012 ANXA1/GPX1/MYH9/RHOA/ITGB1/TMSB4X/HSPB1/PLK2 8 GO:0008306 associative learning 5/313 78/18722 0.00988661278881333 0.0825436494367744 FOS/ITGB1/BTG2/CLN3/LGMN 5 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 5/313 78/18722 0.00988661278881333 0.0825436494367744 SERPINB9/GPX1/DHCR24/HERPUD1/BIRC5 5 GO:0071375 cellular response to peptide hormone stimulus 11/313 290/18722 0.00989718070244516 0.0825436494367744 IGF2/PKM/CAV1/CYP11A1/FBN1/ATP2B1/CAV2/INSR/PTPRA/PARP1/ERRFI1 11 GO:0048638 regulation of developmental growth 12/313 330/18722 0.00990870706398894 0.0825436494367744 PLAC8/IGF2/FN1/YBX3/SEMA6D/EZR/INSR/GJA1/TGFBR3/LGMN/CCNB1/RGS2 12 GO:0007009 plasma membrane organization 7/313 142/18722 0.0099807393174684 0.0826681317558145 CAV1/CAV2/MYH9/SPESP1/CLN3/EPB41L3/CLU 7 GO:0035150 regulation of tube size 7/313 142/18722 0.0099807393174684 0.0826681317558145 CAV1/GPX1/ATP2B1/SOD3/RHOA/GJA1/RGS2 7 GO:0051302 regulation of cell division 8/313 177/18722 0.00998879448586148 0.0826681317558145 IGF2/LBH/VEGFB/PGF/RHOA/YBX1/CALM1/PLK2 8 GO:0098901 regulation of cardiac muscle cell action potential 3/313 27/18722 0.0100589980559931 0.0828887567081513 CAV1/DSP/CALM1 3 GO:1903319 positive regulation of protein maturation 3/313 27/18722 0.0100589980559931 0.0828887567081513 ENO1/SOX4/MYH9 3 GO:0009314 response to radiation 15/313 456/18722 0.0101458982772127 0.0834242651001055 RDH13/ANXA1/GPX1/FOS/JUN/ADIRF/ITGB1/DYNLRB1/PARP1/NMT1/MAP3K4/EGR1/RHOB/ID2/DNMT3A 15 GO:0051293 establishment of spindle localization 4/313 51/18722 0.0103357353217788 0.0845463309718791 CFL1/MYH9/ITGB1/GJA1 4 GO:0006865 amino acid transport 7/313 143/18722 0.0103489861394525 0.0845463309718791 SLC7A5/SERINC5/ITGB1/SLC43A2/CLN3/GJA1/RGS2 7 GO:0030010 establishment of cell polarity 7/313 143/18722 0.0103489861394525 0.0845463309718791 MYH9/RHOA/ITGB1/GJA1/JAM3/FERMT1/HES1 7 GO:0001895 retina homeostasis 5/313 79/18722 0.0104140863904409 0.0847145873683941 ACTG1/PRDX1/HSPB1/ACTB/SLC2A1 5 GO:0032272 negative regulation of protein polymerization 5/313 79/18722 0.0104140863904409 0.0847145873683941 PFN1/TMSB4X/SCIN/STMN1/KANK4 5 GO:1990778 protein localization to cell periphery 12/313 333/18722 0.0105922007431555 0.085979761682714 CAV1/KRT18/TNFRSF1A/PKP3/BSG/EZR/TMBIM1/ITGB1/S100A10/ACTB/CLN3/EPB41L3 12 GO:0007612 learning 7/313 144/18722 0.0107270298327168 0.086888941645006 FOS/JUN/INSR/ITGB1/BTG2/CLN3/LGMN 7 GO:0001938 positive regulation of endothelial cell proliferation 6/313 111/18722 0.0108975095820182 0.0880148180100125 IGF2/NRP2/PDCD6/CAV2/VEGFB/PGF 6 GO:0048145 regulation of fibroblast proliferation 5/313 80/18722 0.010960512788468 0.0880148180100125 FN1/MIF/FTH1/S100A6/CCNB1 5 GO:0120193 tight junction organization 5/313 80/18722 0.010960512788468 0.0880148180100125 ACTG1/LSR/SVEP1/GJA1/CLDN7 5 GO:0015698 inorganic anion transport 8/313 180/18722 0.010981622945825 0.0880148180100125 FXYD3/CLIC3/CLIC4/SLC26A2/CLIC1/CEBPB/SLC13A4/SLC22A11 8 GO:0048660 regulation of smooth muscle cell proliferation 8/313 180/18722 0.010981622945825 0.0880148180100125 IGFBP3/JUN/RHOA/AKR1B1/TPM1/GJA1/ADAMTS1/ID2 8 GO:0031103 axon regeneration 4/313 52/18722 0.0110530214455172 0.0880310724750711 ISL1/NREP/STK24/JAM3 4 GO:0043090 amino acid import 4/313 52/18722 0.0110530214455172 0.0880310724750711 SLC7A5/ITGB1/SLC43A2/RGS2 4 GO:0048260 positive regulation of receptor-mediated endocytosis 4/313 52/18722 0.0110530214455172 0.0880310724750711 CD63/SERPINE1/INSR/CLU 4 GO:0090344 negative regulation of cell aging 3/313 28/18722 0.0111289168930762 0.0884504939706497 MIF/YBX1/PLK2 3 GO:0034976 response to endoplasmic reticulum stress 10/313 256/18722 0.0112460013169013 0.0891948479446732 CAV1/PMAIP1/JUN/UBA5/CEBPB/HERPUD1/HSPA1A/TMBIM6/PPP1R15A/CLU 10 GO:0002934 desmosome organization 2/313 10/18722 0.0114741729468905 0.0896964607983821 DSP/PKP3 2 GO:0003056 regulation of vascular associated smooth muscle contraction 2/313 10/18722 0.0114741729468905 0.0896964607983821 ATP2B1/RHOA 2 GO:0040015 negative regulation of multicellular organism growth 2/313 10/18722 0.0114741729468905 0.0896964607983821 PLAC8/LGMN 2 GO:0042989 sequestering of actin monomers 2/313 10/18722 0.0114741729468905 0.0896964607983821 TMSB4X/SCIN 2 GO:0072378 blood coagulation, fibrin clot formation 2/313 10/18722 0.0114741729468905 0.0896964607983821 FN1/FBLN1 2 GO:0098885 modification of postsynaptic actin cytoskeleton 2/313 10/18722 0.0114741729468905 0.0896964607983821 PFN1/RHOA 2 GO:1903867 extraembryonic membrane development 2/313 10/18722 0.0114741729468905 0.0896964607983821 HTRA1/MAP3K4 2 GO:0048144 fibroblast proliferation 5/313 81/18722 0.0115261953491503 0.089734612871606 FN1/MIF/FTH1/S100A6/CCNB1 5 GO:0051817 modulation of process of other organism involved in symbiotic interaction 5/313 81/18722 0.0115261953491503 0.089734612871606 SERPINB9/JUN/CAV2/CFL1/INSR 5 GO:0007265 Ras protein signal transduction 12/313 337/18722 0.0115596514671284 0.0898114145619548 EPS8L1/STMN3/TIMP2/JUN/CFL1/DHCR24/RHOA/ITGB1/HACD3/STMN1/RHOB/PLK2 12 GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 4/313 53/18722 0.0118016246908568 0.0915046541712662 PDE4B/ARRDC3/STMN1/RGS2 4 GO:0009205 purine ribonucleoside triphosphate metabolic process 5/313 82/18722 0.0121114318646543 0.0937158965624775 ALDOA/ENO1/RHOA/TMSB4X/PARP1 5 GO:0021522 spinal cord motor neuron differentiation 3/313 29/18722 0.0122620300705379 0.0943061585425005 LMO4/ISL1/SOX4 3 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 3/313 29/18722 0.0122620300705379 0.0943061585425005 GPX1/HSPB1/PARP1 3 GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 3/313 29/18722 0.0122620300705379 0.0943061585425005 MIF/PTTG1IP/EIF5A 3 GO:0043484 regulation of RNA splicing 7/313 148/18722 0.0123400083177561 0.0947145396485837 DDX5/FUS/HSPA1A/TMBIM6/PRDX6/TRA2B/AHNAK 7 GO:0048659 smooth muscle cell proliferation 8/313 184/18722 0.0124165947197347 0.0949196307189359 IGFBP3/JUN/RHOA/AKR1B1/TPM1/GJA1/ADAMTS1/ID2 8 GO:2001257 regulation of cation channel activity 8/313 184/18722 0.0124165947197347 0.0949196307189359 CAV1/GSTO1/SRI/ITGB1/TMSB4X/PDE4B/CALM1/AHNAK 8 GO:0010524 positive regulation of calcium ion transport into cytosol 4/313 54/18722 0.0125820101919281 0.0956082091829746 CAV1/GSTO1/SRI/CALM1 4 GO:0072348 sulfur compound transport 4/313 54/18722 0.0125820101919281 0.0956082091829746 SLC26A2/SLC13A4/SLC13A3/GJA1 4 GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II 4/313 54/18722 0.0125820101919281 0.0956082091829746 FOS/JUN/EGR1/NR3C1 4 GO:0050920 regulation of chemotaxis 9/313 223/18722 0.0129873389969893 0.0984916325927059 MIF/SERPINE1/VEGFB/SEMA6D/PGF/TMSB4X/HSPB1/JAM3/LGMN 9 GO:1900542 regulation of purine nucleotide metabolic process 5/313 84/18722 0.0133417290485165 0.100978056635591 ENO1/PGAM1/INSR/TMSB4X/PARP1 5 GO:0038066 p38MAPK cascade 4/313 55/18722 0.0133946236400905 0.101177246424255 GADD45B/EZR/PRMT1/MAP3K4 4 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 3/313 30/18722 0.0134588943487032 0.10126089088046 GSTO1/SRI/CALM1 3 GO:0061384 heart trabecula morphogenesis 3/313 30/18722 0.0134588943487032 0.10126089088046 FHL2/TGFBR3/ADAMTS1 3 GO:0061136 regulation of proteasomal protein catabolic process 8/313 187/18722 0.0135798826032464 0.101969651026744 CAV1/GPX1/DDA1/HERPUD1/HSPA1A/CDC20/CLU/PLK2 8 GO:0071333 cellular response to glucose stimulus 7/313 151/18722 0.0136595058953003 0.102334307073074 DYNLL1/SRI/SOX4/PHPT1/MPC2/HMGN3/TRA2B 7 GO:0032868 response to insulin 10/313 264/18722 0.0137102023636731 0.102334307073074 IGF2/PKM/ATP2B1/CAV2/INSR/PTPRA/PARP1/ERRFI1/EGR1/SLC2A1 10 GO:0001731 formation of translation preinitiation complex 2/313 11/18722 0.0138703710138445 0.102334307073074 EIF4H/EIF4B 2 GO:0003263 cardioblast proliferation 2/313 11/18722 0.0138703710138445 0.102334307073074 ISL1/HES1 2 GO:0003264 regulation of cardioblast proliferation 2/313 11/18722 0.0138703710138445 0.102334307073074 ISL1/HES1 2 GO:0019372 lipoxygenase pathway 2/313 11/18722 0.0138703710138445 0.102334307073074 GPX1/GPX4 2 GO:0055015 ventricular cardiac muscle cell development 2/313 11/18722 0.0138703710138445 0.102334307073074 FHL2/CCNB1 2 GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 2/313 11/18722 0.0138703710138445 0.102334307073074 PDE4B/ARRDC3 2 GO:1903961 positive regulation of anion transmembrane transport 2/313 11/18722 0.0138703710138445 0.102334307073074 TCAF1/ITGB1 2 GO:0071277 cellular response to calcium ion 5/313 85/18722 0.0139873559425224 0.102867676860821 FOS/FUS/FOSB/CLIC4/LGMN 5 GO:0071241 cellular response to inorganic substance 9/313 226/18722 0.0140649077666676 0.102867676860821 HSD17B1/FOS/JUN/FUS/FOSB/CLIC4/PARP1/LGMN/CCNB1 9 GO:0021915 neural tube development 7/313 152/18722 0.0141209817901853 0.102867676860821 LMO4/PFN1/SOX4/FKBP8/TMEM107/HES1/BRD2 7 GO:0030509 BMP signaling pathway 7/313 152/18722 0.0141209817901853 0.102867676860821 HTRA1/FBN1/DDX5/FKBP8/EGR1/TGFBR3/HES1 7 GO:0098754 detoxification 7/313 152/18722 0.0141209817901853 0.102867676860821 GPX3/GSTO1/GPX1/PRDX1/GPX4/SOD3/PRDX6 7 GO:0031122 cytoplasmic microtubule organization 4/313 56/18722 0.0142398911756377 0.102867676860821 STMN3/EZR/RHOA/DST 4 GO:0031529 ruffle organization 4/313 56/18722 0.0142398911756377 0.102867676860821 CAV1/EPS8L1/PFN1/TPM1 4 GO:0043388 positive regulation of DNA binding 4/313 56/18722 0.0142398911756377 0.102867676860821 ISL1/PARP1/CALM1/HES1 4 GO:0046622 positive regulation of organ growth 4/313 56/18722 0.0142398911756377 0.102867676860821 IGF2/YBX3/TGFBR3/CCNB1 4 GO:0051058 negative regulation of small GTPase mediated signal transduction 4/313 56/18722 0.0142398911756377 0.102867676860821 STMN3/TIMP2/ITGB1/STMN1 4 GO:0051653 spindle localization 4/313 56/18722 0.0142398911756377 0.102867676860821 CFL1/MYH9/ITGB1/GJA1 4 GO:0010639 negative regulation of organelle organization 12/313 347/18722 0.0142764632173709 0.102936544447976 GPX1/PFN1/PTTG1/TMSB4X/SCIN/HSPA1A/PARP1/STMN1/CLU/KANK4/TOP2A/CCNB1 12 GO:0071331 cellular response to hexose stimulus 7/313 153/18722 0.0145935056551301 0.104550316714897 DYNLL1/SRI/SOX4/PHPT1/MPC2/HMGN3/TRA2B 7 GO:0006140 regulation of nucleotide metabolic process 5/313 86/18722 0.0146536689412365 0.104550316714897 ENO1/PGAM1/INSR/TMSB4X/PARP1 5 GO:0015908 fatty acid transport 5/313 86/18722 0.0146536689412365 0.104550316714897 CROT/PLIN2/ANXA1/SLC27A2/SLC2A1 5 GO:0032413 negative regulation of ion transmembrane transporter activity 5/313 86/18722 0.0146536689412365 0.104550316714897 CAV1/C4orf3/GSTO1/SRI/CALM1 5 GO:2000117 negative regulation of cysteine-type endopeptidase activity 5/313 86/18722 0.0146536689412365 0.104550316714897 SERPINB9/GPX1/DHCR24/HERPUD1/BIRC5 5 GO:0090162 establishment of epithelial cell polarity 3/313 31/18722 0.0147199815495626 0.104550316714897 RHOA/FERMT1/HES1 3 GO:1900027 regulation of ruffle assembly 3/313 31/18722 0.0147199815495626 0.104550316714897 CAV1/EPS8L1/PFN1 3 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 3/313 31/18722 0.0147199815495626 0.104550316714897 GPX1/SERPINE1/TMBIM1 3 GO:0009755 hormone-mediated signaling pathway 8/313 190/18722 0.0148208912335317 0.104875711758467 LBH/DDX5/ISL1/UBA5/RHOA/LGR5/PARP1/NR3C1 8 GO:0046390 ribose phosphate biosynthetic process 8/313 190/18722 0.0148208912335317 0.104875711758467 ALDOA/PYGL/ENO1/SLC26A2/TMSB4X/PARP1/MPC2/TECR 8 GO:0040013 negative regulation of locomotion 13/313 391/18722 0.0148496976803965 0.1048845993864 IGFBP3/MIF/TCAF1/SERPINE1/SEMA6D/FBLN1/CLIC4/RHOA/STK24/TPM1/GJA1/ARRDC3/RHOB 13 GO:0071326 cellular response to monosaccharide stimulus 7/313 154/18722 0.0150772116239543 0.106148812172622 DYNLL1/SRI/SOX4/PHPT1/MPC2/HMGN3/TRA2B 7 GO:0001894 tissue homeostasis 10/313 268/18722 0.0150844516378746 0.106148812172622 ACTG1/PRDX1/ITGB1/AKR1B1/HSPB1/LSR/ACTB/GJA1/JAM3/SLC2A1 10 GO:0006754 ATP biosynthetic process 4/313 57/18722 0.0151182193077094 0.106190149270202 ALDOA/ENO1/TMSB4X/PARP1 4 GO:0050821 protein stabilization 8/313 191/18722 0.0152523080408338 0.106934690076343 GAPDH/RPL23/PFN1/AAK1/SOX4/HSPA1A/CTNND1/CLU 8 GO:0044070 regulation of anion transport 5/313 87/18722 0.0153409355737948 0.107161360971444 TCAF1/CEBPB/ITGB1/SLC43A2/RGS2 5 GO:0150104 transport across blood-brain barrier 5/313 87/18722 0.0153409355737948 0.107161360971444 SLC7A5/SLC16A1/INSR/SLC13A3/SLC2A1 5 GO:0034614 cellular response to reactive oxygen species 7/313 155/18722 0.0155722326693196 0.108577820095421 ANXA1/FOS/JUN/PRDX1/SOD3/TPM1/RHOB 7 GO:0042743 hydrogen peroxide metabolic process 4/313 58/18722 0.016029994861044 0.109758799122175 GPX3/GPX1/PRDX1/PRDX6 4 GO:0035767 endothelial cell chemotaxis 3/313 32/18722 0.0160456820231613 0.109758799122175 TMSB4X/HSPB1/LGMN 3 GO:0050685 positive regulation of mRNA processing 3/313 32/18722 0.0160456820231613 0.109758799122175 PRDX6/TRA2B/CCNB1 3 GO:0071875 adrenergic receptor signaling pathway 3/313 32/18722 0.0160456820231613 0.109758799122175 PDE4B/ARRDC3/RGS2 3 GO:0072337 modified amino acid transport 3/313 32/18722 0.0160456820231613 0.109758799122175 SLC6A8/SLC13A3/GJA1 3 GO:1900745 positive regulation of p38MAPK cascade 3/313 32/18722 0.0160456820231613 0.109758799122175 GADD45B/PRMT1/MAP3K4 3 GO:0009144 purine nucleoside triphosphate metabolic process 5/313 88/18722 0.0160494168905397 0.109758799122175 ALDOA/ENO1/RHOA/TMSB4X/PARP1 5 GO:0035051 cardiocyte differentiation 7/313 156/18722 0.0160787005539802 0.109758799122175 ISL1/ITGB1/FHL2/TGFBR3/CCNB1/RGS2/HES1 7 GO:0045931 positive regulation of mitotic cell cycle 6/313 121/18722 0.0161309722577505 0.109758799122175 ANXA1/PPP1R10/ADAMTS1/LGMN/CCNB1/HES1 6 GO:0010594 regulation of endothelial cell migration 9/313 232/18722 0.0164165949945671 0.109758799122175 NRP2/ANXA1/PDCD6/RHOA/TMSB4X/HSPB1/RHOB/PLK2/LGMN 9 GO:0032271 regulation of protein polymerization 9/313 232/18722 0.0164165949945671 0.109758799122175 COTL1/PFN1/RHOA/TMSB4X/SCIN/HSPA1A/STMN1/IQGAP2/KANK4 9 GO:0002328 pro-B cell differentiation 2/313 12/18722 0.0164623783290681 0.109758799122175 SOX4/HES1 2 GO:0006703 estrogen biosynthetic process 2/313 12/18722 0.0164623783290681 0.109758799122175 CYP19A1/HSD17B1 2 GO:0031953 negative regulation of protein autophosphorylation 2/313 12/18722 0.0164623783290681 0.109758799122175 CAV1/ERRFI1 2 GO:0033629 negative regulation of cell adhesion mediated by integrin 2/313 12/18722 0.0164623783290681 0.109758799122175 SERPINE1/JAM3 2 GO:0034333 adherens junction assembly 2/313 12/18722 0.0164623783290681 0.109758799122175 ACTB/JAM3 2 GO:0048548 regulation of pinocytosis 2/313 12/18722 0.0164623783290681 0.109758799122175 CAV1/CLN3 2 GO:0060019 radial glial cell differentiation 2/313 12/18722 0.0164623783290681 0.109758799122175 RHOA/HES1 2 GO:0070493 thrombin-activated receptor signaling pathway 2/313 12/18722 0.0164623783290681 0.109758799122175 STMN1/IQGAP2 2 GO:0071472 cellular response to salt stress 2/313 12/18722 0.0164623783290681 0.109758799122175 EFHD1/AKR1B1 2 GO:0072376 protein activation cascade 2/313 12/18722 0.0164623783290681 0.109758799122175 FN1/FBLN1 2 GO:0072584 caveolin-mediated endocytosis 2/313 12/18722 0.0164623783290681 0.109758799122175 CAV1/CLN3 2 GO:0098911 regulation of ventricular cardiac muscle cell action potential 2/313 12/18722 0.0164623783290681 0.109758799122175 CAV1/DSP 2 GO:0098974 postsynaptic actin cytoskeleton organization 2/313 12/18722 0.0164623783290681 0.109758799122175 ACTG1/ACTB 2 GO:1990034 calcium ion export across plasma membrane 2/313 12/18722 0.0164623783290681 0.109758799122175 ATP2B1/CALM1 2 GO:0051017 actin filament bundle assembly 7/313 157/18722 0.0165967457827241 0.110461208382571 ACTG1/PFN1/EZR/RHOA/S100A10/TPM1/STMN1 7 GO:0002688 regulation of leukocyte chemotaxis 6/313 122/18722 0.0167351487091224 0.111187977549091 MIF/SERPINE1/VEGFB/PGF/JAM3/LGMN 6 GO:0009199 ribonucleoside triphosphate metabolic process 5/313 89/18722 0.0167793673380951 0.111287546090815 ALDOA/ENO1/RHOA/TMSB4X/PARP1 5 GO:0045936 negative regulation of phosphate metabolic process 14/313 441/18722 0.0168793533781202 0.111755997061746 CAV1/IGFBP3/DYNLL1/MLLT1/GADD45B/FBLN1/FKBP8/HSPB1/PARP1/CALM1/PPP1R15A/ERRFI1/CCNB1/RGS2 14 GO:0001836 release of cytochrome c from mitochondria 4/313 59/18722 0.0169755849482557 0.112003556149063 PMAIP1/GPX1/JUN/CLU 4 GO:2001258 negative regulation of cation channel activity 4/313 59/18722 0.0169755849482557 0.112003556149063 CAV1/GSTO1/SRI/CALM1 4 GO:0010563 negative regulation of phosphorus metabolic process 14/313 442/18722 0.0171777360111984 0.113141247395557 CAV1/IGFBP3/DYNLL1/MLLT1/GADD45B/FBLN1/FKBP8/HSPB1/PARP1/CALM1/PPP1R15A/ERRFI1/CCNB1/RGS2 14 GO:0030168 platelet activation 6/313 123/18722 0.0173547463465838 0.114109705252926 ACTG1/FN1/MYH9/CLIC1/HSPB1/ACTB 6 GO:0042475 odontogenesis of dentin-containing tooth 5/313 90/18722 0.0175310346416326 0.114872029054553 HTRA1/BSG/SERPINE1/CSF3R/ANKRD11 5 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 5/313 90/18722 0.0175310346416326 0.114872029054553 JUN/RHOA/TPM1/GJA1/ADAMTS1 5 GO:0035966 response to topologically incorrect protein 7/313 159/18722 0.0176680837184212 0.115548476035748 HERPUD1/HSPA1A/HSPB1/TMBIM6/PPP1R15A/DNAJB4/CLU 7 GO:2000116 regulation of cysteine-type endopeptidase activity 9/313 235/18722 0.0176949728208146 0.115548476035748 SERPINB9/PMAIP1/GPX1/PDCD6/DHCR24/RHOA/HERPUD1/BIRC5/LGMN 9 GO:0043270 positive regulation of ion transport 10/313 275/18722 0.0177330457962187 0.115598810524323 CAV1/GSTO1/ATP2B1/TCAF1/SRI/CEBPB/ITGB1/TMSB4X/CALM1/PRSS8 10 GO:0031102 neuron projection regeneration 4/313 60/18722 0.0179553369663629 0.116847808258023 ISL1/NREP/STK24/JAM3 4 GO:2000146 negative regulation of cell motility 12/313 359/18722 0.0181497209956317 0.117911242031348 IGFBP3/MIF/TCAF1/SERPINE1/SEMA6D/FBLN1/CLIC4/RHOA/STK24/TPM1/GJA1/RHOB 12 GO:0055006 cardiac cell development 5/313 91/18722 0.018304659694244 0.118513332408141 ISL1/FHL2/TGFBR3/CCNB1/RGS2 5 GO:1990874 vascular associated smooth muscle cell proliferation 5/313 91/18722 0.018304659694244 0.118513332408141 JUN/RHOA/TPM1/GJA1/ADAMTS1 5 GO:0061572 actin filament bundle organization 7/313 161/18722 0.0187872635745234 0.119312999580727 ACTG1/PFN1/EZR/RHOA/S100A10/TPM1/STMN1 7 GO:0000038 very long-chain fatty acid metabolic process 3/313 34/18722 0.0188920968988086 0.119312999580727 SLC27A2/TECR/HACD3 3 GO:0010614 negative regulation of cardiac muscle hypertrophy 3/313 34/18722 0.0188920968988086 0.119312999580727 TNFRSF1A/ERRFI1/RGS2 3 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 3/313 34/18722 0.0188920968988086 0.119312999580727 GSTO1/SRI/CALM1 3 GO:0044319 wound healing, spreading of cells 3/313 34/18722 0.0188920968988086 0.119312999580727 CD151/RHOA/FERMT1 3 GO:0090075 relaxation of muscle 3/313 34/18722 0.0188920968988086 0.119312999580727 SRI/PDE4B/RGS2 3 GO:0090505 epiboly involved in wound healing 3/313 34/18722 0.0188920968988086 0.119312999580727 CD151/RHOA/FERMT1 3 GO:0030865 cortical cytoskeleton organization 4/313 61/18722 0.0189695786163424 0.119312999580727 EZR/RHOA/EPB41L3/RHOB 4 GO:0040014 regulation of multicellular organism growth 4/313 61/18722 0.0189695786163424 0.119312999580727 PLAC8/IGF2/EZR/LGMN 4 GO:0090342 regulation of cell aging 4/313 61/18722 0.0189695786163424 0.119312999580727 NEK6/MIF/YBX1/PLK2 4 GO:0009896 positive regulation of catabolic process 15/313 492/18722 0.0189845834115574 0.119312999580727 CAV1/PTTG1IP/DDA1/OAZ1/EZR/INSR/CTSC/HERPUD1/HSPA1A/BTG2/CDC20/GJA1/KCNQ1OT1/CLU/PLK2 15 GO:0002551 mast cell chemotaxis 2/313 13/18722 0.0192430212089747 0.119312999580727 VEGFB/PGF 2 GO:0006000 fructose metabolic process 2/313 13/18722 0.0192430212089747 0.119312999580727 ALDOA/AKR1B1 2 GO:0010755 regulation of plasminogen activation 2/313 13/18722 0.0192430212089747 0.119312999580727 ENO1/SERPINE1 2 GO:0030497 fatty acid elongation 2/313 13/18722 0.0192430212089747 0.119312999580727 TECR/HACD3 2 GO:0042538 hyperosmotic salinity response 2/313 13/18722 0.0192430212089747 0.119312999580727 EFHD1/AKR1B1 2 GO:0042761 very long-chain fatty acid biosynthetic process 2/313 13/18722 0.0192430212089747 0.119312999580727 TECR/HACD3 2 GO:0042769 DNA damage response, detection of DNA damage 2/313 13/18722 0.0192430212089747 0.119312999580727 SOX4/PARP1 2 GO:0044794 positive regulation by host of viral process 2/313 13/18722 0.0192430212089747 0.119312999580727 CAV2/CFL1 2 GO:0048711 positive regulation of astrocyte differentiation 2/313 13/18722 0.0192430212089747 0.119312999580727 ID2/HES1 2 GO:0051956 negative regulation of amino acid transport 2/313 13/18722 0.0192430212089747 0.119312999580727 SLC43A2/RGS2 2 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 2/313 13/18722 0.0192430212089747 0.119312999580727 BACH1/EGR1 2 GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 2/313 13/18722 0.0192430212089747 0.119312999580727 PDE4B/ARRDC3 2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 2/313 13/18722 0.0192430212089747 0.119312999580727 PMAIP1/TIMP3 2 GO:1902947 regulation of tau-protein kinase activity 2/313 13/18722 0.0192430212089747 0.119312999580727 EGR1/CLU 2 GO:1905244 regulation of modification of synaptic structure 2/313 13/18722 0.0192430212089747 0.119312999580727 RHOA/CLN3 2 GO:0021953 central nervous system neuron differentiation 7/313 162/18722 0.0193651057936302 0.119486155196678 NRP2/LMO4/ISL1/SOX4/C12orf57/BTG2/HES1 7 GO:0034250 positive regulation of cellular amide metabolic process 7/313 162/18722 0.0193651057936302 0.119486155196678 PKM/YBX3/SOX4/RHOA/EIF5A/PPP1R15A/CLU 7 GO:0051100 negative regulation of binding 7/313 162/18722 0.0193651057936302 0.119486155196678 CAV1/C4orf3/JUN/SRI/TMSB4X/TMBIM6/ACTB 7 GO:0072593 reactive oxygen species metabolic process 9/313 239/18722 0.0195105074135334 0.120188514115407 GPX3/PAGE4/PMAIP1/GPX1/PRDX1/SOD3/RHOA/STK17A/PRDX6 9 GO:0071902 positive regulation of protein serine/threonine kinase activity 8/313 200/18722 0.0195538001957545 0.120260609604584 IGF2/INSR/MAGED1/RHOA/FLT1/CALM1/MAP3K4/CCNB1 8 GO:0071322 cellular response to carbohydrate stimulus 7/313 163/18722 0.0199552793687806 0.122531852511206 DYNLL1/SRI/SOX4/PHPT1/MPC2/HMGN3/TRA2B 7 GO:0045428 regulation of nitric oxide biosynthetic process 4/313 62/18722 0.0200186179445243 0.122722831746866 CAV1/DYNLL1/INSR/CLU 4 GO:0001893 maternal placenta development 3/313 35/18722 0.020413214392403 0.123746985974328 STC2/BSG/GJA1 3 GO:0018149 peptide cross-linking 3/313 35/18722 0.020413214392403 0.123746985974328 FN1/ANXA1/DSP 3 GO:0045454 cell redox homeostasis 3/313 35/18722 0.020413214392403 0.123746985974328 GPX1/PRDX1/PRDX6 3 GO:0045907 positive regulation of vasoconstriction 3/313 35/18722 0.020413214392403 0.123746985974328 CAV1/RHOA/GJA1 3 GO:0090504 epiboly 3/313 35/18722 0.020413214392403 0.123746985974328 CD151/RHOA/FERMT1 3 GO:1903514 release of sequestered calcium ion into cytosol by endoplasmic reticulum 3/313 35/18722 0.020413214392403 0.123746985974328 GSTO1/SRI/CALM1 3 GO:1905898 positive regulation of response to endoplasmic reticulum stress 3/313 35/18722 0.020413214392403 0.123746985974328 CAV1/PMAIP1/HERPUD1 3 GO:0050680 negative regulation of epithelial cell proliferation 7/313 164/18722 0.0205579047153021 0.124425982911216 CAV1/CAV2/ISL1/MAGED1/FLT1/GJA1/TGFBR3 7 GO:0032612 interleukin-1 production 6/313 128/18722 0.0206899804180485 0.124828455549145 ANXA1/SERPINB1/ISL1/HSPB1/ERRFI1/EGR1 6 GO:0032652 regulation of interleukin-1 production 6/313 128/18722 0.0206899804180485 0.124828455549145 ANXA1/SERPINB1/ISL1/HSPB1/ERRFI1/EGR1 6 GO:0032233 positive regulation of actin filament bundle assembly 4/313 63/18722 0.0211027434046865 0.126341683558608 PFN1/RHOA/S100A10/TPM1 4 GO:1902373 negative regulation of mRNA catabolic process 4/313 63/18722 0.0211027434046865 0.126341683558608 YBX3/FUS/PKP3/YBX1 4 GO:1903706 regulation of hemopoiesis 12/313 367/18722 0.0211387711898216 0.126341683558608 FBN1/ANXA1/FOS/JUN/CSF3R/SOX4/PRMT1/RHOA/CEBPB/SCIN/HSPA1A/ID2 12 GO:0032869 cellular response to insulin stimulus 8/313 203/18722 0.0211626782684313 0.126341683558608 IGF2/PKM/ATP2B1/CAV2/INSR/PTPRA/PARP1/ERRFI1 8 GO:0051701 biological process involved in interaction with host 8/313 203/18722 0.0211626782684313 0.126341683558608 SERPINB9/CAV1/LY6E/BSG/CAV2/INSR/ITGB1/HSPA1A 8 GO:0071772 response to BMP 7/313 165/18722 0.0211731006331473 0.126341683558608 HTRA1/FBN1/DDX5/FKBP8/EGR1/TGFBR3/HES1 7 GO:0071773 cellular response to BMP stimulus 7/313 165/18722 0.0211731006331473 0.126341683558608 HTRA1/FBN1/DDX5/FKBP8/EGR1/TGFBR3/HES1 7 GO:0036473 cell death in response to oxidative stress 5/313 95/18722 0.0216233105250862 0.127218054945283 PAGE4/GPX1/STK24/HSPB1/PARP1 5 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 5/313 95/18722 0.0216233105250862 0.127218054945283 CAV1/RPL23/SOX4/HMG20B/HSPA1A 5 GO:0014741 negative regulation of muscle hypertrophy 3/313 36/18722 0.0219997575674386 0.127218054945283 TNFRSF1A/ERRFI1/RGS2 3 GO:0051955 regulation of amino acid transport 3/313 36/18722 0.0219997575674386 0.127218054945283 ITGB1/SLC43A2/RGS2 3 GO:0070873 regulation of glycogen metabolic process 3/313 36/18722 0.0219997575674386 0.127218054945283 IGF2/PHLDA2/INSR 3 GO:0042476 odontogenesis 6/313 130/18722 0.0221378219633027 0.127218054945283 HTRA1/BSG/SERPINE1/CSF3R/RHOA/ANKRD11 6 GO:0043467 regulation of generation of precursor metabolites and energy 6/313 130/18722 0.0221378219633027 0.127218054945283 IGF2/PHLDA2/PGAM1/INSR/RHOA/CCNB1 6 GO:0035672 oligopeptide transmembrane transport 2/313 14/18722 0.0222053097695551 0.127218054945283 SLC13A3/GJA1 2 GO:0042415 norepinephrine metabolic process 2/313 14/18722 0.0222053097695551 0.127218054945283 LY6E/AKR1B1 2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 2/313 14/18722 0.0222053097695551 0.127218054945283 DDX5/PMAIP1 2 GO:0044764 multi-organism cellular process 2/313 14/18722 0.0222053097695551 0.127218054945283 CAV1/CAV2 2 GO:0045989 positive regulation of striated muscle contraction 2/313 14/18722 0.0222053097695551 0.127218054945283 GSTO1/RGS2 2 GO:0050930 induction of positive chemotaxis 2/313 14/18722 0.0222053097695551 0.127218054945283 VEGFB/PGF 2 GO:0097531 mast cell migration 2/313 14/18722 0.0222053097695551 0.127218054945283 VEGFB/PGF 2 GO:0099188 postsynaptic cytoskeleton organization 2/313 14/18722 0.0222053097695551 0.127218054945283 ACTG1/ACTB 2 GO:1900037 regulation of cellular response to hypoxia 2/313 14/18722 0.0222053097695551 0.127218054945283 ENO1/TMBIM6 2 GO:1901077 regulation of relaxation of muscle 2/313 14/18722 0.0222053097695551 0.127218054945283 SRI/PDE4B 2 GO:1904294 positive regulation of ERAD pathway 2/313 14/18722 0.0222053097695551 0.127218054945283 CAV1/HERPUD1 2 GO:1905049 negative regulation of metallopeptidase activity 2/313 14/18722 0.0222053097695551 0.127218054945283 TIMP2/TIMP3 2 GO:2001171 positive regulation of ATP biosynthetic process 2/313 14/18722 0.0222053097695551 0.127218054945283 ENO1/TMSB4X 2 GO:0001885 endothelial cell development 4/313 64/18722 0.022222223939746 0.127218054945283 GPX1/TNFRSF1A/CLIC4/EZR 4 GO:0006940 regulation of smooth muscle contraction 4/313 64/18722 0.022222223939746 0.127218054945283 CAV1/ATP2B1/RHOA/RGS2 4 GO:0030104 water homeostasis 4/313 64/18722 0.022222223939746 0.127218054945283 AKR1B1/LSR/CLN3/STMN1 4 GO:0030837 negative regulation of actin filament polymerization 4/313 64/18722 0.022222223939746 0.127218054945283 PFN1/TMSB4X/SCIN/KANK4 4 GO:0032507 maintenance of protein location in cell 4/313 64/18722 0.022222223939746 0.127218054945283 CAV1/TMSB4X/SCIN/GJA1 4 GO:0048857 neural nucleus development 4/313 64/18722 0.022222223939746 0.127218054945283 DYNLL1/RHOA/CALM1/ACTB 4 GO:0080164 regulation of nitric oxide metabolic process 4/313 64/18722 0.022222223939746 0.127218054945283 CAV1/DYNLL1/INSR/CLU 4 GO:0046683 response to organophosphorus 6/313 131/18722 0.0228867385441709 0.130825546002491 LDHA/FOS/JUN/BSG/FOSB/EZR 6 GO:0016032 viral process 13/313 415/18722 0.0229647425153833 0.131074624821685 CAV1/DDX5/LY6E/JUN/BSG/CAV2/CFL1/INSR/ITGB1/HSPA1A/SSB/HACD3/TOP2A 13 GO:0140014 mitotic nuclear division 10/313 287/18722 0.0230497107503859 0.13136264794419 IGF2/NEK6/CCSAP/CAV2/INSR/RHOA/PTTG1/HSPA1A/CDC20/CCNB1 10 GO:0015909 long-chain fatty acid transport 4/313 65/18722 0.0233773090819868 0.132436630468934 PLIN2/ANXA1/SLC27A2/SLC2A1 4 GO:0070613 regulation of protein processing 4/313 65/18722 0.0233773090819868 0.132436630468934 ENO1/SERPINE1/MYH9/CLN3 4 GO:0090307 mitotic spindle assembly 4/313 65/18722 0.0233773090819868 0.132436630468934 CCSAP/RHOA/HSPA1A/CDC20 4 GO:1902475 L-alpha-amino acid transmembrane transport 4/313 65/18722 0.0233773090819868 0.132436630468934 SLC7A5/ITGB1/SLC43A2/RGS2 4 GO:0031098 stress-activated protein kinase signaling cascade 9/313 247/18722 0.0235402797824971 0.132614328363158 PAGE4/GADD45B/PRDX1/EZR/PRMT1/RHOA/AKR1B1/HACD3/MAP3K4 9 GO:0003161 cardiac conduction system development 3/313 37/18722 0.0236517578473594 0.132614328363158 ISL1/GJA1/ID2 3 GO:0021532 neural tube patterning 3/313 37/18722 0.0236517578473594 0.132614328363158 FKBP8/TMEM107/HES1 3 GO:0032570 response to progesterone 3/313 37/18722 0.0236517578473594 0.132614328363158 CAV1/FOS/FOSB 3 GO:0033120 positive regulation of RNA splicing 3/313 37/18722 0.0236517578473594 0.132614328363158 HSPA1A/PRDX6/TRA2B 3 GO:0007569 cell aging 6/313 132/18722 0.0236525161435734 0.132614328363158 NEK6/MIF/SERPINE1/YBX1/PLK2/ID2 6 GO:0035264 multicellular organism growth 6/313 132/18722 0.0236525161435734 0.132614328363158 PLAC8/IGF2/CLIC4/EZR/FKBP8/LGMN 6 GO:0009152 purine ribonucleotide biosynthetic process 7/313 169/18722 0.0237619072038445 0.133031736360347 ALDOA/ENO1/SLC26A2/TMSB4X/PARP1/MPC2/TECR 7 GO:0007409 axonogenesis 13/313 418/18722 0.0241739470016154 0.135139818260132 EFNB1/FN1/NRP2/BSG/S100A6/LAMC2/SEMA6D/ISL1/C12orf57/ITGB1/ACTB/STMN1/B3GNT2 13 GO:0023061 signal release 14/313 463/18722 0.0244209811878075 0.136320638390005 WLS/DYNLL1/ANXA1/CYP19A1/SRI/ISL1/SOX4/SLC16A1/PHPT1/CALM1/MPC2/GJA1/HMGN3/FAM3B 14 GO:0019229 regulation of vasoconstriction 4/313 66/18722 0.0245682290707994 0.1365419679891 CAV1/ATP2B1/RHOA/GJA1 4 GO:0051893 regulation of focal adhesion assembly 4/313 66/18722 0.0245682290707994 0.1365419679891 ACTG1/RHOA/S100A10/PTPRA 4 GO:0090109 regulation of cell-substrate junction assembly 4/313 66/18722 0.0245682290707994 0.1365419679891 ACTG1/RHOA/S100A10/PTPRA 4 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 8/313 209/18722 0.0246580491296672 0.136841389266243 SERPINB9/PMAIP1/GPX1/PDCD6/DHCR24/RHOA/HERPUD1/BIRC5 8 GO:0060485 mesenchyme development 10/313 291/18722 0.025054717279025 0.136993592957078 EFNB1/FN1/DDX5/NRP2/PDCD6/SEMA6D/ISL1/HNRNPAB/TGFBR3/HES1 10 GO:0030833 regulation of actin filament polymerization 7/313 171/18722 0.0251346972339435 0.136993592957078 COTL1/PFN1/RHOA/TMSB4X/SCIN/IQGAP2/KANK4 7 GO:0001508 action potential 6/313 134/18722 0.0252352252092992 0.136993592957078 CAV1/DSP/SRI/CALM1/CLN3/GJA1 6 GO:0032486 Rap protein signal transduction 2/313 15/18722 0.0253424338180328 0.136993592957078 TIMP2/PLK2 2 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway 2/313 15/18722 0.0253424338180328 0.136993592957078 LBH/ISL1 2 GO:0042994 cytoplasmic sequestering of transcription factor 2/313 15/18722 0.0253424338180328 0.136993592957078 SRI/TMSB4X 2 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 2/313 15/18722 0.0253424338180328 0.136993592957078 MIF/PTTG1IP 2 GO:0045176 apical protein localization 2/313 15/18722 0.0253424338180328 0.136993592957078 ACTB/JAM3 2 GO:0045475 locomotor rhythm 2/313 15/18722 0.0253424338180328 0.136993592957078 EGR1/ID2 2 GO:0045725 positive regulation of glycogen biosynthetic process 2/313 15/18722 0.0253424338180328 0.136993592957078 IGF2/INSR 2 GO:0048569 post-embryonic animal organ development 2/313 15/18722 0.0253424338180328 0.136993592957078 LDHA/FBN1 2 GO:0055012 ventricular cardiac muscle cell differentiation 2/313 15/18722 0.0253424338180328 0.136993592957078 FHL2/CCNB1 2 GO:0060413 atrial septum morphogenesis 2/313 15/18722 0.0253424338180328 0.136993592957078 ISL1/SOX4 2 GO:1900029 positive regulation of ruffle assembly 2/313 15/18722 0.0253424338180328 0.136993592957078 EPS8L1/PFN1 2 GO:1901660 calcium ion export 2/313 15/18722 0.0253424338180328 0.136993592957078 ATP2B1/CALM1 2 GO:1905168 positive regulation of double-strand break repair via homologous recombination 2/313 15/18722 0.0253424338180328 0.136993592957078 FUS/PARP1 2 GO:0032717 negative regulation of interleukin-8 production 3/313 38/18722 0.0253691838809404 0.136993592957078 ANXA4/ANXA1/TMSB4X 3 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway 3/313 38/18722 0.0253691838809404 0.136993592957078 LBH/ISL1/RHOA 3 GO:1903580 positive regulation of ATP metabolic process 3/313 38/18722 0.0253691838809404 0.136993592957078 ENO1/INSR/TMSB4X 3 GO:0010632 regulation of epithelial cell migration 10/313 292/18722 0.0255749855042141 0.137909305686321 NRP2/ANXA1/PFN1/PDCD6/RHOA/TMSB4X/HSPB1/RHOB/PLK2/LGMN 10 GO:0061077 chaperone-mediated protein folding 4/313 67/18722 0.0257951949869464 0.138459472821881 HSPA1A/HSPB1/DNAJB4/CLU 4 GO:0061180 mammary gland epithelium development 4/313 67/18722 0.0257951949869464 0.138459472821881 LBH/GPX1/CEBPB/ID2 4 GO:0001678 cellular glucose homeostasis 7/313 172/18722 0.0258410694550412 0.138459472821881 DYNLL1/SRI/SOX4/PHPT1/MPC2/HMGN3/TRA2B 7 GO:0042770 signal transduction in response to DNA damage 7/313 172/18722 0.0258410694550412 0.138459472821881 DDX5/PMAIP1/MIF/PTTG1IP/SOX4/PPP1R10/PLK2 7 GO:0006816 calcium ion transport 13/313 422/18722 0.0258588613544412 0.138459472821881 CAV1/C4orf3/GSTO1/ATP2B1/SRI/RHOA/PDE4B/TMBIM6/SARAF/CALM1/GJA1/AHNAK/MCOLN3 13 GO:0001101 response to acid chemical 6/313 135/18722 0.0260524333031133 0.139300019079989 KRT8/RHOA/CEBPB/AKR1B1/TMBIM6/DNMT3A 6 GO:0006417 regulation of translation 14/313 468/18722 0.0264393346899289 0.14117047288157 GAPDH/PKM/RPL38/EIF4H/YBX3/SOX4/RHOA/EIF4B/HSPB1/YBX1/EIF5A/BTG2/PPP1R15A/RGS2 14 GO:0043523 regulation of neuron apoptotic process 8/313 212/18722 0.0265492870522655 0.141559013736659 JUN/ISL1/RHOA/CEBPB/PARP1/BTG2/CLN3/LGMN 8 GO:0043624 cellular protein complex disassembly 6/313 136/18722 0.0268870555717438 0.142787298090113 STMN3/CCSAP/CFL1/SCIN/EIF5A/STMN1 6 GO:0045727 positive regulation of translation 6/313 136/18722 0.0268870555717438 0.142787298090113 PKM/YBX3/SOX4/RHOA/EIF5A/PPP1R15A 6 GO:0060828 regulation of canonical Wnt signaling pathway 9/313 253/18722 0.0269296769184925 0.142787298090113 CAV1/WLS/TLE4/ISL1/SOX4/LGR5/CTNND1/EGR1/FERMT1 9 GO:0097305 response to alcohol 9/313 253/18722 0.0269296769184925 0.142787298090113 FOS/ATP2B1/FOSB/RHOA/PARP1/CALM1/TGFBR3/DNMT3A/RGS2 9 GO:0009206 purine ribonucleoside triphosphate biosynthetic process 4/313 68/18722 0.0270583989024025 0.143071284196453 ALDOA/ENO1/TMSB4X/PARP1 4 GO:0032922 circadian regulation of gene expression 4/313 68/18722 0.0270583989024025 0.143071284196453 MAGED1/BHLHE41/EGR1/ID2 4 GO:0051154 negative regulation of striated muscle cell differentiation 3/313 39/18722 0.0271519443321861 0.143168216167081 YBX1/BHLHE41/RGS2 3 GO:0086091 regulation of heart rate by cardiac conduction 3/313 39/18722 0.0271519443321861 0.143168216167081 CAV1/DSP/ISL1 3 GO:0001659 temperature homeostasis 7/313 174/18722 0.0272942906365054 0.143323261314725 PLAC8/CAV1/GPX1/CEBPB/GJA1/ARRDC3/EGR1 7 GO:0007584 response to nutrient 7/313 174/18722 0.0272942906365054 0.143323261314725 LDHA/STC2/ATP2B1/SLC16A1/COX4I1/AGL/DNMT3A 7 GO:0048639 positive regulation of developmental growth 7/313 174/18722 0.0272942906365054 0.143323261314725 IGF2/FN1/YBX3/EZR/INSR/TGFBR3/CCNB1 7 GO:0001655 urogenital system development 11/313 338/18722 0.0274196516508815 0.143783214648631 FBN1/ANXA1/ADAMTS6/SOX4/MAGED1/RHOA/AKR1B1/LGR5/EGR1/ADAMTS1/HES1 11 GO:0032535 regulation of cellular component size 12/313 382/18722 0.0277071914664569 0.144464043246676 FN1/COTL1/PFN1/SEMA6D/EZR/RHOA/TMSB4X/SCIN/CLN3/PPP1R15A/IQGAP2/KANK4 12 GO:0050890 cognition 10/313 296/18722 0.0277338161432741 0.144464043246676 FOS/JUN/C12orf57/INSR/CEBPB/ITGB1/BTG2/CLN3/PLK2/LGMN 10 GO:0051258 protein polymerization 10/313 296/18722 0.0277338161432741 0.144464043246676 COTL1/PFN1/GPX4/RHOA/TMSB4X/SCIN/HSPA1A/STMN1/IQGAP2/KANK4 10 GO:0006986 response to unfolded protein 6/313 137/18722 0.0277392213326294 0.144464043246676 HERPUD1/HSPA1A/HSPB1/TMBIM6/PPP1R15A/DNAJB4 6 GO:0090090 negative regulation of canonical Wnt signaling pathway 6/313 137/18722 0.0277392213326294 0.144464043246676 CAV1/TLE4/ISL1/CTNND1/EGR1/FERMT1 6 GO:0022900 electron transport chain 7/313 175/18722 0.0280413426487231 0.145416023820164 DHRS2/CYP19A1/UQCRB/COX4I1/AKR1B1/NDUFB1/CCNB1 7 GO:1905475 regulation of protein localization to membrane 7/313 175/18722 0.0280413426487231 0.145416023820164 TCAF1/EZR/TMBIM1/ITGB1/ACTB/CLN3/NMT1 7 GO:0031331 positive regulation of cellular catabolic process 13/313 427/18722 0.0280849379444904 0.145416023820164 CAV1/PTTG1IP/DDA1/EZR/INSR/CTSC/HERPUD1/HSPA1A/BTG2/CDC20/KCNQ1OT1/CLU/PLK2 13 GO:0007611 learning or memory 9/313 255/18722 0.0281323411064806 0.145416023820164 FOS/JUN/INSR/CEBPB/ITGB1/BTG2/CLN3/PLK2/LGMN 9 GO:0010522 regulation of calcium ion transport into cytosol 5/313 102/18722 0.0283255260461355 0.145416023820164 CAV1/GSTO1/SRI/TMBIM6/CALM1 5 GO:0032677 regulation of interleukin-8 production 5/313 102/18722 0.0283255260461355 0.145416023820164 ANXA4/ANXA1/SERPINE1/TMSB4X/HSPA1A 5 GO:0009145 purine nucleoside triphosphate biosynthetic process 4/313 69/18722 0.0283580140448549 0.145416023820164 ALDOA/ENO1/TMSB4X/PARP1 4 GO:0010611 regulation of cardiac muscle hypertrophy 4/313 69/18722 0.0283580140448549 0.145416023820164 TNFRSF1A/PARP1/ERRFI1/RGS2 4 GO:0015807 L-amino acid transport 4/313 69/18722 0.0283580140448549 0.145416023820164 SLC7A5/SERINC5/ITGB1/SLC43A2 4 GO:0002693 positive regulation of cellular extravasation 2/313 16/18722 0.0286477588298196 0.145416023820164 CD99/JAM3 2 GO:0005980 glycogen catabolic process 2/313 16/18722 0.0286477588298196 0.145416023820164 PYGL/AGL 2 GO:0006349 regulation of gene expression by genetic imprinting 2/313 16/18722 0.0286477588298196 0.145416023820164 IGF2/DNMT3A 2 GO:0006857 oligopeptide transport 2/313 16/18722 0.0286477588298196 0.145416023820164 SLC13A3/GJA1 2 GO:0009415 response to water 2/313 16/18722 0.0286477588298196 0.145416023820164 KRT8/AKR1B1 2 GO:0014819 regulation of skeletal muscle contraction 2/313 16/18722 0.0286477588298196 0.145416023820164 GSTO1/C12orf57 2 GO:0021783 preganglionic parasympathetic fiber development 2/313 16/18722 0.0286477588298196 0.145416023820164 NRP2/HES1 2 GO:0070365 hepatocyte differentiation 2/313 16/18722 0.0286477588298196 0.145416023820164 KRT18/ANXA1 2 GO:0099010 modification of postsynaptic structure 2/313 16/18722 0.0286477588298196 0.145416023820164 PFN1/RHOA 2 GO:2000765 regulation of cytoplasmic translation 2/313 16/18722 0.0286477588298196 0.145416023820164 PKM/YBX3 2 GO:0045777 positive regulation of blood pressure 3/313 40/18722 0.0289998905834518 0.146337833079486 RHOA/TPM1/ID2 3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 3/313 40/18722 0.0289998905834518 0.146337833079486 GSTO1/SRI/CALM1 3 GO:0060412 ventricular septum morphogenesis 3/313 40/18722 0.0289998905834518 0.146337833079486 SOX4/TGFBR3/HES1 3 GO:0070266 necroptotic process 3/313 40/18722 0.0289998905834518 0.146337833079486 CAV1/PYGL/YBX3 3 GO:0031667 response to nutrient levels 14/313 474/18722 0.0290215560743399 0.146337833079486 LDHA/PAGE4/KRT18/STC2/PMAIP1/MBD3/ATP2B1/JUN/SLC16A1/COX4I1/AGL/STK24/SLC2A1/DNMT3A 14 GO:0042326 negative regulation of phosphorylation 12/313 385/18722 0.0291814613147366 0.146949501620638 CAV1/IGFBP3/DYNLL1/MLLT1/GADD45B/FBLN1/FKBP8/HSPB1/CALM1/ERRFI1/CCNB1/RGS2 12 GO:0032637 interleukin-8 production 5/313 103/18722 0.0293788257010706 0.147747938499307 ANXA4/ANXA1/SERPINE1/TMSB4X/HSPA1A 5 GO:0001933 negative regulation of protein phosphorylation 11/313 342/18722 0.0295207728461821 0.148265939611366 CAV1/IGFBP3/MLLT1/GADD45B/FBLN1/FKBP8/HSPB1/CALM1/ERRFI1/CCNB1/RGS2 11 GO:0002548 monocyte chemotaxis 4/313 70/18722 0.0296941949759806 0.148940448318259 ANXA1/SERPINE1/FLT1/LGMN 4 GO:0008154 actin polymerization or depolymerization 8/313 217/18722 0.0299217922803957 0.149884556857193 COTL1/PFN1/CFL1/RHOA/TMSB4X/SCIN/IQGAP2/KANK4 8 GO:0035265 organ growth 7/313 178/18722 0.030365440305621 0.151907005576215 IGF2/LY6E/YBX3/GJA1/TGFBR3/CCNB1/RGS2 7 GO:0048661 positive regulation of smooth muscle cell proliferation 5/313 104/18722 0.0304565549827677 0.151963440130271 JUN/AKR1B1/GJA1/ADAMTS1/ID2 5 GO:1903076 regulation of protein localization to plasma membrane 5/313 104/18722 0.0304565549827677 0.151963440130271 EZR/TMBIM1/ITGB1/ACTB/CLN3 5 GO:0030336 negative regulation of cell migration 11/313 344/18722 0.0306135685932708 0.152429640343773 IGFBP3/MIF/TCAF1/SERPINE1/SEMA6D/CLIC4/RHOA/STK24/TPM1/GJA1/RHOB 11 GO:0042445 hormone metabolic process 8/313 218/18722 0.0306300695726259 0.152429640343773 RDH13/DHRS2/CYP11A1/STC2/CYP19A1/HSD17B1/AKR1B1/EGR1 8 GO:0010907 positive regulation of glucose metabolic process 3/313 41/18722 0.0309128193540812 0.153036545228852 IGF2/PMAIP1/INSR 3 GO:0070296 sarcoplasmic reticulum calcium ion transport 3/313 41/18722 0.0309128193540812 0.153036545228852 GSTO1/SRI/CALM1 3 GO:0071634 regulation of transforming growth factor beta production 3/313 41/18722 0.0309128193540812 0.153036545228852 FN1/ITGB8/FERMT1 3 GO:1900371 regulation of purine nucleotide biosynthetic process 3/313 41/18722 0.0309128193540812 0.153036545228852 ENO1/TMSB4X/PARP1 3 GO:0003281 ventricular septum development 4/313 71/18722 0.031067077782654 0.15340125177505 LMO4/SOX4/TGFBR3/HES1 4 GO:0150116 regulation of cell-substrate junction organization 4/313 71/18722 0.031067077782654 0.15340125177505 ACTG1/RHOA/S100A10/PTPRA 4 GO:0072001 renal system development 10/313 302/18722 0.0312113347752428 0.153913926799675 FBN1/ADAMTS6/SOX4/MAGED1/RHOA/AKR1B1/LGR5/EGR1/ADAMTS1/HES1 10 GO:0032355 response to estradiol 6/313 141/18722 0.031325776009105 0.153998221567364 ANXA1/MBD3/CYP19A1/GPX4/GJA1/DNMT3A 6 GO:0050921 positive regulation of chemotaxis 6/313 141/18722 0.031325776009105 0.153998221567364 SERPINE1/VEGFB/PGF/TMSB4X/HSPB1/LGMN 6 GO:2001020 regulation of response to DNA damage stimulus 8/313 219/18722 0.0313497824309711 0.153998221567364 DDX5/PMAIP1/MIF/PTTG1IP/FUS/PPP1R10/PARP1/CLU 8 GO:0040029 regulation of gene expression, epigenetic 5/313 105/18722 0.0315588512591557 0.154825446834543 IGF2/MBD3/GPX1/SERTAD1/DNMT3A 5 GO:0006631 fatty acid metabolic process 12/313 390/18722 0.0317636253210539 0.155350860722456 CYP2J2/CROT/CAV1/ANXA1/GPX1/MIF/SLC27A2/TNFRSF1A/GPX4/AKR1B1/TECR/HACD3 12 GO:0009251 glucan catabolic process 2/313 17/18722 0.0321148220090815 0.155350860722456 PYGL/AGL 2 GO:0016264 gap junction assembly 2/313 17/18722 0.0321148220090815 0.155350860722456 CAV1/GJA1 2 GO:0033623 regulation of integrin activation 2/313 17/18722 0.0321148220090815 0.155350860722456 JAM3/FERMT1 2 GO:0044539 long-chain fatty acid import into cell 2/313 17/18722 0.0321148220090815 0.155350860722456 SLC27A2/SLC2A1 2 GO:0055119 relaxation of cardiac muscle 2/313 17/18722 0.0321148220090815 0.155350860722456 PDE4B/RGS2 2 GO:0070875 positive regulation of glycogen metabolic process 2/313 17/18722 0.0321148220090815 0.155350860722456 IGF2/INSR 2 GO:0090083 regulation of inclusion body assembly 2/313 17/18722 0.0321148220090815 0.155350860722456 HSPA1A/CLU 2 GO:0140354 lipid import into cell 2/313 17/18722 0.0321148220090815 0.155350860722456 SLC27A2/SLC2A1 2 GO:1902358 sulfate transmembrane transport 2/313 17/18722 0.0321148220090815 0.155350860722456 SLC26A2/SLC13A4 2 GO:2000811 negative regulation of anoikis 2/313 17/18722 0.0321148220090815 0.155350860722456 CAV1/ITGB1 2 GO:0014743 regulation of muscle hypertrophy 4/313 72/18722 0.0324767802802651 0.156703551998693 TNFRSF1A/PARP1/ERRFI1/RGS2 4 GO:0055021 regulation of cardiac muscle tissue growth 4/313 72/18722 0.0324767802802651 0.156703551998693 GJA1/TGFBR3/CCNB1/RGS2 4 GO:0035821 modulation of process of other organism 5/313 106/18722 0.0326858441891035 0.157313538341235 SERPINB9/JUN/CAV2/CFL1/INSR 5 GO:1905477 positive regulation of protein localization to membrane 5/313 106/18722 0.0326858441891035 0.157313538341235 TCAF1/EZR/ITGB1/CLN3/NMT1 5 GO:0030808 regulation of nucleotide biosynthetic process 3/313 42/18722 0.0328904752367957 0.157899166742095 ENO1/TMSB4X/PARP1 3 GO:0035019 somatic stem cell population maintenance 3/313 42/18722 0.0328904752367957 0.157899166742095 LBH/SOX4/HES1 3 GO:0045785 positive regulation of cell adhesion 13/313 437/18722 0.0329532270313862 0.158001177970387 IGF2/CAV1/EFNB1/PLEKHA2/FN1/ANXA1/CCDC80/SOX4/RHOA/S100A10/TPM1/FERMT1/HES1 13 GO:0062013 positive regulation of small molecule metabolic process 6/313 143/18722 0.0332274023516908 0.15911537201621 IGF2/ANXA1/ENO1/PMAIP1/INSR/TMSB4X 6 GO:0009260 ribonucleotide biosynthetic process 7/313 182/18722 0.0336612315224827 0.160788341789324 ALDOA/ENO1/SLC26A2/TMSB4X/PARP1/MPC2/TECR 7 GO:0060401 cytosolic calcium ion transport 7/313 182/18722 0.0336612315224827 0.160788341789324 CAV1/GSTO1/ATP2B1/SRI/TMBIM6/CALM1/MCOLN3 7 GO:0046718 viral entry into host cell 6/313 144/18722 0.0342056794177332 0.163184237522945 CAV1/LY6E/BSG/CAV2/ITGB1/HSPA1A 6 GO:0006509 membrane protein ectodomain proteolysis 3/313 43/18722 0.0349325531540194 0.165202770009133 TIMP2/TIMP3/MYH9 3 GO:0031952 regulation of protein autophosphorylation 3/313 43/18722 0.0349325531540194 0.165202770009133 CAV1/CALM1/ERRFI1 3 GO:0042181 ketone biosynthetic process 3/313 43/18722 0.0349325531540194 0.165202770009133 TPI1/HSD17B1/EGR1 3 GO:0045981 positive regulation of nucleotide metabolic process 3/313 43/18722 0.0349325531540194 0.165202770009133 ENO1/INSR/TMSB4X 3 GO:0071604 transforming growth factor beta production 3/313 43/18722 0.0349325531540194 0.165202770009133 FN1/ITGB8/FERMT1 3 GO:1900544 positive regulation of purine nucleotide metabolic process 3/313 43/18722 0.0349325531540194 0.165202770009133 ENO1/INSR/TMSB4X 3 GO:1903793 positive regulation of anion transport 3/313 43/18722 0.0349325531540194 0.165202770009133 TCAF1/CEBPB/ITGB1 3 GO:0043524 negative regulation of neuron apoptotic process 6/313 145/18722 0.035202398845062 0.16611966952112 ISL1/RHOA/CEBPB/BTG2/CLN3/LGMN 6 GO:0003151 outflow tract morphogenesis 4/313 74/18722 0.0354070255508797 0.16611966952112 NRP2/ISL1/TGFBR3/HES1 4 GO:0009201 ribonucleoside triphosphate biosynthetic process 4/313 74/18722 0.0354070255508797 0.16611966952112 ALDOA/ENO1/TMSB4X/PARP1 4 GO:0120192 tight junction assembly 4/313 74/18722 0.0354070255508797 0.16611966952112 ACTG1/LSR/GJA1/CLDN7 4 GO:1903201 regulation of oxidative stress-induced cell death 4/313 74/18722 0.0354070255508797 0.16611966952112 PAGE4/GPX1/HSPB1/PARP1 4 GO:0008272 sulfate transport 2/313 18/18722 0.0357373284312575 0.16611966952112 SLC26A2/SLC13A4 2 GO:0030728 ovulation 2/313 18/18722 0.0357373284312575 0.16611966952112 ADAMTS1/RGS2 2 GO:0043217 myelin maintenance 2/313 18/18722 0.0357373284312575 0.16611966952112 EPB41L3/CLU 2 GO:0044247 cellular polysaccharide catabolic process 2/313 18/18722 0.0357373284312575 0.16611966952112 PYGL/AGL 2 GO:0048486 parasympathetic nervous system development 2/313 18/18722 0.0357373284312575 0.16611966952112 NRP2/HES1 2 GO:0060192 negative regulation of lipase activity 2/313 18/18722 0.0357373284312575 0.16611966952112 ANXA1/RGS2 2 GO:0060546 negative regulation of necroptotic process 2/313 18/18722 0.0357373284312575 0.16611966952112 CAV1/YBX3 2 GO:1901673 regulation of mitotic spindle assembly 2/313 18/18722 0.0357373284312575 0.16611966952112 CCSAP/HSPA1A 2 GO:2000136 regulation of cell proliferation involved in heart morphogenesis 2/313 18/18722 0.0357373284312575 0.16611966952112 ISL1/HES1 2 GO:0016485 protein processing 8/313 225/18722 0.035912211953398 0.166729013300715 ENO1/SERPINE1/PGK1/DHCR24/MYH9/PARP1/CLN3/LGMN 8 GO:0022411 cellular component disassembly 13/313 443/18722 0.0361516606125362 0.167128017682254 NEK6/STMN3/RPL23/CCSAP/CFL1/INSR/UBA5/SCIN/CALM1/EIF5A/CLN3/STMN1/TOP2A 13 GO:0006821 chloride transport 5/313 109/18722 0.0362161836467731 0.167128017682254 FXYD3/CLIC3/CLIC4/SLC26A2/CLIC1 5 GO:0032410 negative regulation of transporter activity 5/313 109/18722 0.0362161836467731 0.167128017682254 CAV1/C4orf3/GSTO1/SRI/CALM1 5 GO:0010675 regulation of cellular carbohydrate metabolic process 6/313 146/18722 0.0362176555260992 