ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	Count
GO:0043274	phospholipase binding	5/202	24/18367	5.4904582870456e-06	0.00258600585319848	ARHGAP6/BANK1/BTK/FYN/SNCA	5
GO:0016004	phospholipase activator activity	4/202	16/18367	2.33034755621649e-05	0.0045345798055989	ARHGAP6/CCL5/BTK/FYN	4
GO:0047485	protein N-terminus binding	8/202	110/18367	2.92586864848827e-05	0.0045345798055989	NFE2/EPB41/PDCD10/GADD45A/SNCA/ZMYND8/TBL1XR1/CALM3	8
GO:0060229	lipase activator activity	4/202	18/18367	3.85102318946828e-05	0.0045345798055989	ARHGAP6/CCL5/BTK/FYN	4
GO:0015662	P-type ion transporter activity	4/202	21/18367	7.33983397978291e-05	0.00576176967412958	ABCC4/ATP2A3/ATP1B1/ATP2C1	4
GO:0140358	P-type transmembrane transporter activity	4/202	21/18367	7.33983397978291e-05	0.00576176967412958	ABCC4/ATP2A3/ATP1B1/ATP2C1	4
GO:0003924	GTPase activity	13/202	337/18367	9.55612166152566e-05	0.00590561619364165	TUBB1/GNG11/DNM3/RGS18/TUBA4A/RAB27B/RGS10/RAB32/RAP1B/RAB30/RAB11A/GNA13/RAP2B	13
GO:0003779	actin binding	15/202	440/18367	0.000111524093125388	0.00590561619364165	NEXN/MYLK/TMSB4X/EPB41/VCL/PSTPIP2/SNCA/CAPZA2/TLN1/MTSS1/PDLIM1/CORO1C/DAAM1/TPM1/FLNA	15
GO:0044325	transmembrane transporter binding	8/202	133/18367	0.000112846169305254	0.00590561619364165	ATP2A3/TRAPPC2/FYN/CRBN/YWHAZ/YWHAE/FLNA/CALM3	8
GO:0035256	G protein-coupled glutamate receptor binding	3/202	12/18367	0.000267993639208348	0.0126225004067132	DNM3/FYN/CALM3	3
GO:0003925	G protein activity	4/202	40/18367	0.000952015997535909	0.0407635940763103	RAB27B/RAP1B/RAB11A/RAP2B	4
GO:0019207	kinase regulator activity	9/202	233/18367	0.00113250980574376	0.0444510098754425	PRKAR2B/TAL1/CCL5/CDKN2D/MOB1B/SNCA/HMGB1/SOCS2/CALM3	9
GO:0001664	G protein-coupled receptor binding	10/202	295/18367	0.00163000065294448	0.0588779903192185	PPBP/PF4/DNM3/P2RY1/CCL5/FYN/STAT3/GNA13/FLNA/CALM3	10
GO:0035254	glutamate receptor binding	4/202	47/18367	0.00175008888422305	0.0588779903192185	DNM3/MYL12A/FYN/CALM3	4
GO:0019887	protein kinase regulator activity	8/202	204/18367	0.00192610620856868	0.0591889258929031	PRKAR2B/TAL1/CCL5/CDKN2D/MOB1B/SNCA/HMGB1/CALM3	8
GO:0005543	phospholipid binding	13/202	466/18367	0.00201066414922813	0.0591889258929031	NRGN/THBS1/BTK/LAPTM4B/DAPP1/EPB41/STAM/BIN2/SNCA/PLEKHF2/TLN1/HMGB1/MTSS1	13
GO:0008198	ferrous iron binding	3/202	26/18367	0.00282782870722158	0.0783474894765507	EGLN3/FTH1/SNCA	3
GO:0023026	MHC class II protein complex binding	3/202	27/18367	0.00315575807501517	0.0825756696295638	ATP1B1/B2M/YWHAE	3
GO:0005125	cytokine activity	8/202	235/18367	0.00456788564658101	0.105308183627443	PPBP/PF4/CMTM5/TNFSF4/CCL5/TGFB1/HMGB1/TIMP1	8
GO:0019001	guanyl nucleotide binding	11/202	398/18367	0.00469526933370766	0.105308183627443	TUBB1/PDE5A/DNM3/TUBA4A/RAB27B/RAB32/RAP1B/RAB30/RAB11A/GNA13/RAP2B	11
GO:0032561	guanyl ribonucleotide binding	11/202	398/18367	0.00469526933370766	0.105308183627443	TUBB1/PDE5A/DNM3/TUBA4A/RAB27B/RAB32/RAP1B/RAB30/RAB11A/GNA13/RAP2B	11
GO:0030295	protein kinase activator activity	5/202	101/18367	0.00517085082625887	0.10697214383857	TAL1/CCL5/MOB1B/HMGB1/CALM3	5
GO:0005178	integrin binding	6/202	144/18367	0.00522369279891107	0.10697214383857	CD226/THBS1/FERMT3/ICAM2/TLN1/HMGB1	6
GO:0005200	structural constituent of cytoskeleton	5/202	103/18367	0.00561539814061437	0.110202188509557	TUBB1/TUBA4A/EPB41/TLN1/TPM1	5
GO:0042608	T cell receptor binding	2/202	11/18367	0.00620121135673855	0.11485864291219	FYN/HLA-E	2
GO:0140677	molecular function activator activity	6/202	150/18367	0.00635096124185991	0.11485864291219	ARHGAP6/CCL5/BTK/ATP1B1/FYN/CALM3	6
GO:0019209	kinase activator activity	5/202	107/18367	0.00658425341534847	0.11485864291219	TAL1/CCL5/MOB1B/HMGB1/CALM3	5
GO:0023023	MHC protein complex binding	3/202	36/18367	0.00716545618240654	0.119922697794684	ATP1B1/B2M/YWHAE	3
GO:0008047	enzyme activator activity	5/202	110/18367	0.00738377544808031	0.119922697794684	ARHGAP6/CCL5/BTK/FYN/CALM3	5
GO:0042379	chemokine receptor binding	4/202	72/18367	0.00816156627257955	0.128136590479499	PPBP/PF4/CCL5/STAT3	4
GO:0044389	ubiquitin-like protein ligase binding	9/202	316/18367	0.00845103620113621	0.128401227443069	PRKAR2B/LAPTM4B/YOD1/STAM/VCL/CLU/YWHAZ/BLZF1/YWHAE	9
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	3/202	39/18367	0.00895367340877737	0.129556990355029	NRGN/BTK/DAPP1	3
GO:0005525	GTP binding	10/202	377/18367	0.00907724136245428	0.129556990355029	TUBB1/DNM3/TUBA4A/RAB27B/RAB32/RAP1B/RAB30/RAB11A/GNA13/RAP2B	10
GO:0019992	diacylglycerol binding	2/202	14/18367	0.0100402707226612	0.135178227892653	RASGRP2/DGKD	2
GO:0051015	actin filament binding	7/202	217/18367	0.0103207855949808	0.135178227892653	NEXN/PSTPIP2/CAPZA2/TLN1/CORO1C/TPM1/FLNA	7
GO:0035091	phosphatidylinositol binding	8/202	271/18367	0.0104226314713706	0.135178227892653	NRGN/BTK/LAPTM4B/DAPP1/EPB41/STAM/PLEKHF2/TLN1	8
GO:0046982	protein heterodimerization activity	9/202	328/18367	0.0106190964586585	0.135178227892653	P2RY1/ATP1B1/MAX/GADD45A/DGKD/YWHAE/PDGFA/TPM1/BCL2L1	9
GO:0008307	structural constituent of muscle	3/202	42/18367	0.0109804148009841	0.136099351875355	NEXN/MYL9/TPM1	3
GO:0050998	nitric-oxide synthase binding	2/202	15/18367	0.0115017088798683	0.138905253395332	DNM3/CALM3	2
GO:0035591	signaling adaptor activity	4/202	81/18367	0.0122324731316097	0.144037371124704	LAT/BANK1/SOCS2/STAT3	4
GO:0008191	metalloendopeptidase inhibitor activity	2/202	16/18367	0.0130504711068125	0.145145456863093	LXN/TIMP1	2
GO:0004715	non-membrane spanning protein tyrosine kinase activity	3/202	45/18367	0.013251071433361	0.145145456863093	BTK/FYN/CLK1	3
GO:0048156	tau protein binding	3/202	45/18367	0.013251071433361	0.145145456863093	CLU/FYN/SNCA	3
GO:0031489	myosin V binding	2/202	17/18367	0.0146844795383249	0.155978542091378	RAB27B/RAB11A	2
GO:0019829	ATPase-coupled cation transmembrane transporter activity	3/202	47/18367	0.014902408480068	0.155978542091378	ATP2A3/ATP1B1/ATP2C1	3
GO:0008301	DNA binding, bending	2/202	18/18367	0.0164016910558424	0.156233759245042	HHEX/HMGB1	2
GO:0045236	CXCR chemokine receptor binding	2/202	18/18367	0.0164016910558424	0.156233759245042	PPBP/PF4	2
GO:0140597	protein carrier activity	2/202	18/18367	0.0164016910558424	0.156233759245042	CLU/EMC3	2
GO:0008009	chemokine activity	3/202	49/18367	0.0166648796969544	0.156233759245042	PPBP/PF4/CCL5	3
GO:0098632	cell-cell adhesion mediator activity	3/202	49/18367	0.0166648796969544	0.156233759245042	NEXN/ESAM/PDLIM1	3
