ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0002181 cytoplasmic translation 87/719 148/18722 1.10914607807117e-84 4.270212400574e-81 RPLP0/RPL35/RPS10/RPL8/RPSA/RPL14/RPL7A/RPL23A/RPS5/RPS3/RPS3A/RPS2/RPL3/RPS16/RPL15/RPS6/RPS12/RPL18A/RPS19/RPL27A/RPL6/RPL10A/RPS8/RPL26/RPL29/RPS13/RPS23/RPL13A/RPL32/RPS15/RPL22/RPS4X/RPL24/RPS25/RPL13/RPLP1/RPL11/RPL21/RPS14/RPS18/RPS7/RPL18/RPS27A/RPS15A/RPL9/RPL19/RPL12/RPS24/RPL41/RPL27/RPL28/RPL37/RPL31/RPL5/UBA52/RPS20/RPL10/RPL7/RPLP2/RPS26/RPL35A/RPL30/RPL36A/RPL36/RPS17/RPL34/PKM/RPL37A/RPS28/RPL23/TMA7/RPL4/RPS29/RPS9/RPS11/EIF3F/EIF2S2/RPL17/EIF3K/EIF3H/EIF3I/EIF3M/EIF3L/RWDD1/RPL26L1/RPL22L1/MCTS1 87 GO:0022613 ribonucleoprotein complex biogenesis 84/719 463/18722 1.54504136953366e-33 2.97420463635229e-30 RAN/SNRPD1/SNRPG/SNRPE/RPLP0/NPM1/RPL35/RPSA/RPL14/RPL7A/RPL23A/RPS5/RPL3/RPS16/RPS6/RPS19/RPL6/RPL10A/RPS8/RPL26/RPL13A/RPS15/RPL24/RPS25/RPL11/RPS14/RPS7/RPS24/RPL27/SNRPF/RPL5/SNRPD2/RPL10/RPL7/LSM4/RPL35A/PA2G4/SNRPB/PTGES3/RPS17/SNRPD3/TRMT112/LSM2/RPS28/EIF3F/EIF2S2/SNRPC/NHP2/SNU13/HSP90AB1/PSIP1/EXOSC8/C1QBP/MRPS7/HSP90AA1/POP7/EIF3K/EIF3H/EIF6/PIH1D1/LSM6/EIF3I/EIF3M/MPHOSPH6/MRPL20/RPP30/SRSF9/EBNA1BP2/MRPL22/METTL5/FBL/EIF3L/TXNL4A/NOP10/TAF9/BRIX1/NOP56/RUVBL1/IMP3/PIN4/RPL26L1/MRTO4/MCTS1/SF3A3 84 GO:0042773 ATP synthesis coupled electron transport 38/719 95/18722 3.82331047759341e-29 3.67993633468366e-26 CDK1/CHCHD2/UQCRH/UQCRQ/CCNB1/COX5A/UQCR10/COX7C/COX8A/PARK7/NDUFS5/NDUFA4/NDUFA6/NDUFS6/COX4I1/NDUFB2/COX5B/COX7A2/COX6C/NDUFB4/NDUFB10/NDUFV2/NDUFAB1/NDUFS8/NDUFB6/NDUFB3/NDUFA12/NDUFB1/NDUFB7/CYCS/NDUFA2/NDUFA10/CYC1/NDUFV1/NDUFB8/ISCU/COA6/NDUFS3 38 GO:0042775 mitochondrial ATP synthesis coupled electron transport 38/719 95/18722 3.82331047759341e-29 3.67993633468366e-26 CDK1/CHCHD2/UQCRH/UQCRQ/CCNB1/COX5A/UQCR10/COX7C/COX8A/PARK7/NDUFS5/NDUFA4/NDUFA6/NDUFS6/COX4I1/NDUFB2/COX5B/COX7A2/COX6C/NDUFB4/NDUFB10/NDUFV2/NDUFAB1/NDUFS8/NDUFB6/NDUFB3/NDUFA12/NDUFB1/NDUFB7/CYCS/NDUFA2/NDUFA10/CYC1/NDUFV1/NDUFB8/ISCU/COA6/NDUFS3 38 GO:0022900 electron transport chain 49/719 175/18722 7.2972507262674e-29 5.6188830592259e-26 CDK1/CHCHD2/UQCRH/UQCRQ/CCNB1/COX5A/UQCR10/COX7C/COX8A/PARK7/NDUFS5/NDUFA4/CYB5A/ETFB/NDUFA6/AKR7A2/NDUFS6/COX4I1/NDUFB2/COX5B/COX7B/COX6B1/COX7A2/COX6C/NDUFB4/NDUFB10/NDUFV2/NDUFAB1/NDUFS8/NDUFB6/NDUFB3/AKR1B1/ADH5/NDUFA12/NDUFB1/NDUFA13/UQCRFS1/NDUFB7/CYCS/ETFA/NDUFA2/NDUFA10/CYC1/NDUFV1/NDUFB8/ISCU/COA6/NDUFS3/CYB5B 49 GO:0009060 aerobic respiration 50/719 189/18722 3.68563073794288e-28 2.36494639018001e-25 CDK1/CHCHD2/UQCRH/UQCRQ/CCNB1/COX5A/UQCR10/COX7C/COX8A/PARK7/NDUFS5/NDUFA4/NDUFA6/UQCC2/NDUFS6/COX4I1/NDUFB2/COX5B/IDH2/COX7B/ARL2/MDH1/COX6B1/MDH2/COX7A2/COX6C/NDUFB4/NDUFB10/NDUFV2/NDUFAB1/NDUFS8/NDUFB6/STOML2/NDUFB3/NDUFA12/NDUFB1/NDUFB7/CYCS/PPIF/FH/NDUFA2/NDUFA10/CYC1/NDUFV1/NDUFB8/BNIP3/ISCU/SUCLG1/COA6/NDUFS3 50 GO:0006119 oxidative phosphorylation 43/719 141/18722 3.80595374259942e-27 2.09327455842968e-24 CDK1/CHCHD2/UQCRH/UQCRQ/CCNB1/COX5A/UQCR10/COX7C/COX8A/PARK7/NDUFS5/NDUFA4/NDUFA6/UQCC2/NDUFS6/COX4I1/NDUFB2/COX5B/COX7B/COX6B1/COX7A2/COX6C/NDUFB4/NDUFB10/NDUFV2/NDUFAB1/NDUFS8/NDUFB6/STOML2/NDUFB3/NDUFA12/NDUFB1/NDUFB7/CYCS/PPIF/NDUFA2/NDUFA10/CYC1/NDUFV1/NDUFB8/ISCU/COA6/NDUFS3 43 GO:0022904 respiratory electron transport chain 39/719 114/18722 7.50254998055543e-27 3.6106021781423e-24 CDK1/CHCHD2/UQCRH/UQCRQ/CCNB1/COX5A/UQCR10/COX7C/COX8A/PARK7/NDUFS5/NDUFA4/NDUFA6/NDUFS6/COX4I1/NDUFB2/COX5B/COX7A2/COX6C/NDUFB4/NDUFB10/NDUFV2/NDUFAB1/NDUFS8/NDUFB6/NDUFB3/NDUFA12/NDUFB1/UQCRFS1/NDUFB7/CYCS/NDUFA2/NDUFA10/CYC1/NDUFV1/NDUFB8/ISCU/COA6/NDUFS3 39 GO:0045333 cellular respiration 53/719 230/18722 1.30513737550725e-26 5.58308766189212e-24 CDK1/CHCHD2/UQCRH/UQCRQ/CCNB1/COX5A/UQCR10/COX7C/COX8A/PARK7/NDUFS5/NDUFA4/PRELID1/NDUFA6/UQCC2/NDUFS6/COX4I1/NDUFB2/COX5B/IDH2/COX7B/ARL2/MDH1/COX6B1/MDH2/COX7A2/COX6C/NDUFB4/NDUFB10/NDUFV2/NDUFAB1/NDUFS8/NDUFB6/STOML2/NDUFB3/NDUFA12/NDUFB1/UQCRFS1/NDUFB7/CYCS/PPIF/CISD1/FH/NDUFA2/NDUFA10/CYC1/NDUFV1/NDUFB8/BNIP3/ISCU/SUCLG1/COA6/NDUFS3 53 GO:0006091 generation of precursor metabolites and energy 77/719 490/18722 1.6249519739079e-26 6.2560650995454e-24 HMGB1/CDK1/GAPDH/LDHA/ENO1/TPI1/ALDOA/CHCHD2/UQCRH/UQCRQ/CCNB1/PTGES3/COX5A/UQCR10/COX7C/COX8A/PARK7/PKM/NDUFS5/NDUFA4/PGAM1/CYB5A/PRELID1/ETFB/NDUFA6/UQCC2/AKR7A2/NDUFS6/COX4I1/NDUFB2/COX5B/IDH2/COX7B/ARL2/MDH1/PPP1CA/COX17/COX6B1/MDH2/PHLDA2/COX7A2/COX6C/NDUFB4/NDUFB10/NDUFV2/NDUFAB1/NDUFS8/NDUFB6/STOML2/NDUFB3/AKR1B1/ADH5/NDUFA12/EIF6/NDUFB1/NDUFA13/UQCRFS1/NDUFB7/TALDO1/CYCS/UGP2/PPIF/ETFA/CISD1/PHB2/FH/NDUFA2/NDUFA10/CYC1/NDUFV1/NDUFB8/BNIP3/ISCU/SUCLG1/COA6/NDUFS3/CYB5B 77 GO:0046034 ATP metabolic process 56/719 277/18722 5.17627807423776e-25 1.81169732598321e-22 CDK1/GAPDH/LDHA/ENO1/TPI1/ALDOA/CHCHD2/UQCRH/UQCRQ/CCNB1/COX5A/UQCR10/COX7C/COX8A/PARK7/PKM/NDUFS5/NDUFA4/PGAM1/NDUFA6/UQCC2/NDUFS6/COX4I1/NDUFB2/COX5B/COX7B/ARL2/COX6B1/COX7A2/COX6C/NDUFB4/NDUFB10/NDUFV2/NDUFAB1/NDUFS8/NDUFB6/STOML2/NDUFB3/NDUFA12/OLA1/EIF6/NDUFB1/NDUFB7/CYCS/PPIF/NUDT5/PARP1/NDUFA2/AK2/NDUFA10/CYC1/NDUFV1/NDUFB8/ISCU/COA6/NDUFS3 56 GO:0019646 aerobic electron transport chain 33/719 87/18722 1.39147069570972e-24 4.46430181540202e-22 UQCRH/UQCRQ/COX5A/UQCR10/COX7C/COX8A/PARK7/NDUFS5/NDUFA4/NDUFA6/NDUFS6/COX4I1/NDUFB2/COX5B/COX7A2/COX6C/NDUFB4/NDUFB10/NDUFV2/NDUFAB1/NDUFS8/NDUFB6/NDUFB3/NDUFB1/NDUFB7/CYCS/NDUFA2/NDUFA10/CYC1/NDUFV1/NDUFB8/ISCU/NDUFS3 33 GO:0022618 ribonucleoprotein complex assembly 49/719 220/18722 5.60869235183532e-24 1.66103581188969e-21 SNRPD1/SNRPG/SNRPE/RPLP0/RPSA/RPL23A/RPS5/RPL3/RPS19/RPL6/RPL13A/RPS15/RPL24/RPL11/RPS14/SNRPF/RPL5/SNRPD2/RPL10/LSM4/SNRPB/PTGES3/SNRPD3/LSM2/RPS28/EIF3F/EIF2S2/SNRPC/SNU13/HSP90AB1/PSIP1/MRPS7/HSP90AA1/EIF3K/EIF3H/EIF6/PIH1D1/EIF3I/EIF3M/MRPL20/SRSF9/EIF3L/TXNL4A/TAF9/BRIX1/RUVBL1/MRTO4/MCTS1/SF3A3 49 GO:0015980 energy derivation by oxidation of organic compounds 58/719 318/18722 1.75857112954939e-23 4.83607060626082e-21 HMGB1/CDK1/CHCHD2/UQCRH/UQCRQ/CCNB1/PTGES3/COX5A/UQCR10/COX7C/COX8A/PARK7/NDUFS5/NDUFA4/PRELID1/NDUFA6/UQCC2/NDUFS6/COX4I1/NDUFB2/COX5B/IDH2/COX7B/ARL2/MDH1/PPP1CA/COX6B1/MDH2/PHLDA2/COX7A2/COX6C/NDUFB4/NDUFB10/NDUFV2/NDUFAB1/NDUFS8/NDUFB6/STOML2/NDUFB3/NDUFA12/NDUFB1/UQCRFS1/NDUFB7/CYCS/UGP2/PPIF/CISD1/FH/NDUFA2/NDUFA10/CYC1/NDUFV1/NDUFB8/BNIP3/ISCU/SUCLG1/COA6/NDUFS3 58 GO:0071826 ribonucleoprotein complex subunit organization 49/719 227/18722 2.45410644953361e-23 6.29887322046961e-21 SNRPD1/SNRPG/SNRPE/RPLP0/RPSA/RPL23A/RPS5/RPL3/RPS19/RPL6/RPL13A/RPS15/RPL24/RPL11/RPS14/SNRPF/RPL5/SNRPD2/RPL10/LSM4/SNRPB/PTGES3/SNRPD3/LSM2/RPS28/EIF3F/EIF2S2/SNRPC/SNU13/HSP90AB1/PSIP1/MRPS7/HSP90AA1/EIF3K/EIF3H/EIF6/PIH1D1/EIF3I/EIF3M/MRPL20/SRSF9/EIF3L/TXNL4A/TAF9/BRIX1/RUVBL1/MRTO4/MCTS1/SF3A3 49 GO:0042254 ribosome biogenesis 56/719 299/18722 2.72027335076033e-23 6.54565775026705e-21 RAN/RPLP0/NPM1/RPL35/RPSA/RPL14/RPL7A/RPL23A/RPS5/RPL3/RPS16/RPS6/RPS19/RPL6/RPL10A/RPS8/RPL26/RPS15/RPL24/RPS25/RPL11/RPS14/RPS7/RPS24/RPL27/RPL5/RPL10/RPL7/RPL35A/PA2G4/RPS17/TRMT112/RPS28/NHP2/SNU13/EXOSC8/C1QBP/MRPS7/POP7/EIF6/PIH1D1/LSM6/MPHOSPH6/MRPL20/RPP30/EBNA1BP2/MRPL22/METTL5/FBL/NOP10/BRIX1/NOP56/IMP3/PIN4/RPL26L1/MRTO4 56 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 52/719 320/18722 7.57966674511377e-19 1.62120649826045e-16 SNRPD1/SNRPG/SNRPE/LSM3/NPM1/HNRNPA1/SNRPF/SNRPD2/LSM4/SNRPB/SNRPD3/LSM2/LSM5/PRDX6/HNRNPA3/SRSF3/LSM7/SNRPC/SNU13/HNRNPA2B1/HNRNPF/SF3B6/PSIP1/SAP18/C1QBP/SNRPA1/MAGOH/UBL5/ZCRB1/RBM8A/NCL/SF3B5/LSM6/SNRNP25/ALYREF/SRSF9/DDX39A/SNRNP40/PPIL1/PPIH/MAGOHB/TXNL4A/RBM17/RBM3/HNRNPR/RALY/CWC15/SNRPA/HNRNPM/LSM8/SF3A3/BUD31 52 GO:0000398 mRNA splicing, via spliceosome 52/719 320/18722 7.57966674511377e-19 1.62120649826045e-16 SNRPD1/SNRPG/SNRPE/LSM3/NPM1/HNRNPA1/SNRPF/SNRPD2/LSM4/SNRPB/SNRPD3/LSM2/LSM5/PRDX6/HNRNPA3/SRSF3/LSM7/SNRPC/SNU13/HNRNPA2B1/HNRNPF/SF3B6/PSIP1/SAP18/C1QBP/SNRPA1/MAGOH/UBL5/ZCRB1/RBM8A/NCL/SF3B5/LSM6/SNRNP25/ALYREF/SRSF9/DDX39A/SNRNP40/PPIL1/PPIH/MAGOHB/TXNL4A/RBM17/RBM3/HNRNPR/RALY/CWC15/SNRPA/HNRNPM/LSM8/SF3A3/BUD31 52 GO:0000375 RNA splicing, via transesterification reactions 52/719 324/18722 1.32584378276797e-18 2.68657819139826e-16 SNRPD1/SNRPG/SNRPE/LSM3/NPM1/HNRNPA1/SNRPF/SNRPD2/LSM4/SNRPB/SNRPD3/LSM2/LSM5/PRDX6/HNRNPA3/SRSF3/LSM7/SNRPC/SNU13/HNRNPA2B1/HNRNPF/SF3B6/PSIP1/SAP18/C1QBP/SNRPA1/MAGOH/UBL5/ZCRB1/RBM8A/NCL/SF3B5/LSM6/SNRNP25/ALYREF/SRSF9/DDX39A/SNRNP40/PPIL1/PPIH/MAGOHB/TXNL4A/RBM17/RBM3/HNRNPR/RALY/CWC15/SNRPA/HNRNPM/LSM8/SF3A3/BUD31 52 GO:0008380 RNA splicing 60/719 434/18722 4.86954477298352e-18 9.37387368799327e-16 SNRPD1/SNRPG/SNRPE/LSM3/NPM1/HNRNPA1/RPS13/SNRPF/SNRPD2/RPS26/LSM4/SNRPB/YBX1/SNRPD3/LSM2/LSM5/PRDX6/HNRNPA3/SRSF3/LSM7/SNRPC/SNU13/HNRNPA2B1/HNRNPF/CTNNBL1/SF3B6/PSIP1/SAP18/C1QBP/SNRPA1/MAGOH/TSEN34/UBL5/ZCRB1/RBM8A/NCL/SF3B5/LSM6/SNRNP25/ALYREF/SRSF9/DDX39A/SNRNP40/THOC6/PPIL1/PPIH/MAGOHB/PRMT1/TXNL4A/RBM17/RBM3/HNRNPR/RALY/ARL6IP4/CWC15/SNRPA/HNRNPM/LSM8/SF3A3/BUD31 60 GO:0006260 DNA replication 45/719 260/18722 1.51437718944278e-17 2.7763581806451e-15 PCNA/DUT/CDK1/GMNN/RPA3/NASP/RRM2/GINS2/RAD51/HMGA1/CDT1/CCNA2/RFC2/FEN1/RNASEH2A/RRM1/CDC6/MCM7/CACYBP/RFC4/NUCKS1/SSBP1/S100A11/RFC3/CCNE1/ORC6/RMI2/MCM5/POLD2/RPA2/PTMS/NAP1L1/SET/RBBP7/MCM4/STOML2/MCM3/ALYREF/POLD3/HRAS/SUPT16H/ID3/POLE3/SMC3/RFC1 45 GO:0006120 mitochondrial electron transport, NADH to ubiquinone 21/719 51/18722 5.43114735805044e-17 9.50450787658827e-15 PARK7/NDUFS5/NDUFA4/NDUFA6/NDUFS6/NDUFB2/NDUFB4/NDUFB10/NDUFV2/NDUFAB1/NDUFS8/NDUFB6/NDUFB3/NDUFB1/NDUFB7/NDUFA2/NDUFA10/NDUFV1/NDUFB8/ISCU/NDUFS3 21 GO:0006364 rRNA processing 41/719 225/18722 6.47161871718732e-17 1.06032353832022e-14 RPL35/RPL14/RPL7A/RPS16/RPS6/RPS19/RPL10A/RPS8/RPL26/RPS15/RPS25/RPL11/RPS14/RPS7/RPS24/RPL27/RPL5/RPL7/RPL35A/PA2G4/RPS17/TRMT112/RPS28/NHP2/SNU13/EXOSC8/POP7/EIF6/PIH1D1/LSM6/MPHOSPH6/RPP30/EBNA1BP2/METTL5/FBL/NOP10/BRIX1/NOP56/IMP3/PIN4/MRTO4 41 GO:0033108 mitochondrial respiratory chain complex assembly 27/719 93/18722 6.60980907004811e-17 1.06032353832022e-14 NDUFS5/COX20/NDUFA11/NDUFA6/UQCC2/NDUFB2/COX17/NDUFB11/NDUFB4/NDUFB10/NDUFAB1/NDUFS8/NDUFB6/NDUFB3/NDUFA12/COA4/NDUFB1/NDUFA13/UQCRFS1/NDUFB7/NDUFA2/COX14/COA3/NDUFA10/NDUFB8/TFAM/NDUFS3 27 GO:0042273 ribosomal large subunit biogenesis 24/719 72/18722 1.01394371747288e-16 1.56147332490824e-14 RPLP0/NPM1/RPL35/RPL14/RPL7A/RPL23A/RPL3/RPL6/RPL10A/RPL26/RPL24/RPL11/RPL5/RPL10/RPL7/RPL35A/NHP2/SNU13/EIF6/MRPL20/EBNA1BP2/BRIX1/RPL26L1/MRTO4 24 GO:0042255 ribosome assembly 22/719 61/18722 2.82637209090242e-16 4.18520482691319e-14 RPLP0/NPM1/RPSA/RPL23A/RPS5/RPL3/RPS19/RPL6/RPS15/RPL24/RPL11/RPS14/RPL5/RPL10/RPS28/C1QBP/MRPS7/EIF6/MRPL20/MRPL22/BRIX1/MRTO4 22 GO:0016072 rRNA metabolic process 41/719 236/18722 3.72763773440945e-16 5.31533528795421e-14 RPL35/RPL14/RPL7A/RPS16/RPS6/RPS19/RPL10A/RPS8/RPL26/RPS15/RPS25/RPL11/RPS14/RPS7/RPS24/RPL27/RPL5/RPL7/RPL35A/PA2G4/RPS17/TRMT112/RPS28/NHP2/SNU13/EXOSC8/POP7/EIF6/PIH1D1/LSM6/MPHOSPH6/RPP30/EBNA1BP2/METTL5/FBL/NOP10/BRIX1/NOP56/IMP3/PIN4/MRTO4 41 GO:0000723 telomere maintenance 30/719 131/18722 1.62503452962134e-15 2.23442247822934e-13 PCNA/RPA3/HNRNPA1/RAD51/AURKB/FEN1/PTGES3/CCNE1/CCT5/RAD51C/NHP2/HSP90AB1/HNRNPA2B1/RPA2/HNRNPD/TPRKB/HSP90AA1/XRCC6/CCT2/PKIB/CCT8/CCT3/APEX1/CCT7/PARP1/NOP10/CCT6A/CCT4/TCP1/RFC1 30 GO:0010257 NADH dehydrogenase complex assembly 19/719 57/18722 1.62221851940887e-13 2.08184709990805e-11 NDUFS5/NDUFA11/NDUFA6/NDUFB2/NDUFB11/NDUFB4/NDUFB10/NDUFAB1/NDUFS8/NDUFB6/NDUFB3/NDUFA12/NDUFB1/NDUFA13/NDUFB7/NDUFA2/NDUFA10/NDUFB8/NDUFS3 19 GO:0032981 mitochondrial respiratory chain complex I assembly 19/719 57/18722 1.62221851940887e-13 2.08184709990805e-11 NDUFS5/NDUFA11/NDUFA6/NDUFB2/NDUFB11/NDUFB4/NDUFB10/NDUFAB1/NDUFS8/NDUFB6/NDUFB3/NDUFA12/NDUFB1/NDUFA13/NDUFB7/NDUFA2/NDUFA10/NDUFB8/NDUFS3 19 GO:0007059 chromosome segregation 46/719 346/18722 1.82746442515951e-13 2.26959291511746e-11 UBE2C/NUSAP1/PTTG1/CENPW/RAN/CENPN/BIRC5/TOP2A/MAD2L1/PRC1/SLC25A5/SPC25/RPS3/AURKB/ANAPC11/CDT1/ZWINT/FEN1/CENPK/NUF2/CDC6/CDC20/CCNB1/SKA2/CCNE1/CENPH/BANF1/RAD51C/RMI2/TUBG1/BUB3/UBE2I/NUDC/ECT2/LCMT1/NUP37/PMF1/SMC2/MIS18A/SMC4/PHB2/NTMT1/PSMG2/ANAPC15/NAA10/SMC3 46 GO:1904666 regulation of ubiquitin protein ligase activity 13/719 23/18722 2.85073901212493e-13 3.33997902162338e-11 UBE2C/MAD2L1/RPS15/RPL11/RPS7/RPL37/RPL5/RPS20/UBE2S/CDC20/RPL23/SKP1/BAG2 13 GO:0006403 RNA localization 34/719 201/18722 2.86283916139147e-13 3.33997902162338e-11 RAN/NPM1/HNRNPA1/YBX1/SLBP/HNRNPA3/SRSF3/CCT5/NHP2/HNRNPA2B1/ENY2/MAGOH/CCT2/EIF5A/RBM8A/NUTF2/CCT8/PIH1D1/NUP37/ALYREF/CCT3/DDX39A/SSB/THOC6/FBL/MAGOHB/CCT7/NXT1/NOP10/CCT6A/MRPL18/CCT4/RUVBL1/TCP1 34 GO:1904874 positive regulation of telomerase RNA localization to Cajal body 11/719 15/18722 2.95027096986631e-13 3.34074800999568e-11 CCT5/NHP2/CCT2/CCT8/CCT3/CCT7/NOP10/CCT6A/CCT4/RUVBL1/TCP1 11 GO:0032200 telomere organization 30/719 159/18722 3.87015965467084e-13 4.25717562013792e-11 PCNA/RPA3/HNRNPA1/RAD51/AURKB/FEN1/PTGES3/CCNE1/CCT5/RAD51C/NHP2/HSP90AB1/HNRNPA2B1/RPA2/HNRNPD/TPRKB/HSP90AA1/XRCC6/CCT2/PKIB/CCT8/CCT3/APEX1/CCT7/PARP1/NOP10/CCT6A/CCT4/TCP1/RFC1 30 GO:0051438 regulation of ubiquitin-protein transferase activity 18/719 53/18722 4.90363627844458e-13 5.24416657555879e-11 UBE2C/MAD2L1/RPS2/RPS15/RPL11/RPS7/RPL37/RPL5/RPS20/UBE2S/CDC20/PARK7/RPL23/UBE2L3/UBE2N/SKP1/BAG2/PIN1 18 GO:0033044 regulation of chromosome organization 32/719 187/18722 1.04182483927744e-12 1.08406098141031e-10 UBE2C/PTTG1/TOP2A/MAD2L1/HNRNPA1/AURKB/ANAPC11/CDT1/ZWINT/FEN1/CDC6/CCNB1/SSBP1/CCT5/RMI2/HNRNPA2B1/HNRNPD/BUB3/CCT2/PKIB/CCT8/LCMT1/CCT3/CCT7/PARP1/DNMT1/CCT6A/PSMG2/CCT4/ANAPC15/NAA10/TCP1 32 GO:0071897 DNA biosynthetic process 31/719 180/18722 1.98193874528047e-12 2.00801688666574e-10 TYMS/PCNA/TK1/HNRNPA1/AURKB/RFC2/PTGES3/RFC4/RFC3/CCT5/NHP2/HSP90AB1/POLD2/HNRNPA2B1/HNRNPD/HSP90AA1/CCT2/PKIB/CCT8/CCT3/PHB/POLD3/CCT7/NOP10/CCT6A/CCT4/TFDP1/TCP1/POLE4/POLE3/RFC1 31 GO:0034470 ncRNA processing 47/719 395/18722 5.74820918385478e-12 5.67451419431818e-10 RPL35/RPL14/RPL7A/RPS16/RPS6/RPS19/RPL10A/RPS8/RPL26/RPS15/RPS25/RPL11/RPS14/RPS7/RPS24/RPL27/RPL5/RPL7/RPL35A/PA2G4/RPS17/TRMT112/RPS28/NHP2/SNU13/HNRNPA2B1/EXOSC8/TPRKB/POP7/POLR3K/TSEN34/EIF6/PIH1D1/LSM6/MPHOSPH6/RPP30/EBNA1BP2/SSB/METTL5/FBL/NOP10/BRIX1/HSD17B10/NOP56/IMP3/PIN4/MRTO4 47 GO:1904872 regulation of telomerase RNA localization to Cajal body 11/719 18/18722 6.18783099167654e-12 5.95578732948867e-10 CCT5/NHP2/CCT2/CCT8/CCT3/CCT7/NOP10/CCT6A/CCT4/RUVBL1/TCP1 11 GO:0090670 RNA localization to Cajal body 11/719 19/18722 1.41870918395701e-11 1.24137053596238e-09 CCT5/NHP2/CCT2/CCT8/CCT3/CCT7/NOP10/CCT6A/CCT4/RUVBL1/TCP1 11 GO:0090671 telomerase RNA localization to Cajal body 11/719 19/18722 1.41870918395701e-11 1.24137053596238e-09 CCT5/NHP2/CCT2/CCT8/CCT3/CCT7/NOP10/CCT6A/CCT4/RUVBL1/TCP1 11 GO:0090672 telomerase RNA localization 11/719 19/18722 1.41870918395701e-11 1.24137053596238e-09 CCT5/NHP2/CCT2/CCT8/CCT3/CCT7/NOP10/CCT6A/CCT4/RUVBL1/TCP1 11 GO:0090685 RNA localization to nucleus 11/719 19/18722 1.41870918395701e-11 1.24137053596238e-09 CCT5/NHP2/CCT2/CCT8/CCT3/CCT7/NOP10/CCT6A/CCT4/RUVBL1/TCP1 11 GO:0010833 telomere maintenance via telomere lengthening 20/719 81/18722 1.94377769153867e-11 1.66300980276087e-09 HNRNPA1/RAD51/AURKB/PTGES3/CCT5/NHP2/HSP90AB1/HNRNPA2B1/HSP90AA1/CCT2/PKIB/CCT8/CCT3/CCT7/PARP1/NOP10/CCT6A/CCT4/TCP1/RFC1 20 GO:0140694 non-membrane-bounded organelle assembly 44/719 367/18722 2.15657641090376e-11 1.80496069173467e-09 TUBB/CENPW/CENPN/CSRP2/LSM3/PRC1/RPLP0/NPM1/RPSA/RPL23A/RPS5/RPS3/RPL3/RPS19/RPL6/AURKB/RPS23/RPS15/RPL24/RPL11/RPS14/RPL5/RPL10/CENPK/CCNB2/LSM4/CDC20/ACTG1/KRT19/TPX2/RPS28/KRT8/AURKA/CENPH/HAUS1/C1QBP/MRPS7/EIF6/MRPL20/MRPL22/MZT1/BRIX1/MRTO4/SMC3 44 GO:2000573 positive regulation of DNA biosynthetic process 18/719 66/18722 3.25230658651931e-11 2.66412348044667e-09 PCNA/HNRNPA1/AURKB/RFC2/PTGES3/RFC4/RFC3/CCT5/HSP90AB1/HSP90AA1/CCT2/PKIB/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 18 GO:1904667 negative regulation of ubiquitin protein ligase activity 9/719 12/18722 3.43212782101077e-11 2.75285252310239e-09 MAD2L1/RPS15/RPL11/RPS7/RPL37/RPL5/RPS20/RPL23/BAG2 9 GO:1904851 positive regulation of establishment of protein localization to telomere 8/719 10/18722 1.91456036430857e-10 1.50429742909959e-08 CCT5/CCT2/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 8 GO:0000819 sister chromatid segregation 30/719 202/18722 2.05310712796153e-10 1.58089248853038e-08 UBE2C/NUSAP1/PTTG1/RAN/TOP2A/MAD2L1/PRC1/AURKB/ANAPC11/CDT1/ZWINT/FEN1/CENPK/NUF2/CDC6/CDC20/CCNB1/RAD51C/RMI2/TUBG1/BUB3/NUDC/LCMT1/SMC2/SMC4/PHB2/PSMG2/ANAPC15/NAA10/SMC3 30 GO:0140014 mitotic nuclear division 36/719 287/18722 4.22600014860156e-10 3.19021579845412e-08 UBE2C/NUSAP1/RANBP1/PTTG1/RAN/MAD2L1/PRC1/AURKB/RPL24/ANAPC11/CDT1/ZWINT/UBE2S/CENPK/NUF2/CDC6/CDC20/CCNB1/TPX2/AURKA/TUBG1/AURKAIP1/BUB3/UBE2I/NUDC/LCMT1/SMC2/SMC4/PHB2/PSMG2/PIN1/ANAPC15/MZT1/NAA10/NSFL1C/SMC3 36 GO:0051444 negative regulation of ubiquitin-protein transferase activity 10/719 19/18722 4.42801302809489e-10 3.2784327227241e-08 MAD2L1/RPS15/RPL11/RPS7/RPL37/RPL5/RPS20/PARK7/RPL23/BAG2 10 GO:0051052 regulation of DNA metabolic process 41/719 359/18722 4.71269340719463e-10 3.423371625981e-08 PCNA/HMGB1/NPM1/HNRNPA1/RPS3/RAD51/AURKB/CDT1/DEK/RAD51AP1/RFC2/PTGES3/RFC4/NUCKS1/KPNA2/RFC3/ANXA3/CCT5/RMI2/HSP90AB1/HNRNPA2B1/RPA2/HNRNPD/UBE2N/HSP90AA1/CCT2/PKIB/CCT8/ALYREF/CCT3/SUB1/CCT7/MIS18A/PARP1/CCT6A/CCT4/TFDP1/PPP4C/TCP1/BAX/USP1 41 GO:2000278 regulation of DNA biosynthetic process 21/719 106/18722 5.15866919902027e-10 3.67794007707927e-08 PCNA/HNRNPA1/AURKB/RFC2/PTGES3/RFC4/RFC3/CCT5/HSP90AB1/HNRNPA2B1/HNRNPD/HSP90AA1/CCT2/PKIB/CCT8/CCT3/CCT7/CCT6A/CCT4/TFDP1/TCP1 21 GO:0071103 DNA conformation change 36/719 290/18722 5.64788237185687e-10 3.95351766029981e-08 HMGB2/HMGB1/NUSAP1/CDK1/CENPW/NASP/TOP2A/NPM1/RAD51/HMGA1/ASF1B/RFC2/DNAJC9/CCNB1/MCM7/RFC4/SSBP1/RFC3/HELLS/BANF1/HAT1/ANP32B/MCM5/HNRNPA2B1/HMGB3/NAP1L1/SET/XRCC6/ITGB3BP/MCM4/MCM3/SMC2/MIS18A/SMC4/NAA10/RUVBL1 36 GO:0007004 telomere maintenance via telomerase 17/719 69/18722 6.5593920163469e-10 4.36739497250593e-08 HNRNPA1/AURKB/PTGES3/CCT5/NHP2/HSP90AB1/HSP90AA1/CCT2/PKIB/CCT8/CCT3/CCT7/NOP10/CCT6A/CCT4/TCP1/RFC1 17 GO:0070203 regulation of establishment of protein localization to telomere 8/719 11/18722 6.78316188950885e-10 4.36739497250593e-08 CCT5/CCT2/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 8 GO:1904869 regulation of protein localization to Cajal body 8/719 11/18722 6.78316188950885e-10 4.36739497250593e-08 CCT5/CCT2/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 8 GO:1904871 positive regulation of protein localization to Cajal body 8/719 11/18722 6.78316188950885e-10 4.36739497250593e-08 CCT5/CCT2/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 8 GO:0006457 protein folding 30/719 212/18722 6.80632982728196e-10 4.36739497250593e-08 PPIA/HSPE1/PTGES3/CCT5/HSP90AB1/ARL2/PDCD5/HSPD1/HSP90AA1/CCT2/NUDC/CCT8/BAG2/TBCA/CCT3/PPIF/PPIL1/PPIH/CCT7/PFDN2/MKKS/PPIC/CCT6A/CCT4/PFDN4/AHSA1/VBP1/TCP1/PFDN1/TTC1 30 GO:0006271 DNA strand elongation involved in DNA replication 9/719 15/18722 7.03614677935971e-10 4.4408467377926e-08 PCNA/MCM7/RFC4/RFC3/POLD2/MCM4/MCM3/POLD3/POLE3 9 GO:0042274 ribosomal small subunit biogenesis 17/719 73/18722 1.68352621788306e-09 1.04541547400803e-07 NPM1/RPSA/RPS5/RPS16/RPS6/RPS19/RPS8/RPS15/RPS25/RPS14/RPS7/RPS24/RPS17/RPS28/SNU13/MRPS7/LSM6 17 GO:0000027 ribosomal large subunit assembly 11/719 27/18722 1.84643160849608e-09 1.12837487185872e-07 RPLP0/RPL23A/RPL3/RPL6/RPL24/RPL11/RPL5/RPL10/MRPL20/BRIX1/MRTO4 11 GO:0070202 regulation of establishment of protein localization to chromosome 8/719 12/18722 1.96630601043242e-09 1.12989225972609e-07 CCT5/CCT2/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 8 GO:1903405 protein localization to nuclear body 8/719 12/18722 1.96630601043242e-09 1.12989225972609e-07 CCT5/CCT2/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 8 GO:1904816 positive regulation of protein localization to chromosome, telomeric region 8/719 12/18722 1.96630601043242e-09 1.12989225972609e-07 CCT5/CCT2/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 8 GO:1904867 protein localization to Cajal body 8/719 12/18722 1.96630601043242e-09 1.12989225972609e-07 CCT5/CCT2/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 8 GO:0034660 ncRNA metabolic process 48/719 485/18722 2.0216131651054e-09 1.14458980671409e-07 RPL35/RPL14/RPL7A/RPS16/RPS6/RPS19/RPL10A/RPS8/RPL26/RPS15/RPS25/RPL11/RPS14/RPS7/RPS24/RPL27/RPL5/RPL7/RPL35A/PA2G4/RPS17/TRMT112/RPS28/NHP2/SNU13/HNRNPA2B1/EXOSC8/TPRKB/POP7/POLR3K/TSEN34/EIF6/PIH1D1/LSM6/MPHOSPH6/RPP30/EBNA1BP2/SSB/METTL5/FBL/NOP10/HRAS/BRIX1/HSD17B10/NOP56/IMP3/PIN4/MRTO4 48 GO:0000280 nuclear division 45/719 439/18722 2.19070968798642e-09 1.22235250706488e-07 UBE2C/NUSAP1/RANBP1/PTTG1/RAN/TOP2A/MAD2L1/PRC1/RAD51/MND1/AURKB/RPL24/ANAPC11/CDT1/RAD51AP1/ZWINT/UBE2S/CENPK/CCNB2/NUF2/CKS2/CDC6/CDC20/CCNB1/TPX2/AURKA/CCNE1/UBB/RAD51C/TUBG1/AURKAIP1/BUB3/UBE2I/NUDC/LCMT1/SMC2/SMC4/PHB2/PSMG2/PIN1/ANAPC15/MZT1/NAA10/NSFL1C/SMC3 45 GO:0006278 RNA-dependent DNA biosynthetic process 17/719 75/18722 2.63027417167261e-09 1.44665079441993e-07 HNRNPA1/AURKB/PTGES3/CCT5/NHP2/HSP90AB1/HSP90AA1/CCT2/PKIB/CCT8/CCT3/CCT7/NOP10/CCT6A/CCT4/TCP1/RFC1 17 GO:0022616 DNA strand elongation 10/719 22/18722 2.79097532706585e-09 1.51341619847937e-07 PCNA/MCM7/RFC4/NUCKS1/RFC3/POLD2/MCM4/MCM3/POLD3/POLE3 10 GO:0006261 DNA-dependent DNA replication 24/719 151/18722 3.350179980765e-09 1.79141568415906e-07 PCNA/GMNN/RAD51/HMGA1/CDT1/RFC2/FEN1/CDC6/MCM7/RFC4/NUCKS1/SSBP1/RFC3/CCNE1/ORC6/MCM5/POLD2/MCM4/STOML2/MCM3/ALYREF/POLD3/POLE3/RFC1 24 GO:0051054 positive regulation of DNA metabolic process 28/719 201/18722 3.61504321353779e-09 1.90656388659185e-07 PCNA/HMGB1/HNRNPA1/RPS3/RAD51/AURKB/RAD51AP1/RFC2/PTGES3/RFC4/RFC3/ANXA3/CCT5/HSP90AB1/HNRNPA2B1/HNRNPD/UBE2N/HSP90AA1/CCT2/PKIB/CCT8/CCT3/CCT7/PARP1/CCT6A/CCT4/TCP1/BAX 28 GO:0000070 mitotic sister chromatid segregation 25/719 168/18722 6.3643058748674e-09 3.31115913759993e-07 UBE2C/NUSAP1/PTTG1/RAN/MAD2L1/PRC1/AURKB/ANAPC11/CDT1/ZWINT/CENPK/NUF2/CDC6/CDC20/CCNB1/TUBG1/BUB3/NUDC/LCMT1/SMC2/SMC4/PSMG2/ANAPC15/NAA10/SMC3 25 GO:1904358 positive regulation of telomere maintenance via telomere lengthening 12/719 37/18722 7.19563668100143e-09 3.69376016291407e-07 HNRNPA1/AURKB/CCT5/HNRNPA2B1/CCT2/PKIB/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 12 GO:1904814 regulation of protein localization to chromosome, telomeric region 8/719 14/18722 1.11381914967969e-08 5.51363445580582e-07 CCT5/CCT2/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 8 GO:1990173 protein localization to nucleoplasm 8/719 14/18722 1.11381914967969e-08 5.51363445580582e-07 CCT5/CCT2/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 8 GO:2001252 positive regulation of chromosome organization 17/719 82/18722 1.1170480196178e-08 5.51363445580582e-07 HNRNPA1/AURKB/CDT1/FEN1/SSBP1/CCT5/HNRNPA2B1/HNRNPD/CCT2/PKIB/CCT8/CCT3/CCT7/DNMT1/CCT6A/CCT4/TCP1 17 GO:1901798 positive regulation of signal transduction by p53 class mediator 10/719 25/18722 1.27045293897428e-08 6.19144786715313e-07 RPL26/RPS15/RPL11/RPS7/RPL37/RPS20/RPL23/UBB/EIF5A/EEF1E1 10 GO:0048285 organelle fission 46/719 488/18722 2.00418739728555e-08 9.64515184943673e-07 UBE2C/NUSAP1/RANBP1/PTTG1/RAN/TOP2A/MAD2L1/PRC1/RAD51/MND1/AURKB/RPL24/ANAPC11/CDT1/RAD51AP1/ZWINT/UBE2S/CENPK/CCNB2/NUF2/CKS2/CDC6/CDC20/CCNB1/TPX2/AURKA/CCNE1/UBB/RAD51C/TUBG1/AURKAIP1/BUB3/UBE2I/NUDC/LCMT1/SMC2/SMC4/PHB2/PSMG2/PIN1/ANAPC15/MZT1/BNIP3/NAA10/NSFL1C/SMC3 46 GO:0050821 protein stabilization 26/719 191/18722 2.12248301603148e-08 1.00883451996558e-06 GAPDH/NPM1/PFN1/RPL11/RPS7/RPL5/PTGES3/PARK7/RPL23/CCT5/HSP90AB1/HSPD1/HSP90AA1/CCT2/CCT8/BAG2/CCT3/PHB/CCT7/PHB2/TAF9/SUMO1/CCT6A/PIN1/CCT4/TCP1 26 GO:0032543 mitochondrial translation 16/719 76/18722 2.39062740648121e-08 1.12242872133569e-06 MRPL51/UQCC2/MRPS15/C1QBP/MRPS7/MRPL57/MRPS21/CHCHD1/MRPS6/MRPS34/MRPL16/MRPL52/MRPS16/COA3/MRPS12/MRPS14 16 GO:0140053 mitochondrial gene expression 19/719 108/18722 2.66779199729167e-08 1.23746978187626e-06 MRPL51/UQCC2/MRPS15/C1QBP/MRPS7/MRPL57/MRPS21/CHCHD1/MRPS6/MRPS34/MRPL12/MRPL16/MRPL52/MRPS16/COA3/HSD17B10/MRPS12/TFAM/MRPS14 19 GO:0032212 positive regulation of telomere maintenance via telomerase 11/719 34/18722 3.16785740477037e-08 1.45193464385309e-06 HNRNPA1/AURKB/CCT5/CCT2/PKIB/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 11 GO:0098813 nuclear chromosome segregation 32/719 281/18722 4.1594174347468e-08 1.88397142632649e-06 UBE2C/NUSAP1/PTTG1/RAN/TOP2A/MAD2L1/PRC1/AURKB/ANAPC11/CDT1/ZWINT/FEN1/CENPK/NUF2/CDC6/CDC20/CCNB1/CCNE1/RAD51C/RMI2/TUBG1/BUB3/NUDC/ECT2/LCMT1/SMC2/SMC4/PHB2/PSMG2/ANAPC15/NAA10/SMC3 32 GO:0070200 establishment of protein localization to telomere 8/719 16/18722 4.45733967666867e-08 1.99543694827609e-06 CCT5/CCT2/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 8 GO:0032392 DNA geometric change 17/719 90/18722 4.83392796211768e-08 2.139152029213e-06 HMGB2/HMGB1/TOP2A/RAD51/HMGA1/RFC2/MCM7/RFC4/SSBP1/RFC3/MCM5/HNRNPA2B1/HMGB3/XRCC6/MCM4/MCM3/RUVBL1 17 GO:0071824 protein-DNA complex subunit organization 29/719 241/18722 5.38782336359549e-08 2.35717272157303e-06 HMGB2/HMGB1/GMNN/CENPW/CENPN/NASP/NPM1/RAD51/HMGA1/CDT1/ASF1B/CENPK/DNAJC9/RPL23/CENPH/HELLS/HAT1/ANP32B/RAD51C/NAP1L1/SET/ITGB3BP/PIH1D1/GTF2A2/MIS18A/TAF9/SUPT16H/ANP32E/POLE3 29 GO:0032206 positive regulation of telomere maintenance 13/719 52/18722 5.64514681969104e-08 2.44200171413601e-06 HNRNPA1/AURKB/CCT5/HNRNPA2B1/HNRNPD/CCT2/PKIB/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 13 GO:0044772 mitotic cell cycle phase transition 41/719 424/18722 5.93598974726111e-08 2.53928450299503e-06 UBE2C/CDK1/CALM2/NASP/MAD2L1/RPS6/AURKB/RPL26/RPL24/ANAPC11/CDT1/CCNA2/CDKN3/ZWINT/CLSPN/UBE2S/CCNB2/CALM1/CKS2/CDC6/CCNB1/AURKA/CCNE1/RAD51C/RPA2/BUB3/EZH2/TRIAP1/CDKN2A/LCMT1/APEX1/CCND1/CDK4/PHB2/RNASEH2B/PSMG2/NAE1/ANAPC15/TFDP1/ENSA/CDK2AP2 41 GO:1901796 regulation of signal transduction by p53 class mediator 17/719 93/18722 8.01257387113869e-08 3.38993509932791e-06 NPM1/AURKB/RPL26/RPS15/RPL11/RPS7/RPL37/RPL5/RPS20/MIF/RPL23/AURKA/UBB/EIF5A/TRIAP1/EEF1E1/TAF9 17 GO:0090151 establishment of protein localization to mitochondrial membrane 10/719 30/18722 9.80789548413384e-08 4.10439104499079e-06 CALM1/PDCD5/HSP90AA1/ROMO1/TIMM8B/TIMM13/NDUFA13/TIMM10/TIMM8A/BAX 10 GO:0006413 translational initiation 19/719 118/18722 1.16427224313311e-07 4.8198367054435e-06 NPM1/RPS5/RPS3/RPS3A/RPL13A/RPS17/EIF3F/EIF2S2/PPP1CA/EIF3K/EIF3H/EIF6/EIF3I/EIF3M/EIF1AX/POLR2G/EIF3L/CDC123/MCTS1 19 GO:0043467 regulation of generation of precursor metabolites and energy 20/719 130/18722 1.18171745018618e-07 4.84001296086894e-06 HMGB1/CDK1/CHCHD2/CCNB1/PARK7/NDUFA4/PGAM1/PRELID1/UQCC2/ARL2/PPP1CA/COX17/PHLDA2/COX7A2/EIF6/PPIF/CISD1/PHB2/BNIP3/ISCU 20 GO:0031396 regulation of protein ubiquitination 26/719 210/18722 1.48476126369743e-07 6.01719038445802e-06 UBE2C/PPIA/MAD2L1/NPM1/RPS3/RPS2/RPS15/RPL11/RPS7/RPL37/RPL5/RPS20/UBE2S/CDC20/PARK7/RPL23/UBB/RBX1/HSP90AB1/UBE2L3/UBE2N/HSP90AA1/CAV1/SKP1/BAG2/PIN1 26 GO:0031100 animal organ regeneration 15/719 76/18722 1.61872737926236e-07 6.49177126058344e-06 TYMS/PCNA/CDK1/GSTP1/RPS16/RPS15/RPL19/CCNA2/AURKA/ANXA3/CSNK2B/EZH2/CCND1/ATIC/CDK4 15 GO:1900182 positive regulation of protein localization to nucleus 16/719 87/18722 1.76383946245806e-07 7.00080611387992e-06 CDK1/RAN/NPM1/PARK7/CCT5/HSP90AB1/CCT2/NUTF2/CCT8/ECT2/CCT3/CCT7/PARP1/CCT6A/CCT4/TCP1 16 GO:0051204 protein insertion into mitochondrial membrane 9/719 25/18722 2.03149943779969e-07 7.90027559144324e-06 PDCD5/HSP90AA1/ROMO1/TIMM8B/TIMM13/NDUFA13/TIMM10/TIMM8A/BAX 9 GO:0070199 establishment of protein localization to chromosome 9/719 25/18722 2.03149943779969e-07 7.90027559144324e-06 CCT5/CCT2/CCT8/PIH1D1/CCT3/CCT7/CCT6A/CCT4/TCP1 9 GO:1903320 regulation of protein modification by small protein conjugation or removal 28/719 242/18722 2.09047590486381e-07 8.04833223372567e-06 UBE2C/PPIA/MAD2L1/NPM1/RPS3/RPS2/RPS15/RPL11/RPS7/RPL37/RPL5/RPS20/UBE2S/CDC20/PARK7/RPL23/UBB/RBX1/HSP90AB1/UBE2L3/UBE2N/HSP90AA1/UBE2I/CAV1/SKP1/BAG2/SAE1/PIN1 28 GO:2001242 regulation of intrinsic apoptotic signaling pathway 22/719 164/18722 3.32835316606182e-07 1.26872868211267e-05 PPIA/ENO1/RPS3/RPL26/RPL11/TPT1/RPS7/MIF/SOD1/PARK7/HELLS/UBB/EIF5A/TRIAP1/CAV1/VDAC2/NDUFA13/PPIF/PARP1/TAF9/NDUFS3/BAX 22 GO:1904356 regulation of telomere maintenance via telomere lengthening 13/719 61/18722 4.24363005303083e-07 1.60176232393811e-05 HNRNPA1/AURKB/CCT5/HNRNPA2B1/CCT2/PKIB/CCT8/CCT3/CCT7/PARP1/CCT6A/CCT4/TCP1 13 GO:0010498 proteasomal protein catabolic process 43/719 490/18722 4.28768725620485e-07 1.60267921712511e-05 UBE2C/PBK/RPL11/ANAPC11/UBE2S/CDC20/PARK7/PSMA7/PSMB2/AURKA/PSMC3/UBB/PSMB1/PSMB6/PSMB3/RBX1/HSP90AB1/PSMB5/SUMO2/PSMB7/PSMA1/PSMA2/PSMA3/PSMA4/PSMD8/CAV1/PSMD14/PSMD7/PSMC1/EIF3H/SKP1/PSMD4/BAG2/NUDT15/PSMC5/PSMA5/PSMB4/TAF9/SUMO1/DDA1/RAD23A/NSFL1C/PSMD12 43 GO:0033045 regulation of sister chromatid segregation 14/719 72/18722 5.06863392914494e-07 1.87636929107769e-05 UBE2C/PTTG1/MAD2L1/AURKB/ANAPC11/CDT1/ZWINT/CDC6/CCNB1/RMI2/BUB3/LCMT1/PSMG2/ANAPC15 14 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen 8/719 21/18722 5.93941497742746e-07 2.17167216122021e-05 COX5A/COX7C/COX8A/COX4I1/COX5B/COX7A2/COX6C/CYCS 8 GO:0009262 deoxyribonucleotide metabolic process 11/719 44/18722 5.9791493269959e-07 2.17167216122021e-05 TYMS/DUT/RRM2/RRM1/DTYMK/DCTPP1/UNG/DNPH1/NUDT15/PNP/ADK 11 GO:0006275 regulation of DNA replication 17/719 107/18722 6.52821075859507e-07 2.34893564678421e-05 PCNA/CDK1/GMNN/CDT1/CCNA2/RFC2/CDC6/CACYBP/RFC4/NUCKS1/SSBP1/S100A11/RFC3/STOML2/HRAS/ID3/SMC3 17 GO:0006310 DNA recombination 31/719 305/18722 8.51067098556631e-07 3.03389660133614e-05 HMGB2/HMGB1/RPA3/TOP2A/GINS2/RAD51/MND1/RAD51AP1/FEN1/MCM7/NUCKS1/KPNA2/RAD51C/RMI2/MCM5/RPA2/UNG/HMGB3/UBE2N/TPRKB/HSPD1/XRCC6/MCM4/PSMD14/MCM3/ALYREF/ACTL6A/APEX1/PARP1/PPP4C/RUVBL1 31 GO:0065004 protein-DNA complex assembly 24/719 201/18722 8.66351227991024e-07 3.06004791538114e-05 HMGB2/HMGB1/GMNN/CENPW/CENPN/NASP/NPM1/RAD51/CDT1/ASF1B/CENPK/DNAJC9/CENPH/HELLS/HAT1/ANP32B/RAD51C/NAP1L1/SET/ITGB3BP/PIH1D1/GTF2A2/MIS18A/TAF9 24 GO:0010965 regulation of mitotic sister chromatid separation 13/719 65/18722 9.21201155657628e-07 3.2242040448017e-05 UBE2C/PTTG1/MAD2L1/AURKB/ANAPC11/CDT1/ZWINT/CDC6/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 13 GO:0001732 formation of cytoplasmic translation initiation complex 7/719 16/18722 1.01104529010659e-06 3.47653633129999e-05 EIF3F/EIF2S2/EIF3K/EIF3H/EIF3I/EIF3M/EIF3L 7 GO:0009123 nucleoside monophosphate metabolic process 14/719 76/18722 1.01135602365091e-06 3.47653633129999e-05 TYMS/DUT/TK1/DTYMK/PAICS/IMPDH2/DNPH1/GMPS/PNP/ATIC/APRT/AK2/UMPS/ADK 14 GO:0050657 nucleic acid transport 21/719 163/18722 1.20419173179947e-06 4.06678786616489e-05 RAN/NPM1/HNRNPA1/YBX1/SLBP/HNRNPA3/SRSF3/HNRNPA2B1/ENY2/MAGOH/EIF5A/RBM8A/NUTF2/NUP37/ALYREF/DDX39A/SSB/THOC6/MAGOHB/NXT1/MRPL18 21 GO:0050658 RNA transport 21/719 163/18722 1.20419173179947e-06 4.06678786616489e-05 RAN/NPM1/HNRNPA1/YBX1/SLBP/HNRNPA3/SRSF3/HNRNPA2B1/ENY2/MAGOH/EIF5A/RBM8A/NUTF2/NUP37/ALYREF/DDX39A/SSB/THOC6/MAGOHB/NXT1/MRPL18 21 GO:0051306 mitotic sister chromatid separation 13/719 67/18722 1.32613125772115e-06 4.3982053804284e-05 UBE2C/PTTG1/MAD2L1/AURKB/ANAPC11/CDT1/ZWINT/CDC6/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 13 GO:0051131 chaperone-mediated protein complex assembly 8/719 23/18722 1.33659747924707e-06 4.3982053804284e-05 PTGES3/HSP90AB1/HSPD1/PSMG1/HSP90AA1/CCT2/MKKS/PSMG2 8 GO:0051383 kinetochore organization 8/719 23/18722 1.33659747924707e-06 4.3982053804284e-05 CENPW/CENPN/CDT1/CENPK/NUF2/CENPH/SMC2/SMC4 8 GO:0006753 nucleoside phosphate metabolic process 42/719 497/18722 1.56658631457957e-06 5.11131975519605e-05 TYMS/DUT/GAPDH/RAN/LDHA/TK1/HINT1/ENO1/RRM2/TPI1/ALDOA/RRM1/DTYMK/NME1/PARK7/PKM/PGAM1/PAICS/MPC2/DCTPP1/IDH2/UNG/ARL2/IMPDH2/DNPH1/GMPS/STOML2/NUDT8/EIF6/NUDT15/PNP/QPRT/NUDT5/ATIC/PARP1/NME4/APRT/RNASEH2B/AK2/SLC25A1/UMPS/ADK 42 GO:0006979 response to oxidative stress 39/719 446/18722 1.61619633241824e-06 5.21675107574282e-05 PCNA/CDK1/LDHA/PPIA/PRDX2/GSTP1/RPS3/PAGE4/PRDX1/TXN/CHCHD2/PDLIM1/SOD1/DHFR/PARK7/PRDX6/PRDX5/NDUFA6/GPX4/RBX1/PSMB5/PSIP1/HSPD1/PRDX3/NDUFB4/ROMO1/NDUFS8/NUDT1/EZH2/NDUFA12/ECT2/NUDT15/APEX1/PPIF/PARP1/TXN2/HNRNPM/BNIP3/CYB5B 39 GO:0051236 establishment of RNA localization 21/719 166/18722 1.62600033529646e-06 5.21675107574282e-05 RAN/NPM1/HNRNPA1/YBX1/SLBP/HNRNPA3/SRSF3/HNRNPA2B1/ENY2/MAGOH/EIF5A/RBM8A/NUTF2/NUP37/ALYREF/DDX39A/SSB/THOC6/MAGOHB/NXT1/MRPL18 21 GO:0006839 mitochondrial transport 27/719 254/18722 1.83130879442259e-06 5.82689161861734e-05 SLC25A5/SLC25A6/SLC25A3/VDAC1/DYNLT1/MPC2/UBE2L3/PDCD5/HSPD1/HSP90AA1/ROMO1/UBL5/TIMM8B/STOML2/VDAC2/TIMM13/NDUFA13/SAE1/PPIF/TIMM10/TIMM8A/MRPL18/TOMM40/BNIP3/SLC25A1/BAX/MCUR1 27 GO:0032204 regulation of telomere maintenance 14/719 80/18722 1.92565393812302e-06 6.0768587391587e-05 HNRNPA1/AURKB/CCT5/HNRNPA2B1/HNRNPD/CCT2/PKIB/CCT8/CCT3/CCT7/PARP1/CCT6A/CCT4/TCP1 14 GO:0034502 protein localization to chromosome 15/719 92/18722 2.11117244580008e-06 6.60814139539048e-05 CDK1/AURKB/CDT1/CCT5/RPA2/BUB3/CCT2/EZH2/CCT8/PIH1D1/CCT3/CCT7/CCT6A/CCT4/TCP1 15 GO:0045039 protein insertion into mitochondrial inner membrane 6/719 12/18722 2.3814113878709e-06 7.3938982607282e-05 ROMO1/TIMM8B/TIMM13/NDUFA13/TIMM10/TIMM8A 6 GO:0030071 regulation of mitotic metaphase/anaphase transition 12/719 60/18722 2.41554049224803e-06 7.43986471612394e-05 UBE2C/MAD2L1/AURKB/ANAPC11/CDT1/ZWINT/CDC6/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 12 GO:0009117 nucleotide metabolic process 41/719 489/18722 2.54135571482663e-06 7.76525357308138e-05 TYMS/DUT/GAPDH/RAN/LDHA/HINT1/ENO1/RRM2/TPI1/ALDOA/RRM1/DTYMK/NME1/PARK7/PKM/PGAM1/PAICS/MPC2/DCTPP1/IDH2/UNG/ARL2/IMPDH2/DNPH1/GMPS/STOML2/NUDT8/EIF6/NUDT15/PNP/QPRT/NUDT5/ATIC/PARP1/NME4/APRT/RNASEH2B/AK2/SLC25A1/UMPS/ADK 41 GO:0072594 establishment of protein localization to organelle 37/719 422/18722 2.80628307957947e-06 8.50723610738657e-05 CDK1/RAN/CALM1/RPL23/KPNA2/CCT5/HSP90AB1/UBE2L3/PDCD5/HSPD1/SRP14/SRP9/HSP90AA1/ROMO1/UBL5/TIMM8B/CCT2/NUTF2/CCT8/ECT2/PIH1D1/TIMM13/NDUFA13/CCT3/SAE1/TIMM10/CCT7/NXT1/PHB2/SUMO1/TIMM8A/CCT6A/CCT4/TOMM40/TCP1/BAX/CSE1L 37 GO:1905818 regulation of chromosome separation 13/719 72/18722 3.1058973790857e-06 9.33171764629643e-05 UBE2C/PTTG1/MAD2L1/AURKB/ANAPC11/CDT1/ZWINT/CDC6/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 13 GO:0034655 nucleobase-containing compound catabolic process 36/719 407/18722 3.12673136720062e-06 9.33171764629643e-05 DUT/HINT1/NPM1/CARHSP1/FEN1/RNASEH2A/LSM4/YBX1/LSM2/LSM5/SLIRP/LSM7/DCTPP1/UNG/HNRNPD/EXOSC8/SERBP1/MAGOH/DNPH1/NUDT1/RBM8A/NUDT8/LSM6/NUDT15/PNP/RNASEH2C/APEX1/SSB/NUDT5/POLR2G/MAGOHB/HNRNPR/RNASEH2B/HNRNPM/BAX/MRTO4 36 GO:0009124 nucleoside monophosphate biosynthetic process 10/719 42/18722 3.1633089808488e-06 9.36826121251375e-05 TYMS/DUT/TK1/PAICS/IMPDH2/GMPS/ATIC/APRT/UMPS/ADK 10 GO:0007091 metaphase/anaphase transition of mitotic cell cycle 12/719 62/18722 3.47555161420978e-06 0.000102144074158074 UBE2C/MAD2L1/AURKB/ANAPC11/CDT1/ZWINT/CDC6/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 12 GO:1902850 microtubule cytoskeleton organization involved in mitosis 19/719 147/18722 3.6636805761609e-06 0.000106857350138026 STMN1/NUSAP1/RAN/MAD2L1/PRC1/SPC25/AURKB/NUF2/CDC20/CCNB1/TPX2/DYNLT1/AURKA/CENPH/TUBG1/NUDC/MZT1/NSFL1C/SMC3 19 GO:0002183 cytoplasmic translational initiation 9/719 34/18722 3.8230917840171e-06 0.000110668446379442 RPL13A/EIF3F/EIF2S2/EIF3K/EIF3H/EIF3I/EIF3M/EIF3L/MCTS1 9 GO:0033046 negative regulation of sister chromatid segregation 10/719 43/18722 3.98115092898817e-06 0.00011270169909268 PTTG1/MAD2L1/AURKB/CDT1/ZWINT/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 10 GO:0033048 negative regulation of mitotic sister chromatid segregation 10/719 43/18722 3.98115092898817e-06 0.00011270169909268 PTTG1/MAD2L1/AURKB/CDT1/ZWINT/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 10 GO:2000816 negative regulation of mitotic sister chromatid separation 10/719 43/18722 3.98115092898817e-06 0.00011270169909268 PTTG1/MAD2L1/AURKB/CDT1/ZWINT/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 10 GO:0000028 ribosomal small subunit assembly 7/719 19/18722 4.02525011670415e-06 0.0001131183426957 RPSA/RPS5/RPS19/RPS15/RPS14/RPS28/MRPS7 7 GO:1902099 regulation of metaphase/anaphase transition of cell cycle 12/719 63/18722 4.14501708602535e-06 0.000115639969428968 UBE2C/MAD2L1/AURKB/ANAPC11/CDT1/ZWINT/CDC6/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 12 GO:0032210 regulation of telomere maintenance via telomerase 11/719 53/18722 4.33676433008535e-06 0.00012011901202035 HNRNPA1/AURKB/CCT5/CCT2/PKIB/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 11 GO:0051098 regulation of binding 33/719 363/18722 4.48674588457947e-06 0.000123385511825935 STMN1/HMGB2/HMGB1/GMNN/RAN/CALM2/S100A10/AURKB/RPL11/TXN/CDT1/CALM1/NME1/NUCKS1/PARK7/ANXA2/AURKA/EDF1/HSP90AB1/PPP1CA/PHLDA2/CSNK2B/CAV1/BAG2/C4orf3/MDFI/PARP1/SUMO1/PCBD1/PIN1/ID1/ITGB1BP1/BAX 33 GO:0031647 regulation of protein stability 29/719 298/18722 4.54781717400906e-06 0.000124177986666205 GAPDH/NPM1/PFN1/RPL11/RPS7/RPL5/PTGES3/PARK7/RPL23/SERF2/AURKA/CCT5/HSP90AB1/HSPD1/HSP90AA1/CCT2/CCT8/BAG2/CCT3/PHB/CCT7/PHB2/TAF9/SUMO1/CCT6A/PIN1/CCT4/RAD23A/TCP1 29 GO:0072331 signal transduction by p53 class mediator 20/719 163/18722 4.60166842578807e-06 0.000124434994118418 HINT1/NPM1/AURKB/RPL26/RPS15/RPL11/RPS7/RPL37/RPL5/RPS20/MIF/RPL23/AURKA/UBB/EIF5A/TRIAP1/EEF1E1/PHLDA3/TAF9/BAX 20 GO:1900180 regulation of protein localization to nucleus 18/719 136/18722 4.68093447444198e-06 0.000124434994118418 CDK1/RAN/NPM1/PARK7/CCT5/HSP90AB1/CCT2/NUTF2/CCT8/ECT2/CCT3/CCT7/PARP1/SUMO1/CCT6A/PIN1/CCT4/TCP1 18 GO:2001251 negative regulation of chromosome organization 14/719 86/18722 4.6841818722753e-06 0.000124434994118418 PTTG1/TOP2A/MAD2L1/HNRNPA1/AURKB/CDT1/ZWINT/CCNB1/BUB3/LCMT1/PARP1/PSMG2/ANAPC15/NAA10 14 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 24/719 221/18722 4.68651276549885e-06 0.000124434994118418 PBK/RPL11/RPS7/RPL5/CDC20/PARK7/RPL23/AURKA/PSMC3/UBB/RBX1/HSP90AB1/SUMO2/CAV1/PSMD14/PSMC1/EIF3H/BAG2/NUDT15/PSMC5/TAF9/SUMO1/DDA1/RAD23A 24 GO:0097421 liver regeneration 9/719 35/18722 4.97219572475796e-06 0.000131116120139165 TYMS/PCNA/RPS16/RPS15/RPL19/AURKA/CSNK2B/EZH2/CCND1 9 GO:0015931 nucleobase-containing compound transport 24/719 222/18722 5.06817609055535e-06 0.000132737945228831 RAN/SLC25A5/NPM1/HNRNPA1/SLC25A6/YBX1/SLBP/HNRNPA3/SRSF3/HNRNPA2B1/ENY2/MAGOH/EIF5A/RBM8A/NUTF2/NUP37/ALYREF/DDX39A/SSB/THOC6/MAGOHB/NXT1/MRPL18/SLC29A1 24 GO:0044784 metaphase/anaphase transition of cell cycle 12/719 65/18722 5.83197163793052e-06 0.000151710073013733 UBE2C/MAD2L1/AURKB/ANAPC11/CDT1/ZWINT/CDC6/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 12 GO:1903362 regulation of cellular protein catabolic process 26/719 255/18722 6.08805235351663e-06 0.000157308735308987 PBK/RPL11/RPS7/RPL5/CDC20/PARK7/ANXA2/RPL23/AURKA/PSMC3/UBB/RBX1/HSP90AB1/SUMO2/HSP90AA1/CAV1/PSMD14/PSMC1/EIF3H/BAG2/NUDT15/PSMC5/TAF9/SUMO1/DDA1/RAD23A 26 GO:0051985 negative regulation of chromosome segregation 10/719 45/18722 6.17968002267557e-06 0.000157561378061596 PTTG1/MAD2L1/AURKB/CDT1/ZWINT/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 10 GO:1905819 negative regulation of chromosome separation 10/719 45/18722 6.17968002267557e-06 0.000157561378061596 PTTG1/MAD2L1/AURKB/CDT1/ZWINT/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 10 GO:0051168 nuclear export 19/719 154/18722 7.307038543302e-06 0.00018507959468232 RAN/NPM1/HNRNPA1/RPS15/TXN/PARK7/SRSF3/ANP32B/HNRNPA2B1/YWHAE/ENY2/NUTF2/EIF6/ALYREF/DDX39A/SSB/THOC6/NXT1/CSE1L 19 GO:0033047 regulation of mitotic sister chromatid segregation 10/719 46/18722 7.62689876661205e-06 0.000191918694453963 PTTG1/MAD2L1/AURKB/CDT1/ZWINT/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 10 GO:0034504 protein localization to nucleus 28/719 290/18722 7.68417334975009e-06 0.000192104333743752 CDK1/RAN/NPM1/RPL11/TXN/PARK7/RPL23/KPNA2/CCT5/HSP90AB1/YWHAE/ARL2/CCT2/NUTF2/CCT8/SKP1/ECT2/CCT3/CCT7/NXT1/PARP1/PHB2/SUMO1/CCT6A/PIN1/CCT4/TCP1/CSE1L 28 GO:0006323 DNA packaging 22/719 199/18722 8.69420110904427e-06 0.000215952737224648 HMGB2/HMGB1/NUSAP1/CDK1/CENPW/NASP/TOP2A/NPM1/ASF1B/DNAJC9/CCNB1/HELLS/BANF1/HAT1/ANP32B/NAP1L1/SET/ITGB3BP/SMC2/MIS18A/SMC4/NAA10 22 GO:0007093 mitotic cell cycle checkpoint signaling 17/719 129/18722 9.07085384738031e-06 0.000223864021233424 CDK1/MAD2L1/AURKB/RPL26/CDT1/ZWINT/CLSPN/CDC6/CCNB1/RPA2/BUB3/TRIAP1/LCMT1/CCND1/PSMG2/NAE1/ANAPC15 17 GO:0051983 regulation of chromosome segregation 14/719 91/18722 9.23564315200423e-06 0.000226479147358066 UBE2C/PTTG1/MAD2L1/AURKB/ANAPC11/CDT1/ZWINT/CDC6/CCNB1/RMI2/BUB3/LCMT1/PSMG2/ANAPC15 14 GO:0051972 regulation of telomerase activity 10/719 47/18722 9.35783866624632e-06 0.000228018085856434 AURKB/PTGES3/HSP90AB1/HNRNPA2B1/HNRNPD/HSP90AA1/CCT2/PKIB/CCT4/TCP1 10 GO:0046700 heterocycle catabolic process 37/719 445/18722 9.44764432557945e-06 0.000228018085856434 DUT/HINT1/NPM1/CARHSP1/FEN1/RNASEH2A/LSM4/YBX1/LSM2/LSM5/SLIRP/LSM7/DCTPP1/UNG/HNRNPD/EXOSC8/SERBP1/MAGOH/DNPH1/NUDT1/RBM8A/NUDT8/LSM6/NUDT15/PNP/RNASEH2C/APEX1/SSB/QPRT/NUDT5/POLR2G/MAGOHB/HNRNPR/RNASEH2B/HNRNPM/BAX/MRTO4 37 GO:0070198 protein localization to chromosome, telomeric region 8/719 29/18722 9.53530177217816e-06 0.000228018085856434 CCT5/CCT2/CCT8/CCT3/CCT7/CCT6A/CCT4/TCP1 8 GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 8/719 29/18722 9.53530177217816e-06 0.000228018085856434 RPL26/RPL11/RPS7/MIF/UBB/EIF5A/TRIAP1/TAF9 8 GO:1902600 proton transmembrane transport 19/719 157/18722 9.68800111353727e-06 0.000230239532636534 SLC25A5/UQCRH/SLC25A3/COX5A/UQCR10/COX8A/PARK7/NDUFA4/CYB5A/COX4I1/COX5B/COX7B/COX17/COX6B1/STOML2/UQCRFS1/PPIF/PHB2/CYC1 19 GO:0007094 mitotic spindle assembly checkpoint signaling 9/719 38/18722 1.03529961586163e-05 0.000241569910367714 MAD2L1/AURKB/CDT1/ZWINT/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 9 GO:0071173 spindle assembly checkpoint signaling 9/719 38/18722 1.03529961586163e-05 0.000241569910367714 MAD2L1/AURKB/CDT1/ZWINT/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 9 GO:0071174 mitotic spindle checkpoint signaling 9/719 38/18722 1.03529961586163e-05 0.000241569910367714 MAD2L1/AURKB/CDT1/ZWINT/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 9 GO:0061136 regulation of proteasomal protein catabolic process 21/719 187/18722 1.08687370475502e-05 0.000252076130319688 PBK/RPL11/CDC20/PARK7/AURKA/PSMC3/UBB/RBX1/HSP90AB1/SUMO2/CAV1/PSMD14/PSMC1/EIF3H/BAG2/NUDT15/PSMC5/TAF9/SUMO1/DDA1/RAD23A 21 GO:0045839 negative regulation of mitotic nuclear division 10/719 48/18722 1.14174583564189e-05 0.000263216854324628 MAD2L1/AURKB/CDT1/ZWINT/CCNB1/AURKAIP1/BUB3/LCMT1/PSMG2/ANAPC15 10 GO:0009263 deoxyribonucleotide biosynthetic process 6/719 15/18722 1.16820539455509e-05 0.000267713736252208 TYMS/DUT/RRM2/RRM1/DTYMK/ADK 6 GO:0034508 centromere complex assembly 8/719 30/18722 1.25673940517192e-05 0.000286298621888277 CENPW/CENPN/NASP/CENPK/CENPH/HELLS/ITGB3BP/MIS18A 8 GO:0044270 cellular nitrogen compound catabolic process 37/719 451/18722 1.27342866246293e-05 0.000288394138263663 DUT/HINT1/NPM1/CARHSP1/FEN1/RNASEH2A/LSM4/YBX1/LSM2/LSM5/SLIRP/LSM7/DCTPP1/UNG/HNRNPD/EXOSC8/SERBP1/MAGOH/DNPH1/NUDT1/RBM8A/NUDT8/LSM6/NUDT15/PNP/RNASEH2C/APEX1/SSB/QPRT/NUDT5/POLR2G/MAGOHB/HNRNPR/RNASEH2B/HNRNPM/BAX/MRTO4 37 GO:0031577 spindle checkpoint signaling 9/719 39/18722 1.300380954479e-05 0.000292775828932407 MAD2L1/AURKB/CDT1/ZWINT/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 9 GO:1901990 regulation of mitotic cell cycle phase transition 28/719 299/18722 1.36108184908846e-05 0.000304660762732011 UBE2C/CDK1/MAD2L1/AURKB/RPL26/ANAPC11/CDT1/ZWINT/CLSPN/CDC6/CCNB1/AURKA/RAD51C/RPA2/BUB3/EZH2/TRIAP1/LCMT1/APEX1/CCND1/CDK4/PHB2/RNASEH2B/PSMG2/NAE1/ANAPC15/TFDP1/CDK2AP2 28 GO:0006081 cellular aldehyde metabolic process 11/719 60/18722 1.52690009769823e-05 0.000339801466828796 TPI1/PARK7/AKR7A2/IDH2/ADH5/ALDH7A1/PNKD/GLO1/TALDO1/ESD/GRHPR 11 GO:0044839 cell cycle G2/M phase transition 18/719 148/18722 1.54175090549585e-05 0.000341134539434426 CDK1/CALM2/NPM1/AURKB/CCNA2/CLSPN/CCNB2/CALM1/CDC6/CCNB1/AURKA/RAD51C/LCMT1/CCND1/CDK4/RNASEH2B/NAE1/ENSA 18 GO:0031397 negative regulation of protein ubiquitination 13/719 83/18722 1.57164909964636e-05 0.000345762801922198 PPIA/MAD2L1/RPS3/RPS15/RPL11/RPS7/RPL37/RPL5/RPS20/PARK7/RPL23/CAV1/BAG2 13 GO:0007339 binding of sperm to zona pellucida 9/719 40/18722 1.62119696119863e-05 0.000350652151719929 ALDOA/CCT5/CCT2/VDAC2/CCT8/CCT3/CCT7/CCT4/TCP1 9 GO:0009394 2'-deoxyribonucleotide metabolic process 9/719 40/18722 1.62119696119863e-05 0.000350652151719929 TYMS/DUT/DTYMK/DCTPP1/UNG/DNPH1/NUDT15/PNP/ADK 9 GO:0045841 negative regulation of mitotic metaphase/anaphase transition 9/719 40/18722 1.62119696119863e-05 0.000350652151719929 MAD2L1/AURKB/CDT1/ZWINT/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 9 GO:0051443 positive regulation of ubiquitin-protein transferase activity 8/719 31/18722 1.6371861757859e-05 0.000352132222166241 UBE2C/RPS2/UBE2S/CDC20/UBE2L3/UBE2N/SKP1/PIN1 8 GO:0000387 spliceosomal snRNP assembly 10/719 50/18722 1.67300769254711e-05 0.000357837756461466 SNRPD1/SNRPG/SNRPE/SNRPF/SNRPD2/LSM4/SNRPB/SNRPD3/LSM2/SNRPC 10 GO:0051304 chromosome separation 14/719 96/18722 1.73339635584116e-05 0.000368705854695495 UBE2C/PTTG1/TOP2A/MAD2L1/AURKB/ANAPC11/CDT1/ZWINT/CDC6/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 14 GO:0031055 chromatin remodeling at centromere 5/719 10/18722 1.7678299333712e-05 0.000373964024366985 CENPW/NASP/HELLS/ITGB3BP/MIS18A 5 GO:0032508 DNA duplex unwinding 13/719 84/18722 1.79503148764379e-05 0.000377643236471508 TOP2A/RAD51/HMGA1/RFC2/MCM7/RFC4/SSBP1/RFC3/MCM5/XRCC6/MCM4/MCM3/RUVBL1 13 GO:0045727 positive regulation of translation 17/719 136/18722 1.84071578497602e-05 0.000385149770225962 NPM1/RPL26/RPS4X/RPL5/PKM/RPS9/UQCC2/HNRNPD/C1QBP/EIF5A/EIF6/METTL5/POLR2G/CDK4/RBM3/COA3/CDC123 17 GO:1901361 organic cyclic compound catabolic process 39/719 495/18722 1.88703066734761e-05 0.000391855146241181 DUT/HINT1/NPM1/CARHSP1/FEN1/RNASEH2A/LSM4/YWHAH/YBX1/LSM2/LSM5/COMT/SLIRP/LSM7/DCTPP1/UNG/HNRNPD/EXOSC8/SERBP1/MAGOH/DNPH1/NUDT1/RBM8A/NUDT8/LSM6/NUDT15/PNP/RNASEH2C/APEX1/SSB/QPRT/NUDT5/POLR2G/MAGOHB/HNRNPR/RNASEH2B/HNRNPM/BAX/MRTO4 39 GO:0097193 intrinsic apoptotic signaling pathway 27/719 288/18722 1.8931183688535e-05 0.000391855146241181 PPIA/HINT1/ENO1/RPS3/RPL26/RPL11/TPT1/RPS7/MIF/SOD1/PARK7/HELLS/UBB/CD24/EIF5A/TRIAP1/CAV1/VDAC2/PHLDA3/NDUFA13/PPIF/PARP1/TAF9/HRAS/BNIP3/NDUFS3/BAX 27 GO:1901293 nucleoside phosphate biosynthetic process 25/719 256/18722 1.92352882491249e-05 0.000396020640423159 TYMS/DUT/TK1/ENO1/RRM2/ALDOA/RRM1/DTYMK/NME1/PAICS/MPC2/IDH2/IMPDH2/GMPS/STOML2/PNP/QPRT/ATIC/PARP1/NME4/APRT/AK2/SLC25A1/UMPS/ADK 25 GO:2001233 regulation of apoptotic signaling pathway 31/719 356/18722 2.03744156678163e-05 0.000417242022984537 HMGB2/PPIA/PRDX2/GSTP1/ENO1/SLC25A5/RPS3/RPL26/RPL11/TPT1/RPS7/MIF/SOD1/PARK7/PRELID1/HELLS/UBB/BCL2L12/PPP1CA/EIF5A/TRIAP1/CAV1/VDAC2/PIH1D1/NDUFA13/PPIF/FAIM/PARP1/TAF9/NDUFS3/BAX 31 GO:0009116 nucleoside metabolic process 11/719 62/18722 2.11199382018915e-05 0.000430220963371863 TK1/ERH/DTYMK/DNPH1/NUDT1/PNP/ATIC/NME4/APRT/UMPS/ADK 11 GO:0000724 double-strand break repair via homologous recombination 17/719 138/18722 2.23167587264529e-05 0.000452208005772862 RPA3/GINS2/RAD51/RAD51AP1/FEN1/MCM7/NUCKS1/RAD51C/RMI2/MCM5/RPA2/UBE2N/MCM4/PSMD14/MCM3/PARP1/PPP4C 17 GO:0019692 deoxyribose phosphate metabolic process 9/719 42/18722 2.46806154473878e-05 0.000494897757668975 TYMS/DUT/DTYMK/DCTPP1/UNG/DNPH1/NUDT15/PNP/ADK 9 GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle 9/719 42/18722 2.46806154473878e-05 0.000494897757668975 MAD2L1/AURKB/CDT1/ZWINT/CCNB1/BUB3/LCMT1/PSMG2/ANAPC15 9 GO:0000725 recombinational repair 17/719 140/18722 2.69481384927395e-05 0.000536669532043568 RPA3/GINS2/RAD51/RAD51AP1/FEN1/MCM7/NUCKS1/RAD51C/RMI2/MCM5/RPA2/UBE2N/MCM4/PSMD14/MCM3/PARP1/PPP4C 17 GO:0009200 deoxyribonucleoside triphosphate metabolic process 6/719 17/18722 2.70425686276499e-05 0.000536669532043568 TYMS/DUT/DTYMK/DCTPP1/NUDT15/ADK 6 GO:0019439 aromatic compound catabolic process 37/719 467/18722 2.72815667262382e-05 0.000538636061005216 DUT/HINT1/NPM1/CARHSP1/FEN1/RNASEH2A/LSM4/YBX1/LSM2/LSM5/COMT/SLIRP/LSM7/DCTPP1/UNG/HNRNPD/EXOSC8/SERBP1/MAGOH/DNPH1/NUDT1/RBM8A/NUDT8/LSM6/NUDT15/PNP/RNASEH2C/APEX1/SSB/NUDT5/POLR2G/MAGOHB/HNRNPR/RNASEH2B/HNRNPM/BAX/MRTO4 37 GO:0007051 spindle organization 20/719 184/18722 2.82197277138339e-05 0.000554316080093166 STMN1/TUBB/RAN/PRC1/SPC25/RPS3/AURKB/CCNB2/NUF2/CDC20/CCNB1/TPX2/AURKA/CENPH/HAUS1/TUBG1/NUDC/NTMT1/MZT1/SMC3 20 GO:0006417 regulation of translation 37/719 468/18722 2.85665886228481e-05 0.000558281046690178 TYMS/GAPDH/NPM1/RPS3/RPL26/RPL13A/RPL22/RPS4X/RPS14/RPL5/RPL10/PA2G4/YBX1/DHFR/PKM/RPS9/UQCC2/HNRNPD/PPP1CA/EXOSC8/SRP9/C1QBP/MAGOH/EIF5A/RBM8A/EIF3K/NCL/EIF3H/EIF6/METTL5/POLR2G/CDK4/RBM3/HNRNPR/COA3/MRPL13/CDC123 37 GO:1901657 glycosyl compound metabolic process 13/719 88/18722 2.99128659010657e-05 0.000581639059187388 TK1/ERH/DTYMK/AKR7A2/DNPH1/NUDT1/AKR1B1/PNP/ATIC/NME4/APRT/UMPS/ADK 13 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 5/719 11/18722 3.13845816745652e-05 0.000607189142950132 UQCRH/UQCRQ/UQCR10/CYCS/CYC1 5 GO:0006270 DNA replication initiation 8/719 34/18722 3.40262625921251e-05 0.000651746820794437 CDT1/CDC6/MCM7/CCNE1/ORC6/MCM5/MCM4/MCM3 8 GO:0051973 positive regulation of telomerase activity 8/719 34/18722 3.40262625921251e-05 0.000651746820794437 AURKB/PTGES3/HSP90AB1/HSP90AA1/CCT2/PKIB/CCT4/TCP1 8 GO:0009126 purine nucleoside monophosphate metabolic process 9/719 44/18722 3.66356850711277e-05 0.000698254393682384 PAICS/IMPDH2/DNPH1/GMPS/PNP/ATIC/APRT/AK2/ADK 9 GO:0007006 mitochondrial membrane organization 15/719 116/18722 3.78198188887647e-05 0.000713756385890901 SLC25A5/CALM1/DYNLT1/PDCD5/HSP90AA1/ROMO1/TIMM8B/VDAC2/TIMM13/NDUFA13/PPIF/TIMM10/TIMM8A/BNIP3/BAX 15 GO:1990748 cellular detoxification 15/719 116/18722 3.78198188887647e-05 0.000713756385890901 GSTO1/PRDX2/GSTP1/PRDX1/TXN/SOD1/DHFR/PARK7/PRDX6/PRDX5/GPX4/PRDX3/ADH5/TXNDC17/ESD 15 GO:0051099 positive regulation of binding 19/719 173/18722 3.84947814898356e-05 0.000722950774321302 STMN1/HMGB2/HMGB1/GMNN/RAN/CALM2/S100A10/RPL11/TXN/CDT1/CALM1/NME1/PARK7/ANXA2/EDF1/HSP90AB1/CAV1/PARP1/PIN1 19 GO:0090068 positive regulation of cell cycle process 23/719 236/18722 4.22969999407749e-05 0.000790502183359142 UBE2C/NUSAP1/CDK1/RANBP1/MAD2L1/NPM1/AURKB/ANAPC11/CDT1/RAD51AP1/FEN1/CDC6/CCNB1/AURKA/RAD51C/EZH2/ECT2/APEX1/CCND1/CDK4/PHB2/TFDP1/NSFL1C 23 GO:0045454 cell redox homeostasis 8/719 35/18722 4.2634874997271e-05 0.000792967481833301 PRDX2/PRDX1/TXN/PRDX6/PRDX5/PRDX3/APEX1/TXN2 8 GO:0051784 negative regulation of nuclear division 10/719 56/18722 4.711363812182e-05 0.00087205532100484 MAD2L1/AURKB/CDT1/ZWINT/CCNB1/AURKAIP1/BUB3/LCMT1/PSMG2/ANAPC15 10 GO:0009165 nucleotide biosynthetic process 24/719 254/18722 4.78474607780288e-05 0.000879199094672147 TYMS/DUT/ENO1/RRM2/ALDOA/RRM1/DTYMK/NME1/PAICS/MPC2/IDH2/IMPDH2/GMPS/STOML2/PNP/QPRT/ATIC/PARP1/NME4/APRT/AK2/SLC25A1/UMPS/ADK 24 GO:0000302 response to reactive oxygen species 22/719 222/18722 4.79563142548444e-05 0.000879199094672147 PCNA/CDK1/LDHA/PRDX2/GSTP1/RPS3/PRDX1/TXN/SOD1/DHFR/PARK7/PRDX5/RBX1/HSPD1/PRDX3/ROMO1/EZH2/ECT2/NUDT15/APEX1/PPIF/BNIP3 22 GO:0042176 regulation of protein catabolic process 32/719 391/18722 5.08412128957837e-05 0.000927671420136338 MAD2L1/PBK/RPL11/RPS7/EEF1A1/RPL5/CDC20/PARK7/ANXA2/RPL23/AURKA/PSMC3/UBB/RBX1/HSP90AB1/SUMO2/HSP90AA1/CAV1/PSMD14/PSMC1/EIF3H/BAG2/NUDT15/PSMC5/NDUFA13/SNX3/PHB/TAF9/SUMO1/PIN1/DDA1/RAD23A 32 GO:0000727 double-strand break repair via break-induced replication 5/719 12/18722 5.2101131879347e-05 0.000946176215733424 GINS2/MCM7/MCM5/MCM4/MCM3 5 GO:0017004 cytochrome complex assembly 8/719 36/18722 5.29862166114213e-05 0.000957732084290949 COX20/UQCC2/COX17/COA4/UQCRFS1/COX14/COA3/COA6 8 GO:0009168 purine ribonucleoside monophosphate biosynthetic process 6/719 19/18722 5.55064177313982e-05 0.000998596767597584 PAICS/IMPDH2/GMPS/ATIC/APRT/ADK 6 GO:0007052 mitotic spindle organization 15/719 120/18722 5.64021283346906e-05 0.00100531571337296 STMN1/RAN/PRC1/SPC25/AURKB/NUF2/CDC20/CCNB1/TPX2/AURKA/CENPH/TUBG1/NUDC/MZT1/SMC3 15 GO:0072655 establishment of protein localization to mitochondrion 15/719 120/18722 5.64021283346906e-05 0.00100531571337296 CALM1/UBE2L3/PDCD5/HSPD1/HSP90AA1/ROMO1/UBL5/TIMM8B/TIMM13/NDUFA13/SAE1/TIMM10/TIMM8A/TOMM40/BAX 15 GO:1901991 negative regulation of mitotic cell cycle phase transition 19/719 179/18722 6.15148142712628e-05 0.00109139186610305 CDK1/MAD2L1/AURKB/RPL26/CDT1/ZWINT/CLSPN/CDC6/CCNB1/RPA2/BUB3/EZH2/TRIAP1/LCMT1/CCND1/PSMG2/NAE1/ANAPC15/CDK2AP2 19 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 10/719 58/18722 6.44283738266346e-05 0.00113784054693827 RPS3/RPL26/RPL11/RPS7/SOD1/PARK7/UBB/EIF5A/CAV1/BAX 10 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 13/719 95/18722 6.79664899857902e-05 0.00119484468696481 PPIA/MAD2L1/RPS3/RPS15/RPL11/RPS7/RPL37/RPL5/RPS20/PARK7/RPL23/CAV1/BAG2 13 GO:0000470 maturation of LSU-rRNA 7/719 28/18722 6.9925451984892e-05 0.00122369540973561 RPL35/RPL7A/RPL10A/RPL7/NHP2/SNU13/EIF6 7 GO:0000086 G2/M transition of mitotic cell cycle 16/719 137/18722 7.41694424972013e-05 0.00129209209780192 CDK1/CALM2/AURKB/CCNA2/CLSPN/CALM1/CDC6/CCNB1/AURKA/RAD51C/LCMT1/CCND1/CDK4/RNASEH2B/NAE1/ENSA 16 GO:0006401 RNA catabolic process 25/719 278/18722 7.5400877997716e-05 0.00129865290968693 NPM1/CARHSP1/FEN1/RNASEH2A/LSM4/YBX1/LSM2/LSM5/SLIRP/LSM7/HNRNPD/EXOSC8/SERBP1/MAGOH/RBM8A/LSM6/RNASEH2C/APEX1/SSB/POLR2G/MAGOHB/HNRNPR/RNASEH2B/HNRNPM/MRTO4 25 GO:0035036 sperm-egg recognition 9/719 48/18722 7.5557987472694e-05 0.00129865290968693 ALDOA/CCT5/CCT2/VDAC2/CCT8/CCT3/CCT7/CCT4/TCP1 9 GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 9/719 48/18722 7.5557987472694e-05 0.00129865290968693 PBK/RPL11/RPS7/RPL5/PARK7/RPL23/HSP90AB1/EIF3H/TAF9 9 GO:0009636 response to toxic substance 24/719 262/18722 7.82081112462462e-05 0.00133822768132466 TYMS/MT2A/CDK1/GSTO1/PRDX2/GSTP1/RAD51/PRDX1/TXN/UBA52/CCNB1/SOD1/DHFR/PARK7/PRDX6/PRDX5/GPX4/PRDX3/ADH5/SRSF9/TXNDC17/CDK4/ESD/BAX 24 GO:0045787 positive regulation of cell cycle 27/719 313/18722 8.04940359374185e-05 0.00137124795734098 CKS1B/UBE2C/NUSAP1/CDK1/RANBP1/MAD2L1/NPM1/AURKB/RPS15A/ANAPC11/CDT1/RAD51AP1/FEN1/CKS2/CDC6/CCNB1/AURKA/RAD51C/EZH2/ECT2/APEX1/CCND1/CDK4/PHB2/TFDP1/RAD23A/NSFL1C 27 GO:0007088 regulation of mitotic nuclear division 14/719 110/18722 8.11531634511423e-05 0.00137638625236519 NUSAP1/MAD2L1/AURKB/ANAPC11/CDT1/ZWINT/CCNB1/AURKA/AURKAIP1/BUB3/LCMT1/PSMG2/PIN1/ANAPC15 14 GO:0097237 cellular response to toxic substance 15/719 124/18722 8.25489462597476e-05 0.00139391861008784 GSTO1/PRDX2/GSTP1/PRDX1/TXN/SOD1/DHFR/PARK7/PRDX6/PRDX5/GPX4/PRDX3/ADH5/TXNDC17/ESD 15 GO:0051783 regulation of nuclear division 16/719 139/18722 8.83108409277971e-05 0.00148035025007257 NUSAP1/MAD2L1/AURKB/ANAPC11/CDT1/RAD51AP1/ZWINT/CDC20/CCNB1/AURKA/AURKAIP1/BUB3/LCMT1/PSMG2/PIN1/ANAPC15 16 GO:0007346 regulation of mitotic cell cycle 35/719 457/18722 8.84365084458938e-05 0.00148035025007257 CKS1B/UBE2C/NUSAP1/CDK1/RPA3/MAD2L1/AURKB/RPL26/ANAPC11/CDT1/ZWINT/CLSPN/CKS2/CDC6/CCNB1/AURKA/RAD51C/RPA2/YWHAE/AURKAIP1/BUB3/EZH2/TRIAP1/LCMT1/APEX1/CCND1/CDK4/PHB2/RNASEH2B/PSMG2/PIN1/NAE1/ANAPC15/TFDP1/CDK2AP2 35 GO:0043457 regulation of cellular respiration 9/719 49/18722 8.94409051462007e-05 0.00149068175243668 PARK7/PRELID1/UQCC2/ARL2/COX7A2/PPIF/CISD1/BNIP3/ISCU 9 GO:0070585 protein localization to mitochondrion 15/719 125/18722 9.05434066636922e-05 0.00150255222265179 CALM1/UBE2L3/PDCD5/HSPD1/HSP90AA1/ROMO1/UBL5/TIMM8B/TIMM13/NDUFA13/SAE1/TIMM10/TIMM8A/TOMM40/BAX 15 GO:0000075 cell cycle checkpoint signaling 18/719 169/18722 9.11518034937987e-05 0.00150615640966148 CDK1/MAD2L1/AURKB/RPL26/CDT1/ZWINT/CLSPN/CDC6/CCNB1/RPA2/BUB3/TRIAP1/LCMT1/CCND1/RNASEH2B/PSMG2/NAE1/ANAPC15 18 GO:0034614 cellular response to reactive oxygen species 17/719 155/18722 9.86461131696139e-05 0.00162033722937393 PCNA/CDK1/PRDX2/RPS3/PRDX1/TXN/SOD1/DHFR/PARK7/PRDX5/PRDX3/ROMO1/EZH2/ECT2/APEX1/PPIF/BNIP3 17 GO:0009141 nucleoside triphosphate metabolic process 14/719 112/18722 9.89037010137334e-05 0.00162033722937393 TYMS/DUT/RAN/ENO1/ALDOA/DTYMK/NME1/DCTPP1/IMPDH2/STOML2/NUDT15/PARP1/NME4/ADK 14 GO:0009127 purine nucleoside monophosphate biosynthetic process 6/719 21/18722 0.000103946231550914 0.0016957330147077 PAICS/IMPDH2/GMPS/ATIC/APRT/ADK 6 GO:0006913 nucleocytoplasmic transport 26/719 301/18722 0.000106070209473747 0.00171584162384003 CDK1/RAN/NPM1/HNRNPA1/RPS15/TXN/PARK7/RPL23/KPNA2/SRSF3/ANP32B/HSP90AB1/HNRNPA2B1/YWHAE/ENY2/NUTF2/EIF6/ECT2/ALYREF/DDX39A/SSB/THOC6/NXT1/PHB2/SUMO1/CSE1L 26 GO:0051169 nuclear transport 26/719 301/18722 0.000106070209473747 0.00171584162384003 CDK1/RAN/NPM1/HNRNPA1/RPS15/TXN/PARK7/RPL23/KPNA2/SRSF3/ANP32B/HSP90AB1/HNRNPA2B1/YWHAE/ENY2/NUTF2/EIF6/ECT2/ALYREF/DDX39A/SSB/THOC6/NXT1/PHB2/SUMO1/CSE1L 26 GO:0006626 protein targeting to mitochondrion 13/719 100/18722 0.000116176992064888 0.00187147037426703 UBE2L3/PDCD5/HSPD1/HSP90AA1/ROMO1/UBL5/TIMM8B/TIMM13/NDUFA13/SAE1/TIMM10/TIMM8A/TOMM40 13 GO:1901998 toxin transport 8/719 40/18722 0.000117578096067072 0.00188614862440928 CCT5/CCT2/CCT8/CCT3/CCT7/CCT4/BNIP3/TCP1 8 GO:0098869 cellular oxidant detoxification 13/719 101/18722 0.000128739702619309 0.0020566301040844 GSTO1/PRDX2/GSTP1/PRDX1/TXN/SOD1/DHFR/PARK7/PRDX6/PRDX5/GPX4/PRDX3/TXNDC17 13 GO:1901989 positive regulation of cell cycle phase transition 14/719 115/18722 0.000131827723880433 0.00209725924355234 UBE2C/CDK1/NPM1/ANAPC11/CDT1/CDC6/CCNB1/RAD51C/EZH2/APEX1/CCND1/CDK4/PHB2/TFDP1 14 GO:0009167 purine ribonucleoside monophosphate metabolic process 8/719 41/18722 0.000141216479583525 0.00223257189174046 PAICS/IMPDH2/GMPS/PNP/ATIC/APRT/AK2/ADK 8 GO:0051028 mRNA transport 15/719 130/18722 0.000141492867944071 0.00223257189174046 HNRNPA1/SLBP/HNRNPA3/SRSF3/HNRNPA2B1/ENY2/MAGOH/EIF5A/RBM8A/NUTF2/NUP37/ALYREF/DDX39A/THOC6/MAGOHB 15 GO:0071426 ribonucleoprotein complex export from nucleus 11/719 76/18722 0.000146194427268035 0.00228800221537373 RAN/NPM1/RPS15/SRSF3/HNRNPA2B1/ENY2/EIF6/ALYREF/DDX39A/SSB/THOC6 11 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 11/719 76/18722 0.000146194427268035 0.00228800221537373 HINT1/RPL26/RPL11/RPS7/MIF/UBB/EIF5A/TRIAP1/PHLDA3/TAF9/BAX 11 GO:0071166 ribonucleoprotein complex localization 11/719 77/18722 0.000164739161928566 0.00256779665354242 RAN/NPM1/RPS15/SRSF3/HNRNPA2B1/ENY2/EIF6/ALYREF/DDX39A/SSB/THOC6 11 GO:0000413 protein peptidyl-prolyl isomerization 8/719 42/18722 0.000168636682909675 0.00261794850484778 PPIA/FKBP3/PPIF/PPIL1/PPIH/PPIC/PIN1/PIN4 8 GO:0034250 positive regulation of cellular amide metabolic process 17/719 162/18722 0.000169737329930431 0.00262445269169542 NPM1/RPL26/RPS4X/RPL5/PKM/RPS9/UQCC2/HNRNPD/C1QBP/EIF5A/EIF6/METTL5/POLR2G/CDK4/RBM3/COA3/CDC123 17 GO:0051101 regulation of DNA binding 14/719 118/18722 0.000173844325101979 0.00267720260657048 HMGB2/HMGB1/CALM2/TXN/CDT1/CALM1/NME1/PARK7/EDF1/CSNK2B/MDFI/PARP1/SUMO1/ID1 14 GO:0006268 DNA unwinding involved in DNA replication 5/719 15/18722 0.000179432103455968 0.00273048853085169 RAD51/HMGA1/MCM7/SSBP1/MCM4 5 GO:0098760 response to interleukin-7 5/719 15/18722 0.000179432103455968 0.00273048853085169 HMGB1/YBX1/HSPD1/ATIC/STIP1 5 GO:0098761 cellular response to interleukin-7 5/719 15/18722 0.000179432103455968 0.00273048853085169 HMGB1/YBX1/HSPD1/ATIC/STIP1 5 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 17/719 164/18722 0.000196909761825031 0.00298465583868649 PBK/RPL11/RPS7/RPL5/CDC20/PARK7/RPL23/AURKA/RBX1/HSP90AB1/SUMO2/CAV1/EIF3H/TAF9/SUMO1/DDA1/RAD23A 17 GO:0006284 base-excision repair 8/719 43/18722 0.000200288522325152 0.00302396396451701 PCNA/HMGB1/RPA3/RPS3/FEN1/RPA2/UNG/APEX1 8 GO:0009156 ribonucleoside monophosphate biosynthetic process 7/719 33/18722 0.000213458649114715 0.00318533255461881 PAICS/IMPDH2/GMPS/ATIC/APRT/UMPS/ADK 7 GO:1901976 regulation of cell cycle checkpoint 7/719 33/18722 0.000213458649114715 0.00318533255461881 MAD2L1/CDT1/CCNB1/RPA2/LCMT1/RNASEH2B/ANAPC15 7 GO:1903715 regulation of aerobic respiration 7/719 33/18722 0.000213458649114715 0.00318533255461881 PARK7/UQCC2/ARL2/COX7A2/PPIF/BNIP3/ISCU 7 GO:1901992 positive regulation of mitotic cell cycle phase transition 12/719 93/18722 0.000226289582387716 0.00336055248049145 UBE2C/CDK1/ANAPC11/CDT1/CDC6/CCNB1/RAD51C/APEX1/CCND1/CDK4/PHB2/TFDP1 12 GO:0042177 negative regulation of protein catabolic process 14/719 121/18722 0.000226946401279942 0.00336055248049145 MAD2L1/PBK/RPL11/RPS7/RPL5/PARK7/ANXA2/RPL23/HSP90AB1/EIF3H/SNX3/PHB/TAF9/PIN1 14 GO:0021762 substantia nigra development 8/719 44/18722 0.000236655819492713 0.00349090001933695 CALM2/CALM1/YWHAH/DYNLL1/YWHAE/COX6B1/YWHAQ/NDUFS3 8 GO:0098754 detoxification 16/719 152/18722 0.000252125196063057 0.00367234575796412 MT2A/GSTO1/PRDX2/GSTP1/PRDX1/TXN/SOD1/DHFR/PARK7/PRDX6/PRDX5/GPX4/PRDX3/ADH5/TXNDC17/ESD 16 GO:0090231 regulation of spindle checkpoint 5/719 16/18722 0.000252771850872855 0.00367234575796412 MAD2L1/CDT1/CCNB1/LCMT1/ANAPC15 5 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint 5/719 16/18722 0.000252771850872855 0.00367234575796412 MAD2L1/CDT1/CCNB1/LCMT1/ANAPC15 5 GO:1903504 regulation of mitotic spindle checkpoint 5/719 16/18722 0.000252771850872855 0.00367234575796412 MAD2L1/CDT1/CCNB1/LCMT1/ANAPC15 5 GO:0043388 positive regulation of DNA binding 9/719 56/18722 0.00025958960077525 0.00374874870193625 HMGB2/HMGB1/CALM2/TXN/CALM1/NME1/PARK7/EDF1/PARP1 9 GO:0034724 DNA replication-independent nucleosome organization 7/719 34/18722 0.000259978156731683 0.00374874870193625 CENPW/NASP/ASF1B/HAT1/ITGB3BP/MIS18A/SUPT16H 7 GO:0006325 chromatin organization 31/719 409/18722 0.000263969567081102 0.00379210012411285 HMGB2/HMGB1/CENPW/HMGN2/NASP/NPM1/HMGA1/DEK/ASF1B/DNAJC9/NUCKS1/HELLS/GPX4/HAT1/ANP32B/HMGN1/NAP1L1/SET/CBX3/ITGB3BP/RBBP7/EZH2/PIH1D1/ACTL6A/NUDT5/MIS18A/DNMT1/SUPT16H/RUVBL1/ANP32E/POLE3 31 GO:0072527 pyrimidine-containing compound metabolic process 11/719 82/18722 0.000290258563566736 0.00415425825179157 TYMS/DUT/TK1/RRM1/ERH/DTYMK/NME1/DCTPP1/UNG/NME4/UMPS 11 GO:0009132 nucleoside diphosphate metabolic process 14/719 124/18722 0.000293443945681815 0.00418429329953699 GAPDH/LDHA/ENO1/TPI1/ALDOA/DTYMK/NME1/PKM/PGAM1/ARL2/EIF6/NUDT5/NME4/AK2 14 GO:0009147 pyrimidine nucleoside triphosphate metabolic process 6/719 25/18722 0.000297518730413287 0.00420134388650396 TYMS/DUT/DTYMK/NME1/DCTPP1/NME4 6 GO:0033119 negative regulation of RNA splicing 6/719 25/18722 0.000297518730413287 0.00420134388650396 NPM1/RPS13/RPS26/SAP18/C1QBP/SRSF9 6 GO:0051205 protein insertion into membrane 