ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0019646 aerobic electron transport chain 31/435 87/18722 8.46022628043227e-29 1.14422250058044e-25 COX6A1/COX7C/NDUFB7/COX6C/NDUFB10/NDUFC2/UQCRQ/NDUFB9/UQCR10/NDUFS6/COX5B/NDUFS8/NDUFA4/NDUFB2/COX7A2/PARK7/NDUFAB1/NDUFS5/NDUFB4/NDUFA1/COX4I1/NDUFV2/COX5A/NDUFB3/NDUFA6/NDUFC1/NDUFS7/CYC1/NDUFB8/NDUFA3/UQCRC1 31 GO:0042773 ATP synthesis coupled electron transport 32/435 95/18722 8.67492418938926e-29 1.14422250058044e-25 COX6A1/COX7C/NDUFB7/COX6C/NDUFB10/NDUFC2/UQCRQ/NDUFB9/UQCR10/NDUFS6/COX5B/NDUFS8/NDUFA4/NDUFB2/COX7A2/PARK7/NDUFAB1/NDUFS5/NDUFB4/NDUFA1/COX4I1/NDUFV2/COX5A/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/CYC1/NDUFB8/NDUFA3/UQCRC1 32 GO:0042775 mitochondrial ATP synthesis coupled electron transport 32/435 95/18722 8.67492418938926e-29 1.14422250058044e-25 COX6A1/COX7C/NDUFB7/COX6C/NDUFB10/NDUFC2/UQCRQ/NDUFB9/UQCR10/NDUFS6/COX5B/NDUFS8/NDUFA4/NDUFB2/COX7A2/PARK7/NDUFAB1/NDUFS5/NDUFB4/NDUFA1/COX4I1/NDUFV2/COX5A/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/CYC1/NDUFB8/NDUFA3/UQCRC1 32 GO:0022900 electron transport chain 40/435 175/18722 2.20968597037419e-28 2.18593184619267e-25 COX6A1/DEGS1/COX7C/NDUFB7/COX6C/NDUFB10/NDUFC2/UQCRQ/NDUFB9/GLDC/UQCR10/NDUFS6/CYB5A/COX5B/NDUFA13/NDUFS8/NDUFA4/NDUFB2/ADH5/COX7A2/PARK7/AKR1B1/NDUFAB1/NDUFS5/NDUFB4/NDUFA1/COX4I1/NDUFV2/ETFA/ASPH/COX5A/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/CYC1/NDUFB8/NDUFA3/UQCRC1 40 GO:0002181 cytoplasmic translation 36/435 148/18722 1.16706890444595e-26 9.23618330978527e-24 RPS21/RPL18/RPS14/RPS29/RPS12/RPS27/RPLP1/RPL37/RPS28/RPL37A/RPS16/RPS23/RPS18/RPLP2/RPL23/RPS5/RPS7/RPS27A/RPL34/RPL8/RPLP0/RPL10A/RPS19/RPS25/RPL27A/RPL36/RPL23A/RPSA/RPL31/RPS17/RPL7A/RPS3/RPS26/EIF3G/TMA7/EIF2S2 36 GO:0022904 respiratory electron transport chain 32/435 114/18722 5.95743336075215e-26 3.92892730141605e-23 COX6A1/COX7C/NDUFB7/COX6C/NDUFB10/NDUFC2/UQCRQ/NDUFB9/UQCR10/NDUFS6/COX5B/NDUFS8/NDUFA4/NDUFB2/COX7A2/PARK7/NDUFAB1/NDUFS5/NDUFB4/NDUFA1/COX4I1/NDUFV2/COX5A/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/CYC1/NDUFB8/NDUFA3/UQCRC1 32 GO:0006119 oxidative phosphorylation 33/435 141/18722 6.02830277753679e-24 3.40771344153044e-21 COX6A1/COX7C/NDUFB7/COX6C/NDUFB10/NDUFC2/UQCRQ/NDUFB9/UQCR10/NDUFS6/COX5B/NDUFS8/NDUFA4/NDUFB2/COX7A2/PARK7/NDUFAB1/NDUFS5/NDUFB4/NDUFA1/COX4I1/NDUFV2/STOML2/COX5A/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/CYC1/NDUFB8/NDUFA3/UQCRC1 33 GO:0009060 aerobic respiration 37/435 189/18722 8.7398720378081e-24 4.32295920670083e-21 COX6A1/COX7C/NDUFB7/COX6C/NDUFB10/NDUFC2/UQCRQ/NDUFB9/UQCR10/NDUFS6/COX5B/NDUFS8/NDUFA4/NDUFB2/IDH1/COX7A2/PARK7/NDUFAB1/NDUFS5/NDUFB4/NDUFA1/COX4I1/NDUFV2/STOML2/COX5A/NDUFB3/NDUFA12/NDUFA6/SUCLG1/NDUFC1/NDUFS7/MDH2/BNIP3/CYC1/NDUFB8/NDUFA3/UQCRC1 37 GO:0045333 cellular respiration 39/435 230/18722 1.28418324862637e-22 5.64612568312727e-20 COX6A1/COX7C/NDUFB7/COX6C/NDUFB10/NDUFC2/UQCRQ/NDUFB9/UQCR10/NDUFS6/COX5B/NDUFS8/NDUFA4/NDUFB2/IDH1/CISD1/IL10RB/COX7A2/PARK7/NDUFAB1/NDUFS5/NDUFB4/NDUFA1/COX4I1/NDUFV2/STOML2/COX5A/NDUFB3/NDUFA12/NDUFA6/SUCLG1/NDUFC1/NDUFS7/MDH2/BNIP3/CYC1/NDUFB8/NDUFA3/UQCRC1 39 GO:0006091 generation of precursor metabolites and energy 54/435 490/18722 1.0775870523729e-21 4.26401196623955e-19 PHLDA2/COX6A1/DEGS1/COX7C/NDUFB7/COX6C/NDUFB10/NDUFC2/UQCRQ/NDUFB9/GLDC/UGP2/UQCR10/NDUFS6/ACSS1/CYB5A/COX5B/NDUFA13/APP/NDUFS8/NDUFA4/NDUFB2/IDH1/ADH5/CISD1/IL10RB/COX7A2/PARK7/AGL/AKR1B1/NDUFAB1/NDUFS5/NDUFB4/NDUFA1/COX4I1/ACADVL/NDUFV2/STOML2/ETFA/ASPH/COX5A/NDUFB3/NDUFA12/NDUFA6/SUCLG1/NDUFC1/NDUFS7/MDH2/BNIP3/CYC1/NDUFB8/RPIA/NDUFA3/UQCRC1 54 GO:0015980 energy derivation by oxidation of organic compounds 43/435 318/18722 7.49286356180443e-21 2.69538737400547e-18 PHLDA2/COX6A1/COX7C/NDUFB7/COX6C/NDUFB10/NDUFC2/UQCRQ/NDUFB9/UGP2/UQCR10/NDUFS6/COX5B/NDUFS8/NDUFA4/NDUFB2/IDH1/CISD1/IL10RB/COX7A2/PARK7/AGL/NDUFAB1/NDUFS5/NDUFB4/NDUFA1/COX4I1/ACADVL/NDUFV2/STOML2/COX5A/NDUFB3/NDUFA12/NDUFA6/SUCLG1/NDUFC1/NDUFS7/MDH2/BNIP3/CYC1/NDUFB8/NDUFA3/UQCRC1 43 GO:0006120 mitochondrial electron transport, NADH to ubiquinone 20/435 51/18722 5.45104873650869e-20 1.79748332086374e-17 NDUFB7/NDUFB10/NDUFC2/NDUFB9/NDUFS6/NDUFS8/NDUFA4/NDUFB2/PARK7/NDUFAB1/NDUFS5/NDUFB4/NDUFA1/NDUFV2/NDUFB3/NDUFA6/NDUFC1/NDUFS7/NDUFB8/NDUFA3 20 GO:0010257 NADH dehydrogenase complex assembly 20/435 57/18722 7.48520726206493e-19 2.1156403668565e-16 NDUFB7/NDUFB10/NDUFC2/NDUFB9/NDUFA13/NDUFS8/NDUFB2/NDUFA11/NDUFAB1/NDUFB11/NDUFS5/NDUFB4/NDUFA1/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/NDUFB8/NDUFA3 20 GO:0032981 mitochondrial respiratory chain complex I assembly 20/435 57/18722 7.48520726206493e-19 2.1156403668565e-16 NDUFB7/NDUFB10/NDUFC2/NDUFB9/NDUFA13/NDUFS8/NDUFB2/NDUFA11/NDUFAB1/NDUFB11/NDUFS5/NDUFB4/NDUFA1/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/NDUFB8/NDUFA3 20 GO:0046034 ATP metabolic process 38/435 277/18722 9.23670804426218e-19 2.43664358207636e-16 COX6A1/COX7C/NDUFB7/COX6C/NDUFB10/NDUFC2/UQCRQ/NDUFB9/UQCR10/NDUFS6/PARP1/COX5B/APP/NDUFS8/NDUFA4/NDUFB2/COX7A2/PARK7/NDUFAB1/ATP6V1B1/NDUFS5/BAD/NDUFB4/NDUFA1/COX4I1/FIS1/NDUFV2/STOML2/COX5A/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/CYC1/NDUFB8/NDUFA3/UQCRC1 38 GO:0033108 mitochondrial respiratory chain complex assembly 23/435 93/18722 1.2394931001572e-17 3.06542137332627e-15 NDUFB7/NDUFB10/NDUFC2/NDUFB9/NDUFA13/NDUFS8/COA4/NDUFB2/NDUFA11/NDUFAB1/NDUFB11/NDUFS5/COX20/NDUFB4/NDUFA1/NDUFB3/NDUFA12/NDUFA6/NDUFC1/NDUFS7/TFAM/NDUFB8/NDUFA3 23 GO:0042274 ribosomal small subunit biogenesis 13/435 73/18722 1.17040914319167e-08 2.72429939977026e-06 RPS21/RPS14/RPS27/RPS28/RPS16/RPS5/RPS7/RPS19/RPS25/RPSA/RPS17/GTF2H5/NPM1 13 GO:0006979 response to oxidative stress 32/435 446/18722 1.83049379747036e-08 4.024035531439e-06 PAGE4/PRDX5/GSTP1/SOD1/EGFR/PRDX1/BMP7/P4HB/ARL6IP5/PRDX4/PRDX2/MET/PARP1/PDLIM1/HSPD1/APP/NDUFS8/PSMB5/IDH1/RPS3/ROMO1/PRDX6/PARK7/BAD/NDUFB4/PON2/NDUFA12/NDUFA6/MSRB2/BNIP3/TXN2/GPX8 32 GO:0042255 ribosome assembly 11/435 61/18722 1.38067176161655e-07 2.87543061090351e-05 RPS14/RPS27/RPS28/RPS5/RPLP0/RPS19/RPL23A/RPSA/C1QBP/MRPL20/NPM1 11 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen 7/435 21/18722 3.05637201909872e-07 6.04703203978681e-05 COX6A1/COX7C/COX6C/COX5B/COX7A2/COX4I1/COX5A 7 GO:0052547 regulation of peptidase activity 30/435 461/18722 4.27610887787446e-07 8.05741087130917e-05 SERPINF1/IFI6/SPINT2/SPINT1/ITIH5/CLDN4/PERP/PRDX5/PEBP1/ANXA2/FBLN1/ARL6IP5/NDUFA13/HSPD1/APP/HSPE1/BCAP31/RPS3/PSMA3/PDCD5/EFNA1/PARK7/APLP2/BAD/FIS1/LAMTOR5/ASPH/PCOLCE2/CAV1/PDCD6 30 GO:0022613 ribonucleoprotein complex biogenesis 30/435 463/18722 4.68522137771397e-07 8.42700954164282e-05 RPS21/RPS14/RPS27/RPS28/RPS16/RPS5/RPS7/RPLP0/RPL10A/RPS19/RPS25/RPL23A/RPSA/RPS17/RPL7A/HSP90AB1/NHP2/SNRPG/SNRPF/C1QBP/SNRPD2/GTF2H5/EIF3G/SNRPE/MRPL20/EIF2S2/NPM1/SNRPD3/TRMT112/MRPL36 30 GO:0006457 protein folding 19/435 212/18722 5.66997316231466e-07 9.75481904490396e-05 PPIB/P4HB/PRDX4/PDIA6/WDR83OS/HSPD1/HSP90B1/HSPE1/HSP90AB1/PDCD5/ERP29/LMAN1/TBCA/CALR/FKBP2/SIL1/DNAJC19/PDIA3/PFDN1 19 GO:0010952 positive regulation of peptidase activity 18/435 197/18722 8.48424142847108e-07 0.000139883930551917 CLDN4/PERP/FBLN1/ARL6IP5/NDUFA13/HSPD1/APP/HSPE1/BCAP31/RPS3/PDCD5/EFNA1/BAD/FIS1/ASPH/PCOLCE2/CAV1/PDCD6 18 GO:0046718 viral entry into host cell 15/435 144/18722 1.35246008438305e-06 0.00021406738215615 CTSL/EGFR/BSG/VAMP8/P4HB/RPSA/DAG1/LY6E/CD46/CD55/PHB/SNX3/CAV1/ITGB5/SLC1A5 15 GO:0042254 ribosome biogenesis 22/435 299/18722 2.12150081549179e-06 0.000322876104880809 RPS21/RPS14/RPS27/RPS28/RPS16/RPS5/RPS7/RPLP0/RPL10A/RPS19/RPS25/RPL23A/RPSA/RPS17/RPL7A/NHP2/C1QBP/GTF2H5/MRPL20/NPM1/TRMT112/MRPL36 22 GO:0044409 entry into host 15/435 151/18722 2.46501201643541e-06 0.000361261205519812 CTSL/EGFR/BSG/VAMP8/P4HB/RPSA/DAG1/LY6E/CD46/CD55/PHB/SNX3/CAV1/ITGB5/SLC1A5 15 GO:0000028 ribosomal small subunit assembly 6/435 19/18722 3.19036659612272e-06 0.000450867165030629 RPS14/RPS27/RPS28/RPS5/RPS19/RPSA 6 GO:0052126 movement in host environment 16/435 175/18722 3.41569334453611e-06 0.000466065467735496 CTSL/EGFR/BSG/VAMP8/P4HB/RPSA/DAG1/LY6E/CD46/CD55/PHB/SNX3/DDB1/CAV1/ITGB5/SLC1A5 16 GO:0097237 cellular response to toxic substance 13/435 124/18722 6.36749472975544e-06 0.000839872554854743 MGST3/PRDX5/GSTP1/SOD1/PRDX1/BMP7/PRDX4/PRDX2/ADH5/PRDX6/PARK7/FIS1/GPX8 13 GO:0052548 regulation of endopeptidase activity 26/435 432/18722 1.03484031527576e-05 0.00132092358953103 SERPINF1/IFI6/SPINT2/SPINT1/ITIH5/PERP/PRDX5/PEBP1/ANXA2/ARL6IP5/NDUFA13/HSPD1/APP/HSPE1/BCAP31/RPS3/PSMA3/PDCD5/EFNA1/PARK7/APLP2/BAD/FIS1/LAMTOR5/ASPH/PDCD6 26 GO:0044403 biological process involved in symbiotic interaction 20/435 290/18722 1.59779945179019e-05 0.00192301205578755 CTSL/EGFR/BSG/VAMP8/PPIB/P4HB/HSPD1/RPSA/HSP90AB1/ROMO1/DAG1/LY6E/CD46/CD55/PHB/SNX3/DDB1/CAV1/ITGB5/SLC1A5 20 GO:0022618 ribonucleoprotein complex assembly 17/435 220/18722 1.61945420811848e-05 0.00192301205578755 RPS14/RPS27/RPS28/RPS5/RPLP0/RPS19/RPL23A/RPSA/HSP90AB1/SNRPG/SNRPF/SNRPD2/EIF3G/SNRPE/MRPL20/EIF2S2/SNRPD3 17 GO:1990748 cellular detoxification 12/435 116/18722 1.65232271662312e-05 0.00192301205578755 MGST3/PRDX5/GSTP1/SOD1/PRDX1/BMP7/PRDX4/PRDX2/ADH5/PRDX6/PARK7/GPX8 12 GO:0019058 viral life cycle 21/435 317/18722 1.80498011840211e-05 0.00202988194324007 CTSL/EGFR/BSG/VAMP8/PPIB/P4HB/RPSA/HSP90AB1/HACD3/DAG1/LY6E/CD46/CD55/PHB/LAMTOR5/SPCS1/SNX3/DDB1/CAV1/ITGB5/SLC1A5 21 GO:1902600 proton transmembrane transport 14/435 157/18722 1.84674627133289e-05 0.00202988194324007 COX6A1/UQCR10/SLC25A3/CYB5A/COX5B/NDUFA4/PARK7/ATP6V1B1/COX4I1/STOML2/COX5A/NDUFS7/CYC1/UQCRC1 14 GO:0051701 biological process involved in interaction with host 16/435 203/18722 2.24445534841443e-05 0.00237661286260415 CTSL/EGFR/BSG/VAMP8/P4HB/RPSA/DAG1/LY6E/CD46/CD55/PHB/SNX3/DDB1/CAV1/ITGB5/SLC1A5 16 GO:0098869 cellular oxidant detoxification 11/435 101/18722 2.28231712860646e-05 0.00237661286260415 MGST3/PRDX5/GSTP1/SOD1/PRDX1/BMP7/PRDX4/PRDX2/PRDX6/PARK7/GPX8 11 GO:0071826 ribonucleoprotein complex subunit organization 17/435 227/18722 2.42638492289864e-05 0.00246184747177177 RPS14/RPS27/RPS28/RPS5/RPLP0/RPS19/RPL23A/RPSA/HSP90AB1/SNRPG/SNRPF/SNRPD2/EIF3G/SNRPE/MRPL20/EIF2S2/SNRPD3 17 GO:2001233 regulation of apoptotic signaling pathway 22/435 356/18722 3.32827809324911e-05 0.00329249910374668 IFI6/ITGA6/GSTP1/SOD1/MAGED1/RPS7/P4HB/PRDX2/PARP1/NDUFA13/BCAP31/RPS3/ERP29/PARK7/LGALS3/BAD/LMNA/MIF/FIS1/PDIA3/TNFRSF12A/CAV1 22 GO:0062197 cellular response to chemical stress 21/435 337/18722 4.4400899498145e-05 0.00426818362342815 PAGE4/PRDX5/SOD1/EGFR/PRDX1/SLC2A1/BMP7/P4HB/ARL6IP5/PRDX2/MET/PARP1/CLN3/RPS3/ROMO1/PARK7/AKR1B1/BAD/BNIP3/CAV1/GPX8 21 GO:0072593 reactive oxygen species metabolic process 17/435 239/18722 4.66348255594752e-05 0.00426818362342815 PAGE4/IFI6/PRDX5/GSTP1/SOD1/EGFR/PRDX1/BMP7/DCXR/PRDX4/PRDX2/NDUFA13/HSPD1/ROMO1/PRDX6/PARK7/BNIP3 17 GO:0097193 intrinsic apoptotic signaling pathway 19/435 288/18722 4.75717273209551e-05 0.00426818362342815 IFI6/CD24/PERP/SOD1/RPS7/P4HB/ARL6IP5/PARP1/NDUFA13/BCAP31/RPS3/ERP29/PARK7/BAD/MIF/SHISA5/FIS1/BNIP3/CAV1 19 GO:0048545 response to steroid hormone 21/435 339/18722 4.83659966999988e-05 0.00426818362342815 SERPINF1/CLDN4/GSTP1/EGFR/BMP7/ANXA3/PARP1/HSPD1/IDH1/PARK7/CDO1/AGL/CALR/BAD/ASS1/PHB/RBBP7/ATP2B1/SKP2/CCND1/CAV1 21 GO:0051205 protein insertion into membrane 8/435 57/18722 4.85388584923596e-05 0.00426818362342815 EGFR/WDR83OS/TIMM13/NDUFA13/ROMO1/TIMM8B/PDCD5/EMC7 8 GO:0051881 regulation of mitochondrial membrane potential 9/435 74/18722 5.2764609481207e-05 0.00453890347211165 IFI6/SOD1/HEBP2/ARL6IP5/PARP1/PARK7/BAD/STOML2/BNIP3 9 GO:0042743 hydrogen peroxide metabolic process 8/435 58/18722 5.51762017046137e-05 0.00454858812802409 PRDX5/SOD1/EGFR/PRDX1/PRDX4/PRDX2/PRDX6/PARK7 8 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 8/435 58/18722 5.51762017046137e-05 0.00454858812802409 SOD1/RPS7/BCAP31/RPS3/PARK7/BAD/FIS1/CAV1 8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 4/435 11/18722 8.33296389286175e-05 0.00646539963216744 UQCRQ/UQCR10/CYC1/UQCRC1 4 GO:0034975 protein folding in endoplasmic reticulum 4/435 11/18722 8.33296389286175e-05 0.00646539963216744 P4HB/HSP90B1/CALR/PDIA3 4 GO:0051561 positive regulation of mitochondrial calcium ion concentration 4/435 11/18722 8.33296389286175e-05 0.00646539963216744 TGM2/BCAP31/FIS1/BNIP3 4 GO:0030449 regulation of complement activation 5/435 21/18722 9.90038208034349e-05 0.00739176001942735 CD59/C1QBP/CD46/CD55/PHB 5 GO:0006839 mitochondrial transport 17/435 254/18722 9.90051253549785e-05 0.00739176001942735 HEBP2/SLC25A3/TIMM13/NDUFA13/HSPD1/BCAP31/ROMO1/TIMM8B/PDCD5/MPC2/LMAN1/BAD/FIS1/STOML2/DNAJC19/TMEM14C/BNIP3 17 GO:0006626 protein targeting to mitochondrion 10/435 100/18722 0.000110982969495107 0.00813258537578035 TIMM13/NDUFA13/HSPD1/BCAP31/ROMO1/TIMM8B/PDCD5/LMAN1/FIS1/DNAJC19 10 GO:0045039 protein insertion into mitochondrial inner membrane 4/435 12/18722 0.000122704012819154 0.00868488598981039 TIMM13/NDUFA13/ROMO1/TIMM8B 4 GO:2001242 regulation of intrinsic apoptotic signaling pathway 13/435 164/18722 0.000122909682949048 0.00868488598981039 SOD1/RPS7/P4HB/PARP1/NDUFA13/BCAP31/RPS3/ERP29/PARK7/BAD/MIF/FIS1/CAV1 13 GO:2000116 regulation of cysteine-type endopeptidase activity 16/435 235/18722 0.00012932127235641 0.00897761885463711 IFI6/PERP/PRDX5/ARL6IP5/NDUFA13/HSPD1/HSPE1/BCAP31/RPS3/PDCD5/PARK7/BAD/FIS1/LAMTOR5/ASPH/PDCD6 16 GO:0006575 cellular modified amino acid metabolic process 14/435 188/18722 0.000132804899551164 0.00906049978489582 GSTP1/SOD1/FOLR1/ALDH7A1/ARL6IP5/CLIC3/IDH1/SERINC2/GGH/ETHE1/PARK7/ASS1/SLC19A1/LPCAT3 14 GO:0045454 cell redox homeostasis 6/435 35/18722 0.000139298895587555 0.00934246999728737 PRDX5/PRDX1/PRDX4/PRDX2/PRDX6/TXN2 6 GO:0009636 response to toxic substance 17/435 262/18722 0.000144085413133577 0.00950243299615938 MGST3/PRDX5/GSTP1/SOD1/PRDX1/CDH1/BMP7/PRDX4/PRDX2/ADH5/SLC6A4/PRDX6/PARK7/ASS1/PON2/FIS1/GPX8 17 GO:2001235 positive regulation of apoptotic signaling pathway 11/435 126/18722 0.000173786294212778 0.0107865290485373 SOD1/MAGED1/RPS7/BCAP31/RPS3/PARK7/BAD/FIS1/PDIA3/TNFRSF12A/CAV1 11 GO:1900115 extracellular regulation of signal transduction 4/435 13/18722 0.000173993817226433 0.0107865290485373 LRPAP1/FBN2/FBN1/CD46 4 GO:1900116 extracellular negative regulation of signal transduction 4/435 13/18722 0.000173993817226433 0.0107865290485373 LRPAP1/FBN2/FBN1/CD46 4 GO:0007565 female pregnancy 14/435 193/18722 0.000174993182895897 0.0107865290485373 CLDN4/SOD1/BSG/SLC2A1/COMT/FBLN1/GJA1/ITGB4/MAGED2/NR2F2/C1QBP/AKR1B1/CALR/SLC19A1 14 GO:0045862 positive regulation of proteolysis 21/435 372/18722 0.00017858157321662 0.0107865290485373 CLDN4/PERP/FBLN1/ARL6IP5/NDUFA13/AURKAIP1/HSPD1/APP/HSPE1/BCAP31/RPS3/PDCD5/EFNA1/BAD/FIS1/ASPH/PSMC1/PCOLCE2/CAV1/PDCD6/LPCAT3 21 GO:2001056 positive regulation of cysteine-type endopeptidase activity 12/435 148/18722 0.000179911780946035 0.0107865290485373 PERP/ARL6IP5/NDUFA13/HSPD1/HSPE1/BCAP31/RPS3/PDCD5/BAD/FIS1/ASPH/PDCD6 12 GO:0044706 multi-multicellular organism process 15/435 220/18722 0.000205250602558656 0.0121220393182776 CLDN4/SOD1/BSG/SLC2A1/COMT/FBLN1/GJA1/ITGB4/SLC6A4/MAGED2/NR2F2/C1QBP/AKR1B1/CALR/SLC19A1 15 GO:0007566 embryo implantation 7/435 53/18722 0.000213398110276468 0.012417887093588 SOD1/BSG/FBLN1/GJA1/ITGB4/C1QBP/CALR 7 GO:0050878 regulation of body fluid levels 21/435 379/18722 0.000230128984347655 0.0130493044046257 CLDN4/ANXA2/EGFR/VAMP8/F5/FBLN1/PRDX2/CD59/MET/GNAS/GJA1/GJA5/ANXA5/CDO1/AKR1B1/ATP6V1B1/LMAN1/KCNN4/CCND1/CAV1/LSR 21 GO:0098754 detoxification 12/435 152/18722 0.000230844404428557 0.0130493044046257 MGST3/PRDX5/GSTP1/SOD1/PRDX1/BMP7/PRDX4/PRDX2/ADH5/PRDX6/PARK7/GPX8 12 GO:0051204 protein insertion into mitochondrial membrane 5/435 25/18722 0.000239432768479921 0.0133441614771134 TIMM13/NDUFA13/ROMO1/TIMM8B/PDCD5 5 GO:0010950 positive regulation of endopeptidase activity 13/435 179/18722 0.00029238089055999 0.0160687664436928 PERP/ARL6IP5/NDUFA13/HSPD1/HSPE1/BCAP31/RPS3/PDCD5/EFNA1/BAD/FIS1/ASPH/PDCD6 13 GO:0016032 viral process 22/435 415/18722 0.000304561319440381 0.0165088923428162 CTSL/EGFR/BSG/VAMP8/PPIB/P4HB/RPSA/HSP90AB1/HACD3/DAG1/EIF3G/LY6E/CD46/CD55/PHB/LAMTOR5/SPCS1/SNX3/DDB1/CAV1/ITGB5/SLC1A5 22 GO:0006635 fatty acid beta-oxidation 8/435 74/18722 0.000313995890443624 0.0167902937633165 ECHS1/ECH1/SLC27A2/ECI2/ECI1/ACADVL/ETFA/HADHA 8 GO:0032543 mitochondrial translation 8/435 76/18722 0.000377318670279186 0.0199073330439299 MRPS34/C1QBP/TUFM/MRPS15/MRPL52/CHCHD1/MRPL57/IARS2 8 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 14/435 209/18722 0.000396497540146976 0.0206439574521261 IFI6/PRDX5/ARL6IP5/NDUFA13/HSPD1/HSPE1/BCAP31/RPS3/PDCD5/PARK7/BAD/FIS1/LAMTOR5/PDCD6 14 GO:0090150 establishment of protein localization to membrane 16/435 260/18722 0.000405320355060781 0.0208292551295521 KRT18/CD24/EGFR/WDR83OS/TIMM13/NDUFA13/CLN3/ROMO1/TIMM8B/PDCD5/SRP14/FIS1/NSG1/SIL1/SSR2/EMC7 16 GO:0072655 establishment of protein localization to mitochondrion 10/435 120/18722 0.000493534872258148 0.0250374037118653 TIMM13/NDUFA13/HSPD1/BCAP31/ROMO1/TIMM8B/PDCD5/LMAN1/FIS1/DNAJC19 10 GO:0042177 negative regulation of protein catabolic process 10/435 121/18722 0.000527086294329596 0.026306572313345 ANXA2/EGFR/RPL23/RPS7/HSP90AB1/EFNA1/PARK7/ATRAID/PHB/SNX3 10 GO:0061450 trophoblast cell migration 4/435 17/18722 0.000537977503636085 0.026306572313345 GJA1/ITGB4/C1QBP/CALR 4 GO:0031960 response to corticosteroid 12/435 167/18722 0.000545035820145571 0.026306572313345 SERPINF1/GSTP1/EGFR/ANXA3/PARP1/HSPD1/CDO1/AGL/BAD/ASS1/ATP2B1/CCND1 12 GO:0001890 placenta development 11/435 144/18722 0.000551469242870084 0.026306572313345 SPINT2/SPINT1/PHLDA2/SOD1/BSG/BMP7/KRT8/MME/GJA1/HSP90AB1/NR2F2 11 GO:0051604 protein maturation 17/435 294/18722 0.00055179315188467 0.026306572313345 PERP/CTSL/GCSH/PRDX4/PARP1/MME/HSPD1/CLN3/PISD/NDUFAB1/CALR/BAD/STOML2/ASPH/SPCS1/TMEM59/LPCAT3 17 GO:0090151 establishment of protein localization to mitochondrial membrane 5/435 30/18722 0.000583716417323733 0.0274972126589287 TIMM13/NDUFA13/ROMO1/TIMM8B/PDCD5 5 GO:0097191 extrinsic apoptotic signaling pathway 14/435 219/18722 0.000631915934462387 0.0294175453255019 IFI6/KRT18/ITGA6/GSTP1/PRDX2/KRT8/NDUFA13/PARK7/LGALS3/BAD/LMNA/PDIA3/TNFRSF12A/CAV1 14 GO:0019395 fatty acid oxidation 9/435 103/18722 0.000663460803090375 0.0305269116026583 ECHS1/ECH1/SLC27A2/ECI2/ADH5/ECI1/ACADVL/ETFA/HADHA 9 GO:0070585 protein localization to mitochondrion 10/435 125/18722 0.000680775171224258 0.0308530901057414 TIMM13/NDUFA13/HSPD1/BCAP31/ROMO1/TIMM8B/PDCD5/LMAN1/FIS1/DNAJC19 10 GO:0006749 glutathione metabolic process 7/435 64/18722 0.000691005783439944 0.0308530901057414 GSTP1/SOD1/ARL6IP5/CLIC3/IDH1/ETHE1/PARK7 7 GO:0051384 response to glucocorticoid 11/435 148/18722 0.000693941121913314 0.0308530901057414 SERPINF1/GSTP1/EGFR/ANXA3/HSPD1/CDO1/AGL/BAD/ASS1/ATP2B1/CCND1 11 GO:0000302 response to reactive oxygen species 14/435 222/18722 0.000722299708220726 0.0317571105047712 PRDX5/GSTP1/SOD1/EGFR/PRDX1/BMP7/PRDX2/MET/HSPD1/RPS3/ROMO1/PARK7/BAD/BNIP3 14 GO:0042744 hydrogen peroxide catabolic process 5/435 32/18722 0.000793999248551322 0.0341505981143215 PRDX5/PRDX1/PRDX4/PRDX2/PRDX6 5 GO:0072337 modified amino acid transport 5/435 32/18722 0.000793999248551322 0.0341505981143215 FOLR1/LRP2/GJA1/SLC13A3/SLC19A1 5 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 10/435 128/18722 0.000818842084660095 0.0346612372828761 PEG10/CDKN1C/FBN2/FOLR1/FBN1/HSP90AB1/FERMT1/EID2/NREP/CAV1 10 GO:0006364 rRNA processing 14/435 225/18722 0.000823390524283639 0.0346612372828761 RPS21/RPS14/RPS27/RPS28/RPS16/RPS7/RPL10A/RPS19/RPS25/RPS17/RPL7A/NHP2/GTF2H5/TRMT112 14 GO:0051444 negative regulation of ubiquitin-protein transferase activity 4/435 19/18722 0.000844478380111203 0.0351747468431582 RPL37/RPL23/RPS7/PARK7 4 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 10/435 129/18722 0.00086967980657046 0.0358471145270762 ARL6IP5/NDUFA13/HSPD1/HSPE1/BCAP31/RPS3/PDCD5/BAD/FIS1/PDCD6 10 GO:0034440 lipid oxidation 9/435 108/18722 0.000934213275277203 0.0377212441864479 ECHS1/ECH1/SLC27A2/ECI2/ADH5/ECI1/ACADVL/ETFA/HADHA 9 GO:0140053 mitochondrial gene expression 9/435 108/18722 0.000934213275277203 0.0377212441864479 MRPS34/C1QBP/TUFM/MRPS15/MRPL52/CHCHD1/MRPL57/TFAM/IARS2 9 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 10/435 131/18722 0.000979142983675218 0.0391360483475034 PEG10/CDKN1C/FBN2/FOLR1/FBN1/HSP90AB1/FERMT1/EID2/NREP/CAV1 10 GO:0034614 cellular response to reactive oxygen species 11/435 155/18722 0.00101659649120419 0.0398471497308859 PRDX5/SOD1/EGFR/PRDX1/BMP7/PRDX2/MET/RPS3/ROMO1/PARK7/BNIP3 11 GO:0030490 maturation of SSU-rRNA 6/435 50/18722 0.00101707407703297 0.0398471497308859 RPS21/RPS14/RPS28/RPS16/RPS19/GTF2H5 6 GO:2000377 regulation of reactive oxygen species metabolic process 11/435 157/18722 0.00112871598661393 0.043787540774817 PAGE4/GSTP1/SOD1/EGFR/BMP7/DCXR/PRDX2/HSPD1/ROMO1/PARK7/BNIP3 11 GO:0034599 cellular response to oxidative stress 16/435 288/18722 0.00121149398003443 0.0465425405727792 PAGE4/PRDX5/SOD1/EGFR/PRDX1/BMP7/P4HB/ARL6IP5/PRDX2/MET/PARP1/RPS3/ROMO1/PARK7/BNIP3/GPX8 16 GO:0010038 response to metal ion 19/435 373/18722 0.00123257554887177 0.0468971292969768 SERPINF1/SOD1/EGFR/BSG/CDH1/HSD17B1/PARP1/CYB5A/APP/GGH/CUTA/PARK7/CALR/BAD/ASS1/BNIP3/CCND1/CAV1/PDCD6 19 GO:0060445 branching involved in salivary gland morphogenesis 4/435 21/18722 0.00125693292593475 0.0473684151230837 BMP7/TGM2/DAG1/LAMA5 4 GO:0016072 rRNA metabolic process 14/435 236/18722 0.00130226079744391 0.0481831083431367 RPS21/RPS14/RPS27/RPS28/RPS16/RPS7/RPL10A/RPS19/RPS25/RPS17/RPL7A/NHP2/GTF2H5/TRMT112 14 GO:1900180 regulation of protein localization to nucleus 10/435 136/18722 0.00130290437015811 0.0481831083431367 MAGED1/CDH1/PARP1/HSP90AB1/PARK7/LMNA/FERMT1/LAMTOR5/TRIM29/NPM1 10 GO:0097278 complement-dependent cytotoxicity 3/435 10/18722 0.00132362241648053 0.0484960546482729 CD59/HSP90AB1/CD55 3 GO:0042273 ribosomal large subunit biogenesis 7/435 72/18722 0.00139829638257602 0.0507620072096632 RPLP0/RPL10A/RPL23A/RPL7A/NHP2/MRPL20/NPM1 7 GO:0045861 negative regulation of proteolysis 18/435 351/18722 0.00152356601257546 0.0548068246523737 SERPINF1/IFI6/SPINT2/SPINT1/ITIH5/PRDX5/PEBP1/ANXA2/RPL23/RPS7/APP/CLN3/HSP90AB1/EFNA1/PARK7/APLP2/LAMTOR5/TMEM59 18 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5/435 37/18722 0.00156275487417065 0.0557100994332727 RPS21/RPS14/RPS16/RPS19/GTF2H5 5 GO:0032355 response to estradiol 10/435 141/18722 0.00170897518496786 0.0603787036331948 GSTP1/EGFR/BMP7/GJA1/SLC6A4/NR2F2/CALR/BAD/ASS1/CCND1 10 GO:1903363 negative regulation of cellular protein catabolic process 7/435 75/18722 0.001775465657654 0.0606297360638826 ANXA2/RPL23/RPS7/HSP90AB1/EFNA1/PARK7/ATRAID 7 GO:0001765 membrane raft assembly 3/435 11/18722 0.00178873220806251 0.0606297360638826 ANXA2/S100A10/CAV1 3 GO:0035581 sequestering of extracellular ligand from receptor 3/435 11/18722 0.00178873220806251 0.0606297360638826 FBN2/FBN1/CD46 3 GO:0018279 protein N-linked glycosylation via asparagine 4/435 23/18722 0.00179269121038015 0.0606297360638826 TUSC3/DDOST/RPN2/OSTC 4 GO:0019430 removal of superoxide radicals 4/435 23/18722 0.00179269121038015 0.0606297360638826 SOD1/PRDX1/BMP7/PRDX2 4 GO:1901654 response to ketone 12/435 194/18722 0.00199483217376628 0.0668944992507895 SERPINF1/CLDN4/EGFR/PARP1/PARK7/AKR1B1/CALR/BAD/ASS1/ATP2B1/CCND1/CAV1 12 GO:1900024 regulation of substrate adhesion-dependent cell spreading 6/435 57/18722 0.00202688645692355 0.0673982328575334 FBLN1/P4HB/S100A10/C1QBP/CALR/TACSTD2 6 GO:0006631 fatty acid metabolic process 19/435 390/18722 0.00204995221198555 0.0675971741902235 GSTP1/DEGS1/ECHS1/ECH1/SLC27A2/ACSS1/ECI2/ADH5/ECI1/HACD3/TECR/AKR1B1/NDUFAB1/ATP6V1B1/MIF/ACADVL/ETFA/HADHA/CAV1 19 GO:0018196 peptidyl-asparagine modification 4/435 24/18722 0.00211218019157625 0.0690735290749358 TUSC3/DDOST/RPN2/OSTC 4 GO:0009062 fatty acid catabolic process 8/435 100/18722 0.00229989814435822 0.0742040362946345 ECHS1/ECH1/SLC27A2/ECI2/ECI1/ACADVL/ETFA/HADHA 8 GO:0045916 negative regulation of complement activation 3/435 12/18722 0.00234407493981029 0.0742040362946345 CD59/CD46/CD55 3 GO:0098911 regulation of ventricular cardiac muscle cell action potential 3/435 12/18722 0.00234407493981029 0.0742040362946345 DSP/DSC2/CAV1 3 GO:1904667 negative regulation of ubiquitin protein ligase activity 3/435 12/18722 0.00234407493981029 0.0742040362946345 RPL37/RPL23/RPS7 3 GO:0007179 transforming growth factor beta receptor signaling pathway 12/435 198/18722 0.00236342722215111 0.0742228691908885 PEG10/CDKN1C/FBN2/FOLR1/PARP1/FBN1/HSP90AB1/FERMT1/EID2/NREP/CAV1/ITGB5 12 GO:0001836 release of cytochrome c from mitochondria 6/435 59/18722 0.00242084583871685 0.0745756756060271 IFI6/PDCD5/BAD/LMNA/FIS1/BNIP3 6 GO:0031579 membrane raft organization 4/435 25/18722 0.00246889398645175 0.0745756756060271 ANXA2/CLN3/S100A10/CAV1 4 GO:0032469 endoplasmic reticulum calcium ion homeostasis 4/435 25/18722 0.00246889398645175 0.0745756756060271 TGM2/APP/BCAP31/FIS1 4 GO:0071450 cellular response to oxygen radical 4/435 25/18722 0.00246889398645175 0.0745756756060271 SOD1/PRDX1/BMP7/PRDX2 4 GO:0071451 cellular response to superoxide 4/435 25/18722 0.00246889398645175 0.0745756756060271 SOD1/PRDX1/BMP7/PRDX2 4 GO:1905039 carboxylic acid transmembrane transport 10/435 149/18722 0.0025667490148931 0.0764656965893044 SLC2A1/FOLR1/LRP2/ARL6IP5/SLC13A3/SLC43A2/MPC2/SLC38A9/SLC19A1/SLC1A5 10 GO:0006790 sulfur compound metabolic process 17/435 339/18722 0.00257011312771733 0.0764656965893044 GSTP1/SOD1/COMT/SMS/ARL6IP5/ACSS1/CLIC3/TSTD1/ADI1/IDH1/ETHE1/PARK7/TECR/CDO1/MPC2/TPST2/CHPF 17 GO:1903825 organic acid transmembrane transport 10/435 150/18722 0.00269466552765216 0.0795730708426834 SLC2A1/FOLR1/LRP2/ARL6IP5/SLC13A3/SLC43A2/MPC2/SLC38A9/SLC19A1/SLC1A5 10 GO:2001236 regulation of extrinsic apoptotic signaling pathway 10/435 151/18722 0.00282763284960094 0.0828810606360809 IFI6/ITGA6/GSTP1/PRDX2/PARK7/LGALS3/LMNA/PDIA3/TNFRSF12A/CAV1 10 GO:0051560 mitochondrial calcium ion homeostasis 4/435 26/18722 0.00286490636186904 0.083356135837616 TGM2/BCAP31/FIS1/BNIP3 4 GO:0010917 negative regulation of mitochondrial membrane potential 3/435 13/18722 0.00299509927658544 0.0852633657370402 HEBP2/ARL6IP5/BNIP3 3 GO:0042769 DNA damage response, detection of DNA damage 3/435 13/18722 0.00299509927658544 0.0852633657370402 PARP1/RPS3/MRPS26 3 GO:0110096 cellular response to aldehyde 3/435 13/18722 0.00299509927658544 0.0852633657370402 ADH5/PARK7/AKR1B1 3 GO:0048732 gland development 20/435 436/18722 0.00316424124435717 0.0894350185994379 SERPINF1/KRT18/LMO4/SOD1/EGFR/CDH1/RPS16/BMP7/TGM2/PRDX2/MET/WLS/CDO1/DAG1/LY6E/ASS1/LAMA5/CCND1/CAV1/LSR 20 GO:0045785 positive regulation of cell adhesion 20/435 437/18722 0.00324676834259189 0.0908495344309489 CD24/ITGA6/ADGRG1/BMP7/P4HB/TGM2/HSPD1/PNP/RPS3/S100A10/C1QBP/DAG1/CALR/BAD/FERMT1/CD46/CD55/CAV1/CD47/CCDC80 20 GO:0098901 regulation of cardiac muscle cell action potential 4/435 27/18722 0.00330225245069044 0.0908495344309489 DSP/GJA5/DSC2/CAV1 4 GO:0030038 contractile actin filament bundle assembly 8/435 106/18722 0.00330612407330216 0.0908495344309489 MET/PDLIM1/S100A10/TACSTD2/RHOC/WASF2/ITGB5/CD47 8 GO:0043149 stress fiber assembly 8/435 106/18722 0.00330612407330216 0.0908495344309489 MET/PDLIM1/S100A10/TACSTD2/RHOC/WASF2/ITGB5/CD47 8 GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 9/435 130/18722 0.00336979847228632 0.0919373796508547 TMED4/BCAP31/ERGIC3/TMED9/LMAN1/YIF1A/KDELR1/TMED1/PDCD6 9 GO:0006835 dicarboxylic acid transport 7/435 84/18722 0.00339218029543209 0.0919373796508547 FOLR1/LRP2/ARL6IP5/GJA1/SLC13A3/SLC19A1/SLC1A5 7 GO:0030104 water homeostasis 6/435 64/18722 0.00365617076459743 0.0953441357308384 CLDN4/MET/CLN3/AKR1B1/ATP6V1B1/LSR 6 GO:0034446 substrate adhesion-dependent cell spreading 8/435 108/18722 0.00370814257346052 0.0953441357308384 FBLN1/P4HB/S100A10/EFNA1/C1QBP/CALR/LAMA5/TACSTD2 8 GO:0007569 cell aging 9/435 132/18722 0.00372968468826144 0.0953441357308384 SOD1/MME/ROMO1/HMGA1/YPEL3/CALR/LMNA/MIF/NPM1 9 GO:0006521 regulation of cellular amino acid metabolic process 3/435 14/18722 0.00374672602619119 0.0953441357308384 COMT/CLN3/PARK7 3 GO:0009071 serine family amino acid catabolic process 3/435 14/18722 0.00374672602619119 0.0953441357308384 GCSH/GLDC/CDO1 3 GO:0045837 negative regulation of membrane potential 3/435 14/18722 0.00374672602619119 0.0953441357308384 HEBP2/ARL6IP5/BNIP3 3 GO:0070141 response to UV-A 3/435 14/18722 0.00374672602619119 0.0953441357308384 EGFR/MME/CCND1 3 GO:0002920 regulation of humoral immune response 5/435 45/18722 0.0037641214128718 0.0953441357308384 CD59/C1QBP/CD46/CD55/PHB 5 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 5/435 45/18722 0.0037641214128718 0.0953441357308384 SOD1/P4HB/ARL6IP5/PARP1/PARK7 5 GO:0035272 exocrine system development 5/435 45/18722 0.0037641214128718 0.0953441357308384 BMP7/TGM2/WLS/DAG1/LAMA5 5 GO:0000303 response to superoxide 4/435 28/18722 0.0037829237578321 0.0953441357308384 SOD1/PRDX1/BMP7/PRDX2 4 GO:0003014 renal system process 8/435 110/18722 0.00414696626902939 0.103857883079426 CLDN4/COMT/GJA1/CLN3/GJA5/MAGED2/AKR1B1/ATP6V1B1 8 GO:0000305 response to oxygen radical 4/435 29/18722 0.00430886363652085 0.106304247197069 SOD1/PRDX1/BMP7/PRDX2 4 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 4/435 29/18722 0.00430886363652085 0.106304247197069 SOD1/P4HB/PARP1/PARK7 4 GO:0001101 response to acid chemical 9/435 135/18722 0.00432524230445492 0.106304247197069 GSTP1/KRT8/DNMT1/CDO1/AKR1B1/BAD/ASS1/LAMTOR5/SLC38A9 9 GO:0042311 vasodilation 5/435 47/18722 0.00455071846363198 0.110397297854113 SOD1/EGFR/GJA1/ADRB1/GJA5 5 GO:0086069 bundle of His cell to Purkinje myocyte communication 3/435 15/18722 0.00460337481575148 0.110397297854113 DSP/GJA5/DSC2 3 GO:0098760 response to interleukin-7 3/435 15/18722 0.00460337481575148 0.110397297854113 P4HB/HSPD1/PDIA3 3 GO:0098761 cellular response to interleukin-7 3/435 15/18722 0.00460337481575148 0.110397297854113 P4HB/HSPD1/PDIA3 3 GO:1900407 regulation of cellular response to oxidative stress 7/435 89/18722 0.00467666328040502 0.111479256629896 PAGE4/SOD1/BMP7/P4HB/MET/PARP1/PARK7 7 GO:0042176 regulation of protein catabolic process 18/435 391/18722 0.00480010238123903 0.113736557620137 ANXA2/EGFR/CDH1/RPL23/RPS7/LRP2/NDUFA13/GJA1/BCAP31/HSP90AB1/EFNA1/PARK7/ATRAID/PHB/SNX3/PSMC1/DDB1/CAV1 18 GO:0048608 reproductive structure development 19/435 424/18722 0.00508463542765096 0.119663299014218 SERPINF1/SPINT2/SPINT1/PHLDA2/SOD1/ADGRG1/BSG/BMP7/LRP2/PRDX4/KRT8/MME/GJA1/IDH1/HSP90AB1/NR2F2/EIF2S2/DNAJC19/CCND1 19 GO:1990778 protein localization to cell periphery 16/435 333/18722 0.00511071456492366 0.119663299014218 KRT18/ANXA2/EGFR/BSG/CDH1/VAMP8/TMEM150A/ARL6IP5/CLN3/S100A10/LGALS3/DAG1/NSG1/TMEM59/LAMA5/CAV1 16 GO:0050821 protein stabilization 11/435 191/18722 0.00518352978934255 0.120654278684873 PPIB/RPL23/RPS7/HSPD1/HSP90AB1/EFNA1/PARK7/CALR/PHB/TBL1X/NPM1 11 GO:0043457 regulation of cellular respiration 5/435 49/18722 0.00544766906298182 0.123800518229776 CISD1/IL10RB/COX7A2/PARK7/BNIP3 5 GO:0061458 reproductive system development 19/435 427/18722 0.00547409726621479 0.123800518229776 SERPINF1/SPINT2/SPINT1/PHLDA2/SOD1/ADGRG1/BSG/BMP7/LRP2/PRDX4/KRT8/MME/GJA1/IDH1/HSP90AB1/NR2F2/EIF2S2/DNAJC19/CCND1 19 GO:0010498 proteasomal protein catabolic process 21/435 490/18722 0.00549686902264217 0.123800518229776 PSMB6/PSMB1/HSP90B1/PSMB5/BCAP31/HSP90AB1/PSMA7/PSMA3/PSMD7/PARK7/PSMB7/CALR/PSMB2/TBL1X/PSMD8/PSMC1/SKP2/DDB1/PSMA4/CAV1/ERLEC1 21 GO:0071711 basement membrane organization 4/435 31/18722 0.00550405770472562 0.123800518229776 SPINT2/DAG1/FERMT1/CAV1 4 GO:0002921 negative regulation of humoral immune response 3/435 16/18722 0.00556898970050548 0.123800518229776 CD59/CD46/CD55 3 GO:0010649 regulation of cell communication by electrical coupling 3/435 16/18722 0.00556898970050548 0.123800518229776 GJA1/GJA5/CAV1 3 GO:0097202 activation of cysteine-type endopeptidase activity 3/435 16/18722 0.00556898970050548 0.123800518229776 PERP/BAD/ASPH 3 GO:1901163 regulation of trophoblast cell migration 3/435 16/18722 0.00556898970050548 0.123800518229776 GJA1/C1QBP/CALR 3 GO:0001666 response to hypoxia 15/435 307/18722 0.00567678760413413 0.125438313666085 CD24/SLC2A1/BMP7/P4HB/PDLIM1/HSPD1/HSP90B1/SLC6A4/HILPDA/BAD/LMNA/FIS1/BNIP3/CAV1/TXN2 15 GO:0007006 mitochondrial membrane organization 8/435 116/18722 0.00570606430626618 0.125438313666085 HEBP2/TIMM13/NDUFA13/ROMO1/TIMM8B/PDCD5/BAD/BNIP3 8 GO:0071560 cellular response to transforming growth factor beta stimulus 13/435 250/18722 0.00586663530491583 0.127830138546393 PEG10/CDKN1C/FBN2/FOLR1/PARP1/FBN1/HSP90AB1/PDCD5/FERMT1/EID2/NREP/CAV1/ITGB5 13 GO:0000387 spliceosomal snRNP assembly 5/435 50/18722 0.00593995739475391 0.127830138546393 SNRPG/SNRPF/SNRPD2/SNRPE/SNRPD3 5 GO:2000677 regulation of transcription regulatory region DNA binding 5/435 50/18722 0.00593995739475391 0.127830138546393 PARP1/PARK7/MSX2/ZNF593/LAMTOR5 5 GO:0007589 body fluid secretion 7/435 93/18722 0.0059440852900016 0.127830138546393 ANXA2/EGFR/VAMP8/CDO1/KCNN4/CCND1/CAV1 7 GO:0007435 salivary gland morphogenesis 4/435 32/18722 0.0061769231984648 0.132119378899055 BMP7/TGM2/DAG1/LAMA5 4 GO:0031032 actomyosin structure organization 11/435 196/18722 0.0062669727905417 0.133258247597432 MET/KRT8/CSRP2/PDLIM1/MYH10/S100A10/TACSTD2/RHOC/WASF2/ITGB5/CD47 11 GO:0014020 primary neural tube formation 7/435 94/18722 0.00629752143055846 0.133258247597432 SPINT2/SPINT1/LMO4/FOLR1/BMP7/RPS7/LRP2 7 GO:0042391 regulation of membrane potential 19/435 434/18722 0.00647870765775694 0.136363011711405 IFI6/SOD1/DSP/HEBP2/ARL6IP5/PARP1/APP/GJA1/CLN3/ADRB1/GJA5/DSC2/PARK7/BAD/STOML2/KCNN4/BNIP3/CAV1/S1PR2 19 GO:0016485 protein processing 12/435 225/18722 0.00655530167933508 0.137245125635603 PERP/CTSL/PARP1/MME/CLN3/PISD/BAD/STOML2/ASPH/SPCS1/TMEM59/LPCAT3 12 GO:0016264 gap junction assembly 3/435 17/18722 0.00664706374269179 0.137389950146477 GJA1/GJA5/CAV1 3 GO:0032048 cardiolipin metabolic process 3/435 17/18722 0.00664706374269179 0.137389950146477 STOML2/DNAJC19/HADHA 3 GO:0036473 cell death in response to oxidative stress 7/435 95/18722 0.00666638120498449 0.137389950146477 PAGE4/SOD1/P4HB/ARL6IP5/MET/PARP1/PARK7 7 GO:0072659 protein localization to plasma membrane 14/435 284/18722 0.00686532335676427 0.140756914625473 KRT18/ANXA2/EGFR/BSG/CDH1/VAMP8/TMEM150A/ARL6IP5/CLN3/S100A10/LGALS3/NSG1/TMEM59/LAMA5 14 GO:0048048 embryonic eye morphogenesis 4/435 33/18722 0.00690227371525578 0.140785036552923 EFEMP1/FBN2/BMP7/FBN1 4 GO:0051897 positive regulation of protein kinase B signaling 8/435 120/18722 0.00696997706225862 0.141436919155679 EGFR/LRP2/MET/HSP90AB1/PARK7/C1QBP/MYDGF/PHB 8 GO:0071559 response to transforming growth factor beta 13/435 256/18722 0.00710958114357375 0.142805140025997 PEG10/CDKN1C/FBN2/FOLR1/PARP1/FBN1/HSP90AB1/PDCD5/FERMT1/EID2/NREP/CAV1/ITGB5 13 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 13/435 256/18722 0.00710958114357375 0.142805140025997 PEG10/CDKN1C/FBN2/FOLR1/BMP7/LRP2/PARP1/FBN1/HSP90AB1/FERMT1/EID2/NREP/CAV1 13 GO:0016053 organic acid biosynthetic process 15/435 316/18722 0.00733610469518856 0.146610940802329 MGST3/GSTP1/DEGS1/SLC27A2/ACSS1/CLN3/ADI1/HACD3/PARK7/TECR/CDO1/NDUFAB1/ASS1/MIF/ACADVL 15 GO:0006801 superoxide metabolic process 6/435 74/18722 0.00744753179953582 0.146703464565249 GSTP1/SOD1/EGFR/PRDX1/BMP7/PRDX2 6 GO:1903201 regulation of oxidative stress-induced cell death 6/435 74/18722 0.00744753179953582 0.146703464565249 PAGE4/SOD1/P4HB/MET/PARP1/PARK7 6 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 7/435 97/18722 0.00745195763902325 0.146703464565249 IFI6/ITGA6/GSTP1/PRDX2/PARK7/LGALS3/LMNA 7 GO:0007584 response to nutrient 10/435 174/18722 0.00762492346495698 0.147556889027891 GSTP1/EGFR/FOLR1/BMP7/SLC6A4/AGL/ASS1/COX4I1/ATP2B1/CCND1 10 GO:0072329 monocarboxylic acid catabolic process 8/435 122/18722 0.00767610174596131 0.147556889027891 ECHS1/ECH1/SLC27A2/ECI2/ECI1/ACADVL/ETFA/HADHA 8 GO:0000096 sulfur amino acid metabolic process 4/435 34/18722 0.00768175869086318 0.147556889027891 COMT/SMS/ADI1/CDO1 4 GO:0007431 salivary gland development 4/435 34/18722 0.00768175869086318 0.147556889027891 BMP7/TGM2/DAG1/LAMA5 4 GO:0086004 regulation of cardiac muscle cell contraction 4/435 34/18722 0.00768175869086318 0.147556889027891 DSP/GJA5/DSC2/CAV1 4 GO:0031667 response to nutrient levels 20/435 474/18722 0.00783482227016496 0.149709041589359 PAGE4/KRT18/GSTP1/SOD1/EGFR/SLC2A1/COMT/FOLR1/BMP7/NENF/ADRB1/SLC6A4/AGL/ASS1/COX4I1/FIS1/ATP2B1/BNIP3/CCND1/TXN2 20 GO:1902882 regulation of response to oxidative stress 7/435 98/18722 0.00786946693216746 0.149709041589359 PAGE4/SOD1/BMP7/P4HB/MET/PARP1/PARK7 7 GO:0001667 ameboidal-type cell migration 20/435 475/18722 0.00800896908572433 0.151633926661297 SERPINF1/NRP2/FOLR1/BMP7/ANXA3/MET/PDLIM1/GJA1/CLN3/ITGB4/EFNA1/NR2F2/C1QBP/CALR/FERMT1/AMOT/LAMA5/TACSTD2/WASF2/PDCD6 20 GO:0010811 positive regulation of cell-substrate adhesion 8/435 123/18722 0.00804871014890368 0.151660695520056 ITGA6/P4HB/S100A10/C1QBP/DAG1/CALR/FERMT1/CCDC80 8 GO:0086002 cardiac muscle cell action potential involved in contraction 5/435 54/18722 0.00822331164959235 0.154216323210601 DSP/GJA1/GJA5/DSC2/CAV1 5 GO:0071383 cellular response to steroid hormone stimulus 11/435 204/18722 0.00836188419993351 0.156075357448759 SERPINF1/GSTP1/EGFR/BMP7/PARP1/PARK7/CALR/ASS1/PHB/ATP2B1/SKP2 11 GO:2000379 positive regulation of reactive oxygen species metabolic process 6/435 76/18722 0.00845705050967399 0.15711055806 GSTP1/SOD1/EGFR/DCXR/ROMO1/PARK7 6 GO:0045907 positive regulation of vasoconstriction 4/435 35/18722 0.00851696076082802 0.157484176311199 EGFR/GJA1/GJA5/CAV1 4 GO:0036293 response to decreased oxygen levels 15/435 322/18722 0.00864315569843759 0.15907426557543 CD24/SLC2A1/BMP7/P4HB/PDLIM1/HSPD1/HSP90B1/SLC6A4/HILPDA/BAD/LMNA/FIS1/BNIP3/CAV1/TXN2 15 GO:0003018 vascular process in circulatory system 13/435 263/18722 0.00881407899281159 0.161469030437757 SOD1/EGFR/SLC2A1/LRP2/GJA1/ADRB1/GJA5/SLC6A4/SLC13A3/ATP2B1/SLC19A1/CAV1/SLC1A5 13 GO:0035461 vitamin transmembrane transport 3/435 19/18722 0.0091524471376297 0.166895084440556 FOLR1/LRP2/SLC19A1 3 GO:0090322 regulation of superoxide metabolic process 4/435 36/18722 0.0094093938604172 0.17002365710252 GSTP1/SOD1/EGFR/BMP7 4 GO:0046395 carboxylic acid catabolic process 12/435 236/18722 0.00940995221264892 0.17002365710252 GCSH/ECHS1/ECH1/QPRT/SLC27A2/GLDC/ECI2/ECI1/CDO1/ACADVL/ETFA/HADHA 12 GO:0048660 regulation of smooth muscle cell proliferation 10/435 180/18722 0.00956451129640375 0.171285139662767 GSTP1/EGFR/COMT/TGM2/DNMT1/GJA1/AKR1B1/PHB/SKP2/S1PR2 10 GO:0071385 cellular response to glucocorticoid stimulus 5/435 56/18722 0.00956634214442041 0.171285139662767 SERPINF1/GSTP1/EGFR/ASS1/ATP2B1 5 GO:0001841 neural tube formation 7/435 102/18722 0.00971352657828623 0.173137048064318 SPINT2/SPINT1/LMO4/FOLR1/BMP7/RPS7/LRP2 7 GO:0051348 negative regulation of transferase activity 13/435 268/18722 0.0102167305520081 0.180874666579147 GSTP1/CDKN1C/PKIB/RPL37/MLLT1/RPL23/BMP7/RPS7/NR2F2/PARK7/NPM1/PHPT1/CAV1 13 GO:0031647 regulation of protein stability 14/435 298/18722 0.0102390511280589 0.180874666579147 PPIB/RPL23/RPS7/DDOST/SERF2/HSPD1/HSP90AB1/EFNA1/PARK7/CALR/LMNA/PHB/TBL1X/NPM1 14 GO:0050891 multicellular organismal water homeostasis 5/435 57/18722 0.0102912898066797 0.18098948340014 CLDN4/MET/AKR1B1/ATP6V1B1/LSR 5 GO:0045730 respiratory burst 4/435 37/18722 0.0103605016163259 0.181400464140714 CD24/RPS19/PRDX2/CD55 4 GO:0032930 positive regulation of superoxide anion generation 3/435 20/18722 0.0105846951617147 0.184509421827776 GSTP1/SOD1/EGFR 3 GO:0016054 organic acid catabolic process 12/435 240/18722 0.0106591834651556 0.184992934086056 GCSH/ECHS1/ECH1/QPRT/SLC27A2/GLDC/ECI2/ECI1/CDO1/ACADVL/ETFA/HADHA 12 GO:0048661 positive regulation of smooth muscle cell proliferation 7/435 104/18722 0.0107454585061413 0.185675892178171 EGFR/TGM2/DNMT1/GJA1/AKR1B1/PHB/SKP2 7 GO:0043467 regulation of generation of precursor metabolites and energy 8/435 130/18722 0.0110486789882444 0.186910099620037 PHLDA2/APP/NDUFA4/CISD1/IL10RB/COX7A2/PARK7/BNIP3 8 GO:0018208 peptidyl-proline modification 5/435 58/18722 0.0110529888553623 0.186910099620037 PPIB/P4HB/PRDX4/FKBP3/FKBP2 5 GO:0032387 negative regulation of intracellular transport 5/435 58/18722 0.0110529888553623 0.186910099620037 PARK7/LMAN1/FERMT1/SNX3/ERLEC1 5 GO:0086065 cell communication involved in cardiac conduction 5/435 58/18722 0.0110529888553623 0.186910099620037 DSP/GJA1/GJA5/DSC2/CAV1 5 GO:0048659 smooth muscle cell proliferation 10/435 184/18722 0.0110530612360598 0.186910099620037 GSTP1/EGFR/COMT/TGM2/DNMT1/GJA1/AKR1B1/PHB/SKP2/S1PR2 10 GO:0030198 extracellular matrix organization 14/435 301/18722 0.0111076861391763 0.187034527883918 SPINT2/SPINT1/ANXA2/VWA1/FBLN1/PRDX4/COL14A1/APP/ADAMTSL4/DAG1/ADAMTS6/FERMT1/CAV1/CCDC80 14 GO:0051017 actin filament bundle assembly 9/435 157/18722 0.0112512477143721 0.188649098329536 MET/PDLIM1/HSP90B1/S100A10/TACSTD2/RHOC/WASF2/ITGB5/CD47 9 GO:0007007 inner mitochondrial membrane organization 4/435 38/18722 0.0113716560121533 0.188802261826598 TIMM13/NDUFA13/ROMO1/TIMM8B 4 GO:0071260 cellular response to mechanical stimulus 6/435 81/18722 0.0114044158100857 0.188802261826598 EGFR/SLC2A1/GJA1/DAG1/BAD/BNIP3 6 GO:0043062 extracellular structure organization 14/435 302/18722 0.0114096849938063 0.188802261826598 SPINT2/SPINT1/ANXA2/VWA1/FBLN1/PRDX4/COL14A1/APP/ADAMTSL4/DAG1/ADAMTS6/FERMT1/CAV1/CCDC80 14 GO:0051896 regulation of protein kinase B signaling 10/435 185/18722 0.0114512365019923 0.188802261826598 EGFR/LRP2/MET/HSP90AB1/PARK7/C1QBP/MYDGF/DAG1/PHB/PDCD6 10 GO:0046683 response to organophosphorus 8/435 131/18722 0.011536647813274 0.189421225714213 SOD1/BSG/HSPD1/APP/HSP90B1/SLC6A4/CDO1/ASS1 8 GO:0044242 cellular lipid catabolic process 11/435 214/18722 0.0117015084466158 0.190034206943568 ECHS1/ECH1/SLC27A2/ECI2/IDH1/PRDX6/ECI1/FUCA1/ACADVL/ETFA/HADHA 11 GO:0015849 organic acid transport 14/435 303/18722 0.0117180557225754 0.190034206943568 SLC2A1/FOLR1/SLC27A2/LRP2/ARL6IP5/GJA1/CLN3/SLC13A3/SLC43A2/MPC2/FIS1/SLC38A9/SLC19A1/SLC1A5 14 GO:0051222 positive regulation of protein transport 14/435 303/18722 0.0117180557225754 0.190034206943568 EGFR/CDH1/WLS/GJA1/CLN3/BCAP31/HSP90AB1/MYH10/PDCD5/MPC2/BAD/FIS1/KCNN4/PHPT1 14 GO:0045229 external encapsulating structure organization 14/435 304/18722 0.0120328856268617 0.191375689041443 SPINT2/SPINT1/ANXA2/VWA1/FBLN1/PRDX4/COL14A1/APP/ADAMTSL4/DAG1/ADAMTS6/FERMT1/CAV1/CCDC80 14 GO:0001892 embryonic placenta development 6/435 82/18722 0.0120709431597449 0.191375689041443 SPINT2/SPINT1/PHLDA2/BMP7/KRT8/NR2F2 6 GO:0033762 response to glucagon 3/435 21/18722 0.0121393222010114 0.191375689041443 CDO1/ASS1/CYC1 3 GO:0045056 transcytosis 3/435 21/18722 0.0121393222010114 0.191375689041443 LRPAP1/LRP2/RAB17 3 GO:0070584 mitochondrion morphogenesis 3/435 21/18722 0.0121393222010114 0.191375689041443 SLIRP/SSBP1/FIS1 3 GO:1903427 negative regulation of reactive oxygen species biosynthetic process 3/435 21/18722 0.0121393222010114 0.191375689041443 PAGE4/HSPD1/PARK7 3 GO:2000178 negative regulation of neural precursor cell proliferation 3/435 21/18722 0.0121393222010114 0.191375689041443 SPINT2/SPINT1/SLC6A4 3 GO:0008637 apoptotic mitochondrial changes 7/435 107/18722 0.0124394427025813 0.194630539607464 IFI6/HSPD1/PDCD5/BAD/LMNA/FIS1/BNIP3 7 GO:1903115 regulation of actin filament-based movement 4/435 39/18722 0.0124441563105101 0.194630539607464 DSP/GJA5/DSC2/CAV1 4 GO:0031397 negative regulation of protein ubiquitination 6/435 83/18722 0.0127644152518112 0.19807369078987 RPL37/RPL23/RPS7/RPS3/PARK7/CAV1 6 GO:0048678 response to axon injury 6/435 83/18722 0.0127644152518112 0.19807369078987 SOD1/FOLR1/DAG1/NREP/BNIP3/TXN2 6 GO:0061572 actin filament bundle organization 9/435 161/18722 0.0131029593255027 0.202532851761774 MET/PDLIM1/HSP90B1/S100A10/TACSTD2/RHOC/WASF2/ITGB5/CD47 9 GO:0007568 aging 15/435 339/18722 0.0133699519753463 0.204308007788639 SERPINF1/SOD1/MME/APP/ROMO1/RPN2/HMGA1/DAG1/YPEL3/CALR/ASS1/LMNA/MIF/ATP2B1/NPM1 15 GO:0006970 response to osmotic stress 6/435 84/18722 0.0134853564023019 0.204308007788639 EGFR/SLC2A1/CLN3/HSP90AB1/AKR1B1/BAD 6 GO:0042310 vasoconstriction 6/435 84/18722 0.0134853564023019 0.204308007788639 EGFR/GJA1/GJA5/SLC6A4/ATP2B1/CAV1 6 GO:0006900 vesicle budding from membrane 5/435 61/18722 0.013566707385213 0.204308007788639 ANXA2/TMED9/S100A10/SNX3/PDCD6 5 GO:0034113 heterotypic cell-cell adhesion 5/435 61/18722 0.013566707385213 0.204308007788639 PERP/BMP7/DSP/DSC2/CD47 5 GO:0071384 cellular response to corticosteroid stimulus 5/435 61/18722 0.013566707385213 0.204308007788639 SERPINF1/GSTP1/EGFR/ASS1/ATP2B1 5 GO:0030501 positive regulation of bone mineralization 4/435 40/18722 0.0135792282154188 0.204308007788639 FBN2/BMP7/ATRAID/ATP2B1 4 GO:0032891 negative regulation of organic acid transport 3/435 22/18722 0.0138179014748446 0.205554271187819 ARL6IP5/SLC43A2/FIS1 3 GO:0060713 labyrinthine layer morphogenesis 3/435 22/18722 0.0138179014748446 0.205554271187819 SPINT2/SPINT1/BMP7 3 GO:0071359 cellular response to dsRNA 3/435 22/18722 0.0138179014748446 0.205554271187819 COLEC12/NPM1/CAV1 3 GO:0050856 regulation of T cell receptor signaling pathway 4/435 41/18722 0.0147780232594408 0.215367443653476 RPS3/LGALS3/KCNN4/PHPT1 4 GO:0071470 cellular response to osmotic stress 4/435 41/18722 0.0147780232594408 0.215367443653476 SLC2A1/CLN3/AKR1B1/BAD 4 GO:0071634 regulation of transforming growth factor beta production 4/435 41/18722 0.0147780232594408 0.215367443653476 CD24/HSP90AB1/FERMT1/CD46 4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 4/435 41/18722 0.0147780232594408 0.215367443653476 P4HB/S100A10/C1QBP/CALR 4 GO:0045471 response to ethanol 8/435 137/18722 0.0148041305720863 0.215367443653476 GSTP1/SOD1/RPL10A/GGH/CDO1/BAD/TUFM/CCND1 8 GO:0050714 positive regulation of protein secretion 8/435 137/18722 0.0148041305720863 0.215367443653476 EGFR/WLS/GJA1/MYH10/MPC2/BAD/KCNN4/PHPT1 8 GO:0010951 negative regulation of endopeptidase activity 12/435 252/18722 0.0151847772226809 0.219653848494807 SERPINF1/IFI6/SPINT2/SPINT1/ITIH5/PRDX5/PEBP1/ANXA2/APP/PARK7/APLP2/LAMTOR5 12 GO:0044282 small molecule catabolic process 16/435 376/18722 0.0152097939063879 0.219653848494807 GCSH/ECHS1/ECH1/QPRT/SLC27A2/GLDC/ECI2/PNP/ADH5/ECI1/PARK7/CDO1/BAD/ACADVL/ETFA/HADHA 16 GO:0050854 regulation of antigen receptor-mediated signaling pathway 5/435 63/18722 0.0154407621399288 0.220767500695605 RPS3/SLC39A10/LGALS3/KCNN4/PHPT1 5 GO:2000242 negative regulation of reproductive process 5/435 63/18722 0.0154407621399288 0.220767500695605 SERPINF1/BMP7/PRDX4/GJA1/CALR 5 GO:0006605 protein targeting 14/435 314/18722 0.0155557604781351 0.220767500695605 TIMM13/NDUFA13/HSPD1/BCAP31/ROMO1/TIMM8B/PDCD5/SRP14/LMAN1/FIS1/SPCS1/SIL1/DNAJC19/SSR2 14 GO:0046394 carboxylic acid biosynthetic process 14/435 314/18722 0.0155557604781351 0.220767500695605 MGST3/GSTP1/DEGS1/SLC27A2/ACSS1/CLN3/ADI1/HACD3/PARK7/TECR/NDUFAB1/ASS1/MIF/ACADVL 14 GO:0097305 response to alcohol 12/435 253/18722 0.0156189883334818 0.220767500695605 GSTP1/SOD1/CDH1/RPL10A/PARP1/GGH/CDO1/DAG1/BAD/TUFM/ATP2B1/CCND1 12 GO:1904666 regulation of ubiquitin protein ligase activity 3/435 23/18722 0.0156216830145142 0.220767500695605 RPL37/RPL23/RPS7 3 GO:1901222 regulation of NIK/NF-kappaB signaling 7/435 112/18722 0.0156774495060564 0.220767500695605 EGFR/PRDX1/BMP7/APP/RPS3/CALR/PHB 7 GO:1900182 positive regulation of protein localization to nucleus 6/435 87/18722 0.0158181039039298 0.221958287758334 CDH1/PARP1/HSP90AB1/PARK7/LAMTOR5/NPM1 6 GO:0090317 negative regulation of intracellular protein transport 4/435 42/18722 0.0160416184007038 0.224299236790053 PARK7/LMAN1/FERMT1/ERLEC1 4 GO:0070482 response to oxygen levels 15/435 347/18722 0.016195697584821 0.225656251208228 CD24/SLC2A1/BMP7/P4HB/PDLIM1/HSPD1/HSP90B1/SLC6A4/HILPDA/BAD/LMNA/FIS1/BNIP3/CAV1/TXN2 15 GO:0044106 cellular amine metabolic process 7/435 113/18722 0.0163905578483012 0.227450799563537 COMT/SMS/ALDH7A1/CLN3/PARK7/AKR1B1/LY6E 7 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process 5/435 64/18722 0.0164394563242789 0.227450799563537 RPL23/RPS7/HSP90AB1/EFNA1/PARK7 5 GO:0001843 neural tube closure 6/435 88/18722 0.0166539833401215 0.228818791933544 SPINT2/SPINT1/LMO4/FOLR1/RPS7/LRP2 6 GO:0010232 vascular transport 6/435 88/18722 0.0166539833401215 0.228818791933544 SLC2A1/LRP2/GJA1/SLC13A3/SLC19A1/SLC1A5 6 GO:0035296 regulation of tube diameter 8/435 141/18722 0.0173262701557364 0.232791125280614 SOD1/EGFR/GJA1/ADRB1/GJA5/SLC6A4/ATP2B1/CAV1 8 GO:0097746 blood vessel diameter maintenance 8/435 141/18722 0.0173262701557364 0.232791125280614 SOD1/EGFR/GJA1/ADRB1/GJA5/SLC6A4/ATP2B1/CAV1 8 GO:0071604 transforming growth factor beta production 4/435 43/18722 0.0173710158157125 0.232791125280614 CD24/HSP90AB1/FERMT1/CD46 4 GO:0098657 import into cell 11/435 227/18722 0.0174601516028509 0.232791125280614 SLC2A1/FOLR1/SLC27A2/LRP2/ARL6IP5/SLC6A4/SLC39A10/PARK7/SLC43A2/SLC19A1/SLC1A5 11 GO:0006487 protein N-linked glycosylation 5/435 65/18722 0.0174801793795451 0.232791125280614 TUSC3/DDOST/RPN2/OSTC/TMEM258 5 GO:0071677 positive regulation of mononuclear cell migration 5/435 65/18722 0.0174801793795451 0.232791125280614 APP/C1QBP/LGALS3/CALR/CD47 5 GO:0060606 tube closure 6/435 89/18722 0.0175198137058841 0.232791125280614 SPINT2/SPINT1/LMO4/FOLR1/RPS7/LRP2 6 GO:0032928 regulation of superoxide anion generation 3/435 24/18722 0.0175516119892197 0.232791125280614 GSTP1/SOD1/EGFR 3 GO:0090343 positive regulation of cell aging 3/435 24/18722 0.0175516119892197 0.232791125280614 HMGA1/YPEL3/LMNA 3 GO:2000679 positive regulation of transcription regulatory region DNA binding 3/435 24/18722 0.0175516119892197 0.232791125280614 PARP1/PARK7/LAMTOR5 3 GO:1904951 positive regulation of establishment of protein localization 14/435 319/18722 0.017590231604474 0.232791125280614 EGFR/CDH1/WLS/GJA1/CLN3/BCAP31/HSP90AB1/MYH10/PDCD5/MPC2/BAD/FIS1/KCNN4/PHPT1 14 GO:0035150 regulation of tube size 8/435 142/18722 0.0180022648857617 0.236661003830429 SOD1/EGFR/GJA1/ADRB1/GJA5/SLC6A4/ATP2B1/CAV1 8 GO:0050729 positive regulation of inflammatory response 8/435 142/18722 0.0180022648857617 0.236661003830429 EGFR/VAMP8/TGM2/RPS19/HSPD1/APP/PARK7/CD47 8 GO:0034504 protein localization to nucleus 13/435 290/18722 0.0185591746211967 0.242429424644889 MAGED1/CDH1/RPL23/BMP7/PARP1/HSP90AB1/PARK7/CALR/LMNA/FERMT1/LAMTOR5/TRIM29/NPM1 13 GO:0019229 regulation of vasoconstriction 5/435 66/18722 0.0185635874822849 0.242429424644889 EGFR/GJA1/GJA5/ATP2B1/CAV1 5 GO:0043200 response to amino acid 7/435 116/18722 0.0186672614004058 0.24298142553094 GSTP1/DNMT1/CDO1/BAD/ASS1/LAMTOR5/SLC38A9 7 GO:0045216 cell-cell junction organization 10/435 200/18722 0.0188132072551121 0.244078233142553 CLDN4/PERP/CDH1/DSP/GJA1/GJA5/CLDN7/CAV1/RHOC/LSR 10 GO:0015711 organic anion transport 15/435 354/18722 0.019027007318004 0.246045320122032 SLC2A1/FOLR1/LRP2/ARL6IP5/SLC22A11/GJA1/CLN3/SLC13A3/SLC43A2/MPC2/CYB5R1/SLC38A9/SLC19A1/CD47/SLC1A5 15 GO:0051492 regulation of stress fiber assembly 6/435 91/18722 0.0193431776531157 0.247102631082858 MET/S100A10/TACSTD2/RHOC/WASF2/CD47 6 GO:1903828 negative regulation of cellular protein localization 7/435 117/18722 0.0194730916240096 0.247102631082858 MAGED1/PARK7/LMAN1/FERMT1/TMEM59/TRIM29/ERLEC1 7 GO:0016540 protein autoprocessing 3/435 25/18722 0.0196083462623244 0.247102631082858 CTSL/PARP1/PISD 3 GO:0033119 negative regulation of RNA splicing 3/435 25/18722 0.0196083462623244 0.247102631082858 C1QBP/RPS26/NPM1 3 GO:0060706 cell differentiation involved in embryonic placenta development 3/435 25/18722 0.0196083462623244 0.247102631082858 SPINT2/KRT8/NR2F2 3 GO:0061436 establishment of skin barrier 3/435 25/18722 0.0196083462623244 0.247102631082858 CLDN4/MET/LSR 3 GO:0086064 cell communication by electrical coupling involved in cardiac conduction 3/435 25/18722 0.0196083462623244 0.247102631082858 GJA1/GJA5/CAV1 3 GO:1901798 positive regulation of signal transduction by p53 class mediator 3/435 25/18722 0.0196083462623244 0.247102631082858 RPL37/RPL23/RPS7 3 GO:0010466 negative regulation of peptidase activity 12/435 262/18722 0.0199614400443197 0.250652907040209 SERPINF1/IFI6/SPINT2/SPINT1/ITIH5/PRDX5/PEBP1/ANXA2/APP/PARK7/APLP2/LAMTOR5 12 GO:0051099 positive regulation of binding 9/435 173/18722 0.0200167598242876 0.250652907040209 ANXA2/MET/PARP1/APP/HSP90AB1/S100A10/PARK7/LAMTOR5/CAV1 9 GO:0051180 vitamin transport 4/435 45/18722 0.0202308522854005 0.252082520713861 SLC2A1/FOLR1/LRP2/SLC19A1 4 GO:0009308 amine metabolic process 7/435 118/18722 0.0203029404193834 0.252082520713861 COMT/SMS/ALDH7A1/CLN3/PARK7/AKR1B1/LY6E 7 GO:0042060 wound healing 17/435 422/18722 0.0203857484529784 0.252082520713861 CLDN4/ANXA2/EGFR/F5/FBLN1/DSP/PRDX2/CD59/GNAS/GJA1/ANXA5/DAG1/LMAN1/FERMT1/TNFRSF12A/CAV1/RHOC 17 GO:0072594 establishment of protein localization to organelle 17/435 422/18722 0.0203857484529784 0.252082520713861 CDH1/RPL23/TIMM13/NDUFA13/HSPD1/BCAP31/HSP90AB1/ROMO1/TIMM8B/PDCD5/SRP14/LMAN1/LMNA/FERMT1/FIS1/SPCS1/DNAJC19 17 GO:0033273 response to vitamin 6/435 93/18722 0.0212917819390315 0.258179715795198 GSTP1/EGFR/FOLR1/BMP7/ATP2B1/CCND1 6 GO:0045185 maintenance of protein location 6/435 93/18722 0.0212917819390315 0.258179715795198 FBN2/GJA1/FBN1/PARK7/KDELR1/CAV1 6 GO:0002934 desmosome organization 2/435 10/18722 0.0214232400148219 0.258179715795198 PERP/DSP 2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 2/435 10/18722 0.0214232400148219 0.258179715795198 P4HB/PRDX4 2 GO:0032025 response to cobalt ion 2/435 10/18722 0.0214232400148219 0.258179715795198 SERPINF1/BNIP3 2 GO:0032070 regulation of deoxyribonuclease activity 2/435 10/18722 0.0214232400148219 0.258179715795198 RPS3/NPM1 2 GO:0051409 response to nitrosative stress 2/435 10/18722 0.0214232400148219 0.258179715795198 ADH5/PARK7 2 GO:2000510 positive regulation of dendritic cell chemotaxis 2/435 10/18722 0.0214232400148219 0.258179715795198 C1QBP/CALR 2 GO:0048193 Golgi vesicle transport 13/435 296/18722 0.0215422907176003 0.258179715795198 KRT18/TMED4/CLN3/BCAP31/ERGIC3/TMED9/LMAN1/YIF1A/KDELR1/SNX3/TMED1/PDCD6/SCAMP2 13 GO:0016331 morphogenesis of embryonic epithelium 8/435 147/18722 0.0216680121825638 0.258179715795198 SPINT2/SPINT1/LMO4/FOLR1/BMP7/RPS7/LRP2/LAMA5 8 GO:0006760 folic acid-containing compound metabolic process 3/435 26/18722 0.021792273205862 0.258179715795198 FOLR1/GGH/SLC19A1 3 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 3/435 26/18722 0.021792273205862 0.258179715795198 RPS3/SLC39A10/KCNN4 3 GO:0060669 embryonic placenta morphogenesis 3/435 26/18722 0.021792273205862 0.258179715795198 SPINT2/SPINT1/BMP7 3 GO:0097066 response to thyroid hormone 3/435 26/18722 0.021792273205862 0.258179715795198 CTSL/ANXA2/AKR1B1 3 GO:0034605 cellular response to heat 5/435 69/18722 0.0220760859292037 0.25998533339839 HSPD1/HSP90AB1/RBBP7/PDCD6/HSBP1L1 5 GO:1901224 positive regulation of NIK/NF-kappaB signaling 5/435 69/18722 0.0220760859292037 0.25998533339839 EGFR/APP/RPS3/CALR/PHB 5 GO:0014074 response to purine-containing compound 8/435 148/18722 0.0224600777783743 0.262942389849192 SOD1/BSG/HSPD1/APP/HSP90B1/SLC6A4/CDO1/ASS1 8 GO:0035148 tube formation 8/435 148/18722 0.0224600777783743 0.262942389849192 SPINT2/SPINT1/LMO4/FOLR1/BMP7/RPS7/LRP2/TGM2 8 GO:0048738 cardiac muscle tissue development 11/435 236/18722 0.0225353090898505 0.263044891057635 BMP7/DSP/LRP2/GJA1/GJA5/MSX2/LY6E/CALR/LMNA/NDUFV2/PRMT1 11 GO:0010720 positive regulation of cell development 13/435 298/18722 0.0226121558044994 0.263165589760012 SERPINF1/SPINT1/EGFR/P4HB/LRP2/TGM2/MME/S100A10/C1QBP/DAG1/CALR/BAD/S1PR2 13 GO:0001838 embryonic epithelial tube formation 7/435 121/18722 0.0229398020273647 0.266195884522822 SPINT2/SPINT1/LMO4/FOLR1/BMP7/RPS7/LRP2 7 GO:0031589 cell-substrate adhesion 15/435 363/18722 0.0232037132512015 0.267257855469918 ITGA6/FBLN1/P4HB/BCAM/ITGB4/S100A10/EFNA1/C1QBP/DAG1/CALR/FERMT1/LAMA5/TACSTD2/ITGB5/CCDC80 15 GO:0071214 cellular response to abiotic stimulus 14/435 331/18722 0.0232964042600832 0.267257855469918 ADIRF/EGFR/SLC2A1/PARP1/MME/GJA1/CLN3/AKR1B1/DAG1/GTF2H5/BAD/NPM1/DDB1/BNIP3 14 GO:0104004 cellular response to environmental stimulus 14/435 331/18722 0.0232964042600832 0.267257855469918 ADIRF/EGFR/SLC2A1/PARP1/MME/GJA1/CLN3/AKR1B1/DAG1/GTF2H5/BAD/NPM1/DDB1/BNIP3 14 GO:0009410 response to xenobiotic stimulus 18/435 462/18722 0.0233277361866349 0.267257855469918 ADIRF/GSTP1/SOD1/EGFR/COMT/CDH1/HSPD1/PNP/HSP90AB1/SLC6A4/RPN2/GGH/S100A10/CALR/BAD/ASS1/HADHA/TXN2 18 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 6/435 95/18722 0.0233690214790477 0.267257855469918 RPL37/RPL23/RPS7/RPS3/PARK7/CAV1 6 GO:0009266 response to temperature stimulus 9/435 178/18722 0.0235613326790467 0.268680672654143 SOD1/HSPD1/ADRB1/HSP90AB1/ACADVL/RBBP7/ATP2B1/PDCD6/HSBP1L1 9 GO:0000027 ribosomal large subunit assembly 3/435 27/18722 0.0241035258002585 0.271731201115735 RPLP0/RPL23A/MRPL20 3 GO:0008053 mitochondrial fusion 3/435 27/18722 0.0241035258002585 0.271731201115735 FIS1/STOML2/BNIP3 3 GO:0018126 protein hydroxylation 3/435 27/18722 0.0241035258002585 0.271731201115735 P4HB/PRDX4/ASPH 3 GO:0033561 regulation of water loss via skin 3/435 27/18722 0.0241035258002585 0.271731201115735 CLDN4/MET/LSR 3 GO:0010769 regulation of cell morphogenesis involved in differentiation 6/435 96/18722 0.02445688550334 0.273378237109368 FBLN1/P4HB/S100A10/C1QBP/CALR/TACSTD2 6 GO:0043648 dicarboxylic acid metabolic process 6/435 96/18722 0.02445688550334 0.273378237109368 FOLR1/QPRT/IDH1/ASS1/SLC19A1/MDH2 6 GO:1901655 cellular response to ketone 6/435 96/18722 0.02445688550334 0.273378237109368 SERPINF1/EGFR/PARK7/AKR1B1/ASS1/ATP2B1 6 GO:0072001 renal system development 13/435 302/18722 0.024869848083677 0.276523138039911 SERPINF1/CD24/MAGED1/BMP7/LRP2/MME/FBN1/LGR5/AKR1B1/ADAMTS6/ASS1/LAMA5/TACSTD2 13 GO:0090199 regulation of release of cytochrome c from mitochondria 4/435 48/18722 0.0250348891426786 0.276523138039911 PDCD5/BAD/LMNA/BNIP3 4 GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 4/435 48/18722 0.0250348891426786 0.276523138039911 RPL23/RPS7/HSP90AB1/PARK7 4 GO:0043409 negative regulation of MAPK cascade 9/435 180/18722 0.0250973521621754 0.276523138039911 PEBP1/GSTP1/DUSP9/FBLN1/BMP7/EFNA1/DAG1/PHB/CAV1 9 GO:0140694 non-membrane-bounded organelle assembly 15/435 367/18722 0.0252669521432882 0.276523138039911 RPS14/RPS27/RPS28/RPS23/RPS5/RPLP0/RPS19/KRT8/RPL23A/CSRP2/RPSA/RPS3/C1QBP/MRPL20/NPM1 15 GO:0031396 regulation of protein ubiquitination 10/435 210/18722 0.0253529340549812 0.276523138039911 RPL37/RPL23/RPS7/HSP90AB1/RPS3/PARK7/NPM1/SKP2/CAV1/PDCD6 10 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 2/435 11/18722 0.0257864639718795 0.276523138039911 CD46/CD55 2 GO:0003093 regulation of glomerular filtration 2/435 11/18722 0.0257864639718795 0.276523138039911 GJA1/GJA5 2 GO:0003174 mitral valve development 2/435 11/18722 0.0257864639718795 0.276523138039911 GJA5/EFNA1 2 GO:0010918 positive regulation of mitochondrial membrane potential 2/435 11/18722 0.0257864639718795 0.276523138039911 BAD/STOML2 2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway 2/435 11/18722 0.0257864639718795 0.276523138039911 PARP1/SKP2 2 GO:0033483 gas homeostasis 2/435 11/18722 0.0257864639718795 0.276523138039911 GSTP1/CAV1 2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase 2/435 11/18722 0.0257864639718795 0.276523138039911 ACADVL/ETFA 2 GO:0043589 skin morphogenesis 2/435 11/18722 0.0257864639718795 0.276523138039911 ITGA6/ITGB4 2 GO:0106049 regulation of cellular response to osmotic stress 2/435 11/18722 0.0257864639718795 0.276523138039911 CLN3/BAD 2 GO:0033627 cell adhesion mediated by integrin 5/435 72/18722 0.0259937914591784 0.276528075770858 ITGB4/FBN1/EFNA1/FERMT1/ITGB5 5 GO:0043903 regulation of biological process involved in symbiotic interaction 5/435 72/18722 0.0259937914591784 0.276528075770858 P4HB/LY6E/SNX3/DDB1/CAV1 5 GO:0043491 protein kinase B signaling 10/435 211/18722 0.0260865081076282 0.276528075770858 EGFR/LRP2/MET/HSP90AB1/PARK7/C1QBP/MYDGF/DAG1/PHB/PDCD6 10 GO:0000470 maturation of LSU-rRNA 3/435 28/18722 0.0265419980453496 0.276528075770858 RPL10A/RPL7A/NHP2 3 GO:0051503 adenine nucleotide transport 3/435 28/18722 0.0265419980453496 0.276528075770858 GJA1/SLC19A1/CD47 3 GO:0090200 positive regulation of release of cytochrome c from mitochondria 3/435 28/18722 0.0265419980453496 0.276528075770858 PDCD5/BAD/BNIP3 3 GO:0061138 morphogenesis of a branching epithelium 9/435 182/18722 0.0267031678497898 0.276528075770858 SPINT2/SPINT1/MAGED1/BMP7/TGM2/MET/DAG1/LAMA5/TACSTD2 9 GO:0061337 cardiac conduction 6/435 98/18722 0.0267329997083183 0.276528075770858 DSP/GJA1/GJA5/DSC2/ATP2B1/CAV1 6 GO:0006692 prostanoid metabolic process 4/435 49/18722 0.0267759753719849 0.276528075770858 GSTP1/AKR1B1/ATP6V1B1/MIF 4 GO:0006693 prostaglandin metabolic process 4/435 49/18722 0.0267759753719849 0.276528075770858 GSTP1/AKR1B1/ATP6V1B1/MIF 4 GO:0009409 response to cold 4/435 49/18722 0.0267759753719849 0.276528075770858 HSPD1/ADRB1/ACADVL/ATP2B1 4 GO:0045778 positive regulation of ossification 4/435 49/18722 0.0267759753719849 0.276528075770858 FBN2/BMP7/ATRAID/ATP2B1 4 GO:0052372 modulation by symbiont of entry into host 4/435 49/18722 0.0267759753719849 0.276528075770858 P4HB/LY6E/SNX3/CAV1 4 GO:0070169 positive regulation of biomineral tissue development 4/435 49/18722 0.0267759753719849 0.276528075770858 FBN2/BMP7/ATRAID/ATP2B1 4 GO:0030258 lipid modification 10/435 212/18722 0.0268351733879225 0.276528075770858 ECHS1/ECH1/SLC27A2/ECI2/ADH5/ECI1/ACADVL/ETFA/HADHA/LPCAT3 10 GO:0086003 cardiac muscle cell contraction 5/435 73/18722 0.0273920992565714 0.281533861709748 DSP/GJA1/GJA5/DSC2/CAV1 5 GO:0007605 sensory perception of sound 8/435 154/18722 0.0276450286216717 0.283397352994702 SOD1/NDUFB9/LRP2/ALDH7A1/TIMM13/TIMM8B/ATP6V1B1/TBL1X 8 GO:0072330 monocarboxylic acid biosynthetic process 10/435 214/18722 0.0283783715076291 0.287601215346925 GSTP1/DEGS1/SLC27A2/ACSS1/HACD3/PARK7/TECR/NDUFAB1/MIF/ACADVL 10 GO:0110151 positive regulation of biomineralization 4/435 50/18722 0.0285878030221789 0.287601215346925 FBN2/BMP7/ATRAID/ATP2B1 4 GO:0098656 anion transmembrane transport 11/435 245/18722 0.0286156939449578 0.287601215346925 FOLR1/LRP2/ARL6IP5/SLC25A3/GJA1/SLC13A3/SLC43A2/MPC2/SLC38A9/SLC19A1/SLC1A5 11 GO:0003151 outflow tract morphogenesis 5/435 74/18722 0.0288373577679508 0.287601215346925 NRP2/FOLR1/BMP7/LRP2/GJA5 5 GO:0010822 positive regulation of mitochondrion organization 5/435 74/18722 0.0288373577679508 0.287601215346925 PDCD5/PARK7/BAD/FIS1/BNIP3 5 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 5/435 74/18722 0.0288373577679508 0.287601215346925 PARP1/PARK7/CALR/PHB/SKP2 5 GO:0070972 protein localization to endoplasmic reticulum 5/435 74/18722 0.0288373577679508 0.287601215346925 GJA1/BCAP31/SRP14/KDELR1/SPCS1 5 GO:0030048 actin filament-based movement 7/435 127/18722 0.0289036404675807 0.287601215346925 DSP/GJA1/GJA5/MYH10/DSC2/CAV1/WASF2 7 GO:0015868 purine ribonucleotide transport 3/435 29/18722 0.0291073597079068 0.287601215346925 GJA1/SLC19A1/CD47 3 GO:0022011 myelination in peripheral nervous system 3/435 29/18722 0.0291073597079068 0.287601215346925 SOD1/ITGB4/DAG1 3 GO:0030970 retrograde protein transport, ER to cytosol 3/435 29/18722 0.0291073597079068 0.287601215346925 HSP90B1/BCAP31/ERLEC1 3 GO:0032292 peripheral nervous system axon ensheathment 3/435 29/18722 0.0291073597079068 0.287601215346925 SOD1/ITGB4/DAG1 3 GO:0071549 cellular response to dexamethasone stimulus 3/435 29/18722 0.0291073597079068 0.287601215346925 SERPINF1/EGFR/ASS1 3 GO:1903513 endoplasmic reticulum to cytosol transport 3/435 29/18722 0.0291073597079068 0.287601215346925 HSP90B1/BCAP31/ERLEC1 3 GO:0110020 regulation of actomyosin structure organization 6/435 100/18722 0.0291453341809747 0.287601215346925 MET/S100A10/TACSTD2/RHOC/WASF2/CD47 6 GO:0043627 response to estrogen 5/435 75/18722 0.0303299722554967 0.290576734016161 CD24/COMT/HSPD1/CCND1/CAV1 5 GO:0006576 cellular biogenic amine metabolic process 6/435 101/18722 0.0304034212825447 0.290576734016161 COMT/SMS/ALDH7A1/PARK7/AKR1B1/LY6E 6 GO:0007614 short-term memory 2/435 12/18722 0.0304749417782934 0.290576734016161 SERPINF1/COMT 2 GO:0009886 post-embryonic animal morphogenesis 2/435 12/18722 0.0304749417782934 0.290576734016161 EFEMP1/FBN1 2 GO:0046185 aldehyde catabolic process 2/435 12/18722 0.0304749417782934 0.290576734016161 ADH5/PARK7 2 GO:0048548 regulation of pinocytosis 2/435 12/18722 0.0304749417782934 0.290576734016161 CLN3/CAV1 2 GO:0061307 cardiac neural crest cell differentiation involved in heart development 2/435 12/18722 0.0304749417782934 0.290576734016161 FOLR1/BMP7 2 GO:0061308 cardiac neural crest cell development involved in heart development 2/435 12/18722 0.0304749417782934 0.290576734016161 FOLR1/BMP7 2 GO:0071635 negative regulation of transforming growth factor beta production 2/435 12/18722 0.0304749417782934 0.290576734016161 CD24/HSP90AB1 2 GO:0072584 caveolin-mediated endocytosis 2/435 12/18722 0.0304749417782934 0.290576734016161 CLN3/CAV1 2 GO:1901298 regulation of hydrogen peroxide-mediated programmed cell death 2/435 12/18722 0.0304749417782934 0.290576734016161 MET/PARK7 2 GO:1903599 positive regulation of autophagy of mitochondrion 2/435 12/18722 0.0304749417782934 0.290576734016161 PARK7/BNIP3 2 GO:2000105 positive regulation of DNA-dependent DNA replication 2/435 12/18722 0.0304749417782934 0.290576734016161 SSBP1/STOML2 2 GO:2000508 regulation of dendritic cell chemotaxis 2/435 12/18722 0.0304749417782934 0.290576734016161 C1QBP/CALR 2 GO:1990542 mitochondrial transmembrane transport 6/435 102/18722 0.0316965397015609 0.298134401225523 SLC25A3/HSPD1/ROMO1/MPC2/STOML2/DNAJC19 6 GO:0006099 tricarboxylic acid cycle 3/435 30/18722 0.0317990704300403 0.298134401225523 IDH1/SUCLG1/MDH2 3 GO:0006884 cell volume homeostasis 3/435 30/18722 0.0317990704300403 0.298134401225523 CLN3/KCNN4/NPM1 3 GO:0010800 positive regulation of peptidyl-threonine phosphorylation 3/435 30/18722 0.0317990704300403 0.298134401225523 BMP7/APP/S1PR2 3 GO:0015865 purine nucleotide transport 3/435 30/18722 0.0317990704300403 0.298134401225523 GJA1/SLC19A1/CD47 3 GO:1902751 positive regulation of cell cycle G2/M phase transition 3/435 30/18722 0.0317990704300403 0.298134401225523 APP/NPM1/CCND1 3 GO:0031100 animal organ regeneration 5/435 76/18722 0.0318703188573152 0.298134401225523 GSTP1/EGFR/RPS16/ANXA3/CCND1 5 GO:0086001 cardiac muscle cell action potential 5/435 76/18722 0.0318703188573152 0.298134401225523 DSP/GJA1/GJA5/DSC2/CAV1 5 GO:2000378 negative regulation of reactive oxygen species metabolic process 4/435 52/18722 0.0324252759965401 0.302610417731861 PAGE4/HSPD1/PARK7/BNIP3 4 GO:0003279 cardiac septum development 6/435 103/18722 0.033024984866583 0.307482035569573 LMO4/NRP2/BMP7/LRP2/GJA5/ADAMTS6 6 GO:0010810 regulation of cell-substrate adhesion 10/435 221/18722 0.0342761854827293 0.31191076047319 ITGA6/FBLN1/P4HB/S100A10/C1QBP/DAG1/CALR/FERMT1/TACSTD2/CCDC80 10 GO:0051438 regulation of ubiquitin-protein transferase activity 4/435 53/18722 0.0344515445147248 0.31191076047319 RPL37/RPL23/RPS7/PARK7 4 GO:0072175 epithelial tube formation 7/435 132/18722 0.0346117054325877 0.31191076047319 SPINT2/SPINT1/LMO4/FOLR1/BMP7/RPS7/LRP2 7 GO:0006613 cotranslational protein targeting to membrane 3/435 31/18722 0.0346163932220383 0.31191076047319 SRP14/SIL1/SSR2 3 GO:0033238 regulation of cellular amine metabolic process 3/435 31/18722 0.0346163932220383 0.31191076047319 COMT/CLN3/PARK7 3 GO:0036475 neuron death in response to oxidative stress 3/435 31/18722 0.0346163932220383 0.31191076047319 ARL6IP5/PARP1/PARK7 3 GO:0042133 neurotransmitter metabolic process 3/435 31/18722 0.0346163932220383 0.31191076047319 COMT/CLN3/SLC6A4 3 GO:0003205 cardiac chamber development 8/435 161/18722 0.0346780666113346 0.31191076047319 LMO4/NRP2/BMP7/DSP/LRP2/GJA5/ADAMTS6/LY6E 8 GO:0009743 response to carbohydrate 11/435 253/18722 0.0349396138938159 0.31191076047319 SERPINF1/KRT18/GSTP1/COLEC12/GJA1/MPC2/HMGN3/BAD/FIS1/PHPT1/TXN2 11 GO:0006264 mitochondrial DNA replication 2/435 13/18722 0.0354712767786039 0.31191076047319 SSBP1/STOML2 2 GO:0007183 SMAD protein complex assembly 2/435 13/18722 0.0354712767786039 0.31191076047319 PARP1/EID2 2 GO:0007494 midgut development 2/435 13/18722 0.0354712767786039 0.31191076047319 EGFR/ASS1 2 GO:0010958 regulation of amino acid import across plasma membrane 2/435 13/18722 0.0354712767786039 0.31191076047319 ARL6IP5/SLC43A2 2 GO:0015809 arginine transport 2/435 13/18722 0.0354712767786039 0.31191076047319 CLN3/SLC38A9 2 GO:0030497 fatty acid elongation 2/435 13/18722 0.0354712767786039 0.31191076047319 HACD3/TECR 2 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway 2/435 13/18722 0.0354712767786039 0.31191076047319 PARP1/SKP2 2 GO:0042761 very long-chain fatty acid biosynthetic process 2/435 13/18722 0.0354712767786039 0.31191076047319 HACD3/TECR 2 GO:0046415 urate metabolic process 2/435 13/18722 0.0354712767786039 0.31191076047319 SLC22A11/PNP 2 GO:0046689 response to mercury ion 2/435 13/18722 0.0354712767786039 0.31191076047319 BSG/PARK7 2 GO:0051956 negative regulation of amino acid transport 2/435 13/18722 0.0354712767786039 0.31191076047319 ARL6IP5/SLC43A2 2 GO:0060670 branching involved in labyrinthine layer morphogenesis 2/435 13/18722 0.0354712767786039 0.31191076047319 SPINT2/SPINT1 2 GO:0070254 mucus secretion 2/435 13/18722 0.0354712767786039 0.31191076047319 EGFR/VAMP8 2 GO:0098814 spontaneous synaptic transmission 2/435 13/18722 0.0354712767786039 0.31191076047319 APP/NSG1 2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding 2/435 13/18722 0.0354712767786039 0.31191076047319 ZNF593/LAMTOR5 2 GO:1903789 regulation of amino acid transmembrane transport 2/435 13/18722 0.0354712767786039 0.31191076047319 ARL6IP5/SLC43A2 2 GO:0032231 regulation of actin filament bundle assembly 6/435 105/18722 0.0357889634713173 0.31400649325056 MET/S100A10/TACSTD2/RHOC/WASF2/CD47 6 GO:0006584 catecholamine metabolic process 4/435 54/18722 0.0365498031439354 0.319266161237423 COMT/PARK7/AKR1B1/LY6E 4 GO:0009712 catechol-containing compound metabolic process 4/435 54/18722 0.0365498031439354 0.319266161237423 COMT/PARK7/AKR1B1/LY6E 4 GO:1903362 regulation of cellular protein catabolic process 11/435 255/18722 0.036663248064391 0.31955170174184 ANXA2/RPL23/RPS7/LRP2/BCAP31/HSP90AB1/EFNA1/PARK7/ATRAID/PSMC1/CAV1 11 GO:0006633 fatty acid biosynthetic process 8/435 163/18722 0.0368911902295328 0.320831735688486 GSTP1/DEGS1/ACSS1/HACD3/TECR/NDUFAB1/MIF/ACADVL 8 GO:0061041 regulation of wound healing 7/435 134/18722 0.0370902352572674 0.320990535492545 CLDN4/ANXA2/PRDX2/GJA1/FERMT1/TNFRSF12A/CAV1 7 GO:0090263 positive regulation of canonical Wnt signaling pathway 6/435 106/18722 0.037225013652739 0.320990535492545 RPS12/EGFR/WLS/LGR5/TBL1X/CAV1 6 GO:0034976 response to endoplasmic reticulum stress 11/435 256/18722 0.0375470693145628 0.320990535492545 P4HB/HSP90B1/BCAP31/ERP29/PARK7/CALR/PDIA3/CCND1/CAV1/ERLEC1/LPCAT3 11 GO:0010644 cell communication by electrical coupling 3/435 32/18722 0.037558407362408 0.320990535492545 GJA1/GJA5/CAV1 3 GO:0014044 Schwann cell development 3/435 32/18722 0.037558407362408 0.320990535492545 SOD1/ITGB4/DAG1 3 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 3/435 32/18722 0.037558407362408 0.320990535492545 CDKN1C/HSP90AB1/FERMT1 3 GO:0051497 negative regulation of stress fiber assembly 3/435 32/18722 0.037558407362408 0.320990535492545 MET/TACSTD2/WASF2 3 GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 3/435 32/18722 0.037558407362408 0.320990535492545 CDKN1C/HSP90AB1/FERMT1 3 GO:0034284 response to monosaccharide 10/435 225/18722 0.0380061135207984 0.323210788445194 SERPINF1/KRT18/GSTP1/GJA1/MPC2/HMGN3/BAD/FIS1/PHPT1/TXN2 10 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 14/435 355/18722 0.0386971305860654 0.323210788445194 PEG10/CDKN1C/FBN2/FOLR1/BMP7/LRP2/PARP1/FBN1/HSP90AB1/FERMT1/EID2/NREP/CAV1/ITGB5 14 GO:0007229 integrin-mediated signaling pathway 6/435 107/18722 0.0386974238081939 0.323210788445194 ITGA6/ITGB4/FERMT1/LAMA5/ITGB5/CD47 6 GO:0001755 neural crest cell migration 4/435 55/18722 0.0387201952813976 0.323210788445194 NRP2/FOLR1/BMP7/LAMA5 4 GO:0098900 regulation of action potential 4/435 55/18722 0.0387201952813976 0.323210788445194 DSP/GJA5/DSC2/CAV1 4 GO:1901605 alpha-amino acid metabolic process 9/435 195/18722 0.0389377355489668 0.323210788445194 COMT/GCSH/SMS/GLDC/CLN3/ADI1/PARK7/CDO1/ASS1 9 GO:0071241 cellular response to inorganic substance 10/435 226/18722 0.0389807473494298 0.323210788445194 SERPINF1/SOD1/EGFR/CDH1/HSD17B1/PARP1/APP/CALR/BAD/BNIP3 10 GO:0001763 morphogenesis of a branching structure 9/435 196/18722 0.0400137725795577 0.323210788445194 SPINT2/SPINT1/MAGED1/BMP7/TGM2/MET/DAG1/LAMA5/TACSTD2 9 GO:0033138 positive regulation of peptidyl-serine phosphorylation 6/435 108/18722 0.0402064144842353 0.323210788445194 EGFR/APP/HSP90AB1/PARK7/MIF/CAV1 6 GO:0014032 neural crest cell development 5/435 81/18722 0.0402991514496161 0.323210788445194 NRP2/FOLR1/BMP7/LAMA5/PDCD6 5 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 5/435 81/18722 0.0402991514496161 0.323210788445194 PEG10/FBN2/FBN1/EID2/CAV1 5 GO:0010984 regulation of lipoprotein particle clearance 3/435 33/18722 0.0406240207271232 0.323210788445194 ANXA2/LRPAP1/CNPY2 3 GO:0033198 response to ATP 3/435 33/18722 0.0406240207271232 0.323210788445194 SOD1/HSPD1/HSP90B1 3 GO:0042558 pteridine-containing compound metabolic process 3/435 33/18722 0.0406240207271232 0.323210788445194 FOLR1/GGH/SLC19A1 3 GO:1900181 negative regulation of protein localization to nucleus 3/435 33/18722 0.0406240207271232 0.323210788445194 MAGED1/FERMT1/TRIM29 3 GO:1903715 regulation of aerobic respiration 3/435 33/18722 0.0406240207271232 0.323210788445194 COX7A2/PARK7/BNIP3 3 GO:1904031 positive regulation of cyclin-dependent protein kinase activity 3/435 33/18722 0.0406240207271232 0.323210788445194 EGFR/HSP90AB1/CCND1 3 GO:0001921 positive regulation of receptor recycling 2/435 14/18722 0.040758701904006 0.323210788445194 ANXA2/NSG1 2 GO:0003188 heart valve formation 2/435 14/18722 0.040758701904006 0.323210788445194 GJA5/EFNA1 2 GO:0010421 hydrogen peroxide-mediated programmed cell death 2/435 14/18722 0.040758701904006 0.323210788445194 MET/PARK7 2 GO:0010771 negative regulation of cell morphogenesis involved in differentiation 2/435 14/18722 0.040758701904006 0.323210788445194 FBLN1/TACSTD2 2 GO:0019321 pentose metabolic process 2/435 14/18722 0.040758701904006 0.323210788445194 DCXR/RPIA 2 GO:0035437 maintenance of protein localization in endoplasmic reticulum 2/435 14/18722 0.040758701904006 0.323210788445194 GJA1/KDELR1 2 GO:0035672 oligopeptide transmembrane transport 2/435 14/18722 0.040758701904006 0.323210788445194 GJA1/SLC13A3 2 GO:0036151 phosphatidylcholine acyl-chain remodeling 2/435 14/18722 0.040758701904006 0.323210788445194 DBI/LPCAT3 2 GO:0042415 norepinephrine metabolic process 2/435 14/18722 0.040758701904006 0.323210788445194 AKR1B1/LY6E 2 GO:0042921 glucocorticoid receptor signaling pathway 2/435 14/18722 0.040758701904006 0.323210788445194 CALR/PHB 2 GO:0044764 multi-organism cellular process 2/435 14/18722 0.040758701904006 0.323210788445194 CTSL/CAV1 2 GO:0046655 folic acid metabolic process 2/435 14/18722 0.040758701904006 0.323210788445194 FOLR1/SLC19A1 2 GO:0047484 regulation of response to osmotic stress 2/435 14/18722 0.040758701904006 0.323210788445194 CLN3/BAD 2 GO:0071285 cellular response to lithium ion 2/435 14/18722 0.040758701904006 0.323210788445194 CDH1/CALR 2 GO:0072350 tricarboxylic acid metabolic process 2/435 14/18722 0.040758701904006 0.323210788445194 IDH1/ASS1 2 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading 2/435 14/18722 0.040758701904006 0.323210788445194 FBLN1/TACSTD2 2 GO:1901857 positive regulation of cellular respiration 2/435 14/18722 0.040758701904006 0.323210788445194 IL10RB/PARK7 2 GO:1904152 regulation of retrograde protein transport, ER to cytosol 2/435 14/18722 0.040758701904006 0.323210788445194 BCAP31/ERLEC1 2 GO:1904294 positive regulation of ERAD pathway 2/435 14/18722 0.040758701904006 0.323210788445194 BCAP31/CAV1 2 GO:0050671 positive regulation of lymphocyte proliferation 7/435 137/18722 0.0410225464884176 0.324624414665614 CD24/PNP/RPS3/SLC39A10/CD46/MIF/CD55 7 GO:0071248 cellular response to metal ion 9/435 197/18722 0.0411098023599367 0.324624414665614 SERPINF1/SOD1/EGFR/CDH1/HSD17B1/PARP1/APP/CALR/BNIP3 9 GO:0060562 epithelial tube morphogenesis 13/435 325/18722 0.041183082173904 0.324624414665614 SPINT2/SPINT1/LMO4/MAGED1/FOLR1/BMP7/RPS7/LRP2/MET/LGR5/DAG1/LAMA5/TACSTD2 13 GO:0001822 kidney development 12/435 293/18722 0.0418662651402853 0.329353501312344 SERPINF1/CD24/MAGED1/BMP7/LRP2/MME/FBN1/AKR1B1/ADAMTS6/ASS1/LAMA5/TACSTD2 12 GO:1905897 regulation of response to endoplasmic reticulum stress 5/435 82/18722 0.0421321519879194 0.330787550428962 BCAP31/ERP29/PARK7/CAV1/LPCAT3 5 GO:0032946 positive regulation of mononuclear cell proliferation 7/435 138/18722 0.0423912668282426 0.332162857107636 CD24/PNP/RPS3/SLC39A10/CD46/MIF/CD55 7 GO:0002011 morphogenesis of an epithelial sheet 4/435 57/18722 0.0432776302792104 0.337551908208217 BMP7/DAG1/FERMT1/RHOC 4 GO:0002698 negative regulation of immune effector process 6/435 110/18722 0.0433349429794729 0.337551908208217 RPS19/CD59/LGALS3/CD46/CD55/CD47 6 GO:0009408 response to heat 6/435 110/18722 0.0433349429794729 0.337551908208217 SOD1/HSPD1/HSP90AB1/RBBP7/PDCD6/HSBP1L1 6 GO:0070997 neuron death 14/435 361/18722 0.0434778141082116 0.337941542046561 SERPINF1/SOD1/ARL6IP5/PARP1/HSPD1/APP/NENF/CLN3/HSP90AB1/PARK7/BAD/FIS1/PSMC1/BNIP3 14 GO:0034470 ncRNA processing 15/435 395/18722 0.0437180694760708 0.337941542046561 RPS21/RPS14/RPS27/RPS28/RPS16/RPS7/RPL10A/RPS19/RPS25/RPS17/RPL7A/NHP2/GTF2H5/LIN28B/TRMT112 15 GO:0000038 very long-chain fatty acid metabolic process 3/435 34/18722 0.0438119815693419 0.337941542046561 SLC27A2/HACD3/TECR 3 GO:0032743 positive regulation of interleukin-2 production 3/435 34/18722 0.0438119815693419 0.337941542046561 PNP/RPS3/STOML2 3 GO:0098751 bone cell development 3/435 34/18722 0.0438119815693419 0.337941542046561 ANXA2/FBN1/WASF2 3 GO:0051899 membrane depolarization 5/435 83/18722 0.044014699214593 0.338844678583939 IFI6/PARP1/GJA5/PARK7/CAV1 5 GO:0043666 regulation of phosphoprotein phosphatase activity 4/435 58/18722 0.045664640755051 0.349128445893102 HSP90B1/HSP90AB1/SLC39A10/LGALS3 4 GO:0002679 respiratory burst involved in defense response 2/435 15/18722 0.0463210599175837 0.349128445893102 RPS19/PRDX2 2 GO:0006268 DNA unwinding involved in DNA replication 2/435 15/18722 0.0463210599175837 0.349128445893102 HMGA1/SSBP1 2 GO:0010940 positive regulation of necrotic cell death 2/435 15/18722 0.0463210599175837 0.349128445893102 HEBP2/BNIP3 2 GO:0019511 peptidyl-proline hydroxylation 2/435 15/18722 0.0463210599175837 0.349128445893102 P4HB/PRDX4 2 GO:0031958 corticosteroid receptor signaling pathway 2/435 15/18722 0.0463210599175837 0.349128445893102 CALR/PHB 2 GO:0048569 post-embryonic animal organ development 2/435 15/18722 0.0463210599175837 0.349128445893102 EFEMP1/FBN1 2 GO:0070207 protein homotrimerization 2/435 15/18722 0.0463210599175837 0.349128445893102 MIF/SLC1A5 2 GO:0071474 cellular hyperosmotic response 2/435 15/18722 0.0463210599175837 0.349128445893102 SLC2A1/AKR1B1 2 GO:0097468 programmed cell death in response to reactive oxygen species 2/435 15/18722 0.0463210599175837 0.349128445893102 MET/PARK7 2 GO:1905146 lysosomal protein catabolic process 2/435 15/18722 0.0463210599175837 0.349128445893102 LRP2/CLN3 2 GO:0001893 maternal placenta development 3/435 35/18722 0.0471208897701401 0.349826192908901 BSG/GJA1/NR2F2 3 GO:0006739 NADP metabolic process 3/435 35/18722 0.0471208897701401 0.349826192908901 DCXR/IDH1/RPIA 3 GO:0032232 negative regulation of actin filament bundle assembly 3/435 35/18722 0.0471208897701401 0.349826192908901 MET/TACSTD2/WASF2 3 GO:0046471 phosphatidylglycerol metabolic process 3/435 35/18722 0.0471208897701401 0.349826192908901 STOML2/DNAJC19/HADHA 3 GO:0086005 ventricular cardiac muscle cell action potential 3/435 35/18722 0.0471208897701401 0.349826192908901 DSP/DSC2/CAV1 3 GO:0090181 regulation of cholesterol metabolic process 3/435 35/18722 0.0471208897701401 0.349826192908901 SOD1/ACADVL/LPCAT3 3 GO:0097421 liver regeneration 3/435 35/18722 0.0471208897701401 0.349826192908901 EGFR/RPS16/CCND1 3 GO:0098801 regulation of renal system process 3/435 35/18722 0.0471208897701401 0.349826192908901 COMT/GJA1/GJA5 3 GO:0030433 ubiquitin-dependent ERAD pathway 5/435 85/18722 0.0479289769694385 0.35515910462185 HSP90B1/BCAP31/CALR/CAV1/ERLEC1 5 GO:0062012 regulation of small molecule metabolic process 13/435 334/18722 0.0492584294159561 0.364328234016707 PHLDA2/SOD1/COMT/PARP1/APP/CLN3/PARK7/BAD/ACADVL/DDB1/CAV1/LCMT1/LPCAT3 13 GO:0042886 amide transport 12/435 301/18722 0.049522895527741 0.364719078869453 FAM3B/EGFR/FOLR1/LRP2/GJA1/SLC13A3/PARK7/MPC2/HMGN3/BAD/SLC19A1/PHPT1 12 GO:0071692 protein localization to extracellular region 14/435 368/18722 0.0495651079360401 0.364719078869453 FAM3B/EGFR/FBN2/WLS/GJA1/FBN1/MYH10/ERP29/PARK7/MPC2/HMGN3/BAD/KCNN4/PHPT1 14 GO:0038061 NIK/NF-kappaB signaling 7/435 143/18722 0.0496767571141114 0.364719078869453 EGFR/PRDX1/BMP7/APP/RPS3/CALR/PHB 7 GO:0014031 mesenchymal cell development 5/435 86/18722 0.0499609077013486 0.364719078869453 NRP2/FOLR1/BMP7/LAMA5/PDCD6 5 GO:0048864 stem cell development 5/435 86/18722 0.0499609077013486 0.364719078869453 NRP2/FOLR1/BMP7/LAMA5/PDCD6 5 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 3/435 36/18722 0.0505492075801149 0.364719078869453 MPC2/BAD/PHPT1 3 GO:0044743 protein transmembrane import into intracellular organelle 3/435 36/18722 0.0505492075801149 0.364719078869453 HSPD1/ROMO1/DNAJC19 3 GO:0051385 response to mineralocorticoid 3/435 36/18722 0.0505492075801149 0.364719078869453 PARP1/ATP2B1/CCND1 3 GO:0060348 bone development 9/435 205/18722 0.0506124159385068 0.364719078869453 ANXA2/PPIB/TGM2/HSD17B1/GNAS/GJA1/FBN1/MSX2/WASF2 9 GO:0006081 cellular aldehyde metabolic process 4/435 60/18722 0.0506547096687961 0.364719078869453 ALDH7A1/IDH1/ADH5/PARK7 4 GO:0031638 zymogen activation 4/435 60/18722 0.0506547096687961 0.364719078869453 PERP/CTSL/BAD/ASPH 4 GO:0010821 regulation of mitochondrion organization 7/435 144/18722 0.051223200843829 0.364719078869453 PISD/PDCD5/PARK7/BAD/LMNA/FIS1/BNIP3 7 GO:0017038 protein import 9/435 206/18722 0.0518937010715482 0.364719078869453 CDH1/RPL23/HSPD1/HSP90AB1/ROMO1/PDCD5/LMNA/FERMT1/DNAJC19 9 GO:0007029 endoplasmic reticulum organization 5/435 87/18722 0.0520427859816791 0.364719078869453 WDR83OS/LMAN1/REEP5/LPCAT3/EMC7 5 GO:0150104 transport across blood-brain barrier 5/435 87/18722 0.0520427859816791 0.364719078869453 SLC2A1/LRP2/SLC13A3/SLC19A1/SLC1A5 5 GO:2000177 regulation of neural precursor cell proliferation 5/435 87/18722 0.0520427859816791 0.364719078869453 SPINT2/SPINT1/ADGRG1/LRP2/SLC6A4 5 GO:0001732 formation of cytoplasmic translation initiation complex 2/435 16/18722 0.0521427842343091 0.364719078869453 EIF3G/EIF2S2 2 GO:0001977 renal system process involved in regulation of blood volume 2/435 16/18722 0.0521427842343091 0.364719078869453 GJA1/GJA5 2 GO:0002713 negative regulation of B cell mediated immunity 2/435 16/18722 0.0521427842343091 0.364719078869453 CD46/CD55 2 GO:0002890 negative regulation of immunoglobulin mediated immune response 2/435 16/18722 0.0521427842343091 0.364719078869453 CD46/CD55 2 GO:0006544 glycine metabolic process 2/435 16/18722 0.0521427842343091 0.364719078869453 GCSH/GLDC 2 GO:0006555 methionine metabolic process 2/435 16/18722 0.0521427842343091 0.364719078869453 SMS/ADI1 2 GO:0006857 oligopeptide transport 2/435 16/18722 0.0521427842343091 0.364719078869453 GJA1/SLC13A3 2 GO:0009415 response to water 2/435 16/18722 0.0521427842343091 0.364719078869453 KRT8/AKR1B1 2 GO:0034138 toll-like receptor 3 signaling pathway 2/435 16/18722 0.0521427842343091 0.364719078869453 COLEC12/CAV1 2 GO:0045838 positive regulation of membrane potential 2/435 16/18722 0.0521427842343091 0.364719078869453 BAD/STOML2 2 GO:0050862 positive regulation of T cell receptor signaling pathway 2/435 16/18722 0.0521427842343091 0.364719078869453 RPS3/KCNN4 2 GO:0097284 hepatocyte apoptotic process 2/435 16/18722 0.0521427842343091 0.364719078869453 KRT18/KRT8 2 GO:1905906 regulation of amyloid fibril formation 2/435 16/18722 0.0521427842343091 0.364719078869453 APP/PFDN1 2 GO:0050954 sensory perception of mechanical stimulus 8/435 175/18722 0.0521685616982842 0.364719078869453 SOD1/NDUFB9/LRP2/ALDH7A1/TIMM13/TIMM8B/ATP6V1B1/TBL1X 8 GO:1905475 regulation of protein localization to membrane 8/435 175/18722 0.0521685616982842 0.364719078869453 EGFR/VAMP8/CLN3/PDCD5/LGALS3/DAG1/FIS1/TMEM59 8 GO:0090287 regulation of cellular response to growth factor stimulus 12/435 304/18722 0.0526260894694483 0.367268846614827 PEG10/CDKN1C/FBN2/FOLR1/LRP2/FBN1/HSP90AB1/FERMT1/EID2/NREP/CAV1/PDCD6 12 GO:0001655 urogenital system development 13/435 338/18722 0.0531761720582574 0.369718313672878 SERPINF1/CD24/MAGED1/BMP7/LRP2/MME/FBN1/LGR5/AKR1B1/ADAMTS6/ASS1/LAMA5/TACSTD2 13 GO:0040014 regulation of multicellular organism growth 4/435 61/18722 0.0532573764957141 0.369718313672878 SOD1/PPIB/APP/ADRB1 4 GO:0090342 regulation of cell aging 4/435 61/18722 0.0532573764957141 0.369718313672878 HMGA1/YPEL3/LMNA/MIF 4 GO:0021782 glial cell development 6/435 116/18722 0.0536166253639762 0.371560396786784 GSTP1/SOD1/EGFR/APP/ITGB4/DAG1 6 GO:0003161 cardiac conduction system development 3/435 37/18722 0.0540952698710375 0.372918088640585 GJA1/GJA5/MSX2 3 GO:0006862 nucleotide transport 3/435 37/18722 0.0540952698710375 0.372918088640585 GJA1/SLC19A1/CD47 3 GO:0032570 response to progesterone 3/435 37/18722 0.0540952698710375 0.372918088640585 CLDN4/BAD/CAV1 3 GO:0007043 cell-cell junction assembly 7/435 146/18722 0.0544063709769132 0.373760433950773 CLDN4/GJA1/GJA5/CLDN7/CAV1/RHOC/LSR 7 GO:0042542 response to hydrogen peroxide 7/435 146/18722 0.0544063709769132 0.373760433950773 SOD1/MET/HSPD1/RPS3/PARK7/BAD/BNIP3 7 GO:0046942 carboxylic acid transport 11/435 273/18722 0.0549152490864226 0.376275998125885 FOLR1/LRP2/ARL6IP5/GJA1/CLN3/SLC13A3/SLC43A2/MPC2/SLC38A9/SLC19A1/SLC1A5 11 GO:0043405 regulation of MAP kinase activity 8/435 177/18722 0.0550578223186473 0.376275998125885 CD24/GSTP1/MAGED1/EGFR/BMP7/RPS3/ERP29/CAV1 8 GO:0098739 import across plasma membrane 8/435 177/18722 0.0550578223186473 0.376275998125885 SLC2A1/FOLR1/LRP2/ARL6IP5/SLC39A10/SLC43A2/SLC19A1/SLC1A5 8 GO:0045428 regulation of nitric oxide biosynthetic process 4/435 62/18722 0.0559314428146808 0.380276149858577 HSP90AB1/ASS1/CAV1/CD47 4 GO:0046847 filopodium assembly 4/435 62/18722 0.0559314428146808 0.380276149858577 CLN3/ITGB4/S1PR2/RAB17 4 GO:0060135 maternal process involved in female pregnancy 4/435 62/18722 0.0559314428146808 0.380276149858577 BSG/GJA1/NR2F2/AKR1B1 4 GO:0001889 liver development 7/435 147/18722 0.0560432889166306 0.380383008993323 KRT18/EGFR/RPS16/MET/ASS1/CCND1/LSR 7 GO:1903320 regulation of protein modification by small protein conjugation or removal 10/435 242/18722 0.0569713147531203 0.380714941068658 RPL37/RPL23/RPS7/HSP90AB1/RPS3/PARK7/NPM1/SKP2/CAV1/PDCD6 10 GO:0006413 translational initiation 6/435 118/18722 0.0573457547125118 0.380714941068658 RPS5/RPS17/RPS3/EIF3G/EIF2S2/NPM1 6 GO:0044272 sulfur compound biosynthetic process 7/435 148/18722 0.0577105405334234 0.380714941068658 GSTP1/ACSS1/ADI1/TECR/CDO1/MPC2/CHPF 7 GO:0032373 positive regulation of sterol transport 3/435 38/18722 0.0577572939160847 0.380714941068658 ANXA2/CAV1/LPCAT3 3 GO:0032376 positive regulation of cholesterol transport 3/435 38/18722 0.0577572939160847 0.380714941068658 ANXA2/CAV1/LPCAT3 3 GO:0032941 secretion by tissue 3/435 38/18722 0.0577572939160847 0.380714941068658 EGFR/VAMP8/KCNN4 3 GO:0097242 amyloid-beta clearance 3/435 38/18722 0.0577572939160847 0.380714941068658 LRPAP1/LRP2/MME 3 GO:1901031 regulation of response to reactive oxygen species 3/435 38/18722 0.0577572939160847 0.380714941068658 BMP7/MET/PARK7 3 GO:1903725 regulation of phospholipid metabolic process 3/435 38/18722 0.0577572939160847 0.380714941068658 IDH1/STOML2/DNAJC19 3 GO:0000097 sulfur amino acid biosynthetic process 2/435 17/18722 0.058208880299858 0.380714941068658 ADI1/CDO1 2 GO:0006901 vesicle coating 2/435 17/18722 0.058208880299858 0.380714941068658 TMED9/PDCD6 2 GO:0009084 glutamine family amino acid biosynthetic process 2/435 17/18722 0.058208880299858 0.380714941068658 CLN3/ASS1 2 GO:0015867 ATP transport 2/435 17/18722 0.058208880299858 0.380714941068658 GJA1/CD47 2 GO:0036035 osteoclast development 2/435 17/18722 0.058208880299858 0.380714941068658 ANXA2/FBN1 2 GO:0042053 regulation of dopamine metabolic process 2/435 17/18722 0.058208880299858 0.380714941068658 COMT/PARK7 2 GO:0042069 regulation of catecholamine metabolic process 2/435 17/18722 0.058208880299858 0.380714941068658 COMT/PARK7 2 GO:0044539 long-chain fatty acid import into cell 2/435 17/18722 0.058208880299858 0.380714941068658 SLC2A1/SLC27A2 2 GO:0070206 protein trimerization 2/435 17/18722 0.058208880299858 0.380714941068658 MIF/SLC1A5 2 GO:0070293 renal absorption 2/435 17/18722 0.058208880299858 0.380714941068658 CLDN4/MAGED2 2 GO:0090136 epithelial cell-cell adhesion 2/435 17/18722 0.058208880299858 0.380714941068658 DSP/ITGB5 2 GO:0090399 replicative senescence 2/435 17/18722 0.058208880299858 0.380714941068658 MME/ROMO1 2 GO:0140354 lipid import into cell 2/435 17/18722 0.058208880299858 0.380714941068658 SLC2A1/SLC27A2 2 GO:1903829 positive regulation of cellular protein localization 11/435 276/18722 0.0584574494977369 0.381709781621361 EGFR/CDH1/PARP1/CLN3/HSP90AB1/PDCD5/PARK7/LGALS3/FIS1/LAMTOR5/NPM1 11 GO:1904589 regulation of protein import 4/435 63/18722 0.0586765737078843 0.382509394006752 CDH1/HSP90AB1/PDCD5/FERMT1 4 GO:0022407 regulation of cell-cell adhesion 16/435 448/18722 0.0598737055604416 0.389671468589914 SPINT2/CD24/CDH1/BMP7/PRDX2/HSPD1/PNP/RPS3/LGALS3/TENM3/BAD/ASS1/CD46/CD55/CAV1/CD47 16 GO:0006469 negative regulation of protein kinase activity 9/435 212/18722 0.0600274032955733 0.390030270674193 GSTP1/CDKN1C/PKIB/MLLT1/BMP7/NR2F2/PARK7/NPM1/CAV1 9 GO:0051346 negative regulation of hydrolase activity 14/435 379/18722 0.0602867080767868 0.390830849360169 SERPINF1/IFI6/SPINT2/SPINT1/ITIH5/PRDX5/PEBP1/ANXA2/APP/PARK7/LGALS3/APLP2/LAMTOR5/AMOT 14 GO:0043434 response to peptide hormone 15/435 414/18722 0.0607203648320298 0.390830849360169 GSTP1/BSG/SLC2A1/BMP7/PARP1/GJA1/FBN1/GGH/CDO1/DAG1/ASS1/ATP2B1/HADHA/CAV1/CYC1 15 GO:0014033 neural crest cell differentiation 5/435 91/18722 0.0608699569060535 0.390830849360169 NRP2/FOLR1/BMP7/LAMA5/PDCD6 5 GO:0061008 hepaticobiliary system development 7/435 150/18722 0.0611363225723254 0.390830849360169 KRT18/EGFR/RPS16/MET/ASS1/CCND1/LSR 7 GO:0070665 positive regulation of leukocyte proliferation 7/435 150/18722 0.0611363225723254 0.390830849360169 CD24/PNP/RPS3/SLC39A10/CD46/MIF/CD55 7 GO:0071901 negative regulation of protein serine/threonine kinase activity 6/435 120/18722 0.0612268162742332 0.390830849360169 GSTP1/CDKN1C/PKIB/BMP7/NR2F2/CAV1 6 GO:0016126 sterol biosynthetic process 4/435 64/18722 0.061492381533458 0.390830849360169 SOD1/CYB5R1/FDFT1/LPCAT3 4 GO:0032507 maintenance of protein location in cell 4/435 64/18722 0.061492381533458 0.390830849360169 GJA1/PARK7/KDELR1/CAV1 4 GO:0045995 regulation of embryonic development 4/435 64/18722 0.061492381533458 0.390830849360169 PHLDA2/DAG1/AMOT/LAMA5 4 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 4/435 64/18722 0.061492381533458 0.390830849360169 MPC2/HMGN3/BAD/PHPT1 4 GO:0080164 regulation of nitric oxide metabolic process 4/435 64/18722 0.061492381533458 0.390830849360169 HSP90AB1/ASS1/CAV1/CD47 4 GO:1903409 reactive oxygen species biosynthetic process 4/435 64/18722 0.061492381533458 0.390830849360169 PAGE4/SOD1/HSPD1/PARK7 4 GO:0071548 response to dexamethasone 3/435 39/18722 0.0615333887165493 0.390830849360169 SERPINF1/EGFR/ASS1 3 GO:0086091 regulation of heart rate by cardiac conduction 3/435 39/18722 0.0615333887165493 0.390830849360169 DSP/DSC2/CAV1 3 GO:0031098 stress-activated protein kinase signaling cascade 10/435 247/18722 0.0635529052102069 0.401855293335932 PAGE4/GSTP1/EGFR/PRDX1/DUSP9/ARL6IP5/APP/HACD3/AKR1B1/PRMT1 10 GO:1902475 L-alpha-amino acid transmembrane transport 4/435 65/18722 0.0643784275763375 0.401855293335932 ARL6IP5/SLC43A2/SLC38A9/SLC1A5 4 GO:1905330 regulation of morphogenesis of an epithelium 4/435 65/18722 0.0643784275763375 0.401855293335932 MAGED1/BMP7/GJA1/TACSTD2 4 GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 2/435 18/18722 0.0645049075127192 0.401855293335932 CD46/CD55 2 GO:0006085 acetyl-CoA biosynthetic process 2/435 18/18722 0.0645049075127192 0.401855293335932 ACSS1/MPC2 2 GO:0043217 myelin maintenance 2/435 18/18722 0.0645049075127192 0.401855293335932 SOD1/DEGS1 2 GO:0048268 clathrin coat assembly 2/435 18/18722 0.0645049075127192 0.401855293335932 CLTA/NSG1 2 GO:0060973 cell migration involved in heart development 2/435 18/18722 0.0645049075127192 0.401855293335932 FOLR1/BMP7 2 GO:0071318 cellular response to ATP 2/435 18/18722 0.0645049075127192 0.401855293335932 SOD1/HSP90B1 2 GO:0071360 cellular response to exogenous dsRNA 2/435 18/18722 0.0645049075127192 0.401855293335932 COLEC12/CAV1 2 GO:1903209 positive regulation of oxidative stress-induced cell death 2/435 18/18722 0.0645049075127192 0.401855293335932 SOD1/PARK7 2 GO:0006644 phospholipid metabolic process 14/435 383/18722 0.0645469121062566 0.401855293335932 ISYNA1/TMEM150A/CLN3/IDH1/SERINC2/PRDX6/PISD/DBI/PYURF/STOML2/DNAJC19/HADHA/FDFT1/LPCAT3 14 GO:0021915 neural tube development 7/435 152/18722 0.0646841766285462 0.401855293335932 SPINT2/SPINT1/LMO4/FOLR1/BMP7/RPS7/LRP2 7 GO:0007249 I-kappaB kinase/NF-kappaB signaling 11/435 281/18722 0.0646908824500856 0.401855293335932 GSTP1/TGM2/PRDX4/WLS/TMED4/GJA1/S100A13/HACD3/SHISA5/LAMTOR5/RHOC 11 GO:0033002 muscle cell proliferation 10/435 248/18722 0.0649256255372311 0.402681348355523 GSTP1/EGFR/COMT/TGM2/DNMT1/GJA1/AKR1B1/PHB/SKP2/S1PR2 10 GO:0009069 serine family amino acid metabolic process 3/435 40/18722 0.0654215638923166 0.403229171840961 GCSH/GLDC/CDO1 3 GO:0014037 Schwann cell differentiation 3/435 40/18722 0.0654215638923166 0.403229171840961 SOD1/ITGB4/DAG1 3 GO:0045740 positive regulation of DNA replication 3/435 40/18722 0.0654215638923166 0.403229171840961 EGFR/SSBP1/STOML2 3 GO:0045777 positive regulation of blood pressure 3/435 40/18722 0.0654215638923166 0.403229171840961 ADRB1/ADH5/NR2F2 3 GO:1901796 regulation of signal transduction by p53 class mediator 5/435 93/18722 0.065582703558325 0.403593713810719 RPL37/RPL23/RPS7/MIF/NPM1 5 GO:0050870 positive regulation of T cell activation 9/435 216/18722 0.0658799751916484 0.404793574275392 CD24/HSPD1/PNP/RPS3/BAD/CD46/CD55/CAV1/CD47 9 GO:0014015 positive regulation of gliogenesis 4/435 66/18722 0.0673342237114378 0.412835313566105 SPINT1/EGFR/LRP2/DAG1 4 GO:0007596 blood coagulation 9/435 217/18722 0.0673974254646711 0.412835313566105 ANXA2/F5/FBLN1/PRDX2/CD59/GNAS/ANXA5/LMAN1/CAV1 9 GO:0051702 biological process involved in interaction with symbiont 5/435 94/18722 0.0680135229782988 0.415323318557297 PPIB/HSPD1/ROMO1/PHB/DDB1 5 GO:0061326 renal tubule development 5/435 94/18722 0.0680135229782988 0.415323318557297 CD24/MAGED1/LGR5/LAMA5/TACSTD2 5 GO:0006520 cellular amino acid metabolic process 11/435 284/18722 0.0686311114508424 0.418448856719543 COMT/GCSH/ECHS1/SMS/GLDC/CLN3/ADI1/PARK7/CDO1/ASS1/IARS2 11 GO:0008217 regulation of blood pressure 8/435 186/18722 0.0693082630935653 0.421279258158584 SOD1/MME/GJA1/ADRB1/GJA5/ADH5/NR2F2/ATP2B1 8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 8/435 186/18722 0.0693082630935653 0.421279258158584 TGM2/WLS/TMED4/GJA1/S100A13/SHISA5/LAMTOR5/RHOC 8 GO:0061077 chaperone-mediated protein folding 4/435 67/18722 0.0703592340754427 0.424853746135261 PPIB/HSPE1/PDCD5/FKBP2 4 GO:0050764 regulation of phagocytosis 5/435 95/18722 0.0704937730615906 0.424853746135261 SOD1/TGM2/CALR/SNX3/CD47 5 GO:0009746 response to hexose 9/435 219/18722 0.070497805948847 0.424853746135261 SERPINF1/KRT18/GJA1/MPC2/HMGN3/BAD/FIS1/PHPT1/TXN2 9 GO:0007039 protein catabolic process in the vacuole 2/435 19/18722 0.0710169616744945 0.424853746135261 LRP2/CLN3 2 GO:0015802 basic amino acid transport 2/435 19/18722 0.0710169616744945 0.424853746135261 CLN3/SLC38A9 2 GO:0044827 modulation by host of viral genome replication 2/435 19/18722 0.0710169616744945 0.424853746135261 PPIB/PHB 2 GO:0046794 transport of virus 2/435 19/18722 0.0710169616744945 0.424853746135261 CTSL/CAV1 2 GO:0086014 atrial cardiac muscle cell action potential 2/435 19/18722 0.0710169616744945 0.424853746135261 GJA1/GJA5 2 GO:0086026 atrial cardiac muscle cell to AV node cell signaling 2/435 19/18722 0.0710169616744945 0.424853746135261 GJA1/GJA5 2 GO:0086066 atrial cardiac muscle cell to AV node cell communication 2/435 19/18722 0.0710169616744945 0.424853746135261 GJA1/GJA5 2 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 12/435 320/18722 0.0713994797017813 0.424853746135261 LSM7/MBNL3/PRDX6/SNRPG/SNRPF/C1QBP/SNRPD2/SNRPE/SF3B6/SNRPB2/NPM1/SNRPD3 12 GO:0000398 mRNA splicing, via spliceosome 12/435 320/18722 0.0713994797017813 0.424853746135261 LSM7/MBNL3/PRDX6/SNRPG/SNRPF/C1QBP/SNRPD2/SNRPE/SF3B6/SNRPB2/NPM1/SNRPD3 12 GO:0009895 negative regulation of catabolic process 12/435 320/18722 0.0713994797017813 0.424853746135261 ANXA2/EGFR/RPL23/RPS7/SLIRP/MET/HSP90AB1/EFNA1/PARK7/ATRAID/PHB/SNX3 12 GO:0071496 cellular response to external stimulus 12/435 320/18722 0.0713994797017813 0.424853746135261 GSTP1/EGFR/SLC2A1/COMT/FOLR1/GJA1/DAG1/BAD/ATP2B1/SKP2/BNIP3/TXN2 12 GO:1904375 regulation of protein localization to cell periphery 6/435 125/18722 0.0715950125900484 0.425377574803035 EGFR/VAMP8/CLN3/LGALS3/DAG1/TMEM59 6 GO:0003073 regulation of systemic arterial blood pressure 5/435 96/18722 0.073023272377978 0.432305174325935 MME/GJA1/ADRB1/GJA5/NR2F2 5 GO:1901607 alpha-amino acid biosynthetic process 4/435 68/18722 0.0734528767437396 0.432305174325935 CLN3/ADI1/PARK7/ASS1 4 GO:0000413 protein peptidyl-prolyl isomerization 3/435 42/18722 0.073525747364507 0.432305174325935 PPIB/FKBP3/FKBP2 3 GO:0010939 regulation of necrotic cell death 3/435 42/18722 0.073525747364507 0.432305174325935 HEBP2/BNIP3/CAV1 3 GO:0046596 regulation of viral entry into host cell 3/435 42/18722 0.073525747364507 0.432305174325935 P4HB/LY6E/SNX3 3 GO:0046688 response to copper ion 3/435 42/18722 0.073525747364507 0.432305174325935 SOD1/APP/PARK7 3 GO:0072595 maintenance of protein localization in organelle 3/435 42/18722 0.073525747364507 0.432305174325935 GJA1/PARK7/KDELR1 3 GO:0002262 myeloid cell homeostasis 7/435 157/18722 0.0740895072998766 0.434973561402985 RPS14/SOD1/PRDX1/RPS19/RPS17/TMEM14C/PRMT1 7 GO:0007599 hemostasis 9/435 222/18722 0.0753125688824047 0.440845909863425 ANXA2/F5/FBLN1/PRDX2/CD59/GNAS/ANXA5/LMAN1/CAV1 9 GO:0050817 coagulation 9/435 222/18722 0.0753125688824047 0.440845909863425 ANXA2/F5/FBLN1/PRDX2/CD59/GNAS/ANXA5/LMAN1/CAV1 9 GO:0006721 terpenoid metabolic process 5/435 97/18722 0.0756018149236099 0.441233601257706 EGFR/LRP2/ADH5/AKR1B1/FDFT1 5 GO:0070252 actin-mediated cell contraction 5/435 97/18722 0.0756018149236099 0.441233601257706 DSP/GJA1/GJA5/DSC2/CAV1 5 GO:0051224 negative regulation of protein transport 6/435 127/18722 0.0760079717790425 0.442950728026025 ERP29/PARK7/LMAN1/FERMT1/SNX3/ERLEC1 6 GO:0015807 L-amino acid transport 4/435 69/18722 0.0766145254092494 0.443876915983763 ARL6IP5/SLC43A2/SLC38A9/SLC1A5 4 GO:0045665 negative regulation of neuron differentiation 4/435 69/18722 0.0766145254092494 0.443876915983763 BMP7/APP/SLC6A4/CALR 4 GO:0000375 RNA splicing, via transesterification reactions 12/435 324/18722 0.0766925787977499 0.443876915983763 LSM7/MBNL3/PRDX6/SNRPG/SNRPF/C1QBP/SNRPD2/SNRPE/SF3B6/SNRPB2/NPM1/SNRPD3 12 GO:0071900 regulation of protein serine/threonine kinase activity 13/435 359/18722 0.0772279143497084 0.443876915983763 CD24/GSTP1/MAGED1/EGFR/CDKN1C/PKIB/BMP7/HSP90AB1/RPS3/ERP29/NR2F2/CCND1/CAV1 13 GO:2000146 negative regulation of cell motility 13/435 359/18722 0.0772279143497084 0.443876915983763 SERPINF1/SPINT2/GSTP1/ADGRG1/CDH1/FBLN1/GJA1/NR2F2/DAG1/CALR/MIF/TACSTD2/S1PR2 13 GO:0006525 arginine metabolic process 2/435 20/18722 0.0777316579536922 0.443876915983763 CLN3/ASS1 2 GO:0030150 protein import into mitochondrial matrix 2/435 20/18722 0.0777316579536922 0.443876915983763 ROMO1/DNAJC19 2 GO:0032986 protein-DNA complex disassembly 2/435 20/18722 0.0777316579536922 0.443876915983763 RPL23/HMGA1 2 GO:0048025 negative regulation of mRNA splicing, via spliceosome 2/435 20/18722 0.0777316579536922 0.443876915983763 C1QBP/NPM1 2 GO:0051900 regulation of mitochondrial depolarization 2/435 20/18722 0.0777316579536922 0.443876915983763 IFI6/PARP1 2 GO:1903206 negative regulation of hydrogen peroxide-induced cell death 2/435 20/18722 0.0777316579536922 0.443876915983763 MET/PARK7 2 GO:1904292 regulation of ERAD pathway 2/435 20/18722 0.0777316579536922 0.443876915983763 BCAP31/CAV1 2 GO:2000678 negative regulation of transcription regulatory region DNA binding 2/435 20/18722 0.0777316579536922 0.443876915983763 MSX2/ZNF593 2 GO:1904591 positive regulation of protein import 3/435 43/18722 0.0777373522306666 0.443876915983763 CDH1/HSP90AB1/PDCD5 3 GO:1904029 regulation of cyclin-dependent protein kinase activity 5/435 98/18722 0.078229170580346 0.446041538885344 EGFR/CDKN1C/HSP90AB1/NR2F2/CCND1 5 GO:2001234 negative regulation of apoptotic signaling pathway 9/435 224/18722 0.0786321460350457 0.447694103396656 IFI6/ITGA6/GSTP1/PRDX2/NDUFA13/PARK7/LGALS3/LMNA/MIF 9 GO:0001819 positive regulation of cytokine production 16/435 467/18722 0.0797691756400174 0.452864602593327 SOD1/HSPD1/APP/PNP/RPS3/S100A13/PARK7/HILPDA/FERMT1/CD46/MIF/CADM1/CD55/PHB/STOML2/LAMTOR5 16 GO:0033674 positive regulation of kinase activity 16/435 467/18722 0.0797691756400174 0.452864602593327 LMO4/CD24/MAGED1/EGFR/RPLP1/MET/HSP90AB1/RPS3/EFNA1/ERP29/PARK7/DAG1/BAD/PHB/NPM1/CCND1 16 GO:0035637 multicellular organismal signaling 7/435 160/18722 0.0801001360977542 0.454092032290564 SOD1/DSP/GJA1/GJA5/DSC2/ATP2B1/CAV1 7 GO:0034101 erythrocyte homeostasis 6/435 129/18722 0.0805719534152436 0.456113332852817 RPS14/PRDX1/RPS19/RPS17/TMEM14C/PRMT1 6 GO:0042554 superoxide anion generation 3/435 44/18722 0.0820522455981903 0.461938075141862 GSTP1/SOD1/EGFR 3 GO:0060711 labyrinthine layer development 3/435 44/18722 0.0820522455981903 0.461938075141862 SPINT2/SPINT1/BMP7 3 GO:0089718 amino acid import across plasma membrane 3/435 44/18722 0.0820522455981903 0.461938075141862 ARL6IP5/SLC43A2/SLC1A5 3 GO:0051098 regulation of binding 13/435 363/18722 0.0824924030714442 0.461938075141862 PHLDA2/ANXA2/LRPAP1/MET/PARP1/APP/HSP90AB1/S100A10/PARK7/MSX2/ZNF593/LAMTOR5/CAV1 13 GO:0008380 RNA splicing 15/435 434/18722 0.0829677488953676 0.461938075141862 LSM7/MBNL3/PRDX6/SNRPG/SNRPF/C1QBP/LGALS3/SNRPD2/RPS26/SNRPE/SF3B6/SNRPB2/NPM1/SNRPD3/PRMT1 15 GO:0033555 multicellular organismal response to stress 4/435 71/18722 0.0831391236534864 0.461938075141862 VWA1/COMT/GJA1/ADRB1 4 GO:0050818 regulation of coagulation 4/435 71/18722 0.0831391236534864 0.461938075141862 ANXA2/PRDX2/ANXA5/CAV1 4 GO:0061515 myeloid cell development 4/435 71/18722 0.0831391236534864 0.461938075141862 ANXA2/APP/FBN1/WASF2 4 GO:0071230 cellular response to amino acid stimulus 4/435 71/18722 0.0831391236534864 0.461938075141862 DNMT1/ASS1/LAMTOR5/SLC38A9 4 GO:0051051 negative regulation of transport 16/435 470/18722 0.0832636660776918 0.461938075141862 LRPAP1/COMT/VAMP8/ARL6IP5/GJA1/ERP29/PARK7/LGALS3/SLC43A2/LMAN1/FERMT1/FIS1/SNX3/CAV1/ERLEC1/CD47 16 GO:0050863 regulation of T cell activation 12/435 329/18722 0.0836526355971461 0.461938075141862 CD24/SOD1/PRDX2/HSPD1/PNP/RPS3/LGALS3/BAD/CD46/CD55/CAV1/CD47 12 GO:0003091 renal water homeostasis 2/435 21/18722 0.0846361143487112 0.461938075141862 AKR1B1/ATP6V1B1 2 GO:0006067 ethanol metabolic process 2/435 21/18722 0.0846361143487112 0.461938075141862 ACSS1/ADH5 2 GO:0006450 regulation of translational fidelity 2/435 21/18722 0.0846361143487112 0.461938075141862 RPS5/IARS2 2 GO:0010988 regulation of low-density lipoprotein particle clearance 2/435 21/18722 0.0846361143487112 0.461938075141862 ANXA2/CNPY2 2 GO:0032516 positive regulation of phosphoprotein phosphatase activity 2/435 21/18722 0.0846361143487112 0.461938075141862 HSP90AB1/SLC39A10 2 GO:0038083 peptidyl-tyrosine autophosphorylation 2/435 21/18722 0.0846361143487112 0.461938075141862 EGFR/CAV1 2 GO:0044766 multi-organism transport 2/435 21/18722 0.0846361143487112 0.461938075141862 CTSL/CAV1 2 GO:0046597 negative regulation of viral entry into host cell 2/435 21/18722 0.0846361143487112 0.461938075141862 LY6E/SNX3 2 GO:0046823 negative regulation of nucleocytoplasmic transport 2/435 21/18722 0.0846361143487112 0.461938075141862 PARK7/FERMT1 2 GO:0048199 vesicle targeting, to, from or within Golgi 2/435 21/18722 0.0846361143487112 0.461938075141862 TMED9/PDCD6 2 GO:0090141 positive regulation of mitochondrial fission 2/435 21/18722 0.0846361143487112 0.461938075141862 FIS1/BNIP3 2 GO:0090189 regulation of branching involved in ureteric bud morphogenesis 2/435 21/18722 0.0846361143487112 0.461938075141862 MAGED1/TACSTD2 2 GO:0150105 protein localization to cell-cell junction 2/435 21/18722 0.0846361143487112 0.461938075141862 DSP/LSR 2 GO:1902579 multi-organism localization 2/435 21/18722 0.0846361143487112 0.461938075141862 CTSL/CAV1 2 GO:2000774 positive regulation of cellular senescence 2/435 21/18722 0.0846361143487112 0.461938075141862 HMGA1/YPEL3 2 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 6/435 131/18722 0.0852861094870722 0.46420513788218 PEG10/FBN2/LRP2/FBN1/EID2/CAV1 6 GO:1904950 negative regulation of establishment of protein localization 6/435 131/18722 0.0852861094870722 0.46420513788218 ERP29/PARK7/LMAN1/FERMT1/SNX3/ERLEC1 6 GO:0071322 cellular response to carbohydrate stimulus 7/435 163/18722 0.0863854033748544 0.46442731171995 SERPINF1/COLEC12/MPC2/HMGN3/BAD/FIS1/PHPT1 7 GO:0072331 signal transduction by p53 class mediator 7/435 163/18722 0.0863854033748544 0.46442731171995 PERP/RPL37/RPL23/RPS7/MIF/SHISA5/NPM1 7 GO:0042102 positive regulation of T cell proliferation 5/435 101/18722 0.0864014633302188 0.46442731171995 CD24/PNP/RPS3/CD46/CD55 5 GO:0003254 regulation of membrane depolarization 3/435 45/18722 0.0864680594062468 0.46442731171995 IFI6/PARP1/GJA5 3 GO:0035384 thioester biosynthetic process 3/435 45/18722 0.0864680594062468 0.46442731171995 ACSS1/TECR/MPC2 3 GO:0048538 thymus development 3/435 45/18722 0.0864680594062468 0.46442731171995 LMO4/SOD1/PRDX2 3 GO:0071616 acyl-CoA biosynthetic process 3/435 45/18722 0.0864680594062468 0.46442731171995 ACSS1/TECR/MPC2 3 GO:1904646 cellular response to amyloid-beta 3/435 45/18722 0.0864680594062468 0.46442731171995 PARP1/APP/GJA1 3 GO:0001707 mesoderm formation 4/435 72/18722 0.0865006137825633 0.46442731171995 BMP7/WLS/GJA1/ITGB4 4 GO:0070227 lymphocyte apoptotic process 4/435 72/18722 0.0865006137825633 0.46442731171995 SLC39A10/EFNA1/LGALS3/KDELR1 4 GO:0033157 regulation of intracellular protein transport 9/435 229/18722 0.0873157087602144 0.468168373393182 CDH1/BCAP31/HSP90AB1/PDCD5/PARK7/LMAN1/FERMT1/FIS1/ERLEC1 9 GO:0043588 skin development 10/435 263/18722 0.0878065208137165 0.470162926738669 CLDN4/ITGA6/EGFR/DSP/MET/ITGB4/LGR5/FERMT1/LAMA5/LSR 10 GO:0051271 negative regulation of cellular component movement 13/435 367/18722 0.0879796736596868 0.470453471177541 SERPINF1/SPINT2/GSTP1/ADGRG1/CDH1/FBLN1/GJA1/NR2F2/DAG1/CALR/MIF/TACSTD2/S1PR2 13 GO:0060537 muscle tissue development 14/435 403/18722 0.0888443247154312 0.474435887852849 BMP7/DSP/LRP2/CSRP2/GJA1/GJA5/NR2F2/MSX2/LY6E/CALR/LMNA/NDUFV2/CAV1/PRMT1 14 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 4/435 73/18722 0.0899271943347947 0.475659071182227 MPC2/HMGN3/BAD/PHPT1 4 GO:0072089 stem cell proliferation 4/435 73/18722 0.0899271943347947 0.475659071182227 FBLN1/GJA1/RNF43/FERMT1 4 GO:0046887 positive regulation of hormone secretion 6/435 133/18722 0.0901493673120814 0.475659071182227 EGFR/VAMP8/GJA1/MPC2/BAD/PHPT1 6 GO:0055010 ventricular cardiac muscle tissue morphogenesis 3/435 46/18722 0.0909823712906059 0.475659071182227 DSP/LRP2/LY6E 3 GO:1900271 regulation of long-term synaptic potentiation 3/435 46/18722 0.0909823712906059 0.475659071182227 MME/APP/NSG1 3 GO:0031099 regeneration 8/435 198/18722 0.0915248775760857 0.475659071182227 GSTP1/EGFR/RPS16/FOLR1/ANXA3/DAG1/NREP/CCND1 8 GO:0006907 pinocytosis 2/435 22/18722 0.0917179356360979 0.475659071182227 CLN3/CAV1 2 GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization 2/435 22/18722 0.0917179356360979 0.475659071182227 FOLR1/SPESP1 2 GO:0016137 glycoside metabolic process 2/435 22/18722 0.0917179356360979 0.475659071182227 FUCA1/AKR1B1 2 GO:0021854 hypothalamus development 2/435 22/18722 0.0917179356360979 0.475659071182227 NRP2/UQCRQ 2 GO:0032069 regulation of nuclease activity 2/435 22/18722 0.0917179356360979 0.475659071182227 RPS3/NPM1 2 GO:0033617 mitochondrial cytochrome c oxidase assembly 2/435 22/18722 0.0917179356360979 0.475659071182227 COA4/COX20 2 GO:0035584 calcium-mediated signaling using intracellular calcium source 2/435 22/18722 0.0917179356360979 0.475659071182227 BCAP31/FIS1 2 GO:0045048 protein insertion into ER membrane 2/435 22/18722 0.0917179356360979 0.475659071182227 WDR83OS/EMC7 2 GO:0045540 regulation of cholesterol biosynthetic process 2/435 22/18722 0.0917179356360979 0.475659071182227 SOD1/LPCAT3 2 GO:0050860 negative regulation of T cell receptor signaling pathway 2/435 22/18722 0.0917179356360979 0.475659071182227 LGALS3/PHPT1 2 GO:0051412 response to corticosterone 2/435 22/18722 0.0917179356360979 0.475659071182227 ATP2B1/CCND1 2 GO:0055093 response to hyperoxia 2/435 22/18722 0.0917179356360979 0.475659071182227 BNIP3/CAV1 2 GO:0099563 modification of synaptic structure 2/435 22/18722 0.0917179356360979 0.475659071182227 CLN3/MYH10 2 GO:0106118 regulation of sterol biosynthetic process 2/435 22/18722 0.0917179356360979 0.475659071182227 SOD1/LPCAT3 2 GO:1900120 regulation of receptor binding 2/435 22/18722 0.0917179356360979 0.475659071182227 PHLDA2/ANXA2 2 GO:1901032 negative regulation of response to reactive oxygen species 2/435 22/18722 0.0917179356360979 0.475659071182227 MET/PARK7 2 GO:0090277 positive regulation of peptide hormone secretion 5/435 103/18722 0.0920884639323251 0.476955565157344 EGFR/GJA1/MPC2/BAD/PHPT1 5 GO:0001508 action potential 6/435 134/18722 0.0926365141271507 0.479166910328282 DSP/GJA1/CLN3/GJA5/DSC2/CAV1 6 GO:0048332 mesoderm morphogenesis 4/435 74/18722 0.0934180421386143 0.481949403836372 BMP7/WLS/GJA1/ITGB4 4 GO:0120192 tight junction assembly 4/435 74/18722 0.0934180421386143 0.481949403836372 CLDN4/GJA1/CLDN7/LSR 4 GO:0007159 leukocyte cell-cell adhesion 13/435 371/18722 0.0936905208973216 0.48272576977956 CD24/BMP7/PRDX2/HSPD1/PNP/RPS3/LGALS3/BAD/ASS1/CD46/CD55/CAV1/CD47 13 GO:1903037 regulation of leukocyte cell-cell adhesion 12/435 336/18722 0.0940419714632217 0.483906477347163 CD24/PRDX2/HSPD1/PNP/RPS3/LGALS3/BAD/ASS1/CD46/CD55/CAV1/CD47 12 GO:1903076 regulation of protein localization to plasma membrane 5/435 104/18722 0.095002576378357 0.488214538609297 EGFR/VAMP8/CLN3/LGALS3/TMEM59 5 GO:1903034 regulation of response to wounding 7/435 167/18722 0.0951900290250883 0.488543378537321 CLDN4/ANXA2/PRDX2/GJA1/FERMT1/TNFRSF12A/CAV1 7 GO:0032386 regulation of intracellular transport 12/435 337/18722 0.0955877405635748 0.488708471398031 ANXA2/CDH1/BCAP31/HSP90AB1/PDCD5/PARK7/LMAN1/FERMT1/FIS1/SNX3/ERLEC1/REEP5 12 GO:0007595 lactation 3/435 47/18722 0.0955927108572342 0.488708471398031 CDO1/CCND1/CAV1 3 GO:0010799 regulation of peptidyl-threonine phosphorylation 3/435 47/18722 0.0955927108572342 0.488708471398031 BMP7/APP/S1PR2 3 GO:0050708 regulation of protein secretion 10/435 268/18722 0.0963939060371606 0.492168627340703 EGFR/WLS/GJA1/MYH10/ERP29/MPC2/HMGN3/BAD/KCNN4/PHPT1 10 GO:0061333 renal tubule morphogenesis 4/435 75/18722 0.0969722995968181 0.49448374936161 MAGED1/LGR5/LAMA5/TACSTD2 4 GO:2000241 regulation of reproductive process 7/435 168/18722 0.0974663604775957 0.496363434246906 SERPINF1/PHLDA2/BMP7/PRDX4/GJA1/C1QBP/CALR 7 GO:0043401 steroid hormone mediated signaling pathway 6/435 136/18722 0.0977209359623225 0.496961024945615 BMP7/PARP1/PARK7/CALR/PHB/SKP2 6 GO:0001919 regulation of receptor recycling 2/435 23/18722 0.0989651977905344 0.496961024945615 ANXA2/NSG1 2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules 2/435 23/18722 0.0989651977905344 0.496961024945615 CLDN4/CLDN7 2 GO:0021884 forebrain neuron development 2/435 23/18722 0.0989651977905344 0.496961024945615 NRP2/UQCRQ 2 GO:0035812 renal sodium excretion 2/435 23/18722 0.0989651977905344 0.496961024945615 COMT/ATP6V1B1 2 GO:0050765 negative regulation of phagocytosis 2/435 23/18722 0.0989651977905344 0.496961024945615 SNX3/CD47 2 GO:0051131 chaperone-mediated protein complex assembly 2/435 23/18722 0.0989651977905344 0.496961024945615 HSPD1/HSP90AB1 2 GO:0051882 mitochondrial depolarization 2/435 23/18722 0.0989651977905344 0.496961024945615 IFI6/PARP1 2 GO:0060353 regulation of cell adhesion molecule production 2/435 23/18722 0.0989651977905344 0.496961024945615 COLEC12/CAV1 2 GO:0071636 positive regulation of transforming growth factor beta production 2/435 23/18722 0.0989651977905344 0.496961024945615 FERMT1/CD46 2 GO:1900273 positive regulation of long-term synaptic potentiation 2/435 23/18722 0.0989651977905344 0.496961024945615 MME/APP 2 GO:0015804 neutral amino acid transport 3/435 48/18722 0.100296565638204 0.50003891323766 SLC43A2/SLC38A9/SLC1A5 3 GO:0032527 protein exit from endoplasmic reticulum 3/435 48/18722 0.100296565638204 0.50003891323766 HSP90B1/BCAP31/ERLEC1 3 GO:0045839 negative regulation of mitotic nuclear division 3/435 48/18722 0.100296565638204 0.50003891323766 BMP7/AURKAIP1/LCMT1 3 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 3/435 48/18722 0.100296565638204 0.50003891323766 PDIA3/TNFRSF12A/CAV1 3 GO:0006809 nitric oxide biosynthetic process 4/435 76/18722 0.100589076304568 0.50003891323766 HSP90AB1/ASS1/CAV1/CD47 4 GO:0008652 cellular amino acid biosynthetic process 4/435 76/18722 0.100589076304568 0.50003891323766 CLN3/ADI1/PARK7/ASS1 4 GO:0072028 nephron morphogenesis 4/435 76/18722 0.100589076304568 0.50003891323766 MAGED1/BMP7/LAMA5/TACSTD2 4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 4/435 76/18722 0.100589076304568 0.50003891323766 PERP/RPS7/MIF/SHISA5 4 GO:0002793 positive regulation of peptide secretion 5/435 106/18722 0.100970100754945 0.50004842138588 EGFR/GJA1/MPC2/BAD/PHPT1 5 GO:0071887 leukocyte apoptotic process 5/435 106/18722 0.100970100754945 0.50004842138588 CTSL/SLC39A10/EFNA1/LGALS3/KDELR1 5 GO:1905477 positive regulation of protein localization to membrane 5/435 106/18722 0.100970100754945 0.50004842138588 EGFR/CLN3/PDCD5/LGALS3/FIS1 5 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 14/435 412/18722 0.101439269815546 0.501743988325142 HSP90B1/PSMB5/BCAP31/HSP90AB1/PSMD7/PARK7/CALR/TBL1X/PSMD8/PSMC1/SKP2/DDB1/CAV1/ERLEC1 14 GO:0006650 glycerophospholipid metabolic process 11/435 306/18722 0.102197632787239 0.503726222609068 TMEM150A/CLN3/SERINC2/PRDX6/PISD/DBI/PYURF/STOML2/DNAJC19/HADHA/LPCAT3 11 GO:0034660 ncRNA metabolic process 16/435 485/18722 0.102211173461927 0.503726222609068 RPS21/RPS14/RPS27/RPS28/RPS16/RPS7/RPL10A/RPS19/RPS25/RPS17/RPL7A/NHP2/GTF2H5/LIN28B/TRMT112/IARS2 16 GO:0033673 negative regulation of kinase activity 9/435 237/18722 0.102349224912229 0.503726222609068 GSTP1/CDKN1C/PKIB/MLLT1/BMP7/NR2F2/PARK7/NPM1/CAV1 9 GO:1901617 organic hydroxy compound biosynthetic process 9/435 237/18722 0.102349224912229 0.503726222609068 ISYNA1/SOD1/SLC27A2/HSD17B1/PARK7/AKR1B1/CYB5R1/FDFT1/LPCAT3 9 GO:0048872 homeostasis of number of cells 10/435 272/18722 0.103608937894433 0.509292630122078 RPS14/SOD1/ADGRG1/PRDX1/RPS19/PRDX2/RPS17/TMEM14C/PRMT1/LPCAT3 10 GO:0036503 ERAD pathway 5/435 107/18722 0.104022682958217 0.509427916417903 HSP90B1/BCAP31/CALR/CAV1/ERLEC1 5 GO:0042303 molting cycle 5/435 107/18722 0.104022682958217 0.509427916417903 EGFR/LGR5/FERMT1/SNRPE/LAMA5 5 GO:0042633 hair cycle 5/435 107/18722 0.104022682958217 0.509427916417903 EGFR/LGR5/FERMT1/SNRPE/LAMA5 5 GO:0055117 regulation of cardiac muscle contraction 4/435 77/18722 0.104267450650241 0.509995429200251 DSP/GJA5/DSC2/CAV1 4 GO:0042110 T cell activation 16/435 487/18722 0.104924170452916 0.511496454292945 CD24/CTSL/SOD1/DDOST/PRDX2/HSPD1/PNP/RPS3/LGALS3/BAD/CD46/CD55/STOML2/KDELR1/CAV1/CD47 16 GO:0009066 aspartate family amino acid metabolic process 3/435 49/18722 0.105091386742523 0.511496454292945 SMS/ADI1/ASS1 3 GO:0014075 response to amine 3/435 49/18722 0.105091386742523 0.511496454292945 SOD1/GLDC/ASS1 3 GO:0072091 regulation of stem cell proliferation 3/435 49/18722 0.105091386742523 0.511496454292945 FBLN1/GJA1/FERMT1 3 GO:0051403 stress-activated MAPK cascade 9/435 239/18722 0.106325221452465 0.512034032652554 PAGE4/GSTP1/EGFR/PRDX1/DUSP9/ARL6IP5/APP/HACD3/PRMT1 9 GO:1903039 positive regulation of leukocyte cell-cell adhesion 9/435 239/18722 0.106325221452465 0.512034032652554 CD24/HSPD1/PNP/RPS3/BAD/CD46/CD55/CAV1/CD47 9 GO:0003148 outflow tract septum morphogenesis 2/435 24/18722 0.106366432863381 0.512034032652554 NRP2/LRP2 2 GO:0010155 regulation of proton transport 2/435 24/18722 0.106366432863381 0.512034032652554 NDUFA4/PARK7 2 GO:0010226 response to lithium ion 2/435 24/18722 0.106366432863381 0.512034032652554 CDH1/CALR 2 GO:0016486 peptide hormone processing 2/435 24/18722 0.106366432863381 0.512034032652554 CTSL/MME 2 GO:0044321 response to leptin 2/435 24/18722 0.106366432863381 0.512034032652554 LRP2/CCND1 2 GO:0051570 regulation of histone H3-K9 methylation 2/435 24/18722 0.106366432863381 0.512034032652554 DNMT1/LMNA 2 GO:0071577 zinc ion transmembrane transport 2/435 24/18722 0.106366432863381 0.512034032652554 SLC39A1/SLC39A10 2 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 4/435 78/18722 0.108006471397467 0.51553873018067 HSPD1/HSPE1/BAD/PDCD6 4 GO:0030500 regulation of bone mineralization 4/435 78/18722 0.108006471397467 0.51553873018067 FBN2/BMP7/ATRAID/ATP2B1 4 GO:0032024 positive regulation of insulin secretion 4/435 78/18722 0.108006471397467 0.51553873018067 GJA1/MPC2/BAD/PHPT1 4 GO:0034637 cellular carbohydrate biosynthetic process 4/435 78/18722 0.108006471397467 0.51553873018067 ISYNA1/UGP2/AGL/AKR1B1 4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 4/435 78/18722 0.108006471397467 0.51553873018067 IFI6/PRDX5/PARK7/LAMTOR5 4 GO:0043297 apical junction assembly 4/435 78/18722 0.108006471397467 0.51553873018067 CLDN4/GJA1/CLDN7/RHOC 