ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	Count
GO:0003735	structural constituent of ribosome	44/443	182/18367	1.41134457503776e-31	8.97615149724013e-29	RPS21/RPL18/RPS14/RPS29/RPS12/RPS27/RPLP1/RPL37/RPS28/RPL37A/RPS16/RPS23/RPS18/RPLP2/RPL23/RPS5/RPS7/RPS27A/RPL34/RPL8/RPLP0/RPL10A/RPS19/RPS25/RPL27A/RPL36/RPL23A/RPSA/RPL31/RPS17/RPL7A/RPS3/MRPS34/RPS26/MRPS33/MRPL27/MRPS15/MRPL20/MRPL52/MRPL4/MRPL21/MRPL57/MRPL36/RPS4Y1	44
GO:0009055	electron transfer activity	35/443	126/18367	1.45148056741231e-27	4.61570820437114e-25	COX6A1/DEGS1/NDUFB7/NDUFB10/NDUFC2/NDUFB9/GLDC/UQCR10/NDUFS6/CYB5A/COX5B/NDUFA13/NDUFS8/NDUFA4/NDUFB2/ADH5/COX7A2/AKR1B1/NDUFS5/NDUFB4/NDUFA1/COX4I1/NDUFV2/ETFA/ASPH/COX5A/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/CYC1/NDUFB8/NDUFA3/UQCRC1	35
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	28/443	72/18367	6.20254483599744e-27	1.31493950523146e-24	COX6A1/NDUFB7/NDUFB10/NDUFC2/NDUFB9/UQCR10/NDUFS6/CYB5A/COX5B/NDUFA13/NDUFS8/NDUFA4/NDUFB2/NDUFS5/NDUFB4/NDUFA1/COX4I1/NDUFV2/COX5A/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/CYC1/NDUFB8/NDUFA3/UQCRC1	28
GO:0008137	NADH dehydrogenase (ubiquinone) activity	20/443	42/18367	9.14951570212575e-22	1.45477299663799e-19	NDUFB7/NDUFB10/NDUFC2/NDUFB9/NDUFS6/NDUFA13/NDUFS8/NDUFA4/NDUFB2/NDUFS5/NDUFB4/NDUFA1/NDUFV2/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/NDUFB8/NDUFA3	20
GO:0050136	NADH dehydrogenase (quinone) activity	20/443	43/18367	1.67300184630528e-21	2.12805834850032e-19	NDUFB7/NDUFB10/NDUFC2/NDUFB9/NDUFS6/NDUFA13/NDUFS8/NDUFA4/NDUFB2/NDUFS5/NDUFB4/NDUFA1/NDUFV2/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/NDUFB8/NDUFA3	20
GO:0003954	NADH dehydrogenase activity	20/443	45/18367	5.28111701757975e-21	4.79827203311531e-19	NDUFB7/NDUFB10/NDUFC2/NDUFB9/NDUFS6/NDUFA13/NDUFS8/NDUFA4/NDUFB2/NDUFS5/NDUFB4/NDUFA1/NDUFV2/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/NDUFB8/NDUFA3	20
GO:0003955	NAD(P)H dehydrogenase (quinone) activity	20/443	45/18367	5.28111701757975e-21	4.79827203311531e-19	NDUFB7/NDUFB10/NDUFC2/NDUFB9/NDUFS6/NDUFA13/NDUFS8/NDUFA4/NDUFB2/NDUFS5/NDUFB4/NDUFA1/NDUFV2/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/NDUFB8/NDUFA3	20
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	21/443	57/18367	6.41572264013412e-20	5.10049949890662e-18	NDUFB7/NDUFB10/NDUFC2/DCXR/NDUFB9/NDUFS6/NDUFA13/NDUFS8/NDUFA4/NDUFB2/NDUFS5/NDUFB4/NDUFA1/NDUFV2/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/NDUFB8/NDUFA3	21
GO:0016651	oxidoreductase activity, acting on NAD(P)H	22/443	88/18367	1.07790433519423e-16	7.61719063537258e-15	NDUFB7/NDUFB10/NDUFC2/DCXR/NDUFB9/NDUFS6/NDUFA13/NDUFS8/NDUFA4/NDUFB2/CYB5R1/NDUFS5/NDUFB4/NDUFA1/NDUFV2/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/NDUFB8/NDUFA3	22
GO:0015399	primary active transmembrane transporter activity	29/443	181/18367	5.34917849491228e-16	3.40207752276421e-14	COX6A1/NDUFB7/NDUFB10/NDUFC2/NDUFB9/UQCR10/NDUFS6/CYB5A/COX5B/NDUFA13/NDUFS8/NDUFA4/NDUFB2/NDUFS5/NDUFB4/NDUFA1/COX4I1/NDUFV2/COX5A/NDUFB3/NDUFA12/ATP2B1/NDUFA6/NDUFC1/NDUFS7/CYC1/NDUFB8/NDUFA3/UQCRC1	29
GO:0022804	active transmembrane transporter activity	35/443	406/18367	7.59019648291799e-11	4.38851360285076e-09	COX6A1/NDUFB7/NDUFB10/NDUFC2/NDUFB9/UQCR10/SLC25A3/NDUFS6/CYB5A/COX5B/SLC22A11/NDUFA13/NDUFS8/NDUFA4/NDUFB2/SLC6A4/SLC13A3/NDUFS5/NDUFB4/NDUFA1/COX4I1/NDUFV2/COX5A/NDUFB3/NDUFA12/ATP2B1/NDUFA6/NDUFC1/SLC19A1/NDUFS7/CYC1/NDUFB8/NDUFA3/UQCRC1/SLC1A5	35
GO:0019843	rRNA binding	12/443	68/18367	7.16635007637755e-08	3.7981655404801e-06	RPS14/RPL37/RPS18/RPL23/RPS5/RPL8/RPLP0/RPL23A/RPS3/MRPL20/NPM1/RPS4Y1	12
GO:0098631	cell adhesion mediator activity	11/443	59/18367	1.40117946557281e-07	6.85500107772544e-06	KRT18/ANXA2/BSG/DSP/BCAM/PDLIM1/RPSA/S100A11/DSC2/TRIM29/CD47	11
GO:0004298	threonine-type endopeptidase activity	6/443	14/18367	4.85092077540128e-07	2.20370400939658e-05	PSMB6/PSMB1/PSMB5/PSMB7/PSMB2/PSMA4	6
GO:0098632	cell-cell adhesion mediator activity	9/443	49/18367	2.22350884289991e-06	9.42767749389564e-05	KRT18/ANXA2/BSG/DSP/PDLIM1/S100A11/DSC2/TRIM29/CD47	9
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	9/443	55/18367	6.054791299382e-06	0.000240677954150434	MGST3/PRDX5/GSTP1/PRDX1/PRDX4/PRDX2/PRDX6/PARK7/GPX8	9
GO:0070003	threonine-type peptidase activity	6/443	24/18367	1.77107200957426e-05	0.000662589292993665	PSMB6/PSMB1/PSMB5/PSMB7/PSMB2/PSMA4	6
GO:0045296	cadherin binding	22/443	332/18367	2.01697191797298e-05	0.000712663411017121	KRT18/ITGA6/ANXA2/EGFR/PRDX1/BSG/CDH1/PSMB6/RPL34/RPL23A/PDLIM1/RPL7A/S100A11/IDH1/HSP90AB1/PRDX6/PARK7/CTNNAL1/RPS26/CD46/TRIM29/WASF2	22
GO:0004601	peroxidase activity	8/443	51/18367	2.75687321211139e-05	0.000876685681451423	MGST3/PRDX5/GSTP1/PRDX1/PRDX4/PRDX2/PRDX6/GPX8	8
GO:0016860	intramolecular oxidoreductase activity	8/443	51/18367	2.75687321211139e-05	0.000876685681451423	ECH1/P4HB/PDIA6/ECI2/ECI1/MIF/PDIA3/RPIA	8
GO:0016853	isomerase activity	14/443	158/18367	2.98633887079364e-05	0.000904434058011787	ISYNA1/DEGS1/PPIB/ECH1/P4HB/PDIA6/ECI2/HSPD1/ECI1/FKBP3/MIF/FKBP2/PDIA3/RPIA	14
GO:0016209	antioxidant activity	10/443	86/18367	4.14917419791778e-05	0.0011994885408526	MGST3/PRDX5/GSTP1/SOD1/PRDX1/PRDX4/PRDX2/PRDX6/PARK7/GPX8	10
GO:0043236	laminin binding	6/443	28/18367	4.56798472557247e-05	0.00126314708063656	TINAGL1/ITGA6/BCAM/RPSA/LGALS3/DAG1	6
GO:0098641	cadherin binding involved in cell-cell adhesion	5/443	18/18367	5.27376480458623e-05	0.00139754767321535	KRT18/ANXA2/PDLIM1/S100A11/TRIM29	5
GO:0050840	extracellular matrix binding	8/443	56/18367	5.53562250579178e-05	0.00140826236547343	TINAGL1/ITGA6/ANXA2/ADGRG1/BCAM/RPSA/LGALS3/DAG1	8
GO:0004129	cytochrome-c oxidase activity	5/443	19/18367	7.0159938939219e-05	0.0017162200448209	COX6A1/CYB5A/COX5B/COX4I1/COX5A	5
GO:0016675	oxidoreductase activity, acting on a heme group of donors	5/443	20/18367	9.17013653184801e-05	0.00216007660527975	COX6A1/CYB5A/COX5B/COX4I1/COX5A	5
GO:0000062	fatty-acyl-CoA binding	5/443	22/18367	0.000149678575010927	0.00339984191810535	ECI2/ACBD6/DBI/ACADVL/HADHA	5
GO:0051082	unfolded protein binding	11/443	122/18367	0.000180285733378903	0.00395385263548216	PPIB/HSPD1/HSP90B1/HSPE1/HSP90AB1/LMAN1/CALR/SIL1/NPM1/PFDN1/ERLEC1	11
GO:1901567	fatty acid derivative binding	5/443	23/18367	0.000187489918493082	0.00397478627205335	ECI2/ACBD6/DBI/ACADVL/HADHA	5
GO:1901681	sulfur compound binding	17/443	265/18367	0.000255426517351385	0.00524036338824132	GSTP1/ADGRG1/LRPAP1/NRP2/BMP7/ECI2/APP/ACBD6/FBN1/DBI/PDCD5/APLP2/ACADVL/HADHA/PCOLCE2/PRMT1/CCDC80	17
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	4/443	14/18367	0.000275785308069683	0.00548123299788495	ECH1/ECI2/ECI1/MIF	4
GO:0120227	acyl-CoA binding	5/443	25/18367	0.000284502914888777	0.00548314708694735	ECI2/ACBD6/DBI/ACADVL/HADHA	5
GO:0001618	virus receptor activity	8/443	76/18367	0.000483028706411119	0.00903547815521976	EGFR/BSG/RPSA/DAG1/CD46/CD55/ITGB5/SLC1A5	8
GO:0140272	exogenous protein binding	8/443	77/18367	0.000527876980503758	0.00959227884572543	EGFR/BSG/RPSA/DAG1/CD46/CD55/ITGB5/SLC1A5	8
GO:0015078	proton transmembrane transporter activity	10/443	130/18367	0.00122166807573128	0.0215828026712526	COX6A1/UQCR10/SLC25A3/CYB5A/COX5B/ATP6V1B1/COX4I1/COX5A/CYC1/UQCRC1	10
GO:0001848	complement binding	4/443	21/18367	0.00144246007545021	0.0246687346418626	CD59/C1QBP/CALR/PHB	4
GO:0004300	enoyl-CoA hydratase activity	3/443	10/18367	0.00147391810753267	0.0246687346418626	ECHS1/ECI1/HADHA	3
GO:0004602	glutathione peroxidase activity	4/443	22/18367	0.00172974485332561	0.0282081468388484	MGST3/GSTP1/PRDX6/GPX8	4
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	3/443	11/18367	0.00199052275594115	0.0316493118194643	DSP/DSC2/CD47	3
GO:0004867	serine-type endopeptidase inhibitor activity	8/443	98/18367	0.00254856885839753	0.0395338974131909	SERPINF1/SPINT2/SPINT1/ITIH5/PEBP1/ANXA2/APP/APLP2	8
GO:0005178	integrin binding	10/443	144/18367	0.00261615340097512	0.0396160372147661	EGFR/FBLN1/P4HB/ITGB4/FBN1/CALR/FERMT1/LAMA5/S1PR2/ITGB5	10
GO:0004859	phospholipase inhibitor activity	3/443	13/18367	0.00332859055820112	0.0481132635230889	ANXA2/ANXA3/ANXA5	3
GO:0031994	insulin-like growth factor I binding	3/443	13/18367	0.00332859055820112	0.0481132635230889	ITGA6/LRP2/ITGB4	3
GO:0016504	peptidase activator activity	5/443	43/18367	0.00361248891561208	0.0510565100073174	FBLN1/APP/BAD/PCOLCE2/CAV1	5
GO:0061134	peptidase regulator activity	13/443	230/18367	0.00399369362254729	0.0552171553030451	SERPINF1/SPINT2/SPINT1/ITIH5/PRDX5/PEBP1/ANXA2/FBLN1/APP/APLP2/BAD/PCOLCE2/CAV1	13
GO:0001846	opsonin binding	3/443	15/18367	0.00510923358325328	0.0691377140201933	C1QBP/CALR/PHB	3
GO:0048306	calcium-dependent protein binding	7/443	88/18367	0.00537146981079846	0.0711719749930796	ANXA2/ANXA3/CLN3/S100A11/S100A13/S100A10/PDCD6	7
GO:0022853	active ion transmembrane transporter activity	14/443	267/18367	0.00556244918474939	0.0721983200306247	COX6A1/UQCR10/SLC25A3/CYB5A/COX5B/SLC22A11/SLC6A4/SLC13A3/COX4I1/COX5A/ATP2B1/SLC19A1/CYC1/UQCRC1	14
GO:0004857	enzyme inhibitor activity	6/443	70/18367	0.00679672148633088	0.0864542973061288	ANXA2/RPL37/RPL23/RPS7/ANXA3/ANXA5	6
GO:0008201	heparin binding	10/443	166/18367	0.00711805033988188	0.0887662748267622	ADGRG1/LRPAP1/NRP2/BMP7/APP/FBN1/PDCD5/APLP2/PCOLCE2/CCDC80	10
