ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	Count
GO:0001819	positive regulation of cytokine production	106/1068	467/18722	8.07334662941375e-36	4.35637784123166e-32	HLA-DPA1/CD74/HLA-DPB1/TYROBP/HLA-A/FCER1G/LAPTM5/B2M/CYBA/TREM2/C3/AIF1/CD81/CCL3/LY96/HLA-E/CD84/ISG15/SORL1/CD14/PYCARD/IFI16/C5AR1/STAT1/CD86/HMOX1/CYBB/HAVCR2/CLEC7A/CSF1R/IL18/CD83/SLC11A1/C3AR1/LGALS9/CD36/HIF1A/HLA-F/PTPRC/HGF/IFNGR1/CD4/MNDA/LPL/TLR7/SYK/TLR2/OAS1/ATP6AP2/GPSM3/HSPA1A/OAS2/LILRB1/IRF8/PTGER4/MBP/TNFRSF14/CASP1/TLR4/P2RX7/TLR1/POU2F2/CD58/AGPAT2/TGFB1/HPSE/IRF7/LILRB2/SCIMP/PTAFR/RSAD2/RUNX1/IRAK1/TLR5/JAK2/ADAM8/GBP5/SASH3/OAS3/IL6R/TLR8/LILRA2/SPN/IRAK3/LRRK2/FGR/MYD88/DENND1B/IFIH1/ARHGEF2/LACC1/PTPRJ/IL1B/STAT3/EIF2AK2/RGCC/LRP1/CEBPB/RNF135/IRF1/ADAM17/TMED10/FLOT1/EGR1/APPL1/PIK3R1	106
GO:0002683	negative regulation of immune system process	96/1068	434/18722	1.60622886008753e-31	4.33360546451616e-28	HLA-DRB1/CD74/GPNMB/TYROBP/HLA-A/HLA-B/CD68/LAPTM5/GPX1/TREM2/MAFB/CCL3/C1QC/GRN/HLA-E/BST2/CD84/ISG15/SAMHD1/DUSP1/IFI16/CD86/HMOX1/SPI1/LGALS3/ID2/HAVCR2/LST1/A2M/TMEM176B/LGALS9/LILRB4/HLA-F/FGL2/NCKAP1L/PTPRC/ARRB2/GBP1/LYN/TMEM176A/SAMSN1/MNDA/SYK/IL4I1/TMBIM6/CD300A/OAS1/AXL/LILRB1/AHR/PTGER4/TNFRSF14/HLA-DOA/TLR4/PRNP/STAT2/TGFB1/HCK/LILRB3/LILRB2/PAG1/MILR1/RUNX1/PTPN6/BTK/GPR137B/LPXN/CD300LF/VSIG4/NR1H3/OAS3/RIN3/RHBDF2/BCL6/TNFAIP8L2/TSC22D3/SPN/INPP5D/IRAK3/FGR/STAT6/PARP14/PTPRJ/SERPING1/TNFAIP3/CEBPB/ATM/HTRA1/ADAR/PRKAR1A/DUSP3/IRF1/APPL1/PIK3R1/SOCS6/PCBP2	96
GO:0042110	T cell activation	102/1068	487/18722	2.41101638453289e-31	4.33661480364649e-28	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/GPNMB/LGALS1/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/FCER1G/LAPTM5/B2M/AIF1/CD81/MAFB/HLA-DMB/HLA-E/CD84/CD44/HLA-DQA2/APBB1IP/ZFP36L2/TNFSF13B/PYCARD/CD86/SPI1/LGALS3/LCP1/HAVCR2/CLEC7A/IL18/CD83/MSN/SLC11A1/LGALS9/LILRB4/ZFP36L1/FGL2/NCKAP1L/PTPRC/LYN/GPR183/CD4/RHOA/SYK/IL4I1/CD300A/SIRPA/CORO1A/DOCK2/CD48/LILRB1/PTGER4/TNFRSF1B/TNFRSF14/HLA-DOA/ZMIZ1/PRNP/WAS/PREX1/SLAMF7/TGFBR2/TCIRG1/LILRB2/PAG1/RSAD2/CSK/PRDM1/RUNX1/PTPN6/HLA-DRB5/ADAM8/VSIG4/SASH3/IL6R/BCL6/TNFAIP8L2/LFNG/CLEC4A/SPN/ITGAL/MAP3K8/STAT6/RAB29/MR1/IL1B/STAT3/PSMB10/AZI2/CEBPB/PRKAR1A/DUSP3/IRF1/HSPH1/ADAM17/NFKBIZ/GSN/BAX/EGR1/SOCS6	102
GO:0002764	immune response-regulating signaling pathway	97/1068	468/18722	1.87782223662674e-29	2.53318219720948e-26	HLA-DRB1/HLA-DPB1/HLA-DQB1/TYROBP/HLA-A/FCER1G/LAPTM5/CYBA/TREM2/CD81/CTSS/FPR3/LY96/CTSH/CD14/C5AR1/LGALS3/HAVCR2/CLEC7A/C3AR1/LILRB4/CD36/MEF2C/NCKAP1L/PTPRC/ARRB2/GBP1/SLC15A3/LYN/MNDA/PLSCR1/TLR7/LCP2/SYK/CMTM3/LAT2/CD300A/TLR2/OAS1/HSPA1A/FPR1/FCGR1B/LILRB1/RAP1A/TLR4/PRNP/TLR1/PIK3AP1/UNC93B1/THEMIS2/HCK/IRF7/LILRB2/SCIMP/RSAD2/CSK/IFI35/IRAK1/PTPN6/BTK/TLR5/LPXN/CD300LF/KLHL6/NR1H3/OAS3/MYO1G/TLR8/LILRA2/INPP5D/IRAK3/CD33/FGR/MYD88/MAPKAPK3/DENND1B/IFIH1/LACC1/RAB29/PTPRJ/TNFAIP3/NINJ1/NFKBIA/RNF135/RPS6KA3/DUSP3/IRF1/RTN4/PAK2/NFKBIZ/PAK1/PJA2/BAX/XIAP/WNK1/FLOT1/APPL1	97
GO:0002274	myeloid leukocyte activation	62/1068	223/18722	2.19481283138506e-26	2.36864200763076e-23	CD74/TYROBP/FCER1G/TREM2/AIF1/C1QA/CCL3/GRN/HAMP/ITGB2/CD84/PYCARD/C5AR1/HMOX1/SPI1/HAVCR2/CTSC/IL18/SLC11A1/LGALS9/IFNGR2/LILRB4/PTPRC/LYN/IFNGR1/PLSCR1/LCP2/SYK/LAT2/CD300A/TLR2/DOCK2/TLR4/TLR1/PREX1/TGFBR2/PTAFR/IFI35/MILR1/ITGAM/BTK/JAK2/NOTCH2/GPR137B/CD300LF/VSIG4/NR1H3/NAMPT/ADGRE2/LILRA2/CD33/LRRK2/FGR/MYD88/KMT2E/ADAM9/STXBP2/STX4/CEBPA/PJA2/ADAM10/LTBR	62
GO:0002443	leukocyte mediated immunity	89/1068	440/18722	2.82938712824971e-26	2.54456215733924e-23	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/HLA-DQB1/TYROBP/HLA-DQA1/HLA-A/HLA-DMA/HLA-B/FCER1G/B2M/C1QB/TREM2/C3/C1QA/CD81/HLA-DMB/CCL3/C1QC/CTSH/HLA-E/BST2/ITGB2/CD84/HLA-DQA2/HMOX1/SPI1/HAVCR2/CTSC/CLEC7A/IL18/LGALS9/GAPT/LILRB4/HLA-F/NCKAP1L/PTPRC/ARRB2/LYN/SYK/LAT2/IL4I1/CD300A/CORO1A/LILRB1/AHR/TNFRSF1B/HLA-DOA/TLR4/WAS/SLAMF7/C2/TGFB1/TREM1/TCIRG1/IRF7/SCIMP/PTAFR/RSAD2/MILR1/ITGAM/PTPN6/BTK/HLA-DRB5/SASH3/MYO1G/BCL6/TLR8/ADGRE2/INPP5D/FGR/MYD88/DENND1B/STAT6/KMT2E/ERCC1/MR1/HPRT1/STXBP2/IL1B/SERPING1/STX4/ARL8B/ADAM17/LAMP1/STX7/KIF5B	89
GO:0007159	leukocyte cell-cell adhesion	80/1068	371/18722	1.29826973989644e-25	1.00078050235446e-22	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/GPNMB/LGALS1/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/LAPTM5/B2M/AIF1/CD81/HLA-DMB/HLA-E/ITGB2/CD44/HLA-DQA2/OLR1/TNFSF13B/PYCARD/CD86/LGALS3/HAVCR2/IL18/CD83/MSN/LGALS9/LILRB4/FGL2/NCKAP1L/PTPRC/LYN/PECAM1/CD4/RHOA/SYK/FERMT3/IL4I1/CD300A/SIRPA/CORO1A/LILRB1/ALOX5/TNFRSF14/HLA-DOA/ZMIZ1/KLF4/PRNP/TGFBR2/LILRB2/PAG1/PTAFR/CSK/RUNX1/IRAK1/PTPN6/HLA-DRB5/ADAM8/SELPLG/VSIG4/SASH3/ITGA4/BCL6/TNFAIP8L2/SPN/ITGAL/MAP3K8/IL1B/CEBPB/PRKAR1A/DUSP3/IRF1/HSPH1/ROCK1/NFKBIZ/WNK1/SOCS6	80
GO:0002263	cell activation involved in immune response	68/1068	279/18722	3.70090473571622e-25	2.49626024424059e-22	HLA-DRA/HLA-DRB1/CD74/LGALS1/TYROBP/FCER1G/TREM2/CD81/HLA-DMB/CCL3/GRN/ITGB2/CD84/APBB1IP/PYCARD/CD86/HMOX1/SPI1/LGALS3/LCP1/HAVCR2/CLEC7A/IL18/SLC11A1/LGALS9/GAPT/HLA-F/FGL2/NCKAP1L/PTPRC/LYN/GPR183/DOCK10/SYK/LAT2/CD300A/CORO1A/DOCK2/LILRB1/IRF8/PTGER4/TLR4/CD180/TGFB1/PTAFR/IFI35/MILR1/ITGAM/BTK/NOTCH2/IL6R/BCL6/ADGRE2/LFNG/LILRA2/SPN/ITGAL/FGR/MYD88/PTK2B/STAT6/ERCC1/STXBP2/STAT3/LRP1/STX4/NFKBIZ/LAMP1	68
GO:0002366	leukocyte activation involved in immune response	67/1068	275/18722	8.56323217484001e-25	5.13413342393741e-22	HLA-DRA/HLA-DRB1/CD74/LGALS1/TYROBP/FCER1G/TREM2/CD81/HLA-DMB/CCL3/GRN/ITGB2/CD84/APBB1IP/PYCARD/CD86/HMOX1/SPI1/LGALS3/LCP1/HAVCR2/CLEC7A/IL18/SLC11A1/LGALS9/GAPT/HLA-F/FGL2/NCKAP1L/PTPRC/LYN/GPR183/DOCK10/SYK/LAT2/CD300A/CORO1A/DOCK2/LILRB1/IRF8/PTGER4/TLR4/CD180/TGFB1/PTAFR/IFI35/MILR1/ITGAM/BTK/NOTCH2/IL6R/BCL6/ADGRE2/LFNG/LILRA2/SPN/ITGAL/FGR/MYD88/PTK2B/STAT6/ERCC1/STXBP2/STAT3/STX4/NFKBIZ/LAMP1	67
GO:1903131	mononuclear cell differentiation	85/1068	426/18722	1.05197084826459e-24	5.67643469723571e-22	HLA-DRA/HLA-DRB1/CD74/LGALS1/HLA-B/FCER1G/B2M/TREM2/MAFB/ZFP36L2/TNFSF13B/IFI16/CD86/SPI1/KLF6/ID2/CSF1R/IL18/CD83/TMEM176B/LGALS9/JUN/LILRB4/ZFP36L1/FGL2/NCKAP1L/PTPRC/LYN/GPR183/CD4/TMEM176A/DOCK10/RHOA/SYK/IL4I1/AXL/DOCK2/LILRB1/IRF8/PTGER4/HLA-DOA/ZMIZ1/VEGFA/PREX1/TGFBR2/TCIRG1/IRF7/LYL1/LILRB2/RSAD2/PRDM1/RUNX1/PTPN6/BTK/NOTCH2/CMTM7/ADAM8/SASH3/IKZF1/TRPM2/IL6R/ITGA4/BCL6/LFNG/SPN/INPP5D/PTK2B/STAT6/MR1/PTPRJ/IL1B/STAT3/AZI2/CEBPB/ATM/IRF1/ADAM17/NFKBIZ/PPP2R3C/FNIP1/IRF2BP2/BAX/LTBR/EGR1/PIK3R1	85
GO:0022407	regulation of cell-cell adhesion	87/1068	448/18722	2.07200950801375e-24	1.01641484593111e-21	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/GPNMB/LGALS1/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/LAPTM5/B2M/CD9/AIF1/CD81/HLA-DMB/PLAUR/HLA-E/FXYD5/ITGB2/CD44/HLA-DQA2/TNFSF13B/PYCARD/CD86/SPI1/LGALS3/HAVCR2/IL18/CD83/LGALS9/LILRB4/FGL2/NCKAP1L/PTPRC/LYN/CD4/RHOA/SYK/FERMT3/IL4I1/CD300A/SIRPA/CORO1A/LILRB1/MBP/ALOX5/TNFRSF14/HLA-DOA/JAK1/ZMIZ1/KLF4/PRNP/VEGFA/TGFB1/TGFBR2/LILRB2/PAG1/PTAFR/CSK/RUNX1/IRAK1/PTPN6/MYADM/HLA-DRB5/JAK2/ADAM8/VSIG4/SASH3/SH2B3/ITGA4/BCL6/TNFAIP8L2/SPN/MAP3K8/IL1B/RGCC/CEBPB/PRKAR1A/DUSP3/IRF1/HSPH1/NFKBIZ/WNK1/FLOT1/SOCS6	87
GO:0030099	myeloid cell differentiation	79/1068	381/18722	3.83292061336381e-24	1.72353663580926e-21	HLA-DRB1/CD74/TYROBP/B2M/TREM2/CD81/MAFB/CCL3/C1QC/ISG15/SNX10/FOS/IFI16/DNASE2/STAT1/ZFP36/SPI1/ID2/CSF1R/EVI2B/JUN/LILRB4/JUNB/HIF1A/MEF2C/ZFP36L1/NCKAP1L/LYN/RB1/GPR183/CD4/TLR2/CIB1/HSPA1A/LILRB1/IRF8/OSCAR/TLR4/VEGFA/CCR1/TGFB1/LILRB3/TGFBR2/TCIRG1/IRF7/RUNX1/PTPN6/JAK2/NOTCH2/GPR137B/RASSF2/KLF2/MITF/IKZF1/SH2B3/BCL6/INPP5D/FLI1/PTK2B/KMT2E/ABI1/PRKX/STAT3/ATP6AP1/NFKBIA/CEBPB/ARID4A/ADAR/PABPC4/OSTM1/SMAP1/CEBPA/ZNF385A/HCLS1/KLF10/PTBP3/CDC42/LTBR/PIK3R1	79
GO:0019882	antigen processing and presentation	41/1068	106/18722	5.58138165637544e-24	2.3167027244463e-21	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/CTSD/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/HLA-B/CD68/HLA-C/FCER1G/B2M/TREM2/HLA-DMB/CTSS/CTSH/HLA-E/HLA-DQA2/LGMN/PYCARD/IFI30/SLC11A1/RAB32/PSMB8/HLA-F/FGL2/HLA-DOA/TAPBP/TAP1/WAS/LILRB2/HLA-DRB5/CLEC4A/ERAP2/MR1/RAB8B/ARL8B/RAB10	41
GO:1903037	regulation of leukocyte cell-cell adhesion	73/1068	336/18722	1.15399111240613e-23	4.44781145895963e-21	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/GPNMB/LGALS1/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/LAPTM5/B2M/AIF1/CD81/HLA-DMB/HLA-E/ITGB2/CD44/HLA-DQA2/TNFSF13B/PYCARD/CD86/LGALS3/HAVCR2/IL18/CD83/LGALS9/LILRB4/FGL2/NCKAP1L/PTPRC/LYN/CD4/RHOA/SYK/IL4I1/CD300A/SIRPA/CORO1A/LILRB1/ALOX5/TNFRSF14/HLA-DOA/ZMIZ1/KLF4/PRNP/TGFBR2/LILRB2/PAG1/PTAFR/CSK/RUNX1/IRAK1/PTPN6/HLA-DRB5/ADAM8/VSIG4/SASH3/ITGA4/BCL6/TNFAIP8L2/SPN/MAP3K8/IL1B/CEBPB/PRKAR1A/DUSP3/IRF1/HSPH1/NFKBIZ/WNK1/SOCS6	73
GO:0050867	positive regulation of cell activation	82/1068	420/18722	3.24274605894086e-23	1.16652384893633e-20	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/LGALS1/HLA-DQB1/TYROBP/HLA-DQA1/HLA-A/HLA-DMA/B2M/TREM2/AIF1/CD81/HLA-DMB/CCL3/HAMP/HLA-E/ITGB2/PLEK/HLA-DQA2/TNFSF13B/PYCARD/CD86/HAVCR2/CTSC/CLEC7A/IL18/CD83/LGALS9/LILRB4/HLA-F/MEF2C/NCKAP1L/PTPRC/LYN/GPR183/CD4/RHOA/SYK/IL4I1/AXL/SIRPA/CORO1A/LILRB1/TNFRSF14/HLA-DOA/TLR4/ZMIZ1/TGFB1/TGFBR2/LILRB2/PTAFR/CSK/ITGAM/RUNX1/PTPN6/BTK/HLA-DRB5/JAK2/ADAM8/RPS6KA1/SASH3/BCL6/LILRA2/INPP5D/LRRK2/FGR/MYD88/MAP3K8/CDKN1A/STAT6/IL1B/SH3KBP1/BST1/STX4/HSPH1/NFKBIZ/CEBPA/PPP2R3C/LAMP1	82
GO:0002697	regulation of immune effector process	72/1068	339/18722	9.74688381498752e-23	3.28713656660454e-20	HLA-DRA/HLA-DRB1/CD74/TYROBP/HLA-A/HLA-B/LAPTM5/B2M/TREM2/C3/CD81/HLA-DMB/GRN/HLA-E/BST2/ITGB2/CD84/CD86/HMOX1/SPI1/LGALS3/HAVCR2/CLEC7A/IL18/A2M/LGALS9/LILRB4/CD36/HLA-F/FGL2/NCKAP1L/PTPRC/ARRB2/LYN/SYK/IL4I1/TMBIM6/CD300A/LILRB1/AHR/TNFRSF1B/TNFRSF14/RAP1A/TLR4/WAS/TGFB1/SCIMP/PTAFR/RSAD2/ITGAM/NCF1/PTPN6/BTK/VSIG4/SASH3/BCL6/ADGRE2/IRAK3/FGR/DENND1B/STAT6/LACC1/MR1/PTPRJ/STXBP2/IL1B/SERPING1/STX4/NFKBIZ/LAMP1/STX7/APPL1	72
GO:1903706	regulation of hemopoiesis	75/1068	367/18722	1.44579253611535e-22	4.58911560286968e-20	HLA-DRA/HLA-DRB1/CD74/TYROBP/HLA-B/B2M/TREM2/MAFB/CCL3/C1QC/ISG15/ZFP36L2/FOS/STAT1/ZFP36/CD86/SPI1/ID2/IL18/CD83/EVI2B/TMEM176B/LGALS9/JUN/LILRB4/HIF1A/MEF2C/ZFP36L1/FGL2/NCKAP1L/PTPRC/LYN/RB1/CD4/TMEM176A/RHOA/SYK/IL4I1/CIB1/AXL/HSPA1A/LILRB1/HLA-DOA/TLR4/ZMIZ1/CCR1/TGFB1/LILRB3/TGFBR2/IRF7/LILRB2/PRDM1/RUNX1/PTPN6/BTK/NOTCH2/GPR137B/ADAM8/RASSF2/MITF/SASH3/BCL6/INPP5D/PTK2B/STAT3/ATP6AP1/NFKBIA/CEBPB/IRF1/NFKBIZ/SMAP1/HCLS1/PPP2R3C/KLF10/PIK3R1	75
GO:0048002	antigen processing and presentation of peptide antigen	31/1068	62/18722	1.53745796961241e-22	4.60895733557141e-20	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/CTSD/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/HLA-B/HLA-C/FCER1G/B2M/TREM2/HLA-DMB/CTSS/HLA-E/HLA-DQA2/LGMN/PYCARD/IFI30/SLC11A1/HLA-F/HLA-DOA/TAPBP/TAP1/HLA-DRB5/CLEC4A/ERAP2/MR1	31
GO:0002831	regulation of response to biotic stimulus	70/1068	327/18722	2.42093788502938e-22	6.87546359348343e-20	APOE/HLA-DRB1/TYROBP/HLA-A/HLA-B/CYBA/TREM2/GRN/LY96/HLA-E/ISG15/SAMHD1/PYCARD/IFI16/STAT1/LY86/SPI1/HAVCR2/CLEC7A/A2M/LGALS9/CD36/HLA-F/FGL2/ARRB2/LYN/MNDA/PLSCR1/SYK/IL4I1/OAS1/IFIT1/LILRB1/AHR/TLR4/CD180/PARP9/STAT2/CARD16/HCK/IRF7/SCIMP/IFI35/NCF1/PTPN6/DTX3L/ADAM8/GBP5/VSIG4/NR1H3/OAS3/TLR8/LILRA2/IRAK3/FGR/PARP14/MR1/SERPING1/TNFAIP3/RNF135/HTRA1/ADAR/IRF1/PAK2/PAK1/PPP2R3C/LAMP1/XIAP/APPL1/PCBP2	70
GO:0032103	positive regulation of response to external stimulus	81/1068	427/18722	4.16409026055838e-22	1.12347155229865e-19	CD74/TYROBP/TMSB4X/CYBA/TREM2/C3/AIF1/CD81/CCL3/GRN/CXCR4/NUPR1/LY96/HLA-E/LGMN/ALOX5AP/PYCARD/IFI16/C5AR1/LY86/SPI1/HAVCR2/CTSC/CLEC7A/CSF1R/IL18/C3AR1/LGALS9/HLA-F/PLA2G7/NCKAP1L/NEAT1/LYN/FLNA/MNDA/LPL/PLSCR1/CCL4/TLR7/SYK/TLR2/GPSM3/PTGER4/TLR4/CD180/PARP9/VEGFA/CCR1/TGFB1/HCK/IRF7/SCIMP/IFI35/BTK/CAMK1D/JAK2/ADAM8/GBP5/IL6R/TLR8/LILRA2/LRRK2/PTK2B/MGST2/IL1B/RAC1/NINJ1/LRP1/NFKBIA/CEBPB/VEGFB/STX4/TNFRSF1A/PAK2/ADAM17/NFKBIZ/CEBPA/PAK1/ADAM10/LAMP1/WNK1	81
GO:0045785	positive regulation of cell adhesion	82/1068	437/18722	4.73142724173401e-22	1.21575149506651e-19	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/LGALS1/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/B2M/AIF1/CD81/HLA-DMB/PLAUR/HLA-E/ITGB2/LIMS1/CD44/HLA-DQA2/APBB1IP/TNFSF13B/PYCARD/CD86/HAVCR2/IL18/CD83/LGALS9/LILRB4/CD36/NCKAP1L/PTPRC/LYN/CD4/FLNA/RHOA/SYK/IL4I1/CIB1/SIRPA/CORO1A/LILRB1/ALOX5/TNFRSF14/HLA-DOA/JAK1/ZMIZ1/VEGFA/PREX1/TGFBR2/LILRB2/PTAFR/CSK/RUNX1/IRAK1/PTPN6/MYADM/HLA-DRB5/PLEKHA2/JAK2/RIN2/ADAM8/SASH3/ITGA4/BCL6/RRAS/STK4/PTK2B/MAP3K8/ADAM9/PTPRJ/IL1B/RAC1/ATM/STX4/HSPH1/IQGAP1/ROCK1/NFKBIZ/CDC42/FLOT1/S100A10	82
GO:0071706	tumor necrosis factor superfamily cytokine production	51/1068	186/18722	1.28447757997392e-21	3.01349609632142e-19	GPNMB/TYROBP/CYBA/TREM2/ACP5/CCL3/LY96/TSPO/HLA-E/CD84/CD14/PYCARD/ZFP36/CD86/CYBB/HAVCR2/CLEC7A/LGALS9/CD36/PTPRC/ARRB2/IFNGR1/LPL/SYK/TLR2/OAS1/AXL/SIRPA/OAS2/LILRB1/TLR4/TLR1/PTAFR/PTPN6/JAK2/ADAM8/SASH3/OAS3/CLEC4A/LILRA2/SPN/IRAK3/CD33/LRRK2/MYD88/IFIH1/ARHGEF2/PTPRJ/STAT3/TNFAIP3/PIK3R1	51
GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	51/1068	186/18722	1.28447757997392e-21	3.01349609632142e-19	GPNMB/TYROBP/CYBA/TREM2/ACP5/CCL3/LY96/TSPO/HLA-E/CD84/CD14/PYCARD/ZFP36/CD86/CYBB/HAVCR2/CLEC7A/LGALS9/CD36/PTPRC/ARRB2/IFNGR1/LPL/SYK/TLR2/OAS1/AXL/SIRPA/OAS2/LILRB1/TLR4/TLR1/PTAFR/PTPN6/JAK2/ADAM8/SASH3/OAS3/CLEC4A/LILRA2/SPN/IRAK3/CD33/LRRK2/MYD88/IFIH1/ARHGEF2/PTPRJ/STAT3/TNFAIP3/PIK3R1	51
GO:0002696	positive regulation of leukocyte activation	78/1068	409/18722	1.79608096000833e-21	4.03818869175205e-19	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/LGALS1/HLA-DQB1/TYROBP/HLA-DQA1/HLA-A/HLA-DMA/B2M/TREM2/AIF1/CD81/HLA-DMB/CCL3/HAMP/HLA-E/ITGB2/HLA-DQA2/TNFSF13B/PYCARD/CD86/HAVCR2/CTSC/CLEC7A/IL18/CD83/LGALS9/LILRB4/HLA-F/MEF2C/NCKAP1L/PTPRC/LYN/GPR183/CD4/RHOA/SYK/IL4I1/AXL/SIRPA/CORO1A/LILRB1/TNFRSF14/HLA-DOA/TLR4/ZMIZ1/TGFB1/TGFBR2/LILRB2/PTAFR/CSK/ITGAM/RUNX1/PTPN6/BTK/HLA-DRB5/ADAM8/SASH3/BCL6/INPP5D/LRRK2/FGR/MYD88/MAP3K8/CDKN1A/STAT6/IL1B/SH3KBP1/BST1/STX4/HSPH1/NFKBIZ/CEBPA/PPP2R3C/LAMP1	78
GO:0050866	negative regulation of cell activation	54/1068	210/18722	2.20114954901157e-21	4.75096118658656e-19	APOE/HLA-DRB1/CD74/GPNMB/TYROBP/LAPTM5/TREM2/CD9/GRN/CD84/CD86/HMOX1/SPI1/LGALS3/ID2/HAVCR2/LST1/LGALS9/LILRB4/HLA-F/FGL2/NCKAP1L/PTPRC/LYN/SAMSN1/MNDA/IL4I1/CD300A/AXL/LILRB1/TNFRSF14/PRNP/LILRB2/PAG1/MILR1/RUNX1/PTPN6/BTK/CD300LF/VSIG4/NR1H3/SH2B3/BCL6/TNFAIP8L2/SPN/INPP5D/FGR/TNFAIP3/CEBPB/ATM/PRKAR1A/DUSP3/IRF1/SOCS6	54
GO:0070661	leukocyte proliferation	67/1068	318/18722	4.94664930281052e-21	1.0266199860756e-18	HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/GPNMB/TYROBP/HLA-A/TREM2/AIF1/CD81/HLA-DMB/HLA-E/BST2/TNFSF13B/PYCARD/CD86/LGALS3/HAVCR2/LST1/CSF1R/IL18/MSN/SLC11A1/LGALS9/GAPT/LILRB4/MEF2C/NCKAP1L/PTPRC/LYN/GPR183/MNDA/SYK/IL4I1/CD300A/CORO1A/DOCK2/LILRB1/AHR/TNFRSF1B/TNFRSF14/TLR4/CD180/PRNP/TGFBR2/TCIRG1/LILRB2/PTPN6/BTK/VSIG4/SASH3/BCL6/SPN/INPP5D/MYD88/CDKN1A/HPRT1/IL1B/PSMB10/TNFAIP3/AZI2/BST1/CEBPB/ATM/PRKAR1A/IRF1/BAX	67
GO:0019221	cytokine-mediated signaling pathway	84/1068	472/18722	5.17633316408671e-21	1.03449976864489e-18	CD74/TMSB4X/FCER1G/LAPTM5/TREM2/IFI27/CCL3/CCL3L3/CXCR4/ISG15/LIMS1/CD44/SAMHD1/TNFSF13B/PYCARD/STAT1/SPI1/CSF1R/IL18/MX1/IFITM3/IFNGR2/LILRB4/HIF1A/PTPRC/IFNGR1/CD4/IL13RA1/CCL4/SYK/CIB1/OAS1/AXL/HSPA1A/OAS2/LILRB1/TNFRSF1B/TNFRSF14/IL10RA/CASP1/JAK1/PARP9/CCR1/SP100/PLP2/STAT2/CARD16/AGPAT2/HCK/LILRB3/IRF7/LILRB2/IRAK1/PTPN6/CCRL2/JAK2/CD300LF/NR1H3/OAS3/IL6R/SH2B3/STAT5A/DOK1/LILRA2/IRAK3/MYD88/ACSL1/PTK2B/STAT6/IFNAR1/PARP14/PTPRJ/IL1B/STAT3/TNFAIP3/NFKBIA/ADAR/IRF1/TNFRSF1A/ADAM17/CEBPA/WNK1/EGR1/APPL1	84
GO:1902105	regulation of leukocyte differentiation	62/1068	279/18722	8.49138041068128e-21	1.63012647043574e-18	HLA-DRA/HLA-DRB1/CD74/TYROBP/HLA-B/TREM2/MAFB/CCL3/C1QC/ZFP36L2/FOS/CD86/ID2/IL18/CD83/EVI2B/TMEM176B/LGALS9/JUN/LILRB4/ZFP36L1/FGL2/NCKAP1L/PTPRC/LYN/RB1/CD4/TMEM176A/RHOA/SYK/IL4I1/AXL/LILRB1/HLA-DOA/TLR4/ZMIZ1/CCR1/TGFB1/LILRB3/TGFBR2/IRF7/LILRB2/PRDM1/RUNX1/PTPN6/BTK/NOTCH2/GPR137B/ADAM8/RASSF2/MITF/SASH3/BCL6/INPP5D/ATP6AP1/CEBPB/IRF1/NFKBIZ/HCLS1/PPP2R3C/KLF10/PIK3R1	62
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	71/1068	356/18722	8.76087243191929e-21	1.63012647043574e-18	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/HLA-B/FCER1G/B2M/C1QB/TREM2/C3/C1QA/CD81/HLA-DMB/C1QC/CTSH/HLA-E/HLA-DQA2/TNFSF13B/HAVCR2/CTSC/CLEC7A/IL18/SLC11A1/GAPT/LILRB4/HLA-F/MEF2C/NCKAP1L/PTPRC/CD4/IL4I1/LILRB1/AHR/TNFRSF1B/HLA-DOA/TLR4/WAS/C2/TGFB1/TCIRG1/IRF7/RSAD2/PTPN6/BTK/HLA-DRB5/KLHL6/SASH3/IL6R/MYO1G/BCL6/TLR8/SPN/INPP5D/MYD88/DENND1B/STAT6/ERCC1/MR1/HPRT1/IL1B/STAT3/SERPING1/TNFAIP3/ADAM17/NFKBIZ/STX7	71
GO:0002695	negative regulation of leukocyte activation	50/1068	187/18722	1.07608201122126e-20	1.93551284418331e-18	HLA-DRB1/CD74/GPNMB/TYROBP/LAPTM5/GRN/CD84/CD86/HMOX1/SPI1/LGALS3/ID2/HAVCR2/LST1/LGALS9/LILRB4/HLA-F/FGL2/NCKAP1L/PTPRC/LYN/SAMSN1/MNDA/IL4I1/CD300A/AXL/LILRB1/TNFRSF14/PRNP/LILRB2/PAG1/MILR1/RUNX1/PTPN6/BTK/CD300LF/VSIG4/NR1H3/BCL6/TNFAIP8L2/SPN/INPP5D/FGR/TNFAIP3/CEBPB/ATM/PRKAR1A/DUSP3/IRF1/SOCS6	50
GO:0032640	tumor necrosis factor production	49/1068	181/18722	1.47156995978752e-20	2.4814348446917e-18	GPNMB/TYROBP/CYBA/TREM2/ACP5/CCL3/LY96/TSPO/HLA-E/CD84/CD14/PYCARD/ZFP36/CYBB/HAVCR2/CLEC7A/LGALS9/CD36/PTPRC/ARRB2/IFNGR1/LPL/SYK/TLR2/OAS1/AXL/SIRPA/OAS2/LILRB1/TLR4/TLR1/PTAFR/PTPN6/JAK2/SASH3/OAS3/CLEC4A/LILRA2/SPN/IRAK3/CD33/LRRK2/MYD88/IFIH1/ARHGEF2/PTPRJ/STAT3/TNFAIP3/PIK3R1	49
GO:0032680	regulation of tumor necrosis factor production	49/1068	181/18722	1.47156995978752e-20	2.4814348446917e-18	GPNMB/TYROBP/CYBA/TREM2/ACP5/CCL3/LY96/TSPO/HLA-E/CD84/CD14/PYCARD/ZFP36/CYBB/HAVCR2/CLEC7A/LGALS9/CD36/PTPRC/ARRB2/IFNGR1/LPL/SYK/TLR2/OAS1/AXL/SIRPA/OAS2/LILRB1/TLR4/TLR1/PTAFR/PTPN6/JAK2/SASH3/OAS3/CLEC4A/LILRA2/SPN/IRAK3/CD33/LRRK2/MYD88/IFIH1/ARHGEF2/PTPRJ/STAT3/TNFAIP3/PIK3R1	49
GO:0002224	toll-like receptor signaling pathway	40/1068	121/18722	1.7246020773628e-20	2.81998569983323e-18	CYBA/TREM2/CTSS/LY96/CD14/HAVCR2/CD36/ARRB2/LYN/TLR7/CD300A/TLR2/OAS1/TLR4/TLR1/PIK3AP1/UNC93B1/IRF7/SCIMP/RSAD2/IFI35/IRAK1/BTK/TLR5/CD300LF/NR1H3/TLR8/LILRA2/IRAK3/MYD88/MAPKAPK3/TNFAIP3/NINJ1/NFKBIA/RPS6KA3/IRF1/RTN4/PJA2/FLOT1/APPL1	40
GO:0034341	response to interferon-gamma	43/1068	141/18722	2.19147892142843e-20	3.4780059588317e-18	HLA-DPA1/CD74/VIM/AIF1/CCL3/CCL3L3/BST2/CXCL16/STAT1/IFITM3/SLC11A1/LGALS9/IFNGR2/GBP1/ACTR2/IFNGR1/ACTR3/CCL4/TLR2/GBP4/SIRPA/IRF8/ZYX/CASP1/TLR4/JAK1/GBP2/PARP9/WAS/CIITA/SP100/KYNU/CD58/HCK/JAK2/GBP5/NR1H3/PARP14/DAPK1/STX4/IRF1/CDC42/KIF5B	43
GO:0050863	regulation of T cell activation	67/1068	329/18722	3.46024197150229e-20	5.33470447949325e-18	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/GPNMB/LGALS1/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/LAPTM5/B2M/AIF1/CD81/HLA-DMB/HLA-E/HLA-DQA2/TNFSF13B/PYCARD/CD86/LGALS3/HAVCR2/IL18/CD83/LGALS9/LILRB4/FGL2/NCKAP1L/PTPRC/LYN/CD4/RHOA/SYK/IL4I1/CD300A/SIRPA/CORO1A/LILRB1/TNFRSF1B/TNFRSF14/HLA-DOA/ZMIZ1/PRNP/TGFBR2/LILRB2/PAG1/CSK/PRDM1/RUNX1/PTPN6/HLA-DRB5/ADAM8/VSIG4/SASH3/BCL6/TNFAIP8L2/SPN/MAP3K8/IL1B/CEBPB/PRKAR1A/DUSP3/IRF1/HSPH1/NFKBIZ/SOCS6	67
GO:0046651	lymphocyte proliferation	62/1068	288/18722	4.75309409734526e-20	6.93457280094344e-18	HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/GPNMB/TYROBP/HLA-A/AIF1/CD81/HLA-DMB/HLA-E/TNFSF13B/PYCARD/CD86/LGALS3/HAVCR2/LST1/IL18/MSN/SLC11A1/LGALS9/GAPT/LILRB4/MEF2C/NCKAP1L/PTPRC/LYN/GPR183/MNDA/SYK/IL4I1/CD300A/CORO1A/DOCK2/LILRB1/AHR/TNFRSF1B/TNFRSF14/TLR4/CD180/PRNP/TGFBR2/LILRB2/PTPN6/BTK/VSIG4/SASH3/BCL6/SPN/INPP5D/MYD88/CDKN1A/HPRT1/IL1B/PSMB10/AZI2/BST1/CEBPB/ATM/PRKAR1A/IRF1/BAX	62
GO:1903039	positive regulation of leukocyte cell-cell adhesion	56/1068	239/18722	4.75498876269287e-20	6.93457280094344e-18	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/LGALS1/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/B2M/AIF1/CD81/HLA-DMB/HLA-E/ITGB2/CD44/HLA-DQA2/TNFSF13B/PYCARD/CD86/HAVCR2/IL18/CD83/LGALS9/LILRB4/NCKAP1L/PTPRC/LYN/CD4/RHOA/SYK/IL4I1/SIRPA/CORO1A/LILRB1/ALOX5/TNFRSF14/HLA-DOA/ZMIZ1/TGFBR2/LILRB2/PTAFR/CSK/RUNX1/IRAK1/PTPN6/HLA-DRB5/ADAM8/SASH3/ITGA4/BCL6/MAP3K8/IL1B/HSPH1/NFKBIZ	56
GO:0002221	pattern recognition receptor signaling pathway	47/1068	172/18722	5.90924742948437e-20	8.39113134986781e-18	CYBA/TREM2/CTSS/LY96/CD14/HAVCR2/CD36/ARRB2/SLC15A3/LYN/TLR7/CD300A/TLR2/OAS1/HSPA1A/TLR4/TLR1/PIK3AP1/UNC93B1/IRF7/SCIMP/RSAD2/IFI35/IRAK1/BTK/TLR5/CD300LF/NR1H3/OAS3/TLR8/LILRA2/IRAK3/MYD88/MAPKAPK3/IFIH1/LACC1/TNFAIP3/NINJ1/NFKBIA/RNF135/RPS6KA3/IRF1/RTN4/PJA2/XIAP/FLOT1/APPL1	47
GO:0050777	negative regulation of immune response	50/1068	194/18722	6.12406105609875e-20	8.47318806633561e-18	HLA-DRB1/HLA-A/HLA-B/GPX1/TREM2/GRN/HLA-E/CD84/ISG15/SAMHD1/IFI16/HMOX1/SPI1/LGALS3/HAVCR2/A2M/LGALS9/LILRB4/HLA-F/FGL2/NCKAP1L/PTPRC/ARRB2/LYN/SAMSN1/SYK/IL4I1/CD300A/OAS1/LILRB1/AHR/TNFRSF14/STAT2/HCK/PTPN6/VSIG4/NR1H3/OAS3/RHBDF2/BCL6/INPP5D/IRAK3/FGR/STAT6/PARP14/SERPING1/TNFAIP3/HTRA1/ADAR/PCBP2	50
GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	37/1068	107/18722	8.19840574828359e-20	1.09155562448371e-17	TYROBP/CYBA/CCL3/LY96/HLA-E/CD84/CD14/PYCARD/CD86/CYBB/HAVCR2/CLEC7A/LGALS9/CD36/PTPRC/IFNGR1/LPL/SYK/TLR2/OAS1/OAS2/TLR4/TLR1/PTAFR/JAK2/ADAM8/SASH3/OAS3/LILRA2/SPN/LRRK2/MYD88/IFIH1/ARHGEF2/PTPRJ/STAT3/PIK3R1	37
GO:0032943	mononuclear cell proliferation	62/1068	291/18722	8.29388076423873e-20	1.09155562448371e-17	HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/GPNMB/TYROBP/HLA-A/AIF1/CD81/HLA-DMB/HLA-E/TNFSF13B/PYCARD/CD86/LGALS3/HAVCR2/LST1/IL18/MSN/SLC11A1/LGALS9/GAPT/LILRB4/MEF2C/NCKAP1L/PTPRC/LYN/GPR183/MNDA/SYK/IL4I1/CD300A/CORO1A/DOCK2/LILRB1/AHR/TNFRSF1B/TNFRSF14/TLR4/CD180/PRNP/TGFBR2/LILRB2/PTPN6/BTK/VSIG4/SASH3/BCL6/SPN/INPP5D/MYD88/CDKN1A/HPRT1/IL1B/PSMB10/AZI2/BST1/CEBPB/ATM/PRKAR1A/IRF1/BAX	62
GO:0002478	antigen processing and presentation of exogenous peptide antigen	23/1068	38/18722	1.33773240584792e-19	1.7186676337989e-17	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/CTSD/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/FCER1G/B2M/HLA-DMB/CTSS/HLA-E/HLA-DQA2/LGMN/IFI30/HLA-F/HLA-DOA/TAP1/HLA-DRB5/CLEC4A	23
GO:0070663	regulation of leukocyte proliferation	56/1068	245/18722	1.65159699858772e-19	2.07256218706497e-17	HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/GPNMB/TYROBP/HLA-A/AIF1/CD81/HLA-DMB/HLA-E/BST2/TNFSF13B/PYCARD/CD86/LGALS3/HAVCR2/LST1/CSF1R/IL18/LGALS9/LILRB4/MEF2C/NCKAP1L/PTPRC/LYN/GPR183/MNDA/SYK/IL4I1/CD300A/CORO1A/LILRB1/AHR/TNFRSF1B/TNFRSF14/TLR4/PRNP/TGFBR2/LILRB2/PTPN6/BTK/VSIG4/SASH3/BCL6/SPN/INPP5D/MYD88/CDKN1A/IL1B/TNFAIP3/BST1/CEBPB/ATM/PRKAR1A/IRF1	56
GO:0050670	regulation of lymphocyte proliferation	53/1068	225/18722	3.75328239525769e-19	4.60288904654784e-17	HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/GPNMB/TYROBP/HLA-A/AIF1/CD81/HLA-DMB/HLA-E/TNFSF13B/PYCARD/CD86/LGALS3/HAVCR2/LST1/IL18/LGALS9/LILRB4/MEF2C/NCKAP1L/PTPRC/LYN/GPR183/MNDA/SYK/IL4I1/CD300A/CORO1A/LILRB1/AHR/TNFRSF1B/TNFRSF14/TLR4/PRNP/TGFBR2/LILRB2/PTPN6/BTK/VSIG4/SASH3/BCL6/SPN/INPP5D/MYD88/CDKN1A/IL1B/BST1/CEBPB/ATM/PRKAR1A/IRF1	53
GO:0045088	regulation of innate immune response	52/1068	218/18722	4.5192038330768e-19	5.41902752961832e-17	APOE/TYROBP/HLA-A/HLA-B/TREM2/GRN/HLA-E/ISG15/SAMHD1/PYCARD/IFI16/SPI1/HAVCR2/CLEC7A/A2M/LGALS9/HLA-F/ARRB2/LYN/MNDA/PLSCR1/SYK/OAS1/LILRB1/TLR4/PARP9/STAT2/HCK/IRF7/IFI35/NCF1/PTPN6/ADAM8/GBP5/VSIG4/NR1H3/OAS3/TLR8/LILRA2/IRAK3/FGR/PARP14/SERPING1/TNFAIP3/RNF135/ADAR/IRF1/PAK2/PAK1/LAMP1/XIAP/APPL1	52
GO:0022409	positive regulation of cell-cell adhesion	60/1068	284/18722	5.11694469124739e-19	6.00239859868933e-17	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/LGALS1/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/B2M/AIF1/CD81/HLA-DMB/PLAUR/HLA-E/ITGB2/CD44/HLA-DQA2/TNFSF13B/PYCARD/CD86/HAVCR2/IL18/CD83/LGALS9/LILRB4/NCKAP1L/PTPRC/LYN/CD4/RHOA/SYK/IL4I1/SIRPA/CORO1A/LILRB1/ALOX5/TNFRSF14/HLA-DOA/JAK1/ZMIZ1/TGFBR2/LILRB2/PTAFR/CSK/RUNX1/IRAK1/PTPN6/HLA-DRB5/JAK2/ADAM8/SASH3/ITGA4/BCL6/MAP3K8/IL1B/HSPH1/NFKBIZ/FLOT1	60
GO:0032944	regulation of mononuclear cell proliferation	53/1068	227/18722	5.72892197597253e-19	6.5772899962442e-17	HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/GPNMB/TYROBP/HLA-A/AIF1/CD81/HLA-DMB/HLA-E/TNFSF13B/PYCARD/CD86/LGALS3/HAVCR2/LST1/IL18/LGALS9/LILRB4/MEF2C/NCKAP1L/PTPRC/LYN/GPR183/MNDA/SYK/IL4I1/CD300A/CORO1A/LILRB1/AHR/TNFRSF1B/TNFRSF14/TLR4/PRNP/TGFBR2/LILRB2/PTPN6/BTK/VSIG4/SASH3/BCL6/SPN/INPP5D/MYD88/CDKN1A/IL1B/BST1/CEBPB/ATM/PRKAR1A/IRF1	53
GO:0030098	lymphocyte differentiation	70/1068	374/18722	6.51878715982976e-19	7.32820323217529e-17	HLA-DRA/HLA-DRB1/CD74/LGALS1/FCER1G/B2M/MAFB/ZFP36L2/TNFSF13B/CD86/SPI1/KLF6/ID2/IL18/CD83/LGALS9/LILRB4/ZFP36L1/FGL2/NCKAP1L/PTPRC/GPR183/CD4/DOCK10/RHOA/SYK/IL4I1/AXL/DOCK2/IRF8/PTGER4/HLA-DOA/ZMIZ1/PREX1/TGFBR2/TCIRG1/LYL1/LILRB2/RSAD2/PRDM1/RUNX1/PTPN6/BTK/NOTCH2/CMTM7/ADAM8/SASH3/IKZF1/IL6R/ITGA4/BCL6/LFNG/SPN/INPP5D/PTK2B/STAT6/MR1/PTPRJ/IL1B/STAT3/ATM/IRF1/ADAM17/NFKBIZ/PPP2R3C/FNIP1/IRF2BP2/BAX/EGR1/PIK3R1	70
GO:0032760	positive regulation of tumor necrosis factor production	35/1068	103/18722	1.55694594325399e-18	1.7145470019997e-16	TYROBP/CYBA/CCL3/LY96/HLA-E/CD84/CD14/PYCARD/CYBB/HAVCR2/CLEC7A/LGALS9/CD36/PTPRC/IFNGR1/LPL/SYK/TLR2/OAS1/OAS2/TLR4/TLR1/PTAFR/JAK2/SASH3/OAS3/LILRA2/SPN/LRRK2/MYD88/IFIH1/ARHGEF2/PTPRJ/STAT3/PIK3R1	35
GO:0002703	regulation of leukocyte mediated immunity	52/1068	226/18722	2.44603533067464e-18	2.63976132886407e-16	HLA-DRA/HLA-DRB1/TYROBP/HLA-A/HLA-B/B2M/TREM2/C3/CD81/HLA-E/BST2/ITGB2/CD84/HMOX1/SPI1/HAVCR2/CLEC7A/IL18/LGALS9/LILRB4/HLA-F/NCKAP1L/PTPRC/ARRB2/LYN/SYK/IL4I1/CD300A/LILRB1/AHR/TNFRSF1B/TLR4/WAS/TGFB1/SCIMP/PTAFR/RSAD2/ITGAM/PTPN6/BTK/SASH3/BCL6/ADGRE2/FGR/DENND1B/STAT6/MR1/STXBP2/IL1B/STX4/LAMP1/STX7	52
GO:0050900	leukocyte migration	68/1068	369/18722	4.93519534403083e-18	5.20113340598485e-16	CD74/FCER1G/TREM2/CD9/AIF1/CD81/CCL3/CCL3L3/CXCR4/ITGB2/CXCL16/LGMN/DUSP1/PYCARD/C5AR1/HMOX1/SPI1/LGALS3/CSF1R/MSN/C3AR1/LGALS9/PLA2G7/NCKAP1L/CKLF/LYN/GPR183/PECAM1/CCL4/RHOA/SYK/CD300A/GPSM3/SIRPA/CORO1A/PTGER4/ALOX5/TNFRSF14/RHOG/VEGFA/PREX1/CCR1/TREM1/HCK/PTAFR/CAMK1D/ADAM8/SELPLG/TRPM2/RIN3/IL6R/ITGA4/MYO1G/ADGRE2/SPN/ITGAL/MYD88/PTK2B/RAC1/NINJ1/BST1/VEGFB/ROCK1/ADAM17/ADAM10/CDC42/WNK1/PLEC	68
GO:0019884	antigen processing and presentation of exogenous antigen	24/1068	47/18722	5.01221158471483e-18	5.20113340598485e-16	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/CTSD/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/FCER1G/B2M/HLA-DMB/CTSS/HLA-E/HLA-DQA2/LGMN/IFI30/HLA-F/HLA-DOA/TAP1/HLA-DRB5/CLEC4A/MR1	24
GO:0032496	response to lipopolysaccharide	65/1068	343/18722	6.27716346910258e-18	6.39086303382595e-16	VIM/CD68/TREM2/ACP5/CCL3/HAMP/LY96/TSPO/MTDH/SOD2/CD14/FOS/PYCARD/C5AR1/LITAF/ZFP36/CD86/LY86/SPI1/HAVCR2/IL18/SLC11A1/LGALS9/JUN/CD36/MEF2C/LYN/RHOA/TLR2/AXL/SIRPA/MGST1/LILRB1/IRF8/PTGER4/TNFRSF1B/IL10RA/CASP1/TLR4/CD180/CARD16/TGFB1/HCK/LILRB2/SCIMP/PTAFR/IRAK1/JAK2/NR1H3/LILRA2/IRAK3/MYD88/MAPKAPK3/IFNAR1/MGST2/ADAM9/IL1B/TNFAIP3/NFKBIA/CEBPB/ABCA1/RPS6KA3/ADAM17/TAB2/NR4A1	65
GO:0051251	positive regulation of lymphocyte activation	67/1068	362/18722	6.91526081089432e-18	6.91013839547884e-16	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/LGALS1/HLA-DQB1/TYROBP/HLA-DQA1/HLA-A/HLA-DMA/B2M/AIF1/CD81/HLA-DMB/HLA-E/HLA-DQA2/TNFSF13B/PYCARD/CD86/HAVCR2/CLEC7A/IL18/CD83/LGALS9/LILRB4/HLA-F/MEF2C/NCKAP1L/PTPRC/LYN/GPR183/CD4/RHOA/SYK/IL4I1/AXL/SIRPA/CORO1A/LILRB1/TNFRSF14/HLA-DOA/TLR4/ZMIZ1/TGFB1/TGFBR2/LILRB2/CSK/RUNX1/PTPN6/BTK/HLA-DRB5/ADAM8/SASH3/BCL6/INPP5D/MYD88/MAP3K8/CDKN1A/STAT6/IL1B/SH3KBP1/BST1/HSPH1/NFKBIZ/PPP2R3C/LAMP1	67
GO:0002237	response to molecule of bacterial origin	67/1068	363/18722	8.02726753765669e-18	7.87547920603554e-16	VIM/CD68/B2M/TREM2/ACP5/CCL3/HAMP/LY96/TSPO/MTDH/SOD2/CD14/FOS/PYCARD/C5AR1/LITAF/ZFP36/CD86/LY86/SPI1/HAVCR2/IL18/SLC11A1/LGALS9/JUN/CD36/MEF2C/LYN/RHOA/TLR2/AXL/SIRPA/MGST1/LILRB1/IRF8/PTGER4/TNFRSF1B/IL10RA/CASP1/TLR4/CD180/TLR1/CARD16/TGFB1/HCK/LILRB2/SCIMP/PTAFR/IRAK1/JAK2/NR1H3/LILRA2/IRAK3/MYD88/MAPKAPK3/IFNAR1/MGST2/ADAM9/IL1B/TNFAIP3/NFKBIA/CEBPB/ABCA1/RPS6KA3/ADAM17/TAB2/NR4A1	67
GO:0002573	myeloid leukocyte differentiation	49/1068	208/18722	8.34855573013207e-18	8.00538692583391e-16	HLA-DRB1/CD74/TYROBP/TREM2/CD81/MAFB/CCL3/C1QC/SNX10/FOS/IFI16/SPI1/ID2/CSF1R/EVI2B/JUN/LILRB4/JUNB/ZFP36L1/LYN/RB1/GPR183/CD4/TLR2/LILRB1/OSCAR/TLR4/VEGFA/CCR1/TGFB1/LILRB3/TGFBR2/TCIRG1/IRF7/RUNX1/NOTCH2/GPR137B/RASSF2/MITF/INPP5D/ATP6AP1/CEBPB/OSTM1/CEBPA/HCLS1/KLF10/CDC42/LTBR/PIK3R1	49
GO:0050870	positive regulation of T cell activation	50/1068	216/18722	8.4563946399654e-18	8.00538692583391e-16	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/LGALS1/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/B2M/AIF1/CD81/HLA-DMB/HLA-E/HLA-DQA2/TNFSF13B/PYCARD/CD86/HAVCR2/IL18/CD83/LGALS9/LILRB4/NCKAP1L/PTPRC/LYN/CD4/RHOA/SYK/IL4I1/SIRPA/CORO1A/LILRB1/TNFRSF14/HLA-DOA/ZMIZ1/TGFBR2/LILRB2/CSK/RUNX1/PTPN6/HLA-DRB5/ADAM8/SASH3/BCL6/MAP3K8/IL1B/HSPH1/NFKBIZ	50
GO:0051250	negative regulation of lymphocyte activation	42/1068	157/18722	1.3336531937405e-17	1.2407573505903e-15	HLA-DRB1/CD74/GPNMB/TYROBP/LAPTM5/CD86/LGALS3/ID2/HAVCR2/LST1/LGALS9/LILRB4/HLA-F/FGL2/NCKAP1L/LYN/SAMSN1/MNDA/IL4I1/CD300A/AXL/LILRB1/TNFRSF14/PRNP/LILRB2/PAG1/RUNX1/PTPN6/BTK/VSIG4/BCL6/TNFAIP8L2/SPN/INPP5D/FGR/TNFAIP3/CEBPB/ATM/PRKAR1A/DUSP3/IRF1/SOCS6	42
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	21/1068	36/18722	1.54029993096091e-17	1.40475648146568e-15	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/CTSD/HLA-DQB1/HLA-DQA1/HLA-DMA/FCER1G/B2M/TREM2/HLA-DMB/CTSS/HLA-DQA2/LGMN/PYCARD/IFI30/HLA-DOA/HLA-DRB5/ARL8B	21
GO:0032635	interleukin-6 production	43/1068	165/18722	1.5880308630357e-17	1.40475648146568e-15	CD74/TYROBP/HLA-B/CYBA/TREM2/AIF1/CD84/PYCARD/HAVCR2/CLEC7A/LGALS9/LILRB4/CD36/NCKAP1L/ARRB2/HGF/LPL/TLR7/SYK/TLR2/SIRPA/MBP/TLR4/TLR1/POU2F2/LILRB2/SCIMP/PTAFR/CSK/PTPN6/KLF2/IL6R/TLR8/LILRA2/INPP5D/IRAK3/MYD88/IFIH1/ARHGEF2/IL1B/STAT3/TNFAIP3/CEBPB	43
GO:0032675	regulation of interleukin-6 production	43/1068	165/18722	1.5880308630357e-17	1.40475648146568e-15	CD74/TYROBP/HLA-B/CYBA/TREM2/AIF1/CD84/PYCARD/HAVCR2/CLEC7A/LGALS9/LILRB4/CD36/NCKAP1L/ARRB2/HGF/LPL/TLR7/SYK/TLR2/SIRPA/MBP/TLR4/TLR1/POU2F2/LILRB2/SCIMP/PTAFR/CSK/PTPN6/KLF2/IL6R/TLR8/LILRA2/INPP5D/IRAK3/MYD88/IFIH1/ARHGEF2/IL1B/STAT3/TNFAIP3/CEBPB	43
GO:0002449	lymphocyte mediated immunity	65/1068	350/18722	1.82494494017708e-17	1.58829078987024e-15	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/HLA-B/FCER1G/B2M/C1QB/TREM2/C3/C1QA/CD81/HLA-DMB/C1QC/CTSH/HLA-E/HLA-DQA2/HAVCR2/CTSC/IL18/LGALS9/GAPT/LILRB4/HLA-F/NCKAP1L/PTPRC/ARRB2/IL4I1/CORO1A/LILRB1/AHR/TNFRSF1B/HLA-DOA/WAS/SLAMF7/C2/TGFB1/TCIRG1/IRF7/RSAD2/PTPN6/BTK/HLA-DRB5/SASH3/MYO1G/BCL6/TLR8/INPP5D/MYD88/DENND1B/STAT6/ERCC1/MR1/HPRT1/IL1B/SERPING1/ARL8B/LAMP1/STX7/KIF5B	65
GO:0071216	cellular response to biotic stimulus	53/1068	246/18722	2.47319256766761e-17	2.11830906271975e-15	VIM/CD68/TREM2/TXNIP/CCL3/HAMP/LY96/TSPO/MTDH/CD14/PYCARD/LITAF/ZFP36/CD86/LY86/SPI1/HAVCR2/CLEC7A/IL18/CD36/MEF2C/LYN/RHOA/SYK/TLR2/AXL/SIRPA/LILRB1/IRF8/TNFRSF1B/CASP1/TLR4/CD180/TLR1/CARD16/TGFB1/HCK/LILRB2/SCIMP/PTAFR/IRAK1/BID/BTK/NR1H3/LILRA2/MYD88/ADAM9/IL1B/TNFAIP3/NFKBIA/CEBPB/ABCA1/TMCO1	53
GO:0071346	cellular response to interferon-gamma	36/1068	118/18722	2.72265817099234e-17	2.29554117041792e-15	HLA-DPA1/VIM/AIF1/CCL3/CCL3L3/STAT1/LGALS9/IFNGR2/GBP1/ACTR2/IFNGR1/ACTR3/CCL4/TLR2/GBP4/SIRPA/IRF8/ZYX/CASP1/TLR4/JAK1/GBP2/PARP9/WAS/SP100/CD58/HCK/JAK2/GBP5/NR1H3/PARP14/DAPK1/STX4/IRF1/CDC42/KIF5B	36
GO:0002819	regulation of adaptive immune response	45/1068	183/18722	3.19301840298486e-17	2.65069650807789e-15	HLA-DRA/HLA-DRB1/HLA-A/HLA-B/B2M/TREM2/C3/CD81/HLA-E/TNFSF13B/PYCARD/HAVCR2/CLEC7A/IL18/SLC11A1/LILRB4/HLA-F/MEF2C/NCKAP1L/PTPRC/CD4/SAMSN1/IL4I1/CD48/LILRB1/AHR/TNFRSF1B/TNFRSF14/WAS/TGFB1/IRF7/RSAD2/PTPN6/BTK/SASH3/BCL6/DENND1B/STAT6/MR1/IL1B/TNFAIP3/ADCY7/IRF1/NFKBIZ/STX7	45
GO:0032956	regulation of actin cytoskeleton organization	65/1068	357/18722	5.13893439741078e-17	4.20146818309523e-15	TMSB4X/CAPG/GPR65/BST2/PLEK/PYCARD/CCDC88A/COTL1/CSF1R/ARHGDIB/GRB2/NCKAP1L/ACTR2/ACTR3/FLNA/GMFG/RHOA/TMSB10/TWF2/CORO1A/PTGER4/RHOQ/ARPC3/RHOG/WAS/PREX1/HCK/ABI3/MYADM/NOTCH2/TRPM2/VASP/PTK2B/ARHGAP18/ARAP1/ARPC4/ARPC1B/CAPZA2/CAPZA1/CYFIP1/RAC1/RGCC/LRP1/BST1/IQGAP1/TGFBR1/PAK2/ROCK1/GSN/PAK1/FLII/RHOB/ARPC5/HCLS1/BRK1/ARF6/AKAP13/CDC42/TAOK1/DBNL/ARHGDIA/PIK3R1/CAPZB/PFN1/S100A10	65
GO:0009615	response to virus	66/1068	367/18722	5.62053833535075e-17	4.48621198783112e-15	NPC2/IFI27/CXCR4/BST2/ISG15/SAMHD1/PYCARD/IFI16/STAT1/IFI44L/MX1/IFITM3/LGALS9/IFIT3/IFNGR2/HIF1A/FGL2/PTPRC/GBP1/IFIT2/IFNGR1/PLSCR1/CCL4/RNASE6/TLR7/TRIM22/IFI44/TLR2/OAS1/ITGAX/IFIT1/OAS2/LILRB1/MX2/PARP9/UNC93B1/POU2F2/STAT2/DDIT4/IRF7/RSAD2/DTX3L/SLFN11/OAS3/TLR8/APOBEC3C/IRAK3/FGR/APOBEC3A/MYD88/BNIP3L/IFIH1/IFNAR1/TNFAIP3/EIF2AK2/RNF135/HTRA1/ADAR/IRF1/IVNS1ABP/DNAJC3/CFL1/IRF2/BAX/HNRNPUL1/PCBP2	66
GO:0050727	regulation of inflammatory response	68/1068	386/18722	5.65349175634759e-17	4.48621198783112e-15	APOE/HLA-DRB1/TMSB4X/GPX1/TREM2/C3/CD81/ACP5/CCL3/GRN/HAMP/NUPR1/HLA-E/ALOX5AP/PYCARD/ZFP36/CTSC/IL18/PLA2G7/PTPRC/NEAT1/LYN/RB1/HGF/LPL/TLR7/METRNL/SYK/TLR2/GPSM3/SIRPA/PTGER4/TNFRSF1B/ALOX5/ZYX/CASP1/TLR4/KLF4/PIK3AP1/HCK/IFI35/NCF1/BTK/JAK2/ADAM8/AOAH/NR1H3/RHBDF2/BCL6/TNFAIP8L2/LRRK2/FGR/MYD88/GPX4/LACC1/MGST2/SOCS3/IL1B/TNFAIP3/NINJ1/ABHD12/NFKBIA/BST1/CEBPB/TNFRSF1A/NFKBIZ/CEBPA/XIAP	68
GO:0002699	positive regulation of immune effector process	51/1068	235/18722	7.22527968655337e-17	5.60234676954343e-15	HLA-DRA/HLA-DRB1/CD74/TYROBP/HLA-A/HLA-B/LAPTM5/B2M/TREM2/C3/CD81/HLA-DMB/HLA-E/ITGB2/CD84/CD86/HMOX1/SPI1/CLEC7A/IL18/LGALS9/CD36/HLA-F/PTPRC/LYN/SYK/CD300A/LILRB1/TNFRSF14/RAP1A/TLR4/TGFB1/SCIMP/PTAFR/RSAD2/ITGAM/BTK/SASH3/ADGRE2/FGR/DENND1B/STAT6/LACC1/MR1/PTPRJ/STXBP2/IL1B/STX4/NFKBIZ/LAMP1/STX7	51
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	20/1068	34/18722	7.26768483817717e-17	5.60234676954343e-15	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/CTSD/HLA-DQB1/HLA-DQA1/HLA-DMA/FCER1G/B2M/TREM2/HLA-DMB/CTSS/HLA-DQA2/LGMN/PYCARD/IFI30/HLA-DOA/HLA-DRB5	20
GO:0006909	phagocytosis	59/1068	308/18722	1.30399035256085e-16	9.91032667946244e-15	TYROBP/MSR1/FCER1G/CYBA/TREM2/C3/AIF1/ITGB2/FCGR1A/CD14/PYCARD/NCF2/CLEC7A/SLC11A1/CD36/NCKAP1L/PTPRC/LYN/CD302/PECAM1/PLSCR1/SYK/MARCO/CORO1C/CD300A/TLR2/AXL/SIRPA/CORO1A/DOCK2/IRF8/RAP1A/TLR4/RHOG/C2/HCK/CSK/NCF4/ITGAM/CAMK1D/CD300LF/NR1H3/MYO1G/ITGAL/FGR/MYD88/PTPRJ/IL1B/RAC1/C1orf43/LRP1/ABCA1/ARL8B/GSN/PAK1/ATG3/CDC42/APPL1/RAB7A	59
GO:0045637	regulation of myeloid cell differentiation	47/1068	210/18722	3.37703106312448e-16	2.53089716897496e-14	HLA-DRB1/CD74/TYROBP/B2M/TREM2/MAFB/CCL3/C1QC/ISG15/FOS/STAT1/ZFP36/SPI1/ID2/EVI2B/JUN/LILRB4/HIF1A/MEF2C/ZFP36L1/NCKAP1L/LYN/RB1/CD4/CIB1/HSPA1A/LILRB1/TLR4/CCR1/TGFB1/LILRB3/IRF7/RUNX1/NOTCH2/GPR137B/RASSF2/MITF/INPP5D/PTK2B/STAT3/ATP6AP1/NFKBIA/CEBPB/SMAP1/HCLS1/KLF10/PIK3R1	47
GO:1902107	positive regulation of leukocyte differentiation	40/1068	157/18722	4.99308605970132e-16	3.64090437542545e-14	HLA-DRA/HLA-DRB1/CD74/TYROBP/TREM2/FOS/CD86/ID2/IL18/CD83/EVI2B/LGALS9/JUN/LILRB4/ZFP36L1/NCKAP1L/PTPRC/RB1/CD4/RHOA/SYK/IL4I1/AXL/ZMIZ1/CCR1/TGFB1/TGFBR2/LILRB2/RUNX1/BTK/NOTCH2/ADAM8/SASH3/BCL6/INPP5D/ATP6AP1/NFKBIZ/HCLS1/PPP2R3C/KLF10	40
GO:1903708	positive regulation of hemopoiesis	40/1068	157/18722	4.99308605970132e-16	3.64090437542545e-14	HLA-DRA/HLA-DRB1/CD74/TYROBP/TREM2/FOS/CD86/ID2/IL18/CD83/EVI2B/LGALS9/JUN/LILRB4/ZFP36L1/NCKAP1L/PTPRC/RB1/CD4/RHOA/SYK/IL4I1/AXL/ZMIZ1/CCR1/TGFB1/TGFBR2/LILRB2/RUNX1/BTK/NOTCH2/ADAM8/SASH3/BCL6/INPP5D/ATP6AP1/NFKBIZ/HCLS1/PPP2R3C/KLF10	40
GO:0002253	activation of immune response	65/1068	375/18722	6.4188309174479e-16	4.61813488407318e-14	HLA-DRB1/HLA-DPB1/HLA-DQB1/TYROBP/HLA-A/FCER1G/LAPTM5/C1QB/TREM2/C3/C1QA/CD81/C1QC/FPR3/CFD/PYCARD/IFI16/C5AR1/LGALS3/CLEC7A/A2M/C3AR1/LILRB4/MEF2C/NCKAP1L/PTPRC/GBP1/LYN/MNDA/PLSCR1/LCP2/SYK/CMTM3/LAT2/CD300A/FPR1/RAP1A/TLR4/PRNP/C2/THEMIS2/HCK/CSK/PTPN6/BTK/LPXN/VSIG4/KLHL6/MYO1G/LILRA2/INPP5D/FGR/DENND1B/RAB29/PTPRJ/IL1B/SERPING1/RGCC/DUSP3/PAK2/NFKBIZ/PAK1/BAX/WNK1/APPL1	65
GO:0032970	regulation of actin filament-based process	67/1068	396/18722	7.92371206130183e-16	5.6258355635243e-14	TMSB4X/CAPG/GPR65/BST2/PLEK/PYCARD/CCDC88A/COTL1/CSF1R/ARHGDIB/GRB2/NCKAP1L/ACTR2/ACTR3/FLNA/GMFG/RHOA/TMSB10/TWF2/CORO1A/PTGER4/RHOQ/ARPC3/RHOG/WAS/PREX1/HCK/ABI3/MYADM/NOTCH2/TRPM2/VASP/PTK2B/ARHGAP18/ARAP1/ARPC4/ARPC1B/CAPZA2/CAPZA1/CYFIP1/RAC1/RGCC/LRP1/ABRACL/BST1/IQGAP1/TGFBR1/PAK2/ROCK1/GSN/PAK1/FLII/RHOB/ARPC5/HCLS1/BRK1/ARF6/AKAP13/CDC42/TAOK1/DBNL/ARHGDIA/PIK3R1/ATP1A1/CAPZB/PFN1/S100A10	67
GO:0007162	negative regulation of cell adhesion	57/1068	303/18722	1.00549803517123e-15	7.0463212958233e-14	HLA-DRB1/CD74/GPNMB/LGALS1/LAPTM5/CD9/FXYD5/TGFBI/DUSP1/CD86/SPI1/LGALS3/HAVCR2/ARHGDIB/LGALS9/LILRB4/FGL2/NCKAP1L/PTPRC/GBP1/PLXNC1/RHOA/CORO1C/IL4I1/CD300A/LILRB1/MBP/TNFRSF14/KLF4/PRNP/VEGFA/PLXND1/TGFB1/LILRB2/PAG1/RUNX1/PTPN6/MYADM/JAK2/LPXN/VSIG4/SH2B3/BCL6/TNFAIP8L2/SPN/RGCC/LRP1/CEBPB/PRKAR1A/DUSP3/IRF1/ADAM10/RCC2/WNK1/ARHGDIA/PIK3R1/SOCS6	57
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	18/1068	30/18722	1.60428581747408e-15	1.10983670142181e-13	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/CTSD/HLA-DQB1/HLA-DQA1/HLA-DMA/FCER1G/B2M/HLA-DMB/CTSS/HLA-DQA2/LGMN/IFI30/HLA-DOA/HLA-DRB5	18
GO:0032602	chemokine production	31/1068	99/18722	1.95946334042789e-15	1.33838787151252e-13	CD74/TREM2/AIF1/CD84/PYCARD/HMOX1/HAVCR2/CLEC7A/CSF1R/IL18/LGALS9/LILRB4/HIF1A/LPL/TLR7/SYK/TLR2/OAS1/SIRPA/MBP/TLR4/KLF4/TREM1/OAS3/IL6R/MYD88/IL1B/EIF2AK2/LRP1/ADAM17/EGR1	31
GO:0016032	viral process	68/1068	415/18722	2.52118003922132e-15	1.70053593645478e-13	APOE/HLA-DRB1/CD74/LGALS1/CTSB/CD81/IFI27/CCL3/CXCR4/BST2/ISG15/IFI16/STAT1/ZFP36/CD86/MX1/IFITM3/MGAT4A/LGALS9/JUN/CD4/PLSCR1/USF2/CCL4/TRIM22/OAS1/CLEC5A/AXL/HSPA1A/IFIT1/OAS2/MGAT1/TNFRSF14/PABPC1/ANPEP/PARP9/CIITA/MDFIC/IRF7/SIGLEC1/RSAD2/SELPLG/OAS3/TRIM14/APOBEC3C/ITGA5/APOBEC3A/SCARB2/IFIH1/TRIM38/RAB29/EIF2AK2/KPNA3/SPCS3/IGF2R/ADAR/DDX5/ARL8B/GSN/FAM111A/CANX/CFL1/LAMP1/CDC42/CHMP3/RAB7A/PCBP2/CHMP1B	68
GO:0071219	cellular response to molecule of bacterial origin	47/1068	221/18722	2.73691624034558e-15	1.82325926332157e-13	VIM/CD68/TREM2/CCL3/HAMP/LY96/TSPO/MTDH/CD14/PYCARD/LITAF/ZFP36/CD86/LY86/SPI1/HAVCR2/IL18/CD36/MEF2C/LYN/RHOA/TLR2/AXL/SIRPA/LILRB1/IRF8/TNFRSF1B/CASP1/TLR4/CD180/TLR1/CARD16/TGFB1/HCK/LILRB2/SCIMP/PTAFR/IRAK1/NR1H3/LILRA2/MYD88/ADAM9/IL1B/TNFAIP3/NFKBIA/CEBPB/ABCA1	47
GO:0031348	negative regulation of defense response	51/1068	258/18722	4.16714715487706e-15	2.74218610338008e-13	APOE/HLA-DRB1/HLA-A/HLA-B/GPX1/TREM2/ACP5/GRN/HAMP/HLA-E/ISG15/SAMHD1/IFI16/ZFP36/HAVCR2/A2M/LGALS9/HLA-F/FGL2/PTPRC/ARRB2/LYN/RB1/HGF/METRNL/SYK/OAS1/SIRPA/LILRB1/PTGER4/TNFRSF1B/ALOX5/KLF4/STAT2/HCK/AOAH/VSIG4/NR1H3/OAS3/RHBDF2/TNFAIP8L2/IRAK3/FGR/PARP14/SOCS3/SERPING1/TNFAIP3/HTRA1/ADAR/TNFRSF1A/PCBP2	51
GO:0032722	positive regulation of chemokine production	26/1068	71/18722	5.06909829357551e-15	3.2810631911831e-13	CD74/AIF1/CD84/PYCARD/HMOX1/HAVCR2/CLEC7A/CSF1R/IL18/LGALS9/HIF1A/LPL/TLR7/SYK/TLR2/OAS1/MBP/TLR4/OAS3/IL6R/MYD88/IL1B/EIF2AK2/LRP1/ADAM17/EGR1	26
GO:0007015	actin filament organization	70/1068	441/18722	5.10765952667494e-15	3.2810631911831e-13	TMSB4X/MARCKS/CAPG/AIF1/GPR65/PLEK/PYCARD/CCDC88A/COTL1/LCP1/GRB2/PHACTR1/NCKAP1L/ACTR2/ACTR3/FLNA/TPM3/WIPF1/GMFG/RHOA/TMSB10/CORO1C/TWF2/CORO1A/PTGER4/ARPC3/ZYX/RHOG/WAS/PREX1/HCK/MYO5A/MYO1F/MYADM/JAK2/MYO1G/VASP/ARHGEF2/PTK2B/ARHGAP18/ARAP1/ARPC4/ABI1/ARPC1B/CAPZA2/CAPZA1/CYFIP1/RAC1/SH3KBP1/SHTN1/RGCC/TGFBR1/PAK2/ROCK1/GSN/PAK1/FLII/RHOB/ARPC5/HCLS1/CFL1/BRK1/ARF6/CDC42/DBNL/PIK3R1/PLEC/CAPZB/PFN1/S100A10	70
GO:0031349	positive regulation of defense response	53/1068	278/18722	5.83106832562736e-15	3.70169937471591e-13	TYROBP/CYBA/TREM2/C3/CD81/CCL3/GRN/NUPR1/HLA-E/ALOX5AP/PYCARD/IFI16/SPI1/HAVCR2/CTSC/CLEC7A/IL18/HLA-F/MEF2C/PLA2G7/NEAT1/LYN/MNDA/LPL/PLSCR1/TLR7/SYK/TLR2/GPSM3/PTGER4/TLR4/PARP9/HCK/IRF7/IFI35/BTK/JAK2/ADAM8/GBP5/TLR8/LILRA2/LRRK2/MGST2/IL1B/NINJ1/NFKBIA/CEBPB/TNFRSF1A/PAK2/NFKBIZ/CEBPA/PAK1/LAMP1	53
GO:0042113	B cell activation	59/1068	334/18722	6.08096701345733e-15	3.81545325635067e-13	CD74/LGALS1/TYROBP/LAPTM5/CD81/BST2/ZFP36L2/TNFSF13B/CD86/SPI1/KLF6/ID2/GAPT/MEF2C/ZFP36L1/NCKAP1L/PTPRC/LYN/SKAP2/GPR183/SAMSN1/MNDA/DOCK10/SYK/LAT2/IL4I1/CD300A/IRF8/AHR/TLR4/CD180/TGFB1/THEMIS2/TCIRG1/LYL1/PTPN6/BTK/NOTCH2/CMTM7/SASH3/ITGA4/BCL6/LFNG/INPP5D/PTK2B/CDKN1A/STAT6/ERCC1/PTPRJ/SH3KBP1/TNFAIP3/BST1/ATM/ADAM17/PPP2R3C/FNIP1/IRF2BP2/BAX/PIK3R1	59
GO:0071222	cellular response to lipopolysaccharide	45/1068	209/18722	6.6495654278485e-15	4.12425920099661e-13	VIM/CD68/CCL3/HAMP/LY96/TSPO/MTDH/CD14/PYCARD/LITAF/ZFP36/CD86/LY86/SPI1/HAVCR2/IL18/CD36/MEF2C/LYN/RHOA/TLR2/AXL/SIRPA/LILRB1/IRF8/TNFRSF1B/CASP1/TLR4/CD180/CARD16/TGFB1/HCK/LILRB2/SCIMP/PTAFR/IRAK1/NR1H3/LILRA2/MYD88/ADAM9/IL1B/TNFAIP3/NFKBIA/CEBPB/ABCA1	45
GO:0032642	regulation of chemokine production	30/1068	98/18722	1.10604795565757e-14	6.78208496446392e-13	CD74/TREM2/AIF1/CD84/PYCARD/HMOX1/HAVCR2/CLEC7A/CSF1R/IL18/LGALS9/LILRB4/HIF1A/LPL/TLR7/SYK/TLR2/OAS1/SIRPA/MBP/TLR4/KLF4/OAS3/IL6R/MYD88/IL1B/EIF2AK2/LRP1/ADAM17/EGR1	30
GO:0051607	defense response to virus	51/1068	265/18722	1.28881462094043e-14	7.72715966066061e-13	IFI27/BST2/ISG15/SAMHD1/PYCARD/IFI16/STAT1/IFI44L/MX1/IFITM3/IFIT3/IFNGR2/FGL2/PTPRC/GBP1/IFIT2/PLSCR1/RNASE6/TLR7/TRIM22/TLR2/OAS1/ITGAX/IFIT1/OAS2/LILRB1/MX2/PARP9/UNC93B1/STAT2/DDIT4/IRF7/RSAD2/DTX3L/SLFN11/OAS3/TLR8/APOBEC3C/APOBEC3A/MYD88/BNIP3L/IFIH1/TNFAIP3/EIF2AK2/RNF135/HTRA1/ADAR/IRF1/DNAJC3/IRF2/PCBP2	51
GO:0140546	defense response to symbiont	51/1068	265/18722	1.28881462094043e-14	7.72715966066061e-13	IFI27/BST2/ISG15/SAMHD1/PYCARD/IFI16/STAT1/IFI44L/MX1/IFITM3/IFIT3/IFNGR2/FGL2/PTPRC/GBP1/IFIT2/PLSCR1/RNASE6/TLR7/TRIM22/TLR2/OAS1/ITGAX/IFIT1/OAS2/LILRB1/MX2/PARP9/UNC93B1/STAT2/DDIT4/IRF7/RSAD2/DTX3L/SLFN11/OAS3/TLR8/APOBEC3C/APOBEC3A/MYD88/BNIP3L/IFIH1/TNFAIP3/EIF2AK2/RNF135/HTRA1/ADAR/IRF1/DNAJC3/IRF2/PCBP2	51
GO:0042116	macrophage activation	31/1068	106/18722	1.6347752984102e-14	9.69367858266095e-13	CD74/TYROBP/TREM2/AIF1/C1QA/CCL3/GRN/HAMP/ITGB2/CD84/C5AR1/HAVCR2/CTSC/SLC11A1/IFNGR2/PTPRC/IFNGR1/SYK/TLR2/TLR4/TLR1/IFI35/ITGAM/JAK2/GPR137B/VSIG4/NR1H3/NAMPT/LRRK2/CEBPA/PJA2	31
GO:0002761	regulation of myeloid leukocyte differentiation	33/1068	120/18722	1.68315490396348e-14	9.87206941498581e-13	HLA-DRB1/CD74/TYROBP/TREM2/MAFB/CCL3/C1QC/FOS/ID2/EVI2B/JUN/LILRB4/ZFP36L1/LYN/RB1/CD4/LILRB1/TLR4/CCR1/TGFB1/LILRB3/IRF7/RUNX1/NOTCH2/GPR137B/RASSF2/MITF/INPP5D/ATP6AP1/CEBPB/HCLS1/KLF10/PIK3R1	33
GO:0002685	regulation of leukocyte migration	44/1068	210/18722	3.73629287286099e-14	2.167853370103e-12	CD74/TREM2/CD9/AIF1/CD81/CCL3/LGMN/DUSP1/PYCARD/C5AR1/HMOX1/SPI1/LGALS3/CSF1R/MSN/C3AR1/LGALS9/PLA2G7/NCKAP1L/LYN/CCL4/RHOA/CD300A/GPSM3/PTGER4/TNFRSF14/RHOG/VEGFA/CCR1/PTAFR/CAMK1D/ADAM8/RIN3/IL6R/ITGA4/SPN/MYD88/PTK2B/RAC1/BST1/VEGFB/ADAM17/ADAM10/WNK1	44
GO:0002285	lymphocyte activation involved in immune response	42/1068	194/18722	4.36399265829547e-14	2.50511748767684e-12	HLA-DRA/HLA-DRB1/CD74/LGALS1/FCER1G/CD81/HLA-DMB/APBB1IP/CD86/SPI1/LGALS3/LCP1/HAVCR2/IL18/SLC11A1/LGALS9/GAPT/HLA-F/FGL2/NCKAP1L/PTPRC/GPR183/DOCK10/CORO1A/LILRB1/IRF8/PTGER4/TLR4/CD180/TGFB1/NOTCH2/IL6R/BCL6/LFNG/SPN/ITGAL/PTK2B/STAT6/ERCC1/STAT3/NFKBIZ/LAMP1	42
GO:0031663	lipopolysaccharide-mediated signaling pathway	23/1068	60/18722	6.03392129105607e-14	3.42726729331985e-12	CCL3/LY96/MTDH/CD14/LY86/SPI1/IL18/CD36/LYN/TLR2/TLR4/CD180/CARD16/TGFB1/HCK/SCIMP/PTAFR/IRAK1/LILRA2/MYD88/IL1B/TNFAIP3/NFKBIA	23
GO:1902903	regulation of supramolecular fiber organization	62/1068	382/18722	6.91239504359051e-14	3.88534204741817e-12	APOE/TMSB4X/CAPG/GPX1/TREM2/GPR65/PLEK/PYCARD/CCDC88A/COTL1/GRB2/NCKAP1L/RB1/ACTR2/ACTR3/FLNA/GMFG/RHOA/TMSB10/TWF2/CIB1/HSPA1A/CORO1A/PTGER4/ARPC3/WAS/PREX1/HCK/COLGALT1/MYADM/VASP/ARHGEF2/PTK2B/ARHGAP18/ARAP1/ARPC4/ARPC1B/CAPZA2/CAPZA1/CYFIP1/RAC1/RGCC/TGFBR1/PAK2/ROCK1/APC/GSN/PAK1/FLII/ARPC5/PFDN5/HCLS1/BRK1/ARF6/AKAP13/CDC42/TAOK1/DBNL/PIK3R1/CAPZB/PFN1/S100A10	62
GO:0002275	myeloid cell activation involved in immune response	28/1068	91/18722	7.37724572667136e-14	4.10387813825966e-12	TYROBP/FCER1G/TREM2/CCL3/GRN/ITGB2/CD84/PYCARD/HMOX1/SPI1/HAVCR2/LGALS9/LYN/SYK/LAT2/CD300A/DOCK2/PTAFR/IFI35/MILR1/ITGAM/BTK/ADGRE2/LILRA2/FGR/MYD88/STXBP2/STX4	28
GO:0006898	receptor-mediated endocytosis	47/1068	244/18722	1.37458755273981e-13	7.5686473822286e-12	APOE/APOC1/MSR1/FCER1G/B2M/C3/CD9/CD81/ITGB2/SORL1/CXCL16/CD14/PPT1/CD63/BMP2K/GRB2/LILRB4/CD36/ARRB2/M6PR/SDCBP/ASGR1/SYK/MARCO/LILRB1/VEGFA/TGFBR2/SIGLEC1/STAB1/PDLIM7/ITGAM/RIN3/ITGA4/ITSN2/SCARB2/CAP1/RAC1/LRP1/IGF2R/NUMB/SMAP1/CANX/FCHO2/PICALM/ARF6/DBNL/FLOT1	47
GO:0048872	homeostasis of number of cells	50/1068	272/18722	1.51300938095471e-13	8.24666527235516e-12	CD74/B2M/MAFB/LIPA/HAMP/ISG15/TNFSF13B/DNASE2/STAT1/ZFP36/HMOX1/SPI1/ID2/SKIL/LGALS9/GAPT/HIF1A/MEF2C/ZFP36L1/NCKAP1L/LYN/RB1/GPR183/DOCK10/AXL/HSPA1A/CORO1A/VEGFA/TCIRG1/JAK2/RASSF2/KLF2/SASH3/IKZF1/SH2B3/BCL6/TSC22D3/INPP5D/KMT2E/STAT3/TNFAIP3/ARID4A/ADAR/ADAM17/SMAP1/HCLS1/PPP2R3C/PTBP3/BAX/CAMLG	50
GO:0060326	cell chemotaxis	54/1068	310/18722	1.58152820346629e-13	8.53392618590409e-12	CD74/TMSB4X/FCER1G/AIF1/CCL3/CCL3L3/CXCR4/ITGB2/CXCL16/LGMN/DUSP1/C5AR1/SPI1/LGALS3/CSF1R/C3AR1/LGALS9/DOCK4/PLA2G7/NCKAP1L/ARRB2/CKLF/LYN/GPR183/HGF/CCL4/SYK/GPSM3/CORO1A/ALOX5/RHOG/HBEGF/VEGFA/PREX1/CCR1/TREM1/CAMK1D/CCRL2/ADAM8/TRPM2/RIN3/IL6R/ADGRE2/PTK2B/RAC1/NINJ1/BST1/VEGFB/ADAM17/NR4A1/ADAM10/WNK1/PLEC/RAB13	54
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	38/1068	168/18722	1.65027158061822e-13	8.81669846437221e-12	HLA-DRA/HLA-DRB1/HLA-A/HLA-B/B2M/TREM2/C3/CD81/HLA-E/TNFSF13B/HAVCR2/CLEC7A/IL18/SLC11A1/LILRB4/HLA-F/MEF2C/NCKAP1L/PTPRC/CD4/IL4I1/LILRB1/AHR/TNFRSF1B/WAS/TGFB1/RSAD2/PTPN6/BTK/SASH3/BCL6/DENND1B/STAT6/MR1/IL1B/TNFAIP3/NFKBIZ/STX7	38
GO:0002832	negative regulation of response to biotic stimulus	30/1068	108/18722	1.9603721401172e-13	1.03707530079141e-11	HLA-A/HLA-B/GRN/HLA-E/ISG15/SAMHD1/IFI16/HAVCR2/A2M/LGALS9/HLA-F/FGL2/ARRB2/IL4I1/OAS1/LILRB1/AHR/STAT2/CARD16/VSIG4/NR1H3/OAS3/LILRA2/IRAK3/PARP14/SERPING1/TNFAIP3/HTRA1/ADAR/PCBP2	30
GO:0050764	regulation of phagocytosis	28/1068	95/18722	2.45783205883928e-13	1.28761764946571e-11	FCER1G/CYBA/TREM2/C3/PYCARD/CLEC7A/SLC11A1/CD36/NCKAP1L/PTPRC/PLSCR1/SYK/CD300A/TLR2/SIRPA/DOCK2/RAP1A/C2/HCK/CSK/CAMK1D/CD300LF/FGR/PTPRJ/IL1B/LRP1/ATG3/APPL1	28
GO:0030595	leukocyte chemotaxis	45/1068	230/18722	2.55833521715834e-13	1.32738238767177e-11	CD74/FCER1G/AIF1/CCL3/CCL3L3/CXCR4/ITGB2/CXCL16/LGMN/DUSP1/C5AR1/SPI1/LGALS3/CSF1R/C3AR1/LGALS9/PLA2G7/NCKAP1L/CKLF/LYN/GPR183/CCL4/SYK/GPSM3/CORO1A/ALOX5/VEGFA/PREX1/CCR1/TREM1/CAMK1D/ADAM8/TRPM2/RIN3/IL6R/ADGRE2/PTK2B/RAC1/NINJ1/BST1/VEGFB/ADAM17/ADAM10/WNK1/PLEC	45
GO:0022408	negative regulation of cell-cell adhesion	41/1068	196/18722	2.95062466003901e-13	1.51634006338766e-11	HLA-DRB1/CD74/GPNMB/LAPTM5/CD9/FXYD5/CD86/SPI1/LGALS3/HAVCR2/LGALS9/LILRB4/FGL2/NCKAP1L/IL4I1/CD300A/LILRB1/MBP/TNFRSF14/KLF4/PRNP/VEGFA/TGFB1/LILRB2/PAG1/RUNX1/PTPN6/MYADM/JAK2/VSIG4/SH2B3/BCL6/TNFAIP8L2/SPN/RGCC/CEBPB/PRKAR1A/DUSP3/IRF1/WNK1/SOCS6	41
GO:0110053	regulation of actin filament organization	50/1068	277/18722	3.13089705187451e-13	1.59380381999197e-11	TMSB4X/CAPG/GPR65/PLEK/PYCARD/CCDC88A/COTL1/GRB2/NCKAP1L/ACTR2/ACTR3/FLNA/GMFG/RHOA/TMSB10/TWF2/CORO1A/PTGER4/ARPC3/WAS/PREX1/HCK/MYADM/VASP/PTK2B/ARHGAP18/ARAP1/ARPC4/ARPC1B/CAPZA2/CAPZA1/CYFIP1/RAC1/RGCC/TGFBR1/PAK2/ROCK1/GSN/PAK1/FLII/ARPC5/HCLS1/BRK1/ARF6/CDC42/DBNL/PIK3R1/CAPZB/PFN1/S100A10	50
GO:0002698	negative regulation of immune effector process	30/1068	110/18722	3.33062602324213e-13	1.67963159078641e-11	HLA-A/HLA-B/GRN/HLA-E/BST2/CD84/HMOX1/SPI1/LGALS3/HAVCR2/A2M/LGALS9/LILRB4/HLA-F/FGL2/NCKAP1L/PTPRC/ARRB2/IL4I1/TMBIM6/CD300A/LILRB1/AHR/TGFB1/PTPN6/VSIG4/BCL6/IRAK3/SERPING1/APPL1	30
GO:0043254	regulation of protein-containing complex assembly	65/1068	427/18722	3.6243218043581e-13	1.81081856077003e-11	APOE/TMSB4X/CAPG/TREM2/ISG15/PLEK/SORL1/PYCARD/COTL1/LGALS3/LCP1/CLEC7A/MSN/GRB2/CD36/NCKAP1L/RB1/ACTR2/ACTR3/GMFG/RHOA/TMSB10/SYK/TWF2/HSPA1A/CORO1A/PTGER4/ARPC3/EIF4EBP1/TLR4/VEGFA/WAS/PREX1/TGFB1/HCK/BID/MYADM/GBP5/MYD88/VASP/PTK2B/FNIP2/ARHGAP18/ARPC4/ARPC1B/CAPZA2/CAPZA1/CYFIP1/RAC1/EIF2AK2/ATM/ABCA1/GSN/PAK1/FLII/ARPC5/HCLS1/BRK1/ARF6/FNIP1/CDC42/BAX/DBNL/CAPZB/PFN1	65
GO:0042098	T cell proliferation	41/1068	199/18722	5.01434192041594e-13	2.48232926629031e-11	HLA-DRB1/HLA-DPA1/HLA-DPB1/GPNMB/HLA-A/AIF1/CD81/HLA-DMB/HLA-E/TNFSF13B/PYCARD/CD86/LGALS3/HAVCR2/IL18/MSN/SLC11A1/LGALS9/LILRB4/NCKAP1L/PTPRC/SYK/IL4I1/CORO1A/DOCK2/LILRB1/TNFRSF1B/TNFRSF14/PRNP/TGFBR2/LILRB2/PTPN6/VSIG4/SASH3/SPN/IL1B/PSMB10/CEBPB/PRKAR1A/IRF1/BAX	41
GO:0002367	cytokine production involved in immune response	28/1068	98/18722	5.78842386476407e-13	2.83948501584245e-11	CD74/HLA-A/LAPTM5/B2M/CD81/HLA-E/BST2/HMOX1/CLEC7A/IL18/LILRB4/CD36/HLA-F/LILRB1/TNFRSF1B/TNFRSF14/TLR4/TGFB1/TREM1/SCIMP/RSAD2/BTK/SASH3/BCL6/IRAK3/DENND1B/LACC1/IL1B	28
GO:0032755	positive regulation of interleukin-6 production	27/1068	93/18722	9.81838705104414e-13	4.77297446193101e-11	CD74/TYROBP/CYBA/AIF1/PYCARD/CLEC7A/LGALS9/CD36/LPL/TLR7/SYK/TLR2/MBP/TLR4/TLR1/POU2F2/LILRB2/SCIMP/PTAFR/IL6R/TLR8/LILRA2/MYD88/IFIH1/ARHGEF2/IL1B/STAT3	27
GO:0030217	T cell differentiation	47/1068	257/18722	9.93378769875309e-13	4.7859570020064e-11	HLA-DRA/HLA-DRB1/CD74/FCER1G/B2M/MAFB/ZFP36L2/CD86/SPI1/IL18/CD83/LGALS9/LILRB4/ZFP36L1/FGL2/NCKAP1L/PTPRC/GPR183/CD4/RHOA/SYK/IL4I1/DOCK2/PTGER4/HLA-DOA/ZMIZ1/PREX1/TGFBR2/TCIRG1/LILRB2/RSAD2/PRDM1/RUNX1/ADAM8/SASH3/IL6R/BCL6/LFNG/SPN/STAT6/MR1/IL1B/STAT3/IRF1/ADAM17/NFKBIZ/EGR1	47
GO:0002768	immune response-regulating cell surface receptor signaling pathway	53/1068	315/18722	1.10216774141343e-12	5.26309480766978e-11	HLA-DRB1/HLA-DPB1/HLA-DQB1/TYROBP/HLA-A/FCER1G/LAPTM5/CD81/FPR3/C5AR1/LGALS3/CLEC7A/C3AR1/LILRB4/MEF2C/NCKAP1L/PTPRC/GBP1/LYN/MNDA/PLSCR1/LCP2/SYK/CMTM3/LAT2/CD300A/FPR1/FCGR1B/LILRB1/RAP1A/PRNP/THEMIS2/HCK/LILRB2/CSK/PTPN6/BTK/LPXN/KLHL6/MYO1G/LILRA2/INPP5D/FGR/DENND1B/RAB29/PTPRJ/DUSP3/PAK2/NFKBIZ/PAK1/BAX/WNK1/APPL1	53
GO:0002396	MHC protein complex assembly	13/1068	19/18722	1.24232614132304e-12	5.88034373559574e-11	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQB1/HLA-DQA1/HLA-DMA/B2M/HLA-DMB/HLA-DQA2/HLA-DOA/TAPBP/HLA-DRB5	13
GO:0030316	osteoclast differentiation	27/1068	94/18722	1.30369268604544e-12	6.11715281208798e-11	TYROBP/TREM2/CD81/MAFB/CCL3/SNX10/FOS/CSF1R/LILRB4/JUNB/GPR183/LILRB1/OSCAR/TLR4/CCR1/LILRB3/TCIRG1/NOTCH2/GPR137B/RASSF2/MITF/INPP5D/ATP6AP1/CEBPB/OSTM1/KLF10/PIK3R1	27
GO:0019058	viral life cycle	53/1068	317/18722	1.42386012948182e-12	6.62340453334818e-11	APOE/HLA-DRB1/CD74/LGALS1/CTSB/CD81/IFI27/CXCR4/BST2/ISG15/IFI16/CD86/MX1/IFITM3/LGALS9/CD4/PLSCR1/TRIM22/OAS1/CLEC5A/AXL/HSPA1A/IFIT1/OAS2/TNFRSF14/PABPC1/ANPEP/CIITA/SIGLEC1/RSAD2/SELPLG/OAS3/TRIM14/APOBEC3C/ITGA5/APOBEC3A/SCARB2/IFIH1/TRIM38/RAB29/EIF2AK2/KPNA3/ADAR/DDX5/ARL8B/GSN/FAM111A/LAMP1/CDC42/CHMP3/RAB7A/PCBP2/CHMP1B	53
GO:0002399	MHC class II protein complex assembly	12/1068	16/18722	1.64584068292124e-12	7.52623417376525e-11	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQB1/HLA-DQA1/HLA-DMA/B2M/HLA-DMB/HLA-DQA2/HLA-DOA/HLA-DRB5	12
GO:0002503	peptide antigen assembly with MHC class II protein complex	12/1068	16/18722	1.64584068292124e-12	7.52623417376525e-11	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQB1/HLA-DQA1/HLA-DMA/B2M/HLA-DMB/HLA-DQA2/HLA-DOA/HLA-DRB5	12
GO:0001909	leukocyte mediated cytotoxicity	31/1068	124/18722	1.70608210185721e-12	7.7361504383374e-11	HLA-DRA/HLA-DRB1/TYROBP/HLA-A/HLA-B/B2M/CTSH/HLA-E/SPI1/HAVCR2/CTSC/IL18/LGALS9/HLA-F/NCKAP1L/PTPRC/ARRB2/CORO1A/LILRB1/SLAMF7/TREM1/ITGAM/PTPN6/MYD88/MR1/HPRT1/STXBP2/ARL8B/LAMP1/STX7/KIF5B	31
GO:0050792	regulation of viral process	36/1068	164/18722	1.85466021514445e-12	8.33978876743286e-11	HLA-DRB1/CD74/LGALS1/CXCR4/BST2/ISG15/IFI16/STAT1/ZFP36/MX1/IFITM3/LGALS9/CD4/PLSCR1/TRIM22/OAS1/AXL/IFIT1/OAS2/PABPC1/CIITA/MDFIC/RSAD2/OAS3/TRIM14/APOBEC3C/APOBEC3A/IFIH1/TRIM38/EIF2AK2/ADAR/DDX5/GSN/FAM111A/CHMP3/RAB7A	36
GO:0046631	alpha-beta T cell activation	35/1068	156/18722	1.92561574062574e-12	8.58729135241030e-11	HLA-DRA/HLA-DRB1/HLA-A/CD81/HLA-E/CD86/IL18/CD83/LGALS9/LILRB4/NCKAP1L/PTPRC/GPR183/RHOA/SYK/CD300A/DOCK2/LILRB1/PTGER4/TNFRSF14/TGFBR2/TCIRG1/RSAD2/PRDM1/RUNX1/SASH3/IL6R/BCL6/CLEC4A/SPN/STAT6/STAT3/IRF1/HSPH1/NFKBIZ	35
GO:0002429	immune response-activating cell surface receptor signaling pathway	50/1068	291/18722	2.16390144620732e-12	9.49301805181681e-11	HLA-DRB1/HLA-DPB1/HLA-DQB1/TYROBP/HLA-A/FCER1G/LAPTM5/CD81/FPR3/C5AR1/LGALS3/CLEC7A/C3AR1/LILRB4/MEF2C/NCKAP1L/PTPRC/GBP1/LYN/MNDA/PLSCR1/LCP2/SYK/CMTM3/LAT2/CD300A/FPR1/RAP1A/PRNP/THEMIS2/HCK/CSK/PTPN6/BTK/LPXN/KLHL6/MYO1G/LILRA2/INPP5D/FGR/DENND1B/RAB29/PTPRJ/DUSP3/PAK2/NFKBIZ/PAK1/BAX/WNK1/APPL1	50
GO:0002757	immune response-activating signal transduction	50/1068	291/18722	2.16390144620732e-12	9.49301805181681e-11	HLA-DRB1/HLA-DPB1/HLA-DQB1/TYROBP/HLA-A/FCER1G/LAPTM5/CD81/FPR3/C5AR1/LGALS3/CLEC7A/C3AR1/LILRB4/MEF2C/NCKAP1L/PTPRC/GBP1/LYN/MNDA/PLSCR1/LCP2/SYK/CMTM3/LAT2/CD300A/FPR1/RAP1A/PRNP/THEMIS2/HCK/CSK/PTPN6/BTK/LPXN/KLHL6/MYO1G/LILRA2/INPP5D/FGR/DENND1B/RAB29/PTPRJ/DUSP3/PAK2/NFKBIZ/PAK1/BAX/WNK1/APPL1	50
GO:0002718	regulation of cytokine production involved in immune response	27/1068	96/18722	2.26975678059947e-12	9.87710289364093e-11	CD74/HLA-A/LAPTM5/B2M/CD81/HLA-E/BST2/HMOX1/CLEC7A/IL18/LILRB4/CD36/HLA-F/LILRB1/TNFRSF1B/TNFRSF14/TLR4/TGFB1/SCIMP/RSAD2/BTK/SASH3/BCL6/IRAK3/DENND1B/LACC1/IL1B	27
GO:0008154	actin polymerization or depolymerization	42/1068	217/18722	2.33558850530977e-12	1.00822684597212e-10	TMSB4X/CAPG/AIF1/PLEK/PYCARD/COTL1/GRB2/NCKAP1L/ACTR2/ACTR3/WIPF1/GMFG/RHOA/TMSB10/TWF2/CORO1A/ARPC3/WAS/PREX1/HCK/MYADM/JAK2/VASP/PTK2B/ARHGAP18/ARPC4/ABI1/ARPC1B/CAPZA2/CAPZA1/CYFIP1/RAC1/GSN/FLII/ARPC5/HCLS1/CFL1/BRK1/ARF6/DBNL/CAPZB/PFN1	42
GO:0030183	B cell differentiation	33/1068	141/18722	2.38347370409867e-12	1.02073207200924e-10	LGALS1/ZFP36L2/TNFSF13B/SPI1/KLF6/ID2/ZFP36L1/NCKAP1L/PTPRC/GPR183/DOCK10/SYK/IL4I1/IRF8/TCIRG1/LYL1/PTPN6/BTK/NOTCH2/CMTM7/ITGA4/BCL6/LFNG/INPP5D/PTK2B/PTPRJ/ATM/ADAM17/PPP2R3C/FNIP1/IRF2BP2/BAX/PIK3R1	33
GO:0002687	positive regulation of leukocyte migration	32/1068	135/18722	3.54960316218223e-12	1.50816209945948e-10	CD74/TREM2/AIF1/CCL3/LGMN/PYCARD/C5AR1/SPI1/LGALS3/CSF1R/C3AR1/LGALS9/PLA2G7/NCKAP1L/CCL4/RHOA/GPSM3/TNFRSF14/VEGFA/CCR1/PTAFR/CAMK1D/ADAM8/IL6R/ITGA4/SPN/PTK2B/RAC1/VEGFB/ADAM17/ADAM10/WNK1	32
GO:0045824	negative regulation of innate immune response	23/1068	71/18722	3.73768343626223e-12	1.5756671735993e-10	HLA-A/HLA-B/GRN/HLA-E/ISG15/SAMHD1/IFI16/HAVCR2/A2M/LGALS9/HLA-F/ARRB2/OAS1/LILRB1/STAT2/VSIG4/NR1H3/OAS3/IRAK3/PARP14/SERPING1/TNFAIP3/ADAR	23
GO:0071674	mononuclear cell migration	39/1068	196/18722	5.82215105228272e-12	2.43537419210213e-10	AIF1/CCL3/CCL3L3/CXCR4/CXCL16/LGMN/DUSP1/PYCARD/C5AR1/SPI1/LGALS3/CSF1R/MSN/C3AR1/LGALS9/PLA2G7/CKLF/LYN/GPR183/PECAM1/CCL4/RHOA/SIRPA/ALOX5/TNFRSF14/CCR1/ADAM8/TRPM2/IL6R/ITGA4/MYO1G/SPN/ITGAL/PTK2B/ADAM17/ADAM10/CDC42/WNK1/PLEC	39
GO:0042129	regulation of T cell proliferation	36/1068	171/18722	6.81741035839646e-12	2.82974971491595e-10	HLA-DRB1/HLA-DPA1/HLA-DPB1/GPNMB/HLA-A/AIF1/CD81/HLA-DMB/HLA-E/TNFSF13B/PYCARD/CD86/LGALS3/HAVCR2/IL18/LGALS9/LILRB4/NCKAP1L/PTPRC/SYK/IL4I1/CORO1A/LILRB1/TNFRSF1B/TNFRSF14/PRNP/TGFBR2/LILRB2/PTPN6/VSIG4/SASH3/SPN/IL1B/CEBPB/PRKAR1A/IRF1	36
GO:0043299	leukocyte degranulation	23/1068	73/18722	7.18489484414224e-12	2.95951851748027e-10	CCL3/ITGB2/CD84/HMOX1/SPI1/LGALS9/HLA-F/NCKAP1L/LYN/SYK/LAT2/CD300A/CORO1A/HCK/PTAFR/MILR1/ITGAM/BTK/ADGRE2/FGR/STXBP2/STX4/LAMP1	23
GO:0030041	actin filament polymerization	38/1068	190/18722	9.24807041789938e-12	3.78049908901402e-10	TMSB4X/CAPG/AIF1/PYCARD/COTL1/GRB2/NCKAP1L/ACTR2/ACTR3/GMFG/RHOA/TMSB10/TWF2/CORO1A/ARPC3/WAS/PREX1/HCK/MYADM/JAK2/VASP/PTK2B/ARHGAP18/ARPC4/ARPC1B/CAPZA2/CAPZA1/CYFIP1/RAC1/GSN/FLII/ARPC5/HCLS1/BRK1/ARF6/DBNL/CAPZB/PFN1	38
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	46/1068	264/18722	1.0058722336561e-11	4.08096734797619e-10	CD74/TREM2/CD81/ITGB2/FCGR1A/CD44/CLEC7A/CSF1R/IL18/LILRB4/CD36/RAP2B/PTPRC/ARRB2/LYN/HGF/PECAM1/CD4/SAMSN1/SYK/CD300A/TNFRSF14/HBEGF/PARP9/PRNP/VEGFA/TGFB1/NCF1/PTPN6/JAK2/IL6R/EHD4/SH2B3/ITGA5/ARHGEF2/PTK2B/PARP14/ABI1/PTPRJ/SOCS3/BST1/IQGAP1/TNFRSF1A/PAK2/ADAM17/HCLS1	46
GO:0031334	positive regulation of protein-containing complex assembly	43/1068	237/18722	1.21287403814054e-11	4.8840808282137e-10	ISG15/PLEK/PYCARD/LGALS3/LCP1/CLEC7A/MSN/GRB2/CD36/NCKAP1L/ACTR2/ACTR3/GMFG/RHOA/SYK/HSPA1A/CORO1A/ARPC3/TLR4/VEGFA/WAS/TGFB1/HCK/BID/GBP5/MYD88/VASP/PTK2B/FNIP2/ARPC4/ARPC1B/CYFIP1/RAC1/ATM/ABCA1/GSN/PAK1/ARPC5/BRK1/ARF6/FNIP1/BAX/PFN1	43
GO:0034121	regulation of toll-like receptor signaling pathway	23/1068	75/18722	1.34733492815607e-11	5.38534760913345e-10	CYBA/TREM2/CD36/ARRB2/LYN/CD300A/TLR2/TLR1/IRF7/RSAD2/IFI35/TLR5/CD300LF/NR1H3/LILRA2/IRAK3/TNFAIP3/NINJ1/IRF1/RTN4/PJA2/FLOT1/APPL1	23
GO:0045936	negative regulation of phosphate metabolic process	63/1068	441/18722	1.42563699939536e-11	5.656424447601e-10	APOE/APOC1/NUPR1/PLEK/SORL1/FBP1/DUSP1/PYCARD/LGALS3/SLC8A1/GADD45B/LILRB4/NCKAP1L/PTPRC/ARRB2/GNAI2/LYN/RB1/HGF/SAMSN1/CORO1C/CD300A/CIB1/SIRPA/PRNP/TGFB1/DDIT4/ENG/CSK/PTPN6/MYADM/RASSF2/SH2B3/SPRED1/IRAK3/LRRK2/PRKAG2/CDKN1A/PARP14/PTPRJ/SOCS3/IL1B/STAT3/TNFAIP3/LRP1/ADAR/PRKAR1A/DUSP3/CALM3/PAK2/ROCK1/PPP1R15A/APC/CEBPA/NUP62/DNAJC3/GNAQ/RGS2/BAX/WNK1/BOD1L1/YWHAG/PLEC	63
GO:0032102	negative regulation of response to external stimulus	61/1068	420/18722	1.50204620278112e-11	5.86542290589006e-10	APOE/SPP1/HLA-DRB1/HLA-A/HLA-B/GPX1/TREM2/CD9/AIF1/ACP5/GRN/HAMP/HLA-E/ISG15/SAMHD1/DUSP1/IFI16/ZFP36/HAVCR2/A2M/LGALS9/HLA-F/FGL2/PTPRC/ARRB2/LYN/RB1/HGF/METRNL/SYK/OAS1/SIRPA/LILRB1/PTGER4/TNFRSF1B/ALOX5/KLF4/STAT2/CARD16/HCK/PLAU/AOAH/VSIG4/NR1H3/OAS3/RIN3/SH2B3/RHBDF2/TNFAIP8L2/LILRA2/IRAK3/FGR/PARP14/SOCS3/SERPING1/TNFAIP3/HTRA1/ADAR/DUSP3/TNFRSF1A/PCBP2	61
GO:0002501	peptide antigen assembly with MHC protein complex	12/1068	18/18722	1.50860179439119e-11	5.86542290589006e-10	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQB1/HLA-DQA1/HLA-DMA/B2M/HLA-DMB/HLA-DQA2/HLA-DOA/HLA-DRB5	12
GO:0097529	myeloid leukocyte migration	41/1068	220/18722	1.51092250540904e-11	5.86542290589006e-10	CD74/FCER1G/TREM2/CD9/AIF1/CD81/CCL3/CCL3L3/ITGB2/LGMN/DUSP1/C5AR1/SPI1/LGALS3/CSF1R/C3AR1/PLA2G7/NCKAP1L/CKLF/LYN/PECAM1/CCL4/SYK/CD300A/SIRPA/PTGER4/RHOG/VEGFA/PREX1/CCR1/TREM1/CAMK1D/ADAM8/RIN3/IL6R/ADGRE2/MYD88/PTK2B/RAC1/BST1/VEGFB	41
GO:0010563	negative regulation of phosphorus metabolic process	63/1068	442/18722	1.57337992781609e-11	6.06425577892545e-10	APOE/APOC1/NUPR1/PLEK/SORL1/FBP1/DUSP1/PYCARD/LGALS3/SLC8A1/GADD45B/LILRB4/NCKAP1L/PTPRC/ARRB2/GNAI2/LYN/RB1/HGF/SAMSN1/CORO1C/CD300A/CIB1/SIRPA/PRNP/TGFB1/DDIT4/ENG/CSK/PTPN6/MYADM/RASSF2/SH2B3/SPRED1/IRAK3/LRRK2/PRKAG2/CDKN1A/PARP14/PTPRJ/SOCS3/IL1B/STAT3/TNFAIP3/LRP1/ADAR/PRKAR1A/DUSP3/CALM3/PAK2/ROCK1/PPP1R15A/APC/CEBPA/NUP62/DNAJC3/GNAQ/RGS2/BAX/WNK1/BOD1L1/YWHAG/PLEC	63
GO:0050672	negative regulation of lymphocyte proliferation	24/1068	83/18722	1.96941628425106e-11	7.53685834738916e-10	HLA-DRB1/GPNMB/TYROBP/CD86/HAVCR2/LST1/LGALS9/LILRB4/LYN/MNDA/IL4I1/CD300A/LILRB1/TNFRSF14/PRNP/LILRB2/PTPN6/BTK/VSIG4/SPN/INPP5D/CEBPB/ATM/PRKAR1A	24
GO:0070664	negative regulation of leukocyte proliferation	25/1068	90/18722	1.99634898374412e-11	7.58612613822764e-10	HLA-DRB1/GPNMB/TYROBP/CD86/HAVCR2/LST1/LGALS9/LILRB4/LYN/MNDA/IL4I1/CD300A/LILRB1/TNFRSF14/PRNP/LILRB2/PTPN6/BTK/VSIG4/SPN/INPP5D/TNFAIP3/CEBPB/ATM/PRKAR1A	25
GO:0062207	regulation of pattern recognition receptor signaling pathway	27/1068	105/18722	2.27875441773303e-11	8.59871247418702e-10	CYBA/TREM2/CD36/ARRB2/SLC15A3/LYN/CD300A/TLR2/HSPA1A/TLR4/TLR1/IRF7/RSAD2/IFI35/TLR5/CD300LF/NR1H3/LILRA2/IRAK3/TNFAIP3/NINJ1/IRF1/RTN4/PJA2/XIAP/FLOT1/APPL1	27
GO:0070997	neuron death	55/1068	361/18722	2.36892458537147e-11	8.87688684907253e-10	APOE/GPNMB/TYROBP/GPX1/TREM2/CTSZ/C1QA/CCL3/GRN/NUPR1/ITGB2/SORL1/SOD2/LGMN/FOS/PPT1/C5AR1/HMOX1/JUN/HIF1A/HLA-F/MEF2C/ARRB2/RB1/RHOA/NR4A2/REL/AXL/NAIP/CORO1A/TNFRSF1B/TLR4/PRNP/DDIT4/ITGAM/BID/JAK2/NQO2/ADAM8/TRPM2/NAMPT/LRRK2/PTK2B/BTG2/RAB29/MCL1/STAT3/LRP1/CEBPB/MAX/PICALM/CDC42/BAX/XIAP/EGR1	55
GO:0032945	negative regulation of mononuclear cell proliferation	24/1068	84/18722	2.60984747219244e-11	9.71223238617268e-10	HLA-DRB1/GPNMB/TYROBP/CD86/HAVCR2/LST1/LGALS9/LILRB4/LYN/MNDA/IL4I1/CD300A/LILRB1/TNFRSF14/PRNP/LILRB2/PTPN6/BTK/VSIG4/SPN/INPP5D/CEBPB/ATM/PRKAR1A	24
GO:0007249	I-kappaB kinase/NF-kappaB signaling	47/1068	281/18722	2.63155498129513e-11	9.72593882127981e-10	HLA-DRB1/CD74/LGALS1/TREM2/S100A4/BST2/MTDH/PYCARD/STAT1/LITAF/HMOX1/CLEC7A/LGALS9/LILRB4/CD36/CD4/FLNA/RHOA/TLR7/TRIM22/TLR2/REL/SIRPA/CASP1/TLR4/CARD16/CXXC5/IRAK1/BTK/TLR8/TRIM14/SECTM1/TNFSF10/MYD88/ATP2C1/TRIM38/IL1B/TNFAIP3/AZI2/NFKBIA/CARD19/TNFRSF1A/ROCK1/TAB2/NUP62/AKAP13/LTBR	47
GO:0034101	erythrocyte homeostasis	30/1068	129/18722	2.80567512733583e-11	1.02989272021117e-09	B2M/MAFB/ISG15/DNASE2/STAT1/ZFP36/HMOX1/SPI1/ID2/HIF1A/ZFP36L1/NCKAP1L/LYN/RB1/AXL/HSPA1A/VEGFA/JAK2/KLF2/IKZF1/SH2B3/BCL6/INPP5D/KMT2E/STAT3/ARID4A/ADAR/SMAP1/HCLS1/PTBP3	30
GO:0001906	cell killing	37/1068	188/18722	2.84822867603806e-11	1.03618191662918e-09	HLA-DRA/HLA-DRB1/TYROBP/HLA-A/HLA-B/B2M/C3/LYZ/HAMP/CTSH/HLA-E/SPI1/HAVCR2/CTSC/CLEC7A/IL18/LGALS9/HLA-F/NCKAP1L/PTPRC/ARRB2/SYK/CORO1A/LILRB1/P2RX7/SLAMF7/TREM1/ITGAM/PTPN6/MYD88/MR1/HPRT1/STXBP2/ARL8B/LAMP1/STX7/KIF5B	37
GO:0060759	regulation of response to cytokine stimulus	34/1068	162/18722	2.86121396548828e-11	1.03618191662918e-09	CD74/LAPTM5/TREM2/CXCR4/ISG15/SAMHD1/PYCARD/HIF1A/PTPRC/SYK/TLR2/OAS1/AXL/HSPA1A/CASP1/TLR4/KLF4/PARP9/STAT2/CARD16/AGPAT2/IRF7/IRAK1/PTPN6/CD300LF/NR1H3/OAS3/SH2B3/IRAK3/IFIH1/PARP14/TNFAIP3/ADAR/ADAM17	34
GO:0030833	regulation of actin filament polymerization	35/1068	171/18722	3.0904715692502e-11	1.11174563917827e-09	TMSB4X/CAPG/PYCARD/COTL1/GRB2/NCKAP1L/ACTR2/ACTR3/GMFG/RHOA/TMSB10/TWF2/CORO1A/ARPC3/WAS/PREX1/HCK/MYADM/VASP/PTK2B/ARHGAP18/ARPC4/ARPC1B/CAPZA2/CAPZA1/CYFIP1/GSN/FLII/ARPC5/HCLS1/BRK1/ARF6/DBNL/CAPZB/PFN1	35
GO:0001774	microglial cell activation	18/1068	47/18722	3.35394630517339e-11	1.19853604388845e-09	TYROBP/TREM2/AIF1/C1QA/CCL3/GRN/ITGB2/C5AR1/CTSC/IFNGR2/PTPRC/IFNGR1/TLR2/TLR1/ITGAM/JAK2/NAMPT/LRRK2	18
GO:0050868	negative regulation of T cell activation	29/1068	122/18722	3.38379783884829e-11	1.20124823279114e-09	HLA-DRB1/CD74/GPNMB/LAPTM5/CD86/LGALS3/HAVCR2/LGALS9/LILRB4/FGL2/NCKAP1L/IL4I1/CD300A/LILRB1/TNFRSF14/PRNP/LILRB2/PAG1/RUNX1/PTPN6/VSIG4/BCL6/TNFAIP8L2/SPN/CEBPB/PRKAR1A/DUSP3/IRF1/SOCS6	29
GO:0072659	protein localization to plasma membrane	47/1068	284/18722	3.84441856853148e-11	1.35584853567293e-09	TREM2/CD81/CCDC88A/LGALS3/ACTB/GBP1/VAMP5/FLNA/CIB1/RHOQ/RAP1A/RHOG/PRNP/GGA2/TGFB1/MYO5A/ABI3/CSK/MYADM/EHD4/ATP1B1/ATP2C1/RAP2A/GGA1/RAB8B/LRP1/EFR3A/TSPAN14/NUMB/STX4/TNFRSF1A/ROCK1/RILPL2/FCHO2/PICALM/ARF6/STX7/RAB10/FLOT1/RAB8A/APPL1/KIF5B/ATP1B3/PIK3R1/RAB7A/RAB13/S100A10	47
GO:0002262	myeloid cell homeostasis	33/1068	157/18722	5.35627811297984e-11	1.8767842011454e-09	B2M/MAFB/HAMP/ISG15/DNASE2/STAT1/ZFP36/HMOX1/SPI1/ID2/HIF1A/ZFP36L1/NCKAP1L/LYN/RB1/AXL/HSPA1A/VEGFA/JAK2/KLF2/IKZF1/SH2B3/BCL6/INPP5D/KMT2E/STAT3/ARID4A/ADAR/ADAM17/SMAP1/HCLS1/PTBP3/BAX	33
GO:0002456	T cell mediated immunity	27/1068	109/18722	5.8158131079795e-11	2.02465338907467e-09	HLA-DRA/HLA-DRB1/HLA-A/HLA-B/B2M/CD81/CTSH/HLA-E/CTSC/IL18/LILRB4/HLA-F/NCKAP1L/PTPRC/IL4I1/LILRB1/AHR/TNFRSF1B/WAS/RSAD2/SASH3/MYO1G/DENND1B/MR1/HPRT1/IL1B/STX7	27
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	9/1068	10/18722	5.88064945873938e-11	2.0341015691896e-09	CD81/HLA-DMB/APBB1IP/LGALS3/HAVCR2/LGALS9/FGL2/LILRB1/ITGAL	9
GO:0048771	tissue remodeling	35/1068	175/18722	6.10274840182359e-11	2.09395966434927e-09	SPP1/GPNMB/ACP5/TIMP1/CST3/LIPA/HAMP/SNX10/TPP1/CSF1R/IL18/HIF1A/MEF2C/FLNA/PDK4/SYK/AXL/P2RX7/TGFB1/TCIRG1/CSK/RUNX1/NOTCH2/GPR137B/ADAM8/RASSF2/MITF/MMP2/INPP5D/PTK2B/RAC1/ATP6AP1/TNFAIP3/ROCK1/BAX	35
GO:1903038	negative regulation of leukocyte cell-cell adhesion	31/1068	141/18722	6.13131258278696e-11	2.09395966434927e-09	HLA-DRB1/CD74/GPNMB/LAPTM5/CD86/LGALS3/HAVCR2/LGALS9/LILRB4/FGL2/NCKAP1L/IL4I1/CD300A/LILRB1/TNFRSF14/KLF4/PRNP/LILRB2/PAG1/RUNX1/PTPN6/VSIG4/BCL6/TNFAIP8L2/SPN/CEBPB/PRKAR1A/DUSP3/IRF1/WNK1/SOCS6	31
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	37/1068	193/18722	6.34197601010735e-11	2.1522831792792e-09	CD74/TREM2/CD81/FCGR1A/CD44/CLEC7A/CSF1R/IL18/CD36/PTPRC/ARRB2/LYN/HGF/PECAM1/CD4/SYK/TNFRSF14/HBEGF/PARP9/PRNP/VEGFA/TGFB1/NCF1/JAK2/IL6R/EHD4/ITGA5/ARHGEF2/PTK2B/PARP14/ABI1/PTPRJ/IQGAP1/TNFRSF1A/PAK2/ADAM17/HCLS1	37
GO:0036230	granulocyte activation	17/1068	43/18722	6.5026281810014e-11	2.19301135404272e-09	TYROBP/FCER1G/CCL3/GRN/ITGB2/SPI1/IL18/SYK/CD300A/PREX1/PTAFR/ITGAM/LILRA2/MYD88/KMT2E/STXBP2/STX4	17
GO:0070665	positive regulation of leukocyte proliferation	32/1068	150/18722	6.9647369821374e-11	2.33426836991388e-09	HLA-DPA1/CD74/HLA-DPB1/HLA-A/AIF1/CD81/HLA-DMB/HLA-E/BST2/TNFSF13B/PYCARD/CD86/HAVCR2/CSF1R/IL18/LGALS9/MEF2C/NCKAP1L/PTPRC/LYN/GPR183/SYK/CORO1A/TLR4/TGFBR2/LILRB2/SASH3/BCL6/MYD88/CDKN1A/IL1B/BST1	32
GO:0043410	positive regulation of MAPK cascade	65/1068	480/18722	7.10476693366833e-11	2.3665013811157e-09	APOE/HLA-DRB1/CD74/GPNMB/LAPTM5/TREM2/CD81/CCL3/CCL3L3/CD44/PYCARD/C5AR1/SPI1/HAVCR2/CLEC7A/CSF1R/GADD45B/LGALS9/CD36/TIMP2/PTPRC/ARRB2/GNAI2/GPR183/HGF/CD4/SDCBP/TAOK3/CCL4/SYK/MARCO/CIB1/RAP1A/TLR4/GLIPR2/VEGFA/CCR1/TGFB1/SCIMP/CSK/NCF1/IRAK1/NQO2/NOTCH2/ADAM8/RASSF2/LRRK2/MYD88/PTK2B/ADAM9/PTPRJ/IL1B/ATP6AP1/EIF2AK2/LRP1/IQGAP1/TGFBR1/ROCK1/PAK1/PJA2/LAMTOR2/AKAP13/CDC42/TAOK1/LTBR	65
GO:0032611	interleukin-1 beta production	27/1068	110/18722	7.29499999486607e-11	2.40023292514008e-09	TYROBP/TREM2/ACP5/CCL3/PYCARD/IFI16/CLEC7A/LGALS9/LILRB4/CD36/ARRB2/MNDA/LPL/SIRPA/CASP1/TLR4/P2RX7/CARD16/JAK2/GBP5/TLR8/LILRA2/CD33/MYD88/STAT3/TNFAIP3/EGR1	27
GO:0032651	regulation of interleukin-1 beta production	27/1068	110/18722	7.29499999486607e-11	2.40023292514008e-09	TYROBP/TREM2/ACP5/CCL3/PYCARD/IFI16/CLEC7A/LGALS9/LILRB4/CD36/ARRB2/MNDA/LPL/SIRPA/CASP1/TLR4/P2RX7/CARD16/JAK2/GBP5/TLR8/LILRA2/CD33/MYD88/STAT3/TNFAIP3/EGR1	27
GO:0050729	positive regulation of inflammatory response	31/1068	142/18722	7.42284019639378e-11	2.42749367877217e-09	TREM2/C3/CD81/CCL3/GRN/NUPR1/HLA-E/ALOX5AP/CTSC/IL18/PLA2G7/NEAT1/LPL/TLR7/TLR2/GPSM3/PTGER4/TLR4/IFI35/BTK/JAK2/ADAM8/LRRK2/MGST2/IL1B/NINJ1/NFKBIA/CEBPB/TNFRSF1A/NFKBIZ/CEBPA	31
GO:0002705	positive regulation of leukocyte mediated immunity	30/1068	134/18722	7.73196146219771e-11	2.51335325602523e-09	HLA-DRA/HLA-DRB1/TYROBP/HLA-A/HLA-B/B2M/TREM2/C3/CD81/HLA-E/ITGB2/SPI1/CLEC7A/IL18/HLA-F/PTPRC/TGFB1/SCIMP/PTAFR/RSAD2/ITGAM/BTK/SASH3/DENND1B/STAT6/MR1/IL1B/STX4/LAMP1/STX7	30
GO:0002706	regulation of lymphocyte mediated immunity	34/1068	168/18722	8.16627779053563e-11	2.63863682381618e-09	HLA-DRA/HLA-DRB1/HLA-A/HLA-B/B2M/TREM2/C3/CD81/HLA-E/HAVCR2/IL18/LGALS9/LILRB4/HLA-F/NCKAP1L/PTPRC/ARRB2/IL4I1/LILRB1/AHR/TNFRSF1B/WAS/TGFB1/RSAD2/PTPN6/BTK/SASH3/BCL6/DENND1B/STAT6/MR1/IL1B/LAMP1/STX7	34
GO:0045639	positive regulation of myeloid cell differentiation	26/1068	103/18722	8.35723733835257e-11	2.68426504034229e-09	HLA-DRB1/CD74/TYROBP/TREM2/ISG15/FOS/STAT1/ID2/EVI2B/JUN/HIF1A/ZFP36L1/NCKAP1L/RB1/CD4/HSPA1A/CCR1/TGFB1/RUNX1/NOTCH2/INPP5D/STAT3/ATP6AP1/SMAP1/HCLS1/KLF10	26
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	13/1068	24/18722	8.73909496097836e-11	2.79030511298457e-09	CD300A/TLR2/TLR4/TLR1/IRF7/IRAK1/BTK/TLR5/CD300LF/TLR8/IRAK3/MYD88/IRF1	13
GO:0042326	negative regulation of phosphorylation	56/1068	385/18722	9.82476440737995e-11	3.11849580836601e-09	APOE/NUPR1/SORL1/FBP1/DUSP1/PYCARD/SLC8A1/GADD45B/LILRB4/PTPRC/ARRB2/LYN/RB1/HGF/SAMSN1/CORO1C/CD300A/CIB1/SIRPA/PRNP/TGFB1/DDIT4/ENG/CSK/PTPN6/MYADM/RASSF2/SH2B3/SPRED1/IRAK3/LRRK2/PRKAG2/CDKN1A/PARP14/PTPRJ/SOCS3/IL1B/STAT3/TNFAIP3/LRP1/ADAR/PRKAR1A/DUSP3/CALM3/PAK2/ROCK1/APC/CEBPA/NUP62/DNAJC3/GNAQ/RGS2/BAX/WNK1/YWHAG/PLEC	56
GO:0008064	regulation of actin polymerization or depolymerization	36/1068	187/18722	1.01518534861609e-10	3.20347376674411e-09	TMSB4X/CAPG/PLEK/PYCARD/COTL1/GRB2/NCKAP1L/ACTR2/ACTR3/GMFG/RHOA/TMSB10/TWF2/CORO1A/ARPC3/WAS/PREX1/HCK/MYADM/VASP/PTK2B/ARHGAP18/ARPC4/ARPC1B/CAPZA2/CAPZA1/CYFIP1/GSN/FLII/ARPC5/HCLS1/BRK1/ARF6/DBNL/CAPZB/PFN1	36
GO:0002821	positive regulation of adaptive immune response	27/1068	112/18722	1.13781670461049e-10	3.56956915004548e-09	HLA-DRA/HLA-DRB1/HLA-A/HLA-B/B2M/TREM2/C3/CD81/HLA-E/TNFSF13B/PYCARD/CLEC7A/IL18/SLC11A1/HLA-F/PTPRC/CD4/TGFB1/RSAD2/BTK/SASH3/DENND1B/STAT6/MR1/IL1B/NFKBIZ/STX7	27
GO:0032612	interleukin-1 production	29/1068	128/18722	1.17680838683579e-10	3.63042922122107e-09	TYROBP/TREM2/ACP5/CCL3/PYCARD/IFI16/HAVCR2/CLEC7A/LGALS9/LILRB4/CD36/ARRB2/MNDA/LPL/SIRPA/CASP1/TLR4/P2RX7/CARD16/JAK2/GBP5/TLR8/LILRA2/CD33/MYD88/STAT3/TNFAIP3/TMED10/EGR1	29
GO:0032652	regulation of interleukin-1 production	29/1068	128/18722	1.17680838683579e-10	3.63042922122107e-09	TYROBP/TREM2/ACP5/CCL3/PYCARD/IFI16/HAVCR2/CLEC7A/LGALS9/LILRB4/CD36/ARRB2/MNDA/LPL/SIRPA/CASP1/TLR4/P2RX7/CARD16/JAK2/GBP5/TLR8/LILRA2/CD33/MYD88/STAT3/TNFAIP3/TMED10/EGR1	29
GO:0030218	erythrocyte differentiation	28/1068	120/18722	1.17740013660802e-10	3.63042922122107e-09	B2M/MAFB/ISG15/DNASE2/STAT1/ZFP36/SPI1/ID2/HIF1A/ZFP36L1/NCKAP1L/LYN/RB1/HSPA1A/VEGFA/JAK2/KLF2/IKZF1/SH2B3/BCL6/INPP5D/KMT2E/STAT3/ARID4A/ADAR/SMAP1/HCLS1/PTBP3	28
GO:0030832	regulation of actin filament length	36/1068	188/18722	1.18816593622426e-10	3.64280874537848e-09	TMSB4X/CAPG/PLEK/PYCARD/COTL1/GRB2/NCKAP1L/ACTR2/ACTR3/GMFG/RHOA/TMSB10/TWF2/CORO1A/ARPC3/WAS/PREX1/HCK/MYADM/VASP/PTK2B/ARHGAP18/ARPC4/ARPC1B/CAPZA2/CAPZA1/CYFIP1/GSN/FLII/ARPC5/HCLS1/BRK1/ARF6/DBNL/CAPZB/PFN1	36
GO:0002704	negative regulation of leukocyte mediated immunity	20/1068	63/18722	1.44115964599305e-10	4.39350138405564e-09	HLA-A/HLA-B/HLA-E/BST2/CD84/HMOX1/SPI1/HAVCR2/LGALS9/LILRB4/HLA-F/NCKAP1L/PTPRC/ARRB2/IL4I1/CD300A/LILRB1/AHR/PTPN6/BCL6	20
GO:0001818	negative regulation of cytokine production	53/1068	357/18722	1.46430392411749e-10	4.4389797609764e-09	HLA-DRB1/GPNMB/TYROBP/TMSB4X/LAPTM5/TREM2/ACP5/SRGN/TSPO/BST2/CD84/PYCARD/ZFP36/HMOX1/HAVCR2/CD83/SLC11A1/LGALS9/LILRB4/HLA-F/NCKAP1L/PTPRC/ARRB2/GBP1/HGF/HOMER3/OAS1/REL/AXL/SIRPA/LILRB1/PTGER4/TLR4/KLF4/PRNP/CARD16/TGFB1/CSK/PTPN6/BTK/VSIG4/KLF2/OAS3/BCL6/TLR8/CLEC4A/INPP5D/IRAK3/CD33/RAC1/TNFAIP3/RGCC/ADCY7	53
GO:0007265	Ras protein signal transduction	51/1068	337/18722	1.6259549364873e-10	4.90148203200305e-09	APOE/AIF1/GPR65/FBP1/ARHGDIB/GRB2/JUN/RAP2B/TIMP2/RB1/SDCBP/RHOA/LPAR6/RAP1A/RHOG/WAS/DOK3/MYO9B/NOTCH2/CYTH1/DOK2/CYTH4/BCL6/DOK1/ARHGAP4/RRAS/RIT1/ARHGEF2/RAP2A/GABARAP/CDKN1A/GNA13/CYFIP1/RALA/RAC1/SHTN1/ABCA1/ROCK1/GNB1/NUP62/ARHGAP24/RHOB/CFL1/BRK1/ARF6/AKAP13/CDC42/DBNL/FLOT1/ARHGDIA/KPNB1	51
GO:0002444	myeloid leukocyte mediated immunity	25/1068	99/18722	1.90677757835513e-10	5.71609545155792e-09	TYROBP/C3/CCL3/HLA-E/ITGB2/CD84/HMOX1/SPI1/LGALS9/LYN/SYK/LAT2/CD300A/TREM1/PTAFR/MILR1/ITGAM/BTK/ADGRE2/FGR/MYD88/KMT2E/STXBP2/STX4/ADAM17	25
GO:0030888	regulation of B cell proliferation	20/1068	64/18722	1.98480083463937e-10	5.9171189523282e-09	CD74/TYROBP/CD81/TNFSF13B/MEF2C/NCKAP1L/PTPRC/LYN/GPR183/MNDA/CD300A/AHR/TLR4/BTK/SASH3/BCL6/INPP5D/CDKN1A/BST1/ATM	20
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	26/1068	107/18722	2.08047218114342e-10	6.16825708211534e-09	HLA-DRA/HLA-DRB1/HLA-A/HLA-B/B2M/TREM2/C3/CD81/HLA-E/TNFSF13B/CLEC7A/IL18/SLC11A1/HLA-F/PTPRC/CD4/TGFB1/RSAD2/BTK/SASH3/DENND1B/STAT6/MR1/IL1B/NFKBIZ/STX7	26
GO:1901214	regulation of neuron death	49/1068	319/18722	2.20192996802186e-10	6.49268530461527e-09	APOE/GPNMB/TYROBP/TREM2/CTSZ/C1QA/CCL3/GRN/NUPR1/ITGB2/SORL1/SOD2/LGMN/FOS/PPT1/C5AR1/HMOX1/JUN/HIF1A/HLA-F/MEF2C/ARRB2/RHOA/NR4A2/REL/AXL/NAIP/CORO1A/TNFRSF1B/TLR4/PRNP/DDIT4/ITGAM/JAK2/NQO2/ADAM8/TRPM2/LRRK2/PTK2B/BTG2/RAB29/MCL1/STAT3/LRP1/CEBPB/PICALM/CDC42/BAX/EGR1	49
GO:1903900	regulation of viral life cycle	31/1068	148/18722	2.24569095099641e-10	6.57303870619433e-09	HLA-DRB1/CD74/LGALS1/BST2/ISG15/IFI16/MX1/IFITM3/LGALS9/CD4/PLSCR1/TRIM22/OAS1/AXL/IFIT1/OAS2/PABPC1/CIITA/RSAD2/OAS3/TRIM14/APOBEC3C/APOBEC3A/IFIH1/TRIM38/EIF2AK2/ADAR/DDX5/GSN/FAM111A/CHMP3	31
GO:0034340	response to type I interferon	19/1068	58/18722	2.25462777002383e-10	6.57303870619433e-09	IFI27/ISG15/SAMHD1/STAT1/MX1/IFITM3/OAS1/IFIT1/OAS2/JAK1/SP100/STAT2/IRF7/IRAK1/PTPN6/OAS3/MYD88/IFNAR1/ADAR	19
GO:0002709	regulation of T cell mediated immunity	23/1068	85/18722	2.26572498026713e-10	6.57303870619433e-09	HLA-DRA/HLA-DRB1/HLA-A/HLA-B/B2M/CD81/HLA-E/IL18/LILRB4/HLA-F/NCKAP1L/PTPRC/IL4I1/LILRB1/AHR/TNFRSF1B/WAS/RSAD2/SASH3/DENND1B/MR1/IL1B/STX7	23
GO:0043300	regulation of leukocyte degranulation	17/1068	46/18722	2.29519214410703e-10	6.62291808000082e-09	ITGB2/CD84/HMOX1/SPI1/LGALS9/HLA-F/NCKAP1L/LYN/SYK/CD300A/PTAFR/ITGAM/ADGRE2/FGR/STXBP2/STX4/LAMP1	17
GO:0070371	ERK1 and ERK2 cascade	50/1068	330/18722	2.35855736057254e-10	6.76956144555821e-09	APOE/HLA-DRB1/CD74/GPNMB/TREM2/CCL3/CCL3L3/CTSH/CD44/ZFP36L2/DUSP1/PYCARD/C5AR1/HAVCR2/CSF1R/LGALS9/CD36/ZFP36L1/PTPRC/ARRB2/GBP1/GNAI2/LYN/GPR183/CD4/CCL4/SYK/MARCO/CIB1/SIRPA/PTGER4/RAP1A/TLR4/KLF4/GLIPR2/CCR1/TGFB1/SCIMP/CSK/PTPN6/NQO2/NOTCH2/SPRED1/RRAS/PTK2B/IL1B/ATP6AP1/LRP1/DUSP3/ATF3	50
GO:0071357	cellular response to type I interferon	18/1068	52/18722	2.38610741743162e-10	6.81239980130212e-09	IFI27/ISG15/SAMHD1/STAT1/IFITM3/OAS1/IFIT1/OAS2/JAK1/SP100/STAT2/IRF7/IRAK1/PTPN6/OAS3/MYD88/IFNAR1/ADAR	18
GO:0071496	cellular response to external stimulus	49/1068	320/18722	2.46025723874784e-10	6.98713055804387e-09	CD68/CYBA/AIF1/GLUL/FOS/IFI16/HMOX1/MAP3K2/JUN/PTPRC/LYN/UPP1/LAMP2/UCP2/LPL/USF2/PDK4/ASGR1/TLR7/NR4A2/AXL/PTGER4/CASP1/TLR4/ENG/RRAGD/TLR5/NAMPT/ITGA4/TLR8/LRRK2/MYD88/PRKAG2/GABARAP/CDKN1A/IL1B/RAC1/EIF2AK2/SESN3/IRF1/TNFRSF1A/MAX/KLF10/FNIP1/LTBR/ATF3/ARHGDIA/ATP1A1/PLEC	49
GO:0097028	dendritic cell differentiation	17/1068	47/18722	3.40574406847447e-10	9.62167277145982e-09	HLA-B/TREM2/SPI1/TMEM176B/LGALS9/LYN/TMEM176A/AXL/LILRB1/IRF8/TGFBR2/LILRB2/NOTCH2/TRPM2/AZI2/CEBPB/LTBR	17
GO:0042119	neutrophil activation	15/1068	36/18722	3.58901054974125e-10	1.00343528116082e-08	TYROBP/FCER1G/GRN/ITGB2/SPI1/IL18/SYK/CD300A/PREX1/PTAFR/ITGAM/LILRA2/MYD88/KMT2E/STXBP2	15
GO:0071402	cellular response to lipoprotein particle stimulus	15/1068	36/18722	3.58901054974125e-10	1.00343528116082e-08	APOE/CD68/FCER1G/TREM2/CD9/CD81/ITGB2/CD36/LPL/SYK/TLR4/MYD88/ABCG1/ABCA1/ADAM17	15
GO:0032732	positive regulation of interleukin-1 production	21/1068	73/18722	3.9535446318551e-10	1.09965602234485e-08	TYROBP/CCL3/PYCARD/IFI16/HAVCR2/CLEC7A/LGALS9/CD36/MNDA/LPL/CASP1/TLR4/P2RX7/JAK2/GBP5/TLR8/LILRA2/MYD88/STAT3/TMED10/EGR1	21
GO:0032479	regulation of type I interferon production	24/1068	95/18722	4.35109383563807e-10	1.19788277230118e-08	ISG15/CD14/PYCARD/STAT1/HAVCR2/TLR7/SYK/TLR2/OAS1/REL/SIRPA/OAS2/LILRB1/IRF8/TLR4/IRF7/IRAK1/OAS3/TLR8/MYD88/IFIH1/RNF135/IRF1/FLOT1	24
GO:0032606	type I interferon production	24/1068	95/18722	4.35109383563807e-10	1.19788277230118e-08	ISG15/CD14/PYCARD/STAT1/HAVCR2/TLR7/SYK/TLR2/OAS1/REL/SIRPA/OAS2/LILRB1/IRF8/TLR4/IRF7/IRAK1/OAS3/TLR8/MYD88/IFIH1/RNF135/IRF1/FLOT1	24
GO:0033674	positive regulation of kinase activity	62/1068	467/18722	4.43746116709795e-10	1.21545890648023e-08	HLA-DRB1/CD74/TREM2/CD81/FCGR1A/CCDC88A/CD86/CSF1R/IL18/SLC11A1/NCKAP1L/PTPRC/LYN/CD4/TAOK3/RHOA/LCP2/SYK/CD300A/CIB1/AXL/RAP1A/TLR4/HBEGF/PRNP/VEGFA/DAZAP2/TGFB1/TGFBR2/CSK/NCF1/IRAK1/JAK2/ADAM8/RASSF2/IL6R/LRRK2/FGR/PRKAG2/OSBPL8/ACSL1/STK4/PTK2B/CDKN1A/ADAM9/ABI1/IL1B/RGCC/CALM3/IQGAP1/PAK2/CAB39/ADAM17/TAB2/PAK1/PPP2R3C/AKAP13/CDC42/TAOK1/WNK1/RANBP2/EGR1	62
GO:0051235	maintenance of location	49/1068	326/18722	4.731088439964e-10	1.28934107182049e-08	APOE/FTL/TMSB4X/MSR1/CYBA/TREM2/C3/FTH1/CCL3/SRGN/TSPO/PLIN2/SORL1/CCDC88A/SLC8A1/CHCHD10/CD36/PTPRC/SOAT1/LYN/CD4/FLNA/LPL/TMSB10/TWF2/CORO1A/VPS13C/SP100/PTPN6/NR1H3/TRPM2/NFKBIE/OSBPL8/PTK2B/MCOLN1/IL1B/ABCG1/NFKBIA/CPT1A/ERO1A/ABCA1/CALM3/GSTO1/GSN/ALKBH7/MORC3/GAA/BAX/GM2A	49
GO:0045621	positive regulation of lymphocyte differentiation	25/1068	104/18722	5.91200534295579e-10	1.59505904152947e-08	HLA-DRA/HLA-DRB1/CD74/CD86/IL18/CD83/LGALS9/LILRB4/NCKAP1L/PTPRC/RHOA/SYK/IL4I1/AXL/ZMIZ1/TGFBR2/LILRB2/RUNX1/BTK/ADAM8/SASH3/BCL6/INPP5D/NFKBIZ/PPP2R3C	25
GO:0046634	regulation of alpha-beta T cell activation	25/1068	104/18722	5.91200534295579e-10	1.59505904152947e-08	HLA-DRA/HLA-DRB1/HLA-A/CD81/HLA-E/CD86/IL18/CD83/LGALS9/LILRB4/NCKAP1L/PTPRC/RHOA/SYK/CD300A/LILRB1/TNFRSF14/TGFBR2/PRDM1/RUNX1/SASH3/BCL6/IRF1/HSPH1/NFKBIZ	25
GO:0032535	regulation of cellular component size	54/1068	382/18722	6.19997324091797e-10	1.66443062726335e-08	APOE/SPP1/TMSB4X/CAPG/PLEK/PYCARD/COTL1/MSN/GRB2/NCKAP1L/ACTR2/DPYSL2/ACTR3/GMFG/RHOA/TMEM123/TMSB10/TWF2/CORO1A/ARPC3/P2RX7/VEGFA/WAS/PREX1/HCK/MYADM/RIN3/ARHGAP4/VASP/PTK2B/ARHGAP18/ARPC4/ARPC1B/CAPZA2/CAPZA1/CYFIP1/RAC1/SHTN1/LRP1/LAMTOR4/RTN4/PPP1R15A/GSN/PAK1/FLII/ARPC5/HCLS1/BRK1/PICALM/ARF6/CHMP3/DBNL/CAPZB/PFN1	54
GO:0002440	production of molecular mediator of immune response	47/1068	308/18722	6.43878053941939e-10	1.71998315795579e-08	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/HLA-DQB1/HLA-DQA1/HLA-A/HLA-DMA/LAPTM5/B2M/CD81/HLA-DMB/HLA-E/BST2/HLA-DQA2/SAMHD1/CD86/HMOX1/CLEC7A/IL18/GAPT/LILRB4/CD36/HLA-F/PTPRC/TMBIM6/LILRB1/TNFRSF1B/TNFRSF14/HLA-DOA/TLR4/TGFB1/TREM1/SCIMP/RSAD2/BTK/HLA-DRB5/SASH3/BCL6/IRAK3/DENND1B/STAT6/LACC1/ERCC1/IL1B/STX4	47
GO:0050671	positive regulation of lymphocyte proliferation	29/1068	137/18722	6.56540683935999e-10	1.74516922685648e-08	HLA-DPA1/CD74/HLA-DPB1/HLA-A/AIF1/CD81/HLA-DMB/HLA-E/TNFSF13B/PYCARD/CD86/HAVCR2/IL18/LGALS9/MEF2C/NCKAP1L/PTPRC/GPR183/SYK/CORO1A/TLR4/TGFBR2/LILRB2/SASH3/BCL6/MYD88/CDKN1A/IL1B/BST1	29
GO:0034142	toll-like receptor 4 signaling pathway	16/1068	43/18722	6.92493545179943e-10	1.83171331852499e-08	TREM2/LY96/CD14/LYN/OAS1/TLR4/PIK3AP1/SCIMP/IFI35/IRAK1/NR1H3/LILRA2/TNFAIP3/NINJ1/NFKBIA/APPL1	16
GO:0002700	regulation of production of molecular mediator of immune response	32/1068	164/18722	7.75590492815357e-10	2.04150551182032e-08	CD74/HLA-A/LAPTM5/B2M/CD81/HLA-E/BST2/CD86/HMOX1/CLEC7A/IL18/LILRB4/CD36/HLA-F/PTPRC/TMBIM6/LILRB1/TNFRSF1B/TNFRSF14/TLR4/TGFB1/SCIMP/RSAD2/BTK/SASH3/BCL6/IRAK3/DENND1B/STAT6/LACC1/IL1B/STX4	32
GO:0032946	positive regulation of mononuclear cell proliferation	29/1068	138/18722	7.86683214791025e-10	2.06065176068562e-08	HLA-DPA1/CD74/HLA-DPB1/HLA-A/AIF1/CD81/HLA-DMB/HLA-E/TNFSF13B/PYCARD/CD86/HAVCR2/IL18/LGALS9/MEF2C/NCKAP1L/PTPRC/GPR183/SYK/CORO1A/TLR4/TGFBR2/LILRB2/SASH3/BCL6/MYD88/CDKN1A/IL1B/BST1	29
GO:0032731	positive regulation of interleukin-1 beta production	19/1068	62/18722	8.1947910911167e-10	2.13618805447661e-08	TYROBP/CCL3/PYCARD/IFI16/CLEC7A/LGALS9/CD36/MNDA/LPL/CASP1/TLR4/P2RX7/JAK2/GBP5/TLR8/LILRA2/MYD88/STAT3/EGR1	19
GO:0001933	negative regulation of protein phosphorylation	50/1068	342/18722	8.37585067793692e-10	2.17288895471864e-08	APOE/SORL1/DUSP1/PYCARD/SLC8A1/GADD45B/LILRB4/PTPRC/ARRB2/LYN/RB1/HGF/SAMSN1/CORO1C/CD300A/CIB1/SIRPA/PRNP/TGFB1/DDIT4/ENG/PTPN6/MYADM/RASSF2/SH2B3/SPRED1/IRAK3/LRRK2/PRKAG2/CDKN1A/PARP14/PTPRJ/SOCS3/IL1B/TNFAIP3/LRP1/ADAR/PRKAR1A/DUSP3/CALM3/PAK2/APC/CEBPA/NUP62/DNAJC3/GNAQ/RGS2/BAX/YWHAG/PLEC	50
GO:0030100	regulation of endocytosis	37/1068	211/18722	8.89316900637735e-10	2.2960545434647e-08	APOE/APOC1/B2M/TREM2/C3/CD14/PPT1/CD63/LGALS3/BMP2K/CD36/NCKAP1L/ARRB2/SDCBP/SYK/CD300A/AXL/LILRB1/VEGFA/MCTP1/NR1H3/RIN3/EHD4/LRRK2/RAC1/LRP1/NUMB/CALM3/ROCK1/SMAP1/RAB5C/PICALM/ARF6/CDC42/FLOT1/APPL1/ZFYVE16	37
GO:0002688	regulation of leukocyte chemotaxis	27/1068	122/18722	8.95270167953756e-10	2.30041801251356e-08	CD74/AIF1/CCL3/LGMN/DUSP1/C5AR1/SPI1/CSF1R/C3AR1/LGALS9/PLA2G7/NCKAP1L/LYN/CCL4/GPSM3/VEGFA/CCR1/CAMK1D/RIN3/IL6R/PTK2B/RAC1/BST1/VEGFB/ADAM17/ADAM10/WNK1	27
GO:0018108	peptidyl-tyrosine phosphorylation	53/1068	375/18722	9.01516483470822e-10	2.30548954730263e-08	CD74/TREM2/CD81/ITGB2/FCGR1A/CD44/CLEC7A/CSF1R/IL18/LILRB4/CD36/RAP2B/PTPRC/ARRB2/LYN/HGF/PECAM1/CD4/SAMSN1/SYK/CD300A/AXL/TNFRSF14/JAK1/HBEGF/PARP9/PRNP/VEGFA/TGFB1/HCK/CSK/NCF1/PTPN6/BTK/JAK2/IL6R/EHD4/SH2B3/ITGA5/FGR/ARHGEF2/PTK2B/PARP14/ABI1/PTPRJ/SOCS3/EIF2AK2/BST1/IQGAP1/TNFRSF1A/PAK2/ADAM17/HCLS1	53
GO:0045619	regulation of lymphocyte differentiation	33/1068	174/18722	9.11347395643108e-10	2.31963705041991e-08	HLA-DRA/HLA-DRB1/CD74/ZFP36L2/CD86/ID2/IL18/CD83/LGALS9/LILRB4/ZFP36L1/FGL2/NCKAP1L/PTPRC/RHOA/SYK/IL4I1/AXL/HLA-DOA/ZMIZ1/TGFBR2/LILRB2/PRDM1/RUNX1/PTPN6/BTK/ADAM8/SASH3/BCL6/INPP5D/IRF1/NFKBIZ/PPP2R3C	33
GO:0002286	T cell activation involved in immune response	26/1068	114/18722	9.17783274439183e-10	2.3250509619126e-08	HLA-DRA/HLA-DRB1/CD74/FCER1G/CD81/HLA-DMB/APBB1IP/CD86/LGALS3/LCP1/HAVCR2/IL18/SLC11A1/LGALS9/FGL2/NCKAP1L/GPR183/LILRB1/PTGER4/IL6R/BCL6/SPN/ITGAL/STAT6/STAT3/NFKBIZ	26
GO:0002886	regulation of myeloid leukocyte mediated immunity	18/1068	56/18722	9.55074139444838e-10	2.40821497964689e-08	TYROBP/C3/HLA-E/ITGB2/CD84/HMOX1/SPI1/LGALS9/LYN/SYK/CD300A/PTAFR/ITGAM/BTK/ADGRE2/FGR/STXBP2/STX4	18
GO:0002483	antigen processing and presentation of endogenous peptide antigen	11/1068	19/18722	9.79828931874468e-10	2.45914275181146e-08	HLA-DRA/HLA-DRB1/HLA-A/HLA-B/HLA-C/B2M/HLA-E/HLA-F/TAPBP/TAP1/ERAP2	11
GO:1990778	protein localization to cell periphery	49/1068	333/18722	9.89919994750836e-10	2.47296680170162e-08	TREM2/CD81/CCDC88A/LGALS3/ACTB/GBP1/VAMP5/FLNA/CIB1/RHOQ/RAP1A/RHOG/PRNP/GGA2/TGFB1/MYO5A/ABI3/CSK/MYADM/EHD4/ATP1B1/ATP2C1/RAP2A/GGA1/RAB29/RAB8B/LRP1/EFR3A/TSPAN14/NUMB/STX4/TNFRSF1A/ROCK1/RILPL2/ADAM10/FCHO2/PICALM/ARF6/STX7/RAB10/FLOT1/RAB8A/APPL1/KIF5B/ATP1B3/PIK3R1/RAB7A/RAB13/S100A10	49
GO:0060337	type I interferon signaling pathway	17/1068	50/18722	1.03959782275009e-09	2.58510131408271e-08	IFI27/ISG15/SAMHD1/STAT1/IFITM3/OAS1/OAS2/JAK1/SP100/STAT2/IRF7/IRAK1/PTPN6/OAS3/MYD88/IFNAR1/ADAR	17
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	13/1068	28/18722	1.05784289715981e-09	2.61840379498824e-08	HLA-A/HLA-B/HLA-C/FCER1G/B2M/HLA-E/IFI30/HLA-F/TAPBP/TAP1/CLEC4A/ERAP2/MR1	13
GO:0031532	actin cytoskeleton reorganization	25/1068	107/18722	1.12378290760747e-09	2.76891898148399e-08	GPR65/PLEK/CSF1R/ARHGDIB/GRB2/PHACTR1/FLNA/GMFG/RHOA/PARVG/HCK/ABI3/NOTCH2/TRPM2/ATP2C1/RAP2A/PTK2B/ARAP1/RALA/GSN/PAK1/HCLS1/CDC42/ARHGDIA/PLEC	25
GO:0042060	wound healing	57/1068	422/18722	1.18550288891969e-09	2.90771526755029e-08	APOE/FCER1G/GPX1/CD9/TIMP1/CXCR4/PLAUR/CD44/PLEK/SERPINA1/HMOX1/CLEC7A/ACTB/SLC11A1/CD36/RAP2B/HIF1A/LYN/FLNA/PLSCR1/RHOA/SYK/FERMT3/AXL/ALOX5/TLR4/HBEGF/VEGFA/ELK3/WAS/TGFB1/HPSE/TGFBR2/PLAU/PTPN6/JAK2/NOTCH2/SH2B3/ENTPD1/ITGA5/TLN1/CDKN1A/VKORC1/PRCP/JMJD1C/SERPING1/TNFAIP3/PABPC4/TGFBR1/ARL8B/ADAM17/PAK1/ARHGAP24/CLIC1/GNAQ/FGFR1OP2/PLEC	57
GO:0018212	peptidyl-tyrosine modification	53/1068	378/18722	1.20325001971785e-09	2.93789009339255e-08	CD74/TREM2/CD81/ITGB2/FCGR1A/CD44/CLEC7A/CSF1R/IL18/LILRB4/CD36/RAP2B/PTPRC/ARRB2/LYN/HGF/PECAM1/CD4/SAMSN1/SYK/CD300A/AXL/TNFRSF14/JAK1/HBEGF/PARP9/PRNP/VEGFA/TGFB1/HCK/CSK/NCF1/PTPN6/BTK/JAK2/IL6R/EHD4/SH2B3/ITGA5/FGR/ARHGEF2/PTK2B/PARP14/ABI1/PTPRJ/SOCS3/EIF2AK2/BST1/IQGAP1/TNFRSF1A/PAK2/ADAM17/HCLS1	53
GO:0001959	regulation of cytokine-mediated signaling pathway	30/1068	150/18722	1.413194757792e-09	3.43495446533586e-08	CD74/LAPTM5/TREM2/CXCR4/ISG15/SAMHD1/PYCARD/HIF1A/PTPRC/SYK/OAS1/AXL/HSPA1A/CASP1/PARP9/STAT2/CARD16/AGPAT2/IRF7/IRAK1/PTPN6/CD300LF/NR1H3/OAS3/SH2B3/IRAK3/PARP14/TNFAIP3/ADAR/ADAM17	30
GO:0002833	positive regulation of response to biotic stimulus	32/1068	168/18722	1.46096266764215e-09	3.53513657156818e-08	HLA-DRB1/TYROBP/CYBA/GRN/LY96/HLA-E/PYCARD/IFI16/LY86/SPI1/HAVCR2/CLEC7A/HLA-F/LYN/MNDA/PLSCR1/SYK/TLR4/CD180/PARP9/HCK/IRF7/SCIMP/IFI35/ADAM8/GBP5/TLR8/LILRA2/MR1/PAK2/PAK1/LAMP1	32
GO:0045670	regulation of osteoclast differentiation	19/1068	64/18722	1.49644717434832e-09	3.60483435392121e-08	TYROBP/TREM2/MAFB/CCL3/FOS/LILRB4/LILRB1/TLR4/CCR1/LILRB3/NOTCH2/GPR137B/RASSF2/MITF/INPP5D/ATP6AP1/CEBPB/KLF10/PIK3R1	19
GO:1901653	cellular response to peptide	51/1068	359/18722	1.56810247465416e-09	3.76065820143726e-08	VIM/CYBA/TREM2/SORL1/LGMN/STAT1/GRB2/CD36/ZFP36L1/GNAI2/LYN/UCP2/LPL/PDK4/NR4A2/RHOQ/TLR4/KLF4/PRNP/MYO5A/CSK/JAK2/KLF2/NAMPT/STAT5A/ITGA4/AGTRAP/OSBPL8/ARHGEF2/STAT6/RAB8B/SOCS3/IL1B/CYFIP1/STAT3/LRP1/SESN3/ROCK1/APC/PAK1/MAX/NR4A1/PKM/KLF10/RAB10/RAB8A/APPL1/PIK3R1/YWHAG/ZNF106/RAB13	51
GO:0002763	positive regulation of myeloid leukocyte differentiation	18/1068	58/18722	1.81541975545554e-09	4.31542070503881e-08	HLA-DRB1/CD74/TYROBP/TREM2/FOS/ID2/EVI2B/JUN/ZFP36L1/RB1/CD4/CCR1/TGFB1/RUNX1/NOTCH2/ATP6AP1/HCLS1/KLF10	18
GO:0032481	positive regulation of type I interferon production	18/1068	58/18722	1.81541975545554e-09	4.31542070503881e-08	ISG15/CD14/STAT1/TLR7/SYK/TLR2/OAS1/OAS2/TLR4/IRF7/IRAK1/OAS3/TLR8/MYD88/IFIH1/RNF135/IRF1/FLOT1	18
GO:0052547	regulation of peptidase activity	60/1068	461/18722	1.85105258472329e-09	4.38082445051179e-08	CTSD/LAPTM5/GPX1/C3/CSTB/TIMP1/GRN/CST3/PLAUR/CTSH/BST2/CD44/SORL1/LGMN/PYCARD/IFI16/PSMB9/SERPINA1/CLEC7A/A2M/LGALS9/PSMB8/TIMP2/ARRB2/LYN/HGF/RHOA/SYK/NAIP/MBP/CASP1/KLF4/PRNP/VEGFA/CARD16/BID/JAK2/RPS6KA1/APH1B/TNFSF10/CSTA/STAT3/SERPINB8/SERPING1/RPS27L/LRP1/DAPK1/RPS6KA3/PAK2/ROCK1/GSN/SVBP/NR4A1/TMED10/PICALM/FNIP1/HERPUD1/BAX/XIAP/PSME2	60
GO:0016064	immunoglobulin mediated immune response	36/1068	207/18722	1.89107896573723e-09	4.4560096502699e-08	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/HLA-DQB1/HLA-DQA1/HLA-DMA/FCER1G/B2M/C1QB/TREM2/C3/C1QA/CD81/HLA-DMB/C1QC/HLA-E/HLA-DQA2/GAPT/PTPRC/HLA-DOA/C2/TGFB1/TCIRG1/IRF7/PTPN6/BTK/HLA-DRB5/BCL6/TLR8/INPP5D/MYD88/STAT6/ERCC1/SERPING1	36
GO:0002690	positive regulation of leukocyte chemotaxis	23/1068	94/18722	1.97600690093249e-09	4.63588401627465e-08	CD74/AIF1/CCL3/LGMN/C5AR1/SPI1/CSF1R/C3AR1/LGALS9/PLA2G7/NCKAP1L/CCL4/GPSM3/VEGFA/CCR1/CAMK1D/IL6R/PTK2B/RAC1/VEGFB/ADAM17/ADAM10/WNK1	23
GO:0002720	positive regulation of cytokine production involved in immune response	19/1068	65/18722	2.0024221699957e-09	4.65735777124861e-08	CD74/HLA-A/LAPTM5/B2M/CD81/HLA-E/CLEC7A/IL18/CD36/HLA-F/LILRB1/TNFRSF14/TLR4/SCIMP/RSAD2/SASH3/DENND1B/LACC1/IL1B	19
GO:0071677	positive regulation of mononuclear cell migration	19/1068	65/18722	2.0024221699957e-09	4.65735777124861e-08	AIF1/CCL3/LGMN/PYCARD/SPI1/LGALS3/LGALS9/PLA2G7/CCL4/RHOA/TNFRSF14/CCR1/ADAM8/ITGA4/SPN/PTK2B/ADAM17/ADAM10/WNK1	19
GO:0070372	regulation of ERK1 and ERK2 cascade	46/1068	309/18722	2.21149846030428e-09	5.1215646745931e-08	APOE/HLA-DRB1/CD74/GPNMB/TREM2/CCL3/CCL3L3/CD44/DUSP1/PYCARD/C5AR1/HAVCR2/CSF1R/LGALS9/CD36/PTPRC/ARRB2/GBP1/GNAI2/LYN/GPR183/CD4/CCL4/SYK/MARCO/CIB1/SIRPA/RAP1A/TLR4/KLF4/GLIPR2/CCR1/TGFB1/SCIMP/CSK/PTPN6/NQO2/NOTCH2/SPRED1/RRAS/PTK2B/IL1B/ATP6AP1/LRP1/DUSP3/ATF3	46
GO:1902905	positive regulation of supramolecular fiber organization	36/1068	209/18722	2.47399651973796e-09	5.70499368397694e-08	APOE/GPX1/GPR65/PLEK/PYCARD/CCDC88A/GRB2/NCKAP1L/RB1/ACTR2/ACTR3/FLNA/GMFG/RHOA/HSPA1A/CORO1A/ARPC3/WAS/HCK/COLGALT1/VASP/PTK2B/ARPC4/ARPC1B/CYFIP1/RAC1/RGCC/TGFBR1/GSN/PAK1/ARPC5/BRK1/ARF6/CDC42/PFN1/S100A10	36
GO:0045860	positive regulation of protein kinase activity	53/1068	386/18722	2.55008783639569e-09	5.85543572986858e-08	FCGR1A/CCDC88A/CD86/CSF1R/IL18/SLC11A1/NCKAP1L/PTPRC/CD4/TAOK3/RHOA/LCP2/SYK/CD300A/CIB1/RAP1A/TLR4/HBEGF/PRNP/VEGFA/DAZAP2/TGFB1/TGFBR2/CSK/NCF1/IRAK1/JAK2/ADAM8/RASSF2/IL6R/LRRK2/PRKAG2/OSBPL8/ACSL1/STK4/PTK2B/CDKN1A/ADAM9/ABI1/IL1B/RGCC/CALM3/IQGAP1/PAK2/CAB39/ADAM17/TAB2/PAK1/PPP2R3C/AKAP13/TAOK1/WNK1/EGR1	53
GO:0097191	extrinsic apoptotic signaling pathway	37/1068	219/18722	2.58095680087214e-09	5.90120461758733e-08	GPX1/IFI27/PYCARD/HMOX1/SPI1/LGALS3/SKIL/PTPRC/BCL2A1/HGF/PEA15/CIB1/HSPA1A/TNFRSF1B/P2RX7/SP100/TNFSF12/TGFB1/BID/JAK2/IL6R/TNFSF10/STK4/ARHGEF2/GABARAP/MCL1/IL1B/TNFAIP3/STX4/BLOC1S2/TGFBR1/TNFRSF1A/PAK2/BAX/LTBR/ATF3/PIK3R1	37
GO:0050766	positive regulation of phagocytosis	19/1068	66/18722	2.66283084897913e-09	6.06271530003855e-08	FCER1G/CYBA/TREM2/C3/PYCARD/CLEC7A/SLC11A1/CD36/NCKAP1L/PTPRC/SIRPA/DOCK2/RAP1A/C2/CAMK1D/CD300LF/PTPRJ/IL1B/LRP1	19
GO:0019724	B cell mediated immunity	36/1068	210/18722	2.82551178282034e-09	6.40607629415906e-08	HLA-DRA/HLA-DRB1/HLA-DPA1/CD74/HLA-DPB1/HLA-DQB1/HLA-DQA1/HLA-DMA/FCER1G/B2M/C1QB/TREM2/C3/C1QA/CD81/HLA-DMB/C1QC/HLA-E/HLA-DQA2/GAPT/PTPRC/HLA-DOA/C2/TGFB1/TCIRG1/IRF7/PTPN6/BTK/HLA-DRB5/BCL6/TLR8/INPP5D/MYD88/STAT6/ERCC1/SERPING1	36
GO:0052548	regulation of endopeptidase activity	57/1068	432/18722	2.85384929716017e-09	6.44325138388129e-08	CTSD/LAPTM5/GPX1/C3/CSTB/TIMP1/CST3/PLAUR/CTSH/BST2/CD44/SORL1/LGMN/PYCARD/IFI16/PSMB9/SERPINA1/CLEC7A/A2M/LGALS9/PSMB8/TIMP2/ARRB2/LYN/HGF/RHOA/SYK/NAIP/MBP/CASP1/KLF4/PRNP/VEGFA/CARD16/BID/JAK2/RPS6KA1/APH1B/TNFSF10/CSTA/STAT3/SERPINB8/SERPING1/RPS27L/DAPK1/RPS6KA3/PAK2/ROCK1/GSN/NR4A1/TMED10/PICALM/FNIP1/HERPUD1/BAX/XIAP/PSME2	57
GO:0046635	positive regulation of alpha-beta T cell activation	19/1068	67/18722	3.51983376841172e-09	7.91375958931236e-08	HLA-DRA/HLA-DRB1/HLA-A/CD81/HLA-E/CD86/IL18/CD83/LGALS9/LILRB4/NCKAP1L/PTPRC/RHOA/SYK/TGFBR2/RUNX1/SASH3/HSPH1/NFKBIZ	19
GO:0032271	regulation of protein polymerization	38/1068	232/18722	3.85151928106066e-09	8.62356765170261e-08	TMSB4X/CAPG/PYCARD/COTL1/GRB2/NCKAP1L/ACTR2/ACTR3/GMFG/RHOA/TMSB10/TWF2/HSPA1A/CORO1A/ARPC3/WAS/PREX1/HCK/MYADM/VASP/PTK2B/ARHGAP18/ARPC4/ARPC1B/CAPZA2/CAPZA1/CYFIP1/RAC1/GSN/PAK1/FLII/ARPC5/HCLS1/BRK1/ARF6/DBNL/CAPZB/PFN1	38
GO:0046849	bone remodeling	22/1068	90/18722	4.51020206359136e-09	1.00566323698921e-07	SPP1/ACP5/HAMP/SNX10/TPP1/CSF1R/PDK4/SYK/P2RX7/TGFB1/TCIRG1/CSK/NOTCH2/GPR137B/ADAM8/RASSF2/MITF/INPP5D/PTK2B/RAC1/ATP6AP1/TNFAIP3	22
GO:0019883	antigen processing and presentation of endogenous antigen	12/1068	26/18722	5.12158278388276e-09	1.13728644863504e-07	HLA-DRA/HLA-DRB1/CD74/HLA-A/HLA-B/HLA-C/B2M/HLA-E/HLA-F/TAPBP/TAP1/ERAP2	12
GO:0071675	regulation of mononuclear cell migration	25/1068	115/18722	5.52755703431782e-09	1.22240564578602e-07	AIF1/CCL3/LGMN/DUSP1/PYCARD/C5AR1/SPI1/LGALS3/CSF1R/MSN/C3AR1/LGALS9/PLA2G7/LYN/CCL4/RHOA/TNFRSF14/CCR1/ADAM8/ITGA4/SPN/PTK2B/ADAM17/ADAM10/WNK1	25
GO:0007229	integrin-mediated signaling pathway	24/1068	107/18722	5.7662918906007e-09	1.26999636904822e-07	TIMP1/ITGB2/ISG15/LIMS1/PLEK/CD63/FLNA/SYK/FERMT3/ITGAX/ZYX/HCK/ITGAM/ITGA4/ITGAL/ITGA5/FGR/TLN1/PTK2B/ADAM9/BST1/ADAM10/CDC42/RCC2	24
GO:0042100	B cell proliferation	23/1068	99/18722	5.81718592040243e-09	1.27599736693055e-07	CD74/TYROBP/CD81/TNFSF13B/GAPT/MEF2C/NCKAP1L/PTPRC/LYN/GPR183/MNDA/CD300A/AHR/TLR4/CD180/BTK/SASH3/BCL6/INPP5D/CDKN1A/BST1/ATM/BAX	23
GO:0050921	positive regulation of chemotaxis	28/1068	141/18722	5.86429483429352e-09	1.28112287149181e-07	CD74/TMSB4X/TREM2/AIF1/CCL3/CXCR4/LGMN/C5AR1/SPI1/CSF1R/C3AR1/LGALS9/PLA2G7/NCKAP1L/CCL4/GPSM3/VEGFA/CCR1/TGFB1/CAMK1D/IL6R/PTK2B/RAC1/VEGFB/STX4/ADAM17/ADAM10/WNK1	28
GO:0032757	positive regulation of interleukin-8 production	18/1068	62/18722	6.00223342199944e-09	1.3059698203673e-07	CD74/CD14/PYCARD/CLEC7A/LGALS9/TLR7/SYK/TLR2/HSPA1A/TLR4/TLR1/CD58/TLR5/TLR8/LILRA2/MYD88/IL1B/STAT3	18
GO:0022604	regulation of cell morphogenesis	45/1068	309/18722	6.63379956165613e-09	1.43758965601191e-07	CCL3/CXCR4/ITGB2/LIMS1/CD44/LST1/CSF1R/MSN/PLEKHO1/GBP1/ACTR2/PLXNC1/FLNA/RHOA/CORO1C/CIB1/CORO1A/RHOQ/RHOG/FMNL1/VEGFA/PREX1/PLXND1/HCK/FGD4/MYADM/FMNL3/ARHGAP15/FGR/ITSN2/PTK2B/ARHGAP18/ARAP1/CYFIP1/RAC1/SH3KBP1/RHOB/CFL1/CDC42/RCC2/DBNL/ARHGDIA/FMNL2/CAPZB/S100A10	45
GO:0048525	negative regulation of viral process	22/1068	92/18722	7.00757668131517e-09	1.51251535089507e-07	BST2/ISG15/IFI16/STAT1/ZFP36/MX1/IFITM3/PLSCR1/OAS1/IFIT1/OAS2/CIITA/RSAD2/OAS3/TRIM14/APOBEC3C/APOBEC3A/IFIH1/EIF2AK2/GSN/FAM111A/CHMP3	22
GO:0050864	regulation of B cell activation	34/1068	198/18722	7.41934764823551e-09	1.59352449805375e-07	CD74/TYROBP/LAPTM5/CD81/ZFP36L2/TNFSF13B/ID2/MEF2C/ZFP36L1/NCKAP1L/PTPRC/LYN/GPR183/SAMSN1/MNDA/SYK/IL4I1/CD300A/AHR/TLR4/TGFB1/THEMIS2/PTPN6/BTK/SASH3/BCL6/INPP5D/CDKN1A/STAT6/SH3KBP1/TNFAIP3/BST1/ATM/PPP2R3C	34
GO:0032608	interferon-beta production	17/1068	56/18722	7.47149180888806e-09	1.59352449805375e-07	ISG15/PYCARD/TLR7/TLR2/OAS1/REL/SIRPA/OAS2/LILRB1/TLR4/IRF7/OAS3/TLR8/IFIH1/RNF135/IRF1/FLOT1	17
GO:0032648	regulation of interferon-beta production	17/1068	56/18722	7.47149180888806e-09	1.59352449805375e-07	ISG15/PYCARD/TLR7/TLR2/OAS1/REL/SIRPA/OAS2/LILRB1/TLR4/IRF7/OAS3/TLR8/IFIH1/RNF135/IRF1/FLOT1	17
GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	19/1068	70/18722	7.85771209262817e-09	1.66929978156778e-07	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQB1/HLA-DQA1/HLA-DMA/B2M/HLA-DMB/HLA-DQA2/GAPT/PTPRC/HLA-DOA/TGFB1/BTK/HLA-DRB5/BCL6/STAT6/ERCC1	19
GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	39/1068	249/18722	8.78987900760617e-09	1.86000733823698e-07	HLA-DRB1/CD74/LGALS1/TREM2/S100A4/BST2/MTDH/PYCARD/STAT1/LITAF/HMOX1/CLEC7A/LGALS9/LILRB4/CD36/CD4/FLNA/RHOA/TRIM22/REL/CASP1/TLR4/CARD16/CXXC5/IRAK1/TRIM14/SECTM1/TNFSF10/MYD88/ATP2C1/TRIM38/IL1B/TNFAIP3/CARD19/TNFRSF1A/TAB2/NUP62/AKAP13/LTBR	39
GO:0002283	neutrophil activation involved in immune response	10/1068	18/18722	1.00662808319514e-08	2.11746436392619e-07	TYROBP/FCER1G/ITGB2/SPI1/SYK/PTAFR/ITGAM/LILRA2/MYD88/STXBP2	10
GO:0060760	positive regulation of response to cytokine stimulus	17/1068	57/18722	1.00850322744446e-08	2.11746436392619e-07	CD74/LAPTM5/TREM2/CXCR4/HIF1A/TLR2/AXL/HSPA1A/CASP1/TLR4/PARP9/AGPAT2/IRF7/CD300LF/IFIH1/PARP14/ADAM17	17
GO:0002431	Fc receptor mediated stimulatory signaling pathway	13/1068	33/18722	1.23897302738577e-08	2.58684803237368e-07	FCER1G/PTPRC/LYN/PLSCR1/SYK/RAP1A/HCK/CSK/MYO1G/FGR/PTPRJ/PAK1/APPL1	13
GO:0071900	regulation of protein serine/threonine kinase activity	49/1068	359/18722	1.24164870345586e-08	2.58684803237368e-07	APOE/SORL1/DUSP1/PYCARD/SLC8A1/CSF1R/ACTB/LYN/RB1/TAOK3/RHOA/SYK/CD300A/CIB1/TLR4/VEGFA/DAZAP2/TGFB1/CSK/IRAK1/PTPN6/ADAM8/SH2B3/IRAK3/LRRK2/PRKAG2/ACSL1/STK4/PTK2B/CDKN1A/ADAM9/PTPRJ/IL1B/TNFAIP3/RGCC/PRKAR1A/CALM3/IQGAP1/CAB39/ADAM17/APC/CEBPA/PAK1/NUP62/AKAP13/TAOK1/RGS2/CCNL1/CCNI	49
GO:0001776	leukocyte homeostasis	21/1068	87/18722	1.28532630897406e-08	2.66754644739385e-07	CD74/TNFSF13B/SKIL/LGALS9/GAPT/HIF1A/MEF2C/NCKAP1L/LYN/GPR183/DOCK10/AXL/CORO1A/TCIRG1/SH2B3/TSC22D3/TNFAIP3/ADAM17/PPP2R3C/BAX/CAMLG	21
GO:0002532	production of molecular mediator involved in inflammatory response	22/1068	95/18722	1.32355285764413e-08	2.73635678921369e-07	TREM2/GRN/ALOX5AP/PYCARD/PLD3/CLEC7A/LILRB4/CD36/HIF1A/LYN/SYK/GPSM3/SIRPA/ALOX5/TLR4/NCF1/BTK/GBP5/MYD88/STAT3/ADCY7/APPL1	22
GO:0045453	bone resorption	18/1068	65/18722	1.37369409545615e-08	2.82918066377153e-07	SPP1/ACP5/HAMP/SNX10/TPP1/CSF1R/PDK4/SYK/P2RX7/TCIRG1/CSK/GPR137B/ADAM8/INPP5D/PTK2B/RAC1/ATP6AP1/TNFAIP3	18
GO:0032609	interferon-gamma production	24/1068	112/18722	1.50129485841992e-08	3.04607409220176e-07	HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-A/LAPTM5/ISG15/CD14/PYCARD/HAVCR2/CLEC7A/IL18/SLC11A1/LGALS9/LILRB4/TLR7/AXL/SIRPA/LILRB1/IRF8/TLR4/PRNP/SASH3/TLR8/IL1B	24
GO:0032649	regulation of interferon-gamma production	24/1068	112/18722	1.50129485841992e-08	3.04607409220176e-07	HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-A/LAPTM5/ISG15/CD14/PYCARD/HAVCR2/CLEC7A/IL18/SLC11A1/LGALS9/LILRB4/TLR7/AXL/SIRPA/LILRB1/IRF8/TLR4/PRNP/SASH3/TLR8/IL1B	24
GO:0046632	alpha-beta T cell differentiation	24/1068	112/18722	1.50129485841992e-08	3.04607409220176e-07	HLA-DRA/HLA-DRB1/CD86/IL18/CD83/LGALS9/LILRB4/NCKAP1L/GPR183/RHOA/SYK/PTGER4/TGFBR2/RSAD2/PRDM1/RUNX1/SASH3/IL6R/BCL6/SPN/STAT6/STAT3/IRF1/NFKBIZ	24
GO:0007568	aging	47/1068	339/18722	1.50158582009946e-08	3.04607409220176e-07	CD68/B2M/C1QA/TIMP1/HAMP/TSPO/LIMS1/SOD2/FOS/LITAF/SPI1/ID2/CTSC/GRB2/JUN/TIMP2/BCL2A1/UCP2/RETN/YBX1/TNFRSF1B/ZMIZ1/PRNP/KYNU/ABI3/TGFBR2/VASH1/IRAK1/NAMPT/BCL6/INPP5D/LRRK2/GPX4/CDKN1A/ERCC1/SERP1/STAT3/SERPING1/BAZ2B/LRP1/CISD2/ERO1A/ATM/CANX/NUP62/MORC3/PICALM	47
GO:0051258	protein polymerization	43/1068	296/18722	1.54674492363862e-08	3.12593093930861e-07	TMSB4X/CAPG/AIF1/PYCARD/COTL1/GRB2/NCKAP1L/ACTR2/ACTR3/GMFG/RHOA/TMSB10/TWF2/HSPA1A/CORO1A/ARPC3/WAS/PREX1/HCK/MYADM/JAK2/VASP/GPX4/PTK2B/ARHGAP18/ARPC4/ARPC1B/CAPZA2/CAPZA1/CYFIP1/RAC1/RNF135/GSN/PAK1/FLII/ARPC5/HCLS1/BRK1/ARF6/CHMP3/DBNL/CAPZB/PFN1	43
GO:0055094	response to lipoprotein particle	13/1068	34/18722	1.90145045320724e-08	3.82844277817399e-07	APOE/CD68/FCER1G/TREM2/CD9/CD81/ITGB2/CD36/LPL/SYK/TLR4/MYD88/ABCA1	13
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	32/1068	186/18722	1.94743703521527e-08	3.90645733904149e-07	HLA-DRB1/CD74/LGALS1/S100A4/BST2/MTDH/LITAF/HMOX1/CLEC7A/LGALS9/CD36/CD4/FLNA/RHOA/TRIM22/REL/CASP1/TLR4/CARD16/CXXC5/IRAK1/TRIM14/SECTM1/TNFSF10/MYD88/ATP2C1/TRIM38/TNFRSF1A/TAB2/NUP62/AKAP13/LTBR	32
GO:0051402	neuron apoptotic process	38/1068	246/18722	1.99856198160879e-08	3.99416313065224e-07	APOE/TYROBP/GPX1/TREM2/CTSZ/CCL3/GRN/NUPR1/SOD2/LGMN/PPT1/C5AR1/HMOX1/JUN/HIF1A/MEF2C/ARRB2/RB1/RHOA/NR4A2/AXL/NAIP/CORO1A/PRNP/ITGAM/BID/JAK2/NQO2/ADAM8/PTK2B/BTG2/MCL1/LRP1/CEBPB/MAX/CDC42/BAX/XIAP	38
GO:0006801	superoxide metabolic process	19/1068	74/18722	2.13234288065288e-08	4.24580154391252e-07	TYROBP/CYBA/ACP5/ITGB2/SOD2/CYBB/NCF2/CLEC7A/CD36/GNAI2/SYK/PREX1/TGFB1/HVCN1/NCF4/ITGAM/NCF1/CYB5R4/BST1	19
GO:0051051	negative regulation of transport	58/1068	470/18722	2.43607393381806e-08	4.83274078929495e-07	APOE/APOC1/CD74/FABP5/HAMP/BST2/CD84/HMOX1/SPI1/LGALS3/LGALS9/CD36/HLA-F/NCKAP1L/GNAI2/UCP2/PLSCR1/PEA15/SDCBP/TMBIM6/CD300A/TLR2/SIRPA/CORO1A/LILRB1/TNFRSF1B/RAP1A/OAZ1/SP100/MDFIC/LILRB2/RSAD2/CSK/KCNE3/MCTP1/CD300LF/NR1H3/RIN3/RHBDF2/CD33/LRRK2/PTK2B/SLC30A1/IL1B/CYFIP1/RAC1/CALM3/TNFRSF1A/CAB39/GSTO1/ATG3/PICALM/ARF6/RGS2/WNK1/APPL1/RAB7A/PPIF	58
GO:0044403	biological process involved in symbiotic interaction	42/1068	290/18722	2.48338312829644e-08	4.90854775102109e-07	APOE/HLA-DRB1/CD74/LGALS1/CTSB/GPX1/CD81/IFI27/CCL3/CXCR4/CD86/IFITM3/LGALS9/JUN/CD4/PLSCR1/CCL4/TRIM22/CLEC5A/AXL/HSPA1A/IFIT1/TNFRSF14/ANPEP/CIITA/TREM1/SIGLEC1/SELPLG/SAP30/TRIM14/ITGA5/MYD88/SCARB2/TRIM38/KPNA3/IGF2R/ARL8B/GSN/CFL1/LAMP1/CHMP3/RAB7A	42
GO:2000403	positive regulation of lymphocyte migration	13/1068	35/18722	2.86748065071694e-08	5.64705313549949e-07	AIF1/CCL3/PYCARD/CCL4/RHOA/TNFRSF14/ADAM8/ITGA4/SPN/PTK2B/ADAM17/ADAM10/WNK1	13
GO:0072593	reactive oxygen species metabolic process	37/1068	239/18722	2.88751405642116e-08	5.66582758125403e-07	TYROBP/GPX1/CYBA/ACP5/TSPO/ITGB2/SOD2/CYBB/NCF2/CLEC7A/GRB2/CD36/HIF1A/GNAI2/PDK4/RHOA/SYK/ALOX5/TLR4/PREX1/TGFB1/DDIT4/TGFBR2/HVCN1/NCF4/ITGAM/NCF1/NQO2/CYB5R4/LRRK2/PTK2B/CDKN1A/PRCP/STAT3/RAC1/BST1/DHRS4	37
GO:0031341	regulation of cell killing	22/1068	99/18722	2.95860092046483e-08	5.78427919087979e-07	HLA-DRA/HLA-DRB1/TYROBP/HLA-A/HLA-B/B2M/HLA-E/SPI1/HAVCR2/CLEC7A/LGALS9/HLA-F/NCKAP1L/PTPRC/ARRB2/SYK/LILRB1/P2RX7/ITGAM/MR1/LAMP1/STX7	22
GO:0045582	positive regulation of T cell differentiation	21/1068	91/18722	3.01165832515036e-08	5.86675390704381e-07	HLA-DRA/HLA-DRB1/CD74/CD86/IL18/CD83/LGALS9/LILRB4/NCKAP1L/PTPRC/RHOA/SYK/IL4I1/ZMIZ1/TGFBR2/LILRB2/RUNX1/ADAM8/SASH3/BCL6/NFKBIZ	21
GO:0030865	cortical cytoskeleton organization	17/1068	61/18722	3.12136981115299e-08	6.05652918616364e-07	PLEK/LCP1/NCKAP1L/RHOA/RHOQ/RHOG/FMNL1/FMNL3/TLN1/RAC1/ROCK1/RHOB/PPP2R3C/ARF6/FMNL2/PLEC/RAB13	17
GO:0070482	response to oxygen levels	47/1068	347/18722	3.1315263953663e-08	6.05652918616364e-07	CYBA/TREM2/CXCR4/SOD2/HMOX1/SLC8A1/CYBB/HIF1A/ZFP36L1/UCP2/RHOA/ATP6V0D1/TMBIM6/TLR2/NR4A2/EIF4EBP1/CASP1/VEGFA/CARD16/DDIT4/TGFBR2/ATP6V1A/ACAA2/PLAU/IRAK1/ADAM8/PLK3/CYB5R4/NAMPT/ATP1B1/MMP2/AGTRAP/BNIP3L/PTK2B/CDKN1A/MALAT1/ATP6AP1/RGCC/LDHA/ERO1A/VEGFB/PGK1/GNB1/ADAM17/BACH1/PAK1/EGR1	47
GO:2000379	positive regulation of reactive oxygen species metabolic process	19/1068	76/18722	3.41518777661997e-08	6.58155472951476e-07	TYROBP/CYBA/TSPO/ITGB2/SOD2/CLEC7A/GRB2/CD36/GNAI2/SYK/TLR4/TGFB1/TGFBR2/HVCN1/ITGAM/NQO2/PTK2B/CDKN1A/DHRS4	19
GO:0001667	ameboidal-type cell migration	58/1068	475/18722	3.55408808464431e-08	6.82486096254117e-07	APOE/TMSB4X/GPX1/TIMP1/GRN/GLUL/CTSH/ZEB2/LGMN/HMOX1/SLC8A1/ARHGDIB/HIF1A/MEF2C/RHOA/CORO1C/CIB1/HBEGF/KLF4/GLIPR2/VEGFA/SP100/PLXND1/TNFSF12/TGFB1/TGFBR2/VASH1/RIN2/LPXN/STAT5A/ITGA4/SPRED1/ARHGAP4/RRAS/PTK2B/CAP1/ADAM9/PRKX/PRCP/SGPL1/RAC1/RGCC/TGFBR1/RTN4/ROCK1/ADAM17/PAK1/SVBP/RHOB/NR4A1/LAMTOR2/ARF6/RCC2/APPL1/ZFAND5/PLEC/PFN1/RAB13	58
GO:0002702	positive regulation of production of molecular mediator of immune response	24/1068	117/18722	3.68028605414068e-08	7.04213600997982e-07	CD74/HLA-A/LAPTM5/B2M/CD81/HLA-E/CD86/CLEC7A/IL18/CD36/HLA-F/PTPRC/LILRB1/TNFRSF14/TLR4/TGFB1/SCIMP/RSAD2/SASH3/DENND1B/STAT6/LACC1/IL1B/STX4	24
GO:0046718	viral entry into host cell	27/1068	144/18722	3.908043787111e-08	7.45152094531836e-07	HLA-DRB1/CD74/LGALS1/CTSB/CD81/CXCR4/CD86/IFITM3/LGALS9/CD4/PLSCR1/TRIM22/CLEC5A/AXL/HSPA1A/TNFRSF14/ANPEP/CIITA/SIGLEC1/SELPLG/TRIM14/ITGA5/SCARB2/TRIM38/KPNA3/GSN/LAMP1	27
GO:0002260	lymphocyte homeostasis	17/1068	62/18722	4.07380292164635e-08	7.68609809972158e-07	CD74/TNFSF13B/SKIL/LGALS9/GAPT/HIF1A/MEF2C/NCKAP1L/LYN/DOCK10/CORO1A/TCIRG1/TSC22D3/TNFAIP3/PPP2R3C/BAX/CAMLG	17
GO:0032623	interleukin-2 production	17/1068	62/18722	4.07380292164635e-08	7.68609809972158e-07	LAPTM5/ZFP36/CD86/HAVCR2/CLEC7A/CD83/LILRB4/PTPRC/GBP1/CD4/HOMER3/PRNP/RUNX1/VSIG4/SASH3/IL1B/TNFAIP3	17
GO:0032663	regulation of interleukin-2 production	17/1068	62/18722	4.07380292164635e-08	7.68609809972158e-07	LAPTM5/ZFP36/CD86/HAVCR2/CLEC7A/CD83/LILRB4/PTPRC/GBP1/CD4/HOMER3/PRNP/RUNX1/VSIG4/SASH3/IL1B/TNFAIP3	17
GO:0034612	response to tumor necrosis factor	38/1068	253/18722	4.30699448835907e-08	8.09774991609253e-07	TMSB4X/LAPTM5/CYBA/CCL3/CCL3L3/HAMP/ASAH1/LIMS1/CXCL16/CD14/ZFP36L2/TNFSF13B/PYCARD/STAT1/ZFP36/ZFP36L1/GBP1/CCL4/SYK/CIB1/HSPA1A/TNFRSF1B/TNFRSF14/CASP1/GBP2/CARD16/CD58/JAK2/KLF2/ARHGEF2/PTK2B/ADAM9/TNFAIP3/NFKBIA/TNFRSF1A/ADAM17/CEBPA/ADAM10	38
GO:0008360	regulation of cell shape	28/1068	154/18722	4.39353172630896e-08	8.23176985943165e-07	CCL3/ITGB2/LST1/CSF1R/MSN/PLEKHO1/PLXNC1/RHOA/CORO1A/RHOQ/RHOG/FMNL1/VEGFA/PLXND1/HCK/FGD4/FMNL3/ARHGAP15/FGR/PTK2B/ARHGAP18/ARAP1/CYFIP1/RAC1/SH3KBP1/RHOB/ARHGDIA/FMNL2	28
GO:0031589	cell-substrate adhesion	48/1068	363/18722	4.77920595445792e-08	8.92338938763147e-07	LGALS1/ITGB2/LIMS1/CD44/CD63/CD36/GBP1/FLNA/RHOA/FERMT3/CORO1C/CIB1/AXL/CORO1A/PARVG/ZYX/VEGFA/PREX1/OTOA/HPSE/SIGLEC1/PLAU/MYADM/PLEKHA2/JAK2/RIN2/LPXN/ITGA4/MYO1G/BCL6/ITGAL/ITGA5/RRAS/STK4/PTK2B/ADAM9/PTPRJ/PRKX/RAC1/LRP1/BST1/DUSP3/IQGAP1/ROCK1/CDC42/RCC2/PIK3R1/S100A10	48
GO:0001913	T cell mediated cytotoxicity	15/1068	49/18722	5.03763335588055e-08	9.37347227183843e-07	HLA-DRA/HLA-DRB1/HLA-A/HLA-B/B2M/CTSH/HLA-E/CTSC/HLA-F/NCKAP1L/PTPRC/LILRB1/MR1/HPRT1/STX7	15
GO:0032677	regulation of interleukin-8 production	22/1068	102/18722	5.24809191154998e-08	9.731513386503e-07	CD74/TMSB4X/CD14/PYCARD/CLEC7A/LGALS9/PTPRC/TLR7/SYK/TLR2/HSPA1A/TLR4/KLF4/TLR1/CD58/TLR5/TLR8/LILRA2/CD33/MYD88/IL1B/STAT3	22
GO:0002711	positive regulation of T cell mediated immunity	16/1068	56/18722	5.38444445941333e-08	9.91619873822333e-07	HLA-DRA/HLA-DRB1/HLA-A/HLA-B/B2M/CD81/HLA-E/IL18/HLA-F/PTPRC/RSAD2/SASH3/DENND1B/MR1/IL1B/STX7	16
GO:0045071	negative regulation of viral genome replication	16/1068	56/18722	5.38444445941333e-08	9.91619873822333e-07	BST2/ISG15/IFI16/MX1/IFITM3/PLSCR1/OAS1/IFIT1/OAS2/RSAD2/OAS3/APOBEC3C/APOBEC3A/IFIH1/EIF2AK2/FAM111A	16
GO:0001782	B cell homeostasis	12/1068	31/18722	5.73456519221648e-08	1.05250727133334e-06	CD74/TNFSF13B/GAPT/HIF1A/MEF2C/NCKAP1L/LYN/DOCK10/TNFAIP3/PPP2R3C/BAX/CAMLG	12
GO:0052126	movement in host environment	30/1068	175/18722	5.83766521853282e-08	1.0677980176001e-06	HLA-DRB1/CD74/LGALS1/CTSB/CD81/CXCR4/CD86/IFITM3/LGALS9/CD4/PLSCR1/TRIM22/CLEC5A/AXL/HSPA1A/TNFRSF14/ANPEP/CIITA/SIGLEC1/SELPLG/TRIM14/ITGA5/SCARB2/TRIM38/KPNA3/ARL8B/GSN/LAMP1/CHMP3/RAB7A	30
GO:0045730	respiratory burst	13/1068	37/18722	6.21764373374285e-08	1.1334596482188e-06	CYBA/TREM2/GRN/CYBB/NCF2/CLEC7A/SLC11A1/CD52/HCK/NCF4/NCF1/CAMK1D/RAC1	13
GO:0032637	interleukin-8 production	22/1068	103/18722	6.31869210706834e-08	1.14800210807208e-06	CD74/TMSB4X/CD14/PYCARD/CLEC7A/LGALS9/PTPRC/TLR7/SYK/TLR2/HSPA1A/TLR4/KLF4/TLR1/CD58/TLR5/TLR8/LILRA2/CD33/MYD88/IL1B/STAT3	22
GO:0051495	positive regulation of cytoskeleton organization	35/1068	226/18722	6.74297827493919e-08	1.22097687152926e-06	GPR65/PLEK/PYCARD/CCDC88A/GRB2/NCKAP1L/ACTR2/ACTR3/FLNA/GMFG/RHOA/HSPA1A/CORO1A/ARPC3/P2RX7/WAS/HCK/VASP/PTK2B/ARPC4/ARPC1B/CYFIP1/RAC1/RGCC/TGFBR1/GSN/PAK1/NUP62/ARPC5/HCLS1/BRK1/ARF6/CDC42/PFN1/S100A10	35