4 GO:0070373 negative regulation of ERK1 and ERK2 cascade 4/435 78/18722 0.108006471397467 0.51553873018067 GSTP1/DUSP9/FBLN1/PHB 4 GO:0030177 positive regulation of Wnt signaling pathway 6/435 140/18722 0.108324395142016 0.515811831019203 RPS12/EGFR/WLS/LGR5/TBL1X/CAV1 6 GO:0046165 alcohol biosynthetic process 6/435 140/18722 0.108324395142016 0.515811831019203 ISYNA1/SOD1/PARK7/AKR1B1/FDFT1/LPCAT3 6 GO:0006694 steroid biosynthetic process 7/435 173/18722 0.109293229329619 0.519799649588106 SOD1/SLC27A2/HSD17B1/AKR1B1/CYB5R1/FDFT1/LPCAT3 7 GO:0050873 brown fat cell differentiation 3/435 50/18722 0.109974594214035 0.520537642709252 BMP7/ADRB1/BNIP3 3 GO:0060688 regulation of morphogenesis of a branching structure 3/435 50/18722 0.109974594214035 0.520537642709252 MAGED1/BMP7/TACSTD2 3 GO:0070231 T cell apoptotic process 3/435 50/18722 0.109974594214035 0.520537642709252 EFNA1/LGALS3/KDELR1 3 GO:0071709 membrane assembly 3/435 50/18722 0.109974594214035 0.520537642709252 ANXA2/S100A10/CAV1 3 GO:0048284 organelle fusion 6/435 141/18722 0.111064430387658 0.525068041868532 ANXA2/VAMP8/CLN3/FIS1/STOML2/BNIP3 6 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 4/435 79/18722 0.111805159246855 0.527939158878049 P4HB/S100A10/C1QBP/CALR 4 GO:1901215 negative regulation of neuron death 8/435 208/18722 0.11282969646408 0.529042606587566 SERPINF1/SOD1/HSPD1/NENF/CLN3/HSP90AB1/PARK7/PSMC1 8 GO:1905954 positive regulation of lipid localization 5/435 110/18722 0.113450333321106 0.529042606587566 ANXA2/DBI/HILPDA/CAV1/LPCAT3 5 GO:0014706 striated muscle tissue development 13/435 384/18722 0.113795689718982 0.529042606587566 BMP7/DSP/LRP2/GJA1/GJA5/NR2F2/MSX2/LY6E/CALR/LMNA/NDUFV2/CAV1/PRMT1 13 GO:0007009 plasma membrane organization 6/435 142/18722 0.113839614196871 0.529042606587566 SOD1/DEGS1/FOLR1/SPESP1/CLN3/CAV1 6 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 2/435 25/18722 0.113910614306951 0.529042606587566 GJA1/GJA5 2 GO:0003094 glomerular filtration 2/435 25/18722 0.113910614306951 0.529042606587566 GJA1/GJA5 2 GO:0006658 phosphatidylserine metabolic process 2/435 25/18722 0.113910614306951 0.529042606587566 SERINC2/LPCAT3 2 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 2/435 25/18722 0.113910614306951 0.529042606587566 PRDX2/CD55 2 GO:0048143 astrocyte activation 2/435 25/18722 0.113910614306951 0.529042606587566 EGFR/APP 2 GO:0140448 signaling receptor ligand precursor processing 2/435 25/18722 0.113910614306951 0.529042606587566 CTSL/MME 2 GO:1903792 negative regulation of anion transport 2/435 25/18722 0.113910614306951 0.529042606587566 ARL6IP5/SLC43A2 2 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA 2/435 25/18722 0.113910614306951 0.529042606587566 EGFR/LIN28B 2 GO:1903901 negative regulation of viral life cycle 2/435 25/18722 0.113910614306951 0.529042606587566 LY6E/SNX3 2 GO:1903959 regulation of anion transmembrane transport 2/435 25/18722 0.113910614306951 0.529042606587566 ARL6IP5/SLC43A2 2 GO:0045104 intermediate filament cytoskeleton organization 3/435 51/18722 0.114943582108139 0.532054559088419 KRT18/SOD1/DSP 3 GO:0065002 intracellular protein transmembrane transport 3/435 51/18722 0.114943582108139 0.532054559088419 HSPD1/ROMO1/DNAJC19 3 GO:0031349 positive regulation of defense response 10/435 278/18722 0.115002061257523 0.532054559088419 EGFR/VAMP8/TGM2/RPS19/HSPD1/APP/GJA1/PARK7/CADM1/CD47 10 GO:1902905 positive regulation of supramolecular fiber organization 8/435 209/18722 0.115096968051475 0.532054559088419 MET/APP/RPS3/S100A10/DSTN/RHOC/WASF2/CD47 8 GO:0071229 cellular response to acid chemical 4/435 80/18722 0.115662508376013 0.532801566523729 DNMT1/ASS1/LAMTOR5/SLC38A9 4 GO:0120193 tight junction organization 4/435 80/18722 0.115662508376013 0.532801566523729 CLDN4/GJA1/CLDN7/LSR 4 GO:1901264 carbohydrate derivative transport 4/435 80/18722 0.115662508376013 0.532801566523729 GJA1/CLN3/SLC19A1/CD47 4 GO:0006898 receptor-mediated endocytosis 9/435 244/18722 0.116641273733139 0.536100731330148 CTSL/ANXA2/LRPAP1/FOLR1/LRP2/CLTA/CLN3/AP1S1/CAV1 9 GO:0006865 amino acid transport 6/435 143/18722 0.116649666331882 0.536100731330148 ARL6IP5/GJA1/CLN3/SLC43A2/SLC38A9/SLC1A5 6 GO:0045860 positive regulation of protein kinase activity 13/435 386/18722 0.117097613737372 0.53753510157631 CD24/MAGED1/EGFR/RPLP1/HSP90AB1/RPS3/EFNA1/ERP29/PARK7/DAG1/PHB/NPM1/CCND1 13 GO:0070663 regulation of leukocyte proliferation 9/435 245/18722 0.118768371836574 0.542412991872256 CD24/GSTP1/PNP/RPS3/SLC39A10/LGALS3/CD46/MIF/CD55 9 GO:0055074 calcium ion homeostasis 15/435 460/18722 0.118893266337413 0.542412991872256 CD24/TGM2/APP/HSP90B1/GJA1/CLN3/BCAP31/ATP6V1B1/CALR/CD55/FIS1/STOML2/ATP2B1/BNIP3/CAV1 15 GO:0071453 cellular response to oxygen levels 7/435 177/18722 0.119280186295161 0.542412991872256 BMP7/P4HB/HILPDA/BAD/LMNA/BNIP3/CAV1 7 GO:0033135 regulation of peptidyl-serine phosphorylation 6/435 144/18722 0.119494295266145 0.542412991872256 EGFR/APP/HSP90AB1/PARK7/MIF/CAV1 6 GO:0001942 hair follicle development 4/435 81/18722 0.119577487956605 0.542412991872256 EGFR/LGR5/FERMT1/LAMA5 4 GO:0010833 telomere maintenance via telomere lengthening 4/435 81/18722 0.119577487956605 0.542412991872256 PKIB/PARP1/HSP90AB1/NHP2 4 GO:0046209 nitric oxide metabolic process 4/435 81/18722 0.119577487956605 0.542412991872256 HSP90AB1/ASS1/CAV1/CD47 4 GO:0043406 positive regulation of MAP kinase activity 5/435 112/18722 0.119955514093323 0.542412991872256 CD24/MAGED1/EGFR/RPS3/ERP29 5 GO:0031103 axon regeneration 3/435 52/18722 0.119995723298645 0.542412991872256 FOLR1/DAG1/NREP 3 GO:0043090 amino acid import 3/435 52/18722 0.119995723298645 0.542412991872256 ARL6IP5/SLC43A2/SLC1A5 3 GO:0045103 intermediate filament-based process 3/435 52/18722 0.119995723298645 0.542412991872256 KRT18/SOD1/DSP 3 GO:0051496 positive regulation of stress fiber assembly 3/435 52/18722 0.119995723298645 0.542412991872256 S100A10/RHOC/CD47 3 GO:1903426 regulation of reactive oxygen species biosynthetic process 3/435 52/18722 0.119995723298645 0.542412991872256 PAGE4/HSPD1/PARK7 3 GO:0051402 neuron apoptotic process 9/435 246/18722 0.120916573586988 0.542412991872256 SOD1/PARP1/HSPD1/APP/CLN3/HSP90AB1/PARK7/FIS1/BNIP3 9 GO:0001963 synaptic transmission, dopaminergic 2/435 26/18722 0.121587142732042 0.542412991872256 SLC6A4/PARK7 2 GO:0002026 regulation of the force of heart contraction 2/435 26/18722 0.121587142732042 0.542412991872256 ADRB1/CAV1 2 GO:0002407 dendritic cell chemotaxis 2/435 26/18722 0.121587142732042 0.542412991872256 C1QBP/CALR 2 GO:0008535 respiratory chain complex IV assembly 2/435 26/18722 0.121587142732042 0.542412991872256 COA4/COX20 2 GO:0043094 cellular metabolic compound salvage 2/435 26/18722 0.121587142732042 0.542412991872256 PNP/ADI1 2 GO:0045026 plasma membrane fusion 2/435 26/18722 0.121587142732042 0.542412991872256 FOLR1/SPESP1 2 GO:0046697 decidualization 2/435 26/18722 0.121587142732042 0.542412991872256 BSG/GJA1 2 GO:0060037 pharyngeal system development 2/435 26/18722 0.121587142732042 0.542412991872256 FOLR1/BMP7 2 GO:0060352 cell adhesion molecule production 2/435 26/18722 0.121587142732042 0.542412991872256 COLEC12/CAV1 2 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA 2/435 26/18722 0.121587142732042 0.542412991872256 EGFR/LIN28B 2 GO:0097205 renal filtration 2/435 26/18722 0.121587142732042 0.542412991872256 GJA1/GJA5 2 GO:0009749 response to glucose 8/435 212/18722 0.122045066091753 0.543842710050751 SERPINF1/GJA1/MPC2/HMGN3/BAD/FIS1/PHPT1/TXN2 8 GO:0006066 alcohol metabolic process 12/435 353/18722 0.122404011993851 0.544828656310086 ISYNA1/SOD1/ACSS1/APP/IDH1/ADH5/PARK7/NUDT4/AKR1B1/ACADVL/FDFT1/LPCAT3 12 GO:1903532 positive regulation of secretion by cell 10/435 282/18722 0.122973436224776 0.546748187799371 EGFR/VAMP8/WLS/GJA1/SLC6A4/MYH10/MPC2/BAD/KCNN4/PHPT1 10 GO:2001057 reactive nitrogen species metabolic process 4/435 82/18722 0.123549043647307 0.548690870608746 HSP90AB1/ASS1/CAV1/CD47 4 GO:0070661 leukocyte proliferation 11/435 318/18722 0.12397690270256 0.549973771293754 CD24/GSTP1/PRDX2/HSPD1/PNP/RPS3/SLC39A10/LGALS3/CD46/MIF/CD55 11 GO:0048568 embryonic organ development 14/435 427/18722 0.124733680098698 0.552603767879036 EFEMP1/SPINT2/SPINT1/PHLDA2/SOD1/FBN2/FOLR1/BMP7/KRT8/SLC39A1/FBN1/EFNA1/NR2F2/ATP6V1B1 14 GO:0034381 plasma lipoprotein particle clearance 3/435 53/18722 0.12512837402568 0.552603767879036 ANXA2/LRPAP1/CNPY2 3 GO:0045806 negative regulation of endocytosis 3/435 53/18722 0.12512837402568 0.552603767879036 LRPAP1/LGALS3/CAV1 3 GO:1903202 negative regulation of oxidative stress-induced cell death 3/435 53/18722 0.12512837402568 0.552603767879036 PAGE4/MET/PARK7 3 GO:0040013 negative regulation of locomotion 13/435 391/18722 0.125593666883402 0.554040289696345 SERPINF1/SPINT2/GSTP1/ADGRG1/CDH1/FBLN1/GJA1/NR2F2/DAG1/CALR/MIF/TACSTD2/S1PR2 13 GO:0008202 steroid metabolic process 11/435 319/18722 0.125900571488859 0.554158577732388 SOD1/COMT/SLC27A2/LRP2/HSD17B1/APP/AKR1B1/CYB5R1/ACADVL/FDFT1/LPCAT3 11 GO:1901214 regulation of neuron death 11/435 319/18722 0.125900571488859 0.554158577732388 SERPINF1/SOD1/PARP1/HSPD1/NENF/CLN3/HSP90AB1/PARK7/BAD/FIS1/PSMC1 11 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 5/435 114/18722 0.126631928489793 0.556758378926789 CDKN1C/BMP7/PARP1/HSP90AB1/FERMT1 5 GO:0022409 positive regulation of cell-cell adhesion 10/435 284/18722 0.127070445810102 0.557712132425508 CD24/BMP7/HSPD1/PNP/RPS3/BAD/CD46/CD55/CAV1/CD47 10 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 9/435 249/18722 0.127486868964489 0.557712132425508 GSTP1/TGM2/WLS/TMED4/GJA1/S100A13/SHISA5/LAMTOR5/RHOC 9 GO:0016042 lipid catabolic process 11/435 320/18722 0.127840739804904 0.557712132425508 ECHS1/ECH1/SLC27A2/ECI2/IDH1/PRDX6/ECI1/FUCA1/ACADVL/ETFA/HADHA 11 GO:1902652 secondary alcohol metabolic process 6/435 147/18722 0.128232563466578 0.557712132425508 SOD1/APP/IDH1/ACADVL/FDFT1/LPCAT3 6 GO:0000469 cleavage involved in rRNA processing 2/435 27/18722 0.129385832086585 0.557712132425508 RPS21/NHP2 2 GO:0003171 atrioventricular valve development 2/435 27/18722 0.129385832086585 0.557712132425508 GJA5/EFNA1 2 GO:0009651 response to salt stress 2/435 27/18722 0.129385832086585 0.557712132425508 HSP90AB1/AKR1B1 2 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 2/435 27/18722 0.129385832086585 0.557712132425508 APP/CCND1 2 GO:0018195 peptidyl-arginine modification 2/435 27/18722 0.129385832086585 0.557712132425508 PARK7/PRMT1 2 GO:0035235 ionotropic glutamate receptor signaling pathway 2/435 27/18722 0.129385832086585 0.557712132425508 APP/CLN3 2 GO:0039529 RIG-I signaling pathway 2/435 27/18722 0.129385832086585 0.557712132425508 C1QBP/PHB 2 GO:0042104 positive regulation of activated T cell proliferation 2/435 27/18722 0.129385832086585 0.557712132425508 CD24/RPS3 2 GO:0042402 cellular biogenic amine catabolic process 2/435 27/18722 0.129385832086585 0.557712132425508 COMT/ALDH7A1 2 GO:0051953 negative regulation of amine transport 2/435 27/18722 0.129385832086585 0.557712132425508 ARL6IP5/SLC43A2 2 GO:0070861 regulation of protein exit from endoplasmic reticulum 2/435 27/18722 0.129385832086585 0.557712132425508 BCAP31/ERLEC1 2 GO:1902883 negative regulation of response to oxidative stress 2/435 27/18722 0.129385832086585 0.557712132425508 MET/PARK7 2 GO:1903203 regulation of oxidative stress-induced neuron death 2/435 27/18722 0.129385832086585 0.557712132425508 PARP1/PARK7 2 GO:1903205 regulation of hydrogen peroxide-induced cell death 2/435 27/18722 0.129385832086585 0.557712132425508 MET/PARK7 2 GO:0071675 regulation of mononuclear cell migration 5/435 115/18722 0.130032975255614 0.559891711737177 APP/C1QBP/LGALS3/CALR/CD47 5 GO:0070228 regulation of lymphocyte apoptotic process 3/435 54/18722 0.130338878195195 0.560598848933027 SLC39A10/EFNA1/LGALS3 3 GO:0010921 regulation of phosphatase activity 4/435 84/18722 0.13165755720963 0.563819214154228 HSP90B1/HSP90AB1/SLC39A10/LGALS3 4 GO:0022404 molting cycle process 4/435 84/18722 0.13165755720963 0.563819214154228 EGFR/LGR5/FERMT1/LAMA5 4 GO:0022405 hair cycle process 4/435 84/18722 0.13165755720963 0.563819214154228 EGFR/LGR5/FERMT1/LAMA5 4 GO:0032370 positive regulation of lipid transport 4/435 84/18722 0.13165755720963 0.563819214154228 ANXA2/DBI/CAV1/LPCAT3 4 GO:0009306 protein secretion 12/435 359/18722 0.133458505690147 0.569139203801683 FAM3B/EGFR/WLS/GJA1/MYH10/ERP29/PARK7/MPC2/HMGN3/BAD/KCNN4/PHPT1 12 GO:0006720 isoprenoid metabolic process 5/435 116/18722 0.133475153178661 0.569139203801683 EGFR/LRP2/ADH5/AKR1B1/FDFT1 5 GO:0030518 intracellular steroid hormone receptor signaling pathway 5/435 116/18722 0.133475153178661 0.569139203801683 PARP1/PARK7/CALR/PHB/SKP2 5 GO:0033559 unsaturated fatty acid metabolic process 5/435 116/18722 0.133475153178661 0.569139203801683 GSTP1/DEGS1/AKR1B1/ATP6V1B1/MIF 5 GO:0009411 response to UV 6/435 149/18722 0.134225129612573 0.571020338649463 EGFR/PARP1/MME/NPM1/DDB1/CCND1 6 GO:0090257 regulation of muscle system process 9/435 252/18722 0.134243565709917 0.571020338649463 SOD1/DSP/PARP1/GJA5/DSC2/DAG1/LMNA/ATP2B1/CAV1 9 GO:0032970 regulation of actin filament-based process 13/435 396/18722 0.134431175769734 0.571020338649463 DSP/MET/GJA5/S100A10/DSC2/DSTN/TACSTD2/PHPT1/KANK4/CAV1/RHOC/WASF2/CD47 13 GO:0035592 establishment of protein localization to extracellular region 12/435 360/18722 0.135352826182155 0.571020338649463 FAM3B/EGFR/WLS/GJA1/MYH10/ERP29/PARK7/MPC2/HMGN3/BAD/KCNN4/PHPT1 12 GO:0046651 lymphocyte proliferation 10/435 288/18722 0.135484132260569 0.571020338649463 CD24/PRDX2/HSPD1/PNP/RPS3/SLC39A10/LGALS3/CD46/MIF/CD55 10 GO:0003229 ventricular cardiac muscle tissue development 3/435 55/18722 0.135624571440221 0.571020338649463 DSP/LRP2/LY6E 3 GO:0006414 translational elongation 3/435 55/18722 0.135624571440221 0.571020338649463 RPLP1/RPLP2/TUFM 3 GO:0042220 response to cocaine 3/435 55/18722 0.135624571440221 0.571020338649463 TGM2/HSPD1/HSP90AB1 3 GO:0043331 response to dsRNA 3/435 55/18722 0.135624571440221 0.571020338649463 COLEC12/NPM1/CAV1 3 GO:0044091 membrane biogenesis 3/435 55/18722 0.135624571440221 0.571020338649463 ANXA2/S100A10/CAV1 3 GO:0032092 positive regulation of protein binding 4/435 85/18722 0.135792301912849 0.571020338649463 ANXA2/APP/HSP90AB1/CAV1 4 GO:0097006 regulation of plasma lipoprotein particle levels 4/435 85/18722 0.135792301912849 0.571020338649463 ANXA2/LRPAP1/CNPY2/LPCAT3 4 GO:0098773 skin epidermis development 4/435 85/18722 0.135792301912849 0.571020338649463 EGFR/LGR5/FERMT1/LAMA5 4 GO:0007163 establishment or maintenance of cell polarity 8/435 218/18722 0.136587489948299 0.573084196662381 SPINT2/PDLIM1/GJA1/HSP90AB1/LMNA/FERMT1/AMOT/RHOC 8 GO:0006829 zinc ion transport 2/435 28/18722 0.137296896243603 0.573084196662381 SLC39A1/SLC39A10 2 GO:0006972 hyperosmotic response 2/435 28/18722 0.137296896243603 0.573084196662381 SLC2A1/AKR1B1 2 GO:0015740 C4-dicarboxylate transport 2/435 28/18722 0.137296896243603 0.573084196662381 SLC13A3/SLC1A5 2 GO:0032801 receptor catabolic process 2/435 28/18722 0.137296896243603 0.573084196662381 ANXA2/RNF43 2 GO:0060765 regulation of androgen receptor signaling pathway 2/435 28/18722 0.137296896243603 0.573084196662381 PARK7/PHB 2 GO:1903779 regulation of cardiac conduction 2/435 28/18722 0.137296896243603 0.573084196662381 GJA5/ATP2B1 2 GO:2000117 negative regulation of cysteine-type endopeptidase activity 4/435 86/18722 0.139979199191459 0.58171937441269 IFI6/PRDX5/PARK7/LAMTOR5 4 GO:0048754 branching morphogenesis of an epithelial tube 6/435 151/18722 0.140348104656432 0.58171937441269 MAGED1/BMP7/MET/DAG1/LAMA5/TACSTD2 6 GO:0071333 cellular response to glucose stimulus 6/435 151/18722 0.140348104656432 0.58171937441269 SERPINF1/MPC2/HMGN3/BAD/FIS1/PHPT1 6 GO:0071456 cellular response to hypoxia 6/435 151/18722 0.140348104656432 0.58171937441269 BMP7/P4HB/HILPDA/BAD/LMNA/BNIP3 6 GO:0022612 gland morphogenesis 5/435 118/18722 0.140480533446113 0.58171937441269 BMP7/TGM2/DAG1/LAMA5/CAV1 5 GO:0051101 regulation of DNA binding 5/435 118/18722 0.140480533446113 0.58171937441269 PARP1/PARK7/MSX2/ZNF593/LAMTOR5 5 GO:0007369 gastrulation 7/435 185/18722 0.140605653317575 0.58171937441269 BMP7/WLS/GJA1/ITGB4/DAG1/AMOT/ITGB5 7 GO:0001658 branching involved in ureteric bud morphogenesis 3/435 56/18722 0.140982784953695 0.58171937441269 MAGED1/LAMA5/TACSTD2 3 GO:0043388 positive regulation of DNA binding 3/435 56/18722 0.140982784953695 0.58171937441269 PARP1/PARK7/LAMTOR5 3 GO:0051784 negative regulation of nuclear division 3/435 56/18722 0.140982784953695 0.58171937441269 BMP7/AURKAIP1/LCMT1 3 GO:1904645 response to amyloid-beta 3/435 56/18722 0.140982784953695 0.58171937441269 PARP1/APP/GJA1 3 GO:0050673 epithelial cell proliferation 14/435 437/18722 0.141839652675599 0.584631017386775 SERPINF1/MAGED1/EGFR/CDKN1C/NRP2/GJA1/LGR5/NR2F2/MYDGF/BAD/FERMT1/CCND1/CAV1/PDCD6 14 GO:0032943 mononuclear cell proliferation 10/435 291/18722 0.141983929165704 0.584631017386775 CD24/PRDX2/HSPD1/PNP/RPS3/SLC39A10/LGALS3/CD46/MIF/CD55 10 GO:0016125 sterol metabolic process 6/435 152/18722 0.143457581150729 0.590084873818538 SOD1/APP/CYB5R1/ACADVL/FDFT1/LPCAT3 6 GO:0030111 regulation of Wnt signaling pathway 11/435 328/18722 0.143948460044095 0.59014173655866 RPS12/EGFR/FOLR1/WLS/APP/LGR5/RNF43/FERMT1/SNX3/TBL1X/CAV1 11 GO:0008406 gonad development 8/435 221/18722 0.144173630365425 0.59014173655866 SOD1/ADGRG1/LRP2/PRDX4/IDH1/NR2F2/EIF2S2/CCND1 8 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 8/435 221/18722 0.144173630365425 0.59014173655866 RPL23/RPS7/BCAP31/HSP90AB1/EFNA1/PARK7/PSMC1/CAV1 8 GO:0016101 diterpenoid metabolic process 4/435 87/18722 0.144217098623256 0.59014173655866 EGFR/LRP2/ADH5/AKR1B1 4 GO:1903578 regulation of ATP metabolic process 4/435 87/18722 0.144217098623256 0.59014173655866 PARP1/APP/COX7A2/FIS1 4 GO:0009310 amine catabolic process 2/435 29/18722 0.145310935986988 0.590951052107411 COMT/ALDH7A1 2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity 2/435 29/18722 0.145310935986988 0.590951052107411 EGFR/CCND1 2 GO:0048265 response to pain 2/435 29/18722 0.145310935986988 0.590951052107411 VWA1/COMT 2 GO:0050686 negative regulation of mRNA processing 2/435 29/18722 0.145310935986988 0.590951052107411 C1QBP/NPM1 2 GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 2/435 29/18722 0.145310935986988 0.590951052107411 RPS7/MIF 2 GO:1903902 positive regulation of viral life cycle 2/435 29/18722 0.145310935986988 0.590951052107411 P4HB/DDB1 2 GO:0005996 monosaccharide metabolic process 9/435 257/18722 0.145910596847151 0.592780525384164 PHLDA2/SLC2A1/DCXR/FUCA1/AKR1B1/BAD/DDB1/RPIA/LCMT1 9 GO:0006695 cholesterol biosynthetic process 3/435 57/18722 0.146410849102277 0.593593985550933 SOD1/FDFT1/LPCAT3 3 GO:1902653 secondary alcohol biosynthetic process 3/435 57/18722 0.146410849102277 0.593593985550933 SOD1/FDFT1/LPCAT3 3 GO:0071331 cellular response to hexose stimulus 6/435 153/18722 0.146598544370838 0.593746612154969 SERPINF1/MPC2/HMGN3/BAD/FIS1/PHPT1 6 GO:0001701 in utero embryonic development 12/435 367/18722 0.149021138715778 0.602438628753493 SPINT2/SPINT1/PHLDA2/BMP7/KRT8/SLC39A1/NR2F2/LY6E/AMOT/SF3B6/EIF2S2/PRMT1 12 GO:0001906 cell killing 7/435 188/18722 0.149049132562464 0.602438628753493 PRDX1/RPS19/CD59/HSP90AB1/ROMO1/CADM1/CD55 7 GO:0071326 cellular response to monosaccharide stimulus 6/435 154/18722 0.149770603928235 0.604737020146967 SERPINF1/MPC2/HMGN3/BAD/FIS1/PHPT1 6 GO:0001704 formation of primary germ layer 5/435 121/18722 0.15128194263749 0.609595363560641 BMP7/WLS/GJA1/ITGB4/ITGB5 5 GO:0003206 cardiac chamber morphogenesis 5/435 121/18722 0.15128194263749 0.609595363560641 NRP2/BMP7/DSP/LRP2/LY6E 5 GO:0001954 positive regulation of cell-matrix adhesion 3/435 58/18722 0.151906096830308 0.609650976864782 S100A10/DAG1/FERMT1 3 GO:0002931 response to ischemia 3/435 58/18722 0.151906096830308 0.609650976864782 HSPD1/GJA1/CAV1 3 GO:0010043 response to zinc ion 3/435 58/18722 0.151906096830308 0.609650976864782 PARP1/GGH/ASS1 3 GO:0043410 positive regulation of MAPK cascade 15/435 480/18722 0.151912020012301 0.609650976864782 CD24/SOD1/MAGED1/EGFR/ARL6IP5/PRDX2/APP/NENF/RPS3/EFNA1/ERP29/MYDGF/MIF/PHB/PRMT1 15 GO:0007202 activation of phospholipase C activity 2/435 30/18722 0.153418926383913 0.610743150604771 EGFR/PHB 2 GO:0036296 response to increased oxygen levels 2/435 30/18722 0.153418926383913 0.610743150604771 BNIP3/CAV1 2 GO:0044788 modulation by host of viral process 2/435 30/18722 0.153418926383913 0.610743150604771 PPIB/PHB 2 GO:0045070 positive regulation of viral genome replication 2/435 30/18722 0.153418926383913 0.610743150604771 HACD3/DDB1 2 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway 2/435 30/18722 0.153418926383913 0.610743150604771 LGALS3/PHPT1 2 GO:0060674 placenta blood vessel development 2/435 30/18722 0.153418926383913 0.610743150604771 SPINT1/NR2F2 2 GO:0070229 negative regulation of lymphocyte apoptotic process 2/435 30/18722 0.153418926383913 0.610743150604771 SLC39A10/EFNA1 2 GO:1903579 negative regulation of ATP metabolic process 2/435 30/18722 0.153418926383913 0.610743150604771 PARP1/FIS1 2 GO:0016055 Wnt signaling pathway 14/435 444/18722 0.154544094747422 0.613611309817459 CD24/RPS12/EGFR/FOLR1/WLS/APP/LGR5/RNF43/FERMT1/SNX3/TBL1X/DDB1/CCND1/CAV1 14 GO:0010001 glial cell differentiation 8/435 225/18722 0.15460461862219 0.613611309817459 SPINT1/GSTP1/SOD1/EGFR/APP/ITGB4/DAG1/BNIP3 8 GO:0050670 regulation of lymphocyte proliferation 8/435 225/18722 0.15460461862219 0.613611309817459 CD24/PNP/RPS3/SLC39A10/LGALS3/CD46/MIF/CD55 8 GO:0009755 hormone-mediated signaling pathway 7/435 190/18722 0.154807990413607 0.613802823714071 BMP7/PARP1/LGR5/PARK7/CALR/PHB/SKP2 7 GO:0034644 cellular response to UV 4/435 90/18722 0.157225086706762 0.61631299226067 PARP1/MME/NPM1/DDB1 4 GO:0035304 regulation of protein dephosphorylation 4/435 90/18722 0.157225086706762 0.61631299226067 HSP90B1/HSP90AB1/SLC39A10/LGALS3 4 GO:0042475 odontogenesis of dentin-containing tooth 4/435 90/18722 0.157225086706762 0.61631299226067 PERP/BSG/BMP7/LAMA5 4 GO:0061097 regulation of protein tyrosine kinase activity 4/435 90/18722 0.157225086706762 0.61631299226067 CD24/APP/EFNA1/CAV1 4 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 4/435 90/18722 0.157225086706762 0.61631299226067 GSTP1/DNMT1/GJA1/S1PR2 4 GO:0006486 protein glycosylation 8/435 226/18722 0.157267553921233 0.61631299226067 GALNT11/TUSC3/EXTL2/DDOST/RPN2/OSTC/TMEM59/TMEM258 8 GO:0043413 macromolecule glycosylation 8/435 226/18722 0.157267553921233 0.61631299226067 GALNT11/TUSC3/EXTL2/DDOST/RPN2/OSTC/TMEM59/TMEM258 8 GO:0006767 water-soluble vitamin metabolic process 3/435 59/18722 0.157465866862658 0.61631299226067 SLC2A1/FOLR1/SLC19A1 3 GO:0032768 regulation of monooxygenase activity 3/435 59/18722 0.157465866862658 0.61631299226067 EGFR/PARK7/CAV1 3 GO:0043407 negative regulation of MAP kinase activity 3/435 59/18722 0.157465866862658 0.61631299226067 GSTP1/BMP7/CAV1 3 GO:0051055 negative regulation of lipid biosynthetic process 3/435 59/18722 0.157465866862658 0.61631299226067 SOD1/ACADVL/ORMDL1 3 GO:0071806 protein transmembrane transport 3/435 59/18722 0.157465866862658 0.61631299226067 HSPD1/ROMO1/DNAJC19 3 GO:0090303 positive regulation of wound healing 3/435 59/18722 0.157465866862658 0.61631299226067 CLDN4/PRDX2/FERMT1 3 GO:0031330 negative regulation of cellular catabolic process 9/435 262/18722 0.158070908883317 0.617973534998993 ANXA2/RPL23/RPS7/SLIRP/MET/HSP90AB1/EFNA1/PARK7/ATRAID 9 GO:0198738 cell-cell signaling by wnt 14/435 446/18722 0.158281872803463 0.617973534998993 CD24/RPS12/EGFR/FOLR1/WLS/APP/LGR5/RNF43/FERMT1/SNX3/TBL1X/DDB1/CCND1/CAV1 14 GO:0003231 cardiac ventricle development 5/435 123/18722 0.158670991043462 0.617973534998993 LMO4/DSP/LRP2/GJA5/LY6E 5 GO:0006690 icosanoid metabolic process 5/435 123/18722 0.158670991043462 0.617973534998993 MGST3/GSTP1/AKR1B1/ATP6V1B1/MIF 5 GO:0050852 T cell receptor signaling pathway 5/435 123/18722 0.158670991043462 0.617973534998993 RPS3/LGALS3/STOML2/KCNN4/PHPT1 5 GO:0032944 regulation of mononuclear cell proliferation 8/435 227/18722 0.15995216414661 0.621712200453875 CD24/PNP/RPS3/SLC39A10/LGALS3/CD46/MIF/CD55 8 GO:0045137 development of primary sexual characteristics 8/435 227/18722 0.15995216414661 0.621712200453875 SOD1/ADGRG1/LRP2/PRDX4/IDH1/NR2F2/EIF2S2/CCND1 8 GO:0032872 regulation of stress-activated MAPK cascade 7/435 192/18722 0.160668191041272 0.621712200453875 PAGE4/GSTP1/EGFR/PRDX1/ARL6IP5/APP/PRMT1 7 GO:0007190 activation of adenylate cyclase activity 2/435 31/18722 0.161612204533007 0.621712200453875 ADRB1/LGR5 2 GO:0036474 cell death in response to hydrogen peroxide 2/435 31/18722 0.161612204533007 0.621712200453875 MET/PARK7 2 GO:0090183 regulation of kidney development 2/435 31/18722 0.161612204533007 0.621712200453875 MAGED1/TACSTD2 2 GO:1900027 regulation of ruffle assembly 2/435 31/18722 0.161612204533007 0.621712200453875 TACSTD2/CAV1 2 GO:0001657 ureteric bud development 4/435 91/18722 0.16165520761714 0.621712200453875 MAGED1/BMP7/LAMA5/TACSTD2 4 GO:0072080 nephron tubule development 4/435 91/18722 0.16165520761714 0.621712200453875 CD24/MAGED1/LAMA5/TACSTD2 4 GO:1990874 vascular associated smooth muscle cell proliferation 4/435 91/18722 0.16165520761714 0.621712200453875 GSTP1/DNMT1/GJA1/S1PR2 4 GO:0006874 cellular calcium ion homeostasis 14/435 448/18722 0.162066863514646 0.621712200453875 CD24/TGM2/APP/HSP90B1/GJA1/CLN3/BCAP31/CALR/CD55/FIS1/STOML2/ATP2B1/BNIP3/CAV1 14 GO:0010508 positive regulation of autophagy 5/435 124/18722 0.162419966772419 0.621712200453875 PARK7/BAD/TMEM59/SCOC/BNIP3 5 GO:0072503 cellular divalent inorganic cation homeostasis 15/435 486/18722 0.162698756490401 0.621712200453875 CD24/TGM2/APP/HSP90B1/GJA1/CLN3/BCAP31/SLC39A10/CALR/CD55/FIS1/STOML2/ATP2B1/BNIP3/CAV1 15 GO:0015833 peptide transport 9/435 264/18722 0.163069122750581 0.621712200453875 FAM3B/EGFR/GJA1/SLC13A3/PARK7/MPC2/HMGN3/BAD/PHPT1 9 GO:0006289 nucleotide-excision repair 3/435 60/18722 0.163087506714966 0.621712200453875 GTF2H5/POLR2I/DDB1 3 GO:0031102 neuron projection regeneration 3/435 60/18722 0.163087506714966 0.621712200453875 FOLR1/DAG1/NREP 3 GO:0033866 nucleoside bisphosphate biosynthetic process 3/435 60/18722 0.163087506714966 0.621712200453875 ACSS1/TECR/MPC2 3 GO:0034030 ribonucleoside bisphosphate biosynthetic process 3/435 60/18722 0.163087506714966 0.621712200453875 ACSS1/TECR/MPC2 3 GO:0034033 purine nucleoside bisphosphate biosynthetic process 3/435 60/18722 0.163087506714966 0.621712200453875 ACSS1/TECR/MPC2 3 GO:0042306 regulation of protein import into nucleus 3/435 60/18722 0.163087506714966 0.621712200453875 CDH1/HSP90AB1/FERMT1 3 GO:0055008 cardiac muscle tissue morphogenesis 3/435 60/18722 0.163087506714966 0.621712200453875 DSP/LRP2/LY6E 3 GO:0061951 establishment of protein localization to plasma membrane 3/435 60/18722 0.163087506714966 0.621712200453875 KRT18/CLN3/NSG1 3 GO:0042063 gliogenesis 10/435 301/18722 0.16478645859305 0.627584231619536 SPINT1/GSTP1/SOD1/ADGRG1/EGFR/LRP2/APP/ITGB4/DAG1/BNIP3 10 GO:0002253 activation of immune response 12/435 375/18722 0.165495315933128 0.629677851103259 CD59/RPS3/SLC39A10/C1QBP/LGALS3/CD46/CD55/PHB/STOML2/KCNN4/PHPT1/CD47 12 GO:0072163 mesonephric epithelium development 4/435 92/18722 0.166130377453682 0.630880905551076 MAGED1/BMP7/LAMA5/TACSTD2 4 GO:0072164 mesonephric tubule development 4/435 92/18722 0.166130377453682 0.630880905551076 MAGED1/BMP7/LAMA5/TACSTD2 4 GO:0002697 regulation of immune effector process 11/435 339/18722 0.167745261463697 0.63640268419161 VAMP8/RPS19/CD59/HSPD1/C1QBP/LGALS3/CD46/CADM1/CD55/PHB/CD47 11 GO:0030073 insulin secretion 7/435 195/18722 0.169643462579411 0.640824485253302 FAM3B/GJA1/PARK7/MPC2/HMGN3/BAD/PHPT1 7 GO:0070302 regulation of stress-activated protein kinase signaling cascade 7/435 195/18722 0.169643462579411 0.640824485253302 PAGE4/GSTP1/EGFR/PRDX1/ARL6IP5/APP/PRMT1 7 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity 2/435 32/18722 0.169882457677714 0.640824485253302 CDKN1C/NR2F2 2 GO:0060914 heart formation 2/435 32/18722 0.169882457677714 0.640824485253302 FOLR1/LRP2 2 GO:0090140 regulation of mitochondrial fission 2/435 32/18722 0.169882457677714 0.640824485253302 FIS1/BNIP3 2 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 2/435 32/18722 0.169882457677714 0.640824485253302 ERP29/PARK7 2 GO:0051591 response to cAMP 4/435 93/18722 0.170649374033249 0.642492457706533 BSG/APP/CDO1/ASS1 4 GO:0060993 kidney morphogenesis 4/435 93/18722 0.170649374033249 0.642492457706533 MAGED1/BMP7/LAMA5/TACSTD2 4 GO:0043393 regulation of protein binding 7/435 196/18722 0.17268334721109 0.648549154736174 PHLDA2/ANXA2/LRPAP1/APP/HSP90AB1/PARK7/CAV1 7 GO:0036294 cellular response to decreased oxygen levels 6/435 161/18722 0.172811222137071 0.648549154736174 BMP7/P4HB/HILPDA/BAD/LMNA/BNIP3 6 GO:0010594 regulation of endothelial cell migration 8/435 232/18722 0.173692905688729 0.648549154736174 SERPINF1/NRP2/ANXA3/MET/EFNA1/NR2F2/CALR/PDCD6 8 GO:0007588 excretion 3/435 62/18722 0.174505846673888 0.648549154736174 COMT/CLN3/ATP6V1B1 3 GO:0032613 interleukin-10 production 3/435 62/18722 0.174505846673888 0.648549154736174 HSPD1/CD46/CD47 3 GO:0032615 interleukin-12 production 3/435 62/18722 0.174505846673888 0.648549154736174 HSPD1/C1QBP/CD47 3 GO:0032623 interleukin-2 production 3/435 62/18722 0.174505846673888 0.648549154736174 PNP/RPS3/STOML2 3 GO:0032653 regulation of interleukin-10 production 3/435 62/18722 0.174505846673888 0.648549154736174 HSPD1/CD46/CD47 3 GO:0032655 regulation of interleukin-12 production 3/435 62/18722 0.174505846673888 0.648549154736174 HSPD1/C1QBP/CD47 3 GO:0032663 regulation of interleukin-2 production 3/435 62/18722 0.174505846673888 0.648549154736174 PNP/RPS3/STOML2 3 GO:0060675 ureteric bud morphogenesis 3/435 62/18722 0.174505846673888 0.648549154736174 MAGED1/LAMA5/TACSTD2 3 GO:0070265 necrotic cell death 3/435 62/18722 0.174505846673888 0.648549154736174 HEBP2/BNIP3/CAV1 3 GO:1903078 positive regulation of protein localization to plasma membrane 3/435 62/18722 0.174505846673888 0.648549154736174 EGFR/CLN3/LGALS3 3 GO:0001933 negative regulation of protein phosphorylation 11/435 342/18722 0.174552653473345 0.648549154736174 GSTP1/CDKN1C/PKIB/MLLT1/FBLN1/BMP7/CTDSPL/NR2F2/PARK7/NPM1/CAV1 11 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 4/435 94/18722 0.175210967413469 0.649774881026333 EGFR/CDKN1C/NR2F2/CCND1 4 GO:1902414 protein localization to cell junction 4/435 94/18722 0.175210967413469 0.649774881026333 DSP/DAG1/NSG1/LSR 4 GO:0001881 receptor recycling 2/435 33/18722 0.178221711674526 0.652616659555686 ANXA2/NSG1 2 GO:0003382 epithelial cell morphogenesis 2/435 33/18722 0.178221711674526 0.652616659555686 SPINT2/MET 2 GO:0031116 positive regulation of microtubule polymerization 2/435 33/18722 0.178221711674526 0.652616659555686 MET/RPS3 2 GO:0036336 dendritic cell migration 2/435 33/18722 0.178221711674526 0.652616659555686 C1QBP/CALR 2 GO:0048333 mesodermal cell differentiation 2/435 33/18722 0.178221711674526 0.652616659555686 GJA1/ITGB4 2 GO:0071295 cellular response to vitamin 2/435 33/18722 0.178221711674526 0.652616659555686 FOLR1/ATP2B1 2 GO:0071353 cellular response to interleukin-4 2/435 33/18722 0.178221711674526 0.652616659555686 RPLP0/HSP90AB1 2 GO:1901099 negative regulation of signal transduction in absence of ligand 2/435 33/18722 0.178221711674526 0.652616659555686 IFI6/PRDX2 2 GO:1903146 regulation of autophagy of mitochondrion 2/435 33/18722 0.178221711674526 0.652616659555686 PARK7/BNIP3 2 GO:1904030 negative regulation of cyclin-dependent protein kinase activity 2/435 33/18722 0.178221711674526 0.652616659555686 CDKN1C/NR2F2 2 GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 2/435 33/18722 0.178221711674526 0.652616659555686 IFI6/PRDX2 2 GO:0050678 regulation of epithelial cell proliferation 12/435 381/18722 0.178425565349504 0.652616659555686 SERPINF1/MAGED1/EGFR/CDKN1C/NRP2/GJA1/NR2F2/MYDGF/BAD/CCND1/CAV1/PDCD6 12 GO:0030336 negative regulation of cell migration 11/435 344/18722 0.179163688926763 0.652616659555686 SERPINF1/GSTP1/ADGRG1/CDH1/GJA1/NR2F2/DAG1/CALR/MIF/TACSTD2/S1PR2 11 GO:0061025 membrane fusion 6/435 163/18722 0.179650099079051 0.652616659555686 CTSL/ANXA2/VAMP8/FOLR1/SPESP1/CLN3 6 GO:0006942 regulation of striated muscle contraction 4/435 95/18722 0.179813921011354 0.652616659555686 DSP/GJA5/DSC2/CAV1 4 GO:0032233 positive regulation of actin filament bundle assembly 3/435 63/18722 0.180297310322189 0.652616659555686 S100A10/RHOC/CD47 3 GO:0046902 regulation of mitochondrial membrane permeability 3/435 63/18722 0.180297310322189 0.652616659555686 HEBP2/BAD/BNIP3 3 GO:0072171 mesonephric tubule morphogenesis 3/435 63/18722 0.180297310322189 0.652616659555686 MAGED1/LAMA5/TACSTD2 3 GO:1902903 regulation of supramolecular fiber organization 12/435 382/18722 0.180626960585839 0.652616659555686 MET/APP/RPS3/S100A10/PARK7/DSTN/TACSTD2/KANK4/PFDN1/RHOC/WASF2/CD47 12 GO:0034329 cell junction assembly 13/435 420/18722 0.181416584516222 0.652616659555686 CLDN4/ITGA6/CDH1/APP/GJA1/ITGB4/GJA5/S100A10/CLDN7/CAV1/RHOC/LSR/RAB17 13 GO:0007498 mesoderm development 5/435 129/18722 0.181681901269394 0.652616659555686 MEST/BMP7/WLS/GJA1/ITGB4 5 GO:0042098 T cell proliferation 7/435 199/18722 0.181943025938887 0.652616659555686 CD24/PRDX2/PNP/RPS3/LGALS3/CD46/CD55 7 GO:0050680 negative regulation of epithelial cell proliferation 6/435 164/18722 0.183109928387941 0.652616659555686 SERPINF1/MAGED1/CDKN1C/GJA1/NR2F2/CAV1 6 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 6/435 164/18722 0.183109928387941 0.652616659555686 RPL23/RPS7/BCAP31/HSP90AB1/PARK7/CAV1 6 GO:0022604 regulation of cell morphogenesis 10/435 309/18722 0.184227864202243 0.652616659555686 CLDN4/FBLN1/P4HB/MYH10/S100A10/C1QBP/DAG1/CALR/TACSTD2/RHOC 10 GO:0001823 mesonephros development 4/435 96/18722 0.184456992691066 0.652616659555686 MAGED1/BMP7/LAMA5/TACSTD2 4 GO:0030072 peptide hormone secretion 8/435 236/18722 0.185053297040848 0.652616659555686 FAM3B/EGFR/GJA1/PARK7/MPC2/HMGN3/BAD/PHPT1 8 GO:0071902 positive regulation of protein serine/threonine kinase activity 7/435 200/18722 0.185075190200732 0.652616659555686 CD24/MAGED1/EGFR/HSP90AB1/RPS3/ERP29/CCND1 7 GO:0006956 complement activation 5/435 130/18722 0.185632764460648 0.652616659555686 CD59/C1QBP/CD46/CD55/PHB 5 GO:0006940 regulation of smooth muscle contraction 3/435 64/18722 0.186140175672454 0.652616659555686 SOD1/ATP2B1/CAV1 3 GO:0070542 response to fatty acid 3/435 64/18722 0.186140175672454 0.652616659555686 GLDC/BAD/ASS1 3 GO:0010639 negative regulation of organelle organization 11/435 347/18722 0.186187107437756 0.652616659555686 BMP7/MET/PARP1/AURKAIP1/LMNA/TACSTD2/NPM1/BNIP3/KANK4/WASF2/LCMT1 11 GO:0002183 cytoplasmic translational initiation 2/435 34/18722 0.1866223198061 0.652616659555686 EIF3G/EIF2S2 2 GO:0010922 positive regulation of phosphatase activity 2/435 34/18722 0.1866223198061 0.652616659555686 HSP90AB1/SLC39A10 2 GO:0034383 low-density lipoprotein particle clearance 2/435 34/18722 0.1866223198061 0.652616659555686 ANXA2/CNPY2 2 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus 2/435 34/18722 0.1866223198061 0.652616659555686 C1QBP/PHB 2 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 2/435 34/18722 0.1866223198061 0.652616659555686 MIF/NPM1 2 GO:0044319 wound healing, spreading of cells 2/435 34/18722 0.1866223198061 0.652616659555686 FERMT1/RHOC 2 GO:0051973 positive regulation of telomerase activity 2/435 34/18722 0.1866223198061 0.652616659555686 PKIB/HSP90AB1 2 GO:0070232 regulation of T cell apoptotic process 2/435 34/18722 0.1866223198061 0.652616659555686 EFNA1/LGALS3 2 GO:0086019 cell-cell signaling involved in cardiac conduction 2/435 34/18722 0.1866223198061 0.652616659555686 GJA1/GJA5 2 GO:0090505 epiboly involved in wound healing 2/435 34/18722 0.1866223198061 0.652616659555686 FERMT1/RHOC 2 GO:1990000 amyloid fibril formation 2/435 34/18722 0.1866223198061 0.652616659555686 APP/PFDN1 2 GO:0051047 positive regulation of secretion 10/435 310/18722 0.186729202209195 0.652616659555686 EGFR/VAMP8/WLS/GJA1/SLC6A4/MYH10/MPC2/BAD/KCNN4/PHPT1 10 GO:0070167 regulation of biomineral tissue development 4/435 97/18722 0.189138935820849 0.652616659555686 FBN2/BMP7/ATRAID/ATP2B1 4 GO:0120162 positive regulation of cold-induced thermogenesis 4/435 97/18722 0.189138935820849 0.652616659555686 GNAS/GJA1/ADRB1/CAV1 4 GO:0050727 regulation of inflammatory response 12/435 386/18722 0.189561460150196 0.652616659555686 SERPINF1/GSTP1/SOD1/EGFR/VAMP8/TGM2/RPS19/HSPD1/APP/PARK7/CD47/LPCAT3 12 GO:0019079 viral genome replication 5/435 131/18722 0.189614774578647 0.652616659555686 PPIB/HACD3/PHB/LAMTOR5/DDB1 5 GO:0038034 signal transduction in absence of ligand 3/435 65/18722 0.192031873160976 0.652616659555686 IFI6/PRDX2/BAD 3 GO:0048524 positive regulation of viral process 3/435 65/18722 0.192031873160976 0.652616659555686 P4HB/HACD3/DDB1 3 GO:0048645 animal organ formation 3/435 65/18722 0.192031873160976 0.652616659555686 FOLR1/BMP7/LRP2 3 GO:0070613 regulation of protein processing 3/435 65/18722 0.192031873160976 0.652616659555686 CLN3/TMEM59/LPCAT3 3 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 3/435 65/18722 0.192031873160976 0.652616659555686 IFI6/PRDX2/BAD 3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 6/435 167/18722 0.193645343946471 0.652616659555686 BSG/CDH1/DSC2/TENM3/CADM1/DSC3 6 GO:0003333 amino acid transmembrane transport 4/435 98/18722 0.193858500299168 0.652616659555686 ARL6IP5/SLC43A2/SLC38A9/SLC1A5 4 GO:0070301 cellular response to hydrogen peroxide 4/435 98/18722 0.193858500299168 0.652616659555686 MET/RPS3/PARK7/BNIP3 4 GO:0007548 sex differentiation 9/435 276/18722 0.194579791596635 0.652616659555686 SOD1/ADGRG1/LRP2/PRDX4/IDH1/NR2F2/EIF2S2/DNAJC19/CCND1 9 GO:0006643 membrane lipid metabolic process 7/435 203/18722 0.194603873868549 0.652616659555686 DEGS1/SERINC2/HACD3/FUCA1/TECR/PYURF/ORMDL1 7 GO:0006084 acetyl-CoA metabolic process 2/435 35/18722 0.195076951929492 0.652616659555686 ACSS1/MPC2 2 GO:0018149 peptide cross-linking 2/435 35/18722 0.195076951929492 0.652616659555686 DSP/TGM2 2 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 2/435 35/18722 0.195076951929492 0.652616659555686 HSP90AB1/PARK7 2 GO:0033146 regulation of intracellular estrogen receptor signaling pathway 2/435 35/18722 0.195076951929492 0.652616659555686 PARP1/SKP2 2 GO:0033280 response to vitamin D 2/435 35/18722 0.195076951929492 0.652616659555686 BMP7/ATP2B1 2 GO:0034405 response to fluid shear stress 2/435 35/18722 0.195076951929492 0.652616659555686 GJA1/ASS1 2 GO:0035633 maintenance of blood-brain barrier 2/435 35/18722 0.195076951929492 0.652616659555686 GJA1/LSR 2 GO:0043243 positive regulation of protein-containing complex disassembly 2/435 35/18722 0.195076951929492 0.652616659555686 DSTN/BNIP3 2 GO:0090504 epiboly 2/435 35/18722 0.195076951929492 0.652616659555686 FERMT1/RHOC 2 GO:0098810 neurotransmitter reuptake 2/435 35/18722 0.195076951929492 0.652616659555686 SLC6A4/PARK7 2 GO:1905898 positive regulation of response to endoplasmic reticulum stress 2/435 35/18722 0.195076951929492 0.652616659555686 BCAP31/CAV1 2 GO:0070085 glycosylation 8/435 240/18722 0.196724157509721 0.652616659555686 GALNT11/TUSC3/EXTL2/DDOST/RPN2/OSTC/TMEM59/TMEM258 8 GO:0010565 regulation of cellular ketone metabolic process 5/435 133/18722 0.197669302533768 0.652616659555686 COMT/CLN3/PARK7/ACADVL/CAV1 5 GO:0010595 positive regulation of endothelial cell migration 5/435 133/18722 0.197669302533768 0.652616659555686 NRP2/ANXA3/MET/CALR/PDCD6 5 GO:0030193 regulation of blood coagulation 3/435 66/18722 0.197969856468097 0.652616659555686 ANXA2/PRDX2/CAV1 3 GO:0050766 positive regulation of phagocytosis 3/435 66/18722 0.197969856468097 0.652616659555686 SOD1/CALR/CD47 3 GO:0050918 positive chemotaxis 3/435 66/18722 0.197969856468097 0.652616659555686 MET/LGALS3/MIF 3 GO:0071300 cellular response to retinoic acid 3/435 66/18722 0.197969856468097 0.652616659555686 SERPINF1/NDUFA13/SLC6A4 3 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 4/435 99/18722 0.19861443355015 0.652616659555686 RPS3/BAD/MIF/SHISA5 4 GO:0031341 regulation of cell killing 4/435 99/18722 0.19861443355015 0.652616659555686 CD59/HSP90AB1/CADM1/CD55 4 GO:0110149 regulation of biomineralization 4/435 99/18722 0.19861443355015 0.652616659555686 FBN2/BMP7/ATRAID/ATP2B1 4 GO:0060047 heart contraction 8/435 241/18722 0.199688508084151 0.652616659555686 SOD1/DSP/GJA1/ADRB1/GJA5/DSC2/ATP2B1/CAV1 8 GO:0006937 regulation of muscle contraction 6/435 169/18722 0.200794092303216 0.652616659555686 SOD1/DSP/GJA5/DSC2/ATP2B1/CAV1 6 GO:0021543 pallium development 6/435 169/18722 0.200794092303216 0.652616659555686 ADGRG1/SLC2A1/UQCRQ/ANXA3/BAD/BNIP3 6 GO:0042552 myelination 5/435 134/18722 0.201740340844102 0.652616659555686 SOD1/DEGS1/ITGB4/DAG1/CMTM8 5 GO:0002790 peptide secretion 8/435 242/18722 0.202670996185872 0.652616659555686 FAM3B/EGFR/GJA1/PARK7/MPC2/HMGN3/BAD/PHPT1 8 GO:0043542 endothelial cell migration 9/435 279/18722 0.20284173642488 0.652616659555686 SERPINF1/NRP2/ANXA3/MET/EFNA1/NR2F2/CALR/AMOT/PDCD6 9 GO:0046486 glycerolipid metabolic process 12/435 392/18722 0.203338614969443 0.652616659555686 TMEM150A/CLN3/SERINC2/PRDX6/PISD/DBI/PYURF/STOML2/DNAJC19/HADHA/CAV1/LPCAT3 12 GO:0060840 artery development 4/435 100/18722 0.203405481488456 0.652616659555686 FOLR1/LRP2/GJA5/ADAMTS6 4 GO:0009225 nucleotide-sugar metabolic process 2/435 36/18722 0.203578583950044 0.652616659555686 EXTL2/UGP2 2 GO:0017004 cytochrome complex assembly 2/435 36/18722 0.203578583950044 0.652616659555686 COA4/COX20 2 GO:0051955 regulation of amino acid transport 2/435 36/18722 0.203578583950044 0.652616659555686 ARL6IP5/SLC43A2 2 GO:0070670 response to interleukin-4 2/435 36/18722 0.203578583950044 0.652616659555686 RPLP0/HSP90AB1 2 GO:1901658 glycosyl compound catabolic process 2/435 36/18722 0.203578583950044 0.652616659555686 PNP/FUCA1 2 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 2/435 36/18722 0.203578583950044 0.652616659555686 RPS3/MIF 2 GO:1903539 protein localization to postsynaptic membrane 2/435 36/18722 0.203578583950044 0.652616659555686 DAG1/NSG1 2 GO:0032890 regulation of organic acid transport 3/435 67/18722 0.203951604392752 0.652616659555686 ARL6IP5/SLC43A2/FIS1 3 GO:1903317 regulation of protein maturation 3/435 67/18722 0.203951604392752 0.652616659555686 CLN3/TMEM59/LPCAT3 3 GO:0008016 regulation of heart contraction 7/435 206/18722 0.20432368673823 0.652616659555686 DSP/GJA1/ADRB1/GJA5/DSC2/ATP2B1/CAV1 7 GO:0048863 stem cell differentiation 7/435 206/18722 0.20432368673823 0.652616659555686 KRT18/NRP2/FOLR1/BMP7/LAMA5/TACSTD2/PDCD6 7 GO:0002687 positive regulation of leukocyte migration 5/435 135/18722 0.205839567983047 0.652616659555686 APP/C1QBP/LGALS3/CALR/CD47 5 GO:0042129 regulation of T cell proliferation 6/435 171/18722 0.208038381001899 0.652616659555686 CD24/PNP/RPS3/LGALS3/CD46/CD55 6 GO:0048024 regulation of mRNA splicing, via spliceosome 4/435 101/18722 0.208230389453744 0.652616659555686 MBNL3/PRDX6/C1QBP/NPM1 4 GO:0000050 urea cycle 1/435 10/18722 0.20954454573939 0.652616659555686 ASS1 1 GO:0000098 sulfur amino acid catabolic process 1/435 10/18722 0.20954454573939 0.652616659555686 CDO1 1 GO:0000255 allantoin metabolic process 1/435 10/18722 0.20954454573939 0.652616659555686 PNP 1 GO:0001820 serotonin secretion 1/435 10/18722 0.20954454573939 0.652616659555686 SLC6A4 1 GO:0002002 regulation of angiotensin levels in blood 1/435 10/18722 0.20954454573939 0.652616659555686 MME 1 GO:0002003 angiotensin maturation 1/435 10/18722 0.20954454573939 0.652616659555686 MME 1 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 1/435 10/18722 0.20954454573939 0.652616659555686 LGALS3 1 GO:0003056 regulation of vascular associated smooth muscle contraction 1/435 10/18722 0.20954454573939 0.652616659555686 ATP2B1 1 GO:0003183 mitral valve morphogenesis 1/435 10/18722 0.20954454573939 0.652616659555686 EFNA1 1 GO:0006283 transcription-coupled nucleotide-excision repair 1/435 10/18722 0.20954454573939 0.652616659555686 POLR2I 1 GO:0006646 phosphatidylethanolamine biosynthetic process 1/435 10/18722 0.20954454573939 0.652616659555686 PISD 1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway 1/435 10/18722 0.20954454573939 0.652616659555686 GNAS 1 GO:0009169 purine ribonucleoside monophosphate catabolic process 1/435 10/18722 0.20954454573939 0.652616659555686 PNP 1 GO:0009170 purine deoxyribonucleoside monophosphate metabolic process 1/435 10/18722 0.20954454573939 0.652616659555686 PNP 1 GO:0009750 response to fructose 1/435 10/18722 0.20954454573939 0.652616659555686 KRT18 1 GO:0010172 embryonic body morphogenesis 1/435 10/18722 0.20954454573939 0.652616659555686 DAG1 1 GO:0010944 negative regulation of transcription by competitive promoter binding 1/435 10/18722 0.20954454573939 0.652616659555686 PHB 1 GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation 1/435 10/18722 0.20954454573939 0.652616659555686 NPM1 1 GO:0015911 long-chain fatty acid import across plasma membrane 1/435 10/18722 0.20954454573939 0.652616659555686 SLC2A1 1 GO:0016139 glycoside catabolic process 1/435 10/18722 0.20954454573939 0.652616659555686 FUCA1 1 GO:0016559 peroxisome fission 1/435 10/18722 0.20954454573939 0.652616659555686 FIS1 1 GO:0019062 virion attachment to host cell 1/435 10/18722 0.20954454573939 0.652616659555686 HSP90AB1 1 GO:0019614 catechol-containing compound catabolic process 1/435 10/18722 0.20954454573939 0.652616659555686 COMT 1 GO:0021548 pons development 1/435 10/18722 0.20954454573939 0.652616659555686 UQCRQ 1 GO:0021562 vestibulocochlear nerve development 1/435 10/18722 0.20954454573939 0.652616659555686 NRP2 1 GO:0030300 regulation of intestinal cholesterol absorption 1/435 10/18722 0.20954454573939 0.652616659555686 LPCAT3 1 GO:0030638 polyketide metabolic process 1/435 10/18722 0.20954454573939 0.652616659555686 AKR1B1 1 GO:0030647 aminoglycoside antibiotic metabolic process 1/435 10/18722 0.20954454573939 0.652616659555686 AKR1B1 1 GO:0031118 rRNA pseudouridine synthesis 1/435 10/18722 0.20954454573939 0.652616659555686 NHP2 1 GO:0031125 rRNA 3'-end processing 1/435 10/18722 0.20954454573939 0.652616659555686 RPS21 1 GO:0031340 positive regulation of vesicle fusion 1/435 10/18722 0.20954454573939 0.652616659555686 ANXA2 1 GO:0032380 regulation of intracellular sterol transport 1/435 10/18722 0.20954454573939 0.652616659555686 ANXA2 1 GO:0032383 regulation of intracellular cholesterol transport 1/435 10/18722 0.20954454573939 0.652616659555686 ANXA2 1 GO:0033131 regulation of glucokinase activity 1/435 10/18722 0.20954454573939 0.652616659555686 BAD 1 GO:0036152 phosphatidylethanolamine acyl-chain remodeling 1/435 10/18722 0.20954454573939 0.652616659555686 LPCAT3 1 GO:0036363 transforming growth factor beta activation 1/435 10/18722 0.20954454573939 0.652616659555686 HSP90AB1 1 GO:0040015 negative regulation of multicellular organism growth 1/435 10/18722 0.20954454573939 0.652616659555686 ADRB1 1 GO:0042424 catecholamine catabolic process 1/435 10/18722 0.20954454573939 0.652616659555686 COMT 1 GO:0042996 regulation of Golgi to plasma membrane protein transport 1/435 10/18722 0.20954454573939 0.652616659555686 CLN3 1 GO:0043101 purine-containing compound salvage 1/435 10/18722 0.20954454573939 0.652616659555686 PNP 1 GO:0044557 relaxation of smooth muscle 1/435 10/18722 0.20954454573939 0.652616659555686 SOD1 1 GO:0044598 doxorubicin metabolic process 1/435 10/18722 0.20954454573939 0.652616659555686 AKR1B1 1 GO:0044848 biological phase 1/435 10/18722 0.20954454573939 0.652616659555686 FERMT1 1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence 1/435 10/18722 0.20954454573939 0.652616659555686 EMC7 1 GO:0048194 Golgi vesicle budding 1/435 10/18722 0.20954454573939 0.652616659555686 TMED9 1 GO:0048241 epinephrine transport 1/435 10/18722 0.20954454573939 0.652616659555686 LY6E 1 GO:0050861 positive regulation of B cell receptor signaling pathway 1/435 10/18722 0.20954454573939 0.652616659555686 SLC39A10 1 GO:0060068 vagina development 1/435 10/18722 0.20954454573939 0.652616659555686 LRP2 1 GO:0060272 embryonic skeletal joint morphogenesis 1/435 10/18722 0.20954454573939 0.652616659555686 BMP7 1 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway 1/435 10/18722 0.20954454573939 0.652616659555686 CD47 1 GO:0060513 prostatic bud formation 1/435 10/18722 0.20954454573939 0.652616659555686 BMP7 1 GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 1/435 10/18722 0.20954454573939 0.652616659555686 SERPINF1 1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum 1/435 10/18722 0.20954454573939 0.652616659555686 ERLEC1 1 GO:0072124 regulation of glomerular mesangial cell proliferation 1/435 10/18722 0.20954454573939 0.652616659555686 BMP7 1 GO:0072203 cell proliferation involved in metanephros development 1/435 10/18722 0.20954454573939 0.652616659555686 BMP7 1 GO:0072378 blood coagulation, fibrin clot formation 1/435 10/18722 0.20954454573939 0.652616659555686 FBLN1 1 GO:0090043 regulation of tubulin deacetylation 1/435 10/18722 0.20954454573939 0.652616659555686 BEX4 1 GO:0090647 modulation of age-related behavioral decline 1/435 10/18722 0.20954454573939 0.652616659555686 APP 1 GO:0097250 mitochondrial respirasome assembly 1/435 10/18722 0.20954454573939 0.652616659555686 COX7A2 1 GO:0098885 modification of postsynaptic actin cytoskeleton 1/435 10/18722 0.20954454573939 0.652616659555686 MYH10 1 GO:0098903 regulation of membrane repolarization during action potential 1/435 10/18722 0.20954454573939 0.652616659555686 CAV1 1 GO:0098917 retrograde trans-synaptic signaling 1/435 10/18722 0.20954454573939 0.652616659555686 DAG1 1 GO:0099639 neurotransmitter receptor transport, endosome to plasma membrane 1/435 10/18722 0.20954454573939 0.652616659555686 NSG1 1 GO:1901203 positive regulation of extracellular matrix assembly 1/435 10/18722 0.20954454573939 0.652616659555686 DAG1 1 GO:1902023 L-arginine transport 1/435 10/18722 0.20954454573939 0.652616659555686 SLC38A9 1 GO:1902959 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 1/435 10/18722 0.20954454573939 0.652616659555686 EFNA1 1 GO:1903826 arginine transmembrane transport 1/435 10/18722 0.20954454573939 0.652616659555686 SLC38A9 1 GO:1903867 extraembryonic membrane development 1/435 10/18722 0.20954454573939 0.652616659555686 BMP7 1 GO:1904350 regulation of protein catabolic process in the vacuole 1/435 10/18722 0.20954454573939 0.652616659555686 LRP2 1 GO:1990535 neuron projection maintenance 1/435 10/18722 0.20954454573939 0.652616659555686 APP 1 GO:2000121 regulation of removal of superoxide radicals 1/435 10/18722 0.20954454573939 0.652616659555686 BMP7 1 GO:2000234 positive regulation of rRNA processing 1/435 10/18722 0.20954454573939 0.652616659555686 TRMT112 1 GO:2000425 regulation of apoptotic cell clearance 1/435 10/18722 0.20954454573939 0.652616659555686 TGM2 1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation 1/435 10/18722 0.20954454573939 0.652616659555686 WASF2 1 GO:2001223 negative regulation of neuron migration 1/435 10/18722 0.20954454573939 0.652616659555686 ADGRG1 1 GO:0003158 endothelium development 5/435 136/18722 0.209966233327349 0.652616659555686 MET/GJA1/GJA5/NR2F2/S1PR2 5 GO:0007272 ensheathment of neurons 5/435 136/18722 0.209966233327349 0.652616659555686 SOD1/DEGS1/ITGB4/DAG1/CMTM8 5 GO:0008366 axon ensheathment 5/435 136/18722 0.209966233327349 0.652616659555686 SOD1/DEGS1/ITGB4/DAG1/CMTM8 5 GO:0072073 kidney epithelium development 5/435 136/18722 0.209966233327349 0.652616659555686 CD24/MAGED1/BMP7/LAMA5/TACSTD2 5 GO:0098876 vesicle-mediated transport to the plasma membrane 5/435 136/18722 0.209966233327349 0.652616659555686 KRT18/CLN3/NSG1/SNX3/RAB17 5 GO:0007585 respiratory gaseous exchange by respiratory system 3/435 68/18722 0.209974622591938 0.652616659555686 COX5B/ADH5/NDUFA12 3 GO:0009988 cell-cell recognition 3/435 68/18722 0.209974622591938 0.652616659555686 FOLR1/SPESP1/LGALS3 3 GO:0046686 response to cadmium ion 3/435 68/18722 0.209974622591938 0.652616659555686 SOD1/EGFR/CYB5A 3 GO:0060411 cardiac septum morphogenesis 3/435 68/18722 0.209974622591938 0.652616659555686 NRP2/BMP7/LRP2 3 GO:1900046 regulation of hemostasis 3/435 68/18722 0.209974622591938 0.652616659555686 ANXA2/PRDX2/CAV1 3 GO:0010631 epithelial cell migration 11/435 357/18722 0.210484440268266 0.652616659555686 SERPINF1/NRP2/ANXA3/MET/EFNA1/NR2F2/CALR/FERMT1/AMOT/TACSTD2/PDCD6 11 GO:0001678 cellular glucose homeostasis 6/435 172/18722 0.211695107503448 0.652616659555686 SERPINF1/MPC2/HMGN3/BAD/FIS1/PHPT1 6 GO:0048736 appendage development 6/435 172/18722 0.211695107503448 0.652616659555686 ITGA6/FBN2/BMP7/SLC39A1/ITGB4/NR2F2 6 GO:0060173 limb development 6/435 172/18722 0.211695107503448 0.652616659555686 ITGA6/FBN2/BMP7/SLC39A1/ITGB4/NR2F2 6 GO:0000154 rRNA modification 2/435 37/18722 0.212120487611701 0.652616659555686 NHP2/TRMT112 2 GO:0031112 positive regulation of microtubule polymerization or depolymerization 2/435 37/18722 0.212120487611701 0.652616659555686 MET/RPS3 2 GO:0042401 cellular biogenic amine biosynthetic process 2/435 37/18722 0.212120487611701 0.652616659555686 SMS/PARK7 2 GO:0051567 histone H3-K9 methylation 2/435 37/18722 0.212120487611701 0.652616659555686 DNMT1/LMNA 2 GO:0060306 regulation of membrane repolarization 2/435 37/18722 0.212120487611701 0.652616659555686 GJA5/CAV1 2 GO:0062237 protein localization to postsynapse 2/435 37/18722 0.212120487611701 0.652616659555686 DAG1/NSG1 2 GO:1905332 positive regulation of morphogenesis of an epithelium 2/435 37/18722 0.212120487611701 0.652616659555686 MAGED1/GJA1 2 GO:0034308 primary alcohol metabolic process 4/435 102/18722 0.213087903114942 0.652616659555686 ACSS1/ADH5/PARK7/AKR1B1 4 GO:0044262 cellular carbohydrate metabolic process 9/435 283/18722 0.214079284153465 0.652616659555686 PHLDA2/ISYNA1/UGP2/IDH1/AGL/AKR1B1/BAD/DDB1/LCMT1 9 GO:0006986 response to unfolded protein 5/435 137/18722 0.214119582742678 0.652616659555686 HSPD1/HSPE1/HSP90AB1/CCND1/ERLEC1 5 GO:0008203 cholesterol metabolic process 5/435 137/18722 0.214119582742678 0.652616659555686 SOD1/APP/ACADVL/FDFT1/LPCAT3 5 GO:0060048 cardiac muscle contraction 5/435 137/18722 0.214119582742678 0.652616659555686 DSP/GJA1/GJA5/DSC2/CAV1 5 GO:0003007 heart morphogenesis 8/435 246/18722 0.214777005291125 0.652616659555686 NRP2/FOLR1/BMP7/DSP/LRP2/GJA5/EFNA1/LY6E 8 GO:1901653 cellular response to peptide 11/435 359/18722 0.215499560394724 0.652616659555686 GSTP1/RPL23/PARP1/APP/GJA1/FBN1/AKR1B1/ASS1/FIS1/ATP2B1/CAV1 11 GO:0007004 telomere maintenance via telomerase 3/435 69/18722 0.216036445191151 0.652616659555686 PKIB/HSP90AB1/NHP2 3 GO:0045669 positive regulation of osteoblast differentiation 3/435 69/18722 0.216036445191151 0.652616659555686 FBN2/BMP7/ATRAID 3 GO:0060193 positive regulation of lipase activity 3/435 69/18722 0.216036445191151 0.652616659555686 EGFR/PHB/RHOC 3 GO:1904377 positive regulation of protein localization to cell periphery 3/435 69/18722 0.216036445191151 0.652616659555686 EGFR/CLN3/LGALS3 3 GO:0007623 circadian rhythm 7/435 210/18722 0.217564356443304 0.652616659555686 CLDN4/MAGED1/EGFR/ADRB1/SLC6A4/ASS1/DDB1 7 GO:0002027 regulation of heart rate 4/435 103/18722 0.217976769344543 0.652616659555686 DSP/ADRB1/DSC2/CAV1 4 GO:0014013 regulation of gliogenesis 4/435 103/18722 0.217976769344543 0.652616659555686 SPINT1/EGFR/LRP2/DAG1 4 GO:0030593 neutrophil chemotaxis 4/435 103/18722 0.217976769344543 0.652616659555686 BSG/PPIB/C1QBP/LGALS3 4 GO:0090132 epithelium migration 11/435 360/18722 0.218025675226639 0.652616659555686 SERPINF1/NRP2/ANXA3/MET/EFNA1/NR2F2/CALR/FERMT1/AMOT/TACSTD2/PDCD6 11 GO:0048562 embryonic organ morphogenesis 9/435 285/18722 0.219789247773055 0.652616659555686 EFEMP1/SOD1/FBN2/FOLR1/BMP7/SLC39A1/FBN1/EFNA1/ATP6V1B1 9 GO:0008210 estrogen metabolic process 2/435 38/18722 0.220696220594791 0.652616659555686 COMT/HSD17B1 2 GO:0009309 amine biosynthetic process 2/435 38/18722 0.220696220594791 0.652616659555686 SMS/PARK7 2 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway 2/435 38/18722 0.220696220594791 0.652616659555686 CALR/PHB 2 GO:0042596 fear response 2/435 38/18722 0.220696220594791 0.652616659555686 GJA1/ADRB1 2 GO:0048246 macrophage chemotaxis 2/435 38/18722 0.220696220594791 0.652616659555686 LGALS3/MIF 2 GO:0072524 pyridine-containing compound metabolic process 2/435 38/18722 0.220696220594791 0.652616659555686 QPRT/PNP 2 GO:0042180 cellular ketone metabolic process 7/435 211/18722 0.220922283191323 0.652616659555686 COMT/HSD17B1/CLN3/PARK7/AKR1B1/ACADVL/CAV1 7 GO:0060415 muscle tissue morphogenesis 3/435 70/18722 0.222134636271645 0.652616659555686 DSP/LRP2/LY6E 3 GO:0070830 bicellular tight junction assembly 3/435 70/18722 0.222134636271645 0.652616659555686 CLDN4/GJA1/CLDN7 3 GO:0051251 positive regulation of lymphocyte activation 11/435 362/18722 0.223114289980303 0.652616659555686 CD24/HSPD1/PNP/RPS3/SLC39A10/BAD/CD46/MIF/CD55/CAV1/CD47 11 GO:0043523 regulation of neuron apoptotic process 7/435 212/18722 0.224298578409357 0.652616659555686 SOD1/PARP1/HSPD1/CLN3/HSP90AB1/PARK7/FIS1 7 GO:0015748 organophosphate ester transport 5/435 140/18722 0.226732150803667 0.652616659555686 GJA1/DBI/KCNN4/SLC19A1/CD47 5 GO:0001731 formation of translation preinitiation complex 1/435 11/18722 0.227920353916141 0.652616659555686 EIF2S2 1 GO:0001967 suckling behavior 1/435 11/18722 0.227920353916141 0.652616659555686 APP 1 GO:0002357 defense response to tumor cell 1/435 11/18722 0.227920353916141 0.652616659555686 PRDX2 1 GO:0003139 secondary heart field specification 1/435 11/18722 0.227920353916141 0.652616659555686 LRP2 1 GO:0006020 inositol metabolic process 1/435 11/18722 0.227920353916141 0.652616659555686 ISYNA1 1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate 1/435 11/18722 0.227920353916141 0.652616659555686 MPC2 1 GO:0007042 lysosomal lumen acidification 1/435 11/18722 0.227920353916141 0.652616659555686 CLN3 1 GO:0009120 deoxyribonucleoside metabolic process 1/435 11/18722 0.227920353916141 0.652616659555686 PNP 1 GO:0009128 purine nucleoside monophosphate catabolic process 1/435 11/18722 0.227920353916141 0.652616659555686 PNP 1 GO:0009155 purine deoxyribonucleotide catabolic process 1/435 11/18722 0.227920353916141 0.652616659555686 PNP 1 GO:0010739 positive regulation of protein kinase A signaling 1/435 11/18722 0.227920353916141 0.652616659555686 MIF 1 GO:0010986 positive regulation of lipoprotein particle clearance 1/435 11/18722 0.227920353916141 0.652616659555686 ANXA2 1 GO:0014854 response to inactivity 1/435 11/18722 0.227920353916141 0.652616659555686 DAG1 1 GO:0019048 modulation by virus of host process 1/435 11/18722 0.227920353916141 0.652616659555686 DAG1 1 GO:0021561 facial nerve development 1/435 11/18722 0.227920353916141 0.652616659555686 NRP2 1 GO:0021604 cranial nerve structural organization 1/435 11/18722 0.227920353916141 0.652616659555686 NRP2 1 GO:0021610 facial nerve morphogenesis 1/435 11/18722 0.227920353916141 0.652616659555686 NRP2 1 GO:0021860 pyramidal neuron development 1/435 11/18722 0.227920353916141 0.652616659555686 UQCRQ 1 GO:0032276 regulation of gonadotropin secretion 1/435 11/18722 0.227920353916141 0.652616659555686 GJA1 1 GO:0032329 serine transport 1/435 11/18722 0.227920353916141 0.652616659555686 SLC1A5 1 GO:0032377 regulation of intracellular lipid transport 1/435 11/18722 0.227920353916141 0.652616659555686 ANXA2 1 GO:0032610 interleukin-1 alpha production 1/435 11/18722 0.227920353916141 0.652616659555686 S100A13 1 GO:0032650 regulation of interleukin-1 alpha production 1/435 11/18722 