GO:0030674	protein-macromolecule adaptor activity	8/202	296/18367	0.0169384111978562	0.156233759245042	LAT/BANK1/ATP1B1/SOCS2/STAT3/BET1/ANKRD9/TJP2	8
GO:0031625	ubiquitin protein ligase binding	8/202	297/18367	0.017248737751045	0.156233759245042	PRKAR2B/LAPTM4B/YOD1/VCL/CLU/YWHAZ/BLZF1/YWHAE	8
GO:0042393	histone binding	7/202	244/18367	0.0185697633491156	0.165025632781764	NAP1L1/MBTD1/UIMC1/SNCA/ZMYND8/BRD3/TBL1XR1	7
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/202	20/18367	0.0200777215741556	0.168867979668345	TBPL1/GTF2B	2
GO:0030296	protein tyrosine kinase activator activity	2/202	20/18367	0.0200777215741556	0.168867979668345	TAL1/CCL5	2
GO:0031681	G-protein beta-subunit binding	2/202	20/18367	0.0200777215741556	0.168867979668345	GNG11/F2R	2
GO:0070577	lysine-acetylated histone binding	2/202	21/18367	0.0220326235444884	0.178920098094035	ZMYND8/BRD3	2
GO:0140033	acetylation-dependent protein binding	2/202	21/18367	0.0220326235444884	0.178920098094035	ZMYND8/BRD3	2
GO:0050840	extracellular matrix binding	3/202	56/18367	0.0237164276514396	0.18579709617924	ITGA2B/THBS1/SPARC	3
GO:0005355	glucose transmembrane transporter activity	2/202	22/18367	0.0240628935603687	0.18579709617924	PPBP/SLC2A3	2
GO:0015149	hexose transmembrane transporter activity	2/202	22/18367	0.0240628935603687	0.18579709617924	PPBP/SLC2A3	2
GO:0005506	iron ion binding	5/202	151/18367	0.025835109620102	0.195626895193677	ALOX12/FAXDC2/EGLN3/FTH1/SNCA	5
GO:0017025	TBP-class protein binding	2/202	23/18367	0.0261666547711288	0.195626895193677	HHEX/GTF2B	2
GO:0098631	cell adhesion mediator activity	3/202	59/18367	0.0271602815577634	0.196464853392889	NEXN/ESAM/PDLIM1	3
GO:0001965	G-protein alpha-subunit binding	2/202	24/18367	0.0283420621334189	0.196464853392889	F2R/RGS10	2
GO:0015145	monosaccharide transmembrane transporter activity	2/202	24/18367	0.0283420621334189	0.196464853392889	PPBP/SLC2A3	2
GO:0050431	transforming growth factor beta binding	2/202	24/18367	0.0283420621334189	0.196464853392889	THBS1/LTBP1	2
GO:0001786	phosphatidylserine binding	3/202	60/18367	0.0283643525068289	0.196464853392889	THBS1/TLN1/HMGB1	3
GO:0005126	cytokine receptor binding	7/202	271/18367	0.0306218130595468	0.204768695355083	PPBP/PF4/TNFSF4/CCL5/TGFB1/SOCS2/STAT3	7
GO:0140297	DNA-binding transcription factor binding	9/202	394/18367	0.0306326351967099	0.204768695355083	TAL1/GATA1/HHEX/YWHAZ/EIF4E/ZMYND8/HMGB1/GTF2B/STAT3	9
GO:0045296	cadherin binding	8/202	332/18367	0.0308674678773055	0.204768695355083	VCL/TAGLN2/YWHAZ/TLN1/PDLIM1/YWHAE/TJP2/FLNA	8
GO:0140030	modification-dependent protein binding	5/202	160/18367	0.0320488646029306	0.208680396654627	MBTD1/UIMC1/ZMYND8/BRD3/ZFAND2B	5
GO:0042626	ATPase-coupled transmembrane transporter activity	4/202	109/18367	0.0323432461906322	0.208680396654627	ABCC4/ATP2A3/ATP1B1/ATP2C1	4
GO:0051119	sugar transmembrane transporter activity	2/202	27/18367	0.0352801780451907	0.224553565666011	PPBP/SLC2A3	2
GO:0097110	scaffold protein binding	3/202	67/18367	0.0375721211890964	0.233791630431628	P2RY1/FYN/YWHAE	3
GO:0003785	actin monomer binding	2/202	28/18367	0.03772433951763	0.233791630431628	TMSB4X/MTSS1	2
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	2/202	29/18367	0.0402313829134292	0.244259569586446	DAPP1/PLEK	2
GO:0005518	collagen binding	3/202	69/18367	0.0404506293582649	0.244259569586446	THBS1/SPARC/PDGFA	3
GO:0004860	protein kinase inhibitor activity	3/202	70/18367	0.0419305941492195	0.249991263851676	PRKAR2B/CDKN2D/SNCA	3
GO:0030546	signaling receptor activator activity	10/202	495/18367	0.0475468747999711	0.276388283278377	PPBP/PF4/CMTM5/TAL1/TNFSF4/CCL5/TGFB1/HMGB1/PDGFA/TIMP1	10
GO:0017022	myosin binding	3/202	74/18367	0.0481185546259594	0.276388283278377	RAB27B/MYL9/RAB11A	3
GO:0019210	kinase inhibitor activity	3/202	74/18367	0.0481185546259594	0.276388283278377	PRKAR2B/CDKN2D/SNCA	3
GO:0019003	GDP binding	3/202	75/18367	0.0497317940568278	0.278522714715339	RAB27B/RAP1B/RAP2B	3
GO:0015399	primary active transmembrane transporter activity	5/202	181/18367	0.0499353473685694	0.278522714715339	ABCC4/ATP2A3/ATP1B1/ATP2C1/UQCRH	5
GO:0031369	translation initiation factor binding	2/202	33/18367	0.0508555275276415	0.278522714715339	HHEX/EIF4E	2
GO:0051427	hormone receptor binding	2/202	33/18367	0.0508555275276415	0.278522714715339	FYN/SOCS2	2
GO:0060090	molecular adaptor activity	8/202	369/18367	0.0518310334170738	0.280602491257951	LAT/BANK1/ATP1B1/SOCS2/STAT3/BET1/ANKRD9/TJP2	8
GO:0030291	protein serine/threonine kinase inhibitor activity	2/202	34/18367	0.0536525908216275	0.283936744685242	PRKAR2B/CDKN2D	2
GO:0043548	phosphatidylinositol 3-kinase binding	2/202	34/18367	0.0536525908216275	0.283936744685242	FYN/CALM3	2
GO:0097718	disordered domain specific binding	2/202	36/18367	0.059405181958547	0.310887118916396	FYN/CALM3	2
GO:0002020	protease binding	4/202	135/18367	0.0620124434208721	0.315811779882136	BANK1/MBP/RIOK3/TIMP1	4
GO:0030551	cyclic nucleotide binding	2/202	37/18367	0.0623577399767276	0.315811779882136	PRKAR2B/PDE5A	2
GO:0042056	chemoattractant activity	2/202	37/18367	0.0623577399767276	0.315811779882136	CCL5/HMGB1	2
GO:0016251	RNA polymerase II general transcription initiation factor activity	2/202	38/18367	0.0653592030369442	0.3242765179612	TBPL1/GTF2B	2
GO:0008135	translation factor activity, RNA binding	3/202	84/18367	0.0654060917331507	0.3242765179612	EIF1B/EIF4E/CPEB4	3
GO:0015144	carbohydrate transmembrane transporter activity	2/202	40/18367	0.0715031871182174	0.343653072782453	PPBP/SLC2A3	2
GO:0043014	alpha-tubulin binding	2/202	40/18367	0.0715031871182174	0.343653072782453	FYN/SNCA	2
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/202	40/18367	0.0715031871182174	0.343653072782453	ATP2A3/SNCA	2
GO:0051219	phosphoprotein binding	3/202	88/18367	0.0730154313178618	0.345153834753199	EPB41/SNCA/YWHAE	3
GO:0019199	transmembrane receptor protein kinase activity	4/202	143/18367	0.0732810689497237	0.345153834753199	BTK/FYN/CLK1/LTBP1	4
GO:0022853	active ion transmembrane transporter activity	6/202	267/18367	0.0750876929110075	0.350161419416678	ABCC4/ATP2A3/ATP1B1/ATP2C1/CLCN3/UQCRH	6
GO:0001046	core promoter sequence-specific DNA binding	2/202	42/18367	0.0778260681673781	0.355884253464418	TBPL1/GTF2B	2
GO:0019894	kinesin binding	2/202	42/18367	0.0778260681673781	0.355884253464418	SNCA/KIFAP3	2
GO:0051213	dioxygenase activity	3/202	92/18367	0.0810004159976336	0.366838422450821	ALOX12/PTGS1/EGLN3	3
GO:0072341	modified amino acid binding	3/202	93/18367	0.0830535746880067	0.37255460645763	THBS1/TLN1/HMGB1	3
