ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	Count
GO:0002764	immune response-regulating signaling pathway	89/896	468/18722	8.30173920894194e-30	4.3177345625707e-26	FCN1/CTSS/MNDA/TYROBP/CYBA/FCER1G/CD14/PTPRC/HLA-A/LAPTM5/NFKBIA/FPR1/IRF1/C5AR1/NFKBIZ/CLEC7A/HLA-DPB1/LYN/CD36/FGR/HLA-DRB1/TNFAIP3/GBP1/LILRB2/HCK/ARRB2/SCIMP/IRAK3/CLEC4E/HLA-DQB1/USP15/MEF2C/THEMIS2/PTPN6/LILRB1/CTSH/PRKCB/LY96/TLR2/MAP3K1/NCKAP1L/SYK/MYO1G/PIK3AP1/PLSCR1/LAT2/PRAM1/TLR8/CSK/LCP2/OAS1/LILRA2/MYD88/FCGR1B/TLR4/CD33/CD300LF/NFAM1/BIRC3/FYN/IRF7/CD300A/INPP5D/TLR1/BTK/MAPKAPK3/HSPA1A/UNC93B1/IFI35/CMTM3/RAP1A/PAK1/RPS6KA3/PAK2/CYLD/MAPK1/DGKZ/IFIH1/SEC14L1/PJA2/PTPN2/NMI/DDX3X/PRNP/CREBBP/EP300/NINJ1/WNK1/BIRC2	89
GO:0001819	positive regulation of cytokine production	87/896	467/18722	1.79339755080442e-28	4.66373033086688e-25	FCN1/MNDA/AIF1/TYROBP/IL1B/CYBB/CYBA/FCER1G/CD14/PTPRC/HLA-A/LAPTM5/CD74/PYCARD/HLA-DPA1/CCL3/POU2F2/IRF1/B2M/C5AR1/LRRK2/CLEC7A/HLA-DPB1/SLC11A1/EGR1/IFI16/CD36/FGR/ISG15/CASP1/PTGS2/HLA-E/STAT1/LILRB2/GPSM3/CYP1B1/SCIMP/IRAK3/CD83/CEBPB/IL17RA/LILRB1/JAK2/LGALS9/HLA-F/LY96/TLR2/GBP5/CD4/TGFB1/SYK/CD86/NLRP3/CCR2/SORL1/TLR8/CSF1R/SULF2/LILRA5/OAS1/OAS2/LILRA2/TNF/MYD88/TNFRSF14/IL6R/TLR4/NFAM1/PTAFR/MBP/IRF7/SPN/TLR1/IRF8/HSPA1A/CD84/IFNGR1/STAT3/HIF1A/CARD8/ATP6AP2/IFIH1/HMOX1/ADAM17/DDX21/DDX3X/CREB1	87
GO:0019221	cytokine-mediated signaling pathway	86/896	472/18722	1.94489632832895e-27	3.37180193454628e-24	IL1B/FCER1G/TMSB4X/PTPRC/CCL3L3/LAPTM5/SAMHD1/CD74/PYCARD/IFITM3/NFKBIA/CD44/TNFSF13B/CARD16/TNFRSF1B/CCL3/IRF1/SPI1/EGR1/ISG15/CASP1/TNFAIP3/STAT1/LILRB3/LILRB2/HCK/IRAK3/CXCL8/PLP2/IFNGR2/PTPN6/IL17RA/MX1/LILRB1/IFITM2/JAK2/CX3CR1/CCR1/IL1RN/IL10RA/CD4/SYK/CCR2/STAT2/CSF1R/CXCR4/LILRA5/OAS1/OAS2/LILRA2/TNF/MYD88/TNFRSF14/STAT6/IL6R/PARP9/CD300LF/BIRC3/IRF7/CCL4/SH2B3/ACSL1/PTK2B/JAK1/HSPA1A/IL13RA1/PARP14/SP100/CSF2RB/IFNGR1/PRKACA/STAT3/TNFRSF1A/CYLD/LIMS1/HIF1A/CARD8/ADAR/PTPN2/HIPK1/ADAM17/NMI/WNK1/IFNAR1/BIRC2/CIB1	86
GO:0042110	T cell activation	87/896	487/18722	4.10155914513882e-27	5.26084041058646e-24	AIF1/FGL2/IL1B/FCER1G/LCP1/PTPRC/HLA-A/LAPTM5/ZFP36L2/HLA-DRA/CD74/PYCARD/CORO1A/LGALS1/CD44/TNFSF13B/TNFRSF1B/CD48/HLA-DPA1/JAML/IRF1/B2M/SPI1/MSN/NFKBIZ/CLEC7A/HLA-DPB1/SLC11A1/EGR1/LYN/HLA-DRB1/HLA-E/LILRB2/MAFB/WAS/HLA-DQB1/HLA-DMA/HLA-DMB/RAC2/CD83/CEBPB/PTPN6/LILRB1/LGALS9/CLEC4A/ITGAL/CD4/NCKAP1L/SYK/DOCK2/CD86/NLRP3/CCR2/CSK/LFNG/APBB1IP/TNFRSF14/TCIRG1/STAT6/RHOA/IL6R/RAB27A/HLA-DQA1/FYN/CD300A/SPN/PAG1/BCL6/TNFAIP8L2/PREX1/ZFP36L1/FKBP1A/CD84/PSMB10/PRKAR1A/DOCK8/STAT3/SIRPA/AZI2/MAP3K8/TGFBR2/MYH9/PPP3CA/PTPN2/ADAM17/PRNP/SP3	87
GO:0002274	myeloid leukocyte activation	58/896	223/18722	5.05752779329596e-27	5.26084041058646e-24	AIF1/TYROBP/FCER1G/ITGB2/PTPRC/S100A12/CD74/PYCARD/NAMPT/CCL3/STXBP2/SPI1/C5AR1/LRRK2/SLC11A1/LYN/FGR/CXCL8/RAC2/IFNGR2/JAK2/CX3CR1/LGALS9/CD93/GRN/TLR2/SYK/DOCK2/NOTCH2/PLSCR1/CCR2/LAT2/PRAM1/LCP2/LILRA2/TNF/MYD88/ITGAM/TLR4/CD33/CD300LF/ADGRE2/PTAFR/CD300A/TLR1/BTK/PREX1/IFI35/JUND/CD84/IFNGR1/KMT2E/ADAM10/PJA2/HMOX1/TGFBR2/LTBR/NMI	58
GO:0002683	negative regulation of immune system process	80/896	434/18722	6.45685731423807e-26	5.5970191485587e-23	MNDA/FGL2/LST1/TYROBP/DUSP1/HLA-B/PTPRC/HLA-A/LAPTM5/SAMHD1/CD74/CCL3/IRF1/TSC22D3/SPI1/LYN/IFI16/FGR/ISG15/HLA-DRB1/TNFAIP3/GBP1/HLA-E/LILRB3/BST2/LILRB2/HCK/MAFB/CD68/ARRB2/IRAK3/TMEM176B/USP15/CEBPB/PTPN6/LILRB1/GPX1/CX3CR1/LGALS9/GRN/HLA-F/NCKAP1L/TGFB1/SYK/CD86/CCR2/STAT2/OAS1/TNF/TNFRSF14/STAT6/TLR4/TMEM176A/RIN3/CD300LF/FYN/CD300A/SPN/PAG1/INPP5D/BCL6/TNFAIP8L2/BTK/SAMSN1/AHR/PARP14/TRIB1/PKN1/CD84/PRKAR1A/DGKZ/ADAR/ATM/PCBP2/SEC14L1/HMOX1/PTPN2/TMBIM6/NMI/PRNP	80
GO:0002366	leukocyte activation involved in immune response	62/896	275/18722	3.86143918194592e-25	2.86904931218582e-22	FGL2/TYROBP/FCER1G/LCP1/ITGB2/PTPRC/HLA-DRA/CD74/PYCARD/CORO1A/LGALS1/CCL3/STXBP2/SPI1/NFKBIZ/CLEC7A/SLC11A1/LYN/FGR/HLA-DRB1/HLA-DMB/RAC2/LILRB1/CX3CR1/LGALS9/GRN/HLA-F/ITGAL/NCKAP1L/TGFB1/SYK/DOCK2/NOTCH2/CD86/NLRP3/CCR2/LAT2/PRAM1/LFNG/APBB1IP/LILRA2/MYD88/STAT6/ITGAM/IL6R/TLR4/GAPT/RAB27A/ADGRE2/PTAFR/DOCK11/CD300A/SPN/BCL6/BTK/IRF8/PTK2B/IFI35/CD84/STAT3/HMOX1/NMI	62
GO:0007159	leukocyte cell-cell adhesion	72/896	371/18722	8.35052776198311e-25	4.60568764207195e-22	S100A9/S100A8/AIF1/FGL2/IL1B/ITGB2/PTPRC/HLA-A/LAPTM5/HLA-DRA/CD74/PYCARD/CORO1A/LGALS1/CD44/TNFSF13B/HLA-DPA1/IRF1/B2M/MSN/NFKBIZ/HLA-DPB1/LYN/KLF4/SELL/HLA-DRB1/HLA-E/LILRB2/HLA-DQB1/HLA-DMA/HLA-DMB/RAC2/CD83/PECAM1/ITGA4/CEBPB/PTPN6/LILRB1/CX3CR1/LGALS9/ITGAL/FERMT3/CD4/NCKAP1L/SYK/CD86/NLRP3/CCR2/CSK/SELPLG/TNF/TNFRSF14/ALOX5/RHOA/PTAFR/HLA-DQA1/FYN/CD300A/SPN/PAG1/BCL6/TNFAIP8L2/STK10/PRKAR1A/DOCK8/SIRPA/ROCK1/MAP3K8/TGFBR2/PTPN2/PRNP/WNK1	72
GO:0030099	myeloid cell differentiation	73/896	381/18722	8.80357786449328e-25	4.60568764207195e-22	TYROBP/FOS/ZFP36/JUNB/EVI2B/CD74/NFKBIA/KLF2/CCL3/B2M/SPI1/LYN/IFI16/ISG15/HLA-DRB1/SNX10/STAT1/LILRB3/MAFB/MEF2C/CEBPB/PTPN6/LILRB1/JAK2/CCR1/TLR2/CD4/NCKAP1L/TGFB1/NOTCH2/OSCAR/CSF1R/RASSF2/TNF/TCIRG1/FLI1/TLR4/IKZF1/IRF7/INPP5D/SH2B3/BCL6/IRF8/JUN/PTK2B/ZFP36L1/HSPA1A/HCLS1/TRIB1/G6PD/CDC42/KMT2E/PTBP3/STAT3/RB1/KLF10/HIF1A/ARID4A/ZNF385A/ADAR/ZBTB7A/TET2/PIP4K2A/TGFBR2/LBR/MYH9/PTPN2/LTBR/ABI1/EP300/SP3/CREB1/CIB1	73
GO:0002263	cell activation involved in immune response	62/896	279/18722	8.85538866001145e-25	4.60568764207195e-22	FGL2/TYROBP/FCER1G/LCP1/ITGB2/PTPRC/HLA-DRA/CD74/PYCARD/CORO1A/LGALS1/CCL3/STXBP2/SPI1/NFKBIZ/CLEC7A/SLC11A1/LYN/FGR/HLA-DRB1/HLA-DMB/RAC2/LILRB1/CX3CR1/LGALS9/GRN/HLA-F/ITGAL/NCKAP1L/TGFB1/SYK/DOCK2/NOTCH2/CD86/NLRP3/CCR2/LAT2/PRAM1/LFNG/APBB1IP/LILRA2/MYD88/STAT6/ITGAM/IL6R/TLR4/GAPT/RAB27A/ADGRE2/PTAFR/DOCK11/CD300A/SPN/BCL6/BTK/IRF8/PTK2B/IFI35/CD84/STAT3/HMOX1/NMI	62
GO:0032103	positive regulation of response to external stimulus	75/896	427/18722	5.21894937854427e-23	2.46761415616443e-20	FCN1/S100A9/MNDA/S100A8/AIF1/TYROBP/IL1B/CYBA/TMSB4X/S100A12/CD74/PYCARD/NFKBIA/NEAT1/CCL3/SPI1/C5AR1/LRRK2/NFKBIZ/CLEC7A/LYN/FLNA/IFI16/PTGS2/HLA-E/HCK/GPSM3/SCIMP/CXCL8/RAC2/USP15/CEBPB/IL17RA/JAK2/CX3CR1/CCR1/LGALS9/LY86/GRN/HLA-F/LY96/TLR2/GBP5/NCKAP1L/TGFB1/SYK/PLSCR1/CCR2/TLR8/CSF1R/CXCR4/LILRA5/LILRA2/TNF/IL6R/TLR4/PARP9/FYN/IRF7/CCL4/BTK/PTK2B/IFI35/ALOX5AP/PAK1/PAK2/TNFRSF1A/ADAM10/MAPK1/ADAM17/NMI/CREBBP/EP300/NINJ1/WNK1	75
GO:0050900	leukocyte migration	69/896	369/18722	7.69174922284341e-23	3.33373230900071e-20	S100A9/S100A8/AIF1/FCER1G/ITGB2/DUSP1/S100A12/CCL3L3/CD74/PYCARD/CORO1A/CCL3/JAML/SPI1/C5AR1/MSN/LYN/LYST/SELL/HCK/GPSM3/CXCL8/RAC2/PECAM1/ITGA4/CX3CR1/CCR1/LGALS9/ITGAL/NCKAP1L/SYK/MYO1G/NLRP3/CCR2/BST1/CSF1R/CXCR4/TREM1/SELPLG/TNF/MYD88/TNFRSF14/ALOX5/RHOA/IL6R/RIN3/ADGRE2/PTAFR/FYN/CD300A/SPN/CCL4/PREX1/PTK2B/RHOG/STK10/CKLF/CDC42/DOCK8/SIRPA/ROCK1/ADAM10/MAPK1/HMOX1/MYH9/ADAM17/PLEC/NINJ1/WNK1	69
GO:0032496	response to lipopolysaccharide	66/896	343/18722	1.33137557458831e-22	5.32652643341061e-20	S100A9/S100A8/IL1B/FOS/CD14/TSPO/ZFP36/VIM/PYCARD/SOD2/NFKBIA/CARD16/TNFRSF1B/CCL3/SPI1/C5AR1/SLC11A1/LYN/CD36/CASP1/PTGS2/TNFAIP3/LILRB2/HCK/CD68/SCIMP/IRAK3/MTDH/CXCL8/NR4A1/MEF2C/CEBPB/LILRB1/JAK2/CX3CR1/LGALS9/LY86/IL10RA/LY96/TLR2/TGFB1/CD86/NLRP3/LILRA2/TNF/MYD88/RHOA/TLR4/MGST1/PTAFR/GCH1/IRF8/JUN/MAPKAPK3/CAPN2/TRIB1/JUND/CSF2RB/LITAF/RPS6KA3/SIRPA/CARD8/MAPK1/ADAM17/NFKB1/IFNAR1	66
GO:0002237	response to molecule of bacterial origin	68/896	363/18722	1.43638001865418e-22	5.33615176930029e-20	S100A9/S100A8/IL1B/FOS/CD14/TSPO/ZFP36/VIM/PYCARD/SOD2/NFKBIA/CARD16/TNFRSF1B/CCL3/B2M/SPI1/C5AR1/SLC11A1/LYN/CD36/CASP1/PTGS2/TNFAIP3/LILRB2/HCK/CD68/SCIMP/IRAK3/MTDH/CXCL8/NR4A1/MEF2C/CEBPB/LILRB1/JAK2/CX3CR1/LGALS9/LY86/IL10RA/LY96/TLR2/TGFB1/CD86/NLRP3/LILRA2/TNF/MYD88/RHOA/TLR4/MGST1/PTAFR/GCH1/TLR1/IRF8/JUN/MAPKAPK3/CAPN2/TRIB1/JUND/CSF2RB/LITAF/RPS6KA3/SIRPA/CARD8/MAPK1/ADAM17/NFKB1/IFNAR1	68
GO:0002831	regulation of response to biotic stimulus	63/896	327/18722	1.18872049776454e-21	4.12169020591559e-19	FCN1/MNDA/FGL2/TYROBP/CYBA/NCF1/HLA-B/HLA-A/SAMHD1/PYCARD/CARD16/IRF1/SPI1/CLEC7A/LYN/IFI16/CD36/FGR/ISG15/HLA-DRB1/TNFAIP3/HLA-E/STAT1/HCK/ARRB2/SCIMP/IRAK3/USP15/PTPN6/LILRB1/LGALS9/LY86/GRN/HLA-F/LY96/GBP5/SYK/PLSCR1/STAT2/TLR8/OAS1/LILRA2/TLR4/PARP9/BIRC3/FYN/IRF7/AHR/PARP14/IFI35/TRIB1/DTX3L/PAK1/PAK2/CARD8/ADAR/PCBP2/SEC14L1/PTPN2/NMI/CREBBP/EP300/BIRC2	63
GO:0034341	response to interferon-gamma	41/896	141/18722	1.9503062525245e-21	6.33971426211244e-19	AIF1/VIM/CCL3L3/CD74/IFITM3/HLA-DPA1/CCL3/IRF1/SLC11A1/CASP1/GBP1/STAT1/BST2/HCK/ACTR2/WAS/GBP2/IFNGR2/IFITM2/JAK2/LGALS9/ZYX/TLR2/GBP4/GBP5/TLR4/PARP9/GCH1/CCL4/KYNU/IRF8/JAK1/PARP14/ACTR3/SP100/IFNGR1/CDC42/SIRPA/CALCOCO2/PTPN2/NMI	41
GO:0009615	response to virus	66/896	367/18722	6.21170627628287e-21	1.90041672605572e-18	FGL2/APOBEC3A/PTPRC/SAMHD1/PYCARD/IFITM3/POU2F2/IRF1/IFIT2/LYST/IFI16/FGR/ISG15/TNFAIP3/GBP1/STAT1/BST2/IRAK3/IFIT3/USP15/IFNGR2/IFI44L/IL17RA/MX1/LILRB1/NPC2/IFITM2/LGALS9/TLR2/TRIM22/MX2/RNASE6/PLSCR1/STAT2/TLR8/CXCR4/OAS1/OAS2/TNF/MYD88/IFI44/ITGAX/PARP9/BIRC3/IRF7/CCL4/UNC93B1/CFL1/DTX3L/IFNGR1/BNIP3L/IVNS1ABP/HIF1A/CARD8/IFIH1/IRF2/ADAR/PCBP2/SEC14L1/HNRNPUL1/NMI/DDX21/DDX3X/NFKB1/IFNAR1/BIRC2	66
GO:0070661	leukocyte proliferation	61/896	318/18722	6.74546896044783e-21	1.94906578129384e-18	MNDA/AIF1/LST1/TYROBP/IL1B/PTPRC/HLA-A/CD74/PYCARD/CORO1A/TNFSF13B/TNFRSF1B/HLA-DPA1/IRF1/MSN/HLA-DPB1/SLC11A1/LYN/HLA-DRB1/TNFAIP3/HLA-E/BST2/LILRB2/HLA-DMB/RAC2/MEF2C/CEBPB/PTPN6/LILRB1/LGALS9/NCKAP1L/SYK/DOCK2/CD86/CCR2/BST1/CSF1R/MYD88/TNFRSF14/TCIRG1/TLR4/GAPT/FYN/CD300A/HHEX/SPN/INPP5D/BCL6/BTK/AHR/PKN1/CDKN1A/PSMB10/PRKAR1A/DOCK8/MAPK1/ATM/AZI2/TGFBR2/IRS2/PRNP	61
GO:0071216	cellular response to biotic stimulus	53/896	246/18722	1.08973687772848e-20	2.98301131635044e-18	IL1B/TXNIP/CD14/TSPO/ZFP36/VIM/PYCARD/NFKBIA/CARD16/TNFRSF1B/CCL3/SPI1/CLEC7A/LYN/CD36/CASP1/TNFAIP3/LILRB2/HCK/CD68/SCIMP/MTDH/CXCL8/MEF2C/CEBPB/LILRB1/CX3CR1/LY86/LY96/TLR2/TGFB1/SYK/CD86/NLRP3/BID/LILRA2/TNF/MYD88/RHOA/TLR4/PTAFR/APAF1/TLR1/BTK/IRF8/CAPN2/TRIB1/LITAF/SIRPA/CARD8/MAPK1/PPP1R15B/NFKB1	53
GO:0019882	antigen processing and presentation	35/896	106/18722	1.66594121035627e-20	4.30692773477153e-18	CTSS/FGL2/FCER1G/HLA-B/HLA-C/HLA-A/HLA-DRA/CD74/PYCARD/HLA-DPA1/B2M/HLA-DPB1/SLC11A1/IFI30/HLA-DRB1/HLA-E/LILRB2/CD68/WAS/PSMB8/HLA-DQB1/HLA-DMA/HLA-DMB/RAB32/HLA-F/CTSH/CLEC4A/RAB27A/HLA-DQA1/TAP1/TAPBP/PSME1/RAB8B/LNPEP/RAB10	35
GO:1903131	mononuclear cell differentiation	71/896	426/18722	1.73900177716212e-20	4.30692773477153e-18	FGL2/IL1B/FCER1G/HLA-B/PTPRC/ZFP36L2/HLA-DRA/CD74/LGALS1/TNFSF13B/KLF6/IRF1/B2M/SPI1/NFKBIZ/EGR1/LYN/IFI16/HLA-DRB1/LILRB2/MAFB/TMEM176B/CD83/ITGA4/CEBPB/PTPN6/LILRB1/LGALS9/CD4/NCKAP1L/SYK/DOCK2/NOTCH2/CD86/NLRP3/CCR2/CSF1R/LFNG/TCIRG1/STAT6/RHOA/IL6R/TMEM176A/IKZF1/NFAM1/IRF7/DOCK11/HHEX/SPN/LYL1/INPP5D/BCL6/BTK/IRF8/PREX1/JUN/PTK2B/ZFP36L1/CMTM7/STAT3/ATM/AZI2/ZBTB7A/TGFBR2/MYH9/PTPN2/LTBR/ADAM17/EP300/IRF2BP2/SP3	71
GO:0070663	regulation of leukocyte proliferation	52/896	245/18722	5.16088471231103e-20	1.22008006312408e-17	MNDA/AIF1/LST1/TYROBP/IL1B/PTPRC/HLA-A/CD74/PYCARD/CORO1A/TNFSF13B/TNFRSF1B/HLA-DPA1/IRF1/HLA-DPB1/LYN/HLA-DRB1/TNFAIP3/HLA-E/BST2/LILRB2/HLA-DMB/RAC2/MEF2C/CEBPB/PTPN6/LILRB1/LGALS9/NCKAP1L/SYK/CD86/CCR2/BST1/CSF1R/MYD88/TNFRSF14/TLR4/CD300A/HHEX/SPN/INPP5D/BCL6/BTK/AHR/PKN1/CDKN1A/PRKAR1A/MAPK1/ATM/TGFBR2/IRS2/PRNP	52
GO:0045088	regulation of innate immune response	48/896	218/18722	2.88420417383736e-19	6.52206343831657e-17	FCN1/MNDA/TYROBP/NCF1/HLA-B/HLA-A/SAMHD1/PYCARD/IRF1/SPI1/CLEC7A/LYN/IFI16/FGR/ISG15/TNFAIP3/HLA-E/HCK/ARRB2/IRAK3/USP15/PTPN6/LILRB1/LGALS9/GRN/HLA-F/GBP5/SYK/PLSCR1/STAT2/TLR8/OAS1/LILRA2/TLR4/PARP9/BIRC3/FYN/IRF7/PARP14/IFI35/PAK1/PAK2/ADAR/PTPN2/NMI/CREBBP/EP300/BIRC2	48
GO:0022407	regulation of cell-cell adhesion	71/896	448/18722	3.16100931174206e-19	6.85017059598768e-17	AIF1/FGL2/IL1B/ITGB2/PTPRC/HLA-A/LAPTM5/HLA-DRA/CD74/PYCARD/CORO1A/LGALS1/CD44/TNFSF13B/HLA-DPA1/IRF1/B2M/SPI1/NFKBIZ/HLA-DPB1/LYN/FXYD5/KLF4/HLA-DRB1/HLA-E/LILRB2/HLA-DQB1/HLA-DMA/HLA-DMB/PLAUR/CD83/ITGA4/CEBPB/PTPN6/LILRB1/JAK2/LGALS9/IL1RN/MYADM/FERMT3/CD4/NCKAP1L/TGFB1/SYK/CD86/NLRP3/CCR2/CSK/TNF/TNFRSF14/ALOX5/RHOA/PTAFR/HLA-DQA1/MBP/FYN/CD300A/SPN/PAG1/SH2B3/BCL6/TNFAIP8L2/JAK1/PRKAR1A/DOCK8/SIRPA/MAP3K8/TGFBR2/PTPN2/PRNP/WNK1	71
GO:0002443	leukocyte mediated immunity	70/896	440/18722	4.6036588559579e-19	9.57745188393481e-17	TYROBP/IL1B/FCER1G/ITGB2/HLA-B/PTPRC/HLA-A/HLA-DRA/CD74/CORO1A/TNFRSF1B/HLA-DPA1/CCL3/STXBP2/B2M/SPI1/CLEC7A/HLA-DPB1/LYN/LYST/FGR/HLA-DRB1/HLA-E/BST2/ARRB2/SCIMP/WAS/HLA-DQB1/HLA-DMA/HLA-DMB/RAC2/PTPN6/LILRB1/CX3CR1/LGALS9/HLA-F/CTSH/NCKAP1L/TGFB1/SYK/MYO1G/NLRP3/CCR2/LAT2/PRAM1/TLR8/TREM1/TNF/MYD88/TCIRG1/STAT6/ITGAM/TLR4/GAPT/RAB27A/ADGRE2/PTAFR/HLA-DQA1/IRF7/CD300A/INPP5D/BCL6/BTK/AHR/CD84/KMT2E/HMOX1/ADAM17/DDX21/STX7	70
GO:1903037	regulation of leukocyte cell-cell adhesion	60/896	336/18722	5.67726278792777e-19	1.12180056637155e-16	AIF1/FGL2/IL1B/ITGB2/PTPRC/HLA-A/LAPTM5/HLA-DRA/CD74/PYCARD/CORO1A/LGALS1/CD44/TNFSF13B/HLA-DPA1/IRF1/B2M/NFKBIZ/HLA-DPB1/LYN/KLF4/HLA-DRB1/HLA-E/LILRB2/HLA-DQB1/HLA-DMA/HLA-DMB/CD83/ITGA4/CEBPB/PTPN6/LILRB1/LGALS9/CD4/NCKAP1L/SYK/CD86/NLRP3/CCR2/CSK/TNF/TNFRSF14/ALOX5/RHOA/PTAFR/HLA-DQA1/FYN/CD300A/SPN/PAG1/BCL6/TNFAIP8L2/PRKAR1A/DOCK8/SIRPA/MAP3K8/TGFBR2/PTPN2/PRNP/WNK1	60
GO:1903706	regulation of hemopoiesis	63/896	367/18722	5.82361378427837e-19	1.12180056637155e-16	FGL2/TYROBP/FOS/ZFP36/HLA-B/PTPRC/ZFP36L2/HLA-DRA/EVI2B/CD74/NFKBIA/CCL3/IRF1/B2M/SPI1/NFKBIZ/LYN/ISG15/HLA-DRB1/STAT1/LILRB3/LILRB2/MAFB/TMEM176B/MEF2C/CD83/CEBPB/PTPN6/LILRB1/CCR1/LGALS9/CD4/NCKAP1L/TGFB1/SYK/NOTCH2/CD86/NLRP3/CCR2/RASSF2/TNF/RHOA/TLR4/TMEM176A/NFAM1/IRF7/INPP5D/BCL6/BTK/JUN/PTK2B/ZFP36L1/HSPA1A/HCLS1/TRIB1/STAT3/RB1/KLF10/HIF1A/TGFBR2/PTPN2/CREB1/CIB1	63
GO:0046651	lymphocyte proliferation	55/896	288/18722	7.33505877032727e-19	1.36248716658829e-16	MNDA/AIF1/LST1/TYROBP/IL1B/PTPRC/HLA-A/CD74/PYCARD/CORO1A/TNFSF13B/TNFRSF1B/HLA-DPA1/IRF1/MSN/HLA-DPB1/SLC11A1/LYN/HLA-DRB1/HLA-E/LILRB2/HLA-DMB/RAC2/MEF2C/CEBPB/PTPN6/LILRB1/LGALS9/NCKAP1L/SYK/DOCK2/CD86/CCR2/BST1/MYD88/TNFRSF14/TLR4/GAPT/FYN/CD300A/SPN/INPP5D/BCL6/BTK/AHR/PKN1/CDKN1A/PSMB10/PRKAR1A/DOCK8/ATM/AZI2/TGFBR2/IRS2/PRNP	55
GO:0002697	regulation of immune effector process	60/896	339/18722	8.90071075193382e-19	1.59629643520027e-16	FGL2/TYROBP/IL1B/ITGB2/NCF1/HLA-B/PTPRC/HLA-A/LAPTM5/HLA-DRA/CD74/TNFRSF1B/STXBP2/B2M/SPI1/NFKBIZ/CLEC7A/LYN/CD36/FGR/HLA-DRB1/HLA-E/BST2/ARRB2/SCIMP/IRAK3/WAS/HLA-DMB/RAC2/PTPN6/LILRB1/CX3CR1/LGALS9/GRN/HLA-F/NCKAP1L/TGFB1/SYK/CD86/NLRP3/CCR2/PRAM1/TNF/TNFRSF14/STAT6/ITGAM/TLR4/ADGRE2/PTAFR/CD300A/BCL6/BTK/AHR/PKN1/CD84/RAP1A/HMOX1/TMBIM6/DDX21/STX7	60
GO:0032943	mononuclear cell proliferation	55/896	291/18722	1.20211293351374e-18	2.08406312240166e-16	MNDA/AIF1/LST1/TYROBP/IL1B/PTPRC/HLA-A/CD74/PYCARD/CORO1A/TNFSF13B/TNFRSF1B/HLA-DPA1/IRF1/MSN/HLA-DPB1/SLC11A1/LYN/HLA-DRB1/HLA-E/LILRB2/HLA-DMB/RAC2/MEF2C/CEBPB/PTPN6/LILRB1/LGALS9/NCKAP1L/SYK/DOCK2/CD86/CCR2/BST1/MYD88/TNFRSF14/TLR4/GAPT/FYN/CD300A/SPN/INPP5D/BCL6/BTK/AHR/PKN1/CDKN1A/PSMB10/PRKAR1A/DOCK8/ATM/AZI2/TGFBR2/IRS2/PRNP	55
GO:0050867	positive regulation of cell activation	67/896	420/18722	2.35802385864916e-18	3.95615551252718e-16	AIF1/TYROBP/IL1B/ITGB2/PTPRC/HLA-A/HLA-DRA/CD74/PYCARD/CORO1A/LGALS1/TNFSF13B/HLA-DPA1/CCL3/B2M/LRRK2/PLEK/NFKBIZ/CLEC7A/HLA-DPB1/LYN/FGR/HLA-DRB1/HLA-E/LILRB2/HLA-DQB1/HLA-DMA/HLA-DMB/MEF2C/CD83/PTPN6/LILRB1/JAK2/LGALS9/HLA-F/CD4/NCKAP1L/TGFB1/SYK/CD86/NLRP3/CCR2/BST1/CSK/LILRA5/LILRA2/MYD88/TNFRSF14/STAT6/ITGAM/RHOA/TLR4/PTAFR/HLA-DQA1/FYN/INPP5D/BCL6/BTK/SH3KBP1/JUND/CDKN1A/DOCK8/SIRPA/MAP3K8/TGFBR2/IRS2/BLOC1S6	67
GO:0050777	negative regulation of immune response	44/896	194/18722	2.73915354911999e-18	4.45198050280409e-16	FGL2/HLA-B/PTPRC/HLA-A/SAMHD1/SPI1/LYN/IFI16/FGR/ISG15/HLA-DRB1/TNFAIP3/HLA-E/HCK/ARRB2/IRAK3/USP15/PTPN6/LILRB1/GPX1/LGALS9/GRN/HLA-F/NCKAP1L/SYK/CCR2/STAT2/OAS1/TNFRSF14/STAT6/FYN/CD300A/INPP5D/BCL6/SAMSN1/AHR/PARP14/CD84/ADAR/PCBP2/SEC14L1/HMOX1/PTPN2/NMI	44
GO:0071706	tumor necrosis factor superfamily cytokine production	43/896	186/18722	3.09921240413744e-18	4.74088344527024e-16	TYROBP/CYBB/CYBA/CD14/TSPO/ZFP36/PTPRC/PYCARD/CCL3/LRRK2/CLEC7A/CD36/TNFAIP3/HLA-E/ARRB2/IRAK3/PTPN6/LILRB1/JAK2/CX3CR1/LGALS9/LY96/CLEC4A/TLR2/SYK/CD86/CCR2/LILRA5/OAS1/OAS2/LILRA2/MYD88/TLR4/CD33/PTAFR/SPN/TLR1/CD84/IFNGR1/STAT3/SIRPA/IFIH1/DICER1	43
GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	43/896	186/18722	3.09921240413744e-18	4.74088344527024e-16	TYROBP/CYBB/CYBA/CD14/TSPO/ZFP36/PTPRC/PYCARD/CCL3/LRRK2/CLEC7A/CD36/TNFAIP3/HLA-E/ARRB2/IRAK3/PTPN6/LILRB1/JAK2/CX3CR1/LGALS9/LY96/CLEC4A/TLR2/SYK/CD86/CCR2/LILRA5/OAS1/OAS2/LILRA2/MYD88/TLR4/CD33/PTAFR/SPN/TLR1/CD84/IFNGR1/STAT3/SIRPA/IFIH1/DICER1	43
GO:0006909	phagocytosis	56/896	308/18722	3.72292108302062e-18	5.53226072936864e-16	FCN1/AIF1/TYROBP/IL1B/CYBA/FCER1G/ITGB2/CD14/PTPRC/PYCARD/CORO1A/NCF2/CLEC7A/SLC11A1/LYN/LYST/CD36/FGR/CD302/HCK/FCGR1A/RAC2/PECAM1/CD93/TLR2/ITGAL/ICAM3/NCKAP1L/SYK/DOCK2/MYO1G/PLSCR1/CCR2/CSK/TNF/MYD88/ITGAM/TLR4/CD300LF/RAB27A/NCF4/FYN/CD300A/CNN2/IRF8/RHOG/RAP1A/PAK1/CDC42/ATG3/SIRPA/PTEN/BIN2/CORO1C/MYH9/CDC42SE1	56
GO:0002221	pattern recognition receptor signaling pathway	41/896	172/18722	5.83669969866067e-18	8.43240975909282e-16	FCN1/CTSS/CYBA/CD14/NFKBIA/IRF1/LYN/CD36/TNFAIP3/ARRB2/SCIMP/IRAK3/CLEC4E/USP15/LY96/TLR2/PIK3AP1/TLR8/OAS1/LILRA2/MYD88/TLR4/CD300LF/BIRC3/IRF7/CD300A/TLR1/BTK/MAPKAPK3/HSPA1A/UNC93B1/IFI35/RPS6KA3/CYLD/IFIH1/SEC14L1/PJA2/NMI/DDX3X/NINJ1/BIRC2	41
GO:0050670	regulation of lymphocyte proliferation	47/896	225/18722	6.49857296500982e-18	8.84769948658994e-16	MNDA/AIF1/LST1/TYROBP/IL1B/PTPRC/HLA-A/CD74/PYCARD/CORO1A/TNFSF13B/TNFRSF1B/HLA-DPA1/IRF1/HLA-DPB1/LYN/HLA-DRB1/HLA-E/LILRB2/HLA-DMB/RAC2/MEF2C/CEBPB/PTPN6/LILRB1/LGALS9/NCKAP1L/SYK/CD86/CCR2/BST1/MYD88/TNFRSF14/TLR4/CD300A/SPN/INPP5D/BCL6/BTK/AHR/PKN1/CDKN1A/PRKAR1A/ATM/TGFBR2/IRS2/PRNP	47
GO:0032640	tumor necrosis factor production	42/896	181/18722	6.63449874979826e-18	8.84769948658994e-16	TYROBP/CYBB/CYBA/CD14/TSPO/ZFP36/PTPRC/PYCARD/CCL3/LRRK2/CLEC7A/CD36/TNFAIP3/HLA-E/ARRB2/IRAK3/PTPN6/LILRB1/JAK2/CX3CR1/LGALS9/LY96/CLEC4A/TLR2/SYK/CCR2/LILRA5/OAS1/OAS2/LILRA2/MYD88/TLR4/CD33/PTAFR/SPN/TLR1/CD84/IFNGR1/STAT3/SIRPA/IFIH1/DICER1	42
GO:0032680	regulation of tumor necrosis factor production	42/896	181/18722	6.63449874979826e-18	8.84769948658994e-16	TYROBP/CYBB/CYBA/CD14/TSPO/ZFP36/PTPRC/PYCARD/CCL3/LRRK2/CLEC7A/CD36/TNFAIP3/HLA-E/ARRB2/IRAK3/PTPN6/LILRB1/JAK2/CX3CR1/LGALS9/LY96/CLEC4A/TLR2/SYK/CCR2/LILRA5/OAS1/OAS2/LILRA2/MYD88/TLR4/CD33/PTAFR/SPN/TLR1/CD84/IFNGR1/STAT3/SIRPA/IFIH1/DICER1	42
GO:0032635	interleukin-6 production	40/896	165/18722	7.84252207931282e-18	9.9485261791478e-16	AIF1/TYROBP/IL1B/CYBA/HLA-B/CD74/PYCARD/KLF2/POU2F2/CLEC7A/CD36/TNFAIP3/LILRB2/ARRB2/SCIMP/IRAK3/CEBPB/PTPN6/IL17RA/LGALS9/TLR2/NCKAP1L/SYK/TLR8/CSK/LILRA5/LILRA2/TNF/MYD88/IL6R/TLR4/PTAFR/MBP/INPP5D/TLR1/CAPN2/CD84/STAT3/SIRPA/IFIH1	40
GO:0032675	regulation of interleukin-6 production	40/896	165/18722	7.84252207931282e-18	9.9485261791478e-16	AIF1/TYROBP/IL1B/CYBA/HLA-B/CD74/PYCARD/KLF2/POU2F2/CLEC7A/CD36/TNFAIP3/LILRB2/ARRB2/SCIMP/IRAK3/CEBPB/PTPN6/IL17RA/LGALS9/TLR2/NCKAP1L/SYK/TLR8/CSK/LILRA5/LILRA2/TNF/MYD88/IL6R/TLR4/PTAFR/MBP/INPP5D/TLR1/CAPN2/CD84/STAT3/SIRPA/IFIH1	40
GO:0045936	negative regulation of phosphate metabolic process	68/896	441/18722	8.19752526900664e-18	1.01512687914532e-15	IL1B/DUSP1/PTPRC/RGS2/PYCARD/DUSP6/LRRK2/GADD45B/PLEK/LYN/GNAI2/TNFAIP3/ARRB2/IRAK3/SOCS3/PTPN6/MYADM/NCKAP1L/TGFB1/CDA/SORL1/SLC8A1/CSK/RASSF2/TNF/CD300A/HHEX/SH2B3/FBP1/SAMSN1/MIDN/FKBP1A/PARP14/PPP1R15A/CALM2/TRIB1/PKN1/CHP1/C9orf72/PRKAG2/PAK2/CDKN1A/PRKAR1A/STAT3/GNAQ/SIRPA/ROCK1/YWHAB/STK38/PTEN/HIPK3/RB1/BOD1L1/ADAR/PPP1R15B/PIP4K2A/CORO1C/HNRNPU/IRS2/DUSP22/PTPN2/MVP/PRNP/PLEC/NUP62/CTDSP1/WNK1/CIB1	68
GO:0010563	negative regulation of phosphorus metabolic process	68/896	442/18722	9.25779673767409e-18	1.11610772751225e-15	IL1B/DUSP1/PTPRC/RGS2/PYCARD/DUSP6/LRRK2/GADD45B/PLEK/LYN/GNAI2/TNFAIP3/ARRB2/IRAK3/SOCS3/PTPN6/MYADM/NCKAP1L/TGFB1/CDA/SORL1/SLC8A1/CSK/RASSF2/TNF/CD300A/HHEX/SH2B3/FBP1/SAMSN1/MIDN/FKBP1A/PARP14/PPP1R15A/CALM2/TRIB1/PKN1/CHP1/C9orf72/PRKAG2/PAK2/CDKN1A/PRKAR1A/STAT3/GNAQ/SIRPA/ROCK1/YWHAB/STK38/PTEN/HIPK3/RB1/BOD1L1/ADAR/PPP1R15B/PIP4K2A/CORO1C/HNRNPU/IRS2/DUSP22/PTPN2/MVP/PRNP/PLEC/NUP62/CTDSP1/WNK1/CIB1	68
GO:0032944	regulation of mononuclear cell proliferation	47/896	227/18722	9.44217266113039e-18	1.11610772751225e-15	MNDA/AIF1/LST1/TYROBP/IL1B/PTPRC/HLA-A/CD74/PYCARD/CORO1A/TNFSF13B/TNFRSF1B/HLA-DPA1/IRF1/HLA-DPB1/LYN/HLA-DRB1/HLA-E/LILRB2/HLA-DMB/RAC2/MEF2C/CEBPB/PTPN6/LILRB1/LGALS9/NCKAP1L/SYK/CD86/CCR2/BST1/MYD88/TNFRSF14/TLR4/CD300A/SPN/INPP5D/BCL6/BTK/AHR/PKN1/CDKN1A/PRKAR1A/ATM/TGFBR2/IRS2/PRNP	47
GO:0071222	cellular response to lipopolysaccharide	45/896	209/18722	9.67359905553261e-18	1.11805308195167e-15	IL1B/CD14/TSPO/ZFP36/VIM/PYCARD/NFKBIA/CARD16/TNFRSF1B/CCL3/SPI1/LYN/CD36/CASP1/TNFAIP3/LILRB2/HCK/CD68/SCIMP/MTDH/CXCL8/MEF2C/CEBPB/LILRB1/CX3CR1/LY86/LY96/TLR2/TGFB1/CD86/NLRP3/LILRA2/TNF/MYD88/RHOA/TLR4/PTAFR/IRF8/CAPN2/TRIB1/LITAF/SIRPA/CARD8/MAPK1/NFKB1	45
GO:0071219	cellular response to molecule of bacterial origin	46/896	221/18722	1.70287344426717e-17	1.91168226069763e-15	IL1B/CD14/TSPO/ZFP36/VIM/PYCARD/NFKBIA/CARD16/TNFRSF1B/CCL3/SPI1/LYN/CD36/CASP1/TNFAIP3/LILRB2/HCK/CD68/SCIMP/MTDH/CXCL8/MEF2C/CEBPB/LILRB1/CX3CR1/LY86/LY96/TLR2/TGFB1/CD86/NLRP3/LILRA2/TNF/MYD88/RHOA/TLR4/PTAFR/TLR1/IRF8/CAPN2/TRIB1/LITAF/SIRPA/CARD8/MAPK1/NFKB1	46
GO:0002224	toll-like receptor signaling pathway	34/896	121/18722	1.72753444054583e-17	1.91168226069763e-15	CTSS/CYBA/CD14/NFKBIA/IRF1/LYN/CD36/TNFAIP3/ARRB2/SCIMP/IRAK3/LY96/TLR2/PIK3AP1/TLR8/OAS1/LILRA2/MYD88/TLR4/CD300LF/BIRC3/IRF7/CD300A/TLR1/BTK/MAPKAPK3/UNC93B1/IFI35/RPS6KA3/PJA2/NMI/DDX3X/NINJ1/BIRC2	34
GO:0050727	regulation of inflammatory response	62/896	386/18722	3.25439350727871e-17	3.52627096486596e-15	S100A9/S100A8/IL1B/NCF1/ZFP36/TMSB4X/PTPRC/S100A12/PYCARD/NFKBIA/NEAT1/TNFRSF1B/CCL3/LRRK2/NFKBIZ/LYN/KLF4/FGR/HLA-DRB1/CASP1/PTGS2/TNFAIP3/HLA-E/HCK/GPSM3/SOCS3/AOAH/CEBPB/IL17RA/GPX1/JAK2/ZYX/GRN/TLR2/SYK/NLRP3/PIK3AP1/CCR2/BST1/LILRA5/TNF/MYD88/ALOX5/TLR4/BIRC3/FYN/BCL6/TNFAIP8L2/BTK/METRNL/IFI35/ALOX5AP/TNFRSF1A/SIRPA/CYLD/RB1/PTPN2/CELF1/NMI/NINJ1/NFKB1/BIRC2	62
GO:0002703	regulation of leukocyte mediated immunity	46/896	226/18722	4.27481800166931e-17	4.53741396462899e-15	TYROBP/IL1B/ITGB2/HLA-B/PTPRC/HLA-A/HLA-DRA/TNFRSF1B/STXBP2/B2M/SPI1/CLEC7A/LYN/FGR/HLA-DRB1/HLA-E/BST2/ARRB2/SCIMP/WAS/RAC2/PTPN6/LILRB1/CX3CR1/LGALS9/HLA-F/NCKAP1L/TGFB1/SYK/NLRP3/CCR2/PRAM1/TNF/STAT6/ITGAM/TLR4/ADGRE2/PTAFR/CD300A/BCL6/BTK/AHR/CD84/HMOX1/DDX21/STX7	46
GO:0071346	cellular response to interferon-gamma	33/896	118/18722	6.03404857569301e-17	6.27661732843586e-15	AIF1/VIM/CCL3L3/HLA-DPA1/CCL3/IRF1/CASP1/GBP1/STAT1/HCK/ACTR2/WAS/GBP2/IFNGR2/JAK2/LGALS9/ZYX/TLR2/GBP4/GBP5/TLR4/PARP9/CCL4/IRF8/JAK1/PARP14/ACTR3/SP100/IFNGR1/CDC42/SIRPA/PTPN2/NMI	33
GO:1903039	positive regulation of leukocyte cell-cell adhesion	47/896	239/18722	8.09327477498541e-17	8.23154207062561e-15	AIF1/IL1B/ITGB2/PTPRC/HLA-A/HLA-DRA/CD74/PYCARD/CORO1A/LGALS1/CD44/TNFSF13B/HLA-DPA1/B2M/NFKBIZ/HLA-DPB1/LYN/HLA-DRB1/HLA-E/LILRB2/HLA-DQB1/HLA-DMA/HLA-DMB/CD83/ITGA4/PTPN6/LILRB1/LGALS9/CD4/NCKAP1L/SYK/CD86/NLRP3/CCR2/CSK/TNF/TNFRSF14/ALOX5/RHOA/PTAFR/HLA-DQA1/FYN/BCL6/DOCK8/SIRPA/MAP3K8/TGFBR2	47
GO:0031349	positive regulation of defense response	51/896	278/18722	8.22995938612827e-17	8.23154207062561e-15	FCN1/S100A9/MNDA/S100A8/TYROBP/IL1B/CYBA/S100A12/PYCARD/NFKBIA/NEAT1/CCL3/SPI1/LRRK2/NFKBIZ/CLEC7A/LYN/IFI16/PTGS2/HLA-E/HCK/GPSM3/MEF2C/CEBPB/IL17RA/JAK2/GRN/HLA-F/TLR2/GBP5/SYK/PLSCR1/CCR2/TLR8/LILRA5/LILRA2/TNF/TLR4/PARP9/FYN/IRF7/BTK/IFI35/ALOX5AP/PAK1/PAK2/TNFRSF1A/NMI/CREBBP/EP300/NINJ1	51
GO:0002275	myeloid cell activation involved in immune response	29/896	91/18722	9.56719015070265e-17	9.26615702376674e-15	TYROBP/FCER1G/ITGB2/PYCARD/CCL3/STXBP2/SPI1/LYN/FGR/RAC2/CX3CR1/LGALS9/GRN/SYK/DOCK2/CCR2/LAT2/PRAM1/LILRA2/MYD88/ITGAM/ADGRE2/PTAFR/CD300A/BTK/IFI35/CD84/HMOX1/NMI	29
GO:1902105	regulation of leukocyte differentiation	51/896	279/18722	9.62069754438385e-17	9.26615702376674e-15	FGL2/TYROBP/FOS/HLA-B/PTPRC/ZFP36L2/HLA-DRA/EVI2B/CD74/CCL3/IRF1/NFKBIZ/LYN/HLA-DRB1/LILRB3/LILRB2/MAFB/TMEM176B/CD83/CEBPB/PTPN6/LILRB1/CCR1/LGALS9/CD4/NCKAP1L/TGFB1/SYK/NOTCH2/CD86/NLRP3/CCR2/RASSF2/TNF/RHOA/TLR4/TMEM176A/NFAM1/IRF7/INPP5D/BCL6/BTK/JUN/ZFP36L1/HCLS1/TRIB1/RB1/KLF10/TGFBR2/PTPN2/CREB1	51
GO:0031663	lipopolysaccharide-mediated signaling pathway	24/896	60/18722	1.0753174538045e-16	1.0168592867704e-14	IL1B/CD14/NFKBIA/CARD16/CCL3/SPI1/LYN/CD36/TNFAIP3/HCK/SCIMP/MTDH/LY86/LY96/TLR2/TGFB1/LILRA2/TNF/MYD88/TLR4/PTAFR/TRIB1/CARD8/MAPK1	24
GO:0007015	actin filament organization	66/896	441/18722	1.19414612875486e-16	1.10906321708108e-14	AIF1/LCP1/TMSB4X/COTL1/PYCARD/CORO1A/GMFG/PLEK/FLNA/MYO1F/RHOB/HCK/ACTR2/MARCKS/WAS/TMSB10/RAC2/TPM3/JAK2/ZYX/VASP/WIPF1/MYADM/NCKAP1L/MYO1G/ARPC1B/ARPC3/CCDC88A/CAPG/RHOA/PHACTR1/GAS7/PSTPIP1/GPR65/PREX1/PTK2B/MSRB1/RHOG/HCLS1/ACTR3/SH3KBP1/ARAP1/CDC42EP3/ARPC4/CFL1/CAPZA1/C9orf72/SHTN1/PAK1/MTPN/CAPZA2/PAK2/GRB2/TWF2/CDC42/DIAPH1/ROCK1/PFN1/DBNL/ARPC5/FLII/SSH2/BRK1/CORO1C/ABI1/PLEC	66
GO:0007249	I-kappaB kinase/NF-kappaB signaling	51/896	281/18722	1.31155064354784e-16	1.19673243808637e-14	S100A4/IL1B/S100A12/CD74/PYCARD/LGALS1/NFKBIA/CARD16/TNFSF10/CLEC7A/FLNA/CD36/HLA-DRB1/CASP1/TNFAIP3/STAT1/BST2/MTDH/SECTM1/CX3CR1/LGALS9/PRKCB/TLR2/TRIM22/CD4/TLR8/TNF/MYD88/RHOA/TLR4/BIRC3/FYN/BTK/MAP3K3/AKAP13/FKBP1A/TRIM38/REL/LITAF/TNFRSF1A/SIRPA/CFLAR/ROCK1/CARD8/TANK/AZI2/HMOX1/LTBR/DDX21/NUP62/BIRC2	51
GO:0002696	positive regulation of leukocyte activation	63/896	409/18722	1.46575568949055e-16	1.31437850707592e-14	AIF1/TYROBP/IL1B/ITGB2/PTPRC/HLA-A/HLA-DRA/CD74/PYCARD/CORO1A/LGALS1/TNFSF13B/HLA-DPA1/CCL3/B2M/LRRK2/NFKBIZ/CLEC7A/HLA-DPB1/LYN/FGR/HLA-DRB1/HLA-E/LILRB2/HLA-DQB1/HLA-DMA/HLA-DMB/MEF2C/CD83/PTPN6/LILRB1/LGALS9/HLA-F/CD4/NCKAP1L/TGFB1/SYK/CD86/NLRP3/CCR2/BST1/CSK/MYD88/TNFRSF14/STAT6/ITGAM/RHOA/TLR4/PTAFR/HLA-DQA1/FYN/INPP5D/BCL6/BTK/SH3KBP1/JUND/CDKN1A/DOCK8/SIRPA/MAP3K8/TGFBR2/IRS2/BLOC1S6	63
GO:0042113	B cell activation	56/896	334/18722	1.65177933125865e-16	1.45608547489427e-14	MNDA/TYROBP/PTPRC/LAPTM5/ZFP36L2/CD74/LGALS1/TNFSF13B/KLF6/SPI1/LYN/TNFAIP3/BST2/MEF2C/THEMIS2/SKAP2/ITGA4/PTPN6/PRKCB/NCKAP1L/TGFB1/SYK/NOTCH2/CD86/LAT2/BST1/LFNG/TCIRG1/STAT6/TLR4/GAPT/NFAM1/DOCK11/CD300A/HHEX/LYL1/INPP5D/BCL6/BTK/IRF8/PTK2B/ZFP36L1/SAMSN1/AHR/SH3KBP1/CMTM7/PKN1/CDKN1A/ATM/ZBTB7A/IRS2/PTPN2/ADAM17/EP300/IRF2BP2/SP3	56
GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	31/896	107/18722	1.76017380063944e-16	1.52577732285429e-14	TYROBP/CYBB/CYBA/CD14/PTPRC/PYCARD/CCL3/LRRK2/CLEC7A/CD36/HLA-E/JAK2/LGALS9/LY96/TLR2/SYK/CD86/CCR2/LILRA5/OAS1/OAS2/LILRA2/MYD88/TLR4/PTAFR/SPN/TLR1/CD84/IFNGR1/STAT3/IFIH1	31
GO:0048002	antigen processing and presentation of peptide antigen	24/896	62/18722	2.63955727502554e-16	2.25054711268981e-14	CTSS/FCER1G/HLA-B/HLA-C/HLA-A/HLA-DRA/CD74/PYCARD/HLA-DPA1/B2M/HLA-DPB1/SLC11A1/IFI30/HLA-DRB1/HLA-E/HLA-DQB1/HLA-DMA/HLA-DMB/HLA-F/CLEC4A/HLA-DQA1/TAP1/TAPBP/LNPEP	24
GO:0045785	positive regulation of cell adhesion	65/896	437/18722	2.80315375582023e-16	2.35148430387435e-14	AIF1/IL1B/ITGB2/PTPRC/HLA-A/HLA-DRA/CD74/PYCARD/CORO1A/LGALS1/CD44/TNFSF13B/HLA-DPA1/B2M/NFKBIZ/HLA-DPB1/LYN/FLNA/CD36/HLA-DRB1/HLA-E/LILRB2/HLA-DQB1/HLA-DMA/HLA-DMB/PLAUR/CD83/ITGA4/PTPN6/LILRB1/JAK2/LGALS9/IQGAP1/MYADM/CD4/NCKAP1L/SYK/CD86/NLRP3/CCR2/CSK/APBB1IP/TNF/TNFRSF14/ALOX5/RHOA/PTAFR/HLA-DQA1/FYN/BCL6/PREX1/PTK2B/JAK1/STK4/CDC42/DOCK8/RRAS/SIRPA/ROCK1/LIMS1/ATM/MAP3K8/TGFBR2/PPP3CA/CIB1	65
GO:0032760	positive regulation of tumor necrosis factor production	30/896	103/18722	4.6036860722027e-16	3.80059861294068e-14	TYROBP/CYBB/CYBA/CD14/PTPRC/PYCARD/CCL3/LRRK2/CLEC7A/CD36/HLA-E/JAK2/LGALS9/LY96/TLR2/SYK/CCR2/LILRA5/OAS1/OAS2/LILRA2/MYD88/TLR4/PTAFR/SPN/TLR1/CD84/IFNGR1/STAT3/IFIH1	30
GO:0002695	negative regulation of leukocyte activation	40/896	187/18722	8.24067344541079e-16	6.69683477962211e-14	MNDA/FGL2/LST1/TYROBP/PTPRC/LAPTM5/CD74/IRF1/SPI1/LYN/FGR/HLA-DRB1/TNFAIP3/LILRB2/CEBPB/PTPN6/LILRB1/LGALS9/GRN/HLA-F/NCKAP1L/CD86/CCR2/TNFRSF14/CD300LF/CD300A/SPN/PAG1/INPP5D/BCL6/TNFAIP8L2/BTK/SAMSN1/PKN1/CD84/PRKAR1A/ATM/HMOX1/PTPN2/PRNP	40
GO:0022409	positive regulation of cell-cell adhesion	50/896	284/18722	9.47056576872615e-16	7.57790962509918e-14	AIF1/IL1B/ITGB2/PTPRC/HLA-A/HLA-DRA/CD74/PYCARD/CORO1A/LGALS1/CD44/TNFSF13B/HLA-DPA1/B2M/NFKBIZ/HLA-DPB1/LYN/HLA-DRB1/HLA-E/LILRB2/HLA-DQB1/HLA-DMA/HLA-DMB/PLAUR/CD83/ITGA4/PTPN6/LILRB1/JAK2/LGALS9/CD4/NCKAP1L/SYK/CD86/NLRP3/CCR2/CSK/TNF/TNFRSF14/ALOX5/RHOA/PTAFR/HLA-DQA1/FYN/BCL6/JAK1/DOCK8/SIRPA/MAP3K8/TGFBR2	50
GO:0002478	antigen processing and presentation of exogenous peptide antigen	19/896	38/18722	1.02853675210041e-15	8.10518128435488e-14	CTSS/FCER1G/HLA-A/HLA-DRA/CD74/HLA-DPA1/B2M/HLA-DPB1/IFI30/HLA-DRB1/HLA-E/HLA-DQB1/HLA-DMA/HLA-DMB/HLA-F/CLEC4A/HLA-DQA1/TAP1/LNPEP	19
GO:0008154	actin polymerization or depolymerization	43/896	217/18722	1.27347573014879e-15	9.88559294403563e-14	AIF1/TMSB4X/COTL1/PYCARD/CORO1A/GMFG/PLEK/HCK/ACTR2/WAS/TMSB10/JAK2/VASP/WIPF1/MYADM/NCKAP1L/ARPC1B/ARPC3/CAPG/RHOA/GAS7/PSTPIP1/PREX1/PTK2B/MSRB1/HCLS1/ACTR3/CDC42EP3/ARPC4/CFL1/CAPZA1/MTPN/CAPZA2/GRB2/TWF2/DIAPH1/PFN1/DBNL/ARPC5/FLII/SSH2/BRK1/ABI1	43
GO:0002573	myeloid leukocyte differentiation	42/896	208/18722	1.36280248070666e-15	1.04234348561108e-13	TYROBP/FOS/JUNB/EVI2B/CD74/CCL3/SPI1/LYN/IFI16/HLA-DRB1/SNX10/LILRB3/MAFB/CEBPB/LILRB1/CCR1/TLR2/CD4/TGFB1/NOTCH2/OSCAR/CSF1R/RASSF2/TNF/TCIRG1/TLR4/IRF7/INPP5D/JUN/ZFP36L1/HCLS1/TRIB1/CDC42/RB1/KLF10/TGFBR2/LBR/MYH9/PTPN2/LTBR/SP3/CREB1	42
GO:0050863	regulation of T cell activation	54/896	329/18722	1.48562590259209e-15	1.11981743759151e-13	AIF1/FGL2/IL1B/PTPRC/HLA-A/LAPTM5/HLA-DRA/CD74/PYCARD/CORO1A/LGALS1/TNFSF13B/TNFRSF1B/HLA-DPA1/IRF1/B2M/NFKBIZ/HLA-DPB1/LYN/HLA-DRB1/HLA-E/LILRB2/HLA-DQB1/HLA-DMA/HLA-DMB/RAC2/CD83/CEBPB/PTPN6/LILRB1/LGALS9/CD4/NCKAP1L/SYK/CD86/NLRP3/CCR2/CSK/TNFRSF14/RHOA/HLA-DQA1/FYN/CD300A/SPN/PAG1/BCL6/TNFAIP8L2/PRKAR1A/DOCK8/SIRPA/MAP3K8/TGFBR2/PTPN2/PRNP	54
GO:0042326	negative regulation of phosphorylation	59/896	385/18722	1.76982177211702e-15	1.31497757668295e-13	IL1B/DUSP1/PTPRC/RGS2/PYCARD/DUSP6/LRRK2/GADD45B/LYN/TNFAIP3/ARRB2/IRAK3/SOCS3/PTPN6/MYADM/TGFB1/SORL1/SLC8A1/CSK/RASSF2/CD300A/HHEX/SH2B3/FBP1/SAMSN1/MIDN/PARP14/CALM2/TRIB1/PKN1/CHP1/C9orf72/PRKAG2/PAK2/CDKN1A/PRKAR1A/STAT3/GNAQ/SIRPA/ROCK1/STK38/PTEN/HIPK3/RB1/ADAR/PPP1R15B/PIP4K2A/CORO1C/HNRNPU/IRS2/DUSP22/PTPN2/MVP/PRNP/PLEC/NUP62/CTDSP1/WNK1/CIB1	59
GO:0030098	lymphocyte differentiation	58/896	374/18722	1.79512875907e-15	1.3149950247779e-13	FGL2/IL1B/FCER1G/PTPRC/ZFP36L2/HLA-DRA/CD74/LGALS1/TNFSF13B/KLF6/IRF1/B2M/SPI1/NFKBIZ/EGR1/HLA-DRB1/LILRB2/MAFB/CD83/ITGA4/PTPN6/LGALS9/CD4/NCKAP1L/SYK/DOCK2/NOTCH2/CD86/NLRP3/CCR2/LFNG/TCIRG1/STAT6/RHOA/IL6R/IKZF1/NFAM1/DOCK11/HHEX/SPN/LYL1/INPP5D/BCL6/BTK/IRF8/PREX1/PTK2B/ZFP36L1/CMTM7/STAT3/ATM/ZBTB7A/TGFBR2/PTPN2/ADAM17/EP300/IRF2BP2/SP3	58
GO:0032956	regulation of actin cytoskeleton organization	56/896	357/18722	3.35791170984813e-15	2.42562483373891e-13	TMSB4X/COTL1/PYCARD/CORO1A/GMFG/ARHGDIB/PLEK/FLNA/RHOB/BST2/HCK/ACTR2/WAS/TMSB10/RAC2/IQGAP1/VASP/MYADM/NCKAP1L/NOTCH2/ARPC1B/ARPC3/BST1/CCDC88A/CSF1R/CAPG/RHOA/GPR65/PREX1/PTK2B/RHOG/AKAP13/HCLS1/ACTR3/ARAP1/CDC42EP3/ARPC4/CAPZA1/C9orf72/RHOQ/PAK1/MTPN/CAPZA2/PAK2/GRB2/TWF2/CDC42/ROCK1/PFN1/DBNL/ARPC5/FLII/SSH2/BRK1/TAOK1/ARHGDIA	56
GO:0002699	positive regulation of immune effector process	44/896	235/18722	5.18370134646254e-15	3.63302050820279e-13	TYROBP/IL1B/ITGB2/HLA-B/PTPRC/HLA-A/LAPTM5/HLA-DRA/CD74/STXBP2/B2M/SPI1/NFKBIZ/CLEC7A/LYN/CD36/FGR/HLA-DRB1/HLA-E/SCIMP/HLA-DMB/RAC2/LILRB1/LGALS9/HLA-F/TGFB1/SYK/CD86/NLRP3/CCR2/TNF/TNFRSF14/STAT6/ITGAM/TLR4/ADGRE2/PTAFR/CD300A/BTK/CD84/RAP1A/HMOX1/DDX21/STX7	44
GO:0051607	defense response to virus	47/896	265/18722	5.23892593953489e-15	3.63302050820279e-13	FGL2/APOBEC3A/PTPRC/SAMHD1/PYCARD/IFITM3/IRF1/IFIT2/LYST/IFI16/ISG15/TNFAIP3/GBP1/STAT1/BST2/IFIT3/USP15/IFNGR2/IFI44L/MX1/LILRB1/IFITM2/TLR2/TRIM22/MX2/RNASE6/PLSCR1/STAT2/TLR8/OAS1/OAS2/MYD88/ITGAX/PARP9/BIRC3/IRF7/UNC93B1/DTX3L/BNIP3L/CARD8/IFIH1/IRF2/ADAR/PCBP2/SEC14L1/DDX21/BIRC2	47
GO:0140546	defense response to symbiont	47/896	265/18722	5.23892593953489e-15	3.63302050820279e-13	FGL2/APOBEC3A/PTPRC/SAMHD1/PYCARD/IFITM3/IRF1/IFIT2/LYST/IFI16/ISG15/TNFAIP3/GBP1/STAT1/BST2/IFIT3/USP15/IFNGR2/IFI44L/MX1/LILRB1/IFITM2/TLR2/TRIM22/MX2/RNASE6/PLSCR1/STAT2/TLR8/OAS1/OAS2/MYD88/ITGAX/PARP9/BIRC3/IRF7/UNC93B1/DTX3L/BNIP3L/CARD8/IFIH1/IRF2/ADAR/PCBP2/SEC14L1/DDX21/BIRC2	47
GO:0051251	positive regulation of lymphocyte activation	56/896	362/18722	6.22292221951467e-15	4.25860769259156e-13	AIF1/TYROBP/IL1B/PTPRC/HLA-A/HLA-DRA/CD74/PYCARD/CORO1A/LGALS1/TNFSF13B/HLA-DPA1/B2M/NFKBIZ/CLEC7A/HLA-DPB1/LYN/HLA-DRB1/HLA-E/LILRB2/HLA-DQB1/HLA-DMA/HLA-DMB/MEF2C/CD83/PTPN6/LILRB1/LGALS9/HLA-F/CD4/NCKAP1L/TGFB1/SYK/CD86/NLRP3/CCR2/BST1/CSK/MYD88/TNFRSF14/STAT6/RHOA/TLR4/HLA-DQA1/FYN/INPP5D/BCL6/BTK/SH3KBP1/CDKN1A/DOCK8/SIRPA/MAP3K8/TGFBR2/IRS2/BLOC1S6	56
GO:0032970	regulation of actin filament-based process	59/896	396/18722	6.47650434045918e-15	4.37458429541924e-13	TMSB4X/COTL1/PYCARD/CORO1A/GMFG/ARHGDIB/PLEK/FLNA/RHOB/BST2/HCK/ACTR2/WAS/TMSB10/RAC2/IQGAP1/VASP/MYADM/NCKAP1L/NOTCH2/ARPC1B/ARPC3/BST1/CCDC88A/CSF1R/CAPG/RHOA/GPR65/CNN2/PREX1/PTK2B/RHOG/AKAP13/HCLS1/ACTR3/ARAP1/CDC42EP3/ARPC4/CAPZA1/C9orf72/RHOQ/PAK1/MTPN/CAPZA2/PAK2/GRB2/TWF2/CDC42/ROCK1/PFN1/ABRACL/DBNL/ARPC5/FLII/SSH2/BRK1/MYH9/TAOK1/ARHGDIA	59
GO:0030041	actin filament polymerization	39/896	190/18722	8.06443886751575e-15	5.37732648076274e-13	AIF1/TMSB4X/COTL1/PYCARD/CORO1A/GMFG/HCK/ACTR2/WAS/TMSB10/JAK2/VASP/MYADM/NCKAP1L/ARPC1B/ARPC3/CAPG/RHOA/GAS7/PSTPIP1/PREX1/PTK2B/MSRB1/HCLS1/ACTR3/CDC42EP3/ARPC4/CAPZA1/MTPN/CAPZA2/GRB2/TWF2/DIAPH1/PFN1/DBNL/ARPC5/FLII/SSH2/BRK1	39
GO:0019884	antigen processing and presentation of exogenous antigen	20/896	47/18722	9.23890327270324e-15	6.08247290143412e-13	CTSS/FCER1G/HLA-A/HLA-DRA/CD74/HLA-DPA1/B2M/HLA-DPB1/IFI30/HLA-DRB1/HLA-E/HLA-DQB1/HLA-DMA/HLA-DMB/HLA-F/CLEC4A/HLA-DQA1/TAP1/PSME1/LNPEP	20
GO:0045637	regulation of myeloid cell differentiation	41/896	210/18722	1.00551031731422e-14	6.45636933376696e-13	TYROBP/FOS/ZFP36/EVI2B/CD74/NFKBIA/CCL3/B2M/SPI1/LYN/ISG15/HLA-DRB1/STAT1/LILRB3/MAFB/MEF2C/CEBPB/LILRB1/CCR1/CD4/NCKAP1L/TGFB1/NOTCH2/RASSF2/TNF/TLR4/IRF7/INPP5D/JUN/PTK2B/ZFP36L1/HSPA1A/HCLS1/TRIB1/STAT3/RB1/KLF10/HIF1A/PTPN2/CREB1/CIB1	41
GO:0050866	negative regulation of cell activation	41/896	210/18722	1.00551031731422e-14	6.45636933376696e-13	MNDA/FGL2/LST1/TYROBP/PTPRC/LAPTM5/CD74/IRF1/SPI1/LYN/FGR/HLA-DRB1/TNFAIP3/LILRB2/CEBPB/PTPN6/LILRB1/LGALS9/GRN/HLA-F/NCKAP1L/CD86/CCR2/TNFRSF14/CD300LF/CD300A/SPN/PAG1/INPP5D/SH2B3/BCL6/TNFAIP8L2/BTK/SAMSN1/PKN1/CD84/PRKAR1A/ATM/HMOX1/PTPN2/PRNP	41
GO:0030595	leukocyte chemotaxis	43/896	230/18722	1.12196531292348e-14	7.1162702347744e-13	S100A9/S100A8/AIF1/FCER1G/ITGB2/DUSP1/S100A12/CCL3L3/CD74/CORO1A/CCL3/JAML/SPI1/C5AR1/LYN/LYST/GPSM3/CXCL8/RAC2/CX3CR1/CCR1/LGALS9/NCKAP1L/SYK/CCR2/BST1/CSF1R/CXCR4/TREM1/ALOX5/IL6R/RIN3/ADGRE2/CCL4/PREX1/PTK2B/CKLF/ADAM10/MAPK1/ADAM17/PLEC/NINJ1/WNK1	43
GO:0002819	regulation of adaptive immune response	38/896	183/18722	1.20691589240535e-14	7.56285488722921e-13	IL1B/HLA-B/PTPRC/HLA-A/HLA-DRA/PYCARD/TNFSF13B/TNFRSF1B/CD48/IRF1/B2M/NFKBIZ/CLEC7A/SLC11A1/HLA-DRB1/TNFAIP3/HLA-E/WAS/MEF2C/PTPN6/LILRB1/HLA-F/CD4/NCKAP1L/TGFB1/NLRP3/CCR2/TNF/TNFRSF14/STAT6/IRF7/BCL6/BTK/SAMSN1/AHR/PKN1/ADCY7/STX7	38
GO:0032755	positive regulation of interleukin-6 production	27/896	93/18722	1.48458974075457e-14	9.19208481150535e-13	AIF1/TYROBP/IL1B/CYBA/CD74/PYCARD/POU2F2/CLEC7A/CD36/LILRB2/SCIMP/IL17RA/LGALS9/TLR2/SYK/TLR8/LILRA5/LILRA2/TNF/MYD88/IL6R/TLR4/PTAFR/MBP/TLR1/STAT3/IFIH1	27
GO:0043254	regulation of protein-containing complex assembly	61/896	427/18722	1.58218167618999e-14	9.68109046807544e-13	LCP1/TMSB4X/COTL1/PYCARD/CORO1A/GMFG/MSN/PLEK/CLEC7A/CD36/ISG15/HCK/ACTR2/WAS/TMSB10/VASP/MYADM/GBP5/NCKAP1L/TGFB1/SYK/ARPC1B/ARPC3/SORL1/BID/CAPG/TNF/MYD88/RHOA/TLR4/PREX1/PTK2B/EIF4EBP1/HSPA1A/HCLS1/ACTR3/RALB/CDC42EP3/ARPC4/NIN/CAPZA1/PAK1/MTPN/CAPZA2/GRB2/TWF2/CDC42/RB1/PFN1/CARD8/RAP1B/DBNL/ARPC5/ATM/FLII/SSH2/BRK1/DDX3X/EP300/CREB1/BIRC2	61
GO:0002768	immune response-regulating cell surface receptor signaling pathway	51/896	315/18722	1.63071713462559e-14	9.86204629905544e-13	FCN1/MNDA/TYROBP/FCER1G/PTPRC/HLA-A/LAPTM5/FPR1/C5AR1/NFKBIZ/CLEC7A/HLA-DPB1/LYN/FGR/HLA-DRB1/GBP1/LILRB2/HCK/HLA-DQB1/MEF2C/THEMIS2/PTPN6/LILRB1/PRKCB/MAP3K1/NCKAP1L/SYK/MYO1G/PLSCR1/LAT2/PRAM1/CSK/LCP2/LILRA2/FCGR1B/NFAM1/FYN/CD300A/INPP5D/BTK/CMTM3/RAP1A/PAK1/PAK2/MAPK1/DGKZ/PTPN2/PRNP/CREBBP/EP300/WNK1	51
GO:0034612	response to tumor necrosis factor	45/896	253/18722	1.80348888574654e-14	1.07815467755951e-12	CYBA/CD14/ZFP36/TMSB4X/CCL3L3/LAPTM5/ZFP36L2/PYCARD/NFKBIA/KLF2/TNFSF13B/CARD16/TNFRSF1B/CCL3/CASP1/PTGS2/TNFAIP3/GBP1/STAT1/CXCL8/GBP2/JAK2/SYK/TNF/TNFRSF14/BIRC3/GCH1/CCL4/PTK2B/ZFP36L1/HSPA1A/TNFRSF1A/CYLD/LIMS1/ADAM10/CARD8/MAPK1/ASAH1/TANK/PTPN2/HIPK1/ADAM17/NFKB1/BIRC2/CIB1	45
GO:0043299	leukocyte degranulation	24/896	73/18722	1.94913024255761e-14	1.15198027176615e-12	ITGB2/CORO1A/CCL3/STXBP2/SPI1/LYN/FGR/HCK/RAC2/LGALS9/HLA-F/NCKAP1L/SYK/CCR2/LAT2/PRAM1/ITGAM/RAB27A/ADGRE2/PTAFR/CD300A/BTK/CD84/HMOX1	24
GO:0071674	mononuclear cell migration	39/896	196/18722	2.36378718269529e-14	1.38135473451665e-12	AIF1/DUSP1/S100A12/CCL3L3/PYCARD/CCL3/JAML/SPI1/C5AR1/MSN/LYN/PECAM1/ITGA4/CX3CR1/CCR1/LGALS9/ITGAL/MYO1G/CCR2/CSF1R/CXCR4/TNF/TNFRSF14/ALOX5/RHOA/IL6R/SPN/CCL4/PTK2B/STK10/CKLF/CDC42/DOCK8/SIRPA/ADAM10/MAPK1/ADAM17/PLEC/WNK1	39
GO:0050870	positive regulation of T cell activation	41/896	216/18722	2.74517595187153e-14	1.58640668063154e-12	AIF1/IL1B/PTPRC/HLA-A/HLA-DRA/CD74/PYCARD/CORO1A/LGALS1/TNFSF13B/HLA-DPA1/B2M/NFKBIZ/HLA-DPB1/LYN/HLA-DRB1/HLA-E/LILRB2/HLA-DQB1/HLA-DMA/HLA-DMB/CD83/PTPN6/LILRB1/LGALS9/CD4/NCKAP1L/SYK/CD86/NLRP3/CCR2/CSK/TNFRSF14/RHOA/HLA-DQA1/FYN/BCL6/DOCK8/SIRPA/MAP3K8/TGFBR2	41
GO:0002886	regulation of myeloid leukocyte mediated immunity	21/896	56/18722	4.13774091318738e-14	2.36487807576786e-12	TYROBP/ITGB2/STXBP2/SPI1/LYN/FGR/HLA-E/RAC2/CX3CR1/LGALS9/SYK/CCR2/PRAM1/ITGAM/ADGRE2/PTAFR/CD300A/BTK/CD84/HMOX1/DDX21	21
GO:0072593	reactive oxygen species metabolic process	43/896	239/18722	4.57903509383782e-14	2.58864799163593e-12	TYROBP/CYBB/CYBA/ITGB2/NCF1/TSPO/SOD2/NCF2/LRRK2/CLEC7A/CD36/GNAI2/CYP1B1/RAC2/GPX1/TGFB1/SYK/BST1/TNF/ITGAM/ALOX5/RHOA/TLR4/RAB27A/NCF4/FYN/HVCN1/GCH1/PREX1/PTK2B/CYB5R4/PDK4/G6PD/GRB2/CDKN1A/STAT3/CFLAR/HIF1A/PRCP/TGFBR2/NQO2/GNAI3/BIRC2	43
GO:0048872	homeostasis of number of cells	46/896	272/18722	6.32822804444258e-14	3.5390445224888e-12	ZFP36/CD74/CORO1A/KLF2/TNFSF13B/B2M/TSC22D3/SPI1/LYN/ISG15/TNFAIP3/STAT1/MAFB/MEF2C/JAK2/CX3CR1/LGALS9/NCKAP1L/CCR2/RASSF2/TCIRG1/IKZF1/GAPT/DOCK11/INPP5D/SH2B3/BCL6/ZFP36L1/HSPA1A/HCLS1/PKN1/G6PD/SKIL/KMT2E/PTBP3/STAT3/LIPA/RB1/HIF1A/ARID4A/ADAR/ZBTB7A/HMOX1/PTPN2/ADAM17/SP3	46
GO:0002444	myeloid leukocyte mediated immunity	27/896	99/18722	8.08862362836733e-14	4.47541824373814e-12	TYROBP/ITGB2/CCL3/STXBP2/SPI1/LYN/FGR/HLA-E/RAC2/CX3CR1/LGALS9/SYK/CCR2/LAT2/PRAM1/TREM1/MYD88/ITGAM/ADGRE2/PTAFR/CD300A/BTK/CD84/KMT2E/HMOX1/ADAM17/DDX21	27
GO:2000377	regulation of reactive oxygen species metabolic process	34/896	157/18722	8.32896710105626e-14	4.55989030448354e-12	TYROBP/CYBA/ITGB2/TSPO/SOD2/CLEC7A/CD36/GNAI2/CYP1B1/RAC2/TGFB1/SYK/BST1/TNF/ITGAM/ALOX5/RHOA/TLR4/RAB27A/FYN/HVCN1/GCH1/PTK2B/G6PD/GRB2/CDKN1A/STAT3/CFLAR/HIF1A/PRCP/TGFBR2/NQO2/GNAI3/BIRC2	34
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	37/896	186/18722	1.10875074386448e-13	6.00688814462414e-12	S100A4/S100A12/CD74/LGALS1/CARD16/TNFSF10/CLEC7A/FLNA/CD36/HLA-DRB1/CASP1/BST2/MTDH/SECTM1/LGALS9/PRKCB/TRIM22/CD4/TNF/MYD88/RHOA/TLR4/BIRC3/FYN/MAP3K3/AKAP13/FKBP1A/TRIM38/REL/LITAF/TNFRSF1A/CFLAR/HMOX1/LTBR/DDX21/NUP62/BIRC2	37
GO:0002832	negative regulation of response to biotic stimulus	28/896	108/18722	1.12890287391338e-13	6.05301427548811e-12	FGL2/HLA-B/HLA-A/SAMHD1/CARD16/IFI16/ISG15/TNFAIP3/HLA-E/ARRB2/IRAK3/USP15/LILRB1/LGALS9/GRN/HLA-F/STAT2/OAS1/LILRA2/AHR/PARP14/TRIB1/CARD8/ADAR/PCBP2/SEC14L1/PTPN2/NMI	28
GO:0060326	cell chemotaxis	49/896	310/18722	1.38483600372775e-13	7.34952250549796e-12	S100A9/S100A8/AIF1/FCER1G/ITGB2/TMSB4X/DUSP1/S100A12/CCL3L3/CD74/CORO1A/CCL3/JAML/SPI1/C5AR1/LYN/LYST/GPSM3/ARRB2/CXCL8/RAC2/NR4A1/CX3CR1/CCR1/LGALS9/NCKAP1L/SYK/CCR2/BST1/HBEGF/CSF1R/CXCR4/TREM1/ALOX5/IL6R/RIN3/ADGRE2/CCL4/PREX1/PTK2B/RHOG/CKLF/BIN2/ADAM10/MAPK1/ADAM17/PLEC/NINJ1/WNK1	49
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	53/896	356/18722	1.65164336826546e-13	8.59272065897936e-12	IL1B/FCER1G/HLA-B/PTPRC/HLA-A/HLA-DRA/CD74/TNFSF13B/TNFRSF1B/HLA-DPA1/B2M/NFKBIZ/CLEC7A/HLA-DPB1/SLC11A1/HLA-DRB1/TNFAIP3/HLA-E/WAS/HLA-DQB1/HLA-DMA/HLA-DMB/MEF2C/PTPN6/LILRB1/HLA-F/CTSH/CD4/NCKAP1L/TGFB1/MYO1G/NLRP3/CCR2/TLR8/TNF/MYD88/TCIRG1/STAT6/IL6R/TLR4/GAPT/RAB27A/HLA-DQA1/IRF7/SPN/INPP5D/BCL6/BTK/AHR/PKN1/STAT3/ADAM17/STX7	53
GO:0031348	negative regulation of defense response	44/896	258/18722	1.6521285635415e-13	8.59272065897936e-12	FGL2/ZFP36/HLA-B/PTPRC/HLA-A/SAMHD1/TNFRSF1B/LYN/KLF4/IFI16/FGR/ISG15/HLA-DRB1/TNFAIP3/HLA-E/HCK/ARRB2/IRAK3/SOCS3/USP15/AOAH/LILRB1/GPX1/LGALS9/GRN/HLA-F/SYK/NLRP3/STAT2/OAS1/ALOX5/FYN/TNFAIP8L2/METRNL/PARP14/TNFRSF1A/SIRPA/RB1/ADAR/PCBP2/SEC14L1/PTPN2/NMI/NFKB1	44
GO:0032611	interleukin-1 beta production	28/896	110/18722	1.85941811741757e-13	9.48120943989098e-12	MNDA/TYROBP/PYCARD/CARD16/CCL3/CLEC7A/EGR1/IFI16/CD36/CASP1/TNFAIP3/ARRB2/JAK2/CX3CR1/LGALS9/GBP5/NLRP3/TLR8/LILRA5/LILRA2/TNF/MYD88/TLR4/CD33/SERPINB1/STAT3/SIRPA/CARD8	28
GO:0032651	regulation of interleukin-1 beta production	28/896	110/18722	1.85941811741757e-13	9.48120943989098e-12	MNDA/TYROBP/PYCARD/CARD16/CCL3/CLEC7A/EGR1/IFI16/CD36/CASP1/TNFAIP3/ARRB2/JAK2/CX3CR1/LGALS9/GBP5/NLRP3/TLR8/LILRA5/LILRA2/TNF/MYD88/TLR4/CD33/SERPINB1/STAT3/SIRPA/CARD8	28
GO:0002429	immune response-activating cell surface receptor signaling pathway	47/896	291/18722	1.9535066577179e-13	9.76941166037575e-12	FCN1/MNDA/TYROBP/FCER1G/PTPRC/HLA-A/LAPTM5/FPR1/C5AR1/NFKBIZ/CLEC7A/HLA-DPB1/LYN/FGR/HLA-DRB1/GBP1/HCK/HLA-DQB1/MEF2C/THEMIS2/PTPN6/PRKCB/NCKAP1L/SYK/MYO1G/PLSCR1/LAT2/PRAM1/CSK/LCP2/LILRA2/NFAM1/FYN/CD300A/INPP5D/BTK/CMTM3/RAP1A/PAK1/PAK2/MAPK1/DGKZ/PTPN2/PRNP/CREBBP/EP300/WNK1	47
GO:0002757	immune response-activating signal transduction	47/896	291/18722	1.9535066577179e-13	9.76941166037575e-12	FCN1/MNDA/TYROBP/FCER1G/PTPRC/HLA-A/LAPTM5/FPR1/C5AR1/NFKBIZ/CLEC7A/HLA-DPB1/LYN/FGR/HLA-DRB1/GBP1/HCK/HLA-DQB1/MEF2C/THEMIS2/PTPN6/PRKCB/NCKAP1L/SYK/MYO1G/PLSCR1/LAT2/PRAM1/CSK/LCP2/LILRA2/NFAM1/FYN/CD300A/INPP5D/BTK/CMTM3/RAP1A/PAK1/PAK2/MAPK1/DGKZ/PTPN2/PRNP/CREBBP/EP300/WNK1	47
GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	43/896	249/18722	2.00350278636412e-13	9.92401713512363e-12	S100A4/IL1B/S100A12/CD74/PYCARD/LGALS1/CARD16/TNFSF10/CLEC7A/FLNA/CD36/HLA-DRB1/CASP1/TNFAIP3/STAT1/BST2/MTDH/SECTM1/LGALS9/PRKCB/TRIM22/CD4/TNF/MYD88/RHOA/TLR4/BIRC3/FYN/MAP3K3/AKAP13/FKBP1A/TRIM38/REL/LITAF/TNFRSF1A/CFLAR/CARD8/TANK/HMOX1/LTBR/DDX21/NUP62/BIRC2	43
GO:0071356	cellular response to tumor necrosis factor	41/896	229/18722	2.12338823382406e-13	1.04186247208669e-11	CYBA/ZFP36/TMSB4X/CCL3L3/LAPTM5/ZFP36L2/PYCARD/NFKBIA/KLF2/TNFSF13B/CARD16/TNFRSF1B/CCL3/CASP1/TNFAIP3/GBP1/STAT1/CXCL8/GBP2/JAK2/SYK/TNF/TNFRSF14/BIRC3/CCL4/PTK2B/ZFP36L1/HSPA1A/TNFRSF1A/CYLD/LIMS1/CARD8/MAPK1/ASAH1/TANK/PTPN2/HIPK1/ADAM17/NFKB1/BIRC2/CIB1	41
GO:0002685	regulation of leukocyte migration	39/896	210/18722	2.44835161723077e-13	1.19008194030067e-11	AIF1/DUSP1/CD74/PYCARD/CCL3/SPI1/C5AR1/MSN/LYN/GPSM3/CXCL8/RAC2/ITGA4/CX3CR1/CCR1/LGALS9/NCKAP1L/CCR2/BST1/CSF1R/TNF/MYD88/TNFRSF14/RHOA/IL6R/RIN3/PTAFR/CD300A/SPN/CCL4/PTK2B/RHOG/STK10/DOCK8/ADAM10/MAPK1/HMOX1/ADAM17/WNK1	39
GO:0036230	granulocyte activation	18/896	43/18722	2.87650733212134e-13	1.38525135503362e-11	TYROBP/FCER1G/ITGB2/CCL3/STXBP2/SPI1/CXCL8/GRN/SYK/CCR2/PRAM1/LILRA2/MYD88/ITGAM/PTAFR/CD300A/PREX1/KMT2E	18
GO:0032731	positive regulation of interleukin-1 beta production	21/896	62/18722	4.30308145417993e-13	2.05324097643943e-11	MNDA/TYROBP/PYCARD/CCL3/CLEC7A/EGR1/IFI16/CD36/CASP1/JAK2/LGALS9/GBP5/NLRP3/TLR8/LILRA5/LILRA2/TNF/MYD88/TLR4/STAT3/CARD8	21
GO:0051250	negative regulation of lymphocyte activation	33/896	157/18722	4.72195558756363e-13	2.23262645553804e-11	MNDA/FGL2/LST1/TYROBP/LAPTM5/CD74/IRF1/LYN/FGR/HLA-DRB1/TNFAIP3/LILRB2/CEBPB/PTPN6/LILRB1/LGALS9/HLA-F/NCKAP1L/CD86/TNFRSF14/CD300A/SPN/PAG1/INPP5D/BCL6/TNFAIP8L2/BTK/SAMSN1/PKN1/PRKAR1A/ATM/PTPN2/PRNP	33
GO:0042116	macrophage activation	27/896	106/18722	4.93495000193972e-13	2.31231305946743e-11	AIF1/TYROBP/ITGB2/PTPRC/CD74/NAMPT/CCL3/C5AR1/LRRK2/SLC11A1/IFNGR2/JAK2/CX3CR1/CD93/GRN/TLR2/SYK/TNF/ITGAM/TLR4/TLR1/IFI35/JUND/CD84/IFNGR1/PJA2/NMI	27
GO:0030183	B cell differentiation	31/896	141/18722	6.79959736622784e-13	3.15756302694205e-11	PTPRC/ZFP36L2/LGALS1/TNFSF13B/KLF6/SPI1/ITGA4/PTPN6/NCKAP1L/SYK/NOTCH2/LFNG/TCIRG1/NFAM1/DOCK11/HHEX/LYL1/INPP5D/BCL6/BTK/IRF8/PTK2B/ZFP36L1/CMTM7/ATM/ZBTB7A/PTPN2/ADAM17/EP300/IRF2BP2/SP3	31
GO:0071900	regulation of protein serine/threonine kinase activity	52/896	359/18722	8.41576016138357e-13	3.87348394684566e-11	IL1B/DUSP1/RGS2/S100A12/PYCARD/LRRK2/LYN/ACTB/TNFAIP3/IRAK3/DAZAP2/PTPN6/CCNL1/IQGAP1/TGFB1/SYK/SORL1/SLC8A1/CSF1R/CSK/TNF/RHOA/TLR4/FGD2/CD300A/HHEX/SH2B3/ACSL1/PTK2B/AKAP13/CALM2/RALB/TRIB1/STK4/PRKAG2/PAK1/TAOK3/CCNI/CDKN1A/PRKAR1A/CCNY/STK38/PTEN/HIPK3/RB1/MAP3K11/CAB39/TAOK1/ADAM17/DDX3X/NUP62/CIB1	52
GO:0032722	positive regulation of chemokine production	22/896	71/18722	9.42008549978914e-13	4.29770742845643e-11	AIF1/IL1B/CD74/PYCARD/CLEC7A/EGR1/IL17RA/LGALS9/TLR2/SYK/CSF1R/OAS1/TNF/MYD88/IL6R/TLR4/MBP/CD84/HIF1A/HMOX1/ADAM17/DDX3X	22
GO:0043300	regulation of leukocyte degranulation	18/896	46/18722	1.16321632752205e-12	5.2607722777758e-11	ITGB2/STXBP2/SPI1/LYN/FGR/RAC2/LGALS9/HLA-F/NCKAP1L/SYK/CCR2/PRAM1/ITGAM/ADGRE2/PTAFR/CD300A/CD84/HMOX1	18
GO:0060759	regulation of response to cytokine stimulus	33/896	162/18722	1.19163127198065e-12	5.34282262549257e-11	PTPRC/LAPTM5/SAMHD1/CD74/PYCARD/CARD16/KLF4/ISG15/CASP1/TNFAIP3/IRAK3/PTPN6/IL1RN/TLR2/SYK/STAT2/CXCR4/OAS1/TLR4/PARP9/CD300LF/IRF7/SH2B3/HSPA1A/PARP14/CYLD/HIF1A/CARD8/IFIH1/ADAR/PTPN2/HIPK1/ADAM17	33
GO:0002253	activation of immune response	53/896	375/18722	1.35299311759202e-12	6.01445914922741e-11	FCN1/MNDA/TYROBP/IL1B/FCER1G/PTPRC/HLA-A/LAPTM5/PYCARD/CFD/FPR1/CFP/C5AR1/NFKBIZ/CLEC7A/HLA-DPB1/LYN/IFI16/FGR/HLA-DRB1/GBP1/HCK/HLA-DQB1/MEF2C/THEMIS2/PTPN6/PRKCB/NCKAP1L/SYK/MYO1G/PLSCR1/LAT2/PRAM1/CSK/LCP2/LILRA2/TLR4/NFAM1/FYN/CD300A/INPP5D/BTK/CMTM3/RAP1A/PAK1/PAK2/MAPK1/DGKZ/PTPN2/PRNP/CREBBP/EP300/WNK1	53
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	43/896	264/18722	1.57105802242049e-12	6.92463794458387e-11	ITGB2/NCF1/PTPRC/CD74/CD44/CLEC7A/LYN/CD36/ARRB2/SOCS3/FCGR1A/PECAM1/PTPN6/JAK2/IQGAP1/CD4/TGFB1/SYK/BST1/HBEGF/CSF1R/LILRA5/TNF/TNFRSF14/IL6R/PARP9/FYN/CD300A/SH2B3/PTK2B/SAMSN1/HCLS1/PARP14/ITGA5/PAK2/TNFRSF1A/DUSP22/PTPN2/ABI1/RAP2B/ADAM17/MVP/PRNP	43
GO:0050764	regulation of phagocytosis	25/896	95/18722	1.62983410541685e-12	7.10119494090303e-11	IL1B/CYBA/FCER1G/PTPRC/PYCARD/CLEC7A/SLC11A1/CD36/FGR/HCK/TLR2/NCKAP1L/SYK/DOCK2/PLSCR1/CSK/TNF/CD300LF/RAB27A/CD300A/CNN2/RAP1A/ATG3/SIRPA/PTEN	25
GO:0001933	negative regulation of protein phosphorylation	50/896	342/18722	1.63842221285977e-12	7.10119494090303e-11	IL1B/DUSP1/PTPRC/RGS2/PYCARD/DUSP6/LRRK2/GADD45B/LYN/TNFAIP3/ARRB2/IRAK3/SOCS3/PTPN6/MYADM/TGFB1/SORL1/SLC8A1/RASSF2/CD300A/HHEX/SH2B3/SAMSN1/PARP14/CALM2/TRIB1/PKN1/CHP1/C9orf72/PRKAG2/PAK2/CDKN1A/PRKAR1A/GNAQ/SIRPA/STK38/PTEN/HIPK3/RB1/ADAR/PPP1R15B/CORO1C/DUSP22/PTPN2/MVP/PRNP/PLEC/NUP62/CTDSP1/CIB1	50
GO:0002761	regulation of myeloid leukocyte differentiation	28/896	120/18722	1.8929647201297e-12	8.0699258273726e-11	TYROBP/FOS/EVI2B/CD74/CCL3/LYN/HLA-DRB1/LILRB3/MAFB/CEBPB/LILRB1/CCR1/CD4/TGFB1/NOTCH2/RASSF2/TNF/TLR4/IRF7/INPP5D/JUN/ZFP36L1/HCLS1/TRIB1/RB1/KLF10/PTPN2/CREB1	28
GO:0030218	erythrocyte differentiation	28/896	120/18722	1.8929647201297e-12	8.0699258273726e-11	ZFP36/KLF2/B2M/SPI1/LYN/ISG15/STAT1/MAFB/JAK2/NCKAP1L/IKZF1/INPP5D/SH2B3/BCL6/ZFP36L1/HSPA1A/HCLS1/G6PD/KMT2E/PTBP3/STAT3/RB1/HIF1A/ARID4A/ADAR/ZBTB7A/PTPN2/SP3	28
GO:0042119	neutrophil activation	16/896	36/18722	1.96993251295161e-12	8.32977154460271e-11	TYROBP/FCER1G/ITGB2/STXBP2/SPI1/CXCL8/GRN/SYK/PRAM1/LILRA2/MYD88/ITGAM/PTAFR/CD300A/PREX1/KMT2E	16
GO:0034101	erythrocyte homeostasis	29/896	129/18722	2.07928566201907e-12	8.72126187754935e-11	ZFP36/KLF2/B2M/SPI1/LYN/ISG15/STAT1/MAFB/JAK2/NCKAP1L/IKZF1/INPP5D/SH2B3/BCL6/ZFP36L1/HSPA1A/HCLS1/G6PD/KMT2E/PTBP3/STAT3/RB1/HIF1A/ARID4A/ADAR/ZBTB7A/HMOX1/PTPN2/SP3	29
GO:1902107	positive regulation of leukocyte differentiation	32/896	157/18722	2.57576589969074e-12	1.06321892415012e-10	TYROBP/FOS/PTPRC/HLA-DRA/EVI2B/CD74/NFKBIZ/HLA-DRB1/LILRB2/CD83/CCR1/LGALS9/CD4/NCKAP1L/TGFB1/SYK/NOTCH2/CD86/NLRP3/TNF/RHOA/INPP5D/BCL6/BTK/JUN/ZFP36L1/HCLS1/TRIB1/RB1/KLF10/TGFBR2/CREB1	32
GO:1903708	positive regulation of hemopoiesis	32/896	157/18722	2.57576589969074e-12	1.06321892415012e-10	TYROBP/FOS/PTPRC/HLA-DRA/EVI2B/CD74/NFKBIZ/HLA-DRB1/LILRB2/CD83/CCR1/LGALS9/CD4/NCKAP1L/TGFB1/SYK/NOTCH2/CD86/NLRP3/TNF/RHOA/INPP5D/BCL6/BTK/JUN/ZFP36L1/HCLS1/TRIB1/RB1/KLF10/TGFBR2/CREB1	32
GO:0033673	negative regulation of kinase activity	40/896	237/18722	2.98196585210259e-12	1.22119719659729e-10	IL1B/DUSP1/PTPRC/RGS2/PYCARD/GADD45B/LYN/TNFAIP3/IRAK3/PTPN6/SORL1/SLC8A1/CSK/CD300A/HHEX/SH2B3/MIDN/TRIB1/PKN1/CHP1/PRKAG2/PAK2/CDKN1A/PRKAR1A/GNAQ/STK38/PTEN/HIPK3/RB1/ADAR/PIP4K2A/CORO1C/HNRNPU/IRS2/DUSP22/PTPN2/MVP/PLEC/NUP62/WNK1	40
GO:0007162	negative regulation of cell adhesion	46/896	303/18722	3.38572635890209e-12	1.37571584317576e-10	FGL2/DUSP1/PTPRC/LAPTM5/CD74/LGALS1/IRF1/ARHGDIB/SPI1/FXYD5/KLF4/HLA-DRB1/GBP1/LILRB2/CYP1B1/CEBPB/PTPN6/LILRB1/JAK2/LGALS9/IL1RN/MYADM/TGFBI/NCKAP1L/TGFB1/CD86/PLXNC1/TNFRSF14/RHOA/MBP/CD300A/SPN/PAG1/SH2B3/BCL6/TNFAIP8L2/PRKAR1A/PTEN/ADAM10/PLXNB2/CORO1C/DUSP22/PTPN2/PRNP/ARHGDIA/WNK1	46
GO:0002833	positive regulation of response to biotic stimulus	33/896	168/18722	3.43703376031915e-12	1.38573740987751e-10	FCN1/MNDA/TYROBP/CYBA/PYCARD/SPI1/CLEC7A/LYN/IFI16/HLA-DRB1/HLA-E/HCK/SCIMP/USP15/LY86/GRN/HLA-F/LY96/GBP5/SYK/PLSCR1/TLR8/LILRA2/TLR4/PARP9/FYN/IRF7/IFI35/PAK1/PAK2/NMI/CREBBP/EP300	33
GO:0002367	cytokine production involved in immune response	25/896	98/18722	3.47464004608073e-12	1.39012329843584e-10	IL1B/HLA-A/LAPTM5/CD74/TNFRSF1B/B2M/CLEC7A/CD36/HLA-E/BST2/SCIMP/IRAK3/LILRB1/HLA-F/TGFB1/NLRP3/CCR2/TREM1/TNF/TNFRSF14/TLR4/BCL6/BTK/HMOX1/DDX21	25
GO:0045860	positive regulation of protein kinase activity	53/896	386/18722	4.247542089945e-12	1.68637148166442e-10	IL1B/NCF1/PTPRC/S100A12/LRRK2/SLC11A1/EGR1/FCGR1A/DAZAP2/JAK2/IQGAP1/CD4/NCKAP1L/TGFB1/SYK/CD86/HBEGF/CCDC88A/CSF1R/CSK/LILRA5/LCP2/RASSF2/TNF/RHOA/IL6R/TLR4/FGD2/CD300A/ACSL1/PTK2B/AKAP13/OSBPL8/CALM2/RALB/STK4/RAP1A/PRKAG2/PAK1/TAOK3/PAK2/CDKN1A/CCNY/MAP3K11/TGFBR2/CAB39/ABI1/TAOK1/ADAM17/DDX3X/PRNP/WNK1/CIB1	53
GO:0032602	chemokine production	25/896	99/18722	4.4407045986158e-12	1.73654921935344e-10	AIF1/IL1B/CD74/PYCARD/CLEC7A/EGR1/KLF4/IL17RA/LGALS9/TLR2/SYK/CSF1R/TREM1/OAS1/TNF/MYD88/IL6R/TLR4/MBP/CD84/SIRPA/HIF1A/HMOX1/ADAM17/DDX3X	25
GO:0033209	tumor necrosis factor-mediated signaling pathway	25/896	99/18722	4.4407045986158e-12	1.73654921935344e-10	TMSB4X/LAPTM5/PYCARD/NFKBIA/TNFSF13B/CARD16/TNFRSF1B/CASP1/TNFAIP3/STAT1/JAK2/SYK/TNF/TNFRSF14/BIRC3/PTK2B/HSPA1A/TNFRSF1A/CYLD/LIMS1/CARD8/PTPN2/HIPK1/ADAM17/BIRC2	25
GO:0030833	regulation of actin filament polymerization	33/896	171/18722	5.72288356304074e-12	2.22124756801305e-10	TMSB4X/COTL1/PYCARD/CORO1A/GMFG/HCK/ACTR2/WAS/TMSB10/VASP/MYADM/NCKAP1L/ARPC1B/ARPC3/CAPG/RHOA/PREX1/PTK2B/HCLS1/ACTR3/CDC42EP3/ARPC4/CAPZA1/MTPN/CAPZA2/GRB2/TWF2/PFN1/DBNL/ARPC5/FLII/SSH2/BRK1	33
GO:0016032	viral process	55/896	415/18722	6.9024756382945e-12	2.65924265146442e-10	FCN1/ZFP36/APOBEC3A/CD74/IFITM3/LGALS1/CCL3/IFI16/ISG15/PABPC1/HLA-DRB1/STAT1/BST2/CXCL8/MX1/IFITM2/LGALS9/TRIM22/CD4/CD86/PLSCR1/CXCR4/SELPLG/OAS1/OAS2/TNF/TNFRSF14/PARP9/ATG16L2/IRF7/CCL4/JUN/CTSB/HSPA1A/TRIM38/CFL1/ITGA5/FAM111A/CDC42/DDX5/CHD1/MGAT1/RXRA/CTBP2/IFIH1/ADAR/PCBP2/CALCOCO2/DYNLT1/SP1/DDX3X/SPCS3/CHMP1B/EP300/USF2	55
GO:0002687	positive regulation of leukocyte migration	29/896	135/18722	6.95504731121364e-12	2.65979419600163e-10	AIF1/CD74/PYCARD/CCL3/SPI1/C5AR1/GPSM3/CXCL8/RAC2/ITGA4/CX3CR1/CCR1/LGALS9/NCKAP1L/CCR2/CSF1R/TNF/TNFRSF14/RHOA/IL6R/PTAFR/SPN/CCL4/PTK2B/DOCK8/ADAM10/MAPK1/ADAM17/WNK1	29
GO:0110053	regulation of actin filament organization	43/896	277/18722	8.18206549097766e-12	3.10619873128283e-10	TMSB4X/COTL1/PYCARD/CORO1A/GMFG/PLEK/FLNA/HCK/ACTR2/WAS/TMSB10/VASP/MYADM/NCKAP1L/ARPC1B/ARPC3/CCDC88A/CAPG/RHOA/GPR65/PREX1/PTK2B/HCLS1/ACTR3/ARAP1/CDC42EP3/ARPC4/CAPZA1/C9orf72/PAK1/MTPN/CAPZA2/PAK2/GRB2/TWF2/CDC42/ROCK1/PFN1/DBNL/ARPC5/FLII/SSH2/BRK1	43
GO:0001818	negative regulation of cytokine production	50/896	357/18722	8.32274508764043e-12	3.13670994208825e-10	TYROBP/SRGN/TSPO/ZFP36/TMSB4X/PTPRC/LAPTM5/PYCARD/KLF2/CARD16/SLC11A1/KLF4/HLA-DRB1/TNFAIP3/GBP1/BST2/ARRB2/IRAK3/CD83/PTPN6/LILRB1/CX3CR1/LGALS9/HLA-F/CLEC4A/NCKAP1L/TGFB1/NLRP3/TLR8/CSK/LILRA5/OAS1/TNF/TLR4/CD33/INPP5D/BCL6/BTK/REL/SERPINB1/CD84/SIRPA/CYLD/ADCY7/CARD8/HMOX1/DICER1/NMI/PRNP/NFKB1	50
GO:0033674	positive regulation of kinase activity	59/896	467/18722	8.75008593868095e-12	3.27404294727191e-10	IL1B/NCF1/PTPRC/S100A12/CD74/LRRK2/SLC11A1/EGR1/LYN/FGR/HLA-DRB1/FCGR1A/DAZAP2/JAK2/IQGAP1/CD4/NCKAP1L/TGFB1/SYK/CD86/HBEGF/CCDC88A/CSF1R/CSK/LILRA5/LCP2/RASSF2/TNF/RHOA/IL6R/TLR4/FGD2/CD300A/ACSL1/PTK2B/AKAP13/OSBPL8/CALM2/RALB/STK4/RAP1A/PRKAG2/PAK1/TAOK3/PAK2/CDKN1A/CDC42/CCNY/MAP3K11/DGKZ/TGFBR2/CAB39/ABI1/TAOK1/ADAM17/DDX3X/PRNP/WNK1/CIB1	59
GO:0043410	positive regulation of MAPK cascade	60/896	480/18722	9.08125130449869e-12	3.37368485962126e-10	IL1B/NCF1/PTPRC/S100A12/CCL3L3/LAPTM5/CD74/PYCARD/CD44/CCL3/SPI1/C5AR1/LRRK2/GADD45B/CLEC7A/CD36/HLA-DRB1/GNAI2/ARRB2/SCIMP/GLIPR2/CCR1/LGALS9/IQGAP1/CD4/TGFB1/SYK/NOTCH2/CSF1R/CSK/LILRA5/RASSF2/TNF/MYD88/GPBAR1/TLR4/FGD2/CCL4/MAP3K3/PTK2B/AKAP13/TIMP2/RAP1A/PAK1/TAOK3/CDC42/CFLAR/ROCK1/SDCBP/PTEN/RAP1B/MAP3K11/PJA2/NQO2/LAMTOR1/DUSP22/LTBR/TAOK1/RB1CC1/CIB1	60
GO:0002285	lymphocyte activation involved in immune response	35/896	194/18722	9.83734292140558e-12	3.6286539385979e-10	FGL2/FCER1G/LCP1/PTPRC/HLA-DRA/CD74/CORO1A/LGALS1/SPI1/NFKBIZ/SLC11A1/HLA-DRB1/HLA-DMB/LILRB1/LGALS9/HLA-F/ITGAL/NCKAP1L/TGFB1/NOTCH2/CD86/NLRP3/LFNG/APBB1IP/STAT6/IL6R/TLR4/GAPT/RAB27A/DOCK11/SPN/BCL6/IRF8/PTK2B/STAT3	35
GO:0032612	interleukin-1 production	28/896	128/18722	1.00815428275425e-11	3.66672057664676e-10	MNDA/TYROBP/PYCARD/CARD16/CCL3/CLEC7A/EGR1/IFI16/CD36/CASP1/TNFAIP3/ARRB2/JAK2/CX3CR1/LGALS9/GBP5/NLRP3/TLR8/LILRA5/LILRA2/TNF/MYD88/TLR4/CD33/SERPINB1/STAT3/SIRPA/CARD8	28
GO:0032652	regulation of interleukin-1 production	28/896	128/18722	1.00815428275425e-11	3.66672057664676e-10	MNDA/TYROBP/PYCARD/CARD16/CCL3/CLEC7A/EGR1/IFI16/CD36/CASP1/TNFAIP3/ARRB2/JAK2/CX3CR1/LGALS9/GBP5/NLRP3/TLR8/LILRA5/LILRA2/TNF/MYD88/TLR4/CD33/SERPINB1/STAT3/SIRPA/CARD8	28
GO:0051348	negative regulation of transferase activity	42/896	268/18722	1.04637466837718e-11	3.7793018404373e-10	IL1B/ZFP36/DUSP1/PTPRC/RGS2/PYCARD/GADD45B/LYN/TNFAIP3/IRAK3/PTPN6/SORL1/SLC8A1/CSK/CD300A/HHEX/SH2B3/MIDN/TRIB1/PKN1/DTX3L/CHP1/PRKAG2/PAK2/CDKN1A/PRKAR1A/GNAQ/STK38/PTEN/HIPK3/RB1/ADAR/PIP4K2A/CORO1C/HNRNPU/IRS2/DUSP22/PTPN2/MVP/PLEC/NUP62/WNK1	42
GO:0031334	positive regulation of protein-containing complex assembly	39/896	237/18722	1.25084716490794e-11	4.48665938254221e-10	LCP1/PYCARD/CORO1A/GMFG/MSN/PLEK/CLEC7A/CD36/ISG15/HCK/ACTR2/WAS/VASP/GBP5/NCKAP1L/TGFB1/SYK/ARPC1B/ARPC3/BID/TNF/MYD88/RHOA/TLR4/PTK2B/HSPA1A/ACTR3/CDC42EP3/ARPC4/NIN/PAK1/GRB2/PFN1/RAP1B/ARPC5/ATM/BRK1/DDX3X/CREB1	39
GO:0042060	wound healing	55/896	422/18722	1.34152376289382e-11	4.77894869233614e-10	S100A8/FCER1G/SERPINA1/CD44/JAML/TIMP1/PLEK/CLEC7A/SLC11A1/LYN/FLNA/CD36/ACTB/TNFAIP3/WAS/PLAUR/PTPN6/GPX1/JAK2/FERMT3/TGFB1/SYK/NOTCH2/PLSCR1/HBEGF/CXCR4/TNF/ALOX5/RHOA/TLR4/ENTPD1/RAB27A/SH2B3/CNN2/JMJD1C/ELK3/TLN1/ITGA5/PAK1/CDKN1A/CLIC1/GNAQ/CFLAR/PTEN/HIF1A/DGKZ/PRCP/HMOX1/TGFBR2/MYH9/PPP3CA/RAP2B/ADAM17/PLEC/BLOC1S6	55
GO:0002262	myeloid cell homeostasis	31/896	157/18722	1.3508232688902e-11	4.77934137516866e-10	ZFP36/KLF2/B2M/SPI1/LYN/ISG15/STAT1/MAFB/JAK2/NCKAP1L/CCR2/IKZF1/INPP5D/SH2B3/BCL6/ZFP36L1/HSPA1A/HCLS1/G6PD/KMT2E/PTBP3/STAT3/RB1/HIF1A/ARID4A/ADAR/ZBTB7A/HMOX1/PTPN2/ADAM17/SP3	31
GO:0002718	regulation of cytokine production involved in immune response	24/896	96/18722	1.50104722895378e-11	5.27496394445178e-10	IL1B/HLA-A/LAPTM5/CD74/TNFRSF1B/B2M/CLEC7A/CD36/HLA-E/BST2/SCIMP/IRAK3/LILRB1/HLA-F/TGFB1/NLRP3/CCR2/TNF/TNFRSF14/TLR4/BCL6/BTK/HMOX1/DDX21	24
GO:0032732	positive regulation of interleukin-1 production	21/896	73/18722	1.53559063503704e-11	5.36013885424674e-10	MNDA/TYROBP/PYCARD/CCL3/CLEC7A/EGR1/IFI16/CD36/CASP1/JAK2/LGALS9/GBP5/NLRP3/TLR8/LILRA5/LILRA2/TNF/MYD88/TLR4/STAT3/CARD8	21
GO:0008064	regulation of actin polymerization or depolymerization	34/896	187/18722	1.55646703093356e-11	5.3718443958012e-10	TMSB4X/COTL1/PYCARD/CORO1A/GMFG/PLEK/HCK/ACTR2/WAS/TMSB10/VASP/MYADM/NCKAP1L/ARPC1B/ARPC3/CAPG/RHOA/PREX1/PTK2B/HCLS1/ACTR3/CDC42EP3/ARPC4/CAPZA1/MTPN/CAPZA2/GRB2/TWF2/PFN1/DBNL/ARPC5/FLII/SSH2/BRK1	34
GO:0018108	peptidyl-tyrosine phosphorylation	51/896	375/18722	1.55960104550275e-11	5.3718443958012e-10	ITGB2/NCF1/PTPRC/CD74/CD44/CLEC7A/LYN/CD36/FGR/HCK/ARRB2/SOCS3/FCGR1A/PECAM1/PTPN6/JAK2/IQGAP1/CD4/TGFB1/SYK/BST1/HBEGF/CSF1R/CSK/LILRA5/TNF/TNFRSF14/IL6R/PARP9/FYN/CD300A/SH2B3/BTK/PTK2B/SAMSN1/JAK1/HCLS1/PARP14/ITGA5/PAK2/TNFRSF1A/HIPK3/CLK1/DUSP22/PTPN2/ABI1/HIPK1/RAP2B/ADAM17/MVP/PRNP	51
GO:0030832	regulation of actin filament length	34/896	188/18722	1.81490829240041e-11	6.2100908084043e-10	TMSB4X/COTL1/PYCARD/CORO1A/GMFG/PLEK/HCK/ACTR2/WAS/TMSB10/VASP/MYADM/NCKAP1L/ARPC1B/ARPC3/CAPG/RHOA/PREX1/PTK2B/HCLS1/ACTR3/CDC42EP3/ARPC4/CAPZA1/MTPN/CAPZA2/GRB2/TWF2/PFN1/DBNL/ARPC5/FLII/SSH2/BRK1	34
GO:0070371	ERK1 and ERK2 cascade	47/896	330/18722	1.96647969031203e-11	6.68474566621757e-10	IL1B/DUSP1/PTPRC/CCL3L3/ZFP36L2/CD74/PYCARD/CD44/CCL3/DUSP6/C5AR1/LYN/KLF4/CD36/HLA-DRB1/GNAI2/GBP1/ARRB2/SCIMP/GLIPR2/PTPN6/CCR1/LGALS9/CTSH/CD4/TGFB1/SYK/NOTCH2/CSF1R/CSK/TNF/GPBAR1/TLR4/CCL4/PTK2B/ZFP36L1/RAP1A/RRAS/SIRPA/CFLAR/PTEN/MAPK1/RAP1B/ATF3/NQO2/PTPN2/CIB1	47
GO:0070665	positive regulation of leukocyte proliferation	30/896	150/18722	2.05738520210189e-11	6.9483509325532e-10	AIF1/IL1B/PTPRC/HLA-A/CD74/PYCARD/CORO1A/TNFSF13B/HLA-DPA1/HLA-DPB1/LYN/HLA-E/BST2/LILRB2/HLA-DMB/MEF2C/LGALS9/NCKAP1L/SYK/CD86/CCR2/BST1/CSF1R/MYD88/TLR4/BCL6/CDKN1A/MAPK1/TGFBR2/IRS2	30
GO:0042098	T cell proliferation	35/896	199/18722	2.07986813446072e-11	6.97896397892272e-10	AIF1/IL1B/PTPRC/HLA-A/PYCARD/CORO1A/TNFSF13B/TNFRSF1B/HLA-DPA1/IRF1/MSN/HLA-DPB1/SLC11A1/HLA-DRB1/HLA-E/LILRB2/HLA-DMB/RAC2/CEBPB/PTPN6/LILRB1/LGALS9/NCKAP1L/SYK/DOCK2/CD86/CCR2/TNFRSF14/FYN/SPN/PSMB10/PRKAR1A/DOCK8/TGFBR2/PRNP	35
GO:0018212	peptidyl-tyrosine modification	51/896	378/18722	2.10218552682745e-11	7.00863264424972e-10	ITGB2/NCF1/PTPRC/CD74/CD44/CLEC7A/LYN/CD36/FGR/HCK/ARRB2/SOCS3/FCGR1A/PECAM1/PTPN6/JAK2/IQGAP1/CD4/TGFB1/SYK/BST1/HBEGF/CSF1R/CSK/LILRA5/TNF/TNFRSF14/IL6R/PARP9/FYN/CD300A/SH2B3/BTK/PTK2B/SAMSN1/JAK1/HCLS1/PARP14/ITGA5/PAK2/TNFRSF1A/HIPK3/CLK1/DUSP22/PTPN2/ABI1/HIPK1/RAP2B/ADAM17/MVP/PRNP	51
GO:0097529	myeloid leukocyte migration	37/896	220/18722	2.18231203293832e-11	7.22942986198231e-10	S100A9/S100A8/AIF1/FCER1G/ITGB2/DUSP1/S100A12/CCL3L3/CD74/CCL3/JAML/SPI1/C5AR1/LYN/CXCL8/RAC2/PECAM1/CX3CR1/CCR1/NCKAP1L/SYK/CCR2/BST1/CSF1R/TREM1/MYD88/IL6R/RIN3/ADGRE2/CD300A/CCL4/PREX1/PTK2B/RHOG/CKLF/SIRPA/MAPK1	37
GO:0001774	microglial cell activation	17/896	47/18722	2.20504944827358e-11	7.25852036738665e-10	AIF1/TYROBP/ITGB2/PTPRC/NAMPT/CCL3/C5AR1/LRRK2/IFNGR2/JAK2/CX3CR1/GRN/TLR2/TNF/ITGAM/TLR1/IFNGR1	17
GO:0032642	regulation of chemokine production	24/896	98/18722	2.41076517736188e-11	7.88577967764726e-10	AIF1/IL1B/CD74/PYCARD/CLEC7A/EGR1/KLF4/IL17RA/LGALS9/TLR2/SYK/CSF1R/OAS1/TNF/MYD88/IL6R/TLR4/MBP/CD84/SIRPA/HIF1A/HMOX1/ADAM17/DDX3X	24
GO:0071675	regulation of mononuclear cell migration	26/896	115/18722	2.51030663617218e-11	8.16006550920718e-10	AIF1/DUSP1/PYCARD/CCL3/SPI1/C5AR1/MSN/LYN/ITGA4/CX3CR1/CCR1/LGALS9/CCR2/CSF1R/TNF/TNFRSF14/RHOA/SPN/CCL4/PTK2B/STK10/DOCK8/ADAM10/MAPK1/ADAM17/WNK1	26
GO:1902903	regulation of supramolecular fiber organization	51/896	382/18722	3.11204286313829e-11	1.00532515100511e-09	TMSB4X/COTL1/PYCARD/CORO1A/GMFG/PLEK/FLNA/HCK/ACTR2/WAS/TMSB10/GPX1/VASP/MYADM/NCKAP1L/ARPC1B/ARPC3/CCDC88A/CAPG/RHOA/PFDN5/GPR65/PREX1/PTK2B/AKAP13/HSPA1A/HCLS1/ACTR3/ARAP1/CDC42EP3/ARPC4/NIN/CAPZA1/C9orf72/PAK1/MTPN/CAPZA2/PAK2/GRB2/TWF2/CDC42/ROCK1/RB1/PFN1/DBNL/ARPC5/FLII/SSH2/BRK1/TAOK1/CIB1	51
GO:0052548	regulation of endopeptidase activity	55/896	432/18722	3.36374735149013e-11	1.07992901080865e-09	S100A9/S100A8/SERPINA1/CST3/LAPTM5/PYCARD/CD44/CARD16/CSTA/TIMP1/TNFSF10/PSMB9/CLEC7A/LYN/KLF4/IFI16/CASP1/PTGS2/BST2/ARRB2/PSMB8/NR4A1/NAIP/PLAUR/GPX1/JAK2/LGALS9/CTSH/SYK/NLRP3/SORL1/BID/TNF/RHOA/BIRC3/MBP/FYN/APAF1/PSME2/SERPINB1/TIMP2/PSME1/PICALM/RPS6KA3/PAK2/STAT3/CFLAR/CSTB/ROCK1/CAST/CARD8/DDX3X/PRNP/HERPUD1/BIRC2	55
GO:1901653	cellular response to peptide	49/896	359/18722	3.45462038198327e-11	1.10229942372362e-09	IL1B/CYBA/VIM/KLF2/NAMPT/LYN/KLF4/CD36/GNAI2/STAT1/SOCS3/NR4A1/AGTRAP/ITGA4/NR4A2/PTPRE/JAK2/UCP2/PRKCB/SORL1/CSK/STAT6/TLR4/FYN/ZFP36L1/OSBPL8/PDK4/RAB8B/RHOQ/PAK1/GRB2/STAT3/CFLAR/ROCK1/PTEN/ZNF106/KLF10/RAP1B/KLF3/PIP4K2A/IRS2/PHIP/RAB10/PTPN2/SP1/MAX/PRNP/NFKB1/CREB1	49
GO:0032102	negative regulation of response to external stimulus	54/896	420/18722	3.49832382090622e-11	1.1094379385691e-09	AIF1/FGL2/ZFP36/DUSP1/HLA-B/PTPRC/HLA-A/SAMHD1/CARD16/TNFRSF1B/LYN/KLF4/IFI16/FGR/ISG15/HLA-DRB1/TNFAIP3/HLA-E/HCK/ARRB2/IRAK3/SOCS3/USP15/AOAH/LILRB1/GPX1/LGALS9/GRN/HLA-F/SYK/NLRP3/STAT2/OAS1/LILRA2/TNF/ALOX5/RIN3/FYN/SH2B3/TNFAIP8L2/METRNL/PARP14/TRIB1/TNFRSF1A/SIRPA/PTEN/RB1/CARD8/ADAR/PCBP2/SEC14L1/PTPN2/NMI/NFKB1	54
GO:0007265	Ras protein signal transduction	47/896	337/18722	4.12411934778469e-11	1.29997240774716e-09	AIF1/ARHGDIB/RHOB/WAS/RAC2/DOK2/NOTCH2/RHOA/LPAR6/GPR65/DOK3/RASGRP2/BCL6/CYTH4/ARHGAP4/JUN/FBP1/RHOG/AKAP13/TIMP2/RALB/CDC42EP3/CYTH1/CFL1/GABARAP/RAP1A/SHTN1/GRB2/CDKN1A/CDC42/RRAS/ROCK1/SDCBP/RB1/RAP1B/ARHGEF3/DBNL/GNB1/BRK1/MYO9B/SHOC2/CDC42SE1/DYNLT1/RAP2B/ARHGDIA/NUP62/GNA13	47
GO:0070997	neuron death	49/896	361/18722	4.22150355823234e-11	1.32265301243171e-09	TYROBP/FOS/ITGB2/SOD2/CORO1A/TNFRSF1B/NAMPT/CCL3/MCL1/C5AR1/LRRK2/EGR1/BTG2/ARRB2/NAIP/MEF2C/CEBPB/NR4A2/GPX1/JAK2/CX3CR1/PPT1/GRN/HLA-F/CTSZ/SORL1/BID/TNF/ITGAM/RHOA/TLR4/FYN/JUN/PTK2B/REL/CAPN2/G6PD/CHP1/PICALM/CDC42/STAT3/RB1/HIF1A/MAP3K11/HMOX1/NQO2/MAX/PRNP/CREB1	49
GO:0052547	regulation of peptidase activity	57/896	461/18722	4.71620989071117e-11	1.46880285278975e-09	S100A9/S100A8/SERPINA1/CST3/LAPTM5/PYCARD/CD44/CARD16/CSTA/TIMP1/TNFSF10/PSMB9/CLEC7A/LYN/KLF4/IFI16/CASP1/PTGS2/BST2/ARRB2/PSMB8/NR4A1/NAIP/PLAUR/GPX1/JAK2/LGALS9/GRN/CTSH/SYK/NLRP3/SORL1/BID/TNF/RHOA/BIRC3/MBP/FYN/APAF1/PSME2/SERPINB1/TIMP2/PSME1/PICALM/RPS6KA3/PAK2/STAT3/CFLAR/CSTB/ROCK1/CAST/CARD8/TANK/DDX3X/PRNP/HERPUD1/BIRC2	57
GO:0002698	negative regulation of immune effector process	25/896	110/18722	5.36650754973628e-11	1.66138129560586e-09	FGL2/HLA-B/PTPRC/HLA-A/SPI1/HLA-E/BST2/ARRB2/IRAK3/PTPN6/LILRB1/CX3CR1/LGALS9/GRN/HLA-F/NCKAP1L/TGFB1/CCR2/TNF/CD300A/BCL6/AHR/CD84/HMOX1/TMBIM6	25
GO:0002704	negative regulation of leukocyte mediated immunity	19/896	63/18722	5.72585594653169e-11	1.76214063774623e-09	HLA-B/PTPRC/HLA-A/SPI1/HLA-E/BST2/ARRB2/PTPN6/LILRB1/CX3CR1/LGALS9/HLA-F/NCKAP1L/CCR2/CD300A/BCL6/AHR/CD84/HMOX1	19
GO:0043434	response to peptide hormone	53/896	414/18722	6.28004572270881e-11	1.92132457669462e-09	IL1B/CYBB/CYBA/TIMP1/TNFSF10/EGR1/LYN/BTG2/GNAI2/PTGS2/STAT1/SOCS3/NR4A1/AGTRAP/RETN/NR4A2/PTPRE/JAK2/IQGAP1/VPS13C/UCP2/PRKCB/TLR2/STAT2/SORL1/CSK/STAT6/FYN/HHEX/ZFP36L1/OSBPL8/JUND/PDK4/BTG1/RAB8B/RHOQ/PAK1/GRB2/STAT3/CFLAR/ROCK1/PTEN/ZNF106/RAP1B/PIP4K2A/IRS2/PHIP/RAB10/PTPN2/SP1/MAX/NFKB1/CREB1	53
GO:0002283	neutrophil activation involved in immune response	11/896	18/18722	6.63961124020792e-11	2.01945134855681e-09	TYROBP/FCER1G/ITGB2/STXBP2/SPI1/SYK/PRAM1/LILRA2/MYD88/ITGAM/PTAFR	11
GO:0051090	regulation of DNA-binding transcription factor activity	55/896	440/18722	6.84857981726397e-11	2.07089904823197e-09	S100A9/S100A8/IL1B/TMSB4X/S100A12/PYCARD/NFKBIA/CARD16/SPI1/CLEC7A/FLNA/KLF4/CD36/TNFAIP3/HCK/ARRB2/CYP1B1/IRAK3/MTDH/JAK2/CX3CR1/LGALS9/PRKCB/TLR2/TRIM22/SYK/NLRP3/TNF/MYD88/TLR4/SLCO3A1/NFAM1/BTK/HSPA1A/HCLS1/TRIM38/TRIB1/SP100/CHP1/MTPN/SGK1/STAT3/CFLAR/PTEN/CYLD/RB1/CARD8/COMMD6/ZBTB7A/HMOX1/PPP3CA/PRNP/EP300/KDM5A/CIB1	55
GO:0045824	negative regulation of innate immune response	20/896	71/18722	7.15320473820517e-11	2.15050970193093e-09	HLA-B/HLA-A/SAMHD1/IFI16/ISG15/TNFAIP3/HLA-E/ARRB2/IRAK3/USP15/LILRB1/LGALS9/GRN/HLA-F/STAT2/OAS1/PARP14/ADAR/PTPN2/NMI	20
GO:0045639	positive regulation of myeloid cell differentiation	24/896	103/18722	7.45198294767882e-11	2.22453361994135e-09	TYROBP/FOS/EVI2B/CD74/ISG15/HLA-DRB1/STAT1/CCR1/CD4/NCKAP1L/TGFB1/NOTCH2/TNF/INPP5D/JUN/ZFP36L1/HSPA1A/HCLS1/TRIB1/STAT3/RB1/KLF10/HIF1A/CREB1	24
GO:0051258	protein polymerization	43/896	296/18722	7.48497180330199e-11	2.22453361994135e-09	AIF1/TMSB4X/COTL1/PYCARD/CORO1A/GMFG/HCK/ACTR2/WAS/TMSB10/JAK2/VASP/MYADM/NCKAP1L/ARPC1B/ARPC3/CAPG/RHOA/GAS7/PSTPIP1/PREX1/PTK2B/MSRB1/HSPA1A/HCLS1/ACTR3/CDC42EP3/ARPC4/NIN/CAPZA1/PAK1/MTPN/CAPZA2/GRB2/TWF2/DIAPH1/PFN1/DBNL/ARPC5/FLII/SSH2/BRK1/ZNF207	43
GO:0030888	regulation of B cell proliferation	19/896	64/18722	7.78191871677635e-11	2.29964541170192e-09	MNDA/TYROBP/PTPRC/CD74/TNFSF13B/LYN/MEF2C/NCKAP1L/BST1/TLR4/CD300A/INPP5D/BCL6/BTK/AHR/PKN1/CDKN1A/ATM/IRS2	19
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	31/896	168/18722	8.31426515386507e-11	2.44307870425154e-09	IL1B/HLA-B/PTPRC/HLA-A/HLA-DRA/TNFSF13B/TNFRSF1B/B2M/NFKBIZ/CLEC7A/SLC11A1/HLA-DRB1/TNFAIP3/HLA-E/WAS/MEF2C/PTPN6/LILRB1/HLA-F/CD4/NCKAP1L/TGFB1/NLRP3/CCR2/TNF/STAT6/BCL6/BTK/AHR/PKN1/STX7	31
GO:0071677	positive regulation of mononuclear cell migration	19/896	65/18722	1.05080678165142e-10	3.05680934869853e-09	AIF1/PYCARD/CCL3/SPI1/ITGA4/CX3CR1/CCR1/LGALS9/CCR2/TNF/TNFRSF14/RHOA/SPN/CCL4/PTK2B/DOCK8/ADAM10/ADAM17/WNK1	19
GO:0001959	regulation of cytokine-mediated signaling pathway	29/896	150/18722	1.05204551704871e-10	3.05680934869853e-09	PTPRC/LAPTM5/SAMHD1/CD74/PYCARD/CARD16/ISG15/CASP1/TNFAIP3/IRAK3/PTPN6/IL1RN/SYK/STAT2/CXCR4/OAS1/PARP9/CD300LF/IRF7/SH2B3/HSPA1A/PARP14/CYLD/HIF1A/CARD8/ADAR/PTPN2/HIPK1/ADAM17	29
GO:0002758	innate immune response-activating signal transduction	12/896	23/18722	1.11452864355711e-10	3.2203685973003e-09	FCN1/TYROBP/CLEC7A/LYN/HCK/SYK/LILRA2/FYN/PAK1/PAK2/CREBBP/EP300	12
GO:0051092	positive regulation of NF-kappaB transcription factor activity	29/896	152/18722	1.46827124113739e-10	4.21904901942295e-09	S100A9/S100A8/IL1B/S100A12/PYCARD/CARD16/CLEC7A/CD36/IRAK3/MTDH/CX3CR1/LGALS9/PRKCB/TLR2/TRIM22/NLRP3/TNF/MYD88/TLR4/SLCO3A1/BTK/HSPA1A/TRIM38/MTPN/STAT3/CFLAR/ZBTB7A/EP300/CIB1	29
GO:2000116	regulation of cysteine-type endopeptidase activity	37/896	235/18722	1.56322480103288e-10	4.46721548910551e-09	S100A9/S100A8/LAPTM5/PYCARD/CD44/CARD16/TNFSF10/PSMB9/CLEC7A/KLF4/IFI16/CASP1/PTGS2/ARRB2/NR4A1/NAIP/PLAUR/GPX1/JAK2/LGALS9/CTSH/SYK/NLRP3/BID/TNF/RHOA/BIRC3/FYN/APAF1/RPS6KA3/PAK2/CFLAR/CAST/CARD8/DDX3X/HERPUD1/BIRC2	37
GO:0006801	superoxide metabolic process	20/896	74/18722	1.63106302097651e-10	4.63560588639281e-09	TYROBP/CYBB/CYBA/ITGB2/NCF1/SOD2/NCF2/CLEC7A/CD36/GNAI2/TGFB1/SYK/BST1/ITGAM/NCF4/HVCN1/GCH1/PREX1/CYB5R4/GNAI3	20
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	14/896	34/18722	1.70036921245029e-10	4.80631536627934e-09	CTSS/FCER1G/HLA-DRA/CD74/PYCARD/HLA-DPA1/B2M/HLA-DPB1/IFI30/HLA-DRB1/HLA-DQB1/HLA-DMA/HLA-DMB/HLA-DQA1	14
GO:0008360	regulation of cell shape	29/896	154/18722	2.03659672452537e-10	5.72558895365214e-09	LST1/ITGB2/CORO1A/CCL3/MSN/FGR/PLEKHO1/RHOB/HCK/RAC2/FMNL1/CSF1R/PLXNC1/RHOA/FGD2/FYN/FGD4/PTK2B/RHOG/SH3KBP1/ARAP1/CDC42EP3/RHOQ/DIAPH1/PLXNB2/MYH9/PHIP/CDC42SE1/ARHGDIA	29
GO:0050792	regulation of viral process	30/896	164/18722	2.09187155570042e-10	5.84936772107414e-09	FCN1/ZFP36/APOBEC3A/CD74/IFITM3/LGALS1/IFI16/ISG15/PABPC1/HLA-DRB1/STAT1/BST2/CXCL8/MX1/IFITM2/LGALS9/TRIM22/CD4/PLSCR1/CXCR4/OAS1/OAS2/TNF/TRIM38/FAM111A/DDX5/IFIH1/ADAR/DYNLT1/DDX3X	30
GO:1901214	regulation of neuron death	44/896	319/18722	2.49932213030262e-10	6.95132320839783e-09	TYROBP/FOS/ITGB2/SOD2/CORO1A/TNFRSF1B/CCL3/MCL1/C5AR1/LRRK2/EGR1/BTG2/ARRB2/NAIP/MEF2C/CEBPB/NR4A2/JAK2/CX3CR1/PPT1/GRN/HLA-F/CTSZ/SORL1/TNF/ITGAM/RHOA/TLR4/FYN/JUN/PTK2B/REL/CAPN2/G6PD/CHP1/PICALM/CDC42/STAT3/HIF1A/MAP3K11/HMOX1/NQO2/PRNP/CREB1	44
GO:2000403	positive regulation of lymphocyte migration	14/896	35/18722	2.70966231711367e-10	7.4962519741001e-09	AIF1/PYCARD/CCL3/ITGA4/CCR2/TNFRSF14/RHOA/SPN/CCL4/PTK2B/DOCK8/ADAM10/ADAM17/WNK1	14
GO:2001233	regulation of apoptotic signaling pathway	47/896	356/18722	2.74230884149269e-10	7.53681504383707e-09	S100A9/S100A8/IL1B/PTPRC/CD74/PYCARD/SOD2/CD44/MCL1/TNFSF10/LRRK2/GNAI2/PTGS2/TNFAIP3/ARRB2/PLAUR/NR4A2/GPX1/CX3CR1/CTSH/BID/TNF/FYN/HSPA1A/STK4/SP100/SKIL/PAK2/CFLAR/IVNS1ABP/PTEN/CYLD/RB1/HIF1A/ZNF385A/ATF3/HMOX1/PHIP/PTPN2/LTBR/GNAI3/TMBIM6/DDX3X/GRINA/HERPUD1/PEA15/RB1CC1	47
GO:2000379	positive regulation of reactive oxygen species metabolic process	20/896	76/18722	2.75617730481995e-10	7.53681504383707e-09	TYROBP/CYBA/ITGB2/TSPO/SOD2/CLEC7A/CD36/GNAI2/TGFB1/SYK/ITGAM/TLR4/RAB27A/HVCN1/PTK2B/GRB2/CDKN1A/TGFBR2/NQO2/GNAI3	20
GO:0071496	cellular response to external stimulus	44/896	320/18722	2.7677978722801e-10	7.53681504383707e-09	AIF1/IL1B/CYBA/FOS/PTPRC/NAMPT/IRF1/LRRK2/LYN/IFI16/CASP1/PTGS2/CD68/ASGR1/ITGA4/NR4A2/UCP2/MAP3K1/TLR8/MYD88/UPP1/TLR4/CNN2/JUN/GLUL/RALB/PDK4/GABARAP/PRKAG2/MTPN/CDKN1A/TNFRSF1A/MAP3K2/KLF10/MAPK1/ATF3/HMOX1/LTBR/MAX/PLEC/ARHGDIA/USF2/LAMP2/NFKB1	44
GO:0022604	regulation of cell morphogenesis	43/896	309/18722	3.01556799635109e-10	8.12640888550363e-09	LST1/ITGB2/CORO1A/CD44/CCL3/MSN/FLNA/FGR/PLEKHO1/RHOB/GBP1/HCK/ACTR2/RAC2/FMNL1/MYADM/CSF1R/CXCR4/PLXNC1/RHOA/FGD2/FYN/FGD4/PREX1/PTK2B/RHOG/SH3KBP1/ARAP1/CDC42EP3/CFL1/RHOQ/CDC42/DIAPH1/ITSN2/LIMS1/PLXNB2/DBNL/CORO1C/MYH9/PHIP/CDC42SE1/ARHGDIA/CIB1	43
GO:0070372	regulation of ERK1 and ERK2 cascade	43/896	309/18722	3.01556799635109e-10	8.12640888550363e-09	IL1B/DUSP1/PTPRC/CCL3L3/CD74/PYCARD/CD44/CCL3/DUSP6/C5AR1/LYN/KLF4/CD36/HLA-DRB1/GNAI2/GBP1/ARRB2/SCIMP/GLIPR2/PTPN6/CCR1/LGALS9/CD4/TGFB1/SYK/NOTCH2/CSF1R/CSK/TNF/GPBAR1/TLR4/CCL4/PTK2B/RAP1A/RRAS/SIRPA/CFLAR/PTEN/RAP1B/ATF3/NQO2/PTPN2/CIB1	43
GO:0097191	extrinsic apoptotic signaling pathway	35/896	219/18722	3.22696712958844e-10	8.65126600051004e-09	IL1B/PTPRC/PYCARD/TNFRSF1B/MCL1/BCL2A1/SPI1/TNFSF10/TNFAIP3/GPX1/JAK2/TGFB1/BID/TNF/IL6R/FYN/HSPA1A/STK4/SP100/SKIL/GABARAP/PAK2/TNFRSF1A/CFLAR/PTEN/CYLD/ATF3/HMOX1/PHIP/LTBR/HIPK1/DDX3X/PEA15/RB1CC1/CIB1	35
GO:0045055	regulated exocytosis	36/896	230/18722	3.27368386370443e-10	8.73150244878294e-09	ITGB2/CORO1A/CCL3/STXBP2/SPI1/LRRK2/PLEK/LYN/FGR/GNAI2/HCK/RAC2/LGALS9/HLA-F/PRKCB/NCKAP1L/SYK/CCR2/LAT2/PRAM1/STX11/ITGAM/RAB27A/ADGRE2/PTAFR/CD300A/BTK/CD84/RAP1A/RAP1B/RAB11FIP1/CTBP2/HMOX1/MYH9/RAB10/BLOC1S6	36
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	13/896	30/18722	3.55807096154481e-10	9.44159544438497e-09	CTSS/FCER1G/HLA-DRA/CD74/HLA-DPA1/B2M/HLA-DPB1/IFI30/HLA-DRB1/HLA-DQB1/HLA-DMA/HLA-DMB/HLA-DQA1	13
GO:0032271	regulation of protein polymerization	36/896	232/18722	4.18790795477085e-10	1.10565021689153e-08	TMSB4X/COTL1/PYCARD/CORO1A/GMFG/HCK/ACTR2/WAS/TMSB10/VASP/MYADM/NCKAP1L/ARPC1B/ARPC3/CAPG/RHOA/PREX1/PTK2B/HSPA1A/HCLS1/ACTR3/CDC42EP3/ARPC4/NIN/CAPZA1/PAK1/MTPN/CAPZA2/GRB2/TWF2/PFN1/DBNL/ARPC5/FLII/SSH2/BRK1	36
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	14/896	36/18722	4.23956942438469e-10	1.11363639273862e-08	CTSS/FCER1G/HLA-DRA/CD74/PYCARD/HLA-DPA1/B2M/HLA-DPB1/IFI30/HLA-DRB1/HLA-DQB1/HLA-DMA/HLA-DMB/HLA-DQA1	14
GO:0006469	negative regulation of protein kinase activity	34/896	212/18722	5.25266643382002e-10	1.37282000614562e-08	IL1B/DUSP1/PTPRC/RGS2/PYCARD/GADD45B/LYN/TNFAIP3/IRAK3/PTPN6/SORL1/SLC8A1/CD300A/HHEX/SH2B3/TRIB1/PKN1/CHP1/PRKAG2/PAK2/CDKN1A/PRKAR1A/GNAQ/STK38/PTEN/HIPK3/RB1/ADAR/CORO1C/DUSP22/PTPN2/MVP/PLEC/NUP62	34
GO:0045089	positive regulation of innate immune response	26/896	131/18722	5.33920173029175e-10	1.38845940996237e-08	FCN1/MNDA/TYROBP/PYCARD/SPI1/CLEC7A/LYN/IFI16/HLA-E/HCK/HLA-F/GBP5/SYK/PLSCR1/TLR8/LILRA2/TLR4/PARP9/FYN/IRF7/IFI35/PAK1/PAK2/NMI/CREBBP/EP300	26
GO:0061515	myeloid cell development	19/896	71/18722	5.62989851551674e-10	1.45395662220917e-08	TYROBP/EVI2B/KLF2/PTPN6/LILRB1/TLR2/NCKAP1L/NOTCH2/FLI1/SH2B3/BCL6/G6PD/PTBP3/ARID4A/ZNF385A/ZBTB7A/PIP4K2A/ABI1/EP300	19
GO:0002688	regulation of leukocyte chemotaxis	25/896	122/18722	5.64697630621521e-10	1.45395662220917e-08	AIF1/DUSP1/CD74/CCL3/SPI1/C5AR1/LYN/GPSM3/CXCL8/RAC2/CX3CR1/CCR1/LGALS9/NCKAP1L/CCR2/BST1/CSF1R/IL6R/RIN3/CCL4/PTK2B/ADAM10/MAPK1/ADAM17/WNK1	25
GO:0030217	T cell differentiation	38/896	257/18722	5.70980008981171e-10	1.46289016094141e-08	FGL2/IL1B/FCER1G/PTPRC/ZFP36L2/HLA-DRA/CD74/IRF1/B2M/SPI1/NFKBIZ/EGR1/HLA-DRB1/LILRB2/MAFB/CD83/LGALS9/CD4/NCKAP1L/SYK/DOCK2/CD86/NLRP3/CCR2/LFNG/TCIRG1/STAT6/RHOA/IL6R/SPN/BCL6/PREX1/ZFP36L1/STAT3/TGFBR2/PTPN2/ADAM17/SP3	38
GO:0031098	stress-activated protein kinase signaling cascade	37/896	247/18722	6.63431860319205e-10	1.69142603211774e-08	IL1B/NCF1/ZFP36/DUSP1/PYCARD/SPI1/LRRK2/GADD45B/CLEC7A/LYN/SCIMP/LGALS9/RASSF2/TNF/MYD88/RHOA/TLR4/MAP3K3/PTK2B/ZFP36L1/TRIB1/TAOK3/CDC42/SIRPA/SDCBP/HIPK3/CYLD/MAPK1/MAP3K11/RNF13/PJA2/DUSP22/LTBR/TAOK1/RB1CC1/NFKB1/NBR1	37
GO:0050729	positive regulation of inflammatory response	27/896	142/18722	6.83110673175798e-10	1.73310176155479e-08	S100A9/S100A8/IL1B/S100A12/NFKBIA/NEAT1/CCL3/LRRK2/NFKBIZ/PTGS2/HLA-E/GPSM3/CEBPB/IL17RA/JAK2/GRN/TLR2/CCR2/LILRA5/TNF/TLR4/BTK/IFI35/ALOX5AP/TNFRSF1A/NMI/NINJ1	27
GO:0062207	regulation of pattern recognition receptor signaling pathway	23/896	105/18722	6.88961700636415e-10	1.7394610703932e-08	CYBA/IRF1/LYN/CD36/TNFAIP3/ARRB2/IRAK3/USP15/TLR2/LILRA2/TLR4/CD300LF/BIRC3/IRF7/CD300A/TLR1/HSPA1A/IFI35/SEC14L1/PJA2/DDX3X/NINJ1/BIRC2	23
GO:0060337	type I interferon signaling pathway	16/896	50/18722	7.05517428078009e-10	1.77265514175542e-08	SAMHD1/IFITM3/ISG15/STAT1/PTPN6/IFITM2/STAT2/OAS1/OAS2/MYD88/IRF7/JAK1/SP100/ADAR/PTPN2/IFNAR1	16
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	32/896	193/18722	7.16200245566265e-10	1.7908449409568e-08	NCF1/PTPRC/CD74/CD44/CLEC7A/LYN/CD36/ARRB2/FCGR1A/PECAM1/JAK2/IQGAP1/CD4/TGFB1/SYK/HBEGF/CSF1R/LILRA5/TNF/TNFRSF14/IL6R/PARP9/FYN/PTK2B/HCLS1/PARP14/ITGA5/PAK2/TNFRSF1A/ABI1/ADAM17/PRNP	32
GO:0001909	leukocyte mediated cytotoxicity	25/896	124/18722	8.10217533938304e-10	2.01623990144168e-08	TYROBP/HLA-B/PTPRC/HLA-A/HLA-DRA/CORO1A/STXBP2/B2M/SPI1/LYST/HLA-DRB1/HLA-E/ARRB2/PTPN6/LILRB1/CX3CR1/LGALS9/HLA-F/CTSH/NCKAP1L/TREM1/MYD88/ITGAM/RAB27A/STX7	25
GO:0051051	negative regulation of transport	55/896	470/18722	8.23755113901583e-10	2.04016683209625e-08	IL1B/RGS2/CD74/CORO1A/TNFRSF1B/SPI1/LRRK2/CD36/GNAI2/PTGS2/BST2/LILRB2/LILRB1/LGALS9/HLA-F/UCP2/PRKCB/TLR2/NCKAP1L/OAZ1/PLSCR1/CCR2/KCNE3/CSK/TNF/RIN3/CD33/CD300LF/MCTP1/CD300A/CNN2/PTK2B/MIDN/CALM2/ANKRD13D/SP100/CD84/CHP1/RAP1A/PICALM/ATG3/TNFRSF1A/SIRPA/SDCBP/PTEN/RAP1B/RAB11FIP1/HMOX1/IRS2/PPP3CA/CAB39/TMBIM6/WNK1/PEA15/NFKB1	55
GO:0046777	protein autophosphorylation	35/896	227/18722	8.73433372461604e-10	2.15295117069801e-08	PTPRC/LRRK2/LYN/FGR/HCK/IRAK3/STK17B/JAK2/IQGAP1/SYK/CSF1R/CSK/RASSF2/FYN/BTK/MAP3K3/PTK2B/MAPKAPK3/STK10/CALM2/STK4/CHP1/PAK1/TAOK3/PAK2/PRKACA/MAP3K11/ATM/CLK1/TAOK1/RAP2B/MVP/DDX3X/WNK1/SMG1	35
GO:0002700	regulation of production of molecular mediator of immune response	29/896	164/18722	9.59134996495064e-10	2.34840356440911e-08	IL1B/PTPRC/HLA-A/LAPTM5/CD74/TNFRSF1B/B2M/CLEC7A/CD36/HLA-E/BST2/SCIMP/IRAK3/LILRB1/HLA-F/TGFB1/CD86/NLRP3/CCR2/TNF/TNFRSF14/STAT6/TLR4/BCL6/BTK/PKN1/HMOX1/TMBIM6/DDX21	29
GO:0002763	positive regulation of myeloid leukocyte differentiation	17/896	58/18722	9.66272568320611e-10	2.34840356440911e-08	TYROBP/FOS/EVI2B/CD74/HLA-DRB1/CCR1/CD4/TGFB1/NOTCH2/TNF/JUN/ZFP36L1/HCLS1/TRIB1/RB1/KLF10/CREB1	17
GO:0034340	response to type I interferon	17/896	58/18722	9.66272568320611e-10	2.34840356440911e-08	SAMHD1/IFITM3/ISG15/STAT1/PTPN6/MX1/IFITM2/STAT2/OAS1/OAS2/MYD88/IRF7/JAK1/SP100/ADAR/PTPN2/IFNAR1	17
GO:0007229	integrin-mediated signaling pathway	23/896	107/18722	1.02309878509073e-09	2.47494734011947e-08	ITGB2/TIMP1/PLEK/FLNA/FGR/ISG15/HCK/ITGA4/ZYX/ITGAL/FERMT3/SYK/PRAM1/BST1/ITGAM/ITGAX/PTK2B/TLN1/ITGA5/CDC42/LIMS1/ADAM10/MYH9	23
GO:0070664	negative regulation of leukocyte proliferation	21/896	90/18722	1.10946029849058e-09	2.67143657983773e-08	MNDA/LST1/TYROBP/LYN/HLA-DRB1/TNFAIP3/LILRB2/CEBPB/PTPN6/LILRB1/LGALS9/CD86/TNFRSF14/CD300A/SPN/INPP5D/BTK/PKN1/PRKAR1A/ATM/PRNP	21
GO:0060333	interferon-gamma-mediated signaling pathway	12/896	27/18722	1.19949764891578e-09	2.8749250101433e-08	IRF1/STAT1/HCK/IFNGR2/JAK2/PARP9/JAK1/PARP14/SP100/IFNGR1/PTPN2/NMI	12
GO:0002220	innate immune response activating cell surface receptor signaling pathway	11/896	22/18722	1.23318197896623e-09	2.94210067550613e-08	FCN1/TYROBP/CLEC7A/LYN/SYK/LILRA2/FYN/PAK1/PAK2/CREBBP/EP300	11
GO:0097193	intrinsic apoptotic signaling pathway	40/896	288/18722	1.33644720449498e-09	3.17390954820932e-08	S100A9/S100A8/CD74/PYCARD/SOD2/CRIP1/CD44/TNFRSF1B/MCL1/BCL2A1/LRRK2/IFI16/PTGS2/CYP1B1/PLAUR/CEBPB/GPX1/JAK2/BID/TNF/APAF1/HSPA1A/PPP1R15A/SKIL/CDKN1A/DDX5/TNFRSF1A/IVNS1ABP/CYLD/HIF1A/ZNF385A/ATM/HMOX1/PTPN2/HIPK1/TMBIM6/DDX3X/EP300/GRINA/HERPUD1	40
GO:0002218	activation of innate immune response	16/896	52/18722	1.35690055471694e-09	3.19332116972073e-08	FCN1/MNDA/TYROBP/PYCARD/CLEC7A/LYN/IFI16/HCK/SYK/LILRA2/TLR4/FYN/PAK1/PAK2/CREBBP/EP300	16
GO:0071357	cellular response to type I interferon	16/896	52/18722	1.35690055471694e-09	3.19332116972073e-08	SAMHD1/IFITM3/ISG15/STAT1/PTPN6/IFITM2/STAT2/OAS1/OAS2/MYD88/IRF7/JAK1/SP100/ADAR/PTPN2/IFNAR1	16
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	33/896	209/18722	1.42201887640627e-09	3.33149557485991e-08	S100A9/S100A8/LAPTM5/PYCARD/CD44/CARD16/TNFSF10/CLEC7A/KLF4/CASP1/PTGS2/ARRB2/NR4A1/NAIP/PLAUR/GPX1/JAK2/LGALS9/CTSH/SYK/NLRP3/BID/TNF/RHOA/BIRC3/APAF1/RPS6KA3/PAK2/CFLAR/CARD8/DDX3X/HERPUD1/BIRC2	33
GO:0050671	positive regulation of lymphocyte proliferation	26/896	137/18722	1.47309299532622e-09	3.43567563618461e-08	AIF1/IL1B/PTPRC/HLA-A/CD74/PYCARD/CORO1A/TNFSF13B/HLA-DPA1/HLA-DPB1/HLA-E/LILRB2/HLA-DMB/MEF2C/LGALS9/NCKAP1L/SYK/CD86/CCR2/BST1/MYD88/TLR4/BCL6/CDKN1A/TGFBR2/IRS2	26
GO:0050672	negative regulation of lymphocyte proliferation	20/896	83/18722	1.50475215058295e-09	3.49384639963478e-08	MNDA/LST1/TYROBP/LYN/HLA-DRB1/LILRB2/CEBPB/PTPN6/LILRB1/LGALS9/CD86/TNFRSF14/CD300A/SPN/INPP5D/BTK/PKN1/PRKAR1A/ATM/PRNP	20
GO:0034121	regulation of toll-like receptor signaling pathway	19/896	75/18722	1.55387422247522e-09	3.59186659159717e-08	CYBA/IRF1/LYN/CD36/TNFAIP3/ARRB2/IRAK3/TLR2/LILRA2/CD300LF/BIRC3/IRF7/CD300A/TLR1/IFI35/PJA2/DDX3X/NINJ1/BIRC2	19
GO:0032946	positive regulation of mononuclear cell proliferation	26/896	138/18722	1.73397144659653e-09	3.99043605918077e-08	AIF1/IL1B/PTPRC/HLA-A/CD74/PYCARD/CORO1A/TNFSF13B/HLA-DPA1/HLA-DPB1/HLA-E/LILRB2/HLA-DMB/MEF2C/LGALS9/NCKAP1L/SYK/CD86/CCR2/BST1/MYD88/TLR4/BCL6/CDKN1A/TGFBR2/IRS2	26
GO:0032945	negative regulation of mononuclear cell proliferation	20/896	84/18722	1.88727448775261e-09	4.32410335277591e-08	MNDA/LST1/TYROBP/LYN/HLA-DRB1/LILRB2/CEBPB/PTPN6/LILRB1/LGALS9/CD86/TNFRSF14/CD300A/SPN/INPP5D/BTK/PKN1/PRKAR1A/ATM/PRNP	20
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	12/896	28/18722	2.00789234921568e-09	4.58028425801349e-08	FCER1G/HLA-B/HLA-C/HLA-A/B2M/IFI30/HLA-E/HLA-F/CLEC4A/TAP1/TAPBP/LNPEP	12
GO:1903306	negative regulation of regulated secretory pathway	11/896	23/18722	2.26143366735922e-09	5.13612074407656e-08	SPI1/GNAI2/LGALS9/HLA-F/NCKAP1L/CCR2/CD300A/CD84/RAP1A/RAP1B/HMOX1	11
GO:0002690	positive regulation of leukocyte chemotaxis	21/896	94/18722	2.59129098975639e-09	5.8596975816187e-08	AIF1/CD74/CCL3/SPI1/C5AR1/GPSM3/CXCL8/RAC2/CX3CR1/CCR1/LGALS9/NCKAP1L/CCR2/CSF1R/IL6R/CCL4/PTK2B/ADAM10/MAPK1/ADAM17/WNK1	21
GO:0042129	regulation of T cell proliferation	29/896	171/18722	2.62339226851098e-09	5.90185501302935e-08	AIF1/IL1B/PTPRC/HLA-A/PYCARD/CORO1A/TNFSF13B/TNFRSF1B/HLA-DPA1/IRF1/HLA-DPB1/HLA-DRB1/HLA-E/LILRB2/HLA-DMB/RAC2/CEBPB/PTPN6/LILRB1/LGALS9/NCKAP1L/SYK/CD86/CCR2/TNFRSF14/SPN/PRKAR1A/TGFBR2/PRNP	29
GO:1901222	regulation of NIK/NF-kappaB signaling	23/896	112/18722	2.63262903869027e-09	5.90185501302935e-08	IL1B/CD14/TMSB4X/LAPTM5/NFKBIA/SPI1/LGALS9/TLR2/CD86/NLRP3/C20orf27/RASSF2/TNF/RHOA/TLR4/IFI35/LITAF/CYLD/LIMS1/NMI/DDX3X/EP300/BIRC2	23
GO:0032535	regulation of cellular component size	47/896	382/18722	2.86376832101007e-09	6.39247168994566e-08	TMSB4X/COTL1/PYCARD/CORO1A/GMFG/MSN/PLEK/HCK/ACTR2/WAS/TMSB10/VASP/MYADM/TMEM123/NCKAP1L/ARPC1B/ARPC3/CAPG/RHOA/RIN3/ARHGAP4/PREX1/PTK2B/LAMTOR4/DPYSL2/HCLS1/PPP1R15A/ACTR3/CDC42EP3/ARPC4/CAPZA1/SHTN1/PICALM/PAK1/MTPN/CAPZA2/GRB2/TWF2/PTEN/PFN1/DBNL/ARPC5/FLII/SSH2/BRK1/RB1CC1/CREB1	47
GO:0032615	interleukin-12 production	17/896	62/18722	3.01960297989389e-09	6.65464199085937e-08	HLA-B/LAPTM5/IRF1/CLEC7A/CD36/ARRB2/SCIMP/IRAK3/LILRB1/LGALS9/TLR2/SYK/TLR8/LILRA5/TLR4/IRF8/NFKB1	17
GO:0032655	regulation of interleukin-12 production	17/896	62/18722	3.01960297989389e-09	6.65464199085937e-08	HLA-B/LAPTM5/IRF1/CLEC7A/CD36/ARRB2/SCIMP/IRAK3/LILRB1/LGALS9/TLR2/SYK/TLR8/LILRA5/TLR4/IRF8/NFKB1	17
GO:0032757	positive regulation of interleukin-8 production	17/896	62/18722	3.01960297989389e-09	6.65464199085937e-08	FCN1/IL1B/CD14/CD74/PYCARD/CLEC7A/LGALS9/TLR2/SYK/TLR8/LILRA2/TNF/MYD88/TLR4/TLR1/HSPA1A/STAT3	17
GO:0032479	regulation of type I interferon production	21/896	95/18722	3.1787480061853e-09	6.94649931939905e-08	CD14/PYCARD/IRF1/ISG15/STAT1/LILRB1/TLR2/SYK/TLR8/OAS1/OAS2/MYD88/TLR4/IRF7/IRF8/REL/SIRPA/CYLD/IFIH1/NMI/DDX3X	21
GO:0032606	type I interferon production	21/896	95/18722	3.1787480061853e-09	6.94649931939905e-08	CD14/PYCARD/IRF1/ISG15/STAT1/LILRB1/TLR2/SYK/TLR8/OAS1/OAS2/MYD88/TLR4/IRF7/IRF8/REL/SIRPA/CYLD/IFIH1/NMI/DDX3X	21
GO:0009612	response to mechanical stimulus	33/896	216/18722	3.35230113235983e-09	7.29511221313952e-08	IL1B/CYBA/FOS/TXNIP/NFKBIA/IRF1/FOSB/BTG2/CASP1/PTGS2/STAT1/RETN/MAP3K1/SLC8A1/TLR8/CXCR4/MYD88/RHOA/TLR4/FYN/CNN2/JUN/PTK2B/JUND/MTPN/TNFRSF1A/MAP3K2/MBD2/TGFBR2/LTBR/PLEC/ARHGDIA/NFKB1	33
GO:0002396	MHC protein complex assembly	10/896	19/18722	3.73713555925285e-09	8.06507968617181e-08	HLA-DRA/HLA-DPA1/B2M/HLA-DPB1/HLA-DRB1/HLA-DQB1/HLA-DMA/HLA-DMB/HLA-DQA1/TAPBP	10
GO:0002483	antigen processing and presentation of endogenous peptide antigen	10/896	19/18722	3.73713555925285e-09	8.06507968617181e-08	HLA-B/HLA-C/HLA-A/HLA-DRA/B2M/HLA-DRB1/HLA-E/HLA-F/TAP1/TAPBP	10
GO:0038061	NIK/NF-kappaB signaling	26/896	143/18722	3.82358291482324e-09	8.21754328098995e-08	IL1B/CD14/TMSB4X/LAPTM5/NFKBIA/SPI1/LGALS9/TLR2/CD86/NLRP3/C20orf27/RASSF2/TNF/RHOA/TLR4/BIRC3/REL/IFI35/LITAF/CYLD/LIMS1/DICER1/NMI/DDX3X/EP300/BIRC2	26
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	11/896	24/18722	3.99454707232022e-09	8.54964581199073e-08	IRF1/IRAK3/TLR2/TLR8/MYD88/TLR4/CD300LF/IRF7/CD300A/TLR1/BTK	11
GO:0022408	negative regulation of cell-cell adhesion	31/896	196/18722	4.28348287438757e-09	9.13048952036465e-08	FGL2/LAPTM5/CD74/IRF1/SPI1/FXYD5/KLF4/HLA-DRB1/LILRB2/CEBPB/PTPN6/LILRB1/JAK2/LGALS9/IL1RN/MYADM/NCKAP1L/TGFB1/CD86/TNFRSF14/MBP/CD300A/SPN/PAG1/SH2B3/BCL6/TNFAIP8L2/PRKAR1A/PTPN2/PRNP/WNK1	31
GO:0002449	lymphocyte mediated immunity	44/896	350/18722	4.75595305929419e-09	1.0096208923016e-07	IL1B/FCER1G/HLA-B/PTPRC/HLA-A/HLA-DRA/CD74/CORO1A/TNFRSF1B/HLA-DPA1/B2M/HLA-DPB1/LYST/HLA-DRB1/HLA-E/ARRB2/WAS/HLA-DQB1/HLA-DMA/HLA-DMB/PTPN6/LILRB1/LGALS9/HLA-F/CTSH/NCKAP1L/TGFB1/MYO1G/NLRP3/CCR2/TLR8/TNF/MYD88/TCIRG1/STAT6/GAPT/RAB27A/HLA-DQA1/IRF7/INPP5D/BCL6/BTK/AHR/STX7	44
GO:0090322	regulation of superoxide metabolic process	13/896	36/18722	5.25228320647268e-09	1.11045223401888e-07	TYROBP/CYBA/ITGB2/CLEC7A/CD36/GNAI2/TGFB1/SYK/BST1/ITGAM/HVCN1/GCH1/GNAI3	13
GO:0071375	cellular response to peptide hormone stimulus	39/896	290/18722	5.43190704725419e-09	1.14377929363437e-07	IL1B/CYBA/LYN/GNAI2/STAT1/SOCS3/NR4A1/AGTRAP/NR4A2/PTPRE/JAK2/UCP2/PRKCB/SORL1/CSK/STAT6/FYN/ZFP36L1/OSBPL8/PDK4/RAB8B/RHOQ/PAK1/GRB2/STAT3/CFLAR/ROCK1/PTEN/ZNF106/RAP1B/PIP4K2A/IRS2/PHIP/RAB10/PTPN2/SP1/MAX/NFKB1/CREB1	39
GO:0050864	regulation of B cell activation	31/896	198/18722	5.49940578569332e-09	1.15332296336254e-07	MNDA/TYROBP/PTPRC/LAPTM5/ZFP36L2/CD74/TNFSF13B/LYN/TNFAIP3/MEF2C/THEMIS2/PTPN6/NCKAP1L/TGFB1/SYK/BST1/STAT6/TLR4/NFAM1/CD300A/INPP5D/BCL6/BTK/ZFP36L1/SAMSN1/AHR/SH3KBP1/PKN1/CDKN1A/ATM/IRS2	31
GO:0006887	exocytosis	44/896	352/18722	5.66934876760096e-09	1.18418806989127e-07	ITGB2/CORO1A/CCL3/STXBP2/SPI1/LRRK2/PLEK/LYN/TNFAIP2/FGR/GNAI2/HCK/RAC2/CCR1/LGALS9/HLA-F/PRKCB/NCKAP1L/SYK/MYO1G/CCR2/LAT2/PRAM1/STX11/ITGAM/RAB27A/ADGRE2/PTAFR/CD300A/BTK/RALB/RAB8B/CD84/RAP1A/PAK1/SDCBP/RAP1B/RAB11FIP1/TMEM167A/CTBP2/HMOX1/MYH9/RAB10/BLOC1S6	44
GO:0046631	alpha-beta T cell activation	27/896	156/18722	5.8694944144712e-09	1.22108961798659e-07	PTPRC/HLA-A/HLA-DRA/IRF1/NFKBIZ/HLA-DRB1/HLA-E/CD83/LILRB1/LGALS9/CLEC4A/NCKAP1L/SYK/DOCK2/CD86/NLRP3/CCR2/TNFRSF14/TCIRG1/STAT6/RHOA/IL6R/CD300A/SPN/BCL6/STAT3/TGFBR2	27
GO:0032930	positive regulation of superoxide anion generation	10/896	20/18722	7.15351522350926e-09	1.48228815448094e-07	TYROBP/CYBA/ITGB2/CLEC7A/GNAI2/TGFB1/SYK/ITGAM/HVCN1/GNAI3	10
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	24/896	128/18722	8.05301412305566e-09	1.6482195817616e-07	IL1B/NCF1/PYCARD/SPI1/GADD45B/CLEC7A/LYN/SCIMP/RASSF2/TNF/MYD88/TLR4/MAP3K3/PTK2B/TAOK3/CDC42/SDCBP/MAP3K11/RNF13/PJA2/DUSP22/LTBR/TAOK1/RB1CC1	24
GO:0071214	cellular response to abiotic stimulus	42/896	331/18722	8.10074001903171e-09	1.6482195817616e-07	IL1B/CYBA/TSPO/CRIP1/CARD16/NAMPT/IRF1/TIMP1/EGR1/IFI16/RHOB/CASP1/PTGS2/RCSD1/MAP3K1/TLR8/MYD88/TLR4/PTAFR/HVCN1/CNN2/ZFP36L1/CHP1/MTPN/GRB2/CDKN1A/POLK/TNFRSF1A/MAP3K2/PTEN/TANK/NIPBL/ATM/MICU1/LTBR/CAB39/DDX3X/PLEC/ARHGDIA/CREBBP/EP300/NFKB1	42
GO:0104004	cellular response to environmental stimulus	42/896	331/18722	8.10074001903171e-09	1.6482195817616e-07	IL1B/CYBA/TSPO/CRIP1/CARD16/NAMPT/IRF1/TIMP1/EGR1/IFI16/RHOB/CASP1/PTGS2/RCSD1/MAP3K1/TLR8/MYD88/TLR4/PTAFR/HVCN1/CNN2/ZFP36L1/CHP1/MTPN/GRB2/CDKN1A/POLK/TNFRSF1A/MAP3K2/PTEN/TANK/NIPBL/ATM/MICU1/LTBR/CAB39/DDX3X/PLEC/ARHGDIA/CREBBP/EP300/NFKB1	42
GO:0097530	granulocyte migration	26/896	148/18722	8.11275164258737e-09	1.6482195817616e-07	S100A9/S100A8/FCER1G/ITGB2/S100A12/CCL3L3/CD74/CCL3/JAML/C5AR1/CXCL8/RAC2/PECAM1/NCKAP1L/SYK/BST1/CSF1R/TREM1/MYD88/ADGRE2/CD300A/CCL4/PREX1/RHOG/CKLF/MAPK1	26
GO:1903900	regulation of viral life cycle	26/896	148/18722	8.11275164258737e-09	1.6482195817616e-07	FCN1/APOBEC3A/CD74/IFITM3/LGALS1/IFI16/ISG15/PABPC1/HLA-DRB1/BST2/CXCL8/MX1/IFITM2/LGALS9/TRIM22/CD4/PLSCR1/OAS1/OAS2/TNF/TRIM38/FAM111A/DDX5/IFIH1/ADAR/DDX3X	26
GO:0048660	regulation of smooth muscle cell proliferation	29/896	180/18722	8.78836523128649e-09	1.77853259019148e-07	AIF1/CYBA/SOD2/NAMPT/KLF4/GNAI2/PTGS2/TNFAIP3/STAT1/MEF2C/JAK2/TGFB1/HBEGF/TNF/MYD88/RHOA/IL6R/TLR4/PTAFR/JUN/TRIB1/PAK1/CDKN1A/PTEN/HMOX1/TGFBR2/NQO2/GNAI3/GNA13	29
GO:0042554	superoxide anion generation	14/896	44/18722	8.97094275152853e-09	1.80844469963953e-07	TYROBP/CYBB/CYBA/ITGB2/NCF1/NCF2/CLEC7A/GNAI2/TGFB1/SYK/ITGAM/NCF4/HVCN1/GNAI3	14
GO:0002440	production of molecular mediator of immune response	40/896	308/18722	9.49660044752288e-09	1.90702003581338e-07	IL1B/PTPRC/HLA-A/LAPTM5/SAMHD1/HLA-DRA/CD74/TNFRSF1B/HLA-DPA1/B2M/CLEC7A/HLA-DPB1/CD36/HLA-DRB1/HLA-E/BST2/SCIMP/IRAK3/HLA-DQB1/HLA-DMA/HLA-DMB/LILRB1/HLA-F/TGFB1/CD86/NLRP3/CCR2/TREM1/TNF/TNFRSF14/STAT6/TLR4/GAPT/HLA-DQA1/BCL6/BTK/PKN1/HMOX1/TMBIM6/DDX21	40
GO:0002399	MHC class II protein complex assembly	9/896	16/18722	1.06902193887755e-08	2.13026172570963e-07	HLA-DRA/HLA-DPA1/B2M/HLA-DPB1/HLA-DRB1/HLA-DQB1/HLA-DMA/HLA-DMB/HLA-DQA1	9
GO:0002503	peptide antigen assembly with MHC class II protein complex	9/896	16/18722	1.06902193887755e-08	2.13026172570963e-07	HLA-DRA/HLA-DPA1/B2M/HLA-DPB1/HLA-DRB1/HLA-DQB1/HLA-DMA/HLA-DMB/HLA-DQA1	9
GO:0070482	response to oxygen levels	43/896	347/18722	1.09714885165024e-08	2.17796609825683e-07	CYBB/CYBA/SOD2/CARD16/NAMPT/EGR1/CASP1/PTGS2/AGTRAP/NR4A2/UCP2/TLR2/BACH1/SLC8A1/CXCR4/RHOA/APAF1/PTK2B/ZFP36L1/EIF4EBP1/MALAT1/CYB5R4/CAPN2/PAK1/CDKN1A/ATP6V0D1/BNIP3L/ATP6V1A/CFLAR/PTEN/HIF1A/PGK1/GNB1/BNIP2/HMOX1/TGFBR2/MDM4/TMBIM6/ADAM17/CREBBP/EP300/CREB1/BIRC2	43
GO:0043301	negative regulation of leukocyte degranulation	8/896	12/18722	1.11297921334633e-08	2.19265336689935e-07	SPI1/LGALS9/HLA-F/NCKAP1L/CCR2/CD300A/CD84/HMOX1	8
GO:1902563	regulation of neutrophil activation	8/896	12/18722	1.11297921334633e-08	2.19265336689935e-07	ITGB2/SPI1/GRN/SYK/PRAM1/ITGAM/PTAFR/CD300A	8
GO:0019883	antigen processing and presentation of endogenous antigen	11/896	26/18722	1.13190633636556e-08	2.22152636054236e-07	HLA-B/HLA-C/HLA-A/HLA-DRA/CD74/B2M/HLA-DRB1/HLA-E/HLA-F/TAP1/TAPBP	11
GO:0032677	regulation of interleukin-8 production	21/896	102/18722	1.2280098328132e-08	2.40108238363212e-07	FCN1/IL1B/CD14/TMSB4X/PTPRC/CD74/PYCARD/CLEC7A/KLF4/LGALS9/TLR2/SYK/TLR8/LILRA2/TNF/MYD88/TLR4/CD33/TLR1/HSPA1A/STAT3	21
GO:0051403	stress-activated MAPK cascade	34/896	239/18722	1.25083653286368e-08	2.43655460952209e-07	IL1B/NCF1/ZFP36/DUSP1/PYCARD/SPI1/LRRK2/GADD45B/CLEC7A/SCIMP/LGALS9/RASSF2/TNF/MYD88/TLR4/MAP3K3/PTK2B/ZFP36L1/TRIB1/TAOK3/CDC42/SIRPA/SDCBP/HIPK3/CYLD/MAPK1/MAP3K11/PJA2/DUSP22/LTBR/TAOK1/RB1CC1/NFKB1/NBR1	34
GO:0002821	positive regulation of adaptive immune response	22/896	112/18722	1.38219048402437e-08	2.68237787589954e-07	IL1B/HLA-B/PTPRC/HLA-A/HLA-DRA/PYCARD/TNFSF13B/B2M/NFKBIZ/CLEC7A/SLC11A1/HLA-DRB1/HLA-E/HLA-F/CD4/TGFB1/NLRP3/CCR2/TNF/STAT6/BTK/STX7	22
GO:0048659	smooth muscle cell proliferation	29/896	184/18722	1.46233973725381e-08	2.82257667179126e-07	AIF1/CYBA/SOD2/NAMPT/KLF4/GNAI2/PTGS2/TNFAIP3/STAT1/MEF2C/JAK2/TGFB1/HBEGF/TNF/MYD88/RHOA/IL6R/TLR4/PTAFR/JUN/TRIB1/PAK1/CDKN1A/PTEN/HMOX1/TGFBR2/NQO2/GNAI3/GNA13	29
GO:0070302	regulation of stress-activated protein kinase signaling cascade	30/896	195/18722	1.46528687057035e-08	2.82257667179126e-07	IL1B/NCF1/DUSP1/PYCARD/SPI1/GADD45B/CLEC7A/LYN/SCIMP/RASSF2/TNF/MYD88/TLR4/MAP3K3/PTK2B/TAOK3/CDC42/SIRPA/SDCBP/HIPK3/CYLD/MAPK1/MAP3K11/RNF13/PJA2/DUSP22/LTBR/TAOK1/RB1CC1/NBR1	30
GO:0032637	interleukin-8 production	21/896	103/18722	1.47396285361428e-08	2.8288121039291e-07	FCN1/IL1B/CD14/TMSB4X/PTPRC/CD74/PYCARD/CLEC7A/KLF4/LGALS9/TLR2/SYK/TLR8/LILRA2/TNF/MYD88/TLR4/CD33/TLR1/HSPA1A/STAT3	21
GO:0030316	osteoclast differentiation	20/896	94/18722	1.50834705582927e-08	2.88415920491472e-07	TYROBP/FOS/JUNB/CCL3/SNX10/LILRB3/MAFB/CEBPB/LILRB1/CCR1/NOTCH2/OSCAR/CSF1R/RASSF2/TNF/TCIRG1/TLR4/INPP5D/KLF10/CREB1	20
GO:0007568	aging	42/896	339/18722	1.63594772803986e-08	3.11669015880413e-07	FOS/TSPO/SOD2/TNFRSF1B/NAMPT/BCL2A1/B2M/TIMP1/SPI1/LRRK2/PTGS2/CD68/RETN/UCP2/APAF1/INPP5D/BCL6/KYNU/JUN/MAP3K3/SERP1/TIMP2/JUND/LITAF/PICALM/GRB2/CDKN1A/BAZ2B/STAT3/PTEN/LIMS1/MAPK1/ATM/YBX1/MBD2/TGFBR2/EEF2/PPP3CA/PRNP/NUP62/MORC3/CREB1	42
GO:0034113	heterotypic cell-cell adhesion	16/896	61/18722	1.77026327630727e-08	3.34805065457241e-07	IL1B/ITGB2/PTPRC/CD44/KLF4/LILRB2/ITGA4/IL1RN/MYADM/TNF/ITGAX/MBP/ITGA5/SIRPA/NINJ1/WNK1	16
GO:2000401	regulation of lymphocyte migration	16/896	61/18722	1.77026327630727e-08	3.34805065457241e-07	AIF1/PYCARD/CCL3/MSN/ITGA4/CCR2/TNFRSF14/RHOA/SPN/CCL4/PTK2B/STK10/DOCK8/ADAM10/ADAM17/WNK1	16
GO:2000117	negative regulation of cysteine-type endopeptidase activity	19/896	86/18722	1.79662260108078e-08	3.38559208268881e-07	CD44/CARD16/KLF4/IFI16/PTGS2/ARRB2/NR4A1/NAIP/PLAUR/GPX1/TNF/BIRC3/RPS6KA3/PAK2/CAST/CARD8/DDX3X/HERPUD1/BIRC2	19
GO:0002532	production of molecular mediator involved in inflammatory response	20/896	95/18722	1.82580632388548e-08	3.42816559224851e-07	NCF1/PYCARD/CLEC7A/LYN/CD36/GPSM3/IL17RA/GRN/GBP5/SYK/TNF/MYD88/ALOX5/TLR4/BTK/ALOX5AP/STAT3/SIRPA/ADCY7/HIF1A	20
GO:0002431	Fc receptor mediated stimulatory signaling pathway	12/896	33/18722	1.8756417013842e-08	3.50906924061123e-07	FCER1G/PTPRC/LYN/FGR/HCK/SYK/MYO1G/PLSCR1/CSK/FYN/RAP1A/PAK1	12
GO:0002286	T cell activation involved in immune response	22/896	114/18722	1.94177683968155e-08	3.61977825920564e-07	FGL2/FCER1G/LCP1/HLA-DRA/CD74/NFKBIZ/SLC11A1/HLA-DRB1/HLA-DMB/LILRB1/LGALS9/ITGAL/NCKAP1L/CD86/NLRP3/APBB1IP/STAT6/IL6R/RAB27A/SPN/BCL6/STAT3	22
GO:0045576	mast cell activation	16/896	62/18722	2.28097735572218e-08	4.23691543825395e-07	S100A12/STXBP2/LYN/FGR/RAC2/LGALS9/SYK/PLSCR1/LAT2/LCP2/CD300LF/ADGRE2/CD300A/BTK/CD84/HMOX1	16
GO:0097028	dendritic cell differentiation	14/896	47/18722	2.33116095384231e-08	4.31472175122201e-07	HLA-B/SPI1/LYN/LILRB2/TMEM176B/CEBPB/LILRB1/LGALS9/NOTCH2/TMEM176A/IRF8/AZI2/TGFBR2/LTBR	14
GO:0001906	cell killing	29/896	188/18722	2.39427634055174e-08	4.41582668340766e-07	LYZ/TYROBP/HLA-B/PTPRC/S100A12/HLA-A/HLA-DRA/CORO1A/STXBP2/B2M/SPI1/CLEC7A/LYST/HLA-DRB1/HLA-E/ARRB2/PTPN6/LILRB1/CX3CR1/LGALS9/HLA-F/CTSH/NCKAP1L/SYK/TREM1/MYD88/ITGAM/RAB27A/STX7	29
GO:0051402	neuron apoptotic process	34/896	246/18722	2.60676889312995e-08	4.79074382090772e-07	TYROBP/SOD2/CORO1A/CCL3/MCL1/C5AR1/BTG2/ARRB2/NAIP/MEF2C/CEBPB/NR4A2/GPX1/JAK2/CX3CR1/PPT1/GRN/CTSZ/BID/TNF/ITGAM/RHOA/FYN/JUN/PTK2B/G6PD/CDC42/RB1/HIF1A/MAP3K11/HMOX1/NQO2/MAX/PRNP	34
GO:1901216	positive regulation of neuron death	20/896	97/18722	2.65326917275861e-08	4.85903273504139e-07	TYROBP/FOS/ITGB2/CCL3/MCL1/EGR1/GRN/CTSZ/TNF/ITGAM/RHOA/TLR4/FYN/JUN/CAPN2/PICALM/CDC42/MAP3K11/NQO2/PRNP	20
GO:1903305	regulation of regulated secretory pathway	24/896	136/18722	2.76744908814268e-08	5.04266098106987e-07	ITGB2/STXBP2/SPI1/LRRK2/LYN/FGR/GNAI2/RAC2/LGALS9/HLA-F/PRKCB/NCKAP1L/SYK/CCR2/PRAM1/ITGAM/RAB27A/ADGRE2/PTAFR/CD300A/CD84/RAP1A/RAP1B/HMOX1	24
GO:0050869	negative regulation of B cell activation	12/896	34/18722	2.77293028376463e-08	5.04266098106987e-07	MNDA/TYROBP/LAPTM5/LYN/TNFAIP3/CD300A/INPP5D/BCL6/BTK/SAMSN1/PKN1/ATM	12
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	21/896	107/18722	2.98666574667616e-08	5.41242109702533e-07	IL1B/HLA-B/PTPRC/HLA-A/HLA-DRA/TNFSF13B/B2M/NFKBIZ/CLEC7A/SLC11A1/HLA-DRB1/HLA-E/HLA-F/CD4/TGFB1/NLRP3/CCR2/TNF/STAT6/BTK/STX7	21
GO:2001234	negative regulation of apoptotic signaling pathway	32/896	224/18722	3.02247575442858e-08	5.45829736068855e-07	IL1B/CD74/SOD2/CD44/MCL1/LRRK2/GNAI2/PTGS2/TNFAIP3/ARRB2/PLAUR/NR4A2/GPX1/CX3CR1/BID/TNF/FYN/HSPA1A/CFLAR/IVNS1ABP/RB1/HIF1A/ZNF385A/HMOX1/PHIP/GNAI3/TMBIM6/DDX3X/GRINA/HERPUD1/PEA15/RB1CC1	32
GO:0032608	interferon-beta production	15/896	56/18722	3.62961569988287e-08	6.50952801899683e-07	PYCARD/IRF1/ISG15/LILRB1/TLR2/TLR8/OAS1/OAS2/TLR4/IRF7/REL/SIRPA/IFIH1/NMI/DDX3X	15
GO:0032648	regulation of interferon-beta production	15/896	56/18722	3.62961569988287e-08	6.50952801899683e-07	PYCARD/IRF1/ISG15/LILRB1/TLR2/TLR8/OAS1/OAS2/TLR4/IRF7/REL/SIRPA/IFIH1/NMI/DDX3X	15
GO:0042100	B cell proliferation	20/896	99/18722	3.81519414664197e-08	6.81884012257213e-07	MNDA/TYROBP/PTPRC/CD74/TNFSF13B/LYN/MEF2C/NCKAP1L/BST1/TLR4/GAPT/CD300A/INPP5D/BCL6/BTK/AHR/PKN1/CDKN1A/ATM/IRS2	20
GO:0007259	receptor signaling pathway via JAK-STAT	27/896	170/18722	3.88078444057782e-08	6.91231502583741e-07	PTPRC/LYN/STAT1/CYP1B1/SOCS3/JAK2/IL10RA/CCR2/STAT2/CSF1R/TNF/STAT6/IL6R/PARP9/FYN/CD300A/SH2B3/PTK2B/JAK1/HCLS1/PARP14/STAT3/TNFRSF1A/PIAS1/PTPN2/NMI/IFNAR1	27
GO:0097696	receptor signaling pathway via STAT	28/896	181/18722	3.91104169881996e-08	6.94243272203503e-07	PTPRC/LYN/STAT1/CYP1B1/SOCS3/JAK2/IL10RA/TGFB1/CCR2/STAT2/CSF1R/TNF/STAT6/IL6R/PARP9/FYN/CD300A/SH2B3/PTK2B/JAK1/HCLS1/PARP14/STAT3/TNFRSF1A/PIAS1/PTPN2/NMI/IFNAR1	28
GO:0062197	cellular response to chemical stress	41/896	337/18722	4.05822592251721e-08	7.17919490578639e-07	AIF1/FOS/NCF1/TSPO/SOD2/KLF2/MCL1/LRRK2/KLF4/CD36/RHOB/PTGS2/TNFAIP3/CYP1B1/NR4A2/GPX1/JAK2/RCSD1/STAT6/ALOX5/TLR4/MGST1/FYN/GCH1/BTK/JUN/ZFP36L1/HSPA1A/SETX/G6PD/KDM6B/SIRPA/SLC25A24/HIF1A/MAPK1/ATM/HMOX1/MICU1/CAB39/DDX3X/PLEC	41
GO:0002223	stimulatory C-type lectin receptor signaling pathway	9/896	18/18722	4.16511857939812e-08	7.26938984276833e-07	TYROBP/CLEC7A/LYN/SYK/FYN/PAK1/PAK2/CREBBP/EP300	9
GO:0002501	peptide antigen assembly with MHC protein complex	9/896	18/18722	4.16511857939812e-08	7.26938984276833e-07	HLA-DRA/HLA-DPA1/B2M/HLA-DPB1/HLA-DRB1/HLA-DQB1/HLA-DMA/HLA-DMB/HLA-DQA1	9
GO:1990840	response to lectin	9/896	18/18722	4.16511857939812e-08	7.26938984276833e-07	TYROBP/CLEC7A/LYN/SYK/FYN/PAK1/PAK2/CREBBP/EP300	9
GO:1990858	cellular response to lectin	9/896	18/18722	4.16511857939812e-08	7.26938984276833e-07	TYROBP/CLEC7A/LYN/SYK/FYN/PAK1/PAK2/CREBBP/EP300	9
GO:2000406	positive regulation of T cell migration	11/896	29/18722	4.44023592148303e-08	7.72363445740243e-07	AIF1/PYCARD/ITGA4/CCR2/TNFRSF14/RHOA/SPN/DOCK8/ADAM10/ADAM17/WNK1	11