0.227920353916141 0.652616659555686 S100A13 1 GO:0033197 response to vitamin E 1/435 11/18722 0.227920353916141 0.652616659555686 CCND1 1 GO:0033234 negative regulation of protein sumoylation 1/435 11/18722 0.227920353916141 0.652616659555686 PARK7 1 GO:0033327 Leydig cell differentiation 1/435 11/18722 0.227920353916141 0.652616659555686 CCND1 1 GO:0033625 positive regulation of integrin activation 1/435 11/18722 0.227920353916141 0.652616659555686 FERMT1 1 GO:0033860 regulation of NAD(P)H oxidase activity 1/435 11/18722 0.227920353916141 0.652616659555686 PARK7 1 GO:0034379 very-low-density lipoprotein particle assembly 1/435 11/18722 0.227920353916141 0.652616659555686 LPCAT3 1 GO:0034969 histone arginine methylation 1/435 11/18722 0.227920353916141 0.652616659555686 PRMT1 1 GO:0035246 peptidyl-arginine N-methylation 1/435 11/18722 0.227920353916141 0.652616659555686 PRMT1 1 GO:0035865 cellular response to potassium ion 1/435 11/18722 0.227920353916141 0.652616659555686 SOD1 1 GO:0039530 MDA-5 signaling pathway 1/435 11/18722 0.227920353916141 0.652616659555686 C1QBP 1 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 1/435 11/18722 0.227920353916141 0.652616659555686 C1QBP 1 GO:0042135 neurotransmitter catabolic process 1/435 11/18722 0.227920353916141 0.652616659555686 COMT 1 GO:0042416 dopamine biosynthetic process 1/435 11/18722 0.227920353916141 0.652616659555686 PARK7 1 GO:0042451 purine nucleoside biosynthetic process 1/435 11/18722 0.227920353916141 0.652616659555686 PNP 1 GO:0042455 ribonucleoside biosynthetic process 1/435 11/18722 0.227920353916141 0.652616659555686 PNP 1 GO:0043312 neutrophil degranulation 1/435 11/18722 0.227920353916141 0.652616659555686 ANXA3 1 GO:0045793 positive regulation of cell size 1/435 11/18722 0.227920353916141 0.652616659555686 HSP90AB1 1 GO:0046129 purine ribonucleoside biosynthetic process 1/435 11/18722 0.227920353916141 0.652616659555686 PNP 1 GO:0046598 positive regulation of viral entry into host cell 1/435 11/18722 0.227920353916141 0.652616659555686 P4HB 1 GO:0048102 autophagic cell death 1/435 11/18722 0.227920353916141 0.652616659555686 BNIP3 1 GO:0051573 negative regulation of histone H3-K9 methylation 1/435 11/18722 0.227920353916141 0.652616659555686 DNMT1 1 GO:0051574 positive regulation of histone H3-K9 methylation 1/435 11/18722 0.227920353916141 0.652616659555686 LMNA 1 GO:0051610 serotonin uptake 1/435 11/18722 0.227920353916141 0.652616659555686 SLC6A4 1 GO:0055015 ventricular cardiac muscle cell development 1/435 11/18722 0.227920353916141 0.652616659555686 LMNA 1 GO:0060767 epithelial cell proliferation involved in prostate gland development 1/435 11/18722 0.227920353916141 0.652616659555686 SERPINF1 1 GO:0061314 Notch signaling involved in heart development 1/435 11/18722 0.227920353916141 0.652616659555686 GALNT11 1 GO:0061635 regulation of protein complex stability 1/435 11/18722 0.227920353916141 0.652616659555686 SCOC 1 GO:0070243 regulation of thymocyte apoptotic process 1/435 11/18722 0.227920353916141 0.652616659555686 EFNA1 1 GO:0070475 rRNA base methylation 1/435 11/18722 0.227920353916141 0.652616659555686 TRMT112 1 GO:0070778 L-aspartate transmembrane transport 1/435 11/18722 0.227920353916141 0.652616659555686 SLC1A5 1 GO:0071377 cellular response to glucagon stimulus 1/435 11/18722 0.227920353916141 0.652616659555686 ASS1 1 GO:0071492 cellular response to UV-A 1/435 11/18722 0.227920353916141 0.652616659555686 MME 1 GO:0071679 commissural neuron axon guidance 1/435 11/18722 0.227920353916141 0.652616659555686 DAG1 1 GO:0071888 macrophage apoptotic process 1/435 11/18722 0.227920353916141 0.652616659555686 CTSL 1 GO:0072110 glomerular mesangial cell proliferation 1/435 11/18722 0.227920353916141 0.652616659555686 BMP7 1 GO:0072205 metanephric collecting duct development 1/435 11/18722 0.227920353916141 0.652616659555686 AKR1B1 1 GO:0072497 mesenchymal stem cell differentiation 1/435 11/18722 0.227920353916141 0.652616659555686 KRT18 1 GO:0075294 positive regulation by symbiont of entry into host 1/435 11/18722 0.227920353916141 0.652616659555686 P4HB 1 GO:0086016 AV node cell action potential 1/435 11/18722 0.227920353916141 0.652616659555686 GJA5 1 GO:0086027 AV node cell to bundle of His cell signaling 1/435 11/18722 0.227920353916141 0.652616659555686 GJA5 1 GO:0086070 SA node cell to atrial cardiac muscle cell communication 1/435 11/18722 0.227920353916141 0.652616659555686 GJA5 1 GO:0090160 Golgi to lysosome transport 1/435 11/18722 0.227920353916141 0.652616659555686 CLN3 1 GO:0090309 positive regulation of DNA methylation-dependent heterochromatin assembly 1/435 11/18722 0.227920353916141 0.652616659555686 DNMT1 1 GO:0090394 negative regulation of excitatory postsynaptic potential 1/435 11/18722 0.227920353916141 0.652616659555686 S1PR2 1 GO:0090649 response to oxygen-glucose deprivation 1/435 11/18722 0.227920353916141 0.652616659555686 BNIP3 1 GO:1900112 regulation of histone H3-K9 trimethylation 1/435 11/18722 0.227920353916141 0.652616659555686 LMNA 1 GO:1900222 negative regulation of amyloid-beta clearance 1/435 11/18722 0.227920353916141 0.652616659555686 LRPAP1 1 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction 1/435 11/18722 0.227920353916141 0.652616659555686 CAV1 1 GO:1902188 positive regulation of viral release from host cell 1/435 11/18722 0.227920353916141 0.652616659555686 DDB1 1 GO:1902337 regulation of apoptotic process involved in morphogenesis 1/435 11/18722 0.227920353916141 0.652616659555686 BMP7 1 GO:1903299 regulation of hexokinase activity 1/435 11/18722 0.227920353916141 0.652616659555686 BAD 1 GO:1904181 positive regulation of membrane depolarization 1/435 11/18722 0.227920353916141 0.652616659555686 PARP1 1 GO:1904729 regulation of intestinal lipid absorption 1/435 11/18722 0.227920353916141 0.652616659555686 LPCAT3 1 GO:1905050 positive regulation of metallopeptidase activity 1/435 11/18722 0.227920353916141 0.652616659555686 CLDN4 1 GO:1905522 negative regulation of macrophage migration 1/435 11/18722 0.227920353916141 0.652616659555686 MIF 1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity 1/435 11/18722 0.227920353916141 0.652616659555686 PKIB 1 GO:2000644 regulation of receptor catabolic process 1/435 11/18722 0.227920353916141 0.652616659555686 ANXA2 1 GO:2001053 regulation of mesenchymal cell apoptotic process 1/435 11/18722 0.227920353916141 0.652616659555686 BMP7 1 GO:0045936 negative regulation of phosphate metabolic process 13/435 441/18722 0.228175613524902 0.652616659555686 GSTP1/CDKN1C/PKIB/MLLT1/FBLN1/BMP7/PARP1/CTDSPL/NR2F2/PARK7/LGALS3/NPM1/CAV1 13 GO:0003208 cardiac ventricle morphogenesis 3/435 71/18722 0.228266791240092 0.652616659555686 DSP/LRP2/LY6E 3 GO:0003281 ventricular septum development 3/435 71/18722 0.228266791240092 0.652616659555686 LMO4/LRP2/GJA5 3 GO:0072078 nephron tubule morphogenesis 3/435 71/18722 0.228266791240092 0.652616659555686 MAGED1/LAMA5/TACSTD2 3 GO:0051235 maintenance of location 10/435 326/18722 0.228725979342444 0.652616659555686 FBN2/MEST/HSP90B1/GJA1/FBN1/PARK7/HILPDA/CALR/KDELR1/CAV1 10 GO:0002347 response to tumor cell 2/435 39/18722 0.229299616912534 0.652616659555686 PRDX2/HSPD1 2 GO:0007618 mating 2/435 39/18722 0.229299616912534 0.652616659555686 APP/SLC6A4 2 GO:0010463 mesenchymal cell proliferation 2/435 39/18722 0.229299616912534 0.652616659555686 BMP7/LMNA 2 GO:0042417 dopamine metabolic process 2/435 39/18722 0.229299616912534 0.652616659555686 COMT/PARK7 2 GO:0046621 negative regulation of organ growth 2/435 39/18722 0.229299616912534 0.652616659555686 GJA1/SLC6A4 2 GO:0003015 heart process 8/435 251/18722 0.23028513306973 0.652616659555686 SOD1/DSP/GJA1/ADRB1/GJA5/DSC2/ATP2B1/CAV1 8 GO:0010563 negative regulation of phosphorus metabolic process 13/435 442/18722 0.230518694002432 0.652616659555686 GSTP1/CDKN1C/PKIB/MLLT1/FBLN1/BMP7/PARP1/CTDSPL/NR2F2/PARK7/LGALS3/NPM1/CAV1 13 GO:0090130 tissue migration 11/435 365/18722 0.230835956140342 0.652616659555686 SERPINF1/NRP2/ANXA3/MET/EFNA1/NR2F2/CALR/FERMT1/AMOT/TACSTD2/PDCD6 11 GO:0008584 male gonad development 5/435 141/18722 0.230984640524843 0.652616659555686 ADGRG1/LRP2/PRDX4/EIF2S2/CCND1 5 GO:0006766 vitamin metabolic process 4/435 106/18722 0.232818987752889 0.652616659555686 SLC2A1/FOLR1/LRP2/SLC19A1 4 GO:0046620 regulation of organ growth 4/435 106/18722 0.232818987752889 0.652616659555686 SOD1/DUSP9/GJA1/SLC6A4 4 GO:0046822 regulation of nucleocytoplasmic transport 4/435 106/18722 0.232818987752889 0.652616659555686 CDH1/HSP90AB1/PARK7/FERMT1 4 GO:0005977 glycogen metabolic process 3/435 72/18722 0.234430538086072 0.652616659555686 PHLDA2/UGP2/AGL 3 GO:1903036 positive regulation of response to wounding 3/435 72/18722 0.234430538086072 0.652616659555686 CLDN4/PRDX2/FERMT1 3 GO:0046546 development of primary male sexual characteristics 5/435 142/18722 0.235260006449222 0.652616659555686 ADGRG1/LRP2/PRDX4/EIF2S2/CCND1 5 GO:0072006 nephron development 5/435 142/18722 0.235260006449222 0.652616659555686 CD24/MAGED1/BMP7/LAMA5/TACSTD2 5 GO:0060828 regulation of canonical Wnt signaling pathway 8/435 253/18722 0.236598031343414 0.652616659555686 RPS12/EGFR/FOLR1/WLS/LGR5/FERMT1/TBL1X/CAV1 8 GO:0006275 regulation of DNA replication 4/435 107/18722 0.237820785997342 0.652616659555686 EGFR/S100A11/SSBP1/STOML2 4 GO:0010927 cellular component assembly involved in morphogenesis 4/435 107/18722 0.237820785997342 0.652616659555686 KRT8/CSRP2/ITGB4/DAG1 4 GO:0032526 response to retinoic acid 4/435 107/18722 0.237820785997342 0.652616659555686 SERPINF1/NDUFA13/GJA1/SLC6A4 4 GO:0051341 regulation of oxidoreductase activity 4/435 107/18722 0.237820785997342 0.652616659555686 EGFR/NDUFA4/PARK7/CAV1 4 GO:0071868 cellular response to monoamine stimulus 4/435 107/18722 0.237820785997342 0.652616659555686 TGM2/GNAS/APP/NSG1 4 GO:0071870 cellular response to catecholamine stimulus 4/435 107/18722 0.237820785997342 0.652616659555686 TGM2/GNAS/APP/NSG1 4 GO:0001936 regulation of endothelial cell proliferation 6/435 179/18722 0.237890246076025 0.652616659555686 NRP2/GJA1/NR2F2/MYDGF/CAV1/PDCD6 6 GO:0010863 positive regulation of phospholipase C activity 2/435 40/18722 0.237924777597808 0.652616659555686 EGFR/PHB 2 GO:0043001 Golgi to plasma membrane protein transport 2/435 40/18722 0.237924777597808 0.652616659555686 KRT18/CLN3 2 GO:0045429 positive regulation of nitric oxide biosynthetic process 2/435 40/18722 0.237924777597808 0.652616659555686 HSP90AB1/ASS1 2 GO:0071276 cellular response to cadmium ion 2/435 40/18722 0.237924777597808 0.652616659555686 SOD1/EGFR 2 GO:0071526 semaphorin-plexin signaling pathway 2/435 40/18722 0.237924777597808 0.652616659555686 NRP2/MET 2 GO:0097352 autophagosome maturation 2/435 40/18722 0.237924777597808 0.652616659555686 VAMP8/CLN3 2 GO:0010632 regulation of epithelial cell migration 9/435 292/18722 0.240222926877668 0.652616659555686 SERPINF1/NRP2/ANXA3/MET/EFNA1/NR2F2/CALR/TACSTD2/PDCD6 9 GO:0006073 cellular glucan metabolic process 3/435 73/18722 0.240623538532556 0.652616659555686 PHLDA2/UGP2/AGL 3 GO:0032456 endocytic recycling 3/435 73/18722 0.240623538532556 0.652616659555686 NSG1/SNX3/RAB17 3 GO:0043299 leukocyte degranulation 3/435 73/18722 0.240623538532556 0.652616659555686 VAMP8/ANXA3/S100A13 3 GO:0044042 glucan metabolic process 3/435 73/18722 0.240623538532556 0.652616659555686 PHLDA2/UGP2/AGL 3 GO:0045739 positive regulation of DNA repair 3/435 73/18722 0.240623538532556 0.652616659555686 EGFR/PARP1/RPS3 3 GO:0072088 nephron epithelium morphogenesis 3/435 73/18722 0.240623538532556 0.652616659555686 MAGED1/LAMA5/TACSTD2 3 GO:0007611 learning or memory 8/435 255/18722 0.242970127109276 0.652616659555686 SERPINF1/EGFR/COMT/ARL6IP5/MME/APP/CLN3/SLC6A4 8 GO:0002696 positive regulation of leukocyte activation 12/435 409/18722 0.244619902131769 0.652616659555686 CD24/VAMP8/HSPD1/PNP/RPS3/SLC39A10/BAD/CD46/MIF/CD55/CAV1/CD47 12 GO:0010876 lipid localization 13/435 448/18722 0.244778804171062 0.652616659555686 ANXA2/SLC2A1/MEST/SLC27A2/CLN3/STARD10/DBI/HILPDA/FIS1/STOML2/KCNN4/CAV1/LPCAT3 13 GO:0006479 protein methylation 6/435 181/18722 0.245551287562782 0.652616659555686 DNMT1/LMNA/SNRPD3/TRMT112/LCMT1/PRMT1 6 GO:0008213 protein alkylation 6/435 181/18722 0.245551287562782 0.652616659555686 DNMT1/LMNA/SNRPD3/TRMT112/LCMT1/PRMT1 6 GO:1905952 regulation of lipid localization 6/435 181/18722 0.245551287562782 0.652616659555686 ANXA2/DBI/HILPDA/FIS1/CAV1/LPCAT3 6 GO:0000012 single strand break repair 1/435 12/18722 0.245869936837763 0.652616659555686 PARP1 1 GO:0001821 histamine secretion 1/435 12/18722 0.245869936837763 0.652616659555686 VAMP8 1 GO:0002024 diet induced thermogenesis 1/435 12/18722 0.245869936837763 0.652616659555686 ADRB1 1 GO:0002182 cytoplasmic translational elongation 1/435 12/18722 0.245869936837763 0.652616659555686 RPLP2 1 GO:0002424 T cell mediated immune response to tumor cell 1/435 12/18722 0.245869936837763 0.652616659555686 HSPD1 1 GO:0002674 negative regulation of acute inflammatory response 1/435 12/18722 0.245869936837763 0.652616659555686 GSTP1 1 GO:0002863 positive regulation of inflammatory response to antigenic stimulus 1/435 12/18722 0.245869936837763 0.652616659555686 PARK7 1 GO:0002903 negative regulation of B cell apoptotic process 1/435 12/18722 0.245869936837763 0.652616659555686 SLC39A10 1 GO:0006534 cysteine metabolic process 1/435 12/18722 0.245869936837763 0.652616659555686 CDO1 1 GO:0006703 estrogen biosynthetic process 1/435 12/18722 0.245869936837763 0.652616659555686 HSD17B1 1 GO:0007320 insemination 1/435 12/18722 0.245869936837763 0.652616659555686 SLC6A4 1 GO:0009086 methionine biosynthetic process 1/435 12/18722 0.245869936837763 0.652616659555686 ADI1 1 GO:0010587 miRNA catabolic process 1/435 12/18722 0.245869936837763 0.652616659555686 LIN28B 1 GO:0010826 negative regulation of centrosome duplication 1/435 12/18722 0.245869936837763 0.652616659555686 NPM1 1 GO:0019627 urea metabolic process 1/435 12/18722 0.245869936837763 0.652616659555686 ASS1 1 GO:0021527 spinal cord association neuron differentiation 1/435 12/18722 0.245869936837763 0.652616659555686 LMO4 1 GO:0021936 regulation of cerebellar granule cell precursor proliferation 1/435 12/18722 0.245869936837763 0.652616659555686 SLC6A4 1 GO:0021978 telencephalon regionalization 1/435 12/18722 0.245869936837763 0.652616659555686 ADGRG1 1 GO:0031453 positive regulation of heterochromatin assembly 1/435 12/18722 0.245869936837763 0.652616659555686 DNMT1 1 GO:0031953 negative regulation of protein autophosphorylation 1/435 12/18722 0.245869936837763 0.652616659555686 CAV1 1 GO:0032096 negative regulation of response to food 1/435 12/18722 0.245869936837763 0.652616659555686 NENF 1 GO:0032099 negative regulation of appetite 1/435 12/18722 0.245869936837763 0.652616659555686 NENF 1 GO:0032105 negative regulation of response to extracellular stimulus 1/435 12/18722 0.245869936837763 0.652616659555686 NENF 1 GO:0032108 negative regulation of response to nutrient levels 1/435 12/18722 0.245869936837763 0.652616659555686 NENF 1 GO:0033182 regulation of histone ubiquitination 1/435 12/18722 0.245869936837763 0.652616659555686 PARK7 1 GO:0034392 negative regulation of smooth muscle cell apoptotic process 1/435 12/18722 0.245869936837763 0.652616659555686 DNMT1 1 GO:0035739 CD4-positive, alpha-beta T cell proliferation 1/435 12/18722 0.245869936837763 0.652616659555686 CD55 1 GO:0042762 regulation of sulfur metabolic process 1/435 12/18722 0.245869936837763 0.652616659555686 COMT 1 GO:0043380 regulation of memory T cell differentiation 1/435 12/18722 0.245869936837763 0.652616659555686 CD46 1 GO:0044650 adhesion of symbiont to host cell 1/435 12/18722 0.245869936837763 0.652616659555686 HSP90AB1 1 GO:0046322 negative regulation of fatty acid oxidation 1/435 12/18722 0.245869936837763 0.652616659555686 ACADVL 1 GO:0046541 saliva secretion 1/435 12/18722 0.245869936837763 0.652616659555686 KCNN4 1 GO:0046606 negative regulation of centrosome cycle 1/435 12/18722 0.245869936837763 0.652616659555686 NPM1 1 GO:0051001 negative regulation of nitric-oxide synthase activity 1/435 12/18722 0.245869936837763 0.652616659555686 CAV1 1 GO:0051095 regulation of helicase activity 1/435 12/18722 0.245869936837763 0.652616659555686 SSBP1 1 GO:0051583 dopamine uptake involved in synaptic transmission 1/435 12/18722 0.245869936837763 0.652616659555686 PARK7 1 GO:0051934 catecholamine uptake involved in synaptic transmission 1/435 12/18722 0.245869936837763 0.652616659555686 PARK7 1 GO:0060442 branching involved in prostate gland morphogenesis 1/435 12/18722 0.245869936837763 0.652616659555686 BMP7 1 GO:0060601 lateral sprouting from an epithelium 1/435 12/18722 0.245869936837763 0.652616659555686 BMP7 1 GO:0061430 bone trabecula morphogenesis 1/435 12/18722 0.245869936837763 0.652616659555686 FBN2 1 GO:0070213 protein auto-ADP-ribosylation 1/435 12/18722 0.245869936837763 0.652616659555686 PARP1 1 GO:0070493 thrombin-activated receptor signaling pathway 1/435 12/18722 0.245869936837763 0.652616659555686 MET 1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain 1/435 12/18722 0.245869936837763 0.652616659555686 GTF2H5 1 GO:0071107 response to parathyroid hormone 1/435 12/18722 0.245869936837763 0.652616659555686 GJA1 1 GO:0071287 cellular response to manganese ion 1/435 12/18722 0.245869936837763 0.652616659555686 APP 1 GO:0071472 cellular response to salt stress 1/435 12/18722 0.245869936837763 0.652616659555686 AKR1B1 1 GO:0071941 nitrogen cycle metabolic process 1/435 12/18722 0.245869936837763 0.652616659555686 ASS1 1 GO:0072182 regulation of nephron tubule epithelial cell differentiation 1/435 12/18722 0.245869936837763 0.652616659555686 CD24 1 GO:0072376 protein activation cascade 1/435 12/18722 0.245869936837763 0.652616659555686 FBLN1 1 GO:0072520 seminiferous tubule development 1/435 12/18722 0.245869936837763 0.652616659555686 ADGRG1 1 GO:0086067 AV node cell to bundle of His cell communication 1/435 12/18722 0.245869936837763 0.652616659555686 GJA5 1 GO:0090085 regulation of protein deubiquitination 1/435 12/18722 0.245869936837763 0.652616659555686 PARK7 1 GO:0090385 phagosome-lysosome fusion 1/435 12/18722 0.245869936837763 0.652616659555686 CLN3 1 GO:0090677 reversible differentiation 1/435 12/18722 0.245869936837763 0.652616659555686 DNMT1 1 GO:0097152 mesenchymal cell apoptotic process 1/435 12/18722 0.245869936837763 0.652616659555686 BMP7 1 GO:0098974 postsynaptic actin cytoskeleton organization 1/435 12/18722 0.245869936837763 0.652616659555686 WASF2 1 GO:0120263 positive regulation of heterochromatin organization 1/435 12/18722 0.245869936837763 0.652616659555686 DNMT1 1 GO:1903332 regulation of protein folding 1/435 12/18722 0.245869936837763 0.652616659555686 PDCD5 1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA 1/435 12/18722 0.245869936837763 0.652616659555686 EGFR 1 GO:1904748 regulation of apoptotic process involved in development 1/435 12/18722 0.245869936837763 0.652616659555686 BMP7 1 GO:1905245 regulation of aspartic-type peptidase activity 1/435 12/18722 0.245869936837763 0.652616659555686 EFNA1 1 GO:1905709 negative regulation of membrane permeability 1/435 12/18722 0.245869936837763 0.652616659555686 BNIP3 1 GO:1990034 calcium ion export across plasma membrane 1/435 12/18722 0.245869936837763 0.652616659555686 ATP2B1 1 GO:2000303 regulation of ceramide biosynthetic process 1/435 12/18722 0.245869936837763 0.652616659555686 ORMDL1 1 GO:2000561 regulation of CD4-positive, alpha-beta T cell proliferation 1/435 12/18722 0.245869936837763 0.652616659555686 CD55 1 GO:2000628 regulation of miRNA metabolic process 1/435 12/18722 0.245869936837763 0.652616659555686 LIN28B 1 GO:2001204 regulation of osteoclast development 1/435 12/18722 0.245869936837763 0.652616659555686 FBN1 1 GO:1903522 regulation of blood circulation 8/435 256/18722 0.246177641463389 0.652616659555686 EGFR/DSP/GJA1/ADRB1/GJA5/DSC2/ATP2B1/CAV1 8 GO:0031062 positive regulation of histone methylation 2/435 41/18722 0.246566061671911 0.652616659555686 DNMT1/LMNA 2 GO:0032733 positive regulation of interleukin-10 production 2/435 41/18722 0.246566061671911 0.652616659555686 HSPD1/CD46 2 GO:0042307 positive regulation of protein import into nucleus 2/435 41/18722 0.246566061671911 0.652616659555686 CDH1/HSP90AB1 2 GO:1904407 positive regulation of nitric oxide metabolic process 2/435 41/18722 0.246566061671911 0.652616659555686 HSP90AB1/ASS1 2 GO:1905314 semi-lunar valve development 2/435 41/18722 0.246566061671911 0.652616659555686 GJA5/EFNA1 2 GO:0048844 artery morphogenesis 3/435 74/18722 0.246843489084412 0.652914228814852 FOLR1/LRP2/GJA5 3 GO:0072009 nephron epithelium development 4/435 109/18722 0.247898553864406 0.653005654143134 CD24/MAGED1/LAMA5/TACSTD2 4 GO:0043524 negative regulation of neuron apoptotic process 5/435 145/18722 0.24821569879069 0.653005654143134 SOD1/HSPD1/CLN3/HSP90AB1/PARK7 5 GO:0061351 neural precursor cell proliferation 5/435 145/18722 0.24821569879069 0.653005654143134 SPINT2/SPINT1/ADGRG1/LRP2/SLC6A4 5 GO:0046879 hormone secretion 9/435 295/18722 0.24918031142101 0.653005654143134 FAM3B/EGFR/VAMP8/GJA1/PARK7/MPC2/HMGN3/BAD/PHPT1 9 GO:0002064 epithelial cell development 7/435 220/18722 0.25192501519203 0.653005654143134 SPINT2/SOD1/MET/ADAMTSL4/AKR1B1/BAD/S1PR2 7 GO:0097529 myeloid leukocyte migration 7/435 220/18722 0.25192501519203 0.653005654143134 BSG/PPIB/RPS19/C1QBP/LGALS3/MIF/CD47 7 GO:0050890 cognition 9/435 296/18722 0.252191079654877 0.653005654143134 SERPINF1/EGFR/COMT/TUSC3/ARL6IP5/MME/APP/CLN3/SLC6A4 9 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 5/435 146/18722 0.25257490575261 0.653005654143134 ADGRG1/GNAS/ADRB1/LGR5/S1PR2 5 GO:0045580 regulation of T cell differentiation 5/435 146/18722 0.25257490575261 0.653005654143134 SOD1/PRDX2/PNP/BAD/CD46 5 GO:0042593 glucose homeostasis 8/435 258/18722 0.252634122928701 0.653005654143134 SERPINF1/FAM3B/PARK7/MPC2/HMGN3/BAD/FIS1/PHPT1 8 GO:0009063 cellular amino acid catabolic process 4/435 110/18722 0.252972071620757 0.653005654143134 GCSH/ECHS1/GLDC/CDO1 4 GO:0018958 phenol-containing compound metabolic process 4/435 110/18722 0.252972071620757 0.653005654143134 COMT/PARK7/AKR1B1/LY6E 4 GO:0006278 RNA-dependent DNA biosynthetic process 3/435 75/18722 0.253088121979728 0.653005654143134 PKIB/HSP90AB1/NHP2 3 GO:0048662 negative regulation of smooth muscle cell proliferation 3/435 75/18722 0.253088121979728 0.653005654143134 GSTP1/COMT/S1PR2 3 GO:0000266 mitochondrial fission 2/435 42/18722 0.255218077387281 0.653005654143134 FIS1/BNIP3 2 GO:0007212 dopamine receptor signaling pathway 2/435 42/18722 0.255218077387281 0.653005654143134 GNAS/NSG1 2 GO:0009154 purine ribonucleotide catabolic process 2/435 42/18722 0.255218077387281 0.653005654143134 PNP/NUDT4 2 GO:0014912 negative regulation of smooth muscle cell migration 2/435 42/18722 0.255218077387281 0.653005654143134 GSTP1/S1PR2 2 GO:0016601 Rac protein signal transduction 2/435 42/18722 0.255218077387281 0.653005654143134 HACD3/WASF2 2 GO:0021879 forebrain neuron differentiation 2/435 42/18722 0.255218077387281 0.653005654143134 NRP2/UQCRQ 2 GO:0030890 positive regulation of B cell proliferation 2/435 42/18722 0.255218077387281 0.653005654143134 SLC39A10/MIF 2 GO:0033574 response to testosterone 2/435 42/18722 0.255218077387281 0.653005654143134 CALR/BAD 2 GO:0045047 protein targeting to ER 2/435 42/18722 0.255218077387281 0.653005654143134 SRP14/SPCS1 2 GO:0045214 sarcomere organization 2/435 42/18722 0.255218077387281 0.653005654143134 KRT8/CSRP2 2 GO:0045687 positive regulation of glial cell differentiation 2/435 42/18722 0.255218077387281 0.653005654143134 SPINT1/DAG1 2 GO:1900274 regulation of phospholipase C activity 2/435 42/18722 0.255218077387281 0.653005654143134 EGFR/PHB 2 GO:0033500 carbohydrate homeostasis 8/435 259/18722 0.255882493278277 0.653005654143134 SERPINF1/FAM3B/PARK7/MPC2/HMGN3/BAD/FIS1/PHPT1 8 GO:0009896 positive regulation of catabolic process 14/435 492/18722 0.256152748979423 0.653005654143134 LRP2/NDUFA13/APP/GJA1/BCAP31/PARK7/BAD/TMEM59/LIN28B/SCOC/PSMC1/DDB1/BNIP3/CAV1 14 GO:0071867 response to monoamine 4/435 111/18722 0.25806705551021 0.653005654143134 TGM2/GNAS/APP/NSG1 4 GO:0071869 response to catecholamine 4/435 111/18722 0.25806705551021 0.653005654143134 TGM2/GNAS/APP/NSG1 4 GO:0001937 negative regulation of endothelial cell proliferation 3/435 76/18722 0.259355206048571 0.653005654143134 GJA1/NR2F2/CAV1 3 GO:0014823 response to activity 3/435 76/18722 0.259355206048571 0.653005654143134 HSPD1/FIS1/UQCRC1 3 GO:0021536 diencephalon development 3/435 76/18722 0.259355206048571 0.653005654143134 CDH1/NRP2/UQCRQ 3 GO:0043484 regulation of RNA splicing 5/435 148/18722 0.261349688360054 0.653005654143134 MBNL3/PRDX6/C1QBP/RPS26/NPM1 5 GO:0044839 cell cycle G2/M phase transition 5/435 148/18722 0.261349688360054 0.653005654143134 APP/NPM1/SKP2/CCND1/LCMT1 5 GO:1903900 regulation of viral life cycle 5/435 148/18722 0.261349688360054 0.653005654143134 P4HB/HACD3/LY6E/SNX3/DDB1 5 GO:0001886 endothelial cell morphogenesis 1/435 13/18722 0.26340315850936 0.653005654143134 MET 1 GO:0006000 fructose metabolic process 1/435 13/18722 0.26340315850936 0.653005654143134 AKR1B1 1 GO:0009143 nucleoside triphosphate catabolic process 1/435 13/18722 0.26340315850936 0.653005654143134 SMPDL3A 1 GO:0010635 regulation of mitochondrial fusion 1/435 13/18722 0.26340315850936 0.653005654143134 BNIP3 1 GO:0010960 magnesium ion homeostasis 1/435 13/18722 0.26340315850936 0.653005654143134 EGFR 1 GO:0014029 neural crest formation 1/435 13/18722 0.26340315850936 0.653005654143134 PDCD6 1 GO:0014745 negative regulation of muscle adaptation 1/435 13/18722 0.26340315850936 0.653005654143134 LMNA 1 GO:0016322 neuron remodeling 1/435 13/18722 0.26340315850936 0.653005654143134 APP 1 GO:0019336 phenol-containing compound catabolic process 1/435 13/18722 0.26340315850936 0.653005654143134 COMT 1 GO:0021514 ventral spinal cord interneuron differentiation 1/435 13/18722 0.26340315850936 0.653005654143134 LMO4 1 GO:0021794 thalamus development 1/435 13/18722 0.26340315850936 0.653005654143134 UQCRQ 1 GO:0021819 layer formation in cerebral cortex 1/435 13/18722 0.26340315850936 0.653005654143134 ADGRG1 1 GO:0021859 pyramidal neuron differentiation 1/435 13/18722 0.26340315850936 0.653005654143134 UQCRQ 1 GO:0030836 positive regulation of actin filament depolymerization 1/435 13/18722 0.26340315850936 0.653005654143134 DSTN 1 GO:0031053 primary miRNA processing 1/435 13/18722 0.26340315850936 0.653005654143134 LIN28B 1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 1/435 13/18722 0.26340315850936 0.653005654143134 PRDX2 1 GO:0032042 mitochondrial DNA metabolic process 1/435 13/18722 0.26340315850936 0.653005654143134 PARP1 1 GO:0032429 regulation of phospholipase A2 activity 1/435 13/18722 0.26340315850936 0.653005654143134 EGFR 1 GO:0033689 negative regulation of osteoblast proliferation 1/435 13/18722 0.26340315850936 0.653005654143134 ATRAID 1 GO:0034309 primary alcohol biosynthetic process 1/435 13/18722 0.26340315850936 0.653005654143134 PARK7 1 GO:0034982 mitochondrial protein processing 1/435 13/18722 0.26340315850936 0.653005654143134 STOML2 1 GO:0036462 TRAIL-activated apoptotic signaling pathway 1/435 13/18722 0.26340315850936 0.653005654143134 PARK7 1 GO:0042308 negative regulation of protein import into nucleus 1/435 13/18722 0.26340315850936 0.653005654143134 FERMT1 1 GO:0042538 hyperosmotic salinity response 1/435 13/18722 0.26340315850936 0.653005654143134 AKR1B1 1 GO:0042541 hemoglobin biosynthetic process 1/435 13/18722 0.26340315850936 0.653005654143134 PRMT1 1 GO:0042659 regulation of cell fate specification 1/435 13/18722 0.26340315850936 0.653005654143134 LMO4 1 GO:0043379 memory T cell differentiation 1/435 13/18722 0.26340315850936 0.653005654143134 CD46 1 GO:0044090 positive regulation of vacuole organization 1/435 13/18722 0.26340315850936 0.653005654143134 ANXA2 1 GO:0044794 positive regulation by host of viral process 1/435 13/18722 0.26340315850936 0.653005654143134 PPIB 1 GO:0048012 hepatocyte growth factor receptor signaling pathway 1/435 13/18722 0.26340315850936 0.653005654143134 MET 1 GO:0048207 vesicle targeting, rough ER to cis-Golgi 1/435 13/18722 0.26340315850936 0.653005654143134 PDCD6 1 GO:0048208 COPII vesicle coating 1/435 13/18722 0.26340315850936 0.653005654143134 PDCD6 1 GO:0048266 behavioral response to pain 1/435 13/18722 0.26340315850936 0.653005654143134 VWA1 1 GO:0048820 hair follicle maturation 1/435 13/18722 0.26340315850936 0.653005654143134 FERMT1 1 GO:0051481 negative regulation of cytosolic calcium ion concentration 1/435 13/18722 0.26340315850936 0.653005654143134 ATP2B1 1 GO:0060707 trophoblast giant cell differentiation 1/435 13/18722 0.26340315850936 0.653005654143134 NR2F2 1 GO:0061000 negative regulation of dendritic spine development 1/435 13/18722 0.26340315850936 0.653005654143134 EFNA1 1 GO:0070486 leukocyte aggregation 1/435 13/18722 0.26340315850936 0.653005654143134 BMP7 1 GO:0070914 UV-damage excision repair 1/435 13/18722 0.26340315850936 0.653005654143134 DDB1 1 GO:0090042 tubulin deacetylation 1/435 13/18722 0.26340315850936 0.653005654143134 BEX4 1 GO:0090153 regulation of sphingolipid biosynthetic process 1/435 13/18722 0.26340315850936 0.653005654143134 ORMDL1 1 GO:0090158 endoplasmic reticulum membrane organization 1/435 13/18722 0.26340315850936 0.653005654143134 LPCAT3 1 GO:0106074 aminoacyl-tRNA metabolism involved in translational fidelity 1/435 13/18722 0.26340315850936 0.653005654143134 IARS2 1 GO:1900272 negative regulation of long-term synaptic potentiation 1/435 13/18722 0.26340315850936 0.653005654143134 APP 1 GO:1901096 regulation of autophagosome maturation 1/435 13/18722 0.26340315850936 0.653005654143134 CLN3 1 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance 1/435 13/18722 0.26340315850936 0.653005654143134 NRP2 1 GO:1902947 regulation of tau-protein kinase activity 1/435 13/18722 0.26340315850936 0.653005654143134 HSP90AB1 1 GO:1904478 regulation of intestinal absorption 1/435 13/18722 0.26340315850936 0.653005654143134 LPCAT3 1 GO:1904590 negative regulation of protein import 1/435 13/18722 0.26340315850936 0.653005654143134 FERMT1 1 GO:1905038 regulation of membrane lipid metabolic process 1/435 13/18722 0.26340315850936 0.653005654143134 ORMDL1 1 GO:1905064 negative regulation of vascular associated smooth muscle cell differentiation 1/435 13/18722 0.26340315850936 0.653005654143134 DNMT1 1 GO:1905244 regulation of modification of synaptic structure 1/435 13/18722 0.26340315850936 0.653005654143134 CLN3 1 GO:1905269 positive regulation of chromatin organization 1/435 13/18722 0.26340315850936 0.653005654143134 DNMT1 1 GO:1905907 negative regulation of amyloid fibril formation 1/435 13/18722 0.26340315850936 0.653005654143134 PFDN1 1 GO:2001023 regulation of response to drug 1/435 13/18722 0.26340315850936 0.653005654143134 ADIRF 1 GO:0001504 neurotransmitter uptake 2/435 43/18722 0.263875673736384 0.653005654143134 SLC6A4/PARK7 2 GO:0006458 'de novo' protein folding 2/435 43/18722 0.263875673736384 0.653005654143134 HSPD1/HSPE1 2 GO:0009268 response to pH 2/435 43/18722 0.263875673736384 0.653005654143134 SERPINF1/GJA1 2 GO:0014002 astrocyte development 2/435 43/18722 0.263875673736384 0.653005654143134 EGFR/APP 2 GO:0035794 positive regulation of mitochondrial membrane permeability 2/435 43/18722 0.263875673736384 0.653005654143134 HEBP2/BNIP3 2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2/435 43/18722 0.263875673736384 0.653005654143134 MIF/SHISA5 2 GO:0045776 negative regulation of blood pressure 2/435 43/18722 0.263875673736384 0.653005654143134 ADRB1/GJA5 2 GO:0061383 trabecula morphogenesis 2/435 43/18722 0.263875673736384 0.653005654143134 FBN2/BMP7 2 GO:0098815 modulation of excitatory postsynaptic potential 2/435 43/18722 0.263875673736384 0.653005654143134 APP/S1PR2 2 GO:0120178 steroid hormone biosynthetic process 2/435 43/18722 0.263875673736384 0.653005654143134 HSD17B1/AKR1B1 2 GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation 2/435 43/18722 0.263875673736384 0.653005654143134 GSTP1/S1PR2 2 GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 2/435 43/18722 0.263875673736384 0.653005654143134 IFI6/PRDX2 2 GO:0071478 cellular response to radiation 6/435 186/18722 0.265004655690922 0.655219377898426 ADIRF/PARP1/MME/GTF2H5/NPM1/DDB1 6 GO:0006367 transcription initiation from RNA polymerase II promoter 3/435 77/18722 0.265642547483638 0.655219377898426 GTF2H5/GTF2A2/POLR2I 3 GO:0031016 pancreas development 3/435 77/18722 0.265642547483638 0.655219377898426 MET/WLS/BAD 3 GO:0048644 muscle organ morphogenesis 3/435 77/18722 0.265642547483638 0.655219377898426 DSP/LRP2/LY6E 3 GO:0032368 regulation of lipid transport 5/435 149/18722 0.265763735538785 0.655219377898426 ANXA2/DBI/FIS1/CAV1/LPCAT3 5 GO:0051592 response to calcium ion 5/435 149/18722 0.265763735538785 0.655219377898426 EGFR/BAD/CCND1/CAV1/PDCD6 5 GO:0006753 nucleoside phosphate metabolic process 14/435 497/18722 0.267976736633823 0.659426686517366 QPRT/PARP1/ACSS1/APP/PNP/PARK7/TECR/NUDT4/MPC2/BAD/REXO2/STOML2/TPST2/SMPDL3A 14 GO:0030900 forebrain development 11/435 379/18722 0.268161880080458 0.659426686517366 ADGRG1/SLC2A1/CDH1/NRP2/UQCRQ/LRP2/ANXA3/APP/NR2F2/BAD/BNIP3 11 GO:0008037 cell recognition 7/435 225/18722 0.269689464945537 0.659426686517366 BSG/COLEC12/FOLR1/SPESP1/APP/LGALS3/CADM1 7 GO:0050769 positive regulation of neurogenesis 7/435 225/18722 0.269689464945537 0.659426686517366 SERPINF1/SPINT1/EGFR/LRP2/TGM2/MME/DAG1 7 GO:0032371 regulation of sterol transport 3/435 78/18722 0.271947990527085 0.659426686517366 ANXA2/CAV1/LPCAT3 3 GO:0032374 regulation of cholesterol transport 3/435 78/18722 0.271947990527085 0.659426686517366 ANXA2/CAV1/LPCAT3 3 GO:0090559 regulation of membrane permeability 3/435 78/18722 0.271947990527085 0.659426686517366 HEBP2/BAD/BNIP3 3 GO:0005978 glycogen biosynthetic process 2/435 44/18722 0.272533932219155 0.659426686517366 UGP2/AGL 2 GO:0009250 glucan biosynthetic process 2/435 44/18722 0.272533932219155 0.659426686517366 UGP2/AGL 2 GO:0030521 androgen receptor signaling pathway 2/435 44/18722 0.272533932219155 0.659426686517366 PARK7/PHB 2 GO:0031295 T cell costimulation 2/435 44/18722 0.272533932219155 0.659426686517366 CD24/CAV1 2 GO:0046006 regulation of activated T cell proliferation 2/435 44/18722 0.272533932219155 0.659426686517366 CD24/RPS3 2 GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT 2/435 44/18722 0.272533932219155 0.659426686517366 IL10RB/AKR1B1 2 GO:0048806 genitalia development 2/435 44/18722 0.272533932219155 0.659426686517366 LRP2/DNAJC19 2 GO:0050999 regulation of nitric-oxide synthase activity 2/435 44/18722 0.272533932219155 0.659426686517366 EGFR/CAV1 2 GO:0097178 ruffle assembly 2/435 44/18722 0.272533932219155 0.659426686517366 TACSTD2/CAV1 2 GO:1903214 regulation of protein targeting to mitochondrion 2/435 44/18722 0.272533932219155 0.659426686517366 PDCD5/LMAN1 2 GO:1903573 negative regulation of response to endoplasmic reticulum stress 2/435 44/18722 0.272533932219155 0.659426686517366 PARK7/LPCAT3 2 GO:0050867 positive regulation of cell activation 12/435 420/18722 0.272879728667787 0.659426686517366 CD24/VAMP8/HSPD1/PNP/RPS3/SLC39A10/BAD/CD46/MIF/CD55/CAV1/CD47 12 GO:0051495 positive regulation of cytoskeleton organization 7/435 226/18722 0.273282859361839 0.659426686517366 MET/RPS3/S100A10/DSTN/RHOC/WASF2/CD47 7 GO:0021987 cerebral cortex development 4/435 114/18722 0.273468768903724 0.659426686517366 ADGRG1/SLC2A1/BAD/BNIP3 4 GO:0046660 female sex differentiation 4/435 114/18722 0.273468768903724 0.659426686517366 SOD1/LRP2/IDH1/NR2F2 4 GO:0048592 eye morphogenesis 5/435 151/18722 0.274641332506626 0.659426686517366 EFEMP1/FBN2/BMP7/FBN1/TENM3 5 GO:0007411 axon guidance 7/435 227/18722 0.276888836027778 0.659426686517366 BSG/NRP2/BMP7/APP/EFNA1/DAG1/LAMA5 7 GO:0000245 spliceosomal complex assembly 3/435 79/18722 0.27826941807762 0.659426686517366 SNRPG/SNRPD2/SNRPE 3 GO:0001895 retina homeostasis 3/435 79/18722 0.27826941807762 0.659426686517366 SOD1/PRDX1/SLC2A1 3 GO:0030278 regulation of ossification 4/435 115/18722 0.278637626332485 0.659426686517366 FBN2/BMP7/ATRAID/ATP2B1 4 GO:0043279 response to alkaloid 4/435 115/18722 0.278637626332485 0.659426686517366 TGM2/HSPD1/HSP90AB1/UQCRC1 4 GO:1901989 positive regulation of cell cycle phase transition 4/435 115/18722 0.278637626332485 0.659426686517366 EGFR/APP/NPM1/CCND1 4 GO:0051092 positive regulation of NF-kappaB transcription factor activity 5/435 152/18722 0.27910336486567 0.659426686517366 APP/RPS3/LAMTOR5/NPM1/CAV1 5 GO:0097485 neuron projection guidance 7/435 228/18722 0.280506999664065 0.659426686517366 BSG/NRP2/BMP7/APP/EFNA1/DAG1/LAMA5 7 GO:0000054 ribosomal subunit export from nucleus 1/435 14/18722 0.28052965517131 0.659426686517366 NPM1 1 GO:0001771 immunological synapse formation 1/435 14/18722 0.28052965517131 0.659426686517366 LGALS3 1 GO:0002091 negative regulation of receptor internalization 1/435 14/18722 0.28052965517131 0.659426686517366 LRPAP1 1 GO:0002864 regulation of acute inflammatory response to antigenic stimulus 1/435 14/18722 0.28052965517131 0.659426686517366 PARK7 1 GO:0003376 sphingosine-1-phosphate receptor signaling pathway 1/435 14/18722 0.28052965517131 0.659426686517366 S1PR2 1 GO:0006465 signal peptide processing 1/435 14/18722 0.28052965517131 0.659426686517366 SPCS1 1 GO:0006596 polyamine biosynthetic process 1/435 14/18722 0.28052965517131 0.659426686517366 SMS 1 GO:0009158 ribonucleoside monophosphate catabolic process 1/435 14/18722 0.28052965517131 0.659426686517366 PNP 1 GO:0009159 deoxyribonucleoside monophosphate catabolic process 1/435 14/18722 0.28052965517131 0.659426686517366 PNP 1 GO:0014874 response to stimulus involved in regulation of muscle adaptation 1/435 14/18722 0.28052965517131 0.659426686517366 DAG1 1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway 1/435 14/18722 0.28052965517131 0.659426686517366 PDCD6 1 GO:0031054 pre-miRNA processing 1/435 14/18722 0.28052965517131 0.659426686517366 LIN28B 1 GO:0033008 positive regulation of mast cell activation involved in immune response 1/435 14/18722 0.28052965517131 0.659426686517366 VAMP8 1 GO:0033750 ribosome localization 1/435 14/18722 0.28052965517131 0.659426686517366 NPM1 1 GO:0034616 response to laminar fluid shear stress 1/435 14/18722 0.28052965517131 0.659426686517366 ASS1 1 GO:0036295 cellular response to increased oxygen levels 1/435 14/18722 0.28052965517131 0.659426686517366 CAV1 1 GO:0038166 angiotensin-activated signaling pathway 1/435 14/18722 0.28052965517131 0.659426686517366 CAV1 1 GO:0043306 positive regulation of mast cell degranulation 1/435 14/18722 0.28052965517131 0.659426686517366 VAMP8 1 GO:0043558 regulation of translational initiation in response to stress 1/435 14/18722 0.28052965517131 0.659426686517366 NPM1 1 GO:0045579 positive regulation of B cell differentiation 1/435 14/18722 0.28052965517131 0.659426686517366 BAD 1 GO:0048172 regulation of short-term neuronal synaptic plasticity 1/435 14/18722 0.28052965517131 0.659426686517366 CLN3 1 GO:0048291 isotype switching to IgG isotypes 1/435 14/18722 0.28052965517131 0.659426686517366 HSPD1 1 GO:0050667 homocysteine metabolic process 1/435 14/18722 0.28052965517131 0.659426686517366 COMT 1 GO:0060081 membrane hyperpolarization 1/435 14/18722 0.28052965517131 0.659426686517366 PARK7 1 GO:0060088 auditory receptor cell stereocilium organization 1/435 14/18722 0.28052965517131 0.659426686517366 SOD1 1 GO:0071236 cellular response to antibiotic 1/435 14/18722 0.28052965517131 0.659426686517366 RPL23 1 GO:0072160 nephron tubule epithelial cell differentiation 1/435 14/18722 0.28052965517131 0.659426686517366 CD24 1 GO:0072498 embryonic skeletal joint development 1/435 14/18722 0.28052965517131 0.659426686517366 BMP7 1 GO:0086103 G protein-coupled receptor signaling pathway involved in heart process 1/435 14/18722 0.28052965517131 0.659426686517366 CAV1 1 GO:0090308 regulation of DNA methylation-dependent heterochromatin assembly 1/435 14/18722 0.28052965517131 0.659426686517366 DNMT1 1 GO:0090715 immunological memory formation process 1/435 14/18722 0.28052965517131 0.659426686517366 CD46 1 GO:0099188 postsynaptic cytoskeleton organization 1/435 14/18722 0.28052965517131 0.659426686517366 WASF2 1 GO:0099638 endosome to plasma membrane protein transport 1/435 14/18722 0.28052965517131 0.659426686517366 NSG1 1 GO:1901722 regulation of cell proliferation involved in kidney development 1/435 14/18722 0.28052965517131 0.659426686517366 BMP7 1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/435 14/18722 0.28052965517131 0.659426686517366 MIF 1 GO:1902916 positive regulation of protein polyubiquitination 1/435 14/18722 0.28052965517131 0.659426686517366 SKP2 1 GO:1905208 negative regulation of cardiocyte differentiation 1/435 14/18722 0.28052965517131 0.659426686517366 EGFR 1 GO:2001140 positive regulation of phospholipid transport 1/435 14/18722 0.28052965517131 0.659426686517366 DBI 1 GO:0009566 fertilization 6/435 190/18722 0.280841738684385 0.659426686517366 FOLR1/SPESP1/SLIRP/NR2F2/PARK7/CD46 6 GO:0006903 vesicle targeting 2/435 45/18722 0.281188158861616 0.659426686517366 TMED9/PDCD6 2 GO:0030850 prostate gland development 2/435 45/18722 0.281188158861616 0.659426686517366 SERPINF1/BMP7 2 GO:0031670 cellular response to nutrient 2/435 45/18722 0.281188158861616 0.659426686517366 FOLR1/ATP2B1 2 GO:0035307 positive regulation of protein dephosphorylation 2/435 45/18722 0.281188158861616 0.659426686517366 HSP90AB1/SLC39A10 2 GO:0071364 cellular response to epidermal growth factor stimulus 2/435 45/18722 0.281188158861616 0.659426686517366 GSTP1/EGFR 2 GO:0009914 hormone transport 9/435 306/18722 0.282923945648527 0.659426686517366 FAM3B/EGFR/VAMP8/GJA1/PARK7/MPC2/HMGN3/BAD/PHPT1 9 GO:0007338 single fertilization 5/435 153/18722 0.283579879071577 0.659426686517366 FOLR1/SPESP1/SLIRP/PARK7/CD46 5 GO:0001649 osteoblast differentiation 7/435 229/18722 0.284136954567802 0.659426686517366 FBN2/BMP7/HSPE1/RRBP1/ATRAID/MSX2/PHB 7 GO:0007422 peripheral nervous system development 3/435 80/18722 0.284604752221839 0.659426686517366 SOD1/ITGB4/DAG1 3 GO:0048145 regulation of fibroblast proliferation 3/435 80/18722 0.284604752221839 0.659426686517366 ANXA2/GSTP1/MIF 3 GO:0042326 negative regulation of phosphorylation 11/435 385/18722 0.284735344263471 0.659426686517366 GSTP1/CDKN1C/PKIB/MLLT1/FBLN1/BMP7/CTDSPL/NR2F2/PARK7/NPM1/CAV1 11 GO:0030595 leukocyte chemotaxis 7/435 230/18722 0.28777830474101 0.659426686517366 BSG/PPIB/RPS19/C1QBP/LGALS3/CALR/MIF 7 GO:0030856 regulation of epithelial cell differentiation 5/435 154/18722 0.288070123203904 0.659426686517366 CD24/BAD/CCND1/CAV1/S1PR2 5 GO:0006909 phagocytosis 9/435 308/18722 0.289194218005995 0.659426686517366 SOD1/COLEC12/TGM2/ANXA3/MET/CLN3/CALR/SNX3/CD47 9 GO:0006195 purine nucleotide catabolic process 2/435 46/18722 0.28983387647848 0.659426686517366 PNP/NUDT4 2 GO:0006383 transcription by RNA polymerase III 2/435 46/18722 0.28983387647848 0.659426686517366 PRDX5/POLR2L 2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 2/435 46/18722 0.28983387647848 0.659426686517366 TENM3/CADM1 2 GO:0031294 lymphocyte costimulation 2/435 46/18722 0.28983387647848 0.659426686517366 CD24/CAV1 2 GO:0042398 cellular modified amino acid biosynthetic process 2/435 46/18722 0.28983387647848 0.659426686517366 ALDH7A1/PARK7 2 GO:0045851 pH reduction 2/435 46/18722 0.28983387647848 0.659426686517366 CLN3/ATP6V1B1 2 GO:0060976 coronary vasculature development 2/435 46/18722 0.28983387647848 0.659426686517366 LRP2/ADAMTS6 2 GO:0072599 establishment of protein localization to endoplasmic reticulum 2/435 46/18722 0.28983387647848 0.659426686517366 SRP14/SPCS1 2 GO:0090329 regulation of DNA-dependent DNA replication 2/435 46/18722 0.28983387647848 0.659426686517366 SSBP1/STOML2 2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 2/435 46/18722 0.28983387647848 0.659426686517366 EGFR/CCND1 2 GO:2000107 negative regulation of leukocyte apoptotic process 2/435 46/18722 0.28983387647848 0.659426686517366 SLC39A10/EFNA1 2 GO:0009100 glycoprotein metabolic process 11/435 387/18722 0.2903268544245 0.659426686517366 CTSL/GALNT11/TUSC3/EXTL2/DDOST/RPN2/PARK7/OSTC/TMEM59/CHPF/TMEM258 11 GO:0000422 autophagy of mitochondrion 3/435 81/18722 0.290951954693579 0.659426686517366 PARK7/FIS1/BNIP3 3 GO:0001523 retinoid metabolic process 3/435 81/18722 0.290951954693579 0.659426686517366 LRP2/ADH5/AKR1B1 3 GO:0021954 central nervous system neuron development 3/435 81/18722 0.290951954693579 0.659426686517366 NRP2/UQCRQ/HSP90AB1 3 GO:0048144 fibroblast proliferation 3/435 81/18722 0.290951954693579 0.659426686517366 ANXA2/GSTP1/MIF 3 GO:0051817 modulation of process of other organism involved in symbiotic interaction 3/435 81/18722 0.290951954693579 0.659426686517366 PPIB/DAG1/PHB 3 GO:0060968 regulation of gene silencing 3/435 81/18722 0.290951954693579 0.659426686517366 EGFR/DNMT1/LIN28B 3 GO:0061726 mitochondrion disassembly 3/435 81/18722 0.290951954693579 0.659426686517366 PARK7/FIS1/BNIP3 3 GO:1903533 regulation of protein targeting 3/435 81/18722 0.290951954693579 0.659426686517366 PDCD5/LMAN1/FIS1 3 GO:2000106 regulation of leukocyte apoptotic process 3/435 81/18722 0.290951954693579 0.659426686517366 SLC39A10/EFNA1/LGALS3 3 GO:0032103 positive regulation of response to external stimulus 12/435 427/18722 0.291395469299399 0.659426686517366 EGFR/VAMP8/TGM2/RPS19/MET/HSPD1/APP/PARK7/C1QBP/CALR/CADM1/CD47 12 GO:0045732 positive regulation of protein catabolic process 7/435 231/18722 0.291430654017442 0.659426686517366 LRP2/NDUFA13/GJA1/BCAP31/PSMC1/DDB1/CAV1 7 GO:0006606 protein import into nucleus 5/435 155/18722 0.292573348610736 0.659426686517366 CDH1/RPL23/HSP90AB1/LMNA/FERMT1 5 GO:0006665 sphingolipid metabolic process 5/435 155/18722 0.292573348610736 0.659426686517366 DEGS1/SERINC2/HACD3/TECR/ORMDL1 5 GO:0046434 organophosphate catabolic process 5/435 155/18722 0.292573348610736 0.659426686517366 PNP/IDH1/PRDX6/NUDT4/SMPDL3A 5 GO:0001935 endothelial cell proliferation 6/435 193/18722 0.292857323042834 0.659426686517366 NRP2/GJA1/NR2F2/MYDGF/CAV1/PDCD6 6 GO:0002764 immune response-regulating signaling pathway 13/435 468/18722 0.294533506981722 0.659426686517366 CD24/COLEC12/HSPD1/RPS3/SLC39A10/C1QBP/LGALS3/PHB/STOML2/KCNN4/PHPT1/CAV1/CD47 13 GO:0060326 cell chemotaxis 9/435 310/18722 0.295501102499504 0.659426686517366 GSTP1/BSG/PPIB/RPS19/MET/C1QBP/LGALS3/CALR/MIF 9 GO:0050777 negative regulation of immune response 6/435 194/18722 0.296885936381861 0.659426686517366 RPS19/CD59/C1QBP/LGALS3/CD46/CD55 6 GO:0035051 cardiocyte differentiation 5/435 156/18722 0.297088810200739 0.659426686517366 EGFR/FOLR1/BMP7/CALR/LMNA 5 GO:0000478 endonucleolytic cleavage involved in rRNA processing 1/435 15/18722 0.297258840546576 0.659426686517366 RPS21 1 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/435 15/18722 0.297258840546576 0.659426686517366 RPS21 1 GO:0002070 epithelial cell maturation 1/435 15/18722 0.297258840546576 0.659426686517366 AKR1B1 1 GO:0002836 positive regulation of response to tumor cell 1/435 15/18722 0.297258840546576 0.659426686517366 HSPD1 1 GO:0002839 positive regulation of immune response to tumor cell 1/435 15/18722 0.297258840546576 0.659426686517366 HSPD1 1 GO:0006089 lactate metabolic process 1/435 15/18722 0.297258840546576 0.659426686517366 PARK7 1 GO:0006098 pentose-phosphate shunt 1/435 15/18722 0.297258840546576 0.659426686517366 RPIA 1 GO:0006878 cellular copper ion homeostasis 1/435 15/18722 0.297258840546576 0.659426686517366 APP 1 GO:0007000 nucleolus organization 1/435 15/18722 0.297258840546576 0.659426686517366 RPS19 1 GO:0009083 branched-chain amino acid catabolic process 1/435 15/18722 0.297258840546576 0.659426686517366 ECHS1 1 GO:0009163 nucleoside biosynthetic process 1/435 15/18722 0.297258840546576 0.659426686517366 PNP 1 GO:0010273 detoxification of copper ion 1/435 15/18722 0.297258840546576 0.659426686517366 PARK7 1 GO:0018216 peptidyl-arginine methylation 1/435 15/18722 0.297258840546576 0.659426686517366 PRMT1 1 GO:0018410 C-terminal protein amino acid modification 1/435 15/18722 0.297258840546576 0.659426686517366 LCMT1 1 GO:0023035 CD40 signaling pathway 1/435 15/18722 0.297258840546576 0.659426686517366 PHB 1 GO:0032933 SREBP signaling pathway 1/435 15/18722 0.297258840546576 0.659426686517366 LPCAT3 1 GO:0033599 regulation of mammary gland epithelial cell proliferation 1/435 15/18722 0.297258840546576 0.659426686517366 CCND1 1 GO:0034404 nucleobase-containing small molecule biosynthetic process 1/435 15/18722 0.297258840546576 0.659426686517366 PNP 1 GO:0035435 phosphate ion transmembrane transport 1/435 15/18722 0.297258840546576 0.659426686517366 SLC25A3 1 GO:0035493 SNARE complex assembly 1/435 15/18722 0.297258840546576 0.659426686517366 VAMP8 1 GO:0036124 histone H3-K9 trimethylation 1/435 15/18722 0.297258840546576 0.659426686517366 LMNA 1 GO:0042074 cell migration involved in gastrulation 1/435 15/18722 0.297258840546576 0.659426686517366 AMOT 1 GO:0042182 ketone catabolic process 1/435 15/18722 0.297258840546576 0.659426686517366 PARK7 1 GO:0043508 negative regulation of JUN kinase activity 1/435 15/18722 0.297258840546576 0.659426686517366 GSTP1 1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 1/435 15/18722 0.297258840546576 0.659426686517366 MIF 1 GO:0044406 adhesion of symbiont to host 1/435 15/18722 0.297258840546576 0.659426686517366 HSP90AB1 1 GO:0045986 negative regulation of smooth muscle contraction 1/435 15/18722 0.297258840546576 0.659426686517366 SOD1 1 GO:0046459 short-chain fatty acid metabolic process 1/435 15/18722 0.297258840546576 0.659426686517366 ACSS1 1 GO:0050746 regulation of lipoprotein metabolic process 1/435 15/18722 0.297258840546576 0.659426686517366 DBI 1 GO:0051127 positive regulation of actin nucleation 1/435 15/18722 0.297258840546576 0.659426686517366 WASF2 1 GO:0051608 histamine transport 1/435 15/18722 0.297258840546576 0.659426686517366 VAMP8 1 GO:0051775 response to redox state 1/435 15/18722 0.297258840546576 0.659426686517366 ADH5 1 GO:0051938 L-glutamate import 1/435 15/18722 0.297258840546576 0.659426686517366 ARL6IP5 1 GO:0055012 ventricular cardiac muscle cell differentiation 1/435 15/18722 0.297258840546576 0.659426686517366 LMNA 1 GO:0060049 regulation of protein glycosylation 1/435 15/18722 0.297258840546576 0.659426686517366 TMEM59 1 GO:0060456 positive regulation of digestive system process 1/435 15/18722 0.297258840546576 0.659426686517366 LPCAT3 1 GO:0060766 negative regulation of androgen receptor signaling pathway 1/435 15/18722 0.297258840546576 0.659426686517366 PHB 1 GO:0070071 proton-transporting two-sector ATPase complex assembly 1/435 15/18722 0.297258840546576 0.659426686517366 ATP6V1B1 1 GO:0070131 positive regulation of mitochondrial translation 1/435 15/18722 0.297258840546576 0.659426686517366 C1QBP 1 GO:0070831 basement membrane assembly 1/435 15/18722 0.297258840546576 0.659426686517366 DAG1 1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum 1/435 15/18722 0.297258840546576 0.659426686517366 BCAP31 1 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus 1/435 15/18722 0.297258840546576 0.659426686517366 NPM1 1 GO:0072044 collecting duct development 1/435 15/18722 0.297258840546576 0.659426686517366 AKR1B1 1 GO:0072075 metanephric mesenchyme development 1/435 15/18722 0.297258840546576 0.659426686517366 BMP7 1 GO:0098712 L-glutamate import across plasma membrane 1/435 15/18722 0.297258840546576 0.659426686517366 ARL6IP5 1 GO:0099170 postsynaptic modulation of chemical synaptic transmission 1/435 15/18722 0.297258840546576 0.659426686517366 CDH1 1 GO:0140374 antiviral innate immune response 1/435 15/18722 0.297258840546576 0.659426686517366 PHB 1 GO:1901660 calcium ion export 1/435 15/18722 0.297258840546576 0.659426686517366 ATP2B1 1 GO:1903727 positive regulation of phospholipid metabolic process 1/435 15/18722 0.297258840546576 0.659426686517366 STOML2 1 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA 1/435 15/18722 0.297258840546576 0.659426686517366 LIN28B 1 GO:1904424 regulation of GTP binding 1/435 15/18722 0.297258840546576 0.659426686517366 MET 1 GO:1904874 positive regulation of telomerase RNA localization to Cajal body 1/435 15/18722 0.297258840546576 0.659426686517366 NHP2 1 GO:1905168 positive regulation of double-strand break repair via homologous recombination 1/435 15/18722 0.297258840546576 0.659426686517366 PARP1 1 GO:1905288 vascular associated smooth muscle cell apoptotic process 1/435 15/18722 0.297258840546576 0.659426686517366 DNMT1 1 GO:1905459 regulation of vascular associated smooth muscle cell apoptotic process 1/435 15/18722 0.297258840546576 0.659426686517366 DNMT1 1 GO:1990169 stress response to copper ion 1/435 15/18722 0.297258840546576 0.659426686517366 PARK7 1 GO:1990822 basic amino acid transmembrane transport 1/435 15/18722 0.297258840546576 0.659426686517366 SLC38A9 1 GO:2001028 positive regulation of endothelial cell chemotaxis 1/435 15/18722 0.297258840546576 0.659426686517366 MET 1 GO:2001138 regulation of phospholipid transport 1/435 15/18722 0.297258840546576 0.659426686517366 DBI 1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 3/435 82/18722 0.297309027264956 0.659426686517366 PARK7/LGALS3/BAD 3 GO:2001252 positive regulation of chromosome organization 3/435 82/18722 0.297309027264956 0.659426686517366 PKIB/DNMT1/SSBP1 3 GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 2/435 47/18722 0.298466817172758 0.659426686517366 MME/ADRB1 2 GO:0009261 ribonucleotide catabolic process 2/435 47/18722 0.298466817172758 0.659426686517366 PNP/NUDT4 2 GO:0010761 fibroblast migration 2/435 47/18722 0.298466817172758 0.659426686517366 PDLIM1/CLN3 2 GO:0016574 histone ubiquitination 2/435 47/18722 0.298466817172758 0.659426686517366 PARK7/DDB1 2 GO:0032008 positive regulation of TOR signaling 2/435 47/18722 0.298466817172758 0.659426686517366 LAMTOR5/SLC38A9 2 GO:0046677 response to antibiotic 2/435 47/18722 0.298466817172758 0.659426686517366 SOD1/RPL23 2 GO:0050798 activated T cell proliferation 2/435 47/18722 0.298466817172758 0.659426686517366 CD24/RPS3 2 GO:0050885 neuromuscular process controlling balance 2/435 47/18722 0.298466817172758 0.659426686517366 APP/CLN3 2 GO:0051489 regulation of filopodium assembly 2/435 47/18722 0.298466817172758 0.659426686517366 CLN3/RAB17 2 GO:0051972 regulation of telomerase activity 2/435 47/18722 0.298466817172758 0.659426686517366 PKIB/HSP90AB1 2 GO:0010906 regulation of glucose metabolic process 4/435 119/18722 0.299456672449721 0.660507275854818 PHLDA2/BAD/DDB1/LCMT1 4 GO:0030282 bone mineralization 4/435 119/18722 0.299456672449721 0.660507275854818 FBN2/BMP7/ATRAID/ATP2B1 4 GO:0031398 positive regulation of protein ubiquitination 4/435 119/18722 0.299456672449721 0.660507275854818 NPM1/SKP2/CAV1/PDCD6 4 GO:0007030 Golgi organization 5/435 157/18722 0.301615766726327 0.662321861150777 TMED4/TMED9/LMAN1/PDE4DIP/TMED1 5 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 8/435 273/18722 0.30258803216356 0.662321861150777 CLDN4/BSG/CDH1/DSC2/TENM3/CADM1/DSC3/CLDN7 8 GO:1901292 nucleoside phosphate catabolic process 3/435 83/18722 0.303674012072581 0.662321861150777 PNP/NUDT4/SMPDL3A 3 GO:0030218 erythrocyte differentiation 4/435 120/18722 0.304691619734513 0.662321861150777 RPS14/RPS19/TMEM14C/PRMT1 4 GO:0071674 mononuclear cell migration 6/435 196/18722 0.304975128398328 0.662321861150777 RPS19/APP/C1QBP/LGALS3/CALR/CD47 6 GO:0090276 regulation of peptide hormone secretion 6/435 196/18722 0.304975128398328 0.662321861150777 EGFR/GJA1/MPC2/HMGN3/BAD/PHPT1 6 GO:0002699 positive regulation of immune effector process 7/435 235/18722 0.306142119896039 0.662321861150777 VAMP8/RPS19/HSPD1/CD46/CADM1/CD55/PHB 7 GO:0045930 negative regulation of mitotic cell cycle 7/435 235/18722 0.306142119896039 0.662321861150777 EGFR/CDKN1C/BMP7/AURKAIP1/CTDSPL/CCND1/LCMT1 7 GO:0002673 regulation of acute inflammatory response 2/435 48/18722 0.307082915065565 0.662321861150777 GSTP1/PARK7 2 GO:0033628 regulation of cell adhesion mediated by integrin 2/435 48/18722 0.307082915065565 0.662321861150777 EFNA1/FERMT1 2 GO:0035036 sperm-egg recognition 2/435 48/18722 0.307082915065565 0.662321861150777 FOLR1/SPESP1 2 GO:0042908 xenobiotic transport 2/435 48/18722 0.307082915065565 0.662321861150777 SLC2A1/GJA1 2 GO:0043303 mast cell degranulation 2/435 48/18722 0.307082915065565 0.662321861150777 VAMP8/S100A13 2 GO:0048146 positive regulation of fibroblast proliferation 2/435 48/18722 0.307082915065565 0.662321861150777 ANXA2/MIF 2 GO:0061647 histone H3-K9 modification 2/435 48/18722 0.307082915065565 0.662321861150777 DNMT1/LMNA 2 GO:1905710 positive regulation of membrane permeability 2/435 48/18722 0.307082915065565 0.662321861150777 HEBP2/BNIP3 2 GO:0048762 mesenchymal cell differentiation 7/435 236/18722 0.309843524961482 0.662321861150777 NRP2/FOLR1/BMP7/EFNA1/DAG1/LAMA5/PDCD6 7 GO:0006112 energy reserve metabolic process 3/435 84/18722 0.31004499188232 0.662321861150777 PHLDA2/UGP2/AGL 3 GO:0010660 regulation of muscle cell apoptotic process 3/435 84/18722 0.31004499188232 0.662321861150777 BMP7/DNMT1/BNIP3 3 GO:0015844 monoamine transport 3/435 84/18722 0.31004499188232 0.662321861150777 SLC6A4/PARK7/LY6E 3 GO:0098586 cellular response to virus 3/435 84/18722 0.31004499188232 0.662321861150777 IFI6/C1QBP/PHB 3 GO:0035966 response to topologically incorrect protein 5/435 159/18722 0.31070122044998 0.662321861150777 HSPD1/HSPE1/HSP90AB1/CCND1/ERLEC1 5 GO:0051170 import into nucleus 5/435 159/18722 0.31070122044998 0.662321861150777 CDH1/RPL23/HSP90AB1/LMNA/FERMT1 5 GO:0019318 hexose metabolic process 7/435 237/18722 0.313553555478239 0.662321861150777 PHLDA2/DCXR/FUCA1/AKR1B1/BAD/DDB1/LCMT1 7 GO:0031334 positive regulation of protein-containing complex assembly 7/435 237/18722 0.313553555478239 0.662321861150777 MET/RPS3/PARK7/LGALS3/FERMT1/RHOC/WASF2 7 GO:0001845 phagolysosome assembly 1/435 16/18722 0.313599910967394 0.662321861150777 CLN3 1 GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin 1/435 16/18722 0.313599910967394 0.662321861150777 MME 1 GO:0002093 auditory receptor cell morphogenesis 1/435 16/18722 0.313599910967394 0.662321861150777 SOD1 1 GO:0002693 positive regulation of cellular extravasation 1/435 16/18722 0.313599910967394 0.662321861150777 CD47 1 GO:0003084 positive regulation of systemic arterial blood pressure 1/435 16/18722 0.313599910967394 0.662321861150777 NR2F2 1 GO:0005980 glycogen catabolic process 1/435 16/18722 0.313599910967394 0.662321861150777 AGL 1 GO:0006004 fucose metabolic process 1/435 16/18722 0.313599910967394 0.662321861150777 FUCA1 1 GO:0006740 NADPH regeneration 1/435 16/18722 0.313599910967394 0.662321861150777 RPIA 1 GO:0007635 chemosensory behavior 1/435 16/18722 0.313599910967394 0.662321861150777 ATP6V1B1 1 GO:0017014 protein nitrosylation 1/435 16/18722 0.313599910967394 0.662321861150777 ADH5 1 GO:0018119 peptidyl-cysteine S-nitrosylation 1/435 16/18722 0.313599910967394 0.662321861150777 ADH5 1 GO:0019081 viral translation 1/435 16/18722 0.313599910967394 0.662321861150777 EIF3G 1 GO:0019377 glycolipid catabolic process 1/435 16/18722 0.313599910967394 0.662321861150777 FUCA1 1 GO:0021783 preganglionic parasympathetic fiber development 1/435 16/18722 0.313599910967394 0.662321861150777 NRP2 1 GO:0030540 female genitalia development 1/435 16/18722 0.313599910967394 0.662321861150777 LRP2 1 GO:0032274 gonadotropin secretion 1/435 16/18722 0.313599910967394 0.662321861150777 GJA1 1 GO:0034116 positive regulation of heterotypic cell-cell adhesion 1/435 16/18722 0.313599910967394 0.662321861150777 