0.167128017682254 IGF2/PMAIP1/PHLDA2/PGAM1/INSR/PGP 6 GO:0042542 response to hydrogen peroxide 6/313 146/18722 0.0362176555260992 0.167128017682254 LDHA/ANXA1/GPX1/JUN/STK24/RHOB 6 GO:0002040 sprouting angiogenesis 7/313 185/18722 0.0362838604103716 0.167230819106882 PKM/ANXA1/VEGFB/PGF/RHOA/ITGB1/PLK2 7 GO:0043627 response to estrogen 4/313 75/18722 0.0369277145811692 0.169682712037283 KRT19/LDHA/SERPINB9/CAV1 4 GO:1902369 negative regulation of RNA catabolic process 4/313 75/18722 0.0369277145811692 0.169682712037283 YBX3/FUS/PKP3/YBX1 4 GO:0021517 ventral spinal cord development 3/313 44/18722 0.0370387007362706 0.169682712037283 LMO4/ISL1/SOX4 3 GO:0032881 regulation of polysaccharide metabolic process 3/313 44/18722 0.0370387007362706 0.169682712037283 IGF2/PHLDA2/INSR 3 GO:0097178 ruffle assembly 3/313 44/18722 0.0370387007362706 0.169682712037283 CAV1/EPS8L1/PFN1 3 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 7/313 186/18722 0.0371872217211086 0.170158357082044 GAPDH/NEK6/WLS/TNFRSF1A/RHOA/GJA1/PLK2 7 GO:0001889 liver development 6/313 147/18722 0.0372515403789166 0.170248036281555 KRT18/ANXA1/CEBPB/LSR/TGFBR3/HES1 6 GO:0003014 renal system process 5/313 110/18722 0.037443105302105 0.170305737019252 RHOA/AKR1B1/CLN3/GJA1/LGMN 5 GO:0032611 interleukin-1 beta production 5/313 110/18722 0.037443105302105 0.170305737019252 SERPINB1/ISL1/HSPB1/ERRFI1/EGR1 5 GO:0032651 regulation of interleukin-1 beta production 5/313 110/18722 0.037443105302105 0.170305737019252 SERPINB1/ISL1/HSPB1/ERRFI1/EGR1 5 GO:0048259 regulation of receptor-mediated endocytosis 5/313 110/18722 0.037443105302105 0.170305737019252 CD63/SERPINE1/AAK1/INSR/CLU 5 GO:0046777 protein autophosphorylation 8/313 227/18722 0.0375276668374697 0.17048666784039 CAV1/NEK6/AAK1/INSR/STK24/FLT1/CALM1/ERRFI1 8 GO:0008064 regulation of actin polymerization or depolymerization 7/313 187/18722 0.0381052849090255 0.172572862826543 COTL1/PFN1/RHOA/TMSB4X/SCIN/IQGAP2/KANK4 7 GO:0033044 regulation of chromosome organization 7/313 187/18722 0.0381052849090255 0.172572862826543 NEK6/PTTG1/PPP1R10/PARP1/MAP3K4/TOP2A/CCNB1 7 GO:0010212 response to ionizing radiation 6/313 148/18722 0.0383041403251627 0.172572862826543 ANXA1/GPX1/PARP1/EGR1/RHOB/DNMT3A 6 GO:0014074 response to purine-containing compound 6/313 148/18722 0.0383041403251627 0.172572862826543 LDHA/FOS/JUN/BSG/FOSB/EZR 6 GO:0097530 granulocyte migration 6/313 148/18722 0.0383041403251627 0.172572862826543 ANXA1/CD99/BSG/CSF3R/PDE4B/JAM3 6 GO:0001937 negative regulation of endothelial cell proliferation 4/313 76/18722 0.0384855162962267 0.172572862826543 CAV1/CAV2/FLT1/GJA1 4 GO:0006305 DNA alkylation 4/313 76/18722 0.0384855162962267 0.172572862826543 MBD3/FOS/PARP1/DNMT3A 4 GO:0006306 DNA methylation 4/313 76/18722 0.0384855162962267 0.172572862826543 MBD3/FOS/PARP1/DNMT3A 4 GO:0006809 nitric oxide biosynthetic process 4/313 76/18722 0.0384855162962267 0.172572862826543 CAV1/DYNLL1/INSR/CLU 4 GO:0043536 positive regulation of blood vessel endothelial cell migration 4/313 76/18722 0.0384855162962267 0.172572862826543 ANXA1/TMSB4X/HSPB1/PLK2 4 GO:0086001 cardiac muscle cell action potential 4/313 76/18722 0.0384855162962267 0.172572862826543 CAV1/DSP/CALM1/GJA1 4 GO:0030832 regulation of actin filament length 7/313 188/18722 0.0390381221157508 0.174491094711489 COTL1/PFN1/RHOA/TMSB4X/SCIN/IQGAP2/KANK4 7 GO:0045444 fat cell differentiation 8/313 229/18722 0.0391913006381462 0.174491094711489 PLAC8/GPX1/ADIRF/CEBPB/ARL4A/ID2/RGS2/HES1 8 GO:1904646 cellular response to amyloid-beta 3/313 45/18722 0.039208520624699 0.174491094711489 PARP1/GJA1/LGMN 3 GO:0006071 glycerol metabolic process 2/313 19/18722 0.0395091472659059 0.174491094711489 TPI1/PGP 2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 2/313 19/18722 0.0395091472659059 0.174491094711489 SOX4/PLK2 2 GO:0033194 response to hydroperoxide 2/313 19/18722 0.0395091472659059 0.174491094711489 GPX3/GPX1 2 GO:0044003 modulation by symbiont of host process 2/313 19/18722 0.0395091472659059 0.174491094711489 SERPINB9/INSR 2 GO:0045019 negative regulation of nitric oxide biosynthetic process 2/313 19/18722 0.0395091472659059 0.174491094711489 CAV1/DYNLL1 2 GO:0046794 transport of virus 2/313 19/18722 0.0395091472659059 0.174491094711489 CAV1/CAV2 2 GO:0060216 definitive hemopoiesis 2/313 19/18722 0.0395091472659059 0.174491094711489 MFAP5/TGFBR3 2 GO:0061323 cell proliferation involved in heart morphogenesis 2/313 19/18722 0.0395091472659059 0.174491094711489 ISL1/HES1 2 GO:0062099 negative regulation of programmed necrotic cell death 2/313 19/18722 0.0395091472659059 0.174491094711489 CAV1/YBX3 2 GO:1904406 negative regulation of nitric oxide metabolic process 2/313 19/18722 0.0395091472659059 0.174491094711489 CAV1/DYNLL1 2 GO:0009141 nucleoside triphosphate metabolic process 5/313 112/18722 0.0399727192097761 0.176129794018076 ALDOA/ENO1/RHOA/TMSB4X/PARP1 5 GO:0048640 negative regulation of developmental growth 5/313 112/18722 0.0399727192097761 0.176129794018076 PLAC8/SEMA6D/GJA1/LGMN/RGS2 5 GO:0061008 hepaticobiliary system development 6/313 150/18722 0.0404658130844399 0.178096358858338 KRT18/ANXA1/CEBPB/LSR/TGFBR3/HES1 6 GO:0030041 actin filament polymerization 7/313 190/18722 0.0409483953934117 0.180012172358797 COTL1/PFN1/RHOA/TMSB4X/SCIN/IQGAP2/KANK4 7 GO:0031623 receptor internalization 5/313 113/18722 0.0412755704531865 0.181134405589127 CAV1/CD63/EZR/INSR/ITGB1 5 GO:0007019 microtubule depolymerization 3/313 46/18722 0.0414415726997976 0.181134405589127 STMN3/CCSAP/STMN1 3 GO:0031018 endocrine pancreas development 3/313 46/18722 0.0414415726997976 0.181134405589127 ANXA1/SOX4/HES1 3 GO:0050919 negative chemotaxis 3/313 46/18722 0.0414415726997976 0.181134405589127 NRP2/SEMA6D/RHOA 3 GO:0060976 coronary vasculature development 3/313 46/18722 0.0414415726997976 0.181134405589127 VEGFB/ADAMTS6/TGFBR3 3 GO:0044409 entry into host 6/313 151/18722 0.0415750395888181 0.181485391600981 CAV1/LY6E/BSG/CAV2/ITGB1/HSPA1A 6 GO:0019319 hexose biosynthetic process 4/313 78/18722 0.0417125604546514 0.181485391600981 TPI1/PGK1/AKR1B1/PGP 4 GO:0070373 negative regulation of ERK1 and ERK2 cascade 4/313 78/18722 0.0417125604546514 0.181485391600981 TIMP3/FBLN1/EZR/ERRFI1 4 GO:0090559 regulation of membrane permeability 4/313 78/18722 0.0417125604546514 0.181485391600981 PMAIP1/HSPA1A/NMT1/JAM3 4 GO:0006402 mRNA catabolic process 8/313 232/18722 0.0417781278876853 0.181563165374907 DDX5/YBX3/FUS/PKP3/HSPA1A/YBX1/SSB/BTG2 8 GO:0006164 purine nucleotide biosynthetic process 7/313 191/18722 0.0419259639339989 0.181997884488864 ALDOA/ENO1/SLC26A2/TMSB4X/PARP1/MPC2/TECR 7 GO:0002244 hematopoietic progenitor cell differentiation 5/313 114/18722 0.0426038777625327 0.184310184820411 SOX4/FLT1/JAM3/TOP2A/HES1 5 GO:0051261 protein depolymerization 5/313 114/18722 0.0426038777625327 0.184310184820411 STMN3/CCSAP/CFL1/SCIN/STMN1 5 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 5/313 114/18722 0.0426038777625327 0.184310184820411 FKBP8/PARP1/TGFBR3/FERMT1/HES1 5 GO:0008202 steroid metabolic process 10/313 319/18722 0.042712592987551 0.184570762206137 DHRS2/CYP11A1/CYP19A1/HSD17B1/SLC27A2/DHCR24/AKR1B1/CYB5R1/EGR1/LGMN 10 GO:0006446 regulation of translational initiation 4/313 79/18722 0.0433818124047427 0.184710995367627 EIF4H/EIF4B/HSPB1/PPP1R15A 4 GO:0060420 regulation of heart growth 4/313 79/18722 0.0433818124047427 0.184710995367627 GJA1/TGFBR3/CCNB1/RGS2 4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle 2/313 20/18722 0.0434243080782837 0.184710995367627 BACH1/ID2 2 GO:0000272 polysaccharide catabolic process 2/313 20/18722 0.0434243080782837 0.184710995367627 PYGL/AGL 2 GO:0003159 morphogenesis of an endothelium 2/313 20/18722 0.0434243080782837 0.184710995367627 RHOA/RHOB 2 GO:0003215 cardiac right ventricle morphogenesis 2/313 20/18722 0.0434243080782837 0.184710995367627 ISL1/SOX4 2 GO:0006346 DNA methylation-dependent heterochromatin assembly 2/313 20/18722 0.0434243080782837 0.184710995367627 MBD3/DNMT3A 2 GO:0042359 vitamin D metabolic process 2/313 20/18722 0.0434243080782837 0.184710995367627 CYP11A1/LGMN 2 GO:0043011 myeloid dendritic cell differentiation 2/313 20/18722 0.0434243080782837 0.184710995367627 DHRS2/ITGB8 2 GO:0061154 endothelial tube morphogenesis 2/313 20/18722 0.0434243080782837 0.184710995367627 RHOA/RHOB 2 GO:0090201 negative regulation of release of cytochrome c from mitochondria 2/313 20/18722 0.0434243080782837 0.184710995367627 GPX1/CLU 2 GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 2/313 20/18722 0.0434243080782837 0.184710995367627 GPX1/HSPB1 2 GO:1904292 regulation of ERAD pathway 2/313 20/18722 0.0434243080782837 0.184710995367627 CAV1/HERPUD1 2 GO:2000678 negative regulation of transcription regulatory region DNA binding 2/313 20/18722 0.0434243080782837 0.184710995367627 SRI/TMSB4X 2 GO:0042311 vasodilation 3/313 47/18722 0.0437373762382693 0.185214895816564 GPX1/GJA1/RGS2 3 GO:0072583 clathrin-dependent endocytosis 3/313 47/18722 0.0437373762382693 0.185214895816564 AAK1/CLTB/AP2A2 3 GO:0097028 dendritic cell differentiation 3/313 47/18722 0.0437373762382693 0.185214895816564 DHRS2/CEBPB/ITGB8 3 GO:0097300 programmed necrotic cell death 3/313 47/18722 0.0437373762382693 0.185214895816564 CAV1/PYGL/YBX3 3 GO:0006401 RNA catabolic process 9/313 278/18722 0.0447644311096211 0.189353543593697 DDX5/YBX3/FUS/PKP3/HSPA1A/YBX1/SSB/BTG2/KCNQ1OT1 9 GO:0030856 regulation of epithelial cell differentiation 6/313 154/18722 0.0450171164133471 0.190211056809781 CAV1/TNFRSF1A/SERPINE1/CEBPB/ERRFI1/HES1 6 GO:0009615 response to virus 11/313 367/18722 0.0453217562269029 0.191285948953237 HTRA1/ENO1/PMAIP1/CFL1/SERINC5/HSPB1/EIF5A/ITGB8/STMN1/CLU/EXOC1 11 GO:0033628 regulation of cell adhesion mediated by integrin 3/313 48/18722 0.0460954119999823 0.19347875797567 SERPINE1/JAM3/FERMT1 3 GO:0035036 sperm-egg recognition 3/313 48/18722 0.0460954119999823 0.19347875797567 ALDOA/LY6K/SPESP1 3 GO:0042908 xenobiotic transport 3/313 48/18722 0.0460954119999823 0.19347875797567 SLC7A5/GJA1/SLC2A1 3 GO:0090199 regulation of release of cytochrome c from mitochondria 3/313 48/18722 0.0460954119999823 0.19347875797567 PMAIP1/GPX1/CLU 3 GO:1905710 positive regulation of membrane permeability 3/313 48/18722 0.0460954119999823 0.19347875797567 HSPA1A/NMT1/JAM3 3 GO:0006665 sphingolipid metabolic process 6/313 155/18722 0.046202816429885 0.193502884651895 ORMDL1/SERINC5/TECR/HACD3/SPTSSA/ITGB8 6 GO:0051147 regulation of muscle cell differentiation 6/313 155/18722 0.046202816429885 0.193502884651895 IGF2/MORF4L2/YBX1/BHLHE41/ID2/RGS2 6 GO:0031334 positive regulation of protein-containing complex assembly 8/313 237/18722 0.0463368406803476 0.193850936780311 PFN1/ICE1/RHOA/SCIN/HSPA1A/IQGAP2/CLU/FERMT1 8 GO:0014902 myotube differentiation 5/313 117/18722 0.0467421015931382 0.194558588128328 ADAM12/GPX1/CAV2/MYH9/BHLHE41 5 GO:0051225 spindle assembly 5/313 117/18722 0.0467421015931382 0.194558588128328 NEK6/CCSAP/RHOA/HSPA1A/CDC20 5 GO:0046209 nitric oxide metabolic process 4/313 81/18722 0.0468316771792767 0.194558588128328 CAV1/DYNLL1/INSR/CLU 4 GO:0071260 cellular response to mechanical stimulus 4/313 81/18722 0.0468316771792767 0.194558588128328 TNFRSF1A/GJA1/TMEM150C/SLC2A1 4 GO:2001021 negative regulation of response to DNA damage stimulus 4/313 81/18722 0.0468316771792767 0.194558588128328 MIF/PTTG1IP/PPP1R10/CLU 4 GO:0045664 regulation of neuron differentiation 7/313 196/18722 0.0470405584388738 0.194558588128328 TIMP2/ISL1/NREP/RHOA/HMG20B/ID2/HES1 7 GO:0007249 I-kappaB kinase/NF-kappaB signaling 9/313 281/18722 0.0473334874561735 0.194558588128328 GAPDH/NEK6/WLS/TNFRSF1A/RHOA/HSPB1/GJA1/HACD3/PLK2 9 GO:0060562 epithelial tube morphogenesis 10/313 325/18722 0.0473838642340688 0.194558588128328 LMO4/PFN1/SOX4/CLIC4/MAGED1/RHOA/LGR5/RHOB/HES1/BRD2 10 GO:0032516 positive regulation of phosphoprotein phosphatase activity 2/313 21/18722 0.0474769972080947 0.194558588128328 CALM1/PPP1R15A 2 GO:0044342 type B pancreatic cell proliferation 2/313 21/18722 0.0474769972080947 0.194558588128328 SERPINB1/ERRFI1 2 GO:0044766 multi-organism transport 2/313 21/18722 0.0474769972080947 0.194558588128328 CAV1/CAV2 2 GO:0046885 regulation of hormone biosynthetic process 2/313 21/18722 0.0474769972080947 0.194558588128328 STC2/EGR1 2 GO:0048485 sympathetic nervous system development 2/313 21/18722 0.0474769972080947 0.194558588128328 NRP2/SOX4 2 GO:0090026 positive regulation of monocyte chemotaxis 2/313 21/18722 0.0474769972080947 0.194558588128328 SERPINE1/LGMN 2 GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2/313 21/18722 0.0474769972080947 0.194558588128328 HSPA1A/NMT1 2 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 2/313 21/18722 0.0474769972080947 0.194558588128328 MIF/PTTG1IP 2 GO:1902579 multi-organism localization 2/313 21/18722 0.0474769972080947 0.194558588128328 CAV1/CAV2 2 GO:1902644 tertiary alcohol metabolic process 2/313 21/18722 0.0474769972080947 0.194558588128328 CYP11A1/AKR1B1 2 GO:1903427 negative regulation of reactive oxygen species biosynthetic process 2/313 21/18722 0.0474769972080947 0.194558588128328 PAGE4/RHOA 2 GO:0010952 positive regulation of peptidase activity 7/313 197/18722 0.048109215065265 0.196333250002131 CAV1/FN1/PMAIP1/PDCD6/FBLN1/RHOA/LGMN 7 GO:0006413 translational initiation 5/313 118/18722 0.0481727607775509 0.196333250002131 RPS17/EIF4H/EIF4B/HSPB1/PPP1R15A 5 GO:0009409 response to cold 3/313 49/18722 0.0485151242468969 0.196333250002131 PLAC8/FOS/ATP2B1 3 GO:0010823 negative regulation of mitochondrion organization 3/313 49/18722 0.0485151242468969 0.196333250002131 GPX1/HSPA1A/CLU 3 GO:0021515 cell differentiation in spinal cord 3/313 49/18722 0.0485151242468969 0.196333250002131 LMO4/ISL1/SOX4 3 GO:0034332 adherens junction organization 3/313 49/18722 0.0485151242468969 0.196333250002131 DSP/ACTB/JAM3 3 GO:0060964 regulation of gene silencing by miRNA 3/313 49/18722 0.0485151242468969 0.196333250002131 DDX5/NEAT1/KCNQ1OT1 3 GO:0072091 regulation of stem cell proliferation 3/313 49/18722 0.0485151242468969 0.196333250002131 FBLN1/GJA1/FERMT1 3 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 3/313 49/18722 0.0485151242468969 0.196333250002131 JUN/GJA1/ADAMTS1 3 GO:1904752 regulation of vascular associated smooth muscle cell migration 3/313 49/18722 0.0485151242468969 0.196333250002131 RHOA/TPM1/ADAMTS1 3 GO:0046364 monosaccharide biosynthetic process 4/313 82/18722 0.0486122025800266 0.196333250002131 TPI1/PGK1/AKR1B1/PGP 4 GO:2001057 reactive nitrogen species metabolic process 4/313 82/18722 0.0486122025800266 0.196333250002131 CAV1/DYNLL1/INSR/CLU 4 GO:1902107 positive regulation of leukocyte differentiation 6/313 157/18722 0.0486320606125583 0.196333250002131 ANXA1/FOS/JUN/SOX4/RHOA/ID2 6 GO:1903708 positive regulation of hemopoiesis 6/313 157/18722 0.0486320606125583 0.196333250002131 ANXA1/FOS/JUN/SOX4/RHOA/ID2 6 GO:0010906 regulation of glucose metabolic process 5/313 119/18722 0.0496291020716726 0.199934382631596 IGF2/PMAIP1/PHLDA2/INSR/PGP 5 GO:0031398 positive regulation of protein ubiquitination 5/313 119/18722 0.0496291020716726 0.199934382631596 CAV1/PDCD6/PTTG1IP/CDC20/ARRDC3 5 GO:0031397 negative regulation of protein ubiquitination 4/313 83/18722 0.0504297057798514 0.202730612358917 CAV1/RPL23/SOX4/HSPA1A 4 GO:0048678 response to axon injury 4/313 83/18722 0.0504297057798514 0.202730612358917 ISL1/NREP/STK24/JAM3 4 GO:0071709 membrane assembly 3/313 50/18722 0.0509959226958061 0.203597864317068 CAV1/CAV2/S100A10 3 GO:1904738 vascular associated smooth muscle cell migration 3/313 50/18722 0.0509959226958061 0.203597864317068 RHOA/TPM1/ADAMTS1 3 GO:2000677 regulation of transcription regulatory region DNA binding 3/313 50/18722 0.0509959226958061 0.203597864317068 SRI/TMSB4X/PARP1 3 GO:0002761 regulation of myeloid leukocyte differentiation 5/313 120/18722 0.0511111481713615 0.203597864317068 FBN1/FOS/JUN/CEBPB/ID2 5 GO:0030218 erythrocyte differentiation 5/313 120/18722 0.0511111481713615 0.203597864317068 PRMT1/UBA5/HSPA1A/TGFBR3/ID2 5 GO:1903169 regulation of calcium ion transmembrane transport 6/313 159/18722 0.0511387450847091 0.203597864317068 C4orf3/GSTO1/SRI/PDE4B/CALM1/AHNAK 6 GO:0001819 positive regulation of cytokine production 13/313 467/18722 0.0511715294846986 0.203597864317068 GAPDH/ANXA1/SLC7A5/MIF/SERPINE1/ISL1/CEBPB/PDE4B/HSPA1A/HSPB1/EGR1/CLU/FERMT1 13 GO:0072522 purine-containing compound biosynthetic process 7/313 200/18722 0.051407545466296 0.203597864317068 ALDOA/ENO1/SLC26A2/TMSB4X/PARP1/MPC2/TECR 7 GO:0002320 lymphoid progenitor cell differentiation 2/313 22/18722 0.0516615542238738 0.203597864317068 SOX4/HES1 2 GO:0006907 pinocytosis 2/313 22/18722 0.0516615542238738 0.203597864317068 CAV1/CLN3 2 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 2/313 22/18722 0.0516615542238738 0.203597864317068 GSTO1/CALM1 2 GO:0032069 regulation of nuclease activity 2/313 22/18722 0.0516615542238738 0.203597864317068 HSPA1A/TMBIM6 2 GO:0032891 negative regulation of organic acid transport 2/313 22/18722 0.0516615542238738 0.203597864317068 SLC43A2/RGS2 2 GO:0035024 negative regulation of Rho protein signal transduction 2/313 22/18722 0.0516615542238738 0.203597864317068 ITGB1/STMN1 2 GO:0048026 positive regulation of mRNA splicing, via spliceosome 2/313 22/18722 0.0516615542238738 0.203597864317068 PRDX6/TRA2B 2 GO:0050860 negative regulation of T cell receptor signaling pathway 2/313 22/18722 0.0516615542238738 0.203597864317068 PHPT1/EZR 2 GO:0051220 cytoplasmic sequestering of protein 2/313 22/18722 0.0516615542238738 0.203597864317068 SRI/TMSB4X 2 GO:0060965 negative regulation of gene silencing by miRNA 2/313 22/18722 0.0516615542238738 0.203597864317068 NEAT1/KCNQ1OT1 2 GO:2000773 negative regulation of cellular senescence 2/313 22/18722 0.0516615542238738 0.203597864317068 YBX1/PLK2 2 GO:0006835 dicarboxylic acid transport 4/313 84/18722 0.0522841046164181 0.205625605655686 SLC26A2/ITGB1/SLC13A3/GJA1 4 GO:0042310 vasoconstriction 4/313 84/18722 0.0522841046164181 0.205625605655686 CAV1/ATP2B1/RHOA/GJA1 4 GO:0060402 calcium ion transport into cytosol 6/313 160/18722 0.0524212300598544 0.205952139151564 CAV1/GSTO1/SRI/TMBIM6/CALM1/MCOLN3 6 GO:0051051 negative regulation of transport 13/313 470/18722 0.0533114839080035 0.209233834265742 CAV1/C4orf3/ANXA1/GSTO1/TNFRSF1A/SRI/OAZ1/TMBIM6/SLC43A2/CALM1/GJA1/FERMT1/RGS2 13 GO:0014009 glial cell proliferation 3/313 51/18722 0.0535371844066828 0.209256736176839 SOX4/CLU/HES1 3 GO:0021872 forebrain generation of neurons 3/313 51/18722 0.0535371844066828 0.209256736176839 NRP2/RHOA/HES1 3 GO:0045104 intermediate filament cytoskeleton organization 3/313 51/18722 0.0535371844066828 0.209256736176839 KRT18/DSP/DST 3 GO:0060043 regulation of cardiac muscle cell proliferation 3/313 51/18722 0.0535371844066828 0.209256736176839 GJA1/TGFBR3/CCNB1 3 GO:0009913 epidermal cell differentiation 7/313 202/18722 0.0536838226716316 0.209478626701689 FLNB/ANXA1/DSP/CLIC4/ERRFI1/MCOLN3/HES1 7 GO:1903311 regulation of mRNA metabolic process 9/313 288/18722 0.0537040030630019 0.209478626701689 DDX5/YBX3/FUS/PKP3/YBX1/BTG2/PRDX6/TRA2B/CCNB1 9 GO:0051928 positive regulation of calcium ion transport 5/313 122/18722 0.05415240863374 0.210025840148061 CAV1/GSTO1/ATP2B1/SRI/CALM1 5 GO:1990266 neutrophil migration 5/313 122/18722 0.05415240863374 0.210025840148061 CD99/BSG/CSF3R/PDE4B/JAM3 5 GO:0001656 metanephros development 4/313 85/18722 0.0541753020817957 0.210025840148061 FBN1/AKR1B1/EGR1/HES1 4 GO:0009142 nucleoside triphosphate biosynthetic process 4/313 85/18722 0.0541753020817957 0.210025840148061 ALDOA/ENO1/TMSB4X/PARP1 4 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 4/313 85/18722 0.0541753020817957 0.210025840148061 CAV1/TNFRSF1A/ISL1/HES1 4 GO:0055013 cardiac muscle cell development 4/313 85/18722 0.0541753020817957 0.210025840148061 ISL1/FHL2/CCNB1/RGS2 4 GO:0050808 synapse organization 12/313 426/18722 0.055350205349216 0.213293058842244 ACTG1/NRP2/RAB17/PFN1/CFL1/INSR/RHOA/ACTB/CLN3/CDC20/PPFIBP1/LGMN 12 GO:1903131 mononuclear cell differentiation 12/313 426/18722 0.055350205349216 0.213293058842244 DHRS2/ANXA1/JUN/SOX4/MYH9/RHOA/TPD52/CEBPB/ITGB1/ITGB8/EGR1/ID2 12 GO:0010811 positive regulation of cell-substrate adhesion 5/313 123/18722 0.0557116316120094 0.213293058842244 PLEKHA2/FN1/CCDC80/S100A10/FERMT1 5 GO:0003283 atrial septum development 2/313 23/18722 0.055972468451502 0.213293058842244 ISL1/SOX4 2 GO:0019430 removal of superoxide radicals 2/313 23/18722 0.055972468451502 0.213293058842244 PRDX1/SOD3 2 GO:0045932 negative regulation of muscle contraction 2/313 23/18722 0.055972468451502 0.213293058842244 SRI/RGS2 2 GO:0051131 chaperone-mediated protein complex assembly 2/313 23/18722 0.055972468451502 0.213293058842244 HSPA1A/CLU 2 GO:0060547 negative regulation of necrotic cell death 2/313 23/18722 0.055972468451502 0.213293058842244 CAV1/YBX3 2 GO:0071514 genetic imprinting 2/313 23/18722 0.055972468451502 0.213293058842244 IGF2/DNMT3A 2 GO:1904666 regulation of ubiquitin protein ligase activity 2/313 23/18722 0.055972468451502 0.213293058842244 RPL23/CDC20 2 GO:2000737 negative regulation of stem cell differentiation 2/313 23/18722 0.055972468451502 0.213293058842244 LBH/HES1 2 GO:1901888 regulation of cell junction assembly 7/313 204/18722 0.0560223601229189 0.213293058842244 CAV1/ACTG1/RAB17/RHOA/S100A10/PTPRA/GJA1 7 GO:0022406 membrane docking 4/313 86/18722 0.0561031866252375 0.213293058842244 CAV2/EZR/CALM1/CLN3 4 GO:2001251 negative regulation of chromosome organization 4/313 86/18722 0.0561031866252375 0.213293058842244 PTTG1/PARP1/TOP2A/CCNB1 4 GO:0021545 cranial nerve development 3/313 52/18722 0.0561382556083868 0.213293058842244 NRP2/ISL1/HES1 3 GO:0043392 negative regulation of DNA binding 3/313 52/18722 0.0561382556083868 0.213293058842244 JUN/SRI/TMSB4X 3 GO:0045103 intermediate filament-based process 3/313 52/18722 0.0561382556083868 0.213293058842244 KRT18/DSP/DST 3 GO:0051496 positive regulation of stress fiber assembly 3/313 52/18722 0.0561382556083868 0.213293058842244 RHOA/S100A10/TPM1 3 GO:0060147 regulation of posttranscriptional gene silencing 3/313 52/18722 0.0561382556083868 0.213293058842244 DDX5/NEAT1/KCNQ1OT1 3 GO:0048568 embryonic organ development 12/313 427/18722 0.0561385986235695 0.213293058842244 KRT19/KRT8/IGF2/FBN1/MBD3/RPL38/PHLDA2/CEBPB/MFAP5/TRA2B/ID2/HES1 12 GO:0021537 telencephalon development 8/313 248/18722 0.0574802983017976 0.218172976704829 C12orf57/RHOA/TACC2/BTG2/TRA2B/SLC2A1/ID2/HES1 8 GO:0001776 leukocyte homeostasis 4/313 87/18722 0.058067632459042 0.219963658479177 ANXA1/PMAIP1/PDE4B/JAM3 4 GO:0048041 focal adhesion assembly 4/313 87/18722 0.058067632459042 0.219963658479177 ACTG1/RHOA/S100A10/PTPRA 4 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 8/313 249/18722 0.0585706257036525 0.221163536197232 GAPDH/NEK6/WLS/TNFRSF1A/RHOA/HSPB1/GJA1/PLK2 8 GO:0001822 kidney development 9/313 293/18722 0.0585819245609902 0.221163536197232 FBN1/ADAMTS6/SOX4/MAGED1/RHOA/AKR1B1/EGR1/ADAMTS1/HES1 9 GO:0051438 regulation of ubiquitin-protein transferase activity 3/313 53/18722 0.0587984534634387 0.221163536197232 RPL23/CDC20/ARRDC3 3 GO:0060966 regulation of gene silencing by RNA 3/313 53/18722 0.0587984534634387 0.221163536197232 DDX5/NEAT1/KCNQ1OT1 3 GO:1903202 negative regulation of oxidative stress-induced cell death 3/313 53/18722 0.0587984534634387 0.221163536197232 PAGE4/GPX1/HSPB1 3 GO:2000772 regulation of cellular senescence 3/313 53/18722 0.0587984534634387 0.221163536197232 NEK6/YBX1/PLK2 3 GO:0055007 cardiac muscle cell differentiation 5/313 125/18722 0.0589072302873637 0.221163536197232 ISL1/ITGB1/FHL2/CCNB1/RGS2 5 GO:0071621 granulocyte chemotaxis 5/313 125/18722 0.0589072302873637 0.221163536197232 ANXA1/BSG/CSF3R/PDE4B/JAM3 5 GO:1904375 regulation of protein localization to cell periphery 5/313 125/18722 0.0589072302873637 0.221163536197232 EZR/TMBIM1/ITGB1/ACTB/CLN3 5 GO:0006790 sulfur compound metabolic process 10/313 339/18722 0.0595901319946017 0.223282033298152 CLIC3/GSTO1/GPX1/IDH1/GPX4/SLC26A2/CLIC1/MPC2/TECR/B3GNT2 10 GO:0051604 protein maturation 9/313 294/18722 0.0595906567628845 0.223282033298152 ENO1/SERPINE1/SOX4/PGK1/DHCR24/MYH9/PARP1/CLN3/LGMN 9 GO:0050679 positive regulation of epithelial cell proliferation 7/313 207/18722 0.0596474462474969 0.223282033298152 HTRA1/IGF2/NRP2/PDCD6/CAV2/VEGFB/PGF 7 GO:0007260 tyrosine phosphorylation of STAT protein 4/313 88/18722 0.0600684998670659 0.223478579023771 CAV1/TNFRSF1A/ISL1/HES1 4 GO:0003148 outflow tract septum morphogenesis 2/313 24/18722 0.0604043755753769 0.223478579023771 NRP2/ISL1 2 GO:0007035 vacuolar acidification 2/313 24/18722 0.0604043755753769 0.223478579023771 CLIC4/CLN3 2 GO:0030810 positive regulation of nucleotide biosynthetic process 2/313 24/18722 0.0604043755753769 0.223478579023771 ENO1/TMSB4X 2 GO:0048641 regulation of skeletal muscle tissue development 2/313 24/18722 0.0604043755753769 0.223478579023771 IGF2/YBX3 2 GO:0051043 regulation of membrane protein ectodomain proteolysis 2/313 24/18722 0.0604043755753769 0.223478579023771 TIMP2/TIMP3 2 GO:0060149 negative regulation of posttranscriptional gene silencing 2/313 24/18722 0.0604043755753769 0.223478579023771 NEAT1/KCNQ1OT1 2 GO:0060967 negative regulation of gene silencing by RNA 2/313 24/18722 0.0604043755753769 0.223478579023771 NEAT1/KCNQ1OT1 2 GO:0070841 inclusion body assembly 2/313 24/18722 0.0604043755753769 0.223478579023771 HSPA1A/CLU 2 GO:0120255 olefinic compound biosynthetic process 2/313 24/18722 0.0604043755753769 0.223478579023771 HSD17B1/EGR1 2 GO:1900373 positive regulation of purine nucleotide biosynthetic process 2/313 24/18722 0.0604043755753769 0.223478579023771 ENO1/TMSB4X 2 GO:2000209 regulation of anoikis 2/313 24/18722 0.0604043755753769 0.223478579023771 CAV1/ITGB1 2 GO:0043112 receptor metabolic process 6/313 166/18722 0.0605260140958915 0.223494214998117 CAV1/CD63/EZR/INSR/ITGB1/LGMN 6 GO:1902904 negative regulation of supramolecular fiber organization 6/313 166/18722 0.0605260140958915 0.223494214998117 PFN1/TMSB4X/SCIN/STMN1/CLU/KANK4 6 GO:0050727 regulation of inflammatory response 11/313 386/18722 0.0606555740654621 0.223755591537998 ANXA1/NEAT1/GPX1/TNFRSF1A/GPX4/SERPINE1/ISL1/CTSC/CEBPB/TMSB4X/PLK2 11 GO:0086002 cardiac muscle cell action potential involved in contraction 3/313 54/18722 0.0615170677735275 0.22671391772877 CAV1/DSP/GJA1 3 GO:0002683 negative regulation of immune system process 12/313 434/18722 0.0618694448748428 0.227792047039194 HTRA1/SERPINB9/FBN1/ANXA1/GPX1/MIF/PHPT1/EZR/CEBPB/TMBIM6/PLK2/ID2 12 GO:0034767 positive regulation of ion transmembrane transport 6/313 167/18722 0.0619453063829323 0.227850996521568 GSTO1/TCAF1/SRI/ITGB1/TMSB4X/CALM1 6 GO:1900407 regulation of cellular response to oxidative stress 4/313 89/18722 0.062105635515488 0.22822022626203 PAGE4/GPX1/HSPB1/PARP1 4 GO:0035270 endocrine system development 5/313 127/18722 0.0622055722318702 0.228367033256249 ANXA1/LY6E/ISL1/SOX4/HES1 5 GO:0099173 postsynapse organization 6/313 168/18722 0.0633841964442465 0.232469784068638 ACTG1/NRP2/CFL1/INSR/ACTB/LGMN 6 GO:0010676 positive regulation of cellular carbohydrate metabolic process 3/313 55/18722 0.0642933626273797 0.233496195241915 IGF2/PMAIP1/INSR 3 GO:0044091 membrane biogenesis 3/313 55/18722 0.0642933626273797 0.233496195241915 CAV1/CAV2/S100A10 3 GO:0098900 regulation of action potential 3/313 55/18722 0.0642933626273797 0.233496195241915 CAV1/DSP/CALM1 3 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 2/313 25/18722 0.0649520543107928 0.233496195241915 RHOA/GJA1 2 GO:0010954 positive regulation of protein processing 2/313 25/18722 0.0649520543107928 0.233496195241915 ENO1/MYH9 2 GO:0032469 endoplasmic reticulum calcium ion homeostasis 2/313 25/18722 0.0649520543107928 0.233496195241915 HERPUD1/TMBIM6 2 GO:0032753 positive regulation of interleukin-4 production 2/313 25/18722 0.0649520543107928 0.233496195241915 SLC7A5/CEBPB 2 GO:0033233 regulation of protein sumoylation 2/313 25/18722 0.0649520543107928 0.233496195241915 HMG20B/EGR1 2 GO:0050927 positive regulation of positive chemotaxis 2/313 25/18722 0.0649520543107928 0.233496195241915 VEGFB/PGF 2 GO:0051450 myoblast proliferation 2/313 25/18722 0.0649520543107928 0.233496195241915 MALAT1/GPX1 2 GO:0060074 synapse maturation 2/313 25/18722 0.0649520543107928 0.233496195241915 PFN1/CDC20 2 GO:0060706 cell differentiation involved in embryonic placenta development 2/313 25/18722 0.0649520543107928 0.233496195241915 KRT19/KRT8 2 GO:0061436 establishment of skin barrier 2/313 25/18722 0.0649520543107928 0.233496195241915 LSR/STMN1 2 GO:0062009 secondary palate development 2/313 25/18722 0.0649520543107928 0.233496195241915 ITGB8/TGFBR3 2 GO:0071450 cellular response to oxygen radical 2/313 25/18722 0.0649520543107928 0.233496195241915 PRDX1/SOD3 2 GO:0071451 cellular response to superoxide 2/313 25/18722 0.0649520543107928 0.233496195241915 PRDX1/SOD3 2 GO:0072012 glomerulus vasculature development 2/313 25/18722 0.0649520543107928 0.233496195241915 EGR1/HES1 2 GO:0090169 regulation of spindle assembly 2/313 25/18722 0.0649520543107928 0.233496195241915 CCSAP/HSPA1A 2 GO:1903792 negative regulation of anion transport 2/313 25/18722 0.0649520543107928 0.233496195241915 SLC43A2/RGS2 2 GO:1904753 negative regulation of vascular associated smooth muscle cell migration 2/313 25/18722 0.0649520543107928 0.233496195241915 RHOA/TPM1 2 GO:1905048 regulation of metallopeptidase activity 2/313 25/18722 0.0649520543107928 0.233496195241915 TIMP2/TIMP3 2 GO:0007498 mesoderm development 5/313 129/18722 0.0656064067269853 0.235626028688333 WLS/RPL38/MEST/ITGB1/GJA1 5 GO:0002065 columnar/cuboidal epithelial cell differentiation 4/313 91/18722 0.0662880319870988 0.237519450718688 SERPINE1/SOX4/CEBPB/HES1 4 GO:0060191 regulation of lipase activity 4/313 91/18722 0.0662880319870988 0.237519450718688 ANXA1/RHOA/FLT1/RGS2 4 GO:0030178 negative regulation of Wnt signaling pathway 6/313 170/18722 0.066320771240863 0.237519450718688 CAV1/TLE4/ISL1/CTNND1/EGR1/FERMT1 6 GO:0010332 response to gamma radiation 3/313 56/18722 0.0671265779925725 0.239728782755838 GPX1/PARP1/EGR1 3 GO:0048255 mRNA stabilization 3/313 56/18722 0.0671265779925725 0.239728782755838 YBX3/FUS/YBX1 3 GO:1904645 response to amyloid-beta 3/313 56/18722 0.0671265779925725 0.239728782755838 PARP1/GJA1/LGMN 3 GO:0001708 cell fate specification 4/313 92/18722 0.0684329208749975 0.24393645109655 LMO4/ISL1/FKBP8/ITGB1 4 GO:1903312 negative regulation of mRNA metabolic process 4/313 92/18722 0.0684329208749975 0.24393645109655 YBX3/FUS/PKP3/YBX1 4 GO:0000082 G1/S transition of mitotic cell cycle 7/313 214/18722 0.0686563789125097 0.244504054742679 ANXA1/BACH1/SOX4/ITGB1/ADAMTS1/PLK2/ID2 7 GO:0060070 canonical Wnt signaling pathway 9/313 303/18722 0.0691717877911504 0.246109342169074 CAV1/WLS/TLE4/ISL1/SOX4/LGR5/CTNND1/EGR1/FERMT1 9 GO:0002092 positive regulation of receptor internalization 2/313 26/18722 0.0696104231461092 0.246288922785537 CD63/INSR 2 GO:0014829 vascular associated smooth muscle contraction 2/313 26/18722 0.0696104231461092 0.246288922785537 ATP2B1/RHOA 2 GO:0050926 regulation of positive chemotaxis 2/313 26/18722 0.0696104231461092 0.246288922785537 VEGFB/PGF 2 GO:0060037 pharyngeal system development 2/313 26/18722 0.0696104231461092 0.246288922785537 ISL1/HES1 2 GO:0060544 regulation of necroptotic process 2/313 26/18722 0.0696104231461092 0.246288922785537 CAV1/YBX3 2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway 2/313 26/18722 0.0696104231461092 0.246288922785537 PDE4B/ARRDC3 2 GO:0002011 morphogenesis of an epithelial sheet 3/313 57/18722 0.0700159312528428 0.246577844846968 CD151/RHOA/FERMT1 3 GO:0006949 syncytium formation 3/313 57/18722 0.0700159312528428 0.246577844846968 ADAM12/MYH9/ERVH48-1 3 GO:0030219 megakaryocyte differentiation 3/313 57/18722 0.0700159312528428 0.246577844846968 PRMT1/UBA5/SCIN 3 GO:0033619 membrane protein proteolysis 3/313 57/18722 0.0700159312528428 0.246577844846968 TIMP2/TIMP3/MYH9 3 GO:0050891 multicellular organismal water homeostasis 3/313 57/18722 0.0700159312528428 0.246577844846968 AKR1B1/LSR/STMN1 3 GO:0045927 positive regulation of growth 8/313 259/18722 0.0701933574010139 0.246974225162347 IGF2/FN1/YBX3/EZR/INSR/RHOA/TGFBR3/CCNB1 8 GO:0090398 cellular senescence 4/313 93/18722 0.0706133347640357 0.248222498104048 NEK6/YBX1/PLK2/ID2 4 GO:0000910 cytokinesis 6/313 173/18722 0.0708725204728786 0.248903768856318 MYH9/RHOA/CALM1/STMN1/RHOB/PLK2 6 GO:0050870 positive regulation of T cell activation 7/313 216/18722 0.0713723656286594 0.250428199030697 IGF2/CAV1/EFNB1/ANXA1/SOX4/RHOA/HES1 7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 4/313 94/18722 0.0728290569460505 0.254127241868206 ACTB/SERTAD1/CCNL1/CCNB1 4 GO:0002042 cell migration involved in sprouting angiogenesis 4/313 94/18722 0.0728290569460505 0.254127241868206 ANXA1/RHOA/ITGB1/PLK2 4 GO:0002690 positive regulation of leukocyte chemotaxis 4/313 94/18722 0.0728290569460505 0.254127241868206 SERPINE1/VEGFB/PGF/LGMN 4 GO:0001954 positive regulation of cell-matrix adhesion 3/313 58/18722 0.0729606186923955 0.254127241868206 PLEKHA2/S100A10/FERMT1 3 GO:0002763 positive regulation of myeloid leukocyte differentiation 3/313 58/18722 0.0729606186923955 0.254127241868206 FOS/JUN/ID2 3 GO:0002931 response to ischemia 3/313 58/18722 0.0729606186923955 0.254127241868206 CAV1/GJA1/EGR1 3 GO:0035904 aorta development 3/313 58/18722 0.0729606186923955 0.254127241868206 ADAMTS6/SOX4/HES1 3 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 3/313 58/18722 0.0729606186923955 0.254127241868206 CAV1/PMAIP1/EIF5A 3 GO:0051480 regulation of cytosolic calcium ion concentration 10/313 353/18722 0.0736861621073753 0.25641976155647 CAV1/GSTO1/ATP2B1/SRI/CAV2/TMBIM6/CALM1/CLN3/GJA1/MCOLN3 10 GO:0052126 movement in host environment 6/313 175/18722 0.0740047749309984 0.256857994830333 CAV1/LY6E/BSG/CAV2/ITGB1/HSPA1A 6 GO:0009651 response to salt stress 2/313 27/18722 0.0743745371533186 0.256857994830333 EFHD1/AKR1B1 2 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 2/313 27/18722 0.0743745371533186 0.256857994830333 GSTO1/CALM1 2 GO:0032781 positive regulation of ATPase activity 2/313 27/18722 0.0743745371533186 0.256857994830333 PFN1/TPM1 2 GO:0033561 regulation of water loss via skin 2/313 27/18722 0.0743745371533186 0.256857994830333 LSR/STMN1 2 GO:0051953 negative regulation of amine transport 2/313 27/18722 0.0743745371533186 0.256857994830333 SLC43A2/RGS2 2 GO:0061437 renal system vasculature development 2/313 27/18722 0.0743745371533186 0.256857994830333 EGR1/HES1 2 GO:0061440 kidney vasculature development 2/313 27/18722 0.0743745371533186 0.256857994830333 EGR1/HES1 2 GO:0006874 cellular calcium ion homeostasis 12/313 448/18722 0.074464381720112 0.256857994830333 CAV1/STC2/GSTO1/ATP2B1/SRI/CAV2/HERPUD1/TMBIM6/CALM1/CLN3/GJA1/MCOLN3 12 GO:0008277 regulation of G protein-coupled receptor signaling pathway 5/313 134/18722 0.0745542643255891 0.256857994830333 PDE4B/NMT1/ARRDC3/STMN1/RGS2 5 GO:0042552 myelination 5/313 134/18722 0.0745542643255891 0.256857994830333 SERINC5/CTSC/JAM3/EPB41L3/CLU 5 GO:0008585 female gonad development 4/313 95/18722 0.0750798589865325 0.257735818901469 CYP19A1/IDH1/CEBPB/ADAMTS1 4 GO:0042773 ATP synthesis coupled electron transport 4/313 95/18722 0.0750798589865325 0.257735818901469 UQCRB/COX4I1/NDUFB1/CCNB1 4 GO:0042775 mitochondrial ATP synthesis coupled electron transport 4/313 95/18722 0.0750798589865325 0.257735818901469 UQCRB/COX4I1/NDUFB1/CCNB1 4 GO:0042982 amyloid precursor protein metabolic process 4/313 95/18722 0.0750798589865325 0.257735818901469 ITM2B/DHCR24/CLN3/CLU 4 GO:0034764 positive regulation of transmembrane transport 7/313 219/18722 0.075564794709928 0.259166822937564 GSTO1/TCAF1/SRI/INSR/ITGB1/TMSB4X/CALM1 7 GO:0019369 arachidonic acid metabolic process 3/313 59/18722 0.0759598169286886 0.260287149457712 CYP2J2/GPX1/GPX4 3 GO:0002064 epithelial cell development 7/313 220/18722 0.0769938394731505 0.26344406302681 FLNB/GPX1/TNFRSF1A/CLIC4/EZR/ADAMTSL4/AKR1B1 7 GO:0043405 regulation of MAP kinase activity 6/313 177/18722 0.0772150155584457 0.26344406302681 CAV1/INSR/MAGED1/FLT1/MAP3K4/RGS2 6 GO:0030510 regulation of BMP signaling pathway 4/313 96/18722 0.0773655010412328 0.26344406302681 HTRA1/FBN1/FKBP8/HES1 4 GO:0034620 cellular response to unfolded protein 4/313 96/18722 0.0773655010412328 0.26344406302681 HERPUD1/HSPA1A/TMBIM6/PPP1R15A 4 GO:0051304 chromosome separation 4/313 96/18722 0.0773655010412328 0.26344406302681 NEK6/PTTG1/TOP2A/CCNB1 4 GO:0055017 cardiac muscle tissue growth 4/313 96/18722 0.0773655010412328 0.26344406302681 GJA1/TGFBR3/CCNB1/RGS2 4 GO:1901655 cellular response to ketone 4/313 96/18722 0.0773655010412328 0.26344406302681 ATP2B1/AKR1B1/ERRFI1/NR3C1 4 GO:0030522 intracellular receptor signaling pathway 8/313 265/18722 0.0777990553912522 0.264683649575065 LBH/DDX5/ISL1/UBA5/RHOA/HSPA1A/PARP1/NR3C1 8 GO:0007272 ensheathment of neurons 5/313 136/18722 0.0783102790516773 0.265947575691111 SERINC5/CTSC/JAM3/EPB41L3/CLU 5 GO:0008366 axon ensheathment 5/313 136/18722 0.0783102790516773 0.265947575691111 SERINC5/CTSC/JAM3/EPB41L3/CLU 5 GO:0006109 regulation of carbohydrate metabolic process 6/313 178/18722 0.078849303067265 0.266195831072166 IGF2/PMAIP1/PHLDA2/PGAM1/INSR/PGP 6 GO:0009266 response to temperature stimulus 6/313 178/18722 0.078849303067265 0.266195831072166 PLAC8/FOS/ATP2B1/PDCD6/HSPA1A/DNAJB4 6 GO:0006081 cellular aldehyde metabolic process 3/313 60/18722 0.0790126842951268 0.266195831072166 TPI1/RDH13/IDH1 3 GO:0006893 Golgi to plasma membrane transport 3/313 60/18722 0.0790126842951268 0.266195831072166 KRT18/CLN3/EXOC1 3 GO:0033866 nucleoside bisphosphate biosynthetic process 3/313 60/18722 0.0790126842951268 0.266195831072166 SLC26A2/MPC2/TECR 3 GO:0034030 ribonucleoside bisphosphate biosynthetic process 3/313 60/18722 0.0790126842951268 0.266195831072166 SLC26A2/MPC2/TECR 3 GO:0034033 purine nucleoside bisphosphate biosynthetic process 3/313 60/18722 0.0790126842951268 0.266195831072166 SLC26A2/MPC2/TECR 3 GO:0051851 modulation by host of symbiont process 3/313 60/18722 0.0790126842951268 0.266195831072166 JUN/CAV2/CFL1 3 GO:0060038 cardiac muscle cell proliferation 3/313 60/18722 0.0790126842951268 0.266195831072166 GJA1/TGFBR3/CCNB1 3 GO:0000303 response to superoxide 2/313 28/18722 0.0792395848656448 0.266488603872359 PRDX1/SOD3 2 GO:0060325 face morphogenesis 2/313 28/18722 0.0792395848656448 0.266488603872359 CRISPLD1/ANKRD11 2 GO:0120162 positive regulation of cold-induced thermogenesis 4/313 97/18722 0.0796857321723784 0.267516386578699 PLAC8/CAV1/CEBPB/GJA1 4 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 4/313 97/18722 0.0796857321723784 0.267516386578699 GPX1/SERPINE1/TMBIM1/HSPA1A 4 GO:0030879 mammary gland development 5/313 137/18722 0.0802258494198231 0.268619005049487 CAV1/LBH/GPX1/CEBPB/ID2 5 GO:0050671 positive regulation of lymphocyte proliferation 5/313 137/18722 0.0802258494198231 0.268619005049487 IGF2/EFNB1/ANXA1/MIF/HES1 5 GO:0055123 digestive system development 5/313 137/18722 0.0802258494198231 0.268619005049487 IGF2/WLS/ID2/CCNB1/HES1 5 GO:0045787 positive regulation of cell cycle 9/313 313/18722 0.0808885616165376 0.270599959643373 IGF2/ANXA1/INSR/RHOA/PPP1R10/ADAMTS1/LGMN/CCNB1/HES1 9 GO:0051348 negative regulation of transferase activity 8/313 268/18722 0.0817802443687307 0.272275129093794 CAV1/RPL23/MLLT1/GADD45B/PHPT1/HSPB1/ERRFI1/RGS2 8 GO:0003333 amino acid transmembrane transport 4/313 98/18722 0.0820402906642317 0.272275129093794 SLC7A5/ITGB1/SLC43A2/RGS2 4 GO:0043502 regulation of muscle adaptation 4/313 98/18722 0.0820402906642317 0.272275129093794 TNFRSF1A/PARP1/ERRFI1/RGS2 4 GO:1902882 regulation of response to oxidative stress 4/313 98/18722 0.0820402906642317 0.272275129093794 PAGE4/GPX1/HSPB1/PARP1 4 GO:1904029 regulation of cyclin-dependent protein kinase activity 4/313 98/18722 0.0820402906642317 0.272275129093794 ACTB/SERTAD1/CCNL1/CCNB1 4 GO:0034113 heterotypic cell-cell adhesion 3/313 61/18722 0.082118362175064 0.272275129093794 DSP/ITGB1/JAM3 3 GO:0042255 ribosome assembly 3/313 61/18722 0.082118362175064 0.272275129093794 RPS27/RPL38/RPS28 3 GO:0032273 positive regulation of protein polymerization 5/313 138/18722 0.0821663303670451 0.272275129093794 PFN1/RHOA/SCIN/HSPA1A/IQGAP2 5 GO:0032946 positive regulation of mononuclear cell proliferation 5/313 138/18722 0.0821663303670451 0.272275129093794 IGF2/EFNB1/ANXA1/MIF/HES1 5 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 5/313 138/18722 0.0821663303670451 0.272275129093794 CAV1/PDCD6/PTTG1IP/CDC20/ARRDC3 5 GO:0043409 negative regulation of MAPK cascade 6/313 180/18722 0.0821760239896952 0.272275129093794 CAV1/TIMP3/FBLN1/EZR/ERRFI1/RGS2 6 GO:0030216 keratinocyte differentiation 5/313 139/18722 0.0841316157478322 0.275152592305348 FLNB/ANXA1/DSP/CLIC4/ERRFI1 5 GO:0051783 regulation of nuclear division 5/313 139/18722 0.0841316157478322 0.275152592305348 IGF2/CAV2/INSR/CDC20/CCNB1 5 GO:0000305 response to oxygen radical 2/313 29/18722 0.084200885220838 0.275152592305348 PRDX1/SOD3 2 GO:0001773 myeloid dendritic cell activation 2/313 29/18722 0.084200885220838 0.275152592305348 DHRS2/ITGB8 2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus 2/313 29/18722 0.084200885220838 0.275152592305348 GPX1/PLK2 2 GO:0003209 cardiac atrium morphogenesis 2/313 29/18722 0.084200885220838 0.275152592305348 ISL1/SOX4 2 GO:0005979 regulation of glycogen biosynthetic process 2/313 29/18722 0.084200885220838 0.275152592305348 IGF2/INSR 2 GO:0010962 regulation of glucan biosynthetic process 2/313 29/18722 0.084200885220838 0.275152592305348 IGF2/INSR 2 GO:0015701 bicarbonate transport 2/313 29/18722 0.084200885220838 0.275152592305348 SLC26A2/CYB5R1 2 GO:0021591 ventricular system development 2/313 29/18722 0.084200885220838 0.275152592305348 SEMA6D/C12orf57 2 GO:0040018 positive regulation of multicellular organism growth 2/313 29/18722 0.084200885220838 0.275152592305348 IGF2/EZR 2 GO:0060969 negative regulation of gene silencing 2/313 29/18722 0.084200885220838 0.275152592305348 NEAT1/KCNQ1OT1 2 GO:0062098 regulation of programmed necrotic cell death 2/313 29/18722 0.084200885220838 0.275152592305348 CAV1/YBX3 2 GO:0071549 cellular response to dexamethasone stimulus 2/313 29/18722 0.084200885220838 0.275152592305348 ERRFI1/NR3C1 2 GO:0090025 regulation of monocyte chemotaxis 2/313 29/18722 0.084200885220838 0.275152592305348 SERPINE1/LGMN 2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 2/313 29/18722 0.084200885220838 0.275152592305348 MIF/CLU 2 GO:0003300 cardiac muscle hypertrophy 4/313 99/18722 0.0844289043377445 0.275189074326878 TNFRSF1A/PARP1/ERRFI1/RGS2 4 GO:0030838 positive regulation of actin filament polymerization 4/313 99/18722 0.0844289043377445 0.275189074326878 PFN1/RHOA/SCIN/IQGAP2 4 GO:0051153 regulation of striated muscle cell differentiation 4/313 99/18722 0.0844289043377445 0.275189074326878 MORF4L2/YBX1/BHLHE41/RGS2 4 GO:0032623 interleukin-2 production 3/313 62/18722 0.0852759762884811 0.275824674367245 ANXA1/EZR/PDE4B 3 GO:0032663 regulation of interleukin-2 production 3/313 62/18722 0.0852759762884811 0.275824674367245 ANXA1/EZR/PDE4B 3 GO:0032731 positive regulation of interleukin-1 beta production 3/313 62/18722 0.0852759762884811 0.275824674367245 ISL1/HSPB1/EGR1 3 GO:0046173 polyol biosynthetic process 3/313 62/18722 0.0852759762884811 0.275824674367245 AKR1B1/ISYNA1/PGP 3 GO:0046847 filopodium assembly 3/313 62/18722 0.0852759762884811 0.275824674367245 RAB17/EZR/CLN3 3 GO:0048488 synaptic vesicle endocytosis 3/313 62/18722 0.0852759762884811 0.275824674367245 ACTG1/CALM1/ACTB 3 GO:0070265 necrotic cell death 3/313 62/18722 0.0852759762884811 0.275824674367245 CAV1/PYGL/YBX3 3 GO:0140238 presynaptic endocytosis 3/313 62/18722 0.0852759762884811 0.275824674367245 ACTG1/CALM1/ACTB 3 GO:1903078 positive regulation of protein localization to plasma membrane 3/313 62/18722 0.0852759762884811 0.275824674367245 EZR/ITGB1/CLN3 3 GO:0019058 viral life cycle 9/313 317/18722 0.0858928024087451 0.277367680041464 CAV1/DDX5/LY6E/BSG/CAV2/ITGB1/HSPA1A/HACD3/TOP2A 9 GO:0051495 positive regulation of cytoskeleton organization 7/313 226/18722 0.0858987377906188 0.277367680041464 PFN1/RHOA/SCIN/S100A10/HSPA1A/TPM1/IQGAP2 7 GO:0007292 female gamete generation 5/313 140/18722 0.0861215934679747 0.277851615536085 LGR5/ADAMTS1/TOP2A/CCNB1/RGS2 5 GO:0055074 calcium ion homeostasis 12/313 460/18722 0.0864861445508416 0.278791492214271 CAV1/STC2/GSTO1/ATP2B1/SRI/CAV2/HERPUD1/TMBIM6/CALM1/CLN3/GJA1/MCOLN3 12 GO:0044728 DNA methylation or demethylation 4/313 100/18722 0.0868512908640687 0.279495236111166 MBD3/FOS/PARP1/DNMT3A 4 GO:0046545 development of primary female sexual characteristics 4/313 100/18722 0.0868512908640687 0.279495236111166 CYP19A1/IDH1/CEBPB/ADAMTS1 4 GO:0007411 axon guidance 7/313 227/18722 0.0874378173209463 0.280907823241217 EFNB1/NRP2/BSG/LAMC2/SEMA6D/ISL1/B3GNT2 7 GO:0098657 import into cell 7/313 227/18722 0.0874378173209463 0.280907823241217 SLC7A5/SLC27A2/ITGB1/SLC43A2/ACTB/SLC2A1/RGS2 7 GO:0006119 oxidative phosphorylation 5/313 141/18722 0.0881361455804332 0.282912568486264 UQCRB/COX4I1/RHOA/NDUFB1/CCNB1 5 GO:0046902 regulation of mitochondrial membrane permeability 3/313 63/18722 0.088484637932671 0.283091049790166 PMAIP1/HSPA1A/NMT1 3 GO:0097485 neuron projection guidance 7/313 228/18722 0.0889925263935972 0.283091049790166 EFNB1/NRP2/BSG/LAMC2/SEMA6D/ISL1/B3GNT2 7 GO:0000132 establishment of mitotic spindle orientation 2/313 30/18722 0.0892538845688477 0.283091049790166 ITGB1/GJA1 2 GO:0010453 regulation of cell fate commitment 2/313 30/18722 0.0892538845688477 0.283091049790166 LMO4/HES1 2 GO:0019674 NAD metabolic process 2/313 30/18722 0.0892538845688477 0.283091049790166 LDHA/ENO1 2 GO:0031365 N-terminal protein amino acid modification 2/313 30/18722 0.0892538845688477 0.283091049790166 SOX4/NMT1 2 GO:0031571 mitotic G1 DNA damage checkpoint signaling 2/313 30/18722 0.0892538845688477 0.283091049790166 SOX4/PLK2 2 GO:0044030 regulation of DNA methylation 2/313 30/18722 0.0892538845688477 0.283091049790166 MBD3/PARP1 2 GO:0044788 modulation by host of viral process 2/313 30/18722 0.0892538845688477 0.283091049790166 CAV2/CFL1 2 GO:0045070 positive regulation of viral genome replication 2/313 30/18722 0.0892538845688477 0.283091049790166 HACD3/TOP2A 2 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway 2/313 30/18722 0.0892538845688477 0.283091049790166 PHPT1/EZR 2 GO:0060674 placenta blood vessel development 2/313 30/18722 0.0892538845688477 0.283091049790166 ITGB8/HES1 2 GO:0090151 establishment of protein localization to mitochondrial membrane 2/313 30/18722 0.0892538845688477 0.283091049790166 CALM1/NMT1 2 GO:1903579 negative regulation of ATP metabolic process 2/313 30/18722 0.0892538845688477 0.283091049790166 RHOA/PARP1 2 GO:0042102 positive regulation of T cell proliferation 4/313 101/18722 0.0893071580766979 0.283091049790166 IGF2/EFNB1/ANXA1/HES1 4 GO:0009416 response to light stimulus 9/313 320/18722 0.0897650871284604 0.284069565002534 RDH13/GPX1/FOS/ITGB1/DYNLRB1/PARP1/NMT1/MAP3K4/ID2 9 GO:0071496 cellular response to external stimulus 9/313 320/18722 0.0897650871284604 0.284069565002534 PMAIP1/FOS/ATP2B1/JUN/TNFRSF1A/STK24/GJA1/TMEM150C/SLC2A1 9 GO:0050729 positive regulation of inflammatory response 5/313 142/18722 0.0901751483824809 0.284893601570211 NEAT1/TNFRSF1A/SERPINE1/CTSC/CEBPB 5 GO:2000045 regulation of G1/S transition of mitotic cell cycle 5/313 142/18722 0.0901751483824809 0.284893601570211 ANXA1/SOX4/ADAMTS1/PLK2/ID2 5 GO:0071356 cellular response to tumor necrosis factor 7/313 229/18722 0.0905628353138141 0.285881189087637 KRT8/KRT18/YBX3/TNFRSF1A/TMSB4X/HSPA1A/EIF5A 7 GO:0045670 regulation of osteoclast differentiation 3/313 64/18722 0.0917434451782246 0.288816652646014 FBN1/FOS/CEBPB 3 GO:0098930 axonal transport 3/313 64/18722 0.0917434451782246 0.288816652646014 ARMCX3/DST/HSPB1 3 GO:0001841 neural tube formation 4/313 102/18722 0.0917962042820271 0.288816652646014 LMO4/PFN1/SOX4/BRD2 4 GO:0014897 striated muscle hypertrophy 4/313 102/18722 0.0917962042820271 0.288816652646014 TNFRSF1A/PARP1/ERRFI1/RGS2 4 GO:0030593 neutrophil chemotaxis 4/313 103/18722 0.0943181185681264 0.292637250242708 BSG/CSF3R/PDE4B/JAM3 4 GO:0032760 positive regulation of tumor necrosis factor production 4/313 103/18722 0.0943181185681264 0.292637250242708 MIF/ISL1/HSPB1/CLU 4 GO:0010821 