GO:0055102	lipase inhibitor activity	3/443	18/18367	0.00868526667569688	0.104541132599491	ANXA2/ANXA3/ANXA5	3
GO:0033218	amide binding	18/443	400/18367	0.00871176104995756	0.104541132599491	LRPAP1/PPIB/FOLR1/ECI2/MME/CLTA/ACBD6/HSP90AB1/DBI/SRP14/CALR/FKBP3/ACADVL/KDELR1/FKBP2/SLC19A1/HADHA/PFDN1	18
GO:0005539	glycosaminoglycan binding	12/443	230/18367	0.0102326626659476	0.120442768416905	ADGRG1/LRPAP1/NRP2/BMP7/EXTL2/APP/FBN1/PDCD5/C1QBP/APLP2/PCOLCE2/CCDC80	12
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	8/443	124/18367	0.0104156482121538	0.120442768416905	LDHB/DCXR/HSD17B1/IDH1/ADH5/AKR1B1/HADHA/MDH2	8
GO:0003756	protein disulfide isomerase activity	3/443	20/18367	0.0117097195590256	0.125513656245289	P4HB/PDIA6/PDIA3	3
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	3/443	20/18367	0.0117097195590256	0.125513656245289	P4HB/PDIA6/PDIA3	3
GO:0031690	adrenergic receptor binding	3/443	20/18367	0.0117097195590256	0.125513656245289	GNAS/ADRB1/C1QBP	3
GO:0015035	protein-disulfide reductase activity	4/443	37/18367	0.0117594906762004	0.125513656245289	P4HB/PDIA6/PDIA3/TXN2	4
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	5/443	57/18367	0.0119518264698268	0.125513656245289	P4HB/PDIA6/MSRB2/PDIA3/TXN2	5
GO:0016835	carbon-oxygen lyase activity	6/443	79/18367	0.0120382594826456	0.125513656245289	ECHS1/RPS3/ECI1/HACD3/PARK7/HADHA	6
GO:0140678	molecular function inhibitor activity	8/443	128/18367	0.0124585256727529	0.127800360126949	ANXA2/RPL37/RPL23/RPS7/ANXA3/ANXA5/PHPT1/CAV1	8
GO:0051087	chaperone binding	7/443	107/18367	0.014996411188258	0.148222959935495	SOD1/LRP2/HSPD1/HSPE1/ERP29/TBCA/CALR	7
GO:0055106	ubiquitin-protein transferase regulator activity	3/443	22/18367	0.0152669059918437	0.148222959935495	RPL37/RPL23/RPS7	3
GO:0072349	modified amino acid transmembrane transporter activity	3/443	22/18367	0.0152669059918437	0.148222959935495	GJA1/SLC13A3/SLC19A1	3
GO:0044183	protein folding chaperone	4/443	40/18367	0.0153816279178344	0.148222959935495	WDR83OS/HSP90AB1/CALR/PFDN1	4
GO:0005507	copper ion binding	5/443	61/18367	0.0157119372649988	0.149146150754317	SOD1/F5/S100A13/CUTA/PARK7	5
GO:0016859	cis-trans isomerase activity	4/443	41/18367	0.0167282787961414	0.156458607563911	DEGS1/PPIB/FKBP3/FKBP2	4
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/443	23/18367	0.0172487773752056	0.158123786604563	ADI1/ETHE1/CDO1	3
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	8/443	136/18367	0.0174035614187412	0.158123786604563	LDHB/DCXR/HSD17B1/IDH1/ADH5/AKR1B1/HADHA/MDH2	8
GO:0015036	disulfide oxidoreductase activity	4/443	42/18367	0.0181464383776842	0.162551194481791	P4HB/PDIA6/PDIA3/TXN2	4
GO:0016836	hydro-lyase activity	5/443	64/18367	0.0189994508028258	0.167828482091628	ECHS1/ECI1/HACD3/PARK7/HADHA	5
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/443	24/18367	0.0193673338013301	0.168734579419808	ADI1/ETHE1/CDO1	3
GO:0097110	scaffold protein binding	5/443	67/18367	0.0227095763746991	0.192289795582382	KRT18/DSP/KRT8/PARK7/DYNLL2	5
GO:0005528	FK506 binding	2/443	10/18367	0.0229780258872029	0.192289795582382	FKBP3/FKBP2	2
GO:0016783	sulfurtransferase activity	2/443	10/18367	0.0229780258872029	0.192289795582382	TSTD1/MOCS2	2
GO:0051536	iron-sulfur cluster binding	5/443	68/18367	0.0240432162415104	0.196044686276931	NDUFS8/RPS3/CISD1/NDUFV2/NDUFS7	5
GO:0051540	metal cluster binding	5/443	68/18367	0.0240432162415104	0.196044686276931	NDUFS8/RPS3/CISD1/NDUFV2/NDUFS7	5
GO:0005518	collagen binding	5/443	69/18367	0.0254262918475509	0.204697741962562	CTSL/ADGRG1/PPIB/COL14A1/PCOLCE2	5
GO:0048027	mRNA 5'-UTR binding	3/443	27/18367	0.0265463675080695	0.211043621689153	RPS14/RPS7/MYH10	3
GO:0035673	oligopeptide transmembrane transporter activity	2/443	11/18367	0.0276419154719277	0.211810340242723	GJA1/SLC13A3	2
GO:0097493	structural molecule activity conferring elasticity	2/443	11/18367	0.0276419154719277	0.211810340242723	FBN2/FBN1	2
GO:1901612	cardiolipin binding	2/443	11/18367	0.0276419154719277	0.211810340242723	MME/STOML2	2
GO:0043021	ribonucleoprotein complex binding	8/443	149/18367	0.0282214308423574	0.212071184309264	RPLP1/RPSA/RPN2/SNRPG/C1QBP/SNRPD2/SNRPB2/NPM1	8
GO:0048029	monosaccharide binding	5/443	71/18367	0.0283428469595715	0.212071184309264	BSG/COLEC12/UGP2/LMAN1/RPIA	5
GO:0019903	protein phosphatase binding	8/443	150/18367	0.029210340540314	0.213560773497144	SOD1/EGFR/MET/HSP90B1/LGALS3/BAD/SNX3/KCNN4	8
GO:0001968	fibronectin binding	3/443	28/18367	0.0292135020349867	0.213560773497144	CTSL/FBLN1/CCDC80	3
GO:0004866	endopeptidase inhibitor activity	9/443	180/18367	0.0308465652191056	0.222936539538081	SERPINF1/SPINT2/SPINT1/ITIH5/PRDX5/PEBP1/ANXA2/APP/APLP2	9
GO:0005520	insulin-like growth factor binding	3/443	29/18367	0.0320168868876213	0.223276621139727	ITGA6/LRP2/ITGB4	3
GO:0003995	acyl-CoA dehydrogenase activity	2/443	12/18367	0.0326489398836394	0.223276621139727	TECR/ACADVL	2
GO:0005527	macrolide binding	2/443	12/18367	0.0326489398836394	0.223276621139727	FKBP3/FKBP2	2
GO:0017154	semaphorin receptor activity	2/443	12/18367	0.0326489398836394	0.223276621139727	NRP2/MET	2
GO:0045295	gamma-catenin binding	2/443	12/18367	0.0326489398836394	0.223276621139727	CDH1/DSC3	2
GO:0005310	dicarboxylic acid transmembrane transporter activity	3/443	30/18367	0.0349556832357855	0.236508665297443	SLC13A3/SLC19A1/SLC1A5	3
GO:0030414	peptidase inhibitor activity	9/443	187/18367	0.0379500724856402	0.244306485156926	SERPINF1/SPINT2/SPINT1/ITIH5/PRDX5/PEBP1/ANXA2/APP/APLP2	9
GO:0005542	folic acid binding	2/443	13/18367	0.0379799124882645	0.244306485156926	FOLR1/SLC19A1	2
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/443	13/18367	0.0379799124882645	0.244306485156926	DUSP9/DUSP14	2
GO:0031386	protein tag	2/443	13/18367	0.0379799124882645	0.244306485156926	RPS27A/NEDD8	2
GO:0016878	acid-thiol ligase activity	3/443	31/18367	0.0380288396706535	0.244306485156926	SLC27A2/ACSS1/SUCLG1	3
GO:0044548	S100 protein binding	2/443	14/18367	0.0436163689349358	0.277400106426192	ANXA2/S100A11	2
GO:0061135	endopeptidase regulator activity	9/443	194/18367	0.0460954951631033	0.290264702215185	SERPINF1/SPINT2/SPINT1/ITIH5/PRDX5/PEBP1/ANXA2/APP/APLP2	9
GO:0008376	acetylgalactosaminyltransferase activity	3/443	34/18367	0.0480410734189571	0.291738756781616	GALNT11/EXTL2/CHPF	3
GO:0016829	lyase activity	9/443	196/18367	0.0486210678266686	0.291738756781616	MGST3/ECHS1/GLDC/RPS3/ECI1/HACD3/PISD/PARK7/HADHA	9
GO:0019902	phosphatase binding	9/443	196/18367	0.0486210678266686	0.291738756781616	SOD1/EGFR/MET/HSP90B1/SH2D4A/LGALS3/BAD/SNX3/KCNN4	9
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/443	15/18367	0.0495405436044254	0.291738756781616	ALDH7A1/ADH5	2
GO:0050998	nitric-oxide synthase binding	2/443	15/18367	0.0495405436044254	0.291738756781616	SLC6A4/CAV1	2
GO:1901611	phosphatidylglycerol binding	2/443	15/18367	0.0495405436044254	0.291738756781616	MME/STOML2	2
GO:1904680	peptide transmembrane transporter activity	2/443	15/18367	0.0495405436044254	0.291738756781616	GJA1/SLC13A3	2
GO:0042887	amide transmembrane transporter activity	3/443	35/18367	0.0516374094239643	0.301297177923314	GJA1/SLC13A3/SLC19A1	3
GO:0019838	growth factor binding	7/443	141/18367	0.054935412239536	0.310944566187349	ITGA6/EGFR/NRP2/LRP2/RPS19/ITGB4/S100A13	7
GO:0042805	actinin binding	3/443	36/18367	0.0553601554303772	0.310944566187349	CSRP2/PDLIM1/DAG1	3
GO:0097718	disordered domain specific binding	3/443	36/18367	0.0553601554303772	0.310944566187349	GJA1/GJA5/HSP90AB1	3
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/443	16/18367	0.0557353467694305	0.310944566187349	ALDH7A1/ADH5	2
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/443	16/18367	0.0557353467694305	0.310944566187349	SLC13A3/SLC1A5	2
GO:0005201	extracellular matrix structural constituent	8/443	172/18367	0.0572955413793076	0.316869254932519	EFEMP1/TINAGL1/VWA1/FBN2/FBLN1/COL14A1/FBN1/LAMA5	8
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	3/443	37/18367	0.059207272908687	0.324619185947628	ALDH7A1/ADH5/AKR1B1	3
GO:0005324	long-chain fatty acid transporter activity	2/443	17/18367	0.0621843424461924	0.337649733370833	SLC2A1/SLC27A2	2
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3/443	38/18367	0.0631766010552345	0.337649733370833	PPIB/FKBP3/FKBP2	3
GO:0015175	neutral amino acid transmembrane transporter activity	3/443	38/18367	0.0631766010552345	0.337649733370833	SLC43A2/SLC38A9/SLC1A5	3
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	3/443	39/18367	0.0672658673456249	0.353562740758822	POLR2L/POLR2F/POLR2I	3
GO:0005504	fatty acid binding	3/443	39/18367	0.0672658673456249	0.353562740758822	GSTP1/ADH5/NDUFAB1	3
GO:0033549	MAP kinase phosphatase activity	2/443	18/18367	0.0688717269175043	0.359036215733875	DUSP9/DUSP14	2
GO:0051213	dioxygenase activity	5/443	92/18367	0.0716795420535331	0.370635680862171	P4HB/ADI1/ETHE1/CDO1/ASPH	5
GO:0016877	ligase activity, forming carbon-sulfur bonds	3/443	41/18367	0.0757946253673965	0.388753078497291	SLC27A2/ACSS1/SUCLG1	3
GO:0008509	anion transmembrane transporter activity	12/443	314/18367	0.0793084276617341	0.401777231655416	FXYD3/CLDN4/SLC2A1/CLIC3/SLC22A11/GJA1/SLC6A4/SLC13A3/MPC2/SLC38A9/SLC19A1/SLC1A5	12