GO:0009612	response to mechanical stimulus	34/1068	216/18722	6.90777240061744e-08	1.24652296381495e-06	CYBA/TXNIP/CXCR4/FOS/STAT1/SLC8A1/MAP3K2/JUN/RETN/RHOA/TLR7/PTGER4/CASP1/TLR4/ENG/TGFBR2/TLR5/TLR8/MYD88/PTK2B/BTG2/IL1B/RAC1/ABHD12/NFKBIA/FOSB/IRF1/TNFRSF1A/GSN/SLC1A3/LTBR/ARHGDIA/ATP1A1/PLEC	34
GO:0150146	cell junction disassembly	10/1068	21/18722	6.93026110349304e-08	1.24652296381495e-06	C1QB/TREM2/C3/C1QA/C1QC/ITGAM/DUSP3/TGFBR1/ARF6/PIK3R1	10
GO:0032729	positive regulation of interferon-gamma production	18/1068	72/18722	7.81378451164557e-08	1.40077014036012e-06	HLA-DPA1/HLA-DPB1/HLA-A/ISG15/CD14/PYCARD/HAVCR2/CLEC7A/IL18/SLC11A1/LGALS9/TLR7/LILRB1/IRF8/TLR4/SASH3/TLR8/IL1B	18
GO:0042554	superoxide anion generation	14/1068	44/18722	8.14723949030057e-08	1.45090773233208e-06	TYROBP/CYBA/ACP5/ITGB2/CYBB/NCF2/CLEC7A/GNAI2/SYK/TGFB1/HVCN1/NCF4/ITGAM/NCF1	14
GO:0062208	positive regulation of pattern recognition receptor signaling pathway	14/1068	44/18722	8.14723949030057e-08	1.45090773233208e-06	CYBA/SLC15A3/TLR2/HSPA1A/TLR4/TLR1/RSAD2/IFI35/TLR5/NR1H3/NINJ1/RTN4/PJA2/FLOT1	14
GO:0009595	detection of biotic stimulus	13/1068	38/18722	8.95900131135477e-08	1.58500888774001e-06	HLA-DRB1/HLA-A/HLA-B/TREM2/LY96/TSPO/CLEC7A/TLR2/NAIP/TLR4/TLR1/PTPRJ/PAK1	13
GO:0097242	amyloid-beta clearance	13/1068	38/18722	8.95900131135477e-08	1.58500888774001e-06	APOE/MSR1/TREM2/C3/ITGB2/C5AR1/CD36/IFNGR1/MARCO/ITGAM/LRP1/ROCK1/PICALM	13
GO:1901216	positive regulation of neuron death	21/1068	97/18722	9.81260980693295e-08	1.73035433066046e-06	TYROBP/CTSZ/C1QA/CCL3/GRN/NUPR1/ITGB2/FOS/JUN/RHOA/TLR4/PRNP/DDIT4/ITGAM/NQO2/TRPM2/MCL1/PICALM/CDC42/BAX/EGR1	21
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	9/1068	17/18722	9.92242896133172e-08	1.74402041287772e-06	HLA-A/HLA-B/HLA-C/B2M/HLA-E/HLA-F/TAPBP/TAP1/ERAP2	9
GO:0044409	entry into host	27/1068	151/18722	1.09022968550192e-07	1.91002577369103e-06	HLA-DRB1/CD74/LGALS1/CTSB/CD81/CXCR4/CD86/IFITM3/LGALS9/CD4/PLSCR1/TRIM22/CLEC5A/AXL/HSPA1A/TNFRSF14/ANPEP/CIITA/SIGLEC1/SELPLG/TRIM14/ITGA5/SCARB2/TRIM38/KPNA3/GSN/LAMP1	27
GO:0060333	interferon-gamma-mediated signaling pathway	11/1068	27/18722	1.10652403200647e-07	1.93229892450063e-06	STAT1/IFNGR2/IFNGR1/JAK1/PARP9/SP100/HCK/JAK2/NR1H3/PARP14/IRF1	11
GO:0072678	T cell migration	17/1068	66/18722	1.1159110251042e-07	1.94240512627815e-06	AIF1/CCL3/CXCL16/PYCARD/MSN/GPR183/RHOA/TNFRSF14/ADAM8/ITGA4/MYO1G/SPN/ITGAL/ADAM17/ADAM10/WNK1/PLEC	17
GO:0001910	regulation of leukocyte mediated cytotoxicity	19/1068	82/18722	1.27011100319379e-07	2.18922361932632e-06	HLA-DRA/HLA-DRB1/TYROBP/HLA-A/HLA-B/B2M/HLA-E/SPI1/HAVCR2/LGALS9/HLA-F/NCKAP1L/PTPRC/ARRB2/LILRB1/ITGAM/MR1/LAMP1/STX7	19
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	19/1068	82/18722	1.27011100319379e-07	2.18922361932632e-06	GPX1/HMOX1/SPI1/LGALS3/SKIL/HGF/PEA15/SP100/BID/STK4/ARHGEF2/GABARAP/TNFAIP3/STX4/BLOC1S2/TNFRSF1A/BAX/ATF3/PIK3R1	19
GO:0002347	response to tumor cell	13/1068	39/18722	1.27393665023807e-07	2.18922361932632e-06	HLA-DRB1/HLA-A/LAPTM5/TXNIP/SPI1/HAVCR2/HNMT/IL4I1/AHR/KLF4/ABI3/MR1/DAPK1	13
GO:0032728	positive regulation of interferon-beta production	13/1068	39/18722	1.27393665023807e-07	2.18922361932632e-06	ISG15/TLR7/TLR2/OAS1/OAS2/TLR4/IRF7/OAS3/TLR8/IFIH1/RNF135/IRF1/FLOT1	13
GO:0000302	response to reactive oxygen species	34/1068	222/18722	1.36239897541591e-07	2.33381107026802e-06	APOE/GPX1/TXNIP/SOD2/FOS/DUSP1/STAT1/HMOX1/SLC8A1/JUN/CD36/HIF1A/HGF/UCP2/AXL/SIRPA/KLF4/NCF1/BTK/KLF2/PLK3/TRPM2/MMP2/LRRK2/PTK2B/STAT6/ADAM9/TNFAIP3/LDHA/SESN3/SETX/RHOB/UBE3A/PPIF	34
GO:0043523	regulation of neuron apoptotic process	33/1068	212/18722	1.4057737752348e-07	2.40049218074905e-06	APOE/TYROBP/TREM2/CTSZ/CCL3/GRN/NUPR1/SOD2/LGMN/PPT1/C5AR1/HMOX1/JUN/HIF1A/MEF2C/ARRB2/RHOA/NR4A2/AXL/NAIP/CORO1A/PRNP/ITGAM/JAK2/NQO2/ADAM8/PTK2B/BTG2/MCL1/LRP1/CEBPB/CDC42/BAX	33
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	21/1068	99/18722	1.42132985315613e-07	2.41179115963223e-06	CD74/NUPR1/CD44/PYCARD/IFI16/HMOX1/SKIL/BCL2A1/TNFRSF1B/DDIT4/CRIP1/BID/FNIP2/CDKN1A/MCL1/RPS27L/ATM/TNFRSF1A/ZNF385A/BAX/PIK3R1	21
GO:0030838	positive regulation of actin filament polymerization	21/1068	99/18722	1.42132985315613e-07	2.41179115963223e-06	PYCARD/GRB2/NCKAP1L/ACTR2/ACTR3/GMFG/RHOA/CORO1A/ARPC3/WAS/HCK/VASP/PTK2B/ARPC4/ARPC1B/CYFIP1/GSN/ARPC5/BRK1/ARF6/PFN1	21
GO:0050920	regulation of chemotaxis	34/1068	223/18722	1.52130349404657e-07	2.57333970340918e-06	CD74/TMSB4X/TREM2/AIF1/CCL3/CXCR4/LGMN/DUSP1/C5AR1/SPI1/CSF1R/C3AR1/LGALS9/PLA2G7/NCKAP1L/LYN/GPR183/CCL4/GPSM3/VEGFA/CCR1/TGFB1/CAMK1D/RIN3/IL6R/PTK2B/RAC1/BST1/VEGFB/STX4/DUSP3/ADAM17/ADAM10/WNK1	34
GO:0002707	negative regulation of lymphocyte mediated immunity	15/1068	53/18722	1.61128936536709e-07	2.71703669235026e-06	HLA-A/HLA-B/HLA-E/HAVCR2/LGALS9/LILRB4/HLA-F/NCKAP1L/PTPRC/ARRB2/IL4I1/LILRB1/AHR/PTPN6/BCL6	15
GO:0034123	positive regulation of toll-like receptor signaling pathway	11/1068	28/18722	1.72867019113992e-07	2.89686470540094e-06	CYBA/TLR2/TLR1/RSAD2/IFI35/TLR5/NR1H3/NINJ1/RTN4/PJA2/FLOT1	11
GO:0038094	Fc-gamma receptor signaling pathway	11/1068	28/18722	1.72867019113992e-07	2.89686470540094e-06	FCER1G/PTPRC/LYN/SYK/RAP1A/HCK/MYO1G/FGR/PTPRJ/PAK1/APPL1	11
GO:2000116	regulation of cysteine-type endopeptidase activity	35/1068	235/18722	1.80162636390922e-07	2.99967720834938e-06	CTSD/LAPTM5/GPX1/PLAUR/CTSH/CD44/LGMN/PYCARD/IFI16/PSMB9/CLEC7A/LGALS9/ARRB2/HGF/RHOA/SYK/NAIP/CASP1/KLF4/VEGFA/CARD16/BID/JAK2/RPS6KA1/TNFSF10/RPS27L/DAPK1/RPS6KA3/PAK2/GSN/NR4A1/FNIP1/HERPUD1/BAX/XIAP	35
GO:0051346	negative regulation of hydrolase activity	48/1068	379/18722	1.80638202777298e-07	2.99967720834938e-06	APOC1/GPX1/GCHFR/C3/CSTB/TIMP1/CST3/PLAUR/BST2/CD44/SORL1/IFI16/SERPINA1/LGALS3/A2M/TIMP2/NCKAP1L/ARRB2/GNAI2/HGF/TMBIM6/NAIP/KLF4/PRNP/VEGFA/CARD16/RPS6KA1/LRRK2/CSTA/SERPINB8/SERPING1/LRP1/RPS6KA3/PAK2/ROCK1/PPP1R15A/OXA1L/NR4A1/TMED10/PICALM/FNIP1/HERPUD1/RGS2/XIAP/RCC2/WNK1/BOD1L1/PPIF	48
GO:2001233	regulation of apoptotic signaling pathway	46/1068	356/18722	1.80669957878715e-07	2.99967720834938e-06	CD74/GPX1/TREM2/NUPR1/PLAUR/CTSH/CD44/SOD2/PYCARD/HMOX1/LGALS3/CTSC/SKIL/HIF1A/PTPRC/ARRB2/GNAI2/RB1/HGF/PEA15/TMBIM6/NR4A2/HSPA1A/SP100/TNFSF12/ACAA2/BID/LRRK2/TNFSF10/STK4/ARHGEF2/SLC35F6/MCL1/IL1B/TNFAIP3/GRINA/STX4/TGFBR1/PAK2/IVNS1ABP/ZNF385A/HERPUD1/BAX/LTBR/ATF3/PPIF	46
GO:0034134	toll-like receptor 2 signaling pathway	9/1068	18/18722	1.88382298394684e-07	3.11813154029974e-06	CYBA/TREM2/LYN/TLR2/TLR1/PIK3AP1/IRAK1/TNFAIP3/PJA2	9
GO:0050869	negative regulation of B cell activation	12/1068	34/18722	1.89972575848938e-07	3.13483797945221e-06	TYROBP/LAPTM5/ID2/LYN/SAMSN1/MNDA/CD300A/BTK/BCL6/INPP5D/TNFAIP3/ATM	12
GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	7/1068	10/18722	1.98796669266726e-07	3.27044764440017e-06	PTPRC/LYN/PLSCR1/RAP1A/CSK/PTPRJ/APPL1	7
GO:0034113	heterotypic cell-cell adhesion	16/1068	61/18722	2.0016193266397e-07	3.27295087471146e-06	ITGB2/CD44/PTPRC/ITGAX/SIRPA/MBP/KLF4/CD58/LILRB2/MYADM/ITGA4/ITGA5/IL1B/NINJ1/WNK1/FLOT1	16
GO:0043030	regulation of macrophage activation	16/1068	61/18722	2.0016193266397e-07	3.27295087471146e-06	CD74/TREM2/CCL3/GRN/HAMP/CD84/HAVCR2/CTSC/PTPRC/TLR4/GPR137B/VSIG4/NR1H3/LRRK2/CEBPA/PJA2	16
GO:0042102	positive regulation of T cell proliferation	21/1068	101/18722	2.03678610641681e-07	3.32039209372359e-06	HLA-DPA1/HLA-DPB1/HLA-A/AIF1/CD81/HLA-DMB/HLA-E/TNFSF13B/PYCARD/CD86/HAVCR2/IL18/LGALS9/NCKAP1L/PTPRC/SYK/CORO1A/TGFBR2/LILRB2/SASH3/IL1B	21
GO:0045646	regulation of erythrocyte differentiation	14/1068	47/18722	2.06146595675091e-07	3.35050310320118e-06	B2M/MAFB/ISG15/STAT1/ZFP36/SPI1/HIF1A/ZFP36L1/NCKAP1L/LYN/HSPA1A/INPP5D/STAT3/SMAP1	14
GO:0031098	stress-activated protein kinase signaling cascade	36/1068	247/18722	2.08945674552227e-07	3.38579837802947e-06	TREM2/DUSP1/PYCARD/ZFP36/SPI1/CLEC7A/GADD45B/LGALS9/ZFP36L1/LYN/HGF/SDCBP/TAOK3/RHOA/TLR7/SIRPA/PTGER4/RNF13/TLR4/VEGFA/MDFIC/SCIMP/NCF1/IRAK1/RASSF2/LRRK2/MYD88/RAP2A/PTK2B/IL1B/EIF2AK2/DUSP3/PJA2/CDC42/TAOK1/LTBR	36
GO:1901224	positive regulation of NIK/NF-kappaB signaling	17/1068	69/18722	2.24917228768158e-07	3.6336927138712e-06	LAPTM5/TREM2/LIMS1/CD14/CD86/HAVCR2/IL18/LGALS9/RHOA/TLR7/TLR2/TLR4/IFI35/IRAK1/C20orf27/IL1B/EIF2AK2	17
GO:0045069	regulation of viral genome replication	19/1068	85/18722	2.32909901132154e-07	3.75158754181822e-06	BST2/ISG15/IFI16/MX1/IFITM3/PLSCR1/OAS1/IFIT1/OAS2/PABPC1/RSAD2/OAS3/APOBEC3C/APOBEC3A/IFIH1/EIF2AK2/ADAR/DDX5/FAM111A	19
GO:1901342	regulation of vasculature development	45/1068	348/18722	2.4011389354517e-07	3.85611479038612e-06	GPNMB/C3/GRN/GLUL/CXCR4/CTSH/MTDH/C5AR1/STAT1/HMOX1/CYBB/C3AR1/HIF1A/HGF/ITGAX/ALOX5/JAK1/KLF4/VEGFA/SP100/PLXND1/TNFSF12/ENG/TGFBR2/VASH1/STAB1/RUNX1/KLF2/SPRED1/ITGA5/RRAS/PTK2B/IL1B/STAT3/TNFAIP3/RGCC/NINJ1/BTG1/VEGFB/PGK1/ROCK1/RHOB/PKM/ADAM10/RNH1	45
GO:0035710	CD4-positive, alpha-beta T cell activation	21/1068	102/18722	2.42878012148471e-07	3.88893101944554e-06	HLA-DRA/HLA-DRB1/CD81/CD86/IL18/CD83/LGALS9/NCKAP1L/GPR183/PTGER4/TGFBR2/TCIRG1/RSAD2/RUNX1/SASH3/IL6R/BCL6/SPN/STAT6/STAT3/NFKBIZ	21
GO:0070374	positive regulation of ERK1 and ERK2 cascade	33/1068	217/18722	2.45569757183572e-07	3.9203976620194e-06	APOE/HLA-DRB1/CD74/GPNMB/TREM2/CCL3/CCL3L3/CD44/PYCARD/C5AR1/HAVCR2/CSF1R/LGALS9/CD36/PTPRC/ARRB2/GNAI2/GPR183/CD4/CCL4/MARCO/CIB1/RAP1A/TLR4/GLIPR2/CCR1/TGFB1/SCIMP/NQO2/NOTCH2/PTK2B/ATP6AP1/LRP1	33
GO:2000377	regulation of reactive oxygen species metabolic process	27/1068	157/18722	2.48371040171262e-07	3.95342222054316e-06	TYROBP/CYBA/ACP5/TSPO/ITGB2/SOD2/CLEC7A/GRB2/CD36/HIF1A/GNAI2/RHOA/SYK/ALOX5/TLR4/TGFB1/TGFBR2/HVCN1/ITGAM/NQO2/PTK2B/CDKN1A/PRCP/STAT3/RAC1/BST1/DHRS4	27
GO:0032613	interleukin-10 production	16/1068	62/18722	2.55613725167449e-07	4.02125848689083e-06	HLA-DRB1/TYROBP/TREM2/ISG15/PYCARD/CLEC7A/CD83/LGALS9/LILRB4/HGF/SYK/TLR2/LILRB1/TLR4/SASH3/STAT3	16
GO:0032615	interleukin-12 production	16/1068	62/18722	2.55613725167449e-07	4.02125848689083e-06	HLA-B/LAPTM5/ACP5/CLEC7A/LGALS9/CD36/ARRB2/SYK/TLR2/LILRB1/IRF8/TLR4/SCIMP/TLR8/IRAK3/IRF1	16
GO:0032653	regulation of interleukin-10 production	16/1068	62/18722	2.55613725167449e-07	4.02125848689083e-06	HLA-DRB1/TYROBP/TREM2/ISG15/PYCARD/CLEC7A/CD83/LGALS9/LILRB4/HGF/SYK/TLR2/LILRB1/TLR4/SASH3/STAT3	16
GO:0032655	regulation of interleukin-12 production	16/1068	62/18722	2.55613725167449e-07	4.02125848689083e-06	HLA-B/LAPTM5/ACP5/CLEC7A/LGALS9/CD36/ARRB2/SYK/TLR2/LILRB1/IRF8/TLR4/SCIMP/TLR8/IRAK3/IRF1	16
GO:0030004	cellular monovalent inorganic cation homeostasis	21/1068	103/18722	2.88896462302536e-07	4.53164334472234e-06	GRN/PPT1/SLC8A1/SLC11A1/ATP6V0D1/ATP6AP2/SLC4A7/DMXL2/TCIRG1/HVCN1/ATP1B1/LRRK2/LACC1/ATP6V0A1/ATP6AP1/ATP6V0E1/SLC1A3/UBE3A/ATP1B3/ATP1A1/RAB7A	21
GO:0071356	cellular response to tumor necrosis factor	34/1068	229/18722	2.90068719966258e-07	4.53684293605197e-06	TMSB4X/LAPTM5/CYBA/CCL3/CCL3L3/HAMP/ASAH1/LIMS1/ZFP36L2/TNFSF13B/PYCARD/STAT1/ZFP36/ZFP36L1/GBP1/CCL4/SYK/CIB1/HSPA1A/TNFRSF1B/TNFRSF14/CASP1/GBP2/CARD16/CD58/JAK2/KLF2/ARHGEF2/PTK2B/TNFAIP3/NFKBIA/TNFRSF1A/ADAM17/CEBPA	34
GO:1901222	regulation of NIK/NF-kappaB signaling	22/1068	112/18722	3.0073391999111e-07	4.69005847477465e-06	TMSB4X/LAPTM5/TREM2/LIMS1/CD14/LITAF/CD86/SPI1/HAVCR2/IL18/LGALS9/RHOA/TLR7/TLR2/TLR4/IFI35/IRAK1/RASSF2/C20orf27/IL1B/EIF2AK2/NFKBIA	22
GO:0010506	regulation of autophagy	42/1068	317/18722	3.10584871716118e-07	4.82972901377572e-06	PSAP/TREM2/NUPR1/TSPO/MTDH/PYCARD/IFI16/HMOX1/ATP6V0B/HIF1A/HGF/CTSA/ATP6V1B2/ATP6V0D1/TRIM22/IL10RA/CASP1/DRAM2/VPS13C/ATP6V1A/RRAGD/BID/GPR137B/PLK3/NAMPT/TRIM14/LRRK2/BNIP3L/TRIM38/ATP6V0A1/MCL1/STAT3/CAPNS1/DAPK1/CISD2/SESN3/ATM/ROCK1/TAB2/ATP6V0E1/RAB8A/DRAM1	42
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	32/1068	209/18722	3.18130043397463e-07	4.93284400624341e-06	CTSD/LAPTM5/GPX1/PLAUR/CTSH/CD44/PYCARD/CLEC7A/LGALS9/ARRB2/HGF/RHOA/SYK/NAIP/CASP1/KLF4/VEGFA/CARD16/BID/JAK2/RPS6KA1/TNFSF10/RPS27L/DAPK1/RPS6KA3/PAK2/GSN/NR4A1/FNIP1/HERPUD1/BAX/XIAP	32
GO:0031343	positive regulation of cell killing	16/1068	63/18722	3.24638947019722e-07	5.01934601180064e-06	HLA-DRA/HLA-DRB1/TYROBP/HLA-A/HLA-B/B2M/HLA-E/SPI1/CLEC7A/HLA-F/PTPRC/SYK/ITGAM/MR1/LAMP1/STX7	16
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	10/1068	24/18722	3.29203599703892e-07	5.06091915670143e-06	HLA-A/HLA-B/HLA-E/HAVCR2/LGALS9/HLA-F/NCKAP1L/PTPRC/ARRB2/LILRB1	10
GO:0032928	regulation of superoxide anion generation	10/1068	24/18722	3.29203599703892e-07	5.06091915670143e-06	TYROBP/CYBA/ACP5/ITGB2/CLEC7A/GNAI2/SYK/TGFB1/HVCN1/ITGAM	10
GO:0006979	response to oxidative stress	53/1068	446/18722	3.30949627992601e-07	5.07330736547749e-06	APOE/GPX1/TREM2/AIF1/TXNIP/SOD2/FOS/DUSP1/STAT1/HMOX1/SLC8A1/JUN/CD36/HIF1A/HGF/UCP2/NR4A2/AXL/HSPA1A/SIRPA/MGST1/ALOX5/SLC25A24/TLR4/KLF4/PRNP/NCF1/BTK/MCTP1/JAK2/KLF2/PLK3/PTGS1/TRPM2/MMP2/LRRK2/GPX4/PTK2B/STAT6/ERCC1/ADAM9/MCL1/TNFAIP3/DAPK1/BTG1/LDHA/ERO1A/SESN3/STX4/SETX/RHOB/UBE3A/PPIF	53
GO:0002888	positive regulation of myeloid leukocyte mediated immunity	9/1068	19/18722	3.39780262301066e-07	5.19392151664745e-06	TYROBP/C3/HLA-E/ITGB2/SPI1/PTAFR/ITGAM/BTK/STX4	9
GO:0048661	positive regulation of smooth muscle cell proliferation	21/1068	104/18722	3.42792391405306e-07	5.21044434936065e-06	CYBA/AIF1/STAT1/HMOX1/ID2/IL18/JUN/GNAI2/TLR4/HBEGF/TGFB1/TGFBR2/PTAFR/IRAK1/JAK2/NQO2/IL6R/NAMPT/MMP2/MYD88/PAK1	21
GO:1903076	regulation of protein localization to plasma membrane	21/1068	104/18722	3.42792391405306e-07	5.21044434936065e-06	TREM2/LGALS3/ACTB/GBP1/CIB1/RHOQ/RHOG/PRNP/TGFB1/ABI3/CSK/ATP2C1/LRP1/NUMB/STX4/PICALM/ARF6/STX7/APPL1/KIF5B/PIK3R1	21
GO:0045089	positive regulation of innate immune response	24/1068	131/18722	3.4421091056369e-07	5.21730919494852e-06	TYROBP/HLA-E/PYCARD/IFI16/SPI1/HAVCR2/CLEC7A/HLA-F/LYN/MNDA/PLSCR1/SYK/TLR4/PARP9/HCK/IRF7/IFI35/ADAM8/GBP5/TLR8/LILRA2/PAK2/PAK1/LAMP1	24
GO:0001666	response to hypoxia	41/1068	307/18722	3.4593566524985e-07	5.22876428484088e-06	CYBA/TREM2/CXCR4/SOD2/HMOX1/SLC8A1/CYBB/HIF1A/ZFP36L1/UCP2/RHOA/TMBIM6/TLR2/NR4A2/EIF4EBP1/CASP1/VEGFA/CARD16/DDIT4/TGFBR2/ACAA2/PLAU/IRAK1/ADAM8/PLK3/ATP1B1/MMP2/AGTRAP/BNIP3L/PTK2B/MALAT1/RGCC/LDHA/ERO1A/VEGFB/PGK1/GNB1/ADAM17/BACH1/PAK1/EGR1	41
GO:0061515	myeloid cell development	17/1068	71/18722	3.505372227805e-07	5.28351635230049e-06	TYROBP/EVI2B/NCKAP1L/TLR2/LILRB1/PTPN6/NOTCH2/KLF2/SH2B3/BCL6/FLI1/ABI1/ATP6AP1/ARID4A/PABPC4/ZNF385A/PTBP3	17
GO:0002708	positive regulation of lymphocyte mediated immunity	22/1068	113/18722	3.53606365063e-07	5.31493021136475e-06	HLA-DRA/HLA-DRB1/HLA-A/HLA-B/B2M/TREM2/C3/CD81/HLA-E/IL18/HLA-F/PTPRC/TGFB1/RSAD2/BTK/SASH3/DENND1B/STAT6/MR1/IL1B/LAMP1/STX7	22
GO:0031529	ruffle organization	15/1068	56/18722	3.56557043805422e-07	5.34439391215016e-06	AIF1/PLEK/SNX10/CSF1R/CORO1C/RHOG/ABI3/TCIRG1/CYFIP1/RAC1/ARHGAP24/ARF6/RCC2/DBNL/PFN1	15
GO:0045765	regulation of angiogenesis	44/1068	342/18722	3.7645704052815e-07	5.6270420794734e-06	GPNMB/C3/GRN/GLUL/CXCR4/CTSH/MTDH/C5AR1/STAT1/HMOX1/CYBB/C3AR1/HIF1A/HGF/ITGAX/ALOX5/JAK1/KLF4/VEGFA/SP100/PLXND1/TNFSF12/ENG/TGFBR2/VASH1/STAB1/RUNX1/KLF2/SPRED1/ITGA5/RRAS/PTK2B/IL1B/STAT3/TNFAIP3/RGCC/NINJ1/BTG1/VEGFB/PGK1/ROCK1/RHOB/PKM/RNH1	44
GO:0048660	regulation of smooth muscle cell proliferation	29/1068	180/18722	3.79478623836215e-07	5.65653771884038e-06	APOE/CYBA/AIF1/SOD2/STAT1/HMOX1/ID2/IL18/JUN/MEF2C/GNAI2/RHOA/TLR4/HBEGF/KLF4/TGFB1/TGFBR2/PTAFR/IRAK1/JAK2/NQO2/IL6R/NAMPT/MMP2/MYD88/CDKN1A/GNA13/TNFAIP3/PAK1	29
GO:0090322	regulation of superoxide metabolic process	12/1068	36/18722	3.89919234850217e-07	5.76525650531226e-06	TYROBP/CYBA/ACP5/ITGB2/CLEC7A/CD36/GNAI2/SYK/TGFB1/HVCN1/ITGAM/BST1	12
GO:0071214	cellular response to abiotic stimulus	43/1068	331/18722	3.89977506382315e-07	5.76525650531226e-06	CYBA/TIMP1/HAMP/TSPO/IFI16/MAP3K2/GRB2/ZFP36L1/TLR7/PTGER4/CASP1/TLR4/CARD16/ENG/CRIP1/PTAFR/HVCN1/LRRC8C/TLR5/NAMPT/RCSD1/TLR8/MMP2/MYD88/ARHGEF2/CDKN1A/ERCC1/MCOLN1/IL1B/RAC1/ATM/IRF1/TNFRSF1A/CAB39/RHOB/BAX/LTBR/MICU1/ARHGDIA/EGR1/PIK3R1/ATP1A1/PLEC	43
GO:0104004	cellular response to environmental stimulus	43/1068	331/18722	3.89977506382315e-07	5.76525650531226e-06	CYBA/TIMP1/HAMP/TSPO/IFI16/MAP3K2/GRB2/ZFP36L1/TLR7/PTGER4/CASP1/TLR4/CARD16/ENG/CRIP1/PTAFR/HVCN1/LRRC8C/TLR5/NAMPT/RCSD1/TLR8/MMP2/MYD88/ARHGEF2/CDKN1A/ERCC1/MCOLN1/IL1B/RAC1/ATM/IRF1/TNFRSF1A/CAB39/RHOB/BAX/LTBR/MICU1/ARHGDIA/EGR1/PIK3R1/ATP1A1/PLEC	43
GO:0050852	T cell receptor signaling pathway	23/1068	123/18722	4.11575648207754e-07	6.06792950199192e-06	HLA-DRB1/HLA-DPB1/HLA-DQB1/HLA-A/LAPTM5/CD81/LGALS3/LILRB4/PTPRC/GBP1/LCP2/CD300A/PRNP/THEMIS2/CSK/PTPN6/INPP5D/DENND1B/RAB29/PTPRJ/DUSP3/NFKBIZ/WNK1	23
GO:0045766	positive regulation of angiogenesis	29/1068	181/18722	4.27725760413974e-07	6.2717614217223e-06	C3/GRN/CXCR4/CTSH/MTDH/C5AR1/HMOX1/CYBB/C3AR1/HIF1A/HGF/ITGAX/JAK1/KLF4/VEGFA/TNFSF12/ENG/TGFBR2/RUNX1/ITGA5/RRAS/PTK2B/IL1B/STAT3/NINJ1/BTG1/VEGFB/RHOB/PKM	29
GO:1904018	positive regulation of vasculature development	29/1068	181/18722	4.27725760413974e-07	6.2717614217223e-06	C3/GRN/CXCR4/CTSH/MTDH/C5AR1/HMOX1/CYBB/C3AR1/HIF1A/HGF/ITGAX/JAK1/KLF4/VEGFA/TNFSF12/ENG/TGFBR2/RUNX1/ITGA5/RRAS/PTK2B/IL1B/STAT3/NINJ1/BTG1/VEGFB/RHOB/PKM	29
GO:0007160	cell-matrix adhesion	34/1068	233/18722	4.39291011015147e-07	6.42388697950605e-06	ITGB2/LIMS1/CD44/CD63/CD36/RHOA/FERMT3/CORO1C/CIB1/PARVG/ZYX/VEGFA/OTOA/HPSE/SIGLEC1/PLAU/PLEKHA2/RIN2/ITGA4/BCL6/ITGAL/RRAS/PTK2B/ADAM9/PTPRJ/RAC1/LRP1/BST1/DUSP3/IQGAP1/ROCK1/RCC2/PIK3R1/S100A10	34
GO:0006469	negative regulation of protein kinase activity	32/1068	212/18722	4.417703555973e-07	6.4426833481163e-06	APOE/SORL1/DUSP1/PYCARD/SLC8A1/GADD45B/LILRB4/PTPRC/LYN/RB1/CORO1C/CD300A/PTPN6/SH2B3/SPRED1/IRAK3/PRKAG2/CDKN1A/PTPRJ/IL1B/TNFAIP3/ADAR/PRKAR1A/DUSP3/PAK2/APC/CEBPA/NUP62/GNAQ/RGS2/YWHAG/PLEC	32
GO:0097193	intrinsic apoptotic signaling pathway	39/1068	288/18722	4.64990644288939e-07	6.76304451909196e-06	CD74/GPX1/TREM2/NUPR1/PLAUR/CD44/SOD2/PYCARD/IFI16/HMOX1/SKIL/HIF1A/BCL2A1/TMBIM6/HSPA1A/TNFRSF1B/DDIT4/CRIP1/BID/JAK2/LRRK2/ARHGEF2/FNIP2/CDKN1A/MCL1/RPS27L/GRINA/CEBPB/ERO1A/ATM/DDX5/TNFRSF1A/PPP1R15A/IVNS1ABP/ZNF385A/HERPUD1/BAX/PIK3R1/PPIF	39
GO:0036293	response to decreased oxygen levels	42/1068	322/18722	4.76225864494642e-07	6.9078353892825e-06	CYBA/TREM2/CXCR4/SOD2/HMOX1/SLC8A1/CYBB/HIF1A/ZFP36L1/UCP2/RHOA/TMBIM6/TLR2/NR4A2/EIF4EBP1/CASP1/VEGFA/CARD16/DDIT4/TGFBR2/ACAA2/PLAU/IRAK1/ADAM8/PLK3/NAMPT/ATP1B1/MMP2/AGTRAP/BNIP3L/PTK2B/MALAT1/RGCC/LDHA/ERO1A/VEGFB/PGK1/GNB1/ADAM17/BACH1/PAK1/EGR1	42
GO:0001961	positive regulation of cytokine-mediated signaling pathway	14/1068	50/18722	4.81850522563207e-07	6.95204657687451e-06	CD74/LAPTM5/TREM2/CXCR4/HIF1A/AXL/HSPA1A/CASP1/PARP9/AGPAT2/IRF7/CD300LF/PARP14/ADAM17	14
GO:0046638	positive regulation of alpha-beta T cell differentiation	14/1068	50/18722	4.81850522563207e-07	6.95204657687451e-06	HLA-DRA/HLA-DRB1/CD86/IL18/CD83/LGALS9/LILRB4/NCKAP1L/RHOA/SYK/TGFBR2/RUNX1/SASH3/NFKBIZ	14
GO:0010631	epithelial cell migration	45/1068	357/18722	4.98345243365847e-07	7.17085582187229e-06	APOE/TMSB4X/GPX1/GRN/GLUL/CTSH/ZEB2/LGMN/HMOX1/HIF1A/MEF2C/RHOA/CORO1C/CIB1/HBEGF/KLF4/GLIPR2/VEGFA/SP100/PLXND1/TNFSF12/TGFB1/TGFBR2/VASH1/RIN2/LPXN/STAT5A/SPRED1/RRAS/PTK2B/ADAM9/PRKX/PRCP/RAC1/RGCC/TGFBR1/RTN4/ROCK1/ADAM17/SVBP/RHOB/NR4A1/ARF6/PFN1/RAB13	45
GO:0051701	biological process involved in interaction with host	31/1068	203/18722	5.13767044637862e-07	7.37310365123911e-06	HLA-DRB1/CD74/LGALS1/CTSB/CD81/CXCR4/CD86/IFITM3/LGALS9/CD4/PLSCR1/TRIM22/CLEC5A/AXL/HSPA1A/IFIT1/TNFRSF14/ANPEP/CIITA/SIGLEC1/SELPLG/TRIM14/ITGA5/SCARB2/TRIM38/KPNA3/ARL8B/GSN/LAMP1/CHMP3/RAB7A	31
GO:0098581	detection of external biotic stimulus	10/1068	25/18722	5.2063859778356e-07	7.45189886907186e-06	HLA-DRB1/HLA-A/HLA-B/TREM2/LY96/CLEC7A/TLR2/NAIP/TLR4/TLR1	10
GO:0071260	cellular response to mechanical stimulus	18/1068	81/18722	5.28737051506089e-07	7.54779134901284e-06	CYBA/MAP3K2/TLR7/PTGER4/CASP1/TLR4/ENG/TLR5/TLR8/MYD88/IL1B/RAC1/IRF1/TNFRSF1A/LTBR/ARHGDIA/ATP1A1/PLEC	18
GO:1904375	regulation of protein localization to cell periphery	23/1068	125/18722	5.55154049031703e-07	7.90398746325877e-06	TREM2/LGALS3/ACTB/GBP1/CIB1/RHOQ/RAP1A/RHOG/PRNP/TGFB1/ABI3/CSK/ATP2C1/LRP1/NUMB/STX4/ADAM10/PICALM/ARF6/STX7/APPL1/KIF5B/PIK3R1	23
GO:0002577	regulation of antigen processing and presentation	9/1068	20/18722	5.86478885410242e-07	8.2627677954926e-06	CD74/CD68/TREM2/PYCARD/SLC11A1/FGL2/HLA-DOA/WAS/LILRB2	9
GO:0032930	positive regulation of superoxide anion generation	9/1068	20/18722	5.86478885410242e-07	8.2627677954926e-06	TYROBP/CYBA/ITGB2/CLEC7A/GNAI2/SYK/TGFB1/HVCN1/ITGAM	9
GO:0072567	chemokine (C-X-C motif) ligand 2 production	9/1068	20/18722	5.86478885410242e-07	8.2627677954926e-06	CD74/LPL/OAS1/MBP/TLR4/KLF4/OAS3/MYD88/LRP1	9
GO:2000341	regulation of chemokine (C-X-C motif) ligand 2 production	9/1068	20/18722	5.86478885410242e-07	8.2627677954926e-06	CD74/LPL/OAS1/MBP/TLR4/KLF4/OAS3/MYD88/LRP1	9
GO:0048659	smooth muscle cell proliferation	29/1068	184/18722	6.08696498130166e-07	8.55345391643327e-06	APOE/CYBA/AIF1/SOD2/STAT1/HMOX1/ID2/IL18/JUN/MEF2C/GNAI2/RHOA/TLR4/HBEGF/KLF4/TGFB1/TGFBR2/PTAFR/IRAK1/JAK2/NQO2/IL6R/NAMPT/MMP2/MYD88/CDKN1A/GNA13/TNFAIP3/PAK1	29
GO:0090132	epithelium migration	45/1068	360/18722	6.310352803049e-07	8.8443282403253e-06	APOE/TMSB4X/GPX1/GRN/GLUL/CTSH/ZEB2/LGMN/HMOX1/HIF1A/MEF2C/RHOA/CORO1C/CIB1/HBEGF/KLF4/GLIPR2/VEGFA/SP100/PLXND1/TNFSF12/TGFB1/TGFBR2/VASH1/RIN2/LPXN/STAT5A/SPRED1/RRAS/PTK2B/ADAM9/PRKX/PRCP/RAC1/RGCC/TGFBR1/RTN4/ROCK1/ADAM17/SVBP/RHOB/NR4A1/ARF6/PFN1/RAB13	45
GO:0062197	cellular response to chemical stress	43/1068	337/18722	6.3928831124217e-07	8.93678685871178e-06	GPX1/TREM2/AIF1/TSPO/SOD2/FOS/HMOX1/JUN/CD36/HIF1A/ZFP36L1/HGF/NR4A2/AXL/HSPA1A/SIRPA/MGST1/ALOX5/SLC25A24/TLR4/KLF4/LRRC8C/NCF1/BTK/JAK2/KLF2/TRPM2/RCSD1/MMP2/LRRK2/ARHGEF2/STAT6/MCL1/TNFAIP3/DAPK1/ATM/STX4/SETX/CAB39/RHOB/MICU1/PLEC/PPIF	43
GO:0033673	negative regulation of kinase activity	34/1068	237/18722	6.57579485841792e-07	9.16873102222819e-06	APOE/SORL1/DUSP1/PYCARD/SLC8A1/GADD45B/LILRB4/PTPRC/LYN/RB1/CORO1C/CD300A/CSK/PTPN6/SH2B3/SPRED1/IRAK3/PRKAG2/CDKN1A/PTPRJ/IL1B/TNFAIP3/ADAR/PRKAR1A/DUSP3/PAK2/APC/CEBPA/NUP62/GNAQ/RGS2/WNK1/YWHAG/PLEC	34
GO:1905475	regulation of protein localization to membrane	28/1068	175/18722	6.93062219443213e-07	9.63856633019479e-06	TREM2/CD81/ITGB2/LGALS3/ACTB/GBP1/CIB1/RHOQ/RAP1A/RHOG/PRNP/TGFB1/ABI3/CSK/ITGAM/ATP2C1/LRP1/NUMB/STX4/GSN/PAK1/ADAM10/PICALM/ARF6/STX7/APPL1/KIF5B/PIK3R1	28
GO:0046777	protein autophosphorylation	33/1068	227/18722	7.05366798445405e-07	9.78447106532494e-06	GPNMB/CSF1R/RAP2B/PTPRC/LYN/TAOK3/SYK/VEGFA/HCK/ENG/CSK/IRAK1/BTK/JAK2/RASSF2/IRAK3/LRRK2/FGR/MAPKAPK3/STK4/RAP2A/PTK2B/PRKX/EIF2AK2/DAPK1/ATM/CALM3/IQGAP1/PAK2/PAK1/UHMK1/TAOK1/WNK1	33
GO:0045580	regulation of T cell differentiation	25/1068	146/18722	7.4534415398926e-07	1.03125052690411e-05	HLA-DRA/HLA-DRB1/CD74/CD86/IL18/CD83/LGALS9/LILRB4/FGL2/NCKAP1L/PTPRC/RHOA/SYK/IL4I1/HLA-DOA/ZMIZ1/TGFBR2/LILRB2/PRDM1/RUNX1/ADAM8/SASH3/BCL6/IRF1/NFKBIZ	25
GO:0043367	CD4-positive, alpha-beta T cell differentiation	18/1068	83/18722	7.76228843335448e-07	1.07123550860309e-05	HLA-DRA/HLA-DRB1/CD86/IL18/CD83/LGALS9/NCKAP1L/GPR183/PTGER4/RSAD2/RUNX1/SASH3/IL6R/BCL6/SPN/STAT6/STAT3/NFKBIZ	18
GO:0050728	negative regulation of inflammatory response	28/1068	176/18722	7.80174839440097e-07	1.07393454939254e-05	APOE/HLA-DRB1/GPX1/TREM2/ACP5/GRN/HAMP/ZFP36/PTPRC/LYN/RB1/HGF/METRNL/SYK/SIRPA/PTGER4/TNFRSF1B/ALOX5/KLF4/HCK/AOAH/NR1H3/RHBDF2/TNFAIP8L2/FGR/SOCS3/TNFAIP3/TNFRSF1A	28
GO:0042130	negative regulation of T cell proliferation	16/1068	67/18722	8.02565221866208e-07	1.10194451327991e-05	HLA-DRB1/GPNMB/CD86/HAVCR2/LGALS9/LILRB4/IL4I1/LILRB1/TNFRSF14/PRNP/LILRB2/PTPN6/VSIG4/SPN/CEBPB/PRKAR1A	16
GO:0050851	antigen receptor-mediated signaling pathway	34/1068	240/18722	8.83361943090378e-07	1.20980229566388e-05	HLA-DRB1/HLA-DPB1/HLA-DQB1/HLA-A/LAPTM5/CD81/LGALS3/LILRB4/MEF2C/NCKAP1L/PTPRC/GBP1/LYN/MNDA/LCP2/SYK/CMTM3/LAT2/CD300A/PRNP/THEMIS2/CSK/PTPN6/BTK/LPXN/KLHL6/INPP5D/DENND1B/RAB29/PTPRJ/DUSP3/NFKBIZ/BAX/WNK1	34
GO:0032273	positive regulation of protein polymerization	24/1068	138/18722	9.24327757950578e-07	1.26270191946869e-05	PYCARD/GRB2/NCKAP1L/ACTR2/ACTR3/GMFG/RHOA/HSPA1A/CORO1A/ARPC3/WAS/HCK/VASP/PTK2B/ARPC4/ARPC1B/CYFIP1/RAC1/GSN/PAK1/ARPC5/BRK1/ARF6/PFN1	24
GO:0090130	tissue migration	45/1068	365/18722	9.27919853647622e-07	1.26440796219257e-05	APOE/TMSB4X/GPX1/GRN/GLUL/CTSH/ZEB2/LGMN/HMOX1/HIF1A/MEF2C/RHOA/CORO1C/CIB1/HBEGF/KLF4/GLIPR2/VEGFA/SP100/PLXND1/TNFSF12/TGFB1/TGFBR2/VASH1/RIN2/LPXN/STAT5A/SPRED1/RRAS/PTK2B/ADAM9/PRKX/PRCP/RAC1/RGCC/TGFBR1/RTN4/ROCK1/ADAM17/SVBP/RHOB/NR4A1/ARF6/PFN1/RAB13	45
GO:0097530	granulocyte migration	25/1068	148/18722	9.68587718692675e-07	1.31649857180496e-05	CD74/FCER1G/CCL3/CCL3L3/ITGB2/C5AR1/LGALS3/CSF1R/C3AR1/NCKAP1L/CKLF/PECAM1/CCL4/SYK/CD300A/PTGER4/RHOG/PREX1/TREM1/CAMK1D/ADAM8/ADGRE2/MYD88/RAC1/BST1	25
GO:0035455	response to interferon-alpha	9/1068	21/18722	9.74361091191723e-07	1.3210182030328e-05	BST2/IFITM3/IFIT3/IFIT2/AXL/MX2/IFNAR1/EIF2AK2/ADAR	9
GO:0046637	regulation of alpha-beta T cell differentiation	16/1068	68/18722	9.94454485651842e-07	1.34488130440535e-05	HLA-DRA/HLA-DRB1/CD86/IL18/CD83/LGALS9/LILRB4/NCKAP1L/RHOA/SYK/TGFBR2/PRDM1/RUNX1/SASH3/BCL6/NFKBIZ	16
GO:0043434	response to peptide hormone	49/1068	414/18722	1.03199936206144e-06	1.39216713942089e-05	CYBA/TIMP1/SORL1/STAT1/CYBB/GRB2/ZFP36L1/GNAI2/LYN/UCP2/LPL/RETN/PDK4/TLR2/NR4A2/RHOQ/VPS13C/STAT2/MYO5A/CSK/JAK2/STAT5A/TNFSF10/AGTRAP/OSBPL8/STAT6/BTG2/RAB8B/SOCS3/IL1B/CYFIP1/STAT3/BTG1/SESN3/IQGAP1/ROCK1/APC/PAK1/MAX/NR4A1/PKM/RAB10/EGR1/RAB8A/APPL1/PIK3R1/YWHAG/ZNF106/RAB13	49
GO:0001914	regulation of T cell mediated cytotoxicity	12/1068	39/18722	1.03892944852158e-06	1.39802077412031e-05	HLA-DRA/HLA-DRB1/HLA-A/HLA-B/B2M/HLA-E/HLA-F/NCKAP1L/PTPRC/LILRB1/MR1/STX7	12
GO:0043301	negative regulation of leukocyte degranulation	7/1068	12/18722	1.18545752023447e-06	1.58727761270104e-05	CD84/HMOX1/SPI1/LGALS9/HLA-F/NCKAP1L/CD300A	7
GO:1902563	regulation of neutrophil activation	7/1068	12/18722	1.18545752023447e-06	1.58727761270104e-05	GRN/ITGB2/SPI1/SYK/CD300A/PTAFR/ITGAM	7
GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	10/1068	27/18722	1.20999289894732e-06	1.60815804993097e-05	PTPRC/LYN/SYK/RAP1A/HCK/MYO1G/FGR/PTPRJ/PAK1/APPL1	10
GO:0032703	negative regulation of interleukin-2 production	10/1068	27/18722	1.20999289894732e-06	1.60815804993097e-05	LAPTM5/ZFP36/HAVCR2/LILRB4/PTPRC/GBP1/HOMER3/PRNP/VSIG4/TNFAIP3	10
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	10/1068	27/18722	1.20999289894732e-06	1.60815804993097e-05	PTPRC/LYN/SYK/RAP1A/HCK/MYO1G/FGR/PTPRJ/PAK1/APPL1	10
GO:0019079	viral genome replication	23/1068	131/18722	1.30663424482415e-06	1.73233375554573e-05	IFI27/BST2/ISG15/IFI16/MX1/IFITM3/PLSCR1/OAS1/IFIT1/OAS2/PABPC1/RSAD2/OAS3/APOBEC3C/APOBEC3A/IFIH1/RAB29/EIF2AK2/ADAR/DDX5/FAM111A/CDC42/PCBP2	23
GO:0034103	regulation of tissue remodeling	18/1068	86/18722	1.34746489559646e-06	1.78208837662708e-05	SPP1/GPNMB/CST3/HAMP/CSF1R/IL18/PDK4/SYK/P2RX7/TGFB1/CSK/RUNX1/GPR137B/ADAM8/INPP5D/ATP6AP1/TNFAIP3/ROCK1	18
GO:0010959	regulation of metal ion transport	48/1068	406/18722	1.3707968907717e-06	1.80851345295943e-05	B2M/CYBA/TREM2/CCL3/HAMP/CXCR4/TSPO/FXYD5/CD84/YWHAH/CD63/LGALS3/SLC8A1/ARRB2/GNAI2/LYN/VMP1/CD4/FLNA/HOMER3/CCL4/RHOA/TMBIM6/CORO1A/LILRB1/P2RX7/PRNP/CCR1/LILRB2/KCNAB2/KCNE3/PTPN6/ATP1B1/LILRA2/CD33/GLRX/PTK2B/SLC30A1/CALM3/CAB39/GSTO1/SARAF/KLHL24/BAX/WNK1/KIF5B/ATP1B3/ATP1A1	48
GO:0030866	cortical actin cytoskeleton organization	12/1068	40/18722	1.40750687006711e-06	1.85241635875174e-05	PLEK/LCP1/NCKAP1L/RHOQ/FMNL1/FMNL3/TLN1/ROCK1/ARF6/FMNL2/PLEC/RAB13	12
GO:0019722	calcium-mediated signaling	30/1068	202/18722	1.42065095651516e-06	1.86516607332258e-05	TREM2/CCL3/CXCR4/PLEK/SLC8A1/CLEC7A/PTPRC/GBP1/CD4/HOMER3/CCL4/SYK/LAT2/CIB1/P2RX7/PRNP/CCR1/BTK/MCTP1/CCRL2/TRPM2/ATP1B1/LRRK2/PTK2B/MCOLN1/PTPRJ/BST1/CALM3/GSTO1/TMBIM4	30
GO:0022411	cellular component disassembly	51/1068	443/18722	1.4304928772105e-06	1.87352902073492e-05	CAPG/C1QB/TREM2/C3/C1QA/CTSS/C1QC/CST3/TSPO/PLEK/DNASE2/LCP1/HIF1A/VMP1/LAMP2/TWF2/CIB1/VPS13C/TGFB1/DDIT4/ITGAM/ADAM8/PLK3/MMP2/IRAK3/BNIP3L/ARHGEF2/GABARAP/MCOLN1/CAPZA2/CAPZA1/LRP1/CISD2/SETX/DUSP3/TGFBR1/APC/GSN/ATG3/FLII/CFL1/ADAM10/ARF6/TAOK1/BAX/CHMP3/FLOT1/KIF5B/PIK3R1/CAPZB/CHMP1B	51
GO:0045576	mast cell activation	15/1068	62/18722	1.47879571924475e-06	1.92843858276026e-05	CD84/HMOX1/LGALS9/LYN/PLSCR1/LCP2/SYK/LAT2/CD300A/MILR1/BTK/CD300LF/ADGRE2/FGR/STXBP2	15
GO:0071375	cellular response to peptide hormone stimulus	38/1068	290/18722	1.47956555460109e-06	1.92843858276026e-05	CYBA/SORL1/STAT1/GRB2/ZFP36L1/GNAI2/LYN/UCP2/LPL/PDK4/NR4A2/RHOQ/MYO5A/CSK/JAK2/STAT5A/AGTRAP/OSBPL8/STAT6/RAB8B/SOCS3/IL1B/CYFIP1/STAT3/SESN3/ROCK1/APC/PAK1/MAX/NR4A1/PKM/RAB10/RAB8A/APPL1/PIK3R1/YWHAG/ZNF106/RAB13	38
GO:0051651	maintenance of location in cell	31/1068	213/18722	1.48332585553574e-06	1.92868104011346e-05	APOE/FTL/TMSB4X/CYBA/FTH1/CCL3/SRGN/TSPO/SORL1/CCDC88A/SLC8A1/CHCHD10/PTPRC/LYN/CD4/TMSB10/TWF2/CORO1A/VPS13C/SP100/PTPN6/TRPM2/PTK2B/MCOLN1/ERO1A/CALM3/GSTO1/GSN/MORC3/GAA/BAX	31
GO:0051348	negative regulation of transferase activity	36/1068	268/18722	1.54470308246832e-06	2.00365813293246e-05	APOE/SORL1/DUSP1/PYCARD/ZFP36/SLC8A1/GADD45B/LILRB4/PTPRC/LYN/RB1/CORO1C/CD300A/CSK/PTPN6/DTX3L/SH2B3/SPRED1/IRAK3/PRKAG2/CDKN1A/PTPRJ/IL1B/TNFAIP3/ADAR/PRKAR1A/DUSP3/PAK2/APC/CEBPA/NUP62/GNAQ/RGS2/WNK1/YWHAG/PLEC	36
GO:0006907	pinocytosis	9/1068	22/18722	1.56545813397568e-06	2.02571033355702e-05	PPT1/PYCARD/AXL/DOCK2/NR1H3/EHD4/MAPKAPK3/CDC42/APPL1	9
GO:0051222	positive regulation of protein transport	39/1068	303/18722	1.69318786575137e-06	2.18575160851541e-05	HLA-DRB1/TREM2/CD81/GLUL/ITGB2/SORL1/HIF1A/FLNA/TLR2/CIB1/TLR4/OAZ1/PRNP/TGFB1/ITGAM/JAK2/ADAM8/PLK3/TRPM2/CD33/ATP2C1/ADAM9/RAB29/IL1B/SERP1/RAC1/ABCG1/LRP1/STX4/PAK1/TMEM30A/HCLS1/TMED10/ARF6/ACSL4/CDC42/UBE2D3/KIF5B/PIK3R1	39
GO:0002507	tolerance induction	10/1068	28/18722	1.78617394329917e-06	2.29480823762912e-05	HLA-B/HLA-E/HAVCR2/LGALS9/LILRB4/LYN/TGFBR2/LILRB2/IRAK3/TNFAIP3	10
GO:0031342	negative regulation of cell killing	10/1068	28/18722	1.78617394329917e-06	2.29480823762912e-05	HLA-A/HLA-B/HLA-E/HAVCR2/LGALS9/HLA-F/NCKAP1L/PTPRC/ARRB2/LILRB1	10
GO:0050854	regulation of antigen receptor-mediated signaling pathway	15/1068	63/18722	1.83946971056506e-06	2.35766711596415e-05	LAPTM5/CD81/LGALS3/LILRB4/PTPRC/GBP1/LYN/CMTM3/CD300A/PRNP/PTPN6/LPXN/RAB29/PTPRJ/DUSP3	15
GO:0032733	positive regulation of interleukin-10 production	12/1068	41/18722	1.88715319252107e-06	2.41305180730893e-05	TREM2/ISG15/PYCARD/CLEC7A/CD83/LGALS9/HGF/SYK/TLR2/TLR4/SASH3/STAT3	12
GO:0006887	exocytosis	43/1068	352/18722	2.0576311795769e-06	2.62481745744609e-05	CCL3/ITGB2/CD84/PLEK/HMOX1/SPI1/LGALS9/HLA-F/NCKAP1L/GNAI2/LYN/SYNGR2/SDCBP/SYK/LAT2/CD300A/CORO1A/RAP1A/TNFAIP2/CCR1/HCK/PTAFR/MILR1/ITGAM/BTK/MYO1G/ADGRE2/LRRK2/FGR/RAB8B/STXBP2/RALA/ATP6AP1/STX4/CALM3/ARL8B/PAK1/TMED10/LAMP1/RAB10/RAB8A/RAB7A/RAB13	43
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	14/1068	56/18722	2.16317028923386e-06	2.75294030205328e-05	HLA-DRA/HLA-DRB1/TYROBP/HLA-A/HLA-B/B2M/HLA-E/SPI1/HLA-F/PTPRC/ITGAM/MR1/LAMP1/STX7	14
GO:0051403	stress-activated MAPK cascade	33/1068	239/18722	2.26945917925227e-06	2.88141217205771e-05	TREM2/DUSP1/PYCARD/ZFP36/SPI1/CLEC7A/GADD45B/LGALS9/ZFP36L1/HGF/SDCBP/TAOK3/TLR7/SIRPA/PTGER4/TLR4/VEGFA/MDFIC/SCIMP/NCF1/IRAK1/RASSF2/LRRK2/MYD88/RAP2A/PTK2B/IL1B/EIF2AK2/DUSP3/PJA2/CDC42/TAOK1/LTBR	33
GO:0030225	macrophage differentiation	13/1068	49/18722	2.41605704119178e-06	3.06033891884292e-05	HLA-DRB1/C1QC/SPI1/ID2/CSF1R/RB1/CD4/TLR2/VEGFA/TGFB1/CEBPA/HCLS1/CDC42	13
GO:2001198	regulation of dendritic cell differentiation	7/1068	13/18722	2.44158637824638e-06	3.07839561654424e-05	HLA-B/TMEM176B/LGALS9/TMEM176A/LILRB1/LILRB2/CEBPB	7
GO:1903306	negative regulation of regulated secretory pathway	9/1068	23/18722	2.44172224588757e-06	3.07839561654424e-05	CD84/HMOX1/SPI1/LGALS9/HLA-F/NCKAP1L/GNAI2/CD300A/RAP1A	9
GO:0030890	positive regulation of B cell proliferation	12/1068	42/18722	2.50561477338449e-06	3.14425519004249e-05	CD74/CD81/TNFSF13B/MEF2C/NCKAP1L/PTPRC/GPR183/TLR4/SASH3/BCL6/CDKN1A/BST1	12
GO:0033003	regulation of mast cell activation	12/1068	42/18722	2.50561477338449e-06	3.14425519004249e-05	CD84/HMOX1/LGALS9/LYN/PLSCR1/SYK/CD300A/MILR1/CD300LF/ADGRE2/FGR/STXBP2	12
GO:2000106	regulation of leukocyte apoptotic process	17/1068	81/18722	2.532696408804e-06	3.17086538791331e-05	CD74/LGALS3/LGALS9/HIF1A/MEF2C/LYN/AXL/LILRB1/IRF7/BTK/ADAM8/BCL6/TSC22D3/ADAM17/HCLS1/FNIP1/BAX	17
GO:0043112	receptor metabolic process	26/1068	166/18722	2.58366299636606e-06	3.21338129813448e-05	APOE/FCER1G/LAPTM5/CD9/CD81/ITGB2/SORL1/LGMN/CD63/GRB2/LILRB4/CD36/ARRB2/SDCBP/SYK/LILRB1/VEGFA/TGFB1/DTX3L/RIN3/ARAP1/RAB29/LRP1/NUMB/PICALM/FLOT1	26
GO:0001916	positive regulation of T cell mediated cytotoxicity	10/1068	29/18722	2.58722693848844e-06	3.21338129813448e-05	HLA-DRA/HLA-DRB1/HLA-A/HLA-B/B2M/HLA-E/HLA-F/PTPRC/MR1/STX7	10
GO:2000406	positive regulation of T cell migration	10/1068	29/18722	2.58722693848844e-06	3.21338129813448e-05	AIF1/PYCARD/RHOA/TNFRSF14/ADAM8/ITGA4/SPN/ADAM17/ADAM10/WNK1	10
GO:0072676	lymphocyte migration	21/1068	117/18722	2.59047602796237e-06	3.21338129813448e-05	AIF1/CCL3/CCL3L3/CXCL16/PYCARD/MSN/CKLF/GPR183/CCL4/RHOA/TNFRSF14/ADAM8/ITGA4/MYO1G/SPN/ITGAL/PTK2B/ADAM17/ADAM10/WNK1/PLEC	21
GO:0042542	response to hydrogen peroxide	24/1068	146/18722	2.61196440752823e-06	3.23260549151888e-05	GPX1/TXNIP/SOD2/DUSP1/STAT1/HMOX1/SLC8A1/JUN/HGF/AXL/SIRPA/KLF4/KLF2/TRPM2/LRRK2/PTK2B/STAT6/ADAM9/TNFAIP3/LDHA/SETX/RHOB/UBE3A/PPIF	24
GO:0051090	regulation of DNA-binding transcription factor activity	50/1068	440/18722	2.63749443866085e-06	3.25673226338992e-05	TMSB4X/SGK1/NUPR1/MTDH/PYCARD/HMOX1/SPI1/ID2/HAVCR2/CLEC7A/IL18/LGALS9/CD36/ARRB2/RB1/FLNA/SYK/TRIM22/TLR2/CIB1/HSPA1A/TLR4/KLF4/PRNP/VEGFA/SP100/CARD16/HCK/ADORA3/IRAK1/BTK/CAMK1D/JAK2/ADAM8/SGK3/NFKBIE/TRIM14/IRAK3/MYD88/ARHGEF2/TRIM38/IL1B/STAT3/TNFAIP3/EIF2AK2/RGCC/NFKBIA/BHLHE40/HCLS1/FLOT1	50
GO:0050848	regulation of calcium-mediated signaling	16/1068	73/18722	2.72535995740298e-06	3.35273008207164e-05	TREM2/CCL3/PLEK/CLEC7A/GBP1/CD4/HOMER3/CCL4/SYK/CIB1/PRNP/LRRK2/PTK2B/BST1/CALM3/TMBIM4	16
GO:0045055	regulated exocytosis	32/1068	230/18722	2.7276658747766e-06	3.35273008207164e-05	CCL3/ITGB2/CD84/PLEK/HMOX1/SPI1/LGALS9/HLA-F/NCKAP1L/GNAI2/LYN/SYNGR2/SYK/LAT2/CD300A/CORO1A/RAP1A/HCK/PTAFR/MILR1/ITGAM/BTK/ADGRE2/LRRK2/FGR/STXBP2/STX4/CALM3/ARL8B/TMED10/LAMP1/RAB10	32
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	8/1068	18/18722	2.85984222000314e-06	3.50720650434931e-05	HLA-A/HLA-B/HLA-E/HAVCR2/LGALS9/HLA-F/ARRB2/LILRB1	8
GO:0038093	Fc receptor signaling pathway	13/1068	50/18722	3.09564311530454e-06	3.78777556693498e-05	FCER1G/PTPRC/LYN/SYK/FCGR1B/RAP1A/HCK/BTK/MYO1G/FGR/PTPRJ/PAK1/APPL1	13
GO:0001952	regulation of cell-matrix adhesion	22/1068	128/18722	3.18191734476761e-06	3.88453076750363e-05	LIMS1/CD36/RHOA/CORO1C/CIB1/VEGFA/PLAU/PLEKHA2/RIN2/BCL6/RRAS/PTK2B/PTPRJ/RAC1/LRP1/BST1/DUSP3/IQGAP1/ROCK1/RCC2/PIK3R1/S100A10	22
GO:0002861	regulation of inflammatory response to antigenic stimulus	12/1068	43/18722	3.29616221043596e-06	4.01491902652651e-05	HLA-DRB1/GPX1/TREM2/C3/CD81/HLA-E/LYN/SYK/HCK/BTK/RHBDF2/FGR	12
GO:0007599	hemostasis	31/1068	222/18722	3.5984030766164e-06	4.37319436968966e-05	APOE/FCER1G/CD9/PLAUR/PLEK/SERPINA1/ACTB/CD36/RAP2B/LYN/FLNA/PLSCR1/SYK/FERMT3/AXL/TLR4/WAS/HPSE/PLAU/PTPN6/JAK2/SH2B3/ENTPD1/FLI1/TLN1/VKORC1/JMJD1C/SERPING1/PABPC4/CLIC1/GNAQ	31
GO:0010975	regulation of neuron projection development	50/1068	445/18722	3.64130044738272e-06	4.41538364361284e-05	APOE/SPP1/LGALS1/VIM/B2M/CTSZ/GRN/YWHAH/CCDC88A/SKIL/LYN/HGF/ACTR2/PLXNC1/FLNA/RHOA/TWF2/CIB1/RAP1A/KLF4/VEGFA/SDC2/PREX1/PLXND1/PMP22/ABI3/CAMK1D/TANC2/LRRK2/ARHGAP4/SCARB2/RAP2A/PTK2B/RAB29/CYFIP1/SHTN1/LRP1/SETX/IQGAP1/RTN4/PAK2/PAK1/TMEM30A/CFL1/DENND5A/ADAM10/ARF6/RGS2/UBE3A/DBNL	50
GO:0045577	regulation of B cell differentiation	10/1068	30/18722	3.68301284105816e-06	4.44598149672256e-05	ZFP36L2/ID2/ZFP36L1/NCKAP1L/SYK/IL4I1/PTPN6/BTK/INPP5D/PPP2R3C	10
GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	10/1068	30/18722	3.68301284105816e-06	4.44598149672256e-05	LAPTM5/LGALS3/LILRB4/GBP1/CD300A/PRNP/PTPN6/LPXN/PTPRJ/DUSP3	10
GO:0007035	vacuolar acidification	9/1068	24/18722	3.70923343359779e-06	4.46763919814591e-05	GRN/PPT1/SLC11A1/ATP6V0D1/ATP6AP2/DMXL2/TCIRG1/ATP6V0A1/ATP6V0E1	9
GO:0150115	cell-substrate junction organization	19/1068	101/18722	3.74600056825977e-06	4.50187507045205e-05	LIMS1/RHOA/CORO1C/VEGFA/TLN1/PTK2B/PTPRJ/RAB8B/RAC1/LRP1/DUSP3/IQGAP1/ROCK1/LAMTOR2/ARF6/RCC2/PIK3R1/PLEC/S100A10	19
GO:0043409	negative regulation of MAPK cascade	27/1068	180/18722	3.8863304819992e-06	4.66014206241504e-05	APOE/TREM2/SORL1/DUSP1/LILRB4/PTPRC/GBP1/LYN/TAOK3/CD300A/SIRPA/TLR4/P2RX7/KLF4/CSK/PTPN6/SH2B3/SPRED1/IRAK3/DUSP2/RNF149/PTPRJ/IL1B/DUSP3/NUP62/RGS2/ATF3	27
GO:0071901	negative regulation of protein serine/threonine kinase activity	21/1068	120/18722	3.94006858047877e-06	4.7141042262225e-05	APOE/SORL1/DUSP1/PYCARD/SLC8A1/LYN/RB1/CD300A/PTPN6/SH2B3/IRAK3/PRKAG2/CDKN1A/PTPRJ/IL1B/TNFAIP3/PRKAR1A/APC/CEBPA/NUP62/RGS2	21
GO:0072665	protein localization to vacuole	15/1068	67/18722	4.20208489510569e-06	5.01647125973236e-05	LAPTM5/CD81/SORL1/MFSD1/GBP1/LAMP2/M6PR/VPS13C/GPR137B/SCARB2/TNFAIP3/LAMTOR4/RTN4/ZFYVE16/RAB7A	15
GO:0017157	regulation of exocytosis	29/1068	202/18722	4.22383933484152e-06	5.03131060724169e-05	ITGB2/CD84/HMOX1/SPI1/LGALS9/HLA-F/NCKAP1L/GNAI2/LYN/SDCBP/SYK/CD300A/RAP1A/PTAFR/ITGAM/ADGRE2/LRRK2/FGR/RAB8B/STXBP2/RALA/ATP6AP1/STX4/CALM3/LAMP1/RAB10/RAB8A/RAB7A/RAB13	29
GO:0002369	T cell cytokine production	11/1068	37/18722	4.28107368340514e-06	5.07531499587859e-05	HLA-A/B2M/CD81/IL18/LILRB4/HLA-F/TNFRSF1B/RSAD2/SASH3/DENND1B/IL1B	11
GO:0002724	regulation of T cell cytokine production	11/1068	37/18722	4.28107368340514e-06	5.07531499587859e-05	HLA-A/B2M/CD81/IL18/LILRB4/HLA-F/TNFRSF1B/RSAD2/SASH3/DENND1B/IL1B	11
GO:0045124	regulation of bone resorption	12/1068	44/18722	4.29840428672445e-06	5.07531499587859e-05	SPP1/HAMP/CSF1R/PDK4/SYK/P2RX7/CSK/GPR137B/ADAM8/INPP5D/ATP6AP1/TNFAIP3	12
GO:0097178	ruffle assembly	12/1068	44/18722	4.29840428672445e-06	5.07531499587859e-05	AIF1/SNX10/CORO1C/RHOG/ABI3/CYFIP1/RAC1/ARHGAP24/ARF6/RCC2/DBNL/PFN1	12
GO:2001234	negative regulation of apoptotic signaling pathway	31/1068	224/18722	4.34607558454307e-06	5.12039822143983e-05	CD74/GPX1/PLAUR/CD44/SOD2/HMOX1/LGALS3/HIF1A/ARRB2/GNAI2/RB1/HGF/PEA15/TMBIM6/NR4A2/HSPA1A/ACAA2/BID/LRRK2/ARHGEF2/SLC35F6/MCL1/IL1B/TNFAIP3/GRINA/TGFBR1/IVNS1ABP/ZNF385A/HERPUD1/BAX/PPIF	31
GO:1902106	negative regulation of leukocyte differentiation	19/1068	102/18722	4.36075464995045e-06	5.12649936625984e-05	CD74/MAFB/CCL3/C1QC/ID2/TMEM176B/LILRB4/FGL2/LYN/TMEM176A/LILRB1/TLR4/LILRB3/RUNX1/GPR137B/BCL6/INPP5D/IRF1/PIK3R1	19
GO:0061572	actin filament bundle organization	25/1068	161/18722	4.68981664753916e-06	5.49270024453932e-05	MARCKS/AIF1/GPR65/PLEK/CCDC88A/LCP1/PHACTR1/FLNA/RHOA/PTGER4/ZYX/WAS/PTK2B/ARAP1/RAC1/SHTN1/RGCC/TGFBR1/PAK2/ROCK1/PAK1/CDC42/PIK3R1/PFN1/S100A10	25
GO:0002716	negative regulation of natural killer cell mediated immunity	8/1068	19/18722	4.69261455287737e-06	5.49270024453932e-05	HLA-A/HLA-B/HLA-E/HAVCR2/LGALS9/HLA-F/ARRB2/LILRB1	8
GO:0032720	negative regulation of tumor necrosis factor production	16/1068	76/18722	4.76438976015729e-06	5.56464223935254e-05	GPNMB/TREM2/ACP5/TSPO/HAVCR2/LGALS9/ARRB2/AXL/SIRPA/LILRB1/TLR4/PTPN6/CLEC4A/IRAK3/CD33/TNFAIP3	16
GO:0009410	response to xenobiotic stimulus	51/1068	462/18722	4.84373998651007e-06	5.64510172077934e-05	LGALS1/B2M/GPX1/CYBA/TXNIP/CXCR4/TSPO/PLIN2/SOD2/FBP1/FOS/STAT1/HMOX1/SLC8A1/CYBB/JUN/TIMP2/MEF2C/NCKAP1L/LYN/RB1/LPL/RHOA/NCEH1/MGST1/AHR/RAP1A/PRNP/AGPAT2/ENG/TGFBR2/APOBEC3A/RNF149/ACSL1/RAP2A/PARP4/PTK2B/CDKN1A/VKORC1/IL1B/STAT3/CPT1A/LDHA/VEGFB/ABCA1/FOSB/ADAM17/GSTO1/SLC1A3/ATP1A1/S100A10	51
GO:1901136	carbohydrate derivative catabolic process	26/1068	172/18722	5.05387050948052e-06	5.87730285973209e-05	TYMP/CST3/CD44/SAMHD1/ALDH1A1/UPP1/NUDT3/DPYD/MGAT1/TGFB1/GNPDA1/HPSE/AOAH/GALC/APOBEC3C/APOBEC3A/IDS/GNS/HPRT1/MBD4/ACAT1/MAN1A1/NPL/NAGK/HEXA/GM2A	26
GO:1903532	positive regulation of secretion by cell	36/1068	282/18722	5.07705828706592e-06	5.89157129398015e-05	SPP1/HLA-DRB1/TREM2/GLUL/ITGB2/HIF1A/HLA-F/SDCBP/RETN/SYK/TLR2/TLR4/TGFB1/PTAFR/ITGAM/JAK2/ADAM8/TRPM2/CD33/FGR/ADAM9/RAB8B/IL1B/SERP1/RAC1/ABCG1/ATP6AP1/RGCC/LRP1/STX4/TMED10/LAMP1/ARF6/ACSL4/KIF5B/RAB7A	36
GO:0042267	natural killer cell mediated cytotoxicity	15/1068	68/18722	5.10990482230959e-06	5.91246454988553e-05	HLA-A/HLA-B/HLA-E/HAVCR2/IL18/LGALS9/HLA-F/ARRB2/CORO1A/LILRB1/SLAMF7/PTPN6/ARL8B/LAMP1/KIF5B	15
GO:0033002	muscle cell proliferation	33/1068	248/18722	5.11697728835534e-06	5.91246454988553e-05	APOE/CYBA/AIF1/SOD2/STAT1/HMOX1/ID2/IL18/JUN/MEF2C/GNAI2/RHOA/TLR4/HBEGF/KLF4/TGFB1/TGFBR2/PTAFR/RUNX1/IRAK1/JAK2/NQO2/IL6R/NAMPT/MMP2/MYD88/CDKN1A/GNA13/STAT3/TNFAIP3/PRKAR1A/TGFBR1/PAK1	33
GO:1990266	neutrophil migration	21/1068	122/18722	5.16546649493501e-06	5.95573871937379e-05	CD74/FCER1G/CCL3/CCL3L3/ITGB2/C5AR1/LGALS3/C3AR1/NCKAP1L/CKLF/PECAM1/CCL4/SYK/RHOG/PREX1/TREM1/CAMK1D/ADAM8/MYD88/RAC1/BST1	21
GO:0051092	positive regulation of NF-kappaB transcription factor activity	24/1068	152/18722	5.37973492927723e-06	6.18956283121107e-05	MTDH/PYCARD/CLEC7A/IL18/LGALS9/CD36/TRIM22/TLR2/CIB1/HSPA1A/TLR4/CARD16/IRAK1/BTK/ADAM8/TRIM14/IRAK3/MYD88/ARHGEF2/TRIM38/IL1B/STAT3/EIF2AK2/FLOT1	24
GO:0032418	lysosome localization	16/1068	77/18722	5.69921622540466e-06	6.52107610126941e-05	CD84/HMOX1/LGALS9/LYN/SYK/LAT2/CD300A/MILR1/BTK/ADGRE2/FGR/BLOC1S1/STXBP2/BLOC1S2/ARL8B/KIF5B	16
GO:0010742	macrophage derived foam cell differentiation	11/1068	38/18722	5.71621385452267e-06	6.52107610126941e-05	MSR1/STAT1/IL18/CD36/SOAT1/LPL/TGFB1/NR1H3/ABCG1/NFKBIA/ABCA1	11
GO:0046633	alpha-beta T cell proliferation	11/1068	38/18722	5.71621385452267e-06	6.52107610126941e-05	HLA-A/CD81/HLA-E/IL18/LGALS9/PTPRC/SYK/DOCK2/TNFRSF14/TGFBR2/IRF1	11
GO:0090077	foam cell differentiation	11/1068	38/18722	5.71621385452267e-06	6.52107610126941e-05	MSR1/STAT1/IL18/CD36/SOAT1/LPL/TGFB1/NR1H3/ABCG1/NFKBIA/ABCA1	11
GO:1904951	positive regulation of establishment of protein localization	39/1068	319/18722	5.96080290315079e-06	6.78575790409318e-05	HLA-DRB1/TREM2/CD81/GLUL/ITGB2/SORL1/HIF1A/FLNA/TLR2/CIB1/TLR4/OAZ1/PRNP/TGFB1/ITGAM/JAK2/ADAM8/PLK3/TRPM2/CD33/ATP2C1/ADAM9/RAB29/IL1B/SERP1/RAC1/ABCG1/LRP1/STX4/PAK1/TMEM30A/HCLS1/TMED10/ARF6/ACSL4/CDC42/UBE2D3/KIF5B/PIK3R1	39
GO:2000117	negative regulation of cysteine-type endopeptidase activity	17/1068	86/18722	5.99322372573778e-06	6.80830215243811e-05	GPX1/PLAUR/CD44/IFI16/ARRB2/HGF/NAIP/KLF4/VEGFA/CARD16/RPS6KA1/RPS6KA3/PAK2/NR4A1/FNIP1/HERPUD1/XIAP	17
GO:0038061	NIK/NF-kappaB signaling	23/1068	143/18722	6.11788762310205e-06	6.93353876999417e-05	TMSB4X/LAPTM5/TREM2/LIMS1/CD14/LITAF/CD86/SPI1/HAVCR2/IL18/LGALS9/RHOA/TLR7/TLR2/REL/TLR4/IFI35/IRAK1/RASSF2/C20orf27/IL1B/EIF2AK2/NFKBIA	23
GO:0070302	regulation of stress-activated protein kinase signaling cascade	28/1068	195/18722	6.12916603648484e-06	6.93353876999417e-05	TREM2/DUSP1/PYCARD/SPI1/CLEC7A/GADD45B/LYN/HGF/SDCBP/TAOK3/SIRPA/RNF13/TLR4/VEGFA/MDFIC/SCIMP/NCF1/RASSF2/MYD88/RAP2A/PTK2B/IL1B/EIF2AK2/DUSP3/PJA2/CDC42/TAOK1/LTBR	28
GO:0043620	regulation of DNA-templated transcription in response to stress	13/1068	53/18722	6.25696148454036e-06	7.06329794363594e-05	HMOX1/JUN/HIF1A/TMBIM6/HSPA1A/VEGFA/KLF2/RPS6KA1/CEBPB/RPS6KA3/BACH1/ATF3/EGR1	13
GO:0007596	blood coagulation	30/1068	217/18722	6.30310248334462e-06	7.10053048019365e-05	APOE/FCER1G/CD9/PLAUR/PLEK/SERPINA1/ACTB/CD36/RAP2B/LYN/FLNA/PLSCR1/SYK/FERMT3/AXL/TLR4/WAS/HPSE/PLAU/PTPN6/JAK2/SH2B3/ENTPD1/TLN1/VKORC1/JMJD1C/SERPING1/PABPC4/CLIC1/GNAQ	30
GO:2000401	regulation of lymphocyte migration	14/1068	61/18722	6.42230555192191e-06	7.21974182461888e-05	AIF1/CCL3/PYCARD/MSN/CCL4/RHOA/TNFRSF14/ADAM8/ITGA4/SPN/PTK2B/ADAM17/ADAM10/WNK1	14
GO:0010466	negative regulation of peptidase activity	34/1068	262/18722	6.44319818809315e-06	7.22816994240138e-05	GPX1/C3/CSTB/TIMP1/CST3/PLAUR/BST2/CD44/SORL1/IFI16/SERPINA1/A2M/TIMP2/ARRB2/HGF/NAIP/KLF4/PRNP/VEGFA/CARD16/RPS6KA1/CSTA/SERPINB8/SERPING1/LRP1/RPS6KA3/PAK2/ROCK1/NR4A1/TMED10/PICALM/FNIP1/HERPUD1/XIAP	34
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	16/1068	78/18722	6.79470403605914e-06	7.59093643448761e-05	GPX1/PLAUR/CD44/ARRB2/HGF/NAIP/KLF4/VEGFA/CARD16/RPS6KA1/RPS6KA3/PAK2/NR4A1/FNIP1/HERPUD1/XIAP	16
GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	16/1068	78/18722	6.79470403605914e-06	7.59093643448761e-05	GPNMB/TREM2/ACP5/TSPO/HAVCR2/LGALS9/ARRB2/AXL/SIRPA/LILRB1/TLR4/PTPN6/CLEC4A/IRAK3/CD33/TNFAIP3	16
GO:0010821	regulation of mitochondrion organization	23/1068	144/18722	6.89462382742423e-06	7.68665086214486e-05	GPX1/TREM2/PLAUR/TSPO/PYCARD/CHCHD10/HIF1A/ARRB2/HGF/HSPA1A/VPS13C/STAT2/VAT1/ACAA2/BID/LRRK2/TNFSF10/BNIP3L/SLC35F6/RALA/DDHD1/BAX/PPIF	23
GO:0019915	lipid storage	17/1068	87/18722	7.0578500813909e-06	7.85240392560522e-05	APOE/MSR1/TREM2/C3/PLIN2/CD36/SOAT1/LPL/NR1H3/OSBPL8/IL1B/ABCG1/NFKBIA/CPT1A/ABCA1/ALKBH7/GM2A	17
GO:0045851	pH reduction	12/1068	46/18722	7.13349600008152e-06	7.90397215943324e-05	GRN/PPT1/SLC11A1/ATP6V0D1/ATP6AP2/DMXL2/TCIRG1/ATP6V0A1/ATP6AP1/ATP6V0E1/UBE3A/RAB7A	12
GO:0061462	protein localization to lysosome	12/1068	46/18722	7.13349600008152e-06	7.90397215943324e-05	LAPTM5/CD81/SORL1/MFSD1/LAMP2/M6PR/GPR137B/SCARB2/LAMTOR4/RTN4/ZFYVE16/RAB7A	12
GO:0010951	negative regulation of endopeptidase activity	33/1068	252/18722	7.22631728668663e-06	7.99041149159038e-05	GPX1/C3/CSTB/TIMP1/CST3/PLAUR/BST2/CD44/SORL1/IFI16/SERPINA1/A2M/TIMP2/ARRB2/HGF/NAIP/KLF4/PRNP/VEGFA/CARD16/RPS6KA1/CSTA/SERPINB8/SERPING1/RPS6KA3/PAK2/ROCK1/NR4A1/TMED10/PICALM/FNIP1/HERPUD1/XIAP	33
GO:0120032	regulation of plasma membrane bounded cell projection assembly	27/1068	186/18722	7.27205588363142e-06	8.02454264786813e-05	CCDC88A/ACTR2/ACTR3/CORO1C/TWF2/RHOQ/RHOG/P2RX7/WAS/ABI3/TRPM2/ARAP1/CYFIP1/RALA/RAC1/TGFBR1/APC/ATG3/ARHGAP24/BRK1/ARF6/CDC42/SDCCAG8/RCC2/PIK3R1/CAPZB/PFN1	27
GO:0051047	positive regulation of secretion	38/1068	310/18722	7.3490938608026e-06	8.09300213732466e-05	SPP1/HLA-DRB1/CYBA/TREM2/GLUL/ITGB2/HIF1A/HLA-F/GNAI2/SDCBP/RETN/SYK/TLR2/TLR4/TGFB1/PTAFR/ITGAM/JAK2/ADAM8/TRPM2/CD33/FGR/ADAM9/RAB8B/IL1B/SERP1/RAC1/ABCG1/ATP6AP1/RGCC/LRP1/STX4/TMED10/LAMP1/ARF6/ACSL4/KIF5B/RAB7A	38
GO:0098543	detection of other organism	8/1068	20/18722	7.43003833118881e-06	8.16547593382786e-05	HLA-DRB1/HLA-A/HLA-B/CLEC7A/TLR2/NAIP/TLR4/TLR1	8
GO:2000249	regulation of actin cytoskeleton reorganization	11/1068	39/18722	7.55371844259454e-06	8.2677210377769e-05	CSF1R/ARHGDIB/GMFG/HCK/ABI3/NOTCH2/TRPM2/PTK2B/HCLS1/CDC42/ARHGDIA	11
GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	11/1068	39/18722	7.55371844259454e-06	8.2677210377769e-05	HLA-DRA/HLA-DRB1/CD81/CD86/IL18/CD83/LGALS9/NCKAP1L/TGFBR2/SASH3/NFKBIZ	11
GO:1901215	negative regulation of neuron death	29/1068	208/18722	7.57284373789737e-06	8.27187546754943e-05	APOE/GPNMB/GRN/SORL1/SOD2/LGMN/PPT1/C5AR1/HMOX1/HIF1A/HLA-F/MEF2C/ARRB2/RHOA/NR4A2/REL/AXL/NAIP/CORO1A/TNFRSF1B/JAK2/ADAM8/LRRK2/PTK2B/BTG2/STAT3/LRP1/CEBPB/BAX	29
GO:1902743	regulation of lamellipodium organization	13/1068	54/18722	7.8141024022685e-06	8.49146526787161e-05	CD44/ACTR2/ACTR3/CORO1C/TWF2/WAS/ABI3/CYFIP1/RAC1/BRK1/CDC42/PIK3R1/CAPZB	13
GO:0030038	contractile actin filament bundle assembly	19/1068	106/18722	7.83682302335074e-06	8.49146526787161e-05	GPR65/CCDC88A/PHACTR1/RHOA/PTGER4/ZYX/WAS/PTK2B/ARAP1/RAC1/RGCC/TGFBR1/PAK2/ROCK1/PAK1/CDC42/PIK3R1/PFN1/S100A10	19
GO:0043149	stress fiber assembly	19/1068	106/18722	7.83682302335074e-06	8.49146526787161e-05	GPR65/CCDC88A/PHACTR1/RHOA/PTGER4/ZYX/WAS/PTK2B/ARAP1/RAC1/RGCC/TGFBR1/PAK2/ROCK1/PAK1/CDC42/PIK3R1/PFN1/S100A10	19
GO:1903707	negative regulation of hemopoiesis	19/1068	106/18722	7.83682302335074e-06	8.49146526787161e-05	CD74/MAFB/CCL3/C1QC/ID2/TMEM176B/LILRB4/FGL2/LYN/TMEM176A/LILRB1/TLR4/LILRB3/RUNX1/GPR137B/BCL6/INPP5D/IRF1/PIK3R1	19
GO:0045428	regulation of nitric oxide biosynthetic process	14/1068	62/18722	7.86416258645271e-06	8.50401228787552e-05	AIF1/ACP5/TSPO/CLEC7A/CD36/SIRPA/TLR4/KLF4/DDAH2/JAK2/KLF2/PTK2B/IL1B/RAC1	14
GO:0002468	dendritic cell antigen processing and presentation	7/1068	15/18722	8.27460498757832e-06	8.91212944370711e-05	HLA-DRA/HLA-DRB1/CD74/CD68/SLC11A1/FGL2/CLEC4A	7
GO:0090594	inflammatory response to wounding	7/1068	15/18722	8.27460498757832e-06	8.91212944370711e-05	TIMP1/GRN/HMOX1/HIF1A/ALOX5/TLR4/TGFB1	7
GO:0019932	second-messenger-mediated signaling	38/1068	312/18722	8.53861297948188e-06	9.17815849348291e-05	APOE/TREM2/CCL3/CXCR4/PLEK/SLC8A1/CLEC7A/CD36/PTPRC/GBP1/CD4/HOMER3/CCL4/SYK/LAT2/CIB1/FPR1/AHR/P2RX7/PRNP/VEGFA/DDAH2/CCR1/BTK/MCTP1/CCRL2/TRPM2/ATP1B1/LRRK2/PTK2B/CAP1/MCOLN1/PTPRJ/BST1/CALM3/GSTO1/TMBIM4/RGS2	38
GO:0043405	regulation of MAP kinase activity	26/1068	177/18722	8.59342237476804e-06	9.20041808219213e-05	APOE/SORL1/DUSP1/LYN/TAOK3/SYK/CD300A/TLR4/VEGFA/TGFB1/CSK/IRAK1/PTPN6/ADAM8/SH2B3/IRAK3/LRRK2/PTK2B/ADAM9/PTPRJ/IL1B/IQGAP1/PAK1/NUP62/AKAP13/RGS2	26
GO:0071453	cellular response to oxygen levels	26/1068	177/18722	8.59342237476804e-06	9.20041808219213e-05	TREM2/HMOX1/SLC8A1/CYBB/HIF1A/ZFP36L1/ATP6V0D1/TMBIM6/EIF4EBP1/VEGFA/CARD16/ATP6V1A/ACAA2/IRAK1/ADAM8/PLK3/NAMPT/BNIP3L/MALAT1/ATP6AP1/RGCC/ERO1A/PGK1/GNB1/BACH1/EGR1	26
GO:0060491	regulation of cell projection assembly	27/1068	188/18722	8.89563701974395e-06	9.5051202690175e-05	CCDC88A/ACTR2/ACTR3/CORO1C/TWF2/RHOQ/RHOG/P2RX7/WAS/ABI3/TRPM2/ARAP1/CYFIP1/RALA/RAC1/TGFBR1/APC/ATG3/ARHGAP24/BRK1/ARF6/CDC42/SDCCAG8/RCC2/PIK3R1/CAPZB/PFN1	27
GO:0002228	natural killer cell mediated immunity	15/1068	71/18722	8.97130134270675e-06	9.54815424955536e-05	HLA-A/HLA-B/HLA-E/HAVCR2/IL18/LGALS9/HLA-F/ARRB2/CORO1A/LILRB1/SLAMF7/PTPN6/ARL8B/LAMP1/KIF5B	15
GO:0150116	regulation of cell-substrate junction organization	15/1068	71/18722	8.97130134270675e-06	9.54815424955536e-05	LIMS1/RHOA/CORO1C/VEGFA/PTPRJ/RAC1/LRP1/DUSP3/IQGAP1/ROCK1/LAMTOR2/ARF6/RCC2/PIK3R1/S100A10	15
GO:0008637	apoptotic mitochondrial changes	19/1068	107/18722	9.0268007068203e-06	9.58831035708708e-05	GPX1/PLAUR/SOD2/PYCARD/CHCHD10/JUN/ARRB2/IFIT2/HGF/HSPA1A/ACAA2/BID/TNFSF10/BNIP3L/SLC35F6/BLOC1S2/ATG3/BAX/PPIF	19
GO:0010761	fibroblast migration	12/1068	47/18722	9.08560942943611e-06	9.63181699041989e-05	SLC8A1/CORO1C/TGFB1/ARHGAP4/SGPL1/RAC1/PAK1/LAMTOR2/RCC2/APPL1/ZFAND5/PLEC	12
GO:0010810	regulation of cell-substrate adhesion	30/1068	221/18722	9.11090299949349e-06	9.63754144595642e-05	LGALS1/LIMS1/CD36/GBP1/FLNA/RHOA/CORO1C/CIB1/VEGFA/PREX1/PLAU/MYADM/PLEKHA2/JAK2/RIN2/BCL6/RRAS/STK4/PTK2B/PTPRJ/RAC1/LRP1/BST1/DUSP3/IQGAP1/ROCK1/CDC42/RCC2/PIK3R1/S100A10	30
GO:0010038	response to metal ion	43/1068	373/18722	9.12673031668593e-06	9.63754144595642e-05	B2M/C1QA/TXNIP/HAMP/TSPO/SOD2/FBP1/LGMN/CD14/FOS/ALOX5AP/DUSP1/MEF2A/HMOX1/CYBB/JUN/JUNB/HIF1A/MEF2C/PLSCR1/SLC25A24/PRNP/AQP9/TCIRG1/CRIP1/HVCN1/NCF1/TRPM2/LRRK2/MT1X/PTK2B/ERCC1/MCOLN1/ADAM9/SLC30A1/ADCY7/FOSB/CALM3/IQGAP1/CEBPA/WNK1/UBE2D3/PPIF	43
GO:0051924	regulation of calcium ion transport	33/1068	255/18722	9.30330153328816e-06	9.80480763156698e-05	CYBA/CCL3/CXCR4/TSPO/CD84/LGALS3/SLC8A1/ARRB2/GNAI2/LYN/VMP1/CD4/HOMER3/CCL4/RHOA/TMBIM6/CORO1A/LILRB1/P2RX7/PRNP/CCR1/LILRB2/KCNE3/PTPN6/ATP1B1/LILRA2/CD33/PTK2B/SLC30A1/CALM3/GSTO1/SARAF/BAX	33
GO:0051017	actin filament bundle assembly	24/1068	157/18722	9.49780444095149e-06	9.99028318974157e-05	MARCKS/AIF1/GPR65/PLEK/CCDC88A/LCP1/PHACTR1/FLNA/RHOA/PTGER4/ZYX/WAS/PTK2B/ARAP1/RAC1/RGCC/TGFBR1/PAK2/ROCK1/PAK1/CDC42/PIK3R1/PFN1/S100A10	24
GO:0032633	interleukin-4 production	10/1068	33/18722	9.69971060086903e-06	0.000101237211609844	HLA-DRB1/FCER1G/HLA-E/CD86/HAVCR2/CD83/LGALS9/SYK/SASH3/CEBPB	10
GO:0032673	regulation of interleukin-4 production	10/1068	33/18722	9.69971060086903e-06	0.000101237211609844	HLA-DRB1/FCER1G/HLA-E/CD86/HAVCR2/CD83/LGALS9/SYK/SASH3/CEBPB	10
GO:0045920	negative regulation of exocytosis	10/1068	33/18722	9.69971060086903e-06	0.000101237211609844	CD84/HMOX1/SPI1/LGALS9/HLA-F/NCKAP1L/GNAI2/CD300A/RAP1A/RAB7A	10
GO:0150117	positive regulation of cell-substrate junction organization	10/1068	33/18722	9.69971060086903e-06	0.000101237211609844	LIMS1/VEGFA/PTPRJ/RAC1/DUSP3/IQGAP1/ROCK1/ARF6/PIK3R1/S100A10	10
GO:0007266	Rho protein signal transduction	22/1068	137/18722	9.93160584247236e-06	0.000103457423023129	APOE/GPR65/ARHGDIB/RHOA/LPAR6/RHOG/WAS/MYO9B/BCL6/ARHGAP4/ARHGEF2/GNA13/RAC1/SHTN1/ABCA1/ROCK1/RHOB/CFL1/AKAP13/CDC42/FLOT1/ARHGDIA	22
GO:0042742	defense response to bacterium	41/1068	350/18722	9.95991012518342e-06	0.000103481075159121	HLA-A/FCER1G/CYBA/TREM2/ACP5/LYZ/GRN/HAMP/HLA-E/ISG15/PYCARD/C5AR1/HAVCR2/SLC11A1/CD36/CD4/RNASE6/SYK/TLR2/OAS1/GBP4/NAIP/OAS2/IRF8/TNFRSF14/CASP1/TLR4/GBP2/TREM1/STAB1/TLR5/NOTCH2/OAS3/IL6R/SPN/FGR/MYD88/MR1/CEBPB/TNFRSF1A/ADAM17	41
GO:0050817	coagulation	30/1068	222/18722	9.97223111244312e-06	0.000103481075159121	APOE/FCER1G/CD9/PLAUR/PLEK/SERPINA1/ACTB/CD36/RAP2B/LYN/FLNA/PLSCR1/SYK/FERMT3/AXL/TLR4/WAS/HPSE/PLAU/PTPN6/JAK2/SH2B3/ENTPD1/TLN1/VKORC1/JMJD1C/SERPING1/PABPC4/CLIC1/GNAQ	30
GO:0001894	tissue homeostasis	34/1068	268/18722	1.05417137075033e-05	0.000109180589569459	SPP1/B2M/ACP5/LYZ/LIPA/HAMP/CTSH/SNX10/TPP1/CSF1R/ACTB/ALDH1A1/RB1/PECAM1/PDK4/SYK/OAS1/CORO1A/MBP/TLR4/P2RX7/DRAM2/VEGFA/TCIRG1/CSK/GPR137B/ADAM8/SASH3/INPP5D/PTK2B/RAC1/ATP6AP1/TNFAIP3/BAX	34
GO:0002534	cytokine production involved in inflammatory response	15/1068	72/18722	1.07411979452739e-05	0.000110821231573036	TREM2/PYCARD/PLD3/CLEC7A/LILRB4/HIF1A/GPSM3/SIRPA/ALOX5/TLR4/GBP5/MYD88/STAT3/ADCY7/APPL1	15
GO:1900015	regulation of cytokine production involved in inflammatory response	15/1068	72/18722	1.07411979452739e-05	0.000110821231573036	TREM2/PYCARD/PLD3/CLEC7A/LILRB4/HIF1A/GPSM3/SIRPA/ALOX5/TLR4/GBP5/MYD88/STAT3/ADCY7/APPL1	15
GO:0033209	tumor necrosis factor-mediated signaling pathway	18/1068	99/18722	1.09962252267846e-05	0.000113235937640705	TMSB4X/LAPTM5/LIMS1/TNFSF13B/PYCARD/STAT1/SYK/HSPA1A/TNFRSF1B/TNFRSF14/CASP1/CARD16/JAK2/PTK2B/TNFAIP3/NFKBIA/TNFRSF1A/ADAM17	18
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	21/1068	128/18722	1.11895330461632e-05	0.00011500708631828	PYCARD/SPI1/CLEC7A/GADD45B/LYN/SDCBP/TAOK3/RNF13/TLR4/VEGFA/SCIMP/NCF1/RASSF2/MYD88/PTK2B/IL1B/EIF2AK2/PJA2/CDC42/TAOK1/LTBR	21
GO:0030641	regulation of cellular pH	16/1068	81/18722	1.1296135522767e-05	0.000115662139052848	GRN/PPT1/SLC11A1/ATP6V0D1/ATP6AP2/SLC4A7/DMXL2/TCIRG1/HVCN1/LRRK2/LACC1/ATP6V0A1/ATP6AP1/ATP6V0E1/UBE3A/RAB7A	16
GO:0046209	nitric oxide metabolic process	16/1068	81/18722	1.1296135522767e-05	0.000115662139052848	GCHFR/AIF1/ACP5/TSPO/CLEC7A/CD36/TLR2/SIRPA/TLR4/KLF4/DDAH2/JAK2/KLF2/PTK2B/IL1B/RAC1	16
GO:0097581	lamellipodium organization	17/1068	90/18722	1.13416618044827e-05	0.000115874403006291	CD44/CCDC88A/PLEKHO1/ACTR2/ACTR3/CORO1C/TWF2/WAS/ABI3/ABI1/CYFIP1/RAC1/ARPC5/BRK1/CDC42/PIK3R1/CAPZB	17
GO:0031668	cellular response to extracellular stimulus	32/1068	246/18722	1.13640658699536e-05	0.000115874403006291	CD68/AIF1/GLUL/FOS/IFI16/HMOX1/JUN/PTPRC/LYN/UPP1/LAMP2/UCP2/LPL/USF2/PDK4/ASGR1/NR4A2/AXL/RRAGD/NAMPT/ITGA4/LRRK2/PRKAG2/GABARAP/CDKN1A/EIF2AK2/SESN3/MAX/KLF10/FNIP1/ATF3/PLEC	32
GO:0010878	cholesterol storage	8/1068	21/18722	1.14027627865716e-05	0.000115874403006291	MSR1/TREM2/CD36/SOAT1/LPL/NR1H3/ABCG1/ABCA1	8
GO:0046641	positive regulation of alpha-beta T cell proliferation	8/1068	21/18722	1.14027627865716e-05	0.000115874403006291	HLA-A/CD81/HLA-E/IL18/LGALS9/PTPRC/SYK/TGFBR2	8
GO:0043303	mast cell degranulation	12/1068	48/18722	1.14900887780226e-05	0.000116542329034229	CD84/HMOX1/LGALS9/LYN/SYK/LAT2/CD300A/MILR1/BTK/ADGRE2/FGR/STXBP2	12
GO:0080164	regulation of nitric oxide metabolic process	14/1068	64/18722	1.16318777319894e-05	0.000117759122404906	AIF1/ACP5/TSPO/CLEC7A/CD36/SIRPA/TLR4/KLF4/DDAH2/JAK2/KLF2/PTK2B/IL1B/RAC1	14
GO:0043312	neutrophil degranulation	6/1068	11/18722	1.22505097487669e-05	0.000123098232037889	ITGB2/SPI1/SYK/PTAFR/ITGAM/STXBP2	6
GO:0046598	positive regulation of viral entry into host cell	6/1068	11/18722	1.22505097487669e-05	0.000123098232037889	HLA-DRB1/CD74/LGALS1/LGALS9/CD4/TRIM38	6
GO:0075294	positive regulation by symbiont of entry into host	6/1068	11/18722	1.22505097487669e-05	0.000123098232037889	HLA-DRB1/CD74/LGALS1/LGALS9/CD4/TRIM38	6
GO:0098883	synapse pruning	6/1068	11/18722	1.22505097487669e-05	0.000123098232037889	C1QB/TREM2/C3/C1QA/C1QC/ITGAM	6
GO:0007259	receptor signaling pathway via JAK-STAT	25/1068	170/18722	1.24697030361367e-05	0.000125067876548315	HAMP/STAT1/CSF1R/IL18/PTPRC/LYN/CD300A/IL10RA/JAK1/PARP9/STAT2/JAK2/IL6R/SH2B3/STAT5A/PTK2B/STAT6/IFNAR1/PARP14/SOCS3/STAT3/TNFRSF1A/HCLS1/PIAS1/SOCS6	25
GO:0045807	positive regulation of endocytosis	18/1068	100/18722	1.27052543888959e-05	0.000127193975292175	APOE/B2M/TREM2/C3/CD14/PPT1/CD63/CD36/NCKAP1L/ARRB2/SYK/AXL/VEGFA/LRRK2/LRP1/CDC42/FLOT1/APPL1	18
GO:0050856	regulation of T cell receptor signaling pathway	11/1068	41/18722	1.28175985965983e-05	0.000128081040791194	LAPTM5/CD81/LGALS3/LILRB4/GBP1/CD300A/PRNP/PTPN6/RAB29/PTPRJ/DUSP3	11
GO:0097696	receptor signaling pathway via STAT	26/1068	181/18722	1.29137441832478e-05	0.000128803259912764	HAMP/STAT1/CSF1R/IL18/PTPRC/LYN/CD300A/IL10RA/JAK1/PARP9/STAT2/TGFB1/JAK2/IL6R/SH2B3/STAT5A/PTK2B/STAT6/IFNAR1/PARP14/SOCS3/STAT3/TNFRSF1A/HCLS1/PIAS1/SOCS6	26
GO:0002446	neutrophil mediated immunity	10/1068	34/18722	1.30421490129177e-05	0.000129843977995764	ITGB2/SPI1/SYK/TREM1/PTAFR/ITGAM/MYD88/KMT2E/STXBP2/ADAM17	10
GO:0006885	regulation of pH	17/1068	91/18722	1.32159267482209e-05	0.000131331750890239	GRN/PPT1/SLC11A1/PDK4/ATP6V0D1/ATP6AP2/SLC4A7/DMXL2/TCIRG1/HVCN1/LRRK2/LACC1/ATP6V0A1/ATP6AP1/ATP6V0E1/UBE3A/RAB7A	17
GO:0002312	B cell activation involved in immune response	16/1068	82/18722	1.33007116926044e-05	0.000131689248244575	LGALS1/SPI1/GAPT/PTPRC/GPR183/DOCK10/IRF8/TLR4/CD180/TGFB1/NOTCH2/BCL6/LFNG/PTK2B/STAT6/ERCC1	16
GO:2001057	reactive nitrogen species metabolic process	16/1068	82/18722	1.33007116926044e-05	0.000131689248244575	GCHFR/AIF1/ACP5/TSPO/CLEC7A/CD36/TLR2/SIRPA/TLR4/KLF4/DDAH2/JAK2/KLF2/PTK2B/IL1B/RAC1	16
GO:0050878	regulation of body fluid levels	43/1068	379/18722	1.35704083231769e-05	0.000134113412659089	APOE/FCER1G/CYBA/CD9/PLAUR/PLEK/SERPINA1/ACTB/CD36/RAP2B/HIF1A/GNAI2/LYN/FLNA/PLSCR1/USF2/SYK/FERMT3/AXL/OAS2/TLR4/VEGFA/WAS/HPSE/PLAU/PTPN6/JAK2/NCOR2/NR1H3/SH2B3/STAT5A/ENTPD1/FLI1/TLN1/VKORC1/JMJD1C/SERPING1/PABPC4/PRKACB/CLIC1/GNAQ/WNK1/PLEC	43
GO:1905954	positive regulation of lipid localization	19/1068	110/18722	1.36334848452924e-05	0.000134490464762701	APOE/SPP1/MSR1/TREM2/C3/PLIN2/CD36/LPL/RETN/PLTP/NR1H3/ACSL1/IL1B/ABCG1/LRP1/NFKBIA/ABCA1/TMEM30A/SCP2	19
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	7/1068	16/18722	1.39854040153451e-05	0.000137710292092704	CD84/CLEC7A/LGALS9/SYK/OAS1/OAS3/IL1B	7
GO:0002279	mast cell activation involved in immune response	12/1068	49/18722	1.44330179899676e-05	0.000141601027407027	CD84/HMOX1/LGALS9/LYN/SYK/LAT2/CD300A/MILR1/BTK/ADGRE2/FGR/STXBP2	12
GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	12/1068	49/18722	1.44330179899676e-05	0.000141601027407027	GPX1/HMOX1/LGALS3/SKIL/HGF/PEA15/SP100/STK4/ARHGEF2/TNFAIP3/STX4/ATF3	12
GO:0010883	regulation of lipid storage	13/1068	57/18722	1.47196673386723e-05	0.000143890081448326	MSR1/TREM2/C3/PLIN2/CD36/LPL/NR1H3/OSBPL8/ABCG1/NFKBIA/CPT1A/ABCA1/ALKBH7	13
GO:0033619	membrane protein proteolysis	13/1068	57/18722	1.47196673386723e-05	0.000143890081448326	APOE/TIMP1/CTSH/TIMP2/TNFRSF1B/TGFB1/ADAM8/ADAM9/IL1B/HM13/ROCK1/ADAM17/ADAM10	13
GO:0055067	monovalent inorganic cation homeostasis	23/1068	151/18722	1.53636500987368e-05	0.000149643061250512	GRN/PPT1/SLC8A1/SLC11A1/GNAI2/PDK4/ATP6V0D1/ATP6AP2/SLC4A7/DMXL2/TCIRG1/HVCN1/ATP1B1/LRRK2/LACC1/ATP6V0A1/ATP6AP1/ATP6V0E1/SLC1A3/UBE3A/ATP1B3/ATP1A1/RAB7A	23
GO:2001236	regulation of extrinsic apoptotic signaling pathway	23/1068	151/18722	1.53636500987368e-05	0.000149643061250512	GPX1/PYCARD/HMOX1/LGALS3/SKIL/PTPRC/HGF/PEA15/HSPA1A/SP100/TNFSF12/BID/TNFSF10/STK4/ARHGEF2/MCL1/IL1B/TNFAIP3/STX4/TGFBR1/PAK2/LTBR/ATF3	23
GO:0045671	negative regulation of osteoclast differentiation	9/1068	28/18722	1.59267638319378e-05	0.00015456981589413	MAFB/CCL3/LILRB4/LILRB1/TLR4/LILRB3/GPR137B/INPP5D/PIK3R1	9
GO:0061082	myeloid leukocyte cytokine production	9/1068	28/18722	1.59267638319378e-05	0.00015456981589413	CD74/LAPTM5/HMOX1/CD36/LILRB1/TLR4/TGFB1/BCL6/IRAK3	9
GO:0010591	regulation of lamellipodium assembly	11/1068	42/18722	1.64766896306419e-05	0.000159048689171635	ACTR2/ACTR3/TWF2/WAS/ABI3/CYFIP1/RAC1/BRK1/CDC42/PIK3R1/CAPZB	11
GO:0046596	regulation of viral entry into host cell	11/1068	42/18722	1.64766896306419e-05	0.000159048689171635	HLA-DRB1/CD74/LGALS1/IFITM3/LGALS9/CD4/TRIM22/CIITA/TRIM14/TRIM38/GSN	11
GO:0051452	intracellular pH reduction	11/1068	42/18722	1.64766896306419e-05	0.000159048689171635	GRN/PPT1/SLC11A1/ATP6V0D1/ATP6AP2/DMXL2/TCIRG1/ATP6V0A1/ATP6V0E1/UBE3A/RAB7A	11
GO:0032715	negative regulation of interleukin-6 production	14/1068	66/18722	1.69123737637428e-05	0.000162962801480636	CD84/HAVCR2/LILRB4/NCKAP1L/ARRB2/HGF/SIRPA/TLR4/CSK/PTPN6/KLF2/INPP5D/IRAK3/TNFAIP3	14
GO:0050860	negative regulation of T cell receptor signaling pathway	8/1068	22/18722	1.70240797309121e-05	0.00016345539898221	LAPTM5/LGALS3/LILRB4/GBP1/PRNP/PTPN6/PTPRJ/DUSP3	8
GO:0071404	cellular response to low-density lipoprotein particle stimulus	8/1068	22/18722	1.70240797309121e-05	0.00016345539898221	FCER1G/CD9/CD81/ITGB2/CD36/LPL/SYK/ABCA1	8
GO:0046640	regulation of alpha-beta T cell proliferation	10/1068	35/18722	1.73305146656364e-05	0.000166102055303328	HLA-A/CD81/HLA-E/IL18/LGALS9/PTPRC/SYK/TNFRSF14/TGFBR2/IRF1	10
GO:0001954	positive regulation of cell-matrix adhesion	13/1068	58/18722	1.79907997355497e-05	0.000171730480318536	LIMS1/CD36/CIB1/VEGFA/PLEKHA2/RIN2/RRAS/PTK2B/PTPRJ/RAC1/IQGAP1/ROCK1/S100A10	13
GO:0043525	positive regulation of neuron apoptotic process	13/1068	58/18722	1.79907997355497e-05	0.000171730480318536	TYROBP/CTSZ/CCL3/GRN/NUPR1/JUN/RHOA/PRNP/ITGAM/NQO2/MCL1/CDC42/BAX	13
GO:0002448	mast cell mediated immunity	12/1068	50/18722	1.80132416345981e-05	0.000171730480318536	CD84/HMOX1/LGALS9/LYN/SYK/LAT2/CD300A/MILR1/BTK/ADGRE2/FGR/STXBP2	12
GO:0002292	T cell differentiation involved in immune response	15/1068	75/18722	1.80507049314868e-05	0.000171784133704238	HLA-DRA/HLA-DRB1/FCER1G/CD86/IL18/LGALS9/FGL2/GPR183/PTGER4/IL6R/BCL6/SPN/STAT6/STAT3/NFKBIZ	15
GO:0033157	regulation of intracellular protein transport	30/1068	229/18722	1.84122084730936e-05	0.000174915980494389	CD81/IFI27/ITGB2/SORL1/LCP1/CD36/FLNA/CIB1/OAZ1/PRNP/SP100/TGFB1/MDFIC/ITGAM/JAK2/PLK3/LRRK2/BNIP3L/RAB29/IL1B/NUCB1/PAK1/TMEM30A/NUP62/HCLS1/UHMK1/CDC42/UBE2D3/KIF5B/PIK3R1	30
GO:0045862	positive regulation of proteolysis	42/1068	372/18722	1.91589439018913e-05	0.000181690090148691	APOE/CTSD/LAPTM5/TREM2/GRN/NUPR1/CTSH/LGMN/PYCARD/IFI16/CTSC/CLEC7A/LGALS9/LYN/RHOA/SYK/HSPA1A/MBP/TNFRSF1B/CASP1/BID/JAK2/ADAM8/PLK3/APH1B/LRRK2/TNFSF10/PTK2B/GABARAP/ADAM9/IL1B/STAT3/RPS27L/DAPK1/GSN/CEBPA/PICALM/HERPUD1/BAX/PIAS1/PSME2/SUMO2	42
GO:0032868	response to insulin	33/1068	264/18722	1.92525824979764e-05	0.000182257780980843	SORL1/STAT1/GRB2/ZFP36L1/GNAI2/LYN/UCP2/LPL/RETN/PDK4/TLR2/RHOQ/VPS13C/MYO5A/TNFSF10/OSBPL8/RAB8B/SOCS3/IL1B/CYFIP1/SESN3/APC/PAK1/MAX/PKM/RAB10/EGR1/RAB8A/APPL1/PIK3R1/YWHAG/ZNF106/RAB13	33
GO:0072594	establishment of protein localization to organelle	46/1068	422/18722	1.93196994764364e-05	0.000182572851794835	CD68/LAPTM5/TXNIP/TSPO/SORL1/CD36/LAMP2/SSR3/FLNA/M6PR/NUP214/SYK/IL10RA/VPS13C/TGFB1/MDFIC/BID/JAK2/LRRK2/BNIP3L/SCARB2/CDKN1A/RAB8B/RALA/STAT3/TNFAIP3/KPNA3/SPCS3/NFKBIA/MAN1A1/TRAM1/CALM3/OXA1L/NUP62/HCLS1/LAMP1/HERPUD1/BAX/RAB10/RANBP2/UBE2D3/APPL1/ZFYVE16/PIK3R1/KPNB1/RAB7A	46
GO:0071248	cellular response to metal ion	27/1068	197/18722	2.11133586624022e-05	0.000199174271577487	B2M/TSPO/FBP1/LGMN/FOS/ALOX5AP/MEF2A/HMOX1/CYBB/JUN/JUNB/MEF2C/SLC25A24/PRNP/HVCN1/NCF1/TRPM2/LRRK2/MT1X/MCOLN1/ADCY7/FOSB/IQGAP1/CEBPA/WNK1/UBE2D3/PPIF	27
GO:0006809	nitric oxide biosynthetic process	15/1068	76/18722	2.13178316129613e-05	0.000200649610861426	GCHFR/AIF1/ACP5/TSPO/CLEC7A/CD36/SIRPA/TLR4/KLF4/DDAH2/JAK2/KLF2/PTK2B/IL1B/RAC1	15
GO:0097006	regulation of plasma lipoprotein particle levels	16/1068	85/18722	2.13441209478241e-05	0.000200649610861426	APOE/APOC1/MSR1/TREM2/LIPA/HMOX1/CD36/PLA2G7/SOAT1/LPL/PLTP/NCEH1/CSK/ABCG1/ABCA1/PRKACB	16
GO:0046850	regulation of bone remodeling	12/1068	51/18722	2.23436815448854e-05	0.000209680879332524	SPP1/HAMP/CSF1R/PDK4/SYK/P2RX7/CSK/GPR137B/ADAM8/INPP5D/ATP6AP1/TNFAIP3	12
GO:0010934	macrophage cytokine production	7/1068	17/18722	2.26044181365848e-05	0.000211026713261266	CD74/LAPTM5/CD36/LILRB1/TLR4/TGFB1/IRAK3	7
GO:0010935	regulation of macrophage cytokine production	7/1068	17/18722	2.26044181365848e-05	0.000211026713261266	CD74/LAPTM5/CD36/LILRB1/TLR4/TGFB1/IRAK3	7
GO:0045591	positive regulation of regulatory T cell differentiation	7/1068	17/18722	2.26044181365848e-05	0.000211026713261266	HLA-DRA/HLA-DRB1/LGALS9/LILRB4/IL4I1/LILRB2/BCL6	7
GO:0030224	monocyte differentiation	10/1068	36/18722	2.27764765503121e-05	0.000212265746917935	HLA-DRB1/CD74/IFI16/CSF1R/JUN/ZFP36L1/CD4/VEGFA/IRF7/INPP5D	10
GO:0033004	negative regulation of mast cell activation	6/1068	12/18722	2.33155619772995e-05	0.000216541776987105	CD84/HMOX1/LGALS9/CD300A/MILR1/CD300LF	6
GO:0034154	toll-like receptor 7 signaling pathway	6/1068	12/18722	2.33155619772995e-05	0.000216541776987105	HAVCR2/TLR7/PIK3AP1/UNC93B1/SCIMP/RSAD2	6
GO:0060249	anatomical structure homeostasis	37/1068	314/18722	2.33842793521188e-05	0.000216806823683905	SPP1/B2M/ACP5/LYZ/LIPA/HAMP/CTSH/SNX10/TPP1/CSF1R/ACTB/HIF1A/ALDH1A1/RB1/PECAM1/PDK4/SYK/OAS1/CORO1A/MBP/TLR4/P2RX7/DRAM2/VEGFA/TCIRG1/CSK/GPR137B/ADAM8/SASH3/INPP5D/PTK2B/RAC1/ATP6AP1/TNFAIP3/GAA/TAOK1/BAX	37
GO:0042987	amyloid precursor protein catabolic process	14/1068	68/18722	2.4200153972508e-05	0.000223986330764414	APOE/SORL1/LYN/IFNGR1/PRNP/APH1B/ABCG1/RTN4/ROCK1/ADAM17/RTN3/TMED10/ADAM10/PICALM	14
GO:1902904	negative regulation of supramolecular fiber organization	24/1068	166/18722	2.46298252814386e-05	0.000227572837703155	APOE/TMSB4X/CAPG/TREM2/GMFG/TMSB10/TWF2/CIB1/CORO1A/WAS/MYADM/ARHGEF2/ARAP1/CAPZA2/CAPZA1/PAK2/APC/GSN/FLII/PFDN5/TAOK1/PIK3R1/CAPZB/PFN1	24
GO:0043542	endothelial cell migration	34/1068	279/18722	2.47389563078213e-05	0.000227986396517157	APOE/TMSB4X/GPX1/GRN/GLUL/LGMN/HMOX1/HIF1A/MEF2C/RHOA/CIB1/KLF4/VEGFA/SP100/PLXND1/TNFSF12/TGFB1/VASH1/RIN2/LPXN/STAT5A/SPRED1/RRAS/PTK2B/PRKX/PRCP/RAC1/RGCC/TGFBR1/ADAM17/SVBP/RHOB/NR4A1/RAB13	34
GO:0002758	innate immune response-activating signal transduction	8/1068	23/18722	2.48013370562585e-05	0.000227986396517157	TYROBP/CLEC7A/LYN/SYK/HCK/LILRA2/PAK2/PAK1	8
GO:0050765	negative regulation of phagocytosis	8/1068	23/18722	2.48013370562585e-05	0.000227986396517157	PLSCR1/CD300A/TLR2/SIRPA/CSK/CD300LF/ATG3/APPL1	8
GO:0043524	negative regulation of neuron apoptotic process	22/1068	145/18722	2.4855922328194e-05	0.000228099586535604	APOE/GRN/SOD2/LGMN/PPT1/C5AR1/HMOX1/HIF1A/MEF2C/ARRB2/RHOA/NR4A2/AXL/NAIP/CORO1A/JAK2/ADAM8/PTK2B/BTG2/LRP1/CEBPB/BAX	22
GO:0032231	regulation of actin filament bundle assembly	18/1068	105/18722	2.53519259962286e-05	0.00023225635428803	GPR65/PLEK/CCDC88A/FLNA/RHOA/PTGER4/WAS/ARAP1/RAC1/RGCC/TGFBR1/PAK2/ROCK1/PAK1/CDC42/PIK3R1/PFN1/S100A10	18
GO:0031295	T cell costimulation	11/1068	44/18722	2.65771931462087e-05	0.000243068702062614	LGALS1/CD81/TNFSF13B/CD86/LILRB4/LYN/TNFRSF14/LILRB2/CSK/PTPN6/MAP3K8	11
GO:0010632	regulation of epithelial cell migration	35/1068	292/18722	2.68941424896162e-05	0.000245551256977951	APOE/TMSB4X/GRN/GLUL/CTSH/LGMN/HMOX1/HIF1A/MEF2C/RHOA/CORO1C/CIB1/HBEGF/KLF4/GLIPR2/VEGFA/SP100/TGFB1/TGFBR2/VASH1/RIN2/STAT5A/SPRED1/RRAS/PTK2B/ADAM9/PRCP/RAC1/RGCC/RTN4/ADAM17/SVBP/RHOB/ARF6/PFN1	35
GO:0002218	activation of innate immune response	12/1068	52/18722	2.75527164787471e-05	0.000250293700537575	TYROBP/PYCARD/IFI16/CLEC7A/LYN/MNDA/SYK/TLR4/HCK/LILRA2/PAK2/PAK1	12
GO:0043277	apoptotic cell clearance	12/1068	52/18722	2.75527164787471e-05	0.000250293700537575	TYROBP/TREM2/C3/CD36/MARCO/AXL/RHOG/C2/CD300LF/NR1H3/RAC1/LRP1	12
GO:0045010	actin nucleation	12/1068	52/18722	2.75527164787471e-05	0.000250293700537575	ACTR2/ACTR3/GMFG/CORO1A/ARPC3/WAS/ARPC4/ARPC1B/CYFIP1/GSN/ARPC5/BRK1	12
GO:1903305	regulation of regulated secretory pathway	21/1068	136/18722	2.88404860601415e-05	0.00026155170215214	ITGB2/CD84/HMOX1/SPI1/LGALS9/HLA-F/NCKAP1L/GNAI2/LYN/SYK/CD300A/RAP1A/PTAFR/ITGAM/ADGRE2/LRRK2/FGR/STXBP2/STX4/CALM3/LAMP1	21
GO:0071887	leukocyte apoptotic process	18/1068	106/18722	2.89345606952262e-05	0.000261964579717182	CD74/LGALS3/LGALS9/HIF1A/MEF2C/LYN/AXL/LILRB1/PLEKHO2/IRF7/BTK/ADAM8/BCL6/TSC22D3/ADAM17/HCLS1/FNIP1/BAX	18
GO:0043304	regulation of mast cell degranulation	9/1068	30/18722	2.97495022595322e-05	0.000268891648563544	CD84/HMOX1/LGALS9/LYN/SYK/CD300A/ADGRE2/FGR/STXBP2	9
GO:0051271	negative regulation of cellular component movement	41/1068	367/18722	3.0679824537861e-05	0.000276836677602505	APOE/CD74/CD9/AIF1/TIMP1/BST2/DUSP1/HMOX1/ARHGDIB/RAP2B/MEF2C/RHOA/CORO1C/CD300A/PTGER4/KLF4/WAS/SP100/TGFB1/ENG/VASH1/ADORA3/MCTP1/ABHD2/MITF/RIN3/SPRED1/ARHGAP4/RRAS/OSBPL8/RAP2A/GNA13/PTPRJ/STAT3/RAC1/RGCC/LRP1/DUSP3/SVBP/RHOB/ARHGDIA	41
GO:0050714	positive regulation of protein secretion	21/1068	137/18722	3.22636454098919e-05	0.000290642121255053	HLA-DRB1/TREM2/GLUL/HIF1A/TLR2/TLR4/TGFB1/JAK2/ADAM8/TRPM2/CD33/ADAM9/SERP1/RAC1/ABCG1/LRP1/STX4/TMED10/ARF6/ACSL4/KIF5B	21
GO:0030336	negative regulation of cell migration	39/1068	344/18722	3.42534054837183e-05	0.000308052293316906	APOE/CD74/AIF1/TIMP1/BST2/DUSP1/HMOX1/ARHGDIB/RAP2B/MEF2C/RHOA/CORO1C/CD300A/PTGER4/KLF4/SP100/TGFB1/ENG/VASH1/ADORA3/MCTP1/ABHD2/MITF/RIN3/SPRED1/ARHGAP4/RRAS/OSBPL8/RAP2A/GNA13/PTPRJ/STAT3/RAC1/RGCC/LRP1/DUSP3/SVBP/RHOB/ARHGDIA	39
GO:0030889	negative regulation of B cell proliferation	7/1068	18/18722	3.51691482653187e-05	0.000315237083122358	TYROBP/LYN/MNDA/CD300A/BTK/INPP5D/ATM	7
GO:0150078	positive regulation of neuroinflammatory response	7/1068	18/18722	3.51691482653187e-05	0.000315237083122358	TREM2/CCL3/NUPR1/CTSC/IL18/LRRK2/IL1B	7
GO:0002726	positive regulation of T cell cytokine production	8/1068	24/18722	3.53473888675889e-05	0.000315263653437206	HLA-A/B2M/CD81/IL18/RSAD2/SASH3/DENND1B/IL1B	8
GO:0043302	positive regulation of leukocyte degranulation	8/1068	24/18722	3.53473888675889e-05	0.000315263653437206	ITGB2/HLA-F/SYK/PTAFR/ITGAM/FGR/STX4/LAMP1	8
GO:0051043	regulation of membrane protein ectodomain proteolysis	8/1068	24/18722	3.53473888675889e-05	0.000315263653437206	APOE/TIMP1/TIMP2/TNFRSF1B/ADAM8/ADAM9/IL1B/ROCK1	8
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	17/1068	98/18722	3.60789699629364e-05	0.000321257626930701	CD74/GPX1/PLAUR/CD44/SOD2/HIF1A/TMBIM6/HSPA1A/BID/LRRK2/ARHGEF2/MCL1/GRINA/IVNS1ABP/ZNF385A/HERPUD1/PPIF	17
GO:0032872	regulation of stress-activated MAPK cascade	26/1068	192/18722	3.67758851553486e-05	0.000326923684181649	TREM2/DUSP1/PYCARD/SPI1/CLEC7A/GADD45B/HGF/SDCBP/TAOK3/SIRPA/TLR4/VEGFA/MDFIC/SCIMP/NCF1/RASSF2/MYD88/RAP2A/PTK2B/IL1B/EIF2AK2/DUSP3/PJA2/CDC42/TAOK1/LTBR	26
GO:0034446	substrate adhesion-dependent cell spreading	18/1068	108/18722	3.74776535550483e-05	0.000332614175301054	LIMS1/GBP1/FLNA/RHOA/FERMT3/CORO1C/CIB1/AXL/PARVG/PREX1/MYADM/LPXN/ITGA4/RAC1/CDC42/RCC2/PIK3R1/S100A10	18
GO:0033006	regulation of mast cell activation involved in immune response	9/1068	31/18722	3.98089191983381e-05	0.000352724019694963	CD84/HMOX1/LGALS9/LYN/SYK/CD300A/ADGRE2/FGR/STXBP2	9
GO:0009306	protein secretion	40/1068	359/18722	4.05364557321134e-05	0.000357994623781479	APOE/HLA-DRB1/TREM2/GLUL/PLEK/HIF1A/UCP2/M6PR/TLR2/ALOX5/TLR4/TGFB1/TCIRG1/RSAD2/JAK2/ADAM8/CYB5R4/NR1H3/TRPM2/RHBDF2/CD33/ADAM9/RAB8B/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/ABCA1/STX4/SVBP/CANX/TMED10/ARF6/ACSL4/RAB10/RAB8A/KIF5B/RAB13	40
GO:2000146	negative regulation of cell motility	40/1068	359/18722	4.05364557321134e-05	0.000357994623781479	APOE/CD74/AIF1/TIMP1/BST2/DUSP1/HMOX1/ARHGDIB/RAP2B/MEF2C/RHOA/CORO1C/CD300A/PTGER4/KLF4/WAS/SP100/TGFB1/ENG/VASH1/ADORA3/MCTP1/ABHD2/MITF/RIN3/SPRED1/ARHGAP4/RRAS/OSBPL8/RAP2A/GNA13/PTPRJ/STAT3/RAC1/RGCC/LRP1/DUSP3/SVBP/RHOB/ARHGDIA	40
GO:0006968	cellular defense response	12/1068	54/18722	4.1206054087268e-05	0.000362733917735142	TYROBP/LY96/LSP1/C5AR1/NCF2/MNDA/CLEC5A/TCIRG1/LILRB2/NCF1/SPN/PTK2B	12
GO:0034135	regulation of toll-like receptor 2 signaling pathway	6/1068	13/18722	4.1207541062202e-05	0.000362733917735142	CYBA/TREM2/LYN/TLR1/TNFAIP3/PJA2	6
GO:0010639	negative regulation of organelle organization	39/1068	347/18722	4.15713266724818e-05	0.00036521832393004	TMSB4X/CAPG/GPX1/NUPR1/TSPO/DUSP1/ARRB2/HGF/GMFG/TMSB10/TWF2/CIB1/HSPA1A/CORO1A/WAS/VAT1/LILRB2/ACAA2/MYADM/LRRK2/ARHGEF2/ERCC1/ARAP1/SLC35F6/CAPZA2/CAPZA1/ATM/PRKAR1A/PAK2/APC/GSN/FLII/DYNC1LI1/TAOK1/PIK3R1/CAPZB/RAB7A/PFN1/PPIF	39
GO:0031294	lymphocyte costimulation	11/1068	46/18722	4.16251425531828e-05	0.00036521832393004	LGALS1/CD81/TNFSF13B/CD86/LILRB4/LYN/TNFRSF14/LILRB2/CSK/PTPN6/MAP3K8	11
GO:0035592	establishment of protein localization to extracellular region	40/1068	360/18722	4.31601559296214e-05	0.000378071755513372	APOE/HLA-DRB1/TREM2/GLUL/PLEK/HIF1A/UCP2/M6PR/TLR2/ALOX5/TLR4/TGFB1/TCIRG1/RSAD2/JAK2/ADAM8/CYB5R4/NR1H3/TRPM2/RHBDF2/CD33/ADAM9/RAB8B/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/ABCA1/STX4/SVBP/CANX/TMED10/ARF6/ACSL4/RAB10/RAB8A/KIF5B/RAB13	40
GO:0036294	cellular response to decreased oxygen levels	23/1068	161/18722	4.37338087353584e-05	0.00038247590265153	TREM2/HMOX1/SLC8A1/CYBB/HIF1A/ZFP36L1/TMBIM6/EIF4EBP1/VEGFA/CARD16/ACAA2/IRAK1/ADAM8/PLK3/NAMPT/BNIP3L/MALAT1/RGCC/ERO1A/PGK1/GNB1/BACH1/EGR1	23
GO:0034109	homotypic cell-cell adhesion	16/1068	90/18722	4.45368181084071e-05	0.000388240178534677	LGALS1/CD9/PLAUR/PLEK/ACTB/RAP2B/LYN/FLNA/SYK/FERMT3/JAK1/PTPN6/JAK2/SH2B3/TLN1/CLIC1	16
GO:0045638	negative regulation of myeloid cell differentiation	16/1068	90/18722	4.45368181084071e-05	0.000388240178534677	MAFB/CCL3/C1QC/ZFP36/LILRB4/ZFP36L1/LYN/CIB1/LILRB1/TLR4/LILRB3/GPR137B/INPP5D/PTK2B/NFKBIA/PIK3R1	16
GO:0071456	cellular response to hypoxia	22/1068	151/18722	4.69676908747957e-05	0.000408770419290964	TREM2/HMOX1/SLC8A1/CYBB/HIF1A/ZFP36L1/TMBIM6/EIF4EBP1/VEGFA/CARD16/ACAA2/IRAK1/ADAM8/PLK3/BNIP3L/MALAT1/RGCC/ERO1A/PGK1/GNB1/BACH1/EGR1	22
GO:0110020	regulation of actomyosin structure organization	17/1068	100/18722	4.71315155935082e-05	0.000409535681389002	GPR65/CCDC88A/RHOA/PTGER4/WAS/ARAP1/RAC1/RGCC/TGFBR1/PAK2/ROCK1/PAK1/AKAP13/CDC42/PIK3R1/PFN1/S100A10	17
GO:0033627	cell adhesion mediated by integrin	14/1068	72/18722	4.74229796161972e-05	0.000411405784580386	ITGB2/NCKAP1L/LYN/SYK/FERMT3/CIB1/PLAU/PTPN6/LPXN/ITGA4/ITGA5/ADAM9/ADAM17/WNK1	14
GO:0034599	cellular response to oxidative stress	34/1068	288/18722	4.75503018451772e-05	0.000411848200251326	GPX1/TREM2/AIF1/SOD2/FOS/HMOX1/JUN/CD36/HIF1A/HGF/NR4A2/AXL/HSPA1A/SIRPA/MGST1/ALOX5/SLC25A24/TLR4/KLF4/NCF1/BTK/JAK2/KLF2/TRPM2/MMP2/LRRK2/STAT6/MCL1/TNFAIP3/DAPK1/STX4/SETX/RHOB/PPIF	34
GO:0034314	Arp2/3 complex-mediated actin nucleation	10/1068	39/18722	4.87220379427845e-05	0.000421320699902669	ACTR2/ACTR3/GMFG/ARPC3/WAS/ARPC4/ARPC1B/CYFIP1/ARPC5/BRK1	10
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	8/1068	25/18722	4.93918927917516e-05	0.000425069622813862	LY96/LY86/CD36/CD180/CARD16/SCIMP/LILRA2/TNFAIP3	8
GO:0032753	positive regulation of interleukin-4 production	8/1068	25/18722	4.93918927917516e-05	0.000425069622813862	FCER1G/HLA-E/CD86/HAVCR2/LGALS9/SYK/SASH3/CEBPB	8
GO:1905048	regulation of metallopeptidase activity	8/1068	25/18722	4.93918927917516e-05	0.000425069622813862	TIMP1/SORL1/TIMP2/MBP/STAT3/LRP1/SVBP/PICALM	8
GO:0038066	p38MAPK cascade	12/1068	55/18722	4.99976046537327e-05	0.000429279009182556	TREM2/DUSP1/ZFP36/SPI1/GADD45B/LGALS9/ZFP36L1/HGF/VEGFA/NCF1/IL1B/PJA2	12
GO:0097305	response to alcohol	31/1068	253/18722	5.00401217153128e-05	0.000429279009182556	CYBA/CCL3/HAMP/TSPO/SOD2/CD14/FOS/SPI1/CYBB/ACTR2/RHOA/AHR/RGS19/PTGER4/EIF4EBP1/KLF4/TBXAS1/TGFB1/TGFBR2/KLF2/PTK2B/CDKN1A/STAT3/CPT1A/ADCY7/ABCA1/FOSB/CALM3/TGFBR1/GNB1/RGS2	31
GO:0051492	regulation of stress fiber assembly	16/1068	91/18722	5.12186082652471e-05	0.000438691444760751	GPR65/CCDC88A/RHOA/PTGER4/WAS/ARAP1/RAC1/RGCC/TGFBR1/PAK2/ROCK1/PAK1/CDC42/PIK3R1/PFN1/S100A10	16
GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	11/1068	47/18722	5.15677776743276e-05	0.000440982136815644	HMOX1/JUN/HIF1A/TMBIM6/HSPA1A/VEGFA/KLF2/CEBPB/BACH1/ATF3/EGR1	11
GO:0035456	response to interferon-beta	9/1068	32/18722	5.25990712208551e-05	0.000448380076315536	BST2/IFI16/STAT1/XAF1/IFITM3/MNDA/PLSCR1/OAS1/IRF1	9
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	9/1068	32/18722	5.25990712208551e-05	0.000448380076315536	HLA-DRA/HLA-DRB1/CD86/IL18/CD83/LGALS9/NCKAP1L/SASH3/NFKBIZ	9
GO:0010885	regulation of cholesterol storage	7/1068	19/18722	5.29471262642427e-05	0.000449218071260776	MSR1/TREM2/CD36/LPL/NR1H3/ABCG1/ABCA1	7
GO:0033194	response to hydroperoxide	7/1068	19/18722	5.29471262642427e-05	0.000449218071260776	GPX1/AIF1/CD36/MGST1/JAK2/TRPM2/DAPK1	7
GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	7/1068	19/18722	5.29471262642427e-05	0.000449218071260776	HLA-A/HLA-E/LILRB4/NCKAP1L/LILRB1/RUNX1/IRF1	7
GO:0045861	negative regulation of proteolysis	39/1068	351/18722	5.35455805070175e-05	0.000453513236601144	GPX1/CTSZ/C3/CSTB/TIMP1/CST3/PLAUR/BST2/CD44/SORL1/IFI16/SERPINA1/A2M/TIMP2/ARRB2/HGF/SDCBP/NAIP/KLF4/PRNP/VEGFA/CARD16/RPS6KA1/NR1H3/LRRK2/CSTA/SERPINB8/SERPING1/LRP1/RPS6KA3/PAK2/ROCK1/NR4A1/TMED10/PICALM/FNIP1/HERPUD1/XIAP/CAMLG	39
GO:0001659	temperature homeostasis	24/1068	174/18722	5.36385949628091e-05	0.000453513236601144	FABP5/GPX1/CXCR4/IL18/CD36/ALDH1A1/RB1/UCP2/SYK/TLR4/VEGFA/SCD/JAK2/NR1H3/TRPM2/ACSL1/STAT6/IL1B/STAT3/CEBPB/ADAM17/TLE3/APC/EGR1	24
GO:0050830	defense response to Gram-positive bacterium	17/1068	101/18722	5.37055148606618e-05	0.000453513236601144	HLA-A/ACP5/LYZ/HLA-E/PYCARD/C5AR1/HAVCR2/CD36/RNASE6/TLR2/GBP4/TNFRSF14/GBP2/FGR/MYD88/MR1/ADAM17	17
GO:0038127	ERBB signaling pathway	19/1068	121/18722	5.39237048255696e-05	0.000454644236310583	PLAUR/LGMN/CCDC88A/GRB2/HBEGF/TGFB1/NCF1/RASSF2/RHBDF2/PTPN18/PTK2B/PTPRJ/DUSP3/IQGAP1/RTN4/ADAM17/SHKBP1/NUP62/RAB7A	19
GO:0032507	maintenance of protein location in cell	13/1068	64/18722	5.44821687870326e-05	0.000458636166575394	TMSB4X/SRGN/TSPO/SORL1/CCDC88A/CHCHD10/CD4/TMSB10/TWF2/VPS13C/SP100/GSN/MORC3	13
GO:0045732	positive regulation of protein catabolic process	29/1068	231/18722	5.56761318537048e-05	0.000467957021000921	APOE/LAPTM5/TREM2/CD81/HAMP/NUPR1/SORL1/CTSC/MSN/HSPA1A/TNFRSF1B/OAZ1/TNFSF12/ADAM8/PLK3/LRRK2/PTK2B/GABARAP/ADAM9/GGA1/IL1B/TNFAIP3/LRP1/APC/CEBPA/HERPUD1/PIAS1/SUMO2/RAB7A	29
GO:0031346	positive regulation of cell projection organization	39/1068	353/18722	6.06410994179778e-05	0.000508894824975751	APOE/GRN/CCDC88A/SKIL/LYN/HGF/ACTR2/PLXNC1/ACTR3/FLNA/CORO1C/TWF2/RHOQ/RAP1A/P2RX7/VEGFA/PLXND1/CAMK1D/SCARB2/PTK2B/ARAP1/RAB8B/CYFIP1/RALA/RAC1/SHTN1/LRP1/SETX/IQGAP1/TGFBR1/APC/PAK1/TMEM30A/BRK1/CDC42/RGS2/DBNL/PIK3R1/PFN1	39
GO:0045429	positive regulation of nitric oxide biosynthetic process	10/1068	40/18722	6.16677038991949e-05	0.000515905318201637	AIF1/CLEC7A/CD36/TLR4/KLF4/DDAH2/JAK2/KLF2/PTK2B/IL1B	10
GO:0150077	regulation of neuroinflammatory response	10/1068	40/18722	6.16677038991949e-05	0.000515905318201637	TREM2/CCL3/GRN/NUPR1/CTSC/IL18/PTPRC/TNFRSF1B/LRRK2/IL1B	10
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	11/1068	48/18722	6.34827662651209e-05	0.000530267812332187	PYCARD/SKIL/PTPRC/PEA15/TNFSF12/BID/TNFSF10/STK4/PAK2/LTBR/ATF3	11
GO:0048524	positive regulation of viral process	13/1068	65/18722	6.45890086605711e-05	0.000538674328798209	HLA-DRB1/CD74/LGALS1/LGALS9/CD4/AXL/IFIT1/PABPC1/MDFIC/TRIM38/ADAR/CHMP3/RAB7A	13
GO:0002437	inflammatory response to antigenic stimulus	14/1068	74/18722	6.50620747606671e-05	0.000540115316013169	HLA-DRB1/CD68/GPX1/TREM2/C3/CD81/HLA-E/LYN/SYK/HCK/BTK/NOTCH2/RHBDF2/FGR	14
GO:0007040	lysosome organization	14/1068	74/18722	6.50620747606671e-05	0.000540115316013169	LAPTM5/GRN/PPT1/TPP1/ATP6AP2/CORO1A/LRRK2/SCARB2/ACP2/ABCA1/ARL8B/GAA/CHMP3/RAB7A	14
GO:0080171	lytic vacuole organization	14/1068	74/18722	6.50620747606671e-05	0.000540115316013169	LAPTM5/GRN/PPT1/TPP1/ATP6AP2/CORO1A/LRRK2/SCARB2/ACP2/ABCA1/ARL8B/GAA/CHMP3/RAB7A	14
GO:0045185	maintenance of protein location	16/1068	93/18722	6.72774751433854e-05	0.000557648626534113	TMSB4X/SRGN/TSPO/SORL1/CCDC88A/CHCHD10/CD4/FLNA/TMSB10/TWF2/VPS13C/SP100/NFKBIE/NFKBIA/GSN/MORC3	16
GO:0010875	positive regulation of cholesterol efflux	8/1068	26/18722	6.7792268647538e-05	0.000559492356532083	APOE/TREM2/PLTP/NR1H3/ABCG1/LRP1/NFKBIA/ABCA1	8
GO:1900017	positive regulation of cytokine production involved in inflammatory response	8/1068	26/18722	6.7792268647538e-05	0.000559492356532083	CLEC7A/HIF1A/GPSM3/TLR4/GBP5/MYD88/STAT3/APPL1	8
GO:0010811	positive regulation of cell-substrate adhesion	19/1068	123/18722	6.78109713068907e-05	0.000559492356532083	LIMS1/CD36/FLNA/CIB1/VEGFA/PREX1/MYADM/PLEKHA2/JAK2/RIN2/RRAS/STK4/PTK2B/PTPRJ/RAC1/IQGAP1/ROCK1/CDC42/S100A10	19
GO:0002467	germinal center formation	6/1068	14/18722	6.86316204748283e-05	0.000564986958113224	TNFSF13B/MEF2C/KLHL6/BCL6/TNFAIP3/ADAM17	6
GO:0002335	mature B cell differentiation	9/1068	33/18722	6.86863314533497e-05	0.000564986958113224	LGALS1/SPI1/GPR183/DOCK10/IRF8/NOTCH2/CMTM7/LFNG/PTK2B	9
GO:0030593	neutrophil chemotaxis	17/1068	103/18722	6.93244856657009e-05	0.000568766374672506	CD74/FCER1G/CCL3/CCL3L3/ITGB2/C5AR1/LGALS3/C3AR1/NCKAP1L/CKLF/CCL4/SYK/PREX1/TREM1/CAMK1D/RAC1/BST1	17
GO:0031623	receptor internalization	18/1068	113/18722	6.93566112925331e-05	0.000568766374672506	FCER1G/CD9/CD81/ITGB2/CD63/GRB2/LILRB4/CD36/ARRB2/SDCBP/SYK/LILRB1/VEGFA/RIN3/LRP1/NUMB/PICALM/FLOT1	18
GO:0071692	protein localization to extracellular region	40/1068	368/18722	7.04179720485642e-05	0.000576593895560019	APOE/HLA-DRB1/TREM2/GLUL/PLEK/HIF1A/UCP2/M6PR/TLR2/ALOX5/TLR4/TGFB1/TCIRG1/RSAD2/JAK2/ADAM8/CYB5R4/NR1H3/TRPM2/RHBDF2/CD33/ADAM9/RAB8B/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/ABCA1/STX4/SVBP/CANX/TMED10/ARF6/ACSL4/RAB10/RAB8A/KIF5B/RAB13	40
GO:0030307	positive regulation of cell growth	23/1068	166/18722	7.09506736078245e-05	0.000580075507254274	CYBA/HAMP/CXCR4/CXCL16/SDCBP/RHOA/TWF2/CIB1/HBEGF/VEGFA/RPS6KA1/ITSN2/PTK2B/CYFIP1/SHTN1/LRP1/RPS6KA3/TGFBR1/ADAM17/PAK1/ADAM10/CDC42/DBNL	23
GO:0034205	amyloid-beta formation	12/1068	57/18722	7.25375519861319e-05	0.000592152239814172	APOE/SORL1/IFNGR1/PRNP/APH1B/ABCG1/RTN4/ROCK1/RTN3/TMED10/ADAM10/PICALM	12
GO:0071902	positive regulation of protein serine/threonine kinase activity	26/1068	200/18722	7.39960274719076e-05	0.000603145867429628	CSF1R/TAOK3/RHOA/SYK/CIB1/TLR4/VEGFA/DAZAP2/TGFB1/CSK/IRAK1/ADAM8/LRRK2/ACSL1/STK4/PTK2B/ADAM9/IL1B/RGCC/CALM3/IQGAP1/CAB39/ADAM17/PAK1/AKAP13/TAOK1	26
GO:0051453	regulation of intracellular pH	14/1068	75/18722	7.58515694755613e-05	0.000617337962126891	GRN/PPT1/SLC11A1/ATP6V0D1/ATP6AP2/SLC4A7/DMXL2/TCIRG1/HVCN1/LRRK2/ATP6V0A1/ATP6V0E1/UBE3A/RAB7A	14
GO:0032735	positive regulation of interleukin-12 production	10/1068	41/18722	7.74258023839032e-05	0.000626560109973663	LAPTM5/CLEC7A/LGALS9/CD36/SYK/TLR2/IRF8/TLR4/SCIMP/IRF1	10
GO:1902622	regulation of neutrophil migration	10/1068	41/18722	7.74258023839032e-05	0.000626560109973663	CD74/C5AR1/C3AR1/NCKAP1L/RHOG/CAMK1D/ADAM8/MYD88/RAC1/BST1	10
GO:1904407	positive regulation of nitric oxide metabolic process	10/1068	41/18722	7.74258023839032e-05	0.000626560109973663	AIF1/CLEC7A/CD36/TLR4/KLF4/DDAH2/JAK2/KLF2/PTK2B/IL1B	10
GO:0034104	negative regulation of tissue remodeling	7/1068	20/18722	7.7456327458964e-05	0.000626560109973663	CST3/HAMP/P2RX7/CSK/GPR137B/INPP5D/TNFAIP3	7
GO:0002762	negative regulation of myeloid leukocyte differentiation	11/1068	49/18722	7.76813776079282e-05	0.000626560109973663	MAFB/CCL3/C1QC/LILRB4/LYN/LILRB1/TLR4/LILRB3/GPR137B/INPP5D/PIK3R1	11
GO:0052372	modulation by symbiont of entry into host	11/1068	49/18722	7.76813776079282e-05	0.000626560109973663	HLA-DRB1/CD74/LGALS1/IFITM3/LGALS9/CD4/TRIM22/CIITA/TRIM14/TRIM38/GSN	11
GO:0007041	lysosomal transport	18/1068	114/18722	7.80450188918726e-05	0.000628553614836634	PSAP/LAPTM5/GRN/SORL1/LAMP2/M6PR/HSPA1A/DTX3L/LRRK2/SCARB2/LRP1/IGF2R/ARL8B/RHOB/LAMP1/CHMP3/ZFYVE16/RAB7A	18
GO:0016042	lipid catabolic process	36/1068	320/18722	7.93506458782924e-05	0.000638116371325284	APOE/APOC1/SPP1/LIPA/ASAH1/SORL1/YWHAH/PPT1/PLA2G7/GPCPD1/LPL/NCEH1/HSD17B11/CYP27A1/ACAA2/ABHD2/AOAH/GALC/PLBD2/SRD5A3/MGST2/IL1B/SGPL1/ACAT1/ABHD12/LRP1/CPT1A/DDHD1/HEXA/PLA2G15/ACER3/PLBD1/SCP2/GM2A/HSD17B4/RAB7A	36
GO:0010950	positive regulation of endopeptidase activity	24/1068	179/18722	8.46782969471596e-05	0.000679733334539301	CTSD/LAPTM5/CTSH/LGMN/PYCARD/IFI16/CLEC7A/LGALS9/LYN/RHOA/SYK/MBP/CASP1/BID/JAK2/APH1B/TNFSF10/STAT3/RPS27L/DAPK1/GSN/PICALM/BAX/PSME2	24
GO:0071621	granulocyte chemotaxis	19/1068	125/18722	8.47777120357579e-05	0.000679733334539301	CD74/FCER1G/CCL3/CCL3L3/ITGB2/C5AR1/LGALS3/CSF1R/C3AR1/NCKAP1L/CKLF/CCL4/SYK/PREX1/TREM1/CAMK1D/ADGRE2/RAC1/BST1	19
GO:0007034	vacuolar transport	22/1068	157/18722	8.52619363072506e-05	0.000682601496014724	PSAP/LAPTM5/GRN/SORL1/LAMP2/M6PR/ATP6V0D1/HSPA1A/VPS13C/DTX3L/LRRK2/SCARB2/TMEM50A/LRP1/IGF2R/ARL8B/RHOB/LAMP1/CHMP3/ZFYVE16/RAB7A/CHMP1B	22
GO:0098751	bone cell development	9/1068	34/18722	8.87182371319055e-05	0.000709220159353721	TYROBP/LILRB1/PTPN6/NOTCH2/SH2B3/FLI1/ABI1/ATP6AP1/ZNF385A	9
GO:0070527	platelet aggregation	13/1068	67/18722	8.97680016252667e-05	0.000715492077946734	CD9/PLEK/ACTB/RAP2B/LYN/FLNA/SYK/FERMT3/PTPN6/JAK2/SH2B3/TLN1/CLIC1	13
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	13/1068	67/18722	8.97680016252667e-05	0.000715492077946734	HLA-DRA/HLA-DRB1/CD81/CD86/IL18/CD83/LGALS9/NCKAP1L/TGFBR2/RUNX1/SASH3/BCL6/NFKBIZ	13
GO:0002719	negative regulation of cytokine production involved in immune response	8/1068	27/18722	9.15441399833958e-05	0.0007264296755153	BST2/HMOX1/LILRB4/HLA-F/LILRB1/TGFB1/BCL6/IRAK3	8
GO:0034143	regulation of toll-like receptor 4 signaling pathway	8/1068	27/18722	9.15441399833958e-05	0.0007264296755153	TREM2/LYN/IFI35/NR1H3/LILRA2/TNFAIP3/NINJ1/APPL1	8
GO:0036037	CD8-positive, alpha-beta T cell activation	8/1068	27/18722	9.15441399833958e-05	0.0007264296755153	HLA-A/HLA-E/LILRB4/NCKAP1L/LILRB1/RUNX1/CLEC4A/IRF1	8
GO:0032874	positive regulation of stress-activated MAPK cascade	19/1068	126/18722	9.45906900871175e-05	0.00074950273672553	PYCARD/SPI1/CLEC7A/GADD45B/SDCBP/TAOK3/TLR4/VEGFA/SCIMP/NCF1/RASSF2/MYD88/PTK2B/IL1B/EIF2AK2/PJA2/CDC42/TAOK1/LTBR	19
GO:0032869	cellular response to insulin stimulus	26/1068	203/18722	9.49946103950409e-05	0.000751599586058124	SORL1/STAT1/GRB2/ZFP36L1/GNAI2/UCP2/LPL/PDK4/RHOQ/MYO5A/OSBPL8/RAB8B/SOCS3/IL1B/CYFIP1/SESN3/APC/PAK1/PKM/RAB10/RAB8A/APPL1/PIK3R1/YWHAG/ZNF106/RAB13	26
GO:0022406	membrane docking	15/1068	86/18722	9.58245819238601e-05	0.000757056287058784	PLEK/MSN/VMP1/STX10/STX6/RAB8B/STXBP2/STX4/STX12/ROCK1/STX7/RAB10/RAB8A/RAB7A/RAB13	15
GO:2000404	regulation of T cell migration	10/1068	42/18722	9.64724001192975e-05	0.000761060045385569	AIF1/PYCARD/RHOA/TNFRSF14/ADAM8/ITGA4/SPN/ADAM17/ADAM10/WNK1	10
GO:0002820	negative regulation of adaptive immune response	12/1068	59/18722	0.00010333352457545	0.00081281005628153	HAVCR2/LILRB4/HLA-F/NCKAP1L/PTPRC/SAMSN1/IL4I1/LILRB1/AHR/TNFRSF14/PTPN6/BCL6	12
GO:0043407	negative regulation of MAP kinase activity	12/1068	59/18722	0.00010333352457545	0.00081281005628153	APOE/SORL1/DUSP1/LYN/CD300A/PTPN6/SH2B3/IRAK3/PTPRJ/IL1B/NUP62/RGS2	12
GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	13/1068	68/18722	0.00010526585652501	0.000826804311221181	HLA-DRA/HLA-DRB1/CD86/IL18/LGALS9/GPR183/PTGER4/IL6R/BCL6/SPN/STAT6/STAT3/NFKBIZ	13
GO:0009896	positive regulation of catabolic process	49/1068	492/18722	0.000106421678559214	0.000834667699862676	APOE/LAPTM5/TREM2/CD81/HAMP/NUPR1/MTDH/SORL1/ZFP36L2/ZFP36/HMOX1/CTSC/MSN/HIF1A/ZFP36L1/TRIM22/HSPA1A/TNFRSF1B/PABPC1/OAZ1/P2RX7/TNFSF12/BID/DTX3L/ADAM8/PLK3/TRIM14/LRRK2/BNIP3L/PTK2B/GABARAP/TRIM38/ADAM9/GGA1/BTG2/IL1B/TNFAIP3/LRP1/DAPK1/CPT1A/SESN3/ROCK1/APC/CEBPA/HERPUD1/BAX/PIAS1/SUMO2/RAB7A	49
GO:0001558	regulation of cell growth	43/1068	414/18722	0.000109277834799321	0.000855824668471898	APOE/SPP1/CYBA/HAMP/SGK1/CXCR4/BST2/FBP1/CXCL16/PPT1/RB1/DPYSL2/SDCBP/RHOA/TWF2/CIB1/HSPA1A/HBEGF/VEGFA/TGFB1/RPS6KA1/SGK3/BCL6/ARHGAP4/ITSN2/PTK2B/CDKN1A/PTPRJ/CYFIP1/SHTN1/LRP1/BTG1/RPS6KA3/OGFR/TGFBR1/RTN4/ADAM17/PAK1/ADAM10/LAMTOR2/CDC42/RGS2/DBNL	43
GO:0045655	regulation of monocyte differentiation	7/1068	21/18722	0.00011048310979516	0.000861512804125267	HLA-DRB1/CD74/JUN/ZFP36L1/CD4/IRF7/INPP5D	7
GO:0071605	monocyte chemotactic protein-1 production	7/1068	21/18722	0.00011048310979516	0.000861512804125267	CD84/CLEC7A/LGALS9/SYK/OAS1/OAS3/IL1B	7
GO:0071637	regulation of monocyte chemotactic protein-1 production	7/1068	21/18722	0.00011048310979516	0.000861512804125267	CD84/CLEC7A/LGALS9/SYK/OAS1/OAS3/IL1B	7
GO:0051098	regulation of binding	39/1068	363/18722	0.00011067894094498	0.000861794466578808	APOE/TMSB4X/B2M/CTSZ/PLAUR/SORL1/IFI16/HMOX1/ACTB/JUN/ARRB2/IFIT2/RB1/TMBIM6/IFIT1/KLF4/PARP9/SP100/CARD16/PLXND1/TGFB1/DTX3L/JAK2/ITGA4/LRRK2/STK4/CDKN1A/LRP1/NFKBIA/SUMO3/CALM3/TGFBR1/ROCK1/SKI/CCPG1/CDC42/BAX/FLOT1/S100A10	39
GO:0032814	regulation of natural killer cell activation	9/1068	35/18722	0.000113429371831768	0.00088193788242683	TYROBP/HLA-E/HAVCR2/IL18/HLA-F/AXL/PRDM1/FGR/LAMP1	9
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	11/1068	51/18722	0.000114356823692597	0.000887869669993171	HLA-DRA/HLA-DRB1/CD86/IL18/CD83/LGALS9/NCKAP1L/RUNX1/SASH3/BCL6/NFKBIZ	11
GO:0002765	immune response-inhibiting signal transduction	5/1068	10/18722	0.000118487502264668	0.000914676054678324	LILRB4/LYN/LILRB1/LILRB2/CD33	5
GO:0002887	negative regulation of myeloid leukocyte mediated immunity	5/1068	10/18722	0.000118487502264668	0.000914676054678324	CD84/HMOX1/SPI1/LGALS9/CD300A	5
GO:0070391	response to lipoteichoic acid	5/1068	10/18722	0.000118487502264668	0.000914676054678324	TREM2/CD14/CD36/TLR2/TLR4	5
GO:0071223	cellular response to lipoteichoic acid	5/1068	10/18722	0.000118487502264668	0.000914676054678324	TREM2/CD14/CD36/TLR2/TLR4	5
GO:0006509	membrane protein ectodomain proteolysis	10/1068	43/18722	0.000119340552903528	0.000919945176382053	APOE/TIMP1/TIMP2/TNFRSF1B/ADAM8/ADAM9/IL1B/ROCK1/ADAM17/ADAM10	10
GO:0002313	mature B cell differentiation involved in immune response	8/1068	28/18722	0.000121791090443979	0.000936160575549445	LGALS1/SPI1/GPR183/DOCK10/IRF8/NOTCH2/LFNG/PTK2B	8
GO:0045589	regulation of regulatory T cell differentiation	8/1068	28/18722	0.000121791090443979	0.000936160575549445	HLA-DRA/HLA-DRB1/LGALS9/LILRB4/IL4I1/LILRB2/BCL6/IRF1	8
GO:0002287	alpha-beta T cell activation involved in immune response	13/1068	69/18722	0.000123020358517955	0.000942923088867738	HLA-DRA/HLA-DRB1/CD86/IL18/LGALS9/GPR183/PTGER4/IL6R/BCL6/SPN/STAT6/STAT3/NFKBIZ	13
GO:0002293	alpha-beta T cell differentiation involved in immune response	13/1068	69/18722	0.000123020358517955	0.000942923088867738	HLA-DRA/HLA-DRB1/CD86/IL18/LGALS9/GPR183/PTGER4/IL6R/BCL6/SPN/STAT6/STAT3/NFKBIZ	13
GO:0016049	cell growth	48/1068	482/18722	0.000124950174230754	0.000956356227161914	APOE/SPP1/CYBA/HAMP/SGK1/CXCR4/BST2/ALCAM/FBP1/CXCL16/PPT1/RB1/DPYSL2/SDCBP/RHOA/TWF2/CIB1/HSPA1A/HBEGF/VEGFA/TGFB1/TGFBR2/RPS6KA1/SGK3/ITGA4/BCL6/ARHGAP4/ITSN2/PTK2B/CDKN1A/PTPRJ/CYFIP1/SHTN1/LRP1/BTG1/RPS6KA3/IQGAP1/OGFR/TGFBR1/RTN4/ADAM17/PAK1/ADAM10/LAMTOR2/AKAP13/CDC42/RGS2/DBNL	48
GO:0016197	endosomal transport	28/1068	230/18722	0.000127025851693807	0.000970866141274477	SORL1/CORO1C/WAS/STX10/EHD4/LRRK2/BLOC1S1/STX6/ITSN2/DENND1B/TMEM50A/GGA1/ACAP2/RAB29/ABCA1/BLOC1S2/ARL8B/DENND5A/PICALM/ARF6/ARL4C/CHMP3/RAB10/RAB8A/ZFYVE16/RAB7A/CHMP1B/RAB13	28
GO:0042176	regulation of protein catabolic process	41/1068	391/18722	0.000127348077059607	0.000971952226044753	APOE/LAPTM5/GPX1/TREM2/CD81/TIMP1/CST3/HAMP/NUPR1/SORL1/CTSC/MSN/TIMP2/FLNA/CTSA/SDCBP/HSPA1A/TNFRSF1B/OAZ1/TNFSF12/ADAM8/PLK3/IRAK3/LRRK2/PTK2B/GABARAP/ADAM9/GGA1/IL1B/TNFAIP3/LRP1/ROCK1/APC/CEBPA/HERPUD1/UBE3A/PIAS1/PSME2/CAMLG/SUMO2/RAB7A	41
GO:1901184	regulation of ERBB signaling pathway	14/1068	79/18722	0.000136101554047498	0.00103683001059848	PLAUR/LGMN/CCDC88A/HBEGF/NCF1/RHBDF2/PTPN18/PTPRJ/DUSP3/RTN4/ADAM17/SHKBP1/NUP62/RAB7A	14
GO:0051100	negative regulation of binding	22/1068	162/18722	0.000136232853505249	0.00103683001059848	TMSB4X/B2M/CTSZ/SORL1/IFI16/HMOX1/ACTB/JUN/ARRB2/IFIT2/TMBIM6/IFIT1/SP100/CARD16/JAK2/ITGA4/LRRK2/CDKN1A/NFKBIA/SUMO3/ROCK1/BAX	22
GO:0016358	dendrite development	29/1068	243/18722	0.000137910285004638	0.00104811816603525	APOE/YWHAH/MEF2A/LST1/PHACTR1/MEF2C/ACTR2/DOCK10/RHOA/SDC2/PREX1/ABI3/CAMK1D/TANC2/LRRK2/RAP2A/ABI1/HPRT1/CYFIP1/IQGAP1/PAK2/CFL1/ADAM10/PICALM/ARF6/ACSL4/CDC42/UBE3A/DBNL	29
GO:0015918	sterol transport	19/1068	130/18722	0.000144610139788894	0.00109749130000123	APOE/APOC1/MSR1/NPC2/TREM2/TSPO/CD36/SOAT1/PLTP/OSBPL1A/NR1H3/OSBPL8/ABCG1/LRP1/NFKBIA/ABCA1/STX12/ARL8B/SCP2	19
GO:0150076	neuroinflammatory response	10/1068	44/18722	0.000146623894008622	0.00111121142144736	TREM2/CCL3/GRN/NUPR1/CTSC/IL18/PTPRC/TNFRSF1B/LRRK2/IL1B	10
GO:0010952	positive regulation of peptidase activity	25/1068	197/18722	0.000148843588997309	0.00112645162164023	CTSD/LAPTM5/GRN/CTSH/LGMN/PYCARD/IFI16/CLEC7A/LGALS9/LYN/RHOA/SYK/MBP/CASP1/BID/JAK2/APH1B/TNFSF10/STAT3/RPS27L/DAPK1/GSN/PICALM/BAX/PSME2	25
GO:0002220	innate immune response activating cell surface receptor signaling pathway	7/1068	22/18722	0.000154097323825143	0.00116457865456648	TYROBP/CLEC7A/LYN/SYK/LILRA2/PAK2/PAK1	7
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	8/1068	29/18722	0.000159833579971594	0.00120210567801871	HLA-DRB1/GPX1/TREM2/LYN/SYK/HCK/RHBDF2/FGR	8
GO:0010592	positive regulation of lamellipodium assembly	8/1068	29/18722	0.000159833579971594	0.00120210567801871	ACTR2/ACTR3/TWF2/CYFIP1/RAC1/BRK1/CDC42/PIK3R1	8
GO:1903902	positive regulation of viral life cycle	8/1068	29/18722	0.000159833579971594	0.00120210567801871	HLA-DRB1/CD74/LGALS1/LGALS9/CD4/AXL/TRIM38/CHMP3	8
GO:0048259	regulation of receptor-mediated endocytosis	17/1068	110/18722	0.000159954017201155	0.00120210567801871	APOC1/B2M/C3/PPT1/CD63/BMP2K/ARRB2/SDCBP/SYK/VEGFA/RIN3/RAC1/NUMB/SMAP1/PICALM/ARF6/FLOT1	17
GO:0031099	regeneration	25/1068	198/18722	0.000161333290504795	0.00121078502860066	SPP1/GPX1/CD9/CD81/GRN/HAMP/TSPO/C5AR1/HMOX1/LCP1/HGF/FLNA/UCP2/AXL/RAP1A/KLF4/TGFBR2/RUNX1/JAK2/CDKN1A/NINJ1/LRP1/CPT1A/CEBPB/IGF2R	25
GO:0031667	response to nutrient levels	47/1068	474/18722	0.000161938453972676	0.00121363874671744	APOE/SPP1/CD68/CYBA/GLUL/HAMP/TSPO/SORL1/SOD2/IFI16/STAT1/ZFP36/HMOX1/SLC8A1/CYBB/JUN/GNAI2/UPP1/LAMP2/UCP2/LPL/USF2/PDK4/EIF4EBP1/KYNU/C2/TGFBR2/RRAGD/NAMPT/LRRK2/PRKAG2/ACSL1/GABARAP/CDKN1A/ERCC1/ACAT1/EIF2AK2/CPT1A/LDHA/SESN3/ABCA1/MAX/KLF10/FNIP1/ACSL4/ATF3/PLEC	47
GO:2001242	regulation of intrinsic apoptotic signaling pathway	22/1068	164/18722	0.000163211654126413	0.00122148416874636	CD74/GPX1/TREM2/NUPR1/PLAUR/CD44/SOD2/PYCARD/SKIL/HIF1A/TMBIM6/HSPA1A/BID/LRRK2/ARHGEF2/MCL1/GRINA/IVNS1ABP/ZNF385A/HERPUD1/BAX/PPIF	22
GO:0045806	negative regulation of endocytosis	11/1068	53/18722	0.000164847187920173	0.00122892541268115	APOC1/LGALS3/SDCBP/CD300A/LILRB1/MCTP1/NR1H3/RIN3/RAC1/PICALM/ARF6	11
GO:0002830	positive regulation of type 2 immune response	6/1068	16/18722	0.000165800166870252	0.00122892541268115	CD74/CD81/CD86/IL18/RSAD2/DENND1B	6
GO:0034138	toll-like receptor 3 signaling pathway	6/1068	16/18722	0.000165800166870252	0.00122892541268115	HAVCR2/OAS1/UNC93B1/SCIMP/TNFAIP3/FLOT1	6
GO:0045779	negative regulation of bone resorption	6/1068	16/18722	0.000165800166870252	0.00122892541268115	HAMP/P2RX7/CSK/GPR137B/INPP5D/TNFAIP3	6
GO:0051014	actin filament severing	6/1068	16/18722	0.000165800166870252	0.00122892541268115	CAPG/GMFG/FMNL1/GSN/FLII/CFL1	6
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	6/1068	16/18722	0.000165800166870252	0.00122892541268115	STAT1/TLR2/TLR4/JAK2/NAMPT/LRRK2	6
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	6/1068	16/18722	0.000165800166870252	0.00122892541268115	SLC15A3/HSPA1A/TLR4/LACC1/TNFAIP3/NFKBIA	6
GO:0010634	positive regulation of epithelial cell migration	23/1068	176/18722	0.000174093549374991	0.0012886266014094	TMSB4X/GRN/CTSH/LGMN/HMOX1/HIF1A/CIB1/HBEGF/GLIPR2/VEGFA/TGFB1/TGFBR2/RIN2/STAT5A/RRAS/PTK2B/ADAM9/RAC1/RTN4/ADAM17/RHOB/ARF6/PFN1	23
GO:0032570	response to progesterone	9/1068	37/18722	0.000180296410752531	0.00133088841644413	TXNIP/TSPO/FOS/TLR2/TGFB1/ABHD2/NR1H3/FOSB/UBE3A	9
GO:1902745	positive regulation of lamellipodium organization	9/1068	37/18722	0.000180296410752531	0.00133088841644413	ACTR2/ACTR3/CORO1C/TWF2/CYFIP1/RAC1/BRK1/CDC42/PIK3R1	9
GO:0070228	regulation of lymphocyte apoptotic process	11/1068	54/18722	0.000196476315179753	0.00144834179878408	CD74/LGALS3/LGALS9/HIF1A/LYN/BTK/ADAM8/BCL6/TSC22D3/FNIP1/BAX	11
GO:0032233	positive regulation of actin filament bundle assembly	12/1068	63/18722	0.000199572985470641	0.00146916211405126	GPR65/PLEK/CCDC88A/FLNA/RHOA/RAC1/RGCC/TGFBR1/PAK1/CDC42/PFN1/S100A10	12
GO:0002357	defense response to tumor cell	5/1068	11/18722	0.000207018329361252	0.00151656799138166	LAPTM5/SPI1/KLF4/ABI3/DAPK1	5
GO:0045657	positive regulation of monocyte differentiation	5/1068	11/18722	0.000207018329361252	0.00151656799138166	HLA-DRB1/CD74/JUN/ZFP36L1/CD4	5
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	5/1068	11/18722	0.000207018329361252	0.00151656799138166	CD74/LPL/MBP/TLR4/LRP1	5
GO:0043032	positive regulation of macrophage activation	8/1068	30/18722	0.000207136880957799	0.00151656799138166	TREM2/CCL3/HAMP/HAVCR2/CTSC/TLR4/LRRK2/CEBPA	8
GO:0010720	positive regulation of cell development	33/1068	298/18722	0.000208093762697643	0.00152150940855892	TYROBP/CXCR4/TSPO/LIMS1/ID2/CLEC7A/SKIL/HIF1A/LYN/ACTR2/PLXNC1/FLNA/TWF2/TLR2/CIB1/TNFRSF1B/VEGFA/PREX1/PLXND1/TGFB1/MYADM/IL1B/CYFIP1/RAC1/SHTN1/ATP6AP1/LRP1/NUMB/PAK1/CDC42/SPEN/DBNL/S100A10	33
GO:0030168	platelet activation	18/1068	123/18722	0.00021066358878479	0.00153614143260151	APOE/FCER1G/CD9/PLEK/ACTB/RAP2B/LYN/FLNA/PLSCR1/SYK/FERMT3/AXL/TLR4/PTPN6/JAK2/SH2B3/TLN1/CLIC1	18
GO:0006622	protein targeting to lysosome	7/1068	23/18722	0.00021066431803653	0.00153614143260151	LAPTM5/SORL1/LAMP2/M6PR/SCARB2/ZFYVE16/RAB7A	7
GO:0016485	protein processing	27/1068	225/18722	0.000211043325928422	0.00153682832214543	CTSZ/CTSS/SRGN/CTSH/LGMN/PYCARD/IFI16/CPM/ATP6AP2/CASP1/PRNP/CARD16/PLAU/RUNX1/ADAM8/APH1B/LRRK2/SPCS3/PGK1/HM13/PRKACB/ADAM17/GSN/FAM111A/ADAM10/XIAP/SEC11A	27
GO:0007254	JNK cascade	22/1068	167/18722	0.000212540642490759	0.00154564596614574	PYCARD/GADD45B/SDCBP/TAOK3/TLR7/SIRPA/PTGER4/TLR4/MDFIC/NCF1/IRAK1/RASSF2/LRRK2/MYD88/RAP2A/PTK2B/IL1B/DUSP3/PJA2/CDC42/TAOK1/LTBR	22
GO:0032147	activation of protein kinase activity	19/1068	134/18722	0.000216547018495271	0.00157205098698398	CCDC88A/CD86/IL18/SLC11A1/NCKAP1L/CD300A/PRNP/VEGFA/TGFBR2/IRAK1/JAK2/IL6R/PRKAG2/OSBPL8/PTK2B/RGCC/CAB39/PPP2R3C/WNK1	19
GO:0031331	positive regulation of cellular catabolic process	43/1068	427/18722	0.000216754250243899	0.00157205098698398	APOE/LAPTM5/TREM2/CD81/HAMP/NUPR1/MTDH/ZFP36L2/ZFP36/HMOX1/CTSC/MSN/HIF1A/ZFP36L1/TRIM22/HSPA1A/TNFRSF1B/PABPC1/P2RX7/BID/DTX3L/ADAM8/PLK3/TRIM14/LRRK2/BNIP3L/PTK2B/GABARAP/TRIM38/ADAM9/BTG2/IL1B/TNFAIP3/LRP1/DAPK1/CPT1A/SESN3/ROCK1/CEBPA/HERPUD1/BAX/PIAS1/SUMO2	43
GO:0032386	regulation of intracellular transport	36/1068	337/18722	0.000223858682167151	0.00162100918445844	CD81/IFI27/ITGB2/SORL1/LCP1/MSN/CD36/FLNA/NUP214/CIB1/MX2/OAZ1/PRNP/SP100/TGFB1/MDFIC/ITGAM/JAK2/PLK3/LRRK2/BNIP3L/RAB29/IL1B/NUCB1/PAK1/TMEM30A/NUP62/HCLS1/UHMK1/LAMP1/CDC42/CHMP3/UBE2D3/SCP2/KIF5B/PIK3R1	36
GO:0032373	positive regulation of sterol transport	9/1068	38/18722	0.000224405830391114	0.00162100918445844	APOE/TREM2/PLTP/NR1H3/ABCG1/LRP1/NFKBIA/ABCA1/SCP2	9
GO:0032376	positive regulation of cholesterol transport	9/1068	38/18722	0.000224405830391114	0.00162100918445844	APOE/TREM2/PLTP/NR1H3/ABCG1/LRP1/NFKBIA/ABCA1/SCP2	9
GO:0044242	cellular lipid catabolic process	26/1068	214/18722	0.000225065037855727	0.00162359751907687	APOC1/ASAH1/SORL1/PPT1/PLA2G7/GPCPD1/LPL/ACAA2/ABHD2/AOAH/GALC/PLBD2/SRD5A3/MGST2/SGPL1/ACAT1/ABHD12/LRP1/CPT1A/HEXA/PLA2G15/ACER3/PLBD1/SCP2/GM2A/HSD17B4	26
GO:0071241	cellular response to inorganic substance	27/1068	226/18722	0.000226966602605833	0.00163512922251145	B2M/TSPO/FBP1/LGMN/FOS/ALOX5AP/MEF2A/HMOX1/CYBB/JUN/JUNB/MEF2C/SLC25A24/PRNP/HVCN1/NCF1/TRPM2/LRRK2/MT1X/MCOLN1/ADCY7/FOSB/IQGAP1/CEBPA/WNK1/UBE2D3/PPIF	27
GO:0048247	lymphocyte chemotaxis	12/1068	64/18722	0.000233055481628396	0.001672587735651	CCL3/CCL3L3/CXCL16/CKLF/GPR183/CCL4/ADAM8/PTK2B/ADAM17/ADAM10/WNK1/PLEC	12
GO:0061614	pri-miRNA transcription by RNA polymerase II	11/1068	55/18722	0.000233095992811259	0.001672587735651	FOS/SPI1/JUN/LILRB4/HIF1A/KLF4/TGFB1/STAT3/DDX5/NR3C1/EGR1	11
GO:1902991	regulation of amyloid precursor protein catabolic process	11/1068	55/18722	0.000233095992811259	0.001672587735651	APOE/SORL1/LYN/IFNGR1/PRNP/ABCG1/RTN4/ROCK1/RTN3/TMED10/PICALM	11
GO:0048678	response to axon injury	14/1068	83/18722	0.000233979465078996	0.00167669746821549	SPP1/LGALS1/TYROBP/TREM2/AIF1/GRN/TSPO/LYN/FLNA/KLF4/JAK2/LRP1/MAX/BAX	14
GO:0016045	detection of bacterium	6/1068	17/18722	0.000243906938906797	0.0017432077382001	HLA-DRB1/HLA-A/HLA-B/TLR2/NAIP/TLR1	6
GO:0090713	immunological memory process	6/1068	17/18722	0.000243906938906797	0.0017432077382001	HLA-DRA/HLA-DRB1/CD81/FGL2/TNFRSF14/BCL6	6
GO:1903829	positive regulation of cellular protein localization	31/1068	276/18722	0.00024894321655622	0.00177684867266847	TYROBP/TREM2/CD81/ITGB2/SORL1/CCDC88A/LGALS3/MSN/FLNA/CIB1/RHOG/PARP9/PRNP/TGFB1/ITGAM/DTX3L/JAK2/GPR137B/ATP2C1/LRP1/STX4/IQGAP1/RTN4/APC/PAK1/NUP62/HCLS1/ARF6/UBE2D3/KIF5B/PIK3R1	31
GO:0031214	biomineral tissue development	22/1068	169/18722	0.000252321710739381	0.00179858381922021	SPP1/GPNMB/CCL3/SRGN/ISG15/SNX10/SLC8A1/BMP2K/HIF1A/MEF2C/ALOX5/P2RX7/CCR1/TGFB1/TCIRG1/FAM20C/FGR/PTK2B/CEBPB/FBXL15/ROCK1/KLF10	22
GO:0040013	negative regulation of locomotion	40/1068	391/18722	0.00025680176778459	0.00182640903339786	APOE/CD74/AIF1/TIMP1/BST2/DUSP1/HMOX1/ARHGDIB/RAP2B/MEF2C/RHOA/CORO1C/CD300A/PTGER4/KLF4/WAS/SP100/TGFB1/ENG/VASH1/ADORA3/MCTP1/ABHD2/MITF/RIN3/SPRED1/ARHGAP4/RRAS/OSBPL8/RAP2A/GNA13/PTPRJ/STAT3/RAC1/RGCC/LRP1/DUSP3/SVBP/RHOB/ARHGDIA	40
GO:0046394	carboxylic acid biosynthetic process	34/1068	314/18722	0.000256902234312264	0.00182640903339786	APOC1/CD74/FABP5/GLUL/SDS/ALOX5AP/LTA4H/ALDH1A1/LPL/PDK4/SYK/DPYD/ALOX5/TBXAS1/SDSL/CYP27A1/KYNU/SCD/OSBPL1A/GLS/ABHD2/LPGAT1/PTGS1/NR1H3/LTC4S/PRKAG2/GPX4/MGST2/IL1B/AKR1A1/QKI/HACD4/SLC1A3/SCP2	34
GO:1903531	negative regulation of secretion by cell	20/1068	147/18722	0.000262927959137199	0.00186678850987412	APOE/CD84/HMOX1/SPI1/LGALS9/HLA-F/NCKAP1L/GNAI2/UCP2/CD300A/LILRB1/TNFRSF1B/RAP1A/RSAD2/NR1H3/RHBDF2/SLC30A1/IL1B/TNFRSF1A/RAB7A	20
GO:1905952	regulation of lipid localization	23/1068	181/18722	0.000264065725020065	0.00187240295953781	APOE/APOC1/SPP1/MSR1/TREM2/C3/TSPO/PLIN2/CD36/LPL/RETN/SYK/PLTP/NR1H3/OSBPL8/ACSL1/IL1B/ABCG1/LRP1/NFKBIA/ABCA1/TMEM30A/SCP2	23
GO:0002828	regulation of type 2 immune response	8/1068	31/18722	0.000265337911135001	0.0018764919639377	CD74/CD81/CD86/IL18/RSAD2/BCL6/DENND1B/STAT6	8
GO:0045066	regulatory T cell differentiation	8/1068	31/18722	0.000265337911135001	0.0018764919639377	HLA-DRA/HLA-DRB1/LGALS9/LILRB4/IL4I1/LILRB2/BCL6/IRF1	8
GO:0032370	positive regulation of lipid transport	14/1068	84/18722	0.000266278022102653	0.00187821726439989	APOE/SPP1/TREM2/RETN/PLTP/NR1H3/ACSL1/IL1B/ABCG1/LRP1/NFKBIA/ABCA1/TMEM30A/SCP2	14
GO:0097061	dendritic spine organization	14/1068	84/18722	0.000266278022102653	0.00187821726439989	APOE/TREM2/LGMN/ACTR2/DOCK10/PRNP/ABI3/TANC2/LRRK2/CFL1/ADAM10/CDC42/UBE3A/DBNL	14
GO:0046456	icosanoid biosynthetic process	11/1068	56/18722	0.000275319034983118	0.00193945367202207	CD74/FABP5/ALOX5AP/LTA4H/SYK/ALOX5/TBXAS1/PTGS1/LTC4S/MGST2/IL1B	11
GO:0002701	negative regulation of production of molecular mediator of immune response	9/1068	39/18722	0.000277110968125613	0.00194953166102452	BST2/HMOX1/LILRB4/HLA-F/TMBIM6/LILRB1/TGFB1/BCL6/IRAK3	9
GO:1903077	negative regulation of protein localization to plasma membrane	7/1068	24/18722	0.000282853641811976	0.00198734147293935	GBP1/RHOQ/TGFB1/ABI3/CSK/NUMB/PICALM	7