regulation of mitochondrion organization 5/313 144/18722 0.0943259830570635 0.292637250242708 PMAIP1/GPX1/HSPA1A/NMT1/CLU 5 GO:0106106 cold-induced thermogenesis 5/313 144/18722 0.0943259830570635 0.292637250242708 PLAC8/CAV1/CEBPB/GJA1/ARRDC3 5 GO:0120161 regulation of cold-induced thermogenesis 5/313 144/18722 0.0943259830570635 0.292637250242708 PLAC8/CAV1/CEBPB/GJA1/ARRDC3 5 GO:0001516 prostaglandin biosynthetic process 2/313 31/18722 0.0943941537425915 0.292637250242708 ANXA1/MIF 2 GO:0007190 activation of adenylate cyclase activity 2/313 31/18722 0.0943941537425915 0.292637250242708 LGR5/CALM1 2 GO:0044819 mitotic G1/S transition checkpoint signaling 2/313 31/18722 0.0943941537425915 0.292637250242708 SOX4/PLK2 2 GO:0046457 prostanoid biosynthetic process 2/313 31/18722 0.0943941537425915 0.292637250242708 ANXA1/MIF 2 GO:0048710 regulation of astrocyte differentiation 2/313 31/18722 0.0943941537425915 0.292637250242708 ID2/HES1 2 GO:0051443 positive regulation of ubiquitin-protein transferase activity 2/313 31/18722 0.0943941537425915 0.292637250242708 CDC20/ARRDC3 2 GO:0055022 negative regulation of cardiac muscle tissue growth 2/313 31/18722 0.0943941537425915 0.292637250242708 GJA1/RGS2 2 GO:0060045 positive regulation of cardiac muscle cell proliferation 2/313 31/18722 0.0943941537425915 0.292637250242708 TGFBR3/CCNB1 2 GO:0060055 angiogenesis involved in wound healing 2/313 31/18722 0.0943941537425915 0.292637250242708 GPX1/SERPINE1 2 GO:0061099 negative regulation of protein tyrosine kinase activity 2/313 31/18722 0.0943941537425915 0.292637250242708 CAV1/ERRFI1 2 GO:0061117 negative regulation of heart growth 2/313 31/18722 0.0943941537425915 0.292637250242708 GJA1/RGS2 2 GO:0070633 transepithelial transport 2/313 31/18722 0.0943941537425915 0.292637250242708 ACTG1/ACTB 2 GO:1901797 negative regulation of signal transduction by p53 class mediator 2/313 31/18722 0.0943941537425915 0.292637250242708 MIF/PTTG1IP 2 GO:0007159 leukocyte cell-cell adhesion 10/313 371/18722 0.0946556098409137 0.293209037155703 IGF2/CAV1/EFNB1/ANXA1/SOX4/EZR/RHOA/CEBPB/ITGB1/HES1 10 GO:0010965 regulation of mitotic sister chromatid separation 3/313 65/18722 0.0950514840215909 0.293480129497321 NEK6/PTTG1/CCNB1 3 GO:0043489 RNA stabilization 3/313 65/18722 0.0950514840215909 0.293480129497321 YBX3/FUS/YBX1 3 GO:0048524 positive regulation of viral process 3/313 65/18722 0.0950514840215909 0.293480129497321 CAV2/HACD3/TOP2A 3 GO:0071677 positive regulation of mononuclear cell migration 3/313 65/18722 0.0950514840215909 0.293480129497321 SERPINE1/RHOA/LGMN 3 GO:0014896 muscle hypertrophy 4/313 104/18722 0.0968725811115407 0.298618555701729 TNFRSF1A/PARP1/ERRFI1/RGS2 4 GO:0060419 heart growth 4/313 104/18722 0.0968725811115407 0.298618555701729 GJA1/TGFBR3/CCNB1/RGS2 4 GO:1902105 regulation of leukocyte differentiation 8/313 279/18722 0.0973919582326957 0.299976686886628 FBN1/ANXA1/FOS/JUN/SOX4/RHOA/CEBPB/ID2 8 GO:0009060 aerobic respiration 6/313 189/18722 0.0980956478488518 0.301899863670638 IDH1/UQCRB/COX4I1/RHOA/NDUFB1/CCNB1 6 GO:0045600 positive regulation of fat cell differentiation 3/313 66/18722 0.0984078294954381 0.302371756972666 ADIRF/CEBPB/ID2 3 GO:0050918 positive chemotaxis 3/313 66/18722 0.0984078294954381 0.302371756972666 MIF/VEGFB/PGF 3 GO:0021700 developmental maturation 8/313 280/18722 0.098889766011778 0.303607531618418 CD63/PFN1/RHOA/AKR1B1/CDC20/FERMT1/CCNB1/HES1 8 GO:2001022 positive regulation of response to DNA damage stimulus 4/313 105/18722 0.0994592634819322 0.303880917804837 DDX5/PMAIP1/FUS/PARP1 4 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 2/313 32/18722 0.0996173851905533 0.303880917804837 TGFBR3/FERMT1 2 GO:0051497 negative regulation of stress fiber assembly 2/313 32/18722 0.0996173851905533 0.303880917804837 PFN1/STMN1 2 GO:0060323 head morphogenesis 2/313 32/18722 0.0996173851905533 0.303880917804837 CRISPLD1/ANKRD11 2 GO:0060914 heart formation 2/313 32/18722 0.0996173851905533 0.303880917804837 ISL1/HES1 2 GO:0097345 mitochondrial outer membrane permeabilization 2/313 32/18722 0.0996173851905533 0.303880917804837 HSPA1A/NMT1 2 GO:1901185 negative regulation of ERBB signaling pathway 2/313 32/18722 0.0996173851905533 0.303880917804837 ERRFI1/LGMN 2 GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 2/313 32/18722 0.0996173851905533 0.303880917804837 TGFBR3/FERMT1 2 GO:0009566 fertilization 6/313 190/18722 0.0999591452115292 0.30467931610912 ALDOA/YBX3/LY6K/CLIC4/MYH9/SPESP1 6 GO:0045930 negative regulation of mitotic cell cycle 7/313 235/18722 0.100310323685506 0.305505121816577 TIMP2/BTG3/SOX4/PPP1R10/BTG2/PLK2/CCNB1 7 GO:0030111 regulation of Wnt signaling pathway 9/313 328/18722 0.100588680707534 0.306107999563215 CAV1/WLS/TLE4/ISL1/SOX4/LGR5/CTNND1/EGR1/FERMT1 9 GO:0006879 cellular iron ion homeostasis 3/313 67/18722 0.101811546738024 0.308841879228412 FTL/FTH1/SRI 3 GO:0010517 regulation of phospholipase activity 3/313 67/18722 0.101811546738024 0.308841879228412 ANXA1/FLT1/RGS2 3 GO:0032890 regulation of organic acid transport 3/313 67/18722 0.101811546738024 0.308841879228412 ITGB1/SLC43A2/RGS2 3 GO:0051306 mitotic sister chromatid separation 3/313 67/18722 0.101811546738024 0.308841879228412 NEK6/PTTG1/CCNB1 3 GO:0090068 positive regulation of cell cycle process 7/313 236/18722 0.101988801389561 0.308911204126642 IGF2/ANXA1/INSR/RHOA/PPP1R10/ADAMTS1/CCNB1 7 GO:0006766 vitamin metabolic process 4/313 106/18722 0.102077828944396 0.308911204126642 CYP11A1/GSTO1/SLC2A1/LGMN 4 GO:0090263 positive regulation of canonical Wnt signaling pathway 4/313 106/18722 0.102077828944396 0.308911204126642 CAV1/WLS/SOX4/LGR5 4 GO:0050905 neuromuscular process 5/313 148/18722 0.102915002106013 0.310703737523864 GSTO1/C12orf57/UBA5/CLN3/TMEM150C 5 GO:0070507 regulation of microtubule cytoskeleton organization 5/313 148/18722 0.102915002106013 0.310703737523864 STMN3/CCSAP/RHOA/HSPA1A/STMN1 5 GO:1903900 regulation of viral life cycle 5/313 148/18722 0.102915002106013 0.310703737523864 DDX5/LY6E/CAV2/HACD3/TOP2A 5 GO:1901617 organic hydroxy compound biosynthetic process 7/313 237/18722 0.103682556715493 0.312704615927238 HSD17B1/SLC27A2/DHCR24/AKR1B1/ISYNA1/CYB5R1/PGP 7 GO:0032872 regulation of stress-activated MAPK cascade 6/313 192/18722 0.103742035701629 0.312704615927238 PAGE4/GADD45B/PRDX1/EZR/PRMT1/MAP3K4 6 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 4/313 107/18722 0.10472793275929 0.313071298070773 MIF/ISL1/HSPB1/CLU 4 GO:0003002 regionalization 9/313 331/18722 0.104833102292102 0.313071298070773 WLS/NRP2/ISL1/FKBP8/BTG2/BHLHE41/TRA2B/TMEM107/HES1 9 GO:0001975 response to amphetamine 2/313 33/18722 0.104919390169975 0.313071298070773 CALM1/RGS2 2 GO:0003382 epithelial cell morphogenesis 2/313 33/18722 0.104919390169975 0.313071298070773 FLNB/CLIC4 2 GO:0010737 protein kinase A signaling 2/313 33/18722 0.104919390169975 0.313071298070773 MIF/EZR 2 GO:0032633 interleukin-4 production 2/313 33/18722 0.104919390169975 0.313071298070773 SLC7A5/CEBPB 2 GO:0032673 regulation of interleukin-4 production 2/313 33/18722 0.104919390169975 0.313071298070773 SLC7A5/CEBPB 2 GO:0045648 positive regulation of erythrocyte differentiation 2/313 33/18722 0.104919390169975 0.313071298070773 PRMT1/HSPA1A 2 GO:0048048 embryonic eye morphogenesis 2/313 33/18722 0.104919390169975 0.313071298070773 FBN1/MFAP5 2 GO:0048333 mesodermal cell differentiation 2/313 33/18722 0.104919390169975 0.313071298070773 ITGB1/GJA1 2 GO:1900181 negative regulation of protein localization to nucleus 2/313 33/18722 0.104919390169975 0.313071298070773 MAGED1/FERMT1 2 GO:1901976 regulation of cell cycle checkpoint 2/313 33/18722 0.104919390169975 0.313071298070773 PPP1R10/CCNB1 2 GO:0030900 forebrain development 10/313 379/18722 0.105007445622367 0.313071298070773 NRP2/ISL1/C12orf57/RHOA/TACC2/BTG2/TRA2B/SLC2A1/ID2/HES1 10 GO:0009988 cell-cell recognition 3/313 68/18722 0.105261692022745 0.313071298070773 ALDOA/LY6K/SPESP1 3 GO:0010812 negative regulation of cell-substrate adhesion 3/313 68/18722 0.105261692022745 0.313071298070773 SERPINE1/FBLN1/RHOA 3 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 3/313 68/18722 0.105261692022745 0.313071298070773 TNFRSF1A/ISL1/HES1 3 GO:0042987 amyloid precursor protein catabolic process 3/313 68/18722 0.105261692022745 0.313071298070773 DHCR24/CLN3/CLU 3 GO:0051403 stress-activated MAPK cascade 7/313 239/18722 0.107115695563925 0.318088496889127 PAGE4/GADD45B/PRDX1/EZR/PRMT1/HACD3/MAP3K4 7 GO:1903039 positive regulation of leukocyte cell-cell adhesion 7/313 239/18722 0.107115695563925 0.318088496889127 IGF2/CAV1/EFNB1/ANXA1/SOX4/RHOA/HES1 7 GO:0070665 positive regulation of leukocyte proliferation 5/313 150/18722 0.107350730744543 0.318463325528949 IGF2/EFNB1/ANXA1/MIF/HES1 5 GO:0034446 substrate adhesion-dependent cell spreading 4/313 108/18722 0.107409222479425 0.318463325528949 FN1/FBLN1/RHOA/S100A10 4 GO:0045665 negative regulation of neuron differentiation 3/313 69/18722 0.108757313749013 0.321958859597582 ISL1/RHOA/HES1 3 GO:1904377 positive regulation of protein localization to cell periphery 3/313 69/18722 0.108757313749013 0.321958859597582 EZR/ITGB1/CLN3 3 GO:0070302 regulation of stress-activated protein kinase signaling cascade 6/313 195/18722 0.109554804358888 0.323744978773942 PAGE4/GADD45B/PRDX1/EZR/PRMT1/MAP3K4 6 GO:0043535 regulation of blood vessel endothelial cell migration 5/313 151/18722 0.10960332290741 0.323744978773942 ANXA1/RHOA/TMSB4X/HSPB1/PLK2 5 GO:0032414 positive regulation of ion transmembrane transporter activity 4/313 109/18722 0.110121338244478 0.323744978773942 GSTO1/TCAF1/TMSB4X/CALM1 4 GO:0002183 cytoplasmic translational initiation 2/313 34/18722 0.110296095999423 0.323744978773942 EIF4H/EIF4B 2 GO:0010922 positive regulation of phosphatase activity 2/313 34/18722 0.110296095999423 0.323744978773942 CALM1/PPP1R15A 2 GO:0032743 positive regulation of interleukin-2 production 2/313 34/18722 0.110296095999423 0.323744978773942 ANXA1/PDE4B 2 GO:0035909 aorta morphogenesis 2/313 34/18722 0.110296095999423 0.323744978773942 SOX4/HES1 2 GO:0043276 anoikis 2/313 34/18722 0.110296095999423 0.323744978773942 CAV1/ITGB1 2 GO:0048741 skeletal muscle fiber development 2/313 34/18722 0.110296095999423 0.323744978773942 GPX1/CAV2 2 GO:0051085 chaperone cofactor-dependent protein refolding 2/313 34/18722 0.110296095999423 0.323744978773942 HSPA1A/DNAJB4 2 GO:2000758 positive regulation of peptidyl-lysine acetylation 2/313 34/18722 0.110296095999423 0.323744978773942 ISL1/SOX4 2 GO:0044843 cell cycle G1/S phase transition 7/313 241/18722 0.110609308666705 0.324414205003194 ANXA1/BACH1/SOX4/ITGB1/ADAMTS1/PLK2/ID2 7 GO:0043393 regulation of protein binding 6/313 196/18722 0.111528938440572 0.326608206648661 CAV1/PHLDA2/TMBIM6/ACTB/TGFBR3/PLK2 6 GO:0071674 mononuclear cell migration 6/313 196/18722 0.111528938440572 0.326608206648661 ANXA1/CD99/SERPINE1/RHOA/FLT1/LGMN 6 GO:0045123 cellular extravasation 3/313 70/18722 0.112297453395566 0.328605999290484 CD99/ITGB1/JAM3 3 GO:0006939 smooth muscle contraction 4/313 110/18722 0.112863913072492 0.329503770756886 CAV1/ATP2B1/RHOA/RGS2 4 GO:0007088 regulation of mitotic nuclear division 4/313 110/18722 0.112863913072492 0.329503770756886 IGF2/CAV2/INSR/CCNB1 4 GO:1905954 positive regulation of lipid localization 4/313 110/18722 0.112863913072492 0.329503770756886 CAV1/PLIN2/CYP19A1/DBI 4 GO:0008380 RNA splicing 11/313 434/18722 0.113295784958213 0.330511151981546 DDX5/FUS/PRMT1/HSPA1A/TMBIM6/YBX1/PRDX6/TRA2B/SCAF11/AHNAK/CTNNBL1 11 GO:0016358 dendrite development 7/313 243/18722 0.114162929351035 0.332785813200146 RAB17/LAMC2/CFL1/RHOA/ITGB1/CDC20/PLK2 7 GO:0045860 positive regulation of protein kinase activity 10/313 386/18722 0.114581736180431 0.333751086181254 IGF2/INSR/MAGED1/RHOA/FLT1/CALM1/MAP3K4/EGR1/CLU/CCNB1 10 GO:0015718 monocarboxylic acid transport 4/313 111/18722 0.115636573148338 0.334321448867874 SLC6A8/ANXA1/SLC16A1/MPC2 4 GO:0006739 NADP metabolic process 2/313 35/18722 0.115743543369545 0.334321448867874 IDH1/PGAM1 2 GO:0032232 negative regulation of actin filament bundle assembly 2/313 35/18722 0.115743543369545 0.334321448867874 PFN1/STMN1 2 GO:0032350 regulation of hormone metabolic process 2/313 35/18722 0.115743543369545 0.334321448867874 STC2/EGR1 2 GO:0033280 response to vitamin D 2/313 35/18722 0.115743543369545 0.334321448867874 STC2/ATP2B1 2 GO:0034405 response to fluid shear stress 2/313 35/18722 0.115743543369545 0.334321448867874 TFPI2/GJA1 2 GO:0040001 establishment of mitotic spindle localization 2/313 35/18722 0.115743543369545 0.334321448867874 ITGB1/GJA1 2 GO:0043243 positive regulation of protein-containing complex disassembly 2/313 35/18722 0.115743543369545 0.334321448867874 INSR/EIF5A 2 GO:0060236 regulation of mitotic spindle organization 2/313 35/18722 0.115743543369545 0.334321448867874 CCSAP/HSPA1A 2 GO:0086005 ventricular cardiac muscle cell action potential 2/313 35/18722 0.115743543369545 0.334321448867874 CAV1/DSP 2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 2/313 35/18722 0.115743543369545 0.334321448867874 ANXA1/PLK2 2 GO:0000281 mitotic cytokinesis 3/313 71/18722 0.115881146437312 0.334349093228721 RHOA/STMN1/RHOB 3 GO:0007389 pattern specification process 11/313 436/18722 0.115928763609643 0.334349093228721 EFNB1/WLS/NRP2/GALNT11/ISL1/FKBP8/BTG2/BHLHE41/TRA2B/TMEM107/HES1 11 GO:0072503 cellular divalent inorganic cation homeostasis 12/313 486/18722 0.116460683011888 0.335628932798076 CAV1/STC2/GSTO1/ATP2B1/SRI/CAV2/HERPUD1/TMBIM6/CALM1/CLN3/GJA1/MCOLN3 12 GO:0042098 T cell proliferation 6/313 199/18722 0.117559577501105 0.338539570005073 IGF2/EFNB1/ANXA1/CD151/CEBPB/HES1 6 GO:0001676 long-chain fatty acid metabolic process 4/313 112/18722 0.118438938109026 0.340556674759109 CYP2J2/GPX1/SLC27A2/GPX4 4 GO:0043406 positive regulation of MAP kinase activity 4/313 112/18722 0.118438938109026 0.340556674759109 INSR/MAGED1/FLT1/MAP3K4 4 GO:0001707 mesoderm formation 3/313 72/18722 0.119507423226749 0.34207876708589 WLS/ITGB1/GJA1 3 GO:0032729 positive regulation of interferon-gamma production 3/313 72/18722 0.119507423226749 0.34207876708589 SLC7A5/ISL1/PDE4B 3 GO:0033045 regulation of sister chromatid segregation 3/313 72/18722 0.119507423226749 0.34207876708589 NEK6/PTTG1/CCNB1 3 GO:0042246 tissue regeneration 3/313 72/18722 0.119507423226749 0.34207876708589 ANXA1/GPX1/CCNB1 3 GO:0043903 regulation of biological process involved in symbiotic interaction 3/313 72/18722 0.119507423226749 0.34207876708589 CAV1/LY6E/CAV2 3 GO:1905818 regulation of chromosome separation 3/313 72/18722 0.119507423226749 0.34207876708589 NEK6/PTTG1/CCNB1 3 GO:0000280 nuclear division 11/313 439/18722 0.119943284977627 0.343068434192206 IGF2/NEK6/CCSAP/CAV2/INSR/RHOA/PTTG1/HSPA1A/CDC20/TOP2A/CCNB1 11 GO:0051656 establishment of organelle localization 10/313 390/18722 0.120266865072349 0.343735702200026 ARMCX3/RAB17/PDCD6/CFL1/EZR/MYH9/ITGB1/CLN3/GJA1/CCNB1 10 GO:0002691 regulation of cellular extravasation 2/313 36/18722 0.121257883710845 0.344535265214287 CD99/JAM3 2 GO:0003230 cardiac atrium development 2/313 36/18722 0.121257883710845 0.344535265214287 ISL1/SOX4 2 GO:0009225 nucleotide-sugar metabolic process 2/313 36/18722 0.121257883710845 0.344535265214287 UGP2/EXTL2 2 GO:0010762 regulation of fibroblast migration 2/313 36/18722 0.121257883710845 0.344535265214287 ITGB1/CLN3 2 GO:0030224 monocyte differentiation 2/313 36/18722 0.121257883710845 0.344535265214287 JUN/MYH9 2 GO:0045652 regulation of megakaryocyte differentiation 2/313 36/18722 0.121257883710845 0.344535265214287 PRMT1/SCIN 2 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 2/313 36/18722 0.121257883710845 0.344535265214287 MIF/CLU 2 GO:0044106 cellular amine metabolic process 4/313 113/18722 0.121270621325754 0.344535265214287 LY6E/OAZ1/AKR1B1/CLN3 4 GO:0032732 positive regulation of interleukin-1 production 3/313 73/18722 0.123175309841008 0.349164858201578 ISL1/HSPB1/EGR1 3 GO:0072089 stem cell proliferation 3/313 73/18722 0.123175309841008 0.349164858201578 FBLN1/GJA1/FERMT1 3 GO:1904427 positive regulation of calcium ion transmembrane transport 3/313 73/18722 0.123175309841008 0.349164858201578 GSTO1/SRI/CALM1 3 GO:0001837 epithelial to mesenchymal transition 5/313 157/18722 0.123593711949252 0.349829934119557 DDX5/PDCD6/ISL1/HNRNPAB/TGFBR3 5 GO:1990845 adaptive thermogenesis 5/313 157/18722 0.123593711949252 0.349829934119557 PLAC8/CAV1/CEBPB/GJA1/ARRDC3 5 GO:0007041 lysosomal transport 4/313 114/18722 0.124131230182598 0.350050069114927 HSPA1A/CLN3/RHOB/CLU 4 GO:0019751 polyol metabolic process 4/313 114/18722 0.124131230182598 0.350050069114927 TPI1/AKR1B1/ISYNA1/PGP 4 GO:0021987 cerebral cortex development 4/313 114/18722 0.124131230182598 0.350050069114927 RHOA/TACC2/TRA2B/SLC2A1 4 GO:0022904 respiratory electron transport chain 4/313 114/18722 0.124131230182598 0.350050069114927 UQCRB/COX4I1/NDUFB1/CCNB1 4 GO:0046660 female sex differentiation 4/313 114/18722 0.124131230182598 0.350050069114927 CYP19A1/IDH1/CEBPB/ADAMTS1 4 GO:0045926 negative regulation of growth 7/313 249/18722 0.125178657775545 0.352742524168393 PLAC8/ENO1/SEMA6D/HSPA1A/GJA1/LGMN/RGS2 7 GO:0006643 membrane lipid metabolic process 6/313 203/18722 0.125848948290503 0.353484308992027 ORMDL1/SERINC5/TECR/HACD3/SPTSSA/ITGB8 6 GO:0014904 myotube cell development 2/313 37/18722 0.12683537661733 0.353484308992027 GPX1/CAV2 2 GO:0016202 regulation of striated muscle tissue development 2/313 37/18722 0.12683537661733 0.353484308992027 IGF2/YBX3 2 GO:0030513 positive regulation of BMP signaling pathway 2/313 37/18722 0.12683537661733 0.353484308992027 FKBP8/HES1 2 GO:0032885 regulation of polysaccharide biosynthetic process 2/313 37/18722 0.12683537661733 0.353484308992027 IGF2/INSR 2 GO:0042178 xenobiotic catabolic process 2/313 37/18722 0.12683537661733 0.353484308992027 CYP2J2/GSTO1 2 GO:0043403 skeletal muscle tissue regeneration 2/313 37/18722 0.12683537661733 0.353484308992027 ANXA1/GPX1 2 GO:0045730 respiratory burst 2/313 37/18722 0.12683537661733 0.353484308992027 PGAM1/INSR 2 GO:0048846 axon extension involved in axon guidance 2/313 37/18722 0.12683537661733 0.353484308992027 NRP2/SEMA6D 2 GO:0051294 establishment of spindle orientation 2/313 37/18722 0.12683537661733 0.353484308992027 ITGB1/GJA1 2 GO:1902284 neuron projection extension involved in neuron projection guidance 2/313 37/18722 0.12683537661733 0.353484308992027 NRP2/SEMA6D 2 GO:1905332 positive regulation of morphogenesis of an epithelium 2/313 37/18722 0.12683537661733 0.353484308992027 MAGED1/GJA1 2 GO:0048332 mesoderm morphogenesis 3/313 74/18722 0.126883828895521 0.353484308992027 WLS/ITGB1/GJA1 3 GO:0051881 regulation of mitochondrial membrane potential 3/313 74/18722 0.126883828895521 0.353484308992027 PMAIP1/CLIC1/PARP1 3 GO:0070972 protein localization to endoplasmic reticulum 3/313 74/18722 0.126883828895521 0.353484308992027 HERPUD1/GJA1/PPP1R15A 3 GO:0051209 release of sequestered calcium ion into cytosol 4/313 115/18722 0.127020366351745 0.353484308992027 GSTO1/SRI/CALM1/MCOLN3 4 GO:1901989 positive regulation of cell cycle phase transition 4/313 115/18722 0.127020366351745 0.353484308992027 ANXA1/PPP1R10/ADAMTS1/CCNB1 4 GO:0031647 regulation of protein stability 8/313 298/18722 0.128040146113519 0.355651338420037 GAPDH/RPL23/PFN1/AAK1/SOX4/HSPA1A/CTNND1/CLU 8 GO:0048511 rhythmic process 8/313 298/18722 0.128040146113519 0.355651338420037 DDX5/JUN/MAGED1/BHLHE41/EGR1/ADAMTS1/ID2/TOP2A 8 GO:1901361 organic cyclic compound catabolic process 12/313 495/18722 0.128079323607531 0.355651338420037 DDX5/CYP19A1/YBX3/FUS/PKP3/BLVRA/PDE4B/HSPA1A/YBX1/SSB/BTG2/KCNQ1OT1 12 GO:0046700 heterocycle catabolic process 11/313 445/18722 0.128204786133961 0.355740248405241 DDX5/YBX3/FUS/PKP3/BLVRA/PDE4B/HSPA1A/YBX1/SSB/BTG2/KCNQ1OT1 11 GO:0007006 mitochondrial membrane organization 4/313 116/18722 0.129937626065184 0.359239319121391 PMAIP1/HSPA1A/CALM1/NMT1 4 GO:0008286 insulin receptor signaling pathway 4/313 116/18722 0.129937626065184 0.359239319121391 IGF2/CAV2/INSR/PTPRA 4 GO:0035967 cellular response to topologically incorrect protein 4/313 116/18722 0.129937626065184 0.359239319121391 HERPUD1/HSPA1A/TMBIM6/PPP1R15A 4 GO:0043200 response to amino acid 4/313 116/18722 0.129937626065184 0.359239319121391 RHOA/CEBPB/TMBIM6/DNMT3A 4 GO:0051283 negative regulation of sequestering of calcium ion 4/313 116/18722 0.129937626065184 0.359239319121391 GSTO1/SRI/CALM1/MCOLN3 4 GO:0006094 gluconeogenesis 3/313 75/18722 0.130632000325285 0.359332388178007 TPI1/PGK1/PGP 3 GO:0008088 axo-dendritic transport 3/313 75/18722 0.130632000325285 0.359332388178007 ARMCX3/DST/HSPB1 3 GO:0036465 synaptic vesicle recycling 3/313 75/18722 0.130632000325285 0.359332388178007 ACTG1/CALM1/ACTB 3 GO:0045913 positive regulation of carbohydrate metabolic process 3/313 75/18722 0.130632000325285 0.359332388178007 IGF2/PMAIP1/INSR 3 GO:0048662 negative regulation of smooth muscle cell proliferation 3/313 75/18722 0.130632000325285 0.359332388178007 IGFBP3/RHOA/TPM1 3 GO:0061333 renal tubule morphogenesis 3/313 75/18722 0.130632000325285 0.359332388178007 MAGED1/LGR5/HES1 3 GO:2001259 positive regulation of cation channel activity 3/313 75/18722 0.130632000325285 0.359332388178007 GSTO1/TMSB4X/CALM1 3 GO:0006869 lipid transport 10/313 398/18722 0.132097364180982 0.36282185506901 CROT/CAV1/PLIN2/ANXA1/CYP19A1/SLC27A2/DBI/CLN3/CLU/SLC2A1 10 GO:0010876 lipid localization 11/313 448/18722 0.132450685615652 0.36282185506901 CROT/CAV1/PLIN2/ANXA1/CYP19A1/MEST/SLC27A2/DBI/CLN3/CLU/SLC2A1 11 GO:0008210 estrogen metabolic process 2/313 38/18722 0.132472387324908 0.36282185506901 CYP19A1/HSD17B1 2 GO:0042491 inner ear auditory receptor cell differentiation 2/313 38/18722 0.132472387324908 0.36282185506901 MCOLN3/HES1 2 GO:0097242 amyloid-beta clearance 2/313 38/18722 0.132472387324908 0.36282185506901 INSR/CLU 2 GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 2/313 38/18722 0.132472387324908 0.36282185506901 HSPA1A/NMT1 2 GO:0034612 response to tumor necrosis factor 7/313 253/18722 0.132812441910398 0.363491708377342 KRT8/KRT18/YBX3/TNFRSF1A/TMSB4X/HSPA1A/EIF5A 7 GO:0014855 striated muscle cell proliferation 3/313 76/18722 0.134418842134699 0.366833356277275 GJA1/TGFBR3/CCNB1 3 GO:0021536 diencephalon development 3/313 76/18722 0.134418842134699 0.366833356277275 NRP2/ISL1/HES1 3 GO:0031100 animal organ regeneration 3/313 76/18722 0.134418842134699 0.366833356277275 PGF/CEBPB/TGFBR3 3 GO:0140115 export across plasma membrane 3/313 76/18722 0.134418842134699 0.366833356277275 ATP2B1/CALM1/GJA1 3 GO:0009165 nucleotide biosynthetic process 7/313 254/18722 0.134756414600009 0.367491167895584 ALDOA/ENO1/SLC26A2/TMSB4X/PARP1/MPC2/TECR 7 GO:0051494 negative regulation of cytoskeleton organization 5/313 162/18722 0.135852679722184 0.368901220302034 PFN1/TMSB4X/SCIN/STMN1/KANK4 5 GO:0007613 memory 4/313 118/18722 0.135854875456646 0.368901220302034 INSR/CEBPB/PLK2/LGMN 4 GO:0009308 amine metabolic process 4/313 118/18722 0.135854875456646 0.368901220302034 LY6E/OAZ1/AKR1B1/CLN3 4 GO:0045446 endothelial cell differentiation 4/313 118/18722 0.135854875456646 0.368901220302034 GPX1/TNFRSF1A/CLIC4/EZR 4 GO:0051282 regulation of sequestering of calcium ion 4/313 118/18722 0.135854875456646 0.368901220302034 GSTO1/SRI/CALM1/MCOLN3 4 GO:1903313 positive regulation of mRNA metabolic process 4/313 118/18722 0.135854875456646 0.368901220302034 BTG2/PRDX6/TRA2B/CCNB1 4 GO:1901215 negative regulation of neuron death 6/313 208/18722 0.136599505509634 0.370658815021509 ISL1/RHOA/CEBPB/BTG2/CLN3/LGMN 6 GO:0044270 cellular nitrogen compound catabolic process 11/313 451/18722 0.136772535921541 0.370863991633408 DDX5/YBX3/FUS/PKP3/BLVRA/PDE4B/HSPA1A/YBX1/SSB/BTG2/KCNQ1OT1 11 GO:0031507 heterochromatin assembly 2/313 39/18722 0.138165384243433 0.371675504125666 MBD3/DNMT3A 2 GO:0032506 cytokinetic process 2/313 39/18722 0.138165384243433 0.371675504125666 MYH9/RHOA 2 GO:0045823 positive regulation of heart contraction 2/313 39/18722 0.138165384243433 0.371675504125666 TPM1/RGS2 2 GO:0046621 negative regulation of organ growth 2/313 39/18722 0.138165384243433 0.371675504125666 GJA1/RGS2 2 GO:0051084 'de novo' posttranslational protein folding 2/313 39/18722 0.138165384243433 0.371675504125666 HSPA1A/DNAJB4 2 GO:0071548 response to dexamethasone 2/313 39/18722 0.138165384243433 0.371675504125666 ERRFI1/NR3C1 2 GO:0090224 regulation of spindle organization 2/313 39/18722 0.138165384243433 0.371675504125666 CCSAP/HSPA1A 2 GO:1901021 positive regulation of calcium ion transmembrane transporter activity 2/313 39/18722 0.138165384243433 0.371675504125666 GSTO1/CALM1 2 GO:1901861 regulation of muscle tissue development 2/313 39/18722 0.138165384243433 0.371675504125666 IGF2/YBX3 2 GO:2000249 regulation of actin cytoskeleton reorganization 2/313 39/18722 0.138165384243433 0.371675504125666 PHPT1/IQGAP2 2 GO:0021675 nerve development 3/313 77/18722 0.138243371116875 0.371675504125666 NRP2/ISL1/HES1 3 GO:0140056 organelle localization by membrane tethering 3/313 77/18722 0.138243371116875 0.371675504125666 CAV2/CALM1/CLN3 3 GO:0006633 fatty acid biosynthetic process 5/313 163/18722 0.138367459141472 0.371746589238944 ANXA1/MIF/GPX4/TECR/HACD3 5 GO:1901293 nucleoside phosphate biosynthetic process 7/313 256/18722 0.138686399262562 0.372340706623819 ALDOA/ENO1/SLC26A2/TMSB4X/PARP1/MPC2/TECR 7 GO:0050792 regulation of viral process 5/313 164/18722 0.140902718945773 0.378024419328088 DDX5/LY6E/CAV2/HACD3/TOP2A 5 GO:0007623 circadian rhythm 6/313 210/18722 0.14101744602995 0.378065786645085 JUN/MAGED1/BHLHE41/EGR1/ID2/TOP2A 6 GO:0006304 DNA modification 4/313 120/18722 0.141879649502825 0.379308866332341 MBD3/FOS/PARP1/DNMT3A 4 GO:0032411 positive regulation of transporter activity 4/313 120/18722 0.141879649502825 0.379308866332341 GSTO1/TCAF1/TMSB4X/CALM1 4 GO:0048675 axon extension 4/313 120/18722 0.141879649502825 0.379308866332341 FN1/NRP2/SEMA6D/ITGB1 4 GO:0051897 positive regulation of protein kinase B signaling 4/313 120/18722 0.141879649502825 0.379308866332341 IGF2/GPX1/INSR/ITGB1 4 GO:0043297 apical junction assembly 3/313 78/18722 0.142104603543364 0.379377437369977 RHOA/GJA1/CLDN7 3 GO:0090049 regulation of cell migration involved in sprouting angiogenesis 3/313 78/18722 0.142104603543364 0.379377437369977 ANXA1/RHOA/PLK2 3 GO:0045165 cell fate commitment 7/313 258/18722 0.142671844183787 0.380624884938806 LMO4/ISL1/FKBP8/RHOA/ITGB1/ID2/HES1 7 GO:0050807 regulation of synapse organization 6/313 211/18722 0.143251103241699 0.38099369639279 NRP2/RAB17/CFL1/RHOA/CLN3/CDC20 6 GO:0007339 binding of sperm to zona pellucida 2/313 40/18722 0.143910936541327 0.38099369639279 ALDOA/LY6K 2 GO:0030866 cortical actin cytoskeleton organization 2/313 40/18722 0.143910936541327 0.38099369639279 EZR/EPB41L3 2 GO:0043001 Golgi to plasma membrane protein transport 2/313 40/18722 0.143910936541327 0.38099369639279 KRT18/CLN3 2 GO:0045429 positive regulation of nitric oxide biosynthetic process 2/313 40/18722 0.143910936541327 0.38099369639279 INSR/CLU 2 GO:0071276 cellular response to cadmium ion 2/313 40/18722 0.143910936541327 0.38099369639279 FOS/JUN 2 GO:0071526 semaphorin-plexin signaling pathway 2/313 40/18722 0.143910936541327 0.38099369639279 NRP2/SEMA6D 2 GO:0072210 metanephric nephron development 2/313 40/18722 0.143910936541327 0.38099369639279 EGR1/HES1 2 GO:0097352 autophagosome maturation 2/313 40/18722 0.143910936541327 0.38099369639279 CALM1/CLN3 2 GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 2/313 40/18722 0.143910936541327 0.38099369639279 HSPA1A/NMT1 2 GO:2000781 positive regulation of double-strand break repair 2/313 40/18722 0.143910936541327 0.38099369639279 FUS/PARP1 2 GO:0001704 formation of primary germ layer 4/313 121/18722 0.14493129856704 0.382365525741316 FN1/WLS/ITGB1/GJA1 4 GO:0001838 embryonic epithelial tube formation 4/313 121/18722 0.14493129856704 0.382365525741316 LMO4/PFN1/SOX4/BRD2 4 GO:0043244 regulation of protein-containing complex disassembly 4/313 121/18722 0.14493129856704 0.382365525741316 INSR/SCIN/EIF5A/CLN3 4 GO:0043500 muscle adaptation 4/313 121/18722 0.14493129856704 0.382365525741316 TNFRSF1A/PARP1/ERRFI1/RGS2 4 GO:1904019 epithelial cell apoptotic process 4/313 121/18722 0.14493129856704 0.382365525741316 KRT8/KRT18/SERPINE1/DNMT3A 4 GO:0006469 negative regulation of protein kinase activity 6/313 212/18722 0.145501031683944 0.383602789211063 CAV1/MLLT1/GADD45B/HSPB1/ERRFI1/RGS2 6 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 3/313 79/18722 0.146001555825152 0.384182882773754 FN1/INSR/FLT1 3 GO:0051279 regulation of release of sequestered calcium ion into cytosol 3/313 79/18722 0.146001555825152 0.384182882773754 GSTO1/SRI/CALM1 3 GO:0061013 regulation of mRNA catabolic process 5/313 166/18722 0.146033766298265 0.384182882773754 YBX3/FUS/PKP3/YBX1/BTG2 5 GO:0034655 nucleobase-containing compound catabolic process 10/313 407/18722 0.146124721370212 0.384182882773754 DDX5/YBX3/FUS/PKP3/PDE4B/HSPA1A/YBX1/SSB/BTG2/KCNQ1OT1 10 GO:0001503 ossification 10/313 408/18722 0.147729240072478 0.386783425884552 IGF2/DDX5/RPL38/ATP2B1/SLC26A2/RHOA/CLIC1/CEBPB/TPM4/FHL2 10 GO:0031109 microtubule polymerization or depolymerization 4/313 122/18722 0.148008549073253 0.386783425884552 STMN3/CCSAP/HSPA1A/STMN1 4 GO:0051208 sequestering of calcium ion 4/313 122/18722 0.148008549073253 0.386783425884552 GSTO1/SRI/CALM1/MCOLN3 4 GO:0048634 regulation of muscle organ development 2/313 41/18722 0.149705711781698 0.386783425884552 IGF2/YBX3 2 GO:0050856 regulation of T cell receptor signaling pathway 2/313 41/18722 0.149705711781698 0.386783425884552 PHPT1/EZR 2 GO:0055023 positive regulation of cardiac muscle tissue growth 2/313 41/18722 0.149705711781698 0.386783425884552 TGFBR3/CCNB1 2 GO:1902622 regulation of neutrophil migration 2/313 41/18722 0.149705711781698 0.386783425884552 CD99/JAM3 2 GO:1903524 positive regulation of blood circulation 2/313 41/18722 0.149705711781698 0.386783425884552 TPM1/RGS2 2 GO:1904407 positive regulation of nitric oxide metabolic process 2/313 41/18722 0.149705711781698 0.386783425884552 INSR/CLU 2 GO:0001570 vasculogenesis 3/313 80/18722 0.149933245145804 0.386783425884552 CAV1/ITGB8/TGFBR3 3 GO:0032204 regulation of telomere maintenance 3/313 80/18722 0.149933245145804 0.386783425884552 PPP1R10/PARP1/MAP3K4 3 GO:0072330 monocarboxylic acid biosynthetic process 6/313 214/18722 0.150049128076483 0.386783425884552 ANXA1/MIF/SLC27A2/GPX4/TECR/HACD3 6 GO:0031330 negative regulation of cellular catabolic process 7/313 262/18722 0.150806144887583 0.386783425884552 RPL23/TIMP2/TIMP3/YBX3/FUS/PKP3/YBX1 7 GO:1902806 regulation of cell cycle G1/S phase transition 5/313 168/18722 0.151243963144082 0.386783425884552 ANXA1/SOX4/ADAMTS1/PLK2/ID2 5 GO:0070588 calcium ion transmembrane transport 8/313 312/18722 0.153468045698766 0.386783425884552 C4orf3/GSTO1/ATP2B1/SRI/PDE4B/CALM1/AHNAK/MCOLN3 8 GO:0021543 pallium development 5/313 169/18722 0.153878148434489 0.386783425884552 RHOA/TACC2/BTG2/TRA2B/SLC2A1 5 GO:0021954 central nervous system neuron development 3/313 81/18722 0.153898690067593 0.386783425884552 NRP2/C12orf57/BTG2 3 GO:0044773 mitotic DNA damage checkpoint signaling 3/313 81/18722 0.153898690067593 0.386783425884552 SOX4/PPP1R10/PLK2 3 GO:0060968 regulation of gene silencing 3/313 81/18722 0.153898690067593 0.386783425884552 DDX5/NEAT1/KCNQ1OT1 3 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 7/313 264/18722 0.154953447113622 0.386783425884552 IGF2/CAV1/MIF/TNFRSF1A/ISL1/ERRFI1/HES1 7 GO:0003163 sinoatrial node development 1/313 10/18722 0.155184615988053 0.386783425884552 ISL1 1 GO:0003183 mitral valve morphogenesis 1/313 10/18722 0.155184615988053 0.386783425884552 SOX4 1 GO:0003330 regulation of extracellular matrix constituent secretion 1/313 10/18722 0.155184615988053 0.386783425884552 TNFRSF1A 1 GO:0006735 NADH regeneration 1/313 10/18722 0.155184615988053 0.386783425884552 ENO1 1 GO:0009750 response to fructose 1/313 10/18722 0.155184615988053 0.386783425884552 KRT18 1 GO:0010944 negative regulation of transcription by competitive promoter binding 1/313 10/18722 0.155184615988053 0.386783425884552 BHLHE41 1 GO:0010968 regulation of microtubule nucleation 1/313 10/18722 0.155184615988053 0.386783425884552 HSPA1A 1 GO:0015911 long-chain fatty acid import across plasma membrane 1/313 10/18722 0.155184615988053 0.386783425884552 SLC2A1 1 GO:0017085 response to insecticide 1/313 10/18722 0.155184615988053 0.386783425884552 CCNB1 1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 1/313 10/18722 0.155184615988053 0.386783425884552 P4HA1 1 GO:0019532 oxalate transport 1/313 10/18722 0.155184615988053 0.386783425884552 SLC26A2 1 GO:0021562 vestibulocochlear nerve development 1/313 10/18722 0.155184615988053 0.386783425884552 NRP2 1 GO:0021903 rostrocaudal neural tube patterning 1/313 10/18722 0.155184615988053 0.386783425884552 HES1 1 GO:0021932 hindbrain radial glia guided cell migration 1/313 10/18722 0.155184615988053 0.386783425884552 ITGB1 1 GO:0022400 regulation of rhodopsin mediated signaling pathway 1/313 10/18722 0.155184615988053 0.386783425884552 NMT1 1 GO:0030388 fructose 1,6-bisphosphate metabolic process 1/313 10/18722 0.155184615988053 0.386783425884552 ALDOA 1 GO:0030638 polyketide metabolic process 1/313 10/18722 0.155184615988053 0.386783425884552 AKR1B1 1 GO:0030647 aminoglycoside antibiotic metabolic process 1/313 10/18722 0.155184615988053 0.386783425884552 AKR1B1 1 GO:0030953 astral microtubule organization 1/313 10/18722 0.155184615988053 0.386783425884552 EZR 1 GO:0031125 rRNA 3'-end processing 1/313 10/18722 0.155184615988053 0.386783425884552 RPS21 1 GO:0031340 positive regulation of vesicle fusion 1/313 10/18722 0.155184615988053 0.386783425884552 ANXA1 1 GO:0031642 negative regulation of myelination 1/313 10/18722 0.155184615988053 0.386783425884552 CTSC 1 GO:0031915 positive regulation of synaptic plasticity 1/313 10/18722 0.155184615988053 0.386783425884552 CDC20 1 GO:0035646 endosome to melanosome transport 1/313 10/18722 0.155184615988053 0.386783425884552 CD63 1 GO:0036363 transforming growth factor beta activation 1/313 10/18722 0.155184615988053 0.386783425884552 ITGB8 1 GO:0042996 regulation of Golgi to plasma membrane protein transport 1/313 10/18722 0.155184615988053 0.386783425884552 CLN3 1 GO:0043485 endosome to pigment granule transport 1/313 10/18722 0.155184615988053 0.386783425884552 CD63 1 GO:0044557 relaxation of smooth muscle 1/313 10/18722 0.155184615988053 0.386783425884552 RGS2 1 GO:0044598 doxorubicin metabolic process 1/313 10/18722 0.155184615988053 0.386783425884552 AKR1B1 1 GO:0044848 biological phase 1/313 10/18722 0.155184615988053 0.386783425884552 FERMT1 1 GO:0045625 regulation of T-helper 1 cell differentiation 1/313 10/18722 0.155184615988053 0.386783425884552 ANXA1 1 GO:0045792 negative regulation of cell size 1/313 10/18722 0.155184615988053 0.386783425884552 RHOA 1 GO:0045843 negative regulation of striated muscle tissue development 1/313 10/18722 0.155184615988053 0.386783425884552 YBX3 1 GO:0048241 epinephrine transport 1/313 10/18722 0.155184615988053 0.386783425884552 LY6E 1 GO:0048757 pigment granule maturation 1/313 10/18722 0.155184615988053 0.386783425884552 CD63 1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 1/313 10/18722 0.155184615988053 0.386783425884552 CALM1 1 GO:0051351 positive regulation of ligase activity 1/313 10/18722 0.155184615988053 0.386783425884552 TMSB4X 1 GO:0051660 establishment of centrosome localization 1/313 10/18722 0.155184615988053 0.386783425884552 EZR 1 GO:0051918 negative regulation of fibrinolysis 1/313 10/18722 0.155184615988053 0.386783425884552 SERPINE1 1 GO:0061299 retina vasculature morphogenesis in camera-type eye 1/313 10/18722 0.155184615988053 0.386783425884552 CLIC4 1 GO:0061621 canonical glycolysis 1/313 10/18722 0.155184615988053 0.386783425884552 ENO1 1 GO:0061718 glucose catabolic process to pyruvate 1/313 10/18722 0.155184615988053 0.386783425884552 ENO1 1 GO:0071803 positive regulation of podosome assembly 1/313 10/18722 0.155184615988053 0.386783425884552 RHOA 1 GO:0072124 regulation of glomerular mesangial cell proliferation 1/313 10/18722 0.155184615988053 0.386783425884552 EGR1 1 GO:0072203 cell proliferation involved in metanephros development 1/313 10/18722 0.155184615988053 0.386783425884552 EGR1 1 GO:0097084 vascular associated smooth muscle cell development 1/313 10/18722 0.155184615988053 0.386783425884552 HES1 1 GO:0098903 regulation of membrane repolarization during action potential 1/313 10/18722 0.155184615988053 0.386783425884552 CAV1 1 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/313 10/18722 0.155184615988053 0.386783425884552 PMAIP1 1 GO:1902946 protein localization to early endosome 1/313 10/18722 0.155184615988053 0.386783425884552 EZR 1 GO:1903980 positive regulation of microglial cell activation 1/313 10/18722 0.155184615988053 0.386783425884552 CTSC 1 GO:1904668 positive regulation of ubiquitin protein ligase activity 1/313 10/18722 0.155184615988053 0.386783425884552 CDC20 1 GO:1905383 protein localization to presynapse 1/313 10/18722 0.155184615988053 0.386783425884552 HSPB1 1 GO:1905456 regulation of lymphoid progenitor cell differentiation 1/313 10/18722 0.155184615988053 0.386783425884552 HES1 1 GO:1990535 neuron projection maintenance 1/313 10/18722 0.155184615988053 0.386783425884552 INSR 1 GO:2000288 positive regulation of myoblast proliferation 1/313 10/18722 0.155184615988053 0.386783425884552 MALAT1 1 GO:0006040 amino sugar metabolic process 2/313 42/18722 0.155546473608944 0.386783425884552 EXTL2/NPL 2 GO:0007520 myoblast fusion 2/313 42/18722 0.155546473608944 0.386783425884552 ADAM12/MYH9 2 GO:0010939 regulation of necrotic cell death 2/313 42/18722 0.155546473608944 0.386783425884552 CAV1/YBX3 2 GO:0016601 Rac protein signal transduction 2/313 42/18722 0.155546473608944 0.386783425884552 STMN3/HACD3 2 GO:0021879 forebrain neuron differentiation 2/313 42/18722 0.155546473608944 0.386783425884552 NRP2/HES1 2 GO:0032691 negative regulation of interleukin-1 beta production 2/313 42/18722 0.155546473608944 0.386783425884552 SERPINB1/ERRFI1 2 GO:0045687 positive regulation of glial cell differentiation 2/313 42/18722 0.155546473608944 0.386783425884552 ID2/HES1 2 GO:0051452 intracellular pH reduction 2/313 42/18722 0.155546473608944 0.386783425884552 CLIC4/CLN3 2 GO:0007259 receptor signaling pathway via JAK-STAT 5/313 170/18722 0.156531402288841 0.388978491196878 CAV1/TNFRSF1A/ISL1/AKR1B1/HES1 5 GO:0046394 carboxylic acid biosynthetic process 8/313 314/18722 0.157286780896849 0.390600635925834 ANXA1/MIF/SLC27A2/GPX4/SERINC5/TECR/CLN3/HACD3 8 GO:0060395 SMAD protein signal transduction 3/313 82/18722 0.157896911111425 0.391860195959059 FOS/JUN/PARP1 3 GO:0042129 regulation of T cell proliferation 5/313 171/18722 0.159203479265634 0.392084042657056 IGF2/EFNB1/ANXA1/CEBPB/HES1 5 GO:0050803 regulation of synapse structure or activity 6/313 218/18722 0.159334134901222 0.392084042657056 NRP2/RAB17/CFL1/RHOA/CLN3/CDC20 6 GO:0019439 aromatic compound catabolic process 11/313 467/18722 0.161074562597016 0.392084042657056 DDX5/YBX3/FUS/PKP3/BLVRA/PDE4B/HSPA1A/YBX1/SSB/BTG2/KCNQ1OT1 11 GO:0033674 positive regulation of kinase activity 11/313 467/18722 0.161074562597016 0.392084042657056 IGF2/LMO4/INSR/MAGED1/RHOA/FLT1/CALM1/MAP3K4/EGR1/CLU/CCNB1 11 GO:0016053 organic acid biosynthetic process 8/313 316/18722 0.161150361608544 0.392084042657056 ANXA1/MIF/SLC27A2/GPX4/SERINC5/TECR/CLN3/HACD3 8 GO:0001709 cell fate determination 2/313 43/18722 0.161430079484794 0.392084042657056 ISL1/HES1 2 GO:0002861 regulation of inflammatory response to antigenic stimulus 2/313 43/18722 0.161430079484794 0.392084042657056 GPX1/PLK2 2 GO:0006458 'de novo' protein folding 2/313 43/18722 0.161430079484794 0.392084042657056 HSPA1A/DNAJB4 2 GO:0009268 response to pH 2/313 43/18722 0.161430079484794 0.392084042657056 GJA1/LGMN 2 GO:0010171 body morphogenesis 2/313 43/18722 0.161430079484794 0.392084042657056 CRISPLD1/ANKRD11 2 GO:0016266 O-glycan processing 2/313 43/18722 0.161430079484794 0.392084042657056 GALNT11/B3GNT2 2 GO:0021983 pituitary gland development 2/313 43/18722 0.161430079484794 0.392084042657056 ISL1/HES1 2 GO:0033046 negative regulation of sister chromatid segregation 2/313 43/18722 0.161430079484794 0.392084042657056 PTTG1/CCNB1 2 GO:0033048 negative regulation of mitotic sister chromatid segregation 2/313 43/18722 0.161430079484794 0.392084042657056 PTTG1/CCNB1 2 GO:0035794 positive regulation of mitochondrial membrane permeability 2/313 43/18722 0.161430079484794 0.392084042657056 HSPA1A/NMT1 2 GO:0045840 positive regulation of mitotic nuclear division 2/313 43/18722 0.161430079484794 0.392084042657056 IGF2/INSR 2 GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation 2/313 43/18722 0.161430079484794 0.392084042657056 RHOA/TPM1 2 GO:2000816 negative regulation of mitotic sister chromatid separation 2/313 43/18722 0.161430079484794 0.392084042657056 PTTG1/CCNB1 2 GO:0007219 Notch signaling pathway 5/313 172/18722 0.16189413130182 0.392084042657056 KRT19/ANXA4/GALNT11/AAK1/HES1 5 GO:0051899 membrane depolarization 3/313 83/18722 0.16192693131136 0.392084042657056 CAV1/JUN/PARP1 3 GO:0022618 ribonucleoprotein complex assembly 6/313 220/18722 0.164068600844129 0.392084042657056 RPS27/RPL38/RPS28/EIF4H/EIF4B/SCAF11 6 GO:0010469 regulation of signaling receptor activity 5/313 173/18722 0.164603107814586 0.392084042657056 LY6E/PHLDA2/SERPINE1/ITGB1/ERRFI1 5 GO:0070661 leukocyte proliferation 8/313 318/18722 0.165058172211343 0.392084042657056 IGF2/EFNB1/ANXA1/MIF/CD151/CEBPB/CLU/HES1 8 GO:0032370 positive regulation of lipid transport 3/313 84/18722 0.165987776744505 0.392084042657056 CAV1/CYP19A1/DBI 3 GO:0045445 myoblast differentiation 3/313 84/18722 0.165987776744505 0.392084042657056 IGFBP3/DDX5/ISL1 3 GO:0097061 dendritic spine organization 3/313 84/18722 0.165987776744505 0.392084042657056 CFL1/INSR/LGMN 3 GO:0033865 nucleoside bisphosphate metabolic process 4/313 128/18722 0.166985122327591 0.392084042657056 CROT/SLC26A2/MPC2/TECR 4 GO:0033875 ribonucleoside bisphosphate metabolic process 4/313 128/18722 0.166985122327591 0.392084042657056 CROT/SLC26A2/MPC2/TECR 4 GO:0034032 purine nucleoside bisphosphate metabolic process 4/313 128/18722 0.166985122327591 0.392084042657056 CROT/SLC26A2/MPC2/TECR 4 GO:0006775 fat-soluble vitamin metabolic process 2/313 44/18722 0.167353478472818 0.392084042657056 CYP11A1/LGMN 2 GO:0030521 androgen receptor signaling pathway 2/313 44/18722 0.167353478472818 0.392084042657056 DDX5/RHOA 2 GO:0031295 T cell costimulation 2/313 44/18722 0.167353478472818 0.392084042657056 CAV1/EFNB1 2 GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT 2/313 44/18722 0.167353478472818 0.392084042657056 AKR1B1/HES1 2 GO:0050999 regulation of nitric-oxide synthase activity 2/313 44/18722 0.167353478472818 0.392084042657056 CAV1/CALM1 2 GO:0060324 face development 2/313 44/18722 0.167353478472818 0.392084042657056 CRISPLD1/ANKRD11 2 GO:0062208 positive regulation of pattern recognition receptor signaling pathway 2/313 44/18722 0.167353478472818 0.392084042657056 CAV1/HSPA1A 2 GO:0150076 neuroinflammatory response 2/313 44/18722 0.167353478472818 0.392084042657056 CTSC/ITGB1 2 GO:0032102 negative regulation of response to external stimulus 10/313 420/18722 0.167677146763583 0.392084042657056 HTRA1/SERPINB9/GPX1/MIF/TNFRSF1A/SERPINE1/SEMA6D/ISL1/GJA1/PLK2 10 GO:0003093 regulation of glomerular filtration 1/313 11/18722 0.169316040485474 0.392084042657056 GJA1 1 GO:0003139 secondary heart field specification 1/313 11/18722 0.169316040485474 0.392084042657056 ISL1 1 GO:0003174 mitral valve development 1/313 11/18722 0.169316040485474 0.392084042657056 SOX4 1 GO:0006020 inositol metabolic process 1/313 11/18722 0.169316040485474 0.392084042657056 ISYNA1 1 GO:0006054 N-acetylneuraminate metabolic process 1/313 11/18722 0.169316040485474 0.392084042657056 NPL 1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate 1/313 11/18722 0.169316040485474 0.392084042657056 MPC2 1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 1/313 11/18722 0.169316040485474 0.392084042657056 UQCRB 1 GO:0006449 regulation of translational termination 1/313 11/18722 0.169316040485474 0.392084042657056 EIF5A 1 GO:0007042 lysosomal lumen acidification 1/313 11/18722 0.169316040485474 0.392084042657056 CLN3 1 GO:0010269 response to selenium ion 1/313 11/18722 0.169316040485474 0.392084042657056 GPX1 1 GO:0010739 positive regulation of protein kinase A signaling 1/313 11/18722 0.169316040485474 0.392084042657056 MIF 1 GO:0019048 modulation by virus of host process 1/313 11/18722 0.169316040485474 0.392084042657056 INSR 1 GO:0021561 facial nerve development 1/313 11/18722 0.169316040485474 0.392084042657056 NRP2 1 GO:0021604 cranial nerve structural organization 1/313 11/18722 0.169316040485474 0.392084042657056 NRP2 1 GO:0021610 facial nerve morphogenesis 1/313 11/18722 0.169316040485474 0.392084042657056 NRP2 1 GO:0031442 positive regulation of mRNA 3'-end processing 1/313 11/18722 0.169316040485474 0.392084042657056 CCNB1 1 GO:0032276 regulation of gonadotropin secretion 1/313 11/18722 0.169316040485474 0.392084042657056 GJA1 1 GO:0032329 serine transport 1/313 11/18722 0.169316040485474 0.392084042657056 SERINC5 1 GO:0032610 interleukin-1 alpha production 1/313 11/18722 0.169316040485474 0.392084042657056 ISL1 1 GO:0032650 regulation of interleukin-1 alpha production 1/313 11/18722 0.169316040485474 0.392084042657056 ISL1 1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway 1/313 11/18722 0.169316040485474 0.392084042657056 PARP1 1 GO:0033234 negative regulation of protein sumoylation 1/313 11/18722 0.169316040485474 0.392084042657056 HMG20B 1 GO:0033483 gas homeostasis 1/313 11/18722 0.169316040485474 0.392084042657056 CAV1 1 GO:0033625 positive regulation of integrin activation 1/313 11/18722 0.169316040485474 0.392084042657056 FERMT1 1 GO:0034650 cortisol metabolic process 1/313 11/18722 0.169316040485474 0.392084042657056 CYP11A1 1 GO:0034969 histone arginine methylation 1/313 11/18722 0.169316040485474 0.392084042657056 PRMT1 1 GO:0035246 peptidyl-arginine N-methylation 1/313 11/18722 0.169316040485474 0.392084042657056 PRMT1 1 GO:0035404 histone-serine phosphorylation 1/313 11/18722 0.169316040485474 0.392084042657056 CCNB1 1 GO:0035581 sequestering of extracellular ligand from receptor 1/313 11/18722 0.169316040485474 0.392084042657056 FBN1 1 GO:0036490 regulation of translation in response to endoplasmic reticulum stress 1/313 11/18722 0.169316040485474 0.392084042657056 PPP1R15A 1 GO:0042167 heme catabolic process 1/313 11/18722 0.169316040485474 0.392084042657056 BLVRA 1 GO:0042447 hormone catabolic process 1/313 11/18722 0.169316040485474 0.392084042657056 CYP19A1 1 GO:0043589 skin morphogenesis 1/313 11/18722 0.169316040485474 0.392084042657056 ERRFI1 1 GO:0044068 modulation by symbiont of host cellular process 1/313 11/18722 0.169316040485474 0.392084042657056 SERPINB9 1 GO:0045628 regulation of T-helper 2 cell differentiation 1/313 11/18722 0.169316040485474 0.392084042657056 ANXA1 1 GO:0045654 positive regulation of megakaryocyte differentiation 1/313 11/18722 0.169316040485474 0.392084042657056 SCIN 1 GO:0045657 positive regulation of monocyte differentiation 1/313 11/18722 0.169316040485474 0.392084042657056 JUN 1 GO:0045945 positive regulation of transcription by RNA polymerase III 1/313 11/18722 0.169316040485474 0.392084042657056 ICE1 1 GO:0046149 pigment catabolic process 1/313 11/18722 0.169316040485474 0.392084042657056 BLVRA 1 GO:0046643 regulation of gamma-delta T cell activation 1/313 11/18722 0.169316040485474 0.392084042657056 SOX4 1 GO:0048096 chromatin-mediated maintenance of transcription 1/313 11/18722 0.169316040485474 0.392084042657056 SERTAD1 1 GO:0048103 somatic stem cell division 1/313 11/18722 0.169316040485474 0.392084042657056 LBH 1 GO:0048635 negative regulation of muscle organ development 1/313 11/18722 0.169316040485474 0.392084042657056 YBX3 1 GO:0048715 negative regulation of oligodendrocyte differentiation 1/313 11/18722 0.169316040485474 0.392084042657056 HES1 1 GO:0051081 nuclear membrane disassembly 1/313 11/18722 0.169316040485474 0.392084042657056 NEK6 1 GO:0060159 regulation of dopamine receptor signaling pathway 1/313 11/18722 0.169316040485474 0.392084042657056 CAV2 1 GO:0060174 limb bud formation 1/313 11/18722 0.169316040485474 0.392084042657056 SOX4 1 GO:0060312 