GO:0008375	acetylglucosaminyltransferase activity	2/202	44/18367	0.0843171691434606	0.374654591194056	B3GNT2/MGAT4B	2
GO:0140223	general transcription initiation factor activity	2/202	45/18367	0.0876225690369535	0.385703084265468	TBPL1/GTF2B	2
GO:0048018	receptor ligand activity	9/202	487/18367	0.0898471438753019	0.391833377456178	PPBP/PF4/CMTM5/TNFSF4/CCL5/TGFB1/HMGB1/PDGFA/TIMP1	9
GO:0140296	general transcription initiation factor binding	2/202	46/18367	0.0909661904150591	0.392963523470889	HHEX/GTF2B	2
GO:0048020	CCR chemokine receptor binding	2/202	48/18367	0.0977631984925738	0.392963523470889	CCL5/STAT3	2
GO:0070888	E-box binding	2/202	48/18367	0.0977631984925738	0.392963523470889	TAL1/MAX	2
GO:0008083	growth factor activity	4/202	162/18367	0.103844983764825	0.392963523470889	PPBP/TGFB1/PDGFA/TIMP1	4
GO:0005384	manganese ion transmembrane transporter activity	1/202	10/18367	0.104717850364414	0.392963523470889	ATP2C1	1
GO:0008190	eukaryotic initiation factor 4E binding	1/202	10/18367	0.104717850364414	0.392963523470889	HHEX	1
GO:0016803	ether hydrolase activity	1/202	10/18367	0.104717850364414	0.392963523470889	ALOX12	1
GO:0034713	type I transforming growth factor beta receptor binding	1/202	10/18367	0.104717850364414	0.392963523470889	TGFB1	1
GO:0035612	AP-2 adaptor complex binding	1/202	10/18367	0.104717850364414	0.392963523470889	BMP2K	1
GO:0045294	alpha-catenin binding	1/202	10/18367	0.104717850364414	0.392963523470889	VCL	1
GO:0050786	RAGE receptor binding	1/202	10/18367	0.104717850364414	0.392963523470889	HMGB1	1
GO:0003743	translation initiation factor activity	2/202	51/18367	0.108215327814415	0.392963523470889	EIF1B/EIF4E	2
GO:0004601	peroxidase activity	2/202	51/18367	0.108215327814415	0.392963523470889	PTGS1/GPX1	2
GO:0051018	protein kinase A binding	2/202	51/18367	0.108215327814415	0.392963523470889	PRKAR2B/C2orf88	2
GO:0031593	polyubiquitin modification-dependent protein binding	2/202	52/18367	0.111763206360967	0.392963523470889	UIMC1/ZFAND2B	2
GO:0019208	phosphatase regulator activity	3/202	107/18367	0.114019871924652	0.392963523470889	BMP2K/ZEB2/CALM3	3
GO:0002162	dystroglycan binding	1/202	11/18367	0.114569514265181	0.392963523470889	VCL	1
GO:0004143	diacylglycerol kinase activity	1/202	11/18367	0.114569514265181	0.392963523470889	DGKD	1
GO:0005247	voltage-gated chloride channel activity	1/202	11/18367	0.114569514265181	0.392963523470889	CLCN3	1
GO:0005536	glucose binding	1/202	11/18367	0.114569514265181	0.392963523470889	SLC2A3	1
GO:0008199	ferric iron binding	1/202	11/18367	0.114569514265181	0.392963523470889	FTH1	1
GO:0008603	cAMP-dependent protein kinase regulator activity	1/202	11/18367	0.114569514265181	0.392963523470889	PRKAR2B	1
GO:0016801	hydrolase activity, acting on ether bonds	1/202	11/18367	0.114569514265181	0.392963523470889	ALOX12	1
GO:0035673	oligopeptide transmembrane transporter activity	1/202	11/18367	0.114569514265181	0.392963523470889	ABCC4	1
GO:0048407	platelet-derived growth factor binding	1/202	11/18367	0.114569514265181	0.392963523470889	PDGFA	1
GO:0051400	BH domain binding	1/202	11/18367	0.114569514265181	0.392963523470889	BCL2L1	1
GO:0061665	SUMO ligase activity	1/202	11/18367	0.114569514265181	0.392963523470889	KIAA1586	1
GO:0070513	death domain binding	1/202	11/18367	0.114569514265181	0.392963523470889	BCL2L1	1
GO:0099186	structural constituent of postsynapse	1/202	11/18367	0.114569514265181	0.392963523470889	DNM3	1
GO:0090079	translation regulator activity, nucleic acid binding	3/202	108/18367	0.116379946539627	0.392963523470889	EIF1B/EIF4E/CPEB4	3
GO:0015459	potassium channel regulator activity	2/202	54/18367	0.118948072743099	0.392963523470889	YWHAE/FLNA	2
GO:0005080	protein kinase C binding	2/202	55/18367	0.122582916844661	0.392963523470889	PLEK/FLNA	2
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	2/202	55/18367	0.122582916844661	0.392963523470889	PTGS1/GPX1	2
GO:1901981	phosphatidylinositol phosphate binding	4/202	173/18367	0.123807984141296	0.392963523470889	NRGN/BTK/LAPTM4B/DAPP1	4
GO:0000340	RNA 7-methylguanosine cap binding	1/202	12/18367	0.124313301480175	0.392963523470889	EIF4E	1
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/202	12/18367	0.124313301480175	0.392963523470889	CDKN2D	1
GO:0005024	transforming growth factor beta-activated receptor activity	1/202	12/18367	0.124313301480175	0.392963523470889	LTBP1	1
GO:0017166	vinculin binding	1/202	12/18367	0.124313301480175	0.392963523470889	TLN1	1
GO:0031543	peptidyl-proline dioxygenase activity	1/202	12/18367	0.124313301480175	0.392963523470889	EGLN3	1
GO:0061578	Lys63-specific deubiquitinase activity	1/202	12/18367	0.124313301480175	0.392963523470889	YOD1	1
GO:0089720	caspase binding	1/202	12/18367	0.124313301480175	0.392963523470889	RIOK3	1
GO:0008179	adenylate cyclase binding	1/202	13/18367	0.133950387456803	0.400732882692703	CALM3	1
GO:0008253	5'-nucleotidase activity	1/202	13/18367	0.133950387456803	0.400732882692703	NT5C3A	1
GO:0031432	titin binding	1/202	13/18367	0.133950387456803	0.400732882692703	CALM3	1
GO:0032036	myosin heavy chain binding	1/202	13/18367	0.133950387456803	0.400732882692703	MYL9	1
GO:0034236	protein kinase A catalytic subunit binding	1/202	13/18367	0.133950387456803	0.400732882692703	PRKAR2B	1
GO:0034450	ubiquitin-ubiquitin ligase activity	1/202	13/18367	0.133950387456803	0.400732882692703	PELI2	1
GO:0052650	NADP-retinol dehydrogenase activity	1/202	13/18367	0.133950387456803	0.400732882692703	RDH11	1
GO:0072542	protein phosphatase activator activity	1/202	13/18367	0.133950387456803	0.400732882692703	CALM3	1
GO:0004674	protein serine/threonine kinase activity	7/202	386/18367	0.134428440478656	0.400732882692703	MYLK/TNIK/CLK1/LTBP1/RIOK3/BMP2K/MAP4K5	7
GO:0004089	carbonate dehydratase activity	1/202	14/18367	0.143481934897891	0.409205586514278	CA2	1
GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	1/202	14/18367	0.143481934897891	0.409205586514278	B3GNT2	1
GO:0015562	efflux transmembrane transporter activity	1/202	14/18367	0.143481934897891	0.409205586514278	ABCC4	1
GO:0032977	membrane insertase activity	1/202	14/18367	0.143481934897891	0.409205586514278	EMC3	1
GO:0035259	glucocorticoid receptor binding	1/202	14/18367	0.143481934897891	0.409205586514278	STAT3	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/202	14/18367	0.143481934897891	0.409205586514278	P2RY1	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/202	14/18367	0.143481934897891	0.409205586514278	PDE5A	1