9/719 57/18722 0.000297913475588463 0.00420134388650396 PDCD5/HSP90AA1/ROMO1/TIMM8B/TIMM13/NDUFA13/TIMM10/TIMM8A/BAX 9 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 31/719 412/18722 0.000299639479197692 0.00421026275515006 UBE2C/PBK/RPL11/ANAPC11/UBE2S/CDC20/PARK7/AURKA/PSMC3/PSMB3/RBX1/HSP90AB1/PSMB5/SUMO2/PSMA2/PSMD8/CAV1/PSMD14/PSMD7/PSMC1/EIF3H/SKP1/PSMD4/PSMC5/PSMA5/TAF9/SUMO1/DDA1/RAD23A/NSFL1C/PSMD12 31 GO:2001020 regulation of response to DNA damage stimulus 20/719 219/18722 0.000313011178347778 0.00438215649686889 PCNA/HMGB1/NPM1/RPS3/RAD51/RPL26/TPT1/DEK/MIF/RAD51AP1/RMI2/RPA2/UBE2N/TRIAP1/EEF1E1/PARP1/TAF9/RNASEH2B/PPP4C/USP1 20 GO:0090329 regulation of DNA-dependent DNA replication 8/719 46/18722 0.000325646453712552 0.004542532053599 PCNA/GMNN/CDT1/RFC2/RFC4/SSBP1/RFC3/STOML2 8 GO:0009161 ribonucleoside monophosphate metabolic process 9/719 58/18722 0.000340798494279411 0.00471969137761055 PAICS/IMPDH2/GMPS/PNP/ATIC/APRT/AK2/UMPS/ADK 9 GO:0018208 peptidyl-proline modification 9/719 58/18722 0.000340798494279411 0.00471969137761055 PPIA/FKBP3/PPIF/PPIL1/PPIH/NTMT1/PPIC/PIN1/PIN4 9 GO:0006338 chromatin remodeling 22/719 255/18722 0.000357079685927066 0.00492744369469249 HMGB2/CENPW/NASP/NPM1/HMGA1/ASF1B/DNAJC9/HELLS/HAT1/ANP32B/NAP1L1/SET/CBX3/ITGB3BP/PIH1D1/ACTL6A/NUDT5/MIS18A/SUPT16H/RUVBL1/ANP32E/POLE3 22 GO:0006405 RNA export from nucleus 11/719 84/18722 0.000359242142839952 0.00493957946404934 RAN/NPM1/HNRNPA1/SRSF3/HNRNPA2B1/ENY2/ALYREF/DDX39A/SSB/THOC6/NXT1 11 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 12/719 98/18722 0.000370676331704436 0.00507866148420669 PPIA/ENO1/TPT1/MIF/PARK7/HELLS/TRIAP1/VDAC2/NDUFA13/PPIF/TAF9/NDUFS3 12 GO:0008535 respiratory chain complex IV assembly 6/719 26/18722 0.000374312553913715 0.0050844360979745 COX20/COX17/COA4/COX14/COA3/COA6 6 GO:0000492 box C/D snoRNP assembly 4/719 10/18722 0.000376380334525385 0.0050844360979745 SNU13/PIH1D1/TAF9/RUVBL1 4 GO:0032070 regulation of deoxyribonuclease activity 4/719 10/18722 0.000376380334525385 0.0050844360979745 PCNA/HMGB1/NPM1/RPS3 4 GO:1904668 positive regulation of ubiquitin protein ligase activity 4/719 10/18722 0.000376380334525385 0.0050844360979745 UBE2C/UBE2S/CDC20/SKP1 4 GO:0006165 nucleoside diphosphate phosphorylation 12/719 99/18722 0.000407364630581289 0.00548375464244043 GAPDH/LDHA/ENO1/TPI1/ALDOA/DTYMK/NME1/PKM/PGAM1/ARL2/EIF6/NME4 12 GO:2001234 negative regulation of apoptotic signaling pathway 20/719 224/18722 0.000419773488258446 0.00563110776932061 HMGB2/PPIA/PRDX2/GSTP1/ENO1/SLC25A5/TPT1/MIF/PARK7/PRELID1/HELLS/TRIAP1/VDAC2/PIH1D1/NDUFA13/PPIF/FAIM/TAF9/NDUFS3/BAX 20 GO:1903829 positive regulation of cellular protein localization 23/719 276/18722 0.000434111405688059 0.00580322538853829 CDK1/RAN/NPM1/CDT1/PARK7/CCT5/HSP90AB1/UBE2L3/PDCD5/UBL5/CCT2/NUTF2/CCT8/ECT2/CCT3/SAE1/CCT7/PARP1/CCT6A/CCT4/HRAS/ITGB1BP1/TCP1 23 GO:0010948 negative regulation of cell cycle process 24/719 294/18722 0.0004438763117421 0.00591323114258506 CDK1/PTTG1/MAD2L1/NPM1/AURKB/RPL26/CDT1/ZWINT/CLSPN/CDC6/CCNB1/RPA2/AURKAIP1/BUB3/EZH2/TRIAP1/LCMT1/CCND1/RNASEH2B/PSMG2/NAE1/ANAPC15/NAA10/CDK2AP2 24 GO:0033260 nuclear DNA replication 7/719 37/18722 0.000450203795374763 0.00597684349032013 PCNA/GMNN/RAD51/CDT1/FEN1/MCM4/MCM3 7 GO:0045116 protein neddylation 5/719 18/18722 0.000465124376770915 0.00615370739026812 RPL11/RPL5/NEDD8/RBX1/NAE1 5 GO:0046939 nucleotide phosphorylation 12/719 101/18722 0.000489993249300612 0.00646052743084711 GAPDH/LDHA/ENO1/TPI1/ALDOA/DTYMK/NME1/PKM/PGAM1/ARL2/EIF6/NME4 12 GO:1902749 regulation of cell cycle G2/M phase transition 12/719 102/18722 0.000536331584407918 0.00702338979581798 CDK1/NPM1/AURKB/CLSPN/CDC6/CCNB1/AURKA/RAD51C/CCND1/CDK4/RNASEH2B/NAE1 12 GO:1990542 mitochondrial transmembrane transport 12/719 102/18722 0.000536331584407918 0.00702338979581798 SLC25A5/SLC25A6/SLC25A3/VDAC1/MPC2/HSPD1/ROMO1/STOML2/MRPL18/TOMM40/SLC25A1/MCUR1 12 GO:1901987 regulation of cell cycle phase transition 29/719 390/18722 0.000560903358315653 0.00732026416784835 UBE2C/CDK1/MAD2L1/NPM1/AURKB/RPL26/ANAPC11/CDT1/ZWINT/CLSPN/CDC6/CCNB1/AURKA/RAD51C/RPA2/BUB3/EZH2/TRIAP1/LCMT1/APEX1/CCND1/CDK4/PHB2/RNASEH2B/PSMG2/NAE1/ANAPC15/TFDP1/CDK2AP2 29 GO:1903363 negative regulation of cellular protein catabolic process 10/719 75/18722 0.000569730506321128 0.00741034611262278 PBK/RPL11/RPS7/RPL5/PARK7/ANXA2/RPL23/HSP90AB1/EIF3H/TAF9 10 GO:0035404 histone-serine phosphorylation 4/719 11/18722 0.000573520764725852 0.00743452843163141 AURKB/CCNB1/AURKA/VRK1 4 GO:0006220 pyrimidine nucleotide metabolic process 8/719 50/18722 0.00058542647959867 0.00756339579347275 TYMS/DUT/DTYMK/NME1/DCTPP1/UNG/NME4/UMPS 8 GO:1904951 positive regulation of establishment of protein localization 25/719 319/18722 0.00062194730718293 0.00800835161422837 CDK1/RAN/PPIA/PHPT1/DYNLL1/MPC2/CCT5/ANP32B/HSP90AB1/UBE2L3/YWHAE/PDCD5/UBL5/CCT2/NUTF2/CCT8/ECT2/CCT3/SAE1/CCT7/CCT6A/CCT4/HRAS/ITGB1BP1/TCP1 25 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 14/719 134/18722 0.000648776893465798 0.00832597013281108 PBK/RPL11/CDC20/PARK7/AURKA/RBX1/HSP90AB1/SUMO2/CAV1/EIF3H/TAF9/SUMO1/DDA1/RAD23A 14 GO:0006402 mRNA catabolic process 20/719 232/18722 0.00065659333194066 0.00839828680389216 NPM1/CARHSP1/LSM4/YBX1/LSM2/LSM5/LSM7/HNRNPD/EXOSC8/SERBP1/MAGOH/RBM8A/LSM6/APEX1/SSB/POLR2G/MAGOHB/HNRNPR/HNRNPM/MRTO4 20 GO:0019693 ribose phosphate metabolic process 29/719 396/18722 0.000715092541280588 0.00910473630892353 GAPDH/RAN/LDHA/HINT1/ENO1/TPI1/ALDOA/NME1/PKM/PGAM1/PAICS/MPC2/ARL2/IMPDH2/GMPS/STOML2/NUDT8/EIF6/PNP/NUDT5/ATIC/PARP1/NME4/APRT/RNASEH2B/AK2/SLC25A1/UMPS/ADK 29 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process 9/719 64/18722 0.000718384085223829 0.00910473630892353 PBK/RPL11/RPS7/RPL5/PARK7/RPL23/HSP90AB1/EIF3H/TAF9 9 GO:0006302 double-strand break repair 21/719 251/18722 0.000719492338900496 0.00910473630892353 HMGB2/HMGB1/RPA3/GINS2/RAD51/DEK/RAD51AP1/FEN1/MCM7/NUCKS1/RAD51C/RMI2/MCM5/RPA2/UBE2N/XRCC6/MCM4/PSMD14/MCM3/PARP1/PPP4C 21 GO:0034728 nucleosome organization 16/719 167/18722 0.000721284304992644 0.00910473630892353 HMGB2/CENPW/NASP/NPM1/HMGA1/ASF1B/DNAJC9/HAT1/ANP32B/NAP1L1/SET/ITGB3BP/MIS18A/SUPT16H/ANP32E/POLE3 16 GO:0045740 positive regulation of DNA replication 7/719 40/18722 0.000737820063559186 0.00928303021144728 PCNA/CDK1/CDT1/CACYBP/SSBP1/STOML2/HRAS 7 GO:0045930 negative regulation of mitotic cell cycle 20/719 235/18722 0.000771330220922025 0.00967303371514591 CDK1/MAD2L1/AURKB/RPL26/CDT1/ZWINT/CLSPN/CDC6/CCNB1/RPA2/AURKAIP1/BUB3/EZH2/TRIAP1/LCMT1/CCND1/PSMG2/NAE1/ANAPC15/CDK2AP2 20 GO:0000491 small nucleolar ribonucleoprotein complex assembly 4/719 12/18722 0.000834230581149106 0.0102613026754762 SNU13/PIH1D1/TAF9/RUVBL1 4 GO:0009265 2'-deoxyribonucleotide biosynthetic process 4/719 12/18722 0.000834230581149106 0.0102613026754762 TYMS/DUT/DTYMK/ADK 4 GO:0043248 proteasome assembly 4/719 12/18722 0.000834230581149106 0.0102613026754762 POMP/PSMG1/PSMG2/PSMD11 4 GO:0046185 aldehyde catabolic process 4/719 12/18722 0.000834230581149106 0.0102613026754762 PARK7/ADH5/PNKD/ESD 4 GO:0046385 deoxyribose phosphate biosynthetic process 4/719 12/18722 0.000834230581149106 0.0102613026754762 TYMS/DUT/DTYMK/ADK 4 GO:1903599 positive regulation of autophagy of mitochondrion 4/719 12/18722 0.000834230581149106 0.0102613026754762 SLC25A5/PARK7/VDAC1/BNIP3 4 GO:0006221 pyrimidine nucleotide biosynthetic process 6/719 30/18722 0.000847055020748611 0.0103201323730448 TYMS/DUT/DTYMK/NME1/NME4/UMPS 6 GO:0009264 deoxyribonucleotide catabolic process 6/719 30/18722 0.000847055020748611 0.0103201323730448 DUT/DCTPP1/UNG/DNPH1/NUDT15/PNP 6 GO:1902751 positive regulation of cell cycle G2/M phase transition 6/719 30/18722 0.000847055020748611 0.0103201323730448 CDK1/NPM1/CCNB1/RAD51C/CCND1/CDK4 6 GO:0071478 cellular response to radiation 17/719 186/18722 0.000851566825700527 0.0103423731197067 PCNA/PBK/NPM1/RAD51/AURKB/RPL26/RAD51AP1/NUCKS1/EEF1D/ADIRF/XRCC6/TRIAP1/ECT2/POLD3/PARP1/HRAS/BAX 17 GO:0044786 cell cycle DNA replication 7/719 41/18722 0.000860650213201233 0.0104198217635998 PCNA/GMNN/RAD51/CDT1/FEN1/MCM4/MCM3 7 GO:0010389 regulation of G2/M transition of mitotic cell cycle 11/719 94/18722 0.000944911525666022 0.0114041046201072 CDK1/AURKB/CLSPN/CDC6/CCNB1/AURKA/RAD51C/CCND1/CDK4/RNASEH2B/NAE1 11 GO:0010639 negative regulation of organelle organization 26/719 347/18722 0.000949661669095844 0.0114256169563094 STMN1/PTTG1/TOP2A/MAD2L1/SLC25A5/NPM1/HNRNPA1/PFN1/AURKB/CDT1/ZWINT/CCNB1/TPX2/PRELID1/AURKAIP1/BUB3/CKAP2/TRIAP1/LCMT1/PPIF/PARP1/MKKS/PSMG2/ANAPC15/BNIP3/NAA10 26 GO:0009259 ribonucleotide metabolic process 28/719 385/18722 0.000974238172160097 0.0116847880461569 GAPDH/RAN/LDHA/HINT1/ENO1/TPI1/ALDOA/NME1/PKM/PGAM1/PAICS/MPC2/ARL2/IMPDH2/GMPS/STOML2/NUDT8/EIF6/PNP/ATIC/PARP1/NME4/APRT/RNASEH2B/AK2/SLC25A1/UMPS/ADK 28 GO:0046386 deoxyribose phosphate catabolic process 6/719 31/18722 0.0010166361950574 0.0121554327669906 DUT/DCTPP1/UNG/DNPH1/NUDT15/PNP 6 GO:0009988 cell-cell recognition 9/719 68/18722 0.00112196761427276 0.0133732981887001 ALDOA/CCT5/CCT2/VDAC2/CCT8/CCT3/CCT7/CCT4/TCP1 9 GO:0042769 DNA damage response, detection of DNA damage 4/719 13/18722 0.00116855968476831 0.0138004748047791 RPS3/MRPS26/PARP1/USP1 4 GO:0110096 cellular response to aldehyde 4/719 13/18722 0.00116855968476831 0.0138004748047791 PARK7/AKR1B1/ADH5/ESD 4 GO:1905907 negative regulation of amyloid fibril formation 4/719 13/18722 0.00116855968476831 0.0138004748047791 PFDN2/PFDN4/VBP1/PFDN1 4 GO:0032069 regulation of nuclease activity 5/719 22/18722 0.00125852089307608 0.014727372153018 HMGB2/PCNA/HMGB1/NPM1/RPS3 5 GO:0033617 mitochondrial cytochrome c oxidase assembly 5/719 22/18722 0.00125852089307608 0.014727372153018 COX20/COX17/COA4/COX14/COA3 5 GO:0043486 histone exchange 5/719 22/18722 0.00125852089307608 0.014727372153018 CENPW/NASP/ITGB3BP/MIS18A/ANP32E 5 GO:1904029 regulation of cyclin-dependent protein kinase activity 11/719 98/18722 0.00133576514283791 0.0155839266664423 CKS1B/CCNA2/CDKN3/CCNB2/CKS2/CDC6/CCNB1/CCNE1/HSP90AB1/CDKN2A/CCND1 11 GO:0006333 chromatin assembly or disassembly 16/719 177/18722 0.00134193847332652 0.0156086499163357 HMGB2/HMGB1/CENPW/NASP/NPM1/HMGA1/ASF1B/DNAJC9/HELLS/HAT1/ANP32B/NAP1L1/SET/ITGB3BP/MIS18A/SUPT16H 16 GO:0006611 protein export from nucleus 8/719 57/18722 0.00142372061182833 0.0164667120825956 RAN/TXN/PARK7/ANP32B/YWHAE/NUTF2/NXT1/CSE1L 8 GO:0006336 DNA replication-independent nucleosome assembly 6/719 33/18722 0.00143281780458949 0.0164667120825956 CENPW/NASP/ASF1B/HAT1/ITGB3BP/MIS18A 6 GO:0071353 cellular response to interleukin-4 6/719 33/18722 0.00143281780458949 0.0164667120825956 TUBA1B/RPLP0/RPL3/HSP90AB1/IMPDH2/CDK4 6 GO:1904031 positive regulation of cyclin-dependent protein kinase activity 6/719 33/18722 0.00143281780458949 0.0164667120825956 CKS1B/CKS2/CDC6/CCNB1/HSP90AB1/CCND1 6 GO:1901800 positive regulation of proteasomal protein catabolic process 12/719 114/18722 0.00144524034083845 0.0165600455721072 CDC20/AURKA/PSMC3/RBX1/SUMO2/CAV1/PSMC1/BAG2/PSMC5/SUMO1/DDA1/RAD23A 12 GO:0006163 purine nucleotide metabolic process 28/719 396/18722 0.00148478633999755 0.0169626926082806 GAPDH/RAN/LDHA/HINT1/ENO1/TPI1/ALDOA/NME1/PKM/PGAM1/PAICS/MPC2/ARL2/IMPDH2/DNPH1/GMPS/STOML2/NUDT8/EIF6/NUDT15/PNP/ATIC/PARP1/NME4/APRT/AK2/SLC25A1/ADK 28 GO:0042542 response to hydrogen peroxide 14/719 146/18722 0.00150269235463315 0.017116466169638 PCNA/CDK1/LDHA/RPS3/TXN/SOD1/PARK7/HSPD1/PRDX3/EZH2/ECT2/APEX1/PPIF/BNIP3 14 GO:0009142 nucleoside triphosphate biosynthetic process 10/719 85/18722 0.00152642626171735 0.0173088120031675 TYMS/ENO1/ALDOA/DTYMK/NME1/IMPDH2/STOML2/PARP1/NME4/ADK 10 GO:0072521 purine-containing compound metabolic process 29/719 416/18722 0.00152857041066933 0.0173088120031675 GAPDH/RAN/LDHA/HINT1/ENO1/TPI1/ALDOA/NME1/PKM/PGAM1/PAICS/MPC2/ARL2/IMPDH2/DNPH1/GMPS/NUDT1/STOML2/NUDT8/EIF6/NUDT15/PNP/ATIC/PARP1/NME4/APRT/AK2/SLC25A1/ADK 29 GO:0009162 deoxyribonucleoside monophosphate metabolic process 5/719 23/18722 0.00155781028446466 0.0175881806310526 TYMS/DUT/TK1/DNPH1/PNP 5 GO:1901988 negative regulation of cell cycle phase transition 20/719 249/18722 0.00156375488838028 0.0176036734510646 CDK1/MAD2L1/AURKB/RPL26/CDT1/ZWINT/CLSPN/CDC6/CCNB1/RPA2/BUB3/EZH2/TRIAP1/LCMT1/CCND1/RNASEH2B/PSMG2/NAE1/ANAPC15/CDK2AP2 20 GO:0000054 ribosomal subunit export from nucleus 4/719 14/18722 0.0015865773905613 0.0177052839236551 RAN/NPM1/RPS15/EIF6 4 GO:0033750 ribosome localization 4/719 14/18722 0.0015865773905613 0.0177052839236551 RAN/NPM1/RPS15/EIF6 4 GO:0051984 positive regulation of chromosome segregation 4/719 14/18722 0.0015865773905613 0.0177052839236551 AURKB/CDT1/CDC6/CCNB1 4 GO:0009112 nucleobase metabolic process 6/719 34/18722 0.0016841405862733 0.0187397146160469 TYMS/RRM1/PAICS/GMPS/APRT/UMPS 6 GO:0031099 regeneration 17/719 198/18722 0.001690139050592 0.0187522632414386 TYMS/PCNA/CDK1/GSTP1/RPS16/RPS15/RPL19/CCNA2/CCNB1/DHFR/AURKA/ANXA3/CSNK2B/EZH2/CCND1/ATIC/CDK4 17 GO:0048024 regulation of mRNA splicing, via spliceosome 11/719 101/18722 0.00170873073239832 0.0188687760171936 NPM1/HNRNPA1/PRDX6/SRSF3/SAP18/C1QBP/MAGOH/RBM8A/NCL/SRSF9/RBM3 11 GO:0043484 regulation of RNA splicing 14/719 148/18722 0.00171044229350664 0.0188687760171936 NPM1/HNRNPA1/RPS13/RPS26/PRDX6/SRSF3/HNRNPF/SAP18/C1QBP/MAGOH/RBM8A/NCL/SRSF9/RBM3 14 GO:0009260 ribonucleotide biosynthetic process 16/719 182/18722 0.00179217842789163 0.0197139627068079 ENO1/ALDOA/NME1/PAICS/MPC2/IMPDH2/GMPS/STOML2/ATIC/PARP1/NME4/APRT/AK2/SLC25A1/UMPS/ADK 16 GO:0009219 pyrimidine deoxyribonucleotide metabolic process 5/719 24/18722 0.001906274044685 0.0208498723637421 TYMS/DUT/DTYMK/DCTPP1/UNG 5 GO:0010155 regulation of proton transport 5/719 24/18722 0.001906274044685 0.0208498723637421 PARK7/NDUFA4/COX17/PPIF/PHB2 5 GO:0006298 mismatch repair 6/719 35/18722 0.00196755298815772 0.0212783118101326 PCNA/HMGB1/RPA3/RNASEH2A/RPA2/POLD3 6 GO:0008608 attachment of spindle microtubules to kinetochore 6/719 35/18722 0.00196755298815772 0.0212783118101326 AURKB/CDT1/NUF2/CCNB1/BUB3/ECT2 6 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 6/719 35/18722 0.00196755298815772 0.0212783118101326 PBK/RPL11/PARK7/HSP90AB1/EIF3H/TAF9 6 GO:0072528 pyrimidine-containing compound biosynthetic process 6/719 35/18722 0.00196755298815772 0.0212783118101326 TYMS/DUT/DTYMK/NME1/NME4/UMPS 6 GO:0009144 purine nucleoside triphosphate metabolic process 10/719 88/18722 0.00198711393928451 0.0214296601295389 RAN/ENO1/ALDOA/NME1/IMPDH2/STOML2/NUDT15/PARP1/NME4/ADK 10 GO:0051881 regulation of mitochondrial membrane potential 9/719 74/18722 0.00205286238727944 0.0220768720419716 SOD1/PARK7/PRELID1/UBB/PRDX3/STOML2/PARP1/BNIP3/BAX 9 GO:0031497 chromatin assembly 14/719 151/18722 0.00206643863220734 0.0221324009742698 HMGB2/HMGB1/CENPW/NASP/NPM1/ASF1B/DNAJC9/HELLS/HAT1/ANP32B/NAP1L1/SET/ITGB3BP/MIS18A 14 GO:0045860 positive regulation of protein kinase activity 27/719 386/18722 0.00208350175444153 0.0221324009742698 HMGB1/CKS1B/CALM2/PPIA/NPM1/RPS3/RPLP1/TXN/CLSPN/CALM1/CKS2/CDC6/CCNB1/TPX2/PARK7/HSP90AB1/CD24/HSP90AA1/XRCC6/EZH2/ECT2/PIH1D1/PHB/CCND1/PHB2/HRAS/ITGB1BP1 27 GO:0031398 positive regulation of protein ubiquitination 12/719 119/18722 0.00208801991455863 0.0221324009742698 UBE2C/NPM1/RPS2/UBE2S/CDC20/UBB/RBX1/UBE2L3/UBE2N/CAV1/SKP1/PIN1 12 GO:0009163 nucleoside biosynthetic process 4/719 15/18722 0.00209826658587233 0.0221324009742698 DTYMK/PNP/APRT/ADK 4 GO:0034404 nucleobase-containing small molecule biosynthetic process 4/719 15/18722 0.00209826658587233 0.0221324009742698 DTYMK/PNP/APRT/ADK 4 GO:0042559 pteridine-containing compound biosynthetic process 4/719 15/18722 0.00209826658587233 0.0221324009742698 DHFR/ATIC/PCBD1/PTS 4 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus 4/719 15/18722 0.00209826658587233 0.0221324009742698 RAN/NPM1/RPS15/EIF6 4 GO:0009150 purine ribonucleotide metabolic process 26/719 368/18722 0.00217714042290239 0.0229016137381808 GAPDH/RAN/LDHA/HINT1/ENO1/TPI1/ALDOA/NME1/PKM/PGAM1/PAICS/MPC2/ARL2/IMPDH2/GMPS/STOML2/NUDT8/EIF6/PNP/ATIC/PARP1/NME4/APRT/AK2/SLC25A1/ADK 26 GO:0030261 chromosome condensation 7/719 48/18722 0.00223513948288391 0.0233620987578305 NUSAP1/CDK1/TOP2A/CCNB1/BANF1/SMC2/SMC4 7 GO:0048146 positive regulation of fibroblast proliferation 7/719 48/18722 0.00223513948288391 0.0233620987578305 CCNA2/MIF/CDC6/CCNB1/ANXA2/CDK4/RNASEH2B 7 GO:0009152 purine ribonucleotide biosynthetic process 15/719 169/18722 0.00223912063419207 0.0233620987578305 ENO1/ALDOA/NME1/PAICS/MPC2/IMPDH2/GMPS/STOML2/ATIC/PARP1/NME4/APRT/AK2/SLC25A1/ADK 15 GO:0070670 response to interleukin-4 6/719 36/18722 0.00228558496743291 0.0237183345677 TUBA1B/RPLP0/RPL3/HSP90AB1/IMPDH2/CDK4 6 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 6/719 36/18722 0.00228558496743291 0.0237183345677 RPS3/RPL26/TPT1/MIF/TRIAP1/TAF9 6 GO:0046031 ADP metabolic process 10/719 90/18722 0.00235215524037884 0.0243435421383294 GAPDH/LDHA/ENO1/TPI1/ALDOA/PKM/PGAM1/ARL2/EIF6/AK2 10 GO:0045931 positive regulation of mitotic cell cycle 12/719 121/18722 0.00240322432873852 0.0248053985674084 UBE2C/CDK1/ANAPC11/CDT1/CDC6/CCNB1/RAD51C/APEX1/CCND1/CDK4/PHB2/TFDP1 12 GO:0006090 pyruvate metabolic process 11/719 106/18722 0.00251625325954365 0.0258335334646481 GAPDH/LDHA/ENO1/TPI1/ALDOA/PKM/VDAC1/PGAM1/MPC2/ARL2/EIF6 11 GO:0009185 ribonucleoside diphosphate metabolic process 11/719 106/18722 0.00251625325954365 0.0258335334646481 GAPDH/LDHA/ENO1/TPI1/ALDOA/PKM/PGAM1/ARL2/EIF6/NUDT5/AK2 11 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 13/719 138/18722 0.00255556239948338 0.0261673277606676 UBE2C/NPM1/RPS2/UBE2S/CDC20/UBB/RBX1/UBE2L3/UBE2N/CAV1/SKP1/SAE1/PIN1 13 GO:0006266 DNA ligation 4/719 16/18722 0.00271343149753881 0.0274191896732925 HMGB1/TOP2A/RAD51/XRCC6 4 GO:0019081 viral translation 4/719 16/18722 0.00271343149753881 0.0274191896732925 EIF3F/SSB/EIF3L/MCTS1 4 GO:0099116 tRNA 5'-end processing 4/719 16/18722 0.00271343149753881 0.0274191896732925 POP7/RPP30/SSB/HSD17B10 4 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 4/719 16/18722 0.00271343149753881 0.0274191896732925 RPL26/MIF/TRIAP1/TAF9 4 GO:1905906 regulation of amyloid fibril formation 4/719 16/18722 0.00271343149753881 0.0274191896732925 PFDN2/PFDN4/VBP1/PFDN1 4 GO:0046390 ribose phosphate biosynthetic process 16/719 190/18722 0.00277219963712919 0.027939708384679 ENO1/ALDOA/NME1/PAICS/MPC2/IMPDH2/GMPS/STOML2/ATIC/PARP1/NME4/APRT/AK2/SLC25A1/UMPS/ADK 16 GO:0030490 maturation of SSU-rRNA 7/719 50/18722 0.00283829372160393 0.0285311509874024 RPS16/RPS19/RPS8/RPS14/RPS28/SNU13/LSM6 7 GO:0062197 cellular response to chemical stress 24/719 337/18722 0.00285423765848465 0.0286167056905362 PCNA/CDK1/PPIA/PRDX2/RPS3/PAGE4/PRDX1/TXN/CHCHD2/SOD1/DHFR/PARK7/PRDX5/PRDX3/XRCC6/ROMO1/EZH2/CAV1/AKR1B1/ECT2/APEX1/PPIF/PARP1/BNIP3 24 GO:0048857 neural nucleus development 8/719 64/18722 0.00301604883868685 0.0301604883868685 CALM2/CALM1/YWHAH/DYNLL1/YWHAE/COX6B1/YWHAQ/NDUFS3 8 GO:0007007 inner mitochondrial membrane organization 6/719 38/18722 0.00303588714922015 0.0302802215660559 ROMO1/TIMM8B/TIMM13/NDUFA13/TIMM10/TIMM8A 6 GO:0034766 negative regulation of ion transmembrane transport 11/719 109/18722 0.00313294490982059 0.0311675398005408 CALM2/GSTO1/CALM1/VDAC1/YWHAE/CAV1/YWHAQ/C4orf3/PPIF/SUMO1/ISCU 11 GO:0000245 spliceosomal complex assembly 9/719 79/18722 0.0032277100698073 0.0320167067157419 SNRPD1/SNRPG/SNRPE/SNRPD2/SNRPC/PSIP1/SRSF9/TXNL4A/SF3A3 9 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 10/719 94/18722 0.00324325081016606 0.0320167067157419 CKS1B/CCNA2/CDKN3/CCNB2/CKS2/CDC6/CCNB1/CCNE1/CDKN2A/CCND1 10 GO:0032091 negative regulation of protein binding 10/719 94/18722 0.00324325081016606 0.0320167067157419 AURKB/PARK7/AURKA/PPP1CA/CAV1/BAG2/PIN1/ID1/ITGB1BP1/BAX 10 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 5/719 27/18722 0.00329243171260078 0.0324190846381407 CDK1/CCNB1/RAD51C/CCND1/CDK4 5 GO:0000076 DNA replication checkpoint signaling 4/719 17/18722 0.00344161789109691 0.0336300225399063 CDT1/CLSPN/CDC6/NAE1 4 GO:0009151 purine deoxyribonucleotide metabolic process 4/719 17/18722 0.00344161789109691 0.0336300225399063 DNPH1/NUDT15/PNP/ADK 4 GO:0043968 histone H2A acetylation 4/719 17/18722 0.00344161789109691 0.0336300225399063 MORF4L2/ACTL6A/YEATS4/RUVBL1 4 GO:0016572 histone phosphorylation 6/719 39/18722 0.00347345250012416 0.0338551699379191 CDK1/AURKB/CCNA2/CCNB1/AURKA/VRK1 6 GO:0048145 regulation of fibroblast proliferation 9/719 80/18722 0.00351602782661519 0.0341836038698699 GSTP1/CCNA2/MIF/CDC6/CCNB1/ANXA2/CDK4/RNASEH2B/BAX 9 GO:0043393 regulation of protein binding 16/719 196/18722 0.00376875728263624 0.0365484018593187 RAN/AURKB/RPL11/PARK7/ANXA2/AURKA/HSP90AB1/PPP1CA/PHLDA2/CAV1/BAG2/PCBD1/PIN1/ID1/ITGB1BP1/BAX 16 GO:0006096 glycolytic process 9/719 81/18722 0.00382417990943172 0.0368999815822359 GAPDH/LDHA/ENO1/TPI1/ALDOA/PKM/PGAM1/ARL2/EIF6 9 GO:0048144 fibroblast proliferation 9/719 81/18722 0.00382417990943172 0.0368999815822359 GSTP1/CCNA2/MIF/CDC6/CCNB1/ANXA2/CDK4/RNASEH2B/BAX 9 GO:0034599 cellular response to oxidative stress 21/719 288/18722 0.00386972870941579 0.0371532556889047 PCNA/CDK1/PPIA/PRDX2/RPS3/PAGE4/PRDX1/TXN/CHCHD2/SOD1/DHFR/PARK7/PRDX5/PRDX3/ROMO1/EZH2/ECT2/APEX1/PPIF/PARP1/BNIP3 21 GO:1903311 regulation of mRNA metabolic process 21/719 288/18722 0.00386972870941579 0.0371532556889047 NPM1/HNRNPA1/CARHSP1/CCNB1/YBX1/PRDX6/SRSF3/HNRNPD/SAP18/EXOSC8/C1QBP/SERBP1/MAGOH/RBM8A/NCL/SRSF9/APEX1/POLR2G/RBM3/HNRNPR/HNRNPM 21 GO:0045786 negative regulation of cell cycle 26/719 385/18722 0.00398947293206931 0.0382076387772807 CDK1/GMNN/PTTG1/MAD2L1/NPM1/AURKB/RPL26/CDT1/ZWINT/CLSPN/CDC6/CCNB1/RPA2/AURKAIP1/BUB3/EZH2/TRIAP1/CDKN2A/LCMT1/CCND1/RNASEH2B/PSMG2/NAE1/ANAPC15/NAA10/CDK2AP2 26 GO:0006334 nucleosome assembly 12/719 129/18722 0.00407454592728033 0.0389255628288568 HMGB2/CENPW/NASP/NPM1/ASF1B/DNAJC9/HAT1/ANP32B/NAP1L1/SET/ITGB3BP/MIS18A 12 GO:0006757 ATP generation from ADP 9/719 82/18722 0.00415307892254808 0.0395776085440844 GAPDH/LDHA/ENO1/TPI1/ALDOA/PKM/PGAM1/ARL2/EIF6 9 GO:0044403 biological process involved in symbiotic interaction 21/719 290/18722 0.00419008567857351 0.0398316786728593 CDK1/GAPDH/PPIA/RPSA/SIVA1/NUCKS1/LY6E/CFL1/DYNLT1/PSMC3/HSP90AB1/HSPD1/ROMO1/CAV1/VAMP8/ALYREF/SNX3/PHB/THOC6/PHB2/TCP1 21 GO:0046040 IMP metabolic process 4/719 18/18722 0.00429204460947576 0.0404018869107131 PAICS/PNP/ATIC/APRT 4 GO:0046112 nucleobase biosynthetic process 4/719 18/18722 0.00429204460947576 0.0404018869107131 PAICS/GMPS/APRT/UMPS 4 GO:0048268 clathrin coat assembly 4/719 18/18722 0.00429204460947576 0.0404018869107131 AP2S1/CLTA/CLTB/NSG1 4 GO:0051382 kinetochore assembly 4/719 18/18722 0.00429204460947576 0.0404018869107131 CENPW/CENPN/CENPK/CENPH 4 GO:0006282 regulation of DNA repair 12/719 130/18722 0.00433670760418809 0.0407227421368882 PCNA/HMGB1/RPS3/RAD51/DEK/RAD51AP1/RMI2/RPA2/UBE2N/PARP1/PPP4C/USP1 12 GO:0070301 cellular response to hydrogen peroxide 10/719 98/18722 0.00438416626065654 0.0410682240961744 PCNA/CDK1/RPS3/TXN/PARK7/EZH2/ECT2/APEX1/PPIF/BNIP3 10 GO:0046686 response to cadmium ion 8/719 68/18722 0.00440687493645679 0.0411807487994142 PCNA/MT2A/CDK1/DTYMK/SOD1/CYB5A/NUDT1/SUMO1 8 GO:1901292 nucleoside phosphate catabolic process 9/719 83/18722 0.00450365242259479 0.0419832005496125 DUT/HINT1/DCTPP1/UNG/DNPH1/NUDT8/NUDT15/PNP/NUDT5 9 GO:0007143 female meiotic nuclear division 5/719 29/18722 0.00454664805317143 0.0420783533767067 TOP2A/CCNB2/AURKA/UBB/RAD51C 5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity 5/719 29/18722 0.00454664805317143 0.0420783533767067 CKS1B/CKS2/CDC6/CCNB1/CCND1 5 GO:0070979 protein K11-linked ubiquitination 5/719 29/18722 0.00454664805317143 0.0420783533767067 UBE2C/UBE2T/ANAPC11/UBE2S/UBE2L3 5 GO:0072522 purine-containing compound biosynthetic process 16/719 200/18722 0.00458391087034701 0.0423214792585995 ENO1/ALDOA/NME1/PAICS/MPC2/IMPDH2/GMPS/STOML2/PNP/ATIC/PARP1/NME4/APRT/AK2/SLC25A1/ADK 16 GO:0009145 purine nucleoside triphosphate biosynthetic process 8/719 69/18722 0.00482126216115047 0.0444063620105964 ENO1/ALDOA/NME1/IMPDH2/STOML2/PARP1/NME4/ADK 8 GO:0006414 translational elongation 7/719 55/18722 0.00489029893302268 0.0449347276661988 RPLP1/EEF1A1/EEF1B2/RPLP2/EEF1D/SRP9/EIF5A 7 GO:0009411 response to UV 13/719 149/18722 0.00494254796709269 0.0453066896983497 PCNA/PBK/NPM1/AURKB/RPL26/FEN1/HMGN1/TRIAP1/CCND1/POLD3/PARP1/BAX/USP1 13 GO:0045862 positive regulation of proteolysis 25/719 372/18722 0.0049961170192132 0.0456889561139449 HMGB1/ENO1/RPS3/HSPE1/CDC20/AURKA/PRELID1/PSMC3/ANP32B/RBX1/SUMO2/PDCD5/AURKAIP1/HSPD1/CAV1/PSMD14/PSMC1/BAG2/PSMC5/NDUFA13/CYCS/SUMO1/DDA1/RAD23A/BAX 25 GO:0031503 protein-containing complex localization 17/719 220/18722 0.00501797056350742 0.0457800631978758 RAN/BIRC5/NPM1/RPS15/SRSF3/HNRNPA2B1/HSPB11/ENY2/EIF6/ALYREF/DDX39A/SSB/THOC6/NSG1/HRAS/MZT1/SSNA1 17 GO:1903046 meiotic cell cycle process 16/719 202/18722 0.00504244905268654 0.0458946308577853 PTTG1/TOP2A/RAD51/MND1/RAD51AP1/CCNB2/NUF2/CKS2/CDC20/AURKA/CCNE1/UBB/RAD51C/TUBG1/SMC2/SMC4 16 GO:0006605 protein targeting 22/719 314/18722 0.00506077262414284 0.0459527702899763 RPL11/NACA/UBE2L3/PDCD5/HSPD1/SRP14/SRP9/HSP90AA1/ROMO1/UBL5/TIMM8B/YWHAQ/TIMM13/NDUFA13/SAE1/TIMM10/TIMM8A/HRAS/TOMM40/AP1M2/ITGB1BP1/ZDHHC12 22 GO:0072593 reactive oxygen species metabolic process 18/719 239/18722 0.00516165422779849 0.0467585147694687 PRDX2/GSTP1/PAGE4/PRDX1/SOD1/DHFR/PARK7/VDAC1/PRDX6/PRDX5/HSPD1/PRDX3/DCXR/ROMO1/EIF6/NDUFA13/BNIP3/NDUFS3 18 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 12/719 133/18722 0.00520515291857125 0.0470418749683083 CDC20/AURKA/PSMC3/RBX1/SUMO2/CAV1/PSMC1/BAG2/PSMC5/SUMO1/DDA1/RAD23A 12 GO:0140013 meiotic nuclear division 15/719 185/18722 0.00525847387553116 0.0471070764123995 PTTG1/TOP2A/RAD51/MND1/RAD51AP1/CCNB2/NUF2/CKS2/CDC20/AURKA/CCNE1/UBB/RAD51C/SMC2/SMC4 15 GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process 4/719 19/18722 0.00527354543733615 0.0471070764123995 TYMS/DTYMK/NME1/NME4 4 GO:0034501 protein localization to kinetochore 4/719 19/18722 0.00527354543733615 0.0471070764123995 CDK1/AURKB/CDT1/BUB3 4 GO:1901659 glycosyl compound biosynthetic process 4/719 19/18722 0.00527354543733615 0.0471070764123995 DTYMK/PNP/APRT/ADK 4 GO:1903083 protein localization to condensed chromosome 4/719 19/18722 0.00527354543733615 0.0471070764123995 CDK1/AURKB/CDT1/BUB3 4 GO:0006099 tricarboxylic acid cycle 5/719 30/18722 0.00528656665965599 0.0471140778696194 IDH2/MDH1/MDH2/FH/SUCLG1 5 GO:0051225 spindle assembly 11/719 117/18722 0.00538471243796845 0.0478779281435994 TUBB/PRC1/RPS3/AURKB/CCNB2/CDC20/TPX2/AURKA/HAUS1/MZT1/SMC3 11 GO:0009113 purine nucleobase biosynthetic process 3/719 10/18722 0.00552846375618901 0.0488178565626782 PAICS/GMPS/APRT 3 GO:0033314 mitotic DNA replication checkpoint signaling 3/719 10/18722 0.00552846375618901 0.0488178565626782 CLSPN/CDC6/NAE1 3 GO:0043101 purine-containing compound salvage 3/719 10/18722 0.00552846375618901 0.0488178565626782 PNP/APRT/ADK 3 GO:0090150 establishment of protein localization to membrane 19/719 260/18722 0.00569389211060766 0.0501278415596886 CALM1/NACA/KRT18/CD24/PDCD5/SRP14/SRP9/HSP90AA1/ROMO1/TIMM8B/TIMM13/NDUFA13/TIMM10/TIMM8A/NSG1/HRAS/ITGB1BP1/BAX/ZDHHC12 19 GO:1904591 positive regulation of protein import 6/719 43/18722 0.00570285574107626 0.0501278415596886 CDK1/RAN/HSP90AB1/PDCD5/NUTF2/ECT2 6 GO:1904063 negative regulation of cation transmembrane transport 10/719 102/18722 0.00581996000938489 0.0510406515629427 CALM2/GSTO1/CALM1/VDAC1/YWHAE/CAV1/C4orf3/PPIF/SUMO1/ISCU 10 GO:0017038 protein import 16/719 206/18722 0.00607159447558102 0.0531264516613339 CDK1/RAN/RPL23/KPNA2/HSP90AB1/PDCD5/HSPD1/HSP90AA1/ROMO1/NUTF2/ECT2/NXT1/PHB2/SUMO1/TOMM40/CSE1L 16 GO:0007338 single fertilization 13/719 153/18722 0.00616125317637387 0.0537887182064385 CDK1/ALDOA/PARK7/SLIRP/CCT5/SNU13/CCT2/VDAC2/CCT8/CCT3/CCT7/CCT4/TCP1 13 GO:0009135 purine nucleoside diphosphate metabolic process 10/719 103/18722 0.00623053660134673 0.0541480043232165 GAPDH/LDHA/ENO1/TPI1/ALDOA/PKM/PGAM1/ARL2/EIF6/AK2 10 GO:0009179 purine ribonucleoside diphosphate metabolic process 10/719 103/18722 0.00623053660134673 0.0541480043232165 GAPDH/LDHA/ENO1/TPI1/ALDOA/PKM/PGAM1/ARL2/EIF6/AK2 10 GO:0071479 cellular response to ionizing radiation 8/719 72/18722 0.00624484907720732 0.054150155286595 RAD51/RPL26/RAD51AP1/NUCKS1/EEF1D/XRCC6/ECT2/HRAS 8 GO:0032986 protein-DNA complex disassembly 4/719 20/18722 0.00639452035091786 0.0551993348677887 HMGA1/RPL23/SET/SUPT16H 4 GO:0048025 negative regulation of mRNA splicing, via spliceosome 4/719 20/18722 0.00639452035091786 0.0551993348677887 NPM1/SAP18/C1QBP/SRSF9 4 GO:0042743 hydrogen peroxide metabolic process 7/719 58/18722 0.00656556556869579 0.0564822412287664 PRDX2/PRDX1/SOD1/PARK7/PRDX6/PRDX5/PRDX3 7 GO:0050684 regulation of mRNA processing 12/719 137/18722 0.00657247897934736 0.0564822412287664 NPM1/HNRNPA1/CCNB1/PRDX6/SRSF3/SAP18/C1QBP/MAGOH/RBM8A/NCL/SRSF9/RBM3 12 GO:0009166 nucleotide catabolic process 8/719 73/18722 0.00678386534932367 0.0581690013249357 DUT/HINT1/DCTPP1/UNG/DNPH1/NUDT8/NUDT15/PNP 8 GO:1903364 positive regulation of cellular protein catabolic process 13/719 155/18722 0.00685443698013096 0.0586435163855649 CDC20/AURKA/PSMC3/RBX1/SUMO2/HSP90AA1/CAV1/PSMC1/BAG2/PSMC5/SUMO1/DDA1/RAD23A 13 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 16/719 209/18722 0.0069498627015172 0.0593280962324639 HMGB1/BIRC5/RPS3/HSPE1/PARK7/PRDX5/ANP32B/BCL2L12/PDCD5/HSPD1/PRDX3/TRIAP1/PIH1D1/NDUFA13/CYCS/BAX 16 GO:0042744 hydrogen peroxide catabolic process 5/719 32/18722 0.00701448324355422 0.0596174340856309 PRDX2/PRDX1/PRDX6/PRDX5/PRDX3 5 GO:0006164 purine nucleotide biosynthetic process 15/719 191/18722 0.00701472665994566 0.0596174340856309 ENO1/ALDOA/NME1/PAICS/MPC2/IMPDH2/GMPS/STOML2/ATIC/PARP1/NME4/APRT/AK2/SLC25A1/ADK 15 GO:0001836 release of cytochrome c from mitochondria 7/719 59/18722 0.00720889714971461 0.060636000864078 GGCT/PRELID1/PDCD5/TRIAP1/PPIF/BNIP3/BAX 7 GO:0006635 fatty acid beta-oxidation 8/719 74/18722 0.00735732025381387 0.060636000864078 ACAT2/ECHS1/ETFB/ECH1/ECI1/HADH/ETFA/HSD17B10 8 GO:0010822 positive regulation of mitochondrion organization 8/719 74/18722 0.00735732025381387 0.060636000864078 SLC25A5/PARK7/VDAC1/AURKA/PDCD5/PPIF/BNIP3/BAX 8 GO:0001731 formation of translation preinitiation complex 3/719 11/18722 0.00738656737798769 0.060636000864078 RPL13A/EIF2S2/MCTS1 3 GO:0001765 membrane raft assembly 3/719 11/18722 0.00738656737798769 0.060636000864078 S100A10/ANXA2/CAV1 3 GO:0006183 GTP biosynthetic process 3/719 11/18722 0.00738656737798769 0.060636000864078 NME1/IMPDH2/NME4 3 GO:0006188 IMP biosynthetic process 3/719 11/18722 0.00738656737798769 0.060636000864078 PAICS/ATIC/APRT 3 GO:0007144 female meiosis I 3/719 11/18722 0.00738656737798769 0.060636000864078 CCNB2/AURKA/UBB 3 GO:0009120 deoxyribonucleoside metabolic process 3/719 11/18722 0.00738656737798769 0.060636000864078 TK1/DTYMK/PNP 3 GO:0009155 purine deoxyribonucleotide catabolic process 3/719 11/18722 0.00738656737798769 0.060636000864078 DNPH1/NUDT15/PNP 3 GO:0042451 purine nucleoside biosynthetic process 3/719 11/18722 0.00738656737798769 0.060636000864078 PNP/APRT/ADK 3 GO:0042455 ribonucleoside biosynthetic process 3/719 11/18722 0.00738656737798769 0.060636000864078 PNP/APRT/ADK 3 GO:0046129 purine ribonucleoside biosynthetic process 3/719 11/18722 0.00738656737798769 0.060636000864078 PNP/APRT/ADK 3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 3/719 11/18722 0.00738656737798769 0.060636000864078 CALM2/GSTO1/CALM1 3 GO:0075522 IRES-dependent viral translational initiation 3/719 11/18722 0.00738656737798769 0.060636000864078 EIF3F/SSB/MCTS1 3 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction 3/719 11/18722 0.00738656737798769 0.060636000864078 CALM2/CALM1/CAV1 3 GO:0046822 regulation of nucleocytoplasmic transport 10/719 106/18722 0.00759845795685888 0.0622408161109421 CDK1/RAN/TXN/PARK7/ANP32B/HSP90AB1/YWHAE/NUTF2/ECT2/SUMO1 10 GO:0030901 midbrain development 9/719 90/18722 0.00764511169962627 0.0622408161109421 CALM2/UQCRQ/CALM1/YWHAH/DYNLL1/YWHAE/COX6B1/YWHAQ/NDUFS3 9 GO:0034644 cellular response to UV 9/719 90/18722 0.00764511169962627 0.0622408161109421 PCNA/PBK/NPM1/AURKB/RPL26/TRIAP1/POLD3/PARP1/BAX 9 GO:0031145 anaphase-promoting complex-dependent catabolic process 4/719 21/18722 0.00766289528223027 0.0622408161109421 UBE2C/ANAPC11/UBE2S/CDC20 4 GO:0034471 ncRNA 5'-end processing 4/719 21/18722 0.00766289528223027 0.0622408161109421 POP7/RPP30/SSB/HSD17B10 4 GO:0051348 negative regulation of transferase activity 19/719 268/18722 0.00779402402133507 0.0631726157518737 PPIA/MAD2L1/GSTP1/NPM1/RPS15/RPL11/RPS7/RPL37/RPL5/RPS20/PHPT1/PARK7/RPL23/PRDX3/PKIB/CAV1/CDKN2A/BAG2/ITGB1BP1 19 GO:0006289 nucleotide-excision repair 7/719 60/18722 0.00789773690574615 0.0638787543847115 HMGB1/RPA3/RPA2/HMGN1/POLR2I/POLD3/RAD23A 7 GO:0043627 response to estrogen 8/719 75/18722 0.00796653966993809 0.0643001629544269 LDHA/DTYMK/KRT19/COMT/CD24/HSPD1/CAV1/CCND1 8 GO:0042558 pteridine-containing compound metabolic process 5/719 33/18722 0.00801120921479792 0.0645254298681423 TYMS/DHFR/ATIC/PCBD1/PTS 5 GO:0008637 apoptotic mitochondrial changes 10/719 107/18722 0.00810244211146495 0.0651240127956995 GGCT/SLC25A5/PRELID1/PDCD5/HSPD1/TRIAP1/VDAC2/PPIF/BNIP3/BAX 10 GO:0007595 lactation 6/719 47/18722 0.00882954231551752 0.0706730517978014 NME1/CAV1/CCND1/APRT/SLC29A1/UMPS 6 GO:1903170 negative regulation of calcium ion transmembrane transport 6/719 47/18722 0.00882954231551752 0.0706730517978014 CALM2/GSTO1/CALM1/VDAC1/YWHAE/C4orf3 6 GO:0090316 positive regulation of intracellular protein transport 13/719 160/18722 0.00885960738357357 0.0707665734994984 CDK1/RAN/ANP32B/HSP90AB1/UBE2L3/YWHAE/PDCD5/UBL5/NUTF2/ECT2/SAE1/HRAS/ITGB1BP1 13 GO:2001235 positive regulation of apoptotic signaling pathway 11/719 126/18722 0.00927071667931305 0.0738970170090171 RPS3/RPL26/RPL11/RPS7/SOD1/PARK7/UBB/PPP1CA/EIF5A/CAV1/BAX 11 GO:0046173 polyol biosynthetic process 7/719 62/18722 0.00941924752272909 0.0747713463144474 DHFR/PGP/IMPA2/AKR1B1/ISYNA1/PCBD1/PTS 7 GO:0046824 positive regulation of nucleocytoplasmic transport 7/719 62/18722 0.00941924752272909 0.0747713463144474 CDK1/RAN/ANP32B/HSP90AB1/YWHAE/NUTF2/ECT2 7 GO:0043471 regulation of cellular carbohydrate catabolic process 3/719 12/18722 0.00957067964360056 0.0755063865325044 HMGB1/PGAM1/PPP1CA 3 GO:1990034 calcium ion export across plasma membrane 3/719 12/18722 0.00957067964360056 0.0755063865325044 CALM2/CALM1/YWHAE 3 GO:2000105 positive regulation of DNA-dependent DNA replication 3/719 12/18722 0.00957067964360056 0.0755063865325044 CDT1/SSBP1/STOML2 3 GO:0010569 regulation of double-strand break repair via homologous recombination 6/719 48/18722 0.00977159986303662 0.0766856702231573 RAD51/RAD51AP1/RMI2/RPA2/PARP1/PPP4C 6 GO:0090199 regulation of release of cytochrome c from mitochondria 6/719 48/18722 0.00977159986303662 0.0766856702231573 PRELID1/PDCD5/TRIAP1/PPIF/BNIP3/BAX 6 GO:0051100 negative regulation of binding 13/719 162/18722 0.00977991274794032 0.0766856702231573 AURKB/PARK7/AURKA/PPP1CA/CAV1/BAG2/C4orf3/MDFI/SUMO1/PIN1/ID1/ITGB1BP1/BAX 13 GO:0016032 viral process 26/719 415/18722 0.0102350002980439 0.0800889680010706 CDK1/RAN/PPIA/TOP2A/RPSA/DEK/SIVA1/NUCKS1/LY6E/CFL1/KPNA2/DYNLT1/PSMC3/BANF1/EIF3F/HSP90AB1/CAV1/VAMP8/SNX3/PHB/SSB/PPIH/EIF3L/PHB2/RAD23A/MCTS1 26 GO:1904589 regulation of protein import 7/719 63/18722 0.0102555483700072 0.0800889680010706 CDK1/RAN/HSP90AB1/PDCD5/NUTF2/ECT2/SUMO1 7 GO:0000966 RNA 5'-end processing 4/719 23/18722 0.0106709904975557 0.0828292609185275 POP7/RPP30/SSB/HSD17B10 4 GO:0019430 removal of superoxide radicals 4/719 23/18722 0.0106709904975557 0.0828292609185275 PRDX2/PRDX1/SOD1/DHFR 4 GO:0051457 maintenance of protein location in nucleus 4/719 23/18722 0.0106709904975557 0.0828292609185275 TXN/PARK7/ARL2/SKP1 4 GO:0018198 peptidyl-cysteine modification 6/719 49/18722 0.0107830474288943 0.083362916869966 GAPDH/TXN/PARK7/PRDX3/ADH5/ZDHHC12 6 GO:1901799 negative regulation of proteasomal protein catabolic process 6/719 49/18722 0.0107830474288943 0.083362916869966 PBK/RPL11/PARK7/HSP90AB1/EIF3H/TAF9 6 GO:0007127 meiosis I 11/719 129/18722 0.0109592522249441 0.0845553528377447 PTTG1/TOP2A/RAD51/MND1/RAD51AP1/CCNB2/CKS2/AURKA/CCNE1/UBB/RAD51C 11 GO:0006749 glutathione metabolic process 7/719 64/18722 0.0111446097159588 0.085813494812883 GSTO1/GSTP1/SOD1/PARK7/GPX4/GLO1/ETHE1 7 GO:0001889 liver development 12/719 147/18722 0.011241179768387 0.0863843155854092 TYMS/PCNA/RPS16/RPS15/RPL19/KRT18/AURKA/HNRNPD/CSNK2B/EZH2/CCND1/HRAS 12 GO:0043648 dicarboxylic acid metabolic process 9/719 96/18722 0.0114758860152972 0.0880122732248887 DHFR/IDH2/MDH1/MDH2/QPRT/ATIC/FH/GRHPR/NIT2 9 GO:0010212 response to ionizing radiation 12/719 148/18722 0.0118209572570948 0.0904784998803481 RAD51/RPL26/RAD51AP1/RRM1/NUCKS1/EEF1D/XRCC6/ECT2/CCND1/PARP1/HRAS/BAX 12 GO:0044843 cell cycle G1/S phase transition 17/719 241/18722 0.0119741296539562 0.0914569060516962 NASP/RPS6/RPL26/CCNA2/CDKN3/CDC6/CCNE1/RPA2/EZH2/TRIAP1/CDKN2A/APEX1/CCND1/CDK4/PHB2/TFDP1/CDK2AP2 17 GO:0001682 tRNA 5'-leader removal 3/719 13/18722 0.0120913156312502 0.0914569060516962 POP7/RPP30/SSB 3 GO:0009143 nucleoside triphosphate catabolic process 3/719 13/18722 0.0120913156312502 0.0914569060516962 DUT/DCTPP1/NUDT15 3 GO:0010917 negative regulation of mitochondrial membrane potential 3/719 13/18722 0.0120913156312502 0.0914569060516962 PRELID1/BNIP3/BAX 3 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 3/719 13/18722 0.0120913156312502 0.0914569060516962 CALM2/GSTO1/CALM1 3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore 3/719 13/18722 0.0120913156312502 0.0914569060516962 AURKB/CCNB1/ECT2 3 GO:0051321 meiotic cell cycle 18/719 261/18722 0.012292382770648 0.0927954385627351 PTTG1/TOP2A/RAD51/MND1/RAD51AP1/CCNB2/NUF2/CKS2/CDC20/AURKA/CCNE1/UBB/RAD51C/TUBG1/BUB3/SMC2/SMC4/SMC3 18 GO:1901984 negative regulation of protein acetylation 4/719 24/18722 0.0124239337881299 0.0936049805954993 PARK7/SET/HINT2/PIH1D1 4 GO:0000154 rRNA modification 5/719 37/18722 0.0129795162048589 0.0975998777123178 TRMT112/NHP2/METTL5/FBL/NOP10 5 GO:0061008 hepaticobiliary system development 12/719 150/18722 0.0130491960768414 0.0979325631497843 TYMS/PCNA/RPS16/RPS15/RPL19/KRT18/AURKA/HNRNPD/CSNK2B/EZH2/CCND1/HRAS 12 GO:0009205 purine ribonucleoside triphosphate metabolic process 8/719 82/18722 0.0133439228618883 0.0999496167670619 RAN/ENO1/ALDOA/NME1/IMPDH2/STOML2/PARP1/NME4 8 GO:0072523 purine-containing compound catabolic process 6/719 52/18722 0.0142588198086634 0.106250302093352 HINT1/DNPH1/NUDT1/NUDT8/NUDT15/PNP 6 GO:0032147 activation of protein kinase activity 11/719 134/18722 0.0142842842643262 0.106250302093352 HMGB1/PPIA/RPLP1/TXN/CLSPN/TPX2/PARK7/ECT2/PHB/PHB2/ITGB1BP1 11 GO:0046039 GTP metabolic process 4/719 25/18722 0.0143506901528684 0.106250302093352 RAN/NME1/IMPDH2/NME4 4 GO:0071450 cellular response to oxygen radical 4/719 25/18722 0.0143506901528684 0.106250302093352 PRDX2/PRDX1/SOD1/DHFR 4 GO:0071451 cellular response to superoxide 4/719 25/18722 0.0143506901528684 0.106250302093352 PRDX2/PRDX1/SOD1/DHFR 4 GO:0071459 protein localization to chromosome, centromeric region 4/719 25/18722 0.0143506901528684 0.106250302093352 CDK1/AURKB/CDT1/BUB3 4 GO:0009062 fatty acid catabolic process 9/719 100/18722 0.0147279010218133 0.108439812303271 ACAT2/ECHS1/ETFB/ECH1/ECI1/NUDT8/HADH/ETFA/HSD17B10 9 GO:0000212 meiotic spindle organization 3/719 14/18722 0.0149562442423472 0.108439812303271 CCNB2/AURKA/TUBG1 3 GO:0006287 base-excision repair, gap-filling 3/719 14/18722 0.0149562442423472 0.108439812303271 PCNA/FEN1/APEX1 3 GO:0007100 mitotic centrosome separation 3/719 14/18722 0.0149562442423472 0.108439812303271 RANBP1/AURKA/NSFL1C 3 GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process 3/719 14/18722 0.0149562442423472 0.108439812303271 TYMS/DUT/UMPS 3 GO:0042921 glucocorticoid receptor signaling pathway 3/719 14/18722 0.0149562442423472 0.108439812303271 YWHAH/PTGES3/PHB 3 GO:0045837 negative regulation of membrane potential 3/719 14/18722 0.0149562442423472 0.108439812303271 PRELID1/BNIP3/BAX 3 GO:1901857 positive regulation of cellular respiration 3/719 14/18722 0.0149562442423472 0.108439812303271 PARK7/PRELID1/ISCU 3 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 3/719 14/18722 0.0149562442423472 0.108439812303271 MIF/TRIAP1/TAF9 3 GO:1902969 mitotic DNA replication 3/719 14/18722 0.0149562442423472 0.108439812303271 RAD51/MCM4/MCM3 3 GO:2001140 positive regulation of phospholipid transport 3/719 14/18722 0.0149562442423472 0.108439812303271 DBI/PRELID1/TRIAP1 3 GO:0061982 meiosis I cell cycle process 11/719 135/18722 0.0150318439884886 0.108783081495641 PTTG1/TOP2A/RAD51/MND1/RAD51AP1/CCNB2/CKS2/AURKA/CCNE1/UBB/RAD51C 11 GO:0009566 fertilization 14/719 190/18722 0.015143960035494 0.109388829524675 CDK1/ALDOA/PARK7/SLIRP/CCT5/SNU13/CCT2/VDAC2/CCT8/CCT3/CCT7/CCT4/TCP1/BAX 14 GO:0009206 purine ribonucleoside triphosphate biosynthetic process 7/719 68/18722 0.0152635874216195 0.11004646362029 ENO1/ALDOA/NME1/IMPDH2/STOML2/PARP1/NME4 7 GO:0033157 regulation of intracellular protein transport 16/719 229/18722 0.0157276851049479 0.113180537671121 CDK1/RAN/TXN/PARK7/ANP32B/HSP90AB1/UBE2L3/YWHAE/PDCD5/UBL5/NUTF2/ECT2/SAE1/SUMO1/HRAS/ITGB1BP1 16 GO:0016052 carbohydrate catabolic process 12/719 154/18722 0.0157958472994548 0.11345897780392 HMGB1/GAPDH/LDHA/ENO1/TPI1/ALDOA/PKM/PGAM1/ARL2/PPP1CA/EIF6/NUDT5 12 GO:0000910 cytokinesis 13/719 173/18722 0.0162465187548609 0.11647876574714 STMN1/NUSAP1/CALM2/PRC1/AURKB/CALM1/CDC6/AURKA/CKAP2/ECT2/RHOC/PIN1/DCTN3 13 GO:0044774 mitotic DNA integrity checkpoint signaling 8/719 85/18722 0.0163167732275284 0.116680216938706 CDK1/RPL26/CLSPN/CDC6/RPA2/TRIAP1/CCND1/NAE1 8 GO:0034605 cellular response to heat 7/719 69/18722 0.0164425596284466 0.116680216938706 HSP90AB1/YWHAE/HSBP1/HSPD1/HSP90AA1/RBBP7/SUMO1 7 GO:0016226 iron-sulfur cluster assembly 4/719 26/18722 0.0164564565708357 0.116680216938706 NFU1/GLRX3/NUBP2/ISCU 4 GO:0031163 metallo-sulfur cluster assembly 4/719 26/18722 0.0164564565708357 0.116680216938706 NFU1/GLRX3/NUBP2/ISCU 4 GO:0042278 purine nucleoside metabolic process 4/719 26/18722 0.0164564565708357 0.116680216938706 NUDT1/PNP/APRT/ADK 4 GO:0043094 cellular metabolic compound salvage 4/719 26/18722 0.0164564565708357 0.116680216938706 ADI1/PNP/APRT/ADK 4 GO:0019395 fatty acid oxidation 9/719 103/18722 0.0175790975316699 0.12441089245759 ACAT2/ECHS1/ETFB/ECH1/ECI1/ADH5/HADH/ETFA/HSD17B10 9 GO:1901020 negative regulation of calcium ion transmembrane transporter activity 5/719 40/18722 0.0178412699190579 0.124701147642414 CALM2/GSTO1/CALM1/YWHAE/C4orf3 5 GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 5/719 40/18722 0.0178412699190579 0.124701147642414 SLC25A5/VDAC2/PPIF/BNIP3/BAX 5 GO:1901654 response to ketone 14/719 194/18722 0.017841808416521 0.124701147642414 TYMS/PCNA/NASP/RPL27/CALM1/NME1/PARK7/HNRNPD/CSNK2B/CAV1/AKR1B1/CCND1/CDK4/PARP1 14 GO:0002262 myeloid cell homeostasis 12/719 157/18722 0.0181270656227895 0.124701147642414 HMGB2/HMGB1/SLC25A5/RPS6/RPS19/RPS14/RPS24/PRDX1/RPS17/SOD1/PRMT1/BAX 12 GO:2000377 regulation of reactive oxygen species metabolic process 12/719 157/18722 0.0181270656227895 0.124701147642414 PRDX2/GSTP1/PAGE4/SOD1/DHFR/PARK7/VDAC1/HSPD1/DCXR/ROMO1/EIF6/BNIP3 12 GO:0000722 telomere maintenance via recombination 3/719 15/18722 0.018170738656466 0.124701147642414 RAD51/RAD51C/TPRKB 3 GO:0006089 lactate metabolic process 3/719 15/18722 0.018170738656466 0.124701147642414 LDHA/PARK7/PNKD 3 GO:0031958 corticosteroid receptor signaling pathway 3/719 15/18722 0.018170738656466 0.124701147642414 YWHAH/PTGES3/PHB 3 GO:0033599 regulation of mammary gland epithelial cell proliferation 3/719 15/18722 0.018170738656466 0.124701147642414 CCND1/PHB2/BAX 3 GO:0048569 post-embryonic animal organ development 3/719 15/18722 0.018170738656466 0.124701147642414 LDHA/HMGN1/BAX 3 GO:0051284 positive regulation of sequestering of calcium ion 3/719 15/18722 0.018170738656466 0.124701147642414 CALM2/GSTO1/CALM1 3 GO:0051290 protein heterotetramerization 3/719 15/18722 0.018170738656466 0.124701147642414 RRM2/RRM1/KRT10 3 GO:0051299 centrosome separation 3/719 15/18722 0.018170738656466 0.124701147642414 RANBP1/AURKA/NSFL1C 3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore 3/719 15/18722 0.018170738656466 0.124701147642414 AURKB/CDT1/NUF2 3 GO:0070131 positive regulation of mitochondrial translation 3/719 15/18722 0.018170738656466 0.124701147642414 UQCC2/C1QBP/COA3 3 GO:1901660 calcium ion export 3/719 15/18722 0.018170738656466 0.124701147642414 CALM2/CALM1/YWHAE 3 GO:2001138 regulation of phospholipid transport 3/719 15/18722 0.018170738656466 0.124701147642414 DBI/PRELID1/TRIAP1 3 GO:0000082 G1/S transition of mitotic cell cycle 15/719 214/18722 0.0184708289785862 0.126535038376436 NASP/RPS6/RPL26/CDKN3/CDC6/CCNE1/RPA2/EZH2/TRIAP1/CDKN2A/APEX1/CCND1/CDK4/TFDP1/CDK2AP2 15 GO:1903578 regulation of ATP metabolic process 8/719 87/18722 0.0185469041659276 0.126830516942844 ENO1/PGAM1/UQCC2/ARL2/COX7A2/EIF6/PPIF/PARP1 8 GO:0009651 response to salt stress 4/719 27/18722 0.0187458521983549 0.127963707382387 HSP90AB1/XRCC6/AKR1B1/BAX 4 GO:2000116 regulation of cysteine-type endopeptidase activity 16/719 235/18722 0.0195805108360584 0.133424719856327 HMGB1/BIRC5/RPS3/HSPE1/PARK7/PRDX5/ANP32B/BCL2L12/PDCD5/HSPD1/PRDX3/TRIAP1/PIH1D1/NDUFA13/CYCS/BAX 16 GO:0042307 positive regulation of protein import into nucleus 5/719 41/18722 0.0196960464693151 0.133974874393751 CDK1/RAN/HSP90AB1/NUTF2/ECT2 5 GO:0051170 import into nucleus 12/719 159/18722 0.0198185534027513 0.134570424339669 CDK1/RAN/HNRNPA1/RPL23/KPNA2/HSP90AB1/NUTF2/ECT2/NXT1/PHB2/SUMO1/CSE1L 12 GO:0010332 response to gamma radiation 6/719 56/18722 0.020011367254633 0.135640429454819 RAD51/RPL26/XRCC6/PARP1/HRAS/BAX 6 GO:0031570 DNA integrity checkpoint signaling 10/719 123/18722 0.0201564850801421 0.136383950015021 CDK1/RPL26/CDT1/CLSPN/CDC6/RPA2/TRIAP1/CCND1/RNASEH2B/NAE1 10 GO:0009199 ribonucleoside triphosphate metabolic process 8/719 89/18722 0.0209869352808685 0.141753861107621 RAN/ENO1/ALDOA/NME1/IMPDH2/STOML2/PARP1/NME4 8 GO:0016570 histone modification 27/719 463/18722 0.0210829858717237 0.142153232234915 CDK1/AURKB/CCNA2/CCNB1/PARK7/TRMT112/AURKA/VRK1/HAT1/UBE2N/SET/ENY2/MORF4L2/EZH2/SKP1/PIH1D1/DPY30/ACTL6A/PHB/FBL/PRMT1/NTMT1/TAF9/DNMT1/YEATS4/RUVBL1/POLE3 27 GO:0000303 response to superoxide 4/719 28/18722 0.0212229182617752 0.14259726929814 PRDX2/PRDX1/SOD1/DHFR 4 GO:0090200 positive regulation of release of cytochrome c from mitochondria 4/719 28/18722 0.0212229182617752 0.14259726929814 PDCD5/PPIF/BNIP3/BAX 4 GO:0006206 pyrimidine nucleobase metabolic process 3/719 16/18722 0.0217378095392953 0.144793368038558 TYMS/RRM1/UMPS 3 GO:0010649 regulation of cell communication by electrical coupling 3/719 16/18722 0.0217378095392953 0.144793368038558 CALM2/CALM1/CAV1 3 GO:0017014 protein nitrosylation 3/719 16/18722 0.0217378095392953 0.144793368038558 GAPDH/TXN/ADH5 3 GO:0018119 peptidyl-cysteine S-nitrosylation 3/719 16/18722 0.0217378095392953 0.144793368038558 GAPDH/TXN/ADH5 3 GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 3/719 16/18722 0.0217378095392953 0.144793368038558 PARK7/PIH1D1/BAX 3 GO:0034763 negative regulation of transmembrane transport 11/719 143/18722 0.0221125251992128 0.147034925763332 CALM2/GSTO1/CALM1/VDAC1/YWHAE/CAV1/YWHAQ/C4orf3/PPIF/SUMO1/ISCU 11 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 8/719 90/18722 0.0222885766058678 0.147695387147317 CDC20/AURKA/RBX1/SUMO2/CAV1/SUMO1/DDA1/RAD23A 8 GO:0035304 regulation of protein dephosphorylation 8/719 90/18722 0.0222885766058678 0.147695387147317 CALM2/PPIA/CALM1/HSP90AB1/YWHAE/CSNK2B/PIN1/ENSA 8 GO:0034440 lipid oxidation 9/719 108/18722 0.02319353871422 0.153354586583877 ACAT2/ECHS1/ETFB/ECH1/ECI1/ADH5/HADH/ETFA/HSD17B10 9 GO:0033674 positive regulation of kinase activity 27/719 467/18722 0.0232222659684156 0.153354586583877 HMGB1/CKS1B/CALM2/PPIA/NPM1/RPS3/RPLP1/TXN/CLSPN/CALM1/CKS2/CDC6/CCNB1/TPX2/PARK7/HSP90AB1/CD24/HSP90AA1/XRCC6/EZH2/ECT2/PIH1D1/PHB/CCND1/PHB2/HRAS/ITGB1BP1 27 GO:0009201 ribonucleoside triphosphate biosynthetic process 7/719 74/18722 0.0233133928266846 0.153692743806055 ENO1/ALDOA/NME1/IMPDH2/STOML2/PARP1/NME4 7 GO:1902808 positive regulation of cell cycle G1/S phase transition 6/719 58/18722 0.023405875005071 0.154038664563287 CDC6/EZH2/APEX1/CCND1/PHB2/TFDP1 6 GO:0035794 positive regulation of mitochondrial membrane permeability 5/719 43/18722 0.0237740912182254 0.155373002966781 SLC25A5/VDAC2/PPIF/BNIP3/BAX 5 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 5/719 43/18722 0.0237740912182254 0.155373002966781 RPL26/MIF/TRIAP1/PHLDA3/TAF9 5 GO:0000305 response to oxygen radical 4/719 29/18722 0.0238911214951518 0.155373002966781 PRDX2/PRDX1/SOD1/DHFR 4 GO:0010458 exit from mitosis 4/719 29/18722 0.0238911214951518 0.155373002966781 UBE2C/RPL24/UBE2S/PHB2 4 GO:0050686 negative regulation of mRNA processing 4/719 29/18722 0.0238911214951518 0.155373002966781 NPM1/SAP18/C1QBP/SRSF9 4 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 4/719 29/18722 0.0238911214951518 0.155373002966781 PPIA/SOD1/PARK7/PARP1 4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 4/719 29/18722 0.0238911214951518 0.155373002966781 TPT1/MIF/TRIAP1/TAF9 4 GO:0032388 positive regulation of intracellular transport 14/719 202/18722 0.0243153960047561 0.157865555848754 CDK1/RAN/ANXA2/ANP32B/HSP90AB1/UBE2L3/YWHAE/PDCD5/UBL5/NUTF2/ECT2/SAE1/HRAS/ITGB1BP1 14 GO:0032465 regulation of cytokinesis 8/719 92/18722 0.0250606984942658 0.162430453203574 CALM2/PRC1/AURKB/CALM1/CDC6/AURKA/ECT2/PIN1 8 GO:0051701 biological process involved in interaction with host 14/719 203/18722 0.0252333894945773 0.162767263463337 CDK1/PPIA/RPSA/SIVA1/LY6E/DYNLT1/CAV1/VAMP8/ALYREF/SNX3/PHB/THOC6/PHB2/TCP1 14 GO:0006406 mRNA export from nucleus 6/719 59/18722 0.0252394951396396 0.162767263463337 SRSF3/HNRNPA2B1/ENY2/ALYREF/DDX39A/THOC6 6 GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus 6/719 59/18722 0.0252394951396396 0.162767263463337 SRSF3/HNRNPA2B1/ENY2/ALYREF/DDX39A/THOC6 6 GO:0007076 mitotic chromosome condensation 3/719 17/18722 0.0256584220353378 0.164367595401082 NUSAP1/SMC2/SMC4 3 GO:0042053 regulation of dopamine metabolic process 3/719 17/18722 0.0256584220353378 0.164367595401082 PARK7/COMT/PNKD 3 GO:0042069 regulation of catecholamine metabolic process 3/719 17/18722 0.0256584220353378 0.164367595401082 PARK7/COMT/PNKD 3 GO:1904355 positive regulation of telomere capping 3/719 17/18722 0.0256584220353378 0.164367595401082 AURKB/HNRNPD/PKIB 3 GO:0009408 response to heat 9/719 110/18722 0.0257626355434328 0.16476104126614 SOD1/HSP90AB1/YWHAE/PSIP1/HSBP1/HSPD1/HSP90AA1/RBBP7/SUMO1 9 GO:0007589 body fluid secretion 8/719 93/18722 0.0265333238422144 0.169408452392248 NME1/ANXA2/CAV1/VAMP8/CCND1/APRT/SLC29A1/UMPS 8 GO:0019674 NAD metabolic process 4/719 30/18722 0.0267533607006127 0.169408616278551 LDHA/ENO1/MDH1/QPRT 4 GO:0031571 mitotic G1 DNA damage checkpoint signaling 4/719 30/18722 0.0267533607006127 0.169408616278551 RPL26/RPA2/TRIAP1/CCND1 4 GO:0044788 modulation by host of viral process 4/719 30/18722 0.0267533607006127 0.169408616278551 NUCKS1/CFL1/PSMC3/PHB 4 GO:0045070 positive regulation of viral genome replication 4/719 30/18722 0.0267533607006127 0.169408616278551 PPIA/TOP2A/PPIH/RAD23A 4 GO:0046825 regulation of protein export from nucleus 4/719 30/18722 0.0267533607006127 0.169408616278551 TXN/PARK7/ANP32B/YWHAE 4 GO:0035825 homologous recombination 6/719 60/18722 0.0271663571656278 0.171459795225683 TOP2A/RAD51/MND1/RAD51AP1/NUCKS1/RAD51C 6 GO:0042306 regulation of protein import into nucleus 6/719 60/18722 0.0271663571656278 0.171459795225683 CDK1/RAN/HSP90AB1/NUTF2/ECT2/SUMO1 6 GO:0000380 alternative mRNA splicing, via spliceosome 7/719 77/18722 0.0282695729318215 0.177825796406038 HNRNPA1/SAP18/MAGOH/RBM8A/SRSF9/RBM17/HNRNPM 7 GO:0006367 transcription initiation from RNA polymerase II promoter 7/719 77/18722 0.0282695729318215 0.177825796406038 HMGB1/POLR2I/GTF2A2/SUB1/POLR2G/CDK4/TAF9 7 GO:0035307 positive regulation of protein dephosphorylation 5/719 45/18722 0.028359750387872 0.177825796406038 CALM2/PPIA/CALM1/HSP90AB1/PIN1 5 GO:0071364 cellular response to epidermal growth factor stimulus 5/719 45/18722 0.028359750387872 0.177825796406038 GSTP1/EEF1A1/MCM7/NCL/ID1 5 GO:0000956 nuclear-transcribed mRNA catabolic process 9/719 112/18722 0.0285269010644422 0.178583039183907 LSM4/LSM7/EXOSC8/MAGOH/RBM8A/SSB/POLR2G/MAGOHB/MRTO4 9 GO:0009314 response to radiation 26/719 456/18722 0.0296606769826971 0.185122754465975 PCNA/PBK/NPM1/RAD51/AURKB/RPL26/TXN/RAD51AP1/FEN1/RRM1/NUCKS1/EEF1D/PPP1CA/HMGN1/ADIRF/XRCC6/DYNLRB1/TRIAP1/ECT2/COPS3/CCND1/POLD3/PARP1/HRAS/BAX/USP1 26 GO:0018200 peptidyl-glutamic acid modification 4/719 31/18722 0.0298119760438712 0.185122754465975 CFAP20/PARP1/VKORC1/NAA10 4 GO:0032148 activation of protein kinase B activity 4/719 31/18722 0.0298119760438712 0.185122754465975 PPIA/TXN/PARK7/ITGB1BP1 4 GO:0044819 mitotic G1/S transition checkpoint signaling 4/719 31/18722 0.0298119760438712 0.185122754465975 RPL26/RPA2/TRIAP1/CCND1 4 GO:0071480 cellular response to gamma radiation 4/719 31/18722 0.0298119760438712 0.185122754465975 RAD51/RPL26/XRCC6/HRAS 4 GO:0006337 nucleosome disassembly 3/719 18/18722 0.0299316975205101 0.185566884788992 HMGA1/SET/SUPT16H 3 GO:0034637 cellular carbohydrate biosynthetic process 7/719 78/18722 0.0300686220588174 0.185817327329771 PTGES3/PPP1CA/PGP/IMPA2/AKR1B1/ISYNA1/UGP2 7 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 7/719 78/18722 0.0300686220588174 0.185817327329771 BIRC5/PARK7/PRDX5/BCL2L12/PRDX3/TRIAP1/PIH1D1 7 GO:0006195 purine nucleotide catabolic process 5/719 46/18722 0.0308482215394462 0.190025044682988 HINT1/DNPH1/NUDT8/NUDT15/PNP 5 GO:0043462 regulation of ATPase activity 5/719 46/18722 0.0308482215394462 0.190025044682988 PFN1/DNAJC9/CNN3/PPIF/AHSA1 5 GO:0007569 cell aging 10/719 132/18722 0.0310029002688142 0.190672789193186 CDK1/NPM1/HMGA1/MIF/YBX1/SOD1/ROMO1/CDKN2A/EEF1E1/HRAS 10 GO:0010038 response to metal ion 22/719 373/18722 0.0312744846711892 0.191924751837076 PCNA/MT2A/CDK1/CALM2/CALM1/DTYMK/CCNB1/SOD1/CACYBP/PARK7/CYB5A/HNRNPD/PPP1CA/NUDT1/CAV1/ECT2/CCND1/PPIF/CDK4/PARP1/SUMO1/BNIP3 22 GO:0007062 sister chromatid cohesion 6/719 62/18722 0.0313061673126451 0.191924751837076 FEN1/CDC20/RAD51C/PHB2/NAA10/SMC3 6 GO:1903008 organelle disassembly 9/719 114/18722 0.0314928245074585 0.192762121389054 CDK1/SLC25A5/PARK7/VDAC1/VRK1/PHB2/BNIP3/UFC1/MCTS1 9 GO:0006446 regulation of translational initiation 7/719 79/18722 0.0319431622875273 0.195208213979334 NPM1/RPL13A/PPP1CA/EIF3K/EIF3H/POLR2G/CDC123 7 GO:0050685 positive regulation of mRNA processing 4/719 32/18722 0.0330687607296309 0.201129113442463 CCNB1/PRDX6/NCL/RBM3 4 GO:0097345 mitochondrial outer membrane permeabilization 4/719 32/18722 0.0330687607296309 0.201129113442463 SLC25A5/VDAC2/BNIP3/BAX 4 GO:1903955 positive regulation of protein targeting to mitochondrion 4/719 32/18722 0.0330687607296309 0.201129113442463 UBE2L3/PDCD5/UBL5/SAE1 4 GO:0046902 regulation of mitochondrial membrane permeability 6/719 63/18722 0.0335220219381859 0.203564328804441 SLC25A5/DYNLT1/VDAC2/PPIF/BNIP3/BAX 6 GO:0018205 peptidyl-lysine modification 22/719 376/18722 0.0337373789591329 0.204549462980569 HINT1/GCSH/PARK7/TRMT112/HAT1/SUMO2/SET/MORF4L2/NDUFAB1/UBE2I/EZH2/HINT2/PIH1D1/DPY30/ACTL6A/SAE1/TAF9/SUMO1/DNMT1/YEATS4/RUVBL1/POLE3 22 GO:0006144 purine nucleobase metabolic process 3/719 19/18722 0.0345551010361054 0.207870529670321 PAICS/GMPS/APRT 3 GO:0009223 pyrimidine deoxyribonucleotide catabolic process 3/719 19/18722 0.0345551010361054 0.207870529670321 DUT/DCTPP1/UNG 3 GO:0046033 AMP metabolic process 3/719 19/18722 0.0345551010361054 0.207870529670321 APRT/AK2/ADK 3 GO:0046653 tetrahydrofolate metabolic process 3/719 19/18722 0.0345551010361054 0.207870529670321 TYMS/DHFR/ATIC 3 GO:0046794 transport of virus 3/719 19/18722 0.0345551010361054 0.207870529670321 KPNA2/DYNLT1/CAV1 3 GO:1905710 positive regulation of membrane permeability 5/719 48/18722 0.0362250618305807 0.217576424411444 SLC25A5/VDAC2/PPIF/BNIP3/BAX 5 GO:0010165 response to X-ray 4/719 33/18722 0.0365249747316768 0.218695416356074 RAD51/NUCKS1/XRCC6/CCND1 4 GO:1903146 regulation of autophagy of mitochondrion 4/719 33/18722 0.0365249747316768 0.218695416356074 SLC25A5/PARK7/VDAC1/BNIP3 4 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 8/719 99/18722 0.03664318693732 0.219062530603544 RPS3/RPL26/TPT1/MIF/TRIAP1/PHLDA3/TAF9/BAX 8 GO:0006606 protein import into nucleus 11/719 155/18722 0.0369198158406854 0.220032958183652 CDK1/RAN/RPL23/KPNA2/HSP90AB1/NUTF2/ECT2/NXT1/PHB2/SUMO1/CSE1L 11 GO:0046434 organophosphate catabolic process 11/719 155/18722 0.0369198158406854 0.220032958183652 DUT/HINT1/PRDX6/DCTPP1/UNG/IMPA2/DNPH1/NUDT8/NUDT15/PNP/NUDT5 11 GO:0071900 regulation of protein serine/threonine kinase activity 21/719 359/18722 0.0374787096857185 0.223018597047939 CKS1B/CALM2/GSTP1/RPS3/CCNA2/CDKN3/CCNB2/CALM1/CKS2/CDC6/CCNB1/CCNE1/HSP90AB1/CD24/EZH2/PKIB/CAV1/CDKN2A/PIH1D1/CCND1/HRAS 21 GO:0090307 mitotic spindle assembly 6/719 65/18722 0.0382520507711489 0.227269128810067 PRC1/AURKB/CDC20/TPX2/MZT1/SMC3 6 GO:0110020 regulation of actomyosin structure organization 8/719 100/18722 0.0385488639734511 0.228679701537422 STMN1/S100A10/PFN1/ACTG1/ECT2/RHOC/MKKS/ITGB1BP1 8 GO:0010823 negative regulation of mitochondrion organization 5/719 49/18722 0.0391161998307723 0.230910119586451 SLC25A5/PRELID1/TRIAP1/PPIF/BNIP3 5 GO:0070849 response to epidermal growth factor 5/719 49/18722 0.0391161998307723 0.230910119586451 GSTP1/EEF1A1/MCM7/NCL/ID1 5 GO:0006851 mitochondrial calcium ion transmembrane transport 3/719 20/18722 0.0395246152746679 0.230910119586451 VDAC1/STOML2/MCUR1 3 GO:0009129 pyrimidine nucleoside monophosphate metabolic process 3/719 20/18722 0.0395246152746679 0.230910119586451 TYMS/DUT/UMPS 3 GO:0010523 negative regulation of calcium ion transport into cytosol 3/719 20/18722 0.0395246152746679 0.230910119586451 CALM2/GSTO1/CALM1 3 GO:0031498 chromatin disassembly 3/719 20/18722 0.0395246152746679 0.230910119586451 HMGA1/SET/SUPT16H 3 GO:0071243 cellular response to arsenic-containing substance 3/719 20/18722 0.0395246152746679 0.230910119586451 GSTO1/HNRNPA1/PPIF 3 GO:0071731 response to nitric oxide 3/719 20/18722 0.0395246152746679 0.230910119586451 TXN/CCNA2/HNRNPD 3 GO:0090201 negative regulation of release of cytochrome c from mitochondria 3/719 20/18722 0.0395246152746679 0.230910119586451 PRELID1/TRIAP1/PPIF 3 GO:2000757 negative regulation of peptidyl-lysine acetylation 3/719 20/18722 0.0395246152746679 0.230910119586451 SET/HINT2/PIH1D1 3 GO:0031032 actomyosin structure organization 13/719 196/18722 0.0396131559256448 0.231076742899595 STMN1/CSRP2/S100A10/PFN1/PDLIM1/ACTG1/KRT19/KRT8/CNN3/ECT2/RHOC/MKKS/ITGB1BP1 13 GO:0006356 regulation of transcription by RNA polymerase I 4/719 34/18722 0.040181360280398 0.233330674328103 POLR2L/NCL/PIH1D1/POLR2K 4 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 4/719 34/18722 0.040181360280398 0.233330674328103 NPM1/RPL26/MIF/EEF1E1 4 GO:1990000 amyloid fibril formation 4/719 34/18722 0.040181360280398 0.233330674328103 PFDN2/PFDN4/VBP1/PFDN1 4 GO:0006576 cellular biogenic amine metabolic process 8/719 101/18722 0.0405197425269796 0.234941278206132 LY6E/PARK7/COMT/AKR1B1/SMS/ALDH7A1/PNKD/SRM 8 GO:0051302 regulation of cell division 12/719 177/18722 0.0406993303541332 0.235627702050245 CALM2/PRC1/AURKB/CALM1/CDC6/YBX1/AURKA/ORC6/ECT2/PIN1/ITGB1BP1/CDK2AP2 12 GO:0031331 positive regulation of cellular catabolic process 24/719 427/18722 0.040944028697617 0.236688454182921 HMGB1/SLC25A5/CDC20/PARK7/VDAC1/AURKA/PSMC3/RBX1/SUMO2/HNRNPD/EXOSC8/HSP90AA1/CAV1/PSMC1/BAG2/PSMC5/POLR2G/PHB2/SUMO1/HNRNPR/DDA1/BNIP3/RAD23A/BAX 24 GO:0007080 mitotic metaphase plate congression 5/719 50/18722 0.0421439528192544 0.242532463907518 AURKB/CDT1/NUF2/CCNB1/NUDC 5 GO:0043628 ncRNA 3'-end processing 5/719 50/18722 0.0421439528192544 0.242532463907518 EXOSC8/POLR3K/SSB/FBL/HSD17B10 5 GO:0071709 membrane assembly 5/719 50/18722 0.0421439528192544 0.242532463907518 S100A10/ANXA2/UBE2I/CAV1/NSFL1C 5 GO:0043967 histone H4 acetylation 6/719 67/18722 0.0433870497568541 0.249313644125206 HAT1/MORF4L2/PIH1D1/ACTL6A/YEATS4/RUVBL1 6 GO:0046165 alcohol biosynthetic process 10/719 140/18722 0.0436341448534582 0.250359847519842 SOD1/DHFR/PARK7/FDPS/PGP/IMPA2/AKR1B1/ISYNA1/PCBD1/PTS 10 GO:0006739 NADP metabolic process 4/719 35/18722 0.0440381588364554 0.251258184089207 PGAM1/IDH2/DCXR/TALDO1 4 GO:0040001 establishment of mitotic spindle localization 4/719 35/18722 0.0440381588364554 0.251258184089207 NUSAP1/MAD2L1/DYNLT1/NSFL1C 4 GO:0006475 internal protein amino acid acetylation 11/719 160/18722 0.044770053340527 0.251258184089207 PARK7/HAT1/SET/MORF4L2/PIH1D1/ACTL6A/TAF9/YEATS4/NAA10/RUVBL1/POLE3 11 GO:0043271 negative regulation of ion transport 11/719 160/18722 0.044770053340527 0.251258184089207 CALM2/GSTO1/CALM1/VDAC1/YWHAE/CAV1/YWHAQ/C4orf3/PPIF/SUMO1/ISCU 11 GO:2000779 regulation of double-strand break repair 7/719 85/18722 0.0448330356961072 0.251258184089207 RAD51/DEK/RAD51AP1/RMI2/RPA2/PARP1/PPP4C 7 GO:0006244 pyrimidine nucleotide catabolic process 3/719 21/18722 0.0448349019400741 0.251258184089207 DUT/DCTPP1/UNG 3 GO:0032516 positive regulation of phosphoprotein phosphatase activity 3/719 21/18722 0.0448349019400741 0.251258184089207 CALM2/CALM1/HSP90AB1 3 GO:0034312 diol biosynthetic process 3/719 21/18722 0.0448349019400741 0.251258184089207 DHFR/PCBD1/PTS 3 GO:0044766 multi-organism transport 3/719 21/18722 0.0448349019400741 0.251258184089207 KPNA2/DYNLT1/CAV1 3 GO:0046128 purine ribonucleoside metabolic process 3/719 21/18722 0.0448349019400741 0.251258184089207 PNP/APRT/ADK 3 GO:0046823 negative regulation of nucleocytoplasmic transport 3/719 21/18722 0.0448349019400741 0.251258184089207 TXN/PARK7/SUMO1 3 GO:0070584 mitochondrion morphogenesis 3/719 21/18722 0.0448349019400741 0.251258184089207 SSBP1/SLIRP/BAX 3 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 3/719 21/18722 0.0448349019400741 0.251258184089207 MIF/TRIAP1/TAF9 3 GO:1902579 multi-organism localization 3/719 21/18722 0.0448349019400741 0.251258184089207 KPNA2/DYNLT1/CAV1 3 GO:1903427 negative regulation of reactive oxygen species biosynthetic process 3/719 21/18722 0.0448349019400741 0.251258184089207 PAGE4/PARK7/HSPD1 3 GO:2000774 positive regulation of cellular senescence 3/719 21/18722 0.0448349019400741 0.251258184089207 HMGA1/CDKN2A/EEF1E1 3 GO:0051293 establishment of spindle localization 5/719 51/18722 0.0453091425108153 0.253304860109592 NUSAP1/MAD2L1/CFL1/DYNLT1/NSFL1C 5 GO:0071902 positive regulation of protein serine/threonine kinase activity 13/719 200/18722 