regulation of blood vessel remodeling 1/313 11/18722 0.169316040485474 0.392084042657056 TMBIM1 1 GO:0060379 cardiac muscle cell myoblast differentiation 1/313 11/18722 0.169316040485474 0.392084042657056 ISL1 1 GO:0061314 Notch signaling involved in heart development 1/313 11/18722 0.169316040485474 0.392084042657056 GALNT11 1 GO:0070327 thyroid hormone transport 1/313 11/18722 0.169316040485474 0.392084042657056 SLC7A5 1 GO:0071044 histone mRNA catabolic process 1/313 11/18722 0.169316040485474 0.392084042657056 SSB 1 GO:0072110 glomerular mesangial cell proliferation 1/313 11/18722 0.169316040485474 0.392084042657056 EGR1 1 GO:0072173 metanephric tubule morphogenesis 1/313 11/18722 0.169316040485474 0.392084042657056 HES1 1 GO:0072205 metanephric collecting duct development 1/313 11/18722 0.169316040485474 0.392084042657056 AKR1B1 1 GO:0072497 mesenchymal stem cell differentiation 1/313 11/18722 0.169316040485474 0.392084042657056 KRT18 1 GO:0072697 protein localization to cell cortex 1/313 11/18722 0.169316040485474 0.392084042657056 EZR 1 GO:0075522 IRES-dependent viral translational initiation 1/313 11/18722 0.169316040485474 0.392084042657056 SSB 1 GO:0090084 negative regulation of inclusion body assembly 1/313 11/18722 0.169316040485474 0.392084042657056 HSPA1A 1 GO:0090160 Golgi to lysosome transport 1/313 11/18722 0.169316040485474 0.392084042657056 CLN3 1 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1/313 11/18722 0.169316040485474 0.392084042657056 NMT1 1 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation 1/313 11/18722 0.169316040485474 0.392084042657056 HES1 1 GO:1901862 negative regulation of muscle tissue development 1/313 11/18722 0.169316040485474 0.392084042657056 YBX3 1 GO:1902065 response to L-glutamate 1/313 11/18722 0.169316040485474 0.392084042657056 TMBIM6 1 GO:1902188 positive regulation of viral release from host cell 1/313 11/18722 0.169316040485474 0.392084042657056 CAV2 1 GO:1902337 regulation of apoptotic process involved in morphogenesis 1/313 11/18722 0.169316040485474 0.392084042657056 TNFRSF1A 1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway 1/313 11/18722 0.169316040485474 0.392084042657056 HSPA1A 1 GO:1903897 regulation of PERK-mediated unfolded protein response 1/313 11/18722 0.169316040485474 0.392084042657056 PPP1R15A 1 GO:1904181 positive regulation of membrane depolarization 1/313 11/18722 0.169316040485474 0.392084042657056 PARP1 1 GO:1905522 negative regulation of macrophage migration 1/313 11/18722 0.169316040485474 0.392084042657056 MIF 1 GO:1905668 positive regulation of protein localization to endosome 1/313 11/18722 0.169316040485474 0.392084042657056 EZR 1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 1/313 11/18722 0.169316040485474 0.392084042657056 CEBPB 1 GO:0044774 mitotic DNA integrity checkpoint signaling 3/313 85/18722 0.170078477037043 0.392893666310695 SOX4/PPP1R10/PLK2 3 GO:0045069 regulation of viral genome replication 3/313 85/18722 0.170078477037043 0.392893666310695 DDX5/HACD3/TOP2A 3 GO:0055072 iron ion homeostasis 3/313 85/18722 0.170078477037043 0.392893666310695 FTL/FTH1/SRI 3 GO:0060021 roof of mouth development 3/313 85/18722 0.170078477037043 0.392893666310695 ITGB8/TMEM107/TGFBR3 3 GO:0007093 mitotic cell cycle checkpoint signaling 4/313 129/18722 0.17022924122681 0.393003469587912 SOX4/PPP1R10/PLK2/CCNB1 4 GO:0003009 skeletal muscle contraction 2/313 45/18722 0.173313709070405 0.39723376907347 GSTO1/C12orf57 2 GO:0006110 regulation of glycolytic process 2/313 45/18722 0.173313709070405 0.39723376907347 PGAM1/INSR 2 GO:0035272 exocrine system development 2/313 45/18722 0.173313709070405 0.39723376907347 IGF2/WLS 2 GO:0035307 positive regulation of protein dephosphorylation 2/313 45/18722 0.173313709070405 0.39723376907347 CALM1/PPP1R15A 2 GO:0035384 thioester biosynthetic process 2/313 45/18722 0.173313709070405 0.39723376907347 MPC2/TECR 2 GO:0048538 thymus development 2/313 45/18722 0.173313709070405 0.39723376907347 LMO4/HES1 2 GO:0051985 negative regulation of chromosome segregation 2/313 45/18722 0.173313709070405 0.39723376907347 PTTG1/CCNB1 2 GO:0060421 positive regulation of heart growth 2/313 45/18722 0.173313709070405 0.39723376907347 TGFBR3/CCNB1 2 GO:0071616 acyl-CoA biosynthetic process 2/313 45/18722 0.173313709070405 0.39723376907347 MPC2/TECR 2 GO:1901985 positive regulation of protein acetylation 2/313 45/18722 0.173313709070405 0.39723376907347 ISL1/SOX4 2 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process 2/313 45/18722 0.173313709070405 0.39723376907347 HSPA1A/NMT1 2 GO:1905819 negative regulation of chromosome separation 2/313 45/18722 0.173313709070405 0.39723376907347 PTTG1/CCNB1 2 GO:0006493 protein O-linked glycosylation 3/313 86/18722 0.174198065847109 0.398780539194193 GALNT11/VEGFB/B3GNT2 3 GO:0035023 regulation of Rho protein signal transduction 3/313 86/18722 0.174198065847109 0.398780539194193 EPS8L1/ITGB1/STMN1 3 GO:0044772 mitotic cell cycle phase transition 10/313 424/18722 0.174602918516046 0.399467133888574 NEK6/ANXA1/BACH1/SOX4/ITGB1/CALM1/ADAMTS1/PLK2/ID2/CCNB1 10 GO:0098739 import across plasma membrane 5/313 177/18722 0.175617164425514 0.401546273254013 SLC7A5/ITGB1/SLC43A2/SLC2A1/RGS2 5 GO:0050670 regulation of lymphocyte proliferation 6/313 225/18722 0.176162773108801 0.402552027145982 IGF2/EFNB1/ANXA1/MIF/CEBPB/HES1 6 GO:0018108 peptidyl-tyrosine phosphorylation 9/313 375/18722 0.17814656834285 0.403171924290049 IGF2/CAV1/MIF/TNFRSF1A/ISL1/INSR/FLT1/ERRFI1/HES1 9 GO:0019646 aerobic electron transport chain 3/313 87/18722 0.178345581325254 0.403171924290049 UQCRB/COX4I1/NDUFB1 3 GO:0019915 lipid storage 3/313 87/18722 0.178345581325254 0.403171924290049 CAV1/PLIN2/MEST 3 GO:2000177 regulation of neural precursor cell proliferation 3/313 87/18722 0.178345581325254 0.403171924290049 RHOA/BTG2/ID2 3 GO:0048015 phosphatidylinositol-mediated signaling 5/313 178/18722 0.178413923424307 0.403171924290049 FN1/EZR/INSR/FLT1/EXOC1 5 GO:0031294 lymphocyte costimulation 2/313 46/18722 0.179307897087251 0.403171924290049 CAV1/EFNB1 2 GO:0033047 regulation of mitotic sister chromatid segregation 2/313 46/18722 0.179307897087251 0.403171924290049 PTTG1/CCNB1 2 GO:0043462 regulation of ATPase activity 2/313 46/18722 0.179307897087251 0.403171924290049 PFN1/TPM1 2 GO:0045851 pH reduction 2/313 46/18722 0.179307897087251 0.403171924290049 CLIC4/CLN3 2 GO:0061028 establishment of endothelial barrier 2/313 46/18722 0.179307897087251 0.403171924290049 TNFRSF1A/EZR 2 GO:0070828 heterochromatin organization 2/313 46/18722 0.179307897087251 0.403171924290049 MBD3/DNMT3A 2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 2/313 46/18722 0.179307897087251 0.403171924290049 ANXA1/ADAMTS1 2 GO:0032103 positive regulation of response to external stimulus 10/313 427/18722 0.179884742227804 0.403171924290049 NEAT1/TNFRSF1A/SERPINE1/VEGFB/PGF/CTSC/CEBPB/TMSB4X/HSPB1/LGMN 10 GO:0072175 epithelial tube formation 4/313 132/18722 0.180092031171117 0.403171924290049 LMO4/PFN1/SOX4/BRD2 4 GO:0032944 regulation of mononuclear cell proliferation 6/313 227/18722 0.181100176600026 0.403171924290049 IGF2/EFNB1/ANXA1/MIF/CEBPB/HES1 6 GO:0071826 ribonucleoprotein complex subunit organization 6/313 227/18722 0.181100176600026 0.403171924290049 RPS27/RPL38/RPS28/EIF4H/EIF4B/SCAF11 6 GO:0001843 neural tube closure 3/313 88/18722 0.18252006655319 0.403171924290049 LMO4/PFN1/BRD2 3 GO:0031110 regulation of microtubule polymerization or depolymerization 3/313 88/18722 0.18252006655319 0.403171924290049 STMN3/HSPA1A/STMN1 3 GO:0000012 single strand break repair 1/313 12/18722 0.183211827954238 0.403171924290049 PARP1 1 GO:0003207 cardiac chamber formation 1/313 12/18722 0.183211827954238 0.403171924290049 SOX4 1 GO:0006563 L-serine metabolic process 1/313 12/18722 0.183211827954238 0.403171924290049 SERINC5 1 GO:0006787 porphyrin-containing compound catabolic process 1/313 12/18722 0.183211827954238 0.403171924290049 BLVRA 1 GO:0009886 post-embryonic animal morphogenesis 1/313 12/18722 0.183211827954238 0.403171924290049 FBN1 1 GO:0010454 negative regulation of cell fate commitment 1/313 12/18722 0.183211827954238 0.403171924290049 HES1 1 GO:0010459 negative regulation of heart rate 1/313 12/18722 0.183211827954238 0.403171924290049 SRI 1 GO:0010587 miRNA catabolic process 1/313 12/18722 0.183211827954238 0.403171924290049 KCNQ1OT1 1 GO:0021527 spinal cord association neuron differentiation 1/313 12/18722 0.183211827954238 0.403171924290049 LMO4 1 GO:0021559 trigeminal nerve development 1/313 12/18722 0.183211827954238 0.403171924290049 ISL1 1 GO:0021978 telencephalon regionalization 1/313 12/18722 0.183211827954238 0.403171924290049 TRA2B 1 GO:0030238 male sex determination 1/313 12/18722 0.183211827954238 0.403171924290049 MAP3K4 1 GO:0030397 membrane disassembly 1/313 12/18722 0.183211827954238 0.403171924290049 NEK6 1 GO:0032536 regulation of cell projection size 1/313 12/18722 0.183211827954238 0.403171924290049 EZR 1 GO:0033015 tetrapyrrole catabolic process 1/313 12/18722 0.183211827954238 0.403171924290049 BLVRA 1 GO:0033127 regulation of histone phosphorylation 1/313 12/18722 0.183211827954238 0.403171924290049 CCNB1 1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 1/313 12/18722 0.183211827954238 0.403171924290049 CROT 1 GO:0043471 regulation of cellular carbohydrate catabolic process 1/313 12/18722 0.183211827954238 0.403171924290049 PGAM1 1 GO:0043476 pigment accumulation 1/313 12/18722 0.183211827954238 0.403171924290049 CD63 1 GO:0043482 cellular pigment accumulation 1/313 12/18722 0.183211827954238 0.403171924290049 CD63 1 GO:0045605 negative regulation of epidermal cell differentiation 1/313 12/18722 0.183211827954238 0.403171924290049 HES1 1 GO:0045683 negative regulation of epidermis development 1/313 12/18722 0.183211827954238 0.403171924290049 HES1 1 GO:0048934 peripheral nervous system neuron differentiation 1/313 12/18722 0.183211827954238 0.403171924290049 ISL1 1 GO:0048935 peripheral nervous system neuron development 1/313 12/18722 0.183211827954238 0.403171924290049 ISL1 1 GO:0051001 negative regulation of nitric-oxide synthase activity 1/313 12/18722 0.183211827954238 0.403171924290049 CAV1 1 GO:0051340 regulation of ligase activity 1/313 12/18722 0.183211827954238 0.403171924290049 TMSB4X 1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development 1/313 12/18722 0.183211827954238 0.403171924290049 RGS2 1 GO:0061307 cardiac neural crest cell differentiation involved in heart development 1/313 12/18722 0.183211827954238 0.403171924290049 HES1 1 GO:0061308 cardiac neural crest cell development involved in heart development 1/313 12/18722 0.183211827954238 0.403171924290049 HES1 1 GO:0061517 macrophage proliferation 1/313 12/18722 0.183211827954238 0.403171924290049 CLU 1 GO:0061620 glycolytic process through glucose-6-phosphate 1/313 12/18722 0.183211827954238 0.403171924290049 ENO1 1 GO:0070213 protein auto-ADP-ribosylation 1/313 12/18722 0.183211827954238 0.403171924290049 PARP1 1 GO:0071107 response to parathyroid hormone 1/313 12/18722 0.183211827954238 0.403171924290049 GJA1 1 GO:0071635 negative regulation of transforming growth factor beta production 1/313 12/18722 0.183211827954238 0.403171924290049 FN1 1 GO:0071872 cellular response to epinephrine stimulus 1/313 12/18722 0.183211827954238 0.403171924290049 PDE4B 1 GO:0072683 T cell extravasation 1/313 12/18722 0.183211827954238 0.403171924290049 CD99 1 GO:0090385 phagosome-lysosome fusion 1/313 12/18722 0.183211827954238 0.403171924290049 CLN3 1 GO:1901894 regulation of ATPase-coupled calcium transmembrane transporter activity 1/313 12/18722 0.183211827954238 0.403171924290049 C4orf3 1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA 1/313 12/18722 0.183211827954238 0.403171924290049 DDX5 1 GO:1904667 negative regulation of ubiquitin protein ligase activity 1/313 12/18722 0.183211827954238 0.403171924290049 RPL23 1 GO:1904748 regulation of apoptotic process involved in development 1/313 12/18722 0.183211827954238 0.403171924290049 TNFRSF1A 1 GO:1905666 regulation of protein localization to endosome 1/313 12/18722 0.183211827954238 0.403171924290049 EZR 1 GO:2000035 regulation of stem cell division 1/313 12/18722 0.183211827954238 0.403171924290049 LBH 1 GO:2000303 regulation of ceramide biosynthetic process 1/313 12/18722 0.183211827954238 0.403171924290049 ORMDL1 1 GO:2000628 regulation of miRNA metabolic process 1/313 12/18722 0.183211827954238 0.403171924290049 KCNQ1OT1 1 GO:2001204 regulation of osteoclast development 1/313 12/18722 0.183211827954238 0.403171924290049 FBN1 1 GO:0010565 regulation of cellular ketone metabolic process 4/313 133/18722 0.183421582473415 0.403400326098378 CAV1/ANXA1/CLN3/EGR1 4 GO:0018212 peptidyl-tyrosine modification 9/313 378/18722 0.183845625291973 0.404099477763591 IGF2/CAV1/MIF/TNFRSF1A/ISL1/INSR/FLT1/ERRFI1/HES1 9 GO:0001774 microglial cell activation 2/313 47/18722 0.185333253569428 0.404334496469234 CTSC/CLU 2 GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 2/313 47/18722 0.185333253569428 0.404334496469234 RHOA/TPM1 2 GO:0010712 regulation of collagen metabolic process 2/313 47/18722 0.185333253569428 0.404334496469234 ITGB1/ERRFI1 2 GO:0010761 fibroblast migration 2/313 47/18722 0.185333253569428 0.404334496469234 ITGB1/CLN3 2 GO:0014911 positive regulation of smooth muscle cell migration 2/313 47/18722 0.185333253569428 0.404334496469234 SEMA6D/ADAMTS1 2 GO:0035315 hair cell differentiation 2/313 47/18722 0.185333253569428 0.404334496469234 MCOLN3/HES1 2 GO:0045646 regulation of erythrocyte differentiation 2/313 47/18722 0.185333253569428 0.404334496469234 PRMT1/HSPA1A 2 GO:0045747 positive regulation of Notch signaling pathway 2/313 47/18722 0.185333253569428 0.404334496469234 AAK1/HES1 2 GO:0045911 positive regulation of DNA recombination 2/313 47/18722 0.185333253569428 0.404334496469234 FUS/PARP1 2 GO:0048512 circadian behavior 2/313 47/18722 0.185333253569428 0.404334496469234 EGR1/ID2 2 GO:0051489 regulation of filopodium assembly 2/313 47/18722 0.185333253569428 0.404334496469234 RAB17/CLN3 2 GO:0101023 vascular endothelial cell proliferation 2/313 47/18722 0.185333253569428 0.404334496469234 IGF2/FLT1 2 GO:1905562 regulation of vascular endothelial cell proliferation 2/313 47/18722 0.185333253569428 0.404334496469234 IGF2/FLT1 2 GO:0001649 osteoblast differentiation 6/313 229/18722 0.18609253409158 0.40575846350896 IGF2/DDX5/CLIC1/CEBPB/TPM4/FHL2 6 GO:0060606 tube closure 3/313 89/18722 0.186720569961482 0.406595820970491 LMO4/PFN1/BRD2 3 GO:0032640 tumor necrosis factor production 5/313 181/18722 0.186903779011915 0.406595820970491 MIF/ISL1/HSPB1/ERRFI1/CLU 5 GO:0032680 regulation of tumor necrosis factor production 5/313 181/18722 0.186903779011915 0.406595820970491 MIF/ISL1/HSPB1/ERRFI1/CLU 5 GO:0097696 receptor signaling pathway via STAT 5/313 181/18722 0.186903779011915 0.406595820970491 CAV1/TNFRSF1A/ISL1/AKR1B1/HES1 5 GO:0050863 regulation of T cell activation 8/313 329/18722 0.187312515776989 0.406794286628025 IGF2/CAV1/EFNB1/ANXA1/SOX4/RHOA/CEBPB/HES1 8 GO:0045333 cellular respiration 6/313 230/18722 0.18860888646908 0.406794286628025 IDH1/UQCRB/COX4I1/RHOA/NDUFB1/CCNB1 6 GO:0048880 sensory system development 9/313 381/18722 0.189625264490855 0.406794286628025 RDH13/FBN1/ATP2B1/ISL1/CLIC4/C12orf57/FKBP8/FLT1/MFAP5 9 GO:0048017 inositol lipid-mediated signaling 5/313 182/18722 0.189766033284212 0.406794286628025 FN1/EZR/INSR/FLT1/EXOC1 5 GO:0032392 DNA geometric change 3/313 90/18722 0.190946145726863 0.406794286628025 HMGB3/ANXA1/TOP2A 3 GO:0010569 regulation of double-strand break repair via homologous recombination 2/313 48/18722 0.1913870727681 0.406794286628025 FUS/PARP1 2 GO:0030261 chromosome condensation 2/313 48/18722 0.1913870727681 0.406794286628025 TOP2A/CCNB1 2 GO:0042149 cellular response to glucose starvation 2/313 48/18722 0.1913870727681 0.406794286628025 PMAIP1/SLC2A1 2 GO:0042391 regulation of membrane potential 10/313 434/18722 0.192491996429464 0.406794286628025 CAV1/PMAIP1/DSP/JUN/SRI/CLIC1/PARP1/CALM1/CLN3/GJA1 10 GO:0006644 phospholipid metabolic process 9/313 383/18722 0.19352218864823 0.406794286628025 IDH1/ABHD8/GPX4/DBI/SERINC5/ISYNA1/CLN3/PRDX6/PGP 9 GO:0098876 vesicle-mediated transport to the plasma membrane 4/313 136/18722 0.193529666955745 0.406794286628025 KRT18/RAB17/CLN3/EXOC1 4 GO:0042110 T cell activation 11/313 487/18722 0.19425773447172 0.406794286628025 IGF2/CAV1/EFNB1/ANXA1/SOX4/MYH9/CD151/RHOA/CEBPB/EGR1/HES1 11 GO:0045582 positive regulation of T cell differentiation 3/313 91/18722 0.195195854149809 0.406794286628025 ANXA1/SOX4/RHOA 3 GO:0051952 regulation of amine transport 3/313 91/18722 0.195195854149809 0.406794286628025 ITGB1/SLC43A2/RGS2 3 GO:0051983 regulation of chromosome segregation 3/313 91/18722 0.195195854149809 0.406794286628025 NEK6/PTTG1/CCNB1 3 GO:0048285 organelle fission 11/313 488/18722 0.195993514506448 0.406794286628025 IGF2/NEK6/CCSAP/CAV2/INSR/RHOA/PTTG1/HSPA1A/CDC20/TOP2A/CCNB1 11 GO:0001682 tRNA 5'-leader removal 1/313 13/18722 0.196875895183011 0.406794286628025 SSB 1 GO:0001768 establishment of T cell polarity 1/313 13/18722 0.196875895183011 0.406794286628025 MYH9 1 GO:0001778 plasma membrane repair 1/313 13/18722 0.196875895183011 0.406794286628025 MYH9 1 GO:0001886 endothelial cell morphogenesis 1/313 13/18722 0.196875895183011 0.406794286628025 CLIC4 1 GO:0002638 negative regulation of immunoglobulin production 1/313 13/18722 0.196875895183011 0.406794286628025 TMBIM6 1 GO:0003334 keratinocyte development 1/313 13/18722 0.196875895183011 0.406794286628025 FLNB 1 GO:0005513 detection of calcium ion 1/313 13/18722 0.196875895183011 0.406794286628025 CALM1 1 GO:0007183 SMAD protein complex assembly 1/313 13/18722 0.196875895183011 0.406794286628025 PARP1 1 GO:0009437 carnitine metabolic process 1/313 13/18722 0.196875895183011 0.406794286628025 CROT 1 GO:0009650 UV protection 1/313 13/18722 0.196875895183011 0.406794286628025 GPX1 1 GO:0010917 negative regulation of mitochondrial membrane potential 1/313 13/18722 0.196875895183011 0.406794286628025 PMAIP1 1 GO:0014029 neural crest formation 1/313 13/18722 0.196875895183011 0.406794286628025 PDCD6 1 GO:0014745 negative regulation of muscle adaptation 1/313 13/18722 0.196875895183011 0.406794286628025 ERRFI1 1 GO:0015801 aromatic amino acid transport 1/313 13/18722 0.196875895183011 0.406794286628025 SLC7A5 1 GO:0015809 arginine transport 1/313 13/18722 0.196875895183011 0.406794286628025 CLN3 1 GO:0015816 glycine transport 1/313 13/18722 0.196875895183011 0.406794286628025 RGS2 1 GO:0016056 rhodopsin mediated signaling pathway 1/313 13/18722 0.196875895183011 0.406794286628025 NMT1 1 GO:0021514 ventral spinal cord interneuron differentiation 1/313 13/18722 0.196875895183011 0.406794286628025 LMO4 1 GO:0021984 adenohypophysis development 1/313 13/18722 0.196875895183011 0.406794286628025 HES1 1 GO:0031392 regulation of prostaglandin biosynthetic process 1/313 13/18722 0.196875895183011 0.406794286628025 ANXA1 1 GO:0032042 mitochondrial DNA metabolic process 1/313 13/18722 0.196875895183011 0.406794286628025 PARP1 1 GO:0032352 positive regulation of hormone metabolic process 1/313 13/18722 0.196875895183011 0.406794286628025 EGR1 1 GO:0032429 regulation of phospholipase A2 activity 1/313 13/18722 0.196875895183011 0.406794286628025 ANXA1 1 GO:0032530 regulation of microvillus organization 1/313 13/18722 0.196875895183011 0.406794286628025 EZR 1 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway 1/313 13/18722 0.196875895183011 0.406794286628025 PARP1 1 GO:0036462 TRAIL-activated apoptotic signaling pathway 1/313 13/18722 0.196875895183011 0.406794286628025 TIMP3 1 GO:0042308 negative regulation of protein import into nucleus 1/313 13/18722 0.196875895183011 0.406794286628025 FERMT1 1 GO:0042492 gamma-delta T cell differentiation 1/313 13/18722 0.196875895183011 0.406794286628025 SOX4 1 GO:0042541 hemoglobin biosynthetic process 1/313 13/18722 0.196875895183011 0.406794286628025 PRMT1 1 GO:0042659 regulation of cell fate specification 1/313 13/18722 0.196875895183011 0.406794286628025 LMO4 1 GO:0046415 urate metabolic process 1/313 13/18722 0.196875895183011 0.406794286628025 SLC22A11 1 GO:0046689 response to mercury ion 1/313 13/18722 0.196875895183011 0.406794286628025 BSG 1 GO:0048012 hepatocyte growth factor receptor signaling pathway 1/313 13/18722 0.196875895183011 0.406794286628025 STMN1 1 GO:0048207 vesicle targeting, rough ER to cis-Golgi 1/313 13/18722 0.196875895183011 0.406794286628025 PDCD6 1 GO:0048208 COPII vesicle coating 1/313 13/18722 0.196875895183011 0.406794286628025 PDCD6 1 GO:0048820 hair follicle maturation 1/313 13/18722 0.196875895183011 0.406794286628025 FERMT1 1 GO:0051451 myoblast migration 1/313 13/18722 0.196875895183011 0.406794286628025 ANXA1 1 GO:0051481 negative regulation of cytosolic calcium ion concentration 1/313 13/18722 0.196875895183011 0.406794286628025 ATP2B1 1 GO:0051709 regulation of killing of cells of other organism 1/313 13/18722 0.196875895183011 0.406794286628025 SERPINB9 1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore 1/313 13/18722 0.196875895183011 0.406794286628025 CCNB1 1 GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1/313 13/18722 0.196875895183011 0.406794286628025 BTG2 1 GO:0061000 negative regulation of dendritic spine development 1/313 13/18722 0.196875895183011 0.406794286628025 PLK2 1 GO:0061469 regulation of type B pancreatic cell proliferation 1/313 13/18722 0.196875895183011 0.406794286628025 ERRFI1 1 GO:0061615 glycolytic process through fructose-6-phosphate 1/313 13/18722 0.196875895183011 0.406794286628025 ENO1 1 GO:0061744 motor behavior 1/313 13/18722 0.196875895183011 0.406794286628025 C12orf57 1 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway 1/313 13/18722 0.196875895183011 0.406794286628025 HSPA1A 1 GO:0071801 regulation of podosome assembly 1/313 13/18722 0.196875895183011 0.406794286628025 RHOA 1 GO:0072672 neutrophil extravasation 1/313 13/18722 0.196875895183011 0.406794286628025 CD99 1 GO:0090153 regulation of sphingolipid biosynthetic process 1/313 13/18722 0.196875895183011 0.406794286628025 ORMDL1 1 GO:0098814 spontaneous synaptic transmission 1/313 13/18722 0.196875895183011 0.406794286628025 ITGB1 1 GO:0098840 protein transport along microtubule 1/313 13/18722 0.196875895183011 0.406794286628025 HSPB1 1 GO:0099118 microtubule-based protein transport 1/313 13/18722 0.196875895183011 0.406794286628025 HSPB1 1 GO:0110096 cellular response to aldehyde 1/313 13/18722 0.196875895183011 0.406794286628025 AKR1B1 1 GO:1900115 extracellular regulation of signal transduction 1/313 13/18722 0.196875895183011 0.406794286628025 FBN1 1 GO:1900116 extracellular negative regulation of signal transduction 1/313 13/18722 0.196875895183011 0.406794286628025 FBN1 1 GO:1901096 regulation of autophagosome maturation 1/313 13/18722 0.196875895183011 0.406794286628025 CLN3 1 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance 1/313 13/18722 0.196875895183011 0.406794286628025 NRP2 1 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding 1/313 13/18722 0.196875895183011 0.406794286628025 TMSB4X 1 GO:1903054 negative regulation of extracellular matrix organization 1/313 13/18722 0.196875895183011 0.406794286628025 TNFRSF1A 1 GO:1903651 positive regulation of cytoplasmic transport 1/313 13/18722 0.196875895183011 0.406794286628025 EZR 1 GO:1904590 negative regulation of protein import 1/313 13/18722 0.196875895183011 0.406794286628025 FERMT1 1 GO:1905038 regulation of membrane lipid metabolic process 1/313 13/18722 0.196875895183011 0.406794286628025 ORMDL1 1 GO:1905907 negative regulation of amyloid fibril formation 1/313 13/18722 0.196875895183011 0.406794286628025 CLU 1 GO:1990403 embryonic brain development 1/313 13/18722 0.196875895183011 0.406794286628025 TRA2B 1 GO:2001023 regulation of response to drug 1/313 13/18722 0.196875895183011 0.406794286628025 ADIRF 1 GO:2001198 regulation of dendritic cell differentiation 1/313 13/18722 0.196875895183011 0.406794286628025 CEBPB 1 GO:0050684 regulation of mRNA processing 4/313 137/18722 0.196937300565848 0.406794286628025 DDX5/PRDX6/TRA2B/CCNB1 4 GO:0045786 negative regulation of cell cycle 9/313 385/18722 0.197453504776969 0.406794286628025 TIMP2/BTG3/SOX4/PTTG1/PPP1R10/BTG2/RHOB/PLK2/CCNB1 9 GO:0006953 acute-phase response 2/313 49/18722 0.197466730151981 0.406794286628025 FN1/CEBPB 2 GO:0007622 rhythmic behavior 2/313 49/18722 0.197466730151981 0.406794286628025 EGR1/ID2 2 GO:0009395 phospholipid catabolic process 2/313 49/18722 0.197466730151981 0.406794286628025 IDH1/PRDX6 2 GO:0009994 oocyte differentiation 2/313 49/18722 0.197466730151981 0.406794286628025 LGR5/CCNB1 2 GO:0014075 response to amine 2/313 49/18722 0.197466730151981 0.406794286628025 CALM1/RGS2 2 GO:0030225 macrophage differentiation 2/313 49/18722 0.197466730151981 0.406794286628025 PARP1/ID2 2 GO:0030857 negative regulation of epithelial cell differentiation 2/313 49/18722 0.197466730151981 0.406794286628025 CAV1/HES1 2 GO:0032692 negative regulation of interleukin-1 production 2/313 49/18722 0.197466730151981 0.406794286628025 SERPINB1/ERRFI1 2 GO:0035088 establishment or maintenance of apical/basal cell polarity 2/313 49/18722 0.197466730151981 0.406794286628025 CLIC4/RHOA 2 GO:0050832 defense response to fungus 2/313 49/18722 0.197466730151981 0.406794286628025 GAPDH/COTL1 2 GO:0052372 modulation by symbiont of entry into host 2/313 49/18722 0.197466730151981 0.406794286628025 CAV1/LY6E 2 GO:0061245 establishment or maintenance of bipolar cell polarity 2/313 49/18722 0.197466730151981 0.406794286628025 CLIC4/RHOA 2 GO:0070169 positive regulation of biomineral tissue development 2/313 49/18722 0.197466730151981 0.406794286628025 ATP2B1/CEBPB 2 GO:1904894 positive regulation of receptor signaling pathway via STAT 2/313 49/18722 0.197466730151981 0.406794286628025 AKR1B1/HES1 2 GO:0043433 negative regulation of DNA-binding transcription factor activity 5/313 185/18722 0.198445919124296 0.408369521138485 ANXA4/SRI/TMSB4X/ID2/HES1 5 GO:0051896 regulation of protein kinase B signaling 5/313 185/18722 0.198445919124296 0.408369521138485 IGF2/GPX1/PDCD6/INSR/ITGB1 5 GO:0022409 positive regulation of cell-cell adhesion 7/313 284/18722 0.199159582848519 0.409616710915349 IGF2/CAV1/EFNB1/ANXA1/SOX4/RHOA/HES1 7 GO:0032465 regulation of cytokinesis 3/313 92/18722 0.199468762013005 0.410031089083969 RHOA/CALM1/PLK2 3 GO:0008217 regulation of blood pressure 5/313 186/18722 0.201369344975211 0.412601235909918 ATP2B1/RHOA/TPM1/GJA1/ID2 5 GO:0071478 cellular response to radiation 5/313 186/18722 0.201369344975211 0.412601235909918 ADIRF/PARP1/NMT1/EGR1/RHOB 5 GO:0071706 tumor necrosis factor superfamily cytokine production 5/313 186/18722 0.201369344975211 0.412601235909918 MIF/ISL1/HSPB1/ERRFI1/CLU 5 GO:0120032 regulation of plasma membrane bounded cell projection assembly 5/313 186/18722 0.201369344975211 0.412601235909918 CAV1/EPS8L1/RAB17/PFN1/CLN3 5 GO:1902115 regulation of organelle assembly 5/313 186/18722 0.201369344975211 0.412601235909918 CCSAP/EZR/RHOA/HSPA1A/PLK2 5 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 5/313 186/18722 0.201369344975211 0.412601235909918 MIF/ISL1/HSPB1/ERRFI1/CLU 5 GO:1903037 regulation of leukocyte cell-cell adhesion 8/313 336/18722 0.202108498945176 0.413892983046952 IGF2/CAV1/EFNB1/ANXA1/SOX4/RHOA/CEBPB/HES1 8 GO:0007632 visual behavior 2/313 50/18722 0.203569680462655 0.414694824059139 ITGB1/DYNLRB1 2 GO:0030490 maturation of SSU-rRNA 2/313 50/18722 0.203569680462655 0.414694824059139 RPS21/RPS28 2 GO:0042572 retinol metabolic process 2/313 50/18722 0.203569680462655 0.414694824059139 RDH13/AKR1B1 2 GO:0043628 ncRNA 3'-end processing 2/313 50/18722 0.203569680462655 0.414694824059139 RPS21/SSB 2 GO:0045814 negative regulation of gene expression, epigenetic 2/313 50/18722 0.203569680462655 0.414694824059139 MBD3/DNMT3A 2 GO:0046638 positive regulation of alpha-beta T cell differentiation 2/313 50/18722 0.203569680462655 0.414694824059139 ANXA1/RHOA 2 GO:0110151 positive regulation of biomineralization 2/313 50/18722 0.203569680462655 0.414694824059139 ATP2B1/CEBPB 2 GO:0033273 response to vitamin 3/313 93/18722 0.203763942921304 0.414694824059139 STC2/ATP2B1/DNMT3A 3 GO:0060993 kidney morphogenesis 3/313 93/18722 0.203763942921304 0.414694824059139 SOX4/MAGED1/HES1 3 GO:0106027 neuron projection organization 3/313 93/18722 0.203763942921304 0.414694824059139 CFL1/INSR/LGMN 3 GO:1901992 positive regulation of mitotic cell cycle phase transition 3/313 93/18722 0.203763942921304 0.414694824059139 ANXA1/ADAMTS1/CCNB1 3 GO:0045598 regulation of fat cell differentiation 4/313 139/18722 0.203807201422288 0.414694824059139 ADIRF/CEBPB/ID2/HES1 4 GO:0033673 negative regulation of kinase activity 6/313 237/18722 0.206583333717065 0.415494624852157 CAV1/MLLT1/GADD45B/HSPB1/ERRFI1/RGS2 6 GO:0030308 negative regulation of cell growth 5/313 188/18722 0.207259740794293 0.415494624852157 ENO1/SEMA6D/HSPA1A/GJA1/RGS2 5 GO:0060491 regulation of cell projection assembly 5/313 188/18722 0.207259740794293 0.415494624852157 CAV1/EPS8L1/RAB17/PFN1/CLN3 5 GO:0030177 positive regulation of Wnt signaling pathway 4/313 140/18722 0.207268542832709 0.415494624852157 CAV1/WLS/SOX4/LGR5 4 GO:0046165 alcohol biosynthetic process 4/313 140/18722 0.207268542832709 0.415494624852157 DHCR24/AKR1B1/ISYNA1/PGP 4 GO:0001738 morphogenesis of a polarized epithelium 3/313 94/18722 0.208080477623785 0.415494624852157 ACTG1/RHOA/ACTB 3 GO:0014020 primary neural tube formation 3/313 94/18722 0.208080477623785 0.415494624852157 LMO4/PFN1/BRD2 3 GO:0030316 osteoclast differentiation 3/313 94/18722 0.208080477623785 0.415494624852157 FBN1/FOS/CEBPB 3 GO:0032091 negative regulation of protein binding 3/313 94/18722 0.208080477623785 0.415494624852157 CAV1/TMBIM6/ACTB 3 GO:0061326 renal tubule development 3/313 94/18722 0.208080477623785 0.415494624852157 MAGED1/LGR5/HES1 3 GO:1990830 cellular response to leukemia inhibitory factor 3/313 94/18722 0.208080477623785 0.415494624852157 NRP2/TLE4/B3GNT2 3 GO:0046651 lymphocyte proliferation 7/313 288/18722 0.208547969178818 0.415494624852157 IGF2/EFNB1/ANXA1/MIF/CD151/CEBPB/HES1 7 GO:0006636 unsaturated fatty acid biosynthetic process 2/313 51/18722 0.209693455811878 0.415494624852157 ANXA1/MIF 2 GO:0051339 regulation of lyase activity 2/313 51/18722 0.209693455811878 0.415494624852157 TIMP2/PHPT1 2 GO:0046578 regulation of Ras protein signal transduction 5/313 189/18722 0.210226156363462 0.415494624852157 EPS8L1/STMN3/TIMP2/ITGB1/STMN1 5 GO:0000212 meiotic spindle organization 1/313 14/18722 0.210312094060968 0.415494624852157 MYH9 1 GO:0001767 establishment of lymphocyte polarity 1/313 14/18722 0.210312094060968 0.415494624852157 MYH9 1 GO:0002829 negative regulation of type 2 immune response 1/313 14/18722 0.210312094060968 0.415494624852157 ANXA1 1 GO:0003376 sphingosine-1-phosphate receptor signaling pathway 1/313 14/18722 0.210312094060968 0.415494624852157 EZR 1 GO:0006521 regulation of cellular amino acid metabolic process 1/313 14/18722 0.210312094060968 0.415494624852157 CLN3 1 GO:0006596 polyamine biosynthetic process 1/313 14/18722 0.210312094060968 0.415494624852157 OAZ1 1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity 1/313 14/18722 0.210312094060968 0.415494624852157 ERRFI1 1 GO:0009214 cyclic nucleotide catabolic process 1/313 14/18722 0.210312094060968 0.415494624852157 PDE4B 1 GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1/313 14/18722 0.210312094060968 0.415494624852157 FBLN1 1 GO:0018158 protein oxidation 1/313 14/18722 0.210312094060968 0.415494624852157 GPX1 1 GO:0022038 corpus callosum development 1/313 14/18722 0.210312094060968 0.415494624852157 C12orf57 1 GO:0030049 muscle filament sliding 1/313 14/18722 0.210312094060968 0.415494624852157 TPM1 1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway 1/313 14/18722 0.210312094060968 0.415494624852157 PDCD6 1 GO:0031115 negative regulation of microtubule polymerization 1/313 14/18722 0.210312094060968 0.415494624852157 STMN1 1 GO:0031650 regulation of heat generation 1/313 14/18722 0.210312094060968 0.415494624852157 ARRDC3 1 GO:0032966 negative regulation of collagen biosynthetic process 1/313 14/18722 0.210312094060968 0.415494624852157 ERRFI1 1 GO:0035437 maintenance of protein localization in endoplasmic reticulum 1/313 14/18722 0.210312094060968 0.415494624852157 GJA1 1 GO:0036151 phosphatidylcholine acyl-chain remodeling 1/313 14/18722 0.210312094060968 0.415494624852157 DBI 1 GO:0036295 cellular response to increased oxygen levels 1/313 14/18722 0.210312094060968 0.415494624852157 CAV1 1 GO:0038166 angiotensin-activated signaling pathway 1/313 14/18722 0.210312094060968 0.415494624852157 CAV1 1 GO:0042921 glucocorticoid receptor signaling pathway 1/313 14/18722 0.210312094060968 0.415494624852157 NR3C1 1 GO:0043558 regulation of translational initiation in response to stress 1/313 14/18722 0.210312094060968 0.415494624852157 PPP1R15A 1 GO:0043922 negative regulation by host of viral transcription 1/313 14/18722 0.210312094060968 0.415494624852157 JUN 1 GO:0043951 negative regulation of cAMP-mediated signaling 1/313 14/18722 0.210312094060968 0.415494624852157 RGS2 1 GO:0045837 negative regulation of membrane potential 1/313 14/18722 0.210312094060968 0.415494624852157 PMAIP1 1 GO:0046348 amino sugar catabolic process 1/313 14/18722 0.210312094060968 0.415494624852157 NPL 1 GO:0048172 regulation of short-term neuronal synaptic plasticity 1/313 14/18722 0.210312094060968 0.415494624852157 CLN3 1 GO:0051917 regulation of fibrinolysis 1/313 14/18722 0.210312094060968 0.415494624852157 SERPINE1 1 GO:0051984 positive regulation of chromosome segregation 1/313 14/18722 0.210312094060968 0.415494624852157 CCNB1 1 GO:0060911 cardiac cell fate commitment 1/313 14/18722 0.210312094060968 0.415494624852157 ISL1 1 GO:0061043 regulation of vascular wound healing 1/313 14/18722 0.210312094060968 0.415494624852157 SERPINE1 1 GO:0061709 reticulophagy 1/313 14/18722 0.210312094060968 0.415494624852157 UBA5 1 GO:0070278 extracellular matrix constituent secretion 1/313 14/18722 0.210312094060968 0.415494624852157 TNFRSF1A 1 GO:0071236 cellular response to antibiotic 1/313 14/18722 0.210312094060968 0.415494624852157 RPL23 1 GO:0072350 tricarboxylic acid metabolic process 1/313 14/18722 0.210312094060968 0.415494624852157 IDH1 1 GO:0090128 regulation of synapse maturation 1/313 14/18722 0.210312094060968 0.415494624852157 CDC20 1 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading 1/313 14/18722 0.210312094060968 0.415494624852157 FBLN1 1 GO:1901722 regulation of cell proliferation involved in kidney development 1/313 14/18722 0.210312094060968 0.415494624852157 EGR1 1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/313 14/18722 0.210312094060968 0.415494624852157 MIF 1 GO:2001140 positive regulation of phospholipid transport 1/313 14/18722 0.210312094060968 0.415494624852157 DBI 1 GO:2001256 regulation of store-operated calcium entry 1/313 14/18722 0.210312094060968 0.415494624852157 SARAF 1 GO:0016055 Wnt signaling pathway 10/313 444/18722 0.211157461147465 0.416948368562449 CAV1/WLS/TLE4/ISL1/SOX4/RHOA/LGR5/CTNND1/EGR1/FERMT1 10 GO:0008593 regulation of Notch signaling pathway 3/313 95/18722 0.212417454318478 0.418567934053027 GALNT11/AAK1/HES1 3 GO:0045666 positive regulation of neuron differentiation 3/313 95/18722 0.212417454318478 0.418567934053027 TIMP2/RHOA/HMG20B 3 GO:1901379 regulation of potassium ion transmembrane transport 3/313 95/18722 0.212417454318478 0.418567934053027 CAV1/CD63/ITGB1 3 GO:1990823 response to leukemia inhibitory factor 3/313 95/18722 0.212417454318478 0.418567934053027 NRP2/TLE4/B3GNT2 3 GO:0097553 calcium ion transmembrane import into cytosol 4/313 142/18722 0.214241693250461 0.421944193587431 GSTO1/SRI/CALM1/MCOLN3 4 GO:0032886 regulation of microtubule-based process 6/313 240/18722 0.21446951623207 0.422174482055579 STMN3/CCSAP/RHOA/HSPA1A/STMN1/PLK2 6 GO:0198738 cell-cell signaling by wnt 10/313 446/18722 0.214978474514469 0.422957649858699 CAV1/WLS/TLE4/ISL1/SOX4/RHOA/LGR5/CTNND1/EGR1/FERMT1 10 GO:0032943 mononuclear cell proliferation 7/313 291/18722 0.215696980073993 0.423331464277593 IGF2/EFNB1/ANXA1/MIF/CD151/CEBPB/HES1 7 GO:0030514 negative regulation of BMP signaling pathway 2/313 52/18722 0.215835663820018 0.423331464277593 HTRA1/FBN1 2 GO:0032206 positive regulation of telomere maintenance 2/313 52/18722 0.215835663820018 0.423331464277593 PPP1R10/MAP3K4 2 GO:0045010 actin nucleation 2/313 52/18722 0.215835663820018 0.423331464277593 SCIN/IQGAP2 2 GO:1903426 regulation of reactive oxygen species biosynthetic process 2/313 52/18722 0.215835663820018 0.423331464277593 PAGE4/RHOA 2 GO:2000378 negative regulation of reactive oxygen species metabolic process 2/313 52/18722 0.215835663820018 0.423331464277593 PAGE4/RHOA 2 GO:0003073 regulation of systemic arterial blood pressure 3/313 96/18722 0.216773968940325 0.424952883499391 RHOA/TPM1/GJA1 3 GO:0043255 regulation of carbohydrate biosynthetic process 3/313 97/18722 0.221149125432919 0.426758614622666 IGF2/INSR/PGP 3 GO:0016925 protein sumoylation 2/313 53/18722 0.221993985794786 0.426758614622666 HMG20B/EGR1 2 GO:0031279 regulation of cyclase activity 2/313 53/18722 0.221993985794786 0.426758614622666 TIMP2/CALM1 2 GO:0033059 cellular pigmentation 2/313 53/18722 0.221993985794786 0.426758614622666 CD63/RAB17 2 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 5/313 193/18722 0.222226759708879 0.426758614622666 IGF2/MIF/TNFRSF1A/ISL1/HES1 5 GO:0000478 endonucleolytic cleavage involved in rRNA processing 1/313 15/18722 0.22352421264975 0.426758614622666 RPS21 1 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/313 15/18722 0.22352421264975 0.426758614622666 RPS21 1 GO:0002070 epithelial cell maturation 1/313 15/18722 0.22352421264975 0.426758614622666 AKR1B1 1 GO:0003356 regulation of cilium beat frequency 1/313 15/18722 0.22352421264975 0.426758614622666 CCSAP 1 GO:0006089 lactate metabolic process 1/313 15/18722 0.22352421264975 0.426758614622666 LDHA 1 GO:0006098 pentose-phosphate shunt 1/313 15/18722 0.22352421264975 0.426758614622666 PGAM1 1 GO:0006704 glucocorticoid biosynthetic process 1/313 15/18722 0.22352421264975 0.426758614622666 CYP11A1 1 GO:0010713 negative regulation of collagen metabolic process 1/313 15/18722 0.22352421264975 0.426758614622666 ERRFI1 1 GO:0010763 positive regulation of fibroblast migration 1/313 15/18722 0.22352421264975 0.426758614622666 ITGB1 1 GO:0010832 negative regulation of myotube differentiation 1/313 15/18722 0.22352421264975 0.426758614622666 BHLHE41 1 GO:0010889 regulation of sequestering of triglyceride 1/313 15/18722 0.22352421264975 0.426758614622666 PLIN2 1 GO:0018146 keratan sulfate biosynthetic process 1/313 15/18722 0.22352421264975 0.426758614622666 B3GNT2 1 GO:0018216 peptidyl-arginine methylation 1/313 15/18722 0.22352421264975 0.426758614622666 PRMT1 1 GO:0019511 peptidyl-proline hydroxylation 1/313 15/18722 0.22352421264975 0.426758614622666 P4HA1 1 GO:0021542 dentate gyrus development 1/313 15/18722 0.22352421264975 0.426758614622666 BTG2 1 GO:0023035 CD40 signaling pathway 1/313 15/18722 0.22352421264975 0.426758614622666 ITGB1 1 GO:0031958 corticosteroid receptor signaling pathway 1/313 15/18722 0.22352421264975 0.426758614622666 NR3C1 1 GO:0032354 response to follicle-stimulating hormone 1/313 15/18722 0.22352421264975 0.426758614622666 TGFBR3 1 GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 1/313 15/18722 0.22352421264975 0.426758614622666 ISL1 1 GO:0033275 actin-myosin filament sliding 1/313 15/18722 0.22352421264975 0.426758614622666 TPM1 1 GO:0033599 regulation of mammary gland epithelial cell proliferation 1/313 15/18722 0.22352421264975 0.426758614622666 GPX1 1 GO:0045064 T-helper 2 cell differentiation 1/313 15/18722 0.22352421264975 0.426758614622666 ANXA1 1 GO:0045986 negative regulation of smooth muscle contraction 1/313 15/18722 0.22352421264975 0.426758614622666 RGS2 1 GO:0046184 aldehyde biosynthetic process 1/313 15/18722 0.22352421264975 0.426758614622666 TPI1 1 GO:0050746 regulation of lipoprotein metabolic process 1/313 15/18722 0.22352421264975 0.426758614622666 DBI 1 GO:0051127 positive regulation of actin nucleation 1/313 15/18722 0.22352421264975 0.426758614622666 SCIN 1 GO:0051791 medium-chain fatty acid metabolic process 1/313 15/18722 0.22352421264975 0.426758614622666 CROT 1 GO:0051938 L-glutamate import 1/313 15/18722 0.22352421264975 0.426758614622666 ITGB1 1 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 1/313 15/18722 0.22352421264975 0.426758614622666 BTG2 1 GO:0060253 negative regulation of glial cell proliferation 1/313 15/18722 0.22352421264975 0.426758614622666 HES1 1 GO:0070207 protein homotrimerization 1/313 15/18722 0.22352421264975 0.426758614622666 MIF 1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade 1/313 15/18722 0.22352421264975 0.426758614622666 FHL2 1 GO:0071871 response to epinephrine 1/313 15/18722 0.22352421264975 0.426758614622666 PDE4B 1 GO:0072044 collecting duct development 1/313 15/18722 0.22352421264975 0.426758614622666 AKR1B1 1 GO:0072224 metanephric glomerulus development 1/313 15/18722 0.22352421264975 0.426758614622666 EGR1 1 GO:0080154 regulation of fertilization 1/313 15/18722 0.22352421264975 0.426758614622666 MYH9 1 GO:0086069 bundle of His cell to Purkinje myocyte communication 1/313 15/18722 0.22352421264975 0.426758614622666 DSP 1 GO:0098712 L-glutamate import across plasma membrane 1/313 15/18722 0.22352421264975 0.426758614622666 ITGB1 1 GO:0098760 response to interleukin-7 1/313 15/18722 0.22352421264975 0.426758614622666 YBX1 1 GO:0098761 cellular response to interleukin-7 1/313 15/18722 0.22352421264975 0.426758614622666 YBX1 1 GO:0106057 negative regulation of calcineurin-mediated signaling 1/313 15/18722 0.22352421264975 0.426758614622666 FHL2 1 GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response 1/313 15/18722 0.22352421264975 0.426758614622666 PPP1R15A 1 GO:1903729 regulation of plasma membrane organization 1/313 15/18722 0.22352421264975 0.426758614622666 MYH9 1 GO:1904424 regulation of GTP binding 1/313 15/18722 0.22352421264975 0.426758614622666 STMN1 1 GO:1905146 lysosomal protein catabolic process 1/313 15/18722 0.22352421264975 0.426758614622666 CLN3 1 GO:2001138 regulation of phospholipid transport 1/313 15/18722 0.22352421264975 0.426758614622666 DBI 1 GO:2001279 regulation of unsaturated fatty acid biosynthetic process 1/313 15/18722 0.22352421264975 0.426758614622666 ANXA1 1 GO:0050777 negative regulation of immune response 5/313 194/18722 0.225259243335921 0.429855608711704 HTRA1/SERPINB9/ANXA1/GPX1/PLK2 5 GO:0070663 regulation of leukocyte proliferation 6/313 245/18722 0.227838348988479 0.43453157980618 IGF2/EFNB1/ANXA1/MIF/CEBPB/HES1 6 GO:0006584 catecholamine metabolic process 2/313 54/18722 0.228166174949449 0.43453157980618 LY6E/AKR1B1 2 GO:0009712 catechol-containing compound metabolic process 2/313 54/18722 0.228166174949449 0.43453157980618 LY6E/AKR1B1 2 GO:0070839 metal ion export 2/313 54/18722 0.228166174949449 0.43453157980618 ATP2B1/CALM1 2 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 3/313 99/18722 0.22995182136915 0.437095301717036 MIF/TNFRSF1A/CLU 3 GO:0015837 amine transport 3/313 99/18722 0.22995182136915 0.437095301717036 ITGB1/SLC43A2/RGS2 3 GO:0021510 spinal cord development 3/313 99/18722 0.22995182136915 0.437095301717036 LMO4/ISL1/SOX4 3 GO:0031668 cellular response to extracellular stimulus 6/313 246/18722 0.230544188484119 0.437095301717036 PMAIP1/FOS/ATP2B1/JUN/STK24/SLC2A1 6 GO:0016331 morphogenesis of embryonic epithelium 4/313 147/18722 0.231947408439545 0.437095301717036 LMO4/PFN1/SOX4/BRD2 4 GO:0000768 syncytium formation by plasma membrane fusion 2/313 55/18722 0.234350054659716 0.437095301717036 ADAM12/MYH9 2 GO:0031113 regulation of microtubule polymerization 2/313 55/18722 0.234350054659716 0.437095301717036 HSPA1A/STMN1 2 GO:0043331 response to dsRNA 2/313 55/18722 0.234350054659716 0.437095301717036 CAV1/PMAIP1 2 GO:0045620 negative regulation of lymphocyte differentiation 2/313 55/18722 0.234350054659716 0.437095301717036 ANXA1/ID2 2 GO:0140253 cell-cell fusion 2/313 55/18722 0.234350054659716 0.437095301717036 ADAM12/MYH9 2 GO:0060840 artery development 3/313 100/18722 0.2343776109724 0.437095301717036 ADAMTS6/SOX4/HES1 3 GO:0061640 cytoskeleton-dependent cytokinesis 3/313 100/18722 0.2343776109724 0.437095301717036 RHOA/STMN1/RHOB 3 GO:0042594 response to starvation 5/313 197/18722 0.23442978459931 0.437095301717036 PAGE4/PMAIP1/JUN/STK24/SLC2A1 5 GO:1901990 regulation of mitotic cell cycle phase transition 7/313 299/18722 0.235182704232043 0.437095301717036 NEK6/ANXA1/SOX4/ADAMTS1/PLK2/ID2/CCNB1 7 GO:0035148 tube formation 4/313 148/18722 0.23553164194881 0.437095301717036 LMO4/PFN1/SOX4/BRD2 4 GO:0044272 sulfur compound biosynthetic process 4/313 148/18722 0.23553164194881 0.437095301717036 SLC26A2/MPC2/TECR/B3GNT2 4 GO:2001056 positive regulation of cysteine-type endopeptidase activity 4/313 148/18722 0.23553164194881 0.437095301717036 PMAIP1/PDCD6/RHOA/LGMN 4 GO:0001845 phagolysosome assembly 1/313 16/18722 0.236515976237745 0.437095301717036 CLN3 1 GO:0001977 renal system process involved in regulation of blood volume 1/313 16/18722 0.236515976237745 0.437095301717036 GJA1 1 GO:0003084 positive regulation of systemic arterial blood pressure 1/313 16/18722 0.236515976237745 0.437095301717036 RHOA 1 GO:0006266 DNA ligation 1/313 16/18722 0.236515976237745 0.437095301717036 TOP2A 1 GO:0006740 NADPH regeneration 1/313 16/18722 0.236515976237745 0.437095301717036 PGAM1 1 GO:0009299 mRNA transcription 1/313 16/18722 0.236515976237745 0.437095301717036 DDX5 1 GO:0009642 response to light intensity 1/313 16/18722 0.236515976237745 0.437095301717036 RDH13 1 GO:0010225 response to UV-C 1/313 16/18722 0.236515976237745 0.437095301717036 MAP3K4 1 GO:0017014 protein nitrosylation 1/313 16/18722 0.236515976237745 0.437095301717036 GAPDH 1 GO:0018119 peptidyl-cysteine S-nitrosylation 1/313 16/18722 0.236515976237745 0.437095301717036 GAPDH 1 GO:0019081 viral translation 1/313 16/18722 0.236515976237745 0.437095301717036 SSB 1 GO:0021535 cell migration in hindbrain 1/313 16/18722 0.236515976237745 0.437095301717036 ITGB1 1 GO:0030033 microvillus assembly 1/313 16/18722 0.236515976237745 0.437095301717036 EZR 1 GO:0032274 gonadotropin secretion 1/313 16/18722 0.236515976237745 0.437095301717036 GJA1 1 GO:0033631 cell-cell adhesion mediated by integrin 1/313 16/18722 0.236515976237745 0.437095301717036 ITGB1 1 GO:0034138 toll-like receptor 3 signaling pathway 1/313 16/18722 0.236515976237745 0.437095301717036 CAV1 1 GO:0035751 regulation of lysosomal lumen pH 1/313 16/18722 0.236515976237745 0.437095301717036 CLN3 1 GO:0042574 retinal metabolic process 1/313 16/18722 0.236515976237745 0.437095301717036 RDH13 1 GO:0042795 snRNA transcription by RNA polymerase II 1/313 16/18722 0.236515976237745 0.437095301717036 ICE1 1 GO:0043923 positive regulation by host of viral transcription 1/313 16/18722 0.236515976237745 0.437095301717036 JUN 1 GO:0044849 estrous cycle 1/313 16/18722 0.236515976237745 0.437095301717036 EGR1 1 GO:0045651 positive regulation of macrophage differentiation 1/313 16/18722 0.236515976237745 0.437095301717036 ID2 1 GO:0045721 negative regulation of gluconeogenesis 1/313 16/18722 0.236515976237745 0.437095301717036 PGP 1 GO:0048557 embryonic digestive tract morphogenesis 1/313 16/18722 0.236515976237745 0.437095301717036 ID2 1 GO:0050884 neuromuscular process controlling posture 1/313 16/18722 0.236515976237745 0.437095301717036 TMEM150C 1 GO:0061548 ganglion development 1/313 16/18722 0.236515976237745 0.437095301717036 NRP2 1 GO:0061684 chaperone-mediated autophagy 1/313 16/18722 0.236515976237745 0.437095301717036 CLU 1 GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 1/313 16/18722 0.236515976237745 0.437095301717036 HSPA1A 1 GO:0071361 cellular response to ethanol 1/313 16/18722 0.236515976237745 0.437095301717036 DNMT3A 1 GO:0071391 cellular response to estrogen stimulus 1/313 16/18722 0.236515976237745 0.437095301717036 SERPINB9 1 GO:0072109 glomerular mesangium development 1/313 16/18722 0.236515976237745 0.437095301717036 EGR1 1 GO:0090231 regulation of spindle checkpoint 1/313 16/18722 0.236515976237745 0.437095301717036 CCNB1 1 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint 1/313 16/18722 0.236515976237745 0.437095301717036 