BMP7 1 GO:0035751 regulation of lysosomal lumen pH 1/435 16/18722 0.313599910967394 0.662321861150777 CLN3 1 GO:0035864 response to potassium ion 1/435 16/18722 0.313599910967394 0.662321861150777 SOD1 1 GO:0045722 positive regulation of gluconeogenesis 1/435 16/18722 0.313599910967394 0.662321861150777 DDB1 1 GO:0048385 regulation of retinoic acid receptor signaling pathway 1/435 16/18722 0.313599910967394 0.662321861150777 CALR 1 GO:0051014 actin filament severing 1/435 16/18722 0.313599910967394 0.662321861150777 DSTN 1 GO:0060330 regulation of response to interferon-gamma 1/435 16/18722 0.313599910967394 0.662321861150777 HSP90AB1 1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway 1/435 16/18722 0.313599910967394 0.662321861150777 HSP90AB1 1 GO:0060572 morphogenesis of an epithelial bud 1/435 16/18722 0.313599910967394 0.662321861150777 BMP7 1 GO:0061548 ganglion development 1/435 16/18722 0.313599910967394 0.662321861150777 NRP2 1 GO:0070242 thymocyte apoptotic process 1/435 16/18722 0.313599910967394 0.662321861150777 EFNA1 1 GO:0070365 hepatocyte differentiation 1/435 16/18722 0.313599910967394 0.662321861150777 KRT18 1 GO:0071501 cellular response to sterol depletion 1/435 16/18722 0.313599910967394 0.662321861150777 LPCAT3 1 GO:0072109 glomerular mesangium development 1/435 16/18722 0.313599910967394 0.662321861150777 BMP7 1 GO:0072148 epithelial cell fate commitment 1/435 16/18722 0.313599910967394 0.662321861150777 NR2F2 1 GO:0090231 regulation of spindle checkpoint 1/435 16/18722 0.313599910967394 0.662321861150777 LCMT1 1 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint 1/435 16/18722 0.313599910967394 0.662321861150777 LCMT1 1 GO:0090336 positive regulation of brown fat cell differentiation 1/435 16/18722 0.313599910967394 0.662321861150777 BMP7 1 GO:0090520 sphingolipid mediated signaling pathway 1/435 16/18722 0.313599910967394 0.662321861150777 S1PR2 1 GO:0098969 neurotransmitter receptor transport to postsynaptic membrane 1/435 16/18722 0.313599910967394 0.662321861150777 NSG1 1 GO:0099010 modification of postsynaptic structure 1/435 16/18722 0.313599910967394 0.662321861150777 MYH10 1 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration 1/435 16/18722 0.313599910967394 0.662321861150777 ATP2B1 1 GO:0099633 protein localization to postsynaptic specialization membrane 1/435 16/18722 0.313599910967394 0.662321861150777 DAG1 1 GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane 1/435 16/18722 0.313599910967394 0.662321861150777 DAG1 1 GO:1901201 regulation of extracellular matrix assembly 1/435 16/18722 0.313599910967394 0.662321861150777 DAG1 1 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/435 16/18722 0.313599910967394 0.662321861150777 MIF 1 GO:1902570 protein localization to nucleolus 1/435 16/18722 0.313599910967394 0.662321861150777 NPM1 1 GO:1902931 negative regulation of alcohol biosynthetic process 1/435 16/18722 0.313599910967394 0.662321861150777 SOD1 1 GO:1903504 regulation of mitotic spindle checkpoint 1/435 16/18722 0.313599910967394 0.662321861150777 LCMT1 1 GO:2000232 regulation of rRNA processing 1/435 16/18722 0.313599910967394 0.662321861150777 TRMT112 1 GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 1/435 16/18722 0.313599910967394 0.662321861150777 PARK7 1 GO:1990266 neutrophil migration 4/435 122/18722 0.315189896790404 0.662321861150777 BSG/PPIB/C1QBP/LGALS3 4 GO:0090316 positive regulation of intracellular protein transport 5/435 160/18722 0.315258256796901 0.662321861150777 CDH1/BCAP31/HSP90AB1/PDCD5/FIS1 5 GO:0000959 mitochondrial RNA metabolic process 2/435 49/18722 0.315678299249524 0.662321861150777 SLIRP/TFAM 2 GO:0002279 mast cell activation involved in immune response 2/435 49/18722 0.315678299249524 0.662321861150777 VAMP8/S100A13 2 GO:0008038 neuron recognition 2/435 49/18722 0.315678299249524 0.662321861150777 BSG/APP 2 GO:0009395 phospholipid catabolic process 2/435 49/18722 0.315678299249524 0.662321861150777 IDH1/PRDX6 2 GO:0010823 negative regulation of mitochondrion organization 2/435 49/18722 0.315678299249524 0.662321861150777 LMNA/BNIP3 2 GO:0018198 peptidyl-cysteine modification 2/435 49/18722 0.315678299249524 0.662321861150777 ADH5/PARK7 2 GO:0030225 macrophage differentiation 2/435 49/18722 0.315678299249524 0.662321861150777 PARP1/APP 2 GO:0030857 negative regulation of epithelial cell differentiation 2/435 49/18722 0.315678299249524 0.662321861150777 CCND1/CAV1 2 GO:0034332 adherens junction organization 2/435 49/18722 0.315678299249524 0.662321861150777 CDH1/DSP 2 GO:0043330 response to exogenous dsRNA 2/435 49/18722 0.315678299249524 0.662321861150777 COLEC12/CAV1 2 GO:0048168 regulation of neuronal synaptic plasticity 2/435 49/18722 0.315678299249524 0.662321861150777 APP/CLN3 2 GO:0060964 regulation of gene silencing by miRNA 2/435 49/18722 0.315678299249524 0.662321861150777 EGFR/LIN28B 2 GO:0070849 response to epidermal growth factor 2/435 49/18722 0.315678299249524 0.662321861150777 GSTP1/EGFR 2 GO:0086009 membrane repolarization 2/435 49/18722 0.315678299249524 0.662321861150777 GJA5/CAV1 2 GO:1901799 negative regulation of proteasomal protein catabolic process 2/435 49/18722 0.315678299249524 0.662321861150777 HSP90AB1/PARK7 2 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 2/435 49/18722 0.315678299249524 0.662321861150777 PARK7/LGALS3 2 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 2/435 49/18722 0.315678299249524 0.662321861150777 DNMT1/GJA1 2 GO:1904894 positive regulation of receptor signaling pathway via STAT 2/435 49/18722 0.315678299249524 0.662321861150777 IL10RB/AKR1B1 2 GO:0019693 ribose phosphate metabolic process 11/435 396/18722 0.315854598321179 0.662340564683045 PARP1/ACSS1/APP/PNP/TECR/NUDT4/MPC2/BAD/STOML2/TPST2/RPIA 11 GO:0110053 regulation of actin filament organization 8/435 277/18722 0.316283426725629 0.662823873637177 MET/S100A10/DSTN/TACSTD2/KANK4/RHOC/WASF2/CD47 8 GO:0001656 metanephros development 3/435 85/18722 0.316420090295837 0.662823873637177 BMP7/FBN1/AKR1B1 3 GO:0009101 glycoprotein biosynthetic process 9/435 317/18722 0.317834573170471 0.665082710753862 GALNT11/TUSC3/EXTL2/DDOST/RPN2/OSTC/TMEM59/CHPF/TMEM258 9 GO:0010506 regulation of autophagy 9/435 317/18722 0.317834573170471 0.665082710753862 MET/CLN3/CISD1/PARK7/ATP6V1B1/BAD/TMEM59/SCOC/BNIP3 9 GO:0071482 cellular response to light stimulus 4/435 123/18722 0.320451036479377 0.66841427061504 PARP1/MME/NPM1/DDB1 4 GO:0002791 regulation of peptide secretion 6/435 200/18722 0.32126671725674 0.66841427061504 EGFR/GJA1/MPC2/HMGN3/BAD/PHPT1 6 GO:0072522 purine-containing compound biosynthetic process 6/435 200/18722 0.32126671725674 0.66841427061504 PARP1/ACSS1/PNP/TECR/MPC2/STOML2 6 GO:0015908 fatty acid transport 3/435 86/18722 0.32279747190202 0.66841427061504 SLC2A1/SLC27A2/FIS1 3 GO:0022406 membrane docking 3/435 86/18722 0.32279747190202 0.66841427061504 VAMP8/CLN3/SNX3 3 GO:0002448 mast cell mediated immunity 2/435 50/18722 0.324249286959336 0.66841427061504 VAMP8/S100A13 2 GO:1902930 regulation of alcohol biosynthetic process 2/435 50/18722 0.324249286959336 0.66841427061504 SOD1/LPCAT3 2 GO:1903747 regulation of establishment of protein localization to mitochondrion 2/435 50/18722 0.324249286959336 0.66841427061504 PDCD5/LMAN1 2 GO:0051100 negative regulation of binding 5/435 162/18722 0.324397332617397 0.66841427061504 LRPAP1/PARK7/MSX2/ZNF593/CAV1 5 GO:0051494 negative regulation of cytoskeleton organization 5/435 162/18722 0.324397332617397 0.66841427061504 MET/TACSTD2/NPM1/KANK4/WASF2 5 GO:0051054 positive regulation of DNA metabolic process 6/435 201/18722 0.32536016670816 0.66841427061504 EGFR/PKIB/ANXA3/PARP1/HSP90AB1/RPS3 6 GO:0010976 positive regulation of neuron projection development 5/435 163/18722 0.328977941273673 0.66841427061504 SERPINF1/ITGA6/BMP7/TENM3/SNX3 5 GO:0019915 lipid storage 3/435 87/18722 0.329175342376261 0.66841427061504 MEST/HILPDA/CAV1 3 GO:1901606 alpha-amino acid catabolic process 3/435 87/18722 0.329175342376261 0.66841427061504 GCSH/GLDC/CDO1 3 GO:0007015 actin filament organization 12/435 441/18722 0.329437680214565 0.66841427061504 MET/PDLIM1/HSP90B1/S100A10/DSTN/TACSTD2/MSRB2/KANK4/RHOC/WASF2/ITGB5/CD47 12 GO:0032388 positive regulation of intracellular transport 6/435 202/18722 0.329460805966656 0.66841427061504 ANXA2/CDH1/BCAP31/HSP90AB1/PDCD5/FIS1 6 GO:0090087 regulation of peptide transport 6/435 202/18722 0.329460805966656 0.66841427061504 EGFR/GJA1/MPC2/HMGN3/BAD/PHPT1 6 GO:0003184 pulmonary valve morphogenesis 1/435 17/18722 0.329561850384115 0.66841427061504 GJA5 1 GO:0006390 mitochondrial transcription 1/435 17/18722 0.329561850384115 0.66841427061504 TFAM 1 GO:0006577 amino-acid betaine metabolic process 1/435 17/18722 0.329561850384115 0.66841427061504 ALDH7A1 1 GO:0009151 purine deoxyribonucleotide metabolic process 1/435 17/18722 0.329561850384115 0.66841427061504 PNP 1 GO:0009251 glucan catabolic process 1/435 17/18722 0.329561850384115 0.66841427061504 AGL 1 GO:0010224 response to UV-B 1/435 17/18722 0.329561850384115 0.66841427061504 MME 1 GO:0010470 regulation of gastrulation 1/435 17/18722 0.329561850384115 0.66841427061504 DAG1 1 GO:0010612 regulation of cardiac muscle adaptation 1/435 17/18722 0.329561850384115 0.66841427061504 LMNA 1 GO:0020027 hemoglobin metabolic process 1/435 17/18722 0.329561850384115 0.66841427061504 PRMT1 1 GO:0021924 cell proliferation in external granule layer 1/435 17/18722 0.329561850384115 0.66841427061504 SLC6A4 1 GO:0021930 cerebellar granule cell precursor proliferation 1/435 17/18722 0.329561850384115 0.66841427061504 SLC6A4 1 GO:0030322 stabilization of membrane potential 1/435 17/18722 0.329561850384115 0.66841427061504 KCNN4 1 GO:0030903 notochord development 1/435 17/18722 0.329561850384115 0.66841427061504 EFNA1 1 GO:0031445 regulation of heterochromatin assembly 1/435 17/18722 0.329561850384115 0.66841427061504 DNMT1 1 GO:0033623 regulation of integrin activation 1/435 17/18722 0.329561850384115 0.66841427061504 FERMT1 1 GO:0035518 histone H2A monoubiquitination 1/435 17/18722 0.329561850384115 0.66841427061504 DDB1 1 GO:0035855 megakaryocyte development 1/435 17/18722 0.329561850384115 0.66841427061504 WASF2 1 GO:0036166 phenotypic switching 1/435 17/18722 0.329561850384115 0.66841427061504 DNMT1 1 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 1/435 17/18722 0.329561850384115 0.66841427061504 CAV1 1 GO:0043649 dicarboxylic acid catabolic process 1/435 17/18722 0.329561850384115 0.66841427061504 QPRT 1 GO:0045591 positive regulation of regulatory T cell differentiation 1/435 17/18722 0.329561850384115 0.66841427061504 CD46 1 GO:0048532 anatomical structure arrangement 1/435 17/18722 0.329561850384115 0.66841427061504 NRP2 1 GO:0051797 regulation of hair follicle development 1/435 17/18722 0.329561850384115 0.66841427061504 FERMT1 1 GO:0055064 chloride ion homeostasis 1/435 17/18722 0.329561850384115 0.66841427061504 ATP6V1B1 1 GO:0055083 monovalent inorganic anion homeostasis 1/435 17/18722 0.329561850384115 0.66841427061504 ATP6V1B1 1 GO:0060263 regulation of respiratory burst 1/435 17/18722 0.329561850384115 0.66841427061504 RPS19 1 GO:0060977 coronary vasculature morphogenesis 1/435 17/18722 0.329561850384115 0.66841427061504 LRP2 1 GO:0070593 dendrite self-avoidance 1/435 17/18722 0.329561850384115 0.66841427061504 BSG 1 GO:0071816 tail-anchored membrane protein insertion into ER membrane 1/435 17/18722 0.329561850384115 0.66841427061504 EMC7 1 GO:0072673 lamellipodium morphogenesis 1/435 17/18722 0.329561850384115 0.66841427061504 WASF2 1 GO:0090494 dopamine uptake 1/435 17/18722 0.329561850384115 0.66841427061504 PARK7 1 GO:0090713 immunological memory process 1/435 17/18722 0.329561850384115 0.66841427061504 CD46 1 GO:0097067 cellular response to thyroid hormone stimulus 1/435 17/18722 0.329561850384115 0.66841427061504 CTSL 1 GO:0120261 regulation of heterochromatin organization 1/435 17/18722 0.329561850384115 0.66841427061504 DNMT1 1 GO:1901550 regulation of endothelial cell development 1/435 17/18722 0.329561850384115 0.66841427061504 S1PR2 1 GO:1903140 regulation of establishment of endothelial barrier 1/435 17/18722 0.329561850384115 0.66841427061504 S1PR2 1 GO:1903242 regulation of cardiac muscle hypertrophy in response to stress 1/435 17/18722 0.329561850384115 0.66841427061504 LMNA 1 GO:1903358 regulation of Golgi organization 1/435 17/18722 0.329561850384115 0.66841427061504 PDE4DIP 1 GO:1903540 establishment of protein localization to postsynaptic membrane 1/435 17/18722 0.329561850384115 0.66841427061504 NSG1 1 GO:1903830 magnesium ion transmembrane transport 1/435 17/18722 0.329561850384115 0.66841427061504 TUSC3 1 GO:1904355 positive regulation of telomere capping 1/435 17/18722 0.329561850384115 0.66841427061504 PKIB 1 GO:2000696 regulation of epithelial cell differentiation involved in kidney development 1/435 17/18722 0.329561850384115 0.66841427061504 CD24 1 GO:2000811 negative regulation of anoikis 1/435 17/18722 0.329561850384115 0.66841427061504 CAV1 1 GO:0018210 peptidyl-threonine modification 4/435 125/18722 0.330991942073672 0.670627298917317 GALNT11/BMP7/APP/S1PR2 4 GO:0071621 granulocyte chemotaxis 4/435 125/18722 0.330991942073672 0.670627298917317 BSG/PPIB/C1QBP/LGALS3 4 GO:0006636 unsaturated fatty acid biosynthetic process 2/435 51/18722 0.332792376953262 0.672897003374583 DEGS1/MIF 2 GO:0010656 negative regulation of muscle cell apoptotic process 2/435 51/18722 0.332792376953262 0.672897003374583 BMP7/DNMT1 2 GO:0021872 forebrain generation of neurons 2/435 51/18722 0.332792376953262 0.672897003374583 NRP2/UQCRQ 2 GO:0051339 regulation of lyase activity 2/435 51/18722 0.332792376953262 0.672897003374583 PARK7/PHPT1 2 GO:0050792 regulation of viral process 5/435 164/18722 0.333564985704042 0.674114733621499 P4HB/HACD3/LY6E/SNX3/DDB1 5 GO:1901657 glycosyl compound metabolic process 3/435 88/18722 0.335551948530467 0.676124823425485 PNP/FUCA1/AKR1B1 3 GO:0046661 male sex differentiation 5/435 165/18722 0.338157764557882 0.676124823425485 ADGRG1/LRP2/PRDX4/EIF2S2/CCND1 5 GO:0050796 regulation of insulin secretion 5/435 165/18722 0.338157764557882 0.676124823425485 GJA1/MPC2/HMGN3/BAD/PHPT1 5 GO:0071772 response to BMP 5/435 165/18722 0.338157764557882 0.676124823425485 SPINT2/SPINT1/BMP7/LRP2/FBN1 5 GO:0071773 cellular response to BMP stimulus 5/435 165/18722 0.338157764557882 0.676124823425485 SPINT2/SPINT1/BMP7/LRP2/FBN1 5 GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 2/435 52/18722 0.341304243099447 0.676124823425485 ERGIC3/KDELR1 2 GO:0010662 regulation of striated muscle cell apoptotic process 2/435 52/18722 0.341304243099447 0.676124823425485 BMP7/BNIP3 2 GO:0030514 negative regulation of BMP signaling pathway 2/435 52/18722 0.341304243099447 0.676124823425485 LRP2/FBN1 2 GO:0035196 production of miRNAs involved in gene silencing by miRNA 2/435 52/18722 0.341304243099447 0.676124823425485 EGFR/LIN28B 2 GO:0043392 negative regulation of DNA binding 2/435 52/18722 0.341304243099447 0.676124823425485 MSX2/ZNF593 2 GO:0060147 regulation of posttranscriptional gene silencing 2/435 52/18722 0.341304243099447 0.676124823425485 EGFR/LIN28B 2 GO:0072523 purine-containing compound catabolic process 2/435 52/18722 0.341304243099447 0.676124823425485 PNP/NUDT4 2 GO:0010657 muscle cell apoptotic process 3/435 89/18722 0.341925578316516 0.676124823425485 BMP7/DNMT1/BNIP3 3 GO:0014910 regulation of smooth muscle cell migration 3/435 89/18722 0.341925578316516 0.676124823425485 GSTP1/S100A11/S1PR2 3 GO:0043112 receptor metabolic process 5/435 166/18722 0.342755582486925 0.676124823425485 ANXA2/LRPAP1/RNF43/NSG1/CAV1 5 GO:1902904 negative regulation of supramolecular fiber organization 5/435 166/18722 0.342755582486925 0.676124823425485 MET/TACSTD2/KANK4/PFDN1/WASF2 5 GO:0001522 pseudouridine synthesis 1/435 18/18722 0.345153435258903 0.676124823425485 NHP2 1 GO:0002283 neutrophil activation involved in immune response 1/435 18/18722 0.345153435258903 0.676124823425485 ANXA3 1 GO:0002501 peptide antigen assembly with MHC protein complex 1/435 18/18722 0.345153435258903 0.676124823425485 CALR 1 GO:0002544 chronic inflammatory response 1/435 18/18722 0.345153435258903 0.676124823425485 GJA1 1 GO:0003128 heart field specification 1/435 18/18722 0.345153435258903 0.676124823425485 LRP2 1 GO:0006103 2-oxoglutarate metabolic process 1/435 18/18722 0.345153435258903 0.676124823425485 IDH1 1 GO:0006337 nucleosome disassembly 1/435 18/18722 0.345153435258903 0.676124823425485 HMGA1 1 GO:0006595 polyamine metabolic process 1/435 18/18722 0.345153435258903 0.676124823425485 SMS 1 GO:0006991 response to sterol depletion 1/435 18/18722 0.345153435258903 0.676124823425485 LPCAT3 1 GO:0009125 nucleoside monophosphate catabolic process 1/435 18/18722 0.345153435258903 0.676124823425485 PNP 1 GO:0010663 positive regulation of striated muscle cell apoptotic process 1/435 18/18722 0.345153435258903 0.676124823425485 BNIP3 1 GO:0010666 positive regulation of cardiac muscle cell apoptotic process 1/435 18/18722 0.345153435258903 0.676124823425485 BNIP3 1 GO:0010985 negative regulation of lipoprotein particle clearance 1/435 18/18722 0.345153435258903 0.676124823425485 LRPAP1 1 GO:0015693 magnesium ion transport 1/435 18/18722 0.345153435258903 0.676124823425485 TUSC3 1 GO:0021534 cell proliferation in hindbrain 1/435 18/18722 0.345153435258903 0.676124823425485 SLC6A4 1 GO:0030206 chondroitin sulfate biosynthetic process 1/435 18/18722 0.345153435258903 0.676124823425485 CHPF 1 GO:0030299 intestinal cholesterol absorption 1/435 18/18722 0.345153435258903 0.676124823425485 LPCAT3 1 GO:0031643 positive regulation of myelination 1/435 18/18722 0.345153435258903 0.676124823425485 DAG1 1 GO:0031649 heat generation 1/435 18/18722 0.345153435258903 0.676124823425485 ADRB1 1 GO:0032095 regulation of response to food 1/435 18/18722 0.345153435258903 0.676124823425485 NENF 1 GO:0032769 negative regulation of monooxygenase activity 1/435 18/18722 0.345153435258903 0.676124823425485 CAV1 1 GO:0042136 neurotransmitter biosynthetic process 1/435 18/18722 0.345153435258903 0.676124823425485 SLC6A4 1 GO:0044247 cellular polysaccharide catabolic process 1/435 18/18722 0.345153435258903 0.676124823425485 AGL 1 GO:0045116 protein neddylation 1/435 18/18722 0.345153435258903 0.676124823425485 NEDD8 1 GO:0045187 regulation of circadian sleep/wake cycle, sleep 1/435 18/18722 0.345153435258903 0.676124823425485 ADRB1 1 GO:0045653 negative regulation of megakaryocyte differentiation 1/435 18/18722 0.345153435258903 0.676124823425485 PRMT1 1 GO:0046040 IMP metabolic process 1/435 18/18722 0.345153435258903 0.676124823425485 PNP 1 GO:0048486 parasympathetic nervous system development 1/435 18/18722 0.345153435258903 0.676124823425485 NRP2 1 GO:0050665 hydrogen peroxide biosynthetic process 1/435 18/18722 0.345153435258903 0.676124823425485 SOD1 1 GO:0055070 copper ion homeostasis 1/435 18/18722 0.345153435258903 0.676124823425485 APP 1 GO:0060391 positive regulation of SMAD protein signal transduction 1/435 18/18722 0.345153435258903 0.676124823425485 PARP1 1 GO:0060546 negative regulation of necroptotic process 1/435 18/18722 0.345153435258903 0.676124823425485 CAV1 1 GO:0060749 mammary gland alveolus development 1/435 18/18722 0.345153435258903 0.676124823425485 CCND1 1 GO:0061377 mammary gland lobule development 1/435 18/18722 0.345153435258903 0.676124823425485 CCND1 1 GO:0061484 hematopoietic stem cell homeostasis 1/435 18/18722 0.345153435258903 0.676124823425485 ADGRG1 1 GO:0061687 detoxification of inorganic compound 1/435 18/18722 0.345153435258903 0.676124823425485 PARK7 1 GO:0071071 regulation of phospholipid biosynthetic process 1/435 18/18722 0.345153435258903 0.676124823425485 IDH1 1 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis 1/435 18/18722 0.345153435258903 0.676124823425485 MAGED1 1 GO:0090493 catecholamine uptake 1/435 18/18722 0.345153435258903 0.676124823425485 PARK7 1 GO:0097094 craniofacial suture morphogenesis 1/435 18/18722 0.345153435258903 0.676124823425485 MSX2 1 GO:0098877 neurotransmitter receptor transport to plasma membrane 1/435 18/18722 0.345153435258903 0.676124823425485 NSG1 1 GO:1900006 positive regulation of dendrite development 1/435 18/18722 0.345153435258903 0.676124823425485 BMP7 1 GO:1902001 fatty acid transmembrane transport 1/435 18/18722 0.345153435258903 0.676124823425485 SLC2A1 1 GO:1902683 regulation of receptor localization to synapse 1/435 18/18722 0.345153435258903 0.676124823425485 DAG1 1 GO:1904872 regulation of telomerase RNA localization to Cajal body 1/435 18/18722 0.345153435258903 0.676124823425485 NHP2 1 GO:2000641 regulation of early endosome to late endosome transport 1/435 18/18722 0.345153435258903 0.676124823425485 SNX3 1 GO:0033865 nucleoside bisphosphate metabolic process 4/435 128/18722 0.346834150669106 0.678074473417813 ACSS1/TECR/MPC2/TPST2 4 GO:0033875 ribonucleoside bisphosphate metabolic process 4/435 128/18722 0.346834150669106 0.678074473417813 ACSS1/TECR/MPC2/TPST2 4 GO:0034032 purine nucleoside bisphosphate metabolic process 4/435 128/18722 0.346834150669106 0.678074473417813 ACSS1/TECR/MPC2/TPST2 4 GO:0035303 regulation of dephosphorylation 4/435 128/18722 0.346834150669106 0.678074473417813 HSP90B1/HSP90AB1/SLC39A10/LGALS3 4 GO:0031668 cellular response to extracellular stimulus 7/435 246/18722 0.34726728267962 0.678427748325614 GSTP1/SLC2A1/COMT/FOLR1/ATP2B1/SKP2/TXN2 7 GO:0007254 JNK cascade 5/435 167/18722 0.347357750343112 0.678427748325614 GSTP1/EGFR/DUSP9/APP/HACD3 5 GO:0034109 homotypic cell-cell adhesion 3/435 90/18722 0.348294560785818 0.679921843625792 DSP/GNAS/DSC2 3 GO:0009615 response to virus 10/435 367/18722 0.349166274396235 0.680140687141878 IFI6/VAMP8/IL10RB/C1QBP/HMGA1/AP1S1/PHB/LAMTOR5/SKP2/BNIP3 10 GO:0009117 nucleotide metabolic process 13/435 489/18722 0.34960277065911 0.680140687141878 QPRT/PARP1/ACSS1/APP/PNP/PARK7/TECR/NUDT4/MPC2/BAD/REXO2/STOML2/TPST2 13 GO:0002707 negative regulation of lymphocyte mediated immunity 2/435 53/18722 0.349781728161163 0.680140687141878 CD46/CD55 2 GO:0016925 protein sumoylation 2/435 53/18722 0.349781728161163 0.680140687141878 PARK7/CBX4 2 GO:0050819 negative regulation of coagulation 2/435 53/18722 0.349781728161163 0.680140687141878 ANXA2/ANXA5 2 GO:0060966 regulation of gene silencing by RNA 2/435 53/18722 0.349781728161163 0.680140687141878 EGFR/LIN28B 2 GO:0071320 cellular response to cAMP 2/435 53/18722 0.349781728161163 0.680140687141878 APP/ASS1 2 GO:2000772 regulation of cellular senescence 2/435 53/18722 0.349781728161163 0.680140687141878 HMGA1/YPEL3 2 GO:0050679 positive regulation of epithelial cell proliferation 6/435 207/18722 0.35005404811549 0.680335888208741 EGFR/NRP2/MYDGF/BAD/CCND1/PDCD6 6 GO:0007517 muscle organ development 9/435 327/18722 0.35030393614279 0.68048732219785 DSP/LRP2/NR2F2/DAG1/LY6E/ASS1/EID2/LAMA5/CAV1 9 GO:0009150 purine ribonucleotide metabolic process 10/435 368/18722 0.352253028213387 0.682640726709328 PARP1/ACSS1/APP/PNP/TECR/NUDT4/MPC2/BAD/STOML2/TPST2 10 GO:0002275 myeloid cell activation involved in immune response 3/435 91/18722 0.354657266007477 0.682640726709328 VAMP8/ANXA3/S100A13 3 GO:0045582 positive regulation of T cell differentiation 3/435 91/18722 0.354657266007477 0.682640726709328 PNP/BAD/CD46 3 GO:0060191 regulation of lipase activity 3/435 91/18722 0.354657266007477 0.682640726709328 EGFR/PHB/RHOC 3 GO:0009152 purine ribonucleotide biosynthetic process 5/435 169/18722 0.356572411376464 0.682640726709328 PARP1/ACSS1/TECR/MPC2/STOML2 5 GO:0006352 DNA-templated transcription, initiation 4/435 130/18722 0.357404300687651 0.682640726709328 GTF2H5/GTF2A2/POLR2I/TFAM 4 GO:0042476 odontogenesis 4/435 130/18722 0.357404300687651 0.682640726709328 PERP/BSG/BMP7/LAMA5 4 GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2/435 54/18722 0.358221837775239 0.682640726709328 CD46/CD55 2 GO:0007215 glutamate receptor signaling pathway 2/435 54/18722 0.358221837775239 0.682640726709328 APP/CLN3 2 GO:0030520 intracellular estrogen receptor signaling pathway 2/435 54/18722 0.358221837775239 0.682640726709328 PARP1/SKP2 2 GO:0031050 dsRNA processing 2/435 54/18722 0.358221837775239 0.682640726709328 EGFR/LIN28B 2 GO:0070918 production of small RNA involved in gene silencing by RNA 2/435 54/18722 0.358221837775239 0.682640726709328 EGFR/LIN28B 2 GO:0072348 sulfur compound transport 2/435 54/18722 0.358221837775239 0.682640726709328 GJA1/SLC13A3 2 GO:2000179 positive regulation of neural precursor cell proliferation 2/435 54/18722 0.358221837775239 0.682640726709328 ADGRG1/LRP2 2 GO:0046883 regulation of hormone secretion 7/435 249/18722 0.358604308377419 0.682640726709328 EGFR/VAMP8/GJA1/MPC2/HMGN3/BAD/PHPT1 7 GO:0003012 muscle system process 12/435 452/18722 0.360050010836405 0.682640726709328 SOD1/DSP/PARP1/GJA1/GJA5/DSC2/DAG1/LMNA/ASPH/SSPN/ATP2B1/CAV1 12 GO:0002396 MHC protein complex assembly 1/435 19/18722 0.360383239346926 0.682640726709328 CALR 1 GO:0002902 regulation of B cell apoptotic process 1/435 19/18722 0.360383239346926 0.682640726709328 SLC39A10 1 GO:0003085 negative regulation of systemic arterial blood pressure 1/435 19/18722 0.360383239346926 0.682640726709328 ADRB1 1 GO:0006007 glucose catabolic process 1/435 19/18722 0.360383239346926 0.682640726709328 BAD 1 GO:0006044 N-acetylglucosamine metabolic process 1/435 19/18722 0.360383239346926 0.682640726709328 EXTL2 1 GO:0009081 branched-chain amino acid metabolic process 1/435 19/18722 0.360383239346926 0.682640726709328 ECHS1 1 GO:0010738 regulation of protein kinase A signaling 1/435 19/18722 0.360383239346926 0.682640726709328 MIF 1 GO:0030011 maintenance of cell polarity 1/435 19/18722 0.360383239346926 0.682640726709328 PDLIM1 1 GO:0032026 response to magnesium ion 1/435 19/18722 0.360383239346926 0.682640726709328 CCND1 1 GO:0032695 negative regulation of interleukin-12 production 1/435 19/18722 0.360383239346926 0.682640726709328 C1QBP 1 GO:0035313 wound healing, spreading of epidermal cells 1/435 19/18722 0.360383239346926 0.682640726709328 FERMT1 1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process 1/435 19/18722 0.360383239346926 0.682640726709328 TECR 1 GO:0042776 mitochondrial ATP synthesis coupled proton transport 1/435 19/18722 0.360383239346926 0.682640726709328 STOML2 1 GO:0044003 modulation by symbiont of host process 1/435 19/18722 0.360383239346926 0.682640726709328 DAG1 1 GO:0045019 negative regulation of nitric oxide biosynthetic process 1/435 19/18722 0.360383239346926 0.682640726709328 CAV1 1 GO:0045780 positive regulation of bone resorption 1/435 19/18722 0.360383239346926 0.682640726709328 EGFR 1 GO:0045821 positive regulation of glycolytic process 1/435 19/18722 0.360383239346926 0.682640726709328 APP 1 GO:0046716 muscle cell cellular homeostasis 1/435 19/18722 0.360383239346926 0.682640726709328 SOD1 1 GO:0048245 eosinophil chemotaxis 1/435 19/18722 0.360383239346926 0.682640726709328 LGALS3 1 GO:0051546 keratinocyte migration 1/435 19/18722 0.360383239346926 0.682640726709328 FERMT1 1 GO:0051571 positive regulation of histone H3-K4 methylation 1/435 19/18722 0.360383239346926 0.682640726709328 DNMT1 1 GO:0060039 pericardium development 1/435 19/18722 0.360383239346926 0.682640726709328 BMP7 1 GO:0062099 negative regulation of programmed necrotic cell death 1/435 19/18722 0.360383239346926 0.682640726709328 CAV1 1 GO:0070233 negative regulation of T cell apoptotic process 1/435 19/18722 0.360383239346926 0.682640726709328 EFNA1 1 GO:0072074 kidney mesenchyme development 1/435 19/18722 0.360383239346926 0.682640726709328 BMP7 1 GO:0090670 RNA localization to Cajal body 1/435 19/18722 0.360383239346926 0.682640726709328 NHP2 1 GO:0090671 telomerase RNA localization to Cajal body 1/435 19/18722 0.360383239346926 0.682640726709328 NHP2 1 GO:0090672 telomerase RNA localization 1/435 19/18722 0.360383239346926 0.682640726709328 NHP2 1 GO:0090685 RNA localization to nucleus 1/435 19/18722 0.360383239346926 0.682640726709328 NHP2 1 GO:0097501 stress response to metal ion 1/435 19/18722 0.360383239346926 0.682640726709328 PARK7 1 GO:1900221 regulation of amyloid-beta clearance 1/435 19/18722 0.360383239346926 0.682640726709328 LRPAP1 1 GO:1901659 glycosyl compound biosynthetic process 1/435 19/18722 0.360383239346926 0.682640726709328 PNP 1 GO:1901881 positive regulation of protein depolymerization 1/435 19/18722 0.360383239346926 0.682640726709328 DSTN 1 GO:1903204 negative regulation of oxidative stress-induced neuron death 1/435 19/18722 0.360383239346926 0.682640726709328 PARK7 1 GO:1904406 negative regulation of nitric oxide metabolic process 1/435 19/18722 0.360383239346926 0.682640726709328 CAV1 1 GO:2000738 positive regulation of stem cell differentiation 1/435 19/18722 0.360383239346926 0.682640726709328 TACSTD2 1 GO:1903351 cellular response to dopamine 3/435 92/18722 0.361012104947492 0.683504736496281 TGM2/GNAS/NSG1 3 GO:0002685 regulation of leukocyte migration 6/435 210/18722 0.362463983388087 0.68569537183384 APP/C1QBP/LGALS3/CALR/MIF/CD47 6 GO:0000723 telomere maintenance 4/435 131/18722 0.362689010171399 0.68569537183384 PKIB/PARP1/HSP90AB1/NHP2 4 GO:0006612 protein targeting to membrane 4/435 131/18722 0.362689010171399 0.68569537183384 SRP14/FIS1/SIL1/SSR2 4 GO:0046890 regulation of lipid biosynthetic process 5/435 171/18722 0.365796365490834 0.687773223261085 SOD1/IDH1/ACADVL/ORMDL1/LPCAT3 5 GO:0030100 regulation of endocytosis 6/435 211/18722 0.366606667296285 0.687773223261085 ANXA2/LRPAP1/CLN3/LGALS3/CAV1/RAB17 6 GO:0050807 regulation of synapse organization 6/435 211/18722 0.366606667296285 0.687773223261085 NRP2/APP/CLN3/EFNA1/DAG1/RAB17 6 GO:0003179 heart valve morphogenesis 2/435 55/18722 0.36662173461807 0.687773223261085 GJA5/EFNA1 2 GO:0006360 transcription by RNA polymerase I 2/435 55/18722 0.36662173461807 0.687773223261085 POLR2L/GTF2H5 2 GO:0031113 regulation of microtubule polymerization 2/435 55/18722 0.36662173461807 0.687773223261085 MET/RPS3 2 GO:0051898 negative regulation of protein kinase B signaling 2/435 55/18722 0.36662173461807 0.687773223261085 DAG1/PDCD6 2 GO:0061098 positive regulation of protein tyrosine kinase activity 2/435 55/18722 0.36662173461807 0.687773223261085 CD24/EFNA1 2 GO:1905517 macrophage migration 2/435 55/18722 0.36662173461807 0.687773223261085 LGALS3/MIF 2 GO:0090398 cellular senescence 3/435 93/18722 0.367357529311301 0.687773223261085 HMGA1/YPEL3/CALR 3 GO:0097306 cellular response to alcohol 3/435 93/18722 0.367357529311301 0.687773223261085 CDH1/DAG1/ATP2B1 3 GO:1901992 positive regulation of mitotic cell cycle phase transition 3/435 93/18722 0.367357529311301 0.687773223261085 EGFR/APP/CCND1 3 GO:1903350 response to dopamine 3/435 93/18722 0.367357529311301 0.687773223261085 TGM2/GNAS/NSG1 3 GO:0035264 multicellular organism growth 4/435 132/18722 0.367972191748446 0.687773223261085 SOD1/PPIB/APP/ADRB1 4 GO:0002221 pattern recognition receptor signaling pathway 5/435 172/18722 0.370410175610217 0.687773223261085 COLEC12/HSPD1/C1QBP/PHB/CAV1 5 GO:0007219 Notch signaling pathway 5/435 172/18722 0.370410175610217 0.687773223261085 PERP/GALNT11/BMP7/APP/CD46 5 GO:0032091 negative regulation of protein binding 3/435 94/18722 0.373692031351889 0.687773223261085 LRPAP1/PARK7/CAV1 3 GO:1990830 cellular response to leukemia inhibitory factor 3/435 94/18722 0.373692031351889 0.687773223261085 RPS16/NRP2/PCOLCE2 3 GO:0008654 phospholipid biosynthetic process 7/435 253/18722 0.373768945597216 0.687773223261085 ISYNA1/TMEM150A/CLN3/IDH1/PISD/PYURF/LPCAT3 7 GO:0051651 maintenance of location in cell 6/435 213/18722 0.374898191885128 0.687773223261085 HSP90B1/GJA1/PARK7/CALR/KDELR1/CAV1 6 GO:0002711 positive regulation of T cell mediated immunity 2/435 56/18722 0.374978732753787 0.687773223261085 HSPD1/CD55 2 GO:0010332 response to gamma radiation 2/435 56/18722 0.374978732753787 0.687773223261085 PARP1/GTF2H5 2 GO:0010518 positive regulation of phospholipase activity 2/435 56/18722 0.374978732753787 0.687773223261085 EGFR/PHB 2 GO:0010658 striated muscle cell apoptotic process 2/435 56/18722 0.374978732753787 0.687773223261085 BMP7/BNIP3 2 GO:0015800 acidic amino acid transport 2/435 56/18722 0.374978732753787 0.687773223261085 ARL6IP5/GJA1 2 GO:0030166 proteoglycan biosynthetic process 2/435 56/18722 0.374978732753787 0.687773223261085 EXTL2/CHPF 2 GO:0031529 ruffle organization 2/435 56/18722 0.374978732753787 0.687773223261085 TACSTD2/CAV1 2 GO:0046456 icosanoid biosynthetic process 2/435 56/18722 0.374978732753787 0.687773223261085 MGST3/MIF 2 GO:0055078 sodium ion homeostasis 2/435 56/18722 0.374978732753787 0.687773223261085 COMT/ATP6V1B1 2 GO:0010469 regulation of signaling receptor activity 5/435 173/18722 0.375024341048053 0.687773223261085 PHLDA2/LRPAP1/APP/PARK7/LY6E 5 GO:0000272 polysaccharide catabolic process 1/435 20/18722 0.375259638367623 0.687773223261085 AGL 1 GO:0002834 regulation of response to tumor cell 1/435 20/18722 0.375259638367623 0.687773223261085 HSPD1 1 GO:0002837 regulation of immune response to tumor cell 1/435 20/18722 0.375259638367623 0.687773223261085 HSPD1 1 GO:0006346 DNA methylation-dependent heterochromatin assembly 1/435 20/18722 0.375259638367623 0.687773223261085 DNMT1 1 GO:0006700 C21-steroid hormone biosynthetic process 1/435 20/18722 0.375259638367623 0.687773223261085 AKR1B1 1 GO:0006837 serotonin transport 1/435 20/18722 0.375259638367623 0.687773223261085 SLC6A4 1 GO:0006851 mitochondrial calcium ion transmembrane transport 1/435 20/18722 0.375259638367623 0.687773223261085 STOML2 1 GO:0006896 Golgi to vacuole transport 1/435 20/18722 0.375259638367623 0.687773223261085 CLN3 1 GO:0007620 copulation 1/435 20/18722 0.375259638367623 0.687773223261085 SLC6A4 1 GO:0009713 catechol-containing compound biosynthetic process 1/435 20/18722 0.375259638367623 0.687773223261085 PARK7 1 GO:0010042 response to manganese ion 1/435 20/18722 0.375259638367623 0.687773223261085 APP 1 GO:0014047 glutamate secretion 1/435 20/18722 0.375259638367623 0.687773223261085 GJA1 1 GO:0021516 dorsal spinal cord development 1/435 20/18722 0.375259638367623 0.687773223261085 LMO4 1 GO:0031498 chromatin disassembly 1/435 20/18722 0.375259638367623 0.687773223261085 HMGA1 1 GO:0033005 positive regulation of mast cell activation 1/435 20/18722 0.375259638367623 0.687773223261085 VAMP8 1 GO:0039535 regulation of RIG-I signaling pathway 1/435 20/18722 0.375259638367623 0.687773223261085 C1QBP 1 GO:0042359 vitamin D metabolic process 1/435 20/18722 0.375259638367623 0.687773223261085 LRP2 1 GO:0042423 catecholamine biosynthetic process 1/435 20/18722 0.375259638367623 0.687773223261085 PARK7 1 GO:0043555 regulation of translation in response to stress 1/435 20/18722 0.375259638367623 0.687773223261085 NPM1 1 GO:0043586 tongue development 1/435 20/18722 0.375259638367623 0.687773223261085 EGFR 1 GO:0043651 linoleic acid metabolic process 1/435 20/18722 0.375259638367623 0.687773223261085 GSTP1 1 GO:0046931 pore complex assembly 1/435 20/18722 0.375259638367623 0.687773223261085 BAD 1 GO:0060044 negative regulation of cardiac muscle cell proliferation 1/435 20/18722 0.375259638367623 0.687773223261085 GJA1 1 GO:0060252 positive regulation of glial cell proliferation 1/435 20/18722 0.375259638367623 0.687773223261085 EGFR 1 GO:0061318 renal filtration cell differentiation 1/435 20/18722 0.375259638367623 0.687773223261085 CD24 1 GO:0071397 cellular response to cholesterol 1/435 20/18722 0.375259638367623 0.687773223261085 DAG1 1 GO:0072112 glomerular visceral epithelial cell differentiation 1/435 20/18722 0.375259638367623 0.687773223261085 CD24 1 GO:0090201 negative regulation of release of cytochrome c from mitochondria 1/435 20/18722 0.375259638367623 0.687773223261085 LMNA 1 GO:1901679 nucleotide transmembrane transport 1/435 20/18722 0.375259638367623 0.687773223261085 SLC19A1 1 GO:1902004 positive regulation of amyloid-beta formation 1/435 20/18722 0.375259638367623 0.687773223261085 EFNA1 1 GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 1/435 20/18722 0.375259638367623 0.687773223261085 PARK7 1 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/435 20/18722 0.375259638367623 0.687773223261085 PARK7 1 GO:1903817 negative regulation of voltage-gated potassium channel activity 1/435 20/18722 0.375259638367623 0.687773223261085 CAV1 1 GO:1904263 positive regulation of TORC1 signaling 1/435 20/18722 0.375259638367623 0.687773223261085 LAMTOR5 1 GO:2000010 positive regulation of protein localization to cell surface 1/435 20/18722 0.375259638367623 0.687773223261085 HSP90AB1 1 GO:2000479 regulation of cAMP-dependent protein kinase activity 1/435 20/18722 0.375259638367623 0.687773223261085 PKIB 1 GO:0009165 nucleotide biosynthetic process 7/435 254/18722 0.377566293127232 0.691680473103916 QPRT/PARP1/ACSS1/PNP/TECR/MPC2/STOML2 7 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 4/435 134/18722 0.37853021104992 0.692591941287752 BCAP31/HSP90AB1/PARK7/CAV1 4 GO:0001659 temperature homeostasis 5/435 174/18722 0.379638220932259 0.692591941287752 GNAS/GJA1/ADRB1/ACADVL/CAV1 5 GO:0045619 regulation of lymphocyte differentiation 5/435 174/18722 0.379638220932259 0.692591941287752 SOD1/PRDX2/PNP/BAD/CD46 5 GO:0002532 production of molecular mediator involved in inflammatory response 3/435 95/18722 0.380014143645602 0.692591941287752 VAMP8/RPS19/PRDX2 3 GO:0007044 cell-substrate junction assembly 3/435 95/18722 0.380014143645602 0.692591941287752 ITGA6/ITGB4/S100A10 3 GO:0008585 female gonad development 3/435 95/18722 0.380014143645602 0.692591941287752 SOD1/IDH1/NR2F2 3 GO:0008593 regulation of Notch signaling pathway 3/435 95/18722 0.380014143645602 0.692591941287752 GALNT11/BMP7/CD46 3 GO:0042982 amyloid precursor protein metabolic process 3/435 95/18722 0.380014143645602 0.692591941287752 CLN3/EFNA1/NSG1 3 GO:0048709 oligodendrocyte differentiation 3/435 95/18722 0.380014143645602 0.692591941287752 GSTP1/DAG1/BNIP3 3 GO:1990823 response to leukemia inhibitory factor 3/435 95/18722 0.380014143645602 0.692591941287752 RPS16/NRP2/PCOLCE2 3 GO:0006611 protein export from nucleus 2/435 57/18722 0.383290292159297 0.692591941287752 PARK7/CALR 2 GO:0006754 ATP biosynthetic process 2/435 57/18722 0.383290292159297 0.692591941287752 PARP1/STOML2 2 GO:0010883 regulation of lipid storage 2/435 57/18722 0.383290292159297 0.692591941287752 MEST/HILPDA 2 GO:0030219 megakaryocyte differentiation 2/435 57/18722 0.383290292159297 0.692591941287752 WASF2/PRMT1 2 GO:0097120 receptor localization to synapse 2/435 57/18722 0.383290292159297 0.692591941287752 DAG1/NSG1 2 GO:0090596 sensory organ morphogenesis 7/435 256/18722 0.385165836928123 0.692591941287752 EFEMP1/SOD1/FBN2/BMP7/FBN1/TENM3/ATP6V1B1 7 GO:1901293 nucleoside phosphate biosynthetic process 7/435 256/18722 0.385165836928123 0.692591941287752 QPRT/PARP1/ACSS1/PNP/TECR/MPC2/STOML2 7 GO:0032102 negative regulation of response to external stimulus 11/435 420/18722 0.386036730625104 0.692591941287752 SERPINF1/ANXA2/GSTP1/SOD1/RPS19/PRDX2/GJA1/NENF/C1QBP/MIF/LPCAT3 11 GO:0006637 acyl-CoA metabolic process 3/435 96/18722 0.386322438837684 0.692591941287752 ACSS1/TECR/MPC2 3 GO:0034620 cellular response to unfolded protein 3/435 96/18722 0.386322438837684 0.692591941287752 HSPD1/CCND1/ERLEC1 3 GO:0035383 thioester metabolic process 3/435 96/18722 0.386322438837684 0.692591941287752 ACSS1/TECR/MPC2 3 GO:0044264 cellular polysaccharide metabolic process 3/435 96/18722 0.386322438837684 0.692591941287752 PHLDA2/UGP2/AGL 3 GO:0009612 response to mechanical stimulus 6/435 216/18722 0.387343746762995 0.692591941287752 EGFR/SLC2A1/GJA1/DAG1/BAD/BNIP3 6 GO:0010634 positive regulation of epithelial cell migration 5/435 176/18722 0.388862598185559 0.692591941287752 NRP2/ANXA3/MET/CALR/PDCD6 5 GO:0050728 negative regulation of inflammatory response 5/435 176/18722 0.388862598185559 0.692591941287752 SERPINF1/GSTP1/SOD1/RPS19/LPCAT3 5 GO:0030217 T cell differentiation 7/435 257/18722 0.38896730632887 0.692591941287752 CTSL/SOD1/PRDX2/PNP/BAD/CD46/KDELR1 7 GO:0048511 rhythmic process 8/435 298/18722 0.38969003197112 0.692591941287752 SERPINF1/CLDN4/MAGED1/EGFR/ADRB1/SLC6A4/ASS1/DDB1 8 GO:0000002 mitochondrial genome maintenance 1/435 21/18722 0.389790814568568 0.692591941287752 PARP1 1 GO:0002689 negative regulation of leukocyte chemotaxis 1/435 21/18722 0.389790814568568 0.692591941287752 MIF 1 GO:0003177 pulmonary valve development 1/435 21/18722 0.389790814568568 0.692591941287752 GJA5 1 GO:0006925 inflammatory cell apoptotic process 1/435 21/18722 0.389790814568568 0.692591941287752 CTSL 1 GO:0007252 I-kappaB phosphorylation 1/435 21/18722 0.389790814568568 0.692591941287752 PRDX4 1 GO:0007350 blastoderm segmentation 1/435 21/18722 0.389790814568568 0.692591941287752 NRP2 1 GO:0007617 mating behavior 1/435 21/18722 0.389790814568568 0.692591941287752 APP 1 GO:0008090 retrograde axonal transport 1/435 21/18722 0.389790814568568 0.692591941287752 SOD1 1 GO:0009067 aspartate family amino acid biosynthetic process 1/435 21/18722 0.389790814568568 0.692591941287752 ADI1 1 GO:0019370 leukotriene biosynthetic process 1/435 21/18722 0.389790814568568 0.692591941287752 MGST3 1 GO:0023019 signal transduction involved in regulation of gene expression 1/435 21/18722 0.389790814568568 0.692591941287752 PARP1 1 GO:0032288 myelin assembly 1/435 21/18722 0.389790814568568 0.692591941287752 ITGB4 1 GO:0033630 positive regulation of cell adhesion mediated by integrin 1/435 21/18722 0.389790814568568 0.692591941287752 FERMT1 1 GO:0034035 purine ribonucleoside bisphosphate metabolic process 1/435 21/18722 0.389790814568568 0.692591941287752 TPST2 1 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation 1/435 21/18722 0.389790814568568 0.692591941287752 WASF2 1 GO:0035813 regulation of renal sodium excretion 1/435 21/18722 0.389790814568568 0.692591941287752 COMT 1 GO:0042454 ribonucleoside catabolic process 1/435 21/18722 0.389790814568568 0.692591941287752 PNP 1 GO:0043373 CD4-positive, alpha-beta T cell lineage commitment 1/435 21/18722 0.389790814568568 0.692591941287752 CTSL 1 GO:0044241 lipid digestion 1/435 21/18722 0.389790814568568 0.692591941287752 LPCAT3 1 GO:0044342 type B pancreatic cell proliferation 1/435 21/18722 0.389790814568568 0.692591941287752 BAD 1 GO:0045717 negative regulation of fatty acid biosynthetic process 1/435 21/18722 0.389790814568568 0.692591941287752 ACADVL 1 GO:0046128 purine ribonucleoside metabolic process 1/435 21/18722 0.389790814568568 0.692591941287752 PNP 1 GO:0046599 regulation of centriole replication 1/435 21/18722 0.389790814568568 0.692591941287752 NPM1 1 GO:0046641 positive regulation of alpha-beta T cell proliferation 1/435 21/18722 0.389790814568568 0.692591941287752 CD55 1 GO:0048485 sympathetic nervous system development 1/435 21/18722 0.389790814568568 0.692591941287752 NRP2 1 GO:0048714 positive regulation of oligodendrocyte differentiation 1/435 21/18722 0.389790814568568 0.692591941287752 DAG1 1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process 1/435 21/18722 0.389790814568568 0.692591941287752 TPST2 1 GO:0050802 circadian sleep/wake cycle, sleep 1/435 21/18722 0.389790814568568 0.692591941287752 ADRB1 1 GO:0051767 nitric-oxide synthase biosynthetic process 1/435 21/18722 0.389790814568568 0.692591941287752 GSTP1 1 GO:0051769 regulation of nitric-oxide synthase biosynthetic process 1/435 21/18722 0.389790814568568 0.692591941287752 GSTP1 1 GO:0060117 auditory receptor cell development 1/435 21/18722 0.389790814568568 0.692591941287752 SOD1 1 GO:0071498 cellular response to fluid shear stress 1/435 21/18722 0.389790814568568 0.692591941287752 ASS1 1 GO:0071605 monocyte chemotactic protein-1 production 1/435 21/18722 0.389790814568568 0.692591941287752 GSTP1 1 GO:0071637 regulation of monocyte chemotactic protein-1 production 1/435 21/18722 0.389790814568568 0.692591941287752 GSTP1 1 GO:0072111 cell proliferation involved in kidney development 1/435 21/18722 0.389790814568568 0.692591941287752 BMP7 1 GO:0072311 glomerular epithelial cell differentiation 1/435 21/18722 0.389790814568568 0.692591941287752 CD24 1 GO:0098856 intestinal lipid absorption 1/435 21/18722 0.389790814568568 0.692591941287752 LPCAT3 1 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1/435 21/18722 0.389790814568568 0.692591941287752 MIF 1 GO:1902473 regulation of protein localization to synapse 1/435 21/18722 0.389790814568568 0.692591941287752 DAG1 1 GO:1902644 tertiary alcohol metabolic process 1/435 21/18722 0.389790814568568 0.692591941287752 AKR1B1 1 GO:0035904 aorta development 2/435 58/18722 0.391554013421046 0.69478889287313 LRP2/ADAMTS6 2 GO:0043506 regulation of JUN kinase activity 2/435 58/18722 0.391554013421046 0.69478889287313 GSTP1/RPS3 2 GO:1902808 positive regulation of cell cycle G1/S phase transition 2/435 58/18722 0.391554013421046 0.69478889287313 EGFR/CCND1 2 GO:0014909 smooth muscle cell migration 3/435 97/18722 0.392615529359498 0.696048230141368 GSTP1/S100A11/S1PR2 3 GO:1901216 positive regulation of neuron death 3/435 97/18722 0.392615529359498 0.696048230141368 PARP1/BAD/FIS1 3 GO:0000086 G2/M transition of mitotic cell cycle 4/435 137/18722 0.394332691495478 0.698154120916155 APP/SKP2/CCND1/LCMT1 4 GO:0007266 Rho protein signal transduction 4/435 137/18722 0.394332691495478 0.698154120916155 ADGRG1/MET/HACD3/CTNNAL1 4 GO:0050684 regulation of mRNA processing 4/435 137/18722 0.394332691495478 0.698154120916155 MBNL3/PRDX6/C1QBP/NPM1 4 GO:0050803 regulation of synapse structure or activity 6/435 218/18722 0.395640849598902 0.700156906020955 NRP2/APP/CLN3/EFNA1/DAG1/RAB17 6 GO:0016050 vesicle organization 8/435 300/18722 0.396750399119621 0.701806584406053 ANXA2/VAMP8/CLN3/TMED9/S100A10/SNX3/CAV1/PDCD6 8 GO:0006109 regulation of carbohydrate metabolic process 5/435 178/18722 0.39807833268614 0.703526557587787 PHLDA2/APP/BAD/DDB1/LCMT1 5 GO:0035265 organ growth 5/435 178/18722 0.39807833268614 0.703526557587787 SOD1/DUSP9/GJA1/SLC6A4/LY6E 5 GO:0043502 regulation of muscle adaptation 3/435 98/18722 0.398892067119297 0.703832886423277 PARP1/DAG1/LMNA 3 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 3/435 98/18722 0.398892067119297 0.703832886423277 NDUFA13/PARK7/MIF 3 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 4/435 138/18722 0.399587432762988 0.703832886423277 NPM1/SKP2/CAV1/PDCD6 4 GO:0002820 negative regulation of adaptive immune response 2/435 59/18722 0.399767632598533 0.703832886423277 CD46/CD55 2 GO:0035306 positive regulation of dephosphorylation 2/435 59/18722 0.399767632598533 0.703832886423277 HSP90AB1/SLC39A10 2 GO:0051353 positive regulation of oxidoreductase activity 2/435 59/18722 0.399767632598533 0.703832886423277 NDUFA4/PARK7 2 GO:0006913 nucleocytoplasmic transport 8/435 301/18722 0.400281563855797 0.703832886423277 CDH1/RPL23/HSP90AB1/PARK7/CALR/LMNA/FERMT1/NPM1 8 GO:0051169 nuclear transport 8/435 301/18722 0.400281563855797 0.703832886423277 CDH1/RPL23/HSP90AB1/PARK7/CALR/LMNA/FERMT1/NPM1 8 GO:0051091 positive regulation of DNA-binding transcription factor activity 7/435 260/18722 0.400374196393936 0.703832886423277 ANXA3/APP/RPS3/PARK7/LAMTOR5/NPM1/CAV1 7 GO:0006941 striated muscle contraction 5/435 179/18722 0.402681438623212 0.703832886423277 DSP/GJA1/GJA5/DSC2/CAV1 5 GO:0006359 regulation of transcription by RNA polymerase III 1/435 22/18722 0.4039847611844 0.703832886423277 PRDX5 1 GO:0006379 mRNA cleavage 1/435 22/18722 0.4039847611844 0.703832886423277 POLR2I 1 GO:0006662 glycerol ether metabolic process 1/435 22/18722 0.4039847611844 0.703832886423277 TXN2 1 GO:0007398 ectoderm development 1/435 22/18722 0.4039847611844 0.703832886423277 ITGA6 1 GO:0010310 regulation of hydrogen peroxide metabolic process 1/435 22/18722 0.4039847611844 0.703832886423277 PRDX2 1 GO:0019400 alditol metabolic process 1/435 22/18722 0.4039847611844 0.703832886423277 AKR1B1 1 GO:0031061 negative regulation of histone methylation 1/435 22/18722 0.4039847611844 0.703832886423277 DNMT1 1 GO:0032098 regulation of appetite 1/435 22/18722 0.4039847611844 0.703832886423277 NENF 1 GO:0032402 melanosome transport 1/435 22/18722 0.4039847611844 0.703832886423277 RAB17 1 GO:0032727 positive regulation of interferon-alpha production 1/435 22/18722 0.4039847611844 0.703832886423277 HSPD1 1 GO:0035024 negative regulation of Rho protein signal transduction 1/435 22/18722 0.4039847611844 0.703832886423277 MET 1 GO:0035809 regulation of urine volume 1/435 22/18722 0.4039847611844 0.703832886423277 AKR1B1 1 GO:0042749 regulation of circadian sleep/wake cycle 1/435 22/18722 0.4039847611844 0.703832886423277 ADRB1 1 GO:0043486 histone exchange 1/435 22/18722 0.4039847611844 0.703832886423277 ZNHIT1 1 GO:0048026 positive regulation of mRNA splicing, via spliceosome 1/435 22/18722 0.4039847611844 0.703832886423277 PRDX6 1 GO:0048169 regulation of long-term neuronal synaptic plasticity 1/435 22/18722 0.4039847611844 0.703832886423277 APP 1 GO:0051151 negative regulation of smooth muscle cell differentiation 1/435 22/18722 0.4039847611844 0.703832886423277 DNMT1 1 GO:0060343 trabecula formation 1/435 22/18722 0.4039847611844 0.703832886423277 FBN2 1 GO:0060965 negative regulation of gene silencing by miRNA 1/435 22/18722 0.4039847611844 0.703832886423277 LIN28B 1 GO:0090280 positive regulation of calcium ion import 1/435 22/18722 0.4039847611844 0.703832886423277 LGALS3 1 GO:0097164 ammonium ion metabolic process 1/435 22/18722 0.4039847611844 0.703832886423277 ALDH7A1 1 GO:1900543 negative regulation of purine nucleotide metabolic process 1/435 22/18722 0.4039847611844 0.703832886423277 PARP1 1 GO:0051783 regulation of nuclear division 4/435 139/18722 0.404834369959308 0.703832886423277 BMP7/AURKAIP1/CALR/LCMT1 4 GO:0002444 myeloid leukocyte mediated immunity 3/435 99/18722 0.405150743168333 0.703832886423277 VAMP8/ANXA3/S100A13 3 GO:0010717 regulation of epithelial to mesenchymal transition 3/435 99/18722 0.405150743168333 0.703832886423277 BMP7/EFNA1/DAG1 3 GO:0033209 tumor necrosis factor-mediated signaling pathway 3/435 99/18722 0.405150743168333 0.703832886423277 KRT18/GSTP1/KRT8 3 GO:0042100 B cell proliferation 3/435 99/18722 0.405150743168333 0.703832886423277 HSPD1/SLC39A10/MIF 3 GO:0060291 long-term synaptic potentiation 3/435 99/18722 0.405150743168333 0.703832886423277 MME/APP/NSG1 3 GO:0009259 ribonucleotide metabolic process 10/435 385/18722 0.40518860633617 0.703832886423277 PARP1/ACSS1/APP/PNP/TECR/NUDT4/MPC2/BAD/STOML2/TPST2 10 GO:0031331 positive regulation of cellular catabolic process 11/435 427/18722 0.406827077186904 0.705187906203594 LRP2/APP/BCAP31/PARK7/BAD/TMEM59/LIN28B/SCOC/PSMC1/BNIP3/CAV1 11 GO:0043254 regulation of protein-containing complex assembly 11/435 427/18722 0.406827077186904 0.705187906203594 LMO4/MET/PARP1/RPS3/PARK7/LGALS3/FERMT1/KANK4/RHOC/WASF2/LCMT1 11 GO:0015698 inorganic anion transport 5/435 180/18722 0.407280575564541 0.705187906203594 FXYD3/CLDN4/SLC25A3/CLIC3/SLC22A11 5 GO:0071897 DNA biosynthetic process 5/435 180/18722 0.407280575564541 0.705187906203594 PKIB/GJA1/HSP90AB1/NHP2/PHB 5 GO:0060070 canonical Wnt signaling pathway 8/435 303/18722 0.407344431922106 0.705187906203594 RPS12/EGFR/FOLR1/WLS/LGR5/FERMT1/TBL1X/CAV1 8 GO:0002712 regulation of B cell mediated immunity 2/435 60/18722 0.407929016249691 0.705187906203594 CD46/CD55 2 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 2/435 60/18722 0.407929016249691 0.705187906203594 C1QBP/PHB 2 GO:0002889 regulation of immunoglobulin mediated immune response 2/435 60/18722 0.407929016249691 0.705187906203594 CD46/CD55 2 GO:0006893 Golgi to plasma membrane transport 2/435 60/18722 0.407929016249691 0.705187906203594 KRT18/CLN3 2 GO:0031663 lipopolysaccharide-mediated signaling pathway 2/435 60/18722 0.407929016249691 0.705187906203594 PRDX2/CD55 2 GO:0051851 modulation by host of symbiont process 2/435 60/18722 0.407929016249691 0.705187906203594 PPIB/PHB 2 GO:0031333 negative regulation of protein-containing complex assembly 4/435 140/18722 0.410072670522709 0.707198301043944 LMO4/PARK7/KANK4/LCMT1 4 GO:0019218 regulation of steroid metabolic process 3/435 100/18722 0.411390287344 0.707198301043944 SOD1/ACADVL/LPCAT3 3 GO:0046545 development of primary female sexual characteristics 3/435 100/18722 0.411390287344 0.707198301043944 SOD1/IDH1/NR2F2 3 GO:0008361 regulation of cell size 5/435 181/18722 0.411875157610045 0.707198301043944 CLN3/HSP90AB1/LAMTOR5/KCNN4/NPM1 5 GO:0032640 tumor necrosis factor production 5/435 181/18722 0.411875157610045 0.707198301043944 GSTP1/HSPD1/APP/MIF/CD47 5 GO:0032680 regulation of tumor necrosis factor production 5/435 181/18722 0.411875157610045 0.707198301043944 GSTP1/HSPD1/APP/MIF/CD47 5 GO:0016241 regulation of macroautophagy 4/435 141/18722 0.415301518113888 0.707198301043944 CLN3/ATP6V1B1/SCOC/BNIP3 4 GO:0016571 histone methylation 4/435 141/18722 0.415301518113888 0.707198301043944 DNMT1/LMNA/TRMT112/PRMT1 4 GO:0030199 collagen fibril organization 2/435 61/18722 0.416036156613429 0.707198301043944 ANXA2/COL14A1 2 GO:0030865 cortical cytoskeleton organization 2/435 61/18722 0.416036156613429 0.707198301043944 CALR/RHOC 2 GO:0043030 regulation of macrophage activation 2/435 61/18722 0.416036156613429 0.707198301043944 HSPD1/MIF 2 GO:1904356 regulation of telomere maintenance via telomere lengthening 2/435 61/18722 0.416036156613429 0.707198301043944 PKIB/PARP1 2 GO:0006936 muscle contraction 9/435 347/18722 0.416312506080911 0.707198301043944 SOD1/DSP/GJA1/GJA5/DSC2/ASPH/SSPN/ATP2B1/CAV1 9 GO:0002274 myeloid leukocyte activation 6/435 223/18722 0.416357366666843 0.707198301043944 VAMP8/ANXA3/HSPD1/APP/S100A13/MIF 6 GO:0009260 ribonucleotide biosynthetic process 5/435 182/18722 0.416464607118992 0.707198301043944 PARP1/ACSS1/TECR/MPC2/STOML2 5 GO:0006476 protein deacetylation 3/435 101/18722 0.417609467891661 0.707198301043944 BEX4/PHB/TBL1X 3 GO:0150115 cell-substrate junction organization 3/435 101/18722 0.417609467891661 0.707198301043944 ITGA6/ITGB4/S100A10 3 GO:0002082 regulation of oxidative phosphorylation 1/435 23/18722 0.417849286793212 0.707198301043944 COX7A2 1 GO:0002363 alpha-beta T cell lineage commitment 1/435 23/18722 0.417849286793212 0.707198301043944 CTSL 1 GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 1/435 23/18722 0.417849286793212 0.707198301043944 MME 1 GO:0003283 atrial septum development 1/435 23/18722 0.417849286793212 0.707198301043944 GJA5 1 GO:0003323 type B pancreatic cell development 1/435 23/18722 0.417849286793212 0.707198301043944 BAD 1 GO:0009162 deoxyribonucleoside monophosphate metabolic process 1/435 23/18722 0.417849286793212 0.707198301043944 PNP 1 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 1/435 23/18722 0.417849286793212 0.707198301043944 GSTP1 1 GO:0021871 forebrain regionalization 1/435 23/18722 0.417849286793212 0.707198301043944 ADGRG1 1 GO:0030194 positive regulation of blood coagulation 1/435 23/18722 0.417849286793212 0.707198301043944 PRDX2 1 GO:0030325 adrenal gland development 1/435 23/18722 0.417849286793212 0.707198301043944 LY6E 1 GO:0031338 regulation of vesicle fusion 1/435 23/18722 0.417849286793212 0.707198301043944 ANXA2 1 GO:0032401 establishment of melanosome localization 1/435 23/18722 0.417849286793212 0.707198301043944 RAB17 1 GO:0032740 positive regulation of interleukin-17 production 1/435 23/18722 0.417849286793212 0.707198301043944 PHB 1 GO:0033081 regulation of T cell differentiation in thymus 1/435 23/18722 0.417849286793212 0.707198301043944 SOD1 1 GO:0040019 positive regulation of embryonic development 1/435 23/18722 0.417849286793212 0.707198301043944 AMOT 1 GO:0042026 protein refolding 1/435 23/18722 0.417849286793212 0.707198301043944 HSPD1 1 GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment 1/435 23/18722 0.417849286793212 0.707198301043944 CTSL 1 GO:0045662 negative regulation of myoblast differentiation 1/435 23/18722 0.417849286793212 0.707198301043944 MBNL3 1 GO:0045932 negative regulation of muscle contraction 1/435 23/18722 0.417849286793212 0.707198301043944 SOD1 1 GO:0045980 negative regulation of nucleotide metabolic process 1/435 23/18722 0.417849286793212 0.707198301043944 PARP1 1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process 1/435 23/18722 0.417849286793212 0.707198301043944 CHPF 1 GO:0051349 positive regulation of lyase activity 1/435 23/18722 0.417849286793212 0.707198301043944 PARK7 1 GO:0051457 maintenance of protein location in nucleus 1/435 23/18722 0.417849286793212 0.707198301043944 PARK7 1 GO:0051904 pigment granule transport 1/435 23/18722 0.417849286793212 0.707198301043944 RAB17 1 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization 1/435 23/18722 0.417849286793212 0.707198301043944 GJA5 1 GO:0060547 negative regulation of necrotic cell death 1/435 23/18722 0.417849286793212 0.707198301043944 CAV1 1 GO:0071305 cellular response to vitamin D 1/435 23/18722 0.417849286793212 0.707198301043944 ATP2B1 1 GO:0072677 eosinophil migration 1/435 23/18722 0.417849286793212 0.707198301043944 LGALS3 1 GO:0090335 regulation of brown fat cell differentiation 1/435 23/18722 0.417849286793212 0.707198301043944 BMP7 1 GO:1900048 positive regulation of hemostasis 1/435 23/18722 0.417849286793212 0.707198301043944 PRDX2 1 GO:2000810 regulation of bicellular tight junction assembly 1/435 23/18722 0.417849286793212 0.707198301043944 GJA1 1 GO:2001169 regulation of ATP biosynthetic process 1/435 23/18722 0.417849286793212 0.707198301043944 PARP1 1 GO:0030522 intracellular receptor signaling pathway 7/435 265/18722 0.419372856558876 0.708867318839586 PARP1/NR2F2/PARK7/C1QBP/CALR/PHB/SKP2 7 GO:0051607 defense response to virus 7/435 265/18722 0.419372856558876 0.708867318839586 IFI6/VAMP8/IL10RB/C1QBP/PHB/SKP2/BNIP3 7 GO:0140546 defense response to symbiont 7/435 265/18722 0.419372856558876 0.708867318839586 IFI6/VAMP8/IL10RB/C1QBP/PHB/SKP2/BNIP3 7 GO:0032984 protein-containing complex disassembly 6/435 224/18722 0.420492641506177 0.709436371817789 VAMP8/RPL23/CLN3/HMGA1/DSTN/BNIP3 6 GO:0046467 membrane lipid biosynthetic process 4/435 142/18722 0.420520112654892 0.709436371817789 DEGS1/HACD3/PYURF/ORMDL1 4 GO:0035710 CD4-positive, alpha-beta T cell activation 3/435 102/18722 0.423807091066713 0.709436371817789 CTSL/CD55/STOML2 3 GO:0045833 negative regulation of lipid metabolic process 3/435 102/18722 0.423807091066713 0.709436371817789 SOD1/ACADVL/ORMDL1 3 GO:0062014 negative regulation of small molecule metabolic process 3/435 102/18722 0.423807091066713 0.709436371817789 SOD1/PARP1/ACADVL 3 GO:1902749 regulation of cell cycle G2/M phase transition 3/435 102/18722 0.423807091066713 0.709436371817789 APP/NPM1/CCND1 3 GO:0032757 positive regulation of interleukin-8 production 2/435 62/18722 0.424087166944747 0.709436371817789 PARK7/LAMTOR5 2 GO:0032835 glomerulus development 2/435 62/18722 0.424087166944747 0.709436371817789 CD24/BMP7 2 GO:0045576 mast cell activation 2/435 62/18722 0.424087166944747 0.709436371817789 VAMP8/S100A13 2 GO:0046173 polyol biosynthetic process 2/435 62/18722 0.424087166944747 0.709436371817789 ISYNA1/AKR1B1 2 GO:0046824 positive regulation of nucleocytoplasmic transport 2/435 62/18722 0.424087166944747 0.709436371817789 CDH1/HSP90AB1 2 GO:0048002 antigen processing and presentation of peptide antigen 2/435 62/18722 0.424087166944747 0.709436371817789 CTSL/CALR 2 GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 2/435 62/18722 0.424087166944747 0.709436371817789 DAG1/NSG1 2 GO:0030010 establishment of cell polarity 4/435 143/18722 0.425727670356028 0.709436371817789 GJA1/HSP90AB1/FERMT1/AMOT 4 GO:0062013 positive regulation of small molecule metabolic process 4/435 143/18722 0.425727670356028 0.709436371817789 COMT/APP/PARK7/DDB1 4 GO:0002683 negative regulation of immune system process 11/435 434/18722 0.427653880527598 