GO:1990841	promoter-specific chromatin binding	2/202	62/18367	0.148723435366961	0.409205586514278	GADD45A/GTF2B	2
GO:0005041	low-density lipoprotein particle receptor activity	1/202	15/18367	0.152909093899178	0.409205586514278	LRP12	1
GO:0005161	platelet-derived growth factor receptor binding	1/202	15/18367	0.152909093899178	0.409205586514278	PDGFA	1
GO:0005545	1-phosphatidylinositol binding	1/202	15/18367	0.152909093899178	0.409205586514278	EPB41	1
GO:0008252	nucleotidase activity	1/202	15/18367	0.152909093899178	0.409205586514278	NT5C3A	1
GO:0008559	ABC-type xenobiotic transporter activity	1/202	15/18367	0.152909093899178	0.409205586514278	ABCC4	1
GO:0010851	cyclase regulator activity	1/202	15/18367	0.152909093899178	0.409205586514278	CALM3	1
GO:0030553	cGMP binding	1/202	15/18367	0.152909093899178	0.409205586514278	PDE5A	1
GO:0051371	muscle alpha-actinin binding	1/202	15/18367	0.152909093899178	0.409205586514278	PDLIM1	1
GO:0070742	C2H2 zinc finger domain binding	1/202	15/18367	0.152909093899178	0.409205586514278	GATA1	1
GO:1904680	peptide transmembrane transporter activity	1/202	15/18367	0.152909093899178	0.409205586514278	ABCC4	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	3/202	124/18367	0.156445562297132	0.415281217294528	BTK/FYN/CLK1	3
GO:0000900	translation repressor activity, mRNA regulatory element binding	1/202	16/18367	0.162233002085336	0.415281217294528	CPEB4	1
GO:0005159	insulin-like growth factor receptor binding	1/202	16/18367	0.162233002085336	0.415281217294528	SOCS2	1
GO:0005521	lamin binding	1/202	16/18367	0.162233002085336	0.415281217294528	BNIP3L	1
GO:0016307	phosphatidylinositol phosphate kinase activity	1/202	16/18367	0.162233002085336	0.415281217294528	PIP4K2A	1
GO:0046935	1-phosphatidylinositol-3-kinase regulator activity	1/202	16/18367	0.162233002085336	0.415281217294528	SOCS2	1
GO:0050700	CARD domain binding	1/202	16/18367	0.162233002085336	0.415281217294528	CARD19	1
GO:1990380	Lys48-specific deubiquitinase activity	1/202	16/18367	0.162233002085336	0.415281217294528	YOD1	1
GO:0002039	p53 binding	2/202	66/18367	0.164124289824285	0.416263936158097	GATA1/RCHY1	2
GO:0000400	four-way junction DNA binding	1/202	17/18367	0.171454784744524	0.416263936158097	HMGB1	1
GO:0003951	NAD+ kinase activity	1/202	17/18367	0.171454784744524	0.416263936158097	DGKD	1
GO:0008308	voltage-gated anion channel activity	1/202	17/18367	0.171454784744524	0.416263936158097	CLCN3	1
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/202	17/18367	0.171454784744524	0.416263936158097	ATP2A3	1
GO:0016722	oxidoreductase activity, acting on metal ions	1/202	17/18367	0.171454784744524	0.416263936158097	FTH1	1
GO:0030169	low-density lipoprotein particle binding	1/202	17/18367	0.171454784744524	0.416263936158097	THBS1	1
GO:0043024	ribosomal small subunit binding	1/202	17/18367	0.171454784744524	0.416263936158097	EIF1B	1
GO:0048531	beta-1,3-galactosyltransferase activity	1/202	17/18367	0.171454784744524	0.416263936158097	B3GNT2	1
GO:0050780	dopamine receptor binding	1/202	17/18367	0.171454784744524	0.416263936158097	GNA13	1
GO:0017124	SH3 domain binding	3/202	130/18367	0.172448661907716	0.41652984491556	ARHGAP6/RUFY1/GPX1	3
GO:0016755	aminoacyltransferase activity	1/202	18/18367	0.180575554961505	0.425009954702691	F13A1	1
GO:0030228	lipoprotein particle receptor activity	1/202	18/18367	0.180575554961505	0.425009954702691	LRP12	1
GO:0098641	cadherin binding involved in cell-cell adhesion	1/202	18/18367	0.180575554961505	0.425009954702691	PDLIM1	1
GO:0098918	structural constituent of synapse	1/202	18/18367	0.180575554961505	0.425009954702691	DNM3	1
GO:0005516	calmodulin binding	4/202	201/18367	0.180993058290892	0.425009954702691	NRGN/MYLK/EPB41/MBP	4
GO:0048029	monosaccharide binding	2/202	71/18367	0.183743779923518	0.425009954702691	EGLN3/SLC2A3	2
GO:0004713	protein tyrosine kinase activity	3/202	136/18367	0.188893299700824	0.425009954702691	BTK/FYN/CLK1	3
GO:0000339	RNA cap binding	1/202	19/18367	0.189596413749329	0.425009954702691	EIF4E	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/202	19/18367	0.189596413749329	0.425009954702691	LTBP1	1
GO:0004745	NAD-retinol dehydrogenase activity	1/202	19/18367	0.189596413749329	0.425009954702691	RDH11	1
GO:0035064	methylated histone binding	2/202	73/18367	0.191685527696173	0.425009954702691	MBTD1/ZMYND8	2
GO:0070063	RNA polymerase binding	2/202	73/18367	0.191685527696173	0.425009954702691	GTF2B/STOM	2
GO:0140034	methylation-dependent protein binding	2/202	73/18367	0.191685527696173	0.425009954702691	MBTD1/ZMYND8	2
GO:0140104	molecular carrier activity	2/202	73/18367	0.191685527696173	0.425009954702691	CLU/EMC3	2
GO:0003725	double-stranded RNA binding	2/202	74/18367	0.195673499170346	0.425009954702691	MBNL1/HMGB1	2
GO:0019955	cytokine binding	3/202	139/18367	0.197263035311924	0.425009954702691	THBS1/LTBP1/HMGB1	3
GO:0016505	peptidase activator activity involved in apoptotic process	1/202	20/18367	0.198518450179601	0.425009954702691	ATP2A3	1
GO:0019211	phosphatase activator activity	1/202	20/18367	0.198518450179601	0.425009954702691	CALM3	1
GO:0031418	L-ascorbic acid binding	1/202	20/18367	0.198518450179601	0.425009954702691	EGLN3	1
GO:0031683	G-protein beta/gamma-subunit complex binding	1/202	20/18367	0.198518450179601	0.425009954702691	GNA13	1
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/202	20/18367	0.198518450179601	0.425009954702691	SOCS2	1
GO:0042288	MHC class I protein binding	1/202	20/18367	0.198518450179601	0.425009954702691	HLA-E	1
GO:0050145	nucleoside monophosphate kinase activity	1/202	20/18367	0.198518450179601	0.425009954702691	TJP2	1
GO:0070300	phosphatidic acid binding	1/202	20/18367	0.198518450179601	0.425009954702691	NRGN	1
GO:0097001	ceramide binding	1/202	20/18367	0.198518450179601	0.425009954702691	LAPTM4B	1
GO:0045182	translation regulator activity	3/202	140/18367	0.20007302074088	0.426399967280337	EIF1B/EIF4E/CPEB4	3
GO:0019838	growth factor binding	3/202	141/18367	0.202892606919312	0.430213353532374	THBS1/LTBP1/PDGFA	3
GO:0001614	purinergic nucleotide receptor activity	1/202	21/18367	0.207342741511357	0.430213353532374	P2RY1	1
GO:0015125	bile acid transmembrane transporter activity	1/202	21/18367	0.207342741511357	0.430213353532374	ABCC4	1
GO:0015216	purine nucleotide transmembrane transporter activity	1/202	21/18367	0.207342741511357	0.430213353532374	ABCC4	1
GO:0016502	nucleotide receptor activity	1/202	21/18367	0.207342741511357	0.430213353532374	P2RY1	1