CCNB1 1 GO:0090520 sphingolipid mediated signaling pathway 1/313 16/18722 0.236515976237745 0.437095301717036 EZR 1 GO:0097202 activation of cysteine-type endopeptidase activity 1/313 16/18722 0.236515976237745 0.437095301717036 LGMN 1 GO:0099116 tRNA 5'-end processing 1/313 16/18722 0.236515976237745 0.437095301717036 SSB 1 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration 1/313 16/18722 0.236515976237745 0.437095301717036 ATP2B1 1 GO:1901163 regulation of trophoblast cell migration 1/313 16/18722 0.236515976237745 0.437095301717036 GJA1 1 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/313 16/18722 0.236515976237745 0.437095301717036 MIF 1 GO:1903504 regulation of mitotic spindle checkpoint 1/313 16/18722 0.236515976237745 0.437095301717036 CCNB1 1 GO:1904683 regulation of metalloendopeptidase activity 1/313 16/18722 0.236515976237745 0.437095301717036 TIMP3 1 GO:1905906 regulation of amyloid fibril formation 1/313 16/18722 0.236515976237745 0.437095301717036 CLU 1 GO:2000001 regulation of DNA damage checkpoint 1/313 16/18722 0.236515976237745 0.437095301717036 PPP1R10 1 GO:2001044 regulation of integrin-mediated signaling pathway 1/313 16/18722 0.236515976237745 0.437095301717036 CD63 1 GO:0006576 cellular biogenic amine metabolic process 3/313 101/18722 0.238818543203901 0.440922499504001 LY6E/OAZ1/AKR1B1 3 GO:0048024 regulation of mRNA splicing, via spliceosome 3/313 101/18722 0.238818543203901 0.440922499504001 DDX5/PRDX6/TRA2B 3 GO:0016525 negative regulation of angiogenesis 4/313 149/18722 0.239129170458041 0.441281993181658 SERPINE1/PGK1/ADAMTS1/PLK2 4 GO:0006066 alcohol metabolic process 8/313 353/18722 0.239866915375388 0.442428947109546 TPI1/RDH13/CYP11A1/IDH1/DHCR24/AKR1B1/ISYNA1/PGP 8 GO:0002090 regulation of receptor internalization 2/313 56/18722 0.240543516758499 0.442818746759964 CD63/INSR 2 GO:0015800 acidic amino acid transport 2/313 56/18722 0.240543516758499 0.442818746759964 ITGB1/GJA1 2 GO:0043470 regulation of carbohydrate catabolic process 2/313 56/18722 0.240543516758499 0.442818746759964 PGAM1/INSR 2 GO:0046456 icosanoid biosynthetic process 2/313 56/18722 0.240543516758499 0.442818746759964 ANXA1/MIF 2 GO:0006672 ceramide metabolic process 3/313 102/18722 0.243273765595473 0.447196149503605 ORMDL1/SPTSSA/ITGB8 3 GO:0034308 primary alcohol metabolic process 3/313 102/18722 0.243273765595473 0.447196149503605 RDH13/CYP11A1/AKR1B1 3 GO:1902106 negative regulation of leukocyte differentiation 3/313 102/18722 0.243273765595473 0.447196149503605 FBN1/ANXA1/ID2 3 GO:0048592 eye morphogenesis 4/313 151/18722 0.246362292839763 0.447243648054372 RDH13/FBN1/C12orf57/MFAP5 4 GO:1904064 positive regulation of cation transmembrane transport 4/313 151/18722 0.246362292839763 0.447243648054372 GSTO1/SRI/TMSB4X/CALM1 4 GO:2000181 negative regulation of blood vessel morphogenesis 4/313 151/18722 0.246362292839763 0.447243648054372 SERPINE1/PGK1/ADAMTS1/PLK2 4 GO:0010883 regulation of lipid storage 2/313 57/18722 0.246744519867796 0.447243648054372 PLIN2/MEST 2 GO:0050879 multicellular organismal movement 2/313 57/18722 0.246744519867796 0.447243648054372 GSTO1/C12orf57 2 GO:0050881 musculoskeletal movement 2/313 57/18722 0.246744519867796 0.447243648054372 GSTO1/C12orf57 2 GO:0051785 positive regulation of nuclear division 2/313 57/18722 0.246744519867796 0.447243648054372 IGF2/INSR 2 GO:0061756 leukocyte adhesion to vascular endothelial cell 2/313 57/18722 0.246744519867796 0.447243648054372 RHOA/ITGB1 2 GO:1900024 regulation of substrate adhesion-dependent cell spreading 2/313 57/18722 0.246744519867796 0.447243648054372 FBLN1/S100A10 2 GO:0002696 positive regulation of leukocyte activation 9/313 409/18722 0.247086807056806 0.447243648054372 IGF2/CAV1/EFNB1/ANXA1/MIF/SOX4/RHOA/CTSC/HES1 9 GO:0006325 chromatin organization 9/313 409/18722 0.247086807056806 0.447243648054372 MBD3/GPX4/SMARCA1/HMG20B/ACTB/HMGN3/NR3C1/DNMT3A/BRD2 9 GO:0030148 sphingolipid biosynthetic process 3/313 103/18722 0.247742435006293 0.447243648054372 ORMDL1/HACD3/SPTSSA 3 GO:0046425 regulation of receptor signaling pathway via JAK-STAT 3/313 103/18722 0.247742435006293 0.447243648054372 CAV1/AKR1B1/HES1 3 GO:0050773 regulation of dendrite development 3/313 103/18722 0.247742435006293 0.447243648054372 RAB17/RHOA/CDC20 3 GO:0001818 negative regulation of cytokine production 8/313 357/18722 0.249086621583902 0.447243648054372 ANXA4/FN1/ANXA1/ATP2B1/SERPINB1/EZR/TMSB4X/ERRFI1 8 GO:0006474 N-terminal protein amino acid acetylation 1/313 17/18722 0.249291048377036 0.447243648054372 SOX4 1 GO:0006577 amino-acid betaine metabolic process 1/313 17/18722 0.249291048377036 0.447243648054372 CROT 1 GO:0006901 vesicle coating 1/313 17/18722 0.249291048377036 0.447243648054372 PDCD6 1 GO:0008334 histone mRNA metabolic process 1/313 17/18722 0.249291048377036 0.447243648054372 SSB 1 GO:0009084 glutamine family amino acid biosynthetic process 1/313 17/18722 0.249291048377036 0.447243648054372 CLN3 1 GO:0010566 regulation of ketone biosynthetic process 1/313 17/18722 0.249291048377036 0.447243648054372 EGR1 1 GO:0010612 regulation of cardiac muscle adaptation 1/313 17/18722 0.249291048377036 0.447243648054372 ERRFI1 1 GO:0015867 ATP transport 1/313 17/18722 0.249291048377036 0.447243648054372 GJA1 1 GO:0020027 hemoglobin metabolic process 1/313 17/18722 0.249291048377036 0.447243648054372 PRMT1 1 GO:0032604 granulocyte macrophage colony-stimulating factor production 1/313 17/18722 0.249291048377036 0.447243648054372 ISL1 1 GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 1/313 17/18722 0.249291048377036 0.447243648054372 ISL1 1 GO:0035729 cellular response to hepatocyte growth factor stimulus 1/313 17/18722 0.249291048377036 0.447243648054372 LGMN 1 GO:0036035 osteoclast development 1/313 17/18722 0.249291048377036 0.447243648054372 FBN1 1 GO:0042339 keratan sulfate metabolic process 1/313 17/18722 0.249291048377036 0.447243648054372 B3GNT2 1 GO:0042448 progesterone metabolic process 1/313 17/18722 0.249291048377036 0.447243648054372 EGR1 1 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 1/313 17/18722 0.249291048377036 0.447243648054372 CAV1 1 GO:0043968 histone H2A acetylation 1/313 17/18722 0.249291048377036 0.447243648054372 MORF4L2 1 GO:0045198 establishment of epithelial cell apical/basal polarity 1/313 17/18722 0.249291048377036 0.447243648054372 RHOA 1 GO:0045815 positive regulation of gene expression, epigenetic 1/313 17/18722 0.249291048377036 0.447243648054372 SERTAD1 1 GO:0048521 negative regulation of behavior 1/313 17/18722 0.249291048377036 0.447243648054372 ARRDC3 1 GO:0048532 anatomical structure arrangement 1/313 17/18722 0.249291048377036 0.447243648054372 NRP2 1 GO:0051580 regulation of neurotransmitter uptake 1/313 17/18722 0.249291048377036 0.447243648054372 ITGB1 1 GO:0051797 regulation of hair follicle development 1/313 17/18722 0.249291048377036 0.447243648054372 FERMT1 1 GO:0060033 anatomical structure regression 1/313 17/18722 0.249291048377036 0.447243648054372 FLT1 1 GO:0060263 regulation of respiratory burst 1/313 17/18722 0.249291048377036 0.447243648054372 INSR 1 GO:0060977 coronary vasculature morphogenesis 1/313 17/18722 0.249291048377036 0.447243648054372 TGFBR3 1 GO:0061298 retina vasculature development in camera-type eye 1/313 17/18722 0.249291048377036 0.447243648054372 CLIC4 1 GO:0061450 trophoblast cell migration 1/313 17/18722 0.249291048377036 0.447243648054372 GJA1 1 GO:0070206 protein trimerization 1/313 17/18722 0.249291048377036 0.447243648054372 MIF 1 GO:0070593 dendrite self-avoidance 1/313 17/18722 0.249291048377036 0.447243648054372 BSG 1 GO:0090136 epithelial cell-cell adhesion 1/313 17/18722 0.249291048377036 0.447243648054372 DSP 1 GO:0090399 replicative senescence 1/313 17/18722 0.249291048377036 0.447243648054372 SERPINE1 1 GO:1901550 regulation of endothelial cell development 1/313 17/18722 0.249291048377036 0.447243648054372 TNFRSF1A 1 GO:1903140 regulation of establishment of endothelial barrier 1/313 17/18722 0.249291048377036 0.447243648054372 TNFRSF1A 1 GO:1903242 regulation of cardiac muscle hypertrophy in response to stress 1/313 17/18722 0.249291048377036 0.447243648054372 ERRFI1 1 GO:1904355 positive regulation of telomere capping 1/313 17/18722 0.249291048377036 0.447243648054372 MAP3K4 1 GO:0000819 sister chromatid segregation 5/313 202/18722 0.249940681347457 0.447666277667125 NEK6/PTTG1/CDC20/TOP2A/CCNB1 5 GO:0032388 positive regulation of intracellular transport 5/313 202/18722 0.249940681347457 0.447666277667125 TCAF1/ICE1/OAZ1/EZR/NMT1 5 GO:0016125 sterol metabolic process 4/313 152/18722 0.249996980908933 0.447666277667125 CYP11A1/CYP19A1/DHCR24/CYB5R1 4 GO:1901343 negative regulation of vasculature development 4/313 152/18722 0.249996980908933 0.447666277667125 SERPINE1/PGK1/ADAMTS1/PLK2 4 GO:0006892 post-Golgi vesicle-mediated transport 3/313 104/18722 0.252223717795246 0.451046740575482 KRT18/CLN3/EXOC1 3 GO:0045621 positive regulation of lymphocyte differentiation 3/313 104/18722 0.252223717795246 0.451046740575482 ANXA1/SOX4/RHOA 3 GO:0006826 iron ion transport 2/313 58/18722 0.252951087766917 0.451046740575482 FTL/FTH1 2 GO:0018208 peptidyl-proline modification 2/313 58/18722 0.252951087766917 0.451046740575482 P4HA1/FKBP8 2 GO:0043525 positive regulation of neuron apoptotic process 2/313 58/18722 0.252951087766917 0.451046740575482 JUN/RHOA 2 GO:0043666 regulation of phosphoprotein phosphatase activity 2/313 58/18722 0.252951087766917 0.451046740575482 CALM1/PPP1R15A 2 GO:0045604 regulation of epidermal cell differentiation 2/313 58/18722 0.252951087766917 0.451046740575482 ERRFI1/HES1 2 GO:1902808 positive regulation of cell cycle G1/S phase transition 2/313 58/18722 0.252951087766917 0.451046740575482 ANXA1/ADAMTS1 2 GO:2000736 regulation of stem cell differentiation 2/313 58/18722 0.252951087766917 0.451046740575482 LBH/HES1 2 GO:0007338 single fertilization 4/313 153/18722 0.253643152623551 0.452069045897875 ALDOA/LY6K/MYH9/SPESP1 4 GO:0006767 water-soluble vitamin metabolic process 2/313 59/18722 0.259161307796329 0.456235465654785 GSTO1/SLC2A1 2 GO:0030042 actin filament depolymerization 2/313 59/18722 0.259161307796329 0.456235465654785 CFL1/SCIN 2 GO:0032768 regulation of monooxygenase activity 2/313 59/18722 0.259161307796329 0.456235465654785 CAV1/CALM1 2 GO:0035306 positive regulation of dephosphorylation 2/313 59/18722 0.259161307796329 0.456235465654785 CALM1/PPP1R15A 2 GO:0043407 negative regulation of MAP kinase activity 2/313 59/18722 0.259161307796329 0.456235465654785 CAV1/RGS2 2 GO:0048278 vesicle docking 2/313 59/18722 0.259161307796329 0.456235465654785 CAV2/CLN3 2 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 2/313 59/18722 0.259161307796329 0.456235465654785 CAV1/ERRFI1 2 GO:0060348 bone development 5/313 205/18722 0.259370755783673 0.456235465654785 FBN1/HSD17B1/RHOA/GJA1/TMEM107 5 GO:0051251 positive regulation of lymphocyte activation 8/313 362/18722 0.260769864949829 0.456235465654785 IGF2/CAV1/EFNB1/ANXA1/MIF/SOX4/RHOA/HES1 8 GO:0006606 protein import into nucleus 4/313 155/18722 0.260968155730353 0.456235465654785 RPL23/PTTG1IP/PPP1R10/FERMT1 4 GO:0010970 transport along microtubule 4/313 155/18722 0.260968155730353 0.456235465654785 ARMCX3/DST/HSPB1/CLN3 4 GO:0006906 vesicle fusion 3/313 106/18722 0.261220837389763 0.456235465654785 ANXA1/CAV2/CLN3 3 GO:0042116 macrophage activation 3/313 106/18722 0.261220837389763 0.456235465654785 MIF/CTSC/CLU 3 GO:1903707 negative regulation of hemopoiesis 3/313 106/18722 0.261220837389763 0.456235465654785 FBN1/ANXA1/ID2 3 GO:0000712 resolution of meiotic recombination intermediates 1/313 18/18722 0.261853031903259 0.456235465654785 TOP2A 1 GO:0002544 chronic inflammatory response 1/313 18/18722 0.261853031903259 0.456235465654785 GJA1 1 GO:0003128 heart field specification 1/313 18/18722 0.261853031903259 0.456235465654785 ISL1 1 GO:0006085 acetyl-CoA biosynthetic process 1/313 18/18722 0.261853031903259 0.456235465654785 MPC2 1 GO:0006103 2-oxoglutarate metabolic process 1/313 18/18722 0.261853031903259 0.456235465654785 IDH1 1 GO:0006415 translational termination 1/313 18/18722 0.261853031903259 0.456235465654785 EIF5A 1 GO:0006595 polyamine metabolic process 1/313 18/18722 0.261853031903259 0.456235465654785 OAZ1 1 GO:0015936 coenzyme A metabolic process 1/313 18/18722 0.261853031903259 0.456235465654785 CROT 1 GO:0019896 axonal transport of mitochondrion 1/313 18/18722 0.261853031903259 0.456235465654785 ARMCX3 1 GO:0030730 sequestering of triglyceride 1/313 18/18722 0.261853031903259 0.456235465654785 PLIN2 1 GO:0031649 heat generation 1/313 18/18722 0.261853031903259 0.456235465654785 ARRDC3 1 GO:0032769 negative regulation of monooxygenase activity 1/313 18/18722 0.261853031903259 0.456235465654785 CAV1 1 GO:0033189 response to vitamin A 1/313 18/18722 0.261853031903259 0.456235465654785 DNMT3A 1 GO:0036499 PERK-mediated unfolded protein response 1/313 18/18722 0.261853031903259 0.456235465654785 PPP1R15A 1 GO:0045623 negative regulation of T-helper cell differentiation 1/313 18/18722 0.261853031903259 0.456235465654785 ANXA1 1 GO:0045653 negative regulation of megakaryocyte differentiation 1/313 18/18722 0.261853031903259 0.456235465654785 PRMT1 1 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 1/313 18/18722 0.261853031903259 0.456235465654785 SERPINB9 1 GO:0048268 clathrin coat assembly 1/313 18/18722 0.261853031903259 0.456235465654785 CLTB 1 GO:0048643 positive regulation of skeletal muscle tissue development 1/313 18/18722 0.261853031903259 0.456235465654785 IGF2 1 GO:0060391 positive regulation of SMAD protein signal transduction 1/313 18/18722 0.261853031903259 0.456235465654785 PARP1 1 GO:0060716 labyrinthine layer blood vessel development 1/313 18/18722 0.261853031903259 0.456235465654785 HES1 1 GO:0060749 mammary gland alveolus development 1/313 18/18722 0.261853031903259 0.456235465654785 ID2 1 GO:0061377 mammary gland lobule development 1/313 18/18722 0.261853031903259 0.456235465654785 ID2 1 GO:0061484 hematopoietic stem cell homeostasis 1/313 18/18722 0.261853031903259 0.456235465654785 SOX4 1 GO:0071071 regulation of phospholipid biosynthetic process 1/313 18/18722 0.261853031903259 0.456235465654785 IDH1 1 GO:0071360 cellular response to exogenous dsRNA 1/313 18/18722 0.261853031903259 0.456235465654785 CAV1 1 GO:0071800 podosome assembly 1/313 18/18722 0.261853031903259 0.456235465654785 RHOA 1 GO:0072234 metanephric nephron tubule development 1/313 18/18722 0.261853031903259 0.456235465654785 HES1 1 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis 1/313 18/18722 0.261853031903259 0.456235465654785 MAGED1 1 GO:0090493 catecholamine uptake 1/313 18/18722 0.261853031903259 0.456235465654785 ACTB 1 GO:0097094 craniofacial suture morphogenesis 1/313 18/18722 0.261853031903259 0.456235465654785 TMEM107 1 GO:0150078 positive regulation of neuroinflammatory response 1/313 18/18722 0.261853031903259 0.456235465654785 CTSC 1 GO:1900242 regulation of synaptic vesicle endocytosis 1/313 18/18722 0.261853031903259 0.456235465654785 CALM1 1 GO:1902001 fatty acid transmembrane transport 1/313 18/18722 0.261853031903259 0.456235465654785 SLC2A1 1 GO:2000641 regulation of early endosome to late endosome transport 1/313 18/18722 0.261853031903259 0.456235465654785 EZR 1 GO:0017038 protein import 5/313 206/18722 0.26253300576706 0.457210957436046 RPL23/PTTG1IP/PPP1R10/CLU/FERMT1 5 GO:0031348 negative regulation of defense response 6/313 258/18722 0.263757872048166 0.459134073565326 HTRA1/SERPINB9/GPX1/TNFRSF1A/ISL1/PLK2 6 GO:0009267 cellular response to starvation 4/313 156/18722 0.264646096717667 0.460469693877587 PMAIP1/JUN/STK24/SLC2A1 4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 2/313 60/18722 0.265373329296371 0.460892456492374 DDX5/TRA2B 2 GO:0009620 response to fungus 2/313 60/18722 0.265373329296371 0.460892456492374 GAPDH/COTL1 2 GO:0030071 regulation of mitotic metaphase/anaphase transition 2/313 60/18722 0.265373329296371 0.460892456492374 NEK6/CCNB1 2 GO:0061951 establishment of protein localization to plasma membrane 2/313 60/18722 0.265373329296371 0.460892456492374 KRT18/CLN3 2 GO:0019221 cytokine-mediated signaling pathway 10/313 472/18722 0.267015195432356 0.463532534888728 KRT8/CAV1/KRT18/TNFRSF1A/CSF3R/TMSB4X/HSPA1A/EIF5A/CSF2RA/EGR1 10 GO:0007034 vacuolar transport 4/313 157/18722 0.2683337407639 0.465609184634535 HSPA1A/CLN3/RHOB/CLU 4 GO:0050867 positive regulation of cell activation 9/313 420/18722 0.271155171179685 0.46727852464481 IGF2/CAV1/EFNB1/ANXA1/MIF/SOX4/RHOA/CTSC/HES1 9 GO:0006900 vesicle budding from membrane 2/313 61/18722 0.271585362080144 0.46727852464481 PDCD6/S100A10 2 GO:0030199 collagen fibril organization 2/313 61/18722 0.271585362080144 0.46727852464481 P4HA1/COL14A1 2 GO:0043030 regulation of macrophage activation 2/313 61/18722 0.271585362080144 0.46727852464481 MIF/CTSC 2 GO:1904356 regulation of telomere maintenance via telomere lengthening 2/313 61/18722 0.271585362080144 0.46727852464481 PARP1/MAP3K4 2 GO:0043488 regulation of mRNA stability 4/313 158/18722 0.272030648387225 0.46727852464481 YBX3/FUS/YBX1/BTG2 4 GO:0002523 leukocyte migration involved in inflammatory response 1/313 19/18722 0.274205469938667 0.46727852464481 JAM3 1 GO:0002716 negative regulation of natural killer cell mediated immunity 1/313 19/18722 0.274205469938667 0.46727852464481 SERPINB9 1 GO:0006007 glucose catabolic process 1/313 19/18722 0.274205469938667 0.46727852464481 ENO1 1 GO:0006044 N-acetylglucosamine metabolic process 1/313 19/18722 0.274205469938667 0.46727852464481 EXTL2 1 GO:0007039 protein catabolic process in the vacuole 1/313 19/18722 0.274205469938667 0.46727852464481 CLN3 1 GO:0007530 sex determination 1/313 19/18722 0.274205469938667 0.46727852464481 MAP3K4 1 GO:0007603 phototransduction, visible light 1/313 19/18722 0.274205469938667 0.46727852464481 NMT1 1 GO:0009301 snRNA transcription 1/313 19/18722 0.274205469938667 0.46727852464481 ICE1 1 GO:0010002 cardioblast differentiation 1/313 19/18722 0.274205469938667 0.46727852464481 ISL1 1 GO:0010738 regulation of protein kinase A signaling 1/313 19/18722 0.274205469938667 0.46727852464481 MIF 1 GO:0015802 basic amino acid transport 1/313 19/18722 0.274205469938667 0.46727852464481 CLN3 1 GO:0019373 epoxygenase P450 pathway 1/313 19/18722 0.274205469938667 0.46727852464481 CYP2J2 1 GO:0030011 maintenance of cell polarity 1/313 19/18722 0.274205469938667 0.46727852464481 DST 1 GO:0030220 platelet formation 1/313 19/18722 0.274205469938667 0.46727852464481 MYH9 1 GO:0031290 retinal ganglion cell axon guidance 1/313 19/18722 0.274205469938667 0.46727852464481 ISL1 1 GO:0035313 wound healing, spreading of epidermal cells 1/313 19/18722 0.274205469938667 0.46727852464481 FERMT1 1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process 1/313 19/18722 0.274205469938667 0.46727852464481 TECR 1 GO:0035728 response to hepatocyte growth factor 1/313 19/18722 0.274205469938667 0.46727852464481 LGMN 1 GO:0036344 platelet morphogenesis 1/313 19/18722 0.274205469938667 0.46727852464481 MYH9 1 GO:0042474 middle ear morphogenesis 1/313 19/18722 0.274205469938667 0.46727852464481 RPL38 1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate 1/313 19/18722 0.274205469938667 0.46727852464481 TOP2A 1 GO:0045821 positive regulation of glycolytic process 1/313 19/18722 0.274205469938667 0.46727852464481 INSR 1 GO:0046716 muscle cell cellular homeostasis 1/313 19/18722 0.274205469938667 0.46727852464481 ALDOA 1 GO:0051444 negative regulation of ubiquitin-protein transferase activity 1/313 19/18722 0.274205469938667 0.46727852464481 RPL23 1 GO:0051546 keratinocyte migration 1/313 19/18722 0.274205469938667 0.46727852464481 FERMT1 1 GO:0051957 positive regulation of amino acid transport 1/313 19/18722 0.274205469938667 0.46727852464481 ITGB1 1 GO:0070262 peptidyl-serine dephosphorylation 1/313 19/18722 0.274205469938667 0.46727852464481 PPP1R15A 1 GO:0086014 atrial cardiac muscle cell action potential 1/313 19/18722 0.274205469938667 0.46727852464481 GJA1 1 GO:0086026 atrial cardiac muscle cell to AV node cell signaling 1/313 19/18722 0.274205469938667 0.46727852464481 GJA1 1 GO:0086066 atrial cardiac muscle cell to AV node cell communication 1/313 19/18722 0.274205469938667 0.46727852464481 GJA1 1 GO:1900221 regulation of amyloid-beta clearance 1/313 19/18722 0.274205469938667 0.46727852464481 CLU 1 GO:1903978 regulation of microglial cell activation 1/313 19/18722 0.274205469938667 0.46727852464481 CTSC 1 GO:2000269 regulation of fibroblast apoptotic process 1/313 19/18722 0.274205469938667 0.46727852464481 STK17A 1 GO:2000369 regulation of clathrin-dependent endocytosis 1/313 19/18722 0.274205469938667 0.46727852464481 AAK1 1 GO:0043266 regulation of potassium ion transport 3/313 109/18722 0.274790839127789 0.468066543427066 CAV1/CD63/ITGB1 3 GO:0051170 import into nucleus 4/313 159/18722 0.275736382582747 0.469467087876796 RPL23/PTTG1IP/PPP1R10/FERMT1 4 GO:0007091 metaphase/anaphase transition of mitotic cell cycle 2/313 62/18722 0.277795674939866 0.471707464092805 NEK6/CCNB1 2 GO:0032757 positive regulation of interleukin-8 production 2/313 62/18722 0.277795674939866 0.471707464092805 SERPINE1/HSPA1A 2 GO:0032835 glomerulus development 2/313 62/18722 0.277795674939866 0.471707464092805 EGR1/HES1 2 GO:0048663 neuron fate commitment 2/313 62/18722 0.277795674939866 0.471707464092805 ISL1/ID2 2 GO:0060113 inner ear receptor cell differentiation 2/313 62/18722 0.277795674939866 0.471707464092805 MCOLN3/HES1 2 GO:0060675 ureteric bud morphogenesis 2/313 62/18722 0.277795674939866 0.471707464092805 MAGED1/HES1 2 GO:0043491 protein kinase B signaling 5/313 211/18722 0.278473263613101 0.472647220051304 IGF2/GPX1/PDCD6/INSR/ITGB1 5 GO:0002698 negative regulation of immune effector process 3/313 110/18722 0.279330846400368 0.473461543153596 SERPINB9/ANXA1/TMBIM6 3 GO:0009408 response to heat 3/313 110/18722 0.279330846400368 0.473461543153596 PDCD6/HSPA1A/DNAJB4 3 GO:0090174 organelle membrane fusion 3/313 110/18722 0.279330846400368 0.473461543153596 ANXA1/CAV2/CLN3 3 GO:0090316 positive regulation of intracellular protein transport 4/313 160/18722 0.27945050892202 0.473461543153596 TCAF1/ICE1/OAZ1/NMT1 4 GO:0006457 protein folding 5/313 212/18722 0.281685153273226 0.477035310725609 FKBP8/HSPA1A/HSPB1/DNAJB4/CLU 5 GO:0001654 eye development 8/313 371/18722 0.282201572813888 0.477294869118723 RDH13/FBN1/ATP2B1/CLIC4/C12orf57/FKBP8/FLT1/MFAP5 8 GO:0043410 positive regulation of MAPK cascade 10/313 480/18722 0.283794420956541 0.477294869118723 IGF2/TIMP2/MIF/GADD45B/CAV2/INSR/PRMT1/MAGED1/FLT1/MAP3K4 10 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 3/313 111/18722 0.283877909546257 0.477294869118723 FN1/INSR/FLT1 3 GO:0090288 negative regulation of cellular response to growth factor stimulus 3/313 111/18722 0.283877909546257 0.477294869118723 HTRA1/FBN1/PDCD6 3 GO:0050854 regulation of antigen receptor-mediated signaling pathway 2/313 63/18722 0.284002594186003 0.477294869118723 PHPT1/EZR 2 GO:0072171 mesonephric tubule morphogenesis 2/313 63/18722 0.284002594186003 0.477294869118723 MAGED1/HES1 2 GO:1902099 regulation of metaphase/anaphase transition of cell cycle 2/313 63/18722 0.284002594186003 0.477294869118723 NEK6/CCNB1 2 GO:2000242 negative regulation of reproductive process 2/313 63/18722 0.284002594186003 0.477294869118723 MYH9/GJA1 2 GO:2000756 regulation of peptidyl-lysine acetylation 2/313 63/18722 0.284002594186003 0.477294869118723 ISL1/SOX4 2 GO:0007204 positive regulation of cytosolic calcium ion concentration 7/313 319/18722 0.28617359496725 0.477294869118723 CAV1/GSTO1/SRI/TMBIM6/CALM1/GJA1/MCOLN3 7 GO:0002115 store-operated calcium entry 1/313 20/18722 0.286351846878687 0.477294869118723 SARAF 1 GO:0006448 regulation of translational elongation 1/313 20/18722 0.286351846878687 0.477294869118723 EIF5A 1 GO:0006525 arginine metabolic process 1/313 20/18722 0.286351846878687 0.477294869118723 CLN3 1 GO:0006896 Golgi to vacuole transport 1/313 20/18722 0.286351846878687 0.477294869118723 CLN3 1 GO:0010801 negative regulation of peptidyl-threonine phosphorylation 1/313 20/18722 0.286351846878687 0.477294869118723 CALM1 1 GO:0014047 glutamate secretion 1/313 20/18722 0.286351846878687 0.477294869118723 GJA1 1 GO:0021516 dorsal spinal cord development 1/313 20/18722 0.286351846878687 0.477294869118723 LMO4 1 GO:0031645 negative regulation of nervous system process 1/313 20/18722 0.286351846878687 0.477294869118723 CTSC 1 GO:0032986 protein-DNA complex disassembly 1/313 20/18722 0.286351846878687 0.477294869118723 RPL23 1 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate 1/313 20/18722 0.286351846878687 0.477294869118723 TOP2A 1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process 1/313 20/18722 0.286351846878687 0.477294869118723 ITM2B 1 GO:0043046 DNA methylation involved in gamete generation 1/313 20/18722 0.286351846878687 0.477294869118723 DNMT3A 1 GO:0043555 regulation of translation in response to stress 1/313 20/18722 0.286351846878687 0.477294869118723 PPP1R15A 1 GO:0043651 linoleic acid metabolic process 1/313 20/18722 0.286351846878687 0.477294869118723 CYP2J2 1 GO:0043691 reverse cholesterol transport 1/313 20/18722 0.286351846878687 0.477294869118723 CLU 1 GO:0045063 T-helper 1 cell differentiation 1/313 20/18722 0.286351846878687 0.477294869118723 ANXA1 1 GO:0045844 positive regulation of striated muscle tissue development 1/313 20/18722 0.286351846878687 0.477294869118723 IGF2 1 GO:0046629 gamma-delta T cell activation 1/313 20/18722 0.286351846878687 0.477294869118723 SOX4 1 GO:0048636 positive regulation of muscle organ development 1/313 20/18722 0.286351846878687 0.477294869118723 IGF2 1 GO:0051900 regulation of mitochondrial depolarization 1/313 20/18722 0.286351846878687 0.477294869118723 PARP1 1 GO:0060044 negative regulation of cardiac muscle cell proliferation 1/313 20/18722 0.286351846878687 0.477294869118723 GJA1 1 GO:0071243 cellular response to arsenic-containing substance 1/313 20/18722 0.286351846878687 0.477294869118723 GSTO1 1 GO:0097150 neuronal stem cell population maintenance 1/313 20/18722 0.286351846878687 0.477294869118723 HES1 1 GO:1901386 negative regulation of voltage-gated calcium channel activity 1/313 20/18722 0.286351846878687 0.477294869118723 CALM1 1 GO:1902004 positive regulation of amyloid-beta formation 1/313 20/18722 0.286351846878687 0.477294869118723 CLU 1 GO:1903817 negative regulation of voltage-gated potassium channel activity 1/313 20/18722 0.286351846878687 0.477294869118723 CAV1 1 GO:0016049 cell growth 10/313 482/18722 0.288036853257202 0.479710732509401 FN1/NRP2/ENO1/SEMA6D/RHOA/ITGB1/HSPA1A/GJA1/EPB41L3/RGS2 10 GO:0000956 nuclear-transcribed mRNA catabolic process 3/313 112/18722 0.288431275732603 0.479710732509401 DDX5/SSB/BTG2 3 GO:0032609 interferon-gamma production 3/313 112/18722 0.288431275732603 0.479710732509401 SLC7A5/ISL1/PDE4B 3 GO:0032649 regulation of interferon-gamma production 3/313 112/18722 0.288431275732603 0.479710732509401 SLC7A5/ISL1/PDE4B 3 GO:1901222 regulation of NIK/NF-kappaB signaling 3/313 112/18722 0.288431275732603 0.479710732509401 PRDX1/RHOA/TMSB4X 3 GO:0009895 negative regulation of catabolic process 7/313 320/18722 0.288793876484797 0.480104055798088 RPL23/TIMP2/TIMP3/YBX3/FUS/PKP3/YBX1 7 GO:0016126 sterol biosynthetic process 2/313 64/18722 0.290204502218512 0.48160790756141 DHCR24/CYB5R1 2 GO:0017156 calcium-ion regulated exocytosis 2/313 64/18722 0.290204502218512 0.48160790756141 MYH9/SCIN 2 GO:1900076 regulation of cellular response to insulin stimulus 2/313 64/18722 0.290204502218512 0.48160790756141 IGF2/ATP2B1 2 GO:1903409 reactive oxygen species biosynthetic process 2/313 64/18722 0.290204502218512 0.48160790756141 PAGE4/RHOA 2 GO:0061025 membrane fusion 4/313 163/18722 0.290638937160923 0.482118707525766 ANXA1/CAV2/SPESP1/CLN3 4 GO:0031669 cellular response to nutrient levels 5/313 215/18722 0.291363480027907 0.483110090795401 PMAIP1/ATP2B1/JUN/STK24/SLC2A1 5 GO:0150063 visual system development 8/313 375/18722 0.291874944389283 0.483747458985633 RDH13/FBN1/ATP2B1/CLIC4/C12orf57/FKBP8/FLT1/MFAP5 8 GO:0043010 camera-type eye development 7/313 322/18722 0.294051287130566 0.484889542571289 RDH13/FBN1/ATP2B1/CLIC4/C12orf57/FKBP8/FLT1 7 GO:0003170 heart valve development 2/313 65/18722 0.296399836129525 0.484889542571289 TNFRSF1A/SOX4 2 GO:0044784 metaphase/anaphase transition of cell cycle 2/313 65/18722 0.296399836129525 0.484889542571289 NEK6/CCNB1 2 GO:0045682 regulation of epidermis development 2/313 65/18722 0.296399836129525 0.484889542571289 ERRFI1/HES1 2 GO:0046513 ceramide biosynthetic process 2/313 65/18722 0.296399836129525 0.484889542571289 ORMDL1/SPTSSA 2 GO:0048645 animal organ formation 2/313 65/18722 0.296399836129525 0.484889542571289 ISL1/HES1 2 GO:1905330 regulation of morphogenesis of an epithelium 2/313 65/18722 0.296399836129525 0.484889542571289 MAGED1/GJA1 2 GO:1904892 regulation of receptor signaling pathway via STAT 3/313 114/18722 0.297553958684171 0.484889542571289 CAV1/AKR1B1/HES1 3 GO:0000002 mitochondrial genome maintenance 1/313 21/18722 0.298295589362216 0.484889542571289 PARP1 1 GO:0002689 negative regulation of leukocyte chemotaxis 1/313 21/18722 0.298295589362216 0.484889542571289 MIF 1 GO:0003091 renal water homeostasis 1/313 21/18722 0.298295589362216 0.484889542571289 AKR1B1 1 GO:0003177 pulmonary valve development 1/313 21/18722 0.298295589362216 0.484889542571289 TNFRSF1A 1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen 1/313 21/18722 0.298295589362216 0.484889542571289 COX4I1 1 GO:0006925 inflammatory cell apoptotic process 1/313 21/18722 0.298295589362216 0.484889542571289 ANXA1 1 GO:0007350 blastoderm segmentation 1/313 21/18722 0.298295589362216 0.484889542571289 NRP2 1 GO:0008090 retrograde axonal transport 1/313 21/18722 0.298295589362216 0.484889542571289 DST 1 GO:0009070 serine family amino acid biosynthetic process 1/313 21/18722 0.298295589362216 0.484889542571289 SERINC5 1 GO:0022010 central nervous system myelination 1/313 21/18722 0.298295589362216 0.484889542571289 CLU 1 GO:0023019 signal transduction involved in regulation of gene expression 1/313 21/18722 0.298295589362216 0.484889542571289 PARP1 1 GO:0031145 anaphase-promoting complex-dependent catabolic process 1/313 21/18722 0.298295589362216 0.484889542571289 CDC20 1 GO:0032288 myelin assembly 1/313 21/18722 0.298295589362216 0.484889542571289 EPB41L3 1 GO:0032291 axon ensheathment in central nervous system 1/313 21/18722 0.298295589362216 0.484889542571289 CLU 1 GO:0033630 positive regulation of cell adhesion mediated by integrin 1/313 21/18722 0.298295589362216 0.484889542571289 FERMT1 1 GO:0034035 purine ribonucleoside bisphosphate metabolic process 1/313 21/18722 0.298295589362216 0.484889542571289 SLC26A2 1 GO:0034471 ncRNA 5'-end processing 1/313 21/18722 0.298295589362216 0.484889542571289 SSB 1 GO:0035020 regulation of Rac protein signal transduction 1/313 21/18722 0.298295589362216 0.484889542571289 STMN3 1 GO:0038083 peptidyl-tyrosine autophosphorylation 1/313 21/18722 0.298295589362216 0.484889542571289 CAV1 1 GO:0045056 transcytosis 1/313 21/18722 0.298295589362216 0.484889542571289 RAB17 1 GO:0045655 regulation of monocyte differentiation 1/313 21/18722 0.298295589362216 0.484889542571289 JUN 1 GO:0046597 negative regulation of viral entry into host cell 1/313 21/18722 0.298295589362216 0.484889542571289 LY6E 1 GO:0046599 regulation of centriole replication 1/313 21/18722 0.298295589362216 0.484889542571289 PLK2 1 GO:0046823 negative regulation of nucleocytoplasmic transport 1/313 21/18722 0.298295589362216 0.484889542571289 FERMT1 1 GO:0048199 vesicle targeting, to, from or within Golgi 1/313 21/18722 0.298295589362216 0.484889542571289 PDCD6 1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process 1/313 21/18722 0.298295589362216 0.484889542571289 SLC26A2 1 GO:0050849 negative regulation of calcium-mediated signaling 1/313 21/18722 0.298295589362216 0.484889542571289 FHL2 1 GO:0071498 cellular response to fluid shear stress 1/313 21/18722 0.298295589362216 0.484889542571289 TFPI2 1 GO:0072111 cell proliferation involved in kidney development 1/313 21/18722 0.298295589362216 0.484889542571289 EGR1 1 GO:0072170 metanephric tubule development 1/313 21/18722 0.298295589362216 0.484889542571289 HES1 1 GO:0072243 metanephric nephron epithelium development 1/313 21/18722 0.298295589362216 0.484889542571289 HES1 1 GO:0090189 regulation of branching involved in ureteric bud morphogenesis 1/313 21/18722 0.298295589362216 0.484889542571289 MAGED1 1 GO:0097062 dendritic spine maintenance 1/313 21/18722 0.298295589362216 0.484889542571289 INSR 1 GO:1901863 positive regulation of muscle tissue development 1/313 21/18722 0.298295589362216 0.484889542571289 IGF2 1 GO:2000178 negative regulation of neural precursor cell proliferation 1/313 21/18722 0.298295589362216 0.484889542571289 BTG2 1 GO:2000291 regulation of myoblast proliferation 1/313 21/18722 0.298295589362216 0.484889542571289 MALAT1 1 GO:2001014 regulation of skeletal muscle cell differentiation 1/313 21/18722 0.298295589362216 0.484889542571289 DDX5 1 GO:0000077 DNA damage checkpoint signaling 3/313 115/18722 0.302121822764504 0.490191079865682 SOX4/PPP1R10/PLK2 3 GO:0046916 cellular transition metal ion homeostasis 3/313 115/18722 0.302121822764504 0.490191079865682 FTL/FTH1/SRI 3 GO:0071675 regulation of mononuclear cell migration 3/313 115/18722 0.302121822764504 0.490191079865682 SERPINE1/RHOA/LGMN 3 GO:0014015 positive regulation of gliogenesis 2/313 66/18722 0.302587086336841 0.490191079865682 ID2/HES1 2 GO:0030193 regulation of blood coagulation 2/313 66/18722 0.302587086336841 0.490191079865682 CAV1/SERPINE1 2 GO:0050922 negative regulation of chemotaxis 2/313 66/18722 0.302587086336841 0.490191079865682 MIF/SEMA6D 2 GO:0072678 T cell migration 2/313 66/18722 0.302587086336841 0.490191079865682 CD99/RHOA 2 GO:2000272 negative regulation of signaling receptor activity 2/313 66/18722 0.302587086336841 0.490191079865682 LY6E/ERRFI1 2 GO:0031123 RNA 3'-end processing 3/313 116/18722 0.306693084623778 0.495101734869623 RPS21/SSB/CCNB1 3 GO:0034249 negative regulation of cellular amide metabolic process 6/313 273/18722 0.30683587576413 0.495101734869623 GAPDH/ORMDL1/YBX1/BTG2/CLU/RGS2 6 GO:0009880 embryonic pattern specification 2/313 67/18722 0.308764795247574 0.495101734869623 EFNB1/NRP2 2 GO:0042490 mechanoreceptor differentiation 2/313 67/18722 0.308764795247574 0.495101734869623 MCOLN3/HES1 2 GO:0046635 positive regulation of alpha-beta T cell activation 2/313 67/18722 0.308764795247574 0.495101734869623 ANXA1/RHOA 2 GO:0000070 mitotic sister chromatid segregation 4/313 168/18722 0.309414428769347 0.495101734869623 NEK6/PTTG1/CDC20/CCNB1 4 GO:2000241 regulation of reproductive process 4/313 168/18722 0.309414428769347 0.495101734869623 PHLDA2/MYH9/CDC20/GJA1 4 GO:0006359 regulation of transcription by RNA polymerase III 1/313 22/18722 0.310040067225947 0.495101734869623 ICE1 1 GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization 1/313 22/18722 0.310040067225947 0.495101734869623 SPESP1 1 GO:0008211 glucocorticoid metabolic process 1/313 22/18722 0.310040067225947 0.495101734869623 CYP11A1 1 GO:0016137 glycoside metabolic process 1/313 22/18722 0.310040067225947 0.495101734869623 AKR1B1 1 GO:0021854 hypothalamus development 1/313 22/18722 0.310040067225947 0.495101734869623 NRP2 1 GO:0021904 dorsal/ventral neural tube patterning 1/313 22/18722 0.310040067225947 0.495101734869623 FKBP8 1 GO:0031281 positive regulation of cyclase activity 1/313 22/18722 0.310040067225947 0.495101734869623 TIMP2 1 GO:0032402 melanosome transport 1/313 22/18722 0.310040067225947 0.495101734869623 RAB17 1 GO:0034629 cellular protein-containing complex localization 1/313 22/18722 0.310040067225947 0.495101734869623 EZR 1 GO:0035089 establishment of apical/basal cell polarity 1/313 22/18722 0.310040067225947 0.495101734869623 RHOA 1 GO:0035809 regulation of urine volume 1/313 22/18722 0.310040067225947 0.495101734869623 AKR1B1 1 GO:0036120 cellular response to platelet-derived growth factor stimulus 1/313 22/18722 0.310040067225947 0.495101734869623 ERRFI1 1 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation 1/313 22/18722 0.310040067225947 0.495101734869623 ANXA1 1 GO:0044346 fibroblast apoptotic process 1/313 22/18722 0.310040067225947 0.495101734869623 STK17A 1 GO:0045624 positive regulation of T-helper cell differentiation 1/313 22/18722 0.310040067225947 0.495101734869623 ANXA1 1 GO:0045663 positive regulation of myoblast differentiation 1/313 22/18722 0.310040067225947 0.495101734869623 IGFBP3 1 GO:0046058 cAMP metabolic process 1/313 22/18722 0.310040067225947 0.495101734869623 PDE4B 1 GO:0046628 positive regulation of insulin receptor signaling pathway 1/313 22/18722 0.310040067225947 0.495101734869623 IGF2 1 GO:0055093 response to hyperoxia 1/313 22/18722 0.310040067225947 0.495101734869623 CAV1 1 GO:0061042 vascular wound healing 1/313 22/18722 0.310040067225947 0.495101734869623 SERPINE1 1 GO:0071359 cellular response to dsRNA 1/313 22/18722 0.310040067225947 0.495101734869623 CAV1 1 GO:0071404 cellular response to low-density lipoprotein particle stimulus 1/313 22/18722 0.310040067225947 0.495101734869623 ITGB1 1 GO:0072574 hepatocyte proliferation 1/313 22/18722 0.310040067225947 0.495101734869623 CEBPB 1 GO:0072575 epithelial cell proliferation involved in liver morphogenesis 1/313 22/18722 0.310040067225947 0.495101734869623 CEBPB 1 GO:0140467 integrated stress response signaling 1/313 22/18722 0.310040067225947 0.495101734869623 PPP1R15A 1 GO:1900120 regulation of receptor binding 1/313 22/18722 0.310040067225947 0.495101734869623 PHLDA2 1 GO:1900543 negative regulation of purine nucleotide metabolic process 1/313 22/18722 0.310040067225947 0.495101734869623 PARP1 1 GO:0008406 gonad development 5/313 221/18722 0.310887293357444 0.496246509774336 CYP19A1/YBX3/IDH1/CEBPB/ADAMTS1 5 GO:1903828 negative regulation of cellular protein localization 3/313 117/18722 0.311267044735383 0.496644442291535 MAGED1/TMBIM1/FERMT1 3 GO:0000075 cell cycle checkpoint signaling 4/313 169/18722 0.313185005262314 0.499286145323965 SOX4/PPP1R10/PLK2/CCNB1 4 GO:0018394 peptidyl-lysine acetylation 4/313 169/18722 0.313185005262314 0.499286145323965 MBD3/ISL1/SOX4/MORF4L2 4 GO:0022412 cellular process involved in reproduction in multicellular organism 8/313 384/18722 0.313924244285528 0.50018541239333 DYNLL1/ITGB1/SPESP1/LGR5/JAM3/TOP2A/DNMT3A/CCNB1 8 GO:0031640 killing of cells of other organism 2/313 68/18722 0.314931555951356 0.50018541239333 GAPDH/SERPINB9 2 GO:0042267 natural killer cell mediated cytotoxicity 2/313 68/18722 0.314931555951356 0.50018541239333 SERPINB9/PRDX1 2 GO:0042698 ovulation cycle 2/313 68/18722 0.314931555951356 0.50018541239333 EGR1/ADAMTS1 2 GO:0046637 regulation of alpha-beta T cell differentiation 2/313 68/18722 0.314931555951356 0.50018541239333 ANXA1/RHOA 2 GO:0046686 response to cadmium ion 2/313 68/18722 0.314931555951356 0.50018541239333 FOS/JUN 2 GO:1900046 regulation of hemostasis 2/313 68/18722 0.314931555951356 0.50018541239333 CAV1/SERPINE1 2 GO:1901016 regulation of potassium ion transmembrane transporter activity 2/313 68/18722 0.314931555951356 0.50018541239333 CAV1/ITGB1 2 GO:1901607 alpha-amino acid biosynthetic process 2/313 68/18722 0.314931555951356 0.50018541239333 SERINC5/CLN3 2 GO:0007548 sex differentiation 6/313 276/18722 0.315606731428753 0.500321936675267 CYP19A1/YBX3/IDH1/DHCR24/CEBPB/ADAMTS1 6 GO:1903829 positive regulation of cellular protein localization 6/313 276/18722 0.315606731428753 0.500321936675267 TCAF1/EZR/ITGB1/PARP1/CLN3/NMT1 6 GO:0071346 cellular response to interferon-gamma 3/313 118/18722 0.315843014368741 0.500321936675267 GAPDH/FLNB/ACTG1 3 GO:0043487 regulation of RNA stability 4/313 170/18722 0.316959790876132 0.500321936675267 YBX3/FUS/YBX1/BTG2 4 GO:0002274 myeloid leukocyte activation 5/313 223/18722 0.317436769295826 0.500321936675267 DHRS2/MIF/CTSC/ITGB8/CLU 5 GO:0019216 regulation of lipid metabolic process 7/313 331/18722 0.317958573158161 0.500321936675267 CAV1/ANXA1/IDH1/ORMDL1/FLT1/EGR1/ID2 7 GO:0046890 regulation of lipid biosynthetic process 4/313 171/18722 0.320738385166204 0.500321936675267 ANXA1/IDH1/ORMDL1/EGR1 4 GO:0034605 cellular response to heat 2/313 69/18722 0.321086010942471 0.500321936675267 PDCD6/HSPA1A 2 GO:0045669 positive regulation of osteoblast differentiation 2/313 69/18722 0.321086010942471 0.500321936675267 CLIC1/CEBPB 2 GO:0060193 positive regulation of lipase activity 2/313 69/18722 0.321086010942471 0.500321936675267 RHOA/FLT1 2 GO:0031349 positive regulation of defense response 6/313 278/18722 0.32147625101588 0.500321936675267 NEAT1/TNFRSF1A/SERPINE1/CTSC/CEBPB/GJA1 6 GO:0000966 RNA 5'-end processing 1/313 23/18722 0.321588594442968 0.500321936675267 SSB 1 GO:0002082 regulation of oxidative phosphorylation 1/313 23/18722 0.321588594442968 0.500321936675267 RHOA 1 GO:0002363 alpha-beta T cell lineage commitment 1/313 23/18722 0.321588594442968 0.500321936675267 RHOA 1 GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 1/313 23/18722 0.321588594442968 0.500321936675267 RHOA 1 GO:0006622 protein targeting to lysosome 1/313 23/18722 0.321588594442968 0.500321936675267 CLU 1 GO:0006929 substrate-dependent cell migration 1/313 23/18722 0.321588594442968 0.500321936675267 FN1 1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules 1/313 23/18722 0.321588594442968 0.500321936675267 CLDN7 1 GO:0021871 forebrain regionalization 1/313 23/18722 0.321588594442968 0.500321936675267 TRA2B 1 GO:0021884 forebrain neuron development 1/313 23/18722 0.321588594442968 0.500321936675267 NRP2 1 GO:0030194 positive regulation of blood coagulation 1/313 23/18722 0.321588594442968 0.500321936675267 SERPINE1 1 GO:0030325 adrenal gland development 1/313 23/18722 0.321588594442968 0.500321936675267 LY6E 1 GO:0030539 male genitalia development 1/313 23/18722 0.321588594442968 0.500321936675267 DHCR24 1 GO:0031338 regulation of vesicle fusion 1/313 23/18722 0.321588594442968 0.500321936675267 ANXA1 1 GO:0032401 establishment of melanosome localization 1/313 23/18722 0.321588594442968 0.500321936675267 RAB17 1 GO:0032740 positive regulation of interleukin-17 production 1/313 23/18722 0.321588594442968 0.500321936675267 SLC7A5 1 GO:0034105 positive regulation of tissue remodeling 1/313 23/18722 0.321588594442968 0.500321936675267 TMBIM1 1 GO:0034695 response to prostaglandin E 1/313 23/18722 0.321588594442968 0.500321936675267 TGFBR3 1 GO:0035994 response to muscle stretch 1/313 23/18722 0.321588594442968 0.500321936675267 FOS 1 GO:0036119 response to platelet-derived growth factor 1/313 23/18722 0.321588594442968 0.500321936675267 ERRFI1 1 GO:0036303 lymph vessel morphogenesis 1/313 23/18722 0.321588594442968 0.500321936675267 SVEP1 1 GO:0040019 positive regulation of embryonic development 1/313 23/18722 0.321588594442968 0.500321936675267 CFL1 1 GO:0042026 protein refolding 1/313 23/18722 0.321588594442968 0.500321936675267 HSPA1A 1 GO:0043931 ossification involved in bone maturation 1/313 23/18722 0.321588594442968 0.500321936675267 RHOA 1 GO:0045723 positive regulation of fatty acid biosynthetic process 1/313 23/18722 0.321588594442968 0.500321936675267 ANXA1 1 GO:0045980 negative regulation of nucleotide metabolic process 1/313 23/18722 0.321588594442968 0.500321936675267 PARP1 1 GO:0051349 positive regulation of lyase activity 1/313 23/18722 0.321588594442968 0.500321936675267 TIMP2 1 GO:0051590 positive regulation of neurotransmitter transport 1/313 23/18722 0.321588594442968 0.500321936675267 ITGB1 1 GO:0051882 mitochondrial depolarization 1/313 23/18722 0.321588594442968 0.500321936675267 PARP1 1 GO:0051904 pigment granule transport 1/313 23/18722 0.321588594442968 0.500321936675267 RAB17 1 GO:0060353 regulation of cell adhesion molecule production 1/313 23/18722 0.321588594442968 0.500321936675267 CAV1 1 GO:0060384 innervation 1/313 23/18722 0.321588594442968 0.500321936675267 ISL1 1 GO:0061050 regulation of cell growth involved in cardiac muscle cell development 1/313 23/18722 0.321588594442968 0.500321936675267 RGS2 1 GO:0071305 cellular response to vitamin D 1/313 23/18722 0.321588594442968 0.500321936675267 ATP2B1 1 GO:0071636 positive regulation of transforming growth factor beta production 1/313 23/18722 0.321588594442968 0.500321936675267 FERMT1 1 GO:0072576 liver morphogenesis 1/313 23/18722 0.321588594442968 0.500321936675267 CEBPB 1 GO:1900048 positive regulation of hemostasis 1/313 23/18722 0.321588594442968 0.500321936675267 SERPINE1 1 GO:1900273 positive regulation of long-term synaptic potentiation 1/313 23/18722 0.321588594442968 0.500321936675267 LGMN 1 GO:1902410 mitotic cytokinetic process 1/313 23/18722 0.321588594442968 0.500321936675267 RHOA 1 GO:2000810 regulation of bicellular tight junction assembly 1/313 23/18722 0.321588594442968 0.500321936675267 GJA1 1 GO:0010001 glial cell differentiation 5/313 225/18722 0.324003433788886 0.50387298710551 SOX4/RHOA/CLU/ID2/HES1 5 GO:1990138 neuron projection extension 4/313 172/18722 0.324520391210594 0.504470857222839 FN1/NRP2/SEMA6D/ITGB1 4 GO:0003407 neural retina development 2/313 70/18722 0.327226850870321 0.508263003371405 RDH13/ATP2B1 2 GO:0070830 bicellular tight junction assembly 2/313 70/18722 0.327226850870321 0.508263003371405 GJA1/CLDN7 2 GO:1901987 regulation of cell cycle phase transition 8/313 390/18722 0.328809590830523 0.510513096366966 NEK6/ANXA1/SOX4/PPP1R10/ADAMTS1/PLK2/ID2/CCNB1 8 GO:0042177 negative regulation of protein catabolic process 3/313 121/18722 0.329576255554389 0.51069382708262 RPL23/TIMP2/TIMP3 3 GO:0042752 regulation of circadian rhythm 3/313 121/18722 0.329576255554389 0.51069382708262 MAGED1/ID2/TOP2A 3 GO:0045137 development of primary sexual characteristics 5/313 227/18722 0.330585170507353 0.51069382708262 CYP19A1/YBX3/IDH1/CEBPB/ADAMTS1 5 GO:0045619 regulation of lymphocyte differentiation 4/313 174/18722 0.332093068843017 0.51069382708262 ANXA1/SOX4/RHOA/ID2 4 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/313 24/18722 0.332944430045906 0.51069382708262 RPS21 1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity 1/313 24/18722 0.332944430045906 0.51069382708262 SERPINB9 1 GO:0003181 atrioventricular valve morphogenesis 1/313 24/18722 0.332944430045906 0.51069382708262 SOX4 1 GO:0006817 phosphate ion transport 1/313 24/18722 0.332944430045906 0.51069382708262 CEBPB 1 GO:0010155 regulation of proton transport 1/313 24/18722 0.332944430045906 0.51069382708262 TMSB4X 1 GO:0010288 response to lead ion 1/313 24/18722 0.332944430045906 0.51069382708262 DNMT3A 1 GO:0030859 polarized epithelial cell differentiation 1/313 24/18722 0.332944430045906 0.51069382708262 RHOA 1 GO:0032528 microvillus organization 1/313 24/18722 0.332944430045906 0.51069382708262 EZR 1 GO:0033032 regulation of myeloid cell apoptotic process 1/313 24/18722 0.332944430045906 0.51069382708262 ANXA1 1 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress 1/313 24/18722 0.332944430045906 0.51069382708262 CEBPB 1 GO:0036010 protein localization to endosome 1/313 24/18722 0.332944430045906 0.51069382708262 EZR 1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 1/313 24/18722 0.332944430045906 0.51069382708262 IGFBP3 1 GO:0045649 regulation of macrophage differentiation 1/313 24/18722 0.332944430045906 0.51069382708262 ID2 1 GO:0050687 negative regulation of defense response to virus 1/313 24/18722 0.332944430045906 0.51069382708262 HTRA1 1 GO:0050820 positive regulation of coagulation 1/313 24/18722 0.332944430045906 0.51069382708262 SERPINE1 1 GO:0051000 positive regulation of nitric-oxide synthase activity 1/313 24/18722 0.332944430045906 0.51069382708262 CALM1 1 GO:0051156 glucose 6-phosphate metabolic process 1/313 24/18722 0.332944430045906 0.51069382708262 PGAM1 1 GO:0051905 establishment of pigment granule localization 1/313 24/18722 0.332944430045906 0.51069382708262 RAB17 1 GO:0060561 apoptotic process involved in morphogenesis 1/313 24/18722 0.332944430045906 0.51069382708262 TNFRSF1A 1 GO:0061162 establishment of monopolar cell polarity 1/313 24/18722 0.332944430045906 0.51069382708262 RHOA 1 GO:0070935 3'-UTR-mediated mRNA stabilization 1/313 24/18722 0.332944430045906 0.51069382708262 YBX3 1 GO:0071294 cellular response to zinc ion 1/313 24/18722 0.332944430045906 0.51069382708262 PARP1 1 GO:1903077 negative regulation of protein localization to plasma membrane 