GO:0008514	organic anion transmembrane transporter activity	8/443	185/18367	0.0799635943741645	0.401777231655416	SLC2A1/SLC22A11/GJA1/SLC13A3/MPC2/SLC38A9/SLC19A1/SLC1A5	8
GO:0008307	structural constituent of muscle	3/443	42/18367	0.0802291012896821	0.401777231655416	CSRP2/DAG1/ASPH	3
GO:0034062	5'-3' RNA polymerase activity	3/443	43/18367	0.0847735013968352	0.417953076654164	POLR2L/POLR2F/POLR2I	3
GO:0097747	RNA polymerase activity	3/443	43/18367	0.0847735013968352	0.417953076654164	POLR2L/POLR2F/POLR2I	3
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3/443	44/18367	0.0894251354196575	0.434673366521274	ALDH7A1/ADH5/AKR1B1	3
GO:0005243	gap junction channel activity	2/443	21/18367	0.0902152270138493	0.434673366521274	GJA1/GJA5	2
GO:0005385	zinc ion transmembrane transporter activity	2/443	21/18367	0.0902152270138493	0.434673366521274	SLC39A1/SLC39A10	2
GO:0005537	mannose binding	2/443	22/18367	0.0977100591160498	0.463758191028416	BSG/LMAN1	2
GO:0070034	telomerase RNA binding	2/443	22/18367	0.0977100591160498	0.463758191028416	NHP2/SNRPD3	2
GO:0033293	monocarboxylic acid binding	4/443	73/18367	0.0997039055623474	0.468460012734217	GSTP1/ADH5/NR2F2/NDUFAB1	4
GO:0046943	carboxylic acid transmembrane transporter activity	7/443	163/18367	0.100173839201027	0.468460012734217	SLC27A2/SLC13A3/SLC43A2/MPC2/SLC38A9/SLC19A1/SLC1A5	7
GO:0005342	organic acid transmembrane transporter activity	7/443	164/18367	0.102605618088016	0.476329730685971	SLC27A2/SLC13A3/SLC43A2/MPC2/SLC38A9/SLC19A1/SLC1A5	7
GO:0017134	fibroblast growth factor binding	2/443	23/18367	0.105373038329464	0.482138506313229	RPS19/S100A13	2
GO:0050750	low-density lipoprotein particle receptor binding	2/443	23/18367	0.105373038329464	0.482138506313229	LRPAP1/HSP90B1	2
GO:0008171	O-methyltransferase activity	2/443	24/18367	0.113191738741112	0.51056699176842	COMT/LCMT1	2
GO:0051537	2 iron, 2 sulfur cluster binding	2/443	24/18367	0.113191738741112	0.51056699176842	CISD1/NDUFV2	2
GO:0016763	pentosyltransferase activity	3/443	49/18367	0.114193953347058	0.511460241751614	QPRT/PARP1/PNP	3
GO:0008327	methyl-CpG binding	2/443	25/18367	0.121154233602234	0.536736832925268	DNMT1/PRMT1	2
GO:0030246	carbohydrate binding	10/443	271/18367	0.121525320662325	0.536736832925268	BSG/COLEC12/GALNT11/UGP2/AGL/LGALS3/LMAN1/CALR/RPIA/EMC7	10
GO:0031406	carboxylic acid binding	7/443	176/18367	0.134221839104414	0.588724756347635	GSTP1/FOLR1/GLDC/ADH5/NR2F2/NDUFAB1/SLC19A1	7
GO:0017069	snRNA binding	3/443	53/18367	0.135647932099317	0.590729242621824	LSM7/SNRPB2/SNRPD3	3
GO:0016405	CoA-ligase activity	2/443	27/18367	0.137465295452877	0.590729242621824	SLC27A2/ACSS1	2
GO:0051393	alpha-actinin binding	2/443	27/18367	0.137465295452877	0.590729242621824	PDLIM1/DAG1	2
GO:0005544	calcium-dependent phospholipid binding	3/443	54/18367	0.141214387105012	0.602767450998573	ANXA2/ANXA3/ANXA5	3
GO:0030165	PDZ domain binding	4/443	84/18367	0.144988284323963	0.610025912661017	GJA1/ADRB1/CADM1/ATP2B1	4
GO:0050681	androgen receptor binding	2/443	28/18367	0.145792356485023	0.610025912661017	PARK7/CALR	2
GO:0070325	lipoprotein particle receptor binding	2/443	28/18367	0.145792356485023	0.610025912661017	LRPAP1/HSP90B1	2
GO:0051287	NAD binding	3/443	56/18367	0.152569931411592	0.634212263907011	PARP1/IDH1/HADHA	3
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	2/443	29/18367	0.154220169047793	0.636909269574004	TECR/AKR1B1	2
GO:0022829	wide pore channel activity	2/443	30/18367	0.162739060891508	0.667755114367737	GJA1/GJA5	2
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	3/443	58/18367	0.164202444907074	0.66944073692884	GSTP1/SMS/FDFT1	3
GO:0003714	transcription corepressor activity	7/443	187/18367	0.166917707311771	0.672667228709218	C1QBP/PHB/EID2/TBL1X/CBX4/CCND1/HSBP1L1	7
GO:0042910	xenobiotic transmembrane transporter activity	2/443	31/18367	0.171339765803291	0.672667228709218	SLC2A1/SLC19A1	2
GO:0071813	lipoprotein particle binding	2/443	31/18367	0.171339765803291	0.672667228709218	COLEC12/HSPD1	2
GO:0071814	protein-lipid complex binding	2/443	31/18367	0.171339765803291	0.672667228709218	COLEC12/HSPD1	2
GO:0090482	vitamin transmembrane transporter activity	2/443	31/18367	0.171339765803291	0.672667228709218	SLC2A1/SLC19A1	2
GO:0140318	protein transporter activity	2/443	31/18367	0.171339765803291	0.672667228709218	LRP2/TIMM8B	2
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	3/443	60/18367	0.176088233363677	0.687068198891404	TECR/AKR1B1/ACADVL	3
GO:0001223	transcription coactivator binding	2/443	32/18367	0.180013409721062	0.693869870197546	RPL23/TFAM	2
GO:0030515	snoRNA binding	2/443	32/18367	0.180013409721062	0.693869870197546	NHP2/NUDT4	2
GO:0015179	L-amino acid transmembrane transporter activity	3/443	61/18367	0.182118773444735	0.694824721468144	SLC43A2/SLC38A9/SLC1A5	3
GO:0031625	ubiquitin protein ligase binding	10/443	297/18367	0.182446113970409	0.694824721468144	EGFR/RPL23/RPS27A/HSPD1/HSP90AB1/PSMA3/PRDX6/NEDD8/CALR/UQCRC1	10
GO:0072341	modified amino acid binding	4/443	93/18367	0.186921511931479	0.707631438026314	ANXA2/FOLR1/MME/SLC19A1	4
GO:0008200	ion channel inhibitor activity	2/443	33/18367	0.188751497278732	0.71021064809857	PHPT1/CAV1	2
GO:0042826	histone deacetylase binding	5/443	127/18367	0.19290062123124	0.71021064809857	PARP1/HSP90AB1/BEX4/PHB/CCND1	5
GO:0016248	channel inhibitor activity	2/443	34/18367	0.197545898769968	0.71021064809857	PHPT1/CAV1	2
GO:0030291	protein serine/threonine kinase inhibitor activity	2/443	34/18367	0.197545898769968	0.71021064809857	CDKN1C/PKIB	2
GO:0019207	kinase regulator activity	8/443	233/18367	0.202225814333495	0.71021064809857	CD24/GSTP1/CDKN1C/PKIB/RPLP1/HSP90AB1/NPM1/CCND1	8
GO:0016757	glycosyltransferase activity	9/443	270/18367	0.206353438479115	0.71021064809857	GALNT11/QPRT/EXTL2/PARP1/PNP/RPN2/AGL/OSTC/CHPF	9
GO:0043022	ribosome binding	3/443	66/18367	0.213032944481917	0.71021064809857	RPSA/RPN2/C1QBP	3
GO:0008330	protein tyrosine/threonine phosphatase activity	1/443	10/18367	0.216677168662754	0.71021064809857	DUSP9	1
GO:0015643	toxic substance binding	1/443	10/18367	0.216677168662754	0.71021064809857	ASS1	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/443	10/18367	0.216677168662754	0.71021064809857	CYB5R1	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/443	10/18367	0.216677168662754	0.71021064809857	DEGS1	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/443	10/18367	0.216677168662754	0.71021064809857	ADH5	1
GO:0019869	chloride channel inhibitor activity	1/443	10/18367	0.216677168662754	0.71021064809857	VAMP8	1
GO:0030957	Tat protein binding	1/443	10/18367	0.216677168662754	0.71021064809857	NPM1	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/443	10/18367	0.216677168662754	0.71021064809857	SLC27A2	1
GO:0032356	oxidized DNA binding	1/443	10/18367	0.216677168662754	0.71021064809857	RPS3	1
GO:0050786	RAGE receptor binding	1/443	10/18367	0.216677168662754	0.71021064809857	S100A13	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/443	10/18367	0.216677168662754	0.71021064809857	ADRB1	1
GO:0019887	protein kinase regulator activity	7/443	204/18367	0.223454905884411	0.71021064809857	CD24/CDKN1C/PKIB/RPLP1/HSP90AB1/NPM1/CCND1	7
GO:0042056	chemoattractant activity	2/443	37/18367	0.224190912197158	0.71021064809857	LGALS3/MIF	2
GO:0046915	transition metal ion transmembrane transporter activity	2/443	37/18367	0.224190912197158	0.71021064809857	SLC39A1/SLC39A10	2
GO:0016782	transferase activity, transferring sulphur-containing groups	3/443	68/18367	0.225701658626	0.71021064809857	TSTD1/TPST2/MOCS2	3
GO:0043177	organic acid binding	5/443	135/18367	0.227272818942269	0.71021064809857	FOLR1/GLDC/NR2F2/ASS1/SLC19A1	5
GO:0044390	ubiquitin-like protein conjugating enzyme binding	2/443	38/18367	0.233136151705043	0.71021064809857	RPS3/PARK7	2
GO:0044389	ubiquitin-like protein ligase binding	10/443	316/18367	0.234255987084057	0.71021064809857	EGFR/RPL23/RPS27A/HSPD1/HSP90AB1/PSMA3/PRDX6/NEDD8/CALR/UQCRC1	10
GO:0000774	adenyl-nucleotide exchange factor activity	1/443	11/18367	0.235580693981837	0.71021064809857	SIL1	1
GO:0002162	dystroglycan binding	1/443	11/18367	0.235580693981837	0.71021064809857	DAG1	1
GO:0005536	glucose binding	1/443	11/18367	0.235580693981837	0.71021064809857	UGP2	1
GO:0008603	cAMP-dependent protein kinase regulator activity	1/443	11/18367	0.235580693981837	0.71021064809857	PKIB	1
GO:0015378	sodium:chloride symporter activity	1/443	11/18367	0.235580693981837	0.71021064809857	SLC6A4	1
GO:0016273	arginine N-methyltransferase activity	1/443	11/18367	0.235580693981837	0.71021064809857	PRMT1	1
GO:0016274	protein-arginine N-methyltransferase activity	1/443	11/18367	0.235580693981837	0.71021064809857	PRMT1	1
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/443	11/18367	0.235580693981837	0.71021064809857	P4HB	1
GO:0019855	calcium channel inhibitor activity	1/443	11/18367	0.235580693981837	0.71021064809857	PHPT1	1
GO:0022889	serine transmembrane transporter activity	1/443	11/18367	0.235580693981837	0.71021064809857	SLC1A5	1
GO:0030283	testosterone dehydrogenase [NAD(P)] activity	1/443	11/18367	0.235580693981837	0.71021064809857	HSD17B1	1
GO:0047676	arachidonate-CoA ligase activity	1/443	11/18367	0.235580693981837	0.71021064809857	SLC27A2	1
GO:0061665	SUMO ligase activity	1/443	11/18367	0.235580693981837	0.71021064809857	CBX4	1