GO:0016053	organic acid biosynthetic process	34/1068	316/18722	0.000289214157599779	0.00202938828921769	APOC1/CD74/FABP5/GLUL/SDS/ALOX5AP/LTA4H/ALDH1A1/LPL/PDK4/SYK/DPYD/ALOX5/TBXAS1/SDSL/CYP27A1/KYNU/SCD/OSBPL1A/GLS/ABHD2/LPGAT1/PTGS1/NR1H3/LTC4S/PRKAG2/GPX4/MGST2/IL1B/AKR1A1/QKI/HACD4/SLC1A3/SCP2	34
GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	16/1068	105/18722	0.000291220322571526	0.00204081150726747	CCDC88A/ACTR2/ACTR3/TWF2/RHOQ/P2RX7/ARAP1/CYFIP1/RALA/RAC1/TGFBR1/APC/BRK1/CDC42/PIK3R1/PFN1	16
GO:1901654	response to ketone	24/1068	194/18722	0.000294604487079161	0.00206184930256699	SPP1/CYBA/TXNIP/TSPO/FOS/DUSP1/CYBB/MSN/TLR2/AHR/PTGER4/KLF4/TGFB1/DDIT4/PTAFR/ABHD2/KLF2/NR1H3/CDKN1A/FOSB/CALM3/GNB1/UBE3A/NR3C1	24
GO:0051048	negative regulation of secretion	22/1068	171/18722	0.00029850769957632	0.00208149233805746	APOE/CD74/CD84/HMOX1/SPI1/LGALS9/HLA-F/NCKAP1L/GNAI2/UCP2/CD300A/LILRB1/TNFRSF1B/RAP1A/RSAD2/NR1H3/RHBDF2/SLC30A1/IL1B/TNFRSF1A/WNK1/RAB7A	22
GO:0110148	biomineralization	22/1068	171/18722	0.00029850769957632	0.00208149233805746	SPP1/GPNMB/CCL3/SRGN/ISG15/SNX10/SLC8A1/BMP2K/HIF1A/MEF2C/ALOX5/P2RX7/CCR1/TGFB1/TCIRG1/FAM20C/FGR/PTK2B/CEBPB/FBXL15/ROCK1/KLF10	22
GO:0055074	calcium ion homeostasis	45/1068	460/18722	0.000298568396897049	0.00208149233805746	APOE/CYBA/CCL3/CXCR4/FPR3/GPR65/SNX10/C5AR1/SLC8A1/C3AR1/CD36/PTPRC/LYN/RMDN3/LPAR6/CD52/TMBIM6/FPR1/CORO1A/PTGER4/P2RX7/PRNP/CCR1/TCIRG1/PTPN6/CCRL2/JAK2/TRPM2/ATP1B1/GNA15/ATP2C1/PTK2B/GNA13/MCOLN1/SLC30A1/GRINA/LRP1/ERO1A/CALM3/TMCO1/GNB1/GSTO1/HERPUD1/BAX/MICU1	45
GO:0007044	cell-substrate junction assembly	15/1068	95/18722	0.000300624393798236	0.00209042426409186	LIMS1/RHOA/CORO1C/VEGFA/TLN1/PTK2B/PTPRJ/RAC1/LRP1/DUSP3/IQGAP1/ROCK1/RCC2/PLEC/S100A10	15
GO:0042982	amyloid precursor protein metabolic process	15/1068	95/18722	0.000300624393798236	0.00209042426409186	APOE/SORL1/SOAT1/LYN/IFNGR1/PRNP/APH1B/ABCG1/RTN4/ROCK1/ADAM17/RTN3/TMED10/ADAM10/PICALM	15
GO:0007163	establishment or maintenance of cell polarity	26/1068	218/18722	0.000302024481394819	0.00209745701622451	ACTB/MSN/NCKAP1L/ACTR2/ACTR3/CCL4/RHOA/PARVG/DOCK2/RHOG/TCIRG1/CYTH1/SPN/PTK2B/CAP1/RAC1/SHTN1/ROCK1/GSN/PAK1/RHOB/ARPC5/ARF6/CDC42/SDCCAG8/RAB10	26
GO:0033628	regulation of cell adhesion mediated by integrin	10/1068	48/18722	0.000314092282536943	0.0021674512358423	NCKAP1L/LYN/SYK/FERMT3/CIB1/PLAU/PTPN6/LPXN/ADAM9/WNK1	10
GO:1902003	regulation of amyloid-beta formation	10/1068	48/18722	0.000314092282536943	0.0021674512358423	APOE/SORL1/IFNGR1/PRNP/ABCG1/RTN4/ROCK1/RTN3/TMED10/PICALM	10
GO:1905710	positive regulation of membrane permeability	10/1068	48/18722	0.000314092282536943	0.0021674512358423	LAPTM5/CHCHD10/HSPA1A/ACAA2/BID/BNIP3L/SLC35F6/BLOC1S2/BAX/PPIF	10
GO:0042093	T-helper cell differentiation	12/1068	66/18722	0.000314513402087568	0.0021674512358423	HLA-DRA/HLA-DRB1/CD86/IL18/GPR183/PTGER4/IL6R/BCL6/SPN/STAT6/STAT3/NFKBIZ	12
GO:0051893	regulation of focal adhesion assembly	12/1068	66/18722	0.000314513402087568	0.0021674512358423	LIMS1/RHOA/CORO1C/VEGFA/PTPRJ/RAC1/LRP1/DUSP3/IQGAP1/ROCK1/RCC2/S100A10	12
GO:0090109	regulation of cell-substrate junction assembly	12/1068	66/18722	0.000314513402087568	0.0021674512358423	LIMS1/RHOA/CORO1C/VEGFA/PTPRJ/RAC1/LRP1/DUSP3/IQGAP1/ROCK1/RCC2/S100A10	12
GO:0006874	cellular calcium ion homeostasis	44/1068	448/18722	0.000318455551000611	0.00219181907295829	APOE/CYBA/CCL3/CXCR4/FPR3/GPR65/C5AR1/SLC8A1/C3AR1/CD36/PTPRC/LYN/RMDN3/LPAR6/CD52/TMBIM6/FPR1/CORO1A/PTGER4/P2RX7/PRNP/CCR1/TCIRG1/PTPN6/CCRL2/JAK2/TRPM2/ATP1B1/GNA15/ATP2C1/PTK2B/GNA13/MCOLN1/SLC30A1/GRINA/LRP1/ERO1A/CALM3/TMCO1/GNB1/GSTO1/HERPUD1/BAX/MICU1	44
GO:1900024	regulation of substrate adhesion-dependent cell spreading	11/1068	57/18722	0.000323810259178049	0.00222583459684682	LIMS1/GBP1/FLNA/CORO1C/CIB1/PREX1/MYADM/RAC1/CDC42/RCC2/S100A10	11
GO:0034764	positive regulation of transmembrane transport	26/1068	219/18722	0.000324568330173261	0.00222820700968819	TMSB4X/TREM2/C3/CTSS/MEF2A/IFNGR2/VMP1/FLNA/RHOQ/RAP1A/P2RX7/PTAFR/CREBL2/KCNE3/ATP1B1/GLRX/OSBPL8/ACSL1/CALM3/GSTO1/BAX/WNK1/APPL1/KIF5B/ATP1B3/PIK3R1	26
GO:0006816	calcium ion transport	42/1068	422/18722	0.000327309724187549	0.00224417188273954	CYBA/CCL3/CXCR4/TSPO/CD84/LGALS3/SLC8A1/PTPRC/ARRB2/GNAI2/LYN/VMP1/CD4/HOMER3/CCL4/RHOA/TMBIM6/CORO1A/LILRB1/P2RX7/PRNP/CCR1/LILRB2/KCNE3/PTPN6/TRPM2/ORAI2/ATP1B1/LILRA2/CD33/ATP2C1/PTK2B/MCOLN1/SLC30A1/ERO1A/CALM3/ORAI3/TMCO1/GSTO1/SARAF/BAX/MICU1	42
GO:0050708	regulation of protein secretion	30/1068	268/18722	0.000329510143850694	0.0022563917972314	APOE/HLA-DRB1/TREM2/GLUL/HIF1A/UCP2/TLR2/ALOX5/TLR4/TGFB1/TCIRG1/RSAD2/JAK2/ADAM8/NR1H3/TRPM2/RHBDF2/CD33/ADAM9/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/STX4/TMED10/ARF6/ACSL4/KIF5B	30
GO:0031100	animal organ regeneration	13/1068	76/18722	0.000335872144445175	0.0022842476310839	HAMP/C5AR1/HMOX1/LCP1/HGF/UCP2/AXL/RAP1A/TGFBR2/CDKN1A/CPT1A/CEBPB/IGF2R	13
GO:0010743	regulation of macrophage derived foam cell differentiation	8/1068	32/18722	0.00033625085777305	0.0022842476310839	MSR1/IL18/CD36/LPL/NR1H3/ABCG1/NFKBIA/ABCA1	8
GO:0097345	mitochondrial outer membrane permeabilization	8/1068	32/18722	0.00033625085777305	0.0022842476310839	CHCHD10/HSPA1A/ACAA2/BID/BNIP3L/SLC35F6/BLOC1S2/BAX	8
GO:0071559	response to transforming growth factor beta	29/1068	256/18722	0.000337008647031437	0.0022842476310839	LIMS1/ZEB2/ZFP36L2/FOS/SPI1/SKIL/JUN/MEF2C/ZFP36L1/ARRB2/SDCBP/HSPA1A/ZYX/ZMIZ1/TGFB1/ENG/TGFBR2/LPXN/C20orf27/SPRED1/ADAM9/STAT3/HTRA1/TGFBR1/ROCK1/ADAM17/SKI/NR3C1/APPL1	29
GO:0002424	T cell mediated immune response to tumor cell	5/1068	12/18722	0.000338234591778361	0.0022842476310839	HLA-DRB1/HLA-A/IL4I1/AHR/MR1	5
GO:0032490	detection of molecule of bacterial origin	5/1068	12/18722	0.000338234591778361	0.0022842476310839	TREM2/LY96/TLR2/TLR4/TLR1	5
GO:0048548	regulation of pinocytosis	5/1068	12/18722	0.000338234591778361	0.0022842476310839	PPT1/AXL/NR1H3/CDC42/APPL1	5
GO:0060009	Sertoli cell development	5/1068	12/18722	0.000338234591778361	0.0022842476310839	FLNA/FNDC3A/ARID4A/HSD17B4/RAB13	5
GO:0060907	positive regulation of macrophage cytokine production	5/1068	12/18722	0.000338234591778361	0.0022842476310839	CD74/LAPTM5/CD36/LILRB1/TLR4	5
GO:0140052	cellular response to oxidised low-density lipoprotein particle stimulus	5/1068	12/18722	0.000338234591778361	0.0022842476310839	CD68/TREM2/CD36/TLR4/MYD88	5
GO:1905245	regulation of aspartic-type peptidase activity	5/1068	12/18722	0.000338234591778361	0.0022842476310839	GRN/SORL1/LYN/TMED10/PICALM	5
GO:0010543	regulation of platelet activation	9/1068	40/18722	0.000339659012578445	0.00228813986501035	APOE/FCER1G/CD9/PLEK/LYN/SYK/TLR4/JAK2/SH2B3	9
GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	9/1068	40/18722	0.000339659012578445	0.00228813986501035	CHCHD10/HSPA1A/ACAA2/BID/BNIP3L/SLC35F6/BLOC1S2/BAX/PPIF	9
GO:0030301	cholesterol transport	17/1068	117/18722	0.000340644475172294	0.00229191719205698	APOE/APOC1/MSR1/NPC2/TREM2/TSPO/CD36/SOAT1/PLTP/NR1H3/ABCG1/LRP1/NFKBIA/ABCA1/STX12/ARL8B/SCP2	17
GO:0060761	negative regulation of response to cytokine stimulus	14/1068	86/18722	0.000342483169843517	0.00230141866061721	TREM2/ISG15/SAMHD1/PTPRC/OAS1/KLF4/STAT2/CARD16/NR1H3/OAS3/SH2B3/IRAK3/PARP14/ADAR	14
GO:0031032	actomyosin structure organization	24/1068	196/18722	0.000343464568603905	0.0023051428012272	GPR65/MEF2A/CCDC88A/PHACTR1/RHOA/PTGER4/ZYX/WAS/PTK2B/ARAP1/RAC1/RGCC/PRKAR1A/TGFBR1/PAK2/ROCK1/PAK1/FLII/AKAP13/CDC42/PIK3R1/PLEC/PFN1/S100A10	24
GO:0007204	positive regulation of cytosolic calcium ion concentration	34/1068	319/18722	0.000344490190090372	0.00230915411891633	CYBA/CCL3/CXCR4/FPR3/GPR65/C5AR1/SLC8A1/C3AR1/CD36/PTPRC/LYN/LPAR6/CD52/TMBIM6/FPR1/CORO1A/PTGER4/P2RX7/PRNP/CCR1/PTPN6/CCRL2/JAK2/TRPM2/GNA15/PTK2B/GNA13/MCOLN1/LRP1/ERO1A/CALM3/GNB1/GSTO1/BAX	34
GO:0002223	stimulatory C-type lectin receptor signaling pathway	6/1068	18/18722	0.000348275834227536	0.00231076175883882	TYROBP/CLEC7A/LYN/SYK/PAK2/PAK1	6
GO:0002643	regulation of tolerance induction	6/1068	18/18722	0.000348275834227536	0.00231076175883882	HLA-B/HAVCR2/LILRB4/TGFBR2/LILRB2/IRAK3	6
GO:0034162	toll-like receptor 9 signaling pathway	6/1068	18/18722	0.000348275834227536	0.00231076175883882	HAVCR2/PIK3AP1/UNC93B1/RSAD2/IRAK1/RTN4	6
GO:0046851	negative regulation of bone remodeling	6/1068	18/18722	0.000348275834227536	0.00231076175883882	HAMP/P2RX7/CSK/GPR137B/INPP5D/TNFAIP3	6
GO:0071800	podosome assembly	6/1068	18/18722	0.000348275834227536	0.00231076175883882	LCP1/MSN/RHOA/HCK/GSN/DBNL	6
GO:1900225	regulation of NLRP3 inflammasome complex assembly	6/1068	18/18722	0.000348275834227536	0.00231076175883882	TREM2/CD36/TLR4/GBP5/MYD88/EIF2AK2	6
GO:1990840	response to lectin	6/1068	18/18722	0.000348275834227536	0.00231076175883882	TYROBP/CLEC7A/LYN/SYK/PAK2/PAK1	6
GO:1990858	cellular response to lectin	6/1068	18/18722	0.000348275834227536	0.00231076175883882	TYROBP/CLEC7A/LYN/SYK/PAK2/PAK1	6
GO:0002064	epithelial cell development	26/1068	220/18722	0.000348584149683988	0.00231076175883882	VIM/GPX1/CXCR4/MSN/HIF1A/PECAM1/FLNA/RAP1A/SLC4A7/VEGFA/ST14/PRDM1/MYADM/NOTCH2/MYD88/CDKN1A/IL1B/FNDC3A/ARID4A/IQGAP1/TNFRSF1A/ROCK1/RILPL2/PLEC/HSD17B4/RAB13	26
GO:0050435	amyloid-beta metabolic process	12/1068	67/18722	0.000363548762188434	0.00240700505615802	APOE/SORL1/IFNGR1/PRNP/APH1B/ABCG1/RTN4/ROCK1/RTN3/TMED10/ADAM10/PICALM	12
GO:0051494	negative regulation of cytoskeleton organization	21/1068	162/18722	0.000365807930076814	0.00241899459643932	TMSB4X/CAPG/GMFG/TMSB10/TWF2/CIB1/CORO1A/WAS/MYADM/ARHGEF2/ARAP1/CAPZA2/CAPZA1/PAK2/APC/GSN/FLII/TAOK1/PIK3R1/CAPZB/PFN1	21
GO:0031579	membrane raft organization	7/1068	25/18722	0.000373644321986507	0.00246176405548131	PPT1/PTPRC/DOCK2/MYADM/GSN/FLOT1/S100A10	7
GO:0035902	response to immobilization stress	7/1068	25/18722	0.000373644321986507	0.00246176405548131	SOD2/FOS/SLC8A1/HNMT/ACTR2/PTK2B/ERCC1	7
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	7/1068	25/18722	0.000373644321986507	0.00246176405548131	SLC15A3/HSPA1A/TLR4/LACC1/TNFAIP3/NFKBIA/XIAP	7
GO:0043666	regulation of phosphoprotein phosphatase activity	11/1068	58/18722	0.00037928843611701	0.00249590292839925	LGALS3/NCKAP1L/PTPRC/GNAI2/CD300A/JAK2/CD33/CALM3/ROCK1/PPP1R15A/BOD1L1	11
GO:0031345	negative regulation of cell projection organization	23/1068	186/18722	0.000392696436840501	0.00258098656905158	APOE/SPP1/LGALS1/VIM/B2M/CTSZ/YWHAH/FLNA/RHOA/CIB1/PRNP/PMP22/ABI3/LRRK2/ARHGAP4/RAB29/LRP1/RTN4/ARHGAP24/DENND5A/ARF6/UBE3A/CAPZB	23
GO:0007173	epidermal growth factor receptor signaling pathway	16/1068	108/18722	0.000403424509704454	0.00264827086905746	PLAUR/CCDC88A/GRB2/HBEGF/TGFB1/NCF1/RASSF2/RHBDF2/PTK2B/PTPRJ/DUSP3/IQGAP1/ADAM17/SHKBP1/NUP62/RAB7A	16
GO:0030282	bone mineralization	17/1068	119/18722	0.000417205398100309	0.0027354074461109	GPNMB/CCL3/SRGN/ISG15/SNX10/SLC8A1/BMP2K/HIF1A/MEF2C/ALOX5/P2RX7/CCR1/TGFB1/FGR/PTK2B/FBXL15/KLF10	17
GO:0046686	response to cadmium ion	12/1068	68/18722	0.000418895099116311	0.00274315285780536	B2M/SOD2/FOS/HMOX1/CYBB/JUN/PRNP/NCF1/MT1X/ERCC1/SLC30A1/UBE2D3	12
GO:0034110	regulation of homotypic cell-cell adhesion	8/1068	33/18722	0.000421871506195355	0.00274929788336973	LGALS1/CD9/PLAUR/LYN/SYK/JAK1/JAK2/SH2B3	8
GO:0036336	dendritic cell migration	8/1068	33/18722	0.000421871506195355	0.00274929788336973	CXCR4/SPI1/LGALS9/GPR183/ALOX5/CCR1/TRPM2/CDC42	8
GO:0045648	positive regulation of erythrocyte differentiation	8/1068	33/18722	0.000421871506195355	0.00274929788336973	ISG15/STAT1/HIF1A/NCKAP1L/HSPA1A/INPP5D/STAT3/SMAP1	8
GO:1902992	negative regulation of amyloid precursor protein catabolic process	8/1068	33/18722	0.000421871506195355	0.00274929788336973	APOE/SORL1/PRNP/RTN4/ROCK1/RTN3/TMED10/PICALM	8
GO:0043491	protein kinase B signaling	25/1068	211/18722	0.000431963147450974	0.00281166844830574	GPX1/CCL3/MTDH/IL18/ZFP36L1/ARRB2/CIB1/AXL/HBEGF/KLF4/TGFB1/HPSE/ENG/ADAM8/PLK3/SH2B3/RRAS/OSBPL8/PTPRJ/IL1B/SESN3/SETX/TGFBR1/RTN4/HCLS1	25
GO:1901361	organic cyclic compound catabolic process	47/1068	495/18722	0.000433049605881211	0.00281534418474098	APOE/SPP1/VIM/TYMP/RNASET2/YWHAH/SAMHD1/ZFP36L2/DNASE2/ZFP36/HMOX1/SLC11A1/SLCO2B1/ZFP36L1/HNMT/UPP1/RNASE6/YBX1/NUDT3/IL4I1/DPYD/HSPA1A/HSD17B11/OAS2/MGAT1/TNFRSF1B/PABPC1/BLVRB/CYP27A1/KYNU/ENTPD1/APOBEC3C/APOBEC3A/MYD88/BTG2/RNASEH2B/HPRT1/MBD4/ACAT1/FAH/ATM/PABPC4/DDX5/ROCK1/BLVRA/BAX/RNH1	47
GO:0051091	positive regulation of DNA-binding transcription factor activity	29/1068	260/18722	0.000436117428508705	0.00283187682819852	MTDH/PYCARD/CLEC7A/IL18/LGALS9/CD36/TRIM22/TLR2/CIB1/HSPA1A/TLR4/VEGFA/CARD16/IRAK1/BTK/CAMK1D/JAK2/ADAM8/TRIM14/IRAK3/MYD88/ARHGEF2/TRIM38/IL1B/STAT3/EIF2AK2/RGCC/HCLS1/FLOT1	29
GO:0001836	release of cytochrome c from mitochondria	11/1068	59/18722	0.000442528103345285	0.00286660461662804	GPX1/PLAUR/SOD2/PYCARD/JUN/ARRB2/HGF/BID/TNFSF10/BAX/PPIF	11
GO:0048278	vesicle docking	11/1068	59/18722	0.000442528103345285	0.00286660461662804	PLEK/STX10/STX6/RAB8B/STXBP2/STX4/STX12/STX7/RAB10/RAB8A/RAB13	11
GO:0045058	T cell selection	10/1068	50/18722	0.000444760366145759	0.00287761023467928	CD74/PTPRC/CD4/RHOA/SYK/DOCK2/IL6R/SPN/STAT6/STAT3	10
GO:0060996	dendritic spine development	15/1068	99/18722	0.000474174369491471	0.00306424538655805	APOE/MEF2C/ACTR2/DOCK10/ABI3/TANC2/LRRK2/PAK2/CFL1/ADAM10/ARF6/ACSL4/CDC42/UBE3A/DBNL	15
GO:0033344	cholesterol efflux	12/1068	69/18722	0.000481184518189648	0.00309825105487257	APOE/APOC1/NPC2/TREM2/SOAT1/PLTP/NR1H3/ABCG1/LRP1/NFKBIA/ABCA1/STX12	12
GO:0002281	macrophage activation involved in immune response	6/1068	19/18722	0.000484581391749058	0.00309825105487257	TYROBP/TREM2/GRN/HAVCR2/SYK/IFI35	6
GO:0002902	regulation of B cell apoptotic process	6/1068	19/18722	0.000484581391749058	0.00309825105487257	CD74/LYN/BTK/BCL6/FNIP1/BAX	6
GO:0044546	NLRP3 inflammasome complex assembly	6/1068	19/18722	0.000484581391749058	0.00309825105487257	TREM2/CD36/TLR4/GBP5/MYD88/EIF2AK2	6
GO:0140131	positive regulation of lymphocyte chemotaxis	6/1068	19/18722	0.000484581391749058	0.00309825105487257	CCL3/CCL4/PTK2B/ADAM17/ADAM10/WNK1	6
GO:1903978	regulation of microglial cell activation	6/1068	19/18722	0.000484581391749058	0.00309825105487257	TREM2/CCL3/GRN/CTSC/PTPRC/LRRK2	6
GO:0002710	negative regulation of T cell mediated immunity	7/1068	26/18722	0.00048632665742718	0.00309825105487257	LILRB4/HLA-F/NCKAP1L/PTPRC/IL4I1/LILRB1/AHR	7
GO:0034114	regulation of heterotypic cell-cell adhesion	7/1068	26/18722	0.00048632665742718	0.00309825105487257	CD44/MBP/KLF4/MYADM/IL1B/WNK1/FLOT1	7
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	7/1068	26/18722	0.00048632665742718	0.00309825105487257	SLC15A3/HSPA1A/TLR4/LACC1/TNFAIP3/NFKBIA/XIAP	7
GO:0045672	positive regulation of osteoclast differentiation	7/1068	26/18722	0.00048632665742718	0.00309825105487257	TYROBP/TREM2/FOS/CCR1/NOTCH2/ATP6AP1/KLF10	7
GO:0051016	barbed-end actin filament capping	7/1068	26/18722	0.00048632665742718	0.00309825105487257	CAPG/TWF2/CAPZA2/CAPZA1/GSN/FLII/CAPZB	7
GO:1904376	negative regulation of protein localization to cell periphery	7/1068	26/18722	0.00048632665742718	0.00309825105487257	GBP1/RHOQ/TGFB1/ABI3/CSK/NUMB/PICALM	7
GO:0046330	positive regulation of JNK cascade	14/1068	89/18722	0.000491410200381172	0.0031269450958217	PYCARD/GADD45B/SDCBP/TAOK3/TLR4/NCF1/RASSF2/MYD88/PTK2B/IL1B/PJA2/CDC42/TAOK1/LTBR	14
GO:0016601	Rac protein signal transduction	9/1068	42/18722	0.000499850203716486	0.00316943795447022	AIF1/RHOG/GABARAP/CYFIP1/RAC1/ARHGAP24/BRK1/ARF6/DBNL	9
GO:0032689	negative regulation of interferon-gamma production	9/1068	42/18722	0.000499850203716486	0.00316943795447022	HLA-DRB1/LAPTM5/HAVCR2/LGALS9/LILRB4/AXL/LILRB1/TLR4/PRNP	9
GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	9/1068	42/18722	0.000499850203716486	0.00316943795447022	FOS/SPI1/JUN/HIF1A/KLF4/TGFB1/STAT3/NR3C1/EGR1	9
GO:0016050	vesicle organization	32/1068	300/18722	0.000500608909916658	0.00317052309613884	SRGN/SNX10/ZEB2/RAB32/SDCBP/CORO1C/CORO1A/SAMD9/STX10/BLOC1S1/STX6/SCARB2/RAB29/RAB8B/TMEM127/ABCG1/ABCA1/STX4/BLOC1S2/STX12/ARL8B/TMED10/PICALM/STX7/CHMP3/RAB8A/KIF5B/ZFYVE16/RAB7A/CHMP1B/RAB13/S100A10	32
GO:0071560	cellular response to transforming growth factor beta stimulus	28/1068	250/18722	0.000508257492126023	0.00321519041912312	LIMS1/ZEB2/ZFP36L2/FOS/SPI1/SKIL/JUN/MEF2C/ZFP36L1/ARRB2/SDCBP/HSPA1A/ZYX/ZMIZ1/TGFB1/ENG/TGFBR2/LPXN/C20orf27/SPRED1/ADAM9/STAT3/HTRA1/TGFBR1/ADAM17/SKI/NR3C1/APPL1	28
GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	11/1068	60/18722	0.000514361226497432	0.00324999201192054	SLC15A3/HSPA1A/TLR4/IRF7/OAS3/IFIH1/LACC1/TNFAIP3/NFKBIA/RNF135/XIAP	11
GO:0051259	protein complex oligomerization	27/1068	238/18722	0.000519660826606331	0.0032796372168044	HLA-DRB1/CD74/B2M/ISG15/SOD2/SAMHD1/KCTD12/ALOX5AP/PYCARD/RNF213/PRNP/GLS/LRRC8C/GBP5/TRPM2/EHD4/VASP/STK4/MCOLN1/HPRT1/ATL3/NINJ1/RNF135/MAT2A/SHKBP1/OXA1L/MICU1	27
GO:0036005	response to macrophage colony-stimulating factor	5/1068	13/18722	0.000523876498475961	0.00328254707978379	TREM2/CSF1R/TLR2/TLR4/DOK1	5
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	5/1068	13/18722	0.000523876498475961	0.00328254707978379	TREM2/CSF1R/TLR2/TLR4/DOK1	5
GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway	5/1068	13/18722	0.000523876498475961	0.00328254707978379	SLC15A3/HSPA1A/TLR4/TNFAIP3/XIAP	5
GO:0071801	regulation of podosome assembly	5/1068	13/18722	0.000523876498475961	0.00328254707978379	LCP1/MSN/RHOA/HCK/GSN	5
GO:1902947	regulation of tau-protein kinase activity	5/1068	13/18722	0.000523876498475961	0.00328254707978379	SORL1/C5AR1/RB1/HGF/EGR1	5
GO:0010922	positive regulation of phosphatase activity	8/1068	34/18722	0.000524380204368723	0.00328254707978379	PLEK/MEF2C/PTPRC/CD300A/JAK2/CD33/CALM3/PPP1R15A	8
GO:0032743	positive regulation of interleukin-2 production	8/1068	34/18722	0.000524380204368723	0.00328254707978379	CD86/CLEC7A/CD83/PTPRC/CD4/RUNX1/SASH3/IL1B	8
GO:0007519	skeletal muscle tissue development	20/1068	155/18722	0.000530517671473597	0.00331625944898466	GPX1/NUPR1/FOS/MEF2C/RB1/VAMP5/GPCPD1/RHOA/TGFB1/SAP30/FOXN2/BTG2/DDX5/SKI/NR4A1/ATF3/FLOT1/MYL6/EGR1/PLEC	20
GO:0072503	cellular divalent inorganic cation homeostasis	46/1068	486/18722	0.000530994841349656	0.00331625944898466	APOE/CYBA/CCL3/CXCR4/FPR3/GPR65/C5AR1/SLC8A1/SLC11A1/C3AR1/CD36/PTPRC/LYN/RMDN3/LPAR6/CD52/TMBIM6/FPR1/CORO1A/PTGER4/P2RX7/PRNP/CCR1/TCIRG1/PTPN6/CCRL2/JAK2/TRPM2/ATP1B1/GNA15/MT1X/ATP2C1/PTK2B/GNA13/MCOLN1/SLC30A1/GRINA/LRP1/ERO1A/CALM3/TMCO1/GNB1/GSTO1/HERPUD1/BAX/MICU1	46
GO:0106106	cold-induced thermogenesis	19/1068	144/18722	0.000547314820331928	0.00341028957333843	FABP5/CXCR4/IL18/CD36/ALDH1A1/RB1/UCP2/SYK/TLR4/VEGFA/SCD/JAK2/NR1H3/ACSL1/STAT6/CEBPB/ADAM17/TLE3/APC	19
GO:0120161	regulation of cold-induced thermogenesis	19/1068	144/18722	0.000547314820331928	0.00341028957333843	FABP5/CXCR4/IL18/CD36/ALDH1A1/RB1/UCP2/SYK/TLR4/VEGFA/SCD/JAK2/NR1H3/ACSL1/STAT6/CEBPB/ADAM17/TLE3/APC	19
GO:0046328	regulation of JNK cascade	18/1068	133/18722	0.000557734472020148	0.0034712055490435	PYCARD/GADD45B/SDCBP/TAOK3/SIRPA/TLR4/MDFIC/NCF1/RASSF2/MYD88/RAP2A/PTK2B/IL1B/DUSP3/PJA2/CDC42/TAOK1/LTBR	18
GO:0001570	vasculogenesis	13/1068	80/18722	0.000561333553502363	0.00348768770340387	JUNB/ZFP36L1/RAP1A/ZMIZ1/VEGFA/TGFB1/ENG/TGFBR2/RIN2/SPRED1/RRAS/SGPL1/QKI	13
GO:0051056	regulation of small GTPase mediated signal transduction	32/1068	302/18722	0.000561675428883981	0.00348768770340387	APOE/GPR65/FBP1/ARHGDIB/TIMP2/LPAR6/DOCK2/PREX1/ARHGAP30/MYO9B/FGD4/NOTCH2/CYTH1/TAGAP/CYTH4/ABR/BCL6/ARHGAP15/ARHGAP4/ARHGEF2/GABARAP/ARHGAP18/GNA13/ARAP1/RAC1/ABCA1/NUP62/ARHGAP24/ARF6/AKAP13/FLOT1/ARHGDIA	32
GO:0018105	peptidyl-serine phosphorylation	33/1068	315/18722	0.00056754881595012	0.00352010736881247	SGK1/CD44/ARRB2/HGF/SYK/VEGFA/STK38L/TGFB1/DDIT4/TGFBR2/CREBL2/CAMK1D/RASSF2/RPS6KA1/SGK3/LRRK2/MAPKAPK3/STK4/FNIP2/PRKX/ATM/RPS6KA3/TGFBR1/PAK2/CAB39/ROCK1/PAK1/MORC3/HCLS1/UHMK1/FNIP1/BAX/WNK1	33
GO:0030522	intracellular receptor signaling pathway	29/1068	265/18722	0.000595572666162247	0.00368967865282604	FABP5/YWHAH/SLC15A3/RHOA/NR4A2/HSPA1A/AHR/TLR4/ZMIZ1/IRF7/JAK2/NCOR2/KLF2/NR1H3/OAS3/IFIH1/LACC1/PRCP/STAT3/TNFAIP3/NFKBIA/DHRS3/RNF135/DDX5/PAK1/NR4A1/UBE3A/XIAP/NR3C1	29
GO:0031952	regulation of protein autophosphorylation	9/1068	43/18722	0.000600573346578739	0.00370788761800787	GPNMB/RAP2B/PTPRC/VEGFA/ENG/RASSF2/RAP2A/CALM3/IQGAP1	9
GO:0035794	positive regulation of mitochondrial membrane permeability	9/1068	43/18722	0.000600573346578739	0.00370788761800787	CHCHD10/HSPA1A/ACAA2/BID/BNIP3L/SLC35F6/BLOC1S2/BAX/PPIF	9
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	9/1068	43/18722	0.000600573346578739	0.00370788761800787	CD74/NUPR1/CD44/PYCARD/IFI16/DDIT4/CDKN1A/RPS27L/ZNF385A	9
GO:0002526	acute inflammatory response	16/1068	112/18722	0.000609462892782153	0.00375847059366	C3/HAMP/NUPR1/HLA-E/ALOX5AP/SERPINA1/CD163/PLSCR1/TREM1/BTK/ADAM8/IL6R/PRCP/IL1B/STAT3/CEBPB	16
GO:0002377	immunoglobulin production	25/1068	216/18722	0.000612881616915078	0.00377523881834904	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQB1/HLA-DQA1/HLA-DMA/B2M/HLA-DMB/HLA-E/HLA-DQA2/SAMHD1/CD86/GAPT/PTPRC/TMBIM6/HLA-DOA/TGFB1/BTK/HLA-DRB5/SASH3/BCL6/STAT6/ERCC1/STX4	25
GO:0006690	icosanoid metabolic process	17/1068	123/18722	0.000615709730950865	0.00378833490103862	CD74/FABP5/GPX1/ALOX5AP/LTA4H/SYK/TLR2/ALOX5/TBXAS1/PTGS1/DPEP2/LTC4S/GPX4/MGST2/IL1B/ABHD12/TNFRSF1A	17
GO:0031954	positive regulation of protein autophosphorylation	7/1068	27/18722	0.000624500538532502	0.00383804658988768	GPNMB/RAP2B/VEGFA/RASSF2/RAP2A/CALM3/IQGAP1	7
GO:1990845	adaptive thermogenesis	20/1068	157/18722	0.000626218166237469	0.00384422437430874	FABP5/CXCR4/SORL1/IL18/CD36/ALDH1A1/RB1/UCP2/SYK/TLR4/VEGFA/SCD/JAK2/NR1H3/ACSL1/STAT6/CEBPB/ADAM17/TLE3/APC	20
GO:0001960	negative regulation of cytokine-mediated signaling pathway	13/1068	81/18722	0.000634358704096498	0.00388977223557353	TREM2/ISG15/SAMHD1/PTPRC/OAS1/STAT2/CARD16/NR1H3/OAS3/SH2B3/IRAK3/PARP14/ADAR	13
GO:0045444	fat cell differentiation	26/1068	229/18722	0.000645541528264618	0.00395304973015215	GPX1/MAFB/ZFP36L2/ZFP36/ID2/PSMB8/ZFP36L1/LPL/RETN/METRNL/NR4A2/ATF5/ALOX5/KLF4/TGFB1/CREBL2/JDP2/OSBPL8/STK4/CEBPB/ERO1A/CEBPA/ZNF385A/NR4A1/RGS2/PIAS1	26
GO:0006691	leukotriene metabolic process	8/1068	35/18722	0.000646143414009302	0.00395304973015215	ALOX5AP/LTA4H/SYK/TLR2/ALOX5/DPEP2/LTC4S/MGST2	8
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	6/1068	20/18722	0.000659063562159096	0.00402297169842815	ISG15/SAMHD1/OAS1/STAT2/OAS3/ADAR	6
GO:0140632	inflammasome complex assembly	6/1068	20/18722	0.000659063562159096	0.00402297169842815	TREM2/CD36/TLR4/GBP5/MYD88/EIF2AK2	6
GO:0070265	necrotic cell death	11/1068	62/18722	0.000687431623754994	0.00418666031803832	NUPR1/TSPO/ASAH1/TMEM123/CASP1/SLC6A6/ARHGEF2/NINJ1/ALKBH7/BAX/PPIF	11
GO:1903078	positive regulation of protein localization to plasma membrane	11/1068	62/18722	0.000687431623754994	0.00418666031803832	TREM2/LGALS3/CIB1/RHOG/PRNP/ATP2C1/LRP1/STX4/ARF6/KIF5B/PIK3R1	11
GO:0006869	lipid transport	39/1068	398/18722	0.000710826090150853	0.00432425883027509	APOE/APOC1/SPP1/FABP5/MSR1/PSAP/NPC2/TREM2/TSPO/PLIN2/CD36/SLCO2B1/SOAT1/PLSCR1/RETN/SYK/APOL6/PLTP/P2RX7/AQP9/OSBPL1A/ABCC3/NR1H3/APOBR/SCARB2/OSBPL8/ACSL1/IL1B/ABCG1/LRP1/NFKBIA/CPT1A/ABCA1/STX12/ARL8B/TMEM30A/ACSL4/SCP2/GM2A	39
GO:0030032	lamellipodium assembly	12/1068	72/18722	0.000716686099556999	0.00434895291972635	CCDC88A/ACTR2/ACTR3/TWF2/WAS/ABI3/CYFIP1/RAC1/BRK1/CDC42/PIK3R1/CAPZB	12
GO:0043903	regulation of biological process involved in symbiotic interaction	12/1068	72/18722	0.000716686099556999	0.00434895291972635	HLA-DRB1/CD74/LGALS1/IFITM3/LGALS9/CD4/TRIM22/CIITA/TRIM14/TRIM38/GSN/CHMP3	12
GO:0042269	regulation of natural killer cell mediated cytotoxicity	9/1068	44/18722	0.000717303205811054	0.00434895291972635	HLA-A/HLA-B/HLA-E/HAVCR2/LGALS9/HLA-F/ARRB2/LILRB1/LAMP1	9
GO:0034381	plasma lipoprotein particle clearance	10/1068	53/18722	0.000722960776586623	0.00437833484900271	APOE/APOC1/MSR1/TREM2/LIPA/HMOX1/CD36/SOAT1/NCEH1/CSK	10
GO:0051604	protein maturation	31/1068	294/18722	0.000737775322575316	0.00446304444015292	CTSZ/CTSS/SRGN/CTSH/SORL1/LGMN/PYCARD/IFI16/CPM/ATP6AP2/CASP1/PRNP/CARD16/PLAU/RUNX1/ADAM8/APH1B/LRRK2/SPCS3/ERO1A/TSPAN14/PGK1/HM13/PRKACB/ADAM17/GSN/FAM111A/ADAM10/CISD3/XIAP/SEC11A	31
GO:0106027	neuron projection organization	14/1068	93/18722	0.000772914201924527	0.00467037517758651	APOE/TREM2/LGMN/ACTR2/DOCK10/PRNP/ABI3/TANC2/LRRK2/CFL1/ADAM10/CDC42/UBE3A/DBNL	14
GO:0001771	immunological synapse formation	5/1068	14/18722	0.0007767903195877	0.00467286573522322	CD81/LGALS3/HAVCR2/MSN/DOCK2	5
GO:0045579	positive regulation of B cell differentiation	5/1068	14/18722	0.0007767903195877	0.00467286573522322	NCKAP1L/SYK/BTK/INPP5D/PPP2R3C	5
GO:0046348	amino sugar catabolic process	5/1068	14/18722	0.0007767903195877	0.00467286573522322	ALDH1A1/MGAT1/GNPDA1/NPL/NAGK	5
GO:1905049	negative regulation of metallopeptidase activity	5/1068	14/18722	0.0007767903195877	0.00467286573522322	TIMP1/SORL1/TIMP2/LRP1/PICALM	5
GO:0010594	regulation of endothelial cell migration	26/1068	232/18722	0.000784798196988314	0.00470188298483675	APOE/TMSB4X/GRN/GLUL/LGMN/HMOX1/HIF1A/MEF2C/RHOA/CIB1/KLF4/VEGFA/SP100/TGFB1/VASH1/RIN2/STAT5A/SPRED1/RRAS/PTK2B/PRCP/RAC1/RGCC/ADAM17/SVBP/RHOB	26
GO:0010762	regulation of fibroblast migration	8/1068	36/18722	0.000789713816985605	0.00470188298483675	SLC8A1/CORO1C/TGFB1/ARHGAP4/RAC1/PAK1/RCC2/APPL1	8
GO:0042092	type 2 immune response	8/1068	36/18722	0.000789713816985605	0.00470188298483675	CD74/CD81/CD86/IL18/RSAD2/BCL6/DENND1B/STAT6	8
GO:0046466	membrane lipid catabolic process	8/1068	36/18722	0.000789713816985605	0.00470188298483675	ASAH1/PPT1/GALC/MGST2/SGPL1/HEXA/ACER3/GM2A	8
GO:0060338	regulation of type I interferon-mediated signaling pathway	8/1068	36/18722	0.000789713816985605	0.00470188298483675	ISG15/SAMHD1/OAS1/STAT2/IRF7/PTPN6/OAS3/ADAR	8
GO:0046902	regulation of mitochondrial membrane permeability	11/1068	63/18722	0.000790632489545914	0.00470188298483675	CHCHD10/HSPA1A/ACAA2/BID/BNIP3L/SLC35F6/STAT3/BLOC1S2/ALKBH7/BAX/PPIF	11
GO:0010575	positive regulation of vascular endothelial growth factor production	7/1068	28/18722	0.000792070354562011	0.00470188298483675	C3/C5AR1/C3AR1/HIF1A/TGFB1/HPSE/IL1B	7
GO:0010818	T cell chemotaxis	7/1068	28/18722	0.000792070354562011	0.00470188298483675	CCL3/CXCL16/GPR183/ADAM17/ADAM10/WNK1/PLEC	7
GO:0032607	interferon-alpha production	7/1068	28/18722	0.000792070354562011	0.00470188298483675	STAT1/HAVCR2/TLR7/TLR4/IRF7/TLR8/IFIH1	7
GO:0032647	regulation of interferon-alpha production	7/1068	28/18722	0.000792070354562011	0.00470188298483675	STAT1/HAVCR2/TLR7/TLR4/IRF7/TLR8/IFIH1	7
GO:0051894	positive regulation of focal adhesion assembly	7/1068	28/18722	0.000792070354562011	0.00470188298483675	LIMS1/VEGFA/PTPRJ/RAC1/IQGAP1/ROCK1/S100A10	7
GO:1902624	positive regulation of neutrophil migration	7/1068	28/18722	0.000792070354562011	0.00470188298483675	CD74/C5AR1/C3AR1/NCKAP1L/CAMK1D/ADAM8/RAC1	7
GO:0010977	negative regulation of neuron projection development	18/1068	137/18722	0.000796232424580763	0.00472139578355802	APOE/SPP1/LGALS1/VIM/B2M/CTSZ/FLNA/RHOA/CIB1/PMP22/LRRK2/ARHGAP4/RAB29/LRP1/RTN4/DENND5A/ARF6/UBE3A	18
GO:0090316	positive regulation of intracellular protein transport	20/1068	160/18722	0.000797644523166287	0.00472457721954477	CD81/ITGB2/SORL1/FLNA/CIB1/OAZ1/PRNP/TGFB1/ITGAM/JAK2/PLK3/RAB29/IL1B/PAK1/TMEM30A/HCLS1/CDC42/UBE2D3/KIF5B/PIK3R1	20
GO:2001235	positive regulation of apoptotic signaling pathway	17/1068	126/18722	0.000813362647525934	0.00481239566452844	NUPR1/CTSH/PYCARD/CTSC/SKIL/PTPRC/PEA15/TNFSF12/BID/TNFSF10/STK4/MCL1/TGFBR1/PAK2/BAX/LTBR/ATF3	17
GO:0043087	regulation of GTPase activity	35/1068	348/18722	0.000824295178471578	0.00487173798798755	RGS1/CCL3/CCL3L3/GPR65/LIMS1/RGS10/ADAP2/PYCARD/ARRB2/PLXNC1/DOCK10/CCL4/CORO1C/RAP1A/RHOG/PREX1/PLXND1/FGD4/GPR137B/ABR/TBC1D2/BCL6/ARHGAP15/LRRK2/DENND1B/PTK2B/ARAP1/IQGAP1/ARHGAP24/CCPG1/PICALM/TBC1D9B/RCC2/WNK1/S100A10	35
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	10/1068	54/18722	0.000842616335997275	0.0049691341519577	HAVCR2/LILRB4/HLA-F/NCKAP1L/PTPRC/IL4I1/LILRB1/AHR/PTPN6/BCL6	10
GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	10/1068	54/18722	0.000842616335997275	0.0049691341519577	FOS/SPI1/JUN/LILRB4/HIF1A/KLF4/TGFB1/STAT3/NR3C1/EGR1	10
GO:0002920	regulation of humoral immune response	9/1068	45/18722	0.00085188397991223	0.00501830344498515	TREM2/C3/A2M/PTPRC/PTPN6/VSIG4/IL1B/SERPING1/PPP2R3C	9
GO:0019080	viral gene expression	14/1068	94/18722	0.000861451141955226	0.00506360605881307	CCL3/ZFP36/IFITM3/MGAT4A/JUN/USF2/CCL4/MGAT1/PARP9/MDFIC/TRIM14/SPCS3/CANX/PCBP2	14
GO:0032091	negative regulation of protein binding	14/1068	94/18722	0.000861451141955226	0.00506360605881307	B2M/CTSZ/SORL1/ACTB/ARRB2/IFIT2/TMBIM6/IFIT1/CARD16/ITGA4/LRRK2/CDKN1A/ROCK1/BAX	14
GO:0019370	leukotriene biosynthetic process	6/1068	21/18722	0.000878495743104671	0.00513582126738115	ALOX5AP/LTA4H/SYK/ALOX5/LTC4S/MGST2	6
GO:0030449	regulation of complement activation	6/1068	21/18722	0.000878495743104671	0.00513582126738115	TREM2/C3/A2M/VSIG4/IL1B/SERPING1	6
GO:0032516	positive regulation of phosphoprotein phosphatase activity	6/1068	21/18722	0.000878495743104671	0.00513582126738115	PTPRC/CD300A/JAK2/CD33/CALM3/PPP1R15A	6
GO:0051767	nitric-oxide synthase biosynthetic process	6/1068	21/18722	0.000878495743104671	0.00513582126738115	STAT1/TLR2/TLR4/JAK2/NAMPT/LRRK2	6
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	6/1068	21/18722	0.000878495743104671	0.00513582126738115	STAT1/TLR2/TLR4/JAK2/NAMPT/LRRK2	6
GO:0006970	response to osmotic stress	13/1068	84/18722	0.000903175124340621	0.00526868429291026	TSPO/ZFP36L1/HNMT/AQP9/LRRC8C/PLK3/RCSD1/TSC22D3/ARHGEF2/PTK2B/CAB39/BAX/MICU1	13
GO:0010921	regulation of phosphatase activity	13/1068	84/18722	0.000903175124340621	0.00526868429291026	PLEK/LGALS3/MEF2C/NCKAP1L/PTPRC/GNAI2/CD300A/JAK2/CD33/CALM3/ROCK1/PPP1R15A/BOD1L1	13
GO:0030837	negative regulation of actin filament polymerization	11/1068	64/18722	0.000906356019491061	0.00528153032524164	TMSB4X/CAPG/TMSB10/TWF2/MYADM/CAPZA2/CAPZA1/GSN/FLII/CAPZB/PFN1	11
GO:0031647	regulation of protein stability	31/1068	298/18722	0.0009225452045754	0.00537006895780891	TYROBP/CD81/GRN/CTSH/PYCARD/MFSD1/IFI30/LAMP2/FLNA/CTSA/HSPA1A/PRNP/CREBL2/RASSF2/ATP1B1/LRRK2/RNF149/STK4/CRTAP/STX12/RTN4/GSN/USP3/MORC3/GNAQ/LAMP1/FLOT1/CAMLG/ATP1B3/PIK3R1/PFN1	31
GO:0090150	establishment of protein localization to membrane	28/1068	260/18722	0.000941654314392626	0.00547539512980885	ITGB2/VAMP5/SSR3/SDCBP/CIB1/PRNP/GGA2/CSK/ITGAM/NCF1/BID/ATP1B1/ATP2C1/GGA1/RAB8B/SSR1/EMC3/TRAM1/CALM3/RILPL2/PAK1/ATG3/OXA1L/BAX/RAB10/RAB8A/CAMLG/RAB7A	28
GO:0007179	transforming growth factor beta receptor signaling pathway	23/1068	198/18722	0.00094523352564666	0.00549029074745897	ZEB2/FOS/SPI1/SKIL/JUN/ARRB2/SDCBP/HSPA1A/ZYX/ZMIZ1/TGFB1/ENG/TGFBR2/LPXN/C20orf27/SPRED1/ADAM9/STAT3/HTRA1/TGFBR1/ADAM17/SKI/APPL1	23
GO:0006623	protein targeting to vacuole	8/1068	37/18722	0.000957828963532658	0.00555746783572282	LAPTM5/SORL1/LAMP2/M6PR/VPS13C/SCARB2/ZFYVE16/RAB7A	8
GO:1905517	macrophage migration	10/1068	55/18722	0.000978065301149725	0.00566878664339841	TREM2/CD9/CD81/CCL3/C5AR1/LGALS3/CSF1R/C3AR1/CKLF/PTK2B	10
GO:1905477	positive regulation of protein localization to membrane	15/1068	106/18722	0.000984801403644851	0.00570170426402104	TREM2/CD81/ITGB2/LGALS3/CIB1/RHOG/PRNP/ITGAM/ATP2C1/LRP1/STX4/PAK1/ARF6/KIF5B/PIK3R1	15
GO:0001773	myeloid dendritic cell activation	7/1068	29/18722	0.0009932366010226	0.0057443780269217	PYCARD/SPI1/HAVCR2/DOCK2/TGFBR2/NOTCH2/LTBR	7
GO:0061028	establishment of endothelial barrier	9/1068	46/18722	0.00100628255876142	0.00580738041398571	MSN/PECAM1/RAP1A/VEGFA/MYADM/MYD88/IL1B/TNFRSF1A/ROCK1	9
GO:0071827	plasma lipoprotein particle organization	9/1068	46/18722	0.00100628255876142	0.00580738041398571	APOE/APOC1/PLA2G7/SOAT1/LPL/PLTP/ABCG1/ABCA1/PRKACB	9
GO:0071277	cellular response to calcium ion	13/1068	85/18722	0.00101166114955527	0.0058321832938037	LGMN/FOS/ALOX5AP/MEF2A/JUNB/MEF2C/SLC25A24/TRPM2/MCOLN1/FOSB/IQGAP1/WNK1/PPIF	13
GO:0048545	response to steroid hormone	34/1068	339/18722	0.00101899103227294	0.00586817034166999	SPP1/CYBA/AIF1/TXNIP/TSPO/YWHAH/ZFP36L2/FOS/DUSP1/ZFP36/CYBB/ZFP36L1/HNMT/RHOA/TLR2/ZMIZ1/TGFB1/DDIT4/ENG/TGFBR2/PTAFR/JAK2/NCOR2/ABHD2/NR1H3/CDKN1A/ADAM9/FOSB/CALM3/DDX5/PAK1/UBE3A/NR3C1/ATP1A1	34
GO:0050871	positive regulation of B cell activation	19/1068	152/18722	0.00106567684995076	0.00613048217732869	CD74/CD81/TNFSF13B/MEF2C/NCKAP1L/PTPRC/GPR183/SYK/TLR4/TGFB1/BTK/SASH3/BCL6/INPP5D/CDKN1A/STAT6/SH3KBP1/BST1/PPP2R3C	19
GO:0006605	protein targeting	32/1068	314/18722	0.0010856253614438	0.0062385883390317	LAPTM5/TSPO/ITGB2/SORL1/LAMP2/SSR3/M6PR/HOMER3/SDCBP/CIB1/PRNP/VPS13C/ITGAM/NCF1/BID/LRRK2/BNIP3L/SCARB2/GABARAP/RAB8B/SPCS3/SSR1/MAN1A1/NUCB1/TRAM1/PAK1/ATG3/HERPUD1/UBE2D3/ZFYVE16/YWHAG/RAB7A	32
GO:0010876	lipid localization	42/1068	448/18722	0.00109621652149018	0.00629274930846917	APOE/APOC1/SPP1/FABP5/MSR1/PSAP/NPC2/TREM2/C3/TSPO/PLIN2/CD36/SLCO2B1/SOAT1/LPL/PLSCR1/RETN/SYK/APOL6/PLTP/P2RX7/AQP9/OSBPL1A/ABCC3/NR1H3/APOBR/SCARB2/OSBPL8/ACSL1/IL1B/ABCG1/LRP1/NFKBIA/CPT1A/ABCA1/STX12/ARL8B/TMEM30A/ALKBH7/ACSL4/SCP2/GM2A	42
GO:0030852	regulation of granulocyte differentiation	5/1068	15/18722	0.00111075066398172	0.00634916375301413	C1QC/EVI2B/RUNX1/INPP5D/HCLS1	5
GO:0032488	Cdc42 protein signal transduction	5/1068	15/18722	0.00111075066398172	0.00634916375301413	APOE/WAS/SHTN1/ABCA1/CDC42	5
GO:0048569	post-embryonic animal organ development	5/1068	15/18722	0.00111075066398172	0.00634916375301413	KLF4/VEGFA/ERCC1/LDHA/BAX	5
GO:0060099	regulation of phagocytosis, engulfment	5/1068	15/18722	0.00111075066398172	0.00634916375301413	TREM2/C3/CD36/NCKAP1L/CD300A	5
GO:0001503	ossification	39/1068	408/18722	0.00113513689764475	0.00648169174570481	SPP1/GPNMB/CCL3/SRGN/ISG15/SNX10/SLC8A1/BMP2K/JUNB/HIF1A/MEF2C/HGF/RHOA/CLEC5A/PTGER4/ALOX5/P2RX7/CCR1/TGFB1/TCIRG1/PDLIM7/RUNX1/RASSF2/IL6R/MMP2/FGR/PTK2B/ATP6AP1/DHRS3/CEBPB/FBXL15/ADAR/DDX5/CEBPA/SKI/CLIC1/KLF10/BCAP29/HSD17B4	39
GO:0032727	positive regulation of interferon-alpha production	6/1068	22/18722	0.00115014515033449	0.00655351977951946	STAT1/TLR7/TLR4/IRF7/TLR8/IFIH1	6
GO:0032816	positive regulation of natural killer cell activation	6/1068	22/18722	0.00115014515033449	0.00655351977951946	TYROBP/HLA-E/IL18/HLA-F/AXL/LAMP1	6
GO:1901186	positive regulation of ERBB signaling pathway	8/1068	38/18722	0.00115340846570374	0.00655826352048194	PLAUR/CCDC88A/HBEGF/NCF1/RTN4/ADAM17/SHKBP1/NUP62	8
GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	8/1068	38/18722	0.00115340846570374	0.00655826352048194	CHCHD10/HSPA1A/ACAA2/BID/BNIP3L/SLC35F6/BLOC1S2/BAX	8
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	35/1068	355/18722	0.00116994030184223	0.00664526091446388	VIM/ZEB2/SORL1/FOS/SPI1/SKIL/JUN/ARRB2/SDCBP/NCEH1/HSPA1A/ZYX/ZMIZ1/TGFB1/ENG/TGFBR2/JAK2/NOTCH2/LPXN/C20orf27/SPRED1/ADAM9/STAT3/LRP1/FBXL15/HTRA1/DDX5/TGFBR1/ADAM17/UBE2D1/SKI/XIAP/UBE2D3/EGR1/APPL1	35
GO:0070167	regulation of biomineral tissue development	14/1068	97/18722	0.0011799358327525	0.00666796723489955	CCL3/SRGN/ISG15/SLC8A1/BMP2K/HIF1A/MEF2C/ALOX5/P2RX7/CCR1/TGFB1/PTK2B/CEBPB/ROCK1	14
GO:1990868	response to chemokine	14/1068	97/18722	0.0011799358327525	0.00666796723489955	TREM2/CCL3/CCL3L3/CXCR4/DUSP1/HIF1A/CCL4/RHOA/CIB1/CCR1/CCRL2/SH2B3/PTK2B/WNK1	14
GO:1990869	cellular response to chemokine	14/1068	97/18722	0.0011799358327525	0.00666796723489955	TREM2/CCL3/CCL3L3/CXCR4/DUSP1/HIF1A/CCL4/RHOA/CIB1/CCR1/CCRL2/SH2B3/PTK2B/WNK1	14
GO:0010712	regulation of collagen metabolic process	9/1068	47/18722	0.00118258796215694	0.00666796723489955	VIM/CST3/ARRB2/RAP1A/CIITA/TGFB1/ENG/RUNX1/RGCC	9
GO:0046677	response to antibiotic	9/1068	47/18722	0.00118258796215694	0.00666796723489955	MEF2C/ACTR2/JAK1/CIITA/CRIP1/JAK2/CYB5R4/CPT1A/SLC1A3	9
GO:0051489	regulation of filopodium assembly	9/1068	47/18722	0.00118258796215694	0.00666796723489955	RHOQ/TRPM2/ARAP1/RALA/TGFBR1/ARF6/CDC42/PIK3R1/CAPZB	9
GO:1900744	regulation of p38MAPK cascade	9/1068	47/18722	0.00118258796215694	0.00666796723489955	TREM2/DUSP1/SPI1/GADD45B/HGF/VEGFA/NCF1/IL1B/PJA2	9
GO:2000045	regulation of G1/S transition of mitotic cell cycle	18/1068	142/18722	0.00121280724315338	0.00683121908565307	GPNMB/AIF1/ID2/RB1/KLF4/BID/PTPN6/PLK3/SLFN11/CDKN1A/KMT2E/RPS27L/RGCC/ATM/ADAM17/APC/PSME2/APPL1	18
GO:0048147	negative regulation of fibroblast proliferation	7/1068	30/18722	0.00123248434191189	0.00692038034230653	FTH1/NUPR1/IFI30/CD300A/SKI/MORC3/BAX	7
GO:0070168	negative regulation of biomineral tissue development	7/1068	30/18722	0.00123248434191189	0.00692038034230653	CCL3/SRGN/HIF1A/CCR1/TGFB1/PTK2B/ROCK1	7
GO:1903579	negative regulation of ATP metabolic process	7/1068	30/18722	0.00123248434191189	0.00692038034230653	NUPR1/TSPO/FBP1/RHOA/DDIT4/STAT3/PPIF	7
GO:0048041	focal adhesion assembly	13/1068	87/18722	0.00126148293647185	0.00707584399709156	LIMS1/RHOA/CORO1C/VEGFA/PTK2B/PTPRJ/RAC1/LRP1/DUSP3/IQGAP1/ROCK1/RCC2/S100A10	13
GO:0060538	skeletal muscle organ development	20/1068	166/18722	0.00126432113780391	0.00708439964651078	GPX1/NUPR1/FOS/MEF2C/RB1/VAMP5/GPCPD1/RHOA/TGFB1/SAP30/FOXN2/BTG2/DDX5/SKI/NR4A1/ATF3/FLOT1/MYL6/EGR1/PLEC	20
GO:0006959	humoral immune response	32/1068	317/18722	0.00126968639362636	0.00710708275934421	HLA-DRB1/HLA-DQB1/HLA-A/C1QB/TREM2/C3/C1QA/CD81/LYZ/C1QC/CFD/HLA-E/CD83/A2M/SLC11A1/MEF2C/PTPRC/GPR183/RNASE6/ALOX5/POU2F2/C2/TREM1/PTPN6/NOTCH2/VSIG4/IL1B/PSMB10/SERPING1/RGCC/BST1/PPP2R3C	32
GO:1904062	regulation of cation transmembrane transport	35/1068	357/18722	0.00128950763403077	0.00721055253184462	TMSB4X/CYBA/TREM2/CTSS/HAMP/FXYD5/YWHAH/CD63/SLC8A1/IFNGR2/MEF2C/LYN/VMP1/FLNA/CORO1A/PRNP/TCIRG1/KCNAB2/KCNE3/PTPN6/ATP1B1/GLRX/PTK2B/SLC30A1/DAPK1/CALM3/CAB39/GSTO1/KLHL24/RGS2/BAX/WNK1/KIF5B/ATP1B3/PPIF	35
GO:0032411	positive regulation of transporter activity	16/1068	120/18722	0.00129917993421576	0.00724961212515849	TMSB4X/TREM2/CTSS/SGK1/IFNGR2/VMP1/PTAFR/KCNE3/NR1H3/ATP1B1/GLRX/CALM3/GSTO1/WNK1/KIF5B/ATP1B3	16
GO:0051897	positive regulation of protein kinase B signaling	16/1068	120/18722	0.00129917993421576	0.00724961212515849	GPX1/CCL3/MTDH/IL18/ARRB2/AXL/HBEGF/TGFB1/HPSE/ENG/ADAM8/OSBPL8/PTPRJ/TGFBR1/RTN4/HCLS1	16
GO:0061756	leukocyte adhesion to vascular endothelial cell	10/1068	57/18722	0.00130254388164091	0.00726087477823794	ITGB2/RHOA/ALOX5/KLF4/PTAFR/IRAK1/SELPLG/ITGA4/SPN/ROCK1	10
GO:0070555	response to interleukin-1	18/1068	143/18722	0.00131526224069037	0.00732241999532078	CYBA/CCL3/CCL3L3/PYCARD/LGALS9/HIF1A/GBP1/HNMT/CCL4/SIRPA/GBP2/IRAK1/KLF2/IRAK3/MYD88/IL1B/CEBPB/EGR1	18
GO:0009743	response to carbohydrate	27/1068	253/18722	0.00131629862777264	0.00732241999532078	HLA-DRB1/LGALS1/CYBA/TREM2/TXNIP/GLUL/SOD2/SLC8A1/CLEC7A/HIF1A/ZFP36L1/LYN/UCP2/LPL/RHOA/RAP1A/TGFBR2/NAMPT/PTK2B/ERCC1/RAC1/ABCG1/LRP1/LDHA/STX4/EGR1/KIF5B	27
GO:0010827	regulation of glucose transmembrane transport	12/1068	77/18722	0.00132000703118064	0.00732794026774765	FABP5/C3/MEF2A/PEA15/RHOQ/RAP1A/CREBL2/PRKAG2/OSBPL8/IL1B/APPL1/PIK3R1	12
GO:0140056	organelle localization by membrane tethering	12/1068	77/18722	0.00132000703118064	0.00732794026774765	PLEK/VMP1/STX10/STX6/RAB8B/STXBP2/STX4/STX12/STX7/RAB10/RAB8A/RAB13	12
GO:0035914	skeletal muscle cell differentiation	11/1068	67/18722	0.00134035662916056	0.00743326245729742	NUPR1/FOS/MEF2C/RB1/SAP30/FOXN2/BTG2/DDX5/NR4A1/ATF3/EGR1	11
GO:0006606	protein import into nucleus	19/1068	155/18722	0.00134707324845922	0.00744353150910124	TXNIP/CD36/FLNA/NUP214/SYK/TGFB1/MDFIC/JAK2/LRRK2/CDKN1A/STAT3/KPNA3/NFKBIA/NUP62/HCLS1/RANBP2/APPL1/PIK3R1/KPNB1	19
GO:0034614	cellular response to reactive oxygen species	19/1068	155/18722	0.00134707324845922	0.00744353150910124	SOD2/FOS/JUN/CD36/HGF/AXL/SIRPA/KLF4/NCF1/BTK/KLF2/TRPM2/MMP2/LRRK2/STAT6/TNFAIP3/SETX/RHOB/PPIF	19
GO:1903364	positive regulation of cellular protein catabolic process	19/1068	155/18722	0.00134707324845922	0.00744353150910124	APOE/LAPTM5/TREM2/CD81/HAMP/NUPR1/CTSC/MSN/HSPA1A/PLK3/LRRK2/PTK2B/GABARAP/TNFAIP3/LRP1/CEBPA/HERPUD1/PIAS1/SUMO2	19
GO:0050821	protein stabilization	22/1068	191/18722	0.00134772614610673	0.00744353150910124	TYROBP/GRN/MFSD1/IFI30/LAMP2/FLNA/HSPA1A/CREBL2/RASSF2/ATP1B1/STK4/CRTAP/STX12/RTN4/MORC3/GNAQ/LAMP1/FLOT1/CAMLG/ATP1B3/PIK3R1/PFN1	22
GO:0002715	regulation of natural killer cell mediated immunity	9/1068	48/18722	0.00138301004206926	0.00761502263980175	HLA-A/HLA-B/HLA-E/HAVCR2/LGALS9/HLA-F/ARRB2/LILRB1/LAMP1	9
GO:0090199	regulation of release of cytochrome c from mitochondria	9/1068	48/18722	0.00138301004206926	0.00761502263980175	GPX1/PLAUR/PYCARD/ARRB2/HGF/BID/TNFSF10/BAX/PPIF	9
GO:1903053	regulation of extracellular matrix organization	9/1068	48/18722	0.00138301004206926	0.00761502263980175	CST3/RB1/TNFRSF1B/TGFB1/COLGALT1/RUNX1/RGCC/LRP1/TNFRSF1A	9
GO:0010324	membrane invagination	18/1068	144/18722	0.0014249690150273	0.00783805586655177	MSR1/TREM2/C3/AIF1/ITGB2/FCGR1A/CD36/NCKAP1L/RHOA/MARCO/CD300A/RHOG/ITGAM/RAC1/ABCA1/GSN/FCHO2/CDC42	18
GO:0110149	regulation of biomineralization	14/1068	99/18722	0.00144286471763065	0.00792840938526982	CCL3/SRGN/ISG15/SLC8A1/BMP2K/HIF1A/MEF2C/ALOX5/P2RX7/CCR1/TGFB1/PTK2B/CEBPB/ROCK1	14
GO:0014812	muscle cell migration	15/1068	110/18722	0.00144500754160826	0.00793210650510495	AIF1/SORL1/PLEKHO1/DOCK4/MEF2C/RHOA/TLR4/PLAU/GNA13/LRP1/IQGAP1/ROCK1/PAK1/ARPC5/S100A11	15
GO:0030500	regulation of bone mineralization	12/1068	78/18722	0.00148066452965702	0.00808432441307102	CCL3/SRGN/ISG15/SLC8A1/BMP2K/HIF1A/MEF2C/ALOX5/P2RX7/CCR1/TGFB1/PTK2B	12
GO:0032024	positive regulation of insulin secretion	12/1068	78/18722	0.00148066452965702	0.00808432441307102	HLA-DRB1/GLUL/HIF1A/JAK2/TRPM2/SERP1/RAC1/ABCG1/LRP1/STX4/ACSL4/KIF5B	12
GO:0090559	regulation of membrane permeability	12/1068	78/18722	0.00148066452965702	0.00808432441307102	LAPTM5/CHCHD10/HSPA1A/ACAA2/BID/BNIP3L/SLC35F6/STAT3/BLOC1S2/ALKBH7/BAX/PPIF	12
GO:0010888	negative regulation of lipid storage	6/1068	23/18722	0.00148172662055731	0.00808432441307102	TREM2/NR1H3/OSBPL8/ABCG1/NFKBIA/ABCA1	6
GO:0060396	growth hormone receptor signaling pathway	6/1068	23/18722	0.00148172662055731	0.00808432441307102	LYN/JAK2/STAT5A/STAT6/STAT3/PIK3R1	6
GO:0072677	eosinophil migration	6/1068	23/18722	0.00148172662055731	0.00808432441307102	CCL3/LGALS3/CCL4/CD300A/PTGER4/ADAM8	6
GO:0030149	sphingolipid catabolic process	7/1068	31/18722	0.00151456871755514	0.00823022437052121	ASAH1/PPT1/GALC/SGPL1/HEXA/ACER3/GM2A	7
GO:0060055	angiogenesis involved in wound healing	7/1068	31/18722	0.00151456871755514	0.00823022437052121	GPX1/CXCR4/ALOX5/VEGFA/HPSE/PRCP/TNFAIP3	7
GO:0110150	negative regulation of biomineralization	7/1068	31/18722	0.00151456871755514	0.00823022437052121	CCL3/SRGN/HIF1A/CCR1/TGFB1/PTK2B/ROCK1	7
GO:1900027	regulation of ruffle assembly	7/1068	31/18722	0.00151456871755514	0.00823022437052121	CORO1C/RHOG/ABI3/CYFIP1/ARHGAP24/RCC2/PFN1	7
GO:0045342	MHC class II biosynthetic process	5/1068	16/18722	0.0015402736172142	0.00831963607456239	SPI1/SLC11A1/TLR4/CIITA/JAK2	5
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	5/1068	16/18722	0.0015402736172142	0.00831963607456239	APOE/TNFRSF1B/ADAM8/ADAM9/IL1B	5
GO:0097284	hepatocyte apoptotic process	5/1068	16/18722	0.0015402736172142	0.00831963607456239	RB1/BID/STK4/GSN/ARF6	5
GO:1905153	regulation of membrane invagination	5/1068	16/18722	0.0015402736172142	0.00831963607456239	TREM2/C3/CD36/NCKAP1L/CD300A	5
GO:2001044	regulation of integrin-mediated signaling pathway	5/1068	16/18722	0.0015402736172142	0.00831963607456239	TIMP1/LIMS1/CD63/FLNA/BST1	5
GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	5/1068	16/18722	0.0015402736172142	0.00831963607456239	PLAUR/LGALS9/JAK2/GSN/BAX	5
GO:0010823	negative regulation of mitochondrion organization	9/1068	49/18722	0.00160987744729504	0.00867822048511893	GPX1/TSPO/ARRB2/HGF/HSPA1A/VAT1/ACAA2/SLC35F6/PPIF	9
GO:0072666	establishment of protein localization to vacuole	9/1068	49/18722	0.00160987744729504	0.00867822048511893	LAPTM5/SORL1/LAMP2/M6PR/VPS13C/SCARB2/TNFAIP3/ZFYVE16/RAB7A	9
GO:0034122	negative regulation of toll-like receptor signaling pathway	8/1068	40/18722	0.00163952244110704	0.00882920468284787	TREM2/ARRB2/LYN/CD300A/CD300LF/LILRA2/IRAK3/TNFAIP3	8
GO:0048813	dendrite morphogenesis	18/1068	146/18722	0.00166776461975119	0.00895111932616005	YWHAH/MEF2A/PHACTR1/ACTR2/DOCK10/SDC2/ABI3/TANC2/LRRK2/RAP2A/ABI1/HPRT1/CFL1/ADAM10/PICALM/CDC42/UBE3A/DBNL	18
GO:0042989	sequestering of actin monomers	4/1068	10/18722	0.00167543189759482	0.00895111932616005	TMSB4X/TMSB10/TWF2/GSN	4
GO:0044351	macropinocytosis	4/1068	10/18722	0.00167543189759482	0.00895111932616005	PYCARD/DOCK2/MAPKAPK3/APPL1	4
GO:0090647	modulation of age-related behavioral decline	4/1068	10/18722	0.00167543189759482	0.00895111932616005	B2M/PRNP/BAZ2B/PICALM	4
GO:1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	4/1068	10/18722	0.00167543189759482	0.00895111932616005	SORL1/LYN/TMED10/PICALM	4
GO:1903980	positive regulation of microglial cell activation	4/1068	10/18722	0.00167543189759482	0.00895111932616005	TREM2/CCL3/CTSC/LRRK2	4
GO:2000425	regulation of apoptotic cell clearance	4/1068	10/18722	0.00167543189759482	0.00895111932616005	TREM2/C3/C2/CD300LF	4
GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	4/1068	10/18722	0.00167543189759482	0.00895111932616005	LGALS9/JAK2/GSN/BAX	4
GO:0035306	positive regulation of dephosphorylation	10/1068	59/18722	0.001709656248325	0.00912493087632218	PLEK/MEF2C/PTPRC/CD300A/TGFB1/LILRB2/JAK2/CD33/CALM3/PPP1R15A	10
GO:1904377	positive regulation of protein localization to cell periphery	11/1068	69/18722	0.00171485457679587	0.00914363171580092	TREM2/LGALS3/CIB1/RHOG/PRNP/ATP2C1/LRP1/STX4/ARF6/KIF5B/PIK3R1	11
GO:0046700	heterocycle catabolic process	41/1068	445/18722	0.00173067427573873	0.00921118586989952	VIM/TYMP/RNASET2/SAMHD1/ZFP36L2/DNASE2/ZFP36/HMOX1/SLC11A1/SLCO2B1/ZFP36L1/HNMT/UPP1/RNASE6/YBX1/NUDT3/IL4I1/DPYD/HSPA1A/OAS2/MGAT1/TNFRSF1B/PABPC1/BLVRB/KYNU/ENTPD1/APOBEC3C/APOBEC3A/MYD88/BTG2/RNASEH2B/HPRT1/MBD4/ACAT1/ATM/PABPC4/DDX5/ROCK1/BLVRA/BAX/RNH1	41
GO:0035304	regulation of protein dephosphorylation	13/1068	90/18722	0.00173093818978468	0.00921118586989952	LGALS3/NCKAP1L/PTPRC/GNAI2/CD300A/TGFB1/LILRB2/JAK2/CD33/CALM3/ROCK1/PPP1R15A/BOD1L1	13
GO:0043406	positive regulation of MAP kinase activity	15/1068	112/18722	0.00173550994945882	0.00922641545544809	TAOK3/SYK/TLR4/VEGFA/TGFB1/CSK/IRAK1/ADAM8/LRRK2/PTK2B/ADAM9/IL1B/IQGAP1/PAK1/AKAP13	15
GO:0051170	import into nucleus	19/1068	159/18722	0.00181863486981323	0.00965881275345687	TXNIP/CD36/FLNA/NUP214/SYK/TGFB1/MDFIC/JAK2/LRRK2/CDKN1A/STAT3/KPNA3/NFKBIA/NUP62/HCLS1/RANBP2/APPL1/PIK3R1/KPNB1	19
GO:0050850	positive regulation of calcium-mediated signaling	7/1068	32/18722	0.00184449771829413	0.00976733041012282	TREM2/CCL3/CLEC7A/CD4/CCL4/SYK/CIB1	7
GO:0090022	regulation of neutrophil chemotaxis	7/1068	32/18722	0.00184449771829413	0.00976733041012282	CD74/C5AR1/C3AR1/NCKAP1L/CAMK1D/RAC1/BST1	7
GO:1905476	negative regulation of protein localization to membrane	7/1068	32/18722	0.00184449771829413	0.00976733041012282	GBP1/RHOQ/TGFB1/ABI3/CSK/NUMB/PICALM	7
GO:0009791	post-embryonic development	12/1068	80/18722	0.00185047641086589	0.00977979501766147	NR4A2/ATF5/KLF4/VEGFA/PRDM1/ERCC1/SGPL1/SERP1/IGF2R/TGFBR1/MORC3/BAX	12
GO:0048145	regulation of fibroblast proliferation	12/1068	80/18722	0.00185047641086589	0.00977979501766147	CD74/FTH1/NUPR1/IFI30/CD300A/ZMIZ1/S100A6/CDKN1A/RNASEH2B/SKI/MORC3/BAX	12
GO:0045927	positive regulation of growth	27/1068	259/18722	0.0018527936830631	0.0097824605810259	CYBA/HAMP/CXCR4/CXCL16/MEF2C/SDCBP/RHOA/TWF2/CIB1/HBEGF/VEGFA/TGFBR2/RPS6KA1/SASH3/ITSN2/PTK2B/CYFIP1/SERP1/SHTN1/LRP1/RPS6KA3/TGFBR1/ADAM17/PAK1/ADAM10/CDC42/DBNL	27
GO:0071825	protein-lipid complex subunit organization	9/1068	50/18722	0.0018656348553522	0.00984063116273752	APOE/APOC1/PLA2G7/SOAT1/LPL/PLTP/ABCG1/ABCA1/PRKACB	9
GO:0018209	peptidyl-serine modification	33/1068	338/18722	0.00186858795535338	0.00984658262410825	SGK1/CD44/ARRB2/HGF/SYK/VEGFA/STK38L/TGFB1/DDIT4/TGFBR2/CREBL2/CAMK1D/RASSF2/RPS6KA1/SGK3/LRRK2/MAPKAPK3/STK4/FNIP2/PRKX/ATM/RPS6KA3/TGFBR1/PAK2/CAB39/ROCK1/PAK1/MORC3/HCLS1/UHMK1/FNIP1/BAX/WNK1	33
GO:0043393	regulation of protein binding	22/1068	196/18722	0.00187950235127238	0.0098656654120154	APOE/B2M/CTSZ/SORL1/ACTB/ARRB2/IFIT2/TMBIM6/IFIT1/CARD16/PLXND1/DTX3L/ITGA4/LRRK2/STK4/CDKN1A/LRP1/TGFBR1/ROCK1/CDC42/BAX/FLOT1	22
GO:0001783	B cell apoptotic process	6/1068	24/18722	0.00188135094680575	0.0098656654120154	CD74/LYN/BTK/BCL6/FNIP1/BAX	6
GO:0006213	pyrimidine nucleoside metabolic process	6/1068	24/18722	0.00188135094680575	0.0098656654120154	TYMP/UPP1/DPYD/APOBEC3C/APOBEC3A/TK2	6
GO:0071378	cellular response to growth hormone stimulus	6/1068	24/18722	0.00188135094680575	0.0098656654120154	LYN/JAK2/STAT5A/STAT6/STAT3/PIK3R1	6
GO:0090023	positive regulation of neutrophil chemotaxis	6/1068	24/18722	0.00188135094680575	0.0098656654120154	CD74/C5AR1/C3AR1/NCKAP1L/CAMK1D/RAC1	6
GO:0071347	cellular response to interleukin-1	15/1068	113/18722	0.00189811186559513	0.0099438947832537	CCL3/CCL3L3/PYCARD/HIF1A/GBP1/CCL4/SIRPA/GBP2/IRAK1/KLF2/IRAK3/MYD88/IL1B/CEBPB/EGR1	15
GO:0099024	plasma membrane invagination	17/1068	136/18722	0.00190722530614876	0.00998194738310254	MSR1/TREM2/C3/AIF1/ITGB2/FCGR1A/CD36/NCKAP1L/RHOA/MARCO/CD300A/RHOG/ITGAM/RAC1/ABCA1/GSN/CDC42	17
GO:0002548	monocyte chemotaxis	11/1068	70/18722	0.00193182721069181	0.0100911322641752	AIF1/CCL3/CCL3L3/LGMN/DUSP1/LGALS3/PLA2G7/LYN/CCL4/CCR1/IL6R	11
GO:0045123	cellular extravasation	11/1068	70/18722	0.00193182721069181	0.0100911322641752	PECAM1/SIRPA/PTGER4/PTAFR/ADAM8/SELPLG/ITGA4/SPN/ITGAL/BST1/ROCK1	11
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	8/1068	41/18722	0.00193676131096434	0.0100973565545542	LIMS1/FLNA/CIB1/PREX1/MYADM/RAC1/CDC42/S100A10	8
GO:1905521	regulation of macrophage migration	8/1068	41/18722	0.00193676131096434	0.0100973565545542	TREM2/CD9/CD81/CCL3/C5AR1/CSF1R/C3AR1/PTK2B	8
GO:2001056	positive regulation of cysteine-type endopeptidase activity	18/1068	148/18722	0.00194459788835808	0.0101284268393631	CTSD/LAPTM5/CTSH/LGMN/PYCARD/IFI16/CLEC7A/LGALS9/RHOA/SYK/CASP1/BID/JAK2/TNFSF10/RPS27L/DAPK1/GSN/BAX	18
GO:0042594	response to starvation	22/1068	197/18722	0.00200492551135628	0.0104325728633351	GLUL/HAMP/IFI16/ZFP36/JUN/UPP1/LAMP2/UCP2/PDK4/EIF4EBP1/RRAGD/LRRK2/PRKAG2/GABARAP/CDKN1A/ACAT1/EIF2AK2/SESN3/MAX/KLF10/FNIP1/ATF3	22
GO:0051480	regulation of cytosolic calcium ion concentration	34/1068	353/18722	0.0020141253837076	0.0104703473704106	CYBA/CCL3/CXCR4/FPR3/GPR65/C5AR1/SLC8A1/C3AR1/CD36/PTPRC/LYN/LPAR6/CD52/TMBIM6/FPR1/CORO1A/PTGER4/P2RX7/PRNP/CCR1/PTPN6/CCRL2/JAK2/TRPM2/GNA15/PTK2B/GNA13/MCOLN1/LRP1/ERO1A/CALM3/GNB1/GSTO1/BAX	34
GO:0051896	regulation of protein kinase B signaling	21/1068	185/18722	0.00205244756148859	0.0106592945541795	GPX1/CCL3/MTDH/IL18/ARRB2/CIB1/AXL/HBEGF/KLF4/TGFB1/HPSE/ENG/ADAM8/SH2B3/RRAS/OSBPL8/PTPRJ/SESN3/TGFBR1/RTN4/HCLS1	21
GO:0048144	fibroblast proliferation	12/1068	81/18722	0.00206197514247795	0.0106984787200106	CD74/FTH1/NUPR1/IFI30/CD300A/ZMIZ1/S100A6/CDKN1A/RNASEH2B/SKI/MORC3/BAX	12
GO:0032604	granulocyte macrophage colony-stimulating factor production	5/1068	17/18722	0.00208042639984229	0.0107425654100947	CD84/IL18/SYK/LILRA2/IL1B	5
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	5/1068	17/18722	0.00208042639984229	0.0107425654100947	CD84/IL18/SYK/LILRA2/IL1B	5
GO:0035855	megakaryocyte development	5/1068	17/18722	0.00208042639984229	0.0107425654100947	PTPN6/SH2B3/FLI1/ABI1/ZNF385A	5
GO:0055119	relaxation of cardiac muscle	5/1068	17/18722	0.00208042639984229	0.0107425654100947	SLC8A1/ATP1B1/GSN/RGS2/ATP1A1	5
GO:0060263	regulation of respiratory burst	5/1068	17/18722	0.00208042639984229	0.0107425654100947	GRN/CLEC7A/NCF1/CAMK1D/RAC1	5
GO:0051592	response to calcium ion	18/1068	149/18722	0.00209690873116777	0.0108173226705366	TXNIP/LGMN/FOS/ALOX5AP/DUSP1/MEF2A/JUNB/MEF2C/SLC25A24/TRPM2/PTK2B/MCOLN1/ADAM9/FOSB/CALM3/IQGAP1/WNK1/PPIF	18
GO:0043550	regulation of lipid kinase activity	11/1068	71/18722	0.00217061692451867	0.0111868662127056	CD81/LYN/RB1/KLF4/TGFB1/FGR/PTK2B/SOCS3/CDC42/PIK3R1/SOCS6	11
GO:0009636	response to toxic substance	27/1068	262/18722	0.00218508946323331	0.0112507087248158	APOE/GPX1/CCL3/NUPR1/SOD2/FOS/ALOX5AP/CD36/ALDH1A1/LYN/CCL4/TLR2/MGST1/AHR/MBP/PTGS1/MT1X/GLRX/LTC4S/RDH11/GPX4/CDKN1A/MGST2/SLC30A1/AKR1A1/GSTO1/BAX	27
GO:0050673	epithelial cell proliferation	40/1068	437/18722	0.00220200951200095	0.0113270193772708	APOE/B2M/GPX1/CYBA/GRN/GLUL/NUPR1/C5AR1/STAT1/ZFP36/HMOX1/ID2/HIF1A/MEF2C/ZFP36L1/RB1/HGF/ALOX5/VEGFA/TNFSF12/TGFB1/VASH1/NOTCH2/RPS6KA1/STAT5A/ITGA4/STAT6/PRKX/STAT3/TNFAIP3/RGCC/CEBPB/VEGFB/HTRA1/TGFBR1/RTN4/ADAM17/NR4A1/CDC42/BAX	40
GO:0044270	cellular nitrogen compound catabolic process	41/1068	451/18722	0.00221393106443243	0.0113671106031749	VIM/TYMP/RNASET2/SAMHD1/ZFP36L2/DNASE2/ZFP36/HMOX1/SLC11A1/SLCO2B1/ZFP36L1/HNMT/UPP1/RNASE6/YBX1/NUDT3/IL4I1/DPYD/HSPA1A/OAS2/MGAT1/TNFRSF1B/PABPC1/BLVRB/KYNU/ENTPD1/APOBEC3C/APOBEC3A/MYD88/BTG2/RNASEH2B/HPRT1/MBD4/ACAT1/ATM/PABPC4/DDX5/ROCK1/BLVRA/BAX/RNH1	41
GO:0060997	dendritic spine morphogenesis	10/1068	61/18722	0.00221401653890601	0.0113671106031749	ACTR2/DOCK10/ABI3/TANC2/LRRK2/CFL1/ADAM10/CDC42/UBE3A/DBNL	10
GO:0001975	response to amphetamine	7/1068	33/18722	0.00222751246770534	0.011425529729789	RGS10/NR4A2/HPRT1/CALM3/NR4A1/RGS2/RANBP2	7
GO:0055076	transition metal ion homeostasis	17/1068	138/18722	0.00223274107583044	0.0114414727874464	FTL/B2M/FTH1/HAMP/HMOX1/SLC11A1/HIF1A/ATP6V0D1/PRNP/ATP6V1A/MT1X/SLC31A1/SCO2/SLC30A1/ATP6AP1/PICALM/XIAP	17
GO:0032965	regulation of collagen biosynthetic process	8/1068	42/18722	0.00227485804208148	0.011646237186975	VIM/ARRB2/RAP1A/CIITA/TGFB1/ENG/RUNX1/RGCC	8
GO:0043242	negative regulation of protein-containing complex disassembly	12/1068	82/18722	0.00229284536006842	0.0117271976899803	CAPG/TWF2/CIB1/IRAK3/ARHGEF2/CAPZA2/CAPZA1/APC/GSN/FLII/TAOK1/CAPZB	12
GO:0032963	collagen metabolic process	14/1068	104/18722	0.00232037635775279	0.0118567716159413	VIM/CTSB/CTSS/CST3/HIF1A/ARRB2/RAP1A/CIITA/TGFB1/ENG/RUNX1/PEPD/MMP2/RGCC	14
GO:0051591	response to cAMP	13/1068	93/18722	0.00233628354394533	0.0119267606462905	FOS/DUSP1/STAT1/SLC8A1/JUN/ZFP36L1/AHR/RAP1A/AQP9/PTAFR/PTK2B/LDHA/FOSB	13
GO:0042832	defense response to protozoan	6/1068	25/18722	0.00235746882832761	0.011968312550788	CLEC7A/SLC11A1/GBP4/IRF8/GBP2/MYD88	6
GO:0048143	astrocyte activation	6/1068	25/18722	0.00235746882832761	0.011968312550788	TREM2/C1QA/GRN/C5AR1/IFNGR1/LRP1	6
GO:0090382	phagosome maturation	6/1068	25/18722	0.00235746882832761	0.011968312550788	RAB32/CORO1A/TCIRG1/MCOLN1/ARL8B/RAB7A	6
GO:1901623	regulation of lymphocyte chemotaxis	6/1068	25/18722	0.00235746882832761	0.011968312550788	CCL3/CCL4/PTK2B/ADAM17/ADAM10/WNK1	6
GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	6/1068	25/18722	0.00235746882832761	0.011968312550788	ITGB2/RHOA/ALOX5/PTAFR/IRAK1/ITGA4	6
GO:0006911	phagocytosis, engulfment	16/1068	127/18722	0.0023577309565396	0.011968312550788	MSR1/TREM2/C3/AIF1/ITGB2/FCGR1A/CD36/NCKAP1L/MARCO/CD300A/RHOG/ITGAM/RAC1/ABCA1/GSN/CDC42	16
GO:0014706	striated muscle tissue development	36/1068	384/18722	0.00239820662568417	0.012162333601684	GPX1/HAMP/NUPR1/FOS/MEF2A/SLC8A1/ID2/MEF2C/ARRB2/RB1/VAMP5/GPCPD1/RHOA/VEGFA/TGFB1/ENG/TGFBR2/RUNX1/NOTCH2/SAP30/FOXN2/BTG2/PRKAR1A/DDX5/TGFBR1/PAK1/SKI/NR4A1/AKAP13/CDC42/RGS2/ATF3/FLOT1/MYL6/EGR1/PLEC	36
GO:0019439	aromatic compound catabolic process	42/1068	467/18722	0.00240388036537101	0.0121782963890087	VIM/TYMP/RNASET2/SAMHD1/ZFP36L2/DNASE2/ZFP36/HMOX1/SLC11A1/SLCO2B1/ZFP36L1/HNMT/UPP1/RNASE6/YBX1/NUDT3/IL4I1/DPYD/HSPA1A/OAS2/MGAT1/TNFRSF1B/PABPC1/BLVRB/KYNU/ENTPD1/APOBEC3C/APOBEC3A/MYD88/BTG2/RNASEH2B/HPRT1/MBD4/ACAT1/FAH/ATM/PABPC4/DDX5/ROCK1/BLVRA/BAX/RNH1	42
GO:0034504	protein localization to nucleus	29/1068	290/18722	0.00240586804126821	0.0121782963890087	TXNIP/GLUL/CHCHD10/LILRB4/CD36/FLNA/NUP214/SYK/GBP2/PARP9/SP100/TGFB1/MDFIC/DTX3L/JAK2/LRRK2/OSBPL8/CDKN1A/STAT3/KPNA3/NFKBIA/SUMO3/NUP62/MORC3/HCLS1/RANBP2/APPL1/PIK3R1/KPNB1	29
GO:0045216	cell-cell junction organization	22/1068	200/18722	0.00242467509144678	0.012261993245967	CD9/LIMS1/MTDH/CSF1R/ACTB/PECAM1/FLNA/RHOA/VEGFA/TGFB1/CSK/TLN1/IL1B/NUMB/TGFBR1/PAK2/ROCK1/APC/ADAM10/CDC42/PLEC/RAB13	22
GO:0070227	lymphocyte apoptotic process	11/1068	72/18722	0.00243280117164291	0.0122800702733257	CD74/LGALS3/LGALS9/HIF1A/LYN/BTK/ADAM8/BCL6/TSC22D3/FNIP1/BAX	11
GO:1901880	negative regulation of protein depolymerization	11/1068	72/18722	0.00243280117164291	0.0122800702733257	CAPG/TWF2/CIB1/ARHGEF2/CAPZA2/CAPZA1/APC/GSN/FLII/TAOK1/CAPZB	11
GO:1990748	cellular detoxification	15/1068	116/18722	0.00246379801509045	0.0124249103639515	APOE/GPX1/SOD2/ALOX5AP/CD36/ALDH1A1/MGST1/PTGS1/GLRX/LTC4S/RDH11/GPX4/MGST2/AKR1A1/GSTO1	15
GO:0051496	positive regulation of stress fiber assembly	9/1068	52/18722	0.0024741568871938	0.0124594847294641	GPR65/CCDC88A/RHOA/RAC1/RGCC/TGFBR1/PAK1/CDC42/S100A10	9
GO:0046847	filopodium assembly	10/1068	62/18722	0.00250759056105043	0.0124594847294641	RHOQ/FGD4/TRPM2/ARAP1/RALA/TGFBR1/ARF6/CDC42/PIK3R1/CAPZB	10
GO:0002327	immature B cell differentiation	4/1068	11/18722	0.00251452536515686	0.0124594847294641	SPI1/ATM/FNIP1/IRF2BP2	4
GO:0002604	regulation of dendritic cell antigen processing and presentation	4/1068	11/18722	0.00251452536515686	0.0124594847294641	CD74/CD68/SLC11A1/FGL2	4
GO:0002645	positive regulation of tolerance induction	4/1068	11/18722	0.00251452536515686	0.0124594847294641	LILRB4/TGFBR2/LILRB2/IRAK3	4
GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	4/1068	11/18722	0.00251452536515686	0.0124594847294641	ATP1B1/BAX/ATP1B3/ATP1A1	4
GO:0010887	negative regulation of cholesterol storage	4/1068	11/18722	0.00251452536515686	0.0124594847294641	TREM2/NR1H3/ABCG1/ABCA1	4
GO:0019372	lipoxygenase pathway	4/1068	11/18722	0.00251452536515686	0.0124594847294641	GPX1/ALOX5AP/ALOX5/GPX4	4
GO:0032493	response to bacterial lipoprotein	4/1068	11/18722	0.00251452536515686	0.0124594847294641	CD14/CD36/TLR2/TLR1	4
GO:0034115	negative regulation of heterotypic cell-cell adhesion	4/1068	11/18722	0.00251452536515686	0.0124594847294641	MBP/KLF4/MYADM/WNK1	4
GO:0035457	cellular response to interferon-alpha	4/1068	11/18722	0.00251452536515686	0.0124594847294641	IFIT3/IFIT2/AXL/IFNAR1	4
GO:0042167	heme catabolic process	4/1068	11/18722	0.00251452536515686	0.0124594847294641	HMOX1/SLCO2B1/BLVRB/BLVRA	4
GO:0046149	pigment catabolic process	4/1068	11/18722	0.00251452536515686	0.0124594847294641	HMOX1/SLCO2B1/BLVRB/BLVRA	4
GO:0046643	regulation of gamma-delta T cell activation	4/1068	11/18722	0.00251452536515686	0.0124594847294641	NCKAP1L/PTPRC/SYK/LILRB1	4
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	4/1068	11/18722	0.00251452536515686	0.0124594847294641	MBP/KLF4/MYADM/WNK1	4
GO:0097048	dendritic cell apoptotic process	4/1068	11/18722	0.00251452536515686	0.0124594847294641	LGALS9/LYN/AXL/LILRB1	4
GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	4/1068	11/18722	0.00251452536515686	0.0124594847294641	CD36/TLR4/GBP5/MYD88	4
GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	4/1068	11/18722	0.00251452536515686	0.0124594847294641	LAPTM5/HSPA1A/CASP1/ADAM17	4
GO:2000668	regulation of dendritic cell apoptotic process	4/1068	11/18722	0.00251452536515686	0.0124594847294641	LGALS9/LYN/AXL/LILRB1	4
GO:0035303	regulation of dephosphorylation	16/1068	128/18722	0.00255550802860375	0.0126509369929779	PLEK/LGALS3/MEF2C/NCKAP1L/PTPRC/GNAI2/CD300A/TGFB1/LILRB2/JAK2/CD33/CALM3/ROCK1/PPP1R15A/PPP2R3C/BOD1L1	16
GO:0014002	astrocyte development	8/1068	43/18722	0.00265755168676782	0.0131287841687996	VIM/TREM2/C1QA/GRN/C5AR1/IFNGR1/TLR4/LRP1	8
GO:0042088	T-helper 1 type immune response	8/1068	43/18722	0.00265755168676782	0.0131287841687996	HLA-DRB1/HAVCR2/IL18/SLC11A1/TLR4/SPN/STAT6/IL1B	8
GO:0046578	regulation of Ras protein signal transduction	21/1068	189/18722	0.00266303933122891	0.0131287841687996	APOE/GPR65/FBP1/ARHGDIB/TIMP2/LPAR6/MYO9B/NOTCH2/CYTH1/CYTH4/BCL6/ARHGEF2/GABARAP/RAC1/ABCA1/NUP62/ARHGAP24/ARF6/AKAP13/FLOT1/ARHGDIA	21
GO:0030851	granulocyte differentiation	7/1068	34/18722	0.00266906527671853	0.0131287841687996	C1QC/SPI1/EVI2B/RUNX1/INPP5D/CEBPA/HCLS1	7
GO:0034383	low-density lipoprotein particle clearance	7/1068	34/18722	0.00266906527671853	0.0131287841687996	TREM2/LIPA/HMOX1/CD36/SOAT1/NCEH1/CSK	7
GO:0044319	wound healing, spreading of cells	7/1068	34/18722	0.00266906527671853	0.0131287841687996	CD44/FLNA/RHOA/HBEGF/ITGA5/ADAM17/ARHGAP24	7
GO:0090505	epiboly involved in wound healing	7/1068	34/18722	0.00266906527671853	0.0131287841687996	CD44/FLNA/RHOA/HBEGF/ITGA5/ADAM17/ARHGAP24	7
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	11/1068	73/18722	0.00272001706465967	0.0133672241173985	PLAUR/CCDC88A/HBEGF/NCF1/RHBDF2/PTPRJ/DUSP3/ADAM17/SHKBP1/NUP62/RAB7A	11
GO:0032388	positive regulation of intracellular transport	22/1068	202/18722	0.00274395709361508	0.0134004154511353	CD81/ITGB2/SORL1/MSN/FLNA/CIB1/OAZ1/PRNP/TGFB1/ITGAM/JAK2/PLK3/RAB29/IL1B/PAK1/TMEM30A/HCLS1/CDC42/UBE2D3/SCP2/KIF5B/PIK3R1	22
GO:0030730	sequestering of triglyceride	5/1068	18/18722	0.00274663815584797	0.0134004154511353	TREM2/PLIN2/LPL/OSBPL8/IL1B	5
GO:0034433	steroid esterification	5/1068	18/18722	0.00274663815584797	0.0134004154511353	APOE/APOC1/SOAT1/ABCG1/ACAT1	5
GO:0034434	sterol esterification	5/1068	18/18722	0.00274663815584797	0.0134004154511353	APOE/APOC1/SOAT1/ABCG1/ACAT1	5
GO:0034435	cholesterol esterification	5/1068	18/18722	0.00274663815584797	0.0134004154511353	APOE/APOC1/SOAT1/ABCG1/ACAT1	5
GO:0035743	CD4-positive, alpha-beta T cell cytokine production	5/1068	18/18722	0.00274663815584797	0.0134004154511353	CD81/IL18/RSAD2/DENND1B/IL1B	5
GO:0060008	Sertoli cell differentiation	5/1068	18/18722	0.00274663815584797	0.0134004154511353	FLNA/FNDC3A/ARID4A/HSD17B4/RAB13	5
GO:0097709	connective tissue replacement	5/1068	18/18722	0.00274663815584797	0.0134004154511353	TIMP1/HIF1A/TGFB1/RUNX1/ROCK1	5
GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	16/1068	129/18722	0.00276686362383483	0.0134868980254858	CTSD/LAPTM5/CTSH/PYCARD/CLEC7A/LGALS9/RHOA/SYK/CASP1/BID/JAK2/TNFSF10/RPS27L/DAPK1/GSN/BAX	16
GO:0006090	pyruvate metabolic process	14/1068	106/18722	0.00277690266237762	0.0134992493389096	NUPR1/SDS/FBP1/HIF1A/ME2/PDK4/P2RX7/DDIT4/PRKAG2/ADPGK/STAT3/LDHA/PGK1/PKM	14
GO:0006906	vesicle fusion	14/1068	106/18722	0.00277690266237762	0.0134992493389096	CORO1A/SAMD9/STX10/STX6/RAB8B/STX4/STX12/ARL8B/STX7/CHMP3/RAB8A/KIF5B/RAB7A/RAB13	14
GO:0046822	regulation of nucleocytoplasmic transport	14/1068	106/18722	0.00277690266237762	0.0134992493389096	IFI27/CD36/FLNA/NUP214/MX2/SP100/TGFB1/MDFIC/JAK2/IL1B/NUP62/HCLS1/UHMK1/PIK3R1	14
GO:0031669	cellular response to nutrient levels	23/1068	215/18722	0.00280194332548179	0.0136087184377135	CD68/GLUL/IFI16/HMOX1/JUN/UPP1/LAMP2/UCP2/LPL/USF2/PDK4/RRAGD/NAMPT/LRRK2/PRKAG2/GABARAP/CDKN1A/EIF2AK2/SESN3/MAX/KLF10/FNIP1/ATF3	23
GO:0001562	response to protozoan	6/1068	26/18722	0.00291881147959775	0.0140749836853525	CLEC7A/SLC11A1/GBP4/IRF8/GBP2/MYD88	6
GO:0002407	dendritic cell chemotaxis	6/1068	26/18722	0.00291881147959775	0.0140749836853525	CXCR4/SPI1/LGALS9/GPR183/CCR1/TRPM2	6
GO:0002418	immune response to tumor cell	6/1068	26/18722	0.00291881147959775	0.0140749836853525	HLA-DRB1/HLA-A/HAVCR2/IL4I1/AHR/MR1	6
GO:0032515	negative regulation of phosphoprotein phosphatase activity	6/1068	26/18722	0.00291881147959775	0.0140749836853525	LGALS3/NCKAP1L/GNAI2/ROCK1/PPP1R15A/BOD1L1	6
GO:0032682	negative regulation of chemokine production	6/1068	26/18722	0.00291881147959775	0.0140749836853525	LGALS9/LILRB4/OAS1/SIRPA/KLF4/OAS3	6
GO:0033598	mammary gland epithelial cell proliferation	6/1068	26/18722	0.00291881147959775	0.0140749836853525	GPX1/ID2/STAT6/CEBPB/RTN4/BAX	6
GO:0070102	interleukin-6-mediated signaling pathway	6/1068	26/18722	0.00291881147959775	0.0140749836853525	SPI1/JAK1/JAK2/IL6R/STAT3/CEBPA	6
GO:2000108	positive regulation of leukocyte apoptotic process	6/1068	26/18722	0.00291881147959775	0.0140749836853525	LGALS9/MEF2C/LYN/ADAM8/FNIP1/BAX	6
GO:0060537	muscle tissue development	37/1068	403/18722	0.00300031210502532	0.014455075105997	GPX1/HAMP/NUPR1/FOS/MEF2A/SLC8A1/ID2/MEF2C/ARRB2/RB1/VAMP5/GPCPD1/RHOA/VEGFA/TGFB1/ENG/TGFBR2/RUNX1/NOTCH2/SAP30/FOXN2/BTG2/PRKAR1A/DDX5/TGFBR1/PAK1/SKI/NR4A1/AKAP13/CDC42/RGS2/ATF3/FLOT1/MYL6/EGR1/ZFAND5/PLEC	37
GO:0010822	positive regulation of mitochondrion organization	11/1068	74/18722	0.00303395980576278	0.0146041455057056	TREM2/PLAUR/PYCARD/CHCHD10/HIF1A/BID/TNFSF10/RALA/DDHD1/BAX/PPIF	11
GO:1903573	negative regulation of response to endoplasmic reticulum stress	8/1068	44/18722	0.00308871801586933	0.0148544763044839	TMBIM6/HSPA1A/ALOX5/NR1H3/LRRK2/GRINA/PPP1R15A/HERPUD1	8
GO:0006631	fatty acid metabolic process	36/1068	390/18722	0.00310200588184573	0.0149050968285303	APOC1/CD74/FABP5/GPX1/C3/ASAH1/ALOX5AP/CD36/LPL/PDK4/ALOX5/TBXAS1/SCD/ACAA2/ABHD2/AOAH/LPGAT1/PTGS1/NR1H3/LTC4S/PRKAG2/ACSL1/GPX4/IL1B/SGPL1/QKI/ACAT1/ABHD12/HACD4/CPT1A/TNFRSF1A/ALKBH7/PLA2G15/ACSL4/SCP2/HSD17B4	36
GO:0010769	regulation of cell morphogenesis involved in differentiation	13/1068	96/18722	0.00310534590193031	0.0149078705398718	LIMS1/GBP1/ACTR2/FLNA/CORO1C/CIB1/PREX1/MYADM/RAC1/CDC42/RCC2/DBNL/S100A10	13
GO:0010507	negative regulation of autophagy	12/1068	85/18722	0.00311483038604531	0.0149401109005338	TREM2/NUPR1/TSPO/HMOX1/HGF/CTSA/IL10RA/NAMPT/LRRK2/MCL1/STAT3/TAB2	12
GO:0034405	response to fluid shear stress	7/1068	35/18722	0.00317479574239584	0.0152007079201135	MEF2C/KLF4/KLF2/PTK2B/ADAM9/ABCA1/PLEC	7
GO:0090504	epiboly	7/1068	35/18722	0.00317479574239584	0.0152007079201135	CD44/FLNA/RHOA/HBEGF/ITGA5/ADAM17/ARHGAP24	7
GO:0001885	endothelial cell development	10/1068	64/18722	0.00318806137614106	0.0152371826268	GPX1/MSN/PECAM1/RAP1A/VEGFA/MYADM/MYD88/IL1B/TNFRSF1A/ROCK1	10
GO:0070542	response to fatty acid	10/1068	64/18722	0.00318806137614106	0.0152371826268	CD36/UCP2/LPL/PDK4/TLR2/TBXAS1/SCD/PTAFR/ACSL1/CPT1A	10
GO:0060348	bone development	22/1068	205/18722	0.00328889293991071	0.015705191419255	TYROBP/ACP5/SNX10/MEF2C/PTPRC/RHOA/LILRB1/PTGER4/ENG/TGFBR2/PTPN6/NOTCH2/SH2B3/FLI1/VKORC1/ABI1/ATP6AP1/DHRS3/FOXN3/ZNF385A/SKI/AKAP13	22
GO:0007033	vacuole organization	20/1068	180/18722	0.0033201377866854	0.0158403744446989	LAPTM5/GRN/NUPR1/PPT1/TPP1/VMP1/ATP6AP2/CORO1A/TCIRG1/LRRK2/SCARB2/GABARAP/ACP2/ABCA1/STX12/ARL8B/ATG3/GAA/CHMP3/RAB7A	20
GO:0033077	T cell differentiation in thymus	11/1068	75/18722	0.00337638085975242	0.0160944797873004	CD74/B2M/MAFB/ZFP36L2/ZFP36L1/PTPRC/DOCK2/ADAM8/MR1/IL1B/ADAM17	11
GO:0014909	smooth muscle cell migration	13/1068	97/18722	0.00340332603168402	0.0161943097592301	AIF1/SORL1/DOCK4/MEF2C/RHOA/TLR4/PLAU/GNA13/LRP1/IQGAP1/PAK1/ARPC5/S100A11	13
GO:0120162	positive regulation of cold-induced thermogenesis	13/1068	97/18722	0.00340332603168402	0.0161943097592301	FABP5/CXCR4/IL18/CD36/UCP2/SYK/VEGFA/SCD/JAK2/ACSL1/STAT6/CEBPB/APC	13
GO:0016482	cytosolic transport	19/1068	168/18722	0.00340665505894655	0.0161958684564543	LAPTM5/SORL1/MSN/ACTR2/FLNA/CORO1A/VPS13C/STX10/TANC2/LRRK2/STX6/GGA1/RAB29/ARL8B/DENND5A/LAMP1/CHMP3/KIF5B/RAB7A	19
GO:0035023	regulation of Rho protein signal transduction	12/1068	86/18722	0.00343656020580286	0.0163236609775636	APOE/GPR65/ARHGDIB/LPAR6/MYO9B/BCL6/ARHGEF2/RAC1/ABCA1/AKAP13/FLOT1/ARHGDIA	12
GO:0009267	cellular response to starvation	18/1068	156/18722	0.00346893147445109	0.0164629324856096	GLUL/IFI16/JUN/UPP1/LAMP2/UCP2/PDK4/RRAGD/LRRK2/PRKAG2/GABARAP/CDKN1A/EIF2AK2/SESN3/MAX/KLF10/FNIP1/ATF3	18
GO:0017038	protein import	22/1068	206/18722	0.00348959144692886	0.0165464283371073	APOE/TXNIP/CD36/LAMP2/FLNA/NUP214/SYK/TGFB1/MDFIC/JAK2/LRRK2/CDKN1A/RAB8B/STAT3/KPNA3/NFKBIA/NUP62/HCLS1/RANBP2/APPL1/PIK3R1/KPNB1	22
GO:0007039	protein catabolic process in the vacuole	5/1068	19/18722	0.00355451557159757	0.0167586304973807	CD81/TPP1/LAMP2/TCIRG1/LRP1	5
GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	5/1068	19/18722	0.00355451557159757	0.0167586304973807	RGS10/GNAI2/GNA15/GNB1/GNAQ	5
GO:0032695	negative regulation of interleukin-12 production	5/1068	19/18722	0.00355451557159757	0.0167586304973807	ACP5/ARRB2/LILRB1/TLR8/IRAK3	5
GO:1900221	regulation of amyloid-beta clearance	5/1068	19/18722	0.00355451557159757	0.0167586304973807	APOE/TREM2/IFNGR1/LRP1/ROCK1	5
GO:0035307	positive regulation of protein dephosphorylation	8/1068	45/18722	0.00357235780742761	0.0167586304973807	PTPRC/CD300A/TGFB1/LILRB2/JAK2/CD33/CALM3/PPP1R15A	8
GO:0071354	cellular response to interleukin-6	8/1068	45/18722	0.00357235780742761	0.0167586304973807	HAMP/SPI1/JAK1/JAK2/SELPLG/IL6R/STAT3/CEBPA	8
GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	8/1068	45/18722	0.00357235780742761	0.0167586304973807	CHCHD10/HSPA1A/ACAA2/BID/BNIP3L/SLC35F6/BLOC1S2/BAX	8
GO:1904646	cellular response to amyloid-beta	8/1068	45/18722	0.00357235780742761	0.0167586304973807	TREM2/LGMN/CD36/TLR4/PRNP/NAMPT/ITGA4/LRP1	8
GO:0032967	positive regulation of collagen biosynthetic process	6/1068	27/18722	0.00357432889133067	0.0167586304973807	VIM/ARRB2/TGFB1/ENG/RUNX1/RGCC	6
GO:0060142	regulation of syncytium formation by plasma membrane fusion	6/1068	27/18722	0.00357432889133067	0.0167586304973807	TYROBP/TREM2/CD53/PLEKHO1/ADAM9/FLOT1	6
GO:0071624	positive regulation of granulocyte chemotaxis	6/1068	27/18722	0.00357432889133067	0.0167586304973807	CD74/C5AR1/C3AR1/NCKAP1L/CAMK1D/RAC1	6
GO:0032414	positive regulation of ion transmembrane transporter activity	14/1068	109/18722	0.00359780998120095	0.0167586304973807	TMSB4X/TREM2/CTSS/IFNGR2/VMP1/PTAFR/KCNE3/ATP1B1/GLRX/CALM3/GSTO1/WNK1/KIF5B/ATP1B3	14
GO:0002664	regulation of T cell tolerance induction	4/1068	12/18722	0.00360267075184611	0.0167586304973807	HLA-B/LILRB4/TGFBR2/LILRB2	4
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	4/1068	12/18722	0.00360267075184611	0.0167586304973807	C3/CD81/HLA-E/BTK	4
GO:0006787	porphyrin-containing compound catabolic process	4/1068	12/18722	0.00360267075184611	0.0167586304973807	HMOX1/SLCO2B1/BLVRB/BLVRA	4
GO:0033015	tetrapyrrole catabolic process	4/1068	12/18722	0.00360267075184611	0.0167586304973807	HMOX1/SLCO2B1/BLVRB/BLVRA	4
GO:0042117	monocyte activation	4/1068	12/18722	0.00360267075184611	0.0167586304973807	LILRB4/CD33/ADAM9/ADAM10	4
GO:0043380	regulation of memory T cell differentiation	4/1068	12/18722	0.00360267075184611	0.0167586304973807	HLA-DRA/HLA-DRB1/FGL2/BCL6	4
GO:0070572	positive regulation of neuron projection regeneration	4/1068	12/18722	0.00360267075184611	0.0167586304973807	GRN/HGF/FLNA/LRP1	4
GO:0070586	cell-cell adhesion involved in gastrulation	4/1068	12/18722	0.00360267075184611	0.0167586304973807	MBP/KLF4/MYADM/WNK1	4
GO:0140289	protein mono-ADP-ribosylation	4/1068	12/18722	0.00360267075184611	0.0167586304973807	PARP9/PARP12/PARP4/PARP14	4
GO:2001204	regulation of osteoclast development	4/1068	12/18722	0.00360267075184611	0.0167586304973807	TYROBP/LILRB1/NOTCH2/ATP6AP1	4
GO:1904019	epithelial cell apoptotic process	15/1068	121/18722	0.00371276441067675	0.0172558800689162	NUPR1/ZFP36/HMOX1/ZFP36L1/ARRB2/RB1/TGFBR2/BID/JAK2/ITGA4/STK4/TNFAIP3/RGCC/GSN/ARF6	15
GO:0043473	pigmentation	13/1068	98/18722	0.00372411217007357	0.0172788557779166	ZEB2/CD63/RAB32/MEF2C/ATP6AP2/MYO5A/MITF/BLOC1S1/MFSD12/RAB29/BLOC1S2/HPS3/BAX	13
GO:1902882	regulation of response to oxidative stress	13/1068	98/18722	0.00372411217007357	0.0172788557779166	GPX1/TREM2/SOD2/CD36/HIF1A/HGF/ALOX5/TLR4/MCTP1/TRPM2/LRRK2/MCL1/SESN3	13
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	11/1068	76/18722	0.00374908587353136	0.0173565402330298	CD74/NUPR1/CD44/PYCARD/IFI16/DDIT4/CDKN1A/RPS27L/DDX5/ZNF385A/BAX	11
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	7/1068	36/18722	0.00375050517266729	0.0173565402330298	HLA-DRB1/HIF1A/RAC1/ABCG1/LRP1/STX4/KIF5B	7
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	7/1068	36/18722	0.00375050517266729	0.0173565402330298	PLAUR/CCDC88A/HBEGF/NCF1/ADAM17/SHKBP1/NUP62	7
GO:0001701	in utero embryonic development	34/1068	367/18722	0.0037574165063923	0.0173736242232158	SKIL/GRB2/JUNB/HIF1A/ZFP36L1/MBNL1/LPAR6/CMTM3/YBX1/MGAT1/ZMIZ1/KLF4/VEGFA/ST14/TGFBR2/VASH1/PRDM1/NOTCH2/TANC2/KLF2/PTPN18/STK4/SCO2/RNASEH2B/SLC30A1/SOCS3/CEBPB/HM13/TGFBR1/RTN4/CEBPA/ADAM10/BRK1/ZFAND5	34
GO:0051260	protein homooligomerization	20/1068	182/18722	0.00376803762331036	0.0174078176501564	B2M/SOD2/SAMHD1/KCTD12/ALOX5AP/PYCARD/RNF213/PRNP/GLS/GBP5/TRPM2/EHD4/VASP/MCOLN1/HPRT1/ATL3/NINJ1/RNF135/SHKBP1/MICU1	20
GO:0051262	protein tetramerization	12/1068	87/18722	0.00378457256889581	0.0174394138187547	HLA-DRB1/B2M/SOD2/SAMHD1/GLS/GBP5/TRPM2/VASP/STK4/MCOLN1/HPRT1/OXA1L	12
GO:1901879	regulation of protein depolymerization	12/1068	87/18722	0.00378457256889581	0.0174394138187547	CAPG/PLEK/TWF2/CIB1/ARHGEF2/CAPZA2/CAPZA1/APC/GSN/FLII/TAOK1/CAPZB	12
GO:1903578	regulation of ATP metabolic process	12/1068	87/18722	0.00378457256889581	0.0174394138187547	TMSB4X/TREM2/NUPR1/TSPO/FBP1/HIF1A/RHOA/P2RX7/DDIT4/PRKAG2/STAT3/PPIF	12
GO:0090174	organelle membrane fusion	14/1068	110/18722	0.00391176033697488	0.0180101184115328	CORO1A/SAMD9/STX10/STX6/RAB8B/STX4/STX12/ARL8B/STX7/CHMP3/RAB8A/KIF5B/RAB7A/RAB13	14
GO:0045600	positive regulation of fat cell differentiation	10/1068	66/18722	0.00400785815658108	0.0184368308720473	ZFP36/ID2/ZFP36L1/LPL/METRNL/CREBL2/STK4/CEBPB/CEBPA/ZNF385A	10
GO:0042552	myelination	16/1068	134/18722	0.00405252144129292	0.0186264103042731	TYMP/CD9/CXCR4/CTSC/HGF/TLR2/ITGAX/MBP/TNFRSF1B/PMP22/GALC/CYFIP1/QKI/SKI/ACER3/PLEC	16
GO:0010828	positive regulation of glucose transmembrane transport	8/1068	46/18722	0.00411258417556786	0.0188703267103437	C3/MEF2A/RHOQ/RAP1A/CREBL2/OSBPL8/APPL1/PIK3R1	8
GO:2000107	negative regulation of leukocyte apoptotic process	8/1068	46/18722	0.00411258417556786	0.0188703267103437	CD74/HIF1A/AXL/LILRB1/IRF7/BCL6/TSC22D3/HCLS1	8
GO:1904645	response to amyloid-beta	9/1068	56/18722	0.00415736602280412	0.0190249231004421	TREM2/LGMN/CD36/TLR4/PRNP/NAMPT/ITGA4/MMP2/LRP1	9
GO:0030101	natural killer cell activation	12/1068	88/18722	0.00416037977363264	0.0190249231004421	TYROBP/HLA-E/HAVCR2/IL18/HLA-F/PTPRC/AXL/CORO1A/SLAMF7/PRDM1/FGR/LAMP1	12
GO:0050829	defense response to Gram-negative bacterium	12/1068	88/18722	0.00416037977363264	0.0190249231004421	TREM2/LYZ/PYCARD/SLC11A1/CD4/RNASE6/TNFRSF14/CASP1/TLR4/TREM1/IL6R/MR1	12
GO:0070098	chemokine-mediated signaling pathway	12/1068	88/18722	0.00416037977363264	0.0190249231004421	TREM2/CCL3/CCL3L3/CXCR4/HIF1A/CCL4/CIB1/CCR1/CCRL2/SH2B3/PTK2B/WNK1	12
GO:0002675	positive regulation of acute inflammatory response	6/1068	28/18722	0.00433312667408576	0.0197646251338688	C3/HLA-E/ALOX5AP/BTK/ADAM8/IL1B	6
GO:0010714	positive regulation of collagen metabolic process	6/1068	28/18722	0.00433312667408576	0.0197646251338688	VIM/ARRB2/TGFB1/ENG/RUNX1/RGCC	6
GO:0090200	positive regulation of release of cytochrome c from mitochondria	6/1068	28/18722	0.00433312667408576	0.0197646251338688	PLAUR/PYCARD/BID/TNFSF10/BAX/PPIF	6
GO:0043029	T cell homeostasis	7/1068	37/18722	0.00440212962146536	0.0200454780062676	LGALS9/NCKAP1L/CORO1A/TCIRG1/TSC22D3/PPP2R3C/BAX	7
GO:0043368	positive T cell selection	7/1068	37/18722	0.00440212962146536	0.0200454780062676	CD74/PTPRC/DOCK2/IL6R/SPN/STAT6/STAT3	7
GO:0002115	store-operated calcium entry	5/1068	20/18722	0.0045196662414104	0.0204770101080189	CD84/HOMER3/ORAI2/ORAI3/SARAF	5
GO:0002834	regulation of response to tumor cell	5/1068	20/18722	0.0045196662414104	0.0204770101080189	HLA-DRB1/HAVCR2/IL4I1/AHR/MR1	5
GO:0002837	regulation of immune response to tumor cell	5/1068	20/18722	0.0045196662414104	0.0204770101080189	HLA-DRB1/HAVCR2/IL4I1/AHR/MR1	5
GO:0006883	cellular sodium ion homeostasis	5/1068	20/18722	0.0045196662414104	0.0204770101080189	SLC8A1/ATP1B1/SLC1A3/ATP1B3/ATP1A1	5
GO:0043555	regulation of translation in response to stress	5/1068	20/18722	0.0045196662414104	0.0204770101080189	RPS6KA1/EIF2AK2/RPS6KA3/PPP1R15A/DNAJC3	5
GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	5/1068	20/18722	0.0045196662414104	0.0204770101080189	TMBIM6/HSPA1A/LRRK2/GRINA/HERPUD1	5
GO:0043433	negative regulation of DNA-binding transcription factor activity	20/1068	185/18722	0.00453328925578225	0.0205215006914438	TMSB4X/NUPR1/PYCARD/HMOX1/SPI1/ID2/HAVCR2/ARRB2/RB1/FLNA/KLF4/PRNP/SP100/ADORA3/IRAK1/NFKBIE/IRAK3/TNFAIP3/NFKBIA/BHLHE40	20
GO:0014910	regulation of smooth muscle cell migration	12/1068	89/18722	0.00456553404124569	0.0206501439116193	AIF1/SORL1/DOCK4/MEF2C/RHOA/TLR4/PLAU/GNA13/LRP1/IQGAP1/PAK1/S100A11	12
GO:0032371	regulation of sterol transport	11/1068	78/18722	0.00459282706357877	0.0207214839758119	APOE/APOC1/TREM2/TSPO/PLTP/NR1H3/ABCG1/LRP1/NFKBIA/ABCA1/SCP2	11
GO:0032374	regulation of cholesterol transport	11/1068	78/18722	0.00459282706357877	0.0207214839758119	APOE/APOC1/TREM2/TSPO/PLTP/NR1H3/ABCG1/LRP1/NFKBIA/ABCA1/SCP2	11
GO:0070373	negative regulation of ERK1 and ERK2 cascade	11/1068	78/18722	0.00459282706357877	0.0207214839758119	DUSP1/PTPRC/GBP1/LYN/SIRPA/TLR4/KLF4/CSK/SPRED1/DUSP3/ATF3	11
GO:0097237	cellular response to toxic substance	15/1068	124/18722	0.00468323530879262	0.0210661508821739	APOE/GPX1/SOD2/ALOX5AP/CD36/ALDH1A1/MGST1/PTGS1/GLRX/LTC4S/RDH11/GPX4/MGST2/AKR1A1/GSTO1	15
GO:0007272	ensheathment of neurons	16/1068	136/18722	0.00468789334200101	0.0210661508821739	TYMP/CD9/CXCR4/CTSC/HGF/TLR2/ITGAX/MBP/TNFRSF1B/PMP22/GALC/CYFIP1/QKI/SKI/ACER3/PLEC	16
GO:0008366	axon ensheathment	16/1068	136/18722	0.00468789334200101	0.0210661508821739	TYMP/CD9/CXCR4/CTSC/HGF/TLR2/ITGAX/MBP/TNFRSF1B/PMP22/GALC/CYFIP1/QKI/SKI/ACER3/PLEC	16
GO:0098876	vesicle-mediated transport to the plasma membrane	16/1068	136/18722	0.00468789334200101	0.0210661508821739	SORL1/VAMP5/GGA2/CSK/EHD4/STX6/DENND1B/ATP2C1/GGA1/ACAP2/ARF6/ARL4C/RAB10/RAB8A/RAB7A/RAB13	16
GO:0006949	syncytium formation	9/1068	57/18722	0.00469264517427224	0.0210661508821739	TYROBP/TREM2/CD9/CD81/CD53/PLEKHO1/ERCC1/ADAM9/FLOT1	9
GO:0051289	protein homotetramerization	9/1068	57/18722	0.00469264517427224	0.0210661508821739	B2M/SOD2/SAMHD1/GLS/GBP5/TRPM2/VASP/MCOLN1/HPRT1	9
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	8/1068	47/18722	0.00471360903985728	0.0211075803975684	LAPTM5/PYCARD/SYK/HSPA1A/CASP1/CARD16/TNFAIP3/ADAM17	8
GO:0061001	regulation of dendritic spine morphogenesis	8/1068	47/18722	0.00471360903985728	0.0211075803975684	ACTR2/ABI3/TANC2/LRRK2/CFL1/ADAM10/UBE3A/DBNL	8
GO:0072583	clathrin-dependent endocytosis	8/1068	47/18722	0.00471360903985728	0.0211075803975684	BMP2K/SIGLEC1/ITGA4/ITSN2/SMAP1/CANX/FCHO2/PICALM	8
GO:0007346	regulation of mitotic cell cycle	40/1068	457/18722	0.00479588807176535	0.021458218934698	GPNMB/AIF1/LGMN/ZFP36L2/DUSP1/ID2/TIMP2/ZFP36L1/RB1/SDCBP/TAOK3/EIF4EBP1/KLF4/TGFB1/BID/PTPN6/PLK3/SLFN11/BCL6/CDKN1A/KMT2E/BTG2/RNASEH2B/IL1B/RPS27L/RGCC/BTG1/ATM/DUSP3/IQGAP1/FOXN3/ADAM17/APC/NUP62/DYNC1LI1/CDC42/TAOK1/RCC2/PSME2/APPL1	40
GO:0032368	regulation of lipid transport	17/1068	149/18722	0.00496338864845135	0.0219865935844623	APOE/APOC1/SPP1/TREM2/TSPO/RETN/SYK/PLTP/NR1H3/ACSL1/IL1B/ABCG1/LRP1/NFKBIA/ABCA1/TMEM30A/SCP2	17
GO:0002430	complement receptor mediated signaling pathway	4/1068	13/18722	0.00497102375334395	0.0219865935844623	FPR3/C5AR1/C3AR1/FPR1	4
GO:0002551	mast cell chemotaxis	4/1068	13/18722	0.00497102375334395	0.0219865935844623	VEGFA/RIN3/RAC1/VEGFB	4
GO:0010745	negative regulation of macrophage derived foam cell differentiation	4/1068	13/18722	0.00497102375334395	0.0219865935844623	NR1H3/ABCG1/NFKBIA/ABCA1	4
GO:0032494	response to peptidoglycan	4/1068	13/18722	0.00497102375334395	0.0219865935844623	TREM2/C5AR1/IRAK3/MYD88	4
GO:0033700	phospholipid efflux	4/1068	13/18722	0.00497102375334395	0.0219865935844623	APOE/APOC1/ABCG1/ABCA1	4
GO:0034112	positive regulation of homotypic cell-cell adhesion	4/1068	13/18722	0.00497102375334395	0.0219865935844623	LGALS1/PLAUR/JAK1/JAK2	4
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	4/1068	13/18722	0.00497102375334395	0.0219865935844623	TREM2/LYN/LILRA2/TNFAIP3	4
GO:0043379	memory T cell differentiation	4/1068	13/18722	0.00497102375334395	0.0219865935844623	HLA-DRA/HLA-DRB1/FGL2/BCL6	4
GO:0060100	positive regulation of phagocytosis, engulfment	4/1068	13/18722	0.00497102375334395	0.0219865935844623	TREM2/C3/CD36/NCKAP1L	4
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	4/1068	13/18722	0.00497102375334395	0.0219865935844623	HIF1A/VEGFA/BACH1/EGR1	4
GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	4/1068	13/18722	0.00497102375334395	0.0219865935844623	SKIL/PEA15/STK4/ATF3	4
GO:1903054	negative regulation of extracellular matrix organization	4/1068	13/18722	0.00497102375334395	0.0219865935844623	CST3/TNFRSF1B/TGFB1/TNFRSF1A	4
GO:1905155	positive regulation of membrane invagination	4/1068	13/18722	0.00497102375334395	0.0219865935844623	TREM2/C3/CD36/NCKAP1L	4
GO:0099175	regulation of postsynapse organization	12/1068	90/18722	0.00500162571070124	0.0220826392841736	APOE/SRGN/ACTR2/PRNP/ABI3/LILRB2/TANC2/LRRK2/CFL1/ADAM10/UBE3A/DBNL	12
GO:1904705	regulation of vascular associated smooth muscle cell proliferation	12/1068	90/18722	0.00500162571070124	0.0220826392841736	SOD2/HMOX1/JUN/MEF2C/GNAI2/RHOA/JAK2/NQO2/MMP2/CDKN1A/GNA13/PAK1	12
GO:0007584	response to nutrient	19/1068	174/18722	0.00500501627956715	0.0220826392841736	SPP1/HAMP/TSPO/SOD2/STAT1/HMOX1/SLC8A1/CYBB/GNAI2/LPL/USF2/KYNU/C2/TGFBR2/ACSL1/ERCC1/LDHA/ABCA1/ACSL4	19
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	11/1068	79/18722	0.00506772328261542	0.0223228039453003	TREM2/IL18/HCST/HGF/PIK3AP1/NCF1/PTPN6/JAK2/FGR/HCLS1/UBE3A	11
GO:0032272	negative regulation of protein polymerization	11/1068	79/18722	0.00506772328261542	0.0223228039453003	TMSB4X/CAPG/TMSB10/TWF2/MYADM/CAPZA2/CAPZA1/GSN/FLII/CAPZB/PFN1	11
GO:0048246	macrophage chemotaxis	7/1068	38/18722	0.00513571181792767	0.0225854123631114	CCL3/C5AR1/LGALS3/CSF1R/C3AR1/CKLF/PTK2B	7
GO:0098926	postsynaptic signal transduction	7/1068	38/18722	0.00513571181792767	0.0225854123631114	RGS10/GNAI2/JAK2/GNA15/STAT3/GNB1/GNAQ	7
GO:0090025	regulation of monocyte chemotaxis	6/1068	29/18722	0.00520440234531964	0.0228502482142756	AIF1/LGMN/DUSP1/PLA2G7/LYN/CCR1	6
GO:1902430	negative regulation of amyloid-beta formation	6/1068	29/18722	0.00520440234531964	0.0228502482142756	APOE/SORL1/PRNP/RTN4/ROCK1/RTN3	6
GO:0009895	negative regulation of catabolic process	30/1068	320/18722	0.00527292625389061	0.023132284606499	APOC1/TREM2/TIMP1/CST3/NUPR1/TSPO/SORL1/FBP1/ZFP36/HMOX1/SLC11A1/TIMP2/HGF/FLNA/CTSA/SDCBP/YBX1/PABPC1/IL10RA/DDIT4/NAMPT/IRAK3/LRRK2/MYD88/MCL1/IL1B/STAT3/ROCK1/TAB2/CAMLG	30
GO:0060191	regulation of lipase activity	12/1068	91/18722	0.00547028127429644	0.0239591215552789	APOC1/PPT1/C5AR1/CD86/RHOA/PTAFR/NR1H3/GNA15/GNA13/LRP1/GNAQ/RGS2	12
GO:1990874	vascular associated smooth muscle cell proliferation	12/1068	91/18722	0.00547028127429644	0.0239591215552789	SOD2/HMOX1/JUN/MEF2C/GNAI2/RHOA/JAK2/NQO2/MMP2/CDKN1A/GNA13/PAK1	12
GO:0072330	monocarboxylic acid biosynthetic process	22/1068	214/18722	0.00549488240873747	0.0240473523743288	APOC1/CD74/FABP5/SDS/LPL/PDK4/ALOX5/TBXAS1/CYP27A1/SCD/OSBPL1A/ABHD2/LPGAT1/PTGS1/NR1H3/LTC4S/PRKAG2/GPX4/IL1B/QKI/HACD4/SCP2	22
GO:0006633	fatty acid biosynthetic process	18/1068	163/18722	0.00551410316243961	0.0240923892020438	APOC1/CD74/FABP5/LPL/PDK4/ALOX5/TBXAS1/SCD/ABHD2/LPGAT1/PTGS1/NR1H3/LTC4S/PRKAG2/GPX4/IL1B/QKI/HACD4	18
GO:0010976	positive regulation of neuron projection development	18/1068	163/18722	0.00551410316243961	0.0240923892020438	APOE/GRN/LYN/HGF/ACTR2/FLNA/TWF2/RAP1A/CAMK1D/SCARB2/PTK2B/CYFIP1/LRP1/SETX/IQGAP1/TMEM30A/RGS2/DBNL	18
GO:0050688	regulation of defense response to virus	10/1068	69/18722	0.00554017644830891	0.0241867250121965	PYCARD/STAT1/FGL2/IFIT1/LILRB1/PARP9/DTX3L/TNFAIP3/HTRA1/PCBP2	10
GO:0071229	cellular response to acid chemical	11/1068	80/18722	0.00558061771144507	0.0243435838083732	CYBA/CYBB/VEGFA/RRAGD/KLF2/MMP2/LAMTOR4/CEBPB/SESN3/LAMTOR2/PLEC	11
GO:0030502	negative regulation of bone mineralization	5/1068	21/18722	0.00565753202213093	0.0244841875010273	CCL3/SRGN/HIF1A/CCR1/PTK2B	5
GO:0033630	positive regulation of cell adhesion mediated by integrin	5/1068	21/18722	0.00565753202213093	0.0244841875010273	NCKAP1L/SYK/CIB1/PTPN6/ADAM9	5
GO:0044766	multi-organism transport	5/1068	21/18722	0.00565753202213093	0.0244841875010273	BST2/IFIT1/SIGLEC1/KPNA3/RAB7A	5
GO:0046514	ceramide catabolic process	5/1068	21/18722	0.00565753202213093	0.0244841875010273	ASAH1/GALC/HEXA/ACER3/GM2A	5
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	5/1068	21/18722	0.00565753202213093	0.0244841875010273	CD74/LAPTM5/CD36/LILRB1/TLR4	5
GO:0071498	cellular response to fluid shear stress	5/1068	21/18722	0.00565753202213093	0.0244841875010273	MEF2C/KLF4/KLF2/PTK2B/PLEC	5
GO:0150105	protein localization to cell-cell junction	5/1068	21/18722	0.00565753202213093	0.0244841875010273	ACTB/PECAM1/FLNA/JAK1/PAK2	5
GO:1902307	positive regulation of sodium ion transmembrane transport	5/1068	21/18722	0.00565753202213093	0.0244841875010273	ATP1B1/GLRX/WNK1/KIF5B/ATP1B3	5
GO:1902579	multi-organism localization	5/1068	21/18722	0.00565753202213093	0.0244841875010273	BST2/IFIT1/SIGLEC1/KPNA3/RAB7A	5
GO:0043534	blood vessel endothelial cell migration	19/1068	176/18722	0.0056582249469572	0.0244841875010273	APOE/TMSB4X/GPX1/HMOX1/HIF1A/MEF2C/RHOA/CIB1/KLF4/VEGFA/TGFB1/VASH1/STAT5A/SPRED1/PTK2B/PRCP/RGCC/ADAM17/NR4A1	19
GO:0090277	positive regulation of peptide hormone secretion	13/1068	103/18722	0.00571493144099782	0.0247097516471348	HLA-DRB1/GLUL/HIF1A/JAK2/TRPM2/RAB8B/SERP1/RAC1/ABCG1/LRP1/STX4/ACSL4/KIF5B	13
GO:0030278	regulation of ossification	14/1068	115/18722	0.0058325138419217	0.0251576696171139	CCL3/SRGN/ISG15/SLC8A1/BMP2K/HIF1A/MEF2C/PTGER4/ALOX5/P2RX7/CCR1/TGFB1/PTK2B/DHRS3	14
GO:0046916	cellular transition metal ion homeostasis	14/1068	115/18722	0.0058325138419217	0.0251576696171139	FTL/FTH1/HAMP/HMOX1/SLC11A1/HIF1A/ATP6V0D1/PRNP/ATP6V1A/MT1X/SLC31A1/SCO2/SLC30A1/ATP6AP1	14
GO:0051209	release of sequestered calcium ion into cytosol	14/1068	115/18722	0.0058325138419217	0.0251576696171139	CYBA/CCL3/SLC8A1/PTPRC/LYN/CORO1A/PTPN6/TRPM2/PTK2B/MCOLN1/ERO1A/CALM3/GSTO1/BAX	14
GO:0030042	actin filament depolymerization	9/1068	59/18722	0.00592264793715749	0.0254650265090851	CAPG/PLEK/TWF2/CAPZA2/CAPZA1/GSN/FLII/CFL1/CAPZB	9
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	9/1068	59/18722	0.00592264793715749	0.0254650265090851	LYN/KLF4/TGFB1/FGR/PTK2B/SOCS3/CDC42/PIK3R1/SOCS6	9
GO:0046324	regulation of glucose import	9/1068	59/18722	0.00592264793715749	0.0254650265090851	MEF2A/PEA15/RHOQ/RAP1A/CREBL2/PRKAG2/OSBPL8/APPL1/PIK3R1	9
GO:0048010	vascular endothelial growth factor receptor signaling pathway	9/1068	59/18722	0.00592264793715749	0.0254650265090851	HIF1A/AXL/VEGFA/ITGA5/MAPKAPK3/PTK2B/IL1B/VEGFB/PAK2	9
GO:0046326	positive regulation of glucose import	7/1068	39/18722	0.00595737226910529	0.0255939337293727	MEF2A/RHOQ/RAP1A/CREBL2/OSBPL8/APPL1/PIK3R1	7
GO:0008643	carbohydrate transport	17/1068	152/18722	0.0060592738662801	0.0259903352801649	FABP5/C3/MEF2A/PEA15/RHOQ/RAP1A/AQP9/CREBL2/SLC37A2/PRKAG2/OSBPL8/SLC2A3/TMEM144/MFSD12/IL1B/APPL1/PIK3R1	17
GO:0098754	detoxification	17/1068	152/18722	0.0060592738662801	0.0259903352801649	APOE/GPX1/SOD2/ALOX5AP/CD36/ALDH1A1/MGST1/PTGS1/MT1X/GLRX/LTC4S/RDH11/GPX4/MGST2/SLC30A1/AKR1A1/GSTO1	17
GO:0006953	acute-phase response	8/1068	49/18722	0.00611530959885292	0.0261475519773458	HAMP/SERPINA1/CD163/PLSCR1/IL6R/IL1B/STAT3/CEBPB	8
GO:0014075	response to amine	8/1068	49/18722	0.00611530959885292	0.0261475519773458	RGS10/HNMT/NR4A2/HPRT1/CALM3/NR4A1/RGS2/RANBP2	8
GO:0034332	adherens junction organization	8/1068	49/18722	0.00611530959885292	0.0261475519773458	ACTB/VEGFA/CSK/NUMB/PAK2/ADAM10/CDC42/PLEC	8
GO:0070741	response to interleukin-6	8/1068	49/18722	0.00611530959885292	0.0261475519773458	HAMP/SPI1/JAK1/JAK2/SELPLG/IL6R/STAT3/CEBPA	8
GO:0006096	glycolytic process	11/1068	81/18722	0.00613354725799702	0.02620476722419	NUPR1/FBP1/HIF1A/P2RX7/DDIT4/PRKAG2/ADPGK/STAT3/LDHA/PGK1/PKM	11
GO:0034368	protein-lipid complex remodeling	6/1068	30/18722	0.00619738184617157	0.0263741985251334	APOE/APOC1/PLA2G7/LPL/PLTP/ABCG1	6
GO:0034369	plasma lipoprotein particle remodeling	6/1068	30/18722	0.00619738184617157	0.0263741985251334	APOE/APOC1/PLA2G7/LPL/PLTP/ABCG1	6
GO:0051125	regulation of actin nucleation	6/1068	30/18722	0.00619738184617157	0.0263741985251334	GMFG/CORO1A/WAS/CYFIP1/GSN/BRK1	6
GO:0051491	positive regulation of filopodium assembly	6/1068	30/18722	0.00619738184617157	0.0263741985251334	RHOQ/ARAP1/RALA/TGFBR1/CDC42/PIK3R1	6
GO:0015748	organophosphate ester transport	16/1068	140/18722	0.00620253112090333	0.0263741985251334	APOE/APOC1/NPC2/PLSCR1/PLTP/SLC25A24/P2RX7/SLC25A19/LRRC8C/SLC37A2/SCARB2/OSBPL8/ABCG1/ABCA1/TMEM30A/SCP2	16
GO:0031333	negative regulation of protein-containing complex assembly	16/1068	140/18722	0.00620253112090333	0.0263741985251334	TMSB4X/CAPG/TREM2/SORL1/TMSB10/TWF2/PTGER4/EIF4EBP1/MYADM/CAPZA2/CAPZA1/GSN/FLII/CDC42/CAPZB/PFN1	16
GO:0034976	response to endoplasmic reticulum stress	25/1068	256/18722	0.00622870527767793	0.0264646406916143	NUPR1/JUN/TMBIM6/HSPA1A/ALOX5/BID/NR1H3/LRRK2/SERP1/EIF2AK2/GRINA/MAN1A1/CEBPB/ERO1A/HM13/TMCO1/PPP1R15A/CANX/DNAJC3/HERPUD1/BAX/ATF3/FLOT1/PIK3R1/SDF2L1	25
GO:0048732	gland development	38/1068	436/18722	0.00628667295394359	0.0266618587966348	PSAP/GPX1/MAFB/HAMP/TSPO/HMOX1/ID2/CSF1R/MSN/HIF1A/HGF/UCP2/USF2/OAS2/RAP1A/VEGFA/PLXND1/TGFB1/TGFBR2/CRIP1/JAK2/NCOR2/NOTCH2/RPS6KA1/STAT5A/STAT6/TNFAIP3/ACAT1/CPT1A/CEBPB/IGF2R/TGFBR1/RTN4/CEBPA/ARF6/CDC42/UBE3A/BAX	38
GO:0006639	acylglycerol metabolic process	15/1068	128/18722	0.00628765041960737	0.0266618587966348	APOE/APOC1/GPX1/C3/SORL1/LPL/ABHD2/LPGAT1/NR1H3/APOBR/ACSL1/ABHD12/CPT1A/PLA2G15/ACSL4	15
GO:0008286	insulin receptor signaling pathway	14/1068	116/18722	0.00629488660246716	0.0266618587966348	SORL1/GRB2/GNAI2/PDK4/RHOQ/OSBPL8/SOCS3/IL1B/SESN3/APC/PAK1/APPL1/PIK3R1/ZNF106	14
GO:0051283	negative regulation of sequestering of calcium ion	14/1068	116/18722	0.00629488660246716	0.0266618587966348	CYBA/CCL3/SLC8A1/PTPRC/LYN/CORO1A/PTPN6/TRPM2/PTK2B/MCOLN1/ERO1A/CALM3/GSTO1/BAX	14
GO:0009266	response to temperature stimulus	19/1068	178/18722	0.00637963874818747	0.0269996319099761	CXCR4/SOD2/CD14/FOS/HMOX1/TFEC/ARRB2/LYN/UCP2/LPL/METRNL/HSPA1A/IRAK1/TRPM2/CDKN1A/NFKBIA/ERO1A/ATM/DNAJC3	19
GO:0015850	organic hydroxy compound transport	27/1068	284/18722	0.00655095632393775	0.0277029469623574	APOE/APOC1/SPP1/MSR1/NPC2/TREM2/TSPO/ACTB/CD36/SLCO2B1/SOAT1/SLC16A3/SYK/PLTP/LILRB1/AQP9/OSBPL1A/ABCC3/NR1H3/OSBPL8/ABCG1/LRP1/NFKBIA/ABCA1/STX12/ARL8B/SCP2	27
GO:0002712	regulation of B cell mediated immunity	9/1068	60/18722	0.00662393017559282	0.0277681715297704	TREM2/C3/HLA-E/PTPRC/TGFB1/PTPN6/BTK/BCL6/STAT6	9
GO:0002889	regulation of immunoglobulin mediated immune response	9/1068	60/18722	0.00662393017559282	0.0277681715297704	TREM2/C3/HLA-E/PTPRC/TGFB1/PTPN6/BTK/BCL6/STAT6	9
GO:0009620	response to fungus	9/1068	60/18722	0.00662393017559282	0.0277681715297704	HAMP/COTL1/SPI1/CLEC7A/SYK/TLR4/SCIMP/BTK/MYD88	9
GO:0061951	establishment of protein localization to plasma membrane	9/1068	60/18722	0.00662393017559282	0.0277681715297704	VAMP5/GGA2/CSK/ATP2C1/GGA1/RILPL2/RAB10/RAB8A/RAB7A	9
GO:0048284	organelle fusion	16/1068	141/18722	0.0066371323311222	0.0277681715297704	CORO1A/VAT1/SAMD9/STX10/STX6/RAB8B/STX4/STX12/ARL8B/BAX/STX7/CHMP3/RAB8A/KIF5B/RAB7A/RAB13	16
GO:0050678	regulation of epithelial cell proliferation	34/1068	381/18722	0.00664733432831027	0.0277681715297704	APOE/B2M/GPX1/CYBA/GRN/GLUL/NUPR1/C5AR1/STAT1/ZFP36/HMOX1/HIF1A/MEF2C/ZFP36L1/RB1/ALOX5/VEGFA/TNFSF12/TGFB1/VASH1/NOTCH2/STAT5A/ITGA4/STAT3/TNFAIP3/RGCC/VEGFB/HTRA1/TGFBR1/RTN4/ADAM17/NR4A1/CDC42/BAX	34
GO:0002517	T cell tolerance induction	4/1068	14/18722	0.00664871712684644	0.0277681715297704	HLA-B/LILRB4/TGFBR2/LILRB2	4
GO:0032688	negative regulation of interferon-beta production	4/1068	14/18722	0.00664871712684644	0.0277681715297704	PYCARD/REL/SIRPA/LILRB1	4
GO:0034616	response to laminar fluid shear stress	4/1068	14/18722	0.00664871712684644	0.0277681715297704	KLF4/KLF2/ADAM9/ABCA1	4
GO:0043374	CD8-positive, alpha-beta T cell differentiation	4/1068	14/18722	0.00664871712684644	0.0277681715297704	LILRB4/NCKAP1L/RUNX1/IRF1	4
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	4/1068	14/18722	0.00664871712684644	0.0277681715297704	SPRED1/ATM/DDX5/ZNF385A	4
GO:0045820	negative regulation of glycolytic process	4/1068	14/18722	0.00664871712684644	0.0277681715297704	NUPR1/FBP1/DDIT4/STAT3	4
GO:0051764	actin crosslink formation	4/1068	14/18722	0.00664871712684644	0.0277681715297704	MARCKS/AIF1/LCP1/FLNA	4
GO:0070278	extracellular matrix constituent secretion	4/1068	14/18722	0.00664871712684644	0.0277681715297704	TNFRSF1B/ENG/RGCC/TNFRSF1A	4
GO:0090715	immunological memory formation process	4/1068	14/18722	0.00664871712684644	0.0277681715297704	HLA-DRA/HLA-DRB1/FGL2/BCL6	4
GO:0097531	mast cell migration	4/1068	14/18722	0.00664871712684644	0.0277681715297704	VEGFA/RIN3/RAC1/VEGFB	4
GO:0001892	embryonic placenta development	11/1068	82/18722	0.00672858558021133	0.0280366392207107	GRB2/JUNB/HIF1A/ZFP36L1/ST14/VASH1/PRDM1/STK4/SOCS3/CEBPB/CEBPA	11
GO:0006757	ATP generation from ADP	11/1068	82/18722	0.00672858558021133	0.0280366392207107	NUPR1/FBP1/HIF1A/P2RX7/DDIT4/PRKAG2/ADPGK/STAT3/LDHA/PGK1/PKM	11
GO:1905897	regulation of response to endoplasmic reticulum stress	11/1068	82/18722	0.00672858558021133	0.0280366392207107	NUPR1/TMBIM6/HSPA1A/ALOX5/NR1H3/LRRK2/GRINA/PPP1R15A/HERPUD1/BAX/PIK3R1	11
GO:0006638	neutral lipid metabolic process	15/1068	129/18722	0.00675091184010372	0.0281079631861109	APOE/APOC1/GPX1/C3/SORL1/LPL/ABHD2/LPGAT1/NR1H3/APOBR/ACSL1/ABHD12/CPT1A/PLA2G15/ACSL4	15
GO:1903828	negative regulation of cellular protein localization	14/1068	117/18722	0.00678611854476728	0.0282327645856316	SPI1/LILRB4/CD36/GBP1/RHOQ/SP100/TGFB1/MDFIC/ABI3/CSK/LRRK2/NUMB/PICALM/ARF6	14
GO:0050803	regulation of synapse structure or activity	22/1068	218/18722	0.00680864154571527	0.0283046454396607	APOE/TREM2/SRGN/PPT1/MEF2C/ACTR2/TUBA1A/RHOA/TLR2/IL10RA/PRNP/ABI3/LILRB2/TANC2/LRRK2/CYFIP1/CFL1/ADAM10/ARF6/CDC42/UBE3A/DBNL	22
GO:0002714	positive regulation of B cell mediated immunity	7/1068	40/18722	0.00687327980837767	0.028485574382493	TREM2/C3/HLA-E/PTPRC/TGFB1/BTK/STAT6	7
GO:0002891	positive regulation of immunoglobulin mediated immune response	7/1068	40/18722	0.00687327980837767	0.028485574382493	TREM2/C3/HLA-E/PTPRC/TGFB1/BTK/STAT6	7
GO:0071276	cellular response to cadmium ion	7/1068	40/18722	0.00687327980837767	0.028485574382493	FOS/HMOX1/CYBB/JUN/NCF1/MT1X/UBE2D3	7
GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	7/1068	40/18722	0.00687327980837767	0.028485574382493	ITGB2/RHOA/ALOX5/KLF4/PTAFR/IRAK1/ITGA4	7
GO:0019083	viral transcription	8/1068	50/18722	0.0069247714547578	0.0286769507059655	CCL3/ZFP36/IFITM3/JUN/USF2/CCL4/MDFIC/TRIM14	8
GO:0032069	regulation of nuclease activity	5/1068	22/18722	0.00698323404324755	0.028874736319819	TMBIM6/OAS1/HSPA1A/OAS2/OAS3	5
GO:0061042	vascular wound healing	5/1068	22/18722	0.00698323404324755	0.028874736319819	CXCR4/ALOX5/VEGFA/HPSE/TNFAIP3	5
GO:0031960	response to corticosteroid	18/1068	167/18722	0.00706853163515756	0.0292050510745101	CYBA/AIF1/ZFP36L2/FOS/DUSP1/ZFP36/CYBB/ZFP36L1/HNMT/RHOA/DDIT4/ENG/PTAFR/CDKN1A/ADAM9/FOSB/CALM3/NR3C1	18
GO:0006753	nucleoside phosphate metabolic process	42/1068	497/18722	0.0071520755913723	0.0295276204216105	TMSB4X/TYMP/TREM2/NUPR1/FBP1/SAMHD1/PPT1/HIF1A/UPP1/PDK4/RHOA/NUDT3/DPYD/RHOQ/P2RX7/PARP9/KYNU/TGFB1/DDIT4/ATP6V1A/NAMPT/ENTPD1/ACOT9/LRRK2/IMPDH1/PRKAG2/ACSL1/LACC1/ADPGK/RNASEH2B/PAPSS1/HPRT1/STAT3/MBD4/ACAT1/LDHA/ADCY7/TK2/PGK1/PKM/ACSL4/HSD17B4	42
GO:0007565	female pregnancy	20/1068	193/18722	0.00722122356450981	0.0297903076101643	SPP1/CTSB/TIMP1/FOS/HAVCR2/ARHGDIB/LGALS9/JUNB/VMP1/UCP2/VEGFA/TGFBR2/PRDM1/NAMPT/MMP2/IL1B/ADCY7/FOSB/ACSL4/RGS2	20
GO:0002793	positive regulation of peptide secretion	13/1068	106/18722	0.0072677588238423	0.029959378619903	HLA-DRB1/GLUL/HIF1A/JAK2/TRPM2/RAB8B/SERP1/RAC1/ABCG1/LRP1/STX4/ACSL4/KIF5B	13
GO:0022612	gland morphogenesis	14/1068	118/18722	0.00730744685956024	0.030031213445687	CSF1R/MSN/HGF/PLXND1/TGFB1/TGFBR2/CRIP1/NOTCH2/RPS6KA1/STAT6/TNFAIP3/CEBPB/CDC42/BAX	14
GO:0034219	carbohydrate transmembrane transport	14/1068	118/18722	0.00730744685956024	0.030031213445687	FABP5/C3/MEF2A/PEA15/RHOQ/RAP1A/CREBL2/PRKAG2/OSBPL8/SLC2A3/TMEM144/IL1B/APPL1/PIK3R1	14
GO:0051101	regulation of DNA binding	14/1068	118/18722	0.00730744685956024	0.030031213445687	TMSB4X/PLAUR/IFI16/HMOX1/JUN/RB1/KLF4/SP100/TGFB1/JAK2/NFKBIA/SUMO3/CALM3/SKI	14
GO:0051282	regulation of sequestering of calcium ion	14/1068	118/18722	0.00730744685956024	0.030031213445687	CYBA/CCL3/SLC8A1/PTPRC/LYN/CORO1A/PTPN6/TRPM2/PTK2B/MCOLN1/ERO1A/CALM3/GSTO1/BAX	14
GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	6/1068	31/18722	0.0073212569970395	0.0300650705905823	GPX1/HMOX1/HGF/PEA15/ARHGEF2/TNFAIP3	6
GO:0030330	DNA damage response, signal transduction by p53 class mediator	10/1068	72/18722	0.00749572783020871	0.0307581348835028	CD74/CD44/SP100/PLK3/SPRED1/CDKN1A/RPS27L/ATM/DDX5/ZNF385A	10
GO:0099173	postsynapse organization	18/1068	168/18722	0.00750795682430287	0.0307615300105834	APOE/TREM2/SRGN/LGMN/ACTB/ACTR2/DOCK10/PRNP/ABI3/LILRB2/TANC2/LRRK2/CFL1/ADAM10/ARF6/CDC42/UBE3A/DBNL	18
GO:1902806	regulation of cell cycle G1/S phase transition	18/1068	168/18722	0.00750795682430287	0.0307615300105834	GPNMB/AIF1/ID2/RB1/KLF4/BID/PTPN6/PLK3/SLFN11/CDKN1A/KMT2E/RPS27L/RGCC/ATM/ADAM17/APC/PSME2/APPL1	18
GO:0008361	regulation of cell size	19/1068	181/18722	0.0076007955463805	0.0311182797938309	APOE/SPP1/PLEK/MSN/DPYSL2/RHOA/TMEM123/TWF2/P2RX7/VEGFA/ARHGAP4/CYFIP1/RAC1/SHTN1/LRP1/LAMTOR4/RTN4/PAK1/DBNL	19
GO:0042886	amide transport	28/1068	301/18722	0.00760876672092998	0.0311272973662913	HLA-DRB1/CD74/PSAP/GLUL/HIF1A/SLC15A3/UCP2/PLTP/MGST1/ALOX5/TAPBP/TAP1/AQP9/TCIRG1/JAK2/CYB5R4/TRPM2/RAB8B/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/ABCA1/STX4/ACSL4/KIF5B	28
GO:0009259	ribonucleotide metabolic process	34/1068	385/18722	0.0077529332847617	0.0316715696418211	TMSB4X/TREM2/NUPR1/FBP1/PPT1/HIF1A/UPP1/PDK4/RHOA/NUDT3/DPYD/RHOQ/P2RX7/KYNU/TGFB1/DDIT4/ATP6V1A/ACOT9/LRRK2/IMPDH1/PRKAG2/ACSL1/ADPGK/RNASEH2B/PAPSS1/HPRT1/STAT3/ACAT1/LDHA/ADCY7/PGK1/PKM/ACSL4/HSD17B4	34
GO:0046683	response to organophosphorus	15/1068	131/18722	0.00775941717318152	0.0316715696418211	FOS/DUSP1/STAT1/SLC8A1/JUN/ZFP36L1/AHR/RAP1A/CASP1/P2RX7/AQP9/PTAFR/PTK2B/LDHA/FOSB	15
GO:0050853	B cell receptor signaling pathway	15/1068	131/18722	0.00775941717318152	0.0316715696418211	CD81/MEF2C/NCKAP1L/PTPRC/LYN/MNDA/SYK/CMTM3/LAT2/CD300A/PTPN6/BTK/LPXN/KLHL6/BAX	15
GO:0010874	regulation of cholesterol efflux	8/1068	51/18722	0.0078125727519493	0.0317923397960169	APOE/TREM2/PLTP/NR1H3/ABCG1/LRP1/NFKBIA/ABCA1	8
GO:0032964	collagen biosynthetic process	8/1068	51/18722	0.0078125727519493	0.0317923397960169	VIM/ARRB2/RAP1A/CIITA/TGFB1/ENG/RUNX1/RGCC	8
GO:0071622	regulation of granulocyte chemotaxis	8/1068	51/18722	0.0078125727519493	0.0317923397960169	CD74/C5AR1/CSF1R/C3AR1/NCKAP1L/CAMK1D/RAC1/BST1	8
GO:1903307	positive regulation of regulated secretory pathway	8/1068	51/18722	0.0078125727519493	0.0317923397960169	ITGB2/HLA-F/SYK/PTAFR/ITGAM/FGR/STX4/LAMP1	8
GO:0051693	actin filament capping	7/1068	41/18722	0.00788962185196277	0.032057529753909	CAPG/TWF2/CAPZA2/CAPZA1/GSN/FLII/CAPZB	7
GO:0071470	cellular response to osmotic stress	7/1068	41/18722	0.00788962185196277	0.032057529753909	TSPO/ZFP36L1/LRRC8C/RCSD1/ARHGEF2/CAB39/MICU1	7
GO:0098586	cellular response to virus	11/1068	84/18722	0.00805344489058958	0.0326739764132491	LGALS9/HIF1A/TLR7/OAS1/POU2F2/IRF7/OAS3/IFIH1/RNF135/ADAR/BAX	11
GO:1900542	regulation of purine nucleotide metabolic process	11/1068	84/18722	0.00805344489058958	0.0326739764132491	TMSB4X/TREM2/NUPR1/FBP1/HIF1A/PDK4/P2RX7/DDIT4/PRKAG2/LACC1/STAT3	11
GO:0043270	positive regulation of ion transport	26/1068	275/18722	0.00806934868140815	0.032713903444687	TMSB4X/TREM2/CTSS/CCL3/TSPO/LGALS3/IFNGR2/ARRB2/VMP1/FLNA/CCL4/P2RX7/CCR1/PTAFR/KCNE3/ATP1B1/LILRA2/GLRX/IL1B/CEBPB/CALM3/GSTO1/BAX/WNK1/KIF5B/ATP1B3	26
GO:0048488	synaptic vesicle endocytosis	9/1068	62/18722	0.00821579474340018	0.0332576357354744	ACTB/LRRK2/ITSN2/CALM3/ROCK1/CANX/FCHO2/PICALM/ARF6	9
GO:0140238	presynaptic endocytosis	9/1068	62/18722	0.00821579474340018	0.0332576357354744	ACTB/LRRK2/ITSN2/CALM3/ROCK1/CANX/FCHO2/PICALM/ARF6	9
GO:0032456	endocytic recycling	10/1068	73/18722	0.00825377715807364	0.0333863429872304	SORL1/EHD4/STX6/DENND1B/ACAP2/ARF6/ARL4C/RAB8A/RAB7A/RAB13	10
GO:0031330	negative regulation of cellular catabolic process	25/1068	262/18722	0.00828265996959585	0.033478077300329	APOC1/TREM2/TIMP1/CST3/NUPR1/TSPO/SORL1/ZFP36/HMOX1/SLC11A1/TIMP2/HGF/CTSA/SDCBP/YBX1/PABPC1/IL10RA/NAMPT/LRRK2/MYD88/MCL1/STAT3/ROCK1/TAB2/CAMLG	25
GO:0007569	cell aging	15/1068	132/18722	0.00830684258460214	0.0335506905587673	B2M/LIMS1/SPI1/ID2/YBX1/ZMIZ1/ABI3/VASH1/NAMPT/BCL6/CDKN1A/ERCC1/ATM/NUP62/MORC3	15
GO:0015914	phospholipid transport	12/1068	96/18722	0.00836119618298389	0.0337449623061938	APOE/APOC1/NPC2/PLSCR1/PLTP/P2RX7/SCARB2/OSBPL8/ABCG1/ABCA1/TMEM30A/SCP2	12
GO:0002363	alpha-beta T cell lineage commitment	5/1068	23/18722	0.0085114305495504	0.0342233079324694	RHOA/IL6R/SPN/STAT6/STAT3	5
GO:0006929	substrate-dependent cell migration	5/1068	23/18722	0.0085114305495504	0.0342233079324694	PTPRC/SDCBP/ADAM8/STK4/SHTN1	5
GO:0035162	embryonic hemopoiesis	5/1068	23/18722	0.0085114305495504	0.0342233079324694	HIF1A/VEGFA/TGFBR2/SH2B3/STK4	5
GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	5/1068	23/18722	0.0085114305495504	0.0342233079324694	TYROBP/TREM2/CD53/ADAM9/FLOT1	5
GO:1902410	mitotic cytokinetic process	5/1068	23/18722	0.0085114305495504	0.0342233079324694	RHOA/KLHDC8B/NUP62/CHMP3/CHMP1B	5
GO:0034367	protein-containing complex remodeling	6/1068	32/18722	0.00858512452290382	0.0343698343526451	APOE/APOC1/PLA2G7/LPL/PLTP/ABCG1	6
GO:1900745	positive regulation of p38MAPK cascade	6/1068	32/18722	0.00858512452290382	0.0343698343526451	SPI1/GADD45B/VEGFA/NCF1/IL1B/PJA2	6
GO:1901185	negative regulation of ERBB signaling pathway	6/1068	32/18722	0.00858512452290382	0.0343698343526451	LGMN/PTPN18/PTPRJ/DUSP3/NUP62/RAB7A	6
GO:1901889	negative regulation of cell junction assembly	6/1068	32/18722	0.00858512452290382	0.0343698343526451	CORO1C/TLR2/IL1B/LRP1/ROCK1/RCC2	6
GO:0002679	respiratory burst involved in defense response	4/1068	15/18722	0.00866252311334272	0.0343698343526451	TREM2/GRN/HCK/NCF1	4
GO:0002730	regulation of dendritic cell cytokine production	4/1068	15/18722	0.00866252311334272	0.0343698343526451	BST2/CLEC7A/TLR4/SCIMP	4
GO:0010889	regulation of sequestering of triglyceride	4/1068	15/18722	0.00866252311334272	0.0343698343526451	TREM2/PLIN2/LPL/OSBPL8	4
GO:0023035	CD40 signaling pathway	4/1068	15/18722	0.00866252311334272	0.0343698343526451	TREM2/CD86/ITGA5/TNFAIP3	4
GO:0032486	Rap protein signal transduction	4/1068	15/18722	0.00866252311334272	0.0343698343526451	RAP2B/TIMP2/RAP1A/RAP2A	4
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	4/1068	15/18722	0.00866252311334272	0.0343698343526451	IL18/SYK/LILRA2/IL1B	4
GO:0036376	sodium ion export across plasma membrane	4/1068	15/18722	0.00866252311334272	0.0343698343526451	SLC8A1/ATP1B1/ATP1B3/ATP1A1	4
GO:0042159	lipoprotein catabolic process	4/1068	15/18722	0.00866252311334272	0.0343698343526451	APOE/CTSD/PPT1/ABHD12	4
GO:0042976	activation of Janus kinase activity	4/1068	15/18722	0.00866252311334272	0.0343698343526451	CD300A/JAK2/IL6R/PTK2B	4
GO:0045346	regulation of MHC class II biosynthetic process	4/1068	15/18722	0.00866252311334272	0.0343698343526451	SPI1/TLR4/CIITA/JAK2	4
GO:0046007	negative regulation of activated T cell proliferation	4/1068	15/18722	0.00866252311334272	0.0343698343526451	LGALS9/LILRB4/PRNP/PRKAR1A	4
GO:0051127	positive regulation of actin nucleation	4/1068	15/18722	0.00866252311334272	0.0343698343526451	WAS/CYFIP1/GSN/BRK1	4
GO:0140374	antiviral innate immune response	4/1068	15/18722	0.00866252311334272	0.0343698343526451	MX1/OAS1/IFIT1/RNF135	4
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	4/1068	15/18722	0.00866252311334272	0.0343698343526451	ZFP36L2/ZFP36/ZFP36L1/PABPC1	4
GO:0010718	positive regulation of epithelial to mesenchymal transition	8/1068	52/18722	0.00878319381826845	0.0347637033479006	SDCBP/GLIPR2/TGFB1/ENG/TGFBR2/IL1B/RGCC/TGFBR1	8
GO:0043392	negative regulation of DNA binding	8/1068	52/18722	0.00878319381826845	0.0347637033479006	TMSB4X/IFI16/HMOX1/JUN/SP100/JAK2/NFKBIA/SUMO3	8
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	11/1068	85/18722	0.00878756326288667	0.0347637033479006	CSF1R/IL18/LYN/PARP9/JAK2/IL6R/SH2B3/PARP14/SOCS3/TNFRSF1A/HCLS1	11