0.0453317009390932 0.253304860109592 CKS1B/CALM2/RPS3/CALM1/CKS2/CDC6/CCNB1/HSP90AB1/CD24/EZH2/PIH1D1/CCND1/HRAS 13 GO:0072329 monocarboxylic acid catabolic process 9/719 122/18722 0.0454890990711684 0.253815987571012 ACAT2/ECHS1/ETFB/ECH1/ECI1/NUDT8/HADH/ETFA/HSD17B10 9 GO:0051926 negative regulation of calcium ion transport 6/719 68/18722 0.0461086751441349 0.256900722583096 CALM2/GSTO1/CALM1/VDAC1/YWHAE/C4orf3 6 GO:0032413 negative regulation of ion transmembrane transporter activity 7/719 86/18722 0.047263261966596 0.2625736775922 CALM2/GSTO1/CALM1/YWHAE/CAV1/C4orf3/SUMO1 7 GO:2000117 negative regulation of cysteine-type endopeptidase activity 7/719 86/18722 0.047263261966596 0.2625736775922 BIRC5/PARK7/PRDX5/BCL2L12/PRDX3/TRIAP1/PIH1D1 7 GO:0071482 cellular response to light stimulus 9/719 123/18722 0.0474890422809863 0.26344785703429 PCNA/PBK/NPM1/AURKB/RPL26/TRIAP1/POLD3/PARP1/BAX 9 GO:0051385 response to mineralocorticoid 4/719 36/18722 0.0480951293034433 0.265661761575691 RPL27/CALM1/CCND1/PARP1 4 GO:0070897 transcription preinitiation complex assembly 4/719 36/18722 0.0480951293034433 0.265661761575691 HMGB1/PIH1D1/GTF2A2/TAF9 4 GO:1903749 positive regulation of establishment of protein localization to mitochondrion 4/719 36/18722 0.0480951293034433 0.265661761575691 UBE2L3/PDCD5/UBL5/SAE1 4 GO:2000378 negative regulation of reactive oxygen species metabolic process 5/719 52/18722 0.0486123683301932 0.268134123311237 PAGE4/PARK7/VDAC1/HSPD1/BNIP3 5 GO:0032231 regulation of actin filament bundle assembly 8/719 105/18722 0.0490687704771711 0.269878237624441 STMN1/S100A10/PFN1/ACTG1/RHOC/MKKS/ID1/ITGB1BP1 8 GO:2001022 positive regulation of response to DNA damage stimulus 8/719 105/18722 0.0490687704771711 0.269878237624441 PCNA/HMGB1/RPS3/RPL26/RAD51AP1/UBE2N/EEF1E1/PARP1 8 GO:0051262 protein tetramerization 7/719 87/18722 0.0497759432741545 0.273377149223245 TK1/RRM2/ALDOA/RRM1/SSBP1/KRT10/HSD17B10 7 GO:0009220 pyrimidine ribonucleotide biosynthetic process 3/719 22/18722 0.0504794512583598 0.27488810091186 NME1/NME4/UMPS 3 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 3/719 22/18722 0.0504794512583598 0.27488810091186 CALM2/GSTO1/CALM1 3 GO:0019400 alditol metabolic process 3/719 22/18722 0.0504794512583598 0.27488810091186 TPI1/PGP/AKR1B1 3 GO:0021854 hypothalamus development 3/719 22/18722 0.0504794512583598 0.27488810091186 UQCRQ/UBB/BAX 3 GO:0048026 positive regulation of mRNA splicing, via spliceosome 3/719 22/18722 0.0504794512583598 0.27488810091186 PRDX6/NCL/RBM3 3 GO:0055093 response to hyperoxia 3/719 22/18722 0.0504794512583598 0.27488810091186 CAV1/CDK4/BNIP3 3 GO:0032984 protein-containing complex disassembly 14/719 224/18722 0.0509441622268746 0.277026870866479 STMN1/HMGA1/CALM1/TPX2/CFL1/RPL23/DSTN/PPP1CA/SET/CKAP2/EIF5A/VAMP8/BNIP3/SUPT16H 14 GO:0010821 regulation of mitochondrion organization 10/719 144/18722 0.05110155828732 0.277490831320426 SLC25A5/PARK7/VDAC1/AURKA/PRELID1/PDCD5/TRIAP1/PPIF/BNIP3/BAX 10 GO:0030038 contractile actin filament bundle assembly 8/719 106/18722 0.05137538190198 0.27819299623435 STMN1/S100A10/PFN1/PDLIM1/ACTG1/RHOC/MKKS/ITGB1BP1 8 GO:0043149 stress fiber assembly 8/719 106/18722 0.05137538190198 0.27819299623435 STMN1/S100A10/PFN1/PDLIM1/ACTG1/RHOC/MKKS/ITGB1BP1 8 GO:0016925 protein sumoylation 5/719 53/18722 0.0520540099859946 0.281471823660223 PARK7/SUMO2/UBE2I/SAE1/SUMO1 5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4/719 37/18722 0.0523515672547868 0.28228786264836 RPS16/RPS19/RPS8/RPS14 4 GO:0045730 respiratory burst 4/719 37/18722 0.0523515672547868 0.28228786264836 PRDX2/RPS19/PGAM1/CD24 4 GO:0000018 regulation of DNA recombination 8/719 107/18722 0.0537507617324547 0.282580389330725 RAD51/RAD51AP1/KPNA2/RMI2/RPA2/ALYREF/PARP1/PPP4C 8 GO:0021761 limbic system development 8/719 107/18722 0.0537507617324547 0.282580389330725 UQCRQ/NME1/ANXA3/UBB/EZH2/ARPC5/MKKS/BAX 8 GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 8/719 107/18722 0.0537507617324547 0.282580389330725 CDC20/AURKA/RBX1/SUMO2/CAV1/SUMO1/DDA1/RAD23A 8 GO:0071214 cellular response to abiotic stimulus 19/719 331/18722 0.0537667544727586 0.282580389330725 PCNA/PBK/NPM1/RAD51/AURKB/RPL26/RAD51AP1/NUCKS1/EEF1D/ADIRF/XRCC6/TRIAP1/AKR1B1/ECT2/POLD3/PARP1/HRAS/BNIP3/BAX 19 GO:0104004 cellular response to environmental stimulus 19/719 331/18722 0.0537667544727586 0.282580389330725 PCNA/PBK/NPM1/RAD51/AURKB/RPL26/RAD51AP1/NUCKS1/EEF1D/ADIRF/XRCC6/TRIAP1/AKR1B1/ECT2/POLD3/PARP1/HRAS/BNIP3/BAX 19 GO:0000255 allantoin metabolic process 2/719 10/18722 0.0540205627395879 0.282580389330725 DNPH1/PNP 2 GO:0006228 UTP biosynthetic process 2/719 10/18722 0.0540205627395879 0.282580389330725 NME1/NME4 2 GO:0006283 transcription-coupled nucleotide-excision repair 2/719 10/18722 0.0540205627395879 0.282580389330725 HMGN1/POLR2I 2 GO:0009133 nucleoside diphosphate biosynthetic process 2/719 10/18722 0.0540205627395879 0.282580389330725 DTYMK/AK2 2 GO:0009170 purine deoxyribonucleoside monophosphate metabolic process 2/719 10/18722 0.0540205627395879 0.282580389330725 DNPH1/PNP 2 GO:0009396 folic acid-containing compound biosynthetic process 2/719 10/18722 0.0540205627395879 0.282580389330725 DHFR/ATIC 2 GO:0010992 ubiquitin recycling 2/719 10/18722 0.0540205627395879 0.282580389330725 UBE2C/UBE2S 2 GO:0017085 response to insecticide 2/719 10/18722 0.0540205627395879 0.282580389330725 UBA52/CCNB1 2 GO:0030638 polyketide metabolic process 2/719 10/18722 0.0540205627395879 0.282580389330725 AKR7A2/AKR1B1 2 GO:0030647 aminoglycoside antibiotic metabolic process 2/719 10/18722 0.0540205627395879 0.282580389330725 AKR7A2/AKR1B1 2 GO:0031118 rRNA pseudouridine synthesis 2/719 10/18722 0.0540205627395879 0.282580389330725 NHP2/NOP10 2 GO:0044598 doxorubicin metabolic process 2/719 10/18722 0.0540205627395879 0.282580389330725 AKR7A2/AKR1B1 2 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 2/719 10/18722 0.0540205627395879 0.282580389330725 CALM2/CALM1 2 GO:0051409 response to nitrosative stress 2/719 10/18722 0.0540205627395879 0.282580389330725 PARK7/ADH5 2 GO:1901524 regulation of mitophagy 2/719 10/18722 0.0540205627395879 0.282580389330725 SLC25A5/VDAC1 2 GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 2/719 10/18722 0.0540205627395879 0.282580389330725 NCL/PIH1D1 2 GO:2000434 regulation of protein neddylation 2/719 10/18722 0.0540205627395879 0.282580389330725 RPL11/RPL5 2 GO:1900407 regulation of cellular response to oxidative stress 7/719 89/18722 0.0550508156301816 0.287578887620352 PPIA/PAGE4/TXN/SOD1/DHFR/PARK7/PARP1 7 GO:0006584 catecholamine metabolic process 5/719 54/18722 0.0556342306336527 0.28944836208049 LY6E/PARK7/COMT/AKR1B1/PNKD 5 GO:0009712 catechol-containing compound metabolic process 5/719 54/18722 0.0556342306336527 0.28944836208049 LY6E/PARK7/COMT/AKR1B1/PNKD 5 GO:0010524 positive regulation of calcium ion transport into cytosol 5/719 54/18722 0.0556342306336527 0.28944836208049 CALM2/GSTO1/CALM1/CAV1/BAX 5 GO:0008033 tRNA processing 9/719 127/18722 0.056067945662147 0.29130011951699 TRMT112/TPRKB/POP7/POLR3K/TSEN34/LSM6/RPP30/SSB/HSD17B10 9 GO:0044282 small molecule catabolic process 21/719 376/18722 0.0561414775796381 0.29130011951699 ENO1/TPI1/GCSH/PARK7/ACAT2/ECHS1/ETFB/ECH1/ECI1/IMPA2/NUDT1/NUDT8/ADH5/HADH/PNKD/PNP/QPRT/NUDT5/ETFA/ESD/HSD17B10 21 GO:0002082 regulation of oxidative phosphorylation 3/719 23/18722 0.0564507203724804 0.292510462226177 UQCC2/COX7A2/PPIF 3 GO:0071398 cellular response to fatty acid 4/719 38/18722 0.0568063249708988 0.293562887433504 CCNB1/NME1/CDK4/ID3 4 GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 4/719 38/18722 0.0568063249708988 0.293562887433504 SLC25A5/VDAC2/BNIP3/BAX 4 GO:0031960 response to corticosteroid 11/719 167/18722 0.0575745756744224 0.297134204217863 TYMS/PCNA/HMGB1/GSTP1/RPL27/CALM1/ANXA3/UBE2L3/HSPD1/CCND1/PARP1 11 GO:0022411 cellular component disassembly 24/719 443/18722 0.05774217067874 0.297600210325501 STMN1/CDK1/TOP2A/SLC25A5/HMGA1/CALM1/TPX2/PARK7/CFL1/VDAC1/RPL23/DSTN/VRK1/PPP1CA/SET/CKAP2/EIF5A/VAMP8/PHB2/BNIP3/SUPT16H/UFC1/BAX/MCTS1 24 GO:0032410 negative regulation of transporter activity 8/719 109/18722 0.0587094963441974 0.302181231183369 CALM2/GSTO1/CALM1/YWHAE/CAV1/C4orf3/PPIF/SUMO1 8 GO:0044091 membrane biogenesis 5/719 55/18722 0.0593529805816224 0.305085414204601 S100A10/ANXA2/UBE2I/CAV1/NSFL1C 5 GO:0006354 DNA-templated transcription, elongation 7/719 91/18722 0.0606612094515221 0.310405612572888 CDCA4/HMGN1/ENY2/EZH2/POLR2I/ALYREF/SUPT16H 7 GO:0051492 regulation of stress fiber assembly 7/719 91/18722 0.0606612094515221 0.310405612572888 STMN1/S100A10/PFN1/ACTG1/RHOC/MKKS/ITGB1BP1 7 GO:0034101 erythrocyte homeostasis 9/719 129/18722 0.0607105003291908 0.310405612572888 HMGB2/SLC25A5/RPS6/RPS19/RPS14/RPS24/PRDX1/RPS17/PRMT1 9 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 9/719 129/18722 0.0607105003291908 0.310405612572888 HMGB1/RPS3/HSPE1/ANP32B/PDCD5/HSPD1/NDUFA13/CYCS/BAX 9 GO:0048872 homeostasis of number of cells 16/719 272/18722 0.0608129717979288 0.31051716368969 HMGB2/HMGB1/PRDX2/SLC25A5/RPS6/RPS19/RPS14/RPS24/PRDX1/CCNB2/RPS17/SOD1/EZH2/PRMT1/FH/BAX 16 GO:0045739 positive regulation of DNA repair 6/719 73/18722 0.0612823254613284 0.312499275531277 PCNA/HMGB1/RPS3/RAD51AP1/UBE2N/PARP1 6 GO:0018394 peptidyl-lysine acetylation 11/719 169/18722 0.0616365533308706 0.31388985492573 PARK7/HAT1/SET/MORF4L2/HINT2/PIH1D1/ACTL6A/TAF9/YEATS4/RUVBL1/POLE3 11 GO:0045732 positive regulation of protein catabolic process 14/719 231/18722 0.0625415578473935 0.316579300203725 CDC20/AURKA/PSMC3/RBX1/SUMO2/HSP90AA1/CAV1/PSMC1/BAG2/PSMC5/NDUFA13/SUMO1/DDA1/RAD23A 14 GO:0006213 pyrimidine nucleoside metabolic process 3/719 24/18722 0.0627402613131019 0.316579300203725 TK1/ERH/DTYMK 3 GO:0044321 response to leptin 3/719 24/18722 0.0627402613131019 0.316579300203725 CCNA2/CCND1/MKKS 3 GO:0051123 RNA polymerase II preinitiation complex assembly 3/719 24/18722 0.0627402613131019 0.316579300203725 HMGB1/GTF2A2/TAF9 3 GO:0070129 regulation of mitochondrial translation 3/719 24/18722 0.0627402613131019 0.316579300203725 UQCC2/C1QBP/COA3 3 GO:0072530 purine-containing compound transmembrane transport 3/719 24/18722 0.0627402613131019 0.316579300203725 SLC25A5/SLC25A6/SLC29A1 3 GO:0090343 positive regulation of cell aging 3/719 24/18722 0.0627402613131019 0.316579300203725 HMGA1/CDKN2A/EEF1E1 3 GO:0006352 DNA-templated transcription, initiation 9/719 130/18722 0.0631212213998744 0.316978440353942 HMGB1/POLR2I/PIH1D1/GTF2A2/SUB1/POLR2G/CDK4/TAF9/TFAM 9 GO:0043470 regulation of carbohydrate catabolic process 5/719 56/18722 0.0632100014960332 0.316978440353942 HMGB1/PGAM1/ARL2/PPP1CA/EIF6 5 GO:0051653 spindle localization 5/719 56/18722 0.0632100014960332 0.316978440353942 NUSAP1/MAD2L1/CFL1/DYNLT1/NSFL1C 5 GO:1902903 regulation of supramolecular fiber organization 21/719 382/18722 0.0640738235057897 0.316978440353942 STMN1/S100A10/RPS3/PFN1/ACTG1/TPX2/PARK7/DSTN/ARL2/CKAP2/ARPC1A/ARPC5/RHOC/ARPC5L/PFDN2/MKKS/PFDN4/ID1/ITGB1BP1/VBP1/PFDN1 21 GO:0097305 response to alcohol 15/719 253/18722 0.0643377828577687 0.316978440353942 TYMS/CDK1/GSTP1/RAD51/RPL15/RPL10A/RPL27/EEF1B2/CALM1/SOD1/HNRNPD/PSMD14/CCND1/CDK4/PARP1 15 GO:0019058 viral life cycle 18/719 317/18722 0.0643597704242567 0.316978440353942 CDK1/PPIA/TOP2A/RPSA/DEK/SIVA1/NUCKS1/LY6E/KPNA2/DYNLT1/BANF1/HSP90AB1/CAV1/VAMP8/SNX3/PHB/PPIH/RAD23A 18 GO:0006020 inositol metabolic process 2/719 11/18722 0.0643836728199435 0.316978440353942 IMPA2/ISYNA1 2 GO:0009128 purine nucleoside monophosphate catabolic process 2/719 11/18722 0.0643836728199435 0.316978440353942 DNPH1/PNP 2 GO:0033483 gas homeostasis 2/719 11/18722 0.0643836728199435 0.316978440353942 GSTP1/CAV1 2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase 2/719 11/18722 0.0643836728199435 0.316978440353942 ETFB/ETFA 2 GO:0045793 positive regulation of cell size 2/719 11/18722 0.0643836728199435 0.316978440353942 HSP90AB1/CDK4 2 GO:0046940 nucleoside monophosphate phosphorylation 2/719 11/18722 0.0643836728199435 0.316978440353942 DTYMK/AK2 2 GO:0048102 autophagic cell death 2/719 11/18722 0.0643836728199435 0.316978440353942 PHB2/BNIP3 2 GO:0051561 positive regulation of mitochondrial calcium ion concentration 2/719 11/18722 0.0643836728199435 0.316978440353942 BNIP3/MCUR1 2 GO:0051573 negative regulation of histone H3-K9 methylation 2/719 11/18722 0.0643836728199435 0.316978440353942 PIH1D1/DNMT1 2 GO:0055015 ventricular cardiac muscle cell development 2/719 11/18722 0.0643836728199435 0.316978440353942 CDK1/CCNB1 2 GO:0071888 macrophage apoptotic process 2/719 11/18722 0.0643836728199435 0.316978440353942 CDKN2A/TCP1 2 GO:0075733 intracellular transport of virus 2/719 11/18722 0.0643836728199435 0.316978440353942 KPNA2/DYNLT1 2 GO:1905522 negative regulation of macrophage migration 2/719 11/18722 0.0643836728199435 0.316978440353942 MIF/DDT 2 GO:1903201 regulation of oxidative stress-induced cell death 6/719 74/18722 0.0646325253996792 0.317797219398167 PPIA/PAGE4/TXN/SOD1/PARK7/PARP1 6 GO:0048545 response to steroid hormone 19/719 339/18722 0.0649317726937083 0.318861383763746 TYMS/HMGB2/PCNA/HMGB1/GSTP1/RPL27/CALM1/YWHAH/PTGES3/PARK7/ANXA3/UBE2L3/HSPD1/RBBP7/CAV1/PHB/CCND1/PARP1/PHB2 19 GO:0051258 protein polymerization 17/719 296/18722 0.0651256278603441 0.319405945557102 STMN1/UBE2C/RPS3/PFN1/UBE2S/TPX2/GPX4/ARL2/TUBG1/HSP90AA1/DIAPH3/ARPC1A/VDAC2/ARPC5/ARPC5L/MKKS/MZT1 17 GO:0031297 replication fork processing 4/719 40/18722 0.0663041167888556 0.323947778727277 PCNA/RAD51/NUCKS1/ALYREF 4 GO:0044275 cellular carbohydrate catabolic process 4/719 40/18722 0.0663041167888556 0.323947778727277 HMGB1/TPI1/PGAM1/PPP1CA 4 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 4/719 40/18722 0.0663041167888556 0.323947778727277 CALM2/GSTO1/CALM1/BAX 4 GO:0045132 meiotic chromosome segregation 7/719 93/18722 0.0666095028264485 0.3250273585321 PTTG1/TOP2A/NUF2/CCNE1/RAD51C/SMC2/SMC4 7 GO:0051785 positive regulation of nuclear division 5/719 57/18722 0.0672048310601812 0.327517214660377 NUSAP1/ANAPC11/CDT1/RAD51AP1/AURKA 5 GO:0016573 histone acetylation 10/719 152/18722 0.068474981803497 0.33286449487811 PARK7/HAT1/SET/MORF4L2/PIH1D1/ACTL6A/TAF9/YEATS4/RUVBL1/POLE3 10 GO:0090501 RNA phosphodiester bond hydrolysis 10/719 152/18722 0.068474981803497 0.33286449487811 FEN1/RNASEH2A/NHP2/EXOSC8/POP7/POLR3K/TSEN34/POLR2I/RPP30/APEX1 10 GO:0006312 mitotic recombination 3/719 25/18722 0.0693388391985883 0.334110802145889 RAD51/RAD51C/TPRKB 3 GO:0031579 membrane raft organization 3/719 25/18722 0.0693388391985883 0.334110802145889 S100A10/ANXA2/CAV1 3 GO:0033233 regulation of protein sumoylation 3/719 25/18722 0.0693388391985883 0.334110802145889 PARK7/UBE2I/SAE1 3 GO:0051291 protein heterooligomerization 3/719 25/18722 0.0693388391985883 0.334110802145889 RRM2/RRM1/KRT10 3 GO:0060706 cell differentiation involved in embryonic placenta development 3/719 25/18722 0.0693388391985883 0.334110802145889 KRT19/KRT8/MDFI 3 GO:0086064 cell communication by electrical coupling involved in cardiac conduction 3/719 25/18722 0.0693388391985883 0.334110802145889 CALM2/CALM1/CAV1 3 GO:1903901 negative regulation of viral life cycle 3/719 25/18722 0.0693388391985883 0.334110802145889 PPIA/LY6E/SNX3 3 GO:0044106 cellular amine metabolic process 8/719 113/18722 0.0694678058901921 0.33431381584655 LY6E/PARK7/COMT/AKR1B1/SMS/ALDH7A1/PNKD/SRM 8 GO:0051702 biological process involved in interaction with symbiont 7/719 94/18722 0.0697107818803174 0.334646521495289 GAPDH/NUCKS1/CFL1/PSMC3/HSPD1/ROMO1/PHB 7 GO:1990830 cellular response to leukemia inhibitory factor 7/719 94/18722 0.0697107818803174 0.334646521495289 SLC25A5/RPS16/CACYBP/SRSF3/HELLS/NCL/SRM 7 GO:0007131 reciprocal meiotic recombination 5/719 58/18722 0.0713368080465123 0.340752743150214 TOP2A/RAD51/MND1/RAD51AP1/RAD51C 5 GO:0032387 negative regulation of intracellular transport 5/719 58/18722 0.0713368080465123 0.340752743150214 TXN/PARK7/SNX3/SUMO1/ITGB1BP1 5 GO:0032481 positive regulation of type I interferon production 5/719 58/18722 0.0713368080465123 0.340752743150214 HMGB2/HMGB1/GAPDH/HSPD1/HSP90AA1 5 GO:0140527 reciprocal homologous recombination 5/719 58/18722 0.0713368080465123 0.340752743150214 TOP2A/RAD51/MND1/RAD51AP1/RAD51C 5 GO:0052548 regulation of endopeptidase activity 23/719 432/18722 0.0722413013602568 0.344645613676566 HMGB1/PTTG1/GAPDH/BIRC5/RPS3/HSPE1/PEBP1/PARK7/ANXA2/PRDX5/PRELID1/ANP32B/BCL2L12/PDCD5/HSPD1/PSMA3/PRDX3/TRIAP1/PSMD14/PIH1D1/NDUFA13/CYCS/BAX 23 GO:0019751 polyol metabolic process 8/719 114/18722 0.0723338422209645 0.344660015533061 TPI1/DHFR/PGP/IMPA2/AKR1B1/ISYNA1/PCBD1/PTS 8 GO:1990823 response to leukemia inhibitory factor 7/719 95/18722 0.0728968925127335 0.346913518138472 SLC25A5/RPS16/CACYBP/SRSF3/HELLS/NCL/SRM 7 GO:0001701 in utero embryonic development 20/719 367/18722 0.0743646508471318 0.350117960233426 NASP/RRM2/RPL13/ASF1B/CCNB2/KRT19/CCNB1/YBX1/LY6E/BTF3/KRT8/EIF2S2/SF3B6/PHLDA2/COPS3/ACTL6A/MDFI/PRMT1/NDUFA2/RNASEH2B 20 GO:0002424 T cell mediated immune response to tumor cell 2/719 12/18722 0.0753462714552121 0.350117960233426 HMGB1/HSPD1 2 GO:0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process 2/719 12/18722 0.0753462714552121 0.350117960233426 TYMS/DUT 2 GO:0009886 post-embryonic animal morphogenesis 2/719 12/18722 0.0753462714552121 0.350117960233426 HMGN1/BAX 2 GO:0032096 negative regulation of response to food 2/719 12/18722 0.0753462714552121 0.350117960233426 NENF/MKKS 2 GO:0032099 negative regulation of appetite 2/719 12/18722 0.0753462714552121 0.350117960233426 NENF/MKKS 2 GO:0032105 negative regulation of response to extracellular stimulus 2/719 12/18722 0.0753462714552121 0.350117960233426 NENF/MKKS 2 GO:0032108 negative regulation of response to nutrient levels 2/719 12/18722 0.0753462714552121 0.350117960233426 NENF/MKKS 2 GO:0032780 negative regulation of ATPase activity 2/719 12/18722 0.0753462714552121 0.350117960233426 CNN3/PPIF 2 GO:0033182 regulation of histone ubiquitination 2/719 12/18722 0.0753462714552121 0.350117960233426 PARK7/UBE2N 2 GO:0046051 UTP metabolic process 2/719 12/18722 0.0753462714552121 0.350117960233426 NME1/NME4 2 GO:0051255 spindle midzone assembly 2/719 12/18722 0.0753462714552121 0.350117960233426 PRC1/AURKB 2 GO:0071472 cellular response to salt stress 2/719 12/18722 0.0753462714552121 0.350117960233426 XRCC6/AKR1B1 2 GO:0071635 negative regulation of transforming growth factor beta production 2/719 12/18722 0.0753462714552121 0.350117960233426 HSP90AB1/CD24 2 GO:1905709 negative regulation of membrane permeability 2/719 12/18722 0.0753462714552121 0.350117960233426 DYNLT1/BNIP3 2 GO:0035306 positive regulation of dephosphorylation 5/719 59/18722 0.0756050777601117 0.350117960233426 CALM2/PPIA/CALM1/HSP90AB1/PIN1 5 GO:0051353 positive regulation of oxidoreductase activity 5/719 59/18722 0.0756050777601117 0.350117960233426 CALM1/DHFR/PARK7/NDUFA4/COX17 5 GO:2001258 negative regulation of cation channel activity 5/719 59/18722 0.0756050777601117 0.350117960233426 CALM2/GSTO1/CALM1/CAV1/SUMO1 5 GO:0051656 establishment of organelle localization 21/719 390/18722 0.075813643190301 0.350117960233426 NUSAP1/RAN/MAD2L1/NPM1/AURKB/RPS15/CDT1/NUF2/CCNB1/CFL1/DYNLT1/UBB/HSBP1/NUDC/S100A13/VAMP8/EIF6/MKKS/UXT/AP1M2/NSFL1C 21 GO:0006760 folic acid-containing compound metabolic process 3/719 26/18722 0.076236541280469 0.350117960233426 TYMS/DHFR/ATIC 3 GO:0031167 rRNA methylation 3/719 26/18722 0.076236541280469 0.350117960233426 TRMT112/METTL5/FBL 3 GO:0033598 mammary gland epithelial cell proliferation 3/719 26/18722 0.076236541280469 0.350117960233426 CCND1/PHB2/BAX 3 GO:0034643 establishment of mitochondrion localization, microtubule-mediated 3/719 26/18722 0.076236541280469 0.350117960233426 UBB/HSBP1/UXT 3 GO:0047497 mitochondrion transport along microtubule 3/719 26/18722 0.076236541280469 0.350117960233426 UBB/HSBP1/UXT 3 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 3/719 26/18722 0.076236541280469 0.350117960233426 CALM2/GSTO1/CALM1 3 GO:1904353 regulation of telomere capping 3/719 26/18722 0.076236541280469 0.350117960233426 AURKB/HNRNPD/PKIB 3 GO:2000108 positive regulation of leukocyte apoptotic process 3/719 26/18722 0.076236541280469 0.350117960233426 PRELID1/CDKN2A/BAX 3 GO:0033574 response to testosterone 4/719 42/18722 0.0765712526016998 0.350117960233426 NASP/NME1/CSNK2B/CDK4 4 GO:0045214 sarcomere organization 4/719 42/18722 0.0765712526016998 0.350117960233426 CSRP2/ACTG1/KRT19/KRT8 4 GO:0045292 mRNA cis splicing, via spliceosome 4/719 42/18722 0.0765712526016998 0.350117960233426 SNRPC/PSIP1/RBM17/CWC15 4 GO:0046688 response to copper ion 4/719 42/18722 0.0765712526016998 0.350117960233426 MT2A/CDK1/SOD1/PARK7 4 GO:0072595 maintenance of protein localization in organelle 4/719 42/18722 0.0765712526016998 0.350117960233426 TXN/PARK7/ARL2/SKP1 4 GO:0090317 negative regulation of intracellular protein transport 4/719 42/18722 0.0765712526016998 0.350117960233426 TXN/PARK7/SUMO1/ITGB1BP1 4 GO:0051222 positive regulation of protein transport 17/719 303/18722 0.0770031921937512 0.351675314289374 CDK1/RAN/PPIA/PHPT1/DYNLL1/MPC2/ANP32B/HSP90AB1/UBE2L3/YWHAE/PDCD5/UBL5/NUTF2/ECT2/SAE1/HRAS/ITGB1BP1 17 GO:0010952 positive regulation of peptidase activity 12/719 197/18722 0.0780044704967174 0.355728622875931 HMGB1/RPS3/HSPE1/PRELID1/ANP32B/PDCD5/HSPD1/CAV1/PSMD14/NDUFA13/CYCS/BAX 12 GO:0048732 gland development 23/719 436/18722 0.0780755029428992 0.355728622875931 TYMS/PCNA/PRDX2/RPS16/RPS15/RPL19/CCNB2/SOD1/NME1/LY6E/KRT18/AURKA/HNRNPD/CSNK2B/EZH2/CAV1/CCND1/PHB2/APRT/SLC29A1/HRAS/UMPS/BAX 23 GO:0090559 regulation of membrane permeability 6/719 78/18722 0.0790853514053351 0.359903785946265 SLC25A5/DYNLT1/VDAC2/PPIF/BNIP3/BAX 6 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 5/719 60/18722 0.0800085978141556 0.363675444609798 CDK1/AURKB/CLSPN/CDC6/NAE1 5 GO:0097191 extrinsic apoptotic signaling pathway 13/719 219/18722 0.0803068301667117 0.364600585072924 HMGB2/PRDX2/GSTP1/SIVA1/PARK7/KRT8/KRT18/BCL2L12/PPP1CA/CAV1/NDUFA13/FAIM/BAX 13 GO:0045471 response to ethanol 9/719 137/18722 0.0816855771060623 0.370423406193569 TYMS/CDK1/GSTP1/RPL15/RPL10A/EEF1B2/SOD1/PSMD14/CCND1 9 GO:0052547 regulation of peptidase activity 24/719 461/18722 0.0819116936564476 0.370478207037762 HMGB1/PTTG1/GAPDH/BIRC5/RPS3/HSPE1/PEBP1/PARK7/ANXA2/PRDX5/PRELID1/ANP32B/BCL2L12/PDCD5/HSPD1/PSMA3/PRDX3/TRIAP1/CAV1/PSMD14/PIH1D1/NDUFA13/CYCS/BAX 24 GO:0006458 'de novo' protein folding 4/719 43/18722 0.081986346076928 0.370478207037762 HSPE1/PTGES3/HSPD1/CCT2 4 GO:0045840 positive regulation of mitotic nuclear division 4/719 43/18722 0.081986346076928 0.370478207037762 NUSAP1/ANAPC11/CDT1/AURKA 4 GO:1902882 regulation of response to oxidative stress 7/719 98/18722 0.082963510351743 0.373485586159461 PPIA/PAGE4/TXN/SOD1/DHFR/PARK7/PARP1 7 GO:0008053 mitochondrial fusion 3/719 27/18722 0.0834228774157333 0.373485586159461 STOML2/BNIP3/BAX 3 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 3/719 27/18722 0.0834228774157333 0.373485586159461 CALM2/GSTO1/CALM1 3 GO:0032781 positive regulation of ATPase activity 3/719 27/18722 0.0834228774157333 0.373485586159461 PFN1/DNAJC9/AHSA1 3 GO:0032786 positive regulation of DNA-templated transcription, elongation 3/719 27/18722 0.0834228774157333 0.373485586159461 HMGN1/ALYREF/SUPT16H 3 GO:0039529 RIG-I signaling pathway 3/719 27/18722 0.0834228774157333 0.373485586159461 C1QBP/PHB/PHB2 3 GO:0042104 positive regulation of activated T cell proliferation 3/719 27/18722 0.0834228774157333 0.373485586159461 HMGB1/RPS3/CD24 3 GO:0009410 response to xenobiotic stimulus 24/719 462/18722 0.0834279491161392 0.373485586159461 TYMS/PCNA/CDK1/LDHA/GSTO1/GSTP1/S100A10/RAD51/CCNB1/MCM7/SOD1/NME1/COMT/HSP90AB1/HSPD1/ADIRF/HADH/NUDT15/PNP/APEX1/TXN2/VKORC1/UMPS/CYB5B 24 GO:0018393 internal peptidyl-lysine acetylation 10/719 158/18722 0.0837051053164742 0.373856908896086 PARK7/HAT1/SET/MORF4L2/PIH1D1/ACTL6A/TAF9/YEATS4/RUVBL1/POLE3 10 GO:0043488 regulation of mRNA stability 10/719 158/18722 0.0837051053164742 0.373856908896086 NPM1/CARHSP1/YBX1/HNRNPD/EXOSC8/SERBP1/APEX1/POLR2G/HNRNPR/HNRNPM 10 GO:0045861 negative regulation of proteolysis 19/719 351/18722 0.0845029980811193 0.375869116821297 PTTG1/GAPDH/BIRC5/PBK/RPL11/RPS7/RPL5/PEBP1/PARK7/ANXA2/RPL23/PRDX5/BCL2L12/HSP90AB1/PRDX3/TRIAP1/EIF3H/PIH1D1/TAF9 19 GO:0009308 amine metabolic process 8/719 118/18722 0.0845063063558374 0.375869116821297 LY6E/PARK7/COMT/AKR1B1/SMS/ALDH7A1/PNKD/SRM 8 GO:1903313 positive regulation of mRNA metabolic process 8/719 118/18722 0.0845063063558374 0.375869116821297 CCNB1/PRDX6/HNRNPD/EXOSC8/NCL/POLR2G/RBM3/HNRNPR 8 GO:0090342 regulation of cell aging 5/719 61/18722 0.0845461441992841 0.375869116821297 HMGA1/MIF/YBX1/CDKN2A/EEF1E1 5 GO:0010950 positive regulation of endopeptidase activity 11/719 179/18722 0.084727744972446 0.376242004779605 HMGB1/RPS3/HSPE1/PRELID1/ANP32B/PDCD5/HSPD1/PSMD14/NDUFA13/CYCS/BAX 11 GO:0005513 detection of calcium ion 2/719 13/18722 0.0868471725141142 0.383002994478052 CALM2/CALM1 2 GO:0006000 fructose metabolic process 2/719 13/18722 0.0868471725141142 0.383002994478052 ALDOA/AKR1B1 2 GO:0006264 mitochondrial DNA replication 2/719 13/18722 0.0868471725141142 0.383002994478052 SSBP1/STOML2 2 GO:0042538 hyperosmotic salinity response 2/719 13/18722 0.0868471725141142 0.383002994478052 XRCC6/AKR1B1 2 GO:0044794 positive regulation by host of viral process 2/719 13/18722 0.0868471725141142 0.383002994478052 NUCKS1/CFL1 2 GO:1902947 regulation of tau-protein kinase activity 2/719 13/18722 0.0868471725141142 0.383002994478052 HSP90AB1/HSP90AA1 2 GO:0006473 protein acetylation 12/719 201/18722 0.087445470164413 0.385200297635 PARK7/HAT1/SET/MORF4L2/HINT2/PIH1D1/ACTL6A/TAF9/YEATS4/NAA10/RUVBL1/POLE3 12 GO:1903214 regulation of protein targeting to mitochondrion 4/719 44/18722 0.0875847450612513 0.385372878269506 UBE2L3/PDCD5/UBL5/SAE1 4 GO:1902750 negative regulation of cell cycle G2/M phase transition 5/719 62/18722 0.0892163176103928 0.392103678995448 CDK1/AURKB/CLSPN/CDC6/NAE1 5 GO:0006479 protein methylation 11/719 181/18722 0.0899097498780231 0.394251181128006 SNRPB/SNRPD3/TRMT112/EZH2/PIH1D1/DPY30/LCMT1/FBL/PRMT1/NTMT1/DNMT1 11 GO:0008213 protein alkylation 11/719 181/18722 0.0899097498780231 0.394251181128006 SNRPB/SNRPD3/TRMT112/EZH2/PIH1D1/DPY30/LCMT1/FBL/PRMT1/NTMT1/DNMT1 11 GO:0061640 cytoskeleton-dependent cytokinesis 7/719 100/18722 0.0900961960293629 0.394619288638279 STMN1/NUSAP1/AURKB/CKAP2/ECT2/RHOC/DCTN3 7 GO:0017148 negative regulation of translation 14/719 245/18722 0.0907463162860972 0.395068070254601 TYMS/GAPDH/RPS3/RPL13A/YBX1/DHFR/HNRNPD/EXOSC8/SRP9/NCL/EIF6/POLR2G/HNRNPR/MRPL13 14 GO:0000423 mitophagy 3/719 28/18722 0.0908868725142083 0.395068070254601 SLC25A5/VDAC1/PHB2 3 GO:0007064 mitotic sister chromatid cohesion 3/719 28/18722 0.0908868725142083 0.395068070254601 CDC20/NAA10/SMC3 3 GO:0051503 adenine nucleotide transport 3/719 28/18722 0.0908868725142083 0.395068070254601 SLC25A5/SLC25A6/SLC29A1 3 GO:0062125 regulation of mitochondrial gene expression 3/719 28/18722 0.0908868725142083 0.395068070254601 UQCC2/C1QBP/COA3 3 GO:0044773 mitotic DNA damage checkpoint signaling 6/719 81/18722 0.0910195787833328 0.395068070254601 CDK1/RPL26/CLSPN/RPA2/TRIAP1/CCND1 6 GO:1903533 regulation of protein targeting 6/719 81/18722 0.0910195787833328 0.395068070254601 UBE2L3/PDCD5/UBL5/SAE1/HRAS/ITGB1BP1 6 GO:2001021 negative regulation of response to DNA damage stimulus 6/719 81/18722 0.0910195787833328 0.395068070254601 RPS3/TPT1/MIF/RMI2/TRIAP1/TAF9 6 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 4/719 45/18722 0.0933627933220687 0.404327057693998 PPIA/SOD1/PARK7/PARP1 4 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process 4/719 45/18722 0.0933627933220687 0.404327057693998 SLC25A5/VDAC2/BNIP3/BAX 4 GO:0008584 male gonad development 9/719 141/18722 0.0936286358357843 0.405022750525584 HMGB2/NASP/RRM1/EIF2S2/UBB/NUDT1/MEA1/CCND1/BAX 9 GO:0032233 positive regulation of actin filament bundle assembly 5/719 63/18722 0.0940175499959278 0.40624867282191 S100A10/PFN1/RHOC/ID1/ITGB1BP1 5 GO:0009896 positive regulation of catabolic process 25/719 492/18722 0.0949598591801746 0.409860378748512 HMGB1/SLC25A5/CDC20/PARK7/VDAC1/AURKA/PSMC3/RBX1/SUMO2/HNRNPD/EXOSC8/HSP90AA1/CAV1/PSMC1/BAG2/PSMC5/NDUFA13/POLR2G/PHB2/SUMO1/HNRNPR/DDA1/BNIP3/RAD23A/BAX 25 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic 6/719 82/18722 0.0952029302000945 0.410449363124708 FEN1/RNASEH2A/POP7/TSEN34/RPP30/APEX1 6 GO:0051495 positive regulation of cytoskeleton organization 13/719 226/18722 0.0966222037474851 0.413189805382954 S100A10/RPS3/PFN1/DSTN/ARL2/ARPC1A/ARPC5/RHOC/ARPC5L/PFDN2/HRAS/ID1/ITGB1BP1 13 GO:0046546 development of primary male sexual characteristics 9/719 142/18722 0.0967657763688859 0.413189805382954 HMGB2/NASP/RRM1/EIF2S2/UBB/NUDT1/MEA1/CCND1/BAX 9 GO:2000045 regulation of G1/S transition of mitotic cell cycle 9/719 142/18722 0.0967657763688859 0.413189805382954 RPL26/CDC6/RPA2/EZH2/TRIAP1/APEX1/CCND1/TFDP1/CDK2AP2 9 GO:0031109 microtubule polymerization or depolymerization 8/719 122/18722 0.0978082885263194 0.413189805382954 STMN1/RPS3/TPX2/SKA2/ARL2/TUBG1/CKAP2/MZT1 8 GO:0006734 NADH metabolic process 3/719 29/18722 0.0986171514779456 0.413189805382954 ENO1/MDH1/MDH2 3 GO:0009218 pyrimidine ribonucleotide metabolic process 3/719 29/18722 0.0986171514779456 0.413189805382954 NME1/NME4/UMPS 3 GO:0015868 purine ribonucleotide transport 3/719 29/18722 0.0986171514779456 0.413189805382954 SLC25A5/SLC25A6/SLC29A1 3 GO:0034311 diol metabolic process 3/719 29/18722 0.0986171514779456 0.413189805382954 DHFR/PCBD1/PTS 3 GO:0051654 establishment of mitochondrion localization 3/719 29/18722 0.0986171514779456 0.413189805382954 UBB/HSBP1/UXT 3 GO:0001921 positive regulation of receptor recycling 2/719 14/18722 0.0988289938927421 0.413189805382954 ANXA2/NSG1 2 GO:0006241 CTP biosynthetic process 2/719 14/18722 0.0988289938927421 0.413189805382954 NME1/NME4 2 GO:0006521 regulation of cellular amino acid metabolic process 2/719 14/18722 0.0988289938927421 0.413189805382954 PARK7/COMT 2 GO:0006596 polyamine biosynthetic process 2/719 14/18722 0.0988289938927421 0.413189805382954 SMS/SRM 2 GO:0009159 deoxyribonucleoside monophosphate catabolic process 2/719 14/18722 0.0988289938927421 0.413189805382954 DNPH1/PNP 2 GO:0019321 pentose metabolic process 2/719 14/18722 0.0988289938927421 0.413189805382954 DCXR/NUDT5 2 GO:0031468 nuclear membrane reassembly 2/719 14/18722 0.0988289938927421 0.413189805382954 UBE2I/NSFL1C 2 GO:0035563 positive regulation of chromatin binding 2/719 14/18722 0.0988289938927421 0.413189805382954 GMNN/CDT1 2 GO:0036444 calcium import into the mitochondrion 2/719 14/18722 0.0988289938927421 0.413189805382954 VDAC1/MCUR1 2 GO:0042415 norepinephrine metabolic process 2/719 14/18722 0.0988289938927421 0.413189805382954 LY6E/AKR1B1 2 GO:0043173 nucleotide salvage 2/719 14/18722 0.0988289938927421 0.413189805382954 APRT/ADK 2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 2/719 14/18722 0.0988289938927421 0.413189805382954 RPL26/EEF1E1 2 GO:0043558 regulation of translational initiation in response to stress 2/719 14/18722 0.0988289938927421 0.413189805382954 NPM1/PPP1CA 2 GO:0043922 negative regulation by host of viral transcription 2/719 14/18722 0.0988289938927421 0.413189805382954 NUCKS1/PSMC3 2 GO:0045472 response to ether 2/719 14/18722 0.0988289938927421 0.413189805382954 HNRNPD/CDK4 2 GO:0071236 cellular response to antibiotic 2/719 14/18722 0.0988289938927421 0.413189805382954 RPL23/EZH2 2 GO:0071481 cellular response to X-ray 2/719 14/18722 0.0988289938927421 0.413189805382954 NUCKS1/XRCC6 2 GO:1900037 regulation of cellular response to hypoxia 2/719 14/18722 0.0988289938927421 0.413189805382954 ENO1/CHCHD2 2 GO:0032507 maintenance of protein location in cell 5/719 64/18722 0.0989481112963599 0.413189805382954 TXN/PARK7/ARL2/CAV1/SKP1 5 GO:0006383 transcription by RNA polymerase III 4/719 46/18722 0.0993165620632708 0.413189805382954 POLR2L/PRDX5/POLR3K/POLR2K 4 GO:0042398 cellular modified amino acid biosynthetic process 4/719 46/18722 0.0993165620632708 0.413189805382954 DHFR/PARK7/ALDH7A1/ATIC 4 GO:0044818 mitotic G2/M transition checkpoint 4/719 46/18722 0.0993165620632708 0.413189805382954 CDK1/CLSPN/CDC6/NAE1 4 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 4/719 46/18722 0.0993165620632708 0.413189805382954 CDC6/APEX1/CCND1/TFDP1 4 GO:0046785 microtubule polymerization 6/719 83/18722 0.0994875193740255 0.413189805382954 STMN1/RPS3/TPX2/ARL2/TUBG1/MZT1 6 GO:0048678 response to axon injury 6/719 83/18722 0.0994875193740255 0.413189805382954 CDK1/SOD1/DHFR/TXN2/BNIP3/BAX 6 GO:0032386 regulation of intracellular transport 18/719 337/18722 0.100108644356207 0.415321423245038 CDK1/RAN/TXN/PARK7/ANXA2/ANP32B/HSP90AB1/UBE2L3/YWHAE/PDCD5/UBL5/NUTF2/ECT2/SNX3/SAE1/SUMO1/HRAS/ITGB1BP1 18 GO:0046718 viral entry into host cell 9/719 144/18722 0.103220612801788 0.427771107951438 CDK1/RPSA/SIVA1/LY6E/DYNLT1/CAV1/VAMP8/SNX3/PHB 9 GO:0098586 cellular response to virus 6/719 84/18722 0.103872356432761 0.428719002044423 C1QBP/HSP90AA1/EIF5A/PHB/PHB2/BAX 6 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 6/719 84/18722 0.103872356432761 0.428719002044423 RPL26/RPA2/EZH2/TRIAP1/CCND1/CDK2AP2 6 GO:0048524 positive regulation of viral process 5/719 65/18722 0.104006116340127 0.428719002044423 PPIA/TOP2A/KPNA2/PPIH/RAD23A 5 GO:0051310 metaphase plate congression 5/719 65/18722 0.104006116340127 0.428719002044423 AURKB/CDT1/NUF2/CCNB1/NUDC 5 GO:0070936 protein K48-linked ubiquitination 5/719 65/18722 0.104006116340127 0.428719002044423 UBE2C/UBE2T/PPIA/RBX1/SKP1 5 GO:0006790 sulfur compound metabolic process 18/719 339/18722 0.104258527904638 0.429299820783803 GSTO1/GSTP1/SOD1/PARK7/COMT/MPC2/GPX4/TSTD1/NUDT8/NFU1/ADI1/SMS/GLO1/ETHE1/GLRX3/NUBP2/ISCU/SLC25A1 18 GO:0034249 negative regulation of cellular amide metabolic process 15/719 273/18722 0.105236197185133 0.432862563208078 TYMS/GAPDH/RPS3/RPL13A/YBX1/DHFR/HNRNPD/EXOSC8/SRP9/NCL/EIF6/POLR2G/HNRNPR/MRPL13/PIN1 15 GO:0046677 response to antibiotic 4/719 47/18722 0.105441870824912 0.433245680550599 SOD1/RPL23/HSP90AA1/EZH2 4 GO:0000132 establishment of mitotic spindle orientation 3/719 30/18722 0.106602017119872 0.435687649587585 MAD2L1/DYNLT1/NSFL1C 3 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 3/719 30/18722 0.106602017119872 0.435687649587585 CALM2/GSTO1/CALM1 3 GO:0015865 purine nucleotide transport 3/719 30/18722 0.106602017119872 0.435687649587585 SLC25A5/SLC25A6/SLC29A1 3 GO:0031365 N-terminal protein amino acid modification 3/719 30/18722 0.106602017119872 0.435687649587585 NTMT1/NAA10/METAP2 3 GO:0036296 response to increased oxygen levels 3/719 30/18722 0.106602017119872 0.435687649587585 CAV1/CDK4/BNIP3 3 GO:0061013 regulation of mRNA catabolic process 10/719 166/18722 0.106982917850635 0.436780735657417 NPM1/CARHSP1/YBX1/HNRNPD/EXOSC8/SERBP1/APEX1/POLR2G/HNRNPR/HNRNPM 10 GO:0032092 positive regulation of protein binding 6/719 85/18722 0.108356355476052 0.44191945824449 RAN/RPL11/ANXA2/HSP90AB1/CAV1/PIN1 6 GO:0006303 double-strand break repair via nonhomologous end joining 5/719 66/18722 0.109189531866951 0.44242368957812 HMGB2/HMGB1/DEK/XRCC6/PSMD14 5 GO:0006575 cellular modified amino acid metabolic process 11/719 188/18722 0.109531473206102 0.44242368957812 TYMS/GSTO1/GSTP1/SOD1/DHFR/PARK7/GPX4/ALDH7A1/GLO1/ATIC/ETHE1 11 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2/719 15/18722 0.111237956236785 0.44242368957812 RPL35/RPL7 2 GO:0002070 epithelial cell maturation 2/719 15/18722 0.111237956236785 0.44242368957812 TYMS/AKR1B1 2 GO:0002679 respiratory burst involved in defense response 2/719 15/18722 0.111237956236785 0.44242368957812 PRDX2/RPS19 2 GO:0003356 regulation of cilium beat frequency 2/719 15/18722 0.111237956236785 0.44242368957812 CFAP20/MKKS 2 GO:0006098 pentose-phosphate shunt 2/719 15/18722 0.111237956236785 0.44242368957812 PGAM1/TALDO1 2 GO:0009083 branched-chain amino acid catabolic process 2/719 15/18722 0.111237956236785 0.44242368957812 ECHS1/HSD17B10 2 GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process 2/719 15/18722 0.111237956236785 0.44242368957812 NME1/NME4 2 GO:0010273 detoxification of copper ion 2/719 15/18722 0.111237956236785 0.44242368957812 MT2A/PARK7 2 GO:0023035 CD40 signaling pathway 2/719 15/18722 0.111237956236785 0.44242368957812 PHB/PHB2 2 GO:0042182 ketone catabolic process 2/719 15/18722 0.111237956236785 0.44242368957812 PARK7/PNKD 2 GO:0044793 negative regulation by host of viral process 2/719 15/18722 0.111237956236785 0.44242368957812 NUCKS1/PSMC3 2 GO:0045842 positive regulation of mitotic metaphase/anaphase transition 2/719 15/18722 0.111237956236785 0.44242368957812 ANAPC11/CDT1 2 GO:0048308 organelle inheritance 2/719 15/18722 0.111237956236785 0.44242368957812 CDK1/VRK1 2 GO:0048313 Golgi inheritance 2/719 15/18722 0.111237956236785 0.44242368957812 CDK1/VRK1 2 GO:0055012 ventricular cardiac muscle cell differentiation 2/719 15/18722 0.111237956236785 0.44242368957812 CDK1/CCNB1 2 GO:0071474 cellular hyperosmotic response 2/719 15/18722 0.111237956236785 0.44242368957812 XRCC6/AKR1B1 2 GO:0140374 antiviral innate immune response 2/719 15/18722 0.111237956236785 0.44242368957812 PHB/PHB2 2 GO:1900029 positive regulation of ruffle assembly 2/719 15/18722 0.111237956236785 0.44242368957812 PFN1/HRAS 2 GO:1901836 regulation of transcription of nucleolar large rRNA by RNA polymerase I 2/719 15/18722 0.111237956236785 0.44242368957812 NCL/PIH1D1 2 GO:1901970 positive regulation of mitotic sister chromatid separation 2/719 15/18722 0.111237956236785 0.44242368957812 ANAPC11/CDT1 2 GO:1905168 positive regulation of double-strand break repair via homologous recombination 2/719 15/18722 0.111237956236785 0.44242368957812 RAD51AP1/PARP1 2 GO:1990169 stress response to copper ion 2/719 15/18722 0.111237956236785 0.44242368957812 MT2A/PARK7 2 GO:0009895 negative regulation of catabolic process 17/719 320/18722 0.111513910416876 0.443063524360138 MAD2L1/PBK/RPL11/RPS7/RPL5/YBX1/PARK7/ANXA2/RPL23/SLIRP/HSP90AB1/HNRNPD/EIF3H/SNX3/PHB/TAF9/PIN1 17 GO:0045005 DNA-dependent DNA replication maintenance of fidelity 4/719 48/18722 0.111734308006215 0.443481531777244 PCNA/RAD51/NUCKS1/ALYREF 4 GO:1902806 regulation of cell cycle G1/S phase transition 10/719 168/18722 0.113329135352933 0.449348270966829 RPL26/CDC6/RPA2/EZH2/TRIAP1/APEX1/CCND1/PHB2/TFDP1/CDK2AP2 10 GO:0001824 blastocyst development 7/719 106/18722 0.113482223087536 0.449492344533964 NASP/RRM2/RPL13/ASF1B/SF3B6/ACTL6A/NDUFA2 7 GO:0033238 regulation of cellular amine metabolic process 3/719 31/18722 0.114829521520872 0.452964813376389 PARK7/COMT/PNKD 3 GO:1900027 regulation of ruffle assembly 3/719 31/18722 0.114829521520872 0.452964813376389 PFN1/CAV1/HRAS 3 GO:1901797 negative regulation of signal transduction by p53 class mediator 3/719 31/18722 0.114829521520872 0.452964813376389 MIF/TRIAP1/TAF9 3 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 3/719 31/18722 0.114829521520872 0.452964813376389 HMGB2/PARK7/FAIM 3 GO:0051224 negative regulation of protein transport 8/719 127/18722 0.115999803457561 0.456977443284705 TXN/PARK7/IDH2/ENY2/HADH/SNX3/SUMO1/ITGB1BP1 8 GO:0009615 response to virus 19/719 367/18722 0.116084140138296 0.456977443284705 STMN1/ENO1/TPT1/RPS15A/HMGA1/CFL1/BANF1/CCT5/PSMA2/C1QBP/HSP90AA1/POLR3K/EIF5A/VAMP8/PHB/PHB2/AP1S1/BNIP3/BAX 19 GO:0051384 response to glucocorticoid 9/719 148/18722 0.116845420251487 0.459035579559413 TYMS/PCNA/HMGB1/GSTP1/CALM1/ANXA3/UBE2L3/HSPD1/CCND1 9 GO:2001056 positive regulation of cysteine-type endopeptidase activity 9/719 148/18722 0.116845420251487 0.459035579559413 HMGB1/RPS3/HSPE1/ANP32B/PDCD5/HSPD1/NDUFA13/CYCS/BAX 9 GO:0051341 regulation of oxidoreductase activity 7/719 107/18722 0.117663425382391 0.461021900888857 CALM1/DHFR/PARK7/NDUFA4/COX17/CAV1/PHB2 7 GO:0000959 mitochondrial RNA metabolic process 4/719 49/18722 0.118189250955143 0.461021900888857 SLIRP/MRPL12/HSD17B10/TFAM 4 GO:0006376 mRNA splice site selection 4/719 49/18722 0.118189250955143 0.461021900888857 SNRPC/PSIP1/SRSF9/SF3A3 4 GO:0006692 prostanoid metabolic process 4/719 49/18722 0.118189250955143 0.461021900888857 GSTP1/MIF/PTGES3/AKR1B1 4 GO:0006693 prostaglandin metabolic process 4/719 49/18722 0.118189250955143 0.461021900888857 GSTP1/MIF/PTGES3/AKR1B1 4 GO:0014075 response to amine 4/719 49/18722 0.118189250955143 0.461021900888857 CDK1/CALM1/SOD1/NME1 4 GO:0030857 negative regulation of epithelial cell differentiation 4/719 49/18722 0.118189250955143 0.461021900888857 EZH2/CAV1/CCND1/ID1 4 GO:0035303 regulation of dephosphorylation 8/719 128/18722 0.119842490003454 0.466370192128452 CALM2/PPIA/CALM1/HSP90AB1/YWHAE/CSNK2B/PIN1/ENSA 8 GO:0043487 regulation of RNA stability 10/719 170/18722 0.119882992600068 0.466370192128452 NPM1/CARHSP1/YBX1/HNRNPD/EXOSC8/SERBP1/APEX1/POLR2G/HNRNPR/HNRNPM 10 GO:0031640 killing of cells of other organism 5/719 68/18722 0.119923763690173 0.466370192128452 GAPDH/HMGN2/RPS19/RPL30/ROMO1 5 GO:0005996 monosaccharide metabolic process 14/719 257/18722 0.120398180545877 0.467742679214558 HMGB1/GAPDH/GSTO1/ENO1/TPI1/ALDOA/PPP1CA/PGP/PHLDA2/DCXR/AKR1B1/LCMT1/NUDT5/SLC25A1 14 GO:0031110 regulation of microtubule polymerization or depolymerization 6/719 88/18722 0.122391086966366 0.469971665546496 STMN1/RPS3/TPX2/SKA2/ARL2/CKAP2 6 GO:0006335 DNA replication-dependent nucleosome assembly 3/719 32/18722 0.123287531257897 0.469971665546496 NASP/ASF1B/HAT1 3 GO:0008156 negative regulation of DNA replication 3/719 32/18722 0.123287531257897 0.469971665546496 GMNN/CDC6/S100A11 3 GO:0010644 cell communication by electrical coupling 3/719 32/18722 0.123287531257897 0.469971665546496 CALM2/CALM1/CAV1 3 GO:0034723 DNA replication-dependent nucleosome organization 3/719 32/18722 0.123287531257897 0.469971665546496 NASP/ASF1B/HAT1 3 GO:0005980 glycogen catabolic process 2/719 16/18722 0.124023691479283 0.469971665546496 HMGB1/PPP1CA 2 GO:0006544 glycine metabolic process 2/719 16/18722 0.124023691479283 0.469971665546496 GCSH/DHFR 2 GO:0006555 methionine metabolic process 2/719 16/18722 0.124023691479283 0.469971665546496 ADI1/SMS 2 GO:0006740 NADPH regeneration 2/719 16/18722 0.124023691479283 0.469971665546496 PGAM1/TALDO1 2 GO:0009415 response to water 2/719 16/18722 0.124023691479283 0.469971665546496 KRT8/AKR1B1 2 GO:0014819 regulation of skeletal muscle contraction 2/719 16/18722 0.124023691479283 0.469971665546496 GSTO1/C12orf57 2 GO:0035067 negative regulation of histone acetylation 2/719 16/18722 0.124023691479283 0.469971665546496 SET/PIH1D1 2 GO:0035970 peptidyl-threonine dephosphorylation 2/719 16/18722 0.124023691479283 0.469971665546496 PPP1CA/PPM1G 2 GO:0046036 CTP metabolic process 2/719 16/18722 0.124023691479283 0.469971665546496 NME1/NME4 2 GO:0046037 GMP metabolic process 2/719 16/18722 0.124023691479283 0.469971665546496 IMPDH2/GMPS 2 GO:0051014 actin filament severing 2/719 16/18722 0.124023691479283 0.469971665546496 CFL1/DSTN 2 GO:0061684 chaperone-mediated autophagy 2/719 16/18722 0.124023691479283 0.469971665546496 EEF1A1/HSP90AA1 2 GO:0070230 positive regulation of lymphocyte apoptotic process 2/719 16/18722 0.124023691479283 0.469971665546496 PRELID1/BAX 2 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process 2/719 16/18722 0.124023691479283 0.469971665546496 TPRKB/HSD17B10 2 GO:0071732 cellular response to nitric oxide 2/719 16/18722 0.124023691479283 0.469971665546496 CCNA2/HNRNPD 2 GO:0097284 hepatocyte apoptotic process 2/719 16/18722 0.124023691479283 0.469971665546496 KRT8/KRT18 2 GO:0097428 protein maturation by iron-sulfur cluster transfer 2/719 16/18722 0.124023691479283 0.469971665546496 NFU1/GLRX3 2 GO:1902101 positive regulation of metaphase/anaphase transition of cell cycle 2/719 16/18722 0.124023691479283 0.469971665546496 ANAPC11/CDT1 2 GO:1902570 protein localization to nucleolus 2/719 16/18722 0.124023691479283 0.469971665546496 RAN/NPM1 2 GO:2000001 regulation of DNA damage checkpoint 2/719 16/18722 0.124023691479283 0.469971665546496 RPA2/RNASEH2B 2 GO:0045814 negative regulation of gene expression, epigenetic 4/719 50/18722 0.124801885575655 0.47199141401402 HELLS/EZH2/DNMT1/POLE3 4 GO:1903747 regulation of establishment of protein localization to mitochondrion 4/719 50/18722 0.124801885575655 0.47199141401402 UBE2L3/PDCD5/UBL5/SAE1 4 GO:0006470 protein dephosphorylation 15/719 281/18722 0.125224840367249 0.473123285218605 CALM2/PPIA/CDKN3/PHPT1/CALM1/HSP90AB1/YWHAE/PPP1CA/PGP/CSNK2B/PPM1G/ACP1/PIN1/PPP4C/ENSA 15 GO:0006368 transcription elongation from RNA polymerase II promoter 5/719 69/18722 0.125469837456674 0.473123285218605 CDCA4/ENY2/EZH2/POLR2I/SUPT16H 5 GO:0070192 chromosome organization involved in meiotic cell cycle 5/719 69/18722 0.125469837456674 0.473123285218605 RAD51/CCNE1/RAD51C/SMC2/SMC4 5 GO:0031334 positive regulation of protein-containing complex assembly 13/719 237/18722 0.126066120957388 0.474906620044956 RPS3/PFN1/CDT1/PARK7/ARL2/HSP90AA1/ARPC1A/ARPC5/PIH1D1/RHOC/ARPC5L/SUMO1/BAX 13 GO:0042770 signal transduction in response to DNA damage 10/719 172/18722 0.126642220699132 0.476610508007486 CDK1/NPM1/RPL26/MIF/CLSPN/RPA2/TRIAP1/EEF1E1/CCND1/RNASEH2B 10 GO:0044409 entry into host 9/719 151/18722 0.127679100743061 0.479758208095066 CDK1/RPSA/SIVA1/LY6E/DYNLT1/CAV1/VAMP8/SNX3/PHB 9 GO:0007098 centrosome cycle 8/719 130/18722 0.127727834622712 0.479758208095066 CDK1/RANBP1/NPM1/AURKA/HAUS1/ARL2/UXT/NSFL1C 8 GO:0019079 viral genome replication 8/719 131/18722 0.131769194665803 0.492784267318619 PPIA/TOP2A/DEK/NUCKS1/BANF1/PHB/PPIH/RAD23A 8 GO:1904950 negative regulation of establishment of protein localization 8/719 131/18722 0.131769194665803 0.492784267318619 TXN/PARK7/IDH2/ENY2/HADH/SNX3/SUMO1/ITGB1BP1 8 GO:0046685 response to arsenic-containing substance 3/719 33/18722 0.131963786910519 0.492784267318619 GSTO1/HNRNPA1/PPIF 3 GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 3/719 33/18722 0.131963786910519 0.492784267318619 HMGB1/SUB1/CDK4 3 GO:0061842 microtubule organizing center localization 3/719 33/18722 0.131963786910519 0.492784267318619 MAD2L1/AURKA/ARPC5 3 GO:0071763 nuclear membrane organization 3/719 33/18722 0.131963786910519 0.492784267318619 VRK1/UBE2I/NSFL1C 3 GO:0000281 mitotic cytokinesis 5/719 71/18722 0.13690713897065 0.506781809774792 STMN1/NUSAP1/CKAP2/ECT2/RHOC 5 GO:0006390 mitochondrial transcription 2/719 17/18722 0.137139060738476 0.506781809774792 MRPL12/TFAM 2 GO:0007096 regulation of exit from mitosis 2/719 17/18722 0.137139060738476 0.506781809774792 UBE2C/PHB2 2 GO:0008334 histone mRNA metabolic process 2/719 17/18722 0.137139060738476 0.506781809774792 SLBP/SSB 2 GO:0009251 glucan catabolic process 2/719 17/18722 0.137139060738476 0.506781809774792 HMGB1/PPP1CA 2 GO:0015867 ATP transport 2/719 17/18722 0.137139060738476 0.506781809774792 SLC25A5/SLC25A6 2 GO:0032048 cardiolipin metabolic process 2/719 17/18722 0.137139060738476 0.506781809774792 STOML2/PHB2 2 GO:0033151 V(D)J recombination 2/719 17/18722 0.137139060738476 0.506781809774792 HMGB2/HMGB1 2 GO:0046827 positive regulation of protein export from nucleus 2/719 17/18722 0.137139060738476 0.506781809774792 ANP32B/YWHAE 2 GO:0090399 replicative senescence 2/719 17/18722 0.137139060738476 0.506781809774792 ROMO1/CDKN2A 2 GO:0052126 movement in host environment 10/719 175/18722 0.13716016773645 0.506781809774792 CDK1/PPIA/RPSA/SIVA1/LY6E/DYNLT1/CAV1/VAMP8/SNX3/PHB 10 GO:0000096 sulfur amino acid metabolic process 3/719 34/18722 0.140845957229562 0.517420739822343 COMT/ADI1/SMS 3 GO:0010922 positive regulation of phosphatase activity 3/719 34/18722 0.140845957229562 0.517420739822343 CALM2/CALM1/HSP90AB1 3 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 3/719 34/18722 0.140845957229562 0.517420739822343 CALM2/GSTO1/CALM1 3 GO:0032743 positive regulation of interleukin-2 production 3/719 34/18722 0.140845957229562 0.517420739822343 RPS3/STOML2/PNP 3 GO:0032770 positive regulation of monooxygenase activity 3/719 34/18722 0.140845957229562 0.517420739822343 CALM1/DHFR/PARK7 3 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus 3/719 34/18722 0.140845957229562 0.517420739822343 C1QBP/PHB/PHB2 3 GO:1903312 negative regulation of mRNA metabolic process 6/719 92/18722 0.142410891657884 0.522671051365922 NPM1/YBX1/HNRNPD/SAP18/C1QBP/SRSF9 6 GO:0005977 glycogen metabolic process 5/719 72/18722 0.142792930354096 0.523075910431274 HMGB1/PTGES3/PPP1CA/PHLDA2/UGP2 5 GO:0030330 DNA damage response, signal transduction by p53 class mediator 5/719 72/18722 0.142792930354096 0.523075910431274 NPM1/RPL26/MIF/TRIAP1/EEF1E1 5 GO:0043543 protein acylation 13/719 243/18722 0.144051355866701 0.527184144569202 PARK7/HAT1/SET/MORF4L2/HINT2/PIH1D1/ACTL6A/TAF9/YEATS4/NAA10/RUVBL1/ZDHHC12/POLE3 13 GO:0032784 regulation of DNA-templated transcription, elongation 4/719 53/18722 0.145535323651912 0.531100470198919 HMGN1/EZH2/ALYREF/SUPT16H 4 GO:1903202 negative regulation of oxidative stress-induced cell death 4/719 53/18722 0.145535323651912 0.531100470198919 PPIA/PAGE4/TXN/PARK7 4 GO:2000772 regulation of cellular senescence 4/719 53/18722 0.145535323651912 0.531100470198919 HMGA1/YBX1/CDKN2A/EEF1E1 4 GO:0045185 maintenance of protein location 6/719 93/18722 0.147638573646259 0.53615071914133 TXN/PARK7/ARL2/CAV1/SKP1/MDFI 6 GO:1902807 negative regulation of cell cycle G1/S phase transition 6/719 93/18722 0.147638573646259 0.53615071914133 RPL26/RPA2/EZH2/TRIAP1/CCND1/CDK2AP2 6 GO:0006073 cellular glucan metabolic process 5/719 73/18722 0.148786357184446 0.53615071914133 HMGB1/PTGES3/PPP1CA/PHLDA2/UGP2 5 GO:0044042 glucan metabolic process 5/719 73/18722 0.148786357184446 0.53615071914133 HMGB1/PTGES3/PPP1CA/PHLDA2/UGP2 5 GO:0000460 maturation of 5.8S rRNA 3/719 35/18722 0.149921688328916 0.53615071914133 EXOSC8/EIF6/MPHOSPH6 3 GO:0000731 DNA synthesis involved in DNA repair 3/719 35/18722 0.149921688328916 0.53615071914133 PCNA/RFC3/POLD3 3 GO:0007020 microtubule nucleation 3/719 35/18722 0.149921688328916 0.53615071914133 TPX2/TUBG1/MZT1 3 GO:0009119 ribonucleoside metabolic process 3/719 35/18722 0.149921688328916 0.53615071914133 PNP/APRT/ADK 3 GO:0021955 central nervous system neuron axonogenesis 3/719 35/18722 0.149921688328916 0.53615071914133 HSP90AB1/HSP90AA1/C12orf57 3 GO:0043243 positive regulation of protein-containing complex disassembly 3/719 35/18722 0.149921688328916 0.53615071914133 DSTN/EIF5A/BNIP3 3 GO:1903514 release of sequestered calcium ion into cytosol by endoplasmic reticulum 3/719 35/18722 0.149921688328916 0.53615071914133 CALM2/GSTO1/CALM1 3 GO:0001522 pseudouridine synthesis 2/719 18/18722 0.150539981140721 0.53615071914133 NHP2/NOP10 2 GO:0006595 polyamine metabolic process 2/719 18/18722 0.150539981140721 0.53615071914133 SMS/SRM 2 GO:0009125 nucleoside monophosphate catabolic process 2/719 18/18722 0.150539981140721 0.53615071914133 DNPH1/PNP 2 GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process 2/719 18/18722 0.150539981140721 0.53615071914133 NME1/NME4 2 GO:0032095 regulation of response to food 2/719 18/18722 0.150539981140721 0.53615071914133 NENF/MKKS 2 GO:0042790 nucleolar large rRNA transcription by RNA polymerase I 2/719 18/18722 0.150539981140721 0.53615071914133 NCL/PIH1D1 2 GO:0044247 cellular polysaccharide catabolic process 2/719 18/18722 0.150539981140721 0.53615071914133 HMGB1/PPP1CA 2 GO:0051782 negative regulation of cell division 2/719 18/18722 0.150539981140721 0.53615071914133 AURKB/ORC6 2 GO:0060749 mammary gland alveolus development 2/719 18/18722 0.150539981140721 0.53615071914133 CCND1/PHB2 2 GO:0061377 mammary gland lobule development 2/719 18/18722 0.150539981140721 0.53615071914133 CCND1/PHB2 2 GO:0061687 detoxification of inorganic compound 2/719 18/18722 0.150539981140721 0.53615071914133 MT2A/PARK7 2 GO:1902074 response to salt 2/719 18/18722 0.150539981140721 0.53615071914133 HNRNPA1/HNRNPD 2 GO:1902170 cellular response to reactive nitrogen species 2/719 18/18722 0.150539981140721 0.53615071914133 CCNA2/HNRNPD 2 GO:1903209 positive regulation of oxidative stress-induced cell death 2/719 18/18722 0.150539981140721 0.53615071914133 SOD1/PARK7 2 GO:1905820 positive regulation of chromosome separation 2/719 18/18722 0.150539981140721 0.53615071914133 ANAPC11/CDT1 2 GO:0051017 actin filament bundle assembly 9/719 157/18722 0.150874050714789 0.536843895796617 STMN1/S100A10/PFN1/PDLIM1/ACTG1/RHOC/MKKS/ID1/ITGB1BP1 9 GO:0006399 tRNA metabolic process 10/719 179/18722 0.151874598714903 0.539905083150857 TRMT112/EXOSC8/TPRKB/POP7/POLR3K/TSEN34/LSM6/RPP30/SSB/HSD17B10 10 GO:0019080 viral gene expression 6/719 94/18722 0.152951832175755 0.543232983281048 NUCKS1/PSMC3/EIF3F/SSB/EIF3L/MCTS1 6 GO:0000077 DNA damage checkpoint signaling 7/719 115/18722 0.153872661259432 0.545999765759276 CDK1/RPL26/CLSPN/RPA2/TRIAP1/CCND1/RNASEH2B 7 GO:0006801 superoxide metabolic process 5/719 74/18722 0.154884460936966 0.549083954518709 PRDX2/GSTP1/PRDX1/SOD1/DHFR 5 GO:0030879 mammary gland development 8/719 137/18722 0.157351697498885 0.557317419844258 NME1/CAV1/CCND1/PHB2/APRT/SLC29A1/UMPS/BAX 8 GO:0034284 response to monosaccharide 12/719 225/18722 0.158179571287298 0.559669219840404 LDHA/GSTP1/PHPT1/DYNLL1/NME1/KRT18/MPC2/ENY2/PIH1D1/TXN2/SLC29A1/ENSA 12 GO:0036473 cell death in response to oxidative stress 6/719 95/18722 0.158348794400228 0.559669219840404 PPIA/PAGE4/TXN/SOD1/PARK7/PARP1 6 GO:0031123 RNA 3'-end processing 7/719 116/18722 0.158727337312029 0.559669219840404 CCNB1/SLBP/EXOSC8/POLR3K/SSB/FBL/HSD17B10 7 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 3/719 36/18722 0.159178648240323 0.559669219840404 PHPT1/DYNLL1/MPC2 3 GO:0044743 protein transmembrane import into intracellular organelle 3/719 36/18722 0.159178648240323 0.559669219840404 HSPD1/ROMO1/TOMM40 3 GO:0045652 regulation of megakaryocyte differentiation 3/719 36/18722 0.159178648240323 0.559669219840404 HMGB2/EIF6/PRMT1 3 GO:0070873 regulation of glycogen metabolic process 3/719 36/18722 0.159178648240323 0.559669219840404 HMGB1/PPP1CA/PHLDA2 3 GO:0090322 regulation of superoxide metabolic process 3/719 36/18722 0.159178648240323 0.559669219840404 GSTP1/SOD1/DHFR 3 GO:0043414 macromolecule methylation 16/719 316/18722 0.159491155530105 0.560256340137688 SNRPB/SNRPD3/TRMT112/HELLS/EZH2/PIH1D1/DPY30/LCMT1/METTL5/FBL/MIS18A/PRMT1/PARP1/NTMT1/DNMT1/HSD17B10 16 GO:0006360 transcription by RNA polymerase I 4/719 55/18722 0.160050895839392 0.561710071997866 POLR2L/NCL/PIH1D1/POLR2K 4 GO:0071241 cellular response to inorganic substance 12/719 226/18722 0.161631386289531 0.566740288902271 MT2A/RAD51/CCNA2/CCNB1/SOD1/CACYBP/HNRNPD/ECT2/PPIF/PARP1/SUMO1/BNIP3 12 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic 2/719 19/18722 0.164185261153029 0.568958825777824 EXOSC8/POLR2G 2 GO:0002902 regulation of B cell apoptotic process 2/719 19/18722 0.164185261153029 0.568958825777824 AURKB/BAX 2 GO:0006071 glycerol metabolic process 2/719 19/18722 0.164185261153029 0.568958825777824 TPI1/PGP 2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 2/719 19/18722 0.164185261153029 0.568958825777824 RPL26/TRIAP1 2 GO:0009081 branched-chain amino acid metabolic process 2/719 19/18722 0.164185261153029 0.568958825777824 ECHS1/HSD17B10 2 GO:0030011 maintenance of cell polarity 2/719 19/18722 0.164185261153029 0.568958825777824 PDLIM1/ARPC5 2 GO:0044320 cellular response to leptin stimulus 2/719 19/18722 0.164185261153029 0.568958825777824 CCNA2/MKKS 2 GO:0044827 modulation by host of viral genome replication 2/719 19/18722 0.164185261153029 0.568958825777824 NUCKS1/PHB 2 GO:0045019 negative regulation of nitric oxide biosynthetic process 2/719 19/18722 0.164185261153029 0.568958825777824 DYNLL1/CAV1 2 GO:0046716 muscle cell cellular homeostasis 2/719 19/18722 0.164185261153029 0.568958825777824 ALDOA/SOD1 2 GO:0070262 peptidyl-serine dephosphorylation 2/719 19/18722 0.164185261153029 0.568958825777824 YWHAE/PPP1CA 2 GO:0097501 stress response to metal ion 2/719 19/18722 0.164185261153029 0.568958825777824 MT2A/PARK7 2 GO:1904406 negative regulation of nitric oxide metabolic process 2/719 19/18722 0.164185261153029 0.568958825777824 DYNLL1/CAV1 2 GO:0032259 methylation 18/719 364/18722 0.164942572127655 0.571069157096648 TYMS/SNRPB/SNRPD3/TRMT112/COMT/HELLS/EZH2/PIH1D1/DPY30/LCMT1/METTL5/FBL/MIS18A/PRMT1/PARP1/NTMT1/DNMT1/HSD17B10 18 GO:0006305 DNA alkylation 5/719 76/18722 0.167382455418865 0.57648986103963 HELLS/EZH2/MIS18A/PARP1/DNMT1 5 GO:0006306 DNA methylation 5/719 76/18722 0.167382455418865 0.57648986103963 HELLS/EZH2/MIS18A/PARP1/DNMT1 5 GO:0006809 nitric oxide biosynthetic process 5/719 76/18722 0.167382455418865 0.57648986103963 DYNLL1/HSP90AB1/HSP90AA1/CAV1/CYB5B 5 GO:2000379 positive regulation of reactive oxygen species metabolic process 5/719 76/18722 0.167382455418865 0.57648986103963 GSTP1/SOD1/PARK7/DCXR/ROMO1 5 GO:0061572 actin filament bundle organization 9/719 161/18722 0.167417521234262 0.57648986103963 STMN1/S100A10/PFN1/PDLIM1/ACTG1/RHOC/MKKS/ID1/ITGB1BP1 9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 3/719 37/18722 0.168604567150811 0.57648986103963 MAGOH/RBM8A/MAGOHB 3 GO:0006862 nucleotide transport 3/719 37/18722 0.168604567150811 0.57648986103963 SLC25A5/SLC25A6/SLC29A1 3 GO:0033120 positive regulation of RNA splicing 3/719 37/18722 0.168604567150811 0.57648986103963 PRDX6/NCL/RBM3 3 GO:0034260 negative regulation of GTPase activity 3/719 37/18722 0.168604567150811 0.57648986103963 ARL2/MKKS/HRAS 3 GO:0042401 cellular biogenic amine biosynthetic process 3/719 37/18722 0.168604567150811 0.57648986103963 PARK7/SMS/SRM 3 GO:0043029 T cell homeostasis 3/719 37/18722 0.168604567150811 0.57648986103963 RPS6/CCNB2/BAX 3 GO:0043687 post-translational protein modification 3/719 37/18722 0.168604567150811 0.57648986103963 RBX1/FN3KRP/LCMT1 3 GO:0051294 establishment of spindle orientation 3/719 37/18722 0.168604567150811 0.57648986103963 MAD2L1/DYNLT1/NSFL1C 3 GO:0072529 pyrimidine-containing compound catabolic process 3/719 37/18722 0.168604567150811 0.57648986103963 DUT/DCTPP1/UNG 3 GO:0031333 negative regulation of protein-containing complex assembly 8/719 140/18722 0.170961836468789 0.58403111837164 STMN1/HMGB1/PFN1/RPL13A/PARK7/VDAC2/LCMT1/MKKS 8 GO:0009416 response to light stimulus 16/719 320/18722 0.171278863618291 0.584595412172357 PCNA/PBK/NPM1/AURKB/RPL26/FEN1/PPP1CA/HMGN1/DYNLRB1/TRIAP1/COPS3/CCND1/POLD3/PARP1/BAX/USP1 16 GO:0002200 somatic diversification of immune receptors 5/719 77/18722 0.173776040256058 0.592593228508258 HMGB2/HMGB1/UNG/CTNNBL1/HSPD1 5 GO:0006754 ATP biosynthetic process 4/719 57/18722 0.175069656864197 0.595948876151332 ENO1/ALDOA/STOML2/PARP1 4 GO:0051289 protein homotetramerization 4/719 57/18722 0.175069656864197 0.595948876151332 TK1/ALDOA/SSBP1/HSD17B10 4 GO:0016571 histone methylation 8/719 141/18722 0.175613457559497 0.596540002999995 TRMT112/EZH2/PIH1D1/DPY30/FBL/PRMT1/NTMT1/DNMT1 8 GO:0009743 response to carbohydrate 13/719 253/18722 0.176900323502135 0.596540002999995 LDHA/GSTP1/CDT1/PHPT1/DYNLL1/NME1/KRT18/MPC2/ENY2/PIH1D1/TXN2/SLC29A1/ENSA 13 GO:0000272 polysaccharide catabolic process 2/719 20/18722 0.178036444028403 0.596540002999995 HMGB1/PPP1CA 2 GO:0002834 regulation of response to tumor cell 2/719 20/18722 0.178036444028403 0.596540002999995 HMGB1/HSPD1 2 GO:0002837 regulation of immune response to tumor cell 2/719 20/18722 0.178036444028403 0.596540002999995 HMGB1/HSPD1 2 GO:0006346 DNA methylation-dependent heterochromatin assembly 2/719 20/18722 0.178036444028403 0.596540002999995 HELLS/DNMT1 2 GO:0006448 regulation of translational elongation 2/719 20/18722 0.178036444028403 0.596540002999995 SRP9/EIF5A 2 GO:0010801 negative regulation of peptidyl-threonine phosphorylation 2/719 20/18722 0.178036444028403 0.596540002999995 CALM2/CALM1 2 GO:0030150 protein import into mitochondrial matrix 2/719 20/18722 0.178036444028403 0.596540002999995 ROMO1/TOMM40 2 GO:0032930 positive regulation of superoxide anion generation 2/719 20/18722 0.178036444028403 0.596540002999995 GSTP1/SOD1 2 GO:0043555 regulation of translation in response to stress 2/719 20/18722 0.178036444028403 0.596540002999995 NPM1/PPP1CA 2 GO:0046931 pore complex assembly 2/719 20/18722 0.178036444028403 0.596540002999995 CCT8/CCT3 2 GO:1901679 nucleotide transmembrane transport 2/719 20/18722 0.178036444028403 0.596540002999995 SLC25A5/SLC25A6 2 GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 2/719 20/18722 0.178036444028403 0.596540002999995 PPIA/PARK7 2 GO:1903206 negative regulation of hydrogen peroxide-induced cell death 2/719 20/18722 0.178036444028403 0.596540002999995 TXN/PARK7 2 GO:1903817 negative regulation of voltage-gated potassium channel activity 2/719 20/18722 0.178036444028403 0.596540002999995 CAV1/SUMO1 2 GO:0009309 amine biosynthetic process 3/719 38/18722 0.178187273623375 0.596540002999995 PARK7/SMS/SRM 3 GO:0072524 pyridine-containing compound metabolic process 3/719 38/18722 0.178187273623375 0.596540002999995 IDH2/PNP/QPRT 3 GO:1901031 regulation of response to reactive oxygen species 3/719 38/18722 0.178187273623375 0.596540002999995 TXN/DHFR/PARK7 3 GO:0006304 DNA modification 7/719 120/18722 0.178821161617083 0.597622805751535 HELLS/UNG/EZH2/APEX1/MIS18A/PARP1/DNMT1 7 GO:0051897 positive regulation of protein kinase B signaling 7/719 120/18722 0.178821161617083 0.597622805751535 TXN/PARK7/HSP90AB1/C1QBP/HSP90AA1/PHB/ITGB1BP1 7 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 5/719 78/18722 0.180261703875971 0.601200286528603 HSPE1/ANP32B/HSPD1/CYCS/BAX 5 GO:0070373 negative regulation of ERK1 and ERK2 cascade 5/719 78/18722 0.180261703875971 0.601200286528603 GSTP1/DUSP9/PHB/PIN1/ITGB1BP1 5 GO:0050792 regulation of viral process 9/719 164/18722 0.180360085958581 0.601200286528603 PPIA/TOP2A/LY6E/KPNA2/DYNLT1/BANF1/SNX3/PPIH/RAD23A 9 GO:1902905 positive regulation of supramolecular fiber organization 11/719 209/18722 0.181711119086289 0.605179765123022 S100A10/RPS3/PFN1/DSTN/ARL2/ARPC1A/ARPC5/RHOC/ARPC5L/ID1/ITGB1BP1 11 GO:0043666 regulation of phosphoprotein phosphatase activity 4/719 58/18722 0.182753571591432 0.608125540732079 CALM2/CALM1/HSP90AB1/CSNK2B 4 GO:0046661 male sex differentiation 9/719 165/18722 0.18477192153482 0.614310792667579 HMGB2/NASP/RRM1/EIF2S2/UBB/NUDT1/MEA1/CCND1/BAX 9 GO:0031023 microtubule organizing center organization 8/719 143/18722 0.185082714249092 0.614813157773085 CDK1/RANBP1/NPM1/AURKA/HAUS1/ARL2/UXT/NSFL1C 8 GO:0007623 circadian rhythm 11/719 210/18722 0.18561046155024 0.616034721524503 TYMS/CDK1/TOP2A/HNRNPD/PPP1CA/IMPDH2/EZH2/CDK4/HNRNPR/ID1/ID3 11 GO:0044728 DNA methylation or demethylation 6/719 100/18722 0.186519594612659 0.617823825167784 HELLS/EZH2/APEX1/MIS18A/PARP1/DNMT1 6 GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 5/719 79/18722 0.186836139821592 0.617823825167784 GAPDH/HMGN2/RPS19/RPL30/ROMO1 5 GO:0002347 response to tumor cell 3/719 39/18722 0.1879147270835 0.617823825167784 HMGB1/PRDX2/HSPD1 3 GO:0016233 telomere capping 3/719 39/18722 0.1879147270835 