GO:2001236	regulation of extrinsic apoptotic signaling pathway	25/896	151/18722	5.323461908605e-08	9.2291084622182e-07	IL1B/PTPRC/PYCARD/MCL1/TNFSF10/TNFAIP3/GPX1/BID/TNF/FYN/HSPA1A/STK4/SP100/SKIL/PAK2/CFLAR/PTEN/CYLD/ATF3/HMOX1/PHIP/LTBR/DDX3X/PEA15/RB1CC1	25
GO:0050921	positive regulation of chemotaxis	24/896	141/18722	5.6851669660466e-08	9.8234396645875e-07	AIF1/TMSB4X/CD74/CCL3/SPI1/C5AR1/GPSM3/CXCL8/RAC2/CX3CR1/CCR1/LGALS9/NCKAP1L/TGFB1/CCR2/CSF1R/CXCR4/IL6R/CCL4/PTK2B/ADAM10/MAPK1/ADAM17/WNK1	24
GO:0002887	negative regulation of myeloid leukocyte mediated immunity	7/896	10/18722	5.94128896181365e-08	1.02320012882095e-06	SPI1/CX3CR1/LGALS9/CCR2/CD300A/CD84/HMOX1	7
GO:0072678	T cell migration	16/896	66/18722	5.96240056765664e-08	1.02344704133275e-06	AIF1/PYCARD/CCL3/MSN/ITGA4/ITGAL/MYO1G/CCR2/TNFRSF14/RHOA/SPN/DOCK8/ADAM10/ADAM17/PLEC/WNK1	16
GO:0034142	toll-like receptor 4 signaling pathway	13/896	43/18722	6.0853930432245e-08	1.04112267163851e-06	CD14/NFKBIA/LYN/TNFAIP3/SCIMP/LY96/PIK3AP1/OAS1/LILRA2/TLR4/IFI35/NMI/NINJ1	13
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	10/896	24/18722	6.37274379125071e-08	1.0831581849116e-06	HLA-B/PTPRC/HLA-A/HLA-E/ARRB2/LILRB1/CX3CR1/LGALS9/HLA-F/NCKAP1L	10
GO:0032928	regulation of superoxide anion generation	10/896	24/18722	6.37274379125071e-08	1.0831581849116e-06	TYROBP/CYBA/ITGB2/CLEC7A/GNAI2/TGFB1/SYK/ITGAM/HVCN1/GNAI3	10
GO:0019058	viral life cycle	39/896	317/18722	6.42844818973298e-08	1.0890670695375e-06	FCN1/APOBEC3A/CD74/IFITM3/LGALS1/IFI16/ISG15/PABPC1/HLA-DRB1/BST2/CXCL8/MX1/IFITM2/LGALS9/TRIM22/CD4/CD86/PLSCR1/CXCR4/SELPLG/OAS1/OAS2/TNF/TNFRSF14/ATG16L2/CTSB/HSPA1A/TRIM38/ITGA5/FAM111A/CDC42/DDX5/CTBP2/IFIH1/ADAR/PCBP2/DYNLT1/DDX3X/CHMP1B	39
GO:0010952	positive regulation of peptidase activity	29/896	197/18722	6.86982010400021e-08	1.16006280392549e-06	S100A9/S100A8/LAPTM5/PYCARD/TNFSF10/CLEC7A/LYN/IFI16/CASP1/JAK2/LGALS9/GRN/CTSH/SYK/NLRP3/BID/TNF/RHOA/MBP/FYN/APAF1/PSME2/PSME1/PICALM/STAT3/CFLAR/CARD8/TANK/DDX3X	29
GO:1990266	neutrophil migration	22/896	122/18722	6.98281362188463e-08	1.17532730250556e-06	S100A9/S100A8/FCER1G/ITGB2/S100A12/CCL3L3/CD74/CCL3/JAML/C5AR1/CXCL8/RAC2/PECAM1/NCKAP1L/SYK/BST1/TREM1/MYD88/CCL4/PREX1/RHOG/CKLF	22
GO:0000302	response to reactive oxygen species	31/896	222/18722	8.42670652178331e-08	1.41378389096113e-06	FOS/TXNIP/NCF1/DUSP1/SOD2/KLF2/LRRK2/KLF4/CD36/RHOB/TNFAIP3/STAT1/CYP1B1/GPX1/UCP2/SLC8A1/STAT6/FYN/GCH1/BTK/JUN/PTK2B/SETX/CAPN2/KDM6B/SIRPA/HIF1A/MAPK1/PPP1R15B/HMOX1/EEF2	31
GO:0045069	regulation of viral genome replication	18/896	85/18722	8.51288793694079e-08	1.42365048746074e-06	APOBEC3A/IFITM3/IFI16/ISG15/PABPC1/BST2/CXCL8/MX1/IFITM2/PLSCR1/OAS1/OAS2/TNF/FAM111A/DDX5/IFIH1/ADAR/DDX3X	18
GO:0046634	regulation of alpha-beta T cell activation	20/896	104/18722	9.05913536273079e-08	1.50532150228635e-06	PTPRC/HLA-A/HLA-DRA/IRF1/NFKBIZ/HLA-DRB1/HLA-E/CD83/LILRB1/LGALS9/NCKAP1L/SYK/CD86/NLRP3/CCR2/TNFRSF14/RHOA/CD300A/BCL6/TGFBR2	20
GO:0048661	positive regulation of smooth muscle cell proliferation	20/896	104/18722	9.05913536273079e-08	1.50532150228635e-06	AIF1/CYBA/NAMPT/GNAI2/PTGS2/STAT1/JAK2/TGFB1/HBEGF/TNF/MYD88/IL6R/TLR4/PTAFR/JUN/PAK1/HMOX1/TGFBR2/NQO2/GNAI3	20
GO:0002705	positive regulation of leukocyte mediated immunity	23/896	134/18722	9.13412533659835e-08	1.51294859476586e-06	TYROBP/IL1B/ITGB2/HLA-B/PTPRC/HLA-A/HLA-DRA/B2M/SPI1/CLEC7A/HLA-DRB1/HLA-E/SCIMP/HLA-F/TGFB1/NLRP3/TNF/STAT6/ITGAM/PTAFR/BTK/DDX21/STX7	23
GO:0043405	regulation of MAP kinase activity	27/896	177/18722	9.17813286079199e-08	1.51541171457077e-06	IL1B/DUSP1/RGS2/S100A12/LRRK2/LYN/IRAK3/PTPN6/IQGAP1/TGFB1/SYK/SORL1/CSK/TNF/TLR4/FGD2/CD300A/SH2B3/PTK2B/AKAP13/TRIB1/PAK1/TAOK3/STK38/HIPK3/MAP3K11/NUP62	27
GO:0036293	response to decreased oxygen levels	39/896	322/18722	9.7884206570296e-08	1.61106252649402e-06	CYBB/CYBA/SOD2/CARD16/NAMPT/EGR1/CASP1/PTGS2/AGTRAP/NR4A2/UCP2/TLR2/BACH1/SLC8A1/CXCR4/RHOA/APAF1/PTK2B/ZFP36L1/EIF4EBP1/MALAT1/CAPN2/PAK1/BNIP3L/CFLAR/PTEN/HIF1A/PGK1/GNB1/BNIP2/HMOX1/TGFBR2/MDM4/TMBIM6/ADAM17/CREBBP/EP300/CREB1/BIRC2	39
GO:0043523	regulation of neuron apoptotic process	30/896	212/18722	1.00744566917103e-07	1.65291007109101e-06	TYROBP/SOD2/CORO1A/CCL3/MCL1/C5AR1/BTG2/ARRB2/NAIP/MEF2C/CEBPB/NR4A2/JAK2/CX3CR1/PPT1/GRN/CTSZ/TNF/ITGAM/RHOA/FYN/JUN/PTK2B/G6PD/CDC42/HIF1A/MAP3K11/HMOX1/NQO2/PRNP	30
GO:0051091	positive regulation of DNA-binding transcription factor activity	34/896	260/18722	1.03114668004634e-07	1.68647606381165e-06	S100A9/S100A8/IL1B/S100A12/PYCARD/CARD16/CLEC7A/CD36/IRAK3/MTDH/JAK2/CX3CR1/LGALS9/PRKCB/TLR2/TRIM22/NLRP3/TNF/MYD88/TLR4/SLCO3A1/NFAM1/BTK/HSPA1A/HCLS1/TRIM38/MTPN/STAT3/CFLAR/PTEN/ZBTB7A/PPP3CA/EP300/CIB1	34
GO:0033002	muscle cell proliferation	33/896	248/18722	1.04665264527219e-07	1.70647034735444e-06	AIF1/CYBA/SOD2/NAMPT/KLF4/GNAI2/PTGS2/TNFAIP3/STAT1/MEF2C/JAK2/TGFB1/HBEGF/TNF/MYD88/RHOA/IL6R/TLR4/PTAFR/JUN/TRIB1/PAK1/CDKN1A/PRKAR1A/STAT3/CFLAR/PTEN/MAPK1/HMOX1/TGFBR2/NQO2/GNAI3/GNA13	33
GO:0071621	granulocyte chemotaxis	22/896	125/18722	1.09464970497384e-07	1.77914784861529e-06	S100A9/S100A8/FCER1G/ITGB2/S100A12/CCL3L3/CD74/CCL3/JAML/C5AR1/CXCL8/RAC2/NCKAP1L/SYK/BST1/CSF1R/TREM1/ADGRE2/CCL4/PREX1/CKLF/MAPK1	22
GO:0051651	maintenance of location in cell	30/896	213/18722	1.12016396855435e-07	1.81494479764834e-06	S100A9/S100A8/SRGN/CYBA/TSPO/TMSB4X/PTPRC/CORO1A/CCL3/LYN/FTL/FTH1/TMSB10/PTPN6/VPS13C/CD4/SORL1/SLC8A1/CCDC88A/PTK2B/FKBP1A/CALM2/SP100/CHCHD10/TWF2/PRKACA/DIAPH1/SUN2/HNRNPU/MORC3	30
GO:0009595	detection of biotic stimulus	12/896	38/18722	1.14663473878406e-07	1.85206437155773e-06	TSPO/HLA-B/HLA-A/CLEC7A/HLA-DRB1/NAIP/LY96/TLR2/NLRP3/TLR4/TLR1/PAK1	12
GO:0010950	positive regulation of endopeptidase activity	27/896	179/18722	1.16289089735905e-07	1.86811504760611e-06	S100A9/S100A8/LAPTM5/PYCARD/TNFSF10/CLEC7A/LYN/IFI16/CASP1/JAK2/LGALS9/CTSH/SYK/NLRP3/BID/TNF/RHOA/MBP/FYN/APAF1/PSME2/PSME1/PICALM/STAT3/CFLAR/CARD8/DDX3X	27
GO:0042742	defense response to bacterium	41/896	350/18722	1.16375557666675e-07	1.86811504760611e-06	LYZ/S100A9/S100A8/CYBA/FCER1G/S100A12/MPEG1/HLA-A/PYCARD/CFP/C5AR1/SLC11A1/LYST/CD36/FGR/ISG15/CASP1/HLA-E/PLAC8/GBP2/NAIP/CEBPB/GRN/TLR2/GBP4/CD4/SYK/NOTCH2/RNASE6/TREM1/OAS1/OAS2/TNF/MYD88/TNFRSF14/IL6R/TLR4/SPN/IRF8/TNFRSF1A/ADAM17	41
GO:0001776	leukocyte homeostasis	18/896	87/18722	1.24021794247629e-07	1.98473031348283e-06	CD74/CORO1A/TNFSF13B/TSC22D3/LYN/TNFAIP3/MEF2C/LGALS9/NCKAP1L/CCR2/TCIRG1/GAPT/DOCK11/SH2B3/PKN1/SKIL/HIF1A/ADAM17	18
GO:0032874	positive regulation of stress-activated MAPK cascade	22/896	126/18722	1.26727621623037e-07	2.02181092043379e-06	IL1B/NCF1/PYCARD/SPI1/GADD45B/CLEC7A/SCIMP/RASSF2/TNF/MYD88/TLR4/MAP3K3/PTK2B/TAOK3/CDC42/SDCBP/MAP3K11/PJA2/DUSP22/LTBR/TAOK1/RB1CC1	22
GO:0090594	inflammatory response to wounding	8/896	15/18722	1.27183376108311e-07	2.02287687810192e-06	TIMP1/GRN/TGFB1/CCR2/ALOX5/TLR4/HIF1A/HMOX1	8
GO:0051235	maintenance of location	39/896	326/18722	1.35975119235729e-07	2.15611766812508e-06	S100A9/S100A8/IL1B/SRGN/CYBA/TSPO/TMSB4X/PTPRC/CORO1A/NFKBIA/CCL3/LYN/FLNA/FTL/CD36/FTH1/TMSB10/PTPN6/VPS13C/CD4/SORL1/SLC8A1/CCDC88A/TNF/PTK2B/FKBP1A/OSBPL8/CALM2/SP100/CHCHD10/TWF2/PRKACA/DIAPH1/YWHAB/SUN2/HNRNPU/PTPN2/NFKB1/MORC3	39
GO:0032872	regulation of stress-activated MAPK cascade	28/896	192/18722	1.40961698039144e-07	2.22839450304434e-06	IL1B/NCF1/DUSP1/PYCARD/SPI1/GADD45B/CLEC7A/SCIMP/RASSF2/TNF/MYD88/TLR4/MAP3K3/PTK2B/TAOK3/CDC42/SIRPA/SDCBP/HIPK3/CYLD/MAPK1/MAP3K11/PJA2/DUSP22/LTBR/TAOK1/RB1CC1/NBR1	28
GO:0051346	negative regulation of hydrolase activity	43/896	379/18722	1.42349334474959e-07	2.24351178364928e-06	RGS2/SERPINA1/CST3/CD44/CARD16/CSTA/TIMP1/LRRK2/KLF4/IFI16/GNAI2/PTGS2/BST2/ARRB2/NR4A1/NAIP/PLAUR/GPX1/NCKAP1L/SORL1/TNF/BIRC3/FKBP1A/PPP1R15A/SERPINB1/TIMP2/CHP1/PICALM/RPS6KA3/PAK2/CSTB/ROCK1/CAST/CARD8/BOD1L1/OXA1L/TMBIM6/DDX3X/PRNP/WNK1/HERPUD1/KDM5A/BIRC2	43
GO:0035456	response to interferon-beta	11/896	32/18722	1.45079779093748e-07	2.27963725397759e-06	MNDA/IFITM3/IRF1/IFI16/XAF1/STAT1/BST2/IFITM2/PLSCR1/OAS1/CAPN2	11
GO:0031532	actin cytoskeleton reorganization	20/896	107/18722	1.48070330931765e-07	2.31961985294008e-06	GMFG/ARHGDIB/PLEK/FLNA/HCK/PARVG/NOTCH2/CSF1R/RHOA/PHACTR1/GPR65/PTK2B/HCLS1/ARAP1/PAK1/GRB2/CDC42/MYH9/PLEC/ARHGDIA	20
GO:0072676	lymphocyte migration	21/896	117/18722	1.49971185149559e-07	2.34234274463321e-06	AIF1/CCL3L3/PYCARD/CCL3/MSN/ITGA4/ITGAL/MYO1G/CCR2/TNFRSF14/RHOA/SPN/CCL4/PTK2B/STK10/CKLF/DOCK8/ADAM10/ADAM17/PLEC/WNK1	21
GO:0043312	neutrophil degranulation	7/896	11/18722	1.56607621951189e-07	2.43867138253932e-06	ITGB2/STXBP2/SPI1/SYK/PRAM1/ITGAM/PTAFR	7
GO:0002260	lymphocyte homeostasis	15/896	62/18722	1.58774893605482e-07	2.4650394675884e-06	CD74/CORO1A/TNFSF13B/TSC22D3/LYN/TNFAIP3/MEF2C/LGALS9/NCKAP1L/TCIRG1/GAPT/DOCK11/PKN1/SKIL/HIF1A	15
GO:0097305	response to alcohol	33/896	253/18722	1.68437595129654e-07	2.60727360794443e-06	S100A8/CYBB/CYBA/FOS/CD14/TSPO/RGS2/SOD2/KLF2/CCL3/FOSB/SPI1/KLF4/ACTR2/TGFB1/NLRP3/RGS19/RHOA/TBXAS1/FYN/PTK2B/EIF4EBP1/AHR/G6PD/CDKN1A/STAT3/PTEN/ADCY7/GNB1/TGFBR2/EEF2/XRN1/BIRC2	33
GO:0070374	positive regulation of ERK1 and ERK2 cascade	30/896	217/18722	1.69916934565278e-07	2.62236788330566e-06	PTPRC/CCL3L3/CD74/PYCARD/CD44/CCL3/C5AR1/CD36/HLA-DRB1/GNAI2/ARRB2/SCIMP/GLIPR2/CCR1/LGALS9/CD4/TGFB1/NOTCH2/CSF1R/TNF/GPBAR1/TLR4/CCL4/PTK2B/RAP1A/CFLAR/PTEN/RAP1B/NQO2/CIB1	30
GO:0046330	positive regulation of JNK cascade	18/896	89/18722	1.78560712327959e-07	2.74761616809975e-06	IL1B/NCF1/PYCARD/GADD45B/RASSF2/TNF/MYD88/TLR4/PTK2B/TAOK3/CDC42/SDCBP/MAP3K11/PJA2/DUSP22/LTBR/TAOK1/RB1CC1	18
GO:0030838	positive regulation of actin filament polymerization	19/896	99/18722	1.95781603445072e-07	2.98747647150214e-06	PYCARD/CORO1A/GMFG/HCK/ACTR2/WAS/VASP/NCKAP1L/ARPC1B/ARPC3/RHOA/PTK2B/ACTR3/CDC42EP3/ARPC4/GRB2/PFN1/ARPC5/BRK1	19
GO:0031341	regulation of cell killing	19/896	99/18722	1.95781603445072e-07	2.98747647150214e-06	TYROBP/HLA-B/PTPRC/HLA-A/HLA-DRA/B2M/SPI1/CLEC7A/HLA-DRB1/HLA-E/ARRB2/LILRB1/CX3CR1/LGALS9/HLA-F/NCKAP1L/SYK/ITGAM/STX7	19
GO:0045646	regulation of erythrocyte differentiation	13/896	47/18722	1.95871847102909e-07	2.98747647150214e-06	ZFP36/B2M/SPI1/LYN/ISG15/STAT1/MAFB/NCKAP1L/INPP5D/ZFP36L1/HSPA1A/STAT3/HIF1A	13
GO:0051924	regulation of calcium ion transport	33/896	255/18722	2.02902430605721e-07	3.08229900351324e-06	CYBA/TSPO/VMP1/CORO1A/CCL3/LYN/GNAI2/PTGS2/LILRB2/ARRB2/PTPN6/LILRB1/CCR1/CD4/SLC8A1/KCNE3/CXCR4/LILRA5/LILRA2/RHOA/CD33/FYN/CCL4/PTK2B/FKBP1A/AHNAK/CALM2/G6PD/CD84/PRKACA/DIAPH1/TMBIM6/PRNP	33
GO:0002456	T cell mediated immunity	20/896	109/18722	2.0327409309845e-07	3.08229900351324e-06	IL1B/HLA-B/PTPRC/HLA-A/HLA-DRA/TNFRSF1B/B2M/HLA-DRB1/HLA-E/WAS/LILRB1/HLA-F/CTSH/NCKAP1L/MYO1G/NLRP3/CCR2/RAB27A/AHR/STX7	20
GO:0045920	negative regulation of exocytosis	11/896	33/18722	2.08241460133701e-07	3.14844137835866e-06	SPI1/GNAI2/LGALS9/HLA-F/NCKAP1L/CCR2/CD300A/CD84/RAP1A/RAP1B/HMOX1	11
GO:0032729	positive regulation of interferon-gamma production	16/896	72/18722	2.19070624525911e-07	3.30256903814278e-06	IL1B/CD14/HLA-A/PYCARD/HLA-DPA1/CLEC7A/HLA-DPB1/SLC11A1/ISG15/LILRB1/LGALS9/CCR2/TLR8/TNF/TLR4/IRF8	16
GO:0046209	nitric oxide metabolic process	17/896	81/18722	2.2253765411828e-07	3.33549953622241e-06	AIF1/IL1B/TSPO/KLF2/CLEC7A/KLF4/CD36/PTGS2/CYP1B1/JAK2/CX3CR1/TLR2/TNF/TLR4/GCH1/PTK2B/SIRPA	17
GO:0071260	cellular response to mechanical stimulus	17/896	81/18722	2.2253765411828e-07	3.33549953622241e-06	IL1B/CYBA/IRF1/CASP1/PTGS2/MAP3K1/TLR8/MYD88/TLR4/CNN2/MTPN/TNFRSF1A/MAP3K2/LTBR/PLEC/ARHGDIA/NFKB1	17
GO:0071901	negative regulation of protein serine/threonine kinase activity	21/896	120/18722	2.34345045112445e-07	3.50238097594777e-06	IL1B/DUSP1/RGS2/PYCARD/LYN/TNFAIP3/IRAK3/PTPN6/SORL1/SLC8A1/CD300A/HHEX/SH2B3/PRKAG2/CDKN1A/PRKAR1A/STK38/PTEN/HIPK3/RB1/NUP62	21
GO:0001666	response to hypoxia	37/896	307/18722	2.35719216203223e-07	3.51282419333227e-06	CYBB/CYBA/SOD2/CARD16/EGR1/CASP1/PTGS2/AGTRAP/NR4A2/UCP2/TLR2/BACH1/SLC8A1/CXCR4/RHOA/APAF1/PTK2B/ZFP36L1/EIF4EBP1/MALAT1/CAPN2/PAK1/BNIP3L/CFLAR/PTEN/HIF1A/PGK1/GNB1/HMOX1/TGFBR2/MDM4/TMBIM6/ADAM17/CREBBP/EP300/CREB1/BIRC2	37
GO:1903038	negative regulation of leukocyte cell-cell adhesion	23/896	141/18722	2.38093811197868e-07	3.53807403440032e-06	FGL2/LAPTM5/CD74/IRF1/KLF4/HLA-DRB1/LILRB2/CEBPB/PTPN6/LILRB1/LGALS9/NCKAP1L/CD86/TNFRSF14/CD300A/SPN/PAG1/BCL6/TNFAIP8L2/PRKAR1A/PTPN2/PRNP/WNK1	23
GO:0045670	regulation of osteoclast differentiation	15/896	64/18722	2.48850012591123e-07	3.68737582759667e-06	TYROBP/FOS/CCL3/LILRB3/MAFB/CEBPB/LILRB1/CCR1/NOTCH2/RASSF2/TNF/TLR4/INPP5D/KLF10/CREB1	15
GO:1902905	positive regulation of supramolecular fiber organization	29/896	209/18722	2.51285037917025e-07	3.71287921081376e-06	PYCARD/CORO1A/GMFG/PLEK/FLNA/HCK/ACTR2/WAS/GPX1/VASP/NCKAP1L/ARPC1B/ARPC3/CCDC88A/RHOA/GPR65/PTK2B/HSPA1A/ACTR3/CDC42EP3/ARPC4/NIN/PAK1/GRB2/CDC42/RB1/PFN1/ARPC5/BRK1	29
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	13/896	48/18722	2.56935136768566e-07	3.77888784383873e-06	PTPRC/PYCARD/TNFSF10/BID/TNF/STK4/SKIL/PAK2/PTEN/CYLD/ATF3/LTBR/PEA15	13
GO:0019079	viral genome replication	22/896	131/18722	2.57205594447012e-07	3.77888784383873e-06	APOBEC3A/IFITM3/IFI16/ISG15/PABPC1/BST2/CXCL8/MX1/IFITM2/PLSCR1/OAS1/OAS2/TNF/ATG16L2/FAM111A/CDC42/DDX5/CTBP2/IFIH1/ADAR/PCBP2/DDX3X	22
GO:0050848	regulation of calcium-mediated signaling	16/896	73/18722	2.6823528399359e-07	3.90983150019374e-06	CCL3/LRRK2/PLEK/CLEC7A/GBP1/CD4/SYK/BST1/TNF/CCL4/PTK2B/CALM2/CHP1/PRNP/TMBIM4/CIB1	16
GO:0001910	regulation of leukocyte mediated cytotoxicity	17/896	82/18722	2.68373360040216e-07	3.90983150019374e-06	TYROBP/HLA-B/PTPRC/HLA-A/HLA-DRA/B2M/SPI1/HLA-DRB1/HLA-E/ARRB2/LILRB1/CX3CR1/LGALS9/HLA-F/NCKAP1L/ITGAM/STX7	17
GO:2001057	reactive nitrogen species metabolic process	17/896	82/18722	2.68373360040216e-07	3.90983150019374e-06	AIF1/IL1B/TSPO/KLF2/CLEC7A/KLF4/CD36/PTGS2/CYP1B1/JAK2/CX3CR1/TLR2/TNF/TLR4/GCH1/PTK2B/SIRPA	17
GO:0002446	neutrophil mediated immunity	11/896	34/18722	2.94573361449205e-07	4.27954204719921e-06	ITGB2/STXBP2/SPI1/SYK/PRAM1/TREM1/MYD88/ITGAM/PTAFR/KMT2E/ADAM17	11
GO:0002720	positive regulation of cytokine production involved in immune response	15/896	65/18722	3.09330541797394e-07	4.4814154537277e-06	IL1B/HLA-A/LAPTM5/CD74/B2M/CLEC7A/CD36/HLA-E/SCIMP/LILRB1/HLA-F/NLRP3/TNFRSF14/TLR4/DDX21	15
GO:0050920	regulation of chemotaxis	30/896	223/18722	3.105766173456e-07	4.48696940781797e-06	AIF1/TMSB4X/DUSP1/CD74/CCL3/SPI1/C5AR1/LYN/GPSM3/CXCL8/RAC2/CX3CR1/CCR1/LGALS9/NCKAP1L/TGFB1/CCR2/BST1/CSF1R/CXCR4/IL6R/RIN3/CCL4/PTK2B/ADAM10/MAPK1/MYCBP2/PTPN2/ADAM17/WNK1	30
GO:0050868	negative regulation of T cell activation	21/896	122/18722	3.12802143920373e-07	4.50660374107995e-06	FGL2/LAPTM5/CD74/IRF1/HLA-DRB1/LILRB2/CEBPB/PTPN6/LILRB1/LGALS9/NCKAP1L/CD86/TNFRSF14/CD300A/SPN/PAG1/BCL6/TNFAIP8L2/PRKAR1A/PTPN2/PRNP	21
GO:0032609	interferon-gamma production	20/896	112/18722	3.22043488261382e-07	4.61418232079186e-06	IL1B/CD14/HLA-A/LAPTM5/PYCARD/HLA-DPA1/CLEC7A/HLA-DPB1/SLC11A1/ISG15/HLA-DRB1/LILRB1/LGALS9/CCR2/TLR8/TNF/TLR4/IRF8/SIRPA/PRNP	20
GO:0032649	regulation of interferon-gamma production	20/896	112/18722	3.22043488261382e-07	4.61418232079186e-06	IL1B/CD14/HLA-A/LAPTM5/PYCARD/HLA-DPA1/CLEC7A/HLA-DPB1/SLC11A1/ISG15/HLA-DRB1/LILRB1/LGALS9/CCR2/TLR8/TNF/TLR4/IRF8/SIRPA/PRNP	20
GO:0001913	T cell mediated cytotoxicity	13/896	49/18722	3.3450301984605e-07	4.76824102153635e-06	HLA-B/PTPRC/HLA-A/HLA-DRA/B2M/HLA-DRB1/HLA-E/LILRB1/HLA-F/CTSH/NCKAP1L/RAB27A/STX7	13
GO:0071902	positive regulation of protein serine/threonine kinase activity	28/896	200/18722	3.34629489109934e-07	4.76824102153635e-06	IL1B/S100A12/LRRK2/DAZAP2/IQGAP1/TGFB1/SYK/CSF1R/CSK/TNF/RHOA/TLR4/FGD2/ACSL1/PTK2B/AKAP13/CALM2/RALB/STK4/PAK1/TAOK3/CCNY/MAP3K11/CAB39/TAOK1/ADAM17/DDX3X/CIB1	28
GO:0060760	positive regulation of response to cytokine stimulus	14/896	57/18722	3.35801130858472e-07	4.77186251801888e-06	LAPTM5/CD74/CASP1/TLR2/CXCR4/TLR4/PARP9/CD300LF/IRF7/HSPA1A/PARP14/HIF1A/IFIH1/ADAM17	14
GO:0031342	negative regulation of cell killing	10/896	28/18722	3.57941755035376e-07	5.04513568547152e-06	HLA-B/PTPRC/HLA-A/HLA-E/ARRB2/LILRB1/CX3CR1/LGALS9/HLA-F/NCKAP1L	10
GO:0038094	Fc-gamma receptor signaling pathway	10/896	28/18722	3.57941755035376e-07	5.04513568547152e-06	FCER1G/PTPRC/LYN/FGR/HCK/SYK/MYO1G/FYN/RAP1A/PAK1	10
GO:0061082	myeloid leukocyte cytokine production	10/896	28/18722	3.57941755035376e-07	5.04513568547152e-06	LAPTM5/CD74/CD36/IRAK3/LILRB1/TGFB1/TLR4/BCL6/HMOX1/DDX21	10
GO:0050852	T cell receptor signaling pathway	21/896	123/18722	3.6047292191779e-07	5.06708018079574e-06	PTPRC/HLA-A/LAPTM5/NFKBIZ/HLA-DPB1/HLA-DRB1/GBP1/HLA-DQB1/THEMIS2/PTPN6/PRAM1/CSK/LCP2/FYN/CD300A/INPP5D/MAPK1/DGKZ/PTPN2/PRNP/WNK1	21
GO:0030593	neutrophil chemotaxis	19/896	103/18722	3.74372218308446e-07	5.24827468307878e-06	S100A9/S100A8/FCER1G/ITGB2/S100A12/CCL3L3/CD74/CCL3/JAML/C5AR1/CXCL8/RAC2/NCKAP1L/SYK/BST1/TREM1/CCL4/PREX1/CKLF	19
GO:0050766	positive regulation of phagocytosis	15/896	66/18722	3.82773640656457e-07	5.3516282393931e-06	IL1B/CYBA/FCER1G/PTPRC/PYCARD/CLEC7A/SLC11A1/CD36/NCKAP1L/DOCK2/TNF/CD300LF/RAB27A/RAP1A/SIRPA	15
GO:0010921	regulation of phosphatase activity	17/896	84/18722	3.86685282656515e-07	5.39182347210867e-06	PTPRC/PLEK/GNAI2/MEF2C/JAK2/NCKAP1L/TNF/CD33/CD300A/FKBP1A/PPP1R15A/CALM2/CHP1/ROCK1/BOD1L1/PPP1R15B/PPP1R12A	17
GO:0033003	regulation of mast cell activation	12/896	42/18722	3.92291114730502e-07	5.45536387089128e-06	STXBP2/LYN/FGR/RAC2/LGALS9/SYK/PLSCR1/CD300LF/ADGRE2/CD300A/CD84/HMOX1	12
GO:0019722	calcium-mediated signaling	28/896	202/18722	4.11950877051226e-07	5.71348403078247e-06	PTPRC/CCL3/LRRK2/PLEK/CLEC7A/GBP1/CXCL8/CX3CR1/CCR1/CD4/SYK/CCR2/LAT2/BST1/SLC8A1/CXCR4/TNF/MCTP1/CCL4/BTK/PTK2B/CALM2/CHP1/PRKACA/PPP3CA/PRNP/TMBIM4/CIB1	28
GO:0032481	positive regulation of type I interferon production	14/896	58/18722	4.23320540339332e-07	5.84002687083519e-06	CD14/IRF1/ISG15/STAT1/TLR2/SYK/TLR8/OAS1/OAS2/MYD88/TLR4/IRF7/IFIH1/DDX3X	14
GO:0043666	regulation of phosphoprotein phosphatase activity	14/896	58/18722	4.23320540339332e-07	5.84002687083519e-06	PTPRC/GNAI2/JAK2/NCKAP1L/TNF/CD33/CD300A/FKBP1A/PPP1R15A/CALM2/ROCK1/BOD1L1/PPP1R15B/PPP1R12A	14
GO:0038093	Fc receptor signaling pathway	13/896	50/18722	4.32370441310881e-07	5.94909699803675e-06	FCER1G/PTPRC/LYN/FGR/HCK/MAP3K1/SYK/MYO1G/FCGR1B/FYN/BTK/RAP1A/PAK1	13
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	8/896	17/18722	4.40944201329094e-07	6.04901497025118e-06	HLA-B/HLA-C/HLA-A/B2M/HLA-E/HLA-F/TAP1/TAPBP	8
GO:0002706	regulation of lymphocyte mediated immunity	25/896	168/18722	4.41958409670342e-07	6.04901497025118e-06	IL1B/HLA-B/PTPRC/HLA-A/HLA-DRA/TNFRSF1B/B2M/HLA-DRB1/HLA-E/ARRB2/WAS/PTPN6/LILRB1/LGALS9/HLA-F/NCKAP1L/TGFB1/NLRP3/CCR2/TNF/STAT6/BCL6/BTK/AHR/STX7	25
GO:0042542	response to hydrogen peroxide	23/896	146/18722	4.52813106115059e-07	6.18131486851554e-06	TXNIP/DUSP1/SOD2/KLF2/LRRK2/KLF4/RHOB/TNFAIP3/STAT1/CYP1B1/GPX1/SLC8A1/STAT6/FYN/JUN/PTK2B/SETX/CAPN2/KDM6B/SIRPA/PPP1R15B/HMOX1/EEF2	23
GO:0002709	regulation of T cell mediated immunity	17/896	85/18722	4.62074383478289e-07	6.29122740437326e-06	IL1B/HLA-B/PTPRC/HLA-A/HLA-DRA/TNFRSF1B/B2M/HLA-DRB1/HLA-E/WAS/LILRB1/HLA-F/NCKAP1L/NLRP3/CCR2/AHR/STX7	17
GO:0046635	positive regulation of alpha-beta T cell activation	15/896	67/18722	4.71587892440288e-07	6.40399119734187e-06	PTPRC/HLA-A/HLA-DRA/NFKBIZ/HLA-DRB1/HLA-E/CD83/LGALS9/NCKAP1L/SYK/CD86/NLRP3/CCR2/RHOA/TGFBR2	15
GO:0006809	nitric oxide biosynthetic process	16/896	76/18722	4.81573043914414e-07	6.52255573280955e-06	AIF1/IL1B/TSPO/KLF2/CLEC7A/KLF4/CD36/PTGS2/CYP1B1/JAK2/CX3CR1/TNF/TLR4/GCH1/PTK2B/SIRPA	16
GO:0050851	antigen receptor-mediated signaling pathway	31/896	240/18722	4.92558265971659e-07	6.65401439303532e-06	MNDA/PTPRC/HLA-A/LAPTM5/NFKBIZ/HLA-DPB1/LYN/HLA-DRB1/GBP1/HLA-DQB1/MEF2C/THEMIS2/PTPN6/PRKCB/NCKAP1L/SYK/LAT2/PRAM1/CSK/LCP2/NFAM1/FYN/CD300A/INPP5D/BTK/CMTM3/MAPK1/DGKZ/PTPN2/PRNP/WNK1	31
GO:0010506	regulation of autophagy	37/896	317/18722	5.25566123615074e-07	7.07322347785692e-06	TSPO/PYCARD/NAMPT/MCL1/LRRK2/IFI16/CASP1/MTDH/PSAP/VPS13C/IL10RA/TRIM22/BID/SPTLC2/TRIM38/RALB/CAPNS1/ATP6V1B2/C9orf72/PRKACA/ATP6V0D1/BNIP3L/ATP6V1A/STAT3/ROCK1/ATP6V0B/HIF1A/ATM/HMOX1/PIP4K2A/CALCOCO2/CTSA/GNAI3/WAC/EP300/DRAM2/SMG1	37
GO:0045766	positive regulation of angiogenesis	26/896	181/18722	5.2766981530638e-07	7.07322347785692e-06	IL1B/CYBB/C5AR1/KLF4/RHOB/CYP1B1/MTDH/CXCL8/CX3CR1/GRN/CTSH/PRKCB/CXCR4/ITGAX/PTK2B/JAK1/BTG1/ITGA5/STAT3/RRAS/HIF1A/HMOX1/TGFBR2/HIPK1/SP1/NINJ1	26
GO:1904018	positive regulation of vasculature development	26/896	181/18722	5.2766981530638e-07	7.07322347785692e-06	IL1B/CYBB/C5AR1/KLF4/RHOB/CYP1B1/MTDH/CXCL8/CX3CR1/GRN/CTSH/PRKCB/CXCR4/ITGAX/PTK2B/JAK1/BTG1/ITGA5/STAT3/RRAS/HIF1A/HMOX1/TGFBR2/HIPK1/SP1/NINJ1	26
GO:0050765	negative regulation of phagocytosis	9/896	23/18722	5.63521806404338e-07	7.5343879565783e-06	TLR2/PLSCR1/CSK/CD300LF/CD300A/CNN2/ATG3/SIRPA/PTEN	9
GO:0030224	monocyte differentiation	11/896	36/18722	5.66476272160103e-07	7.55446946539665e-06	CD74/IFI16/HLA-DRB1/CD4/CSF1R/IRF7/INPP5D/JUN/ZFP36L1/MYH9/SP3	11
GO:0045862	positive regulation of proteolysis	41/896	372/18722	5.99863522251715e-07	7.97925877041219e-06	S100A9/S100A8/IL1B/LAPTM5/PYCARD/TNFRSF1B/TNFSF10/LRRK2/CLEC7A/LYN/IFI16/CASP1/JAK2/LGALS9/GRN/CTSH/SYK/NLRP3/BID/TNF/RHOA/MBP/FYN/APAF1/PTK2B/HSPA1A/PSME2/AGTPBP1/TRIB1/PSME1/GABARAP/PICALM/STAT3/CFLAR/PTEN/CARD8/TANK/PIAS1/MYH9/DDX3X/HERPUD1	41
GO:0010038	response to metal ion	41/896	373/18722	6.43723527878337e-07	8.5408318073858e-06	S100A8/CYBB/FOS/TXNIP/NCF1/CD14/TSPO/DUSP1/JUNB/SOD2/CRIP1/B2M/FOSB/LRRK2/PTGS2/MEF2C/IQGAP1/PLSCR1/TCIRG1/HVCN1/AQP9/RASGRP2/JUN/PTK2B/FBP1/CALM2/MEF2A/JUND/G6PD/ALOX5AP/PTEN/ADCY7/SLC25A24/UBE2D3/HIF1A/MAPK1/HMOX1/PPP3CA/PRNP/WNK1/CREB1	41
GO:0032273	positive regulation of protein polymerization	22/896	138/18722	6.50328600188355e-07	8.6065115765385e-06	PYCARD/CORO1A/GMFG/HCK/ACTR2/WAS/VASP/NCKAP1L/ARPC1B/ARPC3/RHOA/PTK2B/HSPA1A/ACTR3/CDC42EP3/ARPC4/NIN/PAK1/GRB2/PFN1/ARPC5/BRK1	22
GO:0009620	response to fungus	14/896	60/18722	6.62122852953424e-07	8.74035776195624e-06	S100A9/S100A8/S100A12/COTL1/SPI1/CLEC7A/SCIMP/CLEC4E/USP15/CX3CR1/SYK/MYD88/TLR4/BTK	14
GO:0071559	response to transforming growth factor beta	32/896	256/18722	6.78854628410976e-07	8.93853904396326e-06	FOS/ZFP36L2/ZEB2/SPI1/ARRB2/USP15/MEF2C/CX3CR1/ZYX/TGFB1/C20orf27/FYN/APAF1/JUN/ZFP36L1/HSPA1A/FKBP1A/SKIL/STAT3/CFLAR/ROCK1/SDCBP/LIMS1/ZBTB7A/TGFBR2/DUSP22/ADAM17/NR3C1/CREBBP/EP300/FAM89B/CREB1	32
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	16/896	78/18722	6.99074124660303e-07	9.1815265716117e-06	CD44/CARD16/KLF4/PTGS2/ARRB2/NR4A1/NAIP/PLAUR/GPX1/TNF/BIRC3/RPS6KA3/PAK2/DDX3X/HERPUD1/BIRC2	16
GO:1901224	positive regulation of NIK/NF-kappaB signaling	15/896	69/18722	7.06904198551189e-07	9.26097918555349e-06	IL1B/CD14/LAPTM5/LGALS9/TLR2/CD86/C20orf27/TNF/RHOA/TLR4/IFI35/LIMS1/NMI/DDX3X/EP300	15
GO:1901342	regulation of vasculature development	39/896	348/18722	7.39527819742201e-07	9.6640306293447e-06	IL1B/CYBB/KLF2/C5AR1/KLF4/RHOB/TNFAIP3/STAT1/CYP1B1/MTDH/CXCL8/CX3CR1/GRN/CTSH/PRKCB/CCR2/CXCR4/TNF/ALOX5/ITGAX/HHEX/PTK2B/GLUL/JAK1/SP100/BTG1/ITGA5/STAT3/RRAS/ROCK1/HIF1A/PGK1/ADAM10/HMOX1/TGFBR2/HIPK1/SP1/RNH1/NINJ1	39
GO:0070486	leukocyte aggregation	7/896	13/18722	7.48259968757932e-07	9.72925024377502e-06	S100A9/S100A8/IL1B/CD44/MSN/RAC2/STK10	7
GO:2001198	regulation of dendritic cell differentiation	7/896	13/18722	7.48259968757932e-07	9.72925024377502e-06	HLA-B/LILRB2/TMEM176B/CEBPB/LILRB1/LGALS9/TMEM176A	7
GO:0043304	regulation of mast cell degranulation	10/896	30/18722	7.50901296802189e-07	9.73924599667876e-06	STXBP2/LYN/FGR/RAC2/LGALS9/SYK/ADGRE2/CD300A/CD84/HMOX1	10
GO:0030889	negative regulation of B cell proliferation	8/896	18/18722	7.60378613757183e-07	9.83763475161967e-06	MNDA/TYROBP/LYN/CD300A/INPP5D/BTK/PKN1/ATM	8
GO:0045730	respiratory burst	11/896	37/18722	7.71443205149471e-07	9.9560201240258e-06	CYBB/CYBA/NCF1/CD52/NCF2/CLEC7A/SLC11A1/HCK/RAC2/GRN/NCF4	11
GO:0006979	response to oxidative stress	46/896	446/18722	8.36931208831774e-07	1.07744535077576e-05	AIF1/FOS/TXNIP/NCF1/DUSP1/SOD2/KLF2/MCL1/LRRK2/KLF4/CD36/RHOB/PTGS2/TNFAIP3/STAT1/CYP1B1/NR4A2/GPX1/JAK2/UCP2/SLC8A1/STAT6/ALOX5/TLR4/MGST1/MCTP1/FYN/GCH1/BTK/JUN/PTK2B/HSPA1A/SETX/CAPN2/G6PD/BTG1/KDM6B/SIRPA/SLC25A24/HIF1A/MAPK1/PPP1R15B/HMOX1/EEF2/SP1/PRNP	46
GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	15/896	70/18722	8.60312709295248e-07	1.10481145704805e-05	PTPRC/HLA-DRA/HLA-DPA1/B2M/HLA-DPB1/HLA-DRB1/HLA-DQB1/HLA-DMA/HLA-DMB/TGFB1/STAT6/GAPT/HLA-DQA1/BCL6/BTK	15
GO:0045619	regulation of lymphocyte differentiation	25/896	174/18722	8.65538535535265e-07	1.10878471017707e-05	FGL2/PTPRC/ZFP36L2/HLA-DRA/CD74/IRF1/NFKBIZ/HLA-DRB1/LILRB2/CD83/PTPN6/LGALS9/NCKAP1L/SYK/CD86/NLRP3/CCR2/RHOA/NFAM1/INPP5D/BCL6/BTK/ZFP36L1/TGFBR2/PTPN2	25
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	18/896	99/18722	9.43111725889319e-07	1.20519019320647e-05	CD74/PYCARD/CRIP1/CD44/TNFRSF1B/MCL1/BCL2A1/IFI16/BID/TNF/SKIL/CDKN1A/TNFRSF1A/ZNF385A/ATM/HMOX1/HIPK1/EP300	18
GO:0045428	regulation of nitric oxide biosynthetic process	14/896	62/18722	1.01525302191401e-06	1.29419876641538e-05	AIF1/IL1B/TSPO/KLF2/CLEC7A/KLF4/CD36/PTGS2/JAK2/CX3CR1/TNF/TLR4/PTK2B/SIRPA	14
GO:0001782	B cell homeostasis	10/896	31/18722	1.06109346454832e-06	1.34603588027214e-05	CD74/TNFSF13B/LYN/TNFAIP3/MEF2C/NCKAP1L/GAPT/DOCK11/PKN1/HIF1A	10
GO:0033006	regulation of mast cell activation involved in immune response	10/896	31/18722	1.06109346454832e-06	1.34603588027214e-05	STXBP2/LYN/FGR/RAC2/LGALS9/SYK/ADGRE2/CD300A/CD84/HMOX1	10
GO:0035304	regulation of protein dephosphorylation	17/896	90/18722	1.07956875837363e-06	1.36614041661831e-05	PTPRC/GNAI2/LILRB2/JAK2/NCKAP1L/TGFB1/TNF/CD33/CD300A/FKBP1A/PPP1R15A/CALM2/ROCK1/YWHAB/BOD1L1/PPP1R15B/PPP1R12A	17
GO:0006968	cellular defense response	13/896	54/18722	1.13033073303517e-06	1.42690537439706e-05	MNDA/TYROBP/NCF1/NCF2/LSP1/C5AR1/LILRB2/CX3CR1/LY96/CCR2/TCIRG1/SPN/PTK2B	13
GO:2000106	regulation of leukocyte apoptotic process	16/896	81/18722	1.19347332922149e-06	1.50296726035859e-05	CD74/TSC22D3/LYN/MEF2C/LILRB1/LGALS9/GIMAP8/IRF7/BCL6/BTK/HCLS1/DOCK8/PTEN/HIF1A/IRS2/ADAM17	16
GO:0071560	cellular response to transforming growth factor beta stimulus	31/896	250/18722	1.20273078834326e-06	1.51096686719162e-05	FOS/ZFP36L2/ZEB2/SPI1/ARRB2/USP15/MEF2C/CX3CR1/ZYX/TGFB1/C20orf27/FYN/APAF1/JUN/ZFP36L1/HSPA1A/FKBP1A/SKIL/STAT3/CFLAR/SDCBP/LIMS1/ZBTB7A/TGFBR2/DUSP22/ADAM17/NR3C1/CREBBP/EP300/FAM89B/CREB1	31
GO:0031343	positive regulation of cell killing	14/896	63/18722	1.24839447291798e-06	1.56455413340878e-05	TYROBP/HLA-B/PTPRC/HLA-A/HLA-DRA/B2M/SPI1/CLEC7A/HLA-DRB1/HLA-E/HLA-F/SYK/ITGAM/STX7	14
GO:0002888	positive regulation of myeloid leukocyte mediated immunity	8/896	19/18722	1.25827300121314e-06	1.57314372098787e-05	TYROBP/ITGB2/SPI1/HLA-E/ITGAM/PTAFR/BTK/DDX21	8
GO:0045765	regulation of angiogenesis	38/896	342/18722	1.26472981791414e-06	1.57742440838644e-05	IL1B/CYBB/KLF2/C5AR1/KLF4/RHOB/TNFAIP3/STAT1/CYP1B1/MTDH/CXCL8/CX3CR1/GRN/CTSH/PRKCB/CCR2/CXCR4/TNF/ALOX5/ITGAX/HHEX/PTK2B/GLUL/JAK1/SP100/BTG1/ITGA5/STAT3/RRAS/ROCK1/HIF1A/PGK1/HMOX1/TGFBR2/HIPK1/SP1/RNH1/NINJ1	38
GO:0042102	positive regulation of T cell proliferation	18/896	101/18722	1.27887606668676e-06	1.59125225426742e-05	AIF1/IL1B/PTPRC/HLA-A/PYCARD/CORO1A/TNFSF13B/HLA-DPA1/HLA-DPB1/HLA-E/LILRB2/HLA-DMB/LGALS9/NCKAP1L/SYK/CD86/CCR2/TGFBR2	18
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	9/896	25/18722	1.29187493554774e-06	1.59977179518662e-05	CARD16/CD36/TNFAIP3/SCIMP/LY86/LY96/LILRA2/TRIB1/CARD8	9
GO:0098581	detection of external biotic stimulus	9/896	25/18722	1.29187493554774e-06	1.59977179518662e-05	HLA-B/HLA-A/CLEC7A/HLA-DRB1/NAIP/LY96/TLR2/TLR4/TLR1	9
GO:0051495	positive regulation of cytoskeleton organization	29/896	226/18722	1.3102628494558e-06	1.61868814252247e-05	PYCARD/CORO1A/GMFG/PLEK/FLNA/HCK/ACTR2/WAS/VASP/NCKAP1L/ARPC1B/ARPC3/CCDC88A/RHOA/GPR65/PTK2B/HSPA1A/HCLS1/ACTR3/CDC42EP3/ARPC4/NIN/PAK1/GRB2/CDC42/PFN1/ARPC5/BRK1/NUP62	29
GO:0017157	regulation of exocytosis	27/896	202/18722	1.3620191912706e-06	1.67864024023658e-05	ITGB2/STXBP2/SPI1/LRRK2/LYN/FGR/GNAI2/RAC2/LGALS9/HLA-F/PRKCB/NCKAP1L/SYK/CCR2/PRAM1/ITGAM/RAB27A/ADGRE2/PTAFR/CD300A/RAB8B/CD84/RAP1A/SDCBP/RAP1B/HMOX1/RAB10	27
GO:0046328	regulation of JNK cascade	21/896	133/18722	1.36576344146251e-06	1.67927556951454e-05	IL1B/NCF1/PYCARD/GADD45B/RASSF2/TNF/MYD88/TLR4/PTK2B/TAOK3/CDC42/SIRPA/SDCBP/HIPK3/CYLD/MAP3K11/PJA2/DUSP22/LTBR/TAOK1/RB1CC1	21
GO:0001914	regulation of T cell mediated cytotoxicity	11/896	39/18722	1.38495948852231e-06	1.69886186316144e-05	HLA-B/PTPRC/HLA-A/HLA-DRA/B2M/HLA-DRB1/HLA-E/LILRB1/HLA-F/NCKAP1L/STX7	11
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	16/896	82/18722	1.41773998841696e-06	1.73366771955005e-05	SPI1/TNFAIP3/GPX1/BID/TNF/STK4/SP100/SKIL/GABARAP/TNFRSF1A/CFLAR/PTEN/ATF3/HMOX1/DDX3X/PEA15	16
GO:0007254	JNK cascade	24/896	167/18722	1.42000086238862e-06	1.73366771955005e-05	IL1B/NCF1/PYCARD/LRRK2/GADD45B/RASSF2/TNF/MYD88/TLR4/PTK2B/TRIB1/TAOK3/CDC42/SIRPA/SDCBP/HIPK3/CYLD/MAP3K11/PJA2/DUSP22/LTBR/TAOK1/RB1CC1/NFKB1	24
GO:0010951	negative regulation of endopeptidase activity	31/896	252/18722	1.42795007301639e-06	1.73929000696914e-05	SERPINA1/CST3/CD44/CARD16/CSTA/TIMP1/KLF4/IFI16/PTGS2/BST2/ARRB2/NR4A1/NAIP/PLAUR/GPX1/SORL1/TNF/BIRC3/SERPINB1/TIMP2/PICALM/RPS6KA3/PAK2/CSTB/ROCK1/CAST/CARD8/DDX3X/PRNP/HERPUD1/BIRC2	31
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	12/896	47/18722	1.48586837934968e-06	1.80560781331721e-05	LAPTM5/PYCARD/CARD16/CASP1/TNFAIP3/SYK/HSPA1A/CYLD/CARD8/PTPN2/HIPK1/ADAM17	12
GO:0032507	maintenance of protein location in cell	14/896	64/18722	1.5282669218095e-06	1.8484921535654e-05	SRGN/TSPO/TMSB4X/TMSB10/VPS13C/CD4/SORL1/CCDC88A/SP100/CHCHD10/TWF2/SUN2/HNRNPU/MORC3	14
GO:0080164	regulation of nitric oxide metabolic process	14/896	64/18722	1.5282669218095e-06	1.8484921535654e-05	AIF1/IL1B/TSPO/KLF2/CLEC7A/KLF4/CD36/PTGS2/JAK2/CX3CR1/TNF/TLR4/PTK2B/SIRPA	14
GO:0043409	negative regulation of MAPK cascade	25/896	180/18722	1.63775784552325e-06	1.97632913098989e-05	IL1B/DUSP1/PTPRC/RGS2/DUSP6/LYN/KLF4/GBP1/IRAK3/PTPN6/RNF149/SORL1/CSK/TLR4/CD300A/SH2B3/TAOK3/SIRPA/STK38/PTEN/HIPK3/CYLD/ATF3/PTPN2/NUP62	25
GO:0045185	maintenance of protein location	17/896	93/18722	1.74121577844469e-06	2.09631094066917e-05	SRGN/TSPO/TMSB4X/NFKBIA/FLNA/TMSB10/VPS13C/CD4/SORL1/CCDC88A/SP100/CHCHD10/TWF2/YWHAB/SUN2/HNRNPU/MORC3	17
GO:0045071	negative regulation of viral genome replication	13/896	56/18722	1.7638711121871e-06	2.11868213729448e-05	APOBEC3A/IFITM3/IFI16/ISG15/BST2/MX1/IFITM2/PLSCR1/OAS1/OAS2/TNF/FAM111A/IFIH1	13
GO:0045429	positive regulation of nitric oxide biosynthetic process	11/896	40/18722	1.8281507310479e-06	2.19083224704612e-05	AIF1/IL1B/KLF2/CLEC7A/KLF4/CD36/PTGS2/JAK2/TNF/TLR4/PTK2B	11
GO:0006470	protein dephosphorylation	33/896	281/18722	1.87275289021119e-06	2.23912362804331e-05	DUSP1/PTPRC/DUSP6/LRRK2/GNAI2/LILRB2/PTPN6/PTPRE/JAK2/PTP4A2/NCKAP1L/TGFB1/DAPP1/TNF/CD33/CD300A/FKBP1A/PTPN18/PPP1R15A/CALM2/CPPED1/ROCK1/YWHAB/PTEN/BOD1L1/PPP1R15B/SSH2/DUSP23/PPP3CA/DUSP22/PTPN2/PPP1R12A/CTDSP1	33
GO:1900017	positive regulation of cytokine production involved in inflammatory response	9/896	26/18722	1.89209442721991e-06	2.25596385336823e-05	CLEC7A/GPSM3/IL17RA/GBP5/TNF/MYD88/TLR4/STAT3/HIF1A	9
GO:0043303	mast cell degranulation	12/896	48/18722	1.89551279354339e-06	2.25596385336823e-05	STXBP2/LYN/FGR/RAC2/LGALS9/SYK/LAT2/ADGRE2/CD300A/BTK/CD84/HMOX1	12
GO:0007163	establishment or maintenance of cell polarity	28/896	218/18722	1.94989137982772e-06	2.31538471837534e-05	MSN/RHOB/ACTB/ACTR2/RAC2/CAP1/NCKAP1L/DOCK2/PARVG/TCIRG1/RHOA/SPN/CCL4/PTK2B/RHOG/ACTR3/CYTH1/SHTN1/PAK1/CDC42/DOCK8/ROCK1/RAP1B/ARPC5/MYH9/RAB10/DYNLT1/FAM89B	28
GO:0098543	detection of other organism	8/896	20/18722	2.00917651819807e-06	2.38034785219776e-05	HLA-B/HLA-A/CLEC7A/HLA-DRB1/NAIP/TLR2/TLR4/TLR1	8
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	6/896	10/18722	2.10290483502945e-06	2.48572910158822e-05	FGL2/HLA-DMB/LILRB1/LGALS9/ITGAL/APBB1IP	6
GO:0051098	regulation of binding	39/896	363/18722	2.11954183317692e-06	2.49971362230231e-05	TMSB4X/NFKBIA/CARD16/B2M/LRRK2/IFIT2/KLF4/IFI16/ACTB/ARRB2/PLAUR/ITGA4/JAK2/TGFB1/CTSZ/SORL1/PARP9/JUN/FKBP1A/CALM2/RALB/STK4/SP100/DTX3L/C9orf72/CDKN1A/CDC42/PRKACA/ROCK1/RB1/CTBP2/ZBTB7A/HMOX1/CCPG1/MBD2/PPP3CA/TMBIM6/TAF10/EP300	39
GO:0061756	leukocyte adhesion to vascular endothelial cell	13/896	57/18722	2.18580087939783e-06	2.57202497143622e-05	ITGB2/KLF4/SELL/ITGA4/CX3CR1/CCR2/SELPLG/TNF/ALOX5/RHOA/PTAFR/SPN/ROCK1	13
GO:0009410	response to xenobiotic stimulus	46/896	462/18722	2.21465737882918e-06	2.60009774882405e-05	IL1B/CYBB/CYBA/FOS/TXNIP/TSPO/APOBEC3A/S100A12/SOD2/LGALS1/DUSP6/B2M/FOSB/LYN/PTGS2/STAT1/CYP1B1/MEF2C/GPX1/NCKAP1L/RNF149/SULT1A1/SLC8A1/CXCR4/RHOA/MGST1/FYN/JUN/ACSL1/PTK2B/FBP1/AHR/TIMP2/RAP1A/CDKN1A/STAT3/PTEN/RB1/RAP1B/HMOX1/TGFBR2/EEF2/PPP1R12A/ADAM17/PRNP/CREB1	46
GO:0010959	regulation of metal ion transport	42/896	406/18722	2.31846502467974e-06	2.71584157508093e-05	CYBA/TSPO/VMP1/CORO1A/CCL3/B2M/LYN/FLNA/FXYD5/GNAI2/PTGS2/LILRB2/ARRB2/PTPN6/LILRB1/CCR1/CD4/SLC8A1/KCNE3/CXCR4/LILRA5/LILRA2/RHOA/CD33/FYN/CCL4/PTK2B/GLRX/FKBP1A/AHNAK/CALM2/G6PD/CD84/CHP1/PRKACA/DIAPH1/PTEN/SLC31A2/CAB39/TMBIM6/PRNP/WNK1	42
GO:1904407	positive regulation of nitric oxide metabolic process	11/896	41/18722	2.39107936418698e-06	2.79460758946887e-05	AIF1/IL1B/KLF2/CLEC7A/KLF4/CD36/PTGS2/JAK2/TNF/TLR4/PTK2B	11
GO:0002279	mast cell activation involved in immune response	12/896	49/18722	2.40178623366145e-06	2.80082739938861e-05	STXBP2/LYN/FGR/RAC2/LGALS9/SYK/LAT2/ADGRE2/CD300A/BTK/CD84/HMOX1	12
GO:0002468	dendritic cell antigen processing and presentation	7/896	15/18722	2.57851912723582e-06	3.00019641627595e-05	FGL2/HLA-DRA/CD74/SLC11A1/HLA-DRB1/CD68/CLEC4A	7
GO:0043525	positive regulation of neuron apoptotic process	13/896	58/18722	2.69496186623696e-06	3.12868229158447e-05	TYROBP/CCL3/MCL1/GRN/CTSZ/TNF/ITGAM/RHOA/JUN/CDC42/MAP3K11/NQO2/PRNP	13
GO:0071248	cellular response to metal ion	26/896	197/18722	2.70306329517812e-06	3.13109848512726e-05	CYBB/FOS/NCF1/TSPO/JUNB/B2M/FOSB/LRRK2/PTGS2/MEF2C/IQGAP1/HVCN1/RASGRP2/JUN/FBP1/MEF2A/JUND/ALOX5AP/ADCY7/SLC25A24/UBE2D3/MAPK1/HMOX1/PRNP/WNK1/CREB1	26
GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	9/896	27/18722	2.7179455662245e-06	3.13437580708062e-05	PTPRC/LYN/FGR/HCK/SYK/MYO1G/FYN/RAP1A/PAK1	9
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	9/896	27/18722	2.7179455662245e-06	3.13437580708062e-05	PTPRC/LYN/FGR/HCK/SYK/MYO1G/FYN/RAP1A/PAK1	9
GO:0010922	positive regulation of phosphatase activity	10/896	34/18722	2.75210122685917e-06	3.15975242403853e-05	PTPRC/PLEK/MEF2C/JAK2/CD33/CD300A/PPP1R15A/CALM2/PPP1R15B/PPP1R12A	10
GO:0098751	bone cell development	10/896	34/18722	2.75210122685917e-06	3.15975242403853e-05	TYROBP/PTPN6/LILRB1/NOTCH2/FLI1/SH2B3/ZNF385A/PIP4K2A/ABI1/EP300	10
GO:0002702	positive regulation of production of molecular mediator of immune response	19/896	117/18722	2.80318996139237e-06	3.21131960114576e-05	IL1B/PTPRC/HLA-A/LAPTM5/CD74/B2M/CLEC7A/CD36/HLA-E/SCIMP/LILRB1/HLA-F/TGFB1/CD86/NLRP3/TNFRSF14/STAT6/TLR4/DDX21	19
GO:0035303	regulation of dephosphorylation	20/896	128/18722	2.86283986890466e-06	3.27244618860948e-05	PTPRC/PLEK/GNAI2/LILRB2/MEF2C/JAK2/NCKAP1L/TGFB1/TNF/CD33/CD300A/FKBP1A/PPP1R15A/CALM2/CHP1/ROCK1/YWHAB/BOD1L1/PPP1R15B/PPP1R12A	20
GO:0002448	mast cell mediated immunity	12/896	50/18722	3.02370701019321e-06	3.44875003509098e-05	STXBP2/LYN/FGR/RAC2/LGALS9/SYK/LAT2/ADGRE2/CD300A/BTK/CD84/HMOX1	12
GO:0032418	lysosome localization	15/896	77/18722	3.07597422559375e-06	3.50068751582343e-05	STXBP2/LYN/FGR/RAC2/LGALS9/SYK/LAT2/ADGRE2/CD300A/BTK/BLOC1S1/CD84/HMOX1/LAMTOR1/MYH9	15
GO:2000404	regulation of T cell migration	11/896	42/18722	3.1003268075425e-06	3.51583110239872e-05	AIF1/PYCARD/ITGA4/CCR2/TNFRSF14/RHOA/SPN/DOCK8/ADAM10/ADAM17/WNK1	11
GO:0032516	positive regulation of phosphoprotein phosphatase activity	8/896	21/18722	3.10956029052761e-06	3.51583110239872e-05	PTPRC/JAK2/CD33/CD300A/PPP1R15A/CALM2/PPP1R15B/PPP1R12A	8
GO:0035455	response to interferon-alpha	8/896	21/18722	3.10956029052761e-06	3.51583110239872e-05	IFITM3/IFIT2/BST2/IFIT3/IFITM2/MX2/ADAR/IFNAR1	8
GO:0010466	negative regulation of peptidase activity	31/896	262/18722	3.26108137461851e-06	3.67915059205875e-05	SERPINA1/CST3/CD44/CARD16/CSTA/TIMP1/KLF4/IFI16/PTGS2/BST2/ARRB2/NR4A1/NAIP/PLAUR/GPX1/SORL1/TNF/BIRC3/SERPINB1/TIMP2/PICALM/RPS6KA3/PAK2/CSTB/ROCK1/CAST/CARD8/DDX3X/PRNP/HERPUD1/BIRC2	31
GO:2001242	regulation of intrinsic apoptotic signaling pathway	23/896	164/18722	3.57805639370337e-06	4.0280240916994e-05	S100A9/S100A8/CD74/PYCARD/SOD2/CD44/MCL1/LRRK2/PTGS2/PLAUR/GPX1/BID/HSPA1A/SKIL/IVNS1ABP/CYLD/HIF1A/ZNF385A/PTPN2/TMBIM6/DDX3X/GRINA/HERPUD1	23
GO:0050728	negative regulation of inflammatory response	24/896	176/18722	3.64864987175756e-06	4.09862375443004e-05	ZFP36/PTPRC/TNFRSF1B/LYN/KLF4/FGR/HLA-DRB1/TNFAIP3/HCK/SOCS3/AOAH/GPX1/GRN/SYK/NLRP3/ALOX5/FYN/TNFAIP8L2/METRNL/TNFRSF1A/SIRPA/RB1/PTPN2/NFKB1	24
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	17/896	98/18722	3.68618195502845e-06	4.13186041984977e-05	CD74/SOD2/CD44/MCL1/LRRK2/PTGS2/PLAUR/GPX1/BID/HSPA1A/IVNS1ABP/HIF1A/ZNF385A/TMBIM6/DDX3X/GRINA/HERPUD1	17
GO:0032868	response to insulin	31/896	264/18722	3.8228235036839e-06	4.2758075360559e-05	IL1B/TNFSF10/EGR1/LYN/GNAI2/STAT1/SOCS3/RETN/PTPRE/VPS13C/UCP2/PRKCB/TLR2/SORL1/ZFP36L1/OSBPL8/PDK4/RAB8B/RHOQ/PAK1/GRB2/CFLAR/PTEN/ZNF106/PIP4K2A/IRS2/PHIP/RAB10/PTPN2/SP1/MAX	31
GO:0046598	positive regulation of viral entry into host cell	6/896	11/18722	4.43846149072337e-06	4.94313452103902e-05	CD74/LGALS1/HLA-DRB1/LGALS9/CD4/TRIM38	6
GO:0075294	positive regulation by symbiont of entry into host	6/896	11/18722	4.43846149072337e-06	4.94313452103902e-05	CD74/LGALS1/HLA-DRB1/LGALS9/CD4/TRIM38	6
GO:0070555	response to interleukin-1	21/896	143/18722	4.49945371549074e-06	5.00035443894601e-05	IL1B/CYBA/CCL3L3/PYCARD/KLF2/CCL3/EGR1/GBP1/IRAK3/CXCL8/GBP2/CEBPB/LGALS9/IL1RN/MYD88/CCL4/SIRPA/HNMT/HIF1A/TANK/NFKB1	21
GO:0045123	cellular extravasation	14/896	70/18722	4.72400693326452e-06	5.23871216629184e-05	JAML/SELL/PECAM1/ITGA4/CX3CR1/ITGAL/CCR2/BST1/SELPLG/TNF/PTAFR/SPN/SIRPA/ROCK1	14
GO:0030865	cortical cytoskeleton organization	13/896	61/18722	4.90906360736256e-06	5.43234889827504e-05	LCP1/PLEK/RHOB/RAC2/FMNL1/NCKAP1L/TNF/RHOA/RHOG/TLN1/RHOQ/ROCK1/PLEC	13
GO:0034109	homotypic cell-cell adhesion	16/896	90/18722	5.09410702623248e-06	5.62514875656797e-05	LGALS1/PLEK/LYN/FLNA/ACTB/PLAUR/PTPN6/JAK2/FERMT3/SYK/SH2B3/JAK1/TLN1/CLIC1/MYH9/RAP2B	16
GO:0045444	fat cell differentiation	28/896	229/18722	5.13042192541859e-06	5.65324670214027e-05	ZFP36/RGS2/ZFP36L2/KLF4/PTGS2/MAFB/PSMB8/PLAC8/NR4A1/RETN/CEBPB/NR4A2/GPX1/TGFB1/TNF/ALOX5/METRNL/ZFP36L1/OSBPL8/STK4/ZNF385A/CTBP2/NIPBL/PIAS1/ZBTB7A/HNRNPU/EP300/CREB1	28
GO:0001916	positive regulation of T cell mediated cytotoxicity	9/896	29/18722	5.32663793677669e-06	5.85704945225699e-05	HLA-B/PTPRC/HLA-A/HLA-DRA/B2M/HLA-DRB1/HLA-E/HLA-F/STX7	9
GO:0002707	negative regulation of lymphocyte mediated immunity	12/896	53/18722	5.82065587808779e-06	6.38675764175836e-05	HLA-B/PTPRC/HLA-A/HLA-E/ARRB2/PTPN6/LILRB1/LGALS9/HLA-F/NCKAP1L/BCL6/AHR	12
GO:0032613	interleukin-10 production	13/896	62/18722	5.94211539533872e-06	6.49263490990686e-05	TYROBP/PYCARD/CLEC7A/ISG15/HLA-DRB1/CD83/LILRB1/LGALS9/TLR2/SYK/LILRA5/TLR4/STAT3	13
GO:0032653	regulation of interleukin-10 production	13/896	62/18722	5.94211539533872e-06	6.49263490990686e-05	TYROBP/PYCARD/CLEC7A/ISG15/HLA-DRB1/CD83/LILRB1/LGALS9/TLR2/SYK/LILRA5/TLR4/STAT3	13
GO:0071347	cellular response to interleukin-1	18/896	113/18722	6.73445111559503e-06	7.34295183484481e-05	IL1B/CCL3L3/PYCARD/KLF2/CCL3/EGR1/GBP1/IRAK3/CXCL8/GBP2/CEBPB/IL1RN/MYD88/CCL4/SIRPA/HIF1A/TANK/NFKB1	18
GO:0048525	negative regulation of viral process	16/896	92/18722	6.84097815305322e-06	7.44349945063384e-05	FCN1/ZFP36/APOBEC3A/IFITM3/IFI16/ISG15/STAT1/BST2/MX1/IFITM2/PLSCR1/OAS1/OAS2/TNF/FAM111A/IFIH1	16
GO:0010934	macrophage cytokine production	7/896	17/18722	7.16200233908773e-06	7.74419421322147e-05	LAPTM5/CD74/CD36/IRAK3/LILRB1/TGFB1/TLR4	7
GO:0010935	regulation of macrophage cytokine production	7/896	17/18722	7.16200233908773e-06	7.74419421322147e-05	LAPTM5/CD74/CD36/IRAK3/LILRB1/TGFB1/TLR4	7
GO:0035855	megakaryocyte development	7/896	17/18722	7.16200233908773e-06	7.74419421322147e-05	PTPN6/FLI1/SH2B3/ZNF385A/PIP4K2A/ABI1/EP300	7
GO:2001056	positive regulation of cysteine-type endopeptidase activity	21/896	148/18722	7.8009114312892e-06	8.41753949255916e-05	S100A9/S100A8/LAPTM5/PYCARD/TNFSF10/CLEC7A/IFI16/CASP1/JAK2/LGALS9/CTSH/SYK/NLRP3/BID/TNF/RHOA/FYN/APAF1/CFLAR/CARD8/DDX3X	21
GO:0007266	Rho protein signal transduction	20/896	137/18722	8.26815292580283e-06	8.88484780311994e-05	ARHGDIB/RHOB/WAS/RHOA/LPAR6/GPR65/BCL6/ARHGAP4/RHOG/AKAP13/CDC42EP3/CFL1/SHTN1/CDC42/ROCK1/ARHGEF3/MYO9B/CDC42SE1/ARHGDIA/GNA13	20
GO:0045471	response to ethanol	20/896	137/18722	8.26815292580283e-06	8.88484780311994e-05	S100A8/CYBB/CD14/RGS2/SOD2/SPI1/ACTR2/NLRP3/RGS19/RHOA/TBXAS1/FYN/PTK2B/EIF4EBP1/G6PD/STAT3/PTEN/ADCY7/EEF2/BIRC2	20
GO:0007599	hemostasis	27/896	222/18722	8.31004260962017e-06	8.91144981703804e-05	FCER1G/SERPINA1/PLEK/LYN/FLNA/CD36/ACTB/WAS/PLAUR/PTPN6/JAK2/FERMT3/SYK/PLSCR1/FLI1/TLR4/ENTPD1/RAB27A/SH2B3/JMJD1C/TLN1/CLIC1/GNAQ/DGKZ/MYH9/RAP2B/BLOC1S6	27
GO:0046633	alpha-beta T cell proliferation	10/896	38/18722	8.33420176261702e-06	8.91896777106401e-05	PTPRC/HLA-A/IRF1/HLA-E/LGALS9/SYK/DOCK2/CCR2/TNFRSF14/TGFBR2	10
GO:0045621	positive regulation of lymphocyte differentiation	17/896	104/18722	8.46005633323411e-06	9.03506221543133e-05	PTPRC/HLA-DRA/CD74/NFKBIZ/HLA-DRB1/LILRB2/CD83/LGALS9/NCKAP1L/SYK/CD86/NLRP3/RHOA/INPP5D/BCL6/BTK/TGFBR2	17
GO:0034599	cellular response to oxidative stress	32/896	288/18722	8.60142265828831e-06	9.16721296019621e-05	AIF1/FOS/NCF1/SOD2/KLF2/MCL1/LRRK2/KLF4/CD36/RHOB/TNFAIP3/CYP1B1/NR4A2/GPX1/JAK2/STAT6/ALOX5/TLR4/MGST1/FYN/GCH1/BTK/JUN/HSPA1A/SETX/G6PD/KDM6B/SIRPA/SLC25A24/HIF1A/MAPK1/HMOX1	32
GO:0002437	inflammatory response to antigenic stimulus	14/896	74/18722	9.32935553211672e-06	9.92269491258468e-05	LYN/FGR/HLA-DRB1/HLA-E/HCK/CD68/GPX1/IL1RN/SYK/NOTCH2/TNF/FYN/BTK/KDM6B	14
GO:0001659	temperature homeostasis	23/896	174/18722	9.77494127310394e-06	0.000103754019513089	IL1B/EGR1/CD36/PTGS2/PLAC8/CEBPB/GPX1/JAK2/UCP2/SYK/CCR2/CXCR4/TNF/STAT6/TLR4/ALDH1A1/ACSL1/STAT3/KDM6B/RB1/DECR1/LNPEP/ADAM17	23
GO:0051100	negative regulation of binding	22/896	162/18722	9.81196795273497e-06	0.000103934919189765	TMSB4X/NFKBIA/CARD16/B2M/LRRK2/IFIT2/IFI16/ACTB/ARRB2/ITGA4/JAK2/CTSZ/SORL1/JUN/RALB/SP100/C9orf72/CDKN1A/ROCK1/HMOX1/PPP3CA/TMBIM6	22
GO:0034504	protein localization to nucleus	32/896	290/18722	9.92254484130769e-06	0.000104679829045926	TXNIP/NFKBIA/LRRK2/FLNA/CD36/NUP214/PTGS2/GBP2/JAK2/TGFB1/SYK/PARP9/FYN/HHEX/RASSF5/GLUL/HCLS1/OSBPL8/SP100/DTX3L/CHP1/CHCHD10/CDKN1A/STAT3/MAPK1/SUN2/ZBTB7A/HNRNPU/NUP50/PPP3CA/NUP62/MORC3	32
GO:0044403	biological process involved in symbiotic interaction	32/896	290/18722	9.92254484130769e-06	0.000104679829045926	FCN1/CD74/IFITM3/LGALS1/CCL3/HLA-DRB1/CXCL8/GPX1/IFITM2/CX3CR1/LGALS9/TRIM22/CD4/CD86/PLSCR1/CXCR4/TREM1/SELPLG/MYD88/TNFRSF14/CCL4/JUN/CTSB/HSPA1A/TRIM38/CFL1/ITGA5/CHD1/RXRA/DYNLT1/SP1/EP300	32
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	12/896	56/18722	1.06730804275214e-05	0.000112369820452507	TYROBP/HLA-B/PTPRC/HLA-A/HLA-DRA/B2M/SPI1/HLA-DRB1/HLA-E/HLA-F/ITGAM/STX7	12
GO:0032728	positive regulation of interferon-beta production	10/896	39/18722	1.073049220196e-05	0.000112746040287664	IRF1/ISG15/TLR2/TLR8/OAS1/OAS2/TLR4/IRF7/IFIH1/DDX3X	10
GO:0048771	tissue remodeling	23/896	175/18722	1.07550604960163e-05	0.000112776350080203	CST3/TIMP1/FLNA/SNX10/TNFAIP3/RAC2/MEF2C/TPP1/TGFB1/SYK/NOTCH2/CCR2/CSF1R/CSK/RASSF2/TCIRG1/INPP5D/PTK2B/PDK4/ROCK1/LIPA/HIF1A/PPP3CA	23
GO:0071887	leukocyte apoptotic process	17/896	106/18722	1.09904372017334e-05	0.000115012603392787	CD74/TSC22D3/LYN/MEF2C/LILRB1/LGALS9/GIMAP8/IRF7/BCL6/BTK/HCLS1/PKN1/DOCK8/PTEN/HIF1A/IRS2/ADAM17	17
GO:0034134	toll-like receptor 2 signaling pathway	7/896	18/18722	1.12357628915708e-05	0.000116874405598119	CYBA/LYN/TNFAIP3/TLR2/PIK3AP1/TLR1/PJA2	7
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	7/896	18/18722	1.12357628915708e-05	0.000116874405598119	HLA-B/HLA-A/HLA-E/ARRB2/LILRB1/LGALS9/HLA-F	7
GO:0071800	podosome assembly	7/896	18/18722	1.12357628915708e-05	0.000116874405598119	LCP1/MSN/HCK/TNF/RHOA/BIN2/DBNL	7
GO:0071241	cellular response to inorganic substance	27/896	226/18722	1.15636799057761e-05	0.000120045307764355	CYBB/FOS/NCF1/TSPO/JUNB/B2M/FOSB/LRRK2/PTGS2/MEF2C/IQGAP1/HVCN1/RASGRP2/JUN/FBP1/MEF2A/JUND/ALOX5AP/CFLAR/ADCY7/SLC25A24/UBE2D3/MAPK1/HMOX1/PRNP/WNK1/CREB1	27
GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	19/896	129/18722	1.21348187065366e-05	0.000125723490224496	S100A9/S100A8/LAPTM5/PYCARD/TNFSF10/CLEC7A/CASP1/JAK2/LGALS9/CTSH/SYK/NLRP3/BID/TNF/RHOA/APAF1/CFLAR/CARD8/DDX3X	19
GO:0022406	membrane docking	15/896	86/18722	1.27078601896087e-05	0.000131398769077842	VMP1/STXBP2/MSN/PLEK/STX11/STX10/RALB/RAB8B/CHP1/ROCK1/CTBP2/RAB10/STX7/STX12/BLOC1S6	15
GO:1990868	response to chemokine	16/896	97/18722	1.37566594493152e-05	0.000141679971873046	DUSP1/CCL3L3/CCL3/CXCL8/CX3CR1/CCR1/CCR2/CXCR4/RHOA/CCL4/SH2B3/PTK2B/DOCK8/HIF1A/WNK1/CIB1	16
GO:1990869	cellular response to chemokine	16/896	97/18722	1.37566594493152e-05	0.000141679971873046	DUSP1/CCL3L3/CCL3/CXCL8/CX3CR1/CCR1/CCR2/CXCR4/RHOA/CCL4/SH2B3/PTK2B/DOCK8/HIF1A/WNK1/CIB1	16
GO:0070527	platelet aggregation	13/896	67/18722	1.45409458238998e-05	0.000149461381877674	PLEK/LYN/FLNA/ACTB/PTPN6/JAK2/FERMT3/SYK/SH2B3/TLN1/CLIC1/MYH9/RAP2B	13
GO:1903320	regulation of protein modification by small protein conjugation or removal	28/896	242/18722	1.46572109935528e-05	0.000150359278851022	TSPO/LAPTM5/LRRK2/EGR1/ISG15/TNFAIP3/ARRB2/BIRC3/FYN/RASSF5/UBE2D1/HSPA1A/FKBP1A/DTX3L/GABARAP/CHP1/SPOPL/IVNS1ABP/PTEN/HIF1A/TANK/PIAS1/MYCBP2/NMI/DDX3X/HERPUD1/TRIP12/BIRC2	28
GO:0033157	regulation of intracellular protein transport	27/896	229/18722	1.47230326836192e-05	0.000150737190920282	IL1B/LCP1/ITGB2/LRRK2/FLNA/CD36/PTGS2/RAC2/JAK2/TGFB1/OAZ1/SORL1/ITGAM/FYN/HCLS1/SP100/CHP1/PAK1/CDC42/PRKACA/BNIP3L/UBE2D3/TOMM7/MAPK1/PRNP/NUP62/CIB1	27
GO:0030225	macrophage differentiation	11/896	49/18722	1.55239632508112e-05	0.000158004173908941	SPI1/HLA-DRB1/TLR2/CD4/TGFB1/CSF1R/HCLS1/TRIB1/CDC42/RB1/PTPN2	11
GO:0052372	modulation by symbiont of entry into host	11/896	49/18722	1.55239632508112e-05	0.000158004173908941	FCN1/CD74/IFITM3/LGALS1/HLA-DRB1/CXCL8/IFITM2/LGALS9/TRIM22/CD4/TRIM38	11
GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	11/896	49/18722	1.55239632508112e-05	0.000158004173908941	TNFAIP3/GPX1/STK4/SP100/SKIL/CFLAR/PTEN/ATF3/HMOX1/DDX3X/PEA15	11
GO:0007596	blood coagulation	26/896	217/18722	1.5863003123495e-05	0.000161139607900971	FCER1G/SERPINA1/PLEK/LYN/FLNA/CD36/ACTB/WAS/PLAUR/PTPN6/JAK2/FERMT3/SYK/PLSCR1/TLR4/ENTPD1/RAB27A/SH2B3/JMJD1C/TLN1/CLIC1/GNAQ/DGKZ/MYH9/RAP2B/BLOC1S6	26
GO:0002716	negative regulation of natural killer cell mediated immunity	7/896	19/18722	1.70559653276127e-05	0.000172583804803334	HLA-B/HLA-A/HLA-E/ARRB2/LILRB1/LGALS9/HLA-F	7
GO:0140131	positive regulation of lymphocyte chemotaxis	7/896	19/18722	1.70559653276127e-05	0.000172583804803334	CCL3/CCR2/CCL4/PTK2B/ADAM10/ADAM17/WNK1	7
GO:0032633	interleukin-4 production	9/896	33/18722	1.72586703163307e-05	0.000173621555735466	FCER1G/HLA-DRB1/HLA-E/CD83/CEBPB/LGALS9/SYK/CD86/NLRP3	9
GO:0032673	regulation of interleukin-4 production	9/896	33/18722	1.72586703163307e-05	0.000173621555735466	FCER1G/HLA-DRB1/HLA-E/CD83/CEBPB/LGALS9/SYK/CD86/NLRP3	9
GO:0050901	leukocyte tethering or rolling	9/896	33/18722	1.72586703163307e-05	0.000173621555735466	SELL/ITGA4/CX3CR1/CCR2/SELPLG/TNF/PTAFR/SPN/ROCK1	9
GO:0032733	positive regulation of interleukin-10 production	10/896	41/18722	1.73453135507835e-05	0.000173820762577312	PYCARD/CLEC7A/ISG15/CD83/LGALS9/TLR2/SYK/LILRA5/TLR4/STAT3	10
GO:0032735	positive regulation of interleukin-12 production	10/896	41/18722	1.73453135507835e-05	0.000173820762577312	LAPTM5/IRF1/CLEC7A/CD36/SCIMP/LGALS9/TLR2/SYK/TLR4/IRF8	10
GO:0019932	second-messenger-mediated signaling	33/896	312/18722	1.75456864722032e-05	0.000175490606426786	PTPRC/RGS2/FPR1/CCL3/LRRK2/PLEK/CLEC7A/CD36/GBP1/CXCL8/CX3CR1/CCR1/CAP1/CD4/SYK/CCR2/LAT2/BST1/SLC8A1/CXCR4/TNF/MCTP1/CCL4/BTK/PTK2B/AHR/CALM2/CHP1/PRKACA/PPP3CA/PRNP/TMBIM4/CIB1	33
GO:0035306	positive regulation of dephosphorylation	12/896	59/18722	1.87488179321912e-05	0.000186805751083001	PTPRC/PLEK/LILRB2/MEF2C/JAK2/TGFB1/CD33/CD300A/PPP1R15A/CALM2/PPP1R15B/PPP1R12A	12
GO:0043407	negative regulation of MAP kinase activity	12/896	59/18722	1.87488179321912e-05	0.000186805751083001	IL1B/DUSP1/RGS2/LYN/IRAK3/PTPN6/SORL1/CD300A/SH2B3/STK38/HIPK3/NUP62	12
GO:0001961	positive regulation of cytokine-mediated signaling pathway	11/896	50/18722	1.9049676549447e-05	0.000188718795683188	LAPTM5/CD74/CASP1/CXCR4/PARP9/CD300LF/IRF7/HSPA1A/PARP14/HIF1A/ADAM17	11
GO:0045058	T cell selection	11/896	50/18722	1.9049676549447e-05	0.000188718795683188	PTPRC/CD74/CD4/SYK/DOCK2/STAT6/RHOA/IL6R/SPN/STAT3/PTPN2	11
GO:0046638	positive regulation of alpha-beta T cell differentiation	11/896	50/18722	1.9049676549447e-05	0.000188718795683188	HLA-DRA/NFKBIZ/HLA-DRB1/CD83/LGALS9/NCKAP1L/SYK/CD86/NLRP3/RHOA/TGFBR2	11
GO:0034114	regulation of heterotypic cell-cell adhesion	8/896	26/18722	1.92796089484244e-05	0.000190633547796113	IL1B/CD44/KLF4/IL1RN/MYADM/TNF/MBP/WNK1	8
GO:0031668	cellular response to extracellular stimulus	28/896	246/18722	1.9870327791729e-05	0.000196101660047026	AIF1/FOS/PTPRC/NAMPT/LRRK2/LYN/IFI16/CD68/ASGR1/ITGA4/NR4A2/UCP2/UPP1/JUN/GLUL/RALB/PDK4/GABARAP/PRKAG2/CDKN1A/KLF10/MAPK1/ATF3/HMOX1/MAX/PLEC/USF2/LAMP2	28
GO:0016064	immunoglobulin mediated immune response	25/896	207/18722	2.00325667335142e-05	0.000197328370418575	FCER1G/PTPRC/HLA-DRA/CD74/HLA-DPA1/B2M/HLA-DPB1/HLA-DRB1/HLA-E/HLA-DQB1/HLA-DMA/HLA-DMB/PTPN6/TGFB1/TLR8/TNF/MYD88/TCIRG1/STAT6/GAPT/HLA-DQA1/IRF7/INPP5D/BCL6/BTK	25
GO:1901215	negative regulation of neuron death	25/896	208/18722	2.17582100780457e-05	0.000213093102995768	SOD2/CORO1A/TNFRSF1B/C5AR1/LRRK2/BTG2/ARRB2/NAIP/MEF2C/CEBPB/NR4A2/JAK2/CX3CR1/PPT1/GRN/HLA-F/SORL1/RHOA/FYN/PTK2B/REL/STAT3/HIF1A/HMOX1/CREB1	25
GO:0030890	positive regulation of B cell proliferation	10/896	42/18722	2.17968719080463e-05	0.000213093102995768	PTPRC/CD74/TNFSF13B/MEF2C/NCKAP1L/BST1/TLR4/BCL6/CDKN1A/IRS2	10
GO:0046596	regulation of viral entry into host cell	10/896	42/18722	2.17968719080463e-05	0.000213093102995768	FCN1/CD74/IFITM3/LGALS1/HLA-DRB1/IFITM2/LGALS9/TRIM22/CD4/TRIM38	10
GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	10/896	42/18722	2.17968719080463e-05	0.000213093102995768	FOS/SPI1/EGR1/KLF4/TGFB1/TNF/JUN/STAT3/HIF1A/NR3C1	10
GO:0046632	alpha-beta T cell differentiation	17/896	112/18722	2.31162524873135e-05	0.000225567784590089	HLA-DRA/IRF1/NFKBIZ/HLA-DRB1/CD83/LGALS9/NCKAP1L/SYK/CD86/NLRP3/STAT6/RHOA/IL6R/SPN/BCL6/STAT3/TGFBR2	17
GO:0050830	defense response to Gram-positive bacterium	16/896	101/18722	2.31962768878971e-05	0.000225924786692795	LYZ/MPEG1/HLA-A/PYCARD/C5AR1/CD36/FGR/HLA-E/GBP2/TLR2/GBP4/RNASE6/TNF/MYD88/TNFRSF14/ADAM17	16
GO:0050817	coagulation	26/896	222/18722	2.37010821662331e-05	0.000230409959526315	FCER1G/SERPINA1/PLEK/LYN/FLNA/CD36/ACTB/WAS/PLAUR/PTPN6/JAK2/FERMT3/SYK/PLSCR1/TLR4/ENTPD1/RAB27A/SH2B3/JMJD1C/TLN1/CLIC1/GNAQ/DGKZ/MYH9/RAP2B/BLOC1S6	26
GO:0051222	positive regulation of protein transport	32/896	303/18722	2.41260227430109e-05	0.000234103440832835	IL1B/ITGB2/FLNA/HLA-DRB1/PTGS2/RAC2/JAK2/TLR2/TGFB1/OAZ1/SORL1/TNF/ITGAM/TLR4/CD33/FYN/SERP1/GLUL/HCLS1/NADK/CHP1/PAK1/CDC42/PRKACA/UBE2D3/HIF1A/TOMM7/MAPK1/ACSL4/IRS2/PRNP/CIB1	32
GO:0002577	regulation of antigen processing and presentation	7/896	20/18722	2.5158082378836e-05	0.000242759158538638	FGL2/CD74/PYCARD/SLC11A1/LILRB2/CD68/WAS	7
GO:0072567	chemokine (C-X-C motif) ligand 2 production	7/896	20/18722	2.5158082378836e-05	0.000242759158538638	CD74/KLF4/OAS1/TNF/MYD88/TLR4/MBP	7
GO:2000341	regulation of chemokine (C-X-C motif) ligand 2 production	7/896	20/18722	2.5158082378836e-05	0.000242759158538638	CD74/KLF4/OAS1/TNF/MYD88/TLR4/MBP	7
GO:0002467	germinal center formation	6/896	14/18722	2.54807890070208e-05	0.000245417747454657	TNFSF13B/TNFAIP3/MEF2C/BCL6/PKN1/ADAM17	6
GO:0045582	positive regulation of T cell differentiation	15/896	91/18722	2.5596063389979e-05	0.00024583336536891	PTPRC/HLA-DRA/CD74/NFKBIZ/HLA-DRB1/LILRB2/CD83/LGALS9/NCKAP1L/SYK/CD86/NLRP3/RHOA/BCL6/TGFBR2	15
GO:0019724	B cell mediated immunity	25/896	210/18722	2.56184741453469e-05	0.00024583336536891	FCER1G/PTPRC/HLA-DRA/CD74/HLA-DPA1/B2M/HLA-DPB1/HLA-DRB1/HLA-E/HLA-DQB1/HLA-DMA/HLA-DMB/PTPN6/TGFB1/TLR8/TNF/MYD88/TCIRG1/STAT6/GAPT/HLA-DQA1/IRF7/INPP5D/BCL6/BTK	25
GO:0090316	positive regulation of intracellular protein transport	21/896	160/18722	2.62033938375964e-05	0.000250983151656241	IL1B/ITGB2/FLNA/PTGS2/RAC2/JAK2/TGFB1/OAZ1/SORL1/ITGAM/FYN/HCLS1/CHP1/PAK1/CDC42/PRKACA/UBE2D3/TOMM7/MAPK1/PRNP/CIB1	21
GO:0002719	negative regulation of cytokine production involved in immune response	8/896	27/18722	2.62529408988243e-05	0.000250995488262473	BST2/IRAK3/LILRB1/HLA-F/TGFB1/TNF/BCL6/HMOX1	8
GO:0002861	regulation of inflammatory response to antigenic stimulus	10/896	43/18722	2.71937689867299e-05	0.000259513380733912	LYN/FGR/HLA-DRB1/HLA-E/HCK/GPX1/SYK/TNF/FYN/BTK	10
GO:0046640	regulation of alpha-beta T cell proliferation	9/896	35/18722	2.89861408529466e-05	0.000276111572483837	PTPRC/HLA-A/IRF1/HLA-E/LGALS9/SYK/CCR2/TNFRSF14/TGFBR2	9
GO:0030522	intracellular receptor signaling pathway	29/896	265/18722	2.98041516630018e-05	0.000283384630346019	NFKBIA/KLF2/TNFAIP3/NR4A1/USP15/NR4A2/JAK2/RHOA/TLR4/BIRC3/IRF7/HSPA1A/AHR/PKN1/PAK1/DDX5/STAT3/CYLD/RXRA/NCOA4/CTBP2/PRCP/IFIH1/SEC14L1/ZBTB7A/ARID1A/NR3C1/EP300/BIRC2	29
GO:2001235	positive regulation of apoptotic signaling pathway	18/896	126/18722	3.11244968614387e-05	0.000295398737548071	S100A9/S100A8/PTPRC/PYCARD/MCL1/TNFSF10/CTSH/BID/TNF/STK4/SKIL/PAK2/PTEN/CYLD/ATF3/PTPN2/LTBR/PEA15	18
GO:0032623	interleukin-2 production	12/896	62/18722	3.17023602225068e-05	0.000299789046395015	IL1B/ZFP36/PTPRC/LAPTM5/CLEC7A/TNFAIP3/GBP1/CD83/CD4/CD86/CCR2/PRNP	12
GO:0032663	regulation of interleukin-2 production	12/896	62/18722	3.17023602225068e-05	0.000299789046395015	IL1B/ZFP36/PTPRC/LAPTM5/CLEC7A/TNFAIP3/GBP1/CD83/CD4/CD86/CCR2/PRNP	12
GO:0016049	cell growth	44/896	482/18722	3.22303686376338e-05	0.000304228942439806	S100A9/S100A8/CYBA/RGS2/BST2/ITGA4/IQGAP1/PPT1/TGFB1/CDA/HBEGF/CXCR4/RHOA/RASGRP2/BCL6/ARHGAP4/PTK2B/FBP1/DPYSL2/AKAP13/HSPA1A/G6PD/BTG1/NIN/OGFR/C9orf72/SHTN1/PAK1/MTPN/SGK1/RPS6KA3/TWF2/CDKN1A/CDC42/ITSN2/SDCBP/RB1/ADAM10/DBNL/TGFBR2/LAMTOR1/ADAM17/DDX3X/CIB1	44
GO:0002534	cytokine production involved in inflammatory response	13/896	72/18722	3.25746323633115e-05	0.000306366479062537	PYCARD/CLEC7A/GPSM3/IL17RA/GBP5/TNF/MYD88/ALOX5/TLR4/STAT3/SIRPA/ADCY7/HIF1A	13
GO:1900015	regulation of cytokine production involved in inflammatory response	13/896	72/18722	3.25746323633115e-05	0.000306366479062537	PYCARD/CLEC7A/GPSM3/IL17RA/GBP5/TNF/MYD88/ALOX5/TLR4/STAT3/SIRPA/ADCY7/HIF1A	13
GO:0031295	T cell costimulation	10/896	44/18722	3.36955034888345e-05	0.000315766330892663	LGALS1/TNFSF13B/LYN/LILRB2/PTPN6/CD86/CSK/TNFRSF14/FYN/MAP3K8	10
GO:0062208	positive regulation of pattern recognition receptor signaling pathway	10/896	44/18722	3.36955034888345e-05	0.000315766330892663	CYBA/USP15/TLR2/TLR4/TLR1/HSPA1A/IFI35/PJA2/DDX3X/NINJ1	10
GO:0043620	regulation of DNA-templated transcription in response to stress	11/896	53/18722	3.40898020065745e-05	0.00031888679898596	KLF2/EGR1/CEBPB/BACH1/JUN/HSPA1A/RPS6KA3/HIF1A/ATF3/HMOX1/TMBIM6	11
GO:0045861	negative regulation of proteolysis	35/896	351/18722	3.45447982778663e-05	0.000322562829161908	SERPINA1/CST3/CD44/CARD16/CSTA/TIMP1/LRRK2/KLF4/IFI16/PTGS2/BST2/ARRB2/NR4A1/NAIP/PLAUR/GPX1/CTSZ/SORL1/TNF/BIRC3/SERPINB1/TIMP2/PICALM/RPS6KA3/PAK2/CSTB/ROCK1/SDCBP/CAST/CARD8/WAC/DDX3X/PRNP/HERPUD1/BIRC2	35
GO:0002507	tolerance induction	8/896	28/18722	3.52197804150073e-05	0.00032827612533773	HLA-B/LYN/TNFAIP3/HLA-E/LILRB2/IRAK3/LGALS9/TGFBR2	8
GO:0044409	entry into host	20/896	151/18722	3.54540852856882e-05	0.000329868868641975	FCN1/CD74/IFITM3/LGALS1/HLA-DRB1/CXCL8/IFITM2/LGALS9/TRIM22/CD4/CD86/PLSCR1/CXCR4/SELPLG/TNFRSF14/CTSB/HSPA1A/TRIM38/ITGA5/DYNLT1	20
GO:0045655	regulation of monocyte differentiation	7/896	21/18722	3.61823434229902e-05	0.000335444506493711	CD74/HLA-DRB1/CD4/IRF7/INPP5D/JUN/ZFP36L1	7
GO:0046641	positive regulation of alpha-beta T cell proliferation	7/896	21/18722	3.61823434229902e-05	0.000335444506493711	PTPRC/HLA-A/HLA-E/LGALS9/SYK/CCR2/TGFBR2	7
GO:0050854	regulation of antigen receptor-mediated signaling pathway	12/896	63/18722	3.74764490195276e-05	0.000346823863613101	PTPRC/LAPTM5/LYN/GBP1/PTPN6/PRKCB/NFAM1/CD300A/CMTM3/DGKZ/PTPN2/PRNP	12
GO:0070228	regulation of lymphocyte apoptotic process	11/896	54/18722	4.09786295770141e-05	0.000378561016749646	CD74/TSC22D3/LYN/LGALS9/GIMAP8/BCL6/BTK/DOCK8/PTEN/HIF1A/IRS2	11
GO:0032869	cellular response to insulin stimulus	24/896	203/18722	4.13389941049979e-05	0.000381212958049812	IL1B/GNAI2/STAT1/SOCS3/PTPRE/UCP2/PRKCB/SORL1/ZFP36L1/OSBPL8/PDK4/RAB8B/RHOQ/PAK1/GRB2/CFLAR/PTEN/ZNF106/PIP4K2A/IRS2/PHIP/RAB10/PTPN2/SP1	24
GO:0035307	positive regulation of protein dephosphorylation	10/896	45/18722	4.14813934609999e-05	0.000381849075027718	PTPRC/LILRB2/JAK2/TGFB1/CD33/CD300A/PPP1R15A/CALM2/PPP1R15B/PPP1R12A	10
GO:0010720	positive regulation of cell development	31/896	298/18722	4.29930579998477e-05	0.000394368420912183	TYROBP/IL1B/TSPO/TNFRSF1B/CLEC7A/LYN/FLNA/ACTR2/CX3CR1/MYADM/TLR2/TGFB1/NUMB/CXCR4/PLXNC1/TNF/PREX1/TRIB1/SKIL/NIN/SHTN1/PAK1/TWF2/CDC42/LIMS1/HIF1A/PLXNB2/DBNL/SPEN/DICER1/CIB1	31
GO:0031647	regulation of protein stability	31/896	298/18722	4.29930579998477e-05	0.000394368420912183	TYROBP/PYCARD/LRRK2/FLNA/IFI30/GRN/CTSH/RNF149/USP3/RASSF2/HSPA1A/STK4/MFSD1/CHP1/GNAQ/PTEN/PFN1/CRTAP/TOMM7/MAPK1/MDM4/CTSA/PRNP/CREBBP/EP300/CMTM6/LAMP2/ZNF207/MORC3/STX12/CREB1	31
GO:0016241	regulation of macroautophagy	19/896	141/18722	4.33877478388384e-05	0.000397288162869364	LRRK2/VPS13C/SPTLC2/RALB/CAPNS1/ATP6V1B2/C9orf72/PRKACA/ATP6V0D1/BNIP3L/ATP6V1A/ATP6V0B/HIF1A/HMOX1/PIP4K2A/CALCOCO2/GNAI3/WAC/SMG1	19
GO:0014706	striated muscle tissue development	37/896	384/18722	4.36836381767974e-05	0.000399294555637124	FOS/RGS2/VAMP5/EGR1/BTG2/ARRB2/NR4A1/MEF2C/GPCPD1/GPX1/TGFB1/NOTCH2/SLC8A1/RHOA/AKAP13/FKBP1A/MEF2A/G6PD/FOXN2/PAK1/MTPN/CDC42/PRKAR1A/DDX5/KDM6B/CFLAR/PTEN/RB1/MAPK1/ATF3/TGFBR2/HNRNPU/EEF2/PPP3CA/PLEC/EP300/CREB1	37
GO:0001667	ameboidal-type cell migration	43/896	475/18722	4.80333387289142e-05	0.000438283148647513	TMSB4X/ZEB2/ARHGDIB/TIMP1/KLF4/RHOB/PTGS2/CYP1B1/NR4A1/MEF2C/GLIPR2/ITGA4/GPX1/GRN/CTSH/CAP1/TGFB1/HBEGF/SLC8A1/TNF/RHOA/ARHGAP4/MAP3K3/PTK2B/GLUL/PKN1/SP100/PAK1/ZFAND5/RRAS/ROCK1/PTEN/PFN1/HIF1A/PRCP/HMOX1/TGFBR2/CORO1C/MYH9/SP1/ADAM17/PLEC/CIB1	43
GO:0038066	p38MAPK cascade	11/896	55/18722	4.90322959348515e-05	0.000445833865659375	IL1B/NCF1/ZFP36/DUSP1/SPI1/GADD45B/LGALS9/MAP3K3/ZFP36L1/CYLD/PJA2	11
GO:0061614	pri-miRNA transcription by RNA polymerase II	11/896	55/18722	4.90322959348515e-05	0.000445833865659375	FOS/SPI1/EGR1/KLF4/TGFB1/TNF/JUN/DDX5/STAT3/HIF1A/NR3C1	11
GO:0031294	lymphocyte costimulation	10/896	46/18722	5.07520718685863e-05	0.000459863285345849	LGALS1/TNFSF13B/LYN/LILRB2/PTPN6/CD86/CSK/TNFRSF14/FYN/MAP3K8	10
GO:0061028	establishment of endothelial barrier	10/896	46/18722	5.07520718685863e-05	0.000459863285345849	IL1B/MSN/PECAM1/MYADM/TNF/MYD88/RAP1A/TNFRSF1A/ROCK1/RAP1B	10
GO:0002292	T cell differentiation involved in immune response	13/896	75/18722	5.09396474905389e-05	0.000460760185388336	FGL2/FCER1G/HLA-DRA/NFKBIZ/HLA-DRB1/LGALS9/CD86/NLRP3/STAT6/IL6R/SPN/BCL6/STAT3	13
GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	5/896	10/18722	5.11522158803094e-05	0.000461879643738697	PTPRC/LYN/PLSCR1/CSK/RAP1A	5
GO:0016311	dephosphorylation	39/896	417/18722	5.29369291729351e-05	0.000477166323446162	DUSP1/PTPRC/DUSP6/LRRK2/PLEK/GNAI2/LILRB2/MEF2C/PTPN6/PTPRE/JAK2/PTP4A2/NCKAP1L/TGFB1/DAPP1/TNF/CD33/CD300A/INPP5D/FBP1/FKBP1A/PTPN18/PPP1R15A/NUDT16/CALM2/CHP1/CPPED1/ROCK1/YWHAB/PTEN/BOD1L1/PPP1R15B/SSH2/DUSP23/PPP3CA/DUSP22/PTPN2/PPP1R12A/CTDSP1	39
GO:0060761	negative regulation of response to cytokine stimulus	14/896	86/18722	5.44933497397971e-05	0.000490345868506375	PTPRC/SAMHD1/CARD16/KLF4/ISG15/IRAK3/IL1RN/STAT2/OAS1/SH2B3/PARP14/CARD8/ADAR/PTPN2	14
GO:0060537	muscle tissue development	38/896	403/18722	5.52274297156833e-05	0.000496093025822572	FOS/RGS2/VAMP5/EGR1/BTG2/ARRB2/NR4A1/MEF2C/GPCPD1/GPX1/TGFB1/NOTCH2/SLC8A1/RHOA/AKAP13/FKBP1A/MEF2A/G6PD/FOXN2/PAK1/MTPN/CDC42/PRKAR1A/DDX5/ZFAND5/KDM6B/CFLAR/PTEN/RB1/MAPK1/ATF3/TGFBR2/HNRNPU/EEF2/PPP3CA/PLEC/EP300/CREB1	38
GO:0046718	viral entry into host cell	19/896	144/18722	5.8147289308535e-05	0.000521420778782225	FCN1/CD74/IFITM3/LGALS1/HLA-DRB1/IFITM2/LGALS9/TRIM22/CD4/CD86/PLSCR1/CXCR4/SELPLG/TNFRSF14/CTSB/HSPA1A/TRIM38/ITGA5/DYNLT1	19
GO:0002711	positive regulation of T cell mediated immunity	11/896	56/18722	5.84089930588656e-05	0.000522866046298038	IL1B/HLA-B/PTPRC/HLA-A/HLA-DRA/B2M/HLA-DRB1/HLA-E/HLA-F/NLRP3/STX7	11
GO:0032715	negative regulation of interleukin-6 production	12/896	66/18722	6.05968261084931e-05	0.000540810543219941	KLF2/TNFAIP3/ARRB2/IRAK3/PTPN6/NCKAP1L/CSK/TNF/TLR4/INPP5D/CD84/SIRPA	12
GO:0051656	establishment of organelle localization	37/896	390/18722	6.06215240717604e-05	0.000540810543219941	STXBP2/LRRK2/LYN/FGR/MYO1F/ACTR2/RAC2/ITGA4/LGALS9/SYK/MYO1G/LAT2/TCIRG1/RAB27A/ADGRE2/CD300A/BTK/BLOC1S1/ACTR3/AGTPBP1/CFL1/CD84/CHP1/PICALM/CDC42/HIF1A/SUN2/BICD2/HMOX1/HNRNPU/MYH9/DYNLT1/CHMP1B/NUP62/HOOK3/FAM91A1/BLOC1S6	37
GO:0045577	regulation of B cell differentiation	8/896	30/18722	6.09058174129293e-05	0.000542416363638091	ZFP36L2/PTPN6/NCKAP1L/SYK/NFAM1/INPP5D/BTK/ZFP36L1	8
GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	10/896	47/18722	6.1730994040798e-05	0.000548825470096052	KLF2/EGR1/CEBPB/BACH1/JUN/HSPA1A/HIF1A/ATF3/HMOX1/TMBIM6	10
GO:0051014	actin filament severing	6/896	16/18722	6.25616455959387e-05	0.000553372650925982	GMFG/FMNL1/CAPG/CFL1/FLII/MYH9	6
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	6/896	16/18722	6.25616455959387e-05	0.000553372650925982	NAMPT/LRRK2/STAT1/JAK2/TLR2/TLR4	6
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	6/896	16/18722	6.25616455959387e-05	0.000553372650925982	IL1B/CLEC7A/LGALS9/SYK/OAS1/CD84	6
GO:1904951	positive regulation of establishment of protein localization	32/896	319/18722	6.58774622762561e-05	0.000581712531916482	IL1B/ITGB2/FLNA/HLA-DRB1/PTGS2/RAC2/JAK2/TLR2/TGFB1/OAZ1/SORL1/TNF/ITGAM/TLR4/CD33/FYN/SERP1/GLUL/HCLS1/NADK/CHP1/PAK1/CDC42/PRKACA/UBE2D3/HIF1A/TOMM7/MAPK1/ACSL4/IRS2/PRNP/CIB1	32
GO:0072594	establishment of protein localization to organelle	39/896	422/18722	6.85467227400943e-05	0.000604256788086831	TXNIP/TSPO/LAPTM5/NFKBIA/LRRK2/FLNA/CD36/NUP214/PTGS2/TNFAIP3/CD68/RAC2/JAK2/VPS13C/IL10RA/TGFB1/SYK/SORL1/BID/HCLS1/RAB8B/CHP1/CDKN1A/BNIP3L/STAT3/UBE2D3/TOMM7/MAPK1/NCOA4/NIPBL/M6PR/NUP50/OXA1L/PPP3CA/RAB10/SPCS3/NUP62/HERPUD1/LAMP2	39
GO:0033619	membrane protein proteolysis	11/896	57/18722	6.92828847748866e-05	0.000609712832003698	IL1B/TNFRSF1B/TIMP1/CTSH/TGFB1/TNF/TIMP2/ROCK1/ADAM10/MYH9/ADAM17	11
GO:0045580	regulation of T cell differentiation	19/896	146/18722	7.03126321826815e-05	0.000617729729699538	FGL2/PTPRC/HLA-DRA/CD74/IRF1/NFKBIZ/HLA-DRB1/LILRB2/CD83/LGALS9/NCKAP1L/SYK/CD86/NLRP3/CCR2/RHOA/BCL6/TGFBR2/PTPN2	19
GO:0051048	negative regulation of secretion	21/896	171/18722	7.0651811933696e-05	0.00061966285643702	IL1B/CD74/TNFRSF1B/SPI1/GNAI2/LILRB1/LGALS9/HLA-F/UCP2/NCKAP1L/CCR2/CD300A/MIDN/CD84/RAP1A/TNFRSF1A/RAP1B/RAB11FIP1/HMOX1/PPP3CA/WNK1	21
GO:0031396	regulation of protein ubiquitination	24/896	210/18722	7.13301735678822e-05	0.00062455931435447	TSPO/LAPTM5/LRRK2/ISG15/TNFAIP3/ARRB2/BIRC3/FYN/RASSF5/UBE2D1/HSPA1A/FKBP1A/DTX3L/GABARAP/CHP1/SPOPL/IVNS1ABP/PTEN/MYCBP2/NMI/DDX3X/HERPUD1/TRIP12/BIRC2	24
GO:0002701	negative regulation of production of molecular mediator of immune response	9/896	39/18722	7.3234229782212e-05	0.000636941854677733	BST2/IRAK3/LILRB1/HLA-F/TGFB1/TNF/BCL6/HMOX1/TMBIM6	9
GO:0034314	Arp2/3 complex-mediated actin nucleation	9/896	39/18722	7.3234229782212e-05	0.000636941854677733	GMFG/ACTR2/WAS/ARPC1B/ARPC3/ACTR3/ARPC4/ARPC5/BRK1	9
GO:2000249	regulation of actin cytoskeleton reorganization	9/896	39/18722	7.3234229782212e-05	0.000636941854677733	GMFG/ARHGDIB/HCK/NOTCH2/CSF1R/PTK2B/HCLS1/CDC42/ARHGDIA	9
GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	9/896	39/18722	7.3234229782212e-05	0.000636941854677733	HLA-DRA/NFKBIZ/HLA-DRB1/CD83/LGALS9/NCKAP1L/CD86/NLRP3/TGFBR2	9
GO:0050878	regulation of body fluid levels	36/896	379/18722	7.40379338354479e-05	0.000642856917993597	CYBA/FCER1G/SERPINA1/PLEK/LYN/FLNA/CD36/ACTB/GNAI2/WAS/PLAUR/PTPN6/JAK2/FERMT3/SYK/PLSCR1/OAS2/FLI1/TLR4/ENTPD1/RAB27A/SH2B3/JMJD1C/TLN1/PRKACA/CLIC1/GNAQ/HIF1A/DGKZ/MYH9/RAP2B/PLEC/USF2/WNK1/BLOC1S6/CREB1	36
GO:1903531	negative regulation of secretion by cell	19/896	147/18722	7.72012186241764e-05	0.000669205896773903	IL1B/TNFRSF1B/SPI1/GNAI2/LILRB1/LGALS9/HLA-F/UCP2/NCKAP1L/CCR2/CD300A/MIDN/CD84/RAP1A/TNFRSF1A/RAP1B/RAB11FIP1/HMOX1/PPP3CA	19
GO:0030168	platelet activation	17/896	123/18722	7.83083071966306e-05	0.000677673054458695	FCER1G/PLEK/LYN/FLNA/ACTB/PTPN6/JAK2/FERMT3/SYK/PLSCR1/TLR4/SH2B3/TLN1/CLIC1/DGKZ/MYH9/RAP2B	17
GO:0042987	amyloid precursor protein catabolic process	12/896	68/18722	8.20980593563024e-05	0.000708112780617129	LYN/SORL1/TNF/FKBP1A/IFNGR1/PICALM/RTN3/ROCK1/ADAM10/SP1/ADAM17/PRNP	12
GO:0046637	regulation of alpha-beta T cell differentiation	12/896	68/18722	8.20980593563024e-05	0.000708112780617129	HLA-DRA/NFKBIZ/HLA-DRB1/CD83/LGALS9/NCKAP1L/SYK/CD86/NLRP3/RHOA/BCL6/TGFBR2	12
GO:0002526	acute inflammatory response	16/896	112/18722	8.44646248827993e-05	0.000727318731813641	S100A8/IL1B/SERPINA1/PTGS2/HLA-E/CEBPB/NLRP3/PLSCR1/TREM1/TNF/IL6R/BTK/CD163/ALOX5AP/STAT3/PRCP	16
GO:0031331	positive regulation of cellular catabolic process	39/896	427/18722	8.82306189144852e-05	0.000758491651197086	IL1B/ZFP36/LAPTM5/ZFP36L2/TNFRSF1B/LRRK2/MSN/BTG2/PABPC1/TNFAIP3/MTDH/TRIM22/BID/TNF/PTK2B/ZFP36L1/HSPA1A/FBXL5/SPTLC2/TRIM38/AGTPBP1/RALB/TRIB1/DTX3L/GABARAP/C9orf72/BNIP3L/ROCK1/PTEN/HIF1A/PIAS1/HMOX1/PIP4K2A/CALCOCO2/IRS2/GNAI3/WAC/CELF1/HERPUD1	39
GO:0031346	positive regulation of cell projection organization	34/896	353/18722	8.86539206917277e-05	0.000760873005804746	S100A9/RGS2/LYN/FLNA/ACTR2/RAC2/IQGAP1/GRN/CCDC88A/PLXNC1/FYN/DOCK11/PTK2B/SETX/ACTR3/ARAP1/CDC42EP3/SKIL/RAB8B/NIN/RAP1A/SHTN1/RHOQ/PAK1/TWF2/CDC42/CFLAR/PFN1/PLXNB2/DBNL/BRK1/CORO1C/DYNLT1/EP300	34
GO:0034115	negative regulation of heterotypic cell-cell adhesion	5/896	11/18722	9.0080344538298e-05	0.000766237688385053	KLF4/IL1RN/MYADM/MBP/WNK1	5
GO:0045657	positive regulation of monocyte differentiation	5/896	11/18722	9.0080344538298e-05	0.000766237688385053	CD74/HLA-DRB1/CD4/JUN/ZFP36L1	5
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	5/896	11/18722	9.0080344538298e-05	0.000766237688385053	KLF4/IL1RN/MYADM/MBP/WNK1	5
GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	5/896	11/18722	9.0080344538298e-05	0.000766237688385053	CD36/GBP5/MYD88/TLR4/DDX3X	5
GO:0030866	cortical actin cytoskeleton organization	9/896	40/18722	9.05189592599391e-05	0.000766237688385053	LCP1/PLEK/FMNL1/NCKAP1L/TNF/TLN1/RHOQ/ROCK1/PLEC	9
GO:1901223	negative regulation of NIK/NF-kappaB signaling	9/896	40/18722	9.05189592599391e-05	0.000766237688385053	TMSB4X/SPI1/NLRP3/RASSF2/IFI35/LITAF/CYLD/NMI/DDX3X	9
GO:0045638	negative regulation of myeloid cell differentiation	14/896	90/18722	9.0899568108744e-05	0.000766237688385053	ZFP36/NFKBIA/CCL3/LYN/LILRB3/MAFB/LILRB1/TLR4/INPP5D/PTK2B/ZFP36L1/TRIB1/PTPN2/CIB1	14
GO:0046849	bone remodeling	14/896	90/18722	9.0899568108744e-05	0.000766237688385053	SNX10/TNFAIP3/RAC2/TPP1/TGFB1/SYK/NOTCH2/CSF1R/CSK/RASSF2/TCIRG1/INPP5D/PTK2B/PDK4	14
GO:0061097	regulation of protein tyrosine kinase activity	14/896	90/18722	9.0899568108744e-05	0.000766237688385053	NCF1/PTPRC/FCGR1A/HBEGF/CSF1R/LILRA5/PAK2/DUSP22/PTPN2/ABI1/RAP2B/ADAM17/MVP/PRNP	14
GO:0097581	lamellipodium organization	14/896	90/18722	9.0899568108744e-05	0.000766237688385053	CD44/PLEKHO1/ACTR2/WAS/RAC2/CCDC88A/ACTR3/TWF2/CDC42/ARPC5/BRK1/CORO1C/ABI1/SNX2	14
GO:1904705	regulation of vascular associated smooth muscle cell proliferation	14/896	90/18722	9.0899568108744e-05	0.000766237688385053	SOD2/GNAI2/MEF2C/JAK2/TNF/RHOA/JUN/PAK1/CDKN1A/PTEN/HMOX1/NQO2/GNAI3/GNA13	14
GO:0048545	response to steroid hormone	33/896	339/18722	9.1397404946379e-05	0.000769187545511516	AIF1/CYBB/CYBA/FOS/TXNIP/TSPO/ZFP36/DUSP1/ZFP36L2/FOSB/PTGS2/JAK2/IL1RN/TLR2/TGFB1/TNF/RHOA/PTAFR/ZFP36L1/PKN1/PAK1/CDKN1A/DDX5/CFLAR/HNMT/RXRA/NCOA4/ZBTB7A/ARID1A/TGFBR2/HNRNPU/NR3C1/EP300	33
GO:0016045	detection of bacterium	6/896	17/18722	9.27796328269482e-05	0.000779558756596054	HLA-B/HLA-A/HLA-DRB1/NAIP/TLR2/TLR1	6
GO:0031667	response to nutrient levels	42/896	474/18722	9.486691052445e-05	0.000792613991744571	CYBB/CYBA/TSPO/ZFP36/SOD2/NAMPT/LRRK2/IFI16/GNAI2/PTGS2/STAT1/CD68/UCP2/SORL1/SLC8A1/UPP1/APAF1/KYNU/JUN/ACSL1/EIF4EBP1/GLUL/RALB/PDK4/G6PD/GABARAP/PRKAG2/CDKN1A/PTEN/KLF10/MAPK1/ACSL4/ATF3/BNIP2/HMOX1/MBD2/TGFBR2/EEF2/MAX/PLEC/USF2/LAMP2	42
GO:0001783	B cell apoptotic process	7/896	24/18722	9.49429949734412e-05	0.000792613991744571	CD74/LYN/BCL6/BTK/PKN1/PTEN/IRS2	7
GO:0007035	vacuolar acidification	7/896	24/18722	9.49429949734412e-05	0.000792613991744571	SLC11A1/DMXL2/PPT1/GRN/TCIRG1/ATP6V0D1/ATP6AP2	7
GO:0035458	cellular response to interferon-beta	7/896	24/18722	9.49429949734412e-05	0.000792613991744571	MNDA/IRF1/IFI16/STAT1/IFITM2/OAS1/CAPN2	7
GO:0048278	vesicle docking	11/896	59/18722	9.63046480806328e-05	0.000802693068377197	STXBP2/PLEK/STX11/STX10/RALB/RAB8B/CTBP2/RAB10/STX7/STX12/BLOC1S6	11
GO:0001558	regulation of cell growth	38/896	414/18722	9.76045023356877e-05	0.000812225626636658	S100A9/S100A8/CYBA/RGS2/BST2/PPT1/TGFB1/CDA/HBEGF/CXCR4/RHOA/RASGRP2/BCL6/ARHGAP4/PTK2B/FBP1/DPYSL2/HSPA1A/G6PD/BTG1/OGFR/SHTN1/PAK1/MTPN/SGK1/RPS6KA3/TWF2/CDKN1A/CDC42/ITSN2/SDCBP/RB1/ADAM10/DBNL/LAMTOR1/ADAM17/DDX3X/CIB1	38
GO:0035710	CD4-positive, alpha-beta T cell activation	15/896	102/18722	9.97995235599097e-05	0.000827842618875742	HLA-DRA/NFKBIZ/HLA-DRB1/CD83/LGALS9/NCKAP1L/CD86/NLRP3/TCIRG1/STAT6/IL6R/SPN/BCL6/STAT3/TGFBR2	15
GO:1902106	negative regulation of leukocyte differentiation	15/896	102/18722	9.97995235599097e-05	0.000827842618875742	FGL2/CD74/CCL3/IRF1/LYN/LILRB3/MAFB/TMEM176B/LILRB1/TLR4/TMEM176A/INPP5D/BCL6/TRIB1/PTPN2	15
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	8/896	32/18722	0.000100524416542722	0.000832527851017037	HLA-DRA/NFKBIZ/HLA-DRB1/CD83/LGALS9/NCKAP1L/CD86/NLRP3	8
GO:0046700	heterocycle catabolic process	40/896	445/18722	0.000101717231321007	0.000841067281558911	TYMP/ZFP36/APOBEC3A/VIM/SAMHD1/ZFP36L2/TNFRSF1B/SLC11A1/BTG2/PABPC1/DPYD/RNASET2/BLVRB/CDA/RNASE6/OAS2/MYD88/UPP1/ENTPD1/KYNU/ZFP36L1/HSPA1A/NUDT16/BLVRA/DDX5/ROCK1/MGAT1/HNMT/NUDT3/ATM/HMOX1/TET2/YBX1/HNRNPU/DICER1/XRN2/CELF1/RNH1/XRN1/SMG1	40
GO:1990874	vascular associated smooth muscle cell proliferation	14/896	91/18722	0.000102772932603064	0.000848447654711965	SOD2/GNAI2/MEF2C/JAK2/TNF/RHOA/JUN/PAK1/CDKN1A/PTEN/HMOX1/NQO2/GNAI3/GNA13	14
GO:0010631	epithelial cell migration	34/896	357/18722	0.000110414140593204	0.000910085491640659	TMSB4X/ZEB2/KLF4/RHOB/PTGS2/CYP1B1/NR4A1/MEF2C/GLIPR2/GPX1/GRN/CTSH/TGFB1/HBEGF/TNF/RHOA/MAP3K3/PTK2B/GLUL/PKN1/SP100/RRAS/ROCK1/PTEN/PFN1/HIF1A/PRCP/HMOX1/TGFBR2/CORO1C/MYH9/SP1/ADAM17/CIB1	34
GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	11/896	60/18722	0.000112889534505666	0.000929016564816405	NFKBIA/TNFAIP3/USP15/TLR4/BIRC3/IRF7/HSPA1A/CYLD/IFIH1/SEC14L1/BIRC2	11
GO:0006605	protein targeting	31/896	314/18722	0.00011422218289544	0.000938498535922882	ITGB2/NCF1/TSPO/LAPTM5/LRRK2/RAC2/VPS13C/SORL1/BID/ITGAM/RAB27A/FYN/GABARAP/RAB8B/CHP1/PAK1/ATG3/BNIP3L/YWHAB/SDCBP/UBE2D3/TOMM7/NCOA4/ZDHHC20/M6PR/SSR1/PRNP/SPCS3/HERPUD1/LAMP2/CIB1	31
GO:0001960	negative regulation of cytokine-mediated signaling pathway	13/896	81/18722	0.000115908565840245	0.000950852446269894	PTPRC/SAMHD1/CARD16/ISG15/IRAK3/IL1RN/STAT2/OAS1/SH2B3/PARP14/CARD8/ADAR/PTPN2	13
GO:0071453	cellular response to oxygen levels	21/896	177/18722	0.00011635756192358	0.000953032566243372	CYBB/CARD16/NAMPT/EGR1/PTGS2/BACH1/SLC8A1/ZFP36L1/EIF4EBP1/MALAT1/ATP6V0D1/BNIP3L/ATP6V1A/CFLAR/PTEN/HIF1A/PGK1/GNB1/HMOX1/MDM4/TMBIM6	21
GO:0006898	receptor-mediated endocytosis	26/896	244/18722	0.000117410684414487	0.000960146178678847	FCER1G/ITGB2/CD14/B2M/CD36/ARRB2/CXCL8/ASGR1/ITGA4/LILRB1/PPT1/CAP1/SYK/NUMB/SORL1/ITGAM/RIN3/ANKRD13D/PICALM/GRB2/ITSN2/SDCBP/BMP2K/DBNL/M6PR/TGFBR2	26
GO:0018105	peptidyl-serine phosphorylation	31/896	315/18722	0.000121047383991223	0.000988331937422843	CD44/LRRK2/PTGS2/ARRB2/PRKCB/TGFB1/SYK/RASSF2/TNF/MAPKAPK3/HCLS1/PKN1/STK4/PAK1/SGK1/RPS6KA3/PAK2/PRKACA/ROCK1/STK38/PTEN/HIPK3/MAPK1/ATM/TGFBR2/CLK1/CAB39/HIPK1/WNK1/SMG1/MORC3	31
GO:0042063	gliogenesis	30/896	301/18722	0.000123605074176438	0.00100763321440698	S100A9/S100A8/IL1B/TSPO/VIM/TNFRSF1B/CCL3/C5AR1/LYN/CX3CR1/GRN/TLR2/TGFB1/CCR2/CSK/CXCR4/TNF/RHOA/TLR4/PTK2B/IFNGR1/STAT3/PTEN/MAPK1/SUN2/MBOAT7/EEF2/DICER1/PLEC/CREB1	30
GO:0032753	positive regulation of interleukin-4 production	7/896	25/18722	0.000126448202387417	0.00102066121978141	FCER1G/HLA-E/CEBPB/LGALS9/SYK/CD86/NLRP3	7
GO:0042832	defense response to protozoan	7/896	25/18722	0.000126448202387417	0.00102066121978141	CLEC7A/SLC11A1/LYST/GBP2/GBP4/MYD88/IRF8	7
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	7/896	25/18722	0.000126448202387417	0.00102066121978141	NFKBIA/TNFAIP3/TLR4/BIRC3/HSPA1A/CYLD/BIRC2	7
GO:1901623	regulation of lymphocyte chemotaxis	7/896	25/18722	0.000126448202387417	0.00102066121978141	CCL3/CCR2/CCL4/PTK2B/ADAM10/ADAM17/WNK1	7
GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	7/896	25/18722	0.000126448202387417	0.00102066121978141	ITGB2/ITGA4/CCR2/TNF/ALOX5/RHOA/PTAFR	7
GO:0031333	negative regulation of protein-containing complex assembly	18/896	140/18722	0.000126450183829496	0.00102066121978141	TMSB4X/TMSB10/MYADM/SORL1/CAPG/EIF4EBP1/CAPZA1/MTPN/CAPZA2/TWF2/CDC42/PFN1/CARD8/FLII/SSH2/DDX3X/EP300/BIRC2	18
GO:0045927	positive regulation of growth	27/896	259/18722	0.000126576905741013	0.00102066121978141	S100A9/S100A8/CYBA/MEF2C/HBEGF/CXCR4/RHOA/PTK2B/SERP1/SHTN1/PAK1/MTPN/RPS6KA3/TWF2/CDC42/ITSN2/SDCBP/ADAM10/MAPK1/NIPBL/DBNL/TGFBR2/CELF1/ADAM17/DDX3X/CREB1/CIB1	27
GO:0002335	mature B cell differentiation	8/896	33/18722	0.000127169455335168	0.0010222694547113	LGALS1/SPI1/NOTCH2/LFNG/DOCK11/IRF8/PTK2B/CMTM7	8
GO:0036336	dendritic cell migration	8/896	33/18722	0.000127169455335168	0.0010222694547113	SPI1/CCR1/LGALS9/CCR2/CXCR4/ALOX5/CDC42/DOCK8	8
GO:0008286	insulin receptor signaling pathway	16/896	116/18722	0.000129044451804885	0.00103574103987224	IL1B/GNAI2/SOCS3/PTPRE/PRKCB/SORL1/OSBPL8/PDK4/RHOQ/PAK1/GRB2/ZNF106/PIP4K2A/IRS2/PHIP/PTPN2	16
GO:0090132	epithelium migration	34/896	360/18722	0.00012977413622714	0.00103999273115155	TMSB4X/ZEB2/KLF4/RHOB/PTGS2/CYP1B1/NR4A1/MEF2C/GLIPR2/GPX1/GRN/CTSH/TGFB1/HBEGF/TNF/RHOA/MAP3K3/PTK2B/GLUL/PKN1/SP100/RRAS/ROCK1/PTEN/PFN1/HIF1A/PRCP/HMOX1/TGFBR2/CORO1C/MYH9/SP1/ADAM17/CIB1	34
GO:0032088	negative regulation of NF-kappaB transcription factor activity	14/896	93/18722	0.000130609909046337	0.00104347486474654	TMSB4X/PYCARD/NFKBIA/SPI1/KLF4/TNFAIP3/ARRB2/CYP1B1/IRAK3/NLRP3/CHP1/CYLD/CARD8/COMMD6	14
GO:0051591	response to cAMP	14/896	93/18722	0.000130609909046337	0.00104347486474654	FOS/DUSP1/FOSB/STAT1/SLC8A1/PTAFR/AQP9/JUN/PTK2B/ZFP36L1/AHR/RAP1A/RAP1B/BIRC2	14
GO:0002312	B cell activation involved in immune response	13/896	82/18722	0.000131806653149191	0.00105142086354132	PTPRC/LGALS1/SPI1/TGFB1/NOTCH2/LFNG/STAT6/TLR4/GAPT/DOCK11/BCL6/IRF8/PTK2B	13
GO:1900225	regulation of NLRP3 inflammasome complex assembly	6/896	18/18722	0.000133551567794637	0.00106370858208255	CD36/GBP5/MYD88/TLR4/CARD8/DDX3X	6
GO:0044270	cellular nitrogen compound catabolic process	40/896	451/18722	0.000135382442737863	0.00107664233131442	TYMP/ZFP36/APOBEC3A/VIM/SAMHD1/ZFP36L2/TNFRSF1B/SLC11A1/BTG2/PABPC1/DPYD/RNASET2/BLVRB/CDA/RNASE6/OAS2/MYD88/UPP1/ENTPD1/KYNU/ZFP36L1/HSPA1A/NUDT16/BLVRA/DDX5/ROCK1/MGAT1/HNMT/NUDT3/ATM/HMOX1/TET2/YBX1/HNRNPU/DICER1/XRN2/CELF1/RNH1/XRN1/SMG1	40
GO:0030307	positive regulation of cell growth	20/896	166/18722	0.000135773783036401	0.00107810602377453	S100A9/S100A8/CYBA/HBEGF/CXCR4/RHOA/PTK2B/SHTN1/PAK1/MTPN/RPS6KA3/TWF2/CDC42/ITSN2/SDCBP/ADAM10/DBNL/ADAM17/DDX3X/CIB1	20
GO:0033627	cell adhesion mediated by integrin	12/896	72/18722	0.00014532590074872	0.00115044141521171	ITGB2/LYN/CYP1B1/ITGA4/PTPN6/FERMT3/NCKAP1L/SYK/ITGA5/ADAM17/WNK1/CIB1	12
GO:0070227	lymphocyte apoptotic process	12/896	72/18722	0.00014532590074872	0.00115044141521171	CD74/TSC22D3/LYN/LGALS9/GIMAP8/BCL6/BTK/PKN1/DOCK8/PTEN/HIF1A/IRS2	12
GO:0033004	negative regulation of mast cell activation	5/896	12/18722	0.000148340128924403	0.00116896516747851	LGALS9/CD300LF/CD300A/CD84/HMOX1	5
GO:0060907	positive regulation of macrophage cytokine production	5/896	12/18722	0.000148340128924403	0.00116896516747851	LAPTM5/CD74/CD36/LILRB1/TLR4	5
GO:0070586	cell-cell adhesion involved in gastrulation	5/896	12/18722	0.000148340128924403	0.00116896516747851	KLF4/IL1RN/MYADM/MBP/WNK1	5
GO:0043367	CD4-positive, alpha-beta T cell differentiation	13/896	83/18722	0.000149547909725131	0.00117669996744388	HLA-DRA/NFKBIZ/HLA-DRB1/CD83/LGALS9/NCKAP1L/CD86/NLRP3/STAT6/IL6R/SPN/BCL6/STAT3	13
GO:0045010	actin nucleation	10/896	52/18722	0.000151857241894114	0.0011912662369401	CORO1A/GMFG/ACTR2/WAS/ARPC1B/ARPC3/ACTR3/ARPC4/ARPC5/BRK1	10
GO:1903426	regulation of reactive oxygen species biosynthetic process	10/896	52/18722	0.000151857241894114	0.0011912662369401	CYBA/SOD2/CD36/ALOX5/RHOA/TLR4/RAB27A/FYN/STAT3/CFLAR	10
GO:0070265	necrotic cell death	11/896	62/18722	0.000153447554519014	0.0012019288118274	TSPO/CASP1/TMEM123/TNF/BIRC3/CFLAR/CYLD/ASAH1/PYGL/NINJ1/BIRC2	11
GO:0046822	regulation of nucleocytoplasmic transport	15/896	106/18722	0.000155299145016899	0.00121277905890825	IL1B/FLNA/CD36/NUP214/PTGS2/JAK2/MX2/TGFB1/HCLS1/SP100/CHP1/PRKACA/MAPK1/PPP1R12A/NUP62	15
GO:1903707	negative regulation of hemopoiesis	15/896	106/18722	0.000155299145016899	0.00121277905890825	FGL2/CD74/CCL3/IRF1/LYN/LILRB3/MAFB/TMEM176B/LILRB1/TLR4/TMEM176A/INPP5D/BCL6/TRIB1/PTPN2	15
GO:0007519	skeletal muscle tissue development	19/896	155/18722	0.00015750907994841	0.00122819299072216	FOS/VAMP5/EGR1/BTG2/NR4A1/MEF2C/GPCPD1/GPX1/TGFB1/RHOA/FOXN2/DDX5/CFLAR/RB1/ATF3/EEF2/PPP3CA/PLEC/EP300	19
GO:0035308	negative regulation of protein dephosphorylation	8/896	34/18722	0.000159381276918746	0.00124039371319425	GNAI2/NCKAP1L/TNF/FKBP1A/PPP1R15A/ROCK1/YWHAB/BOD1L1	8
GO:0016236	macroautophagy	29/896	291/18722	0.000159550739113046	0.00124039371319425	VMP1/LRRK2/VPS13C/TCIRG1/ATG16L2/SPTLC2/RALB/CAPNS1/GABARAP/ATP6V1B2/C9orf72/PRKACA/ATP6V0D1/ATG3/BNIP3L/ATP6V1A/ATP6V0B/HIF1A/TOMM7/HMOX1/PIP4K2A/CALCOCO2/GNAI3/WAC/LAMP2/SMG1/RB1CC1/STX12/NBR1	29
GO:0006509	membrane protein ectodomain proteolysis	9/896	43/18722	0.000164111354967354	0.00127394501072419	IL1B/TNFRSF1B/TIMP1/TNF/TIMP2/ROCK1/ADAM10/MYH9/ADAM17	9
GO:0001562	response to protozoan	7/896	26/18722	0.000165931368391257	0.00128042885312007	CLEC7A/SLC11A1/LYST/GBP2/GBP4/MYD88/IRF8	7
GO:0032515	negative regulation of phosphoprotein phosphatase activity	7/896	26/18722	0.000165931368391257	0.00128042885312007	GNAI2/NCKAP1L/TNF/FKBP1A/PPP1R15A/ROCK1/BOD1L1	7
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	7/896	26/18722	0.000165931368391257	0.00128042885312007	NFKBIA/TNFAIP3/TLR4/BIRC3/HSPA1A/CYLD/BIRC2	7
GO:0045672	positive regulation of osteoclast differentiation	7/896	26/18722	0.000165931368391257	0.00128042885312007	TYROBP/FOS/CCR1/NOTCH2/TNF/KLF10/CREB1	7
GO:0090130	tissue migration	34/896	365/18722	0.000168908197055594	0.00130067381384071	TMSB4X/ZEB2/KLF4/RHOB/PTGS2/CYP1B1/NR4A1/MEF2C/GLIPR2/GPX1/GRN/CTSH/TGFB1/HBEGF/TNF/RHOA/MAP3K3/PTK2B/GLUL/PKN1/SP100/RRAS/ROCK1/PTEN/PFN1/HIF1A/PRCP/HMOX1/TGFBR2/CORO1C/MYH9/SP1/ADAM17/CIB1	34
GO:0006970	response to osmotic stress	13/896	84/18722	0.000169305166692975	0.00130067381384071	TSPO/TSC22D3/PTGS2/RCSD1/TNF/AQP9/PTK2B/ZFP36L1/PKN1/HNMT/MICU1/CAB39/DDX3X	13
GO:0098586	cellular response to virus	13/896	84/18722	0.000169305166692975	0.00130067381384071	POU2F2/USP15/LGALS9/OAS1/BIRC3/IRF7/HIF1A/IFIH1/ADAR/SEC14L1/DDX3X/NFKB1/BIRC2	13
GO:0046683	response to organophosphorus	17/896	131/18722	0.000172147748916395	0.0013205611240622	FOS/DUSP1/FOSB/CASP1/PTGS2/STAT1/SLC8A1/PTAFR/AQP9/JUN/PTK2B/ZFP36L1/AHR/RAP1A/PTEN/RAP1B/BIRC2	17
GO:0030282	bone mineralization	16/896	119/18722	0.000174807408320175	0.00133898870496794	SRGN/CCL3/FGR/ISG15/SNX10/PTGS2/MEF2C/CCR1/TGFB1/SLC8A1/ALOX5/PTK2B/KLF10/HIF1A/BMP2K/NBR1	16
GO:0007346	regulation of mitotic cell cycle	40/896	457/18722	0.00017880977572335	0.00136763182873109	AIF1/IL1B/DUSP1/ZFP36L2/KLF4/BTG2/PTPN6/IQGAP1/TGFB1/BID/TNF/BCL6/ZFP36L1/EIF4EBP1/PSME2/TIMP2/PSME1/BTG1/TAOK3/CDKN1A/CDC42/KMT2E/SDCBP/PTEN/CYLD/RB1/ATM/NABP1/HNRNPU/PHIP/FOXN3/TAOK1/WAC/LSM10/ADAM17/DDX3X/NUP62/CTDSP1/ZNF207/DYNC1LI1	40
GO:1990845	adaptive thermogenesis	19/896	157/18722	0.000186534855799041	0.00142018209507566	CD36/PLAC8/CEBPB/JAK2/UCP2/SYK/CCR2/SORL1/CXCR4/STAT6/TLR4/ALDH1A1/ACSL1/KDM6B/RB1/DECR1/LNPEP/HNRNPU/ADAM17	19
GO:0002281	macrophage activation involved in immune response	6/896	19/18722	0.000187318768933263	0.00142018209507566	TYROBP/CX3CR1/GRN/SYK/IFI35/NMI	6
GO:0002902	regulation of B cell apoptotic process	6/896	19/18722	0.000187318768933263	0.00142018209507566	CD74/LYN/BCL6/BTK/PTEN/IRS2	6
GO:0032695	negative regulation of interleukin-12 production	6/896	19/18722	0.000187318768933263	0.00142018209507566	ARRB2/IRAK3/LILRB1/TLR8/LILRA5/NFKB1	6
GO:0033194	response to hydroperoxide	6/896	19/18722	0.000187318768933263	0.00142018209507566	AIF1/CD36/GPX1/JAK2/MGST1/SP1	6
GO:0044546	NLRP3 inflammasome complex assembly	6/896	19/18722	0.000187318768933263	0.00142018209507566	CD36/GBP5/MYD88/TLR4/CARD8/DDX3X	6
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	13/896	85/18722	0.000191263269156119	0.0014479770929854	LYN/SOCS3/JAK2/CSF1R/TNF/IL6R/PARP9/FYN/SH2B3/HCLS1/PARP14/TNFRSF1A/PTPN2	13
GO:0048821	erythrocyte development	8/896	35/18722	0.000198016872790094	0.0014952863285349	KLF2/NCKAP1L/SH2B3/BCL6/G6PD/PTBP3/ARID4A/ZBTB7A	8
GO:0043524	negative regulation of neuron apoptotic process	18/896	145/18722	0.000198087344810718	0.0014952863285349	SOD2/CORO1A/C5AR1/BTG2/ARRB2/NAIP/MEF2C/CEBPB/NR4A2/JAK2/CX3CR1/PPT1/GRN/RHOA/FYN/PTK2B/HIF1A/HMOX1	18
GO:0001885	endothelial cell development	11/896	64/18722	0.000205757881759678	0.00154645483097122	IL1B/MSN/PECAM1/GPX1/MYADM/TNF/MYD88/RAP1A/TNFRSF1A/ROCK1/RAP1B	11
GO:0030837	negative regulation of actin filament polymerization	11/896	64/18722	0.000205757881759678	0.00154645483097122	TMSB4X/TMSB10/MYADM/CAPG/CAPZA1/MTPN/CAPZA2/TWF2/PFN1/FLII/SSH2	11
GO:1903409	reactive oxygen species biosynthetic process	11/896	64/18722	0.000205757881759678	0.00154645483097122	CYBA/NCF1/SOD2/CD36/ALOX5/RHOA/TLR4/RAB27A/FYN/STAT3/CFLAR	11
GO:0070167	regulation of biomineral tissue development	14/896	97/18722	0.000206330910976987	0.00154852390763537	SRGN/CCL3/ISG15/MEF2C/CEBPB/CCR1/TGFB1/SLC8A1/ALOX5/PTK2B/ROCK1/HIF1A/BMP2K/NBR1	14
GO:0009743	response to carbohydrate	26/896	253/18722	0.000210651011063904	0.00157653309133405	CYBA/TXNIP/SOD2/LGALS1/NAMPT/CLEC7A/EGR1/LYN/HLA-DRB1/PTGS2/UCP2/PRKCB/SLC8A1/RHOA/PTK2B/ZFP36L1/GLUL/NADK/RAP1A/PRKACA/PTEN/HIF1A/RAP1B/TGFBR2/IRS2/PPP3CA	26
GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	10/896	54/18722	0.000210669197938313	0.00157653309133405	FOS/SPI1/EGR1/KLF4/TGFB1/TNF/JUN/STAT3/HIF1A/NR3C1	10
GO:0007179	transforming growth factor beta receptor signaling pathway	22/896	198/18722	0.000211345854014583	0.00157932440622104	FOS/ZEB2/SPI1/ARRB2/USP15/ZYX/TGFB1/C20orf27/JUN/HSPA1A/FKBP1A/SKIL/STAT3/SDCBP/ZBTB7A/TGFBR2/DUSP22/ADAM17/CREBBP/EP300/FAM89B/CREB1	22
GO:0038127	ERBB signaling pathway	16/896	121/18722	0.00021263542611346	0.00158668127864577	NCF1/PLAUR/IQGAP1/TGFB1/HBEGF/CCDC88A/RASSF2/PTK2B/PTPN18/SHKBP1/GRB2/MAPK1/PTPN2/ADAM17/MVP/NUP62	16
GO:0050890	cognition	29/896	296/18722	0.000213641358622499	0.00159190359053814	FOS/HLA-DRA/B2M/C5AR1/BTG2/PTGS2/LILRB2/ACTR2/MEF2C/CEBPB/CX3CR1/PPT1/TLR2/TNF/NRGN/FYN/JUN/PICALM/SGK1/PTEN/HIF1A/MAPK1/NIPBL/PIAS1/PJA2/NQO2/PRNP/EP300/CREB1	29
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	5/896	13/18722	0.000231568169916601	0.0017132091774342	CARD16/TNFAIP3/LILRA2/TRIB1/CARD8	5
GO:0034135	regulation of toll-like receptor 2 signaling pathway	5/896	13/18722	0.000231568169916601	0.0017132091774342	CYBA/LYN/TNFAIP3/TLR1/PJA2	5
GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway	5/896	13/18722	0.000231568169916601	0.0017132091774342	TNFAIP3/TLR4/BIRC3/HSPA1A/BIRC2	5
GO:0071801	regulation of podosome assembly	5/896	13/18722	0.000231568169916601	0.0017132091774342	LCP1/MSN/HCK/TNF/RHOA	5
GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	5/896	13/18722	0.000231568169916601	0.0017132091774342	STK4/SKIL/PTEN/ATF3/PEA15	5
GO:0035305	negative regulation of dephosphorylation	9/896	45/18722	0.000236688226176324	0.00174860151185094	GNAI2/NCKAP1L/TNF/FKBP1A/PPP1R15A/CHP1/ROCK1/YWHAB/BOD1L1	9
GO:0045453	bone resorption	11/896	65/18722	0.000237118346928088	0.00174929435797586	SNX10/TNFAIP3/RAC2/TPP1/SYK/CSF1R/CSK/TCIRG1/INPP5D/PTK2B/PDK4	11
GO:0010923	negative regulation of phosphatase activity	8/896	36/18722	0.000244016429361114	0.0017925557190779	GNAI2/NCKAP1L/TNF/FKBP1A/PPP1R15A/CHP1/ROCK1/BOD1L1	8
GO:0060338	regulation of type I interferon-mediated signaling pathway	8/896	36/18722	0.000244016429361114	0.0017925557190779	SAMHD1/ISG15/PTPN6/STAT2/OAS1/IRF7/ADAR/PTPN2	8
GO:0071402	cellular response to lipoprotein particle stimulus	8/896	36/18722	0.000244016429361114	0.0017925557190779	FCER1G/ITGB2/CD36/CD68/SYK/MYD88/TLR4/ADAM17	8
GO:0032720	negative regulation of tumor necrosis factor production	12/896	76/18722	0.000246272254697004	0.00180634765898819	TSPO/TNFAIP3/ARRB2/IRAK3/PTPN6/LILRB1/LGALS9/CLEC4A/TLR4/CD33/SIRPA/DICER1	12
GO:1902991	regulation of amyloid precursor protein catabolic process	10/896	55/18722	0.000246588509494638	0.00180634765898819	LYN/SORL1/TNF/FKBP1A/IFNGR1/PICALM/RTN3/ROCK1/SP1/PRNP	10
GO:0014074	response to purine-containing compound	18/896	148/18722	0.000256303823747304	0.00187072981449821	FOS/DUSP1/FOSB/CASP1/PTGS2/STAT1/SLC8A1/PTAFR/AQP9/JUN/PTK2B/ZFP36L1/AHR/RAP1A/PTEN/RAP1B/XRN1/BIRC2	18
GO:0110149	regulation of biomineralization	14/896	99/18722	0.000256649451620093	0.00187072981449821	SRGN/CCL3/ISG15/MEF2C/CEBPB/CCR1/TGFB1/SLC8A1/ALOX5/PTK2B/ROCK1/HIF1A/BMP2K/NBR1	14
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	6/896	20/18722	0.000256816206028018	0.00187072981449821	SAMHD1/ISG15/STAT2/OAS1/ADAR/PTPN2	6
GO:0140632	inflammasome complex assembly	6/896	20/18722	0.000256816206028018	0.00187072981449821	CD36/GBP5/MYD88/TLR4/CARD8/DDX3X	6
GO:0036294	cellular response to decreased oxygen levels	19/896	161/18722	0.000258946961898336	0.00188098205144308	CYBB/CARD16/NAMPT/EGR1/PTGS2/BACH1/SLC8A1/ZFP36L1/EIF4EBP1/MALAT1/BNIP3L/CFLAR/PTEN/HIF1A/PGK1/GNB1/HMOX1/MDM4/TMBIM6	19
GO:0061572	actin filament bundle organization	19/896	161/18722	0.000258946961898336	0.00188098205144308	AIF1/LCP1/PLEK/FLNA/MARCKS/WAS/ZYX/CCDC88A/RHOA/PHACTR1/GPR65/PTK2B/ARAP1/SHTN1/PAK1/PAK2/CDC42/ROCK1/PFN1	19
GO:0003158	endothelium development	17/896	136/18722	0.000271404679248052	0.00196872487694437	IL1B/MSN/RHOB/PECAM1/GPX1/MYADM/CXCR4/TNF/MYD88/RHOA/ITGAX/BTG1/RAP1A/KDM6B/TNFRSF1A/ROCK1/RAP1B	17
GO:0007260	tyrosine phosphorylation of STAT protein	13/896	88/18722	0.000272381349390373	0.00197031348842744	LYN/SOCS3/JAK2/CSF1R/TNF/IL6R/PARP9/FYN/SH2B3/HCLS1/PARP14/TNFRSF1A/PTPN2	13
GO:0070098	chemokine-mediated signaling pathway	13/896	88/18722	0.000272381349390373	0.00197031348842744	CCL3L3/CCL3/CXCL8/CX3CR1/CCR1/CCR2/CXCR4/CCL4/SH2B3/PTK2B/HIF1A/WNK1/CIB1	13
GO:0002313	mature B cell differentiation involved in immune response	7/896	28/18722	0.000274685163879807	0.00197053453426052	LGALS1/SPI1/NOTCH2/LFNG/DOCK11/IRF8/PTK2B	7
GO:0010575	positive regulation of vascular endothelial growth factor production	7/896	28/18722	0.000274685163879807	0.00197053453426052	IL1B/C5AR1/PTGS2/CYP1B1/TGFB1/SULF2/HIF1A	7
GO:0032607	interferon-alpha production	7/896	28/18722	0.000274685163879807	0.00197053453426052	STAT1/TLR8/TLR4/IRF7/IFIH1/NMI/DDX3X	7
GO:0032647	regulation of interferon-alpha production	7/896	28/18722	0.000274685163879807	0.00197053453426052	STAT1/TLR8/TLR4/IRF7/IFIH1/NMI/DDX3X	7
GO:0034123	positive regulation of toll-like receptor signaling pathway	7/896	28/18722	0.000274685163879807	0.00197053453426052	CYBA/TLR2/TLR1/IFI35/PJA2/DDX3X/NINJ1	7
GO:1990776	response to angiotensin	7/896	28/18722	0.000274685163879807	0.00197053453426052	CYBB/CYBA/PTGS2/AGTRAP/IQGAP1/ROCK1/NFKB1	7
GO:0052126	movement in host environment	20/896	175/18722	0.00027761767275948	0.00198882853446564	FCN1/CD74/IFITM3/LGALS1/HLA-DRB1/CXCL8/IFITM2/LGALS9/TRIM22/CD4/CD86/PLSCR1/CXCR4/SELPLG/TNFRSF14/CTSB/HSPA1A/TRIM38/ITGA5/DYNLT1	20
GO:0140056	organelle localization by membrane tethering	12/896	77/18722	0.000279242276354581	0.00199771537733174	VMP1/STXBP2/PLEK/STX11/STX10/RALB/RAB8B/CTBP2/RAB10/STX7/STX12/BLOC1S6	12
GO:0019439	aromatic compound catabolic process	40/896	467/18722	0.000279643513787208	0.00199783779561438	TYMP/ZFP36/APOBEC3A/VIM/SAMHD1/ZFP36L2/TNFRSF1B/SLC11A1/BTG2/PABPC1/DPYD/RNASET2/BLVRB/CDA/RNASE6/OAS2/MYD88/UPP1/ENTPD1/KYNU/ZFP36L1/HSPA1A/NUDT16/BLVRA/DDX5/ROCK1/MGAT1/HNMT/NUDT3/ATM/HMOX1/TET2/YBX1/HNRNPU/DICER1/XRN2/CELF1/RNH1/XRN1/SMG1	40
GO:0032388	positive regulation of intracellular transport	22/896	202/18722	0.000280929037753753	0.00200426875906347	IL1B/ITGB2/MSN/FLNA/PTGS2/RAC2/JAK2/TGFB1/OAZ1/SORL1/ITGAM/FYN/HCLS1/CHP1/PAK1/CDC42/PRKACA/UBE2D3/TOMM7/MAPK1/PRNP/CIB1	22
GO:2000107	negative regulation of leukocyte apoptotic process	9/896	46/18722	0.000281915939386313	0.0020085545215729	CD74/TSC22D3/LILRB1/IRF7/BCL6/HCLS1/DOCK8/HIF1A/IRS2	9
GO:0010508	positive regulation of autophagy	16/896	124/18722	0.000282644435487721	0.00201099002595299	LRRK2/MTDH/TRIM22/BID/SPTLC2/TRIM38/RALB/C9orf72/BNIP3L/ROCK1/HIF1A/HMOX1/PIP4K2A/CALCOCO2/GNAI3/WAC	16
GO:0043406	positive regulation of MAP kinase activity	15/896	112/18722	0.000288114487166185	0.00204710853517941	IL1B/S100A12/LRRK2/IQGAP1/TGFB1/SYK/CSK/TNF/TLR4/FGD2/PTK2B/AKAP13/PAK1/TAOK3/MAP3K11	15
GO:0006816	calcium ion transport	37/896	422/18722	0.000298171970827505	0.00211445217512367	CYBA/TSPO/PTPRC/VMP1/CORO1A/CCL3/LYN/GNAI2/PTGS2/LILRB2/ARRB2/PTPN6/LILRB1/CCR1/PRKCB/CD4/SLC8A1/KCNE3/CXCR4/LILRA5/LILRA2/RHOA/CD33/FYN/CCL4/PTK2B/FKBP1A/AHNAK/CALM2/G6PD/CD84/PRKACA/DIAPH1/PPP3CA/MICU1/TMBIM6/PRNP	37
GO:0043368	positive T cell selection	8/896	37/18722	0.000298405671321048	0.00211445217512367	PTPRC/CD74/DOCK2/STAT6/IL6R/SPN/STAT3/PTPN2	8
GO:0051056	regulation of small GTPase mediated signal transduction	29/896	302/18722	0.000299679007428975	0.00212058573828313	ARHGDIB/DOCK2/NOTCH2/TAGAP/ARHGAP26/ARHGAP30/LPAR6/FGD2/FGD4/GPR65/BCL6/CYTH4/ARHGAP4/PREX1/FBP1/AKAP13/TIMP2/ARAP1/CYTH1/GABARAP/DOCK8/ARHGEF3/MYO9B/SHOC2/CDC42SE1/DYNLT1/ARHGDIA/NUP62/GNA13	29
GO:0042130	negative regulation of T cell proliferation	11/896	67/18722	0.000312057471844428	0.00220517786829194	HLA-DRB1/LILRB2/CEBPB/PTPN6/LILRB1/LGALS9/CD86/TNFRSF14/SPN/PRKAR1A/PRNP	11
GO:0030500	regulation of bone mineralization	12/896	78/18722	0.00031588359111834	0.00222315366360823	SRGN/CCL3/ISG15/MEF2C/CCR1/TGFB1/SLC8A1/ALOX5/PTK2B/HIF1A/BMP2K/NBR1	12
GO:0070373	negative regulation of ERK1 and ERK2 cascade	12/896	78/18722	0.00031588359111834	0.00222315366360823	DUSP1/PTPRC/DUSP6/LYN/KLF4/GBP1/CSK/TLR4/SIRPA/PTEN/ATF3/PTPN2	12
GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	12/896	78/18722	0.00031588359111834	0.00222315366360823	TSPO/TNFAIP3/ARRB2/IRAK3/PTPN6/LILRB1/LGALS9/CLEC4A/TLR4/CD33/SIRPA/DICER1	12
GO:0002708	positive regulation of lymphocyte mediated immunity	15/896	113/18722	0.000317809749821951	0.00223368717408644	IL1B/HLA-B/PTPRC/HLA-A/HLA-DRA/B2M/HLA-DRB1/HLA-E/HLA-F/TGFB1/NLRP3/TNF/STAT6/BTK/STX7	15
GO:0031589	cell-substrate adhesion	33/896	363/18722	0.000326348285070789	0.00229060382004477	ITGB2/CORO1A/LGALS1/CD44/FLNA/CD36/GBP1/MEGF9/RAC2/ITGA4/JAK2/IQGAP1/ZYX/MYADM/ITGAL/FERMT3/PARVG/MYO1G/BST1/RHOA/BCL6/PREX1/PTK2B/STK4/ITGA5/CDC42/RRAS/ROCK1/PTEN/LIMS1/CORO1C/DUSP22/CIB1	33
GO:0071456	cellular response to hypoxia	18/896	151/18722	0.000328894523829508	0.00230536444533325	CYBB/CARD16/EGR1/PTGS2/BACH1/SLC8A1/ZFP36L1/EIF4EBP1/MALAT1/BNIP3L/CFLAR/PTEN/HIF1A/PGK1/GNB1/HMOX1/MDM4/TMBIM6	18
GO:0030219	megakaryocyte differentiation	10/896	57/18722	0.000333925656460169	0.00233747959522118	MEF2C/PTPN6/FLI1/SH2B3/ZNF385A/PIP4K2A/ABI1/EP300/SP3/CIB1	10
GO:0051767	nitric-oxide synthase biosynthetic process	6/896	21/18722	0.000345069751070029	0.00239613855182272	NAMPT/LRRK2/STAT1/JAK2/TLR2/TLR4	6
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	6/896	21/18722	0.000345069751070029	0.00239613855182272	NAMPT/LRRK2/STAT1/JAK2/TLR2/TLR4	6
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	6/896	21/18722	0.000345069751070029	0.00239613855182272	LAPTM5/CD74/CD36/LILRB1/TLR4/DDX21	6
GO:0071498	cellular response to fluid shear stress	6/896	21/18722	0.000345069751070029	0.00239613855182272	KLF2/KLF4/PTGS2/MEF2C/PTK2B/PLEC	6
GO:0071605	monocyte chemotactic protein-1 production	6/896	21/18722	0.000345069751070029	0.00239613855182272	IL1B/CLEC7A/LGALS9/SYK/OAS1/CD84	6
GO:0071637	regulation of monocyte chemotactic protein-1 production	6/896	21/18722	0.000345069751070029	0.00239613855182272	IL1B/CLEC7A/LGALS9/SYK/OAS1/CD84	6
GO:0032688	negative regulation of interferon-beta production	5/896	14/18722	0.000346061159310811	0.00239662328838286	PYCARD/LILRB1/REL/SIRPA/NMI	5
GO:1902916	positive regulation of protein polyubiquitination	5/896	14/18722	0.000346061159310811	0.00239662328838286	UBE2D1/GABARAP/NMI/DDX3X/BIRC2	5
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	7/896	29/18722	0.00034725528377276	0.00240140885528028	LYN/FGR/HLA-DRB1/HCK/GPX1/SYK/FYN	7
GO:0009266	response to temperature stimulus	20/896	178/18722	0.000347675613925409	0.00240140885528028	FOS/CD14/SOD2/NFKBIA/LYN/PTGS2/ARRB2/PLAC8/UCP2/TFEC/CXCR4/METRNL/HSPA1A/IER5/CDKN1A/PRKACA/ATM/HMOX1/CREBBP/EP300	20
GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	11/896	68/18722	0.000356435604078978	0.0024553928169732	HLA-DRA/NFKBIZ/HLA-DRB1/LGALS9/CD86/NLRP3/STAT6/IL6R/SPN/BCL6/STAT3	11
GO:0042267	natural killer cell mediated cytotoxicity	11/896	68/18722	0.000356435604078978	0.0024553928169732	HLA-B/HLA-A/CORO1A/LYST/HLA-E/ARRB2/PTPN6/LILRB1/LGALS9/HLA-F/RAB27A	11
GO:0009895	negative regulation of catabolic process	30/896	320/18722	0.000358069988486229	0.002463388902271	IL1B/TSPO/ZFP36/CST3/NAMPT/MCL1/TIMP1/LRRK2/SLC11A1/FLNA/PABPC1/IRAK3/IL10RA/SORL1/TNF/MYD88/FYN/FBP1/TIMP2/STAT3/ROCK1/SDCBP/HMOX1/YBX1/MYCBP2/HNRNPU/MDM4/CTSA/WAC/SMG1	30
GO:0097242	amyloid-beta clearance	8/896	38/18722	0.00036229777291583	0.00248918192461721	ITGB2/C5AR1/CD36/TNF/ITGAM/IFNGR1/PICALM/ROCK1	8
GO:0043112	receptor metabolic process	19/896	166/18722	0.000383105586210101	0.00262175283405097	FCER1G/ITGB2/LAPTM5/CD36/ARRB2/CXCL8/LILRB1/TGFB1/SYK/NUMB/SORL1/RIN3/ARAP1/ANKRD13D/DTX3L/PICALM/GRB2/SDCBP/LAMTOR1	19
GO:0060538	skeletal muscle organ development	19/896	166/18722	0.000383105586210101	0.00262175283405097	FOS/VAMP5/EGR1/BTG2/NR4A1/MEF2C/GPCPD1/GPX1/TGFB1/RHOA/FOXN2/DDX5/CFLAR/RB1/ATF3/EEF2/PPP3CA/PLEC/EP300	19
GO:1902904	negative regulation of supramolecular fiber organization	19/896	166/18722	0.000383105586210101	0.00262175283405097	TMSB4X/CORO1A/GMFG/WAS/TMSB10/MYADM/CAPG/PFDN5/ARAP1/CAPZA1/MTPN/CAPZA2/PAK2/TWF2/PFN1/FLII/SSH2/TAOK1/CIB1	19
GO:0032386	regulation of intracellular transport	31/896	337/18722	0.0003995467125254	0.00273067339269988	IL1B/LCP1/ITGB2/LRRK2/MSN/FLNA/CD36/NUP214/PTGS2/RAC2/JAK2/MX2/TGFB1/OAZ1/SORL1/ITGAM/FYN/HCLS1/SP100/CHP1/PAK1/CDC42/PRKACA/BNIP3L/UBE2D3/TOMM7/MAPK1/PPP1R12A/PRNP/NUP62/CIB1	31
GO:0007033	vacuole organization	20/896	180/18722	0.00040253256034229	0.00274746961461975	VMP1/LAPTM5/CORO1A/LRRK2/LYST/PPT1/GRN/TPP1/TCIRG1/ATG16L2/RALB/GABARAP/C9orf72/ATG3/ATP6AP2/PIP4K2A/LAMTOR1/HOOK3/RB1CC1/STX12	20
GO:0002287	alpha-beta T cell activation involved in immune response	11/896	69/18722	0.000405996706028039	0.00276024688634227	HLA-DRA/NFKBIZ/HLA-DRB1/LGALS9/CD86/NLRP3/STAT6/IL6R/SPN/BCL6/STAT3	11
GO:0002293	alpha-beta T cell differentiation involved in immune response	11/896	69/18722	0.000405996706028039	0.00276024688634227	HLA-DRA/NFKBIZ/HLA-DRB1/LGALS9/CD86/NLRP3/STAT6/IL6R/SPN/BCL6/STAT3	11