0.709436371817789 RPS19/PRDX2/CD59/FBN1/C1QBP/LGALS3/CD46/MIF/CD55/PHPT1/CD47 11 GO:0030148 sphingolipid biosynthetic process 3/435 103/18722 0.429982000718378 0.709436371817789 DEGS1/HACD3/ORMDL1 3 GO:0032760 positive regulation of tumor necrosis factor production 3/435 103/18722 0.429982000718378 0.709436371817789 HSPD1/APP/MIF 3 GO:0046425 regulation of receptor signaling pathway via JAK-STAT 3/435 103/18722 0.429982000718378 0.709436371817789 IL10RB/AKR1B1/CAV1 3 GO:0001894 tissue homeostasis 7/435 268/18722 0.430749267566574 0.709436371817789 SOD1/EGFR/PRDX1/SLC2A1/GJA1/AKR1B1/LSR 7 GO:0031644 regulation of nervous system process 4/435 144/18722 0.430923423731156 0.709436371817789 COMT/APP/DAG1/S1PR2 4 GO:0106106 cold-induced thermogenesis 4/435 144/18722 0.430923423731156 0.709436371817789 GNAS/GJA1/ADRB1/CAV1 4 GO:0120161 regulation of cold-induced thermogenesis 4/435 144/18722 0.430923423731156 0.709436371817789 GNAS/GJA1/ADRB1/CAV1 4 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/435 24/18722 0.43139201957277 0.709436371817789 RPS21 1 GO:0001702 gastrulation with mouth forming second 1/435 24/18722 0.43139201957277 0.709436371817789 AMOT 1 GO:0001783 B cell apoptotic process 1/435 24/18722 0.43139201957277 0.709436371817789 SLC39A10 1 GO:0002021 response to dietary excess 1/435 24/18722 0.43139201957277 0.709436371817789 ADRB1 1 GO:0002438 acute inflammatory response to antigenic stimulus 1/435 24/18722 0.43139201957277 0.709436371817789 PARK7 1 GO:0002726 positive regulation of T cell cytokine production 1/435 24/18722 0.43139201957277 0.709436371817789 CD55 1 GO:0002755 MyD88-dependent toll-like receptor signaling pathway 1/435 24/18722 0.43139201957277 0.709436371817789 HSPD1 1 GO:0002922 positive regulation of humoral immune response 1/435 24/18722 0.43139201957277 0.709436371817789 PHB 1 GO:0003181 atrioventricular valve morphogenesis 1/435 24/18722 0.43139201957277 0.709436371817789 EFNA1 1 GO:0006817 phosphate ion transport 1/435 24/18722 0.43139201957277 0.709436371817789 SLC25A3 1 GO:0007035 vacuolar acidification 1/435 24/18722 0.43139201957277 0.709436371817789 CLN3 1 GO:0010288 response to lead ion 1/435 24/18722 0.43139201957277 0.709436371817789 APP 1 GO:0021801 cerebral cortex radial glia-guided migration 1/435 24/18722 0.43139201957277 0.709436371817789 ADGRG1 1 GO:0022030 telencephalon glial cell migration 1/435 24/18722 0.43139201957277 0.709436371817789 ADGRG1 1 GO:0022410 circadian sleep/wake cycle process 1/435 24/18722 0.43139201957277 0.709436371817789 ADRB1 1 GO:0035458 cellular response to interferon-beta 1/435 24/18722 0.43139201957277 0.709436371817789 NDUFA13 1 GO:0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 1/435 24/18722 0.43139201957277 0.709436371817789 C1QBP 1 GO:0043302 positive regulation of leukocyte degranulation 1/435 24/18722 0.43139201957277 0.709436371817789 VAMP8 1 GO:0044062 regulation of excretion 1/435 24/18722 0.43139201957277 0.709436371817789 COMT 1 GO:0050687 negative regulation of defense response to virus 1/435 24/18722 0.43139201957277 0.709436371817789 C1QBP 1 GO:0050820 positive regulation of coagulation 1/435 24/18722 0.43139201957277 0.709436371817789 PRDX2 1 GO:0050855 regulation of B cell receptor signaling pathway 1/435 24/18722 0.43139201957277 0.709436371817789 SLC39A10 1 GO:0051123 RNA polymerase II preinitiation complex assembly 1/435 24/18722 0.43139201957277 0.709436371817789 GTF2A2 1 GO:0051156 glucose 6-phosphate metabolic process 1/435 24/18722 0.43139201957277 0.709436371817789 RPIA 1 GO:0051905 establishment of pigment granule localization 1/435 24/18722 0.43139201957277 0.709436371817789 RAB17 1 GO:0051923 sulfation 1/435 24/18722 0.43139201957277 0.709436371817789 TPST2 1 GO:0060149 negative regulation of posttranscriptional gene silencing 1/435 24/18722 0.43139201957277 0.709436371817789 LIN28B 1 GO:0060561 apoptotic process involved in morphogenesis 1/435 24/18722 0.43139201957277 0.709436371817789 BMP7 1 GO:0060571 morphogenesis of an epithelial fold 1/435 24/18722 0.43139201957277 0.709436371817789 BMP7 1 GO:0060967 negative regulation of gene silencing by RNA 1/435 24/18722 0.43139201957277 0.709436371817789 LIN28B 1 GO:0070129 regulation of mitochondrial translation 1/435 24/18722 0.43139201957277 0.709436371817789 C1QBP 1 GO:0071294 cellular response to zinc ion 1/435 24/18722 0.43139201957277 0.709436371817789 PARP1 1 GO:0072010 glomerular epithelium development 1/435 24/18722 0.43139201957277 0.709436371817789 CD24 1 GO:0072530 purine-containing compound transmembrane transport 1/435 24/18722 0.43139201957277 0.709436371817789 SLC19A1 1 GO:0090023 positive regulation of neutrophil chemotaxis 1/435 24/18722 0.43139201957277 0.709436371817789 C1QBP 1 GO:0120255 olefinic compound biosynthetic process 1/435 24/18722 0.43139201957277 0.709436371817789 HSD17B1 1 GO:1901984 negative regulation of protein acetylation 1/435 24/18722 0.43139201957277 0.709436371817789 PARK7 1 GO:1903077 negative regulation of protein localization to plasma membrane 1/435 24/18722 0.43139201957277 0.709436371817789 TMEM59 1 GO:1903428 positive regulation of reactive oxygen species biosynthetic process 1/435 24/18722 0.43139201957277 0.709436371817789 PARK7 1 GO:2000209 regulation of anoikis 1/435 24/18722 0.43139201957277 0.709436371817789 CAV1 1 GO:2000310 regulation of NMDA receptor activity 1/435 24/18722 0.43139201957277 0.709436371817789 APP 1 GO:2001026 regulation of endothelial cell chemotaxis 1/435 24/18722 0.43139201957277 0.709436371817789 MET 1 GO:0002704 negative regulation of leukocyte mediated immunity 2/435 63/18722 0.432080276997946 0.709436371817789 CD46/CD55 2 GO:0016239 positive regulation of macroautophagy 2/435 63/18722 0.432080276997946 0.709436371817789 SCOC/BNIP3 2 GO:0030239 myofibril assembly 2/435 63/18722 0.432080276997946 0.709436371817789 KRT8/CSRP2 2 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 2/435 63/18722 0.432080276997946 0.709436371817789 ERP29/PARK7 2 GO:0071706 tumor necrosis factor superfamily cytokine production 5/435 186/18722 0.434759820468133 0.712948449893247 GSTP1/HSPD1/APP/MIF/CD47 5 GO:0120032 regulation of plasma membrane bounded cell projection assembly 5/435 186/18722 0.434759820468133 0.712948449893247 CLN3/TACSTD2/CAV1/WASF2/RAB17 5 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 5/435 186/18722 0.434759820468133 0.712948449893247 GSTP1/HSPD1/APP/MIF/CD47 5 GO:0006892 post-Golgi vesicle-mediated transport 3/435 104/18722 0.436133077856651 0.714072456141943 KRT18/CLN3/SCAMP2 3 GO:0032006 regulation of TOR signaling 3/435 104/18722 0.436133077856651 0.714072456141943 LAMTOR5/SLC38A9/PDCD6 3 GO:0045621 positive regulation of lymphocyte differentiation 3/435 104/18722 0.436133077856651 0.714072456141943 PNP/BAD/CD46 3 GO:0051480 regulation of cytosolic calcium ion concentration 9/435 353/18722 0.436167077709142 0.714072456141943 CD24/TGM2/GJA1/CLN3/BCAP31/CD55/FIS1/ATP2B1/CAV1 9 GO:0033044 regulation of chromosome organization 5/435 187/18722 0.439315237152768 0.718289900982807 PKIB/DNMT1/PARP1/SSBP1/LCMT1 5 GO:0061136 regulation of proteasomal protein catabolic process 5/435 187/18722 0.439315237152768 0.718289900982807 BCAP31/HSP90AB1/PARK7/PSMC1/CAV1 5 GO:0006163 purine nucleotide metabolic process 10/435 396/18722 0.439602917002496 0.718289900982807 PARP1/ACSS1/APP/PNP/TECR/NUDT4/MPC2/BAD/STOML2/TPST2 10 GO:0001885 endothelial cell development 2/435 64/18722 0.440013828653607 0.718289900982807 MET/S1PR2 2 GO:0030858 positive regulation of epithelial cell differentiation 2/435 64/18722 0.440013828653607 0.718289900982807 CD24/BAD 2 GO:0030888 regulation of B cell proliferation 2/435 64/18722 0.440013828653607 0.718289900982807 SLC39A10/MIF 2 GO:0055002 striated muscle cell development 2/435 64/18722 0.440013828653607 0.718289900982807 KRT8/CSRP2 2 GO:0010675 regulation of cellular carbohydrate metabolic process 4/435 146/18722 0.441276529090517 0.718400558653594 PHLDA2/BAD/DDB1/LCMT1 4 GO:2001022 positive regulation of response to DNA damage stimulus 3/435 105/18722 0.442259240203763 0.718400558653594 EGFR/PARP1/RPS3 3 GO:0060491 regulation of cell projection assembly 5/435 188/18722 0.443862233064234 0.718400558653594 CLN3/TACSTD2/CAV1/WASF2/RAB17 5 GO:0010447 response to acidic pH 1/435 25/18722 0.444620411458846 0.718400558653594 SERPINF1 1 GO:0010954 positive regulation of protein processing 1/435 25/18722 0.444620411458846 0.718400558653594 LPCAT3 1 GO:0015012 heparan sulfate proteoglycan biosynthetic process 1/435 25/18722 0.444620411458846 0.718400558653594 EXTL2 1 GO:0032104 regulation of response to extracellular stimulus 1/435 25/18722 0.444620411458846 0.718400558653594 NENF 1 GO:0032107 regulation of response to nutrient levels 1/435 25/18722 0.444620411458846 0.718400558653594 NENF 1 GO:0032331 negative regulation of chondrocyte differentiation 1/435 25/18722 0.444620411458846 0.718400558653594 EFEMP1 1 GO:0032400 melanosome localization 1/435 25/18722 0.444620411458846 0.718400558653594 RAB17 1 GO:0033233 regulation of protein sumoylation 1/435 25/18722 0.444620411458846 0.718400558653594 PARK7 1 GO:0033622 integrin activation 1/435 25/18722 0.444620411458846 0.718400558653594 FERMT1 1 GO:0035336 long-chain fatty-acyl-CoA metabolic process 1/435 25/18722 0.444620411458846 0.718400558653594 TECR 1 GO:0036315 cellular response to sterol 1/435 25/18722 0.444620411458846 0.718400558653594 DAG1 1 GO:0042730 fibrinolysis 1/435 25/18722 0.444620411458846 0.718400558653594 ANXA2 1 GO:0045109 intermediate filament organization 1/435 25/18722 0.444620411458846 0.718400558653594 DSP 1 GO:0046949 fatty-acyl-CoA biosynthetic process 1/435 25/18722 0.444620411458846 0.718400558653594 TECR 1 GO:0048596 embryonic camera-type eye morphogenesis 1/435 25/18722 0.444620411458846 0.718400558653594 BMP7 1 GO:0060740 prostate gland epithelium morphogenesis 1/435 25/18722 0.444620411458846 0.718400558653594 BMP7 1 GO:0072012 glomerulus vasculature development 1/435 25/18722 0.444620411458846 0.718400558653594 BMP7 1 GO:0090382 phagosome maturation 1/435 25/18722 0.444620411458846 0.718400558653594 CLN3 1 GO:1902993 positive regulation of amyloid precursor protein catabolic process 1/435 25/18722 0.444620411458846 0.718400558653594 EFNA1 1 GO:1903055 positive regulation of extracellular matrix organization 1/435 25/18722 0.444620411458846 0.718400558653594 DAG1 1 GO:1904385 cellular response to angiotensin 1/435 25/18722 0.444620411458846 0.718400558653594 CAV1 1 GO:1905048 regulation of metallopeptidase activity 1/435 25/18722 0.444620411458846 0.718400558653594 CLDN4 1 GO:0006869 lipid transport 10/435 398/18722 0.445848196480914 0.719836046703239 ANXA2/SLC2A1/SLC27A2/CLN3/STARD10/DBI/FIS1/KCNN4/CAV1/LPCAT3 10 GO:0051962 positive regulation of nervous system development 7/435 272/18722 0.445872668807086 0.719836046703239 SERPINF1/SPINT1/EGFR/LRP2/TGM2/MME/DAG1 7 GO:0060249 anatomical structure homeostasis 8/435 314/18722 0.446110589234548 0.719926428059178 SOD1/EGFR/PRDX1/SLC2A1/GJA1/AKR1B1/ATP2B1/LSR 8 GO:0003170 heart valve development 2/435 65/18722 0.447886271685119 0.720909512771791 GJA5/EFNA1 2 GO:0015909 long-chain fatty acid transport 2/435 65/18722 0.447886271685119 0.720909512771791 SLC2A1/SLC27A2 2 GO:0033692 cellular polysaccharide biosynthetic process 2/435 65/18722 0.447886271685119 0.720909512771791 UGP2/AGL 2 GO:0035418 protein localization to synapse 2/435 65/18722 0.447886271685119 0.720909512771791 DAG1/NSG1 2 GO:0046513 ceramide biosynthetic process 2/435 65/18722 0.447886271685119 0.720909512771791 DEGS1/ORMDL1 2 GO:0006906 vesicle fusion 3/435 106/18722 0.448359441731458 0.720909512771791 ANXA2/VAMP8/CLN3 3 GO:0035821 modulation of process of other organism 3/435 106/18722 0.448359441731458 0.720909512771791 PPIB/DAG1/PHB 3 GO:0042116 macrophage activation 3/435 106/18722 0.448359441731458 0.720909512771791 HSPD1/APP/MIF 3 GO:2000278 regulation of DNA biosynthetic process 3/435 106/18722 0.448359441731458 0.720909512771791 PKIB/GJA1/HSP90AB1 3 GO:0032956 regulation of actin cytoskeleton organization 9/435 357/18722 0.449370724426294 0.721024561496109 MET/S100A10/DSTN/TACSTD2/PHPT1/KANK4/RHOC/WASF2/CD47 9 GO:0002768 immune response-regulating cell surface receptor signaling pathway 8/435 315/18722 0.449620563055097 0.721024561496109 CD24/RPS3/SLC39A10/LGALS3/STOML2/KCNN4/PHPT1/CD47 8 GO:0097530 granulocyte migration 4/435 148/18722 0.45157361480499 0.721024561496109 BSG/PPIB/C1QBP/LGALS3 4 GO:0046390 ribose phosphate biosynthetic process 5/435 190/18722 0.452928899836809 0.721024561496109 PARP1/ACSS1/TECR/MPC2/STOML2 5 GO:0005976 polysaccharide metabolic process 3/435 107/18722 0.454432672185327 0.721024561496109 PHLDA2/UGP2/AGL 3 GO:0021761 limbic system development 3/435 107/18722 0.454432672185327 0.721024561496109 NRP2/UQCRQ/ANXA3 3 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 3/435 107/18722 0.454432672185327 0.721024561496109 HSPD1/APP/MIF 3 GO:0042446 hormone biosynthetic process 2/435 66/18722 0.455696159660651 0.721024561496109 HSD17B1/AKR1B1 2 GO:0045600 positive regulation of fat cell differentiation 2/435 66/18722 0.455696159660651 0.721024561496109 ADIRF/BMP7 2 GO:0050922 negative regulation of chemotaxis 2/435 66/18722 0.455696159660651 0.721024561496109 GSTP1/MIF 2 GO:2000272 negative regulation of signaling receptor activity 2/435 66/18722 0.455696159660651 0.721024561496109 LRPAP1/LY6E 2 GO:2000573 positive regulation of DNA biosynthetic process 2/435 66/18722 0.455696159660651 0.721024561496109 PKIB/HSP90AB1 2 GO:0043270 positive regulation of ion transport 7/435 275/18722 0.457170183347149 0.721024561496109 VAMP8/NDUFA4/SLC6A4/LGALS3/KCNN4/ATP2B1/CAV1 7 GO:0006164 purine nucleotide biosynthetic process 5/435 191/18722 0.457447561238507 0.721024561496109 PARP1/ACSS1/TECR/MPC2/STOML2 5 GO:0007160 cell-matrix adhesion 6/435 233/18722 0.457495035766815 0.721024561496109 BCAM/ITGB4/S100A10/DAG1/FERMT1/ITGB5 6 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 6/435 233/18722 0.457495035766815 0.721024561496109 ADGRG1/GNAS/ADRB1/LGR5/WASF2/S1PR2 6 GO:0002418 immune response to tumor cell 1/435 26/18722 0.457541742207918 0.721024561496109 HSPD1 1 GO:0006027 glycosaminoglycan catabolic process 1/435 26/18722 0.457541742207918 0.721024561496109 FUCA1 1 GO:0006517 protein deglycosylation 1/435 26/18722 0.457541742207918 0.721024561496109 PARK7 1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane 1/435 26/18722 0.457541742207918 0.721024561496109 SRP14 1 GO:0009164 nucleoside catabolic process 1/435 26/18722 0.457541742207918 0.721024561496109 PNP 1 GO:0009435 NAD biosynthetic process 1/435 26/18722 0.457541742207918 0.721024561496109 QPRT 1 GO:0010875 positive regulation of cholesterol efflux 1/435 26/18722 0.457541742207918 0.721024561496109 CAV1 1 GO:0014829 vascular associated smooth muscle contraction 1/435 26/18722 0.457541742207918 0.721024561496109 ATP2B1 1 GO:0015985 energy coupled proton transport, down electrochemical gradient 1/435 26/18722 0.457541742207918 0.721024561496109 STOML2 1 GO:0015986 ATP synthesis coupled proton transport 1/435 26/18722 0.457541742207918 0.721024561496109 STOML2 1 GO:0021680 cerebellar Purkinje cell layer development 1/435 26/18722 0.457541742207918 0.721024561496109 UQCRQ 1 GO:0031167 rRNA methylation 1/435 26/18722 0.457541742207918 0.721024561496109 TRMT112 1 GO:0032515 negative regulation of phosphoprotein phosphatase activity 1/435 26/18722 0.457541742207918 0.721024561496109 LGALS3 1 GO:0032682 negative regulation of chemokine production 1/435 26/18722 0.457541742207918 0.721024561496109 GSTP1 1 GO:0033522 histone H2A ubiquitination 1/435 26/18722 0.457541742207918 0.721024561496109 DDB1 1 GO:0033598 mammary gland epithelial cell proliferation 1/435 26/18722 0.457541742207918 0.721024561496109 CCND1 1 GO:0034063 stress granule assembly 1/435 26/18722 0.457541742207918 0.721024561496109 RPS23 1 GO:0034114 regulation of heterotypic cell-cell adhesion 1/435 26/18722 0.457541742207918 0.721024561496109 BMP7 1 GO:0042278 purine nucleoside metabolic process 1/435 26/18722 0.457541742207918 0.721024561496109 PNP 1 GO:0042634 regulation of hair cycle 1/435 26/18722 0.457541742207918 0.721024561496109 FERMT1 1 GO:0045745 positive regulation of G protein-coupled receptor signaling pathway 1/435 26/18722 0.457541742207918 0.721024561496109 PHB 1 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity 1/435 26/18722 0.457541742207918 0.721024561496109 CADM1 1 GO:0048668 collateral sprouting 1/435 26/18722 0.457541742207918 0.721024561496109 APP 1 GO:0051350 negative regulation of lyase activity 1/435 26/18722 0.457541742207918 0.721024561496109 PHPT1 1 GO:0051875 pigment granule localization 1/435 26/18722 0.457541742207918 0.721024561496109 RAB17 1 GO:0060544 regulation of necroptotic process 1/435 26/18722 0.457541742207918 0.721024561496109 CAV1 1 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway 1/435 26/18722 0.457541742207918 0.721024561496109 ADRB1 1 GO:0097186 amelogenesis 1/435 26/18722 0.457541742207918 0.721024561496109 PERP 1 GO:0099637 neurotransmitter receptor transport 1/435 26/18722 0.457541742207918 0.721024561496109 NSG1 1 GO:1901071 glucosamine-containing compound metabolic process 1/435 26/18722 0.457541742207918 0.721024561496109 EXTL2 1 GO:1902186 regulation of viral release from host cell 1/435 26/18722 0.457541742207918 0.721024561496109 DDB1 1 GO:1904353 regulation of telomere capping 1/435 26/18722 0.457541742207918 0.721024561496109 PKIB 1 GO:1904376 negative regulation of protein localization to cell periphery 1/435 26/18722 0.457541742207918 0.721024561496109 TMEM59 1 GO:1905063 regulation of vascular associated smooth muscle cell differentiation 1/435 26/18722 0.457541742207918 0.721024561496109 DNMT1 1 GO:0002832 negative regulation of response to biotic stimulus 3/435 108/18722 0.460477956597369 0.724785709727841 RPS19/PRDX2/C1QBP 3 GO:0006958 complement activation, classical pathway 3/435 108/18722 0.460477956597369 0.724785709727841 C1QBP/CD46/CD55 3 GO:0007173 epidermal growth factor receptor signaling pathway 3/435 108/18722 0.460477956597369 0.724785709727841 EFEMP1/IFI6/EGFR 3 GO:0001959 regulation of cytokine-mediated signaling pathway 4/435 150/18722 0.461809126980464 0.726591934577215 CD24/GSTP1/HSP90AB1/CAV1 4 GO:0006513 protein monoubiquitination 2/435 67/18722 0.463442145976586 0.72771451255133 DDB1/PDCD6 2 GO:0009880 embryonic pattern specification 2/435 67/18722 0.463442145976586 0.72771451255133 NRP2/BMP7 2 GO:0010517 regulation of phospholipase activity 2/435 67/18722 0.463442145976586 0.72771451255133 EGFR/PHB 2 GO:0046635 positive regulation of alpha-beta T cell activation 2/435 67/18722 0.463442145976586 0.72771451255133 PNP/CD55 2 GO:0050435 amyloid-beta metabolic process 2/435 67/18722 0.463442145976586 0.72771451255133 MME/EFNA1 2 GO:0002456 T cell mediated immunity 3/435 109/18722 0.466494354787925 0.728216262473978 HSPD1/CD46/CD55 3 GO:0006821 chloride transport 3/435 109/18722 0.466494354787925 0.728216262473978 FXYD3/CLDN4/CLIC3 3 GO:0034766 negative regulation of ion transmembrane transport 3/435 109/18722 0.466494354787925 0.728216262473978 ARL6IP5/SLC43A2/CAV1 3 GO:0030902 hindbrain development 4/435 151/18722 0.466902128190637 0.728216262473978 BMP7/UQCRQ/WLS/SLC6A4 4 GO:0002237 response to molecule of bacterial origin 9/435 363/18722 0.469092365011706 0.728216262473978 CD24/GSTP1/COMT/PRDX2/HSPD1/GJA1/ADH5/ASS1/CD55 9 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 1/435 27/18722 0.470163123366431 0.728216262473978 CD47 1 GO:0003272 endocardial cushion formation 1/435 27/18722 0.470163123366431 0.728216262473978 BMP7 1 GO:0006783 heme biosynthetic process 1/435 27/18722 0.470163123366431 0.728216262473978 TMEM14C 1 GO:0007263 nitric oxide mediated signal transduction 1/435 27/18722 0.470163123366431 0.728216262473978 EGFR 1 GO:0010561 negative regulation of glycoprotein biosynthetic process 1/435 27/18722 0.470163123366431 0.728216262473978 TMEM59 1 GO:0010586 miRNA metabolic process 1/435 27/18722 0.470163123366431 0.728216262473978 LIN28B 1 GO:0010758 regulation of macrophage chemotaxis 1/435 27/18722 0.470163123366431 0.728216262473978 MIF 1 GO:0010894 negative regulation of steroid biosynthetic process 1/435 27/18722 0.470163123366431 0.728216262473978 SOD1 1 GO:0014850 response to muscle activity 1/435 27/18722 0.470163123366431 0.728216262473978 FIS1 1 GO:0015813 L-glutamate transmembrane transport 1/435 27/18722 0.470163123366431 0.728216262473978 ARL6IP5 1 GO:0018904 ether metabolic process 1/435 27/18722 0.470163123366431 0.728216262473978 TXN2 1 GO:0033688 regulation of osteoblast proliferation 1/435 27/18722 0.470163123366431 0.728216262473978 ATRAID 1 GO:0034377 plasma lipoprotein particle assembly 1/435 27/18722 0.470163123366431 0.728216262473978 LPCAT3 1 GO:0034453 microtubule anchoring 1/435 27/18722 0.470163123366431 0.728216262473978 DAG1 1 GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 1/435 27/18722 0.470163123366431 0.728216262473978 CD47 1 GO:0042745 circadian sleep/wake cycle 1/435 27/18722 0.470163123366431 0.728216262473978 ADRB1 1 GO:0046337 phosphatidylethanolamine metabolic process 1/435 27/18722 0.470163123366431 0.728216262473978 PISD 1 GO:0048520 positive regulation of behavior 1/435 27/18722 0.470163123366431 0.728216262473978 GJA1 1 GO:0060333 interferon-gamma-mediated signaling pathway 1/435 27/18722 0.470163123366431 0.728216262473978 HSP90AB1 1 GO:0060512 prostate gland morphogenesis 1/435 27/18722 0.470163123366431 0.728216262473978 BMP7 1 GO:0061437 renal system vasculature development 1/435 27/18722 0.470163123366431 0.728216262473978 BMP7 1 GO:0061440 kidney vasculature development 1/435 27/18722 0.470163123366431 0.728216262473978 BMP7 1 GO:0071624 positive regulation of granulocyte chemotaxis 1/435 27/18722 0.470163123366431 0.728216262473978 C1QBP 1 GO:0099625 ventricular cardiac muscle cell membrane repolarization 1/435 27/18722 0.470163123366431 0.728216262473978 GJA5 1 GO:1902914 regulation of protein polyubiquitination 1/435 27/18722 0.470163123366431 0.728216262473978 SKP2 1 GO:1903319 positive regulation of protein maturation 1/435 27/18722 0.470163123366431 0.728216262473978 LPCAT3 1 GO:1904357 negative regulation of telomere maintenance via telomere lengthening 1/435 27/18722 0.470163123366431 0.728216262473978 PARP1 1 GO:0009206 purine ribonucleoside triphosphate biosynthetic process 2/435 68/18722 0.471122980018546 0.728216262473978 PARP1/STOML2 2 GO:0010812 negative regulation of cell-substrate adhesion 2/435 68/18722 0.471122980018546 0.728216262473978 FBLN1/TACSTD2 2 GO:0031640 killing of cells of other organism 2/435 68/18722 0.471122980018546 0.728216262473978 RPS19/ROMO1 2 GO:0034394 protein localization to cell surface 2/435 68/18722 0.471122980018546 0.728216262473978 HSP90AB1/UNC50 2 GO:0042267 natural killer cell mediated cytotoxicity 2/435 68/18722 0.471122980018546 0.728216262473978 PRDX1/CADM1 2 GO:0042698 ovulation cycle 2/435 68/18722 0.471122980018546 0.728216262473978 SERPINF1/EGFR 2 GO:0042987 amyloid precursor protein catabolic process 2/435 68/18722 0.471122980018546 0.728216262473978 CLN3/EFNA1 2 GO:1904888 cranial skeletal system development 2/435 68/18722 0.471122980018546 0.728216262473978 SLC39A1/MSX2 2 GO:0090501 RNA phosphodiester bond hydrolysis 4/435 152/18722 0.471977770442663 0.728607623583489 RPS21/NHP2/REXO2/POLR2I 4 GO:0002263 cell activation involved in immune response 7/435 279/18722 0.472157709887267 0.728607623583489 VAMP8/ANXA3/HSPD1/APP/S100A13/LGALS3/CD46 7 GO:0006939 smooth muscle contraction 3/435 110/18722 0.472480960858032 0.728607623583489 SOD1/ATP2B1/CAV1 3 GO:0007088 regulation of mitotic nuclear division 3/435 110/18722 0.472480960858032 0.728607623583489 BMP7/AURKAIP1/LCMT1 3 GO:0014812 muscle cell migration 3/435 110/18722 0.472480960858032 0.728607623583489 GSTP1/S100A11/S1PR2 3 GO:0090174 organelle membrane fusion 3/435 110/18722 0.472480960858032 0.728607623583489 ANXA2/VAMP8/CLN3 3 GO:0001503 ossification 10/435 408/18722 0.476934373979803 0.732624280123804 EGFR/FBN2/BMP7/HSPE1/RRBP1/ATRAID/MSX2/ATP6V1B1/PHB/ATP2B1 10 GO:0001938 positive regulation of endothelial cell proliferation 3/435 111/18722 0.47843690267325 0.732624280123804 NRP2/MYDGF/PDCD6 3 GO:0090288 negative regulation of cellular response to growth factor stimulus 3/435 111/18722 0.47843690267325 0.732624280123804 LRP2/FBN1/PDCD6 3 GO:0009145 purine nucleoside triphosphate biosynthetic process 2/435 69/18722 0.478737503446229 0.732624280123804 PARP1/STOML2 2 GO:0010611 regulation of cardiac muscle hypertrophy 2/435 69/18722 0.478737503446229 0.732624280123804 PARP1/LMNA 2 GO:0031060 regulation of histone methylation 2/435 69/18722 0.478737503446229 0.732624280123804 DNMT1/LMNA 2 GO:0050805 negative regulation of synaptic transmission 2/435 69/18722 0.478737503446229 0.732624280123804 SLC6A4/S1PR2 2 GO:0050810 regulation of steroid biosynthetic process 2/435 69/18722 0.478737503446229 0.732624280123804 SOD1/LPCAT3 2 GO:0051966 regulation of synaptic transmission, glutamatergic 2/435 69/18722 0.478737503446229 0.732624280123804 EGFR/CLN3 2 GO:0006470 protein dephosphorylation 7/435 281/18722 0.479613651008577 0.732624280123804 HSP90B1/DUSP14/HSP90AB1/CTDSPL/SLC39A10/LGALS3/PHPT1 7 GO:0006006 glucose metabolic process 5/435 196/18722 0.47987475319892 0.732624280123804 PHLDA2/DCXR/BAD/DDB1/LCMT1 5 GO:0022408 negative regulation of cell-cell adhesion 5/435 196/18722 0.47987475319892 0.732624280123804 SPINT2/CDH1/PRDX2/LGALS3/ASS1 5 GO:0045664 regulation of neuron differentiation 5/435 196/18722 0.47987475319892 0.732624280123804 BMP7/APP/SLC6A4/CALR/NREP 5 GO:0001945 lymph vessel development 1/435 28/18722 0.482491502148758 0.732624280123804 NR2F2 1 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1/435 28/18722 0.482491502148758 0.732624280123804 CALR 1 GO:0002675 positive regulation of acute inflammatory response 1/435 28/18722 0.482491502148758 0.732624280123804 PARK7 1 GO:0003156 regulation of animal organ formation 1/435 28/18722 0.482491502148758 0.732624280123804 BMP7 1 GO:0006516 glycoprotein catabolic process 1/435 28/18722 0.482491502148758 0.732624280123804 CTSL 1 GO:0010460 positive regulation of heart rate 1/435 28/18722 0.482491502148758 0.732624280123804 ADRB1 1 GO:0010464 regulation of mesenchymal cell proliferation 1/435 28/18722 0.482491502148758 0.732624280123804 LMNA 1 GO:0010884 positive regulation of lipid storage 1/435 28/18722 0.482491502148758 0.732624280123804 HILPDA 1 GO:0019098 reproductive behavior 1/435 28/18722 0.482491502148758 0.732624280123804 APP 1 GO:0031342 negative regulation of cell killing 1/435 28/18722 0.482491502148758 0.732624280123804 HSP90AB1 1 GO:0032607 interferon-alpha production 1/435 28/18722 0.482491502148758 0.732624280123804 HSPD1 1 GO:0032647 regulation of interferon-alpha production 1/435 28/18722 0.482491502148758 0.732624280123804 HSPD1 1 GO:0034123 positive regulation of toll-like receptor signaling pathway 1/435 28/18722 0.482491502148758 0.732624280123804 CAV1 1 GO:0038094 Fc-gamma receptor signaling pathway 1/435 28/18722 0.482491502148758 0.732624280123804 CD47 1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 1/435 28/18722 0.482491502148758 0.732624280123804 EGFR 1 GO:0045589 regulation of regulatory T cell differentiation 1/435 28/18722 0.482491502148758 0.732624280123804 CD46 1 GO:0045671 negative regulation of osteoclast differentiation 1/435 28/18722 0.482491502148758 0.732624280123804 FBN1 1 GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT 1/435 28/18722 0.482491502148758 0.732624280123804 CAV1 1 GO:0051894 positive regulation of focal adhesion assembly 1/435 28/18722 0.482491502148758 0.732624280123804 S100A10 1 GO:0062125 regulation of mitochondrial gene expression 1/435 28/18722 0.482491502148758 0.732624280123804 C1QBP 1 GO:0071280 cellular response to copper ion 1/435 28/18722 0.482491502148758 0.732624280123804 APP 1 GO:0086011 membrane repolarization during action potential 1/435 28/18722 0.482491502148758 0.732624280123804 CAV1 1 GO:0090344 negative regulation of cell aging 1/435 28/18722 0.482491502148758 0.732624280123804 MIF 1 GO:0099623 regulation of cardiac muscle cell membrane repolarization 1/435 28/18722 0.482491502148758 0.732624280123804 GJA5 1 GO:1902624 positive regulation of neutrophil migration 1/435 28/18722 0.482491502148758 0.732624280123804 C1QBP 1 GO:1903649 regulation of cytoplasmic transport 1/435 28/18722 0.482491502148758 0.732624280123804 SNX3 1 GO:1990776 response to angiotensin 1/435 28/18722 0.482491502148758 0.732624280123804 CAV1 1 GO:0002526 acute inflammatory response 3/435 112/18722 0.484361341339901 0.733493236770757 GSTP1/PARK7/ASS1 3 GO:0009141 nucleoside triphosphate metabolic process 3/435 112/18722 0.484361341339901 0.733493236770757 PARP1/STOML2/SMPDL3A 3 GO:0010633 negative regulation of epithelial cell migration 3/435 112/18722 0.484361341339901 0.733493236770757 SERPINF1/NR2F2/TACSTD2 3 GO:0032609 interferon-gamma production 3/435 112/18722 0.484361341339901 0.733493236770757 HSPD1/C1QBP/CD47 3 GO:0032649 regulation of interferon-gamma production 3/435 112/18722 0.484361341339901 0.733493236770757 HSPD1/C1QBP/CD47 3 GO:0035601 protein deacylation 3/435 112/18722 0.484361341339901 0.733493236770757 BEX4/PHB/TBL1X 3 GO:0048640 negative regulation of developmental growth 3/435 112/18722 0.484361341339901 0.733493236770757 GJA1/ADRB1/SLC6A4 3 GO:0050851 antigen receptor-mediated signaling pathway 6/435 240/18722 0.485882495549715 0.735515315566267 RPS3/SLC39A10/LGALS3/STOML2/KCNN4/PHPT1 6 GO:0002548 monocyte chemotaxis 2/435 70/18722 0.486284646598422 0.735842579957919 RPS19/LGALS3 2 GO:1903364 positive regulation of cellular protein catabolic process 4/435 155/18722 0.4870944050877 0.73678614714527 LRP2/BCAP31/PSMC1/CAV1 4 GO:0050900 leukocyte migration 9/435 369/18722 0.488673570857672 0.737328452637204 BSG/PPIB/RPS19/APP/C1QBP/LGALS3/CALR/MIF/CD47 9 GO:0071824 protein-DNA complex subunit organization 6/435 241/18722 0.489901485251088 0.737328452637204 RPL23/HMGA1/GTF2H5/GTF2A2/ZNHIT1/NPM1 6 GO:0002708 positive regulation of lymphocyte mediated immunity 3/435 113/18722 0.490253470674681 0.737328452637204 HSPD1/CADM1/CD55 3 GO:0046631 alpha-beta T cell activation 4/435 156/18722 0.492094552321567 0.737328452637204 CTSL/PNP/CD55/STOML2 4 GO:0000281 mitotic cytokinesis 2/435 71/18722 0.493763425014606 0.737328452637204 MYH10/RHOC 2 GO:0002228 natural killer cell mediated immunity 2/435 71/18722 0.493763425014606 0.737328452637204 PRDX1/CADM1 2 GO:0008344 adult locomotory behavior 2/435 71/18722 0.493763425014606 0.737328452637204 APP/PARK7 2 GO:0050795 regulation of behavior 2/435 71/18722 0.493763425014606 0.737328452637204 GJA1/ADRB1 2 GO:0002068 glandular epithelial cell development 1/435 29/18722 0.494533665225964 0.737328452637204 BAD 1 GO:0002360 T cell lineage commitment 1/435 29/18722 0.494533665225964 0.737328452637204 CTSL 1 GO:0003309 type B pancreatic cell differentiation 1/435 29/18722 0.494533665225964 0.737328452637204 BAD 1 GO:0006656 phosphatidylcholine biosynthetic process 1/435 29/18722 0.494533665225964 0.737328452637204 LPCAT3 1 GO:0006734 NADH metabolic process 1/435 29/18722 0.494533665225964 0.737328452637204 MDH2 1 GO:0010390 histone monoubiquitination 1/435 29/18722 0.494533665225964 0.737328452637204 DDB1 1 GO:0010592 positive regulation of lamellipodium assembly 1/435 29/18722 0.494533665225964 0.737328452637204 WASF2 1 GO:0010955 negative regulation of protein processing 1/435 29/18722 0.494533665225964 0.737328452637204 TMEM59 1 GO:0015701 bicarbonate transport 1/435 29/18722 0.494533665225964 0.737328452637204 CYB5R1 1 GO:0019082 viral protein processing 1/435 29/18722 0.494533665225964 0.737328452637204 SPCS1 1 GO:0019359 nicotinamide nucleotide biosynthetic process 1/435 29/18722 0.494533665225964 0.737328452637204 QPRT 1 GO:0019363 pyridine nucleotide biosynthetic process 1/435 29/18722 0.494533665225964 0.737328452637204 QPRT 1 GO:0021522 spinal cord motor neuron differentiation 1/435 29/18722 0.494533665225964 0.737328452637204 LMO4 1 GO:0021602 cranial nerve morphogenesis 1/435 29/18722 0.494533665225964 0.737328452637204 NRP2 1 GO:0032366 intracellular sterol transport 1/435 29/18722 0.494533665225964 0.737328452637204 ANXA2 1 GO:0032367 intracellular cholesterol transport 1/435 29/18722 0.494533665225964 0.737328452637204 ANXA2 1 GO:0033028 myeloid cell apoptotic process 1/435 29/18722 0.494533665225964 0.737328452637204 CTSL 1 GO:0040018 positive regulation of multicellular organism growth 1/435 29/18722 0.494533665225964 0.737328452637204 PPIB 1 GO:0042759 long-chain fatty acid biosynthetic process 1/435 29/18722 0.494533665225964 0.737328452637204 GSTP1 1 GO:0051873 killing by host of symbiont cells 1/435 29/18722 0.494533665225964 0.737328452637204 ROMO1 1 GO:0051883 killing of cells in other organism involved in symbiotic interaction 1/435 29/18722 0.494533665225964 0.737328452637204 ROMO1 1 GO:0060441 epithelial tube branching involved in lung morphogenesis 1/435 29/18722 0.494533665225964 0.737328452637204 DAG1 1 GO:0060969 negative regulation of gene silencing 1/435 29/18722 0.494533665225964 0.737328452637204 LIN28B 1 GO:0062098 regulation of programmed necrotic cell death 1/435 29/18722 0.494533665225964 0.737328452637204 CAV1 1 GO:0090114 COPII-coated vesicle budding 1/435 29/18722 0.494533665225964 0.737328452637204 PDCD6 1 GO:0095500 acetylcholine receptor signaling pathway 1/435 29/18722 0.494533665225964 0.737328452637204 LY6E 1 GO:1901017 negative regulation of potassium ion transmembrane transporter activity 1/435 29/18722 0.494533665225964 0.737328452637204 CAV1 1 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 1/435 29/18722 0.494533665225964 0.737328452637204 MIF 1 GO:1903318 negative regulation of protein maturation 1/435 29/18722 0.494533665225964 0.737328452637204 TMEM59 1 GO:2000406 positive regulation of T cell migration 1/435 29/18722 0.494533665225964 0.737328452637204 APP 1 GO:0019751 polyol metabolic process 3/435 114/18722 0.496112516668491 0.738569310931985 ISYNA1/NUDT4/AKR1B1 3 GO:1901800 positive regulation of proteasomal protein catabolic process 3/435 114/18722 0.496112516668491 0.738569310931985 BCAP31/PSMC1/CAV1 3 GO:1903008 organelle disassembly 3/435 114/18722 0.496112516668491 0.738569310931985 PARK7/FIS1/BNIP3 3 GO:1904892 regulation of receptor signaling pathway via STAT 3/435 114/18722 0.496112516668491 0.738569310931985 IL10RB/AKR1B1/CAV1 3 GO:0001837 epithelial to mesenchymal transition 4/435 157/18722 0.497074389853469 0.739444872424878 BMP7/EFNA1/DAG1/PDCD6 4 GO:1990845 adaptive thermogenesis 4/435 157/18722 0.497074389853469 0.739444872424878 GNAS/GJA1/ADRB1/CAV1 4 GO:0000271 polysaccharide biosynthetic process 2/435 72/18722 0.501172936069707 0.742101679387526 UGP2/AGL 2 GO:0014743 regulation of muscle hypertrophy 2/435 72/18722 0.501172936069707 0.742101679387526 PARP1/LMNA 2 GO:0030330 DNA damage response, signal transduction by p53 class mediator 2/435 72/18722 0.501172936069707 0.742101679387526 MIF/NPM1 2 GO:0051057 positive regulation of small GTPase mediated signal transduction 2/435 72/18722 0.501172936069707 0.742101679387526 ADGRG1/TGM2 2 GO:0072521 purine-containing compound metabolic process 10/435 416/18722 0.501550749409866 0.742101679387526 PARP1/ACSS1/APP/PNP/TECR/NUDT4/MPC2/BAD/STOML2/TPST2 10 GO:0034968 histone lysine methylation 3/435 115/18722 0.501937736945348 0.742101679387526 DNMT1/LMNA/TRMT112 3 GO:0046916 cellular transition metal ion homeostasis 3/435 115/18722 0.501937736945348 0.742101679387526 SOD1/APP/SLC39A10 3 GO:0019216 regulation of lipid metabolic process 8/435 331/18722 0.505137859471051 0.742101679387526 SOD1/IDH1/ACADVL/STOML2/DNAJC19/CAV1/ORMDL1/LPCAT3 8 GO:0000132 establishment of mitotic spindle orientation 1/435 30/18722 0.506296242427414 0.742101679387526 GJA1 1 GO:0003299 muscle hypertrophy in response to stress 1/435 30/18722 0.506296242427414 0.742101679387526 LMNA 1 GO:0007176 regulation of epidermal growth factor-activated receptor activity 1/435 30/18722 0.506296242427414 0.742101679387526 APP 1 GO:0009072 aromatic amino acid family metabolic process 1/435 30/18722 0.506296242427414 0.742101679387526 PARK7 1 GO:0009264 deoxyribonucleotide catabolic process 1/435 30/18722 0.506296242427414 0.742101679387526 PNP 1 GO:0010453 regulation of cell fate commitment 1/435 30/18722 0.506296242427414 0.742101679387526 LMO4 1 GO:0014887 cardiac muscle adaptation 1/435 30/18722 0.506296242427414 0.742101679387526 LMNA 1 GO:0014898 cardiac muscle hypertrophy in response to stress 1/435 30/18722 0.506296242427414 0.742101679387526 LMNA 1 GO:0019674 NAD metabolic process 1/435 30/18722 0.506296242427414 0.742101679387526 QPRT 1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 1/435 30/18722 0.506296242427414 0.742101679387526 CTSL 1 GO:0030204 chondroitin sulfate metabolic process 1/435 30/18722 0.506296242427414 0.742101679387526 CHPF 1 GO:0031571 mitotic G1 DNA damage checkpoint signaling 1/435 30/18722 0.506296242427414 0.742101679387526 CCND1 1 GO:0033137 negative regulation of peptidyl-serine phosphorylation 1/435 30/18722 0.506296242427414 0.742101679387526 CAV1 1 GO:0034390 smooth muscle cell apoptotic process 1/435 30/18722 0.506296242427414 0.742101679387526 DNMT1 1 GO:0034391 regulation of smooth muscle cell apoptotic process 1/435 30/18722 0.506296242427414 0.742101679387526 DNMT1 1 GO:0043032 positive regulation of macrophage activation 1/435 30/18722 0.506296242427414 0.742101679387526 HSPD1 1 GO:0043304 regulation of mast cell degranulation 1/435 30/18722 0.506296242427414 0.742101679387526 VAMP8 1 GO:0044030 regulation of DNA methylation 1/435 30/18722 0.506296242427414 0.742101679387526 PARP1 1 GO:0045577 regulation of B cell differentiation 1/435 30/18722 0.506296242427414 0.742101679387526 BAD 1 GO:0045939 negative regulation of steroid metabolic process 1/435 30/18722 0.506296242427414 0.742101679387526 SOD1 1 GO:0046825 regulation of protein export from nucleus 1/435 30/18722 0.506296242427414 0.742101679387526 PARK7 1 GO:0048147 negative regulation of fibroblast proliferation 1/435 30/18722 0.506296242427414 0.742101679387526 GSTP1 1 GO:0051125 regulation of actin nucleation 1/435 30/18722 0.506296242427414 0.742101679387526 WASF2 1 GO:0051968 positive regulation of synaptic transmission, glutamatergic 1/435 30/18722 0.506296242427414 0.742101679387526 EGFR 1 GO:0061311 cell surface receptor signaling pathway involved in heart development 1/435 30/18722 0.506296242427414 0.742101679387526 GALNT11 1 GO:0061384 heart trabecula morphogenesis 1/435 30/18722 0.506296242427414 0.742101679387526 BMP7 1 GO:0090314 positive regulation of protein targeting to membrane 1/435 30/18722 0.506296242427414 0.742101679387526 FIS1 1 GO:0140058 neuron projection arborization 1/435 30/18722 0.506296242427414 0.742101679387526 LRP2 1 GO:1903019 negative regulation of glycoprotein metabolic process 1/435 30/18722 0.506296242427414 0.742101679387526 TMEM59 1 GO:2000637 positive regulation of gene silencing by miRNA 1/435 30/18722 0.506296242427414 0.742101679387526 EGFR 1 GO:2000648 positive regulation of stem cell proliferation 1/435 30/18722 0.506296242427414 0.742101679387526 GJA1 1 GO:0016051 carbohydrate biosynthetic process 5/435 202/18722 0.506362025359191 0.742101679387526 ISYNA1/UGP2/AGL/AKR1B1/DDB1 5 GO:0032200 telomere organization 4/435 159/18722 0.506970978472926 0.742719052875738 PKIB/PARP1/HSP90AB1/NHP2 4 GO:0018107 peptidyl-threonine phosphorylation 3/435 116/18722 0.507728420217162 0.742728783289948 BMP7/APP/S1PR2 3 GO:0031123 RNA 3'-end processing 3/435 116/18722 0.507728420217162 0.742728783289948 RPS21/APP/LIN28B 3 GO:0035967 cellular response to topologically incorrect protein 3/435 116/18722 0.507728420217162 0.742728783289948 HSPD1/CCND1/ERLEC1 3 GO:0098732 macromolecule deacylation 3/435 116/18722 0.507728420217162 0.742728783289948 BEX4/PHB/TBL1X 3 GO:0009166 nucleotide catabolic process 2/435 73/18722 0.508512355718641 0.74277718404528 PNP/NUDT4 2 GO:0032732 positive regulation of interleukin-1 production 2/435 73/18722 0.508512355718641 0.74277718404528 APP/S100A13 2 GO:0042058 regulation of epidermal growth factor receptor signaling pathway 2/435 73/18722 0.508512355718641 0.74277718404528 IFI6/EGFR 2 GO:0051937 catecholamine transport 2/435 73/18722 0.508512355718641 0.74277718404528 PARK7/LY6E 2 GO:0060541 respiratory system development 5/435 203/18722 0.510725507724435 0.743964435687563 EGFR/MME/DAG1/ASS1/LAMA5 5 GO:0023061 signal release 11/435 463/18722 0.513103446306249 0.743964435687563 FAM3B/EGFR/VAMP8/WLS/GJA1/SLC6A4/PARK7/MPC2/HMGN3/BAD/PHPT1 11 GO:0030301 cholesterol transport 3/435 117/18722 0.513483885735126 0.743964435687563 ANXA2/CAV1/LPCAT3 3 GO:1901888 regulation of cell junction assembly 5/435 204/18722 0.515073344320476 0.743964435687563 APP/GJA1/S100A10/CAV1/RAB17 5 GO:0009201 ribonucleoside triphosphate biosynthetic process 2/435 74/18722 0.51578093534737 0.743964435687563 PARP1/STOML2 2 GO:0030968 endoplasmic reticulum unfolded protein response 2/435 74/18722 0.51578093534737 0.743964435687563 CCND1/ERLEC1 2 GO:0046470 phosphatidylcholine metabolic process 2/435 74/18722 0.51578093534737 0.743964435687563 DBI/LPCAT3 2 GO:0002429 immune response-activating cell surface receptor signaling pathway 7/435 291/18722 0.516426063864081 0.743964435687563 RPS3/SLC39A10/LGALS3/STOML2/KCNN4/PHPT1/CD47 7 GO:0002757 immune response-activating signal transduction 7/435 291/18722 0.516426063864081 0.743964435687563 RPS3/SLC39A10/LGALS3/STOML2/KCNN4/PHPT1/CD47 7 GO:0060485 mesenchyme development 7/435 291/18722 0.516426063864081 0.743964435687563 NRP2/FOLR1/BMP7/EFNA1/DAG1/LAMA5/PDCD6 7 GO:0051650 establishment of vesicle localization 4/435 161/18722 0.516780009601132 0.743964435687563 CLN3/TMED9/PDCD6/RAB17 4 GO:0018212 peptidyl-tyrosine modification 9/435 378/18722 0.517689596295668 0.743964435687563 EFEMP1/CD24/EGFR/MET/APP/EFNA1/MIF/TPST2/CAV1 9 GO:0021537 telencephalon development 6/435 248/18722 0.517732944736822 0.743964435687563 ADGRG1/SLC2A1/UQCRQ/ANXA3/BAD/BNIP3 6 GO:0001516 prostaglandin biosynthetic process 1/435 31/18722 0.517785710357228 0.743964435687563 MIF 1 GO:0002717 positive regulation of natural killer cell mediated immunity 1/435 31/18722 0.517785710357228 0.743964435687563 CADM1 1 GO:0006779 porphyrin-containing compound biosynthetic process 1/435 31/18722 0.517785710357228 0.743964435687563 TMEM14C 1 GO:0018200 peptidyl-glutamic acid modification 1/435 31/18722 0.517785710357228 0.743964435687563 PARP1 1 GO:0030201 heparan sulfate proteoglycan metabolic process 1/435 31/18722 0.517785710357228 0.743964435687563 EXTL2 1 GO:0030212 hyaluronan metabolic process 1/435 31/18722 0.517785710357228 0.743964435687563 ITIH5 1 GO:0032148 activation of protein kinase B activity 1/435 31/18722 0.517785710357228 0.743964435687563 PARK7 1 GO:0033006 regulation of mast cell activation involved in immune response 1/435 31/18722 0.517785710357228 0.743964435687563 VAMP8 1 GO:0033014 tetrapyrrole biosynthetic process 1/435 31/18722 0.517785710357228 0.743964435687563 TMEM14C 1 GO:0034656 nucleobase-containing small molecule catabolic process 1/435 31/18722 0.517785710357228 0.743964435687563 PNP 1 GO:0044819 mitotic G1/S transition checkpoint signaling 1/435 31/18722 0.517785710357228 0.743964435687563 CCND1 1 GO:0045066 regulatory T cell differentiation 1/435 31/18722 0.517785710357228 0.743964435687563 CD46 1 GO:0046386 deoxyribose phosphate catabolic process 1/435 31/18722 0.517785710357228 0.743964435687563 PNP 1 GO:0046457 prostanoid biosynthetic process 1/435 31/18722 0.517785710357228 0.743964435687563 MIF 1 GO:0048384 retinoic acid receptor signaling pathway 1/435 31/18722 0.517785710357228 0.743964435687563 CALR 1 GO:0051569 regulation of histone H3-K4 methylation 1/435 31/18722 0.517785710357228 0.743964435687563 DNMT1 1 GO:0055022 negative regulation of cardiac muscle tissue growth 1/435 31/18722 0.517785710357228 0.743964435687563 GJA1 1 GO:0055075 potassium ion homeostasis 1/435 31/18722 0.517785710357228 0.743964435687563 ATP6V1B1 1 GO:0060055 angiogenesis involved in wound healing 1/435 31/18722 0.517785710357228 0.743964435687563 DAG1 1 GO:0060148 positive regulation of posttranscriptional gene silencing 1/435 31/18722 0.517785710357228 0.743964435687563 EGFR 1 GO:0060390 regulation of SMAD protein signal transduction 1/435 31/18722 0.517785710357228 0.743964435687563 PARP1 1 GO:0061099 negative regulation of protein tyrosine kinase activity 1/435 31/18722 0.517785710357228 0.743964435687563 CAV1 1 GO:0061117 negative regulation of heart growth 1/435 31/18722 0.517785710357228 0.743964435687563 GJA1 1 GO:0065005 protein-lipid complex assembly 1/435 31/18722 0.517785710357228 0.743964435687563 LPCAT3 1 GO:0070528 protein kinase C signaling 1/435 31/18722 0.517785710357228 0.743964435687563 ADGRG1 1 GO:0070723 response to cholesterol 1/435 31/18722 0.517785710357228 0.743964435687563 DAG1 1 GO:0071480 cellular response to gamma radiation 1/435 31/18722 0.517785710357228 0.743964435687563 GTF2H5 1 GO:0090162 establishment of epithelial cell polarity 1/435 31/18722 0.517785710357228 0.743964435687563 FERMT1 1 GO:1901797 negative regulation of signal transduction by p53 class mediator 1/435 31/18722 0.517785710357228 0.743964435687563 MIF 1 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 1/435 31/18722 0.517785710357228 0.743964435687563 PARK7 1 GO:1905144 response to acetylcholine 1/435 31/18722 0.517785710357228 0.743964435687563 LY6E 1 GO:1905145 cellular response to acetylcholine 1/435 31/18722 0.517785710357228 0.743964435687563 LY6E 1 GO:0007613 memory 3/435 118/18722 0.519203482738448 0.744919572587396 SERPINF1/COMT/SLC6A4 3 GO:0030203 glycosaminoglycan metabolic process 3/435 118/18722 0.519203482738448 0.744919572587396 ITIH5/FUCA1/CHPF 3 GO:0045446 endothelial cell differentiation 3/435 118/18722 0.519203482738448 0.744919572587396 MET/NR2F2/S1PR2 3 GO:0071346 cellular response to interferon-gamma 3/435 118/18722 0.519203482738448 0.744919572587396 HSP90AB1/ASS1/CD47 3 GO:0021953 central nervous system neuron differentiation 4/435 162/18722 0.521650457119707 0.747633726715406 LMO4/NRP2/UQCRQ/HSP90AB1 4 GO:0060759 regulation of response to cytokine stimulus 4/435 162/18722 0.521650457119707 0.747633726715406 CD24/GSTP1/HSP90AB1/CAV1 4 GO:0045926 negative regulation of growth 6/435 249/18722 0.521662046869153 0.747633726715406 NDUFA13/GJA1/ADRB1/SLC6A4/PHB/RBBP7 6 GO:0008088 axo-dendritic transport 2/435 75/18722 0.522977998727305 0.748977177330418 SOD1/APP 2 GO:0045913 positive regulation of carbohydrate metabolic process 2/435 75/18722 0.522977998727305 0.748977177330418 APP/DDB1 2 GO:0030099 myeloid cell differentiation 9/435 381/18722 0.527246889102404 0.75028180024561 ANXA2/RPS14/RPS19/PARP1/APP/FBN1/TMEM14C/WASF2/PRMT1 9 GO:0003180 aortic valve morphogenesis 1/435 32/18722 0.529008395927534 0.75028180024561 EFNA1 1 GO:0006026 aminoglycan catabolic process 1/435 32/18722 0.529008395927534 0.75028180024561 FUCA1 1 GO:0006506 GPI anchor biosynthetic process 1/435 32/18722 0.529008395927534 0.75028180024561 PYURF 1 GO:0008156 negative regulation of DNA replication 1/435 32/18722 0.529008395927534 0.75028180024561 S100A11 1 GO:0010039 response to iron ion 1/435 32/18722 0.529008395927534 0.75028180024561 CCND1 1 GO:0019835 cytolysis 1/435 32/18722 0.529008395927534 0.75028180024561 ROMO1 1 GO:0021799 cerebral cortex radially oriented cell migration 1/435 32/18722 0.529008395927534 0.75028180024561 ADGRG1 1 GO:0030431 sleep 1/435 32/18722 0.529008395927534 0.75028180024561 ADRB1 1 GO:0032196 transposition 1/435 32/18722 0.529008395927534 0.75028180024561 L1TD1 1 GO:0033687 osteoblast proliferation 1/435 32/18722 0.529008395927534 0.75028180024561 ATRAID 1 GO:0035456 response to interferon-beta 1/435 32/18722 0.529008395927534 0.75028180024561 NDUFA13 1 GO:0035767 endothelial cell chemotaxis 1/435 32/18722 0.529008395927534 0.75028180024561 MET 1 GO:0035883 enteroendocrine cell differentiation 1/435 32/18722 0.529008395927534 0.75028180024561 BAD 1 GO:0046475 glycerophospholipid catabolic process 1/435 32/18722 0.529008395927534 0.75028180024561 PRDX6 1 GO:0050685 positive regulation of mRNA processing 1/435 32/18722 0.529008395927534 0.75028180024561 PRDX6 1 GO:0060317 cardiac epithelial to mesenchymal transition 1/435 32/18722 0.529008395927534 0.75028180024561 EFNA1 1 GO:0061037 negative regulation of cartilage development 1/435 32/18722 0.529008395927534 0.75028180024561 EFEMP1 1 GO:0071875 adrenergic receptor signaling pathway 1/435 32/18722 0.529008395927534 0.75028180024561 ADRB1 1 GO:0072525 pyridine-containing compound biosynthetic process 1/435 32/18722 0.529008395927534 0.75028180024561 QPRT 1 GO:0090022 regulation of neutrophil chemotaxis 1/435 32/18722 0.529008395927534 0.75028180024561 C1QBP 1 GO:0097345 mitochondrial outer membrane permeabilization 1/435 32/18722 0.529008395927534 0.75028180024561 BNIP3 1 GO:1900745 positive regulation of p38MAPK cascade 1/435 32/18722 0.529008395927534 0.75028180024561 PRMT1 1 GO:1901185 negative regulation of ERBB signaling pathway 1/435 32/18722 0.529008395927534 0.75028180024561 EGFR 1 GO:1903955 positive regulation of protein targeting to mitochondrion 1/435 32/18722 0.529008395927534 0.75028180024561 PDCD5 1 GO:1905476 negative regulation of protein localization to membrane 1/435 32/18722 0.529008395927534 0.75028180024561 TMEM59 1 GO:2000191 regulation of fatty acid transport 1/435 32/18722 0.529008395927534 0.75028180024561 FIS1 1 GO:0006305 DNA alkylation 2/435 76/18722 0.530102939069973 0.750757813135248 DNMT1/PARP1 2 GO:0006306 DNA methylation 2/435 76/18722 0.530102939069973 0.750757813135248 DNMT1/PARP1 2 GO:0045685 regulation of glial cell differentiation 2/435 76/18722 0.530102939069973 0.750757813135248 SPINT1/DAG1 2 GO:0140115 export across plasma membrane 2/435 76/18722 0.530102939069973 0.750757813135248 GJA1/ATP2B1 2 GO:0050806 positive regulation of synaptic transmission 4/435 164/18722 0.531320878904902 0.75221349475016 EGFR/MME/APP/NSG1 4 GO:0002224 toll-like receptor signaling pathway 3/435 121/18722 0.536140993245559 0.755004660286189 COLEC12/HSPD1/CAV1 3 GO:0002455 humoral immune response mediated by circulating immunoglobulin 3/435 121/18722 0.536140993245559 0.755004660286189 C1QBP/CD46/CD55 3 GO:0038127 ERBB signaling pathway 3/435 121/18722 0.536140993245559 0.755004660286189 EFEMP1/IFI6/EGFR 3 GO:0042752 regulation of circadian rhythm 3/435 121/18722 0.536140993245559 0.755004660286189 MAGED1/ADRB1/DDB1 3 GO:0043244 regulation of protein-containing complex disassembly 3/435 121/18722 0.536140993245559 0.755004660286189 CLN3/DSTN/BNIP3 3 GO:0043500 muscle adaptation 3/435 121/18722 0.536140993245559 0.755004660286189 PARP1/DAG1/LMNA 3 GO:0045931 positive regulation of mitotic cell cycle 3/435 121/18722 0.536140993245559 0.755004660286189 EGFR/APP/CCND1 3 GO:1904019 epithelial cell apoptotic process 3/435 121/18722 0.536140993245559 0.755004660286189 KRT18/KRT8/BAD 3 GO:0021675 nerve development 2/435 77/18722 0.537155216178942 0.755004660286189 NRP2/DAG1 2 GO:0032418 lysosome localization 2/435 77/18722 0.537155216178942 0.755004660286189 VAMP8/S100A13 2 GO:0140056 organelle localization by membrane tethering 2/435 77/18722 0.537155216178942 0.755004660286189 VAMP8/CLN3 2 GO:0045786 negative regulation of cell cycle 9/435 385/18722 0.539887864043079 0.755004660286189 EGFR/CDKN1C/BMP7/AURKAIP1/CTDSPL/NR2F2/NPM1/CCND1/LCMT1 9 GO:0001975 response to amphetamine 1/435 33/18722 0.539970479810441 0.755004660286189 SOD1 1 GO:0002431 Fc receptor mediated stimulatory signaling pathway 1/435 33/18722 0.539970479810441 0.755004660286189 CD47 1 GO:0006505 GPI anchor metabolic process 1/435 33/18722 0.539970479810441 0.755004660286189 PYURF 1 GO:0010165 response to X-ray 1/435 33/18722 0.539970479810441 0.755004660286189 CCND1 1 GO:0010737 protein kinase A signaling 1/435 33/18722 0.539970479810441 0.755004660286189 MIF 1 GO:0019362 pyridine nucleotide metabolic process 1/435 33/18722 0.539970479810441 0.755004660286189 QPRT 1 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 1/435 33/18722 0.539970479810441 0.755004660286189 PDCD6 1 GO:0032228 regulation of synaptic transmission, GABAergic 1/435 33/18722 0.539970479810441 0.755004660286189 CLN3 1 GO:0035025 positive regulation of Rho protein signal transduction 1/435 33/18722 0.539970479810441 0.755004660286189 ADGRG1 1 GO:0040020 regulation of meiotic nuclear division 1/435 33/18722 0.539970479810441 0.755004660286189 CALR 1 GO:0045648 positive regulation of erythrocyte differentiation 1/435 33/18722 0.539970479810441 0.755004660286189 PRMT1 1 GO:0046320 regulation of fatty acid oxidation 1/435 33/18722 0.539970479810441 0.755004660286189 ACADVL 1 GO:0046496 nicotinamide nucleotide metabolic process 1/435 33/18722 0.539970479810441 0.755004660286189 QPRT 1 GO:0046685 response to arsenic-containing substance 1/435 33/18722 0.539970479810441 0.755004660286189 SERPINF1 1 GO:0060122 inner ear receptor cell stereocilium organization 1/435 33/18722 0.539970479810441 0.755004660286189 SOD1 1 GO:0099174 regulation of presynapse organization 1/435 33/18722 0.539970479810441 0.755004660286189 APP 1 GO:0120033 negative regulation of plasma membrane bounded cell projection assembly 1/435 33/18722 0.539970479810441 0.755004660286189 TACSTD2 1 GO:0150117 positive regulation of cell-substrate junction organization 1/435 33/18722 0.539970479810441 0.755004660286189 S100A10 1 GO:1901380 negative regulation of potassium ion transmembrane transport 1/435 33/18722 0.539970479810441 0.755004660286189 CAV1 1 GO:1901976 regulation of cell cycle checkpoint 1/435 33/18722 0.539970479810441 0.755004660286189 LCMT1 1 GO:1902275 regulation of chromatin organization 1/435 33/18722 0.539970479810441 0.755004660286189 DNMT1 1 GO:1905606 regulation of presynapse assembly 1/435 33/18722 0.539970479810441 0.755004660286189 APP 1 GO:2000036 regulation of stem cell population maintenance 1/435 33/18722 0.539970479810441 0.755004660286189 BMP7 1 GO:0060538 skeletal muscle organ development 4/435 166/18722 0.540894391627071 0.756029356294002 NR2F2/DAG1/ASS1/CAV1 4 GO:0002688 regulation of leukocyte chemotaxis 3/435 122/18722 0.541711188954512 0.756636489478646 C1QBP/CALR/MIF 3 GO:0051928 positive regulation of calcium ion transport 3/435 122/18722 0.541711188954512 0.756636489478646 LGALS3/ATP2B1/CAV1 3 GO:0008306 associative learning 2/435 78/18722 0.544134353696096 0.758949466893004 APP/CLN3 2 GO:0009064 glutamine family amino acid metabolic process 2/435 78/18722 0.544134353696096 0.758949466893004 CLN3/ASS1 2 GO:0019319 hexose biosynthetic process 2/435 78/18722 0.544134353696096 0.758949466893004 AKR1B1/DDB1 2 GO:0061045 negative regulation of wound healing 2/435 78/18722 0.544134353696096 0.758949466893004 ANXA2/GJA1 2 GO:0046474 glycerophospholipid biosynthetic process 5/435 211/18722 0.545039611531051 0.759944236373632 TMEM150A/CLN3/PISD/PYURF/LPCAT3 5 GO:0032496 response to lipopolysaccharide 8/435 343/18722 0.54561465006548 0.760478045195176 GSTP1/COMT/PRDX2/HSPD1/GJA1/ADH5/ASS1/CD55 8 GO:0002706 regulation of lymphocyte mediated immunity 4/435 168/18722 0.550367663683912 0.761069817972369 HSPD1/CD46/CADM1/CD55 4 GO:0001662 behavioral fear response 1/435 34/18722 0.550677999810572 0.761069817972369 GJA1 1 GO:0002446 neutrophil mediated immunity 1/435 34/18722 0.550677999810572 0.761069817972369 ANXA3 1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 1/435 34/18722 0.550677999810572 0.761069817972369 CTSL 1 GO:0006356 regulation of transcription by RNA polymerase I 1/435 34/18722 0.550677999810572 0.761069817972369 POLR2L 1 GO:0010614 negative regulation of cardiac muscle hypertrophy 1/435 34/18722 0.550677999810572 0.761069817972369 LMNA 1 GO:0010661 positive regulation of muscle cell apoptotic process 1/435 34/18722 0.550677999810572 0.761069817972369 BNIP3 1 GO:0019076 viral release from host cell 1/435 34/18722 0.550677999810572 0.761069817972369 DDB1 1 GO:0019320 hexose catabolic process 1/435 34/18722 0.550677999810572 0.761069817972369 BAD 1 GO:0032212 positive regulation of telomere maintenance via telomerase 1/435 34/18722 0.550677999810572 0.761069817972369 PKIB 1 GO:0032770 positive regulation of monooxygenase activity 1/435 34/18722 0.550677999810572 0.761069817972369 PARK7 1 GO:0035308 negative regulation of protein dephosphorylation 1/435 34/18722 0.550677999810572 0.761069817972369 LGALS3 1 GO:0035890 exit from host 1/435 34/18722 0.550677999810572 0.761069817972369 DDB1 1 GO:0035891 exit from host cell 1/435 34/18722 0.550677999810572 0.761069817972369 DDB1 1 GO:0043276 anoikis 1/435 34/18722 0.550677999810572 0.761069817972369 CAV1 1 GO:0048261 negative regulation of receptor-mediated endocytosis 1/435 34/18722 0.550677999810572 0.761069817972369 LRPAP1 1 GO:0048854 brain morphogenesis 1/435 34/18722 0.550677999810572 0.761069817972369 SLC6A4 1 GO:0051085 chaperone cofactor-dependent protein refolding 1/435 34/18722 0.550677999810572 0.761069817972369 HSPE1 1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 1/435 34/18722 0.550677999810572 0.761069817972369 TGM2 1 GO:0070050 neuron cellular homeostasis 1/435 34/18722 0.550677999810572 0.761069817972369 ATP2B1 1 GO:0090075 relaxation of muscle 1/435 34/18722 0.550677999810572 0.761069817972369 SOD1 1 GO:1904893 negative regulation of receptor signaling pathway via STAT 1/435 34/18722 0.550677999810572 0.761069817972369 CAV1 1 GO:0006029 proteoglycan metabolic process 2/435 79/18722 0.551039936439433 0.761069817972369 EXTL2/CHPF 2 GO:0060420 regulation of heart growth 2/435 79/18722 0.551039936439433 0.761069817972369 DUSP9/GJA1 2 GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 2/435 79/18722 0.551039936439433 0.761069817972369 RPS19/ROMO1 2 GO:1901184 regulation of ERBB signaling pathway 2/435 79/18722 0.551039936439433 0.761069817972369 IFI6/EGFR 2 GO:0031214 biomineral tissue development 4/435 169/18722 0.555065730406517 0.76636255939239 FBN2/BMP7/ATRAID/ATP2B1 4 GO:0031348 negative regulation of defense response 6/435 258/18722 0.556423942903223 0.767514183170129 SERPINF1/GSTP1/SOD1/RPS19/C1QBP/LPCAT3 6 GO:0001570 vasculogenesis 2/435 80/18722 0.557871607829628 0.767514183170129 AMOT/CAV1 2 GO:0009791 post-embryonic development 2/435 80/18722 0.557871607829628 0.767514183170129 EFEMP1/FBN1 2 GO:0021766 hippocampus development 2/435 80/18722 0.557871607829628 0.767514183170129 UQCRQ/ANXA3 2 GO:0032204 regulation of telomere maintenance 2/435 80/18722 0.557871607829628 0.767514183170129 PKIB/PARP1 2 GO:0051053 negative regulation of DNA metabolic process 3/435 125/18722 0.558187720895218 0.767514183170129 PARP1/GJA1/RPS3 3 GO:2000027 regulation of animal organ morphogenesis 3/435 125/18722 0.558187720895218 0.767514183170129 MAGED1/BMP7/TACSTD2 3 GO:0007162 negative regulation of cell adhesion 7/435 303/18722 0.559307176777548 0.767514183170129 SPINT2/CDH1/FBLN1/PRDX2/LGALS3/ASS1/TACSTD2 7 GO:0000460 maturation of 5.8S rRNA 1/435 35/18722 0.561136854160016 0.767514183170129 RPS21 1 GO:0002209 behavioral defense response 1/435 35/18722 0.561136854160016 0.767514183170129 GJA1 1 GO:0006471 protein ADP-ribosylation 1/435 35/18722 0.561136854160016 0.767514183170129 PARP1 1 GO:0006691 leukotriene metabolic process 1/435 35/18722 0.561136854160016 0.767514183170129 MGST3 1 GO:0009119 ribonucleoside metabolic process 1/435 35/18722 0.561136854160016 0.767514183170129 PNP 1 GO:0010664 negative regulation of striated muscle cell apoptotic process 1/435 35/18722 0.561136854160016 0.767514183170129 BMP7 1 GO:0019068 virion assembly 1/435 35/18722 0.561136854160016 0.767514183170129 SPCS1 1 GO:0021955 central nervous system neuron