GO:0051428	peptide hormone receptor binding	1/202	21/18367	0.207342741511357	0.430213353532374	FYN	1
GO:0004602	glutathione peroxidase activity	1/202	22/18367	0.216070353318547	0.434910839371946	GPX1	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/202	22/18367	0.216070353318547	0.434910839371946	RDH11	1
GO:0030742	GTP-dependent protein binding	1/202	22/18367	0.216070353318547	0.434910839371946	RAB32	1
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/202	22/18367	0.216070353318547	0.434910839371946	SNCA	1
GO:0050321	tau-protein kinase activity	1/202	22/18367	0.216070353318547	0.434910839371946	FYN	1
GO:0070182	DNA polymerase binding	1/202	22/18367	0.216070353318547	0.434910839371946	HMGB1	1
GO:0072349	modified amino acid transmembrane transporter activity	1/202	22/18367	0.216070353318547	0.434910839371946	ABCC4	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/202	23/18367	0.224702339616157	0.437333892393429	PDE5A	1
GO:0015299	solute:proton antiporter activity	1/202	23/18367	0.224702339616157	0.437333892393429	CLCN3	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/202	23/18367	0.224702339616157	0.437333892393429	ALOX12	1
GO:0017134	fibroblast growth factor binding	1/202	23/18367	0.224702339616157	0.437333892393429	THBS1	1
GO:0030552	cAMP binding	1/202	23/18367	0.224702339616157	0.437333892393429	PRKAR2B	1
GO:0050750	low-density lipoprotein particle receptor binding	1/202	23/18367	0.224702339616157	0.437333892393429	CLU	1
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	1/202	23/18367	0.224702339616157	0.437333892393429	UIMC1	1
GO:0140103	catalytic activity, acting on a glycoprotein	1/202	23/18367	0.224702339616157	0.437333892393429	MGAT4B	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	7/202	450/18367	0.227636372263257	0.441221116609029	GATA1/HHEX/E2F3/ELF1/ZNF267/STAT3/CREBRF	7
GO:0005085	guanyl-nucleotide exchange factor activity	4/202	223/18367	0.230956144847897	0.444760805449075	RASGRP2/DENND4A/HERC1/GNA13	4
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/202	24/18367	0.233239742984971	0.444760805449075	ALOX12	1
GO:0019789	SUMO transferase activity	1/202	24/18367	0.233239742984971	0.444760805449075	KIAA1586	1
GO:0070840	dynein complex binding	1/202	24/18367	0.233239742984971	0.444760805449075	SNCA	1
GO:0001540	amyloid-beta binding	2/202	84/18367	0.236014817886071	0.448237819452982	CLU/PGRMC1	2
GO:0001216	DNA-binding transcription activator activity	7/202	456/18367	0.237361367043541	0.448984754528144	GATA1/HHEX/E2F3/ELF1/ZNF267/STAT3/CREBRF	7
GO:0008013	beta-catenin binding	2/202	85/18367	0.240080900203667	0.449932700005315	VCL/TBL1XR1	2
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/202	25/18367	0.241683594694999	0.449932700005315	PDE5A	1
GO:0005160	transforming growth factor beta receptor binding	1/202	25/18367	0.241683594694999	0.449932700005315	TGFB1	1
GO:0034237	protein kinase A regulatory subunit binding	1/202	25/18367	0.241683594694999	0.449932700005315	C2orf88	1
GO:0016209	antioxidant activity	2/202	86/18367	0.244150376907058	0.452735541430016	PTGS1/GPX1	2
GO:0005096	GTPase activator activity	7/202	462/18367	0.247221410649953	0.454696698392994	ARHGAP6/RGS18/RASGRP2/RGS10/DENND4A/HERC1/GNA13	7
GO:0061134	peptidase regulator activity	4/202	230/18367	0.247532494019805	0.454696698392994	ATP2A3/LXN/SNCA/TIMP1	4
GO:0004435	phosphatidylinositol phospholipase C activity	1/202	26/18367	0.25003491482757	0.454696698392994	CCL5	1
GO:0030371	translation repressor activity	1/202	26/18367	0.25003491482757	0.454696698392994	CPEB4	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/202	26/18367	0.25003491482757	0.454696698392994	ABCC4	1
GO:0008081	phosphoric diester hydrolase activity	2/202	89/18367	0.256373598949278	0.457356426836744	PDE5A/CCL5	2
GO:0051117	ATPase binding	2/202	89/18367	0.256373598949278	0.457356426836744	BBC3/ATP1B1	2
GO:0001671	ATPase activator activity	1/202	27/18367	0.258294712396123	0.457356426836744	ATP1B1	1
GO:0015215	nucleotide transmembrane transporter activity	1/202	27/18367	0.258294712396123	0.457356426836744	ABCC4	1
GO:0030507	spectrin binding	1/202	27/18367	0.258294712396123	0.457356426836744	EPB41	1
GO:0051393	alpha-actinin binding	1/202	27/18367	0.258294712396123	0.457356426836744	PDLIM1	1
GO:0070006	metalloaminopeptidase activity	1/202	27/18367	0.258294712396123	0.457356426836744	XPNPEP1	1
GO:0001968	fibronectin binding	1/202	28/18367	0.266463985465697	0.459723579319938	THBS1	1
GO:0003953	NAD+ nucleosidase activity	1/202	28/18367	0.266463985465697	0.459723579319938	BANK1	1
GO:0004629	phospholipase C activity	1/202	28/18367	0.266463985465697	0.459723579319938	CCL5	1
GO:0043236	laminin binding	1/202	28/18367	0.266463985465697	0.459723579319938	THBS1	1
GO:0046875	ephrin receptor binding	1/202	28/18367	0.266463985465697	0.459723579319938	FYN	1
GO:0070325	lipoprotein particle receptor binding	1/202	28/18367	0.266463985465697	0.459723579319938	CLU	1
GO:1990756	ubiquitin ligase-substrate adaptor activity	1/202	28/18367	0.266463985465697	0.459723579319938	ANKRD9	1
GO:0043130	ubiquitin binding	2/202	92/18367	0.26860779133047	0.461730911374641	STAM/ZFAND2B	2
GO:0004033	aldo-keto reductase (NADP) activity	1/202	29/18367	0.274543721271135	0.465144218412606	RDH11	1
GO:0035250	UDP-galactosyltransferase activity	1/202	29/18367	0.274543721271135	0.465144218412606	B3GNT2	1
GO:0046625	sphingolipid binding	1/202	29/18367	0.274543721271135	0.465144218412606	LAPTM4B	1
GO:0051787	misfolded protein binding	1/202	29/18367	0.274543721271135	0.465144218412606	CLU	1
GO:0008201	heparin binding	3/202	166/18367	0.275769047386597	0.465545596125761	PF4/THBS1/LXN	3
GO:0046966	thyroid hormone receptor binding	1/202	30/18367	0.282534896334022	0.474588856812869	GTF2B	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	3/202	170/18367	0.287717146571883	0.474588856812869	PTGS1/FAXDC2/EGLN3	3
GO:0022804	active transmembrane transporter activity	6/202	406/18367	0.289571011418934	0.474588856812869	ABCC4/ATP2A3/ATP1B1/ATP2C1/CLCN3/UQCRH	6
GO:0005164	tumor necrosis factor receptor binding	1/202	31/18367	0.290438476578365	0.474588856812869	TNFSF4	1
GO:0042910	xenobiotic transmembrane transporter activity	1/202	31/18367	0.290438476578365	0.474588856812869	ABCC4	1
GO:0071813	lipoprotein particle binding	1/202	31/18367	0.290438476578365	0.474588856812869	THBS1	1
GO:0071814	protein-lipid complex binding	1/202	31/18367	0.290438476578365	0.474588856812869	THBS1	1
GO:0090482	vitamin transmembrane transporter activity	1/202	31/18367	0.290438476578365	0.474588856812869	SLC2A3	1