0.617823825167784 AURKB/HNRNPD/PKIB 3 GO:0031507 heterochromatin assembly 3/719 39/18722 0.1879147270835 0.617823825167784 HELLS/DNMT1/POLE3 3 GO:0032728 positive regulation of interferon-beta production 3/719 39/18722 0.1879147270835 0.617823825167784 HMGB2/HMGB1/HSP90AA1 3 GO:0034314 Arp2/3 complex-mediated actin nucleation 3/719 39/18722 0.1879147270835 0.617823825167784 ARPC1A/ARPC5/ARPC5L 3 GO:0036297 interstrand cross-link repair 3/719 39/18722 0.1879147270835 0.617823825167784 RAD51/RAD51AP1/NUCKS1 3 GO:0042417 dopamine metabolic process 3/719 39/18722 0.1879147270835 0.617823825167784 PARK7/COMT/PNKD 3 GO:0051084 'de novo' posttranslational protein folding 3/719 39/18722 0.1879147270835 0.617823825167784 HSPE1/PTGES3/CCT2 3 GO:1901021 positive regulation of calcium ion transmembrane transporter activity 3/719 39/18722 0.1879147270835 0.617823825167784 CALM2/GSTO1/CALM1 3 GO:1902904 negative regulation of supramolecular fiber organization 9/719 166/18722 0.189231163784231 0.621621143830453 STMN1/PFN1/TPX2/CKAP2/PFDN2/MKKS/PFDN4/VBP1/PFDN1 9 GO:0042180 cellular ketone metabolic process 11/719 211/18722 0.189548182374008 0.62213171537931 TPI1/PARK7/COMT/AKR7A2/CAV1/AKR1B1/EIF6/PNKD/GLO1/VKORC1/HSD17B10 11 GO:0001890 placenta development 8/719 144/18722 0.189898131981287 0.622409080044204 RPS6/KRT19/SOD1/KRT8/HSP90AB1/PHLDA2/PRDX3/MDFI 8 GO:0032768 regulation of monooxygenase activity 4/719 59/18722 0.190546189324619 0.622409080044204 CALM1/DHFR/PARK7/CAV1 4 GO:0090303 positive regulation of wound healing 4/719 59/18722 0.190546189324619 0.622409080044204 HMGB1/PRDX2/ACTG1/HRAS 4 GO:0002689 negative regulation of leukocyte chemotaxis 2/719 21/18722 0.192057658985069 0.622409080044204 MIF/DDT 2 GO:0006450 regulation of translational fidelity 2/719 21/18722 0.192057658985069 0.622409080044204 RPS5/RPS9 2 GO:0006925 inflammatory cell apoptotic process 2/719 21/18722 0.192057658985069 0.622409080044204 CDKN2A/TCP1 2 GO:0007063 regulation of sister chromatid cohesion 2/719 21/18722 0.192057658985069 0.622409080044204 FEN1/NAA10 2 GO:0030449 regulation of complement activation 2/719 21/18722 0.192057658985069 0.622409080044204 C1QBP/PHB 2 GO:0033762 response to glucagon 2/719 21/18722 0.192057658985069 0.622409080044204 CCNA2/CYC1 2 GO:0033962 P-body assembly 2/719 21/18722 0.192057658985069 0.622409080044204 LSM3/LSM4 2 GO:0046597 negative regulation of viral entry into host cell 2/719 21/18722 0.192057658985069 0.622409080044204 LY6E/SNX3 2 GO:0071605 monocyte chemotactic protein-1 production 2/719 21/18722 0.192057658985069 0.622409080044204 HMGB1/GSTP1 2 GO:0071637 regulation of monocyte chemotactic protein-1 production 2/719 21/18722 0.192057658985069 0.622409080044204 HMGB1/GSTP1 2 GO:0090141 positive regulation of mitochondrial fission 2/719 21/18722 0.192057658985069 0.622409080044204 AURKA/BNIP3 2 GO:1902644 tertiary alcohol metabolic process 2/719 21/18722 0.192057658985069 0.622409080044204 AKR7A2/AKR1B1 2 GO:0021766 hippocampus development 5/719 80/18722 0.193495992065297 0.626016444917138 UQCRQ/NME1/ANXA3/EZH2/MKKS 5 GO:0051303 establishment of chromosome localization 5/719 80/18722 0.193495992065297 0.626016444917138 AURKB/CDT1/NUF2/CCNB1/NUDC 5 GO:0043524 negative regulation of neuron apoptotic process 8/719 145/18722 0.194765885411268 0.629595851245494 SOD1/PARK7/HSP90AB1/HSPD1/SET/PIN1/HRAS/BAX 8 GO:0051051 negative regulation of transport 22/719 470/18722 0.197636082656522 0.636118571698339 HMGB1/CALM2/GSTO1/TXN/CALM1/PARK7/VDAC1/COMT/IDH2/YWHAE/ENY2/CAV1/VAMP8/YWHAQ/HADH/PNKD/SNX3/C4orf3/PPIF/SUMO1/ISCU/ITGB1BP1 22 GO:0010863 positive regulation of phospholipase C activity 3/719 40/18722 0.19777504683712 0.636118571698339 PHB/PHB2/HRAS 3 GO:0031111 negative regulation of microtubule polymerization or depolymerization 3/719 40/18722 0.19777504683712 0.636118571698339 STMN1/TPX2/CKAP2 3 GO:0071276 cellular response to cadmium ion 3/719 40/18722 0.19777504683712 0.636118571698339 MT2A/SOD1/SUMO1 3 GO:1901661 quinone metabolic process 3/719 40/18722 0.19777504683712 0.636118571698339 AKR7A2/AKR1B1/VKORC1 3 GO:2000142 regulation of DNA-templated transcription, initiation 3/719 40/18722 0.19777504683712 0.636118571698339 HMGB1/SUB1/CDK4 3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 4/719 60/18722 0.198441731575367 0.637198220654847 HNRNPA1/SAP18/MAGOH/RBM8A 4 GO:0051851 modulation by host of symbiont process 4/719 60/18722 0.198441731575367 0.637198220654847 NUCKS1/CFL1/PSMC3/PHB 4 GO:0000422 autophagy of mitochondrion 5/719 81/18722 0.200237861360163 0.639764121358198 SLC25A5/PARK7/VDAC1/PHB2/BNIP3 5 GO:0021954 central nervous system neuron development 5/719 81/18722 0.200237861360163 0.639764121358198 UQCRQ/UBB/HSP90AB1/HSP90AA1/C12orf57 5 GO:0046209 nitric oxide metabolic process 5/719 81/18722 0.200237861360163 0.639764121358198 DYNLL1/HSP90AB1/HSP90AA1/CAV1/CYB5B 5 GO:0051817 modulation of process of other organism involved in symbiotic interaction 5/719 81/18722 0.200237861360163 0.639764121358198 NUCKS1/CFL1/PSMC3/PHB/PHB2 5 GO:0061726 mitochondrion disassembly 5/719 81/18722 0.200237861360163 0.639764121358198 SLC25A5/PARK7/VDAC1/PHB2/BNIP3 5 GO:2000106 regulation of leukocyte apoptotic process 5/719 81/18722 0.200237861360163 0.639764121358198 AURKB/PRELID1/CDKN2A/TCP1/BAX 5 GO:0019318 hexose metabolic process 12/719 237/18722 0.202011675325939 0.644362013260039 HMGB1/GAPDH/ENO1/TPI1/ALDOA/PPP1CA/PGP/PHLDA2/DCXR/AKR1B1/LCMT1/SLC25A1 12 GO:1901617 organic hydroxy compound biosynthetic process 12/719 237/18722 0.202011675325939 0.644362013260039 SOD1/DHFR/PARK7/FDPS/PGP/IMPA2/AKR1B1/ISYNA1/DDT/PCBD1/HSD17B10/PTS 12 GO:0006662 glycerol ether metabolic process 2/719 22/18722 0.20621547975774 0.652366143851518 TXN/TXN2 2 GO:0016137 glycoside metabolic process 2/719 22/18722 0.20621547975774 0.652366143851518 AKR7A2/AKR1B1 2 GO:0031061 negative regulation of histone methylation 2/719 22/18722 0.20621547975774 0.652366143851518 PIH1D1/DNMT1 2 GO:0032098 regulation of appetite 2/719 22/18722 0.20621547975774 0.652366143851518 NENF/MKKS 2 GO:0032727 positive regulation of interferon-alpha production 2/719 22/18722 0.20621547975774 0.652366143851518 HMGB1/HSPD1 2 GO:0035561 regulation of chromatin binding 2/719 22/18722 0.20621547975774 0.652366143851518 GMNN/CDT1 2 GO:0051412 response to corticosterone 2/719 22/18722 0.20621547975774 0.652366143851518 CALM1/CCND1 2 GO:0071359 cellular response to dsRNA 2/719 22/18722 0.20621547975774 0.652366143851518 NPM1/CAV1 2 GO:1900120 regulation of receptor binding 2/719 22/18722 0.20621547975774 0.652366143851518 ANXA2/PHLDA2 2 GO:1901032 negative regulation of response to reactive oxygen species 2/719 22/18722 0.20621547975774 0.652366143851518 TXN/PARK7 2 GO:0050000 chromosome localization 5/719 82/18722 0.207058311435492 0.653957751457461 AURKB/CDT1/NUF2/CCNB1/NUDC 5 GO:2001057 reactive nitrogen species metabolic process 5/719 82/18722 0.207058311435492 0.653957751457461 DYNLL1/HSP90AB1/HSP90AA1/CAV1/CYB5B 5 GO:0055023 positive regulation of cardiac muscle tissue growth 3/719 41/18722 0.207756537869497 0.655088182471388 CDK1/CCNB1/PIN1 3 GO:0070296 sarcoplasmic reticulum calcium ion transport 3/719 41/18722 0.207756537869497 0.655088182471388 CALM2/GSTO1/CALM1 3 GO:0031330 negative regulation of cellular catabolic process 13/719 262/18722 0.209309750726591 0.659445613991307 PBK/RPL11/RPS7/RPL5/YBX1/PARK7/ANXA2/RPL23/SLIRP/HSP90AB1/HNRNPD/EIF3H/TAF9 13 GO:1903900 regulation of viral life cycle 8/719 148/18722 0.209671289469138 0.660044533488293 PPIA/TOP2A/LY6E/KPNA2/BANF1/SNX3/PPIH/RAD23A 8 GO:0043254 regulation of protein-containing complex assembly 20/719 427/18722 0.210457255632619 0.66197747890979 STMN1/HMGB1/RPS3/PFN1/RPL13A/CDT1/PARK7/ARL2/HSP90AA1/ARPC1A/VDAC2/ARPC5/PIH1D1/LCMT1/RHOC/ARPC5L/PARP1/MKKS/SUMO1/BAX 20 GO:0045428 regulation of nitric oxide biosynthetic process 4/719 62/18722 0.214518410357364 0.673101776589936 DYNLL1/HSP90AB1/HSP90AA1/CAV1 4 GO:0046148 pigment biosynthetic process 4/719 62/18722 0.214518410357364 0.673101776589936 PAICS/GMPS/DDT/APRT 4 GO:0070265 necrotic cell death 4/719 62/18722 0.214518410357364 0.673101776589936 CAV1/PPIF/BNIP3/BAX 4 GO:0051592 response to calcium ion 8/719 149/18722 0.214736399172047 0.673237082094774 CALM2/CALM1/CACYBP/HNRNPD/CAV1/ECT2/CCND1/PPIF 8 GO:1901136 carbohydrate derivative catabolic process 9/719 172/18722 0.216931268063435 0.679564997594975 DUT/HINT1/DCTPP1/UNG/DNPH1/NUDT1/NUDT8/NUDT15/PNP 9 GO:0009154 purine ribonucleotide catabolic process 3/719 42/18722 0.217847713659328 0.679992124485605 HINT1/NUDT8/PNP 3 GO:0010939 regulation of necrotic cell death 3/719 42/18722 0.217847713659328 0.679992124485605 CAV1/PPIF/BNIP3 3 GO:0032467 positive regulation of cytokinesis 3/719 42/18722 0.217847713659328 0.679992124485605 AURKB/CDC6/ECT2 3 GO:1900274 regulation of phospholipase C activity 3/719 42/18722 0.217847713659328 0.679992124485605 PHB/PHB2/HRAS 3 GO:1901605 alpha-amino acid metabolic process 10/719 195/18722 0.217950722497464 0.679992124485605 GCSH/DHFR/PARK7/COMT/GMPS/ADI1/SMS/PCBD1/NIT2/HSD17B10 10 GO:0001919 regulation of receptor recycling 2/719 23/18722 0.220478790175383 0.683169542200244 ANXA2/NSG1 2 GO:0006541 glutamine metabolic process 2/719 23/18722 0.220478790175383 0.683169542200244 GMPS/NIT2 2 GO:0021884 forebrain neuron development 2/719 23/18722 0.220478790175383 0.683169542200244 UQCRQ/UBB 2 GO:0042026 protein refolding 2/719 23/18722 0.220478790175383 0.683169542200244 HSPD1/HSP90AA1 2 GO:0045943 positive regulation of transcription by RNA polymerase I 2/719 23/18722 0.220478790175383 0.683169542200244 NCL/PIH1D1 2 GO:0050765 negative regulation of phagocytosis 2/719 23/18722 0.220478790175383 0.683169542200244 HMGB1/SNX3 2 GO:0051349 positive regulation of lyase activity 2/719 23/18722 0.220478790175383 0.683169542200244 PARK7/ISCU 2 GO:2001169 regulation of ATP biosynthetic process 2/719 23/18722 0.220478790175383 0.683169542200244 ENO1/PARP1 2 GO:0006112 energy reserve metabolic process 5/719 84/18722 0.220921059750468 0.683169542200244 HMGB1/PTGES3/PPP1CA/PHLDA2/UGP2 5 GO:0032370 positive regulation of lipid transport 5/719 84/18722 0.220921059750468 0.683169542200244 DBI/ANXA2/PRELID1/TRIAP1/CAV1 5 GO:1900542 regulation of purine nucleotide metabolic process 5/719 84/18722 0.220921059750468 0.683169542200244 ENO1/PGAM1/ARL2/EIF6/PARP1 5 GO:0009746 response to hexose 11/719 219/18722 0.222359889125206 0.68587891745412 LDHA/PHPT1/DYNLL1/NME1/KRT18/MPC2/ENY2/PIH1D1/TXN2/SLC29A1/ENSA 11 GO:0006006 glucose metabolic process 10/719 196/18722 0.222424199499609 0.68587891745412 HMGB1/GAPDH/ENO1/TPI1/PPP1CA/PGP/PHLDA2/DCXR/LCMT1/SLC25A1 10 GO:0071887 leukocyte apoptotic process 6/719 106/18722 0.222650893383515 0.68587891745412 RPS6/AURKB/PRELID1/CDKN2A/TCP1/BAX 6 GO:0030239 myofibril assembly 4/719 63/18722 0.222687960212377 0.68587891745412 CSRP2/ACTG1/KRT19/KRT8 4 GO:2000756 regulation of peptidyl-lysine acetylation 4/719 63/18722 0.222687960212377 0.68587891745412 PARK7/SET/HINT2/PIH1D1 4 GO:2001236 regulation of extrinsic apoptotic signaling pathway 8/719 151/18722 0.225004027079846 0.692458436656599 HMGB2/PRDX2/GSTP1/PARK7/BCL2L12/PPP1CA/CAV1/FAIM 8 GO:0045069 regulation of viral genome replication 5/719 85/18722 0.227956353767619 0.700114567366692 PPIA/TOP2A/BANF1/PPIH/RAD23A 5 GO:0031952 regulation of protein autophosphorylation 3/719 43/18722 0.228037316228008 0.700114567366692 CALM2/CALM1/CAV1 3 GO:0060443 mammary gland morphogenesis 3/719 43/18722 0.228037316228008 0.700114567366692 CAV1/PHB2/BAX 3 GO:0018209 peptidyl-serine modification 16/719 338/18722 0.229470930068947 0.703954646028245 CDK1/AURKB/TXN/MIF/CLSPN/CCNB1/PARK7/AURKA/VRK1/HSP90AB1/HSP90AA1/CAV1/PARP1/NTMT1/NAA10/BAX 16 GO:0008406 gonad development 11/719 221/18722 0.230903331362005 0.705082110525583 HMGB2/NASP/RRM1/SOD1/EIF2S2/UBB/NUDT1/MEA1/CCND1/MKKS/BAX 11 GO:0055002 striated muscle cell development 4/719 64/18722 0.230937283473444 0.705082110525583 CSRP2/ACTG1/KRT19/KRT8 4 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 4/719 64/18722 0.230937283473444 0.705082110525583 PHPT1/DYNLL1/MPC2/ENY2 4 GO:0070542 response to fatty acid 4/719 64/18722 0.230937283473444 0.705082110525583 CCNB1/NME1/CDK4/ID3 4 GO:0080164 regulation of nitric oxide metabolic process 4/719 64/18722 0.230937283473444 0.705082110525583 DYNLL1/HSP90AB1/HSP90AA1/CAV1 4 GO:1903409 reactive oxygen species biosynthetic process 4/719 64/18722 0.230937283473444 0.705082110525583 PAGE4/SOD1/PARK7/HSPD1 4 GO:0007568 aging 16/719 339/18722 0.23293046089775 0.710604020963817 TYMS/CDK1/NPM1/AURKB/HMGA1/MIF/YBX1/SOD1/CACYBP/GPX4/ROMO1/NUDT1/CDKN2A/EEF1E1/APEX1/HRAS 16 GO:0000395 mRNA 5'-splice site recognition 2/719 24/18722 0.234818656435591 0.710708136742111 SNRPC/PSIP1 2 GO:0001783 B cell apoptotic process 2/719 24/18722 0.234818656435591 0.710708136742111 AURKB/BAX 2 GO:0010288 response to lead ion 2/719 24/18722 0.234818656435591 0.710708136742111 PPP1CA/CDK4 2 GO:0032928 regulation of superoxide anion generation 2/719 24/18722 0.234818656435591 0.710708136742111 GSTP1/SOD1 2 GO:0033032 regulation of myeloid cell apoptotic process 2/719 24/18722 0.234818656435591 0.710708136742111 CDKN2A/TCP1 2 GO:0051000 positive regulation of nitric-oxide synthase activity 2/719 24/18722 0.234818656435591 0.710708136742111 CALM1/DHFR 2 GO:0051156 glucose 6-phosphate metabolic process 2/719 24/18722 0.234818656435591 0.710708136742111 PGAM1/TALDO1 2 GO:0051570 regulation of histone H3-K9 methylation 2/719 24/18722 0.234818656435591 0.710708136742111 PIH1D1/DNMT1 2 GO:0071294 cellular response to zinc ion 2/719 24/18722 0.234818656435591 0.710708136742111 MT2A/PARP1 2 GO:2000679 positive regulation of transcription regulatory region DNA binding 2/719 24/18722 0.234818656435591 0.710708136742111 PARK7/PARP1 2 GO:0006140 regulation of nucleotide metabolic process 5/719 86/18722 0.235056231315666 0.710708136742111 ENO1/PGAM1/ARL2/EIF6/PARP1 5 GO:0033138 positive regulation of peptidyl-serine phosphorylation 6/719 108/18722 0.235179783431026 0.710708136742111 TXN/MIF/PARK7/HSP90AB1/HSP90AA1/CAV1 6 GO:0051402 neuron apoptotic process 12/719 246/18722 0.238036297070804 0.716245265009559 GAPDH/SOD1/PARK7/HSP90AB1/HSPD1/SET/PARP1/PIN1/NAE1/HRAS/BNIP3/BAX 12 GO:0005978 glycogen biosynthetic process 3/719 44/18722 0.238314333630453 0.716245265009559 PTGES3/PPP1CA/UGP2 3 GO:0009250 glucan biosynthetic process 3/719 44/18722 0.238314333630453 0.716245265009559 PTGES3/PPP1CA/UGP2 3 GO:0032881 regulation of polysaccharide metabolic process 3/719 44/18722 0.238314333630453 0.716245265009559 HMGB1/PPP1CA/PHLDA2 3 GO:0046006 regulation of activated T cell proliferation 3/719 44/18722 0.238314333630453 0.716245265009559 HMGB1/RPS3/CD24 3 GO:0050999 regulation of nitric-oxide synthase activity 3/719 44/18722 0.238314333630453 0.716245265009559 CALM1/DHFR/CAV1 3 GO:0097178 ruffle assembly 3/719 44/18722 0.238314333630453 0.716245265009559 PFN1/CAV1/HRAS 3 GO:0046683 response to organophosphorus 7/719 131/18722 0.238986447313167 0.717705009481821 TYMS/LDHA/SOD1/NME1/RFC3/HSPD1/APEX1 7 GO:0071466 cellular response to xenobiotic stimulus 9/719 177/18722 0.241145107208066 0.723623275721788 PCNA/GSTO1/GSTP1/MCM7/NME1/NUDT15/VKORC1/UMPS/CYB5B 9 GO:0006631 fatty acid metabolic process 18/719 390/18722 0.243996082011361 0.731608189831573 GSTP1/MIF/PTGES3/ACAT2/ECHS1/ETFB/GPX4/ECH1/ECI1/NDUFAB1/CAV1/NUDT8/AKR1B1/ADH5/EIF6/HADH/ETFA/HSD17B10 18 GO:0009266 response to temperature stimulus 9/719 178/18722 0.246098927115484 0.737339197972463 SOD1/HSP90AB1/YWHAE/PSIP1/HSBP1/HSPD1/HSP90AA1/RBBP7/SUMO1 9 GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 4/719 66/18722 0.247652323006807 0.740317586557182 HMGB2/HMGB1/UNG/HSPD1 4 GO:0016444 somatic cell DNA recombination 4/719 66/18722 0.247652323006807 0.740317586557182 HMGB2/HMGB1/UNG/HSPD1 4 GO:0018958 phenol-containing compound metabolic process 6/719 110/18722 0.247919561369421 0.740317586557182 LY6E/PARK7/COMT/AKR1B1/PNKD/DDT 6 GO:0006110 regulation of glycolytic process 3/719 45/18722 0.248668015081053 0.740317586557182 PGAM1/ARL2/EIF6 3 GO:0048538 thymus development 3/719 45/18722 0.248668015081053 0.740317586557182 PRDX2/CCNB2/SOD1 3 GO:0060421 positive regulation of heart growth 3/719 45/18722 0.248668015081053 0.740317586557182 CDK1/CCNB1/PIN1 3 GO:0010954 positive regulation of protein processing 2/719 25/18722 0.249208205760547 0.740317586557182 ENO1/BAG2 2 GO:0032104 regulation of response to extracellular stimulus 2/719 25/18722 0.249208205760547 0.740317586557182 NENF/MKKS 2 GO:0032107 regulation of response to nutrient levels 2/719 25/18722 0.249208205760547 0.740317586557182 NENF/MKKS 2 GO:0060074 synapse maturation 2/719 25/18722 0.249208205760547 0.740317586557182 PFN1/CDC20 2 GO:1904385 cellular response to angiotensin 2/719 25/18722 0.249208205760547 0.740317586557182 CDC6/CAV1 2 GO:0016042 lipid catabolic process 15/719 320/18722 0.250100019110976 0.742394042850622 YWHAH/ACAT2/PRDX6/ECHS1/ETFB/ECH1/ECI1/PAFAH1B3/HINT2/NUDT8/HADH/ETFA/CDK4/IAH1/HSD17B10 15 GO:0006997 nucleus organization 7/719 133/18722 0.25057816144617 0.743240309374234 HMGB2/CDK1/RPS19/VRK1/SERBP1/UBE2I/NSFL1C 7 GO:0006513 protein monoubiquitination 4/719 67/18722 0.256106681061206 0.757311728401618 UBE2T/UBB/RBX1/SKP1 4 GO:0061077 chaperone-mediated protein folding 4/719 67/18722 0.256106681061206 0.757311728401618 HSPE1/PTGES3/PDCD5/CCT2 4 GO:0070527 platelet aggregation 4/719 67/18722 0.256106681061206 0.757311728401618 PPIA/ACTG1/GNAS/FIBP 4 GO:0043409 negative regulation of MAPK cascade 9/719 180/18722 0.256109057241275 0.757311728401618 PPIA/GSTP1/PBK/PEBP1/DUSP9/CAV1/PHB/PIN1/ITGB1BP1 9 GO:0051781 positive regulation of cell division 5/719 89/18722 0.256708008990976 0.758224577663279 AURKB/CDC6/YBX1/ECT2/ITGB1BP1 5 GO:0070646 protein modification by small protein removal 8/719 157/18722 0.256811649161796 0.758224577663279 CDK1/HINT1/PARK7/EIF3F/ENY2/PSMD14/COPS3/USP1 8 GO:0045137 development of primary sexual characteristics 11/719 227/18722 0.25726301458603 0.758975177131199 HMGB2/NASP/RRM1/SOD1/EIF2S2/UBB/NUDT1/MEA1/CCND1/MKKS/BAX 11 GO:0007019 microtubule depolymerization 3/719 46/18722 0.259087883896247 0.762605774465252 STMN1/TPX2/CKAP2 3 GO:0031057 negative regulation of histone modification 3/719 46/18722 0.259087883896247 0.762605774465252 SET/PIH1D1/DNMT1 3 GO:0070828 heterochromatin organization 3/719 46/18722 0.259087883896247 0.762605774465252 HELLS/DNMT1/POLE3 3 GO:0001556 oocyte maturation 2/719 26/18722 0.263622511133888 0.768898990807172 CCNB1/AURKA 2 GO:0001963 synaptic transmission, dopaminergic 2/719 26/18722 0.263622511133888 0.768898990807172 PARK7/PNKD 2 GO:0002026 regulation of the force of heart contraction 2/719 26/18722 0.263622511133888 0.768898990807172 CAV1/GLRX3 2 GO:0002407 dendritic cell chemotaxis 2/719 26/18722 0.263622511133888 0.768898990807172 HMGB1/C1QBP 2 GO:0002418 immune response to tumor cell 2/719 26/18722 0.263622511133888 0.768898990807172 HMGB1/HSPD1 2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane 2/719 26/18722 0.263622511133888 0.768898990807172 SRP14/SRP9 2 GO:0009164 nucleoside catabolic process 2/719 26/18722 0.263622511133888 0.768898990807172 NUDT1/PNP 2 GO:0051560 mitochondrial calcium ion homeostasis 2/719 26/18722 0.263622511133888 0.768898990807172 BNIP3/MCUR1 2 GO:0060295 regulation of cilium movement involved in cell motility 2/719 26/18722 0.263622511133888 0.768898990807172 CFAP20/MKKS 2 GO:0060352 cell adhesion molecule production 2/719 26/18722 0.263622511133888 0.768898990807172 PPIA/CAV1 2 GO:0097066 response to thyroid hormone 2/719 26/18722 0.263622511133888 0.768898990807172 ANXA2/AKR1B1 2 GO:1902019 regulation of cilium-dependent cell motility 2/719 26/18722 0.263622511133888 0.768898990807172 CFAP20/MKKS 2 GO:0061912 selective autophagy 4/719 68/18722 0.264618113396896 0.770635201647542 SLC25A5/VDAC1/PHB2/UFC1 4 GO:1901607 alpha-amino acid biosynthetic process 4/719 68/18722 0.264618113396896 0.770635201647542 DHFR/PARK7/ADI1/PCBD1 4 GO:0006998 nuclear envelope organization 3/719 47/18722 0.269563748423838 0.780903259166121 VRK1/UBE2I/NSFL1C 3 GO:0009261 ribonucleotide catabolic process 3/719 47/18722 0.269563748423838 0.780903259166121 HINT1/NUDT8/PNP 3 GO:0016073 snRNA metabolic process 3/719 47/18722 0.269563748423838 0.780903259166121 NHP2/EXOSC8/NOP10 3 GO:0016574 histone ubiquitination 3/719 47/18722 0.269563748423838 0.780903259166121 PARK7/UBE2N/SKP1 3 GO:0050798 activated T cell proliferation 3/719 47/18722 0.269563748423838 0.780903259166121 HMGB1/RPS3/CD24 3 GO:0072583 clathrin-dependent endocytosis 3/719 47/18722 0.269563748423838 0.780903259166121 AP2S1/CLTA/CLTB 3 GO:0097300 programmed necrotic cell death 3/719 47/18722 0.269563748423838 0.780903259166121 CAV1/PPIF/BAX 3 GO:0022898 regulation of transmembrane transporter activity 13/719 278/18722 0.272583929512134 0.789058743324599 CALM2/GSTO1/CALM1/YWHAH/PARK7/NDUFA4/YWHAE/COX17/CAV1/C4orf3/PPIF/PHB2/SUMO1 13 GO:0060193 positive regulation of lipase activity 4/719 69/18722 0.273181084223987 0.78959998067744 RHOC/PHB/PHB2/HRAS 4 GO:1901224 positive regulation of NIK/NF-kappaB signaling 4/719 69/18722 0.273181084223987 0.78959998067744 HMGB1/RPS3/PHB/PHB2 4 GO:0000469 cleavage involved in rRNA processing 2/719 27/18722 0.27803848183134 0.792337642524545 NHP2/EXOSC8 2 GO:0000737 DNA catabolic process, endonucleolytic 2/719 27/18722 0.27803848183134 0.792337642524545 APEX1/BAX 2 GO:0001835 blastocyst hatching 2/719 27/18722 0.27803848183134 0.792337642524545 ASF1B/NDUFA2 2 GO:0007026 negative regulation of microtubule depolymerization 2/719 27/18722 0.27803848183134 0.792337642524545 TPX2/CKAP2 2 GO:0010758 regulation of macrophage chemotaxis 2/719 27/18722 0.27803848183134 0.792337642524545 MIF/DDT 2 GO:0018195 peptidyl-arginine modification 2/719 27/18722 0.27803848183134 0.792337642524545 PARK7/PRMT1 2 GO:0018904 ether metabolic process 2/719 27/18722 0.27803848183134 0.792337642524545 TXN/TXN2 2 GO:0031954 positive regulation of protein autophosphorylation 2/719 27/18722 0.27803848183134 0.792337642524545 CALM2/CALM1 2 GO:0035188 hatching 2/719 27/18722 0.27803848183134 0.792337642524545 ASF1B/NDUFA2 2 GO:0042402 cellular biogenic amine catabolic process 2/719 27/18722 0.27803848183134 0.792337642524545 COMT/ALDH7A1 2 GO:0046174 polyol catabolic process 2/719 27/18722 0.27803848183134 0.792337642524545 TPI1/IMPA2 2 GO:0048873 homeostasis of number of cells within a tissue 2/719 27/18722 0.27803848183134 0.792337642524545 FH/BAX 2 GO:0071684 organism emergence from protective structure 2/719 27/18722 0.27803848183134 0.792337642524545 ASF1B/NDUFA2 2 GO:0098901 regulation of cardiac muscle cell action potential 2/719 27/18722 0.27803848183134 0.792337642524545 CALM1/CAV1 2 GO:1902883 negative regulation of response to oxidative stress 2/719 27/18722 0.27803848183134 0.792337642524545 TXN/PARK7 2 GO:1903203 regulation of oxidative stress-induced neuron death 2/719 27/18722 0.27803848183134 0.792337642524545 PARK7/PARP1 2 GO:1903205 regulation of hydrogen peroxide-induced cell death 2/719 27/18722 0.27803848183134 0.792337642524545 TXN/PARK7 2 GO:1903319 positive regulation of protein maturation 2/719 27/18722 0.27803848183134 0.792337642524545 ENO1/BAG2 2 GO:1904357 negative regulation of telomere maintenance via telomere lengthening 2/719 27/18722 0.27803848183134 0.792337642524545 HNRNPA1/PARP1 2 GO:1901215 negative regulation of neuron death 10/719 208/18722 0.278656860308103 0.793512509013458 SOD1/PARK7/HSP90AB1/HSPD1/SET/PSMC1/NENF/PIN1/HRAS/BAX 10 GO:0032273 positive regulation of protein polymerization 7/719 138/18722 0.280251977876074 0.797464977696145 RPS3/PFN1/ARL2/HSP90AA1/ARPC1A/ARPC5/ARPC5L 7 GO:0090398 cellular senescence 5/719 93/18722 0.286266995419342 0.813378547870454 HMGA1/YBX1/CDKN2A/EEF1E1/HRAS 5 GO:1901019 regulation of calcium ion transmembrane transporter activity 5/719 93/18722 0.286266995419342 0.813378547870454 CALM2/GSTO1/CALM1/YWHAE/C4orf3 5 GO:0030518 intracellular steroid hormone receptor signaling pathway 6/719 116/18722 0.287209684641853 0.815455225568684 YWHAH/PTGES3/PARK7/PHB/PARP1/PHB2 6 GO:0050878 regulation of body fluid levels 17/719 379/18722 0.289791231754987 0.819413263437997 STMN1/PPIA/PRDX2/ANXA5/ACTG1/NME1/ANXA2/GNAS/CAV1/VAMP8/AKR1B1/CCND1/APRT/SLC29A1/VKORC1/FIBP/UMPS 17 GO:0050818 regulation of coagulation 4/719 71/18722 0.290439859379942 0.819413263437997 PRDX2/ANXA5/ANXA2/CAV1 4 GO:0009066 aspartate family amino acid metabolic process 3/719 49/18722 0.290644175911598 0.819413263437997 ADI1/SMS/NIT2 3 GO:0052372 modulation by symbiont of entry into host 3/719 49/18722 0.290644175911598 0.819413263437997 LY6E/CAV1/SNX3 3 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 3/719 49/18722 0.290644175911598 0.819413263437997 HMGB2/PARK7/FAIM 3 GO:0007292 female gamete generation 7/719 140/18722 0.292361307125417 0.819413263437997 TOP2A/RPS6/CCNB2/CCNB1/AURKA/UBB/RAD51C 7 GO:0006972 hyperosmotic response 2/719 28/18722 0.292434759471119 0.819413263437997 XRCC6/AKR1B1 2 GO:0007141 male meiosis I 2/719 28/18722 0.292434759471119 0.819413263437997 UBB/RAD51C 2 GO:0030262 apoptotic nuclear changes 2/719 28/18722 0.292434759471119 0.819413263437997 TOP2A/BAX 2 GO:0032607 interferon-alpha production 2/719 28/18722 0.292434759471119 0.819413263437997 HMGB1/HSPD1 2 GO:0032647 regulation of interferon-alpha production 2/719 28/18722 0.292434759471119 0.819413263437997 HMGB1/HSPD1 2 GO:0034123 positive regulation of toll-like receptor signaling pathway 2/719 28/18722 0.292434759471119 0.819413263437997 HMGB1/CAV1 2 GO:0051894 positive regulation of focal adhesion assembly 2/719 28/18722 0.292434759471119 0.819413263437997 S100A10/ITGB1BP1 2 GO:0060765 regulation of androgen receptor signaling pathway 2/719 28/18722 0.292434759471119 0.819413263437997 PARK7/PHB 2 GO:0086011 membrane repolarization during action potential 2/719 28/18722 0.292434759471119 0.819413263437997 YWHAE/CAV1 2 GO:0090344 negative regulation of cell aging 2/719 28/18722 0.292434759471119 0.819413263437997 MIF/YBX1 2 GO:1903672 positive regulation of sprouting angiogenesis 2/719 28/18722 0.292434759471119 0.819413263437997 HMGB1/PKM 2 GO:1990776 response to angiotensin 2/719 28/18722 0.292434759471119 0.819413263437997 CDC6/CAV1 2 GO:0001666 response to hypoxia 14/719 307/18722 0.292925080560429 0.820190225569202 LDHA/ENO1/CHCHD2/CCNA2/PDLIM1/CCNB1/CD24/HSPD1/CAV1/PHB2/TXN2/PIN1/SLC29A1/BNIP3 14 GO:0044262 cellular carbohydrate metabolic process 13/719 283/18722 0.293571877203411 0.821403871535708 HMGB1/TPI1/PTGES3/PGAM1/IDH2/PPP1CA/PGP/PHLDA2/IMPA2/AKR1B1/ISYNA1/LCMT1/UGP2 13 GO:1903828 negative regulation of cellular protein localization 6/719 117/18722 0.293888537556992 0.821692715754842 TXN/CDT1/PARK7/SUMO1/ITGB1BP1/NSFL1C 6 GO:0001906 cell killing 9/719 188/18722 0.297353286439284 0.830776598542266 TUBB/TUBB4B/GAPDH/HMGN2/RPS19/PRDX1/RPL30/HSP90AB1/ROMO1 9 GO:0009749 response to glucose 10/719 212/18722 0.298285202909747 0.831157175120551 LDHA/PHPT1/DYNLL1/NME1/MPC2/ENY2/PIH1D1/TXN2/SLC29A1/ENSA 10 GO:0043523 regulation of neuron apoptotic process 10/719 212/18722 0.298285202909747 0.831157175120551 SOD1/PARK7/HSP90AB1/HSPD1/SET/PARP1/PIN1/NAE1/HRAS/BAX 10 GO:0032355 response to estradiol 7/719 141/18722 0.298460075386323 0.831157175120551 PCNA/GSTP1/CCNA2/GPX4/HNRNPD/EZH2/CCND1 7 GO:1904062 regulation of cation transmembrane transport 16/719 357/18722 0.298563907753977 0.831157175120551 CALM2/GSTO1/CALM1/YWHAH/PARK7/VDAC1/NDUFA4/YWHAE/COX17/CAV1/C4orf3/PPIF/PHB2/SUMO1/ISCU/BAX 16 GO:0046395 carboxylic acid catabolic process 11/719 236/18722 0.298568928101746 0.831157175120551 GCSH/ACAT2/ECHS1/ETFB/ECH1/ECI1/NUDT8/HADH/QPRT/ETFA/HSD17B10 11 GO:0070227 lymphocyte apoptotic process 4/719 72/18722 0.299124972852051 0.831502632115809 RPS6/AURKB/PRELID1/BAX 4 GO:1903036 positive regulation of response to wounding 4/719 72/18722 0.299124972852051 0.831502632115809 HMGB1/PRDX2/ACTG1/HRAS 4 GO:0051646 mitochondrion localization 3/719 50/18722 0.301229854018148 0.834478547581446 UBB/HSBP1/UXT 3 GO:0070231 T cell apoptotic process 3/719 50/18722 0.301229854018148 0.834478547581446 RPS6/PRELID1/BAX 3 GO:0006942 regulation of striated muscle contraction 5/719 95/18722 0.301279267828107 0.834478547581446 CALM2/GSTO1/CALM1/CAV1/C12orf57 5 GO:0032479 regulation of type I interferon production 5/719 95/18722 0.301279267828107 0.834478547581446 HMGB2/HMGB1/GAPDH/HSPD1/HSP90AA1 5 GO:0032606 type I interferon production 5/719 95/18722 0.301279267828107 0.834478547581446 HMGB2/HMGB1/GAPDH/HSPD1/HSP90AA1 5 GO:0009310 amine catabolic process 2/719 29/18722 0.306791619322465 0.840250159442107 COMT/ALDH7A1 2 GO:0019359 nicotinamide nucleotide biosynthetic process 2/719 29/18722 0.306791619322465 0.840250159442107 IDH2/QPRT 2 GO:0019363 pyridine nucleotide biosynthetic process 2/719 29/18722 0.306791619322465 0.840250159442107 IDH2/QPRT 2 GO:0021591 ventricular system development 2/719 29/18722 0.306791619322465 0.840250159442107 ANP32B/C12orf57 2 GO:0033028 myeloid cell apoptotic process 2/719 29/18722 0.306791619322465 0.840250159442107 CDKN2A/TCP1 2 GO:0042759 long-chain fatty acid biosynthetic process 2/719 29/18722 0.306791619322465 0.840250159442107 GSTP1/GPX4 2 GO:0051873 killing by host of symbiont cells 2/719 29/18722 0.306791619322465 0.840250159442107 GAPDH/ROMO1 2 GO:0051883 killing of cells in other organism involved in symbiotic interaction 2/719 29/18722 0.306791619322465 0.840250159442107 GAPDH/ROMO1 2 GO:1901017 negative regulation of potassium ion transmembrane transporter activity 2/719 29/18722 0.306791619322465 0.840250159442107 CAV1/SUMO1 2 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 4/719 73/18722 0.307840254919738 0.840250159442107 PHPT1/DYNLL1/MPC2/ENY2 4 GO:1904427 positive regulation of calcium ion transmembrane transport 4/719 73/18722 0.307840254919738 0.840250159442107 CALM2/GSTO1/CALM1/BAX 4 GO:0051259 protein complex oligomerization 11/719 238/18722 0.30798740742616 0.840250159442107 TK1/RRM2/ALDOA/MIF/RRM1/SSBP1/STOML2/ECT2/PRMT1/KRT10/HSD17B10 11 GO:0044242 cellular lipid catabolic process 10/719 214/18722 0.308231645572674 0.840250159442107 ACAT2/PRDX6/ECHS1/ETFB/ECH1/ECI1/NUDT8/HADH/ETFA/HSD17B10 10 GO:0044264 cellular polysaccharide metabolic process 5/719 96/18722 0.308831561262822 0.840250159442107 HMGB1/PTGES3/PPP1CA/PHLDA2/UGP2 5 GO:0032873 negative regulation of stress-activated MAPK cascade 3/719 51/18722 0.311833768306097 0.840250159442107 PPIA/GSTP1/PBK 3 GO:0051339 regulation of lyase activity 3/719 51/18722 0.311833768306097 0.840250159442107 PHPT1/PARK7/ISCU 3 GO:0065002 intracellular protein transmembrane transport 3/719 51/18722 0.311833768306097 0.840250159442107 HSPD1/ROMO1/TOMM40 3 GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 3/719 51/18722 0.311833768306097 0.840250159442107 PPIA/GSTP1/PBK 3 GO:0009451 RNA modification 8/719 167/18722 0.312514623619626 0.840250159442107 TRMT112/NHP2/TPRKB/SSB/METTL5/FBL/NOP10/HSD17B10 8 GO:0030218 erythrocyte differentiation 6/719 120/18722 0.314100117455899 0.840250159442107 HMGB2/SLC25A5/RPS6/RPS19/RPS14/PRMT1 6 GO:0032411 positive regulation of transporter activity 6/719 120/18722 0.314100117455899 0.840250159442107 CALM2/GSTO1/CALM1/PARK7/NDUFA4/COX17 6 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 5/719 97/18722 0.316410122133934 0.840250159442107 HMGB2/PRDX2/GSTP1/PARK7/FAIM 5 GO:0002437 inflammatory response to antigenic stimulus 4/719 74/18722 0.316580586004468 0.840250159442107 HMGB2/HMGB1/PARK7/PSMB4 4 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 4/719 74/18722 0.316580586004468 0.840250159442107 PARK7/PHB/PARP1/PHB2 4 GO:0033135 regulation of peptidyl-serine phosphorylation 7/719 144/18722 0.316910945495606 0.840250159442107 TXN/MIF/PARK7/HSP90AB1/HSP90AA1/CAV1/BAX 7 GO:0016054 organic acid catabolic process 11/719 240/18722 0.317479049642596 0.840250159442107 GCSH/ACAT2/ECHS1/ETFB/ECH1/ECI1/NUDT8/HADH/QPRT/ETFA/HSD17B10 11 GO:0032886 regulation of microtubule-based process 11/719 240/18722 0.317479049642596 0.840250159442107 STMN1/NPM1/RPS3/TPX2/SKA2/AURKA/ARL2/CKAP2/CFAP20/MKKS/CDK2AP2 11 GO:0006921 cellular component disassembly involved in execution phase of apoptosis 2/719 30/18722 0.321090876622651 0.840250159442107 TOP2A/BAX 2 GO:0007202 activation of phospholipase C activity 2/719 30/18722 0.321090876622651 0.840250159442107 PHB/PHB2 2 GO:0009072 aromatic amino acid family metabolic process 2/719 30/18722 0.321090876622651 0.840250159442107 PARK7/PCBD1 2 GO:0010800 positive regulation of peptidyl-threonine phosphorylation 2/719 30/18722 0.321090876622651 0.840250159442107 CALM2/CALM1 2 GO:0033137 negative regulation of peptidyl-serine phosphorylation 2/719 30/18722 0.321090876622651 0.840250159442107 CAV1/BAX 2 GO:0034390 smooth muscle cell apoptotic process 2/719 30/18722 0.321090876622651 0.840250159442107 CDKN2A/DNMT1 2 GO:0034391 regulation of smooth muscle cell apoptotic process 2/719 30/18722 0.321090876622651 0.840250159442107 CDKN2A/DNMT1 2 GO:0044030 regulation of DNA methylation 2/719 30/18722 0.321090876622651 0.840250159442107 MIS18A/PARP1 2 GO:0045948 positive regulation of translational initiation 2/719 30/18722 0.321090876622651 0.840250159442107 POLR2G/CDC123 2 GO:0048147 negative regulation of fibroblast proliferation 2/719 30/18722 0.321090876622651 0.840250159442107 GSTP1/BAX 2 GO:0090314 positive regulation of protein targeting to membrane 2/719 30/18722 0.321090876622651 0.840250159442107 HRAS/ITGB1BP1 2 GO:1903579 negative regulation of ATP metabolic process 2/719 30/18722 0.321090876622651 0.840250159442107 PPIF/PARP1 2 GO:0002218 activation of innate immune response 3/719 52/18722 0.322447256355387 0.840250159442107 HMGB1/HSP90AA1/XRCC6 3 GO:0043392 negative regulation of DNA binding 3/719 52/18722 0.322447256355387 0.840250159442107 MDFI/SUMO1/ID1 3 GO:0045010 actin nucleation 3/719 52/18722 0.322447256355387 0.840250159442107 ARPC1A/ARPC5/ARPC5L 3 GO:0051496 positive regulation of stress fiber assembly 3/719 52/18722 0.322447256355387 0.840250159442107 S100A10/RHOC/ITGB1BP1 3 GO:1903426 regulation of reactive oxygen species biosynthetic process 3/719 52/18722 0.322447256355387 0.840250159442107 PAGE4/PARK7/HSPD1 3 GO:0021543 pallium development 8/719 169/18722 0.323957196053275 0.840250159442107 UQCRQ/NME1/ANXA3/EZH2/ATIC/MKKS/BNIP3/BAX 8 GO:0000338 protein deneddylation 1/719 10/18722 0.324096490070527 0.840250159442107 COPS3 1 GO:0006222 UMP biosynthetic process 1/719 10/18722 0.324096490070527 0.840250159442107 UMPS 1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 1/719 10/18722 0.324096490070527 0.840250159442107 TSEN34 1 GO:0006735 NADH regeneration 1/719 10/18722 0.324096490070527 0.840250159442107 ENO1 1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway 1/719 10/18722 0.324096490070527 0.840250159442107 GNAS 1 GO:0009169 purine ribonucleoside monophosphate catabolic process 1/719 10/18722 0.324096490070527 0.840250159442107 PNP 1 GO:0009174 pyrimidine ribonucleoside monophosphate biosynthetic process 1/719 10/18722 0.324096490070527 0.840250159442107 UMPS 1 GO:0009750 response to fructose 1/719 10/18722 0.324096490070527 0.840250159442107 KRT18 1 GO:0009950 dorsal/ventral axis specification 1/719 10/18722 0.324096490070527 0.840250159442107 MDFI 1 GO:0010944 negative regulation of transcription by competitive promoter binding 1/719 10/18722 0.324096490070527 0.840250159442107 PHB 1 GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation 1/719 10/18722 0.324096490070527 0.840250159442107 NPM1 1 GO:0019062 virion attachment to host cell 1/719 10/18722 0.324096490070527 0.840250159442107 HSP90AB1 1 GO:0019614 catechol-containing compound catabolic process 1/719 10/18722 0.324096490070527 0.840250159442107 COMT 1 GO:0021548 pons development 1/719 10/18722 0.324096490070527 0.840250159442107 UQCRQ 1 GO:0030388 fructose 1,6-bisphosphate metabolic process 1/719 10/18722 0.324096490070527 0.840250159442107 ALDOA 1 GO:0031125 rRNA 3'-end processing 1/719 10/18722 0.324096490070527 0.840250159442107 EXOSC8 1 GO:0031340 positive regulation of vesicle fusion 1/719 10/18722 0.324096490070527 0.840250159442107 ANXA2 1 GO:0031915 positive regulation of synaptic plasticity 1/719 10/18722 0.324096490070527 0.840250159442107 CDC20 1 GO:0032025 response to cobalt ion 1/719 10/18722 0.324096490070527 0.840250159442107 BNIP3 1 GO:0032380 regulation of intracellular sterol transport 1/719 10/18722 0.324096490070527 0.840250159442107 ANXA2 1 GO:0032383 regulation of intracellular cholesterol transport 1/719 10/18722 0.324096490070527 0.840250159442107 ANXA2 1 GO:0034756 regulation of iron ion transport 1/719 10/18722 0.324096490070527 0.840250159442107 ISCU 1 GO:0035520 monoubiquitinated protein deubiquitination 1/719 10/18722 0.324096490070527 0.840250159442107 USP1 1 GO:0035999 tetrahydrofolate interconversion 1/719 10/18722 0.324096490070527 0.840250159442107 TYMS 1 GO:0036363 transforming growth factor beta activation 1/719 10/18722 0.324096490070527 0.840250159442107 HSP90AB1 1 GO:0042424 catecholamine catabolic process 1/719 10/18722 0.324096490070527 0.840250159442107 COMT 1 GO:0044557 relaxation of smooth muscle 1/719 10/18722 0.324096490070527 0.840250159442107 SOD1 1 GO:0045898 regulation of RNA polymerase II transcription preinitiation complex assembly 1/719 10/18722 0.324096490070527 0.840250159442107 HMGB1 1 GO:0048241 epinephrine transport 1/719 10/18722 0.324096490070527 0.840250159442107 LY6E 1 GO:0051660 establishment of centrosome localization 1/719 10/18722 0.324096490070527 0.840250159442107 MAD2L1 1 GO:0060068 vagina development 1/719 10/18722 0.324096490070527 0.840250159442107 BAX 1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus 1/719 10/18722 0.324096490070527 0.840250159442107 ENY2 1 GO:0061621 canonical glycolysis 1/719 10/18722 0.324096490070527 0.840250159442107 ENO1 1 GO:0061718 glucose catabolic process to pyruvate 1/719 10/18722 0.324096490070527 0.840250159442107 ENO1 1 GO:0097250 mitochondrial respirasome assembly 1/719 10/18722 0.324096490070527 0.840250159442107 COX7A2 1 GO:0097278 complement-dependent cytotoxicity 1/719 10/18722 0.324096490070527 0.840250159442107 HSP90AB1 1 GO:0098885 modification of postsynaptic actin cytoskeleton 1/719 10/18722 0.324096490070527 0.840250159442107 PFN1 1 GO:0098903 regulation of membrane repolarization during action potential 1/719 10/18722 0.324096490070527 0.840250159442107 CAV1 1 GO:0099171 presynaptic modulation of chemical synaptic transmission 1/719 10/18722 0.324096490070527 0.840250159442107 RPL22 1 GO:0099639 neurotransmitter receptor transport, endosome to plasma membrane 1/719 10/18722 0.324096490070527 0.840250159442107 NSG1 1 GO:1901978 positive regulation of cell cycle checkpoint 1/719 10/18722 0.324096490070527 0.840250159442107 MAD2L1 1 GO:1904779 regulation of protein localization to centrosome 1/719 10/18722 0.324096490070527 0.840250159442107 NSFL1C 1 GO:2000121 regulation of removal of superoxide radicals 1/719 10/18722 0.324096490070527 0.840250159442107 DHFR 1 GO:2000169 regulation of peptidyl-cysteine S-nitrosylation 1/719 10/18722 0.324096490070527 0.840250159442107 TXN 1 GO:2000234 positive regulation of rRNA processing 1/719 10/18722 0.324096490070527 0.840250159442107 TRMT112 1 GO:2000253 positive regulation of feeding behavior 1/719 10/18722 0.324096490070527 0.840250159442107 CFAP20 1 GO:2000425 regulation of apoptotic cell clearance 1/719 10/18722 0.324096490070527 0.840250159442107 HMGB1 1 GO:2000510 positive regulation of dendritic cell chemotaxis 1/719 10/18722 0.324096490070527 0.840250159442107 C1QBP 1 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 1/719 10/18722 0.324096490070527 0.840250159442107 PPP1CA 1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 1/719 10/18722 0.324096490070527 0.840250159442107 BAX 1 GO:0032412 regulation of ion transmembrane transporter activity 12/719 267/18722 0.330032539551628 0.853013241400635 CALM2/GSTO1/CALM1/YWHAH/NDUFA4/YWHAE/COX17/CAV1/C4orf3/PPIF/PHB2/SUMO1 12 GO:0033209 tumor necrosis factor-mediated signaling pathway 5/719 99/18722 0.331632758077218 0.853013241400635 GSTP1/KRT8/KRT18/EIF5A/TXNDC17 5 GO:0007566 embryo implantation 3/719 53/18722 0.333061972317596 0.853013241400635 RPL29/SOD1/C1QBP 3 GO:0031279 regulation of cyclase activity 3/719 53/18722 0.333061972317596 0.853013241400635 CALM2/CALM1/GNAS 3 GO:0008652 cellular amino acid biosynthetic process 4/719 76/18722 0.334116417480808 0.853013241400635 DHFR/PARK7/ADI1/PCBD1 4 GO:0030705 cytoskeleton-dependent intracellular transport 9/719 195/18722 0.33468326956611 0.853013241400635 TUBA1B/TUBB/TUBA1C/SOD1/UBB/HSBP1/HSPB11/UXT/SSNA1 9 GO:0001516 prostaglandin biosynthetic process 2/719 31/18722 0.335315797664153 0.853013241400635 MIF/PTGES3 2 GO:0006301 postreplication repair 2/719 31/18722 0.335315797664153 0.853013241400635 PCNA/UBE2N 2 GO:0006613 cotranslational protein targeting to membrane 2/719 31/18722 0.335315797664153 0.853013241400635 SRP14/SRP9 2 GO:0031114 regulation of microtubule depolymerization 2/719 31/18722 0.335315797664153 0.853013241400635 TPX2/CKAP2 2 GO:0034656 nucleobase-containing small molecule catabolic process 2/719 31/18722 0.335315797664153 0.853013241400635 NUDT1/PNP 2 GO:0036474 cell death in response to hydrogen peroxide 2/719 31/18722 0.335315797664153 0.853013241400635 TXN/PARK7 2 GO:0036475 neuron death in response to oxidative stress 2/719 31/18722 0.335315797664153 0.853013241400635 PARK7/PARP1 2 GO:0046457 prostanoid biosynthetic process 2/719 31/18722 0.335315797664153 0.853013241400635 MIF/PTGES3 2 GO:0051569 regulation of histone H3-K4 methylation 2/719 31/18722 0.335315797664153 0.853013241400635 PIH1D1/DNMT1 2 GO:0060045 positive regulation of cardiac muscle cell proliferation 2/719 31/18722 0.335315797664153 0.853013241400635 CDK1/CCNB1 2 GO:0071168 protein localization to chromatin 2/719 31/18722 0.335315797664153 0.853013241400635 EZH2/PIH1D1 2 GO:0051604 protein maturation 13/719 294/18722 0.341240363050435 0.853013241400635 ENO1/GCSH/BCL2L12/HSPD1/NDUFAB1/STOML2/NFU1/BAG2/SEC11A/PARP1/GLRX3/NAA10/METAP2 13 GO:0001678 cellular glucose homeostasis 8/719 172/18722 0.341256415097949 0.853013241400635 PHPT1/DYNLL1/NME1/NUCKS1/MPC2/ENY2/PIH1D1/SLC29A1 8 GO:0010508 positive regulation of autophagy 6/719 124/18722 0.341367769911106 0.853013241400635 HMGB1/SLC25A5/PARK7/VDAC1/PHB2/BNIP3 6 GO:0070507 regulation of microtubule cytoskeleton organization 7/719 148/18722 0.341805204668349 0.853013241400635 STMN1/RPS3/TPX2/SKA2/ARL2/CKAP2/CDK2AP2 7 GO:0055117 regulation of cardiac muscle contraction 4/719 77/18722 0.342902191575315 0.853013241400635 CALM2/GSTO1/CALM1/CAV1 4 GO:1901983 regulation of protein acetylation 4/719 77/18722 0.342902191575315 0.853013241400635 PARK7/SET/HINT2/PIH1D1 4 GO:0035065 regulation of histone acetylation 3/719 54/18722 0.343669887683727 0.853013241400635 PARK7/SET/PIH1D1 3 GO:0070228 regulation of lymphocyte apoptotic process 3/719 54/18722 0.343669887683727 0.853013241400635 AURKB/PRELID1/BAX 3 GO:0070839 metal ion export 3/719 54/18722 0.343669887683727 0.853013241400635 CALM2/CALM1/YWHAE 3 GO:0071248 cellular response to metal ion 9/719 197/18722 0.345502991198466 0.853013241400635 MT2A/CCNB1/SOD1/CACYBP/ECT2/PPIF/PARP1/SUMO1/BNIP3 9 GO:0006308 DNA catabolic process 2/719 32/18722 0.34945101542457 0.853013241400635 APEX1/BAX 2 GO:0010039 response to iron ion 2/719 32/18722 0.34945101542457 0.853013241400635 CCNB1/CCND1 2 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter 2/719 32/18722 0.34945101542457 0.853013241400635 EZH2/SUPT16H 2 GO:0051497 negative regulation of stress fiber assembly 2/719 32/18722 0.34945101542457 0.853013241400635 STMN1/PFN1 2 GO:0051642 centrosome localization 2/719 32/18722 0.34945101542457 0.853013241400635 MAD2L1/AURKA 2 GO:0072525 pyridine-containing compound biosynthetic process 2/719 32/18722 0.34945101542457 0.853013241400635 IDH2/QPRT 2 GO:0090140 regulation of mitochondrial fission 2/719 32/18722 0.34945101542457 0.853013241400635 AURKA/BNIP3 2 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation 1/719 11/18722 0.350067771795585 0.853013241400635 TSEN34 1 GO:0002357 defense response to tumor cell 1/719 11/18722 0.350067771795585 0.853013241400635 PRDX2 1 GO:0006002 fructose 6-phosphate metabolic process 1/719 11/18722 0.350067771795585 0.853013241400635 TALDO1 1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate 1/719 11/18722 0.350067771795585 0.853013241400635 MPC2 1 GO:0006449 regulation of translational termination 1/719 11/18722 0.350067771795585 0.853013241400635 EIF5A 1 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient 1/719 11/18722 0.350067771795585 0.853013241400635 BAX 1 GO:0010739 positive regulation of protein kinase A signaling 1/719 11/18722 0.350067771795585 0.853013241400635 MIF 1 GO:0010918 positive regulation of mitochondrial membrane potential 1/719 11/18722 0.350067771795585 0.853013241400635 STOML2 1 GO:0010986 positive regulation of lipoprotein particle clearance 1/719 11/18722 0.350067771795585 0.853013241400635 ANXA2 1 GO:0014820 tonic smooth muscle contraction 1/719 11/18722 0.350067771795585 0.853013241400635 MKKS 1 GO:0019048 modulation by virus of host process 1/719 11/18722 0.350067771795585 0.853013241400635 PHB2 1 GO:0019372 lipoxygenase pathway 1/719 11/18722 0.350067771795585 0.853013241400635 GPX4 1 GO:0021860 pyramidal neuron development 1/719 11/18722 0.350067771795585 0.853013241400635 UQCRQ 1 GO:0031442 positive regulation of mRNA 3'-end processing 1/719 11/18722 0.350067771795585 0.853013241400635 CCNB1 1 GO:0032377 regulation of intracellular lipid transport 1/719 11/18722 0.350067771795585 0.853013241400635 ANXA2 1 GO:0032610 interleukin-1 alpha production 1/719 11/18722 0.350067771795585 0.853013241400635 S100A13 1 GO:0032650 regulation of interleukin-1 alpha production 1/719 11/18722 0.350067771795585 0.853013241400635 S100A13 1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway 1/719 11/18722 0.350067771795585 0.853013241400635 PARP1 1 GO:0033197 response to vitamin E 1/719 11/18722 0.350067771795585 0.853013241400635 CCND1 1 GO:0033210 leptin-mediated signaling pathway 1/719 11/18722 0.350067771795585 0.853013241400635 MKKS 1 GO:0033234 negative regulation of protein sumoylation 1/719 11/18722 0.350067771795585 0.853013241400635 PARK7 1 GO:0033327 Leydig cell differentiation 1/719 11/18722 0.350067771795585 0.853013241400635 CCND1 1 GO:0033860 regulation of NAD(P)H oxidase activity 1/719 11/18722 0.350067771795585 0.853013241400635 PARK7 1 GO:0034163 regulation of toll-like receptor 9 signaling pathway 1/719 11/18722 0.350067771795585 0.853013241400635 HMGB1 1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' 1/719 11/18722 0.350067771795585 0.853013241400635 EXOSC8 1 GO:0034969 histone arginine methylation 1/719 11/18722 0.350067771795585 0.853013241400635 PRMT1 1 GO:0035246 peptidyl-arginine N-methylation 1/719 11/18722 0.350067771795585 0.853013241400635 PRMT1 1 GO:0035865 cellular response to potassium ion 1/719 11/18722 0.350067771795585 0.853013241400635 SOD1 1 GO:0039530 MDA-5 signaling pathway 1/719 11/18722 0.350067771795585 0.853013241400635 C1QBP 1 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 1/719 11/18722 0.350067771795585 0.853013241400635 C1QBP 1 GO:0042135 neurotransmitter catabolic process 1/719 11/18722 0.350067771795585 0.853013241400635 COMT 1 GO:0042416 dopamine biosynthetic process 1/719 11/18722 0.350067771795585 0.853013241400635 PARK7 1 GO:0043312 neutrophil degranulation 1/719 11/18722 0.350067771795585 0.853013241400635 ANXA3 1 GO:0044068 modulation by symbiont of host cellular process 1/719 11/18722 0.350067771795585 0.853013241400635 PHB2 1 GO:0044771 meiotic cell cycle phase transition 1/719 11/18722 0.350067771795585 0.853013241400635 CCNB2 1 GO:0045654 positive regulation of megakaryocyte differentiation 1/719 11/18722 0.350067771795585 0.853013241400635 HMGB2 1 GO:0046929 negative regulation of neurotransmitter secretion 1/719 11/18722 0.350067771795585 0.853013241400635 PNKD 1 GO:0048096 chromatin-mediated maintenance of transcription 1/719 11/18722 0.350067771795585 0.853013241400635 CDCA4 1 GO:0051081 nuclear membrane disassembly 1/719 11/18722 0.350067771795585 0.853013241400635 VRK1 1 GO:0070314 G1 to G0 transition 1/719 11/18722 0.350067771795585 0.853013241400635 EZH2 1 GO:0070341 fat cell proliferation 1/719 11/18722 0.350067771795585 0.853013241400635 TFDP1 1 GO:0070344 regulation of fat cell proliferation 1/719 11/18722 0.350067771795585 0.853013241400635 TFDP1 1 GO:0070475 rRNA base methylation 1/719 11/18722 0.350067771795585 0.853013241400635 TRMT112 1 GO:0070601 centromeric sister chromatid cohesion 1/719 11/18722 0.350067771795585 0.853013241400635 NAA10 1 GO:0071044 histone mRNA catabolic process 1/719 11/18722 0.350067771795585 0.853013241400635 SSB 1 GO:0072205 metanephric collecting duct development 1/719 11/18722 0.350067771795585 0.853013241400635 AKR1B1 1 GO:0072497 mesenchymal stem cell differentiation 1/719 11/18722 0.350067771795585 0.853013241400635 KRT18 1 GO:0090309 positive regulation of DNA methylation-dependent heterochromatin assembly 1/719 11/18722 0.350067771795585 0.853013241400635 DNMT1 1 GO:0090649 response to oxygen-glucose deprivation 1/719 11/18722 0.350067771795585 0.853013241400635 BNIP3 1 GO:1900112 regulation of histone H3-K9 trimethylation 1/719 11/18722 0.350067771795585 0.853013241400635 PIH1D1 1 GO:1902065 response to L-glutamate 1/719 11/18722 0.350067771795585 0.853013241400635 PCNA 1 GO:1902337 regulation of apoptotic process involved in morphogenesis 1/719 11/18722 0.350067771795585 0.853013241400635 BAX 1 GO:1902510 regulation of apoptotic DNA fragmentation 1/719 11/18722 0.350067771795585 0.853013241400635 BAX 1 GO:1902915 negative regulation of protein polyubiquitination 1/719 11/18722 0.350067771795585 0.853013241400635 PPIA 1 GO:1904181 positive regulation of membrane depolarization 1/719 11/18722 0.350067771795585 0.853013241400635 PARP1 1 GO:1904464 regulation of matrix metallopeptidase secretion 1/719 11/18722 0.350067771795585 0.853013241400635 IDH2 1 GO:1990773 matrix metallopeptidase secretion 1/719 11/18722 0.350067771795585 0.853013241400635 IDH2 1 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 1/719 11/18722 0.350067771795585 0.853013241400635 HMGB1 1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity 1/719 11/18722 0.350067771795585 0.853013241400635 PKIB 1 GO:2000615 regulation of histone H3-K9 acetylation 1/719 11/18722 0.350067771795585 0.853013241400635 PIH1D1 1 GO:2000644 regulation of receptor catabolic process 1/719 11/18722 0.350067771795585 0.853013241400635 ANXA2 1 GO:0019319 hexose biosynthetic process 4/719 78/18722 0.351693569288793 0.856432790488206 TPI1/PGP/AKR1B1/SLC25A1 4 GO:0031113 regulation of microtubule polymerization 3/719 55/18722 0.354263291059362 0.860707624511913 STMN1/RPS3/ARL2 3 GO:0042220 response to cocaine 3/719 55/18722 0.354263291059362 0.860707624511913 CCNA2/HSP90AB1/HSPD1 3 GO:0098900 regulation of action potential 3/719 55/18722 0.354263291059362 0.860707624511913 CALM1/CAV1/SUMO1 3 GO:0010522 regulation of calcium ion transport into cytosol 5/719 102/18722 0.354581786863723 0.860707624511913 CALM2/GSTO1/CALM1/CAV1/BAX 5 GO:0036293 response to decreased oxygen levels 14/719 322/18722 0.35561184059585 0.860707624511913 LDHA/ENO1/CHCHD2/CCNA2/PDLIM1/CCNB1/CD24/HSPD1/CAV1/PHB2/TXN2/PIN1/SLC29A1/BNIP3 14 GO:0070482 response to oxygen levels 15/719 347/18722 0.356425157211534 0.860707624511913 LDHA/ENO1/CHCHD2/CCNA2/PDLIM1/CCNB1/CD24/HSPD1/CAV1/CDK4/PHB2/TXN2/PIN1/SLC29A1/BNIP3 15 GO:0048511 rhythmic process 13/719 298/18722 0.358962340290824 0.860707624511913 TYMS/PCNA/CDK1/TOP2A/HNRNPD/PPP1CA/IMPDH2/CBX3/EZH2/CDK4/HNRNPR/ID1/ID3 13 GO:0001895 retina homeostasis 4/719 79/18722 0.360485965527044 0.860707624511913 PRDX1/ACTG1/SOD1/MKKS 4 GO:0032272 negative regulation of protein polymerization 4/719 79/18722 0.360485965527044 0.860707624511913 STMN1/PFN1/VDAC2/MKKS 4 GO:0051279 regulation of release of sequestered calcium ion into cytosol 4/719 79/18722 0.360485965527044 0.860707624511913 CALM2/GSTO1/CALM1/BAX 4 GO:0060420 regulation of heart growth 4/719 79/18722 0.360485965527044 0.860707624511913 CDK1/CCNB1/DUSP9/PIN1 4 GO:0071333 cellular response to glucose stimulus 7/719 151/18722 0.360633176921837 0.860707624511913 PHPT1/DYNLL1/NME1/MPC2/ENY2/PIH1D1/SLC29A1 7 GO:0071456 cellular response to hypoxia 7/719 151/18722 0.360633176921837 0.860707624511913 ENO1/CHCHD2/CCNA2/CCNB1/PHB2/SLC29A1/BNIP3 7 GO:0001881 receptor recycling 2/719 33/18722 0.363482449522251 0.860707624511913 ANXA2/NSG1 2 GO:0001975 response to amphetamine 2/719 33/18722 0.363482449522251 0.860707624511913 CALM1/SOD1 2 GO:0019362 pyridine nucleotide metabolic process 2/719 33/18722 0.363482449522251 0.860707624511913 IDH2/QPRT 2 GO:0031116 positive regulation of microtubule polymerization 2/719 33/18722 0.363482449522251 0.860707624511913 RPS3/ARL2 2 GO:0033198 response to ATP 2/719 33/18722 0.363482449522251 0.860707624511913 SOD1/HSPD1 2 GO:0036336 dendritic cell migration 2/719 33/18722 0.363482449522251 0.860707624511913 HMGB1/C1QBP 2 GO:0040020 regulation of meiotic nuclear division 2/719 33/18722 0.363482449522251 0.860707624511913 RAD51AP1/CDC20 2 GO:0045648 positive regulation of erythrocyte differentiation 2/719 33/18722 0.363482449522251 0.860707624511913 HMGB2/PRMT1 2 GO:0046496 nicotinamide nucleotide metabolic process 2/719 33/18722 0.363482449522251 0.860707624511913 IDH2/QPRT 2 GO:0071539 protein localization to centrosome 2/719 33/18722 0.363482449522251 0.860707624511913 AURKA/NSFL1C 2 GO:0150117 positive regulation of cell-substrate junction organization 2/719 33/18722 0.363482449522251 0.860707624511913 S100A10/ITGB1BP1 2 GO:1901380 negative regulation of potassium ion transmembrane transport 2/719 33/18722 0.363482449522251 0.860707624511913 CAV1/SUMO1 2 GO:0010518 positive regulation of phospholipase activity 3/719 56/18722 0.364834787039838 0.860707624511913 PHB/PHB2/HRAS 3 GO:0031529 ruffle organization 3/719 56/18722 0.364834787039838 0.860707624511913 PFN1/CAV1/HRAS 3 GO:0032608 interferon-beta production 3/719 56/18722 0.364834787039838 0.860707624511913 HMGB2/HMGB1/HSP90AA1 3 GO:0032648 regulation of interferon-beta production 3/719 56/18722 0.364834787039838 0.860707624511913 HMGB2/HMGB1/HSP90AA1 3 GO:0046622 positive regulation of organ growth 3/719 56/18722 0.364834787039838 0.860707624511913 CDK1/CCNB1/PIN1 3 GO:0070534 protein K63-linked ubiquitination 3/719 56/18722 0.364834787039838 0.860707624511913 UBE2T/UBE2S/UBE2N 3 GO:0098781 ncRNA transcription 3/719 56/18722 0.364834787039838 0.860707624511913 POLR2L/NCL/PIH1D1 3 GO:0048608 reproductive structure development 18/719 424/18722 0.365124101323799 0.860707624511913 HMGB2/NASP/RPS6/RRM1/KRT19/SOD1/KRT8/EIF2S2/UBB/HSP90AB1/PHLDA2/PRDX3/NUDT1/MEA1/CCND1/MDFI/MKKS/BAX 18 GO:0071453 cellular response to oxygen levels 8/719 177/18722 0.370355501277081 0.860707624511913 ENO1/CHCHD2/CCNA2/CCNB1/CAV1/PHB2/SLC29A1/BNIP3 8 GO:0016051 carbohydrate biosynthetic process 9/719 202/18722 0.372757882946679 0.860707624511913 TPI1/PTGES3/PPP1CA/PGP/IMPA2/AKR1B1/ISYNA1/UGP2/SLC25A1 9 GO:0071331 cellular response to hexose stimulus 7/719 153/18722 0.373233765135482 0.860707624511913 PHPT1/DYNLL1/NME1/MPC2/ENY2/PIH1D1/SLC29A1 7 GO:0000012 single strand break repair 1/719 12/18722 0.37504245364471 0.860707624511913 PARP1 1 GO:0001821 histamine secretion 1/719 12/18722 0.37504245364471 0.860707624511913 VAMP8 1 GO:0002182 cytoplasmic translational elongation 1/719 12/18722 0.37504245364471 0.860707624511913 RPLP2 1 GO:0002674 negative regulation of acute inflammatory response 1/719 12/18722 0.37504245364471 0.860707624511913 GSTP1 1 GO:0002863 positive regulation of inflammatory response to antigenic stimulus 1/719 12/18722 0.37504245364471 0.860707624511913 PARK7 1 GO:0002903 negative regulation of B cell apoptotic process 1/719 12/18722 0.37504245364471 0.860707624511913 AURKB 1 GO:0006285 base-excision repair, AP site formation 1/719 12/18722 0.37504245364471 0.860707624511913 UNG 1 GO:0007614 short-term memory 1/719 12/18722 0.37504245364471 0.860707624511913 COMT 1 GO:0009086 methionine biosynthetic process 1/719 12/18722 0.37504245364471 0.860707624511913 ADI1 1 GO:0010623 programmed cell death involved in cell development 1/719 12/18722 0.37504245364471 0.860707624511913 BAX 1 GO:0010826 negative regulation of centrosome duplication 1/719 12/18722 0.37504245364471 0.860707624511913 NPM1 1 GO:0030397 membrane disassembly 1/719 12/18722 0.37504245364471 0.860707624511913 VRK1 1 GO:0031126 sno(s)RNA 3'-end processing 1/719 12/18722 0.37504245364471 0.860707624511913 FBL 1 GO:0031453 positive regulation of heterochromatin assembly 1/719 12/18722 0.37504245364471 0.860707624511913 DNMT1 1 GO:0031953 negative regulation of protein autophosphorylation 1/719 12/18722 0.37504245364471 0.860707624511913 CAV1 1 GO:0033127 regulation of histone phosphorylation 1/719 12/18722 0.37504245364471 0.860707624511913 CCNB1 1 GO:0033235 positive regulation of protein sumoylation 1/719 12/18722 0.37504245364471 0.860707624511913 SAE1 1 GO:0034086 maintenance of sister chromatid cohesion 1/719 12/18722 0.37504245364471 0.860707624511913 NAA10 1 GO:0034088 maintenance of mitotic sister chromatid cohesion 1/719 12/18722 0.37504245364471 0.860707624511913 NAA10 1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway 1/719 12/18722 0.37504245364471 0.860707624511913 HMGB1 1 GO:0034392 negative regulation of smooth muscle cell apoptotic process 1/719 12/18722 0.37504245364471 0.860707624511913 DNMT1 1 GO:0042118 endothelial cell activation 1/719 12/18722 0.37504245364471 0.860707624511913 PPIA 1 GO:0042762 regulation of sulfur metabolic process 1/719 12/18722 0.37504245364471 0.860707624511913 COMT 1 GO:0043696 dedifferentiation 1/719 12/18722 0.37504245364471 0.860707624511913 HNRNPD 1 GO:0043697 cell dedifferentiation 1/719 12/18722 0.37504245364471 0.860707624511913 HNRNPD 1 GO:0044650 adhesion of symbiont to host cell 1/719 12/18722 0.37504245364471 0.860707624511913 HSP90AB1 1 GO:0045602 negative regulation of endothelial cell differentiation 1/719 12/18722 0.37504245364471 0.860707624511913 ID1 1 GO:0045605 negative regulation of epidermal cell differentiation 1/719 12/18722 0.37504245364471 0.860707624511913 EZH2 1 GO:0045683 negative regulation of epidermis development 1/719 12/18722 0.37504245364471 0.860707624511913 EZH2 1 GO:0046606 negative regulation of centrosome cycle 1/719 12/18722 0.37504245364471 0.860707624511913 NPM1 1 GO:0048548 regulation of pinocytosis 1/719 12/18722 0.37504245364471 0.860707624511913 CAV1 1 GO:0051001 negative regulation of nitric-oxide synthase activity 1/719 12/18722 0.37504245364471 0.860707624511913 CAV1 1 GO:0051095 regulation of helicase activity 1/719 12/18722 0.37504245364471 0.860707624511913 SSBP1 1 GO:0051583 dopamine uptake involved in synaptic transmission 1/719 12/18722 0.37504245364471 0.860707624511913 PARK7 1 GO:0051639 actin filament network formation 1/719 12/18722 0.37504245364471 0.860707624511913 ARPC5 1 GO:0051934 catecholamine uptake involved in synaptic transmission 1/719 12/18722 0.37504245364471 0.860707624511913 PARK7 1 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development 1/719 12/18722 0.37504245364471 0.860707624511913 PIN1 1 GO:0061620 glycolytic process through glucose-6-phosphate 1/719 12/18722 0.37504245364471 0.860707624511913 ENO1 1 GO:0070213 protein auto-ADP-ribosylation 1/719 12/18722 0.37504245364471 0.860707624511913 PARP1 1 GO:0070493 thrombin-activated receptor signaling pathway 1/719 12/18722 0.37504245364471 0.860707624511913 STMN1 1 GO:0072182 regulation of nephron tubule epithelial cell differentiation 1/719 12/18722 0.37504245364471 0.860707624511913 CD24 1 GO:0072520 seminiferous tubule development 1/719 12/18722 0.37504245364471 0.860707624511913 UBB 1 GO:0072584 caveolin-mediated endocytosis 1/719 12/18722 0.37504245364471 0.860707624511913 CAV1 1 GO:0072711 cellular response to hydroxyurea 1/719 12/18722 0.37504245364471 0.860707624511913 RAD51 1 GO:0090085 regulation of protein deubiquitination 1/719 12/18722 0.37504245364471 0.860707624511913 PARK7 1 GO:0090646 mitochondrial tRNA processing 1/719 12/18722 0.37504245364471 0.860707624511913 HSD17B10 1 GO:0090677 reversible differentiation 1/719 12/18722 0.37504245364471 0.860707624511913 DNMT1 1 GO:0098911 regulation of ventricular cardiac muscle cell action potential 1/719 12/18722 0.37504245364471 0.860707624511913 CAV1 1 GO:0098974 postsynaptic actin cytoskeleton organization 1/719 12/18722 0.37504245364471 0.860707624511913 ACTG1 1 GO:0120263 positive regulation of heterochromatin organization 1/719 12/18722 0.37504245364471 0.860707624511913 DNMT1 1 GO:1901298 regulation of hydrogen peroxide-mediated programmed cell death 1/719 12/18722 0.37504245364471 0.860707624511913 PARK7 1 GO:1901894 regulation of ATPase-coupled calcium transmembrane transporter activity 1/719 12/18722 0.37504245364471 0.860707624511913 C4orf3 1 GO:1903332 regulation of protein folding 1/719 12/18722 0.37504245364471 0.860707624511913 PDCD5 1 GO:1903624 regulation of DNA catabolic process 1/719 12/18722 0.37504245364471 0.860707624511913 BAX 1 GO:1904748 regulation of apoptotic process involved in development 1/719 12/18722 0.37504245364471 0.860707624511913 BAX 1 GO:1905214 regulation of RNA binding 1/719 12/18722 0.37504245364471 0.860707624511913 NUCKS1 1 GO:2000035 regulation of stem cell division 1/719 12/18722 0.37504245364471 0.860707624511913 CDK2AP2 1 GO:2000508 regulation of dendritic cell chemotaxis 1/719 12/18722 0.37504245364471 0.860707624511913 C1QBP 1 GO:2000628 regulation of miRNA metabolic process 1/719 12/18722 0.37504245364471 0.860707624511913 HRAS 1 GO:0030219 megakaryocyte differentiation 3/719 57/18722 0.375377294271819 0.860707624511913 HMGB2/EIF6/PRMT1 3 GO:1900024 regulation of substrate adhesion-dependent cell spreading 3/719 57/18722 0.375377294271819 0.860707624511913 S100A10/C1QBP/ITGB1BP1 3 GO:0010951 negative regulation of endopeptidase activity 11/719 252/18722 0.37560012848694 0.860707624511913 PTTG1/GAPDH/BIRC5/PEBP1/PARK7/ANXA2/PRDX5/BCL2L12/PRDX3/TRIAP1/PIH1D1 11 GO:0006109 regulation of carbohydrate metabolic process 8/719 178/18722 0.376202869472921 0.860707624511913 HMGB1/PGAM1/ARL2/PPP1CA/PGP/PHLDA2/EIF6/LCMT1 8 GO:0110053 regulation of actin filament organization 12/719 277/18722 0.37636559972711 0.860707624511913 STMN1/S100A10/PFN1/ACTG1/DSTN/ARPC1A/ARPC5/RHOC/ARPC5L/MKKS/ID1/ITGB1BP1 12 GO:0061458 reproductive system development 18/719 427/18722 0.376402256810396 0.860707624511913 HMGB2/NASP/RPS6/RRM1/KRT19/SOD1/KRT8/EIF2S2/UBB/HSP90AB1/PHLDA2/PRDX3/NUDT1/MEA1/CCND1/MDFI/MKKS/BAX 18 GO:0007095 mitotic G2 DNA damage checkpoint signaling 2/719 34/18722 0.377397230290544 0.860707624511913 CDK1/CLSPN 2 GO:0009303 rRNA transcription 2/719 34/18722 0.377397230290544 0.860707624511913 NCL/PIH1D1 2 GO:0010661 positive regulation of muscle cell