GO:0034605	cellular response to heat	11/896	69/18722	0.000405996706028039	0.00276024688634227	LYN/PTGS2/TFEC/HSPA1A/IER5/CDKN1A/PRKACA/ATM/HMOX1/CREBBP/EP300	11
GO:0031960	response to corticosteroid	19/896	167/18722	0.000413356965532973	0.00280661824769842	AIF1/CYBB/CYBA/FOS/ZFP36/DUSP1/ZFP36L2/FOSB/PTGS2/IL1RN/TNF/RHOA/PTAFR/ZFP36L1/CDKN1A/CFLAR/HNMT/HNRNPU/NR3C1	19
GO:0009896	positive regulation of catabolic process	41/896	492/18722	0.000415007045846369	0.00281414816877049	IL1B/ZFP36/LAPTM5/ZFP36L2/TNFRSF1B/LRRK2/MSN/BTG2/PABPC1/TNFAIP3/MTDH/TRIM22/OAZ1/SORL1/BID/TNF/PTK2B/ZFP36L1/HSPA1A/FBXL5/SPTLC2/TRIM38/AGTPBP1/RALB/TRIB1/DTX3L/GABARAP/C9orf72/BNIP3L/ROCK1/PTEN/HIF1A/PIAS1/HMOX1/PIP4K2A/CALCOCO2/IRS2/GNAI3/WAC/CELF1/HERPUD1	41
GO:0010975	regulation of neuron projection development	38/896	445/18722	0.000417204464609843	0.00282536513077578	S100A9/RGS2/VIM/LGALS1/B2M/LRRK2/LYN/FLNA/KLF4/ACTR2/IQGAP1/GRN/CTSZ/CCDC88A/PLXNC1/RHOA/FYN/ARHGAP4/PREX1/PTK2B/SETX/CFL1/SKIL/NIN/RAP1A/SHTN1/PAK1/PAK2/TWF2/CFLAR/PTEN/ADAM10/PLXNB2/DBNL/PPP3CA/DYNLT1/EP300/CIB1	38
GO:0018209	peptidyl-serine modification	31/896	338/18722	0.000420332535277315	0.00284284722493799	CD44/LRRK2/PTGS2/ARRB2/PRKCB/TGFB1/SYK/RASSF2/TNF/MAPKAPK3/HCLS1/PKN1/STK4/PAK1/SGK1/RPS6KA3/PAK2/PRKACA/ROCK1/STK38/PTEN/HIPK3/MAPK1/ATM/TGFBR2/CLK1/CAB39/HIPK1/WNK1/SMG1/MORC3	31
GO:0018107	peptidyl-threonine phosphorylation	15/896	116/18722	0.000423205462992024	0.00285856053639158	LRRK2/PRKCB/TGFB1/CALM2/PKN1/PRKAG2/PRKACA/ROCK1/HIPK3/MAPK1/TGFBR2/CLK1/CAB39/HIPK1/WNK1	15
GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	7/896	30/18722	0.000434405121360536	0.00292282152159916	LAPTM5/GBP1/PTPN6/CD300A/DGKZ/PTPN2/PRNP	7
GO:0070168	negative regulation of biomineral tissue development	7/896	30/18722	0.000434405121360536	0.00292282152159916	SRGN/CCL3/CCR1/TGFB1/PTK2B/ROCK1/HIF1A	7
GO:0090314	positive regulation of protein targeting to membrane	7/896	30/18722	0.000434405121360536	0.00292282152159916	ITGB2/ITGAM/FYN/CHP1/PAK1/PRNP/CIB1	7
GO:0002347	response to tumor cell	8/896	39/18722	0.000436894816305153	0.00293577511576628	TXNIP/HLA-A/LAPTM5/SPI1/KLF4/HLA-DRB1/AHR/HNMT	8
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	10/896	59/18722	0.00044565423651222	0.0029907712052904	PTPRC/SOCS3/PTPN6/CD300A/SH2B3/SAMSN1/PARP14/DUSP22/PTPN2/MVP	10
GO:1903533	regulation of protein targeting	12/896	81/18722	0.000451153187476066	0.00302377284544203	ITGB2/LRRK2/RAC2/ITGAM/FYN/CHP1/PAK1/BNIP3L/UBE2D3/TOMM7/PRNP/CIB1	12
GO:0006606	protein import into nucleus	18/896	155/18722	0.000453029106078128	0.00302854033510584	TXNIP/NFKBIA/LRRK2/FLNA/CD36/NUP214/PTGS2/JAK2/TGFB1/SYK/HCLS1/CHP1/CDKN1A/STAT3/MAPK1/NUP50/PPP3CA/NUP62	18
GO:0034614	cellular response to reactive oxygen species	18/896	155/18722	0.000453029106078128	0.00302854033510584	FOS/NCF1/SOD2/KLF2/LRRK2/KLF4/CD36/RHOB/TNFAIP3/CYP1B1/STAT6/GCH1/BTK/JUN/SETX/KDM6B/SIRPA/MAPK1	18
GO:0032727	positive regulation of interferon-alpha production	6/896	22/18722	0.000455389926814669	0.00303651667867063	STAT1/TLR8/TLR4/IRF7/IFIH1/DDX3X	6
GO:0050860	negative regulation of T cell receptor signaling pathway	6/896	22/18722	0.000455389926814669	0.00303651667867063	LAPTM5/GBP1/PTPN6/DGKZ/PTPN2/PRNP	6
GO:0002548	monocyte chemotaxis	11/896	70/18722	0.000461207995256498	0.00306718276980519	AIF1/DUSP1/S100A12/CCL3L3/CCL3/LYN/CX3CR1/CCR1/CCR2/IL6R/CCL4	11
GO:0002762	negative regulation of myeloid leukocyte differentiation	9/896	49/18722	0.000462347873779517	0.00306718276980519	CCL3/LYN/LILRB3/MAFB/LILRB1/TLR4/INPP5D/TRIB1/PTPN2	9
GO:0006953	acute-phase response	9/896	49/18722	0.000462347873779517	0.00306718276980519	IL1B/SERPINA1/PTGS2/CEBPB/PLSCR1/TNF/IL6R/CD163/STAT3	9
GO:0050832	defense response to fungus	9/896	49/18722	0.000462347873779517	0.00306718276980519	S100A9/S100A8/S100A12/COTL1/SPI1/CLEC7A/CLEC4E/USP15/CX3CR1	9
GO:1901361	organic cyclic compound catabolic process	41/896	495/18722	0.000469206717030072	0.00310871864366039	TYMP/ZFP36/APOBEC3A/VIM/SAMHD1/ZFP36L2/TNFRSF1B/SLC11A1/BTG2/PABPC1/DPYD/RNASET2/HSD17B11/BLVRB/CDA/RNASE6/OAS2/MYD88/UPP1/ENTPD1/KYNU/ZFP36L1/HSPA1A/NUDT16/BLVRA/DDX5/ROCK1/MGAT1/HNMT/NUDT3/ATM/HMOX1/TET2/YBX1/HNRNPU/DICER1/XRN2/CELF1/RNH1/XRN1/SMG1	41
GO:0031032	actomyosin structure organization	21/896	196/18722	0.000476794211035654	0.00315497034554254	WAS/ZYX/CCDC88A/RHOA/PHACTR1/GPR65/CNN2/PTK2B/AKAP13/ARAP1/MEF2A/PAK1/PAK2/CDC42/PRKAR1A/CFLAR/ROCK1/PFN1/FLII/MYH9/PLEC	21
GO:0031214	biomineral tissue development	19/896	169/18722	0.000480129942197841	0.00317300613643072	SRGN/CCL3/FGR/ISG15/SNX10/PTGS2/MEF2C/CEBPB/CCR1/TGFB1/SLC8A1/TCIRG1/ALOX5/PTK2B/ROCK1/KLF10/HIF1A/BMP2K/NBR1	19
GO:0002730	regulation of dendritic cell cytokine production	5/896	15/18722	0.000498717254502779	0.00328748851795812	CLEC7A/BST2/SCIMP/TLR4/DDX21	5
GO:0006098	pentose-phosphate shunt	5/896	15/18722	0.000498717254502779	0.00328748851795812	TKT/G6PD/PGLS/PGD/TALDO1	5
GO:0051101	regulation of DNA binding	15/896	118/18722	0.000509011515809874	0.00335109986547741	TMSB4X/NFKBIA/KLF4/IFI16/PLAUR/JAK2/TGFB1/JUN/CALM2/SP100/RB1/ZBTB7A/HMOX1/TAF10/EP300	15
GO:0001894	tissue homeostasis	26/896	268/18722	0.000515618106165439	0.00339030312284001	LYZ/CORO1A/B2M/ACTB/SNX10/PTGS2/TNFAIP3/RAC2/PECAM1/TPP1/CTSH/SYK/CCR2/CSF1R/CSK/OAS1/TCIRG1/TLR4/MBP/ALDH1A1/INPP5D/PTK2B/PDK4/LIPA/RB1/DRAM2	26
GO:0002228	natural killer cell mediated immunity	11/896	71/18722	0.000522564890228036	0.0034258461224538	HLA-B/HLA-A/CORO1A/LYST/HLA-E/ARRB2/PTPN6/LILRB1/LGALS9/HLA-F/RAB27A	11
GO:0150077	regulation of neuroinflammatory response	8/896	40/18722	0.000523488780566455	0.0034258461224538	IL1B/PTPRC/TNFRSF1B/CCL3/LRRK2/PTGS2/GRN/TNF	8
GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	8/896	40/18722	0.000523488780566455	0.0034258461224538	ITGB2/KLF4/ITGA4/CCR2/TNF/ALOX5/RHOA/PTAFR	8
GO:0035821	modulation of process of other organism	14/896	106/18722	0.000524188477226525	0.0034258461224538	S100A9/MPEG1/CCL3/CLEC7A/CX3CR1/CD4/SYK/CCL4/JUN/CFL1/CHD1/RXRA/SP1/EP300	14
GO:0019080	viral gene expression	13/896	94/18722	0.000524975843029356	0.0034258461224538	ZFP36/IFITM3/CCL3/PARP9/CCL4/JUN/CHD1/MGAT1/PCBP2/SP1/SPCS3/EP300/USF2	13
GO:0032091	negative regulation of protein binding	13/896	94/18722	0.000524975843029356	0.0034258461224538	CARD16/B2M/LRRK2/IFIT2/ACTB/ARRB2/ITGA4/CTSZ/SORL1/RALB/CDKN1A/ROCK1/TMBIM6	13
GO:0007034	vacuolar transport	18/896	157/18722	0.000529018005244905	0.00344358278507979	LAPTM5/LRRK2/LYST/RHOB/PSAP/GRN/VPS13C/SORL1/HSPA1A/DTX3L/C9orf72/ATP6V0D1/NCOA4/M6PR/TMEM50A/CHMP1B/HOOK3/LAMP2	18
GO:0051017	actin filament bundle assembly	18/896	157/18722	0.000529018005244905	0.00344358278507979	AIF1/LCP1/PLEK/FLNA/MARCKS/WAS/ZYX/CCDC88A/RHOA/PHACTR1/GPR65/PTK2B/ARAP1/PAK1/PAK2/CDC42/ROCK1/PFN1	18
GO:0106106	cold-induced thermogenesis	17/896	144/18722	0.000533312130474982	0.0034628669046197	CD36/PLAC8/CEBPB/JAK2/UCP2/SYK/CCR2/CXCR4/STAT6/TLR4/ALDH1A1/ACSL1/KDM6B/RB1/DECR1/LNPEP/ADAM17	17
GO:0120161	regulation of cold-induced thermogenesis	17/896	144/18722	0.000533312130474982	0.0034628669046197	CD36/PLAC8/CEBPB/JAK2/UCP2/SYK/CCR2/CXCR4/STAT6/TLR4/ALDH1A1/ACSL1/KDM6B/RB1/DECR1/LNPEP/ADAM17	17
GO:0110150	negative regulation of biomineralization	7/896	31/18722	0.000538161311079074	0.00348999623307015	SRGN/CCL3/CCR1/TGFB1/PTK2B/ROCK1/HIF1A	7
GO:0019083	viral transcription	9/896	50/18722	0.000540235650364627	0.00349908545148994	ZFP36/IFITM3/CCL3/CCL4/JUN/CHD1/SP1/EP300/USF2	9
GO:0110148	biomineralization	19/896	171/18722	0.000556049208349069	0.00359702976694466	SRGN/CCL3/FGR/ISG15/SNX10/PTGS2/MEF2C/CEBPB/CCR1/TGFB1/SLC8A1/TCIRG1/ALOX5/PTK2B/ROCK1/KLF10/HIF1A/BMP2K/NBR1	19
GO:0007611	learning or memory	25/896	255/18722	0.000561179935752828	0.00362263383829867	FOS/B2M/BTG2/PTGS2/LILRB2/ACTR2/MEF2C/CEBPB/CX3CR1/PPT1/TLR2/NRGN/FYN/JUN/PICALM/SGK1/PTEN/HIF1A/MAPK1/PIAS1/PJA2/NQO2/PRNP/EP300/CREB1	25
GO:2000146	negative regulation of cell motility	32/896	359/18722	0.000561400283343343	0.00362263383829867	AIF1/DUSP1/CD74/ARHGDIB/TIMP1/KLF4/RHOB/BST2/CYP1B1/WAS/MEF2C/CX3CR1/TGFB1/TNF/RHOA/RIN3/MCTP1/CD300A/CNN2/ARHGAP4/OSBPL8/TRIB1/SP100/STAT3/RRAS/PTEN/HMOX1/CORO1C/DUSP22/RAP2B/ARHGDIA/GNA13	32
GO:0030336	negative regulation of cell migration	31/896	344/18722	0.000566358706099777	0.00365010115294293	AIF1/DUSP1/CD74/ARHGDIB/TIMP1/KLF4/RHOB/BST2/CYP1B1/MEF2C/CX3CR1/TGFB1/TNF/RHOA/RIN3/MCTP1/CD300A/CNN2/ARHGAP4/OSBPL8/TRIB1/SP100/STAT3/RRAS/PTEN/HMOX1/CORO1C/DUSP22/RAP2B/ARHGDIA/GNA13	31
GO:0043433	negative regulation of DNA-binding transcription factor activity	20/896	185/18722	0.000573773988804483	0.00369331499476747	TMSB4X/PYCARD/NFKBIA/SPI1/FLNA/KLF4/TNFAIP3/ARRB2/CYP1B1/IRAK3/NLRP3/TRIB1/SP100/CHP1/CYLD/RB1/CARD8/COMMD6/HMOX1/PRNP	20
GO:0043903	regulation of biological process involved in symbiotic interaction	11/896	72/18722	0.000590591593248895	0.00379686882136898	FCN1/CD74/IFITM3/LGALS1/HLA-DRB1/CXCL8/IFITM2/LGALS9/TRIM22/CD4/TRIM38	11
GO:0042176	regulation of protein catabolic process	34/896	391/18722	0.000597191107001999	0.00383342391908347	IL1B/CST3/LAPTM5/TNFRSF1B/TIMP1/LRRK2/MSN/FLNA/TNFAIP3/IRAK3/GPX1/OAZ1/SORL1/TNF/FYN/PTK2B/HSPA1A/FBXL5/PSME2/AGTPBP1/TIMP2/TRIB1/PSME1/GABARAP/PRKACA/ROCK1/SDCBP/PTEN/PIAS1/MYCBP2/MDM4/CTSA/WAC/HERPUD1	34
GO:1901136	carbohydrate derivative catabolic process	19/896	172/18722	0.000597751739737877	0.00383342391908347	TYMP/APOBEC3A/CST3/SAMHD1/CD44/DPYD/AOAH/TGFB1/CDA/UPP1/ALDH1A1/NUDT16/NAGK/MGAT1/GNS/NUDT3/IDS/CTBS/NAGA	19
GO:0051170	import into nucleus	18/896	159/18722	0.000615754717057656	0.00394401512736068	TXNIP/NFKBIA/LRRK2/FLNA/CD36/NUP214/PTGS2/JAK2/TGFB1/SYK/HCLS1/CHP1/CDKN1A/STAT3/MAPK1/NUP50/PPP3CA/NUP62	18
GO:0045216	cell-cell junction organization	21/896	200/18722	0.000623087087313774	0.00398357016991974	IL1B/FLNA/ACTB/MTDH/PECAM1/TGFB1/NUMB/CSF1R/CSK/TNF/GPBAR1/RHOA/TLN1/PAK2/CDC42/PRKACA/ROCK1/LIMS1/ADAM10/HIPK1/PLEC	21
GO:1902622	regulation of neutrophil migration	8/896	41/18722	0.000623462049281805	0.00398357016991974	CD74/C5AR1/CXCL8/RAC2/NCKAP1L/BST1/MYD88/RHOG	8
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	9/896	51/18722	0.00062855442832642	0.00401117985487817	HLA-DRA/NFKBIZ/HLA-DRB1/CD83/LGALS9/NCKAP1L/CD86/NLRP3/BCL6	9
GO:0007173	epidermal growth factor receptor signaling pathway	14/896	108/18722	0.000634452817735079	0.00404385919735312	NCF1/PLAUR/IQGAP1/TGFB1/HBEGF/CCDC88A/RASSF2/PTK2B/SHKBP1/GRB2/PTPN2/ADAM17/MVP/NUP62	14
GO:0010639	negative regulation of organelle organization	31/896	347/18722	0.000654892674598411	0.00416902913168462	TSPO/TMSB4X/DUSP1/CORO1A/GMFG/LRRK2/LILRB2/ARRB2/WAS/TMSB10/GPX1/MYADM/CAPG/HSPA1A/ARAP1/CAPZA1/MTPN/CAPZA2/PAK2/TWF2/PRKAR1A/PFN1/ATM/FLII/SSH2/HNRNPU/TAOK1/XRN1/ZNF207/DYNC1LI1/CIB1	31
GO:0050850	positive regulation of calcium-mediated signaling	7/896	32/18722	0.000660699641549254	0.00419572507411193	CCL3/CLEC7A/CD4/SYK/TNF/CCL4/CIB1	7
GO:1901889	negative regulation of cell junction assembly	7/896	32/18722	0.000660699641549254	0.00419572507411193	IL1B/TLR2/TNF/ROCK1/PTEN/CORO1C/DUSP22	7
GO:0043500	muscle adaptation	15/896	121/18722	0.000665382017225552	0.00421516671326443	AIF1/IL1B/CYBA/RGS2/TNFRSF1B/KLF4/MEF2A/G6PD/PAK1/MTPN/TNFRSF1A/CFLAR/ROCK1/HMOX1/PPP3CA	15
GO:1904019	epithelial cell apoptotic process	15/896	121/18722	0.000665382017225552	0.00421516671326443	ZFP36/TNFAIP3/ARRB2/ITGA4/JAK2/BID/TNF/ZFP36L1/STK4/CFLAR/RB1/CAST/HMOX1/TGFBR2/HIPK1	15
GO:0010573	vascular endothelial growth factor production	10/896	62/18722	0.000670122088179907	0.00424003039005316	IL1B/C5AR1/PTGS2/CYP1B1/TGFB1/CCR2/SULF2/TNF/IL6R/HIF1A	10
GO:0043087	regulation of GTPase activity	31/896	348/18722	0.000686995554955909	0.00434151139893765	CCL3L3/PYCARD/CCL3/LRRK2/ARRB2/IQGAP1/PLXNC1/FGD2/DOCK11/FGD4/GPR65/CCL4/RASGRP2/BCL6/PREX1/PTK2B/RHOG/RGS10/ARAP1/ADAP2/RAP1A/PICALM/DOCK8/LIMS1/PLXNB2/CCPG1/CORO1C/RABGAP1L/DYNLT1/WNK1/SNX18	31
GO:0002371	dendritic cell cytokine production	5/896	16/18722	0.000696969804005888	0.00438324056908661	CLEC7A/BST2/SCIMP/TLR4/DDX21	5
GO:0006740	NADPH regeneration	5/896	16/18722	0.000696969804005888	0.00438324056908661	TKT/G6PD/PGLS/PGD/TALDO1	5
GO:0009299	mRNA transcription	5/896	16/18722	0.000696969804005888	0.00438324056908661	C5AR1/FLNA/DDX5/STAT3/HIPK3	5
GO:0071361	cellular response to ethanol	5/896	16/18722	0.000696969804005888	0.00438324056908661	CYBB/SOD2/SPI1/PTEN/ADCY7	5
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	13/896	97/18722	0.000712141335189543	0.00447324527091886	IL1B/MCL1/TNFAIP3/GPX1/TNF/FYN/HSPA1A/CFLAR/HMOX1/PHIP/DDX3X/PEA15/RB1CC1	13
GO:0051384	response to glucocorticoid	17/896	148/18722	0.000731052811454918	0.00458649658911583	AIF1/FOS/ZFP36/DUSP1/ZFP36L2/FOSB/PTGS2/IL1RN/TNF/RHOA/PTAFR/ZFP36L1/CDKN1A/CFLAR/HNMT/HNRNPU/NR3C1	17
GO:0032691	negative regulation of interleukin-1 beta production	8/896	42/18722	0.000738287428922553	0.00462630472027253	CARD16/TNFAIP3/ARRB2/CX3CR1/NLRP3/CD33/SERPINB1/CARD8	8
GO:1905475	regulation of protein localization to membrane	19/896	175/18722	0.000739455234251547	0.00462804653831805	ITGB2/ACTB/GBP1/TGFB1/NUMB/CSK/TNF/ITGAM/FYN/RHOG/CHP1/RAP1A/PICALM/RHOQ/PAK1/ADAM10/PRNP/STX7/CIB1	19
GO:0043302	positive regulation of leukocyte degranulation	6/896	24/18722	0.000756835543542558	0.00470367296809265	ITGB2/FGR/HLA-F/SYK/ITGAM/PTAFR	6
GO:0051043	regulation of membrane protein ectodomain proteolysis	6/896	24/18722	0.000756835543542558	0.00470367296809265	IL1B/TNFRSF1B/TIMP1/TNF/TIMP2/ROCK1	6
GO:0060149	negative regulation of posttranscriptional gene silencing	6/896	24/18722	0.000756835543542558	0.00470367296809265	NEAT1/TGFB1/TNF/STAT3/ADAR/PPP3CA	6
GO:0060967	negative regulation of gene silencing by RNA	6/896	24/18722	0.000756835543542558	0.00470367296809265	NEAT1/TGFB1/TNF/STAT3/ADAR/PPP3CA	6
GO:1903077	negative regulation of protein localization to plasma membrane	6/896	24/18722	0.000756835543542558	0.00470367296809265	GBP1/TGFB1/NUMB/CSK/PICALM/RHOQ	6
GO:0051701	biological process involved in interaction with host	21/896	203/18722	0.000756964867197376	0.00470367296809265	FCN1/CD74/IFITM3/LGALS1/HLA-DRB1/CXCL8/IFITM2/LGALS9/TRIM22/CD4/CD86/PLSCR1/CXCR4/SELPLG/TNFRSF14/CTSB/HSPA1A/TRIM38/ITGA5/RXRA/DYNLT1	21
GO:0016239	positive regulation of macroautophagy	10/896	63/18722	0.000762979104108324	0.00473538701726419	SPTLC2/RALB/C9orf72/BNIP3L/HIF1A/HMOX1/PIP4K2A/CALCOCO2/GNAI3/WAC	10
GO:0034250	positive regulation of cellular amide metabolic process	18/896	162/18722	0.000768702020940933	0.00475954667965928	VIM/PABPC1/TNF/RHOA/RPS9/PTAFR/PTK2B/SERP1/PPP1R15A/IFNGR1/PICALM/CNBP/EIF2S3/MAPK1/PLXNB2/EEF2/SP1/DDX3X	18
GO:0051494	negative regulation of cytoskeleton organization	18/896	162/18722	0.000768702020940933	0.00475954667965928	TMSB4X/CORO1A/GMFG/WAS/TMSB10/MYADM/CAPG/ARAP1/CAPZA1/MTPN/CAPZA2/PAK2/TWF2/PFN1/FLII/SSH2/TAOK1/CIB1	18
GO:1903829	positive regulation of cellular protein localization	26/896	276/18722	0.000800953418699582	0.00495333975107791	TYROBP/ITGB2/MSN/FLNA/PTGS2/RAC2/JAK2/IQGAP1/TGFB1/SORL1/CCDC88A/TNF/ITGAM/PARP9/FYN/RHOG/HCLS1/DTX3L/CHP1/PAK1/UBE2D3/TOMM7/MAPK1/PRNP/NUP62/CIB1	26
GO:0034110	regulation of homotypic cell-cell adhesion	7/896	33/18722	0.000804342383991506	0.00496249672495827	LGALS1/LYN/PLAUR/JAK2/SYK/SH2B3/JAK1	7
GO:0045648	positive regulation of erythrocyte differentiation	7/896	33/18722	0.000804342383991506	0.00496249672495827	ISG15/STAT1/NCKAP1L/INPP5D/HSPA1A/STAT3/HIF1A	7
GO:0051271	negative regulation of cellular component movement	32/896	367/18722	0.000815542460240854	0.00502563546885389	AIF1/DUSP1/CD74/ARHGDIB/TIMP1/KLF4/RHOB/BST2/CYP1B1/WAS/MEF2C/CX3CR1/TGFB1/TNF/RHOA/RIN3/MCTP1/CD300A/CNN2/ARHGAP4/OSBPL8/TRIB1/SP100/STAT3/RRAS/PTEN/HMOX1/CORO1C/DUSP22/RAP2B/ARHGDIA/GNA13	32
GO:0048662	negative regulation of smooth muscle cell proliferation	11/896	75/18722	0.000840374790361107	0.00517253169783209	AIF1/SOD2/KLF4/TNFAIP3/MEF2C/RHOA/TRIB1/CDKN1A/PTEN/HMOX1/GNA13	11
GO:0010632	regulation of epithelial cell migration	27/896	292/18722	0.000851180842396747	0.00523285054527834	TMSB4X/KLF4/RHOB/PTGS2/MEF2C/GLIPR2/GRN/CTSH/TGFB1/HBEGF/TNF/RHOA/MAP3K3/PTK2B/GLUL/SP100/RRAS/PTEN/PFN1/HIF1A/PRCP/HMOX1/TGFBR2/CORO1C/SP1/ADAM17/CIB1	27
GO:0050821	protein stabilization	20/896	191/18722	0.000859564994715483	0.00527702851172012	TYROBP/FLNA/IFI30/GRN/RASSF2/HSPA1A/STK4/MFSD1/CHP1/GNAQ/PTEN/PFN1/CRTAP/MDM4/EP300/LAMP2/ZNF207/MORC3/STX12/CREB1	20
GO:0048247	lymphocyte chemotaxis	10/896	64/18722	0.000866168219358074	0.00527702851172012	CCL3L3/CCL3/CCR2/CCL4/PTK2B/CKLF/ADAM10/ADAM17/PLEC/WNK1	10
GO:1900076	regulation of cellular response to insulin stimulus	10/896	64/18722	0.000866168219358074	0.00527702851172012	IL1B/GNAI2/SOCS3/PTPRE/PRKCB/SORL1/OSBPL8/PAK1/PIP4K2A/PTPN2	10
GO:0002765	immune response-inhibiting signal transduction	4/896	10/18722	0.00086777008970125	0.00527702851172012	LYN/LILRB2/LILRB1/CD33	4
GO:0070391	response to lipoteichoic acid	4/896	10/18722	0.00086777008970125	0.00527702851172012	CD14/CD36/TLR2/TLR4	4
GO:0071223	cellular response to lipoteichoic acid	4/896	10/18722	0.00086777008970125	0.00527702851172012	CD14/CD36/TLR2/TLR4	4
GO:0071803	positive regulation of podosome assembly	4/896	10/18722	0.00086777008970125	0.00527702851172012	LCP1/MSN/TNF/RHOA	4
GO:0090647	modulation of age-related behavioral decline	4/896	10/18722	0.00086777008970125	0.00527702851172012	B2M/PICALM/BAZ2B/PRNP	4
GO:0014002	astrocyte development	8/896	43/18722	0.000869527674398028	0.00527702851172012	S100A9/S100A8/VIM/C5AR1/GRN/TNF/TLR4/IFNGR1	8
GO:0031952	regulation of protein autophosphorylation	8/896	43/18722	0.000869527674398028	0.00527702851172012	PTPRC/IQGAP1/RASSF2/CALM2/CHP1/RAP2B/MVP/DDX3X	8
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	8/896	43/18722	0.000869527674398028	0.00527702851172012	CD74/PYCARD/CD44/IFI16/CDKN1A/ZNF385A/HIPK1/EP300	8
GO:0002064	epithelial cell development	22/896	220/18722	0.000903612040028262	0.00547748976711771	IL1B/VIM/MSN/FLNA/PECAM1/GPX1/IQGAP1/MYADM/NOTCH2/RILPL2/CXCR4/TNF/MYD88/RAP1A/CDKN1A/TNFRSF1A/ROCK1/FOSL2/HIF1A/RAP1B/ARID4A/PLEC	22
GO:0017038	protein import	21/896	206/18722	0.000915002593178667	0.00554007972889668	TXNIP/NFKBIA/LRRK2/FLNA/CD36/NUP214/PTGS2/JAK2/TGFB1/SYK/HCLS1/RAB8B/CHP1/CDKN1A/STAT3/TOMM7/MAPK1/NUP50/PPP3CA/NUP62/LAMP2	21
GO:0055076	transition metal ion homeostasis	16/896	138/18722	0.000935282206427792	0.00565385365399639	S100A9/S100A8/B2M/SLC11A1/FTL/FTH1/SCO2/FBXL5/PICALM/ATP6V0D1/ATP6V1A/HIF1A/NCOA4/HMOX1/SLC31A2/PRNP	16
GO:0018210	peptidyl-threonine modification	15/896	125/18722	0.000935967697767909	0.00565385365399639	LRRK2/PRKCB/TGFB1/CALM2/PKN1/PRKAG2/PRKACA/ROCK1/HIPK3/MAPK1/TGFBR2/CLK1/CAB39/HIPK1/WNK1	15
GO:0140029	exocytic process	11/896	76/18722	0.000940915219473497	0.0056771462372177	STXBP2/PLEK/LYN/SYK/STX11/BTK/RALB/RAB8B/CTBP2/RAB10/BLOC1S6	11
GO:0051604	protein maturation	27/896	294/18722	0.000943065733580637	0.0056835282506986	CTSS/SRGN/PYCARD/CARD16/LRRK2/IFI16/CASP1/CTSH/CTSZ/SORL1/FKBP1A/CAPN2/FAM111A/PRKACA/TSPAN14/CAST/PGK1/ADAM10/CARD8/ATP6AP2/MYH9/ADAM17/SEC11A/PRNP/SPCS3/CREBBP/EP300	27
GO:0045591	positive regulation of regulatory T cell differentiation	5/896	17/18722	0.000948715708663778	0.00569777182535833	HLA-DRA/HLA-DRB1/LILRB2/LGALS9/BCL6	5
GO:0072673	lamellipodium morphogenesis	5/896	17/18722	0.000948715708663778	0.00569777182535833	CD44/PLEKHO1/CORO1C/ABI1/SNX2	5
GO:0090713	immunological memory process	5/896	17/18722	0.000948715708663778	0.00569777182535833	FGL2/HLA-DRA/HLA-DRB1/TNFRSF14/BCL6	5
GO:0035902	response to immobilization stress	6/896	25/18722	0.00095590523022313	0.00572772246819182	FOS/SOD2/ACTR2/SLC8A1/PTK2B/HNMT	6
GO:1905048	regulation of metallopeptidase activity	6/896	25/18722	0.00095590523022313	0.00572772246819182	TIMP1/SORL1/MBP/TIMP2/PICALM/STAT3	6
GO:0010810	regulation of cell-substrate adhesion	22/896	221/18722	0.000959411660798307	0.00574211743131415	LGALS1/FLNA/CD36/GBP1/RAC2/JAK2/IQGAP1/MYADM/BST1/RHOA/BCL6/PREX1/PTK2B/STK4/CDC42/RRAS/ROCK1/PTEN/LIMS1/CORO1C/DUSP22/CIB1	22
GO:0009144	purine nucleoside triphosphate metabolic process	12/896	88/18722	0.000965188539515896	0.00576832770936808	TMSB4X/SAMHD1/LRRK2/GIMAP7/TGFB1/RHOA/NUDT16/PRKAG2/RHOQ/ATP6V1A/STAT3/GNAI3	12
GO:1902743	regulation of lamellipodium organization	9/896	54/18722	0.00096663504701776	0.00576832770936808	CD44/ACTR2/WAS/RAC2/ACTR3/TWF2/CDC42/BRK1/CORO1C	9
GO:0030851	granulocyte differentiation	7/896	34/18722	0.000971554522862226	0.00576832770936808	EVI2B/SPI1/INPP5D/HCLS1/TRIB1/LBR/SP3	7
GO:0032743	positive regulation of interleukin-2 production	7/896	34/18722	0.000971554522862226	0.00576832770936808	IL1B/PTPRC/CLEC7A/CD83/CD4/CD86/CCR2	7
GO:0044319	wound healing, spreading of cells	7/896	34/18722	0.000971554522862226	0.00576832770936808	CD44/FLNA/HBEGF/RHOA/ITGA5/PTEN/ADAM17	7
GO:0055094	response to lipoprotein particle	7/896	34/18722	0.000971554522862226	0.00576832770936808	FCER1G/ITGB2/CD36/CD68/SYK/MYD88/TLR4	7
GO:0090505	epiboly involved in wound healing	7/896	34/18722	0.000971554522862226	0.00576832770936808	CD44/FLNA/HBEGF/RHOA/ITGA5/PTEN/ADAM17	7
GO:0007565	female pregnancy	20/896	193/18722	0.000978751159772443	0.0058044296259709	IL1B/FOS/RGS2/VMP1/JUNB/NAMPT/FOSB/ARHGDIB/TIMP1/PTGS2/LGALS9/UCP2/CTSB/CAPN2/ADCY7/MAPK1/ACSL4/LNPEP/TGFBR2/SP3	20
GO:0150076	neuroinflammatory response	8/896	44/18722	0.00101883452212353	0.0060283940268083	IL1B/PTPRC/TNFRSF1B/CCL3/LRRK2/PTGS2/GRN/TNF	8
GO:1903573	negative regulation of response to endoplasmic reticulum stress	8/896	44/18722	0.00101883452212353	0.0060283940268083	LRRK2/ALOX5/HSPA1A/PPP1R15A/PPP1R15B/TMBIM6/GRINA/HERPUD1	8
GO:1901654	response to ketone	20/896	194/18722	0.00104348226291506	0.00616323961902767	CYBB/CYBA/FOS/TXNIP/TSPO/DUSP1/KLF2/FOSB/MSN/KLF4/TLR2/TGFB1/PTAFR/AHR/CDKN1A/CFLAR/NCOA4/GNB1/NR3C1/XRN1	20
GO:1904062	regulation of cation transmembrane transport	31/896	357/18722	0.00104399425194451	0.00616323961902767	CTSS/CYBA/TMSB4X/RGS2/VMP1/CORO1A/LYN/FLNA/FXYD5/MEF2C/IFNGR2/PTPN6/CCR2/SLC8A1/KCNE3/TCIRG1/FYN/PTK2B/GLRX/FKBP1A/AHNAK/CALM2/G6PD/CHP1/PRKACA/DIAPH1/PTEN/SLC31A2/CAB39/PRNP/WNK1	31
GO:0007041	lysosomal transport	14/896	114/18722	0.00108994109528603	0.00642719233172635	LAPTM5/LRRK2/LYST/RHOB/PSAP/GRN/SORL1/HSPA1A/DTX3L/C9orf72/NCOA4/M6PR/HOOK3/LAMP2	14
GO:0042093	T-helper cell differentiation	10/896	66/18722	0.0011069906149263	0.00650867666012604	HLA-DRA/NFKBIZ/HLA-DRB1/CD86/NLRP3/STAT6/IL6R/SPN/BCL6/STAT3	10
GO:0046626	regulation of insulin receptor signaling pathway	10/896	66/18722	0.0011069906149263	0.00650867666012604	IL1B/GNAI2/SOCS3/PTPRE/PRKCB/SORL1/OSBPL8/PAK1/PIP4K2A/PTPN2	10
GO:0061098	positive regulation of protein tyrosine kinase activity	9/896	55/18722	0.00110751371740272	0.00650867666012604	NCF1/FCGR1A/HBEGF/CSF1R/LILRA5/PAK2/ABI1/ADAM17/PRNP	9
GO:0010522	regulation of calcium ion transport into cytosol	13/896	102/18722	0.00114786549117853	0.00673820363388207	CYBA/CORO1A/LYN/PTPN6/SLC8A1/FYN/PTK2B/FKBP1A/CALM2/PRKACA/DIAPH1/TMBIM6/PRNP	13
GO:0006739	NADP metabolic process	7/896	35/18722	0.00116493893538025	0.00682302635463142	TKT/G6PD/NADK/PGLS/PGD/TALDO1/ME2	7
GO:0090504	epiboly	7/896	35/18722	0.00116493893538025	0.00682302635463142	CD44/FLNA/HBEGF/RHOA/ITGA5/PTEN/ADAM17	7
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	11/896	78/18722	0.00117191665488323	0.00685617381557672	S100A9/S100A8/LAPTM5/PYCARD/JAK2/CTSH/BID/TNF/APAF1/CFLAR/CARD8	11
GO:0040013	negative regulation of locomotion	33/896	391/18722	0.00118344449743557	0.00691583688894654	AIF1/DUSP1/CD74/ARHGDIB/TIMP1/KLF4/RHOB/BST2/CYP1B1/WAS/MEF2C/CX3CR1/TGFB1/TNF/RHOA/RIN3/MCTP1/CD300A/CNN2/ARHGAP4/OSBPL8/TRIB1/SP100/STAT3/RRAS/PTEN/HMOX1/CORO1C/DUSP22/PTPN2/RAP2B/ARHGDIA/GNA13	33
GO:0030278	regulation of ossification	14/896	115/18722	0.00118763249842659	0.00692658471747843	SRGN/CCL3/ISG15/MEF2C/CCR1/TGFB1/SLC8A1/ALOX5/PTK2B/HIF1A/MAPK1/BMP2K/NIPBL/NBR1	14
GO:0071354	cellular response to interleukin-6	8/896	45/18722	0.00118794723476077	0.00692658471747843	SPI1/JAK2/SELPLG/IL6R/JAK1/STAT3/PTPN2/NFKB1	8
GO:0051016	barbed-end actin filament capping	6/896	26/18722	0.00119289738877269	0.00693213331732599	CAPG/CAPZA1/MTPN/CAPZA2/TWF2/FLII	6
GO:0070102	interleukin-6-mediated signaling pathway	6/896	26/18722	0.00119289738877269	0.00693213331732599	SPI1/JAK2/IL6R/JAK1/STAT3/PTPN2	6
GO:1904376	negative regulation of protein localization to cell periphery	6/896	26/18722	0.00119289738877269	0.00693213331732599	GBP1/TGFB1/NUMB/CSK/PICALM/RHOQ	6
GO:0034655	nucleobase-containing compound catabolic process	34/896	407/18722	0.00119659496662224	0.00694585984531504	TYMP/ZFP36/APOBEC3A/VIM/SAMHD1/ZFP36L2/TNFRSF1B/SLC11A1/BTG2/PABPC1/DPYD/RNASET2/CDA/RNASE6/OAS2/MYD88/UPP1/ENTPD1/ZFP36L1/HSPA1A/NUDT16/DDX5/ROCK1/MGAT1/NUDT3/ATM/YBX1/HNRNPU/DICER1/XRN2/CELF1/RNH1/XRN1/SMG1	34
GO:0060249	anatomical structure homeostasis	28/896	314/18722	0.00120143910706141	0.00696620378575963	LYZ/CORO1A/B2M/ACTB/SNX10/PTGS2/TNFAIP3/RAC2/PECAM1/TPP1/CTSH/SYK/CCR2/CSF1R/CSK/OAS1/TCIRG1/TLR4/MBP/ALDH1A1/INPP5D/PTK2B/PDK4/LIPA/RB1/HIF1A/TAOK1/DRAM2	28
GO:0016485	protein processing	22/896	225/18722	0.00121335281560715	0.00701963069407428	CTSS/SRGN/PYCARD/CARD16/LRRK2/IFI16/CASP1/CTSH/CTSZ/CAPN2/FAM111A/PRKACA/CAST/PGK1/ADAM10/CARD8/ATP6AP2/MYH9/ADAM17/SEC11A/PRNP/SPCS3	22
GO:0050769	positive regulation of neurogenesis	22/896	225/18722	0.00121335281560715	0.00701963069407428	IL1B/TSPO/TNFRSF1B/LYN/ACTR2/CX3CR1/TLR2/TGFB1/NUMB/CXCR4/PLXNC1/TNF/SKIL/NIN/SHTN1/PAK1/TWF2/HIF1A/PLXNB2/DBNL/SPEN/DICER1	22
GO:0035914	skeletal muscle cell differentiation	10/896	67/18722	0.00124645256985294	0.00718418364931467	FOS/EGR1/BTG2/NR4A1/MEF2C/FOXN2/DDX5/RB1/ATF3/EEF2	10
GO:0072665	protein localization to vacuole	10/896	67/18722	0.00124645256985294	0.00718418364931467	LAPTM5/TNFAIP3/GBP1/VPS13C/SORL1/LAMTOR4/MFSD1/NCOA4/M6PR/LAMP2	10
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	10/896	67/18722	0.00124645256985294	0.00718418364931467	HLA-DRA/NFKBIZ/HLA-DRB1/CD83/LGALS9/NCKAP1L/CD86/NLRP3/BCL6/TGFBR2	10
GO:0001503	ossification	34/896	408/18722	0.00124732125270739	0.00718418364931467	VCAN/SRGN/JUNB/CCL3/FGR/ISG15/SNX10/PTGS2/MEF2C/CEBPB/CCR1/TGFB1/SLC8A1/RASSF2/TNF/TCIRG1/ALOX5/RHOA/IL6R/PTK2B/JUND/PRKACA/DDX5/CLIC1/KLF10/HIF1A/MAPK1/BMP2K/NIPBL/ADAR/HNRNPU/DDX21/SP3/NBR1	34
GO:0097709	connective tissue replacement	5/896	18/18722	0.00126224037822884	0.00726207102562852	TIMP1/TGFB1/ROCK1/HIF1A/PPP3CA	5
GO:0031529	ruffle organization	9/896	56/18722	0.00126453817604968	0.00726725199296617	AIF1/PLEK/SNX10/CSF1R/TCIRG1/RHOG/PFN1/DBNL/CORO1C	9
GO:2000045	regulation of G1/S transition of mitotic cell cycle	16/896	142/18722	0.00127066869992221	0.0072944237398404	AIF1/KLF4/PTPN6/BID/PSME2/PSME1/CDKN1A/KMT2E/PTEN/RB1/ATM/WAC/LSM10/ADAM17/DDX3X/CTDSP1	16
GO:0006885	regulation of pH	12/896	91/18722	0.00130112823375585	0.00745624423442253	LRRK2/SLC11A1/DMXL2/PPT1/GRN/TCIRG1/HVCN1/PDK4/CHP1/ATP6V0D1/MAPK1/ATP6AP2	12
GO:0019216	regulation of lipid metabolic process	29/896	331/18722	0.00130172462312164	0.00745624423442253	IL1B/TSPO/CD74/EGR1/LYN/FGR/PTGS2/PSAP/NPC2/TGFB1/SORL1/TNF/LPGAT1/PTK2B/LACTB/CAPN2/PDK4/CHP1/PRKAG2/ELOVL5/CDC42/ASAH1/DGKZ/MBOAT7/PIP4K2A/LAMTOR1/IRS2/NFKB1/CREB1	29
GO:0032272	negative regulation of protein polymerization	11/896	79/18722	0.00130381936682132	0.00746002698221967	TMSB4X/TMSB10/MYADM/CAPG/CAPZA1/MTPN/CAPZA2/TWF2/PFN1/FLII/SSH2	11
GO:0002604	regulation of dendritic cell antigen processing and presentation	4/896	11/18722	0.00131216422979436	0.00746670258113839	FGL2/CD74/SLC11A1/CD68	4
GO:0032493	response to bacterial lipoprotein	4/896	11/18722	0.00131216422979436	0.00746670258113839	CD14/CD36/TLR2/TLR1	4
GO:0046643	regulation of gamma-delta T cell activation	4/896	11/18722	0.00131216422979436	0.00746670258113839	PTPRC/LILRB1/NCKAP1L/SYK	4
GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	4/896	11/18722	0.00131216422979436	0.00746670258113839	LAPTM5/CASP1/HSPA1A/ADAM17	4
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	4/896	11/18722	0.00131216422979436	0.00746670258113839	CD74/TNF/TLR4/MBP	4
GO:0031099	regeneration	20/896	198/18722	0.00134042237378993	0.00761916586456989	LCP1/TSPO/C5AR1/FLNA/KLF4/CEBPB/GPX1/JAK2/GRN/UCP2/SULF2/RAP1A/MTPN/CDKN1A/CFLAR/PTEN/HMOX1/TGFBR2/PPP3CA/NINJ1	20
GO:0030010	establishment of cell polarity	16/896	143/18722	0.00136879747735946	0.0077719603490683	MSN/DOCK2/TCIRG1/RHOA/PTK2B/CYTH1/SHTN1/PAK1/CDC42/DOCK8/ROCK1/RAP1B/MYH9/RAB10/DYNLT1/FAM89B	16
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	7/896	36/18722	0.00138723057476419	0.0078594621125801	NCF1/PLAUR/HBEGF/CCDC88A/SHKBP1/ADAM17/NUP62	7
GO:0090313	regulation of protein targeting to membrane	7/896	36/18722	0.00138723057476419	0.0078594621125801	ITGB2/ITGAM/FYN/CHP1/PAK1/PRNP/CIB1	7
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	10/896	68/18722	0.00139990377084845	0.00791402120889432	LYN/JAK2/CSF1R/TNF/IL6R/PARP9/FYN/HCLS1/PARP14/TNFRSF1A	10
GO:0046686	response to cadmium ion	10/896	68/18722	0.00139990377084845	0.00791402120889432	CYBB/FOS/NCF1/SOD2/B2M/JUN/UBE2D3/MAPK1/HMOX1/PRNP	10
GO:0034205	amyloid-beta formation	9/896	57/18722	0.00143902802347271	0.0081263678068204	SORL1/TNF/IFNGR1/PICALM/RTN3/ROCK1/ADAM10/SP1/PRNP	9
GO:0032703	negative regulation of interleukin-2 production	6/896	27/18722	0.00147234840898957	0.00828753687787311	ZFP36/PTPRC/LAPTM5/TNFAIP3/GBP1/PRNP	6
GO:0036037	CD8-positive, alpha-beta T cell activation	6/896	27/18722	0.00147234840898957	0.00828753687787311	HLA-A/IRF1/HLA-E/LILRB1/CLEC4A/NCKAP1L	6
GO:1902914	regulation of protein polyubiquitination	6/896	27/18722	0.00147234840898957	0.00828753687787311	UBE2D1/GABARAP/NMI/DDX3X/TRIP12/BIRC2	6
GO:0000082	G1/S transition of mitotic cell cycle	21/896	214/18722	0.00148204285295156	0.00833308635481195	AIF1/KLF4/PTPN6/BACH1/BID/EIF4EBP1/PSME2/PSME1/CDKN1A/KMT2E/PTEN/RB1/PIAS1/ATM/PPP3CA/WAC/LSM10/ADAM17/DDX3X/TAF10/CTDSP1	21
GO:0040029	regulation of gene expression, epigenetic	13/896	105/18722	0.00150269622144838	0.0084400896843985	KLF2/SPI1/IFI16/GPX1/KDM1B/XIST/SMCHD1/ARID4A/MBD2/ARID1A/HNRNPU/EP300/EPC1	13
GO:0007204	positive regulation of cytosolic calcium ion concentration	28/896	319/18722	0.00152141820378861	0.00853602597400706	CYBA/PTPRC/CD52/CORO1A/FPR1/CCL3/C5AR1/LYN/CD36/PTPN6/JAK2/CX3CR1/CCR1/CCR2/SLC8A1/CXCR4/LPAR6/FYN/GPR65/PTK2B/FKBP1A/CALM2/PRKACA/DIAPH1/GNB1/TMBIM6/PRNP/GNA13	28
GO:0045446	endothelial cell differentiation	14/896	118/18722	0.00152574575438561	0.00855108153939605	IL1B/MSN/PECAM1/GPX1/MYADM/CXCR4/TNF/MYD88/BTG1/RAP1A/KDM6B/TNFRSF1A/ROCK1/RAP1B	14
GO:0097300	programmed necrotic cell death	8/896	47/18722	0.00159297285202781	0.00890865785311465	CASP1/TNF/BIRC3/CFLAR/CYLD/ASAH1/PYGL/BIRC2	8
GO:1900744	regulation of p38MAPK cascade	8/896	47/18722	0.00159297285202781	0.00890865785311465	IL1B/NCF1/DUSP1/SPI1/GADD45B/MAP3K3/CYLD/PJA2	8
GO:0030641	regulation of cellular pH	11/896	81/18722	0.00160426480905229	0.00896217107613422	LRRK2/SLC11A1/DMXL2/PPT1/GRN/TCIRG1/HVCN1/CHP1/ATP6V0D1/MAPK1/ATP6AP2	11
GO:0030038	contractile actin filament bundle assembly	13/896	106/18722	0.00163947687386648	0.00906946938181641	WAS/ZYX/CCDC88A/RHOA/PHACTR1/GPR65/PTK2B/ARAP1/PAK1/PAK2/CDC42/ROCK1/PFN1	13
GO:0043149	stress fiber assembly	13/896	106/18722	0.00163947687386648	0.00906946938181641	WAS/ZYX/CCDC88A/RHOA/PHACTR1/GPR65/PTK2B/ARAP1/PAK1/PAK2/CDC42/ROCK1/PFN1	13
GO:0002369	T cell cytokine production	7/896	37/18722	0.00164128971890092	0.00906946938181641	IL1B/HLA-A/TNFRSF1B/B2M/HLA-F/NLRP3/CCR2	7
GO:0002724	regulation of T cell cytokine production	7/896	37/18722	0.00164128971890092	0.00906946938181641	IL1B/HLA-A/TNFRSF1B/B2M/HLA-F/NLRP3/CCR2	7
GO:0006904	vesicle docking involved in exocytosis	7/896	37/18722	0.00164128971890092	0.00906946938181641	STXBP2/PLEK/RALB/RAB8B/CTBP2/RAB10/BLOC1S6	7
GO:1902745	positive regulation of lamellipodium organization	7/896	37/18722	0.00164128971890092	0.00906946938181641	ACTR2/RAC2/ACTR3/TWF2/CDC42/BRK1/CORO1C	7
GO:0023061	signal release	37/896	463/18722	0.00164611493326308	0.00906946938181641	IL1B/STXBP2/LRRK2/LYN/HLA-DRB1/NR4A1/MEF2C/RETN/LILRB1/JAK2/PPT1/IL1RN/UCP2/PRKCB/SYK/STX11/TNF/TCIRG1/ALOX5/MCTP1/BTK/SERP1/GLUL/MIDN/CYB5R4/NADK/RAB8B/RAP1A/HIF1A/RAP1B/RAB11FIP1/CTBP2/ACSL4/IRS2/PPP3CA/BLOC1S6/CREB1	37
GO:0002523	leukocyte migration involved in inflammatory response	5/896	19/18722	0.00164614095297725	0.00906946938181641	S100A9/S100A8/NLRP3/ALOX5/NINJ1	5
GO:0030220	platelet formation	5/896	19/18722	0.00164614095297725	0.00906946938181641	MEF2C/PTPN6/MYH9/EP300/CIB1	5
GO:0036344	platelet morphogenesis	5/896	19/18722	0.00164614095297725	0.00906946938181641	MEF2C/PTPN6/MYH9/EP300/CIB1	5
GO:0060216	definitive hemopoiesis	5/896	19/18722	0.00164614095297725	0.00906946938181641	ZFP36L2/LYL1/ADAR/HIPK1/SP3	5
GO:0061760	antifungal innate immune response	5/896	19/18722	0.00164614095297725	0.00906946938181641	SPI1/CLEC7A/CLEC4E/USP15/CX3CR1	5
GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	5/896	19/18722	0.00164614095297725	0.00906946938181641	HLA-A/IRF1/HLA-E/LILRB1/NCKAP1L	5
GO:0002377	immunoglobulin production	21/896	216/18722	0.00166346533780328	0.00915522034065066	PTPRC/SAMHD1/HLA-DRA/HLA-DPA1/B2M/HLA-DPB1/HLA-DRB1/HLA-E/HLA-DQB1/HLA-DMA/HLA-DMB/TGFB1/CD86/TNF/STAT6/GAPT/HLA-DQA1/BCL6/BTK/PKN1/TMBIM6	21
GO:0008637	apoptotic mitochondrial changes	13/896	107/18722	0.00178640283025553	0.00982143881623576	PYCARD/SOD2/TNFSF10/IFIT2/ARRB2/PLAUR/GPX1/BID/JUN/HSPA1A/CHCHD10/ATG3/BNIP3L	13
GO:0032411	positive regulation of transporter activity	14/896	120/18722	0.00179298498491352	0.0098386066762403	CTSS/TMSB4X/VMP1/IFNGR2/CCR2/KCNE3/PTAFR/GLRX/CALM2/CHP1/SGK1/RXRA/WNK1/KMT2A	14
GO:0002675	positive regulation of acute inflammatory response	6/896	28/18722	0.00179898383947405	0.0098386066762403	IL1B/PTGS2/HLA-E/TNF/BTK/ALOX5AP	6
GO:0010818	T cell chemotaxis	6/896	28/18722	0.00179898383947405	0.0098386066762403	CCL3/CCR2/ADAM10/ADAM17/PLEC/WNK1	6
GO:0045589	regulation of regulatory T cell differentiation	6/896	28/18722	0.00179898383947405	0.0098386066762403	HLA-DRA/IRF1/HLA-DRB1/LILRB2/LGALS9/BCL6	6
GO:0045671	negative regulation of osteoclast differentiation	6/896	28/18722	0.00179898383947405	0.0098386066762403	CCL3/LILRB3/MAFB/LILRB1/TLR4/INPP5D	6
GO:0033628	regulation of cell adhesion mediated by integrin	8/896	48/18722	0.00183278215717545	0.010002413430713	LYN/CYP1B1/PTPN6/FERMT3/NCKAP1L/SYK/WNK1/CIB1	8
GO:1902003	regulation of amyloid-beta formation	8/896	48/18722	0.00183278215717545	0.010002413430713	SORL1/TNF/IFNGR1/PICALM/RTN3/ROCK1/SP1/PRNP	8
GO:0002820	negative regulation of adaptive immune response	9/896	59/18722	0.00184596711893575	0.0100532722362145	PTPRC/PTPN6/LILRB1/HLA-F/NCKAP1L/TNFRSF14/BCL6/SAMSN1/AHR	9
GO:0048010	vascular endothelial growth factor receptor signaling pathway	9/896	59/18722	0.00184596711893575	0.0100532722362145	IL1B/PRKCB/FYN/HHEX/PTK2B/MAPKAPK3/ITGA5/PAK2/HIF1A	9
GO:0032490	detection of molecule of bacterial origin	4/896	12/18722	0.00189407628022935	0.0102511969256868	LY96/TLR2/TLR4/TLR1	4
GO:0034154	toll-like receptor 7 signaling pathway	4/896	12/18722	0.00189407628022935	0.0102511969256868	SCIMP/PIK3AP1/UNC93B1/DDX3X	4
GO:0043380	regulation of memory T cell differentiation	4/896	12/18722	0.00189407628022935	0.0102511969256868	FGL2/HLA-DRA/HLA-DRB1/BCL6	4
GO:0140052	cellular response to oxidised low-density lipoprotein particle stimulus	4/896	12/18722	0.00189407628022935	0.0102511969256868	CD36/CD68/MYD88/TLR4	4
GO:1905245	regulation of aspartic-type peptidase activity	4/896	12/18722	0.00189407628022935	0.0102511969256868	LYN/GRN/SORL1/PICALM	4
GO:0042982	amyloid precursor protein metabolic process	12/896	95/18722	0.00189413579034513	0.0102511969256868	LYN/SORL1/TNF/FKBP1A/IFNGR1/PICALM/RTN3/ROCK1/ADAM10/SP1/ADAM17/PRNP	12
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	30/896	355/18722	0.00189813171008556	0.0102621445157537	FOS/VIM/ZEB2/SPI1/EGR1/ARRB2/USP15/JAK2/ZYX/TGFB1/NOTCH2/SORL1/C20orf27/JUN/UBE2D1/HSPA1A/FKBP1A/SKIL/DDX5/STAT3/SDCBP/UBE2D3/ZBTB7A/TGFBR2/DUSP22/ADAM17/CREBBP/EP300/FAM89B/CREB1	30
GO:0006401	RNA catabolic process	25/896	278/18722	0.00191018845807163	0.0103166045383495	ZFP36/VIM/ZFP36L2/TNFRSF1B/SLC11A1/BTG2/PABPC1/RNASET2/RNASE6/OAS2/MYD88/ZFP36L1/HSPA1A/NUDT16/DDX5/ROCK1/ATM/YBX1/HNRNPU/DICER1/XRN2/CELF1/RNH1/XRN1/SMG1	25
GO:1901186	positive regulation of ERBB signaling pathway	7/896	38/18722	0.00193009435186529	0.0104132995062774	NCF1/PLAUR/HBEGF/CCDC88A/SHKBP1/ADAM17/NUP62	7
GO:0034446	substrate adhesion-dependent cell spreading	13/896	108/18722	0.00194403809512675	0.0104776602411961	FLNA/GBP1/MEGF9/ITGA4/MYADM/FERMT3/PARVG/RHOA/PREX1/CDC42/LIMS1/CORO1C/CIB1	13
GO:0043550	regulation of lipid kinase activity	10/896	71/18722	0.0019545807345193	0.01052357598368	LYN/KLF4/FGR/SOCS3/TGFB1/PTK2B/CDC42/RB1/DGKZ/PIP4K2A	10
GO:0031397	negative regulation of protein ubiquitination	11/896	83/18722	0.00195903683582381	0.0105257753957847	TSPO/ISG15/TNFAIP3/ARRB2/FYN/HSPA1A/DTX3L/CHP1/SPOPL/IVNS1ABP/TRIP12	11
GO:0048678	response to axon injury	11/896	83/18722	0.00195903683582381	0.0105257753957847	AIF1/TYROBP/TSPO/LGALS1/LYN/FLNA/KLF4/JAK2/GRN/PTEN/MAX	11
GO:0010634	positive regulation of epithelial cell migration	18/896	176/18722	0.00198635937631848	0.0106505722847757	TMSB4X/RHOB/PTGS2/GLIPR2/GRN/CTSH/TGFB1/HBEGF/MAP3K3/PTK2B/RRAS/PFN1/HIF1A/HMOX1/TGFBR2/SP1/ADAM17/CIB1	18
GO:0043534	blood vessel endothelial cell migration	18/896	176/18722	0.00198635937631848	0.0106505722847757	TMSB4X/KLF4/PTGS2/NR4A1/MEF2C/GPX1/TGFB1/TNF/RHOA/MAP3K3/PTK2B/HIF1A/PRCP/HMOX1/MYH9/SP1/ADAM17/CIB1	18
GO:0043542	endothelial cell migration	25/896	279/18722	0.00200578096764382	0.0107436321449181	TMSB4X/KLF4/RHOB/PTGS2/CYP1B1/NR4A1/MEF2C/GPX1/GRN/TGFB1/TNF/RHOA/MAP3K3/PTK2B/GLUL/SP100/RRAS/PTEN/HIF1A/PRCP/HMOX1/MYH9/SP1/ADAM17/CIB1	25
GO:0051047	positive regulation of secretion	27/896	310/18722	0.00204311895244015	0.0109323679749395	S100A8/IL1B/CYBA/ITGB2/FGR/HLA-DRB1/GNAI2/RETN/JAK2/HLA-F/TLR2/TGFB1/SYK/ITGAM/TLR4/CD33/RAB27A/PTAFR/SERP1/GLUL/NADK/RAB8B/SDCBP/HIF1A/ACSL4/IRS2/CREB1	27
GO:0042306	regulation of protein import into nucleus	9/896	60/18722	0.00208133652046908	0.0111254175158887	FLNA/CD36/PTGS2/JAK2/TGFB1/HCLS1/CHP1/MAPK1/NUP62	9
GO:0044706	multi-multicellular organism process	21/896	220/18722	0.00208350299258515	0.0111255637211862	IL1B/FOS/RGS2/VMP1/JUNB/NAMPT/FOSB/ARHGDIB/TIMP1/PTGS2/LGALS9/UCP2/PTAFR/CTSB/CAPN2/ADCY7/MAPK1/ACSL4/LNPEP/TGFBR2/SP3	21
GO:0032692	negative regulation of interleukin-1 production	8/896	49/18722	0.00210018396856977	0.0111523596792775	CARD16/TNFAIP3/ARRB2/CX3CR1/NLRP3/CD33/SERPINB1/CARD8	8
GO:0034332	adherens junction organization	8/896	49/18722	0.00210018396856977	0.0111523596792775	ACTB/NUMB/CSK/PAK2/CDC42/ADAM10/HIPK1/PLEC	8
GO:0070741	response to interleukin-6	8/896	49/18722	0.00210018396856977	0.0111523596792775	SPI1/JAK2/SELPLG/IL6R/JAK1/STAT3/PTPN2/NFKB1	8
GO:1904894	positive regulation of receptor signaling pathway via STAT	8/896	49/18722	0.00210018396856977	0.0111523596792775	CYP1B1/JAK2/IL10RA/TGFB1/TNF/IL6R/CD300A/PTK2B	8
GO:0045834	positive regulation of lipid metabolic process	16/896	149/18722	0.00210138674979657	0.0111523596792775	IL1B/CD74/LYN/FGR/PTGS2/TGFB1/TNF/LPGAT1/PTK2B/CAPN2/CHP1/ELOVL5/CDC42/DGKZ/IRS2/CREB1	16
GO:0051592	response to calcium ion	16/896	149/18722	0.00210138674979657	0.0111523596792775	FOS/TXNIP/DUSP1/JUNB/FOSB/MEF2C/IQGAP1/RASGRP2/PTK2B/CALM2/MEF2A/JUND/ALOX5AP/SLC25A24/PPP3CA/WNK1	16
GO:0046629	gamma-delta T cell activation	5/896	20/18722	0.00210924920196033	0.0111712882885903	PTPRC/JAML/LILRB1/NCKAP1L/SYK	5
GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	5/896	20/18722	0.00210924920196033	0.0111712882885903	LRRK2/HSPA1A/TMBIM6/GRINA/HERPUD1	5
GO:0045930	negative regulation of mitotic cell cycle	22/896	235/18722	0.00211280952321089	0.0111787612718412	DUSP1/ZFP36L2/KLF4/BTG2/TGFB1/TNF/BCL6/ZFP36L1/TIMP2/BTG1/TAOK3/CDKN1A/PTEN/RB1/ATM/NABP1/FOXN3/TAOK1/WAC/CTDSP1/ZNF207/DYNC1LI1	22
GO:0010976	positive regulation of neuron projection development	17/896	163/18722	0.00212306810749001	0.0112216231982272	S100A9/RGS2/LYN/FLNA/ACTR2/IQGAP1/GRN/FYN/PTK2B/SETX/RAP1A/TWF2/CFLAR/PLXNB2/DBNL/DYNLT1/EP300	17
GO:0071479	cellular response to ionizing radiation	10/896	72/18722	0.0021745789831113	0.0114175352883336	CYBA/NAMPT/EGR1/IFI16/RHOB/GRB2/CDKN1A/TANK/NIPBL/ATM	10
GO:0001773	myeloid dendritic cell activation	6/896	29/18722	0.00217769563661351	0.0114175352883336	PYCARD/SPI1/DOCK2/NOTCH2/TGFBR2/LTBR	6
GO:0010592	positive regulation of lamellipodium assembly	6/896	29/18722	0.00217769563661351	0.0114175352883336	ACTR2/RAC2/ACTR3/TWF2/CDC42/BRK1	6
GO:0010955	negative regulation of protein processing	6/896	29/18722	0.00217769563661351	0.0114175352883336	CARD16/LRRK2/CTSZ/CAST/CARD8/PRNP	6
GO:0060969	negative regulation of gene silencing	6/896	29/18722	0.00217769563661351	0.0114175352883336	NEAT1/TGFB1/TNF/STAT3/ADAR/PPP3CA	6
GO:0090025	regulation of monocyte chemotaxis	6/896	29/18722	0.00217769563661351	0.0114175352883336	AIF1/DUSP1/LYN/CX3CR1/CCR1/CCR2	6
GO:1903318	negative regulation of protein maturation	6/896	29/18722	0.00217769563661351	0.0114175352883336	CARD16/LRRK2/CTSZ/CAST/CARD8/PRNP	6
GO:1903902	positive regulation of viral life cycle	6/896	29/18722	0.00217769563661351	0.0114175352883336	CD74/LGALS1/HLA-DRB1/LGALS9/CD4/TRIM38	6
GO:0045727	positive regulation of translation	15/896	136/18722	0.00219739479957056	0.0115092148565624	VIM/PABPC1/TNF/RHOA/RPS9/PTAFR/PTK2B/SERP1/PPP1R15A/CNBP/EIF2S3/MAPK1/PLXNB2/EEF2/DDX3X	15
GO:0035335	peptidyl-tyrosine dephosphorylation	12/896	97/18722	0.00226475181034164	0.0118381649905396	DUSP1/PTPRC/DUSP6/PTPN6/PTPRE/PTP4A2/PTPN18/PTEN/SSH2/DUSP23/DUSP22/PTPN2	12
GO:0120162	positive regulation of cold-induced thermogenesis	12/896	97/18722	0.00226475181034164	0.0118381649905396	CD36/PLAC8/CEBPB/JAK2/UCP2/SYK/CCR2/CXCR4/STAT6/ACSL1/KDM6B/DECR1	12
GO:0043030	regulation of macrophage activation	9/896	61/18722	0.00234000846874664	0.0122192610903125	PTPRC/CD74/CCL3/LRRK2/GRN/TLR4/JUND/CD84/PJA2	9
GO:0055072	iron ion homeostasis	11/896	85/18722	0.00237512719849855	0.0123777921436783	B2M/SLC11A1/FTL/FTH1/FBXL5/PICALM/ATP6V0D1/ATP6V1A/HIF1A/NCOA4/HMOX1	11
GO:0071277	cellular response to calcium ion	11/896	85/18722	0.00237512719849855	0.0123777921436783	FOS/JUNB/FOSB/MEF2C/IQGAP1/RASGRP2/MEF2A/JUND/ALOX5AP/SLC25A24/WNK1	11
GO:0050871	positive regulation of B cell activation	16/896	152/18722	0.00257568114342497	0.0134095271541074	PTPRC/CD74/TNFSF13B/MEF2C/NCKAP1L/TGFB1/SYK/BST1/STAT6/TLR4/INPP5D/BCL6/BTK/SH3KBP1/CDKN1A/IRS2	16
GO:0032480	negative regulation of type I interferon production	6/896	30/18722	0.00261351826542676	0.0135419601049334	PYCARD/LILRB1/REL/SIRPA/CYLD/NMI	6
GO:0070229	negative regulation of lymphocyte apoptotic process	6/896	30/18722	0.00261351826542676	0.0135419601049334	CD74/TSC22D3/BCL6/DOCK8/HIF1A/IRS2	6
GO:0022411	cellular component disassembly	35/896	443/18722	0.00261426943355776	0.0135419601049334	CTSS/LCP1/TSPO/VMP1/CST3/PLEK/IRAK3/CX3CR1/VPS13C/PRKCB/TGFB1/CAPG/TNF/ITGAM/SETX/CFL1/GABARAP/CAPZA1/MTPN/CAPZA2/TWF2/ATG3/BNIP3L/HIF1A/ADAM10/TOMM7/FLII/ARID1A/CALCOCO2/DICER1/TAOK1/CHMP1B/LAMP2/RB1CC1/CIB1	35
GO:0010543	regulation of platelet activation	7/896	40/18722	0.00262438934990297	0.0135419601049334	FCER1G/PLEK/LYN/JAK2/SYK/TLR4/SH2B3	7
GO:0034122	negative regulation of toll-like receptor signaling pathway	7/896	40/18722	0.00262438934990297	0.0135419601049334	LYN/TNFAIP3/ARRB2/IRAK3/LILRA2/CD300LF/CD300A	7
GO:0071276	cellular response to cadmium ion	7/896	40/18722	0.00262438934990297	0.0135419601049334	CYBB/FOS/NCF1/JUN/UBE2D3/MAPK1/HMOX1	7
GO:0034112	positive regulation of homotypic cell-cell adhesion	4/896	13/18722	0.00263296877370168	0.0135419601049334	LGALS1/PLAUR/JAK2/JAK1	4
GO:0036005	response to macrophage colony-stimulating factor	4/896	13/18722	0.00263296877370168	0.0135419601049334	TLR2/CSF1R/TLR4/PTPN2	4
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	4/896	13/18722	0.00263296877370168	0.0135419601049334	TLR2/CSF1R/TLR4/PTPN2	4
GO:0043379	memory T cell differentiation	4/896	13/18722	0.00263296877370168	0.0135419601049334	FGL2/HLA-DRA/HLA-DRB1/BCL6	4
GO:1902947	regulation of tau-protein kinase activity	4/896	13/18722	0.00263296877370168	0.0135419601049334	C5AR1/EGR1/SORL1/RB1	4
GO:1903054	negative regulation of extracellular matrix organization	4/896	13/18722	0.00263296877370168	0.0135419601049334	CST3/TNFRSF1B/TGFB1/TNFRSF1A	4
GO:1904375	regulation of protein localization to cell periphery	14/896	125/18722	0.00263496704983514	0.0135419601049334	ACTB/GBP1/TGFB1/NUMB/CSK/TNF/RHOG/RAP1A/PICALM/RHOQ/ADAM10/PRNP/STX7/CIB1	14
GO:0007252	I-kappaB phosphorylation	5/896	21/18722	0.00266055528036355	0.0136330522297249	CX3CR1/TLR2/TNF/TLR4/SIRPA	5
GO:0030502	negative regulation of bone mineralization	5/896	21/18722	0.00266055528036355	0.0136330522297249	SRGN/CCL3/CCR1/PTK2B/HIF1A	5
GO:0150105	protein localization to cell-cell junction	5/896	21/18722	0.00266055528036355	0.0136330522297249	FLNA/ACTB/PECAM1/JAK1/PAK2	5
GO:0007040	lysosome organization	10/896	74/18722	0.00267424280853738	0.0136762407543785	LAPTM5/CORO1A/LRRK2/LYST/PPT1/GRN/TPP1/ATP6AP2/LAMTOR1/HOOK3	10
GO:0080171	lytic vacuole organization	10/896	74/18722	0.00267424280853738	0.0136762407543785	LAPTM5/CORO1A/LRRK2/LYST/PPT1/GRN/TPP1/ATP6AP2/LAMTOR1/HOOK3	10
GO:0014009	glial cell proliferation	8/896	51/18722	0.00272638908448864	0.0139155541005156	IL1B/TSPO/LYN/TNF/PTK2B/EEF2/DICER1/CREB1	8
GO:0071622	regulation of granulocyte chemotaxis	8/896	51/18722	0.00272638908448864	0.0139155541005156	CD74/C5AR1/CXCL8/RAC2/NCKAP1L/BST1/CSF1R/MAPK1	8
GO:0006913	nucleocytoplasmic transport	26/896	301/18722	0.002740373048125	0.0139595300913791	IL1B/TXNIP/NFKBIA/LRRK2/FLNA/CD36/NUP214/PTGS2/JAK2/MX2/TGFB1/SYK/HHEX/AKAP13/HCLS1/SP100/CHP1/CDKN1A/PRKACA/STAT3/MAPK1/NUP50/PPP3CA/PPP1R12A/NUP62/SMG1	26
GO:0051169	nuclear transport	26/896	301/18722	0.002740373048125	0.0139595300913791	IL1B/TXNIP/NFKBIA/LRRK2/FLNA/CD36/NUP214/PTGS2/JAK2/MX2/TGFB1/SYK/HHEX/AKAP13/HCLS1/SP100/CHP1/CDKN1A/PRKACA/STAT3/MAPK1/NUP50/PPP3CA/PPP1R12A/NUP62/SMG1	26
GO:0050767	regulation of neurogenesis	30/896	364/18722	0.00276345682015503	0.0140633453244876	IL1B/TSPO/TNFRSF1B/B2M/LYN/ACTR2/CX3CR1/TLR2/TGFB1/NUMB/SORL1/CXCR4/PLXNC1/TNF/ARHGAP4/SKIL/NIN/SHTN1/PAK1/TWF2/PTEN/HIF1A/PLXNB2/DBNL/SPEN/DICER1/PPP3CA/DYNLT1/HOOK3/CTDSP1	30
GO:0019693	ribose phosphate metabolic process	32/896	396/18722	0.00276728102666015	0.0140690406839291	TMSB4X/LRRK2/DPYD/GIMAP7/PPT1/TGFB1/SULT1A1/TKT/UPP1/RHOA/KYNU/ACSL1/FBP1/NUDT16/PDK4/G6PD/PRKAG2/RHOQ/ELOVL5/ATP6V1A/STAT3/ADCY7/HIF1A/PGK1/PYGL/NUDT3/ACSL4/ZBTB7A/ADPGK/FAR1/GNAI3/EP300	32
GO:0043393	regulation of protein binding	19/896	196/18722	0.00279227339927152	0.0141822401851671	CARD16/B2M/LRRK2/IFIT2/ACTB/ARRB2/ITGA4/CTSZ/SORL1/FKBP1A/RALB/STK4/DTX3L/CDKN1A/CDC42/PRKACA/ROCK1/TMBIM6/EP300	19
GO:0030100	regulation of endocytosis	20/896	211/18722	0.00285008037110582	0.0144617248879233	CD14/B2M/LRRK2/CD36/ARRB2/LILRB1/PPT1/NCKAP1L/SYK/NUMB/RIN3/MCTP1/CD300A/ANKRD13D/PICALM/CDC42/ROCK1/SDCBP/BMP2K/PPP3CA	20
GO:0044843	cell cycle G1/S phase transition	22/896	241/18722	0.00288611037901049	0.0146302729836585	AIF1/KLF4/PTPN6/BACH1/BID/EIF4EBP1/PSME2/PSME1/CDKN1A/KMT2E/PTEN/RB1/MAP3K11/PIAS1/ATM/PPP3CA/WAC/LSM10/ADAM17/DDX3X/TAF10/CTDSP1	22
GO:0031623	receptor internalization	13/896	113/18722	0.00291388662183614	0.01474233883285	FCER1G/ITGB2/CD36/ARRB2/CXCL8/LILRB1/SYK/NUMB/RIN3/ANKRD13D/PICALM/GRB2/SDCBP	13
GO:0044106	cellular amine metabolic process	13/896	113/18722	0.00291388662183614	0.01474233883285	ITGB2/SLC7A7/NR4A2/OAZ1/SULT1A1/SAT1/ITGAM/GCH1/KYNU/NAAA/MTPN/SAT2/HNMT	13
GO:1904589	regulation of protein import	9/896	63/18722	0.00293367324327977	0.0148280219031079	FLNA/CD36/PTGS2/JAK2/TGFB1/HCLS1/CHP1/MAPK1/NUP62	9
GO:0033077	T cell differentiation in thymus	10/896	75/18722	0.00295637634979527	0.0149137860284047	IL1B/PTPRC/ZFP36L2/CD74/B2M/MAFB/DOCK2/ZFP36L1/PTPN2/ADAM17	10
GO:0051453	regulation of intracellular pH	10/896	75/18722	0.00295637634979527	0.0149137860284047	LRRK2/SLC11A1/DMXL2/PPT1/GRN/TCIRG1/HVCN1/CHP1/ATP6V0D1/ATP6AP2	10
GO:0050856	regulation of T cell receptor signaling pathway	7/896	41/18722	0.00303634497061909	0.0152727564721372	LAPTM5/GBP1/PTPN6/CD300A/DGKZ/PTPN2/PRNP	7
GO:0071470	cellular response to osmotic stress	7/896	41/18722	0.00303634497061909	0.0152727564721372	TSPO/PTGS2/RCSD1/ZFP36L1/MICU1/CAB39/DDX3X	7
GO:0071634	regulation of transforming growth factor beta production	7/896	41/18722	0.00303634497061909	0.0152727564721372	TYROBP/PTGS2/LILRB1/LGALS9/HIF1A/ATP6AP2/CREB1	7
GO:0035196	production of miRNAs involved in gene silencing by miRNA	8/896	52/18722	0.00308967287111478	0.0155109928597181	TGFB1/TNF/DDX5/STAT3/ADAR/DICER1/PPP3CA/DDX3X	8
GO:0060147	regulation of posttranscriptional gene silencing	8/896	52/18722	0.00308967287111478	0.0155109928597181	ZFP36/NEAT1/TGFB1/TNF/DDX5/STAT3/ADAR/PPP3CA	8
GO:0002828	regulation of type 2 immune response	6/896	31/18722	0.00311160393447021	0.0155610115992111	CD74/CD86/NLRP3/CCR2/STAT6/BCL6	6
GO:0045066	regulatory T cell differentiation	6/896	31/18722	0.00311160393447021	0.0155610115992111	HLA-DRA/IRF1/HLA-DRB1/LILRB2/LGALS9/BCL6	6
GO:0060055	angiogenesis involved in wound healing	6/896	31/18722	0.00311160393447021	0.0155610115992111	TNFAIP3/GPX1/CXCR4/TNF/ALOX5/PRCP	6
GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	6/896	31/18722	0.00311160393447021	0.0155610115992111	TNFAIP3/GPX1/CFLAR/HMOX1/DDX3X/PEA15	6
GO:0050829	defense response to Gram-negative bacterium	11/896	88/18722	0.00313068757094501	0.0156414083155476	LYZ/MPEG1/PYCARD/SLC11A1/CASP1/CD4/RNASE6/TREM1/TNFRSF14/IL6R/TLR4	11
GO:1904892	regulation of receptor signaling pathway via STAT	13/896	114/18722	0.00314865188762972	0.0157160637884474	PTPRC/CYP1B1/SOCS3/JAK2/IL10RA/TGFB1/TNF/IL6R/CD300A/SH2B3/PTK2B/PARP14/PTPN2	13
GO:0006576	cellular biogenic amine metabolic process	12/896	101/18722	0.00318374572080047	0.0158759937621124	ITGB2/NR4A2/OAZ1/SULT1A1/SAT1/ITGAM/GCH1/KYNU/NAAA/MTPN/SAT2/HNMT	12
GO:0014823	response to activity	10/896	76/18722	0.00326174924832889	0.0162493849047496	CYBA/SOD2/SCO2/CXCR4/METRNL/KDM6B/PTEN/HIF1A/CAB39/CREB1	10
GO:0070542	response to fatty acid	9/896	64/18722	0.00327199224719422	0.0162848150025427	CD36/PTGS2/UCP2/TLR2/TBXAS1/PTAFR/ACSL1/PDK4/CREB1	9
GO:0006907	pinocytosis	5/896	22/18722	0.00330913332552498	0.0163756445538111	PYCARD/PPT1/DOCK2/MAPKAPK3/CDC42	5
GO:0035561	regulation of chromatin binding	5/896	22/18722	0.00330913332552498	0.0163756445538111	PARP9/DTX3L/CTBP2/MBD2/PPP3CA	5
GO:0060965	negative regulation of gene silencing by miRNA	5/896	22/18722	0.00330913332552498	0.0163756445538111	NEAT1/TGFB1/TNF/STAT3/PPP3CA	5
GO:0072574	hepatocyte proliferation	5/896	22/18722	0.00330913332552498	0.0163756445538111	TNFAIP3/CEBPB/NOTCH2/SULF2/CFLAR	5
GO:0072575	epithelial cell proliferation involved in liver morphogenesis	5/896	22/18722	0.00330913332552498	0.0163756445538111	TNFAIP3/CEBPB/NOTCH2/SULF2/CFLAR	5
GO:2000114	regulation of establishment of cell polarity	5/896	22/18722	0.00330913332552498	0.0163756445538111	PTK2B/SHTN1/DOCK8/ROCK1/RAP1B	5
GO:0009267	cellular response to starvation	16/896	156/18722	0.00334321857517252	0.0165285929747835	LRRK2/IFI16/UCP2/UPP1/JUN/GLUL/RALB/PDK4/GABARAP/PRKAG2/CDKN1A/KLF10/MAPK1/ATF3/MAX/LAMP2	16
GO:0046916	cellular transition metal ion homeostasis	13/896	115/18722	0.00339858573135168	0.0167863669408928	S100A9/S100A8/SLC11A1/FTL/FTH1/SCO2/ATP6V0D1/ATP6V1A/HIF1A/NCOA4/HMOX1/SLC31A2/PRNP	13
GO:0010657	muscle cell apoptotic process	11/896	89/18722	0.00342157427748722	0.0168838783844507	SOD2/ARRB2/JAK2/APAF1/PTK2B/CAPN2/STK4/CFLAR/PTEN/GNB1/HMOX1	11
GO:0060966	regulation of gene silencing by RNA	8/896	53/18722	0.0034895008057418	0.0171532732519458	ZFP36/NEAT1/TGFB1/TNF/DDX5/STAT3/ADAR/PPP3CA	8
GO:1990090	cellular response to nerve growth factor stimulus	8/896	53/18722	0.0034895008057418	0.0171532732519458	CORO1A/ACAP2/ARPC3/RAP1A/PTEN/EEF2/CREB1/CIB1	8
GO:0010591	regulation of lamellipodium assembly	7/896	42/18722	0.00349595647895839	0.0171532732519458	ACTR2/WAS/RAC2/ACTR3/TWF2/CDC42/BRK1	7
GO:0016601	Rac protein signal transduction	7/896	42/18722	0.00349595647895839	0.0171532732519458	AIF1/RAC2/RHOG/GABARAP/DBNL/BRK1/DYNLT1	7
GO:0043507	positive regulation of JUN kinase activity	7/896	42/18722	0.00349595647895839	0.0171532732519458	SYK/TNF/FGD2/PTK2B/PAK1/TAOK3/MAP3K11	7
GO:0051452	intracellular pH reduction	7/896	42/18722	0.00349595647895839	0.0171532732519458	SLC11A1/DMXL2/PPT1/GRN/TCIRG1/ATP6V0D1/ATP6AP2	7
GO:0031669	cellular response to nutrient levels	20/896	215/18722	0.00353409248803124	0.0172446291523376	NAMPT/LRRK2/IFI16/CD68/UCP2/UPP1/JUN/GLUL/RALB/PDK4/GABARAP/PRKAG2/CDKN1A/KLF10/MAPK1/ATF3/HMOX1/MAX/USF2/LAMP2	20
GO:0035563	positive regulation of chromatin binding	4/896	14/18722	0.00354773181945803	0.0172446291523376	PARP9/DTX3L/CTBP2/MBD2	4
GO:0043249	erythrocyte maturation	4/896	14/18722	0.00354773181945803	0.0172446291523376	KLF2/G6PD/PTBP3/ZBTB7A	4
GO:0045059	positive thymic T cell selection	4/896	14/18722	0.00354773181945803	0.0172446291523376	PTPRC/CD74/DOCK2/PTPN2	4
GO:0045579	positive regulation of B cell differentiation	4/896	14/18722	0.00354773181945803	0.0172446291523376	NCKAP1L/SYK/INPP5D/BTK	4
GO:0046348	amino sugar catabolic process	4/896	14/18722	0.00354773181945803	0.0172446291523376	ALDH1A1/NAGK/MGAT1/CTBS	4
GO:0051764	actin crosslink formation	4/896	14/18722	0.00354773181945803	0.0172446291523376	AIF1/LCP1/FLNA/MARCKS	4
GO:0061043	regulation of vascular wound healing	4/896	14/18722	0.00354773181945803	0.0172446291523376	TNFAIP3/CXCR4/TNF/ALOX5	4
GO:0090715	immunological memory formation process	4/896	14/18722	0.00354773181945803	0.0172446291523376	FGL2/HLA-DRA/HLA-DRB1/BCL6	4
GO:1905049	negative regulation of metallopeptidase activity	4/896	14/18722	0.00354773181945803	0.0172446291523376	TIMP1/SORL1/TIMP2/PICALM	4
GO:0010827	regulation of glucose transmembrane transport	10/896	77/18722	0.00359168286101578	0.0174419631747368	IL1B/PRKCB/TNF/OSBPL8/MEF2A/RAP1A/PRKAG2/RHOQ/IRS2/PEA15	10
GO:0003170	heart valve development	9/896	65/18722	0.00364026120994104	0.0176449194342063	TNFRSF1B/MEF2C/TGFB1/NOTCH2/TNFRSF1A/ROCK1/RB1/TGFBR2/MDM4	9
GO:0048524	positive regulation of viral process	9/896	65/18722	0.00364026120994104	0.0176449194342063	CD74/LGALS1/PABPC1/HLA-DRB1/LGALS9/CD4/TRIM38/ADAR/DDX3X	9
GO:0021782	glial cell development	13/896	116/18722	0.00366439557966784	0.0176920470009094	S100A9/S100A8/VIM/C5AR1/LYN/GRN/TLR2/TNF/TLR4/IFNGR1/PTEN/DICER1/PLEC	13
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	6/896	32/18722	0.00367719723283658	0.0176920470009094	ZEB2/C20orf27/SDCBP/ADAM17/CREBBP/EP300	6
GO:0045761	regulation of adenylate cyclase activity	6/896	32/18722	0.00367719723283658	0.0176920470009094	GNAI2/P2RY13/CAP1/CCR2/TIMP2/GNAI3	6
GO:0090022	regulation of neutrophil chemotaxis	6/896	32/18722	0.00367719723283658	0.0176920470009094	CD74/C5AR1/CXCL8/RAC2/NCKAP1L/BST1	6
GO:1900745	positive regulation of p38MAPK cascade	6/896	32/18722	0.00367719723283658	0.0176920470009094	IL1B/NCF1/SPI1/GADD45B/MAP3K3/PJA2	6
GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	6/896	32/18722	0.00367719723283658	0.0176920470009094	LRRK2/HSPA1A/PTPN2/TMBIM6/GRINA/HERPUD1	6
GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	6/896	32/18722	0.00367719723283658	0.0176920470009094	ZEB2/C20orf27/SDCBP/ADAM17/CREBBP/EP300	6
GO:1905476	negative regulation of protein localization to membrane	6/896	32/18722	0.00367719723283658	0.0176920470009094	GBP1/TGFB1/NUMB/CSK/PICALM/RHOQ	6
GO:0030004	cellular monovalent inorganic cation homeostasis	12/896	103/18722	0.00374501467792159	0.0179850612556511	LRRK2/SLC11A1/DMXL2/PPT1/GRN/SLC8A1/TCIRG1/HVCN1/CHP1/ATP6V0D1/MAPK1/ATP6AP2	12
GO:0046425	regulation of receptor signaling pathway via JAK-STAT	12/896	103/18722	0.00374501467792159	0.0179850612556511	PTPRC/CYP1B1/SOCS3/JAK2/IL10RA/TNF/IL6R/CD300A/SH2B3/PTK2B/PARP14/PTPN2	12
GO:0010821	regulation of mitochondrion organization	15/896	144/18722	0.00381514160109498	0.0183049367779474	TSPO/PYCARD/TNFSF10/LRRK2/ARRB2/PLAUR/GPX1/VPS13C/STAT2/BID/HSPA1A/CHCHD10/BNIP3L/HIF1A/EP300	15
GO:0031050	dsRNA processing	8/896	54/18722	0.00392826006812859	0.0188129655748958	TGFB1/TNF/DDX5/STAT3/ADAR/DICER1/PPP3CA/DDX3X	8
GO:0070918	production of small RNA involved in gene silencing by RNA	8/896	54/18722	0.00392826006812859	0.0188129655748958	TGFB1/TNF/DDX5/STAT3/ADAR/DICER1/PPP3CA/DDX3X	8
GO:0042088	T-helper 1 type immune response	7/896	43/18722	0.00400665096873402	0.0191355295577462	IL1B/SLC11A1/HLA-DRB1/CCR2/STAT6/TLR4/SPN	7
GO:0071604	transforming growth factor beta production	7/896	43/18722	0.00400665096873402	0.0191355295577462	TYROBP/PTGS2/LILRB1/LGALS9/HIF1A/ATP6AP2/CREB1	7
GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	7/896	43/18722	0.00400665096873402	0.0191355295577462	SOD2/MEF2C/RHOA/CDKN1A/PTEN/HMOX1/GNA13	7
GO:1903169	regulation of calcium ion transmembrane transport	16/896	159/18722	0.00403501092709804	0.0192156604252947	CYBA/VMP1/CORO1A/LYN/PTPN6/SLC8A1/KCNE3/FYN/PTK2B/FKBP1A/AHNAK/CALM2/G6PD/PRKACA/DIAPH1/PRNP	16
GO:0014015	positive regulation of gliogenesis	9/896	66/18722	0.00404025130389074	0.0192156604252947	IL1B/TSPO/TNFRSF1B/LYN/TLR2/TGFB1/CXCR4/TNF/DICER1	9
GO:0045600	positive regulation of fat cell differentiation	9/896	66/18722	0.00404025130389074	0.0192156604252947	ZFP36/PTGS2/CEBPB/METRNL/ZFP36L1/STK4/ZNF385A/HNRNPU/CREB1	9
GO:0050853	B cell receptor signaling pathway	14/896	131/18722	0.00404910429541574	0.0192156604252947	MNDA/PTPRC/LYN/MEF2C/PTPN6/PRKCB/NCKAP1L/SYK/LAT2/NFAM1/CD300A/BTK/CMTM3/MAPK1	14
GO:1903076	regulation of protein localization to plasma membrane	12/896	104/18722	0.00405407978926046	0.0192156604252947	ACTB/GBP1/TGFB1/NUMB/CSK/TNF/RHOG/PICALM/RHOQ/PRNP/STX7/CIB1	12
GO:0002363	alpha-beta T cell lineage commitment	5/896	23/18722	0.00406406969194851	0.0192156604252947	STAT6/RHOA/IL6R/SPN/STAT3	5
GO:0006622	protein targeting to lysosome	5/896	23/18722	0.00406406969194851	0.0192156604252947	LAPTM5/SORL1/NCOA4/M6PR/LAMP2	5
GO:0035162	embryonic hemopoiesis	5/896	23/18722	0.00406406969194851	0.0192156604252947	SH2B3/STK4/HIF1A/TGFBR2/KMT2A	5
GO:0045723	positive regulation of fatty acid biosynthetic process	5/896	23/18722	0.00406406969194851	0.0192156604252947	IL1B/CD74/PTGS2/LPGAT1/ELOVL5	5
GO:0051457	maintenance of protein location in nucleus	5/896	23/18722	0.00406406969194851	0.0192156604252947	SP100/CHCHD10/SUN2/HNRNPU/MORC3	5
GO:0072576	liver morphogenesis	5/896	23/18722	0.00406406969194851	0.0192156604252947	TNFAIP3/CEBPB/NOTCH2/SULF2/CFLAR	5
GO:0015833	peptide transport	23/896	264/18722	0.00420378569977859	0.0198582101948669	S100A8/IL1B/CD74/HLA-DRB1/JAK2/IL1RN/UCP2/TNF/TCIRG1/ALOX5/MGST1/TAP1/SERP1/TAPBP/GLUL/MIDN/CYB5R4/NADK/RAB8B/HIF1A/ACSL4/IRS2/PPP3CA	23
GO:0009308	amine metabolic process	13/896	118/18722	0.00424655574699251	0.0200238770989194	ITGB2/SLC7A7/NR4A2/OAZ1/SULT1A1/SAT1/ITGAM/GCH1/KYNU/NAAA/MTPN/SAT2/HNMT	13
GO:0022612	gland morphogenesis	13/896	118/18722	0.00424655574699251	0.0200238770989194	CRIP1/MSN/TNFAIP3/CEBPB/TGFB1/NOTCH2/CSF1R/SULF2/TNF/STAT6/CDC42/CFLAR/TGFBR2	13
GO:0044772	mitotic cell cycle phase transition	33/896	424/18722	0.00428567263508242	0.0201854163121947	AIF1/DUSP1/ZFP36L2/KLF4/PTPN6/BACH1/BID/ZFP36L1/EIF4EBP1/PSME2/CALM2/PSME1/TAOK3/CCNI/CDKN1A/KMT2E/CCNY/PTEN/RB1/PIAS1/ATM/NABP1/PPP3CA/FOXN3/TAOK1/WAC/LSM10/ADAM17/DDX3X/TAF10/CTDSP1/ZNF207/DYNC1LI1	33
GO:0046578	regulation of Ras protein signal transduction	18/896	189/18722	0.00428857624014135	0.0201854163121947	ARHGDIB/NOTCH2/LPAR6/GPR65/BCL6/CYTH4/FBP1/AKAP13/TIMP2/CYTH1/GABARAP/ARHGEF3/MYO9B/SHOC2/CDC42SE1/DYNLT1/ARHGDIA/NUP62	18
GO:0021700	developmental maturation	24/896	280/18722	0.00430164966125975	0.0202286436602278	KLF2/LRRK2/CLEC7A/SNX10/NR4A2/CX3CR1/RAB32/RHOA/LYL1/BTK/PTK2B/G6PD/PICALM/CDKN1A/PRKACA/PTBP3/SCLT1/PTEN/RB1/PFN1/HIF1A/ATP6AP2/ZBTB7A/BLOC1S6	24
GO:0051279	regulation of release of sequestered calcium ion into cytosol	10/896	79/18722	0.00433067742173552	0.0203283874282008	CYBA/CORO1A/LYN/PTPN6/SLC8A1/PTK2B/FKBP1A/CALM2/PRKACA/DIAPH1	10
GO:1901184	regulation of ERBB signaling pathway	10/896	79/18722	0.00433067742173552	0.0203283874282008	NCF1/PLAUR/HBEGF/CCDC88A/PTPN18/SHKBP1/PTPN2/ADAM17/MVP/NUP62	10
GO:0032231	regulation of actin filament bundle assembly	12/896	105/18722	0.00438329057220394	0.020538283122552	PLEK/FLNA/WAS/CCDC88A/RHOA/GPR65/ARAP1/PAK1/PAK2/CDC42/ROCK1/PFN1	12
GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	12/896	105/18722	0.00438329057220394	0.020538283122552	ACTR2/RAC2/CCDC88A/DOCK11/ACTR3/ARAP1/CDC42EP3/RHOQ/TWF2/CDC42/PFN1/BRK1	12
GO:1905517	macrophage migration	8/896	55/18722	0.00440838710655001	0.0206372829353435	CCL3/C5AR1/CX3CR1/CCR2/CSF1R/PTK2B/CKLF/MAPK1	8
GO:0050435	amyloid-beta metabolic process	9/896	67/18722	0.0044737717971035	0.0209057386493578	SORL1/TNF/IFNGR1/PICALM/RTN3/ROCK1/ADAM10/SP1/PRNP	9
GO:1902117	positive regulation of organelle assembly	9/896	67/18722	0.0044737717971035	0.0209057386493578	LCP1/MSN/CCDC88A/TNF/RHOA/RALB/SDCBP/PIP4K2A/NUP62	9
GO:0021762	substantia nigra development	7/896	44/18722	0.00457191353971438	0.0213069196416259	ACTB/RHOA/MBP/CALM2/G6PD/CDC42/GNB4	7
GO:0042269	regulation of natural killer cell mediated cytotoxicity	7/896	44/18722	0.00457191353971438	0.0213069196416259	HLA-B/HLA-A/HLA-E/ARRB2/LILRB1/LGALS9/HLA-F	7
GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	7/896	44/18722	0.00457191353971438	0.0213069196416259	CYP1B1/JAK2/IL10RA/TNF/IL6R/CD300A/PTK2B	7
GO:0010820	positive regulation of T cell chemotaxis	4/896	15/18722	0.00465646438853267	0.0215849120185012	CCR2/ADAM10/ADAM17/WNK1	4
GO:0030852	regulation of granulocyte differentiation	4/896	15/18722	0.00465646438853267	0.0215849120185012	EVI2B/INPP5D/HCLS1/TRIB1	4
GO:0032486	Rap protein signal transduction	4/896	15/18722	0.00465646438853267	0.0215849120185012	TIMP2/RAP1A/RAP1B/RAP2B	4
GO:0042976	activation of Janus kinase activity	4/896	15/18722	0.00465646438853267	0.0215849120185012	JAK2/IL6R/CD300A/PTK2B	4
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	4/896	15/18722	0.00465646438853267	0.0215849120185012	ZFP36/ZFP36L2/PABPC1/ZFP36L1	4
GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	4/896	15/18722	0.00465646438853267	0.0215849120185012	TGFB1/TNF/STAT3/PPP3CA	4
GO:1903532	positive regulation of secretion by cell	24/896	282/18722	0.00469979914671033	0.0217663894586291	IL1B/ITGB2/FGR/HLA-DRB1/RETN/JAK2/HLA-F/TLR2/TGFB1/SYK/ITGAM/TLR4/CD33/RAB27A/PTAFR/SERP1/GLUL/NADK/RAB8B/SDCBP/HIF1A/ACSL4/IRS2/CREB1	24
GO:0071229	cellular response to acid chemical	10/896	80/18722	0.004742535710033	0.0219447760034534	CYBB/CYBA/KLF2/CEBPB/TNF/FYN/LAMTOR4/CAPN2/LAMTOR1/PLEC	10
GO:0051146	striated muscle cell differentiation	24/896	283/18722	0.00491011759825591	0.0226312042568438	RGS2/PLEKHO1/CD53/ARRB2/MEF2C/GPX1/TGFB1/SLC8A1/AKAP13/CAPN2/MEF2A/G6PD/PAK1/MTPN/PRKAR1A/KDM6B/CFLAR/RB1/FLII/YBX1/HNRNPU/MYH9/PPP3CA/PLEC	24
GO:0046456	icosanoid biosynthetic process	8/896	56/18722	0.00493236192830008	0.0226312042568438	IL1B/CD74/PTGS2/LTA4H/SYK/ALOX5/TBXAS1/ALOX5AP	8
GO:1990089	response to nerve growth factor	8/896	56/18722	0.00493236192830008	0.0226312042568438	CORO1A/ACAP2/ARPC3/RAP1A/PTEN/EEF2/CREB1/CIB1	8
GO:0006213	pyrimidine nucleoside metabolic process	5/896	24/18722	0.00493439446784481	0.0226312042568438	TYMP/APOBEC3A/DPYD/CDA/UPP1	5
GO:0038095	Fc-epsilon receptor signaling pathway	5/896	24/18722	0.00493439446784481	0.0226312042568438	FCER1G/LYN/MAP3K1/SYK/BTK	5
GO:0045649	regulation of macrophage differentiation	5/896	24/18722	0.00493439446784481	0.0226312042568438	TGFB1/HCLS1/TRIB1/RB1/PTPN2	5
GO:0050855	regulation of B cell receptor signaling pathway	5/896	24/18722	0.00493439446784481	0.0226312042568438	LYN/PRKCB/NFAM1/CD300A/CMTM3	5
GO:0051156	glucose 6-phosphate metabolic process	5/896	24/18722	0.00493439446784481	0.0226312042568438	TKT/G6PD/PGLS/PGD/TALDO1	5
GO:0090023	positive regulation of neutrophil chemotaxis	5/896	24/18722	0.00493439446784481	0.0226312042568438	CD74/C5AR1/CXCL8/RAC2/NCKAP1L	5
GO:1903428	positive regulation of reactive oxygen species biosynthetic process	5/896	24/18722	0.00493439446784481	0.0226312042568438	CYBA/SOD2/CD36/TLR4/RAB27A	5
GO:0032147	activation of protein kinase activity	14/896	134/18722	0.00495838863464858	0.0227212152324293	SLC11A1/JAK2/NCKAP1L/CD86/CCDC88A/IL6R/CD300A/PTK2B/OSBPL8/PRKAG2/TGFBR2/CAB39/PRNP/WNK1	14
GO:1901990	regulation of mitotic cell cycle phase transition	25/896	299/18722	0.00497099243859216	0.0227589187263361	AIF1/DUSP1/ZFP36L2/KLF4/PTPN6/BID/ZFP36L1/PSME2/PSME1/TAOK3/CDKN1A/KMT2E/PTEN/RB1/ATM/NABP1/FOXN3/TAOK1/WAC/LSM10/ADAM17/DDX3X/CTDSP1/ZNF207/DYNC1LI1	25
GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	6/896	34/18722	0.00503219261402739	0.0230188511746319	USP15/BIRC3/IRF7/IFIH1/SEC14L1/BIRC2	6
GO:0072659	protein localization to plasma membrane	24/896	284/18722	0.00512821510467819	0.0234374751840345	VAMP5/FLNA/ACTB/GBP1/MYADM/TGFB1/RILPL2/NUMB/PRAM1/CCDC88A/CSK/TNF/RHOG/RAB8B/RAP1A/PICALM/RHOQ/TNFRSF1A/ROCK1/TSPAN14/RAB10/PRNP/STX7/CIB1	24
GO:0048708	astrocyte differentiation	10/896	81/18722	0.00518454569608662	0.0236338004549394	S100A9/S100A8/VIM/C5AR1/GRN/TNF/TLR4/IFNGR1/STAT3/MAPK1	10
GO:0051817	modulation of process of other organism involved in symbiotic interaction	10/896	81/18722	0.00518454569608662	0.0236338004549394	CCL3/CX3CR1/CD4/CCL4/JUN/CFL1/CHD1/RXRA/SP1/EP300	10
GO:0016050	vesicle organization	25/896	300/18722	0.00518480413749007	0.0236338004549394	SRGN/ZEB2/CORO1A/LYST/SNX10/RAB32/STX11/SAMD9/RAB27A/STX10/BLOC1S1/RAB8B/CHP1/PICALM/SDCBP/PIP4K2A/CORO1C/LAMTOR1/GNAI3/CHMP1B/HOOK3/STX7/STX12/BLOC1S6/CREB1	25
GO:2000273	positive regulation of signaling receptor activity	7/896	45/18722	0.00519527575378479	0.0236607961431127	NCF1/IFNGR2/JAK2/CCR2/HBEGF/HIF1A/ADAM17	7
GO:0051702	biological process involved in interaction with symbiont	11/896	94/18722	0.00521684293069773	0.0237382327931399	CCL3/GPX1/CX3CR1/TREM1/MYD88/CCL4/JUN/CFL1/CHD1/SP1/EP300	11
GO:0043244	regulation of protein-containing complex disassembly	13/896	121/18722	0.00525748452013542	0.0239022526129583	PLEK/IRAK3/CAPG/TNF/SETX/CAPZA1/MTPN/CAPZA2/TWF2/FLII/CALCOCO2/TAOK1/CIB1	13
GO:0001101	response to acid chemical	14/896	135/18722	0.00529570074647822	0.0240549690676273	CYBB/CYBA/KLF2/LYN/CEBPB/TNF/RHOA/FYN/LAMTOR4/CAPN2/LAMTOR1/TMBIM6/PLEC/CREB1	14
GO:0006753	nucleoside phosphate metabolic process	37/896	497/18722	0.00535106171888891	0.0242852286212402	TYMP/TMSB4X/SAMHD1/NAMPT/LRRK2/DPYD/GIMAP7/PPT1/TGFB1/SULT1A1/CDA/UPP1/RHOA/PARP9/ENTPD1/KYNU/ACSL1/FBP1/NUDT16/PDK4/NADK/PRKAG2/RHOQ/ELOVL5/ATP6V1A/STAT3/ADCY7/HIF1A/PGK1/MAPK1/NUDT3/ACSL4/ZBTB7A/ADPGK/FAR1/GNAI3/EP300	37
GO:0042886	amide transport	25/896	301/18722	0.005406219997034	0.0245141675715552	S100A8/IL1B/CD74/HLA-DRB1/PSAP/JAK2/IL1RN/UCP2/TNF/TCIRG1/ALOX5/MGST1/TAP1/AQP9/SERP1/TAPBP/GLUL/MIDN/CYB5R4/NADK/RAB8B/HIF1A/ACSL4/IRS2/PPP3CA	25
GO:0006959	humoral immune response	26/896	317/18722	0.00543187372287041	0.0246090376591019	LYZ/FCN1/S100A9/IL1B/PTPRC/S100A12/HLA-A/CFD/POU2F2/CFP/SLC11A1/HLA-DRB1/HLA-E/CXCL8/HLA-DQB1/MEF2C/CD83/PTPN6/NOTCH2/RNASE6/CCR2/BST1/TREM1/TNF/ALOX5/PSMB10	26
GO:0010611	regulation of cardiac muscle hypertrophy	9/896	69/18722	0.00544881256840632	0.024621437157499	RGS2/TNFRSF1B/MEF2A/G6PD/PAK1/MTPN/TNFRSF1A/ROCK1/PPP3CA	9
GO:0050688	regulation of defense response to virus	9/896	69/18722	0.00544881256840632	0.024621437157499	FGL2/PYCARD/TNFAIP3/STAT1/LILRB1/PARP9/DTX3L/PCBP2/SEC14L1	9
GO:0050805	negative regulation of synaptic transmission	9/896	69/18722	0.00544881256840632	0.024621437157499	IL1B/LRRK2/GNAI2/PTGS2/LILRB2/PTK2B/RAP1A/PTEN/RAP1B	9
GO:0002011	morphogenesis of an epithelial sheet	8/896	57/18722	0.00550270215765964	0.0248218160641698	CD44/FLNA/NOTCH2/HBEGF/RHOA/ITGA5/PTEN/ADAM17	8
GO:1900024	regulation of substrate adhesion-dependent cell spreading	8/896	57/18722	0.00550270215765964	0.0248218160641698	FLNA/GBP1/MYADM/PREX1/CDC42/LIMS1/CORO1C/CIB1	8
GO:0099024	plasma membrane invagination	14/896	136/18722	0.00565124405186107	0.0254129136841643	AIF1/ITGB2/CD36/FCGR1A/RAC2/NCKAP1L/ITGAM/RHOA/CD300A/RHOG/CDC42/BIN2/MYH9/SNX18	14
GO:1900180	regulation of protein localization to nucleus	14/896	136/18722	0.00565124405186107	0.0254129136841643	FLNA/CD36/PTGS2/JAK2/TGFB1/PARP9/FYN/RASSF5/GLUL/HCLS1/DTX3L/CHP1/MAPK1/NUP62	14
GO:1903321	negative regulation of protein modification by small protein conjugation or removal	11/896	95/18722	0.00565195934193437	0.0254129136841643	TSPO/ISG15/TNFAIP3/ARRB2/FYN/HSPA1A/DTX3L/CHP1/SPOPL/IVNS1ABP/TRIP12	11
GO:0009205	purine ribonucleoside triphosphate metabolic process	10/896	82/18722	0.00565817228345747	0.0254129136841643	TMSB4X/LRRK2/GIMAP7/TGFB1/RHOA/PRKAG2/RHOQ/ATP6V1A/STAT3/GNAI3	10
GO:0043242	negative regulation of protein-containing complex disassembly	10/896	82/18722	0.00565817228345747	0.0254129136841643	IRAK3/CAPG/TNF/CAPZA1/MTPN/CAPZA2/TWF2/FLII/TAOK1/CIB1	10
GO:0034405	response to fluid shear stress	6/896	35/18722	0.00583231406478197	0.0261498840094233	KLF2/KLF4/PTGS2/MEF2C/PTK2B/PLEC	6
GO:0046627	negative regulation of insulin receptor signaling pathway	6/896	35/18722	0.00583231406478197	0.0261498840094233	IL1B/SOCS3/PTPRE/PRKCB/PIP4K2A/PTPN2	6
GO:0010001	glial cell differentiation	20/896	225/18722	0.00586094294180033	0.0262330156973352	S100A9/S100A8/VIM/TNFRSF1B/C5AR1/LYN/GRN/TLR2/TGFB1/CSK/CXCR4/TNF/RHOA/TLR4/IFNGR1/STAT3/PTEN/MAPK1/DICER1/PLEC	20
GO:0034284	response to monosaccharide	20/896	225/18722	0.00586094294180033	0.0262330156973352	CYBA/TXNIP/SOD2/LGALS1/NAMPT/EGR1/HLA-DRB1/PTGS2/UCP2/SLC8A1/RHOA/PTK2B/GLUL/NADK/PRKACA/PTEN/HIF1A/TGFBR2/IRS2/PPP3CA	20
GO:0045851	pH reduction	7/896	46/18722	0.00588030384657791	0.0262744504347523	SLC11A1/DMXL2/PPT1/GRN/TCIRG1/ATP6V0D1/ATP6AP2	7
GO:0061462	protein localization to lysosome	7/896	46/18722	0.00588030384657791	0.0262744504347523	LAPTM5/SORL1/LAMTOR4/MFSD1/NCOA4/M6PR/LAMP2	7
GO:0032878	regulation of establishment or maintenance of cell polarity	5/896	25/18722	0.00592901677725025	0.0262744844148771	PTK2B/SHTN1/DOCK8/ROCK1/RAP1B	5
GO:0046039	GTP metabolic process	5/896	25/18722	0.00592901677725025	0.0262744844148771	LRRK2/GIMAP7/RHOA/RHOQ/GNAI3	5
GO:0072012	glomerulus vasculature development	5/896	25/18722	0.00592901677725025	0.0262744844148771	EGR1/PECAM1/NOTCH2/IL6R/CFLAR	5
GO:1902993	positive regulation of amyloid precursor protein catabolic process	5/896	25/18722	0.00592901677725025	0.0262744844148771	LYN/TNF/IFNGR1/PICALM/SP1	5
GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA	5/896	25/18722	0.00592901677725025	0.0262744844148771	TGFB1/TNF/DDX5/STAT3/PPP3CA	5
GO:0006206	pyrimidine nucleobase metabolic process	4/896	16/18722	0.00597629591670825	0.0262744844148771	TYMP/DPYD/CDA/MAPK1	4
GO:0010819	regulation of T cell chemotaxis	4/896	16/18722	0.00597629591670825	0.0262744844148771	CCR2/ADAM10/ADAM17/WNK1	4
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	4/896	16/18722	0.00597629591670825	0.0262744844148771	IL1B/PRKCB/ITGA5/HIF1A	4
GO:0034138	toll-like receptor 3 signaling pathway	4/896	16/18722	0.00597629591670825	0.0262744844148771	TNFAIP3/SCIMP/OAS1/UNC93B1	4
GO:0035751	regulation of lysosomal lumen pH	4/896	16/18722	0.00597629591670825	0.0262744844148771	LRRK2/PPT1/GRN/ATP6AP2	4
GO:0043923	positive regulation by host of viral transcription	4/896	16/18722	0.00597629591670825	0.0262744844148771	JUN/CHD1/SP1/EP300	4
GO:0045342	MHC class II biosynthetic process	4/896	16/18722	0.00597629591670825	0.0262744844148771	SPI1/SLC11A1/JAK2/TLR4	4
GO:0045651	positive regulation of macrophage differentiation	4/896	16/18722	0.00597629591670825	0.0262744844148771	TGFB1/HCLS1/TRIB1/RB1	4
GO:0046135	pyrimidine nucleoside catabolic process	4/896	16/18722	0.00597629591670825	0.0262744844148771	APOBEC3A/DPYD/CDA/UPP1	4
GO:0051238	sequestering of metal ion	4/896	16/18722	0.00597629591670825	0.0262744844148771	S100A9/S100A8/FTL/FTH1	4
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	4/896	16/18722	0.00597629591670825	0.0262744844148771	NFKBIA/TNFAIP3/TLR4/HSPA1A	4
GO:0097284	hepatocyte apoptotic process	4/896	16/18722	0.00597629591670825	0.0262744844148771	BID/STK4/CFLAR/RB1	4
GO:1904683	regulation of metalloendopeptidase activity	4/896	16/18722	0.00597629591670825	0.0262744844148771	SORL1/MBP/PICALM/STAT3	4
GO:2001044	regulation of integrin-mediated signaling pathway	4/896	16/18722	0.00597629591670825	0.0262744844148771	TIMP1/FLNA/BST1/LIMS1	4
GO:0010811	positive regulation of cell-substrate adhesion	13/896	123/18722	0.00603239522088797	0.0264987225877013	FLNA/CD36/JAK2/IQGAP1/MYADM/PREX1/PTK2B/STK4/CDC42/RRAS/ROCK1/LIMS1/CIB1	13
GO:0010574	regulation of vascular endothelial growth factor production	8/896	58/18722	0.00612195689183324	0.0268467940931068	IL1B/C5AR1/PTGS2/CYP1B1/TGFB1/CCR2/SULF2/HIF1A	8
GO:0043506	regulation of JUN kinase activity	8/896	58/18722	0.00612195689183324	0.0268467940931068	SYK/TNF/FGD2/PTK2B/PAK1/TAOK3/HIPK3/MAP3K11	8
GO:0051480	regulation of cytosolic calcium ion concentration	28/896	353/18722	0.0063049579349954	0.0276260204043059	CYBA/PTPRC/CD52/CORO1A/FPR1/CCL3/C5AR1/LYN/CD36/PTPN6/JAK2/CX3CR1/CCR1/CCR2/SLC8A1/CXCR4/LPAR6/FYN/GPR65/PTK2B/FKBP1A/CALM2/PRKACA/DIAPH1/GNB1/TMBIM6/PRNP/GNA13	28
GO:0009408	response to heat	12/896	110/18722	0.00636426062404577	0.027838956691053	CD14/LYN/PTGS2/TFEC/HSPA1A/IER5/CDKN1A/PRKACA/ATM/HMOX1/CREBBP/EP300	12
GO:0014812	muscle cell migration	12/896	110/18722	0.00636426062404577	0.027838956691053	AIF1/PLEKHO1/MEF2C/IQGAP1/SORL1/RHOA/TLR4/TRIB1/PAK1/ROCK1/ARPC5/GNA13	12
GO:1903322	positive regulation of protein modification by small protein conjugation or removal	14/896	138/18722	0.00641979910058413	0.0280582984219647	LAPTM5/LRRK2/BIRC3/RASSF5/UBE2D1/FKBP1A/GABARAP/PTEN/TANK/PIAS1/MYCBP2/NMI/DDX3X/BIRC2	14
GO:0072503	cellular divalent inorganic cation homeostasis	36/896	486/18722	0.00643352442697893	0.0280946771995948	S100A9/S100A8/CYBA/PTPRC/CD52/CORO1A/FPR1/CCL3/C5AR1/SLC11A1/LYN/CD36/PTPN6/JAK2/CX3CR1/CCR1/PRKCB/CCR2/SLC8A1/CXCR4/TCIRG1/LPAR6/FYN/GPR65/PTK2B/FKBP1A/CALM2/PRKACA/DIAPH1/GNB1/MICU1/TMBIM6/PRNP/GRINA/GNA13/HERPUD1	36
GO:0042594	response to starvation	18/896	197/18722	0.00657359670652557	0.0286822789183217	ZFP36/LRRK2/IFI16/UCP2/UPP1/JUN/EIF4EBP1/GLUL/RALB/PDK4/GABARAP/PRKAG2/CDKN1A/KLF10/MAPK1/ATF3/MAX/LAMP2	18
GO:0016358	dendrite development	21/896	243/18722	0.00662896354631336	0.0288583111246999	LST1/LRRK2/ACTR2/MEF2C/IQGAP1/RHOA/PHACTR1/FYN/PREX1/MEF2A/CFL1/PICALM/PAK2/CDC42/PTEN/ADAM10/ACSL4/DBNL/PPP3CA/DYNLT1/ABI1	21
GO:0010761	fibroblast migration	7/896	47/18722	0.00663058677062418	0.0288583111246999	TGFB1/SLC8A1/ARHGAP4/PAK1/ZFAND5/CORO1C/PLEC	7
GO:0046677	response to antibiotic	7/896	47/18722	0.00663058677062418	0.0288583111246999	CRIP1/ACTR2/MEF2C/JAK2/JAK1/CYB5R4/KDM6B	7
GO:0050673	epithelial cell proliferation	33/896	437/18722	0.00670000417433497	0.0291360549420704	CYBA/ZFP36/JAML/B2M/C5AR1/TNFAIP3/STAT1/NR4A1/MEF2C/ITGA4/CEBPB/GPX1/GRN/TGFB1/NOTCH2/SULF2/TNF/STAT6/ALOX5/GPBAR1/ZFP36L1/GLUL/SERPINB1/CDC42/STAT3/CFLAR/PTEN/RB1/HIF1A/MAPK1/HMOX1/SP1/ADAM17	33
GO:0045445	myoblast differentiation	10/896	84/18722	0.00670624662245362	0.0291388376636435	LGALS1/MBNL1/MEF2C/TGFB1/TNF/ZFP36L1/BTG1/DDX5/RB1/PLEC	10
GO:0042092	type 2 immune response	6/896	36/18722	0.00672133076278552	0.029155664134485	CD74/CD86/NLRP3/CCR2/STAT6/BCL6	6
GO:0060251	regulation of glial cell proliferation	6/896	36/18722	0.00672133076278552	0.029155664134485	IL1B/TSPO/LYN/TNF/DICER1/CREB1	6
GO:0001836	release of cytochrome c from mitochondria	8/896	59/18722	0.00679270038562108	0.0293672773945264	PYCARD/SOD2/TNFSF10/ARRB2/PLAUR/GPX1/BID/JUN	8
GO:0030042	actin filament depolymerization	8/896	59/18722	0.00679270038562108	0.0293672773945264	PLEK/CAPG/CFL1/CAPZA1/MTPN/CAPZA2/TWF2/FLII	8
GO:0046324	regulation of glucose import	8/896	59/18722	0.00679270038562108	0.0293672773945264	TNF/OSBPL8/MEF2A/RAP1A/PRKAG2/RHOQ/IRS2/PEA15	8
GO:0051353	positive regulation of oxidoreductase activity	8/896	59/18722	0.00679270038562108	0.0293672773945264	IL1B/CYBA/GNAI2/TNF/GCH1/PTK2B/HIF1A/GNAI3	8
GO:1902806	regulation of cell cycle G1/S phase transition	16/896	168/18722	0.00684258587320088	0.0295583796731875	AIF1/KLF4/PTPN6/BID/PSME2/PSME1/CDKN1A/KMT2E/PTEN/RB1/ATM/WAC/LSM10/ADAM17/DDX3X/CTDSP1	16
GO:0002407	dendritic cell chemotaxis	5/896	26/18722	0.00705666425069729	0.03035708086673	SPI1/CCR1/LGALS9/CCR2/CXCR4	5
GO:0002710	negative regulation of T cell mediated immunity	5/896	26/18722	0.00705666425069729	0.03035708086673	PTPRC/LILRB1/HLA-F/NCKAP1L/AHR	5
GO:0070920	regulation of production of small RNA involved in gene silencing by RNA	5/896	26/18722	0.00705666425069729	0.03035708086673	TGFB1/TNF/DDX5/STAT3/PPP3CA	5
GO:0097066	response to thyroid hormone	5/896	26/18722	0.00705666425069729	0.03035708086673	CTSS/LMO2/CTSH/CTSB/CAB39	5
GO:1905523	positive regulation of macrophage migration	5/896	26/18722	0.00705666425069729	0.03035708086673	CCL3/C5AR1/CX3CR1/CSF1R/MAPK1	5
GO:0009117	nucleotide metabolic process	36/896	489/18722	0.00706622697720883	0.0303730962879861	TYMP/TMSB4X/SAMHD1/NAMPT/LRRK2/DPYD/GIMAP7/PPT1/TGFB1/SULT1A1/CDA/UPP1/RHOA/PARP9/KYNU/ACSL1/FBP1/NUDT16/PDK4/NADK/PRKAG2/RHOQ/ELOVL5/ATP6V1A/STAT3/ADCY7/HIF1A/PGK1/MAPK1/NUDT3/ACSL4/ZBTB7A/ADPGK/FAR1/GNAI3/EP300	36
GO:0043502	regulation of muscle adaptation	11/896	98/18722	0.00713066592680633	0.0305994995753463	AIF1/RGS2/TNFRSF1B/KLF4/MEF2A/G6PD/PAK1/MTPN/TNFRSF1A/ROCK1/PPP3CA	11
GO:1902882	regulation of response to oxidative stress	11/896	98/18722	0.00713066592680633	0.0305994995753463	SOD2/MCL1/LRRK2/CD36/GPX1/ALOX5/TLR4/MCTP1/FYN/GCH1/HIF1A	11
GO:0014743	regulation of muscle hypertrophy	9/896	72/18722	0.00720991335320414	0.0309140637675307	RGS2/TNFRSF1B/MEF2A/G6PD/PAK1/MTPN/TNFRSF1A/ROCK1/PPP3CA	9
GO:0009141	nucleoside triphosphate metabolic process	12/896	112/18722	0.00733109150257156	0.0314077486860582	TMSB4X/SAMHD1/LRRK2/GIMAP7/TGFB1/RHOA/NUDT16/PRKAG2/RHOQ/ATP6V1A/STAT3/GNAI3	12
GO:0002673	regulation of acute inflammatory response	7/896	48/18722	0.007449724143652	0.0318634994006037	IL1B/PTGS2/HLA-E/NLRP3/TNF/BTK/ALOX5AP	7
GO:0002715	regulation of natural killer cell mediated immunity	7/896	48/18722	0.007449724143652	0.0318634994006037	HLA-B/HLA-A/HLA-E/ARRB2/LILRB1/LGALS9/HLA-F	7
GO:0002712	regulation of B cell mediated immunity	8/896	60/18722	0.00751752559564446	0.0318894786824997	PTPRC/HLA-E/PTPN6/TGFB1/TNF/STAT6/BCL6/BTK	8
GO:0002889	regulation of immunoglobulin mediated immune response	8/896	60/18722	0.00751752559564446	0.0318894786824997	PTPRC/HLA-E/PTPN6/TGFB1/TNF/STAT6/BCL6/BTK	8
GO:0051851	modulation by host of symbiont process	8/896	60/18722	0.00751752559564446	0.0318894786824997	CCL3/CX3CR1/CCL4/JUN/CFL1/CHD1/SP1/EP300	8
GO:0032604	granulocyte macrophage colony-stimulating factor production	4/896	17/18722	0.00752324367302963	0.0318894786824997	IL1B/SYK/LILRA2/CD84	4
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	4/896	17/18722	0.00752324367302963	0.0318894786824997	IL1B/SYK/LILRA2/CD84	4
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	4/896	17/18722	0.00752324367302963	0.0318894786824997	SOCS3/SH2B3/PARP14/PTPN2	4
GO:0060263	regulation of respiratory burst	4/896	17/18722	0.00752324367302963	0.0318894786824997	NCF1/CLEC7A/RAC2/GRN	4
GO:0097067	cellular response to thyroid hormone stimulus	4/896	17/18722	0.00752324367302963	0.0318894786824997	CTSS/LMO2/CTSH/CTSB	4
GO:1900034	regulation of cellular response to heat	4/896	17/18722	0.00752324367302963	0.0318894786824997	IER5/ATM/CREBBP/EP300	4
GO:1901550	regulation of endothelial cell development	4/896	17/18722	0.00752324367302963	0.0318894786824997	IL1B/TNF/TNFRSF1A/ROCK1	4
GO:1903140	regulation of establishment of endothelial barrier	4/896	17/18722	0.00752324367302963	0.0318894786824997	IL1B/TNF/TNFRSF1A/ROCK1	4
GO:0002791	regulation of peptide secretion	18/896	200/18722	0.00765142282489242	0.0324063925995647	S100A8/IL1B/CD74/HLA-DRB1/JAK2/UCP2/TNF/TCIRG1/ALOX5/SERP1/GLUL/MIDN/NADK/RAB8B/HIF1A/ACSL4/IRS2/PPP3CA	18
GO:0000045	autophagosome assembly	11/896	99/18722	0.00768543273957999	0.0324202589265615	VMP1/LRRK2/TCIRG1/ATG16L2/RALB/GABARAP/C9orf72/ATG3/PIP4K2A/RB1CC1/STX12	11
GO:0009636	response to toxic substance	22/896	262/18722	0.00769874263617699	0.0324202589265615	S100A9/FOS/SOD2/CCL3/LYN/CD36/PTGS2/CYP1B1/GPX1/TLR2/MGST1/MBP/ALDH1A1/GCH1/CCL4/GLRX/AHR/ALOX5AP/CDKN1A/KDM6B/MAPK1/GSTK1	22
GO:0031330	negative regulation of cellular catabolic process	22/896	262/18722	0.00769874263617699	0.0324202589265615	TSPO/ZFP36/CST3/NAMPT/MCL1/TIMP1/LRRK2/SLC11A1/PABPC1/IL10RA/SORL1/MYD88/TIMP2/STAT3/ROCK1/SDCBP/HMOX1/YBX1/HNRNPU/CTSA/WAC/SMG1	22
GO:0006623	protein targeting to vacuole	6/896	37/18722	0.00770456451321478	0.0324202589265615	LAPTM5/VPS13C/SORL1/NCOA4/M6PR/LAMP2	6
GO:0032570	response to progesterone	6/896	37/18722	0.00770456451321478	0.0324202589265615	FOS/TXNIP/TSPO/FOSB/TLR2/TGFB1	6
GO:0072529	pyrimidine-containing compound catabolic process	6/896	37/18722	0.00770456451321478	0.0324202589265615	TYMP/APOBEC3A/DPYD/CDA/UPP1/TET2	6
GO:0090218	positive regulation of lipid kinase activity	6/896	37/18722	0.00770456451321478	0.0324202589265615	LYN/FGR/TGFB1/PTK2B/CDC42/DGKZ	6
GO:1900077	negative regulation of cellular response to insulin stimulus	6/896	37/18722	0.00770456451321478	0.0324202589265615	IL1B/SOCS3/PTPRE/PRKCB/PIP4K2A/PTPN2	6
GO:0009306	protein secretion	28/896	359/18722	0.00786183588741803	0.0330553019001303	IL1B/PLEK/HLA-DRB1/JAK2/IL1RN/UCP2/TLR2/TGFB1/TNF/TCIRG1/ALOX5/TLR4/CD33/SERP1/GLUL/MIDN/CYB5R4/NADK/RAB8B/HIF1A/RAB11FIP1/TMEM167A/ACSL4/M6PR/IRS2/PPP3CA/RAB10/BLOC1S6	28
GO:0002637	regulation of immunoglobulin production	9/896	73/18722	0.00788433007550946	0.0330963686220538	PTPRC/HLA-E/TGFB1/CD86/TNF/STAT6/BCL6/PKN1/TMBIM6	9
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	9/896	73/18722	0.00788433007550946	0.0330963686220538	NCF1/PLAUR/HBEGF/CCDC88A/SHKBP1/PTPN2/ADAM17/MVP/NUP62	9
GO:0034103	regulation of tissue remodeling	10/896	86/18722	0.00789889340428135	0.0331307617706994	CST3/TNFAIP3/TGFB1/SYK/CSF1R/CSK/INPP5D/PDK4/ROCK1/PPP3CA	10
GO:0071478	cellular response to radiation	17/896	186/18722	0.00809135007810092	0.0338560834724078	CYBA/CRIP1/CARD16/NAMPT/TIMP1/EGR1/IFI16/RHOB/PTGS2/GRB2/CDKN1A/POLK/TANK/NIPBL/ATM/CREBBP/EP300	17
GO:0120032	regulation of plasma membrane bounded cell projection assembly	17/896	186/18722	0.00809135007810092	0.0338560834724078	ACTR2/WAS/RAC2/CCDC88A/DOCK11/RHOG/ACTR3/ARAP1/CDC42EP3/RHOQ/TWF2/CDC42/ATG3/CYLD/PFN1/BRK1/CORO1C	17
GO:1902115	regulation of organelle assembly	17/896	186/18722	0.00809135007810092	0.0338560834724078	LCP1/LRRK2/MSN/HCK/CCDC88A/TNF/RHOA/HSPA1A/RALB/C9orf72/ATG3/SDCBP/CYLD/PIP4K2A/HNRNPU/CHMP1B/NUP62	17
GO:0006402	mRNA catabolic process	20/896	232/18722	0.00814237387356835	0.0340148486075735	ZFP36/VIM/ZFP36L2/SLC11A1/BTG2/PABPC1/MYD88/ZFP36L1/HSPA1A/NUDT16/DDX5/ROCK1/ATM/YBX1/HNRNPU/XRN2/CELF1/RNH1/XRN1/SMG1	20
GO:0010594	regulation of endothelial cell migration	20/896	232/18722	0.00814237387356835	0.0340148486075735	TMSB4X/KLF4/RHOB/PTGS2/MEF2C/GRN/TGFB1/TNF/RHOA/MAP3K3/PTK2B/GLUL/SP100/RRAS/HIF1A/PRCP/HMOX1/SP1/ADAM17/CIB1	20
GO:0035592	establishment of protein localization to extracellular region	28/896	360/18722	0.00814980450313987	0.0340185659878254	IL1B/PLEK/HLA-DRB1/JAK2/IL1RN/UCP2/TLR2/TGFB1/TNF/TCIRG1/ALOX5/TLR4/CD33/SERP1/GLUL/MIDN/CYB5R4/NADK/RAB8B/HIF1A/RAB11FIP1/TMEM167A/ACSL4/M6PR/IRS2/PPP3CA/RAB10/BLOC1S6	28
GO:0055074	calcium ion homeostasis	34/896	460/18722	0.00819552687981755	0.0341819850055582	CYBA/PTPRC/CD52/CORO1A/FPR1/CCL3/C5AR1/LYN/CD36/SNX10/PTPN6/JAK2/CX3CR1/CCR1/PRKCB/CCR2/SLC8A1/CXCR4/TCIRG1/LPAR6/FYN/GPR65/PTK2B/FKBP1A/CALM2/PRKACA/DIAPH1/GNB1/MICU1/TMBIM6/PRNP/GRINA/GNA13/HERPUD1	34
GO:0097553	calcium ion transmembrane import into cytosol	14/896	142/18722	0.0082067944026407	0.034201552634723	CYBA/PTPRC/CORO1A/CCL3/LYN/PTPN6/SLC8A1/FYN/PTK2B/FKBP1A/CALM2/PRKACA/DIAPH1/PRNP	14
GO:0110020	regulation of actomyosin structure organization	11/896	100/18722	0.00827320714127909	0.0344310912800803	WAS/CCDC88A/RHOA/GPR65/AKAP13/ARAP1/PAK1/PAK2/CDC42/ROCK1/PFN1	11
GO:0031954	positive regulation of protein autophosphorylation	5/896	27/18722	0.00832582694199448	0.0344310912800803	IQGAP1/RASSF2/CALM2/RAP2B/DDX3X	5
GO:0034143	regulation of toll-like receptor 4 signaling pathway	5/896	27/18722	0.00832582694199448	0.0344310912800803	LYN/TNFAIP3/LILRA2/IFI35/NINJ1	5
GO:0060142	regulation of syncytium formation by plasma membrane fusion	5/896	27/18722	0.00832582694199448	0.0344310912800803	TYROBP/PLEKHO1/CD53/CAPN2/CFLAR	5
GO:0061437	renal system vasculature development	5/896	27/18722	0.00832582694199448	0.0344310912800803	EGR1/PECAM1/NOTCH2/IL6R/CFLAR	5
GO:0061440	kidney vasculature development	5/896	27/18722	0.00832582694199448	0.0344310912800803	EGR1/PECAM1/NOTCH2/IL6R/CFLAR	5
GO:0071624	positive regulation of granulocyte chemotaxis	5/896	27/18722	0.00832582694199448	0.0344310912800803	CD74/C5AR1/CXCL8/RAC2/NCKAP1L	5
GO:0009409	response to cold	7/896	49/18722	0.00834131417283238	0.0344310912800803	FOS/SOD2/NFKBIA/PLAC8/UCP2/METRNL/PRKACA	7
GO:0060964	regulation of gene silencing by miRNA	7/896	49/18722	0.00834131417283238	0.0344310912800803	ZFP36/NEAT1/TGFB1/TNF/DDX5/STAT3/PPP3CA	7
GO:0070849	response to epidermal growth factor	7/896	49/18722	0.00834131417283238	0.0344310912800803	ZFP36/ZFP36L2/IQGAP1/ZFP36L1/CFLAR/MAPK1/DUSP22	7
GO:0072666	establishment of protein localization to vacuole	7/896	49/18722	0.00834131417283238	0.0344310912800803	LAPTM5/TNFAIP3/VPS13C/SORL1/NCOA4/M6PR/LAMP2	7
GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	7/896	49/18722	0.00834131417283238	0.0344310912800803	GNAI2/JAK2/TNF/JUN/PAK1/NQO2/GNAI3	7
GO:0001952	regulation of cell-matrix adhesion	13/896	128/18722	0.00837119049566215	0.0345270117112917	CD36/IQGAP1/BST1/RHOA/BCL6/PTK2B/RRAS/ROCK1/PTEN/LIMS1/CORO1C/DUSP22/CIB1	13
GO:0090087	regulation of peptide transport	18/896	202/18722	0.00844610296840586	0.0348083847374635	S100A8/IL1B/CD74/HLA-DRB1/JAK2/UCP2/TNF/TCIRG1/ALOX5/SERP1/GLUL/MIDN/NADK/RAB8B/HIF1A/ACSL4/IRS2/PPP3CA	18
GO:0007160	cell-matrix adhesion	20/896	233/18722	0.00852022590998841	0.0350860609325809	ITGB2/CD44/CD36/ITGA4/IQGAP1/ZYX/ITGAL/FERMT3/PARVG/BST1/RHOA/BCL6/PTK2B/RRAS/ROCK1/PTEN/LIMS1/CORO1C/DUSP22/CIB1	20
GO:0046323	glucose import	9/896	74/18722	0.00860572677401329	0.0354101146769328	SLC2A3/TNF/OSBPL8/MEF2A/RAP1A/PRKAG2/RHOQ/IRS2/PEA15	9
GO:0045926	negative regulation of growth	21/896	249/18722	0.00865986933216909	0.0356047275862541	RGS2/BST2/PLAC8/PPT1/TGFB1/NOTCH2/CDA/BCL6/ARHGAP4/FBP1/HSPA1A/STK4/G6PD/BTG1/PAK1/CDKN1A/PTEN/RB1/HIF1A/TGFBR2/DDX3X	21
GO:0010742	macrophage derived foam cell differentiation	6/896	38/18722	0.00878727766846783	0.0359863237430718	NFKBIA/CD36/STAT1/TGFB1/EP300/NFKB1	6
GO:0030279	negative regulation of ossification	6/896	38/18722	0.00878727766846783	0.0359863237430718	SRGN/CCL3/MEF2C/CCR1/PTK2B/HIF1A	6
GO:0048246	macrophage chemotaxis	6/896	38/18722	0.00878727766846783	0.0359863237430718	CCL3/C5AR1/CSF1R/PTK2B/CKLF/MAPK1	6
GO:0090077	foam cell differentiation	6/896	38/18722	0.00878727766846783	0.0359863237430718	NFKBIA/CD36/STAT1/TGFB1/EP300/NFKB1	6
GO:0098926	postsynaptic signal transduction	6/896	38/18722	0.00878727766846783	0.0359863237430718	GNAI2/JAK2/RGS10/STAT3/GNAQ/GNB1	6
GO:0150115	cell-substrate junction organization	11/896	101/18722	0.00889525242600426	0.0363998488337122	IQGAP1/RHOA/PTK2B/RAB8B/TLN1/ROCK1/PTEN/LIMS1/CORO1C/DUSP22/PLEC	11
GO:0060491	regulation of cell projection assembly	17/896	188/18722	0.00896060221609627	0.0366384372059094	ACTR2/WAS/RAC2/CCDC88A/DOCK11/RHOG/ACTR3/ARAP1/CDC42EP3/RHOQ/TWF2/CDC42/ATG3/CYLD/PFN1/BRK1/CORO1C	17
GO:0051099	positive regulation of binding	16/896	173/18722	0.00897905526555881	0.0366850482609359	B2M/LRRK2/KLF4/PLAUR/JAK2/TGFB1/PARP9/FKBP1A/CALM2/RALB/STK4/DTX3L/RB1/CTBP2/MBD2/EP300	16
GO:0051209	release of sequestered calcium ion into cytosol	12/896	115/18722	0.00899352221055848	0.036715313200247	CYBA/PTPRC/CORO1A/CCL3/LYN/PTPN6/SLC8A1/PTK2B/FKBP1A/CALM2/PRKACA/DIAPH1	12
GO:0009746	response to hexose	19/896	219/18722	0.00913118178564369	0.0371958876282404	CYBA/TXNIP/LGALS1/NAMPT/EGR1/HLA-DRB1/PTGS2/UCP2/SLC8A1/RHOA/PTK2B/GLUL/NADK/PRKACA/PTEN/HIF1A/TGFBR2/IRS2/PPP3CA	19
GO:0034764	positive regulation of transmembrane transport	19/896	219/18722	0.00913118178564369	0.0371958876282404	CTSS/TMSB4X/VMP1/FLNA/IFNGR2/CCR2/KCNE3/PTAFR/ACSL1/GLRX/OSBPL8/CALM2/MEF2A/G6PD/CHP1/RAP1A/RHOQ/IRS2/WNK1	19
GO:0032835	glomerulus development	8/896	62/18722	0.00913984702728153	0.0371958876282404	EGR1/MEF2C/PECAM1/IQGAP1/NOTCH2/SULF2/IL6R/CFLAR	8
GO:0046824	positive regulation of nucleocytoplasmic transport	8/896	62/18722	0.00913984702728153	0.0371958876282404	IL1B/FLNA/PTGS2/JAK2/TGFB1/HCLS1/PRKACA/MAPK1	8
GO:0010324	membrane invagination	14/896	144/18722	0.00923700893950035	0.0375619104725108	AIF1/ITGB2/CD36/FCGR1A/RAC2/NCKAP1L/ITGAM/RHOA/CD300A/RHOG/CDC42/BIN2/MYH9/SNX18	14
GO:0002295	T-helper cell lineage commitment	4/896	18/18722	0.00931210175725844	0.0376318890749815	STAT6/IL6R/SPN/STAT3	4
GO:0002544	chronic inflammatory response	4/896	18/18722	0.00931210175725844	0.0376318890749815	S100A9/S100A8/TNFAIP3/TNF	4
GO:0002643	regulation of tolerance induction	4/896	18/18722	0.00931210175725844	0.0376318890749815	HLA-B/LILRB2/IRAK3/TGFBR2	4
GO:0050665	hydrogen peroxide biosynthetic process	4/896	18/18722	0.00931210175725844	0.0376318890749815	CYBA/SOD2/FYN/STAT3	4
GO:0080182	histone H3-K4 trimethylation	4/896	18/18722	0.00931210175725844	0.0376318890749815	KMT2E/ARID4A/TET2/KMT2A	4
GO:0150078	positive regulation of neuroinflammatory response	4/896	18/18722	0.00931210175725844	0.0376318890749815	IL1B/CCL3/LRRK2/TNF	4
GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	4/896	18/18722	0.00931210175725844	0.0376318890749815	ZFP36/ZFP36L2/PABPC1/ZFP36L1	4
GO:1902683	regulation of receptor localization to synapse	4/896	18/18722	0.00931210175725844	0.0376318890749815	TYROBP/RAP1A/ADAM10/STX7	4
GO:0007584	response to nutrient	16/896	174/18722	0.00946403073212043	0.0382161675758993	CYBB/TSPO/SOD2/GNAI2/PTGS2/STAT1/SLC8A1/APAF1/KYNU/ACSL1/PTEN/ACSL4/HMOX1/TGFBR2/EEF2/USF2	16
GO:0050678	regulation of epithelial cell proliferation	29/896	381/18722	0.00953808751466067	0.0384853321673779	CYBA/ZFP36/JAML/B2M/C5AR1/TNFAIP3/STAT1/NR4A1/MEF2C/ITGA4/GPX1/GRN/TGFB1/NOTCH2/SULF2/TNF/ALOX5/GPBAR1/ZFP36L1/GLUL/CDC42/STAT3/CFLAR/PTEN/RB1/HIF1A/HMOX1/SP1/ADAM17	29
GO:0006874	cellular calcium ion homeostasis	33/896	448/18722	0.00954644730615102	0.0384892034413112	CYBA/PTPRC/CD52/CORO1A/FPR1/CCL3/C5AR1/LYN/CD36/PTPN6/JAK2/CX3CR1/CCR1/PRKCB/CCR2/SLC8A1/CXCR4/TCIRG1/LPAR6/FYN/GPR65/PTK2B/FKBP1A/CALM2/PRKACA/DIAPH1/GNB1/MICU1/TMBIM6/PRNP/GRINA/GNA13/HERPUD1	33
GO:0043200	response to amino acid	12/896	116/18722	0.00960842143719973	0.0386791020858172	CYBB/CYBA/LYN/CEBPB/TNF/RHOA/FYN/LAMTOR4/CAPN2/LAMTOR1/TMBIM6/CREB1	12
GO:0051283	negative regulation of sequestering of calcium ion	12/896	116/18722	0.00960842143719973	0.0386791020858172	CYBA/PTPRC/CORO1A/CCL3/LYN/PTPN6/SLC8A1/PTK2B/FKBP1A/CALM2/PRKACA/DIAPH1	12
GO:0048738	cardiac muscle tissue development	20/896	236/18722	0.00973959026273878	0.0390764959660504	RGS2/ARRB2/MEF2C/TGFB1/NOTCH2/SLC8A1/AKAP13/FKBP1A/MEF2A/G6PD/PAK1/CDC42/PRKAR1A/KDM6B/PTEN/MAPK1/TGFBR2/HNRNPU/PLEC/CREB1	20
GO:0032438	melanosome organization	5/896	28/18722	0.009744705877325	0.0390764959660504	ZEB2/LYST/RAB32/BLOC1S1/BLOC1S6	5
GO:0070076	histone lysine demethylation	5/896	28/18722	0.009744705877325	0.0390764959660504	KDM1B/JMJD1C/KDM6B/KDM7A/KDM5A	5
GO:0090344	negative regulation of cell aging	5/896	28/18722	0.009744705877325	0.0390764959660504	NAMPT/BCL6/MAP3K3/PTEN/YBX1	5
GO:1902624	positive regulation of neutrophil migration	5/896	28/18722	0.009744705877325	0.0390764959660504	CD74/C5AR1/CXCL8/RAC2/NCKAP1L	5
GO:0060348	bone development	18/896	205/18722	0.0097612281582622	0.0391125944923896	TYROBP/PTPRC/SNX10/MEF2C/PTPN6/LILRB1/NOTCH2/SULF2/RHOA/FLI1/SH2B3/AKAP13/ZNF385A/PIP4K2A/TGFBR2/ABI1/FOXN3/EP300	18
GO:0061351	neural precursor cell proliferation	14/896	145/18722	0.00978893611507529	0.0391934231982345	C5AR1/LRRK2/LYN/FLNA/BTG2/GNAI2/CX3CR1/CTSZ/NUMB/RHOA/HIF1A/PLXNB2/RAB10/HOOK3	14
GO:0060402	calcium ion transport into cytosol	15/896	160/18722	0.00994011398268044	0.0397681021722469	CYBA/PTPRC/CORO1A/CCL3/LYN/PTPN6/SLC8A1/FYN/PTK2B/FKBP1A/CALM2/PRKACA/DIAPH1/TMBIM6/PRNP	15
GO:0032506	cytokinetic process	6/896	39/18722	0.00997464965359487	0.0397684823821851	RHOA/MYH9/PLEC/CHMP1B/NUP62/SNX18	6
GO:0045622	regulation of T-helper cell differentiation	6/896	39/18722	0.00997464965359487	0.0397684823821851	HLA-DRA/NFKBIZ/HLA-DRB1/CD86/NLRP3/BCL6	6
GO:0045923	positive regulation of fatty acid metabolic process	6/896	39/18722	0.00997464965359487	0.0397684823821851	IL1B/CD74/PTGS2/LPGAT1/ELOVL5/IRS2	6
GO:0046621	negative regulation of organ growth	6/896	39/18722	0.00997464965359487	0.0397684823821851	RGS2/STK4/G6PD/PAK1/PTEN/TGFBR2	6
GO:0009199	ribonucleoside triphosphate metabolic process	10/896	89/18722	0.00998608690465943	0.0397684823821851	TMSB4X/LRRK2/GIMAP7/TGFB1/RHOA/PRKAG2/RHOQ/ATP6V1A/STAT3/GNAI3	10
GO:1900407	regulation of cellular response to oxidative stress	10/896	89/18722	0.00998608690465943	0.0397684823821851	SOD2/MCL1/LRRK2/CD36/GPX1/ALOX5/TLR4/FYN/GCH1/HIF1A	10
GO:0032233	positive regulation of actin filament bundle assembly	8/896	63/18722	0.0100425632140454	0.0399322410368885	PLEK/FLNA/CCDC88A/RHOA/GPR65/PAK1/CDC42/PFN1	8
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	8/896	63/18722	0.0100425632140454	0.0399322410368885	LRRK2/CEBPB/HSPA1A/PPP1R15A/PTPN2/TMBIM6/GRINA/HERPUD1	8
GO:0006612	protein targeting to membrane	13/896	131/18722	0.0100842854509025	0.0400369226184306	ITGB2/NCF1/ITGAM/FYN/RAB8B/CHP1/PAK1/ATG3/SDCBP/ZDHHC20/SSR1/PRNP/CIB1	13
GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	13/896	131/18722	0.0100842854509025	0.0400369226184306	ZEB2/TGFB1/C20orf27/HSPA1A/FKBP1A/SKIL/CFLAR/SDCBP/ZBTB7A/ADAM17/CREBBP/EP300/FAM89B	13
GO:0061564	axon development	34/896	467/18722	0.0101712588552498	0.0400882798446268	TSPO/S100A6/FLNA/KLF4/ACTB/RAC2/ITGA4/NR4A2/JAK2/GRN/VASP/NOTCH2/NUMB/PLXNC1/FYN/ARHGAP4/RHOG/DPYSL2/SKIL/NIN/C9orf72/SHTN1/PICALM/PAK1/PAK2/TWF2/PTEN/PLXNB2/DBNL/MYCBP2/RAB10/DYNLT1/EMB/CREB1	34
GO:0001915	negative regulation of T cell mediated cytotoxicity	3/896	10/18722	0.0101796437172739	0.0400882798446268	PTPRC/LILRB1/NCKAP1L	3
GO:0010728	regulation of hydrogen peroxide biosynthetic process	3/896	10/18722	0.0101796437172739	0.0400882798446268	SOD2/FYN/STAT3	3
GO:0015911	long-chain fatty acid import across plasma membrane	3/896	10/18722	0.0101796437172739	0.0400882798446268	CD36/ACSL1/IRS2	3
GO:0042989	sequestering of actin monomers	3/896	10/18722	0.0101796437172739	0.0400882798446268	TMSB4X/TMSB10/TWF2	3
GO:0044351	macropinocytosis	3/896	10/18722	0.0101796437172739	0.0400882798446268	PYCARD/DOCK2/MAPKAPK3	3
GO:0050861	positive regulation of B cell receptor signaling pathway	3/896	10/18722	0.0101796437172739	0.0400882798446268	PRKCB/NFAM1/CMTM3	3
GO:0072124	regulation of glomerular mesangial cell proliferation	3/896	10/18722	0.0101796437172739	0.0400882798446268	EGR1/IL6R/CFLAR	3
GO:1902946	protein localization to early endosome	3/896	10/18722	0.0101796437172739	0.0400882798446268	MSN/SORL1/DTX3L	3
GO:1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	3/896	10/18722	0.0101796437172739	0.0400882798446268	LYN/SORL1/PICALM	3
GO:0031100	animal organ regeneration	9/896	76/18722	0.0101974224638418	0.0400882798446268	LCP1/C5AR1/CEBPB/UCP2/SULF2/RAP1A/CDKN1A/HMOX1/TGFBR2	9
GO:0043536	positive regulation of blood vessel endothelial cell migration	9/896	76/18722	0.0101974224638418	0.0400882798446268	TMSB4X/PTGS2/TGFB1/MAP3K3/HIF1A/HMOX1/SP1/ADAM17/CIB1	9
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	9/896	76/18722	0.0101974224638418	0.0400882798446268	CD74/PYCARD/CD44/IFI16/CDKN1A/DDX5/ZNF385A/HIPK1/EP300	9
GO:1905037	autophagosome organization	11/896	103/18722	0.0102472557039313	0.0402537590001107	VMP1/LRRK2/TCIRG1/ATG16L2/RALB/GABARAP/C9orf72/ATG3/PIP4K2A/RB1CC1/STX12	11
GO:1903307	positive regulation of regulated secretory pathway	7/896	51/18722	0.0103561658899969	0.0406508821085841	ITGB2/FGR/HLA-F/SYK/ITGAM/RAB27A/PTAFR	7
GO:0001701	in utero embryonic development	28/896	367/18722	0.0104180294397878	0.0408628741450501	JUNB/KLF2/KLF4/SOCS3/MBNL1/CEBPB/SCO2/NOTCH2/LPAR6/ZFP36L1/PTPN18/CAPN2/CMTM3/STK4/SKIL/GRB2/ZFAND5/MGAT1/HIF1A/ADAM10/MAPK1/YBX1/BRK1/SMIM14/TGFBR2/MYH9/WDR74/SP3	28
GO:0042692	muscle cell differentiation	29/896	384/18722	0.0105538757126713	0.0413645121187669	RGS2/SOD2/PLEKHO1/CD53/ARRB2/MEF2C/GPX1/TGFB1/SLC8A1/AKAP13/CAPN2/MEF2A/G6PD/PAK1/MTPN/PRKAR1A/KDM6B/CFLAR/RB1/PIAS1/FLII/YBX1/HNRNPU/MYH9/PPP3CA/QKI/PLEC/NINJ1/EPC1	29
GO:0051259	protein complex oligomerization	20/896	238/18722	0.0106277282195622	0.0416226012574874	SAMHD1/CD74/PYCARD/SOD2/B2M/KCTD12/ISG15/HLA-DRB1/RNF213/VASP/GBP5/SHKBP1/STK4/ALOX5AP/CHP1/OXA1L/MICU1/PRNP/NINJ1/MAT2A	20
GO:0099175	regulation of postsynapse organization	10/896	90/18722	0.0107676331236957	0.0421387959942374	SRGN/LRRK2/LILRB2/ACTR2/FYN/CFL1/PTEN/ADAM10/DBNL/PRNP	10
GO:0071692	protein localization to extracellular region	28/896	368/18722	0.0107804657484709	0.0421572950058626	IL1B/PLEK/HLA-DRB1/JAK2/IL1RN/UCP2/TLR2/TGFB1/TNF/TCIRG1/ALOX5/TLR4/CD33/SERP1/GLUL/MIDN/CYB5R4/NADK/RAB8B/HIF1A/RAB11FIP1/TMEM167A/ACSL4/M6PR/IRS2/PPP3CA/RAB10/BLOC1S6	28