GO:0030695	GTPase regulator activity	7/202	488/18367	0.291293963258105	0.474588856812869	ARHGAP6/RGS18/RASGRP2/RGS10/DENND4A/HERC1/GNA13	7
GO:0060589	nucleoside-triphosphatase regulator activity	7/202	488/18367	0.291293963258105	0.474588856812869	ARHGAP6/RGS18/RASGRP2/RGS10/DENND4A/HERC1/GNA13	7
GO:0003712	transcription coregulator activity	7/202	489/18367	0.29302658576833	0.474588856812869	NCOA4/ZMYND8/AKIRIN2/HMGB1/PDLIM1/RYBP/TBL1XR1	7
GO:0005201	extracellular matrix structural constituent	3/202	172/18367	0.293707096953074	0.474588856812869	THBS1/LTBP1/SPARC	3
GO:0008378	galactosyltransferase activity	1/202	32/18367	0.29825541744503	0.474588856812869	B3GNT2	1
GO:0015605	organophosphate ester transmembrane transporter activity	1/202	32/18367	0.29825541744503	0.474588856812869	ABCC4	1
GO:0048019	receptor antagonist activity	1/202	32/18367	0.29825541744503	0.474588856812869	CCL5	1
GO:0050699	WW domain binding	1/202	32/18367	0.29825541744503	0.474588856812869	NFE2	1
GO:0140658	ATP-dependent chromatin remodeler activity	1/202	32/18367	0.29825541744503	0.474588856812869	CHD9	1
GO:0001530	lipopolysaccharide binding	1/202	33/18367	0.305986664004949	0.483623217269567	HMGB1	1
GO:0019956	chemokine binding	1/202	33/18367	0.305986664004949	0.483623217269567	HMGB1	1
GO:0031490	chromatin DNA binding	2/202	103/18367	0.313348766562795	0.492404047181643	GATA1/STAT3	2
GO:0016831	carboxy-lyase activity	1/202	34/18367	0.31363315107111	0.492404047181643	ODC1	1
GO:0004866	endopeptidase inhibitor activity	3/202	180/18367	0.31773457241509	0.49718599205152	LXN/SNCA/TIMP1	3
GO:0015298	solute:cation antiporter activity	1/202	35/18367	0.321195803309349	0.498010251335158	CLCN3	1
GO:0042887	amide transmembrane transporter activity	1/202	35/18367	0.321195803309349	0.498010251335158	ABCC4	1
GO:1990782	protein tyrosine kinase binding	2/202	105/18367	0.321433368165367	0.498010251335158	BANK1/TJP2	2
GO:0000217	DNA secondary structure binding	1/202	36/18367	0.328675535347944	0.500990864559487	HMGB1	1
GO:0005484	SNAP receptor activity	1/202	36/18367	0.328675535347944	0.500990864559487	BET1	1
GO:0042605	peptide antigen binding	1/202	36/18367	0.328675535347944	0.500990864559487	HLA-E	1
GO:0042805	actinin binding	1/202	36/18367	0.328675535347944	0.500990864559487	PDLIM1	1
GO:0043394	proteoglycan binding	1/202	36/18367	0.328675535347944	0.500990864559487	THBS1	1
GO:0043531	ADP binding	1/202	37/18367	0.336073251886033	0.508972674078204	P2RY1	1
GO:0046915	transition metal ion transmembrane transporter activity	1/202	37/18367	0.336073251886033	0.508972674078204	ATP2C1	1
GO:0003714	transcription corepressor activity	3/202	187/18367	0.338789437296986	0.50980774749802	ZMYND8/RYBP/TBL1XR1	3
GO:0030414	peptidase inhibitor activity	3/202	187/18367	0.338789437296986	0.50980774749802	LXN/SNCA/TIMP1	3
GO:0000149	SNARE binding	2/202	110/18367	0.341536819572732	0.512305229359098	SNCA/RAB11A	2
GO:0032182	ubiquitin-like protein binding	2/202	111/18367	0.345536228941519	0.516338232777559	STAM/ZFAND2B	2
GO:0008017	microtubule binding	4/202	271/18367	0.348307112104168	0.516338232777559	DNM3/KIF2A/SNCA/RAB11A	4
GO:0030246	carbohydrate binding	4/202	271/18367	0.348307112104168	0.516338232777559	CLEC1B/LGALSL/EGLN3/SLC2A3	4
GO:0004402	histone acetyltransferase activity	1/202	39/18367	0.350626208253938	0.516338232777559	GTF2B	1
GO:0016776	phosphotransferase activity, phosphate group as acceptor	1/202	39/18367	0.350626208253938	0.516338232777559	TJP2	1
GO:0016887	ATP hydrolysis activity	4/202	272/18367	0.350803045623819	0.516338232777559	ATP2A3/KIF2A/ATP2C1/CHD9	4
GO:0004177	aminopeptidase activity	1/202	40/18367	0.357783208795879	0.521721025829285	XPNPEP1	1
GO:0042169	SH2 domain binding	1/202	40/18367	0.357783208795879	0.521721025829285	RUFY1	1
GO:0042287	MHC protein binding	1/202	40/18367	0.357783208795879	0.521721025829285	HLA-E	1
GO:0061135	endopeptidase regulator activity	3/202	194/18367	0.359807325623528	0.523053241878648	LXN/SNCA/TIMP1	3
GO:0106310	protein serine kinase activity	5/202	360/18367	0.363053766285313	0.52367961608096	TNIK/CLK1/RIOK3/BMP2K/MAP4K5	5
GO:0048487	beta-tubulin binding	1/202	41/18367	0.364861715470362	0.52367961608096	SNCA	1
GO:0061733	peptide-lysine-N-acetyltransferase activity	1/202	41/18367	0.364861715470362	0.52367961608096	GTF2B	1
GO:0016829	lyase activity	3/202	196/18367	0.365797438833622	0.52367961608096	CA2/ODC1/HMGB1	3
GO:0019902	phosphatase binding	3/202	196/18367	0.365797438833622	0.52367961608096	CNST/KIFAP3/STAT3	3
GO:0019205	nucleobase-containing compound kinase activity	1/202	42/18367	0.371862584916776	0.530749325744852	TJP2	1
GO:0005246	calcium channel regulator activity	1/202	43/18367	0.378786664471854	0.532562743182815	YWHAE	1
GO:0016504	peptidase activator activity	1/202	43/18367	0.378786664471854	0.532562743182815	ATP2A3	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/202	43/18367	0.378786664471854	0.532562743182815	FAXDC2	1
GO:0030544	Hsp70 protein binding	1/202	43/18367	0.378786664471854	0.532562743182815	SNCA	1
GO:0030547	signaling receptor inhibitor activity	1/202	43/18367	0.378786664471854	0.532562743182815	CCL5	1
GO:0004712	protein serine/threonine/tyrosine kinase activity	1/202	44/18367	0.385634792270189	0.54057734273589	CLK1	1
GO:0003697	single-stranded DNA binding	2/202	123/18367	0.392833060921599	0.549033743899326	SSBP2/HMGB1	2
GO:0015631	tubulin binding	5/202	375/18367	0.395777001941058	0.551178741002494	DNM3/KIF2A/FYN/SNCA/RAB11A	5
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/202	124/18367	0.396708265817082	0.551178741002494	ABCC4/RDH11	2
GO:0042826	histone deacetylase binding	2/202	127/18367	0.408265063632956	0.565567191091536	TAL1/YWHAE	2
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	4/202	299/18367	0.417952798108359	0.570533133096126	TAL1/GATA1/GTF2B/STAT3	4
GO:0032813	tumor necrosis factor receptor superfamily binding	1/202	49/18367	0.418764857911581	0.570533133096126	TNFSF4	1
GO:0034212	peptide N-acetyltransferase activity	1/202	49/18367	0.418764857911581	0.570533133096126	GTF2B	1
GO:0043539	protein serine/threonine kinase activator activity	1/202	49/18367	0.418764857911581	0.570533133096126	CALM3	1
GO:0015078	proton transmembrane transporter activity	2/202	130/18367	0.419714211644956	0.570533133096126	CLCN3/UQCRH	2
GO:0000993	RNA polymerase II complex binding	1/202	50/18367	0.425174373071635	0.570533133096126	GTF2B	1
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/202	50/18367	0.425174373071635	0.570533133096126	ABCC4	1