GO:0055072	iron ion homeostasis	11/1068	85/18722	0.00878756326288667	0.0347637033479006	FTL/B2M/FTH1/HAMP/HMOX1/SLC11A1/HIF1A/ATP6V0D1/ATP6V1A/ATP6AP1/PICALM	11
GO:0009117	nucleotide metabolic process	41/1068	489/18722	0.00886609630827833	0.0350486854794651	TMSB4X/TYMP/TREM2/NUPR1/FBP1/SAMHD1/PPT1/HIF1A/UPP1/PDK4/RHOA/NUDT3/DPYD/RHOQ/P2RX7/PARP9/KYNU/TGFB1/DDIT4/ATP6V1A/NAMPT/ACOT9/LRRK2/IMPDH1/PRKAG2/ACSL1/LACC1/ADPGK/RNASEH2B/PAPSS1/HPRT1/STAT3/MBD4/ACAT1/LDHA/ADCY7/TK2/PGK1/PKM/ACSL4/HSD17B4	41
GO:0010595	positive regulation of endothelial cell migration	15/1068	133/18722	0.00888452984405958	0.0350701704744298	TMSB4X/GRN/LGMN/HMOX1/HIF1A/CIB1/VEGFA/TGFB1/RIN2/STAT5A/RRAS/PTK2B/RAC1/ADAM17/RHOB	15
GO:0046887	positive regulation of hormone secretion	15/1068	133/18722	0.00888452984405958	0.0350701704744298	SPP1/HLA-DRB1/GLUL/HIF1A/RETN/JAK2/TRPM2/RAB8B/SERP1/RAC1/ABCG1/LRP1/STX4/ACSL4/KIF5B	15
GO:0032691	negative regulation of interleukin-1 beta production	7/1068	42/18722	0.00901257461393901	0.035523632298623	TREM2/ACP5/LILRB4/ARRB2/CARD16/CD33/TNFAIP3	7
GO:0045773	positive regulation of axon extension	7/1068	42/18722	0.00901257461393901	0.035523632298623	TWF2/VEGFA/CYFIP1/SHTN1/LRP1/PAK1/DBNL	7
GO:0043244	regulation of protein-containing complex disassembly	14/1068	121/18722	0.00906466557120185	0.0356693440598631	CAPG/PLEK/TWF2/CIB1/IRAK3/ARHGEF2/CAPZA2/CAPZA1/SETX/APC/GSN/FLII/TAOK1/CAPZB	14
GO:0046323	glucose import	10/1068	74/18722	0.00906937361937217	0.0356693440598631	MEF2A/PEA15/RHOQ/RAP1A/CREBL2/PRKAG2/OSBPL8/SLC2A3/APPL1/PIK3R1	10
GO:0070972	protein localization to endoplasmic reticulum	10/1068	74/18722	0.00906937361937217	0.0356693440598631	SSR3/LRRK2/SPCS3/MAN1A1/TRAM1/RTN4/PPP1R15A/BCAP29/HERPUD1/RAB10	10
GO:0015833	peptide transport	25/1068	264/18722	0.00907946858341527	0.0356830389483676	HLA-DRB1/CD74/GLUL/HIF1A/SLC15A3/UCP2/MGST1/ALOX5/TAPBP/TAP1/TCIRG1/JAK2/CYB5R4/TRPM2/RAB8B/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/ABCA1/STX4/ACSL4/KIF5B	25
GO:0022617	extracellular matrix disassembly	9/1068	63/18722	0.00911316971493947	0.0357633918413188	CTSS/CST3/LCP1/TGFB1/ADAM8/MMP2/LRP1/ADAM10/FLOT1	9
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	9/1068	63/18722	0.00911316971493947	0.0357633918413188	TMBIM6/HSPA1A/LRRK2/GRINA/CEBPB/ERO1A/PPP1R15A/HERPUD1/BAX	9
GO:0043266	regulation of potassium ion transport	13/1068	109/18722	0.00913672749022487	0.0358297830939341	TREM2/CD63/FLNA/PRNP/KCNAB2/KCNE3/ATP1B1/PTK2B/CAB39/KLHL24/WNK1/KIF5B/ATP1B3	13
GO:0032984	protein-containing complex disassembly	22/1068	224/18722	0.00925253908812264	0.0362575896292736	CAPG/PLEK/VMP1/LAMP2/TWF2/CIB1/DDIT4/IRAK3/ARHGEF2/MCOLN1/CAPZA2/CAPZA1/SETX/APC/GSN/FLII/CFL1/TAOK1/CHMP3/KIF5B/CAPZB/CHMP1B	22
GO:0051656	establishment of organelle localization	34/1068	390/18722	0.00934583350805939	0.036596602038816	CD84/HMOX1/LGALS9/HIF1A/LYN/ACTR2/ACTR3/SYK/LAT2/CD300A/MYO5A/TCIRG1/MYO1F/MILR1/BTK/TANC2/ITGA4/MYO1G/ADGRE2/LRRK2/FGR/BLOC1S1/STXBP2/ATP6AP1/BLOC1S2/NUP62/CFL1/TMED10/PICALM/LAMP1/CDC42/KIF5B/KPNB1/CHMP1B	34
GO:0050807	regulation of synapse organization	21/1068	211/18722	0.00938634460899812	0.0367285826759636	APOE/TREM2/SRGN/MEF2C/ACTR2/TUBA1A/RHOA/TLR2/IL10RA/PRNP/ABI3/LILRB2/TANC2/LRRK2/CYFIP1/CFL1/ADAM10/ARF6/CDC42/UBE3A/DBNL	21
GO:0006140	regulation of nucleotide metabolic process	11/1068	86/18722	0.00957237704459232	0.0374022784450544	TMSB4X/TREM2/NUPR1/FBP1/HIF1A/PDK4/P2RX7/DDIT4/PRKAG2/LACC1/STAT3	11
GO:0045921	positive regulation of exocytosis	11/1068	86/18722	0.00957237704459232	0.0374022784450544	ITGB2/HLA-F/SDCBP/SYK/PTAFR/ITGAM/FGR/ATP6AP1/STX4/LAMP1/RAB7A	11
GO:0051208	sequestering of calcium ion	14/1068	122/18722	0.00971911930193132	0.0378754376492768	CYBA/CCL3/SLC8A1/PTPRC/LYN/CORO1A/PTPN6/TRPM2/PTK2B/MCOLN1/ERO1A/CALM3/GSTO1/BAX	14
GO:0051928	positive regulation of calcium ion transport	14/1068	122/18722	0.00971911930193132	0.0378754376492768	CCL3/TSPO/LGALS3/ARRB2/VMP1/CCL4/P2RX7/CCR1/KCNE3/ATP1B1/LILRA2/CALM3/GSTO1/BAX	14
GO:0034284	response to monosaccharide	22/1068	225/18722	0.00972154950782956	0.0378754376492768	HLA-DRB1/LGALS1/CYBA/TREM2/TXNIP/GLUL/SOD2/SLC8A1/HIF1A/UCP2/LPL/RHOA/TGFBR2/NAMPT/PTK2B/RAC1/ABCG1/LRP1/LDHA/STX4/EGR1/KIF5B	22
GO:0050769	positive regulation of neurogenesis	22/1068	225/18722	0.00972154950782956	0.0378754376492768	CXCR4/TSPO/ID2/SKIL/HIF1A/LYN/ACTR2/PLXNC1/TWF2/TLR2/TNFRSF1B/VEGFA/PLXND1/TGFB1/IL1B/CYFIP1/SHTN1/LRP1/NUMB/PAK1/SPEN/DBNL	22
GO:0070301	cellular response to hydrogen peroxide	12/1068	98/18722	0.00980583106548693	0.0381762369620256	HGF/AXL/SIRPA/KLF4/KLF2/TRPM2/LRRK2/STAT6/TNFAIP3/SETX/RHOB/PPIF	12
GO:1904659	glucose transmembrane transport	13/1068	110/18722	0.00983698082004188	0.038230875704907	FABP5/C3/MEF2A/PEA15/RHOQ/RAP1A/CREBL2/PRKAG2/OSBPL8/SLC2A3/IL1B/APPL1/PIK3R1	13
GO:0007566	embryo implantation	8/1068	53/18722	0.00984112052522531	0.038230875704907	SPP1/TIMP1/ARHGDIB/VMP1/VEGFA/TGFBR2/MMP2/IL1B	8
GO:0008347	glial cell migration	8/1068	53/18722	0.00984112052522531	0.038230875704907	TREM2/CD9/CCL3/TSPO/GPR183/ZMIZ1/LRP1/RTN4	8
GO:0034329	cell junction assembly	36/1068	420/18722	0.00984963162834364	0.0382364117025484	CD9/LIMS1/MTDH/ACTB/MEF2C/PECAM1/VMP1/SDCBP/RHOA/CORO1C/TLR2/RAP1A/VEGFA/PLXND1/ABI3/TLN1/PTK2B/RAB29/PTPRJ/CAPZA1/IL1B/RAC1/LRP1/DUSP3/IQGAP1/PAK2/ROCK1/APC/ARF6/CDC42/RCC2/DBNL/FLOT1/PLEC/RAB13/S100A10	36
GO:0036465	synaptic vesicle recycling	10/1068	75/18722	0.00994521865931369	0.0385520114121097	ACTB/LRRK2/ITSN2/CYFIP1/CALM3/ROCK1/CANX/FCHO2/PICALM/ARF6	10
GO:0048662	negative regulation of smooth muscle cell proliferation	10/1068	75/18722	0.00994521865931369	0.0385520114121097	APOE/AIF1/SOD2/HMOX1/MEF2C/RHOA/KLF4/CDKN1A/GNA13/TNFAIP3	10
GO:0060402	calcium ion transport into cytosol	17/1068	160/18722	0.00996466275127899	0.0385996555677684	CYBA/CCL3/SLC8A1/PTPRC/LYN/TMBIM6/CORO1A/P2RX7/PRNP/PTPN6/TRPM2/PTK2B/MCOLN1/ERO1A/CALM3/GSTO1/BAX	17
GO:0070570	regulation of neuron projection regeneration	6/1068	33/18722	0.00999792720183682	0.0387007282504386	SPP1/GRN/HGF/FLNA/KLF4/LRP1	6
GO:0001101	response to acid chemical	15/1068	135/18722	0.0101352128594171	0.0392040204942042	CYBA/CD9/CYBB/LYN/RHOA/TMBIM6/VEGFA/RRAGD/KLF2/MMP2/LAMTOR4/CEBPB/SESN3/LAMTOR2/PLEC	15
GO:0050767	regulation of neurogenesis	32/1068	364/18722	0.0101987664912229	0.039421593113638	SPP1/B2M/TREM2/CXCR4/TSPO/SORL1/YWHAH/ID2/SKIL/HIF1A/LYN/ACTR2/PLXNC1/TWF2/TLR2/TNFRSF1B/VEGFA/PLXND1/TGFB1/ARHGAP4/IL1B/CYFIP1/SHTN1/LRP1/NUMB/RTN4/PAK1/BHLHE40/SKI/SPEN/DBNL/BHLHE41	32
GO:0035458	cellular response to interferon-beta	5/1068	24/18722	0.0102561883397464	0.0394457535860808	IFI16/STAT1/MNDA/OAS1/IRF1	5
GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	5/1068	24/18722	0.0102561883397464	0.0394457535860808	HIF1A/VEGFA/KLF2/CEBPB/ATF3	5
GO:0036010	protein localization to endosome	5/1068	24/18722	0.0102561883397464	0.0394457535860808	SORL1/MSN/DTX3L/TMEM30A/ARF6	5
GO:0045649	regulation of macrophage differentiation	5/1068	24/18722	0.0102561883397464	0.0394457535860808	C1QC/ID2/RB1/TGFB1/HCLS1	5
GO:0050855	regulation of B cell receptor signaling pathway	5/1068	24/18722	0.0102561883397464	0.0394457535860808	CD81/LYN/CMTM3/CD300A/LPXN	5
GO:0060149	negative regulation of posttranscriptional gene silencing	5/1068	24/18722	0.0102561883397464	0.0394457535860808	NEAT1/TGFB1/NCOR2/STAT3/ADAR	5
GO:0060967	negative regulation of gene silencing by RNA	5/1068	24/18722	0.0102561883397464	0.0394457535860808	NEAT1/TGFB1/NCOR2/STAT3/ADAR	5
GO:0014074	response to purine-containing compound	16/1068	148/18722	0.01041066605474	0.0400113632702114	FOS/DUSP1/STAT1/SLC8A1/JUN/ZFP36L1/AHR/RAP1A/CASP1/P2RX7/AQP9/PTAFR/TRPM2/PTK2B/LDHA/FOSB	16
GO:0098657	import into cell	22/1068	227/18722	0.0107171929540385	0.0411601232597806	TREM2/SLC8A1/ACTB/CD36/SLC15A3/IL10RA/PRNP/LRRC8C/TRPM2/SLC6A6/ITGA4/ATP1B1/ACSL1/SLC2A3/SLC31A1/SLC30A1/SLC1A3/RGS2/WNK1/FLOT1/ATP1B3/ATP1A1	22
GO:0003158	endothelium development	15/1068	136/18722	0.0108105004028985	0.041488947492205	GPX1/CXCR4/MSN/PECAM1/RHOA/ITGAX/RAP1A/VEGFA/MYADM/MYD88/IL1B/BTG1/TNFRSF1A/ROCK1/RHOB	15
GO:0140029	exocytic process	10/1068	76/18722	0.0108840266571595	0.0417414412523331	PLEK/LYN/SYK/BTK/RAB8B/STXBP2/STX4/RAB10/RAB8A/RAB13	10
GO:0000082	G1/S transition of mitotic cell cycle	21/1068	214/18722	0.0109211937753547	0.0418212973876173	GPNMB/AIF1/ID2/RB1/EIF4EBP1/KLF4/BID/PTPN6/PLK3/SLFN11/CDKN1A/KMT2E/RPS27L/RGCC/ATM/ADAM17/APC/BACH1/PIAS1/PSME2/APPL1	21
GO:0030834	regulation of actin filament depolymerization	8/1068	54/18722	0.0109908277395664	0.0418212973876173	CAPG/PLEK/TWF2/CAPZA2/CAPZA1/GSN/FLII/CAPZB	8
GO:0070839	metal ion export	8/1068	54/18722	0.0109908277395664	0.0418212973876173	SLC8A1/SLC11A1/KCNE3/ATP1B1/ATOX1/CALM3/ATP1B3/ATP1A1	8
GO:0002371	dendritic cell cytokine production	4/1068	16/18722	0.0110366062787189	0.0418212973876173	BST2/CLEC7A/TLR4/SCIMP	4
GO:0002921	negative regulation of humoral immune response	4/1068	16/18722	0.0110366062787189	0.0418212973876173	A2M/PTPN6/VSIG4/SERPING1	4
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	4/1068	16/18722	0.0110366062787189	0.0418212973876173	SP100/CDKN1A/RPS27L/ZNF385A	4
GO:0009299	mRNA transcription	4/1068	16/18722	0.0110366062787189	0.0418212973876173	C5AR1/FLNA/STAT3/DDX5	4
GO:0033631	cell-cell adhesion mediated by integrin	4/1068	16/18722	0.0110366062787189	0.0418212973876173	FERMT3/ITGA4/ADAM9/WNK1	4
GO:0034375	high-density lipoprotein particle remodeling	4/1068	16/18722	0.0110366062787189	0.0418212973876173	APOE/APOC1/PLTP/ABCG1	4
GO:0035751	regulation of lysosomal lumen pH	4/1068	16/18722	0.0110366062787189	0.0418212973876173	GRN/PPT1/ATP6AP2/LRRK2	4
GO:0045651	positive regulation of macrophage differentiation	4/1068	16/18722	0.0110366062787189	0.0418212973876173	ID2/RB1/TGFB1/HCLS1	4
GO:0046135	pyrimidine nucleoside catabolic process	4/1068	16/18722	0.0110366062787189	0.0418212973876173	UPP1/DPYD/APOBEC3C/APOBEC3A	4
GO:0070230	positive regulation of lymphocyte apoptotic process	4/1068	16/18722	0.0110366062787189	0.0418212973876173	LGALS9/ADAM8/FNIP1/BAX	4
GO:0071361	cellular response to ethanol	4/1068	16/18722	0.0110366062787189	0.0418212973876173	SOD2/SPI1/CYBB/ADCY7	4
GO:0099010	modification of postsynaptic structure	4/1068	16/18722	0.0110366062787189	0.0418212973876173	RHOA/CYFIP1/CDC42/PFN1	4
GO:1904683	regulation of metalloendopeptidase activity	4/1068	16/18722	0.0110366062787189	0.0418212973876173	SORL1/MBP/STAT3/PICALM	4
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	4/1068	16/18722	0.0110366062787189	0.0418212973876173	ATP1B1/GLRX/WNK1/KIF5B	4
GO:0050890	cognition	27/1068	296/18722	0.0110602820680546	0.0418816014310333	APOE/HLA-DRA/B2M/TREM2/SGK1/LGMN/FOS/PPT1/C5AR1/JUN/HIF1A/MEF2C/ACTR2/TLR2/PRNP/ATXN1/LILRB2/NQO2/GPR155/BTG2/CYFIP1/CEBPB/PJA2/PICALM/UBE3A/PIAS1/GM2A	27
GO:0003170	heart valve development	9/1068	65/18722	0.0111279125955254	0.0420786379575717	MEF2C/RB1/TNFRSF1B/TGFB1/TGFBR2/PRDM1/NOTCH2/TNFRSF1A/ROCK1	9
GO:0070613	regulation of protein processing	9/1068	65/18722	0.0111279125955254	0.0420786379575717	CTSZ/PRNP/CARD16/RUNX1/ADAM8/LRRK2/PRKACB/GSN/XIAP	9
GO:1903362	regulation of cellular protein catabolic process	24/1068	255/18722	0.0111907083408681	0.0422864581283785	APOE/LAPTM5/GPX1/TREM2/CD81/HAMP/NUPR1/CTSC/MSN/SDCBP/HSPA1A/PLK3/LRRK2/PTK2B/GABARAP/TNFAIP3/LRP1/CEBPA/HERPUD1/UBE3A/PIAS1/PSME2/CAMLG/SUMO2	24
GO:0034250	positive regulation of cellular amide metabolic process	17/1068	162/18722	0.011201234178886	0.0422966127566613	VIM/IFNGR1/RHOA/PABPC1/PTAFR/PTK2B/SERP1/MIF4GD/ABCG1/RPS27L/PPP1R15A/EIF2S3/DNAJC3/PKM/PICALM/UHMK1/CNBP	17
GO:0007260	tyrosine phosphorylation of STAT protein	11/1068	88/18722	0.0113029007033408	0.0426208610728351	CSF1R/IL18/LYN/PARP9/JAK2/IL6R/SH2B3/PARP14/SOCS3/TNFRSF1A/HCLS1	11
GO:0009144	purine nucleoside triphosphate metabolic process	11/1068	88/18722	0.0113029007033408	0.0426208610728351	TMSB4X/TREM2/SAMHD1/RHOA/RHOQ/TGFB1/ATP6V1A/LRRK2/IMPDH1/PRKAG2/STAT3	11
GO:0048608	reproductive structure development	36/1068	424/18722	0.0113150417322898	0.04263684719793	SPP1/CTSB/PSAP/C3/NUPR1/GRB2/JUNB/HIF1A/ZFP36L1/ARRB2/FLNA/RETN/AXL/MGST1/VEGFA/ST14/CRIP1/VASH1/PRDM1/PTPN6/NOTCH2/TNFSF10/STK4/ERCC1/SOCS3/SGPL1/FNDC3A/CEBPB/ARID4A/HTRA1/TGFBR1/CEBPA/UBE3A/BAX/HSD17B4/RAB13	36
GO:0006641	triglyceride metabolic process	12/1068	100/18722	0.0114368518572646	0.0430657729391484	APOE/APOC1/GPX1/C3/SORL1/LPL/LPGAT1/NR1H3/APOBR/ACSL1/CPT1A/ACSL4	12
GO:0030879	mammary gland development	15/1068	137/18722	0.0115206308218727	0.0433207832159061	GPX1/ID2/CSF1R/HIF1A/USF2/OAS2/VEGFA/TGFBR2/JAK2/NCOR2/STAT5A/STAT6/CEBPB/RTN4/BAX	15
GO:0045471	response to ethanol	15/1068	137/18722	0.0115206308218727	0.0433207832159061	HAMP/SOD2/CD14/SPI1/CYBB/ACTR2/RHOA/RGS19/EIF4EBP1/TBXAS1/PTK2B/STAT3/CPT1A/ADCY7/RGS2	15
GO:0035308	negative regulation of protein dephosphorylation	6/1068	34/18722	0.0115683976143622	0.0433794812558014	LGALS3/NCKAP1L/GNAI2/ROCK1/PPP1R15A/BOD1L1	6
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	6/1068	34/18722	0.0115683976143622	0.0433794812558014	CD74/CD44/SPRED1/ATM/DDX5/ZNF385A	6
GO:0048261	negative regulation of receptor-mediated endocytosis	6/1068	34/18722	0.0115683976143622	0.0433794812558014	APOC1/SDCBP/RIN3/RAC1/PICALM/ARF6	6
GO:1990000	amyloid fibril formation	6/1068	34/18722	0.0115683976143622	0.0433794812558014	APOE/B2M/TREM2/CD36/GSN/PFDN5	6
GO:0021762	substantia nigra development	7/1068	44/18722	0.0116027840165533	0.0434238884252357	YWHAH/ACTB/GNB4/RHOA/MBP/CALM3/CDC42	7
GO:0048066	developmental pigmentation	7/1068	44/18722	0.0116027840165533	0.0434238884252357	ZEB2/CD63/RAB32/MEF2C/ATP6AP2/MITF/BAX	7
GO:0019693	ribose phosphate metabolic process	34/1068	396/18722	0.0116043823404725	0.0434238884252357	TMSB4X/TREM2/NUPR1/FBP1/PPT1/HIF1A/UPP1/PDK4/RHOA/NUDT3/DPYD/RHOQ/P2RX7/KYNU/TGFB1/DDIT4/ATP6V1A/ACOT9/LRRK2/IMPDH1/PRKAG2/ACSL1/ADPGK/RNASEH2B/PAPSS1/HPRT1/STAT3/ACAT1/LDHA/ADCY7/PGK1/PKM/ACSL4/HSD17B4	34
GO:0050808	synapse organization	36/1068	426/18722	0.0121122135667653	0.045292795846338	APOE/C1QB/TREM2/C3/C1QA/C1QC/SRGN/LGMN/C5AR1/ACTB/CHCHD10/MEF2C/ACTR2/TUBA1A/FLNA/DOCK10/SDCBP/RHOA/TLR2/IL10RA/PRNP/PLXND1/ABI3/LILRB2/ITGAM/TANC2/LRRK2/RAB29/CYFIP1/CFL1/ADAM10/ARF6/CDC42/UBE3A/DBNL/PFN1	36
GO:0006658	phosphatidylserine metabolic process	5/1068	25/18722	0.012230868217601	0.0455354101047453	PLSCR1/OSBPL8/ABHD12/SERINC1/PLA2G15	5
GO:0032469	endoplasmic reticulum calcium ion homeostasis	5/1068	25/18722	0.012230868217601	0.0455354101047453	TMBIM6/GRINA/TMCO1/HERPUD1/BAX	5
GO:0090330	regulation of platelet aggregation	5/1068	25/18722	0.012230868217601	0.0455354101047453	CD9/LYN/SYK/JAK2/SH2B3	5
GO:1903055	positive regulation of extracellular matrix organization	5/1068	25/18722	0.012230868217601	0.0455354101047453	RB1/TGFB1/COLGALT1/RUNX1/RGCC	5
GO:0000768	syncytium formation by plasma membrane fusion	8/1068	55/18722	0.0122367627677936	0.0455354101047453	TYROBP/TREM2/CD9/CD81/CD53/PLEKHO1/ADAM9/FLOT1	8
GO:0061098	positive regulation of protein tyrosine kinase activity	8/1068	55/18722	0.0122367627677936	0.0455354101047453	FCGR1A/CSF1R/HBEGF/PRNP/NCF1/ABI1/PAK2/ADAM17	8
GO:0140253	cell-cell fusion	8/1068	55/18722	0.0122367627677936	0.0455354101047453	TYROBP/TREM2/CD9/CD81/CD53/PLEKHO1/ADAM9/FLOT1	8
GO:0050918	positive chemotaxis	9/1068	66/18722	0.0122521317174639	0.0455354101047453	GPNMB/CCL3/LGALS3/HGF/CORO1A/VEGFA/PTPRJ/LRP1/VEGFB	9
GO:1900407	regulation of cellular response to oxidative stress	11/1068	89/18722	0.0122530421556876	0.0455354101047453	GPX1/TREM2/SOD2/CD36/HIF1A/HGF/ALOX5/TLR4/TRPM2/LRRK2/MCL1	11
GO:0098869	cellular oxidant detoxification	12/1068	101/18722	0.0123268615283009	0.0457782139068904	APOE/GPX1/SOD2/ALOX5AP/CD36/MGST1/PTGS1/GLRX/LTC4S/GPX4/MGST2/GSTO1	12
GO:0043535	regulation of blood vessel endothelial cell migration	16/1068	151/18722	0.0124738806596552	0.0462923384040575	APOE/TMSB4X/HMOX1/HIF1A/MEF2C/RHOA/CIB1/KLF4/VEGFA/TGFB1/VASH1/STAT5A/SPRED1/PRCP/RGCC/ADAM17	16
GO:1901990	regulation of mitotic cell cycle phase transition	27/1068	299/18722	0.0125131504968745	0.046406158131364	GPNMB/AIF1/ZFP36L2/DUSP1/ID2/ZFP36L1/RB1/TAOK3/KLF4/BID/PTPN6/PLK3/SLFN11/CDKN1A/KMT2E/RNASEH2B/RPS27L/RGCC/ATM/FOXN3/ADAM17/APC/DYNC1LI1/TAOK1/RCC2/PSME2/APPL1	27
GO:0061458	reproductive system development	36/1068	427/18722	0.0125276966644482	0.0464281945064302	SPP1/CTSB/PSAP/C3/NUPR1/GRB2/JUNB/HIF1A/ZFP36L1/ARRB2/FLNA/RETN/AXL/MGST1/VEGFA/ST14/CRIP1/VASH1/PRDM1/PTPN6/NOTCH2/TNFSF10/STK4/ERCC1/SOCS3/SGPL1/FNDC3A/CEBPB/ARID4A/HTRA1/TGFBR1/CEBPA/UBE3A/BAX/HSD17B4/RAB13	36
GO:0031929	TOR signaling	14/1068	126/18722	0.0127157523139528	0.0470927930584005	TREM2/CCDC88A/HIF1A/NCKAP1L/EIF4EBP1/DDIT4/RRAGD/GPR137B/TMEM127/LAMTOR4/SESN3/ATM/LAMTOR2/FNIP1	14
GO:0008645	hexose transmembrane transport	13/1068	114/18722	0.013065513928119	0.048316814651056	FABP5/C3/MEF2A/PEA15/RHOQ/RAP1A/CREBL2/PRKAG2/OSBPL8/SLC2A3/IL1B/APPL1/PIK3R1	13
GO:0051261	protein depolymerization	13/1068	114/18722	0.013065513928119	0.048316814651056	CAPG/PLEK/TWF2/CIB1/ARHGEF2/CAPZA2/CAPZA1/APC/GSN/FLII/CFL1/TAOK1/CAPZB	13
GO:0006110	regulation of glycolytic process	7/1068	45/18722	0.0130820730550765	0.048316814651056	NUPR1/FBP1/HIF1A/P2RX7/DDIT4/PRKAG2/STAT3	7
GO:0030835	negative regulation of actin filament depolymerization	7/1068	45/18722	0.0130820730550765	0.048316814651056	CAPG/TWF2/CAPZA2/CAPZA1/GSN/FLII/CAPZB	7
GO:0002028	regulation of sodium ion transport	11/1068	90/18722	0.0132627330530908	0.0488734272300147	FXYD5/YWHAH/SLC8A1/P2RX7/ATP1B1/GLRX/KLHL24/WNK1/KIF5B/ATP1B3/ATP1A1	11
GO:0046031	ADP metabolic process	11/1068	90/18722	0.0132627330530908	0.0488734272300147	NUPR1/FBP1/HIF1A/P2RX7/DDIT4/PRKAG2/ADPGK/STAT3/LDHA/PGK1/PKM	11
GO:0061097	regulation of protein tyrosine kinase activity	11/1068	90/18722	0.0132627330530908	0.0488734272300147	FCGR1A/CSF1R/LILRB4/RAP2B/PTPRC/HBEGF/PRNP/NCF1/ABI1/PAK2/ADAM17	11
GO:0010522	regulation of calcium ion transport into cytosol	12/1068	102/18722	0.0132690086901356	0.0488734272300147	CYBA/SLC8A1/LYN/TMBIM6/CORO1A/P2RX7/PRNP/PTPN6/PTK2B/CALM3/GSTO1/BAX	12
GO:0050796	regulation of insulin secretion	17/1068	165/18722	0.0132802380119956	0.0488814217685732	HLA-DRB1/GLUL/HIF1A/UCP2/ALOX5/TCIRG1/JAK2/TRPM2/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/STX4/ACSL4/KIF5B	17
GO:0048821	erythrocyte development	6/1068	35/18722	0.0133050048982173	0.0489058626912673	NCKAP1L/KLF2/SH2B3/BCL6/ARID4A/PTBP3	6
GO:0097421	liver regeneration	6/1068	35/18722	0.0133050048982173	0.0489058626912673	HAMP/HMOX1/UCP2/RAP1A/CPT1A/CEBPB	6
GO:0006879	cellular iron ion homeostasis	9/1068	67/18722	0.0134587975369633	0.0493367333624009	FTL/FTH1/HAMP/HMOX1/SLC11A1/HIF1A/ATP6V0D1/ATP6V1A/ATP6AP1	9
GO:0010517	regulation of phospholipase activity	9/1068	67/18722	0.0134587975369633	0.0493367333624009	PPT1/C5AR1/CD86/PTAFR/GNA15/GNA13/LRP1/GNAQ/RGS2	9
GO:0061180	mammary gland epithelium development	9/1068	67/18722	0.0134587975369633	0.0493367333624009	GPX1/ID2/CSF1R/HIF1A/JAK2/STAT6/CEBPB/RTN4/BAX	9
GO:1903317	regulation of protein maturation	9/1068	67/18722	0.0134587975369633	0.0493367333624009	CTSZ/PRNP/CARD16/RUNX1/ADAM8/LRRK2/PRKACB/GSN/XIAP	9
GO:0042063	gliogenesis	27/1068	301/18722	0.0135645539282903	0.049690653765821	VIM/TREM2/CD9/C1QA/CCL3/GRN/CXCR4/TSPO/C5AR1/ID2/LYN/GPR183/IFNGR1/RHOA/TLR2/TNFRSF1B/TLR4/ZMIZ1/TGFB1/CSK/PTK2B/IL1B/STAT3/LRP1/RTN4/SKI/PLEC	27
GO:0002090	regulation of receptor internalization	8/1068	56/18722	0.0135833288919585	0.0496919611532257	CD63/ARRB2/SDCBP/SYK/VEGFA/RIN3/NUMB/FLOT1	8
GO:0043470	regulation of carbohydrate catabolic process	8/1068	56/18722	0.0135833288919585	0.0496919611532257	NUPR1/FBP1/HIF1A/P2RX7/DDIT4/SCARB2/PRKAG2/STAT3	8
GO:0036035	osteoclast development	4/1068	17/18722	0.0137923539337578	0.0501506346540143	TYROBP/LILRB1/NOTCH2/ATP6AP1	4
GO:0042053	regulation of dopamine metabolic process	4/1068	17/18722	0.0137923539337578	0.0501506346540143	ITGB2/NR4A2/ITGAM/HPRT1	4
GO:0042069	regulation of catecholamine metabolic process	4/1068	17/18722	0.0137923539337578	0.0501506346540143	ITGB2/NR4A2/ITGAM/HPRT1	4
GO:0042772	DNA damage response, signal transduction resulting in transcription	4/1068	17/18722	0.0137923539337578	0.0501506346540143	SP100/CDKN1A/RPS27L/ZNF385A	4
GO:0042953	lipoprotein transport	4/1068	17/18722	0.0137923539337578	0.0501506346540143	MSR1/CD36/VMP1/LRP1	4
GO:0072673	lamellipodium morphogenesis	4/1068	17/18722	0.0137923539337578	0.0501506346540143	CD44/PLEKHO1/CORO1C/ABI1	4
GO:0097067	cellular response to thyroid hormone stimulus	4/1068	17/18722	0.0137923539337578	0.0501506346540143	CTSB/CTSS/CTSH/LMO2	4
GO:1901550	regulation of endothelial cell development	4/1068	17/18722	0.0137923539337578	0.0501506346540143	VEGFA/IL1B/TNFRSF1A/ROCK1	4
GO:1903140	regulation of establishment of endothelial barrier	4/1068	17/18722	0.0137923539337578	0.0501506346540143	VEGFA/IL1B/TNFRSF1A/ROCK1	4
GO:0009746	response to hexose	21/1068	219/18722	0.013920788271275	0.0505835511863971	HLA-DRB1/LGALS1/CYBA/TREM2/TXNIP/GLUL/SLC8A1/HIF1A/UCP2/LPL/RHOA/TGFBR2/NAMPT/PTK2B/RAC1/ABCG1/LRP1/LDHA/STX4/EGR1/KIF5B	21
GO:0001936	regulation of endothelial cell proliferation	18/1068	179/18722	0.0139521515562357	0.050663398248619	APOE/CYBA/STAT1/HMOX1/HIF1A/MEF2C/ALOX5/VEGFA/TNFSF12/VASH1/STAT5A/ITGA4/STAT3/RGCC/VEGFB/TGFBR1/ADAM17/NR4A1	18
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	10/1068	79/18722	0.0141054272870302	0.0511511328231285	LIMS1/ACTR2/FLNA/CIB1/PREX1/MYADM/RAC1/CDC42/DBNL/S100A10	10
GO:0050772	positive regulation of axonogenesis	10/1068	79/18722	0.0141054272870302	0.0511511328231285	SKIL/PLXNC1/TWF2/VEGFA/PLXND1/CYFIP1/SHTN1/LRP1/PAK1/DBNL	10
GO:0006706	steroid catabolic process	5/1068	26/18722	0.0144480245837923	0.052288088969915	APOE/SPP1/YWHAH/HSD17B11/CYP27A1	5
GO:0097066	response to thyroid hormone	5/1068	26/18722	0.0144480245837923	0.052288088969915	CTSB/CTSS/CTSH/LMO2/CAB39	5
GO:1905523	positive regulation of macrophage migration	5/1068	26/18722	0.0144480245837923	0.052288088969915	TREM2/CCL3/C5AR1/CSF1R/C3AR1	5
GO:0001935	endothelial cell proliferation	19/1068	193/18722	0.0145026265747928	0.052450518094894	APOE/CYBA/STAT1/HMOX1/HIF1A/MEF2C/ALOX5/VEGFA/TNFSF12/VASH1/STAT5A/ITGA4/PRKX/STAT3/RGCC/VEGFB/TGFBR1/ADAM17/NR4A1	19
GO:0019216	regulation of lipid metabolic process	29/1068	331/18722	0.0145654133907859	0.0526423112234967	APOE/APOC1/CD74/FABP5/PSAP/NPC2/TREM2/C3/CD81/TSPO/ASAH1/SORL1/ID2/LACTB/LYN/PDK4/TGFB1/CREBL2/LPGAT1/NR1H3/FGR/PRKAG2/PTK2B/IL1B/ABCG1/CPT1A/CDC42/EGR1/ATP1A1	29
GO:0044706	multi-multicellular organism process	21/1068	220/18722	0.0145924278372646	0.0527046456558767	SPP1/CTSB/TIMP1/FOS/HAVCR2/ARHGDIB/LGALS9/JUNB/VMP1/UCP2/VEGFA/TGFBR2/PTAFR/PRDM1/NAMPT/MMP2/IL1B/ADCY7/FOSB/ACSL4/RGS2	21
GO:0060976	coronary vasculature development	7/1068	46/18722	0.0146919813155012	0.0530287165073206	VEGFA/PLXND1/PRDM1/SPRED1/CNTRL/VEGFB/TGFBR1	7
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	9/1068	68/18722	0.0147512914363715	0.0532071982557891	CSF1R/IL18/LYN/PARP9/JAK2/IL6R/PARP14/TNFRSF1A/HCLS1	9
GO:0034767	positive regulation of ion transmembrane transport	17/1068	167/18722	0.0148264140182132	0.0534067623780228	TMSB4X/TREM2/CTSS/IFNGR2/VMP1/FLNA/P2RX7/PTAFR/KCNE3/ATP1B1/GLRX/CALM3/GSTO1/BAX/WNK1/KIF5B/ATP1B3	17
GO:1903034	regulation of response to wounding	17/1068	167/18722	0.0148264140182132	0.0534067623780228	APOE/SPP1/CD9/GRN/CXCR4/CLEC7A/CD36/FLNA/ALOX5/HBEGF/KLF4/HPSE/PLAU/SH2B3/SERPING1/TNFAIP3/LRP1	17
GO:0050679	positive regulation of epithelial cell proliferation	20/1068	207/18722	0.014944384511709	0.0537382051774718	CYBA/GRN/GLUL/C5AR1/HMOX1/HIF1A/VEGFA/TNFSF12/NOTCH2/STAT5A/ITGA4/STAT3/TNFAIP3/VEGFB/HTRA1/TGFBR1/RTN4/ADAM17/NR4A1/CDC42	20
GO:0007006	mitochondrial membrane organization	13/1068	116/18722	0.0149582624493259	0.0537382051774718	CHCHD10/HSPA1A/ACAA2/BID/BNIP3L/SLC35F6/STAT3/BLOC1S2/CALM3/ALKBH7/OXA1L/BAX/PPIF	13
GO:0015749	monosaccharide transmembrane transport	13/1068	116/18722	0.0149582624493259	0.0537382051774718	FABP5/C3/MEF2A/PEA15/RHOQ/RAP1A/CREBL2/PRKAG2/OSBPL8/SLC2A3/IL1B/APPL1/PIK3R1	13
GO:0021782	glial cell development	13/1068	116/18722	0.0149582624493259	0.0537382051774718	VIM/TREM2/CD9/C1QA/GRN/C5AR1/LYN/IFNGR1/TLR2/TLR4/LRP1/SKI/PLEC	13
GO:0034765	regulation of ion transmembrane transport	40/1068	491/18722	0.0149952817198961	0.0538353560615832	TMSB4X/CYBA/TREM2/CTSS/HAMP/FXYD5/YWHAH/CD63/SLC8A1/CYBB/IFNGR2/MEF2C/LYN/VMP1/FLNA/CORO1A/P2RX7/PRNP/TCIRG1/PTAFR/KCNAB2/HVCN1/KCNE3/PTPN6/ATP1B1/GLRX/PTK2B/SLC30A1/DAPK1/CALM3/CAB39/GSTO1/CLIC1/KLHL24/RGS2/BAX/WNK1/KIF5B/ATP1B3/PPIF	40
GO:0002011	morphogenesis of an epithelial sheet	8/1068	57/18722	0.0150348690907644	0.0539415914985138	CD44/FLNA/RHOA/HBEGF/NOTCH2/ITGA5/ADAM17/ARHGAP24	8
GO:0010923	negative regulation of phosphatase activity	6/1068	36/18722	0.0152159048433273	0.0545186072606866	LGALS3/NCKAP1L/GNAI2/ROCK1/PPP1R15A/BOD1L1	6
GO:0051385	response to mineralocorticoid	6/1068	36/18722	0.0152159048433273	0.0545186072606866	CYBA/FOS/CYBB/CDKN1A/FOSB/CALM3	6
GO:0032006	regulation of TOR signaling	12/1068	104/18722	0.0153171441619459	0.054830435009053	TREM2/HIF1A/NCKAP1L/DDIT4/RRAGD/GPR137B/TMEM127/LAMTOR4/SESN3/ATM/LAMTOR2/FNIP1	12
GO:1901264	carbohydrate derivative transport	10/1068	80/18722	0.0153232572263996	0.054830435009053	PSAP/NPC2/SLC15A3/PLTP/SLC25A24/SLC25A19/ABCC3/LRRC8C/SLC37A2/ABCG1	10
GO:0045930	negative regulation of mitotic cell cycle	22/1068	235/18722	0.0155488140456639	0.0556006630817774	GPNMB/ZFP36L2/DUSP1/TIMP2/ZFP36L1/RB1/TAOK3/KLF4/TGFB1/PLK3/SLFN11/BCL6/CDKN1A/BTG2/RPS27L/RGCC/BTG1/ATM/FOXN3/APC/DYNC1LI1/TAOK1	22
GO:0097553	calcium ion transmembrane import into cytosol	15/1068	142/18722	0.0156351168128999	0.0558722452466278	CYBA/CCL3/SLC8A1/PTPRC/LYN/CORO1A/PRNP/PTPN6/TRPM2/PTK2B/MCOLN1/ERO1A/CALM3/GSTO1/BAX	15
GO:0046434	organophosphate catabolic process	16/1068	155/18722	0.0157078778272944	0.0560951083759632	APOC1/TYMP/SAMHD1/PLA2G7/UPP1/GPCPD1/NUDT3/DPYD/ENTPD1/PLBD2/HPRT1/MBD4/ACAT1/ABHD12/PLA2G15/PLBD1	16
GO:0060401	cytosolic calcium ion transport	18/1068	182/18722	0.0163066120101588	0.0581261521090003	CYBA/CCL3/SLC8A1/PTPRC/LYN/TMBIM6/CORO1A/P2RX7/PRNP/PTPN6/TRPM2/PTK2B/MCOLN1/ERO1A/CALM3/GSTO1/BAX/MICU1	18
GO:0001915	negative regulation of T cell mediated cytotoxicity	3/1068	10/18722	0.0164182647286004	0.0581261521090003	NCKAP1L/PTPRC/LILRB1	3
GO:0002524	hypersensitivity	3/1068	10/18722	0.0164182647286004	0.0581261521090003	C3/HLA-E/BTK	3
GO:0003330	regulation of extracellular matrix constituent secretion	3/1068	10/18722	0.0164182647286004	0.0581261521090003	TNFRSF1B/RGCC/TNFRSF1A	3
GO:0007028	cytoplasm organization	3/1068	10/18722	0.0164182647286004	0.0581261521090003	ZMIZ1/ETV6/KIF5B	3
GO:0045348	positive regulation of MHC class II biosynthetic process	3/1068	10/18722	0.0164182647286004	0.0581261521090003	TLR4/CIITA/JAK2	3
GO:0070099	regulation of chemokine-mediated signaling pathway	3/1068	10/18722	0.0164182647286004	0.0581261521090003	TREM2/HIF1A/SH2B3	3
GO:0071421	manganese ion transmembrane transport	3/1068	10/18722	0.0164182647286004	0.0581261521090003	SLC11A1/TRPM2/ATP2C1	3
GO:0071803	positive regulation of podosome assembly	3/1068	10/18722	0.0164182647286004	0.0581261521090003	LCP1/MSN/RHOA	3
GO:0098885	modification of postsynaptic actin cytoskeleton	3/1068	10/18722	0.0164182647286004	0.0581261521090003	RHOA/CYFIP1/PFN1	3
GO:1902946	protein localization to early endosome	3/1068	10/18722	0.0164182647286004	0.0581261521090003	SORL1/MSN/DTX3L	3
GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	3/1068	10/18722	0.0164182647286004	0.0581261521090003	WAS/CYFIP1/BRK1	3
GO:0014911	positive regulation of smooth muscle cell migration	7/1068	47/18722	0.0164381964637388	0.0581261521090003	AIF1/DOCK4/TLR4/LRP1/IQGAP1/PAK1/S100A11	7
GO:0032008	positive regulation of TOR signaling	7/1068	47/18722	0.0164381964637388	0.0581261521090003	TREM2/NCKAP1L/RRAGD/GPR137B/LAMTOR4/LAMTOR2/FNIP1	7
GO:0097300	programmed necrotic cell death	7/1068	47/18722	0.0164381964637388	0.0581261521090003	NUPR1/ASAH1/CASP1/ARHGEF2/ALKBH7/BAX/PPIF	7
GO:0002931	response to ischemia	8/1068	58/18722	0.0165956500352045	0.0586444843418229	TREM2/CSF1R/CIB1/EIF4EBP1/P2RX7/BID/EGR1/PPIF	8
GO:0046486	glycerolipid metabolic process	33/1068	392/18722	0.016616549148174	0.0586451769585599	APOE/APOC1/FABP5/GPX1/C3/PLEK/SORL1/CSF1R/PLA2G7/GPCPD1/LPL/PLSCR1/LPCAT2/AGPAT2/ABHD2/LPGAT1/NR1H3/APOBR/INPP5D/OSBPL8/ACSL1/SOCS3/MTMR6/ABHD12/EFR3A/CPT1A/ATM/CEPT1/SERINC1/PLA2G15/ACSL4/PIK3R1/SOCS6	33
GO:0048708	astrocyte differentiation	10/1068	81/18722	0.0166175825740619	0.0586451769585599	VIM/TREM2/C1QA/GRN/C5AR1/ID2/IFNGR1/TLR4/STAT3/LRP1	10
GO:0032088	negative regulation of NF-kappaB transcription factor activity	11/1068	93/18722	0.0166712850632009	0.0587962445758378	TMSB4X/PYCARD/SPI1/HAVCR2/ARRB2/KLF4/ADORA3/IRAK1/IRAK3/TNFAIP3/NFKBIA	11
GO:0034655	nucleobase-containing compound catabolic process	34/1068	407/18722	0.0168959938218591	0.0593079634483143	VIM/TYMP/RNASET2/SAMHD1/ZFP36L2/DNASE2/ZFP36/SLC11A1/ZFP36L1/UPP1/RNASE6/YBX1/NUDT3/DPYD/HSPA1A/OAS2/MGAT1/TNFRSF1B/PABPC1/ENTPD1/APOBEC3C/APOBEC3A/MYD88/BTG2/RNASEH2B/HPRT1/MBD4/ACAT1/ATM/PABPC4/DDX5/ROCK1/BAX/RNH1	34
GO:0007263	nitric oxide mediated signal transduction	5/1068	27/18722	0.0169193190593517	0.0593079634483143	APOE/CD36/FPR1/VEGFA/DDAH2	5
GO:0034377	plasma lipoprotein particle assembly	5/1068	27/18722	0.0169193190593517	0.0593079634483143	APOE/APOC1/SOAT1/ABCA1/PRKACB	5
GO:1903203	regulation of oxidative stress-induced neuron death	5/1068	27/18722	0.0169193190593517	0.0593079634483143	TREM2/HIF1A/TLR4/TRPM2/MCL1	5
GO:0002295	T-helper cell lineage commitment	4/1068	18/18722	0.0169482727274464	0.0593079634483143	IL6R/SPN/STAT6/STAT3	4
GO:0009125	nucleoside monophosphate catabolic process	4/1068	18/18722	0.0169482727274464	0.0593079634483143	TYMP/UPP1/DPYD/HPRT1	4
GO:0044872	lipoprotein localization	4/1068	18/18722	0.0169482727274464	0.0593079634483143	MSR1/CD36/VMP1/LRP1	4
GO:0055070	copper ion homeostasis	4/1068	18/18722	0.0169482727274464	0.0593079634483143	PRNP/SLC31A1/SCO2/XIAP	4
GO:0071786	endoplasmic reticulum tubular network organization	4/1068	18/18722	0.0169482727274464	0.0593079634483143	ATL3/RTN4/RTN3/RAB10	4
GO:0150079	negative regulation of neuroinflammatory response	4/1068	18/18722	0.0169482727274464	0.0593079634483143	TREM2/GRN/PTPRC/TNFRSF1B	4
GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	4/1068	18/18722	0.0169482727274464	0.0593079634483143	ZFP36L2/ZFP36/ZFP36L1/PABPC1	4
GO:1902683	regulation of receptor localization to synapse	4/1068	18/18722	0.0169482727274464	0.0593079634483143	TYROBP/RAP1A/ADAM10/STX7	4
GO:0006904	vesicle docking involved in exocytosis	6/1068	37/18722	0.0173088935959457	0.0604131887734302	PLEK/RAB8B/STXBP2/RAB10/RAB8A/RAB13	6
GO:0060416	response to growth hormone	6/1068	37/18722	0.0173088935959457	0.0604131887734302	LYN/JAK2/STAT5A/STAT6/STAT3/PIK3R1	6
GO:0072529	pyrimidine-containing compound catabolic process	6/1068	37/18722	0.0173088935959457	0.0604131887734302	TYMP/UPP1/DPYD/APOBEC3C/APOBEC3A/MBD4	6
GO:0090218	positive regulation of lipid kinase activity	6/1068	37/18722	0.0173088935959457	0.0604131887734302	CD81/LYN/TGFB1/FGR/PTK2B/CDC42	6
GO:0001837	epithelial to mesenchymal transition	16/1068	157/18722	0.0175507432402557	0.0612177185031801	S100A4/HIF1A/HGF/FLNA/SDCBP/GLIPR2/TGFB1/ENG/TGFBR2/SPRED1/IL1B/RGCC/DDX5/TGFBR1/RTN4/ROCK1	16
GO:0001890	placenta development	15/1068	144/18722	0.0175662006434448	0.061232053405703	SPP1/CTSB/GRB2/JUNB/HIF1A/ZFP36L1/ST14/VASH1/PRDM1/NOTCH2/STK4/SOCS3/CEBPB/HTRA1/CEBPA	15
GO:0035821	modulation of process of other organism	12/1068	106/18722	0.0175960855653524	0.0612966286059662	APOE/IFI27/CCL3/CLEC7A/JUN/CD4/CCL4/SYK/P2RX7/SAP30/IGF2R/CFL1	12
GO:0061564	axon development	38/1068	467/18722	0.0177009375094104	0.0616221024521153	APOE/SPP1/GRN/TSPO/ALCAM/ACTB/SKIL/PLXNC1/DPYSL2/FLNA/TWF2/NR4A2/RHOG/KLF4/VEGFA/PLXND1/JAK2/NOTCH2/ITGA4/ARHGAP4/VASP/S100A6/CYFIP1/RAC1/SHTN1/LRP1/NUMB/RTN4/PAK2/PAK1/SVBP/PICALM/RAB10/DBNL/FLOT1/RAB8A/KIF5B/B3GNT2	38
GO:0051702	biological process involved in interaction with symbiont	11/1068	94/18722	0.0179413069004857	0.0624186280045266	APOE/GPX1/IFI27/CCL3/JUN/CCL4/TREM1/SAP30/MYD88/IGF2R/CFL1	11
GO:0021700	developmental maturation	25/1068	280/18722	0.0179544428118383	0.0624240808071387	C3/C1QA/SNX10/CD63/CLEC7A/RAB32/HIF1A/RB1/RHOA/NR4A2/ATP6AP2/AXL/VEGFA/LYL1/BTK/ABHD2/KLF2/MMP2/LRRK2/PTK2B/CDKN1A/CEBPA/PTBP3/PICALM/PFN1	25
GO:0009205	purine ribonucleoside triphosphate metabolic process	10/1068	82/18722	0.0179910543787633	0.0624708683576621	TMSB4X/TREM2/RHOA/RHOQ/TGFB1/ATP6V1A/LRRK2/IMPDH1/PRKAG2/STAT3	10
GO:0060395	SMAD protein signal transduction	10/1068	82/18722	0.0179910543787633	0.0624708683576621	VIM/FOS/JUN/NCEH1/ZMIZ1/TGFB1/JAK2/LRP1/TGFBR1/SKI	10
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	8/1068	59/18722	0.0182698464427413	0.063398129520921	LILRB4/PTPRC/SAMSN1/CD300A/PTPN6/SH2B3/PARP14/SOCS3	8
GO:0120009	intermembrane lipid transfer	7/1068	48/18722	0.0183262275215502	0.06355290726625	APOE/NPC2/TSPO/PLTP/OSBPL8/ABCG1/ABCA1	7
GO:0061351	neural precursor cell proliferation	15/1068	145/18722	0.0185976415407577	0.0644527127513992	CTSZ/C5AR1/ID2/HIF1A/GNAI2/LYN/FLNA/RHOA/ATF5/VEGFA/LRRK2/ARHGEF2/BTG2/NUMB/RAB10	15
GO:0006470	protein dephosphorylation	25/1068	281/18722	0.0186805504913631	0.0646984919456967	DUSP1/LGALS3/NCKAP1L/PTPRC/GNAI2/CD300A/NCEH1/TGFB1/DUSP23/LILRB2/PTPN6/JAK2/PPM1M/CD33/LRRK2/PTPN18/PTPRJ/DAPP1/MTMR6/PTP4A2/DUSP3/CALM3/ROCK1/PPP1R15A/BOD1L1	25
GO:0009749	response to glucose	20/1068	212/18722	0.0189100789496164	0.0654514342605069	HLA-DRB1/LGALS1/CYBA/TREM2/TXNIP/GLUL/SLC8A1/HIF1A/UCP2/LPL/RHOA/TGFBR2/PTK2B/RAC1/ABCG1/LRP1/LDHA/STX4/EGR1/KIF5B	20
GO:0006163	purine nucleotide metabolic process	33/1068	396/18722	0.0189804571530512	0.0656529146140157	TMSB4X/TREM2/NUPR1/FBP1/SAMHD1/PPT1/HIF1A/PDK4/RHOA/NUDT3/RHOQ/P2RX7/KYNU/TGFB1/DDIT4/ATP6V1A/ACOT9/LRRK2/IMPDH1/PRKAG2/ACSL1/LACC1/ADPGK/PAPSS1/HPRT1/STAT3/ACAT1/LDHA/ADCY7/PGK1/PKM/ACSL4/HSD17B4	33
GO:0030516	regulation of axon extension	11/1068	95/18722	0.0192818784722591	0.0666101256314406	APOE/DPYSL2/TWF2/VEGFA/ARHGAP4/CYFIP1/SHTN1/LRP1/RTN4/PAK1/DBNL	11
GO:1901379	regulation of potassium ion transmembrane transport	11/1068	95/18722	0.0192818784722591	0.0666101256314406	TREM2/CD63/FLNA/PRNP/KCNAB2/KCNE3/ATP1B1/CAB39/KLHL24/WNK1/ATP1B3	11
GO:0007219	Notch signaling pathway	17/1068	172/18722	0.0193069116924994	0.0666539318571508	CFD/BMP2K/ZMIZ1/TGFBR2/DTX3L/NOTCH2/APH1B/BCL6/LFNG/STAT3/NFKBIA/TSPAN14/ADAM17/CEBPA/ADAM10/SPEN/MAML2	17
GO:0035966	response to topologically incorrect protein	16/1068	159/18722	0.0195554146879751	0.0674258083521519	TMBIM6/HSPA1A/SERP1/EIF2AK2/ERO1A/TRAM1/CREBRF/HSPH1/UBE2W/PPP1R15A/DNAJC3/HERPUD1/BAX/ATF3/PIK3R1/SDF2L1	16
GO:0030279	negative regulation of ossification	6/1068	38/18722	0.0195913651793241	0.0674258083521519	CCL3/SRGN/HIF1A/MEF2C/CCR1/PTK2B	6
GO:1903580	positive regulation of ATP metabolic process	6/1068	38/18722	0.0195913651793241	0.0674258083521519	TMSB4X/TREM2/NUPR1/HIF1A/P2RX7/STAT3	6
GO:0009150	purine ribonucleotide metabolic process	31/1068	368/18722	0.0196338174509316	0.0674258083521519	TMSB4X/TREM2/NUPR1/FBP1/PPT1/HIF1A/PDK4/RHOA/NUDT3/RHOQ/P2RX7/KYNU/TGFB1/DDIT4/ATP6V1A/ACOT9/LRRK2/IMPDH1/PRKAG2/ACSL1/ADPGK/PAPSS1/HPRT1/STAT3/ACAT1/LDHA/ADCY7/PGK1/PKM/ACSL4/HSD17B4	31
GO:0010884	positive regulation of lipid storage	5/1068	28/18722	0.0196554478387574	0.0674258083521519	MSR1/C3/PLIN2/CD36/LPL	5
GO:0032438	melanosome organization	5/1068	28/18722	0.0196554478387574	0.0674258083521519	ZEB2/RAB32/BLOC1S1/RAB29/BLOC1S2	5
GO:0032801	receptor catabolic process	5/1068	28/18722	0.0196554478387574	0.0674258083521519	APOE/LAPTM5/LGMN/TGFB1/DTX3L	5
GO:1903649	regulation of cytoplasmic transport	5/1068	28/18722	0.0196554478387574	0.0674258083521519	SORL1/MSN/LRRK2/RAB29/CHMP3	5
GO:1903672	positive regulation of sprouting angiogenesis	5/1068	28/18722	0.0196554478387574	0.0674258083521519	JAK1/KLF4/VEGFA/ITGA5/PKM	5
GO:1990776	response to angiotensin	5/1068	28/18722	0.0196554478387574	0.0674258083521519	CYBA/CYBB/AGTRAP/IQGAP1/ROCK1	5
GO:0008217	regulation of blood pressure	18/1068	186/18722	0.0199136778121142	0.0682682372771081	CYBA/CTSZ/SGK1/SOD2/HMOX1/ID2/SCPEP1/RHOA/ATP6AP2/ANPEP/PTAFR/PTGS1/NAMPT/AGTRAP/ERAP2/PRCP/WNK1/ATP1A1	18
GO:0031102	neuron projection regeneration	8/1068	60/18722	0.0200615258684565	0.0685573106942312	SPP1/GRN/TSPO/HGF/FLNA/KLF4/JAK2/LRP1	8
GO:0031638	zymogen activation	8/1068	60/18722	0.0200615258684565	0.0685573106942312	CTSZ/CTSH/LGMN/PYCARD/IFI16/PLAU/RUNX1/PGK1	8
GO:0042306	regulation of protein import into nucleus	8/1068	60/18722	0.0200615258684565	0.0685573106942312	CD36/FLNA/TGFB1/MDFIC/JAK2/NUP62/HCLS1/PIK3R1	8
GO:0051851	modulation by host of symbiont process	8/1068	60/18722	0.0200615258684565	0.0685573106942312	APOE/IFI27/CCL3/JUN/CCL4/SAP30/IGF2R/CFL1	8
GO:1903670	regulation of sprouting angiogenesis	8/1068	60/18722	0.0200615258684565	0.0685573106942312	GLUL/ALOX5/JAK1/KLF4/VEGFA/KLF2/ITGA5/PKM	8
GO:0007611	learning or memory	23/1068	255/18722	0.0202618164650654	0.0691441216014878	APOE/B2M/TREM2/SGK1/LGMN/FOS/PPT1/JUN/HIF1A/MEF2C/ACTR2/TLR2/PRNP/ATXN1/LILRB2/NQO2/BTG2/CEBPB/PJA2/PICALM/UBE3A/PIAS1/GM2A	23
GO:0043547	positive regulation of GTPase activity	23/1068	255/18722	0.0202618164650654	0.0691441216014878	RGS1/CCL3/CCL3L3/GPR65/LIMS1/RGS10/ADAP2/DOCK10/CCL4/CORO1C/RAP1A/RHOG/PREX1/ABR/TBC1D2/DENND1B/PTK2B/ARAP1/ARHGAP24/PICALM/TBC1D9B/RCC2/S100A10	23
GO:0051099	positive regulation of binding	17/1068	173/18722	0.0203159544859523	0.0691441216014878	APOE/B2M/PLAUR/RB1/KLF4/PARP9/PLXND1/TGFB1/DTX3L/JAK2/LRRK2/STK4/LRP1/CALM3/SKI/FLOT1/S100A10	17
GO:0009395	phospholipid catabolic process	7/1068	49/18722	0.0203613805086665	0.0691441216014878	APOC1/PLA2G7/GPCPD1/PLBD2/ABHD12/PLA2G15/PLBD1	7
GO:0009409	response to cold	7/1068	49/18722	0.0203613805086665	0.0691441216014878	SOD2/FOS/UCP2/LPL/METRNL/NFKBIA/DNAJC3	7
GO:0032692	negative regulation of interleukin-1 production	7/1068	49/18722	0.0203613805086665	0.0691441216014878	TREM2/ACP5/LILRB4/ARRB2/CARD16/CD33/TNFAIP3	7
GO:0042304	regulation of fatty acid biosynthetic process	7/1068	49/18722	0.0203613805086665	0.0691441216014878	APOC1/CD74/FABP5/PDK4/LPGAT1/NR1H3/IL1B	7
GO:0070169	positive regulation of biomineral tissue development	7/1068	49/18722	0.0203613805086665	0.0691441216014878	ISG15/SLC8A1/MEF2C/ALOX5/P2RX7/TGFB1/CEBPB	7
GO:1904752	regulation of vascular associated smooth muscle cell migration	7/1068	49/18722	0.0203613805086665	0.0691441216014878	DOCK4/MEF2C/RHOA/GNA13/LRP1/IQGAP1/PAK1	7
GO:1990928	response to amino acid starvation	7/1068	49/18722	0.0203613805086665	0.0691441216014878	UCP2/EIF4EBP1/RRAGD/CDKN1A/EIF2AK2/SESN3/ATF3	7
GO:0002791	regulation of peptide secretion	19/1068	200/18722	0.0203742029174127	0.0691441502782132	HLA-DRB1/CD74/GLUL/HIF1A/UCP2/ALOX5/TCIRG1/JAK2/TRPM2/RAB8B/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/STX4/ACSL4/KIF5B	19
GO:0008356	asymmetric cell division	4/1068	19/18722	0.0205199413023394	0.0692467812804399	ACTR2/ACTR3/ARHGEF2/RAB10	4
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	4/1068	19/18722	0.0205199413023394	0.0692467812804399	TYMP/UPP1/DPYD/MBD4	4
GO:0010744	positive regulation of macrophage derived foam cell differentiation	4/1068	19/18722	0.0205199413023394	0.0692467812804399	MSR1/IL18/CD36/LPL	4
GO:0031065	positive regulation of histone deacetylation	4/1068	19/18722	0.0205199413023394	0.0692467812804399	VEGFA/JDP2/BCL6/LRRK2	4
GO:0035313	wound healing, spreading of epidermal cells	4/1068	19/18722	0.0205199413023394	0.0692467812804399	HBEGF/ITGA5/ADAM17/ARHGAP24	4
GO:0043031	negative regulation of macrophage activation	4/1068	19/18722	0.0205199413023394	0.0692467812804399	GRN/PTPRC/VSIG4/NR1H3	4
GO:0045780	positive regulation of bone resorption	4/1068	19/18722	0.0205199413023394	0.0692467812804399	SPP1/SYK/ADAM8/ATP6AP1	4
GO:0046782	regulation of viral transcription	4/1068	19/18722	0.0205199413023394	0.0692467812804399	ZFP36/IFITM3/MDFIC/TRIM14	4
GO:1903975	regulation of glial cell migration	4/1068	19/18722	0.0205199413023394	0.0692467812804399	TREM2/CCL3/GPR183/LRP1	4
GO:0043500	muscle adaptation	13/1068	121/18722	0.0206035222966036	0.0694853789452955	CYBA/AIF1/HAMP/MEF2A/HMOX1/TNFRSF1B/KLF4/IL1B/TNFRSF1A/ROCK1/GSN/PAK1/RGS2	13
GO:0071479	cellular response to ionizing radiation	9/1068	72/18722	0.0208456994682455	0.0702582100753607	CYBA/HAMP/IFI16/GRB2/NAMPT/CDKN1A/ATM/RHOB/EGR1	9
GO:0051960	regulation of nervous system development	36/1068	443/18722	0.0209079662848205	0.0704240861878224	SPP1/B2M/TYMP/TREM2/CXCR4/TSPO/SORL1/YWHAH/ID2/CTSC/SKIL/HIF1A/LYN/HGF/ACTR2/PLXNC1/TWF2/TLR2/ITGAX/TNFRSF1B/VEGFA/PLXND1/TGFB1/ARHGAP4/IL1B/CYFIP1/SHTN1/LRP1/NUMB/RTN4/PAK1/BHLHE40/SKI/SPEN/DBNL/BHLHE41	36
GO:0045445	myoblast differentiation	10/1068	84/18722	0.0209858628706214	0.070642368091	LGALS1/IL18/MEF2C/ZFP36L1/RB1/MBNL1/TGFB1/BTG1/DDX5/PLEC	10
GO:0045786	negative regulation of cell cycle	32/1068	385/18722	0.0213250581695868	0.0717394101515527	GPNMB/NUPR1/ZFP36L2/DUSP1/TIMP2/ZFP36L1/RB1/TAOK3/ATF5/LILRB1/KLF4/TGFB1/PLK3/SLFN11/BCL6/CDKN1A/BTG2/RNASEH2B/RPS27L/TNFAIP3/RGCC/BTG1/ATM/PRKAR1A/FOXN3/PRKACB/APC/CEBPA/RHOB/NR4A1/DYNC1LI1/TAOK1	32
GO:0006054	N-acetylneuraminate metabolic process	3/1068	11/18722	0.0216321669898916	0.072053810541639	GNPDA1/NPL/NAGK	3
GO:0007042	lysosomal lumen acidification	3/1068	11/18722	0.0216321669898916	0.072053810541639	GRN/PPT1/ATP6AP2	3
GO:0034975	protein folding in endoplasmic reticulum	3/1068	11/18722	0.0216321669898916	0.072053810541639	ERO1A/CANX/DNAJC3	3
GO:0039530	MDA-5 signaling pathway	3/1068	11/18722	0.0216321669898916	0.072053810541639	IRF7/OAS3/IFIH1	3
GO:0042789	mRNA transcription by RNA polymerase II	3/1068	11/18722	0.0216321669898916	0.072053810541639	C5AR1/FLNA/STAT3	3
GO:0045060	negative thymic T cell selection	3/1068	11/18722	0.0216321669898916	0.072053810541639	CD74/PTPRC/DOCK2	3
GO:0045628	regulation of T-helper 2 cell differentiation	3/1068	11/18722	0.0216321669898916	0.072053810541639	CD86/IL18/BCL6	3
GO:0048102	autophagic cell death	3/1068	11/18722	0.0216321669898916	0.072053810541639	LAPTM5/TREM2/LAMP1	3
GO:0048680	positive regulation of axon regeneration	3/1068	11/18722	0.0216321669898916	0.072053810541639	GRN/FLNA/LRP1	3
GO:0051132	NK T cell activation	3/1068	11/18722	0.0216321669898916	0.072053810541639	IL18/CD300A/HSPH1	3
GO:0071888	macrophage apoptotic process	3/1068	11/18722	0.0216321669898916	0.072053810541639	MEF2C/PLEKHO2/IRF7	3
GO:0097494	regulation of vesicle size	3/1068	11/18722	0.0216321669898916	0.072053810541639	RIN3/PICALM/CHMP3	3
GO:1900426	positive regulation of defense response to bacterium	3/1068	11/18722	0.0216321669898916	0.072053810541639	CYBA/GRN/HAVCR2	3
GO:1902337	regulation of apoptotic process involved in morphogenesis	3/1068	11/18722	0.0216321669898916	0.072053810541639	TNFRSF1B/TNFRSF1A/BAX	3
GO:1905668	positive regulation of protein localization to endosome	3/1068	11/18722	0.0216321669898916	0.072053810541639	SORL1/MSN/DTX3L	3
GO:2000644	regulation of receptor catabolic process	3/1068	11/18722	0.0216321669898916	0.072053810541639	APOE/LAPTM5/DTX3L	3
GO:0071695	anatomical structure maturation	21/1068	229/18722	0.0218539469282006	0.0727476234574773	C3/C1QA/SNX10/CLEC7A/HIF1A/RB1/RHOA/NR4A2/ATP6AP2/AXL/VEGFA/LYL1/BTK/ABHD2/KLF2/MMP2/LRRK2/PTK2B/CDKN1A/CEBPA/PTBP3	21
GO:0051384	response to glucocorticoid	15/1068	148/18722	0.0219697895665855	0.0730881532067173	AIF1/ZFP36L2/FOS/DUSP1/ZFP36/ZFP36L1/HNMT/RHOA/DDIT4/PTAFR/CDKN1A/ADAM9/FOSB/CALM3/NR3C1	15
GO:0032506	cytokinetic process	6/1068	39/18722	0.022070272981182	0.0733320153980654	RHOA/KLHDC8B/NUP62/CHMP3/PLEC/CHMP1B	6
GO:0045622	regulation of T-helper cell differentiation	6/1068	39/18722	0.022070272981182	0.0733320153980654	HLA-DRA/HLA-DRB1/CD86/IL18/BCL6/NFKBIZ	6
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	11/1068	97/18722	0.022183214598546	0.0736619236761566	GPX1/HMOX1/LGALS3/HGF/PEA15/HSPA1A/ARHGEF2/MCL1/IL1B/TNFAIP3/TGFBR1	11
GO:0090087	regulation of peptide transport	19/1068	202/18722	0.0223490901566204	0.0741670913192642	HLA-DRB1/CD74/GLUL/HIF1A/UCP2/ALOX5/TCIRG1/JAK2/TRPM2/RAB8B/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/STX4/ACSL4/KIF5B	19
GO:0072521	purine-containing compound metabolic process	34/1068	416/18722	0.0225355016836157	0.0743050912394539	TMSB4X/TREM2/NUPR1/FBP1/SAMHD1/PPT1/HIF1A/PDK4/RHOA/NUDT3/DPYD/RHOQ/P2RX7/KYNU/TGFB1/DDIT4/ATP6V1A/ACOT9/LRRK2/IMPDH1/PRKAG2/ACSL1/LACC1/ADPGK/PAPSS1/HPRT1/STAT3/ACAT1/LDHA/ADCY7/PGK1/PKM/ACSL4/HSD17B4	34
GO:0002639	positive regulation of immunoglobulin production	7/1068	50/18722	0.0225487354709306	0.0743050912394539	HLA-E/CD86/PTPRC/TGFB1/SASH3/STAT6/STX4	7
GO:0046460	neutral lipid biosynthetic process	7/1068	50/18722	0.0225487354709306	0.0743050912394539	C3/LPL/LPGAT1/NR1H3/ACSL1/PLA2G15/ACSL4	7
GO:0046463	acylglycerol biosynthetic process	7/1068	50/18722	0.0225487354709306	0.0743050912394539	C3/LPL/LPGAT1/NR1H3/ACSL1/PLA2G15/ACSL4	7
GO:0110151	positive regulation of biomineralization	7/1068	50/18722	0.0225487354709306	0.0743050912394539	ISG15/SLC8A1/MEF2C/ALOX5/P2RX7/TGFB1/CEBPB	7
GO:1904738	vascular associated smooth muscle cell migration	7/1068	50/18722	0.0225487354709306	0.0743050912394539	DOCK4/MEF2C/RHOA/GNA13/LRP1/IQGAP1/PAK1	7
GO:0002637	regulation of immunoglobulin production	9/1068	73/18722	0.0226164385431134	0.0743050912394539	HLA-E/CD86/PTPRC/TMBIM6/TGFB1/SASH3/BCL6/STAT6/STX4	9
GO:0002360	T cell lineage commitment	5/1068	29/18722	0.0226660823165569	0.0743050912394539	RHOA/IL6R/SPN/STAT6/STAT3	5
GO:0010955	negative regulation of protein processing	5/1068	29/18722	0.0226660823165569	0.0743050912394539	CTSZ/PRNP/CARD16/LRRK2/XIAP	5
GO:0019082	viral protein processing	5/1068	29/18722	0.0226660823165569	0.0743050912394539	MGAT4A/MGAT1/PARP9/SPCS3/CANX	5
GO:0032366	intracellular sterol transport	5/1068	29/18722	0.0226660823165569	0.0743050912394539	NPC2/ABCG1/ABCA1/ARL8B/SCP2	5
GO:0032367	intracellular cholesterol transport	5/1068	29/18722	0.0226660823165569	0.0743050912394539	NPC2/ABCG1/ABCA1/ARL8B/SCP2	5
GO:0033028	myeloid cell apoptotic process	5/1068	29/18722	0.0226660823165569	0.0743050912394539	MEF2C/PLEKHO2/IRF7/ADAM17/ARF6	5
GO:0034067	protein localization to Golgi apparatus	5/1068	29/18722	0.0226660823165569	0.0743050912394539	SORL1/ARL5A/VPS13C/GBP5/TMED10	5
GO:0048679	regulation of axon regeneration	5/1068	29/18722	0.0226660823165569	0.0743050912394539	SPP1/GRN/FLNA/KLF4/LRP1	5
GO:0048753	pigment granule organization	5/1068	29/18722	0.0226660823165569	0.0743050912394539	ZEB2/RAB32/BLOC1S1/RAB29/BLOC1S2	5
GO:0060969	negative regulation of gene silencing	5/1068	29/18722	0.0226660823165569	0.0743050912394539	NEAT1/TGFB1/NCOR2/STAT3/ADAR	5
GO:0095500	acetylcholine receptor signaling pathway	5/1068	29/18722	0.0226660823165569	0.0743050912394539	RGS10/GNAI2/GNA15/GNB1/GNAQ	5
GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	5/1068	29/18722	0.0226660823165569	0.0743050912394539	GPX1/TREM2/SOD2/HIF1A/MCL1	5
GO:1903318	negative regulation of protein maturation	5/1068	29/18722	0.0226660823165569	0.0743050912394539	CTSZ/PRNP/CARD16/LRRK2/XIAP	5
GO:0061387	regulation of extent of cell growth	12/1068	110/18722	0.0229049524522668	0.0750425764617072	APOE/SPP1/DPYSL2/TWF2/VEGFA/ARHGAP4/CYFIP1/SHTN1/LRP1/RTN4/PAK1/DBNL	12
GO:0045834	positive regulation of lipid metabolic process	15/1068	149/18722	0.0231903655304854	0.0759315609238466	APOE/APOC1/CD74/CD81/LYN/TGFB1/CREBL2/LPGAT1/NR1H3/FGR/PTK2B/IL1B/ABCG1/CPT1A/CDC42	15
GO:0006913	nucleocytoplasmic transport	26/1068	301/18722	0.0233178699461786	0.0762565007451999	TXNIP/IFI27/CD36/FLNA/NUP214/SYK/MX2/SP100/ATXN1/TGFB1/MDFIC/JAK2/LRRK2/CDKN1A/IL1B/STAT3/KPNA3/NFKBIA/NUP62/HCLS1/UHMK1/AKAP13/RANBP2/APPL1/PIK3R1/KPNB1	26
GO:0051169	nuclear transport	26/1068	301/18722	0.0233178699461786	0.0762565007451999	TXNIP/IFI27/CD36/FLNA/NUP214/SYK/MX2/SP100/ATXN1/TGFB1/MDFIC/JAK2/LRRK2/CDKN1A/IL1B/STAT3/KPNA3/NFKBIA/NUP62/HCLS1/UHMK1/AKAP13/RANBP2/APPL1/PIK3R1/KPNB1	26
GO:0045727	positive regulation of translation	14/1068	136/18722	0.0233327812065562	0.0762590474806645	VIM/RHOA/PABPC1/PTAFR/PTK2B/SERP1/MIF4GD/RPS27L/PPP1R15A/EIF2S3/DNAJC3/PKM/UHMK1/CNBP	14
GO:0048638	regulation of developmental growth	28/1068	330/18722	0.0235725065460723	0.0769959112122314	APOE/SPP1/HAMP/CXCR4/LGMN/MEF2C/DPYSL2/TWF2/VEGFA/TGFBR2/RUNX1/SASH3/STAT5A/ARHGAP4/ITSN2/STK4/CDKN1A/SGPL1/CYFIP1/SERP1/STAT3/SHTN1/LRP1/TGFBR1/RTN4/PAK1/RGS2/DBNL	28
GO:0010573	vascular endothelial growth factor production	8/1068	62/18722	0.0240129805631389	0.0783398084151737	C3/C5AR1/C3AR1/HIF1A/TGFB1/HPSE/IL6R/IL1B	8
GO:0060135	maternal process involved in female pregnancy	8/1068	62/18722	0.0240129805631389	0.0783398084151737	SPP1/CTSB/HAVCR2/LGALS9/JUNB/PRDM1/ADCY7/RGS2	8
GO:0072331	signal transduction by p53 class mediator	16/1068	163/18722	0.0240836921321074	0.0785230228065569	CD74/SGK1/NUPR1/CD44/PYCARD/IFI16/SP100/DDIT4/PLK3/SPRED1/CDKN1A/RPS27L/ATM/DDX5/ZNF385A/BAX	16
GO:0001938	positive regulation of endothelial cell proliferation	12/1068	111/18722	0.0243990768684164	0.0792749995953365	CYBA/HMOX1/HIF1A/VEGFA/TNFSF12/STAT5A/ITGA4/STAT3/VEGFB/TGFBR1/ADAM17/NR4A1	12
GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	12/1068	111/18722	0.0243990768684164	0.0792749995953365	TREM2/IL18/HCST/HGF/KLF4/PIK3AP1/NCF1/PTPN6/JAK2/FGR/HCLS1/UBE3A	12
GO:1901888	regulation of cell junction assembly	19/1068	204/18722	0.0244672578683249	0.0792749995953365	LIMS1/MEF2C/RHOA/CORO1C/TLR2/RAP1A/VEGFA/ABI3/PTPRJ/IL1B/RAC1/LRP1/DUSP3/IQGAP1/ROCK1/ARF6/RCC2/FLOT1/S100A10	19
GO:0051881	regulation of mitochondrial membrane potential	9/1068	74/18722	0.0244921859940929	0.0792749995953365	TSPO/UCP2/CASP1/BID/LRRK2/BNIP3L/PPP2R3C/CLIC1/BAX	9
GO:1903201	regulation of oxidative stress-induced cell death	9/1068	74/18722	0.0244921859940929	0.0792749995953365	GPX1/TREM2/SOD2/HIF1A/HGF/TLR4/TRPM2/LRRK2/MCL1	9
GO:0003159	morphogenesis of an endothelium	4/1068	20/18722	0.0245200100675716	0.0792749995953365	CXCR4/RHOA/ITGAX/RHOB	4
GO:0009110	vitamin biosynthetic process	4/1068	20/18722	0.0245200100675716	0.0792749995953365	PLTP/CYP27A1/PDXK/AKR1A1	4
GO:0010042	response to manganese ion	4/1068	20/18722	0.0245200100675716	0.0792749995953365	TSPO/SOD2/LRRK2/ADAM9	4
GO:0032495	response to muramyl dipeptide	4/1068	20/18722	0.0245200100675716	0.0792749995953365	VIM/ARHGEF2/TNFAIP3/NFKBIA	4
GO:0043011	myeloid dendritic cell differentiation	4/1068	20/18722	0.0245200100675716	0.0792749995953365	SPI1/TGFBR2/NOTCH2/LTBR	4
GO:0046629	gamma-delta T cell activation	4/1068	20/18722	0.0245200100675716	0.0792749995953365	NCKAP1L/PTPRC/SYK/LILRB1	4
GO:0061154	endothelial tube morphogenesis	4/1068	20/18722	0.0245200100675716	0.0792749995953365	CXCR4/RHOA/ITGAX/RHOB	4
GO:0071243	cellular response to arsenic-containing substance	4/1068	20/18722	0.0245200100675716	0.0792749995953365	HMOX1/GSTO1/ATF3/PPIF	4
GO:0090201	negative regulation of release of cytochrome c from mitochondria	4/1068	20/18722	0.0245200100675716	0.0792749995953365	GPX1/ARRB2/HGF/PPIF	4
GO:0006986	response to unfolded protein	14/1068	137/18722	0.0246772536080649	0.0796945024971809	TMBIM6/HSPA1A/SERP1/EIF2AK2/ERO1A/TRAM1/CREBRF/HSPH1/PPP1R15A/DNAJC3/HERPUD1/BAX/ATF3/PIK3R1	14
GO:0010508	positive regulation of autophagy	13/1068	124/18722	0.0246793020149721	0.0796945024971809	MTDH/HMOX1/HIF1A/TRIM22/BID/PLK3/TRIM14/LRRK2/BNIP3L/TRIM38/DAPK1/SESN3/ROCK1	13
GO:0030501	positive regulation of bone mineralization	6/1068	40/18722	0.0247520953057946	0.0797633008469915	ISG15/SLC8A1/MEF2C/ALOX5/P2RX7/TGFB1	6
GO:0043001	Golgi to plasma membrane protein transport	6/1068	40/18722	0.0247520953057946	0.0797633008469915	VAMP5/GGA2/CSK/ATP2C1/GGA1/RAB10	6
GO:1901998	toxin transport	6/1068	40/18722	0.0247520953057946	0.0797633008469915	CASP1/GGA1/ATP6V0A1/RAB29/ABCG1/ADAM10	6
GO:0098739	import across plasma membrane	17/1068	177/18722	0.0247597347884935	0.0797633008469915	SLC8A1/CD36/SLC15A3/PRNP/LRRC8C/TRPM2/SLC6A6/ATP1B1/ACSL1/SLC2A3/SLC31A1/SLC30A1/SLC1A3/RGS2/WNK1/ATP1B3/ATP1A1	17
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	7/1068	51/18722	0.024893124994405	0.0801451685380723	TREM2/PYCARD/STAT1/LILRB4/RHOA/TNFAIP3/CARD19	7
GO:0006165	nucleoside diphosphate phosphorylation	11/1068	99/18722	0.0253920519364458	0.0817027502975918	NUPR1/FBP1/HIF1A/P2RX7/DDIT4/PRKAG2/ADPGK/STAT3/LDHA/PGK1/PKM	11
GO:0044282	small molecule catabolic process	31/1068	376/18722	0.0255611312143734	0.0821977735594511	APOE/GLUL/SDS/ALDH2/HNMT/UPP1/NUDT3/IL4I1/DPYD/MGAT1/DDAH2/SDSL/CYP27A1/KYNU/GNPDA1/ACAA2/GLS/NQO2/ABHD2/APOBEC3C/APOBEC3A/SRD5A3/AKR1A1/ACAT1/CPT1A/FAH/NPL/NAGK/PLA2G15/SCP2/HSD17B4	31
GO:1904064	positive regulation of cation transmembrane transport	15/1068	151/18722	0.0257832670358095	0.0828627212181228	TMSB4X/TREM2/CTSS/IFNGR2/VMP1/FLNA/KCNE3/ATP1B1/GLRX/CALM3/GSTO1/BAX/WNK1/KIF5B/ATP1B3	15
GO:0008209	androgen metabolic process	5/1068	30/18722	0.025959822410634	0.0831446802781765	SPP1/HSD17B11/SRD5A3/SGPL1/HSD17B4	5
GO:0009264	deoxyribonucleotide catabolic process	5/1068	30/18722	0.025959822410634	0.0831446802781765	TYMP/SAMHD1/UPP1/DPYD/MBD4	5
GO:0032480	negative regulation of type I interferon production	5/1068	30/18722	0.025959822410634	0.0831446802781765	PYCARD/HAVCR2/REL/SIRPA/LILRB1	5
GO:0070498	interleukin-1-mediated signaling pathway	5/1068	30/18722	0.025959822410634	0.0831446802781765	IRAK1/IRAK3/MYD88/IL1B/EGR1	5
GO:0090314	positive regulation of protein targeting to membrane	5/1068	30/18722	0.025959822410634	0.0831446802781765	ITGB2/CIB1/PRNP/ITGAM/PAK1	5
GO:0001676	long-chain fatty acid metabolic process	12/1068	112/18722	0.0259634518659613	0.0831446802781765	GPX1/ALOX5/TBXAS1/PTGS1/LTC4S/ACSL1/GPX4/QKI/ABHD12/CPT1A/ACSL4/SCP2	12
GO:2000177	regulation of neural precursor cell proliferation	10/1068	87/18722	0.0261356145952928	0.0836463679455514	CTSZ/ID2/HIF1A/GNAI2/LYN/FLNA/RHOA/VEGFA/LRRK2/BTG2	10
GO:1904589	regulation of protein import	8/1068	63/18722	0.0261802257774224	0.0837394773532729	CD36/FLNA/TGFB1/MDFIC/JAK2/NUP62/HCLS1/PIK3R1	8
GO:0008202	steroid metabolic process	27/1068	319/18722	0.0265531198376721	0.084881892561658	APOE/APOC1/SPP1/NPC2/LIPA/TSPO/ASAH1/YWHAH/LGMN/SOAT1/HSD17B11/CYP27A1/OSBPL1A/ACAA2/APOBR/SRD5A3/PRKAG2/SGPL1/ABCG1/ACAT1/ABCA1/DHRS4/CEBPA/SCP2/EGR1/ATP1A1/HSD17B4	27
GO:0048588	developmental cell growth	21/1068	234/18722	0.0269453365530283	0.0860846868206872	APOE/SPP1/HAMP/CXCR4/ALCAM/DPYSL2/TWF2/VEGFA/TGFBR2/ITGA4/ARHGAP4/ITSN2/CYFIP1/SHTN1/LRP1/IQGAP1/RTN4/PAK1/AKAP13/RGS2/DBNL	21
GO:0061640	cytoskeleton-dependent cytokinesis	11/1068	100/18722	0.0271168519462323	0.0865813805336507	ACTR2/ACTR3/RHOA/KLHDC8B/ROCK1/APC/NUP62/RHOB/CHMP3/PLEC/CHMP1B	11
GO:1901991	negative regulation of mitotic cell cycle phase transition	17/1068	179/18722	0.0272390819954778	0.0869202167046707	GPNMB/ZFP36L2/DUSP1/ZFP36L1/RB1/TAOK3/KLF4/PLK3/SLFN11/CDKN1A/RPS27L/RGCC/ATM/FOXN3/APC/DYNC1LI1/TAOK1	17
GO:0031103	axon regeneration	7/1068	52/18722	0.0273991142884706	0.0869740967928967	SPP1/GRN/TSPO/FLNA/KLF4/JAK2/LRP1	7
GO:0048260	positive regulation of receptor-mediated endocytosis	7/1068	52/18722	0.0273991142884706	0.0869740967928967	B2M/C3/PPT1/CD63/ARRB2/SYK/VEGFA	7
GO:0060147	regulation of posttranscriptional gene silencing	7/1068	52/18722	0.0273991142884706	0.0869740967928967	ZFP36/NEAT1/TGFB1/NCOR2/STAT3/ADAR/DDX5	7
GO:1903426	regulation of reactive oxygen species biosynthetic process	7/1068	52/18722	0.0273991142884706	0.0869740967928967	CYBA/SOD2/CD36/RHOA/ALOX5/TLR4/STAT3	7
GO:0045598	regulation of fat cell differentiation	14/1068	139/18722	0.0275376094153445	0.0869740967928967	ZFP36L2/ZFP36/ID2/ZFP36L1/LPL/METRNL/ALOX5/TGFB1/CREBL2/JDP2/STK4/CEBPB/CEBPA/ZNF385A	14
GO:0046034	ATP metabolic process	24/1068	277/18722	0.0275725307737682	0.0869740967928967	TMSB4X/TREM2/NUPR1/TSPO/FBP1/CHCHD10/HIF1A/RHOA/ATP6V1B2/HSPA1A/P2RX7/TGFB1/DDIT4/ATP6V1A/BID/FAM20C/ATP1B1/PRKAG2/ADPGK/STAT3/LDHA/PGK1/PKM/PPIF	24
GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process	3/1068	12/18722	0.0276419990692402	0.0869740967928967	TYMP/UPP1/DPYD	3
GO:0032621	interleukin-18 production	3/1068	12/18722	0.0276419990692402	0.0869740967928967	CD84/TLR2/GBP5	3
GO:0032661	regulation of interleukin-18 production	3/1068	12/18722	0.0276419990692402	0.0869740967928967	CD84/TLR2/GBP5	3
GO:0032736	positive regulation of interleukin-13 production	3/1068	12/18722	0.0276419990692402	0.0869740967928967	HLA-E/IL18/LGALS9	3
GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	3/1068	12/18722	0.0276419990692402	0.0869740967928967	IFI35/NR1H3/NINJ1	3
GO:0035739	CD4-positive, alpha-beta T cell proliferation	3/1068	12/18722	0.0276419990692402	0.0869740967928967	CD81/LGALS9/TGFBR2	3
GO:0043129	surfactant homeostasis	3/1068	12/18722	0.0276419990692402	0.0869740967928967	CTSH/OAS1/VEGFA	3
GO:0043383	negative T cell selection	3/1068	12/18722	0.0276419990692402	0.0869740967928967	CD74/PTPRC/DOCK2	3
GO:0045916	negative regulation of complement activation	3/1068	12/18722	0.0276419990692402	0.0869740967928967	A2M/VSIG4/SERPING1	3
GO:0051549	positive regulation of keratinocyte migration	3/1068	12/18722	0.0276419990692402	0.0869740967928967	HBEGF/ADAM9/ARF6	3
GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress	3/1068	12/18722	0.0276419990692402	0.0869740967928967	JUN/TMBIM6/HSPA1A	3
GO:1904748	regulation of apoptotic process involved in development	3/1068	12/18722	0.0276419990692402	0.0869740967928967	TNFRSF1B/TNFRSF1A/BAX	3
GO:1905666	regulation of protein localization to endosome	3/1068	12/18722	0.0276419990692402	0.0869740967928967	SORL1/MSN/DTX3L	3
GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation	3/1068	12/18722	0.0276419990692402	0.0869740967928967	CD81/LGALS9/TGFBR2	3
GO:2000727	positive regulation of cardiac muscle cell differentiation	3/1068	12/18722	0.0276419990692402	0.0869740967928967	MEF2C/ARRB2/TGFB1	3
GO:2001214	positive regulation of vasculogenesis	3/1068	12/18722	0.0276419990692402	0.0869740967928967	RAP1A/RIN2/RRAS	3
GO:0050691	regulation of defense response to virus by host	6/1068	41/18722	0.0276428050407372	0.0869740967928967	PYCARD/STAT1/LILRB1/PARP9/DTX3L/TNFAIP3	6
GO:1905314	semi-lunar valve development	6/1068	41/18722	0.0276428050407372	0.0869740967928967	RB1/TNFRSF1B/TGFB1/NOTCH2/TNFRSF1A/ROCK1	6
GO:0003018	vascular process in circulatory system	23/1068	263/18722	0.0278094083613838	0.0874473004184305	APOE/FABP5/GPX1/SOD2/SLC8A1/CD36/DOCK4/SLCO2B1/SCPEP1/RHOA/TBXAS1/VEGFA/TGFB1/ABCC3/KLF2/SLC6A6/SLC2A3/PTPRJ/LRP1/ROCK1/SLC1A3/RGS2/PLEC	23
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	8/1068	64/18722	0.0284798676173897	0.0894513187796477	HLA-DRB1/HIF1A/UCP2/RAC1/ABCG1/LRP1/STX4/KIF5B	8
GO:1903409	reactive oxygen species biosynthetic process	8/1068	64/18722	0.0284798676173897	0.0894513187796477	CYBA/SOD2/CD36/RHOA/ALOX5/TLR4/NCF1/STAT3	8
GO:0022898	regulation of transmembrane transporter activity	24/1068	278/18722	0.0286122259986749	0.0898147594466839	TMSB4X/TREM2/CTSS/FXYD5/YWHAH/ACTB/IFNGR2/MEF2C/VMP1/PRNP/PTAFR/KCNE3/ATP1B1/GLRX/PTK2B/DAPK1/CALM3/CAB39/GSTO1/KLHL24/WNK1/KIF5B/ATP1B3/PPIF	24
GO:0046939	nucleotide phosphorylation	11/1068	101/18722	0.0289245174417572	0.0904798286607607	NUPR1/FBP1/HIF1A/P2RX7/DDIT4/PRKAG2/ADPGK/STAT3/LDHA/PGK1/PKM	11
GO:0006244	pyrimidine nucleotide catabolic process	4/1068	21/18722	0.0289582401959106	0.0904798286607607	TYMP/UPP1/DPYD/MBD4	4
GO:0007252	I-kappaB phosphorylation	4/1068	21/18722	0.0289582401959106	0.0904798286607607	TLR7/TLR2/SIRPA/TLR4	4
GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	4/1068	21/18722	0.0289582401959106	0.0904798286607607	GMFG/WAS/CYFIP1/BRK1	4
GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	4/1068	21/18722	0.0289582401959106	0.0904798286607607	IL6R/SPN/STAT6/STAT3	4
GO:0045056	transcytosis	4/1068	21/18722	0.0289582401959106	0.0904798286607607	FCGRT/PTAFR/LRP1/PICALM	4
GO:0090026	positive regulation of monocyte chemotaxis	4/1068	21/18722	0.0289582401959106	0.0904798286607607	AIF1/LGMN/PLA2G7/CCR1	4
GO:1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	4/1068	21/18722	0.0289582401959106	0.0904798286607607	CHCHD10/HSPA1A/ACAA2/SLC35F6	4
GO:0001516	prostaglandin biosynthetic process	5/1068	31/18722	0.0295441619132483	0.0915682353152714	CD74/FABP5/TBXAS1/PTGS1/IL1B	5
GO:0002230	positive regulation of defense response to virus by host	5/1068	31/18722	0.0295441619132483	0.0915682353152714	PYCARD/STAT1/LILRB1/PARP9/DTX3L	5
GO:0031063	regulation of histone deacetylation	5/1068	31/18722	0.0295441619132483	0.0915682353152714	VEGFA/JDP2/BCL6/LRRK2/SKI	5
GO:0033238	regulation of cellular amine metabolic process	5/1068	31/18722	0.0295441619132483	0.0915682353152714	ITGB2/SLC7A7/NR4A2/ITGAM/HPRT1	5
GO:0034656	nucleobase-containing small molecule catabolic process	5/1068	31/18722	0.0295441619132483	0.0915682353152714	UPP1/DPYD/MGAT1/APOBEC3C/APOBEC3A	5
GO:0036475	neuron death in response to oxidative stress	5/1068	31/18722	0.0295441619132483	0.0915682353152714	TREM2/HIF1A/TLR4/TRPM2/MCL1	5
GO:0043171	peptide catabolic process	5/1068	31/18722	0.0295441619132483	0.0915682353152714	CTSH/LTA4H/TPP1/ANPEP/ERAP2	5
GO:0046386	deoxyribose phosphate catabolic process	5/1068	31/18722	0.0295441619132483	0.0915682353152714	TYMP/SAMHD1/UPP1/DPYD/MBD4	5
GO:0046457	prostanoid biosynthetic process	5/1068	31/18722	0.0295441619132483	0.0915682353152714	CD74/FABP5/TBXAS1/PTGS1/IL1B	5
GO:0065005	protein-lipid complex assembly	5/1068	31/18722	0.0295441619132483	0.0915682353152714	APOE/APOC1/SOAT1/ABCA1/PRKACB	5
GO:0070723	response to cholesterol	5/1068	31/18722	0.0295441619132483	0.0915682353152714	CCL3/TGFB1/TGFBR2/ABCA1/TGFBR1	5
GO:0090162	establishment of epithelial cell polarity	5/1068	31/18722	0.0295441619132483	0.0915682353152714	MSN/RHOA/CYTH1/ARF6/CDC42	5
GO:1905144	response to acetylcholine	5/1068	31/18722	0.0295441619132483	0.0915682353152714	RGS10/GNAI2/GNA15/GNB1/GNAQ	5
GO:1905145	cellular response to acetylcholine	5/1068	31/18722	0.0295441619132483	0.0915682353152714	RGS10/GNAI2/GNA15/GNB1/GNAQ	5
GO:0009199	ribonucleoside triphosphate metabolic process	10/1068	89/18722	0.0300352448884977	0.092827816792512	TMSB4X/TREM2/RHOA/RHOQ/TGFB1/ATP6V1A/LRRK2/IMPDH1/PRKAG2/STAT3	10
GO:0016052	carbohydrate catabolic process	15/1068	154/18722	0.0300689813053823	0.092827816792512	NUPR1/FBP1/HIF1A/P2RX7/DDIT4/AOAH/SCARB2/PRKAG2/ADPGK/STAT3/LDHA/PGK1/PKM/GAA/GM2A	15
GO:0016925	protein sumoylation	7/1068	53/18722	0.0300709829046166	0.092827816792512	ZMIZ1/IFIH1/SUMO3/PIAS1/RANBP2/EGR1/SUMO2	7
GO:0033059	cellular pigmentation	7/1068	53/18722	0.0300709829046166	0.092827816792512	ZEB2/CD63/RAB32/MYO5A/BLOC1S1/RAB29/BLOC1S2	7
GO:0043113	receptor clustering	7/1068	53/18722	0.0300709829046166	0.092827816792512	APOE/CD81/ITGB2/FLNA/ITGA4/ITGAL/GSN	7
GO:0060966	regulation of gene silencing by RNA	7/1068	53/18722	0.0300709829046166	0.092827816792512	ZFP36/NEAT1/TGFB1/NCOR2/STAT3/ADAR/DDX5	7
GO:1990090	cellular response to nerve growth factor stimulus	7/1068	53/18722	0.0300709829046166	0.092827816792512	CIB1/CORO1A/ARPC3/RAP1A/ACAP2/ARF6/UBE3A	7
GO:0030073	insulin secretion	18/1068	195/18722	0.0302459591314941	0.0933145771718365	HLA-DRB1/GLUL/HIF1A/UCP2/ALOX5/TCIRG1/JAK2/CYB5R4/TRPM2/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/STX4/ACSL4/KIF5B	18
GO:0016241	regulation of macroautophagy	14/1068	141/18722	0.0306349373776792	0.094460641194261	NUPR1/HMOX1/ATP6V0B/HIF1A/ATP6V1B2/ATP6V0D1/VPS13C/ATP6V1A/LRRK2/BNIP3L/ATP6V0A1/CAPNS1/SESN3/ATP6V0E1	14
GO:0010939	regulation of necrotic cell death	6/1068	42/18722	0.0307478434452036	0.0946465277982421	NUPR1/TSPO/ASAH1/SLC6A6/ARHGEF2/PPIF	6
GO:0019432	triglyceride biosynthetic process	6/1068	42/18722	0.0307478434452036	0.0946465277982421	C3/LPL/LPGAT1/NR1H3/ACSL1/ACSL4	6
GO:0051602	response to electrical stimulus	6/1068	42/18722	0.0307478434452036	0.0946465277982421	AIF1/SOD2/CD14/BTG2/CYFIP1/NR4A1	6
GO:0046503	glycerolipid catabolic process	8/1068	65/18722	0.0309152297257215	0.0950533217093978	APOC1/SORL1/PLA2G7/GPCPD1/LPL/ABHD2/ABHD12/PLA2G15	8
GO:0070936	protein K48-linked ubiquitination	8/1068	65/18722	0.0309152297257215	0.0950533217093978	IFI27/DTX3L/GABARAP/TNFAIP3/UBE2D1/TTC3/UBE3A/UBE2D3	8
GO:0048017	inositol lipid-mediated signaling	17/1068	182/18722	0.0313002120479479	0.0961822005755847	TREM2/ADAP2/CSF1R/IL18/HCST/ZFP36L1/HGF/KLF4/PIK3AP1/PTAFR/NCF1/PTPN6/JAK2/FGR/HCLS1/UBE3A/PIK3R1	17
GO:0090276	regulation of peptide hormone secretion	18/1068	196/18722	0.0316026323102449	0.0970562344599211	HLA-DRB1/GLUL/HIF1A/UCP2/ALOX5/TCIRG1/JAK2/TRPM2/RAB8B/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/STX4/ACSL4/KIF5B	18
GO:0032409	regulation of transporter activity	26/1068	310/18722	0.0320471174233234	0.0983653274267652	TMSB4X/TREM2/CTSS/SGK1/FXYD5/YWHAH/ACTB/IFNGR2/MEF2C/VMP1/PRNP/PTAFR/KCNE3/NR1H3/ATP1B1/GLRX/PTK2B/DAPK1/CALM3/CAB39/GSTO1/KLHL24/WNK1/KIF5B/ATP1B3/PPIF	26
GO:0032412	regulation of ion transmembrane transporter activity	23/1068	267/18722	0.0323067666258078	0.0991059196775776	TMSB4X/TREM2/CTSS/FXYD5/YWHAH/IFNGR2/MEF2C/VMP1/PRNP/PTAFR/KCNE3/ATP1B1/GLRX/PTK2B/DAPK1/CALM3/CAB39/GSTO1/KLHL24/WNK1/KIF5B/ATP1B3/PPIF	23
GO:0009135	purine nucleoside diphosphate metabolic process	11/1068	103/18722	0.0327959600455645	0.100435301024896	NUPR1/FBP1/HIF1A/P2RX7/DDIT4/PRKAG2/ADPGK/STAT3/LDHA/PGK1/PKM	11
GO:0009179	purine ribonucleoside diphosphate metabolic process	11/1068	103/18722	0.0327959600455645	0.100435301024896	NUPR1/FBP1/HIF1A/P2RX7/DDIT4/PRKAG2/ADPGK/STAT3/LDHA/PGK1/PKM	11
GO:0050773	regulation of dendrite development	11/1068	103/18722	0.0327959600455645	0.100435301024896	YWHAH/ACTR2/RHOA/SDC2/PREX1/CAMK1D/RAP2A/CYFIP1/IQGAP1/ARF6/DBNL	11
GO:0033559	unsaturated fatty acid metabolic process	12/1068	116/18722	0.0329567129095791	0.100813164886672	CD74/FABP5/GPX1/ALOX5/TBXAS1/SCD/PTGS1/GPX4/IL1B/ABHD12/TNFRSF1A/SCP2	12
GO:0035967	cellular response to topologically incorrect protein	12/1068	116/18722	0.0329567129095791	0.100813164886672	TMBIM6/HSPA1A/SERP1/EIF2AK2/ERO1A/UBE2W/PPP1R15A/HERPUD1/BAX/ATF3/PIK3R1/SDF2L1	12
GO:0010001	glial cell differentiation	20/1068	225/18722	0.0330500157696807	0.101041294670367	VIM/TREM2/CD9/C1QA/GRN/CXCR4/C5AR1/ID2/LYN/IFNGR1/RHOA/TLR2/TNFRSF1B/TLR4/TGFB1/CSK/STAT3/LRP1/SKI/PLEC	20
GO:0001764	neuron migration	15/1068	156/18722	0.033203209244271	0.101452161428135	CXCR4/PHACTR1/MEF2C/FLNA/NR4A2/AXL/ZMIZ1/VEGFA/DDIT4/ARHGEF2/STAT3/RAC1/SHTN1/BAX/SDCCAG8	15
GO:0010039	response to iron ion	5/1068	32/18722	0.0334254651336825	0.101785445745683	B2M/C1QA/HAMP/HMOX1/HIF1A	5
GO:0035767	endothelial cell chemotaxis	5/1068	32/18722	0.0334254651336825	0.101785445745683	TMSB4X/LGMN/VEGFA/NR4A1/RAB13	5
GO:0046475	glycerophospholipid catabolic process	5/1068	32/18722	0.0334254651336825	0.101785445745683	APOC1/PLA2G7/GPCPD1/ABHD12/PLA2G15	5
GO:0051497	negative regulation of stress fiber assembly	5/1068	32/18722	0.0334254651336825	0.101785445745683	WAS/ARAP1/PAK2/PIK3R1/PFN1	5
GO:0060323	head morphogenesis	5/1068	32/18722	0.0334254651336825	0.101785445745683	ATP6AP2/MMP2/RRAS/SGPL1/SKI	5
GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	5/1068	32/18722	0.0334254651336825	0.101785445745683	TMBIM6/HSPA1A/LRRK2/GRINA/HERPUD1	5
GO:0014015	positive regulation of gliogenesis	8/1068	66/18722	0.0334894501406535	0.101865317338763	CXCR4/TSPO/ID2/LYN/TLR2/TNFRSF1B/TGFB1/IL1B	8
GO:0046626	regulation of insulin receptor signaling pathway	8/1068	66/18722	0.0334894501406535	0.101865317338763	SORL1/GNAI2/OSBPL8/SOCS3/IL1B/SESN3/PAK1/PIK3R1	8
GO:0035584	calcium-mediated signaling using intracellular calcium source	4/1068	22/18722	0.0338415748965024	0.102302038174525	PTPRC/PRNP/TRPM2/PTPRJ	4
GO:0046628	positive regulation of insulin receptor signaling pathway	4/1068	22/18722	0.0338415748965024	0.102302038174525	SORL1/GNAI2/OSBPL8/PAK1	4
GO:0051220	cytoplasmic sequestering of protein	4/1068	22/18722	0.0338415748965024	0.102302038174525	TMSB4X/FLNA/NFKBIE/NFKBIA	4
GO:0051412	response to corticosterone	4/1068	22/18722	0.0338415748965024	0.102302038174525	FOS/CDKN1A/FOSB/CALM3	4
GO:0060713	labyrinthine layer morphogenesis	4/1068	22/18722	0.0338415748965024	0.102302038174525	GRB2/ZFP36L1/ST14/SOCS3	4
GO:0060965	negative regulation of gene silencing by miRNA	4/1068	22/18722	0.0338415748965024	0.102302038174525	NEAT1/TGFB1/NCOR2/STAT3	4
GO:0072574	hepatocyte proliferation	4/1068	22/18722	0.0338415748965024	0.102302038174525	NOTCH2/RPS6KA1/TNFAIP3/CEBPB	4
GO:0072575	epithelial cell proliferation involved in liver morphogenesis	4/1068	22/18722	0.0338415748965024	0.102302038174525	NOTCH2/RPS6KA1/TNFAIP3/CEBPB	4
GO:0099563	modification of synaptic structure	4/1068	22/18722	0.0338415748965024	0.102302038174525	RHOA/CYFIP1/CDC42/PFN1	4
GO:1900543	negative regulation of purine nucleotide metabolic process	4/1068	22/18722	0.0338415748965024	0.102302038174525	NUPR1/FBP1/DDIT4/STAT3	4
GO:2000114	regulation of establishment of cell polarity	4/1068	22/18722	0.0338415748965024	0.102302038174525	PTK2B/SHTN1/ROCK1/GSN	4
GO:0030010	establishment of cell polarity	14/1068	143/18722	0.0339790338235007	0.102626174389284	MSN/RHOA/DOCK2/TCIRG1/CYTH1/PTK2B/SHTN1/ROCK1/GSN/PAK1/ARF6/CDC42/SDCCAG8/RAB10	14
GO:0009268	response to pH	6/1068	43/18722	0.0340720980282456	0.102626174389284	CTSS/GPR65/LGMN/HVCN1/MCOLN1/CLCN7	6
GO:0032365	intracellular lipid transport	6/1068	43/18722	0.0340720980282456	0.102626174389284	NPC2/ABCG1/CPT1A/ABCA1/ARL8B/SCP2	6
GO:0046636	negative regulation of alpha-beta T cell activation	6/1068	43/18722	0.0340720980282456	0.102626174389284	LGALS9/CD300A/LILRB1/TNFRSF14/RUNX1/BCL6	6
GO:0098927	vesicle-mediated transport between endosomal compartments	6/1068	43/18722	0.0340720980282456	0.102626174389284	SORL1/MSN/FLNA/CORO1A/CHMP3/RAB7A	6
GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	6/1068	43/18722	0.0340720980282456	0.102626174389284	SOD2/HMOX1/MEF2C/RHOA/CDKN1A/GNA13	6
GO:0051146	striated muscle cell differentiation	24/1068	283/18722	0.0342646056037833	0.102626174389284	GPX1/CD9/CD81/HAMP/CD53/MEF2A/PLD3/SLC8A1/PLEKHO1/MEF2C/ARRB2/RB1/YBX1/VEGFA/TGFB1/PRKAR1A/PAK1/SKI/FLII/AKAP13/RGS2/FLOT1/PLEC/BHLHE41	24
GO:0008298	intracellular mRNA localization	3/1068	13/18722	0.034443291664009	0.102626174389284	ZFP36/ZFP36L1/ZNF385A	3
GO:0031392	regulation of prostaglandin biosynthetic process	3/1068	13/18722	0.034443291664009	0.102626174389284	CD74/FABP5/IL1B	3
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	3/1068	13/18722	0.034443291664009	0.102626174389284	CARD16/LILRA2/TNFAIP3	3
GO:0035745	T-helper 2 cell cytokine production	3/1068	13/18722	0.034443291664009	0.102626174389284	CD81/RSAD2/DENND1B	3
GO:0042492	gamma-delta T cell differentiation	3/1068	13/18722	0.034443291664009	0.102626174389284	NCKAP1L/PTPRC/SYK	3
GO:0044794	positive regulation by host of viral process	3/1068	13/18722	0.034443291664009	0.102626174389284	APOE/IGF2R/CFL1	3
GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	3/1068	13/18722	0.034443291664009	0.102626174389284	HBEGF/NCF1/ADAM17	3
GO:0048012	hepatocyte growth factor receptor signaling pathway	3/1068	13/18722	0.034443291664009	0.102626174389284	HGF/RAC1/PAK1	3
GO:0051709	regulation of killing of cells of other organism	3/1068	13/18722	0.034443291664009	0.102626174389284	CLEC7A/SYK/P2RX7	3
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	3/1068	13/18722	0.034443291664009	0.102626174389284	APC/CDC42/RCC2	3
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	3/1068	13/18722	0.034443291664009	0.102626174389284	ZFP36/PABPC1/BTG2	3
GO:0060670	branching involved in labyrinthine layer morphogenesis	3/1068	13/18722	0.034443291664009	0.102626174389284	GRB2/ST14/SOCS3	3
GO:0070486	leukocyte aggregation	3/1068	13/18722	0.034443291664009	0.102626174389284	CD44/MSN/IL1B	3
GO:0110096	cellular response to aldehyde	3/1068	13/18722	0.034443291664009	0.102626174389284	ALDH1A1/RDH11/AKR1A1	3
GO:1900272	negative regulation of long-term synaptic potentiation	3/1068	13/18722	0.034443291664009	0.102626174389284	APOE/TYROBP/PRNP	3
GO:1903977	positive regulation of glial cell migration	3/1068	13/18722	0.034443291664009	0.102626174389284	TREM2/CCL3/LRP1	3
GO:1905244	regulation of modification of synaptic structure	3/1068	13/18722	0.034443291664009	0.102626174389284	RHOA/CYFIP1/CDC42	3
GO:1905907	negative regulation of amyloid fibril formation	3/1068	13/18722	0.034443291664009	0.102626174389284	APOE/TREM2/PFDN5	3
GO:2000551	regulation of T-helper 2 cell cytokine production	3/1068	13/18722	0.034443291664009	0.102626174389284	CD81/RSAD2/DENND1B	3
GO:1902600	proton transmembrane transport	15/1068	157/18722	0.0348566387517374	0.103763165865011	TMSB4X/ATP6V1F/ATP6V0B/SLC15A3/UCP2/ATP6V1B2/ATP6V0D1/TCIRG1/ATP6V1A/HVCN1/ATP6V0A1/ATP6AP1/ATP6V0E1/ATP1A1/PPIF	15
GO:0006892	post-Golgi vesicle-mediated transport	11/1068	104/18722	0.0348633468705086	0.103763165865011	LAPTM5/SORL1/VAMP5/GGA2/VPS13C/MYO5A/CSK/ATP2C1/GGA1/LAMP1/RAB10	11
GO:0048469	cell maturation	16/1068	171/18722	0.0354443245699312	0.10543416503823	C3/C1QA/CLEC7A/HIF1A/RB1/NR4A2/AXL/VEGFA/BTK/ABHD2/KLF2/LRRK2/PTK2B/CDKN1A/CEBPA/PTBP3	16
GO:0044843	cell cycle G1/S phase transition	21/1068	241/18722	0.0355258361087025	0.105615777654487	GPNMB/AIF1/ID2/RB1/EIF4EBP1/KLF4/BID/PTPN6/PLK3/SLFN11/CDKN1A/KMT2E/RPS27L/RGCC/ATM/ADAM17/APC/BACH1/PIAS1/PSME2/APPL1	21
GO:0051279	regulation of release of sequestered calcium ion into cytosol	9/1068	79/18722	0.0355445241327924	0.105615777654487	CYBA/SLC8A1/LYN/CORO1A/PTPN6/PTK2B/CALM3/GSTO1/BAX	9
GO:0014065	phosphatidylinositol 3-kinase signaling	14/1068	144/18722	0.0357465697044299	0.106099279496757	TREM2/IL18/HCST/ZFP36L1/HGF/KLF4/PIK3AP1/NCF1/PTPN6/JAK2/FGR/HCLS1/UBE3A/PIK3R1	14
GO:0033135	regulation of peptidyl-serine phosphorylation	14/1068	144/18722	0.0357465697044299	0.106099279496757	CD44/ARRB2/HGF/VEGFA/TGFB1/DDIT4/CREBL2/RASSF2/STK4/FNIP2/PAK1/HCLS1/FNIP1/BAX	14
GO:0002040	sprouting angiogenesis	17/1068	185/18722	0.0357927552370157	0.106177958910905	GLUL/HMOX1/RNF213/RHOA/CIB1/ALOX5/JAK1/KLF4/VEGFA/KLF2/SPRED1/ITGA5/PTK2B/VEGFB/NR4A1/PKM/CDC42	17
GO:0045620	negative regulation of lymphocyte differentiation	7/1068	55/18722	0.0359279501756978	0.106520450081355	CD74/ID2/LILRB4/FGL2/RUNX1/BCL6/IRF1	7
GO:0016311	dephosphorylation	33/1068	417/18722	0.0360880716570159	0.10693642760091	ACP5/PLEK/FBP1/DUSP1/LGALS3/MEF2C/NCKAP1L/PTPRC/GNAI2/CD300A/NCEH1/TGFB1/DUSP23/LILRB2/PTPN6/JAK2/PPM1M/INPP5D/CD33/LRRK2/PTPN18/PTPRJ/DAPP1/MTMR6/PTP4A2/ACP2/DUSP3/CALM3/ROCK1/PPP1R15A/PPP2R3C/BOD1L1/ATP1A1	33
GO:0002790	peptide secretion	21/1068	242/18722	0.0369004235487416	0.109212630045723	HLA-DRB1/CD74/GLUL/HIF1A/UCP2/ALOX5/TCIRG1/JAK2/CYB5R4/TRPM2/RAB8B/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/ABCA1/STX4/ACSL4/KIF5B	21
GO:1903320	regulation of protein modification by small protein conjugation or removal	21/1068	242/18722	0.0369004235487416	0.109212630045723	LAPTM5/TSPO/ISG15/HIF1A/ARRB2/HSPA1A/ZMIZ1/DTX3L/LRRK2/GABARAP/TNFAIP3/TGFBR1/UBE2D1/IVNS1ABP/SVBP/HERPUD1/UBE3A/XIAP/PIAS1/EGR1/CAMLG	21
GO:0045446	endothelial cell differentiation	12/1068	118/18722	0.0369169453675682	0.109212630045723	GPX1/CXCR4/MSN/PECAM1/RAP1A/VEGFA/MYADM/MYD88/IL1B/BTG1/TNFRSF1A/ROCK1	12
GO:0000041	transition metal ion transport	11/1068	105/18722	0.0370208103200962	0.109459886294378	FTL/B2M/FTH1/HAMP/SLC11A1/TRPM2/ATP2C1/SLC31A1/MCOLN1/SLC30A1/ATOX1	11
GO:0042770	signal transduction in response to DNA damage	16/1068	172/18722	0.0370994438394115	0.109572303753401	CD74/CD44/GRB2/TAOK3/SP100/BID/PLK3/SPRED1/CDKN1A/RNASEH2B/RPS27L/ATM/DDX5/FOXN3/ZNF385A/TAOK1	16
GO:1990138	neuron projection extension	16/1068	172/18722	0.0370994438394115	0.109572303753401	APOE/CXCR4/ALCAM/DPYSL2/TWF2/VEGFA/ITGA4/ARHGAP4/ITSN2/CYFIP1/SHTN1/LRP1/IQGAP1/RTN4/PAK1/DBNL	16
GO:0010259	multicellular organism aging	5/1068	33/18722	0.0376089540500835	0.110444448584535	INPP5D/LRRK2/ERCC1/SERP1/CISD2	5
GO:0010737	protein kinase A signaling	5/1068	33/18722	0.0376089540500835	0.110444448584535	LCP1/LRRK2/PRKACB/PJA2/RAB13	5
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	5/1068	33/18722	0.0376089540500835	0.110444448584535	LYN/TGFB1/FGR/PTK2B/CDC42	5
GO:0046685	response to arsenic-containing substance	5/1068	33/18722	0.0376089540500835	0.110444448584535	HMOX1/CDKN1A/GSTO1/ATF3/PPIF	5
GO:0050901	leukocyte tethering or rolling	5/1068	33/18722	0.0376089540500835	0.110444448584535	PTAFR/SELPLG/ITGA4/SPN/ROCK1	5
GO:0032007	negative regulation of TOR signaling	6/1068	44/18722	0.0376198844511443	0.110444448584535	HIF1A/DDIT4/TMEM127/SESN3/ATM/FNIP1	6
GO:0032620	interleukin-17 production	6/1068	44/18722	0.0376198844511443	0.110444448584535	IL18/NCKAP1L/TLR4/PRNP/TGFB1/MYD88	6
GO:0032660	regulation of interleukin-17 production	6/1068	44/18722	0.0376198844511443	0.110444448584535	IL18/NCKAP1L/TLR4/PRNP/TGFB1/MYD88	6
GO:0046006	regulation of activated T cell proliferation	6/1068	44/18722	0.0376198844511443	0.110444448584535	PYCARD/IL18/LGALS9/LILRB4/PRNP/PRKAR1A	6
GO:0050999	regulation of nitric-oxide synthase activity	6/1068	44/18722	0.0376198844511443	0.110444448584535	APOE/HIF1A/DDAH2/PTK2B/IL1B/CALM3	6
GO:0060711	labyrinthine layer development	6/1068	44/18722	0.0376198844511443	0.110444448584535	GRB2/JUNB/ZFP36L1/ST14/VASH1/SOCS3	6
GO:0001649	osteoblast differentiation	20/1068	229/18722	0.0386820057760643	0.113500871760545	SPP1/GPNMB/CCL3/JUNB/MEF2C/HGF/CLEC5A/TCIRG1/PDLIM7/RASSF2/IL6R/ATP6AP1/CEBPB/ADAR/DDX5/CEBPA/SKI/CLIC1/BCAP29/HSD17B4	20
GO:0090398	cellular senescence	10/1068	93/18722	0.0390335126688526	0.113892339504129	B2M/SPI1/ID2/YBX1/ABI3/VASH1/NAMPT/BCL6/CDKN1A/ATM	10
GO:0097306	cellular response to alcohol	10/1068	93/18722	0.0390335126688526	0.113892339504129	SOD2/SPI1/CYBB/AHR/PTGER4/KLF4/KLF2/ADCY7/ABCA1/GNB1	10
GO:0010812	negative regulation of cell-substrate adhesion	8/1068	68/18722	0.0390660280855204	0.113892339504129	LGALS1/GBP1/RHOA/CORO1C/BCL6/LRP1/RCC2/PIK3R1	8
GO:0034394	protein localization to cell surface	8/1068	68/18722	0.0390660280855204	0.113892339504129	TYROBP/FLNA/GGA2/KCNAB2/GGA1/STX4/PICALM/ARF6	8
GO:1902305	regulation of sodium ion transmembrane transport	8/1068	68/18722	0.0390660280855204	0.113892339504129	FXYD5/YWHAH/ATP1B1/GLRX/KLHL24/WNK1/KIF5B/ATP1B3	8
GO:0010332	response to gamma radiation	7/1068	56/18722	0.0391200389305177	0.113892339504129	GPX1/CYBA/PTPRC/CDKN1A/ATM/BAX/EGR1	7
GO:0043388	positive regulation of DNA binding	7/1068	56/18722	0.0391200389305177	0.113892339504129	PLAUR/RB1/KLF4/TGFB1/JAK2/CALM3/SKI	7
GO:0048008	platelet-derived growth factor receptor signaling pathway	7/1068	56/18722	0.0391200389305177	0.113892339504129	TXNIP/VEGFA/JAK2/PTPRJ/SGPL1/LRP1/ZFAND5	7
GO:1990089	response to nerve growth factor	7/1068	56/18722	0.0391200389305177	0.113892339504129	CIB1/CORO1A/ARPC3/RAP1A/ACAP2/ARF6/UBE3A	7
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	4/1068	23/18722	0.0391742368642818	0.113892339504129	CYBA/CTSZ/RHOA/ATP6AP2	4
GO:0009162	deoxyribonucleoside monophosphate metabolic process	4/1068	23/18722	0.0391742368642818	0.113892339504129	TYMP/UPP1/DPYD/TK2	4
GO:0035994	response to muscle stretch	4/1068	23/18722	0.0391742368642818	0.113892339504129	FOS/SLC8A1/NFKBIA/GSN	4
GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	4/1068	23/18722	0.0391742368642818	0.113892339504129	IL6R/SPN/STAT6/STAT3	4
GO:0045723	positive regulation of fatty acid biosynthetic process	4/1068	23/18722	0.0391742368642818	0.113892339504129	CD74/LPGAT1/NR1H3/IL1B	4
GO:0045980	negative regulation of nucleotide metabolic process	4/1068	23/18722	0.0391742368642818	0.113892339504129	NUPR1/FBP1/DDIT4/STAT3	4
GO:0051882	mitochondrial depolarization	4/1068	23/18722	0.0391742368642818	0.113892339504129	TSPO/CASP1/LRRK2/PPP2R3C	4
GO:0072576	liver morphogenesis	4/1068	23/18722	0.0391742368642818	0.113892339504129	NOTCH2/RPS6KA1/TNFAIP3/CEBPB	4
GO:0009185	ribonucleoside diphosphate metabolic process	11/1068	106/18722	0.0392699889759087	0.114109240987616	NUPR1/FBP1/HIF1A/P2RX7/DDIT4/PRKAG2/ADPGK/STAT3/LDHA/PGK1/PKM	11
GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process	13/1068	133/18722	0.0404565003037254	0.117493689794888	LAPTM5/TREM2/NUPR1/CTSC/HSPA1A/PLK3/LRRK2/PTK2B/GABARAP/CEBPA/HERPUD1/PIAS1/SUMO2	13
GO:0051817	modulation of process of other organism involved in symbiotic interaction	9/1068	81/18722	0.0407940584111158	0.118346633971173	APOE/IFI27/CCL3/JUN/CD4/CCL4/SAP30/IGF2R/CFL1	9
GO:1903533	regulation of protein targeting	9/1068	81/18722	0.0407940584111158	0.118346633971173	ITGB2/CIB1/PRNP/ITGAM/LRRK2/BNIP3L/NUCB1/PAK1/UBE2D3	9
GO:0048675	axon extension	12/1068	120/18722	0.0412019925989348	0.118934352377848	APOE/ALCAM/DPYSL2/TWF2/VEGFA/ARHGAP4/CYFIP1/SHTN1/LRP1/RTN4/PAK1/DBNL	12
GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	6/1068	45/18722	0.0413949323582317	0.118934352377848	GPX1/TREM2/SOD2/HIF1A/JAK2/MCL1	6
GO:0035305	negative regulation of dephosphorylation	6/1068	45/18722	0.0413949323582317	0.118934352377848	LGALS3/NCKAP1L/GNAI2/ROCK1/PPP1R15A/BOD1L1	6
GO:2000273	positive regulation of signaling receptor activity	6/1068	45/18722	0.0413949323582317	0.118934352377848	IFNGR2/HIF1A/HBEGF/NCF1/JAK2/ADAM17	6
GO:0001889	liver development	14/1068	147/18722	0.0414445770285434	0.118934352377848	HAMP/HMOX1/HGF/UCP2/RAP1A/NOTCH2/RPS6KA1/TNFAIP3/ACAT1/CPT1A/CEBPB/IGF2R/CEBPA/ARF6	14
GO:1902414	protein localization to cell junction	10/1068	94/18722	0.0415444895460391	0.118934352377848	ACTB/PECAM1/FLNA/RAP1A/JAK1/PAK2/ADAM10/LAMTOR2/RAB8A/KIF5B	10
GO:0051341	regulation of oxidoreductase activity	11/1068	107/18722	0.0416124479548815	0.118934352377848	APOE/CYBA/HIF1A/GNAI2/DDAH2/LRRK2/PTK2B/IL1B/CALM3/HM13/OXA1L	11
GO:0002475	antigen processing and presentation via MHC class Ib	3/1068	14/18722	0.0420236301741442	0.118934352377848	B2M/HLA-E/HLA-F	3
GO:0002756	MyD88-independent toll-like receptor signaling pathway	3/1068	14/18722	0.0420236301741442	0.118934352377848	TLR4/IRF7/CD300LF	3
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	3/1068	14/18722	0.0420236301741442	0.118934352377848	C3/HLA-E/BTK	3
GO:0006465	signal peptide processing	3/1068	14/18722	0.0420236301741442	0.118934352377848	SPCS3/HM13/SEC11A	3
GO:0009158	ribonucleoside monophosphate catabolic process	3/1068	14/18722	0.0420236301741442	0.118934352377848	UPP1/DPYD/HPRT1	3
GO:0009159	deoxyribonucleoside monophosphate catabolic process	3/1068	14/18722	0.0420236301741442	0.118934352377848	TYMP/UPP1/DPYD	3
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	3/1068	14/18722	0.0420236301741442	0.118934352377848	GBP1/CORO1C/RCC2	3
GO:0010872	regulation of cholesterol esterification	3/1068	14/18722	0.0420236301741442	0.118934352377848	APOE/APOC1/ABCG1	3
GO:0030007	cellular potassium ion homeostasis	3/1068	14/18722	0.0420236301741442	0.118934352377848	ATP1B1/ATP1B3/ATP1A1	3
GO:0035641	locomotory exploration behavior	3/1068	14/18722	0.0420236301741442	0.118934352377848	APOE/LRRK2/UBE3A	3
GO:0036295	cellular response to increased oxygen levels	3/1068	14/18722	0.0420236301741442	0.118934352377848	ATP6V0D1/ATP6V1A/ATP6AP1	3
GO:0043455	regulation of secondary metabolic process	3/1068	14/18722	0.0420236301741442	0.118934352377848	ZEB2/MFSD12/APPL1	3
GO:0043558	regulation of translational initiation in response to stress	3/1068	14/18722	0.0420236301741442	0.118934352377848	EIF2AK2/PPP1R15A/DNAJC3	3
GO:0043922	negative regulation by host of viral transcription	3/1068	14/18722	0.0420236301741442	0.118934352377848	CCL3/JUN/CCL4	3
GO:0045059	positive thymic T cell selection	3/1068	14/18722	0.0420236301741442	0.118934352377848	CD74/PTPRC/DOCK2	3
GO:0045989	positive regulation of striated muscle contraction	3/1068	14/18722	0.0420236301741442	0.118934352377848	GSTO1/RGS2/ATP1A1	3
GO:0046131	pyrimidine ribonucleoside metabolic process	3/1068	14/18722	0.0420236301741442	0.118934352377848	UPP1/APOBEC3C/APOBEC3A	3
GO:0046133	pyrimidine ribonucleoside catabolic process	3/1068	14/18722	0.0420236301741442	0.118934352377848	UPP1/APOBEC3C/APOBEC3A	3
GO:0046479	glycosphingolipid catabolic process	3/1068	14/18722	0.0420236301741442	0.118934352377848	GALC/HEXA/GM2A	3
GO:0048021	regulation of melanin biosynthetic process	3/1068	14/18722	0.0420236301741442	0.118934352377848	ZEB2/MFSD12/APPL1	3
GO:0048875	chemical homeostasis within a tissue	3/1068	14/18722	0.0420236301741442	0.118934352377848	CTSH/OAS1/VEGFA	3
GO:0051547	regulation of keratinocyte migration	3/1068	14/18722	0.0420236301741442	0.118934352377848	HBEGF/ADAM9/ARF6	3
GO:0055057	neuroblast division	3/1068	14/18722	0.0420236301741442	0.118934352377848	ARHGEF2/NUMB/RAB10	3
GO:0060081	membrane hyperpolarization	3/1068	14/18722	0.0420236301741442	0.118934352377848	SOD2/CASP1/ATP1A1	3
GO:0060576	intestinal epithelial cell development	3/1068	14/18722	0.0420236301741442	0.118934352377848	HIF1A/PRDM1/CDKN1A	3
GO:0061043	regulation of vascular wound healing	3/1068	14/18722	0.0420236301741442	0.118934352377848	CXCR4/ALOX5/TNFAIP3	3
GO:0071236	cellular response to antibiotic	3/1068	14/18722	0.0420236301741442	0.118934352377848	MEF2C/ACTR2/CRIP1	3
GO:0086103	G protein-coupled receptor signaling pathway involved in heart process	3/1068	14/18722	0.0420236301741442	0.118934352377848	GNAI2/AKAP13/RGS2	3
GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	3/1068	14/18722	0.0420236301741442	0.118934352377848	GBP1/CORO1C/RCC2	3
GO:1900376	regulation of secondary metabolite biosynthetic process	3/1068	14/18722	0.0420236301741442	0.118934352377848	ZEB2/MFSD12/APPL1	3
GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	3/1068	14/18722	0.0420236301741442	0.118934352377848	CD74/CD44/ZNF385A	3
GO:1902916	positive regulation of protein polyubiquitination	3/1068	14/18722	0.0420236301741442	0.118934352377848	GABARAP/UBE2D1/XIAP	3
GO:2001171	positive regulation of ATP biosynthetic process	3/1068	14/18722	0.0420236301741442	0.118934352377848	TMSB4X/TREM2/STAT3	3
GO:2001256	regulation of store-operated calcium entry	3/1068	14/18722	0.0420236301741442	0.118934352377848	CD84/HOMER3/SARAF	3
GO:0045669	positive regulation of osteoblast differentiation	8/1068	69/18722	0.04207364374466	0.118934352377848	MEF2C/HGF/PDLIM7/IL6R/ATP6AP1/CEBPB/CEBPA/CLIC1	8
GO:0060193	positive regulation of lipase activity	8/1068	69/18722	0.04207364374466	0.118934352377848	C5AR1/CD86/RHOA/PTAFR/NR1H3/GNA15/GNA13/GNAQ	8
GO:0007095	mitotic G2 DNA damage checkpoint signaling	5/1068	34/18722	0.0420987051596906	0.118934352377848	TAOK3/CDKN1A/ATM/FOXN3/TAOK1	5
GO:0032770	positive regulation of monooxygenase activity	5/1068	34/18722	0.0420987051596906	0.118934352377848	APOE/HIF1A/PTK2B/IL1B/CALM3	5
GO:0035590	purinergic nucleotide receptor signaling pathway	5/1068	34/18722	0.0420987051596906	0.118934352377848	GPR34/GNAI2/P2RX7/PTAFR/ADORA3	5
GO:0050931	pigment cell differentiation	5/1068	34/18722	0.0420987051596906	0.118934352377848	ZEB2/CD63/RAB32/MEF2C/MITF	5
GO:0051085	chaperone cofactor-dependent protein refolding	5/1068	34/18722	0.0420987051596906	0.118934352377848	CD74/HSPA1A/ERO1A/HSPH1/SDF2L1	5
GO:0070232	regulation of T cell apoptotic process	5/1068	34/18722	0.0420987051596906	0.118934352377848	LGALS3/LGALS9/HIF1A/ADAM8/TSC22D3	5
GO:0090075	relaxation of muscle	5/1068	34/18722	0.0420987051596906	0.118934352377848	SLC8A1/ATP1B1/GSN/RGS2/ATP1A1	5
GO:0030219	megakaryocyte differentiation	7/1068	57/18722	0.0424919627080831	0.119982538342657	MEF2C/CIB1/PTPN6/SH2B3/FLI1/ABI1/ZNF385A	7
GO:0062012	regulation of small molecule metabolic process	27/1068	334/18722	0.043384084211302	0.12243750962562	APOE/APOC1/CD74/FABP5/TMSB4X/TREM2/NUPR1/PLEK/FBP1/SLC7A7/HIF1A/PDK4/P2RX7/DDIT4/PTAFR/NCOR2/LPGAT1/NR1H3/PRKAG2/PTK2B/LACC1/IL1B/STAT3/ABCG1/CPT1A/RANBP2/EGR1	27
GO:0044772	mitotic cell cycle phase transition	33/1068	424/18722	0.0438406037073263	0.123661211502735	GPNMB/AIF1/ZFP36L2/DUSP1/ID2/ZFP36L1/RB1/TAOK3/EIF4EBP1/KLF4/BID/PTPN6/PLK3/SLFN11/CDKN1A/KMT2E/RNASEH2B/RPS27L/RGCC/ATM/FBXL15/CALM3/FOXN3/ADAM17/APC/BACH1/DYNC1LI1/TAOK1/CCNI/RCC2/PIAS1/PSME2/APPL1	33
GO:0036473	cell death in response to oxidative stress	10/1068	95/18722	0.0441636202606015	0.124507259627067	GPX1/TREM2/SOD2/HIF1A/HGF/TLR4/JAK2/TRPM2/LRRK2/MCL1	10
GO:0002922	positive regulation of humoral immune response	4/1068	24/18722	0.0449578465691889	0.126153166972097	TREM2/C3/PTPRC/IL1B	4
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	4/1068	24/18722	0.0449578465691889	0.126153166972097	TYMP/UPP1/DPYD/MBD4	4
GO:0030859	polarized epithelial cell differentiation	4/1068	24/18722	0.0449578465691889	0.126153166972097	MSN/RHOA/CDC42/RAB10	4
GO:0031639	plasminogen activation	4/1068	24/18722	0.0449578465691889	0.126153166972097	CTSZ/PLAU/RUNX1/PGK1	4
GO:0038095	Fc-epsilon receptor signaling pathway	4/1068	24/18722	0.0449578465691889	0.126153166972097	FCER1G/LYN/SYK/BTK	4
GO:0051000	positive regulation of nitric-oxide synthase activity	4/1068	24/18722	0.0449578465691889	0.126153166972097	APOE/HIF1A/PTK2B/CALM3	4
GO:0060561	apoptotic process involved in morphogenesis	4/1068	24/18722	0.0449578465691889	0.126153166972097	SPI1/TNFRSF1B/TNFRSF1A/BAX	4
GO:1903428	positive regulation of reactive oxygen species biosynthetic process	4/1068	24/18722	0.0449578465691889	0.126153166972097	CYBA/SOD2/CD36/TLR4	4
GO:2000310	regulation of NMDA receptor activity	4/1068	24/18722	0.0449578465691889	0.126153166972097	IFNGR2/MEF2C/PTK2B/DAPK1	4
GO:0016236	macroautophagy	24/1068	291/18722	0.0449955757571272	0.126193413090155	NUPR1/HMOX1/ATP6V0B/HIF1A/VMP1/LAMP2/ATP6V1B2/ATP6V0D1/VPS13C/TCIRG1/ATP6V1A/LRRK2/BNIP3L/GABARAP/MCOLN1/ATP6V0A1/CAPNS1/SESN3/STX12/ARL8B/ATG3/ATP6V0E1/CHMP3/RAB7A	24
GO:0001974	blood vessel remodeling	6/1068	46/18722	0.0454003750146413	0.127064535051351	CST3/MEF2C/FLNA/AXL/TGFB1/BAX	6
GO:0034198	cellular response to amino acid starvation	6/1068	46/18722	0.0454003750146413	0.127064535051351	UCP2/RRAGD/CDKN1A/EIF2AK2/SESN3/ATF3	6
GO:0043462	regulation of ATPase activity	6/1068	46/18722	0.0454003750146413	0.127064535051351	ATP1B1/VMA21/OXA1L/ATP1B3/PFN1/PPIF	6
GO:0072599	establishment of protein localization to endoplasmic reticulum	6/1068	46/18722	0.0454003750146413	0.127064535051351	SSR3/SPCS3/MAN1A1/TRAM1/HERPUD1/RAB10	6
GO:1905039	carboxylic acid transmembrane transport	14/1068	149/18722	0.0455832894340713	0.127510331667314	SLC7A7/CD36/SLC16A3/SLC38A6/AQP9/LRRC8C/MPC1/SLC6A6/SFXN3/ACSL1/MFSD12/CPT1A/SLC1A3/RGS2	14
GO:0010043	response to zinc ion	7/1068	58/18722	0.0460463585651449	0.128477884406862	HAMP/TSPO/SOD2/CRIP1/HVCN1/MT1X/SLC30A1	7
GO:0010574	regulation of vascular endothelial growth factor production	7/1068	58/18722	0.0460463585651449	0.128477884406862	C3/C5AR1/C3AR1/HIF1A/TGFB1/HPSE/IL1B	7
GO:0018208	peptidyl-proline modification	7/1068	58/18722	0.0460463585651449	0.128477884406862	FKBP15/FKBP5/P4HA1/CRTAP/ERO1A/RANBP2/PPIF	7
GO:2000649	regulation of sodium ion transmembrane transporter activity	7/1068	58/18722	0.0460463585651449	0.128477884406862	FXYD5/YWHAH/ATP1B1/GLRX/KLHL24/WNK1/KIF5B	7
GO:0061025	membrane fusion	15/1068	163/18722	0.0460482261754766	0.128477884406862	CD9/CORO1A/SAMD9/STX10/STX6/RAB8B/STX4/STX12/ARL8B/STX7/CHMP3/RAB8A/KIF5B/RAB7A/RAB13	15
GO:0071466	cellular response to xenobiotic stimulus	16/1068	177/18722	0.0462215170428476	0.128894731763931	CXCR4/FBP1/MEF2C/RB1/NCEH1/AHR/RAP1A/PRNP/APOBEC3A/RNF149/ACSL1/RAP2A/VKORC1/IL1B/ABCA1/GSTO1	16
GO:0031397	negative regulation of protein ubiquitination	9/1068	83/18722	0.0465436563965172	0.129659044871248	TSPO/ISG15/ARRB2/HSPA1A/DTX3L/TNFAIP3/IVNS1ABP/SVBP/CAMLG	9
GO:1901292	nucleoside phosphate catabolic process	9/1068	83/18722	0.0465436563965172	0.129659044871248	TYMP/SAMHD1/UPP1/NUDT3/DPYD/ENTPD1/HPRT1/MBD4/ACAT1	9
GO:0030510	regulation of BMP signaling pathway	10/1068	96/18722	0.0468925129375195	0.130107839319713	SORL1/SKIL/ENG/NOTCH2/FBXL15/HTRA1/UBE2D1/SKI/XIAP/UBE2D3	10
GO:0034620	cellular response to unfolded protein	10/1068	96/18722	0.0468925129375195	0.130107839319713	TMBIM6/HSPA1A/SERP1/EIF2AK2/ERO1A/PPP1R15A/HERPUD1/BAX/ATF3/PIK3R1	10
GO:0042632	cholesterol homeostasis	10/1068	96/18722	0.0468925129375195	0.130107839319713	APOE/NPC2/IL18/SOAT1/LPL/NR1H3/ABCG1/ABCA1/COMMD9/CNBP	10
GO:1904035	regulation of epithelial cell apoptotic process	10/1068	96/18722	0.0468925129375195	0.130107839319713	NUPR1/ZFP36/HMOX1/ZFP36L1/ARRB2/JAK2/ITGA4/TNFAIP3/RGCC/GSN	10
GO:0001569	branching involved in blood vessel morphogenesis	5/1068	35/18722	0.0468976552032695	0.130107839319713	VEGFA/PLXND1/ENG/TGFBR2/STK4	5
GO:0010765	positive regulation of sodium ion transport	5/1068	35/18722	0.0468976552032695	0.130107839319713	ATP1B1/GLRX/WNK1/KIF5B/ATP1B3	5
GO:0032232	negative regulation of actin filament bundle assembly	5/1068	35/18722	0.0468976552032695	0.130107839319713	WAS/ARAP1/PAK2/PIK3R1/PFN1	5
GO:0039694	viral RNA genome replication	5/1068	35/18722	0.0468976552032695	0.130107839319713	APOBEC3C/APOBEC3A/RAB29/CDC42/PCBP2	5
GO:0043624	cellular protein complex disassembly	13/1068	136/18722	0.0470184343387272	0.130308922286478	CAPG/PLEK/TWF2/CIB1/ARHGEF2/CAPZA2/CAPZA1/APC/GSN/FLII/CFL1/TAOK1/CAPZB	13
GO:1900180	regulation of protein localization to nucleus	13/1068	136/18722	0.0470184343387272	0.130308922286478	GLUL/LILRB4/CD36/FLNA/PARP9/TGFB1/MDFIC/DTX3L/JAK2/SUMO3/NUP62/HCLS1/PIK3R1	13
GO:0045926	negative regulation of growth	21/1068	249/18722	0.0476435663862319	0.13197365719718	SPP1/BST2/FBP1/LGMN/PPT1/HIF1A/RB1/HSPA1A/TGFB1/TGFBR2/NOTCH2/BCL6/ARHGAP4/MT1X/STK4/CDKN1A/PTPRJ/BTG1/RTN4/PAK1/RGS2	21
GO:0061008	hepaticobiliary system development	14/1068	150/18722	0.047757628082733	0.132153928786886	HAMP/HMOX1/HGF/UCP2/RAP1A/NOTCH2/RPS6KA1/TNFAIP3/ACAT1/CPT1A/CEBPB/IGF2R/CEBPA/ARF6	14
GO:1903825	organic acid transmembrane transport	14/1068	150/18722	0.047757628082733	0.132153928786886	SLC7A7/CD36/SLC16A3/SLC38A6/AQP9/LRRC8C/MPC1/SLC6A6/SFXN3/ACSL1/MFSD12/CPT1A/SLC1A3/RGS2	14
GO:0048015	phosphatidylinositol-mediated signaling	16/1068	178/18722	0.048220956281938	0.133367647410219	TREM2/CSF1R/IL18/HCST/ZFP36L1/HGF/KLF4/PIK3AP1/PTAFR/NCF1/PTPN6/JAK2/FGR/HCLS1/UBE3A/PIK3R1	16
GO:0000281	mitotic cytokinesis	8/1068	71/18722	0.0485390191716302	0.1341098553252	RHOA/KLHDC8B/ROCK1/APC/NUP62/RHOB/CHMP3/CHMP1B	8
GO:0071230	cellular response to amino acid stimulus	8/1068	71/18722	0.0485390191716302	0.1341098553252	CYBA/CYBB/RRAGD/MMP2/LAMTOR4/CEBPB/SESN3/LAMTOR2	8
GO:1903050	regulation of proteolysis involved in cellular protein catabolic process	19/1068	221/18722	0.0490775046700763	0.135528257522892	APOE/LAPTM5/GPX1/TREM2/NUPR1/CTSC/SDCBP/HSPA1A/PLK3/LRRK2/PTK2B/GABARAP/CEBPA/HERPUD1/UBE3A/PIAS1/PSME2/CAMLG/SUMO2	19
GO:0034754	cellular hormone metabolic process	13/1068	137/18722	0.0493606548991998	0.136240457205157	SPP1/TSPO/ALDH1A1/SCPEP1/IL4I1/HSD17B11/SRD5A3/RDH11/SGPL1/DHRS3/DHRS4/EGR1/HSD17B4	13
GO:0042440	pigment metabolic process	9/1068	84/18722	0.0496105916196248	0.136449646006028	TSPO/ZEB2/HMOX1/SLCO2B1/BLVRB/MFSD12/HPRT1/BLVRA/APPL1	9
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	9/1068	84/18722	0.0496105916196248	0.136449646006028	GPNMB/RB1/KLF4/PLK3/SLFN11/CDKN1A/RPS27L/ATM/APC	9
GO:0007595	lactation	6/1068	47/18722	0.0496387426074562	0.136449646006028	HIF1A/USF2/OAS2/VEGFA/NCOR2/STAT5A	6
GO:0010799	regulation of peptidyl-threonine phosphorylation	6/1068	47/18722	0.0496387426074562	0.136449646006028	TGFB1/DDIT4/SPRED1/PRKAG2/CALM3/CAB39	6
GO:0031641	regulation of myelination	6/1068	47/18722	0.0496387426074562	0.136449646006028	TYMP/CTSC/HGF/ITGAX/TNFRSF1B/CYFIP1	6
GO:0045581	negative regulation of T cell differentiation	6/1068	47/18722	0.0496387426074562	0.136449646006028	CD74/LILRB4/FGL2/RUNX1/BCL6/IRF1	6
GO:0050798	activated T cell proliferation	6/1068	47/18722	0.0496387426074562	0.136449646006028	PYCARD/IL18/LGALS9/LILRB4/PRNP/PRKAR1A	6
GO:0120163	negative regulation of cold-induced thermogenesis	6/1068	47/18722	0.0496387426074562	0.136449646006028	ALDH1A1/RB1/TLR4/NR1H3/ADAM17/TLE3	6
GO:0010596	negative regulation of endothelial cell migration	10/1068	97/18722	0.0497326621718843	0.136564644143067	APOE/MEF2C/RHOA/KLF4/SP100/TGFB1/VASH1/SPRED1/RGCC/SVBP	10
GO:0055092	sterol homeostasis	10/1068	97/18722	0.0497326621718843	0.136564644143067	APOE/NPC2/IL18/SOAT1/LPL/NR1H3/ABCG1/ABCA1/COMMD9/CNBP	10
GO:0032768	regulation of monooxygenase activity	7/1068	59/18722	0.0497855044277761	0.136564644143067	APOE/HIF1A/DDAH2/PTK2B/IL1B/CALM3/HM13	7
GO:0051353	positive regulation of oxidoreductase activity	7/1068	59/18722	0.0497855044277761	0.136564644143067	APOE/CYBA/HIF1A/GNAI2/PTK2B/IL1B/CALM3	7
GO:0046395	carboxylic acid catabolic process	20/1068	236/18722	0.0501823717211036	0.136564644143067	GLUL/SDS/HNMT/IL4I1/DDAH2/SDSL/KYNU/GNPDA1/ACAA2/GLS/ABHD2/AKR1A1/ACAT1/CPT1A/FAH/NPL/NAGK/PLA2G15/SCP2/HSD17B4	20
GO:0006878	cellular copper ion homeostasis	3/1068	15/18722	0.0503639069393446	0.136564644143067	PRNP/SLC31A1/SCO2	3
GO:0010713	negative regulation of collagen metabolic process	3/1068	15/18722	0.0503639069393446	0.136564644143067	CST3/RAP1A/CIITA	3
GO:0010763	positive regulation of fibroblast migration	3/1068	15/18722	0.0503639069393446	0.136564644143067	SLC8A1/TGFB1/PAK1	3
GO:0010820	positive regulation of T cell chemotaxis	3/1068	15/18722	0.0503639069393446	0.136564644143067	ADAM17/ADAM10/WNK1	3
GO:0019511	peptidyl-proline hydroxylation	3/1068	15/18722	0.0503639069393446	0.136564644143067	P4HA1/CRTAP/ERO1A	3
GO:0031958	corticosteroid receptor signaling pathway	3/1068	15/18722	0.0503639069393446	0.136564644143067	YWHAH/JAK2/NR3C1	3
GO:0032897	negative regulation of viral transcription	3/1068	15/18722	0.0503639069393446	0.136564644143067	ZFP36/IFITM3/TRIM14	3
GO:0033599	regulation of mammary gland epithelial cell proliferation	3/1068	15/18722	0.0503639069393446	0.136564644143067	GPX1/RTN4/BAX	3
GO:0034380	high-density lipoprotein particle assembly	3/1068	15/18722	0.0503639069393446	0.136564644143067	APOE/ABCA1/PRKACB	3
GO:0034638	phosphatidylcholine catabolic process	3/1068	15/18722	0.0503639069393446	0.136564644143067	APOC1/PLA2G7/PLA2G15	3
GO:0042994	cytoplasmic sequestering of transcription factor	3/1068	15/18722	0.0503639069393446	0.136564644143067	TMSB4X/NFKBIE/NFKBIA	3
GO:0045064	T-helper 2 cell differentiation	3/1068	15/18722	0.0503639069393446	0.136564644143067	CD86/IL18/BCL6	3
GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening	3/1068	15/18722	0.0503639069393446	0.136564644143067	ZFP36/PABPC1/BTG2	3
GO:0070071	proton-transporting two-sector ATPase complex assembly	3/1068	15/18722	0.0503639069393446	0.136564644143067	VMA21/OXA1L/TMEM70	3
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	3/1068	15/18722	0.0503639069393446	0.136564644143067	CD81/SORL1/TMEM30A	3
GO:0071474	cellular hyperosmotic response	3/1068	15/18722	0.0503639069393446	0.136564644143067	RCSD1/ARHGEF2/MICU1	3
GO:0098760	response to interleukin-7	3/1068	15/18722	0.0503639069393446	0.136564644143067	LSP1/YBX1/BTK	3
GO:0098761	cellular response to interleukin-7	3/1068	15/18722	0.0503639069393446	0.136564644143067	LSP1/YBX1/BTK	3
GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	3/1068	15/18722	0.0503639069393446	0.136564644143067	TGFB1/NCOR2/STAT3	3
GO:1905146	lysosomal protein catabolic process	3/1068	15/18722	0.0503639069393446	0.136564644143067	TPP1/LAMP2/LRP1	3
GO:2001028	positive regulation of endothelial cell chemotaxis	3/1068	15/18722	0.0503639069393446	0.136564644143067	TMSB4X/LGMN/VEGFA	3
GO:2001279	regulation of unsaturated fatty acid biosynthetic process	3/1068	15/18722	0.0503639069393446	0.136564644143067	CD74/FABP5/IL1B	3
GO:0042692	muscle cell differentiation	30/1068	384/18722	0.0505459913154906	0.136989537487889	GPX1/CD9/CD81/HAMP/SOD2/CD53/MEF2A/PLD3/SLC8A1/ID2/PLEKHO1/MEF2C/ARRB2/RB1/YBX1/VEGFA/TGFB1/ENG/QKI/NINJ1/PRKAR1A/PAK1/SKI/FLII/AKAP13/RGS2/PIAS1/FLOT1/PLEC/BHLHE41	30
GO:0009132	nucleoside diphosphate metabolic process	12/1068	124/18722	0.0507885164987758	0.137577728427407	NUPR1/FBP1/HIF1A/P2RX7/DDIT4/ENTPD1/PRKAG2/ADPGK/STAT3/LDHA/PGK1/PKM	12
GO:0003015	heart process	21/1068	251/18722	0.0510891382706389	0.137633104196618	GPX1/CXCR4/MEF2A/SLC8A1/GNAI2/FLNA/CELF2/HBEGF/ADORA3/KCNE3/JAK2/ATP1B1/VEGFB/CALM3/GSTO1/GSN/GAA/AKAP13/CDC42/RGS2/ATP1A1	21
GO:0032878	regulation of establishment or maintenance of cell polarity	4/1068	25/18722	0.0511915567313961	0.137633104196618	PTK2B/SHTN1/ROCK1/GSN	4
GO:0033622	integrin activation	4/1068	25/18722	0.0511915567313961	0.137633104196618	PLEK/FERMT3/PTGER4/TLN1	4
GO:0046039	GTP metabolic process	4/1068	25/18722	0.0511915567313961	0.137633104196618	RHOA/RHOQ/LRRK2/IMPDH1	4
GO:0060706	cell differentiation involved in embryonic placenta development	4/1068	25/18722	0.0511915567313961	0.137633104196618	ST14/PRDM1/STK4/SOCS3	4
GO:0072012	glomerulus vasculature development	4/1068	25/18722	0.0511915567313961	0.137633104196618	PECAM1/NOTCH2/IL6R/EGR1	4
GO:0086013	membrane repolarization during cardiac muscle cell action potential	4/1068	25/18722	0.0511915567313961	0.137633104196618	FLNA/KCNE3/ATP1B1/ATP1A1	4
GO:0086064	cell communication by electrical coupling involved in cardiac conduction	4/1068	25/18722	0.0511915567313961	0.137633104196618	SLC8A1/ATP1B1/CALM3/ATP1A1	4
GO:0090312	positive regulation of protein deacetylation	4/1068	25/18722	0.0511915567313961	0.137633104196618	VEGFA/JDP2/BCL6/LRRK2	4
GO:1900078	positive regulation of cellular response to insulin stimulus	4/1068	25/18722	0.0511915567313961	0.137633104196618	SORL1/GNAI2/OSBPL8/PAK1	4
GO:1901798	positive regulation of signal transduction by p53 class mediator	4/1068	25/18722	0.0511915567313961	0.137633104196618	SPRED1/ATM/DDX5/ZNF385A	4
GO:1902993	positive regulation of amyloid precursor protein catabolic process	4/1068	25/18722	0.0511915567313961	0.137633104196618	LYN/IFNGR1/ABCG1/PICALM	4
GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA	4/1068	25/18722	0.0511915567313961	0.137633104196618	TGFB1/NCOR2/STAT3/DDX5	4
GO:1903901	negative regulation of viral life cycle	4/1068	25/18722	0.0511915567313961	0.137633104196618	BST2/IFITM3/CIITA/GSN	4
GO:1904754	positive regulation of vascular associated smooth muscle cell migration	4/1068	25/18722	0.0511915567313961	0.137633104196618	DOCK4/LRP1/IQGAP1/PAK1	4
GO:1903036	positive regulation of response to wounding	8/1068	72/18722	0.0520006841345534	0.139479667102119	GRN/CXCR4/CLEC7A/CD36/FLNA/HBEGF/HPSE/LRP1	8
GO:0002691	regulation of cellular extravasation	5/1068	36/18722	0.052007614938744	0.139479667102119	PTGER4/PTAFR/ADAM8/ITGA4/BST1	5
GO:0036314	response to sterol	5/1068	36/18722	0.052007614938744	0.139479667102119	CCL3/TGFB1/TGFBR2/ABCA1/TGFBR1	5
GO:0090313	regulation of protein targeting to membrane	5/1068	36/18722	0.052007614938744	0.139479667102119	ITGB2/CIB1/PRNP/ITGAM/PAK1	5
GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	5/1068	36/18722	0.052007614938744	0.139479667102119	CD74/CD44/SKIL/BID/ZNF385A	5
GO:0002673	regulation of acute inflammatory response	6/1068	48/18722	0.0541119590483	0.144907261054405	C3/HLA-E/ALOX5AP/BTK/ADAM8/IL1B	6
GO:0045912	negative regulation of carbohydrate metabolic process	6/1068	48/18722	0.0541119590483	0.144907261054405	NUPR1/PLEK/FBP1/TGFB1/DDIT4/STAT3	6
GO:0090311	regulation of protein deacetylation	6/1068	48/18722	0.0541119590483	0.144907261054405	VEGFA/JDP2/BCL6/SPRED1/LRRK2/SKI	6
GO:0009141	nucleoside triphosphate metabolic process	11/1068	112/18722	0.0547731442999316	0.146518441245627	TMSB4X/TREM2/SAMHD1/RHOA/RHOQ/TGFB1/ATP6V1A/LRRK2/IMPDH1/PRKAG2/STAT3	11
GO:0010633	negative regulation of epithelial cell migration	11/1068	112/18722	0.0547731442999316	0.146518441245627	APOE/MEF2C/RHOA/CORO1C/KLF4/SP100/TGFB1/VASH1/SPRED1/RGCC/SVBP	11
GO:0023061	signal release	35/1068	463/18722	0.0547950730974195	0.146518441245627	SPP1/HLA-DRB1/GLUL/PPT1/HIF1A/MEF2C/LYN/UCP2/RETN/SYK/LILRB1/ALOX5/RAP1A/TCIRG1/BTK/MCTP1/JAK2/CYB5R4/TRPM2/LRRK2/RAB8B/SLC30A1/STXBP2/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/ABCA1/STX4/CALM3/NR4A1/ACSL4/KIF5B	35
GO:0007517	muscle organ development	26/1068	327/18722	0.0549908088492978	0.146968996805751	GPX1/NUPR1/FOS/MEF2A/MEF2C/RB1/VAMP5/GPCPD1/RHOA/HBEGF/TGFB1/ENG/SAP30/FOXN2/FHL3/BTG2/SERP1/DDX5/TGFBR1/SKI/NR4A1/ATF3/FLOT1/MYL6/EGR1/PLEC	26
GO:0009166	nucleotide catabolic process	8/1068	73/18722	0.0556172066688846	0.148496015430629	TYMP/SAMHD1/UPP1/NUDT3/DPYD/HPRT1/MBD4/ACAT1	8
GO:0035773	insulin secretion involved in cellular response to glucose stimulus	8/1068	73/18722	0.0556172066688846	0.148496015430629	HLA-DRB1/HIF1A/UCP2/RAC1/ABCG1/LRP1/STX4/KIF5B	8
GO:0007409	axonogenesis	32/1068	418/18722	0.0558751739298338	0.149110998281594	APOE/SPP1/ALCAM/ACTB/SKIL/PLXNC1/DPYSL2/TWF2/NR4A2/RHOG/VEGFA/PLXND1/NOTCH2/ITGA4/ARHGAP4/VASP/S100A6/CYFIP1/RAC1/SHTN1/LRP1/NUMB/RTN4/PAK2/PAK1/PICALM/RAB10/DBNL/FLOT1/RAB8A/KIF5B/B3GNT2	32
GO:0015908	fatty acid transport	9/1068	86/18722	0.0561365505657403	0.149734467055232	APOE/FABP5/PLIN2/CD36/SYK/ACSL1/IL1B/CPT1A/ACSL4	9
GO:0006839	mitochondrial transport	21/1068	254/18722	0.0565855163312182	0.150857433855362	TSPO/CHCHD10/UCP2/HSPA1A/SLC25A24/ACAA2/BID/MPC1/SFXN3/LRRK2/BNIP3L/SLC35F6/STAT3/CPT1A/BLOC1S2/ALKBH7/OXA1L/BAX/MICU1/UBE2D3/PPIF	21