GO:0009259	ribonucleotide metabolic process	29/896	385/18722	0.0109114665717161	0.0426055087383598	TMSB4X/LRRK2/DPYD/GIMAP7/PPT1/TGFB1/SULT1A1/UPP1/RHOA/KYNU/ACSL1/FBP1/NUDT16/PDK4/PRKAG2/RHOQ/ELOVL5/ATP6V1A/STAT3/ADCY7/HIF1A/PGK1/NUDT3/ACSL4/ZBTB7A/ADPGK/FAR1/GNAI3/EP300	29
GO:0045786	negative regulation of cell cycle	29/896	385/18722	0.0109114665717161	0.0426055087383598	DUSP1/ZFP36L2/KLF4/BTG2/RHOB/PTGS2/TNFAIP3/NR4A1/LILRB1/TGFB1/TNF/HHEX/BCL6/ZFP36L1/TIMP2/BTG1/TAOK3/CDKN1A/PRKAR1A/PTEN/RB1/ATM/NABP1/FOXN3/TAOK1/WAC/CTDSP1/ZNF207/DYNC1LI1	29
GO:0051282	regulation of sequestering of calcium ion	12/896	118/18722	0.0109357169399707	0.0426681648948146	CYBA/PTPRC/CORO1A/CCL3/LYN/PTPN6/SLC8A1/PTK2B/FKBP1A/CALM2/PRKACA/DIAPH1	12
GO:0014896	muscle hypertrophy	11/896	104/18722	0.010979781887387	0.0428079802071212	CYBA/RGS2/TNFRSF1B/AKAP13/MEF2A/G6PD/PAK1/MTPN/TNFRSF1A/ROCK1/PPP3CA	11
GO:0071466	cellular response to xenobiotic stimulus	16/896	177/18722	0.0110447448687575	0.0430290022939385	IL1B/APOBEC3A/S100A12/CYP1B1/MEF2C/RNF149/SULT1A1/CXCR4/ACSL1/FBP1/AHR/RAP1A/RB1/RAP1B/PPP1R12A/PRNP	16
GO:0002714	positive regulation of B cell mediated immunity	6/896	40/18722	0.0112717544130699	0.0438149437237493	PTPRC/HLA-E/TGFB1/TNF/STAT6/BTK	6
GO:0002891	positive regulation of immunoglobulin mediated immune response	6/896	40/18722	0.0112717544130699	0.0438149437237493	PTPRC/HLA-E/TGFB1/TNF/STAT6/BTK	6
GO:0070266	necroptotic process	6/896	40/18722	0.0112717544130699	0.0438149437237493	TNF/BIRC3/CFLAR/CYLD/PYGL/BIRC2	6
GO:0002360	T cell lineage commitment	5/896	29/18722	0.0113211663441399	0.0438488625174354	STAT6/RHOA/IL6R/SPN/STAT3	5
GO:0048753	pigment granule organization	5/896	29/18722	0.0113211663441399	0.0438488625174354	ZEB2/LYST/RAB32/BLOC1S1/BLOC1S6	5
GO:0062098	regulation of programmed necrotic cell death	5/896	29/18722	0.0113211663441399	0.0438488625174354	BIRC3/CFLAR/CYLD/ASAH1/BIRC2	5
GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	4/896	19/18722	0.0113563579717334	0.0438488625174354	GNAI2/RGS10/GNAQ/GNB1	4
GO:0010829	negative regulation of glucose transmembrane transport	4/896	19/18722	0.0113563579717334	0.0438488625174354	IL1B/PRKCB/TNF/PEA15	4
GO:0035313	wound healing, spreading of epidermal cells	4/896	19/18722	0.0113563579717334	0.0438488625174354	HBEGF/ITGA5/PTEN/ADAM17	4
GO:0070262	peptidyl-serine dephosphorylation	4/896	19/18722	0.0113563579717334	0.0438488625174354	DUSP1/PPP1R15A/PPP1R15B/PPP3CA	4
GO:1901739	regulation of myoblast fusion	4/896	19/18722	0.0113563579717334	0.0438488625174354	PLEKHO1/CD53/CAPN2/CFLAR	4
GO:1903978	regulation of microglial cell activation	4/896	19/18722	0.0113563579717334	0.0438488625174354	PTPRC/CCL3/LRRK2/GRN	4
GO:0010595	positive regulation of endothelial cell migration	13/896	133/18722	0.0113702550812724	0.0438699530249982	TMSB4X/RHOB/PTGS2/GRN/TGFB1/MAP3K3/PTK2B/RRAS/HIF1A/HMOX1/SP1/ADAM17/CIB1	13
GO:0043277	apoptotic cell clearance	7/896	52/18722	0.0114865092484897	0.0442528404454777	FCN1/TYROBP/CD36/RAC2/CCR2/CD300LF/RHOG	7
GO:0043392	negative regulation of DNA binding	7/896	52/18722	0.0114865092484897	0.0442528404454777	TMSB4X/NFKBIA/IFI16/JAK2/JUN/SP100/HMOX1	7
GO:0051492	regulation of stress fiber assembly	10/896	91/18722	0.0115947238638213	0.0446366830612395	WAS/CCDC88A/RHOA/GPR65/ARAP1/PAK1/PAK2/CDC42/ROCK1/PFN1	10
GO:0051962	positive regulation of nervous system development	22/896	272/18722	0.0116343876529976	0.0447562501355329	IL1B/TSPO/TNFRSF1B/LYN/ACTR2/CX3CR1/TLR2/TGFB1/NUMB/CXCR4/PLXNC1/TNF/SKIL/NIN/SHTN1/PAK1/TWF2/HIF1A/PLXNB2/DBNL/SPEN/DICER1	22
GO:0031398	positive regulation of protein ubiquitination	12/896	119/18722	0.0116502568922244	0.0447841730202951	LAPTM5/LRRK2/BIRC3/RASSF5/UBE2D1/FKBP1A/GABARAP/PTEN/MYCBP2/NMI/DDX3X/BIRC2	12
GO:0070613	regulation of protein processing	8/896	65/18722	0.0120441071365396	0.046229816396415	CARD16/LRRK2/CTSZ/PRKACA/CAST/CARD8/MYH9/PRNP	8
GO:0070936	protein K48-linked ubiquitination	8/896	65/18722	0.0120441071365396	0.046229816396415	TNFAIP3/UBE2D1/DTX3L/GABARAP/UBE2D3/UBE2R2/NMI/BIRC2	8
GO:1901991	negative regulation of mitotic cell cycle phase transition	16/896	179/18722	0.0122093067382234	0.0468293542370943	DUSP1/ZFP36L2/KLF4/ZFP36L1/TAOK3/CDKN1A/PTEN/RB1/ATM/NABP1/FOXN3/TAOK1/WAC/CTDSP1/ZNF207/DYNC1LI1	16
GO:0050806	positive regulation of synaptic transmission	15/896	164/18722	0.0122980357692068	0.0471349182281831	TYROBP/PTGS2/LILRB2/ARRB2/RETN/CX3CR1/CCR2/TNF/NRGN/PTK2B/GLUL/PTEN/MAPK1/PRNP/CREB1	15
GO:0034765	regulation of ion transmembrane transport	35/896	491/18722	0.0124679462959271	0.0477509489581125	CTSS/CYBB/CYBA/TMSB4X/RGS2/VMP1/CORO1A/LYN/FLNA/FXYD5/MEF2C/IFNGR2/PTPN6/CCR2/SLC8A1/KCNE3/TCIRG1/PTAFR/FYN/HVCN1/PTK2B/GLRX/FKBP1A/AHNAK/CALM2/G6PD/CHP1/PRKACA/DIAPH1/CLIC1/PTEN/SLC31A2/CAB39/PRNP/WNK1	35
GO:0002790	peptide secretion	20/896	242/18722	0.0125982517808493	0.048207507218794	S100A8/IL1B/CD74/HLA-DRB1/JAK2/IL1RN/UCP2/TNF/TCIRG1/ALOX5/SERP1/GLUL/MIDN/CYB5R4/NADK/RAB8B/HIF1A/ACSL4/IRS2/PPP3CA	20
GO:0030073	insulin secretion	17/896	195/18722	0.0126056931008575	0.048207507218794	IL1B/HLA-DRB1/JAK2/IL1RN/UCP2/TNF/TCIRG1/ALOX5/SERP1/GLUL/MIDN/CYB5R4/NADK/HIF1A/ACSL4/IRS2/PPP3CA	17
GO:0042307	positive regulation of protein import into nucleus	6/896	41/18722	0.0126835388889186	0.0482619569669909	FLNA/PTGS2/JAK2/TGFB1/HCLS1/MAPK1	6
GO:0050691	regulation of defense response to virus by host	6/896	41/18722	0.0126835388889186	0.0482619569669909	PYCARD/TNFAIP3/STAT1/LILRB1/PARP9/DTX3L	6
GO:0051693	actin filament capping	6/896	41/18722	0.0126835388889186	0.0482619569669909	CAPG/CAPZA1/MTPN/CAPZA2/TWF2/FLII	6
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	6/896	41/18722	0.0126835388889186	0.0482619569669909	FLNA/MYADM/PREX1/CDC42/LIMS1/CIB1	6
GO:1905314	semi-lunar valve development	6/896	41/18722	0.0126835388889186	0.0482619569669909	TNFRSF1B/TGFB1/NOTCH2/TNFRSF1A/ROCK1/RB1	6
GO:1905521	regulation of macrophage migration	6/896	41/18722	0.0126835388889186	0.0482619569669909	CCL3/C5AR1/CX3CR1/CSF1R/PTK2B/MAPK1	6
GO:0031279	regulation of cyclase activity	7/896	53/18722	0.0127034453158644	0.0482619569669909	GNAI2/P2RY13/CAP1/CCR2/CALM2/TIMP2/GNAI3	7
GO:0045806	negative regulation of endocytosis	7/896	53/18722	0.0127034453158644	0.0482619569669909	LILRB1/RIN3/MCTP1/CD300A/ANKRD13D/PICALM/SDCBP	7
GO:0071320	cellular response to cAMP	7/896	53/18722	0.0127034453158644	0.0482619569669909	SLC8A1/PTAFR/AQP9/ZFP36L1/AHR/RAP1A/RAP1B	7
GO:0043491	protein kinase B signaling	18/896	211/18722	0.0128803391578682	0.0488982802628265	IL1B/CCL3/KLF4/ARRB2/MTDH/GPX1/CX3CR1/TGFB1/HBEGF/TNF/SH2B3/ZFP36L1/HCLS1/SETX/OSBPL8/RRAS/PTEN/CIB1	18
GO:0050796	regulation of insulin secretion	15/896	165/18722	0.0129507155233451	0.0491295925871026	IL1B/HLA-DRB1/JAK2/UCP2/TNF/TCIRG1/ALOX5/SERP1/GLUL/MIDN/NADK/HIF1A/ACSL4/IRS2/PPP3CA	15
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	9/896	79/18722	0.0129871307122994	0.0492318271389718	NCF1/HCST/FGR/PTPN6/JAK2/PIK3AP1/TNF/FYN/HCLS1	9
GO:0009264	deoxyribonucleotide catabolic process	5/896	30/18722	0.0130626959598825	0.049410241227163	TYMP/SAMHD1/DPYD/UPP1/NUDT16	5
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	5/896	30/18722	0.0130626959598825	0.049410241227163	TGFB1/CALM2/PRKAG2/MAPK1/CAB39	5
GO:0070498	interleukin-1-mediated signaling pathway	5/896	30/18722	0.0130626959598825	0.049410241227163	IL1B/EGR1/IRAK3/IL1RN/MYD88	5
GO:0043270	positive regulation of ion transport	22/896	275/18722	0.0130871495533073	0.0494667622287438	CTSS/IL1B/TSPO/TMSB4X/VMP1/CCL3/FLNA/ARRB2/IFNGR2/CEBPB/CCR1/CCR2/KCNE3/LILRA5/LILRA2/PTAFR/CCL4/GLRX/CALM2/G6PD/CHP1/WNK1	22
GO:0042177	negative regulation of protein catabolic process	12/896	121/18722	0.0131865111106614	0.0498061323794843	CST3/TIMP1/FLNA/IRAK3/FYN/TIMP2/ROCK1/SDCBP/MYCBP2/MDM4/CTSA/WAC	12
GO:0097306	cellular response to alcohol	10/896	93/18722	0.0133918738455838	0.0500993133230632	CYBB/SOD2/KLF2/SPI1/KLF4/AHR/PTEN/ADCY7/GNB1/XRN1	10
GO:0051341	regulation of oxidoreductase activity	11/896	107/18722	0.0134189592448802	0.0500993133230632	IL1B/CYBA/LRRK2/GNAI2/TNF/GCH1/PTK2B/HIF1A/OXA1L/GNAI3/NFKB1	11
GO:0001660	fever generation	3/896	11/18722	0.0135049485250788	0.0500993133230632	IL1B/PTGS2/TNF	3
GO:0002327	immature B cell differentiation	3/896	11/18722	0.0135049485250788	0.0500993133230632	SPI1/ATM/IRF2BP2	3
GO:0002357	defense response to tumor cell	3/896	11/18722	0.0135049485250788	0.0500993133230632	LAPTM5/SPI1/KLF4	3
GO:0002645	positive regulation of tolerance induction	3/896	11/18722	0.0135049485250788	0.0500993133230632	LILRB2/IRAK3/TGFBR2	3
GO:0002732	positive regulation of dendritic cell cytokine production	3/896	11/18722	0.0135049485250788	0.0500993133230632	CLEC7A/SCIMP/DDX21	3
GO:0007042	lysosomal lumen acidification	3/896	11/18722	0.0135049485250788	0.0500993133230632	PPT1/GRN/ATP6AP2	3
GO:0019372	lipoxygenase pathway	3/896	11/18722	0.0135049485250788	0.0500993133230632	GPX1/ALOX5/ALOX5AP	3
GO:0031652	positive regulation of heat generation	3/896	11/18722	0.0135049485250788	0.0500993133230632	IL1B/PTGS2/TNF	3
GO:0033860	regulation of NAD(P)H oxidase activity	3/896	11/18722	0.0135049485250788	0.0500993133230632	CYBA/GNAI2/GNAI3	3
GO:0035457	cellular response to interferon-alpha	3/896	11/18722	0.0135049485250788	0.0500993133230632	IFIT2/IFIT3/IFNAR1	3
GO:0036490	regulation of translation in response to endoplasmic reticulum stress	3/896	11/18722	0.0135049485250788	0.0500993133230632	PPP1R15A/PPP1R15B/DDX3X	3
GO:0042167	heme catabolic process	3/896	11/18722	0.0135049485250788	0.0500993133230632	BLVRB/BLVRA/HMOX1	3
GO:0042789	mRNA transcription by RNA polymerase II	3/896	11/18722	0.0135049485250788	0.0500993133230632	C5AR1/FLNA/STAT3	3
GO:0045060	negative thymic T cell selection	3/896	11/18722	0.0135049485250788	0.0500993133230632	PTPRC/CD74/DOCK2	3
GO:0045628	regulation of T-helper 2 cell differentiation	3/896	11/18722	0.0135049485250788	0.0500993133230632	CD86/NLRP3/BCL6	3
GO:0046149	pigment catabolic process	3/896	11/18722	0.0135049485250788	0.0500993133230632	BLVRB/BLVRA/HMOX1	3
GO:0072110	glomerular mesangial cell proliferation	3/896	11/18722	0.0135049485250788	0.0500993133230632	EGR1/IL6R/CFLAR	3
GO:0097048	dendritic cell apoptotic process	3/896	11/18722	0.0135049485250788	0.0500993133230632	LYN/LILRB1/LGALS9	3
GO:1902065	response to L-glutamate	3/896	11/18722	0.0135049485250788	0.0500993133230632	FYN/TMBIM6/CREB1	3
GO:1903238	positive regulation of leukocyte tethering or rolling	3/896	11/18722	0.0135049485250788	0.0500993133230632	ITGA4/CCR2/PTAFR	3
GO:1903897	regulation of PERK-mediated unfolded protein response	3/896	11/18722	0.0135049485250788	0.0500993133230632	PPP1R15A/PPP1R15B/PTPN2	3
GO:1905668	positive regulation of protein localization to endosome	3/896	11/18722	0.0135049485250788	0.0500993133230632	MSN/SORL1/DTX3L	3
GO:2000668	regulation of dendritic cell apoptotic process	3/896	11/18722	0.0135049485250788	0.0500993133230632	LYN/LILRB1/LGALS9	3
GO:0043535	regulation of blood vessel endothelial cell migration	14/896	151/18722	0.0136648084075522	0.0502743783514024	TMSB4X/KLF4/PTGS2/MEF2C/TGFB1/TNF/RHOA/MAP3K3/HIF1A/PRCP/HMOX1/SP1/ADAM17/CIB1	14
GO:0055067	monovalent inorganic cation homeostasis	14/896	151/18722	0.0136648084075522	0.0502743783514024	LRRK2/SLC11A1/DMXL2/GNAI2/PPT1/GRN/SLC8A1/TCIRG1/HVCN1/PDK4/CHP1/ATP6V0D1/MAPK1/ATP6AP2	14
GO:0003159	morphogenesis of an endothelium	4/896	20/18722	0.0136681351641767	0.0502743783514024	RHOB/CXCR4/RHOA/ITGAX	4
GO:0007194	negative regulation of adenylate cyclase activity	4/896	20/18722	0.0136681351641767	0.0502743783514024	GNAI2/P2RY13/CCR2/GNAI3	4
GO:0010042	response to manganese ion	4/896	20/18722	0.0136681351641767	0.0502743783514024	TSPO/SOD2/LRRK2/PTGS2	4
GO:0034104	negative regulation of tissue remodeling	4/896	20/18722	0.0136681351641767	0.0502743783514024	CST3/TNFAIP3/CSK/INPP5D	4
GO:0039535	regulation of RIG-I signaling pathway	4/896	20/18722	0.0136681351641767	0.0502743783514024	USP15/BIRC3/SEC14L1/BIRC2	4
GO:0043011	myeloid dendritic cell differentiation	4/896	20/18722	0.0136681351641767	0.0502743783514024	SPI1/NOTCH2/TGFBR2/LTBR	4
GO:0043555	regulation of translation in response to stress	4/896	20/18722	0.0136681351641767	0.0502743783514024	PPP1R15A/RPS6KA3/PPP1R15B/DDX3X	4
GO:0060252	positive regulation of glial cell proliferation	4/896	20/18722	0.0136681351641767	0.0502743783514024	IL1B/TSPO/LYN/TNF	4
GO:0061154	endothelial tube morphogenesis	4/896	20/18722	0.0136681351641767	0.0502743783514024	RHOB/CXCR4/RHOA/ITGAX	4
GO:1902004	positive regulation of amyloid-beta formation	4/896	20/18722	0.0136681351641767	0.0502743783514024	TNF/IFNGR1/PICALM/SP1	4
GO:0051960	regulation of nervous system development	32/896	443/18722	0.0137560716068588	0.0505620695599101	IL1B/TYMP/TSPO/TNFRSF1B/B2M/LYN/ACTR2/CX3CR1/TLR2/TGFB1/NUMB/SORL1/CXCR4/PLXNC1/TNF/ITGAX/ARHGAP4/SKIL/NIN/SHTN1/PAK1/TWF2/PTEN/HIF1A/PLXNB2/DBNL/SPEN/DICER1/PPP3CA/DYNLT1/HOOK3/CTDSP1	32
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	7/896	54/18722	0.0140103877995697	0.051387890026205	PTPRC/PTPN6/LILRB1/HLA-F/NCKAP1L/BCL6/AHR	7
GO:0030834	regulation of actin filament depolymerization	7/896	54/18722	0.0140103877995697	0.051387890026205	PLEK/CAPG/CAPZA1/MTPN/CAPZA2/TWF2/FLII	7
GO:0051208	sequestering of calcium ion	12/896	122/18722	0.0140103880132972	0.051387890026205	CYBA/PTPRC/CORO1A/CCL3/LYN/PTPN6/SLC8A1/PTK2B/FKBP1A/CALM2/PRKACA/DIAPH1	12
GO:0048145	regulation of fibroblast proliferation	9/896	80/18722	0.014032220219629	0.0514316965202892	CD74/S100A6/IFI30/FTH1/CD300A/CDKN1A/FOSL2/MORC3/CREB1	9
GO:0048017	inositol lipid-mediated signaling	16/896	182/18722	0.0141343098908053	0.0517329667431939	NCF1/HCST/KLF4/FGR/PTPN6/JAK2/PIK3AP1/CSF1R/TNF/PTAFR/FYN/PLCB2/ZFP36L1/HCLS1/ADAP2/PTEN	16
GO:0060401	cytosolic calcium ion transport	16/896	182/18722	0.0141343098908053	0.0517329667431939	CYBA/PTPRC/CORO1A/CCL3/LYN/PTPN6/SLC8A1/FYN/PTK2B/FKBP1A/CALM2/PRKACA/DIAPH1/MICU1/TMBIM6/PRNP	16
GO:0071695	anatomical structure maturation	19/896	229/18722	0.0142136828390885	0.0517725409292481	KLF2/LRRK2/CLEC7A/SNX10/NR4A2/CX3CR1/RHOA/LYL1/BTK/PTK2B/G6PD/CDKN1A/PRKACA/PTBP3/SCLT1/RB1/HIF1A/ATP6AP2/ZBTB7A	19
GO:0010939	regulation of necrotic cell death	6/896	42/18722	0.014214802623912	0.0517725409292481	TSPO/BIRC3/CFLAR/CYLD/ASAH1/BIRC2	6
GO:0032689	negative regulation of interferon-gamma production	6/896	42/18722	0.014214802623912	0.0517725409292481	LAPTM5/HLA-DRB1/LILRB1/LGALS9/TLR4/PRNP	6
GO:0033574	response to testosterone	6/896	42/18722	0.014214802623912	0.0517725409292481	TSPO/DUSP1/MSN/CFLAR/NCOA4/XRN1	6
GO:0051602	response to electrical stimulus	6/896	42/18722	0.014214802623912	0.0517725409292481	AIF1/CD14/SOD2/BTG2/NR4A1/PTEN	6
GO:0072595	maintenance of protein localization in organelle	6/896	42/18722	0.014214802623912	0.0517725409292481	TSPO/SP100/CHCHD10/SUN2/HNRNPU/MORC3	6
GO:2001222	regulation of neuron migration	6/896	42/18722	0.014214802623912	0.0517725409292481	FLNA/PHACTR1/SHTN1/STAT3/PLXNB2/NIPBL	6
GO:0032409	regulation of transporter activity	24/896	310/18722	0.0143031510005459	0.0520254926533405	CTSS/TMSB4X/VMP1/FXYD5/ACTB/MEF2C/IFNGR2/CCR2/KCNE3/PTAFR/PTK2B/GLRX/FKBP1A/AHNAK/CALM2/CHP1/SGK1/PRKACA/PTEN/RXRA/CAB39/PRNP/WNK1/KMT2A	24
GO:0006879	cellular iron ion homeostasis	8/896	67/18722	0.0143242656180703	0.0520254926533405	SLC11A1/FTL/FTH1/ATP6V0D1/ATP6V1A/HIF1A/NCOA4/HMOX1	8
GO:0010517	regulation of phospholipase activity	8/896	67/18722	0.0143242656180703	0.0520254926533405	RGS2/C5AR1/PPT1/CD86/PTAFR/PLCB2/GNAQ/GNA13	8
GO:1903317	regulation of protein maturation	8/896	67/18722	0.0143242656180703	0.0520254926533405	CARD16/LRRK2/CTSZ/PRKACA/CAST/CARD8/MYH9/PRNP	8
GO:0007517	muscle organ development	25/896	327/18722	0.0145566011401319	0.0528324372155103	FOS/VAMP5/EGR1/BTG2/NR4A1/MEF2C/GPCPD1/GPX1/TGFB1/HBEGF/RHOA/SERP1/FKBP1A/MEF2A/FOXN2/MTPN/DDX5/CFLAR/RB1/ATF3/EEF2/PPP3CA/PLEC/EP300/CREB1	25
GO:0006690	icosanoid metabolic process	12/896	123/18722	0.0148728737205847	0.0539426891358165	IL1B/CD74/PTGS2/CYP1B1/LTA4H/GPX1/TLR2/SYK/ALOX5/TBXAS1/ALOX5AP/TNFRSF1A	12
GO:0002230	positive regulation of defense response to virus by host	5/896	31/18722	0.014976367503231	0.0540917273502116	PYCARD/STAT1/LILRB1/PARP9/DTX3L	5
GO:0016577	histone demethylation	5/896	31/18722	0.014976367503231	0.0540917273502116	KDM1B/JMJD1C/KDM6B/KDM7A/KDM5A	5
GO:0034656	nucleobase-containing small molecule catabolic process	5/896	31/18722	0.014976367503231	0.0540917273502116	APOBEC3A/DPYD/CDA/UPP1/MGAT1	5
GO:0046386	deoxyribose phosphate catabolic process	5/896	31/18722	0.014976367503231	0.0540917273502116	TYMP/SAMHD1/DPYD/UPP1/NUDT16	5
GO:0055022	negative regulation of cardiac muscle tissue growth	5/896	31/18722	0.014976367503231	0.0540917273502116	RGS2/G6PD/PAK1/PTEN/TGFBR2	5
GO:0061117	negative regulation of heart growth	5/896	31/18722	0.014976367503231	0.0540917273502116	RGS2/G6PD/PAK1/PTEN/TGFBR2	5
GO:0046879	hormone secretion	23/896	295/18722	0.0150553659267848	0.0543393186573266	IL1B/LYN/HLA-DRB1/RETN/JAK2/IL1RN/UCP2/TNF/TCIRG1/ALOX5/BTK/SERP1/GLUL/MIDN/CYB5R4/NADK/RAB8B/HIF1A/RAB11FIP1/ACSL4/IRS2/PPP3CA/CREB1	23
GO:0048144	fibroblast proliferation	9/896	81/18722	0.0151381795350717	0.05460032715805	CD74/S100A6/IFI30/FTH1/CD300A/CDKN1A/FOSL2/MORC3/CREB1	9
GO:0032414	positive regulation of ion transmembrane transporter activity	11/896	109/18722	0.0152593468663522	0.0549992120941773	CTSS/TMSB4X/VMP1/IFNGR2/CCR2/KCNE3/PTAFR/GLRX/CALM2/CHP1/WNK1	11
GO:0007044	cell-substrate junction assembly	10/896	95/18722	0.0153901662198425	0.05542942215044	IQGAP1/RHOA/PTK2B/TLN1/ROCK1/PTEN/LIMS1/CORO1C/DUSP22/PLEC	10
GO:0003179	heart valve morphogenesis	7/896	55/18722	0.0154106795673017	0.05542942215044	MEF2C/TGFB1/NOTCH2/ROCK1/RB1/TGFBR2/MDM4	7
GO:0043331	response to dsRNA	7/896	55/18722	0.0154106795673017	0.05542942215044	NFKBIA/IRAK3/RALB/MAPK1/IFIH1/DDX21/NFKB1	7
GO:0030900	forebrain development	28/896	379/18722	0.0154860249721359	0.0556619321907939	TYROBP/BCL2A1/B2M/LRRK2/FLNA/BTG2/NR4A2/NUMB/SLC8A1/CXCR4/ITGAM/RHOA/NRGN/PHACTR1/FYN/ZSWIM6/AGTPBP1/NIN/KDM6B/PTEN/HIF1A/SUN2/ARPC5/MBOAT7/XRN2/CELF1/HOOK3/CREB1	28
GO:0033173	calcineurin-NFAT signaling cascade	6/896	43/18722	0.0158701785679949	0.0569246887807872	CLEC7A/TNF/CHP1/PPP3CA/PRNP/CIB1	6
GO:0098927	vesicle-mediated transport between endosomal compartments	6/896	43/18722	0.0158701785679949	0.0569246887807872	CORO1A/MSN/FLNA/SORL1/MAPK1/HOOK3	6
GO:1904591	positive regulation of protein import	6/896	43/18722	0.0158701785679949	0.0569246887807872	FLNA/PTGS2/JAK2/TGFB1/HCLS1/MAPK1	6
GO:0045598	regulation of fat cell differentiation	13/896	139/18722	0.0159991419935646	0.0573146864409405	ZFP36/ZFP36L2/PTGS2/CEBPB/TGFB1/TNF/ALOX5/METRNL/ZFP36L1/STK4/ZNF385A/HNRNPU/CREB1	13
GO:0016052	carbohydrate catabolic process	14/896	154/18722	0.0160009468779553	0.0573146864409405	AOAH/FBP1/PRKAG2/STAT3/PGD/HIF1A/PGK1/PYGL/ZBTB7A/ADPGK/EP300/RB1CC1/CTBS/NAGA	14
GO:0021537	telencephalon development	20/896	248/18722	0.0160865666906317	0.0575817160068655	BCL2A1/LRRK2/FLNA/BTG2/NUMB/SLC8A1/CXCR4/RHOA/NRGN/PHACTR1/ZSWIM6/AGTPBP1/NIN/KDM6B/PTEN/HIF1A/SUN2/MBOAT7/XRN2/CELF1	20
GO:1904659	glucose transmembrane transport	11/896	110/18722	0.0162476897821641	0.0579168895533384	IL1B/SLC2A3/PRKCB/TNF/OSBPL8/MEF2A/RAP1A/PRKAG2/RHOQ/IRS2/PEA15	11
GO:0019370	leukotriene biosynthetic process	4/896	21/18722	0.016258153960368	0.0579168895533384	LTA4H/SYK/ALOX5/ALOX5AP	4
GO:0033630	positive regulation of cell adhesion mediated by integrin	4/896	21/18722	0.016258153960368	0.0579168895533384	PTPN6/NCKAP1L/SYK/CIB1	4
GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	4/896	21/18722	0.016258153960368	0.0579168895533384	STAT6/IL6R/SPN/STAT3	4
GO:0072111	cell proliferation involved in kidney development	4/896	21/18722	0.016258153960368	0.0579168895533384	EGR1/STAT1/IL6R/CFLAR	4
GO:0090026	positive regulation of monocyte chemotaxis	4/896	21/18722	0.016258153960368	0.0579168895533384	AIF1/CX3CR1/CCR1/CCR2	4
GO:1903427	negative regulation of reactive oxygen species biosynthetic process	4/896	21/18722	0.016258153960368	0.0579168895533384	RHOA/FYN/STAT3/CFLAR	4
GO:0001892	embryonic placenta development	9/896	82/18722	0.0163069475523941	0.0579715886671234	JUNB/SOCS3/CEBPB/ZFP36L1/STK4/GRB2/HIF1A/MAPK1/SP3	9
GO:0046889	positive regulation of lipid biosynthetic process	9/896	82/18722	0.0163069475523941	0.0579715886671234	IL1B/CD74/PTGS2/TNF/LPGAT1/CAPN2/CHP1/ELOVL5/CREB1	9
GO:1905897	regulation of response to endoplasmic reticulum stress	9/896	82/18722	0.0163069475523941	0.0579715886671234	LRRK2/ALOX5/HSPA1A/PPP1R15A/PPP1R15B/PTPN2/TMBIM6/GRINA/HERPUD1	9
GO:0010769	regulation of cell morphogenesis involved in differentiation	10/896	96/18722	0.0164686552362926	0.0584665364395615	FLNA/GBP1/ACTR2/MYADM/PREX1/CDC42/LIMS1/DBNL/CORO1C/CIB1	10
GO:1904035	regulation of epithelial cell apoptotic process	10/896	96/18722	0.0164686552362926	0.0584665364395615	ZFP36/TNFAIP3/ARRB2/ITGA4/JAK2/TNF/ZFP36L1/CFLAR/CAST/HMOX1	10
GO:0055007	cardiac muscle cell differentiation	12/896	125/18722	0.0167179885403528	0.0593112267383186	RGS2/ARRB2/MEF2C/TGFB1/SLC8A1/AKAP13/MEF2A/G6PD/PAK1/KDM6B/HNRNPU/PLEC	12
GO:0051966	regulation of synaptic transmission, glutamatergic	8/896	69/18722	0.0169031891003955	0.05990213517392	LRRK2/PTGS2/MEF2C/CCR2/TNF/PTK2B/GLUL/DGKZ	8
GO:0043388	positive regulation of DNA binding	7/896	56/18722	0.0169075820871591	0.05990213517392	KLF4/PLAUR/JAK2/TGFB1/CALM2/RB1/EP300	7
GO:0008217	regulation of blood pressure	16/896	186/18722	0.0170591493819698	0.0603910627930924	CYBA/SOD2/NAMPT/PTGS2/AGTRAP/CTSZ/SCPEP1/RHOA/PTAFR/GCH1/SGK1/ATP6AP2/PRCP/LNPEP/HMOX1/WNK1	16
GO:0006026	aminoglycan catabolic process	5/896	32/18722	0.017068806442193	0.0603910627930924	CD44/TGFB1/GNS/IDS/CTBS	5
GO:0006417	regulation of translation	33/896	468/18722	0.0172442296418465	0.0606500801750035	ZFP36/RGS2/VIM/ZFP36L2/BTG2/PABPC1/TNF/RHOA/RPS9/EIF1/PTAFR/PTK2B/SERP1/ZFP36L1/EIF4EBP1/PPP1R15A/MTPN/RPS6KA3/STAT3/CNBP/EIF2S3/ROCK1/MAPK1/PLXNB2/ZNF385A/PPP1R15B/EIF3K/YBX1/EEF2/QKI/CELF1/DDX3X/XRN1	33
GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	11/896	111/18722	0.0172831717483932	0.0606500801750035	NCF1/HCST/KLF4/FGR/PTPN6/JAK2/PIK3AP1/TNF/FYN/HCLS1/PTEN	11
GO:0002424	T cell mediated immune response to tumor cell	3/896	12/18722	0.0173752392733619	0.0606500801750035	HLA-A/HLA-DRB1/AHR	3
GO:0002664	regulation of T cell tolerance induction	3/896	12/18722	0.0173752392733619	0.0606500801750035	HLA-B/LILRB2/TGFBR2	3
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	3/896	12/18722	0.0173752392733619	0.0606500801750035	HLA-E/TNF/BTK	3
GO:0002903	negative regulation of B cell apoptotic process	3/896	12/18722	0.0173752392733619	0.0606500801750035	CD74/BCL6/IRS2	3
GO:0006787	porphyrin-containing compound catabolic process	3/896	12/18722	0.0173752392733619	0.0606500801750035	BLVRB/BLVRA/HMOX1	3
GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process	3/896	12/18722	0.0173752392733619	0.0606500801750035	TYMP/DPYD/UPP1	3
GO:0031953	negative regulation of protein autophosphorylation	3/896	12/18722	0.0173752392733619	0.0606500801750035	PTPRC/CHP1/MVP	3
GO:0032621	interleukin-18 production	3/896	12/18722	0.0173752392733619	0.0606500801750035	TLR2/GBP5/CD84	3
GO:0032661	regulation of interleukin-18 production	3/896	12/18722	0.0173752392733619	0.0606500801750035	TLR2/GBP5/CD84	3
GO:0033015	tetrapyrrole catabolic process	3/896	12/18722	0.0173752392733619	0.0606500801750035	BLVRB/BLVRA/HMOX1	3
GO:0034333	adherens junction assembly	3/896	12/18722	0.0173752392733619	0.0606500801750035	ACTB/PAK2/HIPK1	3
GO:0043383	negative T cell selection	3/896	12/18722	0.0173752392733619	0.0606500801750035	PTPRC/CD74/DOCK2	3
GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	3/896	12/18722	0.0173752392733619	0.0606500801750035	RGS2/G6PD/PAK1	3
GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress	3/896	12/18722	0.0173752392733619	0.0606500801750035	JUN/HSPA1A/TMBIM6	3
GO:1901503	ether biosynthetic process	3/896	12/18722	0.0173752392733619	0.0606500801750035	ALOX5/LPCAT2/FAR1	3
GO:1905666	regulation of protein localization to endosome	3/896	12/18722	0.0173752392733619	0.0606500801750035	MSN/SORL1/DTX3L	3
GO:2000727	positive regulation of cardiac muscle cell differentiation	3/896	12/18722	0.0173752392733619	0.0606500801750035	ARRB2/MEF2C/TGFB1	3
GO:2001204	regulation of osteoclast development	3/896	12/18722	0.0173752392733619	0.0606500801750035	TYROBP/LILRB1/NOTCH2	3
GO:0050803	regulation of synapse structure or activity	18/896	218/18722	0.0174588626690581	0.0609011031131934	SRGN/LRRK2/TUBA1A/LILRB2/ACTR2/MEF2C/PPT1/IL10RA/TLR2/TNF/RHOA/FYN/CFL1/CDC42/PTEN/ADAM10/DBNL/PRNP	18
GO:0014909	smooth muscle cell migration	10/896	97/18722	0.0176021035581755	0.0613596116662674	AIF1/MEF2C/IQGAP1/SORL1/RHOA/TLR4/TRIB1/PAK1/ARPC5/GNA13	10
GO:0030521	androgen receptor signaling pathway	6/896	44/18722	0.0176541151514076	0.06137637226101	RHOA/PKN1/DDX5/ZBTB7A/ARID1A/EP300	6
GO:0045124	regulation of bone resorption	6/896	44/18722	0.0176541151514076	0.06137637226101	TNFAIP3/SYK/CSF1R/CSK/INPP5D/PDK4	6
GO:0048066	developmental pigmentation	6/896	44/18722	0.0176541151514076	0.06137637226101	ZEB2/MEF2C/RAB32/RAB27A/ATP6AP2/BLOC1S6	6
GO:0097178	ruffle assembly	6/896	44/18722	0.0176541151514076	0.06137637226101	AIF1/SNX10/RHOG/PFN1/DBNL/CORO1C	6
GO:1990778	protein localization to cell periphery	25/896	333/18722	0.01785189985881	0.0620225325087982	VAMP5/FLNA/ACTB/GBP1/MYADM/TGFB1/RILPL2/NUMB/PRAM1/CCDC88A/CSK/TNF/RHOG/RAB8B/RAP1A/PICALM/RHOQ/TNFRSF1A/ROCK1/TSPAN14/ADAM10/RAB10/PRNP/STX7/CIB1	25
GO:0048732	gland development	31/896	436/18722	0.0185006719908042	0.064233641538166	TSPO/CRIP1/MSN/TNFAIP3/MAFB/PSAP/CEBPB/GPX1/JAK2/UCP2/TGFB1/NOTCH2/CSF1R/SULF2/OAS2/TNF/STAT6/RAP1A/CDC42/CFLAR/PTEN/HIF1A/MAPK1/HMOX1/TGFBR2/IRS2/TAF10/USF2/RB1CC1/SP3/CREB1	31
GO:0009150	purine ribonucleotide metabolic process	27/896	368/18722	0.0186508481817025	0.0647118488279085	TMSB4X/LRRK2/GIMAP7/PPT1/TGFB1/SULT1A1/RHOA/KYNU/ACSL1/FBP1/NUDT16/PDK4/PRKAG2/RHOQ/ELOVL5/ATP6V1A/STAT3/ADCY7/HIF1A/PGK1/NUDT3/ACSL4/ZBTB7A/ADPGK/FAR1/GNAI3/EP300	27
GO:0006911	phagocytosis, engulfment	12/896	127/18722	0.0187304505566457	0.0649447155634095	AIF1/ITGB2/CD36/FCGR1A/RAC2/NCKAP1L/ITGAM/CD300A/RHOG/CDC42/BIN2/MYH9	12
GO:0070301	cellular response to hydrogen peroxide	10/896	98/18722	0.0187920396526493	0.0651148555852291	KLF2/LRRK2/KLF4/RHOB/TNFAIP3/CYP1B1/STAT6/SETX/KDM6B/SIRPA	10
GO:0010660	regulation of muscle cell apoptotic process	9/896	84/18722	0.0188405425749038	0.0651960491896704	SOD2/ARRB2/JAK2/PTK2B/CAPN2/STK4/CFLAR/PTEN/HMOX1	9
GO:0097061	dendritic spine organization	9/896	84/18722	0.0188405425749038	0.0651960491896704	LRRK2/ACTR2/FYN/CFL1/CDC42/PTEN/ADAM10/DBNL/PRNP	9
GO:0010310	regulation of hydrogen peroxide metabolic process	4/896	22/18722	0.0191357141014442	0.0658233128582087	SOD2/RAC2/FYN/STAT3	4
GO:0032069	regulation of nuclease activity	4/896	22/18722	0.0191357141014442	0.0658233128582087	OAS1/OAS2/HSPA1A/TMBIM6	4
GO:0032816	positive regulation of natural killer cell activation	4/896	22/18722	0.0191357141014442	0.0658233128582087	TYROBP/HLA-E/HLA-F/BLOC1S6	4
GO:0045061	thymic T cell selection	4/896	22/18722	0.0191357141014442	0.0658233128582087	PTPRC/CD74/DOCK2/PTPN2	4
GO:0046628	positive regulation of insulin receptor signaling pathway	4/896	22/18722	0.0191357141014442	0.0658233128582087	GNAI2/SORL1/OSBPL8/PAK1	4
GO:0051220	cytoplasmic sequestering of protein	4/896	22/18722	0.0191357141014442	0.0658233128582087	TMSB4X/NFKBIA/FLNA/YWHAB	4
GO:0061042	vascular wound healing	4/896	22/18722	0.0191357141014442	0.0658233128582087	TNFAIP3/CXCR4/TNF/ALOX5	4
GO:0071404	cellular response to low-density lipoprotein particle stimulus	4/896	22/18722	0.0191357141014442	0.0658233128582087	FCER1G/ITGB2/CD36/SYK	4
GO:2000773	negative regulation of cellular senescence	4/896	22/18722	0.0191357141014442	0.0658233128582087	NAMPT/BCL6/MAP3K3/YBX1	4
GO:0001975	response to amphetamine	5/896	33/18722	0.0193461630530366	0.0661099829427354	RGS2/NR4A1/NR4A2/RGS10/PPP3CA	5
GO:0006482	protein demethylation	5/896	33/18722	0.0193461630530366	0.0661099829427354	KDM1B/JMJD1C/KDM6B/KDM7A/KDM5A	5
GO:0008214	protein dealkylation	5/896	33/18722	0.0193461630530366	0.0661099829427354	KDM1B/JMJD1C/KDM6B/KDM7A/KDM5A	5
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	5/896	33/18722	0.0193461630530366	0.0661099829427354	IL1B/PRKCB/HHEX/ITGA5/HIF1A	5
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	5/896	33/18722	0.0193461630530366	0.0661099829427354	LYN/FGR/TGFB1/PTK2B/CDC42	5
GO:0046685	response to arsenic-containing substance	5/896	33/18722	0.0193461630530366	0.0661099829427354	CDKN1A/PTEN/ATF3/HMOX1/DDX3X	5
GO:0071353	cellular response to interleukin-4	5/896	33/18722	0.0193461630530366	0.0661099829427354	CORO1A/STAT6/CD300LF/PARP14/PTPN2	5
GO:1901099	negative regulation of signal transduction in absence of ligand	5/896	33/18722	0.0193461630530366	0.0661099829427354	IL1B/MCL1/TNF/FYN/HSPA1A	5
GO:1902992	negative regulation of amyloid precursor protein catabolic process	5/896	33/18722	0.0193461630530366	0.0661099829427354	SORL1/PICALM/RTN3/ROCK1/PRNP	5
GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	5/896	33/18722	0.0193461630530366	0.0661099829427354	IL1B/MCL1/TNF/FYN/HSPA1A	5
GO:0006110	regulation of glycolytic process	6/896	45/18722	0.0195708596741188	0.0666588350786457	FBP1/PRKAG2/STAT3/HIF1A/ZBTB7A/EP300	6
GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	6/896	45/18722	0.0195708596741188	0.0666588350786457	SOD2/MCL1/CYP1B1/GPX1/JAK2/HIF1A	6
GO:0030835	negative regulation of actin filament depolymerization	6/896	45/18722	0.0195708596741188	0.0666588350786457	CAPG/CAPZA1/MTPN/CAPZA2/TWF2/FLII	6
GO:0071364	cellular response to epidermal growth factor stimulus	6/896	45/18722	0.0195708596741188	0.0666588350786457	ZFP36/ZFP36L2/IQGAP1/ZFP36L1/CFLAR/DUSP22	6
GO:1904646	cellular response to amyloid-beta	6/896	45/18722	0.0195708596741188	0.0666588350786457	NAMPT/CD36/ITGA4/TLR4/FYN/PRNP	6
GO:0071230	cellular response to amino acid stimulus	8/896	71/18722	0.0198003756865317	0.0673582161372059	CYBB/CYBA/CEBPB/TNF/FYN/LAMTOR4/CAPN2/LAMTOR1	8
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	12/896	128/18722	0.0198020981491613	0.0673582161372059	ZEB2/TGFB1/C20orf27/HSPA1A/FKBP1A/SKIL/SDCBP/ZBTB7A/ADAM17/CREBBP/EP300/FAM89B	12
GO:0003300	cardiac muscle hypertrophy	10/896	99/18722	0.0200399730136683	0.0680783145944407	RGS2/TNFRSF1B/AKAP13/MEF2A/G6PD/PAK1/MTPN/TNFRSF1A/ROCK1/PPP3CA	10
GO:0060996	dendritic spine development	10/896	99/18722	0.0200399730136683	0.0680783145944407	LRRK2/ACTR2/MEF2C/CFL1/PAK2/CDC42/PTEN/ADAM10/ACSL4/DBNL	10
GO:0001954	positive regulation of cell-matrix adhesion	7/896	58/18722	0.020203797800783	0.0684740029446864	CD36/IQGAP1/PTK2B/RRAS/ROCK1/LIMS1/CIB1	7
GO:0002931	response to ischemia	7/896	58/18722	0.020203797800783	0.0684740029446864	EGR1/CX3CR1/CSF1R/BID/EIF4EBP1/EEF2/CIB1	7
GO:0010043	response to zinc ion	7/896	58/18722	0.020203797800783	0.0684740029446864	S100A8/TSPO/SOD2/CRIP1/HVCN1/PTEN/CREB1	7
GO:0010507	negative regulation of autophagy	9/896	85/18722	0.0202091125783683	0.0684740029446864	TSPO/NAMPT/MCL1/LRRK2/IL10RA/STAT3/HMOX1/CTSA/SMG1	9
GO:0008645	hexose transmembrane transport	11/896	114/18722	0.0206850840936515	0.0700004480278716	IL1B/SLC2A3/PRKCB/TNF/OSBPL8/MEF2A/RAP1A/PRKAG2/RHOQ/IRS2/PEA15	11
GO:0090287	regulation of cellular response to growth factor stimulus	23/896	304/18722	0.0206865388615341	0.0700004480278716	IL1B/ZEB2/PRKCB/TGFB1/NOTCH2/SORL1/SULF2/C20orf27/HHEX/UBE2D1/HSPA1A/FKBP1A/SKIL/ITGA5/CFLAR/SDCBP/UBE2D3/HIF1A/ZBTB7A/ADAM17/CREBBP/EP300/FAM89B	23
GO:0001890	placenta development	13/896	144/18722	0.0208493566946887	0.0705055293687098	JUNB/PTGS2/SOCS3/CEBPB/NOTCH2/ZFP36L1/CTSB/STK4/GRB2/HIF1A/MAPK1/SP3/BIRC2	13
GO:0045807	positive regulation of endocytosis	10/896	100/18722	0.0213473914439338	0.0720928198898224	CD14/B2M/LRRK2/CD36/ARRB2/PPT1/NCKAP1L/SYK/CDC42/PPP3CA	10
GO:0030032	lamellipodium assembly	8/896	72/18722	0.0213741834781977	0.0720928198898224	ACTR2/WAS/RAC2/CCDC88A/ACTR3/TWF2/CDC42/BRK1	8
GO:0030330	DNA damage response, signal transduction by p53 class mediator	8/896	72/18722	0.0213741834781977	0.0720928198898224	CD74/CD44/SP100/CDKN1A/DDX5/ZNF385A/ATM/MDM4	8
GO:1901880	negative regulation of protein depolymerization	8/896	72/18722	0.0213741834781977	0.0720928198898224	CAPG/CAPZA1/MTPN/CAPZA2/TWF2/FLII/TAOK1/CIB1	8
GO:0050679	positive regulation of epithelial cell proliferation	17/896	207/18722	0.0214615029966149	0.0721724407386349	CYBA/JAML/C5AR1/TNFAIP3/NR4A1/ITGA4/GRN/NOTCH2/GPBAR1/GLUL/CDC42/STAT3/CFLAR/HIF1A/HMOX1/SP1/ADAM17	17
GO:0035094	response to nicotine	6/896	46/18722	0.02162444304825	0.0721724407386349	B2M/TNF/MAPK1/HMOX1/NFKB1/CREB1	6
GO:0044818	mitotic G2/M transition checkpoint	6/896	46/18722	0.02162444304825	0.0721724407386349	TAOK3/CDKN1A/ATM/NABP1/FOXN3/TAOK1	6
GO:1900271	regulation of long-term synaptic potentiation	6/896	46/18722	0.02162444304825	0.0721724407386349	TYROBP/LILRB2/CX3CR1/NRGN/PRNP/CREB1	6
GO:0006140	regulation of nucleotide metabolic process	9/896	86/18722	0.0216479693649499	0.0721724407386349	TMSB4X/CDA/FBP1/PDK4/PRKAG2/STAT3/HIF1A/ZBTB7A/EP300	9
GO:0035023	regulation of Rho protein signal transduction	9/896	86/18722	0.0216479693649499	0.0721724407386349	ARHGDIB/LPAR6/GPR65/BCL6/AKAP13/ARHGEF3/MYO9B/CDC42SE1/ARHGDIA	9
GO:0001768	establishment of T cell polarity	3/896	13/18722	0.0217979204232599	0.0721724407386349	DOCK2/DOCK8/MYH9	3
GO:0008298	intracellular mRNA localization	3/896	13/18722	0.0217979204232599	0.0721724407386349	ZFP36/ZFP36L1/ZNF385A	3
GO:0014842	regulation of skeletal muscle satellite cell proliferation	3/896	13/18722	0.0217979204232599	0.0721724407386349	JAK2/STAT3/CFLAR	3
GO:0016246	RNA interference	3/896	13/18722	0.0217979204232599	0.0721724407386349	ADAR/DICER1/CELF1	3
GO:0031392	regulation of prostaglandin biosynthetic process	3/896	13/18722	0.0217979204232599	0.0721724407386349	IL1B/CD74/PTGS2	3
GO:0032494	response to peptidoglycan	3/896	13/18722	0.0217979204232599	0.0721724407386349	C5AR1/IRAK3/MYD88	3
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	3/896	13/18722	0.0217979204232599	0.0721724407386349	LYN/TNFAIP3/LILRA2	3
GO:0036462	TRAIL-activated apoptotic signaling pathway	3/896	13/18722	0.0217979204232599	0.0721724407386349	SPI1/PTEN/ATF3	3
GO:0042492	gamma-delta T cell differentiation	3/896	13/18722	0.0217979204232599	0.0721724407386349	PTPRC/NCKAP1L/SYK	3
GO:0044090	positive regulation of vacuole organization	3/896	13/18722	0.0217979204232599	0.0721724407386349	GRN/RALB/PIP4K2A	3
GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	3/896	13/18722	0.0217979204232599	0.0721724407386349	NCF1/HBEGF/ADAM17	3
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	3/896	13/18722	0.0217979204232599	0.0721724407386349	ZFP36/BTG2/PABPC1	3
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	3/896	13/18722	0.0217979204232599	0.0721724407386349	EGR1/BACH1/HIF1A	3
GO:0072393	microtubule anchoring at microtubule organizing center	3/896	13/18722	0.0217979204232599	0.0721724407386349	NIN/BICD2/HOOK3	3
GO:1900044	regulation of protein K63-linked ubiquitination	3/896	13/18722	0.0217979204232599	0.0721724407386349	DDX3X/TRIP12/BIRC2	3
GO:1900272	negative regulation of long-term synaptic potentiation	3/896	13/18722	0.0217979204232599	0.0721724407386349	TYROBP/CX3CR1/PRNP	3
GO:1903977	positive regulation of glial cell migration	3/896	13/18722	0.0217979204232599	0.0721724407386349	CCL3/CX3CR1/CCR2	3
GO:0007095	mitotic G2 DNA damage checkpoint signaling	5/896	34/18722	0.0218140889907968	0.0721724407386349	TAOK3/CDKN1A/ATM/FOXN3/TAOK1	5
GO:0010614	negative regulation of cardiac muscle hypertrophy	5/896	34/18722	0.0218140889907968	0.0721724407386349	RGS2/TNFRSF1B/G6PD/PAK1/TNFRSF1A	5
GO:0032770	positive regulation of monooxygenase activity	5/896	34/18722	0.0218140889907968	0.0721724407386349	IL1B/TNF/GCH1/PTK2B/HIF1A	5
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	5/896	34/18722	0.0218140889907968	0.0721724407386349	CD74/CD44/DDX5/ZNF385A/ATM	5
GO:0050931	pigment cell differentiation	5/896	34/18722	0.0218140889907968	0.0721724407386349	ZEB2/MEF2C/RAB32/RAB27A/BLOC1S6	5
GO:0070232	regulation of T cell apoptotic process	5/896	34/18722	0.0218140889907968	0.0721724407386349	TSC22D3/LGALS9/GIMAP8/DOCK8/HIF1A	5
GO:0070884	regulation of calcineurin-NFAT signaling cascade	5/896	34/18722	0.0218140889907968	0.0721724407386349	CLEC7A/TNF/CHP1/PRNP/CIB1	5
GO:0051961	negative regulation of nervous system development	13/896	145/18722	0.0219386405396505	0.0725383785420994	IL1B/TSPO/B2M/TLR2/SORL1/TNF/ARHGAP4/PTEN/DICER1/PPP3CA/DYNLT1/HOOK3/CTDSP1	13
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	7/896	59/18722	0.0220091378374393	0.0727252388135464	LYN/KLF4/FGR/SOCS3/TGFB1/PTK2B/CDC42	7
GO:0009914	hormone transport	23/896	306/18722	0.0221360573718007	0.0730981805655462	IL1B/LYN/HLA-DRB1/RETN/JAK2/IL1RN/UCP2/TNF/TCIRG1/ALOX5/BTK/SERP1/GLUL/MIDN/CYB5R4/NADK/RAB8B/HIF1A/RAB11FIP1/ACSL4/IRS2/PPP3CA/CREB1	23
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	4/896	23/18722	0.0223086918718644	0.0732051609891151	CYBA/CTSZ/RHOA/ATP6AP2	4
GO:0006929	substrate-dependent cell migration	4/896	23/18722	0.0223086918718644	0.0732051609891151	PTPRC/STK4/SHTN1/SDCBP	4
GO:0010888	negative regulation of lipid storage	4/896	23/18722	0.0223086918718644	0.0732051609891151	NFKBIA/TNF/OSBPL8/PTPN2	4
GO:0031280	negative regulation of cyclase activity	4/896	23/18722	0.0223086918718644	0.0732051609891151	GNAI2/P2RY13/CCR2/GNAI3	4
GO:0035994	response to muscle stretch	4/896	23/18722	0.0223086918718644	0.0732051609891151	FOS/NFKBIA/SLC8A1/NFKB1	4
GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	4/896	23/18722	0.0223086918718644	0.0732051609891151	STAT6/IL6R/SPN/STAT3	4
GO:0060396	growth hormone receptor signaling pathway	4/896	23/18722	0.0223086918718644	0.0732051609891151	LYN/JAK2/STAT6/STAT3	4
GO:0071636	positive regulation of transforming growth factor beta production	4/896	23/18722	0.0223086918718644	0.0732051609891151	PTGS2/LGALS9/ATP6AP2/CREB1	4
GO:2000810	regulation of bicellular tight junction assembly	4/896	23/18722	0.0223086918718644	0.0732051609891151	TNF/GPBAR1/PRKACA/ROCK1	4
GO:0032984	protein-containing complex disassembly	18/896	224/18722	0.022309205954191	0.0732051609891151	VMP1/PLEK/IRAK3/CAPG/TNF/SETX/CFL1/CAPZA1/MTPN/CAPZA2/TWF2/FLII/ARID1A/CALCOCO2/TAOK1/CHMP1B/LAMP2/CIB1	18
GO:0098869	cellular oxidant detoxification	10/896	101/18722	0.0227157583689809	0.0744922189641045	S100A9/SOD2/CD36/PTGS2/GPX1/MGST1/GCH1/GLRX/ALOX5AP/GSTK1	10
GO:0048813	dendrite morphogenesis	13/896	146/18722	0.0230697584152796	0.0756054275474916	LRRK2/ACTR2/PHACTR1/FYN/MEF2A/CFL1/PICALM/CDC42/PTEN/ADAM10/DBNL/PPP3CA/ABI1	13
GO:1900182	positive regulation of protein localization to nucleus	9/896	87/18722	0.0231588933162719	0.0757067279308171	FLNA/PTGS2/JAK2/TGFB1/PARP9/FYN/HCLS1/DTX3L/MAPK1	9
GO:1901879	regulation of protein depolymerization	9/896	87/18722	0.0231588933162719	0.0757067279308171	PLEK/CAPG/CAPZA1/MTPN/CAPZA2/TWF2/FLII/TAOK1/CIB1	9
GO:1903578	regulation of ATP metabolic process	9/896	87/18722	0.0231588933162719	0.0757067279308171	TSPO/TMSB4X/RHOA/FBP1/PRKAG2/STAT3/HIF1A/ZBTB7A/EP300	9
GO:2000177	regulation of neural precursor cell proliferation	9/896	87/18722	0.0231588933162719	0.0757067279308171	LRRK2/LYN/FLNA/BTG2/GNAI2/CX3CR1/CTSZ/RHOA/HIF1A	9
GO:0015749	monosaccharide transmembrane transport	11/896	116/18722	0.0232116532366741	0.0757839350181683	IL1B/SLC2A3/PRKCB/TNF/OSBPL8/MEF2A/RAP1A/PRKAG2/RHOQ/IRS2/PEA15	11
GO:1990748	cellular detoxification	11/896	116/18722	0.0232116532366741	0.0757839350181683	S100A9/SOD2/CD36/PTGS2/GPX1/MGST1/ALDH1A1/GCH1/GLRX/ALOX5AP/GSTK1	11
GO:0061001	regulation of dendritic spine morphogenesis	6/896	47/18722	0.0238186659181464	0.0777169896112167	LRRK2/ACTR2/CFL1/PTEN/ADAM10/DBNL	6
GO:0006109	regulation of carbohydrate metabolic process	15/896	178/18722	0.0241133861167408	0.0785800258102563	PLEK/TGFB1/PTAFR/PTK2B/FBP1/MIDN/PDK4/PRKAG2/STAT3/HIF1A/ZBTB7A/IRS2/PTPN2/EP300/NFKB1	15
GO:0048015	phosphatidylinositol-mediated signaling	15/896	178/18722	0.0241133861167408	0.0785800258102563	NCF1/HCST/KLF4/FGR/PTPN6/JAK2/PIK3AP1/CSF1R/TNF/PTAFR/FYN/PLCB2/ZFP36L1/HCLS1/PTEN	15
GO:0014897	striated muscle hypertrophy	10/896	102/18722	0.024146510190199	0.0786386972443488	RGS2/TNFRSF1B/AKAP13/MEF2A/G6PD/PAK1/MTPN/TNFRSF1A/ROCK1/PPP3CA	10
GO:0006691	leukotriene metabolic process	5/896	35/18722	0.0244777181451327	0.0794685468619444	LTA4H/TLR2/SYK/ALOX5/ALOX5AP	5
GO:0032814	regulation of natural killer cell activation	5/896	35/18722	0.0244777181451327	0.0794685468619444	TYROBP/FGR/HLA-E/HLA-F/BLOC1S6	5
GO:0039694	viral RNA genome replication	5/896	35/18722	0.0244777181451327	0.0794685468619444	APOBEC3A/CXCL8/ATG16L2/CDC42/PCBP2	5
GO:0097421	liver regeneration	5/896	35/18722	0.0244777181451327	0.0794685468619444	CEBPB/UCP2/SULF2/RAP1A/HMOX1	5
GO:0106056	regulation of calcineurin-mediated signaling	5/896	35/18722	0.0244777181451327	0.0794685468619444	CLEC7A/TNF/CHP1/PRNP/CIB1	5
GO:0007569	cell aging	12/896	132/18722	0.024549178718633	0.0796238194848479	NAMPT/B2M/SPI1/BCL6/MAP3K3/CDKN1A/PTEN/LIMS1/ATM/YBX1/NUP62/MORC3	12
GO:1903828	negative regulation of cellular protein localization	11/896	117/18722	0.024556163517342	0.0796238194848479	SPI1/LRRK2/CD36/GBP1/TGFB1/NUMB/CSK/SP100/CHP1/PICALM/RHOQ	11
GO:0030101	natural killer cell activation	9/896	88/18722	0.0247436215302026	0.0801816670271549	TYROBP/PTPRC/CORO1A/FGR/HLA-E/HLA-F/RAB27A/BLOC1S6/SP3	9
GO:0050807	regulation of synapse organization	17/896	211/18722	0.0252786783250082	0.0818645118109389	SRGN/LRRK2/TUBA1A/LILRB2/ACTR2/MEF2C/IL10RA/TLR2/TNF/RHOA/FYN/CFL1/CDC42/PTEN/ADAM10/DBNL/PRNP	17
GO:0010212	response to ionizing radiation	13/896	148/18722	0.0254609984206428	0.0823523960110469	CYBA/PTPRC/NAMPT/EGR1/IFI16/RHOB/GPX1/GRB2/CDKN1A/TANK/NIPBL/ATM/NABP1	13
GO:0043484	regulation of RNA splicing	13/896	148/18722	0.0254609984206428	0.0823523960110469	MBNL1/CELF2/HSPA1A/SETX/AHNAK/DDX5/PTBP3/ZBTB7A/HNRNPU/CLK1/QKI/TMBIM6/CELF1	13
GO:0002726	positive regulation of T cell cytokine production	4/896	24/18722	0.0257835513526683	0.0829315093291453	IL1B/HLA-A/B2M/NLRP3	4
GO:0030859	polarized epithelial cell differentiation	4/896	24/18722	0.0257835513526683	0.0829315093291453	MSN/RHOA/CDC42/RAB10	4
GO:0033032	regulation of myeloid cell apoptotic process	4/896	24/18722	0.0257835513526683	0.0829315093291453	MEF2C/IRF7/PTEN/ADAM17	4
GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	4/896	24/18722	0.0257835513526683	0.0829315093291453	KLF2/CEBPB/HIF1A/ATF3	4
GO:0039531	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	4/896	24/18722	0.0257835513526683	0.0829315093291453	USP15/BIRC3/SEC14L1/BIRC2	4
GO:0051000	positive regulation of nitric-oxide synthase activity	4/896	24/18722	0.0257835513526683	0.0829315093291453	TNF/GCH1/PTK2B/HIF1A	4
GO:0071378	cellular response to growth hormone stimulus	4/896	24/18722	0.0257835513526683	0.0829315093291453	LYN/JAK2/STAT6/STAT3	4
GO:2000310	regulation of NMDA receptor activity	4/896	24/18722	0.0257835513526683	0.0829315093291453	MEF2C/IFNGR2/CCR2/PTK2B	4
GO:2000679	positive regulation of transcription regulatory region DNA binding	4/896	24/18722	0.0257835513526683	0.0829315093291453	KLF4/TGFB1/RB1/EP300	4
GO:0006163	purine nucleotide metabolic process	28/896	396/18722	0.0258445545298817	0.0830763461742366	TMSB4X/SAMHD1/LRRK2/GIMAP7/PPT1/TGFB1/SULT1A1/RHOA/KYNU/ACSL1/FBP1/NUDT16/PDK4/PRKAG2/RHOQ/ELOVL5/ATP6V1A/STAT3/ADCY7/HIF1A/PGK1/NUDT3/ACSL4/ZBTB7A/ADPGK/FAR1/GNAI3/EP300	28
GO:0060997	dendritic spine morphogenesis	7/896	61/18722	0.0259484689380145	0.0833328502347032	LRRK2/ACTR2/CFL1/CDC42/PTEN/ADAM10/DBNL	7
GO:0034219	carbohydrate transmembrane transport	11/896	118/18722	0.0259563963430531	0.0833328502347032	IL1B/SLC2A3/PRKCB/TNF/OSBPL8/MEF2A/RAP1A/PRKAG2/RHOQ/IRS2/PEA15	11
GO:0045912	negative regulation of carbohydrate metabolic process	6/896	48/18722	0.0261570861716456	0.0837703233859168	PLEK/TGFB1/FBP1/MIDN/STAT3/EP300	6
GO:0090199	regulation of release of cytochrome c from mitochondria	6/896	48/18722	0.0261570861716456	0.0837703233859168	PYCARD/TNFSF10/ARRB2/PLAUR/GPX1/BID	6
GO:0097720	calcineurin-mediated signaling	6/896	48/18722	0.0261570861716456	0.0837703233859168	CLEC7A/TNF/CHP1/PPP3CA/PRNP/CIB1	6
GO:1903053	regulation of extracellular matrix organization	6/896	48/18722	0.0261570861716456	0.0837703233859168	CST3/TNFRSF1B/TGFB1/TNFRSF1A/CFLAR/RB1	6
GO:0009749	response to glucose	17/896	212/18722	0.0263082332467015	0.0842025360714426	CYBA/TXNIP/LGALS1/EGR1/HLA-DRB1/UCP2/SLC8A1/RHOA/PTK2B/GLUL/NADK/PRKACA/PTEN/HIF1A/TGFBR2/IRS2/PPP3CA	17
GO:0010721	negative regulation of cell development	15/896	180/18722	0.0263272248234282	0.0842114983435733	IL1B/TSPO/B2M/GBP1/LILRB1/SORL1/TNF/ARHGAP4/PTEN/CORO1C/DICER1/PPP3CA/DYNLT1/HOOK3/CTDSP1	15
GO:0014910	regulation of smooth muscle cell migration	9/896	89/18722	0.0264038441755762	0.0843560864458934	AIF1/MEF2C/IQGAP1/SORL1/RHOA/TLR4/TRIB1/PAK1/GNA13	9
GO:0090276	regulation of peptide hormone secretion	16/896	196/18722	0.0264048661284204	0.0843560864458934	IL1B/HLA-DRB1/JAK2/UCP2/TNF/TCIRG1/ALOX5/SERP1/GLUL/MIDN/NADK/RAB8B/HIF1A/ACSL4/IRS2/PPP3CA	16
GO:0022898	regulation of transmembrane transporter activity	21/896	278/18722	0.026573315860525	0.084552548331415	CTSS/TMSB4X/VMP1/FXYD5/ACTB/MEF2C/IFNGR2/CCR2/KCNE3/PTAFR/PTK2B/GLRX/FKBP1A/AHNAK/CALM2/CHP1/PRKACA/PTEN/CAB39/PRNP/WNK1	21
GO:0001767	establishment of lymphocyte polarity	3/896	14/18722	0.0267752445879332	0.084552548331415	DOCK2/DOCK8/MYH9	3
GO:0001771	immunological synapse formation	3/896	14/18722	0.0267752445879332	0.084552548331415	MSN/DOCK2/DOCK8	3
GO:0002091	negative regulation of receptor internalization	3/896	14/18722	0.0267752445879332	0.084552548331415	RIN3/ANKRD13D/SDCBP	3
GO:0002475	antigen processing and presentation via MHC class Ib	3/896	14/18722	0.0267752445879332	0.084552548331415	B2M/HLA-E/HLA-F	3
GO:0002517	T cell tolerance induction	3/896	14/18722	0.0267752445879332	0.084552548331415	HLA-B/LILRB2/TGFBR2	3
GO:0002756	MyD88-independent toll-like receptor signaling pathway	3/896	14/18722	0.0267752445879332	0.084552548331415	TLR4/CD300LF/IRF7	3
GO:0002829	negative regulation of type 2 immune response	3/896	14/18722	0.0267752445879332	0.084552548331415	CCR2/STAT6/BCL6	3
GO:0009159	deoxyribonucleoside monophosphate catabolic process	3/896	14/18722	0.0267752445879332	0.084552548331415	TYMP/DPYD/UPP1	3
GO:0030213	hyaluronan biosynthetic process	3/896	14/18722	0.0267752445879332	0.084552548331415	IL1B/TGFB1/NFKB1	3
GO:0031650	regulation of heat generation	3/896	14/18722	0.0267752445879332	0.084552548331415	IL1B/PTGS2/TNF	3
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	3/896	14/18722	0.0267752445879332	0.084552548331415	DDX5/ZNF385A/ATM	3
GO:0043922	negative regulation by host of viral transcription	3/896	14/18722	0.0267752445879332	0.084552548331415	CCL3/CCL4/JUN	3
GO:0046131	pyrimidine ribonucleoside metabolic process	3/896	14/18722	0.0267752445879332	0.084552548331415	APOBEC3A/CDA/UPP1	3
GO:0046133	pyrimidine ribonucleoside catabolic process	3/896	14/18722	0.0267752445879332	0.084552548331415	APOBEC3A/CDA/UPP1	3
GO:0071236	cellular response to antibiotic	3/896	14/18722	0.0267752445879332	0.084552548331415	CRIP1/ACTR2/MEF2C	3
GO:0086103	G protein-coupled receptor signaling pathway involved in heart process	3/896	14/18722	0.0267752445879332	0.084552548331415	RGS2/GNAI2/AKAP13	3
GO:1901722	regulation of cell proliferation involved in kidney development	3/896	14/18722	0.0267752445879332	0.084552548331415	EGR1/IL6R/CFLAR	3
GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	3/896	14/18722	0.0267752445879332	0.084552548331415	CD74/CD44/ZNF385A	3
GO:0060419	heart growth	10/896	104/18722	0.0272007634488737	0.0858441569766941	RGS2/DUSP6/MEF2C/AKAP13/G6PD/PAK1/PRKAR1A/PTEN/MAPK1/TGFBR2	10
GO:0010762	regulation of fibroblast migration	5/896	36/18722	0.0273416515938983	0.085975773845142	TGFB1/SLC8A1/ARHGAP4/PAK1/CORO1C	5
GO:0014741	negative regulation of muscle hypertrophy	5/896	36/18722	0.0273416515938983	0.085975773845142	RGS2/TNFRSF1B/G6PD/PAK1/TNFRSF1A	5
GO:0051385	response to mineralocorticoid	5/896	36/18722	0.0273416515938983	0.085975773845142	CYBB/CYBA/FOS/FOSB/CDKN1A	5
GO:0070670	response to interleukin-4	5/896	36/18722	0.0273416515938983	0.085975773845142	CORO1A/STAT6/CD300LF/PARP14/PTPN2	5
GO:1901658	glycosyl compound catabolic process	5/896	36/18722	0.0273416515938983	0.085975773845142	APOBEC3A/DPYD/CDA/UPP1/NAGA	5
GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	5/896	36/18722	0.0273416515938983	0.085975773845142	CD74/CD44/BID/SKIL/ZNF385A	5
GO:0008361	regulation of cell size	15/896	181/18722	0.027489195918856	0.0863874972652388	MSN/PLEK/TMEM123/RHOA/ARHGAP4/LAMTOR4/DPYSL2/SHTN1/PAK1/MTPN/TWF2/PTEN/DBNL/RB1CC1/CREB1	15
GO:0072521	purine-containing compound metabolic process	29/896	416/18722	0.0278552785707235	0.0874850868637276	TMSB4X/SAMHD1/LRRK2/DPYD/GIMAP7/PPT1/TGFB1/SULT1A1/RHOA/KYNU/ACSL1/FBP1/NUDT16/PDK4/PRKAG2/RHOQ/ELOVL5/ATP6V1A/STAT3/ADCY7/HIF1A/PGK1/NUDT3/ACSL4/ZBTB7A/ADPGK/FAR1/GNAI3/EP300	29
GO:0046173	polyol biosynthetic process	7/896	62/18722	0.0280877480902896	0.0881087924110955	PLEK/PTAFR/GCH1/PTK2B/SPTLC2/ASAH1/PPIP5K2	7
GO:0060135	maternal process involved in female pregnancy	7/896	62/18722	0.0280877480902896	0.0881087924110955	RGS2/JUNB/PTGS2/LGALS9/CTSB/ADCY7/MAPK1	7
GO:0030901	midbrain development	9/896	90/18722	0.0281412009591185	0.0882232587030592	ACTB/NR4A2/RHOA/MBP/CALM2/G6PD/CDC42/GNB4/KDM7A	9
GO:0051236	establishment of RNA localization	14/896	166/18722	0.0284975753406076	0.0892866803292169	ZFP36/NUP214/MX2/HHEX/ZFP36L1/BICD2/ATM/YBX1/TGFBR2/NUP50/QKI/MVP/NUP62/SMG1	14
GO:0014855	striated muscle cell proliferation	8/896	76/18722	0.0285555237110041	0.0894143761715426	MEF2C/JAK2/PRKAR1A/STAT3/CFLAR/PTEN/MAPK1/TGFBR2	8
GO:0014075	response to amine	6/896	49/18722	0.0286430078458986	0.0894191379390868	RGS2/NR4A1/NR4A2/RGS10/HNMT/PPP3CA	6
GO:0042304	regulation of fatty acid biosynthetic process	6/896	49/18722	0.0286430078458986	0.0894191379390868	IL1B/CD74/PTGS2/LPGAT1/PDK4/ELOVL5	6
GO:0043330	response to exogenous dsRNA	6/896	49/18722	0.0286430078458986	0.0894191379390868	NFKBIA/IRAK3/RALB/MAPK1/IFIH1/DDX21	6
GO:0045778	positive regulation of ossification	6/896	49/18722	0.0286430078458986	0.0894191379390868	ISG15/MEF2C/TGFB1/SLC8A1/ALOX5/NIPBL	6
GO:0070169	positive regulation of biomineral tissue development	6/896	49/18722	0.0286430078458986	0.0894191379390868	ISG15/MEF2C/CEBPB/TGFB1/SLC8A1/ALOX5	6
GO:0003012	muscle system process	31/896	452/18722	0.0286729502761913	0.089458916848513	AIF1/IL1B/CYBA/RGS2/TNFRSF1B/FLNA/KLF4/PTGS2/NR4A1/TPM3/RCSD1/SCO2/SLC8A1/KCNE3/SULF2/CXCR4/RHOA/PTAFR/AKAP13/CALM2/MEF2A/G6PD/PAK1/MTPN/PRKACA/TNFRSF1A/CFLAR/ROCK1/HMOX1/EEF2/PPP3CA	31
GO:0045732	positive regulation of protein catabolic process	18/896	231/18722	0.0291964240938976	0.0910375310026148	IL1B/LAPTM5/TNFRSF1B/LRRK2/MSN/TNFAIP3/OAZ1/SORL1/TNF/PTK2B/HSPA1A/FBXL5/AGTPBP1/TRIB1/GABARAP/PTEN/PIAS1/HERPUD1	18
GO:0030318	melanocyte differentiation	4/896	25/18722	0.0295653674622718	0.0915839643664535	ZEB2/MEF2C/RAB27A/BLOC1S6	4
GO:0031579	membrane raft organization	4/896	25/18722	0.0295653674622718	0.0915839643664535	PTPRC/PPT1/MYADM/DOCK2	4
GO:0033622	integrin activation	4/896	25/18722	0.0295653674622718	0.0915839643664535	PLEK/FERMT3/TLN1/RAP1B	4
GO:0035336	long-chain fatty-acyl-CoA metabolic process	4/896	25/18722	0.0295653674622718	0.0915839643664535	ACSL1/ELOVL5/ACSL4/FAR1	4
GO:0046949	fatty-acyl-CoA biosynthetic process	4/896	25/18722	0.0295653674622718	0.0915839643664535	PPT1/ACSL1/ELOVL5/ACSL4	4
GO:0048143	astrocyte activation	4/896	25/18722	0.0295653674622718	0.0915839643664535	C5AR1/GRN/TNF/IFNGR1	4
GO:0090330	regulation of platelet aggregation	4/896	25/18722	0.0295653674622718	0.0915839643664535	LYN/JAK2/SYK/SH2B3	4
GO:1900078	positive regulation of cellular response to insulin stimulus	4/896	25/18722	0.0295653674622718	0.0915839643664535	GNAI2/SORL1/OSBPL8/PAK1	4
GO:1903901	negative regulation of viral life cycle	4/896	25/18722	0.0295653674622718	0.0915839643664535	FCN1/IFITM3/BST2/IFITM2	4
GO:1904385	cellular response to angiotensin	4/896	25/18722	0.0295653674622718	0.0915839643664535	CYBA/AGTRAP/ROCK1/NFKB1	4
GO:1905564	positive regulation of vascular endothelial cell proliferation	4/896	25/18722	0.0295653674622718	0.0915839643664535	ITGA4/STAT3/SP1/ADAM17	4
GO:0060191	regulation of lipase activity	9/896	91/18722	0.0299572777134803	0.0927427389213161	RGS2/C5AR1/PPT1/CD86/RHOA/PTAFR/PLCB2/GNAQ/GNA13	9
GO:0003176	aortic valve development	5/896	37/18722	0.030409946450255	0.0939763110444304	TNFRSF1B/TGFB1/TNFRSF1A/ROCK1/RB1	5
GO:0043029	T cell homeostasis	5/896	37/18722	0.030409946450255	0.0939763110444304	CORO1A/TSC22D3/LGALS9/NCKAP1L/TCIRG1	5
GO:0043403	skeletal muscle tissue regeneration	5/896	37/18722	0.030409946450255	0.0939763110444304	GPX1/MTPN/CFLAR/TGFBR2/PPP3CA	5
GO:0001824	blastocyst development	10/896	106/18722	0.0305210044350626	0.0940401327409718	JUNB/KLF4/LPAR6/PTPN18/CAPN2/CMTM3/SKIL/SMIM14/WDR74/SP3	10
GO:0002793	positive regulation of peptide secretion	10/896	106/18722	0.0305210044350626	0.0940401327409718	S100A8/HLA-DRB1/JAK2/SERP1/GLUL/NADK/RAB8B/HIF1A/ACSL4/IRS2	10
GO:0006090	pyruvate metabolic process	10/896	106/18722	0.0305210044350626	0.0940401327409718	FBP1/PDK4/PRKAG2/STAT3/HIF1A/PGK1/ZBTB7A/ADPGK/ME2/EP300	10
GO:0006906	vesicle fusion	10/896	106/18722	0.0305210044350626	0.0940401327409718	CORO1A/STX11/SAMD9/STX10/RAB8B/CHP1/PIP4K2A/GNAI3/STX7/STX12	10
GO:0046620	regulation of organ growth	10/896	106/18722	0.0305210044350626	0.0940401327409718	RGS2/DUSP6/MEF2C/SERP1/STK4/G6PD/PAK1/PTEN/MAPK1/TGFBR2	10
GO:0046883	regulation of hormone secretion	19/896	249/18722	0.0308248555804383	0.0949201147861811	IL1B/HLA-DRB1/RETN/JAK2/UCP2/TNF/TCIRG1/ALOX5/SERP1/GLUL/MIDN/NADK/RAB8B/HIF1A/RAB11FIP1/ACSL4/IRS2/PPP3CA/CREB1	19
GO:0034329	cell junction assembly	29/896	420/18722	0.0310413739288299	0.0955302874578959	IL1B/VMP1/ACTB/MTDH/MEF2C/PECAM1/IQGAP1/TLR2/TNF/GPBAR1/RHOA/PTK2B/CAPZA1/RAP1A/TLN1/PAK2/CDC42/PRKACA/ROCK1/SDCBP/PTEN/LIMS1/RAP1B/PLXNB2/DBNL/CORO1C/DUSP22/HIPK1/PLEC	29
GO:0050873	brown fat cell differentiation	6/896	50/18722	0.0312794714218065	0.0959790742565284	RGS2/PTGS2/PLAC8/CEBPB/METRNL/HNRNPU	6
GO:0060425	lung morphogenesis	6/896	50/18722	0.0312794714218065	0.0959790742565284	CTSH/CTSZ/TNF/CDC42/MAPK1/TGFBR2	6
GO:0110151	positive regulation of biomineralization	6/896	50/18722	0.0312794714218065	0.0959790742565284	ISG15/MEF2C/CEBPB/TGFB1/SLC8A1/ALOX5	6
GO:1901570	fatty acid derivative biosynthetic process	6/896	50/18722	0.0312794714218065	0.0959790742565284	PPT1/ALOX5/ACSL1/ELOVL5/ACSL4/FAR1	6
GO:2000677	regulation of transcription regulatory region DNA binding	6/896	50/18722	0.0312794714218065	0.0959790742565284	TMSB4X/KLF4/TGFB1/RB1/ZBTB7A/EP300	6
GO:0062012	regulation of small molecule metabolic process	24/896	334/18722	0.0314905764789424	0.0965698633649641	IL1B/TMSB4X/CD74/PLEK/EGR1/PTGS2/SLC7A7/CDA/TNF/LPGAT1/PTAFR/PTK2B/FBP1/MIDN/PDK4/PRKAG2/ELOVL5/STAT3/HIF1A/ZBTB7A/IRS2/PTPN2/EP300/NFKB1	24
GO:0030879	mammary gland development	12/896	137/18722	0.0315946266119752	0.0967748250935707	CEBPB/GPX1/JAK2/CSF1R/OAS2/STAT6/HIF1A/MAPK1/TGFBR2/IRS2/USF2/CREB1	12
GO:0050714	positive regulation of protein secretion	12/896	137/18722	0.0315946266119752	0.0967748250935707	HLA-DRB1/JAK2/TLR2/TGFB1/TLR4/CD33/SERP1/GLUL/NADK/HIF1A/ACSL4/IRS2	12
GO:0051928	positive regulation of calcium ion transport	11/896	122/18722	0.0321372062681528	0.0975298717153612	TSPO/VMP1/CCL3/ARRB2/CCR1/KCNE3/LILRA5/LILRA2/CCL4/CALM2/G6PD	11
GO:0032412	regulation of ion transmembrane transporter activity	20/896	267/18722	0.0322695994655161	0.0975298717153612	CTSS/TMSB4X/VMP1/FXYD5/MEF2C/IFNGR2/CCR2/KCNE3/PTAFR/PTK2B/GLRX/FKBP1A/AHNAK/CALM2/CHP1/PRKACA/PTEN/CAB39/PRNP/WNK1	20
GO:0050804	modulation of chemical synaptic transmission	30/896	439/18722	0.0322758007246965	0.0975298717153612	TYROBP/IL1B/SRGN/LRRK2/GNAI2/PTGS2/LILRB2/ARRB2/MEF2C/RETN/JAK2/CX3CR1/PRKCB/CCR2/TNF/NRGN/MCTP1/FYN/PTK2B/GLUL/RAP1A/PRKACA/STAT3/PTEN/MAPK1/RAP1B/DGKZ/PPP3CA/PRNP/CREB1	30
GO:0032526	response to retinoic acid	10/896	107/18722	0.0322841018773494	0.0975298717153612	DUSP1/LYN/KLF4/CTSH/PTK2B/SETX/TWF2/RXRA/ATM/CREB1	10
GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	10/896	107/18722	0.0322841018773494	0.0975298717153612	LAPTM5/LRRK2/PTK2B/HSPA1A/AGTPBP1/TRIB1/GABARAP/PTEN/PIAS1/HERPUD1	10
GO:0002679	respiratory burst involved in defense response	3/896	15/18722	0.0323049396377833	0.0975298717153612	NCF1/HCK/GRN	3
GO:0006878	cellular copper ion homeostasis	3/896	15/18722	0.0323049396377833	0.0975298717153612	SCO2/SLC31A2/PRNP	3
GO:0010763	positive regulation of fibroblast migration	3/896	15/18722	0.0323049396377833	0.0975298717153612	TGFB1/SLC8A1/PAK1	3
GO:0014841	skeletal muscle satellite cell proliferation	3/896	15/18722	0.0323049396377833	0.0975298717153612	JAK2/STAT3/CFLAR	3
GO:0014857	regulation of skeletal muscle cell proliferation	3/896	15/18722	0.0323049396377833	0.0975298717153612	JAK2/STAT3/CFLAR	3
GO:0023035	CD40 signaling pathway	3/896	15/18722	0.0323049396377833	0.0975298717153612	TNFAIP3/CD86/ITGA5	3
GO:0031958	corticosteroid receptor signaling pathway	3/896	15/18722	0.0323049396377833	0.0975298717153612	JAK2/ARID1A/NR3C1	3
GO:0032488	Cdc42 protein signal transduction	3/896	15/18722	0.0323049396377833	0.0975298717153612	WAS/SHTN1/CDC42	3
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	3/896	15/18722	0.0323049396377833	0.0975298717153612	IL1B/SYK/LILRA2	3
GO:0045064	T-helper 2 cell differentiation	3/896	15/18722	0.0323049396377833	0.0975298717153612	CD86/NLRP3/BCL6	3
GO:0045346	regulation of MHC class II biosynthetic process	3/896	15/18722	0.0323049396377833	0.0975298717153612	SPI1/JAK2/TLR4	3
GO:0046007	negative regulation of activated T cell proliferation	3/896	15/18722	0.0323049396377833	0.0975298717153612	LGALS9/PRKAR1A/PRNP	3
GO:0060099	regulation of phagocytosis, engulfment	3/896	15/18722	0.0323049396377833	0.0975298717153612	CD36/NCKAP1L/CD300A	3
GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening	3/896	15/18722	0.0323049396377833	0.0975298717153612	ZFP36/BTG2/PABPC1	3
GO:0098760	response to interleukin-7	3/896	15/18722	0.0323049396377833	0.0975298717153612	LSP1/BTK/YBX1	3
GO:0098761	cellular response to interleukin-7	3/896	15/18722	0.0323049396377833	0.0975298717153612	LSP1/BTK/YBX1	3
GO:0140374	antiviral innate immune response	3/896	15/18722	0.0323049396377833	0.0975298717153612	MX1/OAS1/CARD8	3
GO:2000345	regulation of hepatocyte proliferation	3/896	15/18722	0.0323049396377833	0.0975298717153612	TNFAIP3/SULF2/CFLAR	3
GO:2001279	regulation of unsaturated fatty acid biosynthetic process	3/896	15/18722	0.0323049396377833	0.0975298717153612	IL1B/CD74/PTGS2	3
GO:0006403	RNA localization	16/896	201/18722	0.032309934429065	0.0975298717153612	ZFP36/NUP214/MX2/HHEX/ZFP36L1/ZNF385A/BICD2/ATM/YBX1/TGFBR2/HNRNPU/NUP50/QKI/MVP/NUP62/SMG1	16
GO:0002040	sprouting angiogenesis	15/896	185/18722	0.0325191437196952	0.0980475747745707	KLF2/KLF4/PTGS2/RNF213/NR4A1/ALOX5/RHOA/MAP3K3/PTK2B/GLUL/JAK1/ITGA5/CDC42/HMOX1/CIB1	15
GO:0051896	regulation of protein kinase B signaling	15/896	185/18722	0.0325191437196952	0.0980475747745707	CCL3/KLF4/ARRB2/MTDH/GPX1/CX3CR1/TGFB1/HBEGF/TNF/SH2B3/HCLS1/OSBPL8/RRAS/PTEN/CIB1	15
GO:0008306	associative learning	8/896	78/18722	0.0327062529275645	0.0983611286291917	FOS/BTG2/ACTR2/PPT1/NRGN/HIF1A/PIAS1/CREB1	8
GO:0032024	positive regulation of insulin secretion	8/896	78/18722	0.0327062529275645	0.0983611286291917	HLA-DRB1/JAK2/SERP1/GLUL/NADK/HIF1A/ACSL4/IRS2	8
GO:0043297	apical junction assembly	8/896	78/18722	0.0327062529275645	0.0983611286291917	MTDH/PECAM1/TNF/GPBAR1/RHOA/PAK2/PRKACA/ROCK1	8
GO:0046579	positive regulation of Ras protein signal transduction	7/896	64/18722	0.0327176990056723	0.0983611286291917	NOTCH2/LPAR6/GPR65/AKAP13/ARHGEF3/SHOC2/DYNLT1	7
GO:0048857	neural nucleus development	7/896	64/18722	0.0327176990056723	0.0983611286291917	ACTB/RHOA/MBP/CALM2/G6PD/CDC42/GNB4	7
GO:0099177	regulation of trans-synaptic signaling	30/896	440/18722	0.0331211248331733	0.0995164472890437	TYROBP/IL1B/SRGN/LRRK2/GNAI2/PTGS2/LILRB2/ARRB2/MEF2C/RETN/JAK2/CX3CR1/PRKCB/CCR2/TNF/NRGN/MCTP1/FYN/PTK2B/GLUL/RAP1A/PRKACA/STAT3/PTEN/MAPK1/RAP1B/DGKZ/PPP3CA/PRNP/CREB1	30
GO:0050708	regulation of protein secretion	20/896	268/18722	0.0333722421777586	0.10021306672432	IL1B/HLA-DRB1/JAK2/UCP2/TLR2/TGFB1/TNF/TCIRG1/ALOX5/TLR4/CD33/SERP1/GLUL/MIDN/NADK/HIF1A/RAB11FIP1/ACSL4/IRS2/PPP3CA	20
GO:0006027	glycosaminoglycan catabolic process	4/896	26/18722	0.0336578589552853	0.100574885028824	CD44/TGFB1/GNS/IDS	4
GO:0009164	nucleoside catabolic process	4/896	26/18722	0.0336578589552853	0.100574885028824	APOBEC3A/DPYD/CDA/UPP1	4
GO:0032682	negative regulation of chemokine production	4/896	26/18722	0.0336578589552853	0.100574885028824	KLF4/LGALS9/OAS1/SIRPA	4
GO:0033598	mammary gland epithelial cell proliferation	4/896	26/18722	0.0336578589552853	0.100574885028824	CEBPB/GPX1/STAT6/MAPK1	4
GO:0046697	decidualization	4/896	26/18722	0.0336578589552853	0.100574885028824	JUNB/PTGS2/CTSB/MAPK1	4
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	4/896	26/18722	0.0336578589552853	0.100574885028824	PTPRC/PRKCB/NFAM1/CMTM3	4
GO:0051350	negative regulation of lyase activity	4/896	26/18722	0.0336578589552853	0.100574885028824	GNAI2/P2RY13/CCR2/GNAI3	4
GO:0060544	regulation of necroptotic process	4/896	26/18722	0.0336578589552853	0.100574885028824	BIRC3/CFLAR/CYLD/BIRC2	4
GO:0001825	blastocyst formation	5/896	38/18722	0.0336861083868895	0.100574885028824	JUNB/PTPN18/SKIL/WDR74/SP3	5
GO:0035337	fatty-acyl-CoA metabolic process	5/896	38/18722	0.0336861083868895	0.100574885028824	PPT1/ACSL1/ELOVL5/ACSL4/FAR1	5
GO:0106027	neuron projection organization	9/896	93/18722	0.0338316455363301	0.100951456359411	LRRK2/ACTR2/FYN/CFL1/CDC42/PTEN/ADAM10/DBNL/PRNP	9
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	6/896	51/18722	0.0340692454927145	0.101485765067358	PYCARD/TNFAIP3/STAT1/RHOA/CARD8/TANK	6
GO:0046850	regulation of bone remodeling	6/896	51/18722	0.0340692454927145	0.101485765067358	TNFAIP3/SYK/CSF1R/CSK/INPP5D/PDK4	6
GO:0051339	regulation of lyase activity	6/896	51/18722	0.0340692454927145	0.101485765067358	GNAI2/P2RY13/CAP1/CCR2/TIMP2/GNAI3	6
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	8/896	79/18722	0.0349281258532282	0.103865741888302	FLNA/ACTR2/MYADM/PREX1/CDC42/LIMS1/DBNL/CIB1	8
GO:0050772	positive regulation of axonogenesis	8/896	79/18722	0.0349281258532282	0.103865741888302	PLXNC1/SKIL/NIN/SHTN1/PAK1/TWF2/PLXNB2/DBNL	8
GO:0060420	regulation of heart growth	8/896	79/18722	0.0349281258532282	0.103865741888302	RGS2/DUSP6/MEF2C/G6PD/PAK1/PTEN/MAPK1/TGFBR2	8
GO:0030072	peptide hormone secretion	18/896	236/18722	0.0350114836509026	0.104054129410483	IL1B/HLA-DRB1/JAK2/IL1RN/UCP2/TNF/TCIRG1/ALOX5/SERP1/GLUL/MIDN/CYB5R4/NADK/RAB8B/HIF1A/ACSL4/IRS2/PPP3CA	18
GO:0090307	mitotic spindle assembly	7/896	65/18722	0.0352127876795332	0.104592637761994	FLNA/RHOA/HSPA1A/STAG2/HNRNPU/CHMP1B/ZNF207	7
GO:1903364	positive regulation of cellular protein catabolic process	13/896	155/18722	0.0352733909667557	0.104712846129051	LAPTM5/LRRK2/MSN/TNFAIP3/PTK2B/HSPA1A/FBXL5/AGTPBP1/TRIB1/GABARAP/PTEN/PIAS1/HERPUD1	13
GO:0046890	regulation of lipid biosynthetic process	14/896	171/18722	0.035409246642002	0.10499628950117	IL1B/TSPO/CD74/EGR1/PTGS2/TNF/LPGAT1/CAPN2/PDK4/CHP1/ELOVL5/ASAH1/NFKB1/CREB1	14
GO:0048469	cell maturation	14/896	171/18722	0.035409246642002	0.10499628950117	KLF2/LRRK2/CLEC7A/NR4A2/BTK/PTK2B/G6PD/CDKN1A/PRKACA/PTBP3/SCLT1/RB1/HIF1A/ZBTB7A	14
GO:0097237	cellular response to toxic substance	11/896	124/18722	0.0355906456078417	0.105474044334122	S100A9/SOD2/CD36/PTGS2/GPX1/MGST1/ALDH1A1/GCH1/GLRX/ALOX5AP/GSTK1	11
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	9/896	94/18722	0.035892810048356	0.10630894365689	ACTB/TNFAIP3/CCNL1/HHEX/CCNI/CDKN1A/CCNY/PTEN/ADAM17	9
GO:0071383	cellular response to steroid hormone stimulus	16/896	204/18722	0.0362887148134581	0.107420378909958	ZFP36/ZFP36L2/JAK2/RHOA/ZFP36L1/PKN1/PAK1/DDX5/CFLAR/RXRA/NCOA4/ZBTB7A/ARID1A/HNRNPU/NR3C1/EP300	16
GO:0030177	positive regulation of Wnt signaling pathway	12/896	140/18722	0.0364604213005779	0.107805941548781	ZEB2/LRRK2/TNFAIP3/TLR2/TGFB1/SULF2/HHEX/ATP6AP2/MBD2/DDX3X/WNK1/NFKB1	12
GO:0050768	negative regulation of neurogenesis	12/896	140/18722	0.0364604213005779	0.107805941548781	IL1B/TSPO/B2M/SORL1/TNF/ARHGAP4/PTEN/DICER1/PPP3CA/DYNLT1/HOOK3/CTDSP1	12
GO:0030308	negative regulation of cell growth	15/896	188/18722	0.0367101964638197	0.108482802163822	RGS2/BST2/PPT1/TGFB1/CDA/BCL6/ARHGAP4/FBP1/HSPA1A/G6PD/BTG1/PAK1/CDKN1A/RB1/DDX3X	15
GO:0035051	cardiocyte differentiation	13/896	156/18722	0.036869117448756	0.108890562095957	RGS2/ARRB2/MEF2C/TGFB1/SLC8A1/AKAP13/MEF2A/G6PD/PAK1/KDM6B/MAPK1/HNRNPU/PLEC	13
GO:0007219	Notch signaling pathway	14/896	172/18722	0.0369248460809725	0.108931437587713	NFKBIA/CFD/NOTCH2/LFNG/BCL6/DTX3L/STAT3/TSPAN14/ADAM10/BMP2K/ZBTB7A/SPEN/TGFBR2/ADAM17	14
GO:0042770	signal transduction in response to DNA damage	14/896	172/18722	0.0369248460809725	0.108931437587713	CD74/CD44/BID/SP100/TAOK3/GRB2/CDKN1A/DDX5/ZNF385A/ATM/MDM4/FOXN3/TAOK1/WAC	14
GO:0031103	axon regeneration	6/896	52/18722	0.0370148197854394	0.109073131843666	TSPO/FLNA/KLF4/JAK2/GRN/PTEN	6
GO:2000378	negative regulation of reactive oxygen species metabolic process	6/896	52/18722	0.0370148197854394	0.109073131843666	RHOA/FYN/G6PD/STAT3/CFLAR/HIF1A	6
GO:0016572	histone phosphorylation	5/896	39/18722	0.037173087612374	0.109415522734554	IL1B/JAK2/PRKCB/PKN1/ATM	5
GO:0046326	positive regulation of glucose import	5/896	39/18722	0.037173087612374	0.109415522734554	OSBPL8/MEF2A/RAP1A/RHOQ/IRS2	5
GO:0120193	tight junction organization	8/896	80/18722	0.0372498931458504	0.109579578196588	MTDH/PECAM1/TNF/GPBAR1/PAK2/PRKACA/ROCK1/PLEC	8
GO:0051893	regulation of focal adhesion assembly	7/896	66/18722	0.0378306334930419	0.110776048480721	IQGAP1/RHOA/ROCK1/PTEN/LIMS1/CORO1C/DUSP22	7
GO:0071300	cellular response to retinoic acid	7/896	66/18722	0.0378306334930419	0.110776048480721	LYN/KLF4/PTK2B/SETX/TWF2/ATM/CREB1	7
GO:0090109	regulation of cell-substrate junction assembly	7/896	66/18722	0.0378306334930419	0.110776048480721	IQGAP1/RHOA/ROCK1/PTEN/LIMS1/CORO1C/DUSP22	7
GO:0043547	positive regulation of GTPase activity	19/896	255/18722	0.0378937341501403	0.110776048480721	CCL3L3/CCL3/DOCK11/GPR65/CCL4/RASGRP2/PREX1/PTK2B/RHOG/RGS10/ARAP1/ADAP2/RAP1A/PICALM/DOCK8/LIMS1/CORO1C/RABGAP1L/SNX18	19
GO:1903362	regulation of cellular protein catabolic process	19/896	255/18722	0.0378937341501403	0.110776048480721	LAPTM5/LRRK2/MSN/TNFAIP3/GPX1/PTK2B/HSPA1A/FBXL5/PSME2/AGTPBP1/TRIB1/PSME1/GABARAP/PRKACA/SDCBP/PTEN/PIAS1/WAC/HERPUD1	19
GO:0048259	regulation of receptor-mediated endocytosis	10/896	110/18722	0.0379998233662001	0.110776048480721	B2M/ARRB2/PPT1/SYK/NUMB/RIN3/ANKRD13D/PICALM/SDCBP/BMP2K	10
GO:0090174	organelle membrane fusion	10/896	110/18722	0.0379998233662001	0.110776048480721	CORO1A/STX11/SAMD9/STX10/RAB8B/CHP1/PIP4K2A/GNAI3/STX7/STX12	10
GO:0036473	cell death in response to oxidative stress	9/896	95/18722	0.0380384355652934	0.110776048480721	SOD2/MCL1/LRRK2/CYP1B1/GPX1/JAK2/TLR4/FYN/HIF1A	9
GO:0010758	regulation of macrophage chemotaxis	4/896	27/18722	0.0380634297402055	0.110776048480721	C5AR1/CSF1R/PTK2B/MAPK1	4
GO:0034453	microtubule anchoring	4/896	27/18722	0.0380634297402055	0.110776048480721	NIN/BICD2/CEP350/HOOK3	4
GO:0039529	RIG-I signaling pathway	4/896	27/18722	0.0380634297402055	0.110776048480721	USP15/BIRC3/SEC14L1/BIRC2	4
GO:0002827	positive regulation of T-helper 1 type immune response	3/896	16/18722	0.0383807804964929	0.110776048480721	IL1B/SLC11A1/CCR2	3
GO:0002830	positive regulation of type 2 immune response	3/896	16/18722	0.0383807804964929	0.110776048480721	CD74/CD86/NLRP3	3
GO:0003084	positive regulation of systemic arterial blood pressure	3/896	16/18722	0.0383807804964929	0.110776048480721	CYBA/RHOA/WNK1	3
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	3/896	16/18722	0.0383807804964929	0.110776048480721	SP100/CDKN1A/ZNF385A	3
GO:0009048	dosage compensation by inactivation of X chromosome	3/896	16/18722	0.0383807804964929	0.110776048480721	XIST/SMCHD1/HNRNPU	3
GO:0010919	regulation of inositol phosphate biosynthetic process	3/896	16/18722	0.0383807804964929	0.110776048480721	PLEK/PTAFR/PTK2B	3
GO:0033631	cell-cell adhesion mediated by integrin	3/896	16/18722	0.0383807804964929	0.110776048480721	ITGA4/FERMT3/WNK1	3
GO:0034116	positive regulation of heterotypic cell-cell adhesion	3/896	16/18722	0.0383807804964929	0.110776048480721	IL1B/CD44/TNF	3
GO:0045779	negative regulation of bone resorption	3/896	16/18722	0.0383807804964929	0.110776048480721	TNFAIP3/CSK/INPP5D	3
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	3/896	16/18722	0.0383807804964929	0.110776048480721	IL1B/TNFRSF1B/TNF	3
GO:0060330	regulation of response to interferon-gamma	3/896	16/18722	0.0383807804964929	0.110776048480721	PARP9/PARP14/PTPN2	3
GO:0060334	regulation of interferon-gamma-mediated signaling pathway	3/896	16/18722	0.0383807804964929	0.110776048480721	PARP9/PARP14/PTPN2	3
GO:0072109	glomerular mesangium development	3/896	16/18722	0.0383807804964929	0.110776048480721	EGR1/IL6R/CFLAR	3
GO:0090336	positive regulation of brown fat cell differentiation	3/896	16/18722	0.0383807804964929	0.110776048480721	PTGS2/METRNL/HNRNPU	3
GO:0099010	modification of postsynaptic structure	3/896	16/18722	0.0383807804964929	0.110776048480721	RHOA/CDC42/PFN1	3
GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	3/896	16/18722	0.0383807804964929	0.110776048480721	CD74/CD44/ZNF385A	3
GO:1903236	regulation of leukocyte tethering or rolling	3/896	16/18722	0.0383807804964929	0.110776048480721	ITGA4/CCR2/PTAFR	3
GO:1905153	regulation of membrane invagination	3/896	16/18722	0.0383807804964929	0.110776048480721	CD36/NCKAP1L/CD300A	3
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	3/896	16/18722	0.0383807804964929	0.110776048480721	GLRX/CHP1/WNK1	3
GO:2000765	regulation of cytoplasmic translation	3/896	16/18722	0.0383807804964929	0.110776048480721	CNBP/ZNF385A/EEF2	3
GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	3/896	16/18722	0.0383807804964929	0.110776048480721	PARP9/SMCHD1/DTX3L	3
GO:2001224	positive regulation of neuron migration	3/896	16/18722	0.0383807804964929	0.110776048480721	FLNA/SHTN1/NIPBL	3
GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	3/896	16/18722	0.0383807804964929	0.110776048480721	PLAUR/JAK2/LGALS9	3
GO:0000422	autophagy of mitochondrion	8/896	81/18722	0.0396730946374425	0.114252361688449	TSPO/VPS13C/GABARAP/ATG3/BNIP3L/HIF1A/TOMM7/RB1CC1	8
GO:0006096	glycolytic process	8/896	81/18722	0.0396730946374425	0.114252361688449	FBP1/PRKAG2/STAT3/HIF1A/PGK1/ZBTB7A/ADPGK/EP300	8
GO:0060968	regulation of gene silencing	8/896	81/18722	0.0396730946374425	0.114252361688449	ZFP36/NEAT1/TGFB1/TNF/DDX5/STAT3/ADAR/PPP3CA	8
GO:0061726	mitochondrion disassembly	8/896	81/18722	0.0396730946374425	0.114252361688449	TSPO/VPS13C/GABARAP/ATG3/BNIP3L/HIF1A/TOMM7/RB1CC1	8
GO:0046390	ribose phosphate biosynthetic process	15/896	190/18722	0.0397124958071655	0.114302540505295	TMSB4X/PPT1/TGFB1/TKT/UPP1/ACSL1/PDK4/G6PD/PRKAG2/ELOVL5/ATP6V1A/STAT3/ADCY7/PYGL/ACSL4	15
GO:0007566	embryo implantation	6/896	53/18722	0.0401183995049596	0.115152205201598	IL1B/VMP1/ARHGDIB/TIMP1/PTGS2/TGFBR2	6
GO:0008347	glial cell migration	6/896	53/18722	0.0401183995049596	0.115152205201598	TSPO/CCL3/CX3CR1/CCR2/SUN2/MBOAT7	6
GO:0033059	cellular pigmentation	6/896	53/18722	0.0401183995049596	0.115152205201598	ZEB2/LYST/RAB32/RAB27A/BLOC1S1/BLOC1S6	6
GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	6/896	53/18722	0.0401183995049596	0.115152205201598	RGS2/PLEK/GNAI2/ARRB2/CXCL8/YWHAB	6
GO:0097479	synaptic vesicle localization	6/896	53/18722	0.0401183995049596	0.115152205201598	LRRK2/RAB27A/BLOC1S1/PICALM/PTEN/BLOC1S6	6
GO:0034620	cellular response to unfolded protein	9/896	96/18722	0.0402697921510521	0.115395696406403	SERP1/HSPA1A/PPP1R15A/PPP1R15B/ATF3/PTPN2/TMBIM6/EP300/HERPUD1	9
GO:0055017	cardiac muscle tissue growth	9/896	96/18722	0.0402697921510521	0.115395696406403	RGS2/MEF2C/AKAP13/G6PD/PAK1/PRKAR1A/PTEN/MAPK1/TGFBR2	9
GO:1901655	cellular response to ketone	9/896	96/18722	0.0402697921510521	0.115395696406403	KLF2/MSN/KLF4/AHR/CFLAR/NCOA4/GNB1/NR3C1/XRN1	9
GO:0061180	mammary gland epithelium development	7/896	67/18722	0.0405730430784553	0.116200659169078	CEBPB/GPX1/JAK2/CSF1R/STAT6/HIF1A/MAPK1	7
GO:0009394	2'-deoxyribonucleotide metabolic process	5/896	40/18722	0.0408732780694174	0.116803252329143	TYMP/SAMHD1/DPYD/UPP1/NUDT16	5
GO:0010863	positive regulation of phospholipase C activity	5/896	40/18722	0.0408732780694174	0.116803252329143	C5AR1/CD86/PTAFR/PLCB2/GNAQ	5
GO:0030501	positive regulation of bone mineralization	5/896	40/18722	0.0408732780694174	0.116803252329143	ISG15/MEF2C/TGFB1/SLC8A1/ALOX5	5
GO:2000781	positive regulation of double-strand break repair	5/896	40/18722	0.0408732780694174	0.116803252329143	ACTR2/WAS/PARP9/SMCHD1/DTX3L	5
GO:0062013	positive regulation of small molecule metabolic process	12/896	143/18722	0.0418338842200213	0.119482719290681	IL1B/TMSB4X/CD74/PTGS2/TNF/LPGAT1/PTAFR/ELOVL5/STAT3/HIF1A/IRS2/PTPN2	12
GO:0000956	nuclear-transcribed mRNA catabolic process	10/896	112/18722	0.0421768510422715	0.120393776766881	ZFP36/ZFP36L2/BTG2/PABPC1/ZFP36L1/DDX5/ATM/XRN2/XRN1/SMG1	10
GO:0006757	ATP generation from ADP	8/896	82/18722	0.0421991645925829	0.120393776766881	FBP1/PRKAG2/STAT3/HIF1A/PGK1/ZBTB7A/ADPGK/EP300	8
GO:0043255	regulation of carbohydrate biosynthetic process	9/896	97/18722	0.0425880784844146	0.121436730371404	PLEK/TGFB1/PTAFR/PTK2B/FBP1/IRS2/PTPN2/EP300/NFKB1	9
GO:0000303	response to superoxide	4/896	28/18722	0.0427832170506856	0.121526767821199	SOD2/CD36/UCP2/GCH1	4
GO:0006972	hyperosmotic response	4/896	28/18722	0.0427832170506856	0.121526767821199	RCSD1/PKN1/HNMT/MICU1	4
GO:0032958	inositol phosphate biosynthetic process	4/896	28/18722	0.0427832170506856	0.121526767821199	PLEK/PTAFR/PTK2B/PPIP5K2	4
GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	4/896	28/18722	0.0427832170506856	0.121526767821199	SOCS3/SH2B3/PARP14/PTPN2	4
GO:0060765	regulation of androgen receptor signaling pathway	4/896	28/18722	0.0427832170506856	0.121526767821199	PKN1/DDX5/ZBTB7A/EP300	4
GO:0090200	positive regulation of release of cytochrome c from mitochondria	4/896	28/18722	0.0427832170506856	0.121526767821199	PYCARD/TNFSF10/PLAUR/BID	4
GO:1903649	regulation of cytoplasmic transport	4/896	28/18722	0.0427832170506856	0.121526767821199	LRRK2/MSN/SORL1/MAPK1	4
GO:0006584	catecholamine metabolic process	6/896	54/18722	0.0433819009681333	0.122824859518379	ITGB2/NR4A2/SULT1A1/ITGAM/GCH1/MTPN	6
GO:0009712	catechol-containing compound metabolic process	6/896	54/18722	0.0433819009681333	0.122824859518379	ITGB2/NR4A2/SULT1A1/ITGAM/GCH1/MTPN	6
GO:0010659	cardiac muscle cell apoptotic process	6/896	54/18722	0.0433819009681333	0.122824859518379	JAK2/APAF1/CAPN2/CFLAR/PTEN/GNB1	6
GO:0043647	inositol phosphate metabolic process	6/896	54/18722	0.0433819009681333	0.122824859518379	PLEK/PTAFR/PTK2B/PTEN/NUDT3/PPIP5K2	6
GO:0072698	protein localization to microtubule cytoskeleton	6/896	54/18722	0.0433819009681333	0.122824859518379	SNX10/DIAPH1/CEP350/HNRNPU/NUP62/HOOK3	6
GO:2000179	positive regulation of neural precursor cell proliferation	6/896	54/18722	0.0433819009681333	0.122824859518379	LYN/FLNA/GNAI2/CX3CR1/CTSZ/HIF1A	6
GO:0010812	negative regulation of cell-substrate adhesion	7/896	68/18722	0.0434416542823504	0.12286027401985	LGALS1/GBP1/RHOA/BCL6/PTEN/CORO1C/DUSP22	7
GO:0032922	circadian regulation of gene expression	7/896	68/18722	0.0434416542823504	0.12286027401985	NAMPT/EGR1/AHR/MYCBP2/HNRNPU/KMT2A/KDM5A	7
GO:0007612	learning	12/896	144/18722	0.0437415685405062	0.123574089070708	FOS/BTG2/PTGS2/ACTR2/PPT1/TLR2/NRGN/FYN/JUN/HIF1A/PIAS1/CREB1	12
GO:0014065	phosphatidylinositol 3-kinase signaling	12/896	144/18722	0.0437415685405062	0.123574089070708	NCF1/HCST/KLF4/FGR/PTPN6/JAK2/PIK3AP1/TNF/FYN/ZFP36L1/HCLS1/PTEN	12
GO:0090150	establishment of protein localization to membrane	19/896	260/18722	0.0446373993092495	0.126018296051068	ITGB2/NCF1/VAMP5/RILPL2/BID/CSK/ITGAM/FYN/RAB8B/CHP1/PAK1/ATG3/SDCBP/ZDHHC20/OXA1L/SSR1/RAB10/PRNP/CIB1	19
GO:0050886	endocrine process	8/896	83/18722	0.0448294286091632	0.126018296051068	IL1B/CYBA/RETN/CTSZ/RHOA/RAB8B/RAB11FIP1/ATP6AP2	8
GO:0008334	histone mRNA metabolic process	3/896	17/18722	0.0449931098158065	0.126018296051068	ATM/LSM10/XRN1	3
GO:0014856	skeletal muscle cell proliferation	3/896	17/18722	0.0449931098158065	0.126018296051068	JAK2/STAT3/CFLAR	3
GO:0036035	osteoclast development	3/896	17/18722	0.0449931098158065	0.126018296051068	TYROBP/LILRB1/NOTCH2	3
GO:0038065	collagen-activated signaling pathway	3/896	17/18722	0.0449931098158065	0.126018296051068	JAK2/SYK/OSCAR	3
GO:0042053	regulation of dopamine metabolic process	3/896	17/18722	0.0449931098158065	0.126018296051068	ITGB2/NR4A2/ITGAM	3
GO:0042069	regulation of catecholamine metabolic process	3/896	17/18722	0.0449931098158065	0.126018296051068	ITGB2/NR4A2/ITGAM	3
GO:0042772	DNA damage response, signal transduction resulting in transcription	3/896	17/18722	0.0449931098158065	0.126018296051068	SP100/CDKN1A/ZNF385A	3
GO:0042953	lipoprotein transport	3/896	17/18722	0.0449931098158065	0.126018296051068	VMP1/CD36/PRKCB	3
GO:0044539	long-chain fatty acid import into cell	3/896	17/18722	0.0449931098158065	0.126018296051068	CD36/ACSL1/IRS2	3
GO:0045198	establishment of epithelial cell apical/basal polarity	3/896	17/18722	0.0449931098158065	0.126018296051068	MSN/RHOA/CDC42	3
GO:0061158	3'-UTR-mediated mRNA destabilization	3/896	17/18722	0.0449931098158065	0.126018296051068	ZFP36/ZFP36L2/ZFP36L1	3
GO:0140354	lipid import into cell	3/896	17/18722	0.0449931098158065	0.126018296051068	CD36/ACSL1/IRS2	3
GO:2000811	negative regulation of anoikis	3/896	17/18722	0.0449931098158065	0.126018296051068	MCL1/PDK4/ITGA5	3
GO:1904029	regulation of cyclin-dependent protein kinase activity	9/896	98/18722	0.0449944194898738	0.126018296051068	ACTB/TNFAIP3/CCNL1/HHEX/CCNI/CDKN1A/CCNY/PTEN/ADAM17	9
GO:0007498	mesoderm development	11/896	129/18722	0.045346332586845	0.12693556285478	KLF4/HCK/SECTM1/JAK2/IKZF1/BTK/ZFP36L1/PRKACA/PRKAR1A/KDM6B/ETS2	11
GO:0007269	neurotransmitter secretion	12/896	145/18722	0.0457087500142675	0.127812477862476	STXBP2/LRRK2/NR4A1/MEF2C/PPT1/PRKCB/STX11/MCTP1/RAP1A/RAP1B/CTBP2/BLOC1S6	12
GO:0099643	signal release from synapse	12/896	145/18722	0.0457087500142675	0.127812477862476	STXBP2/LRRK2/NR4A1/MEF2C/PPT1/PRKCB/STX11/MCTP1/RAP1A/RAP1B/CTBP2/BLOC1S6	12
GO:0048638	regulation of developmental growth	23/896	330/18722	0.0462774157749679	0.12933306794498	RGS2/DUSP6/PLAC8/MEF2C/CXCR4/ARHGAP4/SERP1/DPYSL2/STK4/G6PD/SHTN1/PAK1/TWF2/CDKN1A/ITSN2/STAT3/PTEN/MAPK1/NIPBL/DBNL/TGFBR2/CELF1/CREB1	23
GO:0007409	axonogenesis	28/896	418/18722	0.0463844898038228	0.129562691444513	S100A6/ACTB/RAC2/ITGA4/NR4A2/VASP/NOTCH2/NUMB/PLXNC1/FYN/ARHGAP4/RHOG/DPYSL2/SKIL/NIN/C9orf72/SHTN1/PICALM/PAK1/PAK2/TWF2/PTEN/PLXNB2/DBNL/MYCBP2/RAB10/EMB/CREB1	28
GO:0060193	positive regulation of lipase activity	7/896	69/18722	0.0464379326093453	0.129642344337737	C5AR1/CD86/RHOA/PTAFR/PLCB2/GNAQ/GNA13	7
GO:0019751	polyol metabolic process	10/896	114/18722	0.0466566331768966	0.130113216704042	PLEK/PTAFR/GCH1/PTK2B/SPTLC2/NAAA/PTEN/ASAH1/NUDT3/PPIP5K2	10
GO:0051261	protein depolymerization	10/896	114/18722	0.0466566331768966	0.130113216704042	PLEK/CAPG/CFL1/CAPZA1/MTPN/CAPZA2/TWF2/FLII/TAOK1/CIB1	10
GO:0000768	syncytium formation by plasma membrane fusion	6/896	55/18722	0.0468069484866026	0.130322772526135	TYROBP/PLEKHO1/CD53/CAPN2/CFLAR/MYH9	6
GO:0048016	inositol phosphate-mediated signaling	6/896	55/18722	0.0468069484866026	0.130322772526135	CLEC7A/TNF/CHP1/PPP3CA/PRNP/CIB1	6
GO:0140253	cell-cell fusion	6/896	55/18722	0.0468069484866026	0.130322772526135	TYROBP/PLEKHO1/CD53/CAPN2/CFLAR/MYH9	6
GO:0006091	generation of precursor metabolites and energy	32/896	490/18722	0.0469527927136996	0.130658895079696	CYBB/CYBA/NCF1/NCF2/ALDH2/SCO2/TKT/BID/RHOA/FBP1/CYB5R4/BLOC1S1/G6PD/PGLS/PRKAG2/CHCHD10/STAT3/PGD/HIF1A/PGK1/PYGL/TALDO1/ZBTB7A/ADPGK/NQO2/OXA1L/IRS2/ME2/PLEC/EP300/RB1CC1/IFNAR1	32
GO:0060291	long-term synaptic potentiation	9/896	99/18722	0.0474898641374944	0.13200476220625	TYROBP/LILRB2/CX3CR1/NRGN/PTK2B/PTEN/MAPK1/PRNP/CREB1	9
GO:0051028	mRNA transport	11/896	130/18722	0.0474968653982936	0.13200476220625	ZFP36/NUP214/MX2/HHEX/ZFP36L1/BICD2/NUP50/QKI/MVP/NUP62/SMG1	11
GO:1900542	regulation of purine nucleotide metabolic process	8/896	84/18722	0.0475651008232958	0.13200476220625	TMSB4X/FBP1/PDK4/PRKAG2/STAT3/HIF1A/ZBTB7A/EP300	8
GO:0007043	cell-cell junction assembly	12/896	146/18722	0.0477361223962663	0.13200476220625	IL1B/ACTB/MTDH/PECAM1/TNF/GPBAR1/RHOA/TLN1/PAK2/PRKACA/ROCK1/HIPK1	12
GO:0000305	response to oxygen radical	4/896	29/18722	0.0478171451637328	0.13200476220625	SOD2/CD36/UCP2/GCH1	4
GO:0019359	nicotinamide nucleotide biosynthetic process	4/896	29/18722	0.0478171451637328	0.13200476220625	NAMPT/PARP9/KYNU/NADK	4
GO:0019363	pyridine nucleotide biosynthetic process	4/896	29/18722	0.0478171451637328	0.13200476220625	NAMPT/PARP9/KYNU/NADK	4
GO:0033028	myeloid cell apoptotic process	4/896	29/18722	0.0478171451637328	0.13200476220625	MEF2C/IRF7/PTEN/ADAM17	4
GO:0034067	protein localization to Golgi apparatus	4/896	29/18722	0.0478171451637328	0.13200476220625	VPS13C/GBP5/SORL1/BICD2	4
GO:0034311	diol metabolic process	4/896	29/18722	0.0478171451637328	0.13200476220625	GCH1/SPTLC2/NAAA/ASAH1	4
GO:0048679	regulation of axon regeneration	4/896	29/18722	0.0478171451637328	0.13200476220625	FLNA/KLF4/GRN/PTEN	4
GO:0095500	acetylcholine receptor signaling pathway	4/896	29/18722	0.0478171451637328	0.13200476220625	GNAI2/RGS10/GNAQ/GNB1	4
GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	4/896	29/18722	0.0478171451637328	0.13200476220625	SOD2/MCL1/GPX1/HIF1A	4
GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	4/896	29/18722	0.0478171451637328	0.13200476220625	CD74/CD44/BID/ZNF385A	4
GO:1902430	negative regulation of amyloid-beta formation	4/896	29/18722	0.0478171451637328	0.13200476220625	SORL1/RTN3/ROCK1/PRNP	4
GO:0007212	dopamine receptor signaling pathway	5/896	42/18722	0.0489201030004202	0.134478570668703	LRRK2/FLNA/ARRB2/GNB1/GNAI3	5
GO:0007520	myoblast fusion	5/896	42/18722	0.0489201030004202	0.134478570668703	PLEKHO1/CD53/CAPN2/CFLAR/MYH9	5
GO:0010677	negative regulation of cellular carbohydrate metabolic process	5/896	42/18722	0.0489201030004202	0.134478570668703	PLEK/FBP1/MIDN/STAT3/EP300	5
GO:0014912	negative regulation of smooth muscle cell migration	5/896	42/18722	0.0489201030004202	0.134478570668703	AIF1/MEF2C/RHOA/TRIB1/GNA13	5
GO:0019692	deoxyribose phosphate metabolic process	5/896	42/18722	0.0489201030004202	0.134478570668703	TYMP/SAMHD1/DPYD/UPP1/NUDT16	5
GO:0045687	positive regulation of glial cell differentiation	5/896	42/18722	0.0489201030004202	0.134478570668703	TNFRSF1B/TLR2/TGFB1/CXCR4/DICER1	5
GO:0048489	synaptic vesicle transport	5/896	42/18722	0.0489201030004202	0.134478570668703	LRRK2/RAB27A/BLOC1S1/PICALM/BLOC1S6	5
GO:1900274	regulation of phospholipase C activity	5/896	42/18722	0.0489201030004202	0.134478570668703	C5AR1/CD86/PTAFR/PLCB2/GNAQ	5
GO:0001649	osteoblast differentiation	17/896	229/18722	0.04898497667411	0.134585770566321	VCAN/JUNB/CCL3/MEF2C/CEBPB/RASSF2/TNF/TCIRG1/IL6R/JUND/PRKACA/DDX5/CLIC1/ADAR/HNRNPU/DDX21/NBR1	17
GO:0050657	nucleic acid transport	13/896	163/18722	0.0494986330720882	0.135781851586461	ZFP36/NUP214/MX2/HHEX/ZFP36L1/BICD2/YBX1/TGFBR2/NUP50/QKI/MVP/NUP62/SMG1	13
GO:0050658	RNA transport	13/896	163/18722	0.0494986330720882	0.135781851586461	ZFP36/NUP214/MX2/HHEX/ZFP36L1/BICD2/YBX1/TGFBR2/NUP50/QKI/MVP/NUP62/SMG1	13
GO:0072331	signal transduction by p53 class mediator	13/896	163/18722	0.0494986330720882	0.135781851586461	CD74/PYCARD/CD44/IFI16/SP100/SGK1/CDKN1A/DDX5/ZNF385A/ATM/MDM4/HIPK1/EP300	13
GO:0070830	bicellular tight junction assembly	7/896	70/18722	0.0495631682502786	0.135887210368845	MTDH/PECAM1/TNF/GPBAR1/PAK2/PRKACA/ROCK1	7
GO:0061640	cytoskeleton-dependent cytokinesis	9/896	100/18722	0.0500753834148795	0.137219214510426	RHOB/ACTR2/RHOA/ACTR3/ROCK1/PLEC/CHMP1B/NUP62/SNX18	9
GO:0002090	regulation of receptor internalization	6/896	56/18722	0.0503948724545357	0.137476806851763	ARRB2/SYK/NUMB/RIN3/ANKRD13D/SDCBP	6
GO:0010332	response to gamma radiation	6/896	56/18722	0.0503948724545357	0.137476806851763	CYBA/PTPRC/EGR1/GPX1/CDKN1A/ATM	6
GO:0010518	positive regulation of phospholipase activity	6/896	56/18722	0.0503948724545357	0.137476806851763	C5AR1/CD86/PTAFR/PLCB2/GNAQ/GNA13	6
GO:0010658	striated muscle cell apoptotic process	6/896	56/18722	0.0503948724545357	0.137476806851763	JAK2/APAF1/CAPN2/CFLAR/PTEN/GNB1	6
GO:0043470	regulation of carbohydrate catabolic process	6/896	56/18722	0.0503948724545357	0.137476806851763	FBP1/PRKAG2/STAT3/HIF1A/ZBTB7A/EP300	6
GO:0048255	mRNA stabilization	6/896	56/18722	0.0503948724545357	0.137476806851763	ZFP36/SLC11A1/PABPC1/MYD88/YBX1/HNRNPU	6
GO:0071385	cellular response to glucocorticoid stimulus	6/896	56/18722	0.0503948724545357	0.137476806851763	ZFP36/ZFP36L2/ZFP36L1/CFLAR/HNRNPU/NR3C1	6
GO:1904645	response to amyloid-beta	6/896	56/18722	0.0503948724545357	0.137476806851763	NAMPT/CD36/ITGA4/TLR4/FYN/PRNP	6
GO:0055013	cardiac muscle cell development	8/896	85/18722	0.0504072814201714	0.137476806851763	RGS2/SLC8A1/AKAP13/MEF2A/G6PD/PAK1/HNRNPU/PLEC	8
GO:0016197	endosomal transport	17/896	230/18722	0.0506497963652768	0.138065823320652	LRRK2/LYST/WAS/ACAP2/SORL1/STX10/BLOC1S1/PICALM/ITSN2/TMEM50A/CORO1C/LAMTOR1/RAB10/SNX2/CHMP1B/CMTM6/SNX18	17
GO:0030518	intracellular steroid hormone receptor signaling pathway	10/896	116/18722	0.0514463691307001	0.140163732765202	JAK2/RHOA/PKN1/PAK1/DDX5/NCOA4/ZBTB7A/ARID1A/NR3C1/EP300	10
GO:0070507	regulation of microtubule cytoskeleton organization	12/896	148/18722	0.051974054924666	0.14040629142129	RHOA/HSPA1A/NIN/PAK1/ROCK1/CYLD/BICD2/HNRNPU/TAOK1/CHMP1B/NUP62/CIB1	12
GO:0035264	multicellular organism growth	11/896	132/18722	0.052003577420808	0.14040629142129	KLF2/PLAC8/NOTCH2/ZFP36L1/STAT3/NIPBL/CELF1/TAF10/PLEC/EP300/CREB1	11
GO:0045667	regulation of osteoblast differentiation	11/896	132/18722	0.052003577420808	0.14040629142129	MEF2C/CEBPB/RASSF2/TNF/TCIRG1/IL6R/JUND/PRKACA/DDX5/CLIC1/NBR1	11
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	3/896	18/18722	0.0521293114275161	0.14040629142129	PTPRC/PTPN6/TNF	3
GO:0006595	polyamine metabolic process	3/896	18/18722	0.0521293114275161	0.14040629142129	OAZ1/SAT1/SAT2	3
GO:0007549	dosage compensation	3/896	18/18722	0.0521293114275161	0.14040629142129	XIST/SMCHD1/HNRNPU	3
GO:0009125	nucleoside monophosphate catabolic process	3/896	18/18722	0.0521293114275161	0.14040629142129	TYMP/DPYD/UPP1	3
GO:0030730	sequestering of triglyceride	3/896	18/18722	0.0521293114275161	0.14040629142129	IL1B/TNF/OSBPL8	3
GO:0031643	positive regulation of myelination	3/896	18/18722	0.0521293114275161	0.14040629142129	TNFRSF1B/ITGAX/DICER1	3
GO:0031649	heat generation	3/896	18/18722	0.0521293114275161	0.14040629142129	IL1B/PTGS2/TNF	3
GO:0036499	PERK-mediated unfolded protein response	3/896	18/18722	0.0521293114275161	0.14040629142129	PPP1R15A/PPP1R15B/PTPN2	3
GO:0043217	myelin maintenance	3/896	18/18722	0.0521293114275161	0.14040629142129	CXCR4/PTEN/PLEC	3
GO:0044247	cellular polysaccharide catabolic process	3/896	18/18722	0.0521293114275161	0.14040629142129	AOAH/PYGL/RB1CC1	3
GO:0044872	lipoprotein localization	3/896	18/18722	0.0521293114275161	0.14040629142129	VMP1/CD36/PRKCB	3
GO:0046851	negative regulation of bone remodeling	3/896	18/18722	0.0521293114275161	0.14040629142129	TNFAIP3/CSK/INPP5D	3
GO:0051895	negative regulation of focal adhesion assembly	3/896	18/18722	0.0521293114275161	0.14040629142129	PTEN/CORO1C/DUSP22	3
GO:0055070	copper ion homeostasis	3/896	18/18722	0.0521293114275161	0.14040629142129	SCO2/SLC31A2/PRNP	3
GO:0110154	RNA decapping	3/896	18/18722	0.0521293114275161	0.14040629142129	ZFP36/NUDT16/NUDT3	3
GO:0150079	negative regulation of neuroinflammatory response	3/896	18/18722	0.0521293114275161	0.14040629142129	PTPRC/TNFRSF1B/GRN	3
GO:0150118	negative regulation of cell-substrate junction organization	3/896	18/18722	0.0521293114275161	0.14040629142129	PTEN/CORO1C/DUSP22	3
GO:1901673	regulation of mitotic spindle assembly	3/896	18/18722	0.0521293114275161	0.14040629142129	HSPA1A/HNRNPU/CHMP1B	3
GO:1902001	fatty acid transmembrane transport	3/896	18/18722	0.0521293114275161	0.14040629142129	CD36/ACSL1/IRS2	3
GO:1905952	regulation of lipid localization	14/896	181/18722	0.0527053902491842	0.141884438243275	IL1B/TSPO/NFKBIA/CD36/RETN/SYK/TNF/ACSL1/OSBPL8/RXRA/LAMTOR1/IRS2/PTPN2/NFKB1	14
GO:0033555	multicellular organismal response to stress	7/896	71/18722	0.0528184736869385	0.142041820913013	TSPO/MEF2C/NR4A2/GCH1/CAPN2/PTEN/PPP3CA	7
GO:0150116	regulation of cell-substrate junction organization	7/896	71/18722	0.0528184736869385	0.142041820913013	IQGAP1/RHOA/ROCK1/PTEN/LIMS1/CORO1C/DUSP22	7
GO:0007202	activation of phospholipase C activity	4/896	30/18722	0.0531639835027867	0.142223260046232	C5AR1/CD86/PLCB2/GNAQ	4
GO:0043032	positive regulation of macrophage activation	4/896	30/18722	0.0531639835027867	0.142223260046232	CCL3/LRRK2/TLR4/JUND	4
GO:0044030	regulation of DNA methylation	4/896	30/18722	0.0531639835027867	0.142223260046232	SPI1/KDM1B/MBD2/KMT2A	4
GO:0048147	negative regulation of fibroblast proliferation	4/896	30/18722	0.0531639835027867	0.142223260046232	IFI30/FTH1/CD300A/MORC3	4
GO:0051125	regulation of actin nucleation	4/896	30/18722	0.0531639835027867	0.142223260046232	CORO1A/GMFG/WAS/BRK1	4
GO:0051491	positive regulation of filopodium assembly	4/896	30/18722	0.0531639835027867	0.142223260046232	DOCK11/ARAP1/RHOQ/CDC42	4
GO:0051968	positive regulation of synaptic transmission, glutamatergic	4/896	30/18722	0.0531639835027867	0.142223260046232	PTGS2/CCR2/PTK2B/GLUL	4
GO:0060674	placenta blood vessel development	4/896	30/18722	0.0531639835027867	0.142223260046232	JUNB/SOCS3/NOTCH2/MAPK1	4
GO:1903579	negative regulation of ATP metabolic process	4/896	30/18722	0.0531639835027867	0.142223260046232	TSPO/RHOA/FBP1/STAT3	4
GO:2000637	positive regulation of gene silencing by miRNA	4/896	30/18722	0.0531639835027867	0.142223260046232	ZFP36/TGFB1/DDX5/STAT3	4
GO:0001709	cell fate determination	5/896	43/18722	0.0532687772678446	0.142223260046232	MCL1/KLF4/MEF2C/NOTCH2/CDC42	5
GO:0045776	negative regulation of blood pressure	5/896	43/18722	0.0532687772678446	0.142223260046232	SOD2/SCPEP1/PTAFR/GCH1/PRCP	5
GO:0046636	negative regulation of alpha-beta T cell activation	5/896	43/18722	0.0532687772678446	0.142223260046232	LILRB1/LGALS9/TNFRSF14/CD300A/BCL6	5
GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	5/896	43/18722	0.0532687772678446	0.142223260046232	IL1B/MCL1/TNF/FYN/HSPA1A	5
GO:0045921	positive regulation of exocytosis	8/896	86/18722	0.0533569544514763	0.142385592663996	ITGB2/FGR/HLA-F/SYK/ITGAM/RAB27A/PTAFR/SDCBP	8
GO:0006611	protein export from nucleus	6/896	57/18722	0.0541467085930354	0.144271020180521	IL1B/NUP214/TGFB1/SP100/CHP1/PRKACA	6
GO:0006949	syncytium formation	6/896	57/18722	0.0541467085930354	0.144271020180521	TYROBP/PLEKHO1/CD53/CAPN2/CFLAR/MYH9	6
GO:0010883	regulation of lipid storage	6/896	57/18722	0.0541467085930354	0.144271020180521	NFKBIA/CD36/TNF/OSBPL8/PTPN2/NFKB1	6
GO:0046887	positive regulation of hormone secretion	11/896	133/18722	0.0543611297004762	0.14476816977582	HLA-DRB1/RETN/JAK2/SERP1/GLUL/NADK/RAB8B/HIF1A/ACSL4/IRS2/CREB1	11
GO:0042246	tissue regeneration	7/896	72/18722	0.0562047818632644	0.149448400036216	GPX1/MTPN/CDKN1A/CFLAR/TGFBR2/PPP3CA/NINJ1	7
GO:0051057	positive regulation of small GTPase mediated signal transduction	7/896	72/18722	0.0562047818632644	0.149448400036216	NOTCH2/LPAR6/GPR65/AKAP13/ARHGEF3/SHOC2/DYNLT1	7
GO:0055021	regulation of cardiac muscle tissue growth	7/896	72/18722	0.0562047818632644	0.149448400036216	RGS2/MEF2C/G6PD/PAK1/PTEN/MAPK1/TGFBR2	7
GO:0050808	synapse organization	28/896	426/18722	0.056244543679759	0.1494777065296	SRGN/C5AR1/LRRK2/FLNA/ACTB/TUBA1A/LILRB2/ACTR2/MEF2C/CX3CR1/IL10RA/TLR2/TNF/ITGAM/RHOA/FYN/CFL1/CHCHD10/CDC42/SDCBP/PTEN/CAST/PFN1/ADAM10/PLXNB2/CTBP2/DBNL/PRNP	28
GO:0048041	focal adhesion assembly	8/896	87/18722	0.0564149859588387	0.149777612032629	IQGAP1/RHOA/PTK2B/ROCK1/PTEN/LIMS1/CORO1C/DUSP22	8
GO:0051262	protein tetramerization	8/896	87/18722	0.0564149859588387	0.149777612032629	SAMHD1/SOD2/B2M/HLA-DRB1/VASP/GBP5/STK4/OXA1L	8
GO:0061008	hepaticobiliary system development	12/896	150/18722	0.0564602629003687	0.14982134048205	TNFAIP3/CEBPB/UCP2/NOTCH2/SULF2/RAP1A/CFLAR/NIPBL/HMOX1/TAF10/RB1CC1/SP3	12
GO:0008277	regulation of G protein-coupled receptor signaling pathway	11/896	134/18722	0.0567889874375591	0.150616789221185	RGS2/PLEK/GNAI2/ARRB2/CXCL8/RGS18/RGS10/ROCK1/YWHAB/GIT2/DYNLT1	11
GO:0016570	histone modification	30/896	463/18722	0.0575630195428873	0.152591878003342	IL1B/SPI1/LRRK2/USP15/JAK2/PRKCB/USP3/KDM1B/BCL6/JMJD1C/PKN1/DTX3L/KMT2E/KDM6B/ARID4A/NIPBL/ATM/MSL3/TET2/PHF20L1/KDM7A/KMT2C/WAC/TAF10/CREBBP/EP300/KMT2A/KDM5A/TRIP12/EPC1	30
GO:0009262	deoxyribonucleotide metabolic process	5/896	44/18722	0.0578347595904647	0.152767183661761	TYMP/SAMHD1/DPYD/UPP1/NUDT16	5
GO:0032620	interleukin-17 production	5/896	44/18722	0.0578347595904647	0.152767183661761	NCKAP1L/TGFB1/MYD88/TLR4/PRNP	5
GO:0032660	regulation of interleukin-17 production	5/896	44/18722	0.0578347595904647	0.152767183661761	NCKAP1L/TGFB1/MYD88/TLR4/PRNP	5
GO:0050999	regulation of nitric-oxide synthase activity	5/896	44/18722	0.0578347595904647	0.152767183661761	IL1B/TNF/GCH1/PTK2B/HIF1A	5
GO:0060324	face development	5/896	44/18722	0.0578347595904647	0.152767183661761	ZFAND5/RRAS/MAPK1/NIPBL/EP300	5
GO:0060711	labyrinthine layer development	5/896	44/18722	0.0578347595904647	0.152767183661761	JUNB/SOCS3/ZFP36L1/GRB2/MAPK1	5
GO:1903214	regulation of protein targeting to mitochondrion	5/896	44/18722	0.0578347595904647	0.152767183661761	LRRK2/RAC2/BNIP3L/UBE2D3/TOMM7	5
GO:0034767	positive regulation of ion transmembrane transport	13/896	167/18722	0.0579169522172675	0.152906633747212	CTSS/TMSB4X/VMP1/FLNA/IFNGR2/CCR2/KCNE3/PTAFR/GLRX/CALM2/G6PD/CHP1/WNK1	13
GO:0007405	neuroblast proliferation	6/896	58/18722	0.0580631982998337	0.15298211466942	LRRK2/CX3CR1/NUMB/HIF1A/PLXNB2/RAB10	6
GO:0042743	hydrogen peroxide metabolic process	6/896	58/18722	0.0580631982998337	0.15298211466942	CYBA/SOD2/RAC2/GPX1/FYN/STAT3	6
GO:0044380	protein localization to cytoskeleton	6/896	58/18722	0.0580631982998337	0.15298211466942	SNX10/DIAPH1/CEP350/HNRNPU/NUP62/HOOK3	6
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	6/896	58/18722	0.0580631982998337	0.15298211466942	S100A9/S100A8/MCL1/BID/SKIL/PTPN2	6
GO:0009135	purine nucleoside diphosphate metabolic process	9/896	103/18722	0.0583808914785633	0.153508097360975	FBP1/NUDT16/PRKAG2/STAT3/HIF1A/PGK1/ZBTB7A/ADPGK/EP300	9
GO:0009179	purine ribonucleoside diphosphate metabolic process	9/896	103/18722	0.0583808914785633	0.153508097360975	FBP1/NUDT16/PRKAG2/STAT3/HIF1A/PGK1/ZBTB7A/ADPGK/EP300	9
GO:0014013	regulation of gliogenesis	9/896	103/18722	0.0583808914785633	0.153508097360975	IL1B/TSPO/TNFRSF1B/LYN/TLR2/TGFB1/CXCR4/TNF/DICER1	9
GO:0090277	positive regulation of peptide hormone secretion	9/896	103/18722	0.0583808914785633	0.153508097360975	HLA-DRB1/JAK2/SERP1/GLUL/NADK/RAB8B/HIF1A/ACSL4/IRS2	9
GO:1904064	positive regulation of cation transmembrane transport	12/896	151/18722	0.0587978499175897	0.1536565261194	CTSS/TMSB4X/VMP1/FLNA/IFNGR2/CCR2/KCNE3/GLRX/CALM2/G6PD/CHP1/WNK1	12
GO:0001516	prostaglandin biosynthetic process	4/896	31/18722	0.0588214080953135	0.1536565261194	IL1B/CD74/PTGS2/TBXAS1	4
GO:0030212	hyaluronan metabolic process	4/896	31/18722	0.0588214080953135	0.1536565261194	IL1B/CD44/TGFB1/NFKB1	4
GO:0031063	regulation of histone deacetylation	4/896	31/18722	0.0588214080953135	0.1536565261194	LRRK2/BCL6/NIPBL/KDM5A	4
GO:0033238	regulation of cellular amine metabolic process	4/896	31/18722	0.0588214080953135	0.1536565261194	ITGB2/SLC7A7/NR4A2/ITGAM	4
GO:0043171	peptide catabolic process	4/896	31/18722	0.0588214080953135	0.1536565261194	LTA4H/TPP1/CTSH/LNPEP	4
GO:0046457	prostanoid biosynthetic process	4/896	31/18722	0.0588214080953135	0.1536565261194	IL1B/CD74/PTGS2/TBXAS1	4
GO:0060148	positive regulation of posttranscriptional gene silencing	4/896	31/18722	0.0588214080953135	0.1536565261194	ZFP36/TGFB1/DDX5/STAT3	4
GO:0061099	negative regulation of protein tyrosine kinase activity	4/896	31/18722	0.0588214080953135	0.1536565261194	PTPRC/DUSP22/PTPN2/MVP	4
GO:0071480	cellular response to gamma radiation	4/896	31/18722	0.0588214080953135	0.1536565261194	CYBA/EGR1/CDKN1A/ATM	4
GO:0090162	establishment of epithelial cell polarity	4/896	31/18722	0.0588214080953135	0.1536565261194	MSN/RHOA/CYTH1/CDC42	4
GO:1905144	response to acetylcholine	4/896	31/18722	0.0588214080953135	0.1536565261194	GNAI2/RGS10/GNAQ/GNB1	4
GO:1905145	cellular response to acetylcholine	4/896	31/18722	0.0588214080953135	0.1536565261194	GNAI2/RGS10/GNAQ/GNB1	4