apoptotic process 2/719 34/18722 0.377397230290544 0.860707624511913 CDKN2A/BNIP3 2 GO:0035308 negative regulation of protein dephosphorylation 2/719 34/18722 0.377397230290544 0.860707624511913 YWHAE/ENSA 2 GO:0043276 anoikis 2/719 34/18722 0.377397230290544 0.860707624511913 CAV1/TFDP1 2 GO:0051085 chaperone cofactor-dependent protein refolding 2/719 34/18722 0.377397230290544 0.860707624511913 HSPE1/PTGES3 2 GO:0040029 regulation of gene expression, epigenetic 5/719 105/18722 0.377593552675486 0.860707624511913 CDCA4/HELLS/EZH2/DNMT1/POLE3 5 GO:0007605 sensory perception of sound 7/719 154/18722 0.379543493309872 0.864129183467183 BIRC5/SOD1/TIMM8B/ALDH7A1/TIMM13/TIMM10/MKKS 7 GO:0071326 cellular response to monosaccharide stimulus 7/719 154/18722 0.379543493309872 0.864129183467183 PHPT1/DYNLL1/NME1/MPC2/ENY2/PIH1D1/SLC29A1 7 GO:0051346 negative regulation of hydrolase activity 16/719 379/18722 0.38501372914072 0.867029401370315 PTTG1/GAPDH/BIRC5/PEBP1/PARK7/ANXA2/PRDX5/BCL2L12/ARL2/PRDX3/TRIAP1/CNN3/PIH1D1/PPIF/MKKS/HRAS 16 GO:0035821 modulation of process of other organism 5/719 106/18722 0.385263981353307 0.867029401370315 NUCKS1/CFL1/PSMC3/PHB/PHB2 5 GO:0046620 regulation of organ growth 5/719 106/18722 0.385263981353307 0.867029401370315 CDK1/CCNB1/SOD1/DUSP9/PIN1 5 GO:0002931 response to ischemia 3/719 58/18722 0.385884042781658 0.867029401370315 HSPD1/CAV1/PPIF 3 GO:0086065 cell communication involved in cardiac conduction 3/719 58/18722 0.385884042781658 0.867029401370315 CALM2/CALM1/CAV1 3 GO:0001892 embryonic placenta development 4/719 82/18722 0.386825172115584 0.867029401370315 KRT19/KRT8/PHLDA2/MDFI 4 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 4/719 82/18722 0.386825172115584 0.867029401370315 HMGB2/PARK7/FAIM/BAX 4 GO:0046364 monosaccharide biosynthetic process 4/719 82/18722 0.386825172115584 0.867029401370315 TPI1/PGP/AKR1B1/SLC25A1 4 GO:0006612 protein targeting to membrane 6/719 131/18722 0.389545334500552 0.867029401370315 NACA/SRP14/SRP9/HRAS/ITGB1BP1/ZDHHC12 6 GO:0006084 acetyl-CoA metabolic process 2/719 35/18722 0.391183626773067 0.867029401370315 MPC2/NUDT8 2 GO:0032205 negative regulation of telomere maintenance 2/719 35/18722 0.391183626773067 0.867029401370315 HNRNPA1/PARP1 2 GO:0032232 negative regulation of actin filament bundle assembly 2/719 35/18722 0.391183626773067 0.867029401370315 STMN1/PFN1 2 GO:0033146 regulation of intracellular estrogen receptor signaling pathway 2/719 35/18722 0.391183626773067 0.867029401370315 PARP1/PHB2 2 GO:0039694 viral RNA genome replication 2/719 35/18722 0.391183626773067 0.867029401370315 TOP2A/PHB 2 GO:0046471 phosphatidylglycerol metabolic process 2/719 35/18722 0.391183626773067 0.867029401370315 STOML2/PHB2 2 GO:0098810 neurotransmitter reuptake 2/719 35/18722 0.391183626773067 0.867029401370315 PARK7/SLC29A1 2 GO:1905508 protein localization to microtubule organizing center 2/719 35/18722 0.391183626773067 0.867029401370315 AURKA/NSFL1C 2 GO:1905898 positive regulation of response to endoplasmic reticulum stress 2/719 35/18722 0.391183626773067 0.867029401370315 CAV1/BAX 2 GO:0005976 polysaccharide metabolic process 5/719 107/18722 0.392929481778924 0.867029401370315 HMGB1/PTGES3/PPP1CA/PHLDA2/UGP2 5 GO:0001510 RNA methylation 4/719 83/18722 0.395578149183251 0.867029401370315 TRMT112/METTL5/FBL/HSD17B10 4 GO:0051899 membrane depolarization 4/719 83/18722 0.395578149183251 0.867029401370315 YWHAH/PARK7/CAV1/PARP1 4 GO:0051568 histone H3-K4 methylation 3/719 59/18722 0.396348570645428 0.867029401370315 PIH1D1/DPY30/DNMT1 3 GO:0071806 protein transmembrane transport 3/719 59/18722 0.396348570645428 0.867029401370315 HSPD1/ROMO1/TOMM40 3 GO:0032956 regulation of actin cytoskeleton organization 15/719 357/18722 0.397917991601455 0.867029401370315 STMN1/S100A10/PFN1/PHPT1/ACTG1/DSTN/ARPC1A/ARPC5/ECT2/RHOC/ARPC5L/MKKS/HRAS/ID1/ITGB1BP1 15 GO:1990845 adaptive thermogenesis 7/719 157/18722 0.398490292058641 0.867029401370315 SLC25A5/GNAS/CAV1/HADH/RHEB/FH/ID1 7 GO:0006361 transcription initiation from RNA polymerase I promoter 1/719 13/18722 0.399058727072259 0.867029401370315 PIH1D1 1 GO:0007183 SMAD protein complex assembly 1/719 13/18722 0.399058727072259 0.867029401370315 PARP1 1 GO:0009134 nucleoside diphosphate catabolic process 1/719 13/18722 0.399058727072259 0.867029401370315 NUDT5 1 GO:0009650 UV protection 1/719 13/18722 0.399058727072259 0.867029401370315 FEN1 1 GO:0010635 regulation of mitochondrial fusion 1/719 13/18722 0.399058727072259 0.867029401370315 BNIP3 1 GO:0010755 regulation of plasminogen activation 1/719 13/18722 0.399058727072259 0.867029401370315 ENO1 1 GO:0016078 tRNA catabolic process 1/719 13/18722 0.399058727072259 0.867029401370315 EXOSC8 1 GO:0018095 protein polyglutamylation 1/719 13/18722 0.399058727072259 0.867029401370315 CFAP20 1 GO:0018206 peptidyl-methionine modification 1/719 13/18722 0.399058727072259 0.867029401370315 METAP2 1 GO:0019336 phenol-containing compound catabolic process 1/719 13/18722 0.399058727072259 0.867029401370315 COMT 1 GO:0021554 optic nerve development 1/719 13/18722 0.399058727072259 0.867029401370315 RPL24 1 GO:0021794 thalamus development 1/719 13/18722 0.399058727072259 0.867029401370315 UQCRQ 1 GO:0021859 pyramidal neuron differentiation 1/719 13/18722 0.399058727072259 0.867029401370315 UQCRQ 1 GO:0030836 positive regulation of actin filament depolymerization 1/719 13/18722 0.399058727072259 0.867029401370315 DSTN 1 GO:0031053 primary miRNA processing 1/719 13/18722 0.399058727072259 0.867029401370315 HNRNPA2B1 1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 1/719 13/18722 0.399058727072259 0.867029401370315 PRDX2 1 GO:0032042 mitochondrial DNA metabolic process 1/719 13/18722 0.399058727072259 0.867029401370315 PARP1 1 GO:0032230 positive regulation of synaptic transmission, GABAergic 1/719 13/18722 0.399058727072259 0.867029401370315 ZDHHC12 1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter 1/719 13/18722 0.399058727072259 0.867029401370315 SUPT16H 1 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway 1/719 13/18722 0.399058727072259 0.867029401370315 PARP1 1 GO:0033262 regulation of nuclear cell cycle DNA replication 1/719 13/18722 0.399058727072259 0.867029401370315 CDT1 1 GO:0034135 regulation of toll-like receptor 2 signaling pathway 1/719 13/18722 0.399058727072259 0.867029401370315 HMGB1 1 GO:0034309 primary alcohol biosynthetic process 1/719 13/18722 0.399058727072259 0.867029401370315 PARK7 1 GO:0034982 mitochondrial protein processing 1/719 13/18722 0.399058727072259 0.867029401370315 STOML2 1 GO:0036462 TRAIL-activated apoptotic signaling pathway 1/719 13/18722 0.399058727072259 0.867029401370315 PARK7 1 GO:0042308 negative regulation of protein import into nucleus 1/719 13/18722 0.399058727072259 0.867029401370315 SUMO1 1 GO:0042541 hemoglobin biosynthetic process 1/719 13/18722 0.399058727072259 0.867029401370315 PRMT1 1 GO:0043247 telomere maintenance in response to DNA damage 1/719 13/18722 0.399058727072259 0.867029401370315 APEX1 1 GO:0043928 exonucleolytic catabolism of deadenylated mRNA 1/719 13/18722 0.399058727072259 0.867029401370315 EXOSC8 1 GO:0043970 histone H3-K9 acetylation 1/719 13/18722 0.399058727072259 0.867029401370315 PIH1D1 1 GO:0044090 positive regulation of vacuole organization 1/719 13/18722 0.399058727072259 0.867029401370315 ANXA2 1 GO:0046415 urate metabolic process 1/719 13/18722 0.399058727072259 0.867029401370315 PNP 1 GO:0046689 response to mercury ion 1/719 13/18722 0.399058727072259 0.867029401370315 PARK7 1 GO:0048012 hepatocyte growth factor receptor signaling pathway 1/719 13/18722 0.399058727072259 0.867029401370315 STMN1 1 GO:0048070 regulation of developmental pigmentation 1/719 13/18722 0.399058727072259 0.867029401370315 BAX 1 GO:0051451 myoblast migration 1/719 13/18722 0.399058727072259 0.867029401370315 ITGB1BP1 1 GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1/719 13/18722 0.399058727072259 0.867029401370315 POLR2G 1 GO:0060707 trophoblast giant cell differentiation 1/719 13/18722 0.399058727072259 0.867029401370315 MDFI 1 GO:0061615 glycolytic process through fructose-6-phosphate 1/719 13/18722 0.399058727072259 0.867029401370315 ENO1 1 GO:0061744 motor behavior 1/719 13/18722 0.399058727072259 0.867029401370315 C12orf57 1 GO:0070234 positive regulation of T cell apoptotic process 1/719 13/18722 0.399058727072259 0.867029401370315 PRELID1 1 GO:0070254 mucus secretion 1/719 13/18722 0.399058727072259 0.867029401370315 VAMP8 1 GO:0070914 UV-damage excision repair 1/719 13/18722 0.399058727072259 0.867029401370315 POLD3 1 GO:0071027 nuclear RNA surveillance 1/719 13/18722 0.399058727072259 0.867029401370315 EXOSC8 1 GO:0071028 nuclear mRNA surveillance 1/719 13/18722 0.399058727072259 0.867029401370315 EXOSC8 1 GO:0072710 response to hydroxyurea 1/719 13/18722 0.399058727072259 0.867029401370315 RAD51 1 GO:0098814 spontaneous synaptic transmission 1/719 13/18722 0.399058727072259 0.867029401370315 NSG1 1 GO:0120305 regulation of pigmentation 1/719 13/18722 0.399058727072259 0.867029401370315 BAX 1 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response 1/719 13/18722 0.399058727072259 0.867029401370315 BAX 1 GO:1902260 negative regulation of delayed rectifier potassium channel activity 1/719 13/18722 0.399058727072259 0.867029401370315 SUMO1 1 GO:1904590 negative regulation of protein import 1/719 13/18722 0.399058727072259 0.867029401370315 SUMO1 1 GO:1905064 negative regulation of vascular associated smooth muscle cell differentiation 1/719 13/18722 0.399058727072259 0.867029401370315 DNMT1 1 GO:1905269 positive regulation of chromatin organization 1/719 13/18722 0.399058727072259 0.867029401370315 DNMT1 1 GO:1990403 embryonic brain development 1/719 13/18722 0.399058727072259 0.867029401370315 RPL10 1 GO:2001023 regulation of response to drug 1/719 13/18722 0.399058727072259 0.867029401370315 ADIRF 1 GO:2001198 regulation of dendritic cell differentiation 1/719 13/18722 0.399058727072259 0.867029401370315 HMGB1 1 GO:0060401 cytosolic calcium ion transport 8/719 182/18722 0.399638871545571 0.867800144078086 CALM2/GSTO1/CALM1/VDAC1/YWHAE/CAV1/BAX/MCUR1 8 GO:0032271 regulation of protein polymerization 10/719 232/18722 0.400338478020845 0.86882927868109 STMN1/RPS3/PFN1/ARL2/HSP90AA1/ARPC1A/VDAC2/ARPC5/ARPC5L/MKKS 10 GO:0006970 response to osmotic stress 4/719 84/18722 0.40431100365489 0.873654297667114 HSP90AB1/XRCC6/AKR1B1/BAX 4 GO:0010921 regulation of phosphatase activity 4/719 84/18722 0.40431100365489 0.873654297667114 CALM2/CALM1/HSP90AB1/CSNK2B 4 GO:0042440 pigment metabolic process 4/719 84/18722 0.40431100365489 0.873654297667114 PAICS/GMPS/DDT/APRT 4 GO:0061157 mRNA destabilization 4/719 84/18722 0.40431100365489 0.873654297667114 HNRNPD/EXOSC8/POLR2G/HNRNPR 4 GO:0003352 regulation of cilium movement 2/719 36/18722 0.404830978451463 0.873654297667114 CFAP20/MKKS 2 GO:0008207 C21-steroid hormone metabolic process 2/719 36/18722 0.404830978451463 0.873654297667114 AKR1B1/HSD17B10 2 GO:0045738 negative regulation of DNA repair 2/719 36/18722 0.404830978451463 0.873654297667114 RPS3/RMI2 2 GO:0090313 regulation of protein targeting to membrane 2/719 36/18722 0.404830978451463 0.873654297667114 HRAS/ITGB1BP1 2 GO:1901658 glycosyl compound catabolic process 2/719 36/18722 0.404830978451463 0.873654297667114 NUDT1/PNP 2 GO:1903539 protein localization to postsynaptic membrane 2/719 36/18722 0.404830978451463 0.873654297667114 NSG1/HRAS 2 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 3/719 60/18722 0.406764720070168 0.876167271934801 C1QBP/PHB/PHB2 3 GO:0062012 regulation of small molecule metabolic process 14/719 334/18722 0.407329918831538 0.876167271934801 HMGB1/ENO1/SOD1/PARK7/PGAM1/COMT/ARL2/PPP1CA/PGP/PHLDA2/CAV1/EIF6/LCMT1/PARP1 14 GO:0032414 positive regulation of ion transmembrane transporter activity 5/719 109/18722 0.408234480014649 0.876167271934801 CALM2/GSTO1/CALM1/NDUFA4/COX17 5 GO:0006520 cellular amino acid metabolic process 12/719 284/18722 0.409241057505537 0.876167271934801 GCSH/DHFR/PARK7/COMT/ECHS1/GMPS/ADI1/SMS/PCBD1/NIT2/HSD17B10/PTS 12 GO:0061041 regulation of wound healing 6/719 134/18722 0.41021659227918 0.876167271934801 HMGB1/PRDX2/ACTG1/ANXA2/CAV1/HRAS 6 GO:1903169 regulation of calcium ion transmembrane transport 7/719 159/18722 0.411119791707398 0.876167271934801 CALM2/GSTO1/CALM1/VDAC1/YWHAE/C4orf3/BAX 7 GO:0032409 regulation of transporter activity 13/719 310/18722 0.412837620144382 0.876167271934801 CALM2/GSTO1/CALM1/YWHAH/PARK7/NDUFA4/YWHAE/COX17/CAV1/C4orf3/PPIF/PHB2/SUMO1 13 GO:0070997 neuron death 15/719 361/18722 0.414649659462739 0.876167271934801 GAPDH/SOD1/PARK7/UBB/HSP90AB1/HSPD1/SET/PSMC1/NENF/PARP1/PIN1/NAE1/HRAS/BNIP3/BAX 15 GO:0051091 positive regulation of DNA-binding transcription factor activity 11/719 260/18722 0.414986452668319 0.876167271934801 PPIA/NPM1/RPS3/PARK7/ANXA3/UBE2N/PRDX3/CAV1/PHB2/TFDP1/BUD31 11 GO:0014812 muscle cell migration 5/719 110/18722 0.41586852375966 0.876167271934801 GSTP1/S100A11/ARPC5/APEX1/ITGB1BP1 5 GO:1905954 positive regulation of lipid localization 5/719 110/18722 0.41586852375966 0.876167271934801 DBI/ANXA2/PRELID1/TRIAP1/CAV1 5 GO:0001101 response to acid chemical 6/719 135/18722 0.417094767079986 0.876167271934801 PCNA/GSTP1/KRT8/HNRNPD/AKR1B1/DNMT1 6 GO:0006900 vesicle budding from membrane 3/719 61/18722 0.41712663295102 0.876167271934801 S100A10/ANXA2/SNX3 3 GO:0019748 secondary metabolic process 3/719 61/18722 0.41712663295102 0.876167271934801 AKR7A2/AKR1B1/DDT 3 GO:0040014 regulation of multicellular organism growth 3/719 61/18722 0.41712663295102 0.876167271934801 SOD1/CDK4/MKKS 3 GO:0043966 histone H3 acetylation 3/719 61/18722 0.41712663295102 0.876167271934801 PIH1D1/TAF9/POLE3 3 GO:0043433 negative regulation of DNA-binding transcription factor activity 8/719 185/18722 0.417227744251259 0.876167271934801 PRDX2/EZH2/CDKN2A/MDFI/PHB2/SUMO1/ID1/ID3 8 GO:0051896 regulation of protein kinase B signaling 8/719 185/18722 0.417227744251259 0.876167271934801 TXN/PARK7/HSP90AB1/C1QBP/HSP90AA1/PHLDA3/PHB/ITGB1BP1 8 GO:0031112 positive regulation of microtubule polymerization or depolymerization 2/719 37/18722 0.418329630525786 0.876167271934801 RPS3/ARL2 2 GO:0032570 response to progesterone 2/719 37/18722 0.418329630525786 0.876167271934801 TYMS/CAV1 2 GO:0042178 xenobiotic catabolic process 2/719 37/18722 0.418329630525786 0.876167271934801 GSTO1/NUDT15 2 GO:0051567 histone H3-K9 methylation 2/719 37/18722 0.418329630525786 0.876167271934801 PIH1D1/DNMT1 2 GO:0060306 regulation of membrane repolarization 2/719 37/18722 0.418329630525786 0.876167271934801 YWHAE/CAV1 2 GO:0062237 protein localization to postsynapse 2/719 37/18722 0.418329630525786 0.876167271934801 NSG1/HRAS 2 GO:0090305 nucleic acid phosphodiester bond hydrolysis 11/719 261/18722 0.419920531054617 0.876167271934801 FEN1/RNASEH2A/NHP2/EXOSC8/POP7/POLR3K/TSEN34/POLR2I/RPP30/APEX1/BAX 11 GO:0000209 protein polyubiquitination 10/719 236/18722 0.421105537828453 0.876167271934801 UBE2C/UBE2T/PPIA/ANAPC11/UBE2S/RBX1/UBE2L3/UBE2N/SKP1/DDA1 10 GO:0002864 regulation of acute inflammatory response to antigenic stimulus 1/719 14/18722 0.422153321932222 0.876167271934801 PARK7 1 GO:0006465 signal peptide processing 1/719 14/18722 0.422153321932222 0.876167271934801 SEC11A 1 GO:0009071 serine family amino acid catabolic process 1/719 14/18722 0.422153321932222 0.876167271934801 GCSH 1 GO:0009158 ribonucleoside monophosphate catabolic process 1/719 14/18722 0.422153321932222 0.876167271934801 PNP 1 GO:0009173 pyrimidine ribonucleoside monophosphate metabolic process 1/719 14/18722 0.422153321932222 0.876167271934801 UMPS 1 GO:0010421 hydrogen peroxide-mediated programmed cell death 1/719 14/18722 0.422153321932222 0.876167271934801 PARK7 1 GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1/719 14/18722 0.422153321932222 0.876167271934801 ITGB1BP1 1 GO:0018158 protein oxidation 1/719 14/18722 0.422153321932222 0.876167271934801 PRDX3 1 GO:0022038 corpus callosum development 1/719 14/18722 0.422153321932222 0.876167271934801 C12orf57 1 GO:0030049 muscle filament sliding 1/719 14/18722 0.422153321932222 0.876167271934801 MYL6 1 GO:0031115 negative regulation of microtubule polymerization 1/719 14/18722 0.422153321932222 0.876167271934801 STMN1 1 GO:0033008 positive regulation of mast cell activation involved in immune response 1/719 14/18722 0.422153321932222 0.876167271934801 VAMP8 1 GO:0033212 iron import into cell 1/719 14/18722 0.422153321932222 0.876167271934801 ISCU 1 GO:0036151 phosphatidylcholine acyl-chain remodeling 1/719 14/18722 0.422153321932222 0.876167271934801 DBI 1 GO:0036295 cellular response to increased oxygen levels 1/719 14/18722 0.422153321932222 0.876167271934801 CAV1 1 GO:0038166 angiotensin-activated signaling pathway 1/719 14/18722 0.422153321932222 0.876167271934801 CAV1 1 GO:0043144 sno(s)RNA processing 1/719 14/18722 0.422153321932222 0.876167271934801 FBL 1 GO:0043306 positive regulation of mast cell degranulation 1/719 14/18722 0.422153321932222 0.876167271934801 VAMP8 1 GO:0044764 multi-organism cellular process 1/719 14/18722 0.422153321932222 0.876167271934801 CAV1 1 GO:0045989 positive regulation of striated muscle contraction 1/719 14/18722 0.422153321932222 0.876167271934801 GSTO1 1 GO:0046049 UMP metabolic process 1/719 14/18722 0.422153321932222 0.876167271934801 UMPS 1 GO:0046655 folic acid metabolic process 1/719 14/18722 0.422153321932222 0.876167271934801 DHFR 1 GO:0048291 isotype switching to IgG isotypes 1/719 14/18722 0.422153321932222 0.876167271934801 HSPD1 1 GO:0050667 homocysteine metabolic process 1/719 14/18722 0.422153321932222 0.876167271934801 COMT 1 GO:0051589 negative regulation of neurotransmitter transport 1/719 14/18722 0.422153321932222 0.876167271934801 PNKD 1 GO:0060081 membrane hyperpolarization 1/719 14/18722 0.422153321932222 0.876167271934801 PARK7 1 GO:0060088 auditory receptor cell stereocilium organization 1/719 14/18722 0.422153321932222 0.876167271934801 SOD1 1 GO:0060576 intestinal epithelial cell development 1/719 14/18722 0.422153321932222 0.876167271934801 TYMS 1 GO:0061709 reticulophagy 1/719 14/18722 0.422153321932222 0.876167271934801 UFC1 1 GO:0070141 response to UV-A 1/719 14/18722 0.422153321932222 0.876167271934801 CCND1 1 GO:0070986 left/right axis specification 1/719 14/18722 0.422153321932222 0.876167271934801 HSPB11 1 GO:0072160 nephron tubule epithelial cell differentiation 1/719 14/18722 0.422153321932222 0.876167271934801 CD24 1 GO:0072350 tricarboxylic acid metabolic process 1/719 14/18722 0.422153321932222 0.876167271934801 IDH2 1 GO:0072531 pyrimidine-containing compound transmembrane transport 1/719 14/18722 0.422153321932222 0.876167271934801 SLC29A1 1 GO:0086103 G protein-coupled receptor signaling pathway involved in heart process 1/719 14/18722 0.422153321932222 0.876167271934801 CAV1 1 GO:0090128 regulation of synapse maturation 1/719 14/18722 0.422153321932222 0.876167271934801 CDC20 1 GO:0090239 regulation of histone H4 acetylation 1/719 14/18722 0.422153321932222 0.876167271934801 PIH1D1 1 GO:0090281 negative regulation of calcium ion import 1/719 14/18722 0.422153321932222 0.876167271934801 VDAC1 1 GO:0090308 regulation of DNA methylation-dependent heterochromatin assembly 1/719 14/18722 0.422153321932222 0.876167271934801 DNMT1 1 GO:0099188 postsynaptic cytoskeleton organization 1/719 14/18722 0.422153321932222 0.876167271934801 ACTG1 1 GO:0099638 endosome to plasma membrane protein transport 1/719 14/18722 0.422153321932222 0.876167271934801 NSG1 1 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading 1/719 14/18722 0.422153321932222 0.876167271934801 ITGB1BP1 1 GO:1903894 regulation of IRE1-mediated unfolded protein response 1/719 14/18722 0.422153321932222 0.876167271934801 BAX 1 GO:1904294 positive regulation of ERAD pathway 1/719 14/18722 0.422153321932222 0.876167271934801 CAV1 1 GO:2001171 positive regulation of ATP biosynthetic process 1/719 14/18722 0.422153321932222 0.876167271934801 ENO1 1 GO:0006805 xenobiotic metabolic process 5/719 111/18722 0.423486733478437 0.878030899135615 GSTO1/GSTP1/NUDT15/VKORC1/CYB5B 5 GO:0036294 cellular response to decreased oxygen levels 7/719 161/18722 0.423733042308138 0.878030899135615 ENO1/CHCHD2/CCNA2/CCNB1/PHB2/SLC29A1/BNIP3 7 GO:0043401 steroid hormone mediated signaling pathway 6/719 136/18722 0.423963491296911 0.878030899135615 YWHAH/PTGES3/PARK7/PHB/PARP1/PHB2 6 GO:0043624 cellular protein complex disassembly 6/719 136/18722 0.423963491296911 0.878030899135615 STMN1/TPX2/CFL1/DSTN/CKAP2/EIF5A 6 GO:0010466 negative regulation of peptidase activity 11/719 262/18722 0.424854419902561 0.879402965927344 PTTG1/GAPDH/BIRC5/PEBP1/PARK7/ANXA2/PRDX5/BCL2L12/PRDX3/TRIAP1/PIH1D1 11 GO:0051090 regulation of DNA-binding transcription factor activity 18/719 440/18722 0.425758303043382 0.8808003582574 PPIA/PRDX2/NPM1/RPS3/PARK7/ANXA3/UBE2N/PRDX3/EZH2/CAV1/CDKN2A/MDFI/PHB2/SUMO1/TFDP1/ID1/ID3/BUD31 18 GO:0002260 lymphocyte homeostasis 3/719 62/18722 0.427428745964257 0.881414393123937 RPS6/CCNB2/BAX 3 GO:0032615 interleukin-12 production 3/719 62/18722 0.427428745964257 0.881414393123937 HMGB1/HSPD1/C1QBP 3 GO:0032623 interleukin-2 production 3/719 62/18722 0.427428745964257 0.881414393123937 RPS3/STOML2/PNP 3 GO:0032655 regulation of interleukin-12 production 3/719 62/18722 0.427428745964257 0.881414393123937 HMGB1/HSPD1/C1QBP 3 GO:0032663 regulation of interleukin-2 production 3/719 62/18722 0.427428745964257 0.881414393123937 RPS3/STOML2/PNP 3 GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 3/719 62/18722 0.427428745964257 0.881414393123937 YWHAE/NSG1/HRAS 3 GO:0030258 lipid modification 9/719 212/18722 0.42767251705899 0.881444962889246 ACAT2/ECHS1/ETFB/ECH1/ECI1/ADH5/HADH/ETFA/HSD17B10 9 GO:0045936 negative regulation of phosphate metabolic process 18/719 441/18722 0.42957312130563 0.881661994385831 CALM2/PPIA/GSTP1/PBK/NPM1/CALM1/CCNB1/DYNLL1/PARK7/YWHAE/PRDX3/PKIB/CAV1/CDKN2A/PARP1/ITGB1BP1/ENSA/BAX 18 GO:0001776 leukocyte homeostasis 4/719 87/18722 0.430350853706115 0.881661994385831 HMGB1/RPS6/CCNB2/BAX 4 GO:0061014 positive regulation of mRNA catabolic process 4/719 87/18722 0.430350853706115 0.881661994385831 HNRNPD/EXOSC8/POLR2G/HNRNPR 4 GO:0006986 response to unfolded protein 6/719 137/18722 0.430820823902328 0.881661994385831 HSPE1/HSP90AB1/HSPD1/HSP90AA1/CCND1/BAX 6 GO:1901222 regulation of NIK/NF-kappaB signaling 5/719 112/18722 0.431086542066364 0.881661994385831 HMGB1/RPS3/PRDX1/PHB/PHB2 5 GO:0001825 blastocyst formation 2/719 38/18722 0.43167087257592 0.881661994385831 SF3B6/ACTL6A 2 GO:0008210 estrogen metabolic process 2/719 38/18722 0.43167087257592 0.881661994385831 COMT/HSD17B10 2 GO:0010613 positive regulation of cardiac muscle hypertrophy 2/719 38/18722 0.43167087257592 0.881661994385831 PARP1/PIN1 2 GO:0032373 positive regulation of sterol transport 2/719 38/18722 0.43167087257592 0.881661994385831 ANXA2/CAV1 2 GO:0032376 positive regulation of cholesterol transport 2/719 38/18722 0.43167087257592 0.881661994385831 ANXA2/CAV1 2 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway 2/719 38/18722 0.43167087257592 0.881661994385831 PHB/PHB2 2 GO:0035337 fatty-acyl-CoA metabolic process 2/719 38/18722 0.43167087257592 0.881661994385831 NUDT8/SLC25A1 2 GO:0046676 negative regulation of insulin secretion 2/719 38/18722 0.43167087257592 0.881661994385831 ENY2/HADH 2 GO:0048246 macrophage chemotaxis 2/719 38/18722 0.43167087257592 0.881661994385831 MIF/DDT 2 GO:0071392 cellular response to estradiol stimulus 2/719 38/18722 0.43167087257592 0.881661994385831 CCNA2/HNRNPD 2 GO:0098926 postsynaptic signal transduction 2/719 38/18722 0.43167087257592 0.881661994385831 LY6E/KPNA2 2 GO:1903725 regulation of phospholipid metabolic process 2/719 38/18722 0.43167087257592 0.881661994385831 STOML2/PHB2 2 GO:0051651 maintenance of location in cell 9/719 213/18722 0.433161825362586 0.882814685410023 CALM2/GSTO1/TXN/CALM1/PARK7/ARL2/CAV1/SKP1/BAX 9 GO:0010563 negative regulation of phosphorus metabolic process 18/719 442/18722 0.433388744744852 0.882814685410023 CALM2/PPIA/GSTP1/PBK/NPM1/CALM1/CCNB1/DYNLL1/PARK7/YWHAE/PRDX3/PKIB/CAV1/CDKN2A/PARP1/ITGB1BP1/ENSA/BAX 18 GO:0018105 peptidyl-serine phosphorylation 13/719 315/18722 0.435418607225163 0.882814685410023 CDK1/AURKB/TXN/MIF/CLSPN/CCNB1/PARK7/AURKA/VRK1/HSP90AB1/HSP90AA1/CAV1/BAX 13 GO:0071322 cellular response to carbohydrate stimulus 7/719 163/18722 0.436317692220587 0.882814685410023 PHPT1/DYNLL1/NME1/MPC2/ENY2/PIH1D1/SLC29A1 7 GO:0016239 positive regulation of macroautophagy 3/719 63/18722 0.437665785251851 0.882814685410023 SLC25A5/VDAC1/BNIP3 3 GO:0050779 RNA destabilization 4/719 88/18722 0.438965865976132 0.882814685410023 HNRNPD/EXOSC8/POLR2G/HNRNPR 4 GO:0050829 defense response to Gram-negative bacterium 4/719 88/18722 0.438965865976132 0.882814685410023 HMGB2/RPS19/RPL30/ROMO1 4 GO:0002836 positive regulation of response to tumor cell 1/719 15/18722 0.444361562339039 0.882814685410023 HSPD1 1 GO:0002839 positive regulation of immune response to tumor cell 1/719 15/18722 0.444361562339039 0.882814685410023 HSPD1 1 GO:0006570 tyrosine metabolic process 1/719 15/18722 0.444361562339039 0.882814685410023 PCBD1 1 GO:0006825 copper ion transport 1/719 15/18722 0.444361562339039 0.882814685410023 COX17 1 GO:0006878 cellular copper ion homeostasis 1/719 15/18722 0.444361562339039 0.882814685410023 MT2A 1 GO:0007000 nucleolus organization 1/719 15/18722 0.444361562339039 0.882814685410023 RPS19 1 GO:0010940 positive regulation of necrotic cell death 1/719 15/18722 0.444361562339039 0.882814685410023 BNIP3 1 GO:0016114 terpenoid biosynthetic process 1/719 15/18722 0.444361562339039 0.882814685410023 FDPS 1 GO:0016446 somatic hypermutation of immunoglobulin genes 1/719 15/18722 0.444361562339039 0.882814685410023 UNG 1 GO:0018216 peptidyl-arginine methylation 1/719 15/18722 0.444361562339039 0.882814685410023 PRMT1 1 GO:0018410 C-terminal protein amino acid modification 1/719 15/18722 0.444361562339039 0.882814685410023 LCMT1 1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway 1/719 15/18722 0.444361562339039 0.882814685410023 PHB2 1 GO:0033275 actin-myosin filament sliding 1/719 15/18722 0.444361562339039 0.882814685410023 MYL6 1 GO:0035435 phosphate ion transmembrane transport 1/719 15/18722 0.444361562339039 0.882814685410023 SLC25A3 1 GO:0035493 SNARE complex assembly 1/719 15/18722 0.444361562339039 0.882814685410023 VAMP8 1 GO:0036124 histone H3-K9 trimethylation 1/719 15/18722 0.444361562339039 0.882814685410023 PIH1D1 1 GO:0042994 cytoplasmic sequestering of transcription factor 1/719 15/18722 0.444361562339039 0.882814685410023 MDFI 1 GO:0043508 negative regulation of JUN kinase activity 1/719 15/18722 0.444361562339039 0.882814685410023 GSTP1 1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 1/719 15/18722 0.444361562339039 0.882814685410023 MIF 1 GO:0044406 adhesion of symbiont to host 1/719 15/18722 0.444361562339039 0.882814685410023 HSP90AB1 1 GO:0045836 positive regulation of meiotic nuclear division 1/719 15/18722 0.444361562339039 0.882814685410023 RAD51AP1 1 GO:0045986 negative regulation of smooth muscle contraction 1/719 15/18722 0.444361562339039 0.882814685410023 SOD1 1 GO:0046184 aldehyde biosynthetic process 1/719 15/18722 0.444361562339039 0.882814685410023 TPI1 1 GO:0050746 regulation of lipoprotein metabolic process 1/719 15/18722 0.444361562339039 0.882814685410023 DBI 1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound 1/719 15/18722 0.444361562339039 0.882814685410023 MKKS 1 GO:0051608 histamine transport 1/719 15/18722 0.444361562339039 0.882814685410023 VAMP8 1 GO:0051775 response to redox state 1/719 15/18722 0.444361562339039 0.882814685410023 ADH5 1 GO:0060026 convergent extension 1/719 15/18722 0.444361562339039 0.882814685410023 MKKS 1 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 1/719 15/18722 0.444361562339039 0.882814685410023 POLR2G 1 GO:0060253 negative regulation of glial cell proliferation 1/719 15/18722 0.444361562339039 0.882814685410023 IDH2 1 GO:0060766 negative regulation of androgen receptor signaling pathway 1/719 15/18722 0.444361562339039 0.882814685410023 PHB 1 GO:0070207 protein homotrimerization 1/719 15/18722 0.444361562339039 0.882814685410023 MIF 1 GO:0071025 RNA surveillance 1/719 15/18722 0.444361562339039 0.882814685410023 EXOSC8 1 GO:0072044 collecting duct development 1/719 15/18722 0.444361562339039 0.882814685410023 AKR1B1 1 GO:0097468 programmed cell death in response to reactive oxygen species 1/719 15/18722 0.444361562339039 0.882814685410023 PARK7 1 GO:1901841 regulation of high voltage-gated calcium channel activity 1/719 15/18722 0.444361562339039 0.882814685410023 CALM1 1 GO:1903727 positive regulation of phospholipid metabolic process 1/719 15/18722 0.444361562339039 0.882814685410023 STOML2 1 GO:1904424 regulation of GTP binding 1/719 15/18722 0.444361562339039 0.882814685410023 STMN1 1 GO:1905288 vascular associated smooth muscle cell apoptotic process 1/719 15/18722 0.444361562339039 0.882814685410023 DNMT1 1 GO:1905459 regulation of vascular associated smooth muscle cell apoptotic process 1/719 15/18722 0.444361562339039 0.882814685410023 DNMT1 1 GO:2000104 negative regulation of DNA-dependent DNA replication 1/719 15/18722 0.444361562339039 0.882814685410023 GMNN 1 GO:0016579 protein deubiquitination 6/719 139/18722 0.444493743355005 0.882814685410023 CDK1/PARK7/EIF3F/ENY2/PSMD14/USP1 6 GO:0014742 positive regulation of muscle hypertrophy 2/719 39/18722 0.444846880440375 0.882814685410023 PARP1/PIN1 2 GO:0032506 cytokinetic process 2/719 39/18722 0.444846880440375 0.882814685410023 AURKB/ECT2 2 GO:0043267 negative regulation of potassium ion transport 2/719 39/18722 0.444846880440375 0.882814685410023 CAV1/SUMO1 2 GO:0051154 negative regulation of striated muscle cell differentiation 2/719 39/18722 0.444846880440375 0.882814685410023 YBX1/EZH2 2 GO:0086091 regulation of heart rate by cardiac conduction 2/719 39/18722 0.444846880440375 0.882814685410023 YWHAE/CAV1 2 GO:2000249 regulation of actin cytoskeleton reorganization 2/719 39/18722 0.444846880440375 0.882814685410023 PHPT1/HRAS 2 GO:0051261 protein depolymerization 5/719 114/18722 0.446221016269117 0.885085477916589 STMN1/TPX2/CFL1/DSTN/CKAP2 5 GO:0045995 regulation of embryonic development 3/719 64/18722 0.44783276074915 0.887824989126791 CDK1/CFL1/PHLDA2 3 GO:0050796 regulation of insulin secretion 7/719 165/18722 0.44886177946356 0.889407025699798 PHPT1/DYNLL1/MPC2/UQCC2/ENY2/HADH/ENSA 7 GO:0015748 organophosphate ester transport 6/719 140/18722 0.451305643484688 0.893789468835416 SLC25A5/SLC25A6/DBI/PRELID1/TRIAP1/SLC29A1 6 GO:1901214 regulation of neuron death 13/719 319/18722 0.45346503198152 0.894270358367069 SOD1/PARK7/UBB/HSP90AB1/HSPD1/SET/PSMC1/NENF/PARP1/PIN1/NAE1/HRAS/BAX 13 GO:0034968 histone lysine methylation 5/719 115/18722 0.453750878554674 0.894270358367069 TRMT112/EZH2/PIH1D1/DPY30/DNMT1 5 GO:0043279 response to alkaloid 5/719 115/18722 0.453750878554674 0.894270358367069 RAD51/CCNA2/HSP90AB1/HSPD1/SRSF9 5 GO:0032970 regulation of actin filament-based process 16/719 396/18722 0.453800237441913 0.894270358367069 STMN1/S100A10/PFN1/PHPT1/ACTG1/DSTN/ARPC1A/CAV1/ARPC5/ECT2/RHOC/ARPC5L/MKKS/HRAS/ID1/ITGB1BP1 16 GO:0007596 blood coagulation 9/719 217/18722 0.455063362891312 0.894270358367069 PPIA/PRDX2/ANXA5/ACTG1/ANXA2/GNAS/CAV1/VKORC1/FIBP 9 GO:0006400 tRNA modification 4/719 90/18722 0.456078140702856 0.894270358367069 TRMT112/TPRKB/SSB/HSD17B10 4 GO:0034109 homotypic cell-cell adhesion 4/719 90/18722 0.456078140702856 0.894270358367069 PPIA/ACTG1/GNAS/FIBP 4 GO:0006730 one-carbon metabolic process 2/719 40/18722 0.457850661156336 0.894270358367069 TYMS/DHFR 2 GO:0009069 serine family amino acid metabolic process 2/719 40/18722 0.457850661156336 0.894270358367069 GCSH/DHFR 2 GO:0014037 Schwann cell differentiation 2/719 40/18722 0.457850661156336 0.894270358367069 CDK1/SOD1 2 GO:0032094 response to food 2/719 40/18722 0.457850661156336 0.894270358367069 NENF/MKKS 2 GO:0042073 intraciliary transport 2/719 40/18722 0.457850661156336 0.894270358367069 HSPB11/SSNA1 2 GO:0045429 positive regulation of nitric oxide biosynthetic process 2/719 40/18722 0.457850661156336 0.894270358367069 HSP90AB1/HSP90AA1 2 GO:0046365 monosaccharide catabolic process 2/719 40/18722 0.457850661156336 0.894270358367069 ENO1/NUDT5 2 GO:0070266 necroptotic process 2/719 40/18722 0.457850661156336 0.894270358367069 CAV1/PPIF 2 GO:0097352 autophagosome maturation 2/719 40/18722 0.457850661156336 0.894270358367069 CALM1/VAMP8 2 GO:2000781 positive regulation of double-strand break repair 2/719 40/18722 0.457850661156336 0.894270358367069 RAD51AP1/PARP1 2 GO:0033692 cellular polysaccharide biosynthetic process 3/719 65/18722 0.457924960203369 0.894270358367069 PTGES3/PPP1CA/UGP2 3 GO:0035418 protein localization to synapse 3/719 65/18722 0.457924960203369 0.894270358367069 NSG1/HRAS/ZDHHC12 3 GO:0038034 signal transduction in absence of ligand 3/719 65/18722 0.457924960203369 0.894270358367069 PRDX2/PPP1CA/BAX 3 GO:0070613 regulation of protein processing 3/719 65/18722 0.457924960203369 0.894270358367069 ENO1/BCL2L12/BAG2 3 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 3/719 65/18722 0.457924960203369 0.894270358367069 PRDX2/PPP1CA/BAX 3 GO:0048284 organelle fusion 6/719 141/18722 0.458098779844616 0.894270358367069 CDK1/ANXA2/STOML2/VAMP8/BNIP3/BAX 6 GO:0032872 regulation of stress-activated MAPK cascade 8/719 192/18722 0.458101107785528 0.894270358367069 HMGB1/PPIA/GSTP1/PBK/PAGE4/PRDX1/PRMT1/HRAS 8 GO:0018107 peptidyl-threonine phosphorylation 5/719 116/18722 0.461252734136332 0.894270358367069 CDK1/CALM2/CALM1/VRK1/CSNK2B 5 GO:0033559 unsaturated fatty acid metabolic process 5/719 116/18722 0.461252734136332 0.894270358367069 GSTP1/MIF/PTGES3/GPX4/AKR1B1 5 GO:0002275 myeloid cell activation involved in immune response 4/719 91/18722 0.46456905981731 0.894270358367069 HMGB1/ANXA3/S100A13/VAMP8 4 GO:0060191 regulation of lipase activity 4/719 91/18722 0.46456905981731 0.894270358367069 RHOC/PHB/PHB2/HRAS 4 GO:0002093 auditory receptor cell morphogenesis 1/719 16/18722 0.465717420396357 0.894270358367069 SOD1 1 GO:0002566 somatic diversification of immune receptors via somatic mutation 1/719 16/18722 0.465717420396357 0.894270358367069 UNG 1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 1/719 16/18722 0.465717420396357 0.894270358367069 RPL26 1 GO:0010225 response to UV-C 1/719 16/18722 0.465717420396357 0.894270358367069 HMGN1 1 GO:0016074 sno(s)RNA metabolic process 1/719 16/18722 0.465717420396357 0.894270358367069 FBL 1 GO:0030540 female genitalia development 1/719 16/18722 0.465717420396357 0.894270358367069 BAX 1 GO:0030575 nuclear body organization 1/719 16/18722 0.465717420396357 0.894270358367069 SERBP1 1 GO:0031268 pseudopodium organization 1/719 16/18722 0.465717420396357 0.894270358367069 RAB25 1 GO:0034138 toll-like receptor 3 signaling pathway 1/719 16/18722 0.465717420396357 0.894270358367069 CAV1 1 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter 1/719 16/18722 0.465717420396357 0.894270358367069 EZH2 1 GO:0034393 positive regulation of smooth muscle cell apoptotic process 1/719 16/18722 0.465717420396357 0.894270358367069 CDKN2A 1 GO:0035864 response to potassium ion 1/719 16/18722 0.465717420396357 0.894270358367069 SOD1 1 GO:0043923 positive regulation by host of viral transcription 1/719 16/18722 0.465717420396357 0.894270358367069 NUCKS1 1 GO:0044849 estrous cycle 1/719 16/18722 0.465717420396357 0.894270358367069 PCNA 1 GO:0045721 negative regulation of gluconeogenesis 1/719 16/18722 0.465717420396357 0.894270358367069 PGP 1 GO:0045838 positive regulation of membrane potential 1/719 16/18722 0.465717420396357 0.894270358367069 STOML2 1 GO:0048385 regulation of retinoic acid receptor signaling pathway 1/719 16/18722 0.465717420396357 0.894270358367069 EZH2 1 GO:0050862 positive regulation of T cell receptor signaling pathway 1/719 16/18722 0.465717420396357 0.894270358367069 RPS3 1 GO:0050884 neuromuscular process controlling posture 1/719 16/18722 0.465717420396357 0.894270358367069 PNKD 1 GO:0060330 regulation of response to interferon-gamma 1/719 16/18722 0.465717420396357 0.894270358367069 HSP90AB1 1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway 1/719 16/18722 0.465717420396357 0.894270358367069 HSP90AB1 1 GO:0070242 thymocyte apoptotic process 1/719 16/18722 0.465717420396357 0.894270358367069 BAX 1 GO:0070365 hepatocyte differentiation 1/719 16/18722 0.465717420396357 0.894270358367069 KRT18 1 GO:0071639 positive regulation of monocyte chemotactic protein-1 production 1/719 16/18722 0.465717420396357 0.894270358367069 HMGB1 1 GO:0098969 neurotransmitter receptor transport to postsynaptic membrane 1/719 16/18722 0.465717420396357 0.894270358367069 NSG1 1 GO:0099010 modification of postsynaptic structure 1/719 16/18722 0.465717420396357 0.894270358367069 PFN1 1 GO:0099633 protein localization to postsynaptic specialization membrane 1/719 16/18722 0.465717420396357 0.894270358367069 HRAS 1 GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane 1/719 16/18722 0.465717420396357 0.894270358367069 HRAS 1 GO:1901163 regulation of trophoblast cell migration 1/719 16/18722 0.465717420396357 0.894270358367069 C1QBP 1 GO:1902931 negative regulation of alcohol biosynthetic process 1/719 16/18722 0.465717420396357 0.894270358367069 SOD1 1 GO:2000232 regulation of rRNA processing 1/719 16/18722 0.465717420396357 0.894270358367069 TRMT112 1 GO:2000765 regulation of cytoplasmic translation 1/719 16/18722 0.465717420396357 0.894270358367069 PKM 1 GO:2001044 regulation of integrin-mediated signaling pathway 1/719 16/18722 0.465717420396357 0.894270358367069 ITGB1BP1 1 GO:0030193 regulation of blood coagulation 3/719 66/18722 0.467937942927014 0.896193176620413 PRDX2/ANXA2/CAV1 3 GO:0050918 positive chemotaxis 3/719 66/18722 0.467937942927014 0.896193176620413 HMGB2/HMGB1/MIF 3 GO:0050922 negative regulation of chemotaxis 3/719 66/18722 0.467937942927014 0.896193176620413 GSTP1/MIF/DDT 3 GO:0051893 regulation of focal adhesion assembly 3/719 66/18722 0.467937942927014 0.896193176620413 S100A10/ACTG1/ITGB1BP1 3 GO:0090109 regulation of cell-substrate junction assembly 3/719 66/18722 0.467937942927014 0.896193176620413 S100A10/ACTG1/ITGB1BP1 3 GO:0001953 negative regulation of cell-matrix adhesion 2/719 41/18722 0.470676000812072 0.896193176620413 CDKN2A/ITGB1BP1 2 GO:0030488 tRNA methylation 2/719 41/18722 0.470676000812072 0.896193176620413 TRMT112/HSD17B10 2 GO:0032733 positive regulation of interleukin-10 production 2/719 41/18722 0.470676000812072 0.896193176620413 HMGB1/HSPD1 2 GO:0032735 positive regulation of interleukin-12 production 2/719 41/18722 0.470676000812072 0.896193176620413 HMGB1/HSPD1 2 GO:0050856 regulation of T cell receptor signaling pathway 2/719 41/18722 0.470676000812072 0.896193176620413 RPS3/PHPT1 2 GO:0060612 adipose tissue development 2/719 41/18722 0.470676000812072 0.896193176620413 UBB/CDK4 2 GO:0071470 cellular response to osmotic stress 2/719 41/18722 0.470676000812072 0.896193176620413 XRCC6/AKR1B1 2 GO:0071634 regulation of transforming growth factor beta production 2/719 41/18722 0.470676000812072 0.896193176620413 HSP90AB1/CD24 2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 2/719 41/18722 0.470676000812072 0.896193176620413 S100A10/C1QBP 2 GO:1900371 regulation of purine nucleotide biosynthetic process 2/719 41/18722 0.470676000812072 0.896193176620413 ENO1/PARP1 2 GO:1904407 positive regulation of nitric oxide metabolic process 2/719 41/18722 0.470676000812072 0.896193176620413 HSP90AB1/HSP90AA1 2 GO:1905521 regulation of macrophage migration 2/719 41/18722 0.470676000812072 0.896193176620413 MIF/DDT 2 GO:0038061 NIK/NF-kappaB signaling 6/719 143/18722 0.471621835355819 0.897550205694465 HMGB1/RPS3/PRDX1/PHB/PHB2/PPP4C 6 GO:0031058 positive regulation of histone modification 4/719 92/18722 0.473012478242469 0.899172063553627 CCNB1/UBE2N/PIH1D1/DNMT1 4 GO:0048525 negative regulation of viral process 4/719 92/18722 0.473012478242469 0.899172063553627 PPIA/LY6E/BANF1/SNX3 4 GO:0006937 regulation of muscle contraction 7/719 169/18722 0.473782480547654 0.899172063553627 CALM2/GSTO1/ENO1/CALM1/SOD1/CAV1/C12orf57 7 GO:0030073 insulin secretion 8/719 195/18722 0.475468742464105 0.899172063553627 PHPT1/DYNLL1/PARK7/MPC2/UQCC2/ENY2/HADH/ENSA 8 GO:0070302 regulation of stress-activated protein kinase signaling cascade 8/719 195/18722 0.475468742464105 0.899172063553627 HMGB1/PPIA/GSTP1/PBK/PAGE4/PRDX1/PRMT1/HRAS 8 GO:0006879 cellular iron ion homeostasis 3/719 67/18722 0.477867533326974 0.899172063553627 SOD1/GLRX3/ISCU 3 GO:0010517 regulation of phospholipase activity 3/719 67/18722 0.477867533326974 0.899172063553627 PHB/PHB2/HRAS 3 GO:0016445 somatic diversification of immunoglobulins 3/719 67/18722 0.477867533326974 0.899172063553627 UNG/CTNNBL1/HSPD1 3 GO:0061180 mammary gland epithelium development 3/719 67/18722 0.477867533326974 0.899172063553627 CCND1/PHB2/BAX 3 GO:1903317 regulation of protein maturation 3/719 67/18722 0.477867533326974 0.899172063553627 ENO1/BCL2L12/BAG2 3 GO:0031098 stress-activated protein kinase signaling cascade 10/719 247/18722 0.477953544921496 0.899172063553627 HMGB1/PPIA/GSTP1/PBK/PAGE4/PRDX1/DUSP9/AKR1B1/PRMT1/HRAS 10 GO:0106106 cold-induced thermogenesis 6/719 144/18722 0.478348395784524 0.899172063553627 GNAS/CAV1/HADH/RHEB/FH/ID1 6 GO:0120161 regulation of cold-induced thermogenesis 6/719 144/18722 0.478348395784524 0.899172063553627 GNAS/CAV1/HADH/RHEB/FH/ID1 6 GO:0007599 hemostasis 9/719 222/18722 0.482241870009967 0.899172063553627 PPIA/PRDX2/ANXA5/ACTG1/ANXA2/GNAS/CAV1/VKORC1/FIBP 9 GO:0050817 coagulation 9/719 222/18722 0.482241870009967 0.899172063553627 PPIA/PRDX2/ANXA5/ACTG1/ANXA2/GNAS/CAV1/VKORC1/FIBP 9 GO:0000266 mitochondrial fission 2/719 42/18722 0.483317415169708 0.899172063553627 AURKA/BNIP3 2 GO:0007212 dopamine receptor signaling pathway 2/719 42/18722 0.483317415169708 0.899172063553627 GNAS/NSG1 2 GO:0014912 negative regulation of smooth muscle cell migration 2/719 42/18722 0.483317415169708 0.899172063553627 GSTP1/APEX1 2 GO:0021879 forebrain neuron differentiation 2/719 42/18722 0.483317415169708 0.899172063553627 UQCRQ/UBB 2 GO:0030808 regulation of nucleotide biosynthetic process 2/719 42/18722 0.483317415169708 0.899172063553627 ENO1/PARP1 2 GO:0032689 negative regulation of interferon-gamma production 2/719 42/18722 0.483317415169708 0.899172063553627 HMGB1/C1QBP 2 GO:0045047 protein targeting to ER 2/719 42/18722 0.483317415169708 0.899172063553627 SRP14/SRP9 2 GO:0046596 regulation of viral entry into host cell 2/719 42/18722 0.483317415169708 0.899172063553627 LY6E/SNX3 2 GO:0071312 cellular response to alkaloid 2/719 42/18722 0.483317415169708 0.899172063553627 RAD51/CCNA2 2 GO:0010906 regulation of glucose metabolic process 5/719 119/18722 0.483568271587592 0.899172063553627 HMGB1/PPP1CA/PGP/PHLDA2/LCMT1 5 GO:0000097 sulfur amino acid biosynthetic process 1/719 17/18722 0.486253567874974 0.899172063553627 ADI1 1 GO:0001780 neutrophil homeostasis 1/719 17/18722 0.486253567874974 0.899172063553627 HMGB1 1 GO:0006474 N-terminal protein amino acid acetylation 1/719 17/18722 0.486253567874974 0.899172063553627 NAA10 1 GO:0006577 amino-acid betaine metabolic process 1/719 17/18722 0.486253567874974 0.899172063553627 ALDH7A1 1 GO:0007625 grooming behavior 1/719 17/18722 0.486253567874974 0.899172063553627 APRT 1 GO:0010224 response to UV-B 1/719 17/18722 0.486253567874974 0.899172063553627 HMGN1 1 GO:0016264 gap junction assembly 1/719 17/18722 0.486253567874974 0.899172063553627 CAV1 1 GO:0020027 hemoglobin metabolic process 1/719 17/18722 0.486253567874974 0.899172063553627 PRMT1 1 GO:0021756 striatum development 1/719 17/18722 0.486253567874974 0.899172063553627 MKKS 1 GO:0021924 cell proliferation in external granule layer 1/719 17/18722 0.486253567874974 0.899172063553627 PSMG1 1 GO:0021930 cerebellar granule cell precursor proliferation 1/719 17/18722 0.486253567874974 0.899172063553627 PSMG1 1 GO:0030903 notochord development 1/719 17/18722 0.486253567874974 0.899172063553627 ID3 1 GO:0031445 regulation of heterochromatin assembly 1/719 17/18722 0.486253567874974 0.899172063553627 DNMT1 1 GO:0035518 histone H2A monoubiquitination 1/719 17/18722 0.486253567874974 0.899172063553627 SKP1 1 GO:0036035 osteoclast development 1/719 17/18722 0.486253567874974 0.899172063553627 ANXA2 1 GO:0036166 phenotypic switching 1/719 17/18722 0.486253567874974 0.899172063553627 DNMT1 1 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 1/719 17/18722 0.486253567874974 0.899172063553627 CAV1 1 GO:0042772 DNA damage response, signal transduction resulting in transcription 1/719 17/18722 0.486253567874974 0.899172063553627 RPL26 1 GO:0043649 dicarboxylic acid catabolic process 1/719 17/18722 0.486253567874974 0.899172063553627 QPRT 1 GO:0045815 positive regulation of gene expression, epigenetic 1/719 17/18722 0.486253567874974 0.899172063553627 CDCA4 1 GO:0046855 inositol phosphate dephosphorylation 1/719 17/18722 0.486253567874974 0.899172063553627 IMPA2 1 GO:0060263 regulation of respiratory burst 1/719 17/18722 0.486253567874974 0.899172063553627 RPS19 1 GO:0061158 3'-UTR-mediated mRNA destabilization 1/719 17/18722 0.486253567874974 0.899172063553627 HNRNPD 1 GO:0061450 trophoblast cell migration 1/719 17/18722 0.486253567874974 0.899172063553627 C1QBP 1 GO:0070206 protein trimerization 1/719 17/18722 0.486253567874974 0.899172063553627 MIF 1 GO:0070875 positive regulation of glycogen metabolic process 1/719 17/18722 0.486253567874974 0.899172063553627 HMGB1 1 GO:0071371 cellular response to gonadotropin stimulus 1/719 17/18722 0.486253567874974 0.899172063553627 CCNA2 1 GO:0090083 regulation of inclusion body assembly 1/719 17/18722 0.486253567874974 0.899172063553627 PSMC5 1 GO:0090494 dopamine uptake 1/719 17/18722 0.486253567874974 0.899172063553627 PARK7 1 GO:0120261 regulation of heterochromatin organization 1/719 17/18722 0.486253567874974 0.899172063553627 DNMT1 1 GO:1901569 fatty acid derivative catabolic process 1/719 17/18722 0.486253567874974 0.899172063553627 NUDT8 1 GO:1903540 establishment of protein localization to postsynaptic membrane 1/719 17/18722 0.486253567874974 0.899172063553627 NSG1 1 GO:2000696 regulation of epithelial cell differentiation involved in kidney development 1/719 17/18722 0.486253567874974 0.899172063553627 CD24 1 GO:2000811 negative regulation of anoikis 1/719 17/18722 0.486253567874974 0.899172063553627 CAV1 1 GO:0007585 respiratory gaseous exchange by respiratory system 3/719 68/18722 0.487709814246823 0.899273364391891 COX5B/ADH5/NDUFA12 3 GO:0032922 circadian regulation of gene expression 3/719 68/18722 0.487709814246823 0.899273364391891 PPP1CA/ID1/ID3 3 GO:0042267 natural killer cell mediated cytotoxicity 3/719 68/18722 0.487709814246823 0.899273364391891 TUBB/TUBB4B/PRDX1 3 GO:0051148 negative regulation of muscle cell differentiation 3/719 68/18722 0.487709814246823 0.899273364391891 YBX1/EZH2/DNMT1 3 GO:1900046 regulation of hemostasis 3/719 68/18722 0.487709814246823 0.899273364391891 PRDX2/ANXA2/CAV1 3 GO:1901016 regulation of potassium ion transmembrane transporter activity 3/719 68/18722 0.487709814246823 0.899273364391891 YWHAE/CAV1/SUMO1 3 GO:0006066 alcohol metabolic process 14/719 353/18722 0.489641405738688 0.902162736913952 TPI1/SOD1/DHFR/PARK7/FDPS/AKR7A2/IDH2/PGP/IMPA2/AKR1B1/ADH5/ISYNA1/PCBD1/PTS 14 GO:1902414 protein localization to cell junction 4/719 94/18722 0.489745485753288 0.902162736913952 ACTG1/NSG1/HRAS/ZDHHC12 4 GO:0010675 regulation of cellular carbohydrate metabolic process 6/719 146/18722 0.491723501821437 0.905373257777394 HMGB1/PGAM1/PPP1CA/PGP/PHLDA2/LCMT1 6 GO:0007548 sex differentiation 11/719 276/18722 0.493495435566016 0.908201446906865 HMGB2/NASP/RRM1/SOD1/EIF2S2/UBB/NUDT1/MEA1/CCND1/MKKS/BAX 11 GO:0001504 neurotransmitter uptake 2/719 43/18722 0.495770102922962 0.909778310892948 PARK7/SLC29A1 2 GO:0002861 regulation of inflammatory response to antigenic stimulus 2/719 43/18722 0.495770102922962 0.909778310892948 PARK7/PSMB4 2 GO:0042088 T-helper 1 type immune response 2/719 43/18722 0.495770102922962 0.909778310892948 HMGB1/HRAS 2 GO:0071604 transforming growth factor beta production 2/719 43/18722 0.495770102922962 0.909778310892948 HSP90AB1/CD24 2 GO:0090278 negative regulation of peptide hormone secretion 2/719 43/18722 0.495770102922962 0.909778310892948 ENY2/HADH 2 GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 2/719 43/18722 0.495770102922962 0.909778310892948 PRDX2/PPP1CA 2 GO:0010611 regulation of cardiac muscle hypertrophy 3/719 69/18722 0.497461120156952 0.90990447911487 PARP1/PIN1/GLRX3 3 GO:0002532 production of molecular mediator involved in inflammatory response 4/719 95/18722 0.498029715112636 0.90990447911487 PRDX2/RPS19/EZH2/VAMP8 4 GO:0042752 regulation of circadian rhythm 5/719 121/18722 0.498266143197277 0.90990447911487 CDK1/TOP2A/HNRNPD/PPP1CA/EZH2 5 GO:0043244 regulation of protein-containing complex disassembly 5/719 121/18722 0.498266143197277 0.90990447911487 TPX2/DSTN/CKAP2/EIF5A/BNIP3 5 GO:0008037 cell recognition 9/719 225/18722 0.498398523758177 0.90990447911487 ALDOA/CCT5/CCT2/VDAC2/CCT8/CCT3/CCT7/CCT4/TCP1 9 GO:0090257 regulation of muscle system process 10/719 252/18722 0.503445688797651 0.90990447911487 CALM2/GSTO1/ENO1/CALM1/SOD1/CAV1/C12orf57/PARP1/PIN1/GLRX3 10 GO:0007584 response to nutrient 7/719 174/18722 0.504508605217935 0.90990447911487 TYMS/LDHA/GSTP1/HAT1/COX4I1/CCND1/ENSA 7 GO:0019730 antimicrobial humoral response 5/719 122/18722 0.505555452669522 0.90990447911487 GAPDH/HMGN2/RPS19/RPL30/ROMO1 5 GO:0051928 positive regulation of calcium ion transport 5/719 122/18722 0.505555452669522 0.90990447911487 CALM2/GSTO1/CALM1/CAV1/BAX 5 GO:0000712 resolution of meiotic recombination intermediates 1/719 18/18722 0.506001425918166 0.90990447911487 TOP2A 1 GO:0002283 neutrophil activation involved in immune response 1/719 18/18722 0.506001425918166 0.90990447911487 ANXA3 1 GO:0002643 regulation of tolerance induction 1/719 18/18722 0.506001425918166 0.90990447911487 HMGB1 1 GO:0006085 acetyl-CoA biosynthetic process 1/719 18/18722 0.506001425918166 0.90990447911487 MPC2 1 GO:0006103 2-oxoglutarate metabolic process 1/719 18/18722 0.506001425918166 0.90990447911487 IDH2 1 GO:0006415 translational termination 1/719 18/18722 0.506001425918166 0.90990447911487 EIF5A 1 GO:0010663 positive regulation of striated muscle cell apoptotic process 1/719 18/18722 0.506001425918166 0.90990447911487 BNIP3 1 GO:0010666 positive regulation of cardiac muscle cell apoptotic process 1/719 18/18722 0.506001425918166 0.90990447911487 BNIP3 1 GO:0015936 coenzyme A metabolic process 1/719 18/18722 0.506001425918166 0.90990447911487 NUDT8 1 GO:0019896 axonal transport of mitochondrion 1/719 18/18722 0.506001425918166 0.90990447911487 HSBP1 1 GO:0021534 cell proliferation in hindbrain 1/719 18/18722 0.506001425918166 0.90990447911487 PSMG1 1 GO:0032769 negative regulation of monooxygenase activity 1/719 18/18722 0.506001425918166 0.90990447911487 CAV1 1 GO:0032785 negative regulation of DNA-templated transcription, elongation 1/719 18/18722 0.506001425918166 0.90990447911487 EZH2 1 GO:0033189 response to vitamin A 1/719 18/18722 0.506001425918166 0.90990447911487 TYMS 1 GO:0034134 toll-like receptor 2 signaling pathway 1/719 18/18722 0.506001425918166 0.90990447911487 HMGB1 1 GO:0034162 toll-like receptor 9 signaling pathway 1/719 18/18722 0.506001425918166 0.90990447911487 HMGB1 1 GO:0043217 myelin maintenance 1/719 18/18722 0.506001425918166 0.90990447911487 SOD1 1 GO:0045653 negative regulation of megakaryocyte differentiation 1/719 18/18722 0.506001425918166 0.90990447911487 PRMT1 1 GO:0046838 phosphorylated carbohydrate dephosphorylation 1/719 18/18722 0.506001425918166 0.90990447911487 IMPA2 1 GO:0050665 hydrogen peroxide biosynthetic process 1/719 18/18722 0.506001425918166 0.90990447911487 SOD1 1 GO:0051895 negative regulation of focal adhesion assembly 1/719 18/18722 0.506001425918166 0.90990447911487 ITGB1BP1 1 GO:0055070 copper ion homeostasis 1/719 18/18722 0.506001425918166 0.90990447911487 MT2A 1 GO:0060391 positive regulation of SMAD protein signal transduction 1/719 18/18722 0.506001425918166 0.90990447911487 PARP1 1 GO:0060546 negative regulation of necroptotic process 1/719 18/18722 0.506001425918166 0.90990447911487 CAV1 1 GO:0071318 cellular response to ATP 1/719 18/18722 0.506001425918166 0.90990447911487 SOD1 1 GO:0071360 cellular response to exogenous dsRNA 1/719 18/18722 0.506001425918166 0.90990447911487 CAV1 1 GO:0090493 catecholamine uptake 1/719 18/18722 0.506001425918166 0.90990447911487 PARK7 1 GO:0097107 postsynaptic density assembly 1/719 18/18722 0.506001425918166 0.90990447911487 ZDHHC12 1 GO:0098877 neurotransmitter receptor transport to plasma membrane 1/719 18/18722 0.506001425918166 0.90990447911487 NSG1 1 GO:0150118 negative regulation of cell-substrate junction organization 1/719 18/18722 0.506001425918166 0.90990447911487 ITGB1BP1 1 GO:1900006 positive regulation of dendrite development 1/719 18/18722 0.506001425918166 0.90990447911487 EZH2 1 GO:1900242 regulation of synaptic vesicle endocytosis 1/719 18/18722 0.506001425918166 0.90990447911487 CALM1 1 GO:1902683 regulation of receptor localization to synapse 1/719 18/18722 0.506001425918166 0.90990447911487 HRAS 1 GO:2000641 regulation of early endosome to late endosome transport 1/719 18/18722 0.506001425918166 0.90990447911487 SNX3 1 GO:0042632 cholesterol homeostasis 4/719 96/18722 0.506255721801759 0.909936754872442 TMEM97/CD24/CAV1/RALY 4 GO:0002066 columnar/cuboidal epithelial cell development 2/719 44/18722 0.5080299014607 0.910575009601348 TYMS/RHEB 2 GO:0002792 negative regulation of peptide secretion 2/719 44/18722 0.5080299014607 0.910575009601348 ENY2/HADH 2 GO:0030521 androgen receptor signaling pathway 2/719 44/18722 0.5080299014607 0.910575009601348 PARK7/PHB 2 GO:0031295 T cell costimulation 2/719 44/18722 0.5080299014607 0.910575009601348 CD24/CAV1 2 GO:0042554 superoxide anion generation 2/719 44/18722 0.5080299014607 0.910575009601348 GSTP1/SOD1 2 GO:0062208 positive regulation of pattern recognition receptor signaling pathway 2/719 44/18722 0.5080299014607 0.910575009601348 HMGB1/CAV1 2 GO:0050954 sensory perception of mechanical stimulus 7/719 175/18722 0.510584622771505 0.914728151545042 BIRC5/SOD1/TIMM8B/ALDH7A1/TIMM13/TIMM10/MKKS 7 GO:0006690 icosanoid metabolic process 5/719 123/18722 0.512802556681235 0.917847439899003 GSTP1/MIF/PTGES3/GPX4/AKR1B1 5 GO:0050852 T cell receptor signaling pathway 5/719 123/18722 0.512802556681235 0.917847439899003 RPS3/PHPT1/UBE2N/STOML2/HRAS 5 GO:0014909 smooth muscle cell migration 4/719 97/18722 0.514421123938009 0.919447653375025 GSTP1/S100A11/ARPC5/APEX1 4 GO:0055092 sterol homeostasis 4/719 97/18722 0.514421123938009 0.919447653375025 TMEM97/CD24/CAV1/RALY 4 GO:0120162 positive regulation of cold-induced thermogenesis 4/719 97/18722 0.514421123938009 0.919447653375025 GNAS/CAV1/HADH/FH 4 GO:0042326 negative regulation of phosphorylation 15/719 385/18722 0.514651868317709 0.919447653375025 CALM2/PPIA/GSTP1/PBK/NPM1/CALM1/CCNB1/DYNLL1/PARK7/PRDX3/PKIB/CAV1/CDKN2A/ITGB1BP1/BAX 15 GO:0002228 natural killer cell mediated immunity 3/719 71/18722 0.516677361290972 0.922210403787781 TUBB/TUBB4B/PRDX1 3 GO:0150116 regulation of cell-substrate junction organization 3/719 71/18722 0.516677361290972 0.922210403787781 S100A10/ACTG1/ITGB1BP1 3 GO:0002920 regulation of humoral immune response 2/719 45/18722 0.520093245013242 0.923256252978586 C1QBP/PHB 2 GO:0003009 skeletal muscle contraction 2/719 45/18722 0.520093245013242 0.923256252978586 GSTO1/C12orf57 2 GO:0035305 negative regulation of dephosphorylation 2/719 45/18722 0.520093245013242 0.923256252978586 YWHAE/ENSA 2 GO:0035384 thioester biosynthetic process 2/719 45/18722 0.520093245013242 0.923256252978586 MPC2/SLC25A1 2 GO:0045933 positive regulation of muscle contraction 2/719 45/18722 0.520093245013242 0.923256252978586 GSTO1/ENO1 2 GO:0046189 phenol-containing compound biosynthetic process 2/719 45/18722 0.520093245013242 0.923256252978586 PARK7/DDT 2 GO:0048599 oocyte development 2/719 45/18722 0.520093245013242 0.923256252978586 CCNB1/AURKA 2 GO:0071616 acyl-CoA biosynthetic process 2/719 45/18722 0.520093245013242 0.923256252978586 MPC2/SLC25A1 2 GO:2000273 positive regulation of signaling receptor activity 2/719 45/18722 0.520093245013242 0.923256252978586 PARK7/BUD31 2 GO:0061337 cardiac conduction 4/719 98/18722 0.522523656092369 0.923256252978586 CALM2/CALM1/YWHAE/CAV1 4 GO:0000729 DNA double-strand break processing 1/719 19/18722 0.524991212849562 0.923256252978586 UBE2N 1 GO:0002281 macrophage activation involved in immune response 1/719 19/18722 0.524991212849562 0.923256252978586 HMGB1 1 GO:0006007 glucose catabolic process 1/719 19/18722 0.524991212849562 0.923256252978586 ENO1 1 GO:0006309 apoptotic DNA fragmentation 1/719 19/18722 0.524991212849562 0.923256252978586 BAX 1 GO:0010738 regulation of protein kinase A signaling 1/719 19/18722 0.524991212849562 0.923256252978586 MIF 1 GO:0031290 retinal ganglion cell axon guidance 1/719 19/18722 0.524991212849562 0.923256252978586 RPL24 1 GO:0032026 response to magnesium ion 1/719 19/18722 0.524991212849562 0.923256252978586 CCND1 1 GO:0032695 negative regulation of interleukin-12 production 1/719 19/18722 0.524991212849562 0.923256252978586 C1QBP 1 GO:0036498 IRE1-mediated unfolded protein response 1/719 19/18722 0.524991212849562 0.923256252978586 BAX 1 GO:0042776 mitochondrial ATP synthesis coupled proton transport 1/719 19/18722 0.524991212849562 0.923256252978586 STOML2 1 GO:0044003 modulation by symbiont of host process 1/719 19/18722 0.524991212849562 0.923256252978586 PHB2 1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate 1/719 19/18722 0.524991212849562 0.923256252978586 TOP2A 1 GO:0045947 negative regulation of translational initiation 1/719 19/18722 0.524991212849562 0.923256252978586 RPL13A 1 GO:0051571 positive regulation of histone H3-K4 methylation 1/719 19/18722 0.524991212849562 0.923256252978586 DNMT1 1 GO:0062099 negative regulation of programmed necrotic cell death 1/719 19/18722 0.524991212849562 0.923256252978586 CAV1 1 GO:0070734 histone H3-K27 methylation 1/719 19/18722 0.524991212849562 0.923256252978586 EZH2 1 GO:0071545 inositol phosphate catabolic process 1/719 19/18722 0.524991212849562 0.923256252978586 IMPA2 1 GO:1901881 positive regulation of protein depolymerization 1/719 19/18722 0.524991212849562 0.923256252978586 DSTN 1 GO:1903204 negative regulation of oxidative stress-induced neuron death 1/719 19/18722 0.524991212849562 0.923256252978586 PARK7 1 GO:1903975 regulation of glial cell migration 1/719 19/18722 0.524991212849562 0.923256252978586 IDH2 1 GO:2000042 negative regulation of double-strand break repair via homologous recombination 1/719 19/18722 0.524991212849562 0.923256252978586 RMI2 1 GO:2000251 positive regulation of actin cytoskeleton reorganization 1/719 19/18722 0.524991212849562 0.923256252978586 HRAS 1 GO:0000271 polysaccharide biosynthetic process 3/719 72/18722 0.526136160788316 0.923256252978586 PTGES3/PPP1CA/UGP2 3 GO:0014743 regulation of muscle hypertrophy 3/719 72/18722 0.526136160788316 0.923256252978586 PARP1/PIN1/GLRX3 3 GO:0043903 regulation of biological process involved in symbiotic interaction 3/719 72/18722 0.526136160788316 0.923256252978586 LY6E/CAV1/SNX3 3 GO:0050709 negative regulation of protein secretion 3/719 72/18722 0.526136160788316 0.923256252978586 IDH2/ENY2/HADH 3 GO:0055021 regulation of cardiac muscle tissue growth 3/719 72/18722 0.526136160788316 0.923256252978586 CDK1/CCNB1/PIN1 3 GO:0071383 cellular response to steroid hormone stimulus 8/719 204/18722 0.526659219047204 0.923375015480503 GSTP1/YWHAH/PTGES3/PARK7/UBE2L3/PHB/PARP1/PHB2 8 GO:0051146 striated muscle cell differentiation 11/719 283/18722 0.527138686307735 0.923375015480503 CDK1/CSRP2/ACTG1/KRT19/CCNB1/YBX1/CACYBP/KRT8/MORF4L2/EZH2/PIN1 11 GO:0018210 peptidyl-threonine modification 5/719 125/18722 0.527163190656142 0.923375015480503 CDK1/CALM2/CALM1/VRK1/CSNK2B 5 GO:0051053 negative regulation of DNA metabolic process 5/719 125/18722 0.527163190656142 0.923375015480503 HNRNPA1/RPS3/RMI2/SUB1/PARP1 5 GO:0003300 cardiac muscle hypertrophy 4/719 99/18722 0.530561167587743 0.927638735337335 EZH2/PARP1/PIN1/GLRX3 4 GO:0021549 cerebellum development 4/719 99/18722 0.530561167587743 0.927638735337335 UQCRQ/HNRNPD/EZH2/ATIC 4 GO:0030838 positive regulation of actin filament polymerization 4/719 99/18722 0.530561167587743 0.927638735337335 PFN1/ARPC1A/ARPC5/ARPC5L 4 GO:0051153 regulation of striated muscle cell differentiation 4/719 99/18722 0.530561167587743 0.927638735337335 YBX1/MORF4L2/EZH2/PIN1 4 GO:0031056 regulation of histone modification 6/719 152/18722 0.531116827067733 0.92776759719182 CCNB1/PARK7/UBE2N/SET/PIH1D1/DNMT1 6 GO:0051092 positive regulation of NF-kappaB transcription factor activity 6/719 152/18722 0.531116827067733 0.92776759719182 PPIA/NPM1/RPS3/UBE2N/PRDX3/CAV1 6 GO:0031294 lymphocyte costimulation 2/719 46/18722 0.531957125064015 0.92797232963138 CD24/CAV1 2 GO:0031648 protein destabilization 2/719 46/18722 0.531957125064015 0.92797232963138 SERF2/RAD23A 2 GO:0072599 establishment of protein localization to endoplasmic reticulum 2/719 46/18722 0.531957125064015 0.92797232963138 SRP14/SRP9 2 GO:0042593 glucose homeostasis 10/719 258/18722 0.533565434914904 0.930356396930426 RPS6/PHPT1/DYNLL1/NME1/NUCKS1/PARK7/MPC2/ENY2/PIH1D1/SLC29A1 10 GO:0032456 endocytic recycling 3/719 73/18722 0.535491699611256 0.932264300098688 VPS29/SNX3/NSG1 3 GO:0043299 leukocyte degranulation 3/719 73/18722 0.535491699611256 0.932264300098688 ANXA3/S100A13/VAMP8 3 GO:0016311 dephosphorylation 16/719 417/18722 0.537778824408477 0.932264300098688 CALM2/PPIA/CDKN3/PHPT1/CALM1/HSP90AB1/YWHAE/PPP1CA/PGP/IMPA2/CSNK2B/PPM1G/ACP1/PIN1/PPP4C/ENSA 16 GO:0033500 carbohydrate homeostasis 10/719 259/18722 0.538525775614811 0.932264300098688 RPS6/PHPT1/DYNLL1/NME1/NUCKS1/PARK7/MPC2/ENY2/PIH1D1/SLC29A1 10 GO:0000963 mitochondrial RNA processing 1/719 20/18722 0.543251990155939 0.932264300098688 HSD17B10 1 GO:0003159 morphogenesis of an endothelium 1/719 20/18722 0.543251990155939 0.932264300098688 CSNK2B 1 GO:0006607 NLS-bearing protein import into nucleus 1/719 20/18722 0.543251990155939 0.932264300098688 KPNA2 1 GO:0006700 C21-steroid hormone biosynthetic process 1/719 20/18722 0.543251990155939 0.932264300098688 AKR1B1 1 GO:0009713 catechol-containing compound biosynthetic process 1/719 20/18722 0.543251990155939 0.932264300098688 PARK7 1 GO:0032211 negative regulation of telomere maintenance via telomerase 1/719 20/18722 0.543251990155939 0.932264300098688 HNRNPA1 1 GO:0033005 positive regulation of mast cell activation 1/719 20/18722 0.543251990155939 0.932264300098688 VAMP8 1 GO:0039535 regulation of RIG-I signaling pathway 1/719 20/18722 0.543251990155939 0.932264300098688 C1QBP 1 