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/202	50/18367	0.425174373071635	0.570533133096126	CDKN2D	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	1/202	50/18367	0.425174373071635	0.570533133096126	BANK1	1
GO:0030159	signaling receptor complex adaptor activity	1/202	50/18367	0.425174373071635	0.570533133096126	LAT	1
GO:0140359	ABC-type transporter activity	1/202	50/18367	0.425174373071635	0.570533133096126	ABCC4	1
GO:0004879	nuclear receptor activity	1/202	52/18367	0.437783168635913	0.580206828461226	STAT3	1
GO:0016830	carbon-carbon lyase activity	1/202	52/18367	0.437783168635913	0.580206828461226	ODC1	1
GO:0098531	ligand-activated transcription factor activity	1/202	52/18367	0.437783168635913	0.580206828461226	STAT3	1
GO:1901682	sulfur compound transmembrane transporter activity	1/202	52/18367	0.437783168635913	0.580206828461226	ABCC4	1
GO:0015085	calcium ion transmembrane transporter activity	2/202	135/18367	0.438542740832689	0.580206828461226	ATP2A3/ATP2C1	2
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	2/202	136/18367	0.442268851894358	0.583497560902641	ABCC4/RDH11	2
GO:1901618	organic hydroxy compound transmembrane transporter activity	1/202	53/18367	0.443983976713202	0.5837358944378	ABCC4	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	4/202	310/18367	0.444928208286986	0.5837358944378	ZNF778/HHEX/MAX/ZEB2	4
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	1/202	54/18367	0.450116729618298	0.588250593778431	EGLN3	1
GO:0001217	DNA-binding transcription repressor activity	4/202	313/18367	0.452222846565856	0.588250593778431	ZNF778/HHEX/MAX/ZEB2	4
GO:0020037	heme binding	2/202	139/18367	0.453365107306943	0.588250593778431	PTGS1/PGRMC1	2
GO:0099106	ion channel regulator activity	2/202	139/18367	0.453365107306943	0.588250593778431	YWHAE/FLNA	2
GO:0061659	ubiquitin-like protein ligase activity	4/202	316/18367	0.459486985140901	0.593153317157158	PELI2/TRIM58/RCHY1/KIAA1586	4
GO:0070851	growth factor receptor binding	2/202	141/18367	0.46069274668337	0.593153317157158	FYN/PDGFA	2
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/202	56/18367	0.462181034812478	0.593153317157158	SNCA	1
GO:0045309	protein phosphorylated amino acid binding	1/202	56/18367	0.462181034812478	0.593153317157158	YWHAE	1
GO:0005539	glycosaminoglycan binding	3/202	230/18367	0.465324670423311	0.595564999373314	PF4/THBS1/LXN	3
GO:0008194	UDP-glycosyltransferase activity	2/202	143/18367	0.467963215958697	0.595896533214627	B3GNT2/MGAT4B	2
GO:0043175	RNA polymerase core enzyme binding	1/202	57/18367	0.468114049446735	0.595896533214627	GTF2B	1
GO:0016922	nuclear receptor binding	2/202	144/18367	0.471576692523417	0.598686313149675	GTF2B/STAT3	2
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/202	58/18367	0.473981933772882	0.600020540573601	ABCC4	1
GO:0016247	channel regulator activity	2/202	145/18367	0.475175502407544	0.600020540573601	YWHAE/FLNA	2
GO:0036002	pre-mRNA binding	1/202	59/18367	0.479785399247669	0.604221719373402	CELF2	1
GO:0043021	ribonucleoprotein complex binding	2/202	149/18367	0.489421828847254	0.612053137296542	EIF1B/CPEB4	2
GO:0046906	tetrapyrrole binding	2/202	149/18367	0.489421828847254	0.612053137296542	PTGS1/PGRMC1	2
GO:0005507	copper ion binding	1/202	61/18367	0.491201880887671	0.612053137296542	SNCA	1
GO:0043621	protein self-association	1/202	61/18367	0.491201880887671	0.612053137296542	CCL5	1
GO:0019903	protein phosphatase binding	2/202	150/18367	0.492945657242375	0.612605289079574	KIFAP3/STAT3	2
GO:0015103	inorganic anion transmembrane transporter activity	2/202	152/18367	0.499947331920535	0.619671561406769	ABCC4/CLCN3	2
GO:0016836	hydro-lyase activity	1/202	64/18367	0.507860808170294	0.627827928210521	CA2	1
GO:0030145	manganese ion binding	1/202	65/18367	0.513292273872616	0.632881311502623	XPNPEP1	1
GO:0043022	ribosome binding	1/202	66/18367	0.518664089011821	0.637834950194694	CPEB4	1
GO:0003684	damaged DNA binding	1/202	68/18367	0.529231368044499	0.64744928402327	HMGB1	1
GO:0008080	N-acetyltransferase activity	1/202	68/18367	0.529231368044499	0.64744928402327	GTF2B	1
GO:0003777	microtubule motor activity	1/202	69/18367	0.534428114514525	0.652113062011247	KIF2A	1
GO:0001098	basal transcription machinery binding	1/202	70/18367	0.539567775727121	0.653306998373969	GTF2B	1
GO:0001099	basal RNA polymerase II transcription machinery binding	1/202	70/18367	0.539567775727121	0.653306998373969	GTF2B	1
GO:0004857	enzyme inhibitor activity	1/202	70/18367	0.539567775727121	0.653306998373969	OAZ1	1
GO:0031267	small GTPase binding	3/202	259/18367	0.544530775587323	0.657625628978536	CORO1C/DAAM1/FLNA	3
GO:0003678	DNA helicase activity	1/202	72/18367	0.549678331532674	0.658774794279617	CHD9	1
GO:0008235	metalloexopeptidase activity	1/202	72/18367	0.549678331532674	0.658774794279617	XPNPEP1	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	1/202	72/18367	0.549678331532674	0.658774794279617	UQCRH	1
GO:0003713	transcription coactivator activity	3/202	262/18367	0.552336242107834	0.660280126986777	NCOA4/HMGB1/PDLIM1	3
GO:0005254	chloride channel activity	1/202	74/18367	0.559567946337467	0.664457315464511	CLCN3	1
GO:0019905	syntaxin binding	1/202	74/18367	0.559567946337467	0.664457315464511	RAB11A	1
GO:1901681	sulfur compound binding	3/202	265/18367	0.560062747854375	0.664457315464511	PF4/THBS1/LXN	3
GO:0003823	antigen binding	2/202	171/18367	0.56329846534932	0.666617028089271	TGFB1/HLA-E	2
GO:0019787	ubiquitin-like protein transferase activity	5/202	458/18367	0.569259230692119	0.671982700892201	PELI2/TRIM58/RCHY1/HERC1/KIAA1586	5
GO:0038024	cargo receptor activity	1/202	77/18367	0.573998585778074	0.675883334753682	LRP12	1
GO:0016835	carbon-oxygen lyase activity	1/202	79/18367	0.583356641460038	0.681789027612104	CA2	1
GO:0034987	immunoglobulin receptor binding	1/202	79/18367	0.583356641460038	0.681789027612104	FLNA	1
GO:0046332	SMAD binding	1/202	79/18367	0.583356641460038	0.681789027612104	FLNA	1
GO:0030165	PDZ domain binding	1/202	84/18367	0.60586647466522	0.704979864387162	CLCN3	1
GO:0008514	organic anion transmembrane transporter activity	2/202	185/18367	0.606192877020808	0.704979864387162	ABCC4/SLC2A3	2
GO:0008022	protein C-terminus binding	2/202	189/18367	0.617850165851508	0.714335154695427	ATP1B1/EPB41	2
GO:0003727	single-stranded RNA binding	1/202	87/18367	0.618787140373109	0.714335154695427	HMGB1	1
GO:0005253	anion channel activity	1/202	87/18367	0.618787140373109	0.714335154695427	CLCN3	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	1/202	88/18367	0.622999667596557	0.714591447098801	GMPR	1