GO:0009260	ribonucleotide biosynthetic process	16/1068	182/18722	0.0568269895459735	0.151426387945715	TMSB4X/TREM2/PPT1/UPP1/PDK4/TGFB1/ATP6V1A/IMPDH1/PRKAG2/ACSL1/PAPSS1/HPRT1/STAT3/ACAT1/ADCY7/ACSL4	16
GO:0050770	regulation of axonogenesis	14/1068	154/18722	0.0571756127821853	0.152280161190855	SPP1/SKIL/PLXNC1/TWF2/VEGFA/PLXND1/ARHGAP4/CYFIP1/SHTN1/LRP1/RTN4/PAK2/PAK1/DBNL	14
GO:0003176	aortic valve development	5/1068	37/18722	0.0574292901485562	0.152729644968758	RB1/TNFRSF1B/TGFB1/TNFRSF1A/ROCK1	5
GO:0033363	secretory granule organization	5/1068	37/18722	0.0574292901485562	0.152729644968758	SRGN/BLOC1S1/ABCG1/ABCA1/BLOC1S2	5
GO:1900016	negative regulation of cytokine production involved in inflammatory response	5/1068	37/18722	0.0574292901485562	0.152729644968758	TREM2/PYCARD/LILRB4/SIRPA/ADCY7	5
GO:0044106	cellular amine metabolic process	11/1068	113/18722	0.0577036064403729	0.153152714801627	ITGB2/SLC7A7/HNMT/IL4I1/NR4A2/OAZ1/KYNU/ITGAM/SAT1/HPRT1/SAT2	11
GO:0016054	organic acid catabolic process	20/1068	240/18722	0.0577544195236211	0.153152714801627	GLUL/SDS/HNMT/IL4I1/DDAH2/SDSL/KYNU/GNPDA1/ACAA2/GLS/ABHD2/AKR1A1/ACAT1/CPT1A/FAH/NPL/NAGK/PLA2G15/SCP2/HSD17B4	20
GO:0060998	regulation of dendritic spine development	7/1068	61/18722	0.057825326849649	0.153152714801627	APOE/MEF2C/ACTR2/TANC2/ARF6/UBE3A/DBNL	7
GO:0002092	positive regulation of receptor internalization	4/1068	26/18722	0.0578721989400512	0.153152714801627	CD63/ARRB2/SYK/VEGFA	4
GO:0006027	glycosaminoglycan catabolic process	4/1068	26/18722	0.0578721989400512	0.153152714801627	CD44/TGFB1/IDS/GNS	4
GO:0009164	nucleoside catabolic process	4/1068	26/18722	0.0578721989400512	0.153152714801627	UPP1/DPYD/APOBEC3C/APOBEC3A	4
GO:0043094	cellular metabolic compound salvage	4/1068	26/18722	0.0578721989400512	0.153152714801627	UPP1/PDXK/HPRT1/TK2	4
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	4/1068	26/18722	0.0578721989400512	0.153152714801627	CD81/PTPRC/CMTM3/RAB29	4
GO:0060669	embryonic placenta morphogenesis	4/1068	26/18722	0.0578721989400512	0.153152714801627	GRB2/ZFP36L1/ST14/SOCS3	4
GO:0070920	regulation of production of small RNA involved in gene silencing by RNA	4/1068	26/18722	0.0578721989400512	0.153152714801627	TGFB1/NCOR2/STAT3/DDX5	4
GO:0006692	prostanoid metabolic process	6/1068	49/18722	0.0588213421003418	0.154869728004879	CD74/FABP5/TBXAS1/PTGS1/IL1B/TNFRSF1A	6
GO:0006693	prostaglandin metabolic process	6/1068	49/18722	0.0588213421003418	0.154869728004879	CD74/FABP5/TBXAS1/PTGS1/IL1B/TNFRSF1A	6
GO:0045778	positive regulation of ossification	6/1068	49/18722	0.0588213421003418	0.154869728004879	ISG15/SLC8A1/MEF2C/ALOX5/P2RX7/TGFB1	6
GO:0060964	regulation of gene silencing by miRNA	6/1068	49/18722	0.0588213421003418	0.154869728004879	ZFP36/NEAT1/TGFB1/NCOR2/STAT3/DDX5	6
GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	6/1068	49/18722	0.0588213421003418	0.154869728004879	JUN/GNAI2/JAK2/NQO2/MMP2/PAK1	6
GO:1904894	positive regulation of receptor signaling pathway via STAT	6/1068	49/18722	0.0588213421003418	0.154869728004879	CD300A/IL10RA/TGFB1/JAK2/IL6R/PTK2B	6
GO:0030048	actin filament-based movement	12/1068	127/18722	0.0589036615108714	0.154869728004879	FLNA/WIPF1/WAS/MYO5A/MYO9B/MYO1F/KCNE3/MYO1G/SHTN1/GSN/MYL6/ATP1A1	12
GO:0030968	endoplasmic reticulum unfolded protein response	8/1068	74/18722	0.059389936447647	0.154869728004879	SERP1/EIF2AK2/ERO1A/PPP1R15A/HERPUD1/BAX/ATF3/PIK3R1	8
GO:0001845	phagolysosome assembly	3/1068	16/18722	0.0594394378610274	0.154869728004879	CORO1A/ARL8B/RAB7A	3
GO:0002827	positive regulation of T-helper 1 type immune response	3/1068	16/18722	0.0594394378610274	0.154869728004879	IL18/SLC11A1/IL1B	3
GO:0003084	positive regulation of systemic arterial blood pressure	3/1068	16/18722	0.0594394378610274	0.154869728004879	CYBA/RHOA/WNK1	3
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	3/1068	16/18722	0.0594394378610274	0.154869728004879	ENG/TGFBR2/TGFBR1	3
GO:0006828	manganese ion transport	3/1068	16/18722	0.0594394378610274	0.154869728004879	SLC11A1/TRPM2/ATP2C1	3
GO:0009074	aromatic amino acid family catabolic process	3/1068	16/18722	0.0594394378610274	0.154869728004879	IL4I1/KYNU/FAH	3
GO:0010819	regulation of T cell chemotaxis	3/1068	16/18722	0.0594394378610274	0.154869728004879	ADAM17/ADAM10/WNK1	3
GO:0010919	regulation of inositol phosphate biosynthetic process	3/1068	16/18722	0.0594394378610274	0.154869728004879	PLEK/PTAFR/PTK2B	3
GO:0019377	glycolipid catabolic process	3/1068	16/18722	0.0594394378610274	0.154869728004879	GALC/HEXA/GM2A	3
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	3/1068	16/18722	0.0594394378610274	0.154869728004879	HIF1A/ITGA5/IL1B	3
GO:0034116	positive regulation of heterotypic cell-cell adhesion	3/1068	16/18722	0.0594394378610274	0.154869728004879	CD44/IL1B/FLOT1	3
GO:0034374	low-density lipoprotein particle remodeling	3/1068	16/18722	0.0594394378610274	0.154869728004879	APOE/PLA2G7/ABCG1	3
GO:0044849	estrous cycle	3/1068	16/18722	0.0594394378610274	0.154869728004879	NCOR2/TRPM2/EGR1	3
GO:0060330	regulation of response to interferon-gamma	3/1068	16/18722	0.0594394378610274	0.154869728004879	PARP9/NR1H3/PARP14	3
GO:0060334	regulation of interferon-gamma-mediated signaling pathway	3/1068	16/18722	0.0594394378610274	0.154869728004879	PARP9/NR1H3/PARP14	3
GO:0061684	chaperone-mediated autophagy	3/1068	16/18722	0.0594394378610274	0.154869728004879	LAMP2/CTSA/PLK3	3
GO:0070242	thymocyte apoptotic process	3/1068	16/18722	0.0594394378610274	0.154869728004879	HIF1A/ADAM8/BAX	3
GO:0097202	activation of cysteine-type endopeptidase activity	3/1068	16/18722	0.0594394378610274	0.154869728004879	LGMN/PYCARD/IFI16	3
GO:1901163	regulation of trophoblast cell migration	3/1068	16/18722	0.0594394378610274	0.154869728004879	TIMP1/ARHGDIB/VEGFA	3
GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	3/1068	16/18722	0.0594394378610274	0.154869728004879	CD74/CD44/ZNF385A	3
GO:1905906	regulation of amyloid fibril formation	3/1068	16/18722	0.0594394378610274	0.154869728004879	APOE/TREM2/PFDN5	3
GO:2000765	regulation of cytoplasmic translation	3/1068	16/18722	0.0594394378610274	0.154869728004879	ZNF385A/PKM/CNBP	3
GO:2001212	regulation of vasculogenesis	3/1068	16/18722	0.0594394378610274	0.154869728004879	RAP1A/RIN2/RRAS	3
GO:2001224	positive regulation of neuron migration	3/1068	16/18722	0.0594394378610274	0.154869728004879	FLNA/ARHGEF2/SHTN1	3
GO:0009152	purine ribonucleotide biosynthetic process	15/1068	169/18722	0.0595568701757214	0.154984034284721	TMSB4X/TREM2/PPT1/PDK4/TGFB1/ATP6V1A/IMPDH1/PRKAG2/ACSL1/PAPSS1/HPRT1/STAT3/ACAT1/ADCY7/ACSL4	15
GO:0007029	endoplasmic reticulum organization	9/1068	87/18722	0.0595981970238689	0.154984034284721	LRRK2/SHTN1/ATL3/EMC3/TRAM1/RTN4/RTN3/RAB10/CAMLG	9
GO:0150104	transport across blood-brain barrier	9/1068	87/18722	0.0595981970238689	0.154984034284721	APOE/FABP5/CD36/SLCO2B1/ABCC3/SLC6A6/SLC2A3/LRP1/SLC1A3	9
GO:1901606	alpha-amino acid catabolic process	9/1068	87/18722	0.0595981970238689	0.154984034284721	GLUL/SDS/IL4I1/DDAH2/SDSL/KYNU/GLS/ACAT1/FAH	9
GO:0009116	nucleoside metabolic process	7/1068	62/18722	0.062128716377023	0.161486779176501	TYMP/UPP1/DPYD/APOBEC3C/APOBEC3A/HPRT1/TK2	7
GO:0006576	cellular biogenic amine metabolic process	10/1068	101/18722	0.0622315399505695	0.16167616252926	ITGB2/HNMT/IL4I1/NR4A2/OAZ1/KYNU/ITGAM/SAT1/HPRT1/SAT2	10
GO:0046546	development of primary male sexual characteristics	13/1068	142/18722	0.0622763618129722	0.161714748961885	NUPR1/LHFPL2/FLNA/MGST1/TNFSF10/ERCC1/SGPL1/FNDC3A/ARID4A/TGFBR1/BAX/HSD17B4/RAB13	13
GO:0051962	positive regulation of nervous system development	22/1068	272/18722	0.0629703303141658	0.163438144480634	CXCR4/TSPO/ID2/SKIL/HIF1A/LYN/ACTR2/PLXNC1/TWF2/TLR2/TNFRSF1B/VEGFA/PLXND1/TGFB1/IL1B/CYFIP1/SHTN1/LRP1/NUMB/PAK1/SPEN/DBNL	22
GO:0010232	vascular transport	9/1068	88/18722	0.0631937485679428	0.16393916695799	APOE/FABP5/CD36/SLCO2B1/ABCC3/SLC6A6/SLC2A3/LRP1/SLC1A3	9
GO:2001259	positive regulation of cation channel activity	8/1068	75/18722	0.0633199750255242	0.164187691128173	TMSB4X/TREM2/CTSS/IFNGR2/KCNE3/CALM3/GSTO1/KIF5B	8
GO:0043268	positive regulation of potassium ion transport	6/1068	50/18722	0.0637676066407161	0.165189632949258	TREM2/FLNA/ATP1B1/WNK1/KIF5B/ATP1B3	6
GO:0070231	T cell apoptotic process	6/1068	50/18722	0.0637676066407161	0.165189632949258	LGALS3/LGALS9/HIF1A/ADAM8/TSC22D3/BAX	6
GO:0043279	response to alkaloid	11/1068	115/18722	0.0638710905147831	0.16537831306035	AIF1/CXCR4/SLC8A1/HNMT/PEA15/PTK2B/CPT1A/FOSB/SLC1A3/TMED10/UBE3A	11
GO:0042593	glucose homeostasis	21/1068	258/18722	0.0645444500825545	0.167041655945067	HLA-DRB1/LGALS1/FABP5/CYBA/TREM2/HIF1A/UCP2/PDK4/OAS1/ALOX5/CYB5R4/PRCP/STAT3/RAC1/ABCG1/LRP1/SESN3/STX4/CEBPA/KIF5B/PIK3R1	21
GO:0046890	regulation of lipid biosynthetic process	15/1068	171/18722	0.0646030307125019	0.167113113003193	APOE/APOC1/CD74/FABP5/C3/TSPO/ASAH1/PDK4/CREBL2/LPGAT1/NR1H3/IL1B/ABCG1/EGR1/ATP1A1	15
GO:0002825	regulation of T-helper 1 type immune response	4/1068	27/18722	0.0649944389193034	0.167323469660573	HAVCR2/IL18/SLC11A1/IL1B	4
GO:0007026	negative regulation of microtubule depolymerization	4/1068	27/18722	0.0649944389193034	0.167323469660573	CIB1/ARHGEF2/APC/TAOK1	4
GO:0010758	regulation of macrophage chemotaxis	4/1068	27/18722	0.0649944389193034	0.167323469660573	C5AR1/CSF1R/C3AR1/PTK2B	4
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	4/1068	27/18722	0.0649944389193034	0.167323469660573	SLC8A1/ATP1B1/CALM3/GSTO1	4
GO:0018904	ether metabolic process	4/1068	27/18722	0.0649944389193034	0.167323469660573	PLA2G7/LPCAT2/NCEH1/ALOX5	4
GO:0042402	cellular biogenic amine catabolic process	4/1068	27/18722	0.0649944389193034	0.167323469660573	HNMT/IL4I1/KYNU/SAT1	4
GO:0048873	homeostasis of number of cells within a tissue	4/1068	27/18722	0.0649944389193034	0.167323469660573	LIPA/CORO1A/SASH3/BAX	4
GO:0061437	renal system vasculature development	4/1068	27/18722	0.0649944389193034	0.167323469660573	PECAM1/NOTCH2/IL6R/EGR1	4
GO:0061440	kidney vasculature development	4/1068	27/18722	0.0649944389193034	0.167323469660573	PECAM1/NOTCH2/IL6R/EGR1	4
GO:1903421	regulation of synaptic vesicle recycling	4/1068	27/18722	0.0649944389193034	0.167323469660573	LRRK2/CYFIP1/CALM3/ROCK1	4
GO:0071478	cellular response to radiation	16/1068	186/18722	0.0664370667758759	0.170955847554901	CYBA/TIMP1/HAMP/IFI16/GRB2/CARD16/CRIP1/NAMPT/MMP2/CDKN1A/ERCC1/ATM/RHOB/BAX/EGR1/PIK3R1	16
GO:0033500	carbohydrate homeostasis	21/1068	259/18722	0.0666493790800391	0.171420423982789	HLA-DRB1/LGALS1/FABP5/CYBA/TREM2/HIF1A/UCP2/PDK4/OAS1/ALOX5/CYB5R4/PRCP/STAT3/RAC1/ABCG1/LRP1/SESN3/STX4/CEBPA/KIF5B/PIK3R1	21
GO:0051781	positive regulation of cell division	9/1068	89/18722	0.0669240802318805	0.172044943749989	RHOA/YBX1/VEGFA/TGFB1/IL1B/VEGFB/NUP62/CDC42/CHMP3	9
GO:0018107	peptidyl-threonine phosphorylation	11/1068	116/18722	0.0671097395972332	0.172357998508648	TGFB1/DDIT4/TGFBR2/SPRED1/LRRK2/PRKAG2/CALM3/TGFBR1/CAB39/ROCK1/WNK1	11
GO:0043200	response to amino acid	11/1068	116/18722	0.0671097395972332	0.172357998508648	CYBA/CYBB/LYN/RHOA/TMBIM6/RRAGD/MMP2/LAMTOR4/CEBPB/SESN3/LAMTOR2	11
GO:0043536	positive regulation of blood vessel endothelial cell migration	8/1068	76/18722	0.0674081733598914	0.173042104400558	TMSB4X/HMOX1/HIF1A/CIB1/VEGFA/TGFB1/STAT5A/ADAM17	8
GO:0006956	complement activation	12/1068	130/18722	0.0678397853518579	0.174067276157216	C1QB/TREM2/C3/C1QA/C1QC/CFD/A2M/C2/VSIG4/IL1B/SERPING1/RGCC	12
GO:0006636	unsaturated fatty acid biosynthetic process	6/1068	51/18722	0.0689508708602242	0.175937954659448	CD74/FABP5/TBXAS1/SCD/PTGS1/IL1B	6
GO:0014009	glial cell proliferation	6/1068	51/18722	0.0689508708602242	0.175937954659448	TREM2/TSPO/LYN/PTK2B/IL1B/SKI	6
GO:0014013	regulation of gliogenesis	10/1068	103/18722	0.0691784508713062	0.175937954659448	TREM2/CXCR4/TSPO/ID2/LYN/TLR2/TNFRSF1B/TGFB1/IL1B/SKI	10
GO:0045923	positive regulation of fatty acid metabolic process	5/1068	39/18722	0.0692052555688923	0.175937954659448	CD74/LPGAT1/NR1H3/IL1B/CPT1A	5
GO:0051084	'de novo' posttranslational protein folding	5/1068	39/18722	0.0692052555688923	0.175937954659448	CD74/HSPA1A/ERO1A/HSPH1/SDF2L1	5
GO:1901021	positive regulation of calcium ion transmembrane transporter activity	5/1068	39/18722	0.0692052555688923	0.175937954659448	VMP1/KCNE3/ATP1B1/CALM3/GSTO1	5
GO:0010715	regulation of extracellular matrix disassembly	3/1068	17/18722	0.0692209558454424	0.175937954659448	CST3/TGFB1/LRP1	3
GO:0021756	striatum development	3/1068	17/18722	0.0692209558454424	0.175937954659448	ZSWIM6/LRRK2/HPRT1	3
GO:0034349	glial cell apoptotic process	3/1068	17/18722	0.0692209558454424	0.175937954659448	TREM2/RB1/BID	3
GO:0035729	cellular response to hepatocyte growth factor stimulus	3/1068	17/18722	0.0692209558454424	0.175937954659448	LGMN/HGF/APPL1	3
GO:0038065	collagen-activated signaling pathway	3/1068	17/18722	0.0692209558454424	0.175937954659448	SYK/OSCAR/JAK2	3
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	3/1068	17/18722	0.0692209558454424	0.175937954659448	SH2B3/PARP14/SOCS3	3
GO:0043117	positive regulation of vascular permeability	3/1068	17/18722	0.0692209558454424	0.175937954659448	APOE/VEGFA/TGFB1	3
GO:0045198	establishment of epithelial cell apical/basal polarity	3/1068	17/18722	0.0692209558454424	0.175937954659448	MSN/RHOA/CDC42	3
GO:0060644	mammary gland epithelial cell differentiation	3/1068	17/18722	0.0692209558454424	0.175937954659448	ID2/HIF1A/CEBPB	3
GO:0060977	coronary vasculature morphogenesis	3/1068	17/18722	0.0692209558454424	0.175937954659448	VEGFA/SPRED1/TGFBR1	3
GO:0061158	3'-UTR-mediated mRNA destabilization	3/1068	17/18722	0.0692209558454424	0.175937954659448	ZFP36L2/ZFP36/ZFP36L1	3
GO:0061450	trophoblast cell migration	3/1068	17/18722	0.0692209558454424	0.175937954659448	TIMP1/ARHGDIB/VEGFA	3
GO:0090399	replicative senescence	3/1068	17/18722	0.0692209558454424	0.175937954659448	CDKN1A/ERCC1/ATM	3
GO:2000811	negative regulation of anoikis	3/1068	17/18722	0.0692209558454424	0.175937954659448	PDK4/ITGA5/MCL1	3
GO:0014902	myotube differentiation	11/1068	117/18722	0.0704525779384653	0.178984044517871	GPX1/CD9/CD81/CD53/PLD3/PLEKHO1/MEF2C/SKI/FLOT1/PLEC/BHLHE41	11
GO:0006612	protein targeting to membrane	12/1068	131/18722	0.0710043132160434	0.180300834877068	ITGB2/SSR3/SDCBP/CIB1/PRNP/ITGAM/NCF1/RAB8B/SSR1/TRAM1/PAK1/ATG3	12
GO:0048857	neural nucleus development	7/1068	64/18722	0.0713064333263955	0.180897749990235	YWHAH/ACTB/GNB4/RHOA/MBP/CALM3/CDC42	7
GO:1900076	regulation of cellular response to insulin stimulus	7/1068	64/18722	0.0713064333263955	0.180897749990235	SORL1/GNAI2/LPL/OSBPL8/SOCS3/IL1B/PAK1	7
GO:0006972	hyperosmotic response	4/1068	28/18722	0.0725509374327277	0.183623291926359	HNMT/RCSD1/ARHGEF2/MICU1	4
GO:0009065	glutamine family amino acid catabolic process	4/1068	28/18722	0.0725509374327277	0.183623291926359	GLUL/DDAH2/GLS/FAH	4
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	4/1068	28/18722	0.0725509374327277	0.183623291926359	PTPRJ/DUSP3/NUP62/RAB7A	4
GO:0060325	face morphogenesis	4/1068	28/18722	0.0725509374327277	0.183623291926359	MMP2/RRAS/SGPL1/SKI	4
GO:0086011	membrane repolarization during action potential	4/1068	28/18722	0.0725509374327277	0.183623291926359	FLNA/KCNE3/ATP1B1/ATP1A1	4
GO:0043271	negative regulation of ion transport	14/1068	160/18722	0.0735461010448061	0.186054740383391	HAMP/TMBIM6/LILRB1/LILRB2/KCNE3/CD33/PTK2B/SLC30A1/CALM3/CAB39/GSTO1/RGS2/WNK1/PPIF	14
GO:0009308	amine metabolic process	11/1068	118/18722	0.073900166333604	0.186775315005212	ITGB2/SLC7A7/HNMT/IL4I1/NR4A2/OAZ1/KYNU/ITGAM/SAT1/HPRT1/SAT2	11
GO:0030203	glycosaminoglycan metabolic process	11/1068	118/18722	0.073900166333604	0.186775315005212	CD44/DSE/HGF/HS3ST1/TGFB1/CSGALNACT2/IDS/GNS/IL1B/HEXA/B3GNT2	11
GO:0042445	hormone metabolic process	18/1068	218/18722	0.0739666914958816	0.186855930389409	SPP1/CTSB/CTSZ/TSPO/HIF1A/ALDH1A1/SCPEP1/IL4I1/ATP6AP2/HSD17B11/SRD5A3/RDH11/SGPL1/DHRS3/DHRS4/EGR1/ATP1A1/HSD17B4	18
GO:0045667	regulation of osteoblast differentiation	12/1068	132/18722	0.0742626951790462	0.187515911645359	MEF2C/HGF/TCIRG1/PDLIM7/RASSF2/IL6R/ATP6AP1/CEBPB/DDX5/CEBPA/SKI/CLIC1	12
GO:0030514	negative regulation of BMP signaling pathway	6/1068	52/18722	0.0743706651956703	0.187700705984957	SORL1/SKIL/HTRA1/UBE2D1/SKI/UBE2D3	6
GO:0021537	telencephalon development	20/1068	248/18722	0.0752222840296668	0.189761311184704	CXCR4/SLC8A1/ID2/PHACTR1/HIF1A/BCL2A1/FLNA/RHOA/ATF5/ZMIZ1/ZSWIM6/LRRK2/BTG2/HPRT1/LRP1/NUMB/RTN4/SKI/BAX/KIF5B	20
GO:0009394	2'-deoxyribonucleotide metabolic process	5/1068	40/18722	0.0755557070350492	0.190246661297772	TYMP/SAMHD1/UPP1/DPYD/MBD4	5
GO:0010863	positive regulation of phospholipase C activity	5/1068	40/18722	0.0755557070350492	0.190246661297772	C5AR1/CD86/PTAFR/GNA15/GNAQ	5
GO:0071526	semaphorin-plexin signaling pathway	5/1068	40/18722	0.0755557070350492	0.190246661297772	PLXNC1/FLNA/PLXND1/RAC1/ARHGDIA	5
GO:1901223	negative regulation of NIK/NF-kappaB signaling	5/1068	40/18722	0.0755557070350492	0.190246661297772	TMSB4X/LITAF/SPI1/IFI35/RASSF2	5
GO:0043537	negative regulation of blood vessel endothelial cell migration	8/1068	78/18722	0.0760611913219843	0.191430125174173	APOE/MEF2C/RHOA/KLF4/TGFB1/VASH1/SPRED1/RGCC	8
GO:0015909	long-chain fatty acid transport	7/1068	65/18722	0.0761812337609596	0.191642861246684	APOE/FABP5/PLIN2/CD36/SYK/ACSL1/CPT1A	7
GO:0046390	ribose phosphate biosynthetic process	16/1068	190/18722	0.0770853196701936	0.1938268336162	TMSB4X/TREM2/PPT1/UPP1/PDK4/TGFB1/ATP6V1A/IMPDH1/PRKAG2/ACSL1/PAPSS1/HPRT1/STAT3/ACAT1/ADCY7/ACSL4	16
GO:0010565	regulation of cellular ketone metabolic process	12/1068	133/18722	0.0776153756625491	0.195016930600609	APOC1/CD74/FABP5/SLC7A7/PDK4/NCOR2/LPGAT1/NR1H3/PRKAG2/IL1B/CPT1A/EGR1	12
GO:0046883	regulation of hormone secretion	20/1068	249/18722	0.0776309056579147	0.195016930600609	SPP1/HLA-DRB1/GLUL/HIF1A/UCP2/RETN/ALOX5/TCIRG1/JAK2/TRPM2/RAB8B/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/STX4/ACSL4/KIF5B	20
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	3/1068	18/18722	0.0796754924690417	0.198581504555635	TREM2/PTPRC/PTPN6	3
GO:0006595	polyamine metabolic process	3/1068	18/18722	0.0796754924690417	0.198581504555635	OAZ1/SAT1/SAT2	3
GO:0006957	complement activation, alternative pathway	3/1068	18/18722	0.0796754924690417	0.198581504555635	C3/CFD/VSIG4	3
GO:0031643	positive regulation of myelination	3/1068	18/18722	0.0796754924690417	0.198581504555635	HGF/ITGAX/TNFRSF1B	3
GO:0050665	hydrogen peroxide biosynthetic process	3/1068	18/18722	0.0796754924690417	0.198581504555635	CYBA/SOD2/STAT3	3
GO:0051447	negative regulation of meiotic cell cycle	3/1068	18/18722	0.0796754924690417	0.198581504555635	DUSP1/PRKAR1A/PRKACB	3
GO:0051895	negative regulation of focal adhesion assembly	3/1068	18/18722	0.0796754924690417	0.198581504555635	CORO1C/LRP1/RCC2	3
GO:0060391	positive regulation of SMAD protein signal transduction	3/1068	18/18722	0.0796754924690417	0.198581504555635	TGFB1/JAK2/TGFBR1	3
GO:0060457	negative regulation of digestive system process	3/1068	18/18722	0.0796754924690417	0.198581504555635	HAMP/NR1H3/WNK1	3
GO:0060749	mammary gland alveolus development	3/1068	18/18722	0.0796754924690417	0.198581504555635	ID2/HIF1A/VEGFA	3
GO:0061377	mammary gland lobule development	3/1068	18/18722	0.0796754924690417	0.198581504555635	ID2/HIF1A/VEGFA	3
GO:0071360	cellular response to exogenous dsRNA	3/1068	18/18722	0.0796754924690417	0.198581504555635	IFIT1/IFIH1/FLOT1	3
GO:0150118	negative regulation of cell-substrate junction organization	3/1068	18/18722	0.0796754924690417	0.198581504555635	CORO1C/LRP1/RCC2	3
GO:1900242	regulation of synaptic vesicle endocytosis	3/1068	18/18722	0.0796754924690417	0.198581504555635	LRRK2/CALM3/ROCK1	3
GO:1900424	regulation of defense response to bacterium	3/1068	18/18722	0.0796754924690417	0.198581504555635	CYBA/GRN/HAVCR2	3
GO:1902001	fatty acid transmembrane transport	3/1068	18/18722	0.0796754924690417	0.198581504555635	CD36/ACSL1/CPT1A	3
GO:1903209	positive regulation of oxidative stress-induced cell death	3/1068	18/18722	0.0796754924690417	0.198581504555635	TLR4/TRPM2/MCL1	3
GO:0071320	cellular response to cAMP	6/1068	53/18722	0.0800259437860176	0.199270878020005	SLC8A1/ZFP36L1/AHR/RAP1A/AQP9/PTAFR	6
GO:2000772	regulation of cellular senescence	6/1068	53/18722	0.0800259437860176	0.199270878020005	B2M/YBX1/ABI3/VASH1/NAMPT/BCL6	6
GO:0046879	hormone secretion	23/1068	295/18722	0.0801698810200061	0.199537213092229	SPP1/HLA-DRB1/GLUL/HIF1A/LYN/UCP2/RETN/ALOX5/TCIRG1/BTK/JAK2/CYB5R4/TRPM2/RAB8B/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/STX4/ACSL4/KIF5B	23
GO:0006766	vitamin metabolic process	10/1068	106/18722	0.0804866395926929	0.199794688229929	LGMN/PLTP/CYP27A1/SLC25A19/SLC2A3/VKORC1/PDXK/AKR1A1/MTHFD2/GSTO1	10
GO:0046620	regulation of organ growth	10/1068	106/18722	0.0804866395926929	0.199794688229929	HAMP/MEF2C/TGFBR2/RUNX1/SASH3/STK4/SERP1/TGFBR1/PAK1/RGS2	10
GO:0010212	response to ionizing radiation	13/1068	148/18722	0.0805222052655984	0.199794688229929	GPX1/CYBA/HAMP/IFI16/GRB2/PTPRC/NAMPT/CDKN1A/ERCC1/ATM/RHOB/BAX/EGR1	13
GO:0009310	amine catabolic process	4/1068	29/18722	0.080532514251315	0.199794688229929	HNMT/IL4I1/KYNU/SAT1	4
GO:0021772	olfactory bulb development	4/1068	29/18722	0.080532514251315	0.199794688229929	ID2/ATF5/LRRK2/SKI	4
GO:0042759	long-chain fatty acid biosynthetic process	4/1068	29/18722	0.080532514251315	0.199794688229929	ALOX5/LTC4S/GPX4/QKI	4
GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	4/1068	29/18722	0.080532514251315	0.199794688229929	CD74/CD44/BID/ZNF385A	4
GO:0006446	regulation of translational initiation	8/1068	79/18722	0.0806264495968229	0.199935809753886	EIF4EBP1/MIF4GD/EIF2AK2/EIF4G3/PPP1R15A/DNAJC3/EIF1/UHMK1	8
GO:0061041	regulation of wound healing	12/1068	134/18722	0.0810627161662294	0.200925317608164	APOE/CD9/CXCR4/CLEC7A/CD36/ALOX5/HBEGF/HPSE/PLAU/SH2B3/SERPING1/TNFAIP3	12
GO:0030193	regulation of blood coagulation	7/1068	66/18722	0.0812463606311655	0.201103377048518	APOE/CD9/CD36/HPSE/PLAU/SH2B3/SERPING1	7
GO:0071300	cellular response to retinoic acid	7/1068	66/18722	0.0812463606311655	0.201103377048518	LYN/TWF2/KLF4/PTK2B/ATM/ABCA1/SETX	7
GO:1905953	negative regulation of lipid localization	7/1068	66/18722	0.0812463606311655	0.201103377048518	APOC1/TREM2/NR1H3/OSBPL8/ABCG1/NFKBIA/ABCA1	7
GO:0001953	negative regulation of cell-matrix adhesion	5/1068	41/18722	0.0822102767564813	0.203069175673244	CORO1C/BCL6/LRP1/RCC2/PIK3R1	5
GO:0042307	positive regulation of protein import into nucleus	5/1068	41/18722	0.0822102767564813	0.203069175673244	FLNA/TGFB1/JAK2/HCLS1/PIK3R1	5
GO:0071634	regulation of transforming growth factor beta production	5/1068	41/18722	0.0822102767564813	0.203069175673244	TYROBP/LGALS9/HIF1A/ATP6AP2/LILRB1	5
GO:2000008	regulation of protein localization to cell surface	5/1068	41/18722	0.0822102767564813	0.203069175673244	TYROBP/KCNAB2/STX4/PICALM/ARF6	5
GO:0030072	peptide hormone secretion	19/1068	236/18722	0.0823039820603012	0.203069175673244	HLA-DRB1/GLUL/HIF1A/UCP2/ALOX5/TCIRG1/JAK2/CYB5R4/TRPM2/RAB8B/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/STX4/ACSL4/KIF5B	19
GO:0048738	cardiac muscle tissue development	19/1068	236/18722	0.0823039820603012	0.203069175673244	HAMP/MEF2A/SLC8A1/ID2/MEF2C/ARRB2/VEGFA/TGFB1/ENG/TGFBR2/RUNX1/NOTCH2/PRKAR1A/TGFBR1/PAK1/AKAP13/CDC42/RGS2/PLEC	19
GO:0048762	mesenchymal cell differentiation	19/1068	236/18722	0.0823039820603012	0.203069175673244	S100A4/STAT1/HIF1A/MEF2C/HGF/FLNA/SDCBP/CORO1C/GLIPR2/TGFB1/ENG/TGFBR2/SPRED1/IL1B/RGCC/DDX5/TGFBR1/RTN4/ROCK1	19
GO:0007589	body fluid secretion	9/1068	93/18722	0.0832044175273116	0.205009605925741	CYBA/HIF1A/USF2/OAS2/VEGFA/NCOR2/NR1H3/STAT5A/WNK1	9
GO:0019217	regulation of fatty acid metabolic process	9/1068	93/18722	0.0832044175273116	0.205009605925741	APOC1/CD74/FABP5/PDK4/LPGAT1/NR1H3/PRKAG2/IL1B/CPT1A	9
GO:1902807	negative regulation of cell cycle G1/S phase transition	9/1068	93/18722	0.0832044175273116	0.205009605925741	GPNMB/RB1/KLF4/PLK3/SLFN11/CDKN1A/RPS27L/ATM/APC	9
GO:0070588	calcium ion transmembrane transport	24/1068	312/18722	0.0844468584859124	0.207902954495639	CYBA/CCL3/SLC8A1/PTPRC/LYN/VMP1/CORO1A/P2RX7/PRNP/KCNE3/PTPN6/TRPM2/ORAI2/ATP1B1/ATP2C1/PTK2B/MCOLN1/ERO1A/CALM3/ORAI3/TMCO1/GSTO1/BAX/MICU1	24
GO:0032526	response to retinoic acid	10/1068	107/18722	0.0844942882151475	0.207902954495639	CTSH/DUSP1/LYN/TWF2/KLF4/PTK2B/IGF2R/ATM/ABCA1/SETX	10
GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	10/1068	107/18722	0.0844942882151475	0.207902954495639	LAPTM5/HSPA1A/PLK3/LRRK2/PTK2B/GABARAP/CEBPA/HERPUD1/PIAS1/SUMO2	10
GO:1901617	organic hydroxy compound biosynthetic process	19/1068	237/18722	0.0849447074171067	0.208915971386831	APOE/ASAH1/PLEK/ZEB2/NR4A2/PLTP/CYP27A1/OSBPL1A/ACAA2/PTAFR/SRD5A3/PRKAG2/PTK2B/MFSD12/PDXK/ABCG1/ACER3/SCP2/APPL1	19
GO:0120193	tight junction organization	8/1068	80/18722	0.0853507458500132	0.209818963374338	MTDH/PECAM1/TGFBR1/PAK2/ROCK1/APC/PLEC/RAB13	8
GO:0001706	endoderm formation	6/1068	54/18722	0.0859150982415242	0.211014051029251	ITGB2/DUSP1/ITGA4/MMP2/ITGA5/DUSP2	6
GO:2000179	positive regulation of neural precursor cell proliferation	6/1068	54/18722	0.0859150982415242	0.211014051029251	CTSZ/HIF1A/GNAI2/LYN/FLNA/VEGFA	6
GO:0061077	chaperone-mediated protein folding	7/1068	67/18722	0.0865011311076555	0.212356734966747	CD74/HSPA1A/FKBP5/CRTAP/ERO1A/HSPH1/SDF2L1	7
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	9/1068	94/18722	0.0876154687253285	0.21499457446197	ACTB/CDKN1A/TNFAIP3/RGCC/ADAM17/APC/CEBPA/CCNL1/CCNI	9
GO:0033138	positive regulation of peptidyl-serine phosphorylation	10/1068	108/18722	0.0886212895332065	0.216336557283241	CD44/ARRB2/VEGFA/TGFB1/CREBL2/STK4/FNIP2/PAK1/HCLS1/FNIP1	10
GO:0007202	activation of phospholipase C activity	4/1068	30/18722	0.0889283129960353	0.216336557283241	C5AR1/CD86/GNA15/GNAQ	4
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	4/1068	30/18722	0.0889283129960353	0.216336557283241	TGFB1/PRKAG2/CALM3/CAB39	4
GO:0031571	mitotic G1 DNA damage checkpoint signaling	4/1068	30/18722	0.0889283129960353	0.216336557283241	PLK3/CDKN1A/RPS27L/ATM	4
GO:0033137	negative regulation of peptidyl-serine phosphorylation	4/1068	30/18722	0.0889283129960353	0.216336557283241	HGF/DDIT4/RASSF2/BAX	4
GO:0036296	response to increased oxygen levels	4/1068	30/18722	0.0889283129960353	0.216336557283241	ATP6V0D1/ATP6V1A/CDKN1A/ATP6AP1	4
GO:0044788	modulation by host of viral process	4/1068	30/18722	0.0889283129960353	0.216336557283241	APOE/IFI27/IGF2R/CFL1	4
GO:0046825	regulation of protein export from nucleus	4/1068	30/18722	0.0889283129960353	0.216336557283241	IFI27/SP100/IL1B/UHMK1	4
GO:0060674	placenta blood vessel development	4/1068	30/18722	0.0889283129960353	0.216336557283241	JUNB/VASH1/NOTCH2/SOCS3	4
GO:0070229	negative regulation of lymphocyte apoptotic process	4/1068	30/18722	0.0889283129960353	0.216336557283241	CD74/HIF1A/BCL6/TSC22D3	4
GO:2000637	positive regulation of gene silencing by miRNA	4/1068	30/18722	0.0889283129960353	0.216336557283241	ZFP36/TGFB1/STAT3/DDX5	4
GO:0006040	amino sugar metabolic process	5/1068	42/18722	0.0891646596363838	0.216336557283241	ALDH1A1/MGAT1/GNPDA1/NPL/NAGK	5
GO:0007212	dopamine receptor signaling pathway	5/1068	42/18722	0.0891646596363838	0.216336557283241	ARRB2/FLNA/GNA15/LRRK2/GNB1	5
GO:0007520	myoblast fusion	5/1068	42/18722	0.0891646596363838	0.216336557283241	CD9/CD81/CD53/PLEKHO1/FLOT1	5
GO:0010677	negative regulation of cellular carbohydrate metabolic process	5/1068	42/18722	0.0891646596363838	0.216336557283241	NUPR1/PLEK/FBP1/DDIT4/STAT3	5
GO:0014912	negative regulation of smooth muscle cell migration	5/1068	42/18722	0.0891646596363838	0.216336557283241	AIF1/MEF2C/RHOA/GNA13/LRP1	5
GO:0019692	deoxyribose phosphate metabolic process	5/1068	42/18722	0.0891646596363838	0.216336557283241	TYMP/SAMHD1/UPP1/DPYD/MBD4	5
GO:0030574	collagen catabolic process	5/1068	42/18722	0.0891646596363838	0.216336557283241	CTSB/CTSS/CST3/PEPD/MMP2	5
GO:0042168	heme metabolic process	5/1068	42/18722	0.0891646596363838	0.216336557283241	TSPO/HMOX1/SLCO2B1/BLVRB/BLVRA	5
GO:0045047	protein targeting to ER	5/1068	42/18722	0.0891646596363838	0.216336557283241	SSR3/SPCS3/MAN1A1/TRAM1/HERPUD1	5
GO:0045687	positive regulation of glial cell differentiation	5/1068	42/18722	0.0891646596363838	0.216336557283241	CXCR4/ID2/TLR2/TNFRSF1B/TGFB1	5
GO:0048489	synaptic vesicle transport	5/1068	42/18722	0.0891646596363838	0.216336557283241	LRRK2/BLOC1S1/BLOC1S2/PICALM/KIF5B	5
GO:1900274	regulation of phospholipase C activity	5/1068	42/18722	0.0891646596363838	0.216336557283241	C5AR1/CD86/PTAFR/GNA15/GNAQ	5
GO:1904037	positive regulation of epithelial cell apoptotic process	5/1068	42/18722	0.0891646596363838	0.216336557283241	ARRB2/JAK2/ITGA4/RGCC/GSN	5
GO:2001222	regulation of neuron migration	5/1068	42/18722	0.0891646596363838	0.216336557283241	PHACTR1/FLNA/ARHGEF2/STAT3/SHTN1	5
GO:0009165	nucleotide biosynthetic process	20/1068	254/18722	0.090444155837385	0.217970443371544	TMSB4X/TREM2/PPT1/UPP1/PDK4/PARP9/KYNU/TGFB1/ATP6V1A/NAMPT/IMPDH1/PRKAG2/ACSL1/PAPSS1/HPRT1/STAT3/ACAT1/ADCY7/TK2/ACSL4	20
GO:0002523	leukocyte migration involved in inflammatory response	3/1068	19/18722	0.0907671583127983	0.217970443371544	ALOX5/ADAM8/NINJ1	3
GO:0006491	N-glycan processing	3/1068	19/18722	0.0907671583127983	0.217970443371544	MGAT4A/ST8SIA4/MAN1A1	3
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	3/1068	19/18722	0.0907671583127983	0.217970443371544	PLK3/CDKN1A/ATM	3
GO:0009081	branched-chain amino acid metabolic process	3/1068	19/18722	0.0907671583127983	0.217970443371544	SDS/SDSL/ACAT1	3
GO:0010544	negative regulation of platelet activation	3/1068	19/18722	0.0907671583127983	0.217970443371544	APOE/CD9/SH2B3	3
GO:0010759	positive regulation of macrophage chemotaxis	3/1068	19/18722	0.0907671583127983	0.217970443371544	C5AR1/CSF1R/C3AR1	3
GO:0010829	negative regulation of glucose transmembrane transport	3/1068	19/18722	0.0907671583127983	0.217970443371544	FABP5/PEA15/IL1B	3
GO:0030050	vesicle transport along actin filament	3/1068	19/18722	0.0907671583127983	0.217970443371544	MYO5A/MYO1F/MYO1G	3
GO:0030220	platelet formation	3/1068	19/18722	0.0907671583127983	0.217970443371544	MEF2C/CIB1/PTPN6	3
GO:0032616	interleukin-13 production	3/1068	19/18722	0.0907671583127983	0.217970443371544	HLA-E/IL18/LGALS9	3
GO:0032656	regulation of interleukin-13 production	3/1068	19/18722	0.0907671583127983	0.217970443371544	HLA-E/IL18/LGALS9	3
GO:0035728	response to hepatocyte growth factor	3/1068	19/18722	0.0907671583127983	0.217970443371544	LGMN/HGF/APPL1	3
GO:0036344	platelet morphogenesis	3/1068	19/18722	0.0907671583127983	0.217970443371544	MEF2C/CIB1/PTPN6	3
GO:0043652	engulfment of apoptotic cell	3/1068	19/18722	0.0907671583127983	0.217970443371544	TREM2/RHOG/RAC1	3
GO:0045019	negative regulation of nitric oxide biosynthetic process	3/1068	19/18722	0.0907671583127983	0.217970443371544	ACP5/TSPO/SIRPA	3
GO:0046794	transport of virus	3/1068	19/18722	0.0907671583127983	0.217970443371544	BST2/SIGLEC1/KPNA3	3
GO:0048245	eosinophil chemotaxis	3/1068	19/18722	0.0907671583127983	0.217970443371544	CCL3/LGALS3/CCL4	3
GO:0051546	keratinocyte migration	3/1068	19/18722	0.0907671583127983	0.217970443371544	HBEGF/ADAM9/ARF6	3
GO:0060216	definitive hemopoiesis	3/1068	19/18722	0.0907671583127983	0.217970443371544	ZFP36L2/LYL1/ADAR	3
GO:1901739	regulation of myoblast fusion	3/1068	19/18722	0.0907671583127983	0.217970443371544	CD53/PLEKHO1/FLOT1	3
GO:1904406	negative regulation of nitric oxide metabolic process	3/1068	19/18722	0.0907671583127983	0.217970443371544	ACP5/TSPO/SIRPA	3
GO:2000251	positive regulation of actin cytoskeleton reorganization	3/1068	19/18722	0.0907671583127983	0.217970443371544	HCK/HCLS1/CDC42	3
GO:0010721	negative regulation of cell development	15/1068	180/18722	0.0908221007396066	0.218005362807347	SPP1/B2M/TREM2/TSPO/SORL1/YWHAH/GBP1/CORO1C/LILRB1/VEGFA/ARHGAP4/IL1B/RTN4/SKI/RCC2	15
GO:0007585	respiratory gaseous exchange by respiratory system	7/1068	68/18722	0.0919445035856054	0.220038153782167	MAFB/HNMT/NR4A2/GLS/PBX3/GAA/ZFAND5	7
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	7/1068	68/18722	0.0919445035856054	0.220038153782167	TMSB4X/TREM2/TGFB1/ATP6V1A/IMPDH1/PRKAG2/STAT3	7
GO:0031640	killing of cells of other organism	7/1068	68/18722	0.0919445035856054	0.220038153782167	LYZ/HAMP/CLEC7A/SYK/P2RX7/TREM1/MYD88	7
GO:0042698	ovulation cycle	7/1068	68/18722	0.0919445035856054	0.220038153782167	ARRB2/RETN/AXL/NCOR2/TRPM2/SGPL1/EGR1	7
GO:0051926	negative regulation of calcium ion transport	7/1068	68/18722	0.0919445035856054	0.220038153782167	TMBIM6/LILRB1/LILRB2/CD33/SLC30A1/CALM3/GSTO1	7
GO:1900046	regulation of hemostasis	7/1068	68/18722	0.0919445035856054	0.220038153782167	APOE/CD9/CD36/HPSE/PLAU/SH2B3/SERPING1	7
GO:0060048	cardiac muscle contraction	12/1068	137/18722	0.0919750512646299	0.220038153782167	CXCR4/SLC8A1/FLNA/KCNE3/ATP1B1/VEGFB/CALM3/GSTO1/GSN/GAA/RGS2/ATP1A1	12
GO:0003179	heart valve morphogenesis	6/1068	55/18722	0.0920359735148908	0.220038153782167	MEF2C/RB1/TGFB1/TGFBR2/NOTCH2/ROCK1	6
GO:0008333	endosome to lysosome transport	6/1068	55/18722	0.0920359735148908	0.220038153782167	M6PR/DTX3L/ARL8B/RHOB/CHMP3/RAB7A	6
GO:1903321	negative regulation of protein modification by small protein conjugation or removal	9/1068	95/18722	0.0921627551925676	0.220243678927854	TSPO/ISG15/ARRB2/HSPA1A/DTX3L/TNFAIP3/IVNS1ABP/SVBP/CAMLG	9
GO:0031396	regulation of protein ubiquitination	17/1068	210/18722	0.092606489115164	0.221206115655345	LAPTM5/TSPO/ISG15/ARRB2/HSPA1A/DTX3L/LRRK2/GABARAP/TNFAIP3/TGFBR1/UBE2D1/IVNS1ABP/SVBP/HERPUD1/UBE3A/XIAP/CAMLG	17
GO:0030509	BMP signaling pathway	13/1068	152/18722	0.0943990366867776	0.225388142460996	SORL1/SKIL/TGFB1/ENG/NOTCH2/FBXL15/HTRA1/DDX5/UBE2D1/SKI/XIAP/UBE2D3/EGR1	13
GO:0007032	endosome organization	8/1068	82/18722	0.0952745659414431	0.227277434933699	SNX10/CORO1C/STX6/SCARB2/TMEM127/CHMP3/RAB7A/CHMP1B	8
GO:0072527	pyrimidine-containing compound metabolic process	8/1068	82/18722	0.0952745659414431	0.227277434933699	TYMP/UPP1/DPYD/SLC25A19/APOBEC3C/APOBEC3A/MBD4/TK2	8
GO:0042180	cellular ketone metabolic process	17/1068	211/18722	0.0956640505123839	0.228105707717554	APOC1/CD74/FABP5/SLC7A7/PDK4/KYNU/NCOR2/NQO2/LPGAT1/NR1H3/PRKAG2/VKORC1/IL1B/AKR1A1/CPT1A/DHRS4/EGR1	17
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	20/1068	256/18722	0.0959324458799265	0.228543698882156	ZEB2/SORL1/SKIL/SDCBP/HSPA1A/TGFB1/ENG/JAK2/NOTCH2/C20orf27/SPRED1/LRP1/FBXL15/HTRA1/TGFBR1/ADAM17/UBE2D1/SKI/XIAP/UBE2D3	20
GO:1901293	nucleoside phosphate biosynthetic process	20/1068	256/18722	0.0959324458799265	0.228543698882156	TMSB4X/TREM2/PPT1/UPP1/PDK4/PARP9/KYNU/TGFB1/ATP6V1A/NAMPT/IMPDH1/PRKAG2/ACSL1/PAPSS1/HPRT1/STAT3/ACAT1/ADCY7/TK2/ACSL4	20
GO:0060047	heart contraction	19/1068	241/18722	0.0960579989304991	0.228680537204266	GPX1/CXCR4/MEF2A/SLC8A1/FLNA/CELF2/HBEGF/ADORA3/KCNE3/JAK2/ATP1B1/VEGFB/CALM3/GSTO1/GSN/GAA/CDC42/RGS2/ATP1A1	19
GO:0055088	lipid homeostasis	14/1068	167/18722	0.0961805609611772	0.228680537204266	APOE/NPC2/TREM2/IL18/SOAT1/LPL/USF2/NR1H3/ABCG1/ABCA1/RTN4/CEBPA/COMMD9/CNBP	14
GO:0001709	cell fate determination	5/1068	43/18722	0.0964136809006125	0.228680537204266	MEF2C/KLF4/NOTCH2/MCL1/CDC42	5
GO:0006458	'de novo' protein folding	5/1068	43/18722	0.0964136809006125	0.228680537204266	CD74/HSPA1A/ERO1A/HSPH1/SDF2L1	5
GO:0010171	body morphogenesis	5/1068	43/18722	0.0964136809006125	0.228680537204266	ATP6AP2/MMP2/RRAS/SGPL1/SKI	5
GO:0045981	positive regulation of nucleotide metabolic process	5/1068	43/18722	0.0964136809006125	0.228680537204266	TMSB4X/TREM2/HIF1A/P2RX7/STAT3	5
GO:0071604	transforming growth factor beta production	5/1068	43/18722	0.0964136809006125	0.228680537204266	TYROBP/LGALS9/HIF1A/ATP6AP2/LILRB1	5
GO:1900544	positive regulation of purine nucleotide metabolic process	5/1068	43/18722	0.0964136809006125	0.228680537204266	TMSB4X/TREM2/HIF1A/P2RX7/STAT3	5
GO:1901381	positive regulation of potassium ion transmembrane transport	5/1068	43/18722	0.0964136809006125	0.228680537204266	TREM2/FLNA/ATP1B1/WNK1/ATP1B3	5
GO:1904591	positive regulation of protein import	5/1068	43/18722	0.0964136809006125	0.228680537204266	FLNA/TGFB1/JAK2/HCLS1/PIK3R1	5
GO:0055017	cardiac muscle tissue growth	9/1068	96/18722	0.0968458837017102	0.229503903581216	HAMP/MEF2C/TGFBR2/RUNX1/PRKAR1A/TGFBR1/PAK1/AKAP13/RGS2	9
GO:1901655	cellular response to ketone	9/1068	96/18722	0.0968458837017102	0.229503903581216	SPP1/MSN/AHR/PTGER4/KLF4/DDIT4/KLF2/GNB1/NR3C1	9
GO:0009063	cellular amino acid catabolic process	10/1068	110/18722	0.0972329326762293	0.230174293838842	GLUL/SDS/HNMT/IL4I1/DDAH2/SDSL/KYNU/GLS/ACAT1/FAH	10
GO:0009145	purine nucleoside triphosphate biosynthetic process	7/1068	69/18722	0.0975750845353897	0.230174293838842	TMSB4X/TREM2/TGFB1/ATP6V1A/IMPDH1/PRKAG2/STAT3	7
GO:0010611	regulation of cardiac muscle hypertrophy	7/1068	69/18722	0.0975750845353897	0.230174293838842	HAMP/MEF2A/TNFRSF1B/TNFRSF1A/ROCK1/PAK1/RGS2	7
GO:0034605	cellular response to heat	7/1068	69/18722	0.0975750845353897	0.230174293838842	HMOX1/TFEC/LYN/HSPA1A/IRAK1/CDKN1A/ATM	7
GO:0050805	negative regulation of synaptic transmission	7/1068	69/18722	0.0975750845353897	0.230174293838842	GNAI2/RAP1A/LILRB2/LRRK2/PTK2B/SLC30A1/IL1B	7
GO:0021988	olfactory lobe development	4/1068	31/18722	0.0977259650083	0.230174293838842	ID2/ATF5/LRRK2/SKI	4
GO:0030212	hyaluronan metabolic process	4/1068	31/18722	0.0977259650083	0.230174293838842	CD44/HGF/TGFB1/IL1B	4
GO:0031114	regulation of microtubule depolymerization	4/1068	31/18722	0.0977259650083	0.230174293838842	CIB1/ARHGEF2/APC/TAOK1	4
GO:0044819	mitotic G1/S transition checkpoint signaling	4/1068	31/18722	0.0977259650083	0.230174293838842	PLK3/CDKN1A/RPS27L/ATM	4
GO:0060148	positive regulation of posttranscriptional gene silencing	4/1068	31/18722	0.0977259650083	0.230174293838842	ZFP36/TGFB1/STAT3/DDX5	4
GO:0060390	regulation of SMAD protein signal transduction	4/1068	31/18722	0.0977259650083	0.230174293838842	TGFB1/JAK2/LRP1/TGFBR1	4
GO:0070528	protein kinase C signaling	4/1068	31/18722	0.0977259650083	0.230174293838842	PLEK/VEGFA/MYADM/FLOT1	4
GO:0071480	cellular response to gamma radiation	4/1068	31/18722	0.0977259650083	0.230174293838842	CYBA/CDKN1A/ATM/EGR1	4
GO:2000144	positive regulation of DNA-templated transcription, initiation	4/1068	31/18722	0.0977259650083	0.230174293838842	JUN/MITF/ERCC1/SETX	4
GO:0010518	positive regulation of phospholipase activity	6/1068	56/18722	0.0983858856650155	0.231526488900316	C5AR1/CD86/PTAFR/GNA15/GNA13/GNAQ	6
GO:0055078	sodium ion homeostasis	6/1068	56/18722	0.0983858856650155	0.231526488900316	SLC8A1/GNAI2/ATP1B1/SLC1A3/ATP1B3/ATP1A1	6
GO:0045137	development of primary sexual characteristics	18/1068	227/18722	0.0989976637873478	0.232864600608774	NUPR1/LHFPL2/ARRB2/FLNA/RETN/MGST1/VEGFA/TNFSF10/ERCC1/SGPL1/FNDC3A/CEBPB/ARID4A/TGFBR1/UBE3A/BAX/HSD17B4/RAB13	18
GO:0015849	organic acid transport	23/1068	303/18722	0.0998234561704098	0.23470473616363	APOE/FABP5/PLIN2/SLC11A1/SLC7A7/CD36/SLCO2B1/SLC16A3/SYK/SLC38A6/AQP9/ABCC3/LRRC8C/MPC1/SLC6A6/SFXN3/ACSL1/MFSD12/IL1B/CPT1A/SLC1A3/ACSL4/RGS2	23
GO:0051899	membrane depolarization	8/1068	83/18722	0.100472529626235	0.236127948546675	TSPO/YWHAH/SLC8A1/JUN/CASP1/P2RX7/LRRK2/PPP2R3C	8
GO:0006091	generation of precursor metabolites and energy	35/1068	490/18722	0.100814730354324	0.23682903134172	CYBA/NUPR1/FBP1/ALDH2/CYBB/NCF2/CHCHD10/HIF1A/ME2/RHOA/P2RX7/DDIT4/GNPDA1/NCF1/BID/NQO2/CYB5R4/BLOC1S1/PRKAG2/SCO2/IFNAR1/ADPGK/AKR1A1/STAT3/ACAT1/DHRS3/LDHA/PGK1/CEBPA/OXA1L/PKM/GAA/PGLS/PLEC/PPIF	35
GO:0018210	peptidyl-threonine modification	11/1068	125/18722	0.100991365050918	0.237037584086453	TGFB1/DDIT4/TGFBR2/SPRED1/LRRK2/PRKAG2/CALM3/TGFBR1/CAB39/ROCK1/WNK1	11
GO:0055007	cardiac muscle cell differentiation	11/1068	125/18722	0.100991365050918	0.237037584086453	HAMP/MEF2A/SLC8A1/MEF2C/ARRB2/VEGFA/TGFB1/PAK1/AKAP13/RGS2/PLEC	11
GO:0035335	peptidyl-tyrosine dephosphorylation	9/1068	97/18722	0.10166428135817	0.238513244438558	DUSP1/PTPRC/DUSP23/PTPN6/PTPN18/PTPRJ/MTMR6/PTP4A2/DUSP3	9
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	3/1068	20/18722	0.102457831532544	0.238920682346417	ID2/RB1/BACH1	3
GO:0006525	arginine metabolic process	3/1068	20/18722	0.102457831532544	0.238920682346417	SLC7A7/DDAH2/FAH	3
GO:0006607	NLS-bearing protein import into nucleus	3/1068	20/18722	0.102457831532544	0.238920682346417	KPNA3/RANBP2/KPNB1	3
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	3/1068	20/18722	0.102457831532544	0.238920682346417	TYMP/UPP1/DPYD	3
GO:0010523	negative regulation of calcium ion transport into cytosol	3/1068	20/18722	0.102457831532544	0.238920682346417	TMBIM6/CALM3/GSTO1	3
GO:0010801	negative regulation of peptidyl-threonine phosphorylation	3/1068	20/18722	0.102457831532544	0.238920682346417	DDIT4/SPRED1/CALM3	3
GO:0016553	base conversion or substitution editing	3/1068	20/18722	0.102457831532544	0.238920682346417	APOBEC3C/APOBEC3A/ADAR	3
GO:0043691	reverse cholesterol transport	3/1068	20/18722	0.102457831532544	0.238920682346417	APOE/ABCG1/ABCA1	3
GO:0046485	ether lipid metabolic process	3/1068	20/18722	0.102457831532544	0.238920682346417	PLA2G7/LPCAT2/NCEH1	3
GO:0046931	pore complex assembly	3/1068	20/18722	0.102457831532544	0.238920682346417	P2RX7/RTN4/ADAM10	3
GO:0051900	regulation of mitochondrial depolarization	3/1068	20/18722	0.102457831532544	0.238920682346417	TSPO/LRRK2/PPP2R3C	3
GO:0060252	positive regulation of glial cell proliferation	3/1068	20/18722	0.102457831532544	0.238920682346417	TSPO/LYN/IL1B	3
GO:1902004	positive regulation of amyloid-beta formation	3/1068	20/18722	0.102457831532544	0.238920682346417	IFNGR1/ABCG1/PICALM	3
GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	3/1068	20/18722	0.102457831532544	0.238920682346417	GPX1/SOD2/HIF1A	3
GO:0009262	deoxyribonucleotide metabolic process	5/1068	44/18722	0.103951347112083	0.241880754211643	TYMP/SAMHD1/UPP1/DPYD/MBD4	5
GO:0030521	androgen receptor signaling pathway	5/1068	44/18722	0.103951347112083	0.241880754211643	RHOA/ZMIZ1/NCOR2/DDX5/UBE3A	5
GO:0044058	regulation of digestive system process	5/1068	44/18722	0.103951347112083	0.241880754211643	TYMP/HAMP/SGK1/NR1H3/WNK1	5
GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	5/1068	44/18722	0.103951347112083	0.241880754211643	CD300A/IL10RA/JAK2/IL6R/PTK2B	5
GO:0060324	face development	5/1068	44/18722	0.103951347112083	0.241880754211643	MMP2/RRAS/SGPL1/SKI/ZFAND5	5
GO:0006611	protein export from nucleus	6/1068	57/18722	0.104961641307008	0.243916027774597	IFI27/NUP214/SP100/TGFB1/IL1B/UHMK1	6
GO:0006754	ATP biosynthetic process	6/1068	57/18722	0.104961641307008	0.243916027774597	TMSB4X/TREM2/TGFB1/ATP6V1A/PRKAG2/STAT3	6
GO:0097120	receptor localization to synapse	6/1068	57/18722	0.104961641307008	0.243916027774597	TYROBP/RAP1A/ADAM10/STX7/RAB8A/KIF5B	6
GO:0006665	sphingolipid metabolic process	13/1068	155/18722	0.105714093878917	0.244007586692688	PSAP/ASAH1/PPT1/ST8SIA4/GALC/SGPL1/HACD4/HEXA/SERINC1/PLA2G15/ACER3/BAX/GM2A	13
GO:0043502	regulation of muscle adaptation	9/1068	98/18722	0.106617197369715	0.244007586692688	AIF1/HAMP/MEF2A/TNFRSF1B/KLF4/TNFRSF1A/ROCK1/PAK1/RGS2	9
GO:1904029	regulation of cyclin-dependent protein kinase activity	9/1068	98/18722	0.106617197369715	0.244007586692688	ACTB/CDKN1A/TNFAIP3/RGCC/ADAM17/APC/CEBPA/CCNL1/CCNI	9
GO:0006644	phospholipid metabolic process	28/1068	383/18722	0.106891979694751	0.244007586692688	APOC1/FABP5/PLEK/CSF1R/PLA2G7/GPCPD1/LPL/PLSCR1/LPCAT2/AGPAT2/LPGAT1/NR1H3/PLBD2/INPP5D/SRD5A3/OSBPL8/GPX4/SOCS3/MTMR6/ABHD12/EFR3A/ATM/CEPT1/SERINC1/PLA2G15/PLBD1/PIK3R1/SOCS6	28
GO:0006026	aminoglycan catabolic process	4/1068	32/18722	0.106911750704674	0.244007586692688	CD44/TGFB1/IDS/GNS	4
GO:0007435	salivary gland morphogenesis	4/1068	32/18722	0.106911750704674	0.244007586692688	HGF/PLXND1/TGFB1/CDC42	4
GO:0010644	cell communication by electrical coupling	4/1068	32/18722	0.106911750704674	0.244007586692688	SLC8A1/ATP1B1/CALM3/ATP1A1	4
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	4/1068	32/18722	0.106911750704674	0.244007586692688	ZEB2/SDCBP/C20orf27/ADAM17	4
GO:0033687	osteoblast proliferation	4/1068	32/18722	0.106911750704674	0.244007586692688	JUNB/RHOA/HPSE/EIF2AK2	4
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	4/1068	32/18722	0.106911750704674	0.244007586692688	CDKN1A/TNFAIP3/APC/CEBPA	4
GO:0060317	cardiac epithelial to mesenchymal transition	4/1068	32/18722	0.106911750704674	0.244007586692688	ENG/TGFBR2/TGFBR1/RTN4	4
GO:0072525	pyridine-containing compound biosynthetic process	4/1068	32/18722	0.106911750704674	0.244007586692688	PARP9/KYNU/NAMPT/PDXK	4
GO:0090140	regulation of mitochondrial fission	4/1068	32/18722	0.106911750704674	0.244007586692688	STAT2/LRRK2/RALA/DDHD1	4
GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	4/1068	32/18722	0.106911750704674	0.244007586692688	ZEB2/SDCBP/C20orf27/ADAM17	4
GO:0008584	male gonad development	12/1068	141/18722	0.107857191695714	0.244007586692688	NUPR1/FLNA/MGST1/TNFSF10/ERCC1/SGPL1/FNDC3A/ARID4A/TGFBR1/BAX/HSD17B4/RAB13	12
GO:0006650	glycerophospholipid metabolic process	23/1068	306/18722	0.107928144523323	0.244007586692688	APOC1/FABP5/PLEK/CSF1R/PLA2G7/GPCPD1/PLSCR1/LPCAT2/AGPAT2/LPGAT1/NR1H3/INPP5D/OSBPL8/SOCS3/MTMR6/ABHD12/EFR3A/ATM/CEPT1/SERINC1/PLA2G15/PIK3R1/SOCS6	23
GO:0009914	hormone transport	23/1068	306/18722	0.107928144523323	0.244007586692688	SPP1/HLA-DRB1/GLUL/HIF1A/LYN/UCP2/RETN/ALOX5/TCIRG1/BTK/JAK2/CYB5R4/TRPM2/RAB8B/IL1B/SERP1/RAC1/ABCG1/LRP1/CPT1A/STX4/ACSL4/KIF5B	23
GO:0001553	luteinization	2/1068	10/18722	0.107940346448378	0.244007586692688	RETN/SGPL1	2
GO:0001820	serotonin secretion	2/1068	10/18722	0.107940346448378	0.244007586692688	SYK/LILRB1	2
GO:0001865	NK T cell differentiation	2/1068	10/18722	0.107940346448378	0.244007586692688	TGFBR2/PRDM1	2
GO:0002002	regulation of angiotensin levels in blood	2/1068	10/18722	0.107940346448378	0.244007586692688	CTSZ/ATP6AP2	2
GO:0002003	angiotensin maturation	2/1068	10/18722	0.107940346448378	0.244007586692688	CTSZ/ATP6AP2	2
GO:0002084	protein depalmitoylation	2/1068	10/18722	0.107940346448378	0.244007586692688	PPT1/ABHD12	2
GO:0003056	regulation of vascular associated smooth muscle contraction	2/1068	10/18722	0.107940346448378	0.244007586692688	DOCK4/RHOA	2
GO:0005984	disaccharide metabolic process	2/1068	10/18722	0.107940346448378	0.244007586692688	FBP1/GAA	2
GO:0010728	regulation of hydrogen peroxide biosynthetic process	2/1068	10/18722	0.107940346448378	0.244007586692688	SOD2/STAT3	2
GO:0010968	regulation of microtubule nucleation	2/1068	10/18722	0.107940346448378	0.244007586692688	HSPA1A/PAK1	2
GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation	2/1068	10/18722	0.107940346448378	0.244007586692688	EIF2AK2/DNAJC3	2
GO:0015911	long-chain fatty acid import across plasma membrane	2/1068	10/18722	0.107940346448378	0.244007586692688	CD36/ACSL1	2
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	2/1068	10/18722	0.107940346448378	0.244007586692688	P4HA1/ERO1A	2
GO:0030214	hyaluronan catabolic process	2/1068	10/18722	0.107940346448378	0.244007586692688	CD44/TGFB1	2
GO:0032253	dense core granule localization	2/1068	10/18722	0.107940346448378	0.244007586692688	TANC2/KIF5B	2
GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway	2/1068	10/18722	0.107940346448378	0.244007586692688	PARP9/NAMPT	2
GO:0034756	regulation of iron ion transport	2/1068	10/18722	0.107940346448378	0.244007586692688	B2M/HAMP	2
GO:0035376	sterol import	2/1068	10/18722	0.107940346448378	0.244007586692688	CD36/LRP1	2
GO:0035646	endosome to melanosome transport	2/1068	10/18722	0.107940346448378	0.244007586692688	CD63/RAB32	2
GO:0035747	natural killer cell chemotaxis	2/1068	10/18722	0.107940346448378	0.244007586692688	CCL3/CCL4	2
GO:0042996	regulation of Golgi to plasma membrane protein transport	2/1068	10/18722	0.107940346448378	0.244007586692688	CSK/ATP2C1	2
GO:0043485	endosome to pigment granule transport	2/1068	10/18722	0.107940346448378	0.244007586692688	CD63/RAB32	2
GO:0044557	relaxation of smooth muscle	2/1068	10/18722	0.107940346448378	0.244007586692688	SLC8A1/RGS2	2
GO:0048755	branching morphogenesis of a nerve	2/1068	10/18722	0.107940346448378	0.244007586692688	LRRK2/RTN4	2
GO:0048757	pigment granule maturation	2/1068	10/18722	0.107940346448378	0.244007586692688	CD63/RAB32	2
GO:0050861	positive regulation of B cell receptor signaling pathway	2/1068	10/18722	0.107940346448378	0.244007586692688	CD81/CMTM3	2
GO:0060068	vagina development	2/1068	10/18722	0.107940346448378	0.244007586692688	AXL/BAX	2
GO:0060736	prostate gland growth	2/1068	10/18722	0.107940346448378	0.244007586692688	PSAP/UBE3A	2
GO:0070383	DNA cytosine deamination	2/1068	10/18722	0.107940346448378	0.244007586692688	APOBEC3C/APOBEC3A	2
GO:0070508	cholesterol import	2/1068	10/18722	0.107940346448378	0.244007586692688	CD36/LRP1	2
GO:0071233	cellular response to leucine	2/1068	10/18722	0.107940346448378	0.244007586692688	RRAGD/SESN3	2
GO:0072124	regulation of glomerular mesangial cell proliferation	2/1068	10/18722	0.107940346448378	0.244007586692688	IL6R/EGR1	2
GO:0072203	cell proliferation involved in metanephros development	2/1068	10/18722	0.107940346448378	0.244007586692688	STAT1/EGR1	2
GO:0090209	negative regulation of triglyceride metabolic process	2/1068	10/18722	0.107940346448378	0.244007586692688	APOE/SORL1	2
GO:0090527	actin filament reorganization	2/1068	10/18722	0.107940346448378	0.244007586692688	ARAP1/GSN	2
GO:0097084	vascular associated smooth muscle cell development	2/1068	10/18722	0.107940346448378	0.244007586692688	VEGFA/ENG	2
GO:0098903	regulation of membrane repolarization during action potential	2/1068	10/18722	0.107940346448378	0.244007586692688	FLNA/KCNE3	2
GO:0099519	dense core granule cytoskeletal transport	2/1068	10/18722	0.107940346448378	0.244007586692688	TANC2/KIF5B	2
GO:0099532	synaptic vesicle endosomal processing	2/1068	10/18722	0.107940346448378	0.244007586692688	STX6/ITSN2	2
GO:1901203	positive regulation of extracellular matrix assembly	2/1068	10/18722	0.107940346448378	0.244007586692688	TGFB1/RGCC	2
GO:1901725	regulation of histone deacetylase activity	2/1068	10/18722	0.107940346448378	0.244007586692688	VEGFA/LRRK2	2
GO:1901950	dense core granule transport	2/1068	10/18722	0.107940346448378	0.244007586692688	TANC2/KIF5B	2
GO:1904350	regulation of protein catabolic process in the vacuole	2/1068	10/18722	0.107940346448378	0.244007586692688	CD81/LRP1	2
GO:1904779	regulation of protein localization to centrosome	2/1068	10/18722	0.107940346448378	0.244007586692688	APC/NUP62	2
GO:1990253	cellular response to leucine starvation	2/1068	10/18722	0.107940346448378	0.244007586692688	RRAGD/SESN3	2
GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin	2/1068	10/18722	0.107940346448378	0.244007586692688	VEGFA/RGCC	2
GO:2000510	positive regulation of dendritic cell chemotaxis	2/1068	10/18722	0.107940346448378	0.244007586692688	SPI1/LGALS9	2
GO:2001225	regulation of chloride transport	2/1068	10/18722	0.107940346448378	0.244007586692688	PRNP/PTAFR	2
GO:0050818	regulation of coagulation	7/1068	71/18722	0.109390586771516	0.247182414664615	APOE/CD9/CD36/HPSE/PLAU/SH2B3/SERPING1	7
GO:0051224	negative regulation of protein transport	11/1068	127/18722	0.109682693753695	0.247738725615295	APOE/CD36/UCP2/SP100/MDFIC/RSAD2/CSK/NR1H3/RHBDF2/LRRK2/IL1B	11
GO:0032092	positive regulation of protein binding	8/1068	85/18722	0.111334850090832	0.251260079920589	APOE/B2M/PLXND1/DTX3L/LRRK2/STK4/LRP1/FLOT1	8
GO:0055013	cardiac muscle cell development	8/1068	85/18722	0.111334850090832	0.251260079920589	HAMP/MEF2A/SLC8A1/VEGFA/PAK1/AKAP13/RGS2/PLEC	8
GO:1902115	regulation of organelle assembly	15/1068	186/18722	0.111564195480266	0.251298237820113	NUPR1/CCDC88A/LCP1/MSN/SDCBP/RHOA/HSPA1A/HCK/ABI3/LRRK2/GSN/ATG3/NUP62/SDCCAG8/CHMP1B	15
GO:0010717	regulation of epithelial to mesenchymal transition	9/1068	99/18722	0.111703705241751	0.251298237820113	SDCBP/GLIPR2/TGFB1/ENG/TGFBR2/SPRED1/IL1B/RGCC/TGFBR1	9
GO:0006826	iron ion transport	6/1068	58/18722	0.111759558546453	0.251298237820113	FTL/B2M/FTH1/HAMP/SLC11A1/MCOLN1	6
GO:0007405	neuroblast proliferation	6/1068	58/18722	0.111759558546453	0.251298237820113	HIF1A/VEGFA/LRRK2/ARHGEF2/NUMB/RAB10	6
GO:0035384	thioester biosynthetic process	5/1068	45/18722	0.111770898956314	0.251298237820113	PPT1/PDK4/ACSL1/ACAT1/ACSL4	5
GO:0042551	neuron maturation	5/1068	45/18722	0.111770898956314	0.251298237820113	C3/C1QA/RB1/NR4A2/LRRK2	5
GO:0045933	positive regulation of muscle contraction	5/1068	45/18722	0.111770898956314	0.251298237820113	RHOA/PTAFR/GSTO1/RGS2/ATP1A1	5
GO:0071364	cellular response to epidermal growth factor stimulus	5/1068	45/18722	0.111770898956314	0.251298237820113	ZFP36L2/ZFP36/ZFP36L1/DUSP3/IQGAP1	5
GO:0071616	acyl-CoA biosynthetic process	5/1068	45/18722	0.111770898956314	0.251298237820113	PPT1/PDK4/ACSL1/ACAT1/ACSL4	5
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	11/1068	128/18722	0.114185415670128	0.255664226115251	ZEB2/SKIL/SDCBP/HSPA1A/TGFB1/ENG/C20orf27/SPRED1/HTRA1/ADAM17/SKI	11
GO:0003177	pulmonary valve development	3/1068	21/18722	0.114707763421983	0.255664226115251	TNFRSF1B/NOTCH2/TNFRSF1A	3
GO:0006925	inflammatory cell apoptotic process	3/1068	21/18722	0.114707763421983	0.255664226115251	MEF2C/PLEKHO2/IRF7	3
GO:0032288	myelin assembly	3/1068	21/18722	0.114707763421983	0.255664226115251	CD9/TLR2/PMP22	3
GO:0035020	regulation of Rac protein signal transduction	3/1068	21/18722	0.114707763421983	0.255664226115251	GABARAP/ARHGAP24/ARF6	3
GO:0038083	peptidyl-tyrosine autophosphorylation	3/1068	21/18722	0.114707763421983	0.255664226115251	VEGFA/PTK2B/IQGAP1	3
GO:0042454	ribonucleoside catabolic process	3/1068	21/18722	0.114707763421983	0.255664226115251	UPP1/APOBEC3C/APOBEC3A	3
GO:0043576	regulation of respiratory gaseous exchange	3/1068	21/18722	0.114707763421983	0.255664226115251	NR4A2/GLS/PBX3	3
GO:0046597	negative regulation of viral entry into host cell	3/1068	21/18722	0.114707763421983	0.255664226115251	IFITM3/CIITA/GSN	3
GO:0046823	negative regulation of nucleocytoplasmic transport	3/1068	21/18722	0.114707763421983	0.255664226115251	CD36/SP100/MDFIC	3
GO:0046885	regulation of hormone biosynthetic process	3/1068	21/18722	0.114707763421983	0.255664226115251	HIF1A/EGR1/ATP1A1	3
GO:0048714	positive regulation of oligodendrocyte differentiation	3/1068	21/18722	0.114707763421983	0.255664226115251	CXCR4/TLR2/TNFRSF1B	3
GO:0050849	negative regulation of calcium-mediated signaling	3/1068	21/18722	0.114707763421983	0.255664226115251	PLEK/HOMER3/PRNP	3
GO:0051152	positive regulation of smooth muscle cell differentiation	3/1068	21/18722	0.114707763421983	0.255664226115251	SOD2/ENG/PIAS1	3
GO:0070269	pyroptosis	3/1068	21/18722	0.114707763421983	0.255664226115251	TREM2/NAIP/CASP1	3
GO:0072111	cell proliferation involved in kidney development	3/1068	21/18722	0.114707763421983	0.255664226115251	STAT1/IL6R/EGR1	3
GO:0097062	dendritic spine maintenance	3/1068	21/18722	0.114707763421983	0.255664226115251	APOE/TREM2/PRNP	3
GO:0099515	actin filament-based transport	3/1068	21/18722	0.114707763421983	0.255664226115251	MYO5A/MYO1F/MYO1G	3
GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	3/1068	21/18722	0.114707763421983	0.255664226115251	CD74/CD44/ZNF385A	3
GO:1905209	positive regulation of cardiocyte differentiation	3/1068	21/18722	0.114707763421983	0.255664226115251	MEF2C/ARRB2/TGFB1	3
GO:2000047	regulation of cell-cell adhesion mediated by cadherin	3/1068	21/18722	0.114707763421983	0.255664226115251	VEGFA/RGCC/FLOT1	3
GO:0061136	regulation of proteasomal protein catabolic process	15/1068	187/18722	0.115276131231652	0.256824939771261	APOE/GPX1/TREM2/NUPR1/SDCBP/HSPA1A/PLK3/LRRK2/GABARAP/CEBPA/HERPUD1/PIAS1/PSME2/CAMLG/SUMO2	15
GO:0014743	regulation of muscle hypertrophy	7/1068	72/18722	0.115571037824728	0.257163430969992	HAMP/MEF2A/TNFRSF1B/TNFRSF1A/ROCK1/PAK1/RGS2	7
GO:0042246	tissue regeneration	7/1068	72/18722	0.115571037824728	0.257163430969992	GPX1/CD9/CD81/TGFBR2/RUNX1/CDKN1A/NINJ1	7
GO:0055021	regulation of cardiac muscle tissue growth	7/1068	72/18722	0.115571037824728	0.257163430969992	HAMP/MEF2C/TGFBR2/RUNX1/TGFBR1/PAK1/RGS2	7
GO:0046660	female sex differentiation	10/1068	114/18722	0.115876203238547	0.257417864419597	NUPR1/LHFPL2/ARRB2/RETN/AXL/VEGFA/SGPL1/CEBPB/UBE3A/BAX	10
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	10/1068	114/18722	0.115876203238547	0.257417864419597	ZEB2/SDCBP/TGFB1/ENG/JAK2/NOTCH2/C20orf27/FBXL15/TGFBR1/ADAM17	10
GO:1901800	positive regulation of proteasomal protein catabolic process	10/1068	114/18722	0.115876203238547	0.257417864419597	TREM2/NUPR1/HSPA1A/PLK3/LRRK2/GABARAP/CEBPA/HERPUD1/PIAS1/SUMO2	10
GO:1904892	regulation of receptor signaling pathway via STAT	10/1068	114/18722	0.115876203238547	0.257417864419597	PTPRC/CD300A/IL10RA/TGFB1/JAK2/IL6R/SH2B3/PTK2B/PARP14/SOCS3	10
GO:0034763	negative regulation of transmembrane transport	12/1068	143/18722	0.116366200241193	0.257783513341388	FABP5/HAMP/PEA15/OAZ1/KCNE3/SLC30A1/IL1B/CALM3/CAB39/GSTO1/RGS2/PPIF	12
GO:0062013	positive regulation of small molecule metabolic process	12/1068	143/18722	0.116366200241193	0.257783513341388	CD74/TMSB4X/TREM2/HIF1A/P2RX7/PTAFR/LPGAT1/NR1H3/IL1B/STAT3/ABCG1/CPT1A	12
GO:0010165	response to X-ray	4/1068	33/18722	0.11647075713979	0.257783513341388	HAMP/CDKN1A/ERCC1/ATM	4
GO:0035025	positive regulation of Rho protein signal transduction	4/1068	33/18722	0.11647075713979	0.257783513341388	GPR65/LPAR6/RAC1/AKAP13	4
GO:0071353	cellular response to interleukin-4	4/1068	33/18722	0.11647075713979	0.257783513341388	CORO1A/CD300LF/STAT6/PARP14	4
GO:0071539	protein localization to centrosome	4/1068	33/18722	0.11647075713979	0.257783513341388	SNX10/APC/NUP62/CEP350	4
GO:1903146	regulation of autophagy of mitochondrion	4/1068	33/18722	0.11647075713979	0.257783513341388	TSPO/HIF1A/VPS13C/BNIP3L	4
GO:1903715	regulation of aerobic respiration	4/1068	33/18722	0.11647075713979	0.257783513341388	NUPR1/HIF1A/RHOA/PPIF	4
GO:1904030	negative regulation of cyclin-dependent protein kinase activity	4/1068	33/18722	0.11647075713979	0.257783513341388	CDKN1A/TNFAIP3/APC/CEBPA	4
GO:0042391	regulation of membrane potential	31/1068	434/18722	0.116635247226553	0.258041735971497	TREM2/TSPO/SOD2/YWHAH/SLC8A1/CHCHD10/JUN/CD36/MEF2C/ARRB2/FLNA/UCP2/CASP1/P2RX7/KCNAB2/BID/KCNE3/ATP1B1/GNA15/LRRK2/GLRX/BNIP3L/PTK2B/CALM3/PPP2R3C/CLIC1/GNAQ/BAX/KIF5B/ATP1B3/ATP1A1	31
GO:0046545	development of primary female sexual characteristics	9/1068	100/18722	0.116922705380525	0.258465759210699	NUPR1/LHFPL2/ARRB2/RETN/VEGFA/SGPL1/CEBPB/UBE3A/BAX	9
GO:0060840	artery development	9/1068	100/18722	0.116922705380525	0.258465759210699	APOE/ZMIZ1/VEGFA/PLXND1/ENG/PRDM1/CNTRL/LRP1/TGFBR1	9
GO:1903510	mucopolysaccharide metabolic process	8/1068	86/18722	0.116996214144687	0.258522347061725	CD44/DSE/HGF/TGFB1/CSGALNACT2/GNS/IL1B/B3GNT2	8
GO:0060562	epithelial tube morphogenesis	24/1068	325/18722	0.11793633122692	0.260493018133632	CTSZ/CXCR4/CTSH/CSF1R/HIF1A/MEF2C/RHOA/ITGAX/VEGFA/ST14/PLXND1/TGFB1/ENG/TGFBR2/NOTCH2/VASP/STK4/PRKX/RALA/PRKACB/PAK1/SKI/RHOB/PFN1	24
GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	18/1068	233/18722	0.118333373413709	0.261263045392952	PSAP/RGS1/GPR65/GNAI2/FLNA/MARCO/FPR1/PTGER4/ADGRE2/GNA15/GNA13/ADCY7/ABCA1/PRKACB/GNB1/GNAQ/AKAP13/RGS2	18
GO:0000910	cytokinesis	14/1068	173/18722	0.118661496440023	0.261740304698961	ACTR2/ACTR3/RHOA/KLHDC8B/PLK3/CALM3/ROCK1/APC/NUP62/RHOB/CDC42/CHMP3/PLEC/CHMP1B	14
GO:0006767	water-soluble vitamin metabolic process	6/1068	59/18722	0.118775489201398	0.261740304698961	SLC25A19/SLC2A3/PDXK/AKR1A1/MTHFD2/GSTO1	6
GO:0019369	arachidonic acid metabolic process	6/1068	59/18722	0.118775489201398	0.261740304698961	GPX1/ALOX5/TBXAS1/PTGS1/GPX4/ABHD12	6
GO:0021885	forebrain cell migration	6/1068	59/18722	0.118775489201398	0.261740304698961	CXCR4/RHOA/AXL/ZMIZ1/LRRK2/RTN4	6
GO:0006022	aminoglycan metabolic process	11/1068	129/18722	0.118792069349102	0.261740304698961	CD44/DSE/HGF/HS3ST1/TGFB1/CSGALNACT2/IDS/GNS/IL1B/HEXA/B3GNT2	11
GO:0030308	negative regulation of cell growth	15/1068	188/18722	0.119060508973706	0.262190669919989	SPP1/BST2/FBP1/PPT1/RB1/HSPA1A/TGFB1/BCL6/ARHGAP4/CDKN1A/PTPRJ/BTG1/RTN4/PAK1/RGS2	15
GO:0006643	membrane lipid metabolic process	16/1068	203/18722	0.119093649365066	0.262190669919989	PSAP/ASAH1/PPT1/GAL3ST4/ST8SIA4/GALC/SCCPDH/MGST2/SGPL1/HACD4/HEXA/SERINC1/PLA2G15/ACER3/BAX/GM2A	16
GO:0044818	mitotic G2/M transition checkpoint	5/1068	46/18722	0.119864865290665	0.263673384879098	TAOK3/CDKN1A/ATM/FOXN3/TAOK1	5
GO:1900271	regulation of long-term synaptic potentiation	5/1068	46/18722	0.119864865290665	0.263673384879098	APOE/TYROBP/LGMN/PRNP/LILRB2	5
GO:1901988	negative regulation of cell cycle phase transition	19/1068	249/18722	0.120945813173069	0.265942790497914	GPNMB/ZFP36L2/DUSP1/ZFP36L1/RB1/TAOK3/ATF5/KLF4/PLK3/SLFN11/CDKN1A/RNASEH2B/RPS27L/RGCC/ATM/FOXN3/APC/DYNC1LI1/TAOK1	19
GO:0060560	developmental growth involved in morphogenesis	18/1068	234/18722	0.121762297166206	0.267629065380387	APOE/SPP1/CXCR4/ALCAM/DPYSL2/TWF2/VEGFA/TGFBR2/ITGA4/ARHGAP4/ITSN2/CYFIP1/SHTN1/LRP1/IQGAP1/RTN4/PAK1/DBNL	18
GO:0051865	protein autoubiquitination	7/1068	73/18722	0.121929777492772	0.267779031074886	RNF213/RNF13/DTX3L/LRRK2/KLHL24/UBE3A/UBE2D3	7
GO:0099518	vesicle cytoskeletal trafficking	7/1068	73/18722	0.121929777492772	0.267779031074886	MYO5A/MYO1F/TANC2/MYO1G/BLOC1S1/BLOC1S2/KIF5B	7
GO:1903169	regulation of calcium ion transmembrane transport	13/1068	159/18722	0.122004735362959	0.267816325999989	CYBA/SLC8A1/LYN/VMP1/CORO1A/PRNP/KCNE3/PTPN6/ATP1B1/PTK2B/CALM3/GSTO1/BAX	13
GO:0003012	muscle system process	32/1068	452/18722	0.122046024024087	0.267816325999989	CYBA/AIF1/HAMP/CXCR4/MEF2A/HMOX1/SLC8A1/DOCK4/FLNA/TPM3/RHOA/TNFRSF1B/KLF4/PTAFR/KCNE3/RCSD1/ATP1B1/SCO2/IL1B/VEGFB/CALM3/TNFRSF1A/ROCK1/GSTO1/GSN/PAK1/NR4A1/GAA/AKAP13/RGS2/MYL6/ATP1A1	32
GO:0048639	positive regulation of developmental growth	14/1068	174/18722	0.122683297803191	0.269105315018707	HAMP/CXCR4/MEF2C/TWF2/VEGFA/TGFBR2/SASH3/ITSN2/CYFIP1/SERP1/SHTN1/LRP1/PAK1/DBNL	14
GO:1901987	regulation of cell cycle phase transition	28/1068	390/18722	0.124922514614743	0.27188185140266	GPNMB/AIF1/ZFP36L2/DUSP1/ID2/ZFP36L1/RB1/TAOK3/ATF5/KLF4/BID/PTPN6/PLK3/SLFN11/CDKN1A/KMT2E/RNASEH2B/RPS27L/RGCC/ATM/FOXN3/ADAM17/APC/DYNC1LI1/TAOK1/RCC2/PSME2/APPL1	28
GO:0006893	Golgi to plasma membrane transport	6/1068	60/18722	0.126004842121915	0.27188185140266	VAMP5/GGA2/CSK/ATP2C1/GGA1/RAB10	6
GO:0033866	nucleoside bisphosphate biosynthetic process	6/1068	60/18722	0.126004842121915	0.27188185140266	PPT1/PDK4/ACSL1/PAPSS1/ACAT1/ACSL4	6
GO:0034030	ribonucleoside bisphosphate biosynthetic process	6/1068	60/18722	0.126004842121915	0.27188185140266	PPT1/PDK4/ACSL1/PAPSS1/ACAT1/ACSL4	6
GO:0034033	purine nucleoside bisphosphate biosynthetic process	6/1068	60/18722	0.126004842121915	0.27188185140266	PPT1/PDK4/ACSL1/PAPSS1/ACAT1/ACSL4	6
GO:0007431	salivary gland development	4/1068	34/18722	0.126387030737136	0.27188185140266	HGF/PLXND1/TGFB1/CDC42	4
GO:0007616	long-term memory	4/1068	34/18722	0.126387030737136	0.27188185140266	APOE/SGK1/PRNP/PJA2	4
GO:0010614	negative regulation of cardiac muscle hypertrophy	4/1068	34/18722	0.126387030737136	0.27188185140266	TNFRSF1B/TNFRSF1A/PAK1/RGS2	4
GO:0014072	response to isoquinoline alkaloid	4/1068	34/18722	0.126387030737136	0.27188185140266	AIF1/CXCR4/PEA15/FOSB	4
GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	4/1068	34/18722	0.126387030737136	0.27188185140266	CCL3/SLC8A1/CALM3/GSTO1	4
GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	4/1068	34/18722	0.126387030737136	0.27188185140266	IRF7/OAS3/IFIH1/RNF135	4
GO:0043278	response to morphine	4/1068	34/18722	0.126387030737136	0.27188185140266	AIF1/CXCR4/PEA15/FOSB	4
GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	4/1068	34/18722	0.126387030737136	0.27188185140266	GPR65/C3AR1/LPAR6/GNA15	4
GO:0070884	regulation of calcineurin-NFAT signaling cascade	4/1068	34/18722	0.126387030737136	0.27188185140266	CLEC7A/HOMER3/CIB1/PRNP	4
GO:0001765	membrane raft assembly	2/1068	11/18722	0.127119941883597	0.27188185140266	FLOT1/S100A10	2
GO:0001787	natural killer cell proliferation	2/1068	11/18722	0.127119941883597	0.27188185140266	HLA-E/IL18	2
GO:0001867	complement activation, lectin pathway	2/1068	11/18722	0.127119941883597	0.27188185140266	A2M/SERPING1	2
GO:0002725	negative regulation of T cell cytokine production	2/1068	11/18722	0.127119941883597	0.27188185140266	LILRB4/HLA-F	2
GO:0002732	positive regulation of dendritic cell cytokine production	2/1068	11/18722	0.127119941883597	0.27188185140266	CLEC7A/SCIMP	2
GO:0006527	arginine catabolic process	2/1068	11/18722	0.127119941883597	0.27188185140266	DDAH2/FAH	2
GO:0006568	tryptophan metabolic process	2/1068	11/18722	0.127119941883597	0.27188185140266	IL4I1/KYNU	2
GO:0006707	cholesterol catabolic process	2/1068	11/18722	0.127119941883597	0.27188185140266	APOE/CYP27A1	2
GO:0006971	hypotonic response	2/1068	11/18722	0.127119941883597	0.27188185140266	TSPO/CAB39	2
GO:0009120	deoxyribonucleoside metabolic process	2/1068	11/18722	0.127119941883597	0.27188185140266	DPYD/TK2	2
GO:0010269	response to selenium ion	2/1068	11/18722	0.127119941883597	0.27188185140266	GPX1/SOD2	2
GO:0016127	sterol catabolic process	2/1068	11/18722	0.127119941883597	0.27188185140266	APOE/CYP27A1	2
GO:0032957	inositol trisphosphate metabolic process	2/1068	11/18722	0.127119941883597	0.27188185140266	PTAFR/PTK2B	2
GO:0033327	Leydig cell differentiation	2/1068	11/18722	0.127119941883597	0.27188185140266	MGST1/SGPL1	2
GO:0033483	gas homeostasis	2/1068	11/18722	0.127119941883597	0.27188185140266	SOD2/HIF1A	2
GO:0033632	regulation of cell-cell adhesion mediated by integrin	2/1068	11/18722	0.127119941883597	0.27188185140266	FERMT3/WNK1	2
GO:0033860	regulation of NAD(P)H oxidase activity	2/1068	11/18722	0.127119941883597	0.27188185140266	CYBA/GNAI2	2
GO:0034163	regulation of toll-like receptor 9 signaling pathway	2/1068	11/18722	0.127119941883597	0.27188185140266	RSAD2/RTN4	2
GO:0034379	very-low-density lipoprotein particle assembly	2/1068	11/18722	0.127119941883597	0.27188185140266	APOC1/SOAT1	2
GO:0036490	regulation of translation in response to endoplasmic reticulum stress	2/1068	11/18722	0.127119941883597	0.27188185140266	PPP1R15A/DNAJC3	2
GO:0042447	hormone catabolic process	2/1068	11/18722	0.127119941883597	0.27188185140266	SPP1/HSD17B11	2
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	2/1068	11/18722	0.127119941883597	0.27188185140266	HMOX1/HIF1A	2
GO:0046929	negative regulation of neurotransmitter secretion	2/1068	11/18722	0.127119941883597	0.27188185140266	RAP1A/SLC30A1	2
GO:0060312	regulation of blood vessel remodeling	2/1068	11/18722	0.127119941883597	0.27188185140266	CST3/TGFB1	2
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	2/1068	11/18722	0.127119941883597	0.27188185140266	CALM3/GSTO1	2
GO:0070243	regulation of thymocyte apoptotic process	2/1068	11/18722	0.127119941883597	0.27188185140266	HIF1A/ADAM8	2
GO:0070417	cellular response to cold	2/1068	11/18722	0.127119941883597	0.27188185140266	NFKBIA/DNAJC3	2
GO:0070944	neutrophil-mediated killing of bacterium	2/1068	11/18722	0.127119941883597	0.27188185140266	TREM1/MYD88	2
GO:0071492	cellular response to UV-A	2/1068	11/18722	0.127119941883597	0.27188185140266	TIMP1/MMP2	2
GO:0071609	chemokine (C-C motif) ligand 5 production	2/1068	11/18722	0.127119941883597	0.27188185140266	SIRPA/OAS3	2
GO:0071649	regulation of chemokine (C-C motif) ligand 5 production	2/1068	11/18722	0.127119941883597	0.27188185140266	SIRPA/OAS3	2
GO:0072110	glomerular mesangial cell proliferation	2/1068	11/18722	0.127119941883597	0.27188185140266	IL6R/EGR1	2
GO:0075733	intracellular transport of virus	2/1068	11/18722	0.127119941883597	0.27188185140266	BST2/KPNA3	2
GO:0090084	negative regulation of inclusion body assembly	2/1068	11/18722	0.127119941883597	0.27188185140266	SORL1/HSPA1A	2
GO:0090160	Golgi to lysosome transport	2/1068	11/18722	0.127119941883597	0.27188185140266	LAPTM5/LAMP1	2
GO:0106049	regulation of cellular response to osmotic stress	2/1068	11/18722	0.127119941883597	0.27188185140266	ARHGEF2/MICU1	2
GO:1903238	positive regulation of leukocyte tethering or rolling	2/1068	11/18722	0.127119941883597	0.27188185140266	PTAFR/ITGA4	2
GO:1904464	regulation of matrix metallopeptidase secretion	2/1068	11/18722	0.127119941883597	0.27188185140266	TLR2/TLR4	2
GO:1905050	positive regulation of metallopeptidase activity	2/1068	11/18722	0.127119941883597	0.27188185140266	MBP/STAT3	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	2/1068	11/18722	0.127119941883597	0.27188185140266	CEBPB/ATF3	2
GO:1990773	matrix metallopeptidase secretion	2/1068	11/18722	0.127119941883597	0.27188185140266	TLR2/TLR4	2
GO:2000392	regulation of lamellipodium morphogenesis	2/1068	11/18722	0.127119941883597	0.27188185140266	CD44/CORO1C	2
GO:2000480	negative regulation of cAMP-dependent protein kinase activity	2/1068	11/18722	0.127119941883597	0.27188185140266	PRKAG2/PRKAR1A	2
GO:0006662	glycerol ether metabolic process	3/1068	22/18722	0.127476108978638	0.27188185140266	PLA2G7/LPCAT2/NCEH1	3
GO:0010310	regulation of hydrogen peroxide metabolic process	3/1068	22/18722	0.127476108978638	0.27188185140266	SOD2/STAT3/RAC1	3
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	3/1068	22/18722	0.127476108978638	0.27188185140266	SLC8A1/CALM3/GSTO1	3
GO:0032693	negative regulation of interleukin-10 production	3/1068	22/18722	0.127476108978638	0.27188185140266	TYROBP/LILRB4/LILRB1	3
GO:0032700	negative regulation of interleukin-17 production	3/1068	22/18722	0.127476108978638	0.27188185140266	NCKAP1L/TLR4/PRNP	3
GO:0034755	iron ion transmembrane transport	3/1068	22/18722	0.127476108978638	0.27188185140266	HAMP/SLC11A1/MCOLN1	3
GO:0035089	establishment of apical/basal cell polarity	3/1068	22/18722	0.127476108978638	0.27188185140266	MSN/RHOA/CDC42	3
GO:0045048	protein insertion into ER membrane	3/1068	22/18722	0.127476108978638	0.27188185140266	EMC3/TRAM1/CAMLG	3
GO:0045061	thymic T cell selection	3/1068	22/18722	0.127476108978638	0.27188185140266	CD74/PTPRC/DOCK2	3
GO:0045624	positive regulation of T-helper cell differentiation	3/1068	22/18722	0.127476108978638	0.27188185140266	CD86/IL18/NFKBIZ	3
GO:0071359	cellular response to dsRNA	3/1068	22/18722	0.127476108978638	0.27188185140266	IFIT1/IFIH1/FLOT1	3
GO:2000725	regulation of cardiac muscle cell differentiation	3/1068	22/18722	0.127476108978638	0.27188185140266	MEF2C/ARRB2/TGFB1	3
GO:2000773	negative regulation of cellular senescence	3/1068	22/18722	0.127476108978638	0.27188185140266	YBX1/NAMPT/BCL6	3
GO:0001841	neural tube formation	9/1068	102/18722	0.127752936912438	0.27236461777144	HIF1A/ST14/TGFB1/VASP/STK4/RALA/PRKACB/SKI/PFN1	9
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	5/1068	47/18722	0.128225117991047	0.272480587583738	CYBA/CTSZ/SOD2/RHOA/ATP6AP2	5
GO:0009261	ribonucleotide catabolic process	5/1068	47/18722	0.128225117991047	0.272480587583738	UPP1/NUDT3/DPYD/HPRT1/ACAT1	5
GO:0035850	epithelial cell differentiation involved in kidney development	5/1068	47/18722	0.128225117991047	0.272480587583738	STAT1/MEF2C/NOTCH2/PRKX/IQGAP1	5
GO:0042311	vasodilation	5/1068	47/18722	0.128225117991047	0.272480587583738	APOE/GPX1/SOD2/KLF2/RGS2	5
GO:0043114	regulation of vascular permeability	5/1068	47/18722	0.128225117991047	0.272480587583738	APOE/VEGFA/TGFB1/PTPRJ/PLEC	5
GO:0045601	regulation of endothelial cell differentiation	5/1068	47/18722	0.128225117991047	0.272480587583738	VEGFA/IL1B/BTG1/TNFRSF1A/ROCK1	5
GO:0045911	positive regulation of DNA recombination	5/1068	47/18722	0.128225117991047	0.272480587583738	PTPRC/ACTR2/WAS/TGFB1/STAT6	5
GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	11/1068	131/18722	0.128314227193514	0.272480587583738	ZEB2/SKIL/SDCBP/HSPA1A/TGFB1/ENG/C20orf27/SPRED1/HTRA1/ADAM17/SKI	11
GO:1904950	negative regulation of establishment of protein localization	11/1068	131/18722	0.128314227193514	0.272480587583738	APOE/CD36/UCP2/SP100/MDFIC/RSAD2/CSK/NR1H3/RHBDF2/LRRK2/IL1B	11
GO:0003151	outflow tract morphogenesis	7/1068	74/18722	0.128463790736292	0.272480587583738	HIF1A/MEF2C/VEGFA/PLXND1/ENG/TGFBR2/DHRS3	7
GO:0009201	ribonucleoside triphosphate biosynthetic process	7/1068	74/18722	0.128463790736292	0.272480587583738	TMSB4X/TREM2/TGFB1/ATP6V1A/IMPDH1/PRKAG2/STAT3	7
GO:0046470	phosphatidylcholine metabolic process	7/1068	74/18722	0.128463790736292	0.272480587583738	APOC1/FABP5/PLA2G7/LPCAT2/NR1H3/CEPT1/PLA2G15	7
GO:0048844	artery morphogenesis	7/1068	74/18722	0.128463790736292	0.272480587583738	APOE/ZMIZ1/VEGFA/ENG/PRDM1/LRP1/TGFBR1	7
GO:1901657	glycosyl compound metabolic process	8/1068	88/18722	0.128770163875314	0.273023105804005	TYMP/UPP1/DPYD/APOBEC3C/APOBEC3A/HPRT1/AKR1A1/TK2	8
GO:0008406	gonad development	17/1068	221/18722	0.129703840013421	0.274894705700087	NUPR1/ARRB2/FLNA/RETN/MGST1/VEGFA/TNFSF10/ERCC1/SGPL1/FNDC3A/CEBPB/ARID4A/TGFBR1/UBE3A/BAX/HSD17B4/RAB13	17
GO:0006164	purine nucleotide biosynthetic process	15/1068	191/18722	0.130845458505191	0.277205376558309	TMSB4X/TREM2/PPT1/PDK4/TGFB1/ATP6V1A/IMPDH1/PRKAG2/ACSL1/PAPSS1/HPRT1/STAT3/ACAT1/ADCY7/ACSL4	15
GO:0045017	glycerolipid biosynthetic process	19/1068	252/18722	0.131192042253572	0.277830557299951	FABP5/C3/LPL/PLSCR1/LPCAT2/AGPAT2/LPGAT1/NR1H3/INPP5D/ACSL1/SOCS3/MTMR6/EFR3A/ATM/CEPT1/PLA2G15/ACSL4/PIK3R1/SOCS6	19
GO:0099177	regulation of trans-synaptic signaling	31/1068	440/18722	0.131864982615126	0.279146114629744	APOE/FABP5/TYROBP/SRGN/GLUL/YWHAH/LGMN/MEF2C/ARRB2/GNAI2/RETN/RAP1A/PRNP/LILRB2/MCTP1/JAK2/SLC6A6/ABR/LRRK2/PTK2B/SLC30A1/IL1B/CYFIP1/STAT3/STX4/CALM3/SLC1A3/FLOT1/RAB8A/KIF5B/YWHAG	31
GO:0046425	regulation of receptor signaling pathway via JAK-STAT	9/1068	103/18722	0.133361132384461	0.28215372635649	PTPRC/CD300A/IL10RA/JAK2/IL6R/SH2B3/PTK2B/PARP14/SOCS3	9
GO:0043954	cellular component maintenance	6/1068	61/18722	0.133442607424344	0.28215372635649	APOE/TREM2/CSF1R/CHCHD10/PRNP/ARF6	6
GO:0090342	regulation of cell aging	6/1068	61/18722	0.133442607424344	0.28215372635649	B2M/YBX1/ABI3/VASH1/NAMPT/BCL6	6
GO:0010657	muscle cell apoptotic process	8/1068	89/18722	0.134878419049974	0.285077927612087	NUPR1/SOD2/HMOX1/ARRB2/JAK2/STK4/PTK2B/GNB1	8
GO:0006024	glycosaminoglycan biosynthetic process	7/1068	75/18722	0.135169771765342	0.285562181898544	DSE/HS3ST1/TGFB1/CSGALNACT2/IL1B/HEXA/B3GNT2	7
GO:0051302	regulation of cell division	14/1068	177/18722	0.135213375602443	0.285562181898544	TXNIP/EVI2B/RHOA/YBX1/CIB1/VEGFA/TGFB1/PLK3/IL1B/VEGFB/CALM3/NUP62/CDC42/CHMP3	14
GO:0001893	maternal placenta development	4/1068	35/18722	0.136643724354409	0.287205147806951	SPP1/CTSB/JUNB/PRDM1	4
GO:0003298	physiological muscle hypertrophy	4/1068	35/18722	0.136643724354409	0.287205147806951	HAMP/PAK1/AKAP13/RGS2	4
GO:0003301	physiological cardiac muscle hypertrophy	4/1068	35/18722	0.136643724354409	0.287205147806951	HAMP/PAK1/AKAP13/RGS2	4
GO:0006471	protein ADP-ribosylation	4/1068	35/18722	0.136643724354409	0.287205147806951	PARP9/PARP12/PARP4/PARP14	4
GO:0008608	attachment of spindle microtubules to kinetochore	4/1068	35/18722	0.136643724354409	0.287205147806951	RB1/APC/CDC42/RCC2	4
GO:0009119	ribonucleoside metabolic process	4/1068	35/18722	0.136643724354409	0.287205147806951	UPP1/APOBEC3C/APOBEC3A/HPRT1	4
GO:0035633	maintenance of blood-brain barrier	4/1068	35/18722	0.136643724354409	0.287205147806951	ACTB/PECAM1/MBP/VEGFA	4
GO:0045454	cell redox homeostasis	4/1068	35/18722	0.136643724354409	0.287205147806951	GPX1/SLC11A1/HVCN1/ERO1A	4
GO:0061049	cell growth involved in cardiac muscle cell development	4/1068	35/18722	0.136643724354409	0.287205147806951	HAMP/PAK1/AKAP13/RGS2	4
GO:0106056	regulation of calcineurin-mediated signaling	4/1068	35/18722	0.136643724354409	0.287205147806951	CLEC7A/HOMER3/CIB1/PRNP	4
GO:1903514	release of sequestered calcium ion into cytosol by endoplasmic reticulum	4/1068	35/18722	0.136643724354409	0.287205147806951	CCL3/SLC8A1/CALM3/GSTO1	4
GO:1905508	protein localization to microtubule organizing center	4/1068	35/18722	0.136643724354409	0.287205147806951	SNX10/APC/NUP62/CEP350	4
GO:0002686	negative regulation of leukocyte migration	5/1068	48/18722	0.136842927170436	0.287205147806951	DUSP1/HMOX1/CD300A/PTGER4/RIN3	5
GO:0015804	neutral amino acid transport	5/1068	48/18722	0.136842927170436	0.287205147806951	SLC38A6/SLC6A6/SFXN3/MFSD12/RGS2	5
GO:0032527	protein exit from endoplasmic reticulum	5/1068	48/18722	0.136842927170436	0.287205147806951	CD81/SORL1/HM13/TMEM30A/HERPUD1	5
GO:0048146	positive regulation of fibroblast proliferation	5/1068	48/18722	0.136842927170436	0.287205147806951	CD74/ZMIZ1/S100A6/CDKN1A/RNASEH2B	5
GO:0014896	muscle hypertrophy	9/1068	104/18722	0.139095756035084	0.291706451443961	CYBA/HAMP/MEF2A/TNFRSF1B/TNFRSF1A/ROCK1/PAK1/AKAP13/RGS2	9
GO:0060419	heart growth	9/1068	104/18722	0.139095756035084	0.291706451443961	HAMP/MEF2C/TGFBR2/RUNX1/PRKAR1A/TGFBR1/PAK1/AKAP13/RGS2	9
GO:0044272	sulfur compound biosynthetic process	12/1068	148/18722	0.139265106436166	0.291834762846427	PPT1/DSE/PDK4/CSGALNACT2/ACSL1/MGST2/PAPSS1/AKR1A1/ACAT1/MAT2A/ACSL4/B3GNT2	12
GO:0044839	cell cycle G2/M phase transition	12/1068	148/18722	0.139265106436166	0.291834762846427	TAOK3/ATF5/PLK3/CDKN1A/RNASEH2B/ATM/FBXL15/CALM3/FOXN3/BACH1/TAOK1/RCC2	12
GO:0006109	regulation of carbohydrate metabolic process	14/1068	178/18722	0.139543308635474	0.29219080069733	NUPR1/PLEK/FBP1/HIF1A/PDK4/P2RX7/TGFB1/DDIT4/PTAFR/SCARB2/PRKAG2/PTK2B/STAT3/RANBP2	14
GO:0035265	organ growth	14/1068	178/18722	0.139543308635474	0.29219080069733	PSAP/HAMP/MEF2C/TGFBR2/RUNX1/SASH3/STK4/SERP1/PRKAR1A/TGFBR1/PAK1/AKAP13/RGS2/UBE3A	14
GO:0071322	cellular response to carbohydrate stimulus	13/1068	163/18722	0.139648978251875	0.292298637178867	HLA-DRB1/LGALS1/CYBA/TREM2/CLEC7A/HIF1A/ZFP36L1/UCP2/RAC1/ABCG1/LRP1/STX4/KIF5B	13
GO:0002082	regulation of oxidative phosphorylation	3/1068	23/18722	0.140721389795791	0.293518600439926	NUPR1/RHOA/PPIF	3
GO:0021544	subpallium development	3/1068	23/18722	0.140721389795791	0.293518600439926	ZSWIM6/LRRK2/HPRT1	3
GO:0032740	positive regulation of interleukin-17 production	3/1068	23/18722	0.140721389795791	0.293518600439926	IL18/TGFB1/MYD88	3
GO:0035640	exploration behavior	3/1068	23/18722	0.140721389795791	0.293518600439926	APOE/LRRK2/UBE3A	3
GO:0042438	melanin biosynthetic process	3/1068	23/18722	0.140721389795791	0.293518600439926	ZEB2/MFSD12/APPL1	3
GO:0051457	maintenance of protein location in nucleus	3/1068	23/18722	0.140721389795791	0.293518600439926	CHCHD10/SP100/MORC3	3
GO:0060575	intestinal epithelial cell differentiation	3/1068	23/18722	0.140721389795791	0.293518600439926	HIF1A/PRDM1/CDKN1A	3
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	3/1068	23/18722	0.140721389795791	0.293518600439926	HAMP/PAK1/RGS2	3
GO:2001169	regulation of ATP biosynthetic process	3/1068	23/18722	0.140721389795791	0.293518600439926	TMSB4X/TREM2/STAT3	3
GO:0032835	glomerulus development	6/1068	62/18722	0.141083381465129	0.293578509201752	MEF2C/PECAM1/NOTCH2/IL6R/IQGAP1/EGR1	6
GO:0046173	polyol biosynthetic process	6/1068	62/18722	0.141083381465129	0.293578509201752	ASAH1/PLEK/CYP27A1/PTAFR/PTK2B/ACER3	6
GO:0046824	positive regulation of nucleocytoplasmic transport	6/1068	62/18722	0.141083381465129	0.293578509201752	FLNA/TGFB1/JAK2/IL1B/HCLS1/PIK3R1	6
GO:1902750	negative regulation of cell cycle G2/M phase transition	6/1068	62/18722	0.141083381465129	0.293578509201752	TAOK3/ATF5/CDKN1A/ATM/FOXN3/TAOK1	6
GO:0030901	midbrain development	8/1068	90/18722	0.141130958648878	0.293578509201752	YWHAH/ACTB/GNB4/RHOA/NR4A2/MBP/CALM3/CDC42	8
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	8/1068	90/18722	0.141130958648878	0.293578509201752	HSPA1A/PLK3/LRRK2/GABARAP/CEBPA/HERPUD1/PIAS1/SUMO2	8
GO:0034644	cellular response to UV	8/1068	90/18722	0.141130958648878	0.293578509201752	TIMP1/CARD16/CRIP1/MMP2/CDKN1A/ERCC1/BAX/PIK3R1	8
GO:0001937	negative regulation of endothelial cell proliferation	7/1068	76/18722	0.142044136820967	0.29490964304961	APOE/STAT1/MEF2C/ALOX5/VASH1/RGCC/TGFBR1	7
GO:0008652	cellular amino acid biosynthetic process	7/1068	76/18722	0.142044136820967	0.29490964304961	GLUL/SDS/ALDH1A1/DPYD/SDSL/GLS/SLC1A3	7
GO:0014823	response to activity	7/1068	76/18722	0.142044136820967	0.29490964304961	CYBA/CXCR4/SOD2/HIF1A/METRNL/SCO2/CAB39	7
GO:0014855	striated muscle cell proliferation	7/1068	76/18722	0.142044136820967	0.29490964304961	MEF2C/TGFBR2/RUNX1/JAK2/STAT3/PRKAR1A/TGFBR1	7
GO:0140115	export across plasma membrane	7/1068	76/18722	0.142044136820967	0.29490964304961	SLC8A1/KCNE3/ATP1B1/ABCA1/CALM3/ATP1B3/ATP1A1	7
GO:0001508	action potential	11/1068	134/18722	0.143355873492992	0.297518574372379	YWHAH/SLC8A1/CD36/FLNA/KCNAB2/KCNE3/ATP1B1/GNA15/CALM3/GNAQ/ATP1A1	11
GO:0006941	striated muscle contraction	14/1068	179/18722	0.143948894079135	0.298204426583056	CXCR4/SLC8A1/FLNA/KCNE3/RCSD1/ATP1B1/VEGFB/CALM3/GSTO1/GSN/NR4A1/GAA/RGS2/ATP1A1	14
GO:0007626	locomotory behavior	14/1068	179/18722	0.143948894079135	0.298204426583056	APOE/CSTB/PPT1/ID2/ARRB2/NR4A2/PBX3/APH1B/LRRK2/HPRT1/ABHD12/GAA/UBE3A/EGR1	14
GO:0050806	positive regulation of synaptic transmission	13/1068	164/18722	0.14426713711524	0.298204426583056	APOE/TYROBP/GLUL/LGMN/ARRB2/RETN/PRNP/LILRB2/PTK2B/STX4/SLC1A3/FLOT1/KIF5B	13
GO:2000058	regulation of ubiquitin-dependent protein catabolic process	13/1068	164/18722	0.14426713711524	0.298204426583056	LAPTM5/SDCBP/HSPA1A/PLK3/LRRK2/PTK2B/GABARAP/CEBPA/HERPUD1/UBE3A/PIAS1/CAMLG/SUMO2	13
GO:2001022	positive regulation of response to DNA damage stimulus	9/1068	105/18722	0.14495489475772	0.298204426583056	SKIL/ACTR2/PARP9/WAS/DTX3L/SPRED1/ATM/DDX5/ZNF385A	9
GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	5/1068	49/18722	0.145709016382946	0.298204426583056	PTPRC/TGFB1/BCL6/STAT6/ERCC1	5
GO:0002208	somatic diversification of immunoglobulins involved in immune response	5/1068	49/18722	0.145709016382946	0.298204426583056	PTPRC/TGFB1/BCL6/STAT6/ERCC1	5
GO:0006778	porphyrin-containing compound metabolic process	5/1068	49/18722	0.145709016382946	0.298204426583056	TSPO/HMOX1/SLCO2B1/BLVRB/BLVRA	5
GO:0030195	negative regulation of blood coagulation	5/1068	49/18722	0.145709016382946	0.298204426583056	APOE/CD9/PLAU/SH2B3/SERPING1	5
GO:0043330	response to exogenous dsRNA	5/1068	49/18722	0.145709016382946	0.298204426583056	IFIT1/IRAK3/IFIH1/NFKBIA/FLOT1	5
GO:0043457	regulation of cellular respiration	5/1068	49/18722	0.145709016382946	0.298204426583056	NUPR1/HIF1A/RHOA/IFNAR1/PPIF	5
GO:0045190	isotype switching	5/1068	49/18722	0.145709016382946	0.298204426583056	PTPRC/TGFB1/BCL6/STAT6/ERCC1	5
GO:0046580	negative regulation of Ras protein signal transduction	5/1068	49/18722	0.145709016382946	0.298204426583056	FBP1/TIMP2/BCL6/NUP62/ARHGAP24	5
GO:0070849	response to epidermal growth factor	5/1068	49/18722	0.145709016382946	0.298204426583056	ZFP36L2/ZFP36/ZFP36L1/DUSP3/IQGAP1	5
GO:0086009	membrane repolarization	5/1068	49/18722	0.145709016382946	0.298204426583056	FLNA/KCNE3/ATP1B1/ATP1B3/ATP1A1	5
GO:0001821	histamine secretion	2/1068	12/18722	0.147015530446469	0.298204426583056	LYN/BTK	2
GO:0002903	negative regulation of B cell apoptotic process	2/1068	12/18722	0.147015530446469	0.298204426583056	CD74/BCL6	2
GO:0006216	cytidine catabolic process	2/1068	12/18722	0.147015530446469	0.298204426583056	APOBEC3C/APOBEC3A	2
GO:0009972	cytidine deamination	2/1068	12/18722	0.147015530446469	0.298204426583056	APOBEC3C/APOBEC3A	2
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	2/1068	12/18722	0.147015530446469	0.298204426583056	PTPRJ/LRP1	2
GO:0016554	cytidine to uridine editing	2/1068	12/18722	0.147015530446469	0.298204426583056	APOBEC3C/APOBEC3A	2
GO:0030157	pancreatic juice secretion	2/1068	12/18722	0.147015530446469	0.298204426583056	NR1H3/WNK1	2
GO:0031953	negative regulation of protein autophosphorylation	2/1068	12/18722	0.147015530446469	0.298204426583056	PTPRC/ENG	2
GO:0032780	negative regulation of ATPase activity	2/1068	12/18722	0.147015530446469	0.298204426583056	OXA1L/PPIF	2
GO:0032823	regulation of natural killer cell differentiation	2/1068	12/18722	0.147015530446469	0.298204426583056	AXL/PRDM1	2
GO:0032908	regulation of transforming growth factor beta1 production	2/1068	12/18722	0.147015530446469	0.298204426583056	TYROBP/ATP6AP2	2
GO:0034333	adherens junction assembly	2/1068	12/18722	0.147015530446469	0.298204426583056	ACTB/PAK2	2
GO:0034370	triglyceride-rich lipoprotein particle remodeling	2/1068	12/18722	0.147015530446469	0.298204426583056	APOE/LPL	2
GO:0034372	very-low-density lipoprotein particle remodeling	2/1068	12/18722	0.147015530446469	0.298204426583056	APOE/LPL	2
GO:0038180	nerve growth factor signaling pathway	2/1068	12/18722	0.147015530446469	0.298204426583056	CORO1A/RAP1A	2
GO:0038203	TORC2 signaling	2/1068	12/18722	0.147015530446469	0.298204426583056	NCKAP1L/SESN3	2
GO:0043476	pigment accumulation	2/1068	12/18722	0.147015530446469	0.298204426583056	CD63/RAB32	2
GO:0043482	cellular pigment accumulation	2/1068	12/18722	0.147015530446469	0.298204426583056	CD63/RAB32	2
GO:0046087	cytidine metabolic process	2/1068	12/18722	0.147015530446469	0.298204426583056	APOBEC3C/APOBEC3A	2
GO:0051639	actin filament network formation	2/1068	12/18722	0.147015530446469	0.298204426583056	LCP1/ARPC5	2
GO:0060019	radial glial cell differentiation	2/1068	12/18722	0.147015530446469	0.298204426583056	RHOA/STAT3	2
GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	2/1068	12/18722	0.147015530446469	0.298204426583056	PAK1/RGS2	2
GO:0061517	macrophage proliferation	2/1068	12/18722	0.147015530446469	0.298204426583056	TREM2/CSF1R	2
GO:0070943	neutrophil-mediated killing of symbiont cell	2/1068	12/18722	0.147015530446469	0.298204426583056	TREM1/MYD88	2
GO:0071472	cellular response to salt stress	2/1068	12/18722	0.147015530446469	0.298204426583056	ZFP36L1/MICU1	2
GO:0071635	negative regulation of transforming growth factor beta production	2/1068	12/18722	0.147015530446469	0.298204426583056	TYROBP/LILRB1	2
GO:0072015	glomerular visceral epithelial cell development	2/1068	12/18722	0.147015530446469	0.298204426583056	NOTCH2/IQGAP1	2
GO:0072537	fibroblast activation	2/1068	12/18722	0.147015530446469	0.298204426583056	RPS6KA1/RGCC	2
GO:0090331	negative regulation of platelet aggregation	2/1068	12/18722	0.147015530446469	0.298204426583056	CD9/SH2B3	2
GO:0090385	phagosome-lysosome fusion	2/1068	12/18722	0.147015530446469	0.298204426583056	ARL8B/RAB7A	2
GO:0097152	mesenchymal cell apoptotic process	2/1068	12/18722	0.147015530446469	0.298204426583056	HIF1A/ETV6	2
GO:0098974	postsynaptic actin cytoskeleton organization	2/1068	12/18722	0.147015530446469	0.298204426583056	ACTB/DBNL	2
GO:0150065	regulation of deacetylase activity	2/1068	12/18722	0.147015530446469	0.298204426583056	VEGFA/LRRK2	2
GO:1901503	ether biosynthetic process	2/1068	12/18722	0.147015530446469	0.298204426583056	LPCAT2/ALOX5	2
GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	2/1068	12/18722	0.147015530446469	0.298204426583056	PLXNC1/PLXND1	2
GO:1902950	regulation of dendritic spine maintenance	2/1068	12/18722	0.147015530446469	0.298204426583056	APOE/PRNP	2
GO:1903441	protein localization to ciliary membrane	2/1068	12/18722	0.147015530446469	0.298204426583056	GGA1/RAB29	2
GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA	2/1068	12/18722	0.147015530446469	0.298204426583056	TGFB1/DDX5	2
GO:1903909	regulation of receptor clustering	2/1068	12/18722	0.147015530446469	0.298204426583056	CD81/GSN	2
GO:2000009	negative regulation of protein localization to cell surface	2/1068	12/18722	0.147015530446469	0.298204426583056	PICALM/ARF6	2
GO:2000508	regulation of dendritic cell chemotaxis	2/1068	12/18722	0.147015530446469	0.298204426583056	SPI1/LGALS9	2
GO:0014741	negative regulation of muscle hypertrophy	4/1068	36/18722	0.147223238031368	0.298204426583056	TNFRSF1B/TNFRSF1A/PAK1/RGS2	4
GO:0038179	neurotrophin signaling pathway	4/1068	36/18722	0.147223238031368	0.298204426583056	CORO1A/RAP1A/DDIT4/CYFIP1	4
GO:0045191	regulation of isotype switching	4/1068	36/18722	0.147223238031368	0.298204426583056	PTPRC/TGFB1/BCL6/STAT6	4
GO:0060251	regulation of glial cell proliferation	4/1068	36/18722	0.147223238031368	0.298204426583056	TSPO/LYN/IL1B/SKI	4
GO:0070306	lens fiber cell differentiation	4/1068	36/18722	0.147223238031368	0.298204426583056	VIM/SKIL/MAF/SPRED1	4
GO:0070670	response to interleukin-4	4/1068	36/18722	0.147223238031368	0.298204426583056	CORO1A/CD300LF/STAT6/PARP14	4
GO:0097009	energy homeostasis	4/1068	36/18722	0.147223238031368	0.298204426583056	CD36/METRNL/PRCP/STAT3	4
GO:1901658	glycosyl compound catabolic process	4/1068	36/18722	0.147223238031368	0.298204426583056	UPP1/DPYD/APOBEC3C/APOBEC3A	4
GO:0055006	cardiac cell development	8/1068	91/18722	0.14752510521682	0.298703740243888	HAMP/MEF2A/SLC8A1/VEGFA/PAK1/AKAP13/RGS2/PLEC	8
GO:0046661	male sex differentiation	13/1068	165/18722	0.148966624097736	0.301283322200669	NUPR1/LHFPL2/FLNA/MGST1/TNFSF10/ERCC1/SGPL1/FNDC3A/ARID4A/TGFBR1/BAX/HSD17B4/RAB13	13
GO:0071772	response to BMP	13/1068	165/18722	0.148966624097736	0.301283322200669	SORL1/SKIL/TGFB1/ENG/NOTCH2/FBXL15/HTRA1/DDX5/UBE2D1/SKI/XIAP/UBE2D3/EGR1	13
GO:0071773	cellular response to BMP stimulus	13/1068	165/18722	0.148966624097736	0.301283322200669	SORL1/SKIL/TGFB1/ENG/NOTCH2/FBXL15/HTRA1/DDX5/UBE2D1/SKI/XIAP/UBE2D3/EGR1	13
GO:0002200	somatic diversification of immune receptors	7/1068	77/18722	0.149083037483109	0.301292910209309	SAMHD1/PTPRC/TGFB1/BCL6/STAT6/ERCC1/ADAR	7
GO:0007492	endoderm development	7/1068	77/18722	0.149083037483109	0.301292910209309	ITGB2/DUSP1/ZFP36L1/ITGA4/MMP2/ITGA5/DUSP2	7
GO:0090287	regulation of cellular response to growth factor stimulus	22/1068	304/18722	0.150049186902556	0.303131940294343	ZEB2/SORL1/CD63/SKIL/HIF1A/SDCBP/HSPA1A/TGFB1/ENG/NOTCH2/C20orf27/SPRED1/ITGA5/IL1B/CYFIP1/FBXL15/HTRA1/ADAM17/UBE2D1/SKI/XIAP/UBE2D3	22
GO:2000278	regulation of DNA biosynthetic process	9/1068	106/18722	0.150936485443135	0.304810357579026	DUSP1/ARRB2/HGF/KLF4/PARP4/PTK2B/CDKN1A/RGCC/ATM	9
GO:0001763	morphogenesis of a branching structure	15/1068	196/18722	0.151902046158104	0.306645507321036	CTSZ/CTSH/GRB2/HGF/VEGFA/ST14/PLXND1/ENG/TGFBR2/PRDM1/LRRK2/STK4/SOCS3/RTN4/PAK1	15
GO:0002455	humoral immune response mediated by circulating immunoglobulin	10/1068	121/18722	0.15291690879564	0.308578773321344	C1QB/TREM2/C3/C1QA/CD81/C1QC/PTPRC/C2/PTPN6/SERPING1	10
GO:0001779	natural killer cell differentiation	3/1068	24/18722	0.15440189597102	0.309607071965673	PTPRC/AXL/PRDM1	3
GO:0002438	acute inflammatory response to antigenic stimulus	3/1068	24/18722	0.15440189597102	0.309607071965673	C3/HLA-E/BTK	3
GO:0006582	melanin metabolic process	3/1068	24/18722	0.15440189597102	0.309607071965673	ZEB2/MFSD12/APPL1	3
GO:0010155	regulation of proton transport	3/1068	24/18722	0.15440189597102	0.309607071965673	TMSB4X/TCIRG1/PPIF	3
GO:0010226	response to lithium ion	3/1068	24/18722	0.15440189597102	0.309607071965673	PTK2B/ADCY7/CEBPA	3
GO:0030810	positive regulation of nucleotide biosynthetic process	3/1068	24/18722	0.15440189597102	0.309607071965673	TMSB4X/TREM2/STAT3	3
GO:0032528	microvillus organization	3/1068	24/18722	0.15440189597102	0.309607071965673	FXYD5/TWF2/RAP2A	3
GO:0033032	regulation of myeloid cell apoptotic process	3/1068	24/18722	0.15440189597102	0.309607071965673	MEF2C/IRF7/ADAM17	3
GO:0048641	regulation of skeletal muscle tissue development	3/1068	24/18722	0.15440189597102	0.309607071965673	MEF2C/TGFB1/FLOT1	3
GO:0050687	negative regulation of defense response to virus	3/1068	24/18722	0.15440189597102	0.309607071965673	FGL2/HTRA1/PCBP2	3
GO:0061162	establishment of monopolar cell polarity	3/1068	24/18722	0.15440189597102	0.309607071965673	MSN/RHOA/CDC42	3
GO:0071294	cellular response to zinc ion	3/1068	24/18722	0.15440189597102	0.309607071965673	TSPO/HVCN1/MT1X	3
GO:0072010	glomerular epithelium development	3/1068	24/18722	0.15440189597102	0.309607071965673	PECAM1/NOTCH2/IQGAP1	3
GO:1900373	positive regulation of purine nucleotide biosynthetic process	3/1068	24/18722	0.15440189597102	0.309607071965673	TMSB4X/TREM2/STAT3	3
GO:2000209	regulation of anoikis	3/1068	24/18722	0.15440189597102	0.309607071965673	PDK4/ITGA5/MCL1	3
GO:2000679	positive regulation of transcription regulatory region DNA binding	3/1068	24/18722	0.15440189597102	0.309607071965673	RB1/KLF4/TGFB1	3
GO:2001026	regulation of endothelial cell chemotaxis	3/1068	24/18722	0.15440189597102	0.309607071965673	TMSB4X/LGMN/VEGFA	3
GO:0050873	brown fat cell differentiation	5/1068	50/18722	0.154813617465416	0.310086963564732	METRNL/CEBPB/ERO1A/CEBPA/RGS2	5
GO:1900047	negative regulation of hemostasis	5/1068	50/18722	0.154813617465416	0.310086963564732	APOE/CD9/PLAU/SH2B3/SERPING1	5
GO:1902930	regulation of alcohol biosynthetic process	5/1068	50/18722	0.154813617465416	0.310086963564732	APOE/PLEK/PTAFR/PTK2B/ABCG1	5
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	7/1068	78/18722	0.156282374428572	0.31268064234949	LAPTM5/CTSH/PYCARD/BID/JAK2/RPS27L/BAX	7
GO:0008306	associative learning	7/1068	78/18722	0.156282374428572	0.31268064234949	LGMN/FOS/PPT1/HIF1A/ACTR2/BTG2/PIAS1	7
GO:0043297	apical junction assembly	7/1068	78/18722	0.156282374428572	0.31268064234949	MTDH/PECAM1/RHOA/PAK2/ROCK1/APC/RAB13	7
GO:0001990	regulation of systemic arterial blood pressure by hormone	4/1068	37/18722	0.158107352926254	0.315746586376783	CYBA/CTSZ/RHOA/ATP6AP2	4
GO:0003016	respiratory system process	4/1068	37/18722	0.158107352926254	0.315746586376783	GLS/PBX3/GAA/ZFAND5	4
GO:0031646	positive regulation of nervous system process	4/1068	37/18722	0.158107352926254	0.315746586376783	HGF/ITGAX/TNFRSF1B/PTAFR	4
GO:0034260	negative regulation of GTPase activity	4/1068	37/18722	0.158107352926254	0.315746586376783	ARRB2/LRRK2/RCC2/WNK1	4
GO:0043403	skeletal muscle tissue regeneration	4/1068	37/18722	0.158107352926254	0.315746586376783	GPX1/CD9/CD81/TGFBR2	4
GO:0001655	urogenital system development	24/1068	338/18722	0.158608447138039	0.316630107568205	PSAP/CTSH/STAT1/MEF2C/PECAM1/RHOA/VEGFA/PLXND1/CRIP1/PRDM1/NOTCH2/IL6R/LRRK2/PRKX/SGPL1/CNTRL/ACAT1/AP1B1/IQGAP1/TGFBR1/TMED10/UBE3A/BAX/EGR1	24
GO:0016125	sterol metabolic process	12/1068	152/18722	0.159205575892368	0.317704618163912	APOE/NPC2/LIPA/SOAT1/CYP27A1/OSBPL1A/ACAA2/APOBR/PRKAG2/ABCG1/ABCA1/CEBPA	12
GO:0000086	G2/M transition of mitotic cell cycle	11/1068	137/18722	0.159280340618112	0.317736309787554	TAOK3/PLK3/CDKN1A/RNASEH2B/ATM/FBXL15/CALM3/FOXN3/BACH1/TAOK1/RCC2	11
GO:1901796	regulation of signal transduction by p53 class mediator	8/1068	93/18722	0.160726561647934	0.320502781467943	CD74/SGK1/CD44/PLK3/SPRED1/ATM/DDX5/ZNF385A	8
GO:0034440	lipid oxidation	9/1068	108/18722	0.163258049914189	0.325137777034552	PLA2G7/PDK4/ALOX5/ACAA2/PRKAG2/ACAT1/CPT1A/SCP2/HSD17B4	9
GO:0098659	inorganic cation import across plasma membrane	9/1068	108/18722	0.163258049914189	0.325137777034552	SLC8A1/PRNP/TRPM2/ATP1B1/SLC31A1/SLC30A1/WNK1/ATP1B3/ATP1A1	9
GO:0099587	inorganic ion import across plasma membrane	9/1068	108/18722	0.163258049914189	0.325137777034552	SLC8A1/PRNP/TRPM2/ATP1B1/SLC31A1/SLC30A1/WNK1/ATP1B3/ATP1A1	9
GO:0006814	sodium ion transport	18/1068	245/18722	0.163291952513646	0.325137777034552	SGK1/FXYD5/YWHAH/SLC8A1/SLC4A7/P2RX7/SLC38A6/KCNE3/TRPM2/SLC6A6/ATP1B1/GLRX/COMMD9/KLHL24/WNK1/KIF5B/ATP1B3/ATP1A1	18
GO:0006023	aminoglycan biosynthetic process	7/1068	79/18722	0.163637811564992	0.325586147199372	DSE/HS3ST1/TGFB1/CSGALNACT2/IL1B/HEXA/B3GNT2	7
GO:0060420	regulation of heart growth	7/1068	79/18722	0.163637811564992	0.325586147199372	HAMP/MEF2C/TGFBR2/RUNX1/TGFBR1/PAK1/RGS2	7
GO:0010656	negative regulation of muscle cell apoptotic process	5/1068	51/18722	0.164146524705111	0.326117322278638	NUPR1/HMOX1/ARRB2/JAK2/PTK2B	5
GO:0032873	negative regulation of stress-activated MAPK cascade	5/1068	51/18722	0.164146524705111	0.326117322278638	TREM2/DUSP1/TAOK3/SIRPA/DUSP3	5
GO:0045661	regulation of myoblast differentiation	5/1068	51/18722	0.164146524705111	0.326117322278638	IL18/MEF2C/ZFP36L1/TGFB1/BTG1	5
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	5/1068	51/18722	0.164146524705111	0.326117322278638	TREM2/DUSP1/TAOK3/SIRPA/DUSP3	5
GO:0120254	olefinic compound metabolic process	12/1068	153/18722	0.164407384930724	0.326515365876402	GPX1/ALDH1A1/ALOX5/TBXAS1/PTGS1/RDH11/GPX4/ABHD12/DHRS3/DHRS4/SCP2/EGR1	12
GO:0060389	pathway-restricted SMAD protein phosphorylation	6/1068	65/18722	0.16516435242144	0.326660680856544	SDCBP/TGFB1/ENG/TGFBR2/LRP1/TGFBR1	6
GO:0006417	regulation of translation	32/1068	468/18722	0.165483402912799	0.326660680856544	VIM/ZFP36L2/ZFP36/ZFP36L1/RHOA/YBX1/PABPC1/EIF4EBP1/PTAFR/RPS6KA1/PTK2B/BTG2/CYFIP1/SERP1/MIF4GD/STAT3/QKI/RPS27L/EIF2AK2/DAPK1/RPS6KA3/EIF4G3/ROCK1/PPP1R15A/EIF2S3/ZNF385A/DNAJC3/EIF1/PKM/UHMK1/RGS2/CNBP	32
GO:0001822	kidney development	21/1068	293/18722	0.167138028923856	0.326660680856544	CTSH/STAT1/MEF2C/PECAM1/RHOA/VEGFA/PLXND1/PRDM1/NOTCH2/IL6R/LRRK2/PRKX/SGPL1/CNTRL/ACAT1/AP1B1/IQGAP1/TGFBR1/TMED10/BAX/EGR1	21
GO:0001768	establishment of T cell polarity	2/1068	13/18722	0.167483210225097	0.326660680856544	DOCK2/GSN	2
GO:0001973	G protein-coupled adenosine receptor signaling pathway	2/1068	13/18722	0.167483210225097	0.326660680856544	GNAI2/ADORA3	2
GO:0002087	regulation of respiratory gaseous exchange by nervous system process	2/1068	13/18722	0.167483210225097	0.326660680856544	GLS/PBX3	2
GO:0002638	negative regulation of immunoglobulin production	2/1068	13/18722	0.167483210225097	0.326660680856544	TMBIM6/BCL6	2
GO:0003222	ventricular trabecula myocardium morphogenesis	2/1068	13/18722	0.167483210225097	0.326660680856544	ENG/TGFBR1	2
GO:0006586	indolalkylamine metabolic process	2/1068	13/18722	0.167483210225097	0.326660680856544	IL4I1/KYNU	2
GO:0006983	ER overload response	2/1068	13/18722	0.167483210225097	0.326660680856544	BID/TMCO1	2
GO:0009650	UV protection	2/1068	13/18722	0.167483210225097	0.326660680856544	GPX1/ERCC1	2
GO:0010755	regulation of plasminogen activation	2/1068	13/18722	0.167483210225097	0.326660680856544	CTSZ/RUNX1	2
GO:0010917	negative regulation of mitochondrial membrane potential	2/1068	13/18722	0.167483210225097	0.326660680856544	BNIP3L/BAX	2
GO:0014842	regulation of skeletal muscle satellite cell proliferation	2/1068	13/18722	0.167483210225097	0.326660680856544	JAK2/STAT3	2
GO:0016322	neuron remodeling	2/1068	13/18722	0.167483210225097	0.326660680856544	C3/C1QA	2
GO:0031272	regulation of pseudopodium assembly	2/1068	13/18722	0.167483210225097	0.326660680856544	APC/CDC42	2
GO:0031274	positive regulation of pseudopodium assembly	2/1068	13/18722	0.167483210225097	0.326660680856544	APC/CDC42	2
GO:0032252	secretory granule localization	2/1068	13/18722	0.167483210225097	0.326660680856544	TANC2/KIF5B	2
GO:0032352	positive regulation of hormone metabolic process	2/1068	13/18722	0.167483210225097	0.326660680856544	HIF1A/EGR1	2
GO:0032429	regulation of phospholipase A2 activity	2/1068	13/18722	0.167483210225097	0.326660680856544	PPT1/LRP1	2
GO:0032905	transforming growth factor beta1 production	2/1068	13/18722	0.167483210225097	0.326660680856544	TYROBP/ATP6AP2	2
GO:0035588	G protein-coupled purinergic receptor signaling pathway	2/1068	13/18722	0.167483210225097	0.326660680856544	GNAI2/ADORA3	2
GO:0036462	TRAIL-activated apoptotic signaling pathway	2/1068	13/18722	0.167483210225097	0.326660680856544	SPI1/ATF3	2
GO:0042308	negative regulation of protein import into nucleus	2/1068	13/18722	0.167483210225097	0.326660680856544	CD36/MDFIC	2
GO:0042362	fat-soluble vitamin biosynthetic process	2/1068	13/18722	0.167483210225097	0.326660680856544	PLTP/CYP27A1	2
GO:0042541	hemoglobin biosynthetic process	2/1068	13/18722	0.167483210225097	0.326660680856544	HIF1A/KLF4	2
GO:0043201	response to leucine	2/1068	13/18722	0.167483210225097	0.326660680856544	RRAGD/SESN3	2
GO:0046512	sphingosine biosynthetic process	2/1068	13/18722	0.167483210225097	0.326660680856544	ASAH1/ACER3	2
GO:0046520	sphingoid biosynthetic process	2/1068	13/18722	0.167483210225097	0.326660680856544	ASAH1/ACER3	2
GO:0046642	negative regulation of alpha-beta T cell proliferation	2/1068	13/18722	0.167483210225097	0.326660680856544	LGALS9/TNFRSF14	2
GO:0046689	response to mercury ion	2/1068	13/18722	0.167483210225097	0.326660680856544	AQP9/UBE2D3	2
GO:0048070	regulation of developmental pigmentation	2/1068	13/18722	0.167483210225097	0.326660680856544	ZEB2/BAX	2
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	2/1068	13/18722	0.167483210225097	0.326660680856544	CALM3/GSTO1	2
GO:0051451	myoblast migration	2/1068	13/18722	0.167483210225097	0.326660680856544	PLEKHO1/ROCK1	2
GO:0051481	negative regulation of cytosolic calcium ion concentration	2/1068	13/18722	0.167483210225097	0.326660680856544	SLC8A1/LRP1	2
GO:0060707	trophoblast giant cell differentiation	2/1068	13/18722	0.167483210225097	0.326660680856544	PRDM1/SOCS3	2
GO:0061469	regulation of type B pancreatic cell proliferation	2/1068	13/18722	0.167483210225097	0.326660680856544	NUPR1/NR4A1	2
GO:0070234	positive regulation of T cell apoptotic process	2/1068	13/18722	0.167483210225097	0.326660680856544	LGALS9/ADAM8	2
GO:0072310	glomerular epithelial cell development	2/1068	13/18722	0.167483210225097	0.326660680856544	NOTCH2/IQGAP1	2
GO:0072672	neutrophil extravasation	2/1068	13/18722	0.167483210225097	0.326660680856544	PECAM1/ADAM8	2
GO:0090161	Golgi ribbon formation	2/1068	13/18722	0.167483210225097	0.326660680856544	STX6/TMED5	2
GO:0120305	regulation of pigmentation	2/1068	13/18722	0.167483210225097	0.326660680856544	ZEB2/BAX	2
GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response	2/1068	13/18722	0.167483210225097	0.326660680856544	BAX/PIK3R1	2
GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	2/1068	13/18722	0.167483210225097	0.326660680856544	PLXNC1/PLXND1	2
GO:1903651	positive regulation of cytoplasmic transport	2/1068	13/18722	0.167483210225097	0.326660680856544	SORL1/MSN	2
GO:1904590	negative regulation of protein import	2/1068	13/18722	0.167483210225097	0.326660680856544	CD36/MDFIC	2
GO:1905203	regulation of connective tissue replacement	2/1068	13/18722	0.167483210225097	0.326660680856544	RUNX1/ROCK1	2
GO:1905939	regulation of gonad development	2/1068	13/18722	0.167483210225097	0.326660680856544	NUPR1/RETN	2
GO:2000318	positive regulation of T-helper 17 type immune response	2/1068	13/18722	0.167483210225097	0.326660680856544	CLEC7A/NFKBIZ	2
GO:0014020	primary neural tube formation	8/1068	94/18722	0.167527593547711	0.326660680856544	HIF1A/ST14/TGFB1/VASP/RALA/PRKACB/SKI/PFN1	8
GO:0010447	response to acidic pH	3/1068	25/18722	0.16847603314006	0.326660680856544	CTSS/GPR65/LGMN	3
GO:0030318	melanocyte differentiation	3/1068	25/18722	0.16847603314006	0.326660680856544	ZEB2/MEF2C/MITF	3
GO:0033233	regulation of protein sumoylation	3/1068	25/18722	0.16847603314006	0.326660680856544	ZMIZ1/PIAS1/EGR1	3
GO:0044550	secondary metabolite biosynthetic process	3/1068	25/18722	0.16847603314006	0.326660680856544	ZEB2/MFSD12/APPL1	3
GO:0045109	intermediate filament organization	3/1068	25/18722	0.16847603314006	0.326660680856544	VIM/KLHL24/PLEC	3
GO:0045324	late endosome to vacuole transport	3/1068	25/18722	0.16847603314006	0.326660680856544	TMEM50A/CHMP3/CHMP1B	3
GO:0046949	fatty-acyl-CoA biosynthetic process	3/1068	25/18722	0.16847603314006	0.326660680856544	PPT1/ACSL1/ACSL4	3
GO:0050995	negative regulation of lipid catabolic process	3/1068	25/18722	0.16847603314006	0.326660680856544	APOC1/SORL1/IL1B	3
GO:0051450	myoblast proliferation	3/1068	25/18722	0.16847603314006	0.326660680856544	GPX1/HGF/MALAT1	3
GO:0061339	establishment or maintenance of monopolar cell polarity	3/1068	25/18722	0.16847603314006	0.326660680856544	MSN/RHOA/CDC42	3
GO:0098703	calcium ion import across plasma membrane	3/1068	25/18722	0.16847603314006	0.326660680856544	SLC8A1/PRNP/TRPM2	3
GO:0140448	signaling receptor ligand precursor processing	3/1068	25/18722	0.16847603314006	0.326660680856544	CTSZ/ATP6AP2/CASP1	3
GO:1903959	regulation of anion transmembrane transport	3/1068	25/18722	0.16847603314006	0.326660680856544	PRNP/PTAFR/RGS2	3
GO:1904385	cellular response to angiotensin	3/1068	25/18722	0.16847603314006	0.326660680856544	CYBA/AGTRAP/ROCK1	3
GO:1904753	negative regulation of vascular associated smooth muscle cell migration	3/1068	25/18722	0.16847603314006	0.326660680856544	MEF2C/RHOA/GNA13	3
GO:1905564	positive regulation of vascular endothelial cell proliferation	3/1068	25/18722	0.16847603314006	0.326660680856544	ITGA4/STAT3/ADAM17	3
GO:0001825	blastocyst formation	4/1068	38/18722	0.16927735808425	0.327039249632156	SKIL/JUNB/PTPN18/RTN4	4
GO:0007094	mitotic spindle assembly checkpoint signaling	4/1068	38/18722	0.16927735808425	0.327039249632156	DUSP1/ATM/APC/DYNC1LI1	4
GO:0035337	fatty-acyl-CoA metabolic process	4/1068	38/18722	0.16927735808425	0.327039249632156	PPT1/ACSL1/ACSL4/HSD17B4	4
GO:0071173	spindle assembly checkpoint signaling	4/1068	38/18722	0.16927735808425	0.327039249632156	DUSP1/ATM/APC/DYNC1LI1	4
GO:0071174	mitotic spindle checkpoint signaling	4/1068	38/18722	0.16927735808425	0.327039249632156	DUSP1/ATM/APC/DYNC1LI1	4
GO:0071398	cellular response to fatty acid	4/1068	38/18722	0.16927735808425	0.327039249632156	LPL/PDK4/PTAFR/CPT1A	4