GO:0090257	regulation of muscle system process	18/896	252/18722	0.0593125262700574	0.154823617172646	AIF1/RGS2/TNFRSF1B/KLF4/PTGS2/NR4A1/SLC8A1/RHOA/PTAFR/CALM2/MEF2A/G6PD/PAK1/MTPN/PRKACA/TNFRSF1A/ROCK1/PPP3CA	18
GO:0050779	RNA destabilization	8/896	88/18722	0.0595821224017023	0.154823617172646	ZFP36/ZFP36L2/TNFRSF1B/BTG2/PABPC1/ZFP36L1/ROCK1/CELF1	8
GO:0070988	demethylation	7/896	73/18722	0.0597228449109695	0.154823617172646	APOBEC3A/KDM1B/JMJD1C/KDM6B/TET2/KDM7A/KDM5A	7
GO:0006670	sphingosine metabolic process	3/896	19/18722	0.0597742402004754	0.154823617172646	SPTLC2/NAAA/ASAH1	3
GO:0007039	protein catabolic process in the vacuole	3/896	19/18722	0.0597742402004754	0.154823617172646	TPP1/TCIRG1/LAMP2	3
GO:0008356	asymmetric cell division	3/896	19/18722	0.0597742402004754	0.154823617172646	ACTR2/ACTR3/RAB10	3
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	3/896	19/18722	0.0597742402004754	0.154823617172646	TYMP/DPYD/UPP1	3
GO:0010759	positive regulation of macrophage chemotaxis	3/896	19/18722	0.0597742402004754	0.154823617172646	C5AR1/CSF1R/MAPK1	3
GO:0031065	positive regulation of histone deacetylation	3/896	19/18722	0.0597742402004754	0.154823617172646	LRRK2/BCL6/NIPBL	3
GO:0032616	interleukin-13 production	3/896	19/18722	0.0597742402004754	0.154823617172646	HLA-E/LGALS9/LILRA5	3
GO:0032656	regulation of interleukin-13 production	3/896	19/18722	0.0597742402004754	0.154823617172646	HLA-E/LGALS9/LILRA5	3
GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	3/896	19/18722	0.0597742402004754	0.154823617172646	ACSL1/ELOVL5/ACSL4	3
GO:0070233	negative regulation of T cell apoptotic process	3/896	19/18722	0.0597742402004754	0.154823617172646	TSC22D3/DOCK8/HIF1A	3
GO:1900221	regulation of amyloid-beta clearance	3/896	19/18722	0.0597742402004754	0.154823617172646	TNF/IFNGR1/ROCK1	3
GO:1903975	regulation of glial cell migration	3/896	19/18722	0.0597742402004754	0.154823617172646	CCL3/CX3CR1/CCR2	3
GO:2000251	positive regulation of actin cytoskeleton reorganization	3/896	19/18722	0.0597742402004754	0.154823617172646	HCK/HCLS1/CDC42	3
GO:2000269	regulation of fibroblast apoptotic process	3/896	19/18722	0.0597742402004754	0.154823617172646	STK17B/BID/BTG1	3
GO:0016482	cytosolic transport	13/896	168/18722	0.0601634578659703	0.155754178377756	LAPTM5/CORO1A/LRRK2/MSN/FLNA/ACTR2/VPS13C/SORL1/STX10/MAPK1/PIP4K2A/SNX2/HOOK3	13
GO:0007369	gastrulation	14/896	185/18722	0.0610211442605731	0.157896005621513	ITGB2/DUSP1/KLF4/ITGA4/IL1RN/MYADM/MBP/ITGA5/PRKACA/PRKAR1A/KDM6B/TGFBR2/ETS2/WNK1	14
GO:0008643	carbohydrate transport	12/896	152/18722	0.0611990899991348	0.158277706158876	IL1B/SLC2A3/PRKCB/TNF/AQP9/OSBPL8/MEF2A/RAP1A/PRKAG2/RHOQ/IRS2/PEA15	12
GO:2001020	regulation of response to DNA damage stimulus	16/896	219/18722	0.0616064480644457	0.159252055856452	IER3/CD74/CD44/MCL1/ACTR2/WAS/BID/PARP9/SMCHD1/SKIL/DTX3L/DDX5/ZNF385A/ATM/SMG1/TRIP12	16
GO:0043401	steroid hormone mediated signaling pathway	11/896	136/18722	0.0618578678243092	0.159822538775078	JAK2/RHOA/PKN1/PAK1/DDX5/RXRA/NCOA4/ZBTB7A/ARID1A/NR3C1/EP300	11
GO:0051897	positive regulation of protein kinase B signaling	10/896	120/18722	0.0619799138000963	0.159978923907842	CCL3/ARRB2/MTDH/GPX1/CX3CR1/TGFB1/HBEGF/TNF/HCLS1/OSBPL8	10
GO:0071774	response to fibroblast growth factor	10/896	120/18722	0.0619799138000963	0.159978923907842	ZFP36/ZFP36L2/CD44/IER2/CXCL8/NR4A1/SULF2/ZFP36L1/SETX/SHOC2	10
GO:0032768	regulation of monooxygenase activity	6/896	59/18722	0.0621447900502935	0.160324927108917	IL1B/TNF/GCH1/PTK2B/HIF1A/NFKB1	6
GO:0051052	regulation of DNA metabolic process	24/896	359/18722	0.0625980501205645	0.161225199288674	DUSP1/PTPRC/SPI1/KLF4/ACTR2/ARRB2/WAS/TGFB1/STAT6/PARP9/KDM1B/BCL6/PTK2B/SMCHD1/DTX3L/CDKN1A/MAPK1/ATM/MBD2/HNRNPU/XRN1/KMT2A/SMG1/TRIP12	24
GO:0035384	thioester biosynthetic process	5/896	45/18722	0.062617747080008	0.161225199288674	PPT1/ACSL1/PDK4/ELOVL5/ACSL4	5
GO:0044088	regulation of vacuole organization	5/896	45/18722	0.062617747080008	0.161225199288674	LRRK2/GRN/RALB/C9orf72/PIP4K2A	5
GO:0071616	acyl-CoA biosynthetic process	5/896	45/18722	0.062617747080008	0.161225199288674	PPT1/ACSL1/PDK4/ELOVL5/ACSL4	5
GO:0030968	endoplasmic reticulum unfolded protein response	7/896	74/18722	0.063373233415726	0.162847918475885	SERP1/PPP1R15A/PPP1R15B/ATF3/PTPN2/EP300/HERPUD1	7
GO:0051881	regulation of mitochondrial membrane potential	7/896	74/18722	0.063373233415726	0.162847918475885	TSPO/LRRK2/CASP1/UCP2/BID/CLIC1/BNIP3L	7
GO:0120192	tight junction assembly	7/896	74/18722	0.063373233415726	0.162847918475885	MTDH/PECAM1/TNF/GPBAR1/PAK2/PRKACA/ROCK1	7
GO:1903201	regulation of oxidative stress-induced cell death	7/896	74/18722	0.063373233415726	0.162847918475885	SOD2/MCL1/LRRK2/GPX1/TLR4/FYN/HIF1A	7
GO:2001022	positive regulation of response to DNA damage stimulus	9/896	105/18722	0.0643824063686988	0.165359454579557	ACTR2/WAS/PARP9/SMCHD1/SKIL/DTX3L/DDX5/ZNF385A/ATM	9
GO:0010039	response to iron ion	4/896	32/18722	0.0647860654743308	0.165741429676338	B2M/G6PD/HIF1A/HMOX1	4
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	4/896	32/18722	0.0647860654743308	0.165741429676338	TNFAIP3/HHEX/CDKN1A/PTEN	4
GO:0051497	negative regulation of stress fiber assembly	4/896	32/18722	0.0647860654743308	0.165741429676338	WAS/ARAP1/PAK2/PFN1	4
GO:0060323	head morphogenesis	4/896	32/18722	0.0647860654743308	0.165741429676338	RRAS/ATP6AP2/NIPBL/EP300	4
GO:0072525	pyridine-containing compound biosynthetic process	4/896	32/18722	0.0647860654743308	0.165741429676338	NAMPT/PARP9/KYNU/NADK	4
GO:0097345	mitochondrial outer membrane permeabilization	4/896	32/18722	0.0647860654743308	0.165741429676338	BID/HSPA1A/CHCHD10/BNIP3L	4
GO:1901185	negative regulation of ERBB signaling pathway	4/896	32/18722	0.0647860654743308	0.165741429676338	PTPN18/PTPN2/MVP/NUP62	4
GO:2000191	regulation of fatty acid transport	4/896	32/18722	0.0647860654743308	0.165741429676338	IL1B/SYK/ACSL1/IRS2	4
GO:0043487	regulation of RNA stability	13/896	170/18722	0.0648298811110835	0.16577198213311	ZFP36/VIM/ZFP36L2/TNFRSF1B/SLC11A1/BTG2/PABPC1/MYD88/ZFP36L1/ROCK1/YBX1/HNRNPU/CELF1	13
GO:1903050	regulation of proteolysis involved in cellular protein catabolic process	16/896	221/18722	0.0657136342618057	0.167949194985578	LAPTM5/LRRK2/GPX1/PTK2B/HSPA1A/PSME2/AGTPBP1/TRIB1/PSME1/GABARAP/PRKACA/SDCBP/PTEN/PIAS1/WAC/HERPUD1	16
GO:1901888	regulation of cell junction assembly	15/896	204/18722	0.0657605349402785	0.167986513862666	IL1B/MEF2C/IQGAP1/TLR2/TNF/GPBAR1/RHOA/RAP1A/PRKACA/ROCK1/PTEN/LIMS1/RAP1B/CORO1C/DUSP22	15
GO:0034644	cellular response to UV	8/896	90/18722	0.0662460906970358	0.169060803589442	CRIP1/CARD16/TIMP1/PTGS2/CDKN1A/POLK/CREBBP/EP300	8
GO:0046031	ADP metabolic process	8/896	90/18722	0.0662460906970358	0.169060803589442	FBP1/PRKAG2/STAT3/HIF1A/PGK1/ZBTB7A/ADPGK/EP300	8
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	6/896	60/18722	0.066391641793666	0.169100356987687	MBNL1/CELF2/DDX5/ZBTB7A/HNRNPU/CELF1	6
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	6/896	60/18722	0.066391641793666	0.169100356987687	TAOK3/CDKN1A/ATM/NABP1/FOXN3/TAOK1	6
GO:0031102	neuron projection regeneration	6/896	60/18722	0.066391641793666	0.169100356987687	TSPO/FLNA/KLF4/JAK2/GRN/PTEN	6
GO:1903670	regulation of sprouting angiogenesis	6/896	60/18722	0.066391641793666	0.169100356987687	KLF2/KLF4/ALOX5/GLUL/JAK1/ITGA5	6
GO:0034976	response to endoplasmic reticulum stress	18/896	256/18722	0.0668661532043533	0.170225581407656	LRRK2/CXCL8/CEBPB/BID/ALOX5/JUN/SERP1/HSPA1A/PPP1R15A/PPP1R15B/ATF3/EEF2/PTPN2/TMBIM6/DDX3X/EP300/GRINA/HERPUD1	18
GO:0009185	ribonucleoside diphosphate metabolic process	9/896	106/18722	0.0675241859295516	0.171465458567907	FBP1/NUDT16/PRKAG2/STAT3/HIF1A/PGK1/ZBTB7A/ADPGK/EP300	9
GO:0090263	positive regulation of canonical Wnt signaling pathway	9/896	106/18722	0.0675241859295516	0.171465458567907	ZEB2/LRRK2/TGFB1/SULF2/HHEX/ATP6AP2/DDX3X/WNK1/NFKB1	9
GO:1905477	positive regulation of protein localization to membrane	9/896	106/18722	0.0675241859295516	0.171465458567907	ITGB2/TNF/ITGAM/FYN/RHOG/CHP1/PAK1/PRNP/CIB1	9
GO:2000278	regulation of DNA biosynthetic process	9/896	106/18722	0.0675241859295516	0.171465458567907	DUSP1/KLF4/ARRB2/PTK2B/CDKN1A/MAPK1/ATM/HNRNPU/XRN1	9
GO:0001974	blood vessel remodeling	5/896	46/18722	0.0676169304985151	0.171465458567907	CST3/FLNA/MEF2C/TGFB1/CCR2	5
GO:0010828	positive regulation of glucose transmembrane transport	5/896	46/18722	0.0676169304985151	0.171465458567907	OSBPL8/MEF2A/RAP1A/RHOQ/IRS2	5
GO:0033047	regulation of mitotic sister chromatid segregation	5/896	46/18722	0.0676169304985151	0.171465458567907	DUSP1/ATM/HNRNPU/ZNF207/DYNC1LI1	5
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	5/896	46/18722	0.0676169304985151	0.171465458567907	AIF1/KMT2E/LSM10/ADAM17/DDX3X	5
GO:0000272	polysaccharide catabolic process	3/896	20/18722	0.0679106116774693	0.171624436994421	AOAH/PYGL/RB1CC1	3
GO:0007097	nuclear migration	3/896	20/18722	0.0679106116774693	0.171624436994421	CDC42/SUN2/HOOK3	3
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	3/896	20/18722	0.0679106116774693	0.171624436994421	TYMP/DPYD/UPP1	3
GO:0016553	base conversion or substitution editing	3/896	20/18722	0.0679106116774693	0.171624436994421	APOBEC3A/NUDT16/ADAR	3
GO:0032495	response to muramyl dipeptide	3/896	20/18722	0.0679106116774693	0.171624436994421	VIM/NFKBIA/TNFAIP3	3
GO:0071243	cellular response to arsenic-containing substance	3/896	20/18722	0.0679106116774693	0.171624436994421	ATF3/HMOX1/DDX3X	3
GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	3/896	20/18722	0.0679106116774693	0.171624436994421	SOD2/GPX1/HIF1A	3
GO:0055006	cardiac cell development	8/896	91/18722	0.0697438076111134	0.176171706355221	RGS2/SLC8A1/AKAP13/MEF2A/G6PD/PAK1/HNRNPU/PLEC	8
GO:0071384	cellular response to corticosteroid stimulus	6/896	61/18722	0.0708036242870097	0.178440353642259	ZFP36/ZFP36L2/ZFP36L1/CFLAR/HNRNPU/NR3C1	6
GO:0090342	regulation of cell aging	6/896	61/18722	0.0708036242870097	0.178440353642259	NAMPT/B2M/BCL6/MAP3K3/PTEN/YBX1	6
GO:0010737	protein kinase A signaling	4/896	33/18722	0.0710536382220954	0.178440353642259	LCP1/LRRK2/PRKACA/PJA2	4
GO:0019362	pyridine nucleotide metabolic process	4/896	33/18722	0.0710536382220954	0.178440353642259	NAMPT/PARP9/KYNU/NADK	4
GO:0033198	response to ATP	4/896	33/18722	0.0710536382220954	0.178440353642259	CASP1/PTGS2/SLC8A1/PTEN	4
GO:0035025	positive regulation of Rho protein signal transduction	4/896	33/18722	0.0710536382220954	0.178440353642259	LPAR6/GPR65/AKAP13/ARHGEF3	4
GO:0046496	nicotinamide nucleotide metabolic process	4/896	33/18722	0.0710536382220954	0.178440353642259	NAMPT/PARP9/KYNU/NADK	4
GO:0061842	microtubule organizing center localization	4/896	33/18722	0.0710536382220954	0.178440353642259	NIN/SUN2/BICD2/ARPC5	4
GO:0070570	regulation of neuron projection regeneration	4/896	33/18722	0.0710536382220954	0.178440353642259	FLNA/KLF4/GRN/PTEN	4
GO:0071539	protein localization to centrosome	4/896	33/18722	0.0710536382220954	0.178440353642259	SNX10/CEP350/NUP62/HOOK3	4
GO:1903146	regulation of autophagy of mitochondrion	4/896	33/18722	0.0710536382220954	0.178440353642259	TSPO/VPS13C/BNIP3L/HIF1A	4
GO:1904030	negative regulation of cyclin-dependent protein kinase activity	4/896	33/18722	0.0710536382220954	0.178440353642259	TNFAIP3/HHEX/CDKN1A/PTEN	4
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	5/896	47/18722	0.0728310096152256	0.181850254925006	CYBA/SOD2/CTSZ/RHOA/ATP6AP2	5
GO:0010712	regulation of collagen metabolic process	5/896	47/18722	0.0728310096152256	0.181850254925006	VIM/CST3/ARRB2/TGFB1/RAP1A	5
GO:0010799	regulation of peptidyl-threonine phosphorylation	5/896	47/18722	0.0728310096152256	0.181850254925006	TGFB1/CALM2/PRKAG2/MAPK1/CAB39	5
GO:0031641	regulation of myelination	5/896	47/18722	0.0728310096152256	0.181850254925006	TYMP/TNFRSF1B/ITGAX/PTEN/DICER1	5
GO:0042311	vasodilation	5/896	47/18722	0.0728310096152256	0.181850254925006	RGS2/SOD2/KLF2/GPX1/GCH1	5
GO:0045581	negative regulation of T cell differentiation	5/896	47/18722	0.0728310096152256	0.181850254925006	FGL2/CD74/IRF1/BCL6/PTPN2	5
GO:0045601	regulation of endothelial cell differentiation	5/896	47/18722	0.0728310096152256	0.181850254925006	IL1B/TNF/BTG1/TNFRSF1A/ROCK1	5
GO:0045911	positive regulation of DNA recombination	5/896	47/18722	0.0728310096152256	0.181850254925006	PTPRC/ACTR2/WAS/TGFB1/STAT6	5
GO:0050798	activated T cell proliferation	5/896	47/18722	0.0728310096152256	0.181850254925006	PYCARD/LGALS9/FYN/PRKAR1A/PRNP	5
GO:0101023	vascular endothelial cell proliferation	5/896	47/18722	0.0728310096152256	0.181850254925006	MEF2C/ITGA4/STAT3/SP1/ADAM17	5
GO:0120163	negative regulation of cold-induced thermogenesis	5/896	47/18722	0.0728310096152256	0.181850254925006	TLR4/ALDH1A1/RB1/LNPEP/ADAM17	5
GO:1905562	regulation of vascular endothelial cell proliferation	5/896	47/18722	0.0728310096152256	0.181850254925006	MEF2C/ITGA4/STAT3/SP1/ADAM17	5
GO:0035249	synaptic transmission, glutamatergic	8/896	92/18722	0.073352398515539	0.183064215297178	LRRK2/PTGS2/MEF2C/CCR2/TNF/PTK2B/GLUL/DGKZ	8
GO:0009314	response to radiation	29/896	456/18722	0.0733961539216701	0.183085561892857	CYBA/FOS/DUSP1/PTPRC/SOD2/CRIP1/CARD16/NAMPT/TIMP1/EGR1/IFI16/RHOB/PTGS2/GPX1/JUN/JUND/GRB2/CDKN1A/POLK/GNAQ/HIF1A/TANK/NIPBL/PIAS1/ATM/NABP1/CREBBP/EP300/CREB1	29
GO:0009132	nucleoside diphosphate metabolic process	10/896	124/18722	0.0738161657610312	0.184045003894115	ENTPD1/FBP1/NUDT16/PRKAG2/STAT3/HIF1A/PGK1/ZBTB7A/ADPGK/EP300	10
GO:0048639	positive regulation of developmental growth	13/896	174/18722	0.0748664730970489	0.186574282020964	MEF2C/CXCR4/SERP1/SHTN1/PAK1/TWF2/ITSN2/MAPK1/NIPBL/DBNL/TGFBR2/CELF1/CREB1	13
GO:0046847	filopodium assembly	6/896	62/18722	0.0753803253080869	0.187674998529134	FGD2/DOCK11/FGD4/ARAP1/RHOQ/CDC42	6
GO:1902750	negative regulation of cell cycle G2/M phase transition	6/896	62/18722	0.0753803253080869	0.187674998529134	TAOK3/CDKN1A/ATM/NABP1/FOXN3/TAOK1	6
GO:0032355	response to estradiol	11/896	141/18722	0.0757947450141657	0.188436170563421	TXNIP/DUSP1/PTGS2/TGFB1/ARPC1B/BID/STAT3/CFLAR/PTEN/MBD2/EEF2	11
GO:0035296	regulation of tube diameter	11/896	141/18722	0.0757947450141657	0.188436170563421	RGS2/SOD2/KLF2/PTGS2/GPX1/SLC8A1/SCPEP1/RHOA/TBXAS1/GCH1/ROCK1	11
GO:0097746	blood vessel diameter maintenance	11/896	141/18722	0.0757947450141657	0.188436170563421	RGS2/SOD2/KLF2/PTGS2/GPX1/SLC8A1/SCPEP1/RHOA/TBXAS1/GCH1/ROCK1	11
GO:0003177	pulmonary valve development	3/896	21/18722	0.0765193546303194	0.188704202670598	TNFRSF1B/NOTCH2/TNFRSF1A	3
GO:0006244	pyrimidine nucleotide catabolic process	3/896	21/18722	0.0765193546303194	0.188704202670598	TYMP/DPYD/UPP1	3
GO:0006353	DNA-templated transcription, termination	3/896	21/18722	0.0765193546303194	0.188704202670598	SETX/XRN2/PCF11	3
GO:0034312	diol biosynthetic process	3/896	21/18722	0.0765193546303194	0.188704202670598	GCH1/SPTLC2/ASAH1	3
GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	3/896	21/18722	0.0765193546303194	0.188704202670598	GMFG/WAS/BRK1	3
GO:0042454	ribonucleoside catabolic process	3/896	21/18722	0.0765193546303194	0.188704202670598	APOBEC3A/CDA/UPP1	3
GO:0045056	transcytosis	3/896	21/18722	0.0765193546303194	0.188704202670598	FCGRT/PTAFR/PICALM	3
GO:0046519	sphingoid metabolic process	3/896	21/18722	0.0765193546303194	0.188704202670598	SPTLC2/NAAA/ASAH1	3
GO:0046597	negative regulation of viral entry into host cell	3/896	21/18722	0.0765193546303194	0.188704202670598	FCN1/IFITM3/IFITM2	3
GO:0046823	negative regulation of nucleocytoplasmic transport	3/896	21/18722	0.0765193546303194	0.188704202670598	CD36/SP100/CHP1	3
GO:0046885	regulation of hormone biosynthetic process	3/896	21/18722	0.0765193546303194	0.188704202670598	EGR1/HIF1A/NFKB1	3
GO:0048714	positive regulation of oligodendrocyte differentiation	3/896	21/18722	0.0765193546303194	0.188704202670598	TNFRSF1B/TLR2/CXCR4	3
GO:0050849	negative regulation of calcium-mediated signaling	3/896	21/18722	0.0765193546303194	0.188704202670598	PLEK/CHP1/PRNP	3
GO:0099515	actin filament-based transport	3/896	21/18722	0.0765193546303194	0.188704202670598	MYO1F/MYO1G/SUN2	3
GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	3/896	21/18722	0.0765193546303194	0.188704202670598	CD74/CD44/ZNF385A	3
GO:1902307	positive regulation of sodium ion transmembrane transport	3/896	21/18722	0.0765193546303194	0.188704202670598	GLRX/CHP1/WNK1	3
GO:1905209	positive regulation of cardiocyte differentiation	3/896	21/18722	0.0765193546303194	0.188704202670598	ARRB2/MEF2C/TGFB1	3
GO:0043488	regulation of mRNA stability	12/896	158/18722	0.0769659022928688	0.18971547764228	ZFP36/VIM/ZFP36L2/SLC11A1/BTG2/PABPC1/MYD88/ZFP36L1/ROCK1/YBX1/HNRNPU/CELF1	12
GO:0019217	regulation of fatty acid metabolic process	8/896	93/18722	0.0770719987959352	0.189797095519725	IL1B/CD74/PTGS2/LPGAT1/PDK4/PRKAG2/ELOVL5/IRS2	8
GO:0090398	cellular senescence	8/896	93/18722	0.0770719987959352	0.189797095519725	NAMPT/B2M/SPI1/BCL6/MAP3K3/CDKN1A/ATM/YBX1	8
GO:0009112	nucleobase metabolic process	4/896	34/18722	0.0776189114529352	0.190332842275679	TYMP/DPYD/CDA/MAPK1	4
GO:0010661	positive regulation of muscle cell apoptotic process	4/896	34/18722	0.0776189114529352	0.190332842275679	SOD2/CAPN2/STK4/PTEN	4
GO:0014072	response to isoquinoline alkaloid	4/896	34/18722	0.0776189114529352	0.190332842275679	AIF1/FOSB/CXCR4/PEA15	4
GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	4/896	34/18722	0.0776189114529352	0.190332842275679	CCL3/SLC8A1/CALM2/PRKACA	4
GO:0034383	low-density lipoprotein particle clearance	4/896	34/18722	0.0776189114529352	0.190332842275679	CD36/CSK/LIPA/HMOX1	4
GO:0043278	response to morphine	4/896	34/18722	0.0776189114529352	0.190332842275679	AIF1/FOSB/CXCR4/PEA15	4
GO:0048261	negative regulation of receptor-mediated endocytosis	4/896	34/18722	0.0776189114529352	0.190332842275679	RIN3/ANKRD13D/PICALM/SDCBP	4
GO:1904893	negative regulation of receptor signaling pathway via STAT	4/896	34/18722	0.0776189114529352	0.190332842275679	SOCS3/SH2B3/PARP14/PTPN2	4
GO:1990000	amyloid fibril formation	4/896	34/18722	0.0776189114529352	0.190332842275679	B2M/CD36/PFDN5/FKBP1A	4
GO:0090311	regulation of protein deacetylation	5/896	48/18722	0.0782582100156419	0.191719712807986	LRRK2/BCL6/NIPBL/EP300/KDM5A	5
GO:1905710	positive regulation of membrane permeability	5/896	48/18722	0.0782582100156419	0.191719712807986	LAPTM5/BID/HSPA1A/CHCHD10/BNIP3L	5
GO:0035150	regulation of tube size	11/896	142/18722	0.0788016724758616	0.191883297572522	RGS2/SOD2/KLF2/PTGS2/GPX1/SLC8A1/SCPEP1/RHOA/TBXAS1/GCH1/ROCK1	11
GO:0090559	regulation of membrane permeability	7/896	78/18722	0.079303102000763	0.191883297572522	LAPTM5/BID/HSPA1A/CHCHD10/BNIP3L/STAT3/DYNLT1	7
GO:0001820	serotonin secretion	2/896	10/18722	0.0797804307012157	0.191883297572522	LILRB1/SYK	2
GO:0002002	regulation of angiotensin levels in blood	2/896	10/18722	0.0797804307012157	0.191883297572522	CTSZ/ATP6AP2	2
GO:0002003	angiotensin maturation	2/896	10/18722	0.0797804307012157	0.191883297572522	CTSZ/ATP6AP2	2
GO:0002524	hypersensitivity	2/896	10/18722	0.0797804307012157	0.191883297572522	HLA-E/BTK	2
GO:0003330	regulation of extracellular matrix constituent secretion	2/896	10/18722	0.0797804307012157	0.191883297572522	TNFRSF1B/TNFRSF1A	2
GO:0010944	negative regulation of transcription by competitive promoter binding	2/896	10/18722	0.0797804307012157	0.191883297572522	HHEX/CREB1	2
GO:0010968	regulation of microtubule nucleation	2/896	10/18722	0.0797804307012157	0.191883297572522	HSPA1A/PAK1	2
GO:0016081	synaptic vesicle docking	2/896	10/18722	0.0797804307012157	0.191883297572522	CTBP2/BLOC1S6	2
GO:0030214	hyaluronan catabolic process	2/896	10/18722	0.0797804307012157	0.191883297572522	CD44/TGFB1	2
GO:0034085	establishment of sister chromatid cohesion	2/896	10/18722	0.0797804307012157	0.191883297572522	RB1/NIPBL	2
GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway	2/896	10/18722	0.0797804307012157	0.191883297572522	NAMPT/PARP9	2
GO:0035376	sterol import	2/896	10/18722	0.0797804307012157	0.191883297572522	CD36/LAMTOR1	2
GO:0035646	endosome to melanosome transport	2/896	10/18722	0.0797804307012157	0.191883297572522	RAB32/BLOC1S6	2
GO:0035747	natural killer cell chemotaxis	2/896	10/18722	0.0797804307012157	0.191883297572522	CCL3/CCL4	2
GO:0042368	vitamin D biosynthetic process	2/896	10/18722	0.0797804307012157	0.191883297572522	TNF/NFKB1	2
GO:0042711	maternal behavior	2/896	10/18722	0.0797804307012157	0.191883297572522	PTEN/MBD2	2
GO:0043485	endosome to pigment granule transport	2/896	10/18722	0.0797804307012157	0.191883297572522	RAB32/BLOC1S6	2
GO:0044557	relaxation of smooth muscle	2/896	10/18722	0.0797804307012157	0.191883297572522	RGS2/SLC8A1	2
GO:0045348	positive regulation of MHC class II biosynthetic process	2/896	10/18722	0.0797804307012157	0.191883297572522	JAK2/TLR4	2
GO:0045792	negative regulation of cell size	2/896	10/18722	0.0797804307012157	0.191883297572522	RHOA/PTEN	2
GO:0048757	pigment granule maturation	2/896	10/18722	0.0797804307012157	0.191883297572522	RAB32/BLOC1S6	2
GO:0051409	response to nitrosative stress	2/896	10/18722	0.0797804307012157	0.191883297572522	DUSP6/ATM	2
GO:0060439	trachea morphogenesis	2/896	10/18722	0.0797804307012157	0.191883297572522	MAPK1/TGFBR2	2
GO:0060736	prostate gland growth	2/896	10/18722	0.0797804307012157	0.191883297572522	PSAP/PTEN	2
GO:0070099	regulation of chemokine-mediated signaling pathway	2/896	10/18722	0.0797804307012157	0.191883297572522	SH2B3/HIF1A	2
GO:0070508	cholesterol import	2/896	10/18722	0.0797804307012157	0.191883297572522	CD36/LAMTOR1	2
GO:0071073	positive regulation of phospholipid biosynthetic process	2/896	10/18722	0.0797804307012157	0.191883297572522	CAPN2/CHP1	2
GO:0072203	cell proliferation involved in metanephros development	2/896	10/18722	0.0797804307012157	0.191883297572522	EGR1/STAT1	2
GO:0098885	modification of postsynaptic actin cytoskeleton	2/896	10/18722	0.0797804307012157	0.191883297572522	RHOA/PFN1	2
GO:0098903	regulation of membrane repolarization during action potential	2/896	10/18722	0.0797804307012157	0.191883297572522	FLNA/KCNE3	2
GO:1901725	regulation of histone deacetylase activity	2/896	10/18722	0.0797804307012157	0.191883297572522	LRRK2/KDM5A	2
GO:1903980	positive regulation of microglial cell activation	2/896	10/18722	0.0797804307012157	0.191883297572522	CCL3/LRRK2	2
GO:2000121	regulation of removal of superoxide radicals	2/896	10/18722	0.0797804307012157	0.191883297572522	CD36/GCH1	2
GO:2000510	positive regulation of dendritic cell chemotaxis	2/896	10/18722	0.0797804307012157	0.191883297572522	SPI1/LGALS9	2
GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	2/896	10/18722	0.0797804307012157	0.191883297572522	WAS/BRK1	2
GO:2001225	regulation of chloride transport	2/896	10/18722	0.0797804307012157	0.191883297572522	PTAFR/PRNP	2
GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	2/896	10/18722	0.0797804307012157	0.191883297572522	JAK2/LGALS9	2
GO:0007623	circadian rhythm	15/896	210/18722	0.0798007253699989	0.191883297572522	NAMPT/EGR1/JUN/AHR/SETX/JUND/GNAQ/PTEN/KLF10/MYCBP2/HNRNPU/EP300/KMT2A/KDM5A/CREB1	15
GO:0030239	myofibril assembly	6/896	63/18722	0.0801210546879045	0.19238670610886	AKAP13/MEF2A/PRKAR1A/CFLAR/FLII/PLEC	6
GO:0046902	regulation of mitochondrial membrane permeability	6/896	63/18722	0.0801210546879045	0.19238670610886	BID/HSPA1A/CHCHD10/BNIP3L/STAT3/DYNLT1	6
GO:1902373	negative regulation of mRNA catabolic process	6/896	63/18722	0.0801210546879045	0.19238670610886	ZFP36/SLC11A1/PABPC1/MYD88/YBX1/HNRNPU	6
GO:0031929	TOR signaling	10/896	126/18722	0.0802304687126033	0.192560529660475	NCKAP1L/CCDC88A/EIF4EBP1/LAMTOR4/C9orf72/HIF1A/ATM/LAMTOR1/WAC/SMG1	10
GO:0048511	rhythmic process	20/896	298/18722	0.0808516094103259	0.193961817593683	NAMPT/EGR1/ARRB2/RETN/JUN/AHR/SETX/JUND/DDX5/GNAQ/PTEN/KLF10/MYCBP2/HNRNPU/SP1/CREBBP/EP300/KMT2A/KDM5A/CREB1	20
GO:0007088	regulation of mitotic nuclear division	9/896	110/18722	0.0810393625750834	0.194322602467962	IL1B/DUSP1/CDC42/RB1/ATM/PHIP/NUP62/ZNF207/DYNC1LI1	9
GO:0034763	negative regulation of transmembrane transport	11/896	143/18722	0.0818823214971815	0.196253435072277	IL1B/RGS2/PRKCB/OAZ1/KCNE3/TNF/CALM2/PTEN/IRS2/CAB39/PEA15	11
GO:0043271	negative regulation of ion transport	12/896	160/18722	0.0827467373270577	0.198233892601579	RGS2/PTGS2/LILRB2/LILRB1/KCNE3/CD33/PTK2B/CALM2/PTEN/CAB39/TMBIM6/WNK1	12
GO:0030048	actin filament-based movement	10/896	127/18722	0.0835623755246364	0.200003642477512	FLNA/MYO1F/WAS/WIPF1/MYO1G/KCNE3/SHTN1/SUN2/MYO9B/MYH9	10
GO:0051224	negative regulation of protein transport	10/896	127/18722	0.0835623755246364	0.200003642477512	IL1B/LRRK2/CD36/UCP2/CSK/MIDN/SP100/CHP1/RAB11FIP1/PPP3CA	10
GO:0006446	regulation of translational initiation	7/896	79/18722	0.0836173357928845	0.200043129465866	TNF/EIF1/EIF4EBP1/PPP1R15A/PPP1R15B/EIF3K/DDX3X	7
GO:0006692	prostanoid metabolic process	5/896	49/18722	0.0838963011712945	0.200341901924657	IL1B/CD74/PTGS2/TBXAS1/TNFRSF1A	5
GO:0006693	prostaglandin metabolic process	5/896	49/18722	0.0838963011712945	0.200341901924657	IL1B/CD74/PTGS2/TBXAS1/TNFRSF1A	5
GO:1904752	regulation of vascular associated smooth muscle cell migration	5/896	49/18722	0.0838963011712945	0.200341901924657	MEF2C/IQGAP1/RHOA/PAK1/GNA13	5
GO:1990928	response to amino acid starvation	5/896	49/18722	0.0838963011712945	0.200341901924657	UCP2/EIF4EBP1/CDKN1A/MAPK1/ATF3	5
GO:0001893	maternal placenta development	4/896	35/18722	0.084475839621684	0.20052891002847	JUNB/PTGS2/CTSB/MAPK1	4
GO:0003298	physiological muscle hypertrophy	4/896	35/18722	0.084475839621684	0.20052891002847	RGS2/AKAP13/G6PD/PAK1	4
GO:0003301	physiological cardiac muscle hypertrophy	4/896	35/18722	0.084475839621684	0.20052891002847	RGS2/AKAP13/G6PD/PAK1	4
GO:0008608	attachment of spindle microtubules to kinetochore	4/896	35/18722	0.084475839621684	0.20052891002847	CDC42/RB1/HNRNPU/ZNF207	4
GO:0021955	central nervous system neuron axonogenesis	4/896	35/18722	0.084475839621684	0.20052891002847	NR4A2/NIN/PTEN/MYCBP2	4
GO:0032232	negative regulation of actin filament bundle assembly	4/896	35/18722	0.084475839621684	0.20052891002847	WAS/ARAP1/PAK2/PFN1	4
GO:0035633	maintenance of blood-brain barrier	4/896	35/18722	0.084475839621684	0.20052891002847	ACTB/PTGS2/PECAM1/MBP	4
GO:0043243	positive regulation of protein-containing complex disassembly	4/896	35/18722	0.084475839621684	0.20052891002847	PLEK/TNF/SETX/CALCOCO2	4
GO:0060236	regulation of mitotic spindle organization	4/896	35/18722	0.084475839621684	0.20052891002847	HSPA1A/HNRNPU/CHMP1B/NUP62	4
GO:0061049	cell growth involved in cardiac muscle cell development	4/896	35/18722	0.084475839621684	0.20052891002847	RGS2/AKAP13/G6PD/PAK1	4
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	4/896	35/18722	0.084475839621684	0.20052891002847	PTGS2/MAP3K3/HMOX1/CIB1	4
GO:1903514	release of sequestered calcium ion into cytosol by endoplasmic reticulum	4/896	35/18722	0.084475839621684	0.20052891002847	CCL3/SLC8A1/CALM2/PRKACA	4
GO:1905508	protein localization to microtubule organizing center	4/896	35/18722	0.084475839621684	0.20052891002847	SNX10/CEP350/NUP62/HOOK3	4
GO:0008593	regulation of Notch signaling pathway	8/896	95/18722	0.0848441552983198	0.201311337457373	NFKBIA/LFNG/BCL6/STAT3/TSPAN14/ADAM10/BMP2K/ZBTB7A	8
GO:0055002	striated muscle cell development	6/896	64/18722	0.0850248501033078	0.201585694326506	AKAP13/MEF2A/PRKAR1A/CFLAR/FLII/PLEC	6
GO:1901987	regulation of cell cycle phase transition	25/896	390/18722	0.085072486534487	0.201585694326506	AIF1/DUSP1/ZFP36L2/KLF4/PTPN6/BID/ZFP36L1/PSME2/PSME1/TAOK3/CDKN1A/KMT2E/PTEN/RB1/ATM/NABP1/FOXN3/TAOK1/WAC/LSM10/ADAM17/DDX3X/CTDSP1/ZNF207/DYNC1LI1	25
GO:0002053	positive regulation of mesenchymal cell proliferation	3/896	22/18722	0.0855799294506682	0.201585694326506	STAT1/TGFBR2/IRS2	3
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	3/896	22/18722	0.0855799294506682	0.201585694326506	SLC8A1/CALM2/PRKACA	3
GO:0032700	negative regulation of interleukin-17 production	3/896	22/18722	0.0855799294506682	0.201585694326506	NCKAP1L/TLR4/PRNP	3
GO:0035089	establishment of apical/basal cell polarity	3/896	22/18722	0.0855799294506682	0.201585694326506	MSN/RHOA/CDC42	3
GO:0035584	calcium-mediated signaling using intracellular calcium source	3/896	22/18722	0.0855799294506682	0.201585694326506	PTPRC/PRKACA/PRNP	3
GO:0036120	cellular response to platelet-derived growth factor stimulus	3/896	22/18722	0.0855799294506682	0.201585694326506	TLR4/FYN/CREB1	3
GO:0044346	fibroblast apoptotic process	3/896	22/18722	0.0855799294506682	0.201585694326506	STK17B/BID/BTG1	3
GO:0045624	positive regulation of T-helper cell differentiation	3/896	22/18722	0.0855799294506682	0.201585694326506	NFKBIZ/CD86/NLRP3	3
GO:0051412	response to corticosterone	3/896	22/18722	0.0855799294506682	0.201585694326506	FOS/FOSB/CDKN1A	3
GO:0060713	labyrinthine layer morphogenesis	3/896	22/18722	0.0855799294506682	0.201585694326506	SOCS3/ZFP36L1/GRB2	3
GO:0071359	cellular response to dsRNA	3/896	22/18722	0.0855799294506682	0.201585694326506	RALB/IFIH1/NFKB1	3
GO:0099563	modification of synaptic structure	3/896	22/18722	0.0855799294506682	0.201585694326506	RHOA/CDC42/PFN1	3
GO:0140467	integrated stress response signaling	3/896	22/18722	0.0855799294506682	0.201585694326506	PPP1R15A/PPP1R15B/PTPN2	3
GO:2000725	regulation of cardiac muscle cell differentiation	3/896	22/18722	0.0855799294506682	0.201585694326506	ARRB2/MEF2C/TGFB1	3
GO:0035265	organ growth	13/896	178/18722	0.0858560085418571	0.202144454697238	RGS2/DUSP6/PSAP/MEF2C/SERP1/AKAP13/STK4/G6PD/PAK1/PRKAR1A/PTEN/MAPK1/TGFBR2	13
GO:0044262	cellular carbohydrate metabolic process	19/896	283/18722	0.0868489131748231	0.204389682091518	PLEK/AOAH/PTAFR/PTK2B/FBP1/MIDN/CSGALNACT2/PDK4/PRKAG2/NAGK/STAT3/PTEN/PGD/PYGL/IRS2/PTPN2/PPIP5K2/EP300/RB1CC1	19
GO:0001570	vasculogenesis	7/896	80/18722	0.088063528923422	0.207154416069976	JUNB/TGFB1/ZFP36L1/RAP1A/RRAS/TGFBR2/QKI	7
GO:0001676	long-chain fatty acid metabolic process	9/896	112/18722	0.088367753804395	0.207682190481997	PTGS2/CYP1B1/GPX1/ALOX5/TBXAS1/ACSL1/ELOVL5/ACSL4/QKI	9
GO:0048640	negative regulation of developmental growth	9/896	112/18722	0.088367753804395	0.207682190481997	RGS2/PLAC8/ARHGAP4/STK4/G6PD/PAK1/CDKN1A/PTEN/TGFBR2	9
GO:0002639	positive regulation of immunoglobulin production	5/896	50/18722	0.0897426155879043	0.210532856866347	PTPRC/HLA-E/TGFB1/CD86/STAT6	5
GO:0070231	T cell apoptotic process	5/896	50/18722	0.0897426155879043	0.210532856866347	TSC22D3/LGALS9/GIMAP8/DOCK8/HIF1A	5
GO:1903747	regulation of establishment of protein localization to mitochondrion	5/896	50/18722	0.0897426155879043	0.210532856866347	LRRK2/RAC2/BNIP3L/UBE2D3/TOMM7	5
GO:1904738	vascular associated smooth muscle cell migration	5/896	50/18722	0.0897426155879043	0.210532856866347	MEF2C/IQGAP1/RHOA/PAK1/GNA13	5
GO:0038034	signal transduction in absence of ligand	6/896	65/18722	0.0900904835701325	0.211063335607324	IL1B/MCL1/BCL2A1/TNF/FYN/HSPA1A	6
GO:0043489	RNA stabilization	6/896	65/18722	0.0900904835701325	0.211063335607324	ZFP36/SLC11A1/PABPC1/MYD88/YBX1/HNRNPU	6
GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	6/896	65/18722	0.0900904835701325	0.211063335607324	IL1B/MCL1/BCL2A1/TNF/FYN/HSPA1A	6
GO:0007093	mitotic cell cycle checkpoint signaling	10/896	129/18722	0.0904759675340966	0.211871007269174	DUSP1/TAOK3/CDKN1A/ATM/NABP1/FOXN3/TAOK1/WAC/ZNF207/DYNC1LI1	10
GO:0002691	regulation of cellular extravasation	4/896	36/18722	0.0916176131251572	0.214062536327018	ITGA4/CCR2/BST1/PTAFR	4
GO:0045191	regulation of isotype switching	4/896	36/18722	0.0916176131251572	0.214062536327018	PTPRC/TGFB1/STAT6/BCL6	4
GO:0045746	negative regulation of Notch signaling pathway	4/896	36/18722	0.0916176131251572	0.214062536327018	NFKBIA/LFNG/BCL6/ZBTB7A	4
GO:0046466	membrane lipid catabolic process	4/896	36/18722	0.0916176131251572	0.214062536327018	CYP1B1/PPT1/ASAH1/NAGA	4
GO:0097009	energy homeostasis	4/896	36/18722	0.0916176131251572	0.214062536327018	CD36/METRNL/STAT3/PRCP	4
GO:0061025	membrane fusion	12/896	163/18722	0.0919155320857534	0.21456583589677	CORO1A/GCA/STX11/SAMD9/STX10/RAB8B/CHP1/PIP4K2A/GNAI3/STX7/STX12/BLOC1S6	12
GO:0071322	cellular response to carbohydrate stimulus	12/896	163/18722	0.0919155320857534	0.21456583589677	CYBA/LGALS1/CLEC7A/HLA-DRB1/UCP2/PRKCB/ZFP36L1/NADK/PRKACA/HIF1A/IRS2/PPP3CA	12
GO:0044344	cellular response to fibroblast growth factor stimulus	9/896	113/18722	0.092174522460038	0.215073885740089	ZFP36/ZFP36L2/CD44/CXCL8/NR4A1/SULF2/ZFP36L1/SETX/SHOC2	9
GO:0015918	sterol transport	10/896	130/18722	0.0940575593787467	0.215811386963968	TSPO/NFKBIA/CD36/NPC2/OSBPL8/RXRA/PIP4K2A/LAMTOR1/NFKB1/STX12	10
GO:0006002	fructose 6-phosphate metabolic process	2/896	11/18722	0.0945083156292462	0.215811386963968	FBP1/TALDO1	2
GO:0006971	hypotonic response	2/896	11/18722	0.0945083156292462	0.215811386963968	TSPO/CAB39	2
GO:0008611	ether lipid biosynthetic process	2/896	11/18722	0.0945083156292462	0.215811386963968	LPCAT2/FAR1	2
GO:0009155	purine deoxyribonucleotide catabolic process	2/896	11/18722	0.0945083156292462	0.215811386963968	SAMHD1/NUDT16	2
GO:0010269	response to selenium ion	2/896	11/18722	0.0945083156292462	0.215811386963968	SOD2/GPX1	2
GO:0019048	modulation by virus of host process	2/896	11/18722	0.0945083156292462	0.215811386963968	CD4/RXRA	2
GO:0030656	regulation of vitamin metabolic process	2/896	11/18722	0.0945083156292462	0.215811386963968	TNF/NFKB1	2
GO:0032957	inositol trisphosphate metabolic process	2/896	11/18722	0.0945083156292462	0.215811386963968	PTAFR/PTK2B	2
GO:0033483	gas homeostasis	2/896	11/18722	0.0945083156292462	0.215811386963968	SOD2/HIF1A	2
GO:0033625	positive regulation of integrin activation	2/896	11/18722	0.0945083156292462	0.215811386963968	PLEK/RAP1B	2
GO:0033632	regulation of cell-cell adhesion mediated by integrin	2/896	11/18722	0.0945083156292462	0.215811386963968	FERMT3/WNK1	2
GO:0034454	microtubule anchoring at centrosome	2/896	11/18722	0.0945083156292462	0.215811386963968	NIN/HOOK3	2
GO:0039530	MDA-5 signaling pathway	2/896	11/18722	0.0945083156292462	0.215811386963968	IRF7/IFIH1	2
GO:0042416	dopamine biosynthetic process	2/896	11/18722	0.0945083156292462	0.215811386963968	NR4A2/GCH1	2
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	2/896	11/18722	0.0945083156292462	0.215811386963968	HIF1A/HMOX1	2
GO:0045793	positive regulation of cell size	2/896	11/18722	0.0945083156292462	0.215811386963968	TMEM123/RB1CC1	2
GO:0046504	glycerol ether biosynthetic process	2/896	11/18722	0.0945083156292462	0.215811386963968	LPCAT2/FAR1	2
GO:0046929	negative regulation of neurotransmitter secretion	2/896	11/18722	0.0945083156292462	0.215811386963968	RAP1A/RAP1B	2
GO:0048680	positive regulation of axon regeneration	2/896	11/18722	0.0945083156292462	0.215811386963968	FLNA/GRN	2
GO:0060312	regulation of blood vessel remodeling	2/896	11/18722	0.0945083156292462	0.215811386963968	CST3/TGFB1	2
GO:0060746	parental behavior	2/896	11/18722	0.0945083156292462	0.215811386963968	PTEN/MBD2	2
GO:0070417	cellular response to cold	2/896	11/18722	0.0945083156292462	0.215811386963968	NFKBIA/PRKACA	2
GO:0070944	neutrophil-mediated killing of bacterium	2/896	11/18722	0.0945083156292462	0.215811386963968	TREM1/MYD88	2
GO:0071044	histone mRNA catabolic process	2/896	11/18722	0.0945083156292462	0.215811386963968	ATM/XRN1	2
GO:0071609	chemokine (C-C motif) ligand 5 production	2/896	11/18722	0.0945083156292462	0.215811386963968	SIRPA/DDX3X	2
GO:0071649	regulation of chemokine (C-C motif) ligand 5 production	2/896	11/18722	0.0945083156292462	0.215811386963968	SIRPA/DDX3X	2
GO:0071888	macrophage apoptotic process	2/896	11/18722	0.0945083156292462	0.215811386963968	MEF2C/IRF7	2
GO:0075733	intracellular transport of virus	2/896	11/18722	0.0945083156292462	0.215811386963968	BST2/DYNLT1	2
GO:0090084	negative regulation of inclusion body assembly	2/896	11/18722	0.0945083156292462	0.215811386963968	SORL1/HSPA1A	2
GO:0090394	negative regulation of excitatory postsynaptic potential	2/896	11/18722	0.0945083156292462	0.215811386963968	LRRK2/PTEN	2
GO:0090649	response to oxygen-glucose deprivation	2/896	11/18722	0.0945083156292462	0.215811386963968	NAMPT/BNIP2	2
GO:0097384	cellular lipid biosynthetic process	2/896	11/18722	0.0945083156292462	0.215811386963968	LPCAT2/FAR1	2
GO:0097494	regulation of vesicle size	2/896	11/18722	0.0945083156292462	0.215811386963968	RIN3/PICALM	2
GO:0098883	synapse pruning	2/896	11/18722	0.0945083156292462	0.215811386963968	CX3CR1/ITGAM	2
GO:0106049	regulation of cellular response to osmotic stress	2/896	11/18722	0.0945083156292462	0.215811386963968	PTGS2/MICU1	2
GO:1900222	negative regulation of amyloid-beta clearance	2/896	11/18722	0.0945083156292462	0.215811386963968	TNF/IFNGR1	2
GO:1900426	positive regulation of defense response to bacterium	2/896	11/18722	0.0945083156292462	0.215811386963968	CYBA/GRN	2
GO:1902337	regulation of apoptotic process involved in morphogenesis	2/896	11/18722	0.0945083156292462	0.215811386963968	TNFRSF1B/TNFRSF1A	2
GO:1904464	regulation of matrix metallopeptidase secretion	2/896	11/18722	0.0945083156292462	0.215811386963968	TLR2/TLR4	2
GO:1905050	positive regulation of metallopeptidase activity	2/896	11/18722	0.0945083156292462	0.215811386963968	MBP/STAT3	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	2/896	11/18722	0.0945083156292462	0.215811386963968	CEBPB/ATF3	2
GO:1990773	matrix metallopeptidase secretion	2/896	11/18722	0.0945083156292462	0.215811386963968	TLR2/TLR4	2
GO:2000392	regulation of lamellipodium morphogenesis	2/896	11/18722	0.0945083156292462	0.215811386963968	CD44/CORO1C	2
GO:2000480	negative regulation of cAMP-dependent protein kinase activity	2/896	11/18722	0.0945083156292462	0.215811386963968	PRKAG2/PRKAR1A	2
GO:2000644	regulation of receptor catabolic process	2/896	11/18722	0.0945083156292462	0.215811386963968	LAPTM5/DTX3L	2
GO:2000786	positive regulation of autophagosome assembly	2/896	11/18722	0.0945083156292462	0.215811386963968	RALB/PIP4K2A	2
GO:0001889	liver development	11/896	147/18722	0.0949439101290787	0.215811386963968	TNFAIP3/CEBPB/UCP2/NOTCH2/SULF2/RAP1A/CFLAR/HMOX1/TAF10/RB1CC1/SP3	11
GO:0009162	deoxyribonucleoside monophosphate metabolic process	3/896	23/18722	0.0950706150874888	0.215811386963968	TYMP/DPYD/UPP1	3
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	3/896	23/18722	0.0950706150874888	0.215811386963968	CARD16/CARD8/PTPN2	3
GO:0016578	histone deubiquitination	3/896	23/18722	0.0950706150874888	0.215811386963968	USP15/USP3/TAF10	3
GO:0019430	removal of superoxide radicals	3/896	23/18722	0.0950706150874888	0.215811386963968	SOD2/CD36/GCH1	3
GO:0036119	response to platelet-derived growth factor	3/896	23/18722	0.0950706150874888	0.215811386963968	TLR4/FYN/CREB1	3
GO:0042026	protein refolding	3/896	23/18722	0.0950706150874888	0.215811386963968	B2M/HSPA1A/FKBP1A	3
GO:0045980	negative regulation of nucleotide metabolic process	3/896	23/18722	0.0950706150874888	0.215811386963968	CDA/FBP1/STAT3	3
GO:0051882	mitochondrial depolarization	3/896	23/18722	0.0950706150874888	0.215811386963968	TSPO/LRRK2/CASP1	3
GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	3/896	23/18722	0.0950706150874888	0.215811386963968	TYROBP/CD53/CAPN2	3
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	3/896	23/18722	0.0950706150874888	0.215811386963968	RGS2/G6PD/PAK1	3
GO:0072677	eosinophil migration	3/896	23/18722	0.0950706150874888	0.215811386963968	CCL3/CD300A/CCL4	3
GO:0090335	regulation of brown fat cell differentiation	3/896	23/18722	0.0950706150874888	0.215811386963968	PTGS2/METRNL/HNRNPU	3
GO:1902410	mitotic cytokinetic process	3/896	23/18722	0.0950706150874888	0.215811386963968	RHOA/CHMP1B/NUP62	3
GO:2000737	negative regulation of stem cell differentiation	3/896	23/18722	0.0950706150874888	0.215811386963968	ZFP36L2/STAT3/HNRNPU	3
GO:2000058	regulation of ubiquitin-dependent protein catabolic process	12/896	164/18722	0.0951047296522621	0.215811386963968	LAPTM5/LRRK2/PTK2B/HSPA1A/AGTPBP1/TRIB1/GABARAP/SDCBP/PTEN/PIAS1/WAC/HERPUD1	12
GO:0003015	heart process	17/896	251/18722	0.0951771820012635	0.215881606449442	RGS2/FLNA/GNAI2/CELF2/GPX1/JAK2/HBEGF/SLC8A1/KCNE3/CXCR4/FYN/GCH1/AKAP13/CALM2/MEF2A/CDC42/PRKACA	17
GO:1905953	negative regulation of lipid localization	6/896	66/18722	0.0953164685778416	0.216103292534156	NFKBIA/TNF/OSBPL8/IRS2/PTPN2/NFKB1	6
GO:0006636	unsaturated fatty acid biosynthetic process	5/896	51/18722	0.0957940688591206	0.216713767784378	IL1B/CD74/PTGS2/TBXAS1/ELOVL5	5
GO:0010656	negative regulation of muscle cell apoptotic process	5/896	51/18722	0.0957940688591206	0.216713767784378	ARRB2/JAK2/PTK2B/CFLAR/HMOX1	5
GO:0032873	negative regulation of stress-activated MAPK cascade	5/896	51/18722	0.0957940688591206	0.216713767784378	DUSP1/TAOK3/SIRPA/HIPK3/CYLD	5
GO:0045661	regulation of myoblast differentiation	5/896	51/18722	0.0957940688591206	0.216713767784378	MEF2C/TGFB1/TNF/ZFP36L1/BTG1	5
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	5/896	51/18722	0.0957940688591206	0.216713767784378	DUSP1/TAOK3/SIRPA/HIPK3/CYLD	5
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	9/896	114/18722	0.0960760558271645	0.217257202763949	ZEB2/JAK2/TGFB1/NOTCH2/C20orf27/SDCBP/ADAM17/CREBBP/EP300	9
GO:0048588	developmental cell growth	16/896	234/18722	0.0968979472157433	0.219020523020026	RGS2/ITGA4/IQGAP1/CXCR4/ARHGAP4/DPYSL2/AKAP13/G6PD/NIN/C9orf72/SHTN1/PAK1/TWF2/ITSN2/DBNL/TGFBR2	16
GO:0043473	pigmentation	8/896	98/18722	0.0973313126399699	0.219753327638875	ZEB2/LYST/MEF2C/RAB32/RAB27A/BLOC1S1/ATP6AP2/BLOC1S6	8
GO:0046364	monosaccharide biosynthetic process	7/896	82/18722	0.0973489073024358	0.219753327638875	FBP1/G6PD/PGD/PGK1/ATF3/PTPN2/EP300	7
GO:0072527	pyrimidine-containing compound metabolic process	7/896	82/18722	0.0973489073024358	0.219753327638875	TYMP/APOBEC3A/DPYD/CDA/UPP1/MAPK1/TET2	7
GO:1904950	negative regulation of establishment of protein localization	10/896	131/18722	0.097722174958619	0.220500230785153	IL1B/LRRK2/CD36/UCP2/CSK/MIDN/SP100/CHP1/RAB11FIP1/PPP3CA	10
GO:0051260	protein homooligomerization	13/896	182/18722	0.0978087104739411	0.220599784551157	SAMHD1/PYCARD/SOD2/B2M/KCTD12/RNF213/VASP/GBP5/SHKBP1/ALOX5AP/MICU1/PRNP/NINJ1	13
GO:0001990	regulation of systemic arterial blood pressure by hormone	4/896	37/18722	0.0990367242372665	0.222693472874199	CYBA/CTSZ/RHOA/ATP6AP2	4
GO:0016202	regulation of striated muscle tissue development	4/896	37/18722	0.0990367242372665	0.222693472874199	MEF2C/TGFB1/MTPN/CREB1	4
GO:0031646	positive regulation of nervous system process	4/896	37/18722	0.0990367242372665	0.222693472874199	TNFRSF1B/ITGAX/PTAFR/DICER1	4
GO:0033363	secretory granule organization	4/896	37/18722	0.0990367242372665	0.222693472874199	SRGN/LYST/BLOC1S1/CREB1	4
GO:0042401	cellular biogenic amine biosynthetic process	4/896	37/18722	0.0990367242372665	0.222693472874199	NR4A2/OAZ1/SAT1/GCH1	4
GO:0060416	response to growth hormone	4/896	37/18722	0.0990367242372665	0.222693472874199	LYN/JAK2/STAT6/STAT3	4
GO:0071985	multivesicular body sorting pathway	4/896	37/18722	0.0990367242372665	0.222693472874199	LYST/RAB27A/TMEM50A/CHMP1B	4
GO:0061013	regulation of mRNA catabolic process	12/896	166/18722	0.10168240598153	0.228513693684167	ZFP36/VIM/ZFP36L2/SLC11A1/BTG2/PABPC1/MYD88/ZFP36L1/ROCK1/YBX1/HNRNPU/CELF1	12
GO:0006165	nucleoside diphosphate phosphorylation	8/896	99/18722	0.101712978442385	0.228513693684167	FBP1/PRKAG2/STAT3/HIF1A/PGK1/ZBTB7A/ADPGK/EP300	8
GO:0010718	positive regulation of epithelial to mesenchymal transition	5/896	52/18722	0.102047180462704	0.229066631673078	IL1B/GLIPR2/TGFB1/SDCBP/TGFBR2	5
GO:0051496	positive regulation of stress fiber assembly	5/896	52/18722	0.102047180462704	0.229066631673078	CCDC88A/RHOA/GPR65/PAK1/CDC42	5
GO:1901292	nucleoside phosphate catabolic process	7/896	83/18722	0.102186227708395	0.229279797373323	TYMP/SAMHD1/DPYD/UPP1/ENTPD1/NUDT16/NUDT3	7
GO:0000209	protein polyubiquitination	16/896	236/18722	0.102399197558786	0.229658571152759	TNFAIP3/UBE2L6/TRIM22/UBE2D1/TRIM38/RNF166/DTX3L/GABARAP/UBE2D3/UBE2R2/LNPEP/NMI/DDX3X/SPOP/TRIP12/BIRC2	16
GO:0009165	nucleotide biosynthetic process	17/896	254/18722	0.103092754867963	0.231114404339773	TMSB4X/NAMPT/PPT1/TGFB1/UPP1/PARP9/KYNU/ACSL1/PDK4/NADK/PRKAG2/ELOVL5/ATP6V1A/STAT3/ADCY7/MAPK1/ACSL4	17
GO:0055001	muscle cell development	13/896	184/18722	0.104147093718433	0.233209975365391	RGS2/GPX1/SLC8A1/AKAP13/MEF2A/G6PD/PAK1/PRKAR1A/CFLAR/FLII/HNRNPU/PPP3CA/PLEC	13
GO:0033559	unsaturated fatty acid metabolic process	9/896	116/18722	0.10416204052563	0.233209975365391	IL1B/CD74/PTGS2/CYP1B1/GPX1/ALOX5/TBXAS1/ELOVL5/TNFRSF1A	9
GO:0035967	cellular response to topologically incorrect protein	9/896	116/18722	0.10416204052563	0.233209975365391	SERP1/HSPA1A/PPP1R15A/PPP1R15B/ATF3/PTPN2/TMBIM6/EP300/HERPUD1	9
GO:0002922	positive regulation of humoral immune response	3/896	24/18722	0.104968767049606	0.233808375770878	IL1B/PTPRC/TNF	3
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	3/896	24/18722	0.104968767049606	0.233808375770878	TYMP/DPYD/UPP1	3
GO:0010155	regulation of proton transport	3/896	24/18722	0.104968767049606	0.233808375770878	TMSB4X/TCIRG1/CHP1	3
GO:0010226	response to lithium ion	3/896	24/18722	0.104968767049606	0.233808375770878	PTGS2/PTK2B/ADCY7	3
GO:0036010	protein localization to endosome	3/896	24/18722	0.104968767049606	0.233808375770878	MSN/SORL1/DTX3L	3
GO:0050687	negative regulation of defense response to virus	3/896	24/18722	0.104968767049606	0.233808375770878	FGL2/PCBP2/SEC14L1	3
GO:0051647	nucleus localization	3/896	24/18722	0.104968767049606	0.233808375770878	CDC42/SUN2/HOOK3	3
GO:0060561	apoptotic process involved in morphogenesis	3/896	24/18722	0.104968767049606	0.233808375770878	TNFRSF1B/SPI1/TNFRSF1A	3
GO:0061162	establishment of monopolar cell polarity	3/896	24/18722	0.104968767049606	0.233808375770878	MSN/RHOA/CDC42	3
GO:0071294	cellular response to zinc ion	3/896	24/18722	0.104968767049606	0.233808375770878	TSPO/HVCN1/CREB1	3
GO:0072010	glomerular epithelium development	3/896	24/18722	0.104968767049606	0.233808375770878	PECAM1/IQGAP1/NOTCH2	3
GO:2000209	regulation of anoikis	3/896	24/18722	0.104968767049606	0.233808375770878	MCL1/PDK4/ITGA5	3
GO:1903034	regulation of response to wounding	12/896	167/18722	0.105070699176183	0.233935233910671	CLEC7A/FLNA/KLF4/CD36/TNFAIP3/GRN/HBEGF/CXCR4/TNF/ALOX5/SH2B3/PTEN	12
GO:0010565	regulation of cellular ketone metabolic process	10/896	133/18722	0.105299558001417	0.234244226332493	IL1B/CD74/EGR1/PTGS2/SLC7A7/LPGAT1/PDK4/PRKAG2/ELOVL5/IRS2	10
GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process	10/896	133/18722	0.105299558001417	0.234244226332493	LAPTM5/LRRK2/PTK2B/HSPA1A/AGTPBP1/TRIB1/GABARAP/PTEN/PIAS1/HERPUD1	10
GO:0016051	carbohydrate biosynthetic process	14/896	202/18722	0.105956104495308	0.235603975835868	PLEK/TGFB1/PTAFR/PTK2B/FBP1/CSGALNACT2/G6PD/PGD/PGK1/ATF3/IRS2/PTPN2/EP300/NFKB1	14
GO:0044728	DNA methylation or demethylation	8/896	100/18722	0.106203204096951	0.235937749550518	FOS/APOBEC3A/SPI1/KDM1B/KMT2E/TET2/MBD2/KMT2A	8
GO:0031640	killing of cells of other organism	6/896	68/18722	0.106242301374219	0.235937749550518	LYZ/S100A12/CLEC7A/SYK/TREM1/MYD88	6
GO:0051926	negative regulation of calcium ion transport	6/896	68/18722	0.106242301374219	0.235937749550518	PTGS2/LILRB2/LILRB1/CD33/CALM2/TMBIM6	6
GO:0007094	mitotic spindle assembly checkpoint signaling	4/896	38/18722	0.10672503198437	0.236002079655913	DUSP1/ATM/ZNF207/DYNC1LI1	4
GO:0009309	amine biosynthetic process	4/896	38/18722	0.10672503198437	0.236002079655913	NR4A2/OAZ1/SAT1/GCH1	4
GO:0010613	positive regulation of cardiac muscle hypertrophy	4/896	38/18722	0.10672503198437	0.236002079655913	MEF2A/MTPN/ROCK1/PPP3CA	4
GO:0046329	negative regulation of JNK cascade	4/896	38/18722	0.10672503198437	0.236002079655913	TAOK3/SIRPA/HIPK3/CYLD	4
GO:0071173	spindle assembly checkpoint signaling	4/896	38/18722	0.10672503198437	0.236002079655913	DUSP1/ATM/ZNF207/DYNC1LI1	4
GO:0071174	mitotic spindle checkpoint signaling	4/896	38/18722	0.10672503198437	0.236002079655913	DUSP1/ATM/ZNF207/DYNC1LI1	4
GO:0072524	pyridine-containing compound metabolic process	4/896	38/18722	0.10672503198437	0.236002079655913	NAMPT/PARP9/KYNU/NADK	4
GO:0072538	T-helper 17 type immune response	4/896	38/18722	0.10672503198437	0.236002079655913	NFKBIZ/CLEC7A/IL6R/STAT3	4
GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	4/896	38/18722	0.10672503198437	0.236002079655913	BID/HSPA1A/CHCHD10/BNIP3L	4
GO:2000279	negative regulation of DNA biosynthetic process	4/896	38/18722	0.10672503198437	0.236002079655913	DUSP1/CDKN1A/HNRNPU/XRN1	4
GO:0061157	mRNA destabilization	7/896	84/18722	0.10715178469795	0.236744448689055	ZFP36/ZFP36L2/BTG2/PABPC1/ZFP36L1/ROCK1/CELF1	7
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	7/896	84/18722	0.10715178469795	0.236744448689055	KLF4/CDKN1A/PTEN/RB1/ATM/WAC/CTDSP1	7
GO:0014902	myotube differentiation	9/896	117/18722	0.108345587864512	0.237742858882786	PLEKHO1/CD53/MEF2C/GPX1/CAPN2/CFLAR/MYH9/PPP3CA/PLEC	9
GO:0030301	cholesterol transport	9/896	117/18722	0.108345587864512	0.237742858882786	TSPO/NFKBIA/CD36/NPC2/RXRA/PIP4K2A/LAMTOR1/NFKB1/STX12	9
GO:1903202	negative regulation of oxidative stress-induced cell death	5/896	53/18722	0.108498095145802	0.237742858882786	SOD2/LRRK2/GPX1/FYN/HIF1A	5
GO:2000772	regulation of cellular senescence	5/896	53/18722	0.108498095145802	0.237742858882786	NAMPT/B2M/BCL6/MAP3K3/YBX1	5
GO:0099173	postsynapse organization	12/896	168/18722	0.108525102353891	0.237742858882786	SRGN/LRRK2/ACTB/LILRB2/ACTR2/FYN/CFL1/CDC42/PTEN/ADAM10/DBNL/PRNP	12
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	17/896	256/18722	0.108590159621897	0.237742858882786	ZEB2/JAK2/TGFB1/NOTCH2/SORL1/C20orf27/UBE2D1/HSPA1A/FKBP1A/SKIL/SDCBP/UBE2D3/ZBTB7A/ADAM17/CREBBP/EP300/FAM89B	17
GO:1901293	nucleoside phosphate biosynthetic process	17/896	256/18722	0.108590159621897	0.237742858882786	TMSB4X/NAMPT/PPT1/TGFB1/UPP1/PARP9/KYNU/ACSL1/PDK4/NADK/PRKAG2/ELOVL5/ATP6V1A/STAT3/ADCY7/MAPK1/ACSL4	17
GO:0042552	myelination	10/896	134/18722	0.109211700788824	0.237742858882786	TYMP/TNFRSF1B/TLR2/CXCR4/ITGAX/MBP/PTEN/DICER1/QKI/PLEC	10
GO:0001821	histamine secretion	2/896	12/18722	0.109934930900423	0.237742858882786	LYN/BTK	2
GO:0006068	ethanol catabolic process	2/896	12/18722	0.109934930900423	0.237742858882786	ALDH2/SULT1A1	2
GO:0006216	cytidine catabolic process	2/896	12/18722	0.109934930900423	0.237742858882786	APOBEC3A/CDA	2
GO:0009972	cytidine deamination	2/896	12/18722	0.109934930900423	0.237742858882786	APOBEC3A/CDA	2
GO:0014831	gastro-intestinal system smooth muscle contraction	2/896	12/18722	0.109934930900423	0.237742858882786	SULF2/PTAFR	2
GO:0032736	positive regulation of interleukin-13 production	2/896	12/18722	0.109934930900423	0.237742858882786	HLA-E/LGALS9	2
GO:0032908	regulation of transforming growth factor beta1 production	2/896	12/18722	0.109934930900423	0.237742858882786	TYROBP/ATP6AP2	2
GO:0033523	histone H2B ubiquitination	2/896	12/18722	0.109934930900423	0.237742858882786	DTX3L/WAC	2
GO:0033629	negative regulation of cell adhesion mediated by integrin	2/896	12/18722	0.109934930900423	0.237742858882786	CYP1B1/WNK1	2
GO:0034086	maintenance of sister chromatid cohesion	2/896	12/18722	0.109934930900423	0.237742858882786	RB1/NIPBL	2
GO:0034088	maintenance of mitotic sister chromatid cohesion	2/896	12/18722	0.109934930900423	0.237742858882786	RB1/NIPBL	2
GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	2/896	12/18722	0.109934930900423	0.237742858882786	IFI35/NINJ1	2
GO:0035739	CD4-positive, alpha-beta T cell proliferation	2/896	12/18722	0.109934930900423	0.237742858882786	LGALS9/TGFBR2	2
GO:0038180	nerve growth factor signaling pathway	2/896	12/18722	0.109934930900423	0.237742858882786	CORO1A/RAP1A	2
GO:0042117	monocyte activation	2/896	12/18722	0.109934930900423	0.237742858882786	CD33/ADAM10	2
GO:0042762	regulation of sulfur metabolic process	2/896	12/18722	0.109934930900423	0.237742858882786	PDK4/SP1	2
GO:0043129	surfactant homeostasis	2/896	12/18722	0.109934930900423	0.237742858882786	CTSH/OAS1	2
GO:0043476	pigment accumulation	2/896	12/18722	0.109934930900423	0.237742858882786	RAB32/BLOC1S6	2
GO:0043482	cellular pigment accumulation	2/896	12/18722	0.109934930900423	0.237742858882786	RAB32/BLOC1S6	2
GO:0046087	cytidine metabolic process	2/896	12/18722	0.109934930900423	0.237742858882786	APOBEC3A/CDA	2
GO:0048548	regulation of pinocytosis	2/896	12/18722	0.109934930900423	0.237742858882786	PPT1/CDC42	2
GO:0051639	actin filament network formation	2/896	12/18722	0.109934930900423	0.237742858882786	LCP1/ARPC5	2
GO:0060009	Sertoli cell development	2/896	12/18722	0.109934930900423	0.237742858882786	FLNA/ARID4A	2
GO:0060019	radial glial cell differentiation	2/896	12/18722	0.109934930900423	0.237742858882786	RHOA/STAT3	2
GO:0061517	macrophage proliferation	2/896	12/18722	0.109934930900423	0.237742858882786	CSF1R/MAPK1	2
GO:0070572	positive regulation of neuron projection regeneration	2/896	12/18722	0.109934930900423	0.237742858882786	FLNA/GRN	2
GO:0070943	neutrophil-mediated killing of symbiont cell	2/896	12/18722	0.109934930900423	0.237742858882786	TREM1/MYD88	2
GO:0071107	response to parathyroid hormone	2/896	12/18722	0.109934930900423	0.237742858882786	MEF2C/PRKACA	2
GO:0071472	cellular response to salt stress	2/896	12/18722	0.109934930900423	0.237742858882786	ZFP36L1/MICU1	2
GO:0071635	negative regulation of transforming growth factor beta production	2/896	12/18722	0.109934930900423	0.237742858882786	TYROBP/LILRB1	2
GO:0072015	glomerular visceral epithelial cell development	2/896	12/18722	0.109934930900423	0.237742858882786	IQGAP1/NOTCH2	2
GO:0072683	T cell extravasation	2/896	12/18722	0.109934930900423	0.237742858882786	ITGAL/CCR2	2
GO:0098974	postsynaptic actin cytoskeleton organization	2/896	12/18722	0.109934930900423	0.237742858882786	ACTB/DBNL	2
GO:0140289	protein mono-ADP-ribosylation	2/896	12/18722	0.109934930900423	0.237742858882786	PARP9/PARP14	2
GO:0150065	regulation of deacetylase activity	2/896	12/18722	0.109934930900423	0.237742858882786	LRRK2/KDM5A	2
GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	2/896	12/18722	0.109934930900423	0.237742858882786	PLXNC1/PLXNB2	2
GO:1902950	regulation of dendritic spine maintenance	2/896	12/18722	0.109934930900423	0.237742858882786	FYN/PRNP	2
GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA	2/896	12/18722	0.109934930900423	0.237742858882786	TGFB1/DDX5	2
GO:1904748	regulation of apoptotic process involved in development	2/896	12/18722	0.109934930900423	0.237742858882786	TNFRSF1B/TNFRSF1A	2
GO:1905205	positive regulation of connective tissue replacement	2/896	12/18722	0.109934930900423	0.237742858882786	ROCK1/PPP3CA	2
GO:2000508	regulation of dendritic cell chemotaxis	2/896	12/18722	0.109934930900423	0.237742858882786	SPI1/LGALS9	2
GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation	2/896	12/18722	0.109934930900423	0.237742858882786	LGALS9/TGFBR2	2
GO:2001214	positive regulation of vasculogenesis	2/896	12/18722	0.109934930900423	0.237742858882786	RAP1A/RRAS	2
GO:0031345	negative regulation of cell projection organization	13/896	186/18722	0.110726191114989	0.239354497086058	VIM/LGALS1/B2M/LRRK2/FLNA/CTSZ/RHOA/FYN/ARHGAP4/PTEN/PPP3CA/PRNP/CIB1	13
GO:0046939	nucleotide phosphorylation	8/896	101/18722	0.110801168451638	0.239417065690473	FBP1/PRKAG2/STAT3/HIF1A/PGK1/ZBTB7A/ADPGK/EP300	8
GO:0021543	pallium development	12/896	169/18722	0.112045418366309	0.242005075134207	BCL2A1/FLNA/BTG2/RHOA/PHACTR1/KDM6B/PTEN/HIF1A/SUN2/MBOAT7/XRN2/CELF1	12
GO:0032092	positive regulation of protein binding	7/896	85/18722	0.112244240120314	0.242233316541807	B2M/LRRK2/FKBP1A/RALB/STK4/DTX3L/EP300	7
GO:0072384	organelle transport along microtubule	7/896	85/18722	0.112244240120314	0.242233316541807	BLOC1S1/AGTPBP1/CDC42/HIF1A/SUN2/BICD2/BLOC1S6	7
GO:0007613	memory	9/896	118/18722	0.112622093753372	0.242947950896429	PTGS2/CEBPB/CX3CR1/SGK1/PTEN/PJA2/NQO2/PRNP/CREB1	9
GO:0098754	detoxification	11/896	152/18722	0.112929558216429	0.243510212389572	S100A9/SOD2/CD36/PTGS2/GPX1/MGST1/ALDH1A1/GCH1/GLRX/ALOX5AP/GSTK1	11
GO:0140694	non-membrane-bounded organelle assembly	23/896	367/18722	0.113983759822878	0.245563582494343	LCP1/MSN/FLNA/HCK/TNF/RHOA/AKAP13/HSPA1A/MEF2A/CCDC69/C9orf72/PRKAR1A/CFLAR/BIN2/DBNL/FLII/STAG2/HNRNPU/DDX3X/PLEC/CHMP1B/NUP62/ZNF207	23
GO:0042593	glucose homeostasis	17/896	258/18722	0.114263679503663	0.245563582494343	CYBA/LGALS1/HLA-DRB1/UCP2/OAS1/ALOX5/CYB5R4/PDK4/NADK/PRKACA/STAT3/HIF1A/PYGL/PRCP/IRS2/PPP3CA/PTPN2	17
GO:0014742	positive regulation of muscle hypertrophy	4/896	39/18722	0.114673825626884	0.245563582494343	MEF2A/MTPN/ROCK1/PPP3CA	4
GO:0031577	spindle checkpoint signaling	4/896	39/18722	0.114673825626884	0.245563582494343	DUSP1/ATM/ZNF207/DYNC1LI1	4
GO:0042417	dopamine metabolic process	4/896	39/18722	0.114673825626884	0.245563582494343	ITGB2/NR4A2/ITGAM/GCH1	4
GO:0043267	negative regulation of potassium ion transport	4/896	39/18722	0.114673825626884	0.245563582494343	KCNE3/PTK2B/PTEN/CAB39	4
GO:0051154	negative regulation of striated muscle cell differentiation	4/896	39/18722	0.114673825626884	0.245563582494343	RGS2/G6PD/PAK1/YBX1	4
GO:0090224	regulation of spindle organization	4/896	39/18722	0.114673825626884	0.245563582494343	HSPA1A/HNRNPU/CHMP1B/NUP62	4
GO:1901861	regulation of muscle tissue development	4/896	39/18722	0.114673825626884	0.245563582494343	MEF2C/TGFB1/MTPN/CREB1	4
GO:2000785	regulation of autophagosome assembly	4/896	39/18722	0.114673825626884	0.245563582494343	LRRK2/RALB/C9orf72/PIP4K2A	4
GO:0010447	response to acidic pH	3/896	25/18722	0.115251048811515	0.245563582494343	CTSS/GPR65/CHP1	3
GO:0016540	protein autoprocessing	3/896	25/18722	0.115251048811515	0.245563582494343	CASP1/CAPN2/FAM111A	3
GO:0032469	endoplasmic reticulum calcium ion homeostasis	3/896	25/18722	0.115251048811515	0.245563582494343	TMBIM6/GRINA/HERPUD1	3
GO:0050995	negative regulation of lipid catabolic process	3/896	25/18722	0.115251048811515	0.245563582494343	IL1B/SORL1/TNF	3
GO:0060074	synapse maturation	3/896	25/18722	0.115251048811515	0.245563582494343	CX3CR1/PTEN/PFN1	3
GO:0061339	establishment or maintenance of monopolar cell polarity	3/896	25/18722	0.115251048811515	0.245563582494343	MSN/RHOA/CDC42	3
GO:0062149	detection of stimulus involved in sensory perception of pain	3/896	25/18722	0.115251048811515	0.245563582494343	ARRB2/CXCR4/FYN	3
GO:0071450	cellular response to oxygen radical	3/896	25/18722	0.115251048811515	0.245563582494343	SOD2/CD36/GCH1	3
GO:0071451	cellular response to superoxide	3/896	25/18722	0.115251048811515	0.245563582494343	SOD2/CD36/GCH1	3
GO:0086064	cell communication by electrical coupling involved in cardiac conduction	3/896	25/18722	0.115251048811515	0.245563582494343	SLC8A1/CALM2/PRKACA	3
GO:0090169	regulation of spindle assembly	3/896	25/18722	0.115251048811515	0.245563582494343	HSPA1A/HNRNPU/CHMP1B	3
GO:0090312	positive regulation of protein deacetylation	3/896	25/18722	0.115251048811515	0.245563582494343	LRRK2/BCL6/NIPBL	3
GO:0090382	phagosome maturation	3/896	25/18722	0.115251048811515	0.245563582494343	CORO1A/RAB32/TCIRG1	3
GO:0098703	calcium ion import across plasma membrane	3/896	25/18722	0.115251048811515	0.245563582494343	SLC8A1/FYN/PRNP	3
GO:0140448	signaling receptor ligand precursor processing	3/896	25/18722	0.115251048811515	0.245563582494343	CASP1/CTSZ/ATP6AP2	3
GO:1901798	positive regulation of signal transduction by p53 class mediator	3/896	25/18722	0.115251048811515	0.245563582494343	DDX5/ZNF385A/ATM	3
GO:1903055	positive regulation of extracellular matrix organization	3/896	25/18722	0.115251048811515	0.245563582494343	TGFB1/CFLAR/RB1	3
GO:1903959	regulation of anion transmembrane transport	3/896	25/18722	0.115251048811515	0.245563582494343	RGS2/PTAFR/PRNP	3
GO:1904753	negative regulation of vascular associated smooth muscle cell migration	3/896	25/18722	0.115251048811515	0.245563582494343	MEF2C/RHOA/GNA13	3
GO:0046034	ATP metabolic process	18/896	277/18722	0.117082740509778	0.249364182387942	TSPO/TMSB4X/TGFB1/BID/RHOA/FBP1/HSPA1A/NADK/ATP6V1B2/PRKAG2/CHCHD10/ATP6V1A/STAT3/HIF1A/PGK1/ZBTB7A/ADPGK/EP300	18
GO:0033500	carbohydrate homeostasis	17/896	259/18722	0.117166347564942	0.249377610158743	CYBA/LGALS1/HLA-DRB1/UCP2/OAS1/ALOX5/CYB5R4/PDK4/NADK/PRKACA/STAT3/HIF1A/PYGL/PRCP/IRS2/PPP3CA/PTPN2	17
GO:0007272	ensheathment of neurons	10/896	136/18722	0.117280837232895	0.249377610158743	TYMP/TNFRSF1B/TLR2/CXCR4/ITGAX/MBP/PTEN/DICER1/QKI/PLEC	10
GO:0008366	axon ensheathment	10/896	136/18722	0.117280837232895	0.249377610158743	TYMP/TNFRSF1B/TLR2/CXCR4/ITGAX/MBP/PTEN/DICER1/QKI/PLEC	10
GO:0043624	cellular protein complex disassembly	10/896	136/18722	0.117280837232895	0.249377610158743	PLEK/CAPG/CFL1/CAPZA1/MTPN/CAPZA2/TWF2/FLII/TAOK1/CIB1	10
GO:1903510	mucopolysaccharide metabolic process	7/896	86/18722	0.117462100875781	0.249660967165892	IL1B/CD44/TGFB1/CSGALNACT2/GNS/DSE/NFKB1	7
GO:0048608	reproductive structure development	26/896	424/18722	0.117556994138274	0.2497605908959	JUNB/CRIP1/TNFSF10/FLNA/PTGS2/ARRB2/PSAP/SOCS3/RETN/CEBPB/PTPN6/NOTCH2/MGST1/ZFP36L1/CTSB/STK4/GRB2/PTEN/HIF1A/MAPK1/ARID4A/NCOA4/NIPBL/KDM5A/SP3/BIRC2	26
GO:0019233	sensory perception of pain	8/896	103/18722	0.120316467984765	0.255518966920686	CCL3/PTGS2/ARRB2/CCR2/CXCR4/PTAFR/FYN/MAPK1	8
GO:0050770	regulation of axonogenesis	11/896	154/18722	0.120634452835289	0.256089709876057	PLXNC1/ARHGAP4/SKIL/NIN/SHTN1/PAK1/PAK2/TWF2/PTEN/PLXNB2/DBNL	11
GO:0006986	response to unfolded protein	10/896	137/18722	0.121436816793041	0.257508325428781	SERP1/HSPA1A/PPP1R15A/PPP1R15B/CREBRF/ATF3/PTPN2/TMBIM6/EP300/HERPUD1	10
GO:0010977	negative regulation of neuron projection development	10/896	137/18722	0.121436816793041	0.257508325428781	VIM/LGALS1/B2M/LRRK2/FLNA/CTSZ/RHOA/ARHGAP4/PTEN/CIB1	10
GO:0007052	mitotic spindle organization	9/896	120/18722	0.121451244429302	0.257508325428781	FLNA/RHOA/HSPA1A/SUN2/STAG2/HNRNPU/CHMP1B/NUP62/ZNF207	9
GO:0008333	endosome to lysosome transport	5/896	55/18722	0.121976170382685	0.25830539990242	LYST/RHOB/DTX3L/M6PR/HOOK3	5
GO:0045620	negative regulation of lymphocyte differentiation	5/896	55/18722	0.121976170382685	0.25830539990242	FGL2/CD74/IRF1/BCL6/PTPN2	5
GO:0051898	negative regulation of protein kinase B signaling	5/896	55/18722	0.121976170382685	0.25830539990242	KLF4/ARRB2/SH2B3/PTEN/CIB1	5
GO:0019915	lipid storage	7/896	87/18722	0.122803723431013	0.259466944178968	IL1B/NFKBIA/CD36/TNF/OSBPL8/PTPN2/NFKB1	7
GO:0061014	positive regulation of mRNA catabolic process	7/896	87/18722	0.122803723431013	0.259466944178968	ZFP36/ZFP36L2/BTG2/PABPC1/ZFP36L1/ROCK1/CELF1	7
GO:0044275	cellular carbohydrate catabolic process	4/896	40/18722	0.122873886466602	0.259466944178968	AOAH/PGD/PYGL/RB1CC1	4
GO:0045022	early endosome to late endosome transport	4/896	40/18722	0.122873886466602	0.259466944178968	MSN/FLNA/MAPK1/HOOK3	4
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	4/896	40/18722	0.122873886466602	0.259466944178968	DUSP1/ATM/ZNF207/DYNC1LI1	4
GO:0071526	semaphorin-plexin signaling pathway	4/896	40/18722	0.122873886466602	0.259466944178968	FLNA/PLXNC1/PLXNB2/ARHGDIA	4
GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	4/896	40/18722	0.122873886466602	0.259466944178968	BID/HSPA1A/CHCHD10/BNIP3L	4
GO:0000281	mitotic cytokinesis	6/896	71/18722	0.123782556604528	0.260261336446939	RHOB/RHOA/ROCK1/CHMP1B/NUP62/SNX18	6
GO:0061458	reproductive system development	26/896	427/18722	0.124494234468546	0.260261336446939	JUNB/CRIP1/TNFSF10/FLNA/PTGS2/ARRB2/PSAP/SOCS3/RETN/CEBPB/PTPN6/NOTCH2/MGST1/ZFP36L1/CTSB/STK4/GRB2/PTEN/HIF1A/MAPK1/ARID4A/NCOA4/NIPBL/KDM5A/SP3/BIRC2	26
GO:0009755	hormone-mediated signaling pathway	13/896	190/18722	0.124601320840384	0.260261336446939	JAK2/RHOA/ACSL1/PKN1/PAK1/DDX5/RXRA/NCOA4/PRCP/ZBTB7A/ARID1A/NR3C1/EP300	13
GO:0032963	collagen metabolic process	8/896	104/18722	0.12523160712145	0.260261336446939	CTSS/VIM/CST3/ARRB2/TGFB1/CTSB/RAP1A/HIF1A	8
GO:0002418	immune response to tumor cell	3/896	26/18722	0.125893638792763	0.260261336446939	HLA-A/HLA-DRB1/AHR	3
GO:0009435	NAD biosynthetic process	3/896	26/18722	0.125893638792763	0.260261336446939	NAMPT/PARP9/KYNU	3
GO:0021952	central nervous system projection neuron axonogenesis	3/896	26/18722	0.125893638792763	0.260261336446939	NR4A2/NIN/MYCBP2	3
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	3/896	26/18722	0.125893638792763	0.260261336446939	FKBP1A/CALM2/PRKACA	3
GO:0060669	embryonic placenta morphogenesis	3/896	26/18722	0.125893638792763	0.260261336446939	SOCS3/ZFP36L1/GRB2	3
GO:1902656	calcium ion import into cytosol	3/896	26/18722	0.125893638792763	0.260261336446939	SLC8A1/FYN/PRNP	3
GO:2000108	positive regulation of leukocyte apoptotic process	3/896	26/18722	0.125893638792763	0.260261336446939	LYN/MEF2C/LGALS9	3
GO:0002430	complement receptor mediated signaling pathway	2/896	13/18722	0.125959841896271	0.260261336446939	FPR1/C5AR1	2
GO:0002551	mast cell chemotaxis	2/896	13/18722	0.125959841896271	0.260261336446939	RAC2/RIN3	2
GO:0002638	negative regulation of immunoglobulin production	2/896	13/18722	0.125959841896271	0.260261336446939	BCL6/TMBIM6	2
GO:0003334	keratinocyte development	2/896	13/18722	0.125959841896271	0.260261336446939	FOSL2/PLEC	2
GO:0006983	ER overload response	2/896	13/18722	0.125959841896271	0.260261336446939	BID/PPP1R15B	2
GO:0007183	SMAD protein complex assembly	2/896	13/18722	0.125959841896271	0.260261336446939	TGFB1/FKBP1A	2
GO:0009134	nucleoside diphosphate catabolic process	2/896	13/18722	0.125959841896271	0.260261336446939	ENTPD1/NUDT16	2
GO:0009143	nucleoside triphosphate catabolic process	2/896	13/18722	0.125959841896271	0.260261336446939	SAMHD1/NUDT16	2
GO:0030497	fatty acid elongation	2/896	13/18722	0.125959841896271	0.260261336446939	HACD4/ELOVL5	2
GO:0031053	primary miRNA processing	2/896	13/18722	0.125959841896271	0.260261336446939	STAT3/DDX3X	2
GO:0031272	regulation of pseudopodium assembly	2/896	13/18722	0.125959841896271	0.260261336446939	CDC42EP3/CDC42	2
GO:0031274	positive regulation of pseudopodium assembly	2/896	13/18722	0.125959841896271	0.260261336446939	CDC42EP3/CDC42	2
GO:0032352	positive regulation of hormone metabolic process	2/896	13/18722	0.125959841896271	0.260261336446939	EGR1/HIF1A	2
GO:0032905	transforming growth factor beta1 production	2/896	13/18722	0.125959841896271	0.260261336446939	TYROBP/ATP6AP2	2
GO:0042308	negative regulation of protein import into nucleus	2/896	13/18722	0.125959841896271	0.260261336446939	CD36/CHP1	2
GO:0042362	fat-soluble vitamin biosynthetic process	2/896	13/18722	0.125959841896271	0.260261336446939	TNF/NFKB1	2
GO:0042541	hemoglobin biosynthetic process	2/896	13/18722	0.125959841896271	0.260261336446939	KLF4/HIF1A	2
GO:0042761	very long-chain fatty acid biosynthetic process	2/896	13/18722	0.125959841896271	0.260261336446939	HACD4/ELOVL5	2
GO:0046512	sphingosine biosynthetic process	2/896	13/18722	0.125959841896271	0.260261336446939	SPTLC2/ASAH1	2
GO:0046520	sphingoid biosynthetic process	2/896	13/18722	0.125959841896271	0.260261336446939	SPTLC2/ASAH1	2
GO:0046642	negative regulation of alpha-beta T cell proliferation	2/896	13/18722	0.125959841896271	0.260261336446939	LGALS9/TNFRSF14	2
GO:0046689	response to mercury ion	2/896	13/18722	0.125959841896271	0.260261336446939	AQP9/UBE2D3	2
GO:0048012	hepatocyte growth factor receptor signaling pathway	2/896	13/18722	0.125959841896271	0.260261336446939	PAK1/PTPN2	2
GO:0048070	regulation of developmental pigmentation	2/896	13/18722	0.125959841896271	0.260261336446939	ZEB2/BLOC1S6	2
GO:0048266	behavioral response to pain	2/896	13/18722	0.125959841896271	0.260261336446939	TSPO/CAPN2	2
GO:0051451	myoblast migration	2/896	13/18722	0.125959841896271	0.260261336446939	PLEKHO1/ROCK1	2
GO:0051709	regulation of killing of cells of other organism	2/896	13/18722	0.125959841896271	0.260261336446939	CLEC7A/SYK	2
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	2/896	13/18722	0.125959841896271	0.260261336446939	CDC42/HNRNPU	2
GO:0060100	positive regulation of phagocytosis, engulfment	2/896	13/18722	0.125959841896271	0.260261336446939	CD36/NCKAP1L	2
GO:0060670	branching involved in labyrinthine layer morphogenesis	2/896	13/18722	0.125959841896271	0.260261336446939	SOCS3/GRB2	2
GO:0072310	glomerular epithelial cell development	2/896	13/18722	0.125959841896271	0.260261336446939	IQGAP1/NOTCH2	2
GO:0072672	neutrophil extravasation	2/896	13/18722	0.125959841896271	0.260261336446939	JAML/PECAM1	2
GO:0090042	tubulin deacetylation	2/896	13/18722	0.125959841896271	0.260261336446939	FLNA/EP300	2
GO:0120305	regulation of pigmentation	2/896	13/18722	0.125959841896271	0.260261336446939	ZEB2/BLOC1S6	2
GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	2/896	13/18722	0.125959841896271	0.260261336446939	PLXNC1/PLXNB2	2
GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	2/896	13/18722	0.125959841896271	0.260261336446939	TMSB4X/EP300	2
GO:1903651	positive regulation of cytoplasmic transport	2/896	13/18722	0.125959841896271	0.260261336446939	MSN/SORL1	2
GO:1904590	negative regulation of protein import	2/896	13/18722	0.125959841896271	0.260261336446939	CD36/CHP1	2
GO:1904925	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	2/896	13/18722	0.125959841896271	0.260261336446939	VPS13C/TOMM7	2
GO:1905155	positive regulation of membrane invagination	2/896	13/18722	0.125959841896271	0.260261336446939	CD36/NCKAP1L	2
GO:1905203	regulation of connective tissue replacement	2/896	13/18722	0.125959841896271	0.260261336446939	ROCK1/PPP3CA	2
GO:1905244	regulation of modification of synaptic structure	2/896	13/18722	0.125959841896271	0.260261336446939	RHOA/CDC42	2
GO:2000318	positive regulation of T-helper 17 type immune response	2/896	13/18722	0.125959841896271	0.260261336446939	NFKBIZ/CLEC7A	2
GO:0001704	formation of primary germ layer	9/896	121/18722	0.126002315934126	0.260261336446939	ITGB2/DUSP1/KLF4/ITGA4/ITGA5/PRKACA/PRKAR1A/KDM6B/ETS2	9
GO:0000910	cytokinesis	12/896	173/18722	0.126780418843618	0.261764572610423	RHOB/ACTR2/RHOA/ACTR3/CALM2/CDC42/ROCK1/MYH9/PLEC/CHMP1B/NUP62/SNX18	12
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	5/896	56/18722	0.128993944689366	0.26570198270471	ZFP36/ZFP36L2/BTG2/PABPC1/ZFP36L1	5
GO:0022029	telencephalon cell migration	5/896	56/18722	0.128993944689366	0.26570198270471	LRRK2/CXCR4/RHOA/SUN2/MBOAT7	5
GO:0031122	cytoplasmic microtubule organization	5/896	56/18722	0.128993944689366	0.26570198270471	CCDC88A/RHOA/CHP1/HOOK3/CIB1	5
GO:0048008	platelet-derived growth factor receptor signaling pathway	5/896	56/18722	0.128993944689366	0.26570198270471	TXNIP/JAK2/ZFAND5/PTEN/PTPN2	5
GO:0051653	spindle localization	5/896	56/18722	0.128993944689366	0.26570198270471	ACTR2/ACTR3/CFL1/MYH9/DYNLT1	5
GO:0051784	negative regulation of nuclear division	5/896	56/18722	0.128993944689366	0.26570198270471	DUSP1/PRKAR1A/ATM/ZNF207/DYNC1LI1	5
GO:0033045	regulation of sister chromatid segregation	6/896	72/18722	0.129925990671916	0.267256539472642	DUSP1/RB1/ATM/HNRNPU/ZNF207/DYNC1LI1	6
GO:1903036	positive regulation of response to wounding	6/896	72/18722	0.129925990671916	0.267256539472642	CLEC7A/FLNA/CD36/GRN/HBEGF/CXCR4	6
GO:1905818	regulation of chromosome separation	6/896	72/18722	0.129925990671916	0.267256539472642	DUSP1/PLSCR1/RB1/ATM/ZNF207/DYNC1LI1	6
GO:0051783	regulation of nuclear division	10/896	139/18722	0.129988588712483	0.267256539472642	IL1B/DUSP1/CDC42/PRKAR1A/RB1/ATM/PHIP/NUP62/ZNF207/DYNC1LI1	10
GO:0046486	glycerolipid metabolic process	24/896	392/18722	0.130005584477174	0.267256539472642	PLEK/SOCS3/GPCPD1/GPX1/PLSCR1/SORL1/CSF1R/LPGAT1/LPCAT2/PLCB2/INPP5D/APOBR/ACSL1/OSBPL8/CAPN2/NAAA/PTEN/DGKZ/ACSL4/MBOAT7/ATM/PIP4K2A/FAR1/SMG1	24
GO:0001953	negative regulation of cell-matrix adhesion	4/896	41/18722	0.131315547747071	0.269629752796098	BCL6/PTEN/CORO1C/DUSP22	4
GO:0048634	regulation of muscle organ development	4/896	41/18722	0.131315547747071	0.269629752796098	MEF2C/TGFB1/MTPN/CREB1	4
GO:0070296	sarcoplasmic reticulum calcium ion transport	4/896	41/18722	0.131315547747071	0.269629752796098	CCL3/SLC8A1/CALM2/PRKACA	4
GO:0001837	epithelial to mesenchymal transition	11/896	157/18722	0.132729165689418	0.272424779301761	S100A4/IL1B/FLNA/GLIPR2/TGFB1/DDX5/ROCK1/SDCBP/PTEN/HIF1A/TGFBR2	11
GO:0046165	alcohol biosynthetic process	10/896	140/18722	0.134382990941483	0.275710428357654	PLEK/PTAFR/GCH1/PTK2B/SPTLC2/G6PD/ASAH1/LBR/PPIP5K2/NFKB1	10
GO:0006754	ATP biosynthetic process	5/896	57/18722	0.136190794314013	0.279024410586414	TMSB4X/TGFB1/PRKAG2/ATP6V1A/STAT3	5
GO:0051289	protein homotetramerization	5/896	57/18722	0.136190794314013	0.279024410586414	SAMHD1/SOD2/B2M/VASP/GBP5	5
GO:0009166	nucleotide catabolic process	6/896	73/18722	0.13621283954603	0.279024410586414	TYMP/SAMHD1/DPYD/UPP1/NUDT16/NUDT3	6
GO:0051865	protein autoubiquitination	6/896	73/18722	0.13621283954603	0.279024410586414	LRRK2/RNF213/DTX3L/UBE2D3/RNF141/RNF13	6
GO:0001835	blastocyst hatching	3/896	27/18722	0.136872414924332	0.279056617021345	LPAR6/CMTM3/SMIM14	3
GO:0002825	regulation of T-helper 1 type immune response	3/896	27/18722	0.136872414924332	0.279056617021345	IL1B/SLC11A1/CCR2	3
GO:0009651	response to salt stress	3/896	27/18722	0.136872414924332	0.279056617021345	TNF/ZFP36L1/MICU1	3
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	3/896	27/18722	0.136872414924332	0.279056617021345	SLC8A1/CALM2/PRKACA	3
GO:0018904	ether metabolic process	3/896	27/18722	0.136872414924332	0.279056617021345	ALOX5/LPCAT2/FAR1	3
GO:0032967	positive regulation of collagen biosynthetic process	3/896	27/18722	0.136872414924332	0.279056617021345	VIM/ARRB2/TGFB1	3
GO:0035188	hatching	3/896	27/18722	0.136872414924332	0.279056617021345	LPAR6/CMTM3/SMIM14	3
GO:0042402	cellular biogenic amine catabolic process	3/896	27/18722	0.136872414924332	0.279056617021345	SAT1/KYNU/HNMT	3
GO:0045830	positive regulation of isotype switching	3/896	27/18722	0.136872414924332	0.279056617021345	PTPRC/TGFB1/STAT6	3
GO:0048873	homeostasis of number of cells within a tissue	3/896	27/18722	0.136872414924332	0.279056617021345	CORO1A/CCR2/LIPA	3
GO:0071684	organism emergence from protective structure	3/896	27/18722	0.136872414924332	0.279056617021345	LPAR6/CMTM3/SMIM14	3
GO:1903203	regulation of oxidative stress-induced neuron death	3/896	27/18722	0.136872414924332	0.279056617021345	MCL1/TLR4/HIF1A	3
GO:0048284	organelle fusion	10/896	141/18722	0.138855376126774	0.282988562396298	CORO1A/STX11/SAMD9/STX10/RAB8B/CHP1/PIP4K2A/GNAI3/STX7/STX12	10
GO:0006040	amino sugar metabolic process	4/896	42/18722	0.139988752457245	0.284568442910873	ALDH1A1/NAGK/MGAT1/CTBS	4
GO:0032965	regulation of collagen biosynthetic process	4/896	42/18722	0.139988752457245	0.284568442910873	VIM/ARRB2/TGFB1/RAP1A	4
GO:0042168	heme metabolic process	4/896	42/18722	0.139988752457245	0.284568442910873	TSPO/BLVRB/BLVRA/HMOX1	4
GO:0045773	positive regulation of axon extension	4/896	42/18722	0.139988752457245	0.284568442910873	SHTN1/PAK1/TWF2/DBNL	4
GO:0090317	negative regulation of intracellular protein transport	4/896	42/18722	0.139988752457245	0.284568442910873	LRRK2/CD36/SP100/CHP1	4
GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	4/896	42/18722	0.139988752457245	0.284568442910873	DUSP1/ATM/ZNF207/DYNC1LI1	4
GO:0005976	polysaccharide metabolic process	8/896	107/18722	0.1405915954921	0.284568442910873	AOAH/TGFB1/CSGALNACT2/PRKAG2/PYGL/IRS2/RB1CC1/NFKB1	8
GO:0010927	cellular component assembly involved in morphogenesis	8/896	107/18722	0.1405915954921	0.284568442910873	TLR2/AKAP13/MEF2A/PRKAR1A/CFLAR/FLII/DICER1/PLEC	8
GO:0046488	phosphatidylinositol metabolic process	11/896	159/18722	0.141144262675377	0.284568442910873	PLEK/SOCS3/CSF1R/LPGAT1/PLCB2/INPP5D/PTEN/MBOAT7/ATM/PIP4K2A/SMG1	11
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	2/896	14/18722	0.142490608114327	0.284568442910873	HLA-E/BTK	2
GO:0006465	signal peptide processing	2/896	14/18722	0.142490608114327	0.284568442910873	SEC11A/SPCS3	2
GO:0006596	polyamine biosynthetic process	2/896	14/18722	0.142490608114327	0.284568442910873	OAZ1/SAT1	2
GO:0009158	ribonucleoside monophosphate catabolic process	2/896	14/18722	0.142490608114327	0.284568442910873	DPYD/UPP1	2
GO:0009173	pyrimidine ribonucleoside monophosphate metabolic process	2/896	14/18722	0.142490608114327	0.284568442910873	DPYD/UPP1	2
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	2/896	14/18722	0.142490608114327	0.284568442910873	GBP1/CORO1C	2
GO:0019321	pentose metabolic process	2/896	14/18722	0.142490608114327	0.284568442910873	G6PD/PGD	2
GO:0031054	pre-miRNA processing	2/896	14/18722	0.142490608114327	0.284568442910873	ADAR/DICER1	2
GO:0033008	positive regulation of mast cell activation involved in immune response	2/896	14/18722	0.142490608114327	0.284568442910873	FGR/SYK	2
GO:0033169	histone H3-K9 demethylation	2/896	14/18722	0.142490608114327	0.284568442910873	JMJD1C/KDM7A	2
GO:0034616	response to laminar fluid shear stress	2/896	14/18722	0.142490608114327	0.284568442910873	KLF2/KLF4	2
GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	2/896	14/18722	0.142490608114327	0.284568442910873	P2RY13/PTAFR	2
GO:0036151	phosphatidylcholine acyl-chain remodeling	2/896	14/18722	0.142490608114327	0.284568442910873	LPCAT2/MBOAT7	2
GO:0036295	cellular response to increased oxygen levels	2/896	14/18722	0.142490608114327	0.284568442910873	ATP6V0D1/ATP6V1A	2
GO:0038166	angiotensin-activated signaling pathway	2/896	14/18722	0.142490608114327	0.284568442910873	AGTRAP/ROCK1	2
GO:0042921	glucocorticoid receptor signaling pathway	2/896	14/18722	0.142490608114327	0.284568442910873	ARID1A/NR3C1	2
GO:0043306	positive regulation of mast cell degranulation	2/896	14/18722	0.142490608114327	0.284568442910873	FGR/SYK	2
GO:0043374	CD8-positive, alpha-beta T cell differentiation	2/896	14/18722	0.142490608114327	0.284568442910873	IRF1/NCKAP1L	2
GO:0043558	regulation of translational initiation in response to stress	2/896	14/18722	0.142490608114327	0.284568442910873	PPP1R15A/PPP1R15B	2
GO:0045820	negative regulation of glycolytic process	2/896	14/18722	0.142490608114327	0.284568442910873	FBP1/STAT3	2
GO:0046049	UMP metabolic process	2/896	14/18722	0.142490608114327	0.284568442910873	DPYD/UPP1	2
GO:0046325	negative regulation of glucose import	2/896	14/18722	0.142490608114327	0.284568442910873	TNF/PEA15	2
GO:0047484	regulation of response to osmotic stress	2/896	14/18722	0.142490608114327	0.284568442910873	PTGS2/MICU1	2
GO:0048875	chemical homeostasis within a tissue	2/896	14/18722	0.142490608114327	0.284568442910873	CTSH/OAS1	2
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	2/896	14/18722	0.142490608114327	0.284568442910873	CXCR4/FYN	2
GO:0051547	regulation of keratinocyte migration	2/896	14/18722	0.142490608114327	0.284568442910873	HBEGF/PTEN	2
GO:0051589	negative regulation of neurotransmitter transport	2/896	14/18722	0.142490608114327	0.284568442910873	RAP1A/RAP1B	2
GO:0051645	Golgi localization	2/896	14/18722	0.142490608114327	0.284568442910873	CDC42/HOOK3	2
GO:0055057	neuroblast division	2/896	14/18722	0.142490608114327	0.284568442910873	NUMB/RAB10	2
GO:0060081	membrane hyperpolarization	2/896	14/18722	0.142490608114327	0.284568442910873	SOD2/CASP1	2
GO:0060576	intestinal epithelial cell development	2/896	14/18722	0.142490608114327	0.284568442910873	CDKN1A/HIF1A	2
GO:0070278	extracellular matrix constituent secretion	2/896	14/18722	0.142490608114327	0.284568442910873	TNFRSF1B/TNFRSF1A	2
GO:0070942	neutrophil mediated cytotoxicity	2/896	14/18722	0.142490608114327	0.284568442910873	TREM1/MYD88	2
GO:0071481	cellular response to X-ray	2/896	14/18722	0.142490608114327	0.284568442910873	NIPBL/ATM	2
GO:0072160	nephron tubule epithelial cell differentiation	2/896	14/18722	0.142490608114327	0.284568442910873	STAT1/MEF2C	2
GO:0072540	T-helper 17 cell lineage commitment	2/896	14/18722	0.142490608114327	0.284568442910873	IL6R/STAT3	2
GO:0097531	mast cell migration	2/896	14/18722	0.142490608114327	0.284568442910873	RAC2/RIN3	2
GO:0099188	postsynaptic cytoskeleton organization	2/896	14/18722	0.142490608114327	0.284568442910873	ACTB/DBNL	2
GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	2/896	14/18722	0.142490608114327	0.284568442910873	GBP1/CORO1C	2
GO:1904923	regulation of autophagy of mitochondrion in response to mitochondrial depolarization	2/896	14/18722	0.142490608114327	0.284568442910873	VPS13C/TOMM7	2
GO:2001171	positive regulation of ATP biosynthetic process	2/896	14/18722	0.142490608114327	0.284568442910873	TMSB4X/STAT3	2
GO:0030324	lung development	12/896	177/18722	0.142543560503558	0.284568442910873	KLF2/CTSH/CTSZ/TNF/EIF4EBP1/CDC42/LIPA/MAPK1/TGFBR2/EP300/SP3/CREB1	12
GO:0051648	vesicle localization	12/896	177/18722	0.142543560503558	0.284568442910873	LRRK2/MYO1F/ITGA4/MYO1G/TCIRG1/RAB27A/BLOC1S1/CHP1/PICALM/PTEN/FAM91A1/BLOC1S6	12
GO:0010822	positive regulation of mitochondrion organization	6/896	74/18722	0.142639863616352	0.284568442910873	PYCARD/TNFSF10/PLAUR/BID/CHCHD10/HIF1A	6
GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	6/896	74/18722	0.142639863616352	0.284568442910873	RHOA/PKN1/PAK1/DDX5/ZBTB7A/EP300	6
GO:1901568	fatty acid derivative metabolic process	6/896	74/18722	0.142639863616352	0.284568442910873	PPT1/ALOX5/ACSL1/ELOVL5/ACSL4/FAR1	6
GO:1901988	negative regulation of cell cycle phase transition	16/896	249/18722	0.14273670194703	0.284652448936542	DUSP1/ZFP36L2/KLF4/ZFP36L1/TAOK3/CDKN1A/PTEN/RB1/ATM/NABP1/FOXN3/TAOK1/WAC/CTDSP1/ZNF207/DYNC1LI1	16
GO:0030705	cytoskeleton-dependent intracellular transport	13/896	195/18722	0.143266970181665	0.2856004261843	MYO1F/TUBA1A/MYO1G/CCDC88A/BLOC1S1/AGTPBP1/CDC42/HIF1A/SUN2/BICD2/HNRNPU/HOOK3/BLOC1S6	13
GO:0001505	regulation of neurotransmitter levels	14/896	213/18722	0.14346888384873	0.285893358198178	STXBP2/LRRK2/NR4A1/MEF2C/PPT1/PRKCB/STX11/MCTP1/AGTPBP1/RAP1A/HNMT/RAP1B/CTBP2/BLOC1S6	14
GO:1902808	positive regulation of cell cycle G1/S phase transition	5/896	58/18722	0.143561322239879	0.285967995775416	AIF1/KMT2E/LSM10/ADAM17/DDX3X	5
GO:0051053	negative regulation of DNA metabolic process	9/896	125/18722	0.145094521538772	0.288800844440548	DUSP1/BCL6/SMCHD1/CDKN1A/ATM/HNRNPU/XRN1/KMT2A/TRIP12	9
GO:0070585	protein localization to mitochondrion	9/896	125/18722	0.145094521538772	0.288800844440548	TSPO/LRRK2/ISG15/RAC2/BID/BNIP3L/UBE2D3/TOMM7/OXA1L	9
GO:0051983	regulation of chromosome segregation	7/896	91/18722	0.145369968623883	0.289238411175523	DUSP1/PLSCR1/RB1/ATM/HNRNPU/ZNF207/DYNC1LI1	7
GO:0033138	positive regulation of peptidyl-serine phosphorylation	8/896	108/18722	0.145911586776854	0.290205033585628	CD44/PTGS2/ARRB2/TGFB1/TNF/HCLS1/STK4/PAK1	8
GO:0006006	glucose metabolic process	13/896	196/18722	0.147172602445543	0.29260118704865	OAS1/TNF/SERP1/FBP1/MIDN/PDK4/G6PD/PGK1/ATF3/ADPGK/IRS2/PTPN2/EP300	13
GO:0010464	regulation of mesenchymal cell proliferation	3/896	28/18722	0.14816311866917	0.293784361493844	STAT1/TGFBR2/IRS2	3
GO:0010714	positive regulation of collagen metabolic process	3/896	28/18722	0.14816311866917	0.293784361493844	VIM/ARRB2/TGFB1	3
GO:0032801	receptor catabolic process	3/896	28/18722	0.14816311866917	0.293784361493844	LAPTM5/TGFB1/DTX3L	3
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	3/896	28/18722	0.14816311866917	0.293784361493844	PTPN2/MVP/NUP62	3
GO:0051894	positive regulation of focal adhesion assembly	3/896	28/18722	0.14816311866917	0.293784361493844	IQGAP1/ROCK1/LIMS1	3
GO:0060325	face morphogenesis	3/896	28/18722	0.14816311866917	0.293784361493844	RRAS/NIPBL/EP300	3
GO:1903672	positive regulation of sprouting angiogenesis	3/896	28/18722	0.14816311866917	0.293784361493844	KLF4/JAK1/ITGA5	3
GO:0009268	response to pH	4/896	43/18722	0.148883108886927	0.294426254494641	CTSS/HVCN1/GPR65/CHP1	4
GO:0010171	body morphogenesis	4/896	43/18722	0.148883108886927	0.294426254494641	RRAS/ATP6AP2/NIPBL/EP300	4
GO:0033046	negative regulation of sister chromatid segregation	4/896	43/18722	0.148883108886927	0.294426254494641	DUSP1/ATM/ZNF207/DYNC1LI1	4
GO:0033048	negative regulation of mitotic sister chromatid segregation	4/896	43/18722	0.148883108886927	0.294426254494641	DUSP1/ATM/ZNF207/DYNC1LI1	4
GO:0035794	positive regulation of mitochondrial membrane permeability	4/896	43/18722	0.148883108886927	0.294426254494641	BID/HSPA1A/CHCHD10/BNIP3L	4
GO:0045840	positive regulation of mitotic nuclear division	4/896	43/18722	0.148883108886927	0.294426254494641	IL1B/RB1/PHIP/NUP62	4
GO:2000816	negative regulation of mitotic sister chromatid separation	4/896	43/18722	0.148883108886927	0.294426254494641	DUSP1/ATM/ZNF207/DYNC1LI1	4
GO:0006650	glycerophospholipid metabolic process	19/896	306/18722	0.14908748368368	0.294612063937736	PLEK/SOCS3/GPCPD1/PLSCR1/CSF1R/LPGAT1/LPCAT2/PLCB2/INPP5D/OSBPL8/CAPN2/NAAA/PTEN/DGKZ/MBOAT7/ATM/PIP4K2A/FAR1/SMG1	19
GO:0043627	response to estrogen	6/896	75/18722	0.149203648608344	0.294612063937736	ARPC1B/MAPK1/NCOA4/HMOX1/TGFBR2/EP300	6
GO:1902369	negative regulation of RNA catabolic process	6/896	75/18722	0.149203648608344	0.294612063937736	ZFP36/SLC11A1/PABPC1/MYD88/YBX1/HNRNPU	6
GO:2001259	positive regulation of cation channel activity	6/896	75/18722	0.149203648608344	0.294612063937736	CTSS/TMSB4X/IFNGR2/CCR2/KCNE3/CALM2	6
GO:0051650	establishment of vesicle localization	11/896	161/18722	0.149834876912699	0.295746183993528	LRRK2/MYO1F/ITGA4/MYO1G/TCIRG1/RAB27A/BLOC1S1/CHP1/PICALM/FAM91A1/BLOC1S6	11
GO:0001936	regulation of endothelial cell proliferation	12/896	179/18722	0.150801056810213	0.297540324912715	CYBA/STAT1/NR4A1/MEF2C/ITGA4/TNF/ALOX5/STAT3/HIF1A/HMOX1/SP1/ADAM17	12
GO:0019369	arachidonic acid metabolic process	5/896	59/18722	0.151099890035211	0.297791029963295	PTGS2/CYP1B1/GPX1/ALOX5/TBXAS1	5
GO:0021885	forebrain cell migration	5/896	59/18722	0.151099890035211	0.297791029963295	LRRK2/CXCR4/RHOA/SUN2/MBOAT7	5
GO:0051568	histone H3-K4 methylation	5/896	59/18722	0.151099890035211	0.297791029963295	KMT2E/ARID4A/TET2/KMT2C/KMT2A	5
GO:0033135	regulation of peptidyl-serine phosphorylation	10/896	144/18722	0.152731689458284	0.300892998815353	CD44/PTGS2/ARRB2/TGFB1/RASSF2/TNF/HCLS1/STK4/PAK1/PTEN	10
GO:0006305	DNA alkylation	6/896	76/18722	0.15590061614637	0.306903521793063	FOS/SPI1/KDM1B/KMT2E/MBD2/KMT2A	6
GO:0006306	DNA methylation	6/896	76/18722	0.15590061614637	0.306903521793063	FOS/SPI1/KDM1B/KMT2E/MBD2/KMT2A	6
GO:0018958	phenol-containing compound metabolic process	8/896	110/18722	0.156841810158296	0.307823468945229	ITGB2/ZEB2/NR4A2/SULT1A1/ITGAM/GCH1/CTSB/MTPN	8
GO:1901796	regulation of signal transduction by p53 class mediator	7/896	93/18722	0.157342708731704	0.307823468945229	CD74/CD44/SGK1/DDX5/ZNF385A/ATM/EP300	7
GO:1902807	negative regulation of cell cycle G1/S phase transition	7/896	93/18722	0.157342708731704	0.307823468945229	KLF4/CDKN1A/PTEN/RB1/ATM/WAC/CTDSP1	7
GO:0002792	negative regulation of peptide secretion	4/896	44/18722	0.157987943816573	0.307823468945229	CD74/UCP2/MIDN/PPP3CA	4
GO:0046006	regulation of activated T cell proliferation	4/896	44/18722	0.157987943816573	0.307823468945229	PYCARD/LGALS9/PRKAR1A/PRNP	4
GO:0006633	fatty acid biosynthetic process	11/896	163/18722	0.158794987042625	0.307823468945229	IL1B/CD74/PTGS2/HACD4/ALOX5/TBXAS1/LPGAT1/PDK4/PRKAG2/ELOVL5/QKI	11
GO:0030071	regulation of mitotic metaphase/anaphase transition	5/896	60/18722	0.158800639875352	0.307823468945229	DUSP1/RB1/ATM/ZNF207/DYNC1LI1	5
GO:0031638	zymogen activation	5/896	60/18722	0.158800639875352	0.307823468945229	PYCARD/IFI16/CTSH/CTSZ/PGK1	5
GO:0033866	nucleoside bisphosphate biosynthetic process	5/896	60/18722	0.158800639875352	0.307823468945229	PPT1/ACSL1/PDK4/ELOVL5/ACSL4	5
GO:0034030	ribonucleoside bisphosphate biosynthetic process	5/896	60/18722	0.158800639875352	0.307823468945229	PPT1/ACSL1/PDK4/ELOVL5/ACSL4	5
GO:0034033	purine nucleoside bisphosphate biosynthetic process	5/896	60/18722	0.158800639875352	0.307823468945229	PPT1/ACSL1/PDK4/ELOVL5/ACSL4	5
GO:0060038	cardiac muscle cell proliferation	5/896	60/18722	0.158800639875352	0.307823468945229	MEF2C/PRKAR1A/PTEN/MAPK1/TGFBR2	5
GO:0030323	respiratory tube development	12/896	181/18722	0.159302797474767	0.307823468945229	KLF2/CTSH/CTSZ/TNF/EIF4EBP1/CDC42/LIPA/MAPK1/TGFBR2/EP300/SP3/CREB1	12
GO:0099504	synaptic vesicle cycle	12/896	181/18722	0.159302797474767	0.307823468945229	LRRK2/ACTB/PRKCB/STX11/RAP1A/PICALM/ITSN2/ROCK1/PTEN/RAP1B/CTBP2/BLOC1S6	12
GO:0002070	epithelial cell maturation	2/896	15/18722	0.159442249418411	0.307823468945229	CDKN1A/HIF1A	2
GO:0010713	negative regulation of collagen metabolic process	2/896	15/18722	0.159442249418411	0.307823468945229	CST3/RAP1A	2
GO:0014744	positive regulation of muscle adaptation	2/896	15/18722	0.159442249418411	0.307823468945229	AIF1/PPP3CA	2
GO:0021542	dentate gyrus development	2/896	15/18722	0.159442249418411	0.307823468945229	BTG2/PTEN	2
GO:0031269	pseudopodium assembly	2/896	15/18722	0.159442249418411	0.307823468945229	CDC42EP3/CDC42	2
GO:0032897	negative regulation of viral transcription	2/896	15/18722	0.159442249418411	0.307823468945229	ZFP36/IFITM3	2
GO:0034310	primary alcohol catabolic process	2/896	15/18722	0.159442249418411	0.307823468945229	ALDH2/SULT1A1	2
GO:0042182	ketone catabolic process	2/896	15/18722	0.159442249418411	0.307823468945229	KYNU/NQO2	2
GO:0042994	cytoplasmic sequestering of transcription factor	2/896	15/18722	0.159442249418411	0.307823468945229	TMSB4X/NFKBIA	2
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	2/896	15/18722	0.159442249418411	0.307823468945229	CD74/CD44	2
GO:0045475	locomotor rhythm	2/896	15/18722	0.159442249418411	0.307823468945229	EGR1/PTEN	2
GO:0045986	negative regulation of smooth muscle contraction	2/896	15/18722	0.159442249418411	0.307823468945229	RGS2/PTGS2	2
GO:0051127	positive regulation of actin nucleation	2/896	15/18722	0.159442249418411	0.307823468945229	WAS/BRK1	2
GO:0051608	histamine transport	2/896	15/18722	0.159442249418411	0.307823468945229	LYN/BTK	2
GO:0051775	response to redox state	2/896	15/18722	0.159442249418411	0.307823468945229	ARHGDIB/ARHGDIA	2
GO:0055012	ventricular cardiac muscle cell differentiation	2/896	15/18722	0.159442249418411	0.307823468945229	MEF2C/MEF2A	2
GO:0060253	negative regulation of glial cell proliferation	2/896	15/18722	0.159442249418411	0.307823468945229	TSPO/DICER1	2
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	2/896	15/18722	0.159442249418411	0.307823468945229	LRRK2/SORL1	2
GO:0070071	proton-transporting two-sector ATPase complex assembly	2/896	15/18722	0.159442249418411	0.307823468945229	OXA1L/VMA21	2
GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	2/896	15/18722	0.159442249418411	0.307823468945229	CHP1/PRNP	2
GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	2/896	15/18722	0.159442249418411	0.307823468945229	TNF/CIB1	2
GO:0071474	cellular hyperosmotic response	2/896	15/18722	0.159442249418411	0.307823468945229	RCSD1/MICU1	2
GO:0099170	postsynaptic modulation of chemical synaptic transmission	2/896	15/18722	0.159442249418411	0.307823468945229	NRGN/PPP3CA	2
GO:0106057	negative regulation of calcineurin-mediated signaling	2/896	15/18722	0.159442249418411	0.307823468945229	CHP1/PRNP	2
GO:0106058	positive regulation of calcineurin-mediated signaling	2/896	15/18722	0.159442249418411	0.307823468945229	TNF/CIB1	2
GO:1900102	negative regulation of endoplasmic reticulum unfolded protein response	2/896	15/18722	0.159442249418411	0.307823468945229	PPP1R15A/PPP1R15B	2
GO:1901741	positive regulation of myoblast fusion	2/896	15/18722	0.159442249418411	0.307823468945229	CD53/CAPN2	2
GO:1903727	positive regulation of phospholipid metabolic process	2/896	15/18722	0.159442249418411	0.307823468945229	CAPN2/CHP1	2
GO:1904424	regulation of GTP binding	2/896	15/18722	0.159442249418411	0.307823468945229	C9orf72/CCPG1	2
GO:1905146	lysosomal protein catabolic process	2/896	15/18722	0.159442249418411	0.307823468945229	TPP1/LAMP2	2
GO:1905168	positive regulation of double-strand break repair via homologous recombination	2/896	15/18722	0.159442249418411	0.307823468945229	ACTR2/WAS	2
GO:1905288	vascular associated smooth muscle cell apoptotic process	2/896	15/18722	0.159442249418411	0.307823468945229	SOD2/STK4	2
GO:1905459	regulation of vascular associated smooth muscle cell apoptotic process	2/896	15/18722	0.159442249418411	0.307823468945229	SOD2/STK4	2
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	3/896	29/18722	0.159741500227489	0.307823468945229	ZFP36/BTG2/PABPC1	3
GO:0009310	amine catabolic process	3/896	29/18722	0.159741500227489	0.307823468945229	SAT1/KYNU/HNMT	3
GO:0019082	viral protein processing	3/896	29/18722	0.159741500227489	0.307823468945229	PARP9/MGAT1/SPCS3	3
GO:0040018	positive regulation of multicellular organism growth	3/896	29/18722	0.159741500227489	0.307823468945229	NIPBL/CELF1/CREB1	3
GO:0048265	response to pain	3/896	29/18722	0.159741500227489	0.307823468945229	TSPO/GCH1/CAPN2	3
GO:0060441	epithelial tube branching involved in lung morphogenesis	3/896	29/18722	0.159741500227489	0.307823468945229	CTSH/CTSZ/TNF	3
GO:0072539	T-helper 17 cell differentiation	3/896	29/18722	0.159741500227489	0.307823468945229	NFKBIZ/IL6R/STAT3	3
GO:1901017	negative regulation of potassium ion transmembrane transporter activity	3/896	29/18722	0.159741500227489	0.307823468945229	KCNE3/PTEN/CAB39	3
GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	3/896	29/18722	0.159741500227489	0.307823468945229	CD74/CD44/ZNF385A	3
GO:2001032	regulation of double-strand break repair via nonhomologous end joining	3/896	29/18722	0.159741500227489	0.307823468945229	PARP9/SMCHD1/DTX3L	3
GO:0006839	mitochondrial transport	16/896	254/18722	0.160315642013131	0.308815427448257	TSPO/LRRK2/RAC2/UCP2/BID/HSPA1A/CHCHD10/BNIP3L/STAT3/MPC1/SLC25A24/UBE2D3/TOMM7/OXA1L/MICU1/DYNLT1	16
GO:0048762	mesenchymal cell differentiation	15/896	236/18722	0.161603320031867	0.311065457988802	S100A4/IL1B/FLNA/STAT1/MEF2C/GLIPR2/TGFB1/DDX5/ROCK1/SDCBP/PTEN/HIF1A/MAPK1/TGFBR2/CORO1C	15
GO:0090068	positive regulation of cell cycle process	15/896	236/18722	0.161603320031867	0.311065457988802	AIF1/IL1B/PLSCR1/RHOA/NUDT16/CDC42/KMT2E/RB1/HNRNPU/PHIP/LSM10/ADAM17/DDX3X/NUP62/DYNC1LI1	15
GO:0010675	regulation of cellular carbohydrate metabolic process	10/896	146/18722	0.162355464502028	0.312345480492393	PLEK/PTAFR/PTK2B/FBP1/MIDN/PDK4/STAT3/IRS2/PTPN2/EP300	10
GO:0001938	positive regulation of endothelial cell proliferation	8/896	111/18722	0.162448476203023	0.312345480492393	CYBA/NR4A1/ITGA4/STAT3/HIF1A/HMOX1/SP1/ADAM17	8
GO:0015718	monocarboxylic acid transport	8/896	111/18722	0.162448476203023	0.312345480492393	IL1B/CD36/SYK/SLCO3A1/AQP9/SLC16A3/MPC1/EMB	8
GO:0000380	alternative mRNA splicing, via spliceosome	6/896	77/18722	0.162727034398667	0.312649909829134	MBNL1/CELF2/DDX5/ZBTB7A/HNRNPU/CELF1	6
GO:0002200	somatic diversification of immune receptors	6/896	77/18722	0.162727034398667	0.312649909829134	PTPRC/SAMHD1/TGFB1/STAT6/BCL6/ADAR	6
GO:0099003	vesicle-mediated transport in synapse	13/896	200/18722	0.163353933748323	0.313658210355206	LRRK2/ACTB/PRKCB/NUMB/STX11/RAP1A/PICALM/ITSN2/ROCK1/PTEN/RAP1B/CTBP2/BLOC1S6	13
GO:0002042	cell migration involved in sprouting angiogenesis	7/896	94/18722	0.163493060617759	0.313658210355206	KLF4/PTGS2/NR4A1/RHOA/MAP3K3/HMOX1/CIB1	7
GO:1902414	protein localization to cell junction	7/896	94/18722	0.163493060617759	0.313658210355206	FLNA/ACTB/PECAM1/JAK1/RAP1A/PAK2/ADAM10	7
GO:1990830	cellular response to leukemia inhibitory factor	7/896	94/18722	0.163493060617759	0.313658210355206	KLF4/SNX10/SOCS3/CTBP2/HNRNPU/CREB1/MAT2A	7
GO:0009260	ribonucleotide biosynthetic process	12/896	182/18722	0.163643556557179	0.313831171701285	TMSB4X/PPT1/TGFB1/UPP1/ACSL1/PDK4/PRKAG2/ELOVL5/ATP6V1A/STAT3/ADCY7/ACSL4	12
GO:0006022	aminoglycan metabolic process	9/896	129/18722	0.165552108647492	0.317374315177149	IL1B/CD44/TGFB1/CSGALNACT2/GNS/IDS/DSE/NFKB1/CTBS	9
GO:0040014	regulation of multicellular organism growth	5/896	61/18722	0.166657516267168	0.319258100223036	PLAC8/STAT3/NIPBL/CELF1/CREB1	5
GO:0043954	cellular component maintenance	5/896	61/18722	0.166657516267168	0.319258100223036	CSF1R/FYN/CHCHD10/CTBP2/PRNP	5
GO:1902850	microtubule cytoskeleton organization involved in mitosis	10/896	147/18722	0.167276015916112	0.319650084230546	FLNA/RHOA/HSPA1A/SUN2/STAG2/HNRNPU/DYNLT1/CHMP1B/NUP62/ZNF207	10
GO:0002920	regulation of humoral immune response	4/896	45/18722	0.167292353254287	0.319650084230546	IL1B/PTPRC/PTPN6/TNF	4
GO:0042551	neuron maturation	4/896	45/18722	0.167292353254287	0.319650084230546	LRRK2/NR4A2/SCLT1/RB1	4
GO:0045933	positive regulation of muscle contraction	4/896	45/18722	0.167292353254287	0.319650084230546	RGS2/PTGS2/RHOA/PTAFR	4
GO:0051985	negative regulation of chromosome segregation	4/896	45/18722	0.167292353254287	0.319650084230546	DUSP1/ATM/ZNF207/DYNC1LI1	4
GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	4/896	45/18722	0.167292353254287	0.319650084230546	BID/HSPA1A/CHCHD10/BNIP3L	4
GO:1905819	negative regulation of chromosome separation	4/896	45/18722	0.167292353254287	0.319650084230546	DUSP1/ATM/ZNF207/DYNC1LI1	4
GO:0051054	positive regulation of DNA metabolic process	13/896	201/18722	0.167536107728902	0.319998272603019	PTPRC/KLF4/ACTR2/ARRB2/WAS/TGFB1/STAT6/PARP9/PTK2B/SMCHD1/DTX3L/MAPK1/ATM	13
GO:0010633	negative regulation of epithelial cell migration	8/896	112/18722	0.16814699331061	0.320929362278343	KLF4/MEF2C/TGFB1/TNF/RHOA/SP100/PTEN/CORO1C	8
GO:0035601	protein deacylation	8/896	112/18722	0.16814699331061	0.320929362278343	LRRK2/FLNA/PPT1/BCL6/NIPBL/MSL3/EP300/KDM5A	8
GO:0070588	calcium ion transmembrane transport	19/896	312/18722	0.168622885797214	0.321719599791383	CYBA/PTPRC/VMP1/CORO1A/CCL3/LYN/PTPN6/SLC8A1/KCNE3/FYN/PTK2B/FKBP1A/AHNAK/CALM2/G6PD/PRKACA/DIAPH1/MICU1/PRNP	19