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate 1/719 20/18722 0.543251990155939 0.932264300098688 TOP2A 1 GO:0042423 catecholamine biosynthetic process 1/719 20/18722 0.543251990155939 0.932264300098688 PARK7 1 GO:0043651 linoleic acid metabolic process 1/719 20/18722 0.543251990155939 0.932264300098688 GSTP1 1 GO:0043984 histone H4-K16 acetylation 1/719 20/18722 0.543251990155939 0.932264300098688 PIH1D1 1 GO:0045063 T-helper 1 cell differentiation 1/719 20/18722 0.543251990155939 0.932264300098688 HMGB1 1 GO:0051900 regulation of mitochondrial depolarization 1/719 20/18722 0.543251990155939 0.932264300098688 PARP1 1 GO:0061154 endothelial tube morphogenesis 1/719 20/18722 0.543251990155939 0.932264300098688 CSNK2B 1 GO:0061318 renal filtration cell differentiation 1/719 20/18722 0.543251990155939 0.932264300098688 CD24 1 GO:0072112 glomerular visceral epithelial cell differentiation 1/719 20/18722 0.543251990155939 0.932264300098688 CD24 1 GO:0072567 chemokine (C-X-C motif) ligand 2 production 1/719 20/18722 0.543251990155939 0.932264300098688 HMGB1 1 GO:1901386 negative regulation of voltage-gated calcium channel activity 1/719 20/18722 0.543251990155939 0.932264300098688 CALM1 1 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/719 20/18722 0.543251990155939 0.932264300098688 PARK7 1 GO:1904263 positive regulation of TORC1 signaling 1/719 20/18722 0.543251990155939 0.932264300098688 PIH1D1 1 GO:1904292 regulation of ERAD pathway 1/719 20/18722 0.543251990155939 0.932264300098688 CAV1 1 GO:2000010 positive regulation of protein localization to cell surface 1/719 20/18722 0.543251990155939 0.932264300098688 HSP90AB1 1 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production 1/719 20/18722 0.543251990155939 0.932264300098688 HMGB1 1 GO:2000479 regulation of cAMP-dependent protein kinase activity 1/719 20/18722 0.543251990155939 0.932264300098688 PKIB 1 GO:0010761 fibroblast migration 2/719 47/18722 0.543619052914689 0.932264300098688 PDLIM1/ITGB1BP1 2 GO:0010799 regulation of peptidyl-threonine phosphorylation 2/719 47/18722 0.543619052914689 0.932264300098688 CALM2/CALM1 2 GO:0032008 positive regulation of TOR signaling 2/719 47/18722 0.543619052914689 0.932264300098688 PIH1D1/RHEB 2 GO:0042311 vasodilation 2/719 47/18722 0.543619052914689 0.932264300098688 SOD1/MKKS 2 GO:0045581 negative regulation of T cell differentiation 2/719 47/18722 0.543619052914689 0.932264300098688 HMGB1/PRDX2 2 GO:0045646 regulation of erythrocyte differentiation 2/719 47/18722 0.543619052914689 0.932264300098688 HMGB2/PRMT1 2 GO:0045911 positive regulation of DNA recombination 2/719 47/18722 0.543619052914689 0.932264300098688 RAD51AP1/PARP1 2 GO:0120163 negative regulation of cold-induced thermogenesis 2/719 47/18722 0.543619052914689 0.932264300098688 RHEB/ID1 2 GO:0120192 tight junction assembly 3/719 74/18722 0.544741464974923 0.933773214672063 ACTG1/ARL2/ECT2 3 GO:0042102 positive regulation of T cell proliferation 4/719 101/18722 0.546433088741185 0.936256071051875 HMGB1/RPS3/CD24/PNP 4 GO:0010970 transport along microtubule 6/719 155/18722 0.550333991290942 0.940624901135755 SOD1/UBB/HSBP1/HSPB11/UXT/SSNA1 6 GO:0046651 lymphocyte proliferation 11/719 288/18722 0.550728425713686 0.940624901135755 HMGB1/PRDX2/RPS3/RPS6/MIF/HELLS/CD24/IMPDH2/HSPD1/PNP/BAX 11 GO:0051260 protein homooligomerization 7/719 182/18722 0.552333351466076 0.940624901135755 TK1/ALDOA/MIF/SSBP1/ECT2/PRMT1/HSD17B10 7 GO:0006094 gluconeogenesis 3/719 75/18722 0.553883153274155 0.940624901135755 TPI1/PGP/SLC25A1 3 GO:1902369 negative regulation of RNA catabolic process 3/719 75/18722 0.553883153274155 0.940624901135755 YBX1/SLIRP/HNRNPD 3 GO:2001259 positive regulation of cation channel activity 3/719 75/18722 0.553883153274155 0.940624901135755 CALM2/GSTO1/CALM1 3 GO:0014897 striated muscle hypertrophy 4/719 102/18722 0.554263754123939 0.940624901135755 EZH2/PARP1/PIN1/GLRX3 4 GO:0034308 primary alcohol metabolic process 4/719 102/18722 0.554263754123939 0.940624901135755 PARK7/AKR7A2/AKR1B1/ADH5 4 GO:0002673 regulation of acute inflammatory response 2/719 48/18722 0.555077024297139 0.940624901135755 GSTP1/PARK7 2 GO:0002686 negative regulation of leukocyte migration 2/719 48/18722 0.555077024297139 0.940624901135755 MIF/DDT 2 GO:0043303 mast cell degranulation 2/719 48/18722 0.555077024297139 0.940624901135755 S100A13/VAMP8 2 GO:0061647 histone H3-K9 modification 2/719 48/18722 0.555077024297139 0.940624901135755 PIH1D1/DNMT1 2 GO:0120009 intermembrane lipid transfer 2/719 48/18722 0.555077024297139 0.940624901135755 PRELID1/TRIAP1 2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 2/719 48/18722 0.555077024297139 0.940624901135755 PPP1CA/CAV1 2 GO:0001933 negative regulation of protein phosphorylation 13/719 342/18722 0.55511200039058 0.940624901135755 CALM2/PPIA/GSTP1/PBK/NPM1/CALM1/CCNB1/PARK7/PKIB/CAV1/CDKN2A/ITGB1BP1/BAX 13 GO:0000002 mitochondrial genome maintenance 1/719 21/18722 0.560811706714482 0.940624901135755 PARP1 1 GO:0003091 renal water homeostasis 1/719 21/18722 0.560811706714482 0.940624901135755 AKR1B1 1 GO:0006067 ethanol metabolic process 1/719 21/18722 0.560811706714482 0.940624901135755 ADH5 1 GO:0006353 DNA-templated transcription, termination 1/719 21/18722 0.560811706714482 0.940624901135755 POLR3K 1 GO:0007289 spermatid nucleus differentiation 1/719 21/18722 0.560811706714482 0.940624901135755 HMGB2 1 GO:0008090 retrograde axonal transport 1/719 21/18722 0.560811706714482 0.940624901135755 SOD1 1 GO:0009067 aspartate family amino acid biosynthetic process 1/719 21/18722 0.560811706714482 0.940624901135755 ADI1 1 GO:0009070 serine family amino acid biosynthetic process 1/719 21/18722 0.560811706714482 0.940624901135755 DHFR 1 GO:0010988 regulation of low-density lipoprotein particle clearance 1/719 21/18722 0.560811706714482 0.940624901135755 ANXA2 1 GO:0016075 rRNA catabolic process 1/719 21/18722 0.560811706714482 0.940624901135755 EXOSC8 1 GO:0019985 translesion synthesis 1/719 21/18722 0.560811706714482 0.940624901135755 PCNA 1 GO:0023019 signal transduction involved in regulation of gene expression 1/719 21/18722 0.560811706714482 0.940624901135755 PARP1 1 GO:0035020 regulation of Rac protein signal transduction 1/719 21/18722 0.560811706714482 0.940624901135755 DYNLT1 1 GO:0035813 regulation of renal sodium excretion 1/719 21/18722 0.560811706714482 0.940624901135755 COMT 1 GO:0038083 peptidyl-tyrosine autophosphorylation 1/719 21/18722 0.560811706714482 0.940624901135755 CAV1 1 GO:0042454 ribonucleoside catabolic process 1/719 21/18722 0.560811706714482 0.940624901135755 PNP 1 GO:0046599 regulation of centriole replication 1/719 21/18722 0.560811706714482 0.940624901135755 NPM1 1 GO:0048714 positive regulation of oligodendrocyte differentiation 1/719 21/18722 0.560811706714482 0.940624901135755 RHEB 1 GO:0051767 nitric-oxide synthase biosynthetic process 1/719 21/18722 0.560811706714482 0.940624901135755 GSTP1 1 GO:0051769 regulation of nitric-oxide synthase biosynthetic process 1/719 21/18722 0.560811706714482 0.940624901135755 GSTP1 1 GO:0060117 auditory receptor cell development 1/719 21/18722 0.560811706714482 0.940624901135755 SOD1 1 GO:0060972 left/right pattern formation 1/719 21/18722 0.560811706714482 0.940624901135755 HSPB11 1 GO:0072311 glomerular epithelial cell differentiation 1/719 21/18722 0.560811706714482 0.940624901135755 CD24 1 GO:0090026 positive regulation of monocyte chemotaxis 1/719 21/18722 0.560811706714482 0.940624901135755 HMGB1 1 GO:0098698 postsynaptic specialization assembly 1/719 21/18722 0.560811706714482 0.940624901135755 ZDHHC12 1 GO:0150105 protein localization to cell-cell junction 1/719 21/18722 0.560811706714482 0.940624901135755 ACTG1 1 GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1/719 21/18722 0.560811706714482 0.940624901135755 SLC25A5 1 GO:1902259 regulation of delayed rectifier potassium channel activity 1/719 21/18722 0.560811706714482 0.940624901135755 SUMO1 1 GO:1902473 regulation of protein localization to synapse 1/719 21/18722 0.560811706714482 0.940624901135755 HRAS 1 GO:1903429 regulation of cell maturation 1/719 21/18722 0.560811706714482 0.940624901135755 AURKA 1 GO:2001014 regulation of skeletal muscle cell differentiation 1/719 21/18722 0.560811706714482 0.940624901135755 UQCC2 1 GO:0033673 negative regulation of kinase activity 9/719 237/18722 0.561393284778633 0.940624901135755 PPIA/GSTP1/NPM1/PARK7/PRDX3/PKIB/CAV1/CDKN2A/ITGB1BP1 9 GO:0002027 regulation of heart rate 4/719 103/18722 0.562021906265753 0.940624901135755 CALM2/CALM1/YWHAE/CAV1 4 GO:0032760 positive regulation of tumor necrosis factor production 4/719 103/18722 0.562021906265753 0.940624901135755 HMGB1/MIF/HSPD1/DDT 4 GO:0050773 regulation of dendrite development 4/719 103/18722 0.562021906265753 0.940624901135755 YWHAH/CDC20/EZH2/ID1 4 GO:0014823 response to activity 3/719 76/18722 0.562914662964293 0.940624901135755 CDK1/HSPD1/HADH 3 GO:0021536 diencephalon development 3/719 76/18722 0.562914662964293 0.940624901135755 UQCRQ/UBB/BAX 3 GO:0086001 cardiac muscle cell action potential 3/719 76/18722 0.562914662964293 0.940624901135755 CALM1/YWHAE/CAV1 3 GO:0140115 export across plasma membrane 3/719 76/18722 0.562914662964293 0.940624901135755 CALM2/CALM1/YWHAE 3 GO:0055001 muscle cell development 7/719 184/18722 0.563979124850813 0.940624901135755 CDK1/CSRP2/ACTG1/KRT19/CCNB1/KRT8/PIN1 7 GO:0032943 mononuclear cell proliferation 11/719 291/18722 0.564672069628223 0.940624901135755 HMGB1/PRDX2/RPS3/RPS6/MIF/HELLS/CD24/IMPDH2/HSPD1/PNP/BAX 11 GO:0043491 protein kinase B signaling 8/719 211/18722 0.565187097418228 0.940624901135755 TXN/PARK7/HSP90AB1/C1QBP/HSP90AA1/PHLDA3/PHB/ITGB1BP1 8 GO:0070661 leukocyte proliferation 12/719 318/18722 0.566299709573693 0.940624901135755 HMGB1/PRDX2/GSTP1/RPS3/RPS6/MIF/HELLS/CD24/IMPDH2/HSPD1/PNP/BAX 12 GO:0002204 somatic recombination of immunoglobulin genes involved in immune response 2/719 49/18722 0.566329485930567 0.940624901135755 UNG/HSPD1 2 GO:0002208 somatic diversification of immunoglobulins involved in immune response 2/719 49/18722 0.566329485930567 0.940624901135755 UNG/HSPD1 2 GO:0002279 mast cell activation involved in immune response 2/719 49/18722 0.566329485930567 0.940624901135755 S100A13/VAMP8 2 GO:0009409 response to cold 2/719 49/18722 0.566329485930567 0.940624901135755 HSPD1/HSP90AA1 2 GO:0009994 oocyte differentiation 2/719 49/18722 0.566329485930567 0.940624901135755 CCNB1/AURKA 2 GO:0021695 cerebellar cortex development 2/719 49/18722 0.566329485930567 0.940624901135755 UQCRQ/EZH2 2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 2/719 49/18722 0.566329485930567 0.940624901135755 RBX1/SKP1 2 GO:0045190 isotype switching 2/719 49/18722 0.566329485930567 0.940624901135755 UNG/HSPD1 2 GO:0046605 regulation of centrosome cycle 2/719 49/18722 0.566329485930567 0.940624901135755 NPM1/AURKA 2 GO:0051445 regulation of meiotic cell cycle 2/719 49/18722 0.566329485930567 0.940624901135755 RAD51AP1/CDC20 2 GO:0051932 synaptic transmission, GABAergic 2/719 49/18722 0.566329485930567 0.940624901135755 EZH2/ZDHHC12 2 GO:0072091 regulation of stem cell proliferation 2/719 49/18722 0.566329485930567 0.940624901135755 HMGB2/CCNE1 2 GO:0086009 membrane repolarization 2/719 49/18722 0.566329485930567 0.940624901135755 YWHAE/CAV1 2 GO:0018022 peptidyl-lysine methylation 5/719 131/18722 0.569063260680094 0.944029872294634 TRMT112/EZH2/PIH1D1/DPY30/DNMT1 5 GO:0045089 positive regulation of innate immune response 5/719 131/18722 0.569063260680094 0.944029872294634 HMGB2/HMGB1/RPS19/HSP90AA1/XRCC6 5 GO:0014896 muscle hypertrophy 4/719 104/18722 0.569705939491245 0.944029872294634 EZH2/PARP1/PIN1/GLRX3 4 GO:0060419 heart growth 4/719 104/18722 0.569705939491245 0.944029872294634 CDK1/CCNB1/DUSP9/PIN1 4 GO:0006469 negative regulation of protein kinase activity 8/719 212/18722 0.570579826059767 0.944029872294634 PPIA/GSTP1/NPM1/PARK7/PKIB/CAV1/CDKN2A/ITGB1BP1 8 GO:0051403 stress-activated MAPK cascade 9/719 239/18722 0.571579020632789 0.944029872294634 HMGB1/PPIA/GSTP1/PBK/PAGE4/PRDX1/DUSP9/PRMT1/HRAS 9 GO:0035966 response to topologically incorrect protein 6/719 159/18722 0.575386389907623 0.944029872294634 HSPE1/HSP90AB1/HSPD1/HSP90AA1/CCND1/BAX 6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 7/719 186/18722 0.575485716651022 0.944029872294634 GAPDH/EEF1D/UBE2N/UBE2I/S100A13/ECT2/RHOC 7 GO:0002448 mast cell mediated immunity 2/719 50/18722 0.577375303926917 0.944029872294634 S100A13/VAMP8 2 GO:0002639 positive regulation of immunoglobulin production 2/719 50/18722 0.577375303926917 0.944029872294634 PHB/PHB2 2 GO:0007140 male meiotic nuclear division 2/719 50/18722 0.577375303926917 0.944029872294634 UBB/RAD51C 2 GO:0019083 viral transcription 2/719 50/18722 0.577375303926917 0.944029872294634 NUCKS1/PSMC3 2 GO:2000677 regulation of transcription regulatory region DNA binding 2/719 50/18722 0.577375303926917 0.944029872294634 PARK7/PARP1 2 GO:0006359 regulation of transcription by RNA polymerase III 1/719 22/18722 0.57769724133147 0.944029872294634 PRDX5 1 GO:0006379 mRNA cleavage 1/719 22/18722 0.57769724133147 0.944029872294634 POLR2I 1 GO:0006907 pinocytosis 1/719 22/18722 0.57769724133147 0.944029872294634 CAV1 1 GO:0007398 ectoderm development 1/719 22/18722 0.57769724133147 0.944029872294634 TPT1 1 GO:0008211 glucocorticoid metabolic process 1/719 22/18722 0.57769724133147 0.944029872294634 YWHAH 1 GO:0010310 regulation of hydrogen peroxide metabolic process 1/719 22/18722 0.57769724133147 0.944029872294634 PRDX2 1 GO:0032402 melanosome transport 1/719 22/18722 0.57769724133147 0.944029872294634 MKKS 1 GO:0034629 cellular protein-containing complex localization 1/719 22/18722 0.57769724133147 0.944029872294634 MZT1 1 GO:0034755 iron ion transmembrane transport 1/719 22/18722 0.57769724133147 0.944029872294634 ISCU 1 GO:0035024 negative regulation of Rho protein signal transduction 1/719 22/18722 0.57769724133147 0.944029872294634 STMN1 1 GO:0035809 regulation of urine volume 1/719 22/18722 0.57769724133147 0.944029872294634 AKR1B1 1 GO:0036120 cellular response to platelet-derived growth factor stimulus 1/719 22/18722 0.57769724133147 0.944029872294634 CCNA2 1 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation 1/719 22/18722 0.57769724133147 0.944029872294634 HMGB1 1 GO:0045540 regulation of cholesterol biosynthetic process 1/719 22/18722 0.57769724133147 0.944029872294634 SOD1 1 GO:0046628 positive regulation of insulin receptor signaling pathway 1/719 22/18722 0.57769724133147 0.944029872294634 NUCKS1 1 GO:0048169 regulation of long-term neuronal synaptic plasticity 1/719 22/18722 0.57769724133147 0.944029872294634 HRAS 1 GO:0050860 negative regulation of T cell receptor signaling pathway 1/719 22/18722 0.57769724133147 0.944029872294634 PHPT1 1 GO:0051151 negative regulation of smooth muscle cell differentiation 1/719 22/18722 0.57769724133147 0.944029872294634 DNMT1 1 GO:0051220 cytoplasmic sequestering of protein 1/719 22/18722 0.57769724133147 0.944029872294634 MDFI 1 GO:0060444 branching involved in mammary gland duct morphogenesis 1/719 22/18722 0.57769724133147 0.944029872294634 PHB2 1 GO:0097164 ammonium ion metabolic process 1/719 22/18722 0.57769724133147 0.944029872294634 ALDH7A1 1 GO:0099563 modification of synaptic structure 1/719 22/18722 0.57769724133147 0.944029872294634 PFN1 1 GO:0106118 regulation of sterol biosynthetic process 1/719 22/18722 0.57769724133147 0.944029872294634 SOD1 1 GO:1900543 negative regulation of purine nucleotide metabolic process 1/719 22/18722 0.57769724133147 0.944029872294634 PARP1 1 GO:2000773 negative regulation of cellular senescence 1/719 22/18722 0.57769724133147 0.944029872294634 YBX1 1 GO:0032024 positive regulation of insulin secretion 3/719 78/18722 0.580639708207713 0.947230032457498 PHPT1/DYNLL1/MPC2 3 GO:0043297 apical junction assembly 3/719 78/18722 0.580639708207713 0.947230032457498 ARL2/ECT2/RHOC 3 GO:0043537 negative regulation of blood vessel endothelial cell migration 3/719 78/18722 0.580639708207713 0.947230032457498 HMGB1/CSNK2B/ITGB1BP1 3 GO:1901616 organic hydroxy compound catabolic process 3/719 78/18722 0.580639708207713 0.947230032457498 TPI1/COMT/IMPA2 3 GO:0072330 monocarboxylic acid biosynthetic process 8/719 214/18722 0.581274359931235 0.947863738134373 GSTP1/MIF/PTGES3/PARK7/GPX4/NDUFAB1/EIF6/HSD17B10 8 GO:0090263 positive regulation of canonical Wnt signaling pathway 4/719 106/18722 0.584845737889383 0.953166989611702 RPS12/CAV1/PIN1/RUVBL1 4 GO:0006636 unsaturated fatty acid biosynthetic process 2/719 51/18722 0.588213733952256 0.953166989611702 MIF/PTGES3 2 GO:0021872 forebrain generation of neurons 2/719 51/18722 0.588213733952256 0.953166989611702 UQCRQ/UBB 2 GO:0045104 intermediate filament cytoskeleton organization 2/719 51/18722 0.588213733952256 0.953166989611702 SOD1/KRT18 2 GO:0060043 regulation of cardiac muscle cell proliferation 2/719 51/18722 0.588213733952256 0.953166989611702 CDK1/CCNB1 2 GO:0060632 regulation of microtubule-based movement 2/719 51/18722 0.588213733952256 0.953166989611702 CFAP20/MKKS 2 GO:0001508 action potential 5/719 134/18722 0.589280336253126 0.953166989611702 CALM1/YWHAH/YWHAE/CAV1/SUMO1 5 GO:0010927 cellular component assembly involved in morphogenesis 4/719 107/18722 0.592298796379109 0.953166989611702 CSRP2/ACTG1/KRT19/KRT8 4 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 4/719 107/18722 0.592298796379109 0.953166989611702 HMGB1/MIF/HSPD1/DDT 4 GO:0051494 negative regulation of cytoskeleton organization 6/719 162/18722 0.593711533458095 0.953166989611702 STMN1/NPM1/PFN1/TPX2/CKAP2/MKKS 6 GO:0003323 type B pancreatic cell development 1/719 23/18722 0.593934443656746 0.953166989611702 RHEB 1 GO:0006929 substrate-dependent cell migration 1/719 23/18722 0.593934443656746 0.953166989611702 ITGB1BP1 1 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 1/719 23/18722 0.593934443656746 0.953166989611702 GSTP1 1 GO:0016578 histone deubiquitination 1/719 23/18722 0.593934443656746 0.953166989611702 ENY2 1 GO:0016973 poly(A)+ mRNA export from nucleus 1/719 23/18722 0.593934443656746 0.953166989611702 ENY2 1 GO:0018279 protein N-linked glycosylation via asparagine 1/719 23/18722 0.593934443656746 0.953166989611702 OST4 1 GO:0021544 subpallium development 1/719 23/18722 0.593934443656746 0.953166989611702 MKKS 1 GO:0030194 positive regulation of blood coagulation 1/719 23/18722 0.593934443656746 0.953166989611702 PRDX2 1 GO:0030325 adrenal gland development 1/719 23/18722 0.593934443656746 0.953166989611702 LY6E 1 GO:0031338 regulation of vesicle fusion 1/719 23/18722 0.593934443656746 0.953166989611702 ANXA2 1 GO:0032401 establishment of melanosome localization 1/719 23/18722 0.593934443656746 0.953166989611702 MKKS 1 GO:0032740 positive regulation of interleukin-17 production 1/719 23/18722 0.593934443656746 0.953166989611702 PHB 1 GO:0033081 regulation of T cell differentiation in thymus 1/719 23/18722 0.593934443656746 0.953166989611702 SOD1 1 GO:0035812 renal sodium excretion 1/719 23/18722 0.593934443656746 0.953166989611702 COMT 1 GO:0036119 response to platelet-derived growth factor 1/719 23/18722 0.593934443656746 0.953166989611702 CCNA2 1 GO:0040019 positive regulation of embryonic development 1/719 23/18722 0.593934443656746 0.953166989611702 CFL1 1 GO:0042438 melanin biosynthetic process 1/719 23/18722 0.593934443656746 0.953166989611702 DDT 1 GO:0045662 negative regulation of myoblast differentiation 1/719 23/18722 0.593934443656746 0.953166989611702 ID3 1 GO:0045932 negative regulation of muscle contraction 1/719 23/18722 0.593934443656746 0.953166989611702 SOD1 1 GO:0045980 negative regulation of nucleotide metabolic process 1/719 23/18722 0.593934443656746 0.953166989611702 PARP1 1 GO:0051446 positive regulation of meiotic cell cycle 1/719 23/18722 0.593934443656746 0.953166989611702 RAD51AP1 1 GO:0051882 mitochondrial depolarization 1/719 23/18722 0.593934443656746 0.953166989611702 PARP1 1 GO:0051904 pigment granule transport 1/719 23/18722 0.593934443656746 0.953166989611702 MKKS 1 GO:0060353 regulation of cell adhesion molecule production 1/719 23/18722 0.593934443656746 0.953166989611702 CAV1 1 GO:0060547 negative regulation of necrotic cell death 1/719 23/18722 0.593934443656746 0.953166989611702 CAV1 1 GO:0060575 intestinal epithelial cell differentiation 1/719 23/18722 0.593934443656746 0.953166989611702 TYMS 1 GO:0061050 regulation of cell growth involved in cardiac muscle cell development 1/719 23/18722 0.593934443656746 0.953166989611702 PIN1 1 GO:1900048 positive regulation of hemostasis 1/719 23/18722 0.593934443656746 0.953166989611702 PRDX2 1 GO:0008154 actin polymerization or depolymerization 8/719 217/18722 0.597078704453947 0.957783816838157 PFN1/CFL1/DSTN/DIAPH3/ARPC1A/ARPC5/ARPC5L/MKKS 8 GO:0009791 post-embryonic development 3/719 80/18722 0.597903561914653 0.957783816838157 HMGN1/C12orf57/BAX 3 GO:0120193 tight junction organization 3/719 80/18722 0.597903561914653 0.957783816838157 ACTG1/ARL2/ECT2 3 GO:1901264 carbohydrate derivative transport 3/719 80/18722 0.597903561914653 0.957783816838157 SLC25A5/SLC25A6/SLC29A1 3 GO:0009755 hormone-mediated signaling pathway 7/719 190/18722 0.598055141734787 0.957783816838157 YWHAH/PTGES3/PARK7/CSNK2B/PHB/PARP1/PHB2 7 GO:0045103 intermediate filament-based process 2/719 52/18722 0.598844393056131 0.958649028385075 SOD1/KRT18 2 GO:0022037 metencephalon development 4/719 108/18722 0.599672318004232 0.959263544310336 UQCRQ/HNRNPD/EZH2/ATIC 4 GO:0006633 fatty acid biosynthetic process 6/719 163/18722 0.599726584715579 0.959263544310336 GSTP1/MIF/PTGES3/GPX4/NDUFAB1/EIF6 6 GO:0007163 establishment or maintenance of cell polarity 8/719 218/18722 0.602280945264571 0.962181413740598 MAD2L1/PDLIM1/DYNLT1/HSP90AB1/HSP90AA1/ARPC5/RHOC/NSFL1C 8 GO:0030099 myeloid cell differentiation 14/719 381/18722 0.605643922954535 0.962181413740598 HMGB2/HMGB1/SLC25A5/RPS6/RPS19/RPS14/NME1/ANXA2/PRDX3/EIF6/GLO1/PRMT1/PARP1/PIR 14 GO:2000243 positive regulation of reproductive process 3/719 81/18722 0.606359235182122 0.962181413740598 RAD51AP1/AURKA/C1QBP 3 GO:0050671 positive regulation of lymphocyte proliferation 5/719 137/18722 0.608967119000235 0.962181413740598 HMGB1/RPS3/MIF/CD24/PNP 5 GO:0001541 ovarian follicle development 2/719 53/18722 0.609267233085094 0.962181413740598 SOD1/BAX 2 GO:0043113 receptor clustering 2/719 53/18722 0.609267233085094 0.962181413740598 SSNA1/ITGB1BP1 2 GO:0050819 negative regulation of coagulation 2/719 53/18722 0.609267233085094 0.962181413740598 ANXA5/ANXA2 2 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/719 24/18722 0.609548173535927 0.962181413740598 EXOSC8 1 GO:0002438 acute inflammatory response to antigenic stimulus 1/719 24/18722 0.609548173535927 0.962181413740598 PARK7 1 GO:0002755 MyD88-dependent toll-like receptor signaling pathway 1/719 24/18722 0.609548173535927 0.962181413740598 HSPD1 1 GO:0002922 positive regulation of humoral immune response 1/719 24/18722 0.609548173535927 0.962181413740598 PHB 1 GO:0006582 melanin metabolic process 1/719 24/18722 0.609548173535927 0.962181413740598 DDT 1 GO:0006817 phosphate ion transport 1/719 24/18722 0.609548173535927 0.962181413740598 SLC25A3 1 GO:0018196 peptidyl-asparagine modification 1/719 24/18722 0.609548173535927 0.962181413740598 OST4 1 GO:0018230 peptidyl-L-cysteine S-palmitoylation 1/719 24/18722 0.609548173535927 0.962181413740598 ZDHHC12 1 GO:0018231 peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine 1/719 24/18722 0.609548173535927 0.962181413740598 ZDHHC12 1 GO:0030810 positive regulation of nucleotide biosynthetic process 1/719 24/18722 0.609548173535927 0.962181413740598 ENO1 1 GO:0031639 plasminogen activation 1/719 24/18722 0.609548173535927 0.962181413740598 ENO1 1 GO:0035458 cellular response to interferon-beta 1/719 24/18722 0.609548173535927 0.962181413740598 NDUFA13 1 GO:0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 1/719 24/18722 0.609548173535927 0.962181413740598 C1QBP 1 GO:0043302 positive regulation of leukocyte degranulation 1/719 24/18722 0.609548173535927 0.962181413740598 VAMP8 1 GO:0044062 regulation of excretion 1/719 24/18722 0.609548173535927 0.962181413740598 COMT 1 GO:0050687 negative regulation of defense response to virus 1/719 24/18722 0.609548173535927 0.962181413740598 C1QBP 1 GO:0050820 positive regulation of coagulation 1/719 24/18722 0.609548173535927 0.962181413740598 PRDX2 1 GO:0051905 establishment of pigment granule localization 1/719 24/18722 0.609548173535927 0.962181413740598 MKKS 1 GO:0060561 apoptotic process involved in morphogenesis 1/719 24/18722 0.609548173535927 0.962181413740598 BAX 1 GO:0070841 inclusion body assembly 1/719 24/18722 0.609548173535927 0.962181413740598 PSMC5 1 GO:0072010 glomerular epithelium development 1/719 24/18722 0.609548173535927 0.962181413740598 CD24 1 GO:0090023 positive regulation of neutrophil chemotaxis 1/719 24/18722 0.609548173535927 0.962181413740598 C1QBP 1 GO:1900373 positive regulation of purine nucleotide biosynthetic process 1/719 24/18722 0.609548173535927 0.962181413740598 ENO1 1 GO:1903428 positive regulation of reactive oxygen species biosynthetic process 1/719 24/18722 0.609548173535927 0.962181413740598 PARK7 1 GO:2000209 regulation of anoikis 1/719 24/18722 0.609548173535927 0.962181413740598 CAV1 1 GO:0007565 female pregnancy 7/719 193/18722 0.614570662177741 0.969512286462079 RPL29/SOD1/COMT/C1QBP/PRDX3/AKR1B1/UMPS 7 GO:1905897 regulation of response to endoplasmic reticulum stress 3/719 82/18722 0.614695971754269 0.969512286462079 PARK7/CAV1/BAX 3 GO:0032946 positive regulation of mononuclear cell proliferation 5/719 138/18722 0.615407053460467 0.970236345545782 HMGB1/RPS3/MIF/CD24/PNP 5 GO:0021537 telencephalon development 9/719 248/18722 0.616063254019677 0.970873322953645 UQCRQ/NME1/ANXA3/EZH2/C12orf57/ATIC/MKKS/BNIP3/BAX 9 GO:0030520 intracellular estrogen receptor signaling pathway 2/719 54/18722 0.619482515600531 0.975087187595548 PARP1/PHB2 2 GO:0072698 protein localization to microtubule cytoskeleton 2/719 54/18722 0.619482515600531 0.975087187595548 AURKA/NSFL1C 2 GO:0034767 positive regulation of ion transmembrane transport 6/719 167/18722 0.623298781555333 0.975087187595548 CALM2/GSTO1/CALM1/NDUFA4/COX17/BAX 6 GO:1903034 regulation of response to wounding 6/719 167/18722 0.623298781555333 0.975087187595548 HMGB1/PRDX2/ACTG1/ANXA2/CAV1/HRAS 6 GO:0000244 spliceosomal tri-snRNP complex assembly 1/719 25/18722 0.624562338859902 0.975087187595548 LSM2 1 GO:0016540 protein autoprocessing 1/719 25/18722 0.624562338859902 0.975087187595548 PARP1 1 GO:0021846 cell proliferation in forebrain 1/719 25/18722 0.624562338859902 0.975087187595548 RRM1 1 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 1/719 25/18722 0.624562338859902 0.975087187595548 PRDX2 1 GO:0032400 melanosome localization 1/719 25/18722 0.624562338859902 0.975087187595548 MKKS 1 GO:0032469 endoplasmic reticulum calcium ion homeostasis 1/719 25/18722 0.624562338859902 0.975087187595548 BAX 1 GO:0032925 regulation of activin receptor signaling pathway 1/719 25/18722 0.624562338859902 0.975087187595548 CSNK2B 1 GO:0033622 integrin activation 1/719 25/18722 0.624562338859902 0.975087187595548 ITGB1BP1 1 GO:0034389 lipid droplet organization 1/719 25/18722 0.624562338859902 0.975087187595548 PPIA 1 GO:0042730 fibrinolysis 1/719 25/18722 0.624562338859902 0.975087187595548 ANXA2 1 GO:0042832 defense response to protozoan 1/719 25/18722 0.624562338859902 0.975087187595548 HRAS 1 GO:0044550 secondary metabolite biosynthetic process 1/719 25/18722 0.624562338859902 0.975087187595548 DDT 1 GO:0046949 fatty-acyl-CoA biosynthetic process 1/719 25/18722 0.624562338859902 0.975087187595548 SLC25A1 1 GO:0051307 meiotic chromosome separation 1/719 25/18722 0.624562338859902 0.975087187595548 TOP2A 1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 1/719 25/18722 0.624562338859902 0.975087187595548 SUB1 1 GO:0061436 establishment of skin barrier 1/719 25/18722 0.624562338859902 0.975087187595548 STMN1 1 GO:0086013 membrane repolarization during cardiac muscle cell action potential 1/719 25/18722 0.624562338859902 0.975087187595548 YWHAE 1 GO:1900078 positive regulation of cellular response to insulin stimulus 1/719 25/18722 0.624562338859902 0.975087187595548 NUCKS1 1 GO:1905564 positive regulation of vascular endothelial cell proliferation 1/719 25/18722 0.624562338859902 0.975087187595548 HMGB1 1 GO:1901653 cellular response to peptide 13/719 359/18722 0.625578617219507 0.976277939317025 GSTP1/CCNA2/CDC6/NUCKS1/PKM/RPL23/CAV1/AKR1B1/APEX1/CDK4/PARP1/APRT/ID1 13 GO:0007015 actin filament organization 16/719 441/18722 0.628323405897655 0.978812413031177 STMN1/S100A10/PFN1/ALDOA/PDLIM1/ACTG1/CFL1/DSTN/DIAPH3/ARPC1A/ARPC5/RHOC/ARPC5L/MKKS/ID1/ITGB1BP1 16 GO:0032609 interferon-gamma production 4/719 112/18722 0.628350094809559 0.978812413031177 HMGB1/HSPD1/C1QBP/HRAS 4 GO:0032649 regulation of interferon-gamma production 4/719 112/18722 0.628350094809559 0.978812413031177 HMGB1/HSPD1/C1QBP/HRAS 4 GO:0043406 positive regulation of MAP kinase activity 4/719 112/18722 0.628350094809559 0.978812413031177 RPS3/CD24/EZH2/HRAS 4 GO:0002833 positive regulation of response to biotic stimulus 6/719 168/18722 0.629066266074675 0.978812413031177 HMGB2/HMGB1/RPS19/HSPD1/HSP90AA1/XRCC6 6 GO:0043331 response to dsRNA 2/719 55/18722 0.629490788224726 0.978812413031177 NPM1/CAV1 2 GO:0045620 negative regulation of lymphocyte differentiation 2/719 55/18722 0.629490788224726 0.978812413031177 HMGB1/PRDX2 2 GO:0046164 alcohol catabolic process 2/719 55/18722 0.629490788224726 0.978812413031177 TPI1/IMPA2 2 GO:1905517 macrophage migration 2/719 55/18722 0.629490788224726 0.978812413031177 MIF/DDT 2 GO:0090276 regulation of peptide hormone secretion 7/719 196/18722 0.630713868573515 0.980318285832876 PHPT1/DYNLL1/MPC2/UQCC2/ENY2/HADH/ENSA 7 GO:0010660 regulation of muscle cell apoptotic process 3/719 84/18722 0.631009256265341 0.980381612841632 CDKN2A/DNMT1/BNIP3 3 GO:0016241 regulation of macroautophagy 5/719 141/18722 0.634348432048074 0.980588653394158 GAPDH/SLC25A5/VDAC1/RHEB/BNIP3 5 GO:0055013 cardiac muscle cell development 3/719 85/18722 0.638984477521844 0.980588653394158 CDK1/CCNB1/PIN1 3 GO:0055072 iron ion homeostasis 3/719 85/18722 0.638984477521844 0.980588653394158 SOD1/GLRX3/ISCU 3 GO:0071277 cellular response to calcium ion 3/719 85/18722 0.638984477521844 0.980588653394158 CACYBP/ECT2/PPIF 3 GO:0072384 organelle transport along microtubule 3/719 85/18722 0.638984477521844 0.980588653394158 UBB/HSBP1/UXT 3 GO:0001562 response to protozoan 1/719 26/18722 0.638999931968942 0.980588653394158 HRAS 1 GO:0006517 protein deglycosylation 1/719 26/18722 0.638999931968942 0.980588653394158 PARK7 1 GO:0006706 steroid catabolic process 1/719 26/18722 0.638999931968942 0.980588653394158 YWHAH 1 GO:0009435 NAD biosynthetic process 1/719 26/18722 0.638999931968942 0.980588653394158 QPRT 1 GO:0010875 positive regulation of cholesterol efflux 1/719 26/18722 0.638999931968942 0.980588653394158 CAV1 1 GO:0014829 vascular associated smooth muscle contraction 1/719 26/18722 0.638999931968942 0.980588653394158 MKKS 1 GO:0015985 energy coupled proton transport, down electrochemical gradient 1/719 26/18722 0.638999931968942 0.980588653394158 STOML2 1 GO:0015986 ATP synthesis coupled proton transport 1/719 26/18722 0.638999931968942 0.980588653394158 STOML2 1 GO:0018027 peptidyl-lysine dimethylation 1/719 26/18722 0.638999931968942 0.980588653394158 PIH1D1 1 GO:0021680 cerebellar Purkinje cell layer development 1/719 26/18722 0.638999931968942 0.980588653394158 UQCRQ 1 GO:0021952 central nervous system projection neuron axonogenesis 1/719 26/18722 0.638999931968942 0.980588653394158 C12orf57 1 GO:0032682 negative regulation of chemokine production 1/719 26/18722 0.638999931968942 0.980588653394158 GSTP1 1 GO:0033522 histone H2A ubiquitination 1/719 26/18722 0.638999931968942 0.980588653394158 SKP1 1 GO:0034063 stress granule assembly 1/719 26/18722 0.638999931968942 0.980588653394158 RPS23 1 GO:0045745 positive regulation of G protein-coupled receptor signaling pathway 1/719 26/18722 0.638999931968942 0.980588653394158 PHB 1 GO:0046639 negative regulation of alpha-beta T cell differentiation 1/719 26/18722 0.638999931968942 0.980588653394158 HMGB1 1 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 1/719 26/18722 0.638999931968942 0.980588653394158 RPS3 1 GO:0051350 negative regulation of lyase activity 1/719 26/18722 0.638999931968942 0.980588653394158 PHPT1 1 GO:0051875 pigment granule localization 1/719 26/18722 0.638999931968942 0.980588653394158 MKKS 1 GO:0060544 regulation of necroptotic process 1/719 26/18722 0.638999931968942 0.980588653394158 CAV1 1 GO:0099637 neurotransmitter receptor transport 1/719 26/18722 0.638999931968942 0.980588653394158 NSG1 1 GO:1904861 excitatory synapse assembly 1/719 26/18722 0.638999931968942 0.980588653394158 ZDHHC12 1 GO:1905063 regulation of vascular associated smooth muscle cell differentiation 1/719 26/18722 0.638999931968942 0.980588653394158 DNMT1 1 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 2/719 56/18722 0.639292862342685 0.980588653394158 EXOSC8/POLR2G 2 GO:0046456 icosanoid biosynthetic process 2/719 56/18722 0.639292862342685 0.980588653394158 MIF/PTGES3 2 GO:0048255 mRNA stabilization 2/719 56/18722 0.639292862342685 0.980588653394158 YBX1/HNRNPD 2 GO:0071385 cellular response to glucocorticoid stimulus 2/719 56/18722 0.639292862342685 0.980588653394158 GSTP1/UBE2L3 2 GO:0050729 positive regulation of inflammatory response 5/719 142/18722 0.640533724802425 0.982100693145893 RPS19/PARK7/HSPD1/VAMP8/DDT 5 GO:0021987 cerebral cortex development 4/719 114/18722 0.642186998660228 0.984243608615397 ATIC/MKKS/BNIP3/BAX 4 GO:0051048 negative regulation of secretion 6/719 171/18722 0.646057334104014 0.988746867620951 COMT/IDH2/ENY2/VAMP8/HADH/PNKD 6 GO:0042098 T cell proliferation 7/719 199/18722 0.646469621953459 0.988746867620951 HMGB1/PRDX2/RPS3/RPS6/CD24/PNP/BAX 7 GO:0030010 establishment of cell polarity 5/719 143/18722 0.646653720796867 0.988746867620951 MAD2L1/DYNLT1/HSP90AB1/HSP90AA1/NSFL1C 5 GO:0009798 axis specification 3/719 86/18722 0.646838096156955 0.988746867620951 AURKA/HSPB11/MDFI 3 GO:0022406 membrane docking 3/719 86/18722 0.646838096156955 0.988746867620951 CALM1/VAMP8/SNX3 3 GO:0006695 cholesterol biosynthetic process 2/719 57/18722 0.648889792090716 0.988746867620951 SOD1/FDPS 2 GO:0016447 somatic recombination of immunoglobulin gene segments 2/719 57/18722 0.648889792090716 0.988746867620951 UNG/HSPD1 2 GO:0050879 multicellular organismal movement 2/719 57/18722 0.648889792090716 0.988746867620951 GSTO1/C12orf57 2 GO:0050881 musculoskeletal movement 2/719 57/18722 0.648889792090716 0.988746867620951 GSTO1/C12orf57 2 GO:0050891 multicellular organismal water homeostasis 2/719 57/18722 0.648889792090716 0.988746867620951 STMN1/AKR1B1 2 GO:0051155 positive regulation of striated muscle cell differentiation 2/719 57/18722 0.648889792090716 0.988746867620951 MORF4L2/PIN1 2 GO:0097120 receptor localization to synapse 2/719 57/18722 0.648889792090716 0.988746867620951 NSG1/HRAS 2 GO:1902653 secondary alcohol biosynthetic process 2/719 57/18722 0.648889792090716 0.988746867620951 SOD1/FDPS 2 GO:0046916 cellular transition metal ion homeostasis 4/719 115/18722 0.648977489474842 0.988746867620951 MT2A/SOD1/GLRX3/ISCU 4 GO:0051209 release of sequestered calcium ion into cytosol 4/719 115/18722 0.648977489474842 0.988746867620951 CALM2/GSTO1/CALM1/BAX 4 GO:0002221 pattern recognition receptor signaling pathway 6/719 172/18722 0.65161541574044 0.989995982263169 HMGB1/HSPD1/C1QBP/CAV1/PHB/PHB2 6 GO:0002791 regulation of peptide secretion 7/719 200/18722 0.651633140508028 0.989995982263169 PHPT1/DYNLL1/MPC2/UQCC2/ENY2/HADH/ENSA 7 GO:0010586 miRNA metabolic process 1/719 27/18722 0.652883064666542 0.989995982263169 HRAS 1 GO:0010894 negative regulation of steroid biosynthetic process 1/719 27/18722 0.652883064666542 0.989995982263169 SOD1 1 GO:0033561 regulation of water loss via skin 1/719 27/18722 0.652883064666542 0.989995982263169 STMN1 1 GO:0034143 regulation of toll-like receptor 4 signaling pathway 1/719 27/18722 0.652883064666542 0.989995982263169 HMGB1 1 GO:0034698 response to gonadotropin 1/719 27/18722 0.652883064666542 0.989995982263169 CCNA2 1 GO:0048520 positive regulation of behavior 1/719 27/18722 0.652883064666542 0.989995982263169 CFAP20 1 GO:0060333 interferon-gamma-mediated signaling pathway 1/719 27/18722 0.652883064666542 0.989995982263169 HSP90AB1 1 GO:0071624 positive regulation of granulocyte chemotaxis 1/719 27/18722 0.652883064666542 0.989995982263169 C1QBP 1 GO:1902914 regulation of protein polyubiquitination 1/719 27/18722 0.652883064666542 0.989995982263169 PPIA 1 GO:1903421 regulation of synaptic vesicle recycling 1/719 27/18722 0.652883064666542 0.989995982263169 CALM1 1 GO:0048041 focal adhesion assembly 3/719 87/18722 0.654569783387342 0.99177239907173 S100A10/ACTG1/ITGB1BP1 3 GO:1901879 regulation of protein depolymerization 3/719 87/18722 0.654569783387342 0.99177239907173 TPX2/DSTN/CKAP2 3 GO:0043200 response to amino acid 4/719 116/18722 0.655681945022646 0.992676165291855 PCNA/GSTP1/HNRNPD/DNMT1 4 GO:0051283 negative regulation of sequestering of calcium ion 4/719 116/18722 0.655681945022646 0.992676165291855 CALM2/GSTO1/CALM1/BAX 4 GO:0001954 positive regulation of cell-matrix adhesion 2/719 58/18722 0.65828285456604 0.994267944322971 S100A10/ITGB1BP1 2 GO:0010043 response to zinc ion 2/719 58/18722 0.65828285456604 0.994267944322971 MT2A/PARP1 2 GO:0043506 regulation of JUN kinase activity 2/719 58/18722 0.65828285456604 0.994267944322971 GSTP1/RPS3 2 GO:0043525 positive regulation of neuron apoptotic process 2/719 58/18722 0.65828285456604 0.994267944322971 PIN1/BAX 2 GO:0044380 protein localization to cytoskeleton 2/719 58/18722 0.65828285456604 0.994267944322971 AURKA/NSFL1C 2 GO:0097035 regulation of membrane lipid distribution 2/719 58/18722 0.65828285456604 0.994267944322971 PRELID1/TRIAP1 2 GO:0090087 regulation of peptide transport 7/719 202/18722 0.661824980884524 0.998830629789567 PHPT1/DYNLL1/MPC2/UQCC2/ENY2/HADH/ENSA 7 GO:0001659 temperature homeostasis 6/719 174/18722 0.662570279248264 0.998830629789567 GNAS/CAV1/HADH/RHEB/FH/ID1 6 GO:0045619 regulation of lymphocyte differentiation 6/719 174/18722 0.662570279248264 0.998830629789567 HMGB1/PRDX2/SOD1/PRELID1/XRCC6/PNP 6 GO:0007043 cell-cell junction assembly 5/719 146/18722 0.664616667777238 0.998830629789567 ACTG1/ARL2/CAV1/ECT2/RHOC 5 GO:0045580 regulation of T cell differentiation 5/719 146/18722 0.664616667777238 0.998830629789567 HMGB1/PRDX2/SOD1/PRELID1/PNP 5 GO:0046394 carboxylic acid biosynthetic process 11/719 314/18722 0.664913580806034 0.998830629789567 GSTP1/MIF/PTGES3/DHFR/PARK7/GPX4/NDUFAB1/ADI1/EIF6/PCBD1/HSD17B10 11 GO:0002507 tolerance induction 1/719 28/18722 0.666233001896002 0.998830629789567 HMGB1 1 GO:0002675 positive regulation of acute inflammatory response 1/719 28/18722 0.666233001896002 0.998830629789567 PARK7 1 GO:0008299 isoprenoid biosynthetic process 1/719 28/18722 0.666233001896002 0.998830629789567 FDPS 1 GO:0031342 negative regulation of cell killing 1/719 28/18722 0.666233001896002 0.998830629789567 HSP90AB1 1 GO:0031440 regulation of mRNA 3'-end processing 1/719 28/18722 0.666233001896002 0.998830629789567 CCNB1 1 GO:0032801 receptor catabolic process 1/719 28/18722 0.666233001896002 0.998830629789567 ANXA2 1 GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT 1/719 28/18722 0.666233001896002 0.998830629789567 CAV1 1 GO:0060259 regulation of feeding behavior 1/719 28/18722 0.666233001896002 0.998830629789567 CFAP20 1 GO:0071280 cellular response to copper ion 1/719 28/18722 0.666233001896002 0.998830629789567 MT2A 1 GO:0080111 DNA demethylation 1/719 28/18722 0.666233001896002 0.998830629789567 APEX1 1 GO:1902624 positive regulation of neutrophil migration 1/719 28/18722 0.666233001896002 0.998830629789567 C1QBP 1 GO:1903649 regulation of cytoplasmic transport 1/719 28/18722 0.666233001896002 0.998830629789567 SNX3 1 GO:1904046 negative regulation of vascular endothelial growth factor production 1/719 28/18722 0.666233001896002 0.998830629789567 NUTF2 1 GO:0006767 water-soluble vitamin metabolic process 2/719 59/18722 0.667473531194833 0.999134173833634 GSTO1/DHFR 2 GO:0019369 arachidonic acid metabolic process 2/719 59/18722 0.667473531194833 0.999134173833634 PTGES3/GPX4 2 GO:0030042 actin filament depolymerization 2/719 59/18722 0.667473531194833 0.999134173833634 CFL1/DSTN 2 GO:0043407 negative regulation of MAP kinase activity 2/719 59/18722 0.667473531194833 0.999134173833634 GSTP1/CAV1 2 GO:0051282 regulation of sequestering of calcium ion 4/719 118/18722 0.668831013040956 0.999999985974598 CALM2/GSTO1/CALM1/BAX 4 GO:0071346 cellular response to interferon-gamma 4/719 118/18722 0.668831013040956 0.999999985974598 GAPDH/RPL13A/ACTG1/HSP90AB1 4 GO:0010657 muscle cell apoptotic process 3/719 89/18722 0.669666657615088 0.999999985974598 CDKN2A/DNMT1/BNIP3 3 GO:0014910 regulation of smooth muscle cell migration 3/719 89/18722 0.669666657615088 0.999999985974598 GSTP1/S100A11/APEX1 3 GO:0060041 retina development in camera-type eye 5/719 147/18722 0.670470460893417 0.999999985974598 RPL24/RRM1/IMPDH2/ACTL6A/BAX 5 GO:1903531 negative regulation of secretion by cell 5/719 147/18722 0.670470460893417 0.999999985974598 IDH2/ENY2/VAMP8/HADH/PNKD 5 GO:0016053 organic acid biosynthetic process 11/719 316/18722 0.672987032686606 0.999999985974598 GSTP1/MIF/PTGES3/DHFR/PARK7/GPX4/NDUFAB1/ADI1/EIF6/PCBD1/HSD17B10 11 GO:0014074 response to purine-containing compound 5/719 148/18722 0.676256689857706 0.999999985974598 LDHA/SOD1/NME1/HSPD1/APEX1 5 GO:0033866 nucleoside bisphosphate biosynthetic process 2/719 60/18722 0.676463490199132 0.999999985974598 MPC2/SLC25A1 2 GO:0034030 ribonucleoside bisphosphate biosynthetic process 2/719 60/18722 0.676463490199132 0.999999985974598 MPC2/SLC25A1 2 GO:0034033 purine nucleoside bisphosphate biosynthetic process 2/719 60/18722 0.676463490199132 0.999999985974598 MPC2/SLC25A1 2 GO:0060038 cardiac muscle cell proliferation 2/719 60/18722 0.676463490199132 0.999999985974598 CDK1/CCNB1 2 GO:0061951 establishment of protein localization to plasma membrane 2/719 60/18722 0.676463490199132 0.999999985974598 KRT18/NSG1 2 GO:1903670 regulation of sprouting angiogenesis 2/719 60/18722 0.676463490199132 0.999999985974598 HMGB1/PKM 2 GO:0048477 oogenesis 3/719 90/18722 0.677031778887925 0.999999985974598 RPS6/CCNB1/AURKA 3 GO:0043405 regulation of MAP kinase activity 6/719 177/18722 0.678593265973313 0.999999985974598 GSTP1/RPS3/CD24/EZH2/CAV1/HRAS 6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 1/719 29/18722 0.679070194130771 0.999999985974598 POLR2G 1 GO:0001773 myeloid dendritic cell activation 1/719 29/18722 0.679070194130771 0.999999985974598 HMGB1 1 GO:0002068 glandular epithelial cell development 1/719 29/18722 0.679070194130771 0.999999985974598 RHEB 1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus 1/719 29/18722 0.679070194130771 0.999999985974598 PSMB4 1 GO:0003309 type B pancreatic cell differentiation 1/719 29/18722 0.679070194130771 0.999999985974598 RHEB 1 GO:0005979 regulation of glycogen biosynthetic process 1/719 29/18722 0.679070194130771 0.999999985974598 PPP1CA 1 GO:0010390 histone monoubiquitination 1/719 29/18722 0.679070194130771 0.999999985974598 SKP1 1 GO:0010955 negative regulation of protein processing 1/719 29/18722 0.679070194130771 0.999999985974598 BCL2L12 1 GO:0010962 regulation of glucan biosynthetic process 1/719 29/18722 0.679070194130771 0.999999985974598 PPP1CA 1 GO:0022011 myelination in peripheral nervous system 1/719 29/18722 0.679070194130771 0.999999985974598 SOD1 1 GO:0032292 peripheral nervous system axon ensheathment 1/719 29/18722 0.679070194130771 0.999999985974598 SOD1 1 GO:0032366 intracellular sterol transport 1/719 29/18722 0.679070194130771 0.999999985974598 ANXA2 1 GO:0032367 intracellular cholesterol transport 1/719 29/18722 0.679070194130771 0.999999985974598 ANXA2 1 GO:0035066 positive regulation of histone acetylation 1/719 29/18722 0.679070194130771 0.999999985974598 PIH1D1 1 GO:0040018 positive regulation of multicellular organism growth 1/719 29/18722 0.679070194130771 0.999999985974598 MKKS 1 GO:0043153 entrainment of circadian clock by photoperiod 1/719 29/18722 0.679070194130771 0.999999985974598 PPP1CA 1 GO:0048265 response to pain 1/719 29/18722 0.679070194130771 0.999999985974598 COMT 1 GO:0062098 regulation of programmed necrotic cell death 1/719 29/18722 0.679070194130771 0.999999985974598 CAV1 1 GO:0090025 regulation of monocyte chemotaxis 1/719 29/18722 0.679070194130771 0.999999985974598 HMGB1 1 GO:0095500 acetylcholine receptor signaling pathway 1/719 29/18722 0.679070194130771 0.999999985974598 LY6E 1 GO:1902430 negative regulation of amyloid-beta formation 1/719 29/18722 0.679070194130771 0.999999985974598 PIN1 1 GO:1903318 negative regulation of protein maturation 1/719 29/18722 0.679070194130771 0.999999985974598 BCL2L12 1 GO:1903902 positive regulation of viral life cycle 1/719 29/18722 0.679070194130771 0.999999985974598 KPNA2 1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining 1/719 29/18722 0.679070194130771 0.999999985974598 DEK 1 GO:0071375 cellular response to peptide hormone stimulus 10/719 290/18722 0.680387466388512 0.999999985974598 GSTP1/CCNA2/CDC6/NUCKS1/PKM/CAV1/APEX1/CDK4/PARP1/APRT 10 GO:0071901 negative regulation of protein serine/threonine kinase activity 4/719 120/18722 0.681631433871805 0.999999985974598 GSTP1/PKIB/CAV1/CDKN2A 4 GO:0032368 regulation of lipid transport 5/719 149/18722 0.681975041412719 0.999999985974598 DBI/ANXA2/PRELID1/TRIAP1/CAV1 5 GO:0035265 organ growth 6/719 178/18722 0.683823728752273 0.999999985974598 CDK1/CCNB1/SOD1/LY6E/DUSP9/PIN1 6 GO:0055006 cardiac cell development 3/719 91/18722 0.684274826128968 0.999999985974598 CDK1/CCNB1/PIN1 3 GO:0016236 macroautophagy 10/719 291/18722 0.684505452038345 0.999999985974598 GAPDH/SLC25A5/CALM1/VDAC1/VAMP8/RHEB/PHB2/BNIP3/UFC1/NSFL1C 10 GO:0030865 cortical cytoskeleton organization 2/719 61/18722 0.685254570105848 0.999999985974598 ECT2/RHOC 2 GO:0043030 regulation of macrophage activation 2/719 61/18722 0.685254570105848 0.999999985974598 MIF/HSPD1 2 GO:0071384 cellular response to corticosteroid stimulus 2/719 61/18722 0.685254570105848 0.999999985974598 GSTP1/UBE2L3 2 GO:0070665 positive regulation of leukocyte proliferation 5/719 150/18722 0.687625246297721 0.999999985974598 HMGB1/RPS3/MIF/CD24/PNP 5 GO:0043500 muscle adaptation 4/719 121/18722 0.687900332698285 0.999999985974598 EZH2/PARP1/PIN1/GLRX3 4 GO:0006941 striated muscle contraction 6/719 179/18722 0.68899844209223 0.999999985974598 CALM2/GSTO1/ALDOA/CALM1/CAV1/C12orf57 6 GO:0030072 peptide hormone secretion 8/719 236/18722 0.68964963906975 0.999999985974598 PHPT1/DYNLL1/PARK7/MPC2/UQCC2/ENY2/HADH/ENSA 8 GO:1903351 cellular response to dopamine 3/719 92/18722 0.691396028866715 0.999999985974598 GNAS/NSG1/ID1 3 GO:0003299 muscle hypertrophy in response to stress 1/719 30/18722 0.691414308527603 0.999999985974598 EZH2 1 GO:0006884 cell volume homeostasis 1/719 30/18722 0.691414308527603 0.999999985974598 NPM1 1 GO:0008209 androgen metabolic process 1/719 30/18722 0.691414308527603 0.999999985974598 HSD17B10 1 GO:0014887 cardiac muscle adaptation 1/719 30/18722 0.691414308527603 0.999999985974598 EZH2 1 GO:0014898 cardiac muscle hypertrophy in response to stress 1/719 30/18722 0.691414308527603 0.999999985974598 EZH2 1 GO:0017145 stem cell division 1/719 30/18722 0.691414308527603 0.999999985974598 CDK2AP2 1 GO:0043032 positive regulation of macrophage activation 1/719 30/18722 0.691414308527603 0.999999985974598 HSPD1 1 GO:0043304 regulation of mast cell degranulation 1/719 30/18722 0.691414308527603 0.999999985974598 VAMP8 1 GO:0045939 negative regulation of steroid metabolic process 1/719 30/18722 0.691414308527603 0.999999985974598 SOD1 1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway 1/719 30/18722 0.691414308527603 0.999999985974598 PHPT1 1 GO:0060603 mammary gland duct morphogenesis 1/719 30/18722 0.691414308527603 0.999999985974598 PHB2 1 GO:0070229 negative regulation of lymphocyte apoptotic process 1/719 30/18722 0.691414308527603 0.999999985974598 AURKB 1 GO:0099068 postsynapse assembly 1/719 30/18722 0.691414308527603 0.999999985974598 ZDHHC12 1 GO:1900101 regulation of endoplasmic reticulum unfolded protein response 1/719 30/18722 0.691414308527603 0.999999985974598 BAX 1 GO:2000648 positive regulation of stem cell proliferation 1/719 30/18722 0.691414308527603 0.999999985974598 CCNE1 1 GO:0030902 hindbrain development 5/719 151/18722 0.693207078067395 0.999999985974598 UQCRQ/HNRNPD/PSMG1/EZH2/ATIC 5 GO:0007588 excretion 2/719 62/18722 0.693848764243901 0.999999985974598 COMT/GRHPR 2 GO:0031124 mRNA 3'-end processing 2/719 62/18722 0.693848764243901 0.999999985974598 CCNB1/SLBP 2 GO:0032613 interleukin-10 production 2/719 62/18722 0.693848764243901 0.999999985974598 HMGB1/HSPD1 2 GO:0032653 regulation of interleukin-10 production 2/719 62/18722 0.693848764243901 0.999999985974598 HMGB1/HSPD1 2 GO:0032757 positive regulation of interleukin-8 production 2/719 62/18722 0.693848764243901 0.999999985974598 HMGB1/PARK7 2 GO:0045576 mast cell activation 2/719 62/18722 0.693848764243901 0.999999985974598 S100A13/VAMP8 2 GO:0048488 synaptic vesicle endocytosis 2/719 62/18722 0.693848764243901 0.999999985974598 CALM1/ACTG1 2 GO:0060135 maternal process involved in female pregnancy 2/719 62/18722 0.693848764243901 0.999999985974598 PRDX3/AKR1B1 2 GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 2/719 62/18722 0.693848764243901 0.999999985974598 CSNK2B/PIN1 2 GO:0140238 presynaptic endocytosis 2/719 62/18722 0.693848764243901 0.999999985974598 CALM1/ACTG1 2 GO:0002688 regulation of leukocyte chemotaxis 4/719 122/18722 0.694081515072141 0.999999985974598 HMGB1/MIF/C1QBP/DDT 4 GO:0051208 sequestering of calcium ion 4/719 122/18722 0.694081515072141 0.999999985974598 CALM2/GSTO1/CALM1/BAX 4 GO:0048660 regulation of smooth muscle cell proliferation 6/719 180/18722 0.694117162684628 0.999999985974598 GSTP1/COMT/XRCC6/AKR1B1/PHB/DNMT1 6 GO:0033273 response to vitamin 3/719 93/18722 0.698395712040597 0.999999985974598 TYMS/GSTP1/CCND1 3 GO:0051591 response to cAMP 3/719 93/18722 0.698395712040597 0.999999985974598 LDHA/NME1/APEX1 3 GO:1903350 response to dopamine 3/719 93/18722 0.698395712040597 0.999999985974598 GNAS/NSG1/ID1 3 GO:0042391 regulation of membrane potential 15/719 434/18722 0.698876231231746 0.999999985974598 CALM1/YWHAH/SOD1/PARK7/PRELID1/UBB/YWHAE/PRDX3/CAV1/STOML2/PARP1/SUMO1/SLC29A1/BNIP3/BAX 15 GO:0010811 positive regulation of cell-substrate adhesion 4/719 123/18722 0.700174925438222 0.999999985974598 S100A10/ARL2/C1QBP/ITGB1BP1 4 GO:0030168 platelet activation 4/719 123/18722 0.700174925438222 0.999999985974598 PPIA/ACTG1/GNAS/FIBP 4 GO:0045143 homologous chromosome segregation 2/719 63/18722 0.702248206178066 0.999999985974598 PTTG1/CCNE1 2 GO:0050854 regulation of antigen receptor-mediated signaling pathway 2/719 63/18722 0.702248206178066 0.999999985974598 RPS3/PHPT1 2 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 2/719 63/18722 0.702248206178066 0.999999985974598 PARK7/BAX 2 GO:1902373 negative regulation of mRNA catabolic process 2/719 63/18722 0.702248206178066 0.999999985974598 YBX1/HNRNPD 2 GO:0001782 B cell homeostasis 1/719 31/18722 0.703284258889718 0.999999985974598 BAX 1 GO:0002230 positive regulation of defense response to virus by host 1/719 31/18722 0.703284258889718 0.999999985974598 HSP90AA1 1 GO:0007190 activation of adenylate cyclase activity 1/719 31/18722 0.703284258889718 0.999999985974598 CALM1 1 GO:0033006 regulation of mast cell activation involved in immune response 1/719 31/18722 0.703284258889718 0.999999985974598 VAMP8 1 GO:0034472 snRNA 3'-end processing 1/719 31/18722 0.703284258889718 0.999999985974598 EXOSC8 1 GO:0035510 DNA dealkylation 1/719 31/18722 0.703284258889718 0.999999985974598 APEX1 1 GO:0042133 neurotransmitter metabolic process 1/719 31/18722 0.703284258889718 0.999999985974598 COMT 1 GO:0048384 retinoic acid receptor signaling pathway 1/719 31/18722 0.703284258889718 0.999999985974598 EZH2 1 GO:0060390 regulation of SMAD protein signal transduction 1/719 31/18722 0.703284258889718 0.999999985974598 PARP1 1 GO:0061099 negative regulation of protein tyrosine kinase activity 1/719 31/18722 0.703284258889718 0.999999985974598 CAV1 1 GO:0070633 transepithelial transport 1/719 31/18722 0.703284258889718 0.999999985974598 ACTG1 1 GO:0071711 basement membrane organization 1/719 31/18722 0.703284258889718 0.999999985974598 CAV1 1 GO:0097106 postsynaptic density organization 1/719 31/18722 0.703284258889718 0.999999985974598 ZDHHC12 1 GO:1905144 response to acetylcholine 1/719 31/18722 0.703284258889718 0.999999985974598 LY6E 1 GO:1905145 cellular response to acetylcholine 1/719 31/18722 0.703284258889718 0.999999985974598 LY6E 1 GO:2000144 positive regulation of DNA-templated transcription, initiation 1/719 31/18722 0.703284258889718 0.999999985974598 SUB1 1 GO:0034765 regulation of ion transmembrane transport 17/719 491/18722 0.704183191928819 0.999999985974598 CALM2/GSTO1/CALM1/YWHAH/PARK7/VDAC1/NDUFA4/YWHAE/COX17/CAV1/YWHAQ/C4orf3/PPIF/PHB2/SUMO1/ISCU/BAX 17 GO:0050708 regulation of protein secretion 9/719 268/18722 0.705616337875412 0.999999985974598 PPIA/PHPT1/DYNLL1/MPC2/UQCC2/IDH2/ENY2/HADH/ENSA 9 GO:0030856 regulation of epithelial cell differentiation 5/719 154/18722 0.709540687677377 0.999999985974598 CD24/EZH2/CAV1/CCND1/ID1 5 GO:0006940 regulation of smooth muscle contraction 2/719 64/18722 0.710455156030612 0.999999985974598 SOD1/CAV1 2 GO:0016126 sterol biosynthetic process 2/719 64/18722 0.710455156030612 0.999999985974598 SOD1/FDPS 2 GO:0030104 water homeostasis 2/719 64/18722 0.710455156030612 0.999999985974598 STMN1/AKR1B1 2 GO:0030837 negative regulation of actin filament polymerization 2/719 64/18722 0.710455156030612 0.999999985974598 PFN1/MKKS 2 GO:0046579 positive regulation of Ras protein signal transduction 2/719 64/18722 0.710455156030612 0.999999985974598 DYNLT1/HRAS 2 GO:0046888 negative regulation of hormone secretion 2/719 64/18722 0.710455156030612 0.999999985974598 ENY2/HADH 2 GO:0098930 axonal transport 2/719 64/18722 0.710455156030612 0.999999985974598 SOD1/HSBP1 2 GO:0007044 cell-substrate junction assembly 3/719 95/18722 0.712032266227556 0.999999985974598 S100A10/ACTG1/ITGB1BP1 3 GO:0008585 female gonad development 3/719 95/18722 0.712032266227556 0.999999985974598 SOD1/UBB/BAX 3 GO:0048709 oligodendrocyte differentiation 3/719 95/18722 0.712032266227556 0.999999985974598 GSTP1/RHEB/BNIP3 3 GO:0050764 regulation of phagocytosis 3/719 95/18722 0.712032266227556 0.999999985974598 HMGB1/SOD1/SNX3 3 GO:1901379 regulation of potassium ion transmembrane transport 3/719 95/18722 0.712032266227556 0.999999985974598 YWHAE/CAV1/SUMO1 3 GO:0055007 cardiac muscle cell differentiation 4/719 125/18722 0.712098496094094 0.999999985974598 CDK1/CCNB1/CACYBP/PIN1 4 GO:0048659 smooth muscle cell proliferation 6/719 184/18722 0.714028289284066 0.999999985974598 GSTP1/COMT/XRCC6/AKR1B1/PHB/DNMT1 6 GO:0014044 Schwann cell development 1/719 32/18722 0.714698234485368 0.999999985974598 SOD1 1 GO:0019835 cytolysis 1/719 32/18722 0.714698234485368 0.999999985974598 ROMO1 1 GO:0030431 sleep 1/719 32/18722 0.714698234485368 0.999999985974598 SLC29A1 1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 1/719 32/18722 0.714698234485368 0.999999985974598 HSP90AB1 1 GO:0035456 response to interferon-beta 1/719 32/18722 0.714698234485368 0.999999985974598 NDUFA13 1 GO:0035767 endothelial cell chemotaxis 1/719 32/18722 0.714698234485368 0.999999985974598 HMGB1 1 GO:0035883 enteroendocrine cell differentiation 1/719 32/18722 0.714698234485368 0.999999985974598 RHEB 1 GO:0045684 positive regulation of epidermis development 1/719 32/18722 0.714698234485368 0.999999985974598 KRT10 1 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity 1/719 32/18722 0.714698234485368 0.999999985974598 CDKN2A 1 GO:0046475 glycerophospholipid catabolic process 1/719 32/18722 0.714698234485368 0.999999985974598 PRDX6 1 GO:0090022 regulation of neutrophil chemotaxis 1/719 32/18722 0.714698234485368 0.999999985974598 C1QBP 1 GO:1900745 positive regulation of p38MAPK cascade 1/719 32/18722 0.714698234485368 0.999999985974598 PRMT1 1 GO:1901889 negative regulation of cell junction assembly 1/719 32/18722 0.714698234485368 0.999999985974598 ITGB1BP1 1 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/719 32/18722 0.714698234485368 0.999999985974598 PARK7 1 GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 1/719 32/18722 0.714698234485368 0.999999985974598 HSP90AB1 1 GO:1905476 negative regulation of protein localization to membrane 1/719 32/18722 0.714698234485368 0.999999985974598 ITGB1BP1 1 GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 1/719 32/18722 0.714698234485368 0.999999985974598 HMGB1 1 GO:0051147 regulation of muscle cell differentiation 5/719 155/18722 0.714847577556925 0.999999985974598 YBX1/MORF4L2/EZH2/DNMT1/PIN1 5 GO:0002790 peptide secretion 8/719 242/18722 0.715911186424987 0.999999985974598 PHPT1/DYNLL1/PARK7/MPC2/UQCC2/ENY2/HADH/ENSA 8 GO:0022412 cellular process involved in reproduction in multicellular organism 13/719 384/18722 0.718078733354473 0.999999985974598 HMGB2/TOP2A/RPS6/CCNB2/CCNB1/DYNLL1/AURKA/SLIRP/EIF2S2/UBB/RAD51C/MKKS/BAX 13 GO:0043489 RNA stabilization 2/719 65/18722 0.718471987644175 0.999999985974598 YBX1/HNRNPD 2 GO:0045682 regulation of epidermis development 2/719 65/18722 0.718471987644175 0.999999985974598 EZH2/KRT10 2 GO:0060389 pathway-restricted SMAD protein phosphorylation 2/719 65/18722 0.718471987644175 0.999999985974598 CSNK2B/PIN1 2 GO:0071677 positive regulation of mononuclear cell migration 2/719 65/18722 0.718471987644175 0.999999985974598 HMGB1/C1QBP 2 GO:0006637 acyl-CoA metabolic process 3/719 96/18722 0.718670219273549 0.999999985974598 MPC2/NUDT8/SLC25A1 3 GO:0010769 regulation of cell morphogenesis involved in differentiation 3/719 96/18722 0.718670219273549 0.999999985974598 S100A10/C1QBP/ITGB1BP1 3 GO:0015914 phospholipid transport 3/719 96/18722 0.718670219273549 0.999999985974598 DBI/PRELID1/TRIAP1 3 GO:0034620 cellular response to unfolded protein 3/719 96/18722 0.718670219273549 0.999999985974598 HSPD1/CCND1/BAX 3 GO:0035383 thioester metabolic process 3/719 96/18722 0.718670219273549 0.999999985974598 MPC2/NUDT8/SLC25A1 3 GO:0055017 cardiac muscle tissue growth 3/719 96/18722 0.718670219273549 0.999999985974598 CDK1/CCNB1/PIN1 3 GO:1901655 cellular response to ketone 3/719 96/18722 0.718670219273549 0.999999985974598 PARK7/AKR1B1/CDK4 3 GO:0043434 response to peptide hormone 14/719 414/18722 0.724619762051529 0.999999985974598 GSTP1/CCNA2/CDC6/CACYBP/NUCKS1/PKM/CAV1/EIF6/HADH/APEX1/CDK4/PARP1/APRT/CYC1 14 GO:0006721 terpenoid metabolic process 3/719 97/18722 0.725188807422556 0.999999985974598 FDPS/AKR1B1/ADH5 3 GO:0010596 negative regulation of endothelial cell migration 3/719 97/18722 0.725188807422556 0.999999985974598 HMGB1/CSNK2B/ITGB1BP1 3 GO:0035335 peptidyl-tyrosine dephosphorylation 3/719 97/18722 0.725188807422556 0.999999985974598 CDKN3/PGP/ACP1 3 GO:1901216 positive regulation of neuron death 3/719 97/18722 0.725188807422556 0.999999985974598 PARP1/PIN1/BAX 3 GO:0003382 epithelial cell morphogenesis 1/719 33/18722 0.725673727765465 0.999999985974598 RAB25 1 GO:0006891 intra-Golgi vesicle-mediated transport 1/719 33/18722 0.725673727765465 0.999999985974598 COPE 1 GO:0009648 photoperiodism 1/719 33/18722 0.725673727765465 0.999999985974598 PPP1CA 1 GO:0010737 protein kinase A signaling 1/719 33/18722 0.725673727765465 0.999999985974598 MIF 1 GO:0010984 regulation of lipoprotein particle clearance 1/719 33/18722 0.725673727765465 0.999999985974598 ANXA2 1 GO:0018345 protein palmitoylation 1/719 33/18722 0.725673727765465 0.999999985974598 ZDHHC12 1 GO:0032228 regulation of synaptic transmission, GABAergic 1/719 33/18722 0.725673727765465 0.999999985974598 ZDHHC12 1 GO:0050974 detection of mechanical stimulus involved in sensory perception 1/719 33/18722 0.725673727765465 0.999999985974598 MKKS 1 GO:0060122 inner ear receptor cell stereocilium organization 1/719 33/18722 0.725673727765465 0.999999985974598 SOD1 1 GO:0099084 postsynaptic specialization organization 1/719 33/18722 0.725673727765465 0.999999985974598 ZDHHC12 1 GO:1900181 negative regulation of protein localization to nucleus 1/719 33/18722 0.725673727765465 0.999999985974598 SUMO1 1 GO:1901099 negative regulation of signal transduction in absence of ligand 1/719 33/18722 0.725673727765465 0.999999985974598 PRDX2 1 GO:1902275 regulation of chromatin organization 1/719 33/18722 0.725673727765465 0.999999985974598 DNMT1 1 GO:1902992 negative regulation of amyloid precursor protein catabolic process 1/719 33/18722 0.725673727765465 0.999999985974598 PIN1 1 GO:1904030 negative regulation of cyclin-dependent protein kinase activity 1/719 33/18722 0.725673727765465 0.999999985974598 CDKN2A 1 GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 1/719 33/18722 0.725673727765465 0.999999985974598 PRDX2 1 GO:0070371 ERK1 and ERK2 cascade 11/719 330/18722 0.726244035466372 0.999999985974598 HMGB1/CDK1/GSTP1/MIF/DUSP9/PHB/DDT/PHB2/PIN1/HRAS/ITGB1BP1 11 GO:0046626 regulation of insulin receptor signaling pathway 2/719 66/18722 0.726301176541587 0.999999985974598 NUCKS1/CDK4 2 GO:0071300 cellular response to retinoic acid 2/719 66/18722 0.726301176541587 0.999999985974598 NDUFA13/PHB2 2 GO:0008064 regulation of actin polymerization or depolymerization 6/719 187/18722 0.728366112823234 0.999999985974598 PFN1/DSTN/ARPC1A/ARPC5/ARPC5L/MKKS 6 GO:0098656 anion transmembrane transport 8/719 245/18722 0.728476849268233 0.999999985974598 SLC25A5/SLC25A6/SLC25A3/VDAC1/MPC2/VDAC3/VDAC2/SLC25A1 8 GO:0001952 regulation of cell-matrix adhesion 4/719 128/18722 0.72932739449802 0.999999985974598 S100A10/ACTG1/CDKN2A/ITGB1BP1 4 GO:0043502 regulation of muscle adaptation 3/719 98/18722 0.731588759569825 0.999999985974598 PARP1/PIN1/GLRX3 3 GO:0030308 negative regulation of cell growth 6/719 188/18722 0.733031596040223 0.999999985974598 ENO1/RBBP7/CDKN2A/NDUFA13/PHB/NDUFS3 6 GO:0030832 regulation of actin filament length 6/719 188/18722 0.733031596040223 0.999999985974598 PFN1/DSTN/ARPC1A/ARPC5/ARPC5L/MKKS 6 GO:0048814 regulation of dendrite morphogenesis 2/719 67/18722 0.733945288640498 0.999999985974598 YWHAH/ID1 2 GO:0001662 behavioral fear response 1/719 34/18722 0.736227561022281 0.999999985974598 VDAC1 1 GO:0002446 neutrophil mediated immunity 1/719 34/18722 0.736227561022281 0.999999985974598 ANXA3 1 GO:0009649 entrainment of circadian clock 1/719 34/18722 0.736227561022281 0.999999985974598 PPP1CA 1 GO:0010614 negative regulation of cardiac muscle hypertrophy 1/719 34/18722 0.736227561022281 0.999999985974598 GLRX3 1 GO:0019076 viral release from host cell 1/719 34/18722 0.736227561022281 0.999999985974598 