GO:0072524	pyridine-containing compound metabolic process	4/1068	38/18722	0.16927735808425	0.327039249632156	PARP9/KYNU/NAMPT/PDXK	4
GO:0072538	T-helper 17 type immune response	4/1068	38/18722	0.16927735808425	0.327039249632156	CLEC7A/IL6R/STAT3/NFKBIZ	4
GO:0099622	cardiac muscle cell membrane repolarization	4/1068	38/18722	0.16927735808425	0.327039249632156	FLNA/KCNE3/ATP1B1/ATP1A1	4
GO:1901031	regulation of response to reactive oxygen species	4/1068	38/18722	0.16927735808425	0.327039249632156	CD36/HGF/LRRK2/SESN3	4
GO:0072522	purine-containing compound biosynthetic process	15/1068	200/18722	0.169980304489022	0.328240232288485	TMSB4X/TREM2/PPT1/PDK4/TGFB1/ATP6V1A/IMPDH1/PRKAG2/ACSL1/PAPSS1/HPRT1/STAT3/ACAT1/ADCY7/ACSL4	15
GO:0006401	RNA catabolic process	20/1068	278/18722	0.170020654048613	0.328240232288485	VIM/RNASET2/ZFP36L2/ZFP36/SLC11A1/ZFP36L1/RNASE6/YBX1/HSPA1A/OAS2/TNFRSF1B/PABPC1/MYD88/BTG2/RNASEH2B/ATM/PABPC4/DDX5/ROCK1/RNH1	20
GO:0010948	negative regulation of cell cycle process	21/1068	294/18722	0.17094067333062	0.329898381005733	GPNMB/ZFP36L2/DUSP1/ZFP36L1/RB1/TAOK3/ATF5/KLF4/PLK3/SLFN11/BCL6/CDKN1A/RNASEH2B/RPS27L/RGCC/ATM/PRKAR1A/FOXN3/APC/DYNC1LI1/TAOK1	21
GO:0042446	hormone biosynthetic process	6/1068	66/18722	0.173556151600467	0.334619711144784	TSPO/HIF1A/HSD17B11/SRD5A3/EGR1/ATP1A1	6
GO:2000573	positive regulation of DNA biosynthetic process	6/1068	66/18722	0.173556151600467	0.334619711144784	ARRB2/HGF/KLF4/PTK2B/RGCC/ATM	6
GO:0034204	lipid translocation	5/1068	52/18722	0.173697148057179	0.334619711144784	PLSCR1/P2RX7/ABCG1/ABCA1/TMEM30A	5
GO:0035196	production of miRNAs involved in gene silencing by miRNA	5/1068	52/18722	0.173697148057179	0.334619711144784	TGFB1/NCOR2/STAT3/ADAR/DDX5	5
GO:0072523	purine-containing compound catabolic process	5/1068	52/18722	0.173697148057179	0.334619711144784	SAMHD1/NUDT3/DPYD/HPRT1/ACAT1	5
GO:0008585	female gonad development	8/1068	95/18722	0.174457693626345	0.335845064148327	NUPR1/ARRB2/RETN/VEGFA/SGPL1/CEBPB/UBE3A/BAX	8
GO:0008593	regulation of Notch signaling pathway	8/1068	95/18722	0.174457693626345	0.335845064148327	BMP2K/ZMIZ1/BCL6/LFNG/STAT3/NFKBIA/TSPAN14/ADAM10	8
GO:0051054	positive regulation of DNA metabolic process	15/1068	201/18722	0.174665163858898	0.336124545000932	PTPRC/ARRB2/HGF/ACTR2/KLF4/PARP9/WAS/TGFB1/DTX3L/PTK2B/STAT6/ERCC1/RGCC/ATM/BAX	15
GO:0051147	regulation of muscle cell differentiation	12/1068	155/18722	0.175062307675771	0.336768703108186	HAMP/SOD2/ID2/MEF2C/ARRB2/YBX1/TGFB1/ENG/PAK1/RGS2/PIAS1/BHLHE41	12
GO:0050804	modulation of chemical synaptic transmission	30/1068	439/18722	0.175376842837332	0.337253543816909	APOE/TYROBP/SRGN/GLUL/YWHAH/LGMN/MEF2C/ARRB2/GNAI2/RETN/RAP1A/PRNP/LILRB2/MCTP1/JAK2/SLC6A6/ABR/LRRK2/PTK2B/SLC30A1/IL1B/CYFIP1/STAT3/STX4/CALM3/SLC1A3/FLOT1/RAB8A/KIF5B/YWHAG	30
GO:0007088	regulation of mitotic nuclear division	9/1068	110/18722	0.176041136764839	0.338169446060189	DUSP1/RB1/IL1B/RGCC/ATM/APC/NUP62/DYNC1LI1/CDC42	9
GO:0009408	response to heat	9/1068	110/18722	0.176041136764839	0.338169446060189	CD14/HMOX1/TFEC/LYN/HSPA1A/IRAK1/TRPM2/CDKN1A/ATM	9
GO:0018958	phenol-containing compound metabolic process	9/1068	110/18722	0.176041136764839	0.338169446060189	CTSB/ITGB2/ZEB2/NR4A2/ITGAM/MFSD12/HPRT1/FAH/APPL1	9
GO:0070585	protein localization to mitochondrion	10/1068	125/18722	0.176454138197739	0.338842181393238	TSPO/ISG15/BID/LRRK2/BNIP3L/RALA/CALM3/OXA1L/BAX/UBE2D3	10
GO:0048193	Golgi vesicle transport	21/1068	296/18722	0.178682772049228	0.34261255296445	LAPTM5/SORL1/VAMP5/TAPBP/GGA2/VPS13C/MYO5A/CSK/LRRK2/STX6/ATP2C1/GGA1/RAB8B/TMED5/TMED10/BCAP29/LAMP1/RAB10/ARF3/RAB8A/RAB13	21
GO:0000422	autophagy of mitochondrion	7/1068	81/18722	0.178798545060766	0.34261255296445	TSPO/HIF1A/VPS13C/BNIP3L/GABARAP/CISD2/ATG3	7
GO:0044773	mitotic DNA damage checkpoint signaling	7/1068	81/18722	0.178798545060766	0.34261255296445	TAOK3/PLK3/CDKN1A/RPS27L/ATM/FOXN3/TAOK1	7
GO:0051149	positive regulation of muscle cell differentiation	7/1068	81/18722	0.178798545060766	0.34261255296445	HAMP/SOD2/MEF2C/ARRB2/TGFB1/ENG/PIAS1	7
GO:0060968	regulation of gene silencing	7/1068	81/18722	0.178798545060766	0.34261255296445	ZFP36/NEAT1/TGFB1/NCOR2/STAT3/ADAR/DDX5	7
GO:0061726	mitochondrion disassembly	7/1068	81/18722	0.178798545060766	0.34261255296445	TSPO/HIF1A/VPS13C/BNIP3L/GABARAP/CISD2/ATG3	7
GO:0031577	spindle checkpoint signaling	4/1068	39/18722	0.180714169800291	0.345302287621235	DUSP1/ATM/APC/DYNC1LI1	4
GO:0042417	dopamine metabolic process	4/1068	39/18722	0.180714169800291	0.345302287621235	ITGB2/NR4A2/ITGAM/HPRT1	4
GO:0046461	neutral lipid catabolic process	4/1068	39/18722	0.180714169800291	0.345302287621235	SORL1/LPL/ABHD2/ABHD12	4
GO:0046464	acylglycerol catabolic process	4/1068	39/18722	0.180714169800291	0.345302287621235	SORL1/LPL/ABHD2/ABHD12	4
GO:0046621	negative regulation of organ growth	4/1068	39/18722	0.180714169800291	0.345302287621235	TGFBR2/STK4/PAK1/RGS2	4
GO:0051154	negative regulation of striated muscle cell differentiation	4/1068	39/18722	0.180714169800291	0.345302287621235	YBX1/PAK1/RGS2/BHLHE41	4
GO:0090207	regulation of triglyceride metabolic process	4/1068	39/18722	0.180714169800291	0.345302287621235	APOE/C3/SORL1/NR1H3	4
GO:1902742	apoptotic process involved in development	4/1068	39/18722	0.180714169800291	0.345302287621235	SPI1/TNFRSF1B/TNFRSF1A/BAX	4
GO:0006637	acyl-CoA metabolic process	8/1068	96/18722	0.181513312710403	0.346583805868838	PPT1/PDK4/KYNU/ACOT9/ACSL1/ACAT1/ACSL4/HSD17B4	8
GO:0035383	thioester metabolic process	8/1068	96/18722	0.181513312710403	0.346583805868838	PPT1/PDK4/KYNU/ACOT9/ACSL1/ACAT1/ACSL4/HSD17B4	8
GO:0035296	regulation of tube diameter	11/1068	141/18722	0.181820140539429	0.346924143688387	APOE/GPX1/SOD2/SLC8A1/DOCK4/SCPEP1/RHOA/TBXAS1/KLF2/ROCK1/RGS2	11
GO:0097746	blood vessel diameter maintenance	11/1068	141/18722	0.181820140539429	0.346924143688387	APOE/GPX1/SOD2/SLC8A1/DOCK4/SCPEP1/RHOA/TBXAS1/KLF2/ROCK1/RGS2	11
GO:0016445	somatic diversification of immunoglobulins	6/1068	67/18722	0.1821189405014	0.347248693620337	SAMHD1/PTPRC/TGFB1/BCL6/STAT6/ERCC1	6
GO:1902117	positive regulation of organelle assembly	6/1068	67/18722	0.1821189405014	0.347248693620337	CCDC88A/LCP1/MSN/SDCBP/RHOA/NUP62	6
GO:0001573	ganglioside metabolic process	3/1068	26/18722	0.182902620209626	0.347637385928546	ST8SIA4/HEXA/GM2A	3
GO:0002026	regulation of the force of heart contraction	3/1068	26/18722	0.182902620209626	0.347637385928546	SLC8A1/GAA/ATP1A1	3
GO:0009435	NAD biosynthetic process	3/1068	26/18722	0.182902620209626	0.347637385928546	PARP9/KYNU/NAMPT	3
GO:0014829	vascular associated smooth muscle contraction	3/1068	26/18722	0.182902620209626	0.347637385928546	SLC8A1/DOCK4/RHOA	3
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	3/1068	26/18722	0.182902620209626	0.347637385928546	HLA-E/HLA-F/LAMP1	3
GO:0046697	decidualization	3/1068	26/18722	0.182902620209626	0.347637385928546	SPP1/CTSB/JUNB	3
GO:0071425	hematopoietic stem cell proliferation	3/1068	26/18722	0.182902620209626	0.347637385928546	RUNX1/ETV6/EIF2AK2	3
GO:0097186	amelogenesis	3/1068	26/18722	0.182902620209626	0.347637385928546	TCIRG1/FAM20C/RELT	3
GO:1902656	calcium ion import into cytosol	3/1068	26/18722	0.182902620209626	0.347637385928546	SLC8A1/PRNP/TRPM2	3
GO:0001541	ovarian follicle development	5/1068	53/18722	0.183454565168758	0.348195861291108	ARRB2/VEGFA/CEBPB/UBE3A/BAX	5
GO:0050819	negative regulation of coagulation	5/1068	53/18722	0.183454565168758	0.348195861291108	APOE/CD9/PLAU/SH2B3/SERPING1	5
GO:0097479	synaptic vesicle localization	5/1068	53/18722	0.183454565168758	0.348195861291108	LRRK2/BLOC1S1/BLOC1S2/PICALM/KIF5B	5
GO:1903202	negative regulation of oxidative stress-induced cell death	5/1068	53/18722	0.183454565168758	0.348195861291108	GPX1/SOD2/HIF1A/HGF/LRRK2	5
GO:2001020	regulation of response to DNA damage stimulus	16/1068	219/18722	0.186131511759613	0.351875868709051	CD74/IER3/CD44/SKIL/ACTR2/PARP9/WAS/BID/DTX3L/SPRED1/ERCC1/RNASEH2B/MCL1/ATM/DDX5/ZNF385A	16
GO:0046889	positive regulation of lipid biosynthetic process	7/1068	82/18722	0.186594116445236	0.351875868709051	APOE/CD74/CREBL2/LPGAT1/NR1H3/IL1B/ABCG1	7
GO:0007009	plasma membrane organization	11/1068	142/18722	0.187677471561272	0.351875868709051	CD9/CXCR4/PTPRC/PLSCR1/P2RX7/SERP1/STX4/ARL8B/GSN/FLOT1/PLEC	11
GO:0035150	regulation of tube size	11/1068	142/18722	0.187677471561272	0.351875868709051	APOE/GPX1/SOD2/SLC8A1/DOCK4/SCPEP1/RHOA/TBXAS1/KLF2/ROCK1/RGS2	11
GO:0001767	establishment of lymphocyte polarity	2/1068	14/18722	0.18839314023359	0.351875868709051	DOCK2/GSN	2
GO:0001921	positive regulation of receptor recycling	2/1068	14/18722	0.18839314023359	0.351875868709051	ARAP1/RAB29	2
GO:0002091	negative regulation of receptor internalization	2/1068	14/18722	0.18839314023359	0.351875868709051	SDCBP/RIN3	2
GO:0002829	negative regulation of type 2 immune response	2/1068	14/18722	0.18839314023359	0.351875868709051	BCL6/STAT6	2
GO:0006047	UDP-N-acetylglucosamine metabolic process	2/1068	14/18722	0.18839314023359	0.351875868709051	MGAT1/GNPDA1	2
GO:0006596	polyamine biosynthetic process	2/1068	14/18722	0.18839314023359	0.351875868709051	OAZ1/SAT1	2
GO:0009173	pyrimidine ribonucleoside monophosphate metabolic process	2/1068	14/18722	0.18839314023359	0.351875868709051	UPP1/DPYD	2
GO:0030213	hyaluronan biosynthetic process	2/1068	14/18722	0.18839314023359	0.351875868709051	TGFB1/IL1B	2
GO:0032966	negative regulation of collagen biosynthetic process	2/1068	14/18722	0.18839314023359	0.351875868709051	RAP1A/CIITA	2
GO:0033008	positive regulation of mast cell activation involved in immune response	2/1068	14/18722	0.18839314023359	0.351875868709051	SYK/FGR	2
GO:0034111	negative regulation of homotypic cell-cell adhesion	2/1068	14/18722	0.18839314023359	0.351875868709051	CD9/SH2B3	2
GO:0035563	positive regulation of chromatin binding	2/1068	14/18722	0.18839314023359	0.351875868709051	PARP9/DTX3L	2
GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	2/1068	14/18722	0.18839314023359	0.351875868709051	GPR34/PTAFR	2
GO:0036151	phosphatidylcholine acyl-chain remodeling	2/1068	14/18722	0.18839314023359	0.351875868709051	LPCAT2/NR1H3	2
GO:0038166	angiotensin-activated signaling pathway	2/1068	14/18722	0.18839314023359	0.351875868709051	AGTRAP/ROCK1	2
GO:0042921	glucocorticoid receptor signaling pathway	2/1068	14/18722	0.18839314023359	0.351875868709051	YWHAH/NR3C1	2
GO:0043173	nucleotide salvage	2/1068	14/18722	0.18839314023359	0.351875868709051	UPP1/HPRT1	2
GO:0043249	erythrocyte maturation	2/1068	14/18722	0.18839314023359	0.351875868709051	KLF2/PTBP3	2
GO:0043306	positive regulation of mast cell degranulation	2/1068	14/18722	0.18839314023359	0.351875868709051	SYK/FGR	2
GO:0043650	dicarboxylic acid biosynthetic process	2/1068	14/18722	0.18839314023359	0.351875868709051	KYNU/GLS	2
GO:0045006	DNA deamination	2/1068	14/18722	0.18839314023359	0.351875868709051	APOBEC3C/APOBEC3A	2
GO:0045837	negative regulation of membrane potential	2/1068	14/18722	0.18839314023359	0.351875868709051	BNIP3L/BAX	2
GO:0046049	UMP metabolic process	2/1068	14/18722	0.18839314023359	0.351875868709051	UPP1/DPYD	2
GO:0047484	regulation of response to osmotic stress	2/1068	14/18722	0.18839314023359	0.351875868709051	ARHGEF2/MICU1	2
GO:0050930	induction of positive chemotaxis	2/1068	14/18722	0.18839314023359	0.351875868709051	VEGFA/VEGFB	2
GO:0051589	negative regulation of neurotransmitter transport	2/1068	14/18722	0.18839314023359	0.351875868709051	RAP1A/SLC30A1	2
GO:0060841	venous blood vessel development	2/1068	14/18722	0.18839314023359	0.351875868709051	VEGFA/ENG	2
GO:0070141	response to UV-A	2/1068	14/18722	0.18839314023359	0.351875868709051	TIMP1/MMP2	2
GO:0070942	neutrophil mediated cytotoxicity	2/1068	14/18722	0.18839314023359	0.351875868709051	TREM1/MYD88	2
GO:0071285	cellular response to lithium ion	2/1068	14/18722	0.18839314023359	0.351875868709051	ADCY7/CEBPA	2
GO:0071415	cellular response to purine-containing compound	2/1068	14/18722	0.18839314023359	0.351875868709051	SLC8A1/TRPM2	2
GO:0071481	cellular response to X-ray	2/1068	14/18722	0.18839314023359	0.351875868709051	HAMP/ATM	2
GO:0072160	nephron tubule epithelial cell differentiation	2/1068	14/18722	0.18839314023359	0.351875868709051	STAT1/MEF2C	2
GO:0072531	pyrimidine-containing compound transmembrane transport	2/1068	14/18722	0.18839314023359	0.351875868709051	AQP9/SLC25A19	2
GO:0072540	T-helper 17 cell lineage commitment	2/1068	14/18722	0.18839314023359	0.351875868709051	IL6R/STAT3	2
GO:0098734	macromolecule depalmitoylation	2/1068	14/18722	0.18839314023359	0.351875868709051	PPT1/ABHD12	2
GO:0099188	postsynaptic cytoskeleton organization	2/1068	14/18722	0.18839314023359	0.351875868709051	ACTB/DBNL	2
GO:0099638	endosome to plasma membrane protein transport	2/1068	14/18722	0.18839314023359	0.351875868709051	RAB8A/RAB7A	2
GO:1901722	regulation of cell proliferation involved in kidney development	2/1068	14/18722	0.18839314023359	0.351875868709051	IL6R/EGR1	2
GO:1901857	positive regulation of cellular respiration	2/1068	14/18722	0.18839314023359	0.351875868709051	NUPR1/IFNAR1	2
GO:1905065	positive regulation of vascular associated smooth muscle cell differentiation	2/1068	14/18722	0.18839314023359	0.351875868709051	SOD2/ENG	2
GO:2001140	positive regulation of phospholipid transport	2/1068	14/18722	0.18839314023359	0.351875868709051	APOE/TMEM30A	2
GO:0071383	cellular response to steroid hormone stimulus	15/1068	204/18722	0.189102702546758	0.3530789560354	YWHAH/ZFP36L2/ZFP36/ZFP36L1/RHOA/ZMIZ1/DDIT4/JAK2/NCOR2/ABHD2/DDX5/PAK1/UBE3A/NR3C1/ATP1A1	15
GO:0035601	protein deacylation	9/1068	112/18722	0.189264370548754	0.353136425823333	PPT1/FLNA/VEGFA/JDP2/BCL6/SPRED1/LRRK2/ABHD12/SKI	9
GO:0048640	negative regulation of developmental growth	9/1068	112/18722	0.189264370548754	0.353136425823333	SPP1/LGMN/TGFBR2/ARHGAP4/STK4/CDKN1A/RTN4/PAK1/RGS2	9
GO:0006694	steroid biosynthetic process	13/1068	173/18722	0.189372769885908	0.353216545559751	APOE/TSPO/ASAH1/HSD17B11/CYP27A1/OSBPL1A/ACAA2/SRD5A3/PRKAG2/ABCG1/SCP2/EGR1/ATP1A1	13
GO:0030900	forebrain development	26/1068	379/18722	0.190321538160662	0.354863517593272	TYROBP/B2M/CXCR4/SLC8A1/ID2/PHACTR1/HIF1A/BCL2A1/FLNA/RHOA/NR4A2/ATF5/AXL/ZMIZ1/ZSWIM6/ITGAM/LRRK2/BTG2/HPRT1/LRP1/NUMB/RTN4/SKI/ARPC5/BAX/KIF5B	26
GO:0009988	cell-cell recognition	6/1068	68/18722	0.190845498912605	0.355471975192412	CD9/CD81/LGALS3/HAVCR2/MSN/DOCK2	6
GO:0032922	circadian regulation of gene expression	6/1068	68/18722	0.190845498912605	0.355471975192412	ID2/AHR/NAMPT/BHLHE40/EGR1/BHLHE41	6
GO:1901016	regulation of potassium ion transmembrane transporter activity	6/1068	68/18722	0.190845498912605	0.355471975192412	TREM2/KCNE3/ATP1B1/CAB39/KLHL24/ATP1B3	6
GO:0031111	negative regulation of microtubule polymerization or depolymerization	4/1068	40/18722	0.192398443440873	0.35750068898311	CIB1/ARHGEF2/APC/TAOK1	4
GO:0045022	early endosome to late endosome transport	4/1068	40/18722	0.192398443440873	0.35750068898311	MSN/FLNA/CHMP3/RAB7A	4
GO:0045777	positive regulation of blood pressure	4/1068	40/18722	0.192398443440873	0.35750068898311	CYBA/ID2/RHOA/WNK1	4
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	4/1068	40/18722	0.192398443440873	0.35750068898311	DUSP1/ATM/APC/DYNC1LI1	4
GO:0097352	autophagosome maturation	4/1068	40/18722	0.192398443440873	0.35750068898311	VMP1/LAMP2/MCOLN1/CHMP3	4
GO:2000142	regulation of DNA-templated transcription, initiation	4/1068	40/18722	0.192398443440873	0.35750068898311	JUN/MITF/ERCC1/SETX	4
GO:2000781	positive regulation of double-strand break repair	4/1068	40/18722	0.192398443440873	0.35750068898311	ACTR2/PARP9/WAS/DTX3L	4
GO:0090257	regulation of muscle system process	18/1068	252/18722	0.193199560790778	0.358865690198636	AIF1/HAMP/MEF2A/SLC8A1/DOCK4/RHOA/TNFRSF1B/KLF4/PTAFR/ATP1B1/CALM3/TNFRSF1A/ROCK1/GSTO1/PAK1/NR4A1/RGS2/ATP1A1	18
GO:0031050	dsRNA processing	5/1068	54/18722	0.193407571998068	0.358881450653912	TGFB1/NCOR2/STAT3/ADAR/DDX5	5
GO:0070918	production of small RNA involved in gene silencing by RNA	5/1068	54/18722	0.193407571998068	0.358881450653912	TGFB1/NCOR2/STAT3/ADAR/DDX5	5
GO:0072348	sulfur compound transport	5/1068	54/18722	0.193407571998068	0.358881450653912	MGST1/SLC25A19/LRRC8C/SLC6A6/MFSD12	5
GO:0050886	endocrine process	7/1068	83/18722	0.194526367862775	0.36083337263236	CYBA/CTSZ/RETN/RHOA/ATP6AP2/RAB8B/IL1B	7
GO:0003333	amino acid transmembrane transport	8/1068	98/18722	0.195986180962928	0.363416299819917	SLC7A7/SLC38A6/LRRC8C/SLC6A6/SFXN3/MFSD12/SLC1A3/RGS2	8
GO:0003272	endocardial cushion formation	3/1068	27/18722	0.197641142870916	0.365230002373789	ENG/TGFBR2/TGFBR1	3
GO:0009651	response to salt stress	3/1068	27/18722	0.197641142870916	0.365230002373789	ZFP36L1/BAX/MICU1	3
GO:0018126	protein hydroxylation	3/1068	27/18722	0.197641142870916	0.365230002373789	P4HA1/CRTAP/ERO1A	3
GO:0032781	positive regulation of ATPase activity	3/1068	27/18722	0.197641142870916	0.365230002373789	ATP1B1/ATP1B3/PFN1	3
GO:0033688	regulation of osteoblast proliferation	3/1068	27/18722	0.197641142870916	0.365230002373789	RHOA/HPSE/EIF2AK2	3
GO:0045830	positive regulation of isotype switching	3/1068	27/18722	0.197641142870916	0.365230002373789	PTPRC/TGFB1/STAT6	3
GO:0070861	regulation of protein exit from endoplasmic reticulum	3/1068	27/18722	0.197641142870916	0.365230002373789	CD81/SORL1/TMEM30A	3
GO:1901018	positive regulation of potassium ion transmembrane transporter activity	3/1068	27/18722	0.197641142870916	0.365230002373789	TREM2/ATP1B1/ATP1B3	3
GO:1902883	negative regulation of response to oxidative stress	3/1068	27/18722	0.197641142870916	0.365230002373789	HGF/MCTP1/LRRK2	3
GO:1902914	regulation of protein polyubiquitination	3/1068	27/18722	0.197641142870916	0.365230002373789	GABARAP/UBE2D1/XIAP	3
GO:0030198	extracellular matrix organization	21/1068	301/18722	0.198814744902817	0.367272976205272	CTSS/CST3/TGFBI/LCP1/RB1/TNFRSF1B/TGFB1/ENG/COLGALT1/RUNX1/ADAM8/MMP2/P4HA1/CRTAP/RGCC/LRP1/ERO1A/TGFBR1/TNFRSF1A/ADAM10/FLOT1	21
GO:0007612	learning	11/1068	144/18722	0.199645987917454	0.368682324025524	LGMN/FOS/PPT1/JUN/HIF1A/ACTR2/TLR2/ATXN1/BTG2/UBE3A/PIAS1	11
GO:0050810	regulation of steroid biosynthetic process	6/1068	69/18722	0.199728395519959	0.368708320980396	APOE/TSPO/ASAH1/ABCG1/EGR1/ATP1A1	6
GO:0007093	mitotic cell cycle checkpoint signaling	10/1068	129/18722	0.20156211255706	0.371966196770825	DUSP1/TAOK3/PLK3/CDKN1A/RPS27L/ATM/FOXN3/APC/DYNC1LI1/TAOK1	10
GO:0002088	lens development in camera-type eye	7/1068	84/18722	0.202589999683259	0.373607531883412	VIM/SKIL/MAF/TGFBR2/SPRED1/TGFBR1/SKI	7
GO:0010660	regulation of muscle cell apoptotic process	7/1068	84/18722	0.202589999683259	0.373607531883412	NUPR1/SOD2/HMOX1/ARRB2/JAK2/STK4/PTK2B	7
GO:0002244	hematopoietic progenitor cell differentiation	9/1068	114/18722	0.202904499255797	0.373670270797731	PLEK/SPI1/CSF1R/PTPRC/TGFB1/PTPN6/EIF2AK2/ADAR/FNIP1	9
GO:0021987	cerebral cortex development	9/1068	114/18722	0.202904499255797	0.373670270797731	PHACTR1/HIF1A/BCL2A1/FLNA/RHOA/ZMIZ1/LRP1/RTN4/BAX	9
GO:1903008	organelle disassembly	9/1068	114/18722	0.202904499255797	0.373670270797731	TSPO/HIF1A/VPS13C/PLK3/BNIP3L/GABARAP/CISD2/ATG3/KIF5B	9
GO:0043062	extracellular structure organization	21/1068	302/18722	0.202970267551547	0.373670270797731	CTSS/CST3/TGFBI/LCP1/RB1/TNFRSF1B/TGFB1/ENG/COLGALT1/RUNX1/ADAM8/MMP2/P4HA1/CRTAP/RGCC/LRP1/ERO1A/TGFBR1/TNFRSF1A/ADAM10/FLOT1	21
GO:0072001	renal system development	21/1068	302/18722	0.202970267551547	0.373670270797731	CTSH/STAT1/MEF2C/PECAM1/RHOA/VEGFA/PLXND1/PRDM1/NOTCH2/IL6R/LRRK2/PRKX/SGPL1/CNTRL/ACAT1/AP1B1/IQGAP1/TGFBR1/TMED10/BAX/EGR1	21
GO:0000045	autophagosome assembly	8/1068	99/18722	0.203395629377976	0.37370785064413	NUPR1/VMP1/TCIRG1/LRRK2/GABARAP/STX12/ATG3/RAB7A	8
GO:0003300	cardiac muscle hypertrophy	8/1068	99/18722	0.203395629377976	0.37370785064413	HAMP/MEF2A/TNFRSF1B/TNFRSF1A/ROCK1/PAK1/AKAP13/RGS2	8
GO:0051153	regulation of striated muscle cell differentiation	8/1068	99/18722	0.203395629377976	0.37370785064413	HAMP/MEF2C/ARRB2/YBX1/TGFB1/PAK1/RGS2/BHLHE41	8
GO:0043331	response to dsRNA	5/1068	55/18722	0.203544731846386	0.37370785064413	IFIT1/IRAK3/IFIH1/NFKBIA/FLOT1	5
GO:0044091	membrane biogenesis	5/1068	55/18722	0.203544731846386	0.37370785064413	STX4/SERINC1/PICALM/FLOT1/S100A10	5
GO:0046164	alcohol catabolic process	5/1068	55/18722	0.203544731846386	0.37370785064413	APOE/ALDH2/NUDT3/CYP27A1/SRD5A3	5
GO:0051898	negative regulation of protein kinase B signaling	5/1068	55/18722	0.203544731846386	0.37370785064413	ARRB2/CIB1/KLF4/SH2B3/PTPRJ	5
GO:0098900	regulation of action potential	5/1068	55/18722	0.203544731846386	0.37370785064413	CD36/FLNA/KCNAB2/KCNE3/CALM3	5
GO:0070296	sarcoplasmic reticulum calcium ion transport	4/1068	41/18722	0.204310677677024	0.374859033235369	CCL3/SLC8A1/CALM3/GSTO1	4
GO:1900371	regulation of purine nucleotide biosynthetic process	4/1068	41/18722	0.204310677677024	0.374859033235369	TMSB4X/TREM2/PDK4/STAT3	4
GO:0051961	negative regulation of nervous system development	11/1068	145/18722	0.205753161943485	0.377377315379689	SPP1/B2M/TREM2/TSPO/SORL1/YWHAH/TLR2/ARHGAP4/IL1B/RTN4/SKI	11
GO:0043467	regulation of generation of precursor metabolites and energy	10/1068	130/18722	0.208067126575111	0.379327593427677	NUPR1/FBP1/HIF1A/RHOA/P2RX7/DDIT4/PRKAG2/IFNAR1/STAT3/PPIF	10
GO:0070830	bicellular tight junction assembly	6/1068	70/18722	0.208760013558258	0.379327593427677	MTDH/PECAM1/PAK2/ROCK1/APC/RAB13	6
GO:0051650	establishment of vesicle localization	12/1068	161/18722	0.208931548133235	0.379327593427677	MYO5A/TCIRG1/MYO1F/TANC2/ITGA4/MYO1G/LRRK2/BLOC1S1/BLOC1S2/TMED10/PICALM/KIF5B	12
GO:0002070	epithelial cell maturation	2/1068	15/18722	0.209628406894243	0.379327593427677	HIF1A/CDKN1A	2
GO:0002836	positive regulation of response to tumor cell	2/1068	15/18722	0.209628406894243	0.379327593427677	HLA-DRB1/MR1	2
GO:0002839	positive regulation of immune response to tumor cell	2/1068	15/18722	0.209628406894243	0.379327593427677	HLA-DRB1/MR1	2
GO:0006089	lactate metabolic process	2/1068	15/18722	0.209628406894243	0.379327593427677	HIF1A/LDHA	2
GO:0006570	tyrosine metabolic process	2/1068	15/18722	0.209628406894243	0.379327593427677	IL4I1/FAH	2
GO:0006825	copper ion transport	2/1068	15/18722	0.209628406894243	0.379327593427677	SLC31A1/ATOX1	2
GO:0009163	nucleoside biosynthetic process	2/1068	15/18722	0.209628406894243	0.379327593427677	HPRT1/TK2	2
GO:0010940	positive regulation of necrotic cell death	2/1068	15/18722	0.209628406894243	0.379327593427677	TSPO/SLC6A6	2
GO:0014841	skeletal muscle satellite cell proliferation	2/1068	15/18722	0.209628406894243	0.379327593427677	JAK2/STAT3	2
GO:0014857	regulation of skeletal muscle cell proliferation	2/1068	15/18722	0.209628406894243	0.379327593427677	JAK2/STAT3	2
GO:0031269	pseudopodium assembly	2/1068	15/18722	0.209628406894243	0.379327593427677	APC/CDC42	2
GO:0034384	high-density lipoprotein particle clearance	2/1068	15/18722	0.209628406894243	0.379327593427677	APOE/TREM2	2
GO:0034404	nucleobase-containing small molecule biosynthetic process	2/1068	15/18722	0.209628406894243	0.379327593427677	HPRT1/TK2	2
GO:0035627	ceramide transport	2/1068	15/18722	0.209628406894243	0.379327593427677	PSAP/PLTP	2
GO:0042182	ketone catabolic process	2/1068	15/18722	0.209628406894243	0.379327593427677	KYNU/NQO2	2
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	2/1068	15/18722	0.209628406894243	0.379327593427677	CD74/CD44	2
GO:0045475	locomotor rhythm	2/1068	15/18722	0.209628406894243	0.379327593427677	ID2/EGR1	2
GO:0045986	negative regulation of smooth muscle contraction	2/1068	15/18722	0.209628406894243	0.379327593427677	DOCK4/RGS2	2
GO:0051284	positive regulation of sequestering of calcium ion	2/1068	15/18722	0.209628406894243	0.379327593427677	CALM3/GSTO1	2
GO:0051608	histamine transport	2/1068	15/18722	0.209628406894243	0.379327593427677	LYN/BTK	2
GO:0051775	response to redox state	2/1068	15/18722	0.209628406894243	0.379327593427677	ARHGDIB/ARHGDIA	2
GO:0055012	ventricular cardiac muscle cell differentiation	2/1068	15/18722	0.209628406894243	0.379327593427677	MEF2A/MEF2C	2
GO:0055091	phospholipid homeostasis	2/1068	15/18722	0.209628406894243	0.379327593427677	ABCG1/ABCA1	2
GO:0060253	negative regulation of glial cell proliferation	2/1068	15/18722	0.209628406894243	0.379327593427677	TSPO/SKI	2
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	2/1068	15/18722	0.209628406894243	0.379327593427677	SORL1/LRRK2	2
GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	2/1068	15/18722	0.209628406894243	0.379327593427677	HOMER3/PRNP	2
GO:0071380	cellular response to prostaglandin E stimulus	2/1068	15/18722	0.209628406894243	0.379327593427677	PTGER4/GNB1	2
GO:0106057	negative regulation of calcineurin-mediated signaling	2/1068	15/18722	0.209628406894243	0.379327593427677	HOMER3/PRNP	2
GO:1900029	positive regulation of ruffle assembly	2/1068	15/18722	0.209628406894243	0.379327593427677	CYFIP1/PFN1	2
GO:1901741	positive regulation of myoblast fusion	2/1068	15/18722	0.209628406894243	0.379327593427677	CD53/FLOT1	2
GO:1902902	negative regulation of autophagosome assembly	2/1068	15/18722	0.209628406894243	0.379327593427677	NUPR1/LRRK2	2
GO:1903543	positive regulation of exosomal secretion	2/1068	15/18722	0.209628406894243	0.379327593427677	SDCBP/RAB7A	2
GO:1905168	positive regulation of double-strand break repair via homologous recombination	2/1068	15/18722	0.209628406894243	0.379327593427677	ACTR2/WAS	2
GO:1905288	vascular associated smooth muscle cell apoptotic process	2/1068	15/18722	0.209628406894243	0.379327593427677	SOD2/STK4	2
GO:1905459	regulation of vascular associated smooth muscle cell apoptotic process	2/1068	15/18722	0.209628406894243	0.379327593427677	SOD2/STK4	2
GO:2000104	negative regulation of DNA-dependent DNA replication	2/1068	15/18722	0.209628406894243	0.379327593427677	SLFN11/BCL6	2
GO:2001138	regulation of phospholipid transport	2/1068	15/18722	0.209628406894243	0.379327593427677	APOE/TMEM30A	2
GO:0090630	activation of GTPase activity	9/1068	115/18722	0.209873167682675	0.379643182304967	GPR65/CORO1C/RHOG/ABR/TBC1D2/PTK2B/ARHGAP24/TBC1D9B/RCC2	9
GO:0009142	nucleoside triphosphate biosynthetic process	7/1068	85/18722	0.210779564390271	0.381027313048544	TMSB4X/TREM2/TGFB1/ATP6V1A/IMPDH1/PRKAG2/STAT3	7
GO:0044774	mitotic DNA integrity checkpoint signaling	7/1068	85/18722	0.210779564390271	0.381027313048544	TAOK3/PLK3/CDKN1A/RPS27L/ATM/FOXN3/TAOK1	7
GO:0045229	external encapsulating structure organization	21/1068	304/18722	0.211406020160612	0.3820317765528	CTSS/CST3/TGFBI/LCP1/RB1/TNFRSF1B/TGFB1/ENG/COLGALT1/RUNX1/ADAM8/MMP2/P4HA1/CRTAP/RGCC/LRP1/ERO1A/TGFBR1/TNFRSF1A/ADAM10/FLOT1	21
GO:0007043	cell-cell junction assembly	11/1068	146/18722	0.211939491473122	0.382867591559747	CD9/MTDH/ACTB/PECAM1/RHOA/TLN1/IL1B/PAK2/ROCK1/APC/RAB13	11
GO:0000303	response to superoxide	3/1068	28/18722	0.212651967523499	0.383256518622846	SOD2/CD36/UCP2	3
GO:0001945	lymph vessel development	3/1068	28/18722	0.212651967523499	0.383256518622846	SYK/VEGFA/VASH1	3
GO:0006516	glycoprotein catabolic process	3/1068	28/18722	0.212651967523499	0.383256518622846	CST3/HPSE/MAN1A1	3
GO:0032958	inositol phosphate biosynthetic process	3/1068	28/18722	0.212651967523499	0.383256518622846	PLEK/PTAFR/PTK2B	3
GO:0044331	cell-cell adhesion mediated by cadherin	3/1068	28/18722	0.212651967523499	0.383256518622846	VEGFA/RGCC/FLOT1	3
GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	3/1068	28/18722	0.212651967523499	0.383256518622846	SH2B3/PARP14/SOCS3	3
GO:0090344	negative regulation of cell aging	3/1068	28/18722	0.212651967523499	0.383256518622846	YBX1/NAMPT/BCL6	3
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	5/1068	56/18722	0.213854422648481	0.384396557165624	ZFP36L2/ZFP36/ZFP36L1/PABPC1/BTG2	5
GO:0006687	glycosphingolipid metabolic process	5/1068	56/18722	0.213854422648481	0.384396557165624	ST8SIA4/GALC/HEXA/BAX/GM2A	5
GO:0022029	telencephalon cell migration	5/1068	56/18722	0.213854422648481	0.384396557165624	CXCR4/RHOA/ZMIZ1/LRRK2/RTN4	5
GO:0031122	cytoplasmic microtubule organization	5/1068	56/18722	0.213854422648481	0.384396557165624	CCDC88A/RHOA/CIB1/PLK3/KPNB1	5
GO:0048255	mRNA stabilization	5/1068	56/18722	0.213854422648481	0.384396557165624	ZFP36/SLC11A1/YBX1/PABPC1/MYD88	5
GO:0051058	negative regulation of small GTPase mediated signal transduction	5/1068	56/18722	0.213854422648481	0.384396557165624	FBP1/TIMP2/BCL6/NUP62/ARHGAP24	5
GO:0051784	negative regulation of nuclear division	5/1068	56/18722	0.213854422648481	0.384396557165624	DUSP1/ATM/PRKAR1A/APC/DYNC1LI1	5
GO:0071385	cellular response to glucocorticoid stimulus	5/1068	56/18722	0.213854422648481	0.384396557165624	ZFP36L2/ZFP36/ZFP36L1/DDIT4/NR3C1	5
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	10/1068	131/18722	0.214658275284334	0.385712971506582	SORL1/SKIL/HSPA1A/SPRED1/LRP1/HTRA1/ADAM17/UBE2D1/SKI/UBE2D3	10
GO:0000266	mitochondrial fission	4/1068	42/18722	0.216431311154986	0.38709425090895	STAT2/LRRK2/RALA/DDHD1	4
GO:0000413	protein peptidyl-prolyl isomerization	4/1068	42/18722	0.216431311154986	0.38709425090895	FKBP15/FKBP5/RANBP2/PPIF	4
GO:0009124	nucleoside monophosphate biosynthetic process	4/1068	42/18722	0.216431311154986	0.38709425090895	UPP1/IMPDH1/HPRT1/TK2	4
GO:0030808	regulation of nucleotide biosynthetic process	4/1068	42/18722	0.216431311154986	0.38709425090895	TMSB4X/TREM2/PDK4/STAT3	4
GO:0032467	positive regulation of cytokinesis	4/1068	42/18722	0.216431311154986	0.38709425090895	RHOA/NUP62/CDC42/CHMP3	4
GO:0033574	response to testosterone	4/1068	42/18722	0.216431311154986	0.38709425090895	SPP1/TSPO/DUSP1/MSN	4
GO:0035019	somatic stem cell population maintenance	4/1068	42/18722	0.216431311154986	0.38709425090895	ZFP36L2/SPI1/SKI/KLF10	4
GO:0043507	positive regulation of JUN kinase activity	4/1068	42/18722	0.216431311154986	0.38709425090895	TAOK3/SYK/PTK2B/PAK1	4
GO:0055090	acylglycerol homeostasis	4/1068	42/18722	0.216431311154986	0.38709425090895	APOE/IL18/LPL/NR1H3	4
GO:0070328	triglyceride homeostasis	4/1068	42/18722	0.216431311154986	0.38709425090895	APOE/IL18/LPL/NR1H3	4
GO:0072595	maintenance of protein localization in organelle	4/1068	42/18722	0.216431311154986	0.38709425090895	TSPO/CHCHD10/SP100/MORC3	4
GO:0090317	negative regulation of intracellular protein transport	4/1068	42/18722	0.216431311154986	0.38709425090895	CD36/SP100/MDFIC/LRRK2	4
GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	4/1068	42/18722	0.216431311154986	0.38709425090895	DUSP1/ATM/APC/DYNC1LI1	4
GO:1903432	regulation of TORC1 signaling	4/1068	42/18722	0.216431311154986	0.38709425090895	RRAGD/GPR137B/SESN3/ATM	4
GO:0030518	intracellular steroid hormone receptor signaling pathway	9/1068	116/18722	0.21693658932673	0.387692577367657	YWHAH/RHOA/ZMIZ1/JAK2/NCOR2/DDX5/PAK1/UBE3A/NR3C1	9
GO:0098732	macromolecule deacylation	9/1068	116/18722	0.21693658932673	0.387692577367657	PPT1/FLNA/VEGFA/JDP2/BCL6/SPRED1/LRRK2/ABHD12/SKI	9
GO:0035725	sodium ion transmembrane transport	13/1068	178/18722	0.216981390594945	0.387692577367657	FXYD5/YWHAH/SLC8A1/SLC4A7/TRPM2/SLC6A6/ATP1B1/GLRX/KLHL24/WNK1/KIF5B/ATP1B3/ATP1A1	13
GO:0003208	cardiac ventricle morphogenesis	6/1068	71/18722	0.217932576030881	0.389134407763942	HIF1A/MEF2C/TGFB1/ENG/TGFBR2/TGFBR1	6
GO:0008344	adult locomotory behavior	6/1068	71/18722	0.217932576030881	0.389134407763942	CSTB/PPT1/ARRB2/NR4A2/PBX3/ABHD12	6
GO:0015711	organic anion transport	24/1068	354/18722	0.218010374176598	0.389144551457798	PSAP/SLC11A1/SLC7A7/CD36/SLCO2B1/SLC16A3/SYK/MGST1/SLC25A24/SLC4A7/SLC38A6/AQP9/SLC25A19/ABCC3/LRRC8C/MPC1/CYB5R4/SLC6A6/SFXN3/SLC2A3/MFSD12/IL1B/SLC1A3/RGS2	24
GO:1903509	liposaccharide metabolic process	8/1068	101/18722	0.218540139749775	0.389961175294241	GAL3ST4/ST8SIA4/AOAH/GALC/SCCPDH/HEXA/BAX/GM2A	8
GO:0035264	multicellular organism growth	10/1068	132/18722	0.221332887780493	0.394813971062327	LGMN/ZFP36L1/ATF5/NOTCH2/KLF2/STAT5A/ERCC1/SGPL1/STAT3/PLEC	10
GO:0006790	sulfur compound metabolic process	23/1068	339/18722	0.222904972947573	0.397486858567451	GPX1/PPT1/DSE/PDK4/GAL3ST4/KYNU/SLC25A19/CSGALNACT2/STAT5A/ACOT9/ACSL1/GPX4/MGST2/GNS/PAPSS1/AKR1A1/ACAT1/MAT2A/GSTO1/CLIC1/ACSL4/HSD17B4/B3GNT2	23
GO:0016447	somatic recombination of immunoglobulin gene segments	5/1068	57/18722	0.224324882392854	0.399622669327117	PTPRC/TGFB1/BCL6/STAT6/ERCC1	5
GO:0051205	protein insertion into membrane	5/1068	57/18722	0.224324882392854	0.399622669327117	EMC3/TRAM1/OXA1L/BAX/CAMLG	5
GO:0061005	cell differentiation involved in kidney development	5/1068	57/18722	0.224324882392854	0.399622669327117	STAT1/MEF2C/NOTCH2/PRKX/IQGAP1	5
GO:0035148	tube formation	11/1068	148/18722	0.224540867697358	0.399743491288334	HIF1A/VEGFA/ST14/TGFB1/VASP/STK4/RALA/PRKACB/SKI/SDCCAG8/PFN1	11
GO:0070507	regulation of microtubule cytoskeleton organization	11/1068	148/18722	0.224540867697358	0.399743491288334	RHOA/CIB1/HSPA1A/ARHGEF2/RAC1/ROCK1/APC/PAK1/NUP62/TAOK1/CHMP1B	11
GO:0060485	mesenchyme development	20/1068	291/18722	0.224918045748176	0.400282907274788	S100A4/STAT1/HIF1A/MEF2C/ZFP36L1/HGF/FLNA/SDCBP/CORO1C/GLIPR2/TGFB1/ENG/TGFBR2/SPRED1/IL1B/RGCC/DDX5/TGFBR1/RTN4/ROCK1	20
GO:0006672	ceramide metabolic process	8/1068	102/18722	0.226266710204016	0.402152558715702	ASAH1/ST8SIA4/GALC/SGPL1/HEXA/PLA2G15/ACER3/GM2A	8
GO:0014897	striated muscle hypertrophy	8/1068	102/18722	0.226266710204016	0.402152558715702	HAMP/MEF2A/TNFRSF1B/TNFRSF1A/ROCK1/PAK1/AKAP13/RGS2	8
GO:1902749	regulation of cell cycle G2/M phase transition	8/1068	102/18722	0.226266710204016	0.402152558715702	TAOK3/ATF5/CDKN1A/RNASEH2B/ATM/FOXN3/TAOK1/RCC2	8
GO:1904063	negative regulation of cation transmembrane transport	8/1068	102/18722	0.226266710204016	0.402152558715702	HAMP/KCNE3/SLC30A1/CALM3/CAB39/GSTO1/RGS2/PPIF	8
GO:0050709	negative regulation of protein secretion	6/1068	72/18722	0.227238170413259	0.403275913052697	APOE/UCP2/RSAD2/NR1H3/RHBDF2/IL1B	6
GO:1905818	regulation of chromosome separation	6/1068	72/18722	0.227238170413259	0.403275913052697	DUSP1/RB1/PLSCR1/ATM/APC/DYNC1LI1	6
GO:1900182	positive regulation of protein localization to nucleus	7/1068	87/18722	0.227514052369164	0.403275913052697	FLNA/PARP9/TGFB1/DTX3L/JAK2/HCLS1/PIK3R1	7
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	3/1068	29/18722	0.227896519824136	0.403275913052697	ZFP36/PABPC1/BTG2	3
GO:0000305	response to oxygen radical	3/1068	29/18722	0.227896519824136	0.403275913052697	SOD2/CD36/UCP2	3
GO:0019359	nicotinamide nucleotide biosynthetic process	3/1068	29/18722	0.227896519824136	0.403275913052697	PARP9/KYNU/NAMPT	3
GO:0019363	pyridine nucleotide biosynthetic process	3/1068	29/18722	0.227896519824136	0.403275913052697	PARP9/KYNU/NAMPT	3
GO:0062098	regulation of programmed necrotic cell death	3/1068	29/18722	0.227896519824136	0.403275913052697	NUPR1/ASAH1/ARHGEF2	3
GO:0072539	T-helper 17 cell differentiation	3/1068	29/18722	0.227896519824136	0.403275913052697	IL6R/STAT3/NFKBIZ	3
GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	3/1068	29/18722	0.227896519824136	0.403275913052697	CD74/CD44/ZNF385A	3
GO:0015698	inorganic anion transport	13/1068	180/18722	0.228482403975666	0.403275913052697	TSPO/SLC11A1/SLC4A7/PRNP/PTAFR/ABCC3/LRRC8C/TTYH3/SLC37A2/CEBPB/SLC1A3/CLIC1/CLCN7	13
GO:0033046	negative regulation of sister chromatid segregation	4/1068	43/18722	0.228740811693896	0.403275913052697	DUSP1/ATM/APC/DYNC1LI1	4
GO:0033048	negative regulation of mitotic sister chromatid segregation	4/1068	43/18722	0.228740811693896	0.403275913052697	DUSP1/ATM/APC/DYNC1LI1	4
GO:0033173	calcineurin-NFAT signaling cascade	4/1068	43/18722	0.228740811693896	0.403275913052697	CLEC7A/HOMER3/CIB1/PRNP	4
GO:0045776	negative regulation of blood pressure	4/1068	43/18722	0.228740811693896	0.403275913052697	SOD2/SCPEP1/PTAFR/PRCP	4
GO:0045840	positive regulation of mitotic nuclear division	4/1068	43/18722	0.228740811693896	0.403275913052697	RB1/IL1B/RGCC/NUP62	4
GO:0060443	mammary gland morphogenesis	4/1068	43/18722	0.228740811693896	0.403275913052697	CSF1R/TGFBR2/STAT6/BAX	4
GO:0061383	trabecula morphogenesis	4/1068	43/18722	0.228740811693896	0.403275913052697	RHOA/ENG/MMP2/TGFBR1	4
GO:0120178	steroid hormone biosynthetic process	4/1068	43/18722	0.228740811693896	0.403275913052697	TSPO/HSD17B11/SRD5A3/EGR1	4
GO:2000816	negative regulation of mitotic sister chromatid separation	4/1068	43/18722	0.228740811693896	0.403275913052697	DUSP1/ATM/APC/DYNC1LI1	4
GO:0007548	sex differentiation	19/1068	276/18722	0.229992181715935	0.403275913052697	NUPR1/LHFPL2/ARRB2/FLNA/RETN/AXL/MGST1/VEGFA/TNFSF10/ERCC1/SGPL1/FNDC3A/CEBPB/ARID4A/TGFBR1/UBE3A/BAX/HSD17B4/RAB13	19
GO:0030258	lipid modification	15/1068	212/18722	0.230231173240388	0.403275913052697	APOE/APOC1/PLA2G7/SOAT1/PDK4/ALOX5/ACAA2/INPP5D/PRKAG2/MTMR6/ABCG1/ACAT1/CPT1A/SCP2/HSD17B4	15
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	2/1068	16/18722	0.231083973898988	0.403275913052697	CTSZ/ATP6AP2	2
GO:0002566	somatic diversification of immune receptors via somatic mutation	2/1068	16/18722	0.231083973898988	0.403275913052697	SAMHD1/ADAR	2
GO:0002693	positive regulation of cellular extravasation	2/1068	16/18722	0.231083973898988	0.403275913052697	PTAFR/ADAM8	2
GO:0002713	negative regulation of B cell mediated immunity	2/1068	16/18722	0.231083973898988	0.403275913052697	PTPN6/BCL6	2
GO:0002890	negative regulation of immunoglobulin mediated immune response	2/1068	16/18722	0.231083973898988	0.403275913052697	PTPN6/BCL6	2
GO:0006206	pyrimidine nucleobase metabolic process	2/1068	16/18722	0.231083973898988	0.403275913052697	TYMP/DPYD	2
GO:0006857	oligopeptide transport	2/1068	16/18722	0.231083973898988	0.403275913052697	SLC15A3/MGST1	2
GO:0009415	response to water	2/1068	16/18722	0.231083973898988	0.403275913052697	CD9/PLEC	2
GO:0010649	regulation of cell communication by electrical coupling	2/1068	16/18722	0.231083973898988	0.403275913052697	SLC8A1/CALM3	2
GO:0014819	regulation of skeletal muscle contraction	2/1068	16/18722	0.231083973898988	0.403275913052697	GSTO1/NR4A1	2
GO:0030033	microvillus assembly	2/1068	16/18722	0.231083973898988	0.403275913052697	FXYD5/RAP2A	2
GO:0030540	female genitalia development	2/1068	16/18722	0.231083973898988	0.403275913052697	AXL/BAX	2
GO:0031268	pseudopodium organization	2/1068	16/18722	0.231083973898988	0.403275913052697	APC/CDC42	2
GO:0034393	positive regulation of smooth muscle cell apoptotic process	2/1068	16/18722	0.231083973898988	0.403275913052697	SOD2/STK4	2
GO:0044065	regulation of respiratory system process	2/1068	16/18722	0.231083973898988	0.403275913052697	GLS/PBX3	2
GO:0045838	positive regulation of membrane potential	2/1068	16/18722	0.231083973898988	0.403275913052697	BID/GLRX	2
GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	2/1068	16/18722	0.231083973898988	0.403275913052697	APOBEC3C/APOBEC3A	2
GO:0046037	GMP metabolic process	2/1068	16/18722	0.231083973898988	0.403275913052697	IMPDH1/HPRT1	2
GO:0048311	mitochondrion distribution	2/1068	16/18722	0.231083973898988	0.403275913052697	MEF2A/LRRK2	2
GO:0048385	regulation of retinoic acid receptor signaling pathway	2/1068	16/18722	0.231083973898988	0.403275913052697	KLF2/DHRS3	2
GO:0050862	positive regulation of T cell receptor signaling pathway	2/1068	16/18722	0.231083973898988	0.403275913052697	CD81/RAB29	2
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	2/1068	16/18722	0.231083973898988	0.403275913052697	CXCR4/ARRB2	2
GO:0051238	sequestering of metal ion	2/1068	16/18722	0.231083973898988	0.403275913052697	FTL/FTH1	2
GO:0072109	glomerular mesangium development	2/1068	16/18722	0.231083973898988	0.403275913052697	IL6R/EGR1	2
GO:0090231	regulation of spindle checkpoint	2/1068	16/18722	0.231083973898988	0.403275913052697	DUSP1/DYNC1LI1	2
GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	2/1068	16/18722	0.231083973898988	0.403275913052697	DUSP1/DYNC1LI1	2
GO:0099633	protein localization to postsynaptic specialization membrane	2/1068	16/18722	0.231083973898988	0.403275913052697	RAP1A/ADAM10	2
GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	2/1068	16/18722	0.231083973898988	0.403275913052697	RAP1A/ADAM10	2
GO:1901201	regulation of extracellular matrix assembly	2/1068	16/18722	0.231083973898988	0.403275913052697	TGFB1/RGCC	2
GO:1902931	negative regulation of alcohol biosynthetic process	2/1068	16/18722	0.231083973898988	0.403275913052697	APOE/PLEK	2
GO:1903236	regulation of leukocyte tethering or rolling	2/1068	16/18722	0.231083973898988	0.403275913052697	PTAFR/ITGA4	2
GO:1903504	regulation of mitotic spindle checkpoint	2/1068	16/18722	0.231083973898988	0.403275913052697	DUSP1/DYNC1LI1	2
GO:1905874	regulation of postsynaptic density organization	2/1068	16/18722	0.231083973898988	0.403275913052697	ABI3/LILRB2	2
GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	2/1068	16/18722	0.231083973898988	0.403275913052697	PARP9/DTX3L	2
GO:0006413	translational initiation	9/1068	118/18722	0.231334226888397	0.403451676887457	EIF4EBP1/MIF4GD/EIF2AK2/EIF4G3/PPP1R15A/EIF2S3/DNAJC3/EIF1/UHMK1	9
GO:0007613	memory	9/1068	118/18722	0.231334226888397	0.403451676887457	APOE/TREM2/SGK1/LGMN/PRNP/ATXN1/NQO2/CEBPB/PJA2	9
GO:0003279	cardiac septum development	8/1068	103/18722	0.234090337809873	0.407994658534262	PLXND1/ENG/TGFBR2/PRDM1/NOTCH2/CNTRL/DHRS3/TGFBR1	8
GO:1905037	autophagosome organization	8/1068	103/18722	0.234090337809873	0.407994658534262	NUPR1/VMP1/TCIRG1/LRRK2/GABARAP/STX12/ATG3/RAB7A	8
GO:0008277	regulation of G protein-coupled receptor signaling pathway	10/1068	134/18722	0.234921477737536	0.408559196536178	RGS1/C3/PLEK/RGS10/ARRB2/GNAI2/RGS18/GIT2/ROCK1/RGS2	10
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	10/1068	134/18722	0.234921477737536	0.408559196536178	SDCBP/HSPA1A/PLK3/LRRK2/GABARAP/CEBPA/HERPUD1/PIAS1/CAMLG/SUMO2	10
GO:0035904	aorta development	5/1068	58/18722	0.234944252567042	0.408559196536178	PLXND1/ENG/PRDM1/CNTRL/LRP1	5
GO:0042743	hydrogen peroxide metabolic process	5/1068	58/18722	0.234944252567042	0.408559196536178	GPX1/CYBA/SOD2/STAT3/RAC1	5
GO:0086065	cell communication involved in cardiac conduction	5/1068	58/18722	0.234944252567042	0.408559196536178	SLC8A1/FLNA/ATP1B1/CALM3/ATP1A1	5
GO:0097035	regulation of membrane lipid distribution	5/1068	58/18722	0.234944252567042	0.408559196536178	PLSCR1/P2RX7/ABCG1/ABCA1/TMEM30A	5
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	5/1068	58/18722	0.234944252567042	0.408559196536178	NUPR1/SKIL/BID/MCL1/BAX	5
GO:0001843	neural tube closure	7/1068	88/18722	0.236047474831596	0.410081189372599	ST14/TGFB1/VASP/RALA/PRKACB/SKI/PFN1	7
GO:0031110	regulation of microtubule polymerization or depolymerization	7/1068	88/18722	0.236047474831596	0.410081189372599	CIB1/HSPA1A/ARHGEF2/RAC1/APC/PAK1/TAOK1	7
GO:0050779	RNA destabilization	7/1068	88/18722	0.236047474831596	0.410081189372599	ZFP36L2/ZFP36/ZFP36L1/TNFRSF1B/PABPC1/BTG2/ROCK1	7
GO:1904427	positive regulation of calcium ion transmembrane transport	6/1068	73/18722	0.236668772764347	0.411028225888772	VMP1/KCNE3/ATP1B1/CALM3/GSTO1/BAX	6
GO:0006775	fat-soluble vitamin metabolic process	4/1068	44/18722	0.241219758152077	0.418797237769822	LGMN/PLTP/CYP27A1/VKORC1	4
GO:0042157	lipoprotein metabolic process	10/1068	135/18722	0.241829784354308	0.419623187583592	APOE/APOC1/CTSD/GLUL/OLR1/PPT1/APOL6/ABHD12/LRP1/ABCA1	10
GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	8/1068	104/18722	0.242006552957772	0.419623187583592	FPR3/GPR65/C5AR1/C3AR1/LPAR6/FPR1/GNA15/GNB1	8
GO:0022600	digestive system process	8/1068	104/18722	0.242006552957772	0.419623187583592	TYMP/HAMP/SGK1/SNX10/CD36/TLR4/NR1H3/WNK1	8
GO:1901890	positive regulation of cell junction assembly	8/1068	104/18722	0.242006552957772	0.419623187583592	LIMS1/VEGFA/PTPRJ/RAC1/IQGAP1/ROCK1/FLOT1/S100A10	8
GO:0007176	regulation of epidermal growth factor-activated receptor activity	3/1068	30/18722	0.243337431693925	0.420310109289507	HBEGF/NCF1/ADAM17	3
GO:0009072	aromatic amino acid family metabolic process	3/1068	30/18722	0.243337431693925	0.420310109289507	IL4I1/KYNU/FAH	3
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	3/1068	30/18722	0.243337431693925	0.420310109289507	SLC8A1/CALM3/GSTO1	3
GO:0015721	bile acid and bile salt transport	3/1068	30/18722	0.243337431693925	0.420310109289507	SLCO2B1/AQP9/ABCC3	3
GO:0034390	smooth muscle cell apoptotic process	3/1068	30/18722	0.243337431693925	0.420310109289507	SOD2/ARRB2/STK4	3
GO:0034391	regulation of smooth muscle cell apoptotic process	3/1068	30/18722	0.243337431693925	0.420310109289507	SOD2/ARRB2/STK4	3
GO:0045070	positive regulation of viral genome replication	3/1068	30/18722	0.243337431693925	0.420310109289507	IFIT1/PABPC1/ADAR	3
GO:0045940	positive regulation of steroid metabolic process	3/1068	30/18722	0.243337431693925	0.420310109289507	APOE/APOC1/ABCG1	3
GO:0045948	positive regulation of translational initiation	3/1068	30/18722	0.243337431693925	0.420310109289507	PPP1R15A/DNAJC3/UHMK1	3
GO:0090151	establishment of protein localization to mitochondrial membrane	3/1068	30/18722	0.243337431693925	0.420310109289507	CALM3/OXA1L/BAX	3
GO:0140058	neuron projection arborization	3/1068	30/18722	0.243337431693925	0.420310109289507	PHACTR1/LRRK2/ROCK1	3
GO:1900101	regulation of endoplasmic reticulum unfolded protein response	3/1068	30/18722	0.243337431693925	0.420310109289507	PPP1R15A/BAX/PIK3R1	3
GO:0071333	cellular response to glucose stimulus	11/1068	151/18722	0.243980389987377	0.421285818999004	HLA-DRB1/LGALS1/CYBA/TREM2/HIF1A/UCP2/RAC1/ABCG1/LRP1/STX4/KIF5B	11
GO:0060606	tube closure	7/1068	89/18722	0.244683857642222	0.422365353754776	ST14/TGFB1/VASP/RALA/PRKACB/SKI/PFN1	7
GO:0033013	tetrapyrrole metabolic process	5/1068	59/18722	0.245700619545343	0.423849278473999	TSPO/HMOX1/SLCO2B1/BLVRB/BLVRA	5
GO:0090303	positive regulation of wound healing	5/1068	59/18722	0.245700619545343	0.423849278473999	CXCR4/CLEC7A/CD36/HBEGF/HPSE	5
GO:0072655	establishment of protein localization to mitochondrion	9/1068	120/18722	0.246069722734134	0.424331842631637	TSPO/BID/LRRK2/BNIP3L/RALA/CALM3/OXA1L/BAX/UBE2D3	9
GO:0120192	tight junction assembly	6/1068	74/18722	0.246216271178587	0.424331842631637	MTDH/PECAM1/PAK2/ROCK1/APC/RAB13	6
GO:1901568	fatty acid derivative metabolic process	6/1068	74/18722	0.246216271178587	0.424331842631637	PPT1/ALOX5/ACSL1/ACAT1/ACSL4/HSD17B4	6
GO:0043401	steroid hormone mediated signaling pathway	10/1068	136/18722	0.248810222295883	0.428665376599165	YWHAH/RHOA/ZMIZ1/JAK2/NCOR2/ABHD2/DDX5/PAK1/UBE3A/NR3C1	10
GO:0021915	neural tube development	11/1068	152/18722	0.25059402796642	0.431450686460294	HIF1A/ZFP36L1/ATP6AP2/ST14/TGFB1/VASP/STK4/RALA/PRKACB/SKI/PFN1	11
GO:2000241	regulation of reproductive process	12/1068	168/18722	0.251666084013253	0.431450686460294	TIMP1/NUPR1/LHFPL2/DUSP1/ARHGDIB/RETN/CIB1/VEGFA/PTAFR/STK4/PRKAR1A/PRKACB	12
GO:0055001	muscle cell development	13/1068	184/18722	0.252196613294761	0.431450686460294	GPX1/HAMP/MEF2A/SLC8A1/VEGFA/ENG/PRKAR1A/PAK1/SKI/FLII/AKAP13/RGS2/PLEC	13
GO:0099003	vesicle-mediated transport in synapse	14/1068	200/18722	0.252307595996452	0.431450686460294	ACTB/RAP1A/LRRK2/ITSN2/CYFIP1/NUMB/STX4/CALM3/ROCK1/CANX/FCHO2/PICALM/ARF6/RAB8A	14
GO:0001780	neutrophil homeostasis	2/1068	17/18722	0.252665709639461	0.431450686460294	AXL/SH2B3	2
GO:0007625	grooming behavior	2/1068	17/18722	0.252665709639461	0.431450686460294	PPT1/HPRT1	2
GO:0008340	determination of adult lifespan	2/1068	17/18722	0.252665709639461	0.431450686460294	INPP5D/LRRK2	2
GO:0009084	glutamine family amino acid biosynthetic process	2/1068	17/18722	0.252665709639461	0.431450686460294	GLUL/GLS	2
GO:0010224	response to UV-B	2/1068	17/18722	0.252665709639461	0.431450686460294	CRIP1/CDKN1A	2
GO:0014856	skeletal muscle cell proliferation	2/1068	17/18722	0.252665709639461	0.431450686460294	JAK2/STAT3	2
GO:0020027	hemoglobin metabolic process	2/1068	17/18722	0.252665709639461	0.431450686460294	HIF1A/KLF4	2
GO:0030002	cellular anion homeostasis	2/1068	17/18722	0.252665709639461	0.431450686460294	TBXAS1/KCNE3	2
GO:0033623	regulation of integrin activation	2/1068	17/18722	0.252665709639461	0.431450686460294	PLEK/PTGER4	2
GO:0042339	keratan sulfate metabolic process	2/1068	17/18722	0.252665709639461	0.431450686460294	GNS/B3GNT2	2
GO:0044539	long-chain fatty acid import into cell	2/1068	17/18722	0.252665709639461	0.431450686460294	CD36/ACSL1	2
GO:0055064	chloride ion homeostasis	2/1068	17/18722	0.252665709639461	0.431450686460294	TBXAS1/KCNE3	2
GO:0055083	monovalent inorganic anion homeostasis	2/1068	17/18722	0.252665709639461	0.431450686460294	TBXAS1/KCNE3	2
GO:0061952	midbody abscission	2/1068	17/18722	0.252665709639461	0.431450686460294	CHMP3/CHMP1B	2
GO:0070206	protein trimerization	2/1068	17/18722	0.252665709639461	0.431450686460294	CD74/ALOX5AP	2
GO:0070293	renal absorption	2/1068	17/18722	0.252665709639461	0.431450686460294	SGK1/GSN	2
GO:0071816	tail-anchored membrane protein insertion into ER membrane	2/1068	17/18722	0.252665709639461	0.431450686460294	EMC3/CAMLG	2
GO:0090036	regulation of protein kinase C signaling	2/1068	17/18722	0.252665709639461	0.431450686460294	VEGFA/MYADM	2
GO:0090083	regulation of inclusion body assembly	2/1068	17/18722	0.252665709639461	0.431450686460294	SORL1/HSPA1A	2
GO:0140354	lipid import into cell	2/1068	17/18722	0.252665709639461	0.431450686460294	CD36/ACSL1	2
GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II	2/1068	17/18722	0.252665709639461	0.431450686460294	LILRB4/TGFB1	2
GO:1903541	regulation of exosomal secretion	2/1068	17/18722	0.252665709639461	0.431450686460294	SDCBP/RAB7A	2
GO:1904262	negative regulation of TORC1 signaling	2/1068	17/18722	0.252665709639461	0.431450686460294	SESN3/ATM	2
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	2/1068	17/18722	0.252665709639461	0.431450686460294	STAT1/PRKX	2
GO:0001838	embryonic epithelial tube formation	9/1068	121/18722	0.253555216711335	0.432103705404434	HIF1A/ST14/TGFB1/VASP/STK4/RALA/PRKACB/SKI/PFN1	9
GO:0042177	negative regulation of protein catabolic process	9/1068	121/18722	0.253555216711335	0.432103705404434	TIMP1/CST3/TIMP2/FLNA/CTSA/SDCBP/IRAK3/ROCK1/CAMLG	9
GO:0045931	positive regulation of mitotic cell cycle	9/1068	121/18722	0.253555216711335	0.432103705404434	AIF1/LGMN/RB1/EIF4EBP1/KMT2E/RGCC/DUSP3/ADAM17/RCC2	9
GO:0003009	skeletal muscle contraction	4/1068	45/18722	0.253848915146785	0.432103705404434	RCSD1/GSTO1/NR4A1/GAA	4
GO:0035272	exocrine system development	4/1068	45/18722	0.253848915146785	0.432103705404434	HGF/PLXND1/TGFB1/CDC42	4
GO:0035987	endodermal cell differentiation	4/1068	45/18722	0.253848915146785	0.432103705404434	ITGB2/ITGA4/MMP2/ITGA5	4
GO:0044088	regulation of vacuole organization	4/1068	45/18722	0.253848915146785	0.432103705404434	GRN/NUPR1/LRRK2/SCARB2	4
GO:0046189	phenol-containing compound biosynthetic process	4/1068	45/18722	0.253848915146785	0.432103705404434	ZEB2/NR4A2/MFSD12/APPL1	4
GO:0051985	negative regulation of chromosome segregation	4/1068	45/18722	0.253848915146785	0.432103705404434	DUSP1/ATM/APC/DYNC1LI1	4
GO:1905819	negative regulation of chromosome separation	4/1068	45/18722	0.253848915146785	0.432103705404434	DUSP1/ATM/APC/DYNC1LI1	4
GO:0008203	cholesterol metabolic process	10/1068	137/18722	0.255859819278385	0.435389336116735	APOE/NPC2/SOAT1/CYP27A1/OSBPL1A/ACAA2/APOBR/ABCG1/ABCA1/CEBPA	10
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	5/1068	60/18722	0.256582053856563	0.436205659297421	TAOK3/CDKN1A/ATM/FOXN3/TAOK1	5
GO:0030071	regulation of mitotic metaphase/anaphase transition	5/1068	60/18722	0.256582053856563	0.436205659297421	DUSP1/RB1/ATM/APC/DYNC1LI1	5
GO:0060038	cardiac muscle cell proliferation	5/1068	60/18722	0.256582053856563	0.436205659297421	MEF2C/TGFBR2/RUNX1/PRKAR1A/TGFBR1	5
GO:0071331	cellular response to hexose stimulus	11/1068	153/18722	0.257270458060735	0.437238233604953	HLA-DRB1/LGALS1/CYBA/TREM2/HIF1A/UCP2/RAC1/ABCG1/LRP1/STX4/KIF5B	11
GO:0048511	rhythmic process	20/1068	298/18722	0.257397908751261	0.437317101896034	ID2/JUN/ARRB2/RETN/ATF5/AXL/AHR/NCOR2/NR1H3/TRPM2/NAMPT/SGPL1/SETX/DDX5/BHLHE40/KLF10/GNAQ/UBE3A/EGR1/BHLHE41	20
GO:0001824	blastocyst development	8/1068	106/18722	0.258098513671532	0.43800407862157	SKIL/JUNB/LPAR6/CMTM3/KLF4/PTPN18/TGFBR1/RTN4	8
GO:0002062	chondrocyte differentiation	8/1068	106/18722	0.258098513671532	0.43800407862157	TGFBI/MEF2C/MAF/TGFB1/TGFBR2/TRPS1/RUNX1/TGFBR1	8
GO:0002323	natural killer cell activation involved in immune response	3/1068	31/18722	0.258938660267385	0.43800407862157	HLA-F/CORO1A/LAMP1	3
GO:0002717	positive regulation of natural killer cell mediated immunity	3/1068	31/18722	0.258938660267385	0.43800407862157	HLA-E/HLA-F/LAMP1	3
GO:0006613	cotranslational protein targeting to membrane	3/1068	31/18722	0.258938660267385	0.43800407862157	SSR3/SSR1/TRAM1	3
GO:0007190	activation of adenylate cyclase activity	3/1068	31/18722	0.258938660267385	0.43800407862157	ADORA3/CAP1/CALM3	3
GO:0008045	motor neuron axon guidance	3/1068	31/18722	0.258938660267385	0.43800407862157	ALCAM/RHOG/RAC1	3
GO:0032148	activation of protein kinase B activity	3/1068	31/18722	0.258938660267385	0.43800407862157	CCDC88A/IL18/OSBPL8	3
GO:0032509	endosome transport via multivesicular body sorting pathway	3/1068	31/18722	0.258938660267385	0.43800407862157	TMEM50A/CHMP3/CHMP1B	3
GO:0055022	negative regulation of cardiac muscle tissue growth	3/1068	31/18722	0.258938660267385	0.43800407862157	TGFBR2/PAK1/RGS2	3
GO:0055075	potassium ion homeostasis	3/1068	31/18722	0.258938660267385	0.43800407862157	ATP1B1/ATP1B3/ATP1A1	3
GO:0061117	negative regulation of heart growth	3/1068	31/18722	0.258938660267385	0.43800407862157	TGFBR2/PAK1/RGS2	3
GO:0097106	postsynaptic density organization	3/1068	31/18722	0.258938660267385	0.43800407862157	ABI3/LILRB2/ARF6	3
GO:1901797	negative regulation of signal transduction by p53 class mediator	3/1068	31/18722	0.258938660267385	0.43800407862157	CD74/CD44/ZNF385A	3
GO:0072329	monocarboxylic acid catabolic process	9/1068	122/18722	0.261114318718465	0.441545867691895	ACAA2/ABHD2/AKR1A1/ACAT1/CPT1A/FAH/PLA2G15/SCP2/HSD17B4	9
GO:0042147	retrograde transport, endosome to Golgi	7/1068	91/18722	0.262241578786502	0.443174306023165	STX10/LRRK2/STX6/GGA1/RAB29/DENND5A/RAB7A	7
GO:0051983	regulation of chromosome segregation	7/1068	91/18722	0.262241578786502	0.443174306023165	DUSP1/RB1/PLSCR1/ATM/APC/DYNC1LI1/RCC2	7
GO:0030856	regulation of epithelial cell differentiation	11/1068	154/18722	0.264007153780452	0.445878748606986	STAT1/ZFP36/ZFP36L1/VEGFA/SPRED1/PRKX/IL1B/BTG1/CEBPB/TNFRSF1A/ROCK1	11
GO:0071326	cellular response to monosaccharide stimulus	11/1068	154/18722	0.264007153780452	0.445878748606986	HLA-DRB1/LGALS1/CYBA/TREM2/HIF1A/UCP2/RAC1/ABCG1/LRP1/STX4/KIF5B	11
GO:0043487	regulation of RNA stability	12/1068	170/18722	0.264425790834215	0.446446047353387	VIM/ZFP36L2/ZFP36/SLC11A1/ZFP36L1/YBX1/TNFRSF1B/PABPC1/MYD88/BTG2/PABPC4/ROCK1	12
GO:0009123	nucleoside monophosphate metabolic process	6/1068	76/18722	0.265629204378689	0.448057263778496	TYMP/UPP1/DPYD/IMPDH1/HPRT1/TK2	6
GO:0045685	regulation of glial cell differentiation	6/1068	76/18722	0.265629204378689	0.448057263778496	TREM2/CXCR4/ID2/TLR2/TNFRSF1B/TGFB1	6
GO:0086001	cardiac muscle cell action potential	6/1068	76/18722	0.265629204378689	0.448057263778496	SLC8A1/FLNA/KCNE3/ATP1B1/CALM3/ATP1A1	6
GO:0010927	cellular component assembly involved in morphogenesis	8/1068	107/18722	0.266264993977721	0.448868576403245	CD9/MEF2A/TLR2/PMP22/PRKAR1A/FLII/AKAP13/PLEC	8
GO:0006195	purine nucleotide catabolic process	4/1068	46/18722	0.266609300847369	0.448868576403245	SAMHD1/NUDT3/HPRT1/ACAT1	4
GO:0006383	transcription by RNA polymerase III	4/1068	46/18722	0.266609300847369	0.448868576403245	POLR3GL/GTF3A/CEBPA/IVNS1ABP	4
GO:0007019	microtubule depolymerization	4/1068	46/18722	0.266609300847369	0.448868576403245	CIB1/ARHGEF2/APC/TAOK1	4
GO:0033047	regulation of mitotic sister chromatid segregation	4/1068	46/18722	0.266609300847369	0.448868576403245	DUSP1/ATM/APC/DYNC1LI1	4
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	4/1068	46/18722	0.266609300847369	0.448868576403245	AIF1/KMT2E/RGCC/ADAM17	4
GO:0030199	collagen fibril organization	5/1068	61/18722	0.267576647288011	0.450216273391365	RB1/COLGALT1/P4HA1/CRTAP/TGFBR1	5
GO:0071384	cellular response to corticosteroid stimulus	5/1068	61/18722	0.267576647288011	0.450216273391365	ZFP36L2/ZFP36/ZFP36L1/DDIT4/NR3C1	5
GO:0030216	keratinocyte differentiation	10/1068	139/18722	0.270154373815488	0.454270177970823	TXNIP/ASAH1/ZFP36/ZFP36L1/ST14/STK4/ADAM9/CSTA/ROCK1/PLEC	10
GO:0051783	regulation of nuclear division	10/1068	139/18722	0.270154373815488	0.454270177970823	DUSP1/RB1/IL1B/RGCC/ATM/PRKAR1A/APC/NUP62/DYNC1LI1/CDC42	10
GO:0070509	calcium ion import	7/1068	92/18722	0.271150815500982	0.45580367615056	CCL3/LGALS3/SLC8A1/PRNP/TRPM2/SLC30A1/MICU1	7
GO:0061448	connective tissue development	17/1068	252/18722	0.271921254466614	0.456956427624369	TIMP1/CD44/TGFBI/SORL1/SPI1/HIF1A/MEF2C/MAF/TGFB1/TGFBR2/CRIP1/TRPS1/RUNX1/IL6R/ACAT1/TGFBR1/EGR1	17
GO:0000209	protein polyubiquitination	16/1068	236/18722	0.273376158827071	0.457013715751513	IFI27/UBE2L6/TRIM22/DTX3L/TRIM14/GABARAP/TRIM38/RNF166/TNFAIP3/RNF135/UBE2W/UBE2D1/TTC3/UBE3A/XIAP/UBE2D3	16
GO:0006085	acetyl-CoA biosynthetic process	2/1068	18/18722	0.274289486785762	0.457013715751513	PDK4/ACAT1	2
GO:0009068	aspartate family amino acid catabolic process	2/1068	18/18722	0.274289486785762	0.457013715751513	SDS/SDSL	2
GO:0010985	negative regulation of lipoprotein particle clearance	2/1068	18/18722	0.274289486785762	0.457013715751513	APOC1/CSK	2
GO:0021534	cell proliferation in hindbrain	2/1068	18/18722	0.274289486785762	0.457013715751513	C5AR1/ATF5	2
GO:0030206	chondroitin sulfate biosynthetic process	2/1068	18/18722	0.274289486785762	0.457013715751513	DSE/CSGALNACT2	2
GO:0043116	negative regulation of vascular permeability	2/1068	18/18722	0.274289486785762	0.457013715751513	VEGFA/PTPRJ	2
GO:0043217	myelin maintenance	2/1068	18/18722	0.274289486785762	0.457013715751513	CXCR4/PLEC	2
GO:0044247	cellular polysaccharide catabolic process	2/1068	18/18722	0.274289486785762	0.457013715751513	AOAH/GAA	2
GO:0048268	clathrin coat assembly	2/1068	18/18722	0.274289486785762	0.457013715751513	FCHO2/PICALM	2
GO:0048643	positive regulation of skeletal muscle tissue development	2/1068	18/18722	0.274289486785762	0.457013715751513	MEF2C/FLOT1	2
GO:0060192	negative regulation of lipase activity	2/1068	18/18722	0.274289486785762	0.457013715751513	APOC1/RGS2	2
GO:0060716	labyrinthine layer blood vessel development	2/1068	18/18722	0.274289486785762	0.457013715751513	JUNB/VASH1	2
GO:0061484	hematopoietic stem cell homeostasis	2/1068	18/18722	0.274289486785762	0.457013715751513	TCIRG1/ADAR	2
GO:0061687	detoxification of inorganic compound	2/1068	18/18722	0.274289486785762	0.457013715751513	MT1X/SLC30A1	2
GO:0072234	metanephric nephron tubule development	2/1068	18/18722	0.274289486785762	0.457013715751513	STAT1/ACAT1	2
GO:0080182	histone H3-K4 trimethylation	2/1068	18/18722	0.274289486785762	0.457013715751513	KMT2E/ARID4A	2
GO:0099558	maintenance of synapse structure	2/1068	18/18722	0.274289486785762	0.457013715751513	CHCHD10/ARF6	2
GO:0110154	RNA decapping	2/1068	18/18722	0.274289486785762	0.457013715751513	ZFP36/NUDT3	2
GO:1900006	positive regulation of dendrite development	2/1068	18/18722	0.274289486785762	0.457013715751513	CYFIP1/IQGAP1	2
GO:1901673	regulation of mitotic spindle assembly	2/1068	18/18722	0.274289486785762	0.457013715751513	HSPA1A/CHMP1B	2
GO:1905820	positive regulation of chromosome separation	2/1068	18/18722	0.274289486785762	0.457013715751513	RB1/PLSCR1	2
GO:2000641	regulation of early endosome to late endosome transport	2/1068	18/18722	0.274289486785762	0.457013715751513	MSN/CHMP3	2
GO:0003180	aortic valve morphogenesis	3/1068	32/18722	0.274665581946286	0.457013715751513	RB1/TGFB1/ROCK1	3
GO:0008156	negative regulation of DNA replication	3/1068	32/18722	0.274665581946286	0.457013715751513	SLFN11/BCL6/S100A11	3
GO:0019835	cytolysis	3/1068	32/18722	0.274665581946286	0.457013715751513	LYZ/TGFB1/NINJ1	3
GO:0019934	cGMP-mediated signaling	3/1068	32/18722	0.274665581946286	0.457013715751513	APOE/CD36/PTK2B	3
GO:0045761	regulation of adenylate cyclase activity	3/1068	32/18722	0.274665581946286	0.457013715751513	TIMP2/GNAI2/CAP1	3
GO:0071875	adrenergic receptor signaling pathway	3/1068	32/18722	0.274665581946286	0.457013715751513	GNAI2/AKAP13/RGS2	3
GO:1901532	regulation of hematopoietic progenitor cell differentiation	3/1068	32/18722	0.274665581946286	0.457013715751513	SPI1/EIF2AK2/FNIP1	3
GO:2000191	regulation of fatty acid transport	3/1068	32/18722	0.274665581946286	0.457013715751513	SYK/ACSL1/IL1B	3
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	3/1068	32/18722	0.274665581946286	0.457013715751513	LGALS9/RUNX1/BCL6	3
GO:0055117	regulation of cardiac muscle contraction	6/1068	77/18722	0.27547817622902	0.458224487956779	SLC8A1/ATP1B1/CALM3/GSTO1/RGS2/ATP1A1	6
GO:0006575	cellular modified amino acid metabolic process	13/1068	188/18722	0.276765211559461	0.460223445785779	CTSB/GPX1/PLSCR1/OSBPL8/GPX4/MGST2/ABHD12/MTHFD2/CPT1A/GSTO1/SERINC1/PLA2G15/CLIC1	13
GO:0046165	alcohol biosynthetic process	10/1068	140/18722	0.277393173231312	0.460850960615111	APOE/ASAH1/PLEK/CYP27A1/ACAA2/PTAFR/SRD5A3/PTK2B/ABCG1/ACER3	10
GO:0050768	negative regulation of neurogenesis	10/1068	140/18722	0.277393173231312	0.460850960615111	SPP1/B2M/TREM2/TSPO/SORL1/YWHAH/ARHGAP4/IL1B/RTN4/SKI	10
GO:0001678	cellular glucose homeostasis	12/1068	172/18722	0.277398799124885	0.460850960615111	HLA-DRB1/LGALS1/CYBA/TREM2/HIF1A/UCP2/RAC1/ABCG1/LRP1/STX4/KIF5B/PIK3R1	12
GO:0035051	cardiocyte differentiation	11/1068	156/18722	0.277651055148449	0.461128068199763	HAMP/MEF2A/SLC8A1/MEF2C/ARRB2/VEGFA/TGFB1/PAK1/AKAP13/RGS2/PLEC	11
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	5/1068	62/18722	0.278672547798791	0.462255477381578	DUSP1/RB1/ATM/APC/DYNC1LI1	5
GO:0009311	oligosaccharide metabolic process	5/1068	62/18722	0.278672547798791	0.462255477381578	FBP1/GAL3ST4/ST8SIA4/GAA/GM2A	5
GO:0046148	pigment biosynthetic process	5/1068	62/18722	0.278672547798791	0.462255477381578	TSPO/ZEB2/MFSD12/HPRT1/APPL1	5
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	5/1068	62/18722	0.278672547798791	0.462255477381578	SDCBP/TGFB1/ENG/LRP1/TGFBR1	5
GO:0045332	phospholipid translocation	4/1068	47/18722	0.279482248089817	0.462745078457396	PLSCR1/P2RX7/ABCA1/TMEM30A	4
GO:0045747	positive regulation of Notch signaling pathway	4/1068	47/18722	0.279482248089817	0.462745078457396	BMP2K/ZMIZ1/STAT3/TSPAN14	4
GO:0050885	neuromuscular process controlling balance	4/1068	47/18722	0.279482248089817	0.462745078457396	TPP1/SLC1A3/GAA/GM2A	4
GO:0090279	regulation of calcium ion import	4/1068	47/18722	0.279482248089817	0.462745078457396	CCL3/LGALS3/PRNP/SLC30A1	4
GO:0101023	vascular endothelial cell proliferation	4/1068	47/18722	0.279482248089817	0.462745078457396	MEF2C/ITGA4/STAT3/ADAM17	4
GO:1905562	regulation of vascular endothelial cell proliferation	4/1068	47/18722	0.279482248089817	0.462745078457396	MEF2C/ITGA4/STAT3/ADAM17	4
GO:0034766	negative regulation of ion transmembrane transport	8/1068	109/18722	0.28281543914311	0.46812027902338	HAMP/KCNE3/SLC30A1/CALM3/CAB39/GSTO1/RGS2/PPIF	8
GO:0010469	regulation of signaling receptor activity	12/1068	173/18722	0.283959745403566	0.469870219625159	IFNGR2/LILRB4/HIF1A/MEF2C/HBEGF/PLAU/NCF1/JAK2/PTK2B/DAPK1/ADAM17/KLHL24	12
GO:0006066	alcohol metabolic process	23/1068	353/18722	0.284187090975932	0.470102251044184	APOE/NPC2/ASAH1/PLEK/ALDH2/ALDH1A1/SOAT1/NUDT3/CYP27A1/OSBPL1A/ACAA2/PTAFR/APOBR/SRD5A3/RDH11/PTK2B/AKR1A1/ABCG1/DHRS3/ABCA1/DHRS4/CEBPA/ACER3	23
GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	6/1068	78/18722	0.285411159712391	0.471548872568298	PSAP/RGS1/GNAI2/FLNA/MARCO/RGS2	6
GO:0061045	negative regulation of wound healing	6/1068	78/18722	0.285411159712391	0.471548872568298	APOE/CD9/ALOX5/PLAU/SH2B3/SERPING1	6
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	6/1068	78/18722	0.285411159712391	0.471548872568298	HMOX1/RHOA/CIB1/KLF4/VEGFA/SPRED1	6
GO:1901616	organic hydroxy compound catabolic process	6/1068	78/18722	0.285411159712391	0.471548872568298	APOE/ALDH2/NUDT3/CYP27A1/SRD5A3/FAH	6
GO:0008016	regulation of heart contraction	14/1068	206/18722	0.287875403743995	0.475474649097826	MEF2A/SLC8A1/FLNA/CELF2/HBEGF/ADORA3/KCNE3/JAK2/ATP1B1/CALM3/GSTO1/GAA/RGS2/ATP1A1	14
GO:0002042	cell migration involved in sprouting angiogenesis	7/1068	94/18722	0.289199510856659	0.475707862715551	HMOX1/RHOA/CIB1/KLF4/VEGFA/SPRED1/NR4A1	7
GO:0010389	regulation of G2/M transition of mitotic cell cycle	7/1068	94/18722	0.289199510856659	0.475707862715551	TAOK3/CDKN1A/RNASEH2B/ATM/FOXN3/TAOK1/RCC2	7
GO:1903035	negative regulation of response to wounding	7/1068	94/18722	0.289199510856659	0.475707862715551	APOE/SPP1/CD9/ALOX5/PLAU/SH2B3/SERPING1	7
GO:0009755	hormone-mediated signaling pathway	13/1068	190/18722	0.289332330511863	0.475707862715551	YWHAH/RHOA/ZMIZ1/JAK2/NCOR2/ABHD2/ACSL1/PRCP/DDX5/PAK1/UBE3A/NR3C1/APPL1	13
GO:0001947	heart looping	5/1068	63/18722	0.289857992230793	0.475707862715551	HIF1A/MEF2C/ENG/TGFBR2/NOTCH2	5
GO:0030239	myofibril assembly	5/1068	63/18722	0.289857992230793	0.475707862715551	MEF2A/PRKAR1A/FLII/AKAP13/PLEC	5
GO:0099601	regulation of neurotransmitter receptor activity	5/1068	63/18722	0.289857992230793	0.475707862715551	IFNGR2/MEF2C/PTK2B/DAPK1/KLHL24	5
GO:1902099	regulation of metaphase/anaphase transition of cell cycle	5/1068	63/18722	0.289857992230793	0.475707862715551	DUSP1/RB1/ATM/APC/DYNC1LI1	5
GO:1902373	negative regulation of mRNA catabolic process	5/1068	63/18722	0.289857992230793	0.475707862715551	ZFP36/SLC11A1/YBX1/PABPC1/MYD88	5
GO:2000242	negative regulation of reproductive process	5/1068	63/18722	0.289857992230793	0.475707862715551	TIMP1/DUSP1/ARHGDIB/PRKAR1A/PRKACB	5
GO:0001881	receptor recycling	3/1068	33/18722	0.290485064426935	0.475707862715551	SORL1/ARAP1/RAB29	3
GO:0009156	ribonucleoside monophosphate biosynthetic process	3/1068	33/18722	0.290485064426935	0.475707862715551	UPP1/IMPDH1/HPRT1	3
GO:0010984	regulation of lipoprotein particle clearance	3/1068	33/18722	0.290485064426935	0.475707862715551	APOC1/TREM2/CSK	3
GO:0019362	pyridine nucleotide metabolic process	3/1068	33/18722	0.290485064426935	0.475707862715551	PARP9/KYNU/NAMPT	3
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	3/1068	33/18722	0.290485064426935	0.475707862715551	HIF1A/ITGA5/IL1B	3
GO:0031116	positive regulation of microtubule polymerization	3/1068	33/18722	0.290485064426935	0.475707862715551	HSPA1A/RAC1/PAK1	3
GO:0033198	response to ATP	3/1068	33/18722	0.290485064426935	0.475707862715551	SLC8A1/CASP1/P2RX7	3
GO:0046320	regulation of fatty acid oxidation	3/1068	33/18722	0.290485064426935	0.475707862715551	PDK4/PRKAG2/CPT1A	3
GO:0046496	nicotinamide nucleotide metabolic process	3/1068	33/18722	0.290485064426935	0.475707862715551	PARP9/KYNU/NAMPT	3
GO:0061842	microtubule organizing center localization	3/1068	33/18722	0.290485064426935	0.475707862715551	ARPC5/RANBP2/KIF5B	3
GO:0099084	postsynaptic specialization organization	3/1068	33/18722	0.290485064426935	0.475707862715551	ABI3/LILRB2/ARF6	3
GO:0120033	negative regulation of plasma membrane bounded cell projection assembly	3/1068	33/18722	0.290485064426935	0.475707862715551	ABI3/ARHGAP24/CAPZB	3
GO:1900181	negative regulation of protein localization to nucleus	3/1068	33/18722	0.290485064426935	0.475707862715551	LILRB4/CD36/MDFIC	3
GO:1901099	negative regulation of signal transduction in absence of ligand	3/1068	33/18722	0.290485064426935	0.475707862715551	HSPA1A/MCL1/IL1B	3
GO:1901976	regulation of cell cycle checkpoint	3/1068	33/18722	0.290485064426935	0.475707862715551	DUSP1/RNASEH2B/DYNC1LI1	3
GO:1902692	regulation of neuroblast proliferation	3/1068	33/18722	0.290485064426935	0.475707862715551	HIF1A/VEGFA/LRRK2	3
GO:1904031	positive regulation of cyclin-dependent protein kinase activity	3/1068	33/18722	0.290485064426935	0.475707862715551	CDKN1A/RGCC/ADAM17	3
GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	3/1068	33/18722	0.290485064426935	0.475707862715551	HSPA1A/MCL1/IL1B	3
GO:0043488	regulation of mRNA stability	11/1068	158/18722	0.291504844515544	0.477233052489647	VIM/ZFP36L2/ZFP36/SLC11A1/ZFP36L1/YBX1/PABPC1/MYD88/BTG2/PABPC4/ROCK1	11
GO:0042149	cellular response to glucose starvation	4/1068	48/18722	0.292449459082488	0.478199176123972	IFI16/UPP1/PRKAG2/SESN3	4
GO:0045005	DNA-dependent DNA replication maintenance of fidelity	4/1068	48/18722	0.292449459082488	0.478199176123972	SAMHD1/SLFN11/FAM111A/BOD1L1	4
GO:0045839	negative regulation of mitotic nuclear division	4/1068	48/18722	0.292449459082488	0.478199176123972	DUSP1/ATM/APC/DYNC1LI1	4
GO:0097720	calcineurin-mediated signaling	4/1068	48/18722	0.292449459082488	0.478199176123972	CLEC7A/HOMER3/CIB1/PRNP	4
GO:1903522	regulation of blood circulation	17/1068	256/18722	0.293525198939987	0.479162774004517	MEF2A/SLC8A1/DOCK4/FLNA/RHOA/CELF2/HBEGF/TBXAS1/ADORA3/KCNE3/JAK2/ATP1B1/CALM3/GSTO1/GAA/RGS2/ATP1A1	17
GO:0001696	gastric acid secretion	2/1068	19/18722	0.295880348959053	0.479162774004517	SGK1/SNX10	2
GO:0003085	negative regulation of systemic arterial blood pressure	2/1068	19/18722	0.295880348959053	0.479162774004517	SOD2/PRCP	2
GO:0006044	N-acetylglucosamine metabolic process	2/1068	19/18722	0.295880348959053	0.479162774004517	GNPDA1/NAGK	2
GO:0006144	purine nucleobase metabolic process	2/1068	19/18722	0.295880348959053	0.479162774004517	DPYD/HPRT1	2
GO:0006309	apoptotic DNA fragmentation	2/1068	19/18722	0.295880348959053	0.479162774004517	DNASE2/BAX	2
GO:0006670	sphingosine metabolic process	2/1068	19/18722	0.295880348959053	0.479162774004517	ASAH1/ACER3	2
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	2/1068	19/18722	0.295880348959053	0.479162774004517	IMPDH1/HPRT1	2
GO:0010738	regulation of protein kinase A signaling	2/1068	19/18722	0.295880348959053	0.479162774004517	LRRK2/PJA2	2
GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling	2/1068	19/18722	0.295880348959053	0.479162774004517	TREM2/KLF4	2
GO:0015802	basic amino acid transport	2/1068	19/18722	0.295880348959053	0.479162774004517	SLC11A1/SLC7A7	2
GO:0030011	maintenance of cell polarity	2/1068	19/18722	0.295880348959053	0.479162774004517	NCKAP1L/ARPC5	2
GO:0031290	retinal ganglion cell axon guidance	2/1068	19/18722	0.295880348959053	0.479162774004517	ALCAM/VEGFA	2
GO:0032011	ARF protein signal transduction	2/1068	19/18722	0.295880348959053	0.479162774004517	CYTH1/CYTH4	2
GO:0032012	regulation of ARF protein signal transduction	2/1068	19/18722	0.295880348959053	0.479162774004517	CYTH1/CYTH4	2
GO:0032026	response to magnesium ion	2/1068	19/18722	0.295880348959053	0.479162774004517	FBP1/CD14	2
GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	2/1068	19/18722	0.295880348959053	0.479162774004517	ACSL1/ACSL4	2
GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate	2/1068	19/18722	0.295880348959053	0.479162774004517	APOBEC3C/APOBEC3A	2
GO:0045821	positive regulation of glycolytic process	2/1068	19/18722	0.295880348959053	0.479162774004517	HIF1A/P2RX7	2
GO:0046716	muscle cell cellular homeostasis	2/1068	19/18722	0.295880348959053	0.479162774004517	HIF1A/GAA	2
GO:0048490	anterograde synaptic vesicle transport	2/1068	19/18722	0.295880348959053	0.479162774004517	BLOC1S1/BLOC1S2	2
GO:0050961	detection of temperature stimulus involved in sensory perception	2/1068	19/18722	0.295880348959053	0.479162774004517	CXCR4/ARRB2	2
GO:0061760	antifungal innate immune response	2/1068	19/18722	0.295880348959053	0.479162774004517	SPI1/CLEC7A	2
GO:0062099	negative regulation of programmed necrotic cell death	2/1068	19/18722	0.295880348959053	0.479162774004517	NUPR1/ARHGEF2	2
GO:0070233	negative regulation of T cell apoptotic process	2/1068	19/18722	0.295880348959053	0.479162774004517	HIF1A/TSC22D3	2
GO:0070262	peptidyl-serine dephosphorylation	2/1068	19/18722	0.295880348959053	0.479162774004517	DUSP1/PPP1R15A	2
GO:0097501	stress response to metal ion	2/1068	19/18722	0.295880348959053	0.479162774004517	MT1X/SLC30A1	2
GO:0099514	synaptic vesicle cytoskeletal transport	2/1068	19/18722	0.295880348959053	0.479162774004517	BLOC1S1/BLOC1S2	2
GO:0099517	synaptic vesicle transport along microtubule	2/1068	19/18722	0.295880348959053	0.479162774004517	BLOC1S1/BLOC1S2	2
GO:1901659	glycosyl compound biosynthetic process	2/1068	19/18722	0.295880348959053	0.479162774004517	HPRT1/TK2	2
GO:2000269	regulation of fibroblast apoptotic process	2/1068	19/18722	0.295880348959053	0.479162774004517	BID/BTG1	2
GO:2000369	regulation of clathrin-dependent endocytosis	2/1068	19/18722	0.295880348959053	0.479162774004517	BMP2K/SMAP1	2
GO:0046942	carboxylic acid transport	18/1068	273/18722	0.296543068654964	0.480091928731528	PSAP/SLC11A1/SLC7A7/CD36/SLCO2B1/SLC16A3/SYK/SLC38A6/AQP9/ABCC3/LRRC8C/MPC1/SLC6A6/SFXN3/MFSD12/IL1B/SLC1A3/RGS2	18
GO:0022900	electron transport chain	12/1068	175/18722	0.297219204285828	0.481042239450008	CYBA/ALDH2/CYBB/NCF2/ME2/NCF1/BID/NQO2/SCO2/AKR1A1/DHRS3/PLEC	12
GO:0009314	response to radiation	29/1068	456/18722	0.298178875234914	0.482450737861349	GPX1/CYBA/TIMP1/HAMP/SOD2/FOS/DUSP1/IFI16/ID2/GRB2/JUN/HIF1A/PTPRC/CARD16/CRIP1/PLK3/NAMPT/MMP2/CDKN1A/ERCC1/ATM/BHLHE40/SLC1A3/RHOB/GNAQ/BAX/PIAS1/EGR1/PIK3R1	29
GO:0006942	regulation of striated muscle contraction	7/1068	95/18722	0.298326700863615	0.482545227176279	SLC8A1/ATP1B1/CALM3/GSTO1/NR4A1/RGS2/ATP1A1	7
GO:0015718	monocarboxylic acid transport	8/1068	111/18722	0.299624127041237	0.484498588407107	CD36/SLCO2B1/SLC16A3/SYK/AQP9/ABCC3/MPC1/IL1B	8
GO:0006749	glutathione metabolic process	5/1068	64/18722	0.301121336819542	0.486191123123354	GPX1/GPX4/MGST2/GSTO1/CLIC1	5
GO:0046579	positive regulation of Ras protein signal transduction	5/1068	64/18722	0.301121336819542	0.486191123123354	GPR65/LPAR6/NOTCH2/RAC1/AKAP13	5
GO:0046854	phosphatidylinositol phosphate biosynthetic process	5/1068	64/18722	0.301121336819542	0.486191123123354	SOCS3/EFR3A/ATM/PIK3R1/SOCS6	5
GO:0055002	striated muscle cell development	5/1068	64/18722	0.301121336819542	0.486191123123354	MEF2A/PRKAR1A/FLII/AKAP13/PLEC	5
GO:0098930	axonal transport	5/1068	64/18722	0.301121336819542	0.486191123123354	HIF1A/BLOC1S1/BLOC1S2/ARL8B/KIF5B	5
GO:0045165	cell fate commitment	17/1068	258/18722	0.30452698293483	0.491542805837972	ID2/MEF2C/RHOA/KLF4/PRDM1/NOTCH2/MITF/IL6R/SPN/ARHGEF2/STAT6/MCL1/STAT3/TGFBR1/APC/CDC42/RAB10	17
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	4/1068	49/18722	0.305493053989114	0.492448120984082	SDCBP/TGFB1/ENG/TGFBR1	4
GO:0046605	regulation of centrosome cycle	4/1068	49/18722	0.305493053989114	0.492448120984082	ATF5/NUP62/CHMP3/CHMP1B	4
GO:0050832	defense response to fungus	4/1068	49/18722	0.305493053989114	0.492448120984082	HAMP/COTL1/SPI1/CLEC7A	4
GO:1990573	potassium ion import across plasma membrane	4/1068	49/18722	0.305493053989114	0.492448120984082	ATP1B1/WNK1/ATP1B3/ATP1A1	4
GO:0000038	very long-chain fatty acid metabolic process	3/1068	34/18722	0.306365519300142	0.492448120984082	ACSL1/HACD4/HSD17B4	3
GO:0009112	nucleobase metabolic process	3/1068	34/18722	0.306365519300142	0.492448120984082	TYMP/DPYD/HPRT1	3
GO:0009649	entrainment of circadian clock	3/1068	34/18722	0.306365519300142	0.492448120984082	ID2/BHLHE40/GNAQ	3
GO:0016242	negative regulation of macroautophagy	3/1068	34/18722	0.306365519300142	0.492448120984082	NUPR1/HMOX1/LRRK2	3
GO:0019076	viral release from host cell	3/1068	34/18722	0.306365519300142	0.492448120984082	ARL8B/CHMP3/RAB7A	3
GO:0035890	exit from host	3/1068	34/18722	0.306365519300142	0.492448120984082	ARL8B/CHMP3/RAB7A	3
GO:0035891	exit from host cell	3/1068	34/18722	0.306365519300142	0.492448120984082	ARL8B/CHMP3/RAB7A	3
GO:0043276	anoikis	3/1068	34/18722	0.306365519300142	0.492448120984082	PDK4/ITGA5/MCL1	3
GO:0048741	skeletal muscle fiber development	3/1068	34/18722	0.306365519300142	0.492448120984082	GPX1/SKI/PLEC	3
GO:1904893	negative regulation of receptor signaling pathway via STAT	3/1068	34/18722	0.306365519300142	0.492448120984082	SH2B3/PARP14/SOCS3	3
GO:0031644	regulation of nervous system process	10/1068	144/18722	0.306885193073977	0.493136540151036	FABP5/TYMP/CCL3/CTSC/HGF/ITGAX/TNFRSF1B/PTAFR/LRRK2/PTK2B	10
GO:0003073	regulation of systemic arterial blood pressure	7/1068	96/18722	0.307514270718362	0.494000299135541	CYBA/CTSZ/SOD2/RHOA/ATP6AP2/PRCP/WNK1	7
GO:0033865	nucleoside bisphosphate metabolic process	9/1068	128/18722	0.307803389441904	0.494023524517701	PPT1/PDK4/KYNU/ACOT9/ACSL1/PAPSS1/ACAT1/ACSL4/HSD17B4	9
GO:0033875	ribonucleoside bisphosphate metabolic process	9/1068	128/18722	0.307803389441904	0.494023524517701	PPT1/PDK4/KYNU/ACOT9/ACSL1/PAPSS1/ACAT1/ACSL4/HSD17B4	9
GO:0034032	purine nucleoside bisphosphate metabolic process	9/1068	128/18722	0.307803389441904	0.494023524517701	PPT1/PDK4/KYNU/ACOT9/ACSL1/PAPSS1/ACAT1/ACSL4/HSD17B4	9
GO:0150063	visual system development	24/1068	375/18722	0.308991419309054	0.495782842281194	VIM/C3/C1QA/SKIL/HIF1A/KLF4/VEGFA/MAF/TGFBR2/TCIRG1/PRDM1/ITGAM/PBX3/NOTCH2/MITF/SPRED1/SCO2/STAT3/TGFBR1/GNB1/MAX/SKI/PFDN5/BAX	24
GO:0051648	vesicle localization	12/1068	177/18722	0.310646748528527	0.498290682241359	MYO5A/TCIRG1/MYO1F/TANC2/ITGA4/MYO1G/LRRK2/BLOC1S1/BLOC1S2/TMED10/PICALM/KIF5B	12
GO:0010965	regulation of mitotic sister chromatid separation	5/1068	65/18722	0.312451085519384	0.500292598653589	DUSP1/RB1/ATM/APC/DYNC1LI1	5
GO:0038034	signal transduction in absence of ligand	5/1068	65/18722	0.312451085519384	0.500292598653589	BCL2A1/HSPA1A/MCL1/IL1B/BAX	5
GO:0043489	RNA stabilization	5/1068	65/18722	0.312451085519384	0.500292598653589	ZFP36/SLC11A1/YBX1/PABPC1/MYD88	5
GO:0044784	metaphase/anaphase transition of cell cycle	5/1068	65/18722	0.312451085519384	0.500292598653589	DUSP1/RB1/ATM/APC/DYNC1LI1	5
GO:0090307	mitotic spindle assembly	5/1068	65/18722	0.312451085519384	0.500292598653589	FLNA/RHOA/HSPA1A/KPNB1/CHMP1B	5
GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	5/1068	65/18722	0.312451085519384	0.500292598653589	BCL2A1/HSPA1A/MCL1/IL1B/BAX	5
GO:0003205	cardiac chamber development	11/1068	161/18722	0.312632357756532	0.500434352552432	HIF1A/MEF2C/PLXND1/TGFB1/ENG/TGFBR2/PRDM1/NOTCH2/CNTRL/DHRS3/TGFBR1	11
GO:0007269	neurotransmitter secretion	10/1068	145/18722	0.314376454639199	0.502927764373886	PPT1/MEF2C/RAP1A/MCTP1/LRRK2/SLC30A1/STXBP2/STX4/CALM3/NR4A1	10
GO:0099643	signal release from synapse	10/1068	145/18722	0.314376454639199	0.502927764373886	PPT1/MEF2C/RAP1A/MCTP1/LRRK2/SLC30A1/STXBP2/STX4/CALM3/NR4A1	10
GO:0001523	retinoid metabolic process	6/1068	81/18722	0.315632110200038	0.503687619963427	ALDH1A1/SCPEP1/RDH11/LRP1/DHRS3/DHRS4	6
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	6/1068	81/18722	0.315632110200038	0.503687619963427	SKIL/HSPA1A/SPRED1/HTRA1/ADAM17/SKI	6
GO:0007498	mesoderm development	9/1068	129/18722	0.315771485208267	0.503687619963427	ZFP36L1/KLF4/VEGFA/HCK/BTK/JAK2/IKZF1/SECTM1/PRKAR1A	9
GO:0000272	polysaccharide catabolic process	2/1068	20/18722	0.31737173978422	0.503687619963427	AOAH/GAA	2
GO:0006700	C21-steroid hormone biosynthetic process	2/1068	20/18722	0.31737173978422	0.503687619963427	TSPO/EGR1	2
GO:0006837	serotonin transport	2/1068	20/18722	0.31737173978422	0.503687619963427	SYK/LILRB1	2
GO:0006896	Golgi to vacuole transport	2/1068	20/18722	0.31737173978422	0.503687619963427	LAPTM5/LAMP1	2
GO:0017121	plasma membrane phospholipid scrambling	2/1068	20/18722	0.31737173978422	0.503687619963427	PLSCR1/P2RX7	2
GO:0032793	positive regulation of CREB transcription factor activity	2/1068	20/18722	0.31737173978422	0.503687619963427	VEGFA/CAMK1D	2
GO:0033005	positive regulation of mast cell activation	2/1068	20/18722	0.31737173978422	0.503687619963427	SYK/FGR	2
GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate	2/1068	20/18722	0.31737173978422	0.503687619963427	APOBEC3C/APOBEC3A	2
GO:0042359	vitamin D metabolic process	2/1068	20/18722	0.31737173978422	0.503687619963427	LGMN/CYP27A1	2
GO:0045063	T-helper 1 cell differentiation	2/1068	20/18722	0.31737173978422	0.503687619963427	SPN/STAT6	2
GO:0045844	positive regulation of striated muscle tissue development	2/1068	20/18722	0.31737173978422	0.503687619963427	MEF2C/FLOT1	2
GO:0048636	positive regulation of muscle organ development	2/1068	20/18722	0.31737173978422	0.503687619963427	MEF2C/FLOT1	2
GO:0048670	regulation of collateral sprouting	2/1068	20/18722	0.31737173978422	0.503687619963427	SPP1/LRP1	2
GO:0051004	regulation of lipoprotein lipase activity	2/1068	20/18722	0.31737173978422	0.503687619963427	APOC1/NR1H3	2
GO:0061003	positive regulation of dendritic spine morphogenesis	2/1068	20/18722	0.31737173978422	0.503687619963427	ACTR2/DBNL	2
GO:0061318	renal filtration cell differentiation	2/1068	20/18722	0.31737173978422	0.503687619963427	NOTCH2/IQGAP1	2
GO:0070166	enamel mineralization	2/1068	20/18722	0.31737173978422	0.503687619963427	TCIRG1/FAM20C	2
GO:0071379	cellular response to prostaglandin stimulus	2/1068	20/18722	0.31737173978422	0.503687619963427	PTGER4/GNB1	2
GO:0072112	glomerular visceral epithelial cell differentiation	2/1068	20/18722	0.31737173978422	0.503687619963427	NOTCH2/IQGAP1	2
GO:1903206	negative regulation of hydrogen peroxide-induced cell death	2/1068	20/18722	0.31737173978422	0.503687619963427	HGF/LRRK2	2
GO:1904263	positive regulation of TORC1 signaling	2/1068	20/18722	0.31737173978422	0.503687619963427	RRAGD/GPR137B	2
GO:1990182	exosomal secretion	2/1068	20/18722	0.31737173978422	0.503687619963427	SDCBP/RAB7A	2
GO:2000010	positive regulation of protein localization to cell surface	2/1068	20/18722	0.31737173978422	0.503687619963427	TYROBP/STX4	2
GO:2000479	regulation of cAMP-dependent protein kinase activity	2/1068	20/18722	0.31737173978422	0.503687619963427	PRKAG2/PRKAR1A	2
GO:0006220	pyrimidine nucleotide metabolic process	4/1068	50/18722	0.318595613686827	0.50429508109537	TYMP/UPP1/DPYD/MBD4	4
GO:0008089	anterograde axonal transport	4/1068	50/18722	0.318595613686827	0.50429508109537	BLOC1S1/BLOC1S2/ARL8B/KIF5B	4
GO:0038202	TORC1 signaling	4/1068	50/18722	0.318595613686827	0.50429508109537	RRAGD/GPR137B/SESN3/ATM	4
GO:0042572	retinol metabolic process	4/1068	50/18722	0.318595613686827	0.50429508109537	ALDH1A1/RDH11/DHRS3/DHRS4	4
GO:0060425	lung morphogenesis	4/1068	50/18722	0.318595613686827	0.50429508109537	CTSZ/CTSH/TGFBR2/CDC42	4
GO:0060688	regulation of morphogenesis of a branching structure	4/1068	50/18722	0.318595613686827	0.50429508109537	HGF/VEGFA/LRRK2/RTN4	4
GO:0071709	membrane assembly	4/1068	50/18722	0.318595613686827	0.50429508109537	STX4/PICALM/FLOT1/S100A10	4
GO:1901570	fatty acid derivative biosynthetic process	4/1068	50/18722	0.318595613686827	0.50429508109537	PPT1/ALOX5/ACSL1/ACSL4	4
GO:2000677	regulation of transcription regulatory region DNA binding	4/1068	50/18722	0.318595613686827	0.50429508109537	TMSB4X/RB1/KLF4/TGFB1	4
GO:0030705	cytoskeleton-dependent intracellular transport	13/1068	195/18722	0.321448630046788	0.508184206651589	CCDC88A/HIF1A/TUBA1A/MYO5A/MYO1F/TANC2/MYO1G/BLOC1S1/BLOC1S2/ARL8B/LAMP1/CDC42/KIF5B	13
GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	10/1068	146/18722	0.321908584283763	0.508184206651589	GPR65/GNAI2/PTGER4/ADGRE2/GNA13/ADCY7/ABCA1/GNB1/GNAQ/AKAP13	10
GO:0010675	regulation of cellular carbohydrate metabolic process	10/1068	146/18722	0.321908584283763	0.508184206651589	NUPR1/PLEK/FBP1/PDK4/DDIT4/PTAFR/SCARB2/PTK2B/STAT3/RANBP2	10
GO:0006084	acetyl-CoA metabolic process	3/1068	35/18722	0.322276937576304	0.508184206651589	PDK4/KYNU/ACAT1	3
GO:0006739	NADP metabolic process	3/1068	35/18722	0.322276937576304	0.508184206651589	ME2/KCNAB2/PGLS	3
GO:0010837	regulation of keratinocyte proliferation	3/1068	35/18722	0.322276937576304	0.508184206651589	ZFP36/ZFP36L1/NOTCH2	3
GO:0019068	virion assembly	3/1068	35/18722	0.322276937576304	0.508184206651589	APOE/CHMP3/CHMP1B	3
GO:0032350	regulation of hormone metabolic process	3/1068	35/18722	0.322276937576304	0.508184206651589	HIF1A/EGR1/ATP1A1	3
GO:0034331	cell junction maintenance	3/1068	35/18722	0.322276937576304	0.508184206651589	CSF1R/CHCHD10/ARF6	3
GO:0060236	regulation of mitotic spindle organization	3/1068	35/18722	0.322276937576304	0.508184206651589	HSPA1A/NUP62/CHMP1B	3
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	3/1068	35/18722	0.322276937576304	0.508184206651589	HMOX1/CIB1/VEGFA	3
GO:1905207	regulation of cardiocyte differentiation	3/1068	35/18722	0.322276937576304	0.508184206651589	MEF2C/ARRB2/TGFB1	3
GO:1905898	positive regulation of response to endoplasmic reticulum stress	3/1068	35/18722	0.322276937576304	0.508184206651589	HERPUD1/BAX/PIK3R1	3
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	5/1068	66/18722	0.323835916168476	0.510344218354291	PTPRC/TGFB1/BCL6/STAT6/ERCC1	5
GO:0016444	somatic cell DNA recombination	5/1068	66/18722	0.323835916168476	0.510344218354291	PTPRC/TGFB1/BCL6/STAT6/ERCC1	5
GO:0006457	protein folding	14/1068	212/18722	0.324875753201651	0.511833449423682	CD74/B2M/GRN/HSPA1A/FKBP5/CRTAP/ERO1A/HSPH1/CANX/DNAJC3/PFDN5/RANBP2/PPIF/SDF2L1	14
GO:0046364	monosaccharide biosynthetic process	6/1068	82/18722	0.325819320233312	0.513170184465544	SDS/FBP1/AKR1A1/PGK1/ATF3/RANBP2	6
GO:0061337	cardiac conduction	7/1068	98/18722	0.326046093575429	0.513377508296765	MEF2A/SLC8A1/FLNA/KCNE3/ATP1B1/CALM3/ATP1A1	7
GO:0006006	glucose metabolic process	13/1068	196/18722	0.327975454827509	0.516264747447268	FABP5/SDS/FBP1/PDK4/OAS1/ADPGK/AKR1A1/SERP1/CPT1A/PGK1/GAA/ATF3/RANBP2	13
GO:1902652	secondary alcohol metabolic process	10/1068	147/18722	0.329478349241675	0.518479198748346	APOE/NPC2/SOAT1/CYP27A1/OSBPL1A/ACAA2/APOBR/ABCG1/ABCA1/CEBPA	10
GO:0071897	DNA biosynthetic process	12/1068	180/18722	0.331062412842385	0.520813901082763	DUSP1/ARRB2/HGF/KLF4/POLD4/PARP4/PTK2B/CDKN1A/RGCC/ATM/TK2/NOP10	12
GO:0001505	regulation of neurotransmitter levels	14/1068	213/18722	0.331155021240727	0.520813901082763	GCHFR/PPT1/MEF2C/HNMT/RAP1A/MCTP1/LRRK2/SLC30A1/STXBP2/STX4/CALM3/SLC1A3/NR4A1/FLOT1	14
GO:0021872	forebrain generation of neurons	4/1068	51/18722	0.33174021700442	0.521430297394655	B2M/RHOA/ZMIZ1/ZSWIM6	4
GO:0060043	regulation of cardiac muscle cell proliferation	4/1068	51/18722	0.33174021700442	0.521430297394655	MEF2C/TGFBR2/RUNX1/TGFBR1	4
GO:0000077	DNA damage checkpoint signaling	8/1068	115/18722	0.333862871957143	0.52461387800837	TAOK3/PLK3/CDKN1A/RNASEH2B/RPS27L/ATM/FOXN3/TAOK1	8
GO:0050680	negative regulation of epithelial cell proliferation	11/1068	164/18722	0.33411093826031	0.5248508363472	APOE/B2M/NUPR1/STAT1/MEF2C/RB1/ALOX5/TGFB1/VASH1/RGCC/TGFBR1	11
GO:0048814	regulation of dendrite morphogenesis	5/1068	67/18722	0.335264704528724	0.52620370728243	YWHAH/ACTR2/SDC2/RAP2A/DBNL	5
GO:0051306	mitotic sister chromatid separation	5/1068	67/18722	0.335264704528724	0.52620370728243	DUSP1/RB1/ATM/APC/DYNC1LI1	5
GO:0061371	determination of heart left/right asymmetry	5/1068	67/18722	0.335264704528724	0.52620370728243	HIF1A/MEF2C/ENG/TGFBR2/NOTCH2	5
GO:0060291	long-term synaptic potentiation	7/1068	99/18722	0.335378194112191	0.526228768662223	APOE/TYROBP/LGMN/PRNP/LILRB2/PTK2B/STX4	7
GO:0048880	sensory system development	24/1068	381/18722	0.337014956547267	0.526852420423581	VIM/C3/C1QA/SKIL/HIF1A/KLF4/VEGFA/MAF/TGFBR2/TCIRG1/PRDM1/ITGAM/PBX3/NOTCH2/MITF/SPRED1/SCO2/STAT3/TGFBR1/GNB1/MAX/SKI/PFDN5/BAX	24
GO:0099504	synaptic vesicle cycle	12/1068	181/18722	0.337931375747174	0.526852420423581	ACTB/RAP1A/LRRK2/ITSN2/CYFIP1/STX4/CALM3/ROCK1/CANX/FCHO2/PICALM/ARF6	12
GO:0003203	endocardial cushion morphogenesis	3/1068	36/18722	0.338190910262206	0.526852420423581	ENG/TGFBR2/TGFBR1	3
GO:0006699	bile acid biosynthetic process	3/1068	36/18722	0.338190910262206	0.526852420423581	CYP27A1/OSBPL1A/SCP2	3
GO:0017004	cytochrome complex assembly	3/1068	36/18722	0.338190910262206	0.526852420423581	CYBA/SCO2/OXA1L	3
GO:0045746	negative regulation of Notch signaling pathway	3/1068	36/18722	0.338190910262206	0.526852420423581	BCL6/LFNG/NFKBIA	3
GO:1903539	protein localization to postsynaptic membrane	3/1068	36/18722	0.338190910262206	0.526852420423581	RAP1A/ADAM10/RAB8A	3
GO:0000002	mitochondrial genome maintenance	2/1068	21/18722	0.338704789927614	0.526852420423581	TYMP/MEF2A	2
GO:0002689	negative regulation of leukocyte chemotaxis	2/1068	21/18722	0.338704789927614	0.526852420423581	DUSP1/RIN3	2
GO:0009127	purine nucleoside monophosphate biosynthetic process	2/1068	21/18722	0.338704789927614	0.526852420423581	IMPDH1/HPRT1	2
GO:0010988	regulation of low-density lipoprotein particle clearance	2/1068	21/18722	0.338704789927614	0.526852420423581	TREM2/CSK	2
GO:0032303	regulation of icosanoid secretion	2/1068	21/18722	0.338704789927614	0.526852420423581	SYK/IL1B	2
GO:0034312	diol biosynthetic process	2/1068	21/18722	0.338704789927614	0.526852420423581	ASAH1/ACER3	2
GO:0039702	viral budding via host ESCRT complex	2/1068	21/18722	0.338704789927614	0.526852420423581	CHMP3/CHMP1B	2
GO:0044342	type B pancreatic cell proliferation	2/1068	21/18722	0.338704789927614	0.526852420423581	NUPR1/NR4A1	2
GO:0046519	sphingoid metabolic process	2/1068	21/18722	0.338704789927614	0.526852420423581	ASAH1/ACER3	2
GO:0048745	smooth muscle tissue development	2/1068	21/18722	0.338704789927614	0.526852420423581	ENG/ZFAND5	2
GO:0060445	branching involved in salivary gland morphogenesis	2/1068	21/18722	0.338704789927614	0.526852420423581	HGF/PLXND1	2
GO:0070584	mitochondrion morphogenesis	2/1068	21/18722	0.338704789927614	0.526852420423581	BAX/PLEC	2
GO:0072170	metanephric tubule development	2/1068	21/18722	0.338704789927614	0.526852420423581	STAT1/ACAT1	2
GO:0072243	metanephric nephron epithelium development	2/1068	21/18722	0.338704789927614	0.526852420423581	STAT1/ACAT1	2
GO:0072311	glomerular epithelial cell differentiation	2/1068	21/18722	0.338704789927614	0.526852420423581	NOTCH2/IQGAP1	2
GO:0090141	positive regulation of mitochondrial fission	2/1068	21/18722	0.338704789927614	0.526852420423581	RALA/DDHD1	2
GO:0097734	extracellular exosome biogenesis	2/1068	21/18722	0.338704789927614	0.526852420423581	SDCBP/RAB7A	2
GO:1901863	positive regulation of muscle tissue development	2/1068	21/18722	0.338704789927614	0.526852420423581	MEF2C/FLOT1	2
GO:1902473	regulation of protein localization to synapse	2/1068	21/18722	0.338704789927614	0.526852420423581	RAP1A/ADAM10	2
GO:1903427	negative regulation of reactive oxygen species biosynthetic process	2/1068	21/18722	0.338704789927614	0.526852420423581	RHOA/STAT3	2
GO:1903429	regulation of cell maturation	2/1068	21/18722	0.338704789927614	0.526852420423581	CLEC7A/LRRK2	2
GO:2000774	positive regulation of cellular senescence	2/1068	21/18722	0.338704789927614	0.526852420423581	B2M/ABI3	2
GO:2001014	regulation of skeletal muscle cell differentiation	2/1068	21/18722	0.338704789927614	0.526852420423581	MEF2C/DDX5	2
GO:0072175	epithelial tube formation	9/1068	132/18722	0.339918057324636	0.528587273003958	HIF1A/ST14/TGFB1/VASP/STK4/RALA/PRKACB/SKI/PFN1	9
GO:0006720	isoprenoid metabolic process	8/1068	116/18722	0.342524078077914	0.532486293664196	NPC2/ALDH1A1/SCPEP1/SRD5A3/RDH11/LRP1/DHRS3/DHRS4	8
GO:0016525	negative regulation of angiogenesis	10/1068	149/18722	0.344717847192028	0.534963182224526	STAT1/ALOX5/KLF4/VASH1/STAB1/KLF2/SPRED1/RGCC/PGK1/ROCK1	10
GO:0006664	glycolipid metabolic process	7/1068	100/18722	0.344746390459196	0.534963182224526	GAL3ST4/ST8SIA4/GALC/SCCPDH/HEXA/BAX/GM2A	7
GO:0009062	fatty acid catabolic process	7/1068	100/18722	0.344746390459196	0.534963182224526	ACAA2/ABHD2/ACAT1/CPT1A/PLA2G15/SCP2/HSD17B4	7
GO:0019218	regulation of steroid metabolic process	7/1068	100/18722	0.344746390459196	0.534963182224526	APOE/APOC1/TSPO/ASAH1/ABCG1/EGR1/ATP1A1	7
GO:0051588	regulation of neurotransmitter transport	7/1068	100/18722	0.344746390459196	0.534963182224526	MEF2C/RAP1A/MCTP1/LRRK2/SLC30A1/CALM3/FLOT1	7
GO:0061138	morphogenesis of a branching epithelium	12/1068	182/18722	0.344828265871964	0.534963182224526	CTSZ/CTSH/GRB2/HGF/VEGFA/ST14/PLXND1/ENG/TGFBR2/STK4/SOCS3/PAK1	12
GO:0043090	amino acid import	4/1068	52/18722	0.344910472750023	0.534963182224526	SLC6A6/SFXN3/SLC1A3/RGS2	4
GO:2000378	negative regulation of reactive oxygen species metabolic process	4/1068	52/18722	0.344910472750023	0.534963182224526	ACP5/HIF1A/RHOA/STAT3	4
GO:0006402	mRNA catabolic process	15/1068	232/18722	0.346059279619178	0.536590768053185	VIM/ZFP36L2/ZFP36/SLC11A1/ZFP36L1/YBX1/HSPA1A/PABPC1/MYD88/BTG2/ATM/PABPC4/DDX5/ROCK1/RNH1	15
GO:0061157	mRNA destabilization	6/1068	84/18722	0.346316089145879	0.536834707564253	ZFP36L2/ZFP36/ZFP36L1/PABPC1/BTG2/ROCK1	6
GO:0051148	negative regulation of muscle cell differentiation	5/1068	68/18722	0.346726546244289	0.537162343822619	ID2/YBX1/PAK1/RGS2/BHLHE41	5
GO:0060411	cardiac septum morphogenesis	5/1068	68/18722	0.346726546244289	0.537162343822619	ENG/TGFBR2/NOTCH2/DHRS3/TGFBR1	5
GO:0051236	establishment of RNA localization	11/1068	166/18722	0.348588517254545	0.539737055697424	ZFP36/ZFP36L1/NUP214/YBX1/MX2/TGFBR2/QKI/ATM/NUP62/RANBP2/FLOT1	11
GO:0061013	regulation of mRNA catabolic process	11/1068	166/18722	0.348588517254545	0.539737055697424	VIM/ZFP36L2/ZFP36/SLC11A1/ZFP36L1/YBX1/PABPC1/MYD88/BTG2/PABPC4/ROCK1	11
GO:0003161	cardiac conduction system development	3/1068	37/18722	0.354080635909497	0.545989986796571	ID2/NOTCH2/CDC42	3
GO:0006862	nucleotide transport	3/1068	37/18722	0.354080635909497	0.545989986796571	SLC25A24/SLC25A19/LRRC8C	3
GO:0014904	myotube cell development	3/1068	37/18722	0.354080635909497	0.545989986796571	GPX1/SKI/PLEC	3
GO:0016202	regulation of striated muscle tissue development	3/1068	37/18722	0.354080635909497	0.545989986796571	MEF2C/TGFB1/FLOT1	3
GO:0030513	positive regulation of BMP signaling pathway	3/1068	37/18722	0.354080635909497	0.545989986796571	ENG/NOTCH2/FBXL15	3
GO:0031112	positive regulation of microtubule polymerization or depolymerization	3/1068	37/18722	0.354080635909497	0.545989986796571	HSPA1A/RAC1/PAK1	3
GO:0033120	positive regulation of RNA splicing	3/1068	37/18722	0.354080635909497	0.545989986796571	HSPA1A/SETX/PIK3R1	3
GO:0042401	cellular biogenic amine biosynthetic process	3/1068	37/18722	0.354080635909497	0.545989986796571	NR4A2/OAZ1/SAT1	3
GO:0045616	regulation of keratinocyte differentiation	3/1068	37/18722	0.354080635909497	0.545989986796571	ZFP36/ZFP36L1/ROCK1	3
GO:0062237	protein localization to postsynapse	3/1068	37/18722	0.354080635909497	0.545989986796571	RAP1A/ADAM10/RAB8A	3
GO:0071542	dopaminergic neuron differentiation	3/1068	37/18722	0.354080635909497	0.545989986796571	HIF1A/NR4A2/VEGFA	3
GO:0071985	multivesicular body sorting pathway	3/1068	37/18722	0.354080635909497	0.545989986796571	TMEM50A/CHMP3/CHMP1B	3
GO:0097484	dendrite extension	3/1068	37/18722	0.354080635909497	0.545989986796571	CXCR4/ITSN2/CYFIP1	3
GO:1900077	negative regulation of cellular response to insulin stimulus	3/1068	37/18722	0.354080635909497	0.545989986796571	LPL/SOCS3/IL1B	3
GO:0006476	protein deacetylation	7/1068	101/18722	0.354144728277983	0.545989986796571	FLNA/VEGFA/JDP2/BCL6/SPRED1/LRRK2/SKI	7
GO:0072384	organelle transport along microtubule	6/1068	85/18722	0.356610002418456	0.549633696958009	HIF1A/BLOC1S1/BLOC1S2/LAMP1/CDC42/KIF5B	6
GO:0031279	regulation of cyclase activity	4/1068	53/18722	0.35809054683829	0.550817033387084	TIMP2/GNAI2/CAP1/CALM3	4
GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	4/1068	53/18722	0.35809054683829	0.550817033387084	PLEK/ARRB2/GNAI2/RGS2	4
GO:0003143	embryonic heart tube morphogenesis	5/1068	69/18722	0.358210776769627	0.550817033387084	HIF1A/MEF2C/ENG/TGFBR2/NOTCH2	5
GO:2001257	regulation of cation channel activity	12/1068	184/18722	0.358696347956122	0.550817033387084	TMSB4X/TREM2/CTSS/IFNGR2/MEF2C/KCNE3/PTK2B/DAPK1/CALM3/GSTO1/KLHL24/KIF5B	12
GO:0002053	positive regulation of mesenchymal cell proliferation	2/1068	22/18722	0.359827658022511	0.550817033387084	STAT1/TGFBR2	2
GO:0002320	lymphoid progenitor cell differentiation	2/1068	22/18722	0.359827658022511	0.550817033387084	SPI1/FNIP1	2
GO:0008211	glucocorticoid metabolic process	2/1068	22/18722	0.359827658022511	0.550817033387084	YWHAH/ATP1A1	2
GO:0010866	regulation of triglyceride biosynthetic process	2/1068	22/18722	0.359827658022511	0.550817033387084	C3/NR1H3	2
GO:0033617	mitochondrial cytochrome c oxidase assembly	2/1068	22/18722	0.359827658022511	0.550817033387084	SCO2/OXA1L	2
GO:0034629	cellular protein-containing complex localization	2/1068	22/18722	0.359827658022511	0.550817033387084	TNFAIP2/RCC2	2
GO:0035561	regulation of chromatin binding	2/1068	22/18722	0.359827658022511	0.550817033387084	PARP9/DTX3L	2
GO:0042430	indole-containing compound metabolic process	2/1068	22/18722	0.359827658022511	0.550817033387084	IL4I1/KYNU	2
GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	2/1068	22/18722	0.359827658022511	0.550817033387084	RUNX1/BCL6	2
GO:0044346	fibroblast apoptotic process	2/1068	22/18722	0.359827658022511	0.550817033387084	BID/BTG1	2
GO:0045540	regulation of cholesterol biosynthetic process	2/1068	22/18722	0.359827658022511	0.550817033387084	APOE/ABCG1	2
GO:0045663	positive regulation of myoblast differentiation	2/1068	22/18722	0.359827658022511	0.550817033387084	MEF2C/BTG1	2
GO:0060563	neuroepithelial cell differentiation	2/1068	22/18722	0.359827658022511	0.550817033387084	FAM20C/CEBPB	2
GO:0071467	cellular response to pH	2/1068	22/18722	0.359827658022511	0.550817033387084	HVCN1/MCOLN1	2
GO:0090280	positive regulation of calcium ion import	2/1068	22/18722	0.359827658022511	0.550817033387084	CCL3/LGALS3	2
GO:0106118	regulation of sterol biosynthetic process	2/1068	22/18722	0.359827658022511	0.550817033387084	APOE/ABCG1	2
GO:1901032	negative regulation of response to reactive oxygen species	2/1068	22/18722	0.359827658022511	0.550817033387084	HGF/LRRK2	2
GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	2/1068	22/18722	0.359827658022511	0.550817033387084	HIF1A/VEGFA	2
GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	2/1068	22/18722	0.359827658022511	0.550817033387084	HMOX1/VEGFA	2
GO:2000193	positive regulation of fatty acid transport	2/1068	22/18722	0.359827658022511	0.550817033387084	ACSL1/IL1B	2
GO:2000181	negative regulation of blood vessel morphogenesis	10/1068	151/18722	0.360069114853929	0.551030330048724	STAT1/ALOX5/KLF4/VASH1/STAB1/KLF2/SPRED1/RGCC/PGK1/ROCK1	10
GO:0006403	RNA localization	13/1068	201/18722	0.361014298497342	0.552320145929021	ZFP36/ZFP36L1/NUP214/YBX1/MX2/TGFBR2/QKI/ATM/NOP10/ZNF385A/NUP62/RANBP2/FLOT1	13
GO:0062014	negative regulation of small molecule metabolic process	7/1068	102/18722	0.363567319083433	0.556068382589061	APOE/APOC1/NUPR1/PLEK/FBP1/DDIT4/STAT3	7
GO:0007369	gastrulation	12/1068	185/18722	0.365662804089096	0.559114902483639	ITGB2/DUSP1/MBP/KLF4/TGFBR2/MYADM/ITGA4/MMP2/ITGA5/DUSP2/PRKAR1A/WNK1	12
GO:0046928	regulation of neurotransmitter secretion	6/1068	86/18722	0.366924041487293	0.560884455485958	MEF2C/RAP1A/MCTP1/LRRK2/SLC30A1/CALM3	6
GO:1901343	negative regulation of vasculature development	10/1068	152/18722	0.367778628015021	0.56203157087767	STAT1/ALOX5/KLF4/VASH1/STAB1/KLF2/SPRED1/RGCC/PGK1/ROCK1	10
GO:0008210	estrogen metabolic process	3/1068	38/18722	0.369920916865946	0.56386815463521	HSD17B11/SGPL1/HSD17B4	3
GO:0009309	amine biosynthetic process	3/1068	38/18722	0.369920916865946	0.56386815463521	NR4A2/OAZ1/SAT1	3
GO:0010613	positive regulation of cardiac muscle hypertrophy	3/1068	38/18722	0.369920916865946	0.56386815463521	HAMP/MEF2A/ROCK1	3
GO:0032717	negative regulation of interleukin-8 production	3/1068	38/18722	0.369920916865946	0.56386815463521	TMSB4X/KLF4/CD33	3
GO:0032941	secretion by tissue	3/1068	38/18722	0.369920916865946	0.56386815463521	CYBA/NR1H3/WNK1	3
GO:0035886	vascular associated smooth muscle cell differentiation	3/1068	38/18722	0.369920916865946	0.56386815463521	SOD2/VEGFA/ENG	3
GO:0046329	negative regulation of JNK cascade	3/1068	38/18722	0.369920916865946	0.56386815463521	TAOK3/SIRPA/DUSP3	3
GO:0048713	regulation of oligodendrocyte differentiation	3/1068	38/18722	0.369920916865946	0.56386815463521	CXCR4/TLR2/TNFRSF1B	3
GO:0051930	regulation of sensory perception of pain	3/1068	38/18722	0.369920916865946	0.56386815463521	FABP5/CCL3/PTAFR	3
GO:0000075	cell cycle checkpoint signaling	11/1068	169/18722	0.370487813414801	0.564413393897872	DUSP1/TAOK3/PLK3/CDKN1A/RNASEH2B/RPS27L/ATM/FOXN3/APC/DYNC1LI1/TAOK1	11
GO:0021543	pallium development	11/1068	169/18722	0.370487813414801	0.564413393897872	PHACTR1/HIF1A/BCL2A1/FLNA/RHOA/ZMIZ1/BTG2/LRP1/RTN4/BAX/KIF5B	11
GO:0006584	catecholamine metabolic process	4/1068	54/18722	0.371265184825507	0.564641188646684	ITGB2/NR4A2/ITGAM/HPRT1	4
GO:0007215	glutamate receptor signaling pathway	4/1068	54/18722	0.371265184825507	0.564641188646684	HOMER3/PRNP/PTK2B/GNAQ	4
GO:0009712	catechol-containing compound metabolic process	4/1068	54/18722	0.371265184825507	0.564641188646684	ITGB2/NR4A2/ITGAM/HPRT1	4
GO:0010524	positive regulation of calcium ion transport into cytosol	4/1068	54/18722	0.371265184825507	0.564641188646684	P2RX7/CALM3/GSTO1/BAX	4
GO:0043647	inositol phosphate metabolic process	4/1068	54/18722	0.371265184825507	0.564641188646684	PLEK/NUDT3/PTAFR/PTK2B	4
GO:0072698	protein localization to microtubule cytoskeleton	4/1068	54/18722	0.371265184825507	0.564641188646684	SNX10/APC/NUP62/CEP350	4
GO:0019395	fatty acid oxidation	7/1068	103/18722	0.373008348967964	0.567132446049911	PDK4/ACAA2/PRKAG2/ACAT1/CPT1A/SCP2/HSD17B4	7
GO:0016101	diterpenoid metabolic process	6/1068	87/18722	0.377250707347895	0.573098202941791	ALDH1A1/SCPEP1/RDH11/LRP1/DHRS3/DHRS4	6
GO:0044070	regulation of anion transport	6/1068	87/18722	0.377250707347895	0.573098202941791	SYK/PRNP/PTAFR/IL1B/CEBPB/RGS2	6
GO:0061014	positive regulation of mRNA catabolic process	6/1068	87/18722	0.377250707347895	0.573098202941791	ZFP36L2/ZFP36/ZFP36L1/PABPC1/BTG2/ROCK1	6
GO:0001919	regulation of receptor recycling	2/1068	23/18722	0.380694921663151	0.574770508476318	ARAP1/RAB29	2
GO:0002052	positive regulation of neuroblast proliferation	2/1068	23/18722	0.380694921663151	0.574770508476318	HIF1A/VEGFA	2
GO:0006541	glutamine metabolic process	2/1068	23/18722	0.380694921663151	0.574770508476318	GLUL/GLS	2
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	2/1068	23/18722	0.380694921663151	0.574770508476318	PTPRJ/LRP1	2
GO:0019430	removal of superoxide radicals	2/1068	23/18722	0.380694921663151	0.574770508476318	SOD2/CD36	2
GO:0030194	positive regulation of blood coagulation	2/1068	23/18722	0.380694921663151	0.574770508476318	CD36/HPSE	2
GO:0031338	regulation of vesicle fusion	2/1068	23/18722	0.380694921663151	0.574770508476318	CORO1A/KIF5B	2
GO:0034105	positive regulation of tissue remodeling	2/1068	23/18722	0.380694921663151	0.574770508476318	IL18/ROCK1	2
GO:0034695	response to prostaglandin E	2/1068	23/18722	0.380694921663151	0.574770508476318	PTGER4/GNB1	2
GO:0036303	lymph vessel morphogenesis	2/1068	23/18722	0.380694921663151	0.574770508476318	VEGFA/VASH1	2
GO:0042026	protein refolding	2/1068	23/18722	0.380694921663151	0.574770508476318	B2M/HSPA1A	2
GO:0043931	ossification involved in bone maturation	2/1068	23/18722	0.380694921663151	0.574770508476318	SNX10/RHOA	2
GO:0045662	negative regulation of myoblast differentiation	2/1068	23/18722	0.380694921663151	0.574770508476318	IL18/TGFB1	2
GO:0045932	negative regulation of muscle contraction	2/1068	23/18722	0.380694921663151	0.574770508476318	DOCK4/RGS2	2
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	2/1068	23/18722	0.380694921663151	0.574770508476318	DSE/CSGALNACT2	2
GO:0060353	regulation of cell adhesion molecule production	2/1068	23/18722	0.380694921663151	0.574770508476318	IL1B/FLOT1	2
GO:0060547	negative regulation of necrotic cell death	2/1068	23/18722	0.380694921663151	0.574770508476318	NUPR1/ARHGEF2	2
GO:0071218	cellular response to misfolded protein	2/1068	23/18722	0.380694921663151	0.574770508476318	UBE2W/SDF2L1	2
GO:0071636	positive regulation of transforming growth factor beta production	2/1068	23/18722	0.380694921663151	0.574770508476318	LGALS9/ATP6AP2	2
GO:0140112	extracellular vesicle biogenesis	2/1068	23/18722	0.380694921663151	0.574770508476318	SDCBP/RAB7A	2
GO:1900048	positive regulation of hemostasis	2/1068	23/18722	0.380694921663151	0.574770508476318	CD36/HPSE	2
GO:2000737	negative regulation of stem cell differentiation	2/1068	23/18722	0.380694921663151	0.574770508476318	ZFP36L2/STAT3	2
GO:0050795	regulation of behavior	5/1068	71/18722	0.381205050937489	0.57537970765278	APOE/CCL3/MEF2C/RETN/STAT3	5
GO:0003229	ventricular cardiac muscle tissue development	4/1068	55/18722	0.384419730157203	0.579745350455077	ID2/TGFB1/ENG/TGFBR1	4
GO:0042220	response to cocaine	4/1068	55/18722	0.384419730157203	0.579745350455077	HNMT/PTK2B/SLC1A3/UBE3A	4
GO:0048016	inositol phosphate-mediated signaling	4/1068	55/18722	0.384419730157203	0.579745350455077	CLEC7A/HOMER3/CIB1/PRNP	4
GO:0014742	positive regulation of muscle hypertrophy	3/1068	39/18722	0.385688145788085	0.580522520131801	HAMP/MEF2A/ROCK1	3
GO:0016572	histone phosphorylation	3/1068	39/18722	0.385688145788085	0.580522520131801	JAK2/IL1B/ATM	3
GO:0043267	negative regulation of potassium ion transport	3/1068	39/18722	0.385688145788085	0.580522520131801	KCNE3/PTK2B/CAB39	3
GO:0051931	regulation of sensory perception	3/1068	39/18722	0.385688145788085	0.580522520131801	FABP5/CCL3/PTAFR	3
GO:0071548	response to dexamethasone	3/1068	39/18722	0.385688145788085	0.580522520131801	DDIT4/PTAFR/NR3C1	3