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	6/896	78/18722	0.169679028765159	0.323615925415325	KLF4/PTGS2/RHOA/MAP3K3/HMOX1/CIB1	6
GO:1990823	response to leukemia inhibitory factor	7/896	95/18722	0.169749223540896	0.323631125966349	KLF4/SNX10/SOCS3/CTBP2/HNRNPU/CREB1/MAT2A	7
GO:0043467	regulation of generation of precursor metabolites and energy	9/896	130/18722	0.170869885039382	0.325457879432439	RHOA/FBP1/PRKAG2/STAT3/HIF1A/ZBTB7A/IRS2/EP300/IFNAR1	9
GO:0010948	negative regulation of cell cycle process	18/896	294/18722	0.170888130629206	0.325457879432439	DUSP1/ZFP36L2/KLF4/BCL6/ZFP36L1/TAOK3/CDKN1A/PRKAR1A/PTEN/RB1/ATM/NABP1/FOXN3/TAOK1/WAC/CTDSP1/ZNF207/DYNC1LI1	18
GO:0007176	regulation of epidermal growth factor-activated receptor activity	3/896	30/18722	0.171583446530234	0.325457879432439	NCF1/HBEGF/ADAM17	3
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	3/896	30/18722	0.171583446530234	0.325457879432439	SLC8A1/CALM2/PRKACA	3
GO:0031571	mitotic G1 DNA damage checkpoint signaling	3/896	30/18722	0.171583446530234	0.325457879432439	CDKN1A/ATM/WAC	3
GO:0034390	smooth muscle cell apoptotic process	3/896	30/18722	0.171583446530234	0.325457879432439	SOD2/ARRB2/STK4	3
GO:0034391	regulation of smooth muscle cell apoptotic process	3/896	30/18722	0.171583446530234	0.325457879432439	SOD2/ARRB2/STK4	3
GO:0036296	response to increased oxygen levels	3/896	30/18722	0.171583446530234	0.325457879432439	CDKN1A/ATP6V0D1/ATP6V1A	3
GO:0045070	positive regulation of viral genome replication	3/896	30/18722	0.171583446530234	0.325457879432439	PABPC1/ADAR/DDX3X	3
GO:0045948	positive regulation of translational initiation	3/896	30/18722	0.171583446530234	0.325457879432439	TNF/PPP1R15A/DDX3X	3
GO:0046825	regulation of protein export from nucleus	3/896	30/18722	0.171583446530234	0.325457879432439	IL1B/SP100/PRKACA	3
GO:0060292	long-term synaptic depression	3/896	30/18722	0.171583446530234	0.325457879432439	LILRB2/PTK2B/PTEN	3
GO:0140058	neuron projection arborization	3/896	30/18722	0.171583446530234	0.325457879432439	LRRK2/PHACTR1/ROCK1	3
GO:1900101	regulation of endoplasmic reticulum unfolded protein response	3/896	30/18722	0.171583446530234	0.325457879432439	PPP1R15A/PPP1R15B/PTPN2	3
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	5/896	62/18722	0.17466428740393	0.330622110277084	DUSP1/RB1/ATM/ZNF207/DYNC1LI1	5
GO:0009116	nucleoside metabolic process	5/896	62/18722	0.17466428740393	0.330622110277084	TYMP/APOBEC3A/DPYD/CDA/UPP1	5
GO:0048488	synaptic vesicle endocytosis	5/896	62/18722	0.17466428740393	0.330622110277084	LRRK2/ACTB/PICALM/ITSN2/ROCK1	5
GO:0140238	presynaptic endocytosis	5/896	62/18722	0.17466428740393	0.330622110277084	LRRK2/ACTB/PICALM/ITSN2/ROCK1	5
GO:0060541	respiratory system development	13/896	203/18722	0.176060243081747	0.330622110277084	KLF2/CTSH/CTSZ/TNF/EIF4EBP1/SMCHD1/CDC42/LIPA/MAPK1/TGFBR2/EP300/SP3/CREB1	13
GO:0003073	regulation of systemic arterial blood pressure	7/896	96/18722	0.176108436730526	0.330622110277084	CYBA/SOD2/CTSZ/RHOA/ATP6AP2/PRCP/WNK1	7
GO:0006637	acyl-CoA metabolic process	7/896	96/18722	0.176108436730526	0.330622110277084	PPT1/KYNU/ACSL1/PDK4/ELOVL5/ACSL4/FAR1	7
GO:0035383	thioester metabolic process	7/896	96/18722	0.176108436730526	0.330622110277084	PPT1/KYNU/ACSL1/PDK4/ELOVL5/ACSL4/FAR1	7
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	9/896	131/18722	0.176266027586324	0.330622110277084	SORL1/UBE2D1/HSPA1A/FKBP1A/SKIL/UBE2D3/ZBTB7A/ADAM17/FAM89B	9
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	2/896	16/18722	0.176736744978685	0.330622110277084	CTSZ/ATP6AP2	2
GO:0002566	somatic diversification of immune receptors via somatic mutation	2/896	16/18722	0.176736744978685	0.330622110277084	SAMHD1/ADAR	2
GO:0002693	positive regulation of cellular extravasation	2/896	16/18722	0.176736744978685	0.330622110277084	CCR2/PTAFR	2
GO:0002713	negative regulation of B cell mediated immunity	2/896	16/18722	0.176736744978685	0.330622110277084	PTPN6/BCL6	2
GO:0002890	negative regulation of immunoglobulin mediated immune response	2/896	16/18722	0.176736744978685	0.330622110277084	PTPN6/BCL6	2
GO:0005980	glycogen catabolic process	2/896	16/18722	0.176736744978685	0.330622110277084	PYGL/RB1CC1	2
GO:0006349	regulation of gene expression by genetic imprinting	2/896	16/18722	0.176736744978685	0.330622110277084	KDM1B/ARID4A	2
GO:0010649	regulation of cell communication by electrical coupling	2/896	16/18722	0.176736744978685	0.330622110277084	SLC8A1/CALM2	2
GO:0017014	protein nitrosylation	2/896	16/18722	0.176736744978685	0.330622110277084	S100A9/S100A8	2
GO:0018119	peptidyl-cysteine S-nitrosylation	2/896	16/18722	0.176736744978685	0.330622110277084	S100A9/S100A8	2
GO:0031268	pseudopodium organization	2/896	16/18722	0.176736744978685	0.330622110277084	CDC42EP3/CDC42	2
GO:0034393	positive regulation of smooth muscle cell apoptotic process	2/896	16/18722	0.176736744978685	0.330622110277084	SOD2/STK4	2
GO:0044804	autophagy of nucleus	2/896	16/18722	0.176736744978685	0.330622110277084	ATG3/RB1CC1	2
GO:0045838	positive regulation of membrane potential	2/896	16/18722	0.176736744978685	0.330622110277084	BID/GLRX	2
GO:0048311	mitochondrion distribution	2/896	16/18722	0.176736744978685	0.330622110277084	LRRK2/MEF2A	2
GO:0048385	regulation of retinoic acid receptor signaling pathway	2/896	16/18722	0.176736744978685	0.330622110277084	KLF2/CTBP2	2
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	2/896	16/18722	0.176736744978685	0.330622110277084	ARRB2/CXCR4	2
GO:0061684	chaperone-mediated autophagy	2/896	16/18722	0.176736744978685	0.330622110277084	CTSA/LAMP2	2
GO:0090231	regulation of spindle checkpoint	2/896	16/18722	0.176736744978685	0.330622110277084	DUSP1/DYNC1LI1	2
GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	2/896	16/18722	0.176736744978685	0.330622110277084	DUSP1/DYNC1LI1	2
GO:0097202	activation of cysteine-type endopeptidase activity	2/896	16/18722	0.176736744978685	0.330622110277084	PYCARD/IFI16	2
GO:0099633	protein localization to postsynaptic specialization membrane	2/896	16/18722	0.176736744978685	0.330622110277084	RAP1A/ADAM10	2
GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	2/896	16/18722	0.176736744978685	0.330622110277084	RAP1A/ADAM10	2
GO:1901163	regulation of trophoblast cell migration	2/896	16/18722	0.176736744978685	0.330622110277084	ARHGDIB/TIMP1	2
GO:1902931	negative regulation of alcohol biosynthetic process	2/896	16/18722	0.176736744978685	0.330622110277084	PLEK/NFKB1	2
GO:1903504	regulation of mitotic spindle checkpoint	2/896	16/18722	0.176736744978685	0.330622110277084	DUSP1/DYNC1LI1	2
GO:2001212	regulation of vasculogenesis	2/896	16/18722	0.176736744978685	0.330622110277084	RAP1A/RRAS	2
GO:0006984	ER-nucleus signaling pathway	4/896	46/18722	0.176785250659598	0.330622110277084	BID/PPP1R15A/PPP1R15B/PTPN2	4
GO:0031648	protein destabilization	4/896	46/18722	0.176785250659598	0.330622110277084	CTSH/PRNP/CREBBP/EP300	4
GO:0034198	cellular response to amino acid starvation	4/896	46/18722	0.176785250659598	0.330622110277084	UCP2/CDKN1A/MAPK1/ATF3	4
GO:0006631	fatty acid metabolic process	23/896	390/18722	0.177225624804587	0.331326554496282	IL1B/CD74/CD36/PTGS2/CYP1B1/AOAH/GPX1/HACD4/ALOX5/TBXAS1/LPGAT1/ACSL1/NAAA/PDK4/ALOX5AP/PRKAG2/ELOVL5/TNFRSF1A/ASAH1/ACSL4/DECR1/IRS2/QKI	23
GO:0032368	regulation of lipid transport	10/896	149/18722	0.177328583712609	0.33139991515964	IL1B/TSPO/NFKBIA/RETN/SYK/ACSL1/RXRA/LAMTOR1/IRS2/NFKB1	10
GO:0015931	nucleobase-containing compound transport	14/896	222/18722	0.178882494222429	0.334183855047002	ZFP36/NUP214/MX2/HHEX/ZFP36L1/SLC25A24/BICD2/YBX1/TGFBR2/NUP50/QKI/MVP/NUP62/SMG1	14
GO:0002244	hematopoietic progenitor cell differentiation	8/896	114/18722	0.179811546850755	0.335557895647929	PTPRC/SPI1/PLEK/PTPN6/TGFB1/CSF1R/ADAR/EEF2	8
GO:0021987	cerebral cortex development	8/896	114/18722	0.179811546850755	0.335557895647929	BCL2A1/FLNA/RHOA/PHACTR1/HIF1A/SUN2/MBOAT7/CELF1	8
GO:1903008	organelle disassembly	8/896	114/18722	0.179811546850755	0.335557895647929	TSPO/VPS13C/GABARAP/ATG3/BNIP3L/HIF1A/TOMM7/RB1CC1	8
GO:0022617	extracellular matrix disassembly	5/896	63/18722	0.182814566086345	0.340549786567418	CTSS/LCP1/CST3/TGFB1/ADAM10	5
GO:1902099	regulation of metaphase/anaphase transition of cell cycle	5/896	63/18722	0.182814566086345	0.340549786567418	DUSP1/RB1/ATM/ZNF207/DYNC1LI1	5
GO:2000242	negative regulation of reproductive process	5/896	63/18722	0.182814566086345	0.340549786567418	DUSP1/ARHGDIB/TIMP1/PRKAR1A/MYH9	5
GO:0002323	natural killer cell activation involved in immune response	3/896	31/18722	0.183665093505404	0.340549786567418	CORO1A/HLA-F/RAB27A	3
GO:0008045	motor neuron axon guidance	3/896	31/18722	0.183665093505404	0.340549786567418	RAC2/RHOG/MYCBP2	3
GO:0030149	sphingolipid catabolic process	3/896	31/18722	0.183665093505404	0.340549786567418	PPT1/ASAH1/NAGA	3
GO:0032509	endosome transport via multivesicular body sorting pathway	3/896	31/18722	0.183665093505404	0.340549786567418	LYST/TMEM50A/CHMP1B	3
GO:0036475	neuron death in response to oxidative stress	3/896	31/18722	0.183665093505404	0.340549786567418	MCL1/TLR4/HIF1A	3
GO:0044819	mitotic G1/S transition checkpoint signaling	3/896	31/18722	0.183665093505404	0.340549786567418	CDKN1A/ATM/WAC	3
GO:0045987	positive regulation of smooth muscle contraction	3/896	31/18722	0.183665093505404	0.340549786567418	PTGS2/RHOA/PTAFR	3
GO:0048384	retinoic acid receptor signaling pathway	3/896	31/18722	0.183665093505404	0.340549786567418	KLF2/RXRA/CTBP2	3
GO:0048566	embryonic digestive tract development	3/896	31/18722	0.183665093505404	0.340549786567418	CXCL8/TNF/NIPBL	3
GO:0060390	regulation of SMAD protein signal transduction	3/896	31/18722	0.183665093505404	0.340549786567418	JAK2/TGFB1/FAM89B	3
GO:0070723	response to cholesterol	3/896	31/18722	0.183665093505404	0.340549786567418	CCL3/TGFB1/TGFBR2	3
GO:0071168	protein localization to chromatin	3/896	31/18722	0.183665093505404	0.340549786567418	SPI1/RB1/NIPBL	3
GO:1900027	regulation of ruffle assembly	3/896	31/18722	0.183665093505404	0.340549786567418	RHOG/PFN1/CORO1C	3
GO:1901797	negative regulation of signal transduction by p53 class mediator	3/896	31/18722	0.183665093505404	0.340549786567418	CD74/CD44/ZNF385A	3
GO:2000144	positive regulation of DNA-templated transcription, initiation	3/896	31/18722	0.183665093505404	0.340549786567418	JUN/SETX/CREB1	3
GO:0061136	regulation of proteasomal protein catabolic process	12/896	187/18722	0.186215463059507	0.34474034874587	LRRK2/GPX1/HSPA1A/PSME2/TRIB1/PSME1/GABARAP/PRKACA/SDCBP/PIAS1/WAC/HERPUD1	12
GO:0007595	lactation	4/896	47/18722	0.186455412617215	0.34474034874587	OAS2/HIF1A/USF2/CREB1	4
GO:0009261	ribonucleotide catabolic process	4/896	47/18722	0.186455412617215	0.34474034874587	DPYD/UPP1/NUDT16/NUDT3	4
GO:0014911	positive regulation of smooth muscle cell migration	4/896	47/18722	0.186455412617215	0.34474034874587	AIF1/IQGAP1/TLR4/PAK1	4
GO:0032008	positive regulation of TOR signaling	4/896	47/18722	0.186455412617215	0.34474034874587	NCKAP1L/LAMTOR4/LAMTOR1/WAC	4
GO:0035850	epithelial cell differentiation involved in kidney development	4/896	47/18722	0.186455412617215	0.34474034874587	STAT1/MEF2C/IQGAP1/NOTCH2	4
GO:0051489	regulation of filopodium assembly	4/896	47/18722	0.186455412617215	0.34474034874587	DOCK11/ARAP1/RHOQ/CDC42	4
GO:0072583	clathrin-dependent endocytosis	4/896	47/18722	0.186455412617215	0.34474034874587	ITGA4/PICALM/ITSN2/BMP2K	4
GO:0009152	purine ribonucleotide biosynthetic process	11/896	169/18722	0.187221549041802	0.346033858054873	TMSB4X/PPT1/TGFB1/ACSL1/PDK4/PRKAG2/ELOVL5/ATP6V1A/STAT3/ADCY7/ACSL4	11
GO:0046888	negative regulation of hormone secretion	5/896	64/18722	0.191101830152704	0.352848469546977	IL1B/UCP2/MIDN/RAB11FIP1/PPP3CA	5
GO:0021954	central nervous system neuron development	6/896	81/18722	0.191247805355302	0.352848469546977	BTG2/NR4A2/AGTPBP1/NIN/PTEN/MYCBP2	6
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	6/896	81/18722	0.191247805355302	0.352848469546977	HSPA1A/FKBP1A/SKIL/ZBTB7A/ADAM17/FAM89B	6
GO:0044773	mitotic DNA damage checkpoint signaling	6/896	81/18722	0.191247805355302	0.352848469546977	TAOK3/CDKN1A/ATM/FOXN3/TAOK1/WAC	6
GO:2001021	negative regulation of response to DNA damage stimulus	6/896	81/18722	0.191247805355302	0.352848469546977	CD74/CD44/BID/SMCHD1/ZNF385A/TRIP12	6
GO:0098732	macromolecule deacylation	8/896	116/18722	0.191818664159898	0.353776195849515	LRRK2/FLNA/PPT1/BCL6/NIPBL/MSL3/EP300/KDM5A	8
GO:0061041	regulation of wound healing	9/896	134/18722	0.192908374677808	0.354958774206214	CLEC7A/CD36/TNFAIP3/HBEGF/CXCR4/TNF/ALOX5/SH2B3/PTEN	9
GO:0001780	neutrophil homeostasis	2/896	17/18722	0.194302563000402	0.354958774206214	CCR2/SH2B3	2
GO:0001829	trophectodermal cell differentiation	2/896	17/18722	0.194302563000402	0.354958774206214	JUNB/SP3	2
GO:0006474	N-terminal protein amino acid acetylation	2/896	17/18722	0.194302563000402	0.354958774206214	CREBBP/EP300	2
GO:0008340	determination of adult lifespan	2/896	17/18722	0.194302563000402	0.354958774206214	LRRK2/INPP5D	2
GO:0009151	purine deoxyribonucleotide metabolic process	2/896	17/18722	0.194302563000402	0.354958774206214	SAMHD1/NUDT16	2
GO:0009200	deoxyribonucleoside triphosphate metabolic process	2/896	17/18722	0.194302563000402	0.354958774206214	SAMHD1/NUDT16	2
GO:0009251	glucan catabolic process	2/896	17/18722	0.194302563000402	0.354958774206214	PYGL/RB1CC1	2
GO:0010224	response to UV-B	2/896	17/18722	0.194302563000402	0.354958774206214	CRIP1/CDKN1A	2
GO:0010715	regulation of extracellular matrix disassembly	2/896	17/18722	0.194302563000402	0.354958774206214	CST3/TGFB1	2
GO:0020027	hemoglobin metabolic process	2/896	17/18722	0.194302563000402	0.354958774206214	KLF4/HIF1A	2
GO:0021756	striatum development	2/896	17/18722	0.194302563000402	0.354958774206214	LRRK2/ZSWIM6	2
GO:0030002	cellular anion homeostasis	2/896	17/18722	0.194302563000402	0.354958774206214	KCNE3/TBXAS1	2
GO:0033623	regulation of integrin activation	2/896	17/18722	0.194302563000402	0.354958774206214	PLEK/RAP1B	2
GO:0034349	glial cell apoptotic process	2/896	17/18722	0.194302563000402	0.354958774206214	BID/RB1	2
GO:0043968	histone H2A acetylation	2/896	17/18722	0.194302563000402	0.354958774206214	MSL3/EPC1	2
GO:0045815	positive regulation of gene expression, epigenetic	2/896	17/18722	0.194302563000402	0.354958774206214	ARID1A/EP300	2
GO:0046827	positive regulation of protein export from nucleus	2/896	17/18722	0.194302563000402	0.354958774206214	IL1B/PRKACA	2
GO:0055064	chloride ion homeostasis	2/896	17/18722	0.194302563000402	0.354958774206214	KCNE3/TBXAS1	2
GO:0055083	monovalent inorganic anion homeostasis	2/896	17/18722	0.194302563000402	0.354958774206214	KCNE3/TBXAS1	2
GO:0055119	relaxation of cardiac muscle	2/896	17/18722	0.194302563000402	0.354958774206214	RGS2/SLC8A1	2
GO:0060644	mammary gland epithelial cell differentiation	2/896	17/18722	0.194302563000402	0.354958774206214	CEBPB/HIF1A	2
GO:0061298	retina vasculature development in camera-type eye	2/896	17/18722	0.194302563000402	0.354958774206214	CYP1B1/HIF1A	2
GO:0061450	trophoblast cell migration	2/896	17/18722	0.194302563000402	0.354958774206214	ARHGDIB/TIMP1	2
GO:0070206	protein trimerization	2/896	17/18722	0.194302563000402	0.354958774206214	CD74/ALOX5AP	2
GO:0090083	regulation of inclusion body assembly	2/896	17/18722	0.194302563000402	0.354958774206214	SORL1/HSPA1A	2
GO:0090399	replicative senescence	2/896	17/18722	0.194302563000402	0.354958774206214	CDKN1A/ATM	2
GO:0003018	vascular process in circulatory system	16/896	263/18722	0.194672476746899	0.355509674003027	RGS2/SLC2A3/SOD2/KLF2/CD36/PTGS2/GPX1/TGFB1/SLC8A1/SCPEP1/RHOA/TBXAS1/SLCO3A1/GCH1/ROCK1/PLEC	16
GO:0051153	regulation of striated muscle cell differentiation	7/896	99/18722	0.195775377053158	0.356738945634985	RGS2/ARRB2/MEF2C/TGFB1/G6PD/PAK1/YBX1	7
GO:0003180	aortic valve morphogenesis	3/896	32/18722	0.195962923991377	0.356738945634985	TGFB1/ROCK1/RB1	3
GO:0007435	salivary gland morphogenesis	3/896	32/18722	0.195962923991377	0.356738945634985	TGFB1/TNF/CDC42	3
GO:0010644	cell communication by electrical coupling	3/896	32/18722	0.195962923991377	0.356738945634985	SLC8A1/CALM2/PRKACA	3
GO:0010743	regulation of macrophage derived foam cell differentiation	3/896	32/18722	0.195962923991377	0.356738945634985	NFKBIA/CD36/NFKB1	3
GO:0019835	cytolysis	3/896	32/18722	0.195962923991377	0.356738945634985	LYZ/TGFB1/NINJ1	3
GO:0051642	centrosome localization	3/896	32/18722	0.195962923991377	0.356738945634985	NIN/SUN2/BICD2	3
GO:0071875	adrenergic receptor signaling pathway	3/896	32/18722	0.195962923991377	0.356738945634985	RGS2/GNAI2/AKAP13	3
GO:1903955	positive regulation of protein targeting to mitochondrion	3/896	32/18722	0.195962923991377	0.356738945634985	RAC2/UBE2D3/TOMM7	3
GO:0002686	negative regulation of leukocyte migration	4/896	48/18722	0.19629152194463	0.356962309662245	DUSP1/RIN3/CD300A/HMOX1	4
GO:0045839	negative regulation of mitotic nuclear division	4/896	48/18722	0.19629152194463	0.356962309662245	DUSP1/ATM/ZNF207/DYNC1LI1	4
GO:0048146	positive regulation of fibroblast proliferation	4/896	48/18722	0.19629152194463	0.356962309662245	CD74/S100A6/CDKN1A/FOSL2	4
GO:0051225	spindle assembly	8/896	117/18722	0.197945128475156	0.359843625725022	FLNA/RHOA/HSPA1A/CCDC69/STAG2/HNRNPU/CHMP1B/ZNF207	8
GO:0007032	endosome organization	6/896	82/18722	0.198660876254213	0.36089249647159	SNX10/RAB27A/CORO1C/LAMTOR1/CHMP1B/HOOK3	6
GO:0060395	SMAD protein signal transduction	6/896	82/18722	0.198660876254213	0.36089249647159	FOS/VIM/JAK2/TGFB1/JUN/FAM89B	6
GO:0010965	regulation of mitotic sister chromatid separation	5/896	65/18722	0.199519442367919	0.362199169199143	DUSP1/RB1/ATM/ZNF207/DYNC1LI1	5
GO:0044784	metaphase/anaphase transition of cell cycle	5/896	65/18722	0.199519442367919	0.362199169199143	DUSP1/RB1/ATM/ZNF207/DYNC1LI1	5
GO:1990138	neuron projection extension	11/896	172/18722	0.202254252851895	0.367035718451747	ITGA4/IQGAP1/CXCR4/ARHGAP4/DPYSL2/C9orf72/SHTN1/PAK1/TWF2/ITSN2/DBNL	11
GO:0006626	protein targeting to mitochondrion	7/896	100/18722	0.202517368565991	0.367256915589861	TSPO/LRRK2/RAC2/BID/BNIP3L/UBE2D3/TOMM7	7
GO:0006641	triglyceride metabolic process	7/896	100/18722	0.202517368565991	0.367256915589861	GPX1/SORL1/LPGAT1/APOBR/ACSL1/ACSL4/MBOAT7	7
GO:0051168	nuclear export	10/896	154/18722	0.203633240264662	0.369151788991463	IL1B/NUP214/TGFB1/HHEX/AKAP13/SP100/CHP1/PRKACA/NUP62/SMG1	10
GO:0060070	canonical Wnt signaling pathway	18/896	303/18722	0.203843952585594	0.36940501651487	ZEB2/LRRK2/EGR1/KLF4/NR4A2/TGFB1/SULF2/PFDN5/HHEX/STK4/GNAQ/CCNY/PTEN/CYLD/ATP6AP2/DDX3X/WNK1/NFKB1	18
GO:0006413	translational initiation	8/896	118/18722	0.204150440091286	0.369702799065034	TNF/EIF1/EIF4EBP1/PPP1R15A/EIF2S3/PPP1R15B/EIF3K/DDX3X	8
GO:0030203	glycosaminoglycan metabolic process	8/896	118/18722	0.204150440091286	0.369702799065034	IL1B/CD44/TGFB1/CSGALNACT2/GNS/IDS/DSE/NFKB1	8
GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	4/896	49/18722	0.206282208235593	0.37265500695843	PTPRC/TGFB1/STAT6/BCL6	4
GO:0002208	somatic diversification of immunoglobulins involved in immune response	4/896	49/18722	0.206282208235593	0.37265500695843	PTPRC/TGFB1/STAT6/BCL6	4
GO:0006778	porphyrin-containing compound metabolic process	4/896	49/18722	0.206282208235593	0.37265500695843	TSPO/BLVRB/BLVRA/HMOX1	4
GO:0010823	negative regulation of mitochondrion organization	4/896	49/18722	0.206282208235593	0.37265500695843	TSPO/ARRB2/GPX1/HSPA1A	4
GO:0045190	isotype switching	4/896	49/18722	0.206282208235593	0.37265500695843	PTPRC/TGFB1/STAT6/BCL6	4
GO:0046580	negative regulation of Ras protein signal transduction	4/896	49/18722	0.206282208235593	0.37265500695843	BCL6/FBP1/TIMP2/NUP62	4
GO:0060986	endocrine hormone secretion	4/896	49/18722	0.206282208235593	0.37265500695843	IL1B/RETN/RAB8B/RAB11FIP1	4
GO:0010469	regulation of signaling receptor activity	11/896	173/18722	0.20737901935863	0.374506347112582	NCF1/MEF2C/IFNGR2/JAK2/CCR2/HBEGF/TNF/PTK2B/PTEN/HIF1A/ADAM17	11
GO:0006303	double-strand break repair via nonhomologous end joining	5/896	66/18722	0.208060669727761	0.374885369020663	PARP9/SMCHD1/DTX3L/ATM/ZBTB7A	5
GO:0042446	hormone biosynthetic process	5/896	66/18722	0.208060669727761	0.374885369020663	TSPO/EGR1/HSD17B11/HIF1A/NFKB1	5
GO:2000573	positive regulation of DNA biosynthetic process	5/896	66/18722	0.208060669727761	0.374885369020663	KLF4/ARRB2/PTK2B/MAPK1/ATM	5
GO:0001881	receptor recycling	3/896	33/18722	0.208453852568305	0.374885369020663	SORL1/ARAP1/LAMTOR1	3
GO:0010165	response to X-ray	3/896	33/18722	0.208453852568305	0.374885369020663	CDKN1A/NIPBL/ATM	3
GO:0010259	multicellular organism aging	3/896	33/18722	0.208453852568305	0.374885369020663	LRRK2/INPP5D/SERP1	3
GO:0031116	positive regulation of microtubule polymerization	3/896	33/18722	0.208453852568305	0.374885369020663	HSPA1A/NIN/PAK1	3
GO:0046320	regulation of fatty acid oxidation	3/896	33/18722	0.208453852568305	0.374885369020663	PDK4/PRKAG2/IRS2	3
GO:0150117	positive regulation of cell-substrate junction organization	3/896	33/18722	0.208453852568305	0.374885369020663	IQGAP1/ROCK1/LIMS1	3
GO:1901380	negative regulation of potassium ion transmembrane transport	3/896	33/18722	0.208453852568305	0.374885369020663	KCNE3/PTEN/CAB39	3
GO:1902692	regulation of neuroblast proliferation	3/896	33/18722	0.208453852568305	0.374885369020663	LRRK2/CX3CR1/HIF1A	3
GO:1904031	positive regulation of cyclin-dependent protein kinase activity	3/896	33/18722	0.208453852568305	0.374885369020663	CDKN1A/CCNY/ADAM17	3
GO:0046434	organophosphate catabolic process	10/896	155/18722	0.209084162724238	0.375888949301334	TYMP/SAMHD1/DPYD/GPCPD1/UPP1/ENTPD1/NUDT16/PLBD1/PTEN/NUDT3	10
GO:0006476	protein deacetylation	7/896	101/18722	0.209347298361741	0.376102003032613	LRRK2/FLNA/BCL6/NIPBL/MSL3/EP300/KDM5A	7
GO:0048024	regulation of mRNA splicing, via spliceosome	7/896	101/18722	0.209347298361741	0.376102003032613	MBNL1/CELF2/DDX5/ZBTB7A/HNRNPU/QKI/CELF1	7
GO:0000086	G2/M transition of mitotic cell cycle	9/896	137/18722	0.210195144250403	0.377351356600723	BACH1/CALM2/TAOK3/CDKN1A/CCNY/ATM/NABP1/FOXN3/TAOK1	9
GO:0006957	complement activation, alternative pathway	2/896	18/18722	0.212074219447013	0.377351356600723	CFD/CFP	2
GO:0010663	positive regulation of striated muscle cell apoptotic process	2/896	18/18722	0.212074219447013	0.377351356600723	CAPN2/PTEN	2
GO:0010666	positive regulation of cardiac muscle cell apoptotic process	2/896	18/18722	0.212074219447013	0.377351356600723	CAPN2/PTEN	2
GO:0015732	prostaglandin transport	2/896	18/18722	0.212074219447013	0.377351356600723	IL1B/SLCO3A1	2
GO:0019896	axonal transport of mitochondrion	2/896	18/18722	0.212074219447013	0.377351356600723	AGTPBP1/HIF1A	2
GO:0030206	chondroitin sulfate biosynthetic process	2/896	18/18722	0.212074219447013	0.377351356600723	CSGALNACT2/DSE	2
GO:0030728	ovulation	2/896	18/18722	0.212074219447013	0.377351356600723	RGS2/PTGS2	2
GO:0034162	toll-like receptor 9 signaling pathway	2/896	18/18722	0.212074219447013	0.377351356600723	PIK3AP1/UNC93B1	2
GO:0035372	protein localization to microtubule	2/896	18/18722	0.212074219447013	0.377351356600723	DIAPH1/HNRNPU	2
GO:0035743	CD4-positive, alpha-beta T cell cytokine production	2/896	18/18722	0.212074219447013	0.377351356600723	IL1B/NLRP3	2
GO:0051447	negative regulation of meiotic cell cycle	2/896	18/18722	0.212074219447013	0.377351356600723	DUSP1/PRKAR1A	2
GO:0060008	Sertoli cell differentiation	2/896	18/18722	0.212074219447013	0.377351356600723	FLNA/ARID4A	2
GO:0060391	positive regulation of SMAD protein signal transduction	2/896	18/18722	0.212074219447013	0.377351356600723	JAK2/TGFB1	2
GO:0060438	trachea development	2/896	18/18722	0.212074219447013	0.377351356600723	MAPK1/TGFBR2	2
GO:0060546	negative regulation of necroptotic process	2/896	18/18722	0.212074219447013	0.377351356600723	BIRC3/BIRC2	2
GO:0060716	labyrinthine layer blood vessel development	2/896	18/18722	0.212074219447013	0.377351356600723	JUNB/MAPK1	2
GO:0061484	hematopoietic stem cell homeostasis	2/896	18/18722	0.212074219447013	0.377351356600723	TCIRG1/ADAR	2
GO:0071071	regulation of phospholipid biosynthetic process	2/896	18/18722	0.212074219447013	0.377351356600723	CAPN2/CHP1	2
GO:0071360	cellular response to exogenous dsRNA	2/896	18/18722	0.212074219447013	0.377351356600723	RALB/IFIH1	2
GO:0071786	endoplasmic reticulum tubular network organization	2/896	18/18722	0.212074219447013	0.377351356600723	RTN3/RAB10	2
GO:0099558	maintenance of synapse structure	2/896	18/18722	0.212074219447013	0.377351356600723	CHCHD10/CTBP2	2
GO:1900242	regulation of synaptic vesicle endocytosis	2/896	18/18722	0.212074219447013	0.377351356600723	LRRK2/ROCK1	2
GO:1900424	regulation of defense response to bacterium	2/896	18/18722	0.212074219447013	0.377351356600723	CYBA/GRN	2
GO:1902170	cellular response to reactive nitrogen species	2/896	18/18722	0.212074219447013	0.377351356600723	STAT6/CFLAR	2
GO:1903209	positive regulation of oxidative stress-induced cell death	2/896	18/18722	0.212074219447013	0.377351356600723	MCL1/TLR4	2
GO:1905820	positive regulation of chromosome separation	2/896	18/18722	0.212074219447013	0.377351356600723	PLSCR1/RB1	2
GO:2000641	regulation of early endosome to late endosome transport	2/896	18/18722	0.212074219447013	0.377351356600723	MSN/MAPK1	2
GO:0001764	neuron migration	10/896	156/18722	0.214594953632987	0.381706003367019	FLNA/MEF2C/NR4A2/CXCR4/PHACTR1/FYN/SHTN1/STAT3/PLXNB2/NIPBL	10
GO:0001935	endothelial cell proliferation	12/896	193/18722	0.215094889552345	0.382464451474101	CYBA/STAT1/NR4A1/MEF2C/ITGA4/TNF/ALOX5/STAT3/HIF1A/HMOX1/SP1/ADAM17	12
GO:0060562	epithelial tube morphogenesis	19/896	325/18722	0.215260098023676	0.38262739911864	RHOB/MEF2C/VASP/CTSH/TGFB1/NOTCH2/CTSZ/CSF1R/CXCR4/TNF/RHOA/ITGAX/STK4/PAK1/PRKACA/PFN1/HIF1A/PLXNB2/TGFBR2	19
GO:0001841	neural tube formation	7/896	102/18722	0.216261924931608	0.383247569031381	VASP/TGFB1/STK4/PRKACA/PFN1/HIF1A/PLXNB2	7
GO:0010665	regulation of cardiac muscle cell apoptotic process	4/896	50/18722	0.216416085857131	0.383247569031381	JAK2/CAPN2/CFLAR/PTEN	4
GO:0018023	peptidyl-lysine trimethylation	4/896	50/18722	0.216416085857131	0.383247569031381	KMT2E/ARID4A/TET2/KMT2A	4
GO:0038202	TORC1 signaling	4/896	50/18722	0.216416085857131	0.383247569031381	C9orf72/ATM/WAC/SMG1	4
GO:0045814	negative regulation of gene expression, epigenetic	4/896	50/18722	0.216416085857131	0.383247569031381	SPI1/SMCHD1/MBD2/EPC1	4
GO:0051646	mitochondrion localization	4/896	50/18722	0.216416085857131	0.383247569031381	LRRK2/AGTPBP1/MEF2A/HIF1A	4
GO:1902930	regulation of alcohol biosynthetic process	4/896	50/18722	0.216416085857131	0.383247569031381	PLEK/PTAFR/PTK2B/NFKB1	4
GO:1904036	negative regulation of epithelial cell apoptotic process	4/896	50/18722	0.216416085857131	0.383247569031381	TNFAIP3/CFLAR/CAST/HMOX1	4
GO:0006513	protein monoubiquitination	5/896	67/18722	0.216718702140703	0.383247569031381	DTX3L/UBE2D3/UBE2R2/WAC/BIRC2	5
GO:0016445	somatic diversification of immunoglobulins	5/896	67/18722	0.216718702140703	0.383247569031381	PTPRC/SAMHD1/TGFB1/STAT6/BCL6	5
GO:0032890	regulation of organic acid transport	5/896	67/18722	0.216718702140703	0.383247569031381	IL1B/RGS2/SYK/ACSL1/IRS2	5
GO:0043967	histone H4 acetylation	5/896	67/18722	0.216718702140703	0.383247569031381	SPI1/MSL3/EP300/KMT2A/EPC1	5
GO:0051306	mitotic sister chromatid separation	5/896	67/18722	0.216718702140703	0.383247569031381	DUSP1/RB1/ATM/ZNF207/DYNC1LI1	5
GO:0061077	chaperone-mediated protein folding	5/896	67/18722	0.216718702140703	0.383247569031381	CD74/FKBP5/HSPA1A/FKBP1A/CRTAP	5
GO:0006304	DNA modification	8/896	120/18722	0.216787992326538	0.383247569031381	FOS/APOBEC3A/SPI1/KDM1B/KMT2E/TET2/MBD2/KMT2A	8
GO:0072655	establishment of protein localization to mitochondrion	8/896	120/18722	0.216787992326538	0.383247569031381	TSPO/LRRK2/RAC2/BID/BNIP3L/UBE2D3/TOMM7/OXA1L	8
GO:0006644	phospholipid metabolic process	22/896	383/18722	0.217205713204023	0.383855560439729	PLEK/SOCS3/GPCPD1/PLSCR1/CSF1R/LPGAT1/LPCAT2/PLCB2/INPP5D/SPTLC2/OSBPL8/CAPN2/NAAA/PLBD1/CHP1/PTEN/DGKZ/MBOAT7/ATM/PIP4K2A/FAR1/SMG1	22
GO:1903311	regulation of mRNA metabolic process	17/896	288/18722	0.219507361803462	0.387791368457814	ZFP36/VIM/ZFP36L2/SLC11A1/BTG2/PABPC1/MBNL1/CELF2/MYD88/ZFP36L1/DDX5/ROCK1/ZBTB7A/YBX1/HNRNPU/QKI/CELF1	17
GO:1902600	proton transmembrane transport	10/896	157/18722	0.220164054853637	0.388819439488545	TMSB4X/UCP2/TCIRG1/HVCN1/ATP6V1B2/CHP1/ATP6V0D1/ATP6V1A/ATP6V0B/ATP6V1F	10
GO:0000038	very long-chain fatty acid metabolic process	3/896	34/18722	0.221115298482696	0.389573396818598	HACD4/ACSL1/ELOVL5	3
GO:0007431	salivary gland development	3/896	34/18722	0.221115298482696	0.389573396818598	TGFB1/TNF/CDC42	3
GO:0007616	long-term memory	3/896	34/18722	0.221115298482696	0.389573396818598	SGK1/PJA2/PRNP	3
GO:0016242	negative regulation of macroautophagy	3/896	34/18722	0.221115298482696	0.389573396818598	LRRK2/HMOX1/SMG1	3
GO:0035590	purinergic nucleotide receptor signaling pathway	3/896	34/18722	0.221115298482696	0.389573396818598	GNAI2/P2RY13/PTAFR	3
GO:0043276	anoikis	3/896	34/18722	0.221115298482696	0.389573396818598	MCL1/PDK4/ITGA5	3
GO:0048741	skeletal muscle fiber development	3/896	34/18722	0.221115298482696	0.389573396818598	GPX1/PPP3CA/PLEC	3
GO:0044774	mitotic DNA integrity checkpoint signaling	6/896	85/18722	0.221508589445744	0.390002089948312	TAOK3/CDKN1A/ATM/FOXN3/TAOK1/WAC	6
GO:2000779	regulation of double-strand break repair	6/896	85/18722	0.221508589445744	0.390002089948312	ACTR2/WAS/PARP9/SMCHD1/DTX3L/TRIP12	6
GO:0030216	keratinocyte differentiation	9/896	139/18722	0.222053049390622	0.390828395898688	TXNIP/ZFP36/CSTA/ZFP36L1/STK4/ROCK1/FOSL2/ASAH1/PLEC	9
GO:0007585	respiratory gaseous exchange by respiratory system	5/896	68/18722	0.225486670455503	0.39633530687363	MAFB/NR4A2/CSF2RB/ZFAND5/HNMT	5
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	5/896	68/18722	0.225486670455503	0.39633530687363	TMSB4X/TGFB1/PRKAG2/ATP6V1A/STAT3	5
GO:0034394	protein localization to cell surface	5/896	68/18722	0.225486670455503	0.39633530687363	FCN1/TYROBP/FLNA/TNF/PICALM	5
GO:0061912	selective autophagy	5/896	68/18722	0.225486670455503	0.39633530687363	VPS13C/SPTLC2/TOMM7/CALCOCO2/RB1CC1	5
GO:0032964	collagen biosynthetic process	4/896	51/18722	0.22668178943143	0.398166831081684	VIM/ARRB2/TGFB1/RAP1A	4
GO:0060043	regulation of cardiac muscle cell proliferation	4/896	51/18722	0.22668178943143	0.398166831081684	MEF2C/PTEN/MAPK1/TGFBR2	4
GO:0030111	regulation of Wnt signaling pathway	19/896	328/18722	0.226796695632942	0.398234170826109	ZEB2/LRRK2/EGR1/TNFAIP3/RNF213/TLR2/TGFB1/SULF2/PFDN5/HHEX/STK4/GNAQ/CCNY/CYLD/ATP6AP2/MBD2/DDX3X/WNK1/NFKB1	19
GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	14/896	233/18722	0.22735455255629	0.398596362878433	RGS2/FPR1/FLNA/GNAI2/ADGRE5/PSAP/ADGRE2/GPR65/AKAP13/GNAQ/ADCY7/GNB1/GNAI3/GNA13	14
GO:0045017	glycerolipid biosynthetic process	15/896	252/18722	0.227796373657398	0.398596362878433	SOCS3/PLSCR1/LPGAT1/LPCAT2/INPP5D/ACSL1/CAPN2/PTEN/DGKZ/ACSL4/MBOAT7/ATM/PIP4K2A/FAR1/SMG1	15
GO:0061448	connective tissue development	15/896	252/18722	0.227796373657398	0.398596362878433	CRIP1/CD44/TIMP1/SPI1/EGR1/MEF2C/TGFBI/TGFB1/SORL1/SULF2/IL6R/SPTLC2/CFLAR/HIF1A/TGFBR2	15
GO:0015908	fatty acid transport	6/896	86/18722	0.229312076088491	0.398596362878433	IL1B/CD36/SYK/ACSL1/ACSL4/IRS2	6
GO:0046928	regulation of neurotransmitter secretion	6/896	86/18722	0.229312076088491	0.398596362878433	LRRK2/MEF2C/PRKCB/MCTP1/RAP1A/RAP1B	6
GO:2001251	negative regulation of chromosome organization	6/896	86/18722	0.229312076088491	0.398596362878433	DUSP1/ATM/HNRNPU/XRN1/ZNF207/DYNC1LI1	6
GO:0019730	antimicrobial humoral response	8/896	122/18722	0.229711584187628	0.398596362878433	LYZ/S100A9/S100A12/HLA-A/SLC11A1/HLA-E/CXCL8/RNASE6	8
GO:0001696	gastric acid secretion	2/896	19/18722	0.229991864064252	0.398596362878433	SNX10/SGK1	2
GO:0003085	negative regulation of systemic arterial blood pressure	2/896	19/18722	0.229991864064252	0.398596362878433	SOD2/PRCP	2
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2/896	19/18722	0.229991864064252	0.398596362878433	CDKN1A/ATM	2
GO:0010738	regulation of protein kinase A signaling	2/896	19/18722	0.229991864064252	0.398596362878433	LRRK2/PJA2	2
GO:0010744	positive regulation of macrophage derived foam cell differentiation	2/896	19/18722	0.229991864064252	0.398596362878433	CD36/NFKB1	2
GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling	2/896	19/18722	0.229991864064252	0.398596362878433	KLF4/PTEN	2
GO:0015802	basic amino acid transport	2/896	19/18722	0.229991864064252	0.398596362878433	SLC11A1/SLC7A7	2
GO:0030011	maintenance of cell polarity	2/896	19/18722	0.229991864064252	0.398596362878433	NCKAP1L/ARPC5	2
GO:0030050	vesicle transport along actin filament	2/896	19/18722	0.229991864064252	0.398596362878433	MYO1F/MYO1G	2
GO:0032011	ARF protein signal transduction	2/896	19/18722	0.229991864064252	0.398596362878433	CYTH4/CYTH1	2
GO:0032012	regulation of ARF protein signal transduction	2/896	19/18722	0.229991864064252	0.398596362878433	CYTH4/CYTH1	2
GO:0032026	response to magnesium ion	2/896	19/18722	0.229991864064252	0.398596362878433	CD14/FBP1	2
GO:0043031	negative regulation of macrophage activation	2/896	19/18722	0.229991864064252	0.398596362878433	PTPRC/GRN	2
GO:0043652	engulfment of apoptotic cell	2/896	19/18722	0.229991864064252	0.398596362878433	RAC2/RHOG	2
GO:0044003	modulation by symbiont of host process	2/896	19/18722	0.229991864064252	0.398596362878433	CD4/RXRA	2
GO:0044320	cellular response to leptin stimulus	2/896	19/18722	0.229991864064252	0.398596362878433	STAT3/PTEN	2
GO:0045019	negative regulation of nitric oxide biosynthetic process	2/896	19/18722	0.229991864064252	0.398596362878433	TSPO/SIRPA	2
GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate	2/896	19/18722	0.229991864064252	0.398596362878433	APOBEC3A/CXCL8	2
GO:0046653	tetrahydrofolate metabolic process	2/896	19/18722	0.229991864064252	0.398596362878433	GCH1/MTHFD2	2
GO:0046782	regulation of viral transcription	2/896	19/18722	0.229991864064252	0.398596362878433	ZFP36/IFITM3	2
GO:0046794	transport of virus	2/896	19/18722	0.229991864064252	0.398596362878433	BST2/DYNLT1	2
GO:0048245	eosinophil chemotaxis	2/896	19/18722	0.229991864064252	0.398596362878433	CCL3/CCL4	2
GO:0048490	anterograde synaptic vesicle transport	2/896	19/18722	0.229991864064252	0.398596362878433	BLOC1S1/BLOC1S6	2
GO:0050961	detection of temperature stimulus involved in sensory perception	2/896	19/18722	0.229991864064252	0.398596362878433	ARRB2/CXCR4	2
GO:0051546	keratinocyte migration	2/896	19/18722	0.229991864064252	0.398596362878433	HBEGF/PTEN	2
GO:0051571	positive regulation of histone H3-K4 methylation	2/896	19/18722	0.229991864064252	0.398596362878433	KMT2E/KMT2A	2
GO:0062099	negative regulation of programmed necrotic cell death	2/896	19/18722	0.229991864064252	0.398596362878433	BIRC3/BIRC2	2
GO:0071545	inositol phosphate catabolic process	2/896	19/18722	0.229991864064252	0.398596362878433	PTEN/NUDT3	2
GO:0098780	response to mitochondrial depolarisation	2/896	19/18722	0.229991864064252	0.398596362878433	VPS13C/TOMM7	2
GO:0099514	synaptic vesicle cytoskeletal transport	2/896	19/18722	0.229991864064252	0.398596362878433	BLOC1S1/BLOC1S6	2
GO:0099517	synaptic vesicle transport along microtubule	2/896	19/18722	0.229991864064252	0.398596362878433	BLOC1S1/BLOC1S6	2
GO:1904406	negative regulation of nitric oxide metabolic process	2/896	19/18722	0.229991864064252	0.398596362878433	TSPO/SIRPA	2
GO:0032006	regulation of TOR signaling	7/896	104/18722	0.230332013658598	0.399052899080069	NCKAP1L/LAMTOR4/C9orf72/HIF1A/ATM/LAMTOR1/WAC	7
GO:0035966	response to topologically incorrect protein	10/896	159/18722	0.231470787842778	0.400892296893204	SERP1/HSPA1A/PPP1R15A/PPP1R15B/CREBRF/ATF3/PTPN2/TMBIM6/EP300/HERPUD1	10
GO:0060485	mesenchyme development	17/896	291/18722	0.231912571547635	0.401523729899884	S100A4/IL1B/FLNA/STAT1/MEF2C/GLIPR2/TGFB1/ZFP36L1/DDX5/ROCK1/SDCBP/PTEN/HIF1A/MAPK1/TGFBR2/CORO1C/MDM4	17
GO:0008654	phospholipid biosynthetic process	15/896	253/18722	0.232276541070875	0.401886324055097	SOCS3/PLSCR1/LPGAT1/LPCAT2/INPP5D/SPTLC2/CAPN2/CHP1/PTEN/DGKZ/MBOAT7/ATM/PIP4K2A/FAR1/SMG1	15
GO:0060828	regulation of canonical Wnt signaling pathway	15/896	253/18722	0.232276541070875	0.401886324055097	ZEB2/LRRK2/EGR1/TGFB1/SULF2/PFDN5/HHEX/STK4/GNAQ/CCNY/CYLD/ATP6AP2/DDX3X/WNK1/NFKB1	15
GO:0007020	microtubule nucleation	3/896	35/18722	0.233925247750916	0.403263246122809	HSPA1A/NIN/PAK1	3
GO:0009119	ribonucleoside metabolic process	3/896	35/18722	0.233925247750916	0.403263246122809	APOBEC3A/CDA/UPP1	3
GO:0010765	positive regulation of sodium ion transport	3/896	35/18722	0.233925247750916	0.403263246122809	GLRX/CHP1/WNK1	3
GO:0010837	regulation of keratinocyte proliferation	3/896	35/18722	0.233925247750916	0.403263246122809	ZFP36/NOTCH2/ZFP36L1	3
GO:0032205	negative regulation of telomere maintenance	3/896	35/18722	0.233925247750916	0.403263246122809	ATM/HNRNPU/XRN1	3
GO:0032350	regulation of hormone metabolic process	3/896	35/18722	0.233925247750916	0.403263246122809	EGR1/HIF1A/NFKB1	3
GO:0034331	cell junction maintenance	3/896	35/18722	0.233925247750916	0.403263246122809	CSF1R/CHCHD10/CTBP2	3
GO:0045454	cell redox homeostasis	3/896	35/18722	0.233925247750916	0.403263246122809	SLC11A1/GPX1/HVCN1	3
GO:0045907	positive regulation of vasoconstriction	3/896	35/18722	0.233925247750916	0.403263246122809	PTGS2/RHOA/TBXAS1	3
GO:0070536	protein K63-linked deubiquitination	3/896	35/18722	0.233925247750916	0.403263246122809	TNFAIP3/OTUD1/CYLD	3
GO:1905207	regulation of cardiocyte differentiation	3/896	35/18722	0.233925247750916	0.403263246122809	ARRB2/MEF2C/TGFB1	3
GO:0009145	purine nucleoside triphosphate biosynthetic process	5/896	69/18722	0.234357663808097	0.40347375354714	TMSB4X/TGFB1/PRKAG2/ATP6V1A/STAT3	5
GO:0033344	cholesterol efflux	5/896	69/18722	0.234357663808097	0.40347375354714	NFKBIA/NPC2/RXRA/LAMTOR1/STX12	5
GO:0045669	positive regulation of osteoblast differentiation	5/896	69/18722	0.234357663808097	0.40347375354714	MEF2C/CEBPB/IL6R/JUND/CLIC1	5
GO:0050810	regulation of steroid biosynthetic process	5/896	69/18722	0.234357663808097	0.40347375354714	TSPO/EGR1/TNF/ASAH1/NFKB1	5
GO:0071482	cellular response to light stimulus	8/896	123/18722	0.236274273968725	0.406638814993825	CRIP1/CARD16/TIMP1/PTGS2/CDKN1A/POLK/CREBBP/EP300	8
GO:0034249	negative regulation of cellular amide metabolic process	16/896	273/18722	0.236573552735742	0.40688460574689	ZFP36/RGS2/ZFP36L2/BTG2/PABPC1/SORL1/ZFP36L1/EIF4EBP1/RTN3/STAT3/ROCK1/YBX1/CELF1/DDX3X/PRNP/XRN1	16
GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	16/896	273/18722	0.236573552735742	0.40688460574689	ITGB2/JAML/FXYD5/KLF4/SELL/PECAM1/IL1RN/MYADM/ITGAL/ITGAM/MBP/CD84/PLXNB2/TGFBR2/WNK1/EMB	16
GO:0010662	regulation of striated muscle cell apoptotic process	4/896	52/18722	0.237068006845491	0.407196401454226	JAK2/CAPN2/CFLAR/PTEN	4
GO:0030514	negative regulation of BMP signaling pathway	4/896	52/18722	0.237068006845491	0.407196401454226	SORL1/UBE2D1/SKIL/UBE2D3	4
GO:0048260	positive regulation of receptor-mediated endocytosis	4/896	52/18722	0.237068006845491	0.407196401454226	B2M/ARRB2/PPT1/SYK	4
GO:0072523	purine-containing compound catabolic process	4/896	52/18722	0.237068006845491	0.407196401454226	SAMHD1/DPYD/NUDT16/NUDT3	4
GO:0044070	regulation of anion transport	6/896	87/18722	0.237201583692749	0.407291329411022	IL1B/RGS2/CEBPB/SYK/PTAFR/PRNP	6
GO:0016079	synaptic vesicle exocytosis	7/896	105/18722	0.237480721926699	0.407636051069558	LRRK2/PRKCB/STX11/RAP1A/RAP1B/CTBP2/BLOC1S6	7
GO:0007009	plasma membrane organization	9/896	142/18722	0.24030070339011	0.41220447174537	S100A9/PTPRC/PLSCR1/CXCR4/SERP1/PTEN/BIN2/MYH9/PLEC	9
GO:0072006	nephron development	9/896	142/18722	0.24030070339011	0.41220447174537	EGR1/STAT1/MEF2C/PECAM1/IQGAP1/NOTCH2/SULF2/IL6R/CFLAR	9
GO:0048167	regulation of synaptic plasticity	12/896	198/18722	0.240507347440606	0.412422919234616	TYROBP/PTGS2/LILRB2/MEF2C/CX3CR1/NRGN/MCTP1/PTK2B/PTEN/MAPK1/PRNP/CREB1	12
GO:0045787	positive regulation of cell cycle	18/896	313/18722	0.243668139203269	0.417705336847792	AIF1/IL1B/PLSCR1/RHOA/EIF4EBP1/NUDT16/CDC42/KMT2E/CCNY/RB1/CCPG1/HNRNPU/PHIP/LSM10/ADAM17/DDX3X/NUP62/DYNC1LI1	18
GO:0071897	DNA biosynthetic process	11/896	180/18722	0.24471617828438	0.419363704532804	DUSP1/KLF4/ARRB2/PTK2B/CDKN1A/POLK/MAPK1/ATM/HNRNPU/POLE4/XRN1	11
GO:1901657	glycosyl compound metabolic process	6/896	88/18722	0.245172383578924	0.419600728643362	TYMP/APOBEC3A/DPYD/CDA/UPP1/NAGA	6
GO:1901617	organic hydroxy compound biosynthetic process	14/896	237/18722	0.2462237853008	0.419600728643362	ZEB2/PLEK/NR4A2/TNF/PTAFR/GCH1/PTK2B/SPTLC2/G6PD/PRKAG2/ASAH1/LBR/PPIP5K2/NFKB1	14
GO:0017004	cytochrome complex assembly	3/896	36/18722	0.246862305444167	0.419600728643362	CYBA/SCO2/OXA1L	3
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	3/896	36/18722	0.246862305444167	0.419600728643362	HLA-DRB1/NADK/HIF1A	3
GO:0036314	response to sterol	3/896	36/18722	0.246862305444167	0.419600728643362	CCL3/TGFB1/TGFBR2	3
GO:0051354	negative regulation of oxidoreductase activity	3/896	36/18722	0.246862305444167	0.419600728643362	LRRK2/OXA1L/NFKB1	3
GO:1903749	positive regulation of establishment of protein localization to mitochondrion	3/896	36/18722	0.246862305444167	0.419600728643362	RAC2/UBE2D3/TOMM7	3
GO:0032210	regulation of telomere maintenance via telomerase	4/896	53/18722	0.247563509841384	0.419600728643362	MAPK1/ATM/HNRNPU/XRN1	4
GO:0034381	plasma lipoprotein particle clearance	4/896	53/18722	0.247563509841384	0.419600728643362	CD36/CSK/LIPA/HMOX1	4
GO:0043113	receptor clustering	4/896	53/18722	0.247563509841384	0.419600728643362	ITGB2/FLNA/ITGA4/ITGAL	4
GO:0046394	carboxylic acid biosynthetic process	18/896	314/18722	0.247818166354176	0.419600728643362	IL1B/CD74/PTGS2/DPYD/LTA4H/HACD4/SYK/ALOX5/TBXAS1/LPGAT1/ALDH1A1/KYNU/GLUL/PDK4/ALOX5AP/PRKAG2/ELOVL5/QKI	18
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	2/896	20/18722	0.248000892107228	0.419600728643362	BACH1/RB1	2
GO:0002834	regulation of response to tumor cell	2/896	20/18722	0.248000892107228	0.419600728643362	HLA-DRB1/AHR	2
GO:0002837	regulation of immune response to tumor cell	2/896	20/18722	0.248000892107228	0.419600728643362	HLA-DRB1/AHR	2
GO:0006700	C21-steroid hormone biosynthetic process	2/896	20/18722	0.248000892107228	0.419600728643362	TSPO/EGR1	2
GO:0006837	serotonin transport	2/896	20/18722	0.248000892107228	0.419600728643362	LILRB1/SYK	2
GO:0009110	vitamin biosynthetic process	2/896	20/18722	0.248000892107228	0.419600728643362	TNF/NFKB1	2
GO:0009713	catechol-containing compound biosynthetic process	2/896	20/18722	0.248000892107228	0.419600728643362	NR4A2/GCH1	2
GO:0010523	negative regulation of calcium ion transport into cytosol	2/896	20/18722	0.248000892107228	0.419600728643362	CALM2/TMBIM6	2
GO:0032211	negative regulation of telomere maintenance via telomerase	2/896	20/18722	0.248000892107228	0.419600728643362	HNRNPU/XRN1	2
GO:0033005	positive regulation of mast cell activation	2/896	20/18722	0.248000892107228	0.419600728643362	FGR/SYK	2
GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate	2/896	20/18722	0.248000892107228	0.419600728643362	APOBEC3A/CXCL8	2
GO:0042359	vitamin D metabolic process	2/896	20/18722	0.248000892107228	0.419600728643362	TNF/NFKB1	2
GO:0042423	catecholamine biosynthetic process	2/896	20/18722	0.248000892107228	0.419600728643362	NR4A2/GCH1	2
GO:0043651	linoleic acid metabolic process	2/896	20/18722	0.248000892107228	0.419600728643362	ALOX5/ELOVL5	2
GO:0043984	histone H4-K16 acetylation	2/896	20/18722	0.248000892107228	0.419600728643362	MSL3/KMT2A	2
GO:0045063	T-helper 1 cell differentiation	2/896	20/18722	0.248000892107228	0.419600728643362	STAT6/SPN	2
GO:0045844	positive regulation of striated muscle tissue development	2/896	20/18722	0.248000892107228	0.419600728643362	MEF2C/CREB1	2
GO:0046485	ether lipid metabolic process	2/896	20/18722	0.248000892107228	0.419600728643362	LPCAT2/FAR1	2
GO:0048636	positive regulation of muscle organ development	2/896	20/18722	0.248000892107228	0.419600728643362	MEF2C/CREB1	2
GO:0051900	regulation of mitochondrial depolarization	2/896	20/18722	0.248000892107228	0.419600728643362	TSPO/LRRK2	2
GO:0060044	negative regulation of cardiac muscle cell proliferation	2/896	20/18722	0.248000892107228	0.419600728643362	PTEN/TGFBR2	2
GO:0061003	positive regulation of dendritic spine morphogenesis	2/896	20/18722	0.248000892107228	0.419600728643362	ACTR2/DBNL	2
GO:0061318	renal filtration cell differentiation	2/896	20/18722	0.248000892107228	0.419600728643362	IQGAP1/NOTCH2	2
GO:0072112	glomerular visceral epithelial cell differentiation	2/896	20/18722	0.248000892107228	0.419600728643362	IQGAP1/NOTCH2	2
GO:0090201	negative regulation of release of cytochrome c from mitochondria	2/896	20/18722	0.248000892107228	0.419600728643362	ARRB2/GPX1	2
GO:1990182	exosomal secretion	2/896	20/18722	0.248000892107228	0.419600728643362	RAB27A/SDCBP	2
GO:2000010	positive regulation of protein localization to cell surface	2/896	20/18722	0.248000892107228	0.419600728643362	TYROBP/TNF	2
GO:2000479	regulation of cAMP-dependent protein kinase activity	2/896	20/18722	0.248000892107228	0.419600728643362	PRKAG2/PRKAR1A	2
GO:0006066	alcohol metabolic process	20/896	353/18722	0.249216629516965	0.421520549631784	PLEK/CYP1B1/ALDH2/NPC2/SULT1A1/PTAFR/ALDH1A1/GCH1/APOBR/PTK2B/SPTLC2/NAAA/G6PD/PTEN/RXRA/ASAH1/NUDT3/LBR/PPIP5K2/NFKB1	20
GO:0005996	monosaccharide metabolic process	15/896	257/18722	0.250551516038728	0.423640583523219	SLC2A3/OAS1/TNF/SERP1/FBP1/MIDN/PDK4/G6PD/PGD/PGK1/ATF3/ADPGK/IRS2/PTPN2/EP300	15
GO:0000018	regulation of DNA recombination	7/896	107/18722	0.251988263395003	0.425654744370708	PTPRC/ACTR2/WAS/TGFB1/STAT6/BCL6/SMCHD1	7
GO:0071868	cellular response to monoamine stimulus	7/896	107/18722	0.251988263395003	0.425654744370708	LRRK2/FLNA/ARRB2/PRKACA/MAPK1/GNB1/GNAI3	7
GO:0071870	cellular response to catecholamine stimulus	7/896	107/18722	0.251988263395003	0.425654744370708	LRRK2/FLNA/ARRB2/PRKACA/MAPK1/GNB1/GNAI3	7
GO:0003208	cardiac ventricle morphogenesis	5/896	71/18722	0.252380972755872	0.426041362967637	MEF2C/TGFB1/FKBP1A/HIF1A/TGFBR2	5
GO:0008344	adult locomotory behavior	5/896	71/18722	0.252380972755872	0.426041362967637	ARRB2/NR4A2/PPT1/AGTPBP1/CSTB	5
GO:0031644	regulation of nervous system process	9/896	144/18722	0.252749029046334	0.426524237530818	TYMP/TNFRSF1B/CCL3/LRRK2/ITGAX/PTAFR/PTK2B/PTEN/DICER1	9
GO:0051781	positive regulation of cell division	6/896	89/18722	0.253219715661271	0.427179935502521	IL1B/TGFB1/RHOA/CDC42/YBX1/NUP62	6
GO:0016053	organic acid biosynthetic process	18/896	316/18722	0.256202451117598	0.432060587501015	IL1B/CD74/PTGS2/DPYD/LTA4H/HACD4/SYK/ALOX5/TBXAS1/LPGAT1/ALDH1A1/KYNU/GLUL/PDK4/ALOX5AP/PRKAG2/ELOVL5/QKI	18
GO:0006473	protein acetylation	12/896	201/18722	0.256278967975511	0.432060587501015	IL1B/SPI1/BLOC1S1/MSL3/PHF20L1/TAOK1/DDX3X/TAF10/CREBBP/EP300/KMT2A/EPC1	12
GO:0001706	endoderm formation	4/896	54/18722	0.258157182248233	0.434522817111023	ITGB2/DUSP1/ITGA4/ITGA5	4
GO:0007215	glutamate receptor signaling pathway	4/896	54/18722	0.258157182248233	0.434522817111023	FYN/PTK2B/GNAQ/PRNP	4
GO:0030520	intracellular estrogen receptor signaling pathway	4/896	54/18722	0.258157182248233	0.434522817111023	PAK1/DDX5/NCOA4/ARID1A	4
GO:0070839	metal ion export	4/896	54/18722	0.258157182248233	0.434522817111023	SLC11A1/SLC8A1/KCNE3/CALM2	4
GO:2000300	regulation of synaptic vesicle exocytosis	4/896	54/18722	0.258157182248233	0.434522817111023	LRRK2/PRKCB/RAP1A/RAP1B	4
GO:0014904	myotube cell development	3/896	37/18722	0.25990573908007	0.436477154974311	GPX1/PPP3CA/PLEC	3
GO:0031112	positive regulation of microtubule polymerization or depolymerization	3/896	37/18722	0.25990573908007	0.436477154974311	HSPA1A/NIN/PAK1	3
GO:0032885	regulation of polysaccharide biosynthetic process	3/896	37/18722	0.25990573908007	0.436477154974311	TGFB1/IRS2/NFKB1	3
GO:0034260	negative regulation of GTPase activity	3/896	37/18722	0.25990573908007	0.436477154974311	LRRK2/ARRB2/WNK1	3
GO:0045616	regulation of keratinocyte differentiation	3/896	37/18722	0.25990573908007	0.436477154974311	ZFP36/ZFP36L1/ROCK1	3
GO:0060428	lung epithelium development	3/896	37/18722	0.25990573908007	0.436477154974311	KLF2/CDC42/CREB1	3
GO:1900016	negative regulation of cytokine production involved in inflammatory response	3/896	37/18722	0.25990573908007	0.436477154974311	PYCARD/SIRPA/ADCY7	3
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	6/896	90/18722	0.261338797378298	0.43874211916221	LRRK2/HSPA1A/TRIB1/GABARAP/PIAS1/HERPUD1	6
GO:0050709	negative regulation of protein secretion	5/896	72/18722	0.261519404254674	0.438903653284466	IL1B/UCP2/MIDN/RAB11FIP1/PPP3CA	5
GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	9/896	146/18722	0.265404126360001	0.442370290583844	GNAI2/ADGRE5/ADGRE2/GPR65/AKAP13/GNAQ/ADCY7/GNB1/GNA13	9
GO:0060047	heart contraction	14/896	241/18722	0.265669551411988	0.442370290583844	RGS2/FLNA/CELF2/GPX1/JAK2/HBEGF/SLC8A1/KCNE3/CXCR4/GCH1/CALM2/MEF2A/CDC42/PRKACA	14
GO:0000002	mitochondrial genome maintenance	2/896	21/18722	0.266051580262693	0.442370290583844	TYMP/MEF2A	2
GO:0002689	negative regulation of leukocyte chemotaxis	2/896	21/18722	0.266051580262693	0.442370290583844	DUSP1/RIN3	2
GO:0006067	ethanol metabolic process	2/896	21/18722	0.266051580262693	0.442370290583844	ALDH2/SULT1A1	2
GO:0006450	regulation of translational fidelity	2/896	21/18722	0.266051580262693	0.442370290583844	RPS9/EIF2S3	2
GO:0006925	inflammatory cell apoptotic process	2/896	21/18722	0.266051580262693	0.442370290583844	MEF2C/IRF7	2
GO:0021533	cell differentiation in hindbrain	2/896	21/18722	0.266051580262693	0.442370290583844	AGTPBP1/MTPN	2
GO:0022010	central nervous system myelination	2/896	21/18722	0.266051580262693	0.442370290583844	TLR2/PTEN	2
GO:0032288	myelin assembly	2/896	21/18722	0.266051580262693	0.442370290583844	TLR2/DICER1	2
GO:0032291	axon ensheathment in central nervous system	2/896	21/18722	0.266051580262693	0.442370290583844	TLR2/PTEN	2
GO:0032303	regulation of icosanoid secretion	2/896	21/18722	0.266051580262693	0.442370290583844	IL1B/SYK	2
GO:0035020	regulation of Rac protein signal transduction	2/896	21/18722	0.266051580262693	0.442370290583844	GABARAP/DYNLT1	2
GO:0038083	peptidyl-tyrosine autophosphorylation	2/896	21/18722	0.266051580262693	0.442370290583844	IQGAP1/PTK2B	2
GO:0044342	type B pancreatic cell proliferation	2/896	21/18722	0.266051580262693	0.442370290583844	NR4A1/SERPINB1	2
GO:0044766	multi-organism transport	2/896	21/18722	0.266051580262693	0.442370290583844	BST2/DYNLT1	2
GO:0046514	ceramide catabolic process	2/896	21/18722	0.266051580262693	0.442370290583844	ASAH1/NAGA	2
GO:0051152	positive regulation of smooth muscle cell differentiation	2/896	21/18722	0.266051580262693	0.442370290583844	SOD2/PIAS1	2
GO:0070269	pyroptosis	2/896	21/18722	0.266051580262693	0.442370290583844	CASP1/NAIP	2
GO:0072311	glomerular epithelial cell differentiation	2/896	21/18722	0.266051580262693	0.442370290583844	IQGAP1/NOTCH2	2
GO:0097062	dendritic spine maintenance	2/896	21/18722	0.266051580262693	0.442370290583844	FYN/PRNP	2
GO:0097734	extracellular exosome biogenesis	2/896	21/18722	0.266051580262693	0.442370290583844	RAB27A/SDCBP	2
GO:0150146	cell junction disassembly	2/896	21/18722	0.266051580262693	0.442370290583844	CX3CR1/ITGAM	2
GO:1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	2/896	21/18722	0.266051580262693	0.442370290583844	HSPA1A/CHCHD10	2
GO:1901863	positive regulation of muscle tissue development	2/896	21/18722	0.266051580262693	0.442370290583844	MEF2C/CREB1	2
GO:1902473	regulation of protein localization to synapse	2/896	21/18722	0.266051580262693	0.442370290583844	RAP1A/ADAM10	2
GO:1902579	multi-organism localization	2/896	21/18722	0.266051580262693	0.442370290583844	BST2/DYNLT1	2
GO:1903429	regulation of cell maturation	2/896	21/18722	0.266051580262693	0.442370290583844	LRRK2/CLEC7A	2
GO:2001014	regulation of skeletal muscle cell differentiation	2/896	21/18722	0.266051580262693	0.442370290583844	MEF2C/DDX5	2
GO:0043266	regulation of potassium ion transport	7/896	109/18722	0.266752646110019	0.443394219373029	FLNA/KCNE3/PTK2B/PTEN/CAB39/PRNP/WNK1	7
GO:0007051	spindle organization	11/896	184/18722	0.267081105902644	0.443656605493341	FLNA/RHOA/HSPA1A/CCDC69/SUN2/STAG2/HNRNPU/MYH9/CHMP1B/NUP62/ZNF207	11
GO:2001257	regulation of cation channel activity	11/896	184/18722	0.267081105902644	0.443656605493341	CTSS/TMSB4X/MEF2C/IFNGR2/CCR2/KCNE3/PTK2B/FKBP1A/AHNAK/CALM2/PRKACA	11
GO:0046164	alcohol catabolic process	4/896	55/18722	0.268838045923962	0.446432527730053	ALDH2/SULT1A1/PTEN/NUDT3	4
GO:0006639	acylglycerol metabolic process	8/896	128/18722	0.269990995711743	0.447775245120145	GPX1/SORL1/LPGAT1/APOBR/ACSL1/DGKZ/ACSL4/MBOAT7	8
GO:0033865	nucleoside bisphosphate metabolic process	8/896	128/18722	0.269990995711743	0.447775245120145	PPT1/SULT1A1/KYNU/ACSL1/PDK4/ELOVL5/ACSL4/FAR1	8
GO:0033875	ribonucleoside bisphosphate metabolic process	8/896	128/18722	0.269990995711743	0.447775245120145	PPT1/SULT1A1/KYNU/ACSL1/PDK4/ELOVL5/ACSL4/FAR1	8
GO:0034032	purine nucleoside bisphosphate metabolic process	8/896	128/18722	0.269990995711743	0.447775245120145	PPT1/SULT1A1/KYNU/ACSL1/PDK4/ELOVL5/ACSL4/FAR1	8
GO:0045739	positive regulation of DNA repair	5/896	73/18722	0.270733122247957	0.448862916420664	ACTR2/WAS/PARP9/SMCHD1/DTX3L	5
GO:0060041	retina development in camera-type eye	9/896	147/18722	0.271803785736777	0.450494419890688	CYP1B1/TCIRG1/PFDN5/AGTPBP1/HIF1A/GNB1/XRN2/HIPK1/MAX	9
GO:0006869	lipid transport	22/896	398/18722	0.272680387832285	0.451385158353054	IL1B/TSPO/NFKBIA/CD36/PSAP/RETN/APOL6/NPC2/SYK/PLSCR1/SLCO3A1/AQP9/APOBR/ACSL1/OSBPL8/RXRA/ACSL4/PIP4K2A/LAMTOR1/IRS2/NFKB1/STX12	22
GO:0008210	estrogen metabolic process	3/896	38/18722	0.273035513973987	0.451385158353054	CYP1B1/HSD17B11/SULT1A1	3
GO:0032717	negative regulation of interleukin-8 production	3/896	38/18722	0.273035513973987	0.451385158353054	TMSB4X/KLF4/CD33	3
GO:0046676	negative regulation of insulin secretion	3/896	38/18722	0.273035513973987	0.451385158353054	UCP2/MIDN/PPP3CA	3
GO:0048713	regulation of oligodendrocyte differentiation	3/896	38/18722	0.273035513973987	0.451385158353054	TNFRSF1B/TLR2/CXCR4	3
GO:0071398	cellular response to fatty acid	3/896	38/18722	0.273035513973987	0.451385158353054	PTAFR/PDK4/CREB1	3
GO:1901031	regulation of response to reactive oxygen species	3/896	38/18722	0.273035513973987	0.451385158353054	LRRK2/CD36/GCH1	3
GO:1903580	positive regulation of ATP metabolic process	3/896	38/18722	0.273035513973987	0.451385158353054	TMSB4X/STAT3/HIF1A	3
GO:0003014	renal system process	7/896	110/18722	0.274222314572757	0.452915293138429	CYBA/GNAI2/SULF2/RHOA/PKN1/SGK1/PRKACA	7
GO:0006939	smooth muscle contraction	7/896	110/18722	0.274222314572757	0.452915293138429	RGS2/PTGS2/SLC8A1/SULF2/RHOA/PTAFR/ROCK1	7
GO:1905954	positive regulation of lipid localization	7/896	110/18722	0.274222314572757	0.452915293138429	IL1B/NFKBIA/CD36/RETN/ACSL1/RXRA/NFKB1	7
GO:0043543	protein acylation	14/896	243/18722	0.275589929845983	0.455029595279035	IL1B/SPI1/GLUL/BLOC1S1/ZDHHC20/MSL3/PHF20L1/TAOK1/DDX3X/TAF10/CREBBP/EP300/KMT2A/EPC1	14
GO:0006638	neutral lipid metabolic process	8/896	129/18722	0.276896046096156	0.457041045936563	GPX1/SORL1/LPGAT1/APOBR/ACSL1/DGKZ/ACSL4/MBOAT7	8
GO:0031058	positive regulation of histone modification	6/896	92/18722	0.27777301874528	0.458052463695054	IL1B/LRRK2/BCL6/KMT2E/NIPBL/KMT2A	6
GO:1903312	negative regulation of mRNA metabolic process	6/896	92/18722	0.27777301874528	0.458052463695054	ZFP36/SLC11A1/PABPC1/MYD88/YBX1/HNRNPU	6
GO:1903351	cellular response to dopamine	6/896	92/18722	0.27777301874528	0.458052463695054	LRRK2/FLNA/ARRB2/MAPK1/GNB1/GNAI3	6
GO:0044272	sulfur compound biosynthetic process	9/896	148/18722	0.278248583603985	0.458545907263729	PPT1/ACSL1/CSGALNACT2/PDK4/ELOVL5/ACSL4/DSE/SP1/MAT2A	9
GO:0044839	cell cycle G2/M phase transition	9/896	148/18722	0.278248583603985	0.458545907263729	BACH1/CALM2/TAOK3/CDKN1A/CCNY/ATM/NABP1/FOXN3/TAOK1	9
GO:0051058	negative regulation of small GTPase mediated signal transduction	4/896	56/18722	0.279595284480469	0.460619282414609	BCL6/FBP1/TIMP2/NUP62	4
GO:0009201	ribonucleoside triphosphate biosynthetic process	5/896	74/18722	0.280015242438653	0.46101908069751	TMSB4X/TGFB1/PRKAG2/ATP6V1A/STAT3	5
GO:0070972	protein localization to endoplasmic reticulum	5/896	74/18722	0.280015242438653	0.46101908069751	LRRK2/PPP1R15A/RAB10/SPCS3/HERPUD1	5
GO:0071867	response to monoamine	7/896	111/18722	0.281745553693797	0.463427775066869	LRRK2/FLNA/ARRB2/PRKACA/MAPK1/GNB1/GNAI3	7
GO:0071869	response to catecholamine	7/896	111/18722	0.281745553693797	0.463427775066869	LRRK2/FLNA/ARRB2/PRKACA/MAPK1/GNB1/GNAI3	7
GO:0090288	negative regulation of cellular response to growth factor stimulus	7/896	111/18722	0.281745553693797	0.463427775066869	SORL1/SULF2/HHEX/UBE2D1/SKIL/CFLAR/UBE2D3	7
GO:0006662	glycerol ether metabolic process	2/896	22/18722	0.284098745343895	0.465531686998613	LPCAT2/FAR1	2
GO:0007398	ectoderm development	2/896	22/18722	0.284098745343895	0.465531686998613	ITGAM/ETS2	2
GO:0032402	melanosome transport	2/896	22/18722	0.284098745343895	0.465531686998613	RAB27A/BLOC1S6	2
GO:0032693	negative regulation of interleukin-10 production	2/896	22/18722	0.284098745343895	0.465531686998613	TYROBP/LILRB1	2
GO:0032891	negative regulation of organic acid transport	2/896	22/18722	0.284098745343895	0.465531686998613	RGS2/IRS2	2
GO:0033617	mitochondrial cytochrome c oxidase assembly	2/896	22/18722	0.284098745343895	0.465531686998613	SCO2/OXA1L	2
GO:0034629	cellular protein-containing complex localization	2/896	22/18722	0.284098745343895	0.465531686998613	TNFAIP2/RALB	2
GO:0045663	positive regulation of myoblast differentiation	2/896	22/18722	0.284098745343895	0.465531686998613	MEF2C/BTG1	2
GO:0071467	cellular response to pH	2/896	22/18722	0.284098745343895	0.465531686998613	HVCN1/CHP1	2
GO:1900543	negative regulation of purine nucleotide metabolic process	2/896	22/18722	0.284098745343895	0.465531686998613	FBP1/STAT3	2
GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	2/896	22/18722	0.284098745343895	0.465531686998613	HIF1A/EP300	2
GO:2000193	positive regulation of fatty acid transport	2/896	22/18722	0.284098745343895	0.465531686998613	IL1B/ACSL1	2
GO:0009411	response to UV	9/896	149/18722	0.284736297882717	0.466135815325153	CRIP1/CARD16/TIMP1/PTGS2/GPX1/CDKN1A/POLK/CREBBP/EP300	9
GO:0016525	negative regulation of angiogenesis	9/896	149/18722	0.284736297882717	0.466135815325153	KLF2/KLF4/STAT1/CCR2/TNF/ALOX5/HHEX/ROCK1/PGK1	9
GO:1905039	carboxylic acid transmembrane transport	9/896	149/18722	0.284736297882717	0.466135815325153	RGS2/CD36/SLC7A7/AQP9/ACSL1/SLC16A3/MPC1/IRS2/EMB	9
GO:0007589	body fluid secretion	6/896	93/18722	0.286078557366905	0.467407944511715	CYBA/OAS2/HIF1A/USF2/WNK1/CREB1	6
GO:1901019	regulation of calcium ion transmembrane transporter activity	6/896	93/18722	0.286078557366905	0.467407944511715	VMP1/KCNE3/FKBP1A/AHNAK/CALM2/PRKACA	6
GO:1901992	positive regulation of mitotic cell cycle phase transition	6/896	93/18722	0.286078557366905	0.467407944511715	AIF1/KMT2E/RB1/LSM10/ADAM17/DDX3X	6
GO:1903350	response to dopamine	6/896	93/18722	0.286078557366905	0.467407944511715	LRRK2/FLNA/ARRB2/MAPK1/GNB1/GNAI3	6
GO:0010463	mesenchymal cell proliferation	3/896	39/18722	0.286232321336246	0.467407944511715	STAT1/TGFBR2/IRS2	3
GO:0071548	response to dexamethasone	3/896	39/18722	0.286232321336246	0.467407944511715	PTAFR/CFLAR/NR3C1	3
GO:1901021	positive regulation of calcium ion transmembrane transporter activity	3/896	39/18722	0.286232321336246	0.467407944511715	VMP1/KCNE3/CALM2	3
GO:1902742	apoptotic process involved in development	3/896	39/18722	0.286232321336246	0.467407944511715	TNFRSF1B/SPI1/TNFRSF1A	3
GO:0015850	organic hydroxy compound transport	16/896	284/18722	0.286478240030529	0.467662688762958	TSPO/NFKBIA/CD36/ACTB/LILRB1/NPC2/SYK/AQP9/SLC16A3/OSBPL8/RXRA/PIP4K2A/LAMTOR1/NFKB1/STX12/EMB	16
GO:0006024	glycosaminoglycan biosynthetic process	5/896	75/18722	0.289358927712247	0.471625127869444	IL1B/TGFB1/CSGALNACT2/DSE/NFKB1	5
GO:0006094	gluconeogenesis	5/896	75/18722	0.289358927712247	0.471625127869444	FBP1/PGK1/ATF3/PTPN2/EP300	5
GO:0008088	axo-dendritic transport	5/896	75/18722	0.289358927712247	0.471625127869444	BLOC1S1/AGTPBP1/HIF1A/HNRNPU/BLOC1S6	5
GO:0036465	synaptic vesicle recycling	5/896	75/18722	0.289358927712247	0.471625127869444	LRRK2/ACTB/PICALM/ITSN2/ROCK1	5
GO:0045913	positive regulation of carbohydrate metabolic process	5/896	75/18722	0.289358927712247	0.471625127869444	PTAFR/HIF1A/IRS2/PTPN2/NFKB1	5
GO:0016447	somatic recombination of immunoglobulin gene segments	4/896	57/18722	0.290418264870391	0.472759122250674	PTPRC/TGFB1/STAT6/BCL6	4
GO:0051785	positive regulation of nuclear division	4/896	57/18722	0.290418264870391	0.472759122250674	IL1B/RB1/PHIP/NUP62	4
GO:0061005	cell differentiation involved in kidney development	4/896	57/18722	0.290418264870391	0.472759122250674	STAT1/MEF2C/IQGAP1/NOTCH2	4
GO:0097120	receptor localization to synapse	4/896	57/18722	0.290418264870391	0.472759122250674	TYROBP/RAP1A/ADAM10/STX7	4
GO:0019827	stem cell population maintenance	8/896	131/18722	0.290845820509931	0.473153728344619	ZFP36L2/SPI1/KLF4/NOTCH2/STAT3/KLF10/NIPBL/HOOK3	8
GO:0000075	cell cycle checkpoint signaling	10/896	169/18722	0.290933594163833	0.473153728344619	DUSP1/TAOK3/CDKN1A/ATM/NABP1/FOXN3/TAOK1/WAC/ZNF207/DYNC1LI1	10
GO:0018394	peptidyl-lysine acetylation	10/896	169/18722	0.290933594163833	0.473153728344619	IL1B/SPI1/BLOC1S1/MSL3/PHF20L1/TAF10/CREBBP/EP300/KMT2A/EPC1	10
GO:1903825	organic acid transmembrane transport	9/896	150/18722	0.291264693023269	0.473544128919669	RGS2/CD36/SLC7A7/AQP9/ACSL1/SLC16A3/MPC1/IRS2/EMB	9
GO:0006836	neurotransmitter transport	12/896	208/18722	0.294391728011554	0.478252675088362	STXBP2/LRRK2/NR4A1/MEF2C/PPT1/PRKCB/STX11/MCTP1/RAP1A/RAP1B/CTBP2/BLOC1S6	12
GO:0010389	regulation of G2/M transition of mitotic cell cycle	6/896	94/18722	0.294436659417984	0.478252675088362	TAOK3/CDKN1A/ATM/NABP1/FOXN3/TAOK1	6
GO:0014020	primary neural tube formation	6/896	94/18722	0.294436659417984	0.478252675088362	VASP/TGFB1/PRKACA/PFN1/HIF1A/PLXNB2	6
GO:0071333	cellular response to glucose stimulus	9/896	151/18722	0.297831522465554	0.483461133717722	CYBA/LGALS1/HLA-DRB1/UCP2/NADK/PRKACA/HIF1A/IRS2/PPP3CA	9
GO:2000181	negative regulation of blood vessel morphogenesis	9/896	151/18722	0.297831522465554	0.483461133717722	KLF2/KLF4/STAT1/CCR2/TNF/ALOX5/HHEX/ROCK1/PGK1	9
GO:0016055	Wnt signaling pathway	24/896	444/18722	0.297922117586098	0.483461133717722	ZEB2/LRRK2/EGR1/KLF4/TNFAIP3/RNF213/NR4A2/TLR2/TGFB1/SULF2/RHOA/PFDN5/HHEX/STK4/CDC42/GNAQ/CCNY/PTEN/CYLD/ATP6AP2/MBD2/DDX3X/WNK1/NFKB1	24
GO:0045685	regulation of glial cell differentiation	5/896	76/18722	0.298757400357731	0.484665389663306	TNFRSF1B/TLR2/TGFB1/CXCR4/DICER1	5
GO:0031297	replication fork processing	3/896	40/18722	0.29947759983919	0.484926213189173	SAMHD1/FAM111A/BOD1L1	3
GO:0035329	hippo signaling	3/896	40/18722	0.29947759983919	0.484926213189173	MOB1A/STK4/PJA2	3
GO:0043001	Golgi to plasma membrane protein transport	3/896	40/18722	0.29947759983919	0.484926213189173	VAMP5/CSK/RAB10	3
GO:0045777	positive regulation of blood pressure	3/896	40/18722	0.29947759983919	0.484926213189173	CYBA/RHOA/WNK1	3
GO:0097352	autophagosome maturation	3/896	40/18722	0.29947759983919	0.484926213189173	VMP1/CALCOCO2/LAMP2	3
GO:2000142	regulation of DNA-templated transcription, initiation	3/896	40/18722	0.29947759983919	0.484926213189173	JUN/SETX/CREB1	3
GO:0140014	mitotic nuclear division	16/896	287/18722	0.300659752472184	0.485097100459177	IL1B/DUSP1/FLNA/RHOA/HSPA1A/CDC42/RB1/NIPBL/ATM/STAG2/HNRNPU/PHIP/CHMP1B/NUP62/ZNF207/DYNC1LI1	16
GO:0006826	iron ion transport	4/896	58/18722	0.301296556917095	0.485097100459177	B2M/SLC11A1/FTL/FTH1	4
GO:0018208	peptidyl-proline modification	4/896	58/18722	0.301296556917095	0.485097100459177	FKBP5/FKBP1A/FKBP15/CRTAP	4
GO:0032387	negative regulation of intracellular transport	4/896	58/18722	0.301296556917095	0.485097100459177	LRRK2/CD36/SP100/CHP1	4
GO:0086065	cell communication involved in cardiac conduction	4/896	58/18722	0.301296556917095	0.485097100459177	FLNA/SLC8A1/CALM2/PRKACA	4
GO:2000649	regulation of sodium ion transmembrane transporter activity	4/896	58/18722	0.301296556917095	0.485097100459177	FXYD5/GLRX/CHP1/WNK1	4
GO:0001919	regulation of receptor recycling	2/896	23/18722	0.302101424415934	0.485097100459177	ARAP1/LAMTOR1	2
GO:0002052	positive regulation of neuroblast proliferation	2/896	23/18722	0.302101424415934	0.485097100459177	CX3CR1/HIF1A	2
GO:0003283	atrial septum development	2/896	23/18722	0.302101424415934	0.485097100459177	NOTCH2/MDM4	2
GO:0021544	subpallium development	2/896	23/18722	0.302101424415934	0.485097100459177	LRRK2/ZSWIM6	2
GO:0032401	establishment of melanosome localization	2/896	23/18722	0.302101424415934	0.485097100459177	RAB27A/BLOC1S6	2
GO:0032740	positive regulation of interleukin-17 production	2/896	23/18722	0.302101424415934	0.485097100459177	TGFB1/MYD88	2
GO:0034105	positive regulation of tissue remodeling	2/896	23/18722	0.302101424415934	0.485097100459177	ROCK1/PPP3CA	2
GO:0043931	ossification involved in bone maturation	2/896	23/18722	0.302101424415934	0.485097100459177	SNX10/RHOA	2
GO:0045662	negative regulation of myoblast differentiation	2/896	23/18722	0.302101424415934	0.485097100459177	TGFB1/TNF	2
GO:0045932	negative regulation of muscle contraction	2/896	23/18722	0.302101424415934	0.485097100459177	RGS2/PTGS2	2
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	2/896	23/18722	0.302101424415934	0.485097100459177	CSGALNACT2/DSE	2
GO:0051904	pigment granule transport	2/896	23/18722	0.302101424415934	0.485097100459177	RAB27A/BLOC1S6	2
GO:0060353	regulation of cell adhesion molecule production	2/896	23/18722	0.302101424415934	0.485097100459177	IL1B/CXCL8	2
GO:0060384	innervation	2/896	23/18722	0.302101424415934	0.485097100459177	ITGA4/SULF2	2
GO:0060487	lung epithelial cell differentiation	2/896	23/18722	0.302101424415934	0.485097100459177	KLF2/CREB1	2
GO:0060547	negative regulation of necrotic cell death	2/896	23/18722	0.302101424415934	0.485097100459177	BIRC3/BIRC2	2
GO:0060575	intestinal epithelial cell differentiation	2/896	23/18722	0.302101424415934	0.485097100459177	CDKN1A/HIF1A	2
GO:0071514	genetic imprinting	2/896	23/18722	0.302101424415934	0.485097100459177	KDM1B/ARID4A	2
GO:0140112	extracellular vesicle biogenesis	2/896	23/18722	0.302101424415934	0.485097100459177	RAB27A/SDCBP	2
GO:1900273	positive regulation of long-term synaptic potentiation	2/896	23/18722	0.302101424415934	0.485097100459177	NRGN/CREB1	2
GO:2001169	regulation of ATP biosynthetic process	2/896	23/18722	0.302101424415934	0.485097100459177	TMSB4X/STAT3	2
GO:0030516	regulation of axon extension	6/896	95/18722	0.302842553971495	0.485837175572407	ARHGAP4/DPYSL2/SHTN1/PAK1/TWF2/DBNL	6
GO:0048709	oligodendrocyte differentiation	6/896	95/18722	0.302842553971495	0.485837175572407	TNFRSF1B/LYN/TLR2/CSK/CXCR4/PTEN	6
GO:1901379	regulation of potassium ion transmembrane transport	6/896	95/18722	0.302842553971495	0.485837175572407	FLNA/KCNE3/PTEN/CAB39/PRNP/WNK1	6
GO:0016573	histone acetylation	9/896	152/18722	0.304434531062861	0.487639050218028	IL1B/SPI1/MSL3/PHF20L1/TAF10/CREBBP/EP300/KMT2A/EPC1	9
GO:0021915	neural tube development	9/896	152/18722	0.304434531062861	0.487639050218028	VASP/TGFB1/ZFP36L1/STK4/PRKACA/PFN1/HIF1A/PLXNB2/ATP6AP2	9
GO:0030509	BMP signaling pathway	9/896	152/18722	0.304434531062861	0.487639050218028	EGR1/USP15/TGFB1/NOTCH2/SORL1/UBE2D1/SKIL/DDX5/UBE2D3	9
GO:0031056	regulation of histone modification	9/896	152/18722	0.304434531062861	0.487639050218028	IL1B/SPI1/LRRK2/BCL6/KMT2E/NIPBL/KMT2A/KDM5A/TRIP12	9
GO:1901343	negative regulation of vasculature development	9/896	152/18722	0.304434531062861	0.487639050218028	KLF2/KLF4/STAT1/CCR2/TNF/ALOX5/HHEX/ROCK1/PGK1	9
GO:0198738	cell-cell signaling by wnt	24/896	446/18722	0.305574310457851	0.489314035927119	ZEB2/LRRK2/EGR1/KLF4/TNFAIP3/RNF213/NR4A2/TLR2/TGFB1/SULF2/RHOA/PFDN5/HHEX/STK4/CDC42/GNAQ/CCNY/PTEN/CYLD/ATP6AP2/MBD2/DDX3X/WNK1/NFKB1	24
GO:0006164	purine nucleotide biosynthetic process	11/896	191/18722	0.307681033083862	0.492535873520827	TMSB4X/PPT1/TGFB1/ACSL1/PDK4/PRKAG2/ELOVL5/ATP6V1A/STAT3/ADCY7/ACSL4	11
GO:0007492	endoderm development	5/896	77/18722	0.308203953549332	0.492917823619335	ITGB2/DUSP1/ITGA4/ZFP36L1/ITGA5	5
GO:0021675	nerve development	5/896	77/18722	0.308203953549332	0.492917823619335	MAFB/ITGA4/SULF2/TCIRG1/DICER1	5
GO:1901983	regulation of protein acetylation	5/896	77/18722	0.308203953549332	0.492917823619335	IL1B/SPI1/TAOK1/DDX3X/KMT2A	5
GO:0071331	cellular response to hexose stimulus	9/896	153/18722	0.311071457465952	0.497091515543065	CYBA/LGALS1/HLA-DRB1/UCP2/NADK/PRKACA/HIF1A/IRS2/PPP3CA	9
GO:0042180	cellular ketone metabolic process	12/896	211/18722	0.311203379515865	0.497091515543065	IL1B/CD74/EGR1/PTGS2/SLC7A7/LPGAT1/KYNU/PDK4/PRKAG2/ELOVL5/NQO2/IRS2	12
GO:0046474	glycerophospholipid biosynthetic process	12/896	211/18722	0.311203379515865	0.497091515543065	SOCS3/PLSCR1/LPCAT2/INPP5D/CAPN2/PTEN/DGKZ/MBOAT7/ATM/PIP4K2A/FAR1/SMG1	12
GO:0044264	cellular polysaccharide metabolic process	6/896	96/18722	0.311291495120893	0.497091515543065	AOAH/CSGALNACT2/PRKAG2/PYGL/IRS2/RB1CC1	6
GO:0051304	chromosome separation	6/896	96/18722	0.311291495120893	0.497091515543065	DUSP1/PLSCR1/RB1/ATM/ZNF207/DYNC1LI1	6
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	8/896	134/18722	0.31207784254371	0.49794193200028	LRRK2/HSPA1A/TRIB1/GABARAP/SDCBP/PIAS1/WAC/HERPUD1	8
GO:0098727	maintenance of cell number	8/896	134/18722	0.31207784254371	0.49794193200028	ZFP36L2/SPI1/KLF4/NOTCH2/STAT3/KLF10/NIPBL/HOOK3	8
GO:0033013	tetrapyrrole metabolic process	4/896	59/18722	0.312219950872141	0.49794193200028	TSPO/BLVRB/BLVRA/HMOX1	4
GO:0090303	positive regulation of wound healing	4/896	59/18722	0.312219950872141	0.49794193200028	CLEC7A/CD36/HBEGF/CXCR4	4
GO:0043279	response to alkaloid	7/896	115/18722	0.312302746045936	0.49794193200028	AIF1/FOSB/SLC8A1/CXCR4/PTK2B/HNMT/PEA15	7
GO:0060612	adipose tissue development	3/896	41/18722	0.312753551320146	0.498202517738463	SPI1/SORL1/SPTLC2	3
GO:1900371	regulation of purine nucleotide biosynthetic process	3/896	41/18722	0.312753551320146	0.498202517738463	TMSB4X/PDK4/STAT3	3
GO:2000008	regulation of protein localization to cell surface	3/896	41/18722	0.312753551320146	0.498202517738463	TYROBP/TNF/PICALM	3
GO:0010876	lipid localization	24/896	448/18722	0.313288863207494	0.498902442603239	IL1B/TSPO/NFKBIA/CD36/PSAP/RETN/APOL6/NPC2/SYK/PLSCR1/TNF/SLCO3A1/AQP9/APOBR/ACSL1/OSBPL8/RXRA/ACSL4/PIP4K2A/LAMTOR1/IRS2/PTPN2/NFKB1/STX12	24
GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	5/896	78/18722	0.317691962096194	0.50490862500845	RGS2/FLNA/GNAI2/PSAP/GNAI3	5
GO:0019319	hexose biosynthetic process	5/896	78/18722	0.317691962096194	0.50490862500845	FBP1/PGK1/ATF3/PTPN2/EP300	5
GO:0032371	regulation of sterol transport	5/896	78/18722	0.317691962096194	0.50490862500845	TSPO/NFKBIA/RXRA/LAMTOR1/NFKB1	5
GO:0032374	regulation of cholesterol transport	5/896	78/18722	0.317691962096194	0.50490862500845	TSPO/NFKBIA/RXRA/LAMTOR1/NFKB1	5
GO:0043537	negative regulation of blood vessel endothelial cell migration	5/896	78/18722	0.317691962096194	0.50490862500845	KLF4/MEF2C/TGFB1/TNF/RHOA	5
GO:0030856	regulation of epithelial cell differentiation	9/896	154/18722	0.317740036464652	0.50490862500845	IL1B/ZFP36/STAT1/CEBPB/TNF/ZFP36L1/BTG1/TNFRSF1A/ROCK1	9
GO:0071326	cellular response to monosaccharide stimulus	9/896	154/18722	0.317740036464652	0.50490862500845	CYBA/LGALS1/HLA-DRB1/UCP2/NADK/PRKACA/HIF1A/IRS2/PPP3CA	9
GO:0010596	negative regulation of endothelial cell migration	6/896	97/18722	0.319778768813504	0.505168246098148	KLF4/MEF2C/TGFB1/TNF/RHOA/SP100	6
GO:0001779	natural killer cell differentiation	2/896	24/18722	0.3200225750856	0.505168246098148	PTPRC/SP3	2
GO:0002438	acute inflammatory response to antigenic stimulus	2/896	24/18722	0.3200225750856	0.505168246098148	HLA-E/BTK	2
GO:0003181	atrioventricular valve morphogenesis	2/896	24/18722	0.3200225750856	0.505168246098148	TGFBR2/MDM4	2
GO:0010288	response to lead ion	2/896	24/18722	0.3200225750856	0.505168246098148	PTGS2/PLSCR1	2
GO:0016048	detection of temperature stimulus	2/896	24/18722	0.3200225750856	0.505168246098148	ARRB2/CXCR4	2
GO:0016486	peptide hormone processing	2/896	24/18722	0.3200225750856	0.505168246098148	CTSZ/ATP6AP2	2
GO:0021697	cerebellar cortex formation	2/896	24/18722	0.3200225750856	0.505168246098148	AGTPBP1/MTPN	2
GO:0021801	cerebral cortex radial glia-guided migration	2/896	24/18722	0.3200225750856	0.505168246098148	SUN2/MBOAT7	2
GO:0022030	telencephalon glial cell migration	2/896	24/18722	0.3200225750856	0.505168246098148	SUN2/MBOAT7	2
GO:0030810	positive regulation of nucleotide biosynthetic process	2/896	24/18722	0.3200225750856	0.505168246098148	TMSB4X/STAT3	2
GO:0031639	plasminogen activation	2/896	24/18722	0.3200225750856	0.505168246098148	CTSZ/PGK1	2
GO:0032528	microvillus organization	2/896	24/18722	0.3200225750856	0.505168246098148	FXYD5/TWF2	2
GO:0044321	response to leptin	2/896	24/18722	0.3200225750856	0.505168246098148	STAT3/PTEN	2
GO:0048641	regulation of skeletal muscle tissue development	2/896	24/18722	0.3200225750856	0.505168246098148	MEF2C/TGFB1	2
GO:0051905	establishment of pigment granule localization	2/896	24/18722	0.3200225750856	0.505168246098148	RAB27A/BLOC1S6	2
GO:0060479	lung cell differentiation	2/896	24/18722	0.3200225750856	0.505168246098148	KLF2/CREB1	2
GO:0070841	inclusion body assembly	2/896	24/18722	0.3200225750856	0.505168246098148	SORL1/HSPA1A	2
GO:0070935	3'-UTR-mediated mRNA stabilization	2/896	24/18722	0.3200225750856	0.505168246098148	ZFP36/MYD88	2
GO:1900373	positive regulation of purine nucleotide biosynthetic process	2/896	24/18722	0.3200225750856	0.505168246098148	TMSB4X/STAT3	2
GO:1903861	positive regulation of dendrite extension	2/896	24/18722	0.3200225750856	0.505168246098148	CXCR4/ITSN2	2
GO:0007006	mitochondrial membrane organization	7/896	116/18722	0.320040255891828	0.505168246098148	BID/HSPA1A/CHCHD10/BNIP3L/STAT3/OXA1L/DYNLT1	7
GO:0006081	cellular aldehyde metabolic process	4/896	60/18722	0.323178473086198	0.509812325908801	CYP1B1/TKT/ALDH1A1/TALDO1	4
GO:0061951	establishment of protein localization to plasma membrane	4/896	60/18722	0.323178473086198	0.509812325908801	VAMP5/RILPL2/CSK/RAB10	4
GO:0006665	sphingolipid metabolic process	9/896	155/18722	0.324438001284267	0.511488949584562	PSAP/PPT1/HACD4/SPTLC2/NAAA/ELOVL5/ST8SIA4/ASAH1/NAGA	9
GO:0051147	regulation of muscle cell differentiation	9/896	155/18722	0.324438001284267	0.511488949584562	RGS2/SOD2/ARRB2/MEF2C/TGFB1/G6PD/PAK1/PIAS1/YBX1	9
GO:0000413	protein peptidyl-prolyl isomerization	3/896	42/18722	0.326043151232677	0.512311308024518	FKBP5/FKBP1A/FKBP15	3
GO:0014003	oligodendrocyte development	3/896	42/18722	0.326043151232677	0.512311308024518	LYN/TLR2/PTEN	3
GO:0019432	triglyceride biosynthetic process	3/896	42/18722	0.326043151232677	0.512311308024518	LPGAT1/ACSL1/ACSL4	3
GO:0021795	cerebral cortex cell migration	3/896	42/18722	0.326043151232677	0.512311308024518	RHOA/SUN2/MBOAT7	3
GO:0030574	collagen catabolic process	3/896	42/18722	0.326043151232677	0.512311308024518	CTSS/CST3/CTSB	3
GO:0030808	regulation of nucleotide biosynthetic process	3/896	42/18722	0.326043151232677	0.512311308024518	TMSB4X/PDK4/STAT3	3
GO:0032467	positive regulation of cytokinesis	3/896	42/18722	0.326043151232677	0.512311308024518	RHOA/CDC42/NUP62	3
GO:0035019	somatic stem cell population maintenance	3/896	42/18722	0.326043151232677	0.512311308024518	ZFP36L2/SPI1/KLF10	3
GO:0045214	sarcomere organization	3/896	42/18722	0.326043151232677	0.512311308024518	AKAP13/PRKAR1A/PLEC	3
GO:1903432	regulation of TORC1 signaling	3/896	42/18722	0.326043151232677	0.512311308024518	C9orf72/ATM/WAC	3
GO:1904037	positive regulation of epithelial cell apoptotic process	3/896	42/18722	0.326043151232677	0.512311308024518	ARRB2/ITGA4/JAK2	3
GO:0000245	spliceosomal complex assembly	5/896	79/18722	0.327214892469511	0.51384198542691	CELF2/SETX/SCAF11/SF3B1/CELF1	5
GO:0006023	aminoglycan biosynthetic process	5/896	79/18722	0.327214892469511	0.51384198542691	IL1B/TGFB1/CSGALNACT2/DSE/NFKB1	5
GO:0061337	cardiac conduction	6/896	98/18722	0.328299699363273	0.515389899302258	FLNA/SLC8A1/KCNE3/CALM2/MEF2A/PRKACA	6
GO:0022900	electron transport chain	10/896	175/18722	0.328437565810383	0.515450748273929	CYBB/CYBA/NCF1/NCF2/ALDH2/SCO2/BID/NQO2/ME2/PLEC	10
GO:0060560	developmental growth involved in morphogenesis	13/896	234/18722	0.330397286659392	0.518369920939818	ITGA4/IQGAP1/CXCR4/ARHGAP4/DPYSL2/NIN/C9orf72/SHTN1/PAK1/TWF2/ITSN2/DBNL/TGFBR2	13
GO:0050684	regulation of mRNA processing	8/896	137/18722	0.333611618114356	0.523255134442932	MBNL1/CELF2/ZFP36L1/DDX5/ZBTB7A/HNRNPU/QKI/CELF1	8
GO:0043966	histone H3 acetylation	4/896	61/18722	0.334162399880515	0.523487542704386	SPI1/TAF10/EP300/KMT2A	4
GO:0050994	regulation of lipid catabolic process	4/896	61/18722	0.334162399880515	0.523487542704386	IL1B/SORL1/TNF/IRS2	4
GO:0060998	regulation of dendritic spine development	4/896	61/18722	0.334162399880515	0.523487542704386	ACTR2/MEF2C/PTEN/DBNL	4
GO:1904356	regulation of telomere maintenance via telomere lengthening	4/896	61/18722	0.334162399880515	0.523487542704386	MAPK1/ATM/HNRNPU/XRN1	4
GO:1903313	positive regulation of mRNA metabolic process	7/896	118/18722	0.335608293026357	0.525594318587799	ZFP36/ZFP36L2/BTG2/PABPC1/ZFP36L1/ROCK1/CELF1	7
GO:0032204	regulation of telomere maintenance	5/896	80/18722	0.336766312118697	0.52606214417818	MAPK1/ATM/HNRNPU/XRN1/SMG1	5
GO:0051303	establishment of chromosome localization	5/896	80/18722	0.336766312118697	0.52606214417818	ACTR2/ACTR3/HNRNPU/CHMP1B/NUP62	5
GO:0010717	regulation of epithelial to mesenchymal transition	6/896	99/18722	0.336849655641345	0.52606214417818	IL1B/GLIPR2/TGFB1/SDCBP/PTEN/TGFBR2	6
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	2/896	25/18722	0.337828794761608	0.52606214417818	CYBA/RHOA	2
GO:0003094	glomerular filtration	2/896	25/18722	0.337828794761608	0.52606214417818	CYBA/SULF2	2
GO:0006658	phosphatidylserine metabolic process	2/896	25/18722	0.337828794761608	0.52606214417818	PLSCR1/OSBPL8	2
GO:0021846	cell proliferation in forebrain	2/896	25/18722	0.337828794761608	0.52606214417818	NUMB/HOOK3	2
GO:0032400	melanosome localization	2/896	25/18722	0.337828794761608	0.52606214417818	RAB27A/BLOC1S6	2
GO:0033119	negative regulation of RNA splicing	2/896	25/18722	0.337828794761608	0.52606214417818	PTBP3/TMBIM6	2
GO:0033233	regulation of protein sumoylation	2/896	25/18722	0.337828794761608	0.52606214417818	EGR1/PIAS1	2
GO:0045109	intermediate filament organization	2/896	25/18722	0.337828794761608	0.52606214417818	VIM/PLEC	2
GO:0045324	late endosome to vacuole transport	2/896	25/18722	0.337828794761608	0.52606214417818	TMEM50A/CHMP1B	2
GO:0048596	embryonic camera-type eye morphogenesis	2/896	25/18722	0.337828794761608	0.52606214417818	HIPK1/SP3	2
GO:0050951	sensory perception of temperature stimulus	2/896	25/18722	0.337828794761608	0.52606214417818	ARRB2/CXCR4	2
GO:0051450	myoblast proliferation	2/896	25/18722	0.337828794761608	0.52606214417818	GPX1/MALAT1	2
GO:0060706	cell differentiation involved in embryonic placenta development	2/896	25/18722	0.337828794761608	0.52606214417818	SOCS3/STK4	2
GO:0086013	membrane repolarization during cardiac muscle cell action potential	2/896	25/18722	0.337828794761608	0.52606214417818	FLNA/KCNE3	2
GO:1904754	positive regulation of vascular associated smooth muscle cell migration	2/896	25/18722	0.337828794761608	0.52606214417818	IQGAP1/PAK1	2
GO:2000316	regulation of T-helper 17 type immune response	2/896	25/18722	0.337828794761608	0.52606214417818	NFKBIZ/CLEC7A	2
GO:0006458	'de novo' protein folding	3/896	43/18722	0.339330154408609	0.526980033765057	CD74/HSPA1A/FKBP1A	3
GO:0034661	ncRNA catabolic process	3/896	43/18722	0.339330154408609	0.526980033765057	NUDT16/DICER1/XRN1	3
GO:0045981	positive regulation of nucleotide metabolic process	3/896	43/18722	0.339330154408609	0.526980033765057	TMSB4X/STAT3/HIF1A	3
GO:0060443	mammary gland morphogenesis	3/896	43/18722	0.339330154408609	0.526980033765057	CSF1R/STAT6/TGFBR2	3
GO:0090278	negative regulation of peptide hormone secretion	3/896	43/18722	0.339330154408609	0.526980033765057	UCP2/MIDN/PPP3CA	3
GO:0098815	modulation of excitatory postsynaptic potential	3/896	43/18722	0.339330154408609	0.526980033765057	LRRK2/PTK2B/PTEN	3
GO:0120178	steroid hormone biosynthetic process	3/896	43/18722	0.339330154408609	0.526980033765057	TSPO/EGR1/HSD17B11	3
GO:1900544	positive regulation of purine nucleotide metabolic process	3/896	43/18722	0.339330154408609	0.526980033765057	TMSB4X/STAT3/HIF1A	3
GO:1903793	positive regulation of anion transport	3/896	43/18722	0.339330154408609	0.526980033765057	IL1B/CEBPB/PTAFR	3
GO:0051302	regulation of cell division	10/896	177/18722	0.341154039806968	0.529654376428669	IL1B/TXNIP/EVI2B/TGFB1/RHOA/CALM2/CDC42/YBX1/NUP62/CIB1	10
GO:1903522	regulation of blood circulation	14/896	256/18722	0.342664616284226	0.531840844313416	RGS2/FLNA/PTGS2/CELF2/JAK2/HBEGF/SLC8A1/KCNE3/RHOA/TBXAS1/GCH1/CALM2/MEF2A/PRKACA	14
GO:0018393	internal peptidyl-lysine acetylation	9/896	158/18722	0.344685566326123	0.534817908849095	IL1B/SPI1/MSL3/PHF20L1/TAF10/CREBBP/EP300/KMT2A/EPC1	9
GO:0009311	oligosaccharide metabolic process	4/896	62/18722	0.345162269706487	0.535006110829626	FBP1/ST8SIA4/CTBS/NAGA	4
GO:0031124	mRNA 3'-end processing	4/896	62/18722	0.345162269706487	0.535006110829626	PABPC1/ZFP36L1/PCF11/LSM10	4
GO:1903078	positive regulation of protein localization to plasma membrane	4/896	62/18722	0.345162269706487	0.535006110829626	TNF/RHOG/PRNP/CIB1	4
GO:0019218	regulation of steroid metabolic process	6/896	100/18722	0.345424056944027	0.535006110829626	TSPO/EGR1/TNF/ASAH1/LAMTOR1/NFKB1	6
GO:0051588	regulation of neurotransmitter transport	6/896	100/18722	0.345424056944027	0.535006110829626	LRRK2/MEF2C/PRKCB/MCTP1/RAP1A/RAP1B	6
GO:0060079	excitatory postsynaptic potential	6/896	100/18722	0.345424056944027	0.535006110829626	LRRK2/ARRB2/MEF2C/PTK2B/PTEN/PPP3CA	6
GO:0051149	positive regulation of muscle cell differentiation	5/896	81/18722	0.346339898089972	0.536264903234875	SOD2/ARRB2/MEF2C/TGFB1/PIAS1	5
GO:0019318	hexose metabolic process	13/896	237/18722	0.346911289096081	0.536989766246642	OAS1/TNF/SERP1/FBP1/MIDN/PDK4/G6PD/PGK1/ATF3/ADPGK/IRS2/PTPN2/EP300	13
GO:0042445	hormone metabolic process	12/896	218/18722	0.351276586810272	0.543424040419031	TSPO/EGR1/CYP1B1/HSD17B11/CTSZ/SULT1A1/SCPEP1/ALDH1A1/CTSB/HIF1A/ATP6AP2/NFKB1	12
GO:0048675	axon extension	7/896	120/18722	0.351276989788268	0.543424040419031	ARHGAP4/DPYSL2/C9orf72/SHTN1/PAK1/TWF2/DBNL	7
GO:0008542	visual learning	3/896	44/18722	0.35259909664705	0.544821123488208	HIF1A/PIAS1/CREB1	3
GO:0032881	regulation of polysaccharide metabolic process	3/896	44/18722	0.35259909664705	0.544821123488208	TGFB1/IRS2/NFKB1	3
GO:0044058	regulation of digestive system process	3/896	44/18722	0.35259909664705	0.544821123488208	TYMP/SGK1/WNK1	3
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	3/896	44/18722	0.35259909664705	0.544821123488208	MSN/RHOA/CDC42	3
GO:0006941	striated muscle contraction	10/896	179/18722	0.353952972720611	0.545399348201952	RGS2/FLNA/NR4A1/RCSD1/SLC8A1/KCNE3/CXCR4/CALM2/PRKACA/EEF2	10
GO:0001655	urogenital system development	18/896	338/18722	0.354461080369987	0.545399348201952	CRIP1/LRRK2/EGR1/STAT1/PSAP/MEF2C/PECAM1/IQGAP1/CTSH/NOTCH2/SULF2/RHOA/IL6R/APAF1/CNTRL/CFLAR/PTEN/NIPBL	18
GO:0001963	synaptic transmission, dopaminergic	2/896	26/18722	0.355490057759011	0.545399348201952	PTGS2/ARRB2	2
GO:0002092	positive regulation of receptor internalization	2/896	26/18722	0.355490057759011	0.545399348201952	ARRB2/SYK	2
GO:0006760	folic acid-containing compound metabolic process	2/896	26/18722	0.355490057759011	0.545399348201952	GCH1/MTHFD2	2
GO:0008535	respiratory chain complex IV assembly	2/896	26/18722	0.355490057759011	0.545399348201952	SCO2/OXA1L	2
GO:0010875	positive regulation of cholesterol efflux	2/896	26/18722	0.355490057759011	0.545399348201952	NFKBIA/RXRA	2
GO:0014829	vascular associated smooth muscle contraction	2/896	26/18722	0.355490057759011	0.545399348201952	SLC8A1/RHOA	2
GO:0033522	histone H2A ubiquitination	2/896	26/18722	0.355490057759011	0.545399348201952	DTX3L/TRIP12	2
GO:0034063	stress granule assembly	2/896	26/18722	0.355490057759011	0.545399348201952	C9orf72/DDX3X	2
GO:0034643	establishment of mitochondrion localization, microtubule-mediated	2/896	26/18722	0.355490057759011	0.545399348201952	AGTPBP1/HIF1A	2
GO:0042634	regulation of hair cycle	2/896	26/18722	0.355490057759011	0.545399348201952	TNF/NIPBL	2
GO:0043094	cellular metabolic compound salvage	2/896	26/18722	0.355490057759011	0.545399348201952	CDA/UPP1	2
GO:0043501	skeletal muscle adaptation	2/896	26/18722	0.355490057759011	0.545399348201952	CFLAR/PPP3CA	2
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	2/896	26/18722	0.355490057759011	0.545399348201952	HLA-E/HLA-F	2
GO:0047497	mitochondrion transport along microtubule	2/896	26/18722	0.355490057759011	0.545399348201952	AGTPBP1/HIF1A	2
GO:0051875	pigment granule localization	2/896	26/18722	0.355490057759011	0.545399348201952	RAB27A/BLOC1S6	2
GO:0060352	cell adhesion molecule production	2/896	26/18722	0.355490057759011	0.545399348201952	IL1B/CXCL8	2
GO:0070977	bone maturation	2/896	26/18722	0.355490057759011	0.545399348201952	SNX10/RHOA	2
GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	2/896	26/18722	0.355490057759011	0.545399348201952	GNAI2/AKAP13	2
GO:0097205	renal filtration	2/896	26/18722	0.355490057759011	0.545399348201952	CYBA/SULF2	2
GO:1901071	glucosamine-containing compound metabolic process	2/896	26/18722	0.355490057759011	0.545399348201952	NAGK/CTBS	2
GO:1904353	regulation of telomere capping	2/896	26/18722	0.355490057759011	0.545399348201952	MAPK1/ATM	2
GO:1904861	excitatory synapse assembly	2/896	26/18722	0.355490057759011	0.545399348201952	PTEN/PLXNB2	2
GO:0016575	histone deacetylation	5/896	82/18722	0.355929444962424	0.545751486807066	LRRK2/BCL6/NIPBL/MSL3/KDM5A	5
GO:0050000	chromosome localization	5/896	82/18722	0.355929444962424	0.545751486807066	ACTR2/ACTR3/HNRNPU/CHMP1B/NUP62	5
GO:0001947	heart looping	4/896	63/18722	0.356168893680734	0.545796822638038	MEF2C/NOTCH2/HIF1A/TGFBR2	4
GO:0099601	regulation of neurotransmitter receptor activity	4/896	63/18722	0.356168893680734	0.545796822638038	MEF2C/IFNGR2/CCR2/PTK2B	4
GO:0006475	internal protein amino acid acetylation	9/896	160/18722	0.358289445138784	0.548884655130138	IL1B/SPI1/MSL3/PHF20L1/TAF10/CREBBP/EP300/KMT2A/EPC1	9
GO:0001838	embryonic epithelial tube formation	7/896	121/18722	0.359140427073957	0.549864398354917	VASP/TGFB1/STK4/PRKACA/PFN1/HIF1A/PLXNB2	7
GO:0045931	positive regulation of mitotic cell cycle	7/896	121/18722	0.359140427073957	0.549864398354917	AIF1/EIF4EBP1/KMT2E/RB1/LSM10/ADAM17/DDX3X	7
GO:0072522	purine-containing compound biosynthetic process	11/896	200/18722	0.361863440606892	0.553870439845922	TMSB4X/PPT1/TGFB1/ACSL1/PDK4/PRKAG2/ELOVL5/ATP6V1A/STAT3/ADCY7/ACSL4	11
GO:0062014	negative regulation of small molecule metabolic process	6/896	102/18722	0.362628156889141	0.554714424700124	PLEK/CDA/FBP1/STAT3/EP300/NFKB1	6
GO:1902749	regulation of cell cycle G2/M phase transition	6/896	102/18722	0.362628156889141	0.554714424700124	TAOK3/CDKN1A/ATM/NABP1/FOXN3/TAOK1	6
GO:0031503	protein-containing complex localization	12/896	220/18722	0.362894034124083	0.554957915754	TYROBP/TNFAIP2/NUP214/NUMB/HHEX/RALB/RAP1A/ADAM10/ATM/HNRNPU/SMG1/STX7	12
GO:0032886	regulation of microtubule-based process	13/896	240/18722	0.363575264276069	0.555836257936459	RHOA/HSPA1A/NIN/PAK1/DIAPH1/ROCK1/CYLD/BICD2/HNRNPU/TAOK1/CHMP1B/NUP62/CIB1	13
GO:0051899	membrane depolarization	5/896	83/18722	0.365528872117983	0.558142961816287	TSPO/LRRK2/CASP1/SLC8A1/JUN	5
GO:0003009	skeletal muscle contraction	3/896	45/18722	0.365835292603677	0.558142961816287	NR4A1/RCSD1/EEF2	3
GO:0030850	prostate gland development	3/896	45/18722	0.365835292603677	0.558142961816287	CRIP1/PSAP/PTEN	3
GO:0035272	exocrine system development	3/896	45/18722	0.365835292603677	0.558142961816287	TGFB1/TNF/CDC42	3
GO:0035987	endodermal cell differentiation	3/896	45/18722	0.365835292603677	0.558142961816287	ITGB2/ITGA4/ITGA5	3
GO:0046189	phenol-containing compound biosynthetic process	3/896	45/18722	0.365835292603677	0.558142961816287	ZEB2/NR4A2/GCH1	3
GO:1901985	positive regulation of protein acetylation	3/896	45/18722	0.365835292603677	0.558142961816287	IL1B/TAOK1/DDX3X	3
GO:0006749	glutathione metabolic process	4/896	64/18722	0.367173364582603	0.559363992148248	GPX1/G6PD/CLIC1/GSTK1	4
GO:0006940	regulation of smooth muscle contraction	4/896	64/18722	0.367173364582603	0.559363992148248	RGS2/PTGS2/RHOA/PTAFR	4
GO:0046854	phosphatidylinositol phosphate biosynthetic process	4/896	64/18722	0.367173364582603	0.559363992148248	SOCS3/ATM/PIP4K2A/SMG1	4
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	4/896	64/18722	0.367173364582603	0.559363992148248	HLA-DRB1/UCP2/NADK/HIF1A	4
GO:0098930	axonal transport	4/896	64/18722	0.367173364582603	0.559363992148248	BLOC1S1/AGTPBP1/HIF1A/BLOC1S6	4
GO:0050773	regulation of dendrite development	6/896	103/18722	0.371248994562655	0.565407326711675	ACTR2/IQGAP1/RHOA/PREX1/DBNL/PPP3CA	6
GO:0021953	central nervous system neuron differentiation	9/896	162/18722	0.371956835562078	0.565888628715073	B2M/BTG2/NR4A2/ZSWIM6/AGTPBP1/NIN/MTPN/PTEN/MYCBP2	9
GO:0003171	atrioventricular valve development	2/896	27/18722	0.372979469185785	0.565888628715073	TGFBR2/MDM4	2
GO:0007026	negative regulation of microtubule depolymerization	2/896	27/18722	0.372979469185785	0.565888628715073	TAOK1/CIB1	2
GO:0007263	nitric oxide mediated signal transduction	2/896	27/18722	0.372979469185785	0.565888628715073	FPR1/CD36	2
GO:0007628	adult walking behavior	2/896	27/18722	0.372979469185785	0.565888628715073	ARRB2/AGTPBP1	2
GO:0010586	miRNA metabolic process	2/896	27/18722	0.372979469185785	0.565888628715073	DICER1/NFKB1	2
GO:0014850	response to muscle activity	2/896	27/18722	0.372979469185785	0.565888628715073	METRNL/HIF1A	2
GO:0046174	polyol catabolic process	2/896	27/18722	0.372979469185785	0.565888628715073	PTEN/NUDT3	2
GO:1902883	negative regulation of response to oxidative stress	2/896	27/18722	0.372979469185785	0.565888628715073	LRRK2/MCTP1	2
GO:1903421	regulation of synaptic vesicle recycling	2/896	27/18722	0.372979469185785	0.565888628715073	LRRK2/ROCK1	2
GO:1903859	regulation of dendrite extension	2/896	27/18722	0.372979469185785	0.565888628715073	CXCR4/ITSN2	2
GO:1904357	negative regulation of telomere maintenance via telomere lengthening	2/896	27/18722	0.372979469185785	0.565888628715073	HNRNPU/XRN1	2
GO:2000463	positive regulation of excitatory postsynaptic potential	2/896	27/18722	0.372979469185785	0.565888628715073	PTK2B/PTEN	2
GO:0003231	cardiac ventricle development	7/896	123/18722	0.374908454583316	0.568649423239378	MEF2C/TGFB1/CNTRL/FKBP1A/HIF1A/TGFBR2/MDM4	7
GO:0032370	positive regulation of lipid transport	5/896	84/18722	0.375132230363028	0.568657164126525	IL1B/NFKBIA/RETN/ACSL1/RXRA	5
GO:0042440	pigment metabolic process	5/896	84/18722	0.375132230363028	0.568657164126525	TSPO/ZEB2/BLVRB/BLVRA/HMOX1	5
GO:0015909	long-chain fatty acid transport	4/896	65/18722	0.37816706439996	0.572756814776993	CD36/SYK/ACSL1/IRS2	4
GO:0060389	pathway-restricted SMAD protein phosphorylation	4/896	65/18722	0.37816706439996	0.572756814776993	USP15/TGFB1/SDCBP/TGFBR2	4
GO:0072577	endothelial cell apoptotic process	4/896	65/18722	0.37816706439996	0.572756814776993	TNFAIP3/ITGA4/TNF/HIPK1	4
GO:0006195	purine nucleotide catabolic process	3/896	46/18722	0.379024830413728	0.57284905617474	SAMHD1/NUDT16/NUDT3	3
GO:0031057	negative regulation of histone modification	3/896	46/18722	0.379024830413728	0.57284905617474	SPI1/KDM5A/TRIP12	3
GO:0043462	regulation of ATPase activity	3/896	46/18722	0.379024830413728	0.57284905617474	PFN1/OXA1L/VMA21	3
GO:0043616	keratinocyte proliferation	3/896	46/18722	0.379024830413728	0.57284905617474	ZFP36/NOTCH2/ZFP36L1	3
GO:0072599	establishment of protein localization to endoplasmic reticulum	3/896	46/18722	0.379024830413728	0.57284905617474	RAB10/SPCS3/HERPUD1	3
GO:0006892	post-Golgi vesicle-mediated transport	6/896	104/18722	0.379876564822087	0.57284905617474	LAPTM5/VAMP5/VPS13C/SORL1/CSK/RAB10	6
GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	6/896	104/18722	0.379876564822087	0.57284905617474	FPR1/C5AR1/CX3CR1/LPAR6/GPR65/GNB1	6
GO:0022600	digestive system process	6/896	104/18722	0.379876564822087	0.57284905617474	TYMP/CD36/SNX10/TLR4/SGK1/WNK1	6
GO:0009142	nucleoside triphosphate biosynthetic process	5/896	85/18722	0.384733707920357	0.57284905617474	TMSB4X/TGFB1/PRKAG2/ATP6V1A/STAT3	5
GO:0097006	regulation of plasma lipoprotein particle levels	5/896	85/18722	0.384733707920357	0.57284905617474	CD36/CSK/PRKACA/LIPA/HMOX1	5
GO:0097194	execution phase of apoptosis	5/896	85/18722	0.384733707920357	0.57284905617474	PLSCR1/PAK2/CFLAR/DICER1/TAOK1	5
GO:0001553	luteinization	1/896	10/18722	0.387700187989826	0.57284905617474	RETN	1
GO:0001865	NK T cell differentiation	1/896	10/18722	0.387700187989826	0.57284905617474	TGFBR2	1
GO:0002084	protein depalmitoylation	1/896	10/18722	0.387700187989826	0.57284905617474	PPT1	1
GO:0003056	regulation of vascular associated smooth muscle contraction	1/896	10/18722	0.387700187989826	0.57284905617474	RHOA	1
GO:0005984	disaccharide metabolic process	1/896	10/18722	0.387700187989826	0.57284905617474	FBP1	1
GO:0006171	cAMP biosynthetic process	1/896	10/18722	0.387700187989826	0.57284905617474	ADCY7	1
GO:0006222	UMP biosynthetic process	1/896	10/18722	0.387700187989826	0.57284905617474	UPP1	1
GO:0006547	histidine metabolic process	1/896	10/18722	0.387700187989826	0.57284905617474	HNMT	1
GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	1/896	10/18722	0.387700187989826	0.57284905617474	GNB1	1
GO:0009174	pyrimidine ribonucleoside monophosphate biosynthetic process	1/896	10/18722	0.387700187989826	0.57284905617474	UPP1	1
GO:0009396	folic acid-containing compound biosynthetic process	1/896	10/18722	0.387700187989826	0.57284905617474	GCH1	1
GO:0009750	response to fructose	1/896	10/18722	0.387700187989826	0.57284905617474	PTGS2	1
GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation	1/896	10/18722	0.387700187989826	0.57284905617474	PPP1R15B	1
GO:0014041	regulation of neuron maturation	1/896	10/18722	0.387700187989826	0.57284905617474	LRRK2	1
GO:0016139	glycoside catabolic process	1/896	10/18722	0.387700187989826	0.57284905617474	NAGA	1
GO:0021903	rostrocaudal neural tube patterning	1/896	10/18722	0.387700187989826	0.57284905617474	ATP6AP2	1
GO:0021932	hindbrain radial glia guided cell migration	1/896	10/18722	0.387700187989826	0.57284905617474	FLNA	1
GO:0030388	fructose 1,6-bisphosphate metabolic process	1/896	10/18722	0.387700187989826	0.57284905617474	FBP1	1
GO:0031642	negative regulation of myelination	1/896	10/18722	0.387700187989826	0.57284905617474	PTEN	1
GO:0031915	positive regulation of synaptic plasticity	1/896	10/18722	0.387700187989826	0.57284905617474	PTGS2	1
GO:0033080	immature T cell proliferation in thymus	1/896	10/18722	0.387700187989826	0.57284905617474	IL1B	1
GO:0033131	regulation of glucokinase activity	1/896	10/18722	0.387700187989826	0.57284905617474	MIDN	1
GO:0034756	regulation of iron ion transport	1/896	10/18722	0.387700187989826	0.57284905617474	B2M	1
GO:0035520	monoubiquitinated protein deubiquitination	1/896	10/18722	0.387700187989826	0.57284905617474	USP15	1
GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	1/896	10/18722	0.387700187989826	0.57284905617474	SULF2	1
GO:0035871	protein K11-linked deubiquitination	1/896	10/18722	0.387700187989826	0.57284905617474	TNFAIP3	1
GO:0035999	tetrahydrofolate interconversion	1/896	10/18722	0.387700187989826	0.57284905617474	MTHFD2	1
GO:0036109	alpha-linolenic acid metabolic process	1/896	10/18722	0.387700187989826	0.57284905617474	ELOVL5	1
GO:0038007	netrin-activated signaling pathway	1/896	10/18722	0.387700187989826	0.57284905617474	SHTN1	1
GO:0040015	negative regulation of multicellular organism growth	1/896	10/18722	0.387700187989826	0.57284905617474	PLAC8	1
GO:0042996	regulation of Golgi to plasma membrane protein transport	1/896	10/18722	0.387700187989826	0.57284905617474	CSK	1
GO:0045835	negative regulation of meiotic nuclear division	1/896	10/18722	0.387700187989826	0.57284905617474	PRKAR1A	1
GO:0045843	negative regulation of striated muscle tissue development	1/896	10/18722	0.387700187989826	0.57284905617474	TGFB1	1
GO:0045898	regulation of RNA polymerase II transcription preinitiation complex assembly	1/896	10/18722	0.387700187989826	0.57284905617474	CREB1	1
GO:0048703	embryonic viscerocranium morphogenesis	1/896	10/18722	0.387700187989826	0.57284905617474	NIPBL	1
GO:0048755	branching morphogenesis of a nerve	1/896	10/18722	0.387700187989826	0.57284905617474	LRRK2	1
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	1/896	10/18722	0.387700187989826	0.57284905617474	CALM2	1
GO:0051351	positive regulation of ligase activity	1/896	10/18722	0.387700187989826	0.57284905617474	TMSB4X	1
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	1/896	10/18722	0.387700187989826	0.57284905617474	UCP2	1
GO:0061299	retina vasculature morphogenesis in camera-type eye	1/896	10/18722	0.387700187989826	0.57284905617474	CYP1B1	1
GO:0070383	DNA cytosine deamination	1/896	10/18722	0.387700187989826	0.57284905617474	APOBEC3A	1