PPIA 1 GO:0019320 hexose catabolic process 1/719 34/18722 0.736227561022281 0.999999985974598 ENO1 1 GO:0034383 low-density lipoprotein particle clearance 1/719 34/18722 0.736227561022281 0.999999985974598 ANXA2 1 GO:0035890 exit from host 1/719 34/18722 0.736227561022281 0.999999985974598 PPIA 1 GO:0035891 exit from host cell 1/719 34/18722 0.736227561022281 0.999999985974598 PPIA 1 GO:0044319 wound healing, spreading of cells 1/719 34/18722 0.736227561022281 0.999999985974598 RHOC 1 GO:0048854 brain morphogenesis 1/719 34/18722 0.736227561022281 0.999999985974598 MKKS 1 GO:0070232 regulation of T cell apoptotic process 1/719 34/18722 0.736227561022281 0.999999985974598 PRELID1 1 GO:0086004 regulation of cardiac muscle cell contraction 1/719 34/18722 0.736227561022281 0.999999985974598 CAV1 1 GO:0090075 relaxation of muscle 1/719 34/18722 0.736227561022281 0.999999985974598 SOD1 1 GO:0090505 epiboly involved in wound healing 1/719 34/18722 0.736227561022281 0.999999985974598 RHOC 1 GO:0098751 bone cell development 1/719 34/18722 0.736227561022281 0.999999985974598 ANXA2 1 GO:1904893 negative regulation of receptor signaling pathway via STAT 1/719 34/18722 0.736227561022281 0.999999985974598 CAV1 1 GO:2000758 positive regulation of peptidyl-lysine acetylation 1/719 34/18722 0.736227561022281 0.999999985974598 PIH1D1 1 GO:2000780 negative regulation of double-strand break repair 1/719 34/18722 0.736227561022281 0.999999985974598 RMI2 1 GO:0031667 response to nutrient levels 16/719 474/18722 0.736953999866658 0.999999985974598 TYMS/LDHA/GSTP1/HNRNPA1/PAGE4/SOD1/KRT18/COMT/HAT1/COX4I1/CCND1/NENF/MKKS/TXN2/BNIP3/ENSA 16 GO:0002444 myeloid leukocyte mediated immunity 3/719 99/18722 0.737870871819265 0.999999985974598 ANXA3/S100A13/VAMP8 3 GO:0042100 B cell proliferation 3/719 99/18722 0.737870871819265 0.999999985974598 MIF/HSPD1/BAX 3 GO:0035637 multicellular organismal signaling 5/719 160/18722 0.740349089613458 0.999999985974598 CALM2/CALM1/SOD1/YWHAE/CAV1 5 GO:0060402 calcium ion transport into cytosol 5/719 160/18722 0.740349089613458 0.999999985974598 CALM2/GSTO1/CALM1/CAV1/BAX 5 GO:0033002 muscle cell proliferation 8/719 248/18722 0.740661955880018 0.999999985974598 CDK1/GSTP1/CCNB1/COMT/XRCC6/AKR1B1/PHB/DNMT1 8 GO:0010812 negative regulation of cell-substrate adhesion 2/719 68/18722 0.74140696968273 0.999999985974598 CDKN2A/ITGB1BP1 2 GO:0046637 regulation of alpha-beta T cell differentiation 2/719 68/18722 0.74140696968273 0.999999985974598 HMGB1/PNP 2 GO:0030041 actin filament polymerization 6/719 190/18722 0.742191852865938 0.999999985974598 PFN1/DIAPH3/ARPC1A/ARPC5/ARPC5L/MKKS 6 GO:0099111 microtubule-based transport 6/719 190/18722 0.742191852865938 0.999999985974598 SOD1/UBB/HSBP1/HSPB11/UXT/SSNA1 6 GO:0046545 development of primary female sexual characteristics 3/719 100/18722 0.744036003297313 0.999999985974598 SOD1/UBB/BAX 3 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 8/719 249/18722 0.744638829945749 0.999999985974598 GAPDH/GSTP1/EEF1D/UBE2N/UBE2I/S100A13/ECT2/RHOC 8 GO:0046883 regulation of hormone secretion 8/719 249/18722 0.744638829945749 0.999999985974598 PHPT1/DYNLL1/MPC2/UQCC2/ENY2/VAMP8/HADH/ENSA 8 GO:0031349 positive regulation of defense response 9/719 278/18722 0.744999233028749 0.999999985974598 HMGB2/HMGB1/RPS19/PARK7/HSPD1/HSP90AA1/XRCC6/VAMP8/DDT 9 GO:0044706 multi-multicellular organism process 7/719 220/18722 0.745078926994291 0.999999985974598 RPL29/SOD1/COMT/C1QBP/PRDX3/AKR1B1/UMPS 7 GO:0001893 maternal placenta development 1/719 35/18722 0.746375912029611 0.999999985974598 PRDX3 1 GO:0002209 behavioral defense response 1/719 35/18722 0.746375912029611 0.999999985974598 VDAC1 1 GO:0003298 physiological muscle hypertrophy 1/719 35/18722 0.746375912029611 0.999999985974598 PIN1 1 GO:0003301 physiological cardiac muscle hypertrophy 1/719 35/18722 0.746375912029611 0.999999985974598 PIN1 1 GO:0006471 protein ADP-ribosylation 1/719 35/18722 0.746375912029611 0.999999985974598 PARP1 1 GO:0015695 organic cation transport 1/719 35/18722 0.746375912029611 0.999999985974598 SLC29A1 1 GO:0018149 peptide cross-linking 1/719 35/18722 0.746375912029611 0.999999985974598 KRT10 1 GO:0035633 maintenance of blood-brain barrier 1/719 35/18722 0.746375912029611 0.999999985974598 ACTG1 1 GO:0044273 sulfur compound catabolic process 1/719 35/18722 0.746375912029611 0.999999985974598 NUDT8 1 GO:0045907 positive regulation of vasoconstriction 1/719 35/18722 0.746375912029611 0.999999985974598 CAV1 1 GO:0048821 erythrocyte development 1/719 35/18722 0.746375912029611 0.999999985974598 RPS6 1 GO:0060236 regulation of mitotic spindle organization 1/719 35/18722 0.746375912029611 0.999999985974598 TPX2 1 GO:0061049 cell growth involved in cardiac muscle cell development 1/719 35/18722 0.746375912029611 0.999999985974598 PIN1 1 GO:0070536 protein K63-linked deubiquitination 1/719 35/18722 0.746375912029611 0.999999985974598 PSMD14 1 GO:0071108 protein K48-linked deubiquitination 1/719 35/18722 0.746375912029611 0.999999985974598 PARK7 1 GO:0086005 ventricular cardiac muscle cell action potential 1/719 35/18722 0.746375912029611 0.999999985974598 CAV1 1 GO:0090181 regulation of cholesterol metabolic process 1/719 35/18722 0.746375912029611 0.999999985974598 SOD1 1 GO:0090504 epiboly 1/719 35/18722 0.746375912029611 0.999999985974598 RHOC 1 GO:0098801 regulation of renal system process 1/719 35/18722 0.746375912029611 0.999999985974598 COMT 1 GO:0031060 regulation of histone methylation 2/719 69/18722 0.748688935340216 0.999999985974598 PIH1D1/DNMT1 2 GO:0050688 regulation of defense response to virus 2/719 69/18722 0.748688935340216 0.999999985974598 C1QBP/HSP90AA1 2 GO:0021953 central nervous system neuron differentiation 5/719 162/18722 0.750069168386541 0.999999985974598 UQCRQ/UBB/HSP90AB1/HSP90AA1/C12orf57 5 GO:0060759 regulation of response to cytokine stimulus 5/719 162/18722 0.750069168386541 0.999999985974598 GSTP1/HSP90AB1/CD24/CAV1/TAF9 5 GO:0150115 cell-substrate junction organization 3/719 101/18722 0.750085072110256 0.999999985974598 S100A10/ACTG1/ITGB1BP1 3 GO:0070372 regulation of ERK1 and ERK2 cascade 10/719 309/18722 0.752998093242192 0.999999985974598 HMGB1/GSTP1/MIF/DUSP9/PHB/DDT/PHB2/PIN1/HRAS/ITGB1BP1 10 GO:0003012 muscle system process 15/719 452/18722 0.754921929884462 0.999999985974598 CALM2/GSTO1/ENO1/ALDOA/CALM1/SOD1/MYL6/HSBP1/EZH2/CAV1/C12orf57/PARP1/MKKS/PIN1/GLRX3 15 GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response 2/719 70/18722 0.755793961961272 0.999999985974598 UNG/HSPD1 2 GO:0002548 monocyte chemotaxis 2/719 70/18722 0.755793961961272 0.999999985974598 HMGB1/RPS19 2 GO:0070830 bicellular tight junction assembly 2/719 70/18722 0.755793961961272 0.999999985974598 ARL2/ECT2 2 GO:0062014 negative regulation of small molecule metabolic process 3/719 102/18722 0.756019051443174 0.999999985974598 SOD1/PGP/PARP1 3 GO:1902106 negative regulation of leukocyte differentiation 3/719 102/18722 0.756019051443174 0.999999985974598 HMGB1/PRDX2/NME1 3 GO:0007249 I-kappaB kinase/NF-kappaB signaling 9/719 281/18722 0.756081415547423 0.999999985974598 GAPDH/GSTP1/EEF1D/UBE2N/UBE2I/S100A13/ECT2/RHOC/FAIM 9 GO:0006699 bile acid biosynthetic process 1/719 36/18722 0.756134338703272 0.999999985974598 HSD17B10 1 GO:0009225 nucleotide-sugar metabolic process 1/719 36/18722 0.756134338703272 0.999999985974598 UGP2 1 GO:0010762 regulation of fibroblast migration 1/719 36/18722 0.756134338703272 0.999999985974598 ITGB1BP1 1 GO:0014741 negative regulation of muscle hypertrophy 1/719 36/18722 0.756134338703272 0.999999985974598 GLRX3 1 GO:0016180 snRNA processing 1/719 36/18722 0.756134338703272 0.999999985974598 EXOSC8 1 GO:0030224 monocyte differentiation 1/719 36/18722 0.756134338703272 0.999999985974598 PIR 1 GO:0042119 neutrophil activation 1/719 36/18722 0.756134338703272 0.999999985974598 ANXA3 1 GO:0051354 negative regulation of oxidoreductase activity 1/719 36/18722 0.756134338703272 0.999999985974598 CAV1 1 GO:0060251 regulation of glial cell proliferation 1/719 36/18722 0.756134338703272 0.999999985974598 IDH2 1 GO:0060338 regulation of type I interferon-mediated signaling pathway 1/719 36/18722 0.756134338703272 0.999999985974598 HSP90AB1 1 GO:0086010 membrane depolarization during action potential 1/719 36/18722 0.756134338703272 0.999999985974598 YWHAH 1 GO:0097009 energy homeostasis 1/719 36/18722 0.756134338703272 0.999999985974598 UBB 1 GO:0010565 regulation of cellular ketone metabolic process 4/719 133/18722 0.756308066124243 0.999999985974598 PARK7/COMT/CAV1/EIF6 4 GO:0046887 positive regulation of hormone secretion 4/719 133/18722 0.756308066124243 0.999999985974598 PHPT1/DYNLL1/MPC2/VAMP8 4 GO:0014013 regulation of gliogenesis 3/719 103/18722 0.761838965798497 0.999999985974598 IDH2/EZH2/RHEB 3 GO:0045639 positive regulation of myeloid cell differentiation 3/719 103/18722 0.761838965798497 0.999999985974598 HMGB2/HMGB1/PRMT1 3 GO:0090277 positive regulation of peptide hormone secretion 3/719 103/18722 0.761838965798497 0.999999985974598 PHPT1/DYNLL1/MPC2 3 GO:0033555 multicellular organismal response to stress 2/719 71/18722 0.76272487792273 0.999999985974598 VDAC1/COMT 2 GO:0061515 myeloid cell development 2/719 71/18722 0.76272487792273 0.999999985974598 RPS6/ANXA2 2 GO:0071230 cellular response to amino acid stimulus 2/719 71/18722 0.76272487792273 0.999999985974598 HNRNPD/DNMT1 2 GO:0070588 calcium ion transmembrane transport 10/719 312/18722 0.76335242363161 0.999999985974598 CALM2/GSTO1/CALM1/VDAC1/ANXA2/YWHAE/STOML2/C4orf3/BAX/MCUR1 10 GO:0016485 protein processing 7/719 225/18722 0.765429902951576 0.999999985974598 ENO1/BCL2L12/STOML2/BAG2/SEC11A/PARP1/METAP2 7 GO:0003016 respiratory system process 1/719 37/18722 0.765517802819313 0.999999985974598 ADH5 1 GO:0032885 regulation of polysaccharide biosynthetic process 1/719 37/18722 0.765517802819313 0.999999985974598 PPP1CA 1 GO:0043403 skeletal muscle tissue regeneration 1/719 37/18722 0.765517802819313 0.999999985974598 EZH2 1 GO:0060416 response to growth hormone 1/719 37/18722 0.765517802819313 0.999999985974598 CACYBP 1 GO:1900016 negative regulation of cytokine production involved in inflammatory response 1/719 37/18722 0.765517802819313 0.999999985974598 EZH2 1 GO:0048661 positive regulation of smooth muscle cell proliferation 3/719 104/18722 0.76754588737198 0.999999985974598 AKR1B1/PHB/DNMT1 3 GO:1901890 positive regulation of cell junction assembly 3/719 104/18722 0.76754588737198 0.999999985974598 S100A10/CAV1/ITGB1BP1 3 GO:0051924 regulation of calcium ion transport 8/719 255/18722 0.767608729966416 0.999999985974598 CALM2/GSTO1/CALM1/VDAC1/YWHAE/CAV1/C4orf3/BAX 8 GO:0032729 positive regulation of interferon-gamma production 2/719 72/18722 0.769484555555142 0.999999985974598 HSPD1/HRAS 2 GO:0042246 tissue regeneration 2/719 72/18722 0.769484555555142 0.999999985974598 CCNB1/EZH2 2 GO:0051057 positive regulation of small GTPase mediated signal transduction 2/719 72/18722 0.769484555555142 0.999999985974598 DYNLT1/HRAS 2 GO:1901880 negative regulation of protein depolymerization 2/719 72/18722 0.769484555555142 0.999999985974598 TPX2/CKAP2 2 GO:0098876 vesicle-mediated transport to the plasma membrane 4/719 136/18722 0.771472985964388 0.999999985974598 KRT18/VPS29/SNX3/NSG1 4 GO:0062207 regulation of pattern recognition receptor signaling pathway 3/719 105/18722 0.773140932563794 0.999999985974598 HMGB1/C1QBP/CAV1 3 GO:0006882 cellular zinc ion homeostasis 1/719 38/18722 0.774540692825892 0.999999985974598 MT2A 1 GO:0032941 secretion by tissue 1/719 38/18722 0.774540692825892 0.999999985974598 VAMP8 1 GO:0035886 vascular associated smooth muscle cell differentiation 1/719 38/18722 0.774540692825892 0.999999985974598 DNMT1 1 GO:0042491 inner ear auditory receptor cell differentiation 1/719 38/18722 0.774540692825892 0.999999985974598 SOD1 1 GO:0042596 fear response 1/719 38/18722 0.774540692825892 0.999999985974598 VDAC1 1 GO:0046329 negative regulation of JNK cascade 1/719 38/18722 0.774540692825892 0.999999985974598 GSTP1 1 GO:0048713 regulation of oligodendrocyte differentiation 1/719 38/18722 0.774540692825892 0.999999985974598 RHEB 1 GO:0051930 regulation of sensory perception of pain 1/719 38/18722 0.774540692825892 0.999999985974598 COMT 1 GO:0072538 T-helper 17 type immune response 1/719 38/18722 0.774540692825892 0.999999985974598 PHB 1 GO:0099622 cardiac muscle cell membrane repolarization 1/719 38/18722 0.774540692825892 0.999999985974598 YWHAE 1 GO:1903580 positive regulation of ATP metabolic process 1/719 38/18722 0.774540692825892 0.999999985974598 ENO1 1 GO:2000279 negative regulation of DNA biosynthetic process 1/719 38/18722 0.774540692825892 0.999999985974598 HNRNPA1 1 GO:0002637 regulation of immunoglobulin production 2/719 73/18722 0.776075903609899 0.999999985974598 PHB/PHB2 2 GO:0032732 positive regulation of interleukin-1 production 2/719 73/18722 0.776075903609899 0.999999985974598 HMGB1/S100A13 2 GO:0050848 regulation of calcium-mediated signaling 2/719 73/18722 0.776075903609899 0.999999985974598 CALM2/CALM1 2 GO:0051865 protein autoubiquitination 2/719 73/18722 0.776075903609899 0.999999985974598 UBE2T/RBX1 2 GO:0051937 catecholamine transport 2/719 73/18722 0.776075903609899 0.999999985974598 LY6E/PARK7 2 GO:0072089 stem cell proliferation 2/719 73/18722 0.776075903609899 0.999999985974598 HMGB2/CCNE1 2 GO:0050714 positive regulation of protein secretion 4/719 137/18722 0.776360380459551 0.999999985974598 PPIA/PHPT1/DYNLL1/MPC2 4 GO:0060048 cardiac muscle contraction 4/719 137/18722 0.776360380459551 0.999999985974598 CALM2/GSTO1/CALM1/CAV1 4 GO:2000241 regulation of reproductive process 5/719 168/18722 0.777601367207239 0.999999985974598 RAD51AP1/CDC20/AURKA/C1QBP/PHLDA2 5 GO:0002793 positive regulation of peptide secretion 3/719 106/18722 0.778625258622272 0.999999985974598 PHPT1/DYNLL1/MPC2 3 GO:0006766 vitamin metabolic process 3/719 106/18722 0.778625258622272 0.999999985974598 GSTO1/DHFR/VKORC1 3 GO:0042116 macrophage activation 3/719 106/18722 0.778625258622272 0.999999985974598 HMGB1/MIF/HSPD1 3 GO:1903707 negative regulation of hemopoiesis 3/719 106/18722 0.778625258622272 0.999999985974598 HMGB1/PRDX2/NME1 3 GO:1905477 positive regulation of protein localization to membrane 3/719 106/18722 0.778625258622272 0.999999985974598 PDCD5/HRAS/ITGB1BP1 3 GO:0010506 regulation of autophagy 10/719 317/18722 0.779929770302247 0.999999985974598 HMGB1/GAPDH/SLC25A5/EEF1A1/PARK7/VDAC1/CISD1/RHEB/PHB2/BNIP3 10 GO:0055076 transition metal ion homeostasis 4/719 138/18722 0.781164957384896 0.999999985974598 MT2A/SOD1/GLRX3/ISCU 4 GO:0030968 endoplasmic reticulum unfolded protein response 2/719 74/18722 0.782501860238649 0.999999985974598 CCND1/BAX 2 GO:0070972 protein localization to endoplasmic reticulum 2/719 74/18722 0.782501860238649 0.999999985974598 SRP14/SRP9 2 GO:1901568 fatty acid derivative metabolic process 2/719 74/18722 0.782501860238649 0.999999985974598 NUDT8/SLC25A1 2 GO:0006936 muscle contraction 11/719 347/18722 0.782900611589945 0.999999985974598 CALM2/GSTO1/ENO1/ALDOA/CALM1/SOD1/MYL6/HSBP1/CAV1/C12orf57/MKKS 11 GO:0051931 regulation of sensory perception 1/719 39/18722 0.783216845783405 0.999999985974598 COMT 1 GO:0071548 response to dexamethasone 1/719 39/18722 0.783216845783405 0.999999985974598 PCNA 1 GO:0090224 regulation of spindle organization 1/719 39/18722 0.783216845783405 0.999999985974598 TPX2 1 GO:1902742 apoptotic process involved in development 1/719 39/18722 0.783216845783405 0.999999985974598 BAX 1 GO:1903115 regulation of actin filament-based movement 1/719 39/18722 0.783216845783405 0.999999985974598 CAV1 1 GO:0071868 cellular response to monoamine stimulus 3/719 107/18722 0.784000060417748 0.999999985974598 GNAS/NSG1/ID1 3 GO:0071870 cellular response to catecholamine stimulus 3/719 107/18722 0.784000060417748 0.999999985974598 GNAS/NSG1/ID1 3 GO:0043087 regulation of GTPase activity 11/719 348/18722 0.785955122477183 0.999999985974598 STMN1/S100A10/SOD1/DYNLT1/ARL2/EZH2/ECT2/MKKS/PIN1/HRAS/ITGB1BP1 11 GO:0008088 axo-dendritic transport 2/719 75/18722 0.788765386456854 0.999999985974598 SOD1/HSBP1 2 GO:0033077 T cell differentiation in thymus 2/719 75/18722 0.788765386456854 0.999999985974598 RPS6/SOD1 2 GO:0034121 regulation of toll-like receptor signaling pathway 2/719 75/18722 0.788765386456854 0.999999985974598 HMGB1/CAV1 2 GO:0036465 synaptic vesicle recycling 2/719 75/18722 0.788765386456854 0.999999985974598 CALM1/ACTG1 2 GO:0048662 negative regulation of smooth muscle cell proliferation 2/719 75/18722 0.788765386456854 0.999999985974598 GSTP1/COMT 2 GO:0002832 negative regulation of response to biotic stimulus 3/719 108/18722 0.789266567343849 0.999999985974598 PRDX2/RPS19/C1QBP 3 GO:0034446 substrate adhesion-dependent cell spreading 3/719 108/18722 0.789266567343849 0.999999985974598 S100A10/C1QBP/ITGB1BP1 3 GO:0030833 regulation of actin filament polymerization 5/719 171/18722 0.790466259086282 0.999999985974598 PFN1/ARPC1A/ARPC5/ARPC5L/MKKS 5 GO:0030177 positive regulation of Wnt signaling pathway 4/719 140/18722 0.790528193785871 0.999999985974598 RPS12/CAV1/PIN1/RUVBL1 4 GO:0050768 negative regulation of neurogenesis 4/719 140/18722 0.790528193785871 0.999999985974598 YWHAH/DYNLT1/IDH2/ID1 4 GO:0030866 cortical actin cytoskeleton organization 1/719 40/18722 0.791559568466151 0.999999985974598 ECT2 1 GO:0043001 Golgi to plasma membrane protein transport 1/719 40/18722 0.791559568466151 0.999999985974598 KRT18 1 GO:0045022 early endosome to late endosome transport 1/719 40/18722 0.791559568466151 0.999999985974598 SNX3 1 GO:0045777 positive regulation of blood pressure 1/719 40/18722 0.791559568466151 0.999999985974598 ADH5 1 GO:0055069 zinc ion homeostasis 1/719 40/18722 0.791559568466151 0.999999985974598 MT2A 1 GO:0030900 forebrain development 12/719 379/18722 0.791844033458515 0.999999985974598 UQCRQ/RRM1/NME1/ANXA3/UBB/EZH2/C12orf57/ARPC5/ATIC/MKKS/BNIP3/BAX 12 GO:0043266 regulation of potassium ion transport 3/719 109/18722 0.794426040343499 0.999999985974598 YWHAE/CAV1/SUMO1 3 GO:0048515 spermatid differentiation 5/719 172/18722 0.7946234699649 0.999999985974598 HMGB2/DYNLL1/SLIRP/MKKS/BAX 5 GO:0014855 striated muscle cell proliferation 2/719 76/18722 0.794869460064761 0.999999985974598 CDK1/CCNB1 2 GO:0045685 regulation of glial cell differentiation 2/719 76/18722 0.794869460064761 0.999999985974598 CDK1/RHEB 2 GO:0034341 response to interferon-gamma 4/719 141/18722 0.79508818682931 0.999999985974598 GAPDH/RPL13A/ACTG1/HSP90AB1 4 GO:0035296 regulation of tube diameter 4/719 141/18722 0.79508818682931 0.999999985974598 SOD1/CAV1/MKKS/ITGB1BP1 4 GO:0097746 blood vessel diameter maintenance 4/719 141/18722 0.79508818682931 0.999999985974598 SOD1/CAV1/MKKS/ITGB1BP1 4 GO:0001819 positive regulation of cytokine production 15/719 467/18722 0.796017850358267 0.999999985974598 HMGB2/HMGB1/GAPDH/RPS3/MIF/SOD1/PARK7/HSPD1/HSP90AA1/S100A13/STOML2/PNP/PHB/DDT/HRAS 15 GO:0032869 cellular response to insulin stimulus 6/719 203/18722 0.79623847096569 0.999999985974598 GSTP1/NUCKS1/PKM/CDK4/PARP1/APRT 6 GO:0006694 steroid biosynthetic process 5/719 173/18722 0.798715838812204 0.999999985974598 SOD1/FDPS/HINT2/AKR1B1/HSD17B10 5 GO:0015833 peptide transport 8/719 264/18722 0.799217313156698 0.999999985974598 PHPT1/DYNLL1/PARK7/MPC2/UQCC2/ENY2/HADH/ENSA 8 GO:0032868 response to insulin 8/719 264/18722 0.799217313156698 0.999999985974598 GSTP1/NUCKS1/PKM/EIF6/HADH/CDK4/PARP1/APRT 8 GO:0006939 smooth muscle contraction 3/719 110/18722 0.799479769056847 0.999999985974598 SOD1/CAV1/MKKS 3 GO:0009063 cellular amino acid catabolic process 3/719 110/18722 0.799479769056847 0.999999985974598 GCSH/ECHS1/HSD17B10 3 GO:0035150 regulation of tube size 4/719 142/18722 0.799568026308351 0.999999985974598 SOD1/CAV1/MKKS/ITGB1BP1 4 GO:0097553 calcium ion transmembrane import into cytosol 4/719 142/18722 0.799568026308351 0.999999985974598 CALM2/GSTO1/CALM1/BAX 4 GO:0007099 centriole replication 1/719 41/18722 0.799581657657503 0.999999985974598 NPM1 1 GO:0010907 positive regulation of glucose metabolic process 1/719 41/18722 0.799581657657503 0.999999985974598 HMGB1 1 GO:0031062 positive regulation of histone methylation 1/719 41/18722 0.799581657657503 0.999999985974598 DNMT1 1 GO:0048286 lung alveolus development 1/719 41/18722 0.799581657657503 0.999999985974598 PTGES3 1 GO:0050691 regulation of defense response to virus by host 1/719 41/18722 0.799581657657503 0.999999985974598 HSP90AA1 1 GO:1901385 regulation of voltage-gated calcium channel activity 1/719 41/18722 0.799581657657503 0.999999985974598 CALM1 1 GO:1902622 regulation of neutrophil migration 1/719 41/18722 0.799581657657503 0.999999985974598 C1QBP 1 GO:2000008 regulation of protein localization to cell surface 1/719 41/18722 0.799581657657503 0.999999985974598 HSP90AB1 1 GO:0032418 lysosome localization 2/719 77/18722 0.800817070000353 0.999999985974598 S100A13/VAMP8 2 GO:0140056 organelle localization by membrane tethering 2/719 77/18722 0.800817070000353 0.999999985974598 CALM1/VAMP8 2 GO:0030522 intracellular receptor signaling pathway 8/719 265/18722 0.802521258189308 0.999999985974598 YWHAH/PTGES3/PARK7/C1QBP/EZH2/PHB/PARP1/PHB2 8 GO:0046879 hormone secretion 9/719 295/18722 0.80332391772507 0.999999985974598 PHPT1/DYNLL1/PARK7/MPC2/UQCC2/ENY2/VAMP8/HADH/ENSA 9 GO:0062013 positive regulation of small molecule metabolic process 4/719 143/18722 0.803968437977746 0.999999985974598 HMGB1/ENO1/PARK7/COMT 4 GO:0071867 response to monoamine 3/719 111/18722 0.804429069088263 0.999999985974598 GNAS/NSG1/ID1 3 GO:0071869 response to catecholamine 3/719 111/18722 0.804429069088263 0.999999985974598 GNAS/NSG1/ID1 3 GO:0042692 muscle cell differentiation 12/719 384/18722 0.805837357360499 0.999999985974598 CDK1/CSRP2/ACTG1/KRT19/CCNB1/YBX1/CACYBP/KRT8/MORF4L2/EZH2/DNMT1/PIN1 12 GO:0048738 cardiac muscle tissue development 7/719 236/18722 0.805980877253626 0.999999985974598 CDK1/CCNB1/CACYBP/LY6E/NDUFV2/PRMT1/PIN1 7 GO:0009064 glutamine family amino acid metabolic process 2/719 78/18722 0.806611211100159 0.999999985974598 GMPS/NIT2 2 GO:0032371 regulation of sterol transport 2/719 78/18722 0.806611211100159 0.999999985974598 ANXA2/CAV1 2 GO:0032374 regulation of cholesterol transport 2/719 78/18722 0.806611211100159 0.999999985974598 ANXA2/CAV1 2 GO:0010677 negative regulation of cellular carbohydrate metabolic process 1/719 42/18722 0.8072954196694 0.999999985974598 PGP 1 GO:0014003 oligodendrocyte development 1/719 42/18722 0.8072954196694 0.999999985974598 GSTP1 1 GO:0016601 Rac protein signal transduction 1/719 42/18722 0.8072954196694 0.999999985974598 DYNLT1 1 GO:0030890 positive regulation of B cell proliferation 1/719 42/18722 0.8072954196694 0.999999985974598 MIF 1 GO:0032691 negative regulation of interleukin-1 beta production 1/719 42/18722 0.8072954196694 0.999999985974598 GSTP1 1 GO:0033003 regulation of mast cell activation 1/719 42/18722 0.8072954196694 0.999999985974598 VAMP8 1 GO:0043507 positive regulation of JUN kinase activity 1/719 42/18722 0.8072954196694 0.999999985974598 RPS3 1 GO:0045687 positive regulation of glial cell differentiation 1/719 42/18722 0.8072954196694 0.999999985974598 RHEB 1 GO:0051602 response to electrical stimulus 1/719 42/18722 0.8072954196694 0.999999985974598 HNRNPD 1 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis 1/719 42/18722 0.8072954196694 0.999999985974598 ITGB1BP1 1 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic 1/719 42/18722 0.8072954196694 0.999999985974598 EXOSC8 1 GO:1903432 regulation of TORC1 signaling 1/719 42/18722 0.8072954196694 0.999999985974598 PIH1D1 1 GO:0008016 regulation of heart contraction 6/719 206/18722 0.807386052765221 0.999999985974598 CALM2/GSTO1/CALM1/YWHAE/CAV1/GLRX3 6 GO:0051235 maintenance of location 10/719 326/18722 0.80764223235631 0.999999985974598 CALM2/GSTO1/TXN/CALM1/PARK7/ARL2/CAV1/SKP1/MDFI/BAX 10 GO:0001676 long-chain fatty acid metabolic process 3/719 112/18722 0.809275279389512 0.999999985974598 GSTP1/PTGES3/GPX4 3 GO:0010633 negative regulation of epithelial cell migration 3/719 112/18722 0.809275279389512 0.999999985974598 HMGB1/CSNK2B/ITGB1BP1 3 GO:0046632 alpha-beta T cell differentiation 3/719 112/18722 0.809275279389512 0.999999985974598 HMGB1/RPL22/PNP 3 GO:0010634 positive regulation of epithelial cell migration 5/719 176/18722 0.810608461217432 0.999999985974598 HMGB1/PFN1/ANXA3/RAB25/ITGB1BP1 5 GO:0050728 negative regulation of inflammatory response 5/719 176/18722 0.810608461217432 0.999999985974598 GSTP1/PBK/RPS19/SOD1/PSMB4 5 GO:0050679 positive regulation of epithelial cell proliferation 6/719 207/18722 0.810994621588873 0.999999985974598 HMGB2/HMGB1/NME1/CCND1/HRAS/ID1 6 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 2/719 79/18722 0.812254879244993 0.999999985974598 S100A10/C1QBP 2 GO:0051961 negative regulation of nervous system development 4/719 145/18722 0.812533984105552 0.999999985974598 YWHAH/DYNLT1/IDH2/ID1 4 GO:0014014 negative regulation of gliogenesis 1/719 43/18722 0.814712689115744 0.999999985974598 IDH2 1 GO:0032365 intracellular lipid transport 1/719 43/18722 0.814712689115744 0.999999985974598 ANXA2 1 GO:0034142 toll-like receptor 4 signaling pathway 1/719 43/18722 0.814712689115744 0.999999985974598 HMGB1 1 GO:0034661 ncRNA catabolic process 1/719 43/18722 0.814712689115744 0.999999985974598 EXOSC8 1 GO:0036230 granulocyte activation 1/719 43/18722 0.814712689115744 0.999999985974598 ANXA3 1 GO:0042181 ketone biosynthetic process 1/719 43/18722 0.814712689115744 0.999999985974598 TPI1 1 GO:0045494 photoreceptor cell maintenance 1/719 43/18722 0.814712689115744 0.999999985974598 MKKS 1 GO:0045776 negative regulation of blood pressure 1/719 43/18722 0.814712689115744 0.999999985974598 MKKS 1 GO:0045981 positive regulation of nucleotide metabolic process 1/719 43/18722 0.814712689115744 0.999999985974598 ENO1 1 GO:0046636 negative regulation of alpha-beta T cell activation 1/719 43/18722 0.814712689115744 0.999999985974598 HMGB1 1 GO:0098927 vesicle-mediated transport between endosomal compartments 1/719 43/18722 0.814712689115744 0.999999985974598 SNX3 1 GO:0120178 steroid hormone biosynthetic process 1/719 43/18722 0.814712689115744 0.999999985974598 AKR1B1 1 GO:1900544 positive regulation of purine nucleotide metabolic process 1/719 43/18722 0.814712689115744 0.999999985974598 ENO1 1 GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation 1/719 43/18722 0.814712689115744 0.999999985974598 GSTP1 1 GO:0007422 peripheral nervous system development 2/719 80/18722 0.817751066868848 0.999999985974598 CDK1/SOD1 2 GO:0071229 cellular response to acid chemical 2/719 80/18722 0.817751066868848 0.999999985974598 HNRNPD/DNMT1 2 GO:0046660 female sex differentiation 3/719 114/18722 0.818663888434456 0.999999985974598 SOD1/UBB/BAX 3 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 3/719 114/18722 0.818663888434456 0.999999985974598 HSP90AB1/CSNK2B/PARP1 3 GO:0006775 fat-soluble vitamin metabolic process 1/719 44/18722 0.821844846968186 0.999999985974598 VKORC1 1 GO:0032620 interleukin-17 production 1/719 44/18722 0.821844846968186 0.999999985974598 PHB 1 GO:0032660 regulation of interleukin-17 production 1/719 44/18722 0.821844846968186 0.999999985974598 PHB 1 GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT 1/719 44/18722 0.821844846968186 0.999999985974598 AKR1B1 1 GO:0048066 developmental pigmentation 1/719 44/18722 0.821844846968186 0.999999985974598 BAX 1 GO:0048806 genitalia development 1/719 44/18722 0.821844846968186 0.999999985974598 BAX 1 GO:0051150 regulation of smooth muscle cell differentiation 1/719 44/18722 0.821844846968186 0.999999985974598 DNMT1 1 GO:0060324 face development 1/719 44/18722 0.821844846968186 0.999999985974598 MKKS 1 GO:1903573 negative regulation of response to endoplasmic reticulum stress 1/719 44/18722 0.821844846968186 0.999999985974598 PARK7 1 GO:0060047 heart contraction 7/719 241/18722 0.822543173684297 0.999999985974598 CALM2/GSTO1/CALM1/SOD1/YWHAE/CAV1/GLRX3 7 GO:0001523 retinoid metabolic process 2/719 81/18722 0.823102758810284 0.999999985974598 AKR1B1/ADH5 2 GO:0001960 negative regulation of cytokine-mediated signaling pathway 2/719 81/18722 0.823102758810284 0.999999985974598 GSTP1/CAV1 2 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 2/719 81/18722 0.823102758810284 0.999999985974598 CAV1/PIN1 2 GO:0051149 positive regulation of muscle cell differentiation 2/719 81/18722 0.823102758810284 0.999999985974598 MORF4L2/PIN1 2 GO:0044272 sulfur compound biosynthetic process 4/719 148/18722 0.824805867176321 0.999999985974598 GSTP1/MPC2/ADI1/SLC25A1 4 GO:0010721 negative regulation of cell development 5/719 180/18722 0.825586554437625 0.999999985974598 YWHAH/DYNLT1/IDH2/ID1/ITGB1BP1 5 GO:0006720 isoprenoid metabolic process 3/719 116/18722 0.827656682352307 0.999999985974598 FDPS/AKR1B1/ADH5 3 GO:0035967 cellular response to topologically incorrect protein 3/719 116/18722 0.827656682352307 0.999999985974598 HSPD1/CCND1/BAX 3 GO:0002312 B cell activation involved in immune response 2/719 82/18722 0.828312928486685 0.999999985974598 UNG/HSPD1 2 GO:0016575 histone deacetylation 2/719 82/18722 0.828312928486685 0.999999985974598 MORF4L2/PHB 2 GO:0043242 negative regulation of protein-containing complex disassembly 2/719 82/18722 0.828312928486685 0.999999985974598 TPX2/CKAP2 2 GO:0060395 SMAD protein signal transduction 2/719 82/18722 0.828312928486685 0.999999985974598 SUB1/PARP1 2 GO:0003254 regulation of membrane depolarization 1/719 45/18722 0.828702837921708 0.999999985974598 PARP1 1 GO:0006903 vesicle targeting 1/719 45/18722 0.828702837921708 0.999999985974598 AP1M2 1 GO:0010824 regulation of centrosome duplication 1/719 45/18722 0.828702837921708 0.999999985974598 NPM1 1 GO:0035987 endodermal cell differentiation 1/719 45/18722 0.828702837921708 0.999999985974598 HSBP1 1 GO:0044088 regulation of vacuole organization 1/719 45/18722 0.828702837921708 0.999999985974598 ANXA2 1 GO:0045910 negative regulation of DNA recombination 1/719 45/18722 0.828702837921708 0.999999985974598 RMI2 1 GO:0060119 inner ear receptor cell development 1/719 45/18722 0.828702837921708 0.999999985974598 SOD1 1 GO:0071354 cellular response to interleukin-6 1/719 45/18722 0.828702837921708 0.999999985974598 PHB 1 GO:0098534 centriole assembly 1/719 45/18722 0.828702837921708 0.999999985974598 NPM1 1 GO:1901985 positive regulation of protein acetylation 1/719 45/18722 0.828702837921708 0.999999985974598 PIH1D1 1 GO:1904646 cellular response to amyloid-beta 1/719 45/18722 0.828702837921708 0.999999985974598 PARP1 1 GO:0032640 tumor necrosis factor production 5/719 181/18722 0.829177658902201 0.999999985974598 HMGB1/GSTP1/MIF/HSPD1/DDT 5 GO:0032680 regulation of tumor necrosis factor production 5/719 181/18722 0.829177658902201 0.999999985974598 HMGB1/GSTP1/MIF/HSPD1/DDT 5 GO:1905952 regulation of lipid localization 5/719 181/18722 0.829177658902201 0.999999985974598 DBI/ANXA2/PRELID1/TRIAP1/CAV1 5 GO:0001959 regulation of cytokine-mediated signaling pathway 4/719 150/18722 0.83261235067031 0.999999985974598 GSTP1/HSP90AB1/CD24/CAV1 4 GO:0043270 positive regulation of ion transport 8/719 275/18722 0.833332665239201 0.999999985974598 CALM2/GSTO1/CALM1/NDUFA4/COX17/CAV1/VAMP8/BAX 8 GO:0001974 blood vessel remodeling 1/719 46/18722 0.835297187096324 0.999999985974598 BAX 1 GO:0031018 endocrine pancreas development 1/719 46/18722 0.835297187096324 0.999999985974598 RHEB 1 GO:0032924 activin receptor signaling pathway 1/719 46/18722 0.835297187096324 0.999999985974598 CSNK2B 1 GO:0043300 regulation of leukocyte degranulation 1/719 46/18722 0.835297187096324 0.999999985974598 VAMP8 1 GO:0055010 ventricular cardiac muscle tissue morphogenesis 1/719 46/18722 0.835297187096324 0.999999985974598 LY6E 1 GO:1900271 regulation of long-term synaptic potentiation 1/719 46/18722 0.835297187096324 0.999999985974598 NSG1 1 GO:2000107 negative regulation of leukocyte apoptotic process 1/719 46/18722 0.835297187096324 0.999999985974598 AURKB 1 GO:0009914 hormone transport 9/719 306/18722 0.83538742663379 0.999999985974598 PHPT1/DYNLL1/PARK7/MPC2/UQCC2/ENY2/VAMP8/HADH/ENSA 9 GO:0022612 gland morphogenesis 3/719 118/18722 0.836264971845832 0.999999985974598 CAV1/PHB2/BAX 3 GO:1904064 positive regulation of cation transmembrane transport 4/719 151/18722 0.83640569142141 0.999999985974598 CALM2/GSTO1/CALM1/BAX 4 GO:0031668 cellular response to extracellular stimulus 7/719 246/18722 0.837980231502235 0.999999985974598 GSTP1/HNRNPA1/COMT/DCTPP1/NUDT1/NUDT15/TXN2 7 GO:0015844 monoamine transport 2/719 84/18722 0.838320516765622 0.999999985974598 LY6E/PARK7 2 GO:0042310 vasoconstriction 2/719 84/18722 0.838320516765622 0.999999985974598 CAV1/MKKS 2 GO:0045445 myoblast differentiation 2/719 84/18722 0.838320516765622 0.999999985974598 DTYMK/ID3 2 GO:2001257 regulation of cation channel activity 5/719 184/18722 0.839591706777268 0.999999985974598 CALM2/GSTO1/CALM1/CAV1/SUMO1 5 GO:0050870 positive regulation of T cell activation 6/719 216/18722 0.841128067798469 0.999999985974598 HMGB1/RPS3/CD24/HSPD1/CAV1/PNP 6 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 1/719 47/18722 0.841638016100272 0.999999985974598 GSTP1 1 GO:0014911 positive regulation of smooth muscle cell migration 1/719 47/18722 0.841638016100272 0.999999985974598 S100A11 1 GO:0035315 hair cell differentiation 1/719 47/18722 0.841638016100272 0.999999985974598 SOD1 1 GO:0035850 epithelial cell differentiation involved in kidney development 1/719 47/18722 0.841638016100272 0.999999985974598 CD24 1 GO:0045601 regulation of endothelial cell differentiation 1/719 47/18722 0.841638016100272 0.999999985974598 ID1 1 GO:0045747 positive regulation of Notch signaling pathway 1/719 47/18722 0.841638016100272 0.999999985974598 ITGB1BP1 1 GO:0061001 regulation of dendritic spine morphogenesis 1/719 47/18722 0.841638016100272 0.999999985974598 CFL1 1 GO:0090279 regulation of calcium ion import 1/719 47/18722 0.841638016100272 0.999999985974598 VDAC1 1 GO:0097028 dendritic cell differentiation 1/719 47/18722 0.841638016100272 0.999999985974598 HMGB1 1 GO:0101023 vascular endothelial cell proliferation 1/719 47/18722 0.841638016100272 0.999999985974598 HMGB1 1 GO:1900744 regulation of p38MAPK cascade 1/719 47/18722 0.841638016100272 0.999999985974598 PRMT1 1 GO:1905562 regulation of vascular endothelial cell proliferation 1/719 47/18722 0.841638016100272 0.999999985974598 HMGB1 1 GO:0007281 germ cell development 8/719 278/18722 0.841805719255585 0.999999985974598 HMGB2/RPS6/CCNB1/DYNLL1/AURKA/SLIRP/MKKS/BAX 8 GO:0001656 metanephros development 2/719 85/18722 0.84312379481969 0.999999985974598 AKR1B1/ID3 2 GO:0002709 regulation of T cell mediated immunity 2/719 85/18722 0.84312379481969 0.999999985974598 HMGB1/HSPD1 2 GO:0060021 roof of mouth development 2/719 85/18722 0.84312379481969 0.999999985974598 ANP32B/SUMO1 2 GO:0097194 execution phase of apoptosis 2/719 85/18722 0.84312379481969 0.999999985974598 TOP2A/BAX 2 GO:0120254 olefinic compound metabolic process 4/719 153/18722 0.843776903211994 0.999999985974598 GSTP1/PTGES3/GPX4/AKR1B1 4 GO:0070374 positive regulation of ERK1 and ERK2 cascade 6/719 217/18722 0.84422310802295 0.999999985974598 HMGB1/MIF/PHB/DDT/PHB2/HRAS 6 GO:0048593 camera-type eye morphogenesis 3/719 120/18722 0.844500227126237 0.999999985974598 HMGN1/C12orf57/BAX 3 GO:0071706 tumor necrosis factor superfamily cytokine production 5/719 186/18722 0.846240864689619 0.999999985974598 HMGB1/GSTP1/MIF/HSPD1/DDT 5 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 5/719 186/18722 0.846240864689619 0.999999985974598 HMGB1/GSTP1/MIF/HSPD1/DDT 5 GO:0045926 negative regulation of growth 7/719 249/18722 0.846718131945234 0.999999985974598 MT2A/ENO1/RBBP7/CDKN2A/NDUFA13/PHB/NDUFS3 7 GO:0045088 regulation of innate immune response 6/719 218/18722 0.847269079632165 0.999999985974598 HMGB2/HMGB1/RPS19/HSP90AB1/HSP90AA1/XRCC6 6 GO:0006111 regulation of gluconeogenesis 1/719 48/18722 0.847735058479062 0.999999985974598 PGP 1 GO:0033628 regulation of cell adhesion mediated by integrin 1/719 48/18722 0.847735058479062 0.999999985974598 ITGB1BP1 1 GO:0042149 cellular response to glucose starvation 1/719 48/18722 0.847735058479062 0.999999985974598 HNRNPA1 1 GO:0045912 negative regulation of carbohydrate metabolic process 1/719 48/18722 0.847735058479062 0.999999985974598 PGP 1 GO:1902003 regulation of amyloid-beta formation 1/719 48/18722 0.847735058479062 0.999999985974598 PIN1 1 GO:0046928 regulation of neurotransmitter secretion 2/719 86/18722 0.847797263835469 0.999999985974598 CALM1/PNKD 2 GO:0060761 negative regulation of response to cytokine stimulus 2/719 86/18722 0.847797263835469 0.999999985974598 GSTP1/CAV1 2 GO:0002224 toll-like receptor signaling pathway 3/719 121/18722 0.848481580374405 0.999999985974598 HMGB1/HSPD1/CAV1 3 GO:0034764 positive regulation of transmembrane transport 6/719 219/18722 0.850266429789194 0.999999985974598 CALM2/GSTO1/CALM1/NDUFA4/COX17/BAX 6 GO:0003015 heart process 7/719 251/18722 0.852330437247722 0.999999985974598 CALM2/GSTO1/CALM1/SOD1/YWHAE/CAV1/GLRX3 7 GO:0016101 diterpenoid metabolic process 2/719 87/18722 0.85234379278719 0.999999985974598 AKR1B1/ADH5 2 GO:1901606 alpha-amino acid catabolic process 2/719 87/18722 0.85234379278719 0.999999985974598 GCSH/HSD17B10 2 GO:0097529 myeloid leukocyte migration 6/719 220/18722 0.853215612110546 0.999999985974598 HMGB1/PPIA/RPS19/MIF/C1QBP/DDT 6 GO:0002762 negative regulation of myeloid leukocyte differentiation 1/719 49/18722 0.853597674573823 0.999999985974598 NME1 1 GO:0008206 bile acid metabolic process 1/719 49/18722 0.853597674573823 0.999999985974598 HSD17B10 1 GO:0009395 phospholipid catabolic process 1/719 49/18722 0.853597674573823 0.999999985974598 PRDX6 1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 1/719 49/18722 0.853597674573823 0.999999985974598 CSNK2B 1 GO:0030195 negative regulation of blood coagulation 1/719 49/18722 0.853597674573823 0.999999985974598 ANXA2 1 GO:0030225 macrophage differentiation 1/719 49/18722 0.853597674573823 0.999999985974598 PARP1 1 GO:0032692 negative regulation of interleukin-1 production 1/719 49/18722 0.853597674573823 0.999999985974598 GSTP1 1 GO:0042304 regulation of fatty acid biosynthetic process 1/719 49/18722 0.853597674573823 0.999999985974598 EIF6 1 GO:0043330 response to exogenous dsRNA 1/719 49/18722 0.853597674573823 0.999999985974598 CAV1 1 GO:0046580 negative regulation of Ras protein signal transduction 1/719 49/18722 0.853597674573823 0.999999985974598 STMN1 1 GO:0048168 regulation of neuronal synaptic plasticity 1/719 49/18722 0.853597674573823 0.999999985974598 HRAS 1 GO:0050832 defense response to fungus 1/719 49/18722 0.853597674573823 0.999999985974598 GAPDH 1 GO:0070741 response to interleukin-6 1/719 49/18722 0.853597674573823 0.999999985974598 PHB 1 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 1/719 49/18722 0.853597674573823 0.999999985974598 DNMT1 1 GO:1904894 positive regulation of receptor signaling pathway via STAT 1/719 49/18722 0.853597674573823 0.999999985974598 AKR1B1 1 GO:0035051 cardiocyte differentiation 4/719 156/18722 0.854308315743405 0.999999985974598 CDK1/CCNB1/CACYBP/PIN1 4 GO:0046631 alpha-beta T cell activation 4/719 156/18722 0.854308315743405 0.999999985974598 HMGB1/RPL22/STOML2/PNP 4 GO:0030098 lymphocyte differentiation 11/719 374/18722 0.854804706135346 0.999999985974598 HMGB1/PRDX2/SLC25A5/RPS6/RPL22/SOD1/PRELID1/XRCC6/EZH2/PNP/BAX 11 GO:0010810 regulation of cell-substrate adhesion 6/719 221/18722 0.856117086231307 0.999999985974598 S100A10/ACTG1/ARL2/C1QBP/CDKN2A/ITGB1BP1 6 GO:0001843 neural tube closure 2/719 88/18722 0.856766222074947 0.999999985974598 PFN1/RPS7 2 GO:0002253 activation of immune response 11/719 375/18722 0.857061027273767 0.999999985974598 HMGB1/RPS3/PHPT1/UBE2N/C1QBP/HSP90AA1/XRCC6/STOML2/PHB/HRAS/BAX 11 GO:0007632 visual behavior 1/719 50/18722 0.859234865811514 0.999999985974598 DYNLRB1 1 GO:0008089 anterograde axonal transport 1/719 50/18722 0.859234865811514 0.999999985974598 SOD1 1 GO:0010665 regulation of cardiac muscle cell apoptotic process 1/719 50/18722 0.859234865811514 0.999999985974598 BNIP3 1 GO:0015872 dopamine transport 1/719 50/18722 0.859234865811514 0.999999985974598 PARK7 1 GO:0018023 peptidyl-lysine trimethylation 1/719 50/18722 0.859234865811514 0.999999985974598 PIH1D1 1 GO:0038202 TORC1 signaling 1/719 50/18722 0.859234865811514 0.999999985974598 PIH1D1 1 GO:0042572 retinol metabolic process 1/719 50/18722 0.859234865811514 0.999999985974598 AKR1B1 1 GO:0046638 positive regulation of alpha-beta T cell differentiation 1/719 50/18722 0.859234865811514 0.999999985974598 PNP 1 GO:0050873 brown fat cell differentiation 1/719 50/18722 0.859234865811514 0.999999985974598 BNIP3 1 GO:0060337 type I interferon signaling pathway 1/719 50/18722 0.859234865811514 0.999999985974598 HSP90AB1 1 GO:0060688 regulation of morphogenesis of a branching structure 1/719 50/18722 0.859234865811514 0.999999985974598 PHB2 1 GO:0090102 cochlea development 1/719 50/18722 0.859234865811514 0.999999985974598 CCNA2 1 GO:1900047 negative regulation of hemostasis 1/719 50/18722 0.859234865811514 0.999999985974598 ANXA2 1 GO:1901570 fatty acid derivative biosynthetic process 1/719 50/18722 0.859234865811514 0.999999985974598 SLC25A1 1 GO:1902930 regulation of alcohol biosynthetic process 1/719 50/18722 0.859234865811514 0.999999985974598 SOD1 1 GO:0001909 leukocyte mediated cytotoxicity 3/719 124/18722 0.8598979656736 0.999999985974598 TUBB/TUBB4B/PRDX1 3 GO:0046330 positive regulation of JNK cascade 2/719 89/18722 0.861067361487817 0.999999985974598 HMGB1/HRAS 2 GO:0060606 tube closure 2/719 89/18722 0.861067361487817 0.999999985974598 PFN1/RPS7 2 GO:0002274 myeloid leukocyte activation 6/719 223/18722 0.861778775968022 0.999999985974598 HMGB1/MIF/ANXA3/HSPD1/S100A13/VAMP8 6 GO:0060294 cilium movement involved in cell motility 3/719 125/18722 0.863532378859981 0.999999985974598 SLIRP/CFAP20/MKKS 3 GO:0009948 anterior/posterior axis specification 1/719 51/18722 0.8646552884487 0.999999985974598 AURKA 1 GO:0010656 negative regulation of muscle cell apoptotic process 1/719 51/18722 0.8646552884487 0.999999985974598 DNMT1 1 GO:0010874 regulation of cholesterol efflux 1/719 51/18722 0.8646552884487 0.999999985974598 CAV1 1 GO:0014009 glial cell proliferation 1/719 51/18722 0.8646552884487 0.999999985974598 IDH2 1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 1/719 51/18722 0.8646552884487 0.999999985974598 GSTP1 1 GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 1/719 51/18722 0.8646552884487 0.999999985974598 HMGB1 1 GO:0045661 regulation of myoblast differentiation 1/719 51/18722 0.8646552884487 0.999999985974598 ID3 1 GO:0045668 negative regulation of osteoblast differentiation 1/719 51/18722 0.8646552884487 0.999999985974598 ID3 1 GO:0050982 detection of mechanical stimulus 1/719 51/18722 0.8646552884487 0.999999985974598 MKKS 1 GO:0071622 regulation of granulocyte chemotaxis 1/719 51/18722 0.8646552884487 0.999999985974598 C1QBP 1 GO:1903307 positive regulation of regulated secretory pathway 1/719 51/18722 0.8646552884487 0.999999985974598 VAMP8 1 GO:0045638 negative regulation of myeloid cell differentiation 2/719 90/18722 0.865249988365087 0.999999985974598 NME1/PRMT1 2 GO:0061097 regulation of protein tyrosine kinase activity 2/719 90/18722 0.865249988365087 0.999999985974598 CD24/CAV1 2 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 2/719 90/18722 0.865249988365087 0.999999985974598 GSTP1/DNMT1 2 GO:0031929 TOR signaling 3/719 126/18722 0.867083685007887 0.999999985974598 RPS6/PIH1D1/RHEB 3 GO:0032874 positive regulation of stress-activated MAPK cascade 3/719 126/18722 0.867083685007887 0.999999985974598 HMGB1/PRMT1/HRAS 3 GO:0030217 T cell differentiation 7/719 257/18722 0.868176290723707 0.999999985974598 HMGB1/PRDX2/RPS6/RPL22/SOD1/PRELID1/PNP 7 GO:0002065 columnar/cuboidal epithelial cell differentiation 2/719 91/18722 0.869316845943427 0.999999985974598 TYMS/RHEB 2 GO:0042147 retrograde transport, endosome to Golgi 2/719 91/18722 0.869316845943427 0.999999985974598 VPS29/SNX3 2 GO:1990874 vascular associated smooth muscle cell proliferation 2/719 91/18722 0.869316845943427 0.999999985974598 GSTP1/DNMT1 2 GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 1/719 52/18722 0.86986726678973 0.999999985974598 COPE 1 GO:0007129 homologous chromosome pairing at meiosis 1/719 52/18722 0.86986726678973 0.999999985974598 CCNE1 1 GO:0010662 regulation of striated muscle cell apoptotic process 1/719 52/18722 0.86986726678973 0.999999985974598 BNIP3 1 GO:0010718 positive regulation of epithelial to mesenchymal transition 1/719 52/18722 0.86986726678973 0.999999985974598 EZH2 1 GO:0021545 cranial nerve development 1/719 52/18722 0.86986726678973 0.999999985974598 RPL24 1 GO:0031103 axon regeneration 1/719 52/18722 0.86986726678973 0.999999985974598 DHFR 1 GO:0035176 social behavior 1/719 52/18722 0.86986726678973 0.999999985974598 MKKS 1 GO:0035196 production of miRNAs involved in gene silencing by miRNA 1/719 52/18722 0.86986726678973 0.999999985974598 HNRNPA2B1 1 GO:0043277 apoptotic cell clearance 1/719 52/18722 0.86986726678973 0.999999985974598 HMGB1 1 GO:0048260 positive regulation of receptor-mediated endocytosis 1/719 52/18722 0.86986726678973 0.999999985974598 ANXA2 1 GO:0071357 cellular response to type I interferon 1/719 52/18722 0.86986726678973 0.999999985974598 HSP90AB1 1 GO:0007018 microtubule-based movement 11/719 382/18722 0.872091293099172 0.999999985974598 SOD1/DYNLT1/SLIRP/UBB/HSBP1/HSPB11/DYNLRB1/CFAP20/MKKS/UXT/SSNA1 11 GO:0046777 protein autophosphorylation 6/719 227/18722 0.87255045186945 0.999999985974598 CALM2/AURKB/CALM1/AURKA/VRK1/CAV1 6 GO:0006497 protein lipidation 2/719 92/18722 0.873270641878465 0.999999985974598 DBI/ZDHHC12 2 GO:0070509 calcium ion import 2/719 92/18722 0.873270641878465 0.999999985974598 VDAC1/MCUR1 2 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 3/719 128/18722 0.873942751709817 0.999999985974598 HSP90AB1/CAV1/PIN1 3 GO:0032612 interleukin-1 production 3/719 128/18722 0.873942751709817 0.999999985974598 HMGB1/GSTP1/S100A13 3 GO:0032652 regulation of interleukin-1 production 3/719 128/18722 0.873942751709817 0.999999985974598 HMGB1/GSTP1/S100A13 3 GO:0033865 nucleoside bisphosphate metabolic process 3/719 128/18722 0.873942751709817 0.999999985974598 MPC2/NUDT8/SLC25A1 3 GO:0033875 ribonucleoside bisphosphate metabolic process 3/719 128/18722 0.873942751709817 0.999999985974598 MPC2/NUDT8/SLC25A1 3 GO:0034032 purine nucleoside bisphosphate metabolic process 3/719 128/18722 0.873942751709817 0.999999985974598 MPC2/NUDT8/SLC25A1 3 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 3/719 128/18722 0.873942751709817 0.999999985974598 HMGB1/PRMT1/HRAS 3 GO:0008347 glial cell migration 1/719 53/18722 0.874878805899435 0.999999985974598 IDH2 1 GO:0033059 cellular pigmentation 1/719 53/18722 0.874878805899435 0.999999985974598 MKKS 1 GO:0034381 plasma lipoprotein particle clearance 1/719 53/18722 0.874878805899435 0.999999985974598 ANXA2 1 GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 1/719 53/18722 0.874878805899435 0.999999985974598 STMN1 1 GO:0045806 negative regulation of endocytosis 1/719 53/18722 0.874878805899435 0.999999985974598 CAV1 1 GO:0071320 cellular response to cAMP 1/719 53/18722 0.874878805899435 0.999999985974598 APEX1 1 GO:1990090 cellular response to nerve growth factor stimulus 1/719 53/18722 0.874878805899435 0.999999985974598 ID1 1 GO:0010976 positive regulation of neuron projection development 4/719 163/18722 0.87655636728634 0.999999985974598 NME1/DYNLT1/EZH2/SNX3 4 GO:0019217 regulation of fatty acid metabolic process 2/719 93/18722 0.877114046929847 0.999999985974598 CAV1/EIF6 2 GO:0032088 negative regulation of NF-kappaB transcription factor activity 2/719 93/18722 0.877114046929847 0.999999985974598 PRDX2/CDKN2A 2 GO:0032755 positive regulation of interleukin-6 production 2/719 93/18722 0.877114046929847 0.999999985974598 HMGB1/HSPD1 2 GO:0097306 cellular response to alcohol 2/719 93/18722 0.877114046929847 0.999999985974598 RAD51/CDK4 2 GO:0001649 osteoblast differentiation 6/719 229/18722 0.877668199739342 0.999999985974598 RPS15/HSPE1/ALYREF/PHB/FBL/ID3 6 GO:0071356 cellular response to tumor necrosis factor 6/719 229/18722 0.877668199739342 0.999999985974598 GSTP1/RPS3/KRT8/KRT18/EIF5A/TXNDC17 6 GO:0001706 endoderm formation 1/719 54/18722 0.879697603829603 0.999999985974598 HSBP1 1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1/719 54/18722 0.879697603829603 0.999999985974598 ITGB1BP1 1 GO:0010659 cardiac muscle cell apoptotic process 1/719 54/18722 0.879697603829603 0.999999985974598 BNIP3 1 GO:0014888 striated muscle adaptation 1/719 54/18722 0.879697603829603 0.999999985974598 EZH2 1 GO:0030834 regulation of actin filament depolymerization 1/719 54/18722 0.879697603829603 0.999999985974598 DSTN 1 GO:0031050 dsRNA processing 1/719 54/18722 0.879697603829603 0.999999985974598 HNRNPA2B1 1 GO:0043647 inositol phosphate metabolic process 1/719 54/18722 0.879697603829603 0.999999985974598 IMPA2 1 GO:0051703 biological process involved in intraspecies interaction between organisms 1/719 54/18722 0.879697603829603 0.999999985974598 MKKS 1 GO:0070918 production of small RNA involved in gene silencing by RNA 1/719 54/18722 0.879697603829603 0.999999985974598 HNRNPA2B1 1 GO:0086002 cardiac muscle cell action potential involved in contraction 1/719 54/18722 0.879697603829603 0.999999985974598 CAV1 1 GO:2000179 positive regulation of neural precursor cell proliferation 1/719 54/18722 0.879697603829603 0.999999985974598 NAP1L1 1 GO:2000300 regulation of synaptic vesicle exocytosis 1/719 54/18722 0.879697603829603 0.999999985974598 CALM1 1 GO:0030595 leukocyte chemotaxis 6/719 230/18722 0.880161774800956 0.999999985974598 HMGB1/PPIA/RPS19/MIF/C1QBP/DDT 6 GO:0002690 positive regulation of leukocyte chemotaxis 2/719 94/18722 0.880849693799427 0.999999985974598 HMGB1/C1QBP 2 GO:0014020 primary neural tube formation 2/719 94/18722 0.880849693799427 0.999999985974598 PFN1/RPS7 2 GO:0030316 osteoclast differentiation 2/719 94/18722 0.880849693799427 0.999999985974598 ANXA2/GLO1 2 GO:0007179 transforming growth factor beta receptor signaling pathway 5/719 198/18722 0.881498595124545 0.999999985974598 HSP90AB1/CAV1/PARP1/PIN1/ID1 5 GO:0007286 spermatid development 4/719 165/18722 0.882348045864309 0.999999985974598 HMGB2/DYNLL1/SLIRP/MKKS 4 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 3/719 131/18722 0.883643989514122 0.999999985974598 HSP90AB1/CAV1/PIN1 3 GO:0002067 glandular epithelial cell differentiation 1/719 55/18722 0.884331063377841 0.999999985974598 RHEB 1 GO:0003229 ventricular cardiac muscle tissue development 1/719 55/18722 0.884331063377841 0.999999985974598 LY6E 1 GO:0010676 positive regulation of cellular carbohydrate metabolic process 1/719 55/18722 0.884331063377841 0.999999985974598 HMGB1 1 GO:0038066 p38MAPK cascade 1/719 55/18722 0.884331063377841 0.999999985974598 PRMT1 1 GO:0051898 negative regulation of protein kinase B signaling 1/719 55/18722 0.884331063377841 0.999999985974598 PHLDA3 1 GO:0061098 positive regulation of protein tyrosine kinase activity 1/719 55/18722 0.884331063377841 0.999999985974598 CD24 1 GO:1902991 regulation of amyloid precursor protein catabolic process 1/719 55/18722 0.884331063377841 0.999999985974598 PIN1 1 GO:0042982 amyloid precursor protein metabolic process 2/719 95/18722 0.8844801761128 0.999999985974598 NSG1/PIN1 2 GO:0002831 regulation of response to biotic stimulus 9/719 327/18722 0.885151642316242 0.999999985974598 HMGB2/HMGB1/PRDX2/RPS19/HSP90AB1/HSPD1/C1QBP/HSP90AA1/XRCC6 9 GO:0043410 positive regulation of MAPK cascade 14/719 480/18722 0.886059158292241 0.999999985974598 HMGB1/PPIA/PRDX2/RPS3/MIF/SOD1/CD24/EZH2/PHB/DDT/NENF/PRMT1/PHB2/HRAS 14 GO:0045216 cell-cell junction organization 5/719 200/18722 0.886649963792568 0.999999985974598 ACTG1/ARL2/CAV1/ECT2/RHOC 5 GO:0035264 multicellular organism growth 3/719 132/18722 0.886726786272694 0.999999985974598 SOD1/CDK4/MKKS 3 GO:0032102 negative regulation of response to external stimulus 12/719 420/18722 0.886771253303064 0.999999985974598 PRDX2/GSTP1/PBK/RPS19/MIF/SOD1/ANXA2/C1QBP/DDT/NENF/MKKS/PSMB4 12 GO:0051607 defense response to virus 7/719 265/18722 0.887103553206091 0.999999985974598 C1QBP/HSP90AA1/POLR3K/VAMP8/PHB/PHB2/BNIP3 7 GO:0140546 defense response to symbiont 7/719 265/18722 0.887103553206091 0.999999985974598 C1QBP/HSP90AA1/POLR3K/VAMP8/PHB/PHB2/BNIP3 7 GO:0009306 protein secretion 10/719 359/18722 0.887191184764331 0.999999985974598 PPIA/PHPT1/DYNLL1/PARK7/MPC2/UQCC2/IDH2/ENY2/HADH/ENSA 10 GO:0007254 JNK cascade 4/719 167/18722 0.887902158258061 0.999999985974598 HMGB1/GSTP1/DUSP9/HRAS 4 GO:0055088 lipid homeostasis 4/719 167/18722 0.887902158258061 0.999999985974598 TMEM97/CD24/CAV1/RALY 4 GO:0042158 lipoprotein biosynthetic process 2/719 96/18722 0.888008047534912 0.999999985974598 DBI/ZDHHC12 2 GO:0002711 positive regulation of T cell mediated immunity 1/719 56/18722 0.888786303396662 0.999999985974598 HSPD1 1 GO:0002886 regulation of myeloid leukocyte mediated immunity 1/719 56/18722 0.888786303396662 0.999999985974598 VAMP8 1 GO:0006687 glycosphingolipid metabolic process 1/719 56/18722 0.888786303396662 0.999999985974598 BAX 1 GO:0010658 striated muscle cell apoptotic process 1/719 56/18722 0.888786303396662 0.999999985974598 BNIP3 1 GO:0031122 cytoplasmic microtubule organization 1/719 56/18722 0.888786303396662 0.999999985974598 TUBG1 1 GO:0042733 embryonic digit morphogenesis 1/719 56/18722 0.888786303396662 0.999999985974598 BAX 1 GO:0045071 negative regulation of viral genome replication 1/719 56/18722 0.888786303396662 0.999999985974598 BANF1 1 GO:0051058 negative regulation of small GTPase mediated signal transduction 1/719 56/18722 0.888786303396662 0.999999985974598 STMN1 1 GO:0055078 sodium ion homeostasis 1/719 56/18722 0.888786303396662 0.999999985974598 COMT 1 GO:1904645 response to amyloid-beta 1/719 56/18722 0.888786303396662 0.999999985974598 PARP1 1 GO:1990089 response to nerve growth factor 1/719 56/18722 0.888786303396662 0.999999985974598 ID1 1 GO:0035592 establishment of protein localization to extracellular region 10/719 360/18722 0.889104510637793 0.999999985974598 PPIA/PHPT1/DYNLL1/PARK7/MPC2/UQCC2/IDH2/ENY2/HADH/ENSA 10 GO:0050863 regulation of T cell activation 9/719 329/18722 0.889168950065951 0.999999985974598 HMGB1/PRDX2/RPS3/SOD1/PRELID1/CD24/HSPD1/CAV1/PNP 9 GO:0010595 positive regulation of endothelial cell migration 3/719 133/18722 0.889736449045351 0.999999985974598 HMGB1/ANXA3/ITGB1BP1 3 GO:0046328 regulation of JNK cascade 3/719 133/18722 0.889736449045351 0.999999985974598 HMGB1/GSTP1/HRAS 3 GO:0006816 calcium ion transport 12/719 422/18722 0.890320297837344 0.999999985974598 CALM2/GSTO1/TPT1/CALM1/VDAC1/ANXA2/YWHAE/CAV1/STOML2/C4orf3/BAX/MCUR1 12 GO:0042060 wound healing 12/719 422/18722 0.890320297837344 0.999999985974598 HMGB1/PPIA/PRDX2/ANXA5/ACTG1/ANXA2/GNAS/CAV1/RHOC/VKORC1/HRAS/FIBP 12 GO:0043255 regulation of carbohydrate biosynthetic process 2/719 97/18722 0.891435821010962 0.999999985974598 PPP1CA/PGP 2 GO:0070252 actin-mediated cell contraction 2/719 97/18722 0.891435821010962 0.999999985974598 MYL6/CAV1 2 GO:0008277 regulation of G protein-coupled receptor signaling pathway 3/719 134/18722 0.892674366636706 0.999999985974598 STMN1/DYNLT1/PHB 3 GO:0098727 maintenance of cell number 3/719 134/18722 0.892674366636706 0.999999985974598 TPT1/EZH2/SMC3 3 GO:0002011 morphogenesis of an epithelial sheet 1/719 57/18722 0.893070169669983 0.999999985974598 RHOC 1 GO:0034205 amyloid-beta formation 1/719 57/18722 0.893070169669983 0.999999985974598 PIN1 1 GO:0060760 positive regulation of response to cytokine stimulus 1/719 57/18722 0.893070169669983 0.999999985974598 TAF9 1 GO:0061005 cell differentiation involved in kidney development 1/719 57/18722 0.893070169669983 0.999999985974598 CD24 1 GO:1902017 regulation of cilium assembly 1/719 57/18722 0.893070169669983 0.999999985974598 VDAC3 1 GO:0001894 tissue homeostasis 7/719 268/18722 0.893589345716024 0.999999985974598 PRDX1/ACTG1/SOD1/AKR1B1/FH/MKKS/BAX 7 GO:0002237 response to molecule of bacterial origin 10/719 363/18722 0.894685160446014 0.999999985974598 HMGB2/HMGB1/PRDX2/GSTP1/COMT/CD24/HSPD1/PRDX3/ADH5/CDK4 10 GO:0032642 regulation of chemokine production 2/719 98/18722 0.894765968124319 0.999999985974598 HMGB1/GSTP1 2 GO:0043473 pigmentation 2/719 98/18722 0.894765968124319 0.999999985974598 MKKS/BAX 2 GO:0042886 amide transport 8/719 301/18722 0.895920923234885 0.999999985974598 PHPT1/DYNLL1/PARK7/MPC2/UQCC2/ENY2/HADH/ENSA 8 GO:1903131 mononuclear cell differentiation 12/719 426/18722 0.897146840089667 0.999999985974598 HMGB1/PRDX2/SLC25A5/RPS6/RPL22/SOD1/PRELID1/XRCC6/EZH2/PNP/PIR/BAX 12 GO:0006826 iron ion transport 1/719 58/18722 0.897189245373561 0.999999985974598 ISCU 1 GO:0010574 regulation of vascular endothelial growth factor production 1/719 58/18722 0.897189245373561 0.999999985974598 NUTF2 1 GO:0034340 response to type I interferon 1/719 58/18722 0.897189245373561 0.999999985974598 HSP90AB1 1 GO:0045604 regulation of epidermal cell differentiation 1/719 58/18722 0.897189245373561 0.999999985974598 EZH2 1 GO:0050432 catecholamine secretion 1/719 58/18722 0.897189245373561 0.999999985974598 LY6E 1 GO:2000649 regulation of sodium ion transmembrane transporter activity 1/719 58/18722 0.897189245373561 0.999999985974598 YWHAH 1 GO:0032602 chemokine production 2/719 99/18722 0.898000918563598 0.999999985974598 HMGB1/GSTP1 2 GO:0042129 regulation of T cell proliferation 4/719 171/18722 0.898326984973335 0.999999985974598 HMGB1/RPS3/CD24/PNP 4 GO:0048469 cell maturation 4/719 171/18722 0.898326984973335 0.999999985974598 TYMS/CCNB1/AURKA/AKR1B1 4 GO:0003158 endothelium development 3/719 136/18722 0.898340463739653 0.999999985974598 EDF1/CSNK2B/ID1 3 GO:1903039 positive regulation of leukocyte cell-cell adhesion 6/719 239/18722 0.900735113843868 0.999999985974598 HMGB1/RPS3/CD24/HSPD1/CAV1/PNP 6 GO:0007266 Rho protein signal transduction 3/719 137/18722 0.901071361126521 0.999999985974598 STMN1/CFL1/CTNNAL1 3 GO:0034754 cellular hormone metabolic process 3/719 137/18722 0.901071361126521 0.999999985974598 COMT/AKR1B1/HSD17B10 3 GO:0051588 regulation of neurotransmitter transport 2/719 100/18722 0.901143059691481 0.999999985974598 CALM1/PNKD 2 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 1/719 59/18722 0.901149861135263 0.999999985974598 CAV1 1 GO:0051055 negative regulation of lipid biosynthetic process 1/719 59/18722 0.901149861135263 0.999999985974598 SOD1 1 GO:1903706 regulation of hemopoiesis 10/719 367/18722 0.901763176938733 0.999999985974598 HMGB2/HMGB1/PRDX2/SOD1/NME1/PRELID1/XRCC6/EIF6/PNP/PRMT1 10 GO:0050851 antigen receptor-mediated signaling pathway 6/719 240/18722 0.902822632785722 0.999999985974598 RPS3/PHPT1/UBE2N/STOML2/HRAS/BAX 6 GO:0010469 regulation of signaling receptor activity 4/719 173/18722 0.903212217524973 0.999999985974598 LY6E/PARK7/PHLDA2/BUD31 4 GO:0071692 protein localization to extracellular region 10/719 368/18722 0.903469493472661 0.999999985974598 PPIA/PHPT1/DYNLL1/PARK7/MPC2/UQCC2/IDH2/ENY2/HADH/ENSA 10 GO:0001539 cilium or flagellum-dependent cell motility 3/719 138/18722 0.903735947876335 0.999999985974598 SLIRP/CFAP20/MKKS 3 GO:0060285 cilium-dependent cell motility 3/719 138/18722 0.903735947876335 0.999999985974598 SLIRP/CFAP20/MKKS 3 GO:0007265 Ras protein signal transduction 9/719 337/18722 0.904092728500305 0.999999985974598 STMN1/CCNA2/PARK7/CFL1/DYNLT1/CTNNAL1/CDKN2A/DNMT1/HRAS 9 GO:0006476 protein deacetylation 2/719 101/18722 0.904194736208274 0.999999985974598 MORF4L2/PHB 2 GO:0050830 defense response to Gram-positive bacterium 2/719 101/18722 0.904194736208274 0.999999985974598 HMGB2/ROMO1 2 GO:0006893 Golgi to plasma membrane transport 1/719 60/18722 0.904958104710452 0.999999985974598 KRT18 1 GO:0009620 response to fungus 1/719 60/18722 0.904958104710452 0.999999985974598 GAPDH 1 GO:0031102 neuron projection regeneration 1/719 60/18722 0.904958104710452 0.999999985974598 DHFR 1 GO:0031638 zymogen activation 1/719 60/18722 0.904958104710452 0.999999985974598 ENO1 1 GO:0031663 lipopolysaccharide-mediated signaling pathway 1/719 60/18722 0.904958104710452 0.999999985974598 PRDX2 1 GO:0055008 cardiac muscle tissue morphogenesis 1/719 60/18722 0.904958104710452 0.999999985974598 LY6E 1 GO:0002573 myeloid leukocyte differentiation 5/719 208/18722 0.905376598909735 0.999999985974598 NME1/ANXA2/GLO1/PARP1/PIR 5 GO:0048639 positive regulation of developmental growth 4/719 174/18722 0.905576179962097 0.999999985974598 CDK1/CCNB1/MKKS/PIN1 4 GO:0001841 neural tube formation 2/719 102/18722 0.907158249903576 0.999999985974598 PFN1/RPS7 2 GO:0032677 regulation of interleukin-8 production 2/719 102/18722 0.907158249903576 0.999999985974598 HMGB1/PARK7 2 GO:0035710 CD4-positive, alpha-beta T cell activation 2/719 102/18722 0.907158249903576 0.999999985974598 HMGB1/STOML2 2 GO:0002366 leukocyte activation involved in immune response 7/719 275/18722 0.907509032809583 0.999999985974598 HMGB1/RPS6/ANXA3/UNG/HSPD1/S100A13/VAMP8 7 GO:0071222 cellular response to lipopolysaccharide 5/719 209/18722 0.907516886406027 0.999999985974598 HMGB2/HMGB1/PRDX2/GSTP1/CDK4 5 GO:1905475 regulation of protein localization to membrane 4/719 175/18722 0.907888889181411 0.999999985974598 PDCD5/VAMP8/HRAS/ITGB1BP1 4 GO:0030199 collagen fibril organization 1/719 61/18722 0.908619830287195 0.999999985974598 ANXA2 1 GO:0050994 regulation of lipid catabolic process 1/719 61/18722 0.908619830287195 0.999999985974598 CDK4 1 GO:0060997 dendritic spine morphogenesis 1/719 61/18722 0.908619830287195 0.999999985974598 CFL1 1 GO:1905515 non-motile cilium assembly 1/719 61/18722 0.908619830287195 0.999999985974598 MKKS 1 GO:0016358 dendrite development 6/719 243/18722 0.908860219031182 0.999999985974598 YWHAH/CDC20/CFL1/DYNLT1/EZH2/ID1 6 GO:0045637 regulation of myeloid cell differentiation 5/719 210/18722 0.909614779441935 0.999999985974598 HMGB2/HMGB1/NME1/EIF6/PRMT1 5 GO:0060537 muscle tissue development 11/719 403/18722 0.909704278282541 0.999999985974598 CDK1/CSRP2/CCNB1/CACYBP/LY6E/UQCC2/MYL6/NDUFV2/CAV1/PRMT1/PIN1 11 GO:0030593 neutrophil chemotaxis 2/719 103/18722 0.910035859489815 0.999999985974598 PPIA/C1QBP 2 GO:0032637 interleukin-8 production 2/719 103/18722 0.910035859489815 0.999999985974598 HMGB1/PARK7 2 GO:0046425 regulation of receptor signaling pathway via JAK-STAT 2/719 103/18722 0.910035859489815 0.999999985974598 CAV1/AKR1B1 2 GO:0043534 blood vessel endothelial cell migration 4/719 176/18722 0.910151224715457 0.999999985974598 HMGB1/CSNK2B/ID1/ITGB1BP1 4 GO:0006898 receptor-mediated endocytosis 6/719 244/18722 0.910799432452204 0.999999985974598 ANXA2/AP2S1/CLTA/CAV1/CLTB/AP1S1 6 GO:0030183 B cell differentiation 3/719 141/18722 0.911345026717642 0.999999985974598 SLC25A5/EZH2/BAX 3 GO:0010573 vascular endothelial growth factor production 1/719 62/18722 0.912140667435446 