1/313 24/18722 0.332944430045906 0.51069382708262 TMBIM1 1 GO:2000679 positive regulation of transcription regulatory region DNA binding 1/313 24/18722 0.332944430045906 0.51069382708262 PARP1 1 GO:0002228 natural killer cell mediated immunity 2/313 71/18722 0.333352813317655 0.51069382708262 SERPINB9/PRDX1 2 GO:0050795 regulation of behavior 2/313 71/18722 0.333352813317655 0.51069382708262 GJA1/ARRDC3 2 GO:0050818 regulation of coagulation 2/313 71/18722 0.333352813317655 0.51069382708262 CAV1/SERPINE1 2 GO:0071230 cellular response to amino acid stimulus 2/313 71/18722 0.333352813317655 0.51069382708262 CEBPB/DNMT3A 2 GO:0072078 nephron tubule morphogenesis 2/313 71/18722 0.333352813317655 0.51069382708262 MAGED1/HES1 2 GO:0046486 glycerolipid metabolic process 8/313 392/18722 0.33379919176827 0.51117197226943 CAV1/GPX1/ABHD8/DBI/SERINC5/CLN3/PRDX6/PGP 8 GO:0033157 regulation of intracellular protein transport 5/313 229/18722 0.337179886419888 0.515934014308889 TCAF1/ICE1/OAZ1/NMT1/FERMT1 5 GO:0071695 anatomical structure maturation 5/313 229/18722 0.337179886419888 0.515934014308889 RHOA/AKR1B1/FERMT1/CCNB1/HES1 5 GO:0031570 DNA integrity checkpoint signaling 3/313 123/18722 0.33872965834821 0.517889080052865 SOX4/PPP1R10/PLK2 3 GO:0050852 T cell receptor signaling pathway 3/313 123/18722 0.33872965834821 0.517889080052865 PHPT1/EZR/PDE4B 3 GO:0015850 organic hydroxy compound transport 6/313 284/18722 0.339174962099808 0.518361734529895 CAV1/LY6E/CYP19A1/SLC16A1/ACTB/CLU 6 GO:0071479 cellular response to ionizing radiation 2/313 72/18722 0.339462681605966 0.518593270013609 EGR1/RHOB 2 GO:0050728 negative regulation of inflammatory response 4/313 176/18722 0.339674721049645 0.518618264364904 GPX1/TNFRSF1A/ISL1/PLK2 4 GO:0001909 leukocyte mediated cytotoxicity 3/313 124/18722 0.343303828899213 0.518618264364904 SERPINB9/PRDX1/CTSC 3 GO:0003094 glomerular filtration 1/313 25/18722 0.344110779034869 0.518618264364904 GJA1 1 GO:0006658 phosphatidylserine metabolic process 1/313 25/18722 0.344110779034869 0.518618264364904 SERINC5 1 GO:0010447 response to acidic pH 1/313 25/18722 0.344110779034869 0.518618264364904 LGMN 1 GO:0010842 retina layer formation 1/313 25/18722 0.344110779034869 0.518618264364904 RDH13 1 GO:0015012 heparan sulfate proteoglycan biosynthetic process 1/313 25/18722 0.344110779034869 0.518618264364904 EXTL2 1 GO:0015874 norepinephrine transport 1/313 25/18722 0.344110779034869 0.518618264364904 ACTB 1 GO:0016540 protein autoprocessing 1/313 25/18722 0.344110779034869 0.518618264364904 PARP1 1 GO:0032400 melanosome localization 1/313 25/18722 0.344110779034869 0.518618264364904 RAB17 1 GO:0033119 negative regulation of RNA splicing 1/313 25/18722 0.344110779034869 0.518618264364904 TMBIM6 1 GO:0035336 long-chain fatty-acyl-CoA metabolic process 1/313 25/18722 0.344110779034869 0.518618264364904 TECR 1 GO:0035902 response to immobilization stress 1/313 25/18722 0.344110779034869 0.518618264364904 FOS 1 GO:0042730 fibrinolysis 1/313 25/18722 0.344110779034869 0.518618264364904 SERPINE1 1 GO:0045109 intermediate filament organization 1/313 25/18722 0.344110779034869 0.518618264364904 DSP 1 GO:0045822 negative regulation of heart contraction 1/313 25/18722 0.344110779034869 0.518618264364904 SRI 1 GO:0046039 GTP metabolic process 1/313 25/18722 0.344110779034869 0.518618264364904 RHOA 1 GO:0046949 fatty-acyl-CoA biosynthetic process 1/313 25/18722 0.344110779034869 0.518618264364904 TECR 1 GO:0051204 protein insertion into mitochondrial membrane 1/313 25/18722 0.344110779034869 0.518618264364904 NMT1 1 GO:0051307 meiotic chromosome separation 1/313 25/18722 0.344110779034869 0.518618264364904 TOP2A 1 GO:0051788 response to misfolded protein 1/313 25/18722 0.344110779034869 0.518618264364904 CLU 1 GO:0061339 establishment or maintenance of monopolar cell polarity 1/313 25/18722 0.344110779034869 0.518618264364904 RHOA 1 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 1/313 25/18722 0.344110779034869 0.518618264364904 HSPA1A 1 GO:0072207 metanephric epithelium development 1/313 25/18722 0.344110779034869 0.518618264364904 HES1 1 GO:0090382 phagosome maturation 1/313 25/18722 0.344110779034869 0.518618264364904 CLN3 1 GO:1900078 positive regulation of cellular response to insulin stimulus 1/313 25/18722 0.344110779034869 0.518618264364904 IGF2 1 GO:1902993 positive regulation of amyloid precursor protein catabolic process 1/313 25/18722 0.344110779034869 0.518618264364904 CLU 1 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA 1/313 25/18722 0.344110779034869 0.518618264364904 DDX5 1 GO:1903901 negative regulation of viral life cycle 1/313 25/18722 0.344110779034869 0.518618264364904 LY6E 1 GO:1904385 cellular response to angiotensin 1/313 25/18722 0.344110779034869 0.518618264364904 CAV1 1 GO:1904754 positive regulation of vascular associated smooth muscle cell migration 1/313 25/18722 0.344110779034869 0.518618264364904 ADAMTS1 1 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell 1/313 25/18722 0.344110779034869 0.518618264364904 RHOA 1 GO:1905563 negative regulation of vascular endothelial cell proliferation 1/313 25/18722 0.344110779034869 0.518618264364904 FLT1 1 GO:1905564 positive regulation of vascular endothelial cell proliferation 1/313 25/18722 0.344110779034869 0.518618264364904 IGF2 1 GO:0045739 positive regulation of DNA repair 2/313 73/18722 0.345555283627514 0.519971922833971 FUS/PARP1 2 GO:0050848 regulation of calcium-mediated signaling 2/313 73/18722 0.345555283627514 0.519971922833971 FHL2/CALM1 2 GO:0051937 catecholamine transport 2/313 73/18722 0.345555283627514 0.519971922833971 LY6E/ACTB 2 GO:0072088 nephron epithelium morphogenesis 2/313 73/18722 0.345555283627514 0.519971922833971 MAGED1/HES1 2 GO:0032496 response to lipopolysaccharide 7/313 343/18722 0.350327723576121 0.524575339534532 FOS/JUN/SERPINE1/RHOA/CEBPB/PDE4B/GJA1 7 GO:0007626 locomotory behavior 4/313 179/18722 0.351057387267387 0.524575339534532 ARRDC3/EGR1/MCOLN3/ID2 4 GO:0010950 positive regulation of endopeptidase activity 4/313 179/18722 0.351057387267387 0.524575339534532 PMAIP1/PDCD6/RHOA/LGMN 4 GO:0002437 inflammatory response to antigenic stimulus 2/313 74/18722 0.351629490703403 0.524575339534532 GPX1/PLK2 2 GO:0006635 fatty acid beta-oxidation 2/313 74/18722 0.351629490703403 0.524575339534532 CROT/SLC27A2 2 GO:0006801 superoxide metabolic process 2/313 74/18722 0.351629490703403 0.524575339534532 PRDX1/SOD3 2 GO:0010822 positive regulation of mitochondrion organization 2/313 74/18722 0.351629490703403 0.524575339534532 PMAIP1/NMT1 2 GO:0030968 endoplasmic reticulum unfolded protein response 2/313 74/18722 0.351629490703403 0.524575339534532 HERPUD1/PPP1R15A 2 GO:0046323 glucose import 2/313 74/18722 0.351629490703403 0.524575339534532 INSR/SLC2A1 2 GO:0048844 artery morphogenesis 2/313 74/18722 0.351629490703403 0.524575339534532 SOX4/HES1 2 GO:0032874 positive regulation of stress-activated MAPK cascade 3/313 126/18722 0.352444044418593 0.524575339534532 GADD45B/PRMT1/MAP3K4 3 GO:0048588 developmental cell growth 5/313 234/18722 0.353709950067223 0.524575339534532 FN1/NRP2/SEMA6D/ITGB1/RGS2 5 GO:0010721 negative regulation of cell development 4/313 180/18722 0.354852839318559 0.524575339534532 FBN1/SEMA6D/FBLN1/HES1 4 GO:0001556 oocyte maturation 1/313 26/18722 0.35509079327042 0.524575339534532 CCNB1 1 GO:0001573 ganglioside metabolic process 1/313 26/18722 0.35509079327042 0.524575339534532 ITGB8 1 GO:0002026 regulation of the force of heart contraction 1/313 26/18722 0.35509079327042 0.524575339534532 CAV1 1 GO:0006706 steroid catabolic process 1/313 26/18722 0.35509079327042 0.524575339534532 CYP19A1 1 GO:0010875 positive regulation of cholesterol efflux 1/313 26/18722 0.35509079327042 0.524575339534532 CAV1 1 GO:0021952 central nervous system projection neuron axonogenesis 1/313 26/18722 0.35509079327042 0.524575339534532 C12orf57 1 GO:0032515 negative regulation of phosphoprotein phosphatase activity 1/313 26/18722 0.35509079327042 0.524575339534532 PPP1R15A 1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated 1/313 26/18722 0.35509079327042 0.524575339534532 ARMCX3 1 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 1/313 26/18722 0.35509079327042 0.524575339534532 HSPA1A 1 GO:0042634 regulation of hair cycle 1/313 26/18722 0.35509079327042 0.524575339534532 FERMT1 1 GO:0045026 plasma membrane fusion 1/313 26/18722 0.35509079327042 0.524575339534532 SPESP1 1 GO:0045672 positive regulation of osteoclast differentiation 1/313 26/18722 0.35509079327042 0.524575339534532 FOS 1 GO:0046639 negative regulation of alpha-beta T cell differentiation 1/313 26/18722 0.35509079327042 0.524575339534532 ANXA1 1 GO:0047497 mitochondrion transport along microtubule 1/313 26/18722 0.35509079327042 0.524575339534532 ARMCX3 1 GO:0048843 negative regulation of axon extension involved in axon guidance 1/313 26/18722 0.35509079327042 0.524575339534532 SEMA6D 1 GO:0051016 barbed-end actin filament capping 1/313 26/18722 0.35509079327042 0.524575339534532 SCIN 1 GO:0051350 negative regulation of lyase activity 1/313 26/18722 0.35509079327042 0.524575339534532 PHPT1 1 GO:0051875 pigment granule localization 1/313 26/18722 0.35509079327042 0.524575339534532 RAB17 1 GO:0060295 regulation of cilium movement involved in cell motility 1/313 26/18722 0.35509079327042 0.524575339534532 CCSAP 1 GO:0060352 cell adhesion molecule production 1/313 26/18722 0.35509079327042 0.524575339534532 CAV1 1 GO:0060669 embryonic placenta morphogenesis 1/313 26/18722 0.35509079327042 0.524575339534532 IGF2 1 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA 1/313 26/18722 0.35509079327042 0.524575339534532 DDX5 1 GO:0070977 bone maturation 1/313 26/18722 0.35509079327042 0.524575339534532 RHOA 1 GO:0072273 metanephric nephron morphogenesis 1/313 26/18722 0.35509079327042 0.524575339534532 HES1 1 GO:0097066 response to thyroid hormone 1/313 26/18722 0.35509079327042 0.524575339534532 AKR1B1 1 GO:0097186 amelogenesis 1/313 26/18722 0.35509079327042 0.524575339534532 CSF3R 1 GO:0097205 renal filtration 1/313 26/18722 0.35509079327042 0.524575339534532 GJA1 1 GO:1901071 glucosamine-containing compound metabolic process 1/313 26/18722 0.35509079327042 0.524575339534532 EXTL2 1 GO:1902019 regulation of cilium-dependent cell motility 1/313 26/18722 0.35509079327042 0.524575339534532 CCSAP 1 GO:1902186 regulation of viral release from host cell 1/313 26/18722 0.35509079327042 0.524575339534532 CAV2 1 GO:1903523 negative regulation of blood circulation 1/313 26/18722 0.35509079327042 0.524575339534532 SRI 1 GO:1904353 regulation of telomere capping 1/313 26/18722 0.35509079327042 0.524575339534532 MAP3K4 1 GO:1904376 negative regulation of protein localization to cell periphery 1/313 26/18722 0.35509079327042 0.524575339534532 TMBIM1 1 GO:2000108 positive regulation of leukocyte apoptotic process 1/313 26/18722 0.35509079327042 0.524575339534532 ANXA1 1 GO:0034504 protein localization to nucleus 6/313 290/18722 0.356977301530879 0.526999948911008 RPL23/PTTG1IP/MAGED1/PPP1R10/PARP1/FERMT1 6 GO:0048565 digestive tract development 3/313 127/18722 0.357008896307195 0.526999948911008 ID2/CCNB1/HES1 3 GO:0051453 regulation of intracellular pH 2/313 75/18722 0.357684216467187 0.527792175228908 CLIC4/CLN3 2 GO:0007059 chromosome segregation 7/313 346/18722 0.358482052524483 0.528600105172517 NEK6/PTTG1/BIRC5/CDC20/TOP2A/NR3C1/CCNB1 7 GO:0008361 regulation of cell size 4/313 181/18722 0.35864829830854 0.528600105172517 FN1/SEMA6D/RHOA/CLN3 4 GO:1905952 regulation of lipid localization 4/313 181/18722 0.35864829830854 0.528600105172517 CAV1/PLIN2/CYP19A1/DBI 4 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 3/313 128/18722 0.361569466882705 0.532699288089187 GADD45B/PRMT1/MAP3K4 3 GO:0051260 protein homooligomerization 4/313 182/18722 0.362443405387739 0.532874517193375 ALDOA/MIF/FUS/PRMT1 4 GO:0008652 cellular amino acid biosynthetic process 2/313 76/18722 0.36371841577347 0.532874517193375 SERINC5/CLN3 2 GO:0045685 regulation of glial cell differentiation 2/313 76/18722 0.36371841577347 0.532874517193375 ID2/HES1 2 GO:0072028 nephron morphogenesis 2/313 76/18722 0.36371841577347 0.532874517193375 MAGED1/HES1 2 GO:0000027 ribosomal large subunit assembly 1/313 27/18722 0.365887572351847 0.532874517193375 RPL38 1 GO:0000469 cleavage involved in rRNA processing 1/313 27/18722 0.365887572351847 0.532874517193375 RPS21 1 GO:0001835 blastocyst hatching 1/313 27/18722 0.365887572351847 0.532874517193375 STMN3 1 GO:0002825 regulation of T-helper 1 type immune response 1/313 27/18722 0.365887572351847 0.532874517193375 ANXA1 1 GO:0003171 atrioventricular valve development 1/313 27/18722 0.365887572351847 0.532874517193375 SOX4 1 GO:0010561 negative regulation of glycoprotein biosynthetic process 1/313 27/18722 0.365887572351847 0.532874517193375 ITM2B 1 GO:0010586 miRNA metabolic process 1/313 27/18722 0.365887572351847 0.532874517193375 KCNQ1OT1 1 GO:0010758 regulation of macrophage chemotaxis 1/313 27/18722 0.365887572351847 0.532874517193375 MIF 1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 1/313 27/18722 0.365887572351847 0.532874517193375 CCNB1 1 GO:0015813 L-glutamate transmembrane transport 1/313 27/18722 0.365887572351847 0.532874517193375 ITGB1 1 GO:0018126 protein hydroxylation 1/313 27/18722 0.365887572351847 0.532874517193375 P4HA1 1 GO:0018195 peptidyl-arginine modification 1/313 27/18722 0.365887572351847 0.532874517193375 PRMT1 1 GO:0031954 positive regulation of protein autophosphorylation 1/313 27/18722 0.365887572351847 0.532874517193375 CALM1 1 GO:0032703 negative regulation of interleukin-2 production 1/313 27/18722 0.365887572351847 0.532874517193375 EZR 1 GO:0033688 regulation of osteoblast proliferation 1/313 27/18722 0.365887572351847 0.532874517193375 RHOA 1 GO:0034698 response to gonadotropin 1/313 27/18722 0.365887572351847 0.532874517193375 TGFBR3 1 GO:0035188 hatching 1/313 27/18722 0.365887572351847 0.532874517193375 STMN3 1 GO:0035235 ionotropic glutamate receptor signaling pathway 1/313 27/18722 0.365887572351847 0.532874517193375 CLN3 1 GO:0042104 positive regulation of activated T cell proliferation 1/313 27/18722 0.365887572351847 0.532874517193375 IGF2 1 GO:0046174 polyol catabolic process 1/313 27/18722 0.365887572351847 0.532874517193375 TPI1 1 GO:0048520 positive regulation of behavior 1/313 27/18722 0.365887572351847 0.532874517193375 GJA1 1 GO:0071684 organism emergence from protective structure 1/313 27/18722 0.365887572351847 0.532874517193375 STMN3 1 GO:1900746 regulation of vascular endothelial growth factor signaling pathway 1/313 27/18722 0.365887572351847 0.532874517193375 CD63 1 GO:1903203 regulation of oxidative stress-induced neuron death 1/313 27/18722 0.365887572351847 0.532874517193375 PARP1 1 GO:1903421 regulation of synaptic vesicle recycling 1/313 27/18722 0.365887572351847 0.532874517193375 CALM1 1 GO:1904357 negative regulation of telomere maintenance via telomere lengthening 1/313 27/18722 0.365887572351847 0.532874517193375 PARP1 1 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 3/313 129/18722 0.366125186541179 0.533016667366068 PMAIP1/PDCD6/RHOA 3 GO:0000380 alternative mRNA splicing, via spliceosome 2/313 77/18722 0.36973108363098 0.537854885511326 DDX5/TRA2B 2 GO:1901983 regulation of protein acetylation 2/313 77/18722 0.36973108363098 0.537854885511326 ISL1/SOX4 2 GO:0007369 gastrulation 4/313 185/18722 0.373823087403907 0.540683272040375 FN1/WLS/ITGB1/GJA1 4 GO:0000723 telomere maintenance 3/313 131/18722 0.375219848217907 0.540683272040375 PPP1R10/PARP1/MAP3K4 3 GO:0019079 viral genome replication 3/313 131/18722 0.375219848217907 0.540683272040375 DDX5/HACD3/TOP2A 3 GO:0019827 stem cell population maintenance 3/313 131/18722 0.375219848217907 0.540683272040375 LBH/SOX4/HES1 3 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 2/313 78/18722 0.375721254159601 0.540683272040375 PMAIP1/PDCD6 2 GO:0061045 negative regulation of wound healing 2/313 78/18722 0.375721254159601 0.540683272040375 SERPINE1/GJA1 2 GO:0001945 lymph vessel development 1/313 28/18722 0.376504164480965 0.540683272040375 SVEP1 1 GO:0007064 mitotic sister chromatid cohesion 1/313 28/18722 0.376504164480965 0.540683272040375 CDC20 1 GO:0010460 positive regulation of heart rate 1/313 28/18722 0.376504164480965 0.540683272040375 TPM1 1 GO:0010575 positive regulation of vascular endothelial growth factor production 1/313 28/18722 0.376504164480965 0.540683272040375 ISL1 1 GO:0010884 positive regulation of lipid storage 1/313 28/18722 0.376504164480965 0.540683272040375 PLIN2 1 GO:0015740 C4-dicarboxylate transport 1/313 28/18722 0.376504164480965 0.540683272040375 SLC13A3 1 GO:0030262 apoptotic nuclear changes 1/313 28/18722 0.376504164480965 0.540683272040375 TOP2A 1 GO:0031342 negative regulation of cell killing 1/313 28/18722 0.376504164480965 0.540683272040375 SERPINB9 1 GO:0031440 regulation of mRNA 3'-end processing 1/313 28/18722 0.376504164480965 0.540683272040375 CCNB1 1 GO:0032801 receptor catabolic process 1/313 28/18722 0.376504164480965 0.540683272040375 LGMN 1 GO:0034123 positive regulation of toll-like receptor signaling pathway 1/313 28/18722 0.376504164480965 0.540683272040375 CAV1 1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 1/313 28/18722 0.376504164480965 0.540683272040375 ERRFI1 1 GO:0042983 amyloid precursor protein biosynthetic process 1/313 28/18722 0.376504164480965 0.540683272040375 ITM2B 1 GO:0042984 regulation of amyloid precursor protein biosynthetic process 1/313 28/18722 0.376504164480965 0.540683272040375 ITM2B 1 GO:0044331 cell-cell adhesion mediated by cadherin 1/313 28/18722 0.376504164480965 0.540683272040375 CTNND1 1 GO:0045671 negative regulation of osteoclast differentiation 1/313 28/18722 0.376504164480965 0.540683272040375 FBN1 1 GO:0045686 negative regulation of glial cell differentiation 1/313 28/18722 0.376504164480965 0.540683272040375 HES1 1 GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT 1/313 28/18722 0.376504164480965 0.540683272040375 CAV1 1 GO:0051503 adenine nucleotide transport 1/313 28/18722 0.376504164480965 0.540683272040375 GJA1 1 GO:0051894 positive regulation of focal adhesion assembly 1/313 28/18722 0.376504164480965 0.540683272040375 S100A10 1 GO:0060765 regulation of androgen receptor signaling pathway 1/313 28/18722 0.376504164480965 0.540683272040375 DDX5 1 GO:0086011 membrane repolarization during action potential 1/313 28/18722 0.376504164480965 0.540683272040375 CAV1 1 GO:0090200 positive regulation of release of cytochrome c from mitochondria 1/313 28/18722 0.376504164480965 0.540683272040375 PMAIP1 1 GO:1902624 positive regulation of neutrophil migration 1/313 28/18722 0.376504164480965 0.540683272040375 CD99 1 GO:1903649 regulation of cytoplasmic transport 1/313 28/18722 0.376504164480965 0.540683272040375 EZR 1 GO:1903672 positive regulation of sprouting angiogenesis 1/313 28/18722 0.376504164480965 0.540683272040375 PKM 1 GO:1903779 regulation of cardiac conduction 1/313 28/18722 0.376504164480965 0.540683272040375 ATP2B1 1 GO:1990776 response to angiotensin 1/313 28/18722 0.376504164480965 0.540683272040375 CAV1 1 GO:0045667 regulation of osteoblast differentiation 3/313 132/18722 0.379757704428297 0.545149917329762 DDX5/CLIC1/CEBPB 3 GO:1901184 regulation of ERBB signaling pathway 2/313 79/18722 0.381687999570886 0.547714366515779 ERRFI1/LGMN 2 GO:0043543 protein acylation 5/313 243/18722 0.38353596664289 0.548842831876148 MBD3/ISL1/SOX4/MORF4L2/NMT1 5 GO:0001906 cell killing 4/313 188/18722 0.385187074642155 0.548842831876148 GAPDH/SERPINB9/PRDX1/CTSC 4 GO:0016050 vesicle organization 6/313 300/18722 0.386770671908667 0.548842831876148 CAV1/ANXA1/PDCD6/CAV2/S100A10/CLN3 6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 1/313 29/18722 0.386943567311684 0.548842831876148 BTG2 1 GO:0002360 T cell lineage commitment 1/313 29/18722 0.386943567311684 0.548842831876148 RHOA 1 GO:0006734 NADH metabolic process 1/313 29/18722 0.386943567311684 0.548842831876148 ENO1 1 GO:0007143 female meiotic nuclear division 1/313 29/18722 0.386943567311684 0.548842831876148 TOP2A 1 GO:0010955 negative regulation of protein processing 1/313 29/18722 0.386943567311684 0.548842831876148 SERPINE1 1 GO:0015868 purine ribonucleotide transport 1/313 29/18722 0.386943567311684 0.548842831876148 GJA1 1 GO:0021602 cranial nerve morphogenesis 1/313 29/18722 0.386943567311684 0.548842831876148 NRP2 1 GO:0021772 olfactory bulb development 1/313 29/18722 0.386943567311684 0.548842831876148 ID2 1 GO:0030970 retrograde protein transport, ER to cytosol 1/313 29/18722 0.386943567311684 0.548842831876148 HERPUD1 1 GO:0033028 myeloid cell apoptotic process 1/313 29/18722 0.386943567311684 0.548842831876148 ANXA1 1 GO:0035066 positive regulation of histone acetylation 1/313 29/18722 0.386943567311684 0.548842831876148 ISL1 1 GO:0042759 long-chain fatty acid biosynthetic process 1/313 29/18722 0.386943567311684 0.548842831876148 GPX4 1 GO:0043153 entrainment of circadian clock by photoperiod 1/313 29/18722 0.386943567311684 0.548842831876148 ID2 1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity 1/313 29/18722 0.386943567311684 0.548842831876148 CCNB1 1 GO:0048665 neuron fate specification 1/313 29/18722 0.386943567311684 0.548842831876148 ISL1 1 GO:0048679 regulation of axon regeneration 1/313 29/18722 0.386943567311684 0.548842831876148 STK24 1 GO:0051654 establishment of mitochondrion localization 1/313 29/18722 0.386943567311684 0.548842831876148 ARMCX3 1 GO:0051873 killing by host of symbiont cells 1/313 29/18722 0.386943567311684 0.548842831876148 GAPDH 1 GO:0051883 killing of cells in other organism involved in symbiotic interaction 1/313 29/18722 0.386943567311684 0.548842831876148 GAPDH 1 GO:0090114 COPII-coated vesicle budding 1/313 29/18722 0.386943567311684 0.548842831876148 PDCD6 1 GO:0095500 acetylcholine receptor signaling pathway 1/313 29/18722 0.386943567311684 0.548842831876148 LY6E 1 GO:1901017 negative regulation of potassium ion transmembrane transporter activity 1/313 29/18722 0.386943567311684 0.548842831876148 CAV1 1 GO:1902430 negative regulation of amyloid-beta formation 1/313 29/18722 0.386943567311684 0.548842831876148 CLU 1 GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus 1/313 29/18722 0.386943567311684 0.548842831876148 CD63 1 GO:1903318 negative regulation of protein maturation 1/313 29/18722 0.386943567311684 0.548842831876148 SERPINE1 1 GO:1903513 endoplasmic reticulum to cytosol transport 1/313 29/18722 0.386943567311684 0.548842831876148 HERPUD1 1 GO:1903902 positive regulation of viral life cycle 1/313 29/18722 0.386943567311684 0.548842831876148 CAV2 1 GO:2000406 positive regulation of T cell migration 1/313 29/18722 0.386943567311684 0.548842831876148 RHOA 1 GO:0009791 post-embryonic development 2/313 80/18722 0.387630429171529 0.549203216917011 FBN1/C12orf57 2 GO:0071229 cellular response to acid chemical 2/313 80/18722 0.387630429171529 0.549203216917011 CEBPB/DNMT3A 2 GO:1901264 carbohydrate derivative transport 2/313 80/18722 0.387630429171529 0.549203216917011 CLN3/GJA1 2 GO:0098727 maintenance of cell number 3/313 134/18722 0.388811832482936 0.550672115425051 LBH/SOX4/HES1 3 GO:0001558 regulation of cell growth 8/313 414/18722 0.389302885968162 0.551162546255408 FN1/ENO1/SEMA6D/RHOA/HSPA1A/GJA1/EPB41L3/RGS2 8 GO:0042063 gliogenesis 6/313 301/18722 0.38975290957095 0.551594545255245 ANXA1/SOX4/RHOA/CLU/ID2/HES1 6 GO:0006814 sodium ion transport 5/313 245/18722 0.390162363147391 0.551968828131593 SLC6A8/FXYD3/SLC13A4/SLC13A3/PRSS8 5 GO:0099111 microtubule-based transport 4/313 190/18722 0.392749877234279 0.554315846952597 ARMCX3/DST/HSPB1/CLN3 4 GO:0001523 retinoid metabolic process 2/313 81/18722 0.39354768838935 0.554315846952597 RDH13/AKR1B1 2 GO:0001942 hair follicle development 2/313 81/18722 0.39354768838935 0.554315846952597 LGR5/FERMT1 2 GO:0010833 telomere maintenance via telomere lengthening 2/313 81/18722 0.39354768838935 0.554315846952597 PARP1/MAP3K4 2 GO:0030641 regulation of cellular pH 2/313 81/18722 0.39354768838935 0.554315846952597 CLIC4/CLN3 2 GO:0048708 astrocyte differentiation 2/313 81/18722 0.39354768838935 0.554315846952597 ID2/HES1 2 GO:0007162 negative regulation of cell adhesion 6/313 303/18722 0.395716719857274 0.554315846952597 ANXA1/SERPINE1/FBLN1/RHOA/CEBPB/JAM3 6 GO:0003299 muscle hypertrophy in response to stress 1/313 30/18722 0.397208728785575 0.554315846952597 ERRFI1 1 GO:0006099 tricarboxylic acid cycle 1/313 30/18722 0.397208728785575 0.554315846952597 IDH1 1 GO:0006884 cell volume homeostasis 1/313 30/18722 0.397208728785575 0.554315846952597 CLN3 1 GO:0006921 cellular component disassembly involved in execution phase of apoptosis 1/313 30/18722 0.397208728785575 0.554315846952597 TOP2A 1 GO:0007176 regulation of epidermal growth factor-activated receptor activity 1/313 30/18722 0.397208728785575 0.554315846952597 ERRFI1 1 GO:0008209 androgen metabolic process 1/313 30/18722 0.397208728785575 0.554315846952597 CYP19A1 1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation 1/313 30/18722 0.397208728785575 0.554315846952597 CALM1 1 GO:0014887 cardiac muscle adaptation 1/313 30/18722 0.397208728785575 0.554315846952597 ERRFI1 1 GO:0014898 cardiac muscle hypertrophy in response to stress 1/313 30/18722 0.397208728785575 0.554315846952597 ERRFI1 1 GO:0015865 purine nucleotide transport 1/313 30/18722 0.397208728785575 0.554315846952597 GJA1 1 GO:0017145 stem cell division 1/313 30/18722 0.397208728785575 0.554315846952597 LBH 1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 1/313 30/18722 0.397208728785575 0.554315846952597 LGMN 1 GO:0033137 negative regulation of peptidyl-serine phosphorylation 1/313 30/18722 0.397208728785575 0.554315846952597 CAV1 1 GO:0034694 response to prostaglandin 1/313 30/18722 0.397208728785575 0.554315846952597 TGFBR3 1 GO:0036296 response to increased oxygen levels 1/313 30/18722 0.397208728785575 0.554315846952597 CAV1 1 GO:0043032 positive regulation of macrophage activation 1/313 30/18722 0.397208728785575 0.554315846952597 CTSC 1 GO:0045577 regulation of B cell differentiation 1/313 30/18722 0.397208728785575 0.554315846952597 ID2 1 GO:0045948 positive regulation of translational initiation 1/313 30/18722 0.397208728785575 0.554315846952597 PPP1R15A 1 GO:0048147 negative regulation of fibroblast proliferation 1/313 30/18722 0.397208728785575 0.554315846952597 FTH1 1 GO:0048799 animal organ maturation 1/313 30/18722 0.397208728785575 0.554315846952597 RHOA 1 GO:0051125 regulation of actin nucleation 1/313 30/18722 0.397208728785575 0.554315846952597 SCIN 1 GO:0060292 long-term synaptic depression 1/313 30/18722 0.397208728785575 0.554315846952597 PLK2 1 GO:0061311 cell surface receptor signaling pathway involved in heart development 1/313 30/18722 0.397208728785575 0.554315846952597 GALNT11 1 GO:0070498 interleukin-1-mediated signaling pathway 1/313 30/18722 0.397208728785575 0.554315846952597 EGR1 1 GO:0090314 positive regulation of protein targeting to membrane 1/313 30/18722 0.397208728785575 0.554315846952597 TCAF1 1 GO:1900101 regulation of endoplasmic reticulum unfolded protein response 1/313 30/18722 0.397208728785575 0.554315846952597 PPP1R15A 1 GO:1902751 positive regulation of cell cycle G2/M phase transition 1/313 30/18722 0.397208728785575 0.554315846952597 CCNB1 1 GO:1903019 negative regulation of glycoprotein metabolic process 1/313 30/18722 0.397208728785575 0.554315846952597 ITM2B 1 GO:2000637 positive regulation of gene silencing by miRNA 1/313 30/18722 0.397208728785575 0.554315846952597 DDX5 1 GO:2000648 positive regulation of stem cell proliferation 1/313 30/18722 0.397208728785575 0.554315846952597 GJA1 1 GO:1900180 regulation of protein localization to nucleus 3/313 136/18722 0.397833790431142 0.554984697754253 MAGED1/PARP1/FERMT1 3 GO:2001252 positive regulation of chromosome organization 2/313 82/18722 0.399438957821298 0.557019821401349 PPP1R10/MAP3K4 2 GO:0000086 G2/M transition of mitotic cell cycle 3/313 137/18722 0.402331473040067 0.560642722497633 BACH1/CALM1/CCNB1 3 GO:0045471 response to ethanol 3/313 137/18722 0.402331473040067 0.560642722497633 RHOA/DNMT3A/RGS2 3 GO:0006650 glycerophospholipid metabolic process 6/313 306/18722 0.404658247592161 0.562219289361725 ABHD8/DBI/SERINC5/CLN3/PRDX6/PGP 6 GO:0002237 response to molecule of bacterial origin 7/313 363/18722 0.404905044435382 0.562219289361725 FOS/JUN/SERPINE1/RHOA/CEBPB/PDE4B/GJA1 7 GO:0046785 microtubule polymerization 2/313 83/18722 0.405303452303025 0.562219289361725 HSPA1A/STMN1 2 GO:0050886 endocrine process 2/313 83/18722 0.405303452303025 0.562219289361725 RHOA/GJA1 2 GO:0055076 transition metal ion homeostasis 3/313 138/18722 0.406819654670373 0.562219289361725 FTL/FTH1/SRI 3 GO:0002828 regulation of type 2 immune response 1/313 31/18722 0.407302547953674 0.562219289361725 ANXA1 1 GO:0008045 motor neuron axon guidance 1/313 31/18722 0.407302547953674 0.562219289361725 LAMC2 1 GO:0018200 peptidyl-glutamic acid modification 1/313 31/18722 0.407302547953674 0.562219289361725 PARP1 1 GO:0021988 olfactory lobe development 1/313 31/18722 0.407302547953674 0.562219289361725 ID2 1 GO:0030201 heparan sulfate proteoglycan metabolic process 1/313 31/18722 0.407302547953674 0.562219289361725 EXTL2 1 GO:0030212 hyaluronan metabolic process 1/313 31/18722 0.407302547953674 0.562219289361725 ITIH5 1 GO:0032148 activation of protein kinase B activity 1/313 31/18722 0.407302547953674 0.562219289361725 INSR 1 GO:0033238 regulation of cellular amine metabolic process 1/313 31/18722 0.407302547953674 0.562219289361725 CLN3 1 GO:0036475 neuron death in response to oxidative stress 1/313 31/18722 0.407302547953674 0.562219289361725 PARP1 1 GO:0042133 neurotransmitter metabolic process 1/313 31/18722 0.407302547953674 0.562219289361725 CLN3 1 GO:0045987 positive regulation of smooth muscle contraction 1/313 31/18722 0.407302547953674 0.562219289361725 RHOA 1 GO:0048566 embryonic digestive tract development 1/313 31/18722 0.407302547953674 0.562219289361725 ID2 1 GO:0050482 arachidonic acid secretion 1/313 31/18722 0.407302547953674 0.562219289361725 ANXA1 1 GO:0060148 positive regulation of posttranscriptional gene silencing 1/313 31/18722 0.407302547953674 0.562219289361725 DDX5 1 GO:0060390 regulation of SMAD protein signal transduction 1/313 31/18722 0.407302547953674 0.562219289361725 PARP1 1 GO:0071480 cellular response to gamma radiation 1/313 31/18722 0.407302547953674 0.562219289361725 EGR1 1 GO:0090183 regulation of kidney development 1/313 31/18722 0.407302547953674 0.562219289361725 MAGED1 1 GO:1903963 arachidonate transport 1/313 31/18722 0.407302547953674 0.562219289361725 ANXA1 1 GO:1905144 response to acetylcholine 1/313 31/18722 0.407302547953674 0.562219289361725 LY6E 1 GO:1905145 cellular response to acetylcholine 1/313 31/18722 0.407302547953674 0.562219289361725 LY6E 1 GO:2000144 positive regulation of DNA-templated transcription, initiation 1/313 31/18722 0.407302547953674 0.562219289361725 JUN 1 GO:0072594 establishment of protein localization to organelle 8/313 422/18722 0.409624869224764 0.565219962717896 RPL23/PTTG1IP/HERPUD1/PPP1R10/CALM1/NMT1/CLU/FERMT1 8 GO:0010921 regulation of phosphatase activity 2/313 84/18722 0.411140419999574 0.566080137048238 CALM1/PPP1R15A 2 GO:0015844 monoamine transport 2/313 84/18722 0.411140419999574 0.566080137048238 LY6E/ACTB 2 GO:0022404 molting cycle process 2/313 84/18722 0.411140419999574 0.566080137048238 LGR5/FERMT1 2 GO:0022405 hair cycle process 2/313 84/18722 0.411140419999574 0.566080137048238 LGR5/FERMT1 2 GO:0032508 DNA duplex unwinding 2/313 84/18722 0.411140419999574 0.566080137048238 ANXA1/TOP2A 2 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 2/313 84/18722 0.411140419999574 0.566080137048238 SOX4/PLK2 2 GO:0030705 cytoskeleton-dependent intracellular transport 4/313 195/18722 0.411591967213372 0.566496970058318 ARMCX3/DST/HSPB1/CLN3 4 GO:0070372 regulation of ERK1 and ERK2 cascade 6/313 309/18722 0.413590774533161 0.569042312485632 FN1/MIF/TIMP3/FBLN1/EZR/ERRFI1 6 GO:0008654 phospholipid biosynthetic process 5/313 253/18722 0.41660396352762 0.56931416599015 IDH1/ABHD8/SERINC5/ISYNA1/CLN3 5 GO:0030433 ubiquitin-dependent ERAD pathway 2/313 85/18722 0.416949141516743 0.56931416599015 CAV1/HERPUD1 2 GO:0032092 positive regulation of protein binding 2/313 85/18722 0.416949141516743 0.56931416599015 CAV1/PLK2 2 GO:0072384 organelle transport along microtubule 2/313 85/18722 0.416949141516743 0.56931416599015 ARMCX3/CLN3 2 GO:0097194 execution phase of apoptosis 2/313 85/18722 0.416949141516743 0.56931416599015 STK24/TOP2A 2 GO:0098773 skin epidermis development 2/313 85/18722 0.416949141516743 0.56931416599015 LGR5/FERMT1 2 GO:2000779 regulation of double-strand break repair 2/313 85/18722 0.416949141516743 0.56931416599015 FUS/PARP1 2 GO:0003338 metanephros morphogenesis 1/313 32/18722 0.417227875784743 0.56931416599015 HES1 1 GO:0010039 response to iron ion 1/313 32/18722 0.417227875784743 0.56931416599015 CCNB1 1 GO:0010667 negative regulation of cardiac muscle cell apoptotic process 1/313 32/18722 0.417227875784743 0.56931416599015 PPP1R10 1 GO:0030431 sleep 1/313 32/18722 0.417227875784743 0.56931416599015 FOS 1 GO:0033687 osteoblast proliferation 1/313 32/18722 0.417227875784743 0.56931416599015 RHOA 1 GO:0035883 enteroendocrine cell differentiation 1/313 32/18722 0.417227875784743 0.56931416599015 HES1 1 GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 1/313 32/18722 0.417227875784743 0.56931416599015 ANXA1 1 GO:0045761 regulation of adenylate cyclase activity 1/313 32/18722 0.417227875784743 0.56931416599015 TIMP2 1 GO:0046475 glycerophospholipid catabolic process 1/313 32/18722 0.417227875784743 0.56931416599015 PRDX6 1 GO:0048841 regulation of axon extension involved in axon guidance 1/313 32/18722 0.417227875784743 0.56931416599015 SEMA6D 1 GO:0051642 centrosome localization 1/313 32/18722 0.417227875784743 0.56931416599015 EZR 1 GO:0060317 cardiac epithelial to mesenchymal transition 1/313 32/18722 0.417227875784743 0.56931416599015 TGFBR3 1 GO:0090022 regulation of neutrophil chemotaxis 1/313 32/18722 0.417227875784743 0.56931416599015 JAM3 1 GO:1901532 regulation of hematopoietic progenitor cell differentiation 1/313 32/18722 0.417227875784743 0.56931416599015 HES1 1 GO:1905476 negative regulation of protein localization to membrane 1/313 32/18722 0.417227875784743 0.56931416599015 TMBIM1 1 GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 1/313 32/18722 0.417227875784743 0.56931416599015 ANXA1 1 GO:0016241 regulation of macroautophagy 3/313 141/18722 0.420222596592838 0.572579608170699 GAPDH/CLN3/EXOC1 3 GO:0030183 B cell differentiation 3/313 141/18722 0.420222596592838 0.572579608170699 TPD52/ITGB1/ID2 3 GO:0034341 response to interferon-gamma 3/313 141/18722 0.420222596592838 0.572579608170699 GAPDH/FLNB/ACTG1 3 GO:0048284 organelle fusion 3/313 141/18722 0.420222596592838 0.572579608170699 ANXA1/CAV2/CLN3 3 GO:1903510 mucopolysaccharide metabolic process 2/313 86/18722 0.422728929032687 0.575734408194417 ITIH5/B3GNT2 2 GO:0048167 regulation of synaptic plasticity 4/313 198/18722 0.422840400659729 0.575734408194417 CLN3/CDC20/PLK2/LGMN 4 GO:0046467 membrane lipid biosynthetic process 3/313 142/18722 0.424668227600227 0.575820571470244 ORMDL1/HACD3/SPTSSA 3 GO:0072006 nephron development 3/313 142/18722 0.424668227600227 0.575820571470244 MAGED1/EGR1/HES1 3 GO:0090596 sensory organ morphogenesis 5/313 256/18722 0.426477587580855 0.575820571470244 RDH13/FBN1/RPL38/C12orf57/MFAP5 5 GO:0006654 phosphatidic acid biosynthetic process 1/313 33/18722 0.426987515960205 0.575820571470244 ABHD8 1 GO:0009648 photoperiodism 1/313 33/18722 0.426987515960205 0.575820571470244 ID2 1 GO:0010165 response to X-ray 1/313 33/18722 0.426987515960205 0.575820571470244 ANXA1 1 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 1/313 33/18722 0.426987515960205 0.575820571470244 PDCD6 1 GO:0031116 positive regulation of microtubule polymerization 1/313 33/18722 0.426987515960205 0.575820571470244 HSPA1A 1 GO:0032228 regulation of synaptic transmission, GABAergic 1/313 33/18722 0.426987515960205 0.575820571470244 CLN3 1 GO:0040020 regulation of meiotic nuclear division 1/313 33/18722 0.426987515960205 0.575820571470244 CDC20 1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 1/313 33/18722 0.426987515960205 0.575820571470244 FLT1 1 GO:0045920 negative regulation of exocytosis 1/313 33/18722 0.426987515960205 0.575820571470244 ANXA1 1 GO:0046685 response to arsenic-containing substance 1/313 33/18722 0.426987515960205 0.575820571470244 GSTO1 1 GO:0050901 leukocyte tethering or rolling 1/313 33/18722 0.426987515960205 0.575820571470244 ITGB1 1 GO:0060122 inner ear receptor cell stereocilium organization 1/313 33/18722 0.426987515960205 0.575820571470244 HES1 1 GO:0061842 microtubule organizing center localization 1/313 33/18722 0.426987515960205 0.575820571470244 EZR 1 GO:0070570 regulation of neuron projection regeneration 1/313 33/18722 0.426987515960205 0.575820571470244 STK24 1 GO:0071295 cellular response to vitamin 1/313 33/18722 0.426987515960205 0.575820571470244 ATP2B1 1 GO:0071763 nuclear membrane organization 1/313 33/18722 0.426987515960205 0.575820571470244 NEK6 1 GO:0150117 positive regulation of cell-substrate junction organization 1/313 33/18722 0.426987515960205 0.575820571470244 S100A10 1 GO:1901099 negative regulation of signal transduction in absence of ligand 1/313 33/18722 0.426987515960205 0.575820571470244 HSPA1A 1 GO:1901380 negative regulation of potassium ion transmembrane transport 1/313 33/18722 0.426987515960205 0.575820571470244 CAV1 1 GO:1902992 negative regulation of amyloid precursor protein catabolic process 1/313 33/18722 0.426987515960205 0.575820571470244 CLU 1 GO:1903715 regulation of aerobic respiration 1/313 33/18722 0.426987515960205 0.575820571470244 RHOA 1 GO:1904031 positive regulation of cyclin-dependent protein kinase activity 1/313 33/18722 0.426987515960205 0.575820571470244 CCNB1 1 GO:2000036 regulation of stem cell population maintenance 1/313 33/18722 0.426987515960205 0.575820571470244 LBH 1 GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 1/313 33/18722 0.426987515960205 0.575820571470244 HSPA1A 1 GO:0016101 diterpenoid metabolic process 2/313 87/18722 0.428479125449333 0.57762748958414 RDH13/AKR1B1 2 GO:0038061 NIK/NF-kappaB signaling 3/313 143/18722 0.429102134392366 0.57805797085341 PRDX1/RHOA/TMSB4X 3 GO:0070555 response to interleukin-1 3/313 143/18722 0.429102134392366 0.57805797085341 ANXA1/CEBPB/EGR1 3 GO:0014065 phosphatidylinositol 3-kinase signaling 3/313 144/18722 0.433523902115147 0.581959435249418 FN1/INSR/FLT1 3 GO:0006473 protein acetylation 4/313 201/18722 0.434036526793866 0.581959435249418 MBD3/ISL1/SOX4/MORF4L2 4 GO:0009952 anterior/posterior pattern specification 4/313 201/18722 0.434036526793866 0.581959435249418 WLS/BTG2/BHLHE41/HES1 4 GO:0051054 positive regulation of DNA metabolic process 4/313 201/18722 0.434036526793866 0.581959435249418 FUS/PPP1R10/PARP1/MAP3K4 4 GO:0043414 macromolecule methylation 6/313 316/18722 0.434373919096964 0.581959435249418 MBD3/FOS/PRMT1/PARP1/BTG2/DNMT3A 6 GO:0010498 proteasomal protein catabolic process 9/313 490/18722 0.434772211935637 0.581959435249418 CAV1/PMAIP1/GPX1/DDA1/HERPUD1/HSPA1A/CDC20/CLU/PLK2 9 GO:0030098 lymphocyte differentiation 7/313 374/18722 0.434925915064994 0.581959435249418 ANXA1/SOX4/RHOA/TPD52/ITGB1/EGR1/ID2 7 GO:0001662 behavioral fear response 1/313 34/18722 0.436584225655986 0.581959435249418 GJA1 1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 1/313 34/18722 0.436584225655986 0.581959435249418 LGMN 1 GO:0009649 entrainment of circadian clock 1/313 34/18722 0.436584225655986 0.581959435249418 ID2 1 GO:0014072 response to isoquinoline alkaloid 1/313 34/18722 0.436584225655986 0.581959435249418 FOSB 1 GO:0019076 viral release from host cell 1/313 34/18722 0.436584225655986 0.581959435249418 CAV2 1 GO:0019320 hexose catabolic process 1/313 34/18722 0.436584225655986 0.581959435249418 ENO1 1 GO:0032212 positive regulation of telomere maintenance via telomerase 1/313 34/18722 0.436584225655986 0.581959435249418 MAP3K4 1 GO:0032770 positive regulation of monooxygenase activity 1/313 34/18722 0.436584225655986 0.581959435249418 CALM1 1 GO:0035308 negative regulation of protein dephosphorylation 1/313 34/18722 0.436584225655986 0.581959435249418 PPP1R15A 1 GO:0035890 exit from host 1/313 34/18722 0.436584225655986 0.581959435249418 CAV2 1 GO:0035891 exit from host cell 1/313 34/18722 0.436584225655986 0.581959435249418 CAV2 1 GO:0043278 response to morphine 1/313 34/18722 0.436584225655986 0.581959435249418 FOSB 1 GO:0050869 negative regulation of B cell activation 1/313 34/18722 0.436584225655986 0.581959435249418 ID2 1 GO:0050931 pigment cell differentiation 1/313 34/18722 0.436584225655986 0.581959435249418 CD63 1 GO:0051973 positive regulation of telomerase activity 1/313 34/18722 0.436584225655986 0.581959435249418 MAP3K4 1 GO:0055094 response to lipoprotein particle 1/313 34/18722 0.436584225655986 0.581959435249418 ITGB1 1 GO:0070050 neuron cellular homeostasis 1/313 34/18722 0.436584225655986 0.581959435249418 ATP2B1 1 GO:0070884 regulation of calcineurin-NFAT signaling cascade 1/313 34/18722 0.436584225655986 0.581959435249418 FHL2 1 GO:0086019 cell-cell signaling involved in cardiac conduction 1/313 34/18722 0.436584225655986 0.581959435249418 GJA1 1 GO:0098751 bone cell development 1/313 34/18722 0.436584225655986 0.581959435249418 FBN1 1 GO:1904893 negative regulation of receptor signaling pathway via STAT 1/313 34/18722 0.436584225655986 0.581959435249418 CAV1 1 GO:1990000 amyloid fibril formation 1/313 34/18722 0.436584225655986 0.581959435249418 CLU 1 GO:2000352 negative regulation of endothelial cell apoptotic process 1/313 34/18722 0.436584225655986 0.581959435249418 SERPINE1 1 GO:1903046 meiotic cell cycle process 4/313 202/18722 0.437755634782682 0.583316661399255 MYH9/PTTG1/CDC20/TOP2A 4 GO:0061351 neural precursor cell proliferation 3/313 145/18722 0.437933125654349 0.583348988581563 RHOA/BTG2/ID2 3 GO:0090150 establishment of protein localization to membrane 5/313 260/18722 0.439592202686837 0.585354150272399 KRT18/TCAF1/CALM1/CLN3/NMT1 5 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 3/313 146/18722 0.442329409549518 0.588154093175533 PDE4B/LGR5/ARRDC3 3 GO:0045580 regulation of T cell differentiation 3/313 146/18722 0.442329409549518 0.588154093175533 ANXA1/SOX4/RHOA 3 GO:0002028 regulation of sodium ion transport 2/313 90/18722 0.445546040699016 0.588154093175533 FXYD3/PRSS8 2 GO:0035304 regulation of protein dephosphorylation 2/313 90/18722 0.445546040699016 0.588154093175533 CALM1/PPP1R15A 2 GO:0045638 negative regulation of myeloid cell differentiation 2/313 90/18722 0.445546040699016 0.588154093175533 FBN1/PRMT1 2 GO:0048477 oogenesis 2/313 90/18722 0.445546040699016 0.588154093175533 LGR5/CCNB1 2 GO:0061097 regulation of protein tyrosine kinase activity 2/313 90/18722 0.445546040699016 0.588154093175533 CAV1/ERRFI1 2 GO:0099175 regulation of postsynapse organization 2/313 90/18722 0.445546040699016 0.588154093175533 NRP2/CFL1 2 GO:0000460 maturation of 5.8S rRNA 1/313 35/18722 0.446020716311469 0.588154093175533 RPS21 1 GO:0002209 behavioral defense response 1/313 35/18722 0.446020716311469 0.588154093175533 GJA1 1 GO:0003298 physiological muscle hypertrophy 1/313 35/18722 0.446020716311469 0.588154093175533 RGS2 1 GO:0003301 physiological cardiac muscle hypertrophy 1/313 35/18722 0.446020716311469 0.588154093175533 RGS2 1 GO:0006084 acetyl-CoA metabolic process 1/313 35/18722 0.446020716311469 0.588154093175533 MPC2 1 GO:0006471 protein ADP-ribosylation 1/313 35/18722 0.446020716311469 0.588154093175533 PARP1 1 GO:0007020 microtubule nucleation 1/313 35/18722 0.446020716311469 0.588154093175533 HSPA1A 1 GO:0008608 attachment of spindle microtubules to kinetochore 1/313 35/18722 0.446020716311469 0.588154093175533 CCNB1 1 GO:0010664 negative regulation of striated muscle cell apoptotic process 1/313 35/18722 0.446020716311469 0.588154093175533 PPP1R10 1 GO:0010765 positive regulation of sodium ion transport 1/313 35/18722 0.446020716311469 0.588154093175533 PRSS8 1 GO:0021955 central nervous system neuron axonogenesis 1/313 35/18722 0.446020716311469 0.588154093175533 C12orf57 1 GO:0032205 negative regulation of telomere maintenance 1/313 35/18722 0.446020716311469 0.588154093175533 PARP1 1 GO:0039694 viral RNA genome replication 1/313 35/18722 0.446020716311469 0.588154093175533 TOP2A 1 GO:0042462 eye photoreceptor cell development 1/313 35/18722 0.446020716311469 0.588154093175533 RDH13 1 GO:0061049 cell growth involved in cardiac muscle cell development 1/313 35/18722 0.446020716311469 0.588154093175533 RGS2 1 GO:0097421 liver regeneration 1/313 35/18722 0.446020716311469 0.588154093175533 CEBPB 1 GO:0098801 regulation of renal system process 1/313 35/18722 0.446020716311469 0.588154093175533 GJA1 1 GO:0098810 neurotransmitter reuptake 1/313 35/18722 0.446020716311469 0.588154093175533 ITGB1 1 GO:0106056 regulation of calcineurin-mediated signaling 1/313 35/18722 0.446020716311469 0.588154093175533 FHL2 1 GO:2000403 positive regulation of lymphocyte migration 1/313 35/18722 0.446020716311469 0.588154093175533 RHOA 1 GO:0060041 retina development in camera-type eye 3/313 147/18722 0.446712367905976 0.588454665957803 RDH13/ATP2B1/CLIC4 3 GO:1902652 secondary alcohol metabolic process 3/313 147/18722 0.446712367905976 0.588454665957803 CYP11A1/IDH1/DHCR24 3 GO:1903531 negative regulation of secretion by cell 3/313 147/18722 0.446712367905976 0.588454665957803 ANXA1/TNFRSF1A/GJA1 3 GO:0044839 cell cycle G2/M phase transition 3/313 148/18722 0.45108162430509 0.593302720568777 BACH1/CALM1/CCNB1 3 GO:0001657 ureteric bud development 2/313 91/18722 0.451171887587762 0.593302720568777 MAGED1/HES1 2 GO:0006885 regulation of pH 2/313 91/18722 0.451171887587762 0.593302720568777 CLIC4/CLN3 2 GO:0072080 nephron tubule development 2/313 91/18722 0.451171887587762 0.593302720568777 MAGED1/HES1 2 GO:0098661 inorganic anion transmembrane transport 2/313 91/18722 0.451171887587762 0.593302720568777 SLC26A2/SLC13A4 2 GO:0051090 regulation of DNA-binding transcription factor activity 8/313 440/18722 0.455223097802293 0.595414815312854 CAV1/ANXA4/SRI/TMSB4X/HSPA1A/CLU/ID2/HES1 8 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 1/313 36/18722 0.455299654385773 0.595414815312854 LGMN 1 GO:0003203 endocardial cushion morphogenesis 1/313 36/18722 0.455299654385773 0.595414815312854 ISL1 1 GO:0003352 regulation of cilium movement 1/313 36/18722 0.455299654385773 0.595414815312854 CCSAP 1 GO:0006699 bile acid biosynthetic process 1/313 36/18722 0.455299654385773 0.595414815312854 SLC27A2 1 GO:0010092 specification of animal organ identity 1/313 36/18722 0.455299654385773 0.595414815312854 ISL1 1 GO:0010923 negative regulation of phosphatase activity 1/313 36/18722 0.455299654385773 0.595414815312854 PPP1R15A 1 GO:0042092 type 2 immune response 1/313 36/18722 0.455299654385773 0.595414815312854 ANXA1 1 GO:0043949 regulation of cAMP-mediated signaling 1/313 36/18722 0.455299654385773 0.595414815312854 RGS2 1 GO:0044060 regulation of endocrine process 1/313 36/18722 0.455299654385773 0.595414815312854 GJA1 1 GO:0051354 negative regulation of oxidoreductase activity 1/313 36/18722 0.455299654385773 0.595414815312854 CAV1 1 GO:0060251 regulation of glial cell proliferation 1/313 36/18722 0.455299654385773 0.595414815312854 HES1 1 GO:0071402 cellular response to lipoprotein particle stimulus 1/313 36/18722 0.455299654385773 0.595414815312854 ITGB1 1 GO:0090313 regulation of protein targeting to membrane 1/313 36/18722 0.455299654385773 0.595414815312854 TCAF1 1 GO:1903749 positive regulation of establishment of protein localization to mitochondrion 1/313 36/18722 0.455299654385773 0.595414815312854 NMT1 1 GO:0009411 response to UV 3/313 149/18722 0.455436811712906 0.595414815312854 GPX1/PARP1/MAP3K4 3 GO:0032368 regulation of lipid transport 3/313 149/18722 0.455436811712906 0.595414815312854 CAV1/CYP19A1/DBI 3 GO:0006497 protein lipidation 2/313 92/18722 0.456765290378312 0.596332462438352 DBI/NMT1 2 GO:0031058 positive regulation of histone modification 2/313 92/18722 0.456765290378312 0.596332462438352 ISL1/CCNB1 2 GO:0072163 mesonephric epithelium development 2/313 92/18722 0.456765290378312 0.596332462438352 MAGED1/HES1 2 GO:0072164 mesonephric tubule development 2/313 92/18722 