GO:0048306	calcium-dependent protein binding	1/202	88/18367	0.622999667596557	0.714591447098801	CALM3	1
GO:0051020	GTPase binding	3/202	291/18367	0.623560689506597	0.714591447098801	CORO1C/DAAM1/FLNA	3
GO:0015297	antiporter activity	1/202	89/18367	0.627165872922094	0.715242436189604	CLCN3	1
GO:0019888	protein phosphatase regulator activity	1/202	89/18367	0.627165872922094	0.715242436189604	CALM3	1
GO:0016407	acetyltransferase activity	1/202	91/18367	0.635361339799107	0.722838625713477	GTF2B	1
GO:0016758	hexosyltransferase activity	2/202	197/18367	0.640369548909753	0.72678086153372	B3GNT2/MGAT4B	2
GO:0033218	amide binding	4/202	400/18367	0.644440529756122	0.729643003642147	LAPTM4B/CLU/PGRMC1/HLA-E	4
GO:0016410	N-acyltransferase activity	1/202	94/18367	0.647319619263744	0.73114518147056	GTF2B	1
GO:0003730	mRNA 3'-UTR binding	2/202	201/18367	0.651234099437327	0.733806844102825	CELF2/CPEB4	2
GO:0061630	ubiquitin protein ligase activity	3/202	304/18367	0.652884382326286	0.733910606385873	PELI2/TRIM58/RCHY1	3
GO:0005496	steroid binding	1/202	100/18367	0.670077978075715	0.751444589699195	PGRMC1	1
GO:0008509	anion transmembrane transporter activity	3/202	314/18367	0.674313988513438	0.754398785249001	ABCC4/SLC2A3/CLCN3	3
GO:0004497	monooxygenase activity	1/202	102/18367	0.677334513912616	0.755982360314792	FAXDC2	1
GO:0008238	exopeptidase activity	1/202	103/18367	0.680903001631732	0.758168590469375	XPNPEP1	1
GO:0004620	phospholipase activity	1/202	104/18367	0.684432217229103	0.760300882818178	CCL5	1
GO:0042277	peptide binding	3/202	321/18367	0.688730005843766	0.763274900593915	CLU/PGRMC1/HLA-E	3
GO:0051087	chaperone binding	1/202	107/18367	0.694788508639782	0.766382640677605	CLU	1
GO:1902936	phosphatidylinositol bisphosphate binding	1/202	107/18367	0.694788508639782	0.766382640677605	LAPTM4B	1
GO:0000287	magnesium ion binding	2/202	221/18367	0.701686746541026	0.772183312198185	NT5C3A/SNCA	2
GO:0004842	ubiquitin-protein transferase activity	4/202	433/18367	0.704709480290749	0.773702016822711	PELI2/TRIM58/RCHY1/HERC1	4
GO:0008094	ATP-dependent activity, acting on DNA	1/202	111/18367	0.708072648999163	0.775586552740944	CHD9	1
GO:0004843	thiol-dependent deubiquitinase	1/202	113/18367	0.714497350868127	0.780638165645802	YOD1	1
GO:0003774	cytoskeletal motor activity	1/202	114/18367	0.717656742515143	0.780638165645802	KIF2A	1
GO:0101005	deubiquitinase activity	1/202	114/18367	0.717656742515143	0.780638165645802	YOD1	1
GO:0051082	unfolded protein binding	1/202	122/18367	0.741710909475963	0.804944328025757	CLU	1
GO:0140101	catalytic activity, acting on a tRNA	1/202	124/18367	0.7473987127378	0.809252399309204	NT5C3A	1
GO:0019783	ubiquitin-like protein-specific protease activity	1/202	125/18367	0.750195701173198	0.809691874884102	YOD1	1
GO:0008242	omega peptidase activity	1/202	126/18367	0.75296187091133	0.809691874884102	YOD1	1
GO:0009055	electron transfer activity	1/202	126/18367	0.75296187091133	0.809691874884102	UQCRH	1
GO:0140678	molecular function inhibitor activity	1/202	128/18367	0.758403102232364	0.812852898580387	OAZ1	1
GO:0016298	lipase activity	1/202	129/18367	0.761078828607114	0.812852898580387	CCL5	1
GO:0031072	heat shock protein binding	1/202	129/18367	0.761078828607114	0.812852898580387	SNCA	1
GO:0016746	acyltransferase activity	2/202	250/18367	0.763978662279368	0.814103959125752	F13A1/GTF2B	2
GO:0042578	phosphoric ester hydrolase activity	3/202	366/18367	0.770129153013042	0.818805487740729	PDE5A/CCL5/NT5C3A	3
GO:0043177	organic acid binding	1/202	135/18367	0.776525113351895	0.823746235109781	EGLN3	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	1/202	144/18367	0.797850884157441	0.844466890872257	BANK1	1
GO:0016757	glycosyltransferase activity	2/202	270/18367	0.800109431998802	0.844958615406807	B3GNT2/MGAT4B	2
GO:0008528	G protein-coupled peptide receptor activity	1/202	147/18367	0.804499406953704	0.845801831864274	F2R	1
GO:0052689	carboxylic ester hydrolase activity	1/202	147/18367	0.804499406953704	0.845801831864274	CA2	1
GO:0019842	vitamin binding	1/202	148/18367	0.806666866876611	0.846191746768115	EGLN3	1
GO:0015081	sodium ion transmembrane transporter activity	1/202	152/18367	0.815100193711083	0.853138202750933	ATP1B1	1
GO:0001653	peptide receptor activity	1/202	153/18367	0.817150688406134	0.853387969488446	F2R	1
GO:0005319	lipid transporter activity	1/202	154/18367	0.819178554934187	0.853613051712394	ABCC4	1
GO:0015079	potassium ion transmembrane transporter activity	1/202	155/18367	0.82118404177893	0.853813871253589	ATP1B1	1
GO:0004386	helicase activity	1/202	156/18367	0.823167394708902	0.853990843409456	CHD9	1
GO:0046943	carboxylic acid transmembrane transporter activity	1/202	163/18367	0.836451203473814	0.865840556548767	ABCC4	1
GO:0005342	organic acid transmembrane transporter activity	1/202	164/18367	0.83826601653129	0.865840556548767	ABCC4	1
GO:0046873	metal ion transmembrane transporter activity	3/202	430/18367	0.855252997807461	0.881453308462394	ATP2A3/ATP1B1/ATP2C1	3
GO:0031406	carboxylic acid binding	1/202	176/18367	0.858541985054955	0.88291108070062	EGLN3	1
GO:0008234	cysteine-type peptidase activity	1/202	190/18367	0.879021158154152	0.900041229327404	YOD1	1
GO:0008237	metallopeptidase activity	1/202	190/18367	0.879021158154152	0.900041229327404	XPNPEP1	1
GO:0005244	voltage-gated ion channel activity	1/202	201/18367	0.893018604271887	0.910415070588871	CLCN3	1
GO:0022832	voltage-gated channel activity	1/202	201/18367	0.893018604271887	0.910415070588871	CLCN3	1
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	1/202	222/18367	0.915419503453272	0.931236687098253	GTF2B	1
GO:0140097	catalytic activity, acting on DNA	1/202	229/18367	0.92179560462105	0.935702003828696	CHD9	1
GO:0015291	secondary active transmembrane transporter activity	1/202	240/18367	0.930862368087282	0.94287349541744	CLCN3	1
GO:0016791	phosphatase activity	1/202	275/18367	0.953310772817847	0.963539429178554	NT5C3A	1
GO:0022836	gated channel activity	1/202	340/18367	0.977525188332769	0.985897995085084	CLCN3	1
GO:0140098	catalytic activity, acting on RNA	1/202	386/18367	0.986625034069655	0.992949553518819	NT5C3A	1
GO:0005216	ion channel activity	1/202	432/18367	0.99205107009694	0.995440213445209	CLCN3	1
GO:0015267	channel activity	1/202	480/18367	0.995388131065562	0.995440213445209	CLCN3	1
GO:0022803	passive transmembrane transporter activity	1/202	481/18367	0.995440213445209	0.995440213445209	CLCN3	1