0.999999985974598 NUTF2 1 GO:0032731 positive regulation of interleukin-1 beta production 1/719 62/18722 0.912140667435446 0.999999985974598 HMGB1 1 GO:0032835 glomerulus development 1/719 62/18722 0.912140667435446 0.999999985974598 CD24 1 GO:0060113 inner ear receptor cell differentiation 1/719 62/18722 0.912140667435446 0.999999985974598 SOD1 1 GO:0030324 lung development 4/719 177/18722 0.912364059685942 0.999999985974598 HMGB1/PTGES3/HSPB11/PPP1CA 4 GO:0060326 cell chemotaxis 8/719 310/18722 0.912397530733038 0.999999985974598 HMGB2/HMGB1/PPIA/GSTP1/RPS19/MIF/C1QBP/DDT 8 GO:0070663 regulation of leukocyte proliferation 6/719 245/18722 0.912702822449303 0.999999985974598 HMGB1/GSTP1/RPS3/MIF/CD24/PNP 6 GO:0032006 regulation of TOR signaling 2/719 104/18722 0.912829780511733 0.999999985974598 PIH1D1/RHEB 2 GO:0045621 positive regulation of lymphocyte differentiation 2/719 104/18722 0.912829780511733 0.999999985974598 XRCC6/PNP 2 GO:0046634 regulation of alpha-beta T cell activation 2/719 104/18722 0.912829780511733 0.999999985974598 HMGB1/PNP 2 GO:0032496 response to lipopolysaccharide 9/719 343/18722 0.914145833061465 0.999999985974598 HMGB2/HMGB1/PRDX2/GSTP1/COMT/HSPD1/PRDX3/ADH5/CDK4 9 GO:0010959 regulation of metal ion transport 11/719 406/18722 0.91423782751641 0.999999985974598 CALM2/GSTO1/CALM1/YWHAH/VDAC1/YWHAE/CAV1/C4orf3/SUMO1/ISCU/BAX 11 GO:0002764 immune response-regulating signaling pathway 13/719 468/18722 0.914356270457581 0.999999985974598 HMGB1/RPS3/PHPT1/CD24/UBE2N/HSPD1/C1QBP/CAV1/STOML2/PHB/PHB2/HRAS/BAX 13 GO:0002263 cell activation involved in immune response 7/719 279/18722 0.914741701511689 0.999999985974598 HMGB1/RPS6/ANXA3/UNG/HSPD1/S100A13/VAMP8 7 GO:1902105 regulation of leukocyte differentiation 7/719 279/18722 0.914741701511689 0.999999985974598 HMGB1/PRDX2/SOD1/NME1/PRELID1/XRCC6/PNP 7 GO:0001947 heart looping 1/719 63/18722 0.915526029713791 0.999999985974598 MKKS 1 GO:0000041 transition metal ion transport 2/719 105/18722 0.915542185326256 0.999999985974598 COX17/ISCU 2 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 2/719 105/18722 0.915542185326256 0.999999985974598 PFN1/HRAS 2 GO:0001505 regulation of neurotransmitter levels 5/719 213/18722 0.91566051808142 0.999999985974598 CALM1/PARK7/COMT/PNKD/SLC29A1 5 GO:0006906 vesicle fusion 2/719 106/18722 0.918175203147487 0.999999985974598 ANXA2/VAMP8 2 GO:0015698 inorganic anion transport 4/719 180/18722 0.918714189377725 0.999999985974598 SLC25A3/VDAC1/VDAC3/VDAC2 4 GO:0030858 positive regulation of epithelial cell differentiation 1/719 64/18722 0.918781122946857 0.999999985974598 CD24 1 GO:0030888 regulation of B cell proliferation 1/719 64/18722 0.918781122946857 0.999999985974598 MIF 1 GO:0046854 phosphatidylinositol phosphate biosynthetic process 1/719 64/18722 0.918781122946857 0.999999985974598 IMPA2 1 GO:1900076 regulation of cellular response to insulin stimulus 1/719 64/18722 0.918781122946857 0.999999985974598 NUCKS1 1 GO:0060249 anatomical structure homeostasis 8/719 314/18722 0.918974908376289 0.999999985974598 PRDX1/ALDOA/ACTG1/SOD1/AKR1B1/FH/MKKS/BAX 8 GO:0061351 neural precursor cell proliferation 3/719 145/18722 0.920640836943347 0.999999985974598 RRM1/NAP1L1/PSMG1 3 GO:0031532 actin cytoskeleton reorganization 2/719 107/18722 0.920730920151863 0.999999985974598 PHPT1/HRAS 2 GO:0032526 response to retinoic acid 2/719 107/18722 0.920730920151863 0.999999985974598 NDUFA13/PHB2 2 GO:0030323 respiratory tube development 4/719 181/18722 0.920737613795251 0.999999985974598 HMGB1/PTGES3/HSPB11/PPP1CA 4 GO:0002377 immunoglobulin production 5/719 216/18722 0.921347695801616 0.999999985974598 UNG/CTNNBL1/HSPD1/PHB/PHB2 5 GO:0071560 cellular response to transforming growth factor beta stimulus 6/719 250/18722 0.921699790177174 0.999999985974598 HSP90AB1/PDCD5/CAV1/PARP1/PIN1/ID1 6 GO:0006487 protein N-linked glycosylation 1/719 65/18722 0.921910953185961 0.999999985974598 OST4 1 GO:0046503 glycerolipid catabolic process 1/719 65/18722 0.921910953185961 0.999999985974598 PRDX6 1 GO:1905330 regulation of morphogenesis of an epithelium 1/719 65/18722 0.921910953185961 0.999999985974598 PHB2 1 GO:0048813 dendrite morphogenesis 3/719 146/18722 0.922821399905671 0.999999985974598 YWHAH/CFL1/ID1 3 GO:0050678 regulation of epithelial cell proliferation 10/719 381/18722 0.923484865164901 0.999999985974598 HMGB2/HMGB1/NME1/HMGN1/CAV1/CCND1/PHB2/HRAS/ID1/BAX 10 GO:0016055 Wnt signaling pathway 12/719 444/18722 0.923679864434859 0.999999985974598 RPS12/CCNE1/RBX1/CD24/PPP1CA/CSNK2B/CAV1/SNX3/CCND1/MDFI/PIN1/RUVBL1 12 GO:0032535 regulation of cellular component size 10/719 382/18722 0.924866412801077 0.999999985974598 NPM1/PFN1/DSTN/HSP90AB1/PPP1CA/ARPC1A/ARPC5/CDK4/ARPC5L/MKKS 10 GO:0014015 positive regulation of gliogenesis 1/719 66/18722 0.924920334365105 0.999999985974598 RHEB 1 GO:0019229 regulation of vasoconstriction 1/719 66/18722 0.924920334365105 0.999999985974598 CAV1 1 GO:0042093 T-helper cell differentiation 1/719 66/18722 0.924920334365105 0.999999985974598 HMGB1 1 GO:0042446 hormone biosynthetic process 1/719 66/18722 0.924920334365105 0.999999985974598 AKR1B1 1 GO:0045600 positive regulation of fat cell differentiation 1/719 66/18722 0.924920334365105 0.999999985974598 ADIRF 1 GO:0050766 positive regulation of phagocytosis 1/719 66/18722 0.924920334365105 0.999999985974598 SOD1 1 GO:2000272 negative regulation of signaling receptor activity 1/719 66/18722 0.924920334365105 0.999999985974598 LY6E 1 GO:1902652 secondary alcohol metabolic process 3/719 147/18722 0.924947032725662 0.999999985974598 SOD1/FDPS/IDH2 3 GO:0002456 T cell mediated immunity 2/719 109/18722 0.925618582242457 0.999999985974598 HMGB1/HSPD1 2 GO:0198738 cell-cell signaling by wnt 12/719 446/18722 0.926235357005761 0.999999985974598 RPS12/CCNE1/RBX1/CD24/PPP1CA/CSNK2B/CAV1/SNX3/CCND1/MDFI/PIN1/RUVBL1 12 GO:0034612 response to tumor necrosis factor 6/719 253/18722 0.92669965397208 0.999999985974598 GSTP1/RPS3/KRT8/KRT18/EIF5A/TXNDC17 6 GO:0060828 regulation of canonical Wnt signaling pathway 6/719 253/18722 0.92669965397208 0.999999985974598 RPS12/RBX1/PPP1CA/CAV1/PIN1/RUVBL1 6 GO:0035148 tube formation 3/719 148/18722 0.927018918909442 0.999999985974598 PFN1/RPS7/ITGB1BP1 3 GO:0050905 neuromuscular process 3/719 148/18722 0.927018918909442 0.999999985974598 GSTO1/C12orf57/PNKD 3 GO:0014706 striated muscle tissue development 10/719 384/18722 0.927565663456911 0.999999985974598 CDK1/CCNB1/CACYBP/LY6E/UQCC2/MYL6/NDUFV2/CAV1/PRMT1/PIN1 10 GO:0035914 skeletal muscle cell differentiation 1/719 67/18722 0.927813895663963 0.999999985974598 UQCC2 1 GO:0042490 mechanoreceptor differentiation 1/719 67/18722 0.927813895663963 0.999999985974598 SOD1 1 GO:0046635 positive regulation of alpha-beta T cell activation 1/719 67/18722 0.927813895663963 0.999999985974598 PNP 1 GO:0050435 amyloid-beta metabolic process 1/719 67/18722 0.927813895663963 0.999999985974598 PIN1 1 GO:0061371 determination of heart left/right asymmetry 1/719 67/18722 0.927813895663963 0.999999985974598 MKKS 1 GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 1/719 67/18722 0.927813895663963 0.999999985974598 HMGB1 1 GO:0003014 renal system process 2/719 110/18722 0.927954486190339 0.999999985974598 COMT/AKR1B1 2 GO:0032611 interleukin-1 beta production 2/719 110/18722 0.927954486190339 0.999999985974598 HMGB1/GSTP1 2 GO:0032651 regulation of interleukin-1 beta production 2/719 110/18722 0.927954486190339 0.999999985974598 HMGB1/GSTP1 2 GO:0090174 organelle membrane fusion 2/719 110/18722 0.927954486190339 0.999999985974598 ANXA2/VAMP8 2 GO:0071496 cellular response to external stimulus 8/719 320/18722 0.928044096716541 0.999999985974598 GSTP1/HNRNPA1/COMT/DCTPP1/NUDT1/NUDT15/TXN2/BNIP3 8 GO:0002064 epithelial cell development 5/719 220/18722 0.928401990517155 0.999999985974598 TYMS/SOD1/AKR1B1/RAB25/RHEB 5 GO:0006874 cellular calcium ion homeostasis 12/719 448/18722 0.928717906148433 0.999999985974598 HMGB1/CALM2/GSTO1/TPT1/CALM1/CD24/YWHAE/CAV1/STOML2/BNIP3/BAX/MCUR1 12 GO:0071219 cellular response to molecule of bacterial origin 5/719 221/18722 0.930075252190438 0.999999985974598 HMGB2/HMGB1/PRDX2/GSTP1/CDK4 5 GO:0050727 regulation of inflammatory response 10/719 386/18722 0.9301814050598 0.999999985974598 GSTP1/PBK/RPS19/SOD1/PARK7/GPX4/HSPD1/VAMP8/DDT/PSMB4 10 GO:0120032 regulation of plasma membrane bounded cell projection assembly 4/719 186/18722 0.930192543802634 0.999999985974598 PFN1/VDAC3/CAV1/HRAS 4 GO:0001938 positive regulation of endothelial cell proliferation 2/719 111/18722 0.930221007605056 0.999999985974598 HMGB2/HMGB1 2 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 1/719 68/18722 0.930596088589056 0.999999985974598 HMGB1 1 GO:0034394 protein localization to cell surface 1/719 68/18722 0.930596088589056 0.999999985974598 HSP90AB1 1 GO:0042698 ovulation cycle 1/719 68/18722 0.930596088589056 0.999999985974598 PCNA 1 GO:0042987 amyloid precursor protein catabolic process 1/719 68/18722 0.930596088589056 0.999999985974598 PIN1 1 GO:1902305 regulation of sodium ion transmembrane transport 1/719 68/18722 0.930596088589056 0.999999985974598 YWHAH 1 GO:0043010 camera-type eye development 8/719 322/18722 0.930865204880724 0.999999985974598 RPL24/RRM1/IMPDH2/HMGN1/C12orf57/ACTL6A/CDK4/BAX 8 GO:0071559 response to transforming growth factor beta 6/719 256/18722 0.931416719314705 0.999999985974598 HSP90AB1/PDCD5/CAV1/PARP1/PIN1/ID1 6 GO:1903522 regulation of blood circulation 6/719 256/18722 0.931416719314705 0.999999985974598 CALM2/GSTO1/CALM1/YWHAE/CAV1/GLRX3 6 GO:0016049 cell growth 13/719 482/18722 0.931989124135853 0.999999985974598 ENO1/NPM1/AURKA/TMEM97/HSP90AB1/HSP90AA1/DNPH1/RBBP7/CDKN2A/NDUFA13/PHB/PIN1/NDUFS3 13 GO:0002526 acute inflammatory response 2/719 112/18722 0.932420020845338 0.999999985974598 GSTP1/PARK7 2 GO:0035601 protein deacylation 2/719 112/18722 0.932420020845338 0.999999985974598 MORF4L2/PHB 2 GO:0043535 regulation of blood vessel endothelial cell migration 3/719 151/18722 0.932923675720417 0.999999985974598 HMGB1/CSNK2B/ITGB1BP1 3 GO:0048592 eye morphogenesis 3/719 151/18722 0.932923675720417 0.999999985974598 HMGN1/C12orf57/BAX 3 GO:0002287 alpha-beta T cell activation involved in immune response 1/719 69/18722 0.933271193783892 0.999999985974598 HMGB1 1 GO:0002293 alpha-beta T cell differentiation involved in immune response 1/719 69/18722 0.933271193783892 0.999999985974598 HMGB1 1 GO:0003143 embryonic heart tube morphogenesis 1/719 69/18722 0.933271193783892 0.999999985974598 MKKS 1 GO:0019226 transmission of nerve impulse 1/719 69/18722 0.933271193783892 0.999999985974598 SOD1 1 GO:0033344 cholesterol efflux 1/719 69/18722 0.933271193783892 0.999999985974598 CAV1 1 GO:0050805 negative regulation of synaptic transmission 1/719 69/18722 0.933271193783892 0.999999985974598 PNKD 1 GO:0050810 regulation of steroid biosynthetic process 1/719 69/18722 0.933271193783892 0.999999985974598 SOD1 1 GO:0050920 regulation of chemotaxis 5/719 223/18722 0.933317601237371 0.999999985974598 HMGB1/GSTP1/MIF/C1QBP/DDT 5 GO:0060491 regulation of cell projection assembly 4/719 188/18722 0.933680595510963 0.999999985974598 PFN1/VDAC3/CAV1/HRAS 4 GO:0031348 negative regulation of defense response 6/719 258/18722 0.934410629343572 0.999999985974598 GSTP1/PBK/RPS19/SOD1/C1QBP/PSMB4 6 GO:0044344 cellular response to fibroblast growth factor stimulus 2/719 113/18722 0.934553358882981 0.999999985974598 FIBP/ITGB1BP1 2 GO:0003407 neural retina development 1/719 70/18722 0.935843327578423 0.999999985974598 ACTL6A 1 GO:0060415 muscle tissue morphogenesis 1/719 70/18722 0.935843327578423 0.999999985974598 LY6E 1 GO:0072503 cellular divalent inorganic cation homeostasis 13/719 486/18722 0.936421235016773 0.999999985974598 HMGB1/MT2A/CALM2/GSTO1/TPT1/CALM1/CD24/YWHAE/CAV1/STOML2/BNIP3/BAX/MCUR1 13 GO:0010001 glial cell differentiation 5/719 225/18722 0.936424971789108 0.999999985974598 CDK1/GSTP1/SOD1/RHEB/BNIP3 5 GO:0050670 regulation of lymphocyte proliferation 5/719 225/18722 0.936424971789108 0.999999985974598 HMGB1/RPS3/MIF/CD24/PNP 5 GO:0002286 T cell activation involved in immune response 2/719 114/18722 0.936622813712419 0.999999985974598 HMGB1/RPS6 2 GO:1904892 regulation of receptor signaling pathway via STAT 2/719 114/18722 0.936622813712419 0.999999985974598 CAV1/AKR1B1 2 GO:2000146 negative regulation of cell motility 9/719 359/18722 0.936676259432478 0.999999985974598 HMGB1/GSTP1/MIF/IDH2/CSNK2B/APEX1/DDT/PIN1/ITGB1BP1 9 GO:0042110 T cell activation 13/719 487/18722 0.937489870012919 0.999999985974598 HMGB1/PRDX2/RPS3/RPS6/RPL22/SOD1/PRELID1/CD24/HSPD1/CAV1/STOML2/PNP/BAX 13 GO:0003208 cardiac ventricle morphogenesis 1/719 71/18722 0.93831644828779 0.999999985974598 LY6E 1 GO:0008344 adult locomotory behavior 1/719 71/18722 0.93831644828779 0.999999985974598 PARK7 1 GO:0032722 positive regulation of chemokine production 1/719 71/18722 0.93831644828779 0.999999985974598 HMGB1 1 GO:0045824 negative regulation of innate immune response 1/719 71/18722 0.93831644828779 0.999999985974598 RPS19 1 GO:0050795 regulation of behavior 1/719 71/18722 0.93831644828779 0.999999985974598 CFAP20 1 GO:0008360 regulation of cell shape 3/719 154/18722 0.938385664836773 0.999999985974598 ALDOA/MYL12B/RHOC 3 GO:0071675 regulation of mononuclear cell migration 2/719 115/18722 0.938630136789892 0.999999985974598 HMGB1/C1QBP 2 GO:0030111 regulation of Wnt signaling pathway 8/719 328/18722 0.938758921979464 0.999999985974598 RPS12/RBX1/PPP1CA/CAV1/SNX3/MDFI/PIN1/RUVBL1 8 GO:0032944 regulation of mononuclear cell proliferation 5/719 227/18722 0.939401990329499 0.999999985974598 HMGB1/RPS3/MIF/CD24/PNP 5 GO:0007519 skeletal muscle tissue development 3/719 155/18722 0.940113012694718 0.999999985974598 UQCC2/MYL6/CAV1 3 GO:0008286 insulin receptor signaling pathway 2/719 116/18722 0.940577039499324 0.999999985974598 NUCKS1/CDK4 2 GO:0021782 glial cell development 2/719 116/18722 0.940577039499324 0.999999985974598 GSTP1/SOD1 2 GO:0098732 macromolecule deacylation 2/719 116/18722 0.940577039499324 0.999999985974598 MORF4L2/PHB 2 GO:0002534 cytokine production involved in inflammatory response 1/719 72/18722 0.94069436226994 0.999999985974598 EZH2 1 GO:0033627 cell adhesion mediated by integrin 1/719 72/18722 0.94069436226994 0.999999985974598 ITGB1BP1 1 GO:1900015 regulation of cytokine production involved in inflammatory response 1/719 72/18722 0.94069436226994 0.999999985974598 EZH2 1 GO:0001935 endothelial cell proliferation 4/719 193/18722 0.941720515535207 0.999999985974598 HMGB2/HMGB1/CAV1/ITGB1BP1 4 GO:0055074 calcium ion homeostasis 12/719 460/18722 0.942165824920228 0.999999985974598 HMGB1/CALM2/GSTO1/TPT1/CALM1/CD24/YWHAE/CAV1/STOML2/BNIP3/BAX/MCUR1 12 GO:0002702 positive regulation of production of molecular mediator of immune response 2/719 117/18722 0.942465193642216 0.999999985974598 PHB/PHB2 2 GO:0030301 cholesterol transport 2/719 117/18722 0.942465193642216 0.999999985974598 ANXA2/CAV1 2 GO:0050767 regulation of neurogenesis 9/719 364/18722 0.942572728106483 0.999999985974598 HMGB2/YWHAH/DYNLT1/IDH2/NAP1L1/EZH2/FAIM/RHEB/ID1 9 GO:0035924 cellular response to vascular endothelial growth factor stimulus 1/719 73/18722 0.942980729751329 0.999999985974598 ITGB1BP1 1 GO:0051145 smooth muscle cell differentiation 1/719 73/18722 0.942980729751329 0.999999985974598 DNMT1 1 GO:0051298 centrosome duplication 1/719 73/18722 0.942980729751329 0.999999985974598 NPM1 1 GO:0070988 demethylation 1/719 73/18722 0.942980729751329 0.999999985974598 APEX1 1 GO:0086003 cardiac muscle cell contraction 1/719 73/18722 0.942980729751329 0.999999985974598 CAV1 1 GO:0002285 lymphocyte activation involved in immune response 4/719 194/18722 0.943217887732443 0.999999985974598 HMGB1/RPS6/UNG/HSPD1 4 GO:0007030 Golgi organization 3/719 157/18722 0.943434026368266 0.999999985974598 CDK1/VRK1/NSFL1C 3 GO:1902107 positive regulation of leukocyte differentiation 3/719 157/18722 0.943434026368266 0.999999985974598 HMGB1/XRCC6/PNP 3 GO:1903708 positive regulation of hemopoiesis 3/719 157/18722 0.943434026368266 0.999999985974598 HMGB1/XRCC6/PNP 3 GO:0007613 memory 2/719 118/18722 0.94429623194905 0.999999985974598 FEN1/COMT 2 GO:0045446 endothelial cell differentiation 2/719 118/18722 0.94429623194905 0.999999985974598 EDF1/ID1 2 GO:1990778 protein localization to cell periphery 8/719 333/18722 0.944721973305079 0.999999985974598 S100A10/ANXA2/KRT18/CAV1/VAMP8/NSG1/HRAS/ITGB1BP1 8 GO:0046470 phosphatidylcholine metabolic process 1/719 74/18722 0.945179070429585 0.999999985974598 DBI 1 GO:0042113 B cell activation 8/719 334/18722 0.94585119491679 0.999999985974598 SLC25A5/MIF/UNG/HSPD1/EZH2/PHB/PHB2/BAX 8 GO:0051271 negative regulation of cellular component movement 9/719 367/18722 0.945875064234844 0.999999985974598 HMGB1/GSTP1/MIF/IDH2/CSNK2B/APEX1/DDT/PIN1/ITGB1BP1 9 GO:0042063 gliogenesis 7/719 301/18722 0.946392270984936 0.999999985974598 CDK1/GSTP1/SOD1/IDH2/EZH2/RHEB/BNIP3 7 GO:0002292 T cell differentiation involved in immune response 1/719 75/18722 0.947292768861649 0.999999985974598 HMGB1 1 GO:0045913 positive regulation of carbohydrate metabolic process 1/719 75/18722 0.947292768861649 0.999999985974598 HMGB1 1 GO:0048675 axon extension 2/719 120/18722 0.947793299821391 0.999999985974598 HSP90AB1/HSP90AA1 2 GO:0071774 response to fibroblast growth factor 2/719 120/18722 0.947793299821391 0.999999985974598 FIBP/ITGB1BP1 2 GO:0048167 regulation of synaptic plasticity 4/719 198/18722 0.948862681712389 0.999999985974598 YWHAH/CDC20/NSG1/HRAS 4 GO:0001937 negative regulation of endothelial cell proliferation 1/719 76/18722 0.949325079645608 0.999999985974598 CAV1 1 GO:0032720 negative regulation of tumor necrosis factor production 1/719 76/18722 0.949325079645608 0.999999985974598 GSTP1 1 GO:0043536 positive regulation of blood vessel endothelial cell migration 1/719 76/18722 0.949325079645608 0.999999985974598 HMGB1 1 GO:0140029 exocytic process 1/719 76/18722 0.949325079645608 0.999999985974598 VAMP8 1 GO:0001838 embryonic epithelial tube formation 2/719 121/18722 0.949462404349912 0.999999985974598 PFN1/RPS7 2 GO:1904019 epithelial cell apoptotic process 2/719 121/18722 0.949462404349912 0.999999985974598 KRT8/KRT18 2 GO:0001654 eye development 9/719 371/18722 0.950017967664062 0.999999985974598 HMGB1/RPL24/RRM1/IMPDH2/HMGN1/C12orf57/ACTL6A/CDK4/BAX 9 GO:0002699 positive regulation of immune effector process 5/719 235/18722 0.950095774238931 0.999999985974598 RPS19/HSPD1/VAMP8/PHB/PHB2 5 GO:0050673 epithelial cell proliferation 11/719 437/18722 0.950845413361803 0.999999985974598 HMGB2/HMGB1/NME1/HMGN1/CAV1/CCND1/PHB2/HRAS/ID1/ITGB1BP1/BAX 11 GO:0050868 negative regulation of T cell activation 2/719 122/18722 0.95108054410582 0.999999985974598 HMGB1/PRDX2 2 GO:1990266 neutrophil migration 2/719 122/18722 0.95108054410582 0.999999985974598 PPIA/C1QBP 2 GO:0007492 endoderm development 1/719 77/18722 0.951279132404098 0.999999985974598 HSBP1 1 GO:0021675 nerve development 1/719 77/18722 0.951279132404098 0.999999985974598 RPL24 1 GO:0031016 pancreas development 1/719 77/18722 0.951279132404098 0.999999985974598 RHEB 1 GO:0048644 muscle organ morphogenesis 1/719 77/18722 0.951279132404098 0.999999985974598 LY6E 1 GO:0061025 membrane fusion 3/719 163/18722 0.952399300043355 0.999999985974598 ANXA2/VAMP8/NSFL1C 3 GO:0035050 embryonic heart tube development 1/719 78/18722 0.953157936576876 0.999999985974598 MKKS 1 GO:0061045 negative regulation of wound healing 1/719 78/18722 0.953157936576876 0.999999985974598 ANXA2 1 GO:0090049 regulation of cell migration involved in sprouting angiogenesis 1/719 78/18722 0.953157936576876 0.999999985974598 ITGB1BP1 1 GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 1/719 78/18722 0.953157936576876 0.999999985974598 GSTP1 1 GO:0150063 visual system development 9/719 375/18722 0.95387835490585 0.999999985974598 HMGB1/RPL24/RRM1/IMPDH2/HMGN1/C12orf57/ACTL6A/CDK4/BAX 9 GO:0022604 regulation of cell morphogenesis 7/719 309/18722 0.955004236401359 0.999999985974598 S100A10/ALDOA/CFL1/MYL12B/C1QBP/RHOC/ITGB1BP1 7 GO:0060541 respiratory system development 4/719 203/18722 0.955194354231803 0.999999985974598 HMGB1/PTGES3/HSPB11/PPP1CA 4 GO:0071621 granulocyte chemotaxis 2/719 125/18722 0.955643453382443 0.999999985974598 PPIA/C1QBP 2 GO:1904375 regulation of protein localization to cell periphery 2/719 125/18722 0.955643453382443 0.999999985974598 VAMP8/HRAS 2 GO:0030336 negative regulation of cell migration 8/719 344/18722 0.956068336696003 0.999999985974598 HMGB1/GSTP1/MIF/IDH2/CSNK2B/APEX1/DDT/ITGB1BP1 8 GO:0043112 receptor metabolic process 3/719 166/18722 0.956367390183529 0.999999985974598 ANXA2/CAV1/NSG1 3 GO:0060538 skeletal muscle organ development 3/719 166/18722 0.956367390183529 0.999999985974598 UQCC2/MYL6/CAV1 3 GO:1901888 regulation of cell junction assembly 4/719 204/18722 0.956370670843173 0.999999985974598 S100A10/ACTG1/CAV1/ITGB1BP1 4 GO:0001570 vasculogenesis 1/719 80/18722 0.956701263487583 0.999999985974598 CAV1 1 GO:0060348 bone development 4/719 205/18722 0.957518447669423 0.999999985974598 RPL13/ANXA2/GNAS/VKORC1 4 GO:0060968 regulation of gene silencing 1/719 81/18722 0.95837124479605 0.999999985974598 DNMT1 1 GO:0071260 cellular response to mechanical stimulus 1/719 81/18722 0.95837124479605 0.999999985974598 BNIP3 1 GO:0030048 actin filament-based movement 2/719 127/18722 0.958456132862814 0.999999985974598 MYL6/CAV1 2 GO:0035270 endocrine system development 2/719 127/18722 0.958456132862814 0.999999985974598 LY6E/RHEB 2 GO:0048565 digestive tract development 2/719 127/18722 0.958456132862814 0.999999985974598 TYMS/CCNB1 2 GO:0099173 postsynapse organization 3/719 168/18722 0.958838482626439 0.999999985974598 ACTG1/CFL1/ZDHHC12 3 GO:0001558 regulation of cell growth 10/719 414/18722 0.959085108053495 0.999999985974598 ENO1/NPM1/TMEM97/DNPH1/RBBP7/CDKN2A/NDUFA13/PHB/PIN1/NDUFS3 10 GO:0048880 sensory system development 9/719 381/18722 0.959173548538274 0.999999985974598 HMGB1/RPL24/RRM1/IMPDH2/HMGN1/C12orf57/ACTL6A/CDK4/BAX 9 GO:0007032 endosome organization 1/719 82/18722 0.959976903022091 0.999999985974598 SNX3 1 GO:0008543 fibroblast growth factor receptor signaling pathway 1/719 82/18722 0.959976903022091 0.999999985974598 FIBP 1 GO:0021700 developmental maturation 6/719 280/18722 0.960439146147107 0.999999985974598 TYMS/PFN1/CDC20/CCNB1/AURKA/AKR1B1 6 GO:0002768 immune response-regulating cell surface receptor signaling pathway 7/719 315/18722 0.960625642419762 0.999999985974598 RPS3/PHPT1/CD24/UBE2N/STOML2/HRAS/BAX 7 GO:0006836 neurotransmitter transport 4/719 208/18722 0.960796574722828 0.999999985974598 CALM1/PARK7/PNKD/SLC29A1 4 GO:0006644 phospholipid metabolic process 9/719 383/18722 0.96081409570043 0.999999985974598 DBI/PRDX6/FDPS/GPX4/PGP/IMPA2/STOML2/ISYNA1/PHB2 9 GO:0030178 negative regulation of Wnt signaling pathway 3/719 170/18722 0.961177908130625 0.999999985974598 RBX1/CAV1/MDFI 3 GO:0043367 CD4-positive, alpha-beta T cell differentiation 1/719 83/18722 0.961520712395863 0.999999985974598 HMGB1 1 GO:0071216 cellular response to biotic stimulus 5/719 246/18722 0.962009076056886 0.999999985974598 HMGB2/HMGB1/PRDX2/GSTP1/CDK4 5 GO:0046890 regulation of lipid biosynthetic process 3/719 171/18722 0.962300246044148 0.999999985974598 SOD1/EIF6/CDK4 3 GO:0006959 humoral immune response 7/719 317/18722 0.962353548171708 0.999999985974598 GAPDH/HMGN2/RPS19/RPL30/C1QBP/ROMO1/PHB 7 GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 2/719 130/18722 0.962357068985217 0.999999985974598 TRAPPC1/COPE 2 GO:0006956 complement activation 2/719 130/18722 0.962357068985217 0.999999985974598 C1QBP/PHB 2 GO:0015918 sterol transport 2/719 130/18722 0.962357068985217 0.999999985974598 ANXA2/CAV1 2 GO:0042476 odontogenesis 2/719 130/18722 0.962357068985217 0.999999985974598 BAX/ID3 2 GO:0002685 regulation of leukocyte migration 4/719 210/18722 0.962850186144008 0.999999985974598 HMGB1/MIF/C1QBP/DDT 4 GO:0002088 lens development in camera-type eye 1/719 84/18722 0.963005052102252 0.999999985974598 CDK4 1 GO:0009953 dorsal/ventral pattern formation 1/719 84/18722 0.963005052102252 0.999999985974598 MDFI 1 GO:0097061 dendritic spine organization 1/719 84/18722 0.963005052102252 0.999999985974598 CFL1 1 GO:1990138 neuron projection extension 3/719 172/18722 0.963392035329848 0.999999985974598 AURKA/HSP90AB1/HSP90AA1 3 GO:0019827 stem cell population maintenance 2/719 131/18722 0.963577426806475 0.999999985974598 TPT1/SMC3 2 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2/719 131/18722 0.963577426806475 0.999999985974598 CAV1/PIN1 2 GO:0051480 regulation of cytosolic calcium ion concentration 8/719 353/18722 0.963752868961333 0.999999985974598 HMGB1/CALM2/GSTO1/CALM1/CD24/YWHAE/CAV1/BAX 8 GO:0030100 regulation of endocytosis 4/719 211/18722 0.963839157426849 0.999999985974598 CALM1/ANXA2/AP2S1/CAV1 4 GO:0022409 positive regulation of cell-cell adhesion 6/719 284/18722 0.964011790000613 0.999999985974598 HMGB1/RPS3/CD24/HSPD1/CAV1/PNP 6 GO:0072659 protein localization to plasma membrane 6/719 284/18722 0.964011790000613 0.999999985974598 S100A10/ANXA2/KRT18/VAMP8/NSG1/ITGB1BP1 6 GO:0007204 positive regulation of cytosolic calcium ion concentration 7/719 319/18722 0.964012559955633 0.999999985974598 HMGB1/CALM2/GSTO1/CALM1/CD24/CAV1/BAX 7 GO:0008202 steroid metabolic process 7/719 319/18722 0.964012559955633 0.999999985974598 YWHAH/SOD1/COMT/FDPS/HINT2/AKR1B1/HSD17B10 7 GO:0030433 ubiquitin-dependent ERAD pathway 1/719 85/18722 0.964432209927044 0.999999985974598 CAV1 1 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 1/719 85/18722 0.964432209927044 0.999999985974598 CAV1 1 GO:0097006 regulation of plasma lipoprotein particle levels 1/719 85/18722 0.964432209927044 0.999999985974598 ANXA2 1 GO:0072175 epithelial tube formation 2/719 132/18722 0.964759744353148 0.999999985974598 PFN1/RPS7 2 GO:0035023 regulation of Rho protein signal transduction 1/719 86/18722 0.965804385763416 0.999999985974598 STMN1 1 GO:0045921 positive regulation of exocytosis 1/719 86/18722 0.965804385763416 0.999999985974598 VAMP8 1 GO:0003341 cilium movement 3/719 175/18722 0.966491594698103 0.999999985974598 SLIRP/CFAP20/MKKS 3 GO:0040013 negative regulation of locomotion 9/719 391/18722 0.966801986601606 0.999999985974598 HMGB1/GSTP1/MIF/IDH2/CSNK2B/APEX1/DDT/PIN1/ITGB1BP1 9 GO:0019915 lipid storage 1/719 87/18722 0.96712369498407 0.999999985974598 CAV1 1 GO:0150104 transport across blood-brain barrier 1/719 87/18722 0.96712369498407 0.999999985974598 SLC29A1 1 GO:2000177 regulation of neural precursor cell proliferation 1/719 87/18722 0.96712369498407 0.999999985974598 NAP1L1 1 GO:0002687 positive regulation of leukocyte migration 2/719 135/18722 0.968089473948981 0.999999985974598 HMGB1/C1QBP 2 GO:0042157 lipoprotein metabolic process 2/719 135/18722 0.968089473948981 0.999999985974598 DBI/ZDHHC12 2 GO:0007260 tyrosine phosphorylation of STAT protein 1/719 88/18722 0.968392171684174 0.999999985974598 CAV1 1 GO:0010232 vascular transport 1/719 88/18722 0.968392171684174 0.999999985974598 SLC29A1 1 GO:0030101 natural killer cell activation 1/719 88/18722 0.968392171684174 0.999999985974598 PRDX1 1 GO:0032103 positive regulation of response to external stimulus 10/719 427/18722 0.968448203160809 0.999999985974598 HMGB2/HMGB1/RPS19/PARK7/HSPD1/C1QBP/HSP90AA1/XRCC6/VAMP8/DDT 10 GO:1903305 regulation of regulated secretory pathway 2/719 136/18722 0.969130503952105 0.999999985974598 CALM1/VAMP8 2 GO:0002429 immune response-activating cell surface receptor signaling pathway 6/719 291/18722 0.969563051165117 0.999999985974598 RPS3/PHPT1/UBE2N/STOML2/HRAS/BAX 6 GO:0002757 immune response-activating signal transduction 6/719 291/18722 0.969563051165117 0.999999985974598 RPS3/PHPT1/UBE2N/STOML2/HRAS/BAX 6 GO:0043547 positive regulation of GTPase activity 5/719 255/18722 0.969750416608606 0.999999985974598 S100A10/EZH2/ECT2/PIN1/HRAS 5 GO:0008203 cholesterol metabolic process 2/719 137/18722 0.970138787549521 0.999999985974598 SOD1/FDPS 2 GO:0055123 digestive system development 2/719 137/18722 0.970138787549521 0.999999985974598 TYMS/CCNB1 2 GO:0090090 negative regulation of canonical Wnt signaling pathway 2/719 137/18722 0.970138787549521 0.999999985974598 RBX1/CAV1 2 GO:0023061 signal release 11/719 463/18722 0.970152059939437 0.999999985974598 PHPT1/CALM1/DYNLL1/PARK7/MPC2/UQCC2/ENY2/VAMP8/HADH/PNKD/ENSA 11 GO:0051251 positive regulation of lymphocyte activation 8/719 362/18722 0.970204173780904 0.999999985974598 HMGB1/RPS3/MIF/CD24/HSPD1/XRCC6/CAV1/PNP 8 GO:0001936 regulation of endothelial cell proliferation 3/719 179/18722 0.970240767530337 0.999999985974598 HMGB2/HMGB1/CAV1 3 GO:0010632 regulation of epithelial cell migration 6/719 292/18722 0.970288600647218 0.999999985974598 HMGB1/PFN1/ANXA3/CSNK2B/RAB25/ITGB1BP1 6 GO:0034976 response to endoplasmic reticulum stress 5/719 256/18722 0.970514036076612 0.999999985974598 PARK7/CAV1/CCND1/UFC1/BAX 5 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 5/719 256/18722 0.970514036076612 0.999999985974598 HSP90AB1/CSNK2B/CAV1/PARP1/PIN1 5 GO:0002028 regulation of sodium ion transport 1/719 90/18722 0.9707843761083 0.999999985974598 YWHAH 1 GO:0035278 miRNA mediated inhibition of translation 1/719 90/18722 0.9707843761083 0.999999985974598 EIF6 1 GO:0040033 negative regulation of translation, ncRNA-mediated 1/719 90/18722 0.9707843761083 0.999999985974598 EIF6 1 GO:0042475 odontogenesis of dentin-containing tooth 1/719 90/18722 0.9707843761083 0.999999985974598 BAX 1 GO:0070664 negative regulation of leukocyte proliferation 1/719 90/18722 0.9707843761083 0.999999985974598 GSTP1 1 GO:0097581 lamellipodium organization 1/719 90/18722 0.9707843761083 0.999999985974598 ARPC5 1 GO:0099175 regulation of postsynapse organization 1/719 90/18722 0.9707843761083 0.999999985974598 CFL1 1 GO:0007224 smoothened signaling pathway 2/719 138/18722 0.971115299897656 0.999999985974598 HSPB11/SSNA1 2 GO:0045582 positive regulation of T cell differentiation 1/719 91/18722 0.971911793110132 0.999999985974598 PNP 1 GO:0045974 regulation of translation, ncRNA-mediated 1/719 91/18722 0.971911793110132 0.999999985974598 EIF6 1 GO:0072080 nephron tubule development 1/719 91/18722 0.971911793110132 0.999999985974598 CD24 1 GO:0098661 inorganic anion transmembrane transport 1/719 91/18722 0.971911793110132 0.999999985974598 SLC25A3 1 GO:0008361 regulation of cell size 3/719 181/18722 0.97196314125503 0.999999985974598 NPM1/HSP90AB1/CDK4 3 GO:0045766 positive regulation of angiogenesis 3/719 181/18722 0.97196314125503 0.999999985974598 HMGB1/PKM/ANXA3 3 GO:1904018 positive regulation of vasculature development 3/719 181/18722 0.97196314125503 0.999999985974598 HMGB1/PKM/ANXA3 3 GO:0048638 regulation of developmental growth 7/719 330/18722 0.972007700056251 0.999999985974598 CDK1/CCNB1/SOD1/DUSP9/CDK4/MKKS/PIN1 7 GO:0019216 regulation of lipid metabolic process 7/719 331/18722 0.972647349812652 0.999999985974598 SOD1/EDF1/CAV1/STOML2/EIF6/CDK4/PHB2 7 GO:0045927 positive regulation of growth 5/719 259/18722 0.972699134066226 0.999999985974598 CDK1/CCNB1/DNPH1/MKKS/PIN1 5 GO:0050921 positive regulation of chemotaxis 2/719 141/18722 0.973863567538359 0.999999985974598 HMGB1/C1QBP 2 GO:1903038 negative regulation of leukocyte cell-cell adhesion 2/719 141/18722 0.973863567538359 0.999999985974598 HMGB1/PRDX2 2 GO:0106027 neuron projection organization 1/719 93/18722 0.974037954357976 0.999999985974598 CFL1 1 GO:0045785 positive regulation of cell adhesion 10/719 437/18722 0.974287838467441 0.999999985974598 HMGB1/S100A10/RPS3/CD24/ARL2/HSPD1/C1QBP/CAV1/PNP/ITGB1BP1 10 GO:0010720 positive regulation of cell development 6/719 298/18722 0.974318184994187 0.999999985974598 S100A10/AURKA/NAP1L1/C1QBP/FAIM/RHEB 6 GO:0007009 plasma membrane organization 2/719 142/18722 0.97472222593228 0.999999985974598 SOD1/CAV1 2 GO:0001738 morphogenesis of a polarized epithelium 1/719 94/18722 0.975039978665057 0.999999985974598 ACTG1 1 GO:0002042 cell migration involved in sprouting angiogenesis 1/719 94/18722 0.975039978665057 0.999999985974598 ITGB1BP1 1 GO:0048704 embryonic skeletal system morphogenesis 1/719 94/18722 0.975039978665057 0.999999985974598 MDFI 1 GO:0061326 renal tubule development 1/719 94/18722 0.975039978665057 0.999999985974598 CD24 1 GO:1903035 negative regulation of response to wounding 1/719 94/18722 0.975039978665057 0.999999985974598 ANXA2 1 GO:0002040 sprouting angiogenesis 3/719 185/18722 0.975128654617587 0.999999985974598 HMGB1/PKM/ITGB1BP1 3 GO:0007369 gastrulation 3/719 185/18722 0.975128654617587 0.999999985974598 RPS6/HSBP1/MKKS 3 GO:0003018 vascular process in circulatory system 5/719 263/18722 0.975379303500686 0.999999985974598 SOD1/CAV1/MKKS/SLC29A1/ITGB1BP1 5 GO:1903037 regulation of leukocyte cell-cell adhesion 7/719 336/18722 0.975649281999018 0.999999985974598 HMGB1/PRDX2/RPS3/CD24/HSPD1/CAV1/PNP 7 GO:0002443 leukocyte mediated immunity 10/719 440/18722 0.975838046678615 0.999999985974598 HMGB1/TUBB/TUBB4B/PRDX1/ANXA3/UNG/HSPD1/C1QBP/S100A13/VAMP8 10 GO:0008217 regulation of blood pressure 3/719 186/18722 0.97586531217193 0.999999985974598 SOD1/ADH5/MKKS 3 GO:0008593 regulation of Notch signaling pathway 1/719 95/18722 0.976003380819868 0.999999985974598 ITGB1BP1 1 GO:0045666 positive regulation of neuron differentiation 1/719 95/18722 0.976003380819868 0.999999985974598 ECT2 1 GO:0007612 learning 2/719 144/18722 0.976358525546315 0.999999985974598 VDAC1/COMT 2 GO:0010324 membrane invagination 2/719 144/18722 0.976358525546315 0.999999985974598 AURKB/SNX3 2 GO:0042472 inner ear morphogenesis 1/719 96/18722 0.976929647486026 0.999999985974598 SOD1 1 GO:0007269 neurotransmitter secretion 2/719 145/18722 0.977137793918384 0.999999985974598 CALM1/PNKD 2 GO:0099643 signal release from synapse 2/719 145/18722 0.977137793918384 0.999999985974598 CALM1/PNKD 2 GO:0048839 inner ear development 3/719 188/18722 0.977276897989169 0.999999985974598 CCNA2/SOD1/ANP32B 3 GO:0060070 canonical Wnt signaling pathway 6/719 303/18722 0.977284234782972 0.999999985974598 RPS12/RBX1/PPP1CA/CAV1/PIN1/RUVBL1 6 GO:0002697 regulation of immune effector process 7/719 339/18722 0.977301926949664 0.999999985974598 HMGB1/RPS19/HSPD1/C1QBP/VAMP8/PHB/PHB2 7 GO:0002696 positive regulation of leukocyte activation 9/719 409/18722 0.9773680835726 0.999999985974598 HMGB1/RPS3/MIF/CD24/HSPD1/XRCC6/CAV1/VAMP8/PNP 9 GO:0045444 fat cell differentiation 4/719 229/18722 0.977941040244181 0.999999985974598 ADIRF/CCND1/MKKS/BNIP3 4 GO:0071695 anatomical structure maturation 4/719 229/18722 0.977941040244181 0.999999985974598 TYMS/CCNB1/AURKA/AKR1B1 4 GO:0046578 regulation of Ras protein signal transduction 3/719 189/18722 0.977952899650941 0.999999985974598 STMN1/DYNLT1/HRAS 3 GO:0016197 endosomal transport 4/719 230/18722 0.978548262194692 0.999999985974598 VPS29/DPY30/SNX3/NSG1 4 GO:0045055 regulated exocytosis 4/719 230/18722 0.978548262194692 0.999999985974598 CALM1/ANXA3/S100A13/VAMP8 4 GO:0016331 morphogenesis of embryonic epithelium 2/719 147/18722 0.978622466287314 0.999999985974598 PFN1/RPS7 2 GO:0006650 glycerophospholipid metabolic process 6/719 306/18722 0.978908185545772 0.999999985974598 DBI/PRDX6/PGP/IMPA2/STOML2/PHB2 6 GO:0097530 granulocyte migration 2/719 148/18722 0.979329364196599 0.999999985974598 PPIA/C1QBP 2 GO:0000045 autophagosome assembly 1/719 99/18722 0.979499657037932 0.999999985974598 NSFL1C 1 GO:0007631 feeding behavior 1/719 99/18722 0.979499657037932 0.999999985974598 CFAP20 1 GO:0010717 regulation of epithelial to mesenchymal transition 1/719 99/18722 0.979499657037932 0.999999985974598 EZH2 1 GO:0021510 spinal cord development 1/719 99/18722 0.979499657037932 0.999999985974598 ACTL6A 1 GO:0031341 regulation of cell killing 1/719 99/18722 0.979499657037932 0.999999985974598 HSP90AB1 1 GO:0060291 long-term synaptic potentiation 1/719 99/18722 0.979499657037932 0.999999985974598 NSG1 1 GO:0060996 dendritic spine development 1/719 99/18722 0.979499657037932 0.999999985974598 CFL1 1 GO:0010594 regulation of endothelial cell migration 4/719 232/18722 0.979715789753765 0.999999985974598 HMGB1/ANXA3/CSNK2B/ITGB1BP1 4 GO:1905039 carboxylic acid transmembrane transport 2/719 149/18722 0.980013597384453 0.999999985974598 MPC2/SLC25A1 2 GO:0007160 cell-matrix adhesion 4/719 233/18722 0.980276837737129 0.999999985974598 S100A10/ACTG1/CDKN2A/ITGB1BP1 4 GO:0006641 triglyceride metabolic process 1/719 100/18722 0.980291137819209 0.999999985974598 CAV1 1 GO:0006664 glycolipid metabolic process 1/719 100/18722 0.980291137819209 0.999999985974598 BAX 1 GO:0019218 regulation of steroid metabolic process 1/719 100/18722 0.980291137819209 0.999999985974598 SOD1 1 GO:0045807 positive regulation of endocytosis 1/719 100/18722 0.980291137819209 0.999999985974598 ANXA2 1 GO:0060079 excitatory postsynaptic potential 1/719 100/18722 0.980291137819209 0.999999985974598 SLC29A1 1 GO:1903825 organic acid transmembrane transport 2/719 150/18722 0.980675860864332 0.999999985974598 MPC2/SLC25A1 2 GO:0048588 developmental cell growth 4/719 234/18722 0.980823224090828 0.999999985974598 AURKA/HSP90AB1/HSP90AA1/PIN1 4 GO:1903509 liposaccharide metabolic process 1/719 101/18722 0.981052101835319 0.999999985974598 BAX 1 GO:0050777 negative regulation of immune response 3/719 194/18722 0.981055365021745 0.999999985974598 RPS19/C1QBP/PSMB4 3 GO:0048754 branching morphogenesis of an epithelial tube 2/719 151/18722 0.981316829792438 0.999999985974598 PPP1CA/PHB2 2 GO:0045833 negative regulation of lipid metabolic process 1/719 102/18722 0.981783724131673 0.999999985974598 SOD1 1 GO:0016125 sterol metabolic process 2/719 152/18722 0.981937159965146 0.999999985974598 SOD1/FDPS 2 GO:0021915 neural tube development 2/719 152/18722 0.981937159965146 0.999999985974598 PFN1/RPS7 2 GO:0071674 mononuclear cell migration 3/719 196/18722 0.982175789456926 0.999999985974598 HMGB1/RPS19/C1QBP 3 GO:0050867 positive regulation of cell activation 9/719 420/18722 0.982208696426365 0.999999985974598 HMGB1/RPS3/MIF/CD24/HSPD1/XRCC6/CAV1/VAMP8/PNP 9 GO:0019233 sensory perception of pain 1/719 103/18722 0.982487134569338 0.999999985974598 COMT 1 GO:1905037 autophagosome organization 1/719 103/18722 0.982487134569338 0.999999985974598 NSFL1C 1 GO:0002449 lymphocyte mediated immunity 7/719 350/18722 0.982516140646892 0.999999985974598 HMGB1/TUBB/TUBB4B/PRDX1/UNG/HSPD1/C1QBP 7 GO:0042594 response to starvation 3/719 197/18722 0.982711985308205 0.999999985974598 HNRNPA1/PAGE4/COMT 3 GO:0006892 post-Golgi vesicle-mediated transport 1/719 104/18722 0.983163419560188 0.999999985974598 KRT18 1 GO:1903076 regulation of protein localization to plasma membrane 1/719 104/18722 0.983163419560188 0.999999985974598 VAMP8 1 GO:0016079 synaptic vesicle exocytosis 1/719 105/18722 0.983813623735515 0.999999985974598 CALM1 1 GO:0043542 endothelial cell migration 5/719 279/18722 0.983833349454165 0.999999985974598 HMGB1/ANXA3/CSNK2B/ID1/ITGB1BP1 5 GO:0009267 cellular response to starvation 2/719 156/18722 0.984224558545724 0.999999985974598 HNRNPA1/COMT 2 GO:0099003 vesicle-mediated transport in synapse 3/719 200/18722 0.984229607291264 0.999999985974598 CALM1/ACTG1/NSG1 3 GO:0099565 chemical synaptic transmission, postsynaptic 1/719 106/18722 0.984438751550639 0.999999985974598 SLC29A1 1 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 7/719 355/18722 0.984497934872856 0.999999985974598 HSP90AB1/CSNK2B/CAV1/SUB1/PARP1/PIN1/ID1 7 GO:0001837 epithelial to mesenchymal transition 2/719 157/18722 0.984750887993175 0.999999985974598 HNRNPAB/EZH2 2 GO:0051250 negative regulation of lymphocyte activation 2/719 157/18722 0.984750887993175 0.999999985974598 HMGB1/PRDX2 2 GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1/719 107/18722 0.985039768827986 0.999999985974598 HSPD1 1 GO:0007229 integrin-mediated signaling pathway 1/719 107/18722 0.985039768827986 0.999999985974598 ITGB1BP1 1 GO:0036503 ERAD pathway 1/719 107/18722 0.985039768827986 0.999999985974598 CAV1 1 GO:0042303 molting cycle 1/719 107/18722 0.985039768827986 0.999999985974598 SNRPE 1 GO:0042633 hair cycle 1/719 107/18722 0.985039768827986 0.999999985974598 SNRPE 1 GO:1903532 positive regulation of secretion by cell 5/719 282/18722 0.985078010466493 0.999999985974598 PPIA/PHPT1/DYNLL1/MPC2/VAMP8 5 GO:0009913 epidermal cell differentiation 3/719 202/18722 0.985169596169703 0.999999985974598 SOD1/EZH2/KRT10 3 GO:0019722 calcium-mediated signaling 3/719 202/18722 0.985169596169703 0.999999985974598 CALM2/GSTO1/CALM1 3 GO:0001818 negative regulation of cytokine production 7/719 357/18722 0.985230455785665 0.999999985974598 HMGB1/GSTP1/HSP90AB1/CD24/C1QBP/EZH2/NUTF2 7 GO:0010631 epithelial cell migration 7/719 357/18722 0.985230455785665 0.999999985974598 HMGB1/PFN1/ANXA3/CSNK2B/RAB25/ID1/ITGB1BP1 7 GO:0006958 complement activation, classical pathway 1/719 108/18722 0.985617604240969 0.999999985974598 C1QBP 1 GO:0098659 inorganic cation import across plasma membrane 1/719 108/18722 0.985617604240969 0.999999985974598 ISCU 1 GO:0099587 inorganic ion import across plasma membrane 1/719 108/18722 0.985617604240969 0.999999985974598 ISCU 1 GO:0072009 nephron epithelium development 1/719 109/18722 0.986173150740955 0.999999985974598 CD24 1 GO:0090132 epithelium migration 7/719 360/18722 0.986268968497213 0.999999985974598 HMGB1/PFN1/ANXA3/CSNK2B/RAB25/ID1/ITGB1BP1 7 GO:0051650 establishment of vesicle localization 2/719 161/18722 0.986690624270696 0.999999985974598 MKKS/AP1M2 2 GO:0002698 negative regulation of immune effector process 1/719 110/18722 0.986707266929493 0.999999985974598 RPS19 1 GO:0030317 flagellated sperm motility 1/719 110/18722 0.986707266929493 0.999999985974598 SLIRP 1 GO:0048259 regulation of receptor-mediated endocytosis 1/719 110/18722 0.986707266929493 0.999999985974598 ANXA2 1 GO:0097722 sperm motility 1/719 110/18722 0.986707266929493 0.999999985974598 SLIRP 1 GO:0048863 stem cell differentiation 3/719 206/18722 0.986891039770477 0.999999985974598 KRT18/METTL5/PSMD11 3 GO:0060562 epithelial tube morphogenesis 6/719 325/18722 0.986932404739402 0.999999985974598 PFN1/RPS7/PPP1CA/CSNK2B/PHB2/MKKS 6 GO:0002683 negative regulation of immune system process 9/719 434/18722 0.98699092386622 0.999999985974598 HMGB1/PRDX2/RPS19/MIF/PHPT1/NME1/C1QBP/DDT/PSMB4 9 GO:0015718 monocarboxylic acid transport 1/719 111/18722 0.987220778377897 0.999999985974598 MPC2 1 GO:0031589 cell-substrate adhesion 7/719 363/18722 0.987238997937225 0.999999985974598 S100A10/ACTG1/ARL2/C1QBP/CDKN2A/ID1/ITGB1BP1 7 GO:0016064 immunoglobulin mediated immune response 3/719 207/18722 0.987290454973613 0.999999985974598 UNG/HSPD1/C1QBP 3 GO:0002821 positive regulation of adaptive immune response 1/719 112/18722 0.987714478896208 0.999999985974598 HSPD1 1 GO:0019221 cytokine-mediated signaling pathway 10/719 472/18722 0.987816867812623 0.999999985974598 GSTP1/KRT8/KRT18/HSP90AB1/CD24/EIF5A/CSNK2B/CAV1/TXNDC17/MKKS 10 GO:0090130 tissue migration 7/719 365/18722 0.987849680110742 0.999999985974598 HMGB1/PFN1/ANXA3/CSNK2B/RAB25/ID1/ITGB1BP1 7 GO:0002700 regulation of production of molecular mediator of immune response 2/719 164/18722 0.987985645325362 0.999999985974598 PHB/PHB2 2 GO:0050680 negative regulation of epithelial cell proliferation 2/719 164/18722 0.987985645325362 0.999999985974598 CAV1/PHB2 2 GO:0050806 positive regulation of synaptic transmission 2/719 164/18722 0.987985645325362 0.999999985974598 NSG1/ZDHHC12 2 GO:0001578 microtubule bundle formation 1/719 113/18722 0.988189131753469 0.999999985974598 PRC1 1 GO:0002708 positive regulation of lymphocyte mediated immunity 1/719 113/18722 0.988189131753469 0.999999985974598 HSPD1 1 GO:0031623 receptor internalization 1/719 113/18722 0.988189131753469 0.999999985974598 CAV1 1 GO:0032635 interleukin-6 production 2/719 165/18722 0.988389390576959 0.999999985974598 HMGB1/HSPD1 2 GO:0032675 regulation of interleukin-6 production 2/719 165/18722 0.988389390576959 0.999999985974598 HMGB1/HSPD1 2 GO:0019724 B cell mediated immunity 3/719 210/18722 0.988419790037803 0.999999985974598 UNG/HSPD1/C1QBP 3 GO:0061448 connective tissue development 4/719 252/18722 0.988518826997254 0.999999985974598 TYMS/UBB/CDK4/MKKS 4 GO:0002244 hematopoietic progenitor cell differentiation 1/719 114/18722 0.988645470851177 0.999999985974598 TOP2A 1 GO:0050807 regulation of synapse organization 3/719 211/18722 0.988774318392769 0.999999985974598 TUBB/CDC20/CFL1 3 GO:0030307 positive regulation of cell growth 2/719 166/18722 0.988779902776879 0.999999985974598 DNPH1/PIN1 2 GO:0001822 kidney development 5/719 293/18722 0.988911525240745 0.999999985974598 CD24/HSPB11/AKR1B1/BAX/ID3 5 GO:0042471 ear morphogenesis 1/719 115/18722 0.989084201851715 0.999999985974598 SOD1 1 GO:0090630 activation of GTPase activity 1/719 115/18722 0.989084201851715 0.999999985974598 ECT2 1 GO:0051960 regulation of nervous system development 9/719 443/18722 0.989403266931568 0.999999985974598 HMGB2/YWHAH/DYNLT1/IDH2/NAP1L1/EZH2/FAIM/RHEB/ID1 9 GO:0043583 ear development 3/719 213/18722 0.989452312440051 0.999999985974598 CCNA2/SOD1/ANP32B 3 GO:0030326 embryonic limb morphogenesis 1/719 116/18722 0.989506003263475 0.999999985974598 BAX 1 GO:0035113 embryonic appendage morphogenesis 1/719 116/18722 0.989506003263475 0.999999985974598 BAX 1 GO:0007159 leukocyte cell-cell adhesion 7/719 371/18722 0.98952157860525 0.999999985974598 HMGB1/PRDX2/RPS3/CD24/HSPD1/CAV1/PNP 7 GO:0002706 regulation of lymphocyte mediated immunity 2/719 168/18722 0.989522891538735 0.999999985974598 HMGB1/HSPD1 2 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2/719 168/18722 0.989522891538735 0.999999985974598 HMGB1/HSPD1 2 GO:0016482 cytosolic transport 2/719 168/18722 0.989522891538735 0.999999985974598 VPS29/SNX3 2 GO:0090596 sensory organ morphogenesis 4/719 256/18722 0.98977409732529 0.999999985974598 SOD1/HMGN1/C12orf57/BAX 4 GO:0031669 cellular response to nutrient levels 3/719 215/18722 0.990090800851302 0.999999985974598 HNRNPA1/COMT/TXN2 3 GO:0007259 receptor signaling pathway via JAK-STAT 2/719 170/18722 0.990217814646217 0.999999985974598 CAV1/AKR1B1 2 GO:0009612 response to mechanical stimulus 3/719 216/18722 0.990395919494205 0.999999985974598 CCNB1/MKKS/BNIP3 3 GO:0001655 urogenital system development 6/719 338/18722 0.990661574510707 0.999999985974598 HELLS/CD24/HSPB11/AKR1B1/BAX/ID3 6 GO:0016050 vesicle organization 5/719 300/18722 0.990843613343893 0.999999985974598 S100A10/ANXA2/CAV1/VAMP8/SNX3 5 GO:0007219 Notch signaling pathway 2/719 172/18722 0.990867684364561 0.999999985974598 KRT19/ITGB1BP1 2 GO:0042445 hormone metabolic process 3/719 218/18722 0.990979221516181 0.999999985974598 COMT/AKR1B1/HSD17B10 3 GO:0050803 regulation of synapse structure or activity 3/719 218/18722 0.990979221516181 0.999999985974598 TUBB/CDC20/CFL1 3 GO:0002761 regulation of myeloid leukocyte differentiation 1/719 120/18722 0.991036590127163 0.999999985974598 NME1 1 GO:0071805 potassium ion transmembrane transport 3/719 219/18722 0.991257910675313 0.999999985974598 YWHAE/CAV1/SUMO1 3 GO:0072001 renal system development 5/719 302/18722 0.991334010367117 0.999999985974598 CD24/HSPB11/AKR1B1/BAX/ID3 5 GO:0001704 formation of primary germ layer 1/719 121/18722 0.991383041675306 0.999999985974598 HSBP1 1 GO:0002455 humoral immune response mediated by circulating immunoglobulin 1/719 121/18722 0.991383041675306 0.999999985974598 C1QBP 1 GO:0003206 cardiac chamber morphogenesis 1/719 121/18722 0.991383041675306 0.999999985974598 LY6E 1 GO:0048706 embryonic skeletal system development 1/719 121/18722 0.991383041675306 0.999999985974598 MDFI 1 GO:0048771 tissue remodeling 2/719 175/18722 0.991764162044419 0.999999985974598 CAV1/BAX 2 GO:0003231 cardiac ventricle development 1/719 123/18722 0.992036341113825 0.999999985974598 LY6E 1 GO:0034329 cell junction assembly 8/719 420/18722 0.99222486213751 0.999999985974598 S100A10/ACTG1/ARL2/CAV1/ECT2/RHOC/ITGB1BP1/ZDHHC12 8 GO:0051648 vesicle localization 2/719 177/18722 0.992313418550727 0.999999985974598 MKKS/AP1M2 2 GO:0007368 determination of left/right symmetry 1/719 124/18722 0.992344200178246 0.999999985974598 MKKS 1 GO:2000027 regulation of animal organ morphogenesis 1/719 125/18722 0.992640173942728 0.999999985974598 PHB2 1 GO:0002440 production of molecular mediator of immune response 5/719 308/18722 0.992659725969142 0.999999985974598 UNG/CTNNBL1/HSPD1/PHB/PHB2 5 GO:0050769 positive regulation of neurogenesis 3/719 225/18722 0.992763490772759 0.999999985974598 NAP1L1/FAIM/RHEB 3 GO:0007626 locomotory behavior 2/719 179/18722 0.992826809623897 0.999999985974598 SOD1/PARK7 2 GO:0002703 regulation of leukocyte mediated immunity 3/719 226/18722 0.992988727097272 0.999999985974598 HMGB1/HSPD1/VAMP8 3 GO:0051047 positive regulation of secretion 5/719 310/18722 0.993056956131889 0.999999985974598 PPIA/PHPT1/DYNLL1/MPC2/VAMP8 5 GO:0007033 vacuole organization 2/719 180/18722 0.993070772660532 0.999999985974598 ANXA2/NSFL1C 2 GO:0098657 import into cell 3/719 227/18722 0.99320717747121 0.999999985974598 PARK7/SLC29A1/ISCU 3 GO:0097696 receptor signaling pathway via STAT 2/719 181/18722 0.993306612117576 0.999999985974598 CAV1/AKR1B1 2 GO:0099504 synaptic vesicle cycle 2/719 181/18722 0.993306612117576 0.999999985974598 CALM1/ACTG1 2 GO:0048568 embryonic organ development 8/719 427/18722 0.993444739807479 0.999999985974598 RPL10/KRT19/SOD1/KRT8/PHLDA2/MDFI/MKKS/ID3 8 GO:0006639 acylglycerol metabolic process 1/719 128/18722 0.993461278228948 0.999999985974598 CAV1 1 GO:0061138 morphogenesis of a branching epithelium 2/719 182/18722 0.993534590966047 0.999999985974598 PPP1CA/PHB2 2 GO:0031346 positive regulation of cell projection organization 6/719 353/18722 0.993712534092274 0.999999985974598 PFN1/NME1/DYNLT1/EZH2/SNX3/HRAS 6 GO:0006638 neutral lipid metabolic process 1/719 129/18722 0.99371412005714 0.999999985974598 CAV1 1 GO:0002819 regulation of adaptive immune response 2/719 183/18722 0.993754963997618 0.999999985974598 HMGB1/HSPD1 2 GO:0046486 glycerolipid metabolic process 7/719 392/18722 0.99382364582982 0.999999985974598 DBI/PRDX6/PGP/IMPA2/CAV1/STOML2/PHB2 7 GO:0030534 adult behavior 1/719 130/18722 0.993957197972426 0.999999985974598 PARK7 1 GO:0006661 phosphatidylinositol biosynthetic process 1/719 131/18722 0.994190888519856 0.999999985974598 IMPA2 1 GO:0050853 B cell receptor signaling pathway 1/719 131/18722 0.994190888519856 0.999999985974598 BAX 1 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6/719 356/18722 0.994196413551461 0.999999985974598 HMGB1/UNG/HSPD1/C1QBP/PHB/HRAS 6 GO:0031345 negative regulation of cell projection organization 2/719 186/18722 0.994372878397618 0.999999985974598 YWHAH/ID1 2 GO:1902115 regulation of organelle assembly 2/719 186/18722 0.994372878397618 0.999999985974598 NPM1/VDAC3 2 GO:0045667 regulation of osteoblast differentiation 1/719 132/18722 0.994415553742503 0.999999985974598 ID3 1 GO:0060560 developmental growth involved in morphogenesis 3/719 234/18722 0.994562107567137 0.999999985974598 AURKA/HSP90AB1/HSP90AA1 3 GO:0002695 negative regulation of leukocyte activation 2/719 187/18722 0.994565220733686 0.999999985974598 HMGB1/PRDX2 2 GO:0009855 determination of bilateral symmetry 1/719 133/18722 0.994631541739229 0.999999985974598 MKKS 1 GO:0002705 positive regulation of leukocyte mediated immunity 1/719 134/18722 0.994839187201034 0.999999985974598 HSPD1 1 GO:0009799 specification of symmetry 1/719 134/18722 0.994839187201034 0.999999985974598 MKKS 1 GO:0042552 myelination 1/719 134/18722 0.994839187201034 0.999999985974598 SOD1 1 GO:0001667 ameboidal-type cell migration 9/719 475/18722 0.995004989802099 0.999999985974598 HMGB1/PFN1/PDLIM1/ANXA3/C1QBP/CSNK2B/RAB25/ID1/ITGB1BP1 9 GO:0009581 detection of external stimulus 1/719 135/18722 0.995038811926796 0.999999985974598 MKKS 1 GO:0051216 cartilage development 2/719 190/18722 0.995104404851273 0.999999985974598 TYMS/MKKS 2 GO:0050804 modulation of chemical synaptic transmission 8/719 439/18722 0.995126373044359 0.999999985974598 RPL22/CALM1/YWHAH/CDC20/PNKD/NSG1/HRAS/ZDHHC12 8 GO:0007272 ensheathment of neurons 1/719 136/18722 0.995230725319201 0.999999985974598 SOD1 1 GO:0008366 axon ensheathment 1/719 136/18722 0.995230725319201 0.999999985974598 SOD1 1 GO:0072073 kidney epithelium development 1/719 136/18722 0.995230725319201 0.999999985974598 CD24 1 GO:0099024 plasma membrane invagination 1/719 136/18722 0.995230725319201 0.999999985974598 AURKB 1 GO:0099177 regulation of trans-synaptic signaling 8/719 440/18722 0.995246310449311 0.999999985974598 RPL22/CALM1/YWHAH/CDC20/PNKD/NSG1/HRAS/ZDHHC12 8 GO:0008544 epidermis development 5/719 324/18722 0.995315091963071 0.999999985974598 YBX1/SOD1/EZH2/KRT10/TFDP1 5 GO:0007586 digestion 1/719 137/18722 0.995415224861625 0.999999985974598 PIR 1 GO:0060078 regulation of postsynaptic membrane potential 1/719 137/18722 0.995415224861625 0.999999985974598 SLC29A1 1 GO:0015850 organic hydroxy compound transport 4/719 284/18722 0.99552701059186 0.999999985974598 LY6E/PARK7/ANXA2/CAV1 4 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 2/719 193/18722 0.995591040850521 0.999999985974598 MIF/CD24 2 GO:0009582 detection of abiotic stimulus 1/719 138/18722 0.99559259657669 0.999999985974598 MKKS 1 GO:0035107 appendage morphogenesis 1/719 138/18722 0.99559259657669 0.999999985974598 BAX 1 GO:0035108 limb morphogenesis 1/719 138/18722 0.99559259657669 0.999999985974598 BAX 1 GO:0006813 potassium ion transport 3/719 241/18722 0.995653435089612 0.999999985974598 YWHAE/CAV1/SUMO1 3 GO:0007517 muscle organ development 5/719 327/18722 0.995697575909769 0.999999985974598 LY6E/UQCC2/MYL6/CAV1/ID3 5 GO:0030216 keratinocyte differentiation 1/719 139/18722 0.995763115467207 0.999999985974598 KRT10 1 GO:0045598 regulation of fat cell differentiation 1/719 139/18722 0.995763115467207 0.999999985974598 ADIRF 1 GO:0044782 cilium organization 6/719 368/18722 0.995800053681703 0.999999985974598 DYNLL1/HSPB11/VDAC3/CFAP20/MKKS/SSNA1 6 GO:0010975 regulation of neuron projection development 8/719 445/18722 0.995805185167033 0.999999985974598 YWHAH/CDC20/NME1/CFL1/DYNLT1/EZH2/SNX3/ID1 8 GO:0050900 leukocyte migration 6/719 369/18722 0.995912618797136 0.999999985974598 HMGB1/PPIA/RPS19/MIF/C1QBP/DDT 6 GO:0001763 morphogenesis of a branching structure 2/719 196/18722 0.996030133028454 0.999999985974598 PPP1CA/PHB2 2 GO:0022408 negative regulation of cell-cell adhesion 2/719 196/18722 0.996030133028454 0.999999985974598 HMGB1/PRDX2 2 GO:0045664 regulation of neuron differentiation 2/719 196/18722 0.996030133028454 0.999999985974598 YWHAH/ECT2 2 GO:0072006 nephron development 1/719 142/18722 0.996236148712924 0.999999985974598 CD24 1 GO:0070555 response to interleukin-1 1/719 143/18722 0.996381800439265 0.999999985974598 TAF9 1 GO:0014065 phosphatidylinositol 3-kinase signaling 1/719 144/18722 0.996521823340614 0.999999985974598 C1QBP 1 GO:0031644 regulation of nervous system process 1/719 144/18722 0.996521823340614 0.999999985974598 COMT 1 GO:0017157 regulation of exocytosis 2/719 202/18722 0.996783434677859 0.999999985974598 CALM1/VAMP8 2 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 1/719 146/18722 0.996785843251745 0.999999985974598 GNAS 1 GO:0048193 Golgi vesicle transport 4/719 296/18722 0.99688680334704 0.999999985974598 KRT18/TRAPPC1/COPE/SNX3 4 GO:0050890 cognition 4/719 296/18722 0.99688680334704 0.999999985974598 FEN1/VDAC1/COMT/C12orf57 4 GO:0008654 phospholipid biosynthetic process 3/719 253/18722 0.997049368267473 0.999999985974598 FDPS/IMPA2/ISYNA1 3 GO:0045834 positive regulation of lipid metabolic process 1/719 149/18722 0.997144822470512 0.999999985974598 STOML2 1 GO:0007611 learning or memory 3/719 255/18722 0.997234933289529 0.999999985974598 FEN1/VDAC1/COMT 3 GO:0055067 monovalent inorganic cation homeostasis 1/719 151/18722 0.997361609231656 0.999999985974598 COMT 1 GO:0051056 regulation of small GTPase mediated signal transduction 4/719 302/18722 0.997407058338675 0.999999985974598 STMN1/DYNLT1/ECT2/HRAS 4 GO:0050808 synapse organization 7/719 426/18722 0.997457414812262 0.999999985974598 TUBB/PFN1/CDC20/ACTG1/CFL1/PIN1/ZDHHC12 7 GO:0050871 positive regulation of B cell activation 1/719 152/18722 0.997463757902295 0.999999985974598 MIF 1 GO:0007162 negative regulation of cell adhesion 4/719 303/18722 0.997485149488935 0.999999985974598 HMGB1/PRDX2/CDKN2A/ITGB1BP1 4 GO:0050866 negative regulation of cell activation 2/719 210/18722 0.997573247369916 0.999999985974598 HMGB1/PRDX2 2 GO:0006665 sphingolipid metabolic process 1/719 155/18722 0.997747110870677 0.999999985974598 BAX 1 GO:0042742 defense response to bacterium 5/719 350/18722 0.997781813314884 0.999999985974598 HMGB2/RPS19/RPL30/ANXA3/ROMO1 5 GO:0001764 neuron migration 1/719 156/18722 0.997834353143741 0.999999985974598 BAX 1 GO:0006909 phagocytosis 4/719 308/18722 0.997842648698795 0.999999985974598 HMGB1/SOD1/ANXA3/SNX3 4 GO:0043588 skin development 3/719 263/18722 0.99786988787815 0.999999985974598 STMN1/PTGES3/KRT10 3 GO:0006887 exocytosis 5/719 352/18722 0.997907582239858 0.999999985974598 CALM1/ANXA3/S100A13/VAMP8/RAB25 5 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 3/719 264/18722 0.997938476015118 0.999999985974598 MIF/CD24/CAV1 3 GO:0015711 organic anion transport 5/719 354/18722 0.998026450736334 0.999999985974598 SLC25A5/SLC25A6/MPC2/SLC29A1/SLC25A1 5 GO:0046488 phosphatidylinositol metabolic process 1/719 159/18722 0.998076352712352 0.999999985974598 IMPA2 1 GO:0006869 lipid transport 6/719 398/18722 0.998166194138183 0.999999985974598 DBI/ANXA2/PRELID1/TRIAP1/CAV1/NME4 6 GO:0003205 cardiac chamber development 1/719 161/18722 0.998222487753642 0.999999985974598 LY6E 1 GO:0051962 positive regulation of nervous system development 3/719 272/18722 0.99841481296109 0.999999985974598 NAP1L1/FAIM/RHEB 3 GO:0010876 lipid localization 7/719 448/18722 0.998595053246946 0.999999985974598 DBI/ANXA2/PRELID1/TRIAP1/CAV1/STOML2/NME4 7 GO:0022407 regulation of cell-cell adhesion 7/719 448/18722 0.998595053246946 0.999999985974598 HMGB1/PRDX2/RPS3/CD24/HSPD1/CAV1/PNP 7 GO:0001503 ossification 6/719 408/18722 0.998617045682444 0.999999985974598 RPS15/HSPE1/ALYREF/PHB/FBL/ID3 6 GO:0031214 biomineral tissue development 1/719 169/18722 0.998704243168346 0.999999985974598 ITGB1BP1 1 GO:0110148 biomineralization 1/719 171/18722 0.998802730831427 0.999999985974598 ITGB1BP1 1 GO:0048736 appendage development 1/719 172/18722 0.998849134611935 0.999999985974598 BAX 1 GO:0060173 limb development 1/719 172/18722 0.998849134611935 0.999999985974598 BAX 1 GO:0048562 embryonic organ morphogenesis 3/719 285/18722 0.998969090198115 0.999999985974598 SOD1/MDFI/MKKS 3 GO:0048762 mesenchymal cell differentiation 2/719 236/18722 0.999037052237701 0.999999985974598 HNRNPAB/EZH2 2 GO:0098739 import across plasma membrane 1/719 177/18722 0.99905556077265 0.999999985974598 ISCU 1 GO:0035725 sodium ion transmembrane transport 1/719 178/18722 0.999092177208588 0.999999985974598 YWHAH 1 GO:0048015 phosphatidylinositol-mediated signaling 1/719 178/18722 0.999092177208588 0.999999985974598 C1QBP 1 GO:0060271 cilium assembly 4/719 337/18722 0.999125295448506 0.999999985974598 DYNLL1/VDAC3/CFAP20/MKKS 4 GO:0007416 synapse assembly 1/719 179/18722 0.999127375902884 0.999999985974598 ZDHHC12 1 GO:0061564 axon development 7/719 467/18722 0.999167364597448 0.999999985974598 STMN1/RPL24/DHFR/DYNLT1/HSP90AB1/HSP90AA1/C12orf57 7 GO:0048017 inositol lipid-mediated signaling 1/719 182/18722 0.999225003229734 0.999999985974598 C1QBP 1 GO:0003007 heart morphogenesis 2/719 246/18722 0.99932727103376 0.999999985974598 LY6E/MKKS 2 GO:1901342 regulation of vasculature development 4/719 348/18722 0.999382357057037 0.999999985974598 HMGB1/PKM/ANXA3/ID1 4 GO:0090287 regulation of cellular response to growth factor stimulus 3/719 304/18722 0.999454042089518 0.999999985974598 HSP90AB1/CAV1/PIN1 3 GO:0019932 second-messenger-mediated signaling 3/719 312/18722 0.999583181844513 0.999999985974598 CALM2/GSTO1/CALM1 3 GO:0050864 regulation of B cell activation 1/719 198/18722 0.999588524611429 0.999999985974598 MIF 1 GO:0009952 anterior/posterior pattern specification 1/719 201/18722 0.999634604966074 0.999999985974598 AURKA 1 GO:0006643 membrane lipid metabolic process 1/719 203/18722 0.9996624248857 0.999999985974598 BAX 1 GO:0007409 axonogenesis 5/719 418/18722 0.999712809856668 0.999999985974598 STMN1/RPL24/HSP90AB1/HSP90AA1/C12orf57 5 GO:0018108 peptidyl-tyrosine phosphorylation 4/719 375/18722 0.999740136686108 0.999999985974598 PBK/MIF/CD24/CAV1 4 GO:0046942 carboxylic acid transport 2/719 273/18722 0.999746506448857 0.999999985974598 MPC2/SLC25A1 2 GO:0046474 glycerophospholipid biosynthetic process 1/719 211/18722 0.999754097096122 0.999999985974598 IMPA2 1 GO:0018212 peptidyl-tyrosine modification 4/719 378/18722 0.999764195750063 0.999999985974598 PBK/MIF/CD24/CAV1 4 GO:0003002 regionalization 3/719 331/18722 0.999781511840357 0.999999985974598 AURKA/HSPB11/MDFI 3 GO:0007601 visual perception 1/719 215/18722 0.999790136203878 0.999999985974598 MKKS 1 GO:0050953 sensory perception of light stimulus 1/719 219/18722 0.999820899740258 0.999999985974598 MKKS 1 GO:0048705 skeletal system morphogenesis 1/719 220/18722 0.99982785931907 0.999999985974598 MDFI 1 GO:0045765 regulation of angiogenesis 3/719 342/18722 0.999850124522655 0.999999985974598 HMGB1/PKM/ANXA3 3 GO:0006486 protein glycosylation 1/719 226/18722 0.999864297643571 0.999999985974598 OST4 1 GO:0043413 macromolecule glycosylation 1/719 226/18722 0.999864297643571 0.999999985974598 OST4 1 GO:0060485 mesenchyme development 2/719 291/18722 0.999868485774106 0.999999985974598 HNRNPAB/EZH2 2 GO:0007411 axon guidance 1/719 227/18722 0.999869572837898 0.999999985974598 RPL24 1 GO:0097485 neuron projection guidance 1/719 228/18722 0.999874643242308 0.999999985974598 RPL24 1 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 1/719 233/18722 0.999897190787908 0.999999985974598 GNAS 1 GO:0030198 extracellular matrix organization 2/719 301/18722 0.999908822155879 0.999999985974598 ANXA2/CAV1 2 GO:0043062 extracellular structure organization 2/719 302/18722 0.999912107294663 0.999999985974598 ANXA2/CAV1 2 GO:0015849 organic acid transport 2/719 303/18722 0.999915275048402 0.999999985974598 MPC2/SLC25A1 2 GO:0045229 external encapsulating structure organization 2/719 304/18722 0.999918329571309 0.999999985974598 ANXA2/CAV1 2 GO:0070085 glycosylation 1/719 240/18722 0.999922119253642 0.999999985974598 OST4 1 GO:0006814 sodium ion transport 1/719 245/18722 0.999936135819859 0.999999985974598 YWHAH 1 GO:0045017 glycerolipid biosynthetic process 1/719 252/18722 0.999951630065281 0.999999985974598 IMPA2 1 GO:0007389 pattern specification process 4/719 436/18722 0.999965139205722 0.999999985974598 AURKA/HSPB11/MDFI/MKKS 4 GO:0009100 glycoprotein metabolic process 2/719 387/18722 0.999996257710448 0.999999985974598 PARK7/OST4 2 GO:0009101 glycoprotein biosynthetic process 1/719 317/18722 0.999996354768381 0.999999985974598 OST4 1 GO:0007608 sensory perception of smell 1/719 456/18722 0.999999985974598 0.999999985974598 MKKS 1