0.456765290378312 0.596332462438352 MAGED1/HES1 2 GO:0019217 regulation of fatty acid metabolic process 2/313 93/18722 0.462325759553191 0.601381252251922 CAV1/ANXA1 2 GO:0032088 negative regulation of NF-kappaB transcription factor activity 2/313 93/18722 0.462325759553191 0.601381252251922 ANXA4/TMSB4X 2 GO:0045132 meiotic chromosome segregation 2/313 93/18722 0.462325759553191 0.601381252251922 PTTG1/TOP2A 2 GO:0097306 cellular response to alcohol 2/313 93/18722 0.462325759553191 0.601381252251922 ATP2B1/DNMT3A 2 GO:1902807 negative regulation of cell cycle G1/S phase transition 2/313 93/18722 0.462325759553191 0.601381252251922 SOX4/PLK2 2 GO:0071222 cellular response to lipopolysaccharide 4/313 209/18722 0.463581038553175 0.601381252251922 SERPINE1/RHOA/CEBPB/PDE4B 4 GO:0030902 hindbrain development 3/313 151/18722 0.464103557783496 0.601381252251922 WLS/ITGB1/HES1 3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/313 37/18722 0.464423662101563 0.601381252251922 RPS21 1 GO:0001990 regulation of systemic arterial blood pressure by hormone 1/313 37/18722 0.464423662101563 0.601381252251922 RHOA 1 GO:0003176 aortic valve development 1/313 37/18722 0.464423662101563 0.601381252251922 TNFRSF1A 1 GO:0006623 protein targeting to vacuole 1/313 37/18722 0.464423662101563 0.601381252251922 CLU 1 GO:0006862 nucleotide transport 1/313 37/18722 0.464423662101563 0.601381252251922 GJA1 1 GO:0007340 acrosome reaction 1/313 37/18722 0.464423662101563 0.601381252251922 SPESP1 1 GO:0031112 positive regulation of microtubule polymerization or depolymerization 1/313 37/18722 0.464423662101563 0.601381252251922 HSPA1A 1 GO:0042401 cellular biogenic amine biosynthetic process 1/313 37/18722 0.464423662101563 0.601381252251922 OAZ1 1 GO:0043029 T cell homeostasis 1/313 37/18722 0.464423662101563 0.601381252251922 PMAIP1 1 GO:0045616 regulation of keratinocyte differentiation 1/313 37/18722 0.464423662101563 0.601381252251922 ERRFI1 1 GO:0046473 phosphatidic acid metabolic process 1/313 37/18722 0.464423662101563 0.601381252251922 ABHD8 1 GO:0048009 insulin-like growth factor receptor signaling pathway 1/313 37/18722 0.464423662101563 0.601381252251922 IGFBP3 1 GO:0051954 positive regulation of amine transport 1/313 37/18722 0.464423662101563 0.601381252251922 ITGB1 1 GO:0060306 regulation of membrane repolarization 1/313 37/18722 0.464423662101563 0.601381252251922 CAV1 1 GO:0060428 lung epithelium development 1/313 37/18722 0.464423662101563 0.601381252251922 ERRFI1 1 GO:0090218 positive regulation of lipid kinase activity 1/313 37/18722 0.464423662101563 0.601381252251922 FLT1 1 GO:1904358 positive regulation of telomere maintenance via telomere lengthening 1/313 37/18722 0.464423662101563 0.601381252251922 MAP3K4 1 GO:0010975 regulation of neuron projection development 8/313 445/18722 0.467799278939108 0.605108153764079 FN1/RAB17/SEMA6D/CFL1/RHOA/STK24/CDC20/RGS2 8 GO:0019080 viral gene expression 2/313 94/18722 0.467852830899483 0.605108153764079 JUN/SSB 2 GO:1903035 negative regulation of response to wounding 2/313 94/18722 0.467852830899483 0.605108153764079 SERPINE1/GJA1 2 GO:0008643 carbohydrate transport 3/313 152/18722 0.468414428458823 0.605108153764079 EZR/INSR/SLC2A1 3 GO:0016573 histone acetylation 3/313 152/18722 0.468414428458823 0.605108153764079 MBD3/ISL1/MORF4L2 3 GO:0031056 regulation of histone modification 3/313 152/18722 0.468414428458823 0.605108153764079 IGF2/ISL1/CCNB1 3 GO:0051092 positive regulation of NF-kappaB transcription factor activity 3/313 152/18722 0.468414428458823 0.605108153764079 CAV1/HSPA1A/CLU 3 GO:0030516 regulation of axon extension 2/313 95/18722 0.473346064804451 0.607420281866648 FN1/SEMA6D 2 GO:0048709 oligodendrocyte differentiation 2/313 95/18722 0.473346064804451 0.607420281866648 CLU/HES1 2 GO:0002385 mucosal immune response 1/313 38/18722 0.473395318176608 0.607420281866648 RAB17 1 GO:0002478 antigen processing and presentation of exogenous peptide antigen 1/313 38/18722 0.473395318176608 0.607420281866648 LGMN 1 GO:0007094 mitotic spindle assembly checkpoint signaling 1/313 38/18722 0.473395318176608 0.607420281866648 CCNB1 1 GO:0009309 amine biosynthetic process 1/313 38/18722 0.473395318176608 0.607420281866648 OAZ1 1 GO:0010613 positive regulation of cardiac muscle hypertrophy 1/313 38/18722 0.473395318176608 0.607420281866648 PARP1 1 GO:0032373 positive regulation of sterol transport 1/313 38/18722 0.473395318176608 0.607420281866648 CAV1 1 GO:0032376 positive regulation of cholesterol transport 1/313 38/18722 0.473395318176608 0.607420281866648 CAV1 1 GO:0035337 fatty-acyl-CoA metabolic process 1/313 38/18722 0.473395318176608 0.607420281866648 TECR 1 GO:0035886 vascular associated smooth muscle cell differentiation 1/313 38/18722 0.473395318176608 0.607420281866648 HES1 1 GO:0042596 fear response 1/313 38/18722 0.473395318176608 0.607420281866648 GJA1 1 GO:0048246 macrophage chemotaxis 1/313 38/18722 0.473395318176608 0.607420281866648 MIF 1 GO:0048713 regulation of oligodendrocyte differentiation 1/313 38/18722 0.473395318176608 0.607420281866648 HES1 1 GO:0071173 spindle assembly checkpoint signaling 1/313 38/18722 0.473395318176608 0.607420281866648 CCNB1 1 GO:0071174 mitotic spindle checkpoint signaling 1/313 38/18722 0.473395318176608 0.607420281866648 CCNB1 1 GO:0071398 cellular response to fatty acid 1/313 38/18722 0.473395318176608 0.607420281866648 CCNB1 1 GO:0098926 postsynaptic signal transduction 1/313 38/18722 0.473395318176608 0.607420281866648 LY6E 1 GO:1903725 regulation of phospholipid metabolic process 1/313 38/18722 0.473395318176608 0.607420281866648 IDH1 1 GO:2000279 negative regulation of DNA biosynthetic process 1/313 38/18722 0.473395318176608 0.607420281866648 GJA1 1 GO:0022407 regulation of cell-cell adhesion 8/313 448/18722 0.475316417207776 0.609679784471026 IGF2/CAV1/EFNB1/ANXA1/SOX4/RHOA/CEBPB/HES1 8 GO:0070371 ERK1 and ERK2 cascade 6/313 330/18722 0.475511818105324 0.609724988725823 FN1/MIF/TIMP3/FBLN1/EZR/ERRFI1 6 GO:0007605 sensory perception of sound 3/313 154/18722 0.476989512803033 0.611413830047524 RPL38/GPX1/BIRC5 3 GO:0043583 ear development 4/313 213/18722 0.478152744308499 0.612503631880221 RPL38/LGR5/MCOLN3/HES1 4 GO:0001823 mesonephros development 2/313 96/18722 0.478805045567517 0.612503631880221 MAGED1/HES1 2 GO:0006637 acyl-CoA metabolic process 2/313 96/18722 0.478805045567517 0.612503631880221 MPC2/TECR 2 GO:0010769 regulation of cell morphogenesis involved in differentiation 2/313 96/18722 0.478805045567517 0.612503631880221 FBLN1/S100A10 2 GO:0035383 thioester metabolic process 2/313 96/18722 0.478805045567517 0.612503631880221 MPC2/TECR 2 GO:0042158 lipoprotein biosynthetic process 2/313 96/18722 0.478805045567517 0.612503631880221 DBI/NMT1 2 GO:0046434 organophosphate catabolic process 3/313 155/18722 0.481253092218941 0.61398017477399 IDH1/PDE4B/PRDX6 3 GO:0044242 cellular lipid catabolic process 4/313 214/18722 0.481772214891357 0.61398017477399 CROT/IDH1/SLC27A2/PRDX6 4 GO:0002701 negative regulation of production of molecular mediator of immune response 1/313 39/18722 0.48221715854327 0.61398017477399 TMBIM6 1 GO:0014742 positive regulation of muscle hypertrophy 1/313 39/18722 0.48221715854327 0.61398017477399 PARP1 1 GO:0016233 telomere capping 1/313 39/18722 0.48221715854327 0.61398017477399 MAP3K4 1 GO:0016572 histone phosphorylation 1/313 39/18722 0.48221715854327 0.61398017477399 CCNB1 1 GO:0031577 spindle checkpoint signaling 1/313 39/18722 0.48221715854327 0.61398017477399 CCNB1 1 GO:0034314 Arp2/3 complex-mediated actin nucleation 1/313 39/18722 0.48221715854327 0.61398017477399 IQGAP2 1 GO:0043267 negative regulation of potassium ion transport 1/313 39/18722 0.48221715854327 0.61398017477399 CAV1 1 GO:0045622 regulation of T-helper cell differentiation 1/313 39/18722 0.48221715854327 0.61398017477399 ANXA1 1 GO:0045923 positive regulation of fatty acid metabolic process 1/313 39/18722 0.48221715854327 0.61398017477399 ANXA1 1 GO:0046326 positive regulation of glucose import 1/313 39/18722 0.48221715854327 0.61398017477399 INSR 1 GO:1902742 apoptotic process involved in development 1/313 39/18722 0.48221715854327 0.61398017477399 TNFRSF1A 1 GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 1/313 39/18722 0.48221715854327 0.61398017477399 ANXA1 1 GO:0006721 terpenoid metabolic process 2/313 97/18722 0.484229380728245 0.61592424070579 RDH13/AKR1B1 2 GO:0035335 peptidyl-tyrosine dephosphorylation 2/313 97/18722 0.484229380728245 0.61592424070579 PTPRA/PGP 2 GO:0070167 regulation of biomineral tissue development 2/313 97/18722 0.484229380728245 0.61592424070579 ATP2B1/CEBPB 2 GO:0043473 pigmentation 2/313 98/18722 0.489618700409988 0.620047980939856 CD63/RAB17 2 GO:0070301 cellular response to hydrogen peroxide 2/313 98/18722 0.489618700409988 0.620047980939856 ANXA1/RHOB 2 GO:0051250 negative regulation of lymphocyte activation 3/313 157/18722 0.489730805367187 0.620047980939856 ANXA1/CEBPB/ID2 3 GO:2000377 regulation of reactive oxygen species metabolic process 3/313 157/18722 0.489730805367187 0.620047980939856 PAGE4/RHOA/STK17A 3 GO:0009069 serine family amino acid metabolic process 1/313 40/18722 0.490891677056141 0.620047980939856 SERINC5 1 GO:0009187 cyclic nucleotide metabolic process 1/313 40/18722 0.490891677056141 0.620047980939856 PDE4B 1 GO:0010863 positive regulation of phospholipase C activity 1/313 40/18722 0.490891677056141 0.620047980939856 FLT1 1 GO:0030501 positive regulation of bone mineralization 1/313 40/18722 0.490891677056141 0.620047980939856 ATP2B1 1 GO:0031111 negative regulation of microtubule polymerization or depolymerization 1/313 40/18722 0.490891677056141 0.620047980939856 STMN1 1 GO:0032094 response to food 1/313 40/18722 0.490891677056141 0.620047980939856 SLC16A1 1 GO:0032892 positive regulation of organic acid transport 1/313 40/18722 0.490891677056141 0.620047980939856 ITGB1 1 GO:0045022 early endosome to late endosome transport 1/313 40/18722 0.490891677056141 0.620047980939856 EZR 1 GO:0045740 positive regulation of DNA replication 1/313 40/18722 0.490891677056141 0.620047980939856 JUN 1 GO:0045841 negative regulation of mitotic metaphase/anaphase transition 1/313 40/18722 0.490891677056141 0.620047980939856 CCNB1 1 GO:0046365 monosaccharide catabolic process 1/313 40/18722 0.490891677056141 0.620047980939856 ENO1 1 GO:0150077 regulation of neuroinflammatory response 1/313 40/18722 0.490891677056141 0.620047980939856 CTSC 1 GO:1901223 negative regulation of NIK/NF-kappaB signaling 1/313 40/18722 0.490891677056141 0.620047980939856 TMSB4X 1 GO:1901661 quinone metabolic process 1/313 40/18722 0.490891677056141 0.620047980939856 AKR1B1 1 GO:1901998 toxin transport 1/313 40/18722 0.490891677056141 0.620047980939856 ANTXR2 1 GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell 1/313 40/18722 0.490891677056141 0.620047980939856 RHOA 1 GO:2000142 regulation of DNA-templated transcription, initiation 1/313 40/18722 0.490891677056141 0.620047980939856 JUN 1 GO:0018393 internal peptidyl-lysine acetylation 3/313 158/18722 0.493944356792606 0.623696904248574 MBD3/ISL1/MORF4L2 3 GO:0060291 long-term synaptic potentiation 2/313 99/18722 0.494972656678872 0.624374056983587 PLK2/LGMN 2 GO:0060996 dendritic spine development 2/313 99/18722 0.494972656678872 0.624374056983587 CFL1/PLK2 2 GO:0110149 regulation of biomineralization 2/313 99/18722 0.494972656678872 0.624374056983587 ATP2B1/CEBPB 2 GO:0032386 regulation of intracellular transport 6/313 337/18722 0.495769642900373 0.62517225257427 TCAF1/ICE1/OAZ1/EZR/NMT1/FERMT1 6 GO:0032200 telomere organization 3/313 159/18722 0.498140663988949 0.627076843271017 PPP1R10/PARP1/MAP3K4 3 GO:0018209 peptidyl-serine modification 6/313 338/18722 0.498642847481271 0.627076843271017 CAV1/NEK6/MIF/PARP1/PLK2/CCNB1 6 GO:0001953 negative regulation of cell-matrix adhesion 1/313 41/18722 0.499421326188002 0.627076843271017 SERPINE1 1 GO:0002251 organ or tissue specific immune response 1/313 41/18722 0.499421326188002 0.627076843271017 RAB17 1 GO:0007099 centriole replication 1/313 41/18722 0.499421326188002 0.627076843271017 PLK2 1 GO:0032735 positive regulation of interleukin-12 production 1/313 41/18722 0.499421326188002 0.627076843271017 ISL1 1 GO:0048286 lung alveolus development 1/313 41/18722 0.499421326188002 0.627076843271017 ERRFI1 1 GO:0050892 intestinal absorption 1/313 41/18722 0.499421326188002 0.627076843271017 EZR 1 GO:0051693 actin filament capping 1/313 41/18722 0.499421326188002 0.627076843271017 SCIN 1 GO:0060612 adipose tissue development 1/313 41/18722 0.499421326188002 0.627076843271017 ARRDC3 1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 1/313 41/18722 0.499421326188002 0.627076843271017 S100A10 1 GO:1905314 semi-lunar valve development 1/313 41/18722 0.499421326188002 0.627076843271017 TNFRSF1A 1 GO:1905521 regulation of macrophage migration 1/313 41/18722 0.499421326188002 0.627076843271017 MIF 1 GO:0006641 triglyceride metabolic process 2/313 100/18722 0.500290922917779 0.627547790295877 CAV1/GPX1 2 GO:0009062 fatty acid catabolic process 2/313 100/18722 0.500290922917779 0.627547790295877 CROT/SLC27A2 2 GO:0051588 regulation of neurotransmitter transport 2/313 100/18722 0.500290922917779 0.627547790295877 ITGB1/CALM1 2 GO:0006475 internal protein amino acid acetylation 3/313 160/18722 0.502319456760928 0.629884773349425 MBD3/ISL1/MORF4L2 3 GO:0051650 establishment of vesicle localization 3/313 161/18722 0.506480473111151 0.630948768583034 RAB17/PDCD6/CLN3 3 GO:0071219 cellular response to molecule of bacterial origin 4/313 221/18722 0.506821640292172 0.630948768583034 SERPINE1/RHOA/CEBPB/PDE4B 4 GO:0006470 protein dephosphorylation 5/313 281/18722 0.507041776165779 0.630948768583034 PHPT1/PTPRA/CALM1/PPP1R15A/PGP 5 GO:0098813 nuclear chromosome segregation 5/313 281/18722 0.507041776165779 0.630948768583034 NEK6/PTTG1/CDC20/TOP2A/CCNB1 5 GO:0000413 protein peptidyl-prolyl isomerization 1/313 42/18722 0.50780851771432 0.630948768583034 FKBP8 1 GO:0007212 dopamine receptor signaling pathway 1/313 42/18722 0.50780851771432 0.630948768583034 CAV2 1 GO:0009154 purine ribonucleotide catabolic process 1/313 42/18722 0.50780851771432 0.630948768583034 PDE4B 1 GO:0010677 negative regulation of cellular carbohydrate metabolic process 1/313 42/18722 0.50780851771432 0.630948768583034 PGP 1 GO:0014003 oligodendrocyte development 1/313 42/18722 0.50780851771432 0.630948768583034 CLU 1 GO:0021575 hindbrain morphogenesis 1/313 42/18722 0.50780851771432 0.630948768583034 HES1 1 GO:0021795 cerebral cortex cell migration 1/313 42/18722 0.50780851771432 0.630948768583034 RHOA 1 GO:0030574 collagen catabolic process 1/313 42/18722 0.50780851771432 0.630948768583034 ITGB1 1 GO:0030890 positive regulation of B cell proliferation 1/313 42/18722 0.50780851771432 0.630948768583034 MIF 1 GO:0032467 positive regulation of cytokinesis 1/313 42/18722 0.50780851771432 0.630948768583034 RHOA 1 GO:0032965 regulation of collagen biosynthetic process 1/313 42/18722 0.50780851771432 0.630948768583034 ERRFI1 1 GO:0042168 heme metabolic process 1/313 42/18722 0.50780851771432 0.630948768583034 BLVRA 1 GO:0043507 positive regulation of JUN kinase activity 1/313 42/18722 0.50780851771432 0.630948768583034 MAP3K4 1 GO:0045047 protein targeting to ER 1/313 42/18722 0.50780851771432 0.630948768583034 HERPUD1 1 GO:0045773 positive regulation of axon extension 1/313 42/18722 0.50780851771432 0.630948768583034 FN1 1 GO:0046596 regulation of viral entry into host cell 1/313 42/18722 0.50780851771432 0.630948768583034 LY6E 1 GO:0046688 response to copper ion 1/313 42/18722 0.50780851771432 0.630948768583034 SOD3 1 GO:0051602 response to electrical stimulus 1/313 42/18722 0.50780851771432 0.630948768583034 BTG2 1 GO:0072595 maintenance of protein localization in organelle 1/313 42/18722 0.50780851771432 0.630948768583034 GJA1 1 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis 1/313 42/18722 0.50780851771432 0.630948768583034 RHOA 1 GO:0090317 negative regulation of intracellular protein transport 1/313 42/18722 0.50780851771432 0.630948768583034 FERMT1 1 GO:1900274 regulation of phospholipase C activity 1/313 42/18722 0.50780851771432 0.630948768583034 FLT1 1 GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle 1/313 42/18722 0.50780851771432 0.630948768583034 CCNB1 1 GO:2000404 regulation of T cell migration 1/313 42/18722 0.50780851771432 0.630948768583034 RHOA 1 GO:0015931 nucleobase-containing compound transport 4/313 222/18722 0.510356720855074 0.633908005316563 YBX1/SSB/EIF5A/GJA1 4 GO:0062014 negative regulation of small molecule metabolic process 2/313 102/18722 0.510819181767421 0.634275481079116 PARP1/PGP 2 GO:0022613 ribonucleoprotein complex biogenesis 8/313 463/18722 0.512490332702637 0.63614303769121 RPS27/RPS17/RPS21/RPL38/RPS28/EIF4H/EIF4B/SCAF11 8 GO:0050657 nucleic acid transport 3/313 163/18722 0.514748168923421 0.636831039945615 YBX1/SSB/EIF5A 3 GO:0050658 RNA transport 3/313 163/18722 0.514748168923421 0.636831039945615 YBX1/SSB/EIF5A 3 GO:0014013 regulation of gliogenesis 2/313 103/18722 0.516028622297344 0.636831039945615 ID2/HES1 2 GO:0019395 fatty acid oxidation 2/313 103/18722 0.516028622297344 0.636831039945615 CROT/SLC27A2 2 GO:0030004 cellular monovalent inorganic cation homeostasis 2/313 103/18722 0.516028622297344 0.636831039945615 CLIC4/CLN3 2 GO:0001504 neurotransmitter uptake 1/313 43/18722 0.516055623386452 0.636831039945615 ITGB1 1 GO:0014014 negative regulation of gliogenesis 1/313 43/18722 0.516055623386452 0.636831039945615 HES1 1 GO:0030517 negative regulation of axon extension 1/313 43/18722 0.516055623386452 0.636831039945615 SEMA6D 1 GO:0033173 calcineurin-NFAT signaling cascade 1/313 43/18722 0.516055623386452 0.636831039945615 FHL2 1 GO:0034661 ncRNA catabolic process 1/313 43/18722 0.516055623386452 0.636831039945615 KCNQ1OT1 1 GO:0042088 T-helper 1 type immune response 1/313 43/18722 0.516055623386452 0.636831039945615 ANXA1 1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/313 43/18722 0.516055623386452 0.636831039945615 MIF 1 GO:0045494 photoreceptor cell maintenance 1/313 43/18722 0.516055623386452 0.636831039945615 SLC2A1 1 GO:0046636 negative regulation of alpha-beta T cell activation 1/313 43/18722 0.516055623386452 0.636831039945615 ANXA1 1 GO:0060443 mammary gland morphogenesis 1/313 43/18722 0.516055623386452 0.636831039945615 CAV1 1 GO:0098927 vesicle-mediated transport between endosomal compartments 1/313 43/18722 0.516055623386452 0.636831039945615 EZR 1 GO:0140353 lipid export from cell 1/313 43/18722 0.516055623386452 0.636831039945615 CYP19A1 1 GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 1/313 43/18722 0.516055623386452 0.636831039945615 HSPA1A 1 GO:0048562 embryonic organ morphogenesis 5/313 285/18722 0.519540417911827 0.640923645816696 FBN1/RPL38/MFAP5/ID2/HES1 5 GO:0006364 rRNA processing 4/313 225/18722 0.520892667568122 0.641932457233999 RPS27/RPS17/RPS21/RPS28 4 GO:0008037 cell recognition 4/313 225/18722 0.520892667568122 0.641932457233999 ALDOA/LY6K/BSG/SPESP1 4 GO:0032963 collagen metabolic process 2/313 104/18722 0.521201267483659 0.641932457233999 ITGB1/ERRFI1 2 GO:0046634 regulation of alpha-beta T cell activation 2/313 104/18722 0.521201267483659 0.641932457233999 ANXA1/RHOA 2 GO:1901890 positive regulation of cell junction assembly 2/313 104/18722 0.521201267483659 0.641932457233999 CAV1/S100A10 2 GO:0007528 neuromuscular junction development 1/313 44/18722 0.524164975593745 0.643143784485971 PPFIBP1 1 GO:0008542 visual learning 1/313 44/18722 0.524164975593745 0.643143784485971 ITGB1 1 GO:0032007 negative regulation of TOR signaling 1/313 44/18722 0.524164975593745 0.643143784485971 PDCD6 1 GO:0032620 interleukin-17 production 1/313 44/18722 0.524164975593745 0.643143784485971 SLC7A5 1 GO:0032660 regulation of interleukin-17 production 1/313 44/18722 0.524164975593745 0.643143784485971 SLC7A5 1 GO:0042269 regulation of natural killer cell mediated cytotoxicity 1/313 44/18722 0.524164975593745 0.643143784485971 SERPINB9 1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 1/313 44/18722 0.524164975593745 0.643143784485971 RHOA 1 GO:0046006 regulation of activated T cell proliferation 1/313 44/18722 0.524164975593745 0.643143784485971 IGF2 1 GO:0048066 developmental pigmentation 1/313 44/18722 0.524164975593745 0.643143784485971 CD63 1 GO:0048806 genitalia development 1/313 44/18722 0.524164975593745 0.643143784485971 DHCR24 1 GO:0060711 labyrinthine layer development 1/313 44/18722 0.524164975593745 0.643143784485971 HES1 1 GO:0006486 protein glycosylation 4/313 226/18722 0.524380957983833 0.643143784485971 GALNT11/VEGFB/EXTL2/B3GNT2 4 GO:0043413 macromolecule glycosylation 4/313 226/18722 0.524380957983833 0.643143784485971 GALNT11/VEGFB/EXTL2/B3GNT2 4 GO:0000041 transition metal ion transport 2/313 105/18722 0.526336888406042 0.644919386598585 FTL/FTH1 2 GO:0062207 regulation of pattern recognition receptor signaling pathway 2/313 105/18722 0.526336888406042 0.644919386598585 CAV1/HSPA1A 2 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 2/313 105/18722 0.526336888406042 0.644919386598585 EPS8L1/PFN1 2 GO:0051236 establishment of RNA localization 3/313 166/18722 0.527010299379085 0.645377757379123 YBX1/SSB/EIF5A 3 GO:0043087 regulation of GTPase activity 6/313 348/18722 0.52705002566107 0.645377757379123 STMN3/CAV2/ITGB1/S100A10/STMN1/IQGAP2 6 GO:0055088 lipid homeostasis 3/313 167/18722 0.531059601221957 0.647444126088871 CAV1/ABHD8/ORMDL1 3 GO:2000278 regulation of DNA biosynthetic process 2/313 106/18722 0.53143527400251 0.647444126088871 GJA1/MAP3K4 2 GO:0003197 endocardial cushion development 1/313 45/18722 0.53213886801473 0.647444126088871 ISL1 1 GO:0003254 regulation of membrane depolarization 1/313 45/18722 0.53213886801473 0.647444126088871 PARP1 1 GO:0006903 vesicle targeting 1/313 45/18722 0.53213886801473 0.647444126088871 PDCD6 1 GO:0010824 regulation of centrosome duplication 1/313 45/18722 0.53213886801473 0.647444126088871 PLK2 1 GO:0022602 ovulation cycle process 1/313 45/18722 0.53213886801473 0.647444126088871 ADAMTS1 1 GO:0030835 negative regulation of actin filament depolymerization 1/313 45/18722 0.53213886801473 0.647444126088871 SCIN 1 GO:0030850 prostate gland development 1/313 45/18722 0.53213886801473 0.647444126088871 ANXA1 1 GO:0031670 cellular response to nutrient 1/313 45/18722 0.53213886801473 0.647444126088871 ATP2B1 1 GO:0032309 icosanoid secretion 1/313 45/18722 0.53213886801473 0.647444126088871 ANXA1 1 GO:0035305 negative regulation of dephosphorylation 1/313 45/18722 0.53213886801473 0.647444126088871 PPP1R15A 1 GO:0035987 endodermal cell differentiation 1/313 45/18722 0.53213886801473 0.647444126088871 FN1 1 GO:0048546 digestive tract morphogenesis 1/313 45/18722 0.53213886801473 0.647444126088871 ID2 1 GO:0048599 oocyte development 1/313 45/18722 0.53213886801473 0.647444126088871 CCNB1 1 GO:0051180 vitamin transport 1/313 45/18722 0.53213886801473 0.647444126088871 SLC2A1 1 GO:0060119 inner ear receptor cell development 1/313 45/18722 0.53213886801473 0.647444126088871 HES1 1 GO:0071364 cellular response to epidermal growth factor stimulus 1/313 45/18722 0.53213886801473 0.647444126088871 ERRFI1 1 GO:0098534 centriole assembly 1/313 45/18722 0.53213886801473 0.647444126088871 PLK2 1 GO:2000273 positive regulation of signaling receptor activity 1/313 45/18722 0.53213886801473 0.647444126088871 ITGB1 1 GO:0071103 DNA conformation change 5/313 290/18722 0.534973124162002 0.650666183391264 HMGB3/ANXA1/TOP2A/CCNB1/BRD2 5 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 7/313 412/18722 0.536075653357242 0.650666183391264 CAV1/DDA1/HERPUD1/HSPA1A/CDC20/CLU/PLK2 7 GO:0000018 regulation of DNA recombination 2/313 107/18722 0.536496230539842 0.650666183391264 FUS/PARP1 2 GO:0021761 limbic system development 2/313 107/18722 0.536496230539842 0.650666183391264 NRP2/BTG2 2 GO:0036503 ERAD pathway 2/313 107/18722 0.536496230539842 0.650666183391264 CAV1/HERPUD1 2 GO:0042303 molting cycle 2/313 107/18722 0.536496230539842 0.650666183391264 LGR5/FERMT1 2 GO:0042633 hair cycle 2/313 107/18722 0.536496230539842 0.650666183391264 LGR5/FERMT1 2 GO:0051341 regulation of oxidoreductase activity 2/313 107/18722 0.536496230539842 0.650666183391264 CAV1/CALM1 2 GO:0071868 cellular response to monoamine stimulus 2/313 107/18722 0.536496230539842 0.650666183391264 CAV2/PDE4B 2 GO:0071870 cellular response to catecholamine stimulus 2/313 107/18722 0.536496230539842 0.650666183391264 CAV2/PDE4B 2 GO:0016236 macroautophagy 5/313 291/18722 0.538032940596865 0.652322103456135 GAPDH/UBA5/CALM1/CLN3/EXOC1 5 GO:0001974 blood vessel remodeling 1/313 46/18722 0.539979556257563 0.652603863705569 TMBIM1 1 GO:0006195 purine nucleotide catabolic process 1/313 46/18722 0.539979556257563 0.652603863705569 PDE4B 1 GO:0006383 transcription by RNA polymerase III 1/313 46/18722 0.539979556257563 0.652603863705569 ICE1 1 GO:0006984 ER-nucleus signaling pathway 1/313 46/18722 0.539979556257563 0.652603863705569 PPP1R15A 1 GO:0010828 positive regulation of glucose transmembrane transport 1/313 46/18722 0.539979556257563 0.652603863705569 INSR 1 GO:0010830 regulation of myotube differentiation 1/313 46/18722 0.539979556257563 0.652603863705569 BHLHE41 1 GO:0043616 keratinocyte proliferation 1/313 46/18722 0.539979556257563 0.652603863705569 FERMT1 1 GO:0061462 protein localization to lysosome 1/313 46/18722 0.539979556257563 0.652603863705569 CLU 1 GO:0072599 establishment of protein localization to endoplasmic reticulum 1/313 46/18722 0.539979556257563 0.652603863705569 HERPUD1 1 GO:1900271 regulation of long-term synaptic potentiation 1/313 46/18722 0.539979556257563 0.652603863705569 LGMN 1 GO:0002832 negative regulation of response to biotic stimulus 2/313 108/18722 0.54151958109663 0.653842386690412 HTRA1/SERPINB9 2 GO:0033138 positive regulation of peptidyl-serine phosphorylation 2/313 108/18722 0.54151958109663 0.653842386690412 CAV1/MIF 2 GO:0034440 lipid oxidation 2/313 108/18722 0.54151958109663 0.653842386690412 CROT/SLC27A2 2 GO:0072009 nephron epithelium development 2/313 109/18722 0.546505165058664 0.656916511364556 MAGED1/HES1 2 GO:0048469 cell maturation 3/313 171/18722 0.547060946874207 0.656916511364556 AKR1B1/CCNB1/HES1 3 GO:0051048 negative regulation of secretion 3/313 171/18722 0.547060946874207 0.656916511364556 ANXA1/TNFRSF1A/GJA1 3 GO:0010948 negative regulation of cell cycle process 5/313 294/18722 0.547156713085171 0.656916511364556 SOX4/PTTG1/PPP1R10/PLK2/CCNB1 5 GO:0001754 eye photoreceptor cell differentiation 1/313 47/18722 0.547689258489914 0.656916511364556 RDH13 1 GO:0006998 nuclear envelope organization 1/313 47/18722 0.547689258489914 0.656916511364556 NEK6 1 GO:0007595 lactation 1/313 47/18722 0.547689258489914 0.656916511364556 CAV1 1 GO:0009261 ribonucleotide catabolic process 1/313 47/18722 0.547689258489914 0.656916511364556 PDE4B 1 GO:0010799 regulation of peptidyl-threonine phosphorylation 1/313 47/18722 0.547689258489914 0.656916511364556 CALM1 1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 1/313 47/18722 0.547689258489914 0.656916511364556 HSPA1A 1 GO:0019884 antigen processing and presentation of exogenous antigen 1/313 47/18722 0.547689258489914 0.656916511364556 LGMN 1 GO:0031641 regulation of myelination 1/313 47/18722 0.547689258489914 0.656916511364556 CTSC 1 GO:0045581 negative regulation of T cell differentiation 1/313 47/18722 0.547689258489914 0.656916511364556 ANXA1 1 GO:0045601 regulation of endothelial cell differentiation 1/313 47/18722 0.547689258489914 0.656916511364556 TNFRSF1A 1 GO:0046677 response to antibiotic 1/313 47/18722 0.547689258489914 0.656916511364556 RPL23 1 GO:0047496 vesicle transport along microtubule 1/313 47/18722 0.547689258489914 0.656916511364556 CLN3 1 GO:0050798 activated T cell proliferation 1/313 47/18722 0.547689258489914 0.656916511364556 IGF2 1 GO:0050885 neuromuscular process controlling balance 1/313 47/18722 0.547689258489914 0.656916511364556 CLN3 1 GO:0051972 regulation of telomerase activity 1/313 47/18722 0.547689258489914 0.656916511364556 MAP3K4 1 GO:0061001 regulation of dendritic spine morphogenesis 1/313 47/18722 0.547689258489914 0.656916511364556 CFL1 1 GO:0120163 negative regulation of cold-induced thermogenesis 1/313 47/18722 0.547689258489914 0.656916511364556 ARRDC3 1 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 4/313 233/18722 0.548450231327119 0.657622056901525 PDE4B/LGR5/ARRDC3/RGS2 4 GO:0018958 phenol-containing compound metabolic process 2/313 110/18722 0.55145283762641 0.660598160114457 LY6E/AKR1B1 2 GO:0061387 regulation of extent of cell growth 2/313 110/18722 0.55145283762641 0.660598160114457 FN1/SEMA6D 2 GO:1904659 glucose transmembrane transport 2/313 110/18722 0.55145283762641 0.660598160114457 INSR/SLC2A1 2 GO:0060560 developmental growth involved in morphogenesis 4/313 234/18722 0.55183701882729 0.66085043431126 FN1/NRP2/SEMA6D/ITGB1 4 GO:0002686 negative regulation of leukocyte migration 1/313 48/18722 0.555270156058463 0.662876602105541 MIF 1 GO:0002715 regulation of natural killer cell mediated immunity 1/313 48/18722 0.555270156058463 0.662876602105541 SERPINB9 1 GO:0006111 regulation of gluconeogenesis 1/313 48/18722 0.555270156058463 0.662876602105541 PGP 1 GO:0032527 protein exit from endoplasmic reticulum 1/313 48/18722 0.555270156058463 0.662876602105541 HERPUD1 1 GO:0045839 negative regulation of mitotic nuclear division 1/313 48/18722 0.555270156058463 0.662876602105541 CCNB1 1 GO:0045912 negative regulation of carbohydrate metabolic process 1/313 48/18722 0.555270156058463 0.662876602105541 PGP 1 GO:0097720 calcineurin-mediated signaling 1/313 48/18722 0.555270156058463 0.662876602105541 FHL2 1 GO:1902003 regulation of amyloid-beta formation 1/313 48/18722 0.555270156058463 0.662876602105541 CLU 1 GO:1903053 regulation of extracellular matrix organization 1/313 48/18722 0.555270156058463 0.662876602105541 TNFRSF1A 1 GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 1/313 48/18722 0.555270156058463 0.662876602105541 RPL23 1 GO:0006805 xenobiotic metabolic process 2/313 111/18722 0.556362469334303 0.663556366151532 CYP2J2/GSTO1 2 GO:0071867 response to monoamine 2/313 111/18722 0.556362469334303 0.663556366151532 CAV2/PDE4B 2 GO:0071869 response to catecholamine 2/313 111/18722 0.556362469334303 0.663556366151532 CAV2/PDE4B 2 GO:0051052 regulation of DNA metabolic process 6/313 359/18722 0.557524099646417 0.664733556953934 MBD3/FUS/PPP1R10/PARP1/GJA1/MAP3K4 6 GO:0016072 rRNA metabolic process 4/313 236/18722 0.558570389422503 0.665326543585304 RPS27/RPS17/RPS21/RPS28 4 GO:0002526 acute inflammatory response 2/313 112/18722 0.561233945581607 0.665326543585304 FN1/CEBPB 2 GO:0046632 alpha-beta T cell differentiation 2/313 112/18722 0.561233945581607 0.665326543585304 ANXA1/RHOA 2 GO:0042254 ribosome biogenesis 5/313 299/18722 0.562170463611087 0.665326543585304 RPS27/RPS17/RPS21/RPL38/RPS28 5 GO:0001913 T cell mediated cytotoxicity 1/313 49/18722 0.562724394098182 0.665326543585304 CTSC 1 GO:0002762 negative regulation of myeloid leukocyte differentiation 1/313 49/18722 0.562724394098182 0.665326543585304 FBN1 1 GO:0006778 porphyrin-containing compound metabolic process 1/313 49/18722 0.562724394098182 0.665326543585304 BLVRA 1 GO:0007602 phototransduction 1/313 49/18722 0.562724394098182 0.665326543585304 NMT1 1 GO:0008038 neuron recognition 1/313 49/18722 0.562724394098182 0.665326543585304 BSG 1 GO:0008206 bile acid metabolic process 1/313 49/18722 0.562724394098182 0.665326543585304 SLC27A2 1 GO:0018198 peptidyl-cysteine modification 1/313 49/18722 0.562724394098182 0.665326543585304 GAPDH 1 GO:0030195 negative regulation of blood coagulation 1/313 49/18722 0.562724394098182 0.665326543585304 SERPINE1 1 GO:0042304 regulation of fatty acid biosynthetic process 1/313 49/18722 0.562724394098182 0.665326543585304 ANXA1 1 GO:0042461 photoreceptor cell development 1/313 49/18722 0.562724394098182 0.665326543585304 RDH13 1 GO:0043330 response to exogenous dsRNA 1/313 49/18722 0.562724394098182 0.665326543585304 CAV1 1 GO:0043457 regulation of cellular respiration 1/313 49/18722 0.562724394098182 0.665326543585304 RHOA 1 GO:0045778 positive regulation of ossification 1/313 49/18722 0.562724394098182 0.665326543585304 ATP2B1 1 GO:0046605 regulation of centrosome cycle 1/313 49/18722 0.562724394098182 0.665326543585304 PLK2 1 GO:0048168 regulation of neuronal synaptic plasticity 1/313 49/18722 0.562724394098182 0.665326543585304 CLN3 1 GO:0051445 regulation of meiotic cell cycle 1/313 49/18722 0.562724394098182 0.665326543585304 CDC20 1 GO:0051932 synaptic transmission, GABAergic 1/313 49/18722 0.562724394098182 0.665326543585304 CLN3 1 GO:0060986 endocrine hormone secretion 1/313 49/18722 0.562724394098182 0.665326543585304 GJA1 1 GO:0070849 response to epidermal growth factor 1/313 49/18722 0.562724394098182 0.665326543585304 ERRFI1 1 GO:0072666 establishment of protein localization to vacuole 1/313 49/18722 0.562724394098182 0.665326543585304 CLU 1 GO:0086009 membrane repolarization 1/313 49/18722 0.562724394098182 0.665326543585304 CAV1 1 GO:0048771 tissue remodeling 3/313 175/18722 0.562740076266004 0.665326543585304 CAV1/TMBIM1/GJA1 3 GO:0050954 sensory perception of mechanical stimulus 3/313 175/18722 0.562740076266004 0.665326543585304 RPL38/GPX1/BIRC5 3 GO:0051259 protein complex oligomerization 4/313 238/18722 0.565249264938734 0.668085672655002 ALDOA/MIF/FUS/PRMT1 4 GO:0071347 cellular response to interleukin-1 2/313 113/18722 0.566067166174591 0.668844724278916 CEBPB/EGR1 2 GO:0006913 nucleocytoplasmic transport 5/313 301/18722 0.568106017650498 0.670227267039793 RPL23/PTTG1IP/PPP1R10/SSB/FERMT1 5 GO:0051169 nuclear transport 5/313 301/18722 0.568106017650498 0.670227267039793 RPL23/PTTG1IP/PPP1R10/SSB/FERMT1 5 GO:0001961 positive regulation of cytokine-mediated signaling pathway 1/313 50/18722 0.57005408213156 0.670227267039793 HSPA1A 1 GO:0002448 mast cell mediated immunity 1/313 50/18722 0.57005408213156 0.670227267039793 SERPINB9 1 GO:0007080 mitotic metaphase plate congression 1/313 50/18722 0.57005408213156 0.670227267039793 CCNB1 1 GO:0008089 anterograde axonal transport 1/313 50/18722 0.57005408213156 0.670227267039793 HSPB1 1 GO:0010665 regulation of cardiac muscle cell apoptotic process 1/313 50/18722 0.57005408213156 0.670227267039793 PPP1R10 1 GO:0019083 viral transcription 1/313 50/18722 0.57005408213156 0.670227267039793 JUN 1 GO:0045058 T cell selection 1/313 50/18722 0.57005408213156 0.670227267039793 RHOA 1 GO:0051646 mitochondrion localization 1/313 50/18722 0.57005408213156 0.670227267039793 ARMCX3 1 GO:0060688 regulation of morphogenesis of a branching structure 1/313 50/18722 0.57005408213156 0.670227267039793 MAGED1 1 GO:0090102 cochlea development 1/313 50/18722 0.57005408213156 0.670227267039793 HES1 1 GO:1900047 negative regulation of hemostasis 1/313 50/18722 0.57005408213156 0.670227267039793 SERPINE1 1 GO:1901570 fatty acid derivative biosynthetic process 1/313 50/18722 0.57005408213156 0.670227267039793 TECR 1 GO:1903747 regulation of establishment of protein localization to mitochondrion 1/313 50/18722 0.57005408213156 0.670227267039793 NMT1 1 GO:1904036 negative regulation of epithelial cell apoptotic process 1/313 50/18722 0.57005408213156 0.670227267039793 SERPINE1 1 GO:0051648 vesicle localization 3/313 177/18722 0.570455508207326 0.670285222143609 RAB17/PDCD6/CLN3 3 GO:0071466 cellular response to xenobiotic stimulus 3/313 177/18722 0.570455508207326 0.670285222143609 CYP2J2/GSTO1/PDE4B 3 GO:0008645 hexose transmembrane transport 2/313 114/18722 0.570862044879777 0.670391186025831 INSR/SLC2A1 2 GO:0051056 regulation of small GTPase mediated signal transduction 5/313 302/18722 0.571058391987067 0.670391186025831 EPS8L1/STMN3/TIMP2/ITGB1/STMN1 5 GO:0032259 methylation 6/313 364/18722 0.571073973281264 0.670391186025831 MBD3/FOS/PRMT1/PARP1/BTG2/DNMT3A 6 GO:0070085 glycosylation 4/313 240/18722 0.571872628673708 0.671121793267819 GALNT11/VEGFB/EXTL2/B3GNT2 4 GO:0006813 potassium ion transport 4/313 241/18722 0.575163191410826 0.674120781829089 CAV1/FXYD3/CD63/ITGB1 4 GO:0043279 response to alkaloid 2/313 115/18722 0.575618508988012 0.674120781829089 FOSB/DNMT3A 2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone 1/313 51/18722 0.577261294657953 0.674120781829089 NDUFB1 1 GO:0009584 detection of visible light 1/313 51/18722 0.577261294657953 0.674120781829089 NMT1 1 GO:0009948 anterior/posterior axis specification 1/313 51/18722 0.577261294657953 0.674120781829089 WLS 1 GO:0010656 negative regulation of muscle cell apoptotic process 1/313 51/18722 0.577261294657953 0.674120781829089 PPP1R10 1 GO:0010874 regulation of cholesterol efflux 1/313 51/18722 0.577261294657953 0.674120781829089 CAV1 1 GO:0032873 negative regulation of stress-activated MAPK cascade 1/313 51/18722 0.577261294657953 0.674120781829089 EZR 1 GO:0032964 collagen biosynthetic process 1/313 51/18722 0.577261294657953 0.674120781829089 ERRFI1 1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 1/313 51/18722 0.577261294657953 0.674120781829089 RHOA 1 GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 1/313 51/18722 0.577261294657953 0.674120781829089 ANXA1 1 GO:0045661 regulation of myoblast differentiation 1/313 51/18722 0.577261294657953 0.674120781829089 IGFBP3 1 GO:0048013 ephrin receptor signaling pathway 1/313 51/18722 0.577261294657953 0.674120781829089 EFNB1 1 GO:0060632 regulation of microtubule-based movement 1/313 51/18722 0.577261294657953 0.674120781829089 CCSAP 1 GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 1/313 51/18722 0.577261294657953 0.674120781829089 EZR 1 GO:0071622 regulation of granulocyte chemotaxis 1/313 51/18722 0.577261294657953 0.674120781829089 JAM3 1 GO:1901991 negative regulation of mitotic cell cycle phase transition 3/313 179/18722 0.578086636896036 0.674877591739714 SOX4/PLK2/CCNB1 3 GO:0006720 isoprenoid metabolic process 2/313 116/18722 0.580336498889139 0.676881449531542 RDH13/AKR1B1 2 GO:0015749 monosaccharide transmembrane transport 2/313 116/18722 0.580336498889139 0.676881449531542 INSR/SLC2A1 2 GO:0021782 glial cell development 2/313 116/18722 0.580336498889139 0.676881449531542 SOX4/CLU 2 GO:0010662 regulation of striated muscle cell apoptotic process 1/313 52/18722 0.584348071733207 0.68010183707989 PPP1R10 1 GO:0010718 positive regulation of epithelial to mesenchymal transition 1/313 52/18722 0.584348071733207 0.68010183707989 ISL1 1 GO:0035196 production of miRNAs involved in gene silencing by miRNA 1/313 52/18722 0.584348071733207 0.68010183707989 DDX5 1 GO:0043277 apoptotic cell clearance 1/313 52/18722 0.584348071733207 0.68010183707989 ANXA1 1 GO:0060071 Wnt signaling pathway, planar cell polarity pathway 1/313 52/18722 0.584348071733207 0.68010183707989 RHOA 1 GO:0072132 mesenchyme morphogenesis 1/313 52/18722 0.584348071733207 0.68010183707989 ISL1 1 GO:0072523 purine-containing compound catabolic process 1/313 52/18722 0.584348071733207 0.68010183707989 PDE4B 1 GO:0030301 cholesterol transport 2/313 117/18722 0.58501596765703 0.680463119117114 CAV1/CLU 2 GO:0072676 lymphocyte migration 2/313 117/18722 0.58501596765703 0.680463119117114 CD99/RHOA 2 GO:0099504 synaptic vesicle cycle 3/313 181/18722 0.585632428487305 0.680972099954541 ACTG1/CALM1/ACTB 3 GO:0017148 negative regulation of translation 4/313 245/18722 0.58818200979588 0.683727911845165 GAPDH/YBX1/BTG2/RGS2 4 GO:0022612 gland morphogenesis 2/313 118/18722 0.58965688064476 0.684815053268639 CAV1/CEBPB 2 GO:0030203 glycosaminoglycan metabolic process 2/313 118/18722 0.58965688064476 0.684815053268639 ITIH5/B3GNT2 2 GO:0034219 carbohydrate transmembrane transport 2/313 118/18722 0.58965688064476 0.684815053268639 INSR/SLC2A1 2 GO:0001541 ovarian follicle development 1/313 53/18722 0.591316419539715 0.685167692346081 CEBPB 1 GO:0002707 negative regulation of lymphocyte mediated immunity 1/313 53/18722 0.591316419539715 0.685167692346081 SERPINB9 1 GO:0032210 regulation of telomere maintenance via telomerase 1/313 53/18722 0.591316419539715 0.685167692346081 MAP3K4 1 GO:0045806 negative regulation of endocytosis 1/313 53/18722 0.591316419539715 0.685167692346081 CAV1 1 GO:0050819 negative regulation of coagulation 1/313 53/18722 0.591316419539715 0.685167692346081 SERPINE1 1 GO:0071320 cellular response to cAMP 1/313 53/18722 0.591316419539715 0.685167692346081 EZR 1 GO:0071715 icosanoid transport 1/313 53/18722 0.591316419539715 0.685167692346081 ANXA1 1 GO:0071216 cellular response to biotic stimulus 4/313 246/18722 0.591400324940694 0.685167692346081 SERPINE1/RHOA/CEBPB/PDE4B 4 GO:0001706 endoderm formation 1/313 54/18722 0.598168310947079 0.690696621102678 FN1 1 GO:0006968 cellular defense response 1/313 54/18722 0.598168310947079 0.690696621102678 ITGB1 1 GO:0007215 glutamate receptor signaling pathway 1/313 54/18722 0.598168310947079 0.690696621102678 CLN3 1 GO:0010659 cardiac muscle cell apoptotic process 1/313 54/18722 0.598168310947079 0.690696621102678 PPP1R10 1 GO:0014888 striated muscle adaptation 1/313 54/18722 0.598168310947079 0.690696621102678 ERRFI1 1 GO:0030834 regulation of actin filament depolymerization 1/313 54/18722 0.598168310947079 0.690696621102678 SCIN 1 GO:0031050 dsRNA processing 1/313 54/18722 0.598168310947079 0.690696621102678 DDX5 1 GO:0032330 regulation of chondrocyte differentiation 1/313 54/18722 0.598168310947079 0.690696621102678 SCIN 1 GO:0035065 regulation of histone acetylation 1/313 54/18722 0.598168310947079 0.690696621102678 ISL1 1 GO:0070918 production of small RNA involved in gene silencing by RNA 1/313 54/18722 0.598168310947079 0.690696621102678 DDX5 1 GO:2000300 regulation of synaptic vesicle exocytosis 1/313 54/18722 0.598168310947079 0.690696621102678 CALM1 1 GO:0048593 camera-type eye morphogenesis 2/313 120/18722 0.598822959728256 0.69082394172287 RDH13/C12orf57 2 GO:0071901 negative regulation of protein serine/threonine kinase activity 2/313 120/18722 0.598822959728256 0.69082394172287 CAV1/RGS2 2 GO:0072655 establishment of protein localization to mitochondrion 2/313 120/18722 0.598822959728256 0.69082394172287 CALM1/NMT1 2 GO:0140013 meiotic nuclear division 3/313 185/18722 0.600464351026789 0.692507659605872 PTTG1/CDC20/TOP2A 3 GO:1901988 negative regulation of cell cycle phase transition 4/313 249/18722 0.600966355394026 0.692876715622367 SOX4/PPP1R10/PLK2/CCNB1 4 GO:0018205 peptidyl-lysine modification 6/313 376/18722 0.602743660016276 0.69468354354262 MBD3/ISL1/SOX4/MORF4L2/HMG20B/EGR1 6 GO:0038127 ERBB signaling pathway 2/313 121/18722 0.603348114420254 0.69468354354262 ERRFI1/LGMN 2 GO:0050804 modulation of chemical synaptic transmission 7/313 439/18722 0.603360399144586 0.69468354354262 ITGB1/PTPRA/CALM1/CLN3/CDC20/PLK2/LGMN 7 GO:0002067 glandular epithelial cell differentiation 1/313 55/18722 0.604905686063511 0.69468354354262 HES1 1 GO:0003179 heart valve morphogenesis 1/313 55/18722 0.604905686063511 0.69468354354262 SOX4 1 GO:0006414 translational elongation 1/313 55/18722 0.604905686063511 0.69468354354262 EIF5A 1 GO:0008333 endosome to lysosome transport 1/313 55/18722 0.604905686063511 0.69468354354262 RHOB 1 GO:0042220 response to cocaine 1/313 55/18722 0.604905686063511 0.69468354354262 DNMT3A 1 GO:0046164 alcohol catabolic process 1/313 55/18722 0.604905686063511 0.69468354354262 TPI1 1 GO:0048016 inositol phosphate-mediated signaling 1/313 55/18722 0.604905686063511 0.69468354354262 FHL2 1 GO:0051898 negative regulation of protein kinase B signaling 1/313 55/18722 0.604905686063511 0.69468354354262 PDCD6 1 GO:1902991 regulation of amyloid precursor protein catabolic process 1/313 55/18722 0.604905686063511 0.69468354354262 CLU 1 GO:1905517 macrophage migration 1/313 55/18722 0.604905686063511 0.69468354354262 MIF 1 GO:0099177 regulation of trans-synaptic signaling 7/313 440/18722 0.60575522849654 0.695449383258845 ITGB1/PTPRA/CALM1/CLN3/CDC20/PLK2/LGMN 7 GO:0002695 negative regulation of leukocyte activation 3/313 187/18722 0.607748890659813 0.697205984935681 ANXA1/CEBPB/ID2 3 GO:0050868 negative regulation of T cell activation 2/313 122/18722 0.607834689782382 0.697205984935681 ANXA1/CEBPB 2 GO:0072329 monocarboxylic acid catabolic process 2/313 122/18722 0.607834689782382 0.697205984935681 CROT/SLC27A2 2 GO:0018105 peptidyl-serine phosphorylation 5/313 315/18722 0.608460062601086 0.697713089856125 CAV1/NEK6/MIF/PLK2/CCNB1 5 GO:0061448 connective tissue development 4/313 252/18722 0.610397126788236 0.698498779995922 SCIN/ITGB8/ARRDC3/EGR1 4 GO:0048839 inner ear development 3/313 188/18722 0.611358001189829 0.698498779995922 LGR5/MCOLN3/HES1 3 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1/313 56/18722 0.611530452778148 0.698498779995922 BTG2 1 GO:0001658 branching involved in ureteric bud morphogenesis 1/313 56/18722 0.611530452778148 0.698498779995922 MAGED1 1 GO:0006687 glycosphingolipid metabolic process 1/313 56/18722 0.611530452778148 0.698498779995922 ITGB8 1 GO:0010518 positive regulation of phospholipase activity 1/313 56/18722 0.611530452778148 0.698498779995922 FLT1 1 GO:0010658 striated muscle cell apoptotic process 1/313 56/18722 0.611530452778148 0.698498779995922 PPP1R10 1 GO:0022029 telencephalon cell migration 1/313 56/18722 0.611530452778148 0.698498779995922 RHOA 1 GO:0030166 proteoglycan biosynthetic process 1/313 56/18722 0.611530452778148 0.698498779995922 EXTL2 1 GO:0042733 embryonic digit morphogenesis 1/313 56/18722 0.611530452778148 0.698498779995922 TMEM107 1 GO:0051784 negative regulation of nuclear division 1/313 56/18722 0.611530452778148 0.698498779995922 CCNB1 1 GO:0090175 regulation of establishment of planar polarity 1/313 56/18722 0.611530452778148 0.698498779995922 RHOA 1 GO:0098781 ncRNA transcription 1/313 56/18722 0.611530452778148 0.698498779995922 ICE1 1 GO:0071482 cellular response to light stimulus 2/313 123/18722 0.61228270683088 0.699148249821584 PARP1/NMT1 2 GO:0009101 glycoprotein biosynthetic process 5/313 317/18722 0.614046135148653 0.700741497755073 GALNT11/ITM2B/VEGFB/EXTL2/B3GNT2 5 GO:0010506 regulation of autophagy 5/313 317/18722 0.614046135148653 0.700741497755073 GAPDH/HSPB1/CLN3/PLK2/EXOC1 5 GO:0006839 mitochondrial transport 4/313 254/18722 0.616608060671116 0.702418543267391 PMAIP1/HSPA1A/MPC2/NMT1 4 GO:0007368 determination of left/right symmetry 2/313 124/18722 0.616692196633039 0.702418543267391 GALNT11/TMEM107 2 GO:0006695 cholesterol biosynthetic process 1/313 57/18722 0.618044487294404 0.702418543267391 DHCR24 1 GO:0010257 NADH dehydrogenase complex assembly 1/313 57/18722 0.618044487294404 0.702418543267391 NDUFB1 1 GO:0032981 mitochondrial respiratory chain complex I assembly 1/313 57/18722 0.618044487294404 0.702418543267391 NDUFB1 1 GO:0034205 amyloid-beta formation 1/313 57/18722 0.618044487294404 0.702418543267391 CLU 1 GO:0051155 positive regulation of striated muscle cell differentiation 1/313 57/18722 0.618044487294404 0.702418543267391 MORF4L2 1 GO:0051205 protein insertion into membrane 1/313 57/18722 0.618044487294404 0.702418543267391 NMT1 1 GO:0051289 protein homotetramerization 1/313 57/18722 0.618044487294404 0.702418543267391 ALDOA 1 GO:0060042 retina morphogenesis in camera-type eye 1/313 57/18722 0.618044487294404 0.702418543267391 RDH13 1 GO:0060760 positive regulation of response to cytokine stimulus 1/313 57/18722 0.618044487294404 0.702418543267391 HSPA1A 1 GO:0061005 cell differentiation involved in kidney development 1/313 57/18722 0.618044487294404 0.702418543267391 HES1 1 GO:1902653 secondary alcohol biosynthetic process 1/313 57/18722 0.618044487294404 0.702418543267391 DHCR24 1 GO:0007018 microtubule-based movement 6/313 382/18722 0.618098796938734 0.702418543267391 ARMCX3/CCSAP/DST/DYNLRB1/HSPB1/CLN3 6 GO:0006338 chromatin remodeling 4/313 255/18722 0.619690426129415 0.704017144814886 MBD3/SMARCA1/ACTB/BRD2 4 GO:0018210 peptidyl-threonine modification 2/313 125/18722 0.621063199967385 0.704735499933185 GALNT11/CALM1 2 GO:0051053 negative regulation of DNA metabolic process 2/313 125/18722 0.621063199967385 0.704735499933185 PARP1/GJA1 2 GO:0070585 protein localization to mitochondrion 2/313 125/18722 0.621063199967385 0.704735499933185 CALM1/NMT1 2 GO:2000027 regulation of animal organ morphogenesis 2/313 125/18722 0.621063199967385 0.704735499933185 MAGED1/RHOA 2 GO:0016042 lipid catabolic process 5/313 320/18722 0.622337937477547 0.70597155184059 CROT/CYP19A1/IDH1/SLC27A2/PRDX6 5 GO:0007131 reciprocal meiotic recombination 1/313 58/18722 0.624449634654535 0.706262554702857 TOP2A 