GO:0097371	MDM2/MDM4 family protein binding	1/443	11/18367	0.235580693981837	0.71021064809857	RPL37	1
GO:1990226	histone methyltransferase binding	1/443	11/18367	0.235580693981837	0.71021064809857	HSP90AB1	1
GO:0004860	protein kinase inhibitor activity	3/443	70/18367	0.238510929372753	0.71021064809857	CDKN1C/PKIB/NPM1	3
GO:0099106	ion channel regulator activity	5/443	139/18367	0.24509539603758	0.71021064809857	FXYD3/VAMP8/TSPAN13/PHPT1/CAV1	5
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/443	40/18367	0.251082608571888	0.71021064809857	PRDX5/BAD	2
GO:0030276	clathrin binding	3/443	72/18367	0.25143984498546	0.71021064809857	CLTA/AP1S1/NSG1	3
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/443	12/18367	0.254029035263491	0.71021064809857	RPS3	1
GO:0004032	alditol:NADP+ 1-oxidoreductase activity	1/443	12/18367	0.254029035263491	0.71021064809857	AKR1B1	1
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/443	12/18367	0.254029035263491	0.71021064809857	CDKN1C	1
GO:0008429	phosphatidylethanolamine binding	1/443	12/18367	0.254029035263491	0.71021064809857	PEBP1	1
GO:0015269	calcium-activated potassium channel activity	1/443	12/18367	0.254029035263491	0.71021064809857	KCNN4	1
GO:0017166	vinculin binding	1/443	12/18367	0.254029035263491	0.71021064809857	DAG1	1
GO:0031543	peptidyl-proline dioxygenase activity	1/443	12/18367	0.254029035263491	0.71021064809857	P4HB	1
GO:0033130	acetylcholine receptor binding	1/443	12/18367	0.254029035263491	0.71021064809857	LY6E	1
GO:0042975	peroxisome proliferator activated receptor binding	1/443	12/18367	0.254029035263491	0.71021064809857	HMGA1	1
GO:0043176	amine binding	1/443	12/18367	0.254029035263491	0.71021064809857	SLC6A4	1
GO:0043422	protein kinase B binding	1/443	12/18367	0.254029035263491	0.71021064809857	BAD	1
GO:0046790	virion binding	1/443	12/18367	0.254029035263491	0.71021064809857	ANXA2	1
GO:0051378	serotonin binding	1/443	12/18367	0.254029035263491	0.71021064809857	SLC6A4	1
GO:0106306	protein serine phosphatase activity	3/443	73/18367	0.257942813817879	0.71021064809857	DUSP9/DUSP14/CTDSPL	3
GO:0106307	protein threonine phosphatase activity	3/443	73/18367	0.257942813817879	0.71021064809857	DUSP9/DUSP14/CTDSPL	3
GO:0140104	molecular carrier activity	3/443	73/18367	0.257942813817879	0.71021064809857	PARK7/NDUFAB1/EMC7	3
GO:0048487	beta-tubulin binding	2/443	41/18367	0.260071735915707	0.71021064809857	PDCD5/TBCA	2
GO:0005254	chloride channel activity	3/443	74/18367	0.264468152229444	0.71021064809857	FXYD3/CLDN4/CLIC3	3
GO:0019210	kinase inhibitor activity	3/443	74/18367	0.264468152229444	0.71021064809857	CDKN1C/PKIB/NPM1	3
GO:0019905	syntaxin binding	3/443	74/18367	0.264468152229444	0.71021064809857	VAMP8/SLC6A4/TMED9	3
GO:0016922	nuclear receptor binding	5/443	144/18367	0.26786115908974	0.71021064809857	PARP1/PARK7/HMGA1/HMGN3/CALR	5
GO:0051539	4 iron, 4 sulfur cluster binding	2/443	42/18367	0.269063867647009	0.71021064809857	NDUFS8/NDUFS7	2
GO:0002161	aminoacyl-tRNA editing activity	1/443	13/18367	0.272033128828093	0.71021064809857	IARS2	1
GO:0008035	high-density lipoprotein particle binding	1/443	13/18367	0.272033128828093	0.71021064809857	HSPD1	1
GO:0016594	glycine binding	1/443	13/18367	0.272033128828093	0.71021064809857	GLDC	1
GO:0042301	phosphate ion binding	1/443	13/18367	0.272033128828093	0.71021064809857	PNP	1
GO:0052650	NADP-retinol dehydrogenase activity	1/443	13/18367	0.272033128828093	0.71021064809857	AKR1B1	1
GO:0060590	ATPase regulator activity	1/443	13/18367	0.272033128828093	0.71021064809857	SIL1	1
GO:0070700	BMP receptor binding	1/443	13/18367	0.272033128828093	0.71021064809857	BMP7	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/443	13/18367	0.272033128828093	0.71021064809857	HSD17B1	1
GO:0140299	small molecule sensor activity	1/443	13/18367	0.272033128828093	0.71021064809857	PARK7	1
GO:0016247	channel regulator activity	5/443	145/18367	0.272470751786244	0.71021064809857	FXYD3/VAMP8/TSPAN13/PHPT1/CAV1	5
GO:0008047	enzyme activator activity	4/443	110/18367	0.274408366530367	0.71234171882985	DDOST/GNAS/PDCD5/PARK7	4
GO:0005246	calcium channel regulator activity	2/443	43/18367	0.278053641610432	0.715959984065727	TSPAN13/PHPT1	2
GO:0030547	signaling receptor inhibitor activity	2/443	43/18367	0.278053641610432	0.715959984065727	LRPAP1/LY6E	2
GO:0038024	cargo receptor activity	3/443	77/18367	0.284154375709217	0.718439968466809	COLEC12/FOLR1/LRP2	3
GO:0015373	anion:sodium symporter activity	1/443	14/18367	0.289603648819875	0.718439968466809	SLC6A4	1
GO:0015562	efflux transmembrane transporter activity	1/443	14/18367	0.289603648819875	0.718439968466809	GJA1	1
GO:0015926	glucosidase activity	1/443	14/18367	0.289603648819875	0.718439968466809	AGL	1
GO:0032977	membrane insertase activity	1/443	14/18367	0.289603648819875	0.718439968466809	EMC7	1
GO:0043023	ribosomal large subunit binding	1/443	14/18367	0.289603648819875	0.718439968466809	NPM1	1
GO:0044594	17-beta-hydroxysteroid dehydrogenase (NAD+) activity	1/443	14/18367	0.289603648819875	0.718439968466809	HSD17B1	1
GO:0003712	transcription coregulator activity	14/443	489/18367	0.293662884906766	0.718439968466809	PAGE4/MAGED1/VGLL1/PDLIM1/PARK7/C1QBP/HMGA1/PHB/EID2/TBL1X/CBX4/NPM1/CCND1/HSBP1L1	14
GO:0140677	molecular function activator activity	5/443	150/18367	0.295754205120447	0.718439968466809	DDOST/GNAS/PDCD5/PARK7/DNAJC19	5
GO:0015103	inorganic anion transmembrane transporter activity	5/443	152/18367	0.305161827297093	0.718439968466809	FXYD3/CLDN4/CLIC3/SLC22A11/SLC6A4	5
GO:0004467	long-chain fatty acid-CoA ligase activity	1/443	15/18367	0.306751013478121	0.718439968466809	SLC27A2	1
GO:0005041	low-density lipoprotein particle receptor activity	1/443	15/18367	0.306751013478121	0.718439968466809	LRP2	1
GO:0005452	inorganic anion exchanger activity	1/443	15/18367	0.306751013478121	0.718439968466809	SLC22A11	1
GO:0010851	cyclase regulator activity	1/443	15/18367	0.306751013478121	0.718439968466809	GNAS	1
GO:0016846	carbon-sulfur lyase activity	1/443	15/18367	0.306751013478121	0.718439968466809	MGST3	1
GO:0030548	acetylcholine receptor regulator activity	1/443	15/18367	0.306751013478121	0.718439968466809	LY6E	1
GO:0032794	GTPase activating protein binding	1/443	15/18367	0.306751013478121	0.718439968466809	CDH1	1
GO:0045125	bioactive lipid receptor activity	1/443	15/18367	0.306751013478121	0.718439968466809	S1PR2	1
GO:0051371	muscle alpha-actinin binding	1/443	15/18367	0.306751013478121	0.718439968466809	PDLIM1	1
GO:0071933	Arp2/3 complex binding	1/443	15/18367	0.306751013478121	0.718439968466809	WASF2	1
GO:0099602	neurotransmitter receptor regulator activity	1/443	15/18367	0.306751013478121	0.718439968466809	LY6E	1
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	2/443	47/18367	0.31389067835721	0.718439968466809	DUSP9/DUSP14	2
GO:0003688	DNA replication origin binding	1/443	16/18367	0.3234853912587	0.718439968466809	HSPD1	1
GO:0005159	insulin-like growth factor receptor binding	1/443	16/18367	0.3234853912587	0.718439968466809	GNAS	1
GO:0015172	acidic amino acid transmembrane transporter activity	1/443	16/18367	0.3234853912587	0.718439968466809	SLC1A5	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/443	16/18367	0.3234853912587	0.718439968466809	SLC22A11	1
GO:0016208	AMP binding	1/443	16/18367	0.3234853912587	0.718439968466809	ACSS1	1
GO:0017070	U6 snRNA binding	1/443	16/18367	0.3234853912587	0.718439968466809	LSM7	1
GO:0032183	SUMO binding	1/443	16/18367	0.3234853912587	0.718439968466809	CBX4	1
GO:0070403	NAD+ binding	1/443	16/18367	0.3234853912587	0.718439968466809	HADHA	1
GO:1990404	protein ADP-ribosylase activity	1/443	16/18367	0.3234853912587	0.718439968466809	PARP1	1
GO:0008135	translation factor activity, RNA binding	3/443	84/18367	0.330441353803848	0.718439968466809	EIF3G/TUFM/EIF2S2	3
GO:0015171	amino acid transmembrane transporter activity	3/443	84/18367	0.330441353803848	0.718439968466809	SLC43A2/SLC38A9/SLC1A5	3
GO:0008013	beta-catenin binding	3/443	85/18367	0.337062937066047	0.718439968466809	CDH1/GJA1/TBL1X	3
GO:0050660	flavin adenine dinucleotide binding	3/443	85/18367	0.337062937066047	0.718439968466809	CYB5R1/ACADVL/ETFA	3
GO:0016758	hexosyltransferase activity	6/443	197/18367	0.339726607572552	0.718439968466809	GALNT11/EXTL2/RPN2/AGL/OSTC/CHPF	6
GO:0004659	prenyltransferase activity	1/443	17/18367	0.339816706809482	0.718439968466809	FDFT1	1
GO:0008381	mechanosensitive ion channel activity	1/443	17/18367	0.339816706809482	0.718439968466809	TMC5	1
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/443	17/18367	0.339816706809482	0.718439968466809	BAD	1
GO:0015095	magnesium ion transmembrane transporter activity	1/443	17/18367	0.339816706809482	0.718439968466809	TUSC3	1
GO:0015174	basic amino acid transmembrane transporter activity	1/443	17/18367	0.339816706809482	0.718439968466809	SLC38A9	1
GO:0015377	cation:chloride symporter activity	1/443	17/18367	0.339816706809482	0.718439968466809	SLC6A4	1
GO:0017081	chloride channel regulator activity	1/443	17/18367	0.339816706809482	0.718439968466809	VAMP8	1
GO:0030169	low-density lipoprotein particle binding	1/443	17/18367	0.339816706809482	0.718439968466809	COLEC12	1
GO:0034185	apolipoprotein binding	1/443	17/18367	0.339816706809482	0.718439968466809	HSPD1	1
GO:0043024	ribosomal small subunit binding	1/443	17/18367	0.339816706809482	0.718439968466809	NPM1	1