GO:0090224	regulation of spindle organization	3/1068	39/18722	0.385688145788085	0.580522520131801	HSPA1A/NUP62/CHMP1B	3
GO:1901861	regulation of muscle tissue development	3/1068	39/18722	0.385688145788085	0.580522520131801	MEF2C/TGFB1/FLOT1	3
GO:0001704	formation of primary germ layer	8/1068	121/18722	0.38620319447986	0.580973637416594	ITGB2/DUSP1/KLF4/ITGA4/MMP2/ITGA5/DUSP2/PRKAR1A	8
GO:0003206	cardiac chamber morphogenesis	8/1068	121/18722	0.38620319447986	0.580973637416594	HIF1A/MEF2C/TGFB1/ENG/TGFBR2/NOTCH2/DHRS3/TGFBR1	8
GO:0034249	negative regulation of cellular amide metabolic process	17/1068	273/18722	0.390139337316776	0.586731288785208	APOE/SORL1/ZFP36L2/ZFP36/ZFP36L1/YBX1/PABPC1/EIF4EBP1/PRNP/BTG2/STAT3/EIF2AK2/DAPK1/RTN4/ROCK1/RTN3/RGS2	17
GO:0040029	regulation of gene expression, epigenetic	7/1068	105/18722	0.391922892066976	0.589249352352578	GPX1/IFI16/SPI1/ZMIZ1/XIST/KLF2/ARID4A	7
GO:0033045	regulation of sister chromatid segregation	5/1068	72/18722	0.392695116648252	0.590081550942347	DUSP1/RB1/ATM/APC/DYNC1LI1	5
GO:0051057	positive regulation of small GTPase mediated signal transduction	5/1068	72/18722	0.392695116648252	0.590081550942347	GPR65/LPAR6/NOTCH2/RAC1/AKAP13	5
GO:0005996	monosaccharide metabolic process	16/1068	257/18722	0.395837727388288	0.594638189584411	FABP5/SDS/FBP1/PDK4/OAS1/FUOM/SLC2A3/ADPGK/AKR1A1/SERP1/CPT1A/PGK1/GSTO1/GAA/ATF3/RANBP2	16
GO:0046622	positive regulation of organ growth	4/1068	56/18722	0.397540138427105	0.596863268489888	HAMP/MEF2C/SASH3/SERP1	4
GO:0051653	spindle localization	4/1068	56/18722	0.397540138427105	0.596863268489888	ACTR2/ACTR3/CFL1/KPNB1	4
GO:0002021	response to dietary excess	2/1068	24/18722	0.40126701490789	0.598601462540745	APOE/SORL1	2
GO:0003148	outflow tract septum morphogenesis	2/1068	24/18722	0.40126701490789	0.598601462540745	ENG/TGFBR2	2
GO:0006817	phosphate ion transport	2/1068	24/18722	0.40126701490789	0.598601462540745	SLC37A2/CEBPB	2
GO:0016048	detection of temperature stimulus	2/1068	24/18722	0.40126701490789	0.598601462540745	CXCR4/ARRB2	2
GO:0016486	peptide hormone processing	2/1068	24/18722	0.40126701490789	0.598601462540745	CTSZ/ATP6AP2	2
GO:0021801	cerebral cortex radial glia-guided migration	2/1068	24/18722	0.40126701490789	0.598601462540745	ZMIZ1/RTN4	2
GO:0022030	telencephalon glial cell migration	2/1068	24/18722	0.40126701490789	0.598601462540745	ZMIZ1/RTN4	2
GO:0048011	neurotrophin TRK receptor signaling pathway	2/1068	24/18722	0.40126701490789	0.598601462540745	DDIT4/CYFIP1	2
GO:0050820	positive regulation of coagulation	2/1068	24/18722	0.40126701490789	0.598601462540745	CD36/HPSE	2
GO:0070841	inclusion body assembly	2/1068	24/18722	0.40126701490789	0.598601462540745	SORL1/HSPA1A	2
GO:0070935	3'-UTR-mediated mRNA stabilization	2/1068	24/18722	0.40126701490789	0.598601462540745	ZFP36/MYD88	2
GO:0071577	zinc ion transmembrane transport	2/1068	24/18722	0.40126701490789	0.598601462540745	TRPM2/SLC30A1	2
GO:0072530	purine-containing compound transmembrane transport	2/1068	24/18722	0.40126701490789	0.598601462540745	AQP9/LRRC8C	2
GO:0090343	positive regulation of cell aging	2/1068	24/18722	0.40126701490789	0.598601462540745	B2M/ABI3	2
GO:1903861	positive regulation of dendrite extension	2/1068	24/18722	0.40126701490789	0.598601462540745	CXCR4/ITSN2	2
GO:2000353	positive regulation of endothelial cell apoptotic process	2/1068	24/18722	0.40126701490789	0.598601462540745	ITGA4/RGCC	2
GO:0006730	one-carbon metabolic process	3/1068	40/18722	0.401360283816237	0.598601462540745	SFXN3/MTHFD2/MAT2A	3
GO:0031297	replication fork processing	3/1068	40/18722	0.401360283816237	0.598601462540745	SAMHD1/FAM111A/BOD1L1	3
GO:0035329	hippo signaling	3/1068	40/18722	0.401360283816237	0.598601462540745	MOB1A/STK4/PJA2	3
GO:0044275	cellular carbohydrate catabolic process	3/1068	40/18722	0.401360283816237	0.598601462540745	AOAH/SCARB2/GAA	3
GO:0045740	positive regulation of DNA replication	3/1068	40/18722	0.401360283816237	0.598601462540745	JUN/RAC1/CDC42	3
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	3/1068	40/18722	0.401360283816237	0.598601462540745	CALM3/GSTO1/BAX	3
GO:0055081	anion homeostasis	3/1068	40/18722	0.401360283816237	0.598601462540745	TBXAS1/GLS/KCNE3	3
GO:1901661	quinone metabolic process	3/1068	40/18722	0.401360283816237	0.598601462540745	NQO2/VKORC1/AKR1A1	3
GO:0006813	potassium ion transport	15/1068	241/18722	0.401817204390561	0.599117334869153	TREM2/CD63/FLNA/PRNP/KCNAB2/KCNE3/ATP1B1/PTK2B/CAB39/SLC1A3/KLHL24/WNK1/KIF5B/ATP1B3/ATP1A1	15
GO:0003231	cardiac ventricle development	8/1068	123/18722	0.403763139321043	0.601520126939908	HIF1A/MEF2C/TGFB1/ENG/TGFBR2/PRDM1/CNTRL/TGFBR1	8
GO:0031570	DNA integrity checkpoint signaling	8/1068	123/18722	0.403763139321043	0.601520126939908	TAOK3/PLK3/CDKN1A/RNASEH2B/RPS27L/ATM/FOXN3/TAOK1	8
GO:0071482	cellular response to light stimulus	8/1068	123/18722	0.403763139321043	0.601520126939908	TIMP1/CARD16/CRIP1/MMP2/CDKN1A/ERCC1/BAX/PIK3R1	8
GO:0051145	smooth muscle cell differentiation	5/1068	73/18722	0.404167641933833	0.601790451400377	SOD2/MEF2C/VEGFA/ENG/PIAS1	5
GO:0072089	stem cell proliferation	5/1068	73/18722	0.404167641933833	0.601790451400377	ZFP36L1/PTPRC/RUNX1/ETV6/EIF2AK2	5
GO:0030177	positive regulation of Wnt signaling pathway	9/1068	140/18722	0.405408086730333	0.603470906481897	ZEB2/TLR2/ATP6AP2/TGFB1/LRRK2/TNFAIP3/SKI/XIAP/WNK1	9
GO:0006836	neurotransmitter transport	13/1068	208/18722	0.408025514595211	0.607199579910579	PPT1/MEF2C/RAP1A/MCTP1/SLC6A6/LRRK2/SLC30A1/STXBP2/STX4/CALM3/SLC1A3/NR4A1/FLOT1	13
GO:0050879	multicellular organismal movement	4/1068	57/18722	0.410612987939123	0.610376772154135	RCSD1/GSTO1/NR4A1/GAA	4
GO:0050881	musculoskeletal movement	4/1068	57/18722	0.410612987939123	0.610376772154135	RCSD1/GSTO1/NR4A1/GAA	4
GO:0051155	positive regulation of striated muscle cell differentiation	4/1068	57/18722	0.410612987939123	0.610376772154135	HAMP/MEF2C/ARRB2/TGFB1	4
GO:0051785	positive regulation of nuclear division	4/1068	57/18722	0.410612987939123	0.610376772154135	RB1/IL1B/RGCC/NUP62	4
GO:0006275	regulation of DNA replication	7/1068	107/18722	0.410843637803748	0.610551437507304	CCDC88A/JUN/SLFN11/BCL6/RAC1/CDC42/S100A11	7
GO:0032355	response to estradiol	9/1068	141/18722	0.413638945513184	0.614536274776747	TXNIP/DUSP1/TGFB1/BID/NCOR2/GPX4/ARPC1B/STAT3/MBD4	9
GO:0006635	fatty acid beta-oxidation	5/1068	74/18722	0.415613393437837	0.617299716760409	ACAA2/ACAT1/CPT1A/SCP2/HSD17B4	5
GO:0048634	regulation of muscle organ development	3/1068	41/18722	0.416916831669333	0.618894972128671	MEF2C/TGFB1/FLOT1	3
GO:0060612	adipose tissue development	3/1068	41/18722	0.416916831669333	0.618894972128671	SORL1/SPI1/ACAT1	3
GO:0019935	cyclic-nucleotide-mediated signaling	6/1068	91/18722	0.418539120431956	0.621132314040383	APOE/CD36/AHR/PTK2B/CAP1/RGS2	6
GO:0006958	complement activation, classical pathway	7/1068	108/18722	0.420292812240446	0.621813604312659	C1QB/TREM2/C3/C1QA/C1QC/C2/SERPING1	7
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	2/1068	25/18722	0.421509708974658	0.621813604312659	CYBA/RHOA	2
GO:0010954	positive regulation of protein processing	2/1068	25/18722	0.421509708974658	0.621813604312659	ADAM8/GSN	2
GO:0010996	response to auditory stimulus	2/1068	25/18722	0.421509708974658	0.621813604312659	ABHD12/SLC1A3	2
GO:0016540	protein autoprocessing	2/1068	25/18722	0.421509708974658	0.621813604312659	CASP1/FAM111A	2
GO:0033119	negative regulation of RNA splicing	2/1068	25/18722	0.421509708974658	0.621813604312659	TMBIM6/PTBP3	2
GO:0035336	long-chain fatty-acyl-CoA metabolic process	2/1068	25/18722	0.421509708974658	0.621813604312659	ACSL1/ACSL4	2
GO:0042730	fibrinolysis	2/1068	25/18722	0.421509708974658	0.621813604312659	PLAU/SERPING1	2
GO:0045822	negative regulation of heart contraction	2/1068	25/18722	0.421509708974658	0.621813604312659	JAK2/ATP1A1	2
GO:0046835	carbohydrate phosphorylation	2/1068	25/18722	0.421509708974658	0.621813604312659	NAGK/GNPTG	2
GO:0050927	positive regulation of positive chemotaxis	2/1068	25/18722	0.421509708974658	0.621813604312659	VEGFA/VEGFB	2
GO:0050951	sensory perception of temperature stimulus	2/1068	25/18722	0.421509708974658	0.621813604312659	CXCR4/ARRB2	2
GO:0051788	response to misfolded protein	2/1068	25/18722	0.421509708974658	0.621813604312659	UBE2W/SDF2L1	2
GO:0062149	detection of stimulus involved in sensory perception of pain	2/1068	25/18722	0.421509708974658	0.621813604312659	CXCR4/ARRB2	2
GO:0071450	cellular response to oxygen radical	2/1068	25/18722	0.421509708974658	0.621813604312659	SOD2/CD36	2
GO:0071451	cellular response to superoxide	2/1068	25/18722	0.421509708974658	0.621813604312659	SOD2/CD36	2
GO:0071459	protein localization to chromosome, centromeric region	2/1068	25/18722	0.421509708974658	0.621813604312659	RB1/RCC2	2
GO:0072207	metanephric epithelium development	2/1068	25/18722	0.421509708974658	0.621813604312659	STAT1/ACAT1	2
GO:0090169	regulation of spindle assembly	2/1068	25/18722	0.421509708974658	0.621813604312659	HSPA1A/CHMP1B	2
GO:1902932	positive regulation of alcohol biosynthetic process	2/1068	25/18722	0.421509708974658	0.621813604312659	PTAFR/ABCG1	2
GO:2000316	regulation of T-helper 17 type immune response	2/1068	25/18722	0.421509708974658	0.621813604312659	CLEC7A/NFKBIZ	2
GO:0007623	circadian rhythm	13/1068	210/18722	0.42153338854257	0.621813604312659	ID2/JUN/ATF5/AHR/NR1H3/NAMPT/SETX/BHLHE40/KLF10/GNAQ/UBE3A/EGR1/BHLHE41	13
GO:0072006	nephron development	9/1068	142/18722	0.42186756945341	0.622136486682318	STAT1/MEF2C/PECAM1/VEGFA/NOTCH2/IL6R/ACAT1/IQGAP1/EGR1	9
GO:0046488	phosphatidylinositol metabolic process	10/1068	159/18722	0.422083001586456	0.62228411927883	PLEK/CSF1R/LPGAT1/INPP5D/SOCS3/MTMR6/EFR3A/ATM/PIK3R1/SOCS6	10
GO:0009161	ribonucleoside monophosphate metabolic process	4/1068	58/18722	0.423625486855574	0.623706173826106	UPP1/DPYD/IMPDH1/HPRT1	4
GO:0032387	negative regulation of intracellular transport	4/1068	58/18722	0.423625486855574	0.623706173826106	CD36/SP100/MDFIC/LRRK2	4
GO:0043506	regulation of JUN kinase activity	4/1068	58/18722	0.423625486855574	0.623706173826106	TAOK3/SYK/PTK2B/PAK1	4
GO:0044380	protein localization to cytoskeleton	4/1068	58/18722	0.423625486855574	0.623706173826106	SNX10/APC/NUP62/CEP350	4
GO:1902808	positive regulation of cell cycle G1/S phase transition	4/1068	58/18722	0.423625486855574	0.623706173826106	AIF1/KMT2E/RGCC/ADAM17	4
GO:0006094	gluconeogenesis	5/1068	75/18722	0.427023458074906	0.628194814550762	SDS/FBP1/PGK1/ATF3/RANBP2	5
GO:0008088	axo-dendritic transport	5/1068	75/18722	0.427023458074906	0.628194814550762	HIF1A/BLOC1S1/BLOC1S2/ARL8B/KIF5B	5
GO:1902369	negative regulation of RNA catabolic process	5/1068	75/18722	0.427023458074906	0.628194814550762	ZFP36/SLC11A1/YBX1/PABPC1/MYD88	5
GO:0031058	positive regulation of histone modification	6/1068	92/18722	0.42882202542714	0.630496907140286	VEGFA/JDP2/BCL6/LRRK2/KMT2E/IL1B	6
GO:0032465	regulation of cytokinesis	6/1068	92/18722	0.42882202542714	0.630496907140286	RHOA/PLK3/CALM3/NUP62/CDC42/CHMP3	6
GO:0006821	chloride transport	7/1068	109/18722	0.429727533923597	0.631484142987944	TSPO/PRNP/PTAFR/TTYH3/SLC1A3/CLIC1/CLCN7	7
GO:0072009	nephron epithelium development	7/1068	109/18722	0.429727533923597	0.631484142987944	STAT1/MEF2C/PECAM1/VEGFA/NOTCH2/ACAT1/IQGAP1	7
GO:0035637	multicellular organismal signaling	10/1068	160/18722	0.429852054407357	0.631495149899836	TYMP/MEF2A/SLC8A1/FLNA/OTOA/KCNE3/ATP1B1/CALM3/ATP1A1/PLEC	10
GO:0006865	amino acid transport	9/1068	143/18722	0.430090449234288	0.631673397949978	SLC11A1/SLC7A7/SLC38A6/LRRC8C/SLC6A6/SFXN3/MFSD12/SLC1A3/RGS2	9
GO:0009154	purine ribonucleotide catabolic process	3/1068	42/18722	0.432338794785821	0.633564108841132	NUDT3/HPRT1/ACAT1	3
GO:0014003	oligodendrocyte development	3/1068	42/18722	0.432338794785821	0.633564108841132	CD9/LYN/TLR2	3
GO:0021795	cerebral cortex cell migration	3/1068	42/18722	0.432338794785821	0.633564108841132	RHOA/ZMIZ1/RTN4	3
GO:0021879	forebrain neuron differentiation	3/1068	42/18722	0.432338794785821	0.633564108841132	B2M/ZMIZ1/ZSWIM6	3
GO:0045214	sarcomere organization	3/1068	42/18722	0.432338794785821	0.633564108841132	PRKAR1A/AKAP13/PLEC	3
GO:0060999	positive regulation of dendritic spine development	3/1068	42/18722	0.432338794785821	0.633564108841132	APOE/ACTR2/DBNL	3
GO:0071312	cellular response to alkaloid	3/1068	42/18722	0.432338794785821	0.633564108841132	AIF1/SLC8A1/SLC1A3	3
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	3/1068	42/18722	0.432338794785821	0.633564108841132	RHOA/KLF4/SPRED1	3
GO:0071806	protein transmembrane transport	4/1068	59/18722	0.436565477205409	0.633564108841132	MCL1/ABCA1/TRAM1/TMED10	4
GO:0060349	bone morphogenesis	6/1068	93/18722	0.43907603847981	0.633564108841132	ACP5/MEF2C/TGFBR2/DHRS3/FOXN3/SKI	6
GO:1901992	positive regulation of mitotic cell cycle phase transition	6/1068	93/18722	0.43907603847981	0.633564108841132	AIF1/RB1/KMT2E/RGCC/ADAM17/RCC2	6
GO:0003014	renal system process	7/1068	110/18722	0.439142713320141	0.633564108841132	CYBA/SGK1/LGMN/GNAI2/RHOA/PRKACB/GSN	7
GO:0001963	synaptic transmission, dopaminergic	2/1068	26/18722	0.441393633038411	0.633564108841132	ARRB2/FLOT1	2
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	2/1068	26/18722	0.441393633038411	0.633564108841132	SSR3/TRAM1	2
GO:0008535	respiratory chain complex IV assembly	2/1068	26/18722	0.441393633038411	0.633564108841132	SCO2/OXA1L	2
GO:0042537	benzene-containing compound metabolic process	2/1068	26/18722	0.441393633038411	0.633564108841132	KYNU/FAH	2
GO:0046639	negative regulation of alpha-beta T cell differentiation	2/1068	26/18722	0.441393633038411	0.633564108841132	RUNX1/BCL6	2
GO:0046755	viral budding	2/1068	26/18722	0.441393633038411	0.633564108841132	CHMP3/CHMP1B	2
GO:0048499	synaptic vesicle membrane organization	2/1068	26/18722	0.441393633038411	0.633564108841132	SYNGR2/STX4	2
GO:0048668	collateral sprouting	2/1068	26/18722	0.441393633038411	0.633564108841132	SPP1/LRP1	2
GO:0050926	regulation of positive chemotaxis	2/1068	26/18722	0.441393633038411	0.633564108841132	VEGFA/VEGFB	2
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	2/1068	26/18722	0.441393633038411	0.633564108841132	CALM3/GSTO1	2
GO:0060352	cell adhesion molecule production	2/1068	26/18722	0.441393633038411	0.633564108841132	IL1B/FLOT1	2
GO:0070977	bone maturation	2/1068	26/18722	0.441393633038411	0.633564108841132	SNX10/RHOA	2
GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	2/1068	26/18722	0.441393633038411	0.633564108841132	GNAI2/AKAP13	2
GO:1901071	glucosamine-containing compound metabolic process	2/1068	26/18722	0.441393633038411	0.633564108841132	GNPDA1/NAGK	2
GO:1903523	negative regulation of blood circulation	2/1068	26/18722	0.441393633038411	0.633564108841132	JAK2/ATP1A1	2
GO:1904353	regulation of telomere capping	2/1068	26/18722	0.441393633038411	0.633564108841132	ERCC1/ATM	2
GO:1905063	regulation of vascular associated smooth muscle cell differentiation	2/1068	26/18722	0.441393633038411	0.633564108841132	SOD2/ENG	2
GO:0045664	regulation of neuron differentiation	12/1068	196/18722	0.443000933077152	0.633564108841132	B2M/YWHAH/ID2/TIMP2/MEF2C/DPYSL2/RHOA/BCL6/LRRK2/ARHGEF2/ROCK1/YWHAG	12
GO:0000050	urea cycle	1/1068	10/18722	0.444293289076138	0.633564108841132	CEBPA	1
GO:0006171	cAMP biosynthetic process	1/1068	10/18722	0.444293289076138	0.633564108841132	ADCY7	1
GO:0006222	UMP biosynthetic process	1/1068	10/18722	0.444293289076138	0.633564108841132	UPP1	1
GO:0006547	histidine metabolic process	1/1068	10/18722	0.444293289076138	0.633564108841132	HNMT	1
GO:0006646	phosphatidylethanolamine biosynthetic process	1/1068	10/18722	0.444293289076138	0.633564108841132	CEPT1	1
GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	1/1068	10/18722	0.444293289076138	0.633564108841132	GNB1	1
GO:0008300	isoprenoid catabolic process	1/1068	10/18722	0.444293289076138	0.633564108841132	SRD5A3	1
GO:0009113	purine nucleobase biosynthetic process	1/1068	10/18722	0.444293289076138	0.633564108841132	HPRT1	1
GO:0009169	purine ribonucleoside monophosphate catabolic process	1/1068	10/18722	0.444293289076138	0.633564108841132	HPRT1	1
GO:0009174	pyrimidine ribonucleoside monophosphate biosynthetic process	1/1068	10/18722	0.444293289076138	0.633564108841132	UPP1	1
GO:0010944	negative regulation of transcription by competitive promoter binding	1/1068	10/18722	0.444293289076138	0.633564108841132	BHLHE41	1
GO:0010992	ubiquitin recycling	1/1068	10/18722	0.444293289076138	0.633564108841132	RNF135	1
GO:0014041	regulation of neuron maturation	1/1068	10/18722	0.444293289076138	0.633564108841132	LRRK2	1
GO:0019062	virion attachment to host cell	1/1068	10/18722	0.444293289076138	0.633564108841132	CD81	1
GO:0021903	rostrocaudal neural tube patterning	1/1068	10/18722	0.444293289076138	0.633564108841132	ATP6AP2	1
GO:0021932	hindbrain radial glia guided cell migration	1/1068	10/18722	0.444293289076138	0.633564108841132	FLNA	1
GO:0030388	fructose 1,6-bisphosphate metabolic process	1/1068	10/18722	0.444293289076138	0.633564108841132	FBP1	1
GO:0030638	polyketide metabolic process	1/1068	10/18722	0.444293289076138	0.633564108841132	AKR1A1	1
GO:0030647	aminoglycoside antibiotic metabolic process	1/1068	10/18722	0.444293289076138	0.633564108841132	AKR1A1	1
GO:0030953	astral microtubule organization	1/1068	10/18722	0.444293289076138	0.633564108841132	KPNB1	1
GO:0031118	rRNA pseudouridine synthesis	1/1068	10/18722	0.444293289076138	0.633564108841132	NOP10	1
GO:0031340	positive regulation of vesicle fusion	1/1068	10/18722	0.444293289076138	0.633564108841132	KIF5B	1
GO:0031642	negative regulation of myelination	1/1068	10/18722	0.444293289076138	0.633564108841132	CTSC	1
GO:0031848	protection from non-homologous end joining at telomere	1/1068	10/18722	0.444293289076138	0.633564108841132	ERCC1	1
GO:0031943	regulation of glucocorticoid metabolic process	1/1068	10/18722	0.444293289076138	0.633564108841132	ATP1A1	1
GO:0032380	regulation of intracellular sterol transport	1/1068	10/18722	0.444293289076138	0.633564108841132	SCP2	1
GO:0032383	regulation of intracellular cholesterol transport	1/1068	10/18722	0.444293289076138	0.633564108841132	SCP2	1
GO:0033080	immature T cell proliferation in thymus	1/1068	10/18722	0.444293289076138	0.633564108841132	IL1B	1
GO:0033089	positive regulation of T cell differentiation in thymus	1/1068	10/18722	0.444293289076138	0.633564108841132	ADAM8	1
GO:0033131	regulation of glucokinase activity	1/1068	10/18722	0.444293289076138	0.633564108841132	RANBP2	1
GO:0033572	transferrin transport	1/1068	10/18722	0.444293289076138	0.633564108841132	MCOLN1	1
GO:0034085	establishment of sister chromatid cohesion	1/1068	10/18722	0.444293289076138	0.633564108841132	RB1	1
GO:0035871	protein K11-linked deubiquitination	1/1068	10/18722	0.444293289076138	0.633564108841132	TNFAIP3	1
GO:0035907	dorsal aorta development	1/1068	10/18722	0.444293289076138	0.633564108841132	ENG	1
GO:0035999	tetrahydrofolate interconversion	1/1068	10/18722	0.444293289076138	0.633564108841132	MTHFD2	1
GO:0036109	alpha-linolenic acid metabolic process	1/1068	10/18722	0.444293289076138	0.633564108841132	SCP2	1
GO:0038007	netrin-activated signaling pathway	1/1068	10/18722	0.444293289076138	0.633564108841132	SHTN1	1
GO:0040015	negative regulation of multicellular organism growth	1/1068	10/18722	0.444293289076138	0.633564108841132	LGMN	1
GO:0042368	vitamin D biosynthetic process	1/1068	10/18722	0.444293289076138	0.633564108841132	CYP27A1	1
GO:0043101	purine-containing compound salvage	1/1068	10/18722	0.444293289076138	0.633564108841132	HPRT1	1
GO:0044598	doxorubicin metabolic process	1/1068	10/18722	0.444293289076138	0.633564108841132	AKR1A1	1
GO:0045050	protein insertion into ER membrane by stop-transfer membrane-anchor sequence	1/1068	10/18722	0.444293289076138	0.633564108841132	EMC3	1
GO:0045792	negative regulation of cell size	1/1068	10/18722	0.444293289076138	0.633564108841132	RHOA	1
GO:0045835	negative regulation of meiotic nuclear division	1/1068	10/18722	0.444293289076138	0.633564108841132	PRKAR1A	1
GO:0045843	negative regulation of striated muscle tissue development	1/1068	10/18722	0.444293289076138	0.633564108841132	TGFB1	1
GO:0048194	Golgi vesicle budding	1/1068	10/18722	0.444293289076138	0.633564108841132	TMED10	1
GO:0048671	negative regulation of collateral sprouting	1/1068	10/18722	0.444293289076138	0.633564108841132	SPP1	1
GO:0048672	positive regulation of collateral sprouting	1/1068	10/18722	0.444293289076138	0.633564108841132	LRP1	1
GO:0051006	positive regulation of lipoprotein lipase activity	1/1068	10/18722	0.444293289076138	0.633564108841132	NR1H3	1
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	1/1068	10/18722	0.444293289076138	0.633564108841132	CALM3	1
GO:0051351	positive regulation of ligase activity	1/1068	10/18722	0.444293289076138	0.633564108841132	TMSB4X	1
GO:0051409	response to nitrosative stress	1/1068	10/18722	0.444293289076138	0.633564108841132	ATM	1
GO:0060439	trachea morphogenesis	1/1068	10/18722	0.444293289076138	0.633564108841132	TGFBR2	1
GO:0060947	cardiac vascular smooth muscle cell differentiation	1/1068	10/18722	0.444293289076138	0.633564108841132	VEGFA	1
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	1/1068	10/18722	0.444293289076138	0.633564108841132	UCP2	1
GO:0090037	positive regulation of protein kinase C signaling	1/1068	10/18722	0.444293289076138	0.633564108841132	VEGFA	1
GO:0097278	complement-dependent cytotoxicity	1/1068	10/18722	0.444293289076138	0.633564108841132	C3	1
GO:0098917	retrograde trans-synaptic signaling	1/1068	10/18722	0.444293289076138	0.633564108841132	FABP5	1
GO:0099639	neurotransmitter receptor transport, endosome to plasma membrane	1/1068	10/18722	0.444293289076138	0.633564108841132	RAB8A	1
GO:0140059	dendrite arborization	1/1068	10/18722	0.444293289076138	0.633564108841132	PHACTR1	1
GO:0150172	regulation of phosphatidylcholine metabolic process	1/1068	10/18722	0.444293289076138	0.633564108841132	APOC1	1
GO:1901524	regulation of mitophagy	1/1068	10/18722	0.444293289076138	0.633564108841132	VPS13C	1
GO:1901978	positive regulation of cell cycle checkpoint	1/1068	10/18722	0.444293289076138	0.633564108841132	DYNC1LI1	1
GO:1902023	L-arginine transport	1/1068	10/18722	0.444293289076138	0.633564108841132	SLC11A1	1
GO:1902224	ketone body metabolic process	1/1068	10/18722	0.444293289076138	0.633564108841132	ACAT1	1
GO:1902513	regulation of organelle transport along microtubule	1/1068	10/18722	0.444293289076138	0.633564108841132	LAMP1	1
GO:1903867	extraembryonic membrane development	1/1068	10/18722	0.444293289076138	0.633564108841132	HTRA1	1
GO:1904896	ESCRT complex disassembly	1/1068	10/18722	0.444293289076138	0.633564108841132	CHMP1B	1
GO:1904903	ESCRT III complex disassembly	1/1068	10/18722	0.444293289076138	0.633564108841132	CHMP1B	1
GO:1905383	protein localization to presynapse	1/1068	10/18722	0.444293289076138	0.633564108841132	KIF5B	1
GO:1905456	regulation of lymphoid progenitor cell differentiation	1/1068	10/18722	0.444293289076138	0.633564108841132	FNIP1	1
GO:1905809	negative regulation of synapse organization	1/1068	10/18722	0.444293289076138	0.633564108841132	TLR2	1
GO:1905941	positive regulation of gonad development	1/1068	10/18722	0.444293289076138	0.633564108841132	RETN	1
GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	1/1068	10/18722	0.444293289076138	0.633564108841132	UBE3A	1
GO:1990535	neuron projection maintenance	1/1068	10/18722	0.444293289076138	0.633564108841132	PRNP	1
GO:2000121	regulation of removal of superoxide radicals	1/1068	10/18722	0.444293289076138	0.633564108841132	CD36	1
GO:2000252	negative regulation of feeding behavior	1/1068	10/18722	0.444293289076138	0.633564108841132	RETN	1
GO:2000288	positive regulation of myoblast proliferation	1/1068	10/18722	0.444293289076138	0.633564108841132	MALAT1	1
GO:2000434	regulation of protein neddylation	1/1068	10/18722	0.444293289076138	0.633564108841132	HIF1A	1
GO:2001223	negative regulation of neuron migration	1/1068	10/18722	0.444293289076138	0.633564108841132	STAT3	1
GO:0010498	proteasomal protein catabolic process	29/1068	490/18722	0.446127951004535	0.636012265157324	APOE/GPX1/TREM2/IFI27/NUPR1/PSMB9/PSMB8/ARRB2/SDCBP/HSPA1A/PLK3/LRRK2/GABARAP/PSMB10/MAN1A1/FBXL15/HM13/UBE2W/CEBPA/CANX/HERPUD1/PIAS1/PSME2/UBE2D3/CAMLG/SUMO2/SOCS6/PCBP2/SDF2L1	29
GO:0014014	negative regulation of gliogenesis	3/1068	43/18722	0.447608643517715	0.637449522412666	TREM2/TSPO/SKI	3
GO:0140353	lipid export from cell	3/1068	43/18722	0.447608643517715	0.637449522412666	SPP1/RETN/IL1B	3
GO:1903793	positive regulation of anion transport	3/1068	43/18722	0.447608643517715	0.637449522412666	PTAFR/IL1B/CEBPB	3
GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	3/1068	43/18722	0.447608643517715	0.637449522412666	HSPA1A/MCL1/IL1B	3
GO:0044262	cellular carbohydrate metabolic process	17/1068	283/18722	0.44876345018849	0.638925482115328	NUPR1/PLEK/FBP1/PDK4/DDIT4/PTAFR/AOAH/CSGALNACT2/SCARB2/PRKAG2/PTK2B/STAT3/NAGK/GAA/GNPTG/RANBP2/B3GNT2	17
GO:0001738	morphogenesis of a polarized epithelium	6/1068	94/18722	0.449294892635933	0.63951338450633	ACTB/MSN/RHOA/RAC1/CDC42/RAB10	6
GO:0006081	cellular aldehyde metabolic process	4/1068	60/18722	0.449421436016042	0.639524807157848	ALDH1A1/RDH11/PDXK/AKR1A1	4
GO:0050657	nucleic acid transport	10/1068	163/18722	0.45311074190412	0.644434782107178	ZFP36/ZFP36L1/NUP214/YBX1/MX2/TGFBR2/QKI/NUP62/RANBP2/FLOT1	10
GO:0050658	RNA transport	10/1068	163/18722	0.45311074190412	0.644434782107178	ZFP36/ZFP36L1/NUP214/YBX1/MX2/TGFBR2/QKI/NUP62/RANBP2/FLOT1	10
GO:0048167	regulation of synaptic plasticity	12/1068	198/18722	0.457063883452211	0.649885827432973	APOE/TYROBP/YWHAH/LGMN/MEF2C/PRNP/LILRB2/MCTP1/PTK2B/STX4/RAB8A/YWHAG	12
GO:0000956	nuclear-transcribed mRNA catabolic process	7/1068	112/18722	0.457894723951104	0.650895661338293	ZFP36L2/ZFP36/ZFP36L1/PABPC1/BTG2/ATM/DDX5	7
GO:0048709	oligodendrocyte differentiation	6/1068	95/18722	0.459472523541932	0.651470686789409	CD9/CXCR4/LYN/TLR2/TNFRSF1B/CSK	6
GO:0000737	DNA catabolic process, endonucleolytic	2/1068	27/18722	0.46089383225181	0.651470686789409	DNASE2/BAX	2
GO:0001835	blastocyst hatching	2/1068	27/18722	0.46089383225181	0.651470686789409	LPAR6/CMTM3	2
GO:0007628	adult walking behavior	2/1068	27/18722	0.46089383225181	0.651470686789409	ARRB2/ABHD12	2
GO:0008053	mitochondrial fusion	2/1068	27/18722	0.46089383225181	0.651470686789409	VAT1/BAX	2
GO:0010528	regulation of transposition	2/1068	27/18722	0.46089383225181	0.651470686789409	APOBEC3C/APOBEC3A	2
GO:0010529	negative regulation of transposition	2/1068	27/18722	0.46089383225181	0.651470686789409	APOBEC3C/APOBEC3A	2
GO:0010894	negative regulation of steroid biosynthetic process	2/1068	27/18722	0.46089383225181	0.651470686789409	APOE/ATP1A1	2
GO:0014850	response to muscle activity	2/1068	27/18722	0.46089383225181	0.651470686789409	HIF1A/METRNL	2
GO:0034505	tooth mineralization	2/1068	27/18722	0.46089383225181	0.651470686789409	TCIRG1/FAM20C	2
GO:0035188	hatching	2/1068	27/18722	0.46089383225181	0.651470686789409	LPAR6/CMTM3	2
GO:0035459	vesicle cargo loading	2/1068	27/18722	0.46089383225181	0.651470686789409	TMED10/PICALM	2
GO:0039529	RIG-I signaling pathway	2/1068	27/18722	0.46089383225181	0.651470686789409	OAS3/RNF135	2
GO:0042104	positive regulation of activated T cell proliferation	2/1068	27/18722	0.46089383225181	0.651470686789409	PYCARD/IL18	2
GO:0046337	phosphatidylethanolamine metabolic process	2/1068	27/18722	0.46089383225181	0.651470686789409	CEPT1/PLA2G15	2
GO:0071684	organism emergence from protective structure	2/1068	27/18722	0.46089383225181	0.651470686789409	LPAR6/CMTM3	2
GO:1903205	regulation of hydrogen peroxide-induced cell death	2/1068	27/18722	0.46089383225181	0.651470686789409	HGF/LRRK2	2
GO:1903319	positive regulation of protein maturation	2/1068	27/18722	0.46089383225181	0.651470686789409	ADAM8/GSN	2
GO:1903859	regulation of dendrite extension	2/1068	27/18722	0.46089383225181	0.651470686789409	CXCR4/ITSN2	2
GO:0009064	glutamine family amino acid metabolic process	5/1068	78/18722	0.460955352513337	0.651470686789409	GLUL/SLC7A7/DDAH2/GLS/FAH	5
GO:0019319	hexose biosynthetic process	5/1068	78/18722	0.460955352513337	0.651470686789409	SDS/FBP1/PGK1/ATF3/RANBP2	5
GO:0035050	embryonic heart tube development	5/1068	78/18722	0.460955352513337	0.651470686789409	HIF1A/MEF2C/ENG/TGFBR2/NOTCH2	5
GO:0006900	vesicle budding from membrane	4/1068	61/18722	0.462182473821517	0.652413016204403	TMED10/PICALM/RAB7A/S100A10	4
GO:0019748	secondary metabolic process	4/1068	61/18722	0.462182473821517	0.652413016204403	ZEB2/MFSD12/AKR1A1/APPL1	4
GO:0040014	regulation of multicellular organism growth	4/1068	61/18722	0.462182473821517	0.652413016204403	LGMN/STAT5A/SGPL1/STAT3	4
GO:0050994	regulation of lipid catabolic process	4/1068	61/18722	0.462182473821517	0.652413016204403	APOC1/SORL1/IL1B/CPT1A	4
GO:0002066	columnar/cuboidal epithelial cell development	3/1068	44/18722	0.462710269276177	0.652413016204403	HIF1A/PRDM1/CDKN1A	3
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	3/1068	44/18722	0.462710269276177	0.652413016204403	MSN/RHOA/CDC42	3
GO:0051150	regulation of smooth muscle cell differentiation	3/1068	44/18722	0.462710269276177	0.652413016204403	SOD2/ENG/PIAS1	3
GO:0089718	amino acid import across plasma membrane	3/1068	44/18722	0.462710269276177	0.652413016204403	SLC6A6/SLC1A3/RGS2	3
GO:1903214	regulation of protein targeting to mitochondrion	3/1068	44/18722	0.462710269276177	0.652413016204403	LRRK2/BNIP3L/UBE2D3	3
GO:0016331	morphogenesis of embryonic epithelium	9/1068	147/18722	0.46285641438966	0.652448592488664	HIF1A/ST14/TGFB1/VASP/STK4/RALA/PRKACB/SKI/PFN1	9
GO:0051304	chromosome separation	6/1068	96/18722	0.46960307373017	0.653243470498459	DUSP1/RB1/PLSCR1/ATM/APC/DYNC1LI1	6
GO:0043484	regulation of RNA splicing	9/1068	148/18722	0.47100004819087	0.653243470498459	MBNL1/TMBIM6/HSPA1A/CELF2/QKI/SETX/DDX5/PTBP3/PIK3R1	9
GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	4/1068	62/18722	0.474838330788602	0.653243470498459	RAP1A/NUMB/ADAM10/RAB8A	4
GO:0001660	fever generation	1/1068	11/18722	0.476010623795393	0.653243470498459	IL1B	1
GO:0001731	formation of translation preinitiation complex	1/1068	11/18722	0.476010623795393	0.653243470498459	EIF2S3	1
GO:0001967	suckling behavior	1/1068	11/18722	0.476010623795393	0.653243470498459	GLS	1
GO:0002759	regulation of antimicrobial humoral response	1/1068	11/18722	0.476010623795393	0.653243470498459	PPP2R3C	1
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	1/1068	11/18722	0.476010623795393	0.653243470498459	PTPN6	1
GO:0003093	regulation of glomerular filtration	1/1068	11/18722	0.476010623795393	0.653243470498459	CYBA	1
GO:0003139	secondary heart field specification	1/1068	11/18722	0.476010623795393	0.653243470498459	MEF2C	1
GO:0003157	endocardium development	1/1068	11/18722	0.476010623795393	0.653243470498459	STK4	1
GO:0006002	fructose 6-phosphate metabolic process	1/1068	11/18722	0.476010623795393	0.653243470498459	FBP1	1
GO:0006086	acetyl-CoA biosynthetic process from pyruvate	1/1068	11/18722	0.476010623795393	0.653243470498459	PDK4	1
GO:0006183	GTP biosynthetic process	1/1068	11/18722	0.476010623795393	0.653243470498459	IMPDH1	1
GO:0006188	IMP biosynthetic process	1/1068	11/18722	0.476010623795393	0.653243470498459	HPRT1	1
GO:0006702	androgen biosynthetic process	1/1068	11/18722	0.476010623795393	0.653243470498459	SRD5A3	1
GO:0008611	ether lipid biosynthetic process	1/1068	11/18722	0.476010623795393	0.653243470498459	LPCAT2	1
GO:0009128	purine nucleoside monophosphate catabolic process	1/1068	11/18722	0.476010623795393	0.653243470498459	HPRT1	1
GO:0009155	purine deoxyribonucleotide catabolic process	1/1068	11/18722	0.476010623795393	0.653243470498459	SAMHD1	1
GO:0009313	oligosaccharide catabolic process	1/1068	11/18722	0.476010623795393	0.653243470498459	GM2A	1
GO:0010918	positive regulation of mitochondrial membrane potential	1/1068	11/18722	0.476010623795393	0.653243470498459	BID	1
GO:0010986	positive regulation of lipoprotein particle clearance	1/1068	11/18722	0.476010623795393	0.653243470498459	TREM2	1
GO:0014010	Schwann cell proliferation	1/1068	11/18722	0.476010623795393	0.653243470498459	SKI	1
GO:0015810	aspartate transmembrane transport	1/1068	11/18722	0.476010623795393	0.653243470498459	LRRC8C	1
GO:0015937	coenzyme A biosynthetic process	1/1068	11/18722	0.476010623795393	0.653243470498459	ACAT1	1
GO:0019048	modulation by virus of host process	1/1068	11/18722	0.476010623795393	0.653243470498459	CD4	1
GO:0021860	pyramidal neuron development	1/1068	11/18722	0.476010623795393	0.653243470498459	ZMIZ1	1
GO:0021889	olfactory bulb interneuron differentiation	1/1068	11/18722	0.476010623795393	0.653243470498459	ATF5	1
GO:0031652	positive regulation of heat generation	1/1068	11/18722	0.476010623795393	0.653243470498459	IL1B	1
GO:0032000	positive regulation of fatty acid beta-oxidation	1/1068	11/18722	0.476010623795393	0.653243470498459	CPT1A	1
GO:0032308	positive regulation of prostaglandin secretion	1/1068	11/18722	0.476010623795393	0.653243470498459	IL1B	1
GO:0032329	serine transport	1/1068	11/18722	0.476010623795393	0.653243470498459	SFXN3	1
GO:0032351	negative regulation of hormone metabolic process	1/1068	11/18722	0.476010623795393	0.653243470498459	ATP1A1	1
GO:0032377	regulation of intracellular lipid transport	1/1068	11/18722	0.476010623795393	0.653243470498459	SCP2	1
GO:0032610	interleukin-1 alpha production	1/1068	11/18722	0.476010623795393	0.653243470498459	CASP1	1
GO:0032650	regulation of interleukin-1 alpha production	1/1068	11/18722	0.476010623795393	0.653243470498459	CASP1	1
GO:0033033	negative regulation of myeloid cell apoptotic process	1/1068	11/18722	0.476010623795393	0.653243470498459	IRF7	1
GO:0033083	regulation of immature T cell proliferation	1/1068	11/18722	0.476010623795393	0.653243470498459	IL1B	1
GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	1/1068	11/18722	0.476010623795393	0.653243470498459	PAK1	1
GO:0033210	leptin-mediated signaling pathway	1/1068	11/18722	0.476010623795393	0.653243470498459	STAT3	1
GO:0033625	positive regulation of integrin activation	1/1068	11/18722	0.476010623795393	0.653243470498459	PLEK	1
GO:0033690	positive regulation of osteoblast proliferation	1/1068	11/18722	0.476010623795393	0.653243470498459	HPSE	1
GO:0034350	regulation of glial cell apoptotic process	1/1068	11/18722	0.476010623795393	0.653243470498459	TREM2	1
GO:0034770	histone H4-K20 methylation	1/1068	11/18722	0.476010623795393	0.653243470498459	ARID4A	1
GO:0042135	neurotransmitter catabolic process	1/1068	11/18722	0.476010623795393	0.653243470498459	HNMT	1
GO:0042416	dopamine biosynthetic process	1/1068	11/18722	0.476010623795393	0.653243470498459	NR4A2	1
GO:0042451	purine nucleoside biosynthetic process	1/1068	11/18722	0.476010623795393	0.653243470498459	HPRT1	1
GO:0042455	ribonucleoside biosynthetic process	1/1068	11/18722	0.476010623795393	0.653243470498459	HPRT1	1
GO:0044068	modulation by symbiont of host cellular process	1/1068	11/18722	0.476010623795393	0.653243470498459	CD4	1
GO:0045793	positive regulation of cell size	1/1068	11/18722	0.476010623795393	0.653243470498459	TMEM123	1
GO:0045945	positive regulation of transcription by RNA polymerase III	1/1068	11/18722	0.476010623795393	0.653243470498459	CEBPA	1
GO:0046129	purine ribonucleoside biosynthetic process	1/1068	11/18722	0.476010623795393	0.653243470498459	HPRT1	1
GO:0046349	amino sugar biosynthetic process	1/1068	11/18722	0.476010623795393	0.653243470498459	GNPDA1	1
GO:0046504	glycerol ether biosynthetic process	1/1068	11/18722	0.476010623795393	0.653243470498459	LPCAT2	1
GO:0048096	chromatin-mediated maintenance of transcription	1/1068	11/18722	0.476010623795393	0.653243470498459	ZMIZ1	1
GO:0048103	somatic stem cell division	1/1068	11/18722	0.476010623795393	0.653243470498459	ZFP36L2	1
GO:0048635	negative regulation of muscle organ development	1/1068	11/18722	0.476010623795393	0.653243470498459	TGFB1	1
GO:0051386	regulation of neurotrophin TRK receptor signaling pathway	1/1068	11/18722	0.476010623795393	0.653243470498459	CYFIP1	1
GO:0051561	positive regulation of mitochondrial calcium ion concentration	1/1068	11/18722	0.476010623795393	0.653243470498459	MICU1	1
GO:0051798	positive regulation of hair follicle development	1/1068	11/18722	0.476010623795393	0.653243470498459	HPSE	1
GO:0055015	ventricular cardiac muscle cell development	1/1068	11/18722	0.476010623795393	0.653243470498459	MEF2A	1
GO:0060159	regulation of dopamine receptor signaling pathway	1/1068	11/18722	0.476010623795393	0.653243470498459	LRRK2	1
GO:0060433	bronchus development	1/1068	11/18722	0.476010623795393	0.653243470498459	TGFBR2	1
GO:0060742	epithelial cell differentiation involved in prostate gland development	1/1068	11/18722	0.476010623795393	0.653243470498459	PSAP	1
GO:0061314	Notch signaling involved in heart development	1/1068	11/18722	0.476010623795393	0.653243470498459	NOTCH2	1
GO:0061365	positive regulation of triglyceride lipase activity	1/1068	11/18722	0.476010623795393	0.653243470498459	NR1H3	1
GO:0061635	regulation of protein complex stability	1/1068	11/18722	0.476010623795393	0.653243470498459	TAPBP	1
GO:0070189	kynurenine metabolic process	1/1068	11/18722	0.476010623795393	0.653243470498459	KYNU	1
GO:0070341	fat cell proliferation	1/1068	11/18722	0.476010623795393	0.653243470498459	TREM2	1
GO:0070344	regulation of fat cell proliferation	1/1068	11/18722	0.476010623795393	0.653243470498459	TREM2	1
GO:0070778	L-aspartate transmembrane transport	1/1068	11/18722	0.476010623795393	0.653243470498459	SLC1A3	1
GO:0071044	histone mRNA catabolic process	1/1068	11/18722	0.476010623795393	0.653243470498459	ATM	1
GO:0071313	cellular response to caffeine	1/1068	11/18722	0.476010623795393	0.653243470498459	SLC8A1	1
GO:0071679	commissural neuron axon guidance	1/1068	11/18722	0.476010623795393	0.653243470498459	VEGFA	1
GO:0075522	IRES-dependent viral translational initiation	1/1068	11/18722	0.476010623795393	0.653243470498459	PCBP2	1
GO:0090030	regulation of steroid hormone biosynthetic process	1/1068	11/18722	0.476010623795393	0.653243470498459	ATP1A1	1
GO:0090205	positive regulation of cholesterol metabolic process	1/1068	11/18722	0.476010623795393	0.653243470498459	ABCG1	1
GO:0090394	negative regulation of excitatory postsynaptic potential	1/1068	11/18722	0.476010623795393	0.653243470498459	LRRK2	1
GO:0090649	response to oxygen-glucose deprivation	1/1068	11/18722	0.476010623795393	0.653243470498459	NAMPT	1
GO:0097384	cellular lipid biosynthetic process	1/1068	11/18722	0.476010623795393	0.653243470498459	LPCAT2	1
GO:0098935	dendritic transport	1/1068	11/18722	0.476010623795393	0.653243470498459	KIF5B	1
GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	1/1068	11/18722	0.476010623795393	0.653243470498459	NUMB	1
GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration	1/1068	11/18722	0.476010623795393	0.653243470498459	SLC8A1	1
GO:0099624	atrial cardiac muscle cell membrane repolarization	1/1068	11/18722	0.476010623795393	0.653243470498459	FLNA	1
GO:0106072	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	1/1068	11/18722	0.476010623795393	0.653243470498459	GNAI2	1
GO:1900222	negative regulation of amyloid-beta clearance	1/1068	11/18722	0.476010623795393	0.653243470498459	IFNGR1	1
GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	1/1068	11/18722	0.476010623795393	0.653243470498459	CHCHD10	1
GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction	1/1068	11/18722	0.476010623795393	0.653243470498459	CALM3	1
GO:1901862	negative regulation of muscle tissue development	1/1068	11/18722	0.476010623795393	0.653243470498459	TGFB1	1
GO:1902033	regulation of hematopoietic stem cell proliferation	1/1068	11/18722	0.476010623795393	0.653243470498459	EIF2AK2	1
GO:1902065	response to L-glutamate	1/1068	11/18722	0.476010623795393	0.653243470498459	TMBIM6	1
GO:1902188	positive regulation of viral release from host cell	1/1068	11/18722	0.476010623795393	0.653243470498459	CHMP3	1
GO:1902510	regulation of apoptotic DNA fragmentation	1/1068	11/18722	0.476010623795393	0.653243470498459	BAX	1
GO:1902667	regulation of axon guidance	1/1068	11/18722	0.476010623795393	0.653243470498459	VEGFA	1
GO:1903299	regulation of hexokinase activity	1/1068	11/18722	0.476010623795393	0.653243470498459	RANBP2	1
GO:1903423	positive regulation of synaptic vesicle recycling	1/1068	11/18722	0.476010623795393	0.653243470498459	LRRK2	1
GO:1903897	regulation of PERK-mediated unfolded protein response	1/1068	11/18722	0.476010623795393	0.653243470498459	PPP1R15A	1
GO:1903961	positive regulation of anion transmembrane transport	1/1068	11/18722	0.476010623795393	0.653243470498459	PTAFR	1
GO:1904181	positive regulation of membrane depolarization	1/1068	11/18722	0.476010623795393	0.653243470498459	TSPO	1
GO:1904321	response to forskolin	1/1068	11/18722	0.476010623795393	0.653243470498459	AHR	1
GO:1904322	cellular response to forskolin	1/1068	11/18722	0.476010623795393	0.653243470498459	AHR	1
GO:1905150	regulation of voltage-gated sodium channel activity	1/1068	11/18722	0.476010623795393	0.653243470498459	KIF5B	1
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	1/1068	11/18722	0.476010623795393	0.653243470498459	FLOT1	1
GO:2001053	regulation of mesenchymal cell apoptotic process	1/1068	11/18722	0.476010623795393	0.653243470498459	HIF1A	1
GO:0019751	polyol metabolic process	7/1068	114/18722	0.476510732689287	0.653763517312838	ASAH1/PLEK/NUDT3/CYP27A1/PTAFR/PTK2B/ACER3	7
GO:0008654	phospholipid biosynthetic process	15/1068	253/18722	0.476899973761066	0.654131229896978	FABP5/PLSCR1/LPCAT2/AGPAT2/LPGAT1/INPP5D/SRD5A3/SOCS3/MTMR6/EFR3A/ATM/CEPT1/SERINC1/PIK3R1/SOCS6	15
GO:0003197	endocardial cushion development	3/1068	45/18722	0.477628937428276	0.654133438163192	ENG/TGFBR2/TGFBR1	3
GO:0003254	regulation of membrane depolarization	3/1068	45/18722	0.477628937428276	0.654133438163192	TSPO/LRRK2/PPP2R3C	3
GO:0010824	regulation of centrosome duplication	3/1068	45/18722	0.477628937428276	0.654133438163192	NUP62/CHMP3/CHMP1B	3
GO:0022602	ovulation cycle process	3/1068	45/18722	0.477628937428276	0.654133438163192	ARRB2/RETN/SGPL1	3
GO:0030850	prostate gland development	3/1068	45/18722	0.477628937428276	0.654133438163192	PSAP/CRIP1/UBE3A	3
GO:0031670	cellular response to nutrient	3/1068	45/18722	0.477628937428276	0.654133438163192	HMOX1/LPL/USF2	3
GO:0009411	response to UV	9/1068	149/18722	0.479118189683652	0.654376601369649	GPX1/TIMP1/CARD16/CRIP1/MMP2/CDKN1A/ERCC1/BAX/PIK3R1	9
GO:0006721	terpenoid metabolic process	6/1068	97/18722	0.479680896185958	0.654376601369649	ALDH1A1/SCPEP1/RDH11/LRP1/DHRS3/DHRS4	6
GO:0043255	regulation of carbohydrate biosynthetic process	6/1068	97/18722	0.479680896185958	0.654376601369649	PLEK/FBP1/TGFB1/PTAFR/PTK2B/RANBP2	6
GO:0070252	actin-mediated cell contraction	6/1068	97/18722	0.479680896185958	0.654376601369649	FLNA/KCNE3/SHTN1/GSN/MYL6/ATP1A1	6
GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	2/1068	28/18722	0.479989360307834	0.654376601369649	UBE2W/SDF2L1	2
GO:0006829	zinc ion transport	2/1068	28/18722	0.479989360307834	0.654376601369649	TRPM2/SLC30A1	2
GO:0010464	regulation of mesenchymal cell proliferation	2/1068	28/18722	0.479989360307834	0.654376601369649	STAT1/TGFBR2	2
GO:0015740	C4-dicarboxylate transport	2/1068	28/18722	0.479989360307834	0.654376601369649	LRRC8C/SLC1A3	2
GO:0030262	apoptotic nuclear changes	2/1068	28/18722	0.479989360307834	0.654376601369649	DNASE2/BAX	2
GO:0050996	positive regulation of lipid catabolic process	2/1068	28/18722	0.479989360307834	0.654376601369649	IL1B/CPT1A	2
GO:0051503	adenine nucleotide transport	2/1068	28/18722	0.479989360307834	0.654376601369649	SLC25A24/LRRC8C	2
GO:0060259	regulation of feeding behavior	2/1068	28/18722	0.479989360307834	0.654376601369649	RETN/STAT3	2
GO:0060765	regulation of androgen receptor signaling pathway	2/1068	28/18722	0.479989360307834	0.654376601369649	NCOR2/DDX5	2
GO:0071280	cellular response to copper ion	2/1068	28/18722	0.479989360307834	0.654376601369649	PRNP/MT1X	2
GO:0080111	DNA demethylation	2/1068	28/18722	0.479989360307834	0.654376601369649	APOBEC3C/APOBEC3A	2
GO:0090659	walking behavior	2/1068	28/18722	0.479989360307834	0.654376601369649	ARRB2/ABHD12	2
GO:0099623	regulation of cardiac muscle cell membrane repolarization	2/1068	28/18722	0.479989360307834	0.654376601369649	FLNA/KCNE3	2
GO:1903671	negative regulation of sprouting angiogenesis	2/1068	28/18722	0.479989360307834	0.654376601369649	ALOX5/KLF2	2
GO:0071805	potassium ion transmembrane transport	13/1068	219/18722	0.482150896991056	0.657157423633174	TREM2/CD63/FLNA/PRNP/KCNAB2/KCNE3/ATP1B1/CAB39/SLC1A3/KLHL24/WNK1/ATP1B3/ATP1A1	13
GO:0051303	establishment of chromosome localization	5/1068	80/18722	0.483249771019053	0.658488829398689	ACTR2/ACTR3/NUP62/KPNB1/CHMP1B	5
GO:0008544	epidermis development	19/1068	324/18722	0.484499671926225	0.66002530414388	HLA-DRB1/FABP5/TXNIP/ASAH1/ZFP36/ZFP36L1/YBX1/SLC4A7/KLF4/ST14/WAS/AGPAT2/HPSE/ATP2C1/STK4/ADAM9/CSTA/ROCK1/PLEC	19
GO:0009913	epidermal cell differentiation	12/1068	202/18722	0.485043795673828	0.660433086413317	TXNIP/ASAH1/ZFP36/ZFP36L1/SLC4A7/KLF4/ST14/STK4/ADAM9/CSTA/ROCK1/PLEC	12
GO:0016051	carbohydrate biosynthetic process	12/1068	202/18722	0.485043795673828	0.660433086413317	PLEK/SDS/FBP1/TGFB1/PTAFR/CSGALNACT2/PTK2B/AKR1A1/PGK1/ATF3/RANBP2/B3GNT2	12
GO:0019318	hexose metabolic process	14/1068	237/18722	0.485883883616605	0.661410049443794	FABP5/SDS/FBP1/PDK4/OAS1/FUOM/ADPGK/AKR1A1/SERP1/CPT1A/PGK1/GAA/ATF3/RANBP2	14
GO:0016239	positive regulation of macroautophagy	4/1068	63/18722	0.487379370690826	0.663278457565624	HMOX1/HIF1A/BNIP3L/SESN3	4
GO:0006984	ER-nucleus signaling pathway	3/1068	46/18722	0.492351237654852	0.669200825789818	BID/TMCO1/PPP1R15A	3
GO:0031648	protein destabilization	3/1068	46/18722	0.492351237654852	0.669200825789818	CTSH/PRNP/GSN	3
GO:0032924	activin receptor signaling pathway	3/1068	46/18722	0.492351237654852	0.669200825789818	TGFBR2/TGFBR1/SKI	3
GO:0043616	keratinocyte proliferation	3/1068	46/18722	0.492351237654852	0.669200825789818	ZFP36/ZFP36L1/NOTCH2	3
GO:0055010	ventricular cardiac muscle tissue morphogenesis	3/1068	46/18722	0.492351237654852	0.669200825789818	TGFB1/ENG/TGFBR1	3
GO:2000243	positive regulation of reproductive process	5/1068	81/18722	0.494277248704515	0.671241793363661	LHFPL2/RETN/CIB1/VEGFA/PTAFR	5
GO:2001021	negative regulation of response to DNA damage stimulus	5/1068	81/18722	0.494277248704515	0.671241793363661	CD74/CD44/BID/ERCC1/ZNF385A	5
GO:0003209	cardiac atrium morphogenesis	2/1068	29/18722	0.498662904047368	0.671241793363661	ENG/NOTCH2	2
GO:0006656	phosphatidylcholine biosynthetic process	2/1068	29/18722	0.498662904047368	0.671241793363661	FABP5/CEPT1	2
GO:0009218	pyrimidine ribonucleotide metabolic process	2/1068	29/18722	0.498662904047368	0.671241793363661	UPP1/DPYD	2
GO:0015701	bicarbonate transport	2/1068	29/18722	0.498662904047368	0.671241793363661	SLC4A7/CYB5R4	2
GO:0015868	purine ribonucleotide transport	2/1068	29/18722	0.498662904047368	0.671241793363661	SLC25A24/LRRC8C	2
GO:0019433	triglyceride catabolic process	2/1068	29/18722	0.498662904047368	0.671241793363661	SORL1/LPL	2
GO:0022011	myelination in peripheral nervous system	2/1068	29/18722	0.498662904047368	0.671241793363661	SKI/PLEC	2
GO:0030970	retrograde protein transport, ER to cytosol	2/1068	29/18722	0.498662904047368	0.671241793363661	HM13/HERPUD1	2
GO:0032292	peripheral nervous system axon ensheathment	2/1068	29/18722	0.498662904047368	0.671241793363661	SKI/PLEC	2
GO:0034311	diol metabolic process	2/1068	29/18722	0.498662904047368	0.671241793363661	ASAH1/ACER3	2
GO:0043153	entrainment of circadian clock by photoperiod	2/1068	29/18722	0.498662904047368	0.671241793363661	ID2/BHLHE40	2
GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	2/1068	29/18722	0.498662904047368	0.671241793363661	RGCC/ADAM17	2
GO:0051873	killing by host of symbiont cells	2/1068	29/18722	0.498662904047368	0.671241793363661	TREM1/MYD88	2
GO:0051883	killing of cells in other organism involved in symbiotic interaction	2/1068	29/18722	0.498662904047368	0.671241793363661	TREM1/MYD88	2
GO:0060441	epithelial tube branching involved in lung morphogenesis	2/1068	29/18722	0.498662904047368	0.671241793363661	CTSZ/CTSH	2
GO:0070979	protein K11-linked ubiquitination	2/1068	29/18722	0.498662904047368	0.671241793363661	UBE2W/UBE2D3	2
GO:0071549	cellular response to dexamethasone stimulus	2/1068	29/18722	0.498662904047368	0.671241793363661	DDIT4/NR3C1	2
GO:1901017	negative regulation of potassium ion transmembrane transporter activity	2/1068	29/18722	0.498662904047368	0.671241793363661	KCNE3/CAB39	2
GO:1903513	endoplasmic reticulum to cytosol transport	2/1068	29/18722	0.498662904047368	0.671241793363661	HM13/HERPUD1	2
GO:2001032	regulation of double-strand break repair via nonhomologous end joining	2/1068	29/18722	0.498662904047368	0.671241793363661	PARP9/DTX3L	2
GO:0006937	regulation of muscle contraction	10/1068	169/18722	0.499159781137891	0.671241793363661	SLC8A1/DOCK4/RHOA/PTAFR/ATP1B1/CALM3/GSTO1/NR4A1/RGS2/ATP1A1	10
GO:0006940	regulation of smooth muscle contraction	4/1068	64/18722	0.499796572948912	0.671241793363661	DOCK4/RHOA/PTAFR/RGS2	4
GO:0016126	sterol biosynthetic process	4/1068	64/18722	0.499796572948912	0.671241793363661	APOE/ACAA2/PRKAG2/ABCG1	4
GO:0015931	nucleobase-containing compound transport	13/1068	222/18722	0.50213894988795	0.671241793363661	ZFP36/ZFP36L1/NUP214/YBX1/SLC25A24/MX2/SLC25A19/TGFBR2/LRRC8C/QKI/NUP62/RANBP2/FLOT1	13
GO:0032886	regulation of microtubule-based process	14/1068	240/18722	0.505104236460396	0.671241793363661	RHOA/CIB1/ATF5/HSPA1A/ARHGEF2/RAC1/ROCK1/APC/PAK1/NUP62/LAMP1/TAOK1/CHMP3/CHMP1B	14
GO:0016575	histone deacetylation	5/1068	82/18722	0.505216075228619	0.671241793363661	VEGFA/JDP2/BCL6/LRRK2/SKI	5
GO:0050000	chromosome localization	5/1068	82/18722	0.505216075228619	0.671241793363661	ACTR2/ACTR3/NUP62/KPNB1/CHMP1B	5
GO:0001976	nervous system process involved in regulation of systemic arterial blood pressure	1/1068	12/18722	0.505919268645295	0.671241793363661	SOD2	1
GO:0002024	diet induced thermogenesis	1/1068	12/18722	0.505919268645295	0.671241793363661	SORL1	1
GO:0002328	pro-B cell differentiation	1/1068	12/18722	0.505919268645295	0.671241793363661	FNIP1	1
GO:0003207	cardiac chamber formation	1/1068	12/18722	0.505919268645295	0.671241793363661	MEF2C	1
GO:0006068	ethanol catabolic process	1/1068	12/18722	0.505919268645295	0.671241793363661	ALDH2	1
GO:0006285	base-excision repair, AP site formation	1/1068	12/18722	0.505919268645295	0.671241793363661	MBD4	1
GO:0006563	L-serine metabolic process	1/1068	12/18722	0.505919268645295	0.671241793363661	SDS	1
GO:0006703	estrogen biosynthetic process	1/1068	12/18722	0.505919268645295	0.671241793363661	HSD17B11	1
GO:0009886	post-embryonic animal morphogenesis	1/1068	12/18722	0.505919268645295	0.671241793363661	BAX	1
GO:0010623	programmed cell death involved in cell development	1/1068	12/18722	0.505919268645295	0.671241793363661	BAX	1
GO:0014831	gastro-intestinal system smooth muscle contraction	1/1068	12/18722	0.505919268645295	0.671241793363661	PTAFR	1
GO:0014889	muscle atrophy	1/1068	12/18722	0.505919268645295	0.671241793363661	GSN	1
GO:0016188	synaptic vesicle maturation	1/1068	12/18722	0.505919268645295	0.671241793363661	PICALM	1
GO:0019627	urea metabolic process	1/1068	12/18722	0.505919268645295	0.671241793363661	CEBPA	1
GO:0021670	lateral ventricle development	1/1068	12/18722	0.505919268645295	0.671241793363661	NUMB	1
GO:0031223	auditory behavior	1/1068	12/18722	0.505919268645295	0.671241793363661	SLC1A3	1
GO:0032306	regulation of prostaglandin secretion	1/1068	12/18722	0.505919268645295	0.671241793363661	IL1B	1
GO:0032536	regulation of cell projection size	1/1068	12/18722	0.505919268645295	0.671241793363661	TWF2	1
GO:0032926	negative regulation of activin receptor signaling pathway	1/1068	12/18722	0.505919268645295	0.671241793363661	SKI	1
GO:0033079	immature T cell proliferation	1/1068	12/18722	0.505919268645295	0.671241793363661	IL1B	1
GO:0033127	regulation of histone phosphorylation	1/1068	12/18722	0.505919268645295	0.671241793363661	IL1B	1
GO:0033235	positive regulation of protein sumoylation	1/1068	12/18722	0.505919268645295	0.671241793363661	PIAS1	1
GO:0033523	histone H2B ubiquitination	1/1068	12/18722	0.505919268645295	0.671241793363661	DTX3L	1
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	1/1068	12/18722	0.505919268645295	0.671241793363661	SCP2	1
GO:0033629	negative regulation of cell adhesion mediated by integrin	1/1068	12/18722	0.505919268645295	0.671241793363661	WNK1	1
GO:0034086	maintenance of sister chromatid cohesion	1/1068	12/18722	0.505919268645295	0.671241793363661	RB1	1
GO:0034088	maintenance of mitotic sister chromatid cohesion	1/1068	12/18722	0.505919268645295	0.671241793363661	RB1	1
GO:0034392	negative regulation of smooth muscle cell apoptotic process	1/1068	12/18722	0.505919268645295	0.671241793363661	ARRB2	1
GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	1/1068	12/18722	0.505919268645295	0.671241793363661	SYK	1
GO:0042118	endothelial cell activation	1/1068	12/18722	0.505919268645295	0.671241793363661	TGFBR1	1
GO:0042762	regulation of sulfur metabolic process	1/1068	12/18722	0.505919268645295	0.671241793363661	PDK4	1
GO:0043471	regulation of cellular carbohydrate catabolic process	1/1068	12/18722	0.505919268645295	0.671241793363661	SCARB2	1
GO:0044650	adhesion of symbiont to host cell	1/1068	12/18722	0.505919268645295	0.671241793363661	CD81	1
GO:0045117	azole transmembrane transport	1/1068	12/18722	0.505919268645295	0.671241793363661	SLC25A19	1
GO:0045602	negative regulation of endothelial cell differentiation	1/1068	12/18722	0.505919268645295	0.671241793363661	VEGFA	1
GO:0046185	aldehyde catabolic process	1/1068	12/18722	0.505919268645295	0.671241793363661	AKR1A1	1
GO:0048934	peripheral nervous system neuron differentiation	1/1068	12/18722	0.505919268645295	0.671241793363661	RUNX1	1
GO:0048935	peripheral nervous system neuron development	1/1068	12/18722	0.505919268645295	0.671241793363661	RUNX1	1
GO:0051095	regulation of helicase activity	1/1068	12/18722	0.505919268645295	0.671241793363661	IFIT1	1
GO:0051340	regulation of ligase activity	1/1068	12/18722	0.505919268645295	0.671241793363661	TMSB4X	1
GO:0060123	regulation of growth hormone secretion	1/1068	12/18722	0.505919268645295	0.671241793363661	SERP1	1
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	1/1068	12/18722	0.505919268645295	0.671241793363661	LRP1	1
GO:0060453	regulation of gastric acid secretion	1/1068	12/18722	0.505919268645295	0.671241793363661	SGK1	1
GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	1/1068	12/18722	0.505919268645295	0.671241793363661	PRKACB	1
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	1/1068	12/18722	0.505919268645295	0.671241793363661	HAMP	1
GO:0061430	bone trabecula morphogenesis	1/1068	12/18722	0.505919268645295	0.671241793363661	MMP2	1
GO:0061620	glycolytic process through glucose-6-phosphate	1/1068	12/18722	0.505919268645295	0.671241793363661	ADPGK	1
GO:0070213	protein auto-ADP-ribosylation	1/1068	12/18722	0.505919268645295	0.671241793363661	PARP12	1
GO:0070493	thrombin-activated receptor signaling pathway	1/1068	12/18722	0.505919268645295	0.671241793363661	PLEK	1
GO:0071107	response to parathyroid hormone	1/1068	12/18722	0.505919268645295	0.671241793363661	MEF2C	1
GO:0071287	cellular response to manganese ion	1/1068	12/18722	0.505919268645295	0.671241793363661	LRRK2	1
GO:0071712	ER-associated misfolded protein catabolic process	1/1068	12/18722	0.505919268645295	0.671241793363661	SDF2L1	1
GO:0071941	nitrogen cycle metabolic process	1/1068	12/18722	0.505919268645295	0.671241793363661	CEBPA	1
GO:0072182	regulation of nephron tubule epithelial cell differentiation	1/1068	12/18722	0.505919268645295	0.671241793363661	STAT1	1
GO:0072376	protein activation cascade	1/1068	12/18722	0.505919268645295	0.671241793363661	PRCP	1
GO:0072683	T cell extravasation	1/1068	12/18722	0.505919268645295	0.671241793363661	ITGAL	1
GO:0090557	establishment of endothelial intestinal barrier	1/1068	12/18722	0.505919268645295	0.671241793363661	MYD88	1
GO:0090677	reversible differentiation	1/1068	12/18722	0.505919268645295	0.671241793363661	SOD2	1
GO:0099151	regulation of postsynaptic density assembly	1/1068	12/18722	0.505919268645295	0.671241793363661	ABI3	1
GO:1901298	regulation of hydrogen peroxide-mediated programmed cell death	1/1068	12/18722	0.505919268645295	0.671241793363661	HGF	1
GO:1901894	regulation of ATPase-coupled calcium transmembrane transporter activity	1/1068	12/18722	0.505919268645295	0.671241793363661	VMP1	1
GO:1903332	regulation of protein folding	1/1068	12/18722	0.505919268645295	0.671241793363661	GRN	1
GO:1903599	positive regulation of autophagy of mitochondrion	1/1068	12/18722	0.505919268645295	0.671241793363661	HIF1A	1
GO:1903624	regulation of DNA catabolic process	1/1068	12/18722	0.505919268645295	0.671241793363661	BAX	1
GO:1905205	positive regulation of connective tissue replacement	1/1068	12/18722	0.505919268645295	0.671241793363661	ROCK1	1
GO:1905709	negative regulation of membrane permeability	1/1068	12/18722	0.505919268645295	0.671241793363661	ACAA2	1
GO:1990034	calcium ion export across plasma membrane	1/1068	12/18722	0.505919268645295	0.671241793363661	CALM3	1
GO:2000035	regulation of stem cell division	1/1068	12/18722	0.505919268645295	0.671241793363661	EVI2B	1
GO:0030111	regulation of Wnt signaling pathway	19/1068	328/18722	0.506461016061015	0.671795389052418	APOE/ZEB2/RNF213/TLR2/ATP6AP2/TGFB1/MDFIC/LRRK2/STK4/TNFAIP3/LRP1/TLE3/APC/SKI/PFDN5/GNAQ/XIAP/WNK1/EGR1	19
GO:0001754	eye photoreceptor cell differentiation	3/1068	47/18722	0.506865032397922	0.672000912731986	VEGFA/PRDM1/STAT3	3
GO:0047496	vesicle transport along microtubule	3/1068	47/18722	0.506865032397922	0.672000912731986	BLOC1S1/BLOC1S2/KIF5B	3
GO:0006487	protein N-linked glycosylation	4/1068	65/18722	0.512081522944291	0.678416866635746	MGAT4A/MGAT1/SRD5A3/KRTCAP2	4
GO:0035418	protein localization to synapse	4/1068	65/18722	0.512081522944291	0.678416866635746	RAP1A/ADAM10/RAB8A/KIF5B	4
GO:0061512	protein localization to cilium	4/1068	65/18722	0.512081522944291	0.678416866635746	SNX10/CCDC88A/GGA1/RAB29	4
GO:0006936	muscle contraction	20/1068	347/18722	0.514150553936657	0.680990768051596	CXCR4/SLC8A1/DOCK4/FLNA/TPM3/RHOA/PTAFR/KCNE3/RCSD1/ATP1B1/VEGFB/CALM3/ROCK1/GSTO1/GSN/NR4A1/GAA/RGS2/MYL6/ATP1A1	20
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	2/1068	30/18722	0.516900437786899	0.682455288059238	DNASE2/BAX	2
GO:0015865	purine nucleotide transport	2/1068	30/18722	0.516900437786899	0.682455288059238	SLC25A24/LRRC8C	2
GO:0017145	stem cell division	2/1068	30/18722	0.516900437786899	0.682455288059238	ZFP36L2/EVI2B	2
GO:0030204	chondroitin sulfate metabolic process	2/1068	30/18722	0.516900437786899	0.682455288059238	DSE/CSGALNACT2	2
GO:0034694	response to prostaglandin	2/1068	30/18722	0.516900437786899	0.682455288059238	PTGER4/GNB1	2
GO:0036258	multivesicular body assembly	2/1068	30/18722	0.516900437786899	0.682455288059238	CHMP3/CHMP1B	2
GO:0045939	negative regulation of steroid metabolic process	2/1068	30/18722	0.516900437786899	0.682455288059238	APOE/ATP1A1	2
GO:0048799	animal organ maturation	2/1068	30/18722	0.516900437786899	0.682455288059238	SNX10/RHOA	2
GO:0051968	positive regulation of synaptic transmission, glutamatergic	2/1068	30/18722	0.516900437786899	0.682455288059238	GLUL/PTK2B	2
GO:0060292	long-term synaptic depression	2/1068	30/18722	0.516900437786899	0.682455288059238	LILRB2/PTK2B	2
GO:0061311	cell surface receptor signaling pathway involved in heart development	2/1068	30/18722	0.516900437786899	0.682455288059238	TGFB1/NOTCH2	2
GO:0061384	heart trabecula morphogenesis	2/1068	30/18722	0.516900437786899	0.682455288059238	ENG/TGFBR1	2
GO:1903019	negative regulation of glycoprotein metabolic process	2/1068	30/18722	0.516900437786899	0.682455288059238	CST3/HBEGF	2
GO:0051168	nuclear export	9/1068	154/18722	0.519222463059997	0.685353329420681	IFI27/NUP214/SP100/ATXN1/TGFB1/IL1B/NUP62/UHMK1/AKAP13	9
GO:0045787	positive regulation of cell cycle	18/1068	313/18722	0.520771735544037	0.687230199314166	AIF1/NUPR1/LGMN/RB1/PLSCR1/RHOA/EIF4EBP1/KMT2E/IL1B/RGCC/DUSP3/ADAM17/NUP62/CCPG1/DYNC1LI1/CDC42/CHMP3/RCC2	18
GO:0051216	cartilage development	11/1068	190/18722	0.524192445229785	0.690595874059759	TIMP1/CD44/TGFBI/HIF1A/MEF2C/MAF/TGFB1/TGFBR2/TRPS1/RUNX1/TGFBR1	11
GO:0006303	double-strand break repair via nonhomologous end joining	4/1068	66/18722	0.524226400800795	0.690595874059759	PARP9/DTX3L/ERCC1/ATM	4
GO:0050922	negative regulation of chemotaxis	4/1068	66/18722	0.524226400800795	0.690595874059759	AIF1/DUSP1/RIN3/DUSP3	4
GO:0007586	digestion	8/1068	137/18722	0.524788978270411	0.690595874059759	TYMP/HAMP/SGK1/SNX10/CD36/TLR4/NR1H3/WNK1	8
GO:0034308	primary alcohol metabolic process	6/1068	102/18722	0.529096487115408	0.690595874059759	ALDH2/ALDH1A1/RDH11/AKR1A1/DHRS3/DHRS4	6
GO:0071774	response to fibroblast growth factor	7/1068	120/18722	0.531195252683968	0.690595874059759	CD44/ZFP36L2/ZFP36/ZFP36L1/SETX/NR4A1/IER2	7
GO:0001778	plasma membrane repair	1/1068	13/18722	0.534122273513645	0.690595874059759	ARL8B	1
GO:0003334	keratinocyte development	1/1068	13/18722	0.534122273513645	0.690595874059759	PLEC	1
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	1/1068	13/18722	0.534122273513645	0.690595874059759	STAT1	1
GO:0005513	detection of calcium ion	1/1068	13/18722	0.534122273513645	0.690595874059759	CALM3	1
GO:0006000	fructose metabolic process	1/1068	13/18722	0.534122273513645	0.690595874059759	FBP1	1
GO:0006995	cellular response to nitrogen starvation	1/1068	13/18722	0.534122273513645	0.690595874059759	GABARAP	1
GO:0007183	SMAD protein complex assembly	1/1068	13/18722	0.534122273513645	0.690595874059759	TGFB1	1
GO:0007567	parturition	1/1068	13/18722	0.534122273513645	0.690595874059759	PTAFR	1
GO:0009134	nucleoside diphosphate catabolic process	1/1068	13/18722	0.534122273513645	0.690595874059759	ENTPD1	1
GO:0009143	nucleoside triphosphate catabolic process	1/1068	13/18722	0.534122273513645	0.690595874059759	SAMHD1	1
GO:0009437	carnitine metabolic process	1/1068	13/18722	0.534122273513645	0.690595874059759	CPT1A	1
GO:0010635	regulation of mitochondrial fusion	1/1068	13/18722	0.534122273513645	0.690595874059759	VAT1	1
GO:0010958	regulation of amino acid import across plasma membrane	1/1068	13/18722	0.534122273513645	0.690595874059759	RGS2	1
GO:0014745	negative regulation of muscle adaptation	1/1068	13/18722	0.534122273513645	0.690595874059759	KLF4	1
GO:0015791	polyol transport	1/1068	13/18722	0.534122273513645	0.690595874059759	AQP9	1
GO:0015809	arginine transport	1/1068	13/18722	0.534122273513645	0.690595874059759	SLC11A1	1
GO:0015816	glycine transport	1/1068	13/18722	0.534122273513645	0.690595874059759	RGS2	1
GO:0016024	CDP-diacylglycerol biosynthetic process	1/1068	13/18722	0.534122273513645	0.690595874059759	AGPAT2	1
GO:0016246	RNA interference	1/1068	13/18722	0.534122273513645	0.690595874059759	ADAR	1
GO:0019336	phenol-containing compound catabolic process	1/1068	13/18722	0.534122273513645	0.690595874059759	FAH	1
GO:0019755	one-carbon compound transport	1/1068	13/18722	0.534122273513645	0.690595874059759	AQP9	1
GO:0021554	optic nerve development	1/1068	13/18722	0.534122273513645	0.690595874059759	TCIRG1	1
GO:0021859	pyramidal neuron differentiation	1/1068	13/18722	0.534122273513645	0.690595874059759	ZMIZ1	1
GO:0030497	fatty acid elongation	1/1068	13/18722	0.534122273513645	0.690595874059759	HACD4	1
GO:0030836	positive regulation of actin filament depolymerization	1/1068	13/18722	0.534122273513645	0.690595874059759	PLEK	1
GO:0031053	primary miRNA processing	1/1068	13/18722	0.534122273513645	0.690595874059759	STAT3	1
GO:0032230	positive regulation of synaptic transmission, GABAergic	1/1068	13/18722	0.534122273513645	0.690595874059759	KIF5B	1
GO:0032530	regulation of microvillus organization	1/1068	13/18722	0.534122273513645	0.690595874059759	TWF2	1
GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway	1/1068	13/18722	0.534122273513645	0.690595874059759	PAK1	1
GO:0033262	regulation of nuclear cell cycle DNA replication	1/1068	13/18722	0.534122273513645	0.690595874059759	BCL6	1
GO:0033689	negative regulation of osteoblast proliferation	1/1068	13/18722	0.534122273513645	0.690595874059759	EIF2AK2	1
GO:0034982	mitochondrial protein processing	1/1068	13/18722	0.534122273513645	0.690595874059759	LRRK2	1
GO:0036302	atrioventricular canal development	1/1068	13/18722	0.534122273513645	0.690595874059759	ENG	1
GO:0042538	hyperosmotic salinity response	1/1068	13/18722	0.534122273513645	0.690595874059759	MICU1	1
GO:0042761	very long-chain fatty acid biosynthetic process	1/1068	13/18722	0.534122273513645	0.690595874059759	HACD4	1
GO:0043247	telomere maintenance in response to DNA damage	1/1068	13/18722	0.534122273513645	0.690595874059759	ERCC1	1
GO:0043562	cellular response to nitrogen levels	1/1068	13/18722	0.534122273513645	0.690595874059759	GABARAP	1
GO:0044090	positive regulation of vacuole organization	1/1068	13/18722	0.534122273513645	0.690595874059759	GRN	1
GO:0048207	vesicle targeting, rough ER to cis-Golgi	1/1068	13/18722	0.534122273513645	0.690595874059759	TMED10	1
GO:0048208	COPII vesicle coating	1/1068	13/18722	0.534122273513645	0.690595874059759	TMED10	1
GO:0048266	behavioral response to pain	1/1068	13/18722	0.534122273513645	0.690595874059759	TSPO	1
GO:0048302	regulation of isotype switching to IgG isotypes	1/1068	13/18722	0.534122273513645	0.690595874059759	PTPRC	1
GO:0048711	positive regulation of astrocyte differentiation	1/1068	13/18722	0.534122273513645	0.690595874059759	ID2	1
GO:0051956	negative regulation of amino acid transport	1/1068	13/18722	0.534122273513645	0.690595874059759	RGS2	1
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	1/1068	13/18722	0.534122273513645	0.690595874059759	IRF7	1
GO:0061000	negative regulation of dendritic spine development	1/1068	13/18722	0.534122273513645	0.690595874059759	UBE3A	1
GO:0061615	glycolytic process through fructose-6-phosphate	1/1068	13/18722	0.534122273513645	0.690595874059759	ADPGK	1
GO:0070254	mucus secretion	1/1068	13/18722	0.534122273513645	0.690595874059759	CYBA	1
GO:0070914	UV-damage excision repair	1/1068	13/18722	0.534122273513645	0.690595874059759	ERCC1	1
GO:0072578	neurotransmitter-gated ion channel clustering	1/1068	13/18722	0.534122273513645	0.690595874059759	APOE	1
GO:0090042	tubulin deacetylation	1/1068	13/18722	0.534122273513645	0.690595874059759	FLNA	1
GO:0090158	endoplasmic reticulum membrane organization	1/1068	13/18722	0.534122273513645	0.690595874059759	RTN4	1
GO:0098840	protein transport along microtubule	1/1068	13/18722	0.534122273513645	0.690595874059759	KIF5B	1
GO:0099118	microtubule-based protein transport	1/1068	13/18722	0.534122273513645	0.690595874059759	KIF5B	1
GO:0099150	regulation of postsynaptic specialization assembly	1/1068	13/18722	0.534122273513645	0.690595874059759	ABI3	1
GO:0106070	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	1/1068	13/18722	0.534122273513645	0.690595874059759	GNAI2	1
GO:1900121	negative regulation of receptor binding	1/1068	13/18722	0.534122273513645	0.690595874059759	B2M	1
GO:1900452	regulation of long-term synaptic depression	1/1068	13/18722	0.534122273513645	0.690595874059759	LILRB2	1
GO:1901387	positive regulation of voltage-gated calcium channel activity	1/1068	13/18722	0.534122273513645	0.690595874059759	KCNE3	1
GO:1902260	negative regulation of delayed rectifier potassium channel activity	1/1068	13/18722	0.534122273513645	0.690595874059759	KCNE3	1
GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	1/1068	13/18722	0.534122273513645	0.690595874059759	TMSB4X	1
GO:1903789	regulation of amino acid transmembrane transport	1/1068	13/18722	0.534122273513645	0.690595874059759	RGS2	1
GO:1904478	regulation of intestinal absorption	1/1068	13/18722	0.534122273513645	0.690595874059759	HAMP	1
GO:1904925	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	1/1068	13/18722	0.534122273513645	0.690595874059759	VPS13C	1
GO:1904995	negative regulation of leukocyte adhesion to vascular endothelial cell	1/1068	13/18722	0.534122273513645	0.690595874059759	KLF4	1
GO:0030201	heparan sulfate proteoglycan metabolic process	2/1068	31/18722	0.534690905202038	0.690595874059759	DSE/HPSE	2
GO:0035510	DNA dealkylation	2/1068	31/18722	0.534690905202038	0.690595874059759	APOBEC3C/APOBEC3A	2
GO:0036257	multivesicular body organization	2/1068	31/18722	0.534690905202038	0.690595874059759	CHMP3/CHMP1B	2
GO:0036474	cell death in response to hydrogen peroxide	2/1068	31/18722	0.534690905202038	0.690595874059759	HGF/LRRK2	2
GO:0042133	neurotransmitter metabolic process	2/1068	31/18722	0.534690905202038	0.690595874059759	GCHFR/HNMT	2
GO:0045987	positive regulation of smooth muscle contraction	2/1068	31/18722	0.534690905202038	0.690595874059759	RHOA/PTAFR	2
GO:0048384	retinoic acid receptor signaling pathway	2/1068	31/18722	0.534690905202038	0.690595874059759	KLF2/DHRS3	2
GO:0048710	regulation of astrocyte differentiation	2/1068	31/18722	0.534690905202038	0.690595874059759	TREM2/ID2	2
GO:0061099	negative regulation of protein tyrosine kinase activity	2/1068	31/18722	0.534690905202038	0.690595874059759	LILRB4/PTPRC	2
GO:0070633	transepithelial transport	2/1068	31/18722	0.534690905202038	0.690595874059759	ACTB/SLC1A3	2
GO:0071168	protein localization to chromatin	2/1068	31/18722	0.534690905202038	0.690595874059759	SPI1/RB1	2
GO:0090183	regulation of kidney development	2/1068	31/18722	0.534690905202038	0.690595874059759	STAT1/VEGFA	2
GO:0007411	axon guidance	13/1068	227/18722	0.535013540924536	0.690595874059759	ALCAM/PLXNC1/DPYSL2/RHOG/VEGFA/PLXND1/NOTCH2/VASP/CYFIP1/RAC1/LRP1/KIF5B/B3GNT2	13
GO:0008206	bile acid metabolic process	3/1068	49/18722	0.535224600689013	0.690595874059759	CYP27A1/OSBPL1A/SCP2	3
GO:0030857	negative regulation of epithelial cell differentiation	3/1068	49/18722	0.535224600689013	0.690595874059759	STAT1/VEGFA/SPRED1	3
GO:0035088	establishment or maintenance of apical/basal cell polarity	3/1068	49/18722	0.535224600689013	0.690595874059759	MSN/RHOA/CDC42	3
GO:0038084	vascular endothelial growth factor signaling pathway	3/1068	49/18722	0.535224600689013	0.690595874059759	CD63/VEGFA/VEGFB	3
GO:0048168	regulation of neuronal synaptic plasticity	3/1068	49/18722	0.535224600689013	0.690595874059759	APOE/MCTP1/RAB8A	3
GO:0051445	regulation of meiotic cell cycle	3/1068	49/18722	0.535224600689013	0.690595874059759	DUSP1/PRKAR1A/PRKACB	3
GO:0060986	endocrine hormone secretion	3/1068	49/18722	0.535224600689013	0.690595874059759	RETN/RAB8B/IL1B	3
GO:0061245	establishment or maintenance of bipolar cell polarity	3/1068	49/18722	0.535224600689013	0.690595874059759	MSN/RHOA/CDC42	3
GO:0072091	regulation of stem cell proliferation	3/1068	49/18722	0.535224600689013	0.690595874059759	ZFP36L1/PTPRC/EIF2AK2	3
GO:0032890	regulation of organic acid transport	4/1068	67/18722	0.536223968818069	0.69171994638831	SYK/ACSL1/IL1B/RGS2	4
GO:0060021	roof of mouth development	5/1068	85/18722	0.537440431511497	0.6929578419202	TGFBR2/SGPL1/DHRS3/TGFBR1/SKI	5
GO:0097194	execution phase of apoptosis	5/1068	85/18722	0.537440431511497	0.6929578419202	DNASE2/PLSCR1/PAK2/TAOK1/BAX	5
GO:0019233	sensory perception of pain	6/1068	103/18722	0.538751423495662	0.694482245863018	FABP5/CCL3/CXCR4/ARRB2/P2RX7/PTAFR	6
GO:0097485	neuron projection guidance	13/1068	228/18722	0.541508261092635	0.697869256473814	ALCAM/PLXNC1/DPYSL2/RHOG/VEGFA/PLXND1/NOTCH2/VASP/CYFIP1/RAC1/LRP1/KIF5B/B3GNT2	13
GO:0007030	Golgi organization	9/1068	157/18722	0.542795905478661	0.69936167764156	VMP1/PLK3/LRRK2/STX6/RAB29/ATL3/TMED5/TMED10/CDC42	9
GO:0003007	heart morphogenesis	14/1068	246/18722	0.542984492236501	0.699437651016509	HIF1A/MEF2C/FLNA/ZMIZ1/VEGFA/PLXND1/TGFB1/ENG/TGFBR2/NOTCH2/DHRS3/TGFBR1/RTN4/GAA	14
GO:0046474	glycerophospholipid biosynthetic process	12/1068	211/18722	0.546713060506621	0.704072476012822	FABP5/PLSCR1/LPCAT2/AGPAT2/INPP5D/SOCS3/MTMR6/EFR3A/ATM/CEPT1/PIK3R1/SOCS6	12
GO:0001654	eye development	21/1068	371/18722	0.547105761725059	0.704410090734531	VIM/SKIL/HIF1A/KLF4/VEGFA/MAF/TGFBR2/TCIRG1/PRDM1/PBX3/NOTCH2/MITF/SPRED1/SCO2/STAT3/TGFBR1/GNB1/MAX/SKI/PFDN5/BAX	21
GO:2001251	negative regulation of chromosome organization	5/1068	86/18722	0.54796613459941	0.705311839137923	DUSP1/ERCC1/ATM/APC/DYNC1LI1	5
GO:1901607	alpha-amino acid biosynthetic process	4/1068	68/18722	0.54806755772893	0.705311839137923	GLUL/SDS/SDSL/GLS	4
GO:0031109	microtubule polymerization or depolymerization	7/1068	122/18722	0.548931477177526	0.7057371365875	CIB1/HSPA1A/ARHGEF2/RAC1/APC/PAK1/TAOK1	7
GO:0007080	mitotic metaphase plate congression	3/1068	50/18722	0.549051982838088	0.7057371365875	NUP62/KPNB1/CHMP1B	3
GO:0051646	mitochondrion localization	3/1068	50/18722	0.549051982838088	0.7057371365875	MEF2A/HIF1A/LRRK2	3
GO:1903747	regulation of establishment of protein localization to mitochondrion	3/1068	50/18722	0.549051982838088	0.7057371365875	LRRK2/BNIP3L/UBE2D3	3
GO:1904036	negative regulation of epithelial cell apoptotic process	3/1068	50/18722	0.549051982838088	0.7057371365875	NUPR1/HMOX1/TNFAIP3	3
GO:0006308	DNA catabolic process	2/1068	32/18722	0.552025926752421	0.708041811446652	DNASE2/BAX	2
GO:0010667	negative regulation of cardiac muscle cell apoptotic process	2/1068	32/18722	0.552025926752421	0.708041811446652	NUPR1/JAK2	2
GO:0014044	Schwann cell development	2/1068	32/18722	0.552025926752421	0.708041811446652	SKI/PLEC	2
GO:0021799	cerebral cortex radially oriented cell migration	2/1068	32/18722	0.552025926752421	0.708041811446652	ZMIZ1/RTN4	2
GO:0030431	sleep	2/1068	32/18722	0.552025926752421	0.708041811446652	FOS/IL18	2
GO:0032196	transposition	2/1068	32/18722	0.552025926752421	0.708041811446652	APOBEC3C/APOBEC3A	2
GO:0045879	negative regulation of smoothened signaling pathway	2/1068	32/18722	0.552025926752421	0.708041811446652	RB1/PRKACB	2
GO:0046856	phosphatidylinositol dephosphorylation	2/1068	32/18722	0.552025926752421	0.708041811446652	INPP5D/MTMR6	2
GO:0051642	centrosome localization	2/1068	32/18722	0.552025926752421	0.708041811446652	RANBP2/KIF5B	2
GO:0016055	Wnt signaling pathway	25/1068	444/18722	0.556810068690672	0.710241308154827	APOE/ZEB2/RNF213/RHOA/TLR2/NR4A2/ATP6AP2/KLF4/TGFB1/MDFIC/MITF/LRRK2/STK4/RAC1/TNFAIP3/LRP1/TLE3/APC/SKI/PFDN5/GNAQ/CDC42/XIAP/WNK1/EGR1	25
GO:0051966	regulation of synaptic transmission, glutamatergic	4/1068	69/18722	0.559751051941811	0.710241308154827	GLUL/MEF2C/LRRK2/PTK2B	4
GO:0003214	cardiac left ventricle morphogenesis	1/1068	14/18722	0.560716822227495	0.710241308154827	TGFBR2	1
GO:0003376	sphingosine-1-phosphate receptor signaling pathway	1/1068	14/18722	0.560716822227495	0.710241308154827	RAC1	1
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	1/1068	14/18722	0.560716822227495	0.710241308154827	TGFBR2	1
GO:0006521	regulation of cellular amino acid metabolic process	1/1068	14/18722	0.560716822227495	0.710241308154827	SLC7A7	1
GO:0006999	nuclear pore organization	1/1068	14/18722	0.560716822227495	0.710241308154827	RTN4	1
GO:0007100	mitotic centrosome separation	1/1068	14/18722	0.560716822227495	0.710241308154827	NUP62	1
GO:0007638	mechanosensory behavior	1/1068	14/18722	0.560716822227495	0.710241308154827	SLC1A3	1
GO:0009071	serine family amino acid catabolic process	1/1068	14/18722	0.560716822227495	0.710241308154827	SDS	1
GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	1/1068	14/18722	0.560716822227495	0.710241308154827	UPP1	1
GO:0010421	hydrogen peroxide-mediated programmed cell death	1/1068	14/18722	0.560716822227495	0.710241308154827	HGF	1
GO:0010838	positive regulation of keratinocyte proliferation	1/1068	14/18722	0.560716822227495	0.710241308154827	NOTCH2	1
GO:0010867	positive regulation of triglyceride biosynthetic process	1/1068	14/18722	0.560716822227495	0.710241308154827	NR1H3	1
GO:0010896	regulation of triglyceride catabolic process	1/1068	14/18722	0.560716822227495	0.710241308154827	SORL1	1
GO:0010989	negative regulation of low-density lipoprotein particle clearance	1/1068	14/18722	0.560716822227495	0.710241308154827	CSK	1
GO:0015812	gamma-aminobutyric acid transport	1/1068	14/18722	0.560716822227495	0.710241308154827	SLC6A6	1
GO:0018158	protein oxidation	1/1068	14/18722	0.560716822227495	0.710241308154827	GPX1	1
GO:0030049	muscle filament sliding	1/1068	14/18722	0.560716822227495	0.710241308154827	MYL6	1
GO:0031054	pre-miRNA processing	1/1068	14/18722	0.560716822227495	0.710241308154827	ADAR	1
GO:0031650	regulation of heat generation	1/1068	14/18722	0.560716822227495	0.710241308154827	IL1B	1
GO:0033169	histone H3-K9 demethylation	1/1068	14/18722	0.560716822227495	0.710241308154827	JMJD1C	1
GO:0035630	bone mineralization involved in bone maturation	1/1068	14/18722	0.560716822227495	0.710241308154827	SNX10	1
GO:0035672	oligopeptide transmembrane transport	1/1068	14/18722	0.560716822227495	0.710241308154827	SLC15A3	1
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	1/1068	14/18722	0.560716822227495	0.710241308154827	LRP1	1
GO:0035810	positive regulation of urine volume	1/1068	14/18722	0.560716822227495	0.710241308154827	GNAI2	1
GO:0035815	positive regulation of renal sodium excretion	1/1068	14/18722	0.560716822227495	0.710241308154827	GNAI2	1
GO:0036444	calcium import into the mitochondrion	1/1068	14/18722	0.560716822227495	0.710241308154827	MICU1	1
GO:0043951	negative regulation of cAMP-mediated signaling	1/1068	14/18722	0.560716822227495	0.710241308154827	RGS2	1
GO:0044764	multi-organism cellular process	1/1068	14/18722	0.560716822227495	0.710241308154827	SIGLEC1	1
GO:0045472	response to ether	1/1068	14/18722	0.560716822227495	0.710241308154827	PTAFR	1
GO:0046325	negative regulation of glucose import	1/1068	14/18722	0.560716822227495	0.710241308154827	PEA15	1
GO:0046341	CDP-diacylglycerol metabolic process	1/1068	14/18722	0.560716822227495	0.710241308154827	AGPAT2	1
GO:0046462	monoacylglycerol metabolic process	1/1068	14/18722	0.560716822227495	0.710241308154827	ABHD12	1
GO:0046655	folic acid metabolic process	1/1068	14/18722	0.560716822227495	0.710241308154827	MTHFD2	1
GO:0048291	isotype switching to IgG isotypes	1/1068	14/18722	0.560716822227495	0.710241308154827	PTPRC	1
GO:0048681	negative regulation of axon regeneration	1/1068	14/18722	0.560716822227495	0.710241308154827	SPP1	1
GO:0050872	white fat cell differentiation	1/1068	14/18722	0.560716822227495	0.710241308154827	CEBPA	1
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	1/1068	14/18722	0.560716822227495	0.710241308154827	CXCR4	1
GO:0051645	Golgi localization	1/1068	14/18722	0.560716822227495	0.710241308154827	CDC42	1
GO:0051984	positive regulation of chromosome segregation	1/1068	14/18722	0.560716822227495	0.710241308154827	RCC2	1
GO:0060732	positive regulation of inositol phosphate biosynthetic process	1/1068	14/18722	0.560716822227495	0.710241308154827	PTAFR	1
GO:0070307	lens fiber cell development	1/1068	14/18722	0.560716822227495	0.710241308154827	VIM	1
GO:0070986	left/right axis specification	1/1068	14/18722	0.560716822227495	0.710241308154827	NOTCH2	1
GO:0090239	regulation of histone H4 acetylation	1/1068	14/18722	0.560716822227495	0.710241308154827	SPI1	1
GO:0090281	negative regulation of calcium ion import	1/1068	14/18722	0.560716822227495	0.710241308154827	SLC30A1	1
GO:1900037	regulation of cellular response to hypoxia	1/1068	14/18722	0.560716822227495	0.710241308154827	TMBIM6	1
GO:1902036	regulation of hematopoietic stem cell differentiation	1/1068	14/18722	0.560716822227495	0.710241308154827	EIF2AK2	1
GO:1902187	negative regulation of viral release from host cell	1/1068	14/18722	0.560716822227495	0.710241308154827	CHMP3	1
GO:1902969	mitotic DNA replication	1/1068	14/18722	0.560716822227495	0.710241308154827	BCL6	1
GO:1903894	regulation of IRE1-mediated unfolded protein response	1/1068	14/18722	0.560716822227495	0.710241308154827	BAX	1
GO:1904294	positive regulation of ERAD pathway	1/1068	14/18722	0.560716822227495	0.710241308154827	HERPUD1	1
GO:1904923	regulation of autophagy of mitochondrion in response to mitochondrial depolarization	1/1068	14/18722	0.560716822227495	0.710241308154827	VPS13C	1
GO:0045104	intermediate filament cytoskeleton organization	3/1068	51/18722	0.562633968202693	0.712168166179153	VIM/KLHL24/PLEC	3
GO:0048013	ephrin receptor signaling pathway	3/1068	51/18722	0.562633968202693	0.712168166179153	LYN/MMP2/PAK1	3
GO:0051339	regulation of lyase activity	3/1068	51/18722	0.562633968202693	0.712168166179153	TIMP2/GNAI2/CAP1	3
GO:0198738	cell-cell signaling by wnt	25/1068	446/18722	0.566071882892085	0.716351754241485	APOE/ZEB2/RNF213/RHOA/TLR2/NR4A2/ATP6AP2/KLF4/TGFB1/MDFIC/MITF/LRRK2/STK4/RAC1/TNFAIP3/LRP1/TLE3/APC/SKI/PFDN5/GNAQ/CDC42/XIAP/WNK1/EGR1	25
GO:0090263	positive regulation of canonical Wnt signaling pathway	6/1068	106/18722	0.567183594120118	0.717590310403788	ZEB2/ATP6AP2/TGFB1/LRRK2/XIAP/WNK1	6
GO:0003382	epithelial cell morphogenesis	2/1068	33/18722	0.56889953077342	0.719086874690414	ST14/RILPL2	2
GO:0006536	glutamate metabolic process	2/1068	33/18722	0.56889953077342	0.719086874690414	GLUL/GLS	2
GO:0009648	photoperiodism	2/1068	33/18722	0.56889953077342	0.719086874690414	ID2/BHLHE40	2
GO:1901380	negative regulation of potassium ion transmembrane transport	2/1068	33/18722	0.56889953077342	0.719086874690414	KCNE3/CAB39	2
GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	3/1068	52/18722	0.575963978128367	0.727156079849685	TAPBP/TMED10/ARF3	3
GO:0021545	cranial nerve development	3/1068	52/18722	0.575963978128367	0.727156079849685	MAFB/TCIRG1/SLC1A3	3
GO:0045103	intermediate filament-based process	3/1068	52/18722	0.575963978128367	0.727156079849685	VIM/KLHL24/PLEC	3
GO:0060071	Wnt signaling pathway, planar cell polarity pathway	3/1068	52/18722	0.575963978128367	0.727156079849685	RHOA/RAC1/CDC42	3
GO:0072132	mesenchyme morphogenesis	3/1068	52/18722	0.575963978128367	0.727156079849685	ENG/TGFBR2/TGFBR1	3
GO:0000018	regulation of DNA recombination	6/1068	107/18722	0.576471116277526	0.727156079849685	PTPRC/ACTR2/WAS/TGFB1/BCL6/STAT6	6
GO:0005976	polysaccharide metabolic process	6/1068	107/18722	0.576471116277526	0.727156079849685	TGFB1/AOAH/CSGALNACT2/PRKAG2/GAA/B3GNT2	6
GO:0051052	regulation of DNA metabolic process	20/1068	359/18722	0.576731161043495	0.727156079849685	DUSP1/SPI1/PTPRC/ARRB2/HGF/ACTR2/KLF4/PARP9/WAS/TGFB1/DTX3L/BCL6/PARP4/PTK2B/CDKN1A/STAT6/ERCC1/RGCC/ATM/BAX	20
GO:0003281	ventricular septum development	4/1068	71/18722	0.582615967827949	0.727156079849685	TGFBR2/PRDM1/CNTRL/TGFBR1	4
GO:0033555	multicellular organismal response to stress	4/1068	71/18722	0.582615967827949	0.727156079849685	APOE/TSPO/MEF2C/NR4A2	4
GO:0001662	behavioral fear response	2/1068	34/18722	0.5853079064905	0.727156079849685	APOE/MEF2C	2
GO:0010661	positive regulation of muscle cell apoptotic process	2/1068	34/18722	0.5853079064905	0.727156079849685	SOD2/STK4	2
GO:0035909	aorta morphogenesis	2/1068	34/18722	0.5853079064905	0.727156079849685	ENG/LRP1	2
GO:0048536	spleen development	2/1068	34/18722	0.5853079064905	0.727156079849685	ADAM17/PPP2R3C	2
GO:0000722	telomere maintenance via recombination	1/1068	15/18722	0.58579456617987	0.727156079849685	ERCC1	1
GO:0001325	formation of extrachromosomal circular DNA	1/1068	15/18722	0.58579456617987	0.727156079849685	ERCC1	1
GO:0006098	pentose-phosphate shunt	1/1068	15/18722	0.58579456617987	0.727156079849685	PGLS	1
GO:0006268	DNA unwinding involved in DNA replication	1/1068	15/18722	0.58579456617987	0.727156079849685	RECQL	1
GO:0006704	glucocorticoid biosynthetic process	1/1068	15/18722	0.58579456617987	0.727156079849685	ATP1A1	1
GO:0007216	G protein-coupled glutamate receptor signaling pathway	1/1068	15/18722	0.58579456617987	0.727156079849685	HOMER3	1
GO:0009083	branched-chain amino acid catabolic process	1/1068	15/18722	0.58579456617987	0.727156079849685	ACAT1	1
GO:0010273	detoxification of copper ion	1/1068	15/18722	0.58579456617987	0.727156079849685	MT1X	1
GO:0010752	regulation of cGMP-mediated signaling	1/1068	15/18722	0.58579456617987	0.727156079849685	PTK2B	1
GO:0010832	negative regulation of myotube differentiation	1/1068	15/18722	0.58579456617987	0.727156079849685	BHLHE41	1
GO:0014744	positive regulation of muscle adaptation	1/1068	15/18722	0.58579456617987	0.727156079849685	AIF1	1
GO:0015697	quaternary ammonium group transport	1/1068	15/18722	0.58579456617987	0.727156079849685	SLC25A19	1
GO:0016446	somatic hypermutation of immunoglobulin genes	1/1068	15/18722	0.58579456617987	0.727156079849685	SAMHD1	1
GO:0018146	keratan sulfate biosynthetic process	1/1068	15/18722	0.58579456617987	0.727156079849685	B3GNT2	1
GO:0021542	dentate gyrus development	1/1068	15/18722	0.58579456617987	0.727156079849685	BTG2	1
GO:0030252	growth hormone secretion	1/1068	15/18722	0.58579456617987	0.727156079849685	SERP1	1
GO:0032310	prostaglandin secretion	1/1068	15/18722	0.58579456617987	0.727156079849685	IL1B	1
GO:0032328	alanine transport	1/1068	15/18722	0.58579456617987	0.727156079849685	SLC6A6	1
GO:0033275	actin-myosin filament sliding	1/1068	15/18722	0.58579456617987	0.727156079849685	MYL6	1
GO:0034310	primary alcohol catabolic process	1/1068	15/18722	0.58579456617987	0.727156079849685	ALDH2	1
GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	1/1068	15/18722	0.58579456617987	0.727156079849685	FABP5	1
GO:0035435	phosphate ion transmembrane transport	1/1068	15/18722	0.58579456617987	0.727156079849685	SLC37A2	1
GO:0035493	SNARE complex assembly	1/1068	15/18722	0.58579456617987	0.727156079849685	STX4	1
GO:0036124	histone H3-K9 trimethylation	1/1068	15/18722	0.58579456617987	0.727156079849685	ARID4A	1
GO:0043252	sodium-independent organic anion transport	1/1068	15/18722	0.58579456617987	0.727156079849685	SLCO2B1	1
GO:0043584	nose development	1/1068	15/18722	0.58579456617987	0.727156079849685	SKI	1
GO:0044406	adhesion of symbiont to host	1/1068	15/18722	0.58579456617987	0.727156079849685	CD81	1
GO:0045176	apical protein localization	1/1068	15/18722	0.58579456617987	0.727156079849685	ACTB	1
GO:0045217	cell-cell junction maintenance	1/1068	15/18722	0.58579456617987	0.727156079849685	CSF1R	1
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	1/1068	15/18722	0.58579456617987	0.727156079849685	RB1	1
GO:0046184	aldehyde biosynthetic process	1/1068	15/18722	0.58579456617987	0.727156079849685	PDXK	1
GO:0046321	positive regulation of fatty acid oxidation	1/1068	15/18722	0.58579456617987	0.727156079849685	CPT1A	1
GO:0046500	S-adenosylmethionine metabolic process	1/1068	15/18722	0.58579456617987	0.727156079849685	MAT2A	1
GO:0048308	organelle inheritance	1/1068	15/18722	0.58579456617987	0.727156079849685	PLK3	1
GO:0048313	Golgi inheritance	1/1068	15/18722	0.58579456617987	0.727156079849685	PLK3	1
GO:0048712	negative regulation of astrocyte differentiation	1/1068	15/18722	0.58579456617987	0.727156079849685	TREM2	1
GO:0051299	centrosome separation	1/1068	15/18722	0.58579456617987	0.727156079849685	NUP62	1
GO:0051791	medium-chain fatty acid metabolic process	1/1068	15/18722	0.58579456617987	0.727156079849685	ABHD2	1
GO:0051938	L-glutamate import	1/1068	15/18722	0.58579456617987	0.727156079849685	SLC1A3	1
GO:0060413	atrial septum morphogenesis	1/1068	15/18722	0.58579456617987	0.727156079849685	NOTCH2	1
GO:0060766	negative regulation of androgen receptor signaling pathway	1/1068	15/18722	0.58579456617987	0.727156079849685	NCOR2	1
GO:0070207	protein homotrimerization	1/1068	15/18722	0.58579456617987	0.727156079849685	ALOX5AP	1
GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	1/1068	15/18722	0.58579456617987	0.727156079849685	CIB1	1
GO:0072075	metanephric mesenchyme development	1/1068	15/18722	0.58579456617987	0.727156079849685	STAT1	1
GO:0072224	metanephric glomerulus development	1/1068	15/18722	0.58579456617987	0.727156079849685	EGR1	1
GO:0080154	regulation of fertilization	1/1068	15/18722	0.58579456617987	0.727156079849685	LHFPL2	1
GO:0090656	t-circle formation	1/1068	15/18722	0.58579456617987	0.727156079849685	ERCC1	1
GO:0090737	telomere maintenance via telomere trimming	1/1068	15/18722	0.58579456617987	0.727156079849685	ERCC1	1
GO:0097468	programmed cell death in response to reactive oxygen species	1/1068	15/18722	0.58579456617987	0.727156079849685	HGF	1
GO:0098712	L-glutamate import across plasma membrane	1/1068	15/18722	0.58579456617987	0.727156079849685	SLC1A3	1
GO:0099170	postsynaptic modulation of chemical synaptic transmission	1/1068	15/18722	0.58579456617987	0.727156079849685	CYFIP1	1
GO:0106058	positive regulation of calcineurin-mediated signaling	1/1068	15/18722	0.58579456617987	0.727156079849685	CIB1	1
GO:0110156	methylguanosine-cap decapping	1/1068	15/18722	0.58579456617987	0.727156079849685	ZFP36	1
GO:1900102	negative regulation of endoplasmic reticulum unfolded protein response	1/1068	15/18722	0.58579456617987	0.727156079849685	PPP1R15A	1
GO:1901660	calcium ion export	1/1068	15/18722	0.58579456617987	0.727156079849685	CALM3	1
GO:1901841	regulation of high voltage-gated calcium channel activity	1/1068	15/18722	0.58579456617987	0.727156079849685	CALM3	1
GO:1901970	positive regulation of mitotic sister chromatid separation	1/1068	15/18722	0.58579456617987	0.727156079849685	RB1	1
GO:1903729	regulation of plasma membrane organization	1/1068	15/18722	0.58579456617987	0.727156079849685	GSN	1
GO:1904424	regulation of GTP binding	1/1068	15/18722	0.58579456617987	0.727156079849685	CCPG1	1
GO:1904874	positive regulation of telomerase RNA localization to Cajal body	1/1068	15/18722	0.58579456617987	0.727156079849685	NOP10	1
GO:1904889	regulation of excitatory synapse assembly	1/1068	15/18722	0.58579456617987	0.727156079849685	ABI3	1
GO:1990169	stress response to copper ion	1/1068	15/18722	0.58579456617987	0.727156079849685	MT1X	1
GO:1990822	basic amino acid transmembrane transport	1/1068	15/18722	0.58579456617987	0.727156079849685	SLC7A7	1
GO:2000345	regulation of hepatocyte proliferation	1/1068	15/18722	0.58579456617987	0.727156079849685	TNFAIP3	1
GO:0042475	odontogenesis of dentin-containing tooth	5/1068	90/18722	0.588863095239043	0.730675937493136	TCIRG1/FAM20C/RELT/HTRA1/BAX	5
GO:0071715	icosanoid transport	3/1068	53/18722	0.589036384005771	0.730675937493136	SYK/ABCC3/IL1B	3
GO:0099172	presynapse organization	3/1068	53/18722	0.589036384005771	0.730675937493136	C5AR1/SDCBP/ARF6	3
GO:0090068	positive regulation of cell cycle process	13/1068	236/18722	0.592260296172464	0.734506218833973	AIF1/RB1/PLSCR1/RHOA/KMT2E/IL1B/RGCC/ADAM17/NUP62/DYNC1LI1/CDC42/CHMP3/RCC2	13
GO:0035567	non-canonical Wnt signaling pathway	4/1068	72/18722	0.593787782603225	0.736231359128447	RNF213/RHOA/RAC1/CDC42	4
GO:0002065	columnar/cuboidal epithelial cell differentiation	5/1068	91/18722	0.598765651913874	0.741891953553906	HIF1A/PRDM1/FAM20C/CDKN1A/CEBPB	5
GO:0072080	nephron tubule development	5/1068	91/18722	0.598765651913874	0.741891953553906	STAT1/MEF2C/VEGFA/NOTCH2/ACAT1	5
GO:0098661	inorganic anion transmembrane transport	5/1068	91/18722	0.598765651913874	0.741891953553906	PRNP/PTAFR/SLC37A2/SLC1A3/CLCN7	5
GO:0002209	behavioral defense response	2/1068	35/18722	0.601249177333785	0.742242178195631	APOE/MEF2C	2
GO:0007020	microtubule nucleation	2/1068	35/18722	0.601249177333785	0.742242178195631	HSPA1A/PAK1	2
GO:0010664	negative regulation of striated muscle cell apoptotic process	2/1068	35/18722	0.601249177333785	0.742242178195631	NUPR1/JAK2	2
GO:0032205	negative regulation of telomere maintenance	2/1068	35/18722	0.601249177333785	0.742242178195631	ERCC1/ATM	2
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	2/1068	35/18722	0.601249177333785	0.742242178195631	SDCBP/CAMLG	2
GO:0042462	eye photoreceptor cell development	2/1068	35/18722	0.601249177333785	0.742242178195631	VEGFA/PRDM1	2
GO:0043243	positive regulation of protein-containing complex disassembly	2/1068	35/18722	0.601249177333785	0.742242178195631	PLEK/SETX	2
GO:0044273	sulfur compound catabolic process	2/1068	35/18722	0.601249177333785	0.742242178195631	GNS/ACAT1	2
GO:0045907	positive regulation of vasoconstriction	2/1068	35/18722	0.601249177333785	0.742242178195631	RHOA/TBXAS1	2
GO:0046471	phosphatidylglycerol metabolic process	2/1068	35/18722	0.601249177333785	0.742242178195631	LPGAT1/PLA2G15	2
GO:0046627	negative regulation of insulin receptor signaling pathway	2/1068	35/18722	0.601249177333785	0.742242178195631	SOCS3/IL1B	2
GO:0050654	chondroitin sulfate proteoglycan metabolic process	2/1068	35/18722	0.601249177333785	0.742242178195631	DSE/CSGALNACT2	2
GO:0070536	protein K63-linked deubiquitination	2/1068	35/18722	0.601249177333785	0.742242178195631	OTUD1/TNFAIP3	2
GO:0072528	pyrimidine-containing compound biosynthetic process	2/1068	35/18722	0.601249177333785	0.742242178195631	UPP1/TK2	2
GO:0090181	regulation of cholesterol metabolic process	2/1068	35/18722	0.601249177333785	0.742242178195631	APOE/ABCG1	2
GO:0098801	regulation of renal system process	2/1068	35/18722	0.601249177333785	0.742242178195631	CYBA/GNAI2	2
GO:0010659	cardiac muscle cell apoptotic process	3/1068	54/18722	0.601846454545786	0.742300221423786	NUPR1/JAK2/GNB1	3
GO:0032330	regulation of chondrocyte differentiation	3/1068	54/18722	0.601846454545786	0.742300221423786	MAF/TRPS1/TGFBR1	3
GO:0086002	cardiac muscle cell action potential involved in contraction	3/1068	54/18722	0.601846454545786	0.742300221423786	FLNA/KCNE3/ATP1A1	3
GO:2000300	regulation of synaptic vesicle exocytosis	3/1068	54/18722	0.601846454545786	0.742300221423786	RAP1A/LRRK2/CALM3	3
GO:0006939	smooth muscle contraction	6/1068	110/18722	0.603718255609369	0.74443868996073	SLC8A1/DOCK4/RHOA/PTAFR/ROCK1/RGS2	6
GO:0035924	cellular response to vascular endothelial growth factor stimulus	4/1068	73/18722	0.604780254526088	0.744689470751002	CD63/VEGFA/VEGFB/NR4A1	4
GO:0045739	positive regulation of DNA repair	4/1068	73/18722	0.604780254526088	0.744689470751002	ACTR2/PARP9/WAS/DTX3L	4
GO:0086003	cardiac muscle cell contraction	4/1068	73/18722	0.604780254526088	0.744689470751002	FLNA/KCNE3/GSN/ATP1A1	4
GO:1903312	negative regulation of mRNA metabolic process	5/1068	92/18722	0.608532526999318	0.744689470751002	ZFP36/SLC11A1/YBX1/PABPC1/MYD88	5
GO:1903351	cellular response to dopamine	5/1068	92/18722	0.608532526999318	0.744689470751002	ARRB2/FLNA/GNA15/LRRK2/GNB1	5
GO:0001574	ganglioside biosynthetic process	1/1068	16/18722	0.609441938998596	0.744689470751002	ST8SIA4	1
GO:0001977	renal system process involved in regulation of blood volume	1/1068	16/18722	0.609441938998596	0.744689470751002	CYBA	1
GO:0005980	glycogen catabolic process	1/1068	16/18722	0.609441938998596	0.744689470751002	GAA	1
GO:0006004	fucose metabolic process	1/1068	16/18722	0.609441938998596	0.744689470751002	FUOM	1
GO:0006349	regulation of gene expression by genetic imprinting	1/1068	16/18722	0.609441938998596	0.744689470751002	ARID4A	1
GO:0006740	NADPH regeneration	1/1068	16/18722	0.609441938998596	0.744689470751002	PGLS	1
GO:0006750	glutathione biosynthetic process	1/1068	16/18722	0.609441938998596	0.744689470751002	MGST2	1
GO:0009048	dosage compensation by inactivation of X chromosome	1/1068	16/18722	0.609441938998596	0.744689470751002	XIST	1
GO:0010225	response to UV-C	1/1068	16/18722	0.609441938998596	0.744689470751002	CARD16	1
GO:0019081	viral translation	1/1068	16/18722	0.609441938998596	0.744689470751002	PCBP2	1
GO:0021535	cell migration in hindbrain	1/1068	16/18722	0.609441938998596	0.744689470751002	FLNA	1
GO:0035067	negative regulation of histone acetylation	1/1068	16/18722	0.609441938998596	0.744689470751002	SPI1	1
GO:0035970	peptidyl-threonine dephosphorylation	1/1068	16/18722	0.609441938998596	0.744689470751002	DUSP1	1
GO:0042407	cristae formation	1/1068	16/18722	0.609441938998596	0.744689470751002	CHCHD10	1
GO:0042574	retinal metabolic process	1/1068	16/18722	0.609441938998596	0.744689470751002	RDH11	1
GO:0042795	snRNA transcription by RNA polymerase II	1/1068	16/18722	0.609441938998596	0.744689470751002	ELL2	1
GO:0043923	positive regulation by host of viral transcription	1/1068	16/18722	0.609441938998596	0.744689470751002	JUN	1
GO:0044804	autophagy of nucleus	1/1068	16/18722	0.609441938998596	0.744689470751002	ATG3	1
GO:0048557	embryonic digestive tract morphogenesis	1/1068	16/18722	0.609441938998596	0.744689470751002	ID2	1
GO:0050884	neuromuscular process controlling posture	1/1068	16/18722	0.609441938998596	0.744689470751002	GAA	1
GO:0051969	regulation of transmission of nerve impulse	1/1068	16/18722	0.609441938998596	0.744689470751002	TYMP	1
GO:0055089	fatty acid homeostasis	1/1068	16/18722	0.609441938998596	0.744689470751002	APOE	1
GO:0070571	negative regulation of neuron projection regeneration	1/1068	16/18722	0.609441938998596	0.744689470751002	SPP1	1
GO:0072283	metanephric renal vesicle morphogenesis	1/1068	16/18722	0.609441938998596	0.744689470751002	STAT1	1
GO:0090336	positive regulation of brown fat cell differentiation	1/1068	16/18722	0.609441938998596	0.744689470751002	METRNL	1
GO:0090520	sphingolipid mediated signaling pathway	1/1068	16/18722	0.609441938998596	0.744689470751002	RAC1	1
GO:0097428	protein maturation by iron-sulfur cluster transfer	1/1068	16/18722	0.609441938998596	0.744689470751002	CISD3	1
GO:0098884	postsynaptic neurotransmitter receptor internalization	1/1068	16/18722	0.609441938998596	0.744689470751002	NUMB	1
GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential	1/1068	16/18722	0.609441938998596	0.744689470751002	KCNE3	1
GO:0098969	neurotransmitter receptor transport to postsynaptic membrane	1/1068	16/18722	0.609441938998596	0.744689470751002	RAB8A	1
GO:0140239	postsynaptic endocytosis	1/1068	16/18722	0.609441938998596	0.744689470751002	NUMB	1
GO:1902101	positive regulation of metaphase/anaphase transition of cell cycle	1/1068	16/18722	0.609441938998596	0.744689470751002	RB1	1
GO:1902570	protein localization to nucleolus	1/1068	16/18722	0.609441938998596	0.744689470751002	GLUL	1
GO:1904948	midbrain dopaminergic neuron differentiation	1/1068	16/18722	0.609441938998596	0.744689470751002	NR4A2	1
GO:2000001	regulation of DNA damage checkpoint	1/1068	16/18722	0.609441938998596	0.744689470751002	RNASEH2B	1
GO:0090288	negative regulation of cellular response to growth factor stimulus	6/1068	111/18722	0.612585962364384	0.748361750717278	SORL1/SKIL/HTRA1/UBE2D1/SKI/UBE2D3	6
GO:0031113	regulation of microtubule polymerization	3/1068	55/18722	0.614390304029743	0.750396125066658	HSPA1A/RAC1/PAK1	3
GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	4/1068	74/18722	0.615589789445416	0.75121086823856	RHOA/NCOR2/DDX5/PAK1	4
GO:0003230	cardiac atrium development	2/1068	36/18722	0.616723193043878	0.75121086823856	ENG/NOTCH2	2
GO:0007031	peroxisome organization	2/1068	36/18722	0.616723193043878	0.75121086823856	RAB8B/SCP2	2
GO:0008207	C21-steroid hormone metabolic process	2/1068	36/18722	0.616723193043878	0.75121086823856	TSPO/EGR1	2
GO:0009225	nucleotide-sugar metabolic process	2/1068	36/18722	0.616723193043878	0.75121086823856	MGAT1/GNPDA1	2
GO:0042755	eating behavior	2/1068	36/18722	0.616723193043878	0.75121086823856	STAT3/CPT1A	2
GO:0044060	regulation of endocrine process	2/1068	36/18722	0.616723193043878	0.75121086823856	RETN/RAB8B	2
GO:0045652	regulation of megakaryocyte differentiation	2/1068	36/18722	0.616723193043878	0.75121086823856	MEF2C/CIB1	2
GO:0051354	negative regulation of oxidoreductase activity	2/1068	36/18722	0.616723193043878	0.75121086823856	LRRK2/OXA1L	2
GO:0086010	membrane depolarization during action potential	2/1068	36/18722	0.616723193043878	0.75121086823856	YWHAH/SLC8A1	2
GO:0042476	odontogenesis	7/1068	130/18722	0.616727973739218	0.75121086823856	SNX10/RHOA/TCIRG1/FAM20C/RELT/HTRA1/BAX	7
GO:0051028	mRNA transport	7/1068	130/18722	0.616727973739218	0.75121086823856	ZFP36/ZFP36L1/NUP214/MX2/QKI/NUP62/RANBP2	7
GO:0033273	response to vitamin	5/1068	93/18722	0.61816073657429	0.752446500012377	SPP1/HAMP/TSPO/SOD2/KYNU	5
GO:1901019	regulation of calcium ion transmembrane transporter activity	5/1068	93/18722	0.61816073657429	0.752446500012377	VMP1/KCNE3/ATP1B1/CALM3/GSTO1	5
GO:1903350	response to dopamine	5/1068	93/18722	0.61816073657429	0.752446500012377	ARRB2/FLNA/GNA15/LRRK2/GNB1	5
GO:0006661	phosphatidylinositol biosynthetic process	7/1068	131/18722	0.624805570976496	0.758369629852679	INPP5D/SOCS3/MTMR6/EFR3A/ATM/PIK3R1/SOCS6	7
GO:0019827	stem cell population maintenance	7/1068	131/18722	0.624805570976496	0.758369629852679	ZFP36L2/SPI1/KLF4/NOTCH2/STAT3/SKI/KLF10	7
GO:0043627	response to estrogen	4/1068	75/18722	0.626213244733896	0.758369629852679	HMOX1/TGFBR2/ARPC1B/LDHA	4
GO:0010658	striated muscle cell apoptotic process	3/1068	56/18722	0.626664841705364	0.758369629852679	NUPR1/JAK2/GNB1	3
GO:0015800	acidic amino acid transport	3/1068	56/18722	0.626664841705364	0.758369629852679	LRRC8C/SLC6A6/SLC1A3	3
GO:0030166	proteoglycan biosynthetic process	3/1068	56/18722	0.626664841705364	0.758369629852679	DSE/GAL3ST4/CSGALNACT2	3
GO:0045599	negative regulation of fat cell differentiation	3/1068	56/18722	0.626664841705364	0.758369629852679	ZFP36L2/TGFB1/JDP2	3
GO:0090175	regulation of establishment of planar polarity	3/1068	56/18722	0.626664841705364	0.758369629852679	RHOA/RAC1/CDC42	3
GO:0006260	DNA replication	14/1068	260/18722	0.627053106315229	0.758369629852679	SAMHD1/CCDC88A/JUN/NFIC/SLFN11/BCL6/POLD4/RAC1/RECQL/BAZ1A/FAM111A/CDC42/BOD1L1/S100A11	14
GO:0061326	renal tubule development	5/1068	94/18722	0.627647581739366	0.758369629852679	STAT1/MEF2C/VEGFA/NOTCH2/ACAT1	5
GO:1990830	cellular response to leukemia inhibitory factor	5/1068	94/18722	0.627647581739366	0.758369629852679	SNX10/KLF4/SOCS3/MAT2A/B3GNT2	5
GO:0044344	cellular response to fibroblast growth factor stimulus	6/1068	113/18722	0.629984315696574	0.758369629852679	CD44/ZFP36L2/ZFP36/ZFP36L1/SETX/NR4A1	6
GO:0021532	neural tube patterning	2/1068	37/18722	0.631731339165843	0.758369629852679	ATP6AP2/PRKACB	2
GO:0042178	xenobiotic catabolic process	2/1068	37/18722	0.631731339165843	0.758369629852679	ACSL1/GSTO1	2
GO:0043687	post-translational protein modification	2/1068	37/18722	0.631731339165843	0.758369629852679	FAM20C/CRTAP	2
GO:0048009	insulin-like growth factor receptor signaling pathway	2/1068	37/18722	0.631731339165843	0.758369629852679	IGF2R/PIK3R1	2
GO:0048846	axon extension involved in axon guidance	2/1068	37/18722	0.631731339165843	0.758369629852679	ALCAM/VEGFA	2
GO:0050775	positive regulation of dendrite morphogenesis	2/1068	37/18722	0.631731339165843	0.758369629852679	ACTR2/DBNL	2
GO:0060306	regulation of membrane repolarization	2/1068	37/18722	0.631731339165843	0.758369629852679	FLNA/KCNE3	2
GO:0060428	lung epithelium development	2/1068	37/18722	0.631731339165843	0.758369629852679	KLF2/CDC42	2
GO:1902284	neuron projection extension involved in neuron projection guidance	2/1068	37/18722	0.631731339165843	0.758369629852679	ALCAM/VEGFA	2
GO:1905332	positive regulation of morphogenesis of an epithelium	2/1068	37/18722	0.631731339165843	0.758369629852679	ITGAX/VEGFA	2
GO:0001710	mesodermal cell fate commitment	1/1068	17/18722	0.631740453333542	0.758369629852679	KLF4	1
GO:0001829	trophectodermal cell differentiation	1/1068	17/18722	0.631740453333542	0.758369629852679	JUNB	1
GO:0002031	G protein-coupled receptor internalization	1/1068	17/18722	0.631740453333542	0.758369629852679	ARRB2	1
GO:0003184	pulmonary valve morphogenesis	1/1068	17/18722	0.631740453333542	0.758369629852679	NOTCH2	1
GO:0006390	mitochondrial transcription	1/1068	17/18722	0.631740453333542	0.758369629852679	CHCHD10	1
GO:0006577	amino-acid betaine metabolic process	1/1068	17/18722	0.631740453333542	0.758369629852679	CPT1A	1
GO:0006677	glycosylceramide metabolic process	1/1068	17/18722	0.631740453333542	0.758369629852679	GALC	1
GO:0006895	Golgi to endosome transport	1/1068	17/18722	0.631740453333542	0.758369629852679	VPS13C	1
GO:0006901	vesicle coating	1/1068	17/18722	0.631740453333542	0.758369629852679	TMED10	1
GO:0007096	regulation of exit from mitosis	1/1068	17/18722	0.631740453333542	0.758369629852679	RGCC	1
GO:0007379	segment specification	1/1068	17/18722	0.631740453333542	0.758369629852679	MAFB	1
GO:0008334	histone mRNA metabolic process	1/1068	17/18722	0.631740453333542	0.758369629852679	ATM	1
GO:0009151	purine deoxyribonucleotide metabolic process	1/1068	17/18722	0.631740453333542	0.758369629852679	SAMHD1	1
GO:0009200	deoxyribonucleoside triphosphate metabolic process	1/1068	17/18722	0.631740453333542	0.758369629852679	SAMHD1	1
GO:0009251	glucan catabolic process	1/1068	17/18722	0.631740453333542	0.758369629852679	GAA	1
GO:0010566	regulation of ketone biosynthetic process	1/1068	17/18722	0.631740453333542	0.758369629852679	EGR1	1
GO:0015867	ATP transport	1/1068	17/18722	0.631740453333542	0.758369629852679	SLC25A24	1
GO:0016264	gap junction assembly	1/1068	17/18722	0.631740453333542	0.758369629852679	IL1B	1
GO:0021924	cell proliferation in external granule layer	1/1068	17/18722	0.631740453333542	0.758369629852679	ATF5	1
GO:0021930	cerebellar granule cell precursor proliferation	1/1068	17/18722	0.631740453333542	0.758369629852679	ATF5	1
GO:0030322	stabilization of membrane potential	1/1068	17/18722	0.631740453333542	0.758369629852679	CHCHD10	1
GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway	1/1068	17/18722	0.631740453333542	0.758369629852679	TMEM50A	1
GO:0036065	fucosylation	1/1068	17/18722	0.631740453333542	0.758369629852679	FUOM	1
GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	1/1068	17/18722	0.631740453333542	0.758369629852679	ATM	1