GO:0070544	histone H3-K36 demethylation	1/896	10/18722	0.387700187989826	0.57284905617474	KDM7A	1
GO:0071421	manganese ion transmembrane transport	1/896	10/18722	0.387700187989826	0.57284905617474	SLC11A1	1
GO:0071838	cell proliferation in bone marrow	1/896	10/18722	0.387700187989826	0.57284905617474	MAP3K3	1
GO:0090043	regulation of tubulin deacetylation	1/896	10/18722	0.387700187989826	0.57284905617474	EP300	1
GO:0090209	negative regulation of triglyceride metabolic process	1/896	10/18722	0.387700187989826	0.57284905617474	SORL1	1
GO:0090527	actin filament reorganization	1/896	10/18722	0.387700187989826	0.57284905617474	ARAP1	1
GO:0097105	presynaptic membrane assembly	1/896	10/18722	0.387700187989826	0.57284905617474	PTEN	1
GO:0097250	mitochondrial respirasome assembly	1/896	10/18722	0.387700187989826	0.57284905617474	HIGD2A	1
GO:0097278	complement-dependent cytotoxicity	1/896	10/18722	0.387700187989826	0.57284905617474	RAB27A	1
GO:0099171	presynaptic modulation of chemical synaptic transmission	1/896	10/18722	0.387700187989826	0.57284905617474	PRKCB	1
GO:0099532	synaptic vesicle endosomal processing	1/896	10/18722	0.387700187989826	0.57284905617474	ITSN2	1
GO:0140059	dendrite arborization	1/896	10/18722	0.387700187989826	0.57284905617474	PHACTR1	1
GO:0150172	regulation of phosphatidylcholine metabolic process	1/896	10/18722	0.387700187989826	0.57284905617474	CAPN2	1
GO:1900246	positive regulation of RIG-I signaling pathway	1/896	10/18722	0.387700187989826	0.57284905617474	USP15	1
GO:1901203	positive regulation of extracellular matrix assembly	1/896	10/18722	0.387700187989826	0.57284905617474	TGFB1	1
GO:1901524	regulation of mitophagy	1/896	10/18722	0.387700187989826	0.57284905617474	VPS13C	1
GO:1901978	positive regulation of cell cycle checkpoint	1/896	10/18722	0.387700187989826	0.57284905617474	DYNC1LI1	1
GO:1902023	L-arginine transport	1/896	10/18722	0.387700187989826	0.57284905617474	SLC11A1	1
GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	1/896	10/18722	0.387700187989826	0.57284905617474	PTPN2	1
GO:1904668	positive regulation of ubiquitin protein ligase activity	1/896	10/18722	0.387700187989826	0.57284905617474	PTEN	1
GO:1904779	regulation of protein localization to centrosome	1/896	10/18722	0.387700187989826	0.57284905617474	NUP62	1
GO:1904896	ESCRT complex disassembly	1/896	10/18722	0.387700187989826	0.57284905617474	CHMP1B	1
GO:1904903	ESCRT III complex disassembly	1/896	10/18722	0.387700187989826	0.57284905617474	CHMP1B	1
GO:1905809	negative regulation of synapse organization	1/896	10/18722	0.387700187989826	0.57284905617474	TLR2	1
GO:1905941	positive regulation of gonad development	1/896	10/18722	0.387700187989826	0.57284905617474	RETN	1
GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	1/896	10/18722	0.387700187989826	0.57284905617474	EEF2	1
GO:1990535	neuron projection maintenance	1/896	10/18722	0.387700187989826	0.57284905617474	PRNP	1
GO:2000252	negative regulation of feeding behavior	1/896	10/18722	0.387700187989826	0.57284905617474	RETN	1
GO:2000288	positive regulation of myoblast proliferation	1/896	10/18722	0.387700187989826	0.57284905617474	MALAT1	1
GO:2000425	regulation of apoptotic cell clearance	1/896	10/18722	0.387700187989826	0.57284905617474	CD300LF	1
GO:2000434	regulation of protein neddylation	1/896	10/18722	0.387700187989826	0.57284905617474	HIF1A	1
GO:2000659	regulation of interleukin-1-mediated signaling pathway	1/896	10/18722	0.387700187989826	0.57284905617474	IL1RN	1
GO:2000674	regulation of type B pancreatic cell apoptotic process	1/896	10/18722	0.387700187989826	0.57284905617474	CAST	1
GO:2001223	negative regulation of neuron migration	1/896	10/18722	0.387700187989826	0.57284905617474	STAT3	1
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	4/896	66/18722	0.389141670507843	0.574203692505612	PTPRC/TGFB1/STAT6/BCL6	4
GO:0016444	somatic cell DNA recombination	4/896	66/18722	0.389141670507843	0.574203692505612	PTPRC/TGFB1/STAT6/BCL6	4
GO:0050922	negative regulation of chemotaxis	4/896	66/18722	0.389141670507843	0.574203692505612	AIF1/DUSP1/RIN3/PTPN2	4
GO:0000423	mitophagy	2/896	28/18722	0.39027303461014	0.574203692505612	VPS13C/TOMM7	2
GO:0007064	mitotic sister chromatid cohesion	2/896	28/18722	0.39027303461014	0.574203692505612	RB1/NIPBL	2
GO:0010884	positive regulation of lipid storage	2/896	28/18722	0.39027303461014	0.574203692505612	CD36/NFKB1	2
GO:0019098	reproductive behavior	2/896	28/18722	0.39027303461014	0.574203692505612	PTEN/MBD2	2
GO:0050996	positive regulation of lipid catabolic process	2/896	28/18722	0.39027303461014	0.574203692505612	IL1B/IRS2	2
GO:0060259	regulation of feeding behavior	2/896	28/18722	0.39027303461014	0.574203692505612	RETN/STAT3	2
GO:0080111	DNA demethylation	2/896	28/18722	0.39027303461014	0.574203692505612	APOBEC3A/TET2	2
GO:0086011	membrane repolarization during action potential	2/896	28/18722	0.39027303461014	0.574203692505612	FLNA/KCNE3	2
GO:0090659	walking behavior	2/896	28/18722	0.39027303461014	0.574203692505612	ARRB2/AGTPBP1	2
GO:0099623	regulation of cardiac muscle cell membrane repolarization	2/896	28/18722	0.39027303461014	0.574203692505612	FLNA/KCNE3	2
GO:1903671	negative regulation of sprouting angiogenesis	2/896	28/18722	0.39027303461014	0.574203692505612	KLF2/ALOX5	2
GO:1903779	regulation of cardiac conduction	2/896	28/18722	0.39027303461014	0.574203692505612	SLC8A1/PRKACA	2
GO:0017148	negative regulation of translation	13/896	245/18722	0.391593264077301	0.57598319187388	ZFP36/RGS2/ZFP36L2/BTG2/PABPC1/ZFP36L1/EIF4EBP1/STAT3/ROCK1/YBX1/CELF1/DDX3X/XRN1	13
GO:0016574	histone ubiquitination	3/896	47/18722	0.392154563445309	0.576319831726208	DTX3L/WAC/TRIP12	3
GO:0045747	positive regulation of Notch signaling pathway	3/896	47/18722	0.392154563445309	0.576319831726208	STAT3/TSPAN14/BMP2K	3
GO:0090279	regulation of calcium ion import	3/896	47/18722	0.392154563445309	0.576319831726208	CCL3/FYN/PRNP	3
GO:0071772	response to BMP	9/896	165/18722	0.392538405806142	0.576558104659063	EGR1/USP15/TGFB1/NOTCH2/SORL1/UBE2D1/SKIL/DDX5/UBE2D3	9
GO:0071773	cellular response to BMP stimulus	9/896	165/18722	0.392538405806142	0.576558104659063	EGR1/USP15/TGFB1/NOTCH2/SORL1/UBE2D1/SKIL/DDX5/UBE2D3	9
GO:0099565	chemical synaptic transmission, postsynaptic	6/896	106/18722	0.397134975006134	0.583144834841023	LRRK2/ARRB2/MEF2C/PTK2B/PTEN/PPP3CA	6
GO:0008016	regulation of heart contraction	11/896	206/18722	0.3986985142985	0.585275465104855	RGS2/FLNA/CELF2/JAK2/HBEGF/SLC8A1/KCNE3/GCH1/CALM2/MEF2A/PRKACA	11
GO:0061371	determination of heart left/right asymmetry	4/896	67/18722	0.400089160562899	0.587151163681614	MEF2C/NOTCH2/HIF1A/TGFBR2	4
GO:0098657	import into cell	12/896	227/18722	0.403911643001175	0.592593640408776	RGS2/SLC2A3/CD36/ACTB/ITGA4/IL10RA/SLC8A1/FYN/ACSL1/IRS2/PRNP/WNK1	12
GO:0006111	regulation of gluconeogenesis	3/896	48/18722	0.405212099545354	0.593086620330823	FBP1/PTPN2/EP300	3
GO:0010569	regulation of double-strand break repair via homologous recombination	3/896	48/18722	0.405212099545354	0.593086620330823	ACTR2/WAS/SMCHD1	3
GO:0042149	cellular response to glucose starvation	3/896	48/18722	0.405212099545354	0.593086620330823	IFI16/UPP1/PRKAG2	3
GO:0045005	DNA-dependent DNA replication maintenance of fidelity	3/896	48/18722	0.405212099545354	0.593086620330823	SAMHD1/FAM111A/BOD1L1	3
GO:0120009	intermembrane lipid transfer	3/896	48/18722	0.405212099545354	0.593086620330823	TSPO/NPC2/OSBPL8	3
GO:0048565	digestive tract development	7/896	127/18722	0.406516351875458	0.593086620330823	CXCL8/TNF/CDKN1A/RB1/HIF1A/NIPBL/TGFBR2	7
GO:0009218	pyrimidine ribonucleotide metabolic process	2/896	29/18722	0.407349444564411	0.593086620330823	DPYD/UPP1	2
GO:0010390	histone monoubiquitination	2/896	29/18722	0.407349444564411	0.593086620330823	DTX3L/WAC	2
GO:0021591	ventricular system development	2/896	29/18722	0.407349444564411	0.593086620330823	NUMB/MBOAT7	2
GO:0021772	olfactory bulb development	2/896	29/18722	0.407349444564411	0.593086620330823	LRRK2/AGTPBP1	2
GO:0022011	myelination in peripheral nervous system	2/896	29/18722	0.407349444564411	0.593086620330823	DICER1/PLEC	2
GO:0032292	peripheral nervous system axon ensheathment	2/896	29/18722	0.407349444564411	0.593086620330823	DICER1/PLEC	2
GO:0032366	intracellular sterol transport	2/896	29/18722	0.407349444564411	0.593086620330823	NPC2/PIP4K2A	2
GO:0032367	intracellular cholesterol transport	2/896	29/18722	0.407349444564411	0.593086620330823	NPC2/PIP4K2A	2
GO:0042759	long-chain fatty acid biosynthetic process	2/896	29/18722	0.407349444564411	0.593086620330823	ALOX5/QKI	2
GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	2/896	29/18722	0.407349444564411	0.593086620330823	CCNY/ADAM17	2
GO:0051654	establishment of mitochondrion localization	2/896	29/18722	0.407349444564411	0.593086620330823	AGTPBP1/HIF1A	2
GO:0051873	killing by host of symbiont cells	2/896	29/18722	0.407349444564411	0.593086620330823	TREM1/MYD88	2
GO:0051883	killing of cells in other organism involved in symbiotic interaction	2/896	29/18722	0.407349444564411	0.593086620330823	TREM1/MYD88	2
GO:0071549	cellular response to dexamethasone stimulus	2/896	29/18722	0.407349444564411	0.593086620330823	CFLAR/NR3C1	2
GO:0051148	negative regulation of muscle cell differentiation	4/896	68/18722	0.411001816194612	0.593086620330823	RGS2/G6PD/PAK1/YBX1	4
GO:1902305	regulation of sodium ion transmembrane transport	4/896	68/18722	0.411001816194612	0.593086620330823	FXYD5/GLRX/CHP1/WNK1	4
GO:0006575	cellular modified amino acid metabolic process	10/896	188/18722	0.412169180362173	0.593086620330823	GPX1/PLSCR1/VNN2/GCH1/CTSB/OSBPL8/G6PD/CLIC1/MTHFD2/GSTK1	10
GO:0000070	mitotic sister chromatid segregation	9/896	168/18722	0.41316468367978	0.593086620330823	DUSP1/RB1/NIPBL/ATM/HNRNPU/CHMP1B/NUP62/ZNF207/DYNC1LI1	9
GO:2000241	regulation of reproductive process	9/896	168/18722	0.41316468367978	0.593086620330823	DUSP1/ARHGDIB/TIMP1/RETN/PTAFR/STK4/PRKAR1A/MYH9/CIB1	9
GO:0001843	neural tube closure	5/896	88/18722	0.413470908856668	0.593086620330823	VASP/TGFB1/PRKACA/PFN1/PLXNB2	5
GO:0031110	regulation of microtubule polymerization or depolymerization	5/896	88/18722	0.413470908856668	0.593086620330823	HSPA1A/NIN/PAK1/TAOK1/CIB1	5
GO:0050905	neuromuscular process	8/896	148/18722	0.413949940600784	0.593086620330823	NR4A1/RCSD1/TPP1/GCH1/AGTPBP1/PTEN/MYCBP2/EEF2	8
GO:0001731	formation of translation preinitiation complex	1/896	11/18722	0.417019375225884	0.593086620330823	EIF2S3	1
GO:0001787	natural killer cell proliferation	1/896	11/18722	0.417019375225884	0.593086620330823	HLA-E	1
GO:0001867	complement activation, lectin pathway	1/896	11/18722	0.417019375225884	0.593086620330823	FCN1	1
GO:0002725	negative regulation of T cell cytokine production	1/896	11/18722	0.417019375225884	0.593086620330823	HLA-F	1
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	1/896	11/18722	0.417019375225884	0.593086620330823	PTPN6	1
GO:0003093	regulation of glomerular filtration	1/896	11/18722	0.417019375225884	0.593086620330823	CYBA	1
GO:0003139	secondary heart field specification	1/896	11/18722	0.417019375225884	0.593086620330823	MEF2C	1
GO:0003157	endocardium development	1/896	11/18722	0.417019375225884	0.593086620330823	STK4	1
GO:0006020	inositol metabolic process	1/896	11/18722	0.417019375225884	0.593086620330823	PPIP5K2	1
GO:0006054	N-acetylneuraminate metabolic process	1/896	11/18722	0.417019375225884	0.593086620330823	NAGK	1
GO:0006086	acetyl-CoA biosynthetic process from pyruvate	1/896	11/18722	0.417019375225884	0.593086620330823	PDK4	1
GO:0006568	tryptophan metabolic process	1/896	11/18722	0.417019375225884	0.593086620330823	KYNU	1
GO:0009120	deoxyribonucleoside metabolic process	1/896	11/18722	0.417019375225884	0.593086620330823	DPYD	1
GO:0009313	oligosaccharide catabolic process	1/896	11/18722	0.417019375225884	0.593086620330823	CTBS	1
GO:0010918	positive regulation of mitochondrial membrane potential	1/896	11/18722	0.417019375225884	0.593086620330823	BID	1
GO:0014010	Schwann cell proliferation	1/896	11/18722	0.417019375225884	0.593086620330823	DICER1	1
GO:0021702	cerebellar Purkinje cell differentiation	1/896	11/18722	0.417019375225884	0.593086620330823	AGTPBP1	1
GO:0032000	positive regulation of fatty acid beta-oxidation	1/896	11/18722	0.417019375225884	0.593086620330823	IRS2	1
GO:0032308	positive regulation of prostaglandin secretion	1/896	11/18722	0.417019375225884	0.593086620330823	IL1B	1
GO:0032351	negative regulation of hormone metabolic process	1/896	11/18722	0.417019375225884	0.593086620330823	NFKB1	1
GO:0032610	interleukin-1 alpha production	1/896	11/18722	0.417019375225884	0.593086620330823	CASP1	1
GO:0032650	regulation of interleukin-1 alpha production	1/896	11/18722	0.417019375225884	0.593086620330823	CASP1	1
GO:0032836	glomerular basement membrane development	1/896	11/18722	0.417019375225884	0.593086620330823	SULF2	1
GO:0033033	negative regulation of myeloid cell apoptotic process	1/896	11/18722	0.417019375225884	0.593086620330823	IRF7	1
GO:0033083	regulation of immature T cell proliferation	1/896	11/18722	0.417019375225884	0.593086620330823	IL1B	1
GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	1/896	11/18722	0.417019375225884	0.593086620330823	PAK1	1
GO:0033210	leptin-mediated signaling pathway	1/896	11/18722	0.417019375225884	0.593086620330823	STAT3	1
GO:0033327	Leydig cell differentiation	1/896	11/18722	0.417019375225884	0.593086620330823	MGST1	1
GO:0034770	histone H4-K20 methylation	1/896	11/18722	0.417019375225884	0.593086620330823	ARID4A	1
GO:0034776	response to histamine	1/896	11/18722	0.417019375225884	0.593086620330823	DIAPH1	1
GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	1/896	11/18722	0.417019375225884	0.593086620330823	SEC14L1	1
GO:0042135	neurotransmitter catabolic process	1/896	11/18722	0.417019375225884	0.593086620330823	HNMT	1
GO:0042447	hormone catabolic process	1/896	11/18722	0.417019375225884	0.593086620330823	HSD17B11	1
GO:0044068	modulation by symbiont of host cellular process	1/896	11/18722	0.417019375225884	0.593086620330823	CD4	1
GO:0045161	neuronal ion channel clustering	1/896	11/18722	0.417019375225884	0.593086620330823	SCLT1	1
GO:0048096	chromatin-mediated maintenance of transcription	1/896	11/18722	0.417019375225884	0.593086620330823	ARID1A	1
GO:0048102	autophagic cell death	1/896	11/18722	0.417019375225884	0.593086620330823	LAPTM5	1
GO:0048103	somatic stem cell division	1/896	11/18722	0.417019375225884	0.593086620330823	ZFP36L2	1
GO:0048635	negative regulation of muscle organ development	1/896	11/18722	0.417019375225884	0.593086620330823	TGFB1	1
GO:0048853	forebrain morphogenesis	1/896	11/18722	0.417019375225884	0.593086620330823	PTEN	1
GO:0051081	nuclear membrane disassembly	1/896	11/18722	0.417019375225884	0.593086620330823	PRKCB	1
GO:0051132	NK T cell activation	1/896	11/18722	0.417019375225884	0.593086620330823	CD300A	1
GO:0051561	positive regulation of mitochondrial calcium ion concentration	1/896	11/18722	0.417019375225884	0.593086620330823	MICU1	1
GO:0051673	membrane disruption in other organism	1/896	11/18722	0.417019375225884	0.593086620330823	MPEG1	1
GO:0051798	positive regulation of hair follicle development	1/896	11/18722	0.417019375225884	0.593086620330823	TNF	1
GO:0055015	ventricular cardiac muscle cell development	1/896	11/18722	0.417019375225884	0.593086620330823	MEF2A	1
GO:0060159	regulation of dopamine receptor signaling pathway	1/896	11/18722	0.417019375225884	0.593086620330823	LRRK2	1
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	1/896	11/18722	0.417019375225884	0.593086620330823	CALM2	1
GO:0060433	bronchus development	1/896	11/18722	0.417019375225884	0.593086620330823	TGFBR2	1
GO:0060742	epithelial cell differentiation involved in prostate gland development	1/896	11/18722	0.417019375225884	0.593086620330823	PSAP	1
GO:0061314	Notch signaling involved in heart development	1/896	11/18722	0.417019375225884	0.593086620330823	NOTCH2	1
GO:0061635	regulation of protein complex stability	1/896	11/18722	0.417019375225884	0.593086620330823	TAPBP	1
GO:0070189	kynurenine metabolic process	1/896	11/18722	0.417019375225884	0.593086620330823	KYNU	1
GO:0070243	regulation of thymocyte apoptotic process	1/896	11/18722	0.417019375225884	0.593086620330823	HIF1A	1
GO:0071313	cellular response to caffeine	1/896	11/18722	0.417019375225884	0.593086620330823	SLC8A1	1
GO:0071492	cellular response to UV-A	1/896	11/18722	0.417019375225884	0.593086620330823	TIMP1	1
GO:0075522	IRES-dependent viral translational initiation	1/896	11/18722	0.417019375225884	0.593086620330823	PCBP2	1
GO:0090160	Golgi to lysosome transport	1/896	11/18722	0.417019375225884	0.593086620330823	LAPTM5	1
GO:0090219	negative regulation of lipid kinase activity	1/896	11/18722	0.417019375225884	0.593086620330823	PIP4K2A	1
GO:0097050	type B pancreatic cell apoptotic process	1/896	11/18722	0.417019375225884	0.593086620330823	CAST	1
GO:0097090	presynaptic membrane organization	1/896	11/18722	0.417019375225884	0.593086620330823	PTEN	1
GO:0097396	response to interleukin-17	1/896	11/18722	0.417019375225884	0.593086620330823	IL17RA	1
GO:0097398	cellular response to interleukin-17	1/896	11/18722	0.417019375225884	0.593086620330823	IL17RA	1
GO:0097400	interleukin-17-mediated signaling pathway	1/896	11/18722	0.417019375225884	0.593086620330823	IL17RA	1
GO:0098792	xenophagy	1/896	11/18722	0.417019375225884	0.593086620330823	CALCOCO2	1
GO:0098935	dendritic transport	1/896	11/18722	0.417019375225884	0.593086620330823	HNRNPU	1
GO:0099022	vesicle tethering	1/896	11/18722	0.417019375225884	0.593086620330823	FAM91A1	1
GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	1/896	11/18722	0.417019375225884	0.593086620330823	NUMB	1
GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration	1/896	11/18722	0.417019375225884	0.593086620330823	SLC8A1	1
GO:0099624	atrial cardiac muscle cell membrane repolarization	1/896	11/18722	0.417019375225884	0.593086620330823	FLNA	1
GO:0106072	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	1/896	11/18722	0.417019375225884	0.593086620330823	GNAI2	1
GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	1/896	11/18722	0.417019375225884	0.593086620330823	CHCHD10	1
GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction	1/896	11/18722	0.417019375225884	0.593086620330823	CALM2	1
GO:1901862	negative regulation of muscle tissue development	1/896	11/18722	0.417019375225884	0.593086620330823	TGFB1	1
GO:1902667	regulation of axon guidance	1/896	11/18722	0.417019375225884	0.593086620330823	MYCBP2	1
GO:1902915	negative regulation of protein polyubiquitination	1/896	11/18722	0.417019375225884	0.593086620330823	TRIP12	1
GO:1903299	regulation of hexokinase activity	1/896	11/18722	0.417019375225884	0.593086620330823	MIDN	1
GO:1903423	positive regulation of synaptic vesicle recycling	1/896	11/18722	0.417019375225884	0.593086620330823	LRRK2	1
GO:1903961	positive regulation of anion transmembrane transport	1/896	11/18722	0.417019375225884	0.593086620330823	PTAFR	1
GO:1904181	positive regulation of membrane depolarization	1/896	11/18722	0.417019375225884	0.593086620330823	TSPO	1
GO:1904321	response to forskolin	1/896	11/18722	0.417019375225884	0.593086620330823	AHR	1
GO:1904322	cellular response to forskolin	1/896	11/18722	0.417019375225884	0.593086620330823	AHR	1
GO:2000615	regulation of histone H3-K9 acetylation	1/896	11/18722	0.417019375225884	0.593086620330823	KMT2A	1
GO:2001053	regulation of mesenchymal cell apoptotic process	1/896	11/18722	0.417019375225884	0.593086620330823	HIF1A	1
GO:0006376	mRNA splice site selection	3/896	49/18722	0.418185788109034	0.593771303291042	CELF2/SETX/CELF1	3
GO:0018198	peptidyl-cysteine modification	3/896	49/18722	0.418185788109034	0.593771303291042	S100A9/S100A8/ZDHHC20	3
GO:0035088	establishment or maintenance of apical/basal cell polarity	3/896	49/18722	0.418185788109034	0.593771303291042	MSN/RHOA/CDC42	3
GO:0043457	regulation of cellular respiration	3/896	49/18722	0.418185788109034	0.593771303291042	RHOA/HIF1A/IFNAR1	3
GO:0061245	establishment or maintenance of bipolar cell polarity	3/896	49/18722	0.418185788109034	0.593771303291042	MSN/RHOA/CDC42	3
GO:0072091	regulation of stem cell proliferation	3/896	49/18722	0.418185788109034	0.593771303291042	PTPRC/ZFP36L1/HNRNPU	3
GO:0003143	embryonic heart tube morphogenesis	4/896	69/18722	0.421872225572244	0.598515396945237	MEF2C/NOTCH2/HIF1A/TGFBR2	4
GO:0007004	telomere maintenance via telomerase	4/896	69/18722	0.421872225572244	0.598515396945237	MAPK1/ATM/HNRNPU/XRN1	4
GO:1904377	positive regulation of protein localization to cell periphery	4/896	69/18722	0.421872225572244	0.598515396945237	TNF/RHOG/PRNP/CIB1	4
GO:0060606	tube closure	5/896	89/18722	0.423009670356394	0.599965447374858	VASP/TGFB1/PRKACA/PFN1/PLXNB2	5
GO:0017145	stem cell division	2/896	30/18722	0.424189872995423	0.600329667877333	ZFP36L2/EVI2B	2
GO:0030204	chondroitin sulfate metabolic process	2/896	30/18722	0.424189872995423	0.600329667877333	CSGALNACT2/DSE	2
GO:0031365	N-terminal protein amino acid modification	2/896	30/18722	0.424189872995423	0.600329667877333	CREBBP/EP300	2
GO:0033137	negative regulation of peptidyl-serine phosphorylation	2/896	30/18722	0.424189872995423	0.600329667877333	RASSF2/PTEN	2
GO:0048799	animal organ maturation	2/896	30/18722	0.424189872995423	0.600329667877333	SNX10/RHOA	2
GO:0061311	cell surface receptor signaling pathway involved in heart development	2/896	30/18722	0.424189872995423	0.600329667877333	TGFB1/NOTCH2	2
GO:1903019	negative regulation of glycoprotein metabolic process	2/896	30/18722	0.424189872995423	0.600329667877333	CST3/HBEGF	2
GO:2000648	positive regulation of stem cell proliferation	2/896	30/18722	0.424189872995423	0.600329667877333	PTPRC/HNRNPU	2
GO:0006302	double-strand break repair	13/896	251/18722	0.425434503891615	0.601927327187238	SAMHD1/ACTR2/WAS/PARP9/SETX/SMCHD1/DTX3L/NIPBL/ATM/ZBTB7A/NABP1/TRIP12/CIB1	13
GO:0006220	pyrimidine nucleotide metabolic process	3/896	50/18722	0.431064705274049	0.608899384065814	TYMP/DPYD/UPP1	3
GO:0007080	mitotic metaphase plate congression	3/896	50/18722	0.431064705274049	0.608899384065814	HNRNPU/CHMP1B/NUP62	3
GO:0007632	visual behavior	3/896	50/18722	0.431064705274049	0.608899384065814	HIF1A/PIAS1/CREB1	3
GO:0008089	anterograde axonal transport	3/896	50/18722	0.431064705274049	0.608899384065814	BLOC1S1/AGTPBP1/BLOC1S6	3
GO:0046460	neutral lipid biosynthetic process	3/896	50/18722	0.431064705274049	0.608899384065814	LPGAT1/ACSL1/ACSL4	3
GO:0046463	acylglycerol biosynthetic process	3/896	50/18722	0.431064705274049	0.608899384065814	LPGAT1/ACSL1/ACSL4	3
GO:0061387	regulation of extent of cell growth	6/896	110/18722	0.431550996056795	0.609420779389463	ARHGAP4/DPYSL2/SHTN1/PAK1/TWF2/DBNL	6
GO:0001822	kidney development	15/896	293/18722	0.431954894618962	0.609825571909127	LRRK2/EGR1/STAT1/MEF2C/PECAM1/IQGAP1/CTSH/NOTCH2/SULF2/RHOA/IL6R/APAF1/CNTRL/CFLAR/NIPBL	15
GO:0002028	regulation of sodium ion transport	5/896	90/18722	0.432519721708047	0.610308839974211	FXYD5/SLC8A1/GLRX/CHP1/WNK1	5
GO:0150063	visual system development	19/896	375/18722	0.432531894663515	0.610308839974211	VIM/KLF4/CYP1B1/SCO2/NOTCH2/TCIRG1/ITGAM/PFDN5/AGTPBP1/SKIL/STAT3/HIF1A/NIPBL/GNB1/TGFBR2/XRN2/HIPK1/MAX/SP3	19
GO:0006661	phosphatidylinositol biosynthetic process	7/896	131/18722	0.438050441441504	0.614311887226024	SOCS3/INPP5D/PTEN/MBOAT7/ATM/PIP4K2A/SMG1	7
GO:0001678	cellular glucose homeostasis	9/896	172/18722	0.440638185755752	0.614311887226024	CYBA/LGALS1/HLA-DRB1/UCP2/NADK/PRKACA/HIF1A/IRS2/PPP3CA	9
GO:0002063	chondrocyte development	2/896	31/18722	0.440777788822321	0.614311887226024	SULF2/TGFBR2	2
GO:0002717	positive regulation of natural killer cell mediated immunity	2/896	31/18722	0.440777788822321	0.614311887226024	HLA-E/HLA-F	2
GO:0021988	olfactory lobe development	2/896	31/18722	0.440777788822321	0.614311887226024	LRRK2/AGTPBP1	2
GO:0030201	heparan sulfate proteoglycan metabolic process	2/896	31/18722	0.440777788822321	0.614311887226024	SULF2/DSE	2
GO:0031114	regulation of microtubule depolymerization	2/896	31/18722	0.440777788822321	0.614311887226024	TAOK1/CIB1	2
GO:0032148	activation of protein kinase B activity	2/896	31/18722	0.440777788822321	0.614311887226024	CCDC88A/OSBPL8	2
GO:0035510	DNA dealkylation	2/896	31/18722	0.440777788822321	0.614311887226024	APOBEC3A/TET2	2
GO:0036257	multivesicular body organization	2/896	31/18722	0.440777788822321	0.614311887226024	RAB27A/CHMP1B	2
GO:0042133	neurotransmitter metabolic process	2/896	31/18722	0.440777788822321	0.614311887226024	AGTPBP1/HNMT	2
GO:0051569	regulation of histone H3-K4 methylation	2/896	31/18722	0.440777788822321	0.614311887226024	KMT2E/KMT2A	2
GO:0060045	positive regulation of cardiac muscle cell proliferation	2/896	31/18722	0.440777788822321	0.614311887226024	MEF2C/MAPK1	2
GO:0060795	cell fate commitment involved in formation of primary germ layer	2/896	31/18722	0.440777788822321	0.614311887226024	KLF4/ETS2	2
GO:0070528	protein kinase C signaling	2/896	31/18722	0.440777788822321	0.614311887226024	PLEK/MYADM	2
GO:0097106	postsynaptic density organization	2/896	31/18722	0.440777788822321	0.614311887226024	LILRB2/PTEN	2
GO:0019935	cyclic-nucleotide-mediated signaling	5/896	91/18722	0.441996168763793	0.614311887226024	RGS2/CD36/CAP1/PTK2B/AHR	5
GO:0016125	sterol metabolic process	8/896	152/18722	0.443227012262637	0.614311887226024	CYP1B1/NPC2/APOBR/G6PD/PRKAG2/LIPA/RXRA/LBR	8
GO:0090501	RNA phosphodiester bond hydrolysis	8/896	152/18722	0.443227012262637	0.614311887226024	SAMHD1/RNASET2/RNASE6/NUDT16/DICER1/XRN2/PCF11/XRN1	8
GO:0050795	regulation of behavior	4/896	71/18722	0.443458199083415	0.614311887226024	CCL3/MEF2C/RETN/STAT3	4
GO:0010874	regulation of cholesterol efflux	3/896	51/18722	0.443838637514212	0.614311887226024	NFKBIA/RXRA/LAMTOR1	3
GO:0021872	forebrain generation of neurons	3/896	51/18722	0.443838637514212	0.614311887226024	B2M/RHOA/ZSWIM6	3
GO:0048013	ephrin receptor signaling pathway	3/896	51/18722	0.443838637514212	0.614311887226024	LYN/FYN/PAK1	3
GO:0051293	establishment of spindle localization	3/896	51/18722	0.443838637514212	0.614311887226024	CFL1/MYH9/DYNLT1	3
GO:0001976	nervous system process involved in regulation of systemic arterial blood pressure	1/896	12/18722	0.444936142891835	0.614311887226024	SOD2	1
GO:0002024	diet induced thermogenesis	1/896	12/18722	0.444936142891835	0.614311887226024	SORL1	1
GO:0002674	negative regulation of acute inflammatory response	1/896	12/18722	0.444936142891835	0.614311887226024	NLRP3	1
GO:0003207	cardiac chamber formation	1/896	12/18722	0.444936142891835	0.614311887226024	MEF2C	1
GO:0006703	estrogen biosynthetic process	1/896	12/18722	0.444936142891835	0.614311887226024	HSD17B11	1
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	1/896	12/18722	0.444936142891835	0.614311887226024	PTPN2	1
GO:0014889	muscle atrophy	1/896	12/18722	0.444936142891835	0.614311887226024	CFLAR	1
GO:0016188	synaptic vesicle maturation	1/896	12/18722	0.444936142891835	0.614311887226024	PICALM	1
GO:0016554	cytidine to uridine editing	1/896	12/18722	0.444936142891835	0.614311887226024	APOBEC3A	1
GO:0021670	lateral ventricle development	1/896	12/18722	0.444936142891835	0.614311887226024	NUMB	1
GO:0030157	pancreatic juice secretion	1/896	12/18722	0.444936142891835	0.614311887226024	WNK1	1
GO:0030397	membrane disassembly	1/896	12/18722	0.444936142891835	0.614311887226024	PRKCB	1
GO:0032306	regulation of prostaglandin secretion	1/896	12/18722	0.444936142891835	0.614311887226024	IL1B	1
GO:0032536	regulation of cell projection size	1/896	12/18722	0.444936142891835	0.614311887226024	TWF2	1
GO:0032780	negative regulation of ATPase activity	1/896	12/18722	0.444936142891835	0.614311887226024	OXA1L	1
GO:0033079	immature T cell proliferation	1/896	12/18722	0.444936142891835	0.614311887226024	IL1B	1
GO:0033127	regulation of histone phosphorylation	1/896	12/18722	0.444936142891835	0.614311887226024	IL1B	1
GO:0033182	regulation of histone ubiquitination	1/896	12/18722	0.444936142891835	0.614311887226024	TRIP12	1
GO:0033235	positive regulation of protein sumoylation	1/896	12/18722	0.444936142891835	0.614311887226024	PIAS1	1
GO:0034392	negative regulation of smooth muscle cell apoptotic process	1/896	12/18722	0.444936142891835	0.614311887226024	ARRB2	1
GO:0035112	genitalia morphogenesis	1/896	12/18722	0.444936142891835	0.614311887226024	NIPBL	1
GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	1/896	12/18722	0.444936142891835	0.614311887226024	SYK	1
GO:0038203	TORC2 signaling	1/896	12/18722	0.444936142891835	0.614311887226024	NCKAP1L	1
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	1/896	12/18722	0.444936142891835	0.614311887226024	PHIP	1
GO:0051255	spindle midzone assembly	1/896	12/18722	0.444936142891835	0.614311887226024	CCDC69	1
GO:0051340	regulation of ligase activity	1/896	12/18722	0.444936142891835	0.614311887226024	TMSB4X	1
GO:0051549	positive regulation of keratinocyte migration	1/896	12/18722	0.444936142891835	0.614311887226024	HBEGF	1
GO:0060123	regulation of growth hormone secretion	1/896	12/18722	0.444936142891835	0.614311887226024	SERP1	1
GO:0060134	prepulse inhibition	1/896	12/18722	0.444936142891835	0.614311887226024	PTEN	1
GO:0060453	regulation of gastric acid secretion	1/896	12/18722	0.444936142891835	0.614311887226024	SGK1	1
GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	1/896	12/18722	0.444936142891835	0.614311887226024	PRKACA	1
GO:0061307	cardiac neural crest cell differentiation involved in heart development	1/896	12/18722	0.444936142891835	0.614311887226024	MAPK1	1
GO:0061308	cardiac neural crest cell development involved in heart development	1/896	12/18722	0.444936142891835	0.614311887226024	MAPK1	1
GO:0061620	glycolytic process through glucose-6-phosphate	1/896	12/18722	0.444936142891835	0.614311887226024	ADPGK	1
GO:0070103	regulation of interleukin-6-mediated signaling pathway	1/896	12/18722	0.444936142891835	0.614311887226024	PTPN2	1
GO:0070493	thrombin-activated receptor signaling pathway	1/896	12/18722	0.444936142891835	0.614311887226024	PLEK	1
GO:0071257	cellular response to electrical stimulus	1/896	12/18722	0.444936142891835	0.614311887226024	PTEN	1
GO:0071287	cellular response to manganese ion	1/896	12/18722	0.444936142891835	0.614311887226024	LRRK2	1
GO:0071468	cellular response to acidic pH	1/896	12/18722	0.444936142891835	0.614311887226024	CHP1	1
GO:0071872	cellular response to epinephrine stimulus	1/896	12/18722	0.444936142891835	0.614311887226024	PRKACA	1
GO:0072182	regulation of nephron tubule epithelial cell differentiation	1/896	12/18722	0.444936142891835	0.614311887226024	STAT1	1
GO:0072376	protein activation cascade	1/896	12/18722	0.444936142891835	0.614311887226024	PRCP	1
GO:0072537	fibroblast activation	1/896	12/18722	0.444936142891835	0.614311887226024	IL17RA	1
GO:0072584	caveolin-mediated endocytosis	1/896	12/18722	0.444936142891835	0.614311887226024	MAPK1	1
GO:0090085	regulation of protein deubiquitination	1/896	12/18722	0.444936142891835	0.614311887226024	TANK	1
GO:0090331	negative regulation of platelet aggregation	1/896	12/18722	0.444936142891835	0.614311887226024	SH2B3	1
GO:0090557	establishment of endothelial intestinal barrier	1/896	12/18722	0.444936142891835	0.614311887226024	MYD88	1
GO:0090677	reversible differentiation	1/896	12/18722	0.444936142891835	0.614311887226024	SOD2	1
GO:0097152	mesenchymal cell apoptotic process	1/896	12/18722	0.444936142891835	0.614311887226024	HIF1A	1
GO:1901894	regulation of ATPase-coupled calcium transmembrane transporter activity	1/896	12/18722	0.444936142891835	0.614311887226024	VMP1	1
GO:1903332	regulation of protein folding	1/896	12/18722	0.444936142891835	0.614311887226024	GRN	1
GO:1903599	positive regulation of autophagy of mitochondrion	1/896	12/18722	0.444936142891835	0.614311887226024	HIF1A	1
GO:1905709	negative regulation of membrane permeability	1/896	12/18722	0.444936142891835	0.614311887226024	DYNLT1	1
GO:1990034	calcium ion export across plasma membrane	1/896	12/18722	0.444936142891835	0.614311887226024	CALM2	1
GO:2000009	negative regulation of protein localization to cell surface	1/896	12/18722	0.444936142891835	0.614311887226024	PICALM	1
GO:2000035	regulation of stem cell division	1/896	12/18722	0.444936142891835	0.614311887226024	EVI2B	1
GO:2000628	regulation of miRNA metabolic process	1/896	12/18722	0.444936142891835	0.614311887226024	NFKB1	1
GO:0072175	epithelial tube formation	7/896	132/18722	0.445899707601738	0.615478869224161	VASP/TGFB1/STK4/PRKACA/PFN1/HIF1A/PLXNB2	7
GO:0006694	steroid biosynthetic process	9/896	173/18722	0.447488039887021	0.617507374755212	TSPO/EGR1/HSD17B11/TNF/G6PD/PRKAG2/ASAH1/LBR/NFKB1	9
GO:0072330	monocarboxylic acid biosynthetic process	11/896	214/18722	0.44802831441795	0.618088929254047	IL1B/CD74/PTGS2/HACD4/ALOX5/TBXAS1/LPGAT1/PDK4/PRKAG2/ELOVL5/QKI	11
GO:0120254	olefinic compound metabolic process	8/896	153/18722	0.450518353216936	0.621359309223359	EGR1/PTGS2/CYP1B1/GPX1/ALOX5/TBXAS1/ALDH1A1/ELOVL5	8
GO:0070509	calcium ion import	5/896	92/18722	0.451434280833823	0.622457501223943	CCL3/SLC8A1/FYN/MICU1/PRNP	5
GO:0000271	polysaccharide biosynthetic process	4/896	72/18722	0.454160481132165	0.625718850958513	TGFB1/CSGALNACT2/IRS2/NFKB1	4
GO:0001707	mesoderm formation	4/896	72/18722	0.454160481132165	0.625718850958513	KLF4/PRKACA/PRKAR1A/KDM6B	4
GO:0005977	glycogen metabolic process	4/896	72/18722	0.454160481132165	0.625718850958513	PRKAG2/PYGL/IRS2/RB1CC1	4
GO:0006790	sulfur compound metabolic process	17/896	339/18722	0.456934181818853	0.627771521995584	GPX1/PPT1/SULT1A1/KYNU/ACSL1/CSGALNACT2/PDK4/G6PD/ELOVL5/CLIC1/GNS/ACSL4/GSTK1/FAR1/DSE/SP1/MAT2A	17
GO:0006308	DNA catabolic process	2/896	32/18722	0.457098779811051	0.627771521995584	DICER1/XRN2	2
GO:0010667	negative regulation of cardiac muscle cell apoptotic process	2/896	32/18722	0.457098779811051	0.627771521995584	JAK2/CFLAR	2
GO:0014044	Schwann cell development	2/896	32/18722	0.457098779811051	0.627771521995584	DICER1/PLEC	2
GO:0019934	cGMP-mediated signaling	2/896	32/18722	0.457098779811051	0.627771521995584	CD36/PTK2B	2
GO:0021799	cerebral cortex radially oriented cell migration	2/896	32/18722	0.457098779811051	0.627771521995584	SUN2/MBOAT7	2
GO:0033687	osteoblast proliferation	2/896	32/18722	0.457098779811051	0.627771521995584	JUNB/RHOA	2
GO:0035767	endothelial cell chemotaxis	2/896	32/18722	0.457098779811051	0.627771521995584	TMSB4X/NR4A1	2
GO:0045879	negative regulation of smoothened signaling pathway	2/896	32/18722	0.457098779811051	0.627771521995584	PRKACA/RB1	2
GO:0046856	phosphatidylinositol dephosphorylation	2/896	32/18722	0.457098779811051	0.627771521995584	INPP5D/PTEN	2
GO:0090140	regulation of mitochondrial fission	2/896	32/18722	0.457098779811051	0.627771521995584	LRRK2/STAT2	2
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	2/896	32/18722	0.457098779811051	0.627771521995584	LGALS9/BCL6	2
GO:0008202	steroid metabolic process	16/896	319/18722	0.460065376498916	0.631678992389351	TSPO/EGR1/CYP1B1/NPC2/HSD17B11/SULT1A1/TNF/APOBR/G6PD/PRKAG2/LIPA/RXRA/ASAH1/LBR/LAMTOR1/NFKB1	16
GO:0048880	sensory system development	19/896	381/18722	0.460346431510472	0.631898070806536	VIM/KLF4/CYP1B1/SCO2/NOTCH2/TCIRG1/ITGAM/PFDN5/AGTPBP1/SKIL/STAT3/HIF1A/NIPBL/GNB1/TGFBR2/XRN2/HIPK1/MAX/SP3	19
GO:0033273	response to vitamin	5/896	93/18722	0.460829492394443	0.632394245367678	TSPO/SOD2/PTGS2/KYNU/EEF2	5
GO:0045664	regulation of neuron differentiation	10/896	196/18722	0.463995717067113	0.634013062126058	B2M/LRRK2/MEF2C/RHOA/BCL6/DPYSL2/TIMP2/ROCK1/PTEN/CTDSP1	10
GO:0006073	cellular glucan metabolic process	4/896	73/18722	0.464793951212408	0.634013062126058	PRKAG2/PYGL/IRS2/RB1CC1	4
GO:0035773	insulin secretion involved in cellular response to glucose stimulus	4/896	73/18722	0.464793951212408	0.634013062126058	HLA-DRB1/UCP2/NADK/HIF1A	4
GO:0044042	glucan metabolic process	4/896	73/18722	0.464793951212408	0.634013062126058	PRKAG2/PYGL/IRS2/RB1CC1	4
GO:0051145	smooth muscle cell differentiation	4/896	73/18722	0.464793951212408	0.634013062126058	SOD2/MEF2C/PIAS1/EPC1	4
GO:0099518	vesicle cytoskeletal trafficking	4/896	73/18722	0.464793951212408	0.634013062126058	MYO1F/MYO1G/BLOC1S1/BLOC1S6	4
GO:1904427	positive regulation of calcium ion transmembrane transport	4/896	73/18722	0.464793951212408	0.634013062126058	VMP1/KCNE3/CALM2/G6PD	4
GO:0045165	cell fate commitment	13/896	258/18722	0.464901190689406	0.634013062126058	MCL1/KLF4/MEF2C/NOTCH2/STAT6/RHOA/IL6R/SPN/CDC42/STAT3/KDM6B/RAB10/ETS2	13
GO:0010970	transport along microtubule	8/896	155/18722	0.465051340069522	0.634013062126058	BLOC1S1/AGTPBP1/CDC42/HIF1A/SUN2/BICD2/HNRNPU/BLOC1S6	8
GO:0009416	response to light stimulus	16/896	320/18722	0.465118660154165	0.634013062126058	FOS/DUSP1/CRIP1/CARD16/TIMP1/PTGS2/GPX1/JUND/CDKN1A/POLK/GNAQ/HIF1A/PIAS1/CREBBP/EP300/CREB1	16
GO:0016042	lipid catabolic process	16/896	320/18722	0.465118660154165	0.634013062126058	IL1B/CYP1B1/AOAH/GPCPD1/HSD17B11/PPT1/SORL1/TNF/PLCB2/NAAA/PLBD1/LIPA/ASAH1/DECR1/IRS2/NAGA	16
GO:1901800	positive regulation of proteasomal protein catabolic process	6/896	114/18722	0.465628893398888	0.634013062126058	LRRK2/HSPA1A/TRIB1/GABARAP/PIAS1/HERPUD1	6
GO:0016925	protein sumoylation	3/896	53/18722	0.469034137124104	0.634013062126058	EGR1/IFIH1/PIAS1	3
GO:0071715	icosanoid transport	3/896	53/18722	0.469034137124104	0.634013062126058	IL1B/SYK/SLCO3A1	3
GO:0099172	presynapse organization	3/896	53/18722	0.469034137124104	0.634013062126058	C5AR1/SDCBP/PTEN	3
GO:0001738	morphogenesis of a polarized epithelium	5/896	94/18722	0.470177404359413	0.634013062126058	MSN/ACTB/RHOA/CDC42/RAB10	5
GO:0001778	plasma membrane repair	1/896	13/18722	0.471517501308132	0.634013062126058	MYH9	1
GO:0001973	G protein-coupled adenosine receptor signaling pathway	1/896	13/18722	0.471517501308132	0.634013062126058	GNAI2	1
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	1/896	13/18722	0.471517501308132	0.634013062126058	STAT1	1
GO:0005513	detection of calcium ion	1/896	13/18722	0.471517501308132	0.634013062126058	CALM2	1
GO:0006000	fructose metabolic process	1/896	13/18722	0.471517501308132	0.634013062126058	FBP1	1
GO:0006586	indolalkylamine metabolic process	1/896	13/18722	0.471517501308132	0.634013062126058	KYNU	1
GO:0006995	cellular response to nitrogen starvation	1/896	13/18722	0.471517501308132	0.634013062126058	GABARAP	1
GO:0007567	parturition	1/896	13/18722	0.471517501308132	0.634013062126058	PTAFR	1
GO:0009650	UV protection	1/896	13/18722	0.471517501308132	0.634013062126058	GPX1	1
GO:0010745	negative regulation of macrophage derived foam cell differentiation	1/896	13/18722	0.471517501308132	0.634013062126058	NFKBIA	1
GO:0010755	regulation of plasminogen activation	1/896	13/18722	0.471517501308132	0.634013062126058	CTSZ	1
GO:0010917	negative regulation of mitochondrial membrane potential	1/896	13/18722	0.471517501308132	0.634013062126058	BNIP3L	1
GO:0010958	regulation of amino acid import across plasma membrane	1/896	13/18722	0.471517501308132	0.634013062126058	RGS2	1
GO:0014745	negative regulation of muscle adaptation	1/896	13/18722	0.471517501308132	0.634013062126058	KLF4	1
GO:0015791	polyol transport	1/896	13/18722	0.471517501308132	0.634013062126058	AQP9	1
GO:0015809	arginine transport	1/896	13/18722	0.471517501308132	0.634013062126058	SLC11A1	1
GO:0015816	glycine transport	1/896	13/18722	0.471517501308132	0.634013062126058	RGS2	1
GO:0016078	tRNA catabolic process	1/896	13/18722	0.471517501308132	0.634013062126058	DICER1	1
GO:0019755	one-carbon compound transport	1/896	13/18722	0.471517501308132	0.634013062126058	AQP9	1
GO:0021554	optic nerve development	1/896	13/18722	0.471517501308132	0.634013062126058	TCIRG1	1
GO:0021681	cerebellar granular layer development	1/896	13/18722	0.471517501308132	0.634013062126058	MTPN	1
GO:0021694	cerebellar Purkinje cell layer formation	1/896	13/18722	0.471517501308132	0.634013062126058	AGTPBP1	1
GO:0021819	layer formation in cerebral cortex	1/896	13/18722	0.471517501308132	0.634013062126058	MBOAT7	1
GO:0030836	positive regulation of actin filament depolymerization	1/896	13/18722	0.471517501308132	0.634013062126058	PLEK	1
GO:0032429	regulation of phospholipase A2 activity	1/896	13/18722	0.471517501308132	0.634013062126058	PPT1	1
GO:0032530	regulation of microvillus organization	1/896	13/18722	0.471517501308132	0.634013062126058	TWF2	1
GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway	1/896	13/18722	0.471517501308132	0.634013062126058	PAK1	1
GO:0033262	regulation of nuclear cell cycle DNA replication	1/896	13/18722	0.471517501308132	0.634013062126058	BCL6	1
GO:0034982	mitochondrial protein processing	1/896	13/18722	0.471517501308132	0.634013062126058	LRRK2	1
GO:0035588	G protein-coupled purinergic receptor signaling pathway	1/896	13/18722	0.471517501308132	0.634013062126058	GNAI2	1
GO:0035745	T-helper 2 cell cytokine production	1/896	13/18722	0.471517501308132	0.634013062126058	NLRP3	1
GO:0042538	hyperosmotic salinity response	1/896	13/18722	0.471517501308132	0.634013062126058	MICU1	1
GO:0043562	cellular response to nitrogen levels	1/896	13/18722	0.471517501308132	0.634013062126058	GABARAP	1
GO:0043970	histone H3-K9 acetylation	1/896	13/18722	0.471517501308132	0.634013062126058	KMT2A	1
GO:0044794	positive regulation by host of viral process	1/896	13/18722	0.471517501308132	0.634013062126058	CFL1	1
GO:0048302	regulation of isotype switching to IgG isotypes	1/896	13/18722	0.471517501308132	0.634013062126058	PTPRC	1
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	1/896	13/18722	0.471517501308132	0.634013062126058	CALM2	1
GO:0051481	negative regulation of cytosolic calcium ion concentration	1/896	13/18722	0.471517501308132	0.634013062126058	SLC8A1	1
GO:0051956	negative regulation of amino acid transport	1/896	13/18722	0.471517501308132	0.634013062126058	RGS2	1
GO:0060340	positive regulation of type I interferon-mediated signaling pathway	1/896	13/18722	0.471517501308132	0.634013062126058	IRF7	1
GO:0060347	heart trabecula formation	1/896	13/18722	0.471517501308132	0.634013062126058	FKBP1A	1
GO:0060707	trophoblast giant cell differentiation	1/896	13/18722	0.471517501308132	0.634013062126058	SOCS3	1
GO:0061000	negative regulation of dendritic spine development	1/896	13/18722	0.471517501308132	0.634013062126058	PTEN	1
GO:0061469	regulation of type B pancreatic cell proliferation	1/896	13/18722	0.471517501308132	0.634013062126058	NR4A1	1
GO:0061615	glycolytic process through fructose-6-phosphate	1/896	13/18722	0.471517501308132	0.634013062126058	ADPGK	1
GO:0070234	positive regulation of T cell apoptotic process	1/896	13/18722	0.471517501308132	0.634013062126058	LGALS9	1
GO:0070254	mucus secretion	1/896	13/18722	0.471517501308132	0.634013062126058	CYBA	1
GO:0071027	nuclear RNA surveillance	1/896	13/18722	0.471517501308132	0.634013062126058	XRN1	1
GO:0071028	nuclear mRNA surveillance	1/896	13/18722	0.471517501308132	0.634013062126058	XRN1	1
GO:0106070	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	1/896	13/18722	0.471517501308132	0.634013062126058	GNAI2	1
GO:0110096	cellular response to aldehyde	1/896	13/18722	0.471517501308132	0.634013062126058	ALDH1A1	1
GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response	1/896	13/18722	0.471517501308132	0.634013062126058	PTPN2	1
GO:1900121	negative regulation of receptor binding	1/896	13/18722	0.471517501308132	0.634013062126058	B2M	1
GO:1900452	regulation of long-term synaptic depression	1/896	13/18722	0.471517501308132	0.634013062126058	LILRB2	1
GO:1901096	regulation of autophagosome maturation	1/896	13/18722	0.471517501308132	0.634013062126058	CALCOCO2	1
GO:1901387	positive regulation of voltage-gated calcium channel activity	1/896	13/18722	0.471517501308132	0.634013062126058	KCNE3	1
GO:1902260	negative regulation of delayed rectifier potassium channel activity	1/896	13/18722	0.471517501308132	0.634013062126058	KCNE3	1
GO:1903789	regulation of amino acid transmembrane transport	1/896	13/18722	0.471517501308132	0.634013062126058	RGS2	1
GO:1904995	negative regulation of leukocyte adhesion to vascular endothelial cell	1/896	13/18722	0.471517501308132	0.634013062126058	KLF4	1
GO:1905907	negative regulation of amyloid fibril formation	1/896	13/18722	0.471517501308132	0.634013062126058	PFDN5	1
GO:1905939	regulation of gonad development	1/896	13/18722	0.471517501308132	0.634013062126058	RETN	1
GO:2000551	regulation of T-helper 2 cell cytokine production	1/896	13/18722	0.471517501308132	0.634013062126058	NLRP3	1
GO:0018345	protein palmitoylation	2/896	33/18722	0.47314038802026	0.634554708121035	GLUL/ZDHHC20	2
GO:0021696	cerebellar cortex morphogenesis	2/896	33/18722	0.47314038802026	0.634554708121035	AGTPBP1/MTPN	2
GO:0042558	pteridine-containing compound metabolic process	2/896	33/18722	0.47314038802026	0.634554708121035	GCH1/MTHFD2	2
GO:0048048	embryonic eye morphogenesis	2/896	33/18722	0.47314038802026	0.634554708121035	HIPK1/SP3	2
GO:0048333	mesodermal cell differentiation	2/896	33/18722	0.47314038802026	0.634554708121035	KLF4/KDM6B	2
GO:0050974	detection of mechanical stimulus involved in sensory perception	2/896	33/18722	0.47314038802026	0.634554708121035	CXCR4/FYN	2
GO:0099084	postsynaptic specialization organization	2/896	33/18722	0.47314038802026	0.634554708121035	LILRB2/PTEN	2
GO:1900181	negative regulation of protein localization to nucleus	2/896	33/18722	0.47314038802026	0.634554708121035	CD36/CHP1	2
GO:1901976	regulation of cell cycle checkpoint	2/896	33/18722	0.47314038802026	0.634554708121035	DUSP1/DYNC1LI1	2
GO:1903715	regulation of aerobic respiration	2/896	33/18722	0.47314038802026	0.634554708121035	RHOA/HIF1A	2
GO:0000077	DNA damage checkpoint signaling	6/896	115/18722	0.474068864812812	0.635472207703977	TAOK3/CDKN1A/ATM/FOXN3/TAOK1/WAC	6
GO:1901989	positive regulation of cell cycle phase transition	6/896	115/18722	0.474068864812812	0.635472207703977	AIF1/KMT2E/RB1/LSM10/ADAM17/DDX3X	6
GO:0098739	import across plasma membrane	9/896	177/18722	0.474755382812038	0.636228483897296	RGS2/SLC2A3/CD36/SLC8A1/FYN/ACSL1/IRS2/PRNP/WNK1	9
GO:0003151	outflow tract morphogenesis	4/896	74/18722	0.475352734570909	0.63670089428362	MEF2C/HIF1A/NIPBL/TGFBR2	4
GO:0048332	mesoderm morphogenesis	4/896	74/18722	0.475352734570909	0.63670089428362	KLF4/PRKACA/PRKAR1A/KDM6B	4
GO:0072001	renal system development	15/896	302/18722	0.478995528838107	0.641414970516733	LRRK2/EGR1/STAT1/MEF2C/PECAM1/IQGAP1/CTSH/NOTCH2/SULF2/RHOA/IL6R/APAF1/CNTRL/CFLAR/NIPBL	15
GO:0006942	regulation of striated muscle contraction	5/896	95/18722	0.479473784936519	0.641724949936911	RGS2/NR4A1/SLC8A1/CALM2/PRKACA	5
GO:0045666	positive regulation of neuron differentiation	5/896	95/18722	0.479473784936519	0.641724949936911	MEF2C/RHOA/BCL6/TIMP2/PTEN	5
GO:0048568	embryonic organ development	21/896	427/18722	0.480870233963904	0.64342837325605	JUNB/MAFB/SOCS3/CXCL8/MEF2C/CEBPB/TGFB1/NOTCH2/TNF/SH2B3/ZFP36L1/STK4/GRB2/HIF1A/MAPK1/NIPBL/MBD2/TGFBR2/HIPK1/KMT2A/SP3	21
GO:0035065	regulation of histone acetylation	3/896	54/18722	0.481438663881508	0.64402327439499	IL1B/SPI1/KMT2A	3
GO:0034754	cellular hormone metabolic process	7/896	137/18722	0.484799735305348	0.648019384046034	TSPO/EGR1/CYP1B1/HSD17B11/SULT1A1/SCPEP1/ALDH1A1	7
GO:0055123	digestive system development	7/896	137/18722	0.484799735305348	0.648019384046034	CXCL8/TNF/CDKN1A/RB1/HIF1A/NIPBL/TGFBR2	7
GO:0060048	cardiac muscle contraction	7/896	137/18722	0.484799735305348	0.648019384046034	RGS2/FLNA/SLC8A1/KCNE3/CXCR4/CALM2/PRKACA	7
GO:0006278	RNA-dependent DNA biosynthetic process	4/896	75/18722	0.485831258900974	0.649231340581697	MAPK1/ATM/HNRNPU/XRN1	4
GO:0030510	regulation of BMP signaling pathway	5/896	96/18722	0.488714570091224	0.651537718442292	NOTCH2/SORL1/UBE2D1/SKIL/UBE2D3	5
GO:0002183	cytoplasmic translational initiation	2/896	34/18722	0.488891956116358	0.651537718442292	EIF2S3/EIF3K	2
GO:0032212	positive regulation of telomere maintenance via telomerase	2/896	34/18722	0.488891956116358	0.651537718442292	MAPK1/ATM	2
GO:0048536	spleen development	2/896	34/18722	0.488891956116358	0.651537718442292	PKN1/ADAM17	2
GO:0051085	chaperone cofactor-dependent protein refolding	2/896	34/18722	0.488891956116358	0.651537718442292	CD74/HSPA1A	2
GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	2/896	34/18722	0.488891956116358	0.651537718442292	LPAR6/GPR65	2
GO:0051973	positive regulation of telomerase activity	2/896	34/18722	0.488891956116358	0.651537718442292	KLF4/MAPK1	2
GO:0090075	relaxation of muscle	2/896	34/18722	0.488891956116358	0.651537718442292	RGS2/SLC8A1	2
GO:2000780	negative regulation of double-strand break repair	2/896	34/18722	0.488891956116358	0.651537718442292	SMCHD1/TRIP12	2
GO:0010676	positive regulation of cellular carbohydrate metabolic process	3/896	55/18722	0.493704084148289	0.651537718442292	PTAFR/IRS2/PTPN2	3
GO:0031113	regulation of microtubule polymerization	3/896	55/18722	0.493704084148289	0.651537718442292	HSPA1A/NIN/PAK1	3
GO:0098900	regulation of action potential	3/896	55/18722	0.493704084148289	0.651537718442292	FLNA/CD36/KCNE3	3
GO:0001937	negative regulation of endothelial cell proliferation	4/896	76/18722	0.496224251042265	0.651537718442292	STAT1/MEF2C/TNF/ALOX5	4
GO:0000212	meiotic spindle organization	1/896	14/18722	0.49682726232304	0.651537718442292	MYH9	1
GO:0001921	positive regulation of receptor recycling	1/896	14/18722	0.49682726232304	0.651537718442292	ARAP1	1
GO:0003214	cardiac left ventricle morphogenesis	1/896	14/18722	0.49682726232304	0.651537718442292	TGFBR2	1
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	1/896	14/18722	0.49682726232304	0.651537718442292	TGFBR2	1
GO:0006047	UDP-N-acetylglucosamine metabolic process	1/896	14/18722	0.49682726232304	0.651537718442292	MGAT1	1
GO:0006521	regulation of cellular amino acid metabolic process	1/896	14/18722	0.49682726232304	0.651537718442292	SLC7A7	1
GO:0007100	mitotic centrosome separation	1/896	14/18722	0.49682726232304	0.651537718442292	NUP62	1
GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	1/896	14/18722	0.49682726232304	0.651537718442292	UPP1	1
GO:0010457	centriole-centriole cohesion	1/896	14/18722	0.49682726232304	0.651537718442292	NIN	1
GO:0010838	positive regulation of keratinocyte proliferation	1/896	14/18722	0.49682726232304	0.651537718442292	NOTCH2	1
GO:0010872	regulation of cholesterol esterification	1/896	14/18722	0.49682726232304	0.651537718442292	LAMTOR1	1
GO:0010896	regulation of triglyceride catabolic process	1/896	14/18722	0.49682726232304	0.651537718442292	SORL1	1
GO:0010989	negative regulation of low-density lipoprotein particle clearance	1/896	14/18722	0.49682726232304	0.651537718442292	CSK	1
GO:0018158	protein oxidation	1/896	14/18722	0.49682726232304	0.651537718442292	GPX1	1
GO:0022038	corpus callosum development	1/896	14/18722	0.49682726232304	0.651537718442292	NIN	1
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	1/896	14/18722	0.49682726232304	0.651537718442292	HHEX	1
GO:0032966	negative regulation of collagen biosynthetic process	1/896	14/18722	0.49682726232304	0.651537718442292	RAP1A	1
GO:0034111	negative regulation of homotypic cell-cell adhesion	1/896	14/18722	0.49682726232304	0.651537718442292	SH2B3	1
GO:0035630	bone mineralization involved in bone maturation	1/896	14/18722	0.49682726232304	0.651537718442292	SNX10	1
GO:0035641	locomotory exploration behavior	1/896	14/18722	0.49682726232304	0.651537718442292	LRRK2	1
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	1/896	14/18722	0.49682726232304	0.651537718442292	PTPN2	1
GO:0035810	positive regulation of urine volume	1/896	14/18722	0.49682726232304	0.651537718442292	GNAI2	1
GO:0035815	positive regulation of renal sodium excretion	1/896	14/18722	0.49682726232304	0.651537718442292	GNAI2	1
GO:0036444	calcium import into the mitochondrion	1/896	14/18722	0.49682726232304	0.651537718442292	MICU1	1
GO:0038183	bile acid signaling pathway	1/896	14/18722	0.49682726232304	0.651537718442292	GPBAR1	1
GO:0043173	nucleotide salvage	1/896	14/18722	0.49682726232304	0.651537718442292	UPP1	1
GO:0043455	regulation of secondary metabolic process	1/896	14/18722	0.49682726232304	0.651537718442292	ZEB2	1
GO:0043650	dicarboxylic acid biosynthetic process	1/896	14/18722	0.49682726232304	0.651537718442292	KYNU	1
GO:0043951	negative regulation of cAMP-mediated signaling	1/896	14/18722	0.49682726232304	0.651537718442292	RGS2	1
GO:0044154	histone H3-K14 acetylation	1/896	14/18722	0.49682726232304	0.651537718442292	KMT2A	1
GO:0045006	DNA deamination	1/896	14/18722	0.49682726232304	0.651537718442292	APOBEC3A	1
GO:0045472	response to ether	1/896	14/18722	0.49682726232304	0.651537718442292	PTAFR	1
GO:0045837	negative regulation of membrane potential	1/896	14/18722	0.49682726232304	0.651537718442292	BNIP3L	1
GO:0045989	positive regulation of striated muscle contraction	1/896	14/18722	0.49682726232304	0.651537718442292	RGS2	1
GO:0046479	glycosphingolipid catabolic process	1/896	14/18722	0.49682726232304	0.651537718442292	NAGA	1
GO:0046655	folic acid metabolic process	1/896	14/18722	0.49682726232304	0.651537718442292	MTHFD2	1
GO:0048021	regulation of melanin biosynthetic process	1/896	14/18722	0.49682726232304	0.651537718442292	ZEB2	1
GO:0048291	isotype switching to IgG isotypes	1/896	14/18722	0.49682726232304	0.651537718442292	PTPRC	1
GO:0048681	negative regulation of axon regeneration	1/896	14/18722	0.49682726232304	0.651537718442292	PTEN	1
GO:0050872	white fat cell differentiation	1/896	14/18722	0.49682726232304	0.651537718442292	CTBP2	1
GO:0050930	induction of positive chemotaxis	1/896	14/18722	0.49682726232304	0.651537718442292	CXCL8	1
GO:0051984	positive regulation of chromosome segregation	1/896	14/18722	0.49682726232304	0.651537718442292	HNRNPU	1
GO:0060354	negative regulation of cell adhesion molecule production	1/896	14/18722	0.49682726232304	0.651537718442292	CXCL8	1
GO:0060732	positive regulation of inositol phosphate biosynthetic process	1/896	14/18722	0.49682726232304	0.651537718442292	PTAFR	1
GO:0061709	reticulophagy	1/896	14/18722	0.49682726232304	0.651537718442292	RB1CC1	1
GO:0070141	response to UV-A	1/896	14/18722	0.49682726232304	0.651537718442292	TIMP1	1
GO:0070307	lens fiber cell development	1/896	14/18722	0.49682726232304	0.651537718442292	VIM	1
GO:0070986	left/right axis specification	1/896	14/18722	0.49682726232304	0.651537718442292	NOTCH2	1
GO:0071285	cellular response to lithium ion	1/896	14/18722	0.49682726232304	0.651537718442292	ADCY7	1
GO:0071415	cellular response to purine-containing compound	1/896	14/18722	0.49682726232304	0.651537718442292	SLC8A1	1
GO:0072531	pyrimidine-containing compound transmembrane transport	1/896	14/18722	0.49682726232304	0.651537718442292	AQP9	1
GO:0090239	regulation of histone H4 acetylation	1/896	14/18722	0.49682726232304	0.651537718442292	SPI1	1
GO:0097091	synaptic vesicle clustering	1/896	14/18722	0.49682726232304	0.651537718442292	PTEN	1
GO:0098734	macromolecule depalmitoylation	1/896	14/18722	0.49682726232304	0.651537718442292	PPT1	1
GO:1900037	regulation of cellular response to hypoxia	1/896	14/18722	0.49682726232304	0.651537718442292	TMBIM6	1
GO:1900376	regulation of secondary metabolite biosynthetic process	1/896	14/18722	0.49682726232304	0.651537718442292	ZEB2	1
GO:1901857	positive regulation of cellular respiration	1/896	14/18722	0.49682726232304	0.651537718442292	IFNAR1	1
GO:1902969	mitotic DNA replication	1/896	14/18722	0.49682726232304	0.651537718442292	BCL6	1
GO:1904294	positive regulation of ERAD pathway	1/896	14/18722	0.49682726232304	0.651537718442292	HERPUD1	1
GO:1905065	positive regulation of vascular associated smooth muscle cell differentiation	1/896	14/18722	0.49682726232304	0.651537718442292	SOD2	1
GO:2001256	regulation of store-operated calcium entry	1/896	14/18722	0.49682726232304	0.651537718442292	CD84	1
GO:0016579	protein deubiquitination	7/896	139/18722	0.500149309692466	0.655728903380518	TNFAIP3/USP15/USP3/OTUD1/CYLD/TANK/TAF10	7
GO:0035637	multicellular organismal signaling	8/896	160/18722	0.500992486191663	0.656668830817248	TYMP/FLNA/SLC8A1/KCNE3/CALM2/MEF2A/PRKACA/PLEC	8
GO:0000819	sister chromatid segregation	10/896	202/18722	0.502372931581426	0.658146503061712	DUSP1/RB1/NIPBL/ATM/STAG2/HNRNPU/CHMP1B/NUP62/ZNF207/DYNC1LI1	10
GO:0009913	epidermal cell differentiation	10/896	202/18722	0.502372931581426	0.658146503061712	TXNIP/ZFP36/CSTA/KLF4/ZFP36L1/STK4/ROCK1/FOSL2/ASAH1/PLEC	10
GO:0001569	branching involved in blood vessel morphogenesis	2/896	35/18722	0.504344483896082	0.65890370779792	STK4/TGFBR2	2
GO:0002209	behavioral defense response	2/896	35/18722	0.504344483896082	0.65890370779792	MEF2C/EP300	2
GO:0006084	acetyl-CoA metabolic process	2/896	35/18722	0.504344483896082	0.65890370779792	KYNU/PDK4	2
GO:0006471	protein ADP-ribosylation	2/896	35/18722	0.504344483896082	0.65890370779792	PARP9/PARP14	2
GO:0010664	negative regulation of striated muscle cell apoptotic process	2/896	35/18722	0.504344483896082	0.65890370779792	JAK2/CFLAR	2
GO:0031076	embryonic camera-type eye development	2/896	35/18722	0.504344483896082	0.65890370779792	HIPK1/SP3	2
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	2/896	35/18722	0.504344483896082	0.65890370779792	SDCBP/WAC	2
GO:0050654	chondroitin sulfate proteoglycan metabolic process	2/896	35/18722	0.504344483896082	0.65890370779792	CSGALNACT2/DSE	2
GO:0071108	protein K48-linked deubiquitination	2/896	35/18722	0.504344483896082	0.65890370779792	TNFAIP3/USP15	2
GO:0098801	regulation of renal system process	2/896	35/18722	0.504344483896082	0.65890370779792	CYBA/GNAI2	2
GO:1905898	positive regulation of response to endoplasmic reticulum stress	2/896	35/18722	0.504344483896082	0.65890370779792	PTPN2/HERPUD1	2
GO:0045599	negative regulation of fat cell differentiation	3/896	56/18722	0.505823450167223	0.660338294256959	ZFP36L2/TGFB1/TNF	3
GO:0046622	positive regulation of organ growth	3/896	56/18722	0.505823450167223	0.660338294256959	MEF2C/SERP1/MAPK1	3
GO:0070534	protein K63-linked ubiquitination	3/896	56/18722	0.505823450167223	0.660338294256959	DDX3X/TRIP12/BIRC2	3
GO:0055117	regulation of cardiac muscle contraction	4/896	77/18722	0.506526733096673	0.661090473986398	RGS2/SLC8A1/CALM2/PRKACA	4
GO:0010906	regulation of glucose metabolic process	6/896	119/18722	0.507413930652289	0.662082251209874	FBP1/MIDN/PDK4/IRS2/PTPN2/EP300	6
GO:0003205	cardiac chamber development	8/896	161/18722	0.508097122756966	0.662807407940552	MEF2C/TGFB1/NOTCH2/CNTRL/FKBP1A/HIF1A/TGFBR2/MDM4	8
GO:0006643	membrane lipid metabolic process	10/896	203/18722	0.508701156635683	0.663428965812986	CYP1B1/PSAP/PPT1/HACD4/SPTLC2/NAAA/ELOVL5/ST8SIA4/ASAH1/NAGA	10
GO:0001654	eye development	18/896	371/18722	0.51075641004528	0.665942363661444	VIM/KLF4/CYP1B1/SCO2/NOTCH2/TCIRG1/PFDN5/AGTPBP1/SKIL/STAT3/HIF1A/NIPBL/GNB1/TGFBR2/XRN2/HIPK1/MAX/SP3	18
GO:0042391	regulation of membrane potential	21/896	434/18722	0.511436198361706	0.66633967625091	TSPO/SOD2/LRRK2/FLNA/CD36/CASP1/ARRB2/MEF2C/UCP2/SLC8A1/KCNE3/BID/JUN/PTK2B/GLRX/CHCHD10/CLIC1/BNIP3L/GNAQ/PTEN/PPP3CA	21
GO:0035050	embryonic heart tube development	4/896	78/18722	0.516734018015618	0.66633967625091	MEF2C/NOTCH2/HIF1A/TGFBR2	4
GO:0061045	negative regulation of wound healing	4/896	78/18722	0.516734018015618	0.66633967625091	TNF/ALOX5/SH2B3/PTEN	4
GO:1901616	organic hydroxy compound catabolic process	4/896	78/18722	0.516734018015618	0.66633967625091	ALDH2/SULT1A1/PTEN/NUDT3	4
GO:0050879	multicellular organismal movement	3/896	57/18722	0.517790404905935	0.66633967625091	NR4A1/RCSD1/EEF2	3
GO:0050881	musculoskeletal movement	3/896	57/18722	0.517790404905935	0.66633967625091	NR4A1/RCSD1/EEF2	3
GO:0051155	positive regulation of striated muscle cell differentiation	3/896	57/18722	0.517790404905935	0.66633967625091	ARRB2/MEF2C/TGFB1	3
GO:1902017	regulation of cilium assembly	3/896	57/18722	0.517790404905935	0.66633967625091	CCDC88A/ATG3/CYLD	3
GO:0003203	endocardial cushion morphogenesis	2/896	36/18722	0.519490494393253	0.66633967625091	TGFBR2/MDM4	2
GO:0003230	cardiac atrium development	2/896	36/18722	0.519490494393253	0.66633967625091	NOTCH2/MDM4	2
GO:0008207	C21-steroid hormone metabolic process	2/896	36/18722	0.519490494393253	0.66633967625091	TSPO/EGR1	2
GO:0038179	neurotrophin signaling pathway	2/896	36/18722	0.519490494393253	0.66633967625091	CORO1A/RAP1A	2
GO:0044060	regulation of endocrine process	2/896	36/18722	0.519490494393253	0.66633967625091	RETN/RAB8B	2
GO:0045652	regulation of megakaryocyte differentiation	2/896	36/18722	0.519490494393253	0.66633967625091	MEF2C/CIB1	2
GO:0045738	negative regulation of DNA repair	2/896	36/18722	0.519490494393253	0.66633967625091	SMCHD1/TRIP12	2
GO:0070306	lens fiber cell differentiation	2/896	36/18722	0.519490494393253	0.66633967625091	VIM/SKIL	2
GO:1903539	protein localization to postsynaptic membrane	2/896	36/18722	0.519490494393253	0.66633967625091	RAP1A/ADAM10	2
GO:0002836	positive regulation of response to tumor cell	1/896	15/18722	0.520926191816227	0.66633967625091	HLA-DRB1	1
GO:0002839	positive regulation of immune response to tumor cell	1/896	15/18722	0.520926191816227	0.66633967625091	HLA-DRB1	1
GO:0006089	lactate metabolic process	1/896	15/18722	0.520926191816227	0.66633967625091	HIF1A	1
GO:0006684	sphingomyelin metabolic process	1/896	15/18722	0.520926191816227	0.66633967625091	SPTLC2	1
GO:0006825	copper ion transport	1/896	15/18722	0.520926191816227	0.66633967625091	SLC31A2	1
GO:0010752	regulation of cGMP-mediated signaling	1/896	15/18722	0.520926191816227	0.66633967625091	PTK2B	1
GO:0010889	regulation of sequestering of triglyceride	1/896	15/18722	0.520926191816227	0.66633967625091	OSBPL8	1
GO:0010940	positive regulation of necrotic cell death	1/896	15/18722	0.520926191816227	0.66633967625091	TSPO	1
GO:0014733	regulation of skeletal muscle adaptation	1/896	15/18722	0.520926191816227	0.66633967625091	PPP3CA	1
GO:0016446	somatic hypermutation of immunoglobulin genes	1/896	15/18722	0.520926191816227	0.66633967625091	SAMHD1	1
GO:0018410	C-terminal protein amino acid modification	1/896	15/18722	0.520926191816227	0.66633967625091	AGTPBP1	1
GO:0019511	peptidyl-proline hydroxylation	1/896	15/18722	0.520926191816227	0.66633967625091	CRTAP	1
GO:0030252	growth hormone secretion	1/896	15/18722	0.520926191816227	0.66633967625091	SERP1	1
GO:0032310	prostaglandin secretion	1/896	15/18722	0.520926191816227	0.66633967625091	IL1B	1
GO:0033599	regulation of mammary gland epithelial cell proliferation	1/896	15/18722	0.520926191816227	0.66633967625091	GPX1	1
GO:0034380	high-density lipoprotein particle assembly	1/896	15/18722	0.520926191816227	0.66633967625091	PRKACA	1
GO:0035627	ceramide transport	1/896	15/18722	0.520926191816227	0.66633967625091	PSAP	1
GO:0036124	histone H3-K9 trimethylation	1/896	15/18722	0.520926191816227	0.66633967625091	ARID4A	1
GO:0036376	sodium ion export across plasma membrane	1/896	15/18722	0.520926191816227	0.66633967625091	SLC8A1	1
GO:0042159	lipoprotein catabolic process	1/896	15/18722	0.520926191816227	0.66633967625091	PPT1	1
GO:0042559	pteridine-containing compound biosynthetic process	1/896	15/18722	0.520926191816227	0.66633967625091	GCH1	1
GO:0043252	sodium-independent organic anion transport	1/896	15/18722	0.520926191816227	0.66633967625091	SLCO3A1	1
GO:0043508	negative regulation of JUN kinase activity	1/896	15/18722	0.520926191816227	0.66633967625091	HIPK3	1
GO:0043584	nose development	1/896	15/18722	0.520926191816227	0.66633967625091	SMCHD1	1
GO:0045176	apical protein localization	1/896	15/18722	0.520926191816227	0.66633967625091	ACTB	1
GO:0045217	cell-cell junction maintenance	1/896	15/18722	0.520926191816227	0.66633967625091	CSF1R	1
GO:0045725	positive regulation of glycogen biosynthetic process	1/896	15/18722	0.520926191816227	0.66633967625091	IRS2	1
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	1/896	15/18722	0.520926191816227	0.66633967625091	RB1	1
GO:0046184	aldehyde biosynthetic process	1/896	15/18722	0.520926191816227	0.66633967625091	TKT	1
GO:0046321	positive regulation of fatty acid oxidation	1/896	15/18722	0.520926191816227	0.66633967625091	IRS2	1
GO:0046500	S-adenosylmethionine metabolic process	1/896	15/18722	0.520926191816227	0.66633967625091	MAT2A	1
GO:0046834	lipid phosphorylation	1/896	15/18722	0.520926191816227	0.66633967625091	DGKZ	1
GO:0048308	organelle inheritance	1/896	15/18722	0.520926191816227	0.66633967625091	MAPK1	1
GO:0048313	Golgi inheritance	1/896	15/18722	0.520926191816227	0.66633967625091	MAPK1	1
GO:0048569	post-embryonic animal organ development	1/896	15/18722	0.520926191816227	0.66633967625091	KLF4	1
GO:0051284	positive regulation of sequestering of calcium ion	1/896	15/18722	0.520926191816227	0.66633967625091	CALM2	1
GO:0051299	centrosome separation	1/896	15/18722	0.520926191816227	0.66633967625091	NUP62	1
GO:0051315	attachment of mitotic spindle microtubules to kinetochore	1/896	15/18722	0.520926191816227	0.66633967625091	HNRNPU	1
GO:0060049	regulation of protein glycosylation	1/896	15/18722	0.520926191816227	0.66633967625091	CHP1	1
GO:0060413	atrial septum morphogenesis	1/896	15/18722	0.520926191816227	0.66633967625091	NOTCH2	1
GO:0060766	negative regulation of androgen receptor signaling pathway	1/896	15/18722	0.520926191816227	0.66633967625091	ZBTB7A	1
GO:0070207	protein homotrimerization	1/896	15/18722	0.520926191816227	0.66633967625091	ALOX5AP	1
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	1/896	15/18722	0.520926191816227	0.66633967625091	SORL1	1
GO:0071025	RNA surveillance	1/896	15/18722	0.520926191816227	0.66633967625091	XRN1	1
GO:0071380	cellular response to prostaglandin E stimulus	1/896	15/18722	0.520926191816227	0.66633967625091	GNB1	1
GO:0071871	response to epinephrine	1/896	15/18722	0.520926191816227	0.66633967625091	PRKACA	1
GO:0072075	metanephric mesenchyme development	1/896	15/18722	0.520926191816227	0.66633967625091	STAT1	1
GO:0072224	metanephric glomerulus development	1/896	15/18722	0.520926191816227	0.66633967625091	EGR1	1
GO:0080154	regulation of fertilization	1/896	15/18722	0.520926191816227	0.66633967625091	MYH9	1
GO:0110156	methylguanosine-cap decapping	1/896	15/18722	0.520926191816227	0.66633967625091	ZFP36	1
GO:1900029	positive regulation of ruffle assembly	1/896	15/18722	0.520926191816227	0.66633967625091	PFN1	1
GO:1901660	calcium ion export	1/896	15/18722	0.520926191816227	0.66633967625091	CALM2	1
GO:1901970	positive regulation of mitotic sister chromatid separation	1/896	15/18722	0.520926191816227	0.66633967625091	RB1	1
GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	1/896	15/18722	0.520926191816227	0.66633967625091	G6PD	1
GO:1902902	negative regulation of autophagosome assembly	1/896	15/18722	0.520926191816227	0.66633967625091	LRRK2	1
GO:1903543	positive regulation of exosomal secretion	1/896	15/18722	0.520926191816227	0.66633967625091	SDCBP	1
GO:1903729	regulation of plasma membrane organization	1/896	15/18722	0.520926191816227	0.66633967625091	MYH9	1
GO:1990822	basic amino acid transmembrane transport	1/896	15/18722	0.520926191816227	0.66633967625091	SLC7A7	1
GO:2000104	negative regulation of DNA-dependent DNA replication	1/896	15/18722	0.520926191816227	0.66633967625091	BCL6	1
GO:2001028	positive regulation of endothelial cell chemotaxis	1/896	15/18722	0.520926191816227	0.66633967625091	TMSB4X	1
GO:0003206	cardiac chamber morphogenesis	6/896	121/18722	0.52379642458935	0.669846374302731	MEF2C/TGFB1/NOTCH2/FKBP1A/HIF1A/TGFBR2	6
GO:0001895	retina homeostasis	4/896	79/18722	0.52684170471141	0.673409610765309	LYZ/B2M/ACTB/DRAM2	4
GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	4/896	79/18722	0.52684170471141	0.673409610765309	S100A9/S100A12/CXCL8/RNASE6	4
GO:0050680	negative regulation of epithelial cell proliferation	8/896	164/18722	0.529209218621602	0.676269569054288	B2M/STAT1/MEF2C/TGFB1/TNF/ALOX5/PTEN/RB1	8
GO:0045604	regulation of epidermal cell differentiation	3/896	58/18722	0.529599160250781	0.676435469662159	ZFP36/ZFP36L1/ROCK1	3
GO:2000736	regulation of stem cell differentiation	3/896	58/18722	0.529599160250781	0.676435469662159	ZFP36L2/STAT3/HNRNPU	3
GO:0031109	microtubule polymerization or depolymerization	6/896	122/18722	0.531905617009469	0.679214611850294	HSPA1A/NIN/PAK1/TAOK1/ZNF207/CIB1	6
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2/896	37/18722	0.534323908982578	0.680464899759644	PABPC1/SMG1	2
GO:0003161	cardiac conduction system development	2/896	37/18722	0.534323908982578	0.680464899759644	NOTCH2/CDC42	2
GO:0021532	neural tube patterning	2/896	37/18722	0.534323908982578	0.680464899759644	PRKACA/ATP6AP2	2
GO:0033120	positive regulation of RNA splicing	2/896	37/18722	0.534323908982578	0.680464899759644	HSPA1A/SETX	2
GO:0043687	post-translational protein modification	2/896	37/18722	0.534323908982578	0.680464899759644	AGTPBP1/CRTAP	2
GO:0050775	positive regulation of dendrite morphogenesis	2/896	37/18722	0.534323908982578	0.680464899759644	ACTR2/DBNL	2
GO:0060306	regulation of membrane repolarization	2/896	37/18722	0.534323908982578	0.680464899759644	FLNA/KCNE3	2
GO:0062237	protein localization to postsynapse	2/896	37/18722	0.534323908982578	0.680464899759644	RAP1A/ADAM10	2
GO:0071542	dopaminergic neuron differentiation	2/896	37/18722	0.534323908982578	0.680464899759644	NR4A2/HIF1A	2
GO:0097484	dendrite extension	2/896	37/18722	0.534323908982578	0.680464899759644	CXCR4/ITSN2	2
GO:1904358	positive regulation of telomere maintenance via telomere lengthening	2/896	37/18722	0.534323908982578	0.680464899759644	MAPK1/ATM	2
GO:0009791	post-embryonic development	4/896	80/18722	0.536845672742605	0.683090818120342	KLF4/NR4A2/SERP1/MORC3	4
GO:0021766	hippocampus development	4/896	80/18722	0.536845672742605	0.683090818120342	BTG2/KDM6B/PTEN/XRN2	4
GO:0031570	DNA integrity checkpoint signaling	6/896	123/18722	0.539956753544144	0.683090818120342	TAOK3/CDKN1A/ATM/FOXN3/TAOK1/WAC	6
GO:0006406	mRNA export from nucleus	3/896	59/18722	0.541244475038923	0.683090818120342	NUP214/HHEX/SMG1	3
GO:0006767	water-soluble vitamin metabolic process	3/896	59/18722	0.541244475038923	0.683090818120342	SLC2A3/VNN2/MTHFD2	3
GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus	3/896	59/18722	0.541244475038923	0.683090818120342	NUP214/HHEX/SMG1	3
GO:2000351	regulation of endothelial cell apoptotic process	3/896	59/18722	0.541244475038923	0.683090818120342	TNFAIP3/ITGA4/TNF	3
GO:0033044	regulation of chromosome organization	9/896	187/18722	0.541379944649856	0.683090818120342	DUSP1/RB1/MAPK1/ATM/HNRNPU/XRN1/SMG1/ZNF207/DYNC1LI1	9
GO:0034308	primary alcohol metabolic process	5/896	102/18722	0.542785280885605	0.683090818120342	CYP1B1/ALDH2/SULT1A1/ALDH1A1/NAAA	5
GO:0045833	negative regulation of lipid metabolic process	5/896	102/18722	0.542785280885605	0.683090818120342	IL1B/SORL1/TNF/PIP4K2A/NFKB1	5
GO:1904063	negative regulation of cation transmembrane transport	5/896	102/18722	0.542785280885605	0.683090818120342	RGS2/KCNE3/CALM2/PTEN/CAB39	5
GO:0001574	ganglioside biosynthetic process	1/896	16/18722	0.54387215493873	0.683090818120342	ST8SIA4	1
GO:0001732	formation of cytoplasmic translation initiation complex	1/896	16/18722	0.54387215493873	0.683090818120342	EIF3K	1
GO:0001845	phagolysosome assembly	1/896	16/18722	0.54387215493873	0.683090818120342	CORO1A	1
GO:0001977	renal system process involved in regulation of blood volume	1/896	16/18722	0.54387215493873	0.683090818120342	CYBA	1
GO:0002921	negative regulation of humoral immune response	1/896	16/18722	0.54387215493873	0.683090818120342	PTPN6	1
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	1/896	16/18722	0.54387215493873	0.683090818120342	TGFBR2	1
GO:0006828	manganese ion transport	1/896	16/18722	0.54387215493873	0.683090818120342	SLC11A1	1
GO:0006857	oligopeptide transport	1/896	16/18722	0.54387215493873	0.683090818120342	MGST1	1
GO:0009074	aromatic amino acid family catabolic process	1/896	16/18722	0.54387215493873	0.683090818120342	KYNU	1
GO:0009415	response to water	1/896	16/18722	0.54387215493873	0.683090818120342	PLEC	1
GO:0010225	response to UV-C	1/896	16/18722	0.54387215493873	0.683090818120342	CARD16	1
GO:0014819	regulation of skeletal muscle contraction	1/896	16/18722	0.54387215493873	0.683090818120342	NR4A1	1
GO:0016074	sno(s)RNA metabolic process	1/896	16/18722	0.54387215493873	0.683090818120342	NUDT16	1
GO:0019081	viral translation	1/896	16/18722	0.54387215493873	0.683090818120342	PCBP2	1
GO:0019377	glycolipid catabolic process	1/896	16/18722	0.54387215493873	0.683090818120342	NAGA	1
GO:0021535	cell migration in hindbrain	1/896	16/18722	0.54387215493873	0.683090818120342	FLNA	1
GO:0030033	microvillus assembly	1/896	16/18722	0.54387215493873	0.683090818120342	FXYD5	1
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	1/896	16/18722	0.54387215493873	0.683090818120342	HNRNPU	1
GO:0035067	negative regulation of histone acetylation	1/896	16/18722	0.54387215493873	0.683090818120342	SPI1	1
GO:0035970	peptidyl-threonine dephosphorylation	1/896	16/18722	0.54387215493873	0.683090818120342	DUSP1	1
GO:0042407	cristae formation	1/896	16/18722	0.54387215493873	0.683090818120342	CHCHD10	1
GO:0042574	retinal metabolic process	1/896	16/18722	0.54387215493873	0.683090818120342	CYP1B1	1
GO:0044849	estrous cycle	1/896	16/18722	0.54387215493873	0.683090818120342	EGR1	1
GO:0045721	negative regulation of gluconeogenesis	1/896	16/18722	0.54387215493873	0.683090818120342	EP300	1
GO:0045722	positive regulation of gluconeogenesis	1/896	16/18722	0.54387215493873	0.683090818120342	PTPN2	1
GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	1/896	16/18722	0.54387215493873	0.683090818120342	APOBEC3A	1
GO:0048557	embryonic digestive tract morphogenesis	1/896	16/18722	0.54387215493873	0.683090818120342	NIPBL	1
GO:0050884	neuromuscular process controlling posture	1/896	16/18722	0.54387215493873	0.683090818120342	GCH1	1
GO:0051969	regulation of transmission of nerve impulse	1/896	16/18722	0.54387215493873	0.683090818120342	TYMP	1
GO:0070230	positive regulation of lymphocyte apoptotic process	1/896	16/18722	0.54387215493873	0.683090818120342	LGALS9	1
GO:0070242	thymocyte apoptotic process	1/896	16/18722	0.54387215493873	0.683090818120342	HIF1A	1
GO:0070365	hepatocyte differentiation	1/896	16/18722	0.54387215493873	0.683090818120342	TAF10	1
GO:0070571	negative regulation of neuron projection regeneration	1/896	16/18722	0.54387215493873	0.683090818120342	PTEN	1
GO:0071391	cellular response to estrogen stimulus	1/896	16/18722	0.54387215493873	0.683090818120342	NCOA4	1
GO:0071732	cellular response to nitric oxide	1/896	16/18722	0.54387215493873	0.683090818120342	CFLAR	1
GO:0072283	metanephric renal vesicle morphogenesis	1/896	16/18722	0.54387215493873	0.683090818120342	STAT1	1
GO:0098884	postsynaptic neurotransmitter receptor internalization	1/896	16/18722	0.54387215493873	0.683090818120342	NUMB	1
GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential	1/896	16/18722	0.54387215493873	0.683090818120342	KCNE3	1
GO:0140239	postsynaptic endocytosis	1/896	16/18722	0.54387215493873	0.683090818120342	NUMB	1
GO:1901201	regulation of extracellular matrix assembly	1/896	16/18722	0.54387215493873	0.683090818120342	TGFB1	1
GO:1902101	positive regulation of metaphase/anaphase transition of cell cycle	1/896	16/18722	0.54387215493873	0.683090818120342	RB1	1
GO:1902570	protein localization to nucleolus	1/896	16/18722	0.54387215493873	0.683090818120342	GLUL	1
GO:1904948	midbrain dopaminergic neuron differentiation	1/896	16/18722	0.54387215493873	0.683090818120342	NR4A2	1
GO:1905874	regulation of postsynaptic density organization	1/896	16/18722	0.54387215493873	0.683090818120342	LILRB2	1
GO:1905906	regulation of amyloid fibril formation	1/896	16/18722	0.54387215493873	0.683090818120342	PFDN5	1
GO:2000232	regulation of rRNA processing	1/896	16/18722	0.54387215493873	0.683090818120342	NUDT16	1
GO:0010833	telomere maintenance via telomere lengthening	4/896	81/18722	0.546742076620664	0.686529584863369	MAPK1/ATM/HNRNPU/XRN1	4
GO:0006882	cellular zinc ion homeostasis	2/896	38/18722	0.548839930927499	0.687669593050813	S100A9/S100A8	2
GO:0032373	positive regulation of sterol transport	2/896	38/18722	0.548839930927499	0.687669593050813	NFKBIA/RXRA	2
GO:0032376	positive regulation of cholesterol transport	2/896	38/18722	0.548839930927499	0.687669593050813	NFKBIA/RXRA	2
GO:0032941	secretion by tissue	2/896	38/18722	0.548839930927499	0.687669593050813	CYBA/WNK1	2
GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway	2/896	38/18722	0.548839930927499	0.687669593050813	RHOA/ZBTB7A	2
GO:0035886	vascular associated smooth muscle cell differentiation	2/896	38/18722	0.548839930927499	0.687669593050813	SOD2/EPC1	2
GO:0051930	regulation of sensory perception of pain	2/896	38/18722	0.548839930927499	0.687669593050813	CCL3/PTAFR	2
GO:0099622	cardiac muscle cell membrane repolarization	2/896	38/18722	0.548839930927499	0.687669593050813	FLNA/KCNE3	2
GO:1903725	regulation of phospholipid metabolic process	2/896	38/18722	0.548839930927499	0.687669593050813	CAPN2/CHP1	2
GO:0002027	regulation of heart rate	5/896	103/18722	0.551537132228612	0.690716259263427	SLC8A1/KCNE3/GCH1/CALM2/PRKACA	5
GO:0030148	sphingolipid biosynthetic process	5/896	103/18722	0.551537132228612	0.690716259263427	HACD4/SPTLC2/ELOVL5/ST8SIA4/ASAH1	5
GO:0006893	Golgi to plasma membrane transport	3/896	60/18722	0.552721633036434	0.691866477358001	VAMP5/CSK/RAB10	3
GO:0019731	antibacterial humoral response	3/896	60/18722	0.552721633036434	0.691866477358001	HLA-A/HLA-E/RNASE6	3
GO:0016331	morphogenesis of embryonic epithelium	7/896	147/18722	0.559878508979792	0.698886233566696	VASP/TGFB1/STK4/PRKACA/PFN1/HIF1A/PLXNB2	7
GO:0016233	telomere capping	2/896	39/18722	0.563034936851351	0.698886233566696	MAPK1/ATM	2
GO:0017158	regulation of calcium ion-dependent exocytosis	2/896	39/18722	0.563034936851351	0.698886233566696	GNAI2/RAP1B	2
GO:0021587	cerebellum morphogenesis	2/896	39/18722	0.563034936851351	0.698886233566696	AGTPBP1/MTPN	2
GO:0031507	heterochromatin assembly	2/896	39/18722	0.563034936851351	0.698886233566696	SMCHD1/MBD2	2
GO:0045823	positive regulation of heart contraction	2/896	39/18722	0.563034936851351	0.698886233566696	RGS2/GCH1	2
GO:0051084	'de novo' posttranslational protein folding	2/896	39/18722	0.563034936851351	0.698886233566696	CD74/HSPA1A	2
GO:0051931	regulation of sensory perception	2/896	39/18722	0.563034936851351	0.698886233566696	CCL3/PTAFR	2
GO:0090207	regulation of triglyceride metabolic process	2/896	39/18722	0.563034936851351	0.698886233566696	SORL1/MBOAT7	2
GO:0006937	regulation of muscle contraction	8/896	169/18722	0.563618975624109	0.698886233566696	RGS2/PTGS2/NR4A1/SLC8A1/RHOA/PTAFR/CALM2/PRKACA	8
GO:0030199	collagen fibril organization	3/896	61/18722	0.564026420958292	0.698886233566696	CYP1B1/RB1/CRTAP	3
GO:0030258	lipid modification	10/896	212/18722	0.564453285591734	0.698886233566696	ALOX5/INPP5D/PDK4/PRKAG2/PTEN/DGKZ/DECR1/MBOAT7/LAMTOR1/IRS2	10
GO:0001710	mesodermal cell fate commitment	1/896	17/18722	0.565720254434876	0.698886233566696	KLF4	1
GO:0002031	G protein-coupled receptor internalization	1/896	17/18722	0.565720254434876	0.698886233566696	ARRB2	1
GO:0003184	pulmonary valve morphogenesis	1/896	17/18722	0.565720254434876	0.698886233566696	NOTCH2	1
GO:0006390	mitochondrial transcription	1/896	17/18722	0.565720254434876	0.698886233566696	CHCHD10	1
GO:0006677	glycosylceramide metabolic process	1/896	17/18722	0.565720254434876	0.698886233566696	NAGA	1
GO:0006895	Golgi to endosome transport	1/896	17/18722	0.565720254434876	0.698886233566696	VPS13C	1
GO:0007379	segment specification	1/896	17/18722	0.565720254434876	0.698886233566696	MAFB	1
GO:0007625	grooming behavior	1/896	17/18722	0.565720254434876	0.698886233566696	PPT1	1
GO:0009084	glutamine family amino acid biosynthetic process	1/896	17/18722	0.565720254434876	0.698886233566696	GLUL	1
GO:0009812	flavonoid metabolic process	1/896	17/18722	0.565720254434876	0.698886233566696	SULT1A1	1
GO:0010566	regulation of ketone biosynthetic process	1/896	17/18722	0.565720254434876	0.698886233566696	EGR1	1
GO:0010612	regulation of cardiac muscle adaptation	1/896	17/18722	0.565720254434876	0.698886233566696	PPP3CA	1
GO:0015867	ATP transport	1/896	17/18722	0.565720254434876	0.698886233566696	SLC25A24	1
GO:0016264	gap junction assembly	1/896	17/18722	0.565720254434876	0.698886233566696	IL1B	1
GO:0021692	cerebellar Purkinje cell layer morphogenesis	1/896	17/18722	0.565720254434876	0.698886233566696	AGTPBP1	1
GO:0030322	stabilization of membrane potential	1/896	17/18722	0.565720254434876	0.698886233566696	CHCHD10	1
GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway	1/896	17/18722	0.565720254434876	0.698886233566696	TMEM50A	1
GO:0035729	cellular response to hepatocyte growth factor stimulus	1/896	17/18722	0.565720254434876	0.698886233566696	CREB1	1
GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	1/896	17/18722	0.565720254434876	0.698886233566696	ATM	1
GO:0036166	phenotypic switching	1/896	17/18722	0.565720254434876	0.698886233566696	SOD2	1
GO:0042339	keratan sulfate metabolic process	1/896	17/18722	0.565720254434876	0.698886233566696	GNS	1
GO:0042448	progesterone metabolic process	1/896	17/18722	0.565720254434876	0.698886233566696	EGR1	1
GO:0043117	positive regulation of vascular permeability	1/896	17/18722	0.565720254434876	0.698886233566696	TGFB1	1
GO:0043649	dicarboxylic acid catabolic process	1/896	17/18722	0.565720254434876	0.698886233566696	GLUL	1
GO:0046855	inositol phosphate dephosphorylation	1/896	17/18722	0.565720254434876	0.698886233566696	PTEN	1
GO:0048521	negative regulation of behavior	1/896	17/18722	0.565720254434876	0.698886233566696	RETN	1
GO:0051797	regulation of hair follicle development	1/896	17/18722	0.565720254434876	0.698886233566696	TNF	1
GO:0055003	cardiac myofibril assembly	1/896	17/18722	0.565720254434876	0.698886233566696	MEF2A	1
GO:0060033	anatomical structure regression	1/896	17/18722	0.565720254434876	0.698886233566696	SPI1	1
GO:0061577	calcium ion transmembrane transport via high voltage-gated calcium channel	1/896	17/18722	0.565720254434876	0.698886233566696	G6PD	1
GO:0061952	midbody abscission	1/896	17/18722	0.565720254434876	0.698886233566696	CHMP1B	1
GO:0070293	renal absorption	1/896	17/18722	0.565720254434876	0.698886233566696	SGK1	1
GO:0070593	dendrite self-avoidance	1/896	17/18722	0.565720254434876	0.698886233566696	EMB	1
GO:0070875	positive regulation of glycogen metabolic process	1/896	17/18722	0.565720254434876	0.698886233566696	IRS2	1
GO:0090036	regulation of protein kinase C signaling	1/896	17/18722	0.565720254434876	0.698886233566696	MYADM	1
GO:0090136	epithelial cell-cell adhesion	1/896	17/18722	0.565720254434876	0.698886233566696	CYP1B1	1
GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II	1/896	17/18722	0.565720254434876	0.698886233566696	TGFB1	1
GO:1903242	regulation of cardiac muscle hypertrophy in response to stress	1/896	17/18722	0.565720254434876	0.698886233566696	PPP3CA	1
GO:1903358	regulation of Golgi organization	1/896	17/18722	0.565720254434876	0.698886233566696	MAPK1	1
GO:1903541	regulation of exosomal secretion	1/896	17/18722	0.565720254434876	0.698886233566696	SDCBP	1
GO:1904262	negative regulation of TORC1 signaling	1/896	17/18722	0.565720254434876	0.698886233566696	ATM	1
GO:1904355	positive regulation of telomere capping	1/896	17/18722	0.565720254434876	0.698886233566696	MAPK1	1
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	1/896	17/18722	0.565720254434876	0.698886233566696	STAT1	1
GO:0046785	microtubule polymerization	4/896	83/18722	0.566198148271974	0.699310512743419	HSPA1A/NIN/PAK1/ZNF207	4
GO:0002181	cytoplasmic translation	7/896	148/18722	0.56712318967946	0.700120510211932	RPS9/RPL28/CNBP/EIF2S3/ZNF385A/EIF3K/EEF2	7
GO:0035148	tube formation	7/896	148/18722	0.56712318967946	0.700120510211932	VASP/TGFB1/STK4/PRKACA/PFN1/HIF1A/PLXNB2	7
GO:0000041	transition metal ion transport	5/896	105/18722	0.568791869952632	0.70201388600466	B2M/SLC11A1/FTL/FTH1/SLC31A2	5
GO:0007062	sister chromatid cohesion	3/896	62/18722	0.575155106615163	0.708665578580835	RB1/NIPBL/STAG2	3
GO:0007588	excretion	3/896	62/18722	0.575155106615163	0.708665578580835	GNAI2/AQP9/HMOX1	3
GO:0019933	cAMP-mediated signaling	3/896	62/18722	0.575155106615163	0.708665578580835	RGS2/CAP1/AHR	3
GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	3/896	62/18722	0.575155106615163	0.708665578580835	NUMB/RAP1A/ADAM10	3
GO:0002088	lens development in camera-type eye	4/896	84/18722	0.575751444167421	0.708665578580835	VIM/SKIL/TGFBR2/HIPK1	4
GO:0006112	energy reserve metabolic process	4/896	84/18722	0.575751444167421	0.708665578580835	PRKAG2/PYGL/IRS2/RB1CC1	4
GO:0006405	RNA export from nucleus	4/896	84/18722	0.575751444167421	0.708665578580835	NUP214/HHEX/NUP62/SMG1	4
GO:0032508	DNA duplex unwinding	4/896	84/18722	0.575751444167421	0.708665578580835	SETX/CHD1/CHD9/DDX3X	4
GO:0042310	vasoconstriction	4/896	84/18722	0.575751444167421	0.708665578580835	PTGS2/SLC8A1/RHOA/TBXAS1	4
GO:0044242	cellular lipid catabolic process	10/896	214/18722	0.576494912347165	0.708665578580835	CYP1B1/AOAH/GPCPD1/PPT1/SORL1/PLBD1/ASAH1/DECR1/IRS2/NAGA	10
GO:0006730	one-carbon metabolic process	2/896	40/18722	0.576906375641465	0.708665578580835	MTHFD2/MAT2A	2
GO:0014037	Schwann cell differentiation	2/896	40/18722	0.576906375641465	0.708665578580835	DICER1/PLEC	2
GO:0031111	negative regulation of microtubule polymerization or depolymerization	2/896	40/18722	0.576906375641465	0.708665578580835	TAOK1/CIB1	2
GO:0032094	response to food	2/896	40/18722	0.576906375641465	0.708665578580835	G6PD/PLEC	2
GO:0032892	positive regulation of organic acid transport	2/896	40/18722	0.576906375641465	0.708665578580835	IL1B/ACSL1	2
GO:0045740	positive regulation of DNA replication	2/896	40/18722	0.576906375641465	0.708665578580835	JUN/CDC42	2
GO:0055069	zinc ion homeostasis	2/896	40/18722	0.576906375641465	0.708665578580835	S100A9/S100A8	2
GO:0055081	anion homeostasis	2/896	40/18722	0.576906375641465	0.708665578580835	KCNE3/TBXAS1	2
GO:0072210	metanephric nephron development	2/896	40/18722	0.576906375641465	0.708665578580835	EGR1/STAT1	2
GO:1901998	toxin transport	2/896	40/18722	0.576906375641465	0.708665578580835	CASP1/ADAM10	2
GO:0002062	chondrocyte differentiation	5/896	106/18722	0.577289736039092	0.708801680155646	MEF2C/TGFBI/TGFB1/SULF2/TGFBR2	5
GO:0006766	vitamin metabolic process	5/896	106/18722	0.577289736039092	0.708801680155646	SLC2A3/TNF/VNN2/MTHFD2/NFKB1	5
GO:0043010	camera-type eye development	15/896	322/18722	0.580386025124629	0.712402131553978	VIM/KLF4/CYP1B1/NOTCH2/TCIRG1/PFDN5/AGTPBP1/SKIL/HIF1A/GNB1/TGFBR2/XRN2/HIPK1/MAX/SP3	15
GO:0030198	extracellular matrix organization	14/896	301/18722	0.582520929784304	0.712402131553978	CTSS/LCP1/CST3/TNFRSF1B/CYP1B1/TGFBI/TGFB1/SULF2/TNF/TNFRSF1A/CFLAR/RB1/CRTAP/ADAM10	14
GO:0001656	metanephros development	4/896	85/18722	0.585184418796906	0.712402131553978	EGR1/STAT1/CTSH/NIPBL	4
GO:0021761	limbic system development	5/896	107/18722	0.585698176436424	0.712402131553978	BTG2/KDM6B/PTEN/ARPC5/XRN2	5
GO:0001756	somitogenesis	3/896	63/18722	0.586104417261885	0.712402131553978	LFNG/ABI1/EP300	3
GO:2000756	regulation of peptidyl-lysine acetylation	3/896	63/18722	0.586104417261885	0.712402131553978	IL1B/SPI1/KMT2A	3
GO:0002076	osteoblast development	1/896	18/18722	0.586522962375338	0.712402131553978	JUND	1
GO:0003128	heart field specification	1/896	18/18722	0.586522962375338	0.712402131553978	MEF2C	1
GO:0003417	growth plate cartilage development	1/896	18/18722	0.586522962375338	0.712402131553978	TGFBR2	1
GO:0006085	acetyl-CoA biosynthetic process	1/896	18/18722	0.586522962375338	0.712402131553978	PDK4	1
GO:0006337	nucleosome disassembly	1/896	18/18722	0.586522962375338	0.712402131553978	ARID1A	1
GO:0006625	protein targeting to peroxisome	1/896	18/18722	0.586522962375338	0.712402131553978	RAB8B	1
GO:0006991	response to sterol depletion	1/896	18/18722	0.586522962375338	0.712402131553978	LYN	1
GO:0009404	toxin metabolic process	1/896	18/18722	0.586522962375338	0.712402131553978	CYP1B1	1
GO:0010985	negative regulation of lipoprotein particle clearance	1/896	18/18722	0.586522962375338	0.712402131553978	CSK	1
GO:0021534	cell proliferation in hindbrain	1/896	18/18722	0.586522962375338	0.712402131553978	C5AR1	1
GO:0030299	intestinal cholesterol absorption	1/896	18/18722	0.586522962375338	0.712402131553978	CD36	1
GO:0031000	response to caffeine	1/896	18/18722	0.586522962375338	0.712402131553978	SLC8A1	1
GO:0032305	positive regulation of icosanoid secretion	1/896	18/18722	0.586522962375338	0.712402131553978	IL1B	1
GO:0032769	negative regulation of monooxygenase activity	1/896	18/18722	0.586522962375338	0.712402131553978	NFKB1	1
GO:0032785	negative regulation of DNA-templated transcription, elongation	1/896	18/18722	0.586522962375338	0.712402131553978	HNRNPU	1
GO:0034433	steroid esterification	1/896	18/18722	0.586522962375338	0.712402131553978	LAMTOR1	1
GO:0034434	sterol esterification	1/896	18/18722	0.586522962375338	0.712402131553978	LAMTOR1	1
GO:0034435	cholesterol esterification	1/896	18/18722	0.586522962375338	0.712402131553978	LAMTOR1	1
GO:0042693	muscle cell fate commitment	1/896	18/18722	0.586522962375338	0.712402131553978	MEF2C	1
GO:0045116	protein neddylation	1/896	18/18722	0.586522962375338	0.712402131553978	HIF1A	1
GO:0045623	negative regulation of T-helper cell differentiation	1/896	18/18722	0.586522962375338	0.712402131553978	BCL6	1
GO:0045653	negative regulation of megakaryocyte differentiation	1/896	18/18722	0.586522962375338	0.712402131553978	CIB1	1
GO:0046838	phosphorylated carbohydrate dephosphorylation	1/896	18/18722	0.586522962375338	0.712402131553978	PTEN	1
GO:0048268	clathrin coat assembly	1/896	18/18722	0.586522962375338	0.712402131553978	PICALM	1
GO:0048535	lymph node development	1/896	18/18722	0.586522962375338	0.712402131553978	TGFB1	1
GO:0048643	positive regulation of skeletal muscle tissue development	1/896	18/18722	0.586522962375338	0.712402131553978	MEF2C	1
GO:0051782	negative regulation of cell division	1/896	18/18722	0.586522962375338	0.712402131553978	TXNIP	1
GO:0060192	negative regulation of lipase activity	1/896	18/18722	0.586522962375338	0.712402131553978	RGS2	1
GO:0060457	negative regulation of digestive system process	1/896	18/18722	0.586522962375338	0.712402131553978	WNK1	1
GO:0060749	mammary gland alveolus development	1/896	18/18722	0.586522962375338	0.712402131553978	HIF1A	1
GO:0061377	mammary gland lobule development	1/896	18/18722	0.586522962375338	0.712402131553978	HIF1A	1
GO:0071318	cellular response to ATP	1/896	18/18722	0.586522962375338	0.712402131553978	PTGS2	1
GO:0072234	metanephric nephron tubule development	1/896	18/18722	0.586522962375338	0.712402131553978	STAT1	1
GO:0072662	protein localization to peroxisome	1/896	18/18722	0.586522962375338	0.712402131553978	RAB8B	1
GO:0072663	establishment of protein localization to peroxisome	1/896	18/18722	0.586522962375338	0.712402131553978	RAB8B	1
GO:0090493	catecholamine uptake	1/896	18/18722	0.586522962375338	0.712402131553978	ACTB	1
GO:0097094	craniofacial suture morphogenesis	1/896	18/18722	0.586522962375338	0.712402131553978	FOXN3	1
GO:0097107	postsynaptic density assembly	1/896	18/18722	0.586522962375338	0.712402131553978	PTEN	1
GO:1900006	positive regulation of dendrite development	1/896	18/18722	0.586522962375338	0.712402131553978	IQGAP1	1
GO:2001135	regulation of endocytic recycling	1/896	18/18722	0.586522962375338	0.712402131553978	SORL1	1
GO:0043062	extracellular structure organization	14/896	302/18722	0.587553414552523	0.713487113959297	CTSS/LCP1/CST3/TNFRSF1B/CYP1B1/TGFBI/TGFB1/SULF2/TNF/TNFRSF1A/CFLAR/RB1/CRTAP/ADAM10	14
GO:0030902	hindbrain development	7/896	151/18722	0.58851909991727	0.714326216725723	AIF1/C5AR1/FLNA/MAFB/AGTPBP1/PAK1/MTPN	7
GO:0048592	eye morphogenesis	7/896	151/18722	0.58851909991727	0.714326216725723	NOTCH2/AGTPBP1/STAT3/HIF1A/NIPBL/HIPK1/SP3	7
GO:0098813	nuclear chromosome segregation	13/896	281/18722	0.590120578081541	0.715671022876321	DUSP1/ACTR2/ACTR3/CDC42/RB1/NIPBL/ATM/STAG2/HNRNPU/CHMP1B/NUP62/ZNF207/DYNC1LI1	13
GO:0010907	positive regulation of glucose metabolic process	2/896	41/18722	0.590452674324609	0.715671022876321	IRS2/PTPN2	2
GO:0031062	positive regulation of histone methylation	2/896	41/18722	0.590452674324609	0.715671022876321	KMT2E/KMT2A	2
GO:0055023	positive regulation of cardiac muscle tissue growth	2/896	41/18722	0.590452674324609	0.715671022876321	MEF2C/MAPK1	2
GO:1901385	regulation of voltage-gated calcium channel activity	2/896	41/18722	0.590452674324609	0.715671022876321	KCNE3/AHNAK	2
GO:1903524	positive regulation of blood circulation	2/896	41/18722	0.590452674324609	0.715671022876321	RGS2/GCH1	2
GO:0007059	chromosome segregation	16/896	346/18722	0.592612315575446	0.718121307853657	DUSP1/ACTR2/PLSCR1/ACTR3/CDC42/RB1/NIPBL/ATM/STAG2/HNRNPU/DDX3X/NR3C1/CHMP1B/NUP62/ZNF207/DYNC1LI1	16
GO:0034440	lipid oxidation	5/896	108/18722	0.594015061578871	0.719573206918708	ALOX5/PDK4/PRKAG2/DECR1/IRS2	5
GO:0032413	negative regulation of ion transmembrane transporter activity	4/896	86/18722	0.594494505771817	0.719573206918708	KCNE3/CALM2/PTEN/CAB39	4
GO:0048864	stem cell development	4/896	86/18722	0.594494505771817	0.719573206918708	PTPRC/HIF1A/MAPK1/CORO1C	4
GO:0006282	regulation of DNA repair	6/896	130/18722	0.594502224597133	0.719573206918708	ACTR2/WAS/PARP9/SMCHD1/DTX3L/TRIP12	6
GO:0030534	adult behavior	6/896	130/18722	0.594502224597133	0.719573206918708	ARRB2/NR4A2/PPT1/AGTPBP1/CSTB/PTEN	6
GO:0016126	sterol biosynthetic process	3/896	64/18722	0.596871518213325	0.721601293869713	G6PD/PRKAG2/LBR	3
GO:0017156	calcium-ion regulated exocytosis	3/896	64/18722	0.596871518213325	0.721601293869713	GNAI2/RAP1B/MYH9	3
GO:0030104	water homeostasis	3/896	64/18722	0.596871518213325	0.721601293869713	AQP9/PRKACA/PLEC	3
GO:0045995	regulation of embryonic development	3/896	64/18722	0.596871518213325	0.721601293869713	CFL1/NIPBL/TRIP12	3
GO:1903018	regulation of glycoprotein metabolic process	3/896	64/18722	0.596871518213325	0.721601293869713	CST3/HBEGF/CHP1	3
GO:0006936	muscle contraction	16/896	347/18722	0.597282487853377	0.721930332169513	RGS2/FLNA/PTGS2/NR4A1/TPM3/RCSD1/SLC8A1/KCNE3/SULF2/CXCR4/RHOA/PTAFR/CALM2/PRKACA/ROCK1/EEF2	16
GO:0045229	external encapsulating structure organization	14/896	304/18722	0.597541458054904	0.722075539810306	CTSS/LCP1/CST3/TNFRSF1B/CYP1B1/TGFBI/TGFB1/SULF2/TNF/TNFRSF1A/CFLAR/RB1/CRTAP/ADAM10	14
GO:0001763	morphogenesis of a branching structure	9/896	196/18722	0.598447450358547	0.723002366855936	LRRK2/SOCS3/CTSH/CTSZ/TNF/STK4/PAK1/GRB2/TGFBR2	9
GO:0008380	RNA splicing	20/896	434/18722	0.60200673720473	0.725281418455106	PABPC1/MBNL1/CELF2/HSPA1A/SETX/AHNAK/SCAF11/DDX5/PTBP3/IVNS1ABP/SF3B1/ZBTB7A/YBX1/HNRNPU/CLK1/QKI/CDC40/TMBIM6/CELF1/LSM10	20
GO:0000723	telomere maintenance	6/896	131/18722	0.602011910188603	0.725281418455106	SP100/MAPK1/ATM/HNRNPU/XRN1/SMG1	6
GO:0034766	negative regulation of ion transmembrane transport	5/896	109/18722	0.602238409173422	0.725281418455106	RGS2/KCNE3/CALM2/PTEN/CAB39	5
GO:0072009	nephron epithelium development	5/896	109/18722	0.602238409173422	0.725281418455106	STAT1/MEF2C/PECAM1/IQGAP1/NOTCH2	5
GO:0000266	mitochondrial fission	2/896	42/18722	0.603673150479206	0.725281418455106	LRRK2/STAT2	2
GO:0009154	purine ribonucleotide catabolic process	2/896	42/18722	0.603673150479206	0.725281418455106	NUDT16/NUDT3	2
GO:0021575	hindbrain morphogenesis	2/896	42/18722	0.603673150479206	0.725281418455106	AGTPBP1/MTPN	2
GO:0021879	forebrain neuron differentiation	2/896	42/18722	0.603673150479206	0.725281418455106	B2M/ZSWIM6	2
GO:0045047	protein targeting to ER	2/896	42/18722	0.603673150479206	0.725281418455106	SPCS3/HERPUD1	2
GO:0060999	positive regulation of dendritic spine development	2/896	42/18722	0.603673150479206	0.725281418455106	ACTR2/DBNL	2
GO:0071312	cellular response to alkaloid	2/896	42/18722	0.603673150479206	0.725281418455106	AIF1/SLC8A1	2
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	2/896	42/18722	0.603673150479206	0.725281418455106	KLF4/RHOA	2
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	2/896	42/18722	0.603673150479206	0.725281418455106	XRN2/XRN1	2
GO:0007029	endoplasmic reticulum organization	4/896	87/18722	0.603679373874185	0.725281418455106	LRRK2/SHTN1/RTN3/RAB10	4
GO:0006044	N-acetylglucosamine metabolic process	1/896	19/18722	0.606330245614843	0.725281418455106	NAGK	1
GO:0006144	purine nucleobase metabolic process	1/896	19/18722	0.606330245614843	0.725281418455106	DPYD	1
GO:0006309	apoptotic DNA fragmentation	1/896	19/18722	0.606330245614843	0.725281418455106	DICER1	1
GO:0006491	N-glycan processing	1/896	19/18722	0.606330245614843	0.725281418455106	ST8SIA4	1
GO:0007603	phototransduction, visible light	1/896	19/18722	0.606330245614843	0.725281418455106	GNAQ	1
GO:0010544	negative regulation of platelet activation	1/896	19/18722	0.606330245614843	0.725281418455106	SH2B3	1
GO:0010885	regulation of cholesterol storage	1/896	19/18722	0.606330245614843	0.725281418455106	CD36	1
GO:0019373	epoxygenase P450 pathway	1/896	19/18722	0.606330245614843	0.725281418455106	CYP1B1	1
GO:0035728	response to hepatocyte growth factor	1/896	19/18722	0.606330245614843	0.725281418455106	CREB1	1
GO:0045603	positive regulation of endothelial cell differentiation	1/896	19/18722	0.606330245614843	0.725281418455106	BTG1	1
GO:0045780	positive regulation of bone resorption	1/896	19/18722	0.606330245614843	0.725281418455106	SYK	1
GO:0045821	positive regulation of glycolytic process	1/896	19/18722	0.606330245614843	0.725281418455106	HIF1A	1
GO:0045947	negative regulation of translational initiation	1/896	19/18722	0.606330245614843	0.725281418455106	EIF4EBP1	1
GO:0046716	muscle cell cellular homeostasis	1/896	19/18722	0.606330245614843	0.725281418455106	HIF1A	1
GO:0051444	negative regulation of ubiquitin-protein transferase activity	1/896	19/18722	0.606330245614843	0.725281418455106	DTX3L	1
GO:0060065	uterus development	1/896	19/18722	0.606330245614843	0.725281418455106	NIPBL	1