GO:0046965	retinoid X receptor binding	1/443	17/18367	0.339816706809482	0.718439968466809	HMGA1	1
GO:0050780	dopamine receptor binding	1/443	17/18367	0.339816706809482	0.718439968466809	GNAS	1
GO:0070064	proline-rich region binding	1/443	17/18367	0.339816706809482	0.718439968466809	CCND1	1
GO:0005048	signal sequence binding	2/443	50/18367	0.340517083347292	0.718439968466809	SRP14/KDELR1	2
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	2/443	50/18367	0.340517083347292	0.718439968466809	CDKN1C/CCND1	2
GO:0042562	hormone binding	3/443	86/18367	0.343680872231687	0.718439968466809	EGFR/LRP2/CALR	3
GO:0003743	translation initiation factor activity	2/443	51/18367	0.349323796761967	0.718439968466809	EIF3G/EIF2S2	2
GO:0051018	protein kinase A binding	2/443	51/18367	0.349323796761967	0.718439968466809	RPS3/WASF2	2
GO:0005253	anion channel activity	3/443	87/18367	0.350293299648493	0.718439968466809	FXYD3/CLDN4/CLIC3	3
GO:0004714	transmembrane receptor protein tyrosine kinase activity	4/443	124/18367	0.350643700472083	0.718439968466809	EFEMP1/EGFR/NRP2/MET	4
GO:0000295	adenine nucleotide transmembrane transporter activity	1/443	18/18367	0.355754646803128	0.718439968466809	SLC19A1	1
GO:0004303	estradiol 17-beta-dehydrogenase activity	1/443	18/18367	0.355754646803128	0.718439968466809	HSD17B1	1
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/443	18/18367	0.355754646803128	0.718439968466809	SLC19A1	1
GO:0008301	DNA binding, bending	1/443	18/18367	0.355754646803128	0.718439968466809	TFAM	1
GO:0016755	aminoacyltransferase activity	1/443	18/18367	0.355754646803128	0.718439968466809	TGM2	1
GO:0030228	lipoprotein particle receptor activity	1/443	18/18367	0.355754646803128	0.718439968466809	LRP2	1
GO:0047834	D-threo-aldose 1-dehydrogenase activity	1/443	18/18367	0.355754646803128	0.718439968466809	AKR1B1	1
GO:0048038	quinone binding	1/443	18/18367	0.355754646803128	0.718439968466809	NDUFS7	1
GO:0070122	isopeptidase activity	1/443	18/18367	0.355754646803128	0.718439968466809	PSMD7	1
GO:0140597	protein carrier activity	1/443	18/18367	0.355754646803128	0.718439968466809	EMC7	1
GO:1904047	S-adenosyl-L-methionine binding	1/443	18/18367	0.355754646803128	0.718439968466809	PRMT1	1
GO:0008276	protein methyltransferase activity	3/443	88/18367	0.356898407349017	0.718439968466809	TRMT112/LCMT1/PRMT1	3
GO:0016597	amino acid binding	2/443	52/18367	0.358090361641476	0.718439968466809	GLDC/ASS1	2
GO:1901682	sulfur compound transmembrane transporter activity	2/443	52/18367	0.358090361641476	0.718439968466809	GJA1/SLC13A3	2
GO:0050661	NADP binding	2/443	53/18367	0.366813594172541	0.720839771994021	HSD17B1/IDH1	2
GO:0016874	ligase activity	5/443	165/18367	0.367096097840317	0.720839771994021	SLC27A2/ACSS1/ASS1/SUCLG1/IARS2	5
GO:0042277	peptide binding	9/443	321/18367	0.370731494767937	0.720839771994021	LRPAP1/PPIB/MME/CLTA/HSP90AB1/SRP14/CALR/KDELR1/PFDN1	9
GO:0003746	translation elongation factor activity	1/443	19/18367	0.371308665630651	0.720839771994021	TUFM	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/443	19/18367	0.371308665630651	0.720839771994021	GALNT11	1
GO:0005326	neurotransmitter transmembrane transporter activity	1/443	19/18367	0.371308665630651	0.720839771994021	SLC6A4	1
GO:0010314	phosphatidylinositol-5-phosphate binding	1/443	19/18367	0.371308665630651	0.720839771994021	SNX3	1
GO:0035613	RNA stem-loop binding	1/443	19/18367	0.371308665630651	0.720839771994021	MYH10	1
GO:0035615	clathrin adaptor activity	1/443	19/18367	0.371308665630651	0.720839771994021	AP1S1	1
GO:0008374	O-acyltransferase activity	2/443	54/18367	0.375490486752061	0.720839771994021	PRDX6/LPCAT3	2
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	2/443	54/18367	0.375490486752061	0.720839771994021	P4HB/ASPH	2
GO:0005080	protein kinase C binding	2/443	55/18367	0.384118201372548	0.720839771994021	DSP/C1QBP	2
GO:0001972	retinoic acid binding	1/443	20/18367	0.386487990959058	0.720839771994021	NR2F2	1
GO:0004551	nucleotide diphosphatase activity	1/443	20/18367	0.386487990959058	0.720839771994021	NUDT4	1
GO:0016018	cyclosporin A binding	1/443	20/18367	0.386487990959058	0.720839771994021	PPIB	1
GO:0016408	C-acyltransferase activity	1/443	20/18367	0.386487990959058	0.720839771994021	HADHA	1
GO:0016500	protein-hormone receptor activity	1/443	20/18367	0.386487990959058	0.720839771994021	LGR5	1
GO:0016505	peptidase activator activity involved in apoptotic process	1/443	20/18367	0.386487990959058	0.720839771994021	BAD	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/443	20/18367	0.386487990959058	0.720839771994021	GLDC	1
GO:0030296	protein tyrosine kinase activator activity	1/443	20/18367	0.386487990959058	0.720839771994021	CD24	1
GO:0030506	ankyrin binding	1/443	20/18367	0.386487990959058	0.720839771994021	CDH1	1
GO:0031683	G-protein beta/gamma-subunit complex binding	1/443	20/18367	0.386487990959058	0.720839771994021	GNAS	1
GO:0042288	MHC class I protein binding	1/443	20/18367	0.386487990959058	0.720839771994021	BCAP31	1
GO:0140312	cargo adaptor activity	1/443	20/18367	0.386487990959058	0.720839771994021	AP1S1	1
GO:0016779	nucleotidyltransferase activity	4/443	132/18367	0.394483433750046	0.731311851413807	POLR2L/UGP2/POLR2F/POLR2I	4
GO:0044325	transmembrane transporter binding	4/443	133/18367	0.399939961404735	0.731311851413807	HSP90AB1/S100A10/PHPT1/CAV1	4
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/443	21/18367	0.401301629156319	0.731311851413807	LPCAT3	1
GO:0015216	purine nucleotide transmembrane transporter activity	1/443	21/18367	0.401301629156319	0.731311851413807	SLC19A1	1
GO:0015662	P-type ion transporter activity	1/443	21/18367	0.401301629156319	0.731311851413807	ATP2B1	1
GO:0051428	peptide hormone receptor binding	1/443	21/18367	0.401301629156319	0.731311851413807	GNAS	1
GO:0140358	P-type transmembrane transporter activity	1/443	21/18367	0.401301629156319	0.731311851413807	ATP2B1	1
GO:1990381	ubiquitin-specific protease binding	1/443	21/18367	0.401301629156319	0.731311851413807	PARK7	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	2/443	58/18367	0.409680308412356	0.731320841772855	SLC27A2/MPC2	2
GO:0002020	protease binding	4/443	135/18367	0.410826638148157	0.731320841772855	ANXA2/ADAMTSL4/PARK7/NDUFS7	4
GO:0008168	methyltransferase activity	6/443	214/18367	0.412840103964022	0.731320841772855	COMT/GCSH/DNMT1/TRMT112/LCMT1/PRMT1	6
GO:0005355	glucose transmembrane transporter activity	1/443	22/18367	0.415758370586808	0.731320841772855	SLC2A1	1
GO:0005540	hyaluronic acid binding	1/443	22/18367	0.415758370586808	0.731320841772855	C1QBP	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/443	22/18367	0.415758370586808	0.731320841772855	AKR1B1	1
GO:0015149	hexose transmembrane transporter activity	1/443	22/18367	0.415758370586808	0.731320841772855	SLC2A1	1
GO:0015296	anion:cation symporter activity	1/443	22/18367	0.415758370586808	0.731320841772855	SLC6A4	1
GO:0015645	fatty acid ligase activity	1/443	22/18367	0.415758370586808	0.731320841772855	SLC27A2	1
GO:0017075	syntaxin-1 binding	1/443	22/18367	0.415758370586808	0.731320841772855	SLC6A4	1
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/443	22/18367	0.415758370586808	0.731320841772855	PRDX5	1
GO:0070182	DNA polymerase binding	1/443	22/18367	0.415758370586808	0.731320841772855	HSP90AB1	1
GO:0004713	protein tyrosine kinase activity	4/443	136/18367	0.41625494453109	0.731320841772855	EFEMP1/EGFR/NRP2/MET	4
GO:0001664	G protein-coupled receptor binding	8/443	295/18367	0.418758758251655	0.73369303098637	WLS/GNAS/ITGB4/ADRB1/C1QBP/RNF43/PHB/S1PR2	8
GO:0004722	protein serine/threonine phosphatase activity	3/443	98/18367	0.422181916033738	0.734933552366359	DUSP9/DUSP14/CTDSPL	3
GO:0051015	actin filament binding	6/443	217/18367	0.425719895371059	0.734933552366359	EGFR/SLC6A4/MYH10/CTNNAL1/FERMT1/DSTN	6
GO:0001786	phosphatidylserine binding	2/443	60/18367	0.426430857544917	0.734933552366359	ANXA2/MME	2
GO:0003950	NAD+ ADP-ribosyltransferase activity	1/443	23/18367	0.429866794780323	0.734933552366359	PARP1	1
GO:0017025	TBP-class protein binding	1/443	23/18367	0.429866794780323	0.734933552366359	GTF2A2	1
GO:0019865	immunoglobulin binding	1/443	23/18367	0.429866794780323	0.734933552366359	LGALS3	1
GO:0042171	lysophosphatidic acid acyltransferase activity	1/443	23/18367	0.429866794780323	0.734933552366359	LPCAT3	1
GO:0070412	R-SMAD binding	1/443	23/18367	0.429866794780323	0.734933552366359	PARP1	1
GO:0071617	lysophospholipid acyltransferase activity	1/443	23/18367	0.429866794780323	0.734933552366359	LPCAT3	1
GO:0043621	protein self-association	2/443	61/18367	0.434712623107635	0.741225813127228	SLC2A1/MDH2	2
GO:0045182	translation regulator activity	4/443	140/18367	0.437847341621271	0.744464472833258	RPS14/EIF3G/TUFM/EIF2S2	4
GO:0015145	monosaccharide transmembrane transporter activity	1/443	24/18367	0.44363527547768	0.744464472833258	SLC2A1	1
GO:0015295	solute:proton symporter activity	1/443	24/18367	0.44363527547768	0.744464472833258	SLC25A3	1
GO:0019789	SUMO transferase activity	1/443	24/18367	0.44363527547768	0.744464472833258	CBX4	1
GO:0043495	protein-membrane adaptor activity	1/443	24/18367	0.44363527547768	0.744464472833258	PDCD6	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/443	24/18367	0.44363527547768	0.744464472833258	BMP7	1