axonogenesis 1/435 35/18722 0.561136854160016 0.767514183170129 HSP90AB1 1 GO:0031076 embryonic camera-type eye development 1/435 35/18722 0.561136854160016 0.767514183170129 BMP7 1 GO:0032205 negative regulation of telomere maintenance 1/435 35/18722 0.561136854160016 0.767514183170129 PARP1 1 GO:0039694 viral RNA genome replication 1/435 35/18722 0.561136854160016 0.767514183170129 PHB 1 GO:0040001 establishment of mitotic spindle localization 1/435 35/18722 0.561136854160016 0.767514183170129 GJA1 1 GO:0044273 sulfur compound catabolic process 1/435 35/18722 0.561136854160016 0.767514183170129 CDO1 1 GO:0045922 negative regulation of fatty acid metabolic process 1/435 35/18722 0.561136854160016 0.767514183170129 ACADVL 1 GO:0046640 regulation of alpha-beta T cell proliferation 1/435 35/18722 0.561136854160016 0.767514183170129 CD55 1 GO:0050654 chondroitin sulfate proteoglycan metabolic process 1/435 35/18722 0.561136854160016 0.767514183170129 CHPF 1 GO:0071108 protein K48-linked deubiquitination 1/435 35/18722 0.561136854160016 0.767514183170129 PARK7 1 GO:1905207 regulation of cardiocyte differentiation 1/435 35/18722 0.561136854160016 0.767514183170129 EGFR 1 GO:2000403 positive regulation of lymphocyte migration 1/435 35/18722 0.561136854160016 0.767514183170129 APP 1 GO:0031669 cellular response to nutrient levels 5/435 215/18722 0.561765530844116 0.768108571371861 SLC2A1/COMT/FOLR1/ATP2B1/TXN2 5 GO:0031929 TOR signaling 3/435 126/18722 0.563600358026952 0.769895664959496 LAMTOR5/SLC38A9/PDCD6 3 GO:0032874 positive regulation of stress-activated MAPK cascade 3/435 126/18722 0.563600358026952 0.769895664959496 ARL6IP5/APP/PRMT1 3 GO:0006260 DNA replication 6/435 260/18722 0.563990666517675 0.769895664959496 EGFR/S100A11/HMGA1/SSBP1/RBBP7/STOML2 6 GO:0051048 negative regulation of secretion 4/435 171/18722 0.564382888749931 0.769895664959496 COMT/VAMP8/GJA1/ERP29 4 GO:0110148 biomineralization 4/435 171/18722 0.564382888749931 0.769895664959496 FBN2/BMP7/ATRAID/ATP2B1 4 GO:0001960 negative regulation of cytokine-mediated signaling pathway 2/435 81/18722 0.564629067402693 0.769895664959496 GSTP1/CAV1 2 GO:0048708 astrocyte differentiation 2/435 81/18722 0.564629067402693 0.769895664959496 EGFR/APP 2 GO:2001021 negative regulation of response to DNA damage stimulus 2/435 81/18722 0.564629067402693 0.769895664959496 RPS3/MIF 2 GO:0035270 endocrine system development 3/435 127/18722 0.568972527791376 0.770829542565996 CDH1/LY6E/BAD 3 GO:1901136 carbohydrate derivative catabolic process 4/435 172/18722 0.569001286681829 0.770829542565996 CTSL/PNP/FUCA1/NUDT4 4 GO:0009205 purine ribonucleoside triphosphate metabolic process 2/435 82/18722 0.571312068406136 0.770829542565996 PARP1/STOML2 2 GO:0016575 histone deacetylation 2/435 82/18722 0.571312068406136 0.770829542565996 PHB/TBL1X 2 GO:0046364 monosaccharide biosynthetic process 2/435 82/18722 0.571312068406136 0.770829542565996 AKR1B1/DDB1 2 GO:0060395 SMAD protein signal transduction 2/435 82/18722 0.571312068406136 0.770829542565996 BMP7/PARP1 2 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 1/435 36/18722 0.571352804737444 0.770829542565996 CTSL 1 GO:0002691 regulation of cellular extravasation 1/435 36/18722 0.571352804737444 0.770829542565996 CD47 1 GO:0003203 endocardial cushion morphogenesis 1/435 36/18722 0.571352804737444 0.770829542565996 BMP7 1 GO:0003230 cardiac atrium development 1/435 36/18722 0.571352804737444 0.770829542565996 GJA5 1 GO:0006699 bile acid biosynthetic process 1/435 36/18722 0.571352804737444 0.770829542565996 SLC27A2 1 GO:0007031 peroxisome organization 1/435 36/18722 0.571352804737444 0.770829542565996 FIS1 1 GO:0008207 C21-steroid hormone metabolic process 1/435 36/18722 0.571352804737444 0.770829542565996 AKR1B1 1 GO:0010092 specification of animal organ identity 1/435 36/18722 0.571352804737444 0.770829542565996 LRP2 1 GO:0010762 regulation of fibroblast migration 1/435 36/18722 0.571352804737444 0.770829542565996 CLN3 1 GO:0010923 negative regulation of phosphatase activity 1/435 36/18722 0.571352804737444 0.770829542565996 LGALS3 1 GO:0014741 negative regulation of muscle hypertrophy 1/435 36/18722 0.571352804737444 0.770829542565996 LMNA 1 GO:0036314 response to sterol 1/435 36/18722 0.571352804737444 0.770829542565996 DAG1 1 GO:0042119 neutrophil activation 1/435 36/18722 0.571352804737444 0.770829542565996 ANXA3 1 GO:0044060 regulation of endocrine process 1/435 36/18722 0.571352804737444 0.770829542565996 GJA1 1 GO:0045652 regulation of megakaryocyte differentiation 1/435 36/18722 0.571352804737444 0.770829542565996 PRMT1 1 GO:0045738 negative regulation of DNA repair 1/435 36/18722 0.571352804737444 0.770829542565996 RPS3 1 GO:0045746 negative regulation of Notch signaling pathway 1/435 36/18722 0.571352804737444 0.770829542565996 BMP7 1 GO:0046466 membrane lipid catabolic process 1/435 36/18722 0.571352804737444 0.770829542565996 FUCA1 1 GO:0051354 negative regulation of oxidoreductase activity 1/435 36/18722 0.571352804737444 0.770829542565996 CAV1 1 GO:0060251 regulation of glial cell proliferation 1/435 36/18722 0.571352804737444 0.770829542565996 EGFR 1 GO:0060338 regulation of type I interferon-mediated signaling pathway 1/435 36/18722 0.571352804737444 0.770829542565996 HSP90AB1 1 GO:0070873 regulation of glycogen metabolic process 1/435 36/18722 0.571352804737444 0.770829542565996 PHLDA2 1 GO:0070897 transcription preinitiation complex assembly 1/435 36/18722 0.571352804737444 0.770829542565996 GTF2A2 1 GO:0090313 regulation of protein targeting to membrane 1/435 36/18722 0.571352804737444 0.770829542565996 FIS1 1 GO:1903749 positive regulation of establishment of protein localization to mitochondrion 1/435 36/18722 0.571352804737444 0.770829542565996 PDCD5 1 GO:0042445 hormone metabolic process 5/435 218/18722 0.574105322935034 0.773492283821995 CTSL/COMT/HSD17B1/MME/AKR1B1 5 GO:0001952 regulation of cell-matrix adhesion 3/435 128/18722 0.57430384884231 0.773492283821995 S100A10/DAG1/FERMT1 3 GO:0032612 interleukin-1 production 3/435 128/18722 0.57430384884231 0.773492283821995 GSTP1/APP/S100A13 3 GO:0032652 regulation of interleukin-1 production 3/435 128/18722 0.57430384884231 0.773492283821995 GSTP1/APP/S100A13 3 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 3/435 128/18722 0.57430384884231 0.773492283821995 ARL6IP5/APP/PRMT1 3 GO:0046785 microtubule polymerization 2/435 83/18722 0.5779204154761 0.776351220790911 MET/RPS3 2 GO:0050886 endocrine process 2/435 83/18722 0.5779204154761 0.776351220790911 MME/GJA1 2 GO:2001020 regulation of response to DNA damage stimulus 5/435 219/18722 0.578178156506604 0.776351220790911 EGFR/PARP1/RPS3/MIF/NPM1 5 GO:0032868 response to insulin 6/435 264/18722 0.578937292394343 0.776351220790911 GSTP1/SLC2A1/PARP1/GGH/ATP2B1/HADHA 6 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 6/435 264/18722 0.578937292394343 0.776351220790911 CD24/EGFR/APP/EFNA1/MIF/CAV1 6 GO:0006022 aminoglycan metabolic process 3/435 129/18722 0.579593963751653 0.776351220790911 ITIH5/FUCA1/CHPF 3 GO:0070372 regulation of ERK1 and ERK2 cascade 7/435 309/18722 0.58010634794213 0.776351220790911 GSTP1/EGFR/DUSP9/FBLN1/APP/MIF/PHB 7 GO:0001990 regulation of systemic arterial blood pressure by hormone 1/435 37/18722 0.581331480213159 0.776351220790911 MME 1 GO:0002369 T cell cytokine production 1/435 37/18722 0.581331480213159 0.776351220790911 CD55 1 GO:0002724 regulation of T cell cytokine production 1/435 37/18722 0.581331480213159 0.776351220790911 CD55 1 GO:0003016 respiratory system process 1/435 37/18722 0.581331480213159 0.776351220790911 ADH5 1 GO:0003176 aortic valve development 1/435 37/18722 0.581331480213159 0.776351220790911 EFNA1 1 GO:0007340 acrosome reaction 1/435 37/18722 0.581331480213159 0.776351220790911 SPESP1 1 GO:0031646 positive regulation of nervous system process 1/435 37/18722 0.581331480213159 0.776351220790911 DAG1 1 GO:0033120 positive regulation of RNA splicing 1/435 37/18722 0.581331480213159 0.776351220790911 PRDX6 1 GO:0034260 negative regulation of GTPase activity 1/435 37/18722 0.581331480213159 0.776351220790911 AMOT 1 GO:0043368 positive T cell selection 1/435 37/18722 0.581331480213159 0.776351220790911 CTSL 1 GO:0043403 skeletal muscle tissue regeneration 1/435 37/18722 0.581331480213159 0.776351220790911 DAG1 1 GO:0043687 post-translational protein modification 1/435 37/18722 0.581331480213159 0.776351220790911 LCMT1 1 GO:0048846 axon extension involved in axon guidance 1/435 37/18722 0.581331480213159 0.776351220790911 NRP2 1 GO:0051294 establishment of spindle orientation 1/435 37/18722 0.581331480213159 0.776351220790911 GJA1 1 GO:0060416 response to growth hormone 1/435 37/18722 0.581331480213159 0.776351220790911 ASS1 1 GO:1902284 neuron projection extension involved in neuron projection guidance 1/435 37/18722 0.581331480213159 0.776351220790911 NRP2 1 GO:1902745 positive regulation of lamellipodium organization 1/435 37/18722 0.581331480213159 0.776351220790911 WASF2 1 GO:1904358 positive regulation of telomere maintenance via telomere lengthening 1/435 37/18722 0.581331480213159 0.776351220790911 PKIB 1 GO:0048771 tissue remodeling 4/435 175/18722 0.582691873308853 0.777905446249369 EGFR/TGM2/GJA1/CAV1 4 GO:0032508 DNA duplex unwinding 2/435 84/18722 0.584453962393022 0.779199301254076 HMGA1/SSBP1 2 GO:1900542 regulation of purine nucleotide metabolic process 2/435 84/18722 0.584453962393022 0.779199301254076 PARP1/APP 2 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 2/435 84/18722 0.584453962393022 0.779199301254076 CTDSPL/CCND1 2 GO:0006282 regulation of DNA repair 3/435 130/18722 0.5848425384697 0.779199301254076 EGFR/PARP1/RPS3 3 GO:0015918 sterol transport 3/435 130/18722 0.5848425384697 0.779199301254076 ANXA2/CAV1/LPCAT3 3 GO:0030534 adult behavior 3/435 130/18722 0.5848425384697 0.779199301254076 APP/PARK7/ATP6V1B1 3 GO:0018022 peptidyl-lysine methylation 3/435 131/18722 0.590049261789192 0.779892457869499 DNMT1/LMNA/TRMT112 3 GO:0002709 regulation of T cell mediated immunity 2/435 85/18722 0.590912609913436 0.779892457869499 HSPD1/CD55 2 GO:0009142 nucleoside triphosphate biosynthetic process 2/435 85/18722 0.590912609913436 0.779892457869499 PARP1/STOML2 2 GO:0045069 regulation of viral genome replication 2/435 85/18722 0.590912609913436 0.779892457869499 HACD3/DDB1 2 GO:0001825 blastocyst formation 1/435 38/18722 0.591078379121763 0.779892457869499 SF3B6 1 GO:0002385 mucosal immune response 1/435 38/18722 0.591078379121763 0.779892457869499 RAB17 1 GO:0002478 antigen processing and presentation of exogenous peptide antigen 1/435 38/18722 0.591078379121763 0.779892457869499 CTSL 1 GO:0006882 cellular zinc ion homeostasis 1/435 38/18722 0.591078379121763 0.779892457869499 SLC39A10 1 GO:0007094 mitotic spindle assembly checkpoint signaling 1/435 38/18722 0.591078379121763 0.779892457869499 LCMT1 1 GO:0010613 positive regulation of cardiac muscle hypertrophy 1/435 38/18722 0.591078379121763 0.779892457869499 PARP1 1 GO:0010719 negative regulation of epithelial to mesenchymal transition 1/435 38/18722 0.591078379121763 0.779892457869499 EFNA1 1 GO:0035337 fatty-acyl-CoA metabolic process 1/435 38/18722 0.591078379121763 0.779892457869499 TECR 1 GO:0035886 vascular associated smooth muscle cell differentiation 1/435 38/18722 0.591078379121763 0.779892457869499 DNMT1 1 GO:0042491 inner ear auditory receptor cell differentiation 1/435 38/18722 0.591078379121763 0.779892457869499 SOD1 1 GO:0046329 negative regulation of JNK cascade 1/435 38/18722 0.591078379121763 0.779892457869499 GSTP1 1 GO:0046633 alpha-beta T cell proliferation 1/435 38/18722 0.591078379121763 0.779892457869499 CD55 1 GO:0048713 regulation of oligodendrocyte differentiation 1/435 38/18722 0.591078379121763 0.779892457869499 DAG1 1 GO:0051930 regulation of sensory perception of pain 1/435 38/18722 0.591078379121763 0.779892457869499 COMT 1 GO:0071173 spindle assembly checkpoint signaling 1/435 38/18722 0.591078379121763 0.779892457869499 LCMT1 1 GO:0071174 mitotic spindle checkpoint signaling 1/435 38/18722 0.591078379121763 0.779892457869499 LCMT1 1 GO:0071392 cellular response to estradiol stimulus 1/435 38/18722 0.591078379121763 0.779892457869499 EGFR 1 GO:0071398 cellular response to fatty acid 1/435 38/18722 0.591078379121763 0.779892457869499 ASS1 1 GO:0072538 T-helper 17 type immune response 1/435 38/18722 0.591078379121763 0.779892457869499 PHB 1 GO:0098926 postsynaptic signal transduction 1/435 38/18722 0.591078379121763 0.779892457869499 LY6E 1 GO:0099622 cardiac muscle cell membrane repolarization 1/435 38/18722 0.591078379121763 0.779892457869499 GJA5 1 GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 1/435 38/18722 0.591078379121763 0.779892457869499 BNIP3 1 GO:1903580 positive regulation of ATP metabolic process 1/435 38/18722 0.591078379121763 0.779892457869499 APP 1 GO:2000279 negative regulation of DNA biosynthetic process 1/435 38/18722 0.591078379121763 0.779892457869499 GJA1 1 GO:1904062 regulation of cation transmembrane transport 8/435 357/18722 0.591078463773219 0.779892457869499 FXYD3/APP/NDUFA4/PARK7/SLC43A2/KCNN4/TSPAN13/CAV1 8 GO:0030324 lung development 4/435 177/18722 0.591678783564551 0.780160590251682 EGFR/MME/DAG1/LAMA5 4 GO:0051648 vesicle localization 4/435 177/18722 0.591678783564551 0.780160590251682 CLN3/TMED9/PDCD6/RAB17 4 GO:0034765 regulation of ion transmembrane transport 11/435 491/18722 0.591873159447953 0.780160590251682 FXYD3/ARL6IP5/CLIC3/APP/NDUFA4/GJA5/PARK7/SLC43A2/KCNN4/TSPAN13/CAV1 11 GO:0050920 regulation of chemotaxis 5/435 223/18722 0.594260737022294 0.783046865267138 GSTP1/MET/C1QBP/CALR/MIF 5 GO:0045667 regulation of osteoblast differentiation 3/435 132/18722 0.595213844813396 0.784041672412319 FBN2/BMP7/ATRAID 3 GO:0006140 regulation of nucleotide metabolic process 2/435 86/18722 0.597296303675613 0.785344838361511 PARP1/APP 2 GO:0035023 regulation of Rho protein signal transduction 2/435 86/18722 0.597296303675613 0.785344838361511 ADGRG1/MET 2 GO:0060761 negative regulation of response to cytokine stimulus 2/435 86/18722 0.597296303675613 0.785344838361511 GSTP1/CAV1 2 GO:1903510 mucopolysaccharide metabolic process 2/435 86/18722 0.597296303675613 0.785344838361511 ITIH5/CHPF 2 GO:2001251 negative regulation of chromosome organization 2/435 86/18722 0.597296303675613 0.785344838361511 PARP1/LCMT1 2 GO:0051052 regulation of DNA metabolic process 8/435 359/18722 0.597393976110222 0.785344838361511 EGFR/PKIB/ANXA3/PARP1/GJA1/HSP90AB1/RPS3/NPM1 8 GO:0046328 regulation of JNK cascade 3/435 133/18722 0.600336020428516 0.785902691773575 GSTP1/EGFR/APP 3 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 3/435 133/18722 0.600336020428516 0.785902691773575 BCAP31/PSMC1/CAV1 3 GO:0014742 positive regulation of muscle hypertrophy 1/435 39/18722 0.600598872864112 0.785902691773575 PARP1 1 GO:0016233 telomere capping 1/435 39/18722 0.600598872864112 0.785902691773575 PKIB 1 GO:0031507 heterochromatin assembly 1/435 39/18722 0.600598872864112 0.785902691773575 DNMT1 1 GO:0031577 spindle checkpoint signaling 1/435 39/18722 0.600598872864112 0.785902691773575 LCMT1 1 GO:0034314 Arp2/3 complex-mediated actin nucleation 1/435 39/18722 0.600598872864112 0.785902691773575 WASF2 1 GO:0043267 negative regulation of potassium ion transport 1/435 39/18722 0.600598872864112 0.785902691773575 CAV1 1 GO:0045823 positive regulation of heart contraction 1/435 39/18722 0.600598872864112 0.785902691773575 ADRB1 1 GO:0051084 'de novo' posttranslational protein folding 1/435 39/18722 0.600598872864112 0.785902691773575 HSPE1 1 GO:0051931 regulation of sensory perception 1/435 39/18722 0.600598872864112 0.785902691773575 COMT 1 GO:1902742 apoptotic process involved in development 1/435 39/18722 0.600598872864112 0.785902691773575 BMP7 1 GO:2000249 regulation of actin cytoskeleton reorganization 1/435 39/18722 0.600598872864112 0.785902691773575 PHPT1 1 GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 1/435 39/18722 0.600598872864112 0.785902691773575 CD55 1 GO:0044070 regulation of anion transport 2/435 87/18722 0.603605032176774 0.78951729171147 ARL6IP5/SLC43A2 2 GO:0043414 macromolecule methylation 7/435 316/18722 0.603760253909251 0.78951729171147 DNMT1/PARP1/LMNA/SNRPD3/TRMT112/LCMT1/PRMT1 7 GO:0010721 negative regulation of cell development 4/435 180/18722 0.604943546069749 0.790803307498513 FBLN1/BMP7/FBN1/TACSTD2 4 GO:0002705 positive regulation of leukocyte mediated immunity 3/435 134/18722 0.605415542780697 0.790897755953522 HSPD1/CADM1/CD55 3 GO:0032147 activation of protein kinase activity 3/435 134/18722 0.605415542780697 0.790897755953522 RPLP1/PARK7/PHB 3 GO:0002703 regulation of leukocyte mediated immunity 5/435 226/18722 0.60609715773622 0.791008591146888 VAMP8/HSPD1/CD46/CADM1/CD55 5 GO:0006959 humoral immune response 7/435 317/18722 0.607082555550962 0.791008591146888 RPS19/CD59/ROMO1/C1QBP/CD46/CD55/PHB 7 GO:0030323 respiratory tube development 4/435 181/18722 0.609306673492568 0.791008591146888 EGFR/MME/DAG1/LAMA5 4 GO:0009144 purine nucleoside triphosphate metabolic process 2/435 88/18722 0.609838824819711 0.791008591146888 PARP1/STOML2 2 GO:0031110 regulation of microtubule polymerization or depolymerization 2/435 88/18722 0.609838824819711 0.791008591146888 MET/RPS3 2 GO:0050829 defense response to Gram-negative bacterium 2/435 88/18722 0.609838824819711 0.791008591146888 RPS19/ROMO1 2 GO:0009394 2'-deoxyribonucleotide metabolic process 1/435 40/18722 0.60989820864017 0.791008591146888 PNP 1 GO:0030866 cortical actin cytoskeleton organization 1/435 40/18722 0.60989820864017 0.791008591146888 CALR 1 GO:0032094 response to food 1/435 40/18722 0.60989820864017 0.791008591146888 NENF 1 GO:0035329 hippo signaling 1/435 40/18722 0.60989820864017 0.791008591146888 AMOT 1 GO:0044275 cellular carbohydrate catabolic process 1/435 40/18722 0.60989820864017 0.791008591146888 AGL 1 GO:0045022 early endosome to late endosome transport 1/435 40/18722 0.60989820864017 0.791008591146888 SNX3 1 GO:0045841 negative regulation of mitotic metaphase/anaphase transition 1/435 40/18722 0.60989820864017 0.791008591146888 LCMT1 1 GO:0046365 monosaccharide catabolic process 1/435 40/18722 0.60989820864017 0.791008591146888 BAD 1 GO:0055069 zinc ion homeostasis 1/435 40/18722 0.60989820864017 0.791008591146888 SLC39A10 1 GO:0055081 anion homeostasis 1/435 40/18722 0.60989820864017 0.791008591146888 ATP6V1B1 1 GO:0070266 necroptotic process 1/435 40/18722 0.60989820864017 0.791008591146888 CAV1 1 GO:1901223 negative regulation of NIK/NF-kappaB signaling 1/435 40/18722 0.60989820864017 0.791008591146888 BMP7 1 GO:1901661 quinone metabolic process 1/435 40/18722 0.60989820864017 0.791008591146888 AKR1B1 1 GO:1901998 toxin transport 1/435 40/18722 0.60989820864017 0.791008591146888 BNIP3 1 GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 1/435 40/18722 0.60989820864017 0.791008591146888 BNIP3 1 GO:2000781 positive regulation of double-strand break repair 1/435 40/18722 0.60989820864017 0.791008591146888 PARP1 1 GO:0032259 methylation 8/435 364/18722 0.61296930896502 0.79447086654916 COMT/DNMT1/PARP1/LMNA/SNRPD3/TRMT112/LCMT1/PRMT1 8 GO:0050767 regulation of neurogenesis 8/435 364/18722 0.61296930896502 0.79447086654916 SERPINF1/SPINT1/EGFR/BMP7/LRP2/TGM2/MME/DAG1 8 GO:0051260 protein homooligomerization 4/435 182/18722 0.613640203073996 0.794875242739796 MIF/SSBP1/PRMT1/SLC1A5 4 GO:0007204 positive regulation of cytosolic calcium ion concentration 7/435 319/18722 0.613683059532493 0.794875242739796 CD24/TGM2/GJA1/BCAP31/CD55/FIS1/CAV1 7 GO:0009199 ribonucleoside triphosphate metabolic process 2/435 89/18722 0.615997750026681 0.797041927832083 PARP1/STOML2 2 GO:0009416 response to light stimulus 7/435 320/18722 0.616960986776534 0.797041927832083 EGFR/PARP1/MME/APP/NPM1/DDB1/CCND1 7 GO:0045444 fat cell differentiation 5/435 229/18722 0.617734139982227 0.797041927832083 ADIRF/BMP7/ADRB1/BNIP3/CCND1 5 GO:0071356 cellular response to tumor necrosis factor 5/435 229/18722 0.617734139982227 0.797041927832083 KRT18/GSTP1/KRT8/RPS3/ASS1 5 GO:0002366 leukocyte activation involved in immune response 6/435 275/18722 0.618661265207472 0.797041927832083 VAMP8/ANXA3/HSPD1/S100A13/LGALS3/CD46 6 GO:0002251 organ or tissue specific immune response 1/435 41/18722 0.618981512314377 0.797041927832083 RAB17 1 GO:0006418 tRNA aminoacylation for protein translation 1/435 41/18722 0.618981512314377 0.797041927832083 IARS2 1 GO:0007099 centriole replication 1/435 41/18722 0.618981512314377 0.797041927832083 NPM1 1 GO:0009167 purine ribonucleoside monophosphate metabolic process 1/435 41/18722 0.618981512314377 0.797041927832083 PNP 1 GO:0010907 positive regulation of glucose metabolic process 1/435 41/18722 0.618981512314377 0.797041927832083 DDB1 1 GO:0030488 tRNA methylation 1/435 41/18722 0.618981512314377 0.797041927832083 TRMT112 1 GO:0032735 positive regulation of interleukin-12 production 1/435 41/18722 0.618981512314377 0.797041927832083 HSPD1 1 GO:0050892 intestinal absorption 1/435 41/18722 0.618981512314377 0.797041927832083 LPCAT3 1 GO:1900371 regulation of purine nucleotide biosynthetic process 1/435 41/18722 0.618981512314377 0.797041927832083 PARP1 1 GO:1902622 regulation of neutrophil migration 1/435 41/18722 0.618981512314377 0.797041927832083 C1QBP 1 GO:1903524 positive regulation of blood circulation 1/435 41/18722 0.618981512314377 0.797041927832083 ADRB1 1 GO:1905521 regulation of macrophage migration 1/435 41/18722 0.618981512314377 0.797041927832083 MIF 1 GO:2000008 regulation of protein localization to cell surface 1/435 41/18722 0.618981512314377 0.797041927832083 HSP90AB1 1 GO:0030879 mammary gland development 3/435 137/18722 0.620396039774798 0.797824871429599 CDO1/CCND1/CAV1 3 GO:0034754 cellular hormone metabolic process 3/435 137/18722 0.620396039774798 0.797824871429599 COMT/HSD17B1/AKR1B1 3 GO:0055123 digestive system development 3/435 137/18722 0.620396039774798 0.797824871429599 EGFR/WLS/ASS1 3 GO:0060078 regulation of postsynaptic membrane potential 3/435 137/18722 0.620396039774798 0.797824871429599 APP/ADRB1/S1PR2 3 GO:0030901 midbrain development 2/435 90/18722 0.622081913418519 0.798177085407613 UQCRQ/WLS 2 GO:0032392 DNA geometric change 2/435 90/18722 0.622081913418519 0.798177085407613 HMGA1/SSBP1 2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 2/435 90/18722 0.622081913418519 0.798177085407613 BCAP31/CAV1 2 GO:0045638 negative regulation of myeloid cell differentiation 2/435 90/18722 0.622081913418519 0.798177085407613 FBN1/PRMT1 2 GO:0046031 ADP metabolic process 2/435 90/18722 0.622081913418519 0.798177085407613 APP/BAD 2 GO:0046849 bone remodeling 2/435 90/18722 0.622081913418519 0.798177085407613 EGFR/GJA1 2 GO:0099175 regulation of postsynapse organization 2/435 90/18722 0.622081913418519 0.798177085407613 NRP2/EFNA1 2 GO:0043010 camera-type eye development 7/435 322/18722 0.623471531737267 0.798893568504477 EFEMP1/SERPINF1/FBN2/BMP7/FBN1/TENM3/ATP2B1 7 GO:0032273 positive regulation of protein polymerization 3/435 138/18722 0.625302897708394 0.798893568504477 MET/RPS3/WASF2 3 GO:0055076 transition metal ion homeostasis 3/435 138/18722 0.625302897708394 0.798893568504477 SOD1/APP/SLC39A10 3 GO:0006040 amino sugar metabolic process 1/435 42/18722 0.627853791215038 0.798893568504477 EXTL2 1 GO:0010591 regulation of lamellipodium assembly 1/435 42/18722 0.627853791215038 0.798893568504477 WASF2 1 GO:0014003 oligodendrocyte development 1/435 42/18722 0.627853791215038 0.798893568504477 GSTP1 1 GO:0019692 deoxyribose phosphate metabolic process 1/435 42/18722 0.627853791215038 0.798893568504477 PNP 1 GO:0021795 cerebral cortex cell migration 1/435 42/18722 0.627853791215038 0.798893568504477 ADGRG1 1 GO:0030574 collagen catabolic process 1/435 42/18722 0.627853791215038 0.798893568504477 CTSL 1 GO:0030808 regulation of nucleotide biosynthetic process 1/435 42/18722 0.627853791215038 0.798893568504477 PARP1 1 GO:0032689 negative regulation of interferon-gamma production 1/435 42/18722 0.627853791215038 0.798893568504477 C1QBP 1 GO:0032691 negative regulation of interleukin-1 beta production 1/435 42/18722 0.627853791215038 0.798893568504477 GSTP1 1 GO:0033003 regulation of mast cell activation 1/435 42/18722 0.627853791215038 0.798893568504477 VAMP8 1 GO:0035019 somatic stem cell population maintenance 1/435 42/18722 0.627853791215038 0.798893568504477 BMP7 1 GO:0042168 heme metabolic process 1/435 42/18722 0.627853791215038 0.798893568504477 TMEM14C 1 GO:0043507 positive regulation of JUN kinase activity 1/435 42/18722 0.627853791215038 0.798893568504477 RPS3 1 GO:0051452 intracellular pH reduction 1/435 42/18722 0.627853791215038 0.798893568504477 CLN3 1 GO:0071312 cellular response to alkaloid 1/435 42/18722 0.627853791215038 0.798893568504477 TGM2 1 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic 1/435 42/18722 0.627853791215038 0.798893568504477 REXO2 1 GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle 1/435 42/18722 0.627853791215038 0.798893568504477 LCMT1 1 GO:1903432 regulation of TORC1 signaling 1/435 42/18722 0.627853791215038 0.798893568504477 LAMTOR5 1 GO:1904037 positive regulation of epithelial cell apoptotic process 1/435 42/18722 0.627853791215038 0.798893568504477 BAD 1 GO:2000404 regulation of T cell migration 1/435 42/18722 0.627853791215038 0.798893568504477 APP 1 GO:2001222 regulation of neuron migration 1/435 42/18722 0.627853791215038 0.798893568504477 ADGRG1 1 GO:0006354 DNA-templated transcription, elongation 2/435 91/18722 0.628091456056969 0.798893568504477 GTF2H5/POLR2I 2 GO:0006885 regulation of pH 2/435 91/18722 0.628091456056969 0.798893568504477 CLN3/ATP6V1B1 2 GO:0051952 regulation of amine transport 2/435 91/18722 0.628091456056969 0.798893568504477 ARL6IP5/SLC43A2 2 GO:0022898 regulation of transmembrane transporter activity 6/435 278/18722 0.62912176409666 0.799946921764294 FXYD3/APP/NDUFA4/GJA1/PARK7/CAV1 6 GO:1902105 regulation of leukocyte differentiation 6/435 279/18722 0.632571523529833 0.802647989226191 SOD1/PRDX2/PNP/FBN1/BAD/CD46 6 GO:0006497 protein lipidation 2/435 92/18722 0.634026552748291 0.802647989226191 DBI/PYURF 2 GO:0031058 positive regulation of histone modification 2/435 92/18722 0.634026552748291 0.802647989226191 DNMT1/LMNA 2 GO:0035249 synaptic transmission, glutamatergic 2/435 92/18722 0.634026552748291 0.802647989226191 EGFR/CLN3 2 GO:0048525 negative regulation of viral process 2/435 92/18722 0.634026552748291 0.802647989226191 LY6E/SNX3 2 GO:1903312 negative regulation of mRNA metabolic process 2/435 92/18722 0.634026552748291 0.802647989226191 C1QBP/NPM1 2 GO:0002861 regulation of inflammatory response to antigenic stimulus 1/435 43/18722 0.636519936869292 0.802647989226191 PARK7 1 GO:0006284 base-excision repair 1/435 43/18722 0.636519936869292 0.802647989226191 RPS3 1 GO:0006509 membrane protein ectodomain proteolysis 1/435 43/18722 0.636519936869292 0.802647989226191 DAG1 1 GO:0010171 body morphogenesis 1/435 43/18722 0.636519936869292 0.802647989226191 DAG1 1 GO:0016266 O-glycan processing 1/435 43/18722 0.636519936869292 0.802647989226191 GALNT11 1 GO:0021983 pituitary gland development 1/435 43/18722 0.636519936869292 0.802647989226191 CDH1 1 GO:0031952 regulation of protein autophosphorylation 1/435 43/18722 0.636519936869292 0.802647989226191 CAV1 1 GO:0032365 intracellular lipid transport 1/435 43/18722 0.636519936869292 0.802647989226191 ANXA2 1 GO:0033046 negative regulation of sister chromatid segregation 1/435 43/18722 0.636519936869292 0.802647989226191 LCMT1 1 GO:0033048 negative regulation of mitotic sister chromatid segregation 1/435 43/18722 0.636519936869292 0.802647989226191 LCMT1 1 GO:0034661 ncRNA catabolic process 1/435 43/18722 0.636519936869292 0.802647989226191 LIN28B 1 GO:0036230 granulocyte activation 1/435 43/18722 0.636519936869292 0.802647989226191 ANXA3 1 GO:0042181 ketone biosynthetic process 1/435 43/18722 0.636519936869292 0.802647989226191 HSD17B1 1 GO:0045494 photoreceptor cell maintenance 1/435 43/18722 0.636519936869292 0.802647989226191 SLC2A1 1 GO:0045981 positive regulation of nucleotide metabolic process 1/435 43/18722 0.636519936869292 0.802647989226191 APP 1 GO:0060443 mammary gland morphogenesis 1/435 43/18722 0.636519936869292 0.802647989226191 CAV1 1 GO:0098927 vesicle-mediated transport between endosomal compartments 1/435 43/18722 0.636519936869292 0.802647989226191 SNX3 1 GO:1900544 positive regulation of purine nucleotide metabolic process 1/435 43/18722 0.636519936869292 0.802647989226191 APP 1 GO:1901381 positive regulation of potassium ion transmembrane transport 1/435 43/18722 0.636519936869292 0.802647989226191 KCNN4 1 GO:2000816 negative regulation of mitotic sister chromatid separation 1/435 43/18722 0.636519936869292 0.802647989226191 LCMT1 1 GO:0030308 negative regulation of cell growth 4/435 188/18722 0.639009224747659 0.804331157235552 NDUFA13/GJA1/PHB/RBBP7 4 GO:0002831 regulation of response to biotic stimulus 7/435 327/18722 0.639477853612925 0.804331157235552 RPS19/PRDX2/HSPD1/HSP90AB1/C1QBP/CADM1/CD55 7 GO:0034341 response to interferon-gamma 3/435 141/18722 0.639761483776874 0.804331157235552 HSP90AB1/ASS1/CD47 3 GO:0050921 positive regulation of chemotaxis 3/435 141/18722 0.639761483776874 0.804331157235552 MET/C1QBP/CALR 3 GO:1903038 negative regulation of leukocyte cell-cell adhesion 3/435 141/18722 0.639761483776874 0.804331157235552 PRDX2/LGALS3/ASS1 3 GO:0019217 regulation of fatty acid metabolic process 2/435 93/18722 0.639887410406247 0.804331157235552 ACADVL/CAV1 2 GO:0032088 negative regulation of NF-kappaB transcription factor activity 2/435 93/18722 0.639887410406247 0.804331157235552 BMP7/PRDX2 2 GO:0032755 positive regulation of interleukin-6 production 2/435 93/18722 0.639887410406247 0.804331157235552 HSPD1/APP 2 GO:0106027 neuron projection organization 2/435 93/18722 0.639887410406247 0.804331157235552 APP/EFNA1 2 GO:1902807 negative regulation of cell cycle G1/S phase transition 2/435 93/18722 0.639887410406247 0.804331157235552 CTDSPL/CCND1 2 GO:2000045 regulation of G1/S transition of mitotic cell cycle 3/435 142/18722 0.644493311930586 0.805210549143479 EGFR/CTDSPL/CCND1 3 GO:0002066 columnar/cuboidal epithelial cell development 1/435 44/18722 0.644984727675109 0.805210549143479 BAD 1 GO:0006378 mRNA polyadenylation 1/435 44/18722 0.644984727675109 0.805210549143479 APP 1 GO:0006775 fat-soluble vitamin metabolic process 1/435 44/18722 0.644984727675109 0.805210549143479 LRP2 1 GO:0007528 neuromuscular junction development 1/435 44/18722 0.644984727675109 0.805210549143479 APP 1 GO:0008542 visual learning 1/435 44/18722 0.644984727675109 0.805210549143479 APP 1 GO:0009126 purine nucleoside monophosphate metabolic process 1/435 44/18722 0.644984727675109 0.805210549143479 PNP 1 GO:0009262 deoxyribonucleotide metabolic process 1/435 44/18722 0.644984727675109 0.805210549143479 PNP 1 GO:0021517 ventral spinal cord development 1/435 44/18722 0.644984727675109 0.805210549143479 LMO4 1 GO:0032007 negative regulation of TOR signaling 1/435 44/18722 0.644984727675109 0.805210549143479 PDCD6 1 GO:0032620 interleukin-17 production 1/435 44/18722 0.644984727675109 0.805210549143479 PHB 1 GO:0032660 regulation of interleukin-17 production 1/435 44/18722 0.644984727675109 0.805210549143479 PHB 1 GO:0032881 regulation of polysaccharide metabolic process 1/435 44/18722 0.644984727675109 0.805210549143479 PHLDA2 1 GO:0042269 regulation of natural killer cell mediated cytotoxicity 1/435 44/18722 0.644984727675109 0.805210549143479 CADM1 1 GO:0043039 tRNA aminoacylation 1/435 44/18722 0.644984727675109 0.805210549143479 IARS2 1 GO:0044058 regulation of digestive system process 1/435 44/18722 0.644984727675109 0.805210549143479 LPCAT3 1 GO:0045124 regulation of bone resorption 1/435 44/18722 0.644984727675109 0.805210549143479 EGFR 1 GO:0051150 regulation of smooth muscle cell differentiation 1/435 44/18722 0.644984727675109 0.805210549143479 DNMT1 1 GO:0062208 positive regulation of pattern recognition receptor signaling pathway 1/435 44/18722 0.644984727675109 0.805210549143479 CAV1 1 GO:0002690 positive regulation of leukocyte chemotaxis 2/435 94/18722 0.645674266472646 0.805210549143479 C1QBP/CALR 2 GO:0010389 regulation of G2/M transition of mitotic cell cycle 2/435 94/18722 0.645674266472646 0.805210549143479 APP/CCND1 2 GO:0019080 viral gene expression 2/435 94/18722 0.645674266472646 0.805210549143479 EIF3G/SPCS1 2 GO:0030316 osteoclast differentiation 2/435 94/18722 0.645674266472646 0.805210549143479 ANXA2/FBN1 2 GO:0048704 embryonic skeletal system morphogenesis 2/435 94/18722 0.645674266472646 0.805210549143479 BMP7/SLC39A1 2 GO:1903035 negative regulation of response to wounding 2/435 94/18722 0.645674266472646 0.805210549143479 ANXA2/GJA1 2 GO:0018108 peptidyl-tyrosine phosphorylation 8/435 375/18722 0.646099070005772 0.805486458731203 EFEMP1/CD24/EGFR/MET/APP/EFNA1/MIF/CAV1 8 GO:0061564 axon development 10/435 467/18722 0.648089864617469 0.807713887965771 BSG/NRP2/FOLR1/BMP7/APP/HSP90AB1/EFNA1/DAG1/LAMA5/NREP 10 GO:0048638 regulation of developmental growth 7/435 330/18722 0.64889195476864 0.807787954466284 SOD1/DUSP9/PPIB/APP/GJA1/ADRB1/SLC6A4 7 GO:0070371 ERK1 and ERK2 cascade 7/435 330/18722 0.64889195476864 0.807787954466284 GSTP1/EGFR/DUSP9/FBLN1/APP/MIF/PHB 7 GO:0018205 peptidyl-lysine modification 8/435 376/18722 0.649029829411674 0.807787954466284 GCSH/TGM2/DNMT1/PARK7/NDUFAB1/LMNA/CBX4/TRMT112 8 GO:0034763 negative regulation of transmembrane transport 3/435 143/18722 0.649181147107184 0.807787954466284 ARL6IP5/SLC43A2/CAV1 3 GO:0015850 organic hydroxy compound transport 6/435 284/18722 0.649536543191856 0.807787954466284 ANXA2/SLC6A4/PARK7/LY6E/CAV1/LPCAT3 6 GO:1901379 regulation of potassium ion transmembrane transport 2/435 95/18722 0.651387387393658 0.807787954466284 KCNN4/CAV1 2 GO:0051259 protein complex oligomerization 5/435 238/18722 0.651402653157458 0.807787954466284 MIF/SSBP1/STOML2/PRMT1/SLC1A5 5 GO:0003197 endocardial cushion development 1/435 45/18722 0.653252831511779 0.807787954466284 BMP7 1 GO:0006110 regulation of glycolytic process 1/435 45/18722 0.653252831511779 0.807787954466284 APP 1 GO:0010824 regulation of centrosome duplication 1/435 45/18722 0.653252831511779 0.807787954466284 NPM1 1 GO:0035305 negative regulation of dephosphorylation 1/435 45/18722 0.653252831511779 0.807787954466284 LGALS3 1 GO:0035987 endodermal cell differentiation 1/435 45/18722 0.653252831511779 0.807787954466284 ITGB5 1 GO:0042551 neuron maturation 1/435 45/18722 0.653252831511779 0.807787954466284 APP 1 GO:0043038 amino acid activation 1/435 45/18722 0.653252831511779 0.807787954466284 IARS2 1 GO:0043631 RNA polyadenylation 1/435 45/18722 0.653252831511779 0.807787954466284 APP 1 GO:0044088 regulation of vacuole organization 1/435 45/18722 0.653252831511779 0.807787954466284 ANXA2 1 GO:0046189 phenol-containing compound biosynthetic process 1/435 45/18722 0.653252831511779 0.807787954466284 PARK7 1 GO:0051985 negative regulation of chromosome segregation 1/435 45/18722 0.653252831511779 0.807787954466284 LCMT1 1 GO:0060119 inner ear receptor cell development 1/435 45/18722 0.653252831511779 0.807787954466284 SOD1 1 GO:0071354 cellular response to interleukin-6 1/435 45/18722 0.653252831511779 0.807787954466284 PHB 1 GO:0085029 extracellular matrix assembly 1/435 45/18722 0.653252831511779 0.807787954466284 DAG1 1 GO:0098534 centriole assembly 1/435 45/18722 0.653252831511779 0.807787954466284 NPM1 1 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process 1/435 45/18722 0.653252831511779 0.807787954466284 BNIP3 1 GO:1905819 negative regulation of chromosome separation 1/435 45/18722 0.653252831511779 0.807787954466284 LCMT1 1 GO:2000273 positive regulation of signaling receptor activity 1/435 45/18722 0.653252831511779 0.807787954466284 PARK7 1 GO:0007612 learning 3/435 144/18722 0.65382492845561 0.807990394097079 COMT/APP/CLN3 3 GO:0014065 phosphatidylinositol 3-kinase signaling 3/435 144/18722 0.65382492845561 0.807990394097079 EGFR/C1QBP/MYDGF 3 GO:0015914 phospholipid transport 2/435 96/18722 0.657027067150168 0.810681666577242 DBI/KCNN4 2 GO:0030510 regulation of BMP signaling pathway 2/435 96/18722 0.657027067150168 0.810681666577242 LRP2/FBN1 2 GO:0042158 lipoprotein biosynthetic process 2/435 96/18722 0.657027067150168 0.810681666577242 DBI/PYURF 2 GO:0042472 inner ear morphogenesis 2/435 96/18722 0.657027067150168 0.810681666577242 SOD1/ATP6V1B1 2 GO:0042632 cholesterol homeostasis 2/435 96/18722 0.657027067150168 0.810681666577242 CD24/CAV1 2 GO:0050808 synapse organization 9/435 426/18722 0.660650652423012 0.811686753847613 CDH1/NRP2/APP/CLN3/MYH10/EFNA1/DAG1/WASF2/RAB17 9 GO:0019221 cytokine-mediated signaling pathway 10/435 472/18722 0.66114259122806 0.811686753847613 KRT18/CD24/GSTP1/P4HB/KRT8/HSP90AB1/IL10RB/CSF2RA/BAD/CAV1 10 GO:0001974 blood vessel remodeling 1/435 46/18722 0.661328808290297 0.811686753847613 TGM2 1 GO:0006984 ER-nucleus signaling pathway 1/435 46/18722 0.661328808290297 0.811686753847613 LPCAT3 1 GO:0031018 endocrine pancreas development 1/435 46/18722 0.661328808290297 0.811686753847613 BAD 1 GO:0031057 negative regulation of histone modification 1/435 46/18722 0.661328808290297 0.811686753847613 DNMT1 1 GO:0031648 protein destabilization 1/435 46/18722 0.661328808290297 0.811686753847613 SERF2 1 GO:0033047 regulation of mitotic sister chromatid segregation 1/435 46/18722 0.661328808290297 0.811686753847613 LCMT1 1 GO:0035094 response to nicotine 1/435 46/18722 0.661328808290297 0.811686753847613 BAD 1 GO:0043300 regulation of leukocyte degranulation 1/435 46/18722 0.661328808290297 0.811686753847613 VAMP8 1 GO:0043616 keratinocyte proliferation 1/435 46/18722 0.661328808290297 0.811686753847613 FERMT1 1 GO:0048701 embryonic cranial skeleton morphogenesis 1/435 46/18722 0.661328808290297 0.811686753847613 SLC39A1 1 GO:0050919 negative chemotaxis 1/435 46/18722 0.661328808290297 0.811686753847613 NRP2 1 GO:0061028 establishment of endothelial barrier 1/435 46/18722 0.661328808290297 0.811686753847613 S1PR2 1 GO:0061462 protein localization to lysosome 1/435 46/18722 0.661328808290297 0.811686753847613 LAMTOR5 1 GO:0070828 heterochromatin organization 1/435 46/18722 0.661328808290297 0.811686753847613 DNMT1 1 GO:0071827 plasma lipoprotein particle organization 1/435 46/18722 0.661328808290297 0.811686753847613 LPCAT3 1 GO:0010596 negative regulation of endothelial cell migration 2/435 97/18722 0.662593625840498 0.812734958912229 SERPINF1/NR2F2 2 GO:0055092 sterol homeostasis 2/435 97/18722 0.662593625840498 0.812734958912229 CD24/CAV1 2 GO:0032535 regulation of cellular component size 8/435 382/18722 0.66631943611088 0.814093202145598 CLN3/HSP90AB1/DSTN/LAMTOR5/KCNN4/NPM1/KANK4/WASF2 8 GO:1903531 negative regulation of secretion by cell 3/435 147/18722 0.667491576359699 0.814093202145598 VAMP8/GJA1/ERP29 3 GO:0032642 regulation of chemokine production 2/435 98/18722 0.668087408313856 0.814093202145598 GSTP1/APP 2 GO:0001774 microglial cell activation 1/435 47/18722 0.669217112445026 0.814093202145598 APP 1 GO:0006998 nuclear envelope organization 1/435 47/18722 0.669217112445026 0.814093202145598 LMNA 1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 1/435 47/18722 0.669217112445026 0.814093202145598 GSTP1 1 GO:0014911 positive regulation of smooth muscle cell migration 1/435 47/18722 0.669217112445026 0.814093202145598 S100A11 1 GO:0016073 snRNA metabolic process 1/435 47/18722 0.669217112445026 0.814093202145598 NHP2 1 GO:0019884 antigen processing and presentation of exogenous antigen 1/435 47/18722 0.669217112445026 0.814093202145598 CTSL 1 GO:0031641 regulation of myelination 1/435 47/18722 0.669217112445026 0.814093202145598 DAG1 1 GO:0032369 negative regulation of lipid transport 1/435 47/18722 0.669217112445026 0.814093202145598 FIS1 1 GO:0035315 hair cell differentiation 1/435 47/18722 0.669217112445026 0.814093202145598 SOD1 1 GO:0035850 epithelial cell differentiation involved in kidney development 1/435 47/18722 0.669217112445026 0.814093202145598 CD24 1 GO:0045332 phospholipid translocation 1/435 47/18722 0.669217112445026 0.814093202145598 KCNN4 1 GO:0045581 negative regulation of T cell differentiation 1/435 47/18722 0.669217112445026 0.814093202145598 PRDX2 1 GO:0045601 regulation of endothelial cell differentiation 1/435 47/18722 0.669217112445026 0.814093202145598 S1PR2 1 GO:0045646 regulation of erythrocyte differentiation 1/435 47/18722 0.669217112445026 0.814093202145598 PRMT1 1 GO:0045911 positive regulation of DNA recombination 1/435 47/18722 0.669217112445026 0.814093202145598 PARP1 1 GO:0047496 vesicle transport along microtubule 1/435 47/18722 0.669217112445026 0.814093202145598 CLN3 1 GO:0048483 autonomic nervous system development 1/435 47/18722 0.669217112445026 0.814093202145598 NRP2 1 GO:0048512 circadian behavior 1/435 47/18722 0.669217112445026 0.814093202145598 ADRB1 1 GO:0061001 regulation of dendritic spine morphogenesis 1/435 47/18722 0.669217112445026 0.814093202145598 EFNA1 1 GO:0072583 clathrin-dependent endocytosis 1/435 47/18722 0.669217112445026 0.814093202145598 CLTA 1 GO:0090279 regulation of calcium ion import 1/435 47/18722 0.669217112445026 0.814093202145598 LGALS3 1 GO:0097300 programmed necrotic cell death 1/435 47/18722 0.669217112445026 0.814093202145598 CAV1 1 GO:1900744 regulation of p38MAPK cascade 1/435 47/18722 0.669217112445026 0.814093202145598 PRMT1 1 GO:0071375 cellular response to peptide hormone stimulus 6/435 290/18722 0.669255796456818 0.814093202145598 GSTP1/PARP1/FBN1/ASS1/ATP2B1/CAV1 6 GO:0007265 Ras protein signal transduction 7/435 337/18722 0.670287739675286 0.815097905929658 ADGRG1/MET/DNMT1/HACD3/PARK7/CTNNAL1/WASF2 7 GO:0010212 response to ionizing radiation 3/435 148/18722 0.671958844529796 0.816879000861568 PARP1/GTF2H5/CCND1 3 GO:0018209 peptidyl-serine modification 7/435 338/18722 0.673277845022266 0.8177582859003 EGFR/PARP1/APP/HSP90AB1/PARK7/MIF/CAV1 7 GO:0003300 cardiac muscle hypertrophy 2/435 99/18722 0.673508782852939 0.8177582859003 PARP1/LMNA 2 GO:0015837 amine transport 2/435 99/18722 0.673508782852939 0.8177582859003 ARL6IP5/SLC43A2 2 GO:0032602 chemokine production 2/435 99/18722 0.673508782852939 0.8177582859003 GSTP1/APP 2 GO:0006814 sodium ion transport 5/435 245/18722 0.67625418936566 0.819639146686398 FXYD3/SLC6A4/SLC13A3/MAGED2/ATP6V1B1 5 GO:0002686 negative regulation of leukocyte migration 1/435 48/18722 0.676922095367993 0.819639146686398 MIF 1 GO:0002715 regulation of natural killer cell mediated immunity 1/435 48/18722 0.676922095367993 0.819639146686398 CADM1 1 GO:0006111 regulation of gluconeogenesis 1/435 48/18722 0.676922095367993 0.819639146686398 DDB1 1 GO:0010569 regulation of double-strand break repair via homologous recombination 1/435 48/18722 0.676922095367993 0.819639146686398 PARP1 1 GO:0042149 cellular response to glucose starvation 1/435 48/18722 0.676922095367993 0.819639146686398 SLC2A1 1 GO:0090311 regulation of protein deacetylation 1/435 48/18722 0.676922095367993 0.819639146686398 BEX4 1 GO:1902003 regulation of amyloid-beta formation 1/435 48/18722 0.676922095367993 0.819639146686398 EFNA1 1 GO:1903053 regulation of extracellular matrix organization 1/435 48/18722 0.676922095367993 0.819639146686398 DAG1 1 GO:0048167 regulation of synaptic plasticity 4/435 198/18722 0.678818562220368 0.820476988271439 MME/APP/CLN3/NSG1 4 GO:0006664 glycolipid metabolic process 2/435 100/18722 0.678858139904142 0.820476988271439 FUCA1/PYURF 2 GO:0044728 DNA methylation or demethylation 2/435 100/18722 0.678858139904142 0.820476988271439 DNMT1/PARP1 2 GO:0045807 positive regulation of endocytosis 2/435 100/18722 0.678858139904142 0.820476988271439 ANXA2/CLN3 2 GO:0060079 excitatory postsynaptic potential 2/435 100/18722 0.678858139904142 0.820476988271439 APP/S1PR2 2 GO:0061640 cytoskeleton-dependent cytokinesis 2/435 100/18722 0.678858139904142 0.820476988271439 MYH10/RHOC 2 GO:0010948 negative regulation of cell cycle process 6/435 294/18722 0.682005692550888 0.820715383882929 BMP7/AURKAIP1/CTDSPL/NPM1/CCND1/LCMT1 6 GO:0051963 regulation of synapse assembly 2/435 101/18722 0.684135890853889 0.820715383882929 APP/RAB17 2 GO:1903509 liposaccharide metabolic process 2/435 101/18722 0.684135890853889 0.820715383882929 FUCA1/PYURF 2 GO:0002204 somatic recombination of immunoglobulin genes involved in immune response 1/435 49/18722 0.684448007787128 0.820715383882929 HSPD1 1 GO:0002208 somatic diversification of immunoglobulins involved in immune response 1/435 49/18722 0.684448007787128 0.820715383882929 HSPD1 1 GO:0002762 negative regulation of myeloid leukocyte differentiation 1/435 49/18722 0.684448007787128 0.820715383882929 FBN1 1 GO:0006778 porphyrin-containing compound metabolic process 1/435 49/18722 0.684448007787128 0.820715383882929 TMEM14C 1 GO:0006953 acute-phase response 1/435 49/18722 0.684448007787128 0.820715383882929 ASS1 1 GO:0007622 rhythmic behavior 1/435 49/18722 0.684448007787128 0.820715383882929 ADRB1 1 GO:0008206 bile acid metabolic process 1/435 49/18722 0.684448007787128 0.820715383882929 SLC27A2 1 GO:0009994 oocyte differentiation 1/435 49/18722 0.684448007787128 0.820715383882929 LGR5 1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 1/435 49/18722 0.684448007787128 0.820715383882929 BMP7 1 GO:0021515 cell differentiation in spinal cord 1/435 49/18722 0.684448007787128 0.820715383882929 LMO4 1 GO:0021695 cerebellar cortex development 1/435 49/18722 0.684448007787128 0.820715383882929 UQCRQ 1 GO:0030195 negative regulation of blood coagulation 1/435 49/18722 0.684448007787128 0.820715383882929 ANXA2 1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 1/435 49/18722 0.684448007787128 0.820715383882929 SKP2 1 GO:0032692 negative regulation of interleukin-1 production 1/435 49/18722 0.684448007787128 0.820715383882929 GSTP1 1 GO:0038084 vascular endothelial growth factor signaling pathway 1/435 49/18722 0.684448007787128 0.820715383882929 NRP2 1 GO:0042304 regulation of fatty acid biosynthetic process 1/435 49/18722 0.684448007787128 0.820715383882929 ACADVL 1 GO:0045190 isotype switching 1/435 49/18722 0.684448007787128 0.820715383882929 HSPD1 1 GO:0046580 negative regulation of Ras protein signal transduction 1/435 49/18722 0.684448007787128 0.820715383882929 MET 1 GO:0046605 regulation of centrosome cycle 1/435 49/18722 0.684448007787128 0.820715383882929 NPM1 1 GO:0051445 regulation of meiotic cell cycle 1/435 49/18722 0.684448007787128 0.820715383882929 CALR 1 GO:0051932 synaptic transmission, GABAergic 1/435 49/18722 0.684448007787128 0.820715383882929 CLN3 1 GO:0060986 endocrine hormone secretion 1/435 49/18722 0.684448007787128 0.820715383882929 GJA1 1 GO:0070741 response to interleukin-6 1/435 49/18722 0.684448007787128 0.820715383882929 PHB 1 GO:0006261 DNA-dependent DNA replication 3/435 151/18722 0.685095999168361 0.820994811844096 HMGA1/SSBP1/STOML2 3 GO:0055067 monovalent inorganic cation homeostasis 3/435 151/18722 0.685095999168361 0.820994811844096 COMT/CLN3/ATP6V1B1 3 GO:0051656 establishment of organelle localization 8/435 390/18722 0.688565306585543 0.821809862284325 VAMP8/GJA1/CLN3/S100A13/TMED9/NPM1/PDCD6/RAB17 8 GO:0006672 ceramide metabolic process 2/435 102/18722 0.689342466849632 0.821809862284325 DEGS1/ORMDL1 2 GO:0014897 striated muscle hypertrophy 2/435 102/18722 0.689342466849632 0.821809862284325 PARP1/LMNA 2 GO:0032677 regulation of interleukin-8 production 2/435 102/18722 0.689342466849632 0.821809862284325 PARK7/LAMTOR5 2 GO:1902106 negative regulation of leukocyte differentiation 2/435 102/18722 0.689342466849632 0.821809862284325 PRDX2/FBN1 2 GO:1904063 negative regulation of cation transmembrane transport 2/435 102/18722 0.689342466849632 0.821809862284325 SLC43A2/CAV1 2 GO:0030509 BMP signaling pathway 3/435 152/18722 0.68938697021653 0.821809862284325 BMP7/LRP2/FBN1 3 GO:0031056 regulation of histone modification 3/435 152/18722 0.68938697021653 0.821809862284325 DNMT1/PARK7/LMNA 3 GO:0050871 positive regulation of B cell activation 3/435 152/18722 0.68938697021653 0.821809862284325 SLC39A10/BAD/MIF 3 GO:0002639 positive regulation of immunoglobulin production 1/435 50/18722 0.691799002089736 0.821809862284325 PHB 1 GO:0007632 visual behavior 1/435 50/18722 0.691799002089736 0.821809862284325 APP 1 GO:0008089 anterograde axonal transport 1/435 50/18722 0.691799002089736 0.821809862284325 SOD1 1 GO:0010665 regulation of cardiac muscle cell apoptotic process 1/435 50/18722 0.691799002089736 0.821809862284325 BNIP3 1 GO:0015872 dopamine transport 1/435 50/18722 0.691799002089736 0.821809862284325 PARK7 1 GO:0018023 peptidyl-lysine trimethylation 1/435 50/18722 0.691799002089736 0.821809862284325 LMNA 1 GO:0038093 Fc receptor signaling pathway 1/435 50/18722 0.691799002089736 0.821809862284325 CD47 1 GO:0038202 TORC1 signaling 1/435 50/18722 0.691799002089736 0.821809862284325 LAMTOR5 1 GO:0042572 retinol metabolic process 1/435 50/18722 0.691799002089736 0.821809862284325 AKR1B1 1 GO:0043268 positive regulation of potassium ion transport 1/435 50/18722 0.691799002089736 0.821809862284325 KCNN4 1 GO:0043628 ncRNA 3'-end processing 1/435 50/18722 0.691799002089736 0.821809862284325 RPS21 1 GO:0045058 T cell selection 1/435 50/18722 0.691799002089736 0.821809862284325 CTSL 1 GO:0045814 negative regulation of gene expression, epigenetic 1/435 50/18722 0.691799002089736 0.821809862284325 DNMT1 1 GO:0046638 positive regulation of alpha-beta T cell differentiation 1/435 50/18722 0.691799002089736 0.821809862284325 PNP 1 GO:0060337 type I interferon signaling pathway 1/435 50/18722 0.691799002089736 0.821809862284325 HSP90AB1 1 GO:0060425 lung morphogenesis 1/435 50/18722 0.691799002089736 0.821809862284325 DAG1 1 GO:0071825 protein-lipid complex subunit organization 1/435 50/18722 0.691799002089736 0.821809862284325 LPCAT3 1 GO:0099054 presynapse assembly 1/435 50/18722 0.691799002089736 0.821809862284325 APP 1 GO:1900047 negative regulation of hemostasis 1/435 50/18722 0.691799002089736 0.821809862284325 ANXA2 1 GO:1901570 fatty acid derivative biosynthetic process 1/435 50/18722 0.691799002089736 0.821809862284325 TECR 1 GO:0120254 olefinic compound metabolic process 3/435 153/18722 0.693634000981741 0.82326264319859 GSTP1/HSD17B1/AKR1B1 3 GO:0019722 calcium-mediated signaling 4/435 202/18722 0.693860153907492 0.82326264319859 EGFR/BCAP31/NUDT4/FIS1 4 GO:0009135 purine nucleoside diphosphate metabolic process 2/435 103/18722 0.694478317664112 0.82326264319859 APP/BAD 2 GO:0009179 purine ribonucleoside diphosphate metabolic process 2/435 103/18722 0.694478317664112 0.82326264319859 APP/BAD 2 GO:0019233 sensory perception of pain 2/435 103/18722 0.694478317664112 0.82326264319859 COMT/MME 2 GO:0032637 interleukin-8 production 2/435 103/18722 0.694478317664112 0.82326264319859 PARK7/LAMTOR5 2 GO:0050773 regulation of dendrite development 2/435 103/18722 0.694478317664112 0.82326264319859 BMP7/RAB17 2 GO:0002443 leukocyte mediated immunity 9/435 440/18722 0.697402313560497 0.823347785321294 PRDX1/VAMP8/ANXA3/HSPD1/S100A13/C1QBP/CD46/CADM1/CD55 9 GO:0051090 regulation of DNA-binding transcription factor activity 9/435 440/18722 0.697402313560497 0.823347785321294 BMP7/ANXA3/PRDX2/APP/RPS3/PARK7/LAMTOR5/NPM1/CAV1 9 GO:1901990 regulation of mitotic cell cycle phase transition 6/435 299/18722 0.697489408450334 0.823347785321294 EGFR/APP/CTDSPL/DDB1/CCND1/LCMT1 6 GO:0008360 regulation of cell shape 3/435 154/18722 0.697837169739205 0.823347785321294 MYH10/DAG1/RHOC 3 GO:0016052 carbohydrate catabolic process 3/435 154/18722 0.697837169739205 0.823347785321294 APP/AGL/BAD 3 GO:0051168 nuclear export 3/435 154/18722 0.697837169739205 0.823347785321294 PARK7/CALR/NPM1 3 GO:0009948 anterior/posterior axis specification 1/435 51/18722 0.698979134592466 0.823347785321294 WLS 1 GO:0010874 regulation of cholesterol efflux 1/435 51/18722 0.698979134592466 0.823347785321294 CAV1 1 GO:0014009 glial cell proliferation 1/435 51/18722 0.698979134592466 0.823347785321294 EGFR 1 GO:0032873 negative regulation of stress-activated MAPK cascade 1/435 51/18722 0.698979134592466 0.823347785321294 GSTP1 1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 1/435 51/18722 0.698979134592466 0.823347785321294 GSTP1 1 GO:0045661 regulation of myoblast differentiation 1/435 51/18722 0.698979134592466 0.823347785321294 MBNL3 1 GO:0046850 regulation of bone remodeling 1/435 51/18722 0.698979134592466 0.823347785321294 EGFR 1 GO:0048013 ephrin receptor signaling pathway 1/435 51/18722 0.698979134592466 0.823347785321294 EFNA1 1 GO:0051293 establishment of spindle localization 1/435 51/18722 0.698979134592466 0.823347785321294 GJA1 1 GO:0060043 regulation of cardiac muscle cell proliferation 1/435 51/18722 0.698979134592466 0.823347785321294 GJA1 1 GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 1/435 51/18722 0.698979134592466 0.823347785321294 GSTP1 1 GO:0071622 regulation of granulocyte chemotaxis 1/435 51/18722 0.698979134592466 0.823347785321294 C1QBP 1 GO:1903307 positive regulation of regulated secretory pathway 1/435 51/18722 0.698979134592466 0.823347785321294 VAMP8 1 GO:0014896 muscle hypertrophy 2/435 104/18722 0.699543910601514 0.823347785321294 PARP1/LMNA 2 GO:0022600 digestive system process 2/435 104/18722 0.699543910601514 0.823347785321294 KCNN4/LPCAT3 2 GO:0046634 regulation of alpha-beta T cell activation 2/435 104/18722 0.699543910601514 0.823347785321294 PNP/CD55 2 GO:0060419 heart growth 2/435 104/18722 0.699543910601514 0.823347785321294 DUSP9/GJA1 2 GO:1901890 positive regulation of cell junction assembly 2/435 104/18722 0.699543910601514 0.823347785321294 S100A10/CAV1 2 GO:0045017 glycerolipid biosynthetic process 5/435 252/18722 0.699903809879059 0.823526427502657 TMEM150A/CLN3/PISD/PYURF/LPCAT3 5 GO:0010970 transport along microtubule 3/435 155/18722 0.701996566409958 0.825743285756304 SOD1/APP/CLN3 3 GO:0043087 regulation of GTPase activity 7/435 348/18722 0.702243106007053 0.825787806974713 ITGA6/SOD1/TGM2/MET/ADRB1/S100A10/AMOT 7 GO:0034612 response to tumor necrosis factor 5/435 253/18722 0.70318312811939 0.826647545445165 KRT18/GSTP1/KRT8/RPS3/ASS1 5 GO:0000041 transition metal ion transport 2/435 105/18722 0.704539729444189 0.826897407559042 SLC39A1/SLC39A10 2 GO:0062207 regulation of pattern recognition receptor signaling pathway 2/435 105/18722 0.704539729444189 0.826897407559042 C1QBP/CAV1 2 GO:0010718 positive regulation of epithelial to mesenchymal transition 1/435 52/18722 0.705992367758995 0.826897407559042 BMP7 1 GO:0021545 cranial nerve development 1/435 52/18722 0.705992367758995 0.826897407559042 NRP2 1 GO:0032206 positive regulation of telomere maintenance 1/435 52/18722 0.705992367758995 0.826897407559042 PKIB 1 GO:0034204 lipid translocation 1/435 52/18722 0.705992367758995 0.826897407559042 KCNN4 1 GO:0035176 social behavior 1/435 52/18722 0.705992367758995 0.826897407559042 SLC6A4 1 GO:0043277 apoptotic cell clearance 1/435 52/18722 0.705992367758995 0.826897407559042 TGM2 1 GO:0045010 actin nucleation 1/435 52/18722 0.705992367758995 0.826897407559042 WASF2 1 GO:0048260 positive regulation of receptor-mediated endocytosis 1/435 52/18722 0.705992367758995 0.826897407559042 ANXA2 1 GO:0071357 cellular response to type I interferon 1/435 52/18722 0.705992367758995 0.826897407559042 HSP90AB1 1 GO:0072132 mesenchyme morphogenesis 1/435 52/18722 0.705992367758995 0.826897407559042 BMP7 1 GO:0001764 neuron migration 3/435 156/18722 0.706112292176397 0.826897407559042 ADGRG1/NRP2/NR2F2 3 GO:0006090 pyruvate metabolic process 2/435 106/18722 0.709466273438664 0.829587160392877 APP/MPC2 2 GO:0009185 ribonucleoside diphosphate metabolic process 2/435 106/18722 0.709466273438664 0.829587160392877 APP/BAD 2 GO:0019882 antigen processing and presentation 2/435 106/18722 0.709466273438664 0.829587160392877 CTSL/CALR 2 GO:0099565 chemical synaptic transmission, postsynaptic 2/435 106/18722 0.709466273438664 0.829587160392877 APP/S1PR2 2 GO:1903707 negative regulation of hemopoiesis 2/435 106/18722 0.709466273438664 0.829587160392877 PRDX2/FBN1 2 GO:0051924 regulation of calcium ion transport 5/435 255/18722 0.70966705532724 0.829587160392877 GJA1/LGALS3/ATP2B1/TSPAN13/CAV1 5 GO:1902107 positive regulation of leukocyte differentiation 3/435 157/18722 0.710184459104766 0.829701772860218 PNP/BAD/CD46 3 GO:1903708 positive regulation of hemopoiesis 3/435 157/18722 0.710184459104766 0.829701772860218 PNP/BAD/CD46 3 GO:0016064 immunoglobulin mediated immune response 4/435 207/18722 0.711948309953515 0.83060013511626 HSPD1/C1QBP/CD46/CD55 4 GO:0001541 ovarian follicle development 1/435 53/18722 0.712842572366646 0.83060013511626 SOD1 1 GO:0008347 glial cell migration 1/435 53/18722 0.712842572366646 0.83060013511626 ADGRG1 1 GO:0031279 regulation of cyclase activity 1/435 53/18722 0.712842572366646 0.83060013511626 GNAS 1 GO:0032210 regulation of telomere maintenance via telomerase 1/435 53/18722 0.712842572366646 0.83060013511626 PKIB 1 GO:0033059 cellular pigmentation 1/435 53/18722 0.712842572366646 0.83060013511626 RAB17 1 GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 1/435 53/18722 0.712842572366646 0.83060013511626 MET 1 GO:0099172 presynapse organization 1/435 53/18722 0.712842572366646 0.83060013511626 APP 1 GO:1990090 cellular response to nerve growth factor stimulus 1/435 53/18722 0.712842572366646 0.83060013511626 APP 1 GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 2/435 107/18722 0.71432405631968 0.83159173017269 HSPD1/CD55 2 GO:0031532 actin cytoskeleton reorganization 2/435 107/18722 0.71432405631968 0.83159173017269 PHPT1/S1PR2 2 GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 2/435 107/18722 0.71432405631968 0.83159173017269 BCAP31/CAV1 2 GO:0002573 myeloid leukocyte differentiation 4/435 208/18722 0.71547080939057 0.832681762576025 ANXA2/PARP1/APP/FBN1 4 GO:0071222 cellular response to lipopolysaccharide 4/435 209/18722 0.718961654900392 0.83446488180497 GSTP1/PRDX2/ASS1/CD55 4 GO:0001706 endoderm formation 1/435 54/18722 0.719533529623087 0.83446488180497 ITGB5 1 GO:0010524 positive regulation of calcium ion transport into cytosol 1/435 54/18722 0.719533529623087 0.83446488180497 CAV1 1 GO:0010659 cardiac muscle cell apoptotic process 1/435 54/18722 0.719533529623087 0.83446488180497 BNIP3 1 GO:0014888 striated muscle adaptation 1/435 54/18722 0.719533529623087 0.83446488180497 LMNA 1 GO:0030834 regulation of actin filament depolymerization 1/435 54/18722 0.719533529623087 0.83446488180497 DSTN 1 GO:0032330 regulation of chondrocyte differentiation 1/435 54/18722 0.719533529623087 0.83446488180497 EFEMP1 1 GO:0035065 regulation of histone acetylation 1/435 54/18722 0.719533529623087 0.83446488180497 PARK7 1 GO:0043647 inositol phosphate metabolic process 1/435 54/18722 0.719533529623087 0.83446488180497 NUDT4 1 GO:0051703 biological process involved in intraspecies interaction between organisms 1/435 54/18722 0.719533529623087 0.83446488180497 SLC6A4 1 GO:0070839 metal ion export 1/435 54/18722 0.719533529623087 0.83446488180497 ATP2B1 1 GO:1902743 regulation of lamellipodium organization 1/435 54/18722 0.719533529623087 0.83446488180497 WASF2 1 GO:0043271 negative regulation of ion transport 3/435 160/18722 0.722140883048055 0.837243326756858 ARL6IP5/SLC43A2/CAV1 3 GO:0019724 B cell mediated immunity 4/435 210/18722 0.722420884263306 0.837322624203252 HSPD1/C1QBP/CD46/CD55 4 GO:0043266 regulation of potassium ion transport 2/435 109/18722 0.723835460522131 0.83871652043516 KCNN4/CAV1 2 GO:0002067 glandular epithelial cell differentiation 1/435 55/18722 0.726068933234292 0.840074493803535 BAD 1 GO:0010676 positive regulation of cellular carbohydrate metabolic process 1/435 55/18722 0.726068933234292 0.840074493803535 DDB1 1 GO:0038066 