GO:0070989	oxidative demethylation	1/896	19/18722	0.606330245614843	0.725281418455106	TET2	1
GO:0072074	kidney mesenchyme development	1/896	19/18722	0.606330245614843	0.725281418455106	STAT1	1
GO:0072077	renal vesicle morphogenesis	1/896	19/18722	0.606330245614843	0.725281418455106	STAT1	1
GO:0086014	atrial cardiac muscle cell action potential	1/896	19/18722	0.606330245614843	0.725281418455106	FLNA	1
GO:0086026	atrial cardiac muscle cell to AV node cell signaling	1/896	19/18722	0.606330245614843	0.725281418455106	FLNA	1
GO:0086066	atrial cardiac muscle cell to AV node cell communication	1/896	19/18722	0.606330245614843	0.725281418455106	FLNA	1
GO:0097623	potassium ion export across plasma membrane	1/896	19/18722	0.606330245614843	0.725281418455106	KCNE3	1
GO:1901881	positive regulation of protein depolymerization	1/896	19/18722	0.606330245614843	0.725281418455106	PLEK	1
GO:1903204	negative regulation of oxidative stress-induced neuron death	1/896	19/18722	0.606330245614843	0.725281418455106	HIF1A	1
GO:2000042	negative regulation of double-strand break repair via homologous recombination	1/896	19/18722	0.606330245614843	0.725281418455106	SMCHD1	1
GO:2000319	regulation of T-helper 17 cell differentiation	1/896	19/18722	0.606330245614843	0.725281418455106	NFKBIZ	1
GO:2000369	regulation of clathrin-dependent endocytosis	1/896	19/18722	0.606330245614843	0.725281418455106	BMP2K	1
GO:2000831	regulation of steroid hormone secretion	1/896	19/18722	0.606330245614843	0.725281418455106	RETN	1
GO:0045682	regulation of epidermis development	3/896	65/18722	0.60745399178494	0.725957769134529	ZFP36/ZFP36L1/ROCK1	3
GO:0046513	ceramide biosynthetic process	3/896	65/18722	0.60745399178494	0.725957769134529	SPTLC2/ST8SIA4/ASAH1	3
GO:0048645	animal organ formation	3/896	65/18722	0.60745399178494	0.725957769134529	MEF2C/MAPK1/TGFBR2	3
GO:0051310	metaphase plate congression	3/896	65/18722	0.60745399178494	0.725957769134529	HNRNPU/CHMP1B/NUP62	3
GO:0022618	ribonucleoprotein complex assembly	10/896	220/18722	0.611714278357163	0.730881222544361	CELF2/SETX/SCAF11/EIF2S3/ADAR/ATM/SF3B1/EIF3K/DICER1/CELF1	10
GO:0014014	negative regulation of gliogenesis	2/896	43/18722	0.616567930775333	0.735497662376722	TSPO/DICER1	2
GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	2/896	43/18722	0.616567930775333	0.735497662376722	FXYD5/SELL	2
GO:0032365	intracellular lipid transport	2/896	43/18722	0.616567930775333	0.735497662376722	NPC2/PIP4K2A	2
GO:0046717	acid secretion	2/896	43/18722	0.616567930775333	0.735497662376722	SNX10/SGK1	2
GO:0061383	trabecula morphogenesis	2/896	43/18722	0.616567930775333	0.735497662376722	RHOA/FKBP1A	2
GO:0140353	lipid export from cell	2/896	43/18722	0.616567930775333	0.735497662376722	IL1B/RETN	2
GO:1901381	positive regulation of potassium ion transmembrane transport	2/896	43/18722	0.616567930775333	0.735497662376722	FLNA/WNK1	2
GO:0019229	regulation of vasoconstriction	3/896	66/18722	0.617849816607658	0.73652003121165	PTGS2/RHOA/TBXAS1	3
GO:0050909	sensory perception of taste	3/896	66/18722	0.617849816607658	0.73652003121165	CD36/PLCB2/GNB1	3
GO:0050918	positive chemotaxis	3/896	66/18722	0.617849816607658	0.73652003121165	CORO1A/CCL3/CXCL8	3
GO:0006805	xenobiotic metabolic process	5/896	111/18722	0.618397280951955	0.73700372553417	S100A12/CYP1B1/SULT1A1/ACSL1/AHR	5
GO:0002115	store-operated calcium entry	1/896	20/18722	0.625189685273139	0.739843356793082	CD84	1
GO:0006346	DNA methylation-dependent heterochromatin assembly	1/896	20/18722	0.625189685273139	0.739843356793082	MBD2	1
GO:0006525	arginine metabolic process	1/896	20/18722	0.625189685273139	0.739843356793082	SLC7A7	1
GO:0006590	thyroid hormone generation	1/896	20/18722	0.625189685273139	0.739843356793082	CTSB	1
GO:0006851	mitochondrial calcium ion transmembrane transport	1/896	20/18722	0.625189685273139	0.739843356793082	MICU1	1
GO:0006883	cellular sodium ion homeostasis	1/896	20/18722	0.625189685273139	0.739843356793082	SLC8A1	1
GO:0006896	Golgi to vacuole transport	1/896	20/18722	0.625189685273139	0.739843356793082	LAPTM5	1
GO:0010801	negative regulation of peptidyl-threonine phosphorylation	1/896	20/18722	0.625189685273139	0.739843356793082	CALM2	1
GO:0010893	positive regulation of steroid biosynthetic process	1/896	20/18722	0.625189685273139	0.739843356793082	TNF	1
GO:0015919	peroxisomal membrane transport	1/896	20/18722	0.625189685273139	0.739843356793082	RAB8B	1
GO:0017121	plasma membrane phospholipid scrambling	1/896	20/18722	0.625189685273139	0.739843356793082	PLSCR1	1
GO:0030150	protein import into mitochondrial matrix	1/896	20/18722	0.625189685273139	0.739843356793082	TOMM7	1
GO:0031498	chromatin disassembly	1/896	20/18722	0.625189685273139	0.739843356793082	ARID1A	1
GO:0031645	negative regulation of nervous system process	1/896	20/18722	0.625189685273139	0.739843356793082	PTEN	1
GO:0032986	protein-DNA complex disassembly	1/896	20/18722	0.625189685273139	0.739843356793082	ARID1A	1
GO:0043046	DNA methylation involved in gamete generation	1/896	20/18722	0.625189685273139	0.739843356793082	KDM1B	1
GO:0046931	pore complex assembly	1/896	20/18722	0.625189685273139	0.739843356793082	ADAM10	1
GO:0060231	mesenchymal to epithelial transition	1/896	20/18722	0.625189685273139	0.739843356793082	STAT1	1
GO:0070166	enamel mineralization	1/896	20/18722	0.625189685273139	0.739843356793082	TCIRG1	1
GO:0071379	cellular response to prostaglandin stimulus	1/896	20/18722	0.625189685273139	0.739843356793082	GNB1	1
GO:0071731	response to nitric oxide	1/896	20/18722	0.625189685273139	0.739843356793082	CFLAR	1
GO:0072087	renal vesicle development	1/896	20/18722	0.625189685273139	0.739843356793082	STAT1	1
GO:0097150	neuronal stem cell population maintenance	1/896	20/18722	0.625189685273139	0.739843356793082	HOOK3	1
GO:0097320	plasma membrane tubulation	1/896	20/18722	0.625189685273139	0.739843356793082	BIN2	1
GO:0097503	sialylation	1/896	20/18722	0.625189685273139	0.739843356793082	ST8SIA4	1
GO:1903206	negative regulation of hydrogen peroxide-induced cell death	1/896	20/18722	0.625189685273139	0.739843356793082	LRRK2	1
GO:1903817	negative regulation of voltage-gated potassium channel activity	1/896	20/18722	0.625189685273139	0.739843356793082	KCNE3	1
GO:1904263	positive regulation of TORC1 signaling	1/896	20/18722	0.625189685273139	0.739843356793082	WAC	1
GO:1904292	regulation of ERAD pathway	1/896	20/18722	0.625189685273139	0.739843356793082	HERPUD1	1
GO:2000678	negative regulation of transcription regulatory region DNA binding	1/896	20/18722	0.625189685273139	0.739843356793082	TMSB4X	1
GO:2000757	negative regulation of peptidyl-lysine acetylation	1/896	20/18722	0.625189685273139	0.739843356793082	SPI1	1
GO:0048814	regulation of dendrite morphogenesis	3/896	67/18722	0.628057347359756	0.743067848866718	ACTR2/DBNL/PPP3CA	3
GO:0007626	locomotory behavior	8/896	179/18722	0.628857100274439	0.74333168769081	LRRK2/EGR1/ARRB2/NR4A2/PPT1/AGTPBP1/CSTB/PTEN	8
GO:0002066	columnar/cuboidal epithelial cell development	2/896	44/18722	0.629137875257632	0.74333168769081	CDKN1A/HIF1A	2
GO:0006378	mRNA polyadenylation	2/896	44/18722	0.629137875257632	0.74333168769081	PABPC1/PCF11	2
GO:0006775	fat-soluble vitamin metabolic process	2/896	44/18722	0.629137875257632	0.74333168769081	TNF/NFKB1	2
GO:0032007	negative regulation of TOR signaling	2/896	44/18722	0.629137875257632	0.74333168769081	HIF1A/ATM	2
GO:0051150	regulation of smooth muscle cell differentiation	2/896	44/18722	0.629137875257632	0.74333168769081	SOD2/PIAS1	2
GO:0015711	organic anion transport	16/896	354/18722	0.629309059710695	0.743365073712315	IL1B/RGS2/SLC2A3/SLC11A1/CD36/PSAP/SLC7A7/SYK/MGST1/SLCO3A1/AQP9/SLC16A3/CYB5R4/MPC1/SLC25A24/EMB	16
GO:0070646	protein modification by small protein removal	7/896	157/18722	0.629658079898356	0.743608463567518	TNFAIP3/USP15/USP3/OTUD1/CYLD/TANK/TAF10	7
GO:0032392	DNA geometric change	4/896	90/18722	0.63046272792181	0.744233359666622	SETX/CHD1/CHD9/DDX3X	4
GO:0018205	peptidyl-lysine modification	17/896	376/18722	0.630616499913633	0.744233359666622	IL1B/SPI1/EGR1/BLOC1S1/KMT2E/ARID4A/IFIH1/PIAS1/MSL3/TET2/PHF20L1/KMT2C/TAF10/CREBBP/EP300/KMT2A/EPC1	17
GO:0044282	small molecule catabolic process	17/896	376/18722	0.630616499913633	0.744233359666622	APOBEC3A/DPYD/ALDH2/SULT1A1/CDA/UPP1/KYNU/GLUL/NAGK/MGAT1/PTEN/PGD/HNMT/NUDT3/DECR1/NQO2/IRS2	17
GO:0009988	cell-cell recognition	3/896	68/18722	0.638075294951993	0.749497068634004	MSN/DOCK2/DOCK8	3
GO:0042698	ovulation cycle	3/896	68/18722	0.638075294951993	0.749497068634004	EGR1/ARRB2/RETN	3
GO:1901016	regulation of potassium ion transmembrane transporter activity	3/896	68/18722	0.638075294951993	0.749497068634004	KCNE3/PTEN/CAB39	3
GO:1904888	cranial skeletal system development	3/896	68/18722	0.638075294951993	0.749497068634004	NIPBL/TGFBR2/FOXN3	3
GO:0098876	vesicle-mediated transport to the plasma membrane	6/896	136/18722	0.638395851541571	0.749497068634004	VAMP5/ACAP2/SORL1/CSK/RAB10/CMTM6	6
GO:0014033	neural crest cell differentiation	4/896	91/18722	0.639127857078501	0.749497068634004	MEF2C/HIF1A/MAPK1/CORO1C	4
GO:0008037	cell recognition	10/896	225/18722	0.639919153895114	0.749497068634004	VCAN/FCN1/MSN/CLEC7A/CD36/PECAM1/DOCK2/CXCR4/DOCK8/EMB	10
GO:0006479	protein methylation	8/896	181/18722	0.641249137193418	0.749497068634004	BTG2/BTG1/KMT2E/ARID4A/TET2/KMT2C/CREBBP/KMT2A	8
GO:0008213	protein alkylation	8/896	181/18722	0.641249137193418	0.749497068634004	BTG2/BTG1/KMT2E/ARID4A/TET2/KMT2C/CREBBP/KMT2A	8
GO:0003197	endocardial cushion development	2/896	45/18722	0.641384507008979	0.749497068634004	TGFBR2/MDM4	2
GO:0003254	regulation of membrane depolarization	2/896	45/18722	0.641384507008979	0.749497068634004	TSPO/LRRK2	2
GO:0006903	vesicle targeting	2/896	45/18722	0.641384507008979	0.749497068634004	CHP1/FAM91A1	2
GO:0010824	regulation of centrosome duplication	2/896	45/18722	0.641384507008979	0.749497068634004	CHMP1B/NUP62	2
GO:0022602	ovulation cycle process	2/896	45/18722	0.641384507008979	0.749497068634004	ARRB2/RETN	2
GO:0031670	cellular response to nutrient	2/896	45/18722	0.641384507008979	0.749497068634004	HMOX1/USF2	2
GO:0032309	icosanoid secretion	2/896	45/18722	0.641384507008979	0.749497068634004	IL1B/SYK	2
GO:0043631	RNA polyadenylation	2/896	45/18722	0.641384507008979	0.749497068634004	PABPC1/PCF11	2
GO:0045910	negative regulation of DNA recombination	2/896	45/18722	0.641384507008979	0.749497068634004	BCL6/SMCHD1	2
GO:0048538	thymus development	2/896	45/18722	0.641384507008979	0.749497068634004	MAFB/MAPK1	2
GO:0048546	digestive tract morphogenesis	2/896	45/18722	0.641384507008979	0.749497068634004	HIF1A/NIPBL	2
GO:0060421	positive regulation of heart growth	2/896	45/18722	0.641384507008979	0.749497068634004	MEF2C/MAPK1	2
GO:0003091	renal water homeostasis	1/896	21/18722	0.643146590523661	0.749497068634004	PRKACA	1
GO:0007063	regulation of sister chromatid cohesion	1/896	21/18722	0.643146590523661	0.749497068634004	RB1	1
GO:0007617	mating behavior	1/896	21/18722	0.643146590523661	0.749497068634004	PTEN	1
GO:0008090	retrograde axonal transport	1/896	21/18722	0.643146590523661	0.749497068634004	AGTPBP1	1
GO:0010766	negative regulation of sodium ion transport	1/896	21/18722	0.643146590523661	0.749497068634004	WNK1	1
GO:0010878	cholesterol storage	1/896	21/18722	0.643146590523661	0.749497068634004	CD36	1
GO:0010988	regulation of low-density lipoprotein particle clearance	1/896	21/18722	0.643146590523661	0.749497068634004	CSK	1
GO:0016075	rRNA catabolic process	1/896	21/18722	0.643146590523661	0.749497068634004	XRN1	1
GO:0019985	translesion synthesis	1/896	21/18722	0.643146590523661	0.749497068634004	POLK	1
GO:0030449	regulation of complement activation	1/896	21/18722	0.643146590523661	0.749497068634004	IL1B	1
GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	1/896	21/18722	0.643146590523661	0.749497068634004	STX11	1
GO:0031998	regulation of fatty acid beta-oxidation	1/896	21/18722	0.643146590523661	0.749497068634004	IRS2	1
GO:0033762	response to glucagon	1/896	21/18722	0.643146590523661	0.749497068634004	CREB1	1
GO:0034035	purine ribonucleoside bisphosphate metabolic process	1/896	21/18722	0.643146590523661	0.749497068634004	SULT1A1	1
GO:0035813	regulation of renal sodium excretion	1/896	21/18722	0.643146590523661	0.749497068634004	GNAI2	1
GO:0039702	viral budding via host ESCRT complex	1/896	21/18722	0.643146590523661	0.749497068634004	CHMP1B	1
GO:0043576	regulation of respiratory gaseous exchange	1/896	21/18722	0.643146590523661	0.749497068634004	NR4A2	1
GO:0044241	lipid digestion	1/896	21/18722	0.643146590523661	0.749497068634004	CD36	1
GO:0046599	regulation of centriole replication	1/896	21/18722	0.643146590523661	0.749497068634004	NUP62	1
GO:0048745	smooth muscle tissue development	1/896	21/18722	0.643146590523661	0.749497068634004	ZFAND5	1
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	1/896	21/18722	0.643146590523661	0.749497068634004	SULT1A1	1
GO:0060445	branching involved in salivary gland morphogenesis	1/896	21/18722	0.643146590523661	0.749497068634004	TNF	1
GO:0060972	left/right pattern formation	1/896	21/18722	0.643146590523661	0.749497068634004	NOTCH2	1
GO:0070584	mitochondrion morphogenesis	1/896	21/18722	0.643146590523661	0.749497068634004	PLEC	1
GO:0072170	metanephric tubule development	1/896	21/18722	0.643146590523661	0.749497068634004	STAT1	1
GO:0072243	metanephric nephron epithelium development	1/896	21/18722	0.643146590523661	0.749497068634004	STAT1	1
GO:0098698	postsynaptic specialization assembly	1/896	21/18722	0.643146590523661	0.749497068634004	PTEN	1
GO:0098719	sodium ion import across plasma membrane	1/896	21/18722	0.643146590523661	0.749497068634004	SLC8A1	1
GO:0098856	intestinal lipid absorption	1/896	21/18722	0.643146590523661	0.749497068634004	CD36	1
GO:0099500	vesicle fusion to plasma membrane	1/896	21/18722	0.643146590523661	0.749497068634004	STX11	1
GO:1900118	negative regulation of execution phase of apoptosis	1/896	21/18722	0.643146590523661	0.749497068634004	PAK2	1
GO:1902259	regulation of delayed rectifier potassium channel activity	1/896	21/18722	0.643146590523661	0.749497068634004	KCNE3	1
GO:2000178	negative regulation of neural precursor cell proliferation	1/896	21/18722	0.643146590523661	0.749497068634004	BTG2	1
GO:2000291	regulation of myoblast proliferation	1/896	21/18722	0.643146590523661	0.749497068634004	MALAT1	1
GO:2000774	positive regulation of cellular senescence	1/896	21/18722	0.643146590523661	0.749497068634004	B2M	1
GO:0048285	organelle fission	22/896	488/18722	0.645140248121236	0.751651978153796	IL1B/DUSP1/LRRK2/FLNA/ACTR2/STAT2/RHOA/HSPA1A/ACTR3/CDC42/PRKAR1A/RB1/NIPBL/ATM/STAG2/CORO1C/HNRNPU/PHIP/CHMP1B/NUP62/ZNF207/DYNC1LI1	22
GO:0007586	digestion	6/896	137/18722	0.645430788163077	0.751653723519069	TYMP/CD36/SNX10/TLR4/SGK1/WNK1	6
GO:0060078	regulation of postsynaptic membrane potential	6/896	137/18722	0.645430788163077	0.751653723519069	LRRK2/ARRB2/MEF2C/PTK2B/PTEN/PPP3CA	6
GO:0061138	morphogenesis of a branching epithelium	8/896	182/18722	0.647356856400314	0.753728007642273	SOCS3/CTSH/CTSZ/TNF/STK4/PAK1/GRB2/TGFBR2	8
GO:0032465	regulation of cytokinesis	4/896	92/18722	0.647659383271441	0.753742772968172	RHOA/CALM2/CDC42/NUP62	4
GO:0034502	protein localization to chromosome	4/896	92/18722	0.647659383271441	0.753742772968172	SPI1/TPP1/RB1/NIPBL	4
GO:0045665	negative regulation of neuron differentiation	3/896	69/18722	0.647902707196528	0.75385726624813	B2M/RHOA/CTDSP1	3
GO:0034968	histone lysine methylation	5/896	115/18722	0.649520981506581	0.755402196962372	KMT2E/ARID4A/TET2/KMT2C/KMT2A	5
GO:0090630	activation of GTPase activity	5/896	115/18722	0.649520981506581	0.755402196962372	GPR65/PTK2B/RHOG/CORO1C/RABGAP1L	5
GO:0007411	axon guidance	10/896	227/18722	0.65088624437055	0.756651622032014	RAC2/VASP/NOTCH2/PLXNC1/FYN/RHOG/DPYSL2/PLXNB2/MYCBP2/EMB	10
GO:0071826	ribonucleoprotein complex subunit organization	10/896	227/18722	0.65088624437055	0.756651622032014	CELF2/SETX/SCAF11/EIF2S3/ADAR/ATM/SF3B1/EIF3K/DICER1/CELF1	10
GO:0000724	double-strand break repair via homologous recombination	6/896	138/18722	0.652382549065852	0.757775431219622	SAMHD1/ACTR2/WAS/SMCHD1/NIPBL/NABP1	6
GO:0010498	proteasomal protein catabolic process	22/896	490/18722	0.652663574469529	0.757775431219622	LRRK2/PSMB9/ARRB2/PSMB8/GPX1/HSPA1A/FBXL5/PSME2/TRIB1/PSME1/GABARAP/PSMB10/SPOPL/PRKACA/SDCBP/UBE2D3/PIAS1/PCBP2/WAC/SPOP/HERPUD1/BIRC2	22
GO:0007019	microtubule depolymerization	2/896	46/18722	0.653309946854217	0.757775431219622	TAOK1/CIB1	2
GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	2/896	46/18722	0.653309946854217	0.757775431219622	JAML/ITGAL	2
GO:0032924	activin receptor signaling pathway	2/896	46/18722	0.653309946854217	0.757775431219622	FKBP1A/TGFBR2	2
GO:0042398	cellular modified amino acid biosynthetic process	2/896	46/18722	0.653309946854217	0.757775431219622	PLSCR1/GCH1	2
GO:0046839	phospholipid dephosphorylation	2/896	46/18722	0.653309946854217	0.757775431219622	INPP5D/PTEN	2
GO:0048701	embryonic cranial skeleton morphogenesis	2/896	46/18722	0.653309946854217	0.757775431219622	NIPBL/TGFBR2	2
GO:0055010	ventricular cardiac muscle tissue morphogenesis	2/896	46/18722	0.653309946854217	0.757775431219622	TGFB1/FKBP1A	2
GO:0070828	heterochromatin organization	2/896	46/18722	0.653309946854217	0.757775431219622	SMCHD1/MBD2	2
GO:0097485	neuron projection guidance	10/896	228/18722	0.656299672784739	0.760560265847858	RAC2/VASP/NOTCH2/PLXNC1/FYN/RHOG/DPYSL2/PLXNB2/MYCBP2/EMB	10
GO:0046942	carboxylic acid transport	12/896	273/18722	0.660055460745422	0.760560265847858	IL1B/RGS2/SLC11A1/CD36/PSAP/SLC7A7/SYK/SLCO3A1/AQP9/SLC16A3/MPC1/EMB	12
GO:0002029	desensitization of G protein-coupled receptor signaling pathway	1/896	22/18722	0.660244106960792	0.760560265847858	ARRB2	1
GO:0002089	lens morphogenesis in camera-type eye	1/896	22/18722	0.660244106960792	0.760560265847858	HIPK1	1
GO:0002320	lymphoid progenitor cell differentiation	1/896	22/18722	0.660244106960792	0.760560265847858	SPI1	1
GO:0006379	mRNA cleavage	1/896	22/18722	0.660244106960792	0.760560265847858	PCF11	1
GO:0009190	cyclic nucleotide biosynthetic process	1/896	22/18722	0.660244106960792	0.760560265847858	ADCY7	1
GO:0009220	pyrimidine ribonucleotide biosynthetic process	1/896	22/18722	0.660244106960792	0.760560265847858	UPP1	1
GO:0016137	glycoside metabolic process	1/896	22/18722	0.660244106960792	0.760560265847858	NAGA	1
GO:0021904	dorsal/ventral neural tube patterning	1/896	22/18722	0.660244106960792	0.760560265847858	PRKACA	1
GO:0022401	negative adaptation of signaling pathway	1/896	22/18722	0.660244106960792	0.760560265847858	ARRB2	1
GO:0030277	maintenance of gastrointestinal epithelium	1/896	22/18722	0.660244106960792	0.760560265847858	TLR4	1
GO:0031281	positive regulation of cyclase activity	1/896	22/18722	0.660244106960792	0.760560265847858	TIMP2	1
GO:0034755	iron ion transmembrane transport	1/896	22/18722	0.660244106960792	0.760560265847858	SLC11A1	1
GO:0035024	negative regulation of Rho protein signal transduction	1/896	22/18722	0.660244106960792	0.760560265847858	BCL6	1
GO:0035357	peroxisome proliferator activated receptor signaling pathway	1/896	22/18722	0.660244106960792	0.760560265847858	RXRA	1
GO:0035809	regulation of urine volume	1/896	22/18722	0.660244106960792	0.760560265847858	GNAI2	1
GO:0042430	indole-containing compound metabolic process	1/896	22/18722	0.660244106960792	0.760560265847858	KYNU	1
GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	1/896	22/18722	0.660244106960792	0.760560265847858	BCL6	1
GO:0043574	peroxisomal transport	1/896	22/18722	0.660244106960792	0.760560265847858	RAB8B	1
GO:0046058	cAMP metabolic process	1/896	22/18722	0.660244106960792	0.760560265847858	ADCY7	1
GO:0052652	cyclic purine nucleotide metabolic process	1/896	22/18722	0.660244106960792	0.760560265847858	ADCY7	1
GO:0055093	response to hyperoxia	1/896	22/18722	0.660244106960792	0.760560265847858	CDKN1A	1
GO:0060343	trabecula formation	1/896	22/18722	0.660244106960792	0.760560265847858	FKBP1A	1
GO:0060563	neuroepithelial cell differentiation	1/896	22/18722	0.660244106960792	0.760560265847858	CEBPB	1
GO:0086012	membrane depolarization during cardiac muscle cell action potential	1/896	22/18722	0.660244106960792	0.760560265847858	SLC8A1	1
GO:0090280	positive regulation of calcium ion import	1/896	22/18722	0.660244106960792	0.760560265847858	CCL3	1
GO:0097164	ammonium ion metabolic process	1/896	22/18722	0.660244106960792	0.760560265847858	HNMT	1
GO:1900120	regulation of receptor binding	1/896	22/18722	0.660244106960792	0.760560265847858	B2M	1
GO:1901032	negative regulation of response to reactive oxygen species	1/896	22/18722	0.660244106960792	0.760560265847858	LRRK2	1
GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	1/896	22/18722	0.660244106960792	0.760560265847858	HMOX1	1
GO:1903035	negative regulation of response to wounding	4/896	94/18722	0.664317513541407	0.76458822713398	TNF/ALOX5/SH2B3/PTEN	4
GO:0001754	eye photoreceptor cell differentiation	2/896	47/18722	0.664916852783502	0.76458822713398	AGTPBP1/STAT3	2
GO:0006998	nuclear envelope organization	2/896	47/18722	0.664916852783502	0.76458822713398	PRKCB/SUN2	2
GO:0032369	negative regulation of lipid transport	2/896	47/18722	0.664916852783502	0.76458822713398	IRS2/NFKB1	2
GO:0043114	regulation of vascular permeability	2/896	47/18722	0.664916852783502	0.76458822713398	TGFB1/PLEC	2
GO:0047496	vesicle transport along microtubule	2/896	47/18722	0.664916852783502	0.76458822713398	BLOC1S1/BLOC1S6	2
GO:0048512	circadian behavior	2/896	47/18722	0.664916852783502	0.76458822713398	EGR1/PTEN	2
GO:0051972	regulation of telomerase activity	2/896	47/18722	0.664916852783502	0.76458822713398	KLF4/MAPK1	2
GO:0000725	recombinational repair	6/896	140/18722	0.666032947456213	0.765702334155563	SAMHD1/ACTR2/WAS/SMCHD1/NIPBL/NABP1	6
GO:0003281	ventricular septum development	3/896	71/18722	0.666983688995201	0.766625893141225	CNTRL/TGFBR2/MDM4	3
GO:0008584	male gonad development	6/896	141/18722	0.672729996708596	0.7724693273983	TNFSF10/FLNA/MGST1/ARID4A/NCOA4/KDM5A	6
GO:0016571	histone methylation	6/896	141/18722	0.672729996708596	0.7724693273983	KMT2E/ARID4A/TET2/KMT2C/CREBBP/KMT2A	6
GO:0032527	protein exit from endoplasmic reticulum	2/896	48/18722	0.676208363793856	0.7724693273983	SORL1/HERPUD1	2
GO:0061647	histone H3-K9 modification	2/896	48/18722	0.676208363793856	0.7724693273983	ARID4A/KMT2A	2
GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	2/896	48/18722	0.676208363793856	0.7724693273983	SDCBP/WAC	2
GO:0035567	non-canonical Wnt signaling pathway	3/896	72/18722	0.676236871945769	0.7724693273983	RNF213/RHOA/CDC42	3
GO:0002082	regulation of oxidative phosphorylation	1/896	23/18722	0.676523319803741	0.7724693273983	RHOA	1
GO:0006541	glutamine metabolic process	1/896	23/18722	0.676523319803741	0.7724693273983	GLUL	1
GO:0006833	water transport	1/896	23/18722	0.676523319803741	0.7724693273983	AQP9	1
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	1/896	23/18722	0.676523319803741	0.7724693273983	PTPN2	1
GO:0016973	poly(A)+ mRNA export from nucleus	1/896	23/18722	0.676523319803741	0.7724693273983	HHEX	1
GO:0018279	protein N-linked glycosylation via asparagine	1/896	23/18722	0.676523319803741	0.7724693273983	MGAT1	1
GO:0023058	adaptation of signaling pathway	1/896	23/18722	0.676523319803741	0.7724693273983	ARRB2	1
GO:0030194	positive regulation of blood coagulation	1/896	23/18722	0.676523319803741	0.7724693273983	CD36	1
GO:0030325	adrenal gland development	1/896	23/18722	0.676523319803741	0.7724693273983	TSPO	1
GO:0031338	regulation of vesicle fusion	1/896	23/18722	0.676523319803741	0.7724693273983	CORO1A	1
GO:0033081	regulation of T cell differentiation in thymus	1/896	23/18722	0.676523319803741	0.7724693273983	PTPN2	1
GO:0034695	response to prostaglandin E	1/896	23/18722	0.676523319803741	0.7724693273983	GNB1	1
GO:0035640	exploration behavior	1/896	23/18722	0.676523319803741	0.7724693273983	LRRK2	1
GO:0035812	renal sodium excretion	1/896	23/18722	0.676523319803741	0.7724693273983	GNAI2	1
GO:0035929	steroid hormone secretion	1/896	23/18722	0.676523319803741	0.7724693273983	RETN	1
GO:0040019	positive regulation of embryonic development	1/896	23/18722	0.676523319803741	0.7724693273983	CFL1	1
GO:0042438	melanin biosynthetic process	1/896	23/18722	0.676523319803741	0.7724693273983	ZEB2	1
GO:0045724	positive regulation of cilium assembly	1/896	23/18722	0.676523319803741	0.7724693273983	CCDC88A	1
GO:0051131	chaperone-mediated protein complex assembly	1/896	23/18722	0.676523319803741	0.7724693273983	HSPA1A	1
GO:0051349	positive regulation of lyase activity	1/896	23/18722	0.676523319803741	0.7724693273983	TIMP2	1
GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	1/896	23/18722	0.676523319803741	0.7724693273983	KCNE3	1
GO:0099590	neurotransmitter receptor internalization	1/896	23/18722	0.676523319803741	0.7724693273983	NUMB	1
GO:1900048	positive regulation of hemostasis	1/896	23/18722	0.676523319803741	0.7724693273983	CD36	1
GO:1904666	regulation of ubiquitin protein ligase activity	1/896	23/18722	0.676523319803741	0.7724693273983	PTEN	1
GO:0046546	development of primary male sexual characteristics	6/896	142/18722	0.679340689820025	0.7755160069697	TNFSF10/FLNA/MGST1/ARID4A/NCOA4/KDM5A	6
GO:0035282	segmentation	4/896	96/18722	0.68043068401443	0.776249174722319	MAFB/LFNG/ABI1/EP300	4
GO:0042632	cholesterol homeostasis	4/896	96/18722	0.68043068401443	0.776249174722319	NPC2/CNBP/LAMTOR1/COMMD9	4
GO:0043648	dicarboxylic acid metabolic process	4/896	96/18722	0.68043068401443	0.776249174722319	KYNU/GLUL/MTHFD2/ME2	4
GO:0032456	endocytic recycling	3/896	73/18722	0.68529871140577	0.781459898711118	ACAP2/SORL1/CMTM6	3
GO:0072089	stem cell proliferation	3/896	73/18722	0.68529871140577	0.781459898711118	PTPRC/ZFP36L1/HNRNPU	3
GO:0007622	rhythmic behavior	2/896	49/18722	0.687188047865551	0.782071124058803	EGR1/PTEN	2
GO:0008038	neuron recognition	2/896	49/18722	0.687188047865551	0.782071124058803	CXCR4/EMB	2
GO:0009395	phospholipid catabolic process	2/896	49/18722	0.687188047865551	0.782071124058803	GPCPD1/PLBD1	2
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	2/896	49/18722	0.687188047865551	0.782071124058803	TGFB1/SDCBP	2
GO:0021695	cerebellar cortex development	2/896	49/18722	0.687188047865551	0.782071124058803	AGTPBP1/MTPN	2
GO:0046605	regulation of centrosome cycle	2/896	49/18722	0.687188047865551	0.782071124058803	CHMP1B/NUP62	2
GO:0051445	regulation of meiotic cell cycle	2/896	49/18722	0.687188047865551	0.782071124058803	DUSP1/PRKAR1A	2
GO:0086009	membrane repolarization	2/896	49/18722	0.687188047865551	0.782071124058803	FLNA/KCNE3	2
GO:1901799	negative regulation of proteasomal protein catabolic process	2/896	49/18722	0.687188047865551	0.782071124058803	SDCBP/WAC	2
GO:0055092	sterol homeostasis	4/896	97/18722	0.688281644030581	0.783144351477368	NPC2/CNBP/LAMTOR1/COMMD9	4
GO:0008544	epidermis development	14/896	324/18722	0.690870332026788	0.783289108749226	TXNIP/ZFP36/CSTA/KLF4/HLA-DRB1/WAS/TNF/ZFP36L1/STK4/ROCK1/FOSL2/ASAH1/YBX1/PLEC	14
GO:0001702	gastrulation with mouth forming second	1/896	24/18722	0.69202335218279	0.783289108749226	ETS2	1
GO:0002021	response to dietary excess	1/896	24/18722	0.69202335218279	0.783289108749226	SORL1	1
GO:0003148	outflow tract septum morphogenesis	1/896	24/18722	0.69202335218279	0.783289108749226	TGFBR2	1
GO:0006582	melanin metabolic process	1/896	24/18722	0.69202335218279	0.783289108749226	ZEB2	1
GO:0006817	phosphate ion transport	1/896	24/18722	0.69202335218279	0.783289108749226	CEBPB	1
GO:0018196	peptidyl-asparagine modification	1/896	24/18722	0.69202335218279	0.783289108749226	MGAT1	1
GO:0018230	peptidyl-L-cysteine S-palmitoylation	1/896	24/18722	0.69202335218279	0.783289108749226	ZDHHC20	1
GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine	1/896	24/18722	0.69202335218279	0.783289108749226	ZDHHC20	1
GO:0030878	thyroid gland development	1/896	24/18722	0.69202335218279	0.783289108749226	MAPK1	1
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	1/896	24/18722	0.69202335218279	0.783289108749226	SULF2	1
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	1/896	24/18722	0.69202335218279	0.783289108749226	PHIP	1
GO:0044062	regulation of excretion	1/896	24/18722	0.69202335218279	0.783289108749226	GNAI2	1
GO:0050820	positive regulation of coagulation	1/896	24/18722	0.69202335218279	0.783289108749226	CD36	1
GO:0051123	RNA polymerase II preinitiation complex assembly	1/896	24/18722	0.69202335218279	0.783289108749226	CREB1	1
GO:0051923	sulfation	1/896	24/18722	0.69202335218279	0.783289108749226	SULT1A1	1
GO:0060571	morphogenesis of an epithelial fold	1/896	24/18722	0.69202335218279	0.783289108749226	HIF1A	1
GO:0071676	negative regulation of mononuclear cell migration	1/896	24/18722	0.69202335218279	0.783289108749226	DUSP1	1
GO:0072530	purine-containing compound transmembrane transport	1/896	24/18722	0.69202335218279	0.783289108749226	AQP9	1
GO:0090343	positive regulation of cell aging	1/896	24/18722	0.69202335218279	0.783289108749226	B2M	1
GO:0120255	olefinic compound biosynthetic process	1/896	24/18722	0.69202335218279	0.783289108749226	EGR1	1
GO:1901984	negative regulation of protein acetylation	1/896	24/18722	0.69202335218279	0.783289108749226	SPI1	1
GO:2000353	positive regulation of endothelial cell apoptotic process	1/896	24/18722	0.69202335218279	0.783289108749226	ITGA4	1
GO:2001026	regulation of endothelial cell chemotaxis	1/896	24/18722	0.69202335218279	0.783289108749226	TMSB4X	1
GO:0055088	lipid homeostasis	7/896	167/18722	0.692761939749394	0.783954492740774	NPC2/CNBP/LAMTOR1/IRS2/DDX3X/COMMD9/USF2	7
GO:0051216	cartilage development	8/896	190/18722	0.694005219850056	0.785019823497204	CD44/TIMP1/MEF2C/TGFBI/TGFB1/SULF2/HIF1A/TGFBR2	8
GO:0099111	microtubule-based transport	8/896	190/18722	0.694005219850056	0.785019823497204	BLOC1S1/AGTPBP1/CDC42/HIF1A/SUN2/BICD2/HNRNPU/BLOC1S6	8
GO:0046470	phosphatidylcholine metabolic process	3/896	74/18722	0.69416966817344	0.785035104190055	LPCAT2/CAPN2/MBOAT7	3
GO:0015849	organic acid transport	13/896	303/18722	0.696461826909112	0.787456078642237	IL1B/RGS2/SLC11A1/CD36/SLC7A7/SYK/AQP9/ACSL1/SLC16A3/MPC1/ACSL4/IRS2/EMB	13
GO:0042572	retinol metabolic process	2/896	50/18722	0.697859853806863	0.788180043354939	CYP1B1/ALDH1A1	2
GO:0043268	positive regulation of potassium ion transport	2/896	50/18722	0.697859853806863	0.788180043354939	FLNA/WNK1	2
GO:0060688	regulation of morphogenesis of a branching structure	2/896	50/18722	0.697859853806863	0.788180043354939	LRRK2/TNF	2
GO:0071709	membrane assembly	2/896	50/18722	0.697859853806863	0.788180043354939	PICALM/PTEN	2
GO:0099054	presynapse assembly	2/896	50/18722	0.697859853806863	0.788180043354939	SDCBP/PTEN	2
GO:0007631	feeding behavior	4/896	99/18722	0.703571160739502	0.79377464196009	FOS/RETN/FYN/STAT3	4
GO:0021549	cerebellum development	4/896	99/18722	0.703571160739502	0.79377464196009	AIF1/AGTPBP1/PAK1/MTPN	4
GO:0001964	startle response	1/896	25/18722	0.706781458742006	0.79377464196009	PTEN	1
GO:0010560	positive regulation of glycoprotein biosynthetic process	1/896	25/18722	0.706781458742006	0.79377464196009	CHP1	1
GO:0010842	retina layer formation	1/896	25/18722	0.706781458742006	0.79377464196009	HIPK1	1
GO:0010954	positive regulation of protein processing	1/896	25/18722	0.706781458742006	0.79377464196009	MYH9	1
GO:0015012	heparan sulfate proteoglycan biosynthetic process	1/896	25/18722	0.706781458742006	0.79377464196009	DSE	1
GO:0015874	norepinephrine transport	1/896	25/18722	0.706781458742006	0.79377464196009	ACTB	1
GO:0032925	regulation of activin receptor signaling pathway	1/896	25/18722	0.706781458742006	0.79377464196009	FKBP1A	1
GO:0044550	secondary metabolite biosynthetic process	1/896	25/18722	0.706781458742006	0.79377464196009	ZEB2	1
GO:0045822	negative regulation of heart contraction	1/896	25/18722	0.706781458742006	0.79377464196009	JAK2	1
GO:0046339	diacylglycerol metabolic process	1/896	25/18722	0.706781458742006	0.79377464196009	DGKZ	1
GO:0046835	carbohydrate phosphorylation	1/896	25/18722	0.706781458742006	0.79377464196009	NAGK	1
GO:0050927	positive regulation of positive chemotaxis	1/896	25/18722	0.706781458742006	0.79377464196009	CXCL8	1
GO:0051291	protein heterooligomerization	1/896	25/18722	0.706781458742006	0.79377464196009	MAT2A	1
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	1/896	25/18722	0.706781458742006	0.79377464196009	CREB1	1
GO:0061436	establishment of skin barrier	1/896	25/18722	0.706781458742006	0.79377464196009	PLEC	1
GO:0062009	secondary palate development	1/896	25/18722	0.706781458742006	0.79377464196009	TGFBR2	1
GO:0070199	establishment of protein localization to chromosome	1/896	25/18722	0.706781458742006	0.79377464196009	NIPBL	1
GO:0071459	protein localization to chromosome, centromeric region	1/896	25/18722	0.706781458742006	0.79377464196009	RB1	1
GO:0072202	cell differentiation involved in metanephros development	1/896	25/18722	0.706781458742006	0.79377464196009	STAT1	1
GO:0072207	metanephric epithelium development	1/896	25/18722	0.706781458742006	0.79377464196009	STAT1	1
GO:1902932	positive regulation of alcohol biosynthetic process	1/896	25/18722	0.706781458742006	0.79377464196009	PTAFR	1
GO:1903792	negative regulation of anion transport	1/896	25/18722	0.706781458742006	0.79377464196009	RGS2	1
GO:1905563	negative regulation of vascular endothelial cell proliferation	1/896	25/18722	0.706781458742006	0.79377464196009	MEF2C	1
GO:2000311	regulation of AMPA receptor activity	1/896	25/18722	0.706781458742006	0.79377464196009	MEF2C	1
GO:0000280	nuclear division	19/896	439/18722	0.707247111284236	0.794126128192857	IL1B/DUSP1/FLNA/ACTR2/RHOA/HSPA1A/ACTR3/CDC42/PRKAR1A/RB1/NIPBL/ATM/STAG2/HNRNPU/PHIP/CHMP1B/NUP62/ZNF207/DYNC1LI1	19
GO:0045104	intermediate filament cytoskeleton organization	2/896	51/18722	0.708228066716767	0.794712874863842	VIM/PLEC	2
GO:0045668	negative regulation of osteoblast differentiation	2/896	51/18722	0.708228066716767	0.794712874863842	TNF/NBR1	2
GO:0050982	detection of mechanical stimulus	2/896	51/18722	0.708228066716767	0.794712874863842	CXCR4/FYN	2
GO:0008652	cellular amino acid biosynthetic process	3/896	76/18722	0.711341922247728	0.797346840002248	DPYD/ALDH1A1/GLUL	3
GO:0009123	nucleoside monophosphate metabolic process	3/896	76/18722	0.711341922247728	0.797346840002248	TYMP/DPYD/UPP1	3
GO:0071426	ribonucleoprotein complex export from nucleus	3/896	76/18722	0.711341922247728	0.797346840002248	NUP214/HHEX/SMG1	3
GO:0086001	cardiac muscle cell action potential	3/896	76/18722	0.711341922247728	0.797346840002248	FLNA/SLC8A1/KCNE3	3
GO:0140115	export across plasma membrane	3/896	76/18722	0.711341922247728	0.797346840002248	SLC8A1/KCNE3/CALM2	3
GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	2/896	52/18722	0.718297266830171	0.802623213439879	TAPBP/BICD2	2
GO:0021545	cranial nerve development	2/896	52/18722	0.718297266830171	0.802623213439879	MAFB/TCIRG1	2
GO:0032206	positive regulation of telomere maintenance	2/896	52/18722	0.718297266830171	0.802623213439879	MAPK1/ATM	2
GO:0035176	social behavior	2/896	52/18722	0.718297266830171	0.802623213439879	CX3CR1/PTEN	2
GO:0045103	intermediate filament-based process	2/896	52/18722	0.718297266830171	0.802623213439879	VIM/PLEC	2
GO:0060071	Wnt signaling pathway, planar cell polarity pathway	2/896	52/18722	0.718297266830171	0.802623213439879	RHOA/CDC42	2
GO:0072132	mesenchyme morphogenesis	2/896	52/18722	0.718297266830171	0.802623213439879	TGFBR2/MDM4	2
GO:0048644	muscle organ morphogenesis	3/896	77/18722	0.719645240726824	0.802623213439879	TGFB1/SERP1/FKBP1A	3
GO:0071166	ribonucleoprotein complex localization	3/896	77/18722	0.719645240726824	0.802623213439879	NUP214/HHEX/SMG1	3
GO:0001556	oocyte maturation	1/896	26/18722	0.720833114781326	0.802623213439879	PTK2B	1
GO:0001573	ganglioside metabolic process	1/896	26/18722	0.720833114781326	0.802623213439879	ST8SIA4	1
GO:0002026	regulation of the force of heart contraction	1/896	26/18722	0.720833114781326	0.802623213439879	SLC8A1	1
GO:0003416	endochondral bone growth	1/896	26/18722	0.720833114781326	0.802623213439879	TGFBR2	1
GO:0006706	steroid catabolic process	1/896	26/18722	0.720833114781326	0.802623213439879	HSD17B11	1
GO:0007214	gamma-aminobutyric acid signaling pathway	1/896	26/18722	0.720833114781326	0.802623213439879	GNAI2	1
GO:0015985	energy coupled proton transport, down electrochemical gradient	1/896	26/18722	0.720833114781326	0.802623213439879	ATP6V1A	1
GO:0015986	ATP synthesis coupled proton transport	1/896	26/18722	0.720833114781326	0.802623213439879	ATP6V1A	1
GO:0018027	peptidyl-lysine dimethylation	1/896	26/18722	0.720833114781326	0.802623213439879	KMT2A	1
GO:0021680	cerebellar Purkinje cell layer development	1/896	26/18722	0.720833114781326	0.802623213439879	AGTPBP1	1
GO:0042537	benzene-containing compound metabolic process	1/896	26/18722	0.720833114781326	0.802623213439879	KYNU	1
GO:0046639	negative regulation of alpha-beta T cell differentiation	1/896	26/18722	0.720833114781326	0.802623213439879	BCL6	1
GO:0046755	viral budding	1/896	26/18722	0.720833114781326	0.802623213439879	CHMP1B	1
GO:0048499	synaptic vesicle membrane organization	1/896	26/18722	0.720833114781326	0.802623213439879	STX11	1
GO:0048668	collateral sprouting	1/896	26/18722	0.720833114781326	0.802623213439879	NIN	1
GO:0050926	regulation of positive chemotaxis	1/896	26/18722	0.720833114781326	0.802623213439879	CXCL8	1
GO:0051560	mitochondrial calcium ion homeostasis	1/896	26/18722	0.720833114781326	0.802623213439879	MICU1	1
GO:0072273	metanephric nephron morphogenesis	1/896	26/18722	0.720833114781326	0.802623213439879	STAT1	1
GO:0097186	amelogenesis	1/896	26/18722	0.720833114781326	0.802623213439879	TCIRG1	1
GO:1903523	negative regulation of blood circulation	1/896	26/18722	0.720833114781326	0.802623213439879	JAK2	1
GO:1905063	regulation of vascular associated smooth muscle cell differentiation	1/896	26/18722	0.720833114781326	0.802623213439879	SOD2	1
GO:2000050	regulation of non-canonical Wnt signaling pathway	1/896	26/18722	0.720833114781326	0.802623213439879	RNF213	1
GO:0006672	ceramide metabolic process	4/896	102/18722	0.725475271924618	0.807446370485757	SPTLC2/ST8SIA4/ASAH1/NAGA	4
GO:1990542	mitochondrial transmembrane transport	4/896	102/18722	0.725475271924618	0.807446370485757	UCP2/MPC1/TOMM7/MICU1	4
GO:0034637	cellular carbohydrate biosynthetic process	3/896	78/18722	0.727761689635273	0.809816935034016	FBP1/CSGALNACT2/IRS2	3
GO:0001541	ovarian follicle development	2/896	53/18722	0.728072291524526	0.809816935034016	ARRB2/CEBPB	2
GO:0051438	regulation of ubiquitin-protein transferase activity	2/896	53/18722	0.728072291524526	0.809816935034016	DTX3L/PTEN	2
GO:0003279	cardiac septum development	4/896	103/18722	0.7325030755487	0.811612569199395	NOTCH2/CNTRL/TGFBR2/MDM4	4
GO:0019395	fatty acid oxidation	4/896	103/18722	0.7325030755487	0.811612569199395	PDK4/PRKAG2/DECR1/IRS2	4
GO:0000737	DNA catabolic process, endonucleolytic	1/896	27/18722	0.734212101150385	0.811612569199395	DICER1	1
GO:0001958	endochondral ossification	1/896	27/18722	0.734212101150385	0.811612569199395	MEF2C	1
GO:0003272	endocardial cushion formation	1/896	27/18722	0.734212101150385	0.811612569199395	TGFBR2	1
GO:0006783	heme biosynthetic process	1/896	27/18722	0.734212101150385	0.811612569199395	TSPO	1
GO:0010528	regulation of transposition	1/896	27/18722	0.734212101150385	0.811612569199395	APOBEC3A	1
GO:0010529	negative regulation of transposition	1/896	27/18722	0.734212101150385	0.811612569199395	APOBEC3A	1
GO:0010561	negative regulation of glycoprotein biosynthetic process	1/896	27/18722	0.734212101150385	0.811612569199395	HBEGF	1
GO:0010894	negative regulation of steroid biosynthetic process	1/896	27/18722	0.734212101150385	0.811612569199395	NFKB1	1
GO:0018126	protein hydroxylation	1/896	27/18722	0.734212101150385	0.811612569199395	CRTAP	1
GO:0032781	positive regulation of ATPase activity	1/896	27/18722	0.734212101150385	0.811612569199395	PFN1	1
GO:0033561	regulation of water loss via skin	1/896	27/18722	0.734212101150385	0.811612569199395	PLEC	1
GO:0033688	regulation of osteoblast proliferation	1/896	27/18722	0.734212101150385	0.811612569199395	RHOA	1
GO:0034377	plasma lipoprotein particle assembly	1/896	27/18722	0.734212101150385	0.811612569199395	PRKACA	1
GO:0034505	tooth mineralization	1/896	27/18722	0.734212101150385	0.811612569199395	TCIRG1	1
GO:0035235	ionotropic glutamate receptor signaling pathway	1/896	27/18722	0.734212101150385	0.811612569199395	PTK2B	1
GO:0035459	vesicle cargo loading	1/896	27/18722	0.734212101150385	0.811612569199395	PICALM	1
GO:0036075	replacement ossification	1/896	27/18722	0.734212101150385	0.811612569199395	MEF2C	1
GO:0042104	positive regulation of activated T cell proliferation	1/896	27/18722	0.734212101150385	0.811612569199395	PYCARD	1
GO:0042403	thyroid hormone metabolic process	1/896	27/18722	0.734212101150385	0.811612569199395	CTSB	1
GO:0046337	phosphatidylethanolamine metabolic process	1/896	27/18722	0.734212101150385	0.811612569199395	NAAA	1
GO:0048520	positive regulation of behavior	1/896	27/18722	0.734212101150385	0.811612569199395	MEF2C	1
GO:0051953	negative regulation of amine transport	1/896	27/18722	0.734212101150385	0.811612569199395	RGS2	1
GO:0060512	prostate gland morphogenesis	1/896	27/18722	0.734212101150385	0.811612569199395	CRIP1	1
GO:0070861	regulation of protein exit from endoplasmic reticulum	1/896	27/18722	0.734212101150385	0.811612569199395	SORL1	1
GO:0099625	ventricular cardiac muscle cell membrane repolarization	1/896	27/18722	0.734212101150385	0.811612569199395	KCNE3	1
GO:1903205	regulation of hydrogen peroxide-induced cell death	1/896	27/18722	0.734212101150385	0.811612569199395	LRRK2	1
GO:1903319	positive regulation of protein maturation	1/896	27/18722	0.734212101150385	0.811612569199395	MYH9	1
GO:0006261	DNA-dependent DNA replication	6/896	151/18722	0.734877375925325	0.812002811172215	SAMHD1/BCL6/BAZ1A/FAM111A/BOD1L1/DDX21	6
GO:0048754	branching morphogenesis of an epithelial tube	6/896	151/18722	0.734877375925325	0.812002811172215	CTSH/CTSZ/TNF/STK4/PAK1/TGFBR2	6
GO:0006029	proteoglycan metabolic process	3/896	79/18722	0.735692741671741	0.812731085266509	SULF2/CSGALNACT2/DSE	3
GO:0008406	gonad development	9/896	221/18722	0.736025567815958	0.812926094332299	TNFSF10/FLNA/ARRB2/RETN/CEBPB/MGST1/ARID4A/NCOA4/KDM5A	9
GO:0014888	striated muscle adaptation	2/896	54/18722	0.737558200280027	0.813927477117848	CFLAR/PPP3CA	2
GO:0051703	biological process involved in intraspecies interaction between organisms	2/896	54/18722	0.737558200280027	0.813927477117848	CX3CR1/PTEN	2
GO:0060350	endochondral bone morphogenesis	2/896	54/18722	0.737558200280027	0.813927477117848	MEF2C/TGFBR2	2
GO:0086002	cardiac muscle cell action potential involved in contraction	2/896	54/18722	0.737558200280027	0.813927477117848	FLNA/KCNE3	2
GO:0050954	sensory perception of mechanical stimulus	7/896	175/18722	0.737936508594109	0.814172206448443	GPX1/CXCR4/MBP/FYN/DIAPH1/NIPBL/PPIP5K2	7
GO:1901264	carbohydrate derivative transport	3/896	80/18722	0.743440030071577	0.820070327975032	PSAP/NPC2/SLC25A24	3
GO:0001755	neural crest cell migration	2/896	55/18722	0.746760242398206	0.821156202300986	HIF1A/CORO1C	2
GO:0003229	ventricular cardiac muscle tissue development	2/896	55/18722	0.746760242398206	0.821156202300986	TGFB1/FKBP1A	2
GO:0042220	response to cocaine	2/896	55/18722	0.746760242398206	0.821156202300986	PTK2B/HNMT	2
GO:0044091	membrane biogenesis	2/896	55/18722	0.746760242398206	0.821156202300986	PICALM/PTEN	2
GO:0001945	lymph vessel development	1/896	28/18722	0.74695058509632	0.821156202300986	SYK	1
GO:0006516	glycoprotein catabolic process	1/896	28/18722	0.74695058509632	0.821156202300986	CST3	1
GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	1/896	28/18722	0.74695058509632	0.821156202300986	DGKZ	1
GO:0009065	glutamine family amino acid catabolic process	1/896	28/18722	0.74695058509632	0.821156202300986	GLUL	1
GO:0009312	oligosaccharide biosynthetic process	1/896	28/18722	0.74695058509632	0.821156202300986	FBP1	1
GO:0010460	positive regulation of heart rate	1/896	28/18722	0.74695058509632	0.821156202300986	GCH1	1
GO:0030262	apoptotic nuclear changes	1/896	28/18722	0.74695058509632	0.821156202300986	DICER1	1
GO:0031440	regulation of mRNA 3'-end processing	1/896	28/18722	0.74695058509632	0.821156202300986	ZFP36L1	1
GO:0051503	adenine nucleotide transport	1/896	28/18722	0.74695058509632	0.821156202300986	SLC25A24	1
GO:0062125	regulation of mitochondrial gene expression	1/896	28/18722	0.74695058509632	0.821156202300986	CHCHD10	1
GO:0071280	cellular response to copper ion	1/896	28/18722	0.74695058509632	0.821156202300986	PRNP	1
GO:1903020	positive regulation of glycoprotein metabolic process	1/896	28/18722	0.74695058509632	0.821156202300986	CHP1	1
GO:0043414	macromolecule methylation	13/896	316/18722	0.750810785151436	0.824742135219248	FOS/SPI1/BTG2/KDM1B/BTG1/TRMT1/KMT2E/ARID4A/TET2/MBD2/KMT2C/CREBBP/KMT2A	13
GO:0001523	retinoid metabolic process	3/896	81/18722	0.751005335973536	0.824742135219248	CYP1B1/SCPEP1/ALDH1A1	3
GO:0008589	regulation of smoothened signaling pathway	3/896	81/18722	0.751005335973536	0.824742135219248	PRKACA/RB1/CREBBP	3
GO:0014032	neural crest cell development	3/896	81/18722	0.751005335973536	0.824742135219248	HIF1A/MAPK1/CORO1C	3
GO:2000243	positive regulation of reproductive process	3/896	81/18722	0.751005335973536	0.824742135219248	RETN/PTAFR/CIB1	3
GO:0009952	anterior/posterior pattern specification	8/896	201/18722	0.751399354665755	0.825000642519863	BTG2/LFNG/HHEX/ATP6AP2/ABI1/HIPK1/ETS2/EP300	8
GO:0006687	glycosphingolipid metabolic process	2/896	56/18722	0.755683827295649	0.828560847480866	ST8SIA4/NAGA	2
GO:0030166	proteoglycan biosynthetic process	2/896	56/18722	0.755683827295649	0.828560847480866	CSGALNACT2/DSE	2
GO:0055078	sodium ion homeostasis	2/896	56/18722	0.755683827295649	0.828560847480866	GNAI2/SLC8A1	2
GO:0090175	regulation of establishment of planar polarity	2/896	56/18722	0.755683827295649	0.828560847480866	RHOA/CDC42	2
GO:0018022	peptidyl-lysine methylation	5/896	131/18722	0.757122912181678	0.828560847480866	KMT2E/ARID4A/TET2/KMT2C/KMT2A	5
GO:0008543	fibroblast growth factor receptor signaling pathway	3/896	82/18722	0.758390576335215	0.828560847480866	SULF2/SETX/SHOC2	3
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	3/896	82/18722	0.758390576335215	0.828560847480866	RNASET2/NUDT16/DICER1	3
GO:0015980	energy derivation by oxidation of organic compounds	13/896	318/18722	0.758564868046631	0.828560847480866	SCO2/BID/RHOA/BLOC1S1/PRKAG2/CHCHD10/HIF1A/PYGL/OXA1L/IRS2/PLEC/RB1CC1/IFNAR1	13
GO:0003209	cardiac atrium morphogenesis	1/896	29/18722	0.759079197258174	0.828560847480866	NOTCH2	1
GO:0005979	regulation of glycogen biosynthetic process	1/896	29/18722	0.759079197258174	0.828560847480866	IRS2	1
GO:0006656	phosphatidylcholine biosynthetic process	1/896	29/18722	0.759079197258174	0.828560847480866	CAPN2	1
GO:0006688	glycosphingolipid biosynthetic process	1/896	29/18722	0.759079197258174	0.828560847480866	ST8SIA4	1
GO:0007143	female meiotic nuclear division	1/896	29/18722	0.759079197258174	0.828560847480866	PRKAR1A	1
GO:0010962	regulation of glucan biosynthetic process	1/896	29/18722	0.759079197258174	0.828560847480866	IRS2	1
GO:0015701	bicarbonate transport	1/896	29/18722	0.759079197258174	0.828560847480866	CYB5R4	1
GO:0015868	purine ribonucleotide transport	1/896	29/18722	0.759079197258174	0.828560847480866	SLC25A24	1
GO:0019433	triglyceride catabolic process	1/896	29/18722	0.759079197258174	0.828560847480866	SORL1	1
GO:0021602	cranial nerve morphogenesis	1/896	29/18722	0.759079197258174	0.828560847480866	MAFB	1
GO:0030970	retrograde protein transport, ER to cytosol	1/896	29/18722	0.759079197258174	0.828560847480866	HERPUD1	1
GO:0032372	negative regulation of sterol transport	1/896	29/18722	0.759079197258174	0.828560847480866	NFKB1	1
GO:0032375	negative regulation of cholesterol transport	1/896	29/18722	0.759079197258174	0.828560847480866	NFKB1	1
GO:0035066	positive regulation of histone acetylation	1/896	29/18722	0.759079197258174	0.828560847480866	IL1B	1
GO:0070198	protein localization to chromosome, telomeric region	1/896	29/18722	0.759079197258174	0.828560847480866	TPP1	1
GO:0070979	protein K11-linked ubiquitination	1/896	29/18722	0.759079197258174	0.828560847480866	UBE2D3	1
GO:0098868	bone growth	1/896	29/18722	0.759079197258174	0.828560847480866	TGFBR2	1
GO:1900117	regulation of execution phase of apoptosis	1/896	29/18722	0.759079197258174	0.828560847480866	PAK2	1
GO:1903513	endoplasmic reticulum to cytosol transport	1/896	29/18722	0.759079197258174	0.828560847480866	HERPUD1	1
GO:0006325	chromatin organization	17/896	409/18722	0.759163990829265	0.828560847480866	ACTB/IKZF1/SMCHD1/BAZ1A/PAK1/BAZ2B/KMT2E/KDM6B/RB1/CHD9/ZBTB7A/MBD2/ARID1A/HNRNPU/NR3C1/ARID4B/KDM5A	17
GO:0006275	regulation of DNA replication	4/896	107/18722	0.759261872542551	0.828560847480866	CCDC88A/BCL6/JUN/CDC42	4
GO:0032259	methylation	15/896	364/18722	0.760205844353234	0.829416949125482	FOS/SPI1/BTG2/KDM1B/METTL9/BTG1/TRMT1/KMT2E/HNMT/ARID4A/TET2/MBD2/KMT2C/CREBBP/KMT2A	15
GO:0045137	development of primary sexual characteristics	9/896	227/18722	0.763762635036199	0.833122790441122	TNFSF10/FLNA/ARRB2/RETN/CEBPB/MGST1/ARID4A/NCOA4/KDM5A	9
GO:0006695	cholesterol biosynthetic process	2/896	57/18722	0.76433449720073	0.833222326543911	G6PD/LBR	2
GO:0050891	multicellular organismal water homeostasis	2/896	57/18722	0.76433449720073	0.833222326543911	PRKACA/PLEC	2
GO:1902653	secondary alcohol biosynthetic process	2/896	57/18722	0.76433449720073	0.833222326543911	G6PD/LBR	2
GO:0061053	somite development	3/896	83/18722	0.765597792387587	0.833921825535731	LFNG/ABI1/EP300	3
GO:0022037	metencephalon development	4/896	108/18722	0.765617519118077	0.833921825535731	AIF1/AGTPBP1/PAK1/MTPN	4
GO:0098659	inorganic cation import across plasma membrane	4/896	108/18722	0.765617519118077	0.833921825535731	SLC8A1/FYN/PRNP/WNK1	4
GO:0099587	inorganic ion import across plasma membrane	4/896	108/18722	0.765617519118077	0.833921825535731	SLC8A1/FYN/PRNP/WNK1	4
GO:0000132	establishment of mitotic spindle orientation	1/896	30/18722	0.770627104991373	0.835180573673709	DYNLT1	1
GO:0003299	muscle hypertrophy in response to stress	1/896	30/18722	0.770627104991373	0.835180573673709	PPP3CA	1
GO:0006221	pyrimidine nucleotide biosynthetic process	1/896	30/18722	0.770627104991373	0.835180573673709	UPP1	1
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	1/896	30/18722	0.770627104991373	0.835180573673709	DICER1	1
GO:0008209	androgen metabolic process	1/896	30/18722	0.770627104991373	0.835180573673709	HSD17B11	1
GO:0009072	aromatic amino acid family metabolic process	1/896	30/18722	0.770627104991373	0.835180573673709	KYNU	1
GO:0010669	epithelial structure maintenance	1/896	30/18722	0.770627104991373	0.835180573673709	TLR4	1
GO:0014887	cardiac muscle adaptation	1/896	30/18722	0.770627104991373	0.835180573673709	PPP3CA	1
GO:0014898	cardiac muscle hypertrophy in response to stress	1/896	30/18722	0.770627104991373	0.835180573673709	PPP3CA	1
GO:0015721	bile acid and bile salt transport	1/896	30/18722	0.770627104991373	0.835180573673709	AQP9	1
GO:0015865	purine nucleotide transport	1/896	30/18722	0.770627104991373	0.835180573673709	SLC25A24	1
GO:0019674	NAD metabolic process	1/896	30/18722	0.770627104991373	0.835180573673709	NADK	1
GO:0034508	centromere complex assembly	1/896	30/18722	0.770627104991373	0.835180573673709	RB1	1
GO:0034694	response to prostaglandin	1/896	30/18722	0.770627104991373	0.835180573673709	GNB1	1
GO:0036258	multivesicular body assembly	1/896	30/18722	0.770627104991373	0.835180573673709	CHMP1B	1
GO:0044788	modulation by host of viral process	1/896	30/18722	0.770627104991373	0.835180573673709	CFL1	1
GO:0045939	negative regulation of steroid metabolic process	1/896	30/18722	0.770627104991373	0.835180573673709	NFKB1	1
GO:0045940	positive regulation of steroid metabolic process	1/896	30/18722	0.770627104991373	0.835180573673709	TNF	1
GO:0048240	sperm capacitation	1/896	30/18722	0.770627104991373	0.835180573673709	PRKACA	1
GO:0060351	cartilage development involved in endochondral bone morphogenesis	1/896	30/18722	0.770627104991373	0.835180573673709	TGFBR2	1
GO:0060603	mammary gland duct morphogenesis	1/896	30/18722	0.770627104991373	0.835180573673709	CSF1R	1
GO:0061384	heart trabecula morphogenesis	1/896	30/18722	0.770627104991373	0.835180573673709	FKBP1A	1
GO:0090151	establishment of protein localization to mitochondrial membrane	1/896	30/18722	0.770627104991373	0.835180573673709	OXA1L	1
GO:0099068	postsynapse assembly	1/896	30/18722	0.770627104991373	0.835180573673709	PTEN	1
GO:0006821	chloride transport	4/896	109/18722	0.771841485211206	0.836148211744112	TSPO/PTAFR/CLIC1/PRNP	4
GO:0032410	negative regulation of transporter activity	4/896	109/18722	0.771841485211206	0.836148211744112	KCNE3/CALM2/PTEN/CAB39	4
GO:0015844	monoamine transport	3/896	84/18722	0.772629138617964	0.836574897747596	ACTB/LILRB1/SYK	3
GO:0009161	ribonucleoside monophosphate metabolic process	2/896	58/18722	0.772717902091799	0.836574897747596	DPYD/UPP1	2
GO:0010559	regulation of glycoprotein biosynthetic process	2/896	58/18722	0.772717902091799	0.836574897747596	HBEGF/CHP1	2
GO:0001508	action potential	5/896	134/18722	0.774248634571871	0.838057679169261	FLNA/CD36/SLC8A1/KCNE3/GNAQ	5
GO:0048863	stem cell differentiation	8/896	206/18722	0.774838847586063	0.838522023781755	PTPRC/ZFP36L2/MEF2C/STAT3/HIF1A/MAPK1/CORO1C/HNRNPU	8
GO:0045333	cellular respiration	9/896	230/18722	0.776834820036957	0.840507156025008	SCO2/BID/RHOA/BLOC1S1/CHCHD10/HIF1A/OXA1L/PLEC/IFNAR1	9
GO:0032200	telomere organization	6/896	159/18722	0.778208115333947	0.841817888488323	SP100/MAPK1/ATM/HNRNPU/XRN1/SMG1	6
GO:0071806	protein transmembrane transport	2/896	59/18722	0.780839776725234	0.8425319066335	MCL1/TOMM7	2
GO:2001258	negative regulation of cation channel activity	2/896	59/18722	0.780839776725234	0.8425319066335	KCNE3/CALM2	2
GO:0006301	postreplication repair	1/896	31/18722	0.781622082197008	0.8425319066335	POLK	1
GO:0006613	cotranslational protein targeting to membrane	1/896	31/18722	0.781622082197008	0.8425319066335	SSR1	1
GO:0006779	porphyrin-containing compound biosynthetic process	1/896	31/18722	0.781622082197008	0.8425319066335	TSPO	1
GO:0007190	activation of adenylate cyclase activity	1/896	31/18722	0.781622082197008	0.8425319066335	CAP1	1
GO:0018200	peptidyl-glutamic acid modification	1/896	31/18722	0.781622082197008	0.8425319066335	AGTPBP1	1
GO:0033014	tetrapyrrole biosynthetic process	1/896	31/18722	0.781622082197008	0.8425319066335	TSPO	1
GO:0035115	embryonic forelimb morphogenesis	1/896	31/18722	0.781622082197008	0.8425319066335	NIPBL	1
GO:0036474	cell death in response to hydrogen peroxide	1/896	31/18722	0.781622082197008	0.8425319066335	LRRK2	1
GO:0050482	arachidonic acid secretion	1/896	31/18722	0.781622082197008	0.8425319066335	SYK	1
GO:0051443	positive regulation of ubiquitin-protein transferase activity	1/896	31/18722	0.781622082197008	0.8425319066335	PTEN	1
GO:0065005	protein-lipid complex assembly	1/896	31/18722	0.781622082197008	0.8425319066335	PRKACA	1
GO:0070633	transepithelial transport	1/896	31/18722	0.781622082197008	0.8425319066335	ACTB	1
GO:0071711	basement membrane organization	1/896	31/18722	0.781622082197008	0.8425319066335	CTSS	1
GO:0090183	regulation of kidney development	1/896	31/18722	0.781622082197008	0.8425319066335	STAT1	1
GO:1903963	arachidonate transport	1/896	31/18722	0.781622082197008	0.8425319066335	SYK	1
GO:0006338	chromatin remodeling	10/896	255/18722	0.783279946201076	0.844144011643555	ACTB/BAZ1A/PAK1/BAZ2B/KDM6B/RB1/ZBTB7A/MBD2/ARID1A/KDM5A	10
GO:0072073	kidney epithelium development	5/896	136/18722	0.785142576622735	0.845976080591432	STAT1/MEF2C/PECAM1/IQGAP1/NOTCH2	5
GO:0014031	mesenchymal cell development	3/896	86/18722	0.7861733433482	0.846911259062549	HIF1A/MAPK1/CORO1C	3
GO:0055008	cardiac muscle tissue morphogenesis	2/896	60/18722	0.788705919611054	0.849463551024455	TGFB1/FKBP1A	2
GO:0008203	cholesterol metabolic process	5/896	137/18722	0.790434689821964	0.850818480969042	NPC2/APOBR/G6PD/RXRA/LBR	5
GO:0003338	metanephros morphogenesis	1/896	32/18722	0.792090575822361	0.850818480969042	STAT1	1
GO:0008156	negative regulation of DNA replication	1/896	32/18722	0.792090575822361	0.850818480969042	BCL6	1
GO:0030431	sleep	1/896	32/18722	0.792090575822361	0.850818480969042	FOS	1
GO:0032196	transposition	1/896	32/18722	0.792090575822361	0.850818480969042	APOBEC3A	1
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	1/896	32/18722	0.792090575822361	0.850818480969042	HNRNPU	1
GO:0042044	fluid transport	1/896	32/18722	0.792090575822361	0.850818480969042	AQP9	1
GO:0042744	hydrogen peroxide catabolic process	1/896	32/18722	0.792090575822361	0.850818480969042	GPX1	1
GO:0046475	glycerophospholipid catabolic process	1/896	32/18722	0.792090575822361	0.850818480969042	GPCPD1	1
GO:0060317	cardiac epithelial to mesenchymal transition	1/896	32/18722	0.792090575822361	0.850818480969042	TGFBR2	1
GO:0060914	heart formation	1/896	32/18722	0.792090575822361	0.850818480969042	MEF2C	1
GO:0072337	modified amino acid transport	1/896	32/18722	0.792090575822361	0.850818480969042	MGST1	1
GO:1901532	regulation of hematopoietic progenitor cell differentiation	1/896	32/18722	0.792090575822361	0.850818480969042	SPI1	1
GO:0016101	diterpenoid metabolic process	3/896	87/18722	0.792690985115129	0.851111852515232	CYP1B1/SCPEP1/ALDH1A1	3
GO:0150104	transport across blood-brain barrier	3/896	87/18722	0.792690985115129	0.851111852515232	SLC2A3/CD36/SLCO3A1	3
GO:0007224	smoothened signaling pathway	5/896	138/18722	0.795624619925578	0.85398910858303	PRKACA/RB1/TGFBR2/HIPK1/CREBBP	5
GO:0006310	DNA recombination	12/896	305/18722	0.795699138664365	0.85398910858303	PTPRC/SAMHD1/ACTR2/WAS/TGFB1/STAT6/BCL6/SETX/SMCHD1/NIPBL/ATM/NABP1	12
GO:0019748	secondary metabolic process	2/896	61/18722	0.796322173802674	0.854481457798165	ZEB2/CYP1B1	2
GO:0010232	vascular transport	3/896	88/18722	0.79904230506646	0.857223396998899	SLC2A3/CD36/SLCO3A1	3
GO:0006457	protein folding	8/896	212/18722	0.800795207868627	0.858333839004796	CD74/B2M/GRN/PFDN5/FKBP5/HSPA1A/FKBP1A/CRTAP	8
GO:0003382	epithelial cell morphogenesis	1/896	33/18722	0.802057769191177	0.858333839004796	RILPL2	1
GO:0006536	glutamate metabolic process	1/896	33/18722	0.802057769191177	0.858333839004796	GLUL	1
GO:0006654	phosphatidic acid biosynthetic process	1/896	33/18722	0.802057769191177	0.858333839004796	DGKZ	1
GO:0009156	ribonucleoside monophosphate biosynthetic process	1/896	33/18722	0.802057769191177	0.858333839004796	UPP1	1
GO:0010984	regulation of lipoprotein particle clearance	1/896	33/18722	0.802057769191177	0.858333839004796	CSK	1
GO:0032228	regulation of synaptic transmission, GABAergic	1/896	33/18722	0.802057769191177	0.858333839004796	PTEN	1
GO:0040020	regulation of meiotic nuclear division	1/896	33/18722	0.802057769191177	0.858333839004796	PRKAR1A	1
GO:0048730	epidermis morphogenesis	1/896	33/18722	0.802057769191177	0.858333839004796	KLF4	1
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	1/896	33/18722	0.802057769191177	0.858333839004796	CREB1	1
GO:0071763	nuclear membrane organization	1/896	33/18722	0.802057769191177	0.858333839004796	PRKCB	1
GO:1902275	regulation of chromatin organization	1/896	33/18722	0.802057769191177	0.858333839004796	HNRNPU	1
GO:0006260	DNA replication	10/896	260/18722	0.802587200252822	0.858723725265362	SAMHD1/CCDC88A/BCL6/JUN/BAZ1A/FAM111A/CDC42/POLK/BOD1L1/DDX21	10
GO:0046148	pigment biosynthetic process	2/896	62/18722	0.803694409375591	0.859554724072064	TSPO/ZEB2	2
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	2/896	62/18722	0.803694409375591	0.859554724072064	TGFB1/SDCBP	2
GO:0003002	regionalization	13/896	331/18722	0.804963737080691	0.860735278897342	BTG2/MAFB/MEF2C/NOTCH2/LFNG/ITGAM/HHEX/PRKACA/ATP6AP2/ABI1/HIPK1/ETS2/EP300	13
GO:0090305	nucleic acid phosphodiester bond hydrolysis	10/896	261/18722	0.80629178637792	0.861978125580999	ZFP36/SAMHD1/RNASET2/RNASE6/PLSCR1/NUDT16/DICER1/XRN2/PCF11/XRN1	10
GO:0046661	male sex differentiation	6/896	165/18722	0.807046912026153	0.862608094831077	TNFSF10/FLNA/MGST1/ARID4A/NCOA4/KDM5A	6
GO:0001662	behavioral fear response	1/896	34/18722	0.811547642314656	0.865225240803317	MEF2C	1
GO:0006356	regulation of transcription by RNA polymerase I	1/896	34/18722	0.811547642314656	0.865225240803317	FLNA	1
GO:0009649	entrainment of circadian clock	1/896	34/18722	0.811547642314656	0.865225240803317	GNAQ	1
GO:0031128	developmental induction	1/896	34/18722	0.811547642314656	0.865225240803317	HIPK1	1
GO:0042573	retinoic acid metabolic process	1/896	34/18722	0.811547642314656	0.865225240803317	SCPEP1	1
GO:0048854	brain morphogenesis	1/896	34/18722	0.811547642314656	0.865225240803317	PTEN	1
GO:0070050	neuron cellular homeostasis	1/896	34/18722	0.811547642314656	0.865225240803317	TAOK1	1
GO:0086019	cell-cell signaling involved in cardiac conduction	1/896	34/18722	0.811547642314656	0.865225240803317	FLNA	1
GO:2000352	negative regulation of endothelial cell apoptotic process	1/896	34/18722	0.811547642314656	0.865225240803317	TNFAIP3	1
GO:2000758	positive regulation of peptidyl-lysine acetylation	1/896	34/18722	0.811547642314656	0.865225240803317	IL1B	1
GO:0006720	isoprenoid metabolic process	4/896	116/18722	0.811824490505707	0.865225240803317	CYP1B1/NPC2/SCPEP1/ALDH1A1	4
GO:0030326	embryonic limb morphogenesis	4/896	116/18722	0.811824490505707	0.865225240803317	MBNL1/NOTCH2/NIPBL/CREBBP	4
GO:0031123	RNA 3'-end processing	4/896	116/18722	0.811824490505707	0.865225240803317	PABPC1/ZFP36L1/PCF11/LSM10	4
GO:0035113	embryonic appendage morphogenesis	4/896	116/18722	0.811824490505707	0.865225240803317	MBNL1/NOTCH2/NIPBL/CREBBP	4
GO:0043588	skin development	10/896	263/18722	0.813545670453574	0.866881997957189	TXNIP/ZFP36/CSTA/TNF/ZFP36L1/STK4/ROCK1/FOSL2/ASAH1/PLEC	10
GO:0046467	membrane lipid biosynthetic process	5/896	142/18722	0.815380150788575	0.868658780059685	HACD4/SPTLC2/ELOVL5/ST8SIA4/ASAH1	5
GO:0002065	columnar/cuboidal epithelial cell differentiation	3/896	91/18722	0.817124345881035	0.869982338367915	CEBPB/CDKN1A/HIF1A	3
GO:0042147	retrograde transport, endosome to Golgi	3/896	91/18722	0.817124345881035	0.869982338367915	LRRK2/STX10/SNX2	3
GO:0072080	nephron tubule development	3/896	91/18722	0.817124345881035	0.869982338367915	STAT1/MEF2C/NOTCH2	3
GO:0046530	photoreceptor cell differentiation	2/896	64/18722	0.817730345841045	0.870093193273175	AGTPBP1/STAT3	2
GO:0050771	negative regulation of axonogenesis	2/896	64/18722	0.817730345841045	0.870093193273175	ARHGAP4/PTEN	2
GO:1903051	negative regulation of proteolysis involved in cellular protein catabolic process	2/896	64/18722	0.817730345841045	0.870093193273175	SDCBP/WAC	2
GO:0000731	DNA synthesis involved in DNA repair	1/896	35/18722	0.820583029326967	0.871168061957452	POLK	1
GO:0015695	organic cation transport	1/896	35/18722	0.820583029326967	0.871168061957452	SEC14L1	1
GO:0018149	peptide cross-linking	1/896	35/18722	0.820583029326967	0.871168061957452	CSTA	1
GO:0019068	virion assembly	1/896	35/18722	0.820583029326967	0.871168061957452	CHMP1B	1
GO:0033146	regulation of intracellular estrogen receptor signaling pathway	1/896	35/18722	0.820583029326967	0.871168061957452	PAK1	1
GO:0033280	response to vitamin D	1/896	35/18722	0.820583029326967	0.871168061957452	PTGS2	1
GO:0040001	establishment of mitotic spindle localization	1/896	35/18722	0.820583029326967	0.871168061957452	DYNLT1	1
GO:0044273	sulfur compound catabolic process	1/896	35/18722	0.820583029326967	0.871168061957452	GNS	1
GO:0046471	phosphatidylglycerol metabolic process	1/896	35/18722	0.820583029326967	0.871168061957452	LPGAT1	1
GO:0072528	pyrimidine-containing compound biosynthetic process	1/896	35/18722	0.820583029326967	0.871168061957452	UPP1	1
GO:0086005	ventricular cardiac muscle cell action potential	1/896	35/18722	0.820583029326967	0.871168061957452	KCNE3	1
GO:0033692	cellular polysaccharide biosynthetic process	2/896	65/18722	0.824405785652351	0.874155859567355	CSGALNACT2/IRS2	2
GO:0035418	protein localization to synapse	2/896	65/18722	0.824405785652351	0.874155859567355	RAP1A/ADAM10	2
GO:0046503	glycerolipid catabolic process	2/896	65/18722	0.824405785652351	0.874155859567355	GPCPD1/SORL1	2
GO:0061512	protein localization to cilium	2/896	65/18722	0.824405785652351	0.874155859567355	SNX10/CCDC88A	2
GO:1902475	L-alpha-amino acid transmembrane transport	2/896	65/18722	0.824405785652351	0.874155859567355	RGS2/SLC7A7	2
GO:1905330	regulation of morphogenesis of an epithelium	2/896	65/18722	0.824405785652351	0.874155859567355	TNF/ITGAX	2
GO:0060349	bone morphogenesis	3/896	93/18722	0.8283959951812	0.877256852363854	MEF2C/TGFBR2/FOXN3	3
GO:0007031	peroxisome organization	1/896	36/18722	0.829185673182216	0.877256852363854	RAB8B	1
GO:0009225	nucleotide-sugar metabolic process	1/896	36/18722	0.829185673182216	0.877256852363854	MGAT1	1
GO:0010092	specification of animal organ identity	1/896	36/18722	0.829185673182216	0.877256852363854	MEF2C	1
GO:0042755	eating behavior	1/896	36/18722	0.829185673182216	0.877256852363854	STAT3	1
GO:0043949	regulation of cAMP-mediated signaling	1/896	36/18722	0.829185673182216	0.877256852363854	RGS2	1
GO:0044743	protein transmembrane import into intracellular organelle	1/896	36/18722	0.829185673182216	0.877256852363854	TOMM7	1
GO:0051955	regulation of amino acid transport	1/896	36/18722	0.829185673182216	0.877256852363854	RGS2	1
GO:0070873	regulation of glycogen metabolic process	1/896	36/18722	0.829185673182216	0.877256852363854	IRS2	1
GO:0070897	transcription preinitiation complex assembly	1/896	36/18722	0.829185673182216	0.877256852363854	CREB1	1
GO:0086010	membrane depolarization during action potential	1/896	36/18722	0.829185673182216	0.877256852363854	SLC8A1	1
GO:0030193	regulation of blood coagulation	2/896	66/18722	0.830860659684997	0.878671470317542	CD36/SH2B3	2
GO:2000272	negative regulation of signaling receptor activity	2/896	66/18722	0.830860659684997	0.878671470317542	TNF/PTEN	2
GO:0048593	camera-type eye morphogenesis	4/896	120/18722	0.831979468228057	0.879675790659509	NOTCH2/HIF1A/HIPK1/SP3	4
GO:0061326	renal tubule development	3/896	94/18722	0.833805175894599	0.881426975574758	STAT1/MEF2C/NOTCH2	3
GO:0048706	embryonic skeletal system development	4/896	121/18722	0.836727883191574	0.883048260450728	SULF2/NIPBL/TGFBR2/SP3	4
GO:0003016	respiratory system process	1/896	37/18722	0.837376277743317	0.883048260450728	ZFAND5	1
GO:0006862	nucleotide transport	1/896	37/18722	0.837376277743317	0.883048260450728	SLC25A24	1
GO:0030513	positive regulation of BMP signaling pathway	1/896	37/18722	0.837376277743317	0.883048260450728	NOTCH2	1
GO:0033260	nuclear DNA replication	1/896	37/18722	0.837376277743317	0.883048260450728	BCL6	1
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	1/896	37/18722	0.837376277743317	0.883048260450728	SULF2	1
GO:0042178	xenobiotic catabolic process	1/896	37/18722	0.837376277743317	0.883048260450728	ACSL1	1
GO:0046473	phosphatidic acid metabolic process	1/896	37/18722	0.837376277743317	0.883048260450728	DGKZ	1
GO:0048009	insulin-like growth factor receptor signaling pathway	1/896	37/18722	0.837376277743317	0.883048260450728	PHIP	1
GO:0051294	establishment of spindle orientation	1/896	37/18722	0.837376277743317	0.883048260450728	DYNLT1	1
GO:0051567	histone H3-K9 methylation	1/896	37/18722	0.837376277743317	0.883048260450728	ARID4A	1
GO:1905332	positive regulation of morphogenesis of an epithelium	1/896	37/18722	0.837376277743317	0.883048260450728	ITGAX	1
GO:0003007	heart morphogenesis	9/896	246/18722	0.837768836774587	0.883230977317588	FLNA/MEF2C/TGFB1/NOTCH2/FKBP1A/HIF1A/NIPBL/TGFBR2/MDM4	9
GO:1902652	secondary alcohol metabolic process	5/896	147/18722	0.837889183250333	0.883230977317588	NPC2/APOBR/G6PD/RXRA/LBR	5
GO:0008585	female gonad development	3/896	95/18722	0.839067001871566	0.884293308355423	ARRB2/RETN/CEBPB	3
GO:0060411	cardiac septum morphogenesis	2/896	68/18722	0.843131836349688	0.888217273821091	NOTCH2/TGFBR2	2
GO:1900046	regulation of hemostasis	2/896	68/18722	0.843131836349688	0.888217273821091	CD36/SH2B3	2
GO:0048193	Golgi vesicle transport	11/896	296/18722	0.843551399951257	0.888454709005349	LAPTM5/VAMP5/LRRK2/VPS13C/SORL1/CSK/TAPBP/RAB8B/BICD2/RAB10/SNX2	11
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	12/896	320/18722	0.843869690922212	0.888454709005349	PABPC1/MBNL1/CELF2/SETX/SCAF11/DDX5/SF3B1/ZBTB7A/HNRNPU/QKI/CDC40/CELF1	12
GO:0000398	mRNA splicing, via spliceosome	12/896	320/18722	0.843869690922212	0.888454709005349	PABPC1/MBNL1/CELF2/SETX/SCAF11/DDX5/SF3B1/ZBTB7A/HNRNPU/QKI/CDC40/CELF1	12
GO:0015914	phospholipid transport	3/896	96/18722	0.844184302447603	0.888606062948792	NPC2/PLSCR1/OSBPL8	3
GO:0007007	inner mitochondrial membrane organization	1/896	38/18722	0.845174557386988	0.888749064490441	CHCHD10	1
GO:0010719	negative regulation of epithelial to mesenchymal transition	1/896	38/18722	0.845174557386988	0.888749064490441	PTEN	1
GO:0035136	forelimb morphogenesis	1/896	38/18722	0.845174557386988	0.888749064490441	NIPBL	1
GO:0042596	fear response	1/896	38/18722	0.845174557386988	0.888749064490441	MEF2C	1
GO:0071392	cellular response to estradiol stimulus	1/896	38/18722	0.845174557386988	0.888749064490441	CFLAR	1
GO:0022613	ribonucleoprotein complex biogenesis	18/896	463/18722	0.848586502155426	0.891677920409507	CELF2/GLUL/SETX/NUDT16/SCAF11/EIF2S3/PTEN/ADAR/ATM/SF3B1/EIF3K/DICER1/XRN2/CELF1/DDX21/DDX3X/WDR74/RSL24D1	18
GO:0006368	transcription elongation from RNA polymerase II promoter	2/896	69/18722	0.84895957154829	0.891677920409507	ARID1A/HNRNPU	2
GO:0015807	L-amino acid transport	2/896	69/18722	0.84895957154829	0.891677920409507	SLC11A1/SLC7A7	2
GO:0019226	transmission of nerve impulse	2/896	69/18722	0.84895957154829	0.891677920409507	TYMP/PLEC	2
GO:0031060	regulation of histone methylation	2/896	69/18722	0.84895957154829	0.891677920409507	KMT2E/KMT2A	2
GO:0006721	terpenoid metabolic process	3/896	97/18722	0.849159919205593	0.891677920409507	CYP1B1/SCPEP1/ALDH1A1	3
GO:0070252	actin-mediated cell contraction	3/896	97/18722	0.849159919205593	0.891677920409507	FLNA/KCNE3/SHTN1	3
GO:0007368	determination of left/right symmetry	4/896	124/18722	0.850303395980301	0.892698417943792	MEF2C/NOTCH2/HIF1A/TGFBR2	4
GO:0007618	mating	1/896	39/18722	0.852599284243189	0.894386623103837	PTEN	1
GO:0046461	neutral lipid catabolic process	1/896	39/18722	0.852599284243189	0.894386623103837	SORL1	1
GO:0046464	acylglycerol catabolic process	1/896	39/18722	0.852599284243189	0.894386623103837	SORL1	1
GO:0086091	regulation of heart rate by cardiac conduction	1/896	39/18722	0.852599284243189	0.894386623103837	KCNE3	1
GO:0060415	muscle tissue morphogenesis	2/896	70/18722	0.854589589829567	0.896293699678076	TGFB1/FKBP1A	2
GO:0000375	RNA splicing, via transesterification reactions	12/896	324/18722	0.855117219219553	0.896666261524374	PABPC1/MBNL1/CELF2/SETX/SCAF11/DDX5/SF3B1/ZBTB7A/HNRNPU/QKI/CDC40/CELF1	12
GO:0007548	sex differentiation	10/896	276/18722	0.855790626870752	0.897191503800601	TNFSF10/FLNA/ARRB2/RETN/CEBPB/MGST1/ARID4A/NCOA4/NIPBL/KDM5A	10
GO:0009187	cyclic nucleotide metabolic process	1/896	40/18722	0.859668333181695	0.900349375931936	ADCY7	1
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	1/896	40/18722	0.859668333181695	0.900349375931936	CALM2	1
GO:0060412	ventricular septum morphogenesis	1/896	40/18722	0.859668333181695	0.900349375931936	TGFBR2	1
GO:1901020	negative regulation of calcium ion transmembrane transporter activity	1/896	40/18722	0.859668333181695	0.900349375931936	CALM2	1
GO:1901661	quinone metabolic process	1/896	40/18722	0.859668333181695	0.900349375931936	NQO2	1
GO:0050818	regulation of coagulation	2/896	71/18722	0.860027442027665	0.900544136498064	CD36/SH2B3	2
GO:0035270	endocrine system development	4/896	127/18722	0.862911071232723	0.903207023441777	TSPO/IL6R/MAPK1/CREB1	4
GO:0007416	synapse assembly	6/896	179/18722	0.862919498842704	0.903207023441777	MEF2C/TLR2/SDCBP/PTEN/PLXNB2/DBNL	6
GO:0006910	phagocytosis, recognition	3/896	100/18722	0.863265163147294	0.903207023441777	FCN1/CLEC7A/CD36	3
GO:0046545	development of primary female sexual characteristics	3/896	100/18722	0.863265163147294	0.903207023441777	ARRB2/RETN/CEBPB	3
GO:0001736	establishment of planar polarity	2/896	72/18722	0.865278601172862	0.903939772702284	RHOA/CDC42	2
GO:0007164	establishment of tissue polarity	2/896	72/18722	0.865278601172862	0.903939772702284	RHOA/CDC42	2
GO:0042273	ribosomal large subunit biogenesis	2/896	72/18722	0.865278601172862	0.903939772702284	WDR74/RSL24D1	2
GO:0007605	sensory perception of sound	5/896	154/18722	0.865571651352515	0.903939772702284	GPX1/MBP/DIAPH1/NIPBL/PPIP5K2	5
GO:0015698	inorganic anion transport	6/896	180/18722	0.866340673421097	0.903939772702284	TSPO/SLC11A1/CEBPB/PTAFR/CLIC1/PRNP	6
GO:0002251	organ or tissue specific immune response	1/896	41/18722	0.866398724653122	0.903939772702284	IL6R	1
GO:0006418	tRNA aminoacylation for protein translation	1/896	41/18722	0.866398724653122	0.903939772702284	CARS2	1
GO:0007099	centriole replication	1/896	41/18722	0.866398724653122	0.903939772702284	NUP62	1
GO:0030488	tRNA methylation	1/896	41/18722	0.866398724653122	0.903939772702284	TRMT1	1
GO:0044786	cell cycle DNA replication	1/896	41/18722	0.866398724653122	0.903939772702284	BCL6	1
GO:0048286	lung alveolus development	1/896	41/18722	0.866398724653122	0.903939772702284	CREB1	1
GO:0050892	intestinal absorption	1/896	41/18722	0.866398724653122	0.903939772702284	CD36	1
GO:0050913	sensory perception of bitter taste	1/896	41/18722	0.866398724653122	0.903939772702284	PLCB2	1
GO:1902116	negative regulation of organelle assembly	1/896	41/18722	0.866398724653122	0.903939772702284	LRRK2	1
GO:1903509	liposaccharide metabolic process	3/896	101/18722	0.867702536757398	0.905118510564627	AOAH/ST8SIA4/NAGA	3
GO:0090596	sensory organ morphogenesis	9/896	256/18722	0.868727360385468	0.906005815392986	MAFB/NOTCH2/AGTPBP1/STAT3/HIF1A/MAPK1/NIPBL/HIPK1/SP3	9
GO:0051298	centrosome duplication	2/896	73/18722	0.870348457222639	0.907332596916205	CHMP1B/NUP62	2
GO:0086003	cardiac muscle cell contraction	2/896	73/18722	0.870348457222639	0.907332596916205	FLNA/KCNE3	2
GO:0009124	nucleoside monophosphate biosynthetic process	1/896	42/18722	0.872806665486632	0.909530648606686	UPP1	1
GO:0046688	response to copper ion	1/896	42/18722	0.872806665486632	0.909530648606686	PRNP	1
GO:0006352	DNA-templated transcription, initiation	4/896	130/18722	0.874599067287171	0.910850970957264	JUN/SETX/TAF10/CREB1	4
GO:0006956	complement activation	4/896	130/18722	0.874599067287171	0.910850970957264	FCN1/IL1B/CFD/CFP	4
GO:0007098	centrosome cycle	4/896	130/18722	0.874599067287171	0.910850970957264	NIN/PPP1R12A/CHMP1B/NUP62	4
GO:0006635	fatty acid beta-oxidation	2/896	74/18722	0.875242312474006	0.911338391827288	DECR1/IRS2	2
GO:0021983	pituitary gland development	1/896	43/18722	0.878907587741663	0.914422557280334	CREB1	1
GO:0030517	negative regulation of axon extension	1/896	43/18722	0.878907587741663	0.914422557280334	ARHGAP4	1
GO:0042181	ketone biosynthetic process	1/896	43/18722	0.878907587741663	0.914422557280334	EGR1	1
GO:0045494	photoreceptor cell maintenance	1/896	43/18722	0.878907587741663	0.914422557280334	DRAM2	1
GO:1903363	negative regulation of cellular protein catabolic process	2/896	75/18722	0.879965377604076	0.91533998578376	SDCBP/WAC	2
GO:1901890	positive regulation of cell junction assembly	3/896	104/18722	0.880261185053987	0.915464591774802	IQGAP1/ROCK1/LIMS1	3
GO:0021536	diencephalon development	2/896	76/18722	0.884522768289382	0.918811677687505	NR4A2/CREB1	2
GO:0005978	glycogen biosynthetic process	1/896	44/18722	0.884716185706408	0.918811677687505	IRS2	1
GO:0007528	neuromuscular junction development	1/896	44/18722	0.884716185706408	0.918811677687505	LRRK2	1
GO:0009250	glucan biosynthetic process	1/896	44/18722	0.884716185706408	0.918811677687505	IRS2	1
GO:0043039	tRNA aminoacylation	1/896	44/18722	0.884716185706408	0.918811677687505	CARS2	1
GO:0048806	genitalia development	1/896	44/18722	0.884716185706408	0.918811677687505	NIPBL	1
GO:0089718	amino acid import across plasma membrane	1/896	44/18722	0.884716185706408	0.918811677687505	RGS2	1
GO:0006997	nucleus organization	4/896	133/18722	0.885416071774713	0.919171454950156	PRKCB/SUN2/PLEC/CHMP1B	4
GO:0009855	determination of bilateral symmetry	4/896	133/18722	0.885416071774713	0.919171454950156	MEF2C/NOTCH2/HIF1A/TGFBR2	4
GO:0009799	specification of symmetry	4/896	134/18722	0.888836608304031	0.92244020984886	MEF2C/NOTCH2/HIF1A/TGFBR2	4
GO:0006367	transcription initiation from RNA polymerase II promoter	2/896	77/18722	0.888919502357717	0.92244020984886	TAF10/CREB1	2
GO:0043038	amino acid activation	1/896	45/18722	0.890246451131349	0.922896510331702	CARS2	1
GO:0048599	oocyte development	1/896	45/18722	0.890246451131349	0.922896510331702	PTK2B	1
GO:0051180	vitamin transport	1/896	45/18722	0.890246451131349	0.922896510331702	SLC2A3	1
GO:0085029	extracellular matrix assembly	1/896	45/18722	0.890246451131349	0.922896510331702	TGFB1	1
GO:0098534	centriole assembly	1/896	45/18722	0.890246451131349	0.922896510331702	NUP62	1
GO:0042303	molting cycle	3/896	107/18722	0.89174827904134	0.923981462699247	PTGS2/TNF/NIPBL	3
GO:0042633	hair cycle	3/896	107/18722	0.89174827904134	0.923981462699247	PTGS2/TNF/NIPBL	3
GO:0009581	detection of external stimulus	4/896	135/18722	0.892167574162599	0.923981462699247	ARRB2/CXCR4/FYN/GNAQ	4
GO:0042157	lipoprotein metabolic process	4/896	135/18722	0.892167574162599	0.923981462699247	APOL6/PPT1/GLUL/ZDHHC20	4
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	15/896	412/18722	0.892181293150475	0.923981462699247	LRRK2/ARRB2/HSPA1A/FBXL5/TRIB1/GABARAP/SPOPL/SDCBP/UBE2D3/PIAS1/PCBP2/WAC/SPOP/HERPUD1/BIRC2	15
GO:0009064	glutamine family amino acid metabolic process	2/896	78/18722	0.893160497429361	0.924811416908243	SLC7A7/GLUL	2
GO:0009060	aerobic respiration	6/896	189/18722	0.894044976325244	0.925542978078741	BID/RHOA/BLOC1S1/CHCHD10/HIF1A/OXA1L	6
GO:0006813	potassium ion transport	8/896	241/18722	0.895366225189697	0.925771494130974	FLNA/KCNE3/PTK2B/CHP1/PTEN/CAB39/PRNP/WNK1	8
GO:0006383	transcription by RNA polymerase III	1/896	46/18722	0.895511706781952	0.925771494130974	IVNS1ABP	1
GO:0031018	endocrine pancreas development	1/896	46/18722	0.895511706781952	0.925771494130974	IL6R	1
GO:0050919	negative chemotaxis	1/896	46/18722	0.895511706781952	0.925771494130974	RHOA	1
GO:0060976	coronary vasculature development	1/896	46/18722	0.895511706781952	0.925771494130974	CNTRL	1
GO:0071827	plasma lipoprotein particle organization	1/896	46/18722	0.895511706781952	0.925771494130974	PRKACA	1
GO:0090329	regulation of DNA-dependent DNA replication	1/896	46/18722	0.895511706781952	0.925771494130974	BCL6	1
GO:0090090	negative regulation of canonical Wnt signaling pathway	4/896	137/18722	0.898567930826059	0.928746384782657	EGR1/PFDN5/STK4/CYLD	4
GO:0045332	phospholipid translocation	1/896	47/18722	0.900524638390614	0.930029516336295	PLSCR1	1
GO:0050885	neuromuscular process controlling balance	1/896	47/18722	0.900524638390614	0.930029516336295	TPP1	1
GO:1903170	negative regulation of calcium ion transmembrane transport	1/896	47/18722	0.900524638390614	0.930029516336295	CALM2	1
GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	1/896	47/18722	0.900524638390614	0.930029516336295	HMOX1	1
GO:0007422	peripheral nervous system development	2/896	80/18722	0.901194428980196	0.930443282015965	DICER1/PLEC	2
GO:0009582	detection of abiotic stimulus	4/896	138/18722	0.901640865479804	0.930443282015965	ARRB2/CXCR4/FYN/GNAQ	4
GO:0035107	appendage morphogenesis	4/896	138/18722	0.901640865479804	0.930443282015965	MBNL1/NOTCH2/NIPBL/CREBBP	4
GO:0035108	limb morphogenesis	4/896	138/18722	0.901640865479804	0.930443282015965	MBNL1/NOTCH2/NIPBL/CREBBP	4
GO:0009063	cellular amino acid catabolic process	3/896	110/18722	0.902237672073241	0.930874455951781	KYNU/GLUL/HNMT	3
GO:0006814	sodium ion transport	8/896	245/18722	0.904854316733065	0.933388992726829	FXYD5/SLC8A1/KCNE3/GLRX/CHP1/SGK1/COMMD9/WNK1	8
GO:0015804	neutral amino acid transport	1/896	48/18722	0.905297325084162	0.933660794717971	RGS2	1
GO:0007292	female gamete generation	4/896	140/18722	0.907541018407686	0.935603733743979	RGS2/PTGS2/PTK2B/PRKAR1A	4
GO:0015748	organophosphate ester transport	4/896	140/18722	0.907541018407686	0.935603733743979	NPC2/PLSCR1/OSBPL8/SLC25A24	4
GO:2001252	positive regulation of chromosome organization	2/896	82/18722	0.908661837203455	0.936119572054999	MAPK1/ATM	2
GO:0000959	mitochondrial RNA metabolic process	1/896	49/18722	0.90984126835955	0.936119572054999	CHCHD10	1
GO:0007602	phototransduction	1/896	49/18722	0.90984126835955	0.936119572054999	GNAQ	1
GO:0009994	oocyte differentiation	1/896	49/18722	0.90984126835955	0.936119572054999	PTK2B	1
GO:0030195	negative regulation of blood coagulation	1/896	49/18722	0.90984126835955	0.936119572054999	SH2B3	1
GO:0030857	negative regulation of epithelial cell differentiation	1/896	49/18722	0.90984126835955	0.936119572054999	STAT1	1
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1/896	49/18722	0.90984126835955	0.936119572054999	FBXL5	1
GO:0048168	regulation of neuronal synaptic plasticity	1/896	49/18722	0.90984126835955	0.936119572054999	MCTP1	1
GO:0051932	synaptic transmission, GABAergic	1/896	49/18722	0.90984126835955	0.936119572054999	PTEN	1
GO:1990573	potassium ion import across plasma membrane	1/896	49/18722	0.90984126835955	0.936119572054999	WNK1	1
GO:0071825	protein-lipid complex subunit organization	1/896	50/18722	0.914167419676952	0.939857752141151	PRKACA	1
GO:0090102	cochlea development	1/896	50/18722	0.914167419676952	0.939857752141151	ADAM10	1
GO:1900047	negative regulation of hemostasis	1/896	50/18722	0.914167419676952	0.939857752141151	SH2B3	1
GO:0030178	negative regulation of Wnt signaling pathway	5/896	170/18722	0.914197340527222	0.939857752141151	EGR1/RNF213/PFDN5/STK4/CYLD	5
GO:0022904	respiratory electron transport chain	3/896	114/18722	0.914794736820178	0.940100262043419	SCO2/BID/PLEC	3
GO:0046660	female sex differentiation	3/896	114/18722	0.914794736820178	0.940100262043419	ARRB2/RETN/CEBPB	3
GO:0031023	microtubule organizing center organization	4/896	143/18722	0.91580284758138	0.94095033786463	NIN/PPP1R12A/CHMP1B/NUP62	4
GO:0042471	ear morphogenesis	3/896	115/18722	0.917695829048278	0.942709067130179	MAFB/MAPK1/NIPBL	3
GO:0009584	detection of visible light	1/896	51/18722	0.918286206736155	0.942756920891185	GNAQ	1
GO:0009948	anterior/posterior axis specification	1/896	51/18722	0.918286206736155	0.942756920891185	ETS2	1
GO:0065002	intracellular protein transmembrane transport	1/896	51/18722	0.918286206736155	0.942756920891185	TOMM7	1
GO:0009798	axis specification	2/896	86/18722	0.922037741523246	0.946222432778337	NOTCH2/ETS2	2
GO:0034204	lipid translocation	1/896	52/18722	0.922207558499018	0.946222432778337	PLSCR1	1
GO:0043090	amino acid import	1/896	52/18722	0.922207558499018	0.946222432778337	RGS2	1
GO:1901606	alpha-amino acid catabolic process	2/896	87/18722	0.925081194615201	0.948983687020446	KYNU/GLUL	2
GO:0032784	regulation of DNA-templated transcription, elongation	1/896	53/18722	0.925940929017758	0.94949108277235	HNRNPU	1
GO:0050819	negative regulation of coagulation	1/896	53/18722	0.925940929017758	0.94949108277235	SH2B3	1
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	1/896	54/18722	0.929495320126017	0.952572445315353	HMOX1	1
GO:0010524	positive regulation of calcium ion transport into cytosol	1/896	54/18722	0.929495320126017	0.952572445315353	CALM2	1
GO:0072348	sulfur compound transport	1/896	54/18722	0.929495320126017	0.952572445315353	MGST1	1
GO:0007389	pattern specification process	15/896	436/18722	0.931735142946375	0.954679763290799	BTG2/MAFB/MEF2C/NOTCH2/LFNG/ITGAM/HHEX/PRKACA/HIF1A/ATP6AP2/TGFBR2/ABI1/HIPK1/ETS2/EP300	15
GO:0035725	sodium ion transmembrane transport	5/896	178/18722	0.932130279498688	0.954848994018368	FXYD5/SLC8A1/GLRX/CHP1/WNK1	5
GO:0048562	embryonic organ morphogenesis	9/896	285/18722	0.932373908437875	0.954848994018368	MAFB/MEF2C/NOTCH2/HIF1A/MAPK1/NIPBL/TGFBR2/HIPK1/SP3	9
GO:0006360	transcription by RNA polymerase I	1/896	55/18722	0.932879303046903	0.954848994018368	FLNA	1
GO:0006414	translational elongation	1/896	55/18722	0.932879303046903	0.954848994018368	EEF2	1
GO:0002455	humoral immune response mediated by circulating immunoglobulin	3/896	121/18722	0.933287293968997	0.954848994018368	PTPRC/PTPN6/TNF	3
GO:0042752	regulation of circadian rhythm	3/896	121/18722	0.933287293968997	0.954848994018368	GNAQ/KLF10/CREB1	3
GO:0060271	cilium assembly	11/896	337/18722	0.933399649892053	0.954848994018368	FLNA/SNX10/ACTR2/RILPL2/CCDC88A/ACTR3/ATP6V0D1/ATG3/SCLT1/CYLD/CEP350	11
GO:0035278	miRNA mediated inhibition of translation	2/896	90/18722	0.933552611917593	0.954848994018368	ZFP36/STAT3	2
GO:0040033	negative regulation of translation, ncRNA-mediated	2/896	90/18722	0.933552611917593	0.954848994018368	ZFP36/STAT3	2
GO:0072329	monocarboxylic acid catabolic process	3/896	122/18722	0.935604699935759	0.956396553073909	PGD/DECR1/IRS2	3
GO:0051321	meiotic cell cycle	8/896	261/18722	0.93583774010633	0.956396553073909	DUSP1/ACTR2/ACTR3/PRKAR1A/SUN2/ATM/STAG2/MYH9	8
GO:0042733	embryonic digit morphogenesis	1/896	56/18722	0.936101038969653	0.956396553073909	CREBBP	1
GO:0006354	DNA-templated transcription, elongation	2/896	91/18722	0.936168977446504	0.956396553073909	ARID1A/HNRNPU	2
GO:0045974	regulation of translation, ncRNA-mediated	2/896	91/18722	0.936168977446504	0.956396553073909	ZFP36/STAT3	2
GO:0098661	inorganic anion transmembrane transport	2/896	91/18722	0.936168977446504	0.956396553073909	PTAFR/PRNP	2
GO:0046395	carboxylic acid catabolic process	7/896	236/18722	0.938421870870902	0.958331238227968	KYNU/GLUL/NAGK/PGD/HNMT/DECR1/IRS2	7
GO:0006497	protein lipidation	2/896	92/18722	0.938687473656616	0.958331238227968	GLUL/ZDHHC20	2
GO:0010257	NADH dehydrogenase complex assembly	1/896	57/18722	0.939168298644098	0.958331238227968	OXA1L	1
GO:0032981	mitochondrial respiratory chain complex I assembly	1/896	57/18722	0.939168298644098	0.958331238227968	OXA1L	1
GO:0051205	protein insertion into membrane	1/896	57/18722	0.939168298644098	0.958331238227968	OXA1L	1
GO:0060042	retina morphogenesis in camera-type eye	1/896	57/18722	0.939168298644098	0.958331238227968	HIPK1	1
GO:0033108	mitochondrial respiratory chain complex assembly	2/896	93/18722	0.941111462194538	0.959749159779174	SCO2/OXA1L	2
GO:0045132	meiotic chromosome segregation	2/896	93/18722	0.941111462194538	0.959749159779174	ACTR2/ACTR3	2
GO:0060993	kidney morphogenesis	2/896	93/18722	0.941111462194538	0.959749159779174	LRRK2/STAT1	2
GO:0007131	reciprocal meiotic recombination	1/896	58/18722	0.942088481039752	0.959834926945843	ATM	1
GO:0035904	aorta development	1/896	58/18722	0.942088481039752	0.959834926945843	CNTRL	1
GO:0097035	regulation of membrane lipid distribution	1/896	58/18722	0.942088481039752	0.959834926945843	PLSCR1	1
GO:0140527	reciprocal homologous recombination	1/896	58/18722	0.942088481039752	0.959834926945843	ATM	1
GO:2000027	regulation of animal organ morphogenesis	3/896	125/18722	0.94211830456807	0.959834926945843	TNF/RHOA/CDC42	3
GO:0048704	embryonic skeletal system morphogenesis	2/896	94/18722	0.943444207548884	0.960997517325058	NIPBL/TGFBR2	2
GO:0016054	organic acid catabolic process	7/896	240/18722	0.944688809144684	0.9620716034504	KYNU/GLUL/NAGK/PGD/HNMT/DECR1/IRS2	7
GO:0051055	negative regulation of lipid biosynthetic process	1/896	59/18722	0.94486863111414	0.9620716034504	NFKB1	1
GO:0007030	Golgi organization	4/896	157/18722	0.946254283744049	0.963293898953376	VMP1/LRRK2/CDC42/MAPK1	4
GO:0006289	nucleotide-excision repair	1/896	60/18722	0.947515456732837	0.964200330750828	POLK	1
GO:0035825	homologous recombination	1/896	60/18722	0.947515456732837	0.964200330750828	ATM	1
GO:0042158	lipoprotein biosynthetic process	2/896	96/18722	0.947848550472572	0.964350608569611	GLUL/ZDHHC20	2
GO:0006900	vesicle budding from membrane	1/896	61/18722	0.950035344781673	0.966008568564903	PICALM	1
GO:0042255	ribosome assembly	1/896	61/18722	0.950035344781673	0.966008568564903	DDX3X	1
GO:1905515	non-motile cilium assembly	1/896	61/18722	0.950035344781673	0.966008568564903	CEP350	1
GO:0042476	odontogenesis	3/896	130/18722	0.951632747467095	0.967443690300305	SNX10/TCIRG1/RHOA	3
GO:0003333	amino acid transmembrane transport	2/896	98/18722	0.951924737219798	0.967551408692626	RGS2/SLC7A7	2
GO:0048663	neuron fate commitment	1/896	62/18722	0.952434376509641	0.967880264209974	CDC42	1
GO:0071805	potassium ion transmembrane transport	6/896	219/18722	0.953839887264418	0.968937105114621	FLNA/KCNE3/PTEN/CAB39/PRNP/WNK1	6
GO:0015837	amine transport	2/896	99/18722	0.953846948315104	0.968937105114621	RGS2/AQP9	2
GO:0048705	skeletal system morphogenesis	6/896	220/18722	0.955161797565341	0.970083286299031	FGR/MEF2C/ZFAND5/NIPBL/TGFBR2/FOXN3	6
GO:0006664	glycolipid metabolic process	2/896	100/18722	0.955695556175672	0.970246454747154	ST8SIA4/NAGA	2
GO:0009062	fatty acid catabolic process	2/896	100/18722	0.955695556175672	0.970246454747154	DECR1/IRS2	2
GO:0030858	positive regulation of epithelial cell differentiation	1/896	64/18722	0.956892754778842	0.971222908135133	BTG1	1
GO:0007018	microtubule-based movement	12/896	382/18722	0.95703084102914	0.971222908135133	ACTR2/BLOC1S1/ACTR3/AGTPBP1/CDC42/HIF1A/SUN2/BICD2/HNRNPU/DYNLT1/DYNC1LI1/BLOC1S6	12
GO:0051963	regulation of synapse assembly	2/896	101/18722	0.957473192931596	0.97148226227804	MEF2C/TLR2	2
GO:0007286	spermatid development	4/896	165/18722	0.958754225809293	0.972592301235447	PRKACA/QKI/CELF1/CIB1	4
GO:0006487	protein N-linked glycosylation	1/896	65/18722	0.958962863671444	0.972614246091103	MGAT1	1
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	4/896	167/18722	0.961428654630934	0.97473497714142	PECAM1/CD84/PLXNB2/EMB	4
GO:0009451	RNA modification	4/896	167/18722	0.961428654630934	0.97473497714142	APOBEC3A/NUDT16/TRMT1/ADAR	4
GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	1/896	67/18722	0.962809922949196	0.975754951141615	CCR1	1
GO:0009583	detection of light stimulus	1/896	67/18722	0.962809922949196	0.975754951141615	GNAQ	1
GO:0009247	glycolipid biosynthetic process	1/896	68/18722	0.964596163047697	0.977184387224595	ST8SIA4	1
GO:1901607	alpha-amino acid biosynthetic process	1/896	68/18722	0.964596163047697	0.977184387224595	GLUL	1
GO:0048515	spermatid differentiation	4/896	172/18722	0.967427202068168	0.979212073255592	PRKACA/QKI/CELF1/CIB1	4
GO:0048736	appendage development	4/896	172/18722	0.967427202068168	0.979212073255592	MBNL1/NOTCH2/NIPBL/CREBBP	4
GO:0060173	limb development	4/896	172/18722	0.967427202068168	0.979212073255592	MBNL1/NOTCH2/NIPBL/CREBBP	4
GO:1903046	meiotic cell cycle process	5/896	202/18722	0.967557878287707	0.979212073255592	ACTR2/ACTR3/PRKAR1A/ATM/MYH9	5
GO:0006119	oxidative phosphorylation	3/896	141/18722	0.967662323851079	0.979212073255592	BID/RHOA/CHCHD10	3
GO:0044782	cilium organization	11/896	368/18722	0.967761303918846	0.979212073255592	FLNA/SNX10/ACTR2/RILPL2/CCDC88A/ACTR3/ATP6V0D1/ATG3/SCLT1/CYLD/CEP350	11
GO:0003407	neural retina development	1/896	70/18722	0.967915644800423	0.979212073255592	HIPK1	1
GO:0006865	amino acid transport	3/896	143/18722	0.969975883876993	0.981105517705998	RGS2/SLC11A1/SLC7A7	3
GO:0035924	cellular response to vascular endothelial growth factor stimulus	1/896	73/18722	0.972321090275976	0.982904176972858	NR4A1	1
GO:0051937	catecholamine transport	1/896	73/18722	0.972321090275976	0.982904176972858	ACTB	1
GO:0072088	nephron epithelium morphogenesis	1/896	73/18722	0.972321090275976	0.982904176972858	STAT1	1
GO:0001578	microtubule bundle formation	2/896	113/18722	0.974119619156752	0.984530924841482	CHP1/ZNF207	2
GO:0061333	renal tubule morphogenesis	1/896	75/18722	0.974916957614036	0.985145346133786	MEF2C	1
GO:0072028	nephron morphogenesis	1/896	76/18722	0.976122213471698	0.986171645739374	STAT1	1
GO:0042254	ribosome biogenesis	8/896	299/18722	0.976748105201676	0.986612331550576	GLUL/NUDT16/PTEN/XRN2/DDX21/DDX3X/WDR74/RSL24D1	8
GO:0031016	pancreas development	1/896	77/18722	0.977269617565303	0.986947433195561	IL6R	1
GO:0098656	anion transmembrane transport	6/896	245/18722	0.97884851485403	0.988350053534423	RGS2/PTAFR/SLC16A3/MPC1/PRNP/EMB	6
GO:0140013	meiotic nuclear division	4/896	185/18722	0.979199558846846	0.988512598129356	ACTR2/ACTR3/PRKAR1A/ATM	4
GO:0009100	glycoprotein metabolic process	11/896	387/18722	0.979943374282267	0.989071509730656	CST3/HBEGF/SULF2/SERP1/CSGALNACT2/CHP1/ST8SIA4/MGAT1/HIF1A/TET2/DSE	11
GO:0001942	hair follicle development	1/896	81/18722	0.981334239311856	0.990283154571394	TNF	1
GO:0001510	RNA methylation	1/896	83/18722	0.983085541006549	0.9918579823036	TRMT1	1
GO:0009953	dorsal/ventral pattern formation	1/896	84/18722	0.983898640167348	0.992100974701507	PRKACA	1
GO:0022404	molting cycle process	1/896	84/18722	0.983898640167348	0.992100974701507	TNF	1
GO:0022405	hair cycle process	1/896	84/18722	0.983898640167348	0.992100974701507	TNF	1
GO:0006520	cellular amino acid metabolic process	7/896	284/18722	0.984312786871403	0.99211210429149	DPYD/SLC7A7/ALDH1A1/KYNU/GLUL/HNMT/CARS2	7
GO:0030433	ubiquitin-dependent ERAD pathway	1/896	85/18722	0.984672694165097	0.99211210429149	HERPUD1	1
GO:0060021	roof of mouth development	1/896	85/18722	0.984672694165097	0.99211210429149	TGFBR2	1
GO:0098773	skin epidermis development	1/896	85/18722	0.984672694165097	0.99211210429149	TNF	1
GO:0006486	protein glycosylation	5/896	226/18722	0.985173138967024	0.992231893061095	SERP1/CHP1/ST8SIA4/MGAT1/TET2	5
GO:0043413	macromolecule glycosylation	5/896	226/18722	0.985173138967024	0.992231893061095	SERP1/CHP1/ST8SIA4/MGAT1/TET2	5
GO:0006493	protein O-linked glycosylation	1/896	86/18722	0.985409575960884	0.992277871166032	TET2	1
GO:0009101	glycoprotein biosynthetic process	8/896	317/18722	0.98610682368678	0.992787764226664	HBEGF/SERP1/CSGALNACT2/CHP1/ST8SIA4/MGAT1/TET2/DSE	8
GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	2/896	130/18722	0.987376746667611	0.993873903506531	LRRK2/SORL1	2
GO:0006400	tRNA modification	1/896	90/18722	0.988019787933992	0.993944084534757	TRMT1	1
GO:0042475	odontogenesis of dentin-containing tooth	1/896	90/18722	0.988019787933992	0.993944084534757	TCIRG1	1
GO:0048477	oogenesis	1/896	90/18722	0.988019787933992	0.993944084534757	PTK2B	1
GO:0051952	regulation of amine transport	1/896	91/18722	0.98859590805052	0.994331331999759	RGS2	1
GO:0016072	rRNA metabolic process	5/896	236/18722	0.989422098275313	0.994969901997275	NUDT16/XRN2/DDX21/XRN1/WDR74	5
GO:0042773	ATP synthesis coupled electron transport	1/896	95/18722	0.990636596235579	0.995752195495353	BID	1
GO:0042775	mitochondrial ATP synthesis coupled electron transport	1/896	95/18722	0.990636596235579	0.995752195495353	BID	1
GO:0070085	glycosylation	5/896	240/18722	0.99077439178782	0.995752195495353	SERP1/CHP1/ST8SIA4/MGAT1/TET2	5
GO:0042472	inner ear morphogenesis	1/896	96/18722	0.991086996717295	0.995873931593248	MAFB	1
GO:0043583	ear development	4/896	213/18722	0.992384202576125	0.996868593325276	MAFB/ADAM10/MAPK1/NIPBL	4
GO:0006399	tRNA metabolic process	3/896	179/18722	0.992460214619935	0.996868593325276	TRMT1/CARS2/DICER1	3
GO:0060840	artery development	1/896	100/18722	0.992682317816823	0.996899157166498	CNTRL	1
GO:0007218	neuropeptide signaling pathway	1/896	106/18722	0.994556698460947	0.998573603532354	SORL1	1
GO:0036503	ERAD pathway	1/896	107/18722	0.994818688049419	0.998573603532354	HERPUD1	1
GO:0140053	mitochondrial gene expression	1/896	108/18722	0.995068081307959	0.998573603532354	CHCHD10	1
GO:0006364	rRNA processing	4/896	225/18722	0.995117667200191	0.998573603532354	NUDT16/XRN2/DDX21/WDR74	4
GO:0022412	cellular process involved in reproduction in multicellular organism	9/896	384/18722	0.995481447261073	0.998745950463897	ARRB2/RETN/KDM1B/PTK2B/PRKACA/PRKAR1A/QKI/CELF1/CIB1	9
GO:1901605	alpha-amino acid metabolic process	3/896	195/18722	0.996013760171055	0.999087283828285	SLC7A7/KYNU/GLUL	3
GO:0034470	ncRNA processing	9/896	395/18722	0.996765957356954	0.999471733820146	NUDT16/TRMT1/STAT3/ADAR/DICER1/XRN2/DDX21/DDX3X/WDR74	9
GO:0065004	protein-DNA complex assembly	3/896	201/18722	0.99687079539495	0.999471733820146	RB1/PIAS1/CREB1	3
GO:0034660	ncRNA metabolic process	12/896	485/18722	0.996973534908463	0.999471733820146	NUDT16/TRMT1/STAT3/CARS2/ADAR/DICER1/XRN2/DDX21/DDX3X/XRN1/WDR74/NFKB1	12
GO:0071824	protein-DNA complex subunit organization	4/896	241/18722	0.997331497794121	0.99963791097075	RB1/PIAS1/ARID1A/CREB1	4
GO:0007281	germ cell development	5/896	278/18722	0.99759158162572	0.999653022949102	PTK2B/PRKACA/QKI/CELF1/CIB1	5
GO:0008033	tRNA processing	1/896	127/18722	0.9980691933801	0.999653022949102	TRMT1	1
GO:0007601	visual perception	3/896	215/18722	0.998231601371001	0.999653022949102	PPT1/TGFBI/DRAM2	3
GO:0007127	meiosis I	1/896	129/18722	0.998250787026024	0.999653022949102	ATM	1
GO:0071103	DNA conformation change	5/896	290/18722	0.998446906014726	0.999653022949102	HHEX/SETX/CHD1/CHD9/DDX3X	5
GO:0050953	sensory perception of light stimulus	3/896	219/18722	0.998499798927242	0.999653022949102	PPT1/TGFBI/DRAM2	3
GO:0061982	meiosis I cell cycle process	1/896	135/18722	0.998699453044936	0.999660480232239	ATM	1
GO:0048839	inner ear development	2/896	188/18722	0.999003407390062	0.999772315150224	MAFB/ADAM10	2
GO:0007338	single fertilization	1/896	153/18722	0.999465779727844	0.999914447095775	MYH9	1
GO:0034728	nucleosome organization	1/896	167/18722	0.999732750399607	0.999914447095775	ARID1A	1
GO:0006333	chromatin assembly or disassembly	1/896	177/18722	0.999837102250972	0.999914447095775	ARID1A	1
GO:0009566	fertilization	1/896	190/18722	0.999914447095775	0.999914447095775	MYH9	1