GO:0003713	transcription coactivator activity	7/443	262/18367	0.445795808652397	0.746121406060327	PAGE4/MAGED1/VGLL1/PDLIM1/PARK7/HMGA1/NPM1	7
GO:0019199	transmembrane receptor protein kinase activity	4/443	143/18367	0.453891358393313	0.752551320110603	EFEMP1/EGFR/NRP2/MET	4
GO:0005112	Notch binding	1/443	25/18367	0.457071985555824	0.752551320110603	GALNT11	1
GO:0005227	calcium activated cation channel activity	1/443	25/18367	0.457071985555824	0.752551320110603	KCNN4	1
GO:0030247	polysaccharide binding	1/443	25/18367	0.457071985555824	0.752551320110603	AGL	1
GO:0034237	protein kinase A regulatory subunit binding	1/443	25/18367	0.457071985555824	0.752551320110603	WASF2	1
GO:0051019	mitogen-activated protein kinase binding	1/443	25/18367	0.457071985555824	0.752551320110603	PRMT1	1
GO:0015293	symporter activity	4/443	144/18367	0.459206506944843	0.752551320110603	SLC25A3/SLC6A4/SLC13A3/SLC1A5	4
GO:0016741	transferase activity, transferring one-carbon groups	6/443	225/18367	0.45983273709083	0.752551320110603	COMT/GCSH/DNMT1/TRMT112/LCMT1/PRMT1	6
GO:0015294	solute:cation symporter activity	3/443	104/18367	0.460286892331799	0.752551320110603	SLC25A3/SLC6A4/SLC13A3	3
GO:0004175	endopeptidase activity	11/443	430/18367	0.464387078608027	0.757057209031069	CTSL/PSMB6/PSMB1/MME/PSMB5/PSMB7/ADAMTS6/TMEM59/PSMB2/PDIA3/PSMA4	11
GO:0004364	glutathione transferase activity	1/443	26/18367	0.470184901835334	0.757057209031069	GSTP1	1
GO:0008198	ferrous iron binding	1/443	26/18367	0.470184901835334	0.757057209031069	CDO1	1
GO:0038187	pattern recognition receptor activity	1/443	26/18367	0.470184901835334	0.757057209031069	COLEC12	1
GO:0042974	retinoic acid receptor binding	1/443	26/18367	0.470184901835334	0.757057209031069	HMGA1	1
GO:0097602	cullin family protein binding	1/443	26/18367	0.470184901835334	0.757057209031069	DDB1	1
GO:0052689	carboxylic ester hydrolase activity	4/443	147/18367	0.475042997452972	0.760337700533922	PRDX6/PTRHD1/PON2/IARS2	4
GO:0002039	p53 binding	2/443	66/18367	0.47511720120802	0.760337700533922	HSPD1/TRIM29	2
GO:0001671	ATPase activator activity	1/443	27/18367	0.48298180977312	0.760337700533922	DNAJC19	1
GO:0004709	MAP kinase kinase kinase activity	1/443	27/18367	0.48298180977312	0.760337700533922	EGFR	1
GO:0015215	nucleotide transmembrane transporter activity	1/443	27/18367	0.48298180977312	0.760337700533922	SLC19A1	1
GO:0023026	MHC class II protein complex binding	1/443	27/18367	0.48298180977312	0.760337700533922	HSP90AB1	1
GO:0035255	ionotropic glutamate receptor binding	1/443	27/18367	0.48298180977312	0.760337700533922	GNAS	1
GO:0051119	sugar transmembrane transporter activity	1/443	27/18367	0.48298180977312	0.760337700533922	SLC2A1	1
GO:0051959	dynein light intermediate chain binding	1/443	27/18367	0.48298180977312	0.760337700533922	DYNLL2	1
GO:0090079	translation regulator activity, nucleic acid binding	3/443	108/18367	0.485083284071403	0.761760416467685	EIF3G/TUFM/EIF2S2	3
GO:0003684	damaged DNA binding	2/443	68/18367	0.490783536279582	0.762089663020713	RPS3/DDB1	2
GO:0003779	actin binding	11/443	440/18367	0.494934619029728	0.762089663020713	EGFR/P4HB/PDLIM1/SLC6A4/MYH10/DAG1/CTNNAL1/FERMT1/DSTN/MSRB2/WASF2	11
GO:0004629	phospholipase C activity	1/443	28/18367	0.49547030804305	0.762089663020713	PDIA3	1
GO:0046875	ephrin receptor binding	1/443	28/18367	0.49547030804305	0.762089663020713	EFNA1	1
GO:0051861	glycolipid binding	1/443	28/18367	0.49547030804305	0.762089663020713	CLN3	1
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	1/443	28/18367	0.49547030804305	0.762089663020713	SNX3	1
GO:1990756	ubiquitin ligase-substrate adaptor activity	1/443	28/18367	0.49547030804305	0.762089663020713	PDCD6	1
GO:0005506	iron ion binding	4/443	151/18367	0.495878310803866	0.762089663020713	ADI1/ETHE1/CDO1/CALR	4
GO:0000149	SNARE binding	3/443	110/18367	0.497275487662886	0.762089663020713	VAMP8/SLC6A4/TMED9	3
GO:0047485	protein N-terminus binding	3/443	110/18367	0.497275487662886	0.762089663020713	RPS21/PARP1/NPM1	3
GO:0004033	aldo-keto reductase (NADP) activity	1/443	29/18367	0.507657813007166	0.76873897398228	AKR1B1	1
GO:0015301	anion:anion antiporter activity	1/443	29/18367	0.507657813007166	0.76873897398228	SLC19A1	1
GO:0033612	receptor serine/threonine kinase binding	1/443	29/18367	0.507657813007166	0.76873897398228	BMP7	1
GO:0051059	NF-kappaB binding	1/443	29/18367	0.507657813007166	0.76873897398228	NPM1	1
GO:0070273	phosphatidylinositol-4-phosphate binding	1/443	29/18367	0.507657813007166	0.76873897398228	SNX3	1
GO:0031491	nucleosome binding	2/443	71/18367	0.513723387289489	0.776076186024026	HMGN3/ZNHIT1	2
GO:0005343	organic acid:sodium symporter activity	1/443	30/18367	0.51955156308012	0.777493633221074	SLC13A3	1
GO:0017147	Wnt-protein binding	1/443	30/18367	0.51955156308012	0.777493633221074	WLS	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/443	30/18367	0.51955156308012	0.777493633221074	HSD17B1	1
GO:0046966	thyroid hormone receptor binding	1/443	30/18367	0.51955156308012	0.777493633221074	HMGN3	1
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	4/443	156/18367	0.521415646603375	0.777864978899839	COMT/DNMT1/LCMT1/PRMT1	4
GO:0015291	secondary active transmembrane transporter activity	6/443	240/18367	0.522245827028665	0.777864978899839	SLC25A3/SLC22A11/SLC6A4/SLC13A3/SLC19A1/SLC1A5	6
GO:0015370	solute:sodium symporter activity	2/443	73/18367	0.528633382754764	0.781885654493092	SLC6A4/SLC13A3	2
GO:0035064	methylated histone binding	2/443	73/18367	0.528633382754764	0.781885654493092	MORC4/CBX4	2
GO:0140034	methylation-dependent protein binding	2/443	73/18367	0.528633382754764	0.781885654493092	MORC4/CBX4	2
GO:0000146	microfilament motor activity	1/443	31/18367	0.531158622989347	0.781983528289873	MYH10	1
GO:0016411	acylglycerol O-acyltransferase activity	1/443	31/18367	0.531158622989347	0.781983528289873	LPCAT3	1
GO:0003725	double-stranded RNA binding	2/443	74/18367	0.535971305824911	0.785924885479948	HSPD1/HSP90AB1	2
GO:0042393	histone binding	6/443	244/18367	0.538419516906428	0.785924885479948	CTSL/MORC4/RBBP7/TBL1X/CBX4/NPM1	6
GO:0140030	modification-dependent protein binding	4/443	160/18367	0.541396417233809	0.785924885479948	MORC4/HSPD1/AGL/CBX4	4
GO:0015605	organophosphate ester transmembrane transporter activity	1/443	32/18367	0.542485887933486	0.785924885479948	SLC19A1	1
GO:0048019	receptor antagonist activity	1/443	32/18367	0.542485887933486	0.785924885479948	LRPAP1	1
GO:0050699	WW domain binding	1/443	32/18367	0.542485887933486	0.785924885479948	TCEAL4	1
GO:0071889	14-3-3 protein binding	1/443	32/18367	0.542485887933486	0.785924885479948	BAD	1
GO:0001530	lipopolysaccharide binding	1/443	33/18367	0.553540087641447	0.791126956719012	HSPD1	1
GO:0004623	phospholipase A2 activity	1/443	33/18367	0.553540087641447	0.791126956719012	PRDX6	1
GO:0005154	epidermal growth factor receptor binding	1/443	33/18367	0.553540087641447	0.791126956719012	EFEMP1	1
GO:0031369	translation initiation factor binding	1/443	33/18367	0.553540087641447	0.791126956719012	EIF2S2	1
GO:0051427	hormone receptor binding	1/443	33/18367	0.553540087641447	0.791126956719012	GNAS	1
GO:0140323	solute:anion antiporter activity	1/443	33/18367	0.553540087641447	0.791126956719012	SLC19A1	1
GO:0015020	glucuronosyltransferase activity	1/443	34/18367	0.564327790334522	0.797869852629694	CHPF	1
GO:0016229	steroid dehydrogenase activity	1/443	34/18367	0.564327790334522	0.797869852629694	HSD17B1	1
GO:0016831	carboxy-lyase activity	1/443	34/18367	0.564327790334522	0.797869852629694	PISD	1
GO:0045505	dynein intermediate chain binding	1/443	34/18367	0.564327790334522	0.797869852629694	DYNLL2	1
GO:0001221	transcription coregulator binding	2/443	78/18367	0.564530556105916	0.797869852629694	RPL23/TFAM	2
GO:0046332	SMAD binding	2/443	79/18367	0.571470384797943	0.805887283218386	PARP1/EID2	2
GO:0000175	3'-5'-exoribonuclease activity	1/443	35/18367	0.574855406593825	0.8088673420214	REXO2	1
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	7/443	299/18367	0.584890323702619	0.814315463531887	PARP1/PARK7/HMGA1/HMGN3/CALR/GTF2A2/NPM1	7
GO:0000217	DNA secondary structure binding	1/443	36/18367	0.585129193135334	0.814315463531887	HMGA1	1
GO:0005484	SNAP receptor activity	1/443	36/18367	0.585129193135334	0.814315463531887	VAMP8	1
GO:0023023	MHC protein complex binding	1/443	36/18367	0.585129193135334	0.814315463531887	HSP90AB1	1
GO:0043394	proteoglycan binding	1/443	36/18367	0.585129193135334	0.814315463531887	CTSL	1
GO:0005109	frizzled binding	1/443	37/18367	0.595155256494728	0.819304638810924	RNF43	1
GO:0030551	cyclic nucleotide binding	1/443	37/18367	0.595155256494728	0.819304638810924	SLC19A1	1
GO:0043531	ADP binding	1/443	37/18367	0.595155256494728	0.819304638810924	MYH10	1
GO:0071855	neuropeptide receptor binding	1/443	37/18367	0.595155256494728	0.819304638810924	GNAS	1
GO:0071949	FAD binding	1/443	37/18367	0.595155256494728	0.819304638810924	CYB5R1	1
GO:0004520	endodeoxyribonuclease activity	1/443	38/18367	0.604939556624178	0.820509370854808	RPS3	1
GO:0005501	retinoid binding	1/443	38/18367	0.604939556624178	0.820509370854808	NR2F2	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/443	38/18367	0.604939556624178	0.820509370854808	GTF2A2	1
GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters	1/443	38/18367	0.604939556624178	0.820509370854808	REXO2	1
GO:0019840	isoprenoid binding	1/443	38/18367	0.604939556624178	0.820509370854808	NR2F2	1
GO:0001540	amyloid-beta binding	2/443	84/18367	0.604959283016522	0.820509370854808	LRPAP1/PFDN1	2
GO:0031072	heat shock protein binding	3/443	129/18367	0.605061155551737	0.820509370854808	HSP90AB1/RPS3/TFAM	3
GO:0004721	phosphoprotein phosphatase activity	4/443	174/18367	0.607754714230232	0.822408506915803	DUSP9/DUSP14/CTDSPL/PHPT1	4
GO:0017124	SH3 domain binding	3/443	130/18367	0.610293732111837	0.824090899412163	LRP2/GJA1/WASF2	3
GO:0019825	oxygen binding	1/443	39/18367	0.614487910403189	0.826910308234733	PARK7	1
GO:0004532	exoribonuclease activity	1/443	40/18367	0.62380599506553	0.826910308234733	REXO2	1
GO:0015144	carbohydrate transmembrane transporter activity	1/443	40/18367	0.62380599506553	0.826910308234733	SLC2A1	1
GO:0017080	sodium channel regulator activity	1/443	40/18367	0.62380599506553	0.826910308234733	FXYD3	1
GO:0031492	nucleosomal DNA binding	1/443	40/18367	0.62380599506553	0.826910308234733	HMGN3	1
GO:0042169	SH2 domain binding	1/443	40/18367	0.62380599506553	0.826910308234733	DAG1	1
GO:0042287	MHC protein binding	1/443	40/18367	0.62380599506553	0.826910308234733	BCAP31	1
GO:0043014	alpha-tubulin binding	1/443	40/18367	0.62380599506553	0.826910308234733	BEX4	1
GO:0003727	single-stranded RNA binding	2/443	87/18367	0.624083251497912	0.826910308234733	L1TD1/CBX4	2
GO:0004812	aminoacyl-tRNA ligase activity	1/443	41/18367	0.632899351544276	0.831661131368098	IARS2	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	1/443	41/18367	0.632899351544276	0.831661131368098	IARS2	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/443	41/18367	0.632899351544276	0.831661131368098	COL14A1	1
GO:0030331	estrogen receptor binding	1/443	41/18367	0.632899351544276	0.831661131368098	PARP1	1
GO:0008081	phosphoric diester hydrolase activity	2/443	89/18367	0.636430241527704	0.83285932841897	PDIA3/SMPDL3A	2
GO:0051117	ATPase binding	2/443	89/18367	0.636430241527704	0.83285932841897	EGFR/CAV1	2
GO:0001046	core promoter sequence-specific DNA binding	1/443	42/18367	0.641773387736892	0.838127052568097	NPM1	1
GO:0030544	Hsp70 protein binding	1/443	43/18367	0.650433381692284	0.845962435084443	RPS3	1
GO:0032266	phosphatidylinositol-3-phosphate binding	1/443	43/18367	0.650433381692284	0.845962435084443	SNX3	1
GO:0019955	cytokine binding	3/443	139/18367	0.65527592209856	0.848280429722625	NRP2/CSF2RA/PARK7	3
GO:0020037	heme binding	3/443	139/18367	0.65527592209856	0.848280429722625	HEBP2/CYB5A/CYC1	3
GO:0008375	acetylglucosaminyltransferase activity	1/443	44/18367	0.658884484721662	0.848280429722625	EXTL2	1
GO:0022839	ion gated channel activity	1/443	44/18367	0.658884484721662	0.848280429722625	KCNN4	1
GO:0051879	Hsp90 protein binding	1/443	44/18367	0.658884484721662	0.848280429722625	RPS3	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	2/443	94/18367	0.665903777504837	0.853713836500378	FUCA1/AGL	2
GO:0048156	tau protein binding	1/443	45/18367	0.667131724435044	0.853713836500378	HSP90AB1	1
GO:0140223	general transcription initiation factor activity	1/443	45/18367	0.667131724435044	0.853713836500378	GTF2A2	1
GO:0060090	molecular adaptor activity	8/443	369/18367	0.669351050248052	0.854833871401127	VAMP8/COL14A1/AP1S1/LAMTOR5/PDE4DIP/DDB1/CAV1/PDCD6	8
GO:0008022	protein C-terminus binding	4/443	189/18367	0.671961386278112	0.855137209812042	FBLN1/BCAM/PHB/TBL1X	4
GO:0008194	UDP-glycosyltransferase activity	3/443	143/18367	0.674035147491255	0.855137209812042	GALNT11/EXTL2/CHPF	3
GO:0004864	protein phosphatase inhibitor activity	1/443	46/18367	0.675180007705172	0.855137209812042	LGALS3	1
GO:0140296	general transcription initiation factor binding	1/443	46/18367	0.675180007705172	0.855137209812042	GTF2A2	1
GO:0046982	protein heterodimerization activity	7/443	328/18367	0.680713477912022	0.855137209812042	P4HB/ADRB1/TENM3/PHB/GTF2A2/TRMT112/CAV1	7
GO:0004896	cytokine receptor activity	2/443	97/18367	0.682646037698593	0.855137209812042	IL10RB/CSF2RA	2
GO:0005044	scavenger receptor activity	1/443	47/18367	0.683034123560562	0.855137209812042	COLEC12	1
GO:0019829	ATPase-coupled cation transmembrane transporter activity	1/443	47/18367	0.683034123560562	0.855137209812042	ATP2B1	1
GO:0035254	glutamate receptor binding	1/443	47/18367	0.683034123560562	0.855137209812042	GNAS	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/443	47/18367	0.683034123560562	0.855137209812042	ADRB1	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/443	48/18367	0.690698746009398	0.863034189512725	ASS1	1
GO:0019842	vitamin binding	3/443	148/18367	0.696414461721479	0.867911903453369	FOLR1/GLDC/SLC19A1	3
GO:0019212	phosphatase inhibitor activity	1/443	49/18367	0.698178436795895	0.867911903453369	LGALS3	1
GO:0005496	steroid binding	2/443	100/18367	0.698696375107114	0.867911903453369	HSD17B1/CAV1	2
GO:0046906	tetrapyrrole binding	3/443	149/18367	0.700748261663267	0.868377635564858	HEBP2/CYB5A/CYC1	3
GO:0030295	protein kinase activator activity	2/443	101/18367	0.703895098631335	0.868377635564858	CD24/RPLP1	2
GO:0015485	cholesterol binding	1/443	50/18367	0.705477648090764	0.868377635564858	CAV1	1
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/443	50/18367	0.705477648090764	0.868377635564858	SLC19A1	1
GO:0051020	GTPase binding	6/443	291/18367	0.706851061019759	0.868377635564858	ANXA2/SOD1/CLTA/STOML2/BNIP3/CAV1	6
GO:0004725	protein tyrosine phosphatase activity	2/443	102/18367	0.709019040342024	0.868377635564858	DUSP9/DUSP14	2
GO:0008227	G protein-coupled amine receptor activity	1/443	51/18367	0.71260072511734	0.868377635564858	ADRB1	1
GO:0008238	exopeptidase activity	2/443	103/18367	0.714068774036686	0.868377635564858	MME/GGH	2
GO:0005516	calmodulin binding	4/443	201/18367	0.717850246824305	0.868377635564858	EGFR/MYH10/KCNN4/ATP2B1	4
GO:0004620	phospholipase activity	2/443	104/18367	0.719044889364232	0.868377635564858	PRDX6/PDIA3	2
GO:0004879	nuclear receptor activity	1/443	52/18367	0.719551908714906	0.868377635564858	NR2F2	1
GO:0008146	sulfotransferase activity	1/443	52/18367	0.719551908714906	0.868377635564858	TPST2	1
GO:0016830	carbon-carbon lyase activity	1/443	52/18367	0.719551908714906	0.868377635564858	PISD	1
GO:0031593	polyubiquitin modification-dependent protein binding	1/443	52/18367	0.719551908714906	0.868377635564858	AGL	1
GO:0098531	ligand-activated transcription factor activity	1/443	52/18367	0.719551908714906	0.868377635564858	NR2F2	1
GO:0030674	protein-macromolecule adaptor activity	6/443	296/18367	0.722057812423908	0.869751455874253	VAMP8/COL14A1/AP1S1/DDB1/CAV1/PDCD6	6
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/443	53/18367	0.726335337840721	0.871602405408865	SLC19A1	1
GO:1901618	organic hydroxy compound transmembrane transporter activity	1/443	53/18367	0.726335337840721	0.871602405408865	SLC6A4	1
GO:0008408	3'-5' exonuclease activity	1/443	54/18367	0.732955052012205	0.873651567335583	REXO2	1
GO:0015459	potassium channel regulator activity	1/443	54/18367	0.732955052012205	0.873651567335583	CAV1	1
GO:0019209	kinase activator activity	2/443	107/18367	0.733537636725159	0.873651567335583	CD24/RPLP1	2
GO:1902936	phosphatidylinositol bisphosphate binding	2/443	107/18367	0.733537636725159	0.873651567335583	ANXA2/SNX3	2
GO:0140297	DNA-binding transcription factor binding	8/443	394/18367	0.737624319914513	0.876876761618001	PARP1/RPS3/PARK7/HMGA1/HMGN3/CALR/GTF2A2/NPM1	8
GO:0030170	pyridoxal phosphate binding	1/443	55/18367	0.739414993690717	0.877365552215105	GLDC	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/443	56/18367	0.745719010608313	0.878291279160902	PRDX5	1
GO:0030374	nuclear receptor coactivator activity	1/443	56/18367	0.745719010608313	0.878291279160902	HMGA1	1
GO:0042054	histone methyltransferase activity	1/443	56/18367	0.745719010608313	0.878291279160902	PRMT1	1
GO:0070279	vitamin B6 binding	1/443	56/18367	0.745719010608313	0.878291279160902	GLDC	1
GO:0004222	metalloendopeptidase activity	2/443	111/18367	0.751868755653981	0.88179675121932	MME/ADAMTS6	2
GO:0004536	deoxyribonuclease activity	1/443	57/18367	0.751870858038847	0.88179675121932	RPS3	1
GO:0008083	growth factor activity	3/443	162/18367	0.752854773446683	0.88179675121932	EFEMP1/BMP7/NENF	3
GO:0030546	signaling receptor activator activity	10/443	495/18367	0.758981882572803	0.887339112713792	EFEMP1/FAM3B/LRPAP1/BMP7/APP/NENF/FBN1/LGALS3/CMTM8/MIF	10
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/443	59/18367	0.763732616490772	0.891254943280974	REXO2	1
GO:0032934	sterol binding	1/443	60/18367	0.769449595455956	0.896281946355289	CAV1	1
GO:0098960	postsynaptic neurotransmitter receptor activity	1/443	62/18367	0.78047279030085	0.904925392319508	ADRB1	1
GO:1990841	promoter-specific chromatin binding	1/443	62/18367	0.78047279030085	0.904925392319508	DNMT1	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	3/443	170/18367	0.781138428275802	0.904925392319508	DEGS1/P4HB/ASPH	3
GO:0000287	magnesium ion binding	4/443	221/18367	0.783511038688736	0.906023673829156	COMT/IDH1/PPA1/PDCD6	4
GO:0004197	cysteine-type endopeptidase activity	2/443	119/18367	0.785290263383907	0.906126489175599	CTSL/PDIA3	2