p38MAPK cascade 1/435 55/18722 0.726068933234292 0.840074493803535 PRMT1 1 GO:0045620 negative regulation of lymphocyte differentiation 1/435 55/18722 0.726068933234292 0.840074493803535 PRDX2 1 GO:1902991 regulation of amyloid precursor protein catabolic process 1/435 55/18722 0.726068933234292 0.840074493803535 EFNA1 1 GO:0032611 interleukin-1 beta production 2/435 110/18722 0.728490173478874 0.842137194407217 GSTP1/APP 2 GO:0032651 regulation of interleukin-1 beta production 2/435 110/18722 0.728490173478874 0.842137194407217 GSTP1/APP 2 GO:0048259 regulation of receptor-mediated endocytosis 2/435 110/18722 0.728490173478874 0.842137194407217 ANXA2/LRPAP1 2 GO:0032409 regulation of transporter activity 6/435 310/18722 0.729753638779812 0.843270261428233 FXYD3/APP/NDUFA4/GJA1/PARK7/CAV1 6 GO:0034250 positive regulation of cellular amide metabolic process 3/435 162/18722 0.729896549252388 0.843270261428233 EFNA1/C1QBP/NPM1 3 GO:0001912 positive regulation of leukocyte mediated cytotoxicity 1/435 56/18722 0.732452391424846 0.843940376717921 CADM1 1 GO:0002090 regulation of receptor internalization 1/435 56/18722 0.732452391424846 0.843940376717921 LRPAP1 1 GO:0002886 regulation of myeloid leukocyte mediated immunity 1/435 56/18722 0.732452391424846 0.843940376717921 VAMP8 1 GO:0022029 telencephalon cell migration 1/435 56/18722 0.732452391424846 0.843940376717921 ADGRG1 1 GO:0043470 regulation of carbohydrate catabolic process 1/435 56/18722 0.732452391424846 0.843940376717921 APP 1 GO:0051058 negative regulation of small GTPase mediated signal transduction 1/435 56/18722 0.732452391424846 0.843940376717921 MET 1 GO:0051653 spindle localization 1/435 56/18722 0.732452391424846 0.843940376717921 GJA1 1 GO:0098781 ncRNA transcription 1/435 56/18722 0.732452391424846 0.843940376717921 POLR2L 1 GO:1990089 response to nerve growth factor 1/435 56/18722 0.732452391424846 0.843940376717921 APP 1 GO:0001505 regulation of neurotransmitter levels 4/435 213/18722 0.732609349008354 0.843940376717921 COMT/CLN3/SLC6A4/PARK7 4 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 2/435 111/18722 0.733078306888151 0.844234825482076 EGFR/MYDGF 2 GO:0000082 G1/S transition of mitotic cell cycle 4/435 214/18722 0.73594261809331 0.847286860574695 EGFR/CTDSPL/SKP2/CCND1 4 GO:0009314 response to radiation 9/435 456/18722 0.736226542182611 0.847367198201452 ADIRF/EGFR/PARP1/MME/APP/GTF2H5/NPM1/DDB1/CCND1 9 GO:0001676 long-chain fatty acid metabolic process 2/435 112/18722 0.737600433534483 0.847488012816387 GSTP1/SLC27A2 2 GO:0002821 positive regulation of adaptive immune response 2/435 112/18722 0.737600433534483 0.847488012816387 HSPD1/CD55 2 GO:0046632 alpha-beta T cell differentiation 2/435 112/18722 0.737600433534483 0.847488012816387 CTSL/PNP 2 GO:0045787 positive regulation of cell cycle 6/435 313/18722 0.738120451688442 0.847488012816387 EGFR/APP/SLC6A4/CALR/NPM1/CCND1 6 GO:0007346 regulation of mitotic cell cycle 9/435 457/18722 0.73853767402894 0.847488012816387 EGFR/CDKN1C/BMP7/AURKAIP1/APP/CTDSPL/DDB1/CCND1/LCMT1 9 GO:0006949 syncytium formation 1/435 57/18722 0.738687428911731 0.847488012816387 ERVH48-1 1 GO:0016447 somatic recombination of immunoglobulin gene segments 1/435 57/18722 0.738687428911731 0.847488012816387 HSPD1 1 GO:0033619 membrane protein proteolysis 1/435 57/18722 0.738687428911731 0.847488012816387 DAG1 1 GO:0034205 amyloid-beta formation 1/435 57/18722 0.738687428911731 0.847488012816387 EFNA1 1 GO:0051289 protein homotetramerization 1/435 57/18722 0.738687428911731 0.847488012816387 SSBP1 1 GO:0061005 cell differentiation involved in kidney development 1/435 57/18722 0.738687428911731 0.847488012816387 CD24 1 GO:0032635 interleukin-6 production 3/435 165/18722 0.741210428868544 0.849889790505022 HSPD1/APP/CD47 3 GO:0032675 regulation of interleukin-6 production 3/435 165/18722 0.741210428868544 0.849889790505022 HSPD1/APP/CD47 3 GO:0031623 receptor internalization 2/435 113/18722 0.742057135567993 0.850614161483936 LRPAP1/CAV1 2 GO:0018105 peptidyl-serine phosphorylation 6/435 315/18722 0.743595225180173 0.851266471204702 EGFR/APP/HSP90AB1/PARK7/MIF/CAV1 6 GO:0009161 ribonucleoside monophosphate metabolic process 1/435 58/18722 0.74477748883262 0.851266471204702 PNP 1 GO:0010559 regulation of glycoprotein biosynthetic process 1/435 58/18722 0.74477748883262 0.851266471204702 TMEM59 1 GO:0032481 positive regulation of type I interferon production 1/435 58/18722 0.74477748883262 0.851266471204702 HSPD1 1 GO:0034340 response to type I interferon 1/435 58/18722 0.74477748883262 0.851266471204702 HSP90AB1 1 GO:0043525 positive regulation of neuron apoptotic process 1/435 58/18722 0.74477748883262 0.851266471204702 FIS1 1 GO:0050432 catecholamine secretion 1/435 58/18722 0.74477748883262 0.851266471204702 LY6E 1 GO:0097035 regulation of membrane lipid distribution 1/435 58/18722 0.74477748883262 0.851266471204702 KCNN4 1 GO:2000649 regulation of sodium ion transmembrane transporter activity 1/435 58/18722 0.74477748883262 0.851266471204702 FXYD3 1 GO:2000736 regulation of stem cell differentiation 1/435 58/18722 0.74477748883262 0.851266471204702 TACSTD2 1 GO:0008154 actin polymerization or depolymerization 4/435 217/18722 0.745754724320612 0.851891294496727 DSTN/MSRB2/KANK4/WASF2 4 GO:0070374 positive regulation of ERK1 and ERK2 cascade 4/435 217/18722 0.745754724320612 0.851891294496727 EGFR/APP/MIF/PHB 4 GO:0002286 T cell activation involved in immune response 2/435 114/18722 0.746449003762627 0.852438299534982 LGALS3/CD46 2 GO:0034728 nucleosome organization 3/435 167/18722 0.748542107649543 0.854335483117751 HMGA1/ZNHIT1/NPM1 3 GO:0055088 lipid homeostasis 3/435 167/18722 0.748542107649543 0.854335483117751 CD24/CAV1/ORMDL1 3 GO:0021885 forebrain cell migration 1/435 59/18722 0.75072593462976 0.854667189825088 ADGRG1 1 GO:0030042 actin filament depolymerization 1/435 59/18722 0.75072593462976 0.854667189825088 DSTN 1 GO:0033013 tetrapyrrole metabolic process 1/435 59/18722 0.75072593462976 0.854667189825088 TMEM14C 1 GO:0048010 vascular endothelial growth factor receptor signaling pathway 1/435 59/18722 0.75072593462976 0.854667189825088 PDCD6 1 GO:0048278 vesicle docking 1/435 59/18722 0.75072593462976 0.854667189825088 CLN3 1 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 1/435 59/18722 0.75072593462976 0.854667189825088 CAV1 1 GO:0051568 histone H3-K4 methylation 1/435 59/18722 0.75072593462976 0.854667189825088 DNMT1 1 GO:2001258 negative regulation of cation channel activity 1/435 59/18722 0.75072593462976 0.854667189825088 CAV1 1 GO:0042471 ear morphogenesis 2/435 115/18722 0.75077663680364 0.854667189825088 SOD1/ATP6V1B1 2 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3/435 168/18722 0.752145279358009 0.855241054718288 HSPD1/CD46/CD55 3 GO:0002833 positive regulation of response to biotic stimulus 3/435 168/18722 0.752145279358009 0.855241054718288 RPS19/HSPD1/CADM1 3 GO:0099173 postsynapse organization 3/435 168/18722 0.752145279358009 0.855241054718288 NRP2/EFNA1/WASF2 3 GO:1902806 regulation of cell cycle G1/S phase transition 3/435 168/18722 0.752145279358009 0.855241054718288 EGFR/CTDSPL/CCND1 3 GO:1903706 regulation of hemopoiesis 7/435 367/18722 0.752479432366081 0.855375212258714 SOD1/PRDX2/PNP/FBN1/BAD/CD46/PRMT1 7 GO:0030326 embryonic limb morphogenesis 2/435 116/18722 0.755040640603403 0.857793802718251 FBN2/BMP7 2 GO:0035113 embryonic appendage morphogenesis 2/435 116/18722 0.755040640603403 0.857793802718251 FBN2/BMP7 2 GO:0048705 skeletal system morphogenesis 4/435 220/18722 0.755287003667825 0.857827403419513 FBN2/BMP7/SLC39A1/MSX2 4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 1/435 60/18722 0.756536051890439 0.858506784436612 MBNL3 1 GO:0030071 regulation of mitotic metaphase/anaphase transition 1/435 60/18722 0.756536051890439 0.858506784436612 LCMT1 1 GO:0060038 cardiac muscle cell proliferation 1/435 60/18722 0.756536051890439 0.858506784436612 GJA1 1 GO:0071219 cellular response to molecule of bacterial origin 4/435 221/18722 0.758402678044884 0.860343390775958 GSTP1/PRDX2/ASS1/CD55 4 GO:0007409 axonogenesis 8/435 418/18722 0.758830983820489 0.860343390775958 BSG/NRP2/BMP7/APP/HSP90AB1/EFNA1/DAG1/LAMA5 8 GO:0007259 receptor signaling pathway via JAK-STAT 3/435 170/18722 0.75922736576178 0.860343390775958 IL10RB/AKR1B1/CAV1 3 GO:0030178 negative regulation of Wnt signaling pathway 3/435 170/18722 0.75922736576178 0.860343390775958 RNF43/FERMT1/CAV1 3 GO:0002702 positive regulation of production of molecular mediator of immune response 2/435 117/18722 0.759241627644591 0.860343390775958 CD55/PHB 2 GO:0019439 aromatic compound catabolic process 9/435 467/18722 0.76089502200439 0.861773361006116 COMT/SLIRP/LSM7/PNP/NUDT4/PON2/LIN28B/NPM1/SMPDL3A 9 GO:0015931 nucleobase-containing compound transport 4/435 222/18722 0.761487646959173 0.861773361006116 GJA1/NPM1/SLC19A1/CD47 4 GO:0019748 secondary metabolic process 1/435 61/18722 0.762211050145055 0.861773361006116 AKR1B1 1 GO:0050994 regulation of lipid catabolic process 1/435 61/18722 0.762211050145055 0.861773361006116 IDH1 1 GO:0060997 dendritic spine morphogenesis 1/435 61/18722 0.762211050145055 0.861773361006116 EFNA1 1 GO:0060998 regulation of dendritic spine development 1/435 61/18722 0.762211050145055 0.861773361006116 EFNA1 1 GO:2000401 regulation of lymphocyte migration 1/435 61/18722 0.762211050145055 0.861773361006116 APP 1 GO:0001654 eye development 7/435 371/18722 0.762245833591459 0.861773361006116 EFEMP1/SERPINF1/FBN2/BMP7/FBN1/TENM3/ATP2B1 7 GO:0042770 signal transduction in response to DNA damage 3/435 172/18722 0.766145289613373 0.865429804101444 MIF/NPM1/CCND1 3 GO:0008544 epidermis development 6/435 324/18722 0.767214433549329 0.865429804101444 SOD1/EGFR/DSP/LGR5/FERMT1/LAMA5 6 GO:0007091 metaphase/anaphase transition of mitotic cell cycle 1/435 62/18722 0.767754064623749 0.865429804101444 LCMT1 1 GO:0009116 nucleoside metabolic process 1/435 62/18722 0.767754064623749 0.865429804101444 PNP 1 GO:0010573 vascular endothelial growth factor production 1/435 62/18722 0.767754064623749 0.865429804101444 ADGRG1 1 GO:0031124 mRNA 3'-end processing 1/435 62/18722 0.767754064623749 0.865429804101444 APP 1 GO:0032731 positive regulation of interleukin-1 beta production 1/435 62/18722 0.767754064623749 0.865429804101444 APP 1 GO:0046148 pigment biosynthetic process 1/435 62/18722 0.767754064623749 0.865429804101444 TMEM14C 1 GO:0060113 inner ear receptor cell differentiation 1/435 62/18722 0.767754064623749 0.865429804101444 SOD1 1 GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 1/435 62/18722 0.767754064623749 0.865429804101444 BMP7 1 GO:0006816 calcium ion transport 8/435 422/18722 0.76788578271422 0.865429804101444 ANXA2/GJA1/LGALS3/STOML2/KCNN4/ATP2B1/TSPAN13/CAV1 8 GO:0030098 lymphocyte differentiation 7/435 374/18722 0.769386275973324 0.866874001715958 CTSL/SOD1/PRDX2/PNP/BAD/CD46/KDELR1 7 GO:0006304 DNA modification 2/435 120/18722 0.771472698539911 0.868235912435275 DNMT1/PARP1 2 GO:0032411 positive regulation of transporter activity 2/435 120/18722 0.771472698539911 0.868235912435275 NDUFA4/PARK7 2 GO:0048593 camera-type eye morphogenesis 2/435 120/18722 0.771472698539911 0.868235912435275 BMP7/TENM3 2 GO:0048675 axon extension 2/435 120/18722 0.771472698539911 0.868235912435275 NRP2/HSP90AB1 2 GO:0150063 visual system development 7/435 375/18722 0.771731413043359 0.868280125508266 EFEMP1/SERPINF1/FBN2/BMP7/FBN1/TENM3/ATP2B1 7 GO:0001947 heart looping 1/435 63/18722 0.773168157972552 0.868661669817544 FOLR1 1 GO:0031343 positive regulation of cell killing 1/435 63/18722 0.773168157972552 0.868661669817544 CADM1 1 GO:0099601 regulation of neurotransmitter receptor activity 1/435 63/18722 0.773168157972552 0.868661669817544 APP 1 GO:1902099 regulation of metaphase/anaphase transition of cell cycle 1/435 63/18722 0.773168157972552 0.868661669817544 LCMT1 1 GO:2000756 regulation of peptidyl-lysine acetylation 1/435 63/18722 0.773168157972552 0.868661669817544 PARK7 1 GO:0048706 embryonic skeletal system development 2/435 121/18722 0.775427853250741 0.870953169262896 BMP7/SLC39A1 2 GO:0030837 negative regulation of actin filament polymerization 1/435 64/18722 0.778456321929996 0.87235689655545 KANK4 1 GO:0045670 regulation of osteoclast differentiation 1/435 64/18722 0.778456321929996 0.87235689655545 FBN1 1 GO:0046579 positive regulation of Ras protein signal transduction 1/435 64/18722 0.778456321929996 0.87235689655545 ADGRG1 1 GO:0046854 phosphatidylinositol phosphate biosynthetic process 1/435 64/18722 0.778456321929996 0.87235689655545 TMEM150A 1 GO:0046888 negative regulation of hormone secretion 1/435 64/18722 0.778456321929996 0.87235689655545 GJA1 1 GO:0098930 axonal transport 1/435 64/18722 0.778456321929996 0.87235689655545 SOD1 1 GO:1900076 regulation of cellular response to insulin stimulus 1/435 64/18722 0.778456321929996 0.87235689655545 ATP2B1 1 GO:1903018 regulation of glycoprotein metabolic process 1/435 64/18722 0.778456321929996 0.87235689655545 TMEM59 1 GO:0019730 antimicrobial humoral response 2/435 122/18722 0.779323130989011 0.87235689655545 RPS19/ROMO1 2 GO:0031109 microtubule polymerization or depolymerization 2/435 122/18722 0.779323130989011 0.87235689655545 MET/RPS3 2 GO:0050868 negative regulation of T cell activation 2/435 122/18722 0.779323130989011 0.87235689655545 PRDX2/LGALS3 2 GO:0051208 sequestering of calcium ion 2/435 122/18722 0.779323130989011 0.87235689655545 HSP90B1/CALR 2 GO:0071695 anatomical structure maturation 4/435 229/18722 0.782232404987272 0.875187748310694 APP/AKR1B1/DAG1/FERMT1 4 GO:0002720 positive regulation of cytokine production involved in immune response 1/435 65/18722 0.783621478965072 0.875187748310694 CD55 1 GO:0010965 regulation of mitotic sister chromatid separation 1/435 65/18722 0.783621478965072 0.875187748310694 LCMT1 1 GO:0044784 metaphase/anaphase transition of cell cycle 1/435 65/18722 0.783621478965072 0.875187748310694 LCMT1 1 GO:0045453 bone resorption 1/435 65/18722 0.783621478965072 0.875187748310694 EGFR 1 GO:0046503 glycerolipid catabolic process 1/435 65/18722 0.783621478965072 0.875187748310694 PRDX6 1 GO:0060389 pathway-restricted SMAD protein phosphorylation 1/435 65/18722 0.783621478965072 0.875187748310694 BMP7 1 GO:0070936 protein K48-linked ubiquitination 1/435 65/18722 0.783621478965072 0.875187748310694 SKP2 1 GO:0016197 endosomal transport 4/435 230/18722 0.7850760235605 0.876564849105219 TINAGL1/NSG1/SNX3/RAB17 4 GO:0048880 sensory system development 7/435 381/18722 0.785436490792577 0.876719941908668 EFEMP1/SERPINF1/FBN2/BMP7/FBN1/TENM3/ATP2B1 7 GO:0048015 phosphatidylinositol-mediated signaling 3/435 178/18722 0.785933517545516 0.877027334722958 EGFR/C1QBP/MYDGF 3 GO:0001909 leukocyte mediated cytotoxicity 2/435 124/18722 0.786936616357207 0.877404393047469 PRDX1/CADM1 2 GO:0007368 determination of left/right symmetry 2/435 124/18722 0.786936616357207 0.877404393047469 GALNT11/FOLR1 2 GO:0009132 nucleoside diphosphate metabolic process 2/435 124/18722 0.786936616357207 0.877404393047469 APP/BAD 2 GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 1/435 66/18722 0.788666483877448 0.877583689340071 HSPD1 1 GO:0016444 somatic cell DNA recombination 1/435 66/18722 0.788666483877448 0.877583689340071 HSPD1 1 GO:0051893 regulation of focal adhesion assembly 1/435 66/18722 0.788666483877448 0.877583689340071 S100A10 1 GO:0072678 T cell migration 1/435 66/18722 0.788666483877448 0.877583689340071 APP 1 GO:0090109 regulation of cell-substrate junction assembly 1/435 66/18722 0.788666483877448 0.877583689340071 S100A10 1 GO:1905953 negative regulation of lipid localization 1/435 66/18722 0.788666483877448 0.877583689340071 FIS1 1 GO:0007416 synapse assembly 3/435 179/18722 0.789093446214802 0.877583689340071 CDH1/APP/RAB17 3 GO:0007626 locomotory behavior 3/435 179/18722 0.789093446214802 0.877583689340071 SOD1/APP/PARK7 3 GO:1901991 negative regulation of mitotic cell cycle phase transition 3/435 179/18722 0.789093446214802 0.877583689340071 CTDSPL/CCND1/LCMT1 3 GO:0055007 cardiac muscle cell differentiation 2/435 125/18722 0.790656110592361 0.878848242055714 CALR/LMNA 2 GO:0032271 regulation of protein polymerization 4/435 232/18722 0.790674688329123 0.878848242055714 MET/RPS3/KANK4/WASF2 4 GO:0016049 cell growth 9/435 482/18722 0.791862179485488 0.879622396093183 EGFR/NRP2/NDUFA13/APP/GJA1/HSP90AB1/PHB/RBBP7/NPM1 9 GO:0006879 cellular iron ion homeostasis 1/435 67/18722 0.793594125360794 0.879622396093183 SOD1 1 GO:0016445 somatic diversification of immunoglobulins 1/435 67/18722 0.793594125360794 0.879622396093183 HSPD1 1 GO:0042490 mechanoreceptor differentiation 1/435 67/18722 0.793594125360794 0.879622396093183 SOD1 1 GO:0051306 mitotic sister chromatid separation 1/435 67/18722 0.793594125360794 0.879622396093183 LCMT1 1 GO:0061180 mammary gland epithelium development 1/435 67/18722 0.793594125360794 0.879622396093183 CCND1 1 GO:0061371 determination of heart left/right asymmetry 1/435 67/18722 0.793594125360794 0.879622396093183 FOLR1 1 GO:0070527 platelet aggregation 1/435 67/18722 0.793594125360794 0.879622396093183 GNAS 1 GO:0072665 protein localization to vacuole 1/435 67/18722 0.793594125360794 0.879622396093183 LAMTOR5 1 GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 1/435 67/18722 0.793594125360794 0.879622396093183 CD55 1 GO:0045766 positive regulation of angiogenesis 3/435 181/18722 0.795297349347357 0.880770112333471 ANXA3/MYDGF/PDCD6 3 GO:0097696 receptor signaling pathway via STAT 3/435 181/18722 0.795297349347357 0.880770112333471 IL10RB/AKR1B1/CAV1 3 GO:1904018 positive regulation of vasculature development 3/435 181/18722 0.795297349347357 0.880770112333471 ANXA3/MYDGF/PDCD6 3 GO:0007389 pattern specification process 8/435 436/18722 0.797649258282756 0.881992463326782 ADGRG1/GALNT11/NRP2/FOLR1/BMP7/LRP2/WLS/NR2F2 8 GO:0048565 digestive tract development 2/435 127/18722 0.797923832507603 0.881992463326782 EGFR/ASS1 2 GO:0048017 inositol lipid-mediated signaling 3/435 182/18722 0.798341882525123 0.881992463326782 EGFR/C1QBP/MYDGF 3 GO:0009247 glycolipid biosynthetic process 1/435 68/18722 0.798407127530081 0.881992463326782 PYURF 1 GO:0032922 circadian regulation of gene expression 1/435 68/18722 0.798407127530081 0.881992463326782 MAGED1 1 GO:0046637 regulation of alpha-beta T cell differentiation 1/435 68/18722 0.798407127530081 0.881992463326782 PNP 1 GO:0051148 negative regulation of muscle cell differentiation 1/435 68/18722 0.798407127530081 0.881992463326782 DNMT1 1 GO:1901016 regulation of potassium ion transmembrane transporter activity 1/435 68/18722 0.798407127530081 0.881992463326782 CAV1 1 GO:1902305 regulation of sodium ion transmembrane transport 1/435 68/18722 0.798407127530081 0.881992463326782 FXYD3 1 GO:0002819 regulation of adaptive immune response 3/435 183/18722 0.801348515041755 0.884939207609806 HSPD1/CD46/CD55 3 GO:0090068 positive regulation of cell cycle process 4/435 236/18722 0.801521890339536 0.884939207609806 EGFR/APP/NPM1/CCND1 4 GO:0003143 embryonic heart tube morphogenesis 1/435 69/18722 0.803108151413668 0.885455267524069 FOLR1 1 GO:0006368 transcription elongation from RNA polymerase II promoter 1/435 69/18722 0.803108151413668 0.885455267524069 POLR2I 1 GO:0019226 transmission of nerve impulse 1/435 69/18722 0.803108151413668 0.885455267524069 SOD1 1 GO:0033344 cholesterol efflux 1/435 69/18722 0.803108151413668 0.885455267524069 CAV1 1 GO:0050688 regulation of defense response to virus 1/435 69/18722 0.803108151413668 0.885455267524069 C1QBP 1 GO:0050804 modulation of chemical synaptic transmission 8/435 439/18722 0.803641117848795 0.885796073350329 EGFR/CDH1/MME/APP/CLN3/SLC6A4/NSG1/S1PR2 8 GO:0055001 muscle cell development 3/435 184/18722 0.804317534624212 0.886294760375385 KRT8/CSRP2/LMNA 3 GO:1901987 regulation of cell cycle phase transition 7/435 390/18722 0.804831165762031 0.886517248961049 EGFR/APP/CTDSPL/NPM1/DDB1/CCND1/LCMT1 7 GO:0007093 mitotic cell cycle checkpoint signaling 2/435 129/18722 0.804967519716211 0.886517248961049 CCND1/LCMT1 2 GO:0099177 regulation of trans-synaptic signaling 8/435 440/18722 0.805608503113393 0.886976306850221 EGFR/CDH1/MME/APP/CLN3/SLC6A4/NSG1/S1PR2 8 GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response 1/435 70/18722 0.80769979641099 0.888537140505501 HSPD1 1 GO:0003407 neural retina development 1/435 70/18722 0.80769979641099 0.888537140505501 ATP2B1 1 GO:0045123 cellular extravasation 1/435 70/18722 0.80769979641099 0.888537140505501 CD47 1 GO:0016236 macroautophagy 5/435 291/18722 0.809527828150356 0.890070641373696 VAMP8/CLN3/ATP6V1B1/SCOC/BNIP3 5 GO:0045765 regulation of angiogenesis 6/435 342/18722 0.809543653854924 0.890070641373696 SERPINF1/ANXA3/EFNA1/MYDGF/AMOT/PDCD6 6 GO:0022411 cellular component disassembly 8/435 443/18722 0.811421486048175 0.891240839986909 VAMP8/RPL23/CLN3/PARK7/HMGA1/FIS1/DSTN/BNIP3 8 GO:0051960 regulation of nervous system development 8/435 443/18722 0.811421486048175 0.891240839986909 SERPINF1/SPINT1/EGFR/BMP7/LRP2/TGM2/MME/DAG1 8 GO:0006661 phosphatidylinositol biosynthetic process 2/435 131/18722 0.811792363412669 0.891240839986909 TMEM150A/PYURF 2 GO:0045089 positive regulation of innate immune response 2/435 131/18722 0.811792363412669 0.891240839986909 RPS19/CADM1 2 GO:0032722 positive regulation of chemokine production 1/435 71/18722 0.812184601716653 0.891240839986909 APP 1 GO:0045824 negative regulation of innate immune response 1/435 71/18722 0.812184601716653 0.891240839986909 RPS19 1 GO:0150116 regulation of cell-substrate junction organization 1/435 71/18722 0.812184601716653 0.891240839986909 S100A10 1 GO:0008064 regulation of actin polymerization or depolymerization 3/435 187/18722 0.813001836570208 0.89189028758201 DSTN/KANK4/WASF2 3 GO:0006813 potassium ion transport 4/435 241/18722 0.814437402408783 0.892335789504313 FXYD3/GJA5/KCNN4/CAV1 4 GO:0044843 cell cycle G1/S phase transition 4/435 241/18722 0.814437402408783 0.892335789504313 EGFR/CTDSPL/SKP2/CCND1 4 GO:0046700 heterocycle catabolic process 8/435 445/18722 0.815222902529889 0.892335789504313 QPRT/SLIRP/LSM7/PNP/NUDT4/LIN28B/NPM1/SMPDL3A 8 GO:0030832 regulation of actin filament length 3/435 188/18722 0.815823338383546 0.892335789504313 DSTN/KANK4/WASF2 3 GO:0048839 inner ear development 3/435 188/18722 0.815823338383546 0.892335789504313 SOD1/LGR5/ATP6V1B1 3 GO:1901361 organic cyclic compound catabolic process 9/435 495/18722 0.816238420464346 0.892335789504313 COMT/QPRT/SLIRP/LSM7/PNP/NUDT4/LIN28B/NPM1/SMPDL3A 9 GO:0030032 lamellipodium assembly 1/435 72/18722 0.81656504771168 0.892335789504313 WASF2 1 GO:0032729 positive regulation of interferon-gamma production 1/435 72/18722 0.81656504771168 0.892335789504313 HSPD1 1 GO:0033045 regulation of sister chromatid segregation 1/435 72/18722 0.81656504771168 0.892335789504313 LCMT1 1 GO:0042246 tissue regeneration 1/435 72/18722 0.81656504771168 0.892335789504313 DAG1 1 GO:0050709 negative regulation of protein secretion 1/435 72/18722 0.81656504771168 0.892335789504313 ERP29 1 GO:0055021 regulation of cardiac muscle tissue growth 1/435 72/18722 0.81656504771168 0.892335789504313 GJA1 1 GO:0071479 cellular response to ionizing radiation 1/435 72/18722 0.81656504771168 0.892335789504313 GTF2H5 1 GO:1905818 regulation of chromosome separation 1/435 72/18722 0.81656504771168 0.892335789504313 LCMT1 1 GO:0006997 nucleus organization 2/435 133/18722 0.818403551617207 0.893851187896574 RPS19/LMNA 2 GO:0009855 determination of bilateral symmetry 2/435 133/18722 0.818403551617207 0.893851187896574 GALNT11/FOLR1 2 GO:0016358 dendrite development 4/435 243/18722 0.819407675659433 0.894167341310877 BMP7/APP/EFNA1/RAB17 4 GO:0002637 regulation of immunoglobulin production 1/435 73/18722 0.820843557322695 0.894167341310877 PHB 1 GO:0035924 cellular response to vascular endothelial growth factor stimulus 1/435 73/18722 0.820843557322695 0.894167341310877 NRP2 1 GO:0051145 smooth muscle cell differentiation 1/435 73/18722 0.820843557322695 0.894167341310877 DNMT1 1 GO:0051298 centrosome duplication 1/435 73/18722 0.820843557322695 0.894167341310877 NPM1 1 GO:0051865 protein autoubiquitination 1/435 73/18722 0.820843557322695 0.894167341310877 RNF181 1 GO:0061035 regulation of cartilage development 1/435 73/18722 0.820843557322695 0.894167341310877 EFEMP1 1 GO:0099518 vesicle cytoskeletal trafficking 1/435 73/18722 0.820843557322695 0.894167341310877 CLN3 1 GO:0051258 protein polymerization 5/435 296/18722 0.820961210073546 0.894167341310877 MET/RPS3/MSRB2/KANK4/WASF2 5 GO:0030041 actin filament polymerization 3/435 190/18722 0.821358244473727 0.894167341310877 MSRB2/KANK4/WASF2 3 GO:0099111 microtubule-based transport 3/435 190/18722 0.821358244473727 0.894167341310877 SOD1/APP/CLN3 3 GO:0008277 regulation of G protein-coupled receptor signaling pathway 2/435 134/18722 0.821630642660184 0.894167341310877 MET/PHB 2 GO:0009799 specification of symmetry 2/435 134/18722 0.821630642660184 0.894167341310877 GALNT11/FOLR1 2 GO:1901342 regulation of vasculature development 6/435 348/18722 0.822243058096693 0.894587786881664 SERPINF1/ANXA3/EFNA1/MYDGF/AMOT/PDCD6 6 GO:0042157 lipoprotein metabolic process 2/435 135/18722 0.824806258538415 0.896133412575618 DBI/PYURF 2 GO:0002437 inflammatory response to antigenic stimulus 1/435 74/18722 0.825022497349754 0.896133412575618 PARK7 1 GO:0007040 lysosome organization 1/435 74/18722 0.825022497349754 0.896133412575618 CLN3 1 GO:0046323 glucose import 1/435 74/18722 0.825022497349754 0.896133412575618 SLC2A1 1 GO:0080171 lytic vacuole organization 1/435 74/18722 0.825022497349754 0.896133412575618 CLN3 1 GO:1901568 fatty acid derivative metabolic process 1/435 74/18722 0.825022497349754 0.896133412575618 TECR 1 GO:0044270 cellular nitrogen compound catabolic process 8/435 451/18722 0.826276259063007 0.897055177258349 QPRT/SLIRP/LSM7/PNP/NUDT4/LIN28B/NPM1/SMPDL3A 8 GO:0002449 lymphocyte mediated immunity 6/435 350/18722 0.826324518854355 0.897055177258349 PRDX1/HSPD1/C1QBP/CD46/CADM1/CD55 6 GO:0071216 cellular response to biotic stimulus 4/435 246/18722 0.826657515543794 0.897170540045747 GSTP1/PRDX2/ASS1/CD55 4 GO:0045727 positive regulation of translation 2/435 136/18722 0.827931042285604 0.897855839990271 C1QBP/NPM1 2 GO:0002292 T cell differentiation involved in immune response 1/435 75/18722 0.829104179763571 0.897855839990271 CD46 1 GO:0006024 glycosaminoglycan biosynthetic process 1/435 75/18722 0.829104179763571 0.897855839990271 CHPF 1 GO:0006094 gluconeogenesis 1/435 75/18722 0.829104179763571 0.897855839990271 DDB1 1 GO:0033077 T cell differentiation in thymus 1/435 75/18722 0.829104179763571 0.897855839990271 SOD1 1 GO:0034121 regulation of toll-like receptor signaling pathway 1/435 75/18722 0.829104179763571 0.897855839990271 CAV1 1 GO:0051453 regulation of intracellular pH 1/435 75/18722 0.829104179763571 0.897855839990271 CLN3 1 GO:1902369 negative regulation of RNA catabolic process 1/435 75/18722 0.829104179763571 0.897855839990271 SLIRP 1 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 3/435 193/18722 0.829394928575325 0.897924960977445 CD24/EFNA1/MIF 3 GO:0007586 digestion 2/435 137/18722 0.831005634915394 0.899176728837904 KCNN4/LPCAT3 2 GO:0090090 negative regulation of canonical Wnt signaling pathway 2/435 137/18722 0.831005634915394 0.899176728837904 FERMT1/CAV1 2 GO:0002285 lymphocyte activation involved in immune response 3/435 194/18722 0.83200420651277 0.899710847375394 HSPD1/LGALS3/CD46 3 GO:0031346 positive regulation of cell projection organization 6/435 353/18722 0.832306822009434 0.899710847375394 SERPINF1/ITGA6/BMP7/TENM3/SNX3/WASF2 6 GO:0009123 nucleoside monophosphate metabolic process 1/435 76/18722 0.833090862972819 0.899710847375394 PNP 1 GO:0014855 striated muscle cell proliferation 1/435 76/18722 0.833090862972819 0.899710847375394 GJA1 1 GO:0032720 negative regulation of tumor necrosis factor production 1/435 76/18722 0.833090862972819 0.899710847375394 GSTP1 1 GO:0071426 ribonucleoprotein complex export from nucleus 1/435 76/18722 0.833090862972819 0.899710847375394 NPM1 1 GO:0140029 exocytic process 1/435 76/18722 0.833090862972819 0.899710847375394 VAMP8 1 GO:0035107 appendage morphogenesis 2/435 138/18722 0.834030675168438 0.900234419433036 FBN2/BMP7 2 GO:0035108 limb morphogenesis 2/435 138/18722 0.834030675168438 0.900234419433036 FBN2/BMP7 2 GO:0030705 cytoskeleton-dependent intracellular transport 3/435 195/18722 0.834579192612036 0.900580819516179 SOD1/APP/CLN3 3 GO:0010959 regulation of metal ion transport 7/435 406/18722 0.835963480504523 0.901479560348498 FXYD3/GJA1/LGALS3/KCNN4/ATP2B1/TSPAN13/CAV1 7 GO:0000380 alternative mRNA splicing, via spliceosome 1/435 77/18722 0.836984753062212 0.901479560348498 MBNL3 1 GO:0002200 somatic diversification of immune receptors 1/435 77/18722 0.836984753062212 0.901479560348498 HSPD1 1 GO:0007492 endoderm development 1/435 77/18722 0.836984753062212 0.901479560348498 ITGB5 1 GO:0071166 ribonucleoprotein complex localization 1/435 77/18722 0.836984753062212 0.901479560348498 NPM1 1 GO:1901983 regulation of protein acetylation 1/435 77/18722 0.836984753062212 0.901479560348498 PARK7 1 GO:0045598 regulation of fat cell differentiation 2/435 139/18722 0.837006799272272 0.901479560348498 ADIRF/BMP7 2 GO:0034655 nucleobase-containing compound catabolic process 7/435 407/18722 0.837771314981467 0.902057440375963 SLIRP/LSM7/PNP/NUDT4/LIN28B/NPM1/SMPDL3A 7 GO:0042594 response to starvation 3/435 197/18722 0.839627536893007 0.903810164169105 PAGE4/SLC2A1/COMT 3 GO:0035050 embryonic heart tube development 1/435 78/18722 0.840788005002031 0.904321319867637 FOLR1 1 GO:1901616 organic hydroxy compound catabolic process 1/435 78/18722 0.840788005002031 0.904321319867637 COMT 1 GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 1/435 78/18722 0.840788005002031 0.904321319867637 GSTP1 1 GO:0006325 chromatin organization 7/435 409/18722 0.841339567483921 0.904668659927683 DNMT1/HMGA1/HMGN3/RBBP7/CBX4/ZNHIT1/NPM1 7 GO:0050864 regulation of B cell activation 3/435 198/18722 0.84210152111874 0.905241977469941 SLC39A10/BAD/MIF 3 GO:0006023 aminoglycan biosynthetic process 1/435 79/18722 0.844502723829757 0.906837795982184 CHPF 1 GO:0006446 regulation of translational initiation 1/435 79/18722 0.844502723829757 0.906837795982184 NPM1 1 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 1/435 79/18722 0.844502723829757 0.906837795982184 MYDGF 1 GO:0032272 negative regulation of protein polymerization 1/435 79/18722 0.844502723829757 0.906837795982184 KANK4 1 GO:0016570 histone modification 8/435 463/18722 0.846839546784045 0.908997126137699 DNMT1/PARK7/LMNA/PHB/TBL1X/DDB1/TRMT112/PRMT1 8 GO:0043547 positive regulation of GTPase activity 4/435 255/18722 0.846973061427772 0.908997126137699 ITGA6/TGM2/ADRB1/S100A10 4 GO:0070555 response to interleukin-1 2/435 143/18722 0.848434758359861 0.91031896389099 APP/CD47 2 GO:0065004 protein-DNA complex assembly 3/435 201/18722 0.849326492709756 0.911028715546898 GTF2H5/GTF2A2/NPM1 3 GO:0006096 glycolytic process 1/435 81/18722 0.851674739534464 0.912558067787131 APP 1 GO:0030641 regulation of cellular pH 1/435 81/18722 0.851674739534464 0.912558067787131 CLN3 1 GO:0044773 mitotic DNA damage checkpoint signaling 1/435 81/18722 0.851674739534464 0.912558067787131 CCND1 1 GO:2000243 positive regulation of reproductive process 1/435 81/18722 0.851674739534464 0.912558067787131 C1QBP 1 GO:0032869 cellular response to insulin stimulus 3/435 203/18722 0.853982140670594 0.914286187520299 GSTP1/PARP1/ATP2B1 3 GO:0016311 dephosphorylation 7/435 417/18722 0.854991071124355 0.914286187520299 HSP90B1/DUSP14/HSP90AB1/CTDSPL/SLC39A10/LGALS3/PHPT1 7 GO:0001910 regulation of leukocyte mediated cytotoxicity 1/435 82/18722 0.855136007079258 0.914286187520299 CADM1 1 GO:0002312 B cell activation involved in immune response 1/435 82/18722 0.855136007079258 0.914286187520299 HSPD1 1 GO:0006757 ATP generation from ADP 1/435 82/18722 0.855136007079258 0.914286187520299 APP 1 GO:0007032 endosome organization 1/435 82/18722 0.855136007079258 0.914286187520299 SNX3 1 GO:0050000 chromosome localization 1/435 82/18722 0.855136007079258 0.914286187520299 LMNA 1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic 1/435 82/18722 0.855136007079258 0.914286187520299 RPS21 1 GO:0001510 RNA methylation 1/435 83/18722 0.858516685025638 0.917404948054672 TRMT112 1 GO:0043367 CD4-positive, alpha-beta T cell differentiation 1/435 83/18722 0.858516685025638 0.917404948054672 CTSL 1 GO:0060041 retina development in camera-type eye 2/435 147/18722 0.859130158945288 0.917812645503916 SERPINF1/ATP2B1 2 GO:0090305 nucleic acid phosphodiester bond hydrolysis 4/435 261/18722 0.859373092272483 0.917824379520166 RPS21/NHP2/REXO2/POLR2I 4 GO:0050905 neuromuscular process 2/435 148/18722 0.861694149553719 0.918948094960643 APP/CLN3 2 GO:0070507 regulation of microtubule cytoskeleton organization 2/435 148/18722 0.861694149553719 0.918948094960643 MET/RPS3 2 GO:0006405 RNA export from nucleus 1/435 84/18722 0.861818645539284 0.918948094960643 NPM1 1 GO:0042440 pigment metabolic process 1/435 84/18722 0.861818645539284 0.918948094960643 TMEM14C 1 GO:0045445 myoblast differentiation 1/435 84/18722 0.861818645539284 0.918948094960643 MBNL3 1 GO:0097061 dendritic spine organization 1/435 84/18722 0.861818645539284 0.918948094960643 EFNA1 1 GO:0016525 negative regulation of angiogenesis 2/435 149/18722 0.864215403510819 0.920402793686485 SERPINF1/AMOT 2 GO:0010507 negative regulation of autophagy 1/435 85/18722 0.865043717391973 0.920402793686485 MET 1 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 1/435 85/18722 0.865043717391973 0.920402793686485 CAV1 1 GO:0044774 mitotic DNA integrity checkpoint signaling 1/435 85/18722 0.865043717391973 0.920402793686485 CCND1 1 GO:0055013 cardiac muscle cell development 1/435 85/18722 0.865043717391973 0.920402793686485 LMNA 1 GO:0055072 iron ion homeostasis 1/435 85/18722 0.865043717391973 0.920402793686485 SOD1 1 GO:0072384 organelle transport along microtubule 1/435 85/18722 0.865043717391973 0.920402793686485 CLN3 1 GO:2000779 regulation of double-strand break repair 1/435 85/18722 0.865043717391973 0.920402793686485 PARP1 1 GO:0044772 mitotic cell cycle phase transition 7/435 424/18722 0.866143163552719 0.921324865101642 EGFR/APP/CTDSPL/SKP2/DDB1/CCND1/LCMT1 7 GO:0006493 protein O-linked glycosylation 1/435 86/18722 0.868193686965106 0.922266421294208 GALNT11 1 GO:0009798 axis specification 1/435 86/18722 0.868193686965106 0.922266421294208 WLS 1 GO:0032413 negative regulation of ion transmembrane transporter activity 1/435 86/18722 0.868193686965106 0.922266421294208 CAV1 1 GO:0034103 regulation of tissue remodeling 1/435 86/18722 0.868193686965106 0.922266421294208 EGFR 1 GO:0045921 positive regulation of exocytosis 1/435 86/18722 0.868193686965106 0.922266421294208 VAMP8 1 GO:2000181 negative regulation of blood vessel morphogenesis 2/435 151/18722 0.86913208077468 0.922837375908008 SERPINF1/AMOT 2 GO:1903131 mononuclear cell differentiation 7/435 426/18722 0.869197599193618 0.922837375908008 CTSL/SOD1/PRDX2/PNP/BAD/CD46/KDELR1 7 GO:0032412 regulation of ion transmembrane transporter activity 4/435 267/18722 0.87090755612154 0.924046254101703 FXYD3/APP/NDUFA4/CAV1 4 GO:0048041 focal adhesion assembly 1/435 87/18722 0.871270299230087 0.924046254101703 S100A10 1 GO:0051262 protein tetramerization 1/435 87/18722 0.871270299230087 0.924046254101703 SSBP1 1 GO:1901879 regulation of protein depolymerization 1/435 87/18722 0.871270299230087 0.924046254101703 DSTN 1 GO:1901343 negative regulation of vasculature development 2/435 152/18722 0.871528682248788 0.924072614056392 SERPINF1/AMOT 2 GO:0007260 tyrosine phosphorylation of STAT protein 1/435 88/18722 0.874275258706068 0.926240213842011 CAV1 1 GO:0030101 natural killer cell activation 1/435 88/18722 0.874275258706068 0.926240213842011 PRDX1 1 GO:0050779 RNA destabilization 1/435 88/18722 0.874275258706068 0.926240213842011 LIN28B 1 GO:0043583 ear development 3/435 213/18722 0.875422954317266 0.927207877471473 SOD1/LGR5/ATP6V1B1 3 GO:0046330 positive regulation of JNK cascade 1/435 89/18722 0.877210230395607 0.928852256268509 APP 1 GO:0007519 skeletal muscle tissue development 2/435 155/18722 0.878478507069251 0.929946348976198 NR2F2/CAV1 2 GO:0007601 visual perception 3/435 215/18722 0.87936120310219 0.930145314808984 EFEMP1/TACSTD2/DNAJC19 3 GO:0002028 regulation of sodium ion transport 1/435 90/18722 0.88007684069872 0.930145314808984 FXYD3 1 GO:0006400 tRNA modification 1/435 90/18722 0.88007684069872 0.930145314808984 TRMT112 1 GO:0048477 oogenesis 1/435 90/18722 0.88007684069872 0.930145314808984 LGR5 1 GO:0070664 negative regulation of leukocyte proliferation 1/435 90/18722 0.88007684069872 0.930145314808984 GSTP1 1 GO:0097581 lamellipodium organization 1/435 90/18722 0.88007684069872 0.930145314808984 WASF2 1 GO:0009267 cellular response to starvation 2/435 156/18722 0.880717029340587 0.930573373858666 SLC2A1/COMT 2 GO:0002065 columnar/cuboidal epithelial cell differentiation 1/435 91/18722 0.882876678305851 0.931157875286222 BAD 1 GO:0019935 cyclic-nucleotide-mediated signaling 1/435 91/18722 0.882876678305851 0.931157875286222 NUDT4 1 GO:0042147 retrograde transport, endosome to Golgi 1/435 91/18722 0.882876678305851 0.931157875286222 SNX3 1 GO:0051983 regulation of chromosome segregation 1/435 91/18722 0.882876678305851 0.931157875286222 LCMT1 1 GO:0055006 cardiac cell development 1/435 91/18722 0.882876678305851 0.931157875286222 LMNA 1 GO:0098661 inorganic anion transmembrane transport 1/435 91/18722 0.882876678305851 0.931157875286222 SLC25A3 1 GO:0051250 negative regulation of lymphocyte activation 2/435 157/18722 0.882917449601694 0.931157875286222 PRDX2/LGALS3 2 GO:0022412 cellular process involved in reproduction in multicellular organism 6/435 384/18722 0.88489648303292 0.932921812838356 FOLR1/SPESP1/PRDX4/SLIRP/LGR5/EIF2S2 6 GO:0045088 regulation of innate immune response 3/435 218/18722 0.885061532826684 0.932921812838356 RPS19/HSP90AB1/CADM1 3 GO:0001708 cell fate specification 1/435 92/18722 0.88561129507022 0.933004231787236 LMO4 1 GO:0070509 calcium ion import 1/435 92/18722 0.88561129507022 0.933004231787236 LGALS3 1 GO:0003002 regionalization 5/435 331/18722 0.886270098899738 0.933449768790594 ADGRG1/NRP2/LRP2/WLS/NR2F2 5 GO:0050953 sensory perception of light stimulus 3/435 219/18722 0.886907658017374 0.933872698982105 EFEMP1/TACSTD2/DNAJC19 3 GO:0046488 phosphatidylinositol metabolic process 2/435 159/18722 0.88720620635587 0.933938536459212 TMEM150A/PYURF 2 GO:0060349 bone morphogenesis 1/435 93/18722 0.888282206860045 0.934822524613085 MSX2 1 GO:0031503 protein-containing complex localization 3/435 220/18722 0.888727298400087 0.935042254658108 DAG1/NSG1/NPM1 3 GO:0006401 RNA catabolic process 4/435 278/18722 0.889949193025043 0.936078935885193 SLIRP/LSM7/LIN28B/NPM1 4 GO:0042113 B cell activation 5/435 334/18722 0.890779623058749 0.936571538019541 HSPD1/SLC39A10/BAD/MIF/PHB 5 GO:0001738 morphogenesis of a polarized epithelium 1/435 94/18722 0.890890894391093 0.936571538019541 LAMA5 1 GO:0021700 developmental maturation 4/435 280/18722 0.893135133944624 0.938253011567486 APP/AKR1B1/DAG1/FERMT1 4 GO:0032479 regulation of type I interferon production 1/435 95/18722 0.893438804040002 0.938253011567486 HSPD1 1 GO:0032606 type I interferon production 1/435 95/18722 0.893438804040002 0.938253011567486 HSPD1 1 GO:0045666 positive regulation of neuron differentiation 1/435 95/18722 0.893438804040002 0.938253011567486 BMP7 1 GO:0010975 regulation of neuron projection development 7/435 445/18722 0.895448000547386 0.939370566657101 SERPINF1/ITGA6/BMP7/EFNA1/TENM3/SNX3/RAB17 7 GO:0002718 regulation of cytokine production involved in immune response 1/435 96/18722 0.895927348638842 0.939370566657101 CD55 1 GO:0035282 segmentation 1/435 96/18722 0.895927348638842 0.939370566657101 NRP2 1 GO:0051304 chromosome separation 1/435 96/18722 0.895927348638842 0.939370566657101 LCMT1 1 GO:0055017 cardiac muscle tissue growth 1/435 96/18722 0.895927348638842 0.939370566657101 GJA1 1 GO:1904035 regulation of epithelial cell apoptotic process 1/435 96/18722 0.895927348638842 0.939370566657101 BAD 1 GO:0002700 regulation of production of molecular mediator of immune response 2/435 164/18722 0.897299645878413 0.940560185096922 CD55/PHB 2 GO:0051146 striated muscle cell differentiation 4/435 283/18722 0.897762673230923 0.940796318319588 KRT8/CSRP2/CALR/LMNA 4 GO:0035335 peptidyl-tyrosine dephosphorylation 1/435 97/18722 0.898357908251325 0.94092171597419 DUSP14 1 GO:0043255 regulation of carbohydrate biosynthetic process 1/435 97/18722 0.898357908251325 0.94092171597419 DDB1 1 GO:0002367 cytokine production involved in immune response 1/435 98/18722 0.900731830931092 0.942908956347707 CD55 1 GO:0043473 pigmentation 1/435 98/18722 0.900731830931092 0.942908956347707 RAB17 1 GO:0009451 RNA modification 2/435 167/18722 0.902945920699397 0.943339642347181 NHP2/TRMT112 2 GO:0034767 positive regulation of ion transmembrane transport 2/435 167/18722 0.902945920699397 0.943339642347181 NDUFA4/KCNN4 2 GO:0006165 nucleoside diphosphate phosphorylation 1/435 99/18722 0.903050433462502 0.943339642347181 APP 1 GO:0007631 feeding behavior 1/435 99/18722 0.903050433462502 0.943339642347181 APP 1 GO:0021510 spinal cord development 1/435 99/18722 0.903050433462502 0.943339642347181 LMO4 1 GO:0021549 cerebellum development 1/435 99/18722 0.903050433462502 0.943339642347181 UQCRQ 1 GO:0030838 positive regulation of actin filament polymerization 1/435 99/18722 0.903050433462502 0.943339642347181 WASF2 1 GO:0060996 dendritic spine development 1/435 99/18722 0.903050433462502 0.943339642347181 EFNA1 1 GO:0016482 cytosolic transport 2/435 168/18722 0.904762795896281 0.944685850862524 CLN3/SNX3 2 GO:1903311 regulation of mRNA metabolic process 4/435 288/18722 0.905084686356601 0.944685850862524 MBNL3/PRDX6/C1QBP/NPM1 4 GO:0006641 triglyceride metabolic process 1/435 100/18722 0.905315002084304 0.944685850862524 CAV1 1 GO:0006910 phagocytosis, recognition 1/435 100/18722 0.905315002084304 0.944685850862524 COLEC12 1 GO:0045055 regulated exocytosis 3/435 230/18722 0.90553283606812 0.944685850862524 VAMP8/ANXA3/S100A13 3 GO:0000075 cell cycle checkpoint signaling 2/435 169/18722 0.906547895751883 0.945495525432315 CCND1/LCMT1 2 GO:0046939 nucleotide phosphorylation 1/435 101/18722 0.907526793196608 0.946017787323229 APP 1 GO:0050830 defense response to Gram-positive bacterium 1/435 101/18722 0.907526793196608 0.946017787323229 ROMO1 1 GO:0043487 regulation of RNA stability 2/435 170/18722 0.908301711585099 0.946576210888132 LIN28B/NPM1 2 GO:0010522 regulation of calcium ion transport into cytosol 1/435 102/18722 0.909687034051529 0.947623119225231 CAV1 1 GO:0030833 regulation of actin filament polymerization 2/435 171/18722 0.910024729101814 0.947623119225231 KANK4/WASF2 2 GO:0048469 cell maturation 2/435 171/18722 0.910024729101814 0.947623119225231 APP/AKR1B1 2 GO:0048588 developmental cell growth 3/435 234/18722 0.911587922954766 0.947971735681583 NRP2/APP/HSP90AB1 3 GO:0060560 developmental growth involved in morphogenesis 3/435 234/18722 0.911587922954766 0.947971735681583 NRP2/APP/HSP90AB1 3 GO:1990138 neuron projection extension 2/435 172/18722 0.911717428389913 0.947971735681583 NRP2/HSP90AB1 2 GO:0030004 cellular monovalent inorganic cation homeostasis 1/435 103/18722 0.911796923427876 0.947971735681583 CLN3 1 GO:0045639 positive regulation of myeloid cell differentiation 1/435 103/18722 0.911796923427876 0.947971735681583 PRMT1 1 GO:1905037 autophagosome organization 1/435 103/18722 0.911796923427876 0.947971735681583 CLN3 1 GO:0000910 cytokinesis 2/435 173/18722 0.913380283917546 0.949365883689312 MYH10/RHOC 2 GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 1/435 104/18722 0.913857632290268 0.949365883689312 TGM2 1 GO:0032963 collagen metabolic process 1/435 104/18722 0.913857632290268 0.949365883689312 CTSL 1 GO:0040029 regulation of gene expression, epigenetic 1/435 105/18722 0.915870304433018 0.950957437586317 DNMT1 1 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 1/435 105/18722 0.915870304433018 0.950957437586317 WASF2 1 GO:0001824 blastocyst development 1/435 106/18722 0.917836057109155 0.95249863046969 SF3B6 1 GO:0002062 chondrocyte differentiation 1/435 106/18722 0.917836057109155 0.95249863046969 EFEMP1 1 GO:0043534 blood vessel endothelial cell migration 2/435 176/18722 0.918194448372495 0.952620721607227 EFNA1/AMOT 2 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 5/435 356/18722 0.919379927432254 0.953241073695361 HSPD1/C1QBP/CD46/CD55/PHB 5 GO:0006333 chromatin assembly or disassembly 2/435 177/18722 0.919742561254287 0.953241073695361 HMGA1/NPM1 2 GO:0071466 cellular response to xenobiotic stimulus 2/435 177/18722 0.919742561254287 0.953241073695361 GSTP1/EGFR 2 GO:0000018 regulation of DNA recombination 1/435 107/18722 0.919755981644905 0.953241073695361 PARP1 1 GO:0032886 regulation of microtubule-based process 3/435 240/18722 0.920012347627307 0.953257098602057 MET/RPS3/NPM1 3 GO:0001818 negative regulation of cytokine production 5/435 357/18722 0.920507116368669 0.953520067924299 CD24/GSTP1/HSP90AB1/C1QBP/ATP2B1 5 GO:0035725 sodium ion transmembrane transport 2/435 178/18722 0.921263118569159 0.953632794304793 FXYD3/SLC6A4 2 GO:0022037 metencephalon development 1/435 108/18722 0.921631144039988 0.953632794304793 UQCRQ 1 GO:0098659 inorganic cation import across plasma membrane 1/435 108/18722 0.921631144039988 0.953632794304793 SLC39A10 1 GO:0099587 inorganic ion import across plasma membrane 1/435 108/18722 0.921631144039988 0.953632794304793 SLC39A10 1 GO:0001558 regulation of cell growth 6/435 414/18722 0.921820934600918 0.953632794304793 EGFR/NDUFA13/GJA1/PHB/RBBP7/NPM1 6 GO:0006399 tRNA metabolic process 2/435 179/18722 0.922756561194632 0.954333102908682 TRMT112/IARS2 2 GO:0051056 regulation of small GTPase mediated signal transduction 4/435 302/18722 0.923176777313959 0.954333102908682 ADGRG1/TGM2/MET/AMOT 4 GO:0032410 negative regulation of transporter activity 1/435 109/18722 0.923462585554042 0.954333102908682 CAV1 1 GO:0032414 positive regulation of ion transmembrane transporter activity 1/435 109/18722 0.923462585554042 0.954333102908682 NDUFA4 1 GO:0007033 vacuole organization 2/435 180/18722 0.924223324455662 0.954869894222207 ANXA2/CLN3 2 GO:0030317 flagellated sperm motility 1/435 110/18722 0.925251323279502 0.955183794995301 SLIRP 1 GO:0097722 sperm motility 1/435 110/18722 0.925251323279502 0.955183794995301 SLIRP 1 GO:1904659 glucose transmembrane transport 1/435 110/18722 0.925251323279502 0.955183794995301 SLC2A1 1 GO:0006805 xenobiotic metabolic process 1/435 111/18722 0.926998350701242 0.95632161874816 GSTP1 1 GO:0015718 monocarboxylic acid transport 1/435 111/18722 0.926998350701242 0.95632161874816 MPC2 1 GO:0060401 cytosolic calcium ion transport 2/435 182/18722 0.927078526539788 0.95632161874816 ATP2B1/CAV1 2 GO:0000956 nuclear-transcribed mRNA catabolic process 1/435 112/18722 0.928704638243284 0.957749349368954 LSM7 1 GO:2001257 regulation of cation channel activity 2/435 184/18722 0.929832097157987 0.958662222108951 APP/CAV1 2 GO:0071347 cellular response to interleukin-1 1/435 113/18722 0.930371133802885 0.958968110564735 CD47 1 GO:0043433 negative regulation of DNA-binding transcription factor activity 2/435 185/18722 0.931171800602558 0.959396229518305 BMP7/PRDX2 2 GO:1901988 negative regulation of cell cycle phase transition 3/435 249/18722 0.93128267226968 0.959396229518305 CTDSPL/CCND1/LCMT1 3 GO:0007041 lysosomal transport 1/435 114/18722 0.931998763272268 0.959396229518305 CLN3 1 GO:0008645 hexose transmembrane transport 1/435 114/18722 0.931998763272268 0.959396229518305 SLC2A1 1 GO:0051261 protein depolymerization 1/435 114/18722 0.931998763272268 0.959396229518305 DSTN 1 GO:0031345 negative regulation of cell projection organization 2/435 186/18722 0.93248732125476 0.959649500703533 EFNA1/TACSTD2 2 GO:0000077 DNA damage checkpoint signaling 1/435 115/18722 0.933588431048309 0.960351824828161 CCND1 1 GO:0002695 negative regulation of leukocyte activation 2/435 187/18722 0.933779056224322 0.960351824828161 PRDX2/LGALS3 2 GO:0019932 second-messenger-mediated signaling 4/435 312/18722 0.934140554400705 0.960351824828161 EGFR/BCAP31/NUDT4/FIS1 4 GO:0070588 calcium ion transmembrane transport 4/435 312/18722 0.934140554400705 0.960351824828161 ANXA2/STOML2/ATP2B1/TSPAN13 4 GO:0015749 monosaccharide transmembrane transport 1/435 116/18722 0.935141020530438 0.961130654088037 SLC2A1 1 GO:0046578 regulation of Ras protein signal transduction 2/435 189/18722 0.936292730864777 0.961939608216989 ADGRG1/MET 2 GO:0051225 spindle assembly 1/435 117/18722 0.93665739460704 0.961939608216989 RPS3 1 GO:0072676 lymphocyte migration 1/435 117/18722 0.93665739460704 0.961939608216989 APP 1 GO:0051216 cartilage development 2/435 190/18722 0.93751543816681 0.962461403549082 EFEMP1/BMP7 2 GO:0006338 chromatin remodeling 3/435 255/18722 0.937965533724553 0.962461403549082 HMGA1/ZNHIT1/NPM1 3 GO:0034219 carbohydrate transmembrane transport 1/435 118/18722 0.938138396130606 0.962461403549082 SLC2A1 1 GO:1903313 positive regulation of mRNA metabolic process 1/435 118/18722 0.938138396130606 0.962461403549082 PRDX6 1 GO:0002761 regulation of myeloid leukocyte differentiation 1/435 120/18722 0.940997555523435 0.964976109047859 FBN1 1 GO:0045165 cell fate commitment 3/435 258/18722 0.941077281985264 0.964976109047859 LMO4/CTSL/NR2F2 3 GO:0030168 platelet activation 1/435 123/18722 0.94504097037096 0.968538492555786 GNAS 1 GO:0031570 DNA integrity checkpoint signaling 1/435 123/18722 0.94504097037096 0.968538492555786 CCND1 1 GO:0042692 muscle cell differentiation 5/435 384/18722 0.946111113555847 0.969384173055538 KRT8/DNMT1/CSRP2/CALR/LMNA 5 GO:0060294 cilium movement involved in cell motility 1/435 125/18722 0.947581776953997 0.970639681958832 SLIRP 1 GO:0006403 RNA localization 2/435 201/18722 0.949575731778892 0.972178828111016 NHP2/NPM1 2 GO:0009952 anterior/posterior pattern specification 2/435 201/18722 0.949575731778892 0.972178828111016 WLS/NR2F2 2 GO:0008033 tRNA processing 1/435 127/18722 0.950005377246691 0.972367117890625 TRMT112 1 GO:0009913 epidermal cell differentiation 2/435 202/18722 0.950554787033081 0.972677861983424 SOD1/DSP 2 GO:0006639 acylglycerol metabolic process 1/435 128/18722 0.951174920720619 0.973060796611036 CAV1 1 GO:0006334 nucleosome assembly 1/435 129/18722 0.952317166040966 0.973725846517856 NPM1 1 GO:0006638 neutral lipid metabolic process 1/435 129/18722 0.952317166040966 0.973725846517856 CAV1 1 GO:0007098 centrosome cycle 1/435 130/18722 0.953432748936259 0.97461466999245 NPM1 1 GO:0019827 stem cell population maintenance 1/435 131/18722 0.954522290363363 0.975030831870639 BMP7 1 GO:0050853 B cell receptor signaling pathway 1/435 131/18722 0.954522290363363 0.975030831870639 SLC39A10 1 GO:0034249 negative regulation of cellular amide metabolic process 3/435 273/18722 0.954579085839488 0.975030831870639 RPS3/CALR/ORMDL1 3 GO:0060271 cilium assembly 4/435 337/18722 0.955624381544853 0.97584662652206 GALNT11/DYNLL2/LAMA5/RAB17 4 GO:0006836 neurotransmitter transport 2/435 208/18722 0.956059058884701 0.976038621260775 SLC6A4/PARK7 2 GO:0098727 maintenance of cell number 1/435 134/18722 0.957640660965583 0.977018917431256 BMP7 1 GO:0045637 regulation of myeloid cell differentiation 2/435 210/18722 0.957760015343908 0.977018917431256 FBN1/PRMT1 2 GO:0050866 negative regulation of cell activation 2/435 210/18722 0.957760015343908 0.977018917431256 PRDX2/LGALS3 2 GO:0043624 cellular protein complex disassembly 1/435 136/18722 0.959600117440608 0.978391565244135 DSTN 1 GO:1903305 regulation of regulated secretory pathway 1/435 136/18722 0.959600117440608 0.978391565244135 VAMP8 1 GO:0010977 negative regulation of neuron projection development 1/435 137/18722 0.960545665106235 0.979103347971502 EFNA1 1 GO:0000724 double-strand break repair via homologous recombination 1/435 138/18722 0.961469132186073 0.979287865137784 PARP1 1 GO:0001539 cilium or flagellum-dependent cell motility 1/435 138/18722 0.961469132186073 0.979287865137784 SLIRP 1 GO:0060285 cilium-dependent cell motility 1/435 138/18722 0.961469132186073 0.979287865137784 SLIRP 1 GO:0016579 protein deubiquitination 1/435 139/18722 0.962371033149216 0.97933906772553 PARK7 1 GO:0030216 keratinocyte differentiation 1/435 139/18722 0.962371033149216 0.97933906772553 DSP 1 GO:0002377 immunoglobulin production 2/435 216/18722 0.96249309988029 0.97933906772553 HSPD1/PHB 2 GO:0006417 regulation of translation 6/435 468/18722 0.96290337711376 0.97933906772553 RPS14/APP/RPS3/C1QBP/CALR/NPM1 6 GO:0000725 recombinational repair 1/435 140/18722 0.963251870504869 0.97933906772553 PARP1 1 GO:0007292 female gamete generation 1/435 140/18722 0.963251870504869 0.97933906772553 LGR5 1 GO:0050768 negative regulation of neurogenesis 1/435 140/18722 0.963251870504869 0.97933906772553 BMP7 1 GO:0042742 defense response to bacterium 4/435 350/18722 0.964047398403532 0.979517136323102 COLEC12/ANXA3/RPS19/ROMO1 4 GO:0030183 B cell differentiation 1/435 141/18722 0.964112135079747 0.979517136323102 BAD 1 GO:0140014 mitotic nuclear division 3/435 287/18722 0.964522026505109 0.979517136323102 BMP7/AURKAIP1/LCMT1 3 GO:0034764 positive regulation of transmembrane transport 2/435 219/18722 0.964664715757171 0.979517136323102 NDUFA4/KCNN4 2 GO:0071805 potassium ion transmembrane transport 2/435 219/18722 0.964664715757171 0.979517136323102 KCNN4/CAV1 2 GO:0031023 microtubule organizing center organization 1/435 143/18722 0.965772852401241 0.980390758581762 NPM1 1 GO:0071103 DNA conformation change 3/435 290/18722 0.966367983616571 0.980701084938907 HMGA1/SSBP1/NPM1 3 GO:0010324 membrane invagination 1/435 144/18722 0.966574230796496 0.980701084938907 SNX3 1 GO:0051961 negative regulation of nervous system development 1/435 145/18722 0.967356888219444 0.981243580283092 BMP7 1 GO:0048813 dendrite morphogenesis 1/435 146/18722 0.968121261025847 0.981767255222777 EFNA1 1 GO:1902850 microtubule cytoskeleton organization involved in mitosis 1/435 147/18722 0.968867775423659 0.982272556328829 GJA1 1 GO:0046777 protein autophosphorylation 2/435 227/18722 0.969881489730858 0.983048425938782 EGFR/CAV1 2 GO:0045834 positive regulation of lipid metabolic process 1/435 149/18722 0.970308884493608 0.983229771047684 STOML2 1 GO:0031497 chromatin assembly 1/435 151/18722 0.971683430949039 0.983783155536303 NPM1 1 GO:0043535 regulation of blood vessel endothelial cell migration 1/435 151/18722 0.971683430949039 0.983783155536303 EFNA1 1 GO:1904064 positive regulation of cation transmembrane transport 1/435 151/18722 0.971683430949039 0.983783155536303 KCNN4 1 GO:0048285 organelle fission 6/435 488/18722 0.972252945121531 0.983783155536303 BMP7/AURKAIP1/CALR/FIS1/BNIP3/LCMT1 6 GO:0008643 carbohydrate transport 1/435 152/18722 0.972346707430498 0.983783155536303 SLC2A1 1 GO:0016573 histone acetylation 1/435 152/18722 0.972346707430498 0.983783155536303 PARK7 1 GO:0006402 mRNA catabolic process 2/435 232/18722 0.972756723379596 0.983946409614791 LSM7/NPM1 2 GO:0044782 cilium organization 4/435 368/18722 0.97328095098305 0.984225076166606 GALNT11/DYNLL2/LAMA5/RAB17 4 GO:0050770 regulation of axonogenesis 1/435 154/18722 0.973627117502301 0.984323583024171 EFNA1 1 GO:0051147 regulation of muscle cell differentiation 1/435 155/18722 0.974244965621996 0.984696635751274 DNMT1 1 GO:0007034 vacuolar transport 1/435 157/18722 0.975437672444962 0.985225566413749 CLN3 1 GO:0070646 protein modification by small protein removal 1/435 157/18722 0.975437672444962 0.985225566413749 PARK7 1 GO:0002440 production of molecular mediator of immune response 3/435 308/18722 0.975676323742988 0.985225566413749 HSPD1/CD55/PHB 3 GO:0018393 internal peptidyl-lysine acetylation 1/435 158/18722 0.976013196952716 0.985225566413749 PARK7 1 GO:0043488 regulation of mRNA stability 1/435 158/18722 0.976013196952716 0.985225566413749 NPM1 1 GO:1903169 regulation of calcium ion transmembrane transport 1/435 159/18722 0.976575266513455 0.985541527567902 TSPAN13 1 GO:0006475 internal protein amino acid acetylation 1/435 160/18722 0.977124194976885 0.98559277071719 PARK7 1 GO:0060402 calcium ion transport into cytosol 1/435 160/18722 0.977124194976885 0.98559277071719 CAV1 1 GO:0050657 nucleic acid transport 1/435 163/18722 0.97869516372907 0.986526800921022 NPM1 1 GO:0050658 RNA transport 1/435 163/18722 0.97869516372907 0.986526800921022 NPM1 1 GO:0007018 microtubule-based movement 4/435 382/18722 0.978874888558936 0.986526800921022 SOD1/SLIRP/APP/CLN3 4 GO:0017148 negative regulation of translation 2/435 245/18722 0.979047446857936 0.986526800921022 RPS3/CALR 2 GO:0007286 spermatid development 1/435 165/18722 0.979682203659527 0.986641338434206 SLIRP 1 GO:0030307 positive regulation of cell growth 1/435 166/18722 0.980158478995417 0.986641338434206 EGFR 1 GO:0051236 establishment of RNA localization 1/435 166/18722 0.980158478995417 0.986641338434206 NPM1 1 GO:0061013 regulation of mRNA catabolic process 1/435 166/18722 0.980158478995417 0.986641338434206 NPM1 1 GO:0000070 mitotic sister chromatid segregation 1/435 168/18722 0.981077871289919 0.987315650227419 LCMT1 1 GO:0018394 peptidyl-lysine acetylation 1/435 169/18722 0.981521502096693 0.987510954435956 PARK7 1 GO:0061448 connective tissue development 2/435 252/18722 0.981827002683061 0.987567221559957 EFEMP1/BMP7 2 GO:0048515 spermatid differentiation 1/435 172/18722 0.982791092071013 0.988285730959339 SLIRP 1 GO:0048639 positive regulation of developmental growth 1/435 174/18722 0.983588752406911 0.988836558250546 PPIB 1 GO:0003341 cilium movement 1/435 175/18722 0.983973639872028 0.98897223595977 SLIRP 1 GO:0045927 positive regulation of growth 2/435 259/18722 0.984247756586178 0.988996539566152 EGFR/PPIB 2 GO:0007051 spindle organization 1/435 184/18722 0.987056572861797 0.99156711317952 RPS3 1 GO:0140013 meiotic nuclear division 1/435 185/18722 0.987360294450162 0.991620478461749 CALR 1 GO:1902115 regulation of organelle assembly 1/435 186/18722 0.987656905116084 0.991666676869917 NPM1 1 GO:0007059 chromosome segregation 3/435 346/18722 0.987939976223654 0.991699260760274 RPS3/BEX4/LCMT1 3 GO:0006887 exocytosis 3/435 352/18722 0.989225735580312 0.992606475465502 VAMP8/ANXA3/S100A13 3 GO:0007281 germ cell development 2/435 278/18722 0.98934544837906 0.992606475465502 SLIRP/LGR5 2 GO:0006323 DNA packaging 1/435 199/18722 0.990936305735201 0.993317218746055 NPM1 1 GO:0099003 vesicle-mediated transport in synapse 1/435 200/18722 0.991149160402652 0.993317218746055 NSG1 1 GO:0006473 protein acetylation 1/435 201/18722 0.991357027545771 0.993317218746055 PARK7 1 GO:0000819 sister chromatid segregation 1/435 202/18722 0.991560023767227 0.993317218746055 LCMT1 1 GO:0017157 regulation of exocytosis 1/435 202/18722 0.991560023767227 0.993317218746055 VAMP8 1 GO:1903046 meiotic cell cycle process 1/435 202/18722 0.991560023767227 0.993317218746055 CALR 1 GO:0000280 nuclear division 4/435 439/18722 0.992142231364951 0.993648901420175 BMP7/AURKAIP1/CALR/LCMT1 4 GO:0006310 DNA recombination 2/435 305/18722 0.993928683078421 0.99518618394264 PARP1/HSPD1 2 GO:0000209 protein polyubiquitination 1/435 236/18722 0.996241102761727 0.997249188876335 SKP2 1 GO:0043543 protein acylation 1/435 243/18722 0.996818317907023 0.997574629225617 PARK7 1 GO:0006302 double-strand break repair 1/435 251/18722 0.997370484478276 0.997874843762462 PARP1 1 GO:0051321 meiotic cell cycle 1/435 261/18722 0.997928197300513 0.998180454175463 CALR 1 GO:0098813 nuclear chromosome segregation 1/435 281/18722 0.998714348255936 0.998714348255936 LCMT1 1