1 GO:0010043 response to zinc ion 1/313 58/18722 0.624449634654535 0.706262554702857 PARP1 1 GO:0010559 regulation of glycoprotein biosynthetic process 1/313 58/18722 0.624449634654535 0.706262554702857 ITM2B 1 GO:0010574 regulation of vascular endothelial growth factor production 1/313 58/18722 0.624449634654535 0.706262554702857 ISL1 1 GO:0032387 negative regulation of intracellular transport 1/313 58/18722 0.624449634654535 0.706262554702857 FERMT1 1 GO:0032481 positive regulation of type I interferon production 1/313 58/18722 0.624449634654535 0.706262554702857 GAPDH 1 GO:0043506 regulation of JUN kinase activity 1/313 58/18722 0.624449634654535 0.706262554702857 MAP3K4 1 GO:0050432 catecholamine secretion 1/313 58/18722 0.624449634654535 0.706262554702857 LY6E 1 GO:0140527 reciprocal homologous recombination 1/313 58/18722 0.624449634654535 0.706262554702857 TOP2A 1 GO:2000649 regulation of sodium ion transmembrane transporter activity 1/313 58/18722 0.624449634654535 0.706262554702857 FXYD3 1 GO:0030217 T cell differentiation 4/313 257/18722 0.62580860521674 0.707589355527213 ANXA1/SOX4/RHOA/EGR1 4 GO:0051224 negative regulation of protein transport 2/313 127/18722 0.629689956923328 0.711483416040248 ANXA1/FERMT1 2 GO:0021885 forebrain cell migration 1/313 59/18722 0.630747709255539 0.711483416040248 RHOA 1 GO:0033013 tetrapyrrole metabolic process 1/313 59/18722 0.630747709255539 0.711483416040248 BLVRA 1 GO:0043551 regulation of phosphatidylinositol 3-kinase activity 1/313 59/18722 0.630747709255539 0.711483416040248 FLT1 1 GO:0046324 regulation of glucose import 1/313 59/18722 0.630747709255539 0.711483416040248 INSR 1 GO:0051055 negative regulation of lipid biosynthetic process 1/313 59/18722 0.630747709255539 0.711483416040248 ORMDL1 1 GO:0051353 positive regulation of oxidoreductase activity 1/313 59/18722 0.630747709255539 0.711483416040248 CALM1 1 GO:2000351 regulation of endothelial cell apoptotic process 1/313 59/18722 0.630747709255539 0.711483416040248 SERPINE1 1 GO:0006639 acylglycerol metabolic process 2/313 128/18722 0.633945837717624 0.714667398339056 CAV1/GPX1 2 GO:0035303 regulation of dephosphorylation 2/313 128/18722 0.633945837717624 0.714667398339056 CALM1/PPP1R15A 2 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 1/313 60/18722 0.636940495356542 0.717193867442282 HSPA1A 1 GO:0035825 homologous recombination 1/313 60/18722 0.636940495356542 0.717193867442282 TOP2A 1 GO:0042306 regulation of protein import into nucleus 1/313 60/18722 0.636940495356542 0.717193867442282 FERMT1 1 GO:1903670 regulation of sprouting angiogenesis 1/313 60/18722 0.636940495356542 0.717193867442282 PKM 1 GO:0051321 meiotic cell cycle 4/313 261/18722 0.637856986596252 0.71772182874961 MYH9/PTTG1/CDC20/TOP2A 4 GO:0006022 aminoglycan metabolic process 2/313 129/18722 0.638163485767647 0.71772182874961 ITIH5/B3GNT2 2 GO:0006638 neutral lipid metabolic process 2/313 129/18722 0.638163485767647 0.71772182874961 CAV1/GPX1 2 GO:0007127 meiosis I 2/313 129/18722 0.638163485767647 0.71772182874961 PTTG1/TOP2A 2 GO:0006282 regulation of DNA repair 2/313 130/18722 0.642342985601638 0.721064579979011 FUS/PARP1 2 GO:0007098 centrosome cycle 2/313 130/18722 0.642342985601638 0.721064579979011 SLC16A1/PLK2 2 GO:0015918 sterol transport 2/313 130/18722 0.642342985601638 0.721064579979011 CAV1/CLU 2 GO:0019748 secondary metabolic process 1/313 61/18722 0.643029747577815 0.721064579979011 AKR1B1 1 GO:0043954 cellular component maintenance 1/313 61/18722 0.643029747577815 0.721064579979011 INSR 1 GO:0050994 regulation of lipid catabolic process 1/313 61/18722 0.643029747577815 0.721064579979011 IDH1 1 GO:0060997 dendritic spine morphogenesis 1/313 61/18722 0.643029747577815 0.721064579979011 CFL1 1 GO:0060998 regulation of dendritic spine development 1/313 61/18722 0.643029747577815 0.721064579979011 PLK2 1 GO:1905515 non-motile cilium assembly 1/313 61/18722 0.643029747577815 0.721064579979011 TMEM107 1 GO:2000401 regulation of lymphocyte migration 1/313 61/18722 0.643029747577815 0.721064579979011 RHOA 1 GO:1904950 negative regulation of establishment of protein localization 2/313 131/18722 0.646484429592084 0.72472503635367 ANXA1/FERMT1 2 GO:0002260 lymphocyte homeostasis 1/313 62/18722 0.649017191391552 0.725428199538355 PMAIP1 1 GO:0007062 sister chromatid cohesion 1/313 62/18722 0.649017191391552 0.725428199538355 CDC20 1 GO:0007588 excretion 1/313 62/18722 0.649017191391552 0.725428199538355 CLN3 1 GO:0010573 vascular endothelial growth factor production 1/313 62/18722 0.649017191391552 0.725428199538355 ISL1 1 GO:0019933 cAMP-mediated signaling 1/313 62/18722 0.649017191391552 0.725428199538355 RGS2 1 GO:0031124 mRNA 3'-end processing 1/313 62/18722 0.649017191391552 0.725428199538355 CCNB1 1 GO:0032615 interleukin-12 production 1/313 62/18722 0.649017191391552 0.725428199538355 ISL1 1 GO:0032655 regulation of interleukin-12 production 1/313 62/18722 0.649017191391552 0.725428199538355 ISL1 1 GO:0048002 antigen processing and presentation of peptide antigen 1/313 62/18722 0.649017191391552 0.725428199538355 LGMN 1 GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 1/313 62/18722 0.649017191391552 0.725428199538355 CTNND1 1 GO:0006323 DNA packaging 3/313 199/18722 0.649579713835627 0.725498478943705 TOP2A/CCNB1/BRD2 3 GO:0051607 defense response to virus 4/313 265/18722 0.649651776915968 0.725498478943705 HTRA1/PMAIP1/SERINC5/EXOC1 4 GO:0140546 defense response to symbiont 4/313 265/18722 0.649651776915968 0.725498478943705 HTRA1/PMAIP1/SERINC5/EXOC1 4 GO:0099003 vesicle-mediated transport in synapse 3/313 200/18722 0.652918834835138 0.728933139066678 ACTG1/CALM1/ACTB 3 GO:0009855 determination of bilateral symmetry 2/313 133/18722 0.654653557055644 0.730293357165349 GALNT11/TMEM107 2 GO:0002704 negative regulation of leukocyte mediated immunity 1/313 63/18722 0.654904523604545 0.730293357165349 SERPINB9 1 GO:0045143 homologous chromosome segregation 1/313 63/18722 0.654904523604545 0.730293357165349 PTTG1 1 GO:1904589 regulation of protein import 1/313 63/18722 0.654904523604545 0.730293357165349 FERMT1 1 GO:0006403 RNA localization 3/313 201/18722 0.656235233441824 0.731562967412306 YBX1/SSB/EIF5A 3 GO:0009799 specification of symmetry 2/313 134/18722 0.658681461973412 0.73407503680702 GALNT11/TMEM107 2 GO:0019722 calcium-mediated signaling 3/313 202/18722 0.659528895733168 0.734382429972213 GSTO1/FHL2/CALM1 3 GO:0030858 positive regulation of epithelial cell differentiation 1/313 64/18722 0.660693412832895 0.734382429972213 SERPINE1 1 GO:0030888 regulation of B cell proliferation 1/313 64/18722 0.660693412832895 0.734382429972213 MIF 1 GO:0046530 photoreceptor cell differentiation 1/313 64/18722 0.660693412832895 0.734382429972213 RDH13 1 GO:0046888 negative regulation of hormone secretion 1/313 64/18722 0.660693412832895 0.734382429972213 GJA1 1 GO:0050771 negative regulation of axonogenesis 1/313 64/18722 0.660693412832895 0.734382429972213 SEMA6D 1 GO:0070542 response to fatty acid 1/313 64/18722 0.660693412832895 0.734382429972213 CCNB1 1 GO:1903018 regulation of glycoprotein metabolic process 1/313 64/18722 0.660693412832895 0.734382429972213 ITM2B 1 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process 1/313 64/18722 0.660693412832895 0.734382429972213 RPL23 1 GO:0042157 lipoprotein metabolic process 2/313 135/18722 0.662671753404214 0.736151550980403 DBI/NMT1 2 GO:0061982 meiosis I cell cycle process 2/313 135/18722 0.662671753404214 0.736151550980403 PTTG1/TOP2A 2 GO:0002720 positive regulation of cytokine production involved in immune response 1/313 65/18722 0.666385499968885 0.73817326801463 SLC7A5 1 GO:0035418 protein localization to synapse 1/313 65/18722 0.666385499968885 0.73817326801463 HSPB1 1 GO:0038034 signal transduction in absence of ligand 1/313 65/18722 0.666385499968885 0.73817326801463 HSPA1A 1 GO:0046503 glycerolipid catabolic process 1/313 65/18722 0.666385499968885 0.73817326801463 PRDX6 1 GO:0051310 metaphase plate congression 1/313 65/18722 0.666385499968885 0.73817326801463 CCNB1 1 GO:0060389 pathway-restricted SMAD protein phosphorylation 1/313 65/18722 0.666385499968885 0.73817326801463 TGFBR3 1 GO:0061512 protein localization to cilium 1/313 65/18722 0.666385499968885 0.73817326801463 TMEM107 1 GO:0072577 endothelial cell apoptotic process 1/313 65/18722 0.666385499968885 0.73817326801463 SERPINE1 1 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 1/313 65/18722 0.666385499968885 0.73817326801463 HSPA1A 1 GO:0072073 kidney epithelium development 2/313 136/18722 0.666624558821723 0.73817326801463 MAGED1/HES1 2 GO:0099024 plasma membrane invagination 2/313 136/18722 0.666624558821723 0.73817326801463 MYH9/RHOA 2 GO:0008203 cholesterol metabolic process 2/313 137/18722 0.670540011944414 0.742077274846623 CYP11A1/DHCR24 2 GO:0010977 negative regulation of neuron projection development 2/313 137/18722 0.670540011944414 0.742077274846623 SEMA6D/RHOA 2 GO:0042093 T-helper cell differentiation 1/313 66/18722 0.671982398640147 0.742809811737235 ANXA1 1 GO:0046626 regulation of insulin receptor signaling pathway 1/313 66/18722 0.671982398640147 0.742809811737235 IGF2 1 GO:1902476 chloride transmembrane transport 1/313 66/18722 0.671982398640147 0.742809811737235 SLC26A2 1 GO:2000573 positive regulation of DNA biosynthetic process 1/313 66/18722 0.671982398640147 0.742809811737235 MAP3K4 1 GO:0000724 double-strand break repair via homologous recombination 2/313 138/18722 0.674418252492561 0.744637554303707 FUS/PARP1 2 GO:0007224 smoothened signaling pathway 2/313 138/18722 0.674418252492561 0.744637554303707 FKBP8/HES1 2 GO:0035107 appendage morphogenesis 2/313 138/18722 0.674418252492561 0.744637554303707 SOX4/TMEM107 2 GO:0035108 limb morphogenesis 2/313 138/18722 0.674418252492561 0.744637554303707 SOX4/TMEM107 2 GO:0006513 protein monoubiquitination 1/313 67/18722 0.677485695661247 0.745861203985646 PDCD6 1 GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 1/313 67/18722 0.677485695661247 0.745861203985646 ANXA1 1 GO:0009583 detection of light stimulus 1/313 67/18722 0.677485695661247 0.745861203985646 NMT1 1 GO:0016445 somatic diversification of immunoglobulins 1/313 67/18722 0.677485695661247 0.745861203985646 CTNNBL1 1 GO:0042130 negative regulation of T cell proliferation 1/313 67/18722 0.677485695661247 0.745861203985646 CEBPB 1 GO:0043967 histone H4 acetylation 1/313 67/18722 0.677485695661247 0.745861203985646 MORF4L2 1 GO:0050435 amyloid-beta metabolic process 1/313 67/18722 0.677485695661247 0.745861203985646 CLU 1 GO:0072665 protein localization to vacuole 1/313 67/18722 0.677485695661247 0.745861203985646 CLU 1 GO:1902117 positive regulation of organelle assembly 1/313 67/18722 0.677485695661247 0.745861203985646 RHOA 1 GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 1/313 67/18722 0.677485695661247 0.745861203985646 ANXA1 1 GO:0006836 neurotransmitter transport 3/313 208/18722 0.678813126876446 0.747106555079107 SLC6A8/ITGB1/CALM1 3 GO:0000725 recombinational repair 2/313 140/18722 0.682063683341466 0.749866943835025 FUS/PARP1 2 GO:0015748 organophosphate ester transport 2/313 140/18722 0.682063683341466 0.749866943835025 DBI/GJA1 2 GO:0050768 negative regulation of neurogenesis 2/313 140/18722 0.682063683341466 0.749866943835025 SEMA6D/HES1 2 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 1/313 68/18722 0.682896951477812 0.749866943835025 ANXA1 1 GO:0034394 protein localization to cell surface 1/313 68/18722 0.682896951477812 0.749866943835025 JAM3 1 GO:0061912 selective autophagy 1/313 68/18722 0.682896951477812 0.749866943835025 UBA5 1 GO:1902305 regulation of sodium ion transmembrane transport 1/313 68/18722 0.682896951477812 0.749866943835025 FXYD3 1 GO:1904888 cranial skeletal system development 1/313 68/18722 0.682896951477812 0.749866943835025 TMEM107 1 GO:0050866 negative regulation of cell activation 3/313 210/18722 0.68505931376095 0.752024454292946 ANXA1/CEBPB/ID2 3 GO:1903038 negative regulation of leukocyte cell-cell adhesion 2/313 141/18722 0.685831180992526 0.75245398799451 ANXA1/CEBPB 2 GO:0007281 germ cell development 4/313 278/18722 0.686202447106876 0.75245398799451 DYNLL1/LGR5/JAM3/CCNB1 4 GO:0002287 alpha-beta T cell activation involved in immune response 1/313 69/18722 0.688217700603332 0.75245398799451 ANXA1 1 GO:0002293 alpha-beta T cell differentiation involved in immune response 1/313 69/18722 0.688217700603332 0.75245398799451 ANXA1 1 GO:0003143 embryonic heart tube morphogenesis 1/313 69/18722 0.688217700603332 0.75245398799451 HES1 1 GO:0006368 transcription elongation from RNA polymerase II promoter 1/313 69/18722 0.688217700603332 0.75245398799451 SERTAD1 1 GO:0007004 telomere maintenance via telomerase 1/313 69/18722 0.688217700603332 0.75245398799451 MAP3K4 1 GO:0019226 transmission of nerve impulse 1/313 69/18722 0.688217700603332 0.75245398799451 JAM3 1 GO:0033344 cholesterol efflux 1/313 69/18722 0.688217700603332 0.75245398799451 CAV1 1 GO:0050688 regulation of defense response to virus 1/313 69/18722 0.688217700603332 0.75245398799451 HTRA1 1 GO:0050805 negative regulation of synaptic transmission 1/313 69/18722 0.688217700603332 0.75245398799451 PLK2 1 GO:0050810 regulation of steroid biosynthetic process 1/313 69/18722 0.688217700603332 0.75245398799451 EGR1 1 GO:0051966 regulation of synaptic transmission, glutamatergic 1/313 69/18722 0.688217700603332 0.75245398799451 CLN3 1 GO:1901224 positive regulation of NIK/NF-kappaB signaling 1/313 69/18722 0.688217700603332 0.75245398799451 RHOA 1 GO:0031023 microtubule organizing center organization 2/313 143/18722 0.693256547644919 0.757745528821191 SLC16A1/PLK2 2 GO:0001505 regulation of neurotransmitter levels 3/313 213/18722 0.694258489528242 0.758622867288754 ITGB1/CALM1/CLN3 3 GO:0010324 membrane invagination 2/313 144/18722 0.696914753919986 0.761088487714684 MYH9/RHOA 2 GO:0033135 regulation of peptidyl-serine phosphorylation 2/313 144/18722 0.696914753919986 0.761088487714684 CAV1/MIF 2 GO:0032722 positive regulation of chemokine production 1/313 71/18722 0.698593689744896 0.761829325940653 EGR1 1 GO:0033555 multicellular organismal response to stress 1/313 71/18722 0.698593689744896 0.761829325940653 GJA1 1 GO:0043550 regulation of lipid kinase activity 1/313 71/18722 0.698593689744896 0.761829325940653 FLT1 1 GO:0045824 negative regulation of innate immune response 1/313 71/18722 0.698593689744896 0.761829325940653 SERPINB9 1 GO:0061515 myeloid cell development 1/313 71/18722 0.698593689744896 0.761829325940653 FBN1 1 GO:0051961 negative regulation of nervous system development 2/313 145/18722 0.70053687459503 0.763729633901283 SEMA6D/HES1 2 GO:0001736 establishment of planar polarity 1/313 72/18722 0.70365187295812 0.765590934653205 RHOA 1 GO:0007164 establishment of tissue polarity 1/313 72/18722 0.70365187295812 0.765590934653205 RHOA 1 GO:0030032 lamellipodium assembly 1/313 72/18722 0.70365187295812 0.765590934653205 ITGB1 1 GO:0035567 non-canonical Wnt signaling pathway 1/313 72/18722 0.70365187295812 0.765590934653205 RHOA 1 GO:0042273 ribosomal large subunit biogenesis 1/313 72/18722 0.70365187295812 0.765590934653205 RPL38 1 GO:0050709 negative regulation of protein secretion 1/313 72/18722 0.70365187295812 0.765590934653205 ANXA1 1 GO:1901880 negative regulation of protein depolymerization 1/313 72/18722 0.70365187295812 0.765590934653205 SCIN 1 GO:0006887 exocytosis 5/313 352/18722 0.703921831531855 0.765665832183363 ANXA1/MYH9/SCIN/CALM1/EXOC1 5 GO:0048813 dendrite morphogenesis 2/313 146/18722 0.704123089387329 0.765665981518869 CFL1/ITGB1 2 GO:0002637 regulation of immunoglobulin production 1/313 73/18722 0.708625436698823 0.768805083360621 TMBIM6 1 GO:0009166 nucleotide catabolic process 1/313 73/18722 0.708625436698823 0.768805083360621 PDE4B 1 GO:0032456 endocytic recycling 1/313 73/18722 0.708625436698823 0.768805083360621 RAB17 1 GO:0042058 regulation of epidermal growth factor receptor signaling pathway 1/313 73/18722 0.708625436698823 0.768805083360621 ERRFI1 1 GO:0051145 smooth muscle cell differentiation 1/313 73/18722 0.708625436698823 0.768805083360621 HES1 1 GO:0051298 centrosome duplication 1/313 73/18722 0.708625436698823 0.768805083360621 PLK2 1 GO:0061035 regulation of cartilage development 1/313 73/18722 0.708625436698823 0.768805083360621 SCIN 1 GO:0099518 vesicle cytoskeletal trafficking 1/313 73/18722 0.708625436698823 0.768805083360621 CLN3 1 GO:0071805 potassium ion transmembrane transport 3/313 219/18722 0.71204735354308 0.772297514227494 CAV1/CD63/ITGB1 3 GO:0007040 lysosome organization 1/313 74/18722 0.713515792123418 0.773009283043213 CLN3 1 GO:0046470 phosphatidylcholine metabolic process 1/313 74/18722 0.713515792123418 0.773009283043213 DBI 1 GO:0080171 lytic vacuole organization 1/313 74/18722 0.713515792123418 0.773009283043213 CLN3 1 GO:1901568 fatty acid derivative metabolic process 1/313 74/18722 0.713515792123418 0.773009283043213 TECR 1 GO:0045834 positive regulation of lipid metabolic process 2/313 149/18722 0.714668155779944 0.774037459190397 ANXA1/FLT1 2 GO:0031503 protein-containing complex localization 3/313 220/18722 0.714933602892468 0.774104728729131 EZR/BIRC5/SSB 3 GO:0001959 regulation of cytokine-mediated signaling pathway 2/313 150/18722 0.718112623123088 0.776451082515878 CAV1/HSPA1A 2 GO:0002292 T cell differentiation involved in immune response 1/313 75/18722 0.718324326929583 0.776451082515878 ANXA1 1 GO:0006024 glycosaminoglycan biosynthetic process 1/313 75/18722 0.718324326929583 0.776451082515878 B3GNT2 1 GO:0006278 RNA-dependent DNA biosynthetic process 1/313 75/18722 0.718324326929583 0.776451082515878 MAP3K4 1 GO:0034121 regulation of toll-like receptor signaling pathway 1/313 75/18722 0.718324326929583 0.776451082515878 CAV1 1 GO:1903363 negative regulation of cellular protein catabolic process 1/313 75/18722 0.718324326929583 0.776451082515878 RPL23 1 GO:0048754 branching morphogenesis of an epithelial tube 2/313 151/18722 0.721522140778653 0.779465036874101 CLIC4/MAGED1 2 GO:0055067 monovalent inorganic cation homeostasis 2/313 151/18722 0.721522140778653 0.779465036874101 CLIC4/CLN3 2 GO:0032720 negative regulation of tumor necrosis factor production 1/313 76/18722 0.723052405744998 0.780675130082589 ERRFI1 1 GO:0071426 ribonucleoprotein complex export from nucleus 1/313 76/18722 0.723052405744998 0.780675130082589 SSB 1 GO:0002200 somatic diversification of immune receptors 1/313 77/18722 0.727701370509656 0.784582021390615 CTNNBL1 1 GO:0007492 endoderm development 1/313 77/18722 0.727701370509656 0.784582021390615 FN1 1 GO:0010827 regulation of glucose transmembrane transport 1/313 77/18722 0.727701370509656 0.784582021390615 INSR 1 GO:0032418 lysosome localization 1/313 77/18722 0.727701370509656 0.784582021390615 MYH9 1 GO:0071166 ribonucleoprotein complex localization 1/313 77/18722 0.727701370509656 0.784582021390615 SSB 1 GO:0050769 positive regulation of neurogenesis 3/313 225/18722 0.729031079888771 0.785793126029601 FN1/ID2/HES1 3 GO:0050767 regulation of neurogenesis 5/313 364/18722 0.731159916602013 0.786614436518919 FN1/SEMA6D/BHLHE41/ID2/HES1 5 GO:0050770 regulation of axonogenesis 2/313 154/18722 0.731543025968893 0.786614436518919 FN1/SEMA6D 2 GO:0048193 Golgi vesicle transport 4/313 296/18722 0.732255355469125 0.786614436518919 KRT18/PDCD6/CLN3/EXOC1 4 GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 1/313 78/18722 0.732272540851865 0.786614436518919 RGS2 1 GO:0009064 glutamine family amino acid metabolic process 1/313 78/18722 0.732272540851865 0.786614436518919 CLN3 1 GO:0030500 regulation of bone mineralization 1/313 78/18722 0.732272540851865 0.786614436518919 ATP2B1 1 GO:0032371 regulation of sterol transport 1/313 78/18722 0.732272540851865 0.786614436518919 CAV1 1 GO:0032374 regulation of cholesterol transport 1/313 78/18722 0.732272540851865 0.786614436518919 CAV1 1 GO:0035050 embryonic heart tube development 1/313 78/18722 0.732272540851865 0.786614436518919 HES1 1 GO:0043537 negative regulation of blood vessel endothelial cell migration 1/313 78/18722 0.732272540851865 0.786614436518919 RHOA 1 GO:1901616 organic hydroxy compound catabolic process 1/313 78/18722 0.732272540851865 0.786614436518919 TPI1 1 GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 1/313 78/18722 0.732272540851865 0.786614436518919 ERRFI1 1 GO:0000245 spliceosomal complex assembly 1/313 79/18722 0.736767214458031 0.790105009983585 SCAF11 1 GO:0006023 aminoglycan biosynthetic process 1/313 79/18722 0.736767214458031 0.790105009983585 B3GNT2 1 GO:0006029 proteoglycan metabolic process 1/313 79/18722 0.736767214458031 0.790105009983585 EXTL2 1 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 1/313 79/18722 0.736767214458031 0.790105009983585 S100A10 1 GO:0050772 positive regulation of axonogenesis 1/313 79/18722 0.736767214458031 0.790105009983585 FN1 1 GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 1/313 79/18722 0.736767214458031 0.790105009983585 GAPDH 1 GO:0010720 positive regulation of cell development 4/313 298/18722 0.737046282821491 0.790181694931404 FN1/S100A10/ID2/HES1 4 GO:0046631 alpha-beta T cell activation 2/313 156/18722 0.738052640478887 0.791037838486239 ANXA1/RHOA 2 GO:0007422 peripheral nervous system development 1/313 80/18722 0.741186667436341 0.793578349739693 ISL1 1 GO:0021766 hippocampus development 1/313 80/18722 0.741186667436341 0.793578349739693 BTG2 1 GO:0051303 establishment of chromosome localization 1/313 80/18722 0.741186667436341 0.793578349739693 CCNB1 1 GO:1902600 proton transmembrane transport 2/313 157/18722 0.741256793190005 0.793578349739693 COX4I1/TMSB4X 2 GO:0045055 regulated exocytosis 3/313 230/18722 0.742577716428172 0.794769009401758 MYH9/SCIN/CALM1 3 GO:0001960 negative regulation of cytokine-mediated signaling pathway 1/313 81/18722 0.745532154674429 0.797034797204591 CAV1 1 GO:0051149 positive regulation of muscle cell differentiation 1/313 81/18722 0.745532154674429 0.797034797204591 MORF4L2 1 GO:1903533 regulation of protein targeting 1/313 81/18722 0.745532154674429 0.797034797204591 TCAF1 1 GO:2000106 regulation of leukocyte apoptotic process 1/313 81/18722 0.745532154674429 0.797034797204591 ANXA1 1 GO:0001910 regulation of leukocyte mediated cytotoxicity 1/313 82/18722 0.749804910191134 0.800254357470605 SERPINB9 1 GO:0016575 histone deacetylation 1/313 82/18722 0.749804910191134 0.800254357470605 MORF4L2 1 GO:0043242 negative regulation of protein-containing complex disassembly 1/313 82/18722 0.749804910191134 0.800254357470605 SCIN 1 GO:0046889 positive regulation of lipid biosynthetic process 1/313 82/18722 0.749804910191134 0.800254357470605 ANXA1 1 GO:0050000 chromosome localization 1/313 82/18722 0.749804910191134 0.800254357470605 CCNB1 1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic 1/313 82/18722 0.749804910191134 0.800254357470605 RPS21 1 GO:0006310 DNA recombination 4/313 305/18722 0.753306745989145 0.803611815079982 HMGB3/FUS/PARP1/TOP2A 4 GO:0051960 regulation of nervous system development 6/313 443/18722 0.753672059050908 0.803611815079982 FN1/SEMA6D/CTSC/BHLHE41/ID2/HES1 6 GO:0043367 CD4-positive, alpha-beta T cell differentiation 1/313 83/18722 0.754006147482452 0.803611815079982 ANXA1 1 GO:0050672 negative regulation of lymphocyte proliferation 1/313 83/18722 0.754006147482452 0.803611815079982 CEBPB 1 GO:1901292 nucleoside phosphate catabolic process 1/313 83/18722 0.754006147482452 0.803611815079982 PDE4B 1 GO:0044282 small molecule catabolic process 5/313 376/18722 0.756546671449317 0.805758734476197 CROT/TPI1/ENO1/SLC27A2/NPL 5 GO:0060759 regulation of response to cytokine stimulus 2/313 162/18722 0.756779773115351 0.805758734476197 CAV1/HSPA1A 2 GO:0046395 carboxylic acid catabolic process 3/313 236/18722 0.7581186807896 0.805758734476197 CROT/SLC27A2/NPL 3 GO:0006405 RNA export from nucleus 1/313 84/18722 0.758137059861764 0.805758734476197 SSB 1 GO:0009953 dorsal/ventral pattern formation 1/313 84/18722 0.758137059861764 0.805758734476197 FKBP8 1 GO:0010660 regulation of muscle cell apoptotic process 1/313 84/18722 0.758137059861764 0.805758734476197 PPP1R10 1 GO:0032945 negative regulation of mononuclear cell proliferation 1/313 84/18722 0.758137059861764 0.805758734476197 CEBPB 1 GO:0042440 pigment metabolic process 1/313 84/18722 0.758137059861764 0.805758734476197 BLVRA 1 GO:0061157 mRNA destabilization 1/313 84/18722 0.758137059861764 0.805758734476197 BTG2 1 GO:0098586 cellular response to virus 1/313 84/18722 0.758137059861764 0.805758734476197 EIF5A 1 GO:0006909 phagocytosis 4/313 308/18722 0.760035624847808 0.807551109069384 ANXA1/MYH9/ITGB1/CLN3 4 GO:0002700 regulation of production of molecular mediator of immune response 2/313 164/18722 0.762760846183632 0.809994572223455 SLC7A5/TMBIM6 2 GO:0050806 positive regulation of synaptic transmission 2/313 164/18722 0.762760846183632 0.809994572223455 PLK2/LGMN 2 GO:0007286 spermatid development 2/313 165/18722 0.765703410977867 0.811827210729735 DYNLL1/JAM3 2 GO:0032635 interleukin-6 production 2/313 165/18722 0.765703410977867 0.811827210729735 ISL1/CEBPB 2 GO:0032675 regulation of interleukin-6 production 2/313 165/18722 0.765703410977867 0.811827210729735 ISL1/CEBPB 2 GO:0046661 male sex differentiation 2/313 165/18722 0.765703410977867 0.811827210729735 YBX3/DHCR24 2 GO:0009798 axis specification 1/313 86/18722 0.766192584226934 0.811827210729735 WLS 1 GO:0034103 regulation of tissue remodeling 1/313 86/18722 0.766192584226934 0.811827210729735 TMBIM1 1 GO:0046928 regulation of neurotransmitter secretion 1/313 86/18722 0.766192584226934 0.811827210729735 CALM1 1 GO:0060761 negative regulation of response to cytokine stimulus 1/313 86/18722 0.766192584226934 0.811827210729735 CAV1 1 GO:0016054 organic acid catabolic process 3/313 240/18722 0.768053856117012 0.813346600900546 CROT/SLC27A2/NPL 3 GO:0050851 antigen receptor-mediated signaling pathway 3/313 240/18722 0.768053856117012 0.813346600900546 PHPT1/EZR/PDE4B 3 GO:0030307 positive regulation of cell growth 2/313 166/18722 0.768614302582731 0.813669245866694 FN1/RHOA 2 GO:0019932 second-messenger-mediated signaling 4/313 312/18722 0.768785993533621 0.813669245866694 GSTO1/FHL2/CALM1/RGS2 4 GO:0007029 endoplasmic reticulum organization 1/313 87/18722 0.770119484910395 0.813949161314234 CAV2 1 GO:0051262 protein tetramerization 1/313 87/18722 0.770119484910395 0.813949161314234 ALDOA 1 GO:0061014 positive regulation of mRNA catabolic process 1/313 87/18722 0.770119484910395 0.813949161314234 BTG2 1 GO:1900182 positive regulation of protein localization to nucleus 1/313 87/18722 0.770119484910395 0.813949161314234 PARP1 1 GO:1901879 regulation of protein depolymerization 1/313 87/18722 0.770119484910395 0.813949161314234 SCIN 1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 2/313 167/18722 0.771493753508316 0.814949145284728 BSG/ITGB1 2 GO:0007254 JNK cascade 2/313 167/18722 0.771493753508316 0.814949145284728 GADD45B/HACD3 2 GO:0030101 natural killer cell activation 1/313 88/18722 0.773980638718983 0.816669703881144 PRDX1 1 GO:0050779 RNA destabilization 1/313 88/18722 0.773980638718983 0.816669703881144 BTG2 1 GO:0050829 defense response to Gram-negative bacterium 1/313 88/18722 0.773980638718983 0.816669703881144 SERPINE1 1 GO:1901657 glycosyl compound metabolic process 1/313 88/18722 0.773980638718983 0.816669703881144 AKR1B1 1 GO:0016482 cytosolic transport 2/313 168/18722 0.77434199736446 0.816824600711138 EZR/CLN3 2 GO:0031214 biomineral tissue development 2/313 169/18722 0.777159268759418 0.819569345198644 ATP2B1/CEBPB 2 GO:0010657 muscle cell apoptotic process 1/313 89/18722 0.77777714296289 0.819766772774009 PPP1R10 1 GO:0046330 positive regulation of JNK cascade 1/313 89/18722 0.77777714296289 0.819766772774009 GADD45B 1 GO:0009100 glycoprotein metabolic process 5/313 387/18722 0.778210089774728 0.819996073006474 GALNT11/ITM2B/VEGFB/EXTL2/B3GNT2 5 GO:0006400 tRNA modification 1/313 90/18722 0.781510076696192 0.822335229956441 SSB 1 GO:0034644 cellular response to UV 1/313 90/18722 0.781510076696192 0.822335229956441 PARP1 1 GO:0046849 bone remodeling 1/313 90/18722 0.781510076696192 0.822335229956441 GJA1 1 GO:0070664 negative regulation of leukocyte proliferation 1/313 90/18722 0.781510076696192 0.822335229956441 CEBPB 1 GO:0097581 lamellipodium organization 1/313 90/18722 0.781510076696192 0.822335229956441 ITGB1 1 GO:0110148 biomineralization 2/313 171/18722 0.78270183700429 0.823361672692825 ATP2B1/CEBPB 2 GO:0006354 DNA-templated transcription, elongation 1/313 91/18722 0.785180501019619 0.824295159376685 SERTAD1 1 GO:0019935 cyclic-nucleotide-mediated signaling 1/313 91/18722 0.785180501019619 0.824295159376685 RGS2 1 GO:0002221 pattern recognition receptor signaling pathway 2/313 172/18722 0.785427607193291 0.824295159376685 CAV1/HSPA1A 2 GO:0048515 spermatid differentiation 2/313 172/18722 0.785427607193291 0.824295159376685 DYNLL1/JAM3 2 GO:0048736 appendage development 2/313 172/18722 0.785427607193291 0.824295159376685 SOX4/TMEM107 2 GO:0060173 limb development 2/313 172/18722 0.785427607193291 0.824295159376685 SOX4/TMEM107 2 GO:1901136 carbohydrate derivative catabolic process 2/313 172/18722 0.785427607193291 0.824295159376685 PDE4B/NPL 2 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 4/313 320/18722 0.785537913900345 0.824295159376685 DDX5/PRDX6/TRA2B/SCAF11 4 GO:0000398 mRNA splicing, via spliceosome 4/313 320/18722 0.785537913900345 0.824295159376685 DDX5/PRDX6/TRA2B/SCAF11 4 GO:0035249 synaptic transmission, glutamatergic 1/313 92/18722 0.788789459378315 0.827023264074151 CLN3 1 GO:0048525 negative regulation of viral process 1/313 92/18722 0.788789459378315 0.827023264074151 LY6E 1 GO:1903351 cellular response to dopamine 1/313 92/18722 0.788789459378315 0.827023264074151 CAV2 1 GO:0016570 histone modification 6/313 463/18722 0.789591223374503 0.827635954676964 IGF2/MBD3/ISL1/PRMT1/MORF4L2/CCNB1 6 GO:0007589 body fluid secretion 1/313 93/18722 0.792337977854675 0.829373297138506 CAV1 1 GO:0032755 positive regulation of interleukin-6 production 1/313 93/18722 0.792337977854675 0.829373297138506 ISL1 1 GO:0033108 mitochondrial respiratory chain complex assembly 1/313 93/18722 0.792337977854675 0.829373297138506 NDUFB1 1 GO:0060349 bone morphogenesis 1/313 93/18722 0.792337977854675 0.829373297138506 TMEM107 1 GO:1903350 response to dopamine 1/313 93/18722 0.792337977854675 0.829373297138506 CAV2 1 GO:0034470 ncRNA processing 5/313 395/18722 0.793017391135725 0.829856296881172 RPS27/RPS17/RPS21/RPS28/SSB 5 GO:0000375 RNA splicing, via transesterification reactions 4/313 324/18722 0.793545717965245 0.83018096957782 DDX5/PRDX6/TRA2B/SCAF11 4 GO:0010389 regulation of G2/M transition of mitotic cell cycle 1/313 94/18722 0.795827065456343 0.832338911591291 CCNB1 1 GO:0030324 lung development 2/313 177/18722 0.798610838663382 0.835009362985373 ERRFI1/HES1 2 GO:0002532 production of molecular mediator involved in inflammatory response 1/313 95/18722 0.799257714399449 0.835009362985373 SERPINE1 1 GO:0032479 regulation of type I interferon production 1/313 95/18722 0.799257714399449 0.835009362985373 GAPDH 1 GO:0032606 type I interferon production 1/313 95/18722 0.799257714399449 0.835009362985373 GAPDH 1 GO:0035725 sodium ion transmembrane transport 2/313 178/18722 0.801160033677681 0.83669656017905 SLC6A8/FXYD3 2 GO:0043547 positive regulation of GTPase activity 3/313 255/18722 0.802386866962812 0.83669656017905 CAV2/ITGB1/S100A10 3 GO:0002718 regulation of cytokine production involved in immune response 1/313 96/18722 0.802630900387153 0.83669656017905 SLC7A5 1 GO:0015914 phospholipid transport 1/313 96/18722 0.802630900387153 0.83669656017905 DBI 1 GO:0035282 segmentation 1/313 96/18722 0.802630900387153 0.83669656017905 NRP2 1 GO:0042632 cholesterol homeostasis 1/313 96/18722 0.802630900387153 0.83669656017905 CAV1 1 GO:0043648 dicarboxylic acid metabolic process 1/313 96/18722 0.802630900387153 0.83669656017905 IDH1 1 GO:1904035 regulation of epithelial cell apoptotic process 1/313 96/18722 0.802630900387153 0.83669656017905 SERPINE1 1 GO:0010596 negative regulation of endothelial cell migration 1/313 97/18722 0.8059475828836 0.839234805261998 RHOA 1 GO:0055092 sterol homeostasis 1/313 97/18722 0.8059475828836 0.839234805261998 CAV1 1 GO:1990868 response to chemokine 1/313 97/18722 0.8059475828836 0.839234805261998 RHOA 1 GO:1990869 cellular response to chemokine 1/313 97/18722 0.8059475828836 0.839234805261998 RHOA 1 GO:0071897 DNA biosynthetic process 2/313 180/18722 0.806172888451903 0.839239865008585 GJA1/MAP3K4 2 GO:0006479 protein methylation 2/313 181/18722 0.808637027669384 0.841115072223319 PRMT1/BTG2 2 GO:0008213 protein alkylation 2/313 181/18722 0.808637027669384 0.841115072223319 PRMT1/BTG2 2 GO:0030323 respiratory tube development 2/313 181/18722 0.808637027669384 0.841115072223319 ERRFI1/HES1 2 GO:0002367 cytokine production involved in immune response 1/313 98/18722 0.809208705383328 0.841250011303749 SLC7A5 1 GO:0032642 regulation of chemokine production 1/313 98/18722 0.809208705383328 0.841250011303749 EGR1 1 GO:0061138 morphogenesis of a branching epithelium 2/313 182/18722 0.811073294347491 0.84285070920476 CLIC4/MAGED1 2 GO:0002444 myeloid leukocyte mediated immunity 1/313 99/18722 0.812415195676231 0.84285070920476 SERPINB9 1 GO:0007631 feeding behavior 1/313 99/18722 0.812415195676231 0.84285070920476 FOS 1 GO:0010717 regulation of epithelial to mesenchymal transition 1/313 99/18722 0.812415195676231 0.84285070920476 ISL1 1 GO:0031341 regulation of cell killing 1/313 99/18722 0.812415195676231 0.84285070920476 SERPINB9 1 GO:0032602 chemokine production 1/313 99/18722 0.812415195676231 0.84285070920476 EGR1 1 GO:0042100 B cell proliferation 1/313 99/18722 0.812415195676231 0.84285070920476 MIF 1 GO:0042113 B cell activation 4/313 334/18722 0.812519596212627 0.84285070920476 MIF/TPD52/ITGB1/ID2 4 GO:0051091 positive regulation of DNA-binding transcription factor activity 3/313 260/18722 0.812845253114057 0.842958833725202 CAV1/HSPA1A/CLU 3 GO:0006664 glycolipid metabolic process 1/313 100/18722 0.815567966108134 0.845321875026863 ITGB8 1 GO:0019218 regulation of steroid metabolic process 1/313 100/18722 0.815567966108134 0.845321875026863 EGR1 1 GO:0060271 cilium assembly 4/313 337/18722 0.817927083113754 0.847536310673397 DYNLL1/GALNT11/RAB17/TMEM107 4 GO:0006476 protein deacetylation 1/313 101/18722 0.818667913837065 0.847611843344495 MORF4L2 1 GO:0051963 regulation of synapse assembly 1/313 101/18722 0.818667913837065 0.847611843344495 RAB17 1 GO:1903509 liposaccharide metabolic process 1/313 101/18722 0.818667913837065 0.847611843344495 ITGB8 1 GO:0031345 negative regulation of cell projection organization 2/313 186/18722 0.820544423092054 0.849323713624647 SEMA6D/RHOA 2 GO:0002697 regulation of immune effector process 4/313 339/18722 0.821460655034735 0.849381621387907 SERPINB9/ANXA1/SLC7A5/TMBIM6 4 GO:0035710 CD4-positive, alpha-beta T cell activation 1/313 102/18722 0.82171592108528 0.849381621387907 ANXA1 1 GO:0045833 negative regulation of lipid metabolic process 1/313 102/18722 0.82171592108528 0.849381621387907 ORMDL1 1 GO:1902749 regulation of cell cycle G2/M phase transition 1/313 102/18722 0.82171592108528 0.849381621387907 CCNB1 1 GO:1990542 mitochondrial transmembrane transport 1/313 102/18722 0.82171592108528 0.849381621387907 MPC2 1 GO:0034660 ncRNA metabolic process 6/313 485/18722 0.824352004637457 0.851875157886753 RPS27/RPS17/RPS21/RPS28/SSB/KCNQ1OT1 6 GO:1905037 autophagosome organization 1/313 103/18722 0.824712855387122 0.852016781671309 CLN3 1 GO:0022600 digestive system process 1/313 104/18722 0.827659569832787 0.854597228737027 EZR 1 GO:0032006 regulation of TOR signaling 1/313 104/18722 0.827659569832787 0.854597228737027 PDCD6 1 GO:0051216 cartilage development 2/313 190/18722 0.829588705177369 0.856312672124855 SCIN/ITGB8 2 GO:0016311 dephosphorylation 5/313 417/18722 0.829770803117571 0.856312672124855 PHPT1/PTPRA/CALM1/PPP1R15A/PGP 5 GO:0016079 synaptic vesicle exocytosis 1/313 105/18722 0.830556903308044 0.856891634388543 CALM1 1 GO:0001824 blastocyst development 1/313 106/18722 0.833405680730001 0.858667233163495 STMN3 1 GO:0002062 chondrocyte differentiation 1/313 106/18722 0.833405680730001 0.858667233163495 SCIN 1 GO:0019882 antigen processing and presentation 1/313 106/18722 0.833405680730001 0.858667233163495 LGMN 1 GO:0046822 regulation of nucleocytoplasmic transport 1/313 106/18722 0.833405680730001 0.858667233163495 FERMT1 1 GO:0071887 leukocyte apoptotic process 1/313 106/18722 0.833405680730001 0.858667233163495 ANXA1 1 GO:0051962 positive regulation of nervous system development 3/313 272/18722 0.836051518528745 0.860854234032726 FN1/ID2/HES1 3 GO:0006275 regulation of DNA replication 1/313 107/18722 0.836206713278965 0.860854234032726 JUN 1 GO:0032526 response to retinoic acid 1/313 107/18722 0.836206713278965 0.860854234032726 GJA1 1 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 3/313 273/18722 0.837869096479829 0.862332427763912 BSG/ITGB1/CLDN7 3 GO:0006958 complement activation, classical pathway 1/313 108/18722 0.838960798626464 0.862989397560375 CLU 1 GO:0007173 epidermal growth factor receptor signaling pathway 1/313 108/18722 0.838960798626464 0.862989397560375 ERRFI1 1 GO:0002449 lymphocyte mediated immunity 4/313 350/18722 0.839899395022771 0.863488251917821 SERPINB9/PRDX1/CTSC/CLU 4 GO:0042742 defense response to bacterium 4/313 350/18722 0.839899395022771 0.863488251917821 PLAC8/TNFRSF1A/SERPINE1/CEBPB 4 GO:1901605 alpha-amino acid metabolic process 2/313 195/18722 0.840316913798968 0.863684257784199 SERINC5/CLN3 2 GO:0002456 T cell mediated immunity 1/313 109/18722 0.841668721159499 0.86484016773393 CTSC 1 GO:0001763 morphogenesis of a branching structure 2/313 196/18722 0.84238795189743 0.865112202016056 CLIC4/MAGED1 2 GO:0022408 negative regulation of cell-cell adhesion 2/313 196/18722 0.84238795189743 0.865112202016056 ANXA1/CEBPB 2 GO:0031346 positive regulation of cell projection organization 4/313 353/18722 0.844643333719762 0.867194490688008 EPS8L1/FN1/PFN1/RGS2 4 GO:0050864 regulation of B cell activation 2/313 198/18722 0.846457285616866 0.868822563047562 MIF/ID2 2 GO:0010633 negative regulation of epithelial cell migration 1/313 112/18722 0.849523161079811 0.871499508011544 RHOA 1 GO:0035601 protein deacylation 1/313 112/18722 0.849523161079811 0.871499508011544 MORF4L2 1 GO:0001578 microtubule bundle formation 1/313 113/18722 0.852054018177179 0.873860357543244 CAPN6 1 GO:0017157 regulation of exocytosis 2/313 202/18722 0.854311423799488 0.87570473201444 ANXA1/CALM1 2 GO:0002286 T cell activation involved in immune response 1/313 114/18722 0.854542442719634 0.87570473201444 ANXA1 1 GO:1903008 organelle disassembly 1/313 114/18722 0.854542442719634 0.87570473201444 UBA5 1 GO:0060541 respiratory system development 2/313 203/18722 0.856217011978227 0.877184651399653 ERRFI1/HES1 2 GO:0030278 regulation of ossification 1/313 115/18722 0.856989143892718 0.877503407961156 ATP2B1 1 GO:0042471 ear morphogenesis 1/313 115/18722 0.856989143892718 0.877503407961156 RPL38 1 GO:0018107 peptidyl-threonine phosphorylation 1/313 116/18722 0.859394819066662 0.879020976944327 CALM1 1 GO:0030326 embryonic limb morphogenesis 1/313 116/18722 0.859394819066662 0.879020976944327 TMEM107 1 GO:0035113 embryonic appendage morphogenesis 1/313 116/18722 0.859394819066662 0.879020976944327 TMEM107 1 GO:0098732 macromolecule deacylation 1/313 116/18722 0.859394819066662 0.879020976944327 MORF4L2 1 GO:0002702 positive regulation of production of molecular mediator of immune response 1/313 117/18722 0.861760153992608 0.881203574066575 SLC7A5 1 GO:0030282 bone mineralization 1/313 119/18722 0.866372489164275 0.885682080088183 ATP2B1 1 GO:0044782 cilium organization 4/313 368/18722 0.866625155582718 0.885702541557962 DYNLL1/GALNT11/RAB17/TMEM107 4 GO:0002429 immune response-activating cell surface receptor signaling pathway 3/313 291/18722 0.86773109105152 0.886356926115679 PHPT1/EZR/PDE4B 3 GO:0002757 immune response-activating signal transduction 3/313 291/18722 0.86773109105152 0.886356926115679 PHPT1/EZR/PDE4B 3 GO:0071774 response to fibroblast growth factor 1/313 120/18722 0.868620804537687 0.887027736822686 IER2 1 GO:0046474 glycerophospholipid biosynthetic process 2/313 211/18722 0.870662252998124 0.888570136416229 ABHD8/CLN3 2 GO:0002224 toll-like receptor signaling pathway 1/313 121/18722 0.870831410288665 0.888570136416229 CAV1 1 GO:0002455 humoral immune response mediated by circulating immunoglobulin 1/313 121/18722 0.870831410288665 0.888570136416229 CLU 1 GO:0030258 lipid modification 2/313 212/18722 0.872371276868223 0.889902853975703 CROT/SLC27A2 2 GO:0019730 antimicrobial humoral response 1/313 122/18722 0.87300493690442 0.890310687060039 GAPDH 1 GO:0002253 activation of immune response 4/313 375/18722 0.875939131694668 0.893063812094698 PHPT1/EZR/PDE4B/CLU 4 GO:0010508 positive regulation of autophagy 1/313 124/18722 0.877243222313071 0.894153935032359 PLK2 1 GO:0002377 immunoglobulin production 2/313 216/18722 0.879001988876577 0.895706791127711 TMBIM6/CTNNBL1 2 GO:0060294 cilium movement involved in cell motility 1/313 125/18722 0.879309190235214 0.895780060804244 CCSAP 1 GO:0031929 TOR signaling 1/313 126/18722 0.881340497621157 0.897609222697631 PDCD6 1 GO:0006911 phagocytosis, engulfment 1/313 127/18722 0.883337724134632 0.899162223470733 MYH9 1 GO:0008033 tRNA processing 1/313 127/18722 0.883337724134632 0.899162223470733 SSB 1 GO:0048705 skeletal system morphogenesis 2/313 220/18722 0.885314183382925 0.900933198647098 TMEM107/ANKRD11 2 GO:0006334 nucleosome assembly 1/313 129/18722 0.887232205041398 0.90264377461053 BRD2 1 GO:0006352 DNA-templated transcription, initiation 1/313 130/18722 0.889130571083567 0.903609205583326 JUN 1 GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 1/313 130/18722 0.889130571083567 0.903609205583326 PDCD6 1 GO:0006956 complement activation 1/313 130/18722 0.889130571083567 0.903609205583326 CLU 1 GO:0051028 mRNA transport 1/313 130/18722 0.889130571083567 0.903609205583326 EIF5A 1 GO:0006612 protein targeting to membrane 1/313 131/18722 0.890997079864271 0.905264447035836 TCAF1 1 GO:0002440 production of molecular mediator of immune response 3/313 308/18722 0.89138326883808 0.905415182621817 SLC7A5/TMBIM6/CTNNBL1 3 GO:0006997 nucleus organization 1/313 133/18722 0.894636648454345 0.908189548565857 NEK6 1 GO:0046328 regulation of JNK cascade 1/313 133/18722 0.894636648454345 0.908189548565857 GADD45B 1 GO:0002764 immune response-regulating signaling pathway 5/313 468/18722 0.89483031170752 0.908189548565857 CAV1/PHPT1/EZR/PDE4B/HSPA1A 5 GO:0032147 activation of protein kinase activity 1/313 134/18722 0.896410747600818 0.909551097045926 INSR 1 GO:0009581 detection of external stimulus 1/313 135/18722 0.898155068453032 0.911078162963147 NMT1 1 GO:0006605 protein targeting 3/313 314/18722 0.898783641930836 0.911472915511639 TCAF1/HERPUD1/CLU 3 GO:1903305 regulation of regulated secretory pathway 1/313 136/18722 0.899870109265116 0.912192167000823 CALM1 1 GO:0002768 immune response-regulating cell surface receptor signaling pathway 3/313 315/18722 0.899972098569764 0.912192167000823 PHPT1/EZR/PDE4B 3 GO:0007586 digestion 1/313 137/18722 0.901556359980709 0.913554714518647 EZR 1 GO:0001539 cilium or flagellum-dependent cell motility 1/313 138/18722 0.903214302371133 0.914504481150772 CCSAP 1 GO:0009582 detection of abiotic stimulus 1/313 138/18722 0.903214302371133 0.914504481150772 NMT1 1 GO:0060285 cilium-dependent cell motility 1/313 138/18722 0.903214302371133 0.914504481150772 CCSAP 1 GO:0002699 positive regulation of immune effector process 2/313 235/18722 0.90636884744262 0.917454454191453 ANXA1/SLC7A5 2 GO:0008584 male gonad development 1/313 141/18722 0.90802297755765 0.918640307085297 YBX3 1 GO:0016571 histone methylation 1/313 141/18722 0.90802297755765 0.918640307085297 PRMT1 1 GO:0046546 development of primary male sexual characteristics 1/313 142/18722 0.909572345623118 0.919963315565146 YBX3 1 GO:0031644 regulation of nervous system process 1/313 144/18722 0.912593465141029 0.922773790648578 CTSC 1 GO:0071824 protein-DNA complex subunit organization 2/313 241/18722 0.913734742327251 0.923526955388656 RPL23/BRD2 2 GO:0007269 neurotransmitter secretion 1/313 145/18722 0.914066080353154 0.923526955388656 CALM1 1 GO:0099643 signal release from synapse 1/313 145/18722 0.914066080353154 0.923526955388656 CALM1 1 GO:0031497 chromatin assembly 1/313 151/18722 0.922396641868035 0.931696475349326 BRD2 1 GO:0050871 positive regulation of B cell activation 1/313 152/18722 0.923704587110365 0.932522769326216 MIF 1 GO:0090501 RNA phosphodiester bond hydrolysis 1/313 152/18722 0.923704587110365 0.932522769326216 RPS21 1 GO:0006302 double-strand break repair 2/313 251/18722 0.924818068824706 0.933399360555582 FUS/PARP1 2 GO:0045017 glycerolipid biosynthetic process 2/313 252/18722 0.925849571725507 0.934192769562418 ABHD8/CLN3 2 GO:0051168 nuclear export 1/313 154/18722 0.926254920131333 0.934354128494961 SSB 1 GO:0001764 neuron migration 1/313 156/18722 0.928720266230905 0.936592861865181 NRP2 1 GO:0006260 DNA replication 2/313 260/18722 0.933634656256648 0.941299559419772 JUN/PTMS 2 GO:0090305 nucleic acid phosphodiester bond hydrolysis 2/313 261/18722 0.934551680626204 0.941974648701075 RPS21/N4BP2 2 GO:0010976 positive regulation of neuron projection development 1/313 163/18722 0.936719631842278 0.943909909588024 RGS2 1 GO:0002443 leukocyte mediated immunity 4/313 440/18722 0.938696869678708 0.945652019811283 SERPINB9/PRDX1/CTSC/CLU 4 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3/313 356/18722 0.939074597445101 0.945782273141138 ANXA1/CTSC/CLU 3 GO:0009451 RNA modification 1/313 167/18722 0.940882102068415 0.947101576566487 SSB 1 GO:0034728 nucleosome organization 1/313 167/18722 0.940882102068415 0.947101576566487 BRD2 1 GO:0002706 regulation of lymphocyte mediated immunity 1/313 168/18722 0.941879348204367 0.947604301959308 SERPINB9 1 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1/313 168/18722 0.941879348204367 0.947604301959308 ANXA1 1 GO:0003341 cilium movement 1/313 175/18722 0.9484059432407 0.953918474482786 CCSAP 1 GO:0006333 chromatin assembly or disassembly 1/313 177/18722 0.950132702574211 0.955402852271532 BRD2 1 GO:0006399 tRNA metabolic process 1/313 179/18722 0.951801848874395 0.956575934177619 SSB 1 GO:0007416 synapse assembly 1/313 179/18722 0.951801848874395 0.956575934177619 RAB17 1 GO:0006520 cellular amino acid metabolic process 2/313 284/18722 0.95261055119058 0.956888363634574 SERINC5/CLN3 2 GO:0007033 vacuole organization 1/313 180/18722 0.952615418485694 0.956888363634574 CLN3 1 GO:0002819 regulation of adaptive immune response 1/313 183/18722 0.954974904007893 0.959005396876299 ANXA1 1 GO:0002285 lymphocyte activation involved in immune response 1/313 194/18722 0.962667404149745 0.966475423944641 ANXA1 1 GO:0065004 protein-DNA complex assembly 1/313 201/18722 0.966865214531895 0.97043392347032 BRD2 1 GO:0016064 immunoglobulin mediated immune response 1/313 207/18722 0.970086654068221 0.973410619936141 CLU 1 GO:0006959 humoral immune response 2/313 317/18722 0.970435550897994 0.973504121809925 GAPDH/CLU 2 GO:0019724 B cell mediated immunity 1/313 210/18722 0.971578305684828 0.974393732808783 CLU 1 GO:0007601 visual perception 1/313 215/18722 0.973901421973134 0.976466345391551 TIMP3 1 GO:0002831 regulation of response to biotic stimulus 2/313 327/18722 0.974420128657453 0.976729181095029 HTRA1/SERPINB9 2 GO:0070374 positive regulation of ERK1 and ERK2 cascade 1/313 217/18722 0.974776765782343 0.9768294675792 MIF 1 GO:0045088 regulation of innate immune response 1/313 218/18722 0.97520340033031 0.976999827646708 SERPINB9 1 GO:0050953 sensory perception of light stimulus 1/313 219/18722 0.975622841299647 0.977162893140688 TIMP3 1 GO:0002703 regulation of leukocyte mediated immunity 1/313 226/18722 0.978367413306855 0.979654061667332 SERPINB9 1 GO:0016197 endosomal transport 1/313 230/18722 0.979795090229413 0.980825639890448 RAB17 1 GO:0000209 protein polyubiquitination 1/313 236/18722 0.981762408747915 0.982536669322638 DDA1 1 GO:0002366 leukocyte activation involved in immune response 1/313 275/18722 0.990636662808848 0.991157365391139 ANXA1 1 GO:0002263 cell activation involved in immune response 1/313 279/18722 0.991256210787676 0.99151665645525 ANXA1 1 GO:0007608 sensory perception of smell 1/313 456/18722 0.999583561836169 0.999583561836169 B3GNT2 1