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	4/443	222/18367	0.786449405699576	0.906126489175599	TGM2/PRDX6/HADHA/LPCAT3	4
GO:1901981	phosphatidylinositol phosphate binding	3/443	173/18367	0.791035592253614	0.909762453297104	PHLDA2/ANXA2/SNX3	3
GO:0005543	phospholipid binding	9/443	466/18367	0.795318478952528	0.912206623994522	PHLDA2/PEBP1/ANXA2/ANXA3/MME/ANXA5/BAD/STOML2/SNX3	9
GO:0030145	manganese ion binding	1/443	65/18367	0.796029365278238	0.912206623994522	EXTL2	1
GO:0003697	single-stranded DNA binding	2/443	123/18367	0.800470995890189	0.915646678752087	HSPD1/SSBP1	2
GO:0140101	catalytic activity, acting on a tRNA	2/443	124/18367	0.804114613949651	0.918163185766567	PTRHD1/IARS2	2
GO:0046873	metal ion transmembrane transporter activity	8/443	430/18367	0.817859027393764	0.932183407567086	ANXA2/TUSC3/SLC39A1/SLC6A4/SLC13A3/SLC39A10/KCNN4/ATP2B1	8
GO:0016298	lipase activity	2/443	129/18367	0.821459639232274	0.933348520065479	PRDX6/PDIA3	2
GO:0005125	cytokine activity	4/443	235/18367	0.821816306975894	0.933348520065479	FAM3B/BMP7/CMTM8/MIF	4
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/443	71/18367	0.82391987662333	0.934069592749444	TGM2	1
GO:0000049	tRNA binding	1/443	72/18367	0.828183294564731	0.937232340468272	IARS2	1
GO:0070063	RNA polymerase binding	1/443	73/18367	0.832343710006536	0.940267494785359	PPIB	1
GO:0048018	receptor ligand activity	9/443	487/18367	0.834424608037272	0.940946898425009	EFEMP1/FAM3B/LRPAP1/BMP7/NENF/FBN1/LGALS3/CMTM8/MIF	9
GO:0008234	cysteine-type peptidase activity	3/443	190/18367	0.840307496123471	0.942725128200974	CTSL/GGH/PDIA3	3
GO:0019003	GDP binding	1/443	75/18367	0.840365405689772	0.942725128200974	RAB17	1
GO:0015085	calcium ion transmembrane transporter activity	2/443	135/18367	0.840448345424454	0.942725128200974	ANXA2/ATP2B1	2
GO:0019001	guanyl nucleotide binding	7/443	398/18367	0.848615573228441	0.948540429830032	TGM2/GNAS/HSP90AB1/TUFM/SLC19A1/RHOC/RAB17	7
GO:0032561	guanyl ribonucleotide binding	7/443	398/18367	0.848615573228441	0.948540429830032	TGM2/GNAS/HSP90AB1/TUFM/SLC19A1/RHOC/RAB17	7
GO:0016746	acyltransferase activity	4/443	250/18367	0.856479253023857	0.954871468052412	TGM2/PRDX6/HADHA/LPCAT3	4
GO:0070851	growth factor receptor binding	2/443	141/18367	0.857591039460623	0.954871468052412	EFEMP1/APP	2
GO:0004527	exonuclease activity	1/443	80/18367	0.858783773154056	0.954871468052412	REXO2	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	2/443	144/18367	0.86551699027535	0.957365789708872	FUCA1/AGL	2
GO:0140375	immune receptor activity	2/443	144/18367	0.86551699027535	0.957365789708872	IL10RB/CSF2RA	2
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	1/443	82/18367	0.865542970255663	0.957365789708872	ANXA2	1
GO:0008528	G protein-coupled peptide receptor activity	2/443	147/18367	0.873036928571389	0.963978275297576	LGR5/S1PR2	2
GO:0042578	phosphoric ester hydrolase activity	6/443	366/18367	0.878969289493247	0.967558832432965	DUSP9/DUSP14/CTDSPL/PDIA3/PHPT1/SMPDL3A	6
GO:0051219	phosphoprotein binding	1/443	88/18367	0.88394440362686	0.967558832432965	CBX4	1
GO:0015081	sodium ion transmembrane transporter activity	2/443	152/18367	0.884715655358151	0.967558832432965	SLC6A4/SLC13A3	2
GO:0015297	antiporter activity	1/443	89/18367	0.886757064559805	0.967558832432965	SLC19A1	1
GO:0019888	protein phosphatase regulator activity	1/443	89/18367	0.886757064559805	0.967558832432965	LGALS3	1
GO:0043178	alcohol binding	1/443	89/18367	0.886757064559805	0.967558832432965	CAV1	1
GO:0001653	peptide receptor activity	2/443	153/18367	0.886928929730218	0.967558832432965	LGR5/S1PR2	2
GO:0005319	lipid transporter activity	2/443	154/18367	0.889102824445553	0.968269514293445	SLC2A1/SLC27A2	2
GO:0016407	acetyltransferase activity	1/443	91/18367	0.892179979613814	0.968504694357687	HADHA	1
GO:0015631	tubulin binding	6/443	375/18367	0.892364388197491	0.968504694357687	GJA1/RPS3/BEX4/PDCD5/DAG1/TBCA	6
GO:0005525	GTP binding	6/443	377/18367	0.895164056158971	0.969148050121748	TGM2/GNAS/HSP90AB1/TUFM/RHOC/RAB17	6
GO:0015267	channel activity	8/443	480/18367	0.896303812076776	0.969148050121748	FXYD3/CLDN4/ANXA2/CLIC3/GJA1/GJA5/KCNN4/TMC5	8
GO:0022803	passive transmembrane transporter activity	8/443	481/18367	0.897528618744826	0.969148050121748	FXYD3/CLDN4/ANXA2/CLIC3/GJA1/GJA5/KCNN4/TMC5	8
GO:0016410	N-acyltransferase activity	1/443	94/18367	0.899832365219322	0.969988786914388	TGM2	1
GO:0016791	phosphatase activity	4/443	275/18367	0.901511494784618	0.970154502001721	DUSP9/DUSP14/CTDSPL/PHPT1	4
GO:0008170	N-methyltransferase activity	1/443	97/18367	0.90694277142865	0.972776161544627	PRMT1	1
GO:0140098	catalytic activity, acting on RNA	6/443	386/18367	0.907006704081704	0.972776161544627	POLR2L/PTRHD1/REXO2/POLR2F/POLR2I/IARS2	6
GO:0005200	structural constituent of cytoskeleton	1/443	103/18367	0.919688163951424	0.983061634072447	DSP	1
GO:0031490	chromatin DNA binding	1/443	103/18367	0.919688163951424	0.983061634072447	HMGN3	1
GO:0019208	phosphatase regulator activity	1/443	107/18367	0.92720179106041	0.98943009918527	LGALS3	1
GO:0042626	ATPase-coupled transmembrane transporter activity	1/443	109/18367	0.930691305800061	0.991490235324688	ATP2B1	1
GO:0030594	neurotransmitter receptor activity	1/443	111/18367	0.934013913344679	0.991707594135586	ADRB1	1
GO:0032182	ubiquitin-like protein binding	1/443	111/18367	0.934013913344679	0.991707594135586	CBX4	1
GO:0003774	cytoskeletal motor activity	1/443	114/18367	0.938702195388751	0.995024327112076	MYH10	1
GO:0004540	ribonuclease activity	1/443	116/18367	0.941641561899875	0.996479256852447	REXO2	1
GO:0008237	metallopeptidase activity	2/443	190/18367	0.94577839113916	0.99666951960103	MME/ADAMTS6	2
GO:0005262	calcium channel activity	1/443	119/18367	0.945789011100121	0.99666951960103	ANXA2	1
GO:0005267	potassium channel activity	1/443	121/18367	0.948389252531518	0.99666951960103	KCNN4	1
GO:0005179	hormone activity	1/443	122/18367	0.949642325047606	0.99666951960103	FBN1	1
GO:0005216	ion channel activity	6/443	432/18367	0.95111464634905	0.99666951960103	FXYD3/CLDN4/ANXA2/CLIC3/KCNN4/TMC5	6
GO:0031267	small GTPase binding	3/443	259/18367	0.951223896851926	0.99666951960103	ANXA2/SOD1/CAV1	3
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1/443	125/18367	0.953222319846797	0.996669749568895	TGM2	1
GO:0008242	omega peptidase activity	1/443	126/18367	0.954358297936253	0.996669749568895	GGH	1
GO:0004519	endonuclease activity	1/443	129/18367	0.957603722025774	0.998419618374413	RPS3	1
GO:0035091	phosphatidylinositol binding	3/443	271/18367	0.960804433949685	0.999987316507082	PHLDA2/ANXA2/SNX3	3
GO:0003924	GTPase activity	4/443	337/18367	0.963984372416021	0.999987316507082	GNAS/TUFM/RHOC/RAB17	4
GO:0004518	nuclease activity	2/443	210/18367	0.963994609435047	0.999987316507082	RPS3/REXO2	2
GO:0005085	guanyl-nucleotide exchange factor activity	2/443	223/18367	0.972511501304987	0.999987316507082	ADRB1/LAMTOR5	2
GO:0140097	catalytic activity, acting on DNA	2/443	229/18367	0.975753223591501	0.999987316507082	DNMT1/RPS3	2
GO:0015079	potassium ion transmembrane transporter activity	1/443	155/18367	0.977639825316138	0.999987316507082	KCNN4	1
GO:0061659	ubiquitin-like protein ligase activity	3/443	316/18367	0.983170863104792	0.999987316507082	RNF43/CBX4/RNF181	3
GO:0022836	gated channel activity	3/443	340/18367	0.989430657493719	0.999987316507082	CLIC3/KCNN4/TMC5	3
GO:0016887	ATP hydrolysis activity	2/443	272/18367	0.990279738693297	0.999987316507082	HSPD1/ATP2B1	2
GO:0003730	mRNA 3'-UTR binding	1/443	201/18367	0.992807088345	0.999987316507082	RPS7	1
GO:0005244	voltage-gated ion channel activity	1/443	201/18367	0.992807088345	0.999987316507082	CLIC3	1
GO:0022832	voltage-gated channel activity	1/443	201/18367	0.992807088345	0.999987316507082	CLIC3	1
GO:0061630	ubiquitin protein ligase activity	2/443	304/18367	0.995146784219746	0.999987316507082	RNF43/RNF181	2
GO:0005261	cation channel activity	2/443	335/18367	0.997547411692185	0.999987316507082	ANXA2/KCNN4	2
GO:0005126	cytokine receptor binding	1/443	271/18367	0.998726752646736	0.999987316507082	MIF	1
GO:0008017	microtubule binding	1/443	271/18367	0.998726752646736	0.999987316507082	RPS3	1
GO:0019787	ubiquitin-like protein transferase activity	3/443	458/18367	0.999037588069971	0.999987316507082	RNF43/CBX4/RNF181	3
GO:0005096	GTPase activator activity	3/443	462/18367	0.999114994458633	0.999987316507082	ADRB1/HACD3/LAMTOR5	3
GO:0030695	GTPase regulator activity	3/443	488/18367	0.999488637923215	0.999987316507082	ADRB1/HACD3/LAMTOR5	3
GO:0060589	nucleoside-triphosphatase regulator activity	3/443	488/18367	0.999488637923215	0.999987316507082	ADRB1/HACD3/LAMTOR5	3
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	1/443	310/18367	0.999516198429327	0.999987316507082	NFE2L3	1
GO:0001217	DNA-binding transcription repressor activity	1/443	313/18367	0.999550941789883	0.999987316507082	NFE2L3	1
GO:0004842	ubiquitin-protein transferase activity	2/443	433/18367	0.999730111208222	0.999987316507082	RNF43/RNF181	2
GO:0004674	protein serine/threonine kinase activity	1/443	386/18367	0.999927040749269	0.999987316507082	EGFR	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	1/443	450/18367	0.999985260394354	0.999987316507082	TFDP2	1
GO:0001216	DNA-binding transcription activator activity	1/443	456/18367	0.999987316507082	0.999987316507082	TFDP2	1