GO:0036166	phenotypic switching	1/1068	17/18722	0.631740453333542	0.758369629852679	SOD2	1
GO:0042448	progesterone metabolic process	1/1068	17/18722	0.631740453333542	0.758369629852679	EGR1	1
GO:0043649	dicarboxylic acid catabolic process	1/1068	17/18722	0.631740453333542	0.758369629852679	GLUL	1
GO:0045815	positive regulation of gene expression, epigenetic	1/1068	17/18722	0.631740453333542	0.758369629852679	ZMIZ1	1
GO:0046827	positive regulation of protein export from nucleus	1/1068	17/18722	0.631740453333542	0.758369629852679	IL1B	1
GO:0048521	negative regulation of behavior	1/1068	17/18722	0.631740453333542	0.758369629852679	RETN	1
GO:0051580	regulation of neurotransmitter uptake	1/1068	17/18722	0.631740453333542	0.758369629852679	FLOT1	1
GO:0051797	regulation of hair follicle development	1/1068	17/18722	0.631740453333542	0.758369629852679	HPSE	1
GO:0055003	cardiac myofibril assembly	1/1068	17/18722	0.631740453333542	0.758369629852679	MEF2A	1
GO:0060033	anatomical structure regression	1/1068	17/18722	0.631740453333542	0.758369629852679	SPI1	1
GO:0061298	retina vasculature development in camera-type eye	1/1068	17/18722	0.631740453333542	0.758369629852679	HIF1A	1
GO:0090136	epithelial cell-cell adhesion	1/1068	17/18722	0.631740453333542	0.758369629852679	SERPINB8	1
GO:1900034	regulation of cellular response to heat	1/1068	17/18722	0.631740453333542	0.758369629852679	ATM	1
GO:1901569	fatty acid derivative catabolic process	1/1068	17/18722	0.631740453333542	0.758369629852679	ACAT1	1
GO:1903540	establishment of protein localization to postsynaptic membrane	1/1068	17/18722	0.631740453333542	0.758369629852679	RAB8A	1
GO:1903818	positive regulation of voltage-gated potassium channel activity	1/1068	17/18722	0.631740453333542	0.758369629852679	TREM2	1
GO:0006261	DNA-dependent DNA replication	8/1068	151/18722	0.635839109923679	0.762950375171931	SAMHD1/SLFN11/BCL6/POLD4/RECQL/BAZ1A/FAM111A/BOD1L1	8
GO:0048754	branching morphogenesis of an epithelial tube	8/1068	151/18722	0.635839109923679	0.762950375171931	CTSZ/CTSH/VEGFA/PLXND1/ENG/TGFBR2/STK4/PAK1	8
GO:0008037	cell recognition	12/1068	225/18722	0.636683279326302	0.763793458258054	TREM2/CD9/CD81/CXCR4/LGALS3/HAVCR2/CLEC7A/MSN/CD36/PECAM1/DOCK2/RTN4	12
GO:0045666	positive regulation of neuron differentiation	5/1068	95/18722	0.636990640528113	0.763822554731044	TIMP2/MEF2C/RHOA/BCL6/ARHGEF2	5
GO:1990823	response to leukemia inhibitory factor	5/1068	95/18722	0.636990640528113	0.763822554731044	SNX10/KLF4/SOCS3/MAT2A/B3GNT2	5
GO:0006695	cholesterol biosynthetic process	3/1068	57/18722	0.638667722470155	0.765323346757485	APOE/ACAA2/ABCG1	3
GO:1902017	regulation of cilium assembly	3/1068	57/18722	0.638667722470155	0.765323346757485	CCDC88A/ATG3/SDCCAG8	3
GO:1902653	secondary alcohol biosynthetic process	3/1068	57/18722	0.638667722470155	0.765323346757485	APOE/ACAA2/ABCG1	3
GO:0048568	embryonic organ development	23/1068	427/18722	0.643041253694671	0.770393118325143	MAFB/ID2/GRB2/JUNB/HIF1A/MEF2C/ZFP36L1/VEGFA/ST14/TGFB1/ENG/TGFBR2/VASH1/PRDM1/PBX3/NOTCH2/SH2B3/STK4/ERCC1/SOCS3/CEBPB/TGFBR1/CEBPA	23
GO:0031056	regulation of histone modification	8/1068	152/18722	0.643202974485727	0.770415815832405	SPI1/VEGFA/JDP2/BCL6/LRRK2/KMT2E/IL1B/SKI	8
GO:0043648	dicarboxylic acid metabolic process	5/1068	96/18722	0.646187759582945	0.771425893183431	GLUL/ME2/KYNU/GLS/MTHFD2	5
GO:0044264	cellular polysaccharide metabolic process	5/1068	96/18722	0.646187759582945	0.771425893183431	AOAH/CSGALNACT2/PRKAG2/GAA/B3GNT2	5
GO:0098656	anion transmembrane transport	13/1068	245/18722	0.646227725045433	0.771425893183431	SLC16A3/SLC4A7/PRNP/SLC25A19/PTAFR/LRRC8C/MPC1/SLC37A2/SFXN3/MFSD12/SLC1A3/CLCN7/RGS2	13
GO:0006882	cellular zinc ion homeostasis	2/1068	38/18722	0.646276362626947	0.771425893183431	MT1X/SLC30A1	2
GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway	2/1068	38/18722	0.646276362626947	0.771425893183431	RHOA/NCOR2	2
GO:0042596	fear response	2/1068	38/18722	0.646276362626947	0.771425893183431	APOE/MEF2C	2
GO:2000279	negative regulation of DNA biosynthetic process	2/1068	38/18722	0.646276362626947	0.771425893183431	DUSP1/CDKN1A	2
GO:0021675	nerve development	4/1068	77/18722	0.646891494167558	0.771425893183431	MAFB/TCIRG1/ITGA4/SLC1A3	4
GO:0048644	muscle organ morphogenesis	4/1068	77/18722	0.646891494167558	0.771425893183431	TGFB1/ENG/SERP1/TGFBR1	4
GO:1901989	positive regulation of cell cycle phase transition	6/1068	115/18722	0.646919113854321	0.771425893183431	AIF1/RB1/KMT2E/RGCC/ADAM17/RCC2	6
GO:0098727	maintenance of cell number	7/1068	134/18722	0.648459053969338	0.771425893183431	ZFP36L2/SPI1/KLF4/NOTCH2/STAT3/SKI/KLF10	7
GO:0045604	regulation of epidermal cell differentiation	3/1068	58/18722	0.650397298958224	0.771425893183431	ZFP36/ZFP36L1/ROCK1	3
GO:2000736	regulation of stem cell differentiation	3/1068	58/18722	0.650397298958224	0.771425893183431	ZFP36L2/STAT3/EIF2AK2	3
GO:0001522	pseudouridine synthesis	1/1068	18/18722	0.652766980777529	0.771425893183431	NOP10	1
GO:0001946	lymphangiogenesis	1/1068	18/18722	0.652766980777529	0.771425893183431	VASH1	1
GO:0002076	osteoblast development	1/1068	18/18722	0.652766980777529	0.771425893183431	CLEC5A	1
GO:0002544	chronic inflammatory response	1/1068	18/18722	0.652766980777529	0.771425893183431	TNFAIP3	1
GO:0003128	heart field specification	1/1068	18/18722	0.652766980777529	0.771425893183431	MEF2C	1
GO:0003417	growth plate cartilage development	1/1068	18/18722	0.652766980777529	0.771425893183431	TGFBR2	1
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	1/1068	18/18722	0.652766980777529	0.771425893183431	SRD5A3	1
GO:0006625	protein targeting to peroxisome	1/1068	18/18722	0.652766980777529	0.771425893183431	RAB8B	1
GO:0006991	response to sterol depletion	1/1068	18/18722	0.652766980777529	0.771425893183431	LYN	1
GO:0007250	activation of NF-kappaB-inducing kinase activity	1/1068	18/18722	0.652766980777529	0.771425893183431	IRAK1	1
GO:0007549	dosage compensation	1/1068	18/18722	0.652766980777529	0.771425893183431	XIST	1
GO:0015732	prostaglandin transport	1/1068	18/18722	0.652766980777529	0.771425893183431	IL1B	1
GO:0015936	coenzyme A metabolic process	1/1068	18/18722	0.652766980777529	0.771425893183431	ACAT1	1
GO:0019184	nonribosomal peptide biosynthetic process	1/1068	18/18722	0.652766980777529	0.771425893183431	MGST2	1
GO:0019896	axonal transport of mitochondrion	1/1068	18/18722	0.652766980777529	0.771425893183431	HIF1A	1
GO:0030299	intestinal cholesterol absorption	1/1068	18/18722	0.652766980777529	0.771425893183431	CD36	1
GO:0030728	ovulation	1/1068	18/18722	0.652766980777529	0.771425893183431	RGS2	1
GO:0031000	response to caffeine	1/1068	18/18722	0.652766980777529	0.771425893183431	SLC8A1	1
GO:0031649	heat generation	1/1068	18/18722	0.652766980777529	0.771425893183431	IL1B	1
GO:0032305	positive regulation of icosanoid secretion	1/1068	18/18722	0.652766980777529	0.771425893183431	IL1B	1
GO:0032634	interleukin-5 production	1/1068	18/18722	0.652766980777529	0.771425893183431	LILRB4	1
GO:0032674	regulation of interleukin-5 production	1/1068	18/18722	0.652766980777529	0.771425893183431	LILRB4	1
GO:0033189	response to vitamin A	1/1068	18/18722	0.652766980777529	0.771425893183431	HAMP	1
GO:0036499	PERK-mediated unfolded protein response	1/1068	18/18722	0.652766980777529	0.771425893183431	PPP1R15A	1
GO:0036507	protein demannosylation	1/1068	18/18722	0.652766980777529	0.771425893183431	MAN1A1	1
GO:0036508	protein alpha-1,2-demannosylation	1/1068	18/18722	0.652766980777529	0.771425893183431	MAN1A1	1
GO:0042693	muscle cell fate commitment	1/1068	18/18722	0.652766980777529	0.771425893183431	MEF2C	1
GO:0045116	protein neddylation	1/1068	18/18722	0.652766980777529	0.771425893183431	HIF1A	1
GO:0045623	negative regulation of T-helper cell differentiation	1/1068	18/18722	0.652766980777529	0.771425893183431	BCL6	1
GO:0045653	negative regulation of megakaryocyte differentiation	1/1068	18/18722	0.652766980777529	0.771425893183431	CIB1	1
GO:0046040	IMP metabolic process	1/1068	18/18722	0.652766980777529	0.771425893183431	HPRT1	1
GO:0046112	nucleobase biosynthetic process	1/1068	18/18722	0.652766980777529	0.771425893183431	HPRT1	1
GO:0048535	lymph node development	1/1068	18/18722	0.652766980777529	0.771425893183431	TGFB1	1
GO:0051782	negative regulation of cell division	1/1068	18/18722	0.652766980777529	0.771425893183431	TXNIP	1
GO:0060438	trachea development	1/1068	18/18722	0.652766980777529	0.771425893183431	TGFBR2	1
GO:0060546	negative regulation of necroptotic process	1/1068	18/18722	0.652766980777529	0.771425893183431	ARHGEF2	1
GO:0060973	cell migration involved in heart development	1/1068	18/18722	0.652766980777529	0.771425893183431	ENG	1
GO:0071318	cellular response to ATP	1/1068	18/18722	0.652766980777529	0.771425893183431	P2RX7	1
GO:0072662	protein localization to peroxisome	1/1068	18/18722	0.652766980777529	0.771425893183431	RAB8B	1
GO:0072663	establishment of protein localization to peroxisome	1/1068	18/18722	0.652766980777529	0.771425893183431	RAB8B	1
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	1/1068	18/18722	0.652766980777529	0.771425893183431	VEGFA	1
GO:0090493	catecholamine uptake	1/1068	18/18722	0.652766980777529	0.771425893183431	ACTB	1
GO:0097094	craniofacial suture morphogenesis	1/1068	18/18722	0.652766980777529	0.771425893183431	FOXN3	1
GO:0097107	postsynaptic density assembly	1/1068	18/18722	0.652766980777529	0.771425893183431	ABI3	1
GO:0098877	neurotransmitter receptor transport to plasma membrane	1/1068	18/18722	0.652766980777529	0.771425893183431	RAB8A	1
GO:1902170	cellular response to reactive nitrogen species	1/1068	18/18722	0.652766980777529	0.771425893183431	STAT6	1
GO:1904872	regulation of telomerase RNA localization to Cajal body	1/1068	18/18722	0.652766980777529	0.771425893183431	NOP10	1
GO:2001135	regulation of endocytic recycling	1/1068	18/18722	0.652766980777529	0.771425893183431	SORL1	1
GO:0009416	response to light stimulus	17/1068	320/18722	0.654501368348793	0.773306193039213	GPX1/TIMP1/FOS/DUSP1/ID2/HIF1A/CARD16/CRIP1/MMP2/CDKN1A/ERCC1/BHLHE40/SLC1A3/GNAQ/BAX/PIAS1/PIK3R1	17
GO:0006520	cellular amino acid metabolic process	15/1068	284/18722	0.658328530551046	0.777657782586131	GLUL/SDS/SLC7A7/ALDH1A1/HNMT/IL4I1/DPYD/DDAH2/SDSL/KYNU/GLS/PEPD/ACAT1/FAH/SLC1A3	15
GO:0010463	mesenchymal cell proliferation	2/1068	39/18722	0.660362212185805	0.779377624005819	STAT1/TGFBR2	2
GO:0016233	telomere capping	2/1068	39/18722	0.660362212185805	0.779377624005819	ERCC1/ATM	2
GO:0045823	positive regulation of heart contraction	2/1068	39/18722	0.660362212185805	0.779377624005819	RGS2/ATP1A1	2
GO:2000785	regulation of autophagosome assembly	2/1068	39/18722	0.660362212185805	0.779377624005819	NUPR1/LRRK2	2
GO:0060070	canonical Wnt signaling pathway	16/1068	303/18722	0.661434254674175	0.780453779581882	APOE/ZEB2/NR4A2/ATP6AP2/KLF4/TGFB1/MITF/LRRK2/STK4/TLE3/APC/PFDN5/GNAQ/XIAP/WNK1/EGR1	16
GO:0051055	negative regulation of lipid biosynthetic process	3/1068	59/18722	0.661852575123553	0.780453779581882	APOE/APOC1/ATP1A1	3
GO:2000351	regulation of endothelial cell apoptotic process	3/1068	59/18722	0.661852575123553	0.780453779581882	ITGA4/TNFAIP3/RGCC	3
GO:2001258	negative regulation of cation channel activity	3/1068	59/18722	0.661852575123553	0.780453779581882	KCNE3/CALM3/GSTO1	3
GO:0072073	kidney epithelium development	7/1068	136/18722	0.663729305520048	0.782495812232069	STAT1/MEF2C/PECAM1/VEGFA/NOTCH2/ACAT1/IQGAP1	7
GO:0043010	camera-type eye development	17/1068	322/18722	0.664493622442666	0.783225772542731	VIM/SKIL/HIF1A/KLF4/VEGFA/MAF/TGFBR2/TCIRG1/NOTCH2/MITF/SPRED1/TGFBR1/GNB1/MAX/SKI/PFDN5/BAX	17
GO:0001895	retina homeostasis	4/1068	79/18722	0.666798198708672	0.785598925814846	B2M/LYZ/ACTB/DRAM2	4
GO:0006029	proteoglycan metabolic process	4/1068	79/18722	0.666798198708672	0.785598925814846	DSE/GAL3ST4/HPSE/CSGALNACT2	4
GO:1903313	positive regulation of mRNA metabolic process	6/1068	118/18722	0.67142147382415	0.786082043958425	ZFP36L2/ZFP36/ZFP36L1/PABPC1/BTG2/ROCK1	6
GO:0000028	ribosomal small subunit assembly	1/1068	19/18722	0.672594015878555	0.786082043958425	RPS27L	1
GO:0006490	oligosaccharide-lipid intermediate biosynthetic process	1/1068	19/18722	0.672594015878555	0.786082043958425	SRD5A3	1
GO:0007603	phototransduction, visible light	1/1068	19/18722	0.672594015878555	0.786082043958425	GNAQ	1
GO:0009226	nucleotide-sugar biosynthetic process	1/1068	19/18722	0.672594015878555	0.786082043958425	GNPDA1	1
GO:0009301	snRNA transcription	1/1068	19/18722	0.672594015878555	0.786082043958425	ELL2	1
GO:0034501	protein localization to kinetochore	1/1068	19/18722	0.672594015878555	0.786082043958425	RCC2	1
GO:0035461	vitamin transmembrane transport	1/1068	19/18722	0.672594015878555	0.786082043958425	SLC25A19	1
GO:0036498	IRE1-mediated unfolded protein response	1/1068	19/18722	0.672594015878555	0.786082043958425	BAX	1
GO:0044003	modulation by symbiont of host process	1/1068	19/18722	0.672594015878555	0.786082043958425	CD4	1
GO:0044320	cellular response to leptin stimulus	1/1068	19/18722	0.672594015878555	0.786082043958425	STAT3	1
GO:0044827	modulation by host of viral genome replication	1/1068	19/18722	0.672594015878555	0.786082043958425	IFI27	1
GO:0045603	positive regulation of endothelial cell differentiation	1/1068	19/18722	0.672594015878555	0.786082043958425	BTG1	1
GO:0045947	negative regulation of translational initiation	1/1068	19/18722	0.672594015878555	0.786082043958425	EIF4EBP1	1
GO:0046033	AMP metabolic process	1/1068	19/18722	0.672594015878555	0.786082043958425	HPRT1	1
GO:0046653	tetrahydrofolate metabolic process	1/1068	19/18722	0.672594015878555	0.786082043958425	MTHFD2	1
GO:0051444	negative regulation of ubiquitin-protein transferase activity	1/1068	19/18722	0.672594015878555	0.786082043958425	DTX3L	1
GO:0051571	positive regulation of histone H3-K4 methylation	1/1068	19/18722	0.672594015878555	0.786082043958425	KMT2E	1
GO:0071545	inositol phosphate catabolic process	1/1068	19/18722	0.672594015878555	0.786082043958425	NUDT3	1
GO:0072074	kidney mesenchyme development	1/1068	19/18722	0.672594015878555	0.786082043958425	STAT1	1
GO:0072077	renal vesicle morphogenesis	1/1068	19/18722	0.672594015878555	0.786082043958425	STAT1	1
GO:0086014	atrial cardiac muscle cell action potential	1/1068	19/18722	0.672594015878555	0.786082043958425	FLNA	1
GO:0086026	atrial cardiac muscle cell to AV node cell signaling	1/1068	19/18722	0.672594015878555	0.786082043958425	FLNA	1
GO:0086066	atrial cardiac muscle cell to AV node cell communication	1/1068	19/18722	0.672594015878555	0.786082043958425	FLNA	1
GO:0090670	RNA localization to Cajal body	1/1068	19/18722	0.672594015878555	0.786082043958425	NOP10	1
GO:0090671	telomerase RNA localization to Cajal body	1/1068	19/18722	0.672594015878555	0.786082043958425	NOP10	1
GO:0090672	telomerase RNA localization	1/1068	19/18722	0.672594015878555	0.786082043958425	NOP10	1
GO:0090685	RNA localization to nucleus	1/1068	19/18722	0.672594015878555	0.786082043958425	NOP10	1
GO:0097623	potassium ion export across plasma membrane	1/1068	19/18722	0.672594015878555	0.786082043958425	KCNE3	1
GO:0098780	response to mitochondrial depolarisation	1/1068	19/18722	0.672594015878555	0.786082043958425	VPS13C	1
GO:1901881	positive regulation of protein depolymerization	1/1068	19/18722	0.672594015878555	0.786082043958425	PLEK	1
GO:1903083	protein localization to condensed chromosome	1/1068	19/18722	0.672594015878555	0.786082043958425	RCC2	1
GO:1903204	negative regulation of oxidative stress-induced neuron death	1/1068	19/18722	0.672594015878555	0.786082043958425	HIF1A	1
GO:2000319	regulation of T-helper 17 cell differentiation	1/1068	19/18722	0.672594015878555	0.786082043958425	NFKBIZ	1
GO:2000831	regulation of steroid hormone secretion	1/1068	19/18722	0.672594015878555	0.786082043958425	RETN	1
GO:0007631	feeding behavior	5/1068	99/18722	0.672885793976352	0.786082043958425	FOS/RETN/GLS/STAT3/CPT1A	5
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	3/1068	60/18722	0.673033161392369	0.786082043958425	MBNL1/CELF2/DDX5	3
GO:0019731	antibacterial humoral response	3/1068	60/18722	0.673033161392369	0.786082043958425	HLA-A/HLA-E/RNASE6	3
GO:0055008	cardiac muscle tissue morphogenesis	3/1068	60/18722	0.673033161392369	0.786082043958425	TGFB1/ENG/TGFBR1	3
GO:0014037	Schwann cell differentiation	2/1068	40/18722	0.673993892626309	0.786082043958425	SKI/PLEC	2
GO:0032892	positive regulation of organic acid transport	2/1068	40/18722	0.673993892626309	0.786082043958425	ACSL1/IL1B	2
GO:0055069	zinc ion homeostasis	2/1068	40/18722	0.673993892626309	0.786082043958425	MT1X/SLC30A1	2
GO:0060412	ventricular septum morphogenesis	2/1068	40/18722	0.673993892626309	0.786082043958425	TGFBR2/TGFBR1	2
GO:0070266	necroptotic process	2/1068	40/18722	0.673993892626309	0.786082043958425	ARHGEF2/PPIF	2
GO:0072210	metanephric nephron development	2/1068	40/18722	0.673993892626309	0.786082043958425	STAT1/EGR1	2
GO:1901020	negative regulation of calcium ion transmembrane transporter activity	2/1068	40/18722	0.673993892626309	0.786082043958425	CALM3/GSTO1	2
GO:0140014	mitotic nuclear division	15/1068	287/18722	0.67405515518822	0.786082043958425	DUSP1/RB1/FLNA/RHOA/HSPA1A/KLHDC8B/IL1B/RGCC/ATM/APC/NUP62/DYNC1LI1/CDC42/KPNB1/CHMP1B	15
GO:0007422	peripheral nervous system development	4/1068	80/18722	0.676458642271283	0.788714527592015	PMP22/RUNX1/SKI/PLEC	4
GO:1903322	positive regulation of protein modification by small protein conjugation or removal	7/1068	138/18722	0.678588101375162	0.791026440920366	LAPTM5/LRRK2/GABARAP/UBE2D1/UBE3A/XIAP/PIAS1	7
GO:1903311	regulation of mRNA metabolic process	15/1068	288/18722	0.6792069833235	0.791564849037415	VIM/ZFP36L2/ZFP36/SLC11A1/ZFP36L1/MBNL1/YBX1/CELF2/PABPC1/MYD88/BTG2/QKI/PABPC4/DDX5/ROCK1	15
GO:0031398	positive regulation of protein ubiquitination	6/1068	119/18722	0.679343368401088	0.791564849037415	LAPTM5/LRRK2/GABARAP/UBE2D1/UBE3A/XIAP	6
GO:1901605	alpha-amino acid metabolic process	10/1068	195/18722	0.680589686080992	0.792845843284334	GLUL/SDS/SLC7A7/IL4I1/DDAH2/SDSL/KYNU/GLS/ACAT1/FAH	10
GO:0006626	protein targeting to mitochondrion	5/1068	100/18722	0.681482691571444	0.793372298537112	TSPO/BID/LRRK2/BNIP3L/UBE2D3	5
GO:0044728	DNA methylation or demethylation	5/1068	100/18722	0.681482691571444	0.793372298537112	FOS/SPI1/APOBEC3C/APOBEC3A/KMT2E	5
GO:0060079	excitatory postsynaptic potential	5/1068	100/18722	0.681482691571444	0.793372298537112	MEF2C/ARRB2/P2RX7/LRRK2/PTK2B	5
GO:0030324	lung development	9/1068	177/18722	0.685912934017921	0.798196766811629	CTSZ/LIPA/CTSH/EIF4EBP1/VEGFA/TGFBR2/KLF2/CEBPA/CDC42	9
GO:0021954	central nervous system neuron development	4/1068	81/18722	0.685922610768259	0.798196766811629	NR4A2/ZMIZ1/BTG2/HPRT1	4
GO:0006304	DNA modification	6/1068	120/18722	0.687140637649357	0.79827963004995	FOS/SPI1/APOBEC3C/APOBEC3A/KMT2E/MBD4	6
GO:0007052	mitotic spindle organization	6/1068	120/18722	0.687140637649357	0.79827963004995	FLNA/RHOA/HSPA1A/NUP62/KPNB1/CHMP1B	6
GO:0009167	purine ribonucleoside monophosphate metabolic process	2/1068	41/18722	0.687177331649743	0.79827963004995	IMPDH1/HPRT1	2
GO:0050892	intestinal absorption	2/1068	41/18722	0.687177331649743	0.79827963004995	HAMP/CD36	2
GO:0055023	positive regulation of cardiac muscle tissue growth	2/1068	41/18722	0.687177331649743	0.79827963004995	HAMP/MEF2C	2
GO:1901385	regulation of voltage-gated calcium channel activity	2/1068	41/18722	0.687177331649743	0.79827963004995	KCNE3/CALM3	2
GO:1902116	negative regulation of organelle assembly	2/1068	41/18722	0.687177331649743	0.79827963004995	NUPR1/LRRK2	2
GO:1903524	positive regulation of blood circulation	2/1068	41/18722	0.687177331649743	0.79827963004995	RGS2/ATP1A1	2
GO:0060828	regulation of canonical Wnt signaling pathway	13/1068	253/18722	0.690860170262262	0.79910035049089	APOE/ZEB2/ATP6AP2/TGFB1/LRRK2/STK4/TLE3/APC/PFDN5/GNAQ/XIAP/WNK1/EGR1	13
GO:0006590	thyroid hormone generation	1/1068	20/18722	0.691289925146678	0.79910035049089	CTSB	1
GO:0006851	mitochondrial calcium ion transmembrane transport	1/1068	20/18722	0.691289925146678	0.79910035049089	MICU1	1
GO:0007097	nuclear migration	1/1068	20/18722	0.691289925146678	0.79910035049089	CDC42	1
GO:0007194	negative regulation of adenylate cyclase activity	1/1068	20/18722	0.691289925146678	0.79910035049089	GNAI2	1
GO:0009713	catechol-containing compound biosynthetic process	1/1068	20/18722	0.691289925146678	0.79910035049089	NR4A2	1
GO:0010893	positive regulation of steroid biosynthetic process	1/1068	20/18722	0.691289925146678	0.79910035049089	ABCG1	1
GO:0015919	peroxisomal membrane transport	1/1068	20/18722	0.691289925146678	0.79910035049089	RAB8B	1
GO:0021516	dorsal spinal cord development	1/1068	20/18722	0.691289925146678	0.79910035049089	PBX3	1
GO:0031645	negative regulation of nervous system process	1/1068	20/18722	0.691289925146678	0.79910035049089	CTSC	1
GO:0042423	catecholamine biosynthetic process	1/1068	20/18722	0.691289925146678	0.79910035049089	NR4A2	1
GO:0043651	linoleic acid metabolic process	1/1068	20/18722	0.691289925146678	0.79910035049089	ALOX5	1
GO:0060044	negative regulation of cardiac muscle cell proliferation	1/1068	20/18722	0.691289925146678	0.79910035049089	TGFBR2	1
GO:0060231	mesenchymal to epithelial transition	1/1068	20/18722	0.691289925146678	0.79910035049089	STAT1	1
GO:0071397	cellular response to cholesterol	1/1068	20/18722	0.691289925146678	0.79910035049089	ABCA1	1
GO:0072087	renal vesicle development	1/1068	20/18722	0.691289925146678	0.79910035049089	STAT1	1
GO:0097503	sialylation	1/1068	20/18722	0.691289925146678	0.79910035049089	ST8SIA4	1
GO:1901386	negative regulation of voltage-gated calcium channel activity	1/1068	20/18722	0.691289925146678	0.79910035049089	CALM3	1
GO:1901679	nucleotide transmembrane transport	1/1068	20/18722	0.691289925146678	0.79910035049089	LRRC8C	1
GO:1903817	negative regulation of voltage-gated potassium channel activity	1/1068	20/18722	0.691289925146678	0.79910035049089	KCNE3	1
GO:1904292	regulation of ERAD pathway	1/1068	20/18722	0.691289925146678	0.79910035049089	HERPUD1	1
GO:2000678	negative regulation of transcription regulatory region DNA binding	1/1068	20/18722	0.691289925146678	0.79910035049089	TMSB4X	1
GO:2000757	negative regulation of peptidyl-lysine acetylation	1/1068	20/18722	0.691289925146678	0.79910035049089	SPI1	1
GO:0007588	excretion	3/1068	62/18722	0.694571480624758	0.802378015296766	HMOX1/GNAI2/AQP9	3
GO:0019933	cAMP-mediated signaling	3/1068	62/18722	0.694571480624758	0.802378015296766	AHR/CAP1/RGS2	3
GO:0048663	neuron fate commitment	3/1068	62/18722	0.694571480624758	0.802378015296766	ID2/TGFBR1/CDC42	3
GO:0042752	regulation of circadian rhythm	6/1068	121/18722	0.694812413154449	0.802484542247733	ID2/NR1H3/BHLHE40/KLF10/GNAQ/UBE3A	6
GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	14/1068	273/18722	0.697714083805291	0.805663427394254	FXYD5/ITGB2/CD84/ALCAM/PECAM1/MBP/KLF4/TGFBR2/MILR1/ITGAM/MYADM/ITGAL/ATP2C1/WNK1	14
GO:0045833	negative regulation of lipid metabolic process	5/1068	102/18722	0.698216821452505	0.805899030707533	APOE/APOC1/SORL1/IL1B/ATP1A1	5
GO:1990542	mitochondrial transmembrane transport	5/1068	102/18722	0.698216821452505	0.805899030707533	UCP2/MPC1/SFXN3/CPT1A/MICU1	5
GO:0046688	response to copper ion	2/1068	42/18722	0.69991925849294	0.807691257234368	PRNP/MT1X	2
GO:0019730	antimicrobial humoral response	6/1068	122/18722	0.702357978808428	0.810332190218148	HLA-A/LYZ/HLA-E/SLC11A1/RNASE6/PPP2R3C	6
GO:0030148	sphingolipid biosynthetic process	5/1068	103/18722	0.706352811144181	0.811999130879554	ASAH1/ST8SIA4/SGPL1/HACD4/ACER3	5
GO:0046467	membrane lipid biosynthetic process	7/1068	142/18722	0.707039526792475	0.811999130879554	ASAH1/GAL3ST4/ST8SIA4/SCCPDH/SGPL1/HACD4/ACER3	7
GO:0003002	regionalization	17/1068	331/18722	0.707478953297681	0.811999130879554	C3/C1QA/MAFB/MEF2C/ATP6AP2/ITGAM/PBX3/NOTCH2/LFNG/BTG2/ABI1/FBXL15/TGFBR1/PRKACB/BHLHE40/SKI/BHLHE41	17
GO:0003091	renal water homeostasis	1/1068	21/18722	0.708919181907631	0.811999130879554	PRKACB	1
GO:0006067	ethanol metabolic process	1/1068	21/18722	0.708919181907631	0.811999130879554	ALDH2	1
GO:0006353	DNA-templated transcription, termination	1/1068	21/18722	0.708919181907631	0.811999130879554	SETX	1
GO:0006450	regulation of translational fidelity	1/1068	21/18722	0.708919181907631	0.811999130879554	EIF2S3	1
GO:0007063	regulation of sister chromatid cohesion	1/1068	21/18722	0.708919181907631	0.811999130879554	RB1	1
GO:0008090	retrograde axonal transport	1/1068	21/18722	0.708919181907631	0.811999130879554	KIF5B	1
GO:0010766	negative regulation of sodium ion transport	1/1068	21/18722	0.708919181907631	0.811999130879554	WNK1	1
GO:0022010	central nervous system myelination	1/1068	21/18722	0.708919181907631	0.811999130879554	TLR2	1
GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	1/1068	21/18722	0.708919181907631	0.811999130879554	STX4	1
GO:0031998	regulation of fatty acid beta-oxidation	1/1068	21/18722	0.708919181907631	0.811999130879554	CPT1A	1
GO:0032291	axon ensheathment in central nervous system	1/1068	21/18722	0.708919181907631	0.811999130879554	TLR2	1
GO:0034035	purine ribonucleoside bisphosphate metabolic process	1/1068	21/18722	0.708919181907631	0.811999130879554	PAPSS1	1
GO:0035813	regulation of renal sodium excretion	1/1068	21/18722	0.708919181907631	0.811999130879554	GNAI2	1
GO:0044241	lipid digestion	1/1068	21/18722	0.708919181907631	0.811999130879554	CD36	1
GO:0045717	negative regulation of fatty acid biosynthetic process	1/1068	21/18722	0.708919181907631	0.811999130879554	APOC1	1
GO:0046128	purine ribonucleoside metabolic process	1/1068	21/18722	0.708919181907631	0.811999130879554	HPRT1	1
GO:0046599	regulation of centriole replication	1/1068	21/18722	0.708919181907631	0.811999130879554	NUP62	1
GO:0048199	vesicle targeting, to, from or within Golgi	1/1068	21/18722	0.708919181907631	0.811999130879554	TMED10	1
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	1/1068	21/18722	0.708919181907631	0.811999130879554	PAPSS1	1
GO:0060117	auditory receptor cell development	1/1068	21/18722	0.708919181907631	0.811999130879554	SLC4A7	1
GO:0060972	left/right pattern formation	1/1068	21/18722	0.708919181907631	0.811999130879554	NOTCH2	1
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	1/1068	21/18722	0.708919181907631	0.811999130879554	VEGFA	1
GO:0098698	postsynaptic specialization assembly	1/1068	21/18722	0.708919181907631	0.811999130879554	ABI3	1
GO:0098719	sodium ion import across plasma membrane	1/1068	21/18722	0.708919181907631	0.811999130879554	SLC8A1	1
GO:0098856	intestinal lipid absorption	1/1068	21/18722	0.708919181907631	0.811999130879554	CD36	1
GO:0099500	vesicle fusion to plasma membrane	1/1068	21/18722	0.708919181907631	0.811999130879554	STX4	1
GO:1900118	negative regulation of execution phase of apoptosis	1/1068	21/18722	0.708919181907631	0.811999130879554	PAK2	1
GO:1902259	regulation of delayed rectifier potassium channel activity	1/1068	21/18722	0.708919181907631	0.811999130879554	KCNE3	1
GO:1902644	tertiary alcohol metabolic process	1/1068	21/18722	0.708919181907631	0.811999130879554	AKR1A1	1
GO:2000178	negative regulation of neural precursor cell proliferation	1/1068	21/18722	0.708919181907631	0.811999130879554	BTG2	1
GO:2000291	regulation of myoblast proliferation	1/1068	21/18722	0.708919181907631	0.811999130879554	MALAT1	1
GO:0030323	respiratory tube development	9/1068	181/18722	0.710957029398103	0.81416046914944	CTSZ/LIPA/CTSH/EIF4EBP1/VEGFA/TGFBR2/KLF2/CEBPA/CDC42	9
GO:0001504	neurotransmitter uptake	2/1068	43/18722	0.71222709336978	0.81475034891315	SLC1A3/FLOT1	2
GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	2/1068	43/18722	0.71222709336978	0.81475034891315	FXYD5/ATP2C1	2
GO:0030517	negative regulation of axon extension	2/1068	43/18722	0.71222709336978	0.81475034891315	ARHGAP4/RTN4	2
GO:0046717	acid secretion	2/1068	43/18722	0.71222709336978	0.81475034891315	SGK1/SNX10	2
GO:0098815	modulation of excitatory postsynaptic potential	2/1068	43/18722	0.71222709336978	0.81475034891315	LRRK2/PTK2B	2
GO:0032508	DNA duplex unwinding	4/1068	84/18722	0.713132269242649	0.815440077311577	CHD9/RECQL/SETX/CHD4	4
GO:0042310	vasoconstriction	4/1068	84/18722	0.713132269242649	0.815440077311577	SLC8A1/DOCK4/RHOA/TBXAS1	4
GO:0030104	water homeostasis	3/1068	64/18722	0.715019668736498	0.81690580827909	AQP9/PRKACB/PLEC	3
GO:0046530	photoreceptor cell differentiation	3/1068	64/18722	0.715019668736498	0.81690580827909	VEGFA/PRDM1/STAT3	3
GO:0050771	negative regulation of axonogenesis	3/1068	64/18722	0.715019668736498	0.81690580827909	SPP1/ARHGAP4/RTN4	3
GO:1903018	regulation of glycoprotein metabolic process	3/1068	64/18722	0.715019668736498	0.81690580827909	CST3/SOAT1/HBEGF	3
GO:0031503	protein-containing complex localization	11/1068	220/18722	0.716213548125185	0.817923450938306	TYROBP/NUP214/RAP1A/TNFAIP2/ATM/NUMB/ADAM10/STX7/RCC2/RAB8A/KIF5B	11
GO:0048705	skeletal system morphogenesis	11/1068	220/18722	0.716213548125185	0.817923450938306	ACP5/MEF2C/TGFBR2/MMP2/FGR/SGPL1/DHRS3/FOXN3/TGFBR1/SKI/ZFAND5	11
GO:0007368	determination of left/right symmetry	6/1068	124/18722	0.717068346641404	0.818726364468264	HIF1A/MEF2C/ENG/TGFBR2/NOTCH2/AP1B1	6
GO:0001656	metanephros development	4/1068	85/18722	0.72180840937752	0.820760545871311	CTSH/STAT1/ACAT1/EGR1	4
GO:2000779	regulation of double-strand break repair	4/1068	85/18722	0.72180840937752	0.820760545871311	ACTR2/PARP9/WAS/DTX3L	4
GO:0002792	negative regulation of peptide secretion	2/1068	44/18722	0.724108846898046	0.820760545871311	CD74/UCP2	2
GO:0008542	visual learning	2/1068	44/18722	0.724108846898046	0.820760545871311	HIF1A/PIAS1	2
GO:0009126	purine nucleoside monophosphate metabolic process	2/1068	44/18722	0.724108846898046	0.820760545871311	IMPDH1/HPRT1	2
GO:0048806	genitalia development	2/1068	44/18722	0.724108846898046	0.820760545871311	AXL/BAX	2
GO:0045682	regulation of epidermis development	3/1068	65/18722	0.724839256436121	0.820760545871311	ZFP36/ZFP36L1/ROCK1	3
GO:0051310	metaphase plate congression	3/1068	65/18722	0.724839256436121	0.820760545871311	NUP62/KPNB1/CHMP1B	3
GO:0072577	endothelial cell apoptotic process	3/1068	65/18722	0.724839256436121	0.820760545871311	ITGA4/TNFAIP3/RGCC	3
GO:1902475	L-alpha-amino acid transmembrane transport	3/1068	65/18722	0.724839256436121	0.820760545871311	SLC7A7/SLC1A3/RGS2	3
GO:1905330	regulation of morphogenesis of an epithelium	3/1068	65/18722	0.724839256436121	0.820760545871311	HGF/ITGAX/VEGFA	3
GO:0002029	desensitization of G protein-coupled receptor signaling pathway	1/1068	22/18722	0.725542587806923	0.820760545871311	ARRB2	1
GO:0002089	lens morphogenesis in camera-type eye	1/1068	22/18722	0.725542587806923	0.820760545871311	SKI	1
GO:0006063	uronic acid metabolic process	1/1068	22/18722	0.725542587806923	0.820760545871311	AKR1A1	1
GO:0006359	regulation of transcription by RNA polymerase III	1/1068	22/18722	0.725542587806923	0.820760545871311	CEBPA	1
GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	1/1068	22/18722	0.725542587806923	0.820760545871311	CD9	1
GO:0007398	ectoderm development	1/1068	22/18722	0.725542587806923	0.820760545871311	ITGAM	1
GO:0007413	axonal fasciculation	1/1068	22/18722	0.725542587806923	0.820760545871311	RTN4	1
GO:0009190	cyclic nucleotide biosynthetic process	1/1068	22/18722	0.725542587806923	0.820760545871311	ADCY7	1
GO:0009220	pyrimidine ribonucleotide biosynthetic process	1/1068	22/18722	0.725542587806923	0.820760545871311	UPP1	1
GO:0016137	glycoside metabolic process	1/1068	22/18722	0.725542587806923	0.820760545871311	AKR1A1	1
GO:0019585	glucuronate metabolic process	1/1068	22/18722	0.725542587806923	0.820760545871311	AKR1A1	1
GO:0021854	hypothalamus development	1/1068	22/18722	0.725542587806923	0.820760545871311	BAX	1
GO:0021904	dorsal/ventral neural tube patterning	1/1068	22/18722	0.725542587806923	0.820760545871311	PRKACB	1
GO:0022401	negative adaptation of signaling pathway	1/1068	22/18722	0.725542587806923	0.820760545871311	ARRB2	1
GO:0030277	maintenance of gastrointestinal epithelium	1/1068	22/18722	0.725542587806923	0.820760545871311	TLR4	1
GO:0031281	positive regulation of cyclase activity	1/1068	22/18722	0.725542587806923	0.820760545871311	TIMP2	1
GO:0032402	melanosome transport	1/1068	22/18722	0.725542587806923	0.820760545871311	MYO5A	1
GO:0032891	negative regulation of organic acid transport	1/1068	22/18722	0.725542587806923	0.820760545871311	RGS2	1
GO:0035024	negative regulation of Rho protein signal transduction	1/1068	22/18722	0.725542587806923	0.820760545871311	BCL6	1
GO:0035357	peroxisome proliferator activated receptor signaling pathway	1/1068	22/18722	0.725542587806923	0.820760545871311	FABP5	1
GO:0035809	regulation of urine volume	1/1068	22/18722	0.725542587806923	0.820760545871311	GNAI2	1
GO:0036120	cellular response to platelet-derived growth factor stimulus	1/1068	22/18722	0.725542587806923	0.820760545871311	TLR4	1
GO:0043574	peroxisomal transport	1/1068	22/18722	0.725542587806923	0.820760545871311	RAB8B	1
GO:0046058	cAMP metabolic process	1/1068	22/18722	0.725542587806923	0.820760545871311	ADCY7	1
GO:0048169	regulation of long-term neuronal synaptic plasticity	1/1068	22/18722	0.725542587806923	0.820760545871311	RAB8A	1
GO:0052652	cyclic purine nucleotide metabolic process	1/1068	22/18722	0.725542587806923	0.820760545871311	ADCY7	1
GO:0055093	response to hyperoxia	1/1068	22/18722	0.725542587806923	0.820760545871311	CDKN1A	1
GO:0060343	trabecula formation	1/1068	22/18722	0.725542587806923	0.820760545871311	MMP2	1
GO:0086012	membrane depolarization during cardiac muscle cell action potential	1/1068	22/18722	0.725542587806923	0.820760545871311	SLC8A1	1
GO:0097164	ammonium ion metabolic process	1/1068	22/18722	0.725542587806923	0.820760545871311	HNMT	1
GO:0106030	neuron projection fasciculation	1/1068	22/18722	0.725542587806923	0.820760545871311	RTN4	1
GO:0140467	integrated stress response signaling	1/1068	22/18722	0.725542587806923	0.820760545871311	PPP1R15A	1
GO:1900120	regulation of receptor binding	1/1068	22/18722	0.725542587806923	0.820760545871311	B2M	1
GO:0060541	respiratory system development	10/1068	203/18722	0.727689517043745	0.823016691252997	CTSZ/LIPA/CTSH/EIF4EBP1/VEGFA/TGFBR2/KLF2/CEBPA/SKI/CDC42	10
GO:0099565	chemical synaptic transmission, postsynaptic	5/1068	106/18722	0.729833182532451	0.825268200533341	MEF2C/ARRB2/P2RX7/LRRK2/PTK2B	5
GO:0032413	negative regulation of ion transmembrane transporter activity	4/1068	86/18722	0.730288520342306	0.82561006825206	KCNE3/CALM3/CAB39/GSTO1	4
GO:0019229	regulation of vasoconstriction	3/1068	66/18722	0.734392249561613	0.83007552966788	DOCK4/RHOA/TBXAS1	3
GO:0032309	icosanoid secretion	2/1068	45/18722	0.73557302873385	0.830192859871963	SYK/IL1B	2
GO:0048538	thymus development	2/1068	45/18722	0.73557302873385	0.830192859871963	MAFB/TGFBR1	2
GO:0048546	digestive tract morphogenesis	2/1068	45/18722	0.73557302873385	0.830192859871963	ID2/HIF1A	2
GO:0051180	vitamin transport	2/1068	45/18722	0.73557302873385	0.830192859871963	SLC25A19/SLC2A3	2
GO:0060421	positive regulation of heart growth	2/1068	45/18722	0.73557302873385	0.830192859871963	HAMP/MEF2C	2
GO:0085029	extracellular matrix assembly	2/1068	45/18722	0.73557302873385	0.830192859871963	TGFB1/RGCC	2
GO:1901985	positive regulation of protein acetylation	2/1068	45/18722	0.73557302873385	0.830192859871963	IL1B/TAOK1	2
GO:0036503	ERAD pathway	5/1068	107/18722	0.737350930878281	0.830656185124585	MAN1A1/HM13/CANX/HERPUD1/SDF2L1	5
GO:0071868	cellular response to monoamine stimulus	5/1068	107/18722	0.737350930878281	0.830656185124585	ARRB2/FLNA/GNA15/LRRK2/GNB1	5
GO:0071870	cellular response to catecholamine stimulus	5/1068	107/18722	0.737350930878281	0.830656185124585	ARRB2/FLNA/GNA15/LRRK2/GNB1	5
GO:0048565	digestive tract development	6/1068	127/18722	0.7381776039573	0.830656185124585	ID2/HIF1A/RB1/TGFBR2/PRDM1/CDKN1A	6
GO:0060041	retina development in camera-type eye	7/1068	147/18722	0.740178451154667	0.830656185124585	HIF1A/TCIRG1/GNB1/MAX/SKI/PFDN5/BAX	7
GO:0003283	atrial septum development	1/1068	23/18722	0.741217481722549	0.830656185124585	NOTCH2	1
GO:0006833	water transport	1/1068	23/18722	0.741217481722549	0.830656185124585	AQP9	1
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	1/1068	23/18722	0.741217481722549	0.830656185124585	CARD16	1
GO:0016578	histone deubiquitination	1/1068	23/18722	0.741217481722549	0.830656185124585	USP3	1
GO:0018279	protein N-linked glycosylation via asparagine	1/1068	23/18722	0.741217481722549	0.830656185124585	MGAT1	1
GO:0021884	forebrain neuron development	1/1068	23/18722	0.741217481722549	0.830656185124585	ZMIZ1	1
GO:0021895	cerebral cortex neuron differentiation	1/1068	23/18722	0.741217481722549	0.830656185124585	HPRT1	1
GO:0023058	adaptation of signaling pathway	1/1068	23/18722	0.741217481722549	0.830656185124585	ARRB2	1
GO:0030325	adrenal gland development	1/1068	23/18722	0.741217481722549	0.830656185124585	TSPO	1
GO:0031280	negative regulation of cyclase activity	1/1068	23/18722	0.741217481722549	0.830656185124585	GNAI2	1
GO:0032401	establishment of melanosome localization	1/1068	23/18722	0.741217481722549	0.830656185124585	MYO5A	1
GO:0033081	regulation of T cell differentiation in thymus	1/1068	23/18722	0.741217481722549	0.830656185124585	ADAM8	1
GO:0035812	renal sodium excretion	1/1068	23/18722	0.741217481722549	0.830656185124585	GNAI2	1
GO:0035929	steroid hormone secretion	1/1068	23/18722	0.741217481722549	0.830656185124585	RETN	1
GO:0036119	response to platelet-derived growth factor	1/1068	23/18722	0.741217481722549	0.830656185124585	TLR4	1
GO:0040019	positive regulation of embryonic development	1/1068	23/18722	0.741217481722549	0.830656185124585	CFL1	1
GO:0045724	positive regulation of cilium assembly	1/1068	23/18722	0.741217481722549	0.830656185124585	CCDC88A	1
GO:0051131	chaperone-mediated protein complex assembly	1/1068	23/18722	0.741217481722549	0.830656185124585	HSPA1A	1
GO:0051349	positive regulation of lyase activity	1/1068	23/18722	0.741217481722549	0.830656185124585	TIMP2	1
GO:0051904	pigment granule transport	1/1068	23/18722	0.741217481722549	0.830656185124585	MYO5A	1
GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	1/1068	23/18722	0.741217481722549	0.830656185124585	KCNE3	1
GO:0060384	innervation	1/1068	23/18722	0.741217481722549	0.830656185124585	ITGA4	1
GO:0060487	lung epithelial cell differentiation	1/1068	23/18722	0.741217481722549	0.830656185124585	KLF2	1
GO:0071514	genetic imprinting	1/1068	23/18722	0.741217481722549	0.830656185124585	ARID4A	1
GO:0090208	positive regulation of triglyceride metabolic process	1/1068	23/18722	0.741217481722549	0.830656185124585	NR1H3	1
GO:0090335	regulation of brown fat cell differentiation	1/1068	23/18722	0.741217481722549	0.830656185124585	METRNL	1
GO:0099590	neurotransmitter receptor internalization	1/1068	23/18722	0.741217481722549	0.830656185124585	NUMB	1
GO:1900273	positive regulation of long-term synaptic potentiation	1/1068	23/18722	0.741217481722549	0.830656185124585	LGMN	1
GO:2000810	regulation of bicellular tight junction assembly	1/1068	23/18722	0.741217481722549	0.830656185124585	ROCK1	1
GO:0006513	protein monoubiquitination	3/1068	67/18722	0.743681387721466	0.833244345545064	DTX3L/UBE2W/UBE2D3	3
GO:0050905	neuromuscular process	7/1068	148/18722	0.74647979753084	0.835159149062595	TPP1/RCSD1/GSTO1/SLC1A3/NR4A1/GAA/GM2A	7
GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	2/1068	46/18722	0.746628564691986	0.835159149062595	ALCAM/ITGAL	2
GO:0031057	negative regulation of histone modification	2/1068	46/18722	0.746628564691986	0.835159149062595	SPI1/SKI	2
GO:0035094	response to nicotine	2/1068	46/18722	0.746628564691986	0.835159149062595	B2M/HMOX1	2
GO:0042398	cellular modified amino acid biosynthetic process	2/1068	46/18722	0.746628564691986	0.835159149062595	PLSCR1/MGST2	2
GO:0046839	phospholipid dephosphorylation	2/1068	46/18722	0.746628564691986	0.835159149062595	INPP5D/MTMR6	2
GO:0048701	embryonic cranial skeleton morphogenesis	2/1068	46/18722	0.746628564691986	0.835159149062595	TGFBR2/TGFBR1	2
GO:0090329	regulation of DNA-dependent DNA replication	2/1068	46/18722	0.746628564691986	0.835159149062595	SLFN11/BCL6	2
GO:0017148	negative regulation of translation	12/1068	245/18722	0.74701752119878	0.835421045469143	ZFP36L2/ZFP36/ZFP36L1/YBX1/PABPC1/EIF4EBP1/BTG2/STAT3/EIF2AK2/DAPK1/ROCK1/RGS2	12
GO:0000070	mitotic sister chromatid segregation	8/1068	168/18722	0.748783256069389	0.83722222332168	DUSP1/RB1/ATM/APC/NUP62/DYNC1LI1/KPNB1/CHMP1B	8
GO:0032410	negative regulation of transporter activity	5/1068	109/18722	0.751924914320185	0.840560770182664	KCNE3/CALM3/CAB39/GSTO1/PPIF	5
GO:0009247	glycolipid biosynthetic process	3/1068	68/18722	0.752709718336506	0.841089592077819	GAL3ST4/ST8SIA4/SCCPDH	3
GO:1904888	cranial skeletal system development	3/1068	68/18722	0.752709718336506	0.841089592077819	TGFBR2/FOXN3/TGFBR1	3
GO:0007389	pattern specification process	22/1068	436/18722	0.754765302650669	0.842321880442	C3/C1QA/MAFB/HIF1A/MEF2C/ATP6AP2/ENG/TGFBR2/ITGAM/PBX3/NOTCH2/LFNG/BTG2/ABI1/AP1B1/FBXL15/TGFBR1/PRKACB/APC/BHLHE40/SKI/BHLHE41	22
GO:0003181	atrioventricular valve morphogenesis	1/1068	24/18722	0.755997936801447	0.842321880442	TGFBR2	1
GO:0010288	response to lead ion	1/1068	24/18722	0.755997936801447	0.842321880442	PLSCR1	1
GO:0018196	peptidyl-asparagine modification	1/1068	24/18722	0.755997936801447	0.842321880442	MGAT1	1
GO:0044062	regulation of excretion	1/1068	24/18722	0.755997936801447	0.842321880442	GNAI2	1
GO:0044321	response to leptin	1/1068	24/18722	0.755997936801447	0.842321880442	STAT3	1
GO:0051156	glucose 6-phosphate metabolic process	1/1068	24/18722	0.755997936801447	0.842321880442	PGLS	1
GO:0051647	nucleus localization	1/1068	24/18722	0.755997936801447	0.842321880442	CDC42	1
GO:0051905	establishment of pigment granule localization	1/1068	24/18722	0.755997936801447	0.842321880442	MYO5A	1
GO:0060479	lung cell differentiation	1/1068	24/18722	0.755997936801447	0.842321880442	KLF2	1
GO:0060571	morphogenesis of an epithelial fold	1/1068	24/18722	0.755997936801447	0.842321880442	HIF1A	1
GO:0071676	negative regulation of mononuclear cell migration	1/1068	24/18722	0.755997936801447	0.842321880442	DUSP1	1
GO:0120255	olefinic compound biosynthetic process	1/1068	24/18722	0.755997936801447	0.842321880442	EGR1	1
GO:1901984	negative regulation of protein acetylation	1/1068	24/18722	0.755997936801447	0.842321880442	SPI1	1
GO:0032369	negative regulation of lipid transport	2/1068	47/18722	0.757284721682833	0.842885387417609	APOC1/NR1H3	2
GO:0048512	circadian behavior	2/1068	47/18722	0.757284721682833	0.842885387417609	ID2/EGR1	2
GO:0051972	regulation of telomerase activity	2/1068	47/18722	0.757284721682833	0.842885387417609	KLF4/PARP4	2
GO:1903170	negative regulation of calcium ion transmembrane transport	2/1068	47/18722	0.757284721682833	0.842885387417609	CALM3/GSTO1	2
GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	2/1068	47/18722	0.757284721682833	0.842885387417609	HMOX1/VEGFA	2
GO:0030534	adult behavior	6/1068	130/18722	0.75813916755794	0.843662393925066	CSTB/PPT1/ARRB2/NR4A2/PBX3/ABHD12	6
GO:0030178	negative regulation of Wnt signaling pathway	8/1068	170/18722	0.760292342881474	0.845884016946069	APOE/RNF213/STK4/LRP1/TLE3/APC/PFDN5/EGR1	8
GO:0015807	L-amino acid transport	3/1068	69/18722	0.761480566808992	0.846856788644131	SLC11A1/SLC7A7/SLC1A3	3
GO:0019226	transmission of nerve impulse	3/1068	69/18722	0.761480566808992	0.846856788644131	TYMP/OTOA/PLEC	3
GO:0032392	DNA geometric change	4/1068	90/18722	0.762269520018596	0.847559515767637	CHD9/RECQL/SETX/CHD4	4
GO:0048592	eye morphogenesis	7/1068	151/18722	0.764731031489925	0.850121270275986	HIF1A/VEGFA/PRDM1/NOTCH2/STAT3/SKI/BAX	7
GO:0006805	xenobiotic metabolic process	5/1068	111/18722	0.765887865385891	0.850717967790341	NCEH1/AHR/ACSL1/VKORC1/GSTO1	5
GO:0071867	response to monoamine	5/1068	111/18722	0.765887865385891	0.850717967790341	ARRB2/FLNA/GNA15/LRRK2/GNB1	5
GO:0071869	response to catecholamine	5/1068	111/18722	0.765887865385891	0.850717967790341	ARRB2/FLNA/GNA15/LRRK2/GNB1	5
GO:0006111	regulation of gluconeogenesis	2/1068	48/18722	0.767551039845031	0.850717967790341	FBP1/RANBP2	2
GO:0010569	regulation of double-strand break repair via homologous recombination	2/1068	48/18722	0.767551039845031	0.850717967790341	ACTR2/WAS	2
GO:0042908	xenobiotic transport	2/1068	48/18722	0.767551039845031	0.850717967790341	ABCC3/TMEM30A	2
GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	2/1068	48/18722	0.767551039845031	0.850717967790341	SDCBP/CAMLG	2
GO:0045333	cellular respiration	11/1068	230/18722	0.767766578959525	0.850717967790341	NUPR1/CHCHD10/HIF1A/RHOA/BID/BLOC1S1/SCO2/IFNAR1/OXA1L/PLEC/PPIF	11
GO:0003094	glomerular filtration	1/1068	25/18722	0.76993494629423	0.850717967790341	CYBA	1
GO:0006312	mitotic recombination	1/1068	25/18722	0.76993494629423	0.850717967790341	ERCC1	1
GO:0010560	positive regulation of glycoprotein biosynthetic process	1/1068	25/18722	0.76993494629423	0.850717967790341	SOAT1	1
GO:0015012	heparan sulfate proteoglycan biosynthetic process	1/1068	25/18722	0.76993494629423	0.850717967790341	DSE	1
GO:0015874	norepinephrine transport	1/1068	25/18722	0.76993494629423	0.850717967790341	ACTB	1
GO:0021846	cell proliferation in forebrain	1/1068	25/18722	0.76993494629423	0.850717967790341	NUMB	1
GO:0032331	negative regulation of chondrocyte differentiation	1/1068	25/18722	0.76993494629423	0.850717967790341	TGFBR1	1
GO:0032400	melanosome localization	1/1068	25/18722	0.76993494629423	0.850717967790341	MYO5A	1
GO:0032925	regulation of activin receptor signaling pathway	1/1068	25/18722	0.76993494629423	0.850717967790341	SKI	1
GO:0036315	cellular response to sterol	1/1068	25/18722	0.76993494629423	0.850717967790341	ABCA1	1
GO:0046339	diacylglycerol metabolic process	1/1068	25/18722	0.76993494629423	0.850717967790341	PLA2G15	1
GO:0051204	protein insertion into mitochondrial membrane	1/1068	25/18722	0.76993494629423	0.850717967790341	BAX	1
GO:0051291	protein heterooligomerization	1/1068	25/18722	0.76993494629423	0.850717967790341	MAT2A	1
GO:0060074	synapse maturation	1/1068	25/18722	0.76993494629423	0.850717967790341	PFN1	1
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	1/1068	25/18722	0.76993494629423	0.850717967790341	ERCC1	1
GO:0061436	establishment of skin barrier	1/1068	25/18722	0.76993494629423	0.850717967790341	PLEC	1
GO:0062009	secondary palate development	1/1068	25/18722	0.76993494629423	0.850717967790341	TGFBR2	1
GO:0072202	cell differentiation involved in metanephros development	1/1068	25/18722	0.76993494629423	0.850717967790341	STAT1	1
GO:1903792	negative regulation of anion transport	1/1068	25/18722	0.76993494629423	0.850717967790341	RGS2	1
GO:1905563	negative regulation of vascular endothelial cell proliferation	1/1068	25/18722	0.76993494629423	0.850717967790341	MEF2C	1
GO:2000311	regulation of AMPA receptor activity	1/1068	25/18722	0.76993494629423	0.850717967790341	MEF2C	1
GO:0060415	muscle tissue morphogenesis	3/1068	70/18722	0.769997508281695	0.850717967790341	TGFB1/ENG/TGFBR1	3
GO:0009855	determination of bilateral symmetry	6/1068	133/18722	0.776961414931621	0.857357759232902	HIF1A/MEF2C/ENG/TGFBR2/NOTCH2/AP1B1	6
GO:0034502	protein localization to chromosome	4/1068	92/18722	0.777116685252823	0.857357759232902	SPI1/TPP1/RB1/RCC2	4
GO:0035249	synaptic transmission, glutamatergic	4/1068	92/18722	0.777116685252823	0.857357759232902	GLUL/MEF2C/LRRK2/PTK2B	4
GO:0006376	mRNA splice site selection	2/1068	49/18722	0.777437271298479	0.857357759232902	CELF2/SETX	2
GO:0007622	rhythmic behavior	2/1068	49/18722	0.777437271298479	0.857357759232902	ID2/EGR1	2
GO:0008038	neuron recognition	2/1068	49/18722	0.777437271298479	0.857357759232902	CXCR4/RTN4	2
GO:0009066	aspartate family amino acid metabolic process	2/1068	49/18722	0.777437271298479	0.857357759232902	SDS/SDSL	2
GO:0042461	photoreceptor cell development	2/1068	49/18722	0.777437271298479	0.857357759232902	VEGFA/PRDM1	2
GO:1901799	negative regulation of proteasomal protein catabolic process	2/1068	49/18722	0.777437271298479	0.857357759232902	SDCBP/CAMLG	2
GO:0009799	specification of symmetry	6/1068	134/18722	0.782984963101728	0.858837668141626	HIF1A/MEF2C/ENG/TGFBR2/NOTCH2/AP1B1	6
GO:0001556	oocyte maturation	1/1068	26/18722	0.783076598824463	0.858837668141626	PTK2B	1
GO:0003416	endochondral bone growth	1/1068	26/18722	0.783076598824463	0.858837668141626	TGFBR2	1
GO:0006517	protein deglycosylation	1/1068	26/18722	0.783076598824463	0.858837668141626	MAN1A1	1
GO:0006760	folic acid-containing compound metabolic process	1/1068	26/18722	0.783076598824463	0.858837668141626	MTHFD2	1
GO:0007214	gamma-aminobutyric acid signaling pathway	1/1068	26/18722	0.783076598824463	0.858837668141626	GNAI2	1
GO:0015985	energy coupled proton transport, down electrochemical gradient	1/1068	26/18722	0.783076598824463	0.858837668141626	ATP6V1A	1
GO:0015986	ATP synthesis coupled proton transport	1/1068	26/18722	0.783076598824463	0.858837668141626	ATP6V1A	1
GO:0021952	central nervous system projection neuron axonogenesis	1/1068	26/18722	0.783076598824463	0.858837668141626	NR4A2	1
GO:0033522	histone H2A ubiquitination	1/1068	26/18722	0.783076598824463	0.858837668141626	DTX3L	1
GO:0034643	establishment of mitochondrion localization, microtubule-mediated	1/1068	26/18722	0.783076598824463	0.858837668141626	HIF1A	1
GO:0042278	purine nucleoside metabolic process	1/1068	26/18722	0.783076598824463	0.858837668141626	HPRT1	1
GO:0042634	regulation of hair cycle	1/1068	26/18722	0.783076598824463	0.858837668141626	HPSE	1
GO:0045026	plasma membrane fusion	1/1068	26/18722	0.783076598824463	0.858837668141626	CD9	1
GO:0045745	positive regulation of G protein-coupled receptor signaling pathway	1/1068	26/18722	0.783076598824463	0.858837668141626	C3	1
GO:0047497	mitochondrion transport along microtubule	1/1068	26/18722	0.783076598824463	0.858837668141626	HIF1A	1
GO:0051350	negative regulation of lyase activity	1/1068	26/18722	0.783076598824463	0.858837668141626	GNAI2	1
GO:0051560	mitochondrial calcium ion homeostasis	1/1068	26/18722	0.783076598824463	0.858837668141626	MICU1	1
GO:0051875	pigment granule localization	1/1068	26/18722	0.783076598824463	0.858837668141626	MYO5A	1
GO:0060037	pharyngeal system development	1/1068	26/18722	0.783076598824463	0.858837668141626	TGFBR1	1
GO:0060544	regulation of necroptotic process	1/1068	26/18722	0.783076598824463	0.858837668141626	ARHGEF2	1
GO:0072273	metanephric nephron morphogenesis	1/1068	26/18722	0.783076598824463	0.858837668141626	STAT1	1
GO:0097205	renal filtration	1/1068	26/18722	0.783076598824463	0.858837668141626	CYBA	1
GO:0099637	neurotransmitter receptor transport	1/1068	26/18722	0.783076598824463	0.858837668141626	RAB8A	1
GO:1902186	regulation of viral release from host cell	1/1068	26/18722	0.783076598824463	0.858837668141626	CHMP3	1
GO:1904861	excitatory synapse assembly	1/1068	26/18722	0.783076598824463	0.858837668141626	ABI3	1
GO:2000050	regulation of non-canonical Wnt signaling pathway	1/1068	26/18722	0.783076598824463	0.858837668141626	RNF213	1
GO:0060993	kidney morphogenesis	4/1068	93/18722	0.784260772833881	0.859961619632518	STAT1/VEGFA/LRRK2/PRKX	4
GO:0000271	polysaccharide biosynthetic process	3/1068	72/18722	0.786285060876839	0.861656009035627	TGFB1/CSGALNACT2/B3GNT2	3
GO:0001736	establishment of planar polarity	3/1068	72/18722	0.786285060876839	0.861656009035627	RHOA/RAC1/CDC42	3
GO:0007164	establishment of tissue polarity	3/1068	72/18722	0.786285060876839	0.861656009035627	RHOA/RAC1/CDC42	3
GO:0007632	visual behavior	2/1068	50/18722	0.786953324984328	0.86168834042521	HIF1A/PIAS1	2
GO:0010665	regulation of cardiac muscle cell apoptotic process	2/1068	50/18722	0.786953324984328	0.86168834042521	NUPR1/JAK2	2
GO:0018023	peptidyl-lysine trimethylation	2/1068	50/18722	0.786953324984328	0.86168834042521	KMT2E/ARID4A	2
GO:0099054	presynapse assembly	2/1068	50/18722	0.786953324984328	0.86168834042521	SDCBP/ARF6	2
GO:0010970	transport along microtubule	7/1068	155/18722	0.787553120553695	0.862170143742694	HIF1A/BLOC1S1/BLOC1S2/ARL8B/LAMP1/CDC42/KIF5B	7
GO:0051298	centrosome duplication	3/1068	73/18722	0.794063838291872	0.866790517561691	NUP62/CHMP3/CHMP1B	3
GO:0061035	regulation of cartilage development	3/1068	73/18722	0.794063838291872	0.866790517561691	MAF/TRPS1/TGFBR1	3
GO:0070988	demethylation	3/1068	73/18722	0.794063838291872	0.866790517561691	APOBEC3C/APOBEC3A/JMJD1C	3
GO:0001958	endochondral ossification	1/1068	27/18722	0.795468243692642	0.866790517561691	MEF2C	1
GO:0003171	atrioventricular valve development	1/1068	27/18722	0.795468243692642	0.866790517561691	TGFBR2	1
GO:0006783	heme biosynthetic process	1/1068	27/18722	0.795468243692642	0.866790517561691	TSPO	1
GO:0010561	negative regulation of glycoprotein biosynthetic process	1/1068	27/18722	0.795468243692642	0.866790517561691	HBEGF	1
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	1/1068	27/18722	0.795468243692642	0.866790517561691	RCC2	1
GO:0015813	L-glutamate transmembrane transport	1/1068	27/18722	0.795468243692642	0.866790517561691	SLC1A3	1
GO:0018195	peptidyl-arginine modification	1/1068	27/18722	0.795468243692642	0.866790517561691	KRTCAP2	1
GO:0033561	regulation of water loss via skin	1/1068	27/18722	0.795468243692642	0.866790517561691	PLEC	1
GO:0034453	microtubule anchoring	1/1068	27/18722	0.795468243692642	0.866790517561691	CEP350	1
GO:0035235	ionotropic glutamate receptor signaling pathway	1/1068	27/18722	0.795468243692642	0.866790517561691	PTK2B	1
GO:0036075	replacement ossification	1/1068	27/18722	0.795468243692642	0.866790517561691	MEF2C	1
GO:0042403	thyroid hormone metabolic process	1/1068	27/18722	0.795468243692642	0.866790517561691	CTSB	1
GO:0046174	polyol catabolic process	1/1068	27/18722	0.795468243692642	0.866790517561691	NUDT3	1
GO:0048520	positive regulation of behavior	1/1068	27/18722	0.795468243692642	0.866790517561691	MEF2C	1
GO:0051953	negative regulation of amine transport	1/1068	27/18722	0.795468243692642	0.866790517561691	RGS2	1
GO:0060512	prostate gland morphogenesis	1/1068	27/18722	0.795468243692642	0.866790517561691	CRIP1	1
GO:0098901	regulation of cardiac muscle cell action potential	1/1068	27/18722	0.795468243692642	0.866790517561691	CALM3	1
GO:0099625	ventricular cardiac muscle cell membrane repolarization	1/1068	27/18722	0.795468243692642	0.866790517561691	KCNE3	1
GO:1900746	regulation of vascular endothelial growth factor signaling pathway	1/1068	27/18722	0.795468243692642	0.866790517561691	CD63	1
GO:2000463	positive regulation of excitatory postsynaptic potential	1/1068	27/18722	0.795468243692642	0.866790517561691	PTK2B	1
GO:0051293	establishment of spindle localization	2/1068	51/18722	0.796109217097865	0.867313816971548	CFL1/KPNB1	2
GO:0055123	digestive system development	6/1068	137/18722	0.800315096081978	0.87154394721662	ID2/HIF1A/RB1/TGFBR2/PRDM1/CDKN1A	6
GO:0090090	negative regulation of canonical Wnt signaling pathway	6/1068	137/18722	0.800315096081978	0.87154394721662	APOE/STK4/TLE3/APC/PFDN5/EGR1	6
GO:0051225	spindle assembly	5/1068	117/18722	0.804191047609218	0.875588154338043	FLNA/RHOA/HSPA1A/KPNB1/CHMP1B	5
GO:0010662	regulation of striated muscle cell apoptotic process	2/1068	52/18722	0.804915026656644	0.875734230463892	NUPR1/JAK2	2
GO:0032206	positive regulation of telomere maintenance	2/1068	52/18722	0.804915026656644	0.875734230463892	ERCC1/ATM	2
GO:0035176	social behavior	2/1068	52/18722	0.804915026656644	0.875734230463892	TREM2/ATXN1	2
GO:0000423	mitophagy	1/1068	28/18722	0.807152646780968	0.875734230463892	VPS13C	1
GO:0007064	mitotic sister chromatid cohesion	1/1068	28/18722	0.807152646780968	0.875734230463892	RB1	1
GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	1/1068	28/18722	0.807152646780968	0.875734230463892	LRP1	1
GO:0007271	synaptic transmission, cholinergic	1/1068	28/18722	0.807152646780968	0.875734230463892	APOE	1
GO:0008299	isoprenoid biosynthetic process	1/1068	28/18722	0.807152646780968	0.875734230463892	SRD5A3	1
GO:0009312	oligosaccharide biosynthetic process	1/1068	28/18722	0.807152646780968	0.875734230463892	FBP1	1
GO:0031440	regulation of mRNA 3'-end processing	1/1068	28/18722	0.807152646780968	0.875734230463892	ZFP36L1	1
GO:0042983	amyloid precursor protein biosynthetic process	1/1068	28/18722	0.807152646780968	0.875734230463892	SOAT1	1
GO:0042984	regulation of amyloid precursor protein biosynthetic process	1/1068	28/18722	0.807152646780968	0.875734230463892	SOAT1	1
GO:0045686	negative regulation of glial cell differentiation	1/1068	28/18722	0.807152646780968	0.875734230463892	TREM2	1
GO:0062125	regulation of mitochondrial gene expression	1/1068	28/18722	0.807152646780968	0.875734230463892	CHCHD10	1
GO:0070076	histone lysine demethylation	1/1068	28/18722	0.807152646780968	0.875734230463892	JMJD1C	1
GO:1903020	positive regulation of glycoprotein metabolic process	1/1068	28/18722	0.807152646780968	0.875734230463892	SOAT1	1
GO:1903779	regulation of cardiac conduction	1/1068	28/18722	0.807152646780968	0.875734230463892	SLC8A1	1
GO:0009101	glycoprotein biosynthetic process	15/1068	317/18722	0.807246490423906	0.875734230463892	DSE/MGAT4A/SOAT1/GAL3ST4/PHLDA1/MGAT1/HBEGF/ST8SIA4/CSGALNACT2/SRD5A3/SERP1/MAN1A1/VEGFB/KRTCAP2/B3GNT2	15
GO:0007416	synapse assembly	8/1068	179/18722	0.80741393800243	0.875739820997209	MEF2C/SDCBP/TLR2/PLXND1/ABI3/RAB29/ARF6/DBNL	8
GO:0045913	positive regulation of carbohydrate metabolic process	3/1068	75/18722	0.808912984891696	0.877189402426767	HIF1A/P2RX7/PTAFR	3
GO:0006305	DNA alkylation	3/1068	76/18722	0.81599237148689	0.883676153412969	FOS/SPI1/KMT2E	3
GO:0006306	DNA methylation	3/1068	76/18722	0.81599237148689	0.883676153412969	FOS/SPI1/KMT2E	3
GO:0009952	anterior/posterior pattern specification	9/1068	201/18722	0.816096926620706	0.883676153412969	ATP6AP2/PBX3/LFNG/BTG2/ABI1/TGFBR1/BHLHE40/SKI/BHLHE41	9
GO:0007292	female gamete generation	6/1068	140/18722	0.816555182080592	0.883676153412969	ZMIZ1/PTK2B/ERCC1/ETV6/PRKAR1A/RGS2	6
GO:0006688	glycosphingolipid biosynthetic process	1/1068	29/18722	0.818170137592882	0.883676153412969	ST8SIA4	1
GO:0007143	female meiotic nuclear division	1/1068	29/18722	0.818170137592882	0.883676153412969	PRKAR1A	1
GO:0010390	histone monoubiquitination	1/1068	29/18722	0.818170137592882	0.883676153412969	DTX3L	1
GO:0010458	exit from mitosis	1/1068	29/18722	0.818170137592882	0.883676153412969	RGCC	1
GO:0021591	ventricular system development	1/1068	29/18722	0.818170137592882	0.883676153412969	NUMB	1
GO:0021602	cranial nerve morphogenesis	1/1068	29/18722	0.818170137592882	0.883676153412969	MAFB	1
GO:0032372	negative regulation of sterol transport	1/1068	29/18722	0.818170137592882	0.883676153412969	APOC1	1
GO:0032375	negative regulation of cholesterol transport	1/1068	29/18722	0.818170137592882	0.883676153412969	APOC1	1
GO:0035066	positive regulation of histone acetylation	1/1068	29/18722	0.818170137592882	0.883676153412969	IL1B	1
GO:0048265	response to pain	1/1068	29/18722	0.818170137592882	0.883676153412969	TSPO	1
GO:0051654	establishment of mitochondrion localization	1/1068	29/18722	0.818170137592882	0.883676153412969	HIF1A	1
GO:0070198	protein localization to chromosome, telomeric region	1/1068	29/18722	0.818170137592882	0.883676153412969	TPP1	1
GO:0090114	COPII-coated vesicle budding	1/1068	29/18722	0.818170137592882	0.883676153412969	TMED10	1
GO:0098868	bone growth	1/1068	29/18722	0.818170137592882	0.883676153412969	TGFBR2	1
GO:1900117	regulation of execution phase of apoptosis	1/1068	29/18722	0.818170137592882	0.883676153412969	PAK2	1
GO:1902547	regulation of cellular response to vascular endothelial growth factor stimulus	1/1068	29/18722	0.818170137592882	0.883676153412969	CD63	1
GO:0098813	nuclear chromosome segregation	13/1068	281/18722	0.818558810219879	0.883919019400934	DUSP1/RB1/ACTR2/ACTR3/KLHDC8B/ATM/APC/NUP62/DYNC1LI1/CDC42/RCC2/KPNB1/CHMP1B	13
GO:0048593	camera-type eye morphogenesis	5/1068	120/18722	0.821393100439308	0.886049294820039	HIF1A/VEGFA/NOTCH2/SKI/BAX	5
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	2/1068	54/18722	0.821516794289224	0.886049294820039	HMOX1/VEGFA	2
GO:0030520	intracellular estrogen receptor signaling pathway	2/1068	54/18722	0.821516794289224	0.886049294820039	DDX5/PAK1	2
GO:0035065	regulation of histone acetylation	2/1068	54/18722	0.821516794289224	0.886049294820039	SPI1/IL1B	2
GO:0051703	biological process involved in intraspecies interaction between organisms	2/1068	54/18722	0.821516794289224	0.886049294820039	TREM2/ATXN1	2
GO:0060350	endochondral bone morphogenesis	2/1068	54/18722	0.821516794289224	0.886049294820039	MEF2C/TGFBR2	2
GO:0000380	alternative mRNA splicing, via spliceosome	3/1068	77/18722	0.822847812459296	0.887130228977095	MBNL1/CELF2/DDX5	3
GO:1901983	regulation of protein acetylation	3/1068	77/18722	0.822847812459296	0.887130228977095	SPI1/IL1B/TAOK1	3
GO:0006221	pyrimidine nucleotide biosynthetic process	1/1068	30/18722	0.82855874793102	0.89097309761574	UPP1	1
GO:0006884	cell volume homeostasis	1/1068	30/18722	0.82855874793102	0.89097309761574	P2RX7	1
GO:0010669	epithelial structure maintenance	1/1068	30/18722	0.82855874793102	0.89097309761574	TLR4	1
GO:0019674	NAD metabolic process	1/1068	30/18722	0.82855874793102	0.89097309761574	LDHA	1
GO:0034508	centromere complex assembly	1/1068	30/18722	0.82855874793102	0.89097309761574	RB1	1
GO:0044030	regulation of DNA methylation	1/1068	30/18722	0.82855874793102	0.89097309761574	SPI1	1
GO:0048240	sperm capacitation	1/1068	30/18722	0.82855874793102	0.89097309761574	ABHD2	1
GO:0060218	hematopoietic stem cell differentiation	1/1068	30/18722	0.82855874793102	0.89097309761574	EIF2AK2	1
GO:0060351	cartilage development involved in endochondral bone morphogenesis	1/1068	30/18722	0.82855874793102	0.89097309761574	TGFBR2	1
GO:0060603	mammary gland duct morphogenesis	1/1068	30/18722	0.82855874793102	0.89097309761574	CSF1R	1
GO:0099068	postsynapse assembly	1/1068	30/18722	0.82855874793102	0.89097309761574	ABI3	1
GO:1902751	positive regulation of cell cycle G2/M phase transition	1/1068	30/18722	0.82855874793102	0.89097309761574	RCC2	1
GO:2000648	positive regulation of stem cell proliferation	1/1068	30/18722	0.82855874793102	0.89097309761574	PTPRC	1
GO:0001755	neural crest cell migration	2/1068	55/18722	0.82933288826128	0.891612726251089	HIF1A/CORO1C	2
GO:0034637	cellular carbohydrate biosynthetic process	3/1068	78/18722	0.829484041100902	0.891612726251089	FBP1/CSGALNACT2/B3GNT2	3
GO:0048024	regulation of mRNA splicing, via spliceosome	4/1068	101/18722	0.835013118719404	0.897198484390662	MBNL1/CELF2/QKI/DDX5	4
GO:0051963	regulation of synapse assembly	4/1068	101/18722	0.835013118719404	0.897198484390662	MEF2C/TLR2/ABI3/ARF6	4
GO:0000245	spliceosomal complex assembly	3/1068	79/18722	0.835905850669016	0.897978891142746	CELF2/SCAF11/SETX	3
GO:0098781	ncRNA transcription	2/1068	56/18722	0.836839112207795	0.898284359243044	ELL2/GTF3A	2
GO:0002063	chondrocyte development	1/1068	31/18722	0.838354342688652	0.898284359243044	TGFBR2	1
GO:0006779	porphyrin-containing compound biosynthetic process	1/1068	31/18722	0.838354342688652	0.898284359243044	TSPO	1
GO:0016577	histone demethylation	1/1068	31/18722	0.838354342688652	0.898284359243044	JMJD1C	1
GO:0018200	peptidyl-glutamic acid modification	1/1068	31/18722	0.838354342688652	0.898284359243044	VKORC1	1
GO:0033014	tetrapyrrole biosynthetic process	1/1068	31/18722	0.838354342688652	0.898284359243044	TSPO	1
GO:0048566	embryonic digestive tract development	1/1068	31/18722	0.838354342688652	0.898284359243044	ID2	1
GO:0050482	arachidonic acid secretion	1/1068	31/18722	0.838354342688652	0.898284359243044	SYK	1
GO:0051569	regulation of histone H3-K4 methylation	1/1068	31/18722	0.838354342688652	0.898284359243044	KMT2E	1
GO:0060045	positive regulation of cardiac muscle cell proliferation	1/1068	31/18722	0.838354342688652	0.898284359243044	MEF2C	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	1/1068	31/18722	0.838354342688652	0.898284359243044	KLF4	1
GO:0071711	basement membrane organization	1/1068	31/18722	0.838354342688652	0.898284359243044	CTSS	1
GO:1903963	arachidonate transport	1/1068	31/18722	0.838354342688652	0.898284359243044	SYK	1
GO:0007059	chromosome segregation	16/1068	346/18722	0.839519048664409	0.899353739645255	DUSP1/RB1/ACTR2/ACTR3/PLSCR1/KLHDC8B/ATM/ARL8B/APC/NUP62/DYNC1LI1/CDC42/NR3C1/RCC2/KPNB1/CHMP1B	16
GO:0140694	non-membrane-bounded organelle assembly	17/1068	367/18722	0.843846209008522	0.903809873721712	MEF2A/LCP1/MSN/FLNA/RHOA/HSPA1A/HCK/RPS27L/PRKAR1A/GSN/NUP62/FLII/AKAP13/DBNL/PLEC/KPNB1/CHMP1B	17
GO:0050891	multicellular organismal water homeostasis	2/1068	57/18722	0.844045344561891	0.903843754565582	PRKACB/PLEC	2
GO:0009100	glycoprotein metabolic process	18/1068	387/18722	0.845188931593172	0.904888784697769	CST3/DSE/MGAT4A/HIF1A/SOAT1/GAL3ST4/PHLDA1/MGAT1/HBEGF/ST8SIA4/HPSE/CSGALNACT2/SRD5A3/SERP1/MAN1A1/VEGFB/KRTCAP2/B3GNT2	18
GO:0051053	negative regulation of DNA metabolic process	5/1068	125/18722	0.84733354866686	0.90548399333239	DUSP1/BCL6/CDKN1A/ERCC1/ATM	5
GO:2000027	regulation of animal organ morphogenesis	5/1068	125/18722	0.84733354866686	0.90548399333239	HGF/RHOA/VEGFA/RAC1/CDC42	5
GO:0003338	metanephros morphogenesis	1/1068	32/18722	0.847590743202724	0.90548399333239	STAT1	1
GO:0042044	fluid transport	1/1068	32/18722	0.847590743202724	0.90548399333239	AQP9	1
GO:0042219	cellular modified amino acid catabolic process	1/1068	32/18722	0.847590743202724	0.90548399333239	ABHD12	1
GO:0042744	hydrogen peroxide catabolic process	1/1068	32/18722	0.847590743202724	0.90548399333239	GPX1	1
GO:0048841	regulation of axon extension involved in axon guidance	1/1068	32/18722	0.847590743202724	0.90548399333239	VEGFA	1
GO:0060914	heart formation	1/1068	32/18722	0.847590743202724	0.90548399333239	MEF2C	1
GO:0061037	negative regulation of cartilage development	1/1068	32/18722	0.847590743202724	0.90548399333239	TGFBR1	1
GO:0072337	modified amino acid transport	1/1068	32/18722	0.847590743202724	0.90548399333239	MGST1	1
GO:1903955	positive regulation of protein targeting to mitochondrion	1/1068	32/18722	0.847590743202724	0.90548399333239	UBE2D3	1
GO:1902850	microtubule cytoskeleton organization involved in mitosis	6/1068	147/18722	0.850392678026048	0.908297484289104	FLNA/RHOA/HSPA1A/NUP62/KPNB1/CHMP1B	6
GO:0010559	regulation of glycoprotein biosynthetic process	2/1068	58/18722	0.850961346190594	0.908724999810893	SOAT1/HBEGF	2
GO:0009060	aerobic respiration	8/1068	189/18722	0.851138335419245	0.908734162628066	NUPR1/CHCHD10/HIF1A/RHOA/BID/BLOC1S1/OXA1L/PPIF	8
GO:0006302	double-strand break repair	11/1068	251/18722	0.85379903359582	0.911394576712768	SAMHD1/ACTR2/CIB1/PARP9/WAS/DTX3L/TDP2/ERCC1/RECQL/ATM/SETX	11
GO:0048285	organelle fission	23/1068	488/18722	0.855522898432096	0.911468513823736	DUSP1/RB1/ACTR2/ACTR3/FLNA/RHOA/CORO1C/HSPA1A/STAT2/KLHDC8B/LRRK2/IL1B/RALA/RGCC/ATM/PRKAR1A/DDHD1/APC/NUP62/DYNC1LI1/CDC42/KPNB1/CHMP1B	23
GO:0006482	protein demethylation	1/1068	33/18722	0.85629984359114	0.911468513823736	JMJD1C	1
GO:0006654	phosphatidic acid biosynthetic process	1/1068	33/18722	0.85629984359114	0.911468513823736	AGPAT2	1
GO:0008214	protein dealkylation	1/1068	33/18722	0.85629984359114	0.911468513823736	JMJD1C	1
GO:0018345	protein palmitoylation	1/1068	33/18722	0.85629984359114	0.911468513823736	GLUL	1
GO:0032228	regulation of synaptic transmission, GABAergic	1/1068	33/18722	0.85629984359114	0.911468513823736	KIF5B	1
GO:0040020	regulation of meiotic nuclear division	1/1068	33/18722	0.85629984359114	0.911468513823736	PRKAR1A	1
GO:0042558	pteridine-containing compound metabolic process	1/1068	33/18722	0.85629984359114	0.911468513823736	MTHFD2	1
GO:0048333	mesodermal cell differentiation	1/1068	33/18722	0.85629984359114	0.911468513823736	KLF4	1
GO:0048730	epidermis morphogenesis	1/1068	33/18722	0.85629984359114	0.911468513823736	KLF4	1
GO:0050974	detection of mechanical stimulus involved in sensory perception	1/1068	33/18722	0.85629984359114	0.911468513823736	CXCR4	1
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	1/1068	33/18722	0.85629984359114	0.911468513823736	ERCC1	1
GO:0099174	regulation of presynapse organization	1/1068	33/18722	0.85629984359114	0.911468513823736	ARF6	1
GO:1905606	regulation of presynapse assembly	1/1068	33/18722	0.85629984359114	0.911468513823736	ARF6	1
GO:0016079	synaptic vesicle exocytosis	4/1068	105/18722	0.856402032076787	0.911468513823736	RAP1A/LRRK2/STX4/CALM3	4
GO:0051568	histone H3-K4 methylation	2/1068	59/18722	0.85759674166663	0.912560050884074	KMT2E/ARID4A	2
GO:0046785	microtubule polymerization	3/1068	83/18722	0.85954606184865	0.914453972739613	HSPA1A/RAC1/PAK1	3
GO:0002183	cytoplasmic translational initiation	1/1068	34/18722	0.864511720472978	0.917746457539285	EIF2S3	1
GO:0006356	regulation of transcription by RNA polymerase I	1/1068	34/18722	0.864511720472978	0.917746457539285	FLNA	1
GO:0009303	rRNA transcription	1/1068	34/18722	0.864511720472978	0.917746457539285	GTF3A	1
GO:0032212	positive regulation of telomere maintenance via telomerase	1/1068	34/18722	0.864511720472978	0.917746457539285	ATM	1
GO:0042573	retinoic acid metabolic process	1/1068	34/18722	0.864511720472978	0.917746457539285	SCPEP1	1
GO:0051973	positive regulation of telomerase activity	1/1068	34/18722	0.864511720472978	0.917746457539285	KLF4	1
GO:0070050	neuron cellular homeostasis	1/1068	34/18722	0.864511720472978	0.917746457539285	TAOK1	1
GO:0086004	regulation of cardiac muscle cell contraction	1/1068	34/18722	0.864511720472978	0.917746457539285	ATP1A1	1
GO:0086019	cell-cell signaling involved in cardiac conduction	1/1068	34/18722	0.864511720472978	0.917746457539285	FLNA	1
GO:2000352	negative regulation of endothelial cell apoptotic process	1/1068	34/18722	0.864511720472978	0.917746457539285	TNFAIP3	1
GO:2000758	positive regulation of peptidyl-lysine acetylation	1/1068	34/18722	0.864511720472978	0.917746457539285	IL1B	1
GO:0015844	monoamine transport	3/1068	84/18722	0.864968794908131	0.91805106556339	ACTB/SYK/LILRB1	3
GO:0021761	limbic system development	4/1068	107/18722	0.866181616780191	0.919157522939215	BTG2/ARPC5/BAX/KIF5B	4
GO:0030902	hindbrain development	6/1068	151/18722	0.867323945486774	0.920188755376845	AIF1/MAFB/C5AR1/FLNA/ATF5/PAK1	6
GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	5/1068	130/18722	0.870076171252038	0.922702608068	SORL1/LRRK2/TMED5/TMED10/BCAP29	5
GO:0007098	centrosome cycle	5/1068	130/18722	0.870076171252038	0.922702608068	ATF5/NUP62/SDCCAG8/CHMP3/CHMP1B	5
GO:0030433	ubiquitin-dependent ERAD pathway	3/1068	85/18722	0.87020636998852	0.922702608068	MAN1A1/CANX/HERPUD1	3
GO:0000731	DNA synthesis involved in DNA repair	1/1068	35/18722	0.87225473644766	0.92287971722972	POLD4	1
GO:0006298	mismatch repair	1/1068	35/18722	0.87225473644766	0.92287971722972	ERCC1	1
GO:0015695	organic cation transport	1/1068	35/18722	0.87225473644766	0.92287971722972	SLC25A19	1
GO:0018149	peptide cross-linking	1/1068	35/18722	0.87225473644766	0.92287971722972	CSTA	1
GO:0021955	central nervous system neuron axonogenesis	1/1068	35/18722	0.87225473644766	0.92287971722972	NR4A2	1
GO:0033146	regulation of intracellular estrogen receptor signaling pathway	1/1068	35/18722	0.87225473644766	0.92287971722972	PAK1	1
GO:0033280	response to vitamin D	1/1068	35/18722	0.87225473644766	0.92287971722972	SPP1	1
GO:0040001	establishment of mitotic spindle localization	1/1068	35/18722	0.87225473644766	0.92287971722972	KPNB1	1
GO:0045922	negative regulation of fatty acid metabolic process	1/1068	35/18722	0.87225473644766	0.92287971722972	APOC1	1
GO:0071108	protein K48-linked deubiquitination	1/1068	35/18722	0.87225473644766	0.92287971722972	TNFAIP3	1
GO:0086005	ventricular cardiac muscle cell action potential	1/1068	35/18722	0.87225473644766	0.92287971722972	KCNE3	1
GO:0048864	stem cell development	3/1068	86/18722	0.875263641662479	0.925881711509653	HIF1A/PTPRC/CORO1C	3
GO:0031124	mRNA 3'-end processing	2/1068	62/18722	0.875913167837102	0.926387192012741	ZFP36L1/PABPC1	2
GO:0010092	specification of animal organ identity	1/1068	36/18722	0.879555637687768	0.929510814916411	MEF2C	1
GO:0043949	regulation of cAMP-mediated signaling	1/1068	36/18722	0.879555637687768	0.929510814916411	RGS2	1
GO:0051955	regulation of amino acid transport	1/1068	36/18722	0.879555637687768	0.929510814916411	RGS2	1
GO:1903749	positive regulation of establishment of protein localization to mitochondrion	1/1068	36/18722	0.879555637687768	0.929510814916411	UBE2D3	1
GO:0001756	somitogenesis	2/1068	63/18722	0.881519137729418	0.931221078149558	LFNG/ABI1	2
GO:2000756	regulation of peptidyl-lysine acetylation	2/1068	63/18722	0.881519137729418	0.931221078149558	SPI1/IL1B	2
GO:0070085	glycosylation	10/1068	240/18722	0.883874736800266	0.933526733171704	MGAT4A/MGAT1/FUOM/ST8SIA4/SRD5A3/SERP1/MAN1A1/VEGFB/KRTCAP2/B3GNT2	10
GO:0090305	nucleic acid phosphodiester bond hydrolysis	11/1068	261/18722	0.88487215030141	0.93439728434959	RNASET2/SAMHD1/DNASE2/ZFP36/PLD3/PLSCR1/RNASE6/RNASE1/TDP2/ERCC1/BAX	11
GO:0000154	rRNA modification	1/1068	37/18722	0.886439645980044	0.934516484415922	NOP10	1
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1/1068	37/18722	0.886439645980044	0.934516484415922	PABPC1	1
GO:0007340	acrosome reaction	1/1068	37/18722	0.886439645980044	0.934516484415922	ABHD2	1
GO:0032885	regulation of polysaccharide biosynthetic process	1/1068	37/18722	0.886439645980044	0.934516484415922	TGFB1	1
GO:0033260	nuclear DNA replication	1/1068	37/18722	0.886439645980044	0.934516484415922	BCL6	1
GO:0046473	phosphatidic acid metabolic process	1/1068	37/18722	0.886439645980044	0.934516484415922	AGPAT2	1
GO:0051567	histone H3-K9 methylation	1/1068	37/18722	0.886439645980044	0.934516484415922	ARID4A	1
GO:1904358	positive regulation of telomere maintenance via telomere lengthening	1/1068	37/18722	0.886439645980044	0.934516484415922	ATM	1
GO:0017156	calcium-ion regulated exocytosis	2/1068	64/18722	0.886890088342093	0.934516484415922	GNAI2/ARL8B	2
GO:0046888	negative regulation of hormone secretion	2/1068	64/18722	0.886890088342093	0.934516484415922	UCP2/IL1B	2
GO:1903051	negative regulation of proteolysis involved in cellular protein catabolic process	2/1068	64/18722	0.886890088342093	0.934516484415922	SDCBP/CAMLG	2
GO:0043588	skin development	11/1068	263/18722	0.890393602095485	0.93802496620602	TXNIP/ASAH1/ZFP36/ZFP36L1/ST14/HPSE/STK4/ADAM9/CSTA/ROCK1/PLEC	11
GO:0033692	cellular polysaccharide biosynthetic process	2/1068	65/18722	0.892034559196251	0.939203606131311	CSGALNACT2/B3GNT2	2
GO:0046513	ceramide biosynthetic process	2/1068	65/18722	0.892034559196251	0.939203606131311	ASAH1/ST8SIA4	2
GO:0048645	animal organ formation	2/1068	65/18722	0.892034559196251	0.939203606131311	MEF2C/TGFBR2	2
GO:0007007	inner mitochondrial membrane organization	1/1068	38/18722	0.892930545530127	0.939230647890949	CHCHD10	1
GO:0010719	negative regulation of epithelial to mesenchymal transition	1/1068	38/18722	0.892930545530127	0.939230647890949	SPRED1	1
GO:0042491	inner ear auditory receptor cell differentiation	1/1068	38/18722	0.892930545530127	0.939230647890949	SLC4A7	1
GO:0046676	negative regulation of insulin secretion	1/1068	38/18722	0.892930545530127	0.939230647890949	UCP2	1
GO:1903725	regulation of phospholipid metabolic process	1/1068	38/18722	0.892930545530127	0.939230647890949	APOC1	1
GO:0000819	sister chromatid segregation	8/1068	202/18722	0.895694248973999	0.941954037704872	DUSP1/RB1/ATM/APC/NUP62/DYNC1LI1/KPNB1/CHMP1B	8
GO:0050909	sensory perception of taste	2/1068	66/18722	0.896960881372334	0.942647360914105	CD36/GNB1	2
GO:1902476	chloride transmembrane transport	2/1068	66/18722	0.896960881372334	0.942647360914105	SLC1A3/CLCN7	2
GO:0050684	regulation of mRNA processing	5/1068	137/18722	0.897052297682344	0.942647360914105	ZFP36L1/MBNL1/CELF2/QKI/DDX5	5
GO:0060078	regulation of postsynaptic membrane potential	5/1068	137/18722	0.897052297682344	0.942647360914105	MEF2C/ARRB2/P2RX7/LRRK2/PTK2B	5
GO:0014033	neural crest cell differentiation	3/1068	91/18722	0.898012758895651	0.943472906347534	HIF1A/MEF2C/CORO1C	3
GO:0001941	postsynaptic membrane organization	1/1068	39/18722	0.899050764828662	0.943644801987057	APOE	1
GO:0017158	regulation of calcium ion-dependent exocytosis	1/1068	39/18722	0.899050764828662	0.943644801987057	GNAI2	1
GO:0036297	interstrand cross-link repair	1/1068	39/18722	0.899050764828662	0.943644801987057	ERCC1	1
GO:0086091	regulation of heart rate by cardiac conduction	1/1068	39/18722	0.899050764828662	0.943644801987057	KCNE3	1
GO:1903115	regulation of actin filament-based movement	1/1068	39/18722	0.899050764828662	0.943644801987057	ATP1A1	1
GO:0006486	protein glycosylation	9/1068	226/18722	0.903321019226525	0.947477339838861	MGAT4A/MGAT1/ST8SIA4/SRD5A3/SERP1/MAN1A1/VEGFB/KRTCAP2/B3GNT2	9
GO:0043413	macromolecule glycosylation	9/1068	226/18722	0.903321019226525	0.947477339838861	MGAT4A/MGAT1/ST8SIA4/SRD5A3/SERP1/MAN1A1/VEGFB/KRTCAP2/B3GNT2	9
GO:0030326	embryonic limb morphogenesis	4/1068	116/18722	0.903404542896764	0.947477339838861	MBNL1/NOTCH2/SKI/BAX	4
GO:0035113	embryonic appendage morphogenesis	4/1068	116/18722	0.903404542896764	0.947477339838861	MBNL1/NOTCH2/SKI/BAX	4
GO:0009069	serine family amino acid metabolic process	1/1068	40/18722	0.904821453859492	0.948410366166631	SDS	1
GO:0009187	cyclic nucleotide metabolic process	1/1068	40/18722	0.904821453859492	0.948410366166631	ADCY7	1
GO:0032094	response to food	1/1068	40/18722	0.904821453859492	0.948410366166631	PLEC	1
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	18/1068	412/18722	0.905558332605446	0.948998400221205	IFI27/ARRB2/SDCBP/HSPA1A/PLK3/LRRK2/GABARAP/MAN1A1/FBXL15/UBE2W/CEBPA/CANX/HERPUD1/PIAS1/UBE2D3/CAMLG/SUMO2/PCBP2	18
GO:0021953	central nervous system neuron differentiation	6/1068	162/18722	0.905833725609594	0.949102676386285	B2M/NR4A2/ZMIZ1/ZSWIM6/BTG2/HPRT1	6
GO:0061912	selective autophagy	2/1068	68/18722	0.906191338792188	0.949293042928101	VPS13C/RAB7A	2
GO:0048863	stem cell differentiation	8/1068	206/18722	0.906923463989831	0.949875584566989	ZFP36L2/A2M/HIF1A/MEF2C/PTPRC/CORO1C/STAT3/EIF2AK2	8
GO:0006119	oxidative phosphorylation	5/1068	141/18722	0.910178196923757	0.951970102252138	NUPR1/CHCHD10/RHOA/BID/PPIF	5
GO:0002251	organ or tissue specific immune response	1/1068	41/18722	0.910262556914735	0.951970102252138	IL6R	1
GO:0007099	centriole replication	1/1068	41/18722	0.910262556914735	0.951970102252138	NUP62	1
GO:0030488	tRNA methylation	1/1068	41/18722	0.910262556914735	0.951970102252138	TRMT1	1
GO:0031062	positive regulation of histone methylation	1/1068	41/18722	0.910262556914735	0.951970102252138	KMT2E	1
GO:0044786	cell cycle DNA replication	1/1068	41/18722	0.910262556914735	0.951970102252138	BCL6	1
GO:0006368	transcription elongation from RNA polymerase II promoter	2/1068	69/18722	0.910511063329	0.951970102252138	ELL2/ZMIZ1	2
GO:0007004	telomere maintenance via telomerase	2/1068	69/18722	0.910511063329	0.951970102252138	ATM/NOP10	2
GO:0045665	negative regulation of neuron differentiation	2/1068	69/18722	0.910511063329	0.951970102252138	B2M/RHOA	2
GO:0031023	microtubule organizing center organization	5/1068	143/18722	0.916173868787269	0.957705191006607	ATF5/NUP62/SDCCAG8/CHMP3/CHMP1B	5
GO:0035282	segmentation	3/1068	96/18722	0.916956629378244	0.958152202193068	MAFB/LFNG/ABI1	3
GO:0042158	lipoprotein biosynthetic process	3/1068	96/18722	0.916956629378244	0.958152202193068	APOE/GLUL/ABCA1	3
GO:0006284	base-excision repair	1/1068	43/18722	0.920230161930694	0.960642668558333	MBD4	1
GO:0016266	O-glycan processing	1/1068	43/18722	0.920230161930694	0.960642668558333	B3GNT2	1
GO:0042181	ketone biosynthetic process	1/1068	43/18722	0.920230161930694	0.960642668558333	EGR1	1
GO:0045494	photoreceptor cell maintenance	1/1068	43/18722	0.920230161930694	0.960642668558333	DRAM2	1
GO:0090278	negative regulation of peptide hormone secretion	1/1068	43/18722	0.920230161930694	0.960642668558333	UCP2	1
GO:0015980	energy derivation by oxidation of organic compounds	13/1068	318/18722	0.921359570063633	0.961625365840067	NUPR1/CHCHD10/HIF1A/RHOA/BID/BLOC1S1/PRKAG2/SCO2/IFNAR1/OXA1L/GAA/PLEC/PPIF	13
GO:0009566	fertilization	7/1068	190/18722	0.921706151246261	0.961625365840067	CD9/LHFPL2/GNPDA1/ABHD2/FNDC3A/UBE3A/BAX	7
GO:0099111	microtubule-based transport	7/1068	190/18722	0.921706151246261	0.961625365840067	HIF1A/BLOC1S1/BLOC1S2/ARL8B/LAMP1/CDC42/KIF5B	7
GO:0001707	mesoderm formation	2/1068	72/18722	0.922377179817131	0.961953471645388	KLF4/PRKAR1A	2
GO:0005977	glycogen metabolic process	2/1068	72/18722	0.922377179817131	0.961953471645388	PRKAG2/GAA	2
GO:0006378	mRNA polyadenylation	1/1068	44/18722	0.924791122745406	0.963912091623375	PABPC1	1
GO:0007528	neuromuscular junction development	1/1068	44/18722	0.924791122745406	0.963912091623375	LRRK2	1
GO:0032881	regulation of polysaccharide metabolic process	1/1068	44/18722	0.924791122745406	0.963912091623375	TGFB1	1
GO:0006073	cellular glucan metabolic process	2/1068	73/18722	0.925991640141786	0.96460441895851	PRKAG2/GAA	2
GO:0044042	glucan metabolic process	2/1068	73/18722	0.925991640141786	0.96460441895851	PRKAG2/GAA	2
GO:0072088	nephron epithelium morphogenesis	2/1068	73/18722	0.925991640141786	0.96460441895851	STAT1/VEGFA	2
GO:0006903	vesicle targeting	1/1068	45/18722	0.929091533972942	0.966713829023909	TMED10	1
GO:0043631	RNA polyadenylation	1/1068	45/18722	0.929091533972942	0.966713829023909	PABPC1	1
GO:0045910	negative regulation of DNA recombination	1/1068	45/18722	0.929091533972942	0.966713829023909	BCL6	1
GO:0048599	oocyte development	1/1068	45/18722	0.929091533972942	0.966713829023909	PTK2B	1
GO:0060119	inner ear receptor cell development	1/1068	45/18722	0.929091533972942	0.966713829023909	SLC4A7	1
GO:0098534	centriole assembly	1/1068	45/18722	0.929091533972942	0.966713829023909	NUP62	1
GO:0048332	mesoderm morphogenesis	2/1068	74/18722	0.929446824721131	0.966897063079858	KLF4/PRKAR1A	2
GO:0006910	phagocytosis, recognition	3/1068	100/18722	0.929738497844843	0.967014058282724	TREM2/CLEC7A/CD36	3
GO:0006278	RNA-dependent DNA biosynthetic process	2/1068	75/18722	0.932749121702759	0.969437284309031	ATM/NOP10	2
GO:0061333	renal tubule morphogenesis	2/1068	75/18722	0.932749121702759	0.969437284309031	MEF2C/VEGFA	2
GO:1903363	negative regulation of cellular protein catabolic process	2/1068	75/18722	0.932749121702759	0.969437284309031	SDCBP/CAMLG	2
GO:0010830	regulation of myotube differentiation	1/1068	46/18722	0.93314626662363	0.969437284309031	BHLHE41	1
GO:0031018	endocrine pancreas development	1/1068	46/18722	0.93314626662363	0.969437284309031	IL6R	1
GO:0050919	negative chemotaxis	1/1068	46/18722	0.93314626662363	0.969437284309031	RHOA	1
GO:0006310	DNA recombination	12/1068	305/18722	0.935739139411673	0.971741738062833	SAMHD1/PTPRC/ACTR2/WAS/TGFB1/BCL6/STAT6/ERCC1/RECQL/ATM/TFPT/SETX	12
GO:0021536	diencephalon development	2/1068	76/18722	0.935904709546431	0.971741738062833	NR4A2/BAX	2
GO:0072028	nephron morphogenesis	2/1068	76/18722	0.935904709546431	0.971741738062833	STAT1/VEGFA	2
GO:0016073	snRNA metabolic process	1/1068	47/18722	0.93696934368756	0.972285880488091	NOP10	1
GO:0016574	histone ubiquitination	1/1068	47/18722	0.93696934368756	0.972285880488091	DTX3L	1
GO:0035315	hair cell differentiation	1/1068	47/18722	0.93696934368756	0.972285880488091	SLC4A7	1
GO:0002027	regulation of heart rate	3/1068	103/18722	0.938109596944229	0.97328194291695	SLC8A1/KCNE3/CALM3	3
GO:0050954	sensory perception of mechanical stimulus	6/1068	175/18722	0.938559913814183	0.973561955967192	GPX1/CXCR4/MBP/OTOA/SCARB2/SLC1A3	6
GO:0035036	sperm-egg recognition	1/1068	48/18722	0.940573988450167	0.975276180183917	CD9	1
GO:0061647	histone H3-K9 modification	1/1068	48/18722	0.940573988450167	0.975276180183917	ARID4A	1
GO:0007338	single fertilization	5/1068	153/18722	0.941152439410353	0.975688484737418	CD9/LHFPL2/GNPDA1/ABHD2/UBE3A	5
GO:0007605	sensory perception of sound	5/1068	154/18722	0.943239730536024	0.977110402384469	GPX1/MBP/OTOA/SCARB2/SLC1A3	5
GO:0006282	regulation of DNA repair	4/1068	130/18722	0.943255538485368	0.977110402384469	ACTR2/PARP9/WAS/DTX3L	4
GO:0006352	DNA-templated transcription, initiation	4/1068	130/18722	0.943255538485368	0.977110402384469	JUN/MITF/ERCC1/SETX	4
GO:0000959	mitochondrial RNA metabolic process	1/1068	49/18722	0.943972670057494	0.977110402384469	CHCHD10	1
GO:0007602	phototransduction	1/1068	49/18722	0.943972670057494	0.977110402384469	GNAQ	1
GO:0009994	oocyte differentiation	1/1068	49/18722	0.943972670057494	0.977110402384469	PTK2B	1
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1/1068	49/18722	0.943972670057494	0.977110402384469	FBXL15	1
GO:0051932	synaptic transmission, GABAergic	1/1068	49/18722	0.943972670057494	0.977110402384469	KIF5B	1
GO:0000723	telomere maintenance	4/1068	131/18722	0.945428495694744	0.978429643799163	SP100/ERCC1/ATM/NOP10	4
GO:0021766	hippocampus development	2/1068	80/18722	0.947176382690659	0.979487903880197	BTG2/KIF5B	2
GO:0032204	regulation of telomere maintenance	2/1068	80/18722	0.947176382690659	0.979487903880197	ERCC1/ATM	2
GO:0045814	negative regulation of gene expression, epigenetic	1/1068	50/18722	0.947177146487559	0.979487903880197	SPI1	1
GO:0090102	cochlea development	1/1068	50/18722	0.947177146487559	0.979487903880197	ADAM10	1
GO:0000280	nuclear division	18/1068	439/18722	0.947671316232995	0.979811155852316	DUSP1/RB1/ACTR2/ACTR3/FLNA/RHOA/HSPA1A/KLHDC8B/IL1B/RGCC/ATM/PRKAR1A/APC/NUP62/DYNC1LI1/CDC42/KPNB1/CHMP1B	18
GO:0008589	regulation of smoothened signaling pathway	2/1068	81/18722	0.949683997503121	0.980732810517713	RB1/PRKACB	2
GO:0010833	telomere maintenance via telomere lengthening	2/1068	81/18722	0.949683997503121	0.980732810517713	ATM/NOP10	2
GO:0014032	neural crest cell development	2/1068	81/18722	0.949683997503121	0.980732810517713	HIF1A/CORO1C	2
GO:0009584	detection of visible light	1/1068	51/18722	0.950198505075353	0.980732810517713	GNAQ	1
GO:0009948	anterior/posterior axis specification	1/1068	51/18722	0.950198505075353	0.980732810517713	SKI	1
GO:0045668	negative regulation of osteoblast differentiation	1/1068	51/18722	0.950198505075353	0.980732810517713	SKI	1
GO:0050982	detection of mechanical stimulus	1/1068	51/18722	0.950198505075353	0.980732810517713	CXCR4	1
GO:0060632	regulation of microtubule-based movement	1/1068	51/18722	0.950198505075353	0.980732810517713	LAMP1	1
GO:0065002	intracellular protein transmembrane transport	1/1068	51/18722	0.950198505075353	0.980732810517713	TRAM1	1
GO:0071826	ribonucleoprotein complex subunit organization	8/1068	227/18722	0.950405796569834	0.980759165861699	CELF2/SCAF11/RPS27L/ATM/ADAR/SETX/EIF2S3/KIF5B	8
GO:0060271	cilium assembly	13/1068	337/18722	0.951395217941705	0.981592465776948	SNX10/CCDC88A/ACTR2/ACTR3/FLNA/ATP6V0D1/EHD4/RILPL2/GSN/ATG3/CEP350/SDCCAG8/RAB8A	13
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	2/1068	82/18722	0.95207776510991	0.981921181294548	RNASET2/RNASE1	2
GO:2001252	positive regulation of chromosome organization	2/1068	82/18722	0.95207776510991	0.981921181294548	ERCC1/ATM	2
GO:0061053	somite development	2/1068	83/18722	0.954362498523768	0.984089440480461	LFNG/ABI1	2
GO:0007051	spindle organization	6/1068	184/18722	0.954854006457996	0.984408142691507	FLNA/RHOA/HSPA1A/NUP62/KPNB1/CHMP1B	6
GO:0032210	regulation of telomere maintenance via telomerase	1/1068	53/18722	0.955733091979668	0.984905269404581	ATM	1
GO:0051438	regulation of ubiquitin-protein transferase activity	1/1068	53/18722	0.955733091979668	0.984905269404581	DTX3L	1
GO:0006112	energy reserve metabolic process	2/1068	84/18722	0.956542832758296	0.984905269404581	PRKAG2/GAA	2
GO:0006405	RNA export from nucleus	2/1068	84/18722	0.956542832758296	0.984905269404581	NUP214/NUP62	2
GO:0006835	dicarboxylic acid transport	2/1068	84/18722	0.956542832758296	0.984905269404581	LRRC8C/SLC1A3	2
GO:0009953	dorsal/ventral pattern formation	2/1068	84/18722	0.956542832758296	0.984905269404581	FBXL15/PRKACB	2
GO:0022412	cellular process involved in reproduction in multicellular organism	15/1068	384/18722	0.956613883793441	0.984905269404581	CD9/ARRB2/RETN/CIB1/ZMIZ1/PRDM1/ABHD2/PTK2B/ERCC1/FNDC3A/QKI/ETV6/PRKAR1A/TGFBR1/BAX	15
GO:0014888	striated muscle adaptation	1/1068	54/18722	0.958265474954959	0.986225895938074	GSN	1
GO:0000724	double-strand break repair via homologous recombination	4/1068	138/18722	0.958627654595107	0.986225895938074	SAMHD1/ACTR2/WAS/RECQL	4
GO:0035107	appendage morphogenesis	4/1068	138/18722	0.958627654595107	0.986225895938074	MBNL1/NOTCH2/SKI/BAX	4
GO:0035108	limb morphogenesis	4/1068	138/18722	0.958627654595107	0.986225895938074	MBNL1/NOTCH2/SKI/BAX	4
GO:0033044	regulation of chromosome organization	6/1068	187/18722	0.959347498942917	0.986778327162787	DUSP1/RB1/ERCC1/ATM/APC/DYNC1LI1	6
GO:0006493	protein O-linked glycosylation	2/1068	86/18722	0.96060798154176	0.987180386776681	VEGFB/B3GNT2	2
GO:0009798	axis specification	2/1068	86/18722	0.96060798154176	0.987180386776681	NOTCH2/SKI	2
GO:0014031	mesenchymal cell development	2/1068	86/18722	0.96060798154176	0.987180386776681	HIF1A/CORO1C	2
GO:0006360	transcription by RNA polymerase I	1/1068	55/18722	0.960653115449286	0.987180386776681	FLNA	1
GO:0010676	positive regulation of cellular carbohydrate metabolic process	1/1068	55/18722	0.960653115449286	0.987180386776681	PTAFR	1
GO:0022904	respiratory electron transport chain	3/1068	114/18722	0.961519713779401	0.987882782854846	BID/SCO2/PLEC	3
GO:0000725	recombinational repair	4/1068	140/18722	0.961816880201598	0.987999978215843	SAMHD1/ACTR2/WAS/RECQL	4
GO:0001658	branching involved in ureteric bud morphogenesis	1/1068	56/18722	0.962904279144586	0.988552414433826	VEGFA	1
GO:0042733	embryonic digit morphogenesis	1/1068	56/18722	0.962904279144586	0.988552414433826	BAX	1
GO:0070534	protein K63-linked ubiquitination	1/1068	56/18722	0.962904279144586	0.988552414433826	RNF135	1
GO:0009451	RNA modification	5/1068	167/18722	0.964901887463466	0.990166266895535	APOBEC3C/APOBEC3A/TRMT1/ADAR/NOP10	5
GO:0010257	NADH dehydrogenase complex assembly	1/1068	57/18722	0.965026760119277	0.990166266895535	OXA1L	1
GO:0032981	mitochondrial respiratory chain complex I assembly	1/1068	57/18722	0.965026760119277	0.990166266895535	OXA1L	1
GO:0007131	reciprocal meiotic recombination	1/1068	58/18722	0.967027907732061	0.991842347485688	ATM	1
GO:0140527	reciprocal homologous recombination	1/1068	58/18722	0.967027907732061	0.991842347485688	ATM	1
GO:0035278	miRNA mediated inhibition of translation	2/1068	90/18722	0.967670761948232	0.991936062209851	ZFP36/STAT3	2
GO:0040033	negative regulation of translation, ncRNA-mediated	2/1068	90/18722	0.967670761948232	0.991936062209851	ZFP36/STAT3	2
GO:0048477	oogenesis	2/1068	90/18722	0.967670761948232	0.991936062209851	PTK2B/ERCC1	2
GO:0006406	mRNA export from nucleus	1/1068	59/18722	0.968914651974569	0.992597846146978	NUP214	1
GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus	1/1068	59/18722	0.968914651974569	0.992597846146978	NUP214	1
GO:0010906	regulation of glucose metabolic process	3/1068	119/18722	0.969142769485893	0.992597846146978	FBP1/PDK4/RANBP2	3
GO:0006354	DNA-templated transcription, elongation	2/1068	91/18722	0.969236110331436	0.992597846146978	ELL2/ZMIZ1	2
GO:0045974	regulation of translation, ncRNA-mediated	2/1068	91/18722	0.969236110331436	0.992597846146978	ZFP36/STAT3	2
GO:0022618	ribonucleoprotein complex assembly	7/1068	220/18722	0.970655636916819	0.993371869327822	CELF2/SCAF11/RPS27L/ATM/ADAR/SETX/EIF2S3	7
GO:0006289	nucleotide-excision repair	1/1068	60/18722	0.970693527379978	0.993371869327822	ERCC1	1
GO:0035825	homologous recombination	1/1068	60/18722	0.970693527379978	0.993371869327822	ATM	1
GO:0006497	protein lipidation	2/1068	92/18722	0.970728292617792	0.993371869327822	GLUL/ABCA1	2
GO:0048515	spermatid differentiation	5/1068	172/18722	0.970977971494609	0.993438971214431	CIB1/ABHD2/FNDC3A/QKI/BAX	5
GO:0033108	mitochondrial respiratory chain complex assembly	2/1068	93/18722	0.972150552266554	0.993600548254855	SCO2/OXA1L	2
GO:0045132	meiotic chromosome segregation	2/1068	93/18722	0.972150552266554	0.993600548254855	ACTR2/ACTR3	2
GO:0042255	ribosome assembly	1/1068	61/18722	0.972370695569786	0.993600548254855	RPS27L	1
GO:0043966	histone H3 acetylation	1/1068	61/18722	0.972370695569786	0.993600548254855	SPI1	1
GO:1904356	regulation of telomere maintenance via telomere lengthening	1/1068	61/18722	0.972370695569786	0.993600548254855	ATM	1
GO:1905515	non-motile cilium assembly	1/1068	61/18722	0.972370695569786	0.993600548254855	CEP350	1
GO:0002181	cytoplasmic translation	4/1068	148/18722	0.972424850877296	0.993600548254855	EIF2S3/ZNF385A/PKM/CNBP	4
GO:0048704	embryonic skeletal system morphogenesis	2/1068	94/18722	0.973506001226241	0.994407722104359	TGFBR2/TGFBR1	2
GO:0007062	sister chromatid cohesion	1/1068	62/18722	0.973951966516223	0.994407722104359	RB1	1
GO:0060113	inner ear receptor cell differentiation	1/1068	62/18722	0.973951966516223	0.994407722104359	SLC4A7	1
GO:0060675	ureteric bud morphogenesis	1/1068	62/18722	0.973951966516223	0.994407722104359	VEGFA	1
GO:0072171	mesonephric tubule morphogenesis	1/1068	63/18722	0.97544281859343	0.995741477323145	VEGFA	1
GO:0090501	RNA phosphodiester bond hydrolysis	4/1068	152/18722	0.976627631237806	0.996610712943112	RNASET2/SAMHD1/RNASE6/RNASE1	4
GO:0030858	positive regulation of epithelial cell differentiation	1/1068	64/18722	0.976848417486308	0.996610712943112	BTG1	1
GO:0045995	regulation of embryonic development	1/1068	64/18722	0.976848417486308	0.996610712943112	CFL1	1
GO:0035270	endocrine system development	3/1068	127/18722	0.978445284474399	0.99805118242417	TSPO/IL6R/TGFBR1	3
GO:0044782	cilium organization	13/1068	368/18722	0.97926154353211	0.998293697975083	SNX10/CCDC88A/ACTR2/ACTR3/FLNA/ATP6V0D1/EHD4/RILPL2/GSN/ATG3/CEP350/SDCCAG8/RAB8A	13
GO:0015837	amine transport	2/1068	99/18722	0.979381349910712	0.998293697975083	AQP9/RGS2	2
GO:0021549	cerebellum development	2/1068	99/18722	0.979381349910712	0.998293697975083	AIF1/PAK1	2
GO:2000272	negative regulation of signaling receptor activity	1/1068	66/18722	0.979423060985932	0.998293697975083	LILRB4	1
GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	1/1068	67/18722	0.980601028978376	0.998709362642511	CCR1	1
GO:0009583	detection of light stimulus	1/1068	67/18722	0.980601028978376	0.998709362642511	GNAQ	1
GO:0042490	mechanoreceptor differentiation	1/1068	67/18722	0.980601028978376	0.998709362642511	SLC4A7	1
GO:0043967	histone H4 acetylation	1/1068	67/18722	0.980601028978376	0.998709362642511	SPI1	1
GO:0090596	sensory organ morphogenesis	8/1068	256/18722	0.980756284774401	0.998709362642511	MAFB/HIF1A/VEGFA/PRDM1/NOTCH2/STAT3/SKI/BAX	8
GO:0032200	telomere organization	4/1068	159/18722	0.982569029266191	0.999999999998341	SP100/ERCC1/ATM/NOP10	4
GO:0031060	regulation of histone methylation	1/1068	69/18722	0.982758688399218	0.999999999998341	KMT2E	1
GO:0006997	nucleus organization	3/1068	133/18722	0.983598038712262	0.999999999998341	RTN4/PLEC/CHMP1B	3
GO:0048839	inner ear development	5/1068	188/18722	0.9844778508903	0.999999999998341	MAFB/SLC4A7/MAF/CEBPA/ADAM10	5
GO:0072078	nephron tubule morphogenesis	1/1068	71/18722	0.984676560725339	0.999999999998341	VEGFA	1
GO:0009581	detection of external stimulus	3/1068	135/18722	0.985036628937112	0.999999999998341	CXCR4/ARRB2/GNAQ	3
GO:0042273	ribosomal large subunit biogenesis	1/1068	72/18722	0.985554016794469	0.999999999998341	GTF3A	1
GO:0007018	microtubule-based movement	13/1068	382/18722	0.986228790979265	0.999999999998341	HIF1A/ACTR2/ACTR3/PLTP/BLOC1S1/BLOC1S2/ARL8B/LAMP1/DYNC1LI1/CDC42/KTN1/KIF5B/KPNB1	13
GO:0042274	ribosomal small subunit biogenesis	1/1068	73/18722	0.986381272025756	0.999999999998341	RPS27L	1
GO:0051937	catecholamine transport	1/1068	73/18722	0.986381272025756	0.999999999998341	ACTB	1
GO:0007286	spermatid development	4/1068	165/18722	0.98649450485091	0.999999999998341	CIB1/ABHD2/FNDC3A/QKI	4
GO:0022037	metencephalon development	2/1068	108/18722	0.986933258170218	0.999999999998341	AIF1/PAK1	2
GO:0007224	smoothened signaling pathway	3/1068	138/18722	0.986969965680989	0.999999999998341	RB1/TGFBR2/PRKACB	3
GO:0009582	detection of abiotic stimulus	3/1068	138/18722	0.986969965680989	0.999999999998341	CXCR4/ARRB2/GNAQ	3
GO:0016579	protein deubiquitination	3/1068	139/18722	0.987559335269844	0.999999999998341	OTUD1/TNFAIP3/USP3	3
GO:0071426	ribonucleoprotein complex export from nucleus	1/1068	76/18722	0.988589718058439	0.999999999998341	NUP214	1
GO:0006367	transcription initiation from RNA polymerase II promoter	1/1068	77/18722	0.989243272767953	0.999999999998341	ERCC1	1
GO:0031016	pancreas development	1/1068	77/18722	0.989243272767953	0.999999999998341	IL6R	1
GO:0071166	ribonucleoprotein complex localization	1/1068	77/18722	0.989243272767953	0.999999999998341	NUP214	1
GO:0048736	appendage development	4/1068	172/18722	0.990012494270397	0.999999999998341	MBNL1/NOTCH2/SKI/BAX	4
GO:0060173	limb development	4/1068	172/18722	0.990012494270397	0.999999999998341	MBNL1/NOTCH2/SKI/BAX	4
GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	1/1068	79/18722	0.990440317453788	0.999999999998341	RNASE6	1
GO:0006473	protein acetylation	5/1068	201/18722	0.990828768259271	0.999999999998341	NUPR1/SPI1/BLOC1S1/IL1B/TAOK1	5
GO:0034968	histone lysine methylation	2/1068	115/18722	0.99087091049339	0.999999999998341	KMT2E/ARID4A	2
GO:0007281	germ cell development	8/1068	278/18722	0.991084727472417	0.999999999998341	CIB1/PRDM1/ABHD2/PTK2B/ERCC1/FNDC3A/QKI/BAX	8
GO:1903046	meiotic cell cycle process	5/1068	202/18722	0.991197894204068	0.999999999998341	ACTR2/ACTR3/ERCC1/ATM/PRKAR1A	5
GO:0031123	RNA 3'-end processing	2/1068	116/18722	0.991328990419324	0.999999999998341	ZFP36L1/PABPC1	2
GO:0001942	hair follicle development	1/1068	81/18722	0.991504261756306	0.999999999998341	HPSE	1
GO:0018205	peptidyl-lysine modification	12/1068	376/18722	0.991822110578352	0.999999999998341	SPI1/ZMIZ1/BLOC1S1/IFIH1/KMT2E/IL1B/SUMO3/ARID4A/PIAS1/RANBP2/EGR1/SUMO2	12
GO:0008543	fibroblast growth factor receptor signaling pathway	1/1068	82/18722	0.991991008628484	0.999999999998341	SETX	1
GO:0001510	RNA methylation	1/1068	83/18722	0.992449892898054	0.999999999998341	TRMT1	1
GO:0022404	molting cycle process	1/1068	84/18722	0.99288250808046	0.999999999998341	HPSE	1
GO:0022405	hair cycle process	1/1068	84/18722	0.99288250808046	0.999999999998341	HPSE	1
GO:0048562	embryonic organ morphogenesis	8/1068	285/18722	0.99307783379732	0.999999999998341	MAFB/ID2/HIF1A/MEF2C/ENG/TGFBR2/NOTCH2/TGFBR1	8
GO:0006479	protein methylation	4/1068	181/18722	0.993264855094755	0.999999999998341	KMT2E/BTG2/BTG1/ARID4A	4
GO:0008213	protein alkylation	4/1068	181/18722	0.993264855094755	0.999999999998341	KMT2E/BTG2/BTG1/ARID4A	4
GO:0098773	skin epidermis development	1/1068	85/18722	0.993290356635566	0.999999999998341	HPSE	1
GO:0048706	embryonic skeletal system development	2/1068	121/18722	0.993302760756271	0.999999999998341	TGFBR2/TGFBR1	2
GO:0051321	meiotic cell cycle	7/1068	261/18722	0.99335670272744	0.999999999998341	DUSP1/ACTR2/ACTR3/ERCC1/ATM/PRKAR1A/PRKACB	7
GO:0008380	RNA splicing	14/1068	434/18722	0.994318428950565	0.999999999998341	LGALS3/MBNL1/YBX1/TMBIM6/HSPA1A/CELF2/PABPC1/SCAF11/QKI/SETX/DDX5/IVNS1ABP/PTBP3/PIK3R1	14
GO:0140013	meiotic nuclear division	4/1068	185/18722	0.994358267916239	0.999999999998341	ACTR2/ACTR3/ATM/PRKAR1A	4
GO:0043583	ear development	5/1068	213/18722	0.994427808037399	0.999999999998341	MAFB/SLC4A7/MAF/CEBPA/ADAM10	5
GO:0070646	protein modification by small protein removal	3/1068	157/18722	0.994664273459562	0.999999999998341	OTUD1/TNFAIP3/USP3	3
GO:0006400	tRNA modification	1/1068	90/18722	0.995004942900301	0.999999999998341	TRMT1	1
GO:0043543	protein acylation	6/1068	243/18722	0.995120121629608	0.999999999998341	GLUL/NUPR1/SPI1/BLOC1S1/IL1B/TAOK1	6
GO:0001657	ureteric bud development	1/1068	91/18722	0.995291263262177	0.999999999998341	VEGFA	1
GO:0051952	regulation of amine transport	1/1068	91/18722	0.995291263262177	0.999999999998341	RGS2	1
GO:0001708	cell fate specification	1/1068	92/18722	0.995561186016511	0.999999999998341	APC	1
GO:0072163	mesonephric epithelium development	1/1068	92/18722	0.995561186016511	0.999999999998341	VEGFA	1
GO:0072164	mesonephric tubule development	1/1068	92/18722	0.995561186016511	0.999999999998341	VEGFA	1
GO:0018022	peptidyl-lysine methylation	2/1068	131/18722	0.996021142906972	0.999999999998341	KMT2E/ARID4A	2
GO:0042773	ATP synthesis coupled electron transport	1/1068	95/18722	0.996281686135786	0.999999999998341	BID	1
GO:0042775	mitochondrial ATP synthesis coupled electron transport	1/1068	95/18722	0.996281686135786	0.999999999998341	BID	1
GO:0001823	mesonephros development	1/1068	96/18722	0.996494879844219	0.999999999998341	VEGFA	1
GO:0042472	inner ear morphogenesis	1/1068	96/18722	0.996494879844219	0.999999999998341	MAFB	1
GO:0061982	meiosis I cell cycle process	2/1068	135/18722	0.996773818566999	0.999999999998341	ERCC1/ATM	2
GO:0018394	peptidyl-lysine acetylation	3/1068	169/18722	0.997003386204988	0.999999999998341	SPI1/BLOC1S1/IL1B	3
GO:0006338	chromatin remodeling	6/1068	255/18722	0.997004344597827	0.999999999998341	ACTB/RB1/BAZ2B/BAZ1A/PAK1/CHD4	6
GO:0021510	spinal cord development	1/1068	99/18722	0.997063939548313	0.999999999998341	PBX3	1
GO:0016571	histone methylation	2/1068	141/18722	0.997647773620976	0.999999999998341	KMT2E/ARID4A	2
GO:0016570	histone modification	14/1068	463/18722	0.997744695343501	0.999999999998341	SPI1/VEGFA/DTX3L/JDP2/JAK2/BCL6/LRRK2/KMT2E/IL1B/JMJD1C/ARID4A/ATM/USP3/SKI	14
GO:0007218	neuropeptide signaling pathway	1/1068	106/18722	0.998058249050953	0.999999999998341	SORL1	1
GO:0042303	molting cycle	1/1068	107/18722	0.998169647311245	0.999999999998341	HPSE	1
GO:0042633	hair cycle	1/1068	107/18722	0.998169647311245	0.999999999998341	HPSE	1
GO:0140053	mitochondrial gene expression	1/1068	108/18722	0.998274660293871	0.999999999998341	CHCHD10	1
GO:0030317	flagellated sperm motility	1/1068	110/18722	0.998466972209591	0.999999999998341	PLTP	1
GO:0097722	sperm motility	1/1068	110/18722	0.998466972209591	0.999999999998341	PLTP	1
GO:0007601	visual perception	4/1068	215/18722	0.998557580936166	0.999999999998341	TGFBI/PPT1/DRAM2/DHRS3	4
GO:0016573	histone acetylation	2/1068	152/18722	0.998687223936431	0.999999999998341	SPI1/IL1B	2
GO:0050953	sensory perception of light stimulus	4/1068	219/18722	0.998802485235856	0.999999999998341	TGFBI/PPT1/DRAM2/DHRS3	4
GO:0006325	chromatin organization	11/1068	409/18722	0.998834293354778	0.999999999998341	ACTB/RB1/CHD9/IKZF1/GPX4/KMT2E/BAZ2B/BAZ1A/PAK1/NR3C1/CHD4	11
GO:0042471	ear morphogenesis	1/1068	115/18722	0.998859189014349	0.999999999998341	MAFB	1
GO:0018393	internal peptidyl-lysine acetylation	2/1068	158/18722	0.999046843508615	0.999999999998341	SPI1/IL1B	2
GO:0032259	methylation	9/1068	364/18722	0.999073899174109	0.999999999998341	FOS/SPI1/HNMT/PRDM1/KMT2E/BTG2/BTG1/TRMT1/ARID4A	9
GO:0006475	internal protein amino acid acetylation	2/1068	160/18722	0.999143564190505	0.999999999998341	SPI1/IL1B	2
GO:0043414	macromolecule methylation	7/1068	316/18722	0.999257499883943	0.999999999998341	FOS/SPI1/KMT2E/BTG2/BTG1/TRMT1/ARID4A	7
GO:0060294	cilium movement involved in cell motility	1/1068	125/18722	0.999368411200055	0.999999999998341	PLTP	1
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	7/1068	320/18722	0.999371449896597	0.999999999998341	MBNL1/CELF2/PABPC1/SCAF11/QKI/SETX/DDX5	7
GO:0000398	mRNA splicing, via spliceosome	7/1068	320/18722	0.999371449896597	0.999999999998341	MBNL1/CELF2/PABPC1/SCAF11/QKI/SETX/DDX5	7
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	2/1068	167/18722	0.999411730815211	0.999999999998341	CD84/PECAM1	2
GO:0008033	tRNA processing	1/1068	127/18722	0.999438872572787	0.999999999998341	TRMT1	1
GO:0000375	RNA splicing, via transesterification reactions	7/1068	324/18722	0.99946837549689	0.999999999998341	MBNL1/CELF2/PABPC1/SCAF11/QKI/SETX/DDX5	7
GO:0007127	meiosis I	1/1068	129/18722	0.999501479660973	0.999999999998341	ATM	1
GO:0001539	cilium or flagellum-dependent cell motility	1/1068	138/18722	0.99970730949309	0.999999999998341	PLTP	1
GO:0060285	cilium-dependent cell motility	1/1068	138/18722	0.99970730949309	0.999999999998341	PLTP	1
GO:0065004	protein-DNA complex assembly	2/1068	201/18722	0.999907087891704	0.999999999998341	RB1/PIAS1	2
GO:0022613	ribonucleoprotein complex biogenesis	10/1068	463/18722	0.999948089238696	0.999999999998341	GLUL/CELF2/SCAF11/RPS27L/ATM/ADAR/SETX/GTF3A/NOP10/EIF2S3	10
GO:0071103	DNA conformation change	4/1068	290/18722	0.999961242571772	0.999999999998341	CHD9/RECQL/SETX/CHD4	4
GO:0003341	cilium movement	1/1068	175/18722	0.999967311066819	0.999999999998341	PLTP	1
GO:0006399	tRNA metabolic process	1/1068	179/18722	0.99997421519785	0.999999999998341	TRMT1	1
GO:0042254	ribosome biogenesis	4/1068	299/18722	0.999975268096455	0.999999999998341	GLUL/RPS27L/GTF3A/NOP10	4
GO:0071824	protein-DNA complex subunit organization	2/1068	241/18722	0.999989779368121	0.999999999998341	RB1/PIAS1	2
GO:0006364	rRNA processing	1/1068	225/18722	0.999998322006122	0.999999999998341	NOP10	1
GO:0016072	rRNA metabolic process	1/1068	236/18722	0.999999127844112	0.999999999998341	NOP10	1
GO:0034470	ncRNA processing	4/1068	395/18722	0.999999822416586	0.999999999998341	STAT3/TRMT1/ADAR/NOP10	4
GO:0034660	ncRNA metabolic process	4/1068	485/18722	0.999999998551262	0.999999999998341	STAT3/TRMT1/ADAR/NOP10	4
GO:0007608	sensory perception of smell	1/1068	456/18722	0